TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|115583687|ref|NP_619600.2| pre-mRNA processing factor
8 [Mus musculus]
         (2335 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

18874                                                                 674   0.0  
30886                                                                 272   1e-72
25842                                                                 261   3e-69
17773                                                                 170   5e-42
26296                                                                  32   4.0  
>18874
          Length = 1177

 Score =  674 bits (1740), Expect(2) = 0.0,   Method: Compositional matrix adjust.
 Identities = 328/360 (91%), Positives = 344/360 (95%)
 Frame = -2

Query: 824  PIPFPPLSYKHDTKLLILALERLKEAYSVKSRLNQSQREELGLIEQAYDNPHEALSRIKR 883
            PIPFPPLSYKHDTKLLILALERLKEAYSVKSRLNQSQREELGLIEQAYDNPHEALSRIKR
Sbjct: 1080 PIPFPPLSYKHDTKLLILALERLKEAYSVKSRLNQSQREELGLIEQAYDNPHEALSRIKR 901

Query: 884  HLLTQRAFKEVGIEFMDLYSHLVPVYDVEPLEKITDAYLDQYLWYEADKRRLFPPWIKPA 943
            HLLTQRAFKEVGIEFMDLYSHLVPVYDVEPLEKITDAYLDQYLWYEADKRRLFPPWIKP+
Sbjct: 900  HLLTQRAFKEVGIEFMDLYSHLVPVYDVEPLEKITDAYLDQYLWYEADKRRLFPPWIKPS 721

Query: 944  DTEPPPLLVYKWCQGINNLQDVWETSEGECNVMLESRFEKMYEKIDXXXXXXXXXXIVDH 1003
            D+EPPPLL YKWCQGINNLQDVW+T EGECNVM+ES FEKMYEKID          IVDH
Sbjct: 720  DSEPPPLLTYKWCQGINNLQDVWDTGEGECNVMMESTFEKMYEKIDLTLLNRLLRLIVDH 541

Query: 1004 NIADYMTAKNNVVINYKDMNHTNSYGIIRGLQFASFIVQYYGLVMDLLVLGLHRASEMAG 1063
            NIADYMTAKNNVVINYKDMNHTNSYGIIRGLQFASFIVQ+YGLV+DLLVLGLHRASEM+G
Sbjct: 540  NIADYMTAKNNVVINYKDMNHTNSYGIIRGLQFASFIVQFYGLVLDLLVLGLHRASEMSG 361

Query: 1064 PPQMPNDFLSFQDIATEAAHPIRLFCRYIDRIHIFFRFTADEARDLIQRYLTEHPDPNNE 1123
            PPQMPNDFL+FQD+ TE AHPIRL+ RYIDRIHIFFRF+A+EARDLIQRYLTEHPDPNNE
Sbjct: 360  PPQMPNDFLTFQDVVTETAHPIRLYSRYIDRIHIFFRFSAEEARDLIQRYLTEHPDPNNE 181

Query: 1124 NIVGYNNKKCWPRDARMRLMKHDVNLGRAVFWDIKNRLPRSVTTVQWENSFVSVYSKDNP 1183
            NIVGYNNKKCWPRD+RMRLMKHDVNLGRAVFWDI+NRLPRSVTT+QWE+SFVSVYSKDNP
Sbjct: 180  NIVGYNNKKCWPRDSRMRLMKHDVNLGRAVFWDIQNRLPRSVTTIQWESSFVSVYSKDNP 1

 Score = 45.1 bits (105), Expect(2) = 0.0,   Method: Compositional matrix adjust.
 Identities = 20/37 (54%), Positives = 21/37 (56%)
 Frame = -1

Query: 792  HNYLKDGPYIXXXXXXXXXXXXXHWLESRRFSPIPFP 828
            +NYLK GPYI             HWLESRRFSP P P
Sbjct: 1177 YNYLKXGPYITAEEAVAIYTTMVHWLESRRFSPHPLP 1067
>30886
          Length = 399

 Score =  272 bits (695), Expect = 1e-72,   Method: Composition-based stats.
 Identities = 124/132 (93%), Positives = 130/132 (98%)
 Frame = -2

Query: 1180 KDNPNLLFNMCGFECRILPKCRTSYEEFTHKDGVWNLQNEVTKERTAQCFLRVDDESMQR 1239
            KDNPNLLFNMCGFECR+LPKCRT++EEFTH+DGVWNLQNEVTKERT QCFLRVD+ESM R
Sbjct: 398  KDNPNLLFNMCGFECRVLPKCRTTHEEFTHRDGVWNLQNEVTKERTXQCFLRVDEESMNR 219

Query: 1240 FHNRVRQILMASGSTTFTKIVNKWNTALIGLMTYFREAVVNTQELLDLLVKCENKIQTRI 1299
            FHNRVRQILMASGSTTFTKIVNKWNTALIGLMTYFRE+VVNTQELLDLLVKCENKIQTRI
Sbjct: 218  FHNRVRQILMASGSTTFTKIVNKWNTALIGLMTYFRESVVNTQELLDLLVKCENKIQTRI 39

Query: 1300 KIGLNSKMPSRF 1311
            KIGLNSKMPSRF
Sbjct: 38   KIGLNSKMPSRF 3
>25842
          Length = 431

 Score =  261 bits (666), Expect = 3e-69,   Method: Compositional matrix adjust.
 Identities = 125/143 (87%), Positives = 128/143 (89%)
 Frame = +2

Query: 627 CGFWAAGWRVWLFFMRGITPLLERWLGNLLARQFEGRHSKGVAKTVTKQRVESHFDLELR 686
           CG WA GWRVW+FFMRGITPLLERWLGNLL+RQFEGRHSKGVAKTVTKQRVESHFDLELR
Sbjct: 2   CGIWAPGWRVWMFFMRGITPLLERWLGNLLSRQFEGRHSKGVAKTVTKQRVESHFDLELR 181

Query: 687 AAVMHDILDMMPEGIKQNKARTILQHLSEAWRCWKANIPWKVPGLPTPIENMILRYVKAK 746
           AAVMHDILDMMPEGIKQNKART            + NIPWKVPGLPTPIENMILRYVKAK
Sbjct: 182 AAVMHDILDMMPEGIKQNKARTDPAASV*GLEVLEGNIPWKVPGLPTPIENMILRYVKAK 361

Query: 747 ADWWTNTAHYNRERIRRGATVDK 769
           ADWWTNTAHYNRERIRRGATVDK
Sbjct: 362 ADWWTNTAHYNRERIRRGATVDK 430
>17773
          Length = 445

 Score =  170 bits (431), Expect = 5e-42,   Method: Compositional matrix adjust.
 Identities = 82/83 (98%), Positives = 83/83 (100%)
 Frame = -2

Query: 1799 TTKPINGAIFIFNPRTGQLFLKIIHTSVWAGQKRLGQLAKWKTAEEVAALIRSLPVEEQP 1858
            +TKPINGAIFIFNPRTGQLFLKIIHTSVWAGQKRLGQLAKWKTAEEVAALIRSLPVEEQP
Sbjct: 249  STKPINGAIFIFNPRTGQLFLKIIHTSVWAGQKRLGQLAKWKTAEEVAALIRSLPVEEQP 70

Query: 1859 KQIIVTRKGMLDPLEVHLLDFPN 1881
            KQIIVTRKGMLDPLEVHLLDFPN
Sbjct: 69   KQIIVTRKGMLDPLEVHLLDFPN 1

 Score =  149 bits (376), Expect = 1e-35,   Method: Compositional matrix adjust.
 Identities = 67/75 (89%), Positives = 70/75 (93%)
 Frame = -1

Query: 1421 TLFQKDRHTLAYDKGWRVRTDFKQYQVLKQNPFWWTHQRHDGKLWNLNNYRTDMIQALGG 1480
            TLFQKDRHTLAYDKGWRVRTDFKQYQVLKQNPFWWTHQRHDGKLWNLNNYRTDMIQALGG
Sbjct: 445  TLFQKDRHTLAYDKGWRVRTDFKQYQVLKQNPFWWTHQRHDGKLWNLNNYRTDMIQALGG 266

Query: 1481 VEGILEHTLFKGTYF 1495
            VEGILEH   + ++ 
Sbjct: 265  VEGILEHQAHQRSHL 221
>26296
          Length = 856

 Score = 31.6 bits (70), Expect = 4.0,   Method: Composition-based stats.
 Identities = 15/39 (38%), Positives = 20/39 (51%)
 Frame = -1

Query: 2150 QWGTHQTVHLPSQLPQHEYLKEMEPLGWIHTQPNESPQL 2188
            QWG H  +  P+ +   + L EM P+G     PN S QL
Sbjct: 157  QWGPHPKMEGPTAVEISKQLNEMVPIGQARRAPNVSGQL 41
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|126032329|ref|NP_034236.2| eukaryotic translation
elongation factor 1 alpha 1 [Mus musculus]
         (462 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

15991                                                                 583   0.0  
00709                                                                 453   e-128
22349                                                                 143   1e-34
16686                                                                  64   9e-11
15617                                                                  50   2e-06
04430                                                                  28   0.019
31464                                                                  33   0.31 
14064                                                                  32   0.60 
>15991
          Length = 1629

 Score =  583 bits (1504), Expect(3) = 0.0,   Method: Compositional matrix adjust.
 Identities = 284/336 (84%), Positives = 300/336 (89%)
 Frame = -3

Query: 44   KEAAEMGKGSFKYAWVLDKLKAERERGITIDISLWKFETSKYYVTIIDAPGHRDFIKNMI 103
            +EAAEMGKGSFKYAWVLDKLKAERERGITIDI+LWKFET KYYVTIIDAPGHRDFIKNMI
Sbjct: 1546 EEAAEMGKGSFKYAWVLDKLKAERERGITIDIALWKFETDKYYVTIIDAPGHRDFIKNMI 1367

Query: 104  TGTSQADCAVLIVAAGVGEFEAGISKNGQTREHALLAYTLGVKQLIVGVNKMDSTEPPYS 163
            TGTSQADCAVL+VAAG GEFEAGISK+GQTREHALLAYTLGVKQLIV VNKMDSTEPPYS
Sbjct: 1366 TGTSQADCAVLVVAAGKGEFEAGISKDGQTREHALLAYTLGVKQLIVAVNKMDSTEPPYS 1187

Query: 164  QKRYEEIVKEVSTYIKKIGYNPDTVAFVPISGWNGDNMLEPSANMPWFKGWKVTRKDGSA 223
              R+EEI KEVSTYIKKIGYNP+TVAFVPISGW GDNM+E S  +     WK+ RK+G A
Sbjct: 1186 MDRFEEIKKEVSTYIKKIGYNPNTVAFVPISGWVGDNMMEASTKI--VHKWKIERKEGKA 1013

Query: 224  SGTTLLEALDCILPPTRPTDKPLRLPLQDVYKIGGIGTVPVGRVETGVLKPGMVVTFAPV 283
             G TL EALD ILPPTRPTDK LRLPLQDVYKIGGIGTVPVGRVETG+LKPG VVTFAP 
Sbjct: 1012 EGETLKEALDAILPPTRPTDKALRLPLQDVYKIGGIGTVPVGRVETGILKPGTVVTFAPG 833

Query: 284  NVTTEVKSVEMHHEALSEALPGDNVGFNVKNVSVKDVRRGNVAGDSKNDPPMEAAGFTAQ 343
             +TTEVKSVEMHHE L EALPGDNVGFNVKNVSVKD+RRGNVAGDSKNDPP  A  F AQ
Sbjct: 832  GLTTEVKSVEMHHEQLQEALPGDNVGFNVKNVSVKDIRRGNVAGDSKNDPPKGAKNFYAQ 653

Query: 344  VIILNHPGQISAGYAPVLDCHTAHIACKFAELKEKI 379
            VIILNHPG I AGYAPVLDCHTAHIACKF EL+ ++
Sbjct: 652  VIILNHPGMIHAGYAPVLDCHTAHIACKFEELEREV 545

 Score =  104 bits (259), Expect(3) = 0.0,   Method: Compositional matrix adjust.
 Identities = 46/58 (79%), Positives = 51/58 (87%)
 Frame = -1

Query: 375 LKEKIDRRSGKKLEDGPKFLKSGDAAIVDMVPGKPMCVESFSDYPPLGRFAVRDMRQT 432
           LKEK D RSGKKLED PK +KSGDAA+V +VP KPMCVE+F DYPPLGRFAVRDM+QT
Sbjct: 558 LKEKCDXRSGKKLEDNPKCVKSGDAAMVTLVPSKPMCVEAFVDYPPLGRFAVRDMKQT 385

 Score = 54.3 bits (129), Expect(3) = 0.0,   Method: Compositional matrix adjust.
 Identities = 24/32 (75%), Positives = 26/32 (81%)
 Frame = -2

Query: 17   DSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAE 48
            DSGKSTTTGHLIYKCGGIDKR IEK  +   +
Sbjct: 1625 DSGKSTTTGHLIYKCGGIDKRVIEKLRRSCRD 1530
>00709
          Length = 1076

 Score =  453 bits (1166), Expect = e-128,   Method: Compositional matrix adjust.
 Identities = 219/261 (83%), Positives = 235/261 (90%), Gaps = 4/261 (1%)
 Frame = -2

Query: 1   MGKEKTHINIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAEMGKGSFKYAWVL 60
           MGKEK HINIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEA EMGKGSFKYAWVL
Sbjct: 907 MGKEKVHINIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAQEMGKGSFKYAWVL 728

Query: 61  DKLKAERERGITIDISLWKFETSKYYVTIIDAPGHRDFIKNMITGTSQADCAVLIVAAGV 120
           DKLKAERERGITIDI+LWKFET+KYYVTIIDAPGHRDFIKNMITGTSQADCAVLIVA+G 
Sbjct: 727 DKLKAERERGITIDIALWKFETTKYYVTIIDAPGHRDFIKNMITGTSQADCAVLIVASGT 548

Query: 121 GEFEAGISKNGQTREHALLAYTLGVKQLIVGVNKMDSTEPPYSQKRYEEIVKEVSTYIKK 180
           GEFEAGISK GQTREHALLAYTLGVKQLI+GVNKMDST P YS+ R+ EI KEVS YIKK
Sbjct: 547 GEFEAGISKEGQTREHALLAYTLGVKQLIIGVNKMDSTSPAYSETRFNEIQKEVSGYIKK 368

Query: 181 IGYNPDTVAFVPISGWNGDNMLEPSANMPWFKGWKVTRKDGS----ASGTTLLEALDCIL 236
           IG+NP  VAFVPISG++GDNM+  S  M W+KGW++ RK+G+    ASG TL +ALD IL
Sbjct: 367 IGFNPKAVAFVPISGFHGDNMIXESEKMGWYKGWEIERKEGTKEVKASGKTLFDALDSIL 188

Query: 237 PPTRPTDKPLRLPLQDVYKIG 257
           PPTRPT KPLRLPLQDVYKIG
Sbjct: 187 PPTRPTGKPLRLPLQDVYKIG 125

 Score = 54.7 bits (130), Expect = 8e-08,   Method: Compositional matrix adjust.
 Identities = 28/46 (60%), Positives = 32/46 (69%)
 Frame = -3

Query: 237 PPTRPTDKPLRLPLQDVYKIGGIGTVPVGRVETGVLKPGMVVTFAP 282
           PP  P       P +   ++ GIGTVPVGRVETG+LKPGMVVTFAP
Sbjct: 186 PPLVPLASLCVCPCRMSTRLEGIGTVPVGRVETGILKPGMVVTFAP 49
>22349
          Length = 662

 Score =  143 bits (361), Expect = 1e-34,   Method: Compositional matrix adjust.
 Identities = 71/153 (46%), Positives = 101/153 (66%), Gaps = 1/153 (0%)
 Frame = -2

Query: 5   KTHINIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAEMGKGSFKYAWVLDKLK 64
           K HIN+V IGHVD+GKST  GHL+Y  G +DKRT+EK+E+EA E  + ++  +W LD   
Sbjct: 499 KDHINVVFIGHVDAGKSTIGGHLLYLTGMVDKRTLEKYEREAKEKNRETWYLSWALDTNN 320

Query: 65  AERERGITIDISLWKFETSKYYVTIIDAPGHRDFIKNMITGTSQADCAVLIVAAGVGEF- 123
            ERE+G T+++    FET   + T++DAPGH+ F+ NMI G SQAD A+L+++A  GEF 
Sbjct: 319 EEREKGKTVEVGRAFFETELKHFTVLDAPGHKSFVPNMICGASQADLAILVISARRGEF* 140

Query: 124 EAGISKNGQTREHALLAYTLGVKQLIVGVNKMD 156
           +  +S+  +           GV+ LIV +NKMD
Sbjct: 139 DWFLSEEARHVSMPCW*RRQGVRHLIVLINKMD 41
>16686
          Length = 689

 Score = 64.3 bits (155), Expect = 9e-11,   Method: Compositional matrix adjust.
 Identities = 42/144 (29%), Positives = 72/144 (50%)
 Frame = -2

Query: 289 VKSVEMHHEALSEALPGDNVGFNVKNVSVKDVRRGNVAGDSKNDPPMEAAGFTAQVIILN 348
           VK+V +   +   A  GD+V F++ N+ +  V  G V  D  + P   A    A+V++ N
Sbjct: 649 VKNVTVDDLSSQLAFAGDHVTFSLTNIDMTSVNVGFVLCDPMS-PTKCAIRIRAKVVLFN 473

Query: 349 HPGQISAGYAPVLDCHTAHIACKFAELKEKIDRRSGKKLEDGPKFLKSGDAAIVDMVPGK 408
               I+ G+  V      +    F  L   I++ +G  +++ PK L    +AIV++   +
Sbjct: 472 LDLPITRGFPVVFHXQCVNEPAVFKRLVATINKSTGDIVKNRPKCLTKNSSAIVELEFER 293

Query: 409 PMCVESFSDYPPLGRFAVRDMRQT 432
            +CVE +S+Y  LGRF +R+   T
Sbjct: 292 SVCVELYSEYRDLGRFMLRNSGHT 221
>15617
          Length = 595

 Score = 50.4 bits (119), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 42/133 (31%), Positives = 62/133 (46%), Gaps = 18/133 (13%)
 Frame = -3

Query: 2   GKEKTHINIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAEMGKGSFKYAWVLD 61
           G++K   N+ VI HVD GKST T  L+ K G I           +A+ G+  F      D
Sbjct: 449 GQQKNIRNMSVIAHVDHGKSTLTDSLVSKAGII----------ASAKAGETRFT-----D 315

Query: 62  KLKAERERGITID---ISLW--------KF-------ETSKYYVTIIDAPGHRDFIKNMI 103
             K E+ER ITI    ISL+        K+       + + + + +ID+PGH DF   + 
Sbjct: 314 TRKDEQERCITIKSTAISLYYELKKDDMKYIKQDYDQDNNAFLINLIDSPGHVDFSSEVT 135

Query: 104 TGTSQADCAVLIV 116
                 D A+++V
Sbjct: 134 AALRVTDGALVVV 96
>04430
          Length = 2037

 Score = 28.5 bits (62), Expect(2) = 0.019,   Method: Compositional matrix adjust.
 Identities = 13/13 (100%), Positives = 13/13 (100%)
 Frame = -2

Query: 258  GIGTVPVGRVETG 270
            GIGTVPVGRVETG
Sbjct: 2027 GIGTVPVGRVETG 1989

 Score = 26.9 bits (58), Expect(2) = 0.019,   Method: Compositional matrix adjust.
 Identities = 14/22 (63%), Positives = 16/22 (72%)
 Frame = -1

Query: 270  GVLKPGMVVTFAPVNVTTEVKS 291
            G+LKPGMVVT  P  V+TEV  
Sbjct: 1992 GILKPGMVVTL-PQPVSTEVSC 1930
>31464
          Length = 946

 Score = 32.7 bits (73), Expect = 0.31,   Method: Compositional matrix adjust.
 Identities = 23/89 (25%), Positives = 35/89 (39%)
 Frame = +1

Query: 238 PTRPTDKPLRLPLQDVYKIGGIGTVPVGRVETGVLKPGMVVTFAPVNVTTEVKSVEMHHE 297
           P R  D P    +   + +   GTV  G   +G +     V    + V  +VKS++M   
Sbjct: 259 PRRNPDGPFIFSVDHCFSLRXQGTVLTGTAISGSVAVNDTVEIPAMKVQKKVKSMQMFRN 438

Query: 298 ALSEALPGDNVGFNVKNVSVKDVRRGNVA 326
            +   + GD  G  V     K + RG V 
Sbjct: 439 PVDRLVQGDRAGICVTQFDPKLLERGLVC 525
>14064
          Length = 1723

 Score = 32.0 bits (71), Expect = 0.60,   Method: Compositional matrix adjust.
 Identities = 21/66 (31%), Positives = 33/66 (50%), Gaps = 2/66 (3%)
 Frame = +2

Query: 81  ETSKYYVTIIDAPGHRDFIKNMITGTSQA--DCAVLIVAAGVGEFEAGISKNGQTREHAL 138
           ++S   +T+ID  GH  +++  I G +    D A+L+V+A  G         G T+EH  
Sbjct: 122 QSSSKLITLIDLAGHHRYLRTTIVGLTGNCPDFAMLVVSATSGIV-------GMTKEHLG 280

Query: 139 LAYTLG 144
            A  LG
Sbjct: 281 YALALG 298
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|146231996|ref|NP_067498.4| HECT, UBA and WWE domain
containing 1 [Mus musculus]
         (4378 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

02386                                                                 739   0.0  
05501                                                                 326   1e-88
35625                                                                 224   5e-67
13725                                                                 183   1e-45
30230                                                                 183   1e-45
19989                                                                 122   4e-27
21239                                                                  96   3e-19
15511                                                                  94   2e-18
21309                                                                  69   8e-18
19738                                                                  70   5e-16
05524                                                                  60   5e-12
33148                                                                  59   4e-08
19350                                                                  40   0.016
31463                                                                  38   0.086
19756                                                                  38   0.10 
>02386
          Length = 2222

 Score =  739 bits (1907), Expect = 0.0,   Method: Compositional matrix adjust.
 Identities = 347/442 (78%), Positives = 393/442 (88%), Gaps = 3/442 (0%)
 Frame = +2

Query: 3940 SREPSSMHISSSLPPDTQKFLRFAETHRTVLNQILRQSTTHLADGPFAVLVDYIRVLDFD 3999
            +RE S+  I+  LPPDTQKFL+FAETHRTVLNQILRQST  LADGPF+VLVD+ R+LDFD
Sbjct: 89   TRENSAACITH-LPPDTQKFLKFAETHRTVLNQILRQSTLPLADGPFSVLVDHTRMLDFD 265

Query: 4000 VKRKYFRQELERLDEGLRKEDMAVHVRRDHVFEDSYRELHRKSPEEMKNRLYIVFEGEEG 4059
            VKR+YFRQELER++EG+R+ED+ VHVRR+HVFEDS+REL R++P+E K R YIVFEGEEG
Sbjct: 266  VKRRYFRQELERMEEGMRREDLPVHVRREHVFEDSFRELFRRNPDEWKQRFYIVFEGEEG 445

Query: 4060 QDAGGLLREWYMIISREMFNPMYALFRTSPGDRVTYTINPSSHCNPNHLSYFKFVGRIVA 4119
            QDAGGLLREWY+IISRE+FN  Y LF+  P D VTYTINPSSH N NHLSYFKFVGRI+A
Sbjct: 446  QDAGGLLREWYLIISREIFNENYVLFKRYPRDGVTYTINPSSHFNSNHLSYFKFVGRIIA 625

Query: 4120 KAVYDNRLLECYFTRSFYKHILGKSVRYTDMESEDYHFYQGLVYLLENDVSTLGY---DL 4176
            KA+YDN+LLECYFTRSFYKH+LG  V+YTDME ED  FYQ LV+LLEND++ +G    DL
Sbjct: 626  KAIYDNKLLECYFTRSFYKHVLGLPVKYTDMECEDIMFYQSLVFLLENDITDMGAALGDL 805

Query: 4177 TFSTEVQEFGVCEVRDLKPNGANILVTEENKKEYVHLVCQMRMTGAIRKQLAAFLEGFYE 4236
             FS EV+EFGV E RDL  NG+NI VTEENK+EYV LVCQM+MTGAIR+QL AFLEGFY+
Sbjct: 806  NFSAEVEEFGVRETRDLIENGSNIGVTEENKREYVKLVCQMKMTGAIRQQLNAFLEGFYD 985

Query: 4237 IIPKRLISIFTEQELELLISGLPTIDIDDLKSNTEYHKYQSNSIQIQWFWRALRSFDQAD 4296
            IIPK+L++IFTEQELELLISGLPTIDIDDLK+NTEYHKYQ  S+QIQWFWRALRSFDQA+
Sbjct: 986  IIPKKLVAIFTEQELELLISGLPTIDIDDLKANTEYHKYQPTSLQIQWFWRALRSFDQAE 1165

Query: 4297 RAKFLQFVTGTSKVPLQGFAALEGMNGIQKFQIHRDDRSTDRLPSAHTCFNQLDLPAYES 4356
            RA FLQFVTGTSKVPLQGFA LEGMNG QKFQIHRDDRSTDRLPSAHTCFNQLDLPAYE+
Sbjct: 1166 RANFLQFVTGTSKVPLQGFATLEGMNGHQKFQIHRDDRSTDRLPSAHTCFNQLDLPAYET 1345

Query: 4357 FEKLRHMLLLAIQECSEGFGLA 4378
            ++KLR MLLLA+ ECSEGFGLA
Sbjct: 1346 YDKLRKMLLLAVSECSEGFGLA 1411
>05501
          Length = 1740

 Score =  326 bits (836), Expect = 1e-88,   Method: Compositional matrix adjust.
 Identities = 153/346 (44%), Positives = 229/346 (66%)
 Frame = -1

Query: 4031 FEDSYRELHRKSPEEMKNRLYIVFEGEEGQDAGGLLREWYMIISREMFNPMYALFRTSPG 4090
            +EDS+ ++ R  P +++ RLYI+F+GEEG D GG+ REW+  +S ++ NPMY LF  +  
Sbjct: 1683 YEDSFAQIMRLQPFDLRRRLYIIFKGEEGLDYGGVAREWFFHLSHDVLNPMYCLFEYASN 1504

Query: 4091 DRVTYTINPSSHCNPNHLSYFKFVGRIVAKAVYDNRLLECYFTRSFYKHILGKSVRYTDM 4150
            +  +  INP+S  NP+HL YF+F+GR +A A+Y  + ++  FT  FYK +L K +   D+
Sbjct: 1503 NNYSLQINPASSVNPDHLLYFRFIGRFIAMALYHGKFIDSGFTLPFYKRMLSKKLTLKDL 1324

Query: 4151 ESEDYHFYQGLVYLLENDVSTLGYDLTFSTEVQEFGVCEVRDLKPNGANILVTEENKKEY 4210
            E+ D  ++Q L ++ +N+V   G +L F  + +  G  E  +LKP G+ I VTEENK+EY
Sbjct: 1323 ETIDGEYFQSLQWVKDNNVEESGLELFFCADFEVLGKVENHELKPGGSEIKVTEENKEEY 1144

Query: 4211 VHLVCQMRMTGAIRKQLAAFLEGFYEIIPKRLISIFTEQELELLISGLPTIDIDDLKSNT 4270
            ++L+ Q R +  + +Q  AFLEGF E++P + +  F E+ELEL++ G+  +D+DD + NT
Sbjct: 1143 LNLMTQWRFSRGVEEQTKAFLEGFNEVVPLQWLQYFDERELELMLCGMQEVDVDDWERNT 964

Query: 4271 EYHKYQSNSIQIQWFWRALRSFDQADRAKFLQFVTGTSKVPLQGFAALEGMNGIQKFQIH 4330
             Y  YQ NS Q+ WFW+ +R  D   R + LQFVTGT ++P+ GFA L G NG Q+F I 
Sbjct: 963  IYRHYQRNSKQVTWFWKFVREIDNEKRTRLLQFVTGTCRLPVGGFAELMGSNGPQRFCIE 784

Query: 4331 RDDRSTDRLPSAHTCFNQLDLPAYESFEKLRHMLLLAIQECSEGFG 4376
            +  + T  LP +HTCFN++DLP Y S+E+L   L LAI+E +EGFG
Sbjct: 783  KVGKET-WLPRSHTCFNRIDLPPYRSYEQLVEKLNLAIEE-TEGFG 652
>35625
          Length = 535

 Score =  224 bits (571), Expect(2) = 5e-67,   Method: Compositional matrix adjust.
 Identities = 106/152 (69%), Positives = 127/152 (83%)
 Frame = -2

Query: 273 RLQAVQARLHAISILVYSNALQESANSILYNGLIEELVDVLQITDKQLMEIKAASLRTLT 332
           RLQ VQARL A+SILVY+NA+QE+ N ILY GLIEELVD+++I D  L++IKAA+LRTLT
Sbjct: 534 RLQCVQARLQAVSILVYANAIQENLNVILYPGLIEELVDIIEIADPGLVDIKAAALRTLT 355

Query: 333 SIVHLERTPKLSSIIDCTGTASYHGFLPVLVRNCIQAMIDPSMDPYPHQFATALFSFLYH 392
           SI+H++R PKL  IID TG ASYHGFLPVLVR CIQ MI+P  +P+P Q+ATALFSFLYH
Sbjct: 354 SIIHIDRNPKLVIIIDTTGAASYHGFLPVLVRTCIQHMIEPEQEPFPQQYATALFSFLYH 175

Query: 393 LASYDAGGEALVSCGMMEALLKVIKFLGDEQD 424
           +ASY+ G EALV+CGMMEALLKVI +    QD
Sbjct: 174 MASYENGVEALVACGMMEALLKVINWYSQGQD 79

 Score = 52.4 bits (124), Expect(2) = 5e-67,   Method: Composition-based stats.
 Identities = 22/26 (84%), Positives = 25/26 (96%)
 Frame = -1

Query: 425 QITFVTRAVRVVDLITNLDMAAFQSH 450
            ITFVTRAVRV+DLITN+DMAAFQ+H
Sbjct: 79  HITFVTRAVRVIDLITNMDMAAFQAH 2
>13725
          Length = 700

 Score =  183 bits (465), Expect = 1e-45,   Method: Composition-based stats.
 Identities = 93/228 (40%), Positives = 129/228 (56%)
 Frame = +2

Query: 4003 KYFRQELERLDEGLRKEDMAVHVRRDHVFEDSYRELHRKSPEEMKNRLYIVFEGEEGQDA 4062
            K  R E + L    +     + V R+ +FEDSYR++ +   +E++ RL + F GEEG D 
Sbjct: 2    KVLRHEFQSLQP--QTGHCRLEVSREEIFEDSYRQVMKMRSKELRKRLMVKFHGEEGLDY 175

Query: 4063 GGLLREWYMIISREMFNPMYALFRTSPGDRVTYTINPSSHCNPNHLSYFKFVGRIVAKAV 4122
            GG+ REW+ ++S EM NP Y LF+ S  D  T  INP S  NP HLSYF FVGR++  A+
Sbjct: 176  GGVAREWFYLLSHEMLNPYYGLFQYSREDIYTLQINPDSGVNPEHLSYFHFVGRVIGMAI 355

Query: 4123 YDNRLLECYFTRSFYKHILGKSVRYTDMESEDYHFYQGLVYLLENDVSTLGYDLTFSTEV 4182
            +    L+  FT  FYK +LGK     D+ES D   ++ L ++LEN++  +  + TFS E 
Sbjct: 356  FHGHYLDGGFTMPFYKQLLGKPATLEDLESVDPDLHRSLCWMLENNIENV-LEHTFSVEH 532

Query: 4183 QEFGVCEVRDLKPNGANILVTEENKKEYVHLVCQMRMTGAIRKQLAAF 4230
              FG     +LKP G +  VTE+NK EYV L    R+   I  Q  A 
Sbjct: 533  NSFGKLREYELKPGGNDTKVTEDNKHEYVRLYVHWRLMRGIEAQFLAL 676
>30230
          Length = 738

 Score =  183 bits (464), Expect = 1e-45,   Method: Compositional matrix adjust.
 Identities = 109/240 (45%), Positives = 146/240 (60%), Gaps = 9/240 (3%)
 Frame = +2

Query: 1610 LQSNSNNWRWFDDRSGRWCSYSASNNSTIDSAWKSGETSVRFTAGRRRYTVQFTTMVQVN 1669
            L++ S+ W+WFDD +GRWC YS  NN TI  A+ +G+ SVRF AGRR+Y VQFTTM+Q+N
Sbjct: 2    LRAGSSTWKWFDDSTGRWCKYSIGNNKTIHDAYMAGQXSVRFQAGRRKYCVQFTTMMQLN 181

Query: 1670 EETGNRRPVMLTLLRVPR------LSKNSKSSNGQXXXXXXXXXXXXDIKHKENKGNDIP 1723
            EETGNRRPVML+   VP       ++K  K                  +  KE+    + 
Sbjct: 182  EETGNRRPVMLS---VPTSEEKLAIAKEDKQKTLITAAAMVPASSATPVTVKES----VS 340

Query: 1724 LALESTNTEKEASLDETK---IGEILIQGLTEDMVTVLIRACVSMLGVPVDPDTLHATLR 1780
            +  E    E E    E K      I +  L ED +T +I + VS++ +PV+ +TLHA LR
Sbjct: 341  VKTEEGKMETETGPVEEKKPATTTISLVRLNEDQITTIISSLVSLISIPVESETLHALLR 520

Query: 1781 LCLRLTRDHKYAMMFAELKSTRMILNLTQSSGFNGFTPLVTLLLRHIIEDPCTLRHTMEK 1840
            L LRLTR+H +A+ FA+L+  RM+LNLTQS  F GF  L TLL RH++++P  LRH MEK
Sbjct: 521  LMLRLTREHGHAVQFAQLRGPRMLLNLTQSVAFPGFLSLATLLFRHVLDEPTALRHCMEK 700
>19989
          Length = 464

 Score =  122 bits (305), Expect = 4e-27,   Method: Composition-based stats.
 Identities = 57/82 (69%), Positives = 65/82 (79%)
 Frame = -2

Query: 575 SLQDNGLTDVMLHALLIKDVPATREVLGSLPNVFSALCLNARGLQSFVQCQPFERLFKVL 634
           SL DN +  +      +  VPATREVL SLPNVFSALCLNARGL++FV C+PF+RLFKVL
Sbjct: 262 SLFDNKVF*IGFELNGVNQVPATREVLASLPNVFSALCLNARGLEAFVACRPFDRLFKVL 83

Query: 635 LSPDYLPAMRRRRSSDPLGDTA 656
           LSPDYLPAMRRRRS+DP G  A
Sbjct: 82  LSPDYLPAMRRRRSADPFGQYA 17
>21239
          Length = 1264

 Score = 95.9 bits (237), Expect = 3e-19,   Method: Compositional matrix adjust.
 Identities = 70/231 (30%), Positives = 108/231 (46%), Gaps = 8/231 (3%)
 Frame = +1

Query: 4156 HFYQGLVYLLENDVSTLGYDLTFSTEVQEFGVC-----EVRDLKPNGANILVTEENKKEY 4210
            +F+   + L +N +  LG ++    ++Q+ G+         +LK  G +I VT  N  EY
Sbjct: 1    YFFAMFIVLSQNGILLLGSEVLIQ-DIQDLGLYFHLPGYNIELKKGGKDIPVTLHNLHEY 177

Query: 4211 VHLVCQMRMTGAIRKQLAAFLEGFYEIIPKRLISIFTEQELELLISG--LPTIDIDDLKS 4268
            + LV    +   + +Q  AF EGF  +     +  F  +ELE L  G      ++  L  
Sbjct: 178  LQLVIHWSLVEGVSRQFEAFREGFESVFSLSSLQCFYPEELEQLFCGSQWGPWEVKMLME 357

Query: 4269 NTE-YHKYQSNSIQIQWFWRALRSFDQADRAKFLQFVTGTSKVPLQGFAALEGMNGIQKF 4327
            N    H Y  +S  + + ++ L SFD   +  FLQFVTG+ ++P+ GF +L     I + 
Sbjct: 358  NCRPDHGYTHDSKAVVFLYQLLASFDLQQQRHFLQFVTGSPRLPVGGFRSLTPPLTIVRK 537

Query: 4328 QIHRDDRSTDRLPSAHTCFNQLDLPAYESFEKLRHMLLLAIQECSEGFGLA 4378
                 +   D LPS  TC N L LP Y S + +RH L  A  E    F L+
Sbjct: 538  TFEAGENPDDFLPSVMTCVNYLKLPDYSSIDIMRHKLHTAASEGQLSFHLS 690
>15511
          Length = 1754

 Score = 93.6 bits (231), Expect = 2e-18,   Method: Compositional matrix adjust.
 Identities = 66/189 (34%), Positives = 95/189 (50%), Gaps = 4/189 (2%)
 Frame = -2

Query: 2493 IIEFDNMF-SSATDIPPSPGNIPTTHPLMVRHADHXXXXXXXXXXXXXXXXXIGRSQ-RT 2550
            I + DN   +S   +PP+P  +   HPL+VR +D+                 + RS+ R 
Sbjct: 1135 IHDSDNATEASVPSLPPAPSGVTAAHPLLVRQSDNLLNVR------------VPRSRHRA 992

Query: 2551 LRQLTANTGHTIHV--HYPGNRQPNPPLILQRLLGPSAAADIXXXXXXXXXXXRGRARLL 2608
              + T +T HT HV  H   + +PNPP+ILQRLLGP+A ADI                  
Sbjct: 991  SYRFTPST-HTFHVNMHGAASSRPNPPVILQRLLGPNATADILQL--------------- 860

Query: 2609 VGNDDVHIIARSDDELLDDFFHDQSTATSQAGTLSSIPTALTRWTEECKVLDAESMHDCV 2668
                  H + +       D + D  +  S  G +SSIP+ LTRWTEE +VLD +S+HDCV
Sbjct: 859  -----THTLPQ-------DQYSDSLSVGS--GVMSSIPSTLTRWTEEARVLDGDSVHDCV 722

Query: 2669 SVVKVPIVN 2677
            +V+K  +V+
Sbjct: 721  TVIKPEVVD 695
>21309
          Length = 730

 Score = 68.6 bits (166), Expect(2) = 8e-18,   Method: Composition-based stats.
 Identities = 31/64 (48%), Positives = 35/64 (54%)
 Frame = -2

Query: 1076 GSPVRQRXXXXXXXXXXXXXXXXXXXXXXLTKLLTKGLSWQPPPYTPTPRFRLTFFICSV 1135
            GSPVRQR                      LT+LL  GLSW+PP Y P P+ RLTF +CSV
Sbjct: 192  GSPVRQRRSQQTANQGGSPSPAARAVASALTRLLGNGLSWEPPHYAPVPKLRLTFLVCSV 13

Query: 1136 GFTS 1139
            GFTS
Sbjct: 12   GFTS 1

 Score = 43.1 bits (100), Expect(2) = 8e-18,   Method: Compositional matrix adjust.
 Identities = 20/45 (44%), Positives = 26/45 (57%)
 Frame = -1

Query: 1035 KSKITPAMAARIKQIKPXXXXXXXXXXXXXXXFGLLVKLCVGSPV 1079
            KSK++P + A+I+Q+KP               FGLLVKLCVG P 
Sbjct: 316  KSKVSPVLQAQIRQLKPLLSVSSRLGRALAELFGLLVKLCVGLPC 182

 Score = 35.4 bits (80), Expect = 0.55,   Method: Composition-based stats.
 Identities = 11/19 (57%), Positives = 17/19 (89%)
 Frame = -2

Query: 960 LPSGCEFGQADMQKLVPKD 978
           LP GC+FG+ADM +++P+D
Sbjct: 729 LPQGCQFGRADMDRIIPQD 673
>19738
          Length = 375

 Score = 70.5 bits (171), Expect(2) = 5e-16,   Method: Composition-based stats.
 Identities = 32/76 (42%), Positives = 49/76 (64%)
 Frame = +2

Query: 4192 DLKPNGANILVTEENKKEYVHLVCQMRMTGAIRKQLAAFLEGFYEIIPKRLISIFTEQEL 4251
            +L P G NI VT +NK  Y+  + Q R+  ++++++ +FL G  E+IP  L+SIF E EL
Sbjct: 8    ELMPGGGNIRVTNKNKLSYLDCLAQYRLATSVKEEVESFLRGLNELIPDNLLSIFDEYEL 187

Query: 4252 ELLISGLPTIDIDDLK 4267
            ELL+ G+ T  + D K
Sbjct: 188  ELLMCGMGTYSLADFK 235

 Score = 35.0 bits (79), Expect(2) = 5e-16,   Method: Compositional matrix adjust.
 Identities = 13/30 (43%), Positives = 19/30 (63%)
 Frame = +1

Query: 4282 IQWFWRALRSFDQADRAKFLQFVTGTSKVP 4311
            + WFW  + SF +   A+ LQF TG S++P
Sbjct: 280  LDWFWTVIASFTEEQMARLLQFTTGCSQLP 369
>05524
          Length = 2623

 Score = 60.5 bits (145), Expect(2) = 5e-12,   Method: Composition-based stats.
 Identities = 38/119 (31%), Positives = 58/119 (48%), Gaps = 1/119 (0%)
 Frame = +2

Query: 4254 LISGLPTIDIDDLKSNTEYHKYQSNSIQIQWFWRALRSFDQADRAKFLQFVTGTSKVPLQ 4313
            L  G P I +  LKS   Y   ++ +  +QWFW  +  F  A+R+ FL+FV G +++P +
Sbjct: 485  LWCGSPDIPLTLLKSVATYKGIEATAPLVQWFWEVMDEFSTAERSLFLRFVWGRTRLP-R 661

Query: 4314 GFAALEGMNGIQKFQIHRDDRSTDR-LPSAHTCFNQLDLPAYESFEKLRHMLLLAIQEC 4371
              A   G + +   Q+       D  LP ++TCF  L +P Y     L+  L  AI  C
Sbjct: 662  TIADFRGRDFV--LQVLDKYNPPDHFLPESYTCFFLLKMPRYSDKLVLKEKLKYAIHFC 832

 Score = 31.2 bits (69), Expect(2) = 5e-12,   Method: Compositional matrix adjust.
 Identities = 15/54 (27%), Positives = 29/54 (53%)
 Frame = +1

Query: 4202 VTEENKKEYVHLVCQMRMTGAIRKQLAAFLEGFYEIIPKRLISIFTEQELELLI 4255
            +  +N+ +Y+ +    R+     +Q+    EG   +IP  L+S+FT  ELE ++
Sbjct: 334  INPDNRADYIKMAINYRLQ-EFDQQVRWVREGMSRVIPVPLLSLFTGLELETMV 492
>33148
          Length = 687

 Score = 59.3 bits (142), Expect = 4e-08,   Method: Composition-based stats.
 Identities = 35/101 (34%), Positives = 51/101 (50%), Gaps = 4/101 (3%)
 Frame = +3

Query: 4266 LKSNTEYHKYQSNSIQIQWFWRALRSFDQADRAKFLQFVTGTSKVPLQGFAALEGMNGIQ 4325
            L   T Y   +   I++++FW A+++F   DR++FL+FVTG  ++P    A L    G  
Sbjct: 18   LSKTTYYDDLEETDIRVKYFWEAMKAFSNEDRSRFLRFVTGRRRLP----APLVISTG-- 179

Query: 4326 KFQIHRDDRSTDRLPSAHTCFNQLDLPAYESF----EKLRH 4362
                     + D LP + TC N L LP Y S     EKLR+
Sbjct: 180  ------KGDTIDSLPESSTCANMLYLPYYSSAKVAEEKLRY 284
>19350
          Length = 428

 Score = 40.4 bits (93), Expect = 0.016,   Method: Compositional matrix adjust.
 Identities = 23/74 (31%), Positives = 38/74 (51%), Gaps = 1/74 (1%)
 Frame = -3

Query: 4089 PGDRVTYTINPSSHCN-PNHLSYFKFVGRIVAKAVYDNRLLECYFTRSFYKHILGKSVRY 4147
            PG R  Y+  P +  N P  L+ F+ VGRI+   +  N +   +  R   K++LG+S+ +
Sbjct: 243  PGKRGYYS--PRAGRNTPERLNAFRNVGRIMGLCLLQNEICPLFLNRHVLKYVLGRSISW 70

Query: 4148 TDMESEDYHFYQGL 4161
             D+   D   Y+ L
Sbjct: 69   HDLAFFDPVMYESL 28
>31463
          Length = 495

 Score = 38.1 bits (87), Expect = 0.086,   Method: Compositional matrix adjust.
 Identities = 21/42 (50%), Positives = 26/42 (61%)
 Frame = +1

Query: 4337 DRLPSAHTCFNQLDLPAYESFEKLRHMLLLAIQECSEGFGLA 4378
            DRLP+A TC N L LP ++  + LR  LL AI E   GF L+
Sbjct: 16   DRLPTASTCMNLLKLPEFKDEKTLRTKLLYAI-ESGAGFELS 138
>19756
          Length = 431

 Score = 37.7 bits (86), Expect = 0.10,   Method: Compositional matrix adjust.
 Identities = 18/40 (45%), Positives = 23/40 (57%)
 Frame = -1

Query: 1643 KSGETSVRFTAGRRRYTVQFTTMVQVNEETGNRRPVMLTL 1682
            + GE  +  +A  R Y V F TM Q+NE+TG  RPV   L
Sbjct: 383  RQGEDEMTLSAMGRIYIVDFNTMQQINEDTGTARPVQRKL 264
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|148747128|ref|NP_032434.3| intergral membrane protein
1 [Mus musculus]
         (705 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

08971                                                                 753   0.0  
03996                                                                  39   0.006
08629                                                                  29   6.3  
02610                                                                  28   9.6  
>08971
          Length = 3836

 Score =  753 bits (1945), Expect = 0.0,   Method: Compositional matrix adjust.
 Identities = 360/443 (81%), Positives = 398/443 (89%)
 Frame = -3

Query: 7    LRLSYEKQDTLLKLLILSMAAVLSFSTRLFAVLRFESVIHEFDPYFNYRTTRFLAEEGFY 66
            LR+S +KQDTLLK+++L++AAVLSFSTRLF+VLRFESVIHEFDPYFNYRTTRFLAEEGFY
Sbjct: 3711 LRMSPDKQDTLLKMMVLAIAAVLSFSTRLFSVLRFESVIHEFDPYFNYRTTRFLAEEGFY 3532

Query: 67   KFHNWFDDRAWYPLGRIIGGTIYPGLMITSAAIYHVLHFFHITIDIRNVCVFLAPLFSSF 126
             FHNWFDDRAWYPLGRIIGGTIYPGLM+TSAAIYHVL+FF+ITID+RNVCVFLAPLFSSF
Sbjct: 3531 NFHNWFDDRAWYPLGRIIGGTIYPGLMVTSAAIYHVLNFFNITIDVRNVCVFLAPLFSSF 3352

Query: 127  TTIVTYHLTKELKDXXXXXXXXXMIAVVPGYISRSVAGSYDNEGIAIFCMLLTYYMWIKA 186
            TTIVT+ LTKELKD         M+A+VPGYISRSVAGSYDNEGIAIFCMLLTYY+WIKA
Sbjct: 3351 TTIVTFFLTKELKDASAGLVAASMLAIVPGYISRSVAGSYDNEGIAIFCMLLTYYLWIKA 3172

Query: 187  VKTGSIYWAAKCALAYFYMVSSWGGYVFLINLIPLHVLVLMLTGRFSHRIYVAYCTVYCL 246
            VKTGSIYW A C+LAYFYMVSSWGGYVFLINLIPLHVL LM+TGRFSH+IY+AY TVYCL
Sbjct: 3171 VKTGSIYWGALCSLAYFYMVSSWGGYVFLINLIPLHVLALMVTGRFSHKIYLAYSTVYCL 2992

Query: 247  GTILSMQISFVGFQPVLSSEHMAAFGVFGLCQIHAFVDYLRSKLNPQQFEVLFRSVISLV 306
            GT+LSMQISFVGFQPV SSEHMAA GVFGLCQIHAFVDYLRS+L+ +QF +LFRS++ L 
Sbjct: 2991 GTLLSMQISFVGFQPVQSSEHMAALGVFGLCQIHAFVDYLRSRLSREQFNLLFRSLVLLT 2812

Query: 307  GFVLLTVGALLMLTGKISPWTGRFYSLLDPSYAKNNIPIIASVSEHQPTTWSSYYFDLQL 366
            G +     A+    GKISPWTGRFYSLLDPSYAKNNIPIIASVSEHQPTTWSS+YFDLQL
Sbjct: 2811 GTIAFGAAAVATAMGKISPWTGRFYSLLDPSYAKNNIPIIASVSEHQPTTWSSFYFDLQL 2632

Query: 367  LVFMFPVGLYYCFSNLSDARIFIIMYGVTSMYFSAVMVRLMLVLAPVMCILSGIGVSQVL 426
            LVFMFPVGLY+CFS L+DA IFI+MYGVTS+YF+ VMVRLMLVLAPVMCILSGIGVS +L
Sbjct: 2631 LVFMFPVGLYFCFSKLTDANIFIVMYGVTSIYFAGVMVRLMLVLAPVMCILSGIGVSAIL 2452

Query: 427  STYMKNLDISRPDKKSKKQQDST 449
            + YMKNLD SR DK  K +   T
Sbjct: 2451 TAYMKNLDSSRKDKNXKNRTPPT 2383

 Score =  424 bits (1091), Expect = e-119,   Method: Compositional matrix adjust.
 Identities = 204/269 (75%), Positives = 227/269 (84%), Gaps = 3/269 (1%)
 Frame = -2

Query: 437  RPDKKSKKQQDSTYPIKNEVASGMILVMAFFLITYTFHSTWVTSEAYSSPSIVLSARGGD 496
            +P ++  K+ DSTYP+KNE+A+G+IL++  FLI YTFH TWVTSEAYSSPSIVLSARGGD
Sbjct: 2425 QPQRQEPKKPDSTYPLKNEIANGVILIITAFLILYTFHCTWVTSEAYSSPSIVLSARGGD 2246

Query: 497  GSRIIFDDFREAYYWLRHNTPEDAKVMSWWDYGYQITAMANRTILVDNNTWNNTHISRVG 556
            GSRIIFDDFREAYYWLRHNTPE++KVMSWWDYGYQITAMANRTILVDNNTWNNTHISRVG
Sbjct: 2245 GSRIIFDDFREAYYWLRHNTPENSKVMSWWDYGYQITAMANRTILVDNNTWNNTHISRVG 2066

Query: 557  QAMASTEEKAYEIM---RELDVSYVLVIFGGLTGYSSDDINKFLWMVRIGGSTETGRHIK 613
            QAMASTEE   +     R+L +S        L         + LWMVRIGGST+ G+HI 
Sbjct: 2065 QAMASTEESVRDNARA*RQLRLSDFWWPHWLLLRRHQ----QVLWMVRIGGSTDRGKHIH 1898

Query: 614  ENDYYTPTGEFRVDREGSPVLLNCLMYKMCYYRFGQVYTEAKRPPGFDRVRNAEIGNKDF 673
            E DYYTP GEFRVDREGSPVLLNCLMYKMCYYRFG VYTE+ +P G+DRVRNAEIGNKDF
Sbjct: 1897 EMDYYTPQGEFRVDREGSPVLLNCLMYKMCYYRFGAVYTESGQPTGYDRVRNAEIGNKDF 1718

Query: 674  ELDVLEEAYTTEHWLVRIYKVKDLDNRGL 702
            ELDVLEEAYTTEHWLVRIYKVKDL+NRG+
Sbjct: 1717 ELDVLEEAYTTEHWLVRIYKVKDLENRGV 1631
>03996
          Length = 1105

 Score = 39.3 bits (90), Expect = 0.006,   Method: Composition-based stats.
 Identities = 17/17 (100%), Positives = 17/17 (100%)
 Frame = -2

Query: 663  VRNAEIGNKDFELDVLE 679
            VRNAEIGNKDFELDVLE
Sbjct: 1104 VRNAEIGNKDFELDVLE 1054
>08629
          Length = 440

 Score = 29.3 bits (64), Expect = 6.3,   Method: Composition-based stats.
 Identities = 11/31 (35%), Positives = 18/31 (58%)
 Frame = -2

Query: 332 SLLDPSYAKNNIPIIASVSEHQPTTWSSYYF 362
           ++L P +A  NIP +   S+  P  W SY++
Sbjct: 328 NMLTP*FACTNIPQVQEYSKKNPPEWVSYHY 236
>02610
          Length = 697

 Score = 28.5 bits (62), Expect = 9.6,   Method: Composition-based stats.
 Identities = 20/85 (23%), Positives = 39/85 (45%), Gaps = 3/85 (3%)
 Frame = +2

Query: 624 FRVDREGSPVLLNCLMYKMCYYR-FGQVYTEAKRPPGFDRVRNAEIGNKDF--ELDVLEE 680
           F ++++   + L C+++ MCY +    V  ++  P  F  V  +    K F  + + L E
Sbjct: 32  FEINKQMRTLHLQCVLFNMCYLQHVRSVCAQSSNPTFFHFVFGSSFTTKFFFKQEN*LNE 211

Query: 681 AYTTEHWLVRIYKVKDLDNRGLSRT 705
            +   H L+    +  L  RG++ T
Sbjct: 212 THANNHHLIISEIMTMLHKRGMATT 286
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|19705578|ref|NP_031535.2| vacuolar H+ATPase B2 [Mus
musculus]
         (511 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

00590                                                                 631   0.0  
37643                                                                  84   2e-16
04005                                                                  65   9e-11
00095                                                                  55   5e-08
16215                                                                  54   2e-07
00880                                                                  49   6e-06
02237                                                                  29   4.5  
34886                                                                  28   8.3  
>00590
          Length = 2486

 Score =  631 bits (1627), Expect = 0.0,   Method: Compositional matrix adjust.
 Identities = 301/331 (90%), Positives = 318/331 (96%), Gaps = 1/331 (0%)
 Frame = +1

Query: 178 DGMNSIARGQKIPIFSAAGLPHNEIAAQICRQAGLVK-KSKDVVDYSEENFAIVFAAMGV 236
           D MNSIARGQKIPIFSAAGLPHNEIAAQICRQ GLVK   K V+D  ++NFAIVFAAMGV
Sbjct: 1   DTMNSIARGQKIPIFSAAGLPHNEIAAQICRQGGLVKLPGKSVLDDHDDNFAIVFAAMGV 180

Query: 237 NMETARFFKSDFEENGSMDNVCLFLNLANDPTIERIITPRLALTTAEFLAYQCEKHVLVI 296
           NME ARFFK DFEENGSM+NVCLFLNLANDPTIERIITPR+ALTTAE++AYQCEKHVLVI
Sbjct: 181 NMEIARFFKQDFEENGSMENVCLFLNLANDPTIERIITPRIALTTAEYMAYQCEKHVLVI 360

Query: 297 LTDMSSYAEALREVSAAREEVPGRRGFPGYMYTDLATIYERAGRVEGRNGSITQIPILTM 356
           LTDMSSYAEALREVSAAREEVPGRRGFPGYMYTDLATIYERAGRVEGRNGSITQIPILTM
Sbjct: 361 LTDMSSYAEALREVSAAREEVPGRRGFPGYMYTDLATIYERAGRVEGRNGSITQIPILTM 540

Query: 357 PNDDITHPIPDLTGYITEGQIYVDRQLHNRQIYPPINVLPSLSRLMKSAIGEGMTRKDHA 416
           PNDDITHPIPDLTGYITEGQIYVDRQLHNRQIYPPINVLPSLSRLMKSAIGEGMTR+DH+
Sbjct: 541 PNDDITHPIPDLTGYITEGQIYVDRQLHNRQIYPPINVLPSLSRLMKSAIGEGMTREDHS 720

Query: 417 DVSNQLYACYAIGKDVQAMKAVVGEEALTSDDLLYLEFLQKFEKNFITQGPYENRTVYET 476
           DVSNQLYACYAIGKDVQAMKAVVGEEALT +DLLYLEFL KFEKNFI+QG YENRT++E+
Sbjct: 721 DVSNQLYACYAIGKDVQAMKAVVGEEALTPEDLLYLEFLTKFEKNFISQGHYENRTIFES 900

Query: 477 LDIGWQLLRIFPKEMLKRIPQSTLSEFYPRD 507
           LDIGWQLLRIFPKEMLKRIPQSTL+++YPRD
Sbjct: 901 LDIGWQLLRIFPKEMLKRIPQSTLAKYYPRD 993
>37643
          Length = 1463

 Score = 83.6 bits (205), Expect = 2e-16,   Method: Compositional matrix adjust.
 Identities = 65/252 (25%), Positives = 113/252 (44%), Gaps = 2/252 (0%)
 Frame = -3

Query: 163  RIYPEEMIQTGISAIDGMNSIARGQKIPIFSAAGLPHNEIAAQICRQAGLVKKSKDVVDY 222
            R   +E +QTGI A+D +  I RGQ+  I          +A        + +K  +  + 
Sbjct: 1410 RTSVKEPMQTGIKAVDSLVPIGRGQRELIIGDRQTGKTAVAVDTI----INQKRLNDGNN 1243

Query: 223  SEENFAIVFAAMGVNMETARFFKSDFEENGSMDNVCLFLNLANDPTIERIITPRLALTTA 282
             ++    ++ A+G    T         +  +M    +    A+D    + + P       
Sbjct: 1242 EKQKLYCIYVAIGQKRSTVAQLVKRLTDADAMKYTIVVSATASDAAPLQYLAPYSGCAMG 1063

Query: 283  EFLAYQCEKHVLVILTDMSSYAEALREVSAAREEVPGRRGFPGYMYTDLATIYERAGRVE 342
            EF       H L+I  D+S  A A R++S      PGR  +PG ++   + + ERA ++ 
Sbjct: 1062 EFF-RDNGMHALIIYDDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKMN 886

Query: 343  GRNG--SITQIPILTMPNDDITHPIPDLTGYITEGQIYVDRQLHNRQIYPPINVLPSLSR 400
              NG  S+T +P++     D++  IP     IT+GQI+++ +L  + I P INV  S+SR
Sbjct: 885  DDNGGGSLTALPVIETQAGDVSAYIPTNVISITDGQIFLETELFYKGIRPAINVGLSVSR 706

Query: 401  LMKSAIGEGMTR 412
            +  +A    M +
Sbjct: 705  VGAAAQTRAMKQ 670
>04005
          Length = 913

 Score = 64.7 bits (156), Expect = 9e-11,   Method: Compositional matrix adjust.
 Identities = 48/185 (25%), Positives = 93/185 (50%), Gaps = 1/185 (0%)
 Frame = +1

Query: 291 KHVLVILTDMSSYAEALREVSAAREEVPGRRGFPGYMYTDLATIYERAGRVEGRNGSITQ 350
           + VL+ + ++  + +A  EVSA    +P   G+   + TD+ T+ ER      + GSIT 
Sbjct: 7   QDVLLFIDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATDMGTMQERITTT--KKGSITS 180

Query: 351 IPILTMPNDDITHPIPDLTGYITEGQIYVDRQLHNRQIYPPINVLPSLSRLMK-SAIGEG 409
           +  + +P DD+T P P  T    +    + R +    IYP ++ L S SR++  + +GE 
Sbjct: 181 VQAIYVPADDLTDPAPATTFAHLDATTVLSRGIAELGIYPAVDPLDSTSRILDPNIVGE- 357

Query: 410 MTRKDHADVSNQLYACYAIGKDVQAMKAVVGEEALTSDDLLYLEFLQKFEKNFITQGPYE 469
                H  ++  +       K +Q + A++G + L+ +D L +   +K ++ F++Q P++
Sbjct: 358 ----HHYKIARAVQKILQDFKSLQDIIAILGMDELSEEDKLTVSRARKMQR-FLSQ-PFQ 519

Query: 470 NRTVY 474
              V+
Sbjct: 520 VAEVF 534
>00095
          Length = 572

 Score = 55.5 bits (132), Expect = 5e-08,   Method: Compositional matrix adjust.
 Identities = 47/171 (27%), Positives = 77/171 (45%), Gaps = 2/171 (1%)
 Frame = -2

Query: 238 METARFFKSDFEENGSMDNVCLFLNLANDPTIERIITPRLALTTAEFLAYQCE--KHVLV 295
           M T+R    D + +     V L     N+P +     PR A  T     ++ E  + VL+
Sbjct: 511 MITSRVISLDDDSS----KVSLVYGQMNEPQVH---VPRGADRTDGGRXFRDEEGQDVLL 353

Query: 296 ILTDMSSYAEALREVSAAREEVPGRRGFPGYMYTDLATIYERAGRVEGRNGSITQIPILT 355
            + ++  + +A  EVSA    +P   G+   + TD+ T+ ER        GSIT +  + 
Sbjct: 352 FIDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATDMGTMQERI--TTTNKGSITSVQAIY 179

Query: 356 MPNDDITHPIPDLTGYITEGQIYVDRQLHNRQIYPPINVLPSLSRLMKSAI 406
           +P DD+T P P  T    +    + R +    IYP ++ L S SR++   I
Sbjct: 178 VPADDLTDPAPATTFAHLDATTVLSRGIAELGIYPAVDPLDSTSRILDPNI 26
>16215
          Length = 1251

 Score = 53.5 bits (127), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 31/88 (35%), Positives = 45/88 (51%)
 Frame = -3

Query: 254 MDNVCLFLNLANDPTIERIITPRLALTTAEFLAYQCEKHVLVILTDMSSYAEALREVSAA 313
           M    L  N +N P   R  +    +T +E+       +V ++    S +AEALRE+S  
Sbjct: 454 MKRTALVANTSNMPVAAREASIYTGITLSEYFR-DMGLNVSMMADSTSRWAEALREISGR 278

Query: 314 REEVPGRRGFPGYMYTDLATIYERAGRV 341
             E+P   G+P Y+   LA+ YERAGRV
Sbjct: 277 LAEMPADSGYPAYLGARLASFYERAGRV 194
>00880
          Length = 2381

 Score = 48.5 bits (114), Expect = 6e-06,   Method: Compositional matrix adjust.
 Identities = 31/76 (40%), Positives = 45/76 (59%), Gaps = 2/76 (2%)
 Frame = -1

Query: 115  TGDILRTPVSEDMLGRVFNGSGKPID-RGPVVLAE-DFLDIMGQPINPQCRIYPEEMIQT 172
            TG I+  PV +D+LGRV +  G PID +GPV   E   + +    I P+  +  +E +QT
Sbjct: 1940 TGAIVDVPVGKDLLGRVVDALGNPIDGKGPVGGGERQRVGVKAPGIIPRTSV--KEPMQT 1767

Query: 173  GISAIDGMNSIARGQK 188
            GI A+D +  I RGQ+
Sbjct: 1766 GIKAVDSLVPIGRGQR 1719
>02237
          Length = 2054

 Score = 28.9 bits (63), Expect = 4.5,   Method: Compositional matrix adjust.
 Identities = 11/23 (47%), Positives = 15/23 (65%)
 Frame = +3

Query: 452  LEFLQKFEKNFITQGPYENRTVY 474
             EFLQ FEK + T GPY  + ++
Sbjct: 1455 FEFLQSFEKKYTTLGPYAGKWLH 1523
>34886
          Length = 777

 Score = 28.1 bits (61), Expect = 8.3,   Method: Compositional matrix adjust.
 Identities = 15/41 (36%), Positives = 23/41 (56%)
 Frame = +3

Query: 359 DDITHPIPDLTGYITEGQIYVDRQLHNRQIYPPINVLPSLS 399
           DDIT  + D  G +  GQ+Y       R  +PP++ LPS++
Sbjct: 489 DDITEDVIDCKGSLV*GQLYE----GGRPTHPPLSGLPSMA 599
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|20149756|ref|NP_619610.1| eukaryotic translation
initiation factor 4A, isoform 3 [Mus musculus]
         (411 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

01062                                                                 736   0.0  
09316                                                                 239   1e-63
07310                                                                 191   4e-49
00621                                                                 188   3e-48
02498                                                                 155   4e-38
00739                                                                 149   3e-36
01517                                                                 146   1e-35
19640                                                                 146   2e-35
02054                                                                 111   2e-34
09327                                                                 130   7e-31
00162                                                                 117   7e-27
34295                                                                 105   3e-23
00617                                                                 104   7e-23
04883                                                                 101   6e-22
31899                                                                  93   2e-19
14337                                                                  91   6e-19
08036                                                                  62   8e-19
11160                                                                  79   4e-18
12995                                                                  81   7e-16
22006                                                                  75   6e-14
19151                                                                  74   1e-13
19525                                                                  74   1e-13
11624                                                                  73   2e-13
10649                                                                  70   2e-12
33025                                                                  69   3e-12
19172                                                                  60   1e-09
39583                                                                  57   1e-08
17708                                                                  56   2e-08
17544                                                                  52   4e-07
33083                                                                  50   1e-06
03381                                                                  48   8e-06
33543                                                                  47   2e-05
31781                                                                  46   3e-05
30136                                                                  45   4e-05
31220                                                                  45   7e-05
06438                                                                  43   2e-04
11423                                                                  41   0.001
12121                                                                  37   0.015
08819                                                                  28   5.4  
>01062
          Length = 2138

 Score =  736 bits (1901), Expect = 0.0,   Method: Compositional matrix adjust.
 Identities = 345/392 (88%), Positives = 372/392 (94%)
 Frame = -3

Query: 20   EEDMTKVEFETSEEVDVTPTFDTMGLREDLLRGIYAYGFEKPSXXXXXXXXXXXXGRDVI 79
            +ED+  VEFETSE+V+VTPTFD MG+RE+LLRGIYAYGFEKPS            GRDVI
Sbjct: 2133 QEDLRAVEFETSEDVEVTPTFDNMGIREELLRGIYAYGFEKPSAIQQRAVKPIVKGRDVI 1954

Query: 80   AQSQSGTGKTATFSVSVLQCLDIQVRETQALILAPTRELAVQIQKGLLALGDYMNVQCHA 139
            AQ+QSGTGKTATFS+SVLQCLDIQ+RETQALIL+PTRELA QIQK +LALGDYMNVQCH+
Sbjct: 1953 AQAQSGTGKTATFSISVLQCLDIQLRETQALILSPTRELATQIQKVMLALGDYMNVQCHS 1774

Query: 140  CIGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEMLNKGFKE 199
            CIGGTN+GEDIRKLDYGQH+V+GTPGRVFDMI+RR+LRTR+IKM++LDEADEMLNKGFKE
Sbjct: 1773 CIGGTNIGEDIRKLDYGQHIVSGTPGRVFDMIKRRNLRTRSIKMMILDEADEMLNKGFKE 1594

Query: 200  QIYDVYRYLPPATQVVLISATLPHEILEMTNKFMTDPIRILVKRDELTLEGIKQFFVAVE 259
            QIYDVYRYLPPATQV+LISATLPHEILEMTNKFMTDPIRILVKRDELTLEGIKQFFVAVE
Sbjct: 1593 QIYDVYRYLPPATQVILISATLPHEILEMTNKFMTDPIRILVKRDELTLEGIKQFFVAVE 1414

Query: 260  REEWKFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERESI 319
            REEWKFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERE+I
Sbjct: 1413 REEWKFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKEREAI 1234

Query: 320  MKEFRSGASRVLISTDVWARGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAIN 379
            MK FR+G SRVLI+TDVWARG+DV QVSL+INYDLPNNRELYIHRIGRSGR+GRKGVAIN
Sbjct: 1233 MKVFRAGDSRVLITTDVWARGIDVQQVSLVINYDLPNNRELYIHRIGRSGRFGRKGVAIN 1054

Query: 380  FVKNDDIRILRDIEQYYSTQIDEMPMNVADLI 411
            FVKNDDIRILRDIEQYYSTQIDEMPMNVADLI
Sbjct: 1053 FVKNDDIRILRDIEQYYSTQIDEMPMNVADLI 958
>09316
          Length = 2312

 Score =  239 bits (611), Expect = 1e-63,   Method: Compositional matrix adjust.
 Identities = 132/370 (35%), Positives = 212/370 (57%), Gaps = 5/370 (1%)
 Frame = +2

Query: 40   FDTMGLREDLLRGIYAYGFEKPSXXXXXXXXXXXXGRDVIAQSQSGTGKTATFSVSVLQC 99
            F    L+ +LLR I   GFE PS              DV+ Q++SG GKTA F ++ LQ 
Sbjct: 851  FRDFLLKPELLRAIIDCGFEHPSEVQHECIPQAILSMDVLCQAKSGMGKTAVFVLATLQQ 1030

Query: 100  LDIQVRETQALILAPTRELAVQIQKGLLALGDYMN-VQCHACIGGTNVGEDIRKLDYG-Q 157
            L+    +   L++A TRELA QI K       YMN V+     GG +V +D   L     
Sbjct: 1031 LEPVDGQVSVLVMAHTRELAFQISKEYERFSKYMNNVKIAVFFGGMSVKKDEEVLSKNCP 1210

Query: 158  HVVAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEML-NKGFKEQIYDVYRYLPPATQVVL 216
            H+V GTPGR+  + +  +L  + IK  +LDE D+ML +   +  + +++R  P   QV++
Sbjct: 1211 HIVVGTPGRLHALAKANNLNLKKIKHFILDECDKMLADLDMRRDVQEIFRLTPHEKQVMM 1390

Query: 217  ISATLPHEILEMTNKFMTDPIRILVKRD-ELTLEGIKQFFVAVEREEWKFDTLCDLYDTL 275
             SATL  EI  +  KFM DP+ + V  D +LTL G++Q +  ++  E K   L +L D L
Sbjct: 1391 FSATLSKEIRPICKKFMQDPMEVYVDDDSKLTLHGLQQHYCKLKDNE-KNRKLFELLDVL 1567

Query: 276  TITQAVIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTD 335
               Q +IF  +  +   L++ + E NF   ++H  M Q+ER S  ++F+    R+L++T+
Sbjct: 1568 EFNQVIIFVKSVPRCMALSQLLLEQNFPAIAIHRQMTQEERLSRYQQFKDFQKRILVATN 1747

Query: 336  VWARGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAINFVKN-DDIRILRDIEQ 394
            ++ RG+D+ +V+++ NYD+P + + Y+HR+ R+GR+G KG+AI FV + +D +IL D+++
Sbjct: 1748 LFGRGMDIERVNIVFNYDMPEDSDTYLHRVARAGRFGTKGLAITFVSDENDAKILNDVQE 1927

Query: 395  YYSTQIDEMP 404
             +   I E+P
Sbjct: 1928 RFEVNITELP 1957
>07310
          Length = 712

 Score =  191 bits (486), Expect = 4e-49,   Method: Compositional matrix adjust.
 Identities = 90/239 (37%), Positives = 151/239 (63%)
 Frame = +2

Query: 166 RVFDMIRRRSLRTRAIKMLVLDEADEMLNKGFKEQIYDVYRYLPPATQVVLISATLPHEI 225
           R+ D++ +R ++     +LVLDEAD++L++ FK  + ++  +LPP  Q++L SAT P  +
Sbjct: 2   RILDLMNKRLVKPDTCGILVLDEADKLLSQDFKGMLDNIIAHLPPQRQILLYSATFPLSV 181

Query: 226 LEMTNKFMTDPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCN 285
            +   K++ +P  I +  +ELTL+G+ Q++  V+ E+ K   L  L+  L I Q++IFCN
Sbjct: 182 EQFMKKYLKNPYEINL-MEELTLKGVTQYYAFVQ-EKQKVHCLNTLFSKLQINQSIIFCN 355

Query: 286 TKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQ 345
           + ++V+ L +K+ E  ++   +H  M Q+ R  +  +FR G  R L+ +D++ RG+D+  
Sbjct: 356 STQRVELLAKKITELGYSCYYIHAKMNQQHRNRVFHDFRQGLCRNLVCSDLFTRGIDIQA 535

Query: 346 VSLIINYDLPNNRELYIHRIGRSGRYGRKGVAINFVKNDDIRILRDIEQYYSTQIDEMP 404
           V+++IN+D P + E Y+HRIGRSGRYG  GVAIN +  +D   L  IEQ   T+I  +P
Sbjct: 536 VNVVINFDFPKHAETYLHRIGRSGRYGHLGVAINLITFEDRFSLHKIEQELGTEIKPIP 712
>00621
          Length = 2263

 Score =  188 bits (478), Expect = 3e-48,   Method: Compositional matrix adjust.
 Identities = 114/400 (28%), Positives = 200/400 (50%), Gaps = 35/400 (8%)
 Frame = +1

Query: 45  LREDLLRGIYAYGFEKPSXXXXXXXXXXXXGRDVIAQSQSGTGKTATFSVSVL------- 97
           L  D++  I   G+++P+             RD+I  +++G+GKTA F + +L       
Sbjct: 274 LGADIMEVIDRVGYKEPTPIQMQAIPIGLQNRDIIGVAETGSGKTAAFLIPLLVWIQSLP 453

Query: 98  --QCLDIQVRETQALILAPTRELAVQIQKGLLALGDYMNVQCHACIGGTNVGEDIRKLDY 155
             + L+   +   A+ILAPTRELA QI++     G+ + ++  + IGG +  E   KL  
Sbjct: 454 KIERLEDADQGPYAVILAPTRELAQQIEEETRKFGEGLGIRVVSVIGGISREEQGFKLQQ 633

Query: 156 GQHVVAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEMLNKGFKEQIYDVYRYLPPATQ-- 213
           G  VV  TPGR+ D++  R L       +V+DEAD M+N GF+ ++  +  YLP + Q  
Sbjct: 634 GCEVVIATPGRMIDVLENRYLVLNQCTYVVMDEADRMINMGFEPEVRKILDYLPVSNQKP 813

Query: 214 -----------------------VVLISATLPHEILEMTNKFMTDPIRILVKRDELTLEG 250
                                   V+ +AT+P ++  +   F+  P  + +      +E 
Sbjct: 814 DNDDAEDDLKMLQNFKSKHKYRQTVMFTATMPPQVERLARTFLRRPTVVYIGNVGKPVER 993

Query: 251 IKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKMREANFTVSSMHGD 310
           ++Q    +   E K   L ++ +       +IF N K+  D L + + +  F  +++HG 
Sbjct: 994 VEQIVYMLTESE-KRKKLIEVLNAGVDPPIIIFVNQKKGADVLAKSLEKMGFNATTLHGG 1170

Query: 311 MPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLIINYDLPNNRELYIHRIGRSGR 370
             Q++RE  +   + GA  ++++TDV  RG+D+  VSL++NYD+    E Y HRIGR+GR
Sbjct: 1171KGQEQREYALASLKGGAKDIMVATDVAGRGIDIKDVSLVLNYDMARTIEDYTHRIGRTGR 1350

Query: 371 YGRKGVAINFVKNDDIRILRDIEQY-YSTQIDEMPMNVAD 409
            G++G +I F+  +D  +  D++Q   S+ +   P  +A+
Sbjct: 1351AGKEGTSITFLTKEDSMVFYDLKQLMLSSPVSTCPPELAN 1470
>02498
          Length = 1955

 Score =  155 bits (391), Expect = 4e-38,   Method: Compositional matrix adjust.
 Identities = 75/207 (36%), Positives = 131/207 (63%), Gaps = 7/207 (3%)
 Frame = +3

Query: 204 VYRYLPPATQVVLISATLPHEILEMTNKFMTDPIRILVKRDELTLEGIKQFFVAVEREEW 263
           V+R+L P+   V  SA  P            DP+ I +KR+E +L+ IKQ+++    +E 
Sbjct: 675 VFRHLRPSGDAVC-SAHHPQ-----------DPVIISLKREEESLDNIKQYYIDCNSQEE 818

Query: 264 KFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEF 323
           K+  LC++Y ++++ Q++IFC+ +    WL E+M   +  V  + G++  ++R +I+K F
Sbjct: 819 KYVALCNIYGSISVGQSMIFCHKRSTAAWLAERMTADHHAVGLLTGELTIEQRAAIIKRF 998

Query: 324 RSGASRVLISTDVWARGLDVPQVSLIINYDLPNNR------ELYIHRIGRSGRYGRKGVA 377
           R G  +VLI+T+V ARG+DV  V++++N+DLP  +      E Y+HRIGR+GR+G+ G+A
Sbjct: 999 REGKEKVLITTNVSARGIDVEMVTVVVNFDLPVTQDWRPDCETYLHRIGRTGRFGKNGIA 1178

Query: 378 INFVKND-DIRILRDIEQYYSTQIDEM 403
           IN V N   + I+R IE+++  +I+++
Sbjct: 1179INMVDNSRSMAIMRSIEKHFGRKIEKL 1259

 Score = 98.6 bits (244), Expect = 4e-21,   Method: Compositional matrix adjust.
 Identities = 66/200 (33%), Positives = 105/200 (52%), Gaps = 5/200 (2%)
 Frame = +1

Query: 39  TFDTMGLREDLLRGIYAYGFEKPSXXXXXXXXXXXXGRDV--IAQSQSGTGKTATFSVSV 96
           +F+ + L+  LL+G+Y  GF  PS               V  IAQSQSGTGKTA F +++
Sbjct: 136 SFEALNLKPQLLKGVYDMGFNAPSKIQETALPILLADPPVNMIAQSQSGTGKTAAFVLTM 315

Query: 97  LQCLDIQVRETQALILAPTRELAVQIQKGLLALGDYMN-VQCHACIGGTNVGEDIRKLDY 155
           L  +DI     Q L LAPT ELA+QI + +  +  +M  ++    + G  V    R    
Sbjct: 316 LSRVDISQTFPQCLCLAPTYELALQIGEVIEKMSKHMTGLEIRYAVRGERVN---RGEVL 486

Query: 156 GQHVVAGTPGRVFDMIRR-RSLRTRAIKMLVLDEADEMLN-KGFKEQIYDVYRYLPPATQ 213
            + +V GTPG V D   R ++L    +++ VLDEAD M++ +G ++Q   + + L    Q
Sbjct: 487 SEQIVIGTPGTVMDWSHRFKALPLEKLRVFVLDEADVMISMQGHQDQSTRIQKRLSSGCQ 666

Query: 214 VVLISATLPHEILEMTNKFM 233
           ++L SAT    +++   + +
Sbjct: 667 MLLFSATYDQVVMQFAQRII 726
>00739
          Length = 1313

 Score =  149 bits (375), Expect = 3e-36,   Method: Compositional matrix adjust.
 Identities = 84/263 (31%), Positives = 144/263 (54%), Gaps = 4/263 (1%)
 Frame = +3

Query: 147 GEDIRKLDYGQHVVAGTPGRVFDMIRR-RSLRTRAIKMLVLDEADEMLNKGFKEQIYDVY 205
           G+D   L    H+V  TPGR+ D I    +   + +K LV+DEAD +L+  F  Q+  + 
Sbjct: 21  GQD---LAVKPHIVISTPGRLADHIDSCDTFSLKRVKFLVMDEADRLLDDNFGAQLEPIL 191

Query: 206 RYLPPATQVVLISATLPHEILEMTNKFMTDPIRILVKRDELTLEGIKQFFVAVE---REE 262
             LP A Q +L SATL   +  + +  +  P   + + +  T++ +++ +V V    ++ 
Sbjct: 192 TRLPSARQTLLFSATLSPTVNALRDSVLNKPFVWIQQSERATVDELQEDYVLVPASMKDA 371

Query: 263 WKFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKE 322
           +    L         +  +IF  T +    L   + +  F+ + +H  +PQ+ R S +  
Sbjct: 372 YMVHILDHWLKDHPRSSLIIFTXTCKYAQILGMMLEKLQFSCAVLHSMIPQRFRLSSLSR 551

Query: 323 FRSGASRVLISTDVWARGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAINFVK 382
           F+S  +R+LISTDV +RGLD+P V LIIN+++PN    Y+HR+GR+ R GR G +I+ V 
Sbjct: 552 FKSNQTRILISTDVASRGLDIPTVDLIINHNIPNRPRDYVHRVGRTARAGRCGQSISLVT 731

Query: 383 NDDIRILRDIEQYYSTQIDEMPM 405
             DI++++ IE + + Q+ E P+
Sbjct: 732 EFDIKLIKSIESHINCQMTEHPV 800
>01517
          Length = 2605

 Score =  146 bits (369), Expect = 1e-35,   Method: Compositional matrix adjust.
 Identities = 91/243 (37%), Positives = 134/243 (55%), Gaps = 7/243 (2%)
 Frame = +2

Query: 169 DMIRRRSLRTRAIKMLVLDEADEMLNKGFKEQIYDVYR--YLPPATQ--VVLISATLPHE 224
           DM+ R  +       LVLDEAD ML+ GF+ QI  +     +PP  Q   ++ SAT P E
Sbjct: 5   DMMERGKIGMDHCNYLVLDEADRMLDMGFEPQIRRIVEKDTMPPTGQRQTLMFSATFPKE 184

Query: 225 ILEMTNKFMTDPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLY---DTLTITQAV 281
           I  +   F+ + I + V R   T E I Q  V VE  E K   L DL     T   +  +
Sbjct: 185 IQLLARDFLDNYIFLAVGRVGSTSENITQKVVWVEEPE-KRSFLLDLLMASGTGPESLTL 361

Query: 282 IFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGL 341
           +F  TK+  D L + +   N+  +S+HGD  Q+ERE  ++ F++G   +L++T V ARGL
Sbjct: 362 VFVETKKGADSLEQFLMYENYPATSIHGDRSQREREDALRVFKNGDRPILVATAVAARGL 541

Query: 342 DVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAINFVKNDDIRILRDIEQYYSTQID 401
           D+P V  +IN+DLP++ E Y+HRIGR+GR G  G+A +F  + +  I RD+    +    
Sbjct: 542 DIPNVRHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNDKNRNIARDMLDLLTEANQ 721

Query: 402 EMP 404
           E+P
Sbjct: 722 EVP 730
>19640
          Length = 456

 Score =  146 bits (368), Expect = 2e-35,   Method: Compositional matrix adjust.
 Identities = 65/88 (73%), Positives = 78/88 (88%)
 Frame = -1

Query: 282 IFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGL 341
           IFCNT+RKVD LT++M   NFTVS+MHGDM Q++RE IMK+FRSG+SRVLI+TD+ ARG+
Sbjct: 456 IFCNTRRKVDQLTQEMSSHNFTVSAMHGDMEQRDREVIMKQFRSGSSRVLITTDLLARGI 277

Query: 342 DVPQVSLIINYDLPNNRELYIHRIGRSG 369
           DV QVSL+INYDLP+NRE YIHRIGR G
Sbjct: 276 DVQQVSLVINYDLPSNRENYIHRIGRGG 193

 Score = 68.9 bits (167), Expect = 3e-12,   Method: Compositional matrix adjust.
 Identities = 36/55 (65%), Positives = 43/55 (78%), Gaps = 1/55 (1%)
 Frame = -3

Query: 358 RELYIHRIGRS-GRYGRKGVAINFVKNDDIRILRDIEQYYSTQIDEMPMNVADLI 411
           REL  H   RS  R+GRKGVAINF+ +DD RIL+DIEQ+Y T I+EMP N+ADLI
Sbjct: 226 REL--HS*NRSRWRFGRKGVAINFITDDDRRILKDIEQFYHTTIEEMPANIADLI 68
>02054
          Length = 1110

 Score =  111 bits (277), Expect(2) = 2e-34,   Method: Compositional matrix adjust.
 Identities = 53/172 (30%), Positives = 96/172 (55%)
 Frame = -3

Query: 233 MTDPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCNTKRKVDW 292
           + DP+++ V     T++ ++Q ++ +   ++K   L  + + L     ++FC+T      
Sbjct: 769 LRDPVKVEVSNKYQTVDTLQQSYLFIP-AKYKDAYLVSILNELAGNSFMVFCSTCANTQR 593

Query: 293 LTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLIINY 352
           +   +R   FT   +HG M Q +R   + +F+S    +LI+TDV +RGLD+P V +++N 
Sbjct: 592 VALLLRNLGFTAIPLHGQMSQAKRLGSLNKFKSKDRSILIATDVASRGLDIPHVDVVLNL 413

Query: 353 DLPNNRELYIHRIGRSGRYGRKGVAINFVKNDDIRILRDIEQYYSTQIDEMP 404
           D+P + + Y+HR+GR+ R GR G AI FV   D+ + + IE     ++ E P
Sbjct: 412 DIPTHSKDYMHRVGRTARAGRSGRAITFVSQYDVELYQRIEHLIGKKLSEYP 257

 Score = 52.8 bits (125), Expect(2) = 2e-34,   Method: Compositional matrix adjust.
 Identities = 24/80 (30%), Positives = 45/80 (56%), Gaps = 1/80 (1%)
 Frame = -2

Query: 158 HVVAGTPGRVFDMIRR-RSLRTRAIKMLVLDEADEMLNKGFKEQIYDVYRYLPPATQVVL 216
           H++  TPGR+ D +   +    RA+K LV+DEAD +L+  F++++  + + +P      L
Sbjct: 998 HIIIATPGRLVDHLENTKGFSLRALKFLVMDEADRILDMNFQDEVDKILKVIPRERNTYL 819

Query: 217 ISATLPHEILEMTNKFMTDP 236
            SAT+ +++ + T      P
Sbjct: 818 FSATMTNKVAKTTASITEGP 759
>09327
          Length = 1087

 Score =  130 bits (328), Expect = 7e-31,   Method: Compositional matrix adjust.
 Identities = 78/234 (33%), Positives = 123/234 (52%), Gaps = 3/234 (1%)
 Frame = +2

Query: 111 ILAPTRELAVQIQKGLLALGDYMNVQCHACIGGTNVGEDIRKLDYGQHVVAGTPGRVFDM 170
           +L PTRELA Q+Q+  +  G    V+     GG   G  +R+LD G  +   TPGR+ D 
Sbjct: 20  LLVPTRELAQQVQEVAVEFGHSSRVRSVCVYGGAQRGPQLRELDRGAEICIATPGRLIDF 199

Query: 171 IRRRSLRTRAIKMLVLDEADEMLNKGFKEQIYDVYRYLPPATQVVLISATLPHEILEMTN 230
           +       R    LVLDEAD ML+ GF+ QI  +   + P  Q ++ SAT P E+ ++  
Sbjct: 200 LESNRTNLRRCTYLVLDEADRMLDMGFEPQIRKIVEQIRPDRQTLMWSATWPKEVRKLAE 379

Query: 231 KFMTDPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTI---TQAVIFCNTK 287
            F+ +  +I +   +LT        + V  +  K + L  L + +      + +IF  TK
Sbjct: 380 DFIMEYTQINIGALQLTANHNILQIIDVCMDHEKEEKLVKLLNEIMQEKENRTLIFVETK 559

Query: 288 RKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGL 341
           RK D +  +M+   + V  +HGD  Q+ER+ ++ +FR+G   VL++TDV +RGL
Sbjct: 560 RKCDDIHRRMKRDGWPVLCIHGDKSQQERDWVLNDFRNGRCPVLLATDVASRGL 721
>00162
          Length = 2322

 Score =  117 bits (294), Expect = 7e-27,   Method: Compositional matrix adjust.
 Identities = 83/277 (29%), Positives = 138/277 (49%), Gaps = 6/277 (2%)
 Frame = +3

Query: 108 QALILAPTRELAVQIQKGLLALGDYMNVQCHACIGGTNVGEDIRKLDYGQHVVAGTPGRV 167
           +ALI+ PTRELA QI + L  +  + +   +  IGG  +  +   +    ++V  T GR+
Sbjct: 141 EALIITPTRELAFQIYEVLNKIRTFHDFSANLVIGGKFMWRETHLMG-KTNIVICTVGRL 317

Query: 168 FDMIRR-RSLRTRAIKMLVLDEADEMLNKGFKEQIYDVYRYLPPATQVVLISATLPHEIL 226
              +   ++     +K+LVLDEAD +++  F + +  +  +LPP  Q +L SAT    + 
Sbjct: 318 LHHLESTQAFDVSELKVLVLDEADRIMDSKFAQDMDSIMSHLPP-RQTLLFSATQTMSVK 494

Query: 227 EMTNKFMTDPIRILVKR--DELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIF- 283
            +    + DP  + V R  + +T  G++Q ++  E  E K   L          + ++F 
Sbjct: 495 TLARLSLKDPSYVSVDRHAEYVTPTGLEQSYIVCELHE-KLSLLYSFLKNHPNNKIMVFL 671

Query: 284 --CNTKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGL 341
             C   R V  + ++ R    +V  +HG +PQ  R  I +EF      +LI+TD+  RGL
Sbjct: 672 QTCKQARYVHTVIKRERPG-MSVLVLHGGIPQLRRLDIYREFCRKQHVILITTDLACRGL 848

Query: 342 DVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAI 378
           D P V+ +I  D P +   YIHR GR+ R+   G A+
Sbjct: 849 DFPAVNWVIQLDCPVDVNTYIHRAGRTARFECNGQAL 959
>34295
          Length = 694

 Score =  105 bits (263), Expect = 3e-23,   Method: Compositional matrix adjust.
 Identities = 56/131 (42%), Positives = 80/131 (61%), Gaps = 1/131 (0%)
 Frame = -1

Query: 277 ITQAVIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDV 336
           I   +IF NTK+    L+  +         +HG M QKER S +  F+S   R LI+TDV
Sbjct: 544 IPNVMIFTNTKKYCQLLSMTLTNMEIENVCLHGFMRQKERVSALSRFKSNHIRTLIATDV 365

Query: 337 WARGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAINFVK-NDDIRILRDIEQY 395
            ARGLD+P V L+IN+ LP   + YIHR+GR+ R GRKGVAI+  +   D+ +L  IE+ 
Sbjct: 364 AARGLDIPSVQLVINHMLPRTPKEYIHRVGRTARAGRKGVAISIFRFPRDLELLGAIEEE 185

Query: 396 YSTQIDEMPMN 406
            +T++ E P++
Sbjct: 184 INTKLTEHPID 152
>00617
          Length = 1505

 Score =  104 bits (259), Expect = 7e-23,   Method: Compositional matrix adjust.
 Identities = 45/110 (40%), Positives = 75/110 (68%)
 Frame = -3

Query: 302  FTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLIINYDLPNNRELY 361
            F+ + +H  +PQ+ R S +  F+S  +R+LISTDV +RGLD+P V LIIN+++PN    Y
Sbjct: 1482 FSCAVLHSMIPQRFRLSSLSRFKSNQTRILISTDVASRGLDIPTVDLIINHNIPNRPRDY 1303

Query: 362  IHRIGRSGRYGRKGVAINFVKNDDIRILRDIEQYYSTQIDEMPMNVADLI 411
            +HR+GR+ R GR G +I+ V   DI++++ IE + + Q+ E P+   +++
Sbjct: 1302 VHRVGRTARAGRCGQSISLVTEFDIKLIKSIESHINCQMTEHPVKEKEVL 1153
>04883
          Length = 1155

 Score =  101 bits (251), Expect = 6e-22,   Method: Compositional matrix adjust.
 Identities = 70/260 (26%), Positives = 118/260 (45%), Gaps = 8/260 (3%)
 Frame = +3

Query: 39  TFDTMGLREDLLRGIYAYGFEKPSXXXXXXXXXXXXGRDVIAQSQSGTGKTATFSVSVLQ 98
           TF  +   + ++  +    +  P+            G+D++  +Q+G+GKT  F +  + 
Sbjct: 363 TFTEVNFPDYVMNQVRRNSWTAPTPIQSQSWPVAMAGKDLVGIAQTGSGKTLAFMLPAIV 542

Query: 99  CLDIQV---RETQALILA--PTRELAVQIQKGLLALGDYMNVQCHACIGGTNVGEDIRKL 153
            ++ Q    R    ++LA  PTRELA Q+Q+     G    V+     GG   G  +R L
Sbjct: 543 HINHQAYLERGDGPIVLALVPTRELAQQVQEVAQEFGHASRVRSVCVYGGAPRGPQLRDL 722

Query: 154 DYGQHVVAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEMLNKGFKEQIYDVYRYLPPATQ 213
           + G  +   TPGR+ D +       R    LVLDEAD ML+ GF+ QI  +   + P  Q
Sbjct: 723 ERGAEICIATPGRLIDFLESNRTNLRRCTYLVLDEADRMLDMGFEPQIRKIIEQIRPDRQ 902

Query: 214 VVLISATLPHEILEMTNKFMTDPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYD 273
            ++ SAT P E+ ++   F+ + +++ +   ELT        + V  E  K D L  L +
Sbjct: 903 TLMWSATWPKEVRKLAEDFIDEYVQVNIGALELTANHNILQIIDVCMEHEKEDKLVKLLN 1082

Query: 274 TLTITQAVI---FCNTKRKV 290
            +   +      FC  + K+
Sbjct: 1083EIMTRKKRTKPSFCGDQEKM 1142
>31899
          Length = 453

 Score = 93.2 bits (230), Expect = 2e-19,   Method: Compositional matrix adjust.
 Identities = 52/121 (42%), Positives = 73/121 (60%), Gaps = 1/121 (0%)
 Frame = -1

Query: 30  TSEEVDVTPTFDTMGLREDLLRGIYAYGFEKPSXXXXXXXXXXXXGRDVIAQSQSGTGKT 89
           TSE VD    F ++ L + +L G+   GFE+PS            G D+I Q++SGTGKT
Sbjct: 357 TSESVD----FASLLLSKPVLNGLKNAGFERPSPIQLKAIPLGRCGLDLIVQAKSGTGKT 190

Query: 90  ATFSVSVLQCLDIQVRETQALILAPTRELAVQIQKGLLALGDYMN-VQCHACIGGTNVGE 148
             FSV  L+ ++   R TQ L+LAPTRE+A+QI + + ++G  M+ +QCH  IGG  V E
Sbjct: 189 CVFSVVALEGIETTARSTQVLVLAPTREIALQIWEVINSIGSAMSGLQCHTFIGGLPVHE 10

Query: 149 D 149
           D
Sbjct: 9   D 7
>14337
          Length = 693

 Score = 91.3 bits (225), Expect = 6e-19,   Method: Compositional matrix adjust.
 Identities = 48/144 (33%), Positives = 73/144 (50%)
 Frame = +2

Query: 261 EEWKFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERESIM 320
           E  K   + +L+        ++F  +K++   L  +       V ++H D PQ ER++ +
Sbjct: 8   EAGKLMAMRNLFTEGITPPVLVFVQSKQRAKELYSEFMFDKHKVDAIHADKPQAERDATV 187

Query: 321 KEFRSGASRVLISTDVWARGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAINF 380
           + F  G   VL+ T++  RG+D   ++L+INYD P N   YIHRIGR+GR G  G AI F
Sbjct: 188 RAFTEGRVWVLVCTELMGRGIDFKGINLVINYDFPTNAVSYIHRIGRTGRAGVPGRAITF 367

Query: 381 VKNDDIRILRDIEQYYSTQIDEMP 404
               D+  LR I         E+P
Sbjct: 368 FTEQDVTHLRSIANIIKEAGCEVP 439
>08036
          Length = 1226

 Score = 61.6 bits (148), Expect(2) = 8e-19,   Method: Compositional matrix adjust.
 Identities = 43/178 (24%), Positives = 85/178 (47%), Gaps = 2/178 (1%)
 Frame = +1

Query: 160 VAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEMLNKGFKEQIYDVYRYLPPATQVVLISA 219
           V GTP R+   +R   L    ++MLV+DEAD + + G +  +  +   LP   Q  L+SA
Sbjct: 1   VVGTPSRILAHLRAGHLELHTVQMLVVDEADLVFSFGHEADMKKLMEELPRIYQAFLMSA 180

Query: 220 TLPHEILEMTNKFMTDPIRILVKRDELTLEG-IKQFFVAVEREEWKFDTLCDLYDT-LTI 277
           TL  ++  +    + +P+ + +K  +L     + Q+ V  E ++ KF  +  +    L  
Sbjct: 181 TLSEDVKALKKMVLHNPVILKLKESQLPESTQLTQYHVKCEVDD-KFTLMVAVLKLGLVR 357

Query: 278 TQAVIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTD 335
            ++++F N+      L   +         ++ ++P K R  I+ +F  G   ++I++D
Sbjct: 358 GKSILFVNSVDSCYKLKLFLEPFGIPACVLNSELPVKSRCHIVSQFNEGLYDIIIASD 531

 Score = 50.1 bits (118), Expect(2) = 8e-19,   Method: Compositional matrix adjust.
 Identities = 21/64 (32%), Positives = 36/64 (56%)
 Frame = +3

Query: 338 ARGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAINFVKNDDIRILRDIEQYYS 397
           ARG+D   VS +IN++ P   + YIHR+GR+ R  ++G A++ +   +      +E+   
Sbjct: 612 ARGIDFQNVSNVINFEFPKTVDAYIHRVGRTARGDKQGCALSLISRHENDQFEAVEEAQK 791

Query: 398 TQID 401
           T  D
Sbjct: 792 TDKD 803
>11160
          Length = 646

 Score = 78.6 bits (192), Expect(2) = 4e-18,   Method: Compositional matrix adjust.
 Identities = 55/189 (29%), Positives = 94/189 (49%), Gaps = 16/189 (8%)
 Frame = -1

Query: 142 GGTNVGEDIRK-LDYGQHVVAGTPGRVFDMIRRR------SLRTRAIKMLVLDEADEMLN 194
           GG +   DI K +  G  ++  TPGR+ D+  R+      +   +A+++LVLDEAD +L+
Sbjct: 646 GGVSCSHDISKFMKSGGSILIATPGRLDDLFSRKESGFNLAASVKALEVLVLDEADRLLD 467

Query: 195 KGFKEQIYDVYRYLPPATQVVLISATLPHEILEMTNKFMTDPIRILVKRDELTLEG---- 250
            GF+  I  +  +LP   +  L SAT   E+  +    + +P+R+ VK  +L  E     
Sbjct: 466 MGFEASINTILGHLPKLRRTGLFSATQTDEVENLIRAGLRNPLRVTVKEKKLAGEADQRT 287

Query: 251 ---IKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKMRE--ANFTVS 305
              +  +++ VE EE KF  L     T    + ++F +T   VD+ +  + +   +  V 
Sbjct: 286 PSTLSNYYMIVEAEE-KFSQLVKFLKTHHRDKLLLFFSTCACVDYFSMCLTQLLKHMQVL 110

Query: 306 SMHGDMPQK 314
           S+H  M QK
Sbjct: 109 SIHSKMKQK 83

 Score = 30.4 bits (67), Expect(2) = 4e-18,   Method: Compositional matrix adjust.
 Identities = 13/30 (43%), Positives = 20/30 (66%)
 Frame = -3

Query: 313 QKERESIMKEFRSGASRVLISTDVWARGLD 342
           + E + +  +FRS  S +L+ TDV ARG+D
Sbjct: 92  EAEEKPVFAKFRSITSGLLVCTDVMARGVD 3
>12995
          Length = 1072

 Score = 81.3 bits (199), Expect = 7e-16,   Method: Compositional matrix adjust.
 Identities = 35/126 (27%), Positives = 68/126 (53%)
 Frame = +3

Query: 281 VIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARG 340
           V+F  TK  V++L   + +     + ++  + Q  R+  + +F     +V++ TD+ ARG
Sbjct: 141 VVFVATKHHVEYLNTLLTKCGIACTYIYSSLDQTARKIHVAKFTHKQVKVMLVTDLAARG 320

Query: 341 LDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAINFVKNDDIRILRDIEQYYSTQI 400
           +D+PQ+  ++N+  P   +L++HR+GR  R GR G A + V  D++  L D+  +    +
Sbjct: 321 IDIPQLDNVVNFHFPAKAKLFVHRVGRVARAGRSGTAYSLVAMDEVAHLVDLHVFLGRPL 500

Query: 401 DEMPMN 406
              P +
Sbjct: 501 KTAPQS 518
>22006
          Length = 3414

 Score = 74.7 bits (182), Expect = 6e-14,   Method: Compositional matrix adjust.
 Identities = 38/121 (31%), Positives = 69/121 (57%), Gaps = 1/121 (0%)
 Frame = +2

Query: 75   GRDVIAQSQSGTGKTATFSVSVLQCLDIQV-RETQALILAPTRELAVQIQKGLLALGDYM 133
            G+D++A +++G+GKTA F V +L+ L +   +  +ALIL+PTRELA+Q  K    LG ++
Sbjct: 3047 GKDMVAMARTGSGKTAAFLVPMLERLKMHSSKGARALILSPTRELALQTLKFTKELGKFL 3226

Query: 134  NVQCHACIGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEML 193
            +++    +GG  + +    L     ++  TPGR+  ++       + +  +V DEAD + 
Sbjct: 3227 DLRAAVILGGDRMEDQFSALHQNPDIIIATPGRLLHVLVEMKKSLKEVIYVVFDEADRLF 3406

Query: 194  N 194
             
Sbjct: 3407 E 3409
>19151
          Length = 625

 Score = 73.9 bits (180), Expect = 1e-13,   Method: Compositional matrix adjust.
 Identities = 34/88 (38%), Positives = 60/88 (68%), Gaps = 7/88 (7%)
 Frame = -3

Query: 329 RVLISTDVWARGLDVPQVSLIINYDLP------NNRELYIHRIGRSGRYGRKGVAINFVK 382
           +VLI+T+V +RG+D+ QV++++N+DLP       + E Y+HRIGR+GR+G+ G+AIN + 
Sbjct: 623 KVLITTNVLSRGIDIEQVTIVVNFDLPIDLRGNADCETYLHRIGRTGRFGKSGIAINLID 444

Query: 383 ND-DIRILRDIEQYYSTQIDEMPMNVAD 409
            +  + + R IE+++   I  +  + AD
Sbjct: 443 GEKSMNVCRAIEKHFQKDIVYLNTDNAD 360
>19525
          Length = 585

 Score = 73.6 bits (179), Expect = 1e-13,   Method: Compositional matrix adjust.
 Identities = 48/161 (29%), Positives = 84/161 (52%), Gaps = 1/161 (0%)
 Frame = +2

Query: 107 TQALILAPTRELAVQIQKGLLALGDYMNVQCHACIGGTNVGEDIRKLDYGQHVVAGTPGR 166
           T+ L+L PTRELAVQ+ +    +  Y  +      GG ++      L     +V  TPGR
Sbjct: 14  TRVLVLVPTRELAVQVYQVGQQISQYTKISICLAAGGLDIKGQEAALRLCPDIVVATPGR 193

Query: 167 VFDMIRRRSLRTRA-IKMLVLDEADEMLNKGFKEQIYDVYRYLPPATQVVLISATLPHEI 225
           + D +      T A +++LVLDEAD ML++ F  Q+ ++ R      Q +L SAT+   +
Sbjct: 194 LIDHLHNAPNFTIAHVEILVLDEADRMLDEYFAAQMTEIIRMCNFQRQTMLFSATMSDAV 373

Query: 226 LEMTNKFMTDPIRILVKRDELTLEGIKQFFVAVEREEWKFD 266
            ++ +  + + +++ V ++     G++Q FV + RE  + D
Sbjct: 374 QDLASVSLKEAVKVFVNQNTDIALGLQQEFVRI-RENKEGD 493
>11624
          Length = 2257

 Score = 73.2 bits (178), Expect = 2e-13,   Method: Compositional matrix adjust.
 Identities = 42/141 (29%), Positives = 71/141 (50%), Gaps = 1/141 (0%)
 Frame = -1

Query: 247 TLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKMR-EANFTVS 305
           T EG+ ++ V  +  E     L  L++ L     + F N+      L   ++     +V 
Sbjct: 991 TPEGLTEYIVESDSSEKPLLVLHFLHN-LKFRSVLCFTNSVETTHRLCLLVKLYGGLSVK 815

Query: 306 SMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLIINYDLPNNRELYIHRI 365
                +P + R+ I+K+F  G   +L+ +D  ARG+DV  V  +I+YD P   + YIHR+
Sbjct: 814 EFSSRLPGERRKKILKQFSKGKIDLLVCSDAMARGMDVDNVKYVISYDNPPYIKTYIHRV 635

Query: 366 GRSGRYGRKGVAINFVKNDDI 386
           GR+ R GR G AI+ ++  + 
Sbjct: 634 GRTARAGRAGTAISLLEKKEF 572

 Score = 54.7 bits (130), Expect = 6e-08,   Method: Compositional matrix adjust.
 Identities = 42/139 (30%), Positives = 68/139 (48%), Gaps = 21/139 (15%)
 Frame = -3

Query: 76   RDVIAQSQSGTGKTATFSVSVLQCLDIQ-VRETQALILAPTRELAVQIQKGLLALGDYMN 134
            RD+   + +G+GKT  +++ ++QCL  + V   +A+I+ P R+LA Q+ +          
Sbjct: 1814 RDICVSAPTGSGKTLAYTLPIIQCLKQRMVPHVRAVIVLPVRDLAEQVYQ---------- 1665

Query: 135  VQCHAC----------IGGT--NVGED-IRKLDYGQ------HVVAGTPGRVFDMIRRR- 174
            V CH C          +G T  NV +D + K  YG        ++  TPGR+ D I    
Sbjct: 1664 VFCHYCADTPLKVGIVVGKTVFNVEQDTLVKKRYGGVYHSVIDILVATPGRLVDHINSTP 1485

Query: 175  SLRTRAIKMLVLDEADEML 193
                  ++ LV+DEAD M+
Sbjct: 1484 GFDLSHLRFLVIDEADRMM 1428
>10649
          Length = 472

 Score = 69.7 bits (169), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 33/85 (38%), Positives = 49/85 (57%)
 Frame = +1

Query: 294 TEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLIINYD 353
           +++ R A  +V  +HG +PQ  R  I +EF      +LI+TD+  RGLD P V+ +I  D
Sbjct: 43  SDQARAAGMSVLVLHGGIPQLRRLDIYREFCRKQHVILITTDLACRGLDFPAVNWVIQLD 222

Query: 354 LPNNRELYIHRIGRSGRYGRKGVAI 378
            P +   YIHR GR+ R+   G A+
Sbjct: 223 CPVDVNTYIHRAGRTARFECNGQAL 297
>33025
          Length = 558

 Score = 68.9 bits (167), Expect = 3e-12,   Method: Compositional matrix adjust.
 Identities = 42/133 (31%), Positives = 71/133 (53%), Gaps = 4/133 (3%)
 Frame = +3

Query: 156 GQHVVAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEMLNKGFKEQIYDVY--RYLPPAT- 212
           G ++V GTPGR+ D I  +++     + L+LDEAD ML+ GF+ +I  +     +PP T 
Sbjct: 105 GANLVVGTPGRLLDFIGDQTISLGKCQYLILDEADRMLDMGFEPEIRKLVDTHGMPPKTQ 284

Query: 213 -QVVLISATLPHEILEMTNKFMTDPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDL 271
            Q ++ SAT   +I  +   F+ D + I V         + Q F+ V+R + K D LC++
Sbjct: 285 RQTLMFSATFKEDIQRLAGDFLNDYLFITVGIVGGACSDVTQTFLEVDRLQ-KRDHLCEI 461

Query: 272 YDTLTITQAVIFC 284
            + +   ++V  C
Sbjct: 462 LNEMGTAKSVGVC 500
>19172
          Length = 484

 Score = 60.1 bits (144), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 25/64 (39%), Positives = 42/64 (65%)
 Frame = -1

Query: 278 TQAVIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVW 337
           T+ +IF  TK++VD +T  +    +   ++HGD  Q+ER+ ++  FR+G   +L++TDV 
Sbjct: 334 TKTIIFVETKKRVDEITRNISRQGWRACAIHGDKSQQERDFVLSSFRNGRHSILVATDVA 155

Query: 338 ARGL 341
           ARGL
Sbjct: 154 ARGL 143
>39583
          Length = 234

 Score = 57.0 bits (136), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 26/70 (37%), Positives = 42/70 (60%)
 Frame = -3

Query: 303 TVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLIINYDLPNNRELYI 362
           TV S        +R   +K F+ G   VL++TD+ +RGLD+  V  +IN+ +P+  + Y+
Sbjct: 211 TVESCMATCR*AQRLEALKRFKEGEIDVLLATDLASRGLDIEGVKTVINFTMPSTLKHYV 32

Query: 363 HRIGRSGRYG 372
           HR+GR+ R G
Sbjct: 31  HRVGRTARAG 2
>17708
          Length = 882

 Score = 56.2 bits (134), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 31/101 (30%), Positives = 57/101 (56%), Gaps = 4/101 (3%)
 Frame = +1

Query: 76  RDVIAQSQSGTGKTATFSVSVLQC---LDIQVRE-TQALILAPTRELAVQIQKGLLALGD 131
           RD++  +++G+GKT  F +  ++    L    R  T  +I++PTREL++Q    L  L  
Sbjct: 553 RDLMGAAKTGSGKTLAFLIPAIELMYKLKFMPRNGTGCIIISPTRELSMQTFNVLTELLK 732

Query: 132 YMNVQCHACIGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIR 172
           Y +      +GG N  ++++KL  G +++  TPGR+ D ++
Sbjct: 733 YHHHTFGLIMGGVNRHDEVKKLKKGVNIIVATPGRLLDHLQ 855
>17544
          Length = 1047

 Score = 52.4 bits (124), Expect = 4e-07,   Method: Compositional matrix adjust.
 Identities = 44/162 (27%), Positives = 69/162 (42%), Gaps = 27/162 (16%)
 Frame = +2

Query: 24  TKVEFETSEEVDVTPT----------FDTMGLREDLLRGIYAYGFEKPSXXXXXXXXXXX 73
           T + F+  E++ V  T          F+   L E +   I    + KP+           
Sbjct: 560 TGINFDKYEDIPVEATGDSPPPHINSFEECTLGEIIRNNIVLSKYNKPTPVQKFALPIVL 739

Query: 74  XGRDVIAQSQSGTGKTATFSVSVLQCL--------DIQVRETQ---------ALILAPTR 116
             RD++A +Q+G+GKTA F + +L  +         +Q  +++         ALILAPTR
Sbjct: 740 GKRDLMACAQTGSGKTAAFLLPILNQVYENGPTPEALQQNQSRGYRRKMYPIALILAPTR 919

Query: 117 ELAVQIQKGLLALGDYMNVQCHACIGGTNVGEDIRKLDYGQH 158
           ELA QI            ++     GG ++G  +R LD G H
Sbjct: 920 ELASQIYDEARKFAYRSRLRPCVVYGGADIGAQMRDLDKGCH 1045
>33083
          Length = 1931

 Score = 50.4 bits (119), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 25/69 (36%), Positives = 41/69 (59%), Gaps = 1/69 (1%)
 Frame = +1

Query: 339 RGLDVPQVSLIINYDLPNNRELYIHRIGRSGR-YGRKGVAINFVKNDDIRILRDIEQYYS 397
           RGLD+PQV  I+ YD P+  + YIHR+GR+ R  G  G A+  ++ +++  L+ +     
Sbjct: 1   RGLDIPQVDWIVQYDPPDESKEYIHRVGRTARGEGSSGKALLLLQPEELGFLKFLRA-AK 177

Query: 398 TQIDEMPMN 406
            ++ EM  N
Sbjct: 178 VKVQEMDFN 204
>03381
          Length = 1206

 Score = 47.8 bits (112), Expect = 8e-06,   Method: Compositional matrix adjust.
 Identities = 17/45 (37%), Positives = 29/45 (64%)
 Frame = +3

Query: 341 LDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAINFVKNDD 385
           LD+P +  ++NYD+  + + + HR+GR+GR G KG A   + + D
Sbjct: 3   LDIPHIRTVVNYDVARDIDTHTHRVGRTGRAGEKGSAYTLITDKD 137
>33543
          Length = 471

 Score = 47.0 bits (110), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 16/49 (32%), Positives = 34/49 (69%), Gaps = 1/49 (2%)
 Frame = +3

Query: 361 YIHRIGRSGRYGRKGVAINFVKND-DIRILRDIEQYYSTQIDEMPMNVA 408
           Y+HR+GR+GR+G +G+AI FV N+ +  +L  +++ +   + ++P  ++
Sbjct: 6   YLHRVGRAGRFGTRGLAITFVSNETEADVLNSVQERFEVSVTDLPEQIS 152
>31781
          Length = 416

 Score = 45.8 bits (107), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 15/50 (30%), Positives = 35/50 (70%)
 Frame = -2

Query: 235 DPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFC 284
           +P+ I ++R+E +L+ I+Q+++       K+  LC++Y ++++ Q++IFC
Sbjct: 277 NPVTIRLRREEESLDNIQQYYIRCRTLSDKYRALCNIYGSISVGQSMIFC 128
>30136
          Length = 524

 Score = 45.4 bits (106), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 34/129 (26%), Positives = 58/129 (44%), Gaps = 5/129 (3%)
 Frame = +2

Query: 40  FDTMGLREDLLRGIYAYGFEKPSXXXXXXXXXXXXGRDVIAQSQSGTGKTATFSVSVLQC 99
           F    L + +++ I   G++ P+            G + +  +++G+GKT  + +  +  
Sbjct: 137 FAEAYLPDYVIKEIRRQGYKSPTPIQAQGWPIAMSGANFVGIAKTGSGKTLGYILPAIVH 316

Query: 100 LDIQVRETQ-----ALILAPTRELAVQIQKGLLALGDYMNVQCHACIGGTNVGEDIRKLD 154
           ++ Q    +     AL+LAPTRELA QIQ+     G    V+     GG   G  +R L 
Sbjct: 317 INNQQPLQRGEGPIALVLAPTRELAQQIQQVATEFGSSSYVRNTCVFGGAPKGGQMRDLQ 496

Query: 155 YGQHVVAGT 163
            G  +V  T
Sbjct: 497 RGCEIVIAT 523
>31220
          Length = 818

 Score = 44.7 bits (104), Expect = 7e-05,   Method: Compositional matrix adjust.
 Identities = 27/92 (29%), Positives = 45/92 (48%)
 Frame = +2

Query: 314 KERESIMKEFRSGASRVLISTDVWARGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGR 373
           K+R+S   +  S ASR          G+D   V+ +IN+D P +   YIHR GR+ R   
Sbjct: 122 KQRKSKHTDHESSASR----------GIDFQGVNNVINFDFPLDVTSYIHRAGRTARGNN 271

Query: 374 KGVAINFVKNDDIRILRDIEQYYSTQIDEMPM 405
            G  ++FV   ++ I + +E+   +     P+
Sbjct: 272 TGSVLSFVSVKELPINQAVEEKLRSCFGREPL 367
>06438
          Length = 989

 Score = 43.1 bits (100), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 18/47 (38%), Positives = 27/47 (57%)
 Frame = +1

Query: 332 ISTDVWARGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAI 378
           ++  +  RGLD P V+ +I  D P +   YIHR GR+ R+   G A+
Sbjct: 25  LTVTLACRGLDFPAVNWVIQLDCPVDVNTYIHRAGRTARFECNGQAL 165
>11423
          Length = 1434

 Score = 40.8 bits (94), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 22/70 (31%), Positives = 39/70 (55%), Gaps = 4/70 (5%)
 Frame = -2

Query: 345  QVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAINFVKNDDI----RILRDIEQYYSTQI 400
            Q   +I+YD P   + YIHR+GR+ R GR G AI+ ++  +     +++R+  ++   +I
Sbjct: 1403 QRKYVISYDNPPYIKTYIHRVGRTARAGRAGTAISLLEKKEFFHFKQMMREAGKW--KKI 1230

Query: 401  DEMPMNVADL 410
             EM +    L
Sbjct: 1229 KEMKLGRQAL 1200
>12121
          Length = 465

 Score = 37.0 bits (84), Expect = 0.015,   Method: Compositional matrix adjust.
 Identities = 17/39 (43%), Positives = 21/39 (53%)
 Frame = -3

Query: 159 VVAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEMLNKGF 197
           +   TPGR+ D +       R    LVLDEAD ML+ GF
Sbjct: 463 ICIATPGRLIDFLESNRTNLRRCTYLVLDEADRMLDMGF 347
>08819
          Length = 597

 Score = 28.5 bits (62), Expect = 5.4,   Method: Compositional matrix adjust.
 Identities = 14/38 (36%), Positives = 23/38 (60%)
 Frame = +3

Query: 223 HEILEMTNKFMTDPIRILVKRDELTLEGIKQFFVAVER 260
           H  +++ +K  T  I ++VKR++  L  +KQF V VE 
Sbjct: 336 HLFVQINDKSFTPQIYLMVKRNKQVL*FVKQFVVTVEH 449
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|21450277|ref|NP_659149.1| Na+/K+ -ATPase alpha 1
subunit [Mus musculus]
         (1023 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

00499                                                                1074   0.0  
14773                                                                 379   e-105
06342                                                                 313   3e-85
28890                                                                 288   6e-78
08160                                                                 208   7e-54
36566                                                                 120   2e-27
03937                                                                 118   1e-26
12151                                                                  88   3e-25
33697                                                                  76   7e-23
17925                                                                  90   4e-18
29829                                                                  70   4e-12
13525                                                                  68   2e-11
04985                                                                  59   1e-08
14321                                                                  49   8e-06
21541                                                                  40   2e-04
07486                                                                  38   0.021
05368                                                                  33   0.85 
17101                                                                  31   2.9  
23730                                                                  29   9.2  
>00499
          Length = 4026

 Score = 1074 bits (2777), Expect = 0.0,   Method: Compositional matrix adjust.
 Identities = 510/675 (75%), Positives = 583/675 (86%)
 Frame = +2

Query: 349  KRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTENQSG 408
            KRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFD +I EADT+++QS 
Sbjct: 44   KRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDGRIVEADTSDDQSN 223

Query: 409  VSFDKTSATWFALSRIAGLCNRAVFQANQENLPILKRAVAGDASESALLKCIEVCCGSVM 468
             ++ ++  TW ALSR+A LCNRA F+ NQ+N+PILKR   GDASESALLKC+E+  G V 
Sbjct: 224  ATYSRSDPTWMALSRVAMLCNRAEFKGNQDNVPILKRECNGDASESALLKCVELSIGHVT 403

Query: 469  EMREKYSKIVEIPFNSTNKYQLSIHKNPNASEPKHLLVMKGAPERILDRCSSILLHGKEQ 528
            E R +  KIVEIPFNS+NKYQ+SIH+  +  +P++LLVMKGAPERI+DRCS+ILL+GKEQ
Sbjct: 404  EYRRRNEKIVEIPFNSSNKYQVSIHETEDPDDPRYLLVMKGAPERIMDRCSTILLNGKEQ 583

Query: 529  PLDEELKDAFQNAYXXXXXXXXXXXXFCHLLLPDEQFPEGFQFDTDDVNFPVDNLCFVGL 588
            PLD+  ++AF  AY            FC   LP +QFP G++FD +  NFP+  L FVGL
Sbjct: 584  PLDDNFREAFNAAYLELGGLGERVLGFCDYFLPVDQFPPGYEFDPEGPNFPITGLRFVGL 763

Query: 589  ISMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARL 648
            ++MIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIA+GVGIISEG++TVEDIA+  
Sbjct: 764  MAMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIARGVGIISEGSKTVEDIASER 943

Query: 649  NIPVNQVNPRDAKACVVHGSDLKDMTSEELDDILRYHTEIVFARTSPQQKLIIVEGCQRQ 708
             IPV +V+PR+AKA V+HG DL+DMT  ++D+ILR H+EIVFARTSPQQKLIIVEGCQRQ
Sbjct: 944  GIPVEEVDPREAKAAVIHGGDLRDMTPAQIDEILRNHSEIVFARTSPQQKLIIVEGCQRQ 1123

Query: 709  GAIVAVTGDGVNDSPALKKADIGVAMGIVGSDVSKQAADMILLDDNFASIVTGVEEGRLI 768
            G IVAVTGDGVNDSPALKKADIGVAMGI GSDVSKQAADMILLDDNFASIVTGVEEGRLI
Sbjct: 1124 GQIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILLDDNFASIVTGVEEGRLI 1303

Query: 769  FDNLKKSIAYTLTSNIPEITPFLIFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEQAE 828
            FDNLKKSIAYTLTSNIPEI+PFL+FI+A+IPLPLGT+TILCIDLGTDMVPAISLAYE+AE
Sbjct: 1304 FDNLKKSIAYTLTSNIPEISPFLLFILADIPLPLGTITILCIDLGTDMVPAISLAYEKAE 1483

Query: 829  SDIMKRQPRNPKTDKLVNERLISMAYGQIGMIQALGGFFTYFVILAENGFLPFHLLGIRE 888
            +DIMKRQPR+P  DKLVNERLISMAYGQIGMIQA  GFFTYFVI+ ENGF    LLGIR 
Sbjct: 1484 NDIMKRQPRDPVKDKLVNERLISMAYGQIGMIQASAGFFTYFVIMGENGFWYDRLLGIRM 1663

Query: 889  TWDDRWVNDVEDSYGQQWTYEQRKIVEFTCHTAFFVSIVVVQWADLVICKTRRNSVFQQG 948
             WD R VND+EDSYGQ+WTY QRK +E+TCHTAFFVSIV+VQWAD++ICKTRR S+FQQG
Sbjct: 1664 EWDSRGVNDLEDSYGQEWTYSQRKKLEYTCHTAFFVSIVIVQWADIIICKTRRLSLFQQG 1843

Query: 949  MKNKILIFGLFEETALAAFLSYCPGMGAALRMYPLKPTWWFCAFPYSLLIFVYDEVRKLI 1008
            MKNK LIFG+F ETALAAFL YCPG+   LRMYPL+ TWWF A P+SL IF+YDE RKLI
Sbjct: 1844 MKNKHLIFGIFFETALAAFLCYCPGLDKGLRMYPLRLTWWFTAVPFSLTIFIYDECRKLI 2023

Query: 1009 IRRRPGGWVEKETYY 1023
            +RR PGG+VE+ETYY
Sbjct: 2024 LRRNPGGFVERETYY 2068
>14773
          Length = 794

 Score =  379 bits (973), Expect = e-105,   Method: Compositional matrix adjust.
 Identities = 180/265 (67%), Positives = 214/265 (80%)
 Frame = +2

Query: 739  SDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLIFIIANI 798
            SDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEI+PFL++I+   
Sbjct: 2    SDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEISPFLVYILFGT 181

Query: 799  PLPLGTVTILCIDLGTDMVPAISLAYEQAESDIMKRQPRNPKTDKLVNERLISMAYGQIG 858
            PLPLG +TIL IDLGTDMVPAISLAYE AESDIMKR PR   +D+LVNERLI+M+YGQIG
Sbjct: 182  PLPLGVITILFIDLGTDMVPAISLAYEMAESDIMKRPPRT-ISDRLVNERLIAMSYGQIG 358

Query: 859  MIQALGGFFTYFVILAENGFLPFHLLGIRETWDDRWVNDVEDSYGQQWTYEQRKIVEFTC 918
            M+QAL GF+ + ++  ++GF+   L GIR  WD   +ND+EDSYGQ WT  QR  VE + 
Sbjct: 359  MMQALAGFYAWILVFGQSGFMVRDLPGIRSFWDSANINDLEDSYGQNWTKAQRMDVELSG 538

Query: 919  HTAFFVSIVVVQWADLVICKTRRNSVFQQGMKNKILIFGLFEETALAAFLSYCPGMGAAL 978
            +T FF++IV+VQW+D++ICKTRR SVF QGM N +L FG+F ET+LA  LSY PG+  AL
Sbjct: 539  YTVFFITIVLVQWSDIIICKTRRLSVFHQGMSNHVLTFGIFFETSLAVLLSYTPGVDVAL 718

Query: 979  RMYPLKPTWWFCAFPYSLLIFVYDE 1003
            R  PL+  WW  A P+ +LIFVYDE
Sbjct: 719  RTRPLRFEWWLAAIPFQVLIFVYDE 793
>06342
          Length = 2428

 Score =  313 bits (801), Expect = 3e-85,   Method: Compositional matrix adjust.
 Identities = 229/720 (31%), Positives = 365/720 (50%), Gaps = 64/720 (8%)
 Frame = +2

Query: 185 VVVGDLVEVKGGDRIPADLRI--ISANGCKVDNSSLTGESEPQTRS----PDFTNENPLE 238
           +V GD+VEV  GD++PAD+RI  I +   ++D + LTGES    +     PD    N  +
Sbjct: 5   LVPGDIVEVSVGDKVPADIRILKIHSTTLRIDQAILTGESVSVMKHTDPIPDPRAVNQ-D 181

Query: 239 TRNIAFFSTNCVEGTARGIVVYTGDRTVMGRIATLASGLEGGQTPIAEEIEHFIHLITGV 298
            +N+ F  TN   G  +G+V+ TG  T +G+I       E  +TP+ ++++ F + ++ V
Sbjct: 182 KKNLLFSGTNVAAGKCKGLVIGTGLTTEIGKIRNEMMDTEQEKTPLQQKLDEFSNQLSKV 361

Query: 299 AVFLGVSFFILSL------ILEYTWLEAVIFLIGIIVANV----PEGXXXXXXXXXXXXX 348
              + ++ + +++          +W++  I+   I VA      PEG             
Sbjct: 362 ITIICIAVWAINIGHFNDPAHGGSWIKGAIYYFKIAVALAVAAIPEGLPAVITTCLALGT 541

Query: 349 KRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTENQSG 408
           +RMA+KN +V++L +VETLG TS ICSDKTGTLT N+M+V  ++  +QI   DT + ++ 
Sbjct: 542 RRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCKLFIFSQI---DTNQIKT- 709

Query: 409 VSFDKTSATWFA---------------------LSRIAGLCNRAVFQANQENLPILKRAV 447
             F+ T +T+                       L  I G+CN +    N+      K   
Sbjct: 710 TQFEVTGSTYAPDGELYQNGKKVKASDYPGLEELCTICGMCNDSSVDYNEAKTQYEK--- 880

Query: 448 AGDASESALLKCIE-------------------VCCGSVMEMREKYSKIVEIPFNSTNKY 488
            G+A+E+AL    E                   VC   + +M   + K   + F S ++ 
Sbjct: 881 VGEATETALTVLAEKLNFYNTDKSSLNKREMGTVCNHVIQDM---WRKEFTLEF-SRDRK 1048

Query: 489 QLSIHKNPNASEPKHL-----LVMKGAPERILDRCSSILLHGKEQPLDEELKDAFQNAYX 543
            +S+   PN  +P  +     +  KGAPE +LDRC+ + +   + P+   +K+       
Sbjct: 1049SMSVFCVPN--KPTRVPGGARMFAKGAPEGLLDRCTHVRIGNNKVPMSPAIKNEIMK--L 1216

Query: 544 XXXXXXXXXXXFCHLLLPDEQFPEGFQFDTDDVNFPVD---NLCFVGLISMIDPPRAAVP 600
                       C  L   +  P     D +D    ++   N+ FVG++ M+DPPR  V 
Sbjct: 1217TKIYGTGRDTLRCLALATIDNPPRREDMDLEDSRKFIEYETNMTFVGVVGMLDPPREEVM 1396

Query: 601 DAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPVNQVNPRDA 660
            ++  CR+AGI+VI++TGD+  TA+AI + +G+ SE +E  E +A       +++ P D 
Sbjct: 1397ASIKNCRAAGIRVIVITGDNKATAEAICRRIGVFSE-SENTEGLA-YTGREFDELPPEDQ 1570

Query: 661 KACVVHGSDLKDMTSEELDDILRYHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVN 720
           +A V+                       +FAR  P  K  IVE  Q +G I A+TGDGVN
Sbjct: 1571RAAVMRAR--------------------LFARVEPAHKSKIVEYLQAEGEISAMTGDGVN 1690

Query: 721 DSPALKKADIGVAMGIVGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTL 780
           D+PALKKA+IG+AMG  G+ V+K A++M+L DDNF++IV  VEEGR I++N+K+ I Y +
Sbjct: 1691DAPALKKAEIGIAMG-SGTAVAKSASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLI 1867

Query: 781 TSNIPEITPFLIFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEQAESDIMKRQPRNPK 840
           +SNI E+    +     IP  L  V +L ++L TD  PA +L +   + DIM++ PRNP+
Sbjct: 1868SSNIGEVVCIFLTAALGIPEALIPVQLLWVNLVTDGFPATALGFNPPDLDIMQKPPRNPR 2047
>28890
          Length = 552

 Score =  288 bits (738), Expect = 6e-78,   Method: Compositional matrix adjust.
 Identities = 138/183 (75%), Positives = 162/183 (88%)
 Frame = -3

Query: 142 ITGCFSYYQEAKSSKIMESFKNMVPQQALVIRNGEKMSINAEDVVVGDLVEVKGGDRIPA 201
           +TG FSYYQEAKSSKIM+SFKN+VPQ A+V+R  +K+S+ AE++VVGD+VE K GDR+PA
Sbjct: 550 VTGVFSYYQEAKSSKIMDSFKNLVPQFAVVVRGDQKLSVKAEELVVGDIVECKFGDRVPA 371

Query: 202 DLRIISANGCKVDNSSLTGESEPQTRSPDFTNENPLETRNIAFFSTNCVEGTARGIVVYT 261
           DLR+ISA+G KVDNSSLTGESEPQ+RS +FT+ENPLETRNI FFSTN VEGT RGIV+ T
Sbjct: 370 DLRVISAHGFKVDNSSLTGESEPQSRSAEFTHENPLETRNICFFSTNAVEGTCRGIVIKT 191

Query: 262 GDRTVMGRIATLASGLEGGQTPIAEEIEHFIHLITGVAVFLGVSFFILSLILEYTWLEAV 321
           GD TVMGRIA LASGLE G TPIA+EI HFIH+ITGVAVFLGVSFF+++ IL Y WL+AV
Sbjct: 190 GDDTVMGRIANLASGLEVGDTPIAKEIAHFIHIITGVAVFLGVSFFVIAFILGYFWLDAV 11

Query: 322 IFL 324
           IFL
Sbjct: 10  IFL 2
>08160
          Length = 459

 Score =  208 bits (530), Expect = 7e-54,   Method: Compositional matrix adjust.
 Identities = 98/138 (71%), Positives = 114/138 (82%)
 Frame = +2

Query: 349 KRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTENQSG 408
           KRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFD +I EADT+++QS 
Sbjct: 44  KRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDGRIVEADTSDDQSN 223

Query: 409 VSFDKTSATWFALSRIAGLCNRAVFQANQENLPILKRAVAGDASESALLKCIEVCCGSVM 468
            ++ +T  TW AL+R+  LCNRA F+ NQ+N+PILKR   GDASESALLK +E+  G V 
Sbjct: 224 ATYSRTDVTWMALARVGMLCNRAEFKGNQDNVPILKRECNGDASESALLKAVELSIGQVT 403

Query: 469 EMREKYSKIVEIPFNSTN 486
           E R +  KIVEIPFNS+N
Sbjct: 404 EYRRRNKKIVEIPFNSSN 457
>36566
          Length = 589

 Score =  120 bits (302), Expect = 2e-27,   Method: Compositional matrix adjust.
 Identities = 60/146 (41%), Positives = 99/146 (67%)
 Frame = +3

Query: 705 CQRQGAIVAVTGDGVNDSPALKKADIGVAMGIVGSDVSKQAADMILLDDNFASIVTGVEE 764
            Q+ G +V +TGDGVND+ ALK A+IG++MG+ G+DVSK+A+DMIL+DD+F +I+  +EE
Sbjct: 108 LQQNGLVVGMTGDGVNDAVALKSAEIGISMGVSGTDVSKEASDMILVDDDFTTILNAIEE 287

Query: 765 GRLIFDNLKKSIAYTLTSNIPEITPFLIFIIANIPLPLGTVTILCIDLGTDMVPAISLAY 824
           G+ IF N++  + + L+++I  ++   +  +  +P PL  + IL I++  D  PA SL  
Sbjct: 288 GKGIFYNIRNFVRFQLSTSIAALSLIAVSTLLRLPNPLNAMQILWINIIMDGPPAQSLGV 467

Query: 825 EQAESDIMKRQPRNPKTDKLVNERLI 850
           E  + D++K+ PR+   D ++  RLI
Sbjct: 468 EPVDHDVIKQPPRH-VGDPIITRRLI 542
>03937
          Length = 1558

 Score =  118 bits (295), Expect = 1e-26,   Method: Composition-based stats.
 Identities = 51/78 (65%), Positives = 58/78 (74%)
 Frame = -2

Query: 946  QQGMKNKILIFGLFEETALAAFLSYCPGMGAALRMYPLKPTWWFCAFPYSLLIFVYDEVR 1005
            QQGMKNK LIF  F       FL YCPG+   LRMYPL+ TWWF A P+SL IF+YDE R
Sbjct: 1557 QQGMKNKHLIFDXFF*DGAGRFLCYCPGLDKGLRMYPLRLTWWFTAVPFSLTIFIYDECR 1378

Query: 1006 KLIIRRRPGGWVEKETYY 1023
            KLI+RR PGG+VE+ETYY
Sbjct: 1377 KLILRRXPGGFVERETYY 1324
>12151
          Length = 880

 Score = 88.2 bits (217), Expect(2) = 3e-25,   Method: Compositional matrix adjust.
 Identities = 57/169 (33%), Positives = 93/169 (55%)
 Frame = +3

Query: 726 KKADIGVAMGIVGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIP 785
           +KAD+G AMGI G+DV+K+A+D+IL DDNF SIV  V  GR ++D++ K + + LT N+ 
Sbjct: 288 QKADVGFAMGISGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSIAKFLQFQLTVNVV 467

Query: 786 EITPFLIFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEQAESDIMKRQPRNPKTDKLV 845
            +    +   +    PL  + +L ++L  D + +++LA E   S+++KR+P   +T  L+
Sbjct: 468 AVFVAFVGACSIGDSPLKAIQMLWVNLIMDTLASLALATELPSSELLKRRPYG-RTKPLI 644

Query: 846 NERLISMAYGQIGMIQALGGFFTYFVILAENGFLPFHLLGIRETWDDRW 894
           ++ +     G          F+   VIL     L F   G +  WD RW
Sbjct: 645 SKTMWKNILGH--------AFYQILVIL----LLLFQ--GAKAVWDRRW 749

 Score = 46.6 bits (109), Expect(2) = 3e-25,   Method: Compositional matrix adjust.
 Identities = 38/114 (33%), Positives = 58/114 (50%), Gaps = 5/114 (4%)
 Frame = +1

Query: 619 DHPITAKAIAKGVGIISEGNETVEDIAARLNIPVNQVNPRDAKACVVHGSDLKDMTSEEL 678
           D+  TA++IA   GII  G++ +       N  +     RDA+          +++ E++
Sbjct: 1   DNVNTARSIASKCGIIQPGDDGLVLEGKEFNQLI-----RDAEG---------EISQEKV 138

Query: 679 DDILRYHTEIVFARTSPQQKLIIVE-----GCQRQGAIVAVTGDGVNDSPALKK 727
           D++  +    V AR+SPQ K I+V+            +VAVTGDG ND PALKK
Sbjct: 139 DEV--WPNLRVLARSSPQDKYILVKHIIDSKVSTSREVVAVTGDGTNDGPALKK 294
>33697
          Length = 310

 Score = 76.3 bits (186), Expect(3) = 7e-23,   Method: Composition-based stats.
 Identities = 34/37 (91%), Positives = 36/37 (97%)
 Frame = -2

Query: 590 SMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKA 626
           SMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPIT++ 
Sbjct: 204 SMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITSQG 94

 Score = 48.5 bits (114), Expect(3) = 7e-23,   Method: Compositional matrix adjust.
 Identities = 24/33 (72%), Positives = 28/33 (84%)
 Frame = -3

Query: 624 AKAIAKGVGIISEGNETVEDIAARLNIPVNQVN 656
           AKAIAKGVGIISEG+ TVEDI+A   IPV +V+
Sbjct: 101 AKAIAKGVGIISEGSRTVEDISAERGIPVEEVD 3

 Score = 21.6 bits (44), Expect(3) = 7e-23,   Method: Composition-based stats.
 Identities = 8/13 (61%), Positives = 10/13 (76%)
 Frame = -1

Query: 577 NFPVDNLCFVGLI 589
           NFP+  L FVGL+
Sbjct: 244 NFPITGLRFVGLM 206
>17925
          Length = 510

 Score = 90.1 bits (222), Expect = 4e-18,   Method: Compositional matrix adjust.
 Identities = 42/60 (70%), Positives = 51/60 (85%)
 Frame = +3

Query: 658 RDAKACVVHGSDLKDMTSEELDDILRYHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGD 717
           R+A+A V+HG DLK+M ++++DDIL    EIVFARTSPQQKLIIVEGCQR G IVAVTG+
Sbjct: 315 REAEAIVIHGGDLKNMDAKDIDDILHNFVEIVFARTSPQQKLIIVEGCQRNGQIVAVTGE 494
>29829
          Length = 465

 Score = 70.5 bits (171), Expect = 4e-12,   Method: Compositional matrix adjust.
 Identities = 42/127 (33%), Positives = 76/127 (59%)
 Frame = -3

Query: 730 IGVAMGIVGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITP 789
           +G AMGI G+DV+K+A+D+IL DDNF SIV  V  GR ++D++ K + + LT N+  +  
Sbjct: 460 LGFAMGISGTDVAKEASDIILTDDNFTSIVKAVXWGRNVYDSIAKFLQFQLTVNVVAVFV 281

Query: 790 FLIFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEQAESDIMKRQPRNPKTDKLVNERL 849
             +   +    PL  + +L ++L  D + +++LA E   ++++KR+P   +T  L+++ +
Sbjct: 280 AFVGACSIGDSPLEAIQMLWVNLIMDTLASLALATELPSNELLKRKPYG-RTKPLISKTM 104

Query: 850 ISMAYGQ 856
                G 
Sbjct: 103 FKNIAGH 83
>13525
          Length = 645

 Score = 67.8 bits (164), Expect = 2e-11,   Method: Composition-based stats.
 Identities = 31/31 (100%), Positives = 31/31 (100%)
 Frame = +2

Query: 349 KRMARKNCLVKNLEAVETLGSTSTICSDKTG 379
           KRMARKNCLVKNLEAVETLGSTSTICSDKTG
Sbjct: 11  KRMARKNCLVKNLEAVETLGSTSTICSDKTG 103
>04985
          Length = 1671

 Score = 58.5 bits (140), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 44/152 (28%), Positives = 65/152 (42%), Gaps = 4/152 (2%)
 Frame = -1

Query: 689  VFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIVGSDVSKQAADM 748
            VFAR +P QK  ++E  Q    IV + GDG ND  ALK A  G+++    + V+      
Sbjct: 1608 VFARMAPDQKCALIENLQSYDYIVGMCGDGANDCEALKAAHAGISLSEAEASVAAPFTSR 1429

Query: 749  ILLDDNFASIVTGVEEGRLI----FDNLKKSIAYTLTSNIPEITPFLIFIIANIPLPLGT 804
            I   +N   +VT + EGR      F   K    Y+    I       + I+      L  
Sbjct: 1428 I---NNIECVVTAMREGRAALVTSFGCFKYMALYSFIQFIS------VLILYTCQTNLSD 1276

Query: 805  VTILCIDLGTDMVPAISLAYEQAESDIMKRQP 836
            +  L IDL      A+ L Y  A   +++ +P
Sbjct: 1275 LEFLYIDLIITTTIAVLLGYTGAYDKLVRHKP 1180
>14321
          Length = 568

 Score = 49.3 bits (116), Expect = 8e-06,   Method: Compositional matrix adjust.
 Identities = 38/135 (28%), Positives = 64/135 (47%), Gaps = 19/135 (14%)
 Frame = +2

Query: 619 DHPITAKAIAKGVGIISEGNETVEDIAARLNIP----------VNQVNPRDAKACVVHGS 668
           D+P+TA  +AK + +  +    +     RL+               ++P   +  ++   
Sbjct: 2   DNPLTACHVAKELRMTRKDKTLILTPPNRLDSDWHWQSIDDSVTQSLDPASLRKSIIPKY 181

Query: 669 DLKDMTSEELDDILRYHTEI---------VFARTSPQQKLIIVEGCQRQGAIVAVTGDGV 719
           DL  +T E L  +   H ++         VFAR +P+QK +I+   + QG +  + GDG 
Sbjct: 182 DLC-LTGESLTFLQSDHPKLLRLLLPNTRVFARVAPKQKELIITVLKAQGFVTLMCGDGT 358

Query: 720 NDSPALKKADIGVAM 734
           ND  ALK AD+GVA+
Sbjct: 359 NDVGALKHADVGVAL 403
>21541
          Length = 445

 Score = 40.4 bits (93), Expect(2) = 2e-04,   Method: Composition-based stats.
 Identities = 19/42 (45%), Positives = 28/42 (66%)
 Frame = +3

Query: 171 VIRNGEKMSINAEDVVVGDLVEVKGGDRIPADLRIISANGCK 212
           VIRNGE   I   +++VG++ ++K GD +PAD  II +N  K
Sbjct: 132 VIRNGELHQIPVGEILVGEICQIKYGDLLPADGVIIQSNDLK 257

 Score = 23.1 bits (48), Expect(2) = 2e-04,   Method: Composition-based stats.
 Identities = 9/12 (75%), Positives = 11/12 (91%)
 Frame = +1

Query: 212 KVDNSSLTGESE 223
           K+D SSLTGES+
Sbjct: 256 KIDESSLTGESD 291
>07486
          Length = 763

 Score = 37.7 bits (86), Expect = 0.021,   Method: Composition-based stats.
 Identities = 20/62 (32%), Positives = 38/62 (61%)
 Frame = -1

Query: 724 ALKKADIGVAMGIVGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSN 783
           AL +AD+G+A+G  G+DV+ +AAD++L+  +   +   ++  R      K+  A+T T +
Sbjct: 742 ALAQADVGIAIG-TGTDVAVEAADIVLMKSDLVDVYAAIKLSR------KQCGAFTSTLS 584

Query: 784 IP 785
           +P
Sbjct: 583 LP 578
>05368
          Length = 926

 Score = 32.7 bits (73), Expect = 0.85,   Method: Composition-based stats.
 Identities = 28/118 (23%), Positives = 49/118 (41%), Gaps = 13/118 (11%)
 Frame = -1

Query: 879 LPFHLLGIRETWDDRWVNDVEDSYGQQWT-YEQRKIVEFTCHTAFFVSIVVVQWADLVIC 937
           +  +++G+R+ W  RW +  +D  G+ W      +     C   FF  + ++  AD    
Sbjct: 500 IQIYVIGVRQRWRSRW-DGSDDCDGKTWICL*XGRFFGSACRLVFFJYVRLMLKADDKKL 324

Query: 938 KTRR---NSVFQQ---------GMKNKILIFGLFEETALAAFLSYCPGMGAALRMYPL 983
             RR   NSVF Q         G+K+ ++ F   +     A   +C  +  A R+  L
Sbjct: 323 AKRRSFANSVFTQP*DGP*RSAGLKHDLICFHCSDTVIKCAITLFCLXLVLAGRLQSL 150
>17101
          Length = 739

 Score = 30.8 bits (68), Expect = 2.9,   Method: Composition-based stats.
 Identities = 14/27 (51%), Positives = 17/27 (62%)
 Frame = -2

Query: 919 HTAFFVSIVVVQWADLVICKTRRNSVF 945
           HT F +S+ VV WADL +C T   S F
Sbjct: 111 HTCFRLSVCVVVWADL*LCITCEYSFF 31
>23730
          Length = 1051

 Score = 29.3 bits (64), Expect = 9.2,   Method: Composition-based stats.
 Identities = 13/54 (24%), Positives = 26/54 (48%), Gaps = 7/54 (12%)
 Frame = -2

Query: 103 LLWIGAILCFLAYGIRSATEEEPPNDDLYLG-------VVLSAVVIITGCFSYY 149
           L+W+G +  F++   R   + E P  ++Y+G       V++   +I+  C   Y
Sbjct: 315 LVWVGTLKSFMSLNTRVLAQNEQPCFNMYVGYVCVCIYVLMRVCIIMCVCMCVY 154
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|21450321|ref|NP_659170.1| Na+/K+ -ATPase alpha 3
subunit [Mus musculus]
         (1053 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

00499                                                                1092   0.0  
14773                                                                 388   e-108
06342                                                                 313   2e-85
28890                                                                 291   1e-78
08160                                                                 214   2e-55
36566                                                                 122   1e-27
12151                                                                  86   1e-25
03937                                                                 103   3e-22
33697                                                                  74   1e-21
17925                                                                  90   5e-18
29829                                                                  74   4e-13
13525                                                                  67   3e-11
04985                                                                  60   3e-09
14321                                                                  51   3e-06
21541                                                                  37   0.001
07486                                                                  36   0.065
17101                                                                  31   3.0  
>00499
          Length = 4026

 Score = 1092 bits (2823), Expect = 0.0,   Method: Compositional matrix adjust.
 Identities = 523/667 (78%), Positives = 580/667 (86%)
 Frame = +2

Query: 339  KRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTEDQSG 398
            KRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFD +I EADT++DQS 
Sbjct: 44   KRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDGRIVEADTSDDQSN 223

Query: 399  TSFDKSSHTWVALSHIAGLCNRAVFKGGQDNIPVLKRDVAGDASESALLKCIELSSGSVK 458
             ++ +S  TW+ALS +A LCNRA FKG QDN+P+LKR+  GDASESALLKC+ELS G V 
Sbjct: 224  ATYSRSDPTWMALSRVAMLCNRAEFKGNQDNVPILKRECNGDASESALLKCVELSIGHVT 403

Query: 459  LMRERNKKVAEIPFNSTNKYQLSIHETEDPNDNRYLLVMKGAPERILDRCATILLQGKEQ 518
              R RN+K+ EIPFNS+NKYQ+SIHETEDP+D RYLLVMKGAPERI+DRC+TILL GKEQ
Sbjct: 404  EYRRRNEKIVEIPFNSSNKYQVSIHETEDPDDPRYLLVMKGAPERIMDRCSTILLNGKEQ 583

Query: 519  PLDEEMKEAFQNAYXXXXXXXXXXXXFCHYYLPEEQFPKGFAFDCDDVNFTTDNLCFVGL 578
            PLD+  +EAF  AY            FC Y+LP +QFP G+ FD +  NF    L FVGL
Sbjct: 584  PLDDNFREAFNAAYLELGGLGERVLGFCDYFLPVDQFPPGYEFDPEGPNFPITGLRFVGL 763

Query: 579  MSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARL 638
            M+MIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIA+GVGIISEG++TVEDIA+  
Sbjct: 764  MAMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIARGVGIISEGSKTVEDIASER 943

Query: 639  NIPVSQVNPRDAKACVIHGTDLKDFTSEQIDEILQNHTEIVFARTSPQQKLIIVEGCQRQ 698
             IPV +V+PR+AKA VIHG DL+D T  QIDEIL+NH+EIVFARTSPQQKLIIVEGCQRQ
Sbjct: 944  GIPVEEVDPREAKAAVIHGGDLRDMTPAQIDEILRNHSEIVFARTSPQQKLIIVEGCQRQ 1123

Query: 699  GAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILLDDNFASIVTGVEEGRLI 758
            G IVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILLDDNFASIVTGVEEGRLI
Sbjct: 1124 GQIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILLDDNFASIVTGVEEGRLI 1303

Query: 759  FDNLKKSIAYTLTSNIPEITPFLLFIMANIPLPLGTITILCIDLGTDMVPAISLAYEAAE 818
            FDNLKKSIAYTLTSNIPEI+PFLLFI+A+IPLPLGTITILCIDLGTDMVPAISLAYE AE
Sbjct: 1304 FDNLKKSIAYTLTSNIPEISPFLLFILADIPLPLGTITILCIDLGTDMVPAISLAYEKAE 1483

Query: 819  SDIMKRQPRNPRTDKLVNERLISMAYGQIGMIQALGGFFSYFVILAENGFLPGNLVGIRL 878
            +DIMKRQPR+P  DKLVNERLISMAYGQIGMIQA  GFF+YFVI+ ENGF    L+GIR+
Sbjct: 1484 NDIMKRQPRDPVKDKLVNERLISMAYGQIGMIQASAGFFTYFVIMGENGFWYDRLLGIRM 1663

Query: 879  NWDDRTVNDLEDSYGQQWTYEQRKVVEFTCHTAFFVSIVVVQWADLIICKTRRNSVFQQG 938
             WD R VNDLEDSYGQ+WTY QRK +E+TCHTAFFVSIV+VQWAD+IICKTRR S+FQQG
Sbjct: 1664 EWDSRGVNDLEDSYGQEWTYSQRKKLEYTCHTAFFVSIVIVQWADIIICKTRRLSLFQQG 1843

Query: 939  MKNKILIFGLFEETALAAFLSYCPGMDVALRMYPLKPSWWFCAFPYSFLIFVYDEIRKLI 998
            MKNK LIFG+F ETALAAFL YCPG+D  LRMYPL+ +WWF A P+S  IF+YDE RKLI
Sbjct: 1844 MKNKHLIFGIFFETALAAFLCYCPGLDKGLRMYPLRLTWWFTAVPFSLTIFIYDECRKLI 2023

Query: 999  LRRNPGG 1005
            LRRNPGG
Sbjct: 2024 LRRNPGG 2044
>14773
          Length = 794

 Score =  388 bits (996), Expect = e-108,   Method: Compositional matrix adjust.
 Identities = 185/265 (69%), Positives = 217/265 (81%)
 Frame = +2

Query: 729 SDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLLFIMANI 788
           SDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEI+PFL++I+   
Sbjct: 2   SDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEISPFLVYILFGT 181

Query: 789 PLPLGTITILCIDLGTDMVPAISLAYEAAESDIMKRQPRNPRTDKLVNERLISMAYGQIG 848
           PLPLG ITIL IDLGTDMVPAISLAYE AESDIMKR PR   +D+LVNERLI+M+YGQIG
Sbjct: 182 PLPLGVITILFIDLGTDMVPAISLAYEMAESDIMKRPPRTI-SDRLVNERLIAMSYGQIG 358

Query: 849 MIQALGGFFSYFVILAENGFLPGNLVGIRLNWDDRTVNDLEDSYGQQWTYEQRKVVEFTC 908
           M+QAL GF+++ ++  ++GF+  +L GIR  WD   +NDLEDSYGQ WT  QR  VE + 
Sbjct: 359 MMQALAGFYAWILVFGQSGFMVRDLPGIRSFWDSANINDLEDSYGQNWTKAQRMDVELSG 538

Query: 909 HTAFFVSIVVVQWADLIICKTRRNSVFQQGMKNKILIFGLFEETALAAFLSYCPGMDVAL 968
           +T FF++IV+VQW+D+IICKTRR SVF QGM N +L FG+F ET+LA  LSY PG+DVAL
Sbjct: 539 YTVFFITIVLVQWSDIIICKTRRLSVFHQGMSNHVLTFGIFFETSLAVLLSYTPGVDVAL 718

Query: 969 RMYPLKPSWWFCAFPYSFLIFVYDE 993
           R  PL+  WW  A P+  LIFVYDE
Sbjct: 719 RTRPLRFEWWLAAIPFQVLIFVYDE 793
>06342
          Length = 2428

 Score =  313 bits (802), Expect = 2e-85,   Method: Compositional matrix adjust.
 Identities = 228/717 (31%), Positives = 361/717 (50%), Gaps = 61/717 (8%)
 Frame = +2

Query: 175 VVVGDLVEIKGGDRVPADLRIISAHGC--KVDNSSLTGESEPQTRSPDCTHDNPL---ET 229
           +V GD+VE+  GD+VPAD+RI+  H    ++D + LTGES    +  D   D      + 
Sbjct: 5   LVPGDIVEVSVGDKVPADIRILKIHSTTLRIDQAILTGESVSVMKHTDPIPDPRAVNQDK 184

Query: 230 RNITFFSTNCVEGTARGVVVATGDRTVMGRIATLASGLEVGKTPIAIEIEHFIQLITGVA 289
           +N+ F  TN   G  +G+V+ TG  T +G+I       E  KTP+  +++ F   ++ V 
Sbjct: 185 KNLLFSGTNVAAGKCKGLVIGTGLTTEIGKIRNEMMDTEQEKTPLQQKLDEFSNQLSKVI 364

Query: 290 VFLGVSFFILSL------ILGYTWLEAVIFLIGIIVANV----PEGXXXXXXXXXXXXXK 339
             + ++ + +++        G +W++  I+   I VA      PEG             +
Sbjct: 365 TIICIAVWAINIGHFNDPAHGGSWIKGAIYYFKIAVALAVAAIPEGLPAVITTCLALGTR 544

Query: 340 RMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTEDQSGT 399
           RMA+KN +V++L +VETLG TS ICSDKTGTLT N+M+V  ++  +QI   DT + ++ T
Sbjct: 545 RMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCKLFIFSQI---DTNQIKT-T 712

Query: 400 SFDKSSHTWVA---------------------LSHIAGLCNRAVFKGGQDNIPVLKRDVA 438
            F+ +  T+                       L  I G+CN +     +      K    
Sbjct: 713 QFEVTGSTYAPDGELYQNGKKVKASDYPGLEELCTICGMCNDSSVDYNEAKTQYEK---V 883

Query: 439 GDASESAL----------------LKCIELSSGSVKLMRERNKKVAEIPFNSTNKYQLSI 482
           G+A+E+AL                L   E+ +    ++++  +K   + F S ++  +S+
Sbjct: 884 GEATETALTVLAEKLNFYNTDKSSLNKREMGTVCNHVIQDMWRKEFTLEF-SRDRKSMSV 1060

Query: 483 -----HETEDPNDNRYLLVMKGAPERILDRCATILLQGKEQPLDEEMKEAFQNAYXXXXX 537
                  T  P   R  +  KGAPE +LDRC  + +   + P+   +K            
Sbjct: 1061FCVPNKPTRVPGGAR--MFAKGAPEGLLDRCTHVRIGNNKVPMSPAIKNEIMK--LTKIY 1228

Query: 538 XXXXXXXFCHYYLPEEQFPKGFAFDCDD----VNFTTDNLCFVGLMSMIDPPRAAVPDAV 593
                   C      +  P+    D +D    + + T N+ FVG++ M+DPPR  V  ++
Sbjct: 1229GTGRDTLRCLALATIDNPPRREDMDLEDSRKFIEYET-NMTFVGVVGMLDPPREEVMASI 1405

Query: 594 GKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPVSQVNPRDAKAC 653
             CR+AGI+VI++TGD+  TA+AI + +G+ SE +E  E +A        ++ P D +A 
Sbjct: 1406KNCRAAGIRVIVITGDNKATAEAICRRIGVFSE-SENTEGLA-YTGREFDELPPEDQRAA 1579

Query: 654 VIHGTDLKDFTSEQIDEILQNHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSP 713
           V+                       +FAR  P  K  IVE  Q +G I A+TGDGVND+P
Sbjct: 1580VMRAR--------------------LFARVEPAHKSKIVEYLQAEGEISAMTGDGVNDAP 1699

Query: 714 ALKKADIGVAMGIAGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSN 773
           ALKKA+IG+AMG +G+ V+K A++M+L DDNF++IV  VEEGR I++N+K+ I Y ++SN
Sbjct: 1700ALKKAEIGIAMG-SGTAVAKSASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSN 1876

Query: 774 IPEITPFLLFIMANIPLPLGTITILCIDLGTDMVPAISLAYEAAESDIMKRQPRNPR 830
           I E+    L     IP  L  + +L ++L TD  PA +L +   + DIM++ PRNPR
Sbjct: 1877IGEVVCIFLTAALGIPEALIPVQLLWVNLVTDGFPATALGFNPPDLDIMQKPPRNPR 2047
>28890
          Length = 552

 Score =  291 bits (744), Expect = 1e-78,   Method: Compositional matrix adjust.
 Identities = 140/183 (76%), Positives = 160/183 (87%)
 Frame = -3

Query: 132 ITGCFSYYQEAKSSKIMESFKNMVPQQALVIREGEKMQVNAEEVVVGDLVEIKGGDRVPA 191
           +TG FSYYQEAKSSKIM+SFKN+VPQ A+V+R  +K+ V AEE+VVGD+VE K GDRVPA
Sbjct: 550 VTGVFSYYQEAKSSKIMDSFKNLVPQFAVVVRGDQKLSVKAEELVVGDIVECKFGDRVPA 371

Query: 192 DLRIISAHGCKVDNSSLTGESEPQTRSPDCTHDNPLETRNITFFSTNCVEGTARGVVVAT 251
           DLR+ISAHG KVDNSSLTGESEPQ+RS + TH+NPLETRNI FFSTN VEGT RG+V+ T
Sbjct: 370 DLRVISAHGFKVDNSSLTGESEPQSRSAEFTHENPLETRNICFFSTNAVEGTCRGIVIKT 191

Query: 252 GDRTVMGRIATLASGLEVGKTPIAIEIEHFIQLITGVAVFLGVSFFILSLILGYTWLEAV 311
           GD TVMGRIA LASGLEVG TPIA EI HFI +ITGVAVFLGVSFF+++ ILGY WL+AV
Sbjct: 190 GDDTVMGRIANLASGLEVGDTPIAKEIAHFIHIITGVAVFLGVSFFVIAFILGYFWLDAV 11

Query: 312 IFL 314
           IFL
Sbjct: 10  IFL 2
>08160
          Length = 459

 Score =  214 bits (545), Expect = 2e-55,   Method: Compositional matrix adjust.
 Identities = 100/138 (72%), Positives = 116/138 (84%)
 Frame = +2

Query: 339 KRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTEDQSG 398
           KRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFD +I EADT++DQS 
Sbjct: 44  KRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDGRIVEADTSDDQSN 223

Query: 399 TSFDKSSHTWVALSHIAGLCNRAVFKGGQDNIPVLKRDVAGDASESALLKCIELSSGSVK 458
            ++ ++  TW+AL+ +  LCNRA FKG QDN+P+LKR+  GDASESALLK +ELS G V 
Sbjct: 224 ATYSRTDVTWMALARVGMLCNRAEFKGNQDNVPILKRECNGDASESALLKAVELSIGQVT 403

Query: 459 LMRERNKKVAEIPFNSTN 476
             R RNKK+ EIPFNS+N
Sbjct: 404 EYRRRNKKIVEIPFNSSN 457
>36566
          Length = 589

 Score =  122 bits (305), Expect = 1e-27,   Method: Compositional matrix adjust.
 Identities = 60/146 (41%), Positives = 100/146 (68%)
 Frame = +3

Query: 695 CQRQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILLDDNFASIVTGVEE 754
            Q+ G +V +TGDGVND+ ALK A+IG++MG++G+DVSK+A+DMIL+DD+F +I+  +EE
Sbjct: 108 LQQNGLVVGMTGDGVNDAVALKSAEIGISMGVSGTDVSKEASDMILVDDDFTTILNAIEE 287

Query: 755 GRLIFDNLKKSIAYTLTSNIPEITPFLLFIMANIPLPLGTITILCIDLGTDMVPAISLAY 814
           G+ IF N++  + + L+++I  ++   +  +  +P PL  + IL I++  D  PA SL  
Sbjct: 288 GKGIFYNIRNFVRFQLSTSIAALSLIAVSTLLRLPNPLNAMQILWINIIMDGPPAQSLGV 467

Query: 815 EAAESDIMKRQPRNPRTDKLVNERLI 840
           E  + D++K+ PR+   D ++  RLI
Sbjct: 468 EPVDHDVIKQPPRH-VGDPIITRRLI 542
>12151
          Length = 880

 Score = 85.5 bits (210), Expect(2) = 1e-25,   Method: Compositional matrix adjust.
 Identities = 51/141 (36%), Positives = 86/141 (60%), Gaps = 3/141 (2%)
 Frame = +3

Query: 716 KKADIGVAMGIAGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIP 775
           +KAD+G AMGI+G+DV+K+A+D+IL DDNF SIV  V  GR ++D++ K + + LT N+ 
Sbjct: 288 QKADVGFAMGISGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSIAKFLQFQLTVNVV 467

Query: 776 EITPFLLFIMANIPLPLGTITILCIDLGTDMVPAISLAYEAAESDIMKRQP---RNPRTD 832
            +    +   +    PL  I +L ++L  D + +++LA E   S+++KR+P     P   
Sbjct: 468 AVFVAFVGACSIGDSPLKAIQMLWVNLIMDTLASLALATELPSSELLKRRPYGRTKPLIS 647

Query: 833 KLVNERLISMAYGQIGMIQAL 853
           K + + ++  A+ QI +I  L
Sbjct: 648 KTMWKNILGHAFYQILVILLL 710

 Score = 50.4 bits (119), Expect(2) = 1e-25,   Method: Compositional matrix adjust.
 Identities = 40/114 (35%), Positives = 57/114 (50%), Gaps = 5/114 (4%)
 Frame = +1

Query: 609 DHPITAKAIAKGVGIISEGNETVEDIAARLNIPVSQVNPRDAKACVIHGTDLKDFTSEQI 668
           D+  TA++IA   GII  G++ +       N  +     RDA+          + + E++
Sbjct: 1   DNVNTARSIASKCGIIQPGDDGLVLEGKEFNQLI-----RDAEG---------EISQEKV 138

Query: 669 DEILQNHTEIVFARTSPQQKLIIVE-----GCQRQGAIVAVTGDGVNDSPALKK 717
           DE+  N    V AR+SPQ K I+V+            +VAVTGDG ND PALKK
Sbjct: 139 DEVWPNLR--VLARSSPQDKYILVKHIIDSKVSTSREVVAVTGDGTNDGPALKK 294
>03937
          Length = 1558

 Score =  103 bits (258), Expect = 3e-22,   Method: Composition-based stats.
 Identities = 45/70 (64%), Positives = 50/70 (71%)
 Frame = -2

Query: 936  QQGMKNKILIFGLFEETALAAFLSYCPGMDVALRMYPLKPSWWFCAFPYSFLIFVYDEIR 995
            QQGMKNK LIF  F       FL YCPG+D  LRMYPL+ +WWF A P+S  IF+YDE R
Sbjct: 1557 QQGMKNKHLIFDXFF*DGAGRFLCYCPGLDKGLRMYPLRLTWWFTAVPFSLTIFIYDECR 1378

Query: 996  KLILRRNPGG 1005
            KLILRR PGG
Sbjct: 1377 KLILRRXPGG 1348
>33697
          Length = 310

 Score = 73.9 bits (180), Expect(2) = 1e-21,   Method: Compositional matrix adjust.
 Identities = 34/37 (91%), Positives = 36/37 (97%)
 Frame = -2

Query: 580 SMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKA 616
           SMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPIT++ 
Sbjct: 204 SMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITSQG 94

 Score = 48.5 bits (114), Expect(2) = 1e-21,   Method: Compositional matrix adjust.
 Identities = 24/33 (72%), Positives = 28/33 (84%)
 Frame = -3

Query: 614 AKAIAKGVGIISEGNETVEDIAARLNIPVSQVN 646
           AKAIAKGVGIISEG+ TVEDI+A   IPV +V+
Sbjct: 101 AKAIAKGVGIISEGSRTVEDISAERGIPVEEVD 3
>17925
          Length = 510

 Score = 90.1 bits (222), Expect = 5e-18,   Method: Compositional matrix adjust.
 Identities = 43/60 (71%), Positives = 50/60 (83%)
 Frame = +3

Query: 648 RDAKACVIHGTDLKDFTSEQIDEILQNHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGD 707
           R+A+A VIHG DLK+  ++ ID+IL N  EIVFARTSPQQKLIIVEGCQR G IVAVTG+
Sbjct: 315 REAEAIVIHGGDLKNMDAKDIDDILHNFVEIVFARTSPQQKLIIVEGCQRNGQIVAVTGE 494
>29829
          Length = 465

 Score = 73.6 bits (179), Expect = 4e-13,   Method: Compositional matrix adjust.
 Identities = 44/127 (34%), Positives = 77/127 (60%)
 Frame = -3

Query: 720 IGVAMGIAGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITP 779
           +G AMGI+G+DV+K+A+D+IL DDNF SIV  V  GR ++D++ K + + LT N+  +  
Sbjct: 460 LGFAMGISGTDVAKEASDIILTDDNFTSIVKAVXWGRNVYDSIAKFLQFQLTVNVVAVFV 281

Query: 780 FLLFIMANIPLPLGTITILCIDLGTDMVPAISLAYEAAESDIMKRQPRNPRTDKLVNERL 839
             +   +    PL  I +L ++L  D + +++LA E   ++++KR+P   RT  L+++ +
Sbjct: 280 AFVGACSIGDSPLEAIQMLWVNLIMDTLASLALATELPSNELLKRKPYG-RTKPLISKTM 104

Query: 840 ISMAYGQ 846
                G 
Sbjct: 103 FKNIAGH 83
>13525
          Length = 645

 Score = 67.4 bits (163), Expect = 3e-11,   Method: Composition-based stats.
 Identities = 35/57 (61%), Positives = 39/57 (68%)
 Frame = +2

Query: 339 KRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTED 395
           KRMARKNCLVKNLEAVETLGSTSTICSDKTG   +           +  HE+ T +D
Sbjct: 11  KRMARKNCLVKNLEAVETLGSTSTICSDKTGCGEERGARGGGG---DDGHESKTHQD 172
>04985
          Length = 1671

 Score = 60.5 bits (145), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 46/149 (30%), Positives = 67/149 (44%), Gaps = 1/149 (0%)
 Frame = -1

Query: 679  VFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADM 738
            VFAR +P QK  ++E  Q    IV + GDG ND  ALK A  G+++  A + V+      
Sbjct: 1608 VFARMAPDQKCALIENLQSYDYIVGMCGDGANDCEALKAAHAGISLSEAEASVAAPFTSR 1429

Query: 739  ILLDDNFASIVTGVEEGRLIFDNLKKSIAY-TLTSNIPEITPFLLFIMANIPLPLGTITI 797
            I   +N   +VT + EGR           Y  L S I  I+  +L+        L  +  
Sbjct: 1428 I---NNIECVVTAMREGRAALVTSFGCFKYMALYSFIQFISVLILYTCQT---NLSDLEF 1267

Query: 798  LCIDLGTDMVPAISLAYEAAESDIMKRQP 826
            L IDL      A+ L Y  A   +++ +P
Sbjct: 1266 LYIDLIITTTIAVLLGYTGAYDKLVRHKP 1180
>14321
          Length = 568

 Score = 50.8 bits (120), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 40/135 (29%), Positives = 67/135 (49%), Gaps = 19/135 (14%)
 Frame = +2

Query: 609 DHPITAKAIAKGVGIISEGNETVEDIAARLNI---------PVSQ-VNPRDAKACVIHGT 658
           D+P+TA  +AK + +  +    +     RL+           V+Q ++P   +  +I   
Sbjct: 2   DNPLTACHVAKELRMTRKDKTLILTPPNRLDSDWHWQSIDDSVTQSLDPASLRKSIIPKY 181

Query: 659 DLKDFTSEQIDEILQNHTEI---------VFARTSPQQKLIIVEGCQRQGAIVAVTGDGV 709
           DL   T E +  +  +H ++         VFAR +P+QK +I+   + QG +  + GDG 
Sbjct: 182 DLC-LTGESLTFLQSDHPKLLRLLLPNTRVFARVAPKQKELIITVLKAQGFVTLMCGDGT 358

Query: 710 NDSPALKKADIGVAM 724
           ND  ALK AD+GVA+
Sbjct: 359 NDVGALKHADVGVAL 403
>21541
          Length = 445

 Score = 36.6 bits (83), Expect(2) = 0.001,   Method: Compositional matrix adjust.
 Identities = 23/67 (34%), Positives = 39/67 (58%)
 Frame = +3

Query: 136 FSYYQEAKSSKIMESFKNMVPQQALVIREGEKMQVNAEEVVVGDLVEIKGGDRVPADLRI 195
           F+ + + K  + ++S K     +  VIR GE  Q+   E++VG++ +IK GD +PAD  I
Sbjct: 60  FNDWSKEKQFRGLQS-KIEHEHRFTVIRNGELHQIPVGEILVGEICQIKYGDLLPADGVI 236

Query: 196 ISAHGCK 202
           I ++  K
Sbjct: 237 IQSNDLK 257

 Score = 24.3 bits (51), Expect(2) = 0.001,   Method: Composition-based stats.
 Identities = 16/45 (35%), Positives = 23/45 (51%), Gaps = 1/45 (2%)
 Frame = +1

Query: 202 KVDNSSLTGESEPQTRSPDCTHDNPLETRNITFFS-TNCVEGTAR 245
           K+D SSLTGES+         H    E ++    S T+ +EG+ R
Sbjct: 256 KIDESSLTGESD---------HVKKGEAKDPMLLSGTHVMEGSGR 363
>07486
          Length = 763

 Score = 36.2 bits (82), Expect = 0.065,   Method: Compositional matrix adjust.
 Identities = 20/62 (32%), Positives = 38/62 (61%)
 Frame = -1

Query: 714 ALKKADIGVAMGIAGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSN 773
           AL +AD+G+A+G  G+DV+ +AAD++L+  +   +   ++  R      K+  A+T T +
Sbjct: 742 ALAQADVGIAIG-TGTDVAVEAADIVLMKSDLVDVYAAIKLSR------KQCGAFTSTLS 584

Query: 774 IP 775
           +P
Sbjct: 583 LP 578
>17101
          Length = 739

 Score = 30.8 bits (68), Expect = 3.0,   Method: Composition-based stats.
 Identities = 14/27 (51%), Positives = 17/27 (62%)
 Frame = -2

Query: 909 HTAFFVSIVVVQWADLIICKTRRNSVF 935
           HT F +S+ VV WADL +C T   S F
Sbjct: 111 HTCFRLSVCVVVWADL*LCITCEYSFF 31
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|30409956|ref|NP_848492.1| Na+/K+ -ATPase alpha 2
subunit [Mus musculus]
         (1020 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

00499                                                                1101   0.0  
14773                                                                 379   e-105
06342                                                                 320   1e-87
28890                                                                 305   8e-83
08160                                                                 205   6e-53
36566                                                                 123   3e-28
03937                                                                 118   1e-26
12151                                                                  83   2e-24
33697                                                                  76   1e-22
17925                                                                  91   3e-18
29829                                                                  72   8e-13
13525                                                                  68   2e-11
04985                                                                  61   2e-09
14321                                                                  53   7e-07
21541                                                                  40   1e-04
07486                                                                  38   0.021
18443                                                                  33   0.69 
17101                                                                  30   5.7  
>00499
          Length = 4026

 Score = 1101 bits (2847), Expect = 0.0,   Method: Compositional matrix adjust.
 Identities = 528/675 (78%), Positives = 589/675 (87%), Gaps = 1/675 (0%)
 Frame = +2

Query: 347  KRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTEDQSG 406
            KRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFD +I EADT++DQS 
Sbjct: 44   KRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDGRIVEADTSDDQSN 223

Query: 407  ATFDKRSPTWTALSRIAGLCNRAVFKAGQENISVSKRDTAGDASESALLKCIELSCGSVR 466
            AT+ +  PTW ALSR+A LCNRA FK  Q+N+ + KR+  GDASESALLKC+ELS G V 
Sbjct: 224  ATYSRSDPTWMALSRVAMLCNRAEFKGNQDNVPILKRECNGDASESALLKCVELSIGHVT 403

Query: 467  KMRDRNPKVAEIPFNSTNKYQLSIHEREDSPQ-SHVLVMKGAPERILDRCSTILVQGKEI 525
            + R RN K+ EIPFNS+NKYQ+SIHE ED     ++LVMKGAPERI+DRCSTIL+ GKE 
Sbjct: 404  EYRRRNEKIVEIPFNSSNKYQVSIHETEDPDDPRYLLVMKGAPERIMDRCSTILLNGKEQ 583

Query: 526  PLDKEMQDAFQNAYMELGGLGERVLGFCQLNLPSGKFPRGFKFDTDELNFPTEKLCFVGL 585
            PLD   ++AF  AY+ELGGLGERVLGFC   LP  +FP G++FD +  NFP   L FVGL
Sbjct: 584  PLDDNFREAFNAAYLELGGLGERVLGFCDYFLPVDQFPPGYEFDPEGPNFPITGLRFVGL 763

Query: 586  MSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARL 645
            M+MIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIA+GVGIISEG++TVEDIA+  
Sbjct: 764  MAMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIARGVGIISEGSKTVEDIASER 943

Query: 646  NIPVSQVNPREAKACVVHGSDLKDMTSEQLDEILRDHTEIVFARTSPQQKLIIVEGCQRQ 705
             IPV +V+PREAKA V+HG DL+DMT  Q+DEILR+H+EIVFARTSPQQKLIIVEGCQRQ
Sbjct: 944  GIPVEEVDPREAKAAVIHGGDLRDMTPAQIDEILRNHSEIVFARTSPQQKLIIVEGCQRQ 1123

Query: 706  GAIVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQAADMILLDDNFASIVTGVEEGRLI 765
            G IVAVTGDGVNDSPALKKADIG+AMGI+GSDVSKQAADMILLDDNFASIVTGVEEGRLI
Sbjct: 1124 GQIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILLDDNFASIVTGVEEGRLI 1303

Query: 766  FDNLKKSIAYTLTSNIPEITPFLLFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEAAE 825
            FDNLKKSIAYTLTSNIPEI+PFLLFI+A+IPLPLGT+TILCIDLGTDMVPAISLAYE AE
Sbjct: 1304 FDNLKKSIAYTLTSNIPEISPFLLFILADIPLPLGTITILCIDLGTDMVPAISLAYEKAE 1483

Query: 826  SDIMKRQPRNSQTDKLVNERLISMAYGQIGMIQALGGFFTYFVILAENGFLPSRLLGIRL 885
            +DIMKRQPR+   DKLVNERLISMAYGQIGMIQA  GFFTYFVI+ ENGF   RLLGIR+
Sbjct: 1484 NDIMKRQPRDPVKDKLVNERLISMAYGQIGMIQASAGFFTYFVIMGENGFWYDRLLGIRM 1663

Query: 886  DWDDRTTNDLEDSYGQEWTYEQRKVVEFTCHTAFFASIVVVQWADLIICKTRRNSVFQQG 945
            +WD R  NDLEDSYGQEWTY QRK +E+TCHTAFF SIV+VQWAD+IICKTRR S+FQQG
Sbjct: 1664 EWDSRGVNDLEDSYGQEWTYSQRKKLEYTCHTAFFVSIVIVQWADIIICKTRRLSLFQQG 1843

Query: 946  MKNKILIFGLLEETALAAFLSYCPGMGVALRMYPLKVTWWFCAFPYSLLIFIYDEVRKLI 1005
            MKNK LIFG+  ETALAAFL YCPG+   LRMYPL++TWWF A P+SL IFIYDE RKLI
Sbjct: 1844 MKNKHLIFGIFFETALAAFLCYCPGLDKGLRMYPLRLTWWFTAVPFSLTIFIYDECRKLI 2023

Query: 1006 LRRYPGGWVEKETYY 1020
            LRR PGG+VE+ETYY
Sbjct: 2024 LRRNPGGFVERETYY 2068
>14773
          Length = 794

 Score =  379 bits (972), Expect = e-105,   Method: Compositional matrix adjust.
 Identities = 181/265 (68%), Positives = 213/265 (80%)
 Frame = +2

Query: 736  SDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLLFIIANI 795
            SDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEI+PFL++I+   
Sbjct: 2    SDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEISPFLVYILFGT 181

Query: 796  PLPLGTVTILCIDLGTDMVPAISLAYEAAESDIMKRQPRNSQTDKLVNERLISMAYGQIG 855
            PLPLG +TIL IDLGTDMVPAISLAYE AESDIMKR PR + +D+LVNERLI+M+YGQIG
Sbjct: 182  PLPLGVITILFIDLGTDMVPAISLAYEMAESDIMKRPPR-TISDRLVNERLIAMSYGQIG 358

Query: 856  MIQALGGFFTYFVILAENGFLPSRLLGIRLDWDDRTTNDLEDSYGQEWTYEQRKVVEFTC 915
            M+QAL GF+ + ++  ++GF+   L GIR  WD    NDLEDSYGQ WT  QR  VE + 
Sbjct: 359  MMQALAGFYAWILVFGQSGFMVRDLPGIRSFWDSANINDLEDSYGQNWTKAQRMDVELSG 538

Query: 916  HTAFFASIVVVQWADLIICKTRRNSVFQQGMKNKILIFGLLEETALAAFLSYCPGMGVAL 975
            +T FF +IV+VQW+D+IICKTRR SVF QGM N +L FG+  ET+LA  LSY PG+ VAL
Sbjct: 539  YTVFFITIVLVQWSDIIICKTRRLSVFHQGMSNHVLTFGIFFETSLAVLLSYTPGVDVAL 718

Query: 976  RMYPLKVTWWFCAFPYSLLIFIYDE 1000
            R  PL+  WW  A P+ +LIF+YDE
Sbjct: 719  RTRPLRFEWWLAAIPFQVLIFVYDE 793
>06342
          Length = 2428

 Score =  320 bits (821), Expect = 1e-87,   Method: Compositional matrix adjust.
 Identities = 236/722 (32%), Positives = 373/722 (51%), Gaps = 67/722 (9%)
 Frame = +2

Query: 183 VVVGDLVEVKGGDRVPADLRIISSHGC--KVDNSSLTGESEPQTRSPEFTHENPL----- 235
           +V GD+VEV  GD+VPAD+RI+  H    ++D + LTGES    +     H +P+     
Sbjct: 5   LVPGDIVEVSVGDKVPADIRILKIHSTTLRIDQAILTGESVSVMK-----HTDPIPDPRA 169

Query: 236 ---ETRNICFFSTNCVEGTARGIVIATGDRTVMGRIATLASGLEVGQTPIAMEIEHFIQL 292
              + +N+ F  TN   G  +G+VI TG  T +G+I       E  +TP+  +++ F   
Sbjct: 170 VNQDKKNLLFSGTNVAAGKCKGLVIGTGLTTEIGKIRNEMMDTEQEKTPLQQKLDEFSNQ 349

Query: 293 ITGVAVFLGVSFFVLSL------ILGYSWLEAVIFLIGIIVANV----PEGXXXXXXXXX 342
           ++ V   + ++ + +++        G SW++  I+   I VA      PEG         
Sbjct: 350 LSKVITIICIAVWAINIGHFNDPAHGGSWIKGAIYYFKIAVALAVAAIPEGLPAVITTCL 529

Query: 343 XXXXKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQI--HEADT 400
               +RMA+KN +V++L +VETLG TS ICSDKTGTLT N+M+V  ++  +QI  ++  T
Sbjct: 530 ALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCKLFIFSQIDTNQIKT 709

Query: 401 TE-DQSGATFDKRS--------------PTWTALSRIAGLCNRAVFKAGQENISVSKRDT 445
           T+ + +G+T+                  P    L  I G+CN +       N + ++ + 
Sbjct: 710 TQFEVTGSTYAPDGELYQNGKKVKASDYPGLEELCTICGMCNDSSV---DYNEAKTQYEK 880

Query: 446 AGDASESAL----------------LKCIELSCGSVRKMRDRNPKVAEIPFNSTNKYQLS 489
            G+A+E+AL                L   E+       ++D   K   + F S ++  +S
Sbjct: 881 VGEATETALTVLAEKLNFYNTDKSSLNKREMGTVCNHVIQDMWRKEFTLEF-SRDRKSMS 1057

Query: 490 I----HEREDSPQSHVLVMKGAPERILDRCSTILVQGKEIPLDKEMQDAFQNAYMELG-- 543
           +    ++    P    +  KGAPE +LDRC+ + +   ++P    M  A +N  M+L   
Sbjct: 1058VFCVPNKPTRVPGGARMFAKGAPEGLLDRCTHVRIGNNKVP----MSPAIKNEIMKLTKI 1225

Query: 544 -GLGE---RVLGFCQLNLPSGKFPRGFKFDTDE----LNFPTEKLCFVGLMSMIDPPRAA 595
            G G    R L    ++ P    PR    D ++    + + T  + FVG++ M+DPPR  
Sbjct: 1226YGTGRDTLRCLALATIDNP----PRREDMDLEDSRKFIEYET-NMTFVGVVGMLDPPREE 1390

Query: 596 VPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPVSQVNPR 655
           V  ++  CR+AGI+VI++TGD+  TA+AI + +G+ SE +E  E +A        ++ P 
Sbjct: 1391VMASIKNCRAAGIRVIVITGDNKATAEAICRRIGVFSE-SENTEGLA-YTGREFDELPPE 1564

Query: 656 EAKACVVHGSDLKDMTSEQLDEILRDHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDG 715
           + +A V+                       +FAR  P  K  IVE  Q +G I A+TGDG
Sbjct: 1565DQRAAVMRAR--------------------LFARVEPAHKSKIVEYLQAEGEISAMTGDG 1684

Query: 716 VNDSPALKKADIGIAMGISGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAY 775
           VND+PALKKA+IGIAMG SG+ V+K A++M+L DDNF++IV  VEEGR I++N+K+ I Y
Sbjct: 1685VNDAPALKKAEIGIAMG-SGTAVAKSASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRY 1861

Query: 776 TLTSNIPEITPFLLFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEAAESDIMKRQPRN 835
            ++SNI E+    L     IP  L  V +L ++L TD  PA +L +   + DIM++ PRN
Sbjct: 1862LISSNIGEVVCIFLTAALGIPEALIPVQLLWVNLVTDGFPATALGFNPPDLDIMQKPPRN 2041

Query: 836 SQ 837
            +
Sbjct: 2042PR 2047
>28890
          Length = 552

 Score =  305 bits (780), Expect = 8e-83,   Method: Compositional matrix adjust.
 Identities = 147/183 (80%), Positives = 162/183 (88%)
 Frame = -3

Query: 140 VTGCFSYYQEAKSSKIMDSFKNMVPQQALVIREGEKMQINAEEVVVGDLVEVKGGDRVPA 199
           VTG FSYYQEAKSSKIMDSFKN+VPQ A+V+R  +K+ + AEE+VVGD+VE K GDRVPA
Sbjct: 550 VTGVFSYYQEAKSSKIMDSFKNLVPQFAVVVRGDQKLSVKAEELVVGDIVECKFGDRVPA 371

Query: 200 DLRIISSHGCKVDNSSLTGESEPQTRSPEFTHENPLETRNICFFSTNCVEGTARGIVIAT 259
           DLR+IS+HG KVDNSSLTGESEPQ+RS EFTHENPLETRNICFFSTN VEGT RGIVI T
Sbjct: 370 DLRVISAHGFKVDNSSLTGESEPQSRSAEFTHENPLETRNICFFSTNAVEGTCRGIVIKT 191

Query: 260 GDRTVMGRIATLASGLEVGQTPIAMEIEHFIQLITGVAVFLGVSFFVLSLILGYSWLEAV 319
           GD TVMGRIA LASGLEVG TPIA EI HFI +ITGVAVFLGVSFFV++ ILGY WL+AV
Sbjct: 190 GDDTVMGRIANLASGLEVGDTPIAKEIAHFIHIITGVAVFLGVSFFVIAFILGYFWLDAV 11

Query: 320 IFL 322
           IFL
Sbjct: 10  IFL 2
>08160
          Length = 459

 Score =  205 bits (522), Expect = 6e-53,   Method: Compositional matrix adjust.
 Identities = 98/138 (71%), Positives = 113/138 (81%)
 Frame = +2

Query: 347 KRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTEDQSG 406
           KRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFD +I EADT++DQS 
Sbjct: 44  KRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDGRIVEADTSDDQSN 223

Query: 407 ATFDKRSPTWTALSRIAGLCNRAVFKAGQENISVSKRDTAGDASESALLKCIELSCGSVR 466
           AT+ +   TW AL+R+  LCNRA FK  Q+N+ + KR+  GDASESALLK +ELS G V 
Sbjct: 224 ATYSRTDVTWMALARVGMLCNRAEFKGNQDNVPILKRECNGDASESALLKAVELSIGQVT 403

Query: 467 KMRDRNPKVAEIPFNSTN 484
           + R RN K+ EIPFNS+N
Sbjct: 404 EYRRRNKKIVEIPFNSSN 457
>36566
          Length = 589

 Score =  123 bits (309), Expect = 3e-28,   Method: Compositional matrix adjust.
 Identities = 62/146 (42%), Positives = 100/146 (68%)
 Frame = +3

Query: 702 CQRQGAIVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQAADMILLDDNFASIVTGVEE 761
            Q+ G +V +TGDGVND+ ALK A+IGI+MG+SG+DVSK+A+DMIL+DD+F +I+  +EE
Sbjct: 108 LQQNGLVVGMTGDGVNDAVALKSAEIGISMGVSGTDVSKEASDMILVDDDFTTILNAIEE 287

Query: 762 GRLIFDNLKKSIAYTLTSNIPEITPFLLFIIANIPLPLGTVTILCIDLGTDMVPAISLAY 821
           G+ IF N++  + + L+++I  ++   +  +  +P PL  + IL I++  D  PA SL  
Sbjct: 288 GKGIFYNIRNFVRFQLSTSIAALSLIAVSTLLRLPNPLNAMQILWINIIMDGPPAQSLGV 467

Query: 822 EAAESDIMKRQPRNSQTDKLVNERLI 847
           E  + D++K+ PR+   D ++  RLI
Sbjct: 468 EPVDHDVIKQPPRHVG-DPIITRRLI 542
>03937
          Length = 1558

 Score =  118 bits (296), Expect = 1e-26,   Method: Composition-based stats.
 Identities = 52/78 (66%), Positives = 58/78 (74%)
 Frame = -2

Query: 943  QQGMKNKILIFGLLEETALAAFLSYCPGMGVALRMYPLKVTWWFCAFPYSLLIFIYDEVR 1002
            QQGMKNK LIF          FL YCPG+   LRMYPL++TWWF A P+SL IFIYDE R
Sbjct: 1557 QQGMKNKHLIFDXFF*DGAGRFLCYCPGLDKGLRMYPLRLTWWFTAVPFSLTIFIYDECR 1378

Query: 1003 KLILRRYPGGWVEKETYY 1020
            KLILRR PGG+VE+ETYY
Sbjct: 1377 KLILRRXPGGFVERETYY 1324
>12151
          Length = 880

 Score = 83.2 bits (204), Expect(2) = 2e-24,   Method: Compositional matrix adjust.
 Identities = 51/148 (34%), Positives = 86/148 (58%)
 Frame = +3

Query: 723 KKADIGIAMGISGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIP 782
           +KAD+G AMGISG+DV+K+A+D+IL DDNF SIV  V  GR ++D++ K + + LT N+ 
Sbjct: 288 QKADVGFAMGISGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSIAKFLQFQLTVNVV 467

Query: 783 EITPFLLFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEAAESDIMKRQPRNSQTDKLV 842
            +    +   +    PL  + +L ++L  D + +++LA E   S+++KR+P   +T  L+
Sbjct: 468 AVFVAFVGACSIGDSPLKAIQMLWVNLIMDTLASLALATELPSSELLKRRPY-GRTKPLI 644

Query: 843 NERLISMAYGQIGMIQALGGFFTYFVIL 870
           ++ +     G          F+   VIL
Sbjct: 645 SKTMWKNILGH--------AFYQILVIL 704

 Score = 48.9 bits (115), Expect(2) = 2e-24,   Method: Composition-based stats.
 Identities = 38/114 (33%), Positives = 58/114 (50%), Gaps = 5/114 (4%)
 Frame = +1

Query: 616 DHPITAKAIAKGVGIISEGNETVEDIAARLNIPVSQVNPREAKACVVHGSDLKDMTSEQL 675
           D+  TA++IA   GII  G++ +       N  +     R+A+          +++ E++
Sbjct: 1   DNVNTARSIASKCGIIQPGDDGLVLEGKEFNQLI-----RDAEG---------EISQEKV 138

Query: 676 DEILRDHTEIVFARTSPQQKLIIVE-----GCQRQGAIVAVTGDGVNDSPALKK 724
           DE+  +    V AR+SPQ K I+V+            +VAVTGDG ND PALKK
Sbjct: 139 DEVWPNLR--VLARSSPQDKYILVKHIIDSKVSTSREVVAVTGDGTNDGPALKK 294
>33697
          Length = 310

 Score = 76.3 bits (186), Expect(3) = 1e-22,   Method: Composition-based stats.
 Identities = 34/37 (91%), Positives = 36/37 (97%)
 Frame = -2

Query: 587 SMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKA 623
           SMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPIT++ 
Sbjct: 204 SMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITSQG 94

 Score = 48.1 bits (113), Expect(3) = 1e-22,   Method: Compositional matrix adjust.
 Identities = 24/33 (72%), Positives = 28/33 (84%)
 Frame = -3

Query: 621 AKAIAKGVGIISEGNETVEDIAARLNIPVSQVN 653
           AKAIAKGVGIISEG+ TVEDI+A   IPV +V+
Sbjct: 101 AKAIAKGVGIISEGSRTVEDISAERGIPVEEVD 3

 Score = 21.2 bits (43), Expect(3) = 1e-22,   Method: Composition-based stats.
 Identities = 9/13 (69%), Positives = 9/13 (69%)
 Frame = -1

Query: 574 NFPTEKLCFVGLM 586
           NFP   L FVGLM
Sbjct: 244 NFPITGLRFVGLM 206
>17925
          Length = 510

 Score = 90.5 bits (223), Expect = 3e-18,   Method: Compositional matrix adjust.
 Identities = 42/60 (70%), Positives = 51/60 (85%)
 Frame = +3

Query: 655 REAKACVVHGSDLKDMTSEQLDEILRDHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGD 714
           REA+A V+HG DLK+M ++ +D+IL +  EIVFARTSPQQKLIIVEGCQR G IVAVTG+
Sbjct: 315 REAEAIVIHGGDLKNMDAKDIDDILHNFVEIVFARTSPQQKLIIVEGCQRNGQIVAVTGE 494
>29829
          Length = 465

 Score = 72.4 bits (176), Expect = 8e-13,   Method: Compositional matrix adjust.
 Identities = 43/127 (33%), Positives = 77/127 (60%)
 Frame = -3

Query: 727 IGIAMGISGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITP 786
           +G AMGISG+DV+K+A+D+IL DDNF SIV  V  GR ++D++ K + + LT N+  +  
Sbjct: 460 LGFAMGISGTDVAKEASDIILTDDNFTSIVKAVXWGRNVYDSIAKFLQFQLTVNVVAVFV 281

Query: 787 FLLFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEAAESDIMKRQPRNSQTDKLVNERL 846
             +   +    PL  + +L ++L  D + +++LA E   ++++KR+P   +T  L+++ +
Sbjct: 280 AFVGACSIGDSPLEAIQMLWVNLIMDTLASLALATELPSNELLKRKPYG-RTKPLISKTM 104

Query: 847 ISMAYGQ 853
                G 
Sbjct: 103 FKNIAGH 83
>13525
          Length = 645

 Score = 67.8 bits (164), Expect = 2e-11,   Method: Composition-based stats.
 Identities = 35/57 (61%), Positives = 39/57 (68%)
 Frame = +2

Query: 347 KRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTED 403
           KRMARKNCLVKNLEAVETLGSTSTICSDKTG   +           +  HE+ T +D
Sbjct: 11  KRMARKNCLVKNLEAVETLGSTSTICSDKTGCGEERGARGGGG---DDGHESKTHQD 172
>04985
          Length = 1671

 Score = 61.2 bits (147), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 47/152 (30%), Positives = 69/152 (45%), Gaps = 1/152 (0%)
 Frame = -1

Query: 686  VFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQAADM 745
            VFAR +P QK  ++E  Q    IV + GDG ND  ALK A  GI++  + + V+      
Sbjct: 1608 VFARMAPDQKCALIENLQSYDYIVGMCGDGANDCEALKAAHAGISLSEAEASVAAPFTSR 1429

Query: 746  ILLDDNFASIVTGVEEGRLIFDNLKKSIAY-TLTSNIPEITPFLLFIIANIPLPLGTVTI 804
            I   +N   +VT + EGR           Y  L S I  I+  +L+        L  +  
Sbjct: 1428 I---NNIECVVTAMREGRAALVTSFGCFKYMALYSFIQFISVLILYTCQT---NLSDLEF 1267

Query: 805  LCIDLGTDMVPAISLAYEAAESDIMKRQPRNS 836
            L IDL      A+ L Y  A   +++ +P +S
Sbjct: 1266 LYIDLIITTTIAVLLGYTGAYDKLVRHKPPDS 1171
>14321
          Length = 568

 Score = 52.8 bits (125), Expect = 7e-07,   Method: Compositional matrix adjust.
 Identities = 40/135 (29%), Positives = 68/135 (50%), Gaps = 19/135 (14%)
 Frame = +2

Query: 616 DHPITAKAIAKGVGIISEGNETVEDIAARLNI---------PVSQ-VNPREAKACVVHGS 665
           D+P+TA  +AK + +  +    +     RL+           V+Q ++P   +  ++   
Sbjct: 2   DNPLTACHVAKELRMTRKDKTLILTPPNRLDSDWHWQSIDDSVTQSLDPASLRKSIIPKY 181

Query: 666 DLKDMTSEQLDEILRDHTEI---------VFARTSPQQKLIIVEGCQRQGAIVAVTGDGV 716
           DL  +T E L  +  DH ++         VFAR +P+QK +I+   + QG +  + GDG 
Sbjct: 182 DLC-LTGESLTFLQSDHPKLLRLLLPNTRVFARVAPKQKELIITVLKAQGFVTLMCGDGT 358

Query: 717 NDSPALKKADIGIAM 731
           ND  ALK AD+G+A+
Sbjct: 359 NDVGALKHADVGVAL 403
>21541
          Length = 445

 Score = 40.4 bits (93), Expect(2) = 1e-04,   Method: Composition-based stats.
 Identities = 20/42 (47%), Positives = 28/42 (66%)
 Frame = +3

Query: 169 VIREGEKMQINAEEVVVGDLVEVKGGDRVPADLRIISSHGCK 210
           VIR GE  QI   E++VG++ ++K GD +PAD  II S+  K
Sbjct: 132 VIRNGELHQIPVGEILVGEICQIKYGDLLPADGVIIQSNDLK 257

 Score = 24.3 bits (51), Expect(2) = 1e-04,   Method: Composition-based stats.
 Identities = 16/45 (35%), Positives = 23/45 (51%), Gaps = 1/45 (2%)
 Frame = +1

Query: 210 KVDNSSLTGESEPQTRSPEFTHENPLETRNICFFS-TNCVEGTAR 253
           K+D SSLTGES+         H    E ++    S T+ +EG+ R
Sbjct: 256 KIDESSLTGESD---------HVKKGEAKDPMLLSGTHVMEGSGR 363
>07486
          Length = 763

 Score = 37.7 bits (86), Expect = 0.021,   Method: Compositional matrix adjust.
 Identities = 21/62 (33%), Positives = 39/62 (62%)
 Frame = -1

Query: 721 ALKKADIGIAMGISGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSN 780
           AL +AD+GIA+G +G+DV+ +AAD++L+  +   +   ++  R      K+  A+T T +
Sbjct: 742 ALAQADVGIAIG-TGTDVAVEAADIVLMKSDLVDVYAAIKLSR------KQCGAFTSTLS 584

Query: 781 IP 782
           +P
Sbjct: 583 LP 578
>18443
          Length = 945

 Score = 32.7 bits (73), Expect = 0.69,   Method: Composition-based stats.
 Identities = 25/71 (35%), Positives = 30/71 (42%), Gaps = 2/71 (2%)
 Frame = -3

Query: 180 AEEVVVGDLVEVKGGDRVPADLRIISSHGCKVDNSSLTGESEP--QTRSPEFTHENPLET 237
            EE V+G +VEV GGD +  D+    S+   V N  L   S    QT  P F        
Sbjct: 190 GEEAVLGVVVEVDGGDAMSQDVDDTHSYQLTVQNVVLVERSVSLWQTSLPFFG------- 32

Query: 238 RNICFFSTNCV 248
            N C F   CV
Sbjct: 31  -NFCLFYPVCV 2
>17101
          Length = 739

 Score = 29.6 bits (65), Expect = 5.7,   Method: Composition-based stats.
 Identities = 14/27 (51%), Positives = 16/27 (59%)
 Frame = -2

Query: 916 HTAFFASIVVVQWADLIICKTRRNSVF 942
           HT F  S+ VV WADL +C T   S F
Sbjct: 111 HTCFRLSVCVVVWADL*LCITCEYSFF 31
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|30425250|ref|NP_780706.1| actin, beta-like 2 [Mus
musculus]
         (376 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

04742                                                                 729   0.0  
39562                                                                 590   e-169
02757                                                                 284   e-117
12322                                                                 235   2e-62
00608                                                                 187   4e-48
01436                                                                 169   1e-42
11487                                                                  94   2e-40
19721                                                                  96   4e-30
36954                                                                 119   2e-27
32273                                                                 117   1e-26
18926                                                                 107   8e-24
13361                                                                  87   1e-17
17032                                                                  33   0.19 
06132                                                                  30   1.7  
06084                                                                  28   8.0  
>04742
          Length = 2111

 Score =  729 bits (1881), Expect = 0.0,   Method: Compositional matrix adjust.
 Identities = 341/376 (90%), Positives = 361/376 (96%)
 Frame = +2

Query: 1   MVDDELTALVVDNGSGMCKAGFGGDDAPRAVFPSMVGRPRHQGVMVGMGQKDCYVGDEAQ 60
           M D+++ ALV+DNGSGMCKAGF GDDAPRAVFPS+VGRPRHQGVMVGMGQKD YVGDEAQ
Sbjct: 92  MCDEDVAALVIDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQ 271

Query: 61  SKRGILTLKYPIEHGVVTNWDDMEKIWYHTFYNELRVAPDEHPILLTEAPLNPKINREKM 120
           SKRGILTLKYPIEHG+VTNWDDMEKIW+HTFYNELRVAP+EHP+LLTEAPLNPK NREKM
Sbjct: 272 SKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKM 451

Query: 121 TQIMFEAFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHTVPIYEGYALPHAILRLD 180
           TQIMFE FN+PAMYVAIQAVLSLYASGRTTGIV+DSGDGV HTVPIYEGYALPHAI RLD
Sbjct: 452 TQIMFETFNSPAMYVAIQAVLSLYASGRTTGIVLDSGDGVXHTVPIYEGYALPHAISRLD 631

Query: 181 LAGRDLTDYLMKILTERGYNFTTTAEREIVRDVKEKLCYVALDFEQEMVTAAASSSLERS 240
           LAGRDLTDYLMKILTERGY+FTTTAEREIVRD+KEKLCYVALDFEQEM TAA+SSSLE+S
Sbjct: 632 LAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMQTAASSSSLEKS 811

Query: 241 YELPDGQVITIGNERFRCPEAIFQPSFLGIESRGIHETTFNSIMKCDVDIRKDLFANTVL 300
           YELPDGQVITIGNERFRCPEA+FQPSFLG+ES G HETT+NSIMKCDVDIRKDL+ANTVL
Sbjct: 812 YELPDGQVITIGNERFRCPEAMFQPSFLGMESAGXHETTYNSIMKCDVDIRKDLYANTVL 991

Query: 301 SGGSTMYPGIADRMQKEIVTLAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISK 360
           SGGSTMYPGIADRMQKEI  LAP TMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISK
Sbjct: 992 SGGSTMYPGIADRMQKEITALAPPTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISK 1171

Query: 361 QEYDEAGPPIVHRKCF 376
           QEYDE+GP IVHRKCF
Sbjct: 1172QEYDESGPSIVHRKCF 1219
>39562
          Length = 1438

 Score =  590 bits (1520), Expect = e-169,   Method: Compositional matrix adjust.
 Identities = 276/301 (91%), Positives = 293/301 (97%)
 Frame = -2

Query: 76   VVTNWDDMEKIWYHTFYNELRVAPDEHPILLTEAPLNPKINREKMTQIMFEAFNTPAMYV 135
            +VTNWDDMEKIW+HTFYNELRVAP+EHP+LLTEAPLNPK NREKMTQIMFE FN+PAMYV
Sbjct: 1437 IVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNSPAMYV 1258

Query: 136  AIQAVLSLYASGRTTGIVMDSGDGVTHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILT 195
            AIQAVLSLYASGRTTGIV+DSGDGVTHTVPIYEGYALPHAI+RLDLAGRDLTDYLMKILT
Sbjct: 1257 AIQAVLSLYASGRTTGIVLDSGDGVTHTVPIYEGYALPHAIMRLDLAGRDLTDYLMKILT 1078

Query: 196  ERGYNFTTTAEREIVRDVKEKLCYVALDFEQEMVTAAASSSLERSYELPDGQVITIGNER 255
            ERGY+FTTTAEREIVRD+KEKL YVALDFEQEM+TAA+SSSLE+SYELPDGQVITIGNER
Sbjct: 1077 ERGYSFTTTAEREIVRDIKEKLDYVALDFEQEMLTAASSSSLEKSYELPDGQVITIGNER 898

Query: 256  FRCPEAIFQPSFLGIESRGIHETTFNSIMKCDVDIRKDLFANTVLSGGSTMYPGIADRMQ 315
            FRCPEA+FQPSFLG+ES GIHETT+NSIMKCDVDIRKDL+ANTVLSGGSTMYPGIADRMQ
Sbjct: 897  FRCPEAMFQPSFLGMESAGIHETTYNSIMKCDVDIRKDLYANTVLSGGSTMYPGIADRMQ 718

Query: 316  KEIVTLAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDEAGPPIVHRKC 375
            KEI  LAP TMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDE+GP IVHRKC
Sbjct: 717  KEITALAPPTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKC 538

Query: 376  F 376
            F
Sbjct: 537  F 535
>02757
          Length = 1094

 Score =  284 bits (726), Expect(3) = e-117,   Method: Compositional matrix adjust.
 Identities = 134/151 (88%), Positives = 145/151 (96%)
 Frame = -2

Query: 173 PHAILRLDLAGRDLTDYLMKILTERGYNFTTTAEREIVRDVKEKLCYVALDFEQEMVTAA 232
           P AILRLDLAGRDLTDYLMKILTERGY+FTTTAEREIV D+KEKLCYVALDFEQEM TAA
Sbjct: 997 PTAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVXDIKEKLCYVALDFEQEMATAA 818

Query: 233 ASSSLERSYELPDGQVITIGNERFRCPEAIFQPSFLGIESRGIHETTFNSIMKCDVDIRK 292
           +SSSLE+SYELPDGQVITIGNERFRCPE++FQPSFLG+ES GIHETT+NSIMKCDVDIRK
Sbjct: 817 SSSSLEKSYELPDGQVITIGNERFRCPESLFQPSFLGMESAGIHETTYNSIMKCDVDIRK 638

Query: 293 DLFANTVLSGGSTMYPGIADRMQKEIVTLAP 323
           DL+ANTVLSGG+TM+PGIADRMQKEI  LAP
Sbjct: 637 DLYANTVLSGGTTMFPGIADRMQKEITALAP 545

 Score =  108 bits (269), Expect(3) = e-117,   Method: Compositional matrix adjust.
 Identities = 50/53 (94%), Positives = 51/53 (96%)
 Frame = -3

Query: 324 STMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDEAGPPIVHRKCF 376
           STMKIK IAPPERKYSVWIGGSILASLSTFQQMWISKQEYDE+GP IVHRKCF
Sbjct: 543 STMKIKXIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF 385

 Score = 71.2 bits (173), Expect(3) = e-117,   Method: Compositional matrix adjust.
 Identities = 33/34 (97%), Positives = 34/34 (100%)
 Frame = -1

Query: 141  LSLYASGRTTGIVMDSGDGVTHTVPIYEGYALPH 174
            LSLYASGRTTGIV+DSGDGVTHTVPIYEGYALPH
Sbjct: 1094 LSLYASGRTTGIVLDSGDGVTHTVPIYEGYALPH 993
>12322
          Length = 849

 Score =  235 bits (600), Expect = 2e-62,   Method: Compositional matrix adjust.
 Identities = 111/218 (50%), Positives = 151/218 (69%), Gaps = 1/218 (0%)
 Frame = +1

Query: 160 VTHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYNFTTTAEREIVRDVKEKLCY 219
           VTH VP+YEG+A+PH+I+R+D+AGRD+T YL  +L + G +  TTAE E+V+ +KE+ CY
Sbjct: 1   VTHAVPVYEGFAMPHSIMRVDVAGRDVTRYLRLLLRKEGMDLHTTAEFEVVKHIKERTCY 180

Query: 220 VALD-FEQEMVTAAASSSLERSYELPDGQVITIGNERFRCPEAIFQPSFLGIESRGIHET 278
           ++++  ++E V     S     Y LPDG  + +G  RFR PE +F+P  +G E  GIHE 
Sbjct: 181 LSINPLKEESVDTEKVS-----YTLPDGNTVEVGPARFRAPELLFRPDLIGEECEGIHEV 345

Query: 279 TFNSIMKCDVDIRKDLFANTVLSGGSTMYPGIADRMQKEIVTLAPSTMKIKIIAPPERKY 338
              SI K DVD+RK L++N VLSGGST++ G  DR+  E+  LAP  +KI+I AP ER Y
Sbjct: 346 LSYSIQKSDVDLRKTLYSNIVLSGGSTLFKGFGDRLLSELKKLAPKDIKIRISAPQERLY 525

Query: 339 SVWIGGSILASLSTFQQMWISKQEYDEAGPPIVHRKCF 376
           S WIG SILASL TF++MW+SK+EY E G   +HRK F
Sbjct: 526 STWIGXSILASLDTFRKMWVSKREYHEEGVKAIHRKTF 639
>00608
          Length = 1930

 Score =  187 bits (476), Expect = 4e-48,   Method: Compositional matrix adjust.
 Identities = 116/333 (34%), Positives = 178/333 (53%), Gaps = 32/333 (9%)
 Frame = +3

Query: 76  VVTNWDDMEKIWYHTFYNELRVAPDEHPILLTEAPLNPKINREKMTQIMFEAFNTPAMYV 135
           ++ +WD ME+ +    +  LR  P++H  LLTE PLN   NRE   +IMFE+FN P +Y+
Sbjct: 3   IIDDWDLMERFYEQVIFKYLRAEPEDHYFLLTEPPLNTPENREYTAEIMFESFNVPGLYI 182

Query: 136 AIQAVLSLYASGRT--------TGIVMDSGDGVTHTVPIYEGYALPHAILRLDLAGRDLT 187
           A+QAVL+L AS  +        TG V+DSGDGVTH +P+ EGY +   I  + +AGRD+T
Sbjct: 183 AVQAVLALAASWTSRNVGERTLTGTVIDSGDGVTHVIPVAEGYVIGSCIKHIPIAGRDIT 362

Query: 188 DYLMKILTERGYNFTTTAEREIVRDVKEKLCYVALDFEQEMVTAAAS-SSLERSYELPD- 245
            ++ ++L ER          E  + +KE+  YV  D  +E        S   + YE  + 
Sbjct: 363 YFIQQLLREREVGIPPEQSLETAKAIKERFSYVCPDIAKEFSKYDTDPSKWMKKYEGRNT 542

Query: 246 --GQVIT--IGNERFRCPEAIFQPSFLGIE-SRGIHETTFNSIMKCDVDIRKDLFANTVL 300
              Q+ +  +G ERF  PE  F P F   + +  I +   + I  C +D+R+ L+ N VL
Sbjct: 543 ISKQLFSVDVGYERFLGPEIFFHPEFSNPDFTMPISDVVDDVIQNCPIDVRRGLYKNIVL 722

Query: 301 SGGSTMYPGIADRMQKEIV----------------TLAPSTMKIKIIAPPERKYSVWIGG 344
           SGGSTM+     ++Q+++                  + P  +++++I    ++Y+VW GG
Sbjct: 723 SGGSTMFRDFGRKIQRDVKRVVDGRLKASEELSQGRIKPKPIEVQVITHHMQRYAVWFGG 902

Query: 345 SILASLSTFQQMWISKQEYDEAGPPIV-HRKCF 376
           S+LAS   F Q+  +K +YDE GP I  H   F
Sbjct: 903 SMLASTPEFYQVCHTKADYDEHGPSICRHNPVF 1001
>01436
          Length = 2563

 Score =  169 bits (429), Expect = 1e-42,   Method: Compositional matrix adjust.
 Identities = 86/200 (43%), Positives = 121/200 (60%), Gaps = 12/200 (6%)
 Frame = +3

Query: 186 LTDYLMKILTERGYNFTTTAEREIVRDVKEKLCYVALDFEQEMVTAAASSSLERSYELPD 245
           +T YL+K+L  RGY F  +A+ E VR +KEKLCY A D EQE   A  ++ L   Y LPD
Sbjct: 3   ITRYLIKLLLLRGYAFNHSADFETVRMLKEKLCYTAYDVEQEQKLALETTVLVEPYILPD 182

Query: 246 GQVITIGNERFRCPEAIFQPSFLGIESRGIHETTFNSIMKCDVDIRKDLFANTVLSGGST 305
           G+VI +G ERF  PEA+FQP  + ++  G+ E  FN+I   D+DIR D + + VLSGGST
Sbjct: 183 GRVIKVGGERFEAPEALFQPHLINVDGVGVAELLFNTIQAADMDIRPDFYKHIVLSGGST 362

Query: 306 MYPGIADRMQKEIVTL-----------APSTMKIKIIAPPERKYSVWIGGSILAS-LSTF 353
           MYPG+  R+++EI  L             S  KI+I  PP RK+ V++GGS+ A  +   
Sbjct: 363 MYPGLPSRLEREIKQLYLERVLXGDTSRLSKFKIRIEDPPRRKHMVFLGGSVXADIMKDK 542

Query: 354 QQMWISKQEYDEAGPPIVHR 373
              W+ + EY+E G  ++ +
Sbjct: 543 DDFWMMRSEYEEMGVKVLDK 602
>11487
          Length = 771

 Score = 94.0 bits (232), Expect(3) = 2e-40,   Method: Compositional matrix adjust.
 Identities = 41/43 (95%), Positives = 42/43 (97%)
 Frame = -2

Query: 334 PERKYSVWIGGSILASLSTFQQMWISKQEYDEAGPPIVHRKCF 376
           PERKYSVWIGGSILASLSTFQQMWISKQEYDE+GP IVHRKCF
Sbjct: 602 PERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF 474

 Score = 81.6 bits (200), Expect(3) = 2e-40,   Method: Compositional matrix adjust.
 Identities = 36/41 (87%), Positives = 40/41 (97%)
 Frame = -1

Query: 277 ETTFNSIMKCDVDIRKDLFANTVLSGGSTMYPGIADRMQKE 317
           ET +NSIMKCDVDIRKDL+ANTVLSGG+TM+PGIADRMQKE
Sbjct: 771 ETAYNSIMKCDVDIRKDLYANTVLSGGTTMFPGIADRMQKE 649

 Score = 28.5 bits (62), Expect(3) = 2e-40,   Method: Compositional matrix adjust.
 Identities = 13/18 (72%), Positives = 14/18 (77%)
 Frame = -3

Query: 316 KEIVTLAPSTMKIKIIAP 333
           + I  LAP TMKIKIIAP
Sbjct: 655 ERITALAPPTMKIKIIAP 602
>19721
          Length = 757

 Score = 96.3 bits (238), Expect(2) = 4e-30,   Method: Compositional matrix adjust.
 Identities = 56/120 (46%), Positives = 75/120 (62%), Gaps = 8/120 (6%)
 Frame = +2

Query: 76  VVTNWDDMEKIWYHTFYNELRVAPDEHPILLTEAPLNPKINREKMTQIMFEAFNTPAMYV 135
           VV +WD  E+      +  LR  P++H  LLTE PLN   NRE   +IMFE FN P +Y+
Sbjct: 2   VVEDWDLHERFMEQAIFKYLRAEPEDHYFLLTEPPLNTPENREFTAEIMFETFNIPGLYI 181

Query: 136 AIQAVLSLYASGRT--------TGIVMDSGDGVTHTVPIYEGYALPHAILRLDLAGRDLT 187
           A+QAVL+L AS  +        TG V+DSGDGVTH +P+ +GY +  AI  + +AGRD+T
Sbjct: 182 AVQAVLALAASWTSRPPNERTLTGTVIDSGDGVTHVIPVVDGYVIGSAIKHIPIAGRDIT 361

 Score = 53.1 bits (126), Expect(2) = 4e-30,   Method: Compositional matrix adjust.
 Identities = 33/108 (30%), Positives = 51/108 (47%), Gaps = 8/108 (7%)
 Frame = +3

Query: 208 EIVRDVKEKLCYVALDFEQEMVTAAA-------SSSLERSYELPDGQVITIGNERFRCPE 260
           E  + +KE+  YV  D  +E     +       +  +  S + PD     +G E+F  PE
Sbjct: 420 EAAKQIKERYSYVCPDIAKEFAKYDSDPEKWIKAHKMSGSSKYPDFS-FDVGYEKFLGPE 596

Query: 261 AIFQPSFL-GIESRGIHETTFNSIMKCDVDIRKDLFANTVLSGGSTMY 307
             F+P F+ G     I +     I  C +D R+ L+ N VLSGGS+M+
Sbjct: 597 VFFRPEFVNGDFQASISDVVDTVIQSCPIDSRRPLYNNIVLSGGSSMF 740
>36954
          Length = 892

 Score =  119 bits (298), Expect = 2e-27,   Method: Compositional matrix adjust.
 Identities = 65/189 (34%), Positives = 104/189 (55%), Gaps = 9/189 (4%)
 Frame = -1

Query: 4   DELTALVVDNGSGMCKAGFGGDDAPRAVFPSMVGRPRHQGVMVGMGQKDCYVGDEAQSKR 63
           DE+ ALV D GS   +AG+ G+D P+A  P+ VG        +     D     E +   
Sbjct: 817 DEVGALVFDIGSYSFRAGYAGEDTPKAEIPTHVGVMEDIETTMDTDGGDAPPQPEKKYLI 638

Query: 64  GILTLKYP---------IEHGVVTNWDDMEKIWYHTFYNELRVAPDEHPILLTEAPLNPK 114
             + +K+P         ++ G+V +WD  EK+  + +   ++     HP+L++E   N K
Sbjct: 637 DTVYMKHPRKGMHLNSFLKDGMVEDWDMFEKVIDYAYNRSIKSESCLHPLLMSEPAWNTK 458

Query: 115 INREKMTQIMFEAFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHTVPIYEGYALPH 174
             REK+T+IMFE +N PA ++   +VLS +A+GR+T +++DSG   T  VP+Y+GY L  
Sbjct: 457 AKREKLTEIMFEKYNIPAFFLRKNSVLSAFANGRSTALILDSGATHTSAVPVYDGYVLTQ 278

Query: 175 AILRLDLAG 183
            I++  LAG
Sbjct: 277 GIVKSPLAG 251
>32273
          Length = 265

 Score =  117 bits (292), Expect = 1e-26,   Method: Compositional matrix adjust.
 Identities = 47/88 (53%), Positives = 73/88 (82%), Gaps = 1/88 (1%)
 Frame = -2

Query: 65  ILTLKYPIEHGVVTNWDDMEKIWYHTF-YNELRVAPDEHPILLTEAPLNPKINREKMTQI 123
           +++++YP+EHG+V +W+DME+IW + +  ++L+   +EHP+LLTEAPLNP+ NREK  +I
Sbjct: 264 LMSIRYPMEHGIVKDWNDMERIWQYIYSKDQLQTFSEEHPVLLTEAPLNPRRNREKAAEI 85

Query: 124 MFEAFNTPAMYVAIQAVLSLYASGRTTG 151
            F+ FN PA+++++QAVLSLYA+GR TG
Sbjct: 84  FFDTFNVPALFISMQAVLSLYATGRITG 1
>18926
          Length = 478

 Score =  107 bits (267), Expect = 8e-24,   Method: Compositional matrix adjust.
 Identities = 47/105 (44%), Positives = 68/105 (64%), Gaps = 3/105 (2%)
 Frame = +1

Query: 274 GIHETTFNSIMKCDVDIRKDLFANTVLSGGSTMYPGIADRMQKEIVTLAPSTMKIKIIAP 333
           G+      S+  CD+DIR  L+   +  GG+++  G  +R+ +++    P +M++KIIA 
Sbjct: 97  GVGHVVTTSVGMCDIDIRPSLYGGVIAVGGNSLIQGFTERLNRDLSNKTPPSMRLKIIAA 276

Query: 334 P---ERKYSVWIGGSILASLSTFQQMWISKQEYDEAGPPIVHRKC 375
               ER++S WIGGSILASL +FQQMW+SKQEY+E G   V RKC
Sbjct: 277 ASTAERRFSSWIGGSILASLGSFQQMWVSKQEYEEGGKSCVERKC 411
>13361
          Length = 1217

 Score = 87.0 bits (214), Expect = 1e-17,   Method: Compositional matrix adjust.
 Identities = 54/176 (30%), Positives = 83/176 (47%), Gaps = 23/176 (13%)
 Frame = +3

Query: 218 CYVALDFEQEMVTA-AASSSLERSYE-----LPDGQVITIGNERFRCPEAIFQPSFLGIE 271
           CY+  D  +E     +  S   R+Y            + +G ERF  PE  F P F   +
Sbjct: 42  CYICPDIAKEFAKYDSEPSKWIRNYTGMNTVTKQAFNVDVGYERFLGPEIFFHPEFSNPD 221

Query: 272 -SRGIHETTFNSIMKCDVDIRKDLFANTVLSGGSTMYPGIADRMQKEIV----------- 319
            +  + E   N I  C +D+R+ L+ N VLSGGSTM+     R+Q++I            
Sbjct: 222 FTIPLSEIVDNVIQNCPIDVRRHLYNNIVLSGGSTMFKDFGRRLQRDIKRSVDTRLRISE 401

Query: 320 -----TLAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDEAGPPI 370
                 + P  + +++I    ++Y+VW GGS+LAS   F Q+  +K  Y+E GP I
Sbjct: 402 NLSEGRIKPKPIDVQVITHHMQRYAVWFGGSMLASTPEFYQVCHTKAAYEEYGPSI 569
>17032
          Length = 2938

 Score = 33.1 bits (74), Expect = 0.19,   Method: Compositional matrix adjust.
 Identities = 15/30 (50%), Positives = 19/30 (63%)
 Frame = -1

Query: 342  IGGSILASLSTFQQMWISKQEYDEAGPPIV 371
             GGS+LAS   F Q+  +K +YDE GP I 
Sbjct: 2938 FGGSMLASTPEFYQVCHTKADYDEHGPSIC 2849
>06132
          Length = 1490

 Score = 30.0 bits (66), Expect = 1.7,   Method: Compositional matrix adjust.
 Identities = 21/67 (31%), Positives = 29/67 (43%), Gaps = 7/67 (10%)
 Frame = -2

Query: 221  ALDFEQEMVTAAASSSLERSYELPDGQVITIGNERFRCPEAIFQPSF-------LGIESR 273
            AL F+Q M T    +S  R Y  P+ + +T+G      P    Q  +       LG+   
Sbjct: 1015 ALLFQQLMCTTLEKNSHHRLYVSPNHRKLTLGCPVLMLPHDARQDMY*NANCYVLGMTQL 836

Query: 274  GIHETTF 280
            GI  TTF
Sbjct: 835  GIELTTF 815
>06084
          Length = 1739

 Score = 27.7 bits (60), Expect = 8.0,   Method: Compositional matrix adjust.
 Identities = 13/31 (41%), Positives = 18/31 (58%), Gaps = 2/31 (6%)
 Frame = +3

Query: 323 PSTMKIKIIA--PPERKYSVWIGGSILASLS 351
           PS +  +  +   P+RKY VW+ G I  SLS
Sbjct: 942 PSNLSTQFYSQYKPQRKYGVWVRGGITRSLS 1034
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31981828|ref|NP_034068.2| coatomer protein complex
subunit alpha [Mus musculus]
         (1224 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

10824                                                                 569   0.0  
28855                                                                  83   5e-23
30256                                                                  86   7e-17
02147                                                                  75   1e-13
19949                                                                  74   5e-13
27465                                                                  72   1e-12
12806                                                                  68   2e-11
13335                                                                  68   2e-11
17598                                                                  66   9e-11
00561                                                                  65   2e-10
12574                                                                  64   6e-10
26939                                                                  61   3e-09
37180                                                                  60   4e-09
01327                                                                  59   1e-08
17602                                                                  57   5e-08
21105                                                                  55   1e-07
03156                                                                  55   1e-07
03387                                                                  55   2e-07
27806                                                                  54   3e-07
15118                                                                  50   5e-06
19498                                                                  49   8e-06
12960                                                                  49   2e-05
14555                                                                  38   2e-05
20662                                                                  47   6e-05
19863                                                                  47   7e-05
18981                                                                  45   1e-04
01462                                                                  44   5e-04
02960                                                                  42   0.001
21763                                                                  42   0.001
19140                                                                  42   0.001
03395                                                                  42   0.001
01768                                                                  42   0.002
13278                                                                  42   0.002
00825                                                                  41   0.003
01805                                                                  41   0.003
15780                                                                  40   0.004
21960                                                                  40   0.007
16199                                                                  39   0.016
17266                                                                  38   0.019
20271                                                                  38   0.020
14500                                                                  38   0.032
16105                                                                  37   0.038
33180                                                                  33   0.092
02090                                                                  35   0.13 
26107                                                                  35   0.13 
21921                                                                  35   0.13 
17298                                                                  35   0.15 
04358                                                                  35   0.16 
28403                                                                  35   0.24 
15337                                                                  35   0.27 
04524                                                                  34   0.38 
31474                                                                  33   0.57 
10264                                                                  33   0.60 
31864                                                                  33   0.99 
10162                                                                  32   1.1  
06576                                                                  32   1.1  
05493                                                                  32   1.4  
31054                                                                  32   1.8  
12140                                                                  32   1.8  
38177                                                                  32   2.3  
04088                                                                  31   2.8  
01598                                                                  31   3.2  
36111                                                                  31   3.4  
13509                                                                  30   4.0  
25880                                                                  30   4.9  
01249                                                                  30   7.1  
07781                                                                  30   7.1  
30297                                                                  30   7.7  
11915                                                                  29   9.8  
>10824
          Length = 1751

 Score =  569 bits (1466), Expect(2) = 0.0,   Method: Compositional matrix adjust.
 Identities = 277/390 (71%), Positives = 315/390 (80%), Gaps = 1/390 (0%)
 Frame = -3

Query: 836  DIDTVGTEGWGEDAELQLDEDGFVEAPEGLGEDVLGKGQEEGGGWXXXXXXXXXXXXXXX 895
            D   V   GWG DAEL LDEDG   A EG  E+ +  G  EGG W               
Sbjct: 1458 DWRMVQERGWGADAELVLDEDGGFGA-EGFEEEGVTGGDAEGGAWDVEDEDLELPPDLDV 1282

Query: 896  SGV-SGSAEDGFFVPPTKGTSPTQIWCNNSQLPVDHILAGSFETAMRLLHDQVGVIQFGP 954
                +G+ E+G+FVPPTKGTS  Q+WCNNSQLPVDH+LAGSFETAMRLLHDQVGV+QF  
Sbjct: 1281 GATATGAGEEGYFVPPTKGTSQAQVWCNNSQLPVDHVLAGSFETAMRLLHDQVGVVQFDQ 1102

Query: 955  YKQLFLQTYARGRTTYQALPCLPSMYSYPNRNWKDAGLKNGVPAVGLKLNDLIQRLQLCY 1014
            YKQLFLQTY+R RT+Y  LP LP ++ +P+RNWK+AG ++G+PAVG+KLN L+Q+LQ  Y
Sbjct: 1101 YKQLFLQTYSRARTSYLGLPSLPPLFGFPHRNWKEAGGRSGMPAVGMKLNTLVQQLQTAY 922

Query: 1015 QLTTVGKFEEAVEKFRSILLSVPLLVVDNKQEIAEAQQLITICREYIVGLCMEIERKKLP 1074
            QLTT GKF EA ++FRSILLSVPLLVVD+KQEIAEAQQLI ICREYI+GL ME +RK+LP
Sbjct: 921  QLTTTGKFAEAGDRFRSILLSVPLLVVDSKQEIAEAQQLIEICREYILGLHMESKRKELP 742

Query: 1075 KETLDQQKRICEMAAYFTHSNLQPVHMILVLRTALNLFFKLKNFKTAATFARRLLELGPK 1134
            K TLDQQKR CEMAAYFTH NLQPVHMIL LRTALNLFFKLKNFKTAA+FARRLLELGPK
Sbjct: 741  KGTLDQQKRQCEMAAYFTHCNLQPVHMILTLRTALNLFFKLKNFKTAASFARRLLELGPK 562

Query: 1135 PEVAQQTRKILSACEKNPTDACQLNYDMHNPFDICAASYRPIYRGKPVEKCPLSGACYSP 1194
            PEVAQQTRKIL+ACEKNPTD  +L YD HNPFD+CAAS+ PIYRGKPV KCPLSGACY P
Sbjct: 561  PEVAQQTRKILAACEKNPTDEHELKYDQHNPFDVCAASFVPIYRGKPVVKCPLSGACYLP 382

Query: 1195 EFKGQICRVTTVTEIGKDVIGLRISPLQFR 1224
            E+KG++C ++ VTEIGKD IGLRIS LQFR
Sbjct: 381  EYKGEVCXISKVTEIGKDCIGLRISTLQFR 292

 Score =  121 bits (303), Expect(2) = 0.0,   Method: Composition-based stats.
 Identities = 66/98 (67%), Positives = 81/98 (82%)
 Frame = -2

Query: 739  LGDVSERVRILKNYGQKSLAYLSAATHGLDEEAESLKETFDPEKETIPDIDPNAKLLQPP 798
            LGDV ERV+ILKN GQKSLAYL+AATHGL EEAE LKE+F  E+E +PD+ P A+LLQPP
Sbjct: 1750 LGDVPERVKILKNCGQKSLAYLTAATHGLQEEAEELKESFG-EEEKVPDLYPGARLLQPP 1574

Query: 799  APIMPLDTNWPLLTVSKGFFEGSIASKGKGGALAADID 836
             P+   + NWPLLTVSKGFFEG++A++GK  ALAA ++
Sbjct: 1573 PPLCLQEQNWPLLTVSKGFFEGAMAARGKPSALAAAVE 1460
>28855
          Length = 370

 Score = 83.2 bits (204), Expect(2) = 5e-23,   Method: Composition-based stats.
 Identities = 35/45 (77%), Positives = 38/45 (84%)
 Frame = +2

Query: 905 GFFVPPTKGTSPTQIWCNNSQLPVDHILAGSFETAMRLLHDQVGV 949
           G    P +GTS  Q+WCNNSQLPVDH+LAGSFETAMRLLHDQVGV
Sbjct: 158 GLLRSPNQGTSQAQVWCNNSQLPVDHVLAGSFETAMRLLHDQVGV 292

 Score = 44.3 bits (103), Expect(2) = 5e-23,   Method: Composition-based stats.
 Identities = 18/27 (66%), Positives = 21/27 (77%)
 Frame = +1

Query: 948 GVIQFGPYKQLFLQTYARGRTTYQALP 974
           G +QF  YKQLFLQTY+R RT+Y  LP
Sbjct: 286 GGVQFDQYKQLFLQTYSRARTSYLGLP 366
>30256
          Length = 961

 Score = 86.3 bits (212), Expect = 7e-17,   Method: Composition-based stats.
 Identities = 65/221 (29%), Positives = 94/221 (42%)
 Frame = +3

Query: 67  VSGGDDYKIKVWNYKLRRCLFTLLGHLDYIRTTFFHHEYPWILSASDDQTIRVWNWQSRT 126
           +SG  D  +KVWN     C  TL GH   +R      +   ++S S D T+RVW+ +S  
Sbjct: 84  ISGSTDRSLKVWNADTGVCTHTLYGHSSTVRCLSLSGKK--VVSGSRDATLRVWDIESGH 257

Query: 127 CVCVLTGHNHYVMCAQFHPSEDLVVSASLDQTVRVWDISGLRKKNLSPGAVESDVRGITG 186
           C+ VL GH   V C Q+      VVS + D TVRVWD                       
Sbjct: 258 CLNVLLGHMAAVRCVQYDGKR--VVSGAXDYTVRVWD----------------------- 362

Query: 187 VDLFGTTDAVVKHVLEGHDRGVNWAAFHPTMPLIVSGADDRQVKIWRMNESKAWEVDTCR 246
                   A   H L+GH   V    F      +VSG+ D  +++W +   K   V T  
Sbjct: 363 -----PDTASCLHTLQGHTNRVYSLQFDGVY--VVSGSLDTSIRVWDVRCGKL--VHTLM 515

Query: 247 GHYNNVSCAVFHPRQELILSNSEDKSIRVWDMSKRTGVQTF 287
           GH +  S      +  L++S + D +++VWD+     +QT 
Sbjct: 516 GHQSLTSG--LELKDNLLVSGNADSTVKVWDVHTGKCLQTL 632

 Score = 50.8 bits (120), Expect = 3e-06,   Method: Composition-based stats.
 Identities = 33/123 (26%), Positives = 60/123 (48%), Gaps = 3/123 (2%)
 Frame = +3

Query: 2   LTKFETKSARVKGLSFHPKRPWILTSLHNGVIQLWDYRMCTLIDKFDEHDGPVRGIDFHK 61
           L   +  + RV  L F     ++++   +  I++WD R   L+     H     G++   
Sbjct: 381 LHTLQGHTNRVYSLQF--DGVYVVSGSLDTSIRVWDVRCGKLVHTLMGHQSLTSGLEL-- 548

Query: 62  QQPLFVSGGDDYKIKVWNYKLRRCLFTLLG---HLDYIRTTFFHHEYPWILSASDDQTIR 118
           +  L VSG  D  +KVW+    +CL TLLG   H   +    F+ ++  +++ SDD T++
Sbjct: 549 KDNLLVSGNADSTVKVWDVHTGKCLQTLLGPNKHRSAVTCLQFNKKF--VVTCSDDGTVK 722

Query: 119 VWN 121
           +W+
Sbjct: 723 LWD 731
>02147
          Length = 1547

 Score = 75.5 bits (184), Expect = 1e-13,   Method: Compositional matrix adjust.
 Identities = 56/249 (22%), Positives = 111/249 (44%), Gaps = 13/249 (5%)
 Frame = +2

Query: 44  IDKFDEHDGPVRGIDFHKQQPLFVSGGDDYKIKVWNYKLRRCLFTLLGHLDYIRTTFFHH 103
           I  F+ H G V G   +++     +G  D+  K+W+ +    L T   H   +++  F H
Sbjct: 152 IGTFEGHKGAVWGATLNREATRAATGAADFSAKIWDAEKGEELQTF-SHKHIVKSVDFSH 328

Query: 104 EYPWILSASDDQTIRVWNW-QSRTCVCVLTGHNHYVMCAQFHPSEDLVVSASLDQTVRVW 162
           +   +L+ S+++ ++V++   +        GH   +  A F      ++SAS D+TVR+W
Sbjct: 329 DGTALLTGSNEKLLKVFDLVNTDAEPKSFAGHTSNIKGALFLSDGKRIISASDDKTVRLW 508

Query: 163 DISGLRKK------------NLSPGAVESDVRGITGVDLFGTTDAVVKHVLEGHDRGVNW 210
            +   ++              LSP      V     +  +   D + +      +  ++ 
Sbjct: 509 SLETCQEVQQLTFDTPPTSLTLSPDKNTIIVTHSQNIAFY-QADTLREMKKFEAEAPISS 685

Query: 211 AAFHPTMPLIVSGADDRQVKIWRMNESKAWEVDTCRGHYNNVSCAVFHPRQELILSNSED 270
           A+ H +    V+G +D   K+++ +     E+++ +GH+  V C  F P  EL  S SED
Sbjct: 686 ASLHQSERFFVAGGED--FKMYKFDYETGKEIESFKGHFGPVHCVRFSPDGELYASGSED 859

Query: 271 KSIRVWDMS 279
            ++R+W  +
Sbjct: 860 GTLRLWQTT 886

 Score = 47.8 bits (112), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 26/107 (24%), Positives = 52/107 (48%)
 Frame = +2

Query: 15  LSFHPKRPWILTSLHNGVIQLWDYRMCTLIDKFDEHDGPVRGIDFHKQQPLFVSGGDDYK 74
           L+  P +  I+ + H+  I  +       + KF E + P+     H+ +  FV+GG+D+K
Sbjct: 566 LTLSPDKNTIIVT-HSQNIAFYQADTLREMKKF-EAEAPISSASLHQSERFFVAGGEDFK 739

Query: 75  IKVWNYKLRRCLFTLLGHLDYIRTTFFHHEYPWILSASDDQTIRVWN 121
           +  ++Y+  + + +  GH   +    F  +     S S+D T+R+W 
Sbjct: 740 MYKFDYETGKEIESFKGHFGPVHCVRFSPDGELYASGSEDGTLRLWQ 880

 Score = 43.9 bits (102), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 53/238 (22%), Positives = 105/238 (44%), Gaps = 21/238 (8%)
 Frame = +2

Query: 220 IVSGADDRQVKIWRMNESKAWEVDTCRGHYNNVSCAVFHPRQELILSNSEDKSIRVWDMS 279
           +++G++++ +K++ +  + A E  +  GH +N+  A+F    + I+S S+DK++R+W + 
Sbjct: 341 LLTGSNEKLLKVFDLVNTDA-EPKSFAGHTSNIKGALFLSDGKRIISASDDKTVRLWSLE 517

Query: 280 KRTGVQTFRRDH---------DRFWVLAAHP-NLNLFAAGHDGGMIVFKLERERPAYAVH 329
               VQ    D          D+  ++  H  N+  + A     M  F+ E    + ++H
Sbjct: 518 TCQEVQQLTFDTPPTSLTLSPDKNTIIVTHSQNIAFYQADTLREMKKFEAEAPISSASLH 697

Query: 330 GNMLHYV---KDRFLRQLDFNSSKDVAVMQLRSSSKFPVFNMSYNPAENAVLLCTRASNL 386
            +   +V   +D  + + D+ + K++   +       PV  + ++P        +    L
Sbjct: 698 QSERFFVAGGEDFKMYKFDYETGKEIESFKGHFG---PVHCVRFSPDGELYASGSEDGTL 868

Query: 387 E------NSTYDLY--TIPKDADSQNPDAPEGKRSSGLTAVWVARNRFAVLDRMHSLL 436
                    TY L+   IP +AD+QN   P+ K  S  T     R+      R+HS L
Sbjct: 869 RLWQTTIGRTYGLWKCVIPDEADAQNS-TPDVKAES*WTGR-SDRDVXTAHTRLHSGL 1036

 Score = 38.5 bits (88), Expect = 0.017,   Method: Compositional matrix adjust.
 Identities = 21/84 (25%), Positives = 37/84 (44%)
 Frame = +2

Query: 2   LTKFETKSARVKGLSFHPKRPWILTSLHNGVIQLWDYRMCTLIDKFDEHDGPVRGIDFHK 61
           + KFE + A +   S H    + +    +  +  +DY     I+ F  H GPV  + F  
Sbjct: 650 MKKFEAE-APISSASLHQSERFFVAGGEDFKMYKFDYETGKEIESFKGHFGPVHCVRFSP 826

Query: 62  QQPLFVSGGDDYKIKVWNYKLRRC 85
              L+ SG +D  +++W   + R 
Sbjct: 827 DGELYASGSEDGTLRLWQTTIGRT 898

 Score = 31.2 bits (69), Expect = 2.4,   Method: Compositional matrix adjust.
 Identities = 23/91 (25%), Positives = 37/91 (40%), Gaps = 3/91 (3%)
 Frame = +2

Query: 242 VDTCRGHYNNVSCAVFHPRQELILSNSEDKSIRVWDMSKRTGVQTFRRDHDRFWVLAAHP 301
           + T  GH   V  A  +       + + D S ++WD  K   +QTF   H    V  +H 
Sbjct: 152 IGTFEGHKGAVWGATLNREATRAATGAADFSAKIWDAEKGEELQTFSHKHIVKSVDFSHD 331

Query: 302 NLNLFAAGHDGGMIVFKL---ERERPAYAVH 329
              L    ++  + VF L   + E  ++A H
Sbjct: 332 GTALLTGSNEKLLKVFDLVNTDAEPKSFAGH 424

 Score = 30.8 bits (68), Expect = 3.5,   Method: Composition-based stats.
 Identities = 13/34 (38%), Positives = 18/34 (52%)
 Frame = -3

Query: 1169 CAASYRPIYRGKPVEKCPLSGACYSPEFKGQICR 1202
            C  S RP+  G+P  K    G+CY+P  K  + R
Sbjct: 1158 CRHSGRPLPGGRPFNKLLSCGSCYTPVVKRHLSR 1057
>19949
          Length = 903

 Score = 73.6 bits (179), Expect = 5e-13,   Method: Compositional matrix adjust.
 Identities = 36/111 (32%), Positives = 59/111 (53%)
 Frame = +2

Query: 54  VRGIDFHKQQPLFVSGGDDYKIKVWNYKLRRCLFTLLGHLDYIRTTFFHHEYPWILSASD 113
           V+ +DFH       SG  D  +K+W+ + + C++T  GH   +    F  +  WI SAS+
Sbjct: 2   VKSLDFHPYGAYTASGSMDCNVKLWDIRRKGCIYTYKGHTGCVCCLRFSPDGRWIASASE 181

Query: 114 DQTIRVWNWQSRTCVCVLTGHNHYVMCAQFHPSEDLVVSASLDQTVRVWDI 164
           D  +++W+  +   +  L  H   V   +FHP E L+ S S D+TV+ WD+
Sbjct: 182 DGLVKLWDLTAGKLLTDLKLHRDAVNTIEFHPHEFLLASGSADRTVKFWDL 334

 Score = 65.5 bits (158), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 46/175 (26%), Positives = 75/175 (42%)
 Frame = +2

Query: 96  IRTTFFHHEYPWILSASDDQTIRVWNWQSRTCVCVLTGHNHYVMCAQFHPSEDLVVSASL 155
           +++  FH    +  S S D  +++W+ + + C+    GH   V C +F P    + SAS 
Sbjct: 2   VKSLDFHPYGAYTASGSMDCNVKLWDIRRKGCIYTYKGHTGCVCCLRFSPDGRWIASASE 181

Query: 156 DQTVRVWDISGLRKKNLSPGAVESDVRGITGVDLFGTTDAVVKHVLEGHDRGVNWAAFHP 215
           D  V++WD        L+ G + +D                    L+ H   VN   FHP
Sbjct: 182 DGLVKLWD--------LTAGKLLTD--------------------LKLHRDAVNTIEFHP 277

Query: 216 TMPLIVSGADDRQVKIWRMNESKAWEVDTCRGHYNNVSCAVFHPRQELILSNSED 270
              L+ SG+ DR VK W +   +   + T     N++   +FHP    + S S+D
Sbjct: 278 HEFLLASGSADRTVKFWDLETFQL--ISTTEPEANSIRSILFHPDGVCLYSGSKD 436

 Score = 57.0 bits (136), Expect = 4e-08,   Method: Compositional matrix adjust.
 Identities = 41/152 (26%), Positives = 69/152 (45%), Gaps = 1/152 (0%)
 Frame = +2

Query: 12  VKGLSFHPKRPWILTSLHNGVIQLWDYRMCTLIDKFDEHDGPVRGIDFHKQQPLFVSGGD 71
           VK L FHP   +  +   +  ++LWD R    I  +  H G V  + F        S  +
Sbjct: 2   VKSLDFHPYGAYTASGSMDCNVKLWDIRRKGCIYTYKGHTGCVCCLRFSPDGRWIASASE 181

Query: 72  DYKIKVWNYKLRRCLFTLLGHLDYIRTTFFH-HEYPWILSASDDQTIRVWNWQSRTCVCV 130
           D  +K+W+    + L  L  H D + T  FH HE+  + S S D+T++ W+ ++   +  
Sbjct: 182 DGLVKLWDLTAGKLLTDLKLHRDAVNTIEFHPHEF-LLASGSADRTVKFWDLETFQLIST 358

Query: 131 LTGHNHYVMCAQFHPSEDLVVSASLDQTVRVW 162
                + +    FHP    + S S D T++V+
Sbjct: 359 TEPEANSIRSILFHPDGVCLYSGSKD-TLKVY 451

 Score = 52.4 bits (124), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 43/183 (23%), Positives = 73/183 (39%)
 Frame = +2

Query: 138 VMCAQFHPSEDLVVSASLDQTVRVWDISGLRKKNLSPGAVESDVRGITGVDLFGTTDAVV 197
           V    FHP      S S+D  V++WDI   R+K    G +                    
Sbjct: 2   VKSLDFHPYGAYTASGSMDCNVKLWDI---RRK----GCI-------------------- 100

Query: 198 KHVLEGHDRGVNWAAFHPTMPLIVSGADDRQVKIWRMNESKAWEVDTCRGHYNNVSCAVF 257
            +  +GH   V    F P    I S ++D  VK+W +   K   +   + H + V+   F
Sbjct: 101 -YTYKGHTGCVCCLRFSPDGRWIASASEDGLVKLWDLTAGKL--LTDLKLHRDAVNTIEF 271

Query: 258 HPRQELILSNSEDKSIRVWDMSKRTGVQTFRRDHDRFWVLAAHPNLNLFAAGHDGGMIVF 317
           HP + L+ S S D++++ WD+     + T   + +    +  HP+     +G    + V+
Sbjct: 272 HPHEFLLASGSADRTVKFWDLETFQLISTTEPEANSIRSILFHPDGVCLYSGSKDTLKVY 451

Query: 318 KLE 320
             E
Sbjct: 452 HWE 460

 Score = 32.3 bits (72), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 19/81 (23%), Positives = 34/81 (41%)
 Frame = +2

Query: 1   MLTKFETKSARVKGLSFHPKRPWILTSLHNGVIQLWDYRMCTLIDKFDEHDGPVRGIDFH 60
           +LT  +     V  + FHP    + +   +  ++ WD     LI   +     +R I FH
Sbjct: 221 LLTDLKLHRDAVNTIEFHPHEFLLASGSADRTVKFWDLETFQLISTTEPEANSIRSILFH 400

Query: 61  KQQPLFVSGGDDYKIKVWNYK 81
                  SG  D  +KV++++
Sbjct: 401 PDGVCLYSGSKD-TLKVYHWE 460
>27465
          Length = 658

 Score = 72.0 bits (175), Expect = 1e-12,   Method: Compositional matrix adjust.
 Identities = 34/121 (28%), Positives = 63/121 (52%), Gaps = 1/121 (0%)
 Frame = -1

Query: 50  HDGPVRGIDFHKQQPLFVSGGDDYKIKVWNYKLRRCLFTLLGHLDYIRTTFFHHEY-PWI 108
           H  P+  + F+K    F++G  D   K+W+      L TL GH + +    F++ +   +
Sbjct: 364 HILPLTNVAFNKSGSSFITGSYDRTCKIWDTASAEELHTLEGHRNVVYAIAFNNPFGDKV 185

Query: 109 LSASDDQTIRVWNWQSRTCVCVLTGHNHYVMCAQFHPSEDLVVSASLDQTVRVWDISGLR 168
           ++ S D+T ++W+     C   L GH   ++C  F+PS  L+ + S+D T R+WD+   +
Sbjct: 184 ITGSFDKTCKLWSTADGKCYHTLRGHTAEIVCVSFNPSSTLIATGSMDTTCRLWDVEKAQ 5

Query: 169 K 169
           +
Sbjct: 4   R 2

 Score = 59.3 bits (142), Expect = 9e-09,   Method: Compositional matrix adjust.
 Identities = 41/152 (26%), Positives = 63/152 (41%), Gaps = 1/152 (0%)
 Frame = -1

Query: 130 VLTGHNHYVMCAQFHPSEDLVVSASLDQTVRVWDISGLRKKNLSPGAVESDVRGITGVDL 189
           VL  H   +    F+ S    ++ S D+T ++WD                          
Sbjct: 376 VLRAHILPLTNVAFNKSGSSFITGSYDRTCKIWD-------------------------- 275

Query: 190 FGTTDAVVKHVLEGHDRGVNWAAFH-PTMPLIVSGADDRQVKIWRMNESKAWEVDTCRGH 248
             T  A   H LEGH   V   AF+ P    +++G+ D+  K+W   + K +   T RGH
Sbjct: 274 --TASAEELHTLEGHRNVVYAIAFNNPFGDKVITGSFDKTCKLWSTADGKCYH--TLRGH 107

Query: 249 YNNVSCAVFHPRQELILSNSEDKSIRVWDMSK 280
              + C  F+P   LI + S D + R+WD+ K
Sbjct: 106 TAEIVCVSFNPSSTLIATGSMDTTCRLWDVEK 11

 Score = 50.1 bits (118), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 38/175 (21%), Positives = 71/175 (40%), Gaps = 11/175 (6%)
 Frame = -1

Query: 75  IKVWNYKLRRC---------LFTLL-GHLDYIRTTFFHHEYPWILSASDDQTIRVWNWQS 124
           +K W +  R+          LF +L  H+  +    F+      ++ S D+T ++W+  S
Sbjct: 445 VKNWCFACRKTRPKDDHHFYLFKVLRAHILPLTNVAFNKSGSSFITGSYDRTCKIWDTAS 266

Query: 125 RTCVCVLTGHNHYVMCAQF-HPSEDLVVSASLDQTVRVWDISGLRKKNLSPGAVESDVRG 183
              +  L GH + V    F +P  D V++ S D+T ++W                     
Sbjct: 265 AEELHTLEGHRNVVYAIAFNNPFGDKVITGSFDKTCKLW--------------------- 149

Query: 184 ITGVDLFGTTDAVVKHVLEGHDRGVNWAAFHPTMPLIVSGADDRQVKIWRMNESK 238
                   T D    H L GH   +   +F+P+  LI +G+ D   ++W + +++
Sbjct: 148 -------STADGKCYHTLRGHTAEIVCVSFNPSSTLIATGSMDTTCRLWDVEKAQ 5
>12806
          Length = 961

 Score = 68.2 bits (165), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 41/158 (25%), Positives = 73/158 (46%), Gaps = 4/158 (2%)
 Frame = +3

Query: 12  VKGLSFHPKRPWILTSLHNGVIQLWDYRMCTLIDKFDEHDGPVRGIDFHKQQPLFVSGGD 71
           +  L+      + L+S  +  ++LWD +  +   +F  H   V  + F        SGG 
Sbjct: 174 ISDLALSADSRFALSSSWDATLRLWDIKKGSTTSRFINHTRDVLTVAFSPDNRQIASGGR 353

Query: 72  DYKIKVWNYKLRRCLFTL--LGHLDYIRTTFFHHEY--PWILSASDDQTIRVWNWQSRTC 127
           D  +K+WN  +  C +T+    H D++    FH +   P ++SAS+D+TI+VW+  + T 
Sbjct: 354 DKNLKIWNI-MGECKYTVDANAHTDWVTCVRFHQDTKNPIVVSASNDKTIKVWDNHTMTL 530

Query: 128 VCVLTGHNHYVMCAQFHPSEDLVVSASLDQTVRVWDIS 165
                GH   +       S + +VS S D     W+++
Sbjct: 531 KNTFVGHKAQITALDM--STNYLVSGSKDGIAMTWNVA 638

 Score = 55.1 bits (131), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 41/182 (22%), Positives = 70/182 (38%), Gaps = 12/182 (6%)
 Frame = +3

Query: 63  QPLFVSGGDDYKIKVWNYKLRR----------CLFTLLGHLDYIRTTFFHHEYPWILSAS 112
           +P  +SGG D  I VW+   ++             TL GH  +I       +  + LS+S
Sbjct: 45  KPFLISGGRDNNIIVWDL*PKKDGDEDQTWGVPRKTLTGHSHFISDLALSADSRFALSSS 224

Query: 113 DDQTIRVWNWQSRTCVCVLTGHNHYVMCAQFHPSEDLVVSASLDQTVRVWDISGLRKKNL 172
            D T+R+W+ +  +       H   V+   F P    + S   D+ +++W+I G  K  +
Sbjct: 225 WDATLRLWDIKKGSTTSRFINHTRDVLTVAFSPDNRQIASGGRDKNLKIWNIMGECKYTV 404

Query: 173 SPGAVESDVRGITGVDLFGTTDAVVKHVLEGHDRGVNWAAFHPTM--PLIVSGADDRQVK 230
              A                           H   V    FH     P++VS ++D+ +K
Sbjct: 405 DANA---------------------------HTDWVTCVRFHQDTKNPIVVSASNDKTIK 503

Query: 231 IW 232
           +W
Sbjct: 504 VW 509

 Score = 42.4 bits (98), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 31/125 (24%), Positives = 53/125 (42%), Gaps = 9/125 (7%)
 Frame = +3

Query: 216 TMPLIVSGADDRQVKIWRM------NESKAWEV--DTCRGHYNNVSCAVFHPRQELILSN 267
           T P ++SG  D  + +W +      +E + W V   T  GH + +S           LS+
Sbjct: 42  TKPFLISGGRDNNIIVWDL*PKKDGDEDQTWGVPRKTLTGHSHFISDLALSADSRFALSS 221

Query: 268 SEDKSIRVWDMSKRTGVQTFRRDHDRFWVLAAHP-NLNLFAAGHDGGMIVFKLERERPAY 326
           S D ++R+WD+ K +    F         +A  P N  + + G D  + ++ +  E   Y
Sbjct: 222 SWDATLRLWDIKKGSTTSRFINHTRDVLTVAFSPDNRQIASGGRDKNLKIWNIMGE-CKY 398

Query: 327 AVHGN 331
            V  N
Sbjct: 399 TVDAN 413
>13335
          Length = 863

 Score = 68.2 bits (165), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 63/233 (27%), Positives = 90/233 (38%), Gaps = 19/233 (8%)
 Frame = +1

Query: 96  IRTTFFHHEYPWILSASDDQTIRVWNWQSRTCVCVLTGHNHYVMCAQFHPSEDLVVSASL 155
           IR   F      ++S SDD TI +W   ++  V    GH   VM   + P+   +VS S 
Sbjct: 70  IRVCKFSPSSSHLVSGSDDDTICMWEVATQKLVRSYVGHEDSVMALAYSPNGHYLVSGSP 249

Query: 156 DQTVRVWDISGLRKKNLSPGAVESDVRGITGVDLFGTTDAVVKHVLEGHDRGVNWAAFHP 215
           +  + VWD S                        FG    +   V + HD GV    F P
Sbjct: 250 NGDLYVWDAS------------------------FGHCRHLTLRV-DAHDLGVTCCEFSP 354

Query: 216 TMP------------LIVSGADDRQVKIWRMN-ESKAWEV-----DTCRGHYNNVSCAVF 257
           T              L+ +G  D  +K+W  + +  + EV     D   GH + V    F
Sbjct: 355 TFGTACAENSSTCNLLLATGGKDNLIKLWTFSAQVGSPEVTLQCRDILSGHSDLVMACAF 534

Query: 258 HPRQELILSNSEDKSIRVWDMSKRTGVQTFRRDHDRFWVLAAHP-NLNLFAAG 309
            P   L+ S S DKS+R+WD  K   + +    H RF    A   +  L A+G
Sbjct: 535 SPSSALLASGSFDKSVRLWDSVKGVALFSIEACHSRFVTCCAFSIDGTLLASG 693

 Score = 67.0 bits (162), Expect = 5e-11,   Method: Compositional matrix adjust.
 Identities = 55/270 (20%), Positives = 110/270 (40%), Gaps = 17/270 (6%)
 Frame = +1

Query: 33  IQLWDYRMCTLIDKFDEHD-GPVRGIDFHKQQPLFVSGGDDYKIKVWNYKLRRCLFTLLG 91
           + +WD +  ++  ++       +R   F       VSG DD  I +W    ++ + + +G
Sbjct: 4   VIVWDVKTGSIKGEYQHASKSSIRVCKFSPSSSHLVSGSDDDTICMWEVATQKLVRSYVG 183

Query: 92  HLDYIRTTFFHHEYPWILSASDDQTIRVWNWQSRTC---VCVLTGHNHYVMCAQFHPS-- 146
           H D +    +     +++S S +  + VW+     C      +  H+  V C +F P+  
Sbjct: 184 HEDSVMALAYSPNGHYLVSGSPNGDLYVWDASFGHCRHLTLRVDAHDLGVTCCEFSPTFG 363

Query: 147 ----------EDLVVSASLDQTVRVWDISGLRKKNLSPGAVESDVRGITGVDLFGTTDAV 196
                       L+ +   D  +++W  S         G+ E  ++              
Sbjct: 364 TACAENSSTCNLLLATGGKDNLIKLWTFSA------QVGSPEVTLQ-------------- 483

Query: 197 VKHVLEGHDRGVNWAAFHPTMPLIVSGADDRQVKIWRMNESKA-WEVDTCRGHYNNVSCA 255
            + +L GH   V   AF P+  L+ SG+ D+ V++W   +  A + ++ C  H   V+C 
Sbjct: 484 CRDILSGHSDLVMACAFSPSSALLASGSFDKSVRLWDSVKGVALFSIEAC--HSRFVTCC 657

Query: 256 VFHPRQELILSNSEDKSIRVWDMSKRTGVQ 285
            F     L+ S S D+ I++W ++  + + 
Sbjct: 658 AFSIDGTLLASGSMDRIIKIWKLTDTSSIM 747

 Score = 65.1 bits (157), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 53/253 (20%), Positives = 96/253 (37%), Gaps = 23/253 (9%)
 Frame = +1

Query: 10  ARVKGLSFHPKRPWILTSLHNGVIQLWDYRMCTLIDKFDEHDGPVRGIDFHKQQPLFVSG 69
           + ++   F P    +++   +  I +W+     L+  +  H+  V  + +       VSG
Sbjct: 64  SSIRVCKFSPSSSHLVSGSDDDTICMWEVATQKLVRSYVGHEDSVMALAYSPNGHYLVSG 243

Query: 70  GDDYKIKVWNYKLRRCLFTLL---GHLDYIRTTFFHHEYP------------WILSASDD 114
             +  + VW+     C    L    H   +    F   +              + +   D
Sbjct: 244 SPNGDLYVWDASFGHCRHLTLRVDAHDLGVTCCEFSPTFGTACAENSSTCNLLLATGGKD 423

Query: 115 QTIRVWNWQSRT--------CVCVLTGHNHYVMCAQFHPSEDLVVSASLDQTVRVWDISG 166
             I++W + ++         C  +L+GH+  VM   F PS  L+ S S D++VR+WD   
Sbjct: 424 NLIKLWTFSAQVGSPEVTLQCRDILSGHSDLVMACAFSPSSALLASGSFDKSVRLWD--- 594

Query: 167 LRKKNLSPGAVESDVRGITGVDLFGTTDAVVKHVLEGHDRGVNWAAFHPTMPLIVSGADD 226
                            + GV LF         +   H R V   AF     L+ SG+ D
Sbjct: 595 ----------------SVKGVALFS--------IEACHSRFVTCCAFSIDGTLLASGSMD 702

Query: 227 RQVKIWRMNESKA 239
           R +KIW++ ++ +
Sbjct: 703 RIIKIWKLTDTSS 741
>17598
          Length = 875

 Score = 65.9 bits (159), Expect = 9e-11,   Method: Compositional matrix adjust.
 Identities = 43/157 (27%), Positives = 69/157 (43%), Gaps = 4/157 (2%)
 Frame = +1

Query: 12  VKGLSFHPKRPWILTSLHNGVIQLWDYRMCTLIDKFDEHDGPVRGIDFHKQQPLFVSGGD 71
           V  +S      ++L+S  +  ++LWD +      +F  H      + F        SGG 
Sbjct: 130 VSDVSLSADSRYVLSSSWDATLRLWDIKKGNTTRRFISHTRDALAVAFSPDNRQIASGGR 309

Query: 72  DYKIKVWNYKLRRCLFTLLG--HLDYIRTTFFHHE--YPWILSASDDQTIRVWNWQSRTC 127
           D  +K+WN  +  C FT+    H D++    FH +   P ++SAS D+TI+VW+ Q+ T 
Sbjct: 310 DKALKIWN-TVGECKFTVDANSHQDWVTCVKFHQDAKSPLVVSASMDKTIKVWDNQTMTL 486

Query: 128 VCVLTGHNHYVMCAQFHPSEDLVVSASLDQTVRVWDI 164
                GH   +           + S S D  V  W+I
Sbjct: 487 KHTFVGHKTQINAIDLALKTYYLASGSKDGIVMTWNI 597

 Score = 60.5 bits (145), Expect = 4e-09,   Method: Compositional matrix adjust.
 Identities = 49/160 (30%), Positives = 67/160 (41%), Gaps = 2/160 (1%)
 Frame = +1

Query: 130 VLTGHNHYVMCAQFHPSEDLVVSASLDQTVRVWDISGLRKKNLSPGAVESDVRGITGVDL 189
            L GH+H+V           V+S+S D T+R+WDI   +K N                  
Sbjct: 106 TLQGHSHFVSDVSLSADSRYVLSSSWDATLRLWDI---KKGN------------------ 222

Query: 190 FGTTDAVVKHVLEGHDRGVNWAAFHPTMPLIVSGADDRQVKIWRMNESKAWEVDTCRGHY 249
             TT   + H      R     AF P    I SG  D+ +KIW       + VD    H 
Sbjct: 223 --TTRRFISHT-----RDALAVAFSPDNRQIASGGRDKALKIWNTVGECKFTVD-ANSHQ 378

Query: 250 NNVSCAVFH--PRQELILSNSEDKSIRVWDMSKRTGVQTF 287
           + V+C  FH   +  L++S S DK+I+VWD    T   TF
Sbjct: 379 DWVTCVKFHQDAKSPLVVSASMDKTIKVWDNQTMTLKHTF 498

 Score = 50.4 bits (119), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 49/242 (20%), Positives = 83/242 (34%), Gaps = 3/242 (1%)
 Frame = +1

Query: 50  HDGPVRGIDFHKQQPLFVSGGDDYKIKVWNYKLRRCLFTLLGHLDYIRTTFFHHEYPWIL 109
           H   V  +         +S   D  +++W+ K        + H        F  +   I 
Sbjct: 118 HSHFVSDVSLSADSRYVLSSSWDATLRLWDIKKGNTTRRFISHTRDALAVAFSPDNRQIA 297

Query: 110 SASDDQTIRVWNWQSRTCVCV-LTGHNHYVMCAQFH--PSEDLVVSASLDQTVRVWDISG 166
           S   D+ +++WN        V    H  +V C +FH      LVVSAS+D+T++VWD   
Sbjct: 298 SGGRDKALKIWNTVGECKFTVDANSHQDWVTCVKFHQDAKSPLVVSASMDKTIKVWDNQT 477

Query: 167 LRKKNLSPGAVESDVRGITGVDLFGTTDAVVKHVLEGHDRGVNWAAFHPTMPLIVSGADD 226
           +                             +KH   GH   +N          + SG+ D
Sbjct: 478 M----------------------------TLKHTFVGHKTQINAIDLALKTYYLASGSKD 573

Query: 227 RQVKIWRMNESKAWEVDTCRGHYNNVSCAVFHPRQELILSNSEDKSIRVWDMSKRTGVQT 286
             V  W +          C    N V    F P +  +   + +  I++WD+  +  ++ 
Sbjct: 574 GIVMTWNIQNGTFLGKIDCDCEVNAVK---FSPNKYWLFVGTSE-GIQIWDLPNQKKIKD 741

Query: 287 FR 288
            R
Sbjct: 742 IR 747

 Score = 43.5 bits (101), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 41/176 (23%), Positives = 73/176 (41%), Gaps = 10/176 (5%)
 Frame = +1

Query: 4   KFETKSARVKGLSFHPKRPWILTSLHNGVIQLWD-YRMCTLIDKFDEHDGPVRGIDFHK- 61
           +F + +     ++F P    I +   +  +++W+    C      + H   V  + FH+ 
Sbjct: 232 RFISHTRDALAVAFSPDNRQIASGGRDKALKIWNTVGECKFTVDANSHQDWVTCVKFHQD 411

Query: 62  -QQPLFVSGGDDYKIKVWNYKLRRCLFTLLGHLDYIRTTFFHHEYPWILSASDDQTIRVW 120
            + PL VS   D  IKVW+ +      T +GH   I       +  ++ S S D  +  W
Sbjct: 412 AKSPLVVSASMDKTIKVWDNQTMTLKHTFVGHKTQINAIDLALKTYYLASGSKDGIVMTW 591

Query: 121 NWQSRT------CVCVLTGHNHYVMCAQFHPSED-LVVSASLDQTVRVWDISGLRK 169
           N Q+ T      C C        V   +F P++  L V  S  + +++WD+   +K
Sbjct: 592 NIQNGTFLGKIDCDC-------EVNAVKFSPNKYWLFVGTS--EGIQIWDLPNQKK 732

 Score = 33.1 bits (74), Expect = 0.63,   Method: Compositional matrix adjust.
 Identities = 24/108 (22%), Positives = 47/108 (43%), Gaps = 9/108 (8%)
 Frame = +1

Query: 219 LIVSGADDRQVKIWRM------NESKAW--EVDTCRGHYNNVSCAVFHPRQELILSNSED 270
            ++ G  D+ + +W +      +E + W     T +GH + VS          +LS+S D
Sbjct: 7   FLIXGGRDKLLIVWDLVPRKDGDEDETWGGPRRTLQGHSHFVSDVSLSADSRYVLSSSWD 186

Query: 271 KSIRVWDMSKRTGVQTF-RRDHDRFWVLAAHPNLNLFAAGHDGGMIVF 317
            ++R+WD+ K    + F     D   V  +  N  + + G D  + ++
Sbjct: 187 ATLRLWDIKKGNTTRRFISHTRDALAVAFSPDNRQIASGGRDKALKIW 330
>00561
          Length = 1003

 Score = 64.7 bits (156), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 42/138 (30%), Positives = 61/138 (44%), Gaps = 4/138 (2%)
 Frame = -3

Query: 32  VIQLWDYRMCTLIDKFDEHDGPVRGIDFHKQQPLFVSGGDDYKIKVWNYKLRRCLFTLL- 90
            ++LWD        +F+ H   V  + F       VSG  D  IK+WN  L  C FT+  
Sbjct: 797 TLRLWDLAAGKTTRRFEGHTKDVLSVAFSADNRQIVSGSRDKTIKLWN-TLAECKFTIQE 621

Query: 91  -GHLDYIRTTFF--HHEYPWILSASDDQTIRVWNWQSRTCVCVLTGHNHYVMCAQFHPSE 147
            GH D++    F  +H  P I+S   D+T++VWN  +        GHN Y+      P  
Sbjct: 620 DGHTDWVSCVRFSPNHSNPIIVSCGWDRTVKVWNLANCKLKNNHHGHNGYLNTVTVSPDG 441

Query: 148 DLVVSASLDQTVRVWDIS 165
            L  S   D    +WD++
Sbjct: 440 SLCTSGGKDSKALLWDLN 387

 Score = 60.1 bits (144), Expect = 6e-09,   Method: Compositional matrix adjust.
 Identities = 55/240 (22%), Positives = 91/240 (37%), Gaps = 4/240 (1%)
 Frame = -3

Query: 89  LLGHLDYIRTTFFHHEYPWILSASDDQTIRVWNWQSRTCVCVLTGHNHYVMCAQFHPSED 148
           L GH  +I       +  + LS S DQT+R+W+  +        GH   V+   F     
Sbjct: 878 LYGHSHFISDVVLSSDGNYALSGSWDQTLRLWDLAAGKTTRRFEGHTKDVLSVAFSADNR 699

Query: 149 LVVSASLDQTVRVWDISGLRKKNLSPGAVESDVRGITGVDLFGTTDAVVKHVLE--GHDR 206
            +VS S D+T+++W+                             T A  K  ++  GH  
Sbjct: 698 QIVSGSRDKTIKLWN-----------------------------TLAECKFTIQEDGHTD 606

Query: 207 GVNWAAFHP--TMPLIVSGADDRQVKIWRMNESKAWEVDTCRGHYNNVSCAVFHPRQELI 264
            V+   F P  + P+IVS   DR VK+W +   K    +   GH   ++     P   L 
Sbjct: 605 WVSCVRFSPNHSNPIIVSCGWDRTVKVWNLANCKL--KNNHHGHNGYLNTVTVSPDGSLC 432

Query: 265 LSNSEDKSIRVWDMSKRTGVQTFRRDHDRFWVLAAHPNLNLFAAGHDGGMIVFKLERERP 324
            S  +D    +WD++    + T   + D    L   PN       +   + ++ L  ++P
Sbjct: 431 TSGGKDSKALLWDLNDGKNLYTLEHN-DIINALCFSPNRYWLCVAYGPSIKIWDLACKKP 255

 Score = 45.8 bits (107), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 48/209 (22%), Positives = 90/209 (43%), Gaps = 25/209 (11%)
 Frame = -3

Query: 148 DLVVSASLDQTVRVWDISGLRKKNLSPGAVESDVRG----ITGV--------DLFGTTDA 195
           D ++SAS D+T+ VW ++  R ++ + G  +  + G    I+ V         L G+ D 
Sbjct: 971 DTIISASRDKTLIVWKLT--RDEDTNYGYPQKRLYGHSHFISDVVLSSDGNYALSGSWDQ 798

Query: 196 VVK----------HVLEGHDRGVNWAAFHPTMPLIVSGADDRQVKIWRMNESKAWEVDTC 245
            ++             EGH + V   AF      IVSG+ D+ +K+W       + +   
Sbjct: 797 TLRLWDLAAGKTTRRFEGHTKDVLSVAFSADNRQIVSGSRDKTIKLWNTLAECKFTIQE- 621

Query: 246 RGHYNNVSCAVFHPRQE--LILSNSEDKSIRVWDMSKRTGVQTFRRDHDRFWVLAAHPNL 303
            GH + VSC  F P     +I+S   D++++VW+++           +     +   P+ 
Sbjct: 620 DGHTDWVSCVRFSPNHSNPIIVSCGWDRTVKVWNLANCKLKNNHHGHNGYLNTVTVSPDG 441

Query: 304 NLF-AAGHDGGMIVFKLERERPAYAVHGN 331
           +L  + G D   +++ L   +  Y +  N
Sbjct: 440 SLCTSGGKDSKALLWDLNDGKNLYTLEHN 354

 Score = 37.4 bits (85), Expect = 0.033,   Method: Compositional matrix adjust.
 Identities = 28/112 (25%), Positives = 49/112 (43%), Gaps = 2/112 (1%)
 Frame = -3

Query: 12  VKGLSFHPKR--PWILTSLHNGVIQLWDYRMCTLIDKFDEHDGPVRGIDFHKQQPLFVSG 69
           V  + F P    P I++   +  +++W+   C L +    H+G +  +       L  SG
Sbjct: 602 VSCVRFSPNHSNPIIVSCGWDRTVKVWNLANCKLKNNHHGHNGYLNTVTVSPDGSLCTSG 423

Query: 70  GDDYKIKVWNYKLRRCLFTLLGHLDYIRTTFFHHEYPWILSASDDQTIRVWN 121
           G D K  +W+    + L+T L H D I    F     W+  A    +I++W+
Sbjct: 422 GKDSKALLWDLNDGKNLYT-LEHNDIINALCFSPNRYWLCVAY-GPSIKIWD 273
>12574
          Length = 521

 Score = 63.5 bits (153), Expect = 6e-10,   Method: Composition-based stats.
 Identities = 31/106 (29%), Positives = 52/106 (49%)
 Frame = +3

Query: 50  HDGPVRGIDFHKQQPLFVSGGDDYKIKVWNYKLRRCLFTLLGHLDYIRTTFFHHEYPWIL 109
           H   +  + F        S   D  IK+W     +   T+ GH   +    +  +   + 
Sbjct: 183 HTKALSAVKFSPNGDWLASSSADKLIKIWGAYDGKFEKTIAGHKLGLSDVAWSSDSKLLC 362

Query: 110 SASDDQTIRVWNWQSRTCVCVLTGHNHYVMCAQFHPSEDLVVSASL 155
           SASDD+T+++W + +  C+  L GH++YV C  F+P  +L+VS SL
Sbjct: 363 SASDDKTLKIWEFSTGKCMKTLKGHSNYVFCCNFNPQSNLIVSGSL 500

 Score = 61.6 bits (148), Expect = 2e-09,   Method: Composition-based stats.
 Identities = 36/138 (26%), Positives = 60/138 (43%)
 Frame = +3

Query: 131 LTGHNHYVMCAQFHPSEDLVVSASLDQTVRVWDISGLRKKNLSPGAVESDVRGITGVDLF 190
           L GH   +   +F P+ D + S+S D+ +++W                            
Sbjct: 174 LAGHTKALSAVKFSPNGDWLASSSADKLIKIW---------------------------- 269

Query: 191 GTTDAVVKHVLEGHDRGVNWAAFHPTMPLIVSGADDRQVKIWRMNESKAWEVDTCRGHYN 250
           G  D   +  + GH  G++  A+     L+ S +DD+ +KIW  +  K   + T +GH N
Sbjct: 270 GAYDGKFEKTIAGHKLGLSDVAWSSDSKLLCSASDDKTLKIWEFSTGKC--MKTLKGHSN 443

Query: 251 NVSCAVFHPRQELILSNS 268
            V C  F+P+  LI+S S
Sbjct: 444 YVFCCNFNPQSNLIVSGS 497

 Score = 50.4 bits (119), Expect = 5e-06,   Method: Composition-based stats.
 Identities = 28/113 (24%), Positives = 55/113 (48%)
 Frame = +3

Query: 197 VKHVLEGHDRGVNWAAFHPTMPLIVSGADDRQVKIWRMNESKAWEVDTCRGHYNNVSCAV 256
           +K  L GH + ++   F P    + S + D+ +KIW   + K  +  T  GH   +S   
Sbjct: 162 LKFTLAGHTKALSAVKFSPNGDWLASSSADKLIKIWGAYDGKFEK--TIAGHKLGLSDVA 335

Query: 257 FHPRQELILSNSEDKSIRVWDMSKRTGVQTFRRDHDRFWVLAAHPNLNLFAAG 309
           +    +L+ S S+DK++++W+ S    ++T +   +  +    +P  NL  +G
Sbjct: 336 WSSDSKLLCSASDDKTLKIWEFSTGKCMKTLKGHSNYVFCCNFNPQSNLIVSG 494

 Score = 44.3 bits (103), Expect = 3e-04,   Method: Composition-based stats.
 Identities = 35/138 (25%), Positives = 54/138 (39%)
 Frame = +3

Query: 87  FTLLGHLDYIRTTFFHHEYPWILSASDDQTIRVWNWQSRTCVCVLTGHNHYVMCAQFHPS 146
           FTL GH   +    F     W+ S+S D+ I++W          + GH   +    +   
Sbjct: 168 FTLAGHTKALSAVKFSPNGDWLASSSADKLIKIWGAYDGKFEKTIAGHKLGLSDVAWSSD 347

Query: 147 EDLVVSASLDQTVRVWDISGLRKKNLSPGAVESDVRGITGVDLFGTTDAVVKHVLEGHDR 206
             L+ SAS D+T+++W+ S                           T   +K  L+GH  
Sbjct: 348 SKLLCSASDDKTLKIWEFS---------------------------TGKCMK-TLKGHSN 443

Query: 207 GVNWAAFHPTMPLIVSGA 224
            V    F+P   LIVSG+
Sbjct: 444 YVFCCNFNPQSNLIVSGS 497
>26939
          Length = 388

 Score = 60.8 bits (146), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 25/57 (43%), Positives = 40/57 (70%)
 Frame = +2

Query: 107 WILSASDDQTIRVWNWQSRTCVCVLTGHNHYVMCAQFHPSEDLVVSASLDQTVRVWD 163
           +++SASDD+TIRVW+ +++ C+  L  H H+     FH +   V+S S+DQTV+VW+
Sbjct: 8   YLVSASDDKTIRVWDLRNKRCMKTLYAHQHFCTSIDFHKAHPYVISGSVDQTVKVWE 178

 Score = 54.3 bits (129), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 22/55 (40%), Positives = 35/55 (63%)
 Frame = +2

Query: 66  FVSGGDDYKIKVWNYKLRRCLFTLLGHLDYIRTTFFHHEYPWILSASDDQTIRVW 120
            VS  DD  I+VW+ + +RC+ TL  H  +  +  FH  +P+++S S DQT++VW
Sbjct: 11  LVSASDDKTIRVWDLRNKRCMKTLYAHQHFCTSIDFHKAHPYVISGSVDQTVKVW 175

 Score = 37.7 bits (86), Expect = 0.027,   Method: Compositional matrix adjust.
 Identities = 17/56 (30%), Positives = 28/56 (50%)
 Frame = +2

Query: 23 WILTSLHNGVIQLWDYRMCTLIDKFDEHDGPVRGIDFHKQQPLFVSGGDDYKIKVW 78
          +++++  +  I++WD R    +     H      IDFHK  P  +SG  D  +KVW
Sbjct: 8  YLVSASDDKTIRVWDLRNKRCMKTLYAHQHFCTSIDFHKAHPYVISGSVDQTVKVW 175

 Score = 35.4 bits (80), Expect = 0.14,   Method: Compositional matrix adjust.
 Identities = 14/58 (24%), Positives = 32/58 (55%)
 Frame = +2

Query: 220 IVSGADDRQVKIWRMNESKAWEVDTCRGHYNNVSCAVFHPRQELILSNSEDKSIRVWD 277
           +VS +DD+ +++W +   +   + T   H +  +   FH     ++S S D++++VW+
Sbjct: 11  LVSASDDKTIRVWDLRNKRC--MKTLYAHQHFCTSIDFHKAHPYVISGSVDQTVKVWE 178
>37180
          Length = 681

 Score = 60.5 bits (145), Expect = 4e-09,   Method: Composition-based stats.
 Identities = 33/93 (35%), Positives = 56/93 (60%), Gaps = 1/93 (1%)
 Frame = +1

Query: 199 HVLEGHDRGVNWAAFHPTMPLIVSGADDRQVKIWRMNESKAWEVDTCRGHYNNVSCAVFH 258
           +VL GHD+ ++    HPT  L+V+ + D   ++W   +S A  V+  +GH   V+ AVF 
Sbjct: 1   NVLNGHDQELSDVHAHPTQRLVVTSSKDMTFRLWDFRDS-ALLVNVFQGHTQPVTSAVF- 174

Query: 259 PRQELILSNSEDKSIRVWDM-SKRTGVQTFRRD 290
              + ++S S+D+++RVWDM + R+ + T R D
Sbjct: 175 ASGDKVVSGSDDRTVRVWDMRNMRSPIATIRTD 273

 Score = 50.4 bits (119), Expect = 4e-06,   Method: Composition-based stats.
 Identities = 31/110 (28%), Positives = 50/110 (45%)
 Frame = +1

Query: 130 VLTGHNHYVMCAQFHPSEDLVVSASLDQTVRVWDISGLRKKNLSPGAVESDVRGITGVDL 189
           VL GH+  +     HP++ LVV++S D T R+WD                          
Sbjct: 4   VLNGHDQELSDVHAHPTQRLVVTSSKDMTFRLWDFR------------------------ 111

Query: 190 FGTTDAVVKHVLEGHDRGVNWAAFHPTMPLIVSGADDRQVKIWRMNESKA 239
                A++ +V +GH + V  A F  +   +VSG+DDR V++W M   ++
Sbjct: 112 ---DSALLVNVFQGHTQPVTSAVF-ASGDKVVSGSDDRTVRVWDMRNMRS 249

 Score = 40.8 bits (94), Expect = 0.004,   Method: Composition-based stats.
 Identities = 22/68 (32%), Positives = 35/68 (51%), Gaps = 1/68 (1%)
 Frame = +1

Query: 18  HPKRPWILTSLHNGVIQLWDYR-MCTLIDKFDEHDGPVRGIDFHKQQPLFVSGGDDYKIK 76
           HP +  ++TS  +   +LWD+R    L++ F  H  PV    F     + VSG DD  ++
Sbjct: 46  HPTQRLVVTSSKDMTFRLWDFRDSALLVNVFQGHTQPVTSAVFASGDKV-VSGSDDRTVR 222

Query: 77  VWNYKLRR 84
           VW+ +  R
Sbjct: 223 VWDMRNMR 246

 Score = 38.5 bits (88), Expect = 0.015,   Method: Composition-based stats.
 Identities = 20/76 (26%), Positives = 38/76 (50%), Gaps = 1/76 (1%)
 Frame = +1

Query: 50  HDGPVRGIDFHKQQPLFVSGGDDYKIKVWNYKLRRCLFTLL-GHLDYIRTTFFHHEYPWI 108
           HD  +  +  H  Q L V+   D   ++W+++    L  +  GH   + +  F      +
Sbjct: 16  HDQELSDVHAHPTQRLVVTSSKDMTFRLWDFRDSALLVNVFQGHTQPVTSAVFASGDK-V 192

Query: 109 LSASDDQTIRVWNWQS 124
           +S SDD+T+RVW+ ++
Sbjct: 193 VSGSDDRTVRVWDMRN 240
>01327
          Length = 2215

 Score = 58.9 bits (141), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 47/224 (20%), Positives = 92/224 (41%), Gaps = 22/224 (9%)
 Frame = +3

Query: 33  IQLWDYRMCTLIDKFDEHDGPVRGIDFHKQQPLFVSGGDDYKIKVWNYKLRRCLFTLLGH 92
           + L+DY+   L D++  HD  +  + +        S   D  IK+W       +   +GH
Sbjct: 111 VVLYDYQNGRLEDRWTGHDREITKVCYGASCNGMFSASRDKTIKMWQRGNSHSIRDFIGH 290

Query: 93  LDYIRTTFFHHEYPWILSASDDQTIRVWNWQSRTCVCVLTGHNHYVMCAQFHPSEDLVVS 152
              +     + +   + S S D T+R+W+ ++  C+       + V   ++ P   L++ 
Sbjct: 291 DMVVTAIHLNTDNTLLCSGSRDNTVRIWDVETGACLRQNNIPQNLVTDVKWLPGSHLIIQ 470

Query: 153 ASLDQTVRVWD------ISGLRKKNLSPGAVESDVRG---ITGVDLFGT----------T 193
           A  D+ VR++D      +    KK     + +    G   +T  + FG           +
Sbjct: 471 AGEDKEVRIYDSRTLGIVRSFTKKQYIQMSCDVTADGQFCLTCSNGFGGNGCEATLWQLS 650

Query: 194 DAVVKHVLEGHDRGVNWAAFHPT---MPLIVSGADDRQVKIWRM 234
           D  +++  +GH   +    F P+   M LI + + D  V++W M
Sbjct: 651 DGSIQNEFKGHREAIEACLFLPSNQDMTLIATASRDCSVRVWNM 782

 Score = 58.2 bits (139), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 57/242 (23%), Positives = 104/242 (42%), Gaps = 25/242 (10%)
 Frame = +3

Query: 62  QQPLFVSGGDDYKIKVWNYKLRRCLFTLLGHLDYIRTTFFHHEYPWILSASDDQTIRVWN 121
           Q  L +SG  D  + +++Y+  R      GH   I    +      + SAS D+TI++W 
Sbjct: 72  QPGLCLSGSKDKSVVLYDYQNGRLEDRWTGHDREITKVCYGASCNGMFSASRDKTIKMWQ 251

Query: 122 WQSRTCVCVLTGHNHYVMCAQFHPSEDLVVSASLDQTVRVWDI---SGLRKKNLSPGAVE 178
             +   +    GH+  V     +    L+ S S D TVR+WD+   + LR+ N+ P  + 
Sbjct: 252 RGNSHSIRDFIGHDMVVTAIHLNTDNTLLCSGSRDNTVRIWDVETGACLRQNNI-PQNLV 428

Query: 179 SDVRGITGVDLF--GTTDAVVKHVLEGHDRGVNWAAFHPTMPLIVS-------------- 222
           +DV+ + G  L      D  V+ + +    G+   +F     + +S              
Sbjct: 429 TDVKWLPGSHLIIQAGEDKEVR-IYDSRTLGIV-RSFTKKQYIQMSCDVTADGQFCLTCS 602

Query: 223 ---GADDRQVKIWRMNESKAWEVDTCRGHYNNVSCAVFHPRQE---LILSNSEDKSIRVW 276
              G +  +  +W++++      +  +GH   +   +F P  +   LI + S D S+RVW
Sbjct: 603 NGFGGNGCEATLWQLSDGSI--QNEFKGHREAIEACLFLPSNQDMTLIATASRDCSVRVW 776

Query: 277 DM 278
           +M
Sbjct: 777 NM 782

 Score = 32.7 bits (73), Expect = 0.89,   Method: Compositional matrix adjust.
 Identities = 18/64 (28%), Positives = 29/64 (45%), Gaps = 3/64 (4%)
 Frame = +3

Query: 69  GGDDYKIKVWNYKLRRCLFTLLGHLDYIRTTFF---HHEYPWILSASDDQTIRVWNWQSR 125
           GG+  +  +W            GH + I    F   + +   I +AS D ++RVWN  ++
Sbjct: 612 GGNGCEATLWQLSDGSIQNEFKGHREAIEACLFLPSNQDMTLIATASRDCSVRVWNMFTK 791

Query: 126 TCVC 129
            CVC
Sbjct: 792 ECVC 803
>17602
          Length = 481

 Score = 56.6 bits (135), Expect = 5e-08,   Method: Compositional matrix adjust.
 Identities = 36/136 (26%), Positives = 65/136 (47%), Gaps = 5/136 (3%)
 Frame = +3

Query: 34  QLWDYRMCTLIDKFDEHDGPVRGIDFHKQQPLFVSGGDDYKIKVWNYKLRRCLFTLLGHL 93
           ++WD +    +     H  PV  + F++   L VS   D   ++W+    +CL TL+   
Sbjct: 3   RIWDVKTGKCLKTLPAHSDPVTAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLXTLIDD- 179

Query: 94  DYIRTTF--FHHEYPWILSASDDQTIRVWNWQSRTCVCVLTGHNH--YVMCAQFHPSED- 148
           D    +F  F     +IL+A+ D T+++W++    C+    GH +  Y + A F  +   
Sbjct: 180 DNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYVGHRNEKYCIFANFSVTGGK 359

Query: 149 LVVSASLDQTVRVWDI 164
            +VS S D  V +W++
Sbjct: 360 WIVSGSEDNMVYIWNL 407

 Score = 55.1 bits (131), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 29/91 (31%), Positives = 50/91 (54%), Gaps = 1/91 (1%)
 Frame = +3

Query: 76  KVWNYKLRRCLFTLLGHLDYIRTTFFHHEYPWILSASDDQTIRVWNWQSRTCVCVLT-GH 134
           ++W+ K  +CL TL  H D +    F+ +   I+S+S D   R+W+  S  C+  L    
Sbjct: 3   RIWDVKTGKCLKTLPAHSDPVTAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLXTLIDDD 182

Query: 135 NHYVMCAQFHPSEDLVVSASLDQTVRVWDIS 165
           N  V   +F P+   +++A+LD T+++WD S
Sbjct: 183 NPPVSFVKFSPNGKYILAATLDNTLKLWDYS 275

 Score = 50.4 bits (119), Expect(2) = 4e-07,   Method: Compositional matrix adjust.
 Identities = 33/127 (25%), Positives = 59/127 (46%), Gaps = 7/127 (5%)
 Frame = +3

Query: 2   LTKFETKSARVKGLSFHPKRPWILTSLHNGVIQLWDYR----MCTLIDKFDEHDGPVRGI 57
           L      S  V  + F+     I++S ++G+ ++WD      + TLI   D+ + PV  +
Sbjct: 33  LKTLPAHSDPVTAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLXTLI---DDDNPPVSFV 203

Query: 58  DFHKQQPLFVSGGDDYKIKVWNYKLRRCLFTLLGHLDYIRTTFFHHEYP---WILSASDD 114
            F       ++   D  +K+W+Y   +CL T +GH +     F +       WI+S S+D
Sbjct: 204 KFSPNGKYILAATLDNTLKLWDYSKGKCLKTYVGHRNEKYCIFANFSVTGGKWIVSGSED 383

Query: 115 QTIRVWN 121
             + +WN
Sbjct: 384 NMVYIWN 404

 Score = 22.7 bits (47), Expect(2) = 4e-07,   Method: Composition-based stats.
 Identities = 9/23 (39%), Positives = 12/23 (52%)
 Frame = +1

Query: 124 SRTCVCVLTGHNHYVMCAQFHPS 146
           ++  V  L GH   V+C   HPS
Sbjct: 412 TKEIVQKLQGHTDVVLCCACHPS 480

 Score = 45.8 bits (107), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 34/164 (20%), Positives = 67/164 (40%), Gaps = 3/164 (1%)
 Frame = +3

Query: 118 RVWNWQSRTCVCVLTGHNHYVMCAQFHPSEDLVVSASLDQTVRVWDISGLRKKNLSPGAV 177
           R+W+ ++  C+  L  H+  V    F+    L+VS+S D   R+WD +            
Sbjct: 3   RIWDVKTGKCLKTLPAHSDPVTAVHFNRDGSLIVSSSYDGLCRIWDTA------------ 146

Query: 178 ESDVRGITGVDLFGTTDAVVKHVLEGHDRGVNWAAFHPTMPLIVSGADDRQVKIWRMNES 237
                          +   +  +++  +  V++  F P    I++   D  +K+W  ++ 
Sbjct: 147 ---------------SGQCLXTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKG 281

Query: 238 KAWEVDTCRGHYNNVSCAVFH---PRQELILSNSEDKSIRVWDM 278
           K   + T  GH N   C   +      + I+S SED  + +W++
Sbjct: 282 KC--LKTYVGHRNEKYCIFANFSVTGGKWIVSGSEDNMVYIWNL 407
>21105
          Length = 650

 Score = 55.5 bits (132), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 28/107 (26%), Positives = 53/107 (49%), Gaps = 4/107 (3%)
 Frame = +1

Query: 60  HKQQPLFVSGGDDYKIKVWNYKLRRCLFTLLGHLDYIRTTFFHHEYPWILSASDDQTIRV 119
           H   P+ ++  +D  I+ ++    + +  ++ HLD + +        ++LS S D +IR+
Sbjct: 91  HPTMPITITAHEDRHIRFFDNNTGKLIHAMVAHLDSVTSLAVDPNGLYLLSGSHDCSIRL 270

Query: 120 WNWQSRTCVCVLTGH----NHYVMCAQFHPSEDLVVSASLDQTVRVW 162
           WN  S+TCV  +T H    +  +    FHP +  + SA  D   +V+
Sbjct: 271 WNLDSKTCVQEITSHRKKFDESIHDVAFHPQKPYIASAGADALAKVF 411

 Score = 51.2 bits (121), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 33/109 (30%), Positives = 51/109 (46%), Gaps = 5/109 (4%)
 Frame = +1

Query: 214 HPTMPLIVSGADDRQVKIWRMNESKAWEVDTCRGHYNNVSCAVFHPRQELILSNSEDKSI 273
           HPTMP+ ++  +DR ++ +  N  K   +     H ++V+     P    +LS S D SI
Sbjct: 91  HPTMPITITAHEDRHIRFFDNNTGKL--IHAMVAHLDSVTSLAVDPNGLYLLSGSHDCSI 264

Query: 274 RVWDMSKRTGVQTFRRDHDRF----WVLAAHPNLNLFA-AGHDGGMIVF 317
           R+W++  +T VQ       +F      +A HP     A AG D    VF
Sbjct: 265 RLWNLDSKTCVQEITSHRKKFDESIHDVAFHPQKPYIASAGADALAKVF 411

 Score = 37.0 bits (84), Expect = 0.047,   Method: Compositional matrix adjust.
 Identities = 20/71 (28%), Positives = 33/71 (46%), Gaps = 4/71 (5%)
 Frame = +1

Query: 12  VKGLSFHPKRPWILTSLHNGVIQLWDYRMCTLIDKFDEH----DGPVRGIDFHKQQPLFV 67
           V  L+  P   ++L+  H+  I+LW+    T + +   H    D  +  + FH Q+P   
Sbjct: 199 VTSLAVDPNGLYLLSGSHDCSIRLWNLDSKTCVQEITSHRKKFDESIHDVAFHPQKPYIA 378

Query: 68  SGGDDYKIKVW 78
           S G D   KV+
Sbjct: 379 SAGADALAKVF 411
>03156
          Length = 1014

 Score = 55.5 bits (132), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 45/218 (20%), Positives = 88/218 (40%), Gaps = 22/218 (10%)
 Frame = +1

Query: 39  RMCTLIDKFDEHDGPVRGIDFHKQQPLFVSGGDDYKIKVWNYKLRRCLFTLLGHLDYIRT 98
           +M  L D++  HD  +  + +        S   D  IK+W       +   +GH   +  
Sbjct: 19  KMGRLEDRWTGHDREITKVCYGASCNGMFSASRDKTIKMWQRGNSHSIRDFIGHDMVVTA 198

Query: 99  TFFHHEYPWILSASDDQTIRVWNWQSRTCVCVLTGHNHYVMCAQFHPSEDLVVSASLDQT 158
              + +   + S S D T+R+W+ ++  C+       + V   ++ P   L++ A  D+ 
Sbjct: 199 IHLNTDNTLLCSGSRDNTVRIWDVETGACLRQNNIPQNLVTDVKWLPGSHLIIQAGEDKE 378

Query: 159 VRVWD------ISGLRKKNLSPGAVESDVRG---ITGVDLFGT----------TDAVVKH 199
           VR++D      +    KK     + +    G   +T  + FG           +D  +++
Sbjct: 379 VRIYDSRTLGIVRSFTKKQYIQMSCDVTADGQFCLTCSNGFGGNGCEATLWQLSDGSIQN 558

Query: 200 VLEGHDRGVNWAAFHPT---MPLIVSGADDRQVKIWRM 234
             +GH   +    F P+   M LI + + D  V++W M
Sbjct: 559 EFKGHREAIEACLFLPSNQDMTLIATASRDCSVRVWNM 672

 Score = 37.4 bits (85), Expect = 0.036,   Method: Compositional matrix adjust.
 Identities = 19/76 (25%), Positives = 37/76 (48%)
 Frame = +1

Query: 203 GHDRGVNWAAFHPTMPLIVSGADDRQVKIWRMNESKAWEVDTCRGHYNNVSCAVFHPRQE 262
           GHDR +    +  +   + S + D+ +K+W+   S +  +    GH   V+    +    
Sbjct: 49  GHDREITKVCYGASCNGMFSASRDKTIKMWQRGNSHS--IRDFIGHDMVVTAIHLNTDNT 222

Query: 263 LILSNSEDKSIRVWDM 278
           L+ S S D ++R+WD+
Sbjct: 223 LLCSGSRDNTVRIWDV 270

 Score = 33.1 bits (74), Expect = 0.76,   Method: Compositional matrix adjust.
 Identities = 18/64 (28%), Positives = 29/64 (45%), Gaps = 3/64 (4%)
 Frame = +1

Query: 69  GGDDYKIKVWNYKLRRCLFTLLGHLDYIRTTFF---HHEYPWILSASDDQTIRVWNWQSR 125
           GG+  +  +W            GH + I    F   + +   I +AS D ++RVWN  ++
Sbjct: 502 GGNGCEATLWQLSDGSIQNEFKGHREAIEACLFLPSNQDMTLIATASRDCSVRVWNMFTK 681

Query: 126 TCVC 129
            CVC
Sbjct: 682 ECVC 693
>03387
          Length = 1891

 Score = 55.1 bits (131), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 56/227 (24%), Positives = 89/227 (39%), Gaps = 10/227 (4%)
 Frame = +1

Query: 108 ILSASDDQTIRVWNWQSRT-------CVCVLTGHNHYVMCAQFH-PSEDLVVSASLDQTV 159
           +LSASDD TI +W+  S            + TGH   V    +H   E L  S + DQ +
Sbjct: 409 LLSASDDHTICLWDINSTQRESRVVDAHTIFTGHTSVVEDVAWHLLHESLFGSVADDQKL 588

Query: 160 RVWDISGLRKKNLSPGAVESDVRGITGVDLFGTTDAVVKHVLEGHDRGVNWAAFHPTMPL 219
            +WD                             T +   HV++ H   VN  +F+P    
Sbjct: 589 MIWDTR-------------------------SNTTSKPSHVVDAHTAEVNCLSFNPYSEF 693

Query: 220 IV-SGADDRQVKIWRMNESKAWEVDTCRGHYNNVSCAVFHPRQELILSNS-EDKSIRVWD 277
           I+ +G+ D+ V +W +   K  ++ +   H + +    + P  E IL++S  D+ + VWD
Sbjct: 694 ILATGSADKTVALWDLRNLKL-KLHSFESHKDEIFQVQWSPHNETILASSGTDRRLHVWD 870

Query: 278 MSKRTGVQTFRRDHDRFWVLAAHPNLNLFAAGHDGGMIVFKLERERP 324
           +SK  G +    D +        P L     GH   +  F      P
Sbjct: 871 LSK-IGEEQLPEDAED-----GPPELLFIHGGHTAKISDFSWNPNEP 993

 Score = 49.3 bits (116), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 55/246 (22%), Positives = 100/246 (40%), Gaps = 30/246 (12%)
 Frame = +1

Query: 66  FVSGGDDYKIKVWNYKLRR---------CLFTLLGHLDYIRTTFFHHEYPWIL-SASDDQ 115
            +S  DD+ I +W+    +          +FT  GH   +    +H  +  +  S +DDQ
Sbjct: 409 LLSASDDHTICLWDINSTQRESRVVDAHTIFT--GHTSVVEDVAWHLLHESLFGSVADDQ 582

Query: 116 TIRVWNWQSRTCV---CVLTGHNHYVMCAQFHP-SEDLVVSASLDQTVRVWDISGLRKKN 171
            + +W+ +S T      V+  H   V C  F+P SE ++ + S D+TV +WD+  L+ K 
Sbjct: 583 KLMIWDTRSNTTSKPSHVVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLK- 759

Query: 172 LSPGAVESDVRGITGVDLFGTTDAVVKHVLEGHDR---GVNWAAFHPTMPLIVSGADDRQ 228
                                      H  E H      V W+  + T  ++ S   DR+
Sbjct: 760 --------------------------LHSFESHKDEIFQVQWSPHNET--ILASSGTDRR 855

Query: 229 VKIWRMNESKAWEVDTCR------------GHYNNVSCAVFHPRQELIL-SNSEDKSIRV 275
           + +W +++    ++                GH   +S   ++P +  I+ S SED  ++V
Sbjct: 856 LHVWDLSKIGEEQLPEDAEDGPPELLFIHGGHTAKISDFSWNPNEPWIVCSVSEDNIMQV 1035

Query: 276 WDMSKR 281
           W M++ 
Sbjct: 1036WQMAEN 1053
>27806
          Length = 419

 Score = 54.3 bits (129), Expect = 3e-07,   Method: Composition-based stats.
 Identities = 24/58 (41%), Positives = 35/58 (60%)
 Frame = -1

Query: 105 YPWILSASDDQTIRVWNWQSRTCVCVLTGHNHYVMCAQFHPSEDLVVSASLDQTVRVW 162
           +P I +AS D T R+++ ++  CV    GH   V   +FHP +DLV++AS D T  VW
Sbjct: 389 HPIIGTASADHTARIYSIETGACVLTYGGHQGSVNAVRFHPGQDLVLTASGDHTAHVW 216

 Score = 39.3 bits (90), Expect = 0.010,   Method: Composition-based stats.
 Identities = 20/62 (32%), Positives = 32/62 (51%)
 Frame = -1

Query: 215 PTMPLIVSGADDRQVKIWRMNESKAWEVDTCRGHYNNVSCAVFHPRQELILSNSEDKSIR 274
           P  P+I + + D   +I+ +       V T  GH  +V+   FHP Q+L+L+ S D +  
Sbjct: 395 PGHPIIGTASADHTARIYSIETGAC--VLTYGGHQGSVNAVRFHPGQDLVLTASGDHTAH 222

Query: 275 VW 276
           VW
Sbjct: 221 VW 216

 Score = 31.6 bits (70), Expect = 1.9,   Method: Composition-based stats.
 Identities = 12/36 (33%), Positives = 18/36 (50%)
 Frame = -1

Query: 203 GHDRGVNWAAFHPTMPLIVSGADDRQVKIWRMNESK 238
           GH   VN   FHP   L+++ + D    +WR   S+
Sbjct: 305 GHQGSVNAVRFHPGQDLVLTASGDHTAHVWRAQFSQ 198
>15118
          Length = 1074

 Score = 50.4 bits (119), Expect = 5e-06,   Method: Composition-based stats.
 Identities = 37/139 (26%), Positives = 62/139 (44%), Gaps = 3/139 (2%)
 Frame = +3

Query: 50  HDGPVRGIDFHKQQPLFVSGGDDYKIKVWNYKLR---RCLFTLLGHLDYIRTTFFHHEYP 106
           H   VRG+ F     L ++ G D  IK W +  R   R L   L   + I     H +  
Sbjct: 189 HVSGVRGVAFDAFNCLLITAGGDCDIKFWRFGSRDRARVLLKELKMSEGISRILLHRDSN 368

Query: 107 WILSASDDQTIRVWNWQSRTCVCVLTGHNHYVMCAQFHPSEDLVVSASLDQTVRVWDISG 166
            +    +D T+ V +  +   V V +GH++ +    F      +++AS+D TVR W +  
Sbjct: 369 MLAVVLEDFTVSVIDVDTLRVVRVFSGHSNSITDLSFSGDGRWLITASMDCTVRTWSL-- 542

Query: 167 LRKKNLSPGAVESDVRGIT 185
           +  + +   AVE+ V  +T
Sbjct: 543 VHGRLIDCFAVEAAVTSLT 599
>19498
          Length = 903

 Score = 49.3 bits (116), Expect = 8e-06,   Method: Compositional matrix adjust.
 Identities = 39/143 (27%), Positives = 59/143 (41%), Gaps = 18/143 (12%)
 Frame = -1

Query: 46  KFDEHDGPVRGIDFHKQQPLFVSGGDDYKIKVWN-----------------YKLRRCLFT 88
           + D H G V  + + +      SGGDD  I +W                   +  R + T
Sbjct: 801 QMDSHLGCVNCVRWSENGKFLASGGDDKLIMIWQISRGFGSGKSFGSNVTILEHWRSVAT 622

Query: 89  LLGHLDYIRTTFFHHEYPWILSASDDQTIRVWN-WQSRTCVCVLTGHNHYVMCAQFHPSE 147
           L GH   +    +  +  W+ S S D TI VWN  +    V V+ GH   V    + P  
Sbjct: 621 LRGHAGDVLDLAWSPQDLWLASCSVDNTIVVWNALKFSEQVAVIRGHAGMVKGVTWDPVG 442

Query: 148 DLVVSASLDQTVRVWDISGLRKK 170
             + S S D+T+RVW  S  +++
Sbjct: 441 RYLASQSDDKTLRVWRTSDWKEE 373

 Score = 45.1 bits (105), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 41/173 (23%), Positives = 67/173 (38%), Gaps = 5/173 (2%)
 Frame = -1

Query: 112 SDDQTIRVWNWQSRTCVCVLTGHNHYVMCAQFHPSEDLVVSASLDQTVRVWDISGLRKKN 171
           +DD   RV        +C +  H   V C ++  +   + S   D+ + +W IS      
Sbjct: 831 ADDDVPRV--------LCQMDSHLGCVNCVRWSENGKFLASGGDDKLIMIWQIS------ 694

Query: 172 LSPGAVESDVRGITGVDLFGTTDAVVKH-----VLEGHDRGVNWAAFHPTMPLIVSGADD 226
                     RG      FG+   +++H      L GH   V   A+ P    + S + D
Sbjct: 693 ----------RGFGSGKSFGSNVTILEHWRSVATLRGHAGDVLDLAWSPQDLWLASCSVD 544

Query: 227 RQVKIWRMNESKAWEVDTCRGHYNNVSCAVFHPRQELILSNSEDKSIRVWDMS 279
             + +W   +    +V   RGH   V    + P    + S S+DK++RVW  S
Sbjct: 543 NTIVVWNALKFSE-QVAVIRGHAGMVKGVTWDPVGRYLASQSDDKTLRVWRTS 388

 Score = 39.7 bits (91), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 44/208 (21%), Positives = 77/208 (37%), Gaps = 32/208 (15%)
 Frame = -1

Query: 70  GDDYKIKVWNYK------------LRRCLFTLLGHLDYIRTTFFHHEYPWILSASDDQTI 117
           GD  K+ +WN              + R L  +  HL  +    +     ++ S  DD+ I
Sbjct: 891 GDSGKVVIWNMAPIRDEKEEADDDVPRVLCQMDSHLGCVNCVRWSENGKFLASGGDDKLI 712

Query: 118 RVW--------------------NWQSRTCVCVLTGHNHYVMCAQFHPSEDLVVSASLDQ 157
            +W                    +W+S   V  L GH   V+   + P +  + S S+D 
Sbjct: 711 MIWQISRGFGSGKSFGSNVTILEHWRS---VATLRGHAGDVLDLAWSPQDLWLASCSVDN 541

Query: 158 TVRVWDISGLRKKNLSPGAVESDVRGITGVDLFGTTDAVVKHVLEGHDRGVNWAAFHPTM 217
           T+ VW+   L+                     F    AV++    GH   V    + P  
Sbjct: 540 TIVVWN--ALK---------------------FSEQVAVIR----GHAGMVKGVTWDPVG 442

Query: 218 PLIVSGADDRQVKIWRMNESKAWEVDTC 245
             + S +DD+ +++WR ++   W+ +TC
Sbjct: 441 RYLASQSDDKTLRVWRTSD---WKEETC 367

 Score = 32.0 bits (71), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 26/106 (24%), Positives = 43/106 (40%), Gaps = 15/106 (14%)
 Frame = -1

Query: 201 LEGHDRGVNWAAFHPTMPLIVSGADDRQVKIWRMNES--------------KAW-EVDTC 245
           ++ H   VN   +      + SG DD+ + IW+++                + W  V T 
Sbjct: 798 MDSHLGCVNCVRWSENGKFLASGGDDKLIMIWQISRGFGSGKSFGSNVTILEHWRSVATL 619

Query: 246 RGHYNNVSCAVFHPRQELILSNSEDKSIRVWDMSKRTGVQTFRRDH 291
           RGH  +V    + P+   + S S D +I VW+  K +      R H
Sbjct: 618 RGHAGDVLDLAWSPQDLWLASCSVDNTIVVWNALKFSEQVAVIRGH 481
>12960
          Length = 550

 Score = 48.5 bits (114), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 32/121 (26%), Positives = 54/121 (44%)
 Frame = +2

Query: 54  VRGIDFHKQQPLFVSGGDDYKIKVWNYKLRRCLFTLLGHLDYIRTTFFHHEYPWILSASD 113
           VR + F       ++ G D  +K+WN      L T +GH   +       +   I S   
Sbjct: 182 VRAVRFSVDSRYCMTCGSDKSVKLWNPHRELFLKTYIGHGHEVLDAQGSGDNSQICSGGI 361

Query: 114 DQTIRVWNWQSRTCVCVLTGHNHYVMCAQFHPSEDLVVSASLDQTVRVWDISGLRKKNLS 173
           D+T+ +++  S   +     H   V C +F+    +++S SLD TVR WD    R ++ +
Sbjct: 362 DKTVVLFDVASGQALRKYRDHAGTVNCVKFNEESTVILSGSLDNTVRAWDT---RSRSHT 532

Query: 174 P 174
           P
Sbjct: 533 P 535

 Score = 38.1 bits (87), Expect = 0.024,   Method: Compositional matrix adjust.
 Identities = 26/119 (21%), Positives = 47/119 (39%)
 Frame = +2

Query: 8   KSARVKGLSFHPKRPWILTSLHNGVIQLWDYRMCTLIDKFDEHDGPVRGIDFHKQQPLFV 67
           K   V+ + F     + +T   +  ++LW+      +  +  H   V             
Sbjct: 170 KQQAVRAVRFSVDSRYCMTCGSDKSVKLWNPHRELFLKTYIGHGHEVLDAQGSGDNSQIC 349

Query: 68  SGGDDYKIKVWNYKLRRCLFTLLGHLDYIRTTFFHHEYPWILSASDDQTIRVWNWQSRT 126
           SGG D  + +++    + L     H   +    F+ E   ILS S D T+R W+ +SR+
Sbjct: 350 SGGIDKTVVLFDVASGQALRKYRDHAGTVNCVKFNEESTVILSGSLDNTVRAWDTRSRS 526

 Score = 37.7 bits (86), Expect = 0.028,   Method: Compositional matrix adjust.
 Identities = 21/85 (24%), Positives = 40/85 (47%), Gaps = 3/85 (3%)
 Frame = +2

Query: 96  IRTTFFHHEYPWILSASDDQTIRVWNWQSRTCVCVLTGHNHYVMCAQFHPSEDLVVSASL 155
           +R   F  +  + ++   D+++++WN      +    GH H V+ AQ       + S  +
Sbjct: 182 VRAVRFSVDSRYCMTCGSDKSVKLWNPHRELFLKTYIGHGHEVLDAQGSGDNSQICSGGI 361

Query: 156 DQTVRVWDIS---GLRKKNLSPGAV 177
           D+TV ++D++    LRK     G V
Sbjct: 362 DKTVVLFDVASGQALRKYRDHAGTV 436

 Score = 36.6 bits (83), Expect = 0.059,   Method: Compositional matrix adjust.
 Identities = 20/63 (31%), Positives = 32/63 (50%)
 Frame = +2

Query: 220 IVSGADDRQVKIWRMNESKAWEVDTCRGHYNNVSCAVFHPRQELILSNSEDKSIRVWDMS 279
           I SG  D+ V ++ +   +A  +   R H   V+C  F+    +ILS S D ++R WD  
Sbjct: 344 ICSGGIDKTVVLFDVASGQA--LRKYRDHAGTVNCVKFNEESTVILSGSLDNTVRAWDTR 517

Query: 280 KRT 282
            R+
Sbjct: 518 SRS 526
>14555
          Length = 627

 Score = 38.1 bits (87), Expect(2) = 2e-05,   Method: Composition-based stats.
 Identities = 21/63 (33%), Positives = 31/63 (49%)
 Frame = -2

Query: 127 CVCVLTGHNHYVMCAQFHPSEDLVVSASLDQTVRVWDISGLRKKNLSPGAVESDVRGITG 186
           CV +  GH   + C +F+PS D   + S D T R++D+   R+ N      ES + G   
Sbjct: 623 CVQMFEGHEADINCVRFYPSGDAFATGSDDATCRLFDLRADREVNCYRK--ESIIFGCNA 450

Query: 187 VDL 189
           VD 
Sbjct: 449 VDF 441

 Score = 29.3 bits (64), Expect(2) = 2e-05,   Method: Composition-based stats.
 Identities = 16/59 (27%), Positives = 25/59 (42%)
 Frame = -3

Query: 225 DDRQVKIWRMNESKAWEVDTCRGHYNNVSCAVFHPRQELILSNSEDKSIRVWDMSKRTG 283
           +D  V +W  +  K        GH N VSC    P    + + S D ++R+W   +  G
Sbjct: 406 NDYTVNVW--DALKGMRSTILYGHDNRVSCLRISPDGTSLCTGSWDYTLRIWA*ERERG 236

 Score = 37.7 bits (86), Expect = 0.027,   Method: Composition-based stats.
 Identities = 16/54 (29%), Positives = 28/54 (51%)
 Frame = -3

Query: 109 LSASDDQTIRVWNWQSRTCVCVLTGHNHYVMCAQFHPSEDLVVSASLDQTVRVW 162
           L  ++D T+ VW+        +L GH++ V C +  P    + + S D T+R+W
Sbjct: 418 LGVTNDYTVNVWDALKGMRSTILYGHDNRVSCLRISPDGTSLCTGSWDYTLRIW 257

 Score = 32.3 bits (72), Expect = 1.1,   Method: Composition-based stats.
 Identities = 12/49 (24%), Positives = 26/49 (53%)
 Frame = -2

Query: 242 VDTCRGHYNNVSCAVFHPRQELILSNSEDKSIRVWDMSKRTGVQTFRRD 290
           V    GH  +++C  F+P  +   + S+D + R++D+     V  +R++
Sbjct: 620 VQMFEGHEADINCVRFYPSGDAFATGSDDATCRLFDLRADREVNCYRKE 474
>20662
          Length = 1220

 Score = 46.6 bits (109), Expect = 6e-05,   Method: Compositional matrix adjust.
 Identities = 40/158 (25%), Positives = 70/158 (44%), Gaps = 8/158 (5%)
 Frame = +2

Query: 24  ILTSLHNGVIQLWDY----RMCTLIDKFDEHDGPVRGIDFHKQQPLFVSGGDDYKIKVWN 79
           +L  L  G + LW+     +M +++    EHD     +  +     ++S   D+ IKVWN
Sbjct: 293 VLVGLDTGGVALWELQDEDKMFSMLSSACEHDDMTASVSINSDXSHYLSASYDHGIKVWN 472

Query: 80  YKLRRCLFTLLGHLDYIRTTFFHHEYPWI-LSASDDQTIRVWNW-QSRTCVCVLTGHNHY 137
             L   L+T   H D +     H   P + LS S D  I +W+  +S+   C+    + +
Sbjct: 473 TDLTS-LYTYRAHSDIVWDVQCHPTEPALFLSCSQDGKIVLWDVRESKPATCLPKCSSGF 649

Query: 138 -VMCAQFHP-SEDLVVSASLDQTVRVWDISGLRKKNLS 173
              C Q+ P + ++         V V D+  + +KN+S
Sbjct: 650 KPTCVQWQPNARNMYAVGDEGGHVSVQDLRMVVEKNVS 763
>19863
          Length = 502

 Score = 46.6 bits (109), Expect = 7e-05,   Method: Composition-based stats.
 Identities = 21/69 (30%), Positives = 34/69 (49%)
 Frame = +1

Query: 66  FVSGGDDYKIKVWNYKLRRCLFTLLGHLDYIRTTFFHHEYPWILSASDDQTIRVWNWQSR 125
            VSG  D  I VW+ +       L GH  ++    F  +  W+LS S+D T+R+WN +  
Sbjct: 16  LVSGSSDMSIVVWDVENGVQKLRLQGHAGWVNDVHFSQDQCWLLSCSNDNTVRIWNIEES 195

Query: 126 TCVCVLTGH 134
             + ++  H
Sbjct: 196 DQIPIVMEH 222

 Score = 37.4 bits (85), Expect = 0.036,   Method: Composition-based stats.
 Identities = 19/57 (33%), Positives = 31/57 (54%)
 Frame = +1

Query: 108 ILSASDDQTIRVWNWQSRTCVCVLTGHNHYVMCAQFHPSEDLVVSASLDQTVRVWDI 164
           ++S S D +I VW+ ++      L GH  +V    F   +  ++S S D TVR+W+I
Sbjct: 16  LVSGSSDMSIVVWDVENGVQKLRLQGHAGWVNDVHFSQDQCWLLSCSNDNTVRIWNI 186

 Score = 30.0 bits (66), Expect = 6.8,   Method: Composition-based stats.
 Identities = 18/63 (28%), Positives = 31/63 (49%), Gaps = 2/63 (3%)
 Frame = +1

Query: 220 IVSGADDRQVKIWRMNESKAWEVDTCR--GHYNNVSCAVFHPRQELILSNSEDKSIRVWD 277
           +VSG+ D  + +W +       V   R  GH   V+   F   Q  +LS S D ++R+W+
Sbjct: 16  LVSGSSDMSIVVWDVENG----VQKLRLQGHAGWVNDVHFSQDQCWLLSCSNDNTVRIWN 183

Query: 278 MSK 280
           + +
Sbjct: 184 IEE 192
>18981
          Length = 407

 Score = 45.4 bits (106), Expect = 1e-04,   Method: Composition-based stats.
 Identities = 42/157 (26%), Positives = 63/157 (40%)
 Frame = -2

Query: 108 ILSASDDQTIRVWNWQSRTCVCVLTGHNHYVMCAQFHPSEDLVVSASLDQTVRVWDISGL 167
           I+SA+ D+T+RVW  ++   +  L GHN  V C   +     VVS S D+T+ VW++   
Sbjct: 379 IISAATDRTLRVWCLKNTCLLHTLRGHNDDVECVCIYGRR--VVSGSWDKTLIVWEVDTG 206

Query: 168 RKKNLSPGAVESDVRGITGVDLFGTTDAVVKHVLEGHDRGVNWAAFHPTMPLIVSGADDR 227
           R                              H L GH   +    F       VSG+ D 
Sbjct: 205 RP----------------------------VHQLHGHTEAITAVQFDEGKA--VSGSADG 116

Query: 228 QVKIWRMNESKAWEVDTCRGHYNNVSCAVFHPRQELI 264
            V+ W ++  +     T  G    V C V++  QE+I
Sbjct: 115 DVRTWALDTGQCLLTMTT-GQDIEVYCVVYN--QEVI 14

 Score = 45.1 bits (105), Expect = 2e-04,   Method: Composition-based stats.
 Identities = 32/103 (31%), Positives = 44/103 (42%)
 Frame = -2

Query: 60  HKQQPLFVSGGDDYKIKVWNYKLRRCLFTLLGHLDYIRTTFFHHEYPWILSASDDQTIRV 119
           H    + +S   D  ++VW  K    L TL GH D +     +     ++S S D+T+ V
Sbjct: 397 HLLDNMIISAATDRTLRVWCLKNTCLLHTLRGHNDDVECVCIYGRR--VVSGSWDKTLIV 224

Query: 120 WNWQSRTCVCVLTGHNHYVMCAQFHPSEDLVVSASLDQTVRVW 162
           W   +   V  L GH   +   QF   E   VS S D  VR W
Sbjct: 223 WEVDTGRPVHQLHGHTEAITAVQF--DEGKAVSGSADGDVRTW 101

 Score = 40.8 bits (94), Expect = 0.003,   Method: Composition-based stats.
 Identities = 19/60 (31%), Positives = 37/60 (61%)
 Frame = -2

Query: 219 LIVSGADDRQVKIWRMNESKAWEVDTCRGHYNNVSCAVFHPRQELILSNSEDKSIRVWDM 278
           +I+S A DR +++W +  +    + T RGH ++V C   + R+  ++S S DK++ VW++
Sbjct: 382 MIISAATDRTLRVWCLKNTCL--LHTLRGHNDDVECVCIYGRR--VVSGSWDKTLIVWEV 215
>01462
          Length = 995

 Score = 43.5 bits (101), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 21/59 (35%), Positives = 34/59 (57%)
 Frame = +2

Query: 68  SGGDDYKIKVWNYKLRRCLFTLLGHLDYIRTTFFHHEYPWILSASDDQTIRVWNWQSRT 126
           +G  D KI VW+ +  + L  + GH DYI      ++    +SAS+D T+R+W+ +S T
Sbjct: 248 AGAGDRKIHVWDIEAGQYLNAMEGHKDYIHKVVMKNDAQECVSASEDGTVRMWDIRSST 424

 Score = 34.3 bits (77), Expect = 0.32,   Method: Compositional matrix adjust.
 Identities = 18/57 (31%), Positives = 29/57 (50%)
 Frame = +2

Query: 108 ILSASDDQTIRVWNWQSRTCVCVLTGHNHYVMCAQFHPSEDLVVSASLDQTVRVWDI 164
           + + + D+ I VW+ ++   +  + GH  Y+            VSAS D TVR+WDI
Sbjct: 242 LYAGAGDRKIHVWDIEAGQYLNAMEGHKDYIHKVVMKNDAQECVSASEDGTVRMWDI 412

 Score = 34.3 bits (77), Expect = 0.34,   Method: Compositional matrix adjust.
 Identities = 16/63 (25%), Positives = 33/63 (52%)
 Frame = +2

Query: 220 IVSGADDRQVKIWRMNESKAWEVDTCRGHYNNVSCAVFHPRQELILSNSEDKSIRVWDMS 279
           + +GA DR++ +W +   +   ++   GH + +   V     +  +S SED ++R+WD+ 
Sbjct: 242 LYAGAGDRKIHVWDIEAGQ--YLNAMEGHKDYIHKVVMKNDAQECVSASEDGTVRMWDIR 415

Query: 280 KRT 282
             T
Sbjct: 416 SST 424
>02960
          Length = 1577

 Score = 42.4 bits (98), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 68/308 (22%), Positives = 119/308 (38%), Gaps = 56/308 (18%)
 Frame = +2

Query: 67  VSGGDDYKIKVWNYKLRRCLFTLLGHLDYIRTTFF--HHEYPWI---LSASDDQTIRVWN 121
           +SG  D  +++W+ K    + T+ GH   ++   +  H E   +   ++ S DQT  VW 
Sbjct: 527 LSGSYDNTVRLWSTK-GEAIMTIPGHTSPVKCVAWIKHDESSGVSTFVTGSHDQTALVWQ 703

Query: 122 WQSRT----CVCVLTGHNHYVMCAQFHPSEDLVVSASLDQTVRVW----DISGLRKKN-- 171
           WQ  T    C     GH   V C    P    + + S D+ +++W    ++ G + ++  
Sbjct: 704 WQRETNEVDCRLSCRGHAASVDCVAVSPDSQQMCTGSWDKMLKLWSTDCNVDGDQSEDTE 883

Query: 172 -------------------LSPGAVESDVRGITGVDLFGTTDAVVKHVLEGHD------- 205
                              L+       V  +  +D      +   H L   D       
Sbjct: 884 RPSKKKKSAKSTTQTRVPVLTLSGHAEAVSAVRWLDPHRVVTSSWDHSLRLWDLHTAQQT 1063

Query: 206 ------RGVNWAAFHPTMPLIVSGADDRQVKIWRMNESKAWEVDTCR----GHYNNVSCA 255
                 + V   A+ P   ++++G+ DR V   R+ + +  E +T +     H   V+  
Sbjct: 1064SLIQGSKAVLDVAYSPLSHMLITGSADRHV---RLVDPRCSEGETVKCAFTSHTGWVTGV 1234

Query: 256 VFHP-RQELILSNSEDKSIRVWDM-SKRTGVQTFRRDHDRFWVLAAH---PNLNLFAAGH 310
            + P R+ L LS S D  +++WD  S +  +       DR  +LA     P L L + G 
Sbjct: 1235DWSPTREHLFLSGSYDNVLKLWDTRSPKATLYDMNWHEDR--ILAVDWSIPEL-LLSGGV 1405

Query: 311 DGGMIVFK 318
           D  + VF 
Sbjct: 1406DNKLHVFS 1429
>21763
          Length = 923

 Score = 42.4 bits (98), Expect = 0.001,   Method: Composition-based stats.
 Identities = 40/167 (23%), Positives = 65/167 (38%), Gaps = 23/167 (13%)
 Frame = +1

Query: 3   TKFETKSARVKGLSFHPKRPWILTSLHNGVIQLWDYRMCTLIDKFDEHDGPVRGIDFHKQ 62
           + F      ++ + FHP RP    +     +++++      + K   +   +  +D H  
Sbjct: 301 SPFSQSKGLIQCVKFHPLRPIFFVASQR-FVRIYNLLTQQFVKKLQTNCKWISSMDVH-- 471

Query: 63  QPLFVSGGDDYKIKVWNYKLRRCLF----------TLLGHLDYIRTTFFHHEYPWILSAS 112
                 GGD+  + + +Y  + C F           L  H   +R   +HH YP   SAS
Sbjct: 472 -----PGGDN--VIIGSYDCKSCWFDLDLSTKPYKILRHHKRAVRHVSYHHRYPLFASAS 630

Query: 113 DDQTIRVWNWQ---------SRTCVCVLTGHNHY----VMCAQFHPS 146
           DD +I V + +             V VL GH       VM  QFHP+
Sbjct: 631 DDGSIIVCHGKVFGDLLLNPQIVPVKVLRGHKITNKLGVMDCQFHPT 771
>19140
          Length = 573

 Score = 42.4 bits (98), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 22/67 (32%), Positives = 35/67 (52%), Gaps = 1/67 (1%)
 Frame = -3

Query: 246 RGHYNNVSCAVFHPRQELILSNSEDKSIRVWDMSKRTGVQTFRRDHDRFWVLAAHPNL-N 304
           +GH +NV   V +      LS S D +IR+W + ++  V TFR   +  W L A+ +   
Sbjct: 496 KGHTDNVKALVLNRDGTQCLSGSSDGTIRLWSLGQQRCVATFRVHDEGVWALQANESFTT 317

Query: 305 LFAAGHD 311
           L++ G D
Sbjct: 316 LYSGGRD 296

 Score = 40.0 bits (92), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 25/87 (28%), Positives = 36/87 (41%)
 Frame = -3

Query: 86  LFTLLGHLDYIRTTFFHHEYPWILSASDDQTIRVWNWQSRTCVCVLTGHNHYVMCAQFHP 145
           L  L GH D ++    + +    LS S D TIR+W+   + CV     H+  V   Q + 
Sbjct: 508 LMKLKGHTDNVKALVLNRDGTQCLSGSSDGTIRLWSLGQQRCVATFRVHDEGVWALQANE 329

Query: 146 SEDLVVSASLDQTVRVWDISGLRKKNL 172
           S   + S   D  V   DI     + L
Sbjct: 328 SFTTLYSGGRDHQVWATDIKNPDNREL 248

 Score = 29.6 bits (65), Expect = 7.1,   Method: Compositional matrix adjust.
 Identities = 19/78 (24%), Positives = 32/78 (41%)
 Frame = -3

Query: 39  RMCTLIDKFDEHDGPVRGIDFHKQQPLFVSGGDDYKIKVWNYKLRRCLFTLLGHLDYIRT 98
           R C  + K   H   V+ +  ++     +SG  D  I++W+   +RC+ T          
Sbjct: 523 RTCHKLMKLKGHTDNVKALVLNRDGTQCLSGSSDGTIRLWSLGQQRCVATF--------- 371

Query: 99  TFFHHEYPWILSASDDQT 116
              H E  W L A++  T
Sbjct: 370 -RVHDEGVWALQANESFT 320
>03395
          Length = 2795

 Score = 42.0 bits (97), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 27/109 (24%), Positives = 47/109 (43%), Gaps = 1/109 (0%)
 Frame = +2

Query: 13  KGLSFHPKRPWILTSLHNGVIQLWDYRMCTLIDKFD-EHDGPVRGIDFHKQQPLFVSGGD 71
           K + F  K   ILTS  +  I  W+     L+ + +    G +  ID  +     ++GG+
Sbjct: 281 KCVCFGGKDLHILTSGTDHKIGYWEVGDGGLLRELEGSQTGAINTIDIDRDGQTILTGGE 460

Query: 72  DYKIKVWNYKLRRCLFTLLGHLDYIRTTFFHHEYPWILSASDDQTIRVW 120
           D  +K+W Y       T +GH + I          +I+S  +D  + +W
Sbjct: 461 DSLLKLWRYNEGEVTHTGIGHSNQITKARICPNRHYIVSGGEDGALHIW 607

 Score = 35.8 bits (81), Expect = 0.12,   Method: Compositional matrix adjust.
 Identities = 23/105 (21%), Positives = 42/105 (40%), Gaps = 1/105 (0%)
 Frame = +2

Query: 59  FHKQQPLFVSGGDDYKIKVWNYKLRRCLFTLLG-HLDYIRTTFFHHEYPWILSASDDQTI 117
           F  +    ++ G D+KI  W       L  L G     I T     +   IL+  +D  +
Sbjct: 293 FGGKDLHILTSGTDHKIGYWEVGDGGLLRELEGSQTGAINTIDIDRDGQTILTGGEDSLL 472

Query: 118 RVWNWQSRTCVCVLTGHNHYVMCAQFHPSEDLVVSASLDQTVRVW 162
           ++W +          GH++ +  A+  P+   +VS   D  + +W
Sbjct: 473 KLWRYNEGEVTHTGIGHSNQITKARICPNRHYIVSGGEDGALHIW 607

 Score = 35.0 bits (79), Expect = 0.18,   Method: Compositional matrix adjust.
 Identities = 43/192 (22%), Positives = 77/192 (40%), Gaps = 23/192 (11%)
 Frame = +2

Query: 66  FVSGGDDYKIKVWNY-------KLRRCLFT-LLGHLDYIRTTFFHHEYPWILSASDDQTI 117
            VSGG + +++VW+        K R  L   +  H   +     H      +SAS D + 
Sbjct: 41  LVSGGGEGQVRVWDIVKDMLTGKTRGDLVANMKEHKGKVTAIQIHTNDRCCVSASTDGST 220

Query: 118 RVWNWQSRTCVCVLTGHNHYVMCAQFHPSEDLVVSASLDQTVRVWDIS--GLRKK--NLS 173
            +W+  + T   ++   N    C  F   +  ++++  D  +  W++   GL ++     
Sbjct: 221 IIWDLITNTRSQIVLA-NTLFKCVCFGGKDLHILTSGTDHKIGYWEVGDGGLLRELEGSQ 397

Query: 174 PGAVES-DVRGITGVDLFGTTDAVVK----------HVLEGHDRGVNWAAFHPTMPLIVS 222
            GA+ + D+       L G  D+++K          H   GH   +  A   P    IVS
Sbjct: 398 TGAINTIDIDRDGQTILTGGEDSLLKLWRYNEGEVTHTGIGHSNQITKARICPNRHYIVS 577

Query: 223 GADDRQVKIWRM 234
           G +D  + IW+ 
Sbjct: 578 GGEDGALHIWKF 613
>01768
          Length = 1424

 Score = 41.6 bits (96), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 27/110 (24%), Positives = 51/110 (46%), Gaps = 7/110 (6%)
 Frame = +3

Query: 1    MLTKFETKSARVKGLSFHPKRPWILTSL-HNGVIQLWDYRM-----CTLIDKFDEHDGPV 54
            +LT  E  S  +  ++++P    +L S   +G+I++WD RM      +    F  H  PV
Sbjct: 954  VLTVPEAHSRDINVINWNPIEKHLLASGGDDGIIKIWDLRMFRNKPVSAQASFKLHSQPV 1133

Query: 55   RGIDFHKQ-QPLFVSGGDDYKIKVWNYKLRRCLFTLLGHLDYIRTTFFHH 103
              ++++ Q   +  + G+D +I +W++ + R        LD      F H
Sbjct: 1134 TSLEWNPQDSSVLAASGEDDQITIWDFSVERDEGEGEEELDVPAQLLFQH 1283
>13278
          Length = 870

 Score = 41.6 bits (96), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 23/80 (28%), Positives = 36/80 (45%)
 Frame = +1

Query: 108 ILSASDDQTIRVWNWQSRTCVCVLTGHNHYVMCAQFHPSEDLVVSASLDQTVRVWDISGL 167
           + SAS D T+R+W  +   C+  LT H   V    F P    + S S D+ V +W     
Sbjct: 121 LASASFDSTVRLWEVERGLCLHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIW----- 285

Query: 168 RKKNLSPGAVESDVRGITGV 187
              N+  G++    +G  G+
Sbjct: 286 ---NVQTGSLVHSYKGTGGI 336

 Score = 35.4 bits (80), Expect = 0.14,   Method: Compositional matrix adjust.
 Identities = 25/100 (25%), Positives = 45/100 (45%)
 Frame = +1

Query: 65  LFVSGGDDYKIKVWNYKLRRCLFTLLGHLDYIRTTFFHHEYPWILSASDDQTIRVWNWQS 124
           +  S   D  +++W  +   CL TL  H + + +  F  +  ++ S S D+ + +WN Q+
Sbjct: 118 ILASASFDSTVRLWEVERGLCLHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNVQT 297

Query: 125 RTCVCVLTGHNHYVMCAQFHPSEDLVVSASLDQTVRVWDI 164
            + V    G          H  + +  SAS D +V V D+
Sbjct: 298 GSLVHSYKGTGGIFEVCWNHRGDKVGASAS-DGSVFVLDL 414
>00825
          Length = 1821

 Score = 41.2 bits (95), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 63/278 (22%), Positives = 114/278 (41%), Gaps = 31/278 (11%)
 Frame = -2

Query: 30   NGVIQLWDYRMCTLIDKFDEHDGPVRGIDFHKQQPLFVSGGDDYKIKVW----------- 78
            +G +  W+     +  +   HDG V G+  H     F S G D  IK W           
Sbjct: 1808 DGELICWNLPKQQMACRVQAHDGIVHGMAAHSSGQYFFSCGSDKTIKQWSLDPEGTIAPE 1629

Query: 79   --NYKLRRCLFTLLGHLDYIRTTFFHHEYPWILSASDDQTIRVWNWQSRTCVCVLTGHNH 136
              N  L +C++T L H  + +   F      + S S    + VW+ +    +   +    
Sbjct: 1628 PVNTLLAKCIYTSLDH--HWKDDIF------VTSGS---RVDVWDEKRSEPMRSFSWGVE 1482

Query: 137  YVMCAQFHPSED-LVVSASLDQTVRVWDISG----------LRKKNLSPGAVESDVRGIT 185
             V   +F+P E  L+ +A+ D+++ ++D+ G          +R   LS   +E+    IT
Sbjct: 1481 SVHHVKFNPVETYLLGAAAHDRSILLYDMRGSAPLRKVVMKMRTNALSWNPMEAFT--IT 1308

Query: 186  GVDLFG---TTD----AVVKHVLEGHDRGVNWAAFHPTMPLIVSGADDRQVKIWRMNESK 238
              +  G   T D    ++  ++   H   V    + PT    VS   D+ ++I+ +++  
Sbjct: 1307 SANEDGNLYTFDMRKLSMPLNMHRDHTAAVMDVDYCPTGREFVSAGYDKVIRIFPVDKGH 1128

Query: 239  AWEVDTCRGHYNNVSCAVFHPRQELILSNSEDKSIRVW 276
            + EV   +     V   V+    + I S S++ +IRVW
Sbjct: 1127 SREVYHTK-RMQRVGSVVWSRDSKYIFSASDEMNIRVW 1017
>01805
          Length = 2124

 Score = 40.8 bits (94), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 35/148 (23%), Positives = 62/148 (41%), Gaps = 17/148 (11%)
 Frame = -1

Query: 108 ILSASDDQTIRVWNWQSRTCVCVLTGHNHYVMCAQFHPSED-LVVSASLDQTVRVWDISG 166
           + SAS D T+ +W+          T H+  V C  +HP E+  +++ S D TV+V D   
Sbjct: 528 LASASADTTVALWDLSEGKMAMNFTQHSREVQCCNWHPQEEQTLLTGSFDNTVKVVDCRS 349

Query: 167 LRKKNLS---PGAVESDV-RGITGVDLFGTTDAVVKHVLE-----------GHDRGVNWA 211
               + S    G VE  V      + L   TD  + +  +            H   V   
Sbjct: 348 AETCHKSWTVEGEVEKAVWNHHNPLQLLACTDKGMVYCFDIRHEKPVFSVGAHSSCVTGV 169

Query: 212 AFHPTMP-LIVSGADDRQVKIWRMNESK 238
                +P L+++ ++D+ +K+W + + K
Sbjct: 168 CLSSQIPGLMITTSEDKTMKVWDIQDDK 85

 Score = 38.5 bits (88), Expect = 0.016,   Method: Compositional matrix adjust.
 Identities = 29/113 (25%), Positives = 54/113 (47%), Gaps = 3/113 (2%)
 Frame = -1

Query: 219 LIVSGADDRQVKIWRMNESKAWEVDTCRGHYNNVSCAVFHPRQE-LILSNSEDKSIRVWD 277
           ++ S + D  V +W ++E K         H   V C  +HP++E  +L+ S D +++V D
Sbjct: 531 VLASASADTTVALWDLSEGKM--AMNFTQHSREVQCCNWHPQEEQTLLTGSFDNTVKVVD 358

Query: 278 M-SKRTGVQTFRRDHDRFWVLAAHPN-LNLFAAGHDGGMIVFKLERERPAYAV 328
             S  T  +++  + +    +  H N L L A    G +  F +  E+P ++V
Sbjct: 357 CRSAETCHKSWTVEGEVEKAVWNHHNPLQLLACTDKGMVYCFDIRHEKPVFSV 199
>15780
          Length = 735

 Score = 40.4 bits (93), Expect = 0.004,   Method: Composition-based stats.
 Identities = 18/59 (30%), Positives = 31/59 (52%)
 Frame = -1

Query: 107 WILSASDDQTIRVWNWQSRTCVCVLTGHNHYVMCAQFHPSEDLVVSASLDQTVRVWDIS 165
           ++ +A  D T+ VW+  S T V  LT H   V    F     ++ S  +D ++R+WD++
Sbjct: 732 YLSTAGADHTVIVWDIASGTAVAHLTAHTDTVYALCFSRDGTVLASGGMDNSIRLWDLA 556
>21960
          Length = 756

 Score = 39.7 bits (91), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 20/71 (28%), Positives = 34/71 (47%), Gaps = 1/71 (1%)
 Frame = +1

Query: 97  RTTFFHHEYPWILSASDDQTIRVWNWQSRTCVCVLTGHNHYVM-CAQFHPSEDLVVSASL 155
           R  FF      I+S SDD  I  W+  +      + G +  V+ C + HP+  ++ ++ L
Sbjct: 376 RVNFFGPHSEHIISGSDDGNIFYWDKNTEAVTNFMKGDDAGVVNCLEQHPTMPVLATSGL 555

Query: 156 DQTVRVWDISG 166
           D  V++W  S 
Sbjct: 556 DHNVKIWTPSA 588

 Score = 33.5 bits (75), Expect = 0.56,   Method: Compositional matrix adjust.
 Identities = 29/101 (28%), Positives = 40/101 (39%), Gaps = 1/101 (0%)
 Frame = +1

Query: 143 FHPSEDLVVSASLDQTVRVWDISGLRKKNLSPGAVESDVRGITGVDLFGTTDAVVKHVLE 202
           F P  + ++S S D  +  WD      KN                     T+AV    ++
Sbjct: 388 FGPHSEHIISGSDDGNIFYWD------KN---------------------TEAVTN-FMK 483

Query: 203 GHDRGV-NWAAFHPTMPLIVSGADDRQVKIWRMNESKAWEV 242
           G D GV N    HPTMP++ +   D  VKIW  +     EV
Sbjct: 484 GDDAGVVNCLEQHPTMPVLATSGLDHNVKIWTPSAKPETEV 606

 Score = 30.0 bits (66), Expect = 6.4,   Method: Compositional matrix adjust.
 Identities = 43/200 (21%), Positives = 82/200 (41%), Gaps = 31/200 (15%)
 Frame = +1

Query: 113 DDQTIRVWNWQSRTCVCVL---TGHNHYV--MCAQFHP-SEDLVVSASLDQTVRVWDISG 166
           +D T++ ++ +S  C  +L   T  N  V       HP + +  +S S D  +RV+D   
Sbjct: 1   EDSTVKHFDLRSNCCTTMLRCYTKENRRVRLFSIAHHPFASEFCISGS-DDKLRVYDKRK 177

Query: 167 LRK--KNLSP-----GAVESDVRGITGVDLFGT-TDAVVKHVLEGHDRGVNWAA------ 212
           L K    +SP       +   V   +G ++  + +DA +  + +   +G   +A      
Sbjct: 178 LDKTVHEMSPKDTKVSQITCAVYNHSGSEILASYSDAAIYLL*QPQLQGRRISALLRRPH 357

Query: 213 ----------FHPTMPLIVSGADDRQVKIWRMNESKAWEVDTCRGHYNNV-SCAVFHPRQ 261
                     F P    I+SG+DD  +  W  N       +  +G    V +C   HP  
Sbjct: 358 K*PYHQRVNFFGPHSEHIISGSDDGNIFYWDKNTEAV--TNFMKGDDAGVVNCLEQHPTM 531

Query: 262 ELILSNSEDKSIRVWDMSKR 281
            ++ ++  D ++++W  S +
Sbjct: 532 PVLATSGLDHNVKIWTPSAK 591
>16199
          Length = 694

 Score = 38.5 bits (88), Expect = 0.016,   Method: Composition-based stats.
 Identities = 13/37 (35%), Positives = 23/37 (62%)
 Frame = +2

Query: 252 VSCAVFHPRQELILSNSEDKSIRVWDMSKRTGVQTFR 288
           ++CA FHP   +  + +ED  I++WD+ +R  V  F+
Sbjct: 80  LTCAQFHPDGLIFATGTEDSVIKIWDLKERANVANFQ 190

 Score = 35.8 bits (81), Expect = 0.10,   Method: Composition-based stats.
 Identities = 31/134 (23%), Positives = 45/134 (33%), Gaps = 17/134 (12%)
 Frame = +2

Query: 17  FHPKRPWILTSLHNGVIQLWDYRMCTLIDKFDEHDGPVRGIDF--------HKQQPLFVS 68
           FHP      T   + VI++WD +    +  F  H GPV  I F         +Q+ L+ +
Sbjct: 95  FHPDGLIFATGTEDSVIKIWDLKERANVANFQGHQGPVTSISFSETDTTWPRQQKTLWSN 274

Query: 69  GGD-----DYKIKVWNYKLR--RCLFTLLGHLDYIRTTFFHHEYPWILSASDDQTIRVWN 121
            G        K+  W   +R  RC  T                          +    W 
Sbjct: 275 CGT*GN*RTSKLYSWETSMR*KRCALT--------------------------RVEPTWQ 376

Query: 122 WQSRT--CVCVLTG 133
           WQ++T  C C   G
Sbjct: 377 WQAQTSECTCASNG 418

 Score = 31.6 bits (70), Expect = 2.1,   Method: Composition-based stats.
 Identities = 9/27 (33%), Positives = 17/27 (62%)
 Frame = +2

Query: 138 VMCAQFHPSEDLVVSASLDQTVRVWDI 164
           + CAQFHP   +  + + D  +++WD+
Sbjct: 80  LTCAQFHPDGLIFATGTEDSVIKIWDL 160

 Score = 30.8 bits (68), Expect = 3.1,   Method: Composition-based stats.
 Identities = 23/84 (27%), Positives = 33/84 (39%), Gaps = 13/84 (15%)
 Frame = +2

Query: 211 AAFHPTMPLIVSGADDRQVKIWRMNESKAWEVDTCRGHYNNVSCAVFH------PRQELI 264
           A FHP   +  +G +D  +KIW + E     V   +GH   V+   F       PRQ+  
Sbjct: 89  AQFHPDGLIFATGTEDSVIKIWDLKERA--NVANFQGHQGPVTSISFSETDTTWPRQQKT 262

Query: 265 L-------SNSEDKSIRVWDMSKR 281
           L        N     +  W+ S R
Sbjct: 263 LWSNCGT*GN*RTSKLYSWETSMR 334
>17266
          Length = 480

 Score = 38.1 bits (87), Expect = 0.019,   Method: Composition-based stats.
 Identities = 30/134 (22%), Positives = 54/134 (40%), Gaps = 7/134 (5%)
 Frame = -1

Query: 189 LFGTTDAVVKHVLEGHDRGVNWAAFHPTMPLIVSGADDRQVKIWRMNESKAWEVDTCRGH 248
           L+   D + K    GH+  +N   + P      +G+DD   +++ +        D   G 
Sbjct: 381 LWDVRDGMCKQTFSGHESDINAITYFPNGHAFATGSDDATCRLFDI------RADQEIGM 220

Query: 249 Y--NNVSCAV----FHPRQELILSNSEDKSIRVWDMSKRTGVQTFRRDHDRFWVLAAHPN 302
           Y  +N+ C +    F     L+L   +D +  +WD+ K+          +R  VLA H N
Sbjct: 219 YSHDNIICGITSVAFSKSGRLLLGGYDDFNCNIWDVLKQ----------ERTGVLAGHDN 70

Query: 303 -LNLFAAGHDGGMI 315
            ++      DG  +
Sbjct: 69  RVSCLGVTEDGSAV 28

 Score = 37.0 bits (84), Expect = 0.047,   Method: Composition-based stats.
 Identities = 30/145 (20%), Positives = 55/145 (37%), Gaps = 3/145 (2%)
 Frame = -1

Query: 15  LSFHPKRPWILTSLHNGVIQLWDYRMCTLIDKFDEHDGPVRGIDFHKQQPLFVSGGDDYK 74
           LS  P     ++   +   +LWD R       F  H+  +  I +      F +G DD  
Sbjct: 441 LSLAPDMRTFVSGACDASAKLWDVRDGMCKQTFSGHESDINAITYFPNGHAFATGSDDAT 262

Query: 75  IKVWNYKLRRCLFTLLGHLDYI---RTTFFHHEYPWILSASDDQTIRVWNWQSRTCVCVL 131
            ++++ +  + +  +  H + I    +  F      +L   DD    +W+   +    VL
Sbjct: 261 CRLFDIRADQEI-GMYSHDNIICGITSVAFSKSGRLLLGGYDDFNCNIWDVLKQERTGVL 85

Query: 132 TGHNHYVMCAQFHPSEDLVVSASLD 156
            GH++ V C         V + S D
Sbjct: 84  AGHDNRVSCLGVTEDGSAVATGSWD 10

 Score = 36.2 bits (82), Expect = 0.085,   Method: Composition-based stats.
 Identities = 18/77 (23%), Positives = 36/77 (46%)
 Frame = -1

Query: 215 PTMPLIVSGADDRQVKIWRMNESKAWEVDTCRGHYNNVSCAVFHPRQELILSNSEDKSIR 274
           P M   VSGA D   K+W + +    +  T  GH ++++   + P      + S+D + R
Sbjct: 429 PDMRTFVSGACDASAKLWDVRDGMCKQ--TFSGHESDINAITYFPNGHAFATGSDDATCR 256

Query: 275 VWDMSKRTGVQTFRRDH 291
           ++D+     +  +  D+
Sbjct: 255 LFDIRADQEIGMYSHDN 205

 Score = 34.7 bits (78), Expect = 0.23,   Method: Composition-based stats.
 Identities = 27/104 (25%), Positives = 49/104 (47%), Gaps = 5/104 (4%)
 Frame = -1

Query: 66  FVSGGDDYKIKVWNYKLRRCLFTLLGHLDYIRT-TFFHHEYPWILSASDDQTIRVWNWQS 124
           FVSG  D   K+W+ +   C  T  GH   I   T+F + + +  + SDD T R+++ ++
Sbjct: 414 FVSGACDASAKLWDVRDGMCKQTFSGHESDINAITYFPNGHAFA-TGSDDATCRLFDIRA 238

Query: 125 RTCVCVLTGHNHYVMCA----QFHPSEDLVVSASLDQTVRVWDI 164
              + + +  N  ++C      F  S  L++    D    +WD+
Sbjct: 237 DQEIGMYSHDN--IICGITSVAFSKSGRLLLGGYDDFNCNIWDV 112
>20271
          Length = 567

 Score = 38.1 bits (87), Expect = 0.020,   Method: Compositional matrix adjust.
 Identities = 18/75 (24%), Positives = 35/75 (46%), Gaps = 6/75 (8%)
 Frame = -1

Query: 45  DKFDEHDGPVRGIDFHKQ------QPLFVSGGDDYKIKVWNYKLRRCLFTLLGHLDYIRT 98
           + ++ H GP+  ID H         P F++   D+ +K+WN K ++ + +   + DY+  
Sbjct: 303 EAYEGHQGPITAIDTHHAAGQIDFSPFFLTASFDWTVKLWNIKEQKYVCSFEDNSDYVSD 124

Query: 99  TFFHHEYPWILSASD 113
             +    P + S  D
Sbjct: 123 VQWSPTNPALFSCVD 79
>14500
          Length = 1238

 Score = 37.7 bits (86), Expect = 0.032,   Method: Compositional matrix adjust.
 Identities = 32/118 (27%), Positives = 54/118 (45%), Gaps = 5/118 (4%)
 Frame = +3

Query: 62  QQPLFVSGGD--DYKIKVWNYKLRRCLFTLLGHLDYIRTTFFHHEYPWILSA---SDDQT 116
           Q  L  SGG   D  I  WN      L ++      +    +  E+  ++S+   + +Q 
Sbjct: 237 QPSLLASGGGTADRHIHFWNCNTGTNLSSV-DTKSQVCALLWSKEHRELISSHGFAQNQL 413

Query: 117 IRVWNWQSRTCVCVLTGHNHYVMCAQFHPSEDLVVSASLDQTVRVWDISGLRKKNLSP 174
           I +W + + + V  LTGH   V+     P  + VVSA+ D+T+R+W    + K+   P
Sbjct: 414 I-IWKYPAMSRVAELTGHTARVLHMAMSPDGETVVSAAADETLRLWKCFTVDKEKKRP 584
>16105
          Length = 960

 Score = 37.4 bits (85), Expect = 0.038,   Method: Compositional matrix adjust.
 Identities = 40/153 (26%), Positives = 65/153 (42%), Gaps = 5/153 (3%)
 Frame = -2

Query: 130 VLTGHNHYVMCAQFHPSED-LVVSASLDQTVRVWDI--SGLRKKNLSPGAVESDVRGITG 186
           ++ GH   V+  Q+ P  D ++ SAS D TV+VW I  SGL                   
Sbjct: 590 LVAGHKGAVLDIQWCPHNDNVIASASDDCTVKVWQIPDSGL------------------- 468

Query: 187 VDLFGTTDAVVKHVLEGHDRGVNWAAFHPTMP-LIVSGADDRQVKIWRMNESKAW-EVDT 244
             +   TD VV   L GH +      +HP+   ++VS   D ++  W +   +   EVD 
Sbjct: 467 --VTNLTDPVVD--LVGHQKRCCLIVWHPSAQNVLVSAGADNKILFWNVGTGEPMLEVDV 300

Query: 245 CRGHYNNVSCAVFHPRQELILSNSEDKSIRVWD 277
                + + C  F+     ++   +DK +R+ D
Sbjct: 299 ----PDMIYCMSFNFNGSRLVCTCKDKKLRIID 213

 Score = 34.3 bits (77), Expect = 0.32,   Method: Compositional matrix adjust.
 Identities = 22/65 (33%), Positives = 32/65 (49%), Gaps = 8/65 (12%)
 Frame = -2

Query: 108 ILSASDDQTIRVWNWQSRTCVCVLT-------GHNHYVMCAQFHPS-EDLVVSASLDQTV 159
           I SASDD T++VW       V  LT       GH        +HPS ++++VSA  D  +
Sbjct: 527 IASASDDCTVKVWQIPDSGLVTNLTDPVVDLVGHQKRCCLIVWHPSAQNVLVSAGADNKI 348

Query: 160 RVWDI 164
             W++
Sbjct: 347 LFWNV 333
>33180
          Length = 460

 Score = 32.7 bits (73), Expect(2) = 0.092,   Method: Compositional matrix adjust.
 Identities = 20/71 (28%), Positives = 30/71 (42%), Gaps = 1/71 (1%)
 Frame = -2

Query: 15  LSFHPKRPWILTSLHNGVIQLWDYRMCTLIDKFDEHDGPVRGIDF-HKQQPLFVSGGDDY 73
           L F      I+   ++G + ++D        K D HD  V  + F      +  SGGDD 
Sbjct: 435 LMFSSDNTEIVGGANDGCLYVYDRESNQRTLKIDAHDDDVNAVAFADDSSQILYSGGDDG 256

Query: 74  KIKVWNYKLRR 84
             KVW+ +  R
Sbjct: 255 LCKVWDRRTLR 223

 Score = 21.9 bits (45), Expect(2) = 0.092,   Method: Compositional matrix adjust.
 Identities = 8/14 (57%), Positives = 12/14 (85%)
 Frame = -1

Query: 108 ILSASDDQTIRVWN 121
           +LS S DQTI++W+
Sbjct: 139 LLSNSKDQTIKLWD 98
>02090
          Length = 1841

 Score = 35.4 bits (80), Expect = 0.13,   Method: Compositional matrix adjust.
 Identities = 19/61 (31%), Positives = 26/61 (42%)
 Frame = -3

Query: 109  LSASDDQTIRVWNWQSRTCVCVLTGHNHYVMCAQFHPSEDLVVSASLDQTVRVWDISGLR 168
             S   D  I VW+  ++T V    GH     C    P    + +  LD TVR WD+   R
Sbjct: 1578 FSCCSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISPDGTKLWTGGLDNTVRSWDLREGR 1399

Query: 169  K 169
            +
Sbjct: 1398 Q 1396

 Score = 32.0 bits (71), Expect = 1.4,   Method: Compositional matrix adjust.
 Identities = 25/119 (21%), Positives = 44/119 (36%), Gaps = 1/119 (0%)
 Frame = -3

Query: 212  AFHPTMPLIVSGADDRQVKIWRMNESKAWEVDTCRGHYNNVSCAVFHPRQELILSNSEDK 271
            A  P   +  S   D  + +W ++      V   +GH +  SC    P    + +   D 
Sbjct: 1605 AISPDGKVCFSCCSDGNIAVWDLHNQTL--VRQFQGHTDGASCIDISPDGTKLWTGGLDN 1432

Query: 272  SIRVWDMSKRTGVQTFRRD-HDRFWVLAAHPNLNLFAAGHDGGMIVFKLERERPAYAVH 329
            ++R WD+  R G Q  + D   + + L   P     A G +   +      +   Y +H
Sbjct: 1431 TVRSWDL--REGRQLQQHDFSSQIFSLGYCPTGEWLAVGMESSNVEVLHHSKPDKYQLH 1261
>26107
          Length = 1338

 Score = 35.4 bits (80), Expect = 0.13,   Method: Compositional matrix adjust.
 Identities = 39/154 (25%), Positives = 64/154 (41%), Gaps = 13/154 (8%)
 Frame = -3

Query: 104  EYPWI------LSASDDQTIRVWNWQSRTCVCVLTGHNHYVMCAQFHPSEDL-VVSASLD 156
            +Y WI      L+AS DQT+ +W+ ++ T V    GH   V      PS      S + D
Sbjct: 1072 DYSWISNDSQCLTASGDQTVALWDVETTTKVTTFIGHKCSVRSVASCPSSPAQCASGARD 893

Query: 157  QTVRVWDISGLRKKNLSPGAVESDVRGITGVDLFGTTD------AVVKHVLEGHDRGVNW 210
              + +WD    +K+   P +    V   +G              A  K V++   + V  
Sbjct: 892  GHIMLWDSRVNKKREHQPCSQVHQVCPQSGHQSKPAKHRRIHRAAGPKGVMDTQ-QSVTC 716

Query: 211  AAFHPTMPLIVSGADDRQVKIWRMNESKAWEVDT 244
              +     +I SGA+D  VK+W   +++ W  +T
Sbjct: 715  VLYQTDNLIISSGANDGCVKMW---DTRKWYTNT 623
>21921
          Length = 1341

 Score = 35.4 bits (80), Expect = 0.13,   Method: Compositional matrix adjust.
 Identities = 24/70 (34%), Positives = 35/70 (50%), Gaps = 1/70 (1%)
 Frame = -1

Query: 91  GHLDYIRTTFFHHEYPWILSASDDQTIRVWNWQSRTCVCVLTGHNHYVMCAQFHPSEDL- 149
           GH   +R+        W++S SDD TIR W   S  C+  L      V    ++P+  L 
Sbjct: 489 GHTGIVRSICPDPTGQWLVSGSDDGTIRFWEVSSGRCMKTLQV-GGCVTSVAWNPNPSLC 313

Query: 150 VVSASLDQTV 159
           VV+A+L+ TV
Sbjct: 312 VVAATLNTTV 283
>17298
          Length = 476

 Score = 35.4 bits (80), Expect = 0.15,   Method: Composition-based stats.
 Identities = 14/37 (37%), Positives = 20/37 (54%)
 Frame = -1

Query: 246 RGHYNNVSCAVFHPRQELILSNSEDKSIRVWDMSKRT 282
           R H   V+C  F+    +ILS S D ++R WD   R+
Sbjct: 221 RDHAGTVNCVKFNEESTVILSGSLDNTVRAWDTRSRS 111

 Score = 33.5 bits (75), Expect = 0.49,   Method: Composition-based stats.
 Identities = 15/41 (36%), Positives = 23/41 (56%)
 Frame = -1

Query: 134 HNHYVMCAQFHPSEDLVVSASLDQTVRVWDISGLRKKNLSP 174
           H   V C +F+    +++S SLD TVR WD    R ++ +P
Sbjct: 215 HAGTVNCVKFNEESTVILSGSLDNTVRAWDT---RSRSHTP 102
>04358
          Length = 2430

 Score = 35.4 bits (80), Expect = 0.16,   Method: Compositional matrix adjust.
 Identities = 26/83 (31%), Positives = 40/83 (48%), Gaps = 17/83 (20%)
 Frame = +1

Query: 56   GIDFHKQQPLFV-------SGGDDYKIKVW--NYKLR---RCLF----TLLGHLDYIRTT 99
             +  +K +P +V       +GG D  +     N+ +R   RC      TL GH D I + 
Sbjct: 1261 SVSLYKTEPHYVLGLAAQHTGGADSLVAAASSNFMVRLYSRCRLAQTNTLTGHDDVISSI 1440

Query: 100  FFHHEYP-WILSASDDQTIRVWN 121
             F H  P  I++AS D T+R+W+
Sbjct: 1441 RFLHTDPGLIMTASHDHTVRIWD 1509

 Score = 33.1 bits (74), Expect = 0.67,   Method: Compositional matrix adjust.
 Identities = 18/57 (31%), Positives = 32/57 (56%), Gaps = 1/57 (1%)
 Frame = +1

Query: 108  ILSASDDQTIRVWNWQSRTCVCVLTGHNHYVMCAQF-HPSEDLVVSASLDQTVRVWD 163
            + +AS +  +R+++         LTGH+  +   +F H    L+++AS D TVR+WD
Sbjct: 1339 VAAASSNFMVRLYSRCRLAQTNTLTGHDDVISSIRFLHTDPGLIMTASHDHTVRIWD 1509
>28403
          Length = 428

 Score = 34.7 bits (78), Expect = 0.24,   Method: Composition-based stats.
 Identities = 18/35 (51%), Positives = 21/35 (60%)
 Frame = -1

Query: 1085 CEMAAYFTHSNLQPVHMILVLRTALNLFFKLKNFK 1119
            CE A  FTHSNLQ VH     RT + +F  LKN +
Sbjct: 182  CE*ACSFTHSNLQTVHKF--ARTFIYIFCSLKNIR 84
>15337
          Length = 860

 Score = 34.7 bits (78), Expect = 0.27,   Method: Compositional matrix adjust.
 Identities = 18/100 (18%), Positives = 44/100 (44%)
 Frame = -1

Query: 2   LTKFETKSARVKGLSFHPKRPWILTSLHNGVIQLWDYRMCTLIDKFDEHDGPVRGIDFHK 61
           L ++   +  +   +F P   ++     +G +++++Y    LI     + G +  + +  
Sbjct: 350 LYRWVVGTGAISEFAFSPCSRYLAVVGQDGHLRVFNYNSMELIGTMKSYFGGLLCVCWSP 171

Query: 62  QQPLFVSGGDDYKIKVWNYKLRRCLFTLLGHLDYIRTTFF 101
                V+GG+D  + VW++  +R +    GH  ++    F
Sbjct: 170 DGKYIVTGGEDDLVTVWSFHEKRVVCRGHGHKSWVNVVAF 51

 Score = 34.3 bits (77), Expect = 0.34,   Method: Compositional matrix adjust.
 Identities = 16/74 (21%), Positives = 34/74 (45%)
 Frame = -1

Query: 70  GDDYKIKVWNYKLRRCLFTLLGHLDYIRTTFFHHEYPWILSASDDQTIRVWNWQSRTCVC 129
           G D  ++V+NY     + T+  +   +    +  +  +I++  +D  + VW++  +  VC
Sbjct: 272 GQDGHLRVFNYNSMELIGTMKSYFGGLLCVCWSPDGKYIVTGGEDDLVTVWSFHEKRVVC 93

Query: 130 VLTGHNHYVMCAQF 143
              GH  +V    F
Sbjct: 92  RGHGHKSWVNVVAF 51
>04524
          Length = 1340

 Score = 33.9 bits (76), Expect = 0.38,   Method: Compositional matrix adjust.
 Identities = 18/57 (31%), Positives = 29/57 (50%), Gaps = 1/57 (1%)
 Frame = -1

Query: 226 DRQVKIWRMNESKAWEVDT-CRGHYNNVSCAVFHPRQELILSNSEDKSIRVWDMSKR 281
           DR  KI       A+ + T C GH   V+C V+     +++S S D ++R W+M  +
Sbjct: 971 DRDEKIRVSQFPNAYNIHTYCLGHTQFVNCLVYVEEFRVLISGSGDCTVRAWNMEGK 801

 Score = 33.9 bits (76), Expect = 0.42,   Method: Compositional matrix adjust.
 Identities = 22/81 (27%), Positives = 38/81 (46%), Gaps = 3/81 (3%)
 Frame = -1

Query: 89   LLGHLDYIRTTFFHHEYPWILSASDDQTIRVWNWQSRTCV---CVLTGHNHYVMCAQFHP 145
            LLGHL  +           +++   D+ IRV  + +   +   C+  GH  +V C  +  
Sbjct: 1040 LLGHLSMVLDVCLTGREGHVVTCDRDEKIRVSQFPNAYNIHTYCL--GHTQFVNCLVYVE 867

Query: 146  SEDLVVSASLDQTVRVWDISG 166
               +++S S D TVR W++ G
Sbjct: 866  EFRVLISGSGDCTVRAWNMEG 804

 Score = 32.3 bits (72), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 16/55 (29%), Positives = 28/55 (50%), Gaps = 1/55 (1%)
 Frame = -1

Query: 72  DYKIKVWNYKLRRCLFT-LLGHLDYIRTTFFHHEYPWILSASDDQTIRVWNWQSR 125
           D KI+V  +     + T  LGH  ++    +  E+  ++S S D T+R WN + +
Sbjct: 965 DEKIRVSQFPNAYNIHTYCLGHTQFVNCLVYVEEFRVLISGSGDCTVRAWNMEGK 801
>31474
          Length = 403

 Score = 33.5 bits (75), Expect = 0.57,   Method: Composition-based stats.
 Identities = 21/78 (26%), Positives = 30/78 (38%), Gaps = 13/78 (16%)
 Frame = -3

Query: 102 HHEYPW----------ILSASDDQTIRVWNWQSRTCVCVLT---GHNHYVMCAQFHPSED 148
           H E+ W          + S   D+ I++W  +    VC  T    H   V    + P  +
Sbjct: 308 HDEHAWCVAWNPTGTLLASCGSDKIIKIWGKEGDNWVCKSTLTDAHTRTVRSLGWSPCGN 129

Query: 149 LVVSASLDQTVRVWDISG 166
            + SAS D T  VW   G
Sbjct: 128 YLSSASFDATTAVWSRKG 75

 Score = 30.4 bits (67), Expect = 4.3,   Method: Composition-based stats.
 Identities = 24/85 (28%), Positives = 35/85 (41%), Gaps = 2/85 (2%)
 Frame = -3

Query: 201 LEGHDRGVNWAAFHPTMPLIVSGADDRQVKIWRMNESKAWEVDT--CRGHYNNVSCAVFH 258
           L  HD      A++PT  L+ S   D+ +KIW   E   W   +     H   V    + 
Sbjct: 317 LSAHDEHAWCVAWNPTGTLLASCGSDKIIKIWG-KEGDNWVCKSTLTDAHTRTVRSLGWS 141

Query: 259 PRQELILSNSEDKSIRVWDMSKRTG 283
           P    + S S D +  VW  S++ G
Sbjct: 140 PCGNYLSSASFDATTAVW--SRKGG 72
>10264
          Length = 416

 Score = 33.5 bits (75), Expect = 0.60,   Method: Composition-based stats.
 Identities = 20/65 (30%), Positives = 32/65 (49%), Gaps = 1/65 (1%)
 Frame = -1

Query: 102 HHEYPWILSASDDQTIRVWNWQSRTCVCVLTGHNHYVMCAQFHPSE-DLVVSASLDQTVR 160
           HH+   ++S   D    VW+ Q  T +    GH   ++  QF   + DLV++   D +V 
Sbjct: 212 HHD-ARLVSVGYDAEAFVWDVQKGTALAQFKGHMGRLLTCQFSGLDPDLVMTGGSDASVH 36

Query: 161 VWDIS 165
           VW +S
Sbjct: 35  VWRVS 21
>31864
          Length = 545

 Score = 32.7 bits (73), Expect = 0.99,   Method: Compositional matrix adjust.
 Identities = 21/84 (25%), Positives = 36/84 (42%), Gaps = 13/84 (15%)
 Frame = +2

Query: 205 DRGVNWAAFHPTMPLIVSGADDRQVKIWRMNESKAWEVDT-------------CRGHYNN 251
           +R VN AA  P +  +V G     +++     +KA + D+              +GH+  
Sbjct: 173 ERPVNSAAISPILDHVVLGGGQDAMEV-TTTSTKAGKFDSRFFHLIYEEEFARLKGHFGP 349

Query: 252 VSCAVFHPRQELILSNSEDKSIRV 275
           ++   FHP  +   S  ED  +RV
Sbjct: 350 INSLAFHPDGKSYASGGEDGFVRV 421
>10162
          Length = 1629

 Score = 32.3 bits (72), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 14/82 (17%), Positives = 35/82 (42%)
 Frame = +3

Query: 208 VNWAAFHPTMPLIVSGADDRQVKIWRMNESKAWEVDTCRGHYNNVSCAVFHPRQELILSN 267
           + W  +H    ++++G    +V +W++      ++   + H     C    P  + +   
Sbjct: 36  ITWLQWHGGAHVLLAGTQGGEVWLWQVPSQDYSKMKMLQSHGQPSLCGKILPNGKYVCVG 215

Query: 268 SEDKSIRVWDMSKRTGVQTFRR 289
             D  +++WD+   T V T++ 
Sbjct: 216 YSDGVVKLWDLKTGTAVHTWQH 281

 Score = 32.3 bits (72), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 43/198 (21%), Positives = 72/198 (36%), Gaps = 37/198 (18%)
 Frame = +3

Query: 19  PKRPWILTSLHNGVIQLWDYRMCTLIDKFD-----EHDGPVRG----------------- 56
           P   ++     +GV++LWD +  T +  +      E + P R                  
Sbjct: 189 PNGKYVCVGYSDGVVKLWDLKTGTAVHTWQHSVMPEEEMPERNSSDEEDGEEVEVEREED 368

Query: 57  ------IDFHKQQPLFVSGGDDYKIKVWNYKLRR--CLFTLLGHLD------YIRTTFFH 102
                 +D      L +SG  D   KV+N    +    F      D       + +  F 
Sbjct: 369 TVAILCVDCSADNALIMSGCADATAKVFNVSSGKLXSAFNCAASQDSQDKDNSVESVAFC 548

Query: 103 HEYPWILSASDDQTIRVWNWQSRTCVCVLTGHNHYVMCAQFHPSEDLVVSASLDQTVRVW 162
              P+  +A++  +++VW+  +         H   V   Q+  S  L+ +A LD  +RVW
Sbjct: 549 PVSPYAATATNSGSVQVWDLPTSVARHSFQ-HPEGVCKLQWSSSTALLYTACLDGVMRVW 725

Query: 163 DI-SGLRKKNLSPGAVES 179
           D  SG  K  L+  A  S
Sbjct: 726 DARSGASKAVLTGHARNS 779

 Score = 31.6 bits (70), Expect = 1.9,   Method: Compositional matrix adjust.
 Identities = 28/123 (22%), Positives = 46/123 (37%), Gaps = 2/123 (1%)
 Frame = +3

Query: 41  CTLIDKFDEHDGPVRGIDFHKQQPLFVSGGDDYKIKVWNYKLRRCLFTLLGHLDYIRTTF 100
           C       + D  V  + F    P   +  +   ++VW+        +   H + +    
Sbjct: 489 CAASQDSQDKDNSVESVAFCPVSPYAATATNSGSVQVWDLPTSVARHSFQ-HPEGVCKLQ 665

Query: 101 FHHEYPWILSASDDQTIRVWNWQSRTCVCVLTGHNHYVMCAQFHPSED--LVVSASLDQT 158
           +      + +A  D  +RVW+ +S     VLTGH        F  + D   +VS S D T
Sbjct: 666 WSSSTALLYTACLDGVMRVWDARSGASKAVLTGHARNSCILDFDVTRDGTCLVSGSEDGT 845

Query: 159 VRV 161
            RV
Sbjct: 846 ARV 854
>06576
          Length = 1547

 Score = 32.3 bits (72), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 32/127 (25%), Positives = 54/127 (42%), Gaps = 3/127 (2%)
 Frame = -2

Query: 39   RMCTLIDKFDEHDGPVRGIDFHKQQPLFVSGGDDYKIKVWNYKLRRCLFTLLGHLDYIRT 98
            R+  +  +F E D  ++G+D+   + + +  G    +    +     L +L  HL +   
Sbjct: 1327 RVSVVSCRFQEEDIDIQGLDYSVVKDVQMDQG----VSCLAWSPSTSLSSLDKHLCFA-- 1166

Query: 99   TFFHHEYPWILSASDDQTIRVWNWQSRTC--VCVLTGHNHYVMCAQFHPS-EDLVVSASL 155
                       +A DD ++RV+    +T     V+ GH  +V    F P+ ED V S   
Sbjct: 1165 -----------AACDDHSVRVFTSDLKTTNKTHVVKGHTDFVNSVTFSPTEEDQVXSTGD 1019

Query: 156  DQTVRVW 162
            D T RVW
Sbjct: 1018 DLTCRVW 998
>05493
          Length = 1292

 Score = 32.3 bits (72), Expect = 1.4,   Method: Compositional matrix adjust.
 Identities = 24/67 (35%), Positives = 33/67 (49%), Gaps = 2/67 (2%)
 Frame = -2

Query: 1064 LCMEIERKKLPKETLDQQ--KRICEMAAYFTHSNLQPVHMILVLRTALNLFFKLKNFKTA 1121
            L ME+ER  L  E +D+Q   R+C            P +  L LR A++L+ K K F  A
Sbjct: 691  LMMEVERLDLAMEYVDEQAYSRVCLYLTSCVAYVPDPENTAL-LRCAVDLYRKFKQFPQA 515

Query: 1122 ATFARRL 1128
              FA +L
Sbjct: 514  LRFALQL 494
>31054
          Length = 392

 Score = 31.6 bits (70), Expect = 1.8,   Method: Compositional matrix adjust.
 Identities = 26/106 (24%), Positives = 49/106 (46%), Gaps = 9/106 (8%)
 Frame = -2

Query: 66  FVSGGDDYKIKVWNYKLRRCLFTLLGHLDYIRTTFFHHEYPWILSASDDQTIRVWNWQS- 124
           F  G  D  +K W +     +  L GH   I T   + +   ++S +D+ T+ +W+W++ 
Sbjct: 367 FAXGSPD-XVKQWKFPDGNFIQNLSGHNAIINTLAVNSDGV-LVSGADNGTMHLWDWRTG 194

Query: 125 ----RTCVCVLTG----HNHYVMCAQFHPSEDLVVSASLDQTVRVW 162
               R    V  G     + +  C  F  SE  +++A  D+T++V+
Sbjct: 193 YNFQRIHAAVQPGSLDSESGFFACT-FDQSESRLITAEADKTIKVY 59
>12140
          Length = 727

 Score = 31.6 bits (70), Expect = 1.8,   Method: Composition-based stats.
 Identities = 29/106 (27%), Positives = 47/106 (44%), Gaps = 8/106 (7%)
 Frame = +2

Query: 221 VSGADDRQVKIWRMNESKAWEVDTCRGHYNNVSCAVFHPR----QELILSNSEDKSIRVW 276
           VSG  D  VKIWR +E+   E     GH + V    + P     + +I S S+D  + +W
Sbjct: 272 VSGGCDNLVKIWREDETGWVEDQKLEGHSDWVRDVAWAPSIGLPRNVIASCSQDCRVIIW 451

Query: 277 DMSKRTGVQTFR---RDHDRFWVLAAHPNLNLFA-AGHDGGMIVFK 318
                +   T R   +  D  W ++     N+ A +G D  + ++K
Sbjct: 452 TNDGSSNQWTSRILNKFSDVVWHVSWSVTGNILAVSGGDNKVTLWK 589
>38177
          Length = 430

 Score = 31.6 bits (70), Expect = 2.3,   Method: Compositional matrix adjust.
 Identities = 14/55 (25%), Positives = 26/55 (47%)
 Frame = +3

Query: 3   TKFETKSARVKGLSFHPKRPWILTSLHNGVIQLWDYRMCTLIDKFDEHDGPVRGI 57
           T  +     V+ + +     W++T+ H+G I+ W   M   +  F  H  P+RG+
Sbjct: 96  TILQAHDVSVRAMRWSNHDQWMVTADHSGYIKYWQSNM-NNVKMFQGHKEPIRGV 257
>04088
          Length = 511

 Score = 31.2 bits (69), Expect = 2.8,   Method: Compositional matrix adjust.
 Identities = 19/58 (32%), Positives = 30/58 (51%), Gaps = 2/58 (3%)
 Frame = +3

Query: 109 LSASDDQTIRVWNWQSRTCVCVLTGHNH--YVMCAQFHPSEDLVVSASLDQTVRVWDI 164
           L +S D T+R+ +  +   +   TGH H  Y + +  +  + LVVS S D  V  WD+
Sbjct: 78  LVSSQDNTVRLMDKDTGEMLNEFTGHKHSQYKIDSCLNNEDTLVVSGSEDGKVYFWDL 251
>01598
          Length = 1545

 Score = 30.8 bits (68), Expect = 3.2,   Method: Compositional matrix adjust.
 Identities = 20/65 (30%), Positives = 32/65 (49%), Gaps = 1/65 (1%)
 Frame = +1

Query: 102  HHEYPWILSASDDQTIRVWNWQSRTCVCVLTGHNHYVMCAQFHPSE-DLVVSASLDQTVR 160
            HH+   ++S   D    VW+ Q  T +    GH   ++  QF   + DLV++   D +V 
Sbjct: 1333 HHDAR-LVSVGYDAEAFVWDVQKGTALAQFKGHMGRLLTCQFSGLDPDLVMTGGSDASVH 1509

Query: 161  VWDIS 165
            VW +S
Sbjct: 1510 VWRVS 1524
>36111
          Length = 687

 Score = 30.8 bits (68), Expect = 3.4,   Method: Composition-based stats.
 Identities = 13/37 (35%), Positives = 19/37 (51%), Gaps = 2/37 (5%)
 Frame = +2

Query: 53  PVRGIDFHKQQPLFVSGGDDYKIKVWN--YKLRRCLF 87
           PV  + FH     F +GG D  + +W+  +K R C F
Sbjct: 236 PVNAVAFHNVYNTFATGGSDGYVNIWDGFHKKRLCXF 346
>13509
          Length = 572

 Score = 30.4 bits (67), Expect = 4.0,   Method: Compositional matrix adjust.
 Identities = 15/56 (26%), Positives = 25/56 (44%)
 Frame = +2

Query: 12  VKGLSFHPKRPWILTSLHNGVIQLWDYRMCTLIDKFDEHDGPVRGIDFHKQQPLFV 67
           V  +SFHP    + T   +G    WD    T +   ++ D P+   +F+ Q  +F 
Sbjct: 368 VNDISFHPVHGTLSTVGSDGRFSFWDKDARTKLKTSEQFDQPITTCNFNAQGNIFA 535
>25880
          Length = 423

 Score = 30.4 bits (67), Expect = 4.9,   Method: Composition-based stats.
 Identities = 19/76 (25%), Positives = 38/76 (50%)
 Frame = +2

Query: 204 HDRGVNWAAFHPTMPLIVSGADDRQVKIWRMNESKAWEVDTCRGHYNNVSCAVFHPRQEL 263
           H   V   AF  +   IV+G++++ V+++ + +  A E +   GH   +       ++ L
Sbjct: 53  HKHIVKSVAFDNSSENIVTGSNEKLVRVFNLEQPDA-EPELYGGHTGAI-------KRAL 208

Query: 264 ILSNSEDKSIRVWDMS 279
             S SED ++R+W  +
Sbjct: 209 YASGSEDGTLRLWQTT 256
>01249
          Length = 1743

 Score = 29.6 bits (65), Expect = 7.1,   Method: Compositional matrix adjust.
 Identities = 17/55 (30%), Positives = 25/55 (45%)
 Frame = -1

Query: 198 KHVLEGHDRGVNWAAFHPTMPLIVSGADDRQVKIWRMNESKAWEVDTCRGHYNNV 252
           + VL+GH   V   AF      + SG+ + +V IW M    +  +D   G   NV
Sbjct: 936 ERVLQGHSDAVTCLAFSSDGQRLASGSQNGKVIIWNMESGDSTSLDI-SGAVGNV 775
>07781
          Length = 1269

 Score = 29.6 bits (65), Expect = 7.1,   Method: Compositional matrix adjust.
 Identities = 16/52 (30%), Positives = 24/52 (46%)
 Frame = -2

Query: 227 RQVKIWRMNESKAWEVDTCRGHYNNVSCAVFHPRQELILSNSEDKSIRVWDM 278
           R+   WR ++ +AW             CA      ELI S S+D  ++VWD+
Sbjct: 821 RETSQWRAHDFEAW------------ICAFDQWNTELIYSGSDDCKLKVWDL 702
>30297
          Length = 822

 Score = 29.6 bits (65), Expect = 7.7,   Method: Composition-based stats.
 Identities = 10/35 (28%), Positives = 23/35 (65%)
 Frame = -1

Query: 242 VDTCRGHYNNVSCAVFHPRQELILSNSEDKSIRVW 276
           + + RGH  +VSC     + +++L+++ D ++R+W
Sbjct: 249 IQSWRGHVESVSCLDLVEQNKVLLTSAADCTVRMW 145
>11915
          Length = 737

 Score = 29.3 bits (64), Expect = 9.8,   Method: Composition-based stats.
 Identities = 20/87 (22%), Positives = 39/87 (44%), Gaps = 5/87 (5%)
 Frame = +1

Query: 74  KIKVWNYKLRRCLFTLLGHLDYIRTTFFHHEYPW-ILSASDDQTIRVWNWQSR-TC---V 128
           +IK+WN +  + L  ++ H   +    F  +    ++SAS D T+++W +  +  C   +
Sbjct: 475 RIKLWNCETGKLLIEMMDHKATVHDLHFAADNSLCLMSASHDGTVKLWEFDDQGDCNMYL 654

Query: 129 CVLTGHNHYVMCAQFHPSEDLVVSASL 155
            + T   H   C   H    +  + SL
Sbjct: 655 TLRTNAKHAFSCRWSHDRRYVATAGSL 735
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|33563240|ref|NP_033736.1| actin, alpha 1, skeletal
muscle [Mus musculus]
         (377 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

04742                                                                 740   0.0  
39562                                                                 599   e-172
02757                                                                 294   e-121
12322                                                                 238   4e-63
00608                                                                 199   1e-51
01436                                                                 169   1e-42
11487                                                                  95   8e-42
19721                                                                 100   4e-33
36954                                                                 123   1e-28
32273                                                                 122   2e-28
18926                                                                 110   2e-25
13361                                                                  92   2e-19
17032                                                                  37   0.019
06084                                                                  28   7.5  
>04742
          Length = 2111

 Score =  740 bits (1911), Expect = 0.0,   Method: Compositional matrix adjust.
 Identities = 351/377 (93%), Positives = 360/377 (95%)
 Frame = +2

Query: 1   MCDEDETTALVCDNGSGLVKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEA 60
           MCDED   ALV DNGSG+ KAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEA
Sbjct: 92  MCDED-VAALVIDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEA 268

Query: 61  QSKRGILTLKYPIEHGIITNWDDMEKIWHHTFYNELRVAPEEHPTLLTEAPLNPKANREK 120
           QSKRGILTLKYPIEHGI+TNWDDMEKIWHHTFYNELRVAPEEHP LLTEAPLNPKANREK
Sbjct: 269 QSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREK 448

Query: 121 MTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIMRL 180
           MTQIMFETFN PAMYVAIQAVLSLYASGRTTGIVLDSGDGV H VPIYEGYALPHAI RL
Sbjct: 449 MTQIMFETFNSPAMYVAIQAVLSLYASGRTTGIVLDSGDGVXHTVPIYEGYALPHAISRL 628

Query: 181 DLAGRDLTDYLMKILTERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATAASSSSLEK 240
           DLAGRDLTDYLMKILTERGYSF TTAEREIVRDIKEKLCYVALDFE EM TAASSSSLEK
Sbjct: 629 DLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMQTAASSSSLEK 808

Query: 241 SYELPDGQVITIGNERFRCPETLFQPSFIGMESAGIHETTYNSIMKCDIDIRKDLYANNV 300
           SYELPDGQVITIGNERFRCPE +FQPSF+GMESAG HETTYNSIMKCD+DIRKDLYAN V
Sbjct: 809 SYELPDGQVITIGNERFRCPEAMFQPSFLGMESAGXHETTYNSIMKCDVDIRKDLYANTV 988

Query: 301 MSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWIT 360
           +SGG+TMYPGIADRMQKEITALAP TMKIKIIAPPERKYSVWIGGSILASLSTFQQMWI+
Sbjct: 989 LSGGSTMYPGIADRMQKEITALAPPTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWIS 1168

Query: 361 KQEYDEAGPSIVHRKCF 377
           KQEYDE+GPSIVHRKCF
Sbjct: 1169KQEYDESGPSIVHRKCF 1219
>39562
          Length = 1438

 Score =  599 bits (1545), Expect = e-172,   Method: Compositional matrix adjust.
 Identities = 283/301 (94%), Positives = 291/301 (96%)
 Frame = -2

Query: 77   IITNWDDMEKIWHHTFYNELRVAPEEHPTLLTEAPLNPKANREKMTQIMFETFNVPAMYV 136
            I+TNWDDMEKIWHHTFYNELRVAPEEHP LLTEAPLNPKANREKMTQIMFETFN PAMYV
Sbjct: 1437 IVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNSPAMYV 1258

Query: 137  AIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDYLMKILT 196
            AIQAVLSLYASGRTTGIVLDSGDGVTH VPIYEGYALPHAIMRLDLAGRDLTDYLMKILT
Sbjct: 1257 AIQAVLSLYASGRTTGIVLDSGDGVTHTVPIYEGYALPHAIMRLDLAGRDLTDYLMKILT 1078

Query: 197  ERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATAASSSSLEKSYELPDGQVITIGNER 256
            ERGYSF TTAEREIVRDIKEKL YVALDFE EM TAASSSSLEKSYELPDGQVITIGNER
Sbjct: 1077 ERGYSFTTTAEREIVRDIKEKLDYVALDFEQEMLTAASSSSLEKSYELPDGQVITIGNER 898

Query: 257  FRCPETLFQPSFIGMESAGIHETTYNSIMKCDIDIRKDLYANNVMSGGTTMYPGIADRMQ 316
            FRCPE +FQPSF+GMESAGIHETTYNSIMKCD+DIRKDLYAN V+SGG+TMYPGIADRMQ
Sbjct: 897  FRCPEAMFQPSFLGMESAGIHETTYNSIMKCDVDIRKDLYANTVLSGGSTMYPGIADRMQ 718

Query: 317  KEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWITKQEYDEAGPSIVHRKC 376
            KEITALAP TMKIKIIAPPERKYSVWIGGSILASLSTFQQMWI+KQEYDE+GPSIVHRKC
Sbjct: 717  KEITALAPPTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKC 538

Query: 377  F 377
            F
Sbjct: 537  F 535
>02757
          Length = 1094

 Score =  294 bits (753), Expect(3) = e-121,   Method: Compositional matrix adjust.
 Identities = 140/151 (92%), Positives = 146/151 (96%)
 Frame = -2

Query: 174 PHAIMRLDLAGRDLTDYLMKILTERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATAA 233
           P AI+RLDLAGRDLTDYLMKILTERGYSF TTAEREIV DIKEKLCYVALDFE EMATAA
Sbjct: 997 PTAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVXDIKEKLCYVALDFEQEMATAA 818

Query: 234 SSSSLEKSYELPDGQVITIGNERFRCPETLFQPSFIGMESAGIHETTYNSIMKCDIDIRK 293
           SSSSLEKSYELPDGQVITIGNERFRCPE+LFQPSF+GMESAGIHETTYNSIMKCD+DIRK
Sbjct: 817 SSSSLEKSYELPDGQVITIGNERFRCPESLFQPSFLGMESAGIHETTYNSIMKCDVDIRK 638

Query: 294 DLYANNVMSGGTTMYPGIADRMQKEITALAP 324
           DLYAN V+SGGTTM+PGIADRMQKEITALAP
Sbjct: 637 DLYANTVLSGGTTMFPGIADRMQKEITALAP 545

 Score =  109 bits (273), Expect(3) = e-121,   Method: Compositional matrix adjust.
 Identities = 50/53 (94%), Positives = 52/53 (98%)
 Frame = -3

Query: 325 STMKIKIIAPPERKYSVWIGGSILASLSTFQQMWITKQEYDEAGPSIVHRKCF 377
           STMKIK IAPPERKYSVWIGGSILASLSTFQQMWI+KQEYDE+GPSIVHRKCF
Sbjct: 543 STMKIKXIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF 385

 Score = 70.5 bits (171), Expect(3) = e-121,   Method: Compositional matrix adjust.
 Identities = 33/34 (97%), Positives = 33/34 (97%)
 Frame = -1

Query: 142  LSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPH 175
            LSLYASGRTTGIVLDSGDGVTH VPIYEGYALPH
Sbjct: 1094 LSLYASGRTTGIVLDSGDGVTHTVPIYEGYALPH 993
>12322
          Length = 849

 Score =  238 bits (606), Expect = 4e-63,   Method: Compositional matrix adjust.
 Identities = 112/217 (51%), Positives = 150/217 (69%)
 Frame = +1

Query: 161 VTHNVPIYEGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFVTTAEREIVRDIKEKLCY 220
           VTH VP+YEG+A+PH+IMR+D+AGRD+T YL  +L + G    TTAE E+V+ IKE+ CY
Sbjct: 1   VTHAVPVYEGFAMPHSIMRVDVAGRDVTRYLRLLLRKEGMDLHTTAEFEVVKHIKERTCY 180

Query: 221 VALDFENEMATAASSSSLEKSYELPDGQVITIGNERFRCPETLFQPSFIGMESAGIHETT 280
           ++++   E     S  + + SY LPDG  + +G  RFR PE LF+P  IG E  GIHE  
Sbjct: 181 LSINPLKE----ESVDTEKVSYTLPDGNTVEVGPARFRAPELLFRPDLIGEECEGIHEVL 348

Query: 281 YNSIMKCDIDIRKDLYANNVMSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYS 340
             SI K D+D+RK LY+N V+SGG+T++ G  DR+  E+  LAP  +KI+I AP ER YS
Sbjct: 349 SYSIQKSDVDLRKTLYSNIVLSGGSTLFKGFGDRLLSELKKLAPKDIKIRISAPQERLYS 528

Query: 341 VWIGGSILASLSTFQQMWITKQEYDEAGPSIVHRKCF 377
            WIG SILASL TF++MW++K+EY E G   +HRK F
Sbjct: 529 TWIGXSILASLDTFRKMWVSKREYHEEGVKAIHRKTF 639
>00608
          Length = 1930

 Score =  199 bits (507), Expect = 1e-51,   Method: Compositional matrix adjust.
 Identities = 124/333 (37%), Positives = 181/333 (54%), Gaps = 32/333 (9%)
 Frame = +3

Query: 77  IITNWDDMEKIWHHTFYNELRVAPEEHPTLLTEAPLNPKANREKMTQIMFETFNVPAMYV 136
           II +WD ME+ +    +  LR  PE+H  LLTE PLN   NRE   +IMFE+FNVP +Y+
Sbjct: 3   IIDDWDLMERFYEQVIFKYLRAEPEDHYFLLTEPPLNTPENREYTAEIMFESFNVPGLYI 182

Query: 137 AIQAVLSLYASGRT--------TGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLT 188
           A+QAVL+L AS  +        TG V+DSGDGVTH +P+ EGY +   I  + +AGRD+T
Sbjct: 183 AVQAVLALAASWTSRNVGERTLTGTVIDSGDGVTHVIPVAEGYVIGSCIKHIPIAGRDIT 362

Query: 189 DYLMKILTERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATAASS-SSLEKSYELPD- 246
            ++ ++L ER          E  + IKE+  YV  D   E +   +  S   K YE  + 
Sbjct: 363 YFIQQLLREREVGIPPEQSLETAKAIKERFSYVCPDIAKEFSKYDTDPSKWMKKYEGRNT 542

Query: 247 --GQV--ITIGNERFRCPETLFQPSFIGME-SAGIHETTYNSIMKCDIDIRKDLYANNVM 301
              Q+  + +G ERF  PE  F P F   + +  I +   + I  C ID+R+ LY N V+
Sbjct: 543 ISKQLFSVDVGYERFLGPEIFFHPEFSNPDFTMPISDVVDDVIQNCPIDVRRGLYKNIVL 722

Query: 302 SGGTTMYPGIADRMQKEIT----------------ALAPSTMKIKIIAPPERKYSVWIGG 345
           SGG+TM+     ++Q+++                  + P  +++++I    ++Y+VW GG
Sbjct: 723 SGGSTMFRDFGRKIQRDVKRVVDGRLKASEELSQGRIKPKPIEVQVITHHMQRYAVWFGG 902

Query: 346 SILASLSTFQQMWITKQEYDEAGPSIV-HRKCF 377
           S+LAS   F Q+  TK +YDE GPSI  H   F
Sbjct: 903 SMLASTPEFYQVCHTKADYDEHGPSICRHNPVF 1001
>01436
          Length = 2563

 Score =  169 bits (429), Expect = 1e-42,   Method: Compositional matrix adjust.
 Identities = 84/200 (42%), Positives = 121/200 (60%), Gaps = 12/200 (6%)
 Frame = +3

Query: 187 LTDYLMKILTERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATAASSSSLEKSYELPD 246
           +T YL+K+L  RGY+F  +A+ E VR +KEKLCY A D E E   A  ++ L + Y LPD
Sbjct: 3   ITRYLIKLLLLRGYAFNHSADFETVRMLKEKLCYTAYDVEQEQKLALETTVLVEPYILPD 182

Query: 247 GQVITIGNERFRCPETLFQPSFIGMESAGIHETTYNSIMKCDIDIRKDLYANNVMSGGTT 306
           G+VI +G ERF  PE LFQP  I ++  G+ E  +N+I   D+DIR D Y + V+SGG+T
Sbjct: 183 GRVIKVGGERFEAPEALFQPHLINVDGVGVAELLFNTIQAADMDIRPDFYKHIVLSGGST 362

Query: 307 MYPGIADRMQKEITAL-----------APSTMKIKIIAPPERKYSVWIGGSILAS-LSTF 354
           MYPG+  R+++EI  L             S  KI+I  PP RK+ V++GGS+ A  +   
Sbjct: 363 MYPGLPSRLEREIKQLYLERVLXGDTSRLSKFKIRIEDPPRRKHMVFLGGSVXADIMKDK 542

Query: 355 QQMWITKQEYDEAGPSIVHR 374
              W+ + EY+E G  ++ +
Sbjct: 543 DDFWMMRSEYEEMGVKVLDK 602
>11487
          Length = 771

 Score = 95.1 bits (235), Expect(3) = 8e-42,   Method: Compositional matrix adjust.
 Identities = 41/43 (95%), Positives = 43/43 (100%)
 Frame = -2

Query: 335 PERKYSVWIGGSILASLSTFQQMWITKQEYDEAGPSIVHRKCF 377
           PERKYSVWIGGSILASLSTFQQMWI+KQEYDE+GPSIVHRKCF
Sbjct: 602 PERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF 474

 Score = 82.4 bits (202), Expect(3) = 8e-42,   Method: Compositional matrix adjust.
 Identities = 36/41 (87%), Positives = 39/41 (95%)
 Frame = -1

Query: 278 ETTYNSIMKCDIDIRKDLYANNVMSGGTTMYPGIADRMQKE 318
           ET YNSIMKCD+DIRKDLYAN V+SGGTTM+PGIADRMQKE
Sbjct: 771 ETAYNSIMKCDVDIRKDLYANTVLSGGTTMFPGIADRMQKE 649

 Score = 32.0 bits (71), Expect(3) = 8e-42,   Method: Compositional matrix adjust.
 Identities = 15/18 (83%), Positives = 16/18 (88%)
 Frame = -3

Query: 317 KEITALAPSTMKIKIIAP 334
           + ITALAP TMKIKIIAP
Sbjct: 655 ERITALAPPTMKIKIIAP 602
>19721
          Length = 757

 Score =  100 bits (248), Expect(2) = 4e-33,   Method: Compositional matrix adjust.
 Identities = 56/120 (46%), Positives = 77/120 (64%), Gaps = 8/120 (6%)
 Frame = +2

Query: 77  IITNWDDMEKIWHHTFYNELRVAPEEHPTLLTEAPLNPKANREKMTQIMFETFNVPAMYV 136
           ++ +WD  E+      +  LR  PE+H  LLTE PLN   NRE   +IMFETFN+P +Y+
Sbjct: 2   VVEDWDLHERFMEQAIFKYLRAEPEDHYFLLTEPPLNTPENREFTAEIMFETFNIPGLYI 181

Query: 137 AIQAVLSLYASGRT--------TGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLT 188
           A+QAVL+L AS  +        TG V+DSGDGVTH +P+ +GY +  AI  + +AGRD+T
Sbjct: 182 AVQAVLALAASWTSRPPNERTLTGTVIDSGDGVTHVIPVVDGYVIGSAIKHIPIAGRDIT 361

 Score = 59.3 bits (142), Expect(2) = 4e-33,   Method: Compositional matrix adjust.
 Identities = 37/108 (34%), Positives = 52/108 (48%), Gaps = 8/108 (7%)
 Frame = +3

Query: 209 EIVRDIKEKLCYVALDFENEMATAAS-------SSSLEKSYELPDGQVITIGNERFRCPE 261
           E  + IKE+  YV  D   E A   S       +  +  S + PD     +G E+F  PE
Sbjct: 420 EAAKQIKERYSYVCPDIAKEFAKYDSDPEKWIKAHKMSGSSKYPDFS-FDVGYEKFLGPE 596

Query: 262 TLFQPSFI-GMESAGIHETTYNSIMKCDIDIRKDLYANNVMSGGTTMY 308
             F+P F+ G   A I +     I  C ID R+ LY N V+SGG++M+
Sbjct: 597 VFFRPEFVNGDFQASISDVVDTVIQSCPIDSRRPLYNNIVLSGGSSMF 740
>36954
          Length = 892

 Score =  123 bits (308), Expect = 1e-28,   Method: Compositional matrix adjust.
 Identities = 67/189 (35%), Positives = 106/189 (56%), Gaps = 9/189 (4%)
 Frame = -1

Query: 5   DETTALVCDNGSGLVKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKR 64
           DE  ALV D GS   +AG+AG+D P+A  P+ VG        +     D+    E +   
Sbjct: 817 DEVGALVFDIGSYSFRAGYAGEDTPKAEIPTHVGVMEDIETTMDTDGGDAPPQPEKKYLI 638

Query: 65  GILTLKYP---------IEHGIITNWDDMEKIWHHTFYNELRVAPEEHPTLLTEAPLNPK 115
             + +K+P         ++ G++ +WD  EK+  + +   ++     HP L++E   N K
Sbjct: 637 DTVYMKHPRKGMHLNSFLKDGMVEDWDMFEKVIDYAYNRSIKSESCLHPLLMSEPAWNTK 458

Query: 116 ANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPH 175
           A REK+T+IMFE +N+PA ++   +VLS +A+GR+T ++LDSG   T  VP+Y+GY L  
Sbjct: 457 AKREKLTEIMFEKYNIPAFFLRKNSVLSAFANGRSTALILDSGATHTSAVPVYDGYVLTQ 278

Query: 176 AIMRLDLAG 184
            I++  LAG
Sbjct: 277 GIVKSPLAG 251
>32273
          Length = 265

 Score =  122 bits (306), Expect = 2e-28,   Method: Compositional matrix adjust.
 Identities = 50/88 (56%), Positives = 74/88 (84%), Gaps = 1/88 (1%)
 Frame = -2

Query: 66  ILTLKYPIEHGIITNWDDMEKIWHHTF-YNELRVAPEEHPTLLTEAPLNPKANREKMTQI 124
           +++++YP+EHGI+ +W+DME+IW + +  ++L+   EEHP LLTEAPLNP+ NREK  +I
Sbjct: 264 LMSIRYPMEHGIVKDWNDMERIWQYIYSKDQLQTFSEEHPVLLTEAPLNPRRNREKAAEI 85

Query: 125 MFETFNVPAMYVAIQAVLSLYASGRTTG 152
            F+TFNVPA+++++QAVLSLYA+GR TG
Sbjct: 84  FFDTFNVPALFISMQAVLSLYATGRITG 1
>18926
          Length = 478

 Score =  110 bits (275), Expect(2) = 2e-25,   Method: Compositional matrix adjust.
 Identities = 49/105 (46%), Positives = 69/105 (65%), Gaps = 3/105 (2%)
 Frame = +1

Query: 275 GIHETTYNSIMKCDIDIRKDLYANNVMSGGTTMYPGIADRMQKEITALAPSTMKIKIIAP 334
           G+      S+  CDIDIR  LY   +  GG ++  G  +R+ ++++   P +M++KIIA 
Sbjct: 97  GVGHVVTTSVGMCDIDIRPSLYGGVIAVGGNSLIQGFTERLNRDLSNKTPPSMRLKIIAA 276

Query: 335 P---ERKYSVWIGGSILASLSTFQQMWITKQEYDEAGPSIVHRKC 376
               ER++S WIGGSILASL +FQQMW++KQEY+E G S V RKC
Sbjct: 277 ASTAERRFSSWIGGSILASLGSFQQMWVSKQEYEEGGKSCVERKC 411

 Score = 22.7 bits (47), Expect(2) = 2e-25,   Method: Compositional matrix adjust.
 Identities = 13/28 (46%), Positives = 15/28 (53%), Gaps = 4/28 (14%)
 Frame = +3

Query: 252 IGNERFRCPETLFQPSFI----GMESAG 275
             +ERF+  E LF PS I    G  SAG
Sbjct: 15  FASERFKVCEGLFDPSVIKESQGNSSAG 98
>13361
          Length = 1217

 Score = 92.4 bits (228), Expect = 2e-19,   Method: Compositional matrix adjust.
 Identities = 57/176 (32%), Positives = 84/176 (47%), Gaps = 23/176 (13%)
 Frame = +3

Query: 219 CYVALDFENEMATAASS-SSLEKSYE-----LPDGQVITIGNERFRCPETLFQPSFIGME 272
           CY+  D   E A   S  S   ++Y            + +G ERF  PE  F P F   +
Sbjct: 42  CYICPDIAKEFAKYDSEPSKWIRNYTGMNTVTKQAFNVDVGYERFLGPEIFFHPEFSNPD 221

Query: 273 -SAGIHETTYNSIMKCDIDIRKDLYANNVMSGGTTMYPGIADRMQKEITA---------- 321
            +  + E   N I  C ID+R+ LY N V+SGG+TM+     R+Q++I            
Sbjct: 222 FTIPLSEIVDNVIQNCPIDVRRHLYNNIVLSGGSTMFKDFGRRLQRDIKRSVDTRLRISE 401

Query: 322 ------LAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWITKQEYDEAGPSI 371
                 + P  + +++I    ++Y+VW GGS+LAS   F Q+  TK  Y+E GPSI
Sbjct: 402 NLSEGRIKPKPIDVQVITHHMQRYAVWFGGSMLASTPEFYQVCHTKAAYEEYGPSI 569
>17032
          Length = 2938

 Score = 36.6 bits (83), Expect = 0.019,   Method: Compositional matrix adjust.
 Identities = 17/30 (56%), Positives = 20/30 (66%)
 Frame = -1

Query: 343  IGGSILASLSTFQQMWITKQEYDEAGPSIV 372
             GGS+LAS   F Q+  TK +YDE GPSI 
Sbjct: 2938 FGGSMLASTPEFYQVCHTKADYDEHGPSIC 2849
>06084
          Length = 1739

 Score = 27.7 bits (60), Expect = 7.5,   Method: Compositional matrix adjust.
 Identities = 11/18 (61%), Positives = 13/18 (72%)
 Frame = +3

Query: 335 PERKYSVWIGGSILASLS 352
           P+RKY VW+ G I  SLS
Sbjct: 981 PQRKYGVWVRGGITRSLS 1034
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|33942059|ref|NP_033384.2| delta isoform of regulatory
subunit B56, protein phosphatase 2A [Mus musculus]
         (594 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

00299                                                                 631   0.0  
01605                                                                 566   e-165
05988                                                                 230   1e-93
17656                                                                  29   4.3  
>00299
          Length = 1481

 Score =  631 bits (1628), Expect(2) = 0.0,   Method: Compositional matrix adjust.
 Identities = 308/395 (77%), Positives = 340/395 (86%)
 Frame = +1

Query: 23  SSSKDGGGENTDEAXXXXXXXXXXXXXXXXXXXXXXXQLSKIKYSGGPQIVKKERRQSSF 82
            S+K  G E+T+ A                        +SK+KY G P I KK++RQSS 
Sbjct: 112 GSAKSTGKESTENADSEAAKRKNPSQTGNADTHPPPTAISKLKYQGPPHI-KKDKRQSSS 288

Query: 83  PFNLNKNRELQKLPALKDSPTQEREELFIQKLRQCCVLFDFVSDPLSDLKCKEVKRAGLN 142
            FN++KNRELQKL  LKD+   EREELF+QKLRQC VLFDFV DPLSDLK KEVKRA LN
Sbjct: 289 RFNVSKNRELQKLALLKDATPAEREELFVQKLRQCIVLFDFVQDPLSDLKWKEVKRAALN 468

Query: 143 EMVEYITHSRDVVTEAIYPEAVTMFSVNLFRTLPPSSNPTGAEFDPEEDEPTLEAAWPHL 202
           EMVEY+T +R V+TEAIYPEA+TMF+VNLFRTLPPSSNP+GAEFDPEEDEPTLEAAWPHL
Sbjct: 469 EMVEYVTQNRGVITEAIYPEAITMFAVNLFRTLPPSSNPSGAEFDPEEDEPTLEAAWPHL 648

Query: 203 QLVYEFFLRFLESPDFQPNIAKKYIDQKFVLALLDLFDSEDPRERDFLKTILHRIYGKFL 262
           QLVYEFFLRFLESPDFQPN  K+YIDQKFVL LLDLFDSEDPRERDFLKTILHRIYGKFL
Sbjct: 649 QLVYEFFLRFLESPDFQPNTVKRYIDQKFVLQLLDLFDSEDPRERDFLKTILHRIYGKFL 828

Query: 263 GLRAYIRRQINHIFYRFIYETEHHNGIAELLEILGSIINGFALPLKEEHKVFLVRVLLPL 322
           GLRA+IR+ IN+IFY FIYETEHHNGIAELLEILGSIINGFALPLKEEHK+FL++VLLPL
Sbjct: 829 GLRAFIRKHINNIFYSFIYETEHHNGIAELLEILGSIINGFALPLKEEHKIFLLKVLLPL 1008

Query: 323 HKVKSLSVYHPQLAYCVVQFLEKESSLTEPVIVGLLKFWPKTHSPKEVMFLNELEEILDV 382
           HKVKSLSVYHPQLAYCVVQFLEK+ +LTE VI+GLLK+WPK HSPKEVMFLNELEEILDV
Sbjct: 1009HKVKSLSVYHPQLAYCVVQFLEKDPNLTEQVIMGLLKYWPKVHSPKEVMFLNELEEILDV 1188

Query: 383 IEPSEFSKVMEPLFRQLAKCVSSPHFQVAERALYY 417
           IEP+EF+KVM PLF+QLAKCVSSPHFQVAERALY+
Sbjct: 1189IEPAEFTKVMVPLFKQLAKCVSSPHFQVAERALYF 1293

 Score =  102 bits (255), Expect(2) = 0.0,   Method: Compositional matrix adjust.
 Identities = 46/57 (80%), Positives = 52/57 (91%)
 Frame = +3

Query: 417  YWNNEYIMSLISDNAARILPIMFPALYRNSKSHWNKTIHGLIYNALKLFMEMNQKLF 473
            +WNNEYI+SLISDN + I+P+MFPALY+ SK HWNKTIHGLIYNALKLFMEMNQKL 
Sbjct: 1290 FWNNEYILSLISDNVSSIMPLMFPALYK-SKEHWNKTIHGLIYNALKLFMEMNQKLL 1457
>01605
          Length = 971

 Score =  566 bits (1459), Expect(2) = e-165,   Method: Compositional matrix adjust.
 Identities = 271/310 (87%), Positives = 289/310 (93%)
 Frame = -3

Query: 105 EREELFIQKLRQCCVLFDFVSDPLSDLKCKEVKRAGLNEMVEYITHSRDVVTEAIYPEAV 164
           EREELF+QK+RQC VLFDFV DPLSDLK KEVKRA LNEMVE++T +R VVTE IYPEA+
Sbjct: 969 EREELFVQKIRQCSVLFDFVQDPLSDLKWKEVKRAALNEMVEFVTQNRGVVTEPIYPEAI 790

Query: 165 TMFSVNLFRTLPPSSNPTGAEFDPEEDEPTLEAAWPHLQLVYEFFLRFLESPDFQPNIAK 224
           TMFSVNLFRTLPPSSNP GAEFDPEEDEPTLEAAWPHLQL+YEFFLRFLESPDFQPN AK
Sbjct: 789 TMFSVNLFRTLPPSSNPNGAEFDPEEDEPTLEAAWPHLQLIYEFFLRFLESPDFQPNTAK 610

Query: 225 KYIDQKFVLALLDLFDSEDPRERDFLKTILHRIYGKFLGLRAYIRRQINHIFYRFIYETE 284
           +YIDQKFVL LLDLFDSEDPRERDFLKTILHRIYGKFLGLRA+IR+ IN+IFY FIYETE
Sbjct: 609 RYIDQKFVLQLLDLFDSEDPRERDFLKTILHRIYGKFLGLRAFIRKHINNIFYSFIYETE 430

Query: 285 HHNGIAELLEILGSIINGFALPLKEEHKVFLVRVLLPLHKVKSLSVYHPQLAYCVVQFLE 344
           HHNGIAELLEILGSIINGFALPLKEEHK FL++VLLPLHKVKSLSVYHPQLAYCVVQFLE
Sbjct: 429 HHNGIAELLEILGSIINGFALPLKEEHKTFLLKVLLPLHKVKSLSVYHPQLAYCVVQFLE 250

Query: 345 KESSLTEPVIVGLLKFWPKTHSPKEVMFLNELEEILDVIEPSEFSKVMEPLFRQLAKCVS 404
           K+ SLTE VI+GLLKFWPK HSPKEVMFLNELEEILDVIEP+EF+KVM PLF+QLAKCVS
Sbjct: 249 KDPSLTEQVIIGLLKFWPKVHSPKEVMFLNELEEILDVIEPAEFTKVMGPLFKQLAKCVS 70

Query: 405 SPHFQVAERA 414
           SPHFQ   R 
Sbjct: 69  SPHFQNDTRV 40

 Score = 35.8 bits (81), Expect(2) = e-165,   Method: Compositional matrix adjust.
 Identities = 15/16 (93%), Positives = 16/16 (100%)
 Frame = -1

Query: 452 KTIHGLIYNALKLFME 467
           +TIHGLIYNALKLFME
Sbjct: 56  RTIHGLIYNALKLFME 9
>05988
          Length = 569

 Score =  230 bits (587), Expect(2) = 1e-93,   Method: Compositional matrix adjust.
 Identities = 111/124 (89%), Positives = 119/124 (95%)
 Frame = +2

Query: 294 EILGSIINGFALPLKEEHKVFLVRVLLPLHKVKSLSVYHPQLAYCVVQFLEKESSLTEPV 353
           EILGSIINGFALPLKEEHK FL++VLLPLHKVKSLSVYHPQLAYCVVQFLEK+ SLTE V
Sbjct: 2   EILGSIINGFALPLKEEHKTFLLKVLLPLHKVKSLSVYHPQLAYCVVQFLEKDPSLTEQV 181

Query: 354 IVGLLKFWPKTHSPKEVMFLNELEEILDVIEPSEFSKVMEPLFRQLAKCVSSPHFQVAER 413
           I+GLLKFWPK HSPKEVMFLNELEEILDVIEP+EF+KVM PLF+QLAKCVSSPHFQVAER
Sbjct: 182 IIGLLKFWPKVHSPKEVMFLNELEEILDVIEPAEFTKVMGPLFKQLAKCVSSPHFQVAER 361

Query: 414 ALYY 417
           ALY+
Sbjct: 362 ALYF 373

 Score =  132 bits (331), Expect(2) = 1e-93,   Method: Composition-based stats.
 Identities = 56/67 (83%), Positives = 63/67 (94%)
 Frame = +1

Query: 417 YWNNEYIMSLISDNAARILPIMFPALYRNSKSHWNKTIHGLIYNALKLFMEMNQKLFDDC 476
           +WNNEYI+SLISDN + ++P+MFPALY+ SK HWNKTIHGLIYNALKLFMEMNQKLFDDC
Sbjct: 370 FWNNEYILSLISDNVSSVMPLMFPALYK-SKEHWNKTIHGLIYNALKLFMEMNQKLFDDC 546

Query: 477 TQQYKAE 483
           TQQYKAE
Sbjct: 547 TQQYKAE 567
>17656
          Length = 444

 Score = 29.3 bits (64), Expect = 4.3,   Method: Composition-based stats.
 Identities = 14/44 (31%), Positives = 24/44 (54%)
 Frame = -2

Query: 194 TLEAAWPHLQLVYEFFLRFLESPDFQPNIAKKYIDQKFVLALLD 237
           T + +W ++Q  ++ ++    SPD QP       D ++ LALLD
Sbjct: 386 TRDLSWDYIQARHQVYVDITGSPDVQP-------DWRYCLALLD 276
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|40556608|ref|NP_032328.2| heat shock protein 1, beta
[Mus musculus]
         (724 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

01628                                                                 706   0.0  
15623                                                                 309   1e-92
11278                                                                 223   3e-58
27487                                                                 160   1e-39
25874                                                                  80   4e-15
>01628
          Length = 2109

 Score =  706 bits (1822), Expect = 0.0,   Method: Compositional matrix adjust.
 Identities = 343/450 (76%), Positives = 388/450 (86%), Gaps = 1/450 (0%)
 Frame = -3

Query: 276  YIDQEELNKTKPIWTRNPDDITQEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFI 335
            Y ++EELNKTKP+WTRNPDDIT EEY EFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFI
Sbjct: 1969 YTEEEELNKTKPLWTRNPDDITAEEYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFI 1790

Query: 336  PRRAPFDLFENKKKKNNIKLYVRRVFIMDSCDELIPEYLNFIRGVVDSEDLPLNISREML 395
            P+RAPFD+FENKKKKNNIKLYVRRVFIMD+C+++IPEYLNF++GVVDSEDLPLNISREML
Sbjct: 1789 PKRAPFDMFENKKKKNNIKLYVRRVFIMDNCEDIIPEYLNFVKGVVDSEDLPLNISREML 1610

Query: 396  QQSKILKVIRKNIVKKCLELFSELAEDKENYKKFYEAFSKNLKLGIHEDSTNRRRLSELL 455
            QQSKILKVIRKN+VKKC+EL  +LAEDK+NY KFYE F+KNLKLGIHEDSTNR+++S+ L
Sbjct: 1609 QQSKILKVIRKNLVKKCMELIDDLAEDKDNYNKFYEQFAKNLKLGIHEDSTNRKKISDFL 1430

Query: 456  RYHTSQSGDEMTSLSEYVSRMKETQKSIYYITGESKEQVANSAFVERVRKRGFEVVYMTE 515
            RYH+SQS DEM +  EYVSRMK+ QK IYYITGE++E V NSAFVERV+KRGFEV+YM +
Sbjct: 1429 RYHSSQSADEMVTFKEYVSRMKDNQKDIYYITGETREAVQNSAFVERVKKRGFEVLYMVD 1250

Query: 516  PIDEYCVQQLKEFDGKSLVSVTXXXXXXXXXXXXXXXXXXXXXXXXNLCKLMKEILDKKV 575
            PIDEYCVQQLKE+DGK+LV VT                         LCK MKEILDKKV
Sbjct: 1249 PIDEYCVQQLKEYDGKNLVCVTKEGLELPEDEAEKKKFEEAKAEFEGLCKAMKEILDKKV 1070

Query: 576  EKVTISNRLVSSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMMAKKHLEINPDHPIV 635
            EKVT+S RLVSSPCCIVTS YGW+ANMERIMKAQALRD STMGYM AKKH EINPDHPIV
Sbjct: 1069 EKVTVSQRLVSSPCCIVTSQYGWSANMERIMKAQALRDTSTMGYMAAKKHFEINPDHPIV 890

Query: 636  ETLRQKAEADKNDKAVKDLVVLLFETALLSSGFSLEDPQTHSNRIYRMIKLGLGIDEDEV 695
            +TL+ K +ADKNDK+VKDL +LLFETALLSSGF+LEDP +H+NRI+RM+KLGLGIDED+ 
Sbjct: 889  KTLKVKCDADKNDKSVKDLCMLLFETALLSSGFTLEDPTSHANRIHRMVKLGLGIDEDDS 710

Query: 696  TAEEPSAAVPDEIPPLEGDE-DASRMEEVD 724
            T E   A   D++PPLEGDE DASRMEEVD
Sbjct: 709  TPEAAEAPA-DDMPPLEGDEDDASRMEEVD 623
>15623
          Length = 2811

 Score =  309 bits (792), Expect(2) = 1e-92,   Method: Compositional matrix adjust.
 Identities = 145/185 (78%), Positives = 168/185 (90%)
 Frame = -1

Query: 35  NKEIFLRELISNASDALDKIRYESLTDPSKLDSGKELKIDIIPNPQERTLTLVDTGIGMT 94
            +EIFLRELISN+SDALDKIRYESLTDPSKLD+GK+L I I+P+ + +TLT+ D+GIGMT
Sbjct: 588 QQEIFLRELISNSSDALDKIRYESLTDPSKLDAGKDLHIRIVPDKERKTLTIEDSGIGMT 409

Query: 95  KADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVVVITKHNDDEQ 154
           KADL+NNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVA++VVV +K+NDDEQ
Sbjct: 408 KADLVNNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVADRVVVESKNNDDEQ 229

Query: 155 YAWESSAGGSFTVRADHGEPIGRGTKVILHLKEDQTEYLEERRVKEVVKKHSQFIGYPIT 214
           Y WESSAGGSFT+ A  G P+GRGT++ L +KEDQ EYLEERR+KEV+KKHSQFIGYPI 
Sbjct: 228 YTWESSAGGSFTIAAPTGTPMGRGTRITLFMKEDQQEYLEERRIKEVIKKHSQFIGYPIK 49

Query: 215 LYLEK 219
           L +EK
Sbjct: 48  LLVEK 34

 Score = 49.7 bits (117), Expect(2) = 1e-92,   Method: Compositional matrix adjust.
 Identities = 23/25 (92%), Positives = 24/25 (96%)
 Frame = -2

Query: 14  TFAFQAEIAQLMSLIINTFYSNKEI 38
           TFAFQAEIAQLMSLIINTFYSNK+ 
Sbjct: 650 TFAFQAEIAQLMSLIINTFYSNKKF 576
>11278
          Length = 988

 Score =  223 bits (567), Expect = 3e-58,   Method: Compositional matrix adjust.
 Identities = 115/209 (55%), Positives = 147/209 (70%), Gaps = 4/209 (1%)
 Frame = +1

Query: 15  FAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGKELKID 74
           FAFQAE+ ++M LIIN+ Y NKEIFLRELISNASDALDKIR+ SLT+   L +  EL I 
Sbjct: 265 FAFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRFMSLTNKDVLHATDELSIK 444

Query: 75  IIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADI---SMIGQFGV 131
           I  + +   L + DTGIGMT  DL+ NLGTIAKSGT  F+  +   +      +IGQFGV
Sbjct: 445 IKADTENHVLHVTDTGIGMTYNDLVKNLGTIAKSGTSDFLAKMGEASPTELNDLIGQFGV 624

Query: 132 GFYSAYLVAEKVVVITKHNDDEQYAWESSAGGSFTVRAD-HGEPIGRGTKVILHLKEDQT 190
           GFYS++LVA++VVV +KHNDDEQY WES A  SF+V  D  G  +GRGT + LHLKE+  
Sbjct: 625 GFYSSFLVADRVVVTSKHNDDEQYVWESDA-ESFSVAKDPRGNTLGRGTTISLHLKEEAH 801

Query: 191 EYLEERRVKEVVKKHSQFIGYPITLYLEK 219
           ++LE   +  +VKK+SQFI + I ++  K
Sbjct: 802 DFLEAGTLTSLVKKYSQFINFNIYMWSSK 888
>27487
          Length = 377

 Score =  160 bits (406), Expect = 1e-39,   Method: Compositional matrix adjust.
 Identities = 81/124 (65%), Positives = 109/124 (87%)
 Frame = -3

Query: 395 LQQSKILKVIRKNIVKKCLELFSELAEDKENYKKFYEAFSKNLKLGIHEDSTNRRRLSEL 454
           LQQ+KILKVI+KNIVKKCLE+F+E+AE+ ++YKKFYE FSKNLKLGIHED+TNR +L +L
Sbjct: 372 LQQNKILKVIKKNIVKKCLEMFAEIAENNDDYKKFYEQFSKNLKLGIHEDTTNRTKLVDL 193

Query: 455 LRYHTSQSGDEMTSLSEYVSRMKETQKSIYYITGESKEQVANSAFVERVRKRGFEVVYMT 514
           +R+HTS+SG++  SL EY++RMKE QK I+YITGES+  V  S F+E++RK+G+EV+Y+ 
Sbjct: 192 MRFHTSKSGEDQISLKEYIARMKEGQKDIFYITGESRAAVQASPFIEQLRKKGYEVLYLV 13

Query: 515 EPID 518
           +PID
Sbjct: 12  DPID 1
>25874
          Length = 476

 Score = 79.7 bits (195), Expect = 4e-15,   Method: Compositional matrix adjust.
 Identities = 39/91 (42%), Positives = 57/91 (62%)
 Frame = +1

Query: 125 MIGQFGVGFYSAYLVAEKVVVITKHNDDEQYAWESSAGGSFTVRADHGEPIGRGTKVILH 184
           +IGQFGVGFYS ++V ++V V TK +     A + S+ GS        E + RGTK+++H
Sbjct: 1   LIGQFGVGFYSTFMVGDRVDVFTKSHQPGSPALKWSSDGSGAYEVSEAEGVQRGTKIVVH 180

Query: 185 LKEDQTEYLEERRVKEVVKKHSQFIGYPITL 215
           LK D  ++ +E  +  VVKK+S F+G PI L
Sbjct: 181 LKGDSYDFAKEEIITGVVKKYSNFVGVPIYL 273
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|5457150|gb|AAD43813.1|AF164349_1 Na,K-ATPase alpha-4
subunit [Mus musculus]
         (740 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

00499                                                                 974   0.0  
14773                                                                 357   1e-98
06342                                                                 256   3e-68
08160                                                                 199   5e-51
12151                                                                  85   1e-24
36566                                                                 108   6e-24
03937                                                                 103   3e-22
33697                                                                  74   9e-21
17925                                                                  89   8e-18
29829                                                                  74   2e-13
28890                                                                  72   8e-13
13525                                                                  68   2e-11
04985                                                                  57   4e-08
14321                                                                  48   2e-05
07486                                                                  39   0.006
10129                                                                  31   2.0  
>00499
          Length = 4026

 Score =  974 bits (2519), Expect = 0.0,   Method: Compositional matrix adjust.
 Identities = 473/676 (69%), Positives = 550/676 (81%), Gaps = 2/676 (0%)
 Frame = +2

Query: 67  KRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHLWFDKTVYEADTSEEQTT 126
           KRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAH+WFD  + EADTS++Q+ 
Sbjct: 44  KRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDGRIVEADTSDDQSN 223

Query: 127 GKTFPKSSDTWFYLARIAGLCNRADFKPHQESVPIAKRATTGDASESALLKFIEQSYSPV 186
             T+ +S  TW  L+R+A LCNRA+FK +Q++VPI KR   GDASESALLK +E S   V
Sbjct: 224 A-TYSRSDPTWMALSRVAMLCNRAEFKGNQDNVPILKRECNGDASESALLKCVELSIGHV 400

Query: 187 SEMRQKNPKVAEIPFNSTNKYQMSIHLLED-NSEAHVLLMKGAPERIFDFCSSFLLNGQE 245
           +E R++N K+ EIPFNS+NKYQ+SIH  ED +   ++L+MKGAPERI D CS+ LLNG+E
Sbjct: 401 TEYRRRNEKIVEIPFNSSNKYQVSIHETEDPDDPRYLLVMKGAPERIMDRCSTILLNGKE 580

Query: 246 YPMDEEMKTDFQNAYIELGGLGERVLGFCFLNLP-SNFSKGFQFNTDELNFPMENLCFAG 304
            P+D+  +  F  AY+ELGGLGERVLGFC   LP   F  G++F+ +  NFP+  L F G
Sbjct: 581 QPLDDNFREAFNAAYLELGGLGERVLGFCDYFLPVDQFPPGYEFDPEGPNFPITGLRFVG 760

Query: 305 LISMIDPPRTAVPDAVSKCRSAGIKVIMVTGDHPITAKAIAKSVGIISEGNDTAEDIAAR 364
           L++MIDPPR AVPDAV KCRSAGIKVIMVTGDHPITAKAIA+ VGIISEG+ T EDIA+ 
Sbjct: 761 LMAMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIARGVGIISEGSKTVEDIASE 940

Query: 365 LNIPISQVNNKSVKAIVVHGSELKDMESQQLDDILKSYKEIVFARTSPQQKLIIVEGCQR 424
             IP+ +V+ +  KA V+HG +L+DM   Q+D+IL+++ EIVFARTSPQQKLIIVEGCQR
Sbjct: 941 RGIPVEEVDPREAKAAVIHGGDLRDMTPAQIDEILRNHSEIVFARTSPQQKLIIVEGCQR 1120

Query: 425 LGAIVAVTGDGVNDSPALKKADIGIAMGITGSDVSKQAADMILLDDNFASIVTGVEEGRL 484
            G IVAVTGDGVNDSPALKKADIG+AMGI GSDVSKQAADMILLDDNFASIVTGVEEGRL
Sbjct: 1121QGQIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILLDDNFASIVTGVEEGRL 1300

Query: 485 IFDNLKKSIAYTLTSNIPEITXXXXXXXXXXXXXXGTITILCIDLGTDMVPAISLAYESP 544
           IFDNLKKSIAYTLTSNIPEI+              GTITILCIDLGTDMVPAISLAYE  
Sbjct: 1301IFDNLKKSIAYTLTSNIPEISPFLLFILADIPLPLGTITILCIDLGTDMVPAISLAYEKA 1480

Query: 545 ESDIMKRLPRNPKTDNLVNNRLIGMAYGQIGMIQALAGFFTYFVILAENGFKPLDLLGIR 604
           E+DIMKR PR+P  D LVN RLI MAYGQIGMIQA AGFFTYFVI+ ENGF    LLGIR
Sbjct: 1481ENDIMKRQPRDPVKDKLVNERLISMAYGQIGMIQASAGFFTYFVIMGENGFWYDRLLGIR 1660

Query: 605 LYWDDTQLNDLEDSYGQQWTYEQRKVVEFTCQTAFFISIVIVQWADLIICKTRRNSLFKQ 664
           + WD   +NDLEDSYGQ+WTY QRK +E+TC TAFF+SIVIVQWAD+IICKTRR SLF+Q
Sbjct: 1661MEWDSRGVNDLEDSYGQEWTYSQRKKLEYTCHTAFFVSIVIVQWADIIICKTRRLSLFQQ 1840

Query: 665 GMKNKILIFGLLEETVLAAFLSYVPGMDVSLRMYPLKINWWFCALPYSVLIFVYDEIRKL 724
           GMKNK LIFG+  ET LAAFL Y PG+D  LRMYPL++ WWF A+P+S+ IF+YDE RKL
Sbjct: 1841GMKNKHLIFGIFFETALAAFLCYCPGLDKGLRMYPLRLTWWFTAVPFSLTIFIYDECRKL 2020

Query: 725 IIRRRPGGWLEKETYY 740
           I+RR PGG++E+ETYY
Sbjct: 2021ILRRNPGGFVERETYY 2068
>14773
          Length = 794

 Score =  357 bits (915), Expect = 1e-98,   Method: Compositional matrix adjust.
 Identities = 176/265 (66%), Positives = 201/265 (75%)
 Frame = +2

Query: 456 SDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITXXXXXXXXXX 515
           SDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEI+          
Sbjct: 2   SDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEISPFLVYILFGT 181

Query: 516 XXXXGTITILCIDLGTDMVPAISLAYESPESDIMKRLPRNPKTDNLVNNRLIGMAYGQIG 575
               G ITIL IDLGTDMVPAISLAYE  ESDIMKR PR   +D LVN RLI M+YGQIG
Sbjct: 182 PLPLGVITILFIDLGTDMVPAISLAYEMAESDIMKRPPRT-ISDRLVNERLIAMSYGQIG 358

Query: 576 MIQALAGFFTYFVILAENGFKPLDLLGIRLYWDDTQLNDLEDSYGQQWTYEQRKVVEFTC 635
           M+QALAGF+ + ++  ++GF   DL GIR +WD   +NDLEDSYGQ WT  QR  VE + 
Sbjct: 359 MMQALAGFYAWILVFGQSGFMVRDLPGIRSFWDSANINDLEDSYGQNWTKAQRMDVELSG 538

Query: 636 QTAFFISIVIVQWADLIICKTRRNSLFKQGMKNKILIFGLLEETVLAAFLSYVPGMDVSL 695
            T FFI+IV+VQW+D+IICKTRR S+F QGM N +L FG+  ET LA  LSY PG+DV+L
Sbjct: 539 YTVFFITIVLVQWSDIIICKTRRLSVFHQGMSNHVLTFGIFFETSLAVLLSYTPGVDVAL 718

Query: 696 RMYPLKINWWFCALPYSVLIFVYDE 720
           R  PL+  WW  A+P+ VLIFVYDE
Sbjct: 719 RTRPLRFEWWLAAIPFQVLIFVYDE 793
>06342
          Length = 2428

 Score =  256 bits (653), Expect = 3e-68,   Method: Compositional matrix adjust.
 Identities = 183/605 (30%), Positives = 296/605 (48%), Gaps = 48/605 (7%)
 Frame = +2

Query: 1   PIATEIEHFIHLITAVAVFLGVSFFWLSI------ILGYTWLDAVIFLIGIIVANV---- 50
           P+  +++ F + ++ V   + ++ + ++I        G +W+   I+   I VA      
Sbjct: 314 PLQQKLDEFSNQLSKVITIICIAVWAINIGHFNDPAHGGSWIKGAIYYFKIAVALAVAAI 493

Query: 51  PEGXXXXXXXXXXXXXKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHLW 110
           PEG             +RMA+KN +V++L +VETLG TS ICSDKTGTLT N+M+V  L+
Sbjct: 494 PEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCKLF 673

Query: 111 FDKTV--YEADTSEEQTTGKTFP------------KSSD--TWFYLARIAGLCNRADFKP 154
               +   +  T++ + TG T+             K+SD      L  I G+CN +    
Sbjct: 674 IFSQIDTNQIKTTQFEVTGSTYAPDGELYQNGKKVKASDYPGLEELCTICGMCNDSSVDY 853

Query: 155 HQESVPIAKRATTGDASESALLKFIEQSYSPVSEMRQKNPKVAEIPFN------------ 202
           ++      K    G+A+E+AL    E+     ++    N +      N            
Sbjct: 854 NEAKTQYEK---VGEATETALTVLAEKLNFYNTDKSSLNKREMGTVCNHVIQDMWRKEFT 1024

Query: 203 ---STNKYQMSIHLLEDNSE----AHVLLMKGAPERIFDFCSSFLLNGQEYPMDEEMKTD 255
              S ++  MS+  + +          +  KGAPE + D C+   +   + PM   +K +
Sbjct: 1025LEFSRDRKSMSVFCVPNKPTRVPGGARMFAKGAPEGLLDRCTHVRIGNNKVPMSPAIKNE 1204

Query: 256 FQNAYIELGGLGERVLGFCFLNLPSNFSKGFQFNTDELNFPME---NLCFAGLISMIDPP 312
                 ++ G G   L    L    N  +    + ++    +E   N+ F G++ M+DPP
Sbjct: 1205IMK-LTKIYGTGRDTLRCLALATIDNPPRREDMDLEDSRKFIEYETNMTFVGVVGMLDPP 1381

Query: 313 RTAVPDAVSKCRSAGIKVIMVTGDHPITAKAIAKSVGIISEGNDTAEDIAARLNIPISQV 372
           R  V  ++  CR+AGI+VI++TGD+  TA+AI + +G+ SE  +T               
Sbjct: 1382REEVMASIKNCRAAGIRVIVITGDNKATAEAICRRIGVFSESENT--------------- 1516

Query: 373 NNKSVKAIVVHGSELKDMESQQLDDILKSYKEIVFARTSPQQKLIIVEGCQRLGAIVAVT 432
                + +   G E  ++  +  D      +  +FAR  P  K  IVE  Q  G I A+T
Sbjct: 1517-----EGLAYTGREFDELPPE--DQRAAVMRARLFARVEPAHKSKIVEYLQAEGEISAMT 1675

Query: 433 GDGVNDSPALKKADIGIAMGITGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKS 492
           GDGVND+PALKKA+IGIAMG +G+ V+K A++M+L DDNF++IV  VEEGR I++N+K+ 
Sbjct: 1676GDGVNDAPALKKAEIGIAMG-SGTAVAKSASEMVLADDNFSTIVAAVEEGRAIYNNMKQF 1852

Query: 493 IAYTLTSNIPEITXXXXXXXXXXXXXXGTITILCIDLGTDMVPAISLAYESPESDIMKRL 552
           I Y ++SNI E+                 + +L ++L TD  PA +L +  P+ DIM++ 
Sbjct: 1853IRYLISSNIGEVVCIFLTAALGIPEALIPVQLLWVNLVTDGFPATALGFNPPDLDIMQKP 2032

Query: 553 PRNPK 557
           PRNP+
Sbjct: 2033PRNPR 2047
>08160
          Length = 459

 Score =  199 bits (505), Expect = 5e-51,   Method: Compositional matrix adjust.
 Identities = 94/139 (67%), Positives = 113/139 (81%)
 Frame = +2

Query: 67  KRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHLWFDKTVYEADTSEEQTT 126
           KRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAH+WFD  + EADTS++Q+ 
Sbjct: 44  KRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDGRIVEADTSDDQSN 223

Query: 127 GKTFPKSSDTWFYLARIAGLCNRADFKPHQESVPIAKRATTGDASESALLKFIEQSYSPV 186
             T+ ++  TW  LAR+  LCNRA+FK +Q++VPI KR   GDASESALLK +E S   V
Sbjct: 224 A-TYSRTDVTWMALARVGMLCNRAEFKGNQDNVPILKRECNGDASESALLKAVELSIGQV 400

Query: 187 SEMRQKNPKVAEIPFNSTN 205
           +E R++N K+ EIPFNS+N
Sbjct: 401 TEYRRRNKKIVEIPFNSSN 457
>12151
          Length = 880

 Score = 85.1 bits (209), Expect(2) = 1e-24,   Method: Compositional matrix adjust.
 Identities = 50/141 (35%), Positives = 81/141 (57%), Gaps = 3/141 (2%)
 Frame = +3

Query: 443 KKADIGIAMGITGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIP 502
           +KAD+G AMGI+G+DV+K+A+D+IL DDNF SIV  V  GR ++D++ K + + LT N+ 
Sbjct: 288 QKADVGFAMGISGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSIAKFLQFQLTVNVV 467

Query: 503 EITXXXXXXXXXXXXXXGTITILCIDLGTDMVPAISLAYESPESDIMKRLP---RNPKTD 559
            +                 I +L ++L  D + +++LA E P S+++KR P     P   
Sbjct: 468 AVFVAFVGACSIGDSPLKAIQMLWVNLIMDTLASLALATELPSSELLKRRPYGRTKPLIS 647

Query: 560 NLVNNRLIGMAYGQIGMIQAL 580
             +   ++G A+ QI +I  L
Sbjct: 648 KTMWKNILGHAFYQILVILLL 710

 Score = 47.4 bits (111), Expect(2) = 1e-24,   Method: Compositional matrix adjust.
 Identities = 39/122 (31%), Positives = 58/122 (47%), Gaps = 13/122 (10%)
 Frame = +1

Query: 336 DHPITAKAIAKSVGIISEGNDTAEDIAARLNIPISQVNNKSVKAIVVHGSE----LKDME 391
           D+  TA++IA   GII  G+D                       +V+ G E    ++D E
Sbjct: 1   DNVNTARSIASKCGIIQPGDD----------------------GLVLEGKEFNQLIRDAE 114

Query: 392 SQ----QLDDILKSYKEIVFARTSPQQKLIIVE-----GCQRLGAIVAVTGDGVNDSPAL 442
            +    ++D++  + +  V AR+SPQ K I+V+            +VAVTGDG ND PAL
Sbjct: 115 GEISQEKVDEVWPNLR--VLARSSPQDKYILVKHIIDSKVSTSREVVAVTGDGTNDGPAL 288

Query: 443 KK 444
           KK
Sbjct: 289 KK 294
>36566
          Length = 589

 Score =  108 bits (271), Expect = 6e-24,   Method: Compositional matrix adjust.
 Identities = 58/146 (39%), Positives = 94/146 (64%)
 Frame = +3

Query: 422 CQRLGAIVAVTGDGVNDSPALKKADIGIAMGITGSDVSKQAADMILLDDNFASIVTGVEE 481
            Q+ G +V +TGDGVND+ ALK A+IGI+MG++G+DVSK+A+DMIL+DD+F +I+  +EE
Sbjct: 108 LQQNGLVVGMTGDGVNDAVALKSAEIGISMGVSGTDVSKEASDMILVDDDFTTILNAIEE 287

Query: 482 GRLIFDNLKKSIAYTLTSNIPEITXXXXXXXXXXXXXXGTITILCIDLGTDMVPAISLAY 541
           G+ IF N++  + + L+++I  ++                + IL I++  D  PA SL  
Sbjct: 288 GKGIFYNIRNFVRFQLSTSIAALSLIAVSTLLRLPNPLNAMQILWINIIMDGPPAQSLGV 467

Query: 542 ESPESDIMKRLPRNPKTDNLVNNRLI 567
           E  + D++K+ PR+   D ++  RLI
Sbjct: 468 EPVDHDVIKQPPRH-VGDPIITRRLI 542
>03937
          Length = 1558

 Score =  103 bits (257), Expect = 3e-22,   Method: Compositional matrix adjust.
 Identities = 46/78 (58%), Positives = 58/78 (74%)
 Frame = -2

Query: 663  KQGMKNKILIFGLLEETVLAAFLSYVPGMDVSLRMYPLKINWWFCALPYSVLIFVYDEIR 722
            +QGMKNK LIF          FL Y PG+D  LRMYPL++ WWF A+P+S+ IF+YDE R
Sbjct: 1557 QQGMKNKHLIFDXFF*DGAGRFLCYCPGLDKGLRMYPLRLTWWFTAVPFSLTIFIYDECR 1378

Query: 723  KLIIRRRPGGWLEKETYY 740
            KLI+RR PGG++E+ETYY
Sbjct: 1377 KLILRRXPGGFVERETYY 1324
>33697
          Length = 310

 Score = 74.3 bits (181), Expect(2) = 9e-21,   Method: Composition-based stats.
 Identities = 32/37 (86%), Positives = 34/37 (91%)
 Frame = -2

Query: 307 SMIDPPRTAVPDAVSKCRSAGIKVIMVTGDHPITAKA 343
           SMIDPPR AVPDAV KCRSAGIKVIMVTGDHPIT++ 
Sbjct: 204 SMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITSQG 94

 Score = 44.3 bits (103), Expect(2) = 9e-21,   Method: Composition-based stats.
 Identities = 21/33 (63%), Positives = 26/33 (78%)
 Frame = -3

Query: 341 AKAIAKSVGIISEGNDTAEDIAARLNIPISQVN 373
           AKAIAK VGIISEG+ T EDI+A   IP+ +V+
Sbjct: 101 AKAIAKGVGIISEGSRTVEDISAERGIPVEEVD 3
>17925
          Length = 510

 Score = 88.6 bits (218), Expect = 8e-18,   Method: Compositional matrix adjust.
 Identities = 40/60 (66%), Positives = 52/60 (86%)
 Frame = +3

Query: 375 KSVKAIVVHGSELKDMESQQLDDILKSYKEIVFARTSPQQKLIIVEGCQRLGAIVAVTGD 434
           +  +AIV+HG +LK+M+++ +DDIL ++ EIVFARTSPQQKLIIVEGCQR G IVAVTG+
Sbjct: 315 REAEAIVIHGGDLKNMDAKDIDDILHNFVEIVFARTSPQQKLIIVEGCQRNGQIVAVTGE 494
>29829
          Length = 465

 Score = 74.3 bits (181), Expect = 2e-13,   Method: Compositional matrix adjust.
 Identities = 52/158 (32%), Positives = 85/158 (53%), Gaps = 1/158 (0%)
 Frame = -3

Query: 447 IGIAMGITGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITX 506
           +G AMGI+G+DV+K+A+D+IL DDNF SIV  V  GR ++D++ K + + LT N+  +  
Sbjct: 460 LGFAMGISGTDVAKEASDIILTDDNFTSIVKAVXWGRNVYDSIAKFLQFQLTVNVVAVFV 281

Query: 507 XXXXXXXXXXXXXGTITILCIDLGTDMVPAISLAYESPESDIMKRLPRNPKTDNLVNNRL 566
                          I +L ++L  D + +++LA E P ++++KR P   +T  L++   
Sbjct: 280 AFVGACSIGDSPLEAIQMLWVNLIMDTLASLALATELPSNELLKRKPYG-RTKPLISKT- 107

Query: 567 IGMAYGQIGMIQALAGFFTY-FVILAENGFKPLDLLGI 603
                    M + +AG   Y  +I+    FK  DL GI
Sbjct: 106 ---------MFKNIAGHSVYQIIIILVILFKGADLFGI 20
>28890
          Length = 552

 Score = 72.0 bits (175), Expect = 8e-13,   Method: Compositional matrix adjust.
 Identities = 33/42 (78%), Positives = 36/42 (85%)
 Frame = -3

Query: 1   PIATEIEHFIHLITAVAVFLGVSFFWLSIILGYTWLDAVIFL 42
           PIA EI HFIH+IT VAVFLGVSFF ++ ILGY WLDAVIFL
Sbjct: 127 PIAKEIAHFIHIITGVAVFLGVSFFVIAFILGYFWLDAVIFL 2
>13525
          Length = 645

 Score = 67.8 bits (164), Expect = 2e-11,   Method: Composition-based stats.
 Identities = 31/31 (100%), Positives = 31/31 (100%)
 Frame = +2

Query: 67 KRMARKNCLVKNLEAVETLGSTSTICSDKTG 97
          KRMARKNCLVKNLEAVETLGSTSTICSDKTG
Sbjct: 11 KRMARKNCLVKNLEAVETLGSTSTICSDKTG 103
>04985
          Length = 1671

 Score = 56.6 bits (135), Expect = 4e-08,   Method: Compositional matrix adjust.
 Identities = 30/78 (38%), Positives = 41/78 (52%)
 Frame = -1

Query: 406  VFARTSPQQKLIIVEGCQRLGAIVAVTGDGVNDSPALKKADIGIAMGITGSDVSKQAADM 465
            VFAR +P QK  ++E  Q    IV + GDG ND  ALK A  GI++    + V+      
Sbjct: 1608 VFARMAPDQKCALIENLQSYDYIVGMCGDGANDCEALKAAHAGISLSEAEASVAAPFTSR 1429

Query: 466  ILLDDNFASIVTGVEEGR 483
            I   +N   +VT + EGR
Sbjct: 1428 I---NNIECVVTAMREGR 1384
>14321
          Length = 568

 Score = 47.8 bits (112), Expect = 2e-05,   Method: Composition-based stats.
 Identities = 21/46 (45%), Positives = 31/46 (67%)
 Frame = +2

Query: 406 VFARTSPQQKLIIVEGCQRLGAIVAVTGDGVNDSPALKKADIGIAM 451
           VFAR +P+QK +I+   +  G +  + GDG ND  ALK AD+G+A+
Sbjct: 266 VFARVAPKQKELIITVLKAQGFVTLMCGDGTNDVGALKHADVGVAL 403
>07486
          Length = 763

 Score = 39.3 bits (90), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 22/62 (35%), Positives = 39/62 (62%)
 Frame = -1

Query: 441 ALKKADIGIAMGITGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSN 500
           AL +AD+GIA+G TG+DV+ +AAD++L+  +   +   ++  R      K+  A+T T +
Sbjct: 742 ALAQADVGIAIG-TGTDVAVEAADIVLMKSDLVDVYAAIKLSR------KQCGAFTSTLS 584

Query: 501 IP 502
           +P
Sbjct: 583 LP 578
>10129
          Length = 988

 Score = 30.8 bits (68), Expect = 2.0,   Method: Compositional matrix adjust.
 Identities = 17/60 (28%), Positives = 35/60 (58%), Gaps = 1/60 (1%)
 Frame = +3

Query: 354 GNDTAEDIAARLNIPISQVNNKSVKAIVVHGSELK-DMESQQLDDILKSYKEIVFARTSP 412
            +DT  +   +  I  S  N + +K ++    +L  D++++++DD++ + K +VFART P
Sbjct: 726 SDDTDSEPFCQPKIFFSPQNFEQIKPLIADRRQLX*DLQTKKIDDLIVA*KGVVFARTFP 905
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6671509|ref|NP_031419.1| actin, beta [Mus musculus]
         (375 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

04742                                                                 760   0.0  
39562                                                                 612   e-175
02757                                                                 299   e-123
12322                                                                 239   2e-63
00608                                                                 199   1e-51
01436                                                                 176   2e-44
11487                                                                  96   7e-43
19721                                                                 100   7e-33
36954                                                                 123   1e-28
32273                                                                 123   1e-28
18926                                                                 111   3e-25
13361                                                                  93   2e-19
17032                                                                  35   0.044
06132                                                                  30   1.5  
06084                                                                  28   7.5  
>04742
          Length = 2111

 Score =  760 bits (1963), Expect = 0.0,   Method: Compositional matrix adjust.
 Identities = 360/374 (96%), Positives = 368/374 (98%)
 Frame = +2

Query: 2   DDDIAALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSK 61
           D+D+AALV+DNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSK
Sbjct: 98  DEDVAALVIDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSK 277

Query: 62  RGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQ 121
           RGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQ
Sbjct: 278 RGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQ 457

Query: 122 IMFETFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHTVPIYEGYALPHAILRLDLA 181
           IMFETFN+PAMYVAIQAVLSLYASGRTTGIV+DSGDGV HTVPIYEGYALPHAI RLDLA
Sbjct: 458 IMFETFNSPAMYVAIQAVLSLYASGRTTGIVLDSGDGVXHTVPIYEGYALPHAISRLDLA 637

Query: 182 GRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYE 241
           GRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEM TAASSSSLEKSYE
Sbjct: 638 GRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMQTAASSSSLEKSYE 817

Query: 242 LPDGQVITIGNERFRCPEALFQPSFLGMESCGIHETTFNSIMKCDVDIRKDLYANTVLSG 301
           LPDGQVITIGNERFRCPEA+FQPSFLGMES G HETT+NSIMKCDVDIRKDLYANTVLSG
Sbjct: 818 LPDGQVITIGNERFRCPEAMFQPSFLGMESAGXHETTYNSIMKCDVDIRKDLYANTVLSG 997

Query: 302 GTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQE 361
           G+TMYPGIADRMQKEITALAP TMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQE
Sbjct: 998 GSTMYPGIADRMQKEITALAPPTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQE 1177

Query: 362 YDESGPSIVHRKCF 375
           YDESGPSIVHRKCF
Sbjct: 1178YDESGPSIVHRKCF 1219
>39562
          Length = 1438

 Score =  612 bits (1577), Expect = e-175,   Method: Compositional matrix adjust.
 Identities = 291/301 (96%), Positives = 297/301 (98%)
 Frame = -2

Query: 75   IVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYV 134
            IVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFN+PAMYV
Sbjct: 1437 IVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNSPAMYV 1258

Query: 135  AIQAVLSLYASGRTTGIVMDSGDGVTHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILT 194
            AIQAVLSLYASGRTTGIV+DSGDGVTHTVPIYEGYALPHAI+RLDLAGRDLTDYLMKILT
Sbjct: 1257 AIQAVLSLYASGRTTGIVLDSGDGVTHTVPIYEGYALPHAIMRLDLAGRDLTDYLMKILT 1078

Query: 195  ERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELPDGQVITIGNER 254
            ERGYSFTTTAEREIVRDIKEKL YVALDFEQEM TAASSSSLEKSYELPDGQVITIGNER
Sbjct: 1077 ERGYSFTTTAEREIVRDIKEKLDYVALDFEQEMLTAASSSSLEKSYELPDGQVITIGNER 898

Query: 255  FRCPEALFQPSFLGMESCGIHETTFNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQ 314
            FRCPEA+FQPSFLGMES GIHETT+NSIMKCDVDIRKDLYANTVLSGG+TMYPGIADRMQ
Sbjct: 897  FRCPEAMFQPSFLGMESAGIHETTYNSIMKCDVDIRKDLYANTVLSGGSTMYPGIADRMQ 718

Query: 315  KEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKC 374
            KEITALAP TMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKC
Sbjct: 717  KEITALAPPTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKC 538

Query: 375  F 375
            F
Sbjct: 537  F 535
>02757
          Length = 1094

 Score =  299 bits (765), Expect(3) = e-123,   Method: Compositional matrix adjust.
 Identities = 145/151 (96%), Positives = 148/151 (98%)
 Frame = -2

Query: 172 PHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAA 231
           P AILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIV DIKEKLCYVALDFEQEMATAA
Sbjct: 997 PTAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVXDIKEKLCYVALDFEQEMATAA 818

Query: 232 SSSSLEKSYELPDGQVITIGNERFRCPEALFQPSFLGMESCGIHETTFNSIMKCDVDIRK 291
           SSSSLEKSYELPDGQVITIGNERFRCPE+LFQPSFLGMES GIHETT+NSIMKCDVDIRK
Sbjct: 817 SSSSLEKSYELPDGQVITIGNERFRCPESLFQPSFLGMESAGIHETTYNSIMKCDVDIRK 638

Query: 292 DLYANTVLSGGTTMYPGIADRMQKEITALAP 322
           DLYANTVLSGGTTM+PGIADRMQKEITALAP
Sbjct: 637 DLYANTVLSGGTTMFPGIADRMQKEITALAP 545

 Score =  111 bits (278), Expect(3) = e-123,   Method: Compositional matrix adjust.
 Identities = 52/53 (98%), Positives = 52/53 (98%)
 Frame = -3

Query: 323 STMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF 375
           STMKIK IAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF
Sbjct: 543 STMKIKXIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF 385

 Score = 71.6 bits (174), Expect(3) = e-123,   Method: Compositional matrix adjust.
 Identities = 33/34 (97%), Positives = 34/34 (100%)
 Frame = -1

Query: 140  LSLYASGRTTGIVMDSGDGVTHTVPIYEGYALPH 173
            LSLYASGRTTGIV+DSGDGVTHTVPIYEGYALPH
Sbjct: 1094 LSLYASGRTTGIVLDSGDGVTHTVPIYEGYALPH 993
>12322
          Length = 849

 Score =  239 bits (609), Expect = 2e-63,   Method: Compositional matrix adjust.
 Identities = 113/217 (52%), Positives = 151/217 (69%)
 Frame = +1

Query: 159 VTHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCY 218
           VTH VP+YEG+A+PH+I+R+D+AGRD+T YL  +L + G    TTAE E+V+ IKE+ CY
Sbjct: 1   VTHAVPVYEGFAMPHSIMRVDVAGRDVTRYLRLLLRKEGMDLHTTAEFEVVKHIKERTCY 180

Query: 219 VALDFEQEMATAASSSSLEKSYELPDGQVITIGNERFRCPEALFQPSFLGMESCGIHETT 278
           ++++  +E     S  + + SY LPDG  + +G  RFR PE LF+P  +G E  GIHE  
Sbjct: 181 LSINPLKE----ESVDTEKVSYTLPDGNTVEVGPARFRAPELLFRPDLIGEECEGIHEVL 348

Query: 279 FNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYS 338
             SI K DVD+RK LY+N VLSGG+T++ G  DR+  E+  LAP  +KI+I AP ER YS
Sbjct: 349 SYSIQKSDVDLRKTLYSNIVLSGGSTLFKGFGDRLLSELKKLAPKDIKIRISAPQERLYS 528

Query: 339 VWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF 375
            WIG SILASL TF++MW+SK+EY E G   +HRK F
Sbjct: 529 TWIGXSILASLDTFRKMWVSKREYHEEGVKAIHRKTF 639
>00608
          Length = 1930

 Score =  199 bits (507), Expect = 1e-51,   Method: Compositional matrix adjust.
 Identities = 121/333 (36%), Positives = 181/333 (54%), Gaps = 32/333 (9%)
 Frame = +3

Query: 75  IVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYV 134
           I+ +WD ME+ +    +  LR  PE+H  LLTE PLN   NRE   +IMFE+FN P +Y+
Sbjct: 3   IIDDWDLMERFYEQVIFKYLRAEPEDHYFLLTEPPLNTPENREYTAEIMFESFNVPGLYI 182

Query: 135 AIQAVLSLYASGRT--------TGIVMDSGDGVTHTVPIYEGYALPHAILRLDLAGRDLT 186
           A+QAVL+L AS  +        TG V+DSGDGVTH +P+ EGY +   I  + +AGRD+T
Sbjct: 183 AVQAVLALAASWTSRNVGERTLTGTVIDSGDGVTHVIPVAEGYVIGSCIKHIPIAGRDIT 362

Query: 187 DYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASS-SSLEKSYELPD- 244
            ++ ++L ER          E  + IKE+  YV  D  +E +   +  S   K YE  + 
Sbjct: 363 YFIQQLLREREVGIPPEQSLETAKAIKERFSYVCPDIAKEFSKYDTDPSKWMKKYEGRNT 542

Query: 245 --GQV--ITIGNERFRCPEALFQPSFLGME-SCGIHETTFNSIMKCDVDIRKDLYANTVL 299
              Q+  + +G ERF  PE  F P F   + +  I +   + I  C +D+R+ LY N VL
Sbjct: 543 ISKQLFSVDVGYERFLGPEIFFHPEFSNPDFTMPISDVVDDVIQNCPIDVRRGLYKNIVL 722

Query: 300 SGGTTMYPGIADRMQKEIT----------------ALAPSTMKIKIIAPPERKYSVWIGG 343
           SGG+TM+     ++Q+++                  + P  +++++I    ++Y+VW GG
Sbjct: 723 SGGSTMFRDFGRKIQRDVKRVVDGRLKASEELSQGRIKPKPIEVQVITHHMQRYAVWFGG 902

Query: 344 SILASLSTFQQMWISKQEYDESGPSIV-HRKCF 375
           S+LAS   F Q+  +K +YDE GPSI  H   F
Sbjct: 903 SMLASTPEFYQVCHTKADYDEHGPSICRHNPVF 1001
>01436
          Length = 2563

 Score =  176 bits (445), Expect = 2e-44,   Method: Compositional matrix adjust.
 Identities = 87/200 (43%), Positives = 123/200 (61%), Gaps = 12/200 (6%)
 Frame = +3

Query: 185 LTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELPD 244
           +T YL+K+L  RGY+F  +A+ E VR +KEKLCY A D EQE   A  ++ L + Y LPD
Sbjct: 3   ITRYLIKLLLLRGYAFNHSADFETVRMLKEKLCYTAYDVEQEQKLALETTVLVEPYILPD 182

Query: 245 GQVITIGNERFRCPEALFQPSFLGMESCGIHETTFNSIMKCDVDIRKDLYANTVLSGGTT 304
           G+VI +G ERF  PEALFQP  + ++  G+ E  FN+I   D+DIR D Y + VLSGG+T
Sbjct: 183 GRVIKVGGERFEAPEALFQPHLINVDGVGVAELLFNTIQAADMDIRPDFYKHIVLSGGST 362

Query: 305 MYPGIADRMQKEITAL-----------APSTMKIKIIAPPERKYSVWIGGSILAS-LSTF 352
           MYPG+  R+++EI  L             S  KI+I  PP RK+ V++GGS+ A  +   
Sbjct: 363 MYPGLPSRLEREIKQLYLERVLXGDTSRLSKFKIRIEDPPRRKHMVFLGGSVXADIMKDK 542

Query: 353 QQMWISKQEYDESGPSIVHR 372
              W+ + EY+E G  ++ +
Sbjct: 543 DDFWMMRSEYEEMGVKVLDK 602
>11487
          Length = 771

 Score = 96.3 bits (238), Expect(3) = 7e-43,   Method: Compositional matrix adjust.
 Identities = 43/43 (100%), Positives = 43/43 (100%)
 Frame = -2

Query: 333 PERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF 375
           PERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF
Sbjct: 602 PERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF 474

 Score = 84.3 bits (207), Expect(3) = 7e-43,   Method: Compositional matrix adjust.
 Identities = 38/41 (92%), Positives = 40/41 (97%)
 Frame = -1

Query: 276 ETTFNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKE 316
           ET +NSIMKCDVDIRKDLYANTVLSGGTTM+PGIADRMQKE
Sbjct: 771 ETAYNSIMKCDVDIRKDLYANTVLSGGTTMFPGIADRMQKE 649

 Score = 32.0 bits (71), Expect(3) = 7e-43,   Method: Compositional matrix adjust.
 Identities = 15/18 (83%), Positives = 16/18 (88%)
 Frame = -3

Query: 315 KEITALAPSTMKIKIIAP 332
           + ITALAP TMKIKIIAP
Sbjct: 655 ERITALAPPTMKIKIIAP 602
>19721
          Length = 757

 Score =  100 bits (249), Expect(2) = 7e-33,   Method: Compositional matrix adjust.
 Identities = 57/120 (47%), Positives = 76/120 (63%), Gaps = 8/120 (6%)
 Frame = +2

Query: 75  IVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYV 134
           +V +WD  E+      +  LR  PE+H  LLTE PLN   NRE   +IMFETFN P +Y+
Sbjct: 2   VVEDWDLHERFMEQAIFKYLRAEPEDHYFLLTEPPLNTPENREFTAEIMFETFNIPGLYI 181

Query: 135 AIQAVLSLYASGRT--------TGIVMDSGDGVTHTVPIYEGYALPHAILRLDLAGRDLT 186
           A+QAVL+L AS  +        TG V+DSGDGVTH +P+ +GY +  AI  + +AGRD+T
Sbjct: 182 AVQAVLALAASWTSRPPNERTLTGTVIDSGDGVTHVIPVVDGYVIGSAIKHIPIAGRDIT 361

 Score = 58.2 bits (139), Expect(2) = 7e-33,   Method: Compositional matrix adjust.
 Identities = 36/108 (33%), Positives = 52/108 (48%), Gaps = 8/108 (7%)
 Frame = +3

Query: 207 EIVRDIKEKLCYVALDFEQEMATAAS-------SSSLEKSYELPDGQVITIGNERFRCPE 259
           E  + IKE+  YV  D  +E A   S       +  +  S + PD     +G E+F  PE
Sbjct: 420 EAAKQIKERYSYVCPDIAKEFAKYDSDPEKWIKAHKMSGSSKYPDFS-FDVGYEKFLGPE 596

Query: 260 ALFQPSFL-GMESCGIHETTFNSIMKCDVDIRKDLYANTVLSGGTTMY 306
             F+P F+ G     I +     I  C +D R+ LY N VLSGG++M+
Sbjct: 597 VFFRPEFVNGDFQASISDVVDTVIQSCPIDSRRPLYNNIVLSGGSSMF 740
>36954
          Length = 892

 Score =  123 bits (308), Expect = 1e-28,   Method: Compositional matrix adjust.
 Identities = 66/189 (34%), Positives = 107/189 (56%), Gaps = 9/189 (4%)
 Frame = -1

Query: 3   DDIAALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKR 62
           D++ ALV D GS   +AG+AG+D P+A  P+ VG        +     D+    E +   
Sbjct: 817 DEVGALVFDIGSYSFRAGYAGEDTPKAEIPTHVGVMEDIETTMDTDGGDAPPQPEKKYLI 638

Query: 63  GILTLKYP---------IEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPK 113
             + +K+P         ++ G+V +WD  EK+  + +   ++     HP+L++E   N K
Sbjct: 637 DTVYMKHPRKGMHLNSFLKDGMVEDWDMFEKVIDYAYNRSIKSESCLHPLLMSEPAWNTK 458

Query: 114 ANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHTVPIYEGYALPH 173
           A REK+T+IMFE +N PA ++   +VLS +A+GR+T +++DSG   T  VP+Y+GY L  
Sbjct: 457 AKREKLTEIMFEKYNIPAFFLRKNSVLSAFANGRSTALILDSGATHTSAVPVYDGYVLTQ 278

Query: 174 AILRLDLAG 182
            I++  LAG
Sbjct: 277 GIVKSPLAG 251
>32273
          Length = 265

 Score =  123 bits (308), Expect = 1e-28,   Method: Compositional matrix adjust.
 Identities = 51/88 (57%), Positives = 74/88 (84%), Gaps = 1/88 (1%)
 Frame = -2

Query: 64  ILTLKYPIEHGIVTNWDDMEKIWHHTF-YNELRVAPEEHPVLLTEAPLNPKANREKMTQI 122
           +++++YP+EHGIV +W+DME+IW + +  ++L+   EEHPVLLTEAPLNP+ NREK  +I
Sbjct: 264 LMSIRYPMEHGIVKDWNDMERIWQYIYSKDQLQTFSEEHPVLLTEAPLNPRRNREKAAEI 85

Query: 123 MFETFNTPAMYVAIQAVLSLYASGRTTG 150
            F+TFN PA+++++QAVLSLYA+GR TG
Sbjct: 84  FFDTFNVPALFISMQAVLSLYATGRITG 1
>18926
          Length = 478

 Score =  111 bits (277), Expect(2) = 3e-25,   Method: Compositional matrix adjust.
 Identities = 49/105 (46%), Positives = 69/105 (65%), Gaps = 3/105 (2%)
 Frame = +1

Query: 273 GIHETTFNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAP 332
           G+      S+  CD+DIR  LY   +  GG ++  G  +R+ ++++   P +M++KIIA 
Sbjct: 97  GVGHVVTTSVGMCDIDIRPSLYGGVIAVGGNSLIQGFTERLNRDLSNKTPPSMRLKIIAA 276

Query: 333 P---ERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKC 374
               ER++S WIGGSILASL +FQQMW+SKQEY+E G S V RKC
Sbjct: 277 ASTAERRFSSWIGGSILASLGSFQQMWVSKQEYEEGGKSCVERKC 411

 Score = 21.9 bits (45), Expect(2) = 3e-25,   Method: Compositional matrix adjust.
 Identities = 12/35 (34%), Positives = 16/35 (45%), Gaps = 9/35 (25%)
 Frame = +3

Query: 252 NERFRCPEALFQPSFL---------GMESCGIHET 277
           +ERF+  E LF PS +         G   CG H+ 
Sbjct: 21  SERFKVCEGLFDPSVIKESQGNSSAGGGPCGHHQC 125
>13361
          Length = 1217

 Score = 93.2 bits (230), Expect = 2e-19,   Method: Compositional matrix adjust.
 Identities = 56/176 (31%), Positives = 85/176 (48%), Gaps = 23/176 (13%)
 Frame = +3

Query: 217 CYVALDFEQEMATAASS-SSLEKSYE-----LPDGQVITIGNERFRCPEALFQPSFLGME 270
           CY+  D  +E A   S  S   ++Y            + +G ERF  PE  F P F   +
Sbjct: 42  CYICPDIAKEFAKYDSEPSKWIRNYTGMNTVTKQAFNVDVGYERFLGPEIFFHPEFSNPD 221

Query: 271 -SCGIHETTFNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEIT----------- 318
            +  + E   N I  C +D+R+ LY N VLSGG+TM+     R+Q++I            
Sbjct: 222 FTIPLSEIVDNVIQNCPIDVRRHLYNNIVLSGGSTMFKDFGRRLQRDIKRSVDTRLRISE 401

Query: 319 -----ALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSI 369
                 + P  + +++I    ++Y+VW GGS+LAS   F Q+  +K  Y+E GPSI
Sbjct: 402 NLSEGRIKPKPIDVQVITHHMQRYAVWFGGSMLASTPEFYQVCHTKAAYEEYGPSI 569
>17032
          Length = 2938

 Score = 35.0 bits (79), Expect = 0.044,   Method: Compositional matrix adjust.
 Identities = 16/30 (53%), Positives = 20/30 (66%)
 Frame = -1

Query: 341  IGGSILASLSTFQQMWISKQEYDESGPSIV 370
             GGS+LAS   F Q+  +K +YDE GPSI 
Sbjct: 2938 FGGSMLASTPEFYQVCHTKADYDEHGPSIC 2849
>06132
          Length = 1490

 Score = 30.0 bits (66), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 21/67 (31%), Positives = 29/67 (43%), Gaps = 7/67 (10%)
 Frame = -2

Query: 220  ALDFEQEMATAASSSSLEKSYELPDGQVITIGNERFRCPEALFQPSF-------LGMESC 272
            AL F+Q M T    +S  + Y  P+ + +T+G      P    Q  +       LGM   
Sbjct: 1015 ALLFQQLMCTTLEKNSHHRLYVSPNHRKLTLGCPVLMLPHDARQDMY*NANCYVLGMTQL 836

Query: 273  GIHETTF 279
            GI  TTF
Sbjct: 835  GIELTTF 815
>06084
          Length = 1739

 Score = 27.7 bits (60), Expect = 7.5,   Method: Compositional matrix adjust.
 Identities = 11/18 (61%), Positives = 13/18 (72%)
 Frame = +3

Query: 333 PERKYSVWIGGSILASLS 350
           P+RKY VW+ G I  SLS
Sbjct: 981 PQRKYGVWVRGGITRSLS 1034
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6671557|ref|NP_031482.1| adaptor-related protein
complex AP-1, mu subunit 1 [Mus musculus]
         (423 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

04701                                                                 625   0.0  
08361                                                                 169   2e-42
06056                                                                  69   2e-20
30493                                                                  83   2e-16
29016                                                                  67   2e-11
28998                                                                  65   6e-11
33122                                                                  39   0.004
04375                                                                  30   1.6  
36011                                                                  28   5.0  
>04701
          Length = 4543

 Score =  625 bits (1611), Expect(2) = 0.0,   Method: Compositional matrix adjust.
 Identities = 299/332 (90%), Positives = 317/332 (95%)
 Frame = +2

Query: 91  FSEYFKELEEESIRDNFVIIYELLDELMDFGYPQTTDSKILQEYITQEGHKLETGAPRPP 150
           F EYFKELEEESIRDNFVIIYELLDE+MDFGYPQTTDSKILQEYITQEG KLE  APRPP
Sbjct: 356 FVEYFKELEEESIRDNFVIIYELLDEVMDFGYPQTTDSKILQEYITQEGQKLEV-APRPP 532

Query: 151 ATVTNAVSWRSEGIKYRKNEVFLDVIEAVNLLVSANGNVLRSEIVGSIKMRVFLSGMPEL 210
             VTNAVSWRSEG+KYRKNEVFLDVIE+VNLLVSANGNVLRSEIVGS+KMRVFLSGMPEL
Sbjct: 533 MAVTNAVSWRSEGVKYRKNEVFLDVIESVNLLVSANGNVLRSEIVGSVKMRVFLSGMPEL 712

Query: 211 RLGLNDKVLFDNTGRGKSKSVELEDVKFHQCVRLSRFENDRTISFIPPDGEFELMSYRLN 270
           RLGLNDKVLF++TGRGKSKSVELEDVKFHQCVRLSRFENDRTISFIPPDGEFELMSYRLN
Sbjct: 713 RLGLNDKVLFESTGRGKSKSVELEDVKFHQCVRLSRFENDRTISFIPPDGEFELMSYRLN 892

Query: 271 THVKPLIWIESVIEKHSHSRIEYMVKAKSQFKRRSTANNVEIHIPVPNDADSPKFKTTVG 330
           THVKPLIW+ESVIE+H HSR+EYM+KAKSQFKRRSTANNVEI IPVP DADSPKFKTTVG
Sbjct: 893 THVKPLIWVESVIERHVHSRVEYMIKAKSQFKRRSTANNVEIIIPVPADADSPKFKTTVG 1072

Query: 331 SVKWVPENSEIVWSVKSFPGGKEYLMRAHFGLPSVEAEDKEGKPPISVKFEIPYFTTSGI 390
           S K+VPE + ++WS+KSFPGGKE+LMRAHFGLPSVE ED EG+PPIS+KFEIPYFT SGI
Sbjct: 1073SCKYVPEINSVIWSIKSFPGGKEFLMRAHFGLPSVENEDAEGRPPISIKFEIPYFTVSGI 1252

Query: 391 QVRYLKIIEKSGYQALPWVRYITQNGDYQLRT 422
           QVRYLKIIEKSGYQALPWVRYITQNGDYQLRT
Sbjct: 1253QVRYLKIIEKSGYQALPWVRYITQNGDYQLRT 1348

 Score =  134 bits (336), Expect(2) = 0.0,   Method: Compositional matrix adjust.
 Identities = 57/91 (62%), Positives = 81/91 (89%)
 Frame = +3

Query: 1   MSASAVYVLDLKGKVLICRNYRGDVDMSEVEHFMPILMEKEEEGMLSPILAHGGVRFMWI 60
           MSASA+Y+LD+KGKVLI RNYRGD+DMS ++ FMP++ME E++  ++PI++HG V F++I
Sbjct: 87  MSASAIYILDVKGKVLISRNYRGDIDMSVIDKFMPLVMEGEDDSNVTPIISHGNVTFVYI 266

Query: 61  KHNNLYLVATSKKNACVSLVFSFLYKVVQVF 91
           K+NNLYLV+T++KNA V+LVFSFL+K+VQ+ 
Sbjct: 267 KYNNLYLVSTTRKNANVALVFSFLHKLVQIL 359
>08361
          Length = 465

 Score =  169 bits (427), Expect = 2e-42,   Method: Compositional matrix adjust.
 Identities = 76/147 (51%), Positives = 108/147 (73%), Gaps = 2/147 (1%)
 Frame = -3

Query: 81  FSFLYKVVQVFSEYFKELEEESIRDNFVIIYELLDELMDFGYPQTTDSKILQEYITQEGH 140
           F FL+K+ +V   YF ++ EE+I++NFV+IYE+LDE++D+GYPQ TD+ IL+ +ITQ+G 
Sbjct: 463 FEFLHKIAEVMQAYFGKISEENIKNNFVLIYEILDEILDYGYPQNTDTGILKTFITQQGI 284

Query: 141 KLETGAPRPPAT--VTNAVSWRSEGIKYRKNEVFLDVIEAVNLLVSANGNVLRSEIVGSI 198
           K ++       T  VT  + WR EGIKYR+NE+FLDV+E+VNLL+S  G VL + + G I
Sbjct: 283 KSQSKEDTAQITSQVTGQIGWRREGIKYRRNELFLDVLESVNLLMSPQGQVLSAHVAGRI 104

Query: 199 KMRVFLSGMPELRLGLNDKVLFDNTGR 225
            M+ +LSGMPE + G+NDKVL D  G+
Sbjct: 103 VMKSYLSGMPECKFGINDKVLMDTKGK 23
>06056
          Length = 1228

 Score = 68.6 bits (166), Expect(2) = 2e-20,   Method: Compositional matrix adjust.
 Identities = 41/132 (31%), Positives = 62/132 (46%)
 Frame = -2

Query: 257  PPDGEFELMSYRLNTHVKPLIWIESVIEKHSHSRIEYMVKAKSQFKRRSTANNVEIHIPV 316
            PPDGEFELM YR    +     +  ++ +    ++E  V  KS FK    A  VE+ IP 
Sbjct: 1104 PPDGEFELMRYRTTNDISLPFRVIPLVREVGRQKMEVKVVVKSNFKPSLAAQKVELRIPT 925

Query: 317  PNDADSPKFKTTVGSVKWVPENSEIVWSVKSFPGGKEYLMRAHFGLPSVEAEDKEGKPPI 376
            P +    +     G  K+   ++ IVW +K   G KE  + A   L +   + K  +PP+
Sbjct: 924  PLNTSGVQVICMKGXAKYKASDNAIVWKIKRIGGMKECQLSAEIELLATSDKKKWTRPPL 745

Query: 377  SVKFEIPYFTTS 388
            S    +P F +S
Sbjct: 744  S----MPVFLSS 721

 Score = 48.5 bits (114), Expect(2) = 2e-20,   Method: Compositional matrix adjust.
 Identities = 20/39 (51%), Positives = 29/39 (74%)
 Frame = -3

Query: 222  NTGRGKSKSVELEDVKFHQCVRLSRFENDRTISFIPPDG 260
              G GK+ S+ ++D +FHQCV+LS+FE + +ISFIP  G
Sbjct: 1205 GAGAGKT-SIAIDDCQFHQCVKLSKFETEHSISFIPLXG 1092
>30493
          Length = 657

 Score = 83.2 bits (204), Expect = 2e-16,   Method: Compositional matrix adjust.
 Identities = 48/139 (34%), Positives = 71/139 (51%), Gaps = 4/139 (2%)
 Frame = -2

Query: 288 HSRIEYMVKAKSQFKRRSTANNVEIHIPVPNDADSPKFKTTVGSVKWVPENSEIVWSVKS 347
             ++E  V  KS FK    A  VE+ IP P +    +     G  K+   ++ IVW +K 
Sbjct: 569 RQKMEVKVVVKSNFKPSLAAQKVELRIPTPLNTSGVQVICMKGRAKYKASDNAIVWKIKR 390

Query: 348 FPGGKEYLMRAHFGLPSVEAEDKEGKPPISVKFEIPYFTTSGIQVRYLKIIEK----SGY 403
             G KE  + A   L +   + K  +PP+S+ FE+P F  SG +VRYLK+ E     S +
Sbjct: 389 IGGMKECQLSAEIELLATSDKKKWTRPPLSMNFEVP-FAPSGFKVRYLKVFESKINYSDH 213

Query: 404 QALPWVRYITQNGDYQLRT 422
             + WVRYI ++G Y+ R 
Sbjct: 212 DVIKWVRYIGRSGLYETRC 156
>29016
          Length = 550

 Score = 66.6 bits (161), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 28/44 (63%), Positives = 37/44 (84%)
 Frame = +2

Query: 223 TGRGKSKSVELEDVKFHQCVRLSRFENDRTISFIPPDGEFELMS 266
            G GK+ S+ ++D +FHQCV+LS+FE + +ISFIPPDGEFELMS
Sbjct: 2   AGAGKT-SIAIDDCQFHQCVKLSKFETEHSISFIPPDGEFELMS 130
>28998
          Length = 569

 Score = 64.7 bits (156), Expect = 6e-11,   Method: Compositional matrix adjust.
 Identities = 27/43 (62%), Positives = 36/43 (83%)
 Frame = +2

Query: 223 TGRGKSKSVELEDVKFHQCVRLSRFENDRTISFIPPDGEFELM 265
            G GK+ S+ ++D +FHQCV+LS+FE + +ISFIPPDGEFELM
Sbjct: 2   AGAGKT-SIAIDDCQFHQCVKLSKFETEHSISFIPPDGEFELM 127
>33122
          Length = 465

 Score = 38.9 bits (89), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 24/96 (25%), Positives = 48/96 (50%), Gaps = 9/96 (9%)
 Frame = -3

Query: 231 VELEDVKFHQCVRLSRFENDRTISFIPPDG-EFELMSYRL----NTHVKPLIWIESVI-E 284
           +++ED +FH  V L  +EN   + F P D  +FEL+ +R+    N  +   + ++ ++ +
Sbjct: 436 IKIEDPEFHCVVDLDTYENTNNLRFHPLDACQFELLRFRVRPRENKELPLQLHVQQIMKD 257

Query: 285 KHSHSRIEYMVKAKSQFKRRS---TANNVEIHIPVP 317
           +H   R + +V     F ++       ++EIH  +P
Sbjct: 256 RHFEIRCBMLVTGYHAFSKKCGQFPCEDIEIHFKIP 149
>04375
          Length = 2667

 Score = 30.4 bits (67), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 27/109 (24%), Positives = 47/109 (43%), Gaps = 13/109 (11%)
 Frame = +3

Query: 55  VRFMWIKHNNLYLVATSKKNACVSLVFSFLYKVVQVFSEYFKELEEESIRDNFVIIYELL 114
           ++ ++ ++ +LY     +      L    +++ V++  +YF  + E  I  NF   + +L
Sbjct: 264 LKVVYKRYASLYFCCAIEPEDNELLTLEIIHRYVELLDKYFGSVCELDIIFNFEKAFFML 443

Query: 115 DELMDFGYPQTTDSK----------ILQEYITQEGHKLETGA---PRPP 150
           DE M  G  Q T  K          +LQE  T +G   + G    P PP
Sbjct: 444 DEFMLGGEVQETSKKNVLKAIAAQDLLQEEETPQGFFEDHGLG*HPSPP 590
>36011
          Length = 343

 Score = 28.5 bits (62), Expect = 5.0,   Method: Composition-based stats.
 Identities = 15/60 (25%), Positives = 28/60 (46%)
 Frame = -1

Query: 270 NTHVKPLIWIESVIEKHSHSRIEYMVKAKSQFKRRSTANNVEIHIPVPNDADSPKFKTTV 329
           N H K +   ++V++ H HS  +++            + +  +  P+PN   SPK+K  V
Sbjct: 268 NNH*KAIFNFDAVLKHHFHSNSKFV-----------NSCSRSLQTPLPNXPPSPKYKQQV 122
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6671702|ref|NP_031663.1| chaperonin containing Tcp1,
subunit 5 (epsilon) [Mus musculus]
         (541 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

01159                                                                 828   0.0  
12796                                                                 197   1e-50
05356                                                                 104   1e-45
29631                                                                  92   3e-45
06409                                                                 174   6e-44
02673                                                                 158   7e-39
09900                                                                 115   5e-26
29864                                                                 106   2e-23
33770                                                                  94   2e-19
30661                                                                  85   8e-17
10291                                                                  67   2e-11
17249                                                                  45   6e-05
09856                                                                  30   1.7  
29327                                                                  30   1.8  
21277                                                                  28   9.8  
>01159
          Length = 2613

 Score =  828 bits (2139), Expect = 0.0,   Method: Compositional matrix adjust.
 Identities = 397/539 (73%), Positives = 468/539 (86%), Gaps = 1/539 (0%)
 Frame = +3

Query: 1   MAS-VGTLAFDEYGRPFLIIKDQDRKSRLMGLEALKSHIMAAKAVANTMRTSLGPNGLDK 59
           MAS +G +AFDEYGRPF+I++DQD+KSRL G+EA KSHI+AAK+VA+ ++TSLGP GLDK
Sbjct: 90  MASPMGQIAFDEYGRPFIILRDQDKKSRLTGIEAHKSHILAAKSVASILKTSLGPKGLDK 269

Query: 60  MMVDKDGDVTITNDGATILSMMDVDHQIAKLMVELSKSQDDEIGDXXXXXXXXXXXXXXX 119
           MMV  DGDVT+TNDGATIL MMDVDHQIAKLMV+LSKSQDDEIGD               
Sbjct: 270 MMVSGDGDVTVTNDGATILDMMDVDHQIAKLMVQLSKSQDDEIGDGTTGVVVLAGALLEQ 449

Query: 120 XXQLLDRGIHPIRIADGYEQAARIAIQHLDKISDKVLVDINNPEPLIQTAKTTLGSKVIN 179
             +LLDRGIHPIRIADGYE AA+ A++ LDKISD   VD+ N EPLI+ A TTLGSK++N
Sbjct: 450 AEKLLDRGIHPIRIADGYEIAAKCAVETLDKISDNYEVDLKNAEPLIKLAMTTLGSKIVN 629

Query: 180 SCHRQMAEIAVNAVLTVADMERRDVDFELIKVEGKVGGRLEDTKLIKGVIVDKDFSHPQM 239
            CHRQMA+IAV+A+++VAD++R+DVDFELIKVEGKVGG+LEDT L+KGV+VDKD SHPQM
Sbjct: 630 RCHRQMAKIAVDAIMSVADLKRKDVDFELIKVEGKVGGKLEDTMLVKGVVVDKDMSHPQM 809

Query: 240 PKKVVDAKIAILTCPFEPPKPKTKHKLDVMSVEDYKALQKYEKEKFEEMIKQIKETGANL 299
           PK V DAKIAILTCPFEPPKPKTKHKLD+ SVEDYK L++YE  KFE M++ +K+ GANL
Sbjct: 810 PKVVKDAKIAILTCPFEPPKPKTKHKLDITSVEDYKKLREYELNKFESMVQSVKDKGANL 989

Query: 300 AICQWGFDDEANHLLLQNGLPAVRWVGGPEIELIAIATGGRIVPRFSELTSEKLGFAGVV 359
            ICQWGFDDEANHLLLQ  LPAVRWVGGPEIELIAIATGGRIVPRF ELT+EKLG AG+V
Sbjct: 990 VICQWGFDDEANHLLLQRELPAVRWVGGPEIELIAIATGGRIVPRFEELTTEKLGKAGIV 1169

Query: 360 QEISFGTTKDKMLVIEKCKNSRAVTIFIRGGNKMIIEEAKRSLHDALCVIRNLIRDNRVV 419
           +E++FGTTKD+MLVIE+C N+RAVTIFIRGGNKMI+EEAKRSLHDALCVIRNL+RDNRVV
Sbjct: 1170RELTFGTTKDRMLVIEECLNTRAVTIFIRGGNKMIVEEAKRSLHDALCVIRNLVRDNRVV 1349

Query: 420 YGGGAAEISCALAVSQEADKCPTLEQYAMRAFADALEVIPMALSENSGMNPIQTMTEVRA 479
           YGGGA EI+ ++AV++ ADK  TLEQYA+R+F++ALE +P+AL+ENSG+ PIQT+ EV++
Sbjct: 1350YGGGAPEIAASVAVAEAADKISTLEQYAVRSFSEALEAVPLALAENSGLAPIQTLAEVKS 1529

Query: 480 RQVKESNPALGIDCLHKGSNDMQYQHVIETLIGKKQQISLATQMVRMILKIDDIRKPGE 538
           RQVKE NP LGIDCL KG+NDM+ Q+VIETL  KKQQI LATQ+VRMILKIDDIR P +
Sbjct: 1530RQVKEKNPRLGIDCLLKGTNDMKEQNVIETLTAKKQQILLATQLVRMILKIDDIRAPSD 1706
>12796
          Length = 1316

 Score =  197 bits (500), Expect = 1e-50,   Method: Compositional matrix adjust.
 Identities = 126/339 (37%), Positives = 188/339 (55%), Gaps = 9/339 (2%)
 Frame = -3

Query: 204  VDFELIKVEGKVGGRLEDTKLIKGVIVDKDFSHPQMPKKVVDAKIAILTCPFEPPKPKTK 263
            VD + IKV   +GG +EDT+L+ G++     +    PK++  AKI ++      PK    
Sbjct: 1308 VDLKNIKVIRSLGGTVEDTELVNGLVFTSRSAGTNAPKRIEKAKIGLIQFCISAPKTDMD 1129

Query: 264  HKLDVMSVEDYKALQKYEKEK---FEEMIKQIKETGANLAICQWGF-----DDEANHLLL 315
            H    + V DY A+ +  KE+      ++KQIK+ G N+ + Q         D A H L 
Sbjct: 1128 HN---VIVSDYAAMDRVLKEERSYILNIVKQIKKAGCNVLLVQKSILRDAVSDLAQHFLD 958

Query: 316  QNGLPAVRWVGGPEIELIAIATGGRIVPRFSELTSEKLGFAGVVQEISFGTTKDKMLVIE 375
            +     V+ V   +IE +      R +      T+E +  A +V+E++ GT  +K + I 
Sbjct: 957  KIKCLVVKDVEREDIEFVCKTLHCRPIASLDHFTAENMSSADLVEEVASGT--NKFVKIT 784

Query: 376  KCKN-SRAVTIFIRGGNKMIIEEAKRSLHDALCVIRNLIRDNRVVYGGGAAEISCALAVS 434
              +N  R V+I  RG NK+++EEA RSLHDALCV+R L+R+   + GGGA EI  AL ++
Sbjct: 783  GIQNQGRTVSIICRGSNKLVLEEAARSLHDALCVVRCLVRNRAQIVGGGAPEIEMALQLA 604

Query: 435  QEADKCPTLEQYAMRAFADALEVIPMALSENSGMNPIQTMTEVRARQVKESNPALGIDCL 494
              A     ++ Y  RAFADALEVIP  L+EN+G+NPI T+TE+R R  +    A GI+  
Sbjct: 603  AAAQTVDGVDAYCYRAFADALEVIPSTLAENAGLNPIATVTELRNRHAQGEKNA-GINVR 427

Query: 495  HKGSNDMQYQHVIETLIGKKQQISLATQMVRMILKIDDI 533
                 D+  ++V++ L+     I+LAT+ VR ILKIDDI
Sbjct: 426  KGAITDIFAENVVQPLLVSTSAITLATETVRSILKIDDI 310
>05356
          Length = 2339

 Score =  104 bits (259), Expect(2) = 1e-45,   Method: Compositional matrix adjust.
 Identities = 79/283 (27%), Positives = 143/283 (50%), Gaps = 3/283 (1%)
 Frame = +2

Query: 22  QDRKSRLMGL-EALKSHIMAAKAVANTMRTSLGPNGLDKMMVDKDGDVTITNDGATILSM 80
           +D      GL EA+  +I A K +A T R++ GP+G +KM+++    + +TND ATIL  
Sbjct: 236 KDGAKHFSGLDEAVYRNIEACKELAKTTRSAYGPHGQNKMVINHLEKLFVTNDAATILRE 415

Query: 81  MDVDHQIAKLMVELSKSQDDEIGDXXXXXXXXXXXXXXXXXQLLDRGIHPIRIADGYEQA 140
           ++V H  AK++V  +  Q+ E GD                 QLL  G+    + +GYE A
Sbjct: 416 LEVQHPAAKMLVLAAHQQEQECGDGTNFVLVFAGALLENAEQLLRMGLSVTEVIEGYELA 595

Query: 141 ARIAIQHLDKISDKVLVDINNPEPLIQTAKTTLGSKVINSCHRQMAEIAVNAVLTVADME 200
            + A + L K+    + ++ N E +    +T++ SK   +    +A++  +A ++V   +
Sbjct: 596 LKKAHEILPKLVIGHVKNLRNKEEVKTAIRTSVMSKQYGN-EDFLADLITDACVSVLPAK 772

Query: 201 RRDVDFEL--IKVEGKVGGRLEDTKLIKGVIVDKDFSHPQMPKKVVDAKIAILTCPFEPP 258
              + F +  ++V   +G  L  +  I+G++  +         KV  AK+A+ TCP +  
Sbjct: 773 ---ISFSVDNVRVCKILGCGLLQSSTIQGMVFKRQVEGE--ITKVEKAKVAVFTCPLDSM 937

Query: 259 KPKTKHKLDVMSVEDYKALQKYEKEKFEEMIKQIKETGANLAI 301
           + +TK  + + + E+  +  K E++  EE IK IKE G N+ +
Sbjct: 938 QTETKGTVLIKNAEELMSFSKGEEDMMEEQIKGIKEAGVNVIV 1066

 Score = 97.8 bits (242), Expect(2) = 1e-45,   Method: Compositional matrix adjust.
 Identities = 62/235 (26%), Positives = 120/235 (51%), Gaps = 3/235 (1%)
 Frame = +1

Query: 302  CQWG-FDDEANHLLLQNGLPAVRWVGGPEIELIAIATGGRIVPRFSELTSEKLGFAGVVQ 360
            C WG   D A H   +  +  +R +   ++  +  +     +P+ +   +E+ G+  +V 
Sbjct: 1063 CSWGEVGDLAQHYCNKYKVMVIRLLSKWDLRRLCKSICATALPKVTTPRNEECGYCDLVY 1242

Query: 361  EISFGTTKDKMLVIEKCKNSRAVT-IFIRGGNKMIIEEAKRSLHDALCVIRNLIRDNRVV 419
                G T   +++ ++ K+   +T + IRG    I+++ +R+L D +   + L +D+R+V
Sbjct: 1243 VDEIGETP--VVIFQQNKDESPITTVIIRGSTDNIMDDIERALDDGVNTFKALTKDDRLV 1416

Query: 420  YGGGAAEISCALAVSQEADKCPTLEQYAMRAFADALEVIPMALSENSGMNPIQTMTEVRA 479
             G GA EI  A  ++   +  P LEQYA++ FA++LEVIP AL+EN+GM     ++++ A
Sbjct: 1417 PGAGATEIELAKQITTYGESLPGLEQYAVKKFAESLEVIPRALAENTGMKATDILSKLYA 1596

Query: 480  RQVKESNPALGIDCLHKGSN-DMQYQHVIETLIGKKQQISLATQMVRMILKIDDI 533
               +E     G+D    GS  D +  ++ +  + +   +  A      +L++D I
Sbjct: 1597 AH-QEGQQNAGVDIDDSGSVLDAKQANLTDLYLNRYWGLKFAAAAACTVLRVDQI 1758
>29631
          Length = 1257

 Score = 91.7 bits (226), Expect(3) = 3e-45,   Method: Compositional matrix adjust.
 Identities = 57/190 (30%), Positives = 103/190 (54%), Gaps = 3/190 (1%)
 Frame = +1

Query: 168 TAKTTLGSKVINSCHRQMAEIAVNAVLTVADME--RRDVDFE-LIKVEGKVGGRLEDTKL 224
           ++++ LG+K I+       +IA++A  TV   E  R+++D +   KVE   GG +E++++
Sbjct: 451 SSQSCLGTKFISKWMDLACQIALDATTTVFMEENGRKEIDIKRYAKVEKIPGGTMEESEV 630

Query: 225 IKGVIVDKDFSHPQMPKKVVDAKIAILTCPFEPPKPKTKHKLDVMSVEDYKALQKYEKEK 284
           +KG+ V+KD  H +M +++ + +I +L C  E  K ++   +++   ED+  + + E+E 
Sbjct: 631 LKGIXVNKDVVHXKMKRRIENPRIMLLDCNLEYKKGESATNIEISKEEDFAKILQLEEEY 810

Query: 285 FEEMIKQIKETGANLAICQWGFDDEANHLLLQNGLPAVRWVGGPEIELIAIATGGRIVPR 344
             +M  +I     +L I + G  D A H LL+ G+  +R V   +   IA A G  I  R
Sbjct: 811 IRKMCDEIIALKPDLVITEKGVSDLAQHFLLKAGISVLRRVRKTDNNRIARACGATIANR 990

Query: 345 FSELTSEKLG 354
             EL  E +G
Sbjct: 991 TDELKEEDMG 1020

 Score = 76.6 bits (187), Expect(3) = 3e-45,   Method: Compositional matrix adjust.
 Identities = 42/124 (33%), Positives = 68/124 (54%)
 Frame = +3

Query: 17  LIIKDQDRKSRLMGLEALKSHIMAAKAVANTMRTSLGPNGLDKMMVDKDGDVTITNDGAT 76
           +I+ +Q+ + R  G +    +I A K +A+ +RT LGP  + KM++D  G + +TNDG  
Sbjct: 3   IIVLNQNTR-RESGRKVQLGNIAAGKTIADVIRTCLGPKSMLKMLMDPMGGIVMTNDGNA 179

Query: 77  ILSMMDVDHQIAKLMVELSKSQDDEIGDXXXXXXXXXXXXXXXXXQLLDRGIHPIRIADG 136
           IL  ++V H  AK M+E++++QD+E GD                 Q L++ +HP  I   
Sbjct: 180 ILREINVQHPAAKSMIEVARTQDEETGDGTKSVIILAGEVLSVAEQFLEQQMHPTVIIAA 359

Query: 137 YEQA 140
           Y QA
Sbjct: 360 YRQA 371

 Score = 53.5 bits (127), Expect(3) = 3e-45,   Method: Compositional matrix adjust.
 Identities = 26/66 (39%), Positives = 43/66 (65%)
 Frame = +3

Query: 369  DKMLVIEKCKNSRAVTIFIRGGNKMIIEEAKRSLHDALCVIRNLIRDNRVVYGGGAAEIS 428
            D    +  CK+ +A TI +RG +K I+ E +R+L DA+ V RN++ D  +  GGGA+E++
Sbjct: 1059 DYFTFLVDCKSPKACTILLRGASKDILAEVERNLQDAMNVARNVMIDPHLCPGGGASEMA 1238

Query: 429  CALAVS 434
             A A++
Sbjct: 1239 LAQALN 1256
>06409
          Length = 1533

 Score =  174 bits (442), Expect = 6e-44,   Method: Compositional matrix adjust.
 Identities = 104/303 (34%), Positives = 165/303 (54%), Gaps = 9/303 (2%)
 Frame = -3

Query: 240  PKKVVDAKIAILTCPFEPPKPKTKHKLDVMSVEDYKALQKYEKEKFEEMIKQIKETGANL 299
            P KV  AKI  +     PPK   ++++ V        + + E+    +++K+IK+ G N+
Sbjct: 1501 PSKVEKAKIGFIQFCISPPKTDMENQVIVSDYTQMDRVLREERNYILDIVKKIKKAGCNV 1322

Query: 300  AICQWGF-----DDEANHLLLQNGLPAVRWVGGPEIELIAIATGGRIVPRFSELTSEKLG 354
             + Q         D A H L +  +  V+ +   ++E +    G R V        E LG
Sbjct: 1321 LLIQKSILRDAVSDLALHFLAKMKIMVVKDIEREDVEFVCKTLGCRPVASLDHFLPENLG 1142

Query: 355  FAGVVQEISFGTTKDKMLVIEKCKN----SRAVTIFIRGGNKMIIEEAKRSLHDALCVIR 410
             A +++E+  G++K     I K        + VT+ IRG NK+++EEA RSLHDALCVIR
Sbjct: 1141 SADLIEEVQTGSSK-----IVKATGIANPGQTVTVLIRGSNKLVLEEADRSLHDALCVIR 977

Query: 411  NLIRDNRVVYGGGAAEISCALAVSQEADKCPTLEQYAMRAFADALEVIPMALSENSGMNP 470
             L++   ++ GGGA E   ++ ++  A+    +EQY  RAFA+ALEVIP  L+EN+G+NP
Sbjct: 976  CLVKKKALIAGGGAPETEMSMRLAAYANTLAGMEQYCFRAFAEALEVIPFTLAENAGLNP 797

Query: 471  IQTMTEVRARQVKESNPALGIDCLHKGSNDMQYQHVIETLIGKKQQISLATQMVRMILKI 530
            I T+T +R R  +    A GI+       ++  ++V++ L+     I+LA++ VR ILKI
Sbjct: 796  ISTVTXLRTRHAQGERTA-GINVRKGAITNILEENVLQPLLVSTSAITLASETVRSILKI 620

Query: 531  DDI 533
            DDI
Sbjct: 619  DDI 611
>02673
          Length = 1243

 Score =  158 bits (399), Expect = 7e-39,   Method: Compositional matrix adjust.
 Identities = 78/116 (67%), Positives = 99/116 (85%)
 Frame = +1

Query: 423 GAAEISCALAVSQEADKCPTLEQYAMRAFADALEVIPMALSENSGMNPIQTMTEVRARQV 482
           GA EI+ ++AV++ ADK  TLEQYA+R+F++ALE +P+AL+ENSG+ PIQT+ EV++RQV
Sbjct: 1   GAPEIAASVAVAEAADKISTLEQYAVRSFSEALEAVPLALAENSGLAPIQTLAEVKSRQV 180

Query: 483 KESNPALGIDCLHKGSNDMQYQHVIETLIGKKQQISLATQMVRMILKIDDIRKPGE 538
           KE NP LGIDCL KG+NDM+ Q+VIETL  KKQQI LATQ+VRMILKIDDIR P +
Sbjct: 181 KEKNPRLGIDCLLKGTNDMKEQNVIETLTAKKQQILLATQLVRMILKIDDIRAPSD 348
>09900
          Length = 1305

 Score =  115 bits (287), Expect = 5e-26,   Method: Compositional matrix adjust.
 Identities = 77/291 (26%), Positives = 141/291 (48%), Gaps = 1/291 (0%)
 Frame = +3

Query: 247 KIAILTCPFEPPKPKTKHKLDVMSVEDYKALQKYEKEKFEEMIKQIKETGANLAICQWGF 306
           +IA+L    E    +   ++ V +V++Y+++   E +   + + +I ++GA + + +   
Sbjct: 60  RIALLNIELELKSERDNAEVRVDNVQEYQSIVDAEWKILYDKLDKIHQSGAKVVLSKLPI 239

Query: 307 DDEANHLLLQNGLPAVRWVGGPEIELIAIATGGRIVPRFSELTSEKLGFAGVVQEISFGT 366
            D A        +     V   ++     A GG I      LT + LG   +  EI  G 
Sbjct: 240 GDVATQYFADRDMFCAGRVPEEDLRRTMKACGGSIQTTVQSLTPDVLGTCQLFDEIQIGG 419

Query: 367 TKDKMLVIEKCKNSRAVTIFIRGGNKMIIEEAKRSLHDALCVIRNLIRDNRVVYGGGAAE 426
            +  M   + C  +R  TI +RGG +  +EE +RSLHDA+ ++R  I+++ VV GGGA E
Sbjct: 420 ERFNMF--KGCTMARTCTIILRGGAEQFMEETERSLHDAIMIVRRAIKNDSVVAGGGAIE 593

Query: 427 ISCALAVSQEADKCPTLEQYAMRAFADALEVIPMALSENSGMNPIQTMTEVRARQVKESN 486
           +  +  + + +      EQ  M A+A ALEVIP  L +N+G +    + ++R +   +  
Sbjct: 594 MEVSYHLREHSHTIAGKEQLLMSAYAKALEVIPRQLCDNAGFDATNILNKLRQKHA-QGG 770

Query: 487 PALGIDCLHKGSNDMQYQHVIETLIGKKQQISLATQMVRMILKIDD-IRKP 536
              G++ L +   D     V E  + K   ++ A++   +IL +D+ I+ P
Sbjct: 771 TWYGVNILREDIADNFEDCVWEPAVVKINALTAASEATALILSVDETIKNP 923
>29864
          Length = 1026

 Score =  106 bits (264), Expect = 2e-23,   Method: Compositional matrix adjust.
 Identities = 78/251 (31%), Positives = 123/251 (49%)
 Frame = +1

Query: 32  EALKSHIMAAKAVANTMRTSLGPNGLDKMMVDKDGDVTITNDGATILSMMDVDHQIAKLM 91
           +AL  +I AAK + + +R++LGP G  KM+V   GD+ +T DG  +L  M + H  A L+
Sbjct: 160 QALAVNIAAAKGLQDVLRSNLGPKGTMKMLVSGAGDIKLTKDGNVLLHEMQIQHPTASLI 339

Query: 92  VELSKSQDDEIGDXXXXXXXXXXXXXXXXXQLLDRGIHPIRIADGYEQAARIAIQHLDKI 151
             ++ +QDD  GD                   +  G+HP  I +G+E A   A++ L+++
Sbjct: 340 ARVATAQDDITGDGTTSNVLIIGELLKQADLYIAEGLHPRLITEGFELARNKALEVLEEV 519

Query: 152 SDKVLVDINNPEPLIQTAKTTLGSKVINSCHRQMAEIAVNAVLTVADMERRDVDFELIKV 211
             K  VD    E L+Q A+T+L +KV       + E  V+AVL +       +D  ++++
Sbjct: 520 KVKREVD---RETLVQVARTSLRTKVHTELADLLTEHVVDAVLAI-QXPGEGIDLHMVEL 687

Query: 212 EGKVGGRLEDTKLIKGVIVDKDFSHPQMPKKVVDAKIAILTCPFEPPKPKTKHKLDVMSV 271
                    D+ L++G+++D    HP M K   DA   ILTC       KT    +V S 
Sbjct: 688 MEMQHKTDLDSTLVRGLVMDHGARHPDMKKHTKDA--FILTCNVSLEYEKT----EVNSG 849

Query: 272 EDYKALQKYEK 282
             YK  Q+ EK
Sbjct: 850 FFYKTAQEREK 882
>33770
          Length = 484

 Score = 94.0 bits (232), Expect = 2e-19,   Method: Compositional matrix adjust.
 Identities = 65/163 (39%), Positives = 98/163 (60%), Gaps = 1/163 (0%)
 Frame = +1

Query: 59  KMMVDKDGDVTITNDGATILSMMDVDHQIAKLMVELSKSQDDEIGDXXXXXXXXXXXXXX 118
           KM+   +GDVTITNDGATIL  M V H  AK++VELSK+QD E GD              
Sbjct: 1   KMIQAANGDVTITNDGATILKQMQVLHPAAKMLVELSKAQDIEXGDGTTTVVVLAGSLLD 180

Query: 119 XXXQLLDRGIHPIRIADGYEQAARIAIQHLDKISDKVLVDINNPEPLIQTAKTTLGSKVI 178
              +LL +GIHP  I++ +++AA   ++ LD +     +++++ E L+ +A T+L SKV+
Sbjct: 181 ASAKLLAKGIHPTMISEAFQKAASKCVELLDGMVKP--LELSDRESLLSSASTSLNSKVV 354

Query: 179 NSCHRQMAEIAVNAVLTVAD-MERRDVDFELIKVEGKVGGRLE 220
           +     +A IAV+AVL V D     +VD + IK+  K+GG ++
Sbjct: 355 SQYSSMLAPIAVDAVLKVIDPATATNVDLKDIKIIKKLGGTID 483
>30661
          Length = 380

 Score = 84.7 bits (208), Expect = 8e-17,   Method: Composition-based stats.
 Identities = 47/114 (41%), Positives = 64/114 (56%)
 Frame = +3

Query: 338 GGRIVPRFSELTSEKLGFAGVVQEISFGTTKDKMLVIEKCKNSRAVTIFIRGGNKMIIEE 397
           GG I   F      KLG   +++E+  G  +DK++         A TI +RG  + I++E
Sbjct: 30  GGEITSTFDCPEKTKLGQCDLIEEVMIG--EDKLIKFSGVALGEACTIVLRGATQQILDE 203

Query: 398 AKRSLHDALCVIRNLIRDNRVVYGGGAAEISCALAVSQEADKCPTLEQYAMRAF 451
           A RSLHDALCV+   +++ R VYGGG +E+  A AVSQ A K P  E  AM A 
Sbjct: 204 AXRSLHDALCVLSQTVKETRTVYGGGCSEMLMAEAVSQLAAKTPGKEAIAMEAL 365
>10291
          Length = 1066

 Score = 67.0 bits (162), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 33/49 (67%), Positives = 40/49 (81%)
 Frame = +1

Query: 490 GIDCLHKGSNDMQYQHVIETLIGKKQQISLATQMVRMILKIDDIRKPGE 538
           G+ C  +G+NDM+ Q+VIETL  KKQQI LATQ+VRMILKIDDIR P +
Sbjct: 13  GVGC--RGTNDMKEQNVIETLTAKKQQILLATQLVRMILKIDDIRAPSD 153
>17249
          Length = 909

 Score = 45.4 bits (106), Expect = 6e-05,   Method: Compositional matrix adjust.
 Identities = 29/80 (36%), Positives = 40/80 (50%)
 Frame = +3

Query: 454 ALEVIPMALSENSGMNPIQTMTEVRARQVKESNPALGIDCLHKGSNDMQYQHVIETLIGK 513
           ALEVI   L +N G N I+T+T +RA+  +      GID       DM    + E L  K
Sbjct: 12  ALEVISRTLIQNCGANTIRTLTALRAKHAQGQKNTWGIDGNTGNIVDMAEFGIWEPLSVK 191

Query: 514 KQQISLATQMVRMILKIDDI 533
            Q    A +   ++L+IDDI
Sbjct: 192 LQVYKTACETAILLLRIDDI 251
>09856
          Length = 1154

 Score = 30.4 bits (67), Expect = 1.7,   Method: Compositional matrix adjust.
 Identities = 17/45 (37%), Positives = 23/45 (51%), Gaps = 2/45 (4%)
 Frame = -2

Query: 242 KVVDAKIAILTCPFEPPKPKTKHKLDVMSVEDYKALQK--YEKEK 284
           KV+D+ I I TC F P +    H   + + +DY  L    YEK K
Sbjct: 163 KVMDSFIVIKTCMFFPLQH*NDHNYQLNTTQDYNFLGNITYEKTK 29
>29327
          Length = 2425

 Score = 30.4 bits (67), Expect = 1.8,   Method: Compositional matrix adjust.
 Identities = 16/41 (39%), Positives = 28/41 (68%), Gaps = 1/41 (2%)
 Frame = +1

Query: 494 LHKGS-NDMQYQHVIETLIGKKQQISLATQMVRMILKIDDI 533
           L +G+  ++  ++V++ L+     I+LA++ VR ILKIDDI
Sbjct: 157 LFQGAITNILEENVLQPLLVSTSAITLASETVRSILKIDDI 279
>21277
          Length = 1201

 Score = 28.1 bits (61), Expect = 9.8,   Method: Compositional matrix adjust.
 Identities = 13/48 (27%), Positives = 19/48 (39%)
 Frame = +1

Query: 289 IKQIKETGANLAICQWGFDDEANHLLLQNGLPAVRWVGGPEIELIAIA 336
            K  +  G  +A+C WG     +H       PA+ W   P +   A A
Sbjct: 943 WKCTRWNGEEVAVCSWGSGRAGDHRDHGRARPALMWPSTPSVRTWAGA 1086
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6678359|ref|NP_033414.1| transketolase [Mus musculus]
         (623 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

12789                                                                 823   0.0  
26410                                                                  48   1e-05
33855                                                                  37   0.018
34622                                                                  29   7.1  
>12789
          Length = 2095

 Score =  823 bits (2127), Expect = 0.0,   Method: Compositional matrix adjust.
 Identities = 392/625 (62%), Positives = 482/625 (77%), Gaps = 5/625 (0%)
 Frame = +3

Query: 2   EGYHKPDQQKLQALKDTANRLRISSIQATTAAGSGHPTSCCSAAEIMAVLFFHTMRYKAL 61
           + YH  D +KLQAL+D AN+LRI SI++T+A+ SGHPTSC SAAEIM+VLFFHTM+Y   
Sbjct: 75  DNYHCLDAKKLQALRDIANKLRIHSIESTSASNSGHPTSCSSAAEIMSVLFFHTMKYSIE 254

Query: 62  DPRNPHNDRFVLSKGHAAPILYAVWAEAGFLPEAELLNLRKISSDLDGHPVPKQAFTDVA 121
           +PR P NDRFVLSKGHAAPILYA WAEAG  P A+L NLRKI SDL+GHP P+  F DVA
Sbjct: 255 EPRGPSNDRFVLSKGHAAPILYAAWAEAGLFPTADLKNLRKIDSDLEGHPTPRLNFVDVA 434

Query: 122 TGSLGQGLGAACGMAYTGKYFDKASYRVYCMLGDGEVSEGSVWEAMAFAGIYKLDNLVAI 181
           TGSLGQGL  A GMAYTGKYFDKA YRVYC++GDGE +EGSVWEAMAFA  YKLDNLV +
Sbjct: 435 TGSLGQGLSCAAGMAYTGKYFDKAGYRVYCIIGDGESAEGSVWEAMAFASEYKLDNLVVV 614

Query: 182 FDINRLGQSDPAPLQHQVDIYQKRCEAFGWHTIIVDGHSVEELCKAF---GQAKHQPTAI 238
           FD+NRLGQS    L H +D+Y+ R EAFGW+T +VDGH VE L + F    Q K++PT +
Sbjct: 615 FDVNRLGQSQATSLGHSMDVYKARAEAFGWNTYVVDGHDVEGLSRVFYDASQVKNKPTCV 794

Query: 239 IAKTFKGRGITGIEDKEAWHGKPLPKNMAEQIIQEIYSQVQSKKKILATPPQED--APSV 296
           +AKTFKG  I GI D++ WHGK L  + A+  ++ +  Q+ +K     TPP  D  AP +
Sbjct: 795 LAKTFKGNAIQGISDQDNWHGKAL-GDRADDAVKALTDQLANKGHHGITPPVPDSKAPVI 971

Query: 297 DIANIRMPTPPSYKVGDKIATRKAYGLALAKLGHASDRIIALDGDTKNSTFSELFKKEHP 356
           +  NI +   P+Y +G  +ATR AYG AL K+G  +DR+I+LDGD KNSTF+  FK+ +P
Sbjct: 972 NTTNITLSEXPAYTMGQLVATRAAYGTALVKVGKTNDRVISLDGDVKNSTFASKFKEAYP 1151

Query: 357 DRFIECYIAEQNMVSIAVGCATRDRTVPFCSTFAAFFTRAFDQIRMAAISESNINLCGSH 416
           DRF+EC+IAEQN+V +A+GC TR RTVPF STFAAF +RAFDQIRMAAIS+SN+N CGSH
Sbjct: 1152DRFVECFIAEQNLVGVAIGCETRRRTVPFVSTFAAFLSRAFDQIRMAAISQSNVNFCGSH 1331

Query: 417 CGVSIGEDGPSQMALEDLAMFRSVPMSTVFYPSDGVATEKAVELAANTKGICFIRTSRPE 476
            G+SIGEDGPSQMALED+AMFRS+P  TVFYPSD V+TE+AVELAANT+G+CFIRTSRP 
Sbjct: 1332AGISIGEDGPSQMALEDIAMFRSIPDCTVFYPSDAVSTERAVELAANTRGMCFIRTSRPN 1511

Query: 477 NAIIYSNNEDFQVGQAKVVLKSKDDQVTVIGAGVTLHEALAAAESLKKDKISIRVLDPFT 536
             +IY  +E F VG+AKVV +S  DQVTVIGA VTL EA+ AA+ L    ++IR++DPFT
Sbjct: 1512VPVIYQPSETFTVGKAKVVRQSASDQVTVIGACVTLAEAMKAADELAGSGVNIRIIDPFT 1691

Query: 537 IKPLDRKLILDSARATKGRILTVEDHYYEGGIGEAVSAAVVGEPGVTVTRLAVSQVPRSG 596
           IKPLD   I+ +ARAT GRI+TVEDHY EGGIGEAV +AV     +TV RLAV ++PRSG
Sbjct: 1692IKPLDADTIISNARATSGRIITVEDHYMEGGIGEAVCSAVSECKDITVRRLAVKEIPRSG 1871

Query: 597 KPAELLKMFGIDKDAIVQAVKGLVT 621
           K  ELL+ +GI    IV+AV+ +++
Sbjct: 1872KCGELLERYGISAACIVKAVQQVLS 1946
>26410
          Length = 1216

 Score = 47.8 bits (112), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 63/276 (22%), Positives = 105/276 (38%), Gaps = 22/276 (7%)
 Frame = +1

Query: 350 LFKKEHPDRFIECYIAEQNMVSIAVGCATRDRTVPFCSTFAAFFT-RAFDQIRMAAISES 408
           L+KK    R I+  I E     IAVG A      P C      F+ +A DQ+  +A    
Sbjct: 1   LWKKYGDKRVIDTPITEMGFAGIAVGAAMAGLK-PICEFMTFNFSMQAIDQVINSA--AK 171

Query: 409 NINLCGSHCGVSIGEDGPSQMALEDLA--------MFRSVPMSTVFYPSDGVATEKAVEL 460
              +      V I   GP+  AL   A         + S P   V  P         ++ 
Sbjct: 172 TFYMSAGQVPVPIVFRGPNGAALGVAAQHSQCFAAWYSSCPGLKVLSPYSSEDCRGLLKA 351

Query: 461 AANTKGICFIRTSRP----ENAIIYSN---------NEDFQVGQAKVVLKSKDDQVTVIG 507
           A        IR   P    EN I+Y           + DF     K  ++ +   VT++ 
Sbjct: 352 A--------IRDPNPVVVLENEIMYGTAFDVSDEALSPDFVAPIGKAKIEREGSHVTLVA 507

Query: 508 AGVTLHEALAAAESLKKDKISIRVLDPFTIKPLDRKLILDSARATKGRILTVEDHYYEGG 567
             + +   + AA+ L    +   +++  +++P+D + I+ S   T   ++TVE  + + G
Sbjct: 508 HSIGVGRCVEAAKELAGQGVECEIVNLRSLRPMDDETIIKSVMKTN-HLVTVEGGWPQCG 684

Query: 568 IGEAVSAAVVGEPGVTVTRLAVSQVPRSGKPAELLK 603
           IG  ++A ++  P        V +V  +  P    K
Sbjct: 685 IGSEITARIMESPAFNYLDAPVYRVTGADVPMPYTK 792
>33855
          Length = 600

 Score = 37.4 bits (85), Expect = 0.018,   Method: Composition-based stats.
 Identities = 34/103 (33%), Positives = 48/103 (46%), Gaps = 7/103 (6%)
 Frame = +1

Query: 149 VYCMLGDGEVSEGSVWEAMAFAGIYKLDNLVAIFDINR-LGQSDPAPLQHQVDIYQKRCE 207
           V C  GDG  SEG    A+ FA +  LD  +  F  N     S P   Q++ D    R  
Sbjct: 229 VICYFGDGAASEGDAHAALNFAAV--LDCPIIFFCRNNGYAISTPTKDQYRGDGIAARGP 402

Query: 208 AFGWHTIIVDGH---SVEELCKAFGQ---AKHQPTAIIAKTFK 244
            +G  TI VDG+   +V    KA  Q   ++++P  I A T++
Sbjct: 403 GYGISTIRVDGNDPFAVYNATKAGRQICLSQNRPVLIEAMTYR 531
>34622
          Length = 477

 Score = 28.9 bits (63), Expect = 7.1,   Method: Composition-based stats.
 Identities = 14/31 (45%), Positives = 16/31 (51%)
 Frame = +2

Query: 103 ISSDLDGHPVPKQAFTDVATGSLGQGLGAAC 133
           I  D+DGHPV  Q+  DV    L  GL   C
Sbjct: 206 IGHDVDGHPVTLQSLKDVEVHGLVVGLRRDC 298
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6678467|ref|NP_033473.1| tubulin, alpha 4 [Mus
musculus]
         (448 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

00276                                                                 688   0.0  
12457                                                                 449   e-131
06360                                                                 330   6e-91
03702                                                                 278   3e-75
17215                                                                 254   7e-68
16482                                                                 213   1e-55
13181                                                                 187   5e-48
04882                                                                 176   2e-44
05902                                                                 137   7e-33
25015                                                                 114   1e-25
39157                                                                  91   6e-19
28905                                                                  91   8e-19
31457                                                                  88   6e-18
13964                                                                  33   0.17 
26569                                                                  32   0.55 
06591                                                                  30   2.7  
18555                                                                  28   6.1  
>00276
          Length = 1330

 Score =  688 bits (1776), Expect = 0.0,   Method: Compositional matrix adjust.
 Identities = 328/360 (91%), Positives = 338/360 (93%)
 Frame = -3

Query: 80   NGPYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDPVLDRIRKLSDQCTGLQGFLVFH 139
             G YRQL  PEQL+TGKEDAANNYARGHYTIGKE++D VLDRIRKL+DQCTGLQGFL+FH
Sbjct: 1328 TGTYRQL-SPEQLVTGKEDAANNYARGHYTIGKELVDLVLDRIRKLADQCTGLQGFLIFH 1152

Query: 140  XXXXXXXXXXXXLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSD 199
                        L MERLSVDYGKKSKLEF IYPAPQVSTAVVEPYNSILTTHTTLEHSD
Sbjct: 1151 SFGGGTGSGFTSLXMERLSVDYGKKSKLEFXIYPAPQVSTAVVEPYNSILTTHTTLEHSD 972

Query: 200  CAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNL 259
            CAFMVDNEAIYDICRRNLDIERPTYTNLNRLI QIVSSITASLRFDGALNVDLTEFQTNL
Sbjct: 971  CAFMVDNEAIYDICRRNLDIERPTYTNLNRLIXQIVSSITASLRFDGALNVDLTEFQTNL 792

Query: 260  VPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLY 319
            VPYPRIHFPLATYAPVISAEKAYHEQL VAEITNACFEPANQ+VKCDPRHGKYMACC+LY
Sbjct: 791  VPYPRIHFPLATYAPVISAEKAYHEQLXVAEITNACFEPANQLVKCDPRHGKYMACCMLY 612

Query: 320  RGDVVPKDVNAAIAAIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLS 379
            RGDVVPKDVNAAIA IKTKR+IQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLS
Sbjct: 611  RGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLS 432

Query: 380  NTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGIDS 439
            NTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEARED+AALEKDYEEVG+DS
Sbjct: 431  NTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVGVDS 252
>12457
          Length = 781

 Score =  449 bits (1155), Expect(2) = e-131,   Method: Compositional matrix adjust.
 Identities = 214/239 (89%), Positives = 222/239 (92%)
 Frame = -1

Query: 67  FVDLEPTVIDEIRNGPYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDPVLDRIRKLS 126
            VDLEPTV+DE+R G YRQLFHPEQL+TGKEDAANNYARGHYTIGKEI+D VLDRIRKL+
Sbjct: 718 LVDLEPTVVDEVRTGTYRQLFHPEQLVTGKEDAANNYARGHYTIGKEIVDLVLDRIRKLA 539

Query: 127 DQCTGLQGFLVFHXXXXXXXXXXXXLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYN 186
           DQCTGLQGFL+FH            LLMERLSVDYGKKSKLEF+IYPAPQVSTAVVEPYN
Sbjct: 538 DQCTGLQGFLIFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFAIYPAPQVSTAVVEPYN 359

Query: 187 SILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDG 246
           SILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLI QIVSSITASLRFDG
Sbjct: 358 SILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLRFDG 179

Query: 247 ALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKC 305
           ALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQL+VAEITNACFEPANQMVKC
Sbjct: 178 ALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLTVAEITNACFEPANQMVKC 2

 Score = 37.4 bits (85), Expect(2) = e-131,   Method: Compositional matrix adjust.
 Identities = 19/28 (67%), Positives = 19/28 (67%)
 Frame = -2

Query: 45  GDDSFTTFFCETGAGKHVPRAVFVDLEP 72
           GDDSFT    ETGAGKHVPRAV     P
Sbjct: 780 GDDSFTPL-SETGAGKHVPRAVSSXXSP 700
>06360
          Length = 1896

 Score =  330 bits (847), Expect = 6e-91,   Method: Compositional matrix adjust.
 Identities = 154/178 (86%), Positives = 161/178 (90%)
 Frame = -1

Query: 1    MRECISVHVGQAGVQMGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFTTFFCETGAGK 60
            MRECISVHVGQAGVQMGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSF TFF ETGAGK
Sbjct: 1710 MRECISVHVGQAGVQMGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGK 1531

Query: 61   HVPRAVFVDLEPTVIDEIRNGPYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDPVLD 120
            HVPRAVFVDLEPTV+DE+R G YRQLFHPEQL+TGKEDAANNYARGHYTIGKEI+D VLD
Sbjct: 1530 HVPRAVFVDLEPTVVDEVRTGTYRQLFHPEQLVTGKEDAANNYARGHYTIGKEIVDLVLD 1351

Query: 121  RIRKLSDQCTGLQGFLVFHXXXXXXXXXXXXLLMERLSVDYGKKSKLEFSIYPAPQVS 178
            RIRKL+DQCTGLQGFL+FH            LLMERLSVDYGKKSKLEF+IYPAPQVS
Sbjct: 1350 RIRKLADQCTGLQGFLIFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFAIYPAPQVS 1177
>03702
          Length = 1932

 Score =  278 bits (711), Expect = 3e-75,   Method: Compositional matrix adjust.
 Identities = 138/155 (89%), Positives = 142/155 (91%)
 Frame = +1

Query: 153  LMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDI 212
            L ERLSVDYGKKSKLEF+IYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDI
Sbjct: 1453 L*ERLSVDYGKKSKLEFAIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDI 1632

Query: 213  CRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATY 272
            CRRNLDIERP YTNLNRLI QIVSSITASLRFDGALNVDLTEFQTNLVP P    P    
Sbjct: 1633 CRRNLDIERPXYTNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNLVPTPH-PLPPGHL 1809

Query: 273  APVISAEKAYHEQLSVAEITNACFEPANQMVKCDP 307
             PVISAEKAYHEQL+VAE+TNACFEPANQ+VKCDP
Sbjct: 1810 CPVISAEKAYHEQLTVAEVTNACFEPANQLVKCDP 1914
>17215
          Length = 632

 Score =  254 bits (648), Expect = 7e-68,   Method: Compositional matrix adjust.
 Identities = 118/123 (95%), Positives = 122/123 (99%)
 Frame = +3

Query: 317 LLYRGDVVPKDVNAAIAAIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVC 376
           +LYRGDVVPKDVNAAIA IKTKR+IQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVC
Sbjct: 3   MLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVC 182

Query: 377 MLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVG 436
           MLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEARED+AALEKDYEEVG
Sbjct: 183 MLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVG 362

Query: 437 IDS 439
           +DS
Sbjct: 363 VDS 371
>16482
          Length = 837

 Score =  213 bits (542), Expect = 1e-55,   Method: Compositional matrix adjust.
 Identities = 103/248 (41%), Positives = 149/248 (60%)
 Frame = +1

Query: 1   MRECISVHVGQAGVQMGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFTTFFCETGAGK 60
           MRE + +  GQ G Q+G   WE+   EHGI P G    D  +    +    ++ E   GK
Sbjct: 100 MREIVHMQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQ--LERINVYYNEATGGK 273

Query: 61  HVPRAVFVDLEPTVIDEIRNGPYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDPVLD 120
           +VPRAV VDLEP  +D +R+GP+ Q+F P+  + G+  A NN+A+GHYT G E++D VLD
Sbjct: 274 YVPRAVLVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLD 453

Query: 121 RIRKLSDQCTGLQGFLVFHXXXXXXXXXXXXLLMERLSVDYGKKSKLEFSIYPAPQVSTA 180
            +RK ++ C  LQGF + H            LL+ ++  +Y  +    FS+ P+P+VS  
Sbjct: 454 VVRKEAESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVVPSPKVSDT 633

Query: 181 VVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITA 240
           VVEPYN+ L+ H  +E++D  + +DNEA+YDIC R L +  PTY +LN L+S  +S +T 
Sbjct: 634 VVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTT 813

Query: 241 SLRFDGAL 248
            LRF G L
Sbjct: 814 CLRFPGQL 837
>13181
          Length = 1092

 Score =  187 bits (476), Expect = 5e-48,   Method: Compositional matrix adjust.
 Identities = 85/225 (37%), Positives = 131/225 (58%)
 Frame = -3

Query: 210  YDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPL 269
            YDIC R L +  PTY +LN L+S  +S +T  LRF G LN DL +   N+VP+PR+HF +
Sbjct: 1090 YDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFM 911

Query: 270  ATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVN 329
              +AP+ S     +  L+V E+T   F+  N M  CDPRHG+Y+    ++RG +  K+V+
Sbjct: 910  PGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAMFRGRMSMKEVD 731

Query: 330  AAIAAIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWA 389
              +  ++ K S  FV+W P   K  +   PP          ++ +   + N+TAI E + 
Sbjct: 730  EQMLNVQNKNSSYFVEWIPNNVKTAVCDIPP--------RGLKMSATFVGNSTAIQELFK 575

Query: 390  RLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEE 434
            R+  +F  M+ ++AF+HWY GEGM+E EF+EA  +M  L  +Y++
Sbjct: 574  RISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQ 440
>04882
          Length = 1136

 Score =  176 bits (446), Expect = 2e-44,   Method: Compositional matrix adjust.
 Identities = 79/216 (36%), Positives = 125/216 (57%)
 Frame = +2

Query: 219 IERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISA 278
           +  PTY +LN L+S  +S +T  LRF G LN DL +   N+VP+PR+HF +  +AP+ S 
Sbjct: 314 VHTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSR 493

Query: 279 EKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIAAIKTK 338
               +  L+V E+T   F+  N M  CDPRHG+Y+    ++RG +  K+V+  +  ++ K
Sbjct: 494 GSQQYRALTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNK 673

Query: 339 RSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLM 398
            S  FV+W P   K  +   PP          ++ +   + N+TAI E + R+  +F  M
Sbjct: 674 NSSYFVEWIPNNVKTAVCDIPPR--------GLKMSATFIGNSTAIQELFKRISEQFTAM 829

Query: 399 YAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEE 434
           + ++AF+HWY GEGM+E EF+EA  +M  L  +Y++
Sbjct: 830 FRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQ 937
>05902
          Length = 1127

 Score =  137 bits (346), Expect = 7e-33,   Method: Compositional matrix adjust.
 Identities = 82/290 (28%), Positives = 160/290 (55%), Gaps = 9/290 (3%)
 Frame = +2

Query: 153 LMERLSVDYGKKSKLEFSIYP-APQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYD 211
           L+E+L+  + KK    +S++P   ++S  VV+PYNS+LT     +++DC  ++DN A+  
Sbjct: 65  LLEKLNDRFPKKLIQTYSVFPNVDEISDVVVQPYNSLLTLKRLTQNADCVVVLDNTALNR 244

Query: 212 ICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLAT 271
           I    L I+ PT+  +N+L+S ++S+ T +LR+ G +N DL     +L+P PR+HF +  
Sbjct: 245 IAADRLHIDTPTFAQVNQLVSTVMSTSTTTLRYPGYMNNDLIGLIASLIPTPRLHFLMTG 424

Query: 272 YAPVIS-AEKAYHEQLSVAEITNACFEPANQMVKCDPRHGK----YMACCLLYRGDVVPK 326
           Y P+ + ++ A   + +V ++     +P N MV   P H +    Y++   + +G+V P 
Sbjct: 425 YTPLTTDSQVANVRKTTVLDVMRRLLQPKNMMVST-PVHRQANHCYISILNIIQGEVDPT 601

Query: 327 DVNAAIAAIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAE 386
            V+ ++  I+ ++  QF+ W P   +V ++ + P V     ++ +     ML+N T+I+ 
Sbjct: 602 QVHKSLQRIRERKLAQFIPWGPASIQVALSRKSPYVQTAHRVSGL-----MLANHTSISH 766

Query: 387 AWARLDHKFDLMYAKRAFVHWYVGEGMEE---GEFSEAREDMAALEKDYE 433
            + R+  ++D +  + AF+  +  E + +    EF  +RE +  L  +Y+
Sbjct: 767 LFERILRQYDKLRKREAFMDQFKKEAIFKDNLDEFDNSREALQLLVDEYQ 916
>25015
          Length = 458

 Score =  114 bits (284), Expect = 1e-25,   Method: Compositional matrix adjust.
 Identities = 52/119 (43%), Positives = 74/119 (62%)
 Frame = -3

Query: 21  WELYCLEHGIQPDGQMPSDKTIGGGDDSFTTFFCETGAGKHVPRAVFVDLEPTVIDEIRN 80
           WE+   EHGI P G    D  +    +    ++ E   GK+VPRAV VDLEP  +D +R+
Sbjct: 360 WEVISDEHGIDPTGTYHGDSDLQ--LERINVYYNEATGGKYVPRAVLVDLEPGTMDSVRS 187

Query: 81  GPYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDPVLDRIRKLSDQCTGLQGFLVFH 139
           GP+ Q+F P+  + G+  A NN+A+GHYT G E++D VLD +RK ++ C  LQGF + H
Sbjct: 186 GPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEAESCDCLQGFQLTH 10
>39157
          Length = 488

 Score = 91.3 bits (225), Expect = 6e-19,   Method: Compositional matrix adjust.
 Identities = 49/127 (38%), Positives = 72/127 (56%), Gaps = 3/127 (2%)
 Frame = -1

Query: 1   MRECISVHVGQAGVQMGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFTTFFCETGAGK 60
           MRE + +  GQ G Q+G   WE+   EHGI P G    D  +    +    ++ E   GK
Sbjct: 443 MREIVHLQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQ--LERINVYYNEATGGK 270

Query: 61  HVPRAVFVDLEPTVIDEIRNG-PYR-QLFHPEQLITGKEDAANNYARGHYTI-GKEIIDP 117
           +VPRAV VDLEP  +D +R+G P+  ++F P+  + G+  A NN+ +   T  G E++D 
Sbjct: 269 YVPRAVLVDLEPGTMDSVRSGSPFGPKIFRPDNFVFGQSGAGNNWGQKDTTQRGAELVDS 90

Query: 118 VLDRIRK 124
           VLD +RK
Sbjct: 89  VLDVVRK 69
>28905
          Length = 425

 Score = 91.3 bits (225), Expect = 8e-19,   Method: Composition-based stats.
 Identities = 37/103 (35%), Positives = 59/103 (57%)
 Frame = -1

Query: 258 NLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCL 317
           N+VP+PR+HF +  +AP+ S     +  L+V E+T   F+  N M  CDPRHG+Y+    
Sbjct: 380 NMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAA 201

Query: 318 LYRGDVVPKDVNAAIAAIKTKRSIQFVDWCPTGFKVGINYQPP 360
           ++RG +  K+V+  +  ++ K S  FV+W P   K  +   PP
Sbjct: 200 MFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPP 72
>31457
          Length = 1530

 Score = 88.2 bits (217), Expect = 6e-18,   Method: Compositional matrix adjust.
 Identities = 40/124 (32%), Positives = 69/124 (55%)
 Frame = +3

Query: 311 KYMACCLLYRGDVVPKDVNAAIAAIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAK 370
           KY+    ++RG +  K+V+  +  ++ K S  FV+W P   K  +   PP          
Sbjct: 234 KYLTVAAMFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPR--------G 389

Query: 371 VQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEK 430
           ++ +   + N+TAI E + R+  +F  M+ ++AF+HWY GEGM+E EF+EA  +M  L  
Sbjct: 390 LKMSSTFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS 569

Query: 431 DYEE 434
           +Y++
Sbjct: 570 EYQQ 581
>13964
          Length = 528

 Score = 33.5 bits (75), Expect = 0.17,   Method: Compositional matrix adjust.
 Identities = 14/16 (87%), Positives = 16/16 (100%)
 Frame = +2

Query: 424 DMAALEKDYEEVGIDS 439
           D+AALEKDYEEVG+DS
Sbjct: 230 DLAALEKDYEEVGVDS 277
>26569
          Length = 1180

 Score = 32.0 bits (71), Expect = 0.55,   Method: Compositional matrix adjust.
 Identities = 20/62 (32%), Positives = 26/62 (41%)
 Frame = +1

Query: 373 RAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDY 432
           R V   +N  A +E W +   KF    A+    HW  G+G E  + S AR     L  D 
Sbjct: 481 RGVNRPANYCAGSETWTQRKKKFSNWNAR----HWKRGKGKERRKISLARAGGVGLAVDT 648

Query: 433 EE 434
            E
Sbjct: 649 SE 654
>06591
          Length = 978

 Score = 29.6 bits (65), Expect = 2.7,   Method: Compositional matrix adjust.
 Identities = 19/57 (33%), Positives = 24/57 (42%)
 Frame = -2

Query: 320 RGDVVPKDVNAAIAAIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVC 376
           RG  VP +         T  S    DWCP G + G+ YQ  T     D+A  Q  +C
Sbjct: 767 RGSCVPSE---------TSLSTPVTDWCPQGDQPGVVYQNLTCA---DVATSQPWLC 633
>18555
          Length = 596

 Score = 28.5 bits (62), Expect = 6.1,   Method: Compositional matrix adjust.
 Identities = 16/48 (33%), Positives = 26/48 (54%)
 Frame = -1

Query: 232 SQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAE 279
           +QI S    S  +  AL +D   F  + +  P+++FPL+   PV+SA 
Sbjct: 344 NQIFS*S*KSFCYSLALTIDKKHFNKDRLLKPKVNFPLS*GQPVLSAS 201
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6681273|ref|NP_031932.1| eukaryotic translation
elongation factor 1 alpha 2 [Mus musculus]
         (463 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

15991                                                                 568   0.0  
00709                                                                 462   e-130
22349                                                                 143   1e-34
16686                                                                  75   4e-14
15617                                                                  51   1e-06
04430                                                                  28   0.032
31464                                                                  36   0.035
35135                                                                  35   0.056
14064                                                                  31   0.90 
>15991
          Length = 1629

 Score =  568 bits (1464), Expect(3) = 0.0,   Method: Compositional matrix adjust.
 Identities = 276/336 (82%), Positives = 296/336 (88%)
 Frame = -3

Query: 44   KEAAEMGKGSFKYAWVLDKLKAERERGITIDISLWKFETTKYYITIIDAPGHRDFIKNMI 103
            +EAAEMGKGSFKYAWVLDKLKAERERGITIDI+LWKFET KYY+TIIDAPGHRDFIKNMI
Sbjct: 1546 EEAAEMGKGSFKYAWVLDKLKAERERGITIDIALWKFETDKYYVTIIDAPGHRDFIKNMI 1367

Query: 104  TGTSQADCAVLIVAAGVGEFEAGISKNGQTREHALLAYTLGVKQLIVGVNKMDSTEPAYS 163
            TGTSQADCAVL+VAAG GEFEAGISK+GQTREHALLAYTLGVKQLIV VNKMDSTEP YS
Sbjct: 1366 TGTSQADCAVLVVAAGKGEFEAGISKDGQTREHALLAYTLGVKQLIVAVNKMDSTEPPYS 1187

Query: 164  EKRYDEIVKEVSAYIKKIGYNPATVPFVPISGWHGDNMLEPSPNMPWFKGWKVERKEGNA 223
              R++EI KEVS YIKKIGYNP TV FVPISGW GDNM+E S  +     WK+ERKEG A
Sbjct: 1186 MDRFEEIKKEVSTYIKKIGYNPNTVAFVPISGWVGDNMMEASTKI--VHKWKIERKEGKA 1013

Query: 224  SGVSLLEALDTILPPTRPTDKPLRLPLQDVYKIGGIGTVPVGRVETGILRPGMVVTFAPV 283
             G +L EALD ILPPTRPTDK LRLPLQDVYKIGGIGTVPVGRVETGIL+PG VVTFAP 
Sbjct: 1012 EGETLKEALDAILPPTRPTDKALRLPLQDVYKIGGIGTVPVGRVETGILKPGTVVTFAPG 833

Query: 284  NITTEVKSVEMHHEALSEALPGDNVGFNVKNVSVKDIRRGNVCGDSKADPPQEAAQFTSQ 343
             +TTEVKSVEMHHE L EALPGDNVGFNVKNVSVKDIRRGNV GDSK DPP+ A  F +Q
Sbjct: 832  GLTTEVKSVEMHHEQLQEALPGDNVGFNVKNVSVKDIRRGNVAGDSKNDPPKGAKNFYAQ 653

Query: 344  VIILNHPGQISAGYSPVIDCHTAHIACKFAELKEKI 379
            VIILNHPG I AGY+PV+DCHTAHIACKF EL+ ++
Sbjct: 652  VIILNHPGMIHAGYAPVLDCHTAHIACKFEELEREV 545

 Score =  125 bits (314), Expect(3) = 0.0,   Method: Compositional matrix adjust.
 Identities = 61/78 (78%), Positives = 67/78 (85%)
 Frame = -1

Query: 375 LKEKIDRRSGKKLEDNPKSLKSGDAAIVEMVPGKPMCVESFSQYPPLGRFAVRDMRQTVA 434
           LKEK D RSGKKLEDNPK +KSGDAA+V +VP KPMCVE+F  YPPLGRFAVRDM+QTVA
Sbjct: 558 LKEKCDXRSGKKLEDNPKCVKSGDAAMVTLVPSKPMCVEAFVDYPPLGRFAVRDMKQTVA 379

Query: 435 VGVIKNVEKKSGGAGKVT 452
           VGVIK+VEK    AGKVT
Sbjct: 378 VGVIKSVEKVE-AAGKVT 328

 Score = 54.3 bits (129), Expect(3) = 0.0,   Method: Compositional matrix adjust.
 Identities = 24/32 (75%), Positives = 26/32 (81%)
 Frame = -2

Query: 17   DSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAE 48
            DSGKSTTTGHLIYKCGGIDKR IEK  +   +
Sbjct: 1625 DSGKSTTTGHLIYKCGGIDKRVIEKLRRSCRD 1530
>00709
          Length = 1076

 Score =  462 bits (1188), Expect = e-130,   Method: Compositional matrix adjust.
 Identities = 222/261 (85%), Positives = 237/261 (90%), Gaps = 4/261 (1%)
 Frame = -2

Query: 1   MGKEKTHINIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAEMGKGSFKYAWVL 60
           MGKEK HINIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEA EMGKGSFKYAWVL
Sbjct: 907 MGKEKVHINIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAQEMGKGSFKYAWVL 728

Query: 61  DKLKAERERGITIDISLWKFETTKYYITIIDAPGHRDFIKNMITGTSQADCAVLIVAAGV 120
           DKLKAERERGITIDI+LWKFETTKYY+TIIDAPGHRDFIKNMITGTSQADCAVLIVA+G 
Sbjct: 727 DKLKAERERGITIDIALWKFETTKYYVTIIDAPGHRDFIKNMITGTSQADCAVLIVASGT 548

Query: 121 GEFEAGISKNGQTREHALLAYTLGVKQLIVGVNKMDSTEPAYSEKRYDEIVKEVSAYIKK 180
           GEFEAGISK GQTREHALLAYTLGVKQLI+GVNKMDST PAYSE R++EI KEVS YIKK
Sbjct: 547 GEFEAGISKEGQTREHALLAYTLGVKQLIIGVNKMDSTSPAYSETRFNEIQKEVSGYIKK 368

Query: 181 IGYNPATVPFVPISGWHGDNMLEPSPNMPWFKGWKVERKEGN----ASGVSLLEALDTIL 236
           IG+NP  V FVPISG+HGDNM+  S  M W+KGW++ERKEG     ASG +L +ALD+IL
Sbjct: 367 IGFNPKAVAFVPISGFHGDNMIXESEKMGWYKGWEIERKEGTKEVKASGKTLFDALDSIL 188

Query: 237 PPTRPTDKPLRLPLQDVYKIG 257
           PPTRPT KPLRLPLQDVYKIG
Sbjct: 187 PPTRPTGKPLRLPLQDVYKIG 125

 Score = 53.9 bits (128), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 28/46 (60%), Positives = 32/46 (69%)
 Frame = -3

Query: 237 PPTRPTDKPLRLPLQDVYKIGGIGTVPVGRVETGILRPGMVVTFAP 282
           PP  P       P +   ++ GIGTVPVGRVETGIL+PGMVVTFAP
Sbjct: 186 PPLVPLASLCVCPCRMSTRLEGIGTVPVGRVETGILKPGMVVTFAP 49
>22349
          Length = 662

 Score =  143 bits (361), Expect = 1e-34,   Method: Compositional matrix adjust.
 Identities = 71/153 (46%), Positives = 101/153 (66%), Gaps = 1/153 (0%)
 Frame = -2

Query: 5   KTHINIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAEMGKGSFKYAWVLDKLK 64
           K HIN+V IGHVD+GKST  GHL+Y  G +DKRT+EK+E+EA E  + ++  +W LD   
Sbjct: 499 KDHINVVFIGHVDAGKSTIGGHLLYLTGMVDKRTLEKYEREAKEKNRETWYLSWALDTNN 320

Query: 65  AERERGITIDISLWKFETTKYYITIIDAPGHRDFIKNMITGTSQADCAVLIVAAGVGEF- 123
            ERE+G T+++    FET   + T++DAPGH+ F+ NMI G SQAD A+L+++A  GEF 
Sbjct: 319 EEREKGKTVEVGRAFFETELKHFTVLDAPGHKSFVPNMICGASQADLAILVISARRGEF* 140

Query: 124 EAGISKNGQTREHALLAYTLGVKQLIVGVNKMD 156
           +  +S+  +           GV+ LIV +NKMD
Sbjct: 139 DWFLSEEARHVSMPCW*RRQGVRHLIVLINKMD 41
>16686
          Length = 689

 Score = 75.5 bits (184), Expect = 4e-14,   Method: Compositional matrix adjust.
 Identities = 44/153 (28%), Positives = 81/153 (52%)
 Frame = -2

Query: 289 VKSVEMHHEALSEALPGDNVGFNVKNVSVKDIRRGNVCGDSKADPPQEAAQFTSQVIILN 348
           VK+V +   +   A  GD+V F++ N+ +  +  G V  D  + P + A +  ++V++ N
Sbjct: 649 VKNVTVDDLSSQLAFAGDHVTFSLTNIDMTSVNVGFVLCDPMS-PTKCAIRIRAKVVLFN 473

Query: 349 HPGQISAGYSPVIDCHTAHIACKFAELKEKIDRRSGKKLEDNPKSLKSGDAAIVEMVPGK 408
               I+ G+  V      +    F  L   I++ +G  +++ PK L    +AIVE+   +
Sbjct: 472 LDLPITRGFPVVFHXQCVNEPAVFKRLVATINKSTGDIVKNRPKCLTKNSSAIVELEFER 293

Query: 409 PMCVESFSQYPPLGRFAVRDMRQTVAVGVIKNV 441
            +CVE +S+Y  LGRF +R+   T+A G+I+ +
Sbjct: 292 SVCVELYSEYRDLGRFMLRNSGHTIAAGMIEEI 194
>15617
          Length = 595

 Score = 50.8 bits (120), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 45/133 (33%), Positives = 61/133 (45%), Gaps = 18/133 (13%)
 Frame = -3

Query: 2   GKEKTHINIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAEMGKGSFKYAWVLD 61
           G++K   N+ VI HVD GKST T  L+ K G I           +A+ G+  F      D
Sbjct: 449 GQQKNIRNMSVIAHVDHGKSTLTDSLVSKAGII----------ASAKAGETRFT-----D 315

Query: 62  KLKAERERGITID---ISLW---KFETTKY------------YITIIDAPGHRDFIKNMI 103
             K E+ER ITI    ISL+   K +  KY             I +ID+PGH DF   + 
Sbjct: 314 TRKDEQERCITIKSTAISLYYELKKDDMKYIKQDYDQDNNAFLINLIDSPGHVDFSSEVT 135

Query: 104 TGTSQADCAVLIV 116
                 D A+++V
Sbjct: 134 AALRVTDGALVVV 96
>04430
          Length = 2037

 Score = 28.5 bits (62), Expect(2) = 0.032,   Method: Compositional matrix adjust.
 Identities = 13/13 (100%), Positives = 13/13 (100%)
 Frame = -2

Query: 258  GIGTVPVGRVETG 270
            GIGTVPVGRVETG
Sbjct: 2027 GIGTVPVGRVETG 1989

 Score = 26.2 bits (56), Expect(2) = 0.032,   Method: Compositional matrix adjust.
 Identities = 13/22 (59%), Positives = 16/22 (72%)
 Frame = -1

Query: 270  GILRPGMVVTFAPVNITTEVKS 291
            GIL+PGMVVT  P  ++TEV  
Sbjct: 1992 GILKPGMVVTL-PQPVSTEVSC 1930
>31464
          Length = 946

 Score = 35.8 bits (81), Expect = 0.035,   Method: Compositional matrix adjust.
 Identities = 23/89 (25%), Positives = 36/89 (40%)
 Frame = +1

Query: 238 PTRPTDKPLRLPLQDVYKIGGIGTVPVGRVETGILRPGMVVTFAPVNITTEVKSVEMHHE 297
           P R  D P    +   + +   GTV  G   +G +     V    + +  +VKS++M   
Sbjct: 259 PRRNPDGPFIFSVDHCFSLRXQGTVLTGTAISGSVAVNDTVEIPAMKVQKKVKSMQMFRN 438

Query: 298 ALSEALPGDNVGFNVKNVSVKDIRRGNVC 326
            +   + GD  G  V     K + RG VC
Sbjct: 439 PVDRLVQGDRAGICVTQFDPKLLERGLVC 525
>35135
          Length = 660

 Score = 35.0 bits (79), Expect = 0.056,   Method: Compositional matrix adjust.
 Identities = 13/24 (54%), Positives = 17/24 (70%)
 Frame = +1

Query: 204 PSPNMPWFKGWKVERKEGNASGVS 227
           PSP  PWFK W +E+ + N +GVS
Sbjct: 208 PSPENPWFKEWYMEKHQCNLAGVS 279
>14064
          Length = 1723

 Score = 31.2 bits (69), Expect = 0.90,   Method: Compositional matrix adjust.
 Identities = 21/66 (31%), Positives = 33/66 (50%), Gaps = 2/66 (3%)
 Frame = +2

Query: 81  ETTKYYITIIDAPGHRDFIKNMITGTSQA--DCAVLIVAAGVGEFEAGISKNGQTREHAL 138
           +++   IT+ID  GH  +++  I G +    D A+L+V+A  G         G T+EH  
Sbjct: 122 QSSSKLITLIDLAGHHRYLRTTIVGLTGNCPDFAMLVVSATSGIV-------GMTKEHLG 280

Query: 139 LAYTLG 144
            A  LG
Sbjct: 281 YALALG 298
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6754254|ref|NP_034610.1| heat shock protein 1, alpha
[Mus musculus]
         (733 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

01628                                                                 682   0.0  
15623                                                                 323   e-101
11278                                                                 221   7e-58
27487                                                                 154   2e-37
25874                                                                  81   1e-15
>01628
          Length = 2109

 Score =  682 bits (1761), Expect = 0.0,   Method: Compositional matrix adjust.
 Identities = 330/444 (74%), Positives = 381/444 (85%), Gaps = 1/444 (0%)
 Frame = -3

Query: 291  LNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEEHLAVKHFSVEGQLEFRALLFVPRRAPF 350
            LNKTKP+WTRNPDDIT EEY EFYKSLTNDWE+HLAVKHFSVEGQLEFRALLF+P+RAPF
Sbjct: 1951 LNKTKPLWTRNPDDITAEEYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPKRAPF 1772

Query: 351  DLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKIL 410
            D+FEN+KKKNNIKLYVRRVFIMDNCE++IPEYLNF++GVVDSEDLPLNISREMLQQSKIL
Sbjct: 1771 DMFENKKKKNNIKLYVRRVFIMDNCEDIIPEYLNFVKGVVDSEDLPLNISREMLQQSKIL 1592

Query: 411  KVIRKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSA 470
            KVIRKNLVKKC+EL  +LAEDK+NY KFYEQF+KN+KLGIHEDS NRKK+S+ LRY++S 
Sbjct: 1591 KVIRKNLVKKCMELIDDLAEDKDNYNKFYEQFAKNLKLGIHEDSTNRKKISDFLRYHSSQ 1412

Query: 471  SGDEMVSLKDYCTRMKENQKHIYFITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYC 530
            S DEMV+ K+Y +RMK+NQK IY+ITGET++ V NSAFVER++K G EV+YM++PIDEYC
Sbjct: 1411 SADEMVTFKEYVSRMKDNQKDIYYITGETREAVQNSAFVERVKKRGFEVLYMVDPIDEYC 1232

Query: 531  VQQLKEFEGKTLVSVTXXXXXXXXXXXXXXXXXXXXXXXXNLCKIMKDILEKKVEKVVVS 590
            VQQLKE++GK LV VT                         LCK MK+IL+KKVEKV VS
Sbjct: 1231 VQQLKEYDGKNLVCVTKEGLELPEDEAEKKKFEEAKAEFEGLCKAMKEILDKKVEKVTVS 1052

Query: 591  NRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQK 650
             RLV+SPCCIVTS YGW+ANMERIMKAQALRD STMGYMAAKKH EINPDH I++TL+ K
Sbjct: 1051 QRLVSSPCCIVTSQYGWSANMERIMKAQALRDTSTMGYMAAKKHFEINPDHPIVKTLKVK 872

Query: 651  AEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTVDDTS 710
             +ADKNDKSVKDL +LL+ETALLSSGF+LEDP +HANRI+RM+KLGLGIDEDD T  + +
Sbjct: 871  CDADKNDKSVKDLCMLLFETALLSSGFTLEDPTSHANRIHRMVKLGLGIDEDDST-PEAA 695

Query: 711  AAVTEEMPPLEGD-DDTSRMEEVD 733
             A  ++MPPLEGD DD SRMEEVD
Sbjct: 694  EAPADDMPPLEGDEDDASRMEEVD 623
>15623
          Length = 2811

 Score =  323 bits (827), Expect(2) = e-101,   Method: Compositional matrix adjust.
 Identities = 151/186 (81%), Positives = 170/186 (91%)
 Frame = -1

Query: 41  KEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPSKQDRTLTIVDTGIGMTK 100
           +EIFLRELISNSSDALDKIRYESLTDPSKLD+GK+LHI ++P K+ +TLTI D+GIGMTK
Sbjct: 585 QEIFLRELISNSSDALDKIRYESLTDPSKLDAGKDLHIRIVPDKERKTLTIEDSGIGMTK 406

Query: 101 ADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQY 160
           ADL+NNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVA++V V +K+NDDEQY
Sbjct: 405 ADLVNNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVADRVVVESKNNDDEQY 226

Query: 161 AWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITL 220
            WESSAGGSFT+   TG PMGRGT++ L +KEDQ EYLEERRIKE++KKHSQFIGYPI L
Sbjct: 225 TWESSAGGSFTIAAPTGTPMGRGTRITLFMKEDQQEYLEERRIKEVIKKHSQFIGYPIKL 46

Query: 221 FVEKER 226
            VEKER
Sbjct: 45  LVEKER 28

 Score = 63.5 bits (153), Expect(2) = e-101,   Method: Compositional matrix adjust.
 Identities = 34/41 (82%), Positives = 34/41 (82%)
 Frame = -2

Query: 1   MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNK 41
           MPEET      MEE EVETFAFQAEIAQLMSLIINTFYSNK
Sbjct: 692 MPEETAQ----MEETEVETFAFQAEIAQLMSLIINTFYSNK 582
>11278
          Length = 988

 Score =  221 bits (563), Expect = 7e-58,   Method: Compositional matrix adjust.
 Identities = 114/214 (53%), Positives = 149/214 (69%), Gaps = 4/214 (1%)
 Frame = +1

Query: 15  EEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGK 74
           E+ E FAFQAE+ ++M LIIN+ Y NKEIFLRELISN+SDALDKIR+ SLT+   L +  
Sbjct: 250 EKSEKFAFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRFMSLTNKDVLHATD 429

Query: 75  ELHINLIPSKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADI---SMI 131
           EL I +    ++  L + DTGIGMT  DL+ NLGTIAKSGT  F+  +   +      +I
Sbjct: 430 ELSIKIKADTENHVLHVTDTGIGMTYNDLVKNLGTIAKSGTSDFLAKMGEASPTELNDLI 609

Query: 132 GQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDT-GEPMGRGTKVILHL 190
           GQFGVGFYS++LVA++V V +KHNDDEQY WES A  SF+V  D  G  +GRGT + LHL
Sbjct: 610 GQFGVGFYSSFLVADRVVVTSKHNDDEQYVWESDA-ESFSVAKDPRGNTLGRGTTISLHL 786

Query: 191 KEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEK 224
           KE+  ++LE   +  +VKK+SQFI + I ++  K
Sbjct: 787 KEEAHDFLEAGTLTSLVKKYSQFINFNIYMWSSK 888
>27487
          Length = 377

 Score =  154 bits (388), Expect = 2e-37,   Method: Compositional matrix adjust.
 Identities = 78/124 (62%), Positives = 106/124 (85%)
 Frame = -3

Query: 404 LQQSKILKVIRKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSEL 463
           LQQ+KILKVI+KN+VKKCLE+F E+AE+ ++YKKFYEQFSKN+KLGIHED+ NR KL +L
Sbjct: 372 LQQNKILKVIKKNIVKKCLEMFAEIAENNDDYKKFYEQFSKNLKLGIHEDTTNRTKLVDL 193

Query: 464 LRYYTSASGDEMVSLKDYCTRMKENQKHIYFITGETKDQVANSAFVERLRKHGLEVIYMI 523
           +R++TS SG++ +SLK+Y  RMKE QK I++ITGE++  V  S F+E+LRK G EV+Y++
Sbjct: 192 MRFHTSKSGEDQISLKEYIARMKEGQKDIFYITGESRAAVQASPFIEQLRKKGYEVLYLV 13

Query: 524 EPID 527
           +PID
Sbjct: 12  DPID 1
>25874
          Length = 476

 Score = 81.3 bits (199), Expect = 1e-15,   Method: Composition-based stats.
 Identities = 39/91 (42%), Positives = 57/91 (62%)
 Frame = +1

Query: 130 MIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILH 189
           +IGQFGVGFYS ++V ++V V TK +     A + S+ GS        E + RGTK+++H
Sbjct: 1   LIGQFGVGFYSTFMVGDRVDVFTKSHQPGSPALKWSSDGSGAYEVSEAEGVQRGTKIVVH 180

Query: 190 LKEDQTEYLEERRIKEIVKKHSQFIGYPITL 220
           LK D  ++ +E  I  +VKK+S F+G PI L
Sbjct: 181 LKGDSYDFAKEEIITGVVKKYSNFVGVPIYL 273
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6755152|ref|NP_035286.1| prolyl endopeptidase [Mus
musculus]
         (710 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

05811                                                                 687   0.0  
02177                                                                  31   2.0  
09774                                                                  30   2.3  
02203                                                                  30   3.5  
28249                                                                  28   8.6  
>05811
          Length = 2853

 Score =  687 bits (1772), Expect(2) = 0.0,   Method: Compositional matrix adjust.
 Identities = 319/544 (58%), Positives = 410/544 (75%), Gaps = 1/544 (0%)
 Frame = -2

Query: 1    MLSFQYPDVYRDETSVQEYHGHKICDPYSWLEDPDSEQTKAFVEAQNKITVPFLEQCPIR 60
            M  F YPD  RD++   ++ G K+ DPY WLEDPDSE+TKAFV+AQN ++ P+++ CP+ 
Sbjct: 2696 MYKFNYPDARRDDSVEDDFFGKKVSDPYRWLEDPDSEETKAFVDAQNDVSKPYIKTCPLA 2517

Query: 61   GLYKERMTELYDYPKYSCHFKKGKRYFYFYNTGLQNQRVLYVQDSLEGEARVFLDPNTLS 120
                +++T+ +DYPKY C  ++G +Y+YF+NTGLQNQ VLYVQDS++ EA V+ DPN LS
Sbjct: 2516 EKISDKITQRWDYPKYGCPRRRGDKYYYFHNTGLQNQSVLYVQDSVDSEATVYFDPNKLS 2337

Query: 121  DDGTVALRGYAFSEDGEYFAYGLSASGSDWVTIKFMKVDGAKELPDVLERVKFTCMAWTH 180
              GTVALR + FS+DG  +AY LS SGSDWVT+KF +    ++LPD L+ VKFT MAWT 
Sbjct: 2336 SKGTVALRSHWFSDDGSMWAYTLSESGSDWVTMKFKRAPSGEDLPDTLKYVKFTSMAWTQ 2157

Query: 181  DGKGMFYNSYPQQDGKSDGTETSTNLHQKLCYHVLGTDQSEDILCAEFPDEPKWMGGAEL 240
            D KG+FYN YP+ +GKSDGTET+++LH KL YH LGT+QSEDIL  E P+ P+WM GAE+
Sbjct: 2156 DVKGIFYNRYPESEGKSDGTETTSSLHHKLYYHRLGTEQSEDILVGEMPEFPRWMIGAEI 1977

Query: 241  SDDGRYVLLSIWEGCDPVNRLWYCDLQQEPNGITGILKWVKLIDNFEGEYDYVTNEGTVF 300
            SD GRY+LL+  EGCD VNRL+Y DL    +GITG L +VK++DNF+ EY+Y+TN GTVF
Sbjct: 1976 SDCGRYLLLTPREGCDHVNRLFYVDLNTLTDGITGKLPYVKIVDNFDAEYEYITNVGTVF 1797

Query: 301  TFKTNRNSPNYRLINIDFTDPDESKWKVLVPEHEKD-VLEWVACVRSNFLVLCYLHDVKN 359
            TFKTN+++P Y+L+NID + P+   W  LV E E   VLEW ACV    LV+CYL DVK+
Sbjct: 1796 TFKTNKDAPRYKLVNIDLSKPEPENWVTLVEEDEGGAVLEWTACVNQRQLVMCYLKDVKS 1617

Query: 360  ILQLHDLTTGALLKTFPLDVGSVVGYSGRKKDSEIFYQFTSFLSPGVIYHCDLTKEELEP 419
             L L+DL TGA     PL VGS+  YSGR KD+E+FY+FTSFL+PG I+  DLTK   EP
Sbjct: 1616 ELYLYDLETGASQYQVPLGVGSITAYSGRYKDTEMFYKFTSFLTPGEIFRLDLTKAPYEP 1437

Query: 420  MVFREVTVKGIDAADYQTIQIFYPSKDGTKIPMFIVHKKGIKLDGSHPAFLYGYGGFNIS 479
             +FR + V G +A  ++ +Q F+PSKDGTKIPMF++HK+G++L G HP  LYGYGGF+IS
Sbjct: 1436 KLFRSIAVPGFNADKFEVVQKFFPSKDGTKIPMFLIHKQGLELTGDHPVVLYGYGGFSIS 1257

Query: 480  ITPNYSVSRLIFVRHMGGVLAVANIRGGGEYGETWHKGGILANKQNCFDDFQCAAEYLIK 539
            ITP++S  R +FV+H+GG+ AVANIRGG EYGE WHK G L NKQNCFDDFQ AA++LI 
Sbjct: 1256 ITPDFSPHRTVFVQHLGGIYAVANIRGGNEYGEKWHKAGSLGNKQNCFDDFQAAAQFLID 1077

Query: 540  EGYT 543
              YT
Sbjct: 1076 NKYT 1065

 Score =  230 bits (587), Expect(2) = 0.0,   Method: Compositional matrix adjust.
 Identities = 105/164 (64%), Positives = 131/164 (79%)
 Frame = -3

Query: 545  PKRLTINGGSNGGLLVAACANQRPDLFGCVIAQVGVMDMLKFHKFTIGHAWTTDYGCSDT 604
            P+R+ INGGSNGGLLV A  NQRPDLF   IAQVGV+DML+FHKFTIGHAW +D+GC+D 
Sbjct: 1060 PERIAINGGSNGGLLVGASLNQRPDLFAAGIAQVGVLDMLRFHKFTIGHAWISDFGCADK 881

Query: 605  KQHFEWLLKYSPLHNVKLPEADDIQYPSMLLLTADHDDRVVPLHSLKFIATLQYIVGRSR 664
            +  F WL+KYSPLH +   +    QYP++LLLT DHDDRVVPLHSLKFIA LQ+ +GR  
Sbjct: 880  EDEFGWLIKYSPLHAIP-SDPKGGQYPAVLLLTGDHDDRVVPLHSLKFIAQLQHXLGRRD 704

Query: 665  KQSNPLLIHVDTKAGHGAGKPTAKVIEEVSDMFAFIARCLNIEW 708
             Q+NPLLI VDT +GHGAGKPT+K IEEV+++++F+   L ++W
Sbjct: 703  NQTNPLLIRVDTDSGHGAGKPTSKYIEEVTEIYSFLCLTLGLQW 572
>02177
          Length = 1030

 Score = 30.8 bits (68), Expect = 2.0,   Method: Compositional matrix adjust.
 Identities = 17/43 (39%), Positives = 21/43 (48%)
 Frame = -2

Query: 280 VKLIDNFEGEYDYVTNEGTVFTFKTNRNSPNYRLINIDFTDPD 322
           VK     EG  DY   +   F  K   N+P YRLI + FT+ D
Sbjct: 903 VKFRRRREGRTDYFARKRLTFQDKNKYNTPKYRLI-VRFTNKD 778
>09774
          Length = 1829

 Score = 30.4 bits (67), Expect = 2.3,   Method: Compositional matrix adjust.
 Identities = 13/49 (26%), Positives = 23/49 (46%)
 Frame = -3

Query: 575 IAQVGVMDMLKFHKFTIGHAWTTDYGCSDTKQHFEWLLKYSPLHNVKLP 623
           +AQ G  +++ FH  ++ H       C D   H   L +  P H+++ P
Sbjct: 423 LAQCGGWELVSFHHLSVAHPG*CPTSCKDLCYHHHLLYQXRPPHHLERP 277
>02203
          Length = 1671

 Score = 30.0 bits (66), Expect = 3.5,   Method: Compositional matrix adjust.
 Identities = 13/49 (26%), Positives = 23/49 (46%)
 Frame = -3

Query: 575  IAQVGVMDMLKFHKFTIGHAWTTDYGCSDTKQHFEWLLKYSPLHNVKLP 623
            +AQ G  +++ FH  ++ H       C D   H   L +  P H+++ P
Sbjct: 1432 LAQCGGWELVSFHHLSVAHPG*CPTSCKDLCYHHHLLYQXRPPHHLERP 1286
>28249
          Length = 442

 Score = 28.5 bits (62), Expect = 8.6,   Method: Composition-based stats.
 Identities = 21/82 (25%), Positives = 38/82 (46%), Gaps = 10/82 (12%)
 Frame = -3

Query: 300 FTFKTNRNSPNYRLIN----IDFTDPDESKWKVLVPEHEKDVL------EWVACVRSNFL 349
           ++ KT    P YR +N    +++TDP     +      +K +L       W  C   +  
Sbjct: 437 YSLKTVNLQPRYRTLNEGIRLNYTDPSACAAR*CATLVKKKIL*PLQYQVWPICAPRS-- 264

Query: 350 VLCYLHDVKNILQLHDLTTGAL 371
           V+C + D+K+   L+ LT G++
Sbjct: 263 VVCIIKDIKSRALLYFLTNGSV 198
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6755901|ref|NP_035783.1| tubulin, alpha 1 [Mus
musculus]
         (451 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

00276                                                                 686   0.0  
12457                                                                 460   e-134
06360                                                                 341   4e-94
03702                                                                 282   2e-76
17215                                                                 244   6e-65
16482                                                                 214   5e-56
13181                                                                 184   6e-47
04882                                                                 172   2e-43
05902                                                                 137   8e-33
25015                                                                 115   4e-26
39157                                                                  96   3e-20
28905                                                                  91   1e-18
31457                                                                  87   2e-17
26304                                                                  29   4.7  
>00276
          Length = 1330

 Score =  686 bits (1769), Expect = 0.0,   Method: Compositional matrix adjust.
 Identities = 328/353 (92%), Positives = 335/353 (94%)
 Frame = -3

Query: 80   TGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFH 139
            TGTYRQL  PEQL+TGKEDAANNYARGHYTIGKE++DLVLDRIRKLADQCTGLQGFL+FH
Sbjct: 1328 TGTYRQL-SPEQLVTGKEDAANNYARGHYTIGKELVDLVLDRIRKLADQCTGLQGFLIFH 1152

Query: 140  XXXXXXXXXXXXLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSD 199
                        L MERLSVDYGKKSKLEF IYPAPQVSTAVVEPYNSILTTHTTLEHSD
Sbjct: 1151 SFGGGTGSGFTSLXMERLSVDYGKKSKLEFXIYPAPQVSTAVVEPYNSILTTHTTLEHSD 972

Query: 200  CAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNL 259
            CAFMVDNEAIYDICRRNLDIERPTYTNLNRLI QIVSSITASLRFDGALNVDLTEFQTNL
Sbjct: 971  CAFMVDNEAIYDICRRNLDIERPTYTNLNRLIXQIVSSITASLRFDGALNVDLTEFQTNL 792

Query: 260  VPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLY 319
            VPYPRIHFPLATYAPVISAEKAYHEQL VAEITNACFEPANQ+VKCDPRHGKYMACC+LY
Sbjct: 791  VPYPRIHFPLATYAPVISAEKAYHEQLXVAEITNACFEPANQLVKCDPRHGKYMACCMLY 612

Query: 320  RGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLS 379
            RGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLS
Sbjct: 611  RGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLS 432

Query: 380  NTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDY 432
            NTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEARED+AALEKDY
Sbjct: 431  NTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDY 273
>12457
          Length = 781

 Score =  460 bits (1183), Expect(2) = e-134,   Method: Compositional matrix adjust.
 Identities = 220/239 (92%), Positives = 226/239 (94%)
 Frame = -1

Query: 67  FVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLA 126
            VDLEPTV+DEVRTGTYRQLFHPEQL+TGKEDAANNYARGHYTIGKEI+DLVLDRIRKLA
Sbjct: 718 LVDLEPTVVDEVRTGTYRQLFHPEQLVTGKEDAANNYARGHYTIGKEIVDLVLDRIRKLA 539

Query: 127 DQCTGLQGFLVFHXXXXXXXXXXXXLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYN 186
           DQCTGLQGFL+FH            LLMERLSVDYGKKSKLEF+IYPAPQVSTAVVEPYN
Sbjct: 538 DQCTGLQGFLIFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFAIYPAPQVSTAVVEPYN 359

Query: 187 SILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLRFDG 246
           SILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLRFDG
Sbjct: 358 SILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLRFDG 179

Query: 247 ALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKC 305
           ALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQL+VAEITNACFEPANQMVKC
Sbjct: 178 ALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLTVAEITNACFEPANQMVKC 2

 Score = 38.1 bits (87), Expect(2) = e-134,   Method: Compositional matrix adjust.
 Identities = 20/28 (71%), Positives = 20/28 (71%)
 Frame = -2

Query: 45  GDDSFNTFFSETGAGKHVPRAVFVDLEP 72
           GDDSF T  SETGAGKHVPRAV     P
Sbjct: 780 GDDSF-TPLSETGAGKHVPRAVSSXXSP 700
>06360
          Length = 1896

 Score =  341 bits (874), Expect = 4e-94,   Method: Compositional matrix adjust.
 Identities = 159/178 (89%), Positives = 166/178 (93%)
 Frame = -1

Query: 1    MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGK 60
            MRECIS+HVGQAGVQ+GNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGK
Sbjct: 1710 MRECISVHVGQAGVQMGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGK 1531

Query: 61   HVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLD 120
            HVPRAVFVDLEPTV+DEVRTGTYRQLFHPEQL+TGKEDAANNYARGHYTIGKEI+DLVLD
Sbjct: 1530 HVPRAVFVDLEPTVVDEVRTGTYRQLFHPEQLVTGKEDAANNYARGHYTIGKEIVDLVLD 1351

Query: 121  RIRKLADQCTGLQGFLVFHXXXXXXXXXXXXLLMERLSVDYGKKSKLEFSIYPAPQVS 178
            RIRKLADQCTGLQGFL+FH            LLMERLSVDYGKKSKLEF+IYPAPQVS
Sbjct: 1350 RIRKLADQCTGLQGFLIFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFAIYPAPQVS 1177
>03702
          Length = 1932

 Score =  282 bits (721), Expect = 2e-76,   Method: Compositional matrix adjust.
 Identities = 138/153 (90%), Positives = 142/153 (92%)
 Frame = +1

Query: 155  ERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICR 214
            ERLSVDYGKKSKLEF+IYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICR
Sbjct: 1459 ERLSVDYGKKSKLEFAIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICR 1638

Query: 215  RNLDIERPTYTNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAP 274
            RNLDIERP YTNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNLVP P    P     P
Sbjct: 1639 RNLDIERPXYTNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNLVPTPH-PLPPGHLCP 1815

Query: 275  VISAEKAYHEQLSVAEITNACFEPANQMVKCDP 307
            VISAEKAYHEQL+VAE+TNACFEPANQ+VKCDP
Sbjct: 1816 VISAEKAYHEQLTVAEVTNACFEPANQLVKCDP 1914
>17215
          Length = 632

 Score =  244 bits (622), Expect = 6e-65,   Method: Compositional matrix adjust.
 Identities = 114/116 (98%), Positives = 116/116 (100%)
 Frame = +3

Query: 317 LLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVC 376
           +LYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVC
Sbjct: 3   MLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVC 182

Query: 377 MLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDY 432
           MLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEARED+AALEKDY
Sbjct: 183 MLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDY 350
>16482
          Length = 837

 Score =  214 bits (545), Expect = 5e-56,   Method: Compositional matrix adjust.
 Identities = 105/248 (42%), Positives = 149/248 (60%)
 Frame = +1

Query: 1   MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGK 60
           MRE + +  GQ G QIG   WE+   EHGI P G    D  +    +  N +++E   GK
Sbjct: 100 MREIVHMQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQL--ERINVYYNEATGGK 273

Query: 61  HVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLD 120
           +VPRAV VDLEP  +D VR+G + Q+F P+  + G+  A NN+A+GHYT G E++D VLD
Sbjct: 274 YVPRAVLVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLD 453

Query: 121 RIRKLADQCTGLQGFLVFHXXXXXXXXXXXXLLMERLSVDYGKKSKLEFSIYPAPQVSTA 180
            +RK A+ C  LQGF + H            LL+ ++  +Y  +    FS+ P+P+VS  
Sbjct: 454 VVRKEAESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVVPSPKVSDT 633

Query: 181 VVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITA 240
           VVEPYN+ L+ H  +E++D  + +DNEA+YDIC R L +  PTY +LN L+   +S +T 
Sbjct: 634 VVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTT 813

Query: 241 SLRFDGAL 248
            LRF G L
Sbjct: 814 CLRFPGQL 837
>13181
          Length = 1092

 Score =  184 bits (467), Expect = 6e-47,   Method: Compositional matrix adjust.
 Identities = 83/223 (37%), Positives = 128/223 (57%)
 Frame = -3

Query: 210  YDICRRNLDIERPTYTNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPL 269
            YDIC R L +  PTY +LN L+   +S +T  LRF G LN DL +   N+VP+PR+HF +
Sbjct: 1090 YDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFM 911

Query: 270  ATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVN 329
              +AP+ S     +  L+V E+T   F+  N M  CDPRHG+Y+    ++RG +  K+V+
Sbjct: 910  PGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAMFRGRMSMKEVD 731

Query: 330  AAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWA 389
              +  ++ K +  FV+W P   K  +   PP          ++ +   + N+TAI E + 
Sbjct: 730  EQMLNVQNKNSSYFVEWIPNNVKTAVCDIPP--------RGLKMSATFVGNSTAIQELFK 575

Query: 390  RLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDY 432
            R+  +F  M+ ++AF+HWY GEGM+E EF+EA  +M  L  +Y
Sbjct: 574  RISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEY 446
>04882
          Length = 1136

 Score =  172 bits (437), Expect = 2e-43,   Method: Compositional matrix adjust.
 Identities = 77/214 (35%), Positives = 122/214 (57%)
 Frame = +2

Query: 219 IERPTYTNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISA 278
           +  PTY +LN L+   +S +T  LRF G LN DL +   N+VP+PR+HF +  +AP+ S 
Sbjct: 314 VHTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSR 493

Query: 279 EKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTK 338
               +  L+V E+T   F+  N M  CDPRHG+Y+    ++RG +  K+V+  +  ++ K
Sbjct: 494 GSQQYRALTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNK 673

Query: 339 RTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLM 398
            +  FV+W P   K  +   PP          ++ +   + N+TAI E + R+  +F  M
Sbjct: 674 NSSYFVEWIPNNVKTAVCDIPPR--------GLKMSATFIGNSTAIQELFKRISEQFTAM 829

Query: 399 YAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDY 432
           + ++AF+HWY GEGM+E EF+EA  +M  L  +Y
Sbjct: 830 FRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEY 931
>05902
          Length = 1127

 Score =  137 bits (345), Expect = 8e-33,   Method: Compositional matrix adjust.
 Identities = 81/289 (28%), Positives = 158/289 (54%), Gaps = 9/289 (3%)
 Frame = +2

Query: 153 LMERLSVDYGKKSKLEFSIYP-APQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYD 211
           L+E+L+  + KK    +S++P   ++S  VV+PYNS+LT     +++DC  ++DN A+  
Sbjct: 65  LLEKLNDRFPKKLIQTYSVFPNVDEISDVVVQPYNSLLTLKRLTQNADCVVVLDNTALNR 244

Query: 212 ICRRNLDIERPTYTNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLAT 271
           I    L I+ PT+  +N+L+  ++S+ T +LR+ G +N DL     +L+P PR+HF +  
Sbjct: 245 IAADRLHIDTPTFAQVNQLVSTVMSTSTTTLRYPGYMNNDLIGLIASLIPTPRLHFLMTG 424

Query: 272 YAPVIS-AEKAYHEQLSVAEITNACFEPANQMVKCDPRHGK----YMACCLLYRGDVVPK 326
           Y P+ + ++ A   + +V ++     +P N MV   P H +    Y++   + +G+V P 
Sbjct: 425 YTPLTTDSQVANVRKTTVLDVMRRLLQPKNMMVST-PVHRQANHCYISILNIIQGEVDPT 601

Query: 327 DVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAE 386
            V+ ++  I+ ++  QF+ W P   +V ++ + P V     ++ +     ML+N T+I+ 
Sbjct: 602 QVHKSLQRIRERKLAQFIPWGPASIQVALSRKSPYVQTAHRVSGL-----MLANHTSISH 766

Query: 387 AWARLDHKFDLMYAKRAFVHWYVGEGMEE---GEFSEAREDMAALEKDY 432
            + R+  ++D +  + AF+  +  E + +    EF  +RE +  L  +Y
Sbjct: 767 LFERILRQYDKLRKREAFMDQFKKEAIFKDNLDEFDNSREALQLLVDEY 913
>25015
          Length = 458

 Score =  115 bits (287), Expect = 4e-26,   Method: Compositional matrix adjust.
 Identities = 54/119 (45%), Positives = 75/119 (63%)
 Frame = -3

Query: 21  WELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRT 80
           WE+   EHGI P G    D  +    +  N +++E   GK+VPRAV VDLEP  +D VR+
Sbjct: 360 WEVISDEHGIDPTGTYHGDSDLQ--LERINVYYNEATGGKYVPRAVLVDLEPGTMDSVRS 187

Query: 81  GTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFH 139
           G + Q+F P+  + G+  A NN+A+GHYT G E++D VLD +RK A+ C  LQGF + H
Sbjct: 186 GPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEAESCDCLQGFQLTH 10
>39157
          Length = 488

 Score = 95.9 bits (237), Expect = 3e-20,   Method: Compositional matrix adjust.
 Identities = 51/127 (40%), Positives = 73/127 (57%), Gaps = 3/127 (2%)
 Frame = -1

Query: 1   MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGK 60
           MRE + +  GQ G QIG   WE+   EHGI P G    D  +    +  N +++E   GK
Sbjct: 443 MREIVHLQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQ--LERINVYYNEATGGK 270

Query: 61  HVPRAVFVDLEPTVIDEVRTGT--YRQLFHPEQLITGKEDAANNYARGHYTI-GKEIIDL 117
           +VPRAV VDLEP  +D VR+G+    ++F P+  + G+  A NN+ +   T  G E++D 
Sbjct: 269 YVPRAVLVDLEPGTMDSVRSGSPFGPKIFRPDNFVFGQSGAGNNWGQKDTTQRGAELVDS 90

Query: 118 VLDRIRK 124
           VLD +RK
Sbjct: 89  VLDVVRK 69
>28905
          Length = 425

 Score = 90.5 bits (223), Expect = 1e-18,   Method: Composition-based stats.
 Identities = 36/103 (34%), Positives = 59/103 (57%)
 Frame = -1

Query: 258 NLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCL 317
           N+VP+PR+HF +  +AP+ S     +  L+V E+T   F+  N M  CDPRHG+Y+    
Sbjct: 380 NMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAA 201

Query: 318 LYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPP 360
           ++RG +  K+V+  +  ++ K +  FV+W P   K  +   PP
Sbjct: 200 MFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPP 72
>31457
          Length = 1530

 Score = 86.7 bits (213), Expect = 2e-17,   Method: Compositional matrix adjust.
 Identities = 39/122 (31%), Positives = 67/122 (54%)
 Frame = +3

Query: 311 KYMACCLLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAK 370
           KY+    ++RG +  K+V+  +  ++ K +  FV+W P   K  +   PP          
Sbjct: 234 KYLTVAAMFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPR--------G 389

Query: 371 VQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEK 430
           ++ +   + N+TAI E + R+  +F  M+ ++AF+HWY GEGM+E EF+EA  +M  L  
Sbjct: 390 LKMSSTFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS 569

Query: 431 DY 432
           +Y
Sbjct: 570 EY 575
>26304
          Length = 1290

 Score = 28.9 bits (63), Expect = 4.7,   Method: Compositional matrix adjust.
 Identities = 13/27 (48%), Positives = 18/27 (66%)
 Frame = -2

Query: 106  GHYTIGKEIIDLVLDRIRKLADQCTGL 132
            G  T+GK I DL L++IR ++ QC  L
Sbjct: 1103 GGSTLGKFIFDLQLNQIRNISLQCESL 1023
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6806903|ref|NP_033852.1| ATPase, Ca++ transporting,
slow twitch 2 isoform b [Mus musculus]
         (998 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

06342                                                                1113   0.0  
00499                                                                 263   2e-70
36566                                                                 143   3e-34
12151                                                                  84   1e-23
14773                                                                  87   4e-17
28890                                                                  85   2e-16
29829                                                                  80   5e-15
08160                                                                  78   2e-14
04985                                                                  68   2e-11
13525                                                                  49   7e-06
14321                                                                  49   1e-05
33697                                                                  44   3e-04
07486                                                                  35   0.17 
11991                                                                  31   3.0  
31731                                                                  30   4.2  
>06342
          Length = 2428

 Score = 1113 bits (2878), Expect = 0.0,   Method: Compositional matrix adjust.
 Identities = 537/738 (72%), Positives = 622/738 (84%), Gaps = 1/738 (0%)
 Frame = +2

Query: 145 IVPGDIVEIAVGDKVPADIRLTSIKSTTLRVDQSILTGESVSVIKHTDPVPDPRAVNQDK 204
           +VPGDIVE++VGDKVPADIR+  I STTLR+DQ+ILTGESVSV+KHTDP+PDPRAVNQDK
Sbjct: 5   LVPGDIVEVSVGDKVPADIRILKIHSTTLRIDQAILTGESVSVMKHTDPIPDPRAVNQDK 184

Query: 205 KNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMVATEQERTPLQQKLDEFGEQLSKVI 264
           KN+LFSGTN+AAGK  G+V+ TG+ TEIGKIR+EM+ TEQE+TPLQQKLDEF  QLSKVI
Sbjct: 185 KNLLFSGTNVAAGKCKGLVIGTGLTTEIGKIRNEMMDTEQEKTPLQQKLDEFSNQLSKVI 364

Query: 265 SLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAVALAVAAIPEGLPAVITTCLALGTR 324
           ++ICIAVW INIGHFNDP HGGSWI+GAIYYFKIAVALAVAAIPEGLPAVITTCLALGTR
Sbjct: 365 TIICIAVWAINIGHFNDPAHGGSWIKGAIYYFKIAVALAVAAIPEGLPAVITTCLALGTR 544

Query: 325 RMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCRMFILDKVEGDTCSLNEFSI 384
           RMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVC++FI  +++ +     +F +
Sbjct: 545 RMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCKLFIFSQIDTNQIKTTQFEV 724

Query: 385 TGSTYAPIGEVQKDDKPVKCHQYDGLVELATICALCNDSALDYNEAKGVYEKVGEATETA 444
           TGSTYAP GE+ ++ K VK   Y GL EL TIC +CNDS++DYNEAK  YEKVGEATETA
Sbjct: 725 TGSTYAPDGELYQNGKKVKASDYPGLEELCTICGMCNDSSVDYNEAKTQYEKVGEATETA 904

Query: 445 LTCLVEKMNVFDTELKGLSKIERANACNSVIKQLMKKEFTLEFSRDRKSMSVYCTPNKPS 504
           LT L EK+N ++T+   L+K E    CN VI+ + +KEFTLEFSRDRKSMSV+C PNKP+
Sbjct: 905 LTVLAEKLNFYNTDKSSLNKREMGTVCNHVIQDMWRKEFTLEFSRDRKSMSVFCVPNKPT 1084

Query: 505 RT-SMSKMFVKGAPEGVIDRCTHIRVGSTKVPMTPGVKQKIMSVIREWGSGSDTLRCLAL 563
           R    ++MF KGAPEG++DRCTH+R+G+ KVPM+P +K +IM + + +G+G DTLRCLAL
Sbjct: 1085RVPGGARMFAKGAPEGLLDRCTHVRIGNNKVPMSPAIKNEIMKLTKIYGTGRDTLRCLAL 1264

Query: 564 ATHDNPLKREEMHLEDSANFIKYETNLTFVGCVGMLDPPRIEVASSVKLCRQAGIRVIMI 623
           AT DNP +RE+M LEDS  FI+YETN+TFVG VGMLDPPR EV +S+K CR AGIRVI+I
Sbjct: 1265ATIDNPPRREDMDLEDSRKFIEYETNMTFVGVVGMLDPPREEVMASIKNCRAAGIRVIVI 1444

Query: 624 TGDNKGTAVAICRRIGIFGQDEDVTSKAFTGREFDELSPSAQRDACLNARCFARVEPSHK 683
           TGDNK TA AICRRIG+F + E+    A+TGREFDEL P  QR A + AR FARVEP+HK
Sbjct: 1445TGDNKATAEAICRRIGVFSESENTEGLAYTGREFDELPPEDQRAAVMRARLFARVEPAHK 1624

Query: 684 SKIVEFLQSFDEITAMTGDGVNDAPALKKSEIGIAMGSGTAVAKTASEMVLADDNFSTIV 743
           SKIVE+LQ+  EI+AMTGDGVNDAPALKK+EIGIAMGSGTAVAK+ASEMVLADDNFSTIV
Sbjct: 1625SKIVEYLQAEGEISAMTGDGVNDAPALKKAEIGIAMGSGTAVAKSASEMVLADDNFSTIV 1804

Query: 744 AAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAALGFPEALIPVQLLWVNLVTDGLPA 803
           AAVEEGRAIYNNMKQFIRYLISSN+GEVVCIFLTAALG PEALIPVQLLWVNLVTDG PA
Sbjct: 1805AAVEEGRAIYNNMKQFIRYLISSNIGEVVCIFLTAALGIPEALIPVQLLWVNLVTDGFPA 1984

Query: 804 TALGFNPPDLDIMNKPPRNPKEPLISGWLFFRYLAIGCYVXXXXXXXXXXXXXXXXXXPR 863
           TALGFNPPDLDIM KPPRNP+E LI+GWLFFRY+AIG YV                  PR
Sbjct: 1985TALGFNPPDLDIMQKPPRNPREGLITGWLFFRYMAIGIYVGCATVGAAAWWFMLYDKGPR 2164

Query: 864 VSFYQLSHFLQCKEDNPD 881
           +++YQL+H +QC  +  D
Sbjct: 2165LNYYQLTHHMQCPAEPQD 2218

 Score =  118 bits (295), Expect = 1e-26,   Method: Compositional matrix adjust.
 Identities = 56/69 (81%), Positives = 60/69 (86%)
 Frame = +3

Query: 882  FDGVDCAIFESPYPMTMALSVLVTIEMCNALNSLSENQSLLRMPPWENIWLVGSICLSMS 941
            F GVDC IF +P PMTMALSVLVTIEM NALNSLSENQSL  MPPW N WLVG+ICLSM+
Sbjct: 2220 FKGVDCNIFSAPEPMTMALSVLVTIEMLNALNSLSENQSLTVMPPWINKWLVGAICLSMA 2399

Query: 942  LHFLILYVE 950
            LHFLILYV+
Sbjct: 2400 LHFLILYVD 2426
>00499
          Length = 4026

 Score =  263 bits (673), Expect = 2e-70,   Method: Compositional matrix adjust.
 Identities = 194/559 (34%), Positives = 296/559 (52%), Gaps = 39/559 (6%)
 Frame = +2

Query: 310 GLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCRMFIL 369
           GL A +T CL L  +RMA+KN +V++L +VETLG TS ICSDKTGTLT N+M+V  M+  
Sbjct: 2   GLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFD 181

Query: 370 DK-VEGDTCSLNEFSITGSTYAPIGEVQKDDKPVKCHQYDGLVELATICALCNDSALDYN 428
            + VE DT S ++ + T S   P                   + L+ +  LCN +     
Sbjct: 182 GRIVEADT-SDDQSNATYSRSDPT-----------------WMALSRVAMLCNRA----- 292

Query: 429 EAKGVYEKV--------GEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIKQLMK 480
           E KG  + V        G+A+E+AL   VE        +  +++  R N      +++++
Sbjct: 293 EFKGNQDNVPILKRECNGDASESALLKCVE------LSIGHVTEYRRRN------EKIVE 436

Query: 481 KEFTLEFSRDRKSMSVYCT--PNKPSRTSMSKMFVKGAPEGVIDRCTHIRVGSTKVPMTP 538
             F    S ++  +S++ T  P+ P       + +KGAPE ++DRC+ I +   + P+  
Sbjct: 437 IPFN---SSNKYQVSIHETEDPDDPRYL----LVMKGAPERIMDRCSTILLNGKEQPLDD 595

Query: 539 GVKQKIMSVIREWGSGSDTLRCLALATHDNPLKREEMHLE---DSANFIKYETNLTFVGC 595
             ++   +   E G   +  R L    +  P+ +     E   +  NF    T L FVG 
Sbjct: 596 NFREAFNAAYLELGGLGE--RVLGFCDYFLPVDQFPPGYEFDPEGPNFPI--TGLRFVGL 763

Query: 596 VGMLDPPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQD----EDVTSK- 650
           + M+DPPR  V  +V  CR AGI+VIM+TGD+  TA AI R +GI  +     ED+ S+ 
Sbjct: 764 MAMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIARGVGIISEGSKTVEDIASER 943

Query: 651 ---------------AFTGREFDELSPSAQRDACLNARC---FARVEPSHKSKIVEFLQS 692
                             G +  +++P AQ D  L       FAR  P  K  IVE  Q 
Sbjct: 944 GIPVEEVDPREAKAAVIHGGDLRDMTP-AQIDEILRNHSEIVFARTSPQQKLIIVEGCQR 1120

Query: 693 FDEITAMTGDGVNDAPALKKSEIGIAMG-SGTAVAKTASEMVLADDNFSTIVAAVEEGRA 751
             +I A+TGDGVND+PALKK++IG+AMG +G+ V+K A++M+L DDNF++IV  VEEGR 
Sbjct: 1121QGQIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILLDDNFASIVTGVEEGRL 1300

Query: 752 IYNNMKQFIRYLISSNVGEVVCIFLTAALGFPEALIPVQLLWVNLVTDGLPATALGFNPP 811
           I++N+K+ I Y ++SN+ E+    L      P  L  + +L ++L TD +PA +L +   
Sbjct: 1301IFDNLKKSIAYTLTSNIPEISPFLLFILADIPLPLGTITILCIDLGTDMVPAISLAYEKA 1480

Query: 812 DLDIMNKPPRNP-KEPLIS 829
           + DIM + PR+P K+ L++
Sbjct: 1481ENDIMKRQPRDPVKDKLVN 1537
>36566
          Length = 589

 Score =  143 bits (361), Expect = 3e-34,   Method: Composition-based stats.
 Identities = 69/160 (43%), Positives = 107/160 (66%), Gaps = 1/160 (0%)
 Frame = +3

Query: 680 PSHKSKIVEFLQSFDEITAMTGDGVNDAPALKKSEIGIAMG-SGTAVAKTASEMVLADDN 738
           P   S+    LQ    +  MTGDGVNDA ALK +EIGI+MG SGT V+K AS+M+L DD+
Sbjct: 78  PGTSSRSSRRLQQNGLVVGMTGDGVNDAVALKSAEIGISMGVSGTDVSKEASDMILVDDD 257

Query: 739 FSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAALGFPEALIPVQLLWVNLVT 798
           F+TI+ A+EEG+ I+ N++ F+R+ +S+++  +  I ++  L  P  L  +Q+LW+N++ 
Sbjct: 258 FTTILNAIEEGKGIFYNIRNFVRFQLSTSIAALSLIAVSTLLRLPNPLNAMQILWINIIM 437

Query: 799 DGLPATALGFNPPDLDIMNKPPRNPKEPLISGWLFFRYLA 838
           DG PA +LG  P D D++ +PPR+  +P+I+  L    L+
Sbjct: 438 DGPPAQSLGVEPVDHDVIKQPPRHVGDPIITRRLIINVLS 557
>12151
          Length = 880

 Score = 83.6 bits (205), Expect(2) = 1e-23,   Method: Compositional matrix adjust.
 Identities = 50/133 (37%), Positives = 81/133 (60%), Gaps = 1/133 (0%)
 Frame = +3

Query: 711 KKSEIGIAMG-SGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVG 769
           +K+++G AMG SGT VAK AS+++L DDNF++IV AV  GR +Y+++ +F+++ ++ NV 
Sbjct: 288 QKADVGFAMGISGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSIAKFLQFQLTVNVV 467

Query: 770 EVVCIFLTAALGFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPLIS 829
            V   F+ A       L  +Q+LWVNL+ D L + AL    P  +++ + P    +PLIS
Sbjct: 468 AVFVAFVGACSIGDSPLKAIQMLWVNLIMDTLASLALATELPSSELLKRRPYGRTKPLIS 647

Query: 830 GWLFFRYLAIGCY 842
             ++   L    Y
Sbjct: 648 KTMWKNILGHAFY 686

 Score = 45.8 bits (107), Expect(2) = 1e-23,   Method: Composition-based stats.
 Identities = 33/100 (33%), Positives = 47/100 (47%), Gaps = 13/100 (13%)
 Frame = +1

Query: 626 DNKGTAVAICRRIGIFGQDEDVTSKAFTGREFDELSPSAQRDACL--------NARCFAR 677
           DN  TA +I  + GI    +D       G+EF++L   A+ +           N R  AR
Sbjct: 1   DNVNTARSIASKCGIIQPGDD--GLVLEGKEFNQLIRDAEGEISQEKVDEVWPNLRVLAR 174

Query: 678 VEPSHKSKIVEFL-----QSFDEITAMTGDGVNDAPALKK 712
             P  K  +V+ +      +  E+ A+TGDG ND PALKK
Sbjct: 175 SSPQDKYILVKHIIDSKVSTSREVVAVTGDGTNDGPALKK 294
>14773
          Length = 794

 Score = 87.0 bits (214), Expect = 4e-17,   Method: Compositional matrix adjust.
 Identities = 41/105 (39%), Positives = 69/105 (65%)
 Frame = +2

Query: 725 VAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAALGFPE 784
           V+K A++M+L DDNF++IV  VEEGR I++N+K+ I Y ++SN+ E+    +    G P 
Sbjct: 8   VSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEISPFLVYILFGTPL 187

Query: 785 ALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPLIS 829
            L  + +L+++L TD +PA +L +   + DIM +PPR   + L++
Sbjct: 188 PLGVITILFIDLGTDMVPAISLAYEMAESDIMKRPPRTISDRLVN 322
>28890
          Length = 552

 Score = 84.7 bits (208), Expect = 2e-16,   Method: Compositional matrix adjust.
 Identities = 56/200 (28%), Positives = 100/200 (50%), Gaps = 7/200 (3%)
 Frame = -3

Query: 102 AIVGVWQERNAENAIEALKEYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAVGDKVPA 161
            +   +QE  +   +++ K   P+   V R D+K    +KA+++V GDIVE   GD+VPA
Sbjct: 544 GVFSYYQEAKSSKIMDSFKNLVPQFAVVVRGDQK--LSVKAEELVVGDIVECKFGDRVPA 371

Query: 162 DIRLTSIKSTTLRVDQSILTGES-----VSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAA 216
           D+R+  I +   +VD S LTGES      +   H +P+        + +N+ F  TN   
Sbjct: 370 DLRV--ISAHGFKVDNSSLTGESEPQSRSAEFTHENPL--------ETRNICFFSTNAVE 221

Query: 217 GKAMGVVVATGVNTEIGKIRDEMVATEQERTPLQQKLDEFGEQLSKVISLICIAVWIIN- 275
           G   G+V+ TG +T +G+I +     E   TP+ +++  F   ++ V   + ++ ++I  
Sbjct: 220 GTCRGIVIKTGDDTVMGRIANLASGLEVGDTPIAKEIAHFIHIITGVAVFLGVSFFVIAF 41

Query: 276 -IGHFNDPVHGGSWIRGAIY 294
            +G+F        W+   I+
Sbjct: 40  ILGYF--------WLDAVIF 5
>29829
          Length = 465

 Score = 79.7 bits (195), Expect = 5e-15,   Method: Compositional matrix adjust.
 Identities = 48/120 (40%), Positives = 75/120 (62%), Gaps = 1/120 (0%)
 Frame = -3

Query: 715 IGIAMG-SGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVC 773
           +G AMG SGT VAK AS+++L DDNF++IV AV  GR +Y+++ +F+++ ++ NV  V  
Sbjct: 460 LGFAMGISGTDVAKEASDIILTDDNFTSIVKAVXWGRNVYDSIAKFLQFQLTVNVVAVFV 281

Query: 774 IFLTAALGFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPLISGWLF 833
            F+ A       L  +Q+LWVNL+ D L + AL    P  +++ + P    +PLIS  +F
Sbjct: 280 AFVGACSIGDSPLEAIQMLWVNLIMDTLASLALATELPSNELLKRKPYGRTKPLISKTMF 101
>08160
          Length = 459

 Score = 78.2 bits (191), Expect = 2e-14,   Method: Compositional matrix adjust.
 Identities = 44/90 (48%), Positives = 58/90 (64%), Gaps = 4/90 (4%)
 Frame = +2

Query: 310 GLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCRMFIL 369
           GL A +T CL L  +RMA+KN +V++L +VETLG TS ICSDKTGTLT N+M+V  M+  
Sbjct: 2   GLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFD 181

Query: 370 DK-VEGDTC---SLNEFSITGSTYAPIGEV 395
            + VE DT    S   +S T  T+  +  V
Sbjct: 182 GRIVEADTSDDQSNATYSRTDVTWMALARV 271
>04985
          Length = 1671

 Score = 67.8 bits (164), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 52/175 (29%), Positives = 77/175 (44%), Gaps = 10/175 (5%)
 Frame = -1

Query: 656  EFDELSPSAQRDACLNARCFARVEPSHKSKIVEFLQSFDEITAMTGDGVNDAPALKKSEI 715
             F EL P      C     FAR+ P  K  ++E LQS+D I  M GDG ND  ALK +  
Sbjct: 1650 HFPELLP----KVCTQGTVFARMAPDQKCALIENLQSYDYIVGMCGDGANDCEALKAAHA 1483

Query: 716  GIAMGSGTAVAKTASEMVLADDNFSTIVAAVEEGRAI---------YNNMKQFIRYLISS 766
            GI++    A A  A+      +N   +V A+ EGRA          Y  +  FI+++   
Sbjct: 1482 GISLSE--AEASVAAPFTSRINNIECVVTAMREGRAALVTSFGCFKYMALYSFIQFI--- 1318

Query: 767  NVGEVVCIFLTAALGFPEALIPVQLLWVNLVTDGLPATALGFN-PPDLDIMNKPP 820
                 V I  T      +    ++ L+++L+     A  LG+    D  + +KPP
Sbjct: 1317 ----SVLILYTCQTNLSD----LEFLYIDLIITTTIAVLLGYTGAYDKLVRHKPP 1177
>13525
          Length = 645

 Score = 49.3 bits (116), Expect = 7e-06,   Method: Composition-based stats.
 Identities = 22/34 (64%), Positives = 28/34 (82%)
 Frame = +2

Query: 321 LGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTG 354
           L  +RMA+KN +V++L +VETLG TS ICSDKTG
Sbjct: 2   LTAKRMARKNCLVKNLEAVETLGSTSTICSDKTG 103
>14321
          Length = 568

 Score = 48.5 bits (114), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 22/49 (44%), Positives = 31/49 (63%)
 Frame = +2

Query: 671 NARCFARVEPSHKSKIVEFLQSFDEITAMTGDGVNDAPALKKSEIGIAM 719
           N R FARV P  K  I+  L++   +T M GDG ND  ALK +++G+A+
Sbjct: 257 NTRVFARVAPKQKELIITVLKAQGFVTLMCGDGTNDVGALKHADVGVAL 403
>33697
          Length = 310

 Score = 43.9 bits (102), Expect = 3e-04,   Method: Composition-based stats.
 Identities = 19/34 (55%), Positives = 25/34 (73%)
 Frame = -2

Query: 598 MLDPPRIEVASSVKLCRQAGIRVIMITGDNKGTA 631
           M+DPPR  V  +V  CR AGI+VIM+TGD+  T+
Sbjct: 201 MIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITS 100
>07486
          Length = 763

 Score = 34.7 bits (78), Expect = 0.17,   Method: Composition-based stats.
 Identities = 16/42 (38%), Positives = 29/42 (69%)
 Frame = -1

Query: 709 ALKKSEIGIAMGSGTAVAKTASEMVLADDNFSTIVAAVEEGR 750
           AL ++++GIA+G+GT VA  A+++VL   +   + AA++  R
Sbjct: 742 ALAQADVGIAIGTGTDVAVEAADIVLMKSDLVDVYAAIKLSR 617
>11991
          Length = 881

 Score = 30.8 bits (68), Expect = 3.0,   Method: Compositional matrix adjust.
 Identities = 19/63 (30%), Positives = 30/63 (47%), Gaps = 5/63 (7%)
 Frame = -2

Query: 64  ILLLAACISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAI-----EA 118
           ++L+ ACI F  AW E     I  F   F+I  + +A  I+G     + ++ +     E 
Sbjct: 709 VVLVIACIGFCGAWMESQCMLIMFFTAIFIIFAMEIAVGIIGFIYRDDIDSELNTQLKEG 530

Query: 119 LKE 121
           LKE
Sbjct: 529 LKE 521
>31731
          Length = 579

 Score = 30.4 bits (67), Expect = 4.2,   Method: Composition-based stats.
 Identities = 13/28 (46%), Positives = 20/28 (71%)
 Frame = -1

Query: 70  CISFVLAWFEEGEETITAFVEPFVILLI 97
           CISFVL W  +GE+ I ++   FV+L++
Sbjct: 165 CISFVLNWLIQGEKLIESY-NTFVLLIV 85
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|7549752|ref|NP_036172.1| cullin 1 [Mus musculus]
         (776 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

02265                                                                 631   0.0  
02365                                                                 242   1e-84
33018                                                                  44   3e-04
01055                                                                  30   3.7  
03172                                                                  30   4.9  
>02265
          Length = 1094

 Score =  631 bits (1627), Expect = 0.0,   Method: Compositional matrix adjust.
 Identities = 296/356 (83%), Positives = 327/356 (91%)
 Frame = +3

Query: 79  GGAQFVGLELYKRLKEFLKNYLTNLLKDGEDLMDESVLKFYTQQWEDYRFSSKVLNGICA 138
           GGAQFVG ELYKR+K+FLKNYL NLLKDG+DL+DE VL+FYT+QWEDY+FSSKVL+GICA
Sbjct: 27  GGAQFVGHELYKRMKDFLKNYLVNLLKDGQDLLDEQVLQFYTRQWEDYQFSSKVLDGICA 206

Query: 139 YLNRHWVRRECDEGRKGIYEIYSLALVTWRDCLFRPLNKQVTNAVLKLIEKERNGETINT 198
           YLNRHWVRRECDEG KGIY IYSLAL+TWR+CLF+PLNKQVTNAVLKLIEKERNGETINT
Sbjct: 207 YLNRHWVRRECDEGTKGIYYIYSLALITWRECLFKPLNKQVTNAVLKLIEKERNGETINT 386

Query: 199 RLISGVVQSYVELGLNEDDAFAKGPTLTVYKESFESQFLADTERFYTRESTEFLQQNPVT 258
           RL+SGV+  YVELGLNE+D  AKGPTL VYK+ FE+ FL DTER+YTRESTEFL+QNPVT
Sbjct: 387 RLVSGVINCYVELGLNEEDPSAKGPTLGVYKDHFETPFLDDTERYYTRESTEFLRQNPVT 566

Query: 259 EYMKKAEARLLEEQRRVQVYLHESTQDELARKCEQVLIEKHLEIFHTEFQNLLDADKNED 318
           EYMKKAE RL EEQ+RVQ YLHEST D LA+ CE+VLIEKHLEIFH EFQNLLD DKNED
Sbjct: 567 EYMKKAEMRLKEEQKRVQTYLHESTHDSLAKVCERVLIEKHLEIFHFEFQNLLDTDKNED 746

Query: 319 LGRMYNLVSRIQDGLGELKKLLETHIHNQGLAAIEKCGEAALNDPKMYVQTVLDVHKKYN 378
           LGRMY LVSRI DGLGELK LLE+HIH QGLAAIE+CG+AALNDPK+YVQT+LDVHKKYN
Sbjct: 747 LGRMYMLVSRILDGLGELKTLLESHIHTQGLAAIERCGDAALNDPKVYVQTILDVHKKYN 926

Query: 379 ALVMSAFNNDAGFVAALDKACGRFINNNAVTKMAQSSSKSPELLARYCDSLLKKSS 434
           ALV++AF NDAGFVAALDKACGRFINNN+VTKM  ++SKSPELLARYCD LLKKSS
Sbjct: 927 ALVLTAFVNDAGFVAALDKACGRFINNNSVTKMVNNTSKSPELLARYCDLLLKKSS 1094
>02365
          Length = 1804

 Score =  242 bits (617), Expect(2) = 1e-84,   Method: Compositional matrix adjust.
 Identities = 145/426 (34%), Positives = 232/426 (54%), Gaps = 26/426 (6%)
 Frame = +1

Query: 377 YNALVMSAFNNDAGFVAALDKACGRFINNNAVTKMAQSSSKSPELLARYCDSLLKKSSKN 436
           +N  +  +FN D  F   +      FIN N          KSPE L+ + D  LKK  K 
Sbjct: 529 FNHFLHESFNEDKQFKQMISSGFEHFINLNP---------KSPEYLSLFIDDKLKKGVKG 681

Query: 437 PEEAELEDTLNQVMVVFKYIEDKDVFQKFYAKMLAKRLVHQNSASDDAEASMISKLKQAC 496
             E E+E  L++ MV+F+Y+++KDVF+++Y + LA+RL+   S SDD+E +MISKLK  C
Sbjct: 682 MSEQEIEVVLDKSMVLFRYLQEKDVFERYYKQHLARRLLLNKSGSDDSEKNMISKLKTEC 861

Query: 497 GFEYTSKLQRMFQDIGVSKDLNEQFKKHLTNSEPLDL---DFSIQVLSSGSWPFQQSCTF 553
           G ++TSKL+ MF+D+ VS  +N++FK  +  ++ ++L   + +++VL++G WP Q +   
Sbjct: 862 GCQFTSKLEGMFKDMTVSSGINDEFKASVQQTQVVNLSGVELTVRVLTTGYWPTQSATPI 1041

Query: 554 ALPSELERSYQRFTAFYASRHSGRKLTWLYQLSKGELVTNCF------------------ 595
            +P +   +++ F  FY ++HSGR+LT    L   +L  + F                  
Sbjct: 1042NIPVDPRTAFEAFRRFYLAKHSGRQLTLQPHLGSADLHASFFGQKKDDSADSAAASSSKP 1221

Query: 596 --KNRYTLQASTFQMAILLQYNTEDAYTVQQL-TDSTQIKMDILAXXXXXXXXXXXXXXE 652
               ++ LQ ST+QM ILL +N  D +T +++ T++     +++                
Sbjct: 1222AGPRKHILQVSTYQMCILLLFNNRDKWTFEEIKTETDMPDRELIRALQSLAVGKLAQRVL 1401

Query: 653 DENANVDEVELKPDTLIKLYLGYKNKKLRVNINVPM--KTEQKQEQETTHKNIEEDRKLL 710
            +     E+E  PD +  +   + +K +RV I +    K E + E++ T   ++EDRK  
Sbjct: 1402HKEPKTKEIE--PDHIFTVNDQFTSKLIRVKIQMVASNKGEAEPERKETRNKVDEDRKHE 1575

Query: 711 IQAAIVRIMKMRKVLKHQQLLGEVLTQLSSRFKPRVPVIKKCIDILIEKEYLERVDGEKD 770
           I+AAIVRIMK RK L+H  L+ EV   L  RF P   VIKK I+ LIE+EYL R   ++ 
Sbjct: 1576IEAAIVRIMKARKKLQHNVLVTEVTEMLKPRFLPSPVVIKKRIEGLIEREYLARSQEDRK 1755

Query: 771 TYSYLA 776
            Y+Y+A
Sbjct: 1756IYTYVA 1773

 Score = 90.9 bits (224), Expect(2) = 1e-84,   Method: Compositional matrix adjust.
 Identities = 56/156 (35%), Positives = 90/156 (57%), Gaps = 4/156 (2%)
 Frame = +3

Query: 226 TVYKESFESQFLADTERFYTRESTEFLQQNPVTEYMKKAEARLLEEQRRVQVYLHESTQD 285
           TVY+E FE  FL  +  FY  ES +FL +N  + Y+KK EAR+ EE  R   YL +ST+D
Sbjct: 66  TVYEEDFEKPFLEQSAEFYRLESQKFLAENSASVYIKKVEARINEEAERATHYLDKSTED 245

Query: 286 ELARKCEQVLIEKHL----EIFHTEFQNLLDADKNEDLGRMYNLVSRIQDGLGELKKLLE 341
            + R  E+ LI KH+    E+ ++   ++L+ +K +DL  MY L  R+  GL  + + + 
Sbjct: 246 PVVRVLEEELISKHMKTIVEMENSGVVHMLENNKTDDLACMYKLFFRVVYGLRTMCQCIS 425

Query: 342 THIHNQGLAAIEKCGEAALNDPKMYVQTVLDVHKKY 377
             +  QG A + +  E + N    YVQ++LD++ ++
Sbjct: 426 QFLREQGRALVIEEAEESKN-AITYVQSLLDLNDRF 530
>33018
          Length = 814

 Score = 43.9 bits (102), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 25/100 (25%), Positives = 45/100 (45%)
 Frame = -3

Query: 532 DLDFSIQVLSSGSWPFQQSCTFALPSELERSYQRFTAFYASRHSGRKLTWLYQLSKGELV 591
           DLD S  +LS+  WP  +     LP++L+ S   +T  Y +    R L W   L    + 
Sbjct: 704 DLDISAIILSAQFWPSFREEKITLPAQLQSSLDSYTQQYETLKGNRTLVWKPHLGVMNIE 525

Query: 592 TNCFKNRYTLQASTFQMAILLQYNTEDAYTVQQLTDSTQI 631
                       S  Q A+++Q+  ++ +TV+ L  + ++
Sbjct: 524 LELKDQTLNFSVSPVQAALIMQFQDQNRWTVEDLGQALEM 405
>01055
          Length = 522

 Score = 30.0 bits (66), Expect = 3.7,   Method: Composition-based stats.
 Identities = 13/40 (32%), Positives = 22/40 (55%)
 Frame = -2

Query: 106 DGEDLMDESVLKFYTQQWEDYRFSSKVLNGICAYLNRHWV 145
           +G  +  +S + FY  +W +Y   + + N IC YLN  +V
Sbjct: 521 NGLLMSQDSRMFFYILEWSNYSAPNCLCNCICPYLNEKFV 402
>03172
          Length = 2411

 Score = 29.6 bits (65), Expect = 4.9,   Method: Compositional matrix adjust.
 Identities = 13/39 (33%), Positives = 21/39 (53%)
 Frame = +3

Query: 690  TEQKQEQETTHKNIEEDRKLLIQAAIVRIMKMRKVLKHQ 728
            T Q +  +T H+   EDR + IQA +  + + R  L+ Q
Sbjct: 1422 TRQSEVDKTVHREPREDRLITIQATLANVGQSRSCLQGQ 1538
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|7710014|ref|NP_057925.1| cullin 3 [Mus musculus]
         (768 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

02365                                                                 633   0.0  
02265                                                                 133   3e-31
28450                                                                  29   5.9  
>02365
          Length = 1804

 Score =  633 bits (1632), Expect = 0.0,   Method: Compositional matrix adjust.
 Identities = 311/418 (74%), Positives = 358/418 (85%), Gaps = 1/418 (0%)
 Frame = +1

Query: 352 FDRFLQESFNNDRLFKQTIAGDFEYFLNLNSRSPEYLSLFIDDKLKKGVKGLTEQEVETI 411
           F+ FL ESFN D+ FKQ I+  FE+F+NLN +SPEYLSLFIDDKLKKGVKG++EQE+E +
Sbjct: 529 FNHFLHESFNEDKQFKQMISSGFEHFINLNPKSPEYLSLFIDDKLKKGVKGMSEQEIEVV 708

Query: 412 LDKAMVLFRFMQEKDVFERYYKQHLARRLLTNKSVSDDSEKNMISKLKTECGCQFTSKLE 471
           LDK+MVLFR++QEKDVFERYYKQHLARRLL NKS SDDSEKNMISKLKTECGCQFTSKLE
Sbjct: 709 LDKSMVLFRYLQEKDVFERYYKQHLARRLLLNKSGSDDSEKNMISKLKTECGCQFTSKLE 888

Query: 472 GMFRDMSISNTTMDEFRQHLQATGV-SLGGVDLTVRVLTTGYWPTQSATPKCNIPPAPRH 530
           GMF+DM++S+   DEF+  +Q T V +L GV+LTVRVLTTGYWPTQSATP  NIP  PR 
Sbjct: 889 GMFKDMTVSSGINDEFKASVQQTQVVNLSGVELTVRVLTTGYWPTQSATP-INIPVDPRT 1065

Query: 531 AFEIFRRFYLAKHSGRQLTLQHHMGSADLNATFYGPVKKEDGSEVGVGGAQVTGSNTRKH 590
           AFE FRRFYLAKHSGRQLTLQ H+GSADL+A+F+G  K +         ++  G   RKH
Sbjct: 1066AFEAFRRFYLAKHSGRQLTLQPHLGSADLHASFFGQKKDDSADSAAASSSKPAGP--RKH 1239

Query: 591 ILQVSTFQMTILMLFNNREKYTFEEIQQETDIPERELVRALQSLACGKPTQRVLTKEPKS 650
           ILQVST+QM IL+LFNNR+K+TFEEI+ ETD+P+REL+RALQSLA GK  QRVL KEPK+
Sbjct: 1240ILQVSTYQMCILLLFNNRDKWTFEEIKTETDMPDRELIRALQSLAVGKLAQRVLHKEPKT 1419

Query: 651 KEIESGHIFTVNDQFTSKLHRVKIQTVAAKQGESDPERKETRQKVDDDRKHEIEAAIVRI 710
           KEIE  HIFTVNDQFTSKL RVKIQ VA+ +GE++PERKETR KVD+DRKHEIEAAIVRI
Sbjct: 1420KEIEPDHIFTVNDQFTSKLIRVKIQMVASNKGEAEPERKETRNKVDEDRKHEIEAAIVRI 1599

Query: 711 MKSRKKMQHNVLVAEVTQQLKARFLPSPVVIKKRIEGLIEREYLARTPEDRKVYTYVA 768
           MK+RKK+QHNVLV EVT+ LK RFLPSPVVIKKRIEGLIEREYLAR+ EDRK+YTYVA
Sbjct: 1600MKARKKLQHNVLVTEVTEMLKPRFLPSPVVIKKRIEGLIEREYLARSQEDRKIYTYVA 1773

 Score =  280 bits (715), Expect = 2e-75,   Method: Compositional matrix adjust.
 Identities = 141/211 (66%), Positives = 167/211 (79%), Gaps = 2/211 (0%)
 Frame = +3

Query: 178 VDRGAIRNACQMLMILGLEGRSVYEEDFEAPFLEMSAEFFQMESQKFLAENSASVYIKKV 237
           VDRGA++NACQMLMILG++ R+VYEEDFE PFLE SAEF+++ESQKFLAENSASVYIKKV
Sbjct: 3   VDRGAVKNACQMLMILGIDSRTVYEEDFEKPFLEQSAEFYRLESQKFLAENSASVYIKKV 182

Query: 238 EARINEEIERVMHCLDKSTEEPIVKVVERELISKHMKTIVEMENSGLVHMLKNGKTEDLA 297
           EARINEE ER  H LDKSTE+P+V+V+E ELISKHMKTIVEMENSG+VHML+N KT+DLA
Sbjct: 183 EARINEEAERATHYLDKSTEDPVVRVLEEELISKHMKTIVEMENSGVVHMLENNKTDDLA 362

Query: 298 CMYKLFSRVPNGLKTMCECMSCYLREQGKALVSEEG-EGKNPVDYIQGLLDLKSRFDRFL 356
           CMYKLF RV  GL+TMC+C+S +LREQG+ALV EE  E KN + Y+Q LLDL  RF  F 
Sbjct: 363 CMYKLFFRVVYGLRTMCQCISQFLREQGRALVIEEAEESKNAITYVQSLLDLNDRF*PFP 542

Query: 357 QESFNNDRLFKQTI-AGDFEYFLNLNSRSPE 386
              F       QT+ A DF+    L+   P+
Sbjct: 543 ARVFQRG----QTVQADDFQRL*TLH*PQPQ 623
>02265
          Length = 1094

 Score =  133 bits (334), Expect = 3e-31,   Method: Compositional matrix adjust.
 Identities = 99/356 (27%), Positives = 171/356 (48%), Gaps = 27/356 (7%)
 Frame = +3

Query: 70  GEKLYTGLREVVTEHLINKVREDVLNSLNNNFLQTLNQAWNDHQTAMVMIRDILMYMDRX 129
           G +LY  +++ +  +L+N ++ D  + L+   LQ   + W D+Q +  ++  I  Y++R 
Sbjct: 45  GHELYKRMKDFLKNYLVNLLK-DGQDLLDEQVLQFYTRQWEDYQFSSKVLDGICAYLNRH 221

Query: 130 XXX------XXXXXXXXXLGLIIFRDQVVRYGCIRDHLRQTLLDMIARERKGEVVDRGAI 183
                             L LI +R+ + +   +   +   +L +I +ER GE ++   +
Sbjct: 222 WVRRECDEGTKGIYYIYSLALITWRECLFK--PLNKQVTNAVLKLIEKERNGETINTRLV 395

Query: 184 RNACQMLMILGLEGR---------SVYEEDFEAPFLEMSAEFFQMESQKFLAENSASVYI 234
                  + LGL             VY++ FE PFL+ +  ++  ES +FL +N  + Y+
Sbjct: 396 SGVINCYVELGLNEEDPSAKGPTLGVYKDHFETPFLDDTERYYTRESTEFLRQNPVTEYM 575

Query: 235 KKVEARINEEIERVMHCLDKSTEEPIVKVVERELISKHMKTI-VEMENSGLVHMLKNGKT 293
           KK E R+ EE +RV   L +ST + + KV ER LI KH++    E +N     +L   K 
Sbjct: 576 KKAEMRLKEEQKRVQTYLHESTHDSLAKVCERVLIEKHLEIFHFEFQN-----LLDTDKN 740

Query: 294 EDLACMYKLFSRVPNGLKTMCECMSCYLREQGKALVSEEGEG--KNPVDYIQGLLDLKSR 351
           EDL  MY L SR+ +GL  +   +  ++  QG A +   G+    +P  Y+Q +LD+  +
Sbjct: 741 EDLGRMYMLVSRILDGLGELKTLLESHIHTQGLAAIERCGDAALNDPKVYVQTILDVHKK 920

Query: 352 FDRFLQESFNNDRLFKQTIAGDFEYFLNLN---------SRSPEYLSLFIDDKLKK 398
           ++  +  +F ND  F   +      F+N N         S+SPE L+ + D  LKK
Sbjct: 921 YNALVLTAFVNDAGFVAALDKACGRFINNNSVTKMVNNTSKSPELLARYCDLLLKK 1088
>28450
          Length = 546

 Score = 29.3 bits (64), Expect = 5.9,   Method: Composition-based stats.
 Identities = 12/28 (42%), Positives = 20/28 (71%)
 Frame = +1

Query: 281 NSGLVHMLKNGKTEDLACMYKLFSRVPN 308
           +SG+ +M +N KTE    +++L S+VPN
Sbjct: 295 DSGITYMARNQKTEPAEKIHRLTSKVPN 378
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|82996028|ref|XP_619533.2| PREDICTED: leucyl-tRNA
synthetase isoform 1 [Mus musculus]
         (669 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

15076                                                                 547   0.0  
07453                                                                 117   1e-26
10296                                                                  29   4.9  
>15076
          Length = 2760

 Score =  547 bits (1409), Expect(4) = 0.0,   Method: Compositional matrix adjust.
 Identities = 268/433 (61%), Positives = 318/433 (73%), Gaps = 10/433 (2%)
 Frame = +2

Query: 62  QEHACSRTYGLGTRLPWDEQWLIESLSDSTIYMAFYTVAHLLQGGDLNGQAESPLGIRPQ 121
            EHA SRTYGLGTRLPWD Q+LIESLSDST+YMA+Y VAHLLQGG ++G    P  IRP+
Sbjct: 434 HEHALSRTYGLGTRLPWDSQYLIESLSDSTVYMAYYAVAHLLQGGVVDGSKPGPANIRPE 613

Query: 122 QMTKDVWDYVFFKDAPFPKTQIPKEKLDQLKQEFEFWYPVDLRASGKDLIPNHLSYYIYN 181
           Q+T +VWDY+F +   +PK  IPK  LD L+ EF +WYPVD+R SGKDLI NHL+Y+IY 
Sbjct: 614 QLTLEVWDYIFTQTDNYPKCDIPKSTLDLLRSEFSYWYPVDVRMSGKDLIQNHLTYFIYC 793

Query: 182 HVAMWPEQSDKWPVSVRANGHLLLNSEKMSKSTGNFLTLSQAVDKFSADGMRLALADAGD 241
           H AMWP    KWP  +RANGH+LLNSEKMSKSTGNFLTL  AVDKFSADGMR +LADAGD
Sbjct: 794 HTAMWPNDKSKWPKGIRANGHILLNSEKMSKSTGNFLTLYDAVDKFSADGMRFSLADAGD 973

Query: 242 TVEDANFVEAMADAGILRLYTWVEWVKEMLASCSSLRSGPAD--SFNDRVFASEMNAGII 299
           TVEDANFVE MADAG+LRLYT +EWV+EM A   SLRSGP    +FNDRVF SE+N  I+
Sbjct: 974 TVEDANFVEKMADAGLLRLYTLLEWVREMAAQRDSLRSGPPKDYTFNDRVFLSEINKTIL 1153

Query: 300 KTDQNYEKMMFKEALKTGFFEFQAAKDKYRELATEGMHRELVFRFIEVQTILLTPFCPHL 359
           +T Q+Y+  MFKEAL+TG FEFQ  +DKYRE+ ++GMHR+LV RFIEVQ +L+ P CPH+
Sbjct: 1154ETQQHYDNFMFKEALRTGVFEFQGKRDKYREVESQGMHRDLVLRFIEVQALLMAPICPHM 1333

Query: 360 CEHIWTLLGK------PDSIMHASWPVA--GPVDESLIRSSQYLMEVAHDLRLRLKNYMM 411
            EHIW  L K       +SIMHA+WP      VDE LIRSS YLM+ AH+ RLRLK  + 
Sbjct: 1334AEHIWGELQKMQTGSTGZSIMHATWPQVKESDVDELLIRSSDYLMDAAHEFRLRLKTVLH 1513

Query: 412 PAKGKKTDKQPAQRPSHCTIYVAKNYPVWQHITLTTLRSHFEANNGKLPDNKVIASELGS 471
           P K KK     A  P+H TI+VA+ YP WQ+  LTTL+  F AN G  PDNKVI+SEL  
Sbjct: 1514PGKNKK-----ATPPTHGTIWVARTYPPWQNAVLTTLKELFTANQG-FPDNKVISSELMK 1675

Query: 472 LPELKKYMKKVMP 484
             + +   +K  P
Sbjct: 1676KTDCRST*RKSCP 1714

 Score =  105 bits (263), Expect(4) = 0.0,   Method: Compositional matrix adjust.
 Identities = 54/130 (41%), Positives = 77/130 (59%), Gaps = 1/130 (0%)
 Frame = +1

Query: 540  KVREECCPGKPLNVFRTEPGVPVSLVNPQPSSGHFSTKIDIRQGDSCESIIRRLMKTDRG 599
            +VR++CCPGKP   +RTEP V +  VN Q  SG F   + +  GD    +  RLMK++R 
Sbjct: 1876 EVRDDCCPGKPFISYRTEPSVCLRFVNQQQCSGLFEVSVPVFDGDVTSKLAARLMKSERS 2055

Query: 600  -IKDLSKVKLMRFDDPLLGPRRVPVLGREHSEKTLISENAVFHVDLVSKKVHLTENGLRT 658
             IKD+S VKL+R+ D   G R +P L     +   +S +AVFH+D+ +  V + ENG   
Sbjct: 2056 KIKDVSSVKLLRYKDAEAGWRSIPELNGSGDKNVAMSASAVFHIDVQNNTVTVQENGSPV 2235

Query: 659  DIGDTMVYLV 668
             +G  MVY+V
Sbjct: 2236 PLGRQMVYMV 2265

 Score = 87.4 bits (215), Expect(4) = 0.0,   Method: Compositional matrix adjust.
 Identities = 36/58 (62%), Positives = 46/58 (79%)
 Frame = +3

Query: 2   EPEKQVMSRSADECVVALCDQWYLDYGDENWKKQTFQCLKNMETFCEESRKNFEASLD 59
           EPE QV+SRS DECVVALCDQW+LDYG+ +W+K+  +CL  + TF E+ R NF A+LD
Sbjct: 252 EPENQVISRSGDECVVALCDQWFLDYGEASWRKEADECLAGLNTFSEDVRHNFTATLD 425

 Score = 49.3 bits (116), Expect(4) = 0.0,   Method: Compositional matrix adjust.
 Identities = 23/47 (48%), Positives = 33/47 (70%)
 Frame = +3

Query: 487  AMIKENMEKKGPRVLDLELEFDEQAVLMENIVYLTNSLELEHIEVKF 533
            A  + N  K G R LDL  EFDE+ VL  ++VYL+N+LELE ++++F
Sbjct: 1719 ASCQGNFSKHGQRALDLTSEFDEKQVLETSLVYLSNTLELEGLDIRF 1859

 Score = 28.9 bits (63), Expect = 6.2,   Method: Compositional matrix adjust.
 Identities = 13/18 (72%), Positives = 15/18 (83%)
 Frame = +1

Query: 475  LKKYMKKVMPFVAMIKEN 492
            L+KYMKKVMPFV + KE 
Sbjct: 1684 LQKYMKKVMPFVQVAKET 1737
>07453
          Length = 510

 Score =  117 bits (294), Expect = 1e-26,   Method: Composition-based stats.
 Identities = 56/72 (77%), Positives = 59/72 (81%)
 Frame = -3

Query: 187 PEQSDKWPVSVRANGHLLLNSEKMSKSTGNFLTLSQAVDKFSADGMRLALADAGDTVEDA 246
           P    KWP  +RANGH+LLNSEKMSKSTGNFLTL  AVDKFSADGMR +LADAGDTVEDA
Sbjct: 508 PNDKSKWPKGIRANGHILLNSEKMSKSTGNFLTLYDAVDKFSADGMRFSLADAGDTVEDA 329

Query: 247 NFVEAMADAGIL 258
           NFVE MAD   L
Sbjct: 328 NFVEKMADLSAL 293

 Score = 79.3 bits (194), Expect(2) = 4e-22,   Method: Compositional matrix adjust.
 Identities = 37/65 (56%), Positives = 51/65 (78%)
 Frame = -3

Query: 474 ELKKYMKKVMPFVAMIKENMEKKGPRVLDLELEFDEQAVLMENIVYLTNSLELEHIEVKF 533
           EL+KYMKKVMPFV + KEN  K G R LDL  EFDE+ VL  ++VYL+N+LELE ++++F
Sbjct: 196 ELQKYMKKVMPFVQVAKENFSKHGQRALDLTSEFDEKQVLETSLVYLSNTLELEGLDIRF 17

Query: 534 ASEAE 538
           + +A+
Sbjct: 16  SEDAD 2

 Score = 44.3 bits (103), Expect(2) = 4e-22,   Method: Compositional matrix adjust.
 Identities = 21/35 (60%), Positives = 25/35 (71%)
 Frame = -1

Query: 435 KNYPVWQHITLTTLRSHFEANNGKLPDNKVIASEL 469
           + YP WQ+  LTTL+  F AN G  PDNKVI+SEL
Sbjct: 309 RTYPPWQNAVLTTLKELFTANQG-FPDNKVISSEL 208
>10296
          Length = 1682

 Score = 29.3 bits (64), Expect = 4.9,   Method: Compositional matrix adjust.
 Identities = 24/74 (32%), Positives = 32/74 (43%)
 Frame = +2

Query: 493  MEKKGPRVLDLELEFDEQAVLMENIVYLTNSLELEHIEVKFASEAEDKVREECCPGKPLN 552
            +E++ PRV      F  QA+ +     ++N LEL        S  E   R  CC  +PL 
Sbjct: 1145 LEQETPRVKSHVARFGAQALALG----VSNLLELAA-----PSSMECTTRSSCCVYRPLT 1297

Query: 553  VFRTEPGVPVSLVN 566
              RT  G   SLV 
Sbjct: 1298 ASRTSSG*LGSLVT 1339
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|8394027|ref|NP_058587.1| alpha isoform of regulatory
subunit A, protein phosphatase 2 [Mus musculus]
         (589 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

26856                                                                 829   0.0  
01469                                                                  46   4e-05
25614                                                                  41   0.001
30928                                                                  31   1.2  
14913                                                                  31   1.6  
36681                                                                  28   8.2  
09672                                                                  28   8.5  
>26856
          Length = 2013

 Score =  829 bits (2141), Expect = 0.0,   Method: Compositional matrix adjust.
 Identities = 401/517 (77%), Positives = 453/517 (87%)
 Frame = +1

Query: 73  LGTFTTLVGGPEYVHCLLPPLESLATVEETVVRDKAVESLRAISHEHSPSDLEAHFVPLV 132
           LG FT LVGGP     L   LESLATVEETVVRDKAV+SLR I+ +HS SDLEAHFVPLV
Sbjct: 13  LGIFTPLVGGPRTCTLLTAALESLATVEETVVRDKAVDSLRNIAAQHSXSDLEAHFVPLV 192

Query: 133 KRLAGGDWFTSRTSACGLFSVCYPRVSSAVKAELRQYFRNLCSDDTPMVRRAAASKLGEF 192
           KRL+ GDWFTSRTSACGLF+ CY RV+S+VKA+LRQ FRNLCSDDTPMVRRAAA KLGEF
Sbjct: 193 KRLSTGDWFTSRTSACGLFACCYARVASSVKADLRQLFRNLCSDDTPMVRRAAAGKLGEF 372

Query: 193 AKVLELDNVKSEIIPMFSNLASDEQDSVRLLAVEACVNIAQLLPQEDLEALVMPTLRQAA 252
           AK +E + +KS++IP+F+ LA DEQDSVRLLAVEACV+IA LLP ED E LVMPTLRQA+
Sbjct: 373 AKEVESEFLKSDLIPLFAMLAQDEQDSVRLLAVEACVSIASLLPSEDTEQLVMPTLRQAS 552

Query: 253 EDKSWRVRYMVADKFTELQKAVGPEITKTDLVPAFQNLMKDCEAEVRAAASHKVKEFCEN 312
           EDKSWRVRYMVADKFTELQKAVGPEITK DLVPAFQ+L+KDCEAEVRAA+++KVK+FC+ 
Sbjct: 553 EDKSWRVRYMVADKFTELQKAVGPEITKNDLVPAFQSLLKDCEAEVRAASANKVKDFCQA 732

Query: 313 LSADCRENVIMTQILPCIKELVSDANQHVKSALASVIMGLSPILGKDNTIEHLLPLFLAQ 372
           LS D RE +IMT ILPC+K+LV+DANQHVKSALASVIMGLSPILGKDNTIEHLLPLFL+Q
Sbjct: 733 LSPDVRETIIMTNILPCVKDLVADANQHVKSALASVIMGLSPILGKDNTIEHLLPLFLSQ 912

Query: 373 LKDECPEVRLNIISNLDCVNEVIGIRQLSQSLLPAIVELAEDAKWRVRLAIIEYMPLLAG 432
           LKDECP+VRLNIISNLDCVNEVIGI+QLSQSLLPAIVELAED KWRVRLAIIEYMPLLAG
Sbjct: 913 LKDECPDVRLNIISNLDCVNEVIGIKQLSQSLLPAIVELAEDTKWRVRLAIIEYMPLLAG 1092

Query: 433 QLGVEFFDEKLNSLCMAWLVDHVYAIREAATSNLKKLVEKFGKEWAHATIIPKVLAMSGD 492
           QLGV+FFDEKLNSLCM WLVDHV+AIREAAT NLKKLVEKFG EWA  T+IPKV +MS D
Sbjct: 1093QLGVQFFDEKLNSLCMTWLVDHVFAIREAATLNLKKLVEKFGPEWAQETVIPKVTSMSKD 1272

Query: 493 PNYLHRMTTLFCINVLSEVCGQDITTKHMLPTVLRMAGDPVANVRFNVAKSLQKIGPILD 552
            NYLHRMT LF IN+L+E  GQ++T+K +LPT   +A D V NVRFN AK+LQKI P+LD
Sbjct: 1273SNYLHRMTCLFSINLLAETMGQELTSKLLLPTRF-LARDTVPNVRFNAAKTLQKIAPLLD 1449

Query: 553 NSTLQSEVKPILEKLTQDQDVDVKYFAQEALTVLSLA 589
            ST+QS+VKPILE L  D D+DV++FA +AL V+ + 
Sbjct: 1450QSTVQSQVKPILETLKSDSDIDVQFFAADALDVIGVG 1560

 Score = 65.1 bits (157), Expect = 7e-11,   Method: Compositional matrix adjust.
 Identities = 92/402 (22%), Positives = 159/402 (39%), Gaps = 48/402 (11%)
 Frame = +1

Query: 68  ALAEQLGTFTTLVGGPEYVHCLLPPLESLATVEETVVRDKAVESLRAISHEHSPSDLEAH 127
           A A +LG F   V        L+P    LA  E+  VR  AVE+  +I+      D E  
Sbjct: 346 AAAGKLGEFAKEVESEFLKSDLIPLFAMLAQDEQDSVRLLAVEACVSIASLLPSEDTEQL 525

Query: 128 FVPLVK----------RLAGGDWFTSRTSACG--------------LFSVCYPRVSSAVK 163
            +P ++          R    D FT    A G              L   C   V +A  
Sbjct: 526 VMPTLRQASEDKSWRVRYMVADKFTELQKAVGPEITKNDLVPAFQSLLKDCEAEVRAASA 705

Query: 164 AELRQY--------------------FRNLCSDDTPMVRRAAASKLGEFAKVLELDNVKS 203
            +++ +                     ++L +D    V+ A AS +   + +L  DN   
Sbjct: 706 NKVKDFCQALSPDVRETIIMTNILPCVKDLVADANQHVKSALASVIMGLSPILGKDNTIE 885

Query: 204 EIIPMFSNLASDEQDSVRLLAVEA--CVNIAQLLPQEDLEALVMPTLRQAAEDKSWRVRY 261
            ++P+F +   DE   VRL  +    CVN  +++  + L   ++P + + AED  WRVR 
Sbjct: 886 HLLPLFLSQLKDECPDVRLNIISNLDCVN--EVIGIKQLSQSLLPAIVELAEDTKWRVRL 1059

Query: 262 MVADKFTELQKAVGPEITKTDLVPAFQNLMKDCEAEVRAAASHKVKEFCENLSADCRENV 321
            + +    L   +G +     L       + D    +R AA+  +K+  E    +  +  
Sbjct: 1060AIIEYMPLLAGQLGVQFFDEKLNSLCMTWLVDHVFAIREAATLNLKKLVEKFGPEWAQET 1239

Query: 322 IMTQILPCIKELVSDANQ-HVKSALASVIMGLSPILGKDNTIEHLLPL-FLAQLKDECPE 379
               ++P +  +  D+N  H  + L S+ + L+  +G++ T + LLP  FLA  +D  P 
Sbjct: 1240----VIPKVTSMSKDSNYLHRMTCLFSINL-LAETMGQELTSKLLLPTRFLA--RDTVPN 1398

Query: 380 VRLNIISNLDCVNEVIGIRQLSQSLLPAIVELAEDAKWRVRL 421
           VR N    L  +  ++    +   + P +  L  D+   V+ 
Sbjct: 1399VRFNAAKTLQKIAPLLDQSTVQSQVKPILETLKSDSDIDVQF 1524

 Score = 51.6 bits (122), Expect = 9e-07,   Method: Compositional matrix adjust.
 Identities = 50/220 (22%), Positives = 94/220 (42%), Gaps = 5/220 (2%)
 Frame = +1

Query: 13   IAVLIDELRNEDVQLRLNSIKKLSTIALALGVERTRSELLPFLTDTIYDED-EVLLALAE 71
            + + + +L++E   +RLN I  L  +   +G+++    LLP + +   D    V LA+ E
Sbjct: 892  LPLFLSQLKDECPDVRLNIISNLDCVNEVIGIKQLSQSLLPAIVELAEDTKWRVRLAIIE 1071

Query: 72   QLGTFTTLVGGPEYVHCLLPPLESLATV----EETVVRDKAVESLRAISHEHSPSDLEAH 127
                +  L+ G   V      L SL           +R+ A  +L+ +  +  P   +  
Sbjct: 1072 ----YMPLLAGQLGVQFFDEKLNSLCMTWLVDHVFAIREAATLNLKKLVEKFGPEWAQET 1239

Query: 128  FVPLVKRLAGGDWFTSRTSACGLFSVCYPRVSSAVKAELRQYFRNLCSDDTPMVRRAAAS 187
             +P V  ++    +  R +     ++    +   + ++L    R L  D  P VR  AA 
Sbjct: 1240 VIPKVTSMSKDSNYLHRMTCLFSINLLAETMGQELTSKLLLPTRFLARDTVPNVRFNAAK 1419

Query: 188  KLGEFAKVLELDNVKSEIIPMFSNLASDEQDSVRLLAVEA 227
             L + A +L+   V+S++ P+   L SD    V+  A +A
Sbjct: 1420 TLQKIAPLLDQSTVQSQVKPILETLKSDSDIDVQFFAADA 1539
>01469
          Length = 2023

 Score = 46.2 bits (108), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 37/138 (26%), Positives = 61/138 (44%), Gaps = 3/138 (2%)
 Frame = +1

Query: 247 TLRQAAEDKSWRVRYMVADKFTELQKAVGPEITKTDLVPAFQNLMKDCEAEVRAAASHKV 306
           TL QA +   W+VR  +A    E+    G  IT  DL+P F   +KD + EVR      +
Sbjct: 454 TLAQAMQ---WKVRRTLAFSIHEMALIEGEAITHNDLLPVFDGFIKDLD-EVRIGVLKHL 621

Query: 307 KEFCENLSADCRENVIMTQILPCIKELVSDANQ---HVKSALASVIMGLSPILGKDNTIE 363
            +F   L  + R+     Q L  + + +   N      +  L+  ++ L  +    + + 
Sbjct: 622 ADFLRLLRPNVRQ-----QYLAKVSDFMKTDNHRNWRFRKELSEQLIYLCELFDPRSIVR 786

Query: 364 HLLPLFLAQLKDECPEVR 381
           H+ PL +A   D+  EVR
Sbjct: 787 HICPLAVALCMDKVAEVR 840

 Score = 38.1 bits (87), Expect = 0.011,   Method: Compositional matrix adjust.
 Identities = 67/276 (24%), Positives = 121/276 (43%), Gaps = 23/276 (8%)
 Frame = +1

Query: 329 CIKELVSDANQ----HVKSALASVIMGLSPILGKDNTIEHLLPLFLAQLKDECPEVRLNI 384
           CIK L     Q     V+  LA  I  ++ I G+  T   LLP+F   +KD   EVR+ +
Sbjct: 433 CIKHLYETLAQAMQWKVRRTLAFSIHEMALIEGEAITHNDLLPVFDGFIKD-LDEVRIGV 609

Query: 385 ISNLDCVNEVI--GIRQLSQSLLPAIVELAEDAKWRVRLAIIEYMPLLAGQLGVEFFDEK 442
           + +L     ++   +RQ   + +   ++      WR R  + E +  L      E FD +
Sbjct: 610 LKHLADFLRLLRPNVRQQYLAKVSDFMKTDNHRNWRFRKELSEQLIYLC-----ELFDPR 774

Query: 443 -----LNSLCMAWLVDHVYAIREAATSNLKKLVEKFGKEWAHATIIPKVLAMSGDPNYLH 497
                +  L +A  +D V  +R A +  L   V +   E     ++  + +   D   L+
Sbjct: 775 SIVRHICPLAVALCMDKVAEVR-AVSFGLMSAVLRRVHEEGEDKLLQVICSDLSDQFALN 951

Query: 498 ------RMTTLFCINVLSE-VCGQDITTKHMLPTVLRMAGDPVANVRFNVAKSL-QKIGP 549
                 ++    C+ VL++      +  + +LP +L +  D + NVR  +AK L Q++ P
Sbjct: 952 IKWLGRQIYCQMCLVVLADNAVPPPVFAELLLPGLLALGTDAIPNVRLTLAKVLAQRVAP 1131

Query: 550 ILDNSTLQSEVK----PILEKLTQDQDVDVKYFAQE 581
           +   ++ Q+         L+ L  D+D DV+YF+ +
Sbjct: 1132LDYFTSSQNPCHEALLTTLQALKTDKDQDVRYFSSQ 1239
>25614
          Length = 433

 Score = 41.2 bits (95), Expect = 0.001,   Method: Composition-based stats.
 Identities = 35/116 (30%), Positives = 48/116 (41%)
 Frame = -2

Query: 365 LLPLFLAQLKDECPEVRLNIISNLDCVNEVIGIRQLSQSLLPAIVELAEDAKWRVRLAII 424
           LLP F   L D    VR    +N   V  V+G +   + LLP +  L ED  W VR A  
Sbjct: 408 LLPRFSQMLTDPLFHVRKVCAANFGEVCSVVGKQSSEELLLPKLNSLCEDGVWGVRKACA 229

Query: 425 EYMPLLAGQLGVEFFDEKLNSLCMAWLVDHVYAIREAATSNLKKLVEKFGKEWAHA 480
           E    ++    +E     L  L +  L D    +R +A  +L   +  F    AHA
Sbjct: 228 ECFMAISCACSLETRRGYLARLFVHLLADQSRWVRMSAFQHLGPFISTF----AHA 73

 Score = 30.8 bits (68), Expect = 1.5,   Method: Composition-based stats.
 Identities = 19/101 (18%), Positives = 44/101 (43%)
 Frame = -2

Query: 451 LVDHVYAIREAATSNLKKLVEKFGKEWAHATIIPKVLAMSGDPNYLHRMTTLFCINVLSE 510
           L D ++ +R+   +N  ++    GK+ +   ++PK+ ++  D  +  R     C   +S 
Sbjct: 384 LTDPLFHVRKVCAANFGEVCSVVGKQSSEELLLPKLNSLCEDGVWGVRKACAECFMAISC 205

Query: 511 VCGQDITTKHMLPTVLRMAGDPVANVRFNVAKSLQKIGPIL 551
            C  +    ++    + +  D    VR +   + Q +GP +
Sbjct: 204 ACSLETRRGYLARLFVHLLADQSRWVRMS---AFQHLGPFI 91
>30928
          Length = 343

 Score = 31.2 bits (69), Expect = 1.2,   Method: Composition-based stats.
 Identities = 18/57 (31%), Positives = 28/57 (49%)
 Frame = +2

Query: 205 IIPMFSNLASDEQDSVRLLAVEACVNIAQLLPQEDLEALVMPTLRQAAEDKSWRVRY 261
           I+P      +DE + VR  A+ A   I        +E L++P L +   D +WR+RY
Sbjct: 89  ILPSILQALADESEFVRDTALRAGQRIISQYADTAIE-LLLPELERGLFDDNWRIRY 256
>14913
          Length = 1174

 Score = 30.8 bits (68), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 24/88 (27%), Positives = 46/88 (52%), Gaps = 6/88 (6%)
 Frame = -3

Query: 128 FVPLVKRLAGGDWFTSRTSACGLFSVCYPRVSSAVKAELRQ-YFRNLC---SDDTPMVRR 183
            +P+V++    D    R ++    +V     +  V ++L +   +++C   +D  PMVR 
Sbjct: 272 LMPMVEKCMTSDKGKERRASYLAMAVVVEGCADYVMSKLMKVMLQSVCQGLNDSEPMVRN 93

Query: 184 AAASKLGEFAKVLELDNVK--SEIIPMF 209
           AA   LG+F++ L+ D  K  SE++P+ 
Sbjct: 92  AALFALGQFSEHLQPDITKFASELLPLL 9
>36681
          Length = 1210

 Score = 28.5 bits (62), Expect = 8.2,   Method: Compositional matrix adjust.
 Identities = 26/67 (38%), Positives = 34/67 (50%), Gaps = 7/67 (10%)
 Frame = -3

Query: 78  TLVGGP-----EYVHCLLPPLESLATVEETVVRDKAVESLRAISHEHS--PSDLEAHFVP 130
           +LV GP      YV   LP  + L       V+ + VESL ++ H HS  P+ +E HF  
Sbjct: 227 SLVPGPFYHDARYVGVRLP-FQHLGIDMADHVQVERVESLGSVEHNHSFVPNCIEQHF-- 57

Query: 131 LVKRLAG 137
            V RLAG
Sbjct: 56  -VCRLAG 39
>09672
          Length = 1963

 Score = 28.5 bits (62), Expect = 8.5,   Method: Compositional matrix adjust.
 Identities = 22/78 (28%), Positives = 36/78 (46%), Gaps = 6/78 (7%)
 Frame = -2

Query: 310  CENLSADCRENVIMTQILPCIKELVSDANQHVKSALASVIMGLSPIL-GKDN-----TIE 363
            C  L A C E+ ++  +LP +KE +  A+   + A    +M    IL G D+      +E
Sbjct: 1959 CLMLMATCCEDDVVPHVLPFVKENIRHADWRYRDA---AVMAFGSILEGPDSEKLKPIVE 1789

Query: 364  HLLPLFLAQLKDECPEVR 381
              +P+ +  L D    VR
Sbjct: 1788 QAMPMLIELLTDPSVVVR 1735
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|88014720|ref|NP_032405.3| karyopherin (importin) beta
1 [Mus musculus]
         (876 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

09672                                                                 763   0.0  
26856                                                                  30   4.2  
15415                                                                  30   4.6  
10618                                                                  29   7.8  
>09672
          Length = 1963

 Score =  763 bits (1971), Expect = 0.0,   Method: Compositional matrix adjust.
 Identities = 365/526 (69%), Positives = 440/526 (83%), Gaps = 1/526 (0%)
 Frame = -2

Query: 350  VCLMLLSTCCEDDIVPHVLPFIKEHIKNPDWRYRDAAVMAFGSILEGPEPNQLKPLVIQA 409
            VCLML++TCCEDD+VPHVLPF+KE+I++ DWRYRDAAVMAFGSILEGP+  +LKP+V QA
Sbjct: 1962 VCLMLMATCCEDDVVPHVLPFVKENIRHADWRYRDAAVMAFGSILEGPDSEKLKPIVEQA 1783

Query: 410  MPTLIELMKDPSVVVRDTTAWTVGRICELLPEAAINDVYLAPLLQCLIEGLSAEPRVASN 469
            MP LIEL+ DPSVVVRDT AWTVGR+CE+LPEA IN+  L PLL  LI+GL AEPRVASN
Sbjct: 1782 MPMLIELLTDPSVVVRDTAAWTVGRVCEMLPEAVINENCLNPLLGALIKGLEAEPRVASN 1603

Query: 470  VCWAFSSLXXXXXXXXXXXXXXXXXXTYCLSSSFELIVQKLLETTDRPDGHQNNLRSSAY 529
            +CWAFSSL                  TYCLSS FE +VQ+LLETTDR DG+Q+NLR++AY
Sbjct: 1602 ICWAFSSLAEAAYESADTADEISEPETYCLSSYFETMVQRLLETTDRTDGNQHNLRNAAY 1423

Query: 530  ESLMEIVKNSAKDCYPAVQKTTLVIMERLQQVLQMESHIQSTSDRIQFNDLQSLLCATLQ 589
            E+LME+VKNS KDCY  VQKTT++I+ERL++VL ME+ IQST+DR+Q+NDLQSLLCATLQ
Sbjct: 1422 EALMELVKNSPKDCYLIVQKTTVIILERLERVLGMEAAIQSTNDRVQYNDLQSLLCATLQ 1243

Query: 590  NVLRKVQHQDALQISDVVMASLLRMFQSTAG-SGGVQEDALMAVSTLVEVLGGEFLKYME 648
            +V+RK+  +DA +ISD +M SLL MFQ+T+G +G VQEDAL+AVSTL EVLG  F KY+E
Sbjct: 1242 SVVRKMTPEDAPKISDQIMTSLLSMFQNTSGKAGNVQEDALVAVSTLCEVLGDNFEKYLE 1063

Query: 649  AFKPFLGIGLKNYAEYQVCLAAVGLVGDLCRALQSNILPFCDEVMQLLLENLGNENVHRS 708
            AFKP+L +GLKNYAEYQVCLAAVGL+GD+CRAL   +LPFC+E+M +LL+NLGNE+VHRS
Sbjct: 1062 AFKPYLLVGLKNYAEYQVCLAAVGLIGDMCRALGLKMLPFCNELMMVLLDNLGNESVHRS 883

Query: 709  VKPQILSVFGDIALAIGGEFKKYLEVVLNTLQQASQAQVDKSDFDMVDYLNELRESCLEA 768
            VKPQILSVFGD+ALAIG  FK YLEVVL TLQQASQAQVDK+D+DM+DYLNELRE CLEA
Sbjct: 882  VKPQILSVFGDVALAIGPNFKPYLEVVLTTLQQASQAQVDKTDYDMIDYLNELREGCLEA 703

Query: 769  YTGIVQGLKGDQENVHPDVMLVQPRVEFILSFIDHIAGDEDHTDGVVACAAGLIGDLCTA 828
            YTGIVQGLKGD E + PDV L+QP V  I+SFI+HI+ DED +D  +A   GL+GDLCTA
Sbjct: 702  YTGIVQGLKGDAEVLSPDVNLLQPHVAHIISFIEHISMDEDKSDSNIAACCGLLGDLCTA 523

Query: 829  FGKDVLKLVEARPMIHELLTEGRRSKTNKAKTLATWATKELRKLKN 874
            F   ++ ++E + +I  LLT+GRRSK  KAKTLATWATKE+RK+KN
Sbjct: 522  FSMSIMPMLE-KDVIQNLLTQGRRSKVQKAKTLATWATKEIRKMKN 388
>26856
          Length = 2013

 Score = 30.0 bits (66), Expect = 4.2,   Method: Compositional matrix adjust.
 Identities = 43/216 (19%), Positives = 80/216 (37%)
 Frame = +1

Query: 241 LVKIMSLYYQYMETYMGPALFAITIEAMKSDIDEVALQGIEFWSNVCDEEMDLAIEASEA 300
           LVK +S    +        LFA     + S +     Q    + N+C ++  +   A+  
Sbjct: 187 LVKRLSTGDWFTSRTSACGLFACCYARVASSVKADLRQ---LFRNLCSDDTPMVRRAA-- 351

Query: 301 AEQGRPPEHTSKFYAKGALQYLVPILTQTLTKQDENXXXXXWNPCKAAGVCLMLLSTCCE 360
              G+  E   +  ++     L+P+    +  QDE           A   C+ + S    
Sbjct: 352 --AGKLGEFAKEVESEFLKSDLIPLFA--MLAQDEQDSVRLL----AVEACVSIASLLPS 507

Query: 361 DDIVPHVLPFIKEHIKNPDWRYRDAAVMAFGSILEGPEPNQLKPLVIQAMPTLIELMKDP 420
           +D    V+P +++  ++  WR R      F  + +   P   K  ++   P    L+KD 
Sbjct: 508 EDTEQLVMPTLRQASEDKSWRVRYMVADKFTELQKAVGPEITKNDLV---PAFQSLLKDC 678

Query: 421 SVVVRDTTAWTVGRICELLPEAAINDVYLAPLLQCL 456
              VR  +A  V   C+ L       + +  +L C+
Sbjct: 679 EAEVRAASANKVKDFCQALSPDVRETIIMTNILPCV 786
>15415
          Length = 392

 Score = 30.0 bits (66), Expect = 4.6,   Method: Composition-based stats.
 Identities = 16/45 (35%), Positives = 25/45 (55%)
 Frame = +1

Query: 653 FLGIGLKNYAEYQVCLAAVGLVGDLCRALQSNILPFCDEVMQLLL 697
           F  +G+ +Y E  + +  VG       A QSNI+PF D  +++LL
Sbjct: 166 FF*LGINSYPEMSISMDIVGET----EATQSNIIPFTDVNLRVLL 288
>10618
          Length = 906

 Score = 29.3 bits (64), Expect = 7.8,   Method: Compositional matrix adjust.
 Identities = 19/71 (26%), Positives = 32/71 (45%), Gaps = 10/71 (14%)
 Frame = -2

Query: 106 PSSASQCVAGIA--------CAEIPV--SQWPELIPQLVANVTNPNSTEHMKESTLEAIG 155
           PS  S CV  +         CAEIPV   QW ++    +A V    +  +  E   +++ 
Sbjct: 668 PSFQSGCVKILGMT*KHTAMCAEIPVMCRQWVKMSSSFMAKVCPQKTVLNFSEKAFKSL* 489

Query: 156 YICQDIDPEQL 166
            +C+ ID  ++
Sbjct: 488 KVCKFIDENRV 456
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|9790069|ref|NP_062667.1| HLA-B-associated transcript
1A [Mus musculus]
         (428 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

09316                                                                 756   0.0  
01062                                                                 256   9e-69
00621                                                                 173   2e-43
02498                                                                  97   1e-41
07310                                                                 142   3e-34
02054                                                                 105   4e-34
01517                                                                 125   2e-29
00739                                                                 125   5e-29
00162                                                                 121   4e-28
19525                                                                 101   7e-22
08036                                                                  68   6e-19
09327                                                                  91   1e-18
33543                                                                  90   2e-18
04883                                                                  87   9e-18
31899                                                                  83   2e-16
14337                                                                  83   3e-16
34295                                                                  81   7e-16
03336                                                                  78   7e-15
00617                                                                  75   5e-14
19640                                                                  73   2e-13
11624                                                                  69   2e-12
19151                                                                  69   3e-12
10649                                                                  65   4e-11
12995                                                                  63   3e-10
11160                                                                  58   9e-09
33025                                                                  56   3e-08
39583                                                                  52   4e-07
03381                                                                  49   4e-06
31220                                                                  45   7e-05
19172                                                                  42   5e-04
06438                                                                  42   6e-04
33083                                                                  41   0.001
12121                                                                  35   0.047
11423                                                                  35   0.070
02305                                                                  29   3.3  
>09316
          Length = 2312

 Score =  756 bits (1952), Expect(2) = 0.0,   Method: Compositional matrix adjust.
 Identities = 360/407 (88%), Positives = 384/407 (94%)
 Frame = +2

Query: 19   ETAAGADGTEAPAKKDVKGSYVSIHSSGFRDFLLKPELLRAIVDCGFEHPSEVQHECIPQ 78
            ETA    G E  AKKDVKG+YVSIHSSGFRDFLLKPELLRAI+DCGFEHPSEVQHECIPQ
Sbjct: 767  ETAVDGAGGEGQAKKDVKGTYVSIHSSGFRDFLLKPELLRAIIDCGFEHPSEVQHECIPQ 946

Query: 79   AILGMDVLCQAKSGMGKTAVFVLATLQQLEPVTGQVSVLVMCHTRELAFQISKEYERFSK 138
            AIL MDVLCQAKSGMGKTAVFVLATLQQLEPV GQVSVLVM HTRELAFQISKEYERFSK
Sbjct: 947  AILSMDVLCQAKSGMGKTAVFVLATLQQLEPVDGQVSVLVMAHTRELAFQISKEYERFSK 1126

Query: 139  YMPNVKVAVFFGGLSIKKDEEVLKKNCPHIVVGTPGRILALARNKSLNLKHIKHFILDEC 198
            YM NVK+AVFFGG+S+KKDEEVL KNCPHIVVGTPGR+ ALA+  +LNLK IKHFILDEC
Sbjct: 1127 YMNNVKIAVFFGGMSVKKDEEVLSKNCPHIVVGTPGRLHALAKANNLNLKKIKHFILDEC 1306

Query: 199  DKMLEQLDMRRDVQEIFRMTPHEKQVMMFSATLSKEIRPVCRKFMQDPMEIFVDDETKLT 258
            DKML  LDMRRDVQEIFR+TPHEKQVMMFSATLSKEIRP+C+KFMQDPME++VDD++KLT
Sbjct: 1307 DKMLADLDMRRDVQEIFRLTPHEKQVMMFSATLSKEIRPICKKFMQDPMEVYVDDDSKLT 1486

Query: 259  LHGLQQYYVKLKDNEKNRKLFDLLDVLEFNQVVIFVKSVQRCIALAQLLVEQNFPAIAIH 318
            LHGLQQ+Y KLKDNEKNRKLF+LLDVLEFNQV+IFVKSV RC+AL+QLL+EQNFPAIAIH
Sbjct: 1487 LHGLQQHYCKLKDNEKNRKLFELLDVLEFNQVIIFVKSVPRCMALSQLLLEQNFPAIAIH 1666

Query: 319  RGMPQEERLSRYQQFKDFQRRILVATNLFGRGMDIERVNIAFNYDMPEDSDTYLHRVARA 378
            R M QEERLSRYQQFKDFQ+RILVATNLFGRGMDIERVNI FNYDMPEDSDTYLHRVARA
Sbjct: 1667 RQMTQEERLSRYQQFKDFQKRILVATNLFGRGMDIERVNIVFNYDMPEDSDTYLHRVARA 1846

Query: 379  GRFGTKGLAITFVSDENDAKILNDVQDRFEVNISELPDEIDISSYIE 425
            GRFGTKGLAITFVSDENDAKILNDVQ+RFEVNI+ELPDEIDISSYIE
Sbjct: 1847 GRFGTKGLAITFVSDENDAKILNDVQERFEVNITELPDEIDISSYIE 1987

 Score = 25.4 bits (54), Expect(2) = 0.0,   Method: Compositional matrix adjust.
 Identities = 9/19 (47%), Positives = 15/19 (78%)
 Frame = +3

Query: 1   MAENDVDNELLDYEDDEVE 19
           MA++  D  +LDYED+E++
Sbjct: 714 MADDTADENILDYEDEEMK 770
>01062
          Length = 2138

 Score =  256 bits (655), Expect = 9e-69,   Method: Compositional matrix adjust.
 Identities = 140/370 (37%), Positives = 218/370 (58%), Gaps = 1/370 (0%)
 Frame = -3

Query: 47   FRDFLLKPELLRAIVDCGFEHPSEVQHECIPQAILGMDVLCQAKSGMGKTAVFVLATLQQ 106
            F +  ++ ELLR I   GFE PS +Q   +   + G DV+ QA+SG GKTA F ++ LQ 
Sbjct: 2073 FDNMGIREELLRGIYAYGFEKPSAIQQRAVKPIVKGRDVIAQAQSGTGKTATFSISVLQC 1894

Query: 107  LEPVTGQVSVLVMCHTRELAFQISKEYERFSKYMPNVKVAVFFGGLSIKKDEEVLKKNCP 166
            L+    +   L++  TRELA QI K       YM NV+     GG +I +D   L     
Sbjct: 1893 LDIQLRETQALILSPTRELATQIQKVMLALGDYM-NVQCHSCIGGTNIGEDIRKLDYG-Q 1720

Query: 167  HIVVGTPGRILALARNKSLNLKHIKHFILDECDKMLEQLDMRRDVQEIFRMTPHEKQVMM 226
            HIV GTPGR+  + + ++L  + IK  ILDE D+ML +   +  + +++R  P   QV++
Sbjct: 1719 HIVSGTPGRVFDMIKRRNLRTRSIKMMILDEADEMLNK-GFKEQIYDVYRYLPPATQVIL 1543

Query: 227  FSATLSKEIRPVCRKFMQDPMEIFVDDETKLTLHGLQQYYVKLKDNE-KNRKLFDLLDVL 285
             SATL  EI  +  KFM DP+ I V  + +LTL G++Q++V ++  E K   L DL D L
Sbjct: 1542 ISATLPHEILEMTNKFMTDPIRILVKRD-ELTLEGIKQFFVAVEREEWKFDTLCDLYDTL 1366

Query: 286  EFNQVVIFVKSVQRCIALAQLLVEQNFPAIAIHRGMPQEERLSRYQQFKDFQRRILVATN 345
               Q VIF  + ++   L + + E NF   ++H  MPQ+ER +  + F+    R+L+ T+
Sbjct: 1365 TITQAVIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKEREAIMKVFRAGDSRVLITTD 1186

Query: 346  LFGRGMDIERVNIAFNYDMPEDSDTYLHRVARAGRFGTKGLAITFVSDENDAKILNDVQD 405
            ++ RG+D+++V++  NYD+P + + Y+HR+ R+GRFG KG+AI FV + +D +IL D++ 
Sbjct: 1185 VWARGIDVQQVSLVINYDLPNNRELYIHRIGRSGRFGRKGVAINFVKN-DDIRILRDIEQ 1009

Query: 406  RFEVNISELP 415
             +   I E+P
Sbjct: 1008 YYSTQIDEMP 979
>00621
          Length = 2263

 Score =  173 bits (438), Expect = 2e-43,   Method: Compositional matrix adjust.
 Identities = 111/417 (26%), Positives = 209/417 (50%), Gaps = 34/417 (8%)
 Frame = +1

Query: 36  KGSYVSIHSSGFRDFLLKPELLRAIVDCGFEHPSEVQHECIPQAILGMDVLCQAKSGMGK 95
           KG  +      +++  L  +++  I   G++ P+ +Q + IP  +   D++  A++G GK
Sbjct: 226 KGGRIPNPIRFWKESDLGADIMEVIDRVGYKEPTPIQMQAIPIGLQNRDIIGVAETGSGK 405

Query: 96  TAVFV---------LATLQQLEPVTGQVSVLVMCHTRELAFQISKEYERFSKYMPNVKVA 146
           TA F+         L  +++LE        +++  TRELA QI +E  +F + +  ++V 
Sbjct: 406 TAAFLIPLLVWIQSLPKIERLEDADQGPYAVILAPTRELAQQIEEETRKFGEGL-GIRVV 582

Query: 147 VFFGGLSIKKDEEVLKKNCPHIVVGTPGRILALARNKSLNLKHIKHFILDECDKMLEQLD 206
              GG+S ++    L++ C  +V+ TPGR++ +  N+ L L    + ++DE D+M+  + 
Sbjct: 583 SVIGGISREEQGFKLQQGC-EVVIATPGRMIDVLENRYLVLNQCTYVVMDEADRMI-NMG 756

Query: 207 MRRDVQEIFRMTP------------------------HE-KQVMMFSATLSKEIRPVCRK 241
              +V++I    P                        H+ +Q +MF+AT+  ++  + R 
Sbjct: 757 FEPEVRKILDYLPVSNQKPDNDDAEDDLKMLQNFKSKHKYRQTVMFTATMPPQVERLART 936

Query: 242 FMQDPMEIFVDDETKLTLHGLQQYYVKLKDNEKNRKLFDLLDVLEFNQVVIFVKSVQRCI 301
           F++ P  +++ +  K  +  ++Q    L ++EK +KL ++L+      ++IFV   +   
Sbjct: 937 FLRRPTVVYIGNVGK-PVERVEQIVYMLTESEKRKKLIEVLNAGVDPPIIIFVNQKKGAD 1113

Query: 302 ALAQLLVEQNFPAIAIHRGMPQEERLSRYQQFKDFQRRILVATNLFGRGMDIERVNIAFN 361
            LA+ L +  F A  +H G  QE+R       K   + I+VAT++ GRG+DI+ V++  N
Sbjct: 1114VLAKSLEKMGFNATTLHGGKGQEQREYALASLKGGAKDIMVATDVAGRGIDIKDVSLVLN 1293

Query: 362 YDMPEDSDTYLHRVARAGRFGTKGLAITFVSDENDAKILNDVQDRFEVNISELPDEI 418
           YDM    + Y HR+ R GR G +G +ITF++ E+     +  Q      +S  P E+
Sbjct: 1294YDMARTIEDYTHRIGRTGRAGKEGTSITFLTKEDSMVFYDLKQLMLSSPVSTCPPEL 1464
>02498
          Length = 1955

 Score = 97.1 bits (240), Expect(2) = 1e-41,   Method: Compositional matrix adjust.
 Identities = 65/202 (32%), Positives = 108/202 (53%), Gaps = 3/202 (1%)
 Frame = +1

Query: 32  KKDVKGSYVSIHSSGFRDFLLKPELLRAIVDCGFEHPSEVQHECIPQAILG--MDVLCQA 89
           +KD      S+ S  F    LKP+LL+ + D GF  PS++Q   +P  +    ++++ Q+
Sbjct: 100 RKDPNSPLYSVKS--FEALNLKPQLLKGVYDMGFNAPSKIQETALPILLADPPVNMIAQS 273

Query: 90  KSGMGKTAVFVLATLQQLEPVTGQVSVLVMCHTRELAFQISKEYERFSKYMPNVKVAVFF 149
           +SG GKTA FVL  L +++        L +  T ELA QI +  E+ SK+M  +++    
Sbjct: 274 QSGTGKTAAFVLTMLSRVDISQTFPQCLCLAPTYELALQIGEVIEKMSKHMTGLEIRYAV 453

Query: 150 GGLSIKKDEEVLKKNCPHIVVGTPGRILALA-RNKSLNLKHIKHFILDECDKMLEQLDMR 208
            G  + +  EVL +    IV+GTPG ++  + R K+L L+ ++ F+LDE D M+     +
Sbjct: 454 RGERVNRG-EVLSE---QIVIGTPGTVMDWSHRFKALPLEKLRVFVLDEADVMISMQGHQ 621

Query: 209 RDVQEIFRMTPHEKQVMMFSAT 230
                I +      Q+++FSAT
Sbjct: 622 DQSTRIQKRLSSGCQMLLFSAT 687

 Score = 90.9 bits (224), Expect(2) = 1e-41,   Method: Compositional matrix adjust.
 Identities = 55/197 (27%), Positives = 97/197 (49%), Gaps = 12/197 (6%)
 Frame = +3

Query: 233 KEIRP----VCRKFM-QDPMEIFVDDETKLTLHGLQQYYVKLKDNE-KNRKLFDLLDVLE 286
           + +RP    VC     QDP+ I +  E + +L  ++QYY+     E K   L ++   + 
Sbjct: 681 RHLRPSGDAVCSAHHPQDPVIISLKREEE-SLDNIKQYYIDCNSQEEKYVALCNIYGSIS 857

Query: 287 FNQVVIFVKSVQRCIALAQLLVEQNFPAIAIHRGMPQEERLSRYQQFKDFQRRILVATNL 346
             Q +IF         LA+ +   +     +   +  E+R +  ++F++ + ++L+ TN+
Sbjct: 858 VGQSMIFCHKRSTAAWLAERMTADHHAVGLLTGELTIEQRAAIIKRFREGKEKVLITTNV 1037

Query: 347 FGRGMDIERVNIAFNYDMP------EDSDTYLHRVARAGRFGTKGLAITFVSDENDAKIL 400
             RG+D+E V +  N+D+P       D +TYLHR+ R GRFG  G+AI  V +     I+
Sbjct: 1038SARGIDVEMVTVVVNFDLPVTQDWRPDCETYLHRIGRTGRFGKNGIAINMVDNSRSMAIM 1217

Query: 401 NDVQDRFEVNISELPDE 417
             ++  F   I +L  E
Sbjct: 1218RSIEKHFGRKIEKLDTE 1268
>07310
          Length = 712

 Score =  142 bits (358), Expect = 3e-34,   Method: Compositional matrix adjust.
 Identities = 81/241 (33%), Positives = 133/241 (55%)
 Frame = +2

Query: 175 RILALARNKSLNLKHIKHFILDECDKMLEQLDMRRDVQEIFRMTPHEKQVMMFSATLSKE 234
           RIL L   + +        +LDE DK+L Q D +  +  I    P ++Q++++SAT    
Sbjct: 2   RILDLMNKRLVKPDTCGILVLDEADKLLSQ-DFKGMLDNIIAHLPPQRQILLYSATFPLS 178

Query: 235 IRPVCRKFMQDPMEIFVDDETKLTLHGLQQYYVKLKDNEKNRKLFDLLDVLEFNQVVIFV 294
           +    +K++++P EI + +E  LTL G+ QYY  +++ +K   L  L   L+ NQ +IF 
Sbjct: 179 VEQFMKKYLKNPYEINLMEE--LTLKGVTQYYAFVQEKQKVHCLNTLFSKLQINQSIIFC 352

Query: 295 KSVQRCIALAQLLVEQNFPAIAIHRGMPQEERLSRYQQFKDFQRRILVATNLFGRGMDIE 354
            S QR   LA+ + E  +    IH  M Q+ R   +  F+    R LV ++LF RG+DI+
Sbjct: 353 NSTQRVELLAKKITELGYSCYYIHAKMNQQHRNRVFHDFRQGLCRNLVCSDLFTRGIDIQ 532

Query: 355 RVNIAFNYDMPEDSDTYLHRVARAGRFGTKGLAITFVSDENDAKILNDVQDRFEVNISEL 414
            VN+  N+D P+ ++TYLHR+ R+GR+G  G+AI  ++ E D   L+ ++      I  +
Sbjct: 533 AVNVVINFDFPKHAETYLHRIGRSGRYGHLGVAINLITFE-DRFSLHKIEQELGTEIKPI 709

Query: 415 P 415
           P
Sbjct: 710 P 712
>02054
          Length = 1110

 Score =  105 bits (263), Expect(2) = 4e-34,   Method: Compositional matrix adjust.
 Identities = 62/180 (34%), Positives = 97/180 (53%)
 Frame = -3

Query: 240 RKFMQDPMEIFVDDETKLTLHGLQQYYVKLKDNEKNRKLFDLLDVLEFNQVVIFVKSVQR 299
           R  ++DP+++ V ++ + T+  LQQ Y+ +    K+  L  +L+ L  N  ++F  +   
Sbjct: 778 RASLRDPVKVEVSNKYQ-TVDTLQQSYLFIPAKYKDAYLVSILNELAGNSFMVFCSTCAN 602

Query: 300 CIALAQLLVEQNFPAIAIHRGMPQEERLSRYQQFKDFQRRILVATNLFGRGMDIERVNIA 359
              +A LL    F AI +H  M Q +RL    +FK   R IL+AT++  RG+DI  V++ 
Sbjct: 601 TQRVALLLRNLGFTAIPLHGQMSQAKRLGSLNKFKSKDRSILIATDVASRGLDIPHVDVV 422

Query: 360 FNYDMPEDSDTYLHRVARAGRFGTKGLAITFVSDENDAKILNDVQDRFEVNISELPDEID 419
            N D+P  S  Y+HRV R  R G  G AITFVS + D ++   ++      +SE P E D
Sbjct: 421 LNLDIPTHSKDYMHRVGRTARAGRSGRAITFVS-QYDVELYQRIEHLIGKKLSEYPTEKD 245

 Score = 57.0 bits (136), Expect(2) = 4e-34,   Method: Compositional matrix adjust.
 Identities = 24/82 (29%), Positives = 50/82 (60%), Gaps = 1/82 (1%)
 Frame = -2

Query: 166  PHIVVGTPGRIL-ALARNKSLNLKHIKHFILDECDKMLEQLDMRRDVQEIFRMTPHEKQV 224
            PHI++ TPGR++  L   K  +L+ +K  ++DE D++L+ ++ + +V +I ++ P E+  
Sbjct: 1001 PHIIIATPGRLVDHLENTKGFSLRALKFLVMDEADRILD-MNFQDEVDKILKVIPRERNT 825

Query: 225  MMFSATLSKEIRPVCRKFMQDP 246
             +FSAT++ ++        + P
Sbjct: 824  YLFSATMTNKVAKTTASITEGP 759
>01517
          Length = 2605

 Score =  125 bits (315), Expect = 2e-29,   Method: Compositional matrix adjust.
 Identities = 80/245 (32%), Positives = 131/245 (53%), Gaps = 6/245 (2%)
 Frame = +2

Query: 185 LNLKHIKHFILDECDKMLE---QLDMRRDVQEIFRMTPHEKQVMMFSATLSKEIRPVCRK 241
           + + H  + +LDE D+ML+   +  +RR V++       ++Q +MFSAT  KEI+ + R 
Sbjct: 26  IGMDHCNYLVLDEADRMLDMGFEPQIRRIVEKDTMPPTGQRQTLMFSATFPKEIQLLARD 205

Query: 242 FMQDPMEIFVDDETKLTLHGLQQYYVKLKDNEKNRKLFDLL---DVLEFNQVVIFVKSVQ 298
           F+ + + + V      T   + Q  V +++ EK   L DLL        +  ++FV++ +
Sbjct: 206 FLDNYIFLAVG-RVGSTSENITQKVVWVEEPEKRSFLLDLLMASGTGPESLTLVFVETKK 382

Query: 299 RCIALAQLLVEQNFPAIAIHRGMPQEERLSRYQQFKDFQRRILVATNLFGRGMDIERVNI 358
              +L Q L+ +N+PA +IH    Q ER    + FK+  R ILVAT +  RG+DI  V  
Sbjct: 383 GADSLEQFLMYENYPATSIHGDRSQREREDALRVFKNGDRPILVATAVAARGLDIPNVRH 562

Query: 359 AFNYDMPEDSDTYLHRVARAGRFGTKGLAITFVSDENDAKILNDVQDRFEVNISELPDEI 418
             N+D+P D + Y+HR+ R GR G  GLA +F +D+N   I  D+ D       E+P  +
Sbjct: 563 VINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNDKN-RNIARDMLDLLTEANQEVPSWL 739

Query: 419 DISSY 423
           +  +Y
Sbjct: 740 ESLAY 754
>00739
          Length = 1313

 Score =  125 bits (313), Expect = 5e-29,   Method: Compositional matrix adjust.
 Identities = 73/255 (28%), Positives = 134/255 (52%), Gaps = 5/255 (1%)
 Frame = +3

Query: 166 PHIVVGTPGRIL-ALARNKSLNLKHIKHFILDECDKMLEQLDMRRDVQEIFRMTPHEKQV 224
           PHIV+ TPGR+   +    + +LK +K  ++DE D++L+  +    ++ I    P  +Q 
Sbjct: 42  PHIVISTPGRLADHIDSCDTFSLKRVKFLVMDEADRLLDD-NFGAQLEPILTRLPSARQT 218

Query: 225 MMFSATLSKEIRPVCRKFMQDPMEIFVDDETKLTLHGLQQYYVKLKDNEKNRKLFDLLDV 284
           ++FSATLS  +  +    +  P  +++    + T+  LQ+ YV +  + K+  +  +LD 
Sbjct: 219 LLFSATLSPTVNALRDSVLNKPF-VWIQQSERATVDELQEDYVLVPASMKDAYMVHILDH 395

Query: 285 L----EFNQVVIFVKSVQRCIALAQLLVEQNFPAIAIHRGMPQEERLSRYQQFKDFQRRI 340
                  + ++IF  + +    L  +L +  F    +H  +PQ  RLS   +FK  Q RI
Sbjct: 396 WLKDHPRSSLIIFTXTCKYAQILGMMLEKLQFSCAVLHSMIPQRFRLSSLSRFKSNQTRI 575

Query: 341 LVATNLFGRGMDIERVNIAFNYDMPEDSDTYLHRVARAGRFGTKGLAITFVSDENDAKIL 400
           L++T++  RG+DI  V++  N+++P     Y+HRV R  R G  G +I+ V+ E D K++
Sbjct: 576 LISTDVASRGLDIPTVDLIINHNIPNRPRDYVHRVGRTARAGRCGQSISLVT-EFDIKLI 752

Query: 401 NDVQDRFEVNISELP 415
             ++      ++E P
Sbjct: 753 KSIESHINCQMTEHP 797
>00162
          Length = 2322

 Score =  121 bits (304), Expect = 4e-28,   Method: Compositional matrix adjust.
 Identities = 86/322 (26%), Positives = 163/322 (50%), Gaps = 10/322 (3%)
 Frame = +3

Query: 77  PQAILGMDVLCQA--KSGMGKTAVFVLATLQQLEPVTGQ---VSVLVMCHTRELAFQISK 131
           P      D++C A  +  + K  +F     +  +  T     +  L++  TRELAFQI +
Sbjct: 12  PPTWPAEDLMCWALPRQALEKLWLFSFLFWRPCQNKTSSAYGMEALIITPTRELAFQIYE 191

Query: 132 EYERFSKYMPNVKVAVFFGGLSIKKDEEVLKKNCPHIVVGTPGRILA-LARNKSLNLKHI 190
              +   +  +    +  GG  + ++  ++ K   +IV+ T GR+L  L   ++ ++  +
Sbjct: 192 VLNKIRTFH-DFSANLVIGGKFMWRETHLMGKT--NIVICTVGRLLHHLESTQAFDVSEL 362

Query: 191 KHFILDECDKMLEQLDMRRDVQEIFRMTPHEKQVMMFSATLSKEIRPVCRKFMQDPMEIF 250
           K  +LDE D++++     +D+  I    P  +Q ++FSAT +  ++ + R  ++DP  + 
Sbjct: 363 KVLVLDEADRIMDS-KFAQDMDSIMSHLP-PRQTLLFSATQTMSVKTLARLSLKDPSYVS 536

Query: 251 VDDETK-LTLHGLQQYYVKLKDNEKNRKLFDLLDVLEFNQVVIFVKSVQRCIALAQLLVE 309
           VD   + +T  GL+Q Y+  + +EK   L+  L     N++++F+++ ++       +++
Sbjct: 537 VDRHAEYVTPTGLEQSYIVCELHEKLSLLYSFLKNHPNNKIMVFLQTCKQA-RYVHTVIK 713

Query: 310 QNFPAIAI---HRGMPQEERLSRYQQFKDFQRRILVATNLFGRGMDIERVNIAFNYDMPE 366
           +  P +++   H G+PQ  RL  Y++F   Q  IL+ T+L  RG+D   VN     D P 
Sbjct: 714 RERPGMSVLVLHGGIPQLRRLDIYREFCRKQHVILITTDLACRGLDFPAVNWVIQLDCPV 893

Query: 367 DSDTYLHRVARAGRFGTKGLAI 388
           D +TY+HR  R  RF   G A+
Sbjct: 894 DVNTYIHRAGRTARFECNGQAL 959
>19525
          Length = 585

 Score =  101 bits (251), Expect = 7e-22,   Method: Compositional matrix adjust.
 Identities = 56/161 (34%), Positives = 99/161 (61%), Gaps = 1/161 (0%)
 Frame = +2

Query: 116 VLVMCHTRELAFQISKEYERFSKYMPNVKVAVFFGGLSIKKDEEVLKKNCPHIVVGTPGR 175
           VLV+  TRELA Q+ +  ++ S+Y   + + +  GGL IK  E  L+  CP IVV TPGR
Sbjct: 20  VLVLVPTRELAVQVYQVGQQISQY-TKISICLAAGGLDIKGQEAALRL-CPDIVVATPGR 193

Query: 176 ILALARNK-SLNLKHIKHFILDECDKMLEQLDMRRDVQEIFRMTPHEKQVMMFSATLSKE 234
           ++    N  +  + H++  +LDE D+ML++      + EI RM   ++Q M+FSAT+S  
Sbjct: 194 LIDHLHNAPNFTIAHVEILVLDEADRMLDEY-FAAQMTEIIRMCNFQRQTMLFSATMSDA 370

Query: 235 IRPVCRKFMQDPMEIFVDDETKLTLHGLQQYYVKLKDNEKN 275
           ++ +    +++ +++FV+  T + L GLQQ +V++++N++ 
Sbjct: 371 VQDLASVSLKEAVKVFVNQNTDIAL-GLQQEFVRIRENKEG 490
>08036
          Length = 1226

 Score = 67.8 bits (164), Expect(2) = 6e-19,   Method: Compositional matrix adjust.
 Identities = 49/181 (27%), Positives = 92/181 (50%), Gaps = 4/181 (2%)
 Frame = +1

Query: 169 VVGTPGRILALARNKSLNLKHIKHFILDECDKMLE---QLDMRRDVQEIFRMTPHEKQVM 225
           VVGTP RILA  R   L L  ++  ++DE D +     + DM++ ++E+    P   Q  
Sbjct: 1   VVGTPSRILAHLRAGHLELHTVQMLVVDEADLVFSFGHEADMKKLMEEL----PRIYQAF 168

Query: 226 MFSATLSKEIRPVCRKFMQDPMEIFVDDETKLTLHGLQQYYVKLKDNEKNRKLFDLLDV- 284
           + SATLS++++ + +  + +P+ + + +        L QY+VK + ++K   +  +L + 
Sbjct: 169 LMSATLSEDVKALKKMVLHNPVILKLKESQLPESTQLTQYHVKCEVDDKFTLMVAVLKLG 348

Query: 285 LEFNQVVIFVKSVQRCIALAQLLVEQNFPAIAIHRGMPQEERLSRYQQFKDFQRRILVAT 344
           L   + ++FV SV  C  L   L     PA  ++  +P + R     QF +    I++A+
Sbjct: 349 LVRGKSILFVNSVDSCYKLKLFLEPFGIPACVLNSELPVKSRCHIVSQFNEGLYDIIIAS 528

Query: 345 N 345
           +
Sbjct: 529 D 531

 Score = 44.3 bits (103), Expect(2) = 6e-19,   Method: Compositional matrix adjust.
 Identities = 19/50 (38%), Positives = 30/50 (60%), Gaps = 1/50 (2%)
 Frame = +3

Query: 348 GRGMDIERVNIAFNYDMPEDSDTYLHRVARAGRFGTKGLAITFVS-DEND 396
            RG+D + V+   N++ P+  D Y+HRV R  R   +G A++ +S  END
Sbjct: 612 ARGIDFQNVSNVINFEFPKTVDAYIHRVGRTARGDKQGCALSLISRHEND 761
>09327
          Length = 1087

 Score = 90.5 bits (223), Expect = 1e-18,   Method: Compositional matrix adjust.
 Identities = 61/240 (25%), Positives = 118/240 (49%), Gaps = 3/240 (1%)
 Frame = +2

Query: 115 SVLVMCHTRELAFQISKEYERFSKYMPNVKVAVFFGGLSIKKDEEVLKKNCPHIVVGTPG 174
            + ++  TRELA Q+ +    F  +   V+    +GG         L +    I + TPG
Sbjct: 11  CIWLLVPTRELAQQVQEVAVEFG-HSSRVRSVCVYGGAQRGPQLRELDRG-AEICIATPG 184

Query: 175 RILALARNKSLNLKHIKHFILDECDKMLEQLDMRRDVQEIFRMTPHEKQVMMFSATLSKE 234
           R++    +   NL+   + +LDE D+ML+ +     +++I      ++Q +M+SAT  KE
Sbjct: 185 RLIDFLESNRTNLRRCTYLVLDEADRMLD-MGFEPQIRKIVEQIRPDRQTLMWSATWPKE 361

Query: 235 IRPVCRKFMQDPMEIFVDDETKLTLHGLQQYYVKLKDNEKNRKLFDLLDVL---EFNQVV 291
           +R +   F+ +  +I +        H + Q      D+EK  KL  LL+ +   + N+ +
Sbjct: 362 VRKLAEDFIMEYTQINIGALQLTANHNILQIIDVCMDHEKEEKLVKLLNEIMQEKENRTL 541

Query: 292 IFVKSVQRCIALAQLLVEQNFPAIAIHRGMPQEERLSRYQQFKDFQRRILVATNLFGRGM 351
           IFV++ ++C  + + +    +P + IH    Q+ER      F++ +  +L+AT++  RG+
Sbjct: 542 IFVETKRKCDDIHRRMKRDGWPVLCIHGDKSQQERDWVLNDFRNGRCPVLLATDVASRGL 721
>33543
          Length = 471

 Score = 89.7 bits (221), Expect = 2e-18,   Method: Compositional matrix adjust.
 Identities = 37/56 (66%), Positives = 50/56 (89%)
 Frame = +3

Query: 370 TYLHRVARAGRFGTKGLAITFVSDENDAKILNDVQDRFEVNISELPDEIDISSYIE 425
           TYLHRV RAGRFGT+GLAITFVS+E +A +LN VQ+RFEV++++LP++I +S+Y E
Sbjct: 3   TYLHRVGRAGRFGTRGLAITFVSNETEADVLNSVQERFEVSVTDLPEQISVSTYTE 170
>04883
          Length = 1155

 Score = 87.4 bits (215), Expect = 9e-18,   Method: Compositional matrix adjust.
 Identities = 60/225 (26%), Positives = 110/225 (48%), Gaps = 6/225 (2%)
 Frame = +3

Query: 65  FEHPSEVQHECIPQAILGMDVLCQAKSGMGKTAVFVLATLQQ------LEPVTGQVSVLV 118
           +  P+ +Q +  P A+ G D++  A++G GKT  F+L  +        LE   G + VL 
Sbjct: 420 WTAPTPIQSQSWPVAMAGKDLVGIAQTGSGKTLAFMLPAIVHINHQAYLERGDGPI-VLA 596

Query: 119 MCHTRELAFQISKEYERFSKYMPNVKVAVFFGGLSIKKDEEVLKKNCPHIVVGTPGRILA 178
           +  TRELA Q+ +  + F  +   V+    +GG         L++    I + TPGR++ 
Sbjct: 597 LVPTRELAQQVQEVAQEFG-HASRVRSVCVYGGAPRGPQLRDLERGA-EICIATPGRLID 770

Query: 179 LARNKSLNLKHIKHFILDECDKMLEQLDMRRDVQEIFRMTPHEKQVMMFSATLSKEIRPV 238
              +   NL+   + +LDE D+ML+ +     +++I      ++Q +M+SAT  KE+R +
Sbjct: 771 FLESNRTNLRRCTYLVLDEADRMLD-MGFEPQIRKIIEQIRPDRQTLMWSATWPKEVRKL 947

Query: 239 CRKFMQDPMEIFVDDETKLTLHGLQQYYVKLKDNEKNRKLFDLLD 283
              F+ + +++ +        H + Q      ++EK  KL  LL+
Sbjct: 948 AEDFIDEYVQVNIGALELTANHNILQIIDVCMEHEKEDKLVKLLN 1082
>31899
          Length = 453

 Score = 82.8 bits (203), Expect = 2e-16,   Method: Compositional matrix adjust.
 Identities = 41/113 (36%), Positives = 60/113 (53%)
 Frame = -1

Query: 47  FRDFLLKPELLRAIVDCGFEHPSEVQHECIPQAILGMDVLCQAKSGMGKTAVFVLATLQQ 106
           F   LL   +L  + + GFE PS +Q + IP    G+D++ QAKSG GKT VF +  L+ 
Sbjct: 339 FASLLLSKPVLNGLKNAGFERPSPIQLKAIPLGRCGLDLIVQAKSGTGKTCVFSVVALEG 160

Query: 107 LEPVTGQVSVLVMCHTRELAFQISKEYERFSKYMPNVKVAVFFGGLSIKKDEE 159
           +E       VLV+  TRE+A QI +        M  ++   F GGL + +D +
Sbjct: 159 IETTARSTQVLVLAPTREIALQIWEVINSIGSAMSGLQCHTFIGGLPVHEDRK 1
>14337
          Length = 693

 Score = 82.8 bits (203), Expect = 3e-16,   Method: Compositional matrix adjust.
 Identities = 45/127 (35%), Positives = 69/127 (54%)
 Frame = +2

Query: 290 VVIFVKSVQRCIALAQLLVEQNFPAIAIHRGMPQEERLSRYQQFKDFQRRILVATNLFGR 349
           V++FV+S QR   L    +       AIH   PQ ER +  + F + +  +LV T L GR
Sbjct: 65  VLVFVQSKQRAKELYSEFMFDKHKVDAIHADKPQAERDATVRAFTEGRVWVLVCTELMGR 244

Query: 350 GMDIERVNIAFNYDMPEDSDTYLHRVARAGRFGTKGLAITFVSDENDAKILNDVQDRFEV 409
           G+D + +N+  NYD P ++ +Y+HR+ R GR G  G AITF + E D   L  + +  + 
Sbjct: 245 GIDFKGINLVINYDFPTNAVSYIHRIGRTGRAGVPGRAITFFT-EQDVTHLRSIANIIKE 421

Query: 410 NISELPD 416
              E+P+
Sbjct: 422 AGCEVPE 442
>34295
          Length = 694

 Score = 81.3 bits (199), Expect = 7e-16,   Method: Compositional matrix adjust.
 Identities = 40/126 (31%), Positives = 66/126 (52%)
 Frame = -1

Query: 290 VVIFVKSVQRCIALAQLLVEQNFPAIAIHRGMPQEERLSRYQQFKDFQRRILVATNLFGR 349
           V+IF  + + C  L+  L       + +H  M Q+ER+S   +FK    R L+AT++  R
Sbjct: 535 VMIFTNTKKYCQLLSMTLTNMEIENVCLHGFMRQKERVSALSRFKSNHIRTLIATDVAAR 356

Query: 350 GMDIERVNIAFNYDMPEDSDTYLHRVARAGRFGTKGLAITFVSDENDAKILNDVQDRFEV 409
           G+DI  V +  N+ +P     Y+HRV R  R G KG+AI+      D ++L  +++    
Sbjct: 355 GLDIPSVQLVINHMLPRTPKEYIHRVGRTARAGRKGVAISIFRFPRDLELLGAIEEEINT 176

Query: 410 NISELP 415
            ++E P
Sbjct: 175 KLTEHP 158
>03336
          Length = 1352

 Score = 77.8 bits (190), Expect = 7e-15,   Method: Compositional matrix adjust.
 Identities = 38/40 (95%), Positives = 40/40 (100%)
 Frame = -1

Query: 386 LAITFVSDENDAKILNDVQDRFEVNISELPDEIDISSYIE 425
           LAITFVSDENDAKILNDVQ+RFEVNI+ELPDEIDISSYIE
Sbjct: 443 LAITFVSDENDAKILNDVQERFEVNITELPDEIDISSYIE 324
>00617
          Length = 1505

 Score = 75.1 bits (183), Expect = 5e-14,   Method: Compositional matrix adjust.
 Identities = 37/110 (33%), Positives = 62/110 (56%)
 Frame = -3

Query: 306  LLVEQNFPAIAIHRGMPQEERLSRYQQFKDFQRRILVATNLFGRGMDIERVNIAFNYDMP 365
            +L +  F    +H  +PQ  RLS   +FK  Q RIL++T++  RG+DI  V++  N+++P
Sbjct: 1500 MLEKLQFSCAVLHSMIPQRFRLSSLSRFKSNQTRILISTDVASRGLDIPTVDLIINHNIP 1321

Query: 366  EDSDTYLHRVARAGRFGTKGLAITFVSDENDAKILNDVQDRFEVNISELP 415
                 Y+HRV R  R G  G +I+ V+ E D K++  ++      ++E P
Sbjct: 1320 NRPRDYVHRVGRTARAGRCGQSISLVT-EFDIKLIKSIESHINCQMTEHP 1174
>19640
          Length = 456

 Score = 72.8 bits (177), Expect = 2e-13,   Method: Compositional matrix adjust.
 Identities = 30/88 (34%), Positives = 52/88 (59%)
 Frame = -1

Query: 292 IFVKSVQRCIALAQLLVEQNFPAIAIHRGMPQEERLSRYQQFKDFQRRILVATNLFGRGM 351
           IF  + ++   L Q +   NF   A+H  M Q +R    +QF+    R+L+ T+L  RG+
Sbjct: 456 IFCNTRRKVDQLTQEMSSHNFTVSAMHGDMEQRDREVIMKQFRSGSSRVLITTDLLARGI 277

Query: 352 DIERVNIAFNYDMPEDSDTYLHRVARAG 379
           D+++V++  NYD+P + + Y+HR+ R G
Sbjct: 276 DVQQVSLVINYDLPSNRENYIHRIGRGG 193
>11624
          Length = 2257

 Score = 69.3 bits (168), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 47/146 (32%), Positives = 68/146 (46%), Gaps = 1/146 (0%)
 Frame = -1

Query: 247  MEIFVDDETKLTLHGLQQYYVKLKDNEKNRKLFDLLDVLEFNQVVIFVKSVQRCIALAQL 306
            ME FV   T  T  GL +Y V+   +EK   +   L  L+F  V+ F  SV+    L  L
Sbjct: 1018 MENFVGKYT--TPEGLTEYIVESDSSEKPLLVLHFLHNLKFRSVLCFTNSVETTHRLCLL 845

Query: 307  L-VEQNFPAIAIHRGMPQEERLSRYQQFKDFQRRILVATNLFGRGMDIERVNIAFNYDMP 365
            + +            +P E R    +QF   +  +LV ++   RGMD++ V    +YD P
Sbjct: 844  VKLYGGLSVKEFSSRLPGERRKKILKQFSKGKIDLLVCSDAMARGMDVDNVKYVISYDNP 665

Query: 366  EDSDTYLHRVARAGRFGTKGLAITFV 391
                TY+HRV R  R G  G AI+ +
Sbjct: 664  PYIKTYIHRVGRTARAGRAGTAISLL 587

 Score = 52.4 bits (124), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 53/228 (23%), Positives = 96/228 (42%), Gaps = 35/228 (15%)
 Frame = -3

Query: 51   LLKPELLRAIVDCGFEHPSEVQHECIPQ--------------AILGMDVLCQAKSGMGKT 96
            +L  +L   + D G +    VQ E IP+               +   D+   A +G GKT
Sbjct: 1952 VLDDQLRGKLHDSGIDRLFPVQREFIPELWKDVRYSLTAGRYGLRPRDICVSAPTGSGKT 1773

Query: 97   AVFVLATLQQL-EPVTGQVSVLVMCHTRELAFQISKEYERFSKYMPN--VKVAVFFGGLS 153
              + L  +Q L + +   V  +++   R+LA Q+   Y+ F  Y  +  +KV +  G   
Sbjct: 1772 LAYTLPIIQCLKQRMVPHVRAVIVLPVRDLAEQV---YQVFCHYCADTPLKVGIVVGKTV 1602

Query: 154  IKKDEEVLKK--------NCPHIVVGTPGRIL-ALARNKSLNLKHIKHFILDECDKMLEQ 204
               +++ L K        +   I+V TPGR++  +      +L H++  ++DE D+M+E 
Sbjct: 1601 FNVEQDTLVKKRYGGVYHSVIDILVATPGRLVDHINSTPGFDLSHLRFLVIDEADRMMED 1422

Query: 205  LDMRR-DVQEIFRMTPHEKQVMMFSA--------TLSKEIRPVCRKFM 243
            + +    V E    TP  +   + S         T+    R  CR+ +
Sbjct: 1421 IKLDWLSVVETAAFTPTHRLTSL*SGHNQALSLLTVPSVYRCHCRRLL 1278
>19151
          Length = 625

 Score = 69.3 bits (168), Expect = 3e-12,   Method: Compositional matrix adjust.
 Identities = 31/82 (37%), Positives = 48/82 (58%), Gaps = 6/82 (7%)
 Frame = -3

Query: 339 RILVATNLFGRGMDIERVNIAFNYDMP------EDSDTYLHRVARAGRFGTKGLAITFVS 392
           ++L+ TN+  RG+DIE+V I  N+D+P       D +TYLHR+ R GRFG  G+AI  + 
Sbjct: 623 KVLITTNVLSRGIDIEQVTIVVNFDLPIDLRGNADCETYLHRIGRTGRFGKSGIAINLID 444

Query: 393 DENDAKILNDVQDRFEVNISEL 414
            E    +   ++  F+ +I  L
Sbjct: 443 GEKSMNVCRAIEKHFQKDIVYL 378
>10649
          Length = 472

 Score = 65.5 bits (158), Expect = 4e-11,   Method: Compositional matrix adjust.
 Identities = 30/75 (40%), Positives = 41/75 (54%)
 Frame = +1

Query: 314 AIAIHRGMPQEERLSRYQQFKDFQRRILVATNLFGRGMDIERVNIAFNYDMPEDSDTYLH 373
            + +H G+PQ  RL  Y++F   Q  IL+ T+L  RG+D   VN     D P D +TY+H
Sbjct: 73  VLVLHGGIPQLRRLDIYREFCRKQHVILITTDLACRGLDFPAVNWVIQLDCPVDVNTYIH 252

Query: 374 RVARAGRFGTKGLAI 388
           R  R  RF   G A+
Sbjct: 253 RAGRTARFECNGQAL 297
>12995
          Length = 1072

 Score = 62.8 bits (151), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 42/158 (26%), Positives = 79/158 (50%), Gaps = 2/158 (1%)
 Frame = +3

Query: 246 PMEIFVDDETKLTLHGLQQYYVKLKDNEKNRKLFDLL-DVLEFNQV-VIFVKSVQRCIAL 303
           P  + +D ++KL+   LQ  ++  + ++K   L  LL DV+  N + V+FV +      L
Sbjct: 3   PTLVRLDVDSKLSAQ-LQMSFLSCRADDKEAMLLYLLRDVISENDLTVVFVATKHHVEYL 179

Query: 304 AQLLVEQNFPAIAIHRGMPQEERLSRYQQFKDFQRRILVATNLFGRGMDIERVNIAFNYD 363
             LL +       I+  + Q  R     +F   Q ++++ T+L  RG+DI +++   N+ 
Sbjct: 180 NTLLTKCGIACTYIYSSLDQTARKIHVAKFTHKQVKVMLVTDLAARGIDIPQLDNVVNFH 359

Query: 364 MPEDSDTYLHRVARAGRFGTKGLAITFVSDENDAKILN 401
            P  +  ++HRV R  R G  G A + V+ +  A +++
Sbjct: 360 FPAKAKLFVHRVGRVARAGRSGTAYSLVAMDEVAHLVD 473
>11160
          Length = 646

 Score = 57.8 bits (138), Expect = 9e-09,   Method: Compositional matrix adjust.
 Identities = 51/196 (26%), Positives = 93/196 (47%), Gaps = 18/196 (9%)
 Frame = -1

Query: 150 GGLSIKKDEEVLKKNCPHIVVGTPGRILAL------ARNKSLNLKHIKHFILDECDKMLE 203
           GG+S   D     K+   I++ TPGR+  L        N + ++K ++  +LDE D++L+
Sbjct: 646 GGVSCSHDISKFMKSGGSILIATPGRLDDLFSRKESGFNLAASVKALEVLVLDEADRLLD 467

Query: 204 QLDMRRDVQEIFRMTPHEKQVMMFSATLSKEIRPVCRKFMQDPMEIFVDDETKL------ 257
            +     +  I    P  ++  +FSAT + E+  + R  +++P+ + V  E KL      
Sbjct: 466 -MGFEASINTILGHLPKLRRTGLFSATQTDEVENLIRAGLRNPLRVTV-KEKKLAGEADQ 293

Query: 258 -TLHGLQQYYVKLKDNEKNRKLFDLLDVLEFNQVVIFVKSVQRCI-----ALAQLLVEQN 311
            T   L  YY+ ++  EK  +L   L     +++++F  S   C+      L QLL  ++
Sbjct: 292 RTPSTLSNYYMIVEAEEKFSQLVKFLKTHHRDKLLLFF-STCACVDYFSMCLTQLL--KH 122

Query: 312 FPAIAIHRGMPQEERL 327
              ++IH  M Q+  L
Sbjct: 121 MQVLSIHSKMKQKRNL 74
>33025
          Length = 558

 Score = 56.2 bits (134), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 39/127 (30%), Positives = 73/127 (57%), Gaps = 4/127 (3%)
 Frame = +3

Query: 129 ISKEYERFSKYMPNVKVAVFFGGLSIKKDEEVLKKNCPHIVVGTPGRILALARNKSLNLK 188
           I  E  +FS+   +V  +V +G    +  +  + K   ++VVGTPGR+L    +++++L 
Sbjct: 3   IYGEAYKFSR-GTDVHPSVVYGATDRRYQKSRIMKG-ANLVVGTPGRLLDFIGDQTISLG 176

Query: 189 HIKHFILDECDKMLE---QLDMRRDVQEIFRMTPH-EKQVMMFSATLSKEIRPVCRKFMQ 244
             ++ ILDE D+ML+   + ++R+ V +   M P  ++Q +MFSAT  ++I+ +   F+ 
Sbjct: 177 KCQYLILDEADRMLDMGFEPEIRKLV-DTHGMPPKTQRQTLMFSATFKEDIQRLAGDFLN 353

Query: 245 DPMEIFV 251
           D + I V
Sbjct: 354 DYLFITV 374
>39583
          Length = 234

 Score = 52.0 bits (123), Expect = 4e-07,   Method: Composition-based stats.
 Identities = 24/58 (41%), Positives = 35/58 (60%)
 Frame = -3

Query: 325 ERLSRYQQFKDFQRRILVATNLFGRGMDIERVNIAFNYDMPEDSDTYLHRVARAGRFG 382
           +RL   ++FK+ +  +L+AT+L  RG+DIE V    N+ MP     Y+HRV R  R G
Sbjct: 175 QRLEALKRFKEGEIDVLLATDLASRGLDIEGVKTVINFTMPSTLKHYVHRVGRTARAG 2
>03381
          Length = 1206

 Score = 48.9 bits (115), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 28/83 (33%), Positives = 46/83 (55%), Gaps = 5/83 (6%)
 Frame = +3

Query: 351 MDIERVNIAFNYDMPEDSDTYLHRVARAGRFGTKGLAITFVSDEND--AKILNDVQDRFE 408
           +DI  +    NYD+  D DT+ HRV R GR G KG A T ++D++   A +L  V++   
Sbjct: 3   LDIPHIRTVVNYDVARDIDTHTHRVGRTGRAGEKGSAYTLITDKDKEFAPLL--VRNLEG 176

Query: 409 VNISELPDEIDISS---YIEQTR 428
            N +  P  +D+++   +  +TR
Sbjct: 177 ANQTPPPALLDLANQCPWFNKTR 245
>31220
          Length = 818

 Score = 44.7 bits (104), Expect = 7e-05,   Method: Compositional matrix adjust.
 Identities = 18/45 (40%), Positives = 25/45 (55%)
 Frame = +2

Query: 348 GRGMDIERVNIAFNYDMPEDSDTYLHRVARAGRFGTKGLAITFVS 392
            RG+D + VN   N+D P D  +Y+HR  R  R    G  ++FVS
Sbjct: 164 SRGIDFQGVNNVINFDFPLDVTSYIHRAGRTARGNNTGSVLSFVS 298
>19172
          Length = 484

 Score = 42.0 bits (97), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 29/114 (25%), Positives = 57/114 (50%), Gaps = 3/114 (2%)
 Frame = -1

Query: 241 KFMQDPMEIFVDDETKLTLHGLQQYYVKLKDNEKNRKLFDLLDVLEF---NQVVIFVKSV 297
           +F+ + +++ +   +    H + Q      ++EK  KL  LL  +      + +IFV++ 
Sbjct: 484 EFLNNYIQVNIGSLSLSANHNILQIVDVCDESEKIAKLIQLLTQISGENETKTIIFVETK 305

Query: 298 QRCIALAQLLVEQNFPAIAIHRGMPQEERLSRYQQFKDFQRRILVATNLFGRGM 351
           +R   + + +  Q + A AIH    Q+ER      F++ +  ILVAT++  RG+
Sbjct: 304 KRVDEITRNISRQGWRACAIHGDKSQQERDFVLSSFRNGRHSILVATDVAARGL 143
>06438
          Length = 989

 Score = 41.6 bits (96), Expect = 6e-04,   Method: Compositional matrix adjust.
 Identities = 18/47 (38%), Positives = 23/47 (48%)
 Frame = +1

Query: 342 VATNLFGRGMDIERVNIAFNYDMPEDSDTYLHRVARAGRFGTKGLAI 388
           +   L  RG+D   VN     D P D +TY+HR  R  RF   G A+
Sbjct: 25  LTVTLACRGLDFPAVNWVIQLDCPVDVNTYIHRAGRTARFECNGQAL 165
>33083
          Length = 1931

 Score = 41.2 bits (95), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 19/47 (40%), Positives = 28/47 (59%), Gaps = 1/47 (2%)
 Frame = +1

Query: 349 RGMDIERVNIAFNYDMPEDSDTYLHRVARAGRF-GTKGLAITFVSDE 394
           RG+DI +V+    YD P++S  Y+HRV R  R  G+ G A+  +  E
Sbjct: 1   RGLDIPQVDWIVQYDPPDESKEYIHRVGRTARGEGSSGKALLLLQPE 141
>12121
          Length = 465

 Score = 35.4 bits (80), Expect = 0.047,   Method: Compositional matrix adjust.
 Identities = 13/36 (36%), Positives = 22/36 (61%)
 Frame = -3

Query: 168 IVVGTPGRILALARNKSLNLKHIKHFILDECDKMLE 203
           I + TPGR++    +   NL+   + +LDE D+ML+
Sbjct: 463 ICIATPGRLIDFLESNRTNLRRCTYLVLDEADRMLD 356
>11423
          Length = 1434

 Score = 34.7 bits (78), Expect = 0.070,   Method: Compositional matrix adjust.
 Identities = 17/48 (35%), Positives = 23/48 (47%)
 Frame = -2

Query: 347  FGRGMDIERVNIAFNYDMPEDSDTYLHRVARAGRFGTKGLAITFVSDE 394
            +GRG          +YD P    TY+HRV R  R G  G AI+ +  +
Sbjct: 1415 YGRGQR----KYVISYDNPPYIKTYIHRVGRTARAGRAGTAISLLEKK 1284
>02305
          Length = 2401

 Score = 29.3 bits (64), Expect = 3.3,   Method: Compositional matrix adjust.
 Identities = 13/23 (56%), Positives = 15/23 (65%)
 Frame = +3

Query: 45  SGFRDFLLKPELLRAIVDCGFEH 67
           SG  D LL P L   +VDCGF+H
Sbjct: 801 SGHSDSLLSPNL--CLVDCGFQH 863
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|9790083|ref|NP_062659.1| RuvB-like protein 1 [Mus
musculus]
         (456 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

01279                                                                 384   0.0  
14389                                                                 315   2e-86
23413                                                                 178   5e-45
39786                                                                  45   5e-12
20270                                                                  40   0.002
23766                                                                  39   0.003
07243                                                                  37   0.021
19129                                                                  37   0.023
01642                                                                  36   0.025
17843                                                                  36   0.025
03022                                                                  35   0.074
19561                                                                  34   0.14 
26408                                                                  33   0.23 
27434                                                                  33   0.26 
09184                                                                  29   4.3  
15498                                                                  29   4.6  
01586                                                                  29   4.8  
30094                                                                  28   8.7  
>01279
          Length = 2183

 Score =  384 bits (986), Expect(3) = 0.0,   Method: Compositional matrix adjust.
 Identities = 175/227 (77%), Positives = 209/227 (92%)
 Frame = -2

Query: 230  KKKEIIQDVTLHDLDVANARPQGGQDILSMMGQLMKPKKTEITDKLRGEINKVVNKYIDQ 289
            +KKE+IQDVTLHDLDVANARPQGGQDI+SMMGQLMKPKKTEITDKLR EINKVVNKYIDQ
Sbjct: 1417 QKKEVIQDVTLHDLDVANARPQGGQDIMSMMGQLMKPKKTEITDKLRKEINKVVNKYIDQ 1238

Query: 290  GVAELVPGVLFVDEVHMLDIECFTYLHRALESSIAPIVIFASNRGNCVIRGTEDITSPHG 349
            G+AELVPGVLF+DEVHMLDIECFTYLHRALES+IAPIVIFA+NRG C I+GTEDI SPHG
Sbjct: 1237 GIAELVPGVLFIDEVHMLDIECFTYLHRALESTIAPIVIFATNRGKCTIKGTEDIISPHG 1058

Query: 350  IPLDLLDRVMIIRTMLYTPQEMKQIIKIRAQTEGINISEEALNHLGEIGTKTTLRYSVQL 409
            +P+DLLDRVMI+RT+ Y+ +EM QI++IR+QTE I + EE++ HLG IG +TTLRY+VQL
Sbjct: 1057 MPMDLLDRVMIVRTLPYSQEEMTQILQIRSQTENIQVEEESIQHLGNIGVRTTLRYAVQL 878

Query: 410  LTPANLLAKINGKDSIEKEHVEEISELFYDAKSSAKILADQQDKYMK 456
            LTP ++LA+INGKD++ KE +EEI +LF+DAK+SAKIL +Q+DKY+K
Sbjct: 877  LTPGSILARINGKDNVGKEEIEEIDKLFFDAKASAKILQEQEDKYLK 737

 Score =  381 bits (979), Expect(3) = 0.0,   Method: Compositional matrix adjust.
 Identities = 185/211 (87%), Positives = 201/211 (95%)
 Frame = -3

Query: 22   KGLGLDESGLAKQAASGLVGQENAREACGVIVELIKSKKMAGRAVLLAGPPGTGKTALAL 81
            KG+   E+G A Q+++GLVGQE AREA GV+VELIK+KKMAGRAVLLAGPPGTGKTA+AL
Sbjct: 2040 KGIRTCENGYAIQSSAGLVGQEGAREAAGVVVELIKTKKMAGRAVLLAGPPGTGKTAIAL 1861

Query: 82   AIAQELGSKVPFCPMVGSEVYSTEIKKTEVLMENFRRAIGLRIKETKEVYEGEVTELTPC 141
            AIAQELG+KVPFCPMVGSEVYS+EIKKTEVLMENFRRAIGLRIKETKEVYEGEVTELTP 
Sbjct: 1860 AIAQELGNKVPFCPMVGSEVYSSEIKKTEVLMENFRRAIGLRIKETKEVYEGEVTELTPV 1681

Query: 142  ETENPMGGYGKTISHVIIGLKTAKGTKQLKLDPSIFESLQKERVEAGDVIYIEANSGAVK 201
            ETENPMGGYGKT+SHV+IGLKTAKGTKQLKLDPSI+ESLQKE+VE GDVIYIEANSGAVK
Sbjct: 1680 ETENPMGGYGKTVSHVVIGLKTAKGTKQLKLDPSIYESLQKEKVEVGDVIYIEANSGAVK 1501

Query: 202  RQGRCDTYATEFDLEAEEYVPLPKGDVHKKK 232
            RQGR D+YATEFDLEAEEYVPLPKGDVHK+K
Sbjct: 1500 RQGRSDSYATEFDLEAEEYVPLPKGDVHKRK 1408

 Score = 23.5 bits (49), Expect(3) = 0.0,   Method: Compositional matrix adjust.
 Identities = 11/11 (100%), Positives = 11/11 (100%)
 Frame = -2

Query: 1    MKIEEVKSTTK 11
            MKIEEVKSTTK
Sbjct: 2101 MKIEEVKSTTK 2069

 Score = 36.2 bits (82), Expect = 0.026,   Method: Compositional matrix adjust.
 Identities = 16/21 (76%), Positives = 18/21 (85%)
 Frame = -1

Query: 11   KTQRIASHSHVKGLGLDESGL 31
            K QRIASHSHVKGLGL + G+
Sbjct: 2072 KAQRIASHSHVKGLGLAKMGM 2010
>14389
          Length = 790

 Score =  315 bits (808), Expect = 2e-86,   Method: Compositional matrix adjust.
 Identities = 150/167 (89%), Positives = 162/167 (97%)
 Frame = +3

Query: 74  TGKTALALAIAQELGSKVPFCPMVGSEVYSTEIKKTEVLMENFRRAIGLRIKETKEVYEG 133
           TGKTA+ALAIAQELG+KVPFCPMVGSEV+S EIKKTEVLMENFRR+IGLRI+ETKEVYEG
Sbjct: 3   TGKTAIALAIAQELGNKVPFCPMVGSEVFSNEIKKTEVLMENFRRSIGLRIRETKEVYEG 182

Query: 134 EVTELTPCETENPMGGYGKTISHVIIGLKTAKGTKQLKLDPSIFESLQKERVEAGDVIYI 193
           EVTELTP ETENPMGGYGKTIS+V+IGLKTAKGTKQLKLDPSIF++LQKE+VE GDVIYI
Sbjct: 183 EVTELTPVETENPMGGYGKTISNVVIGLKTAKGTKQLKLDPSIFDALQKEKVEVGDVIYI 362

Query: 194 EANSGAVKRQGRCDTYATEFDLEAEEYVPLPKGDVHKKKEIIQDVTL 240
           EANSGAVKRQGR DT+ATEFDLE EEYVPLPKGDVHKKKE+IQDVTL
Sbjct: 363 EANSGAVKRQGRSDTFATEFDLETEEYVPLPKGDVHKKKEVIQDVTL 503

 Score =  102 bits (255), Expect = 2e-22,   Method: Compositional matrix adjust.
 Identities = 51/116 (43%), Positives = 82/116 (70%), Gaps = 5/116 (4%)
 Frame = +3

Query: 343 DITSPHGIPL---DLLDRVMIIR--TMLYTPQEMKQIIKIRAQTEGINISEEALNHLGEI 397
           D+ +   +PL   D+  +  +I+  T+LY+  +M+QIIK+RAQTEG+ + E A + L EI
Sbjct: 423 DLETEEYVPLPKGDVHKKKEVIQDVTLLYSTSDMEQIIKLRAQTEGLQLEENAFSRLSEI 602

Query: 398 GTKTTLRYSVQLLTPANLLAKINGKDSIEKEHVEEISELFYDAKSSAKILADQQDK 453
           GT +TLRY+VQLLTPA  + K+NG++ I K+ ++++  LF DAK S+K L+++ +K
Sbjct: 603 GTSSTLRYAVQLLTPAYQMCKVNGRNLISKDDIDDVHSLFLDAKRSSKHLSEKNNK 770
>23413
          Length = 2343

 Score =  178 bits (451), Expect = 5e-45,   Method: Compositional matrix adjust.
 Identities = 83/170 (48%), Positives = 123/170 (72%)
 Frame = -3

Query: 286  YIDQGVAELVPGVLFVDEVHMLDIECFTYLHRALESSIAPIVIFASNRGNCVIRGTEDIT 345
            + ++G AE+VPGVLF+DEVHMLDIECF++L+RALE+ +AP++I A+NRG   IRGT  + 
Sbjct: 2341 WREEGKAEIVPGVLFIDEVHMLDIECFSFLNRALETDMAPVLIMATNRGITRIRGTHYM- 2165

Query: 346  SPHGIPLDLLDRVMIIRTMLYTPQEMKQIIKIRAQTEGINISEEALNHLGEIGTKTTLRY 405
            SPHG+P+DLLDR++II T  Y  +E+KQI+KIR + E + +S++AL  L +IG + +LRY
Sbjct: 2164 SPHGVPIDLLDRLLIISTTPYDEKEIKQILKIRCEEEDVEMSDDALTVLTKIGVEASLRY 1985

Query: 406  SVQLLTPANLLAKINGKDSIEKEHVEEISELFYDAKSSAKILADQQDKYM 455
            S+QL+T ANL+ +      +E E ++ +  LF D   S + L + Q  +M
Sbjct: 1984 SIQLITAANLVCRKRKGTEVEMEDIKRVYSLFLDESRSTQFLTEYQQAFM 1835
>39786
          Length = 467

 Score = 44.7 bits (104), Expect(2) = 5e-12,   Method: Compositional matrix adjust.
 Identities = 19/43 (44%), Positives = 31/43 (72%)
 Frame = +3

Query: 1   MKIEEVKSTTKTQRIASHSHVKGLGLDESGLAKQAASGLVGQE 43
           +K  EV+  T+ +RI +HSH++GLGLD+   A+  + G+VGQ+
Sbjct: 144 LKKYEVRDITRIERIGAHSHIRGLGLDDVLEARAVSQGMVGQK 272

 Score = 43.9 bits (102), Expect(2) = 5e-12,   Method: Compositional matrix adjust.
 Identities = 24/68 (35%), Positives = 40/68 (58%), Gaps = 3/68 (4%)
 Frame = +1

Query: 42  QENAREACGVIVELIKSKKMAGRAVLLAGPPGT---GKTALALAIAQELGSKVPFCPMVG 98
           +++AR A GV+V++++  K   R  L +         K  +A+ +AQ LG++ PF  M G
Sbjct: 268 KKDARRAAGVVVQMVREGK--NRRTLHSTSRRAEYRKKLPIAVGMAQALGTETPFTSMSG 441

Query: 99  SEVYSTEI 106
           SE+YS E+
Sbjct: 442 SEIYSLEM 465
>20270
          Length = 542

 Score = 40.0 bits (92), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 32/99 (32%), Positives = 52/99 (52%), Gaps = 1/99 (1%)
 Frame = -3

Query: 48  ACGVIVELIKSKKMAGRAVLLAGPPGTGKTALALAIAQELGSKVPFCPMVGSEVYSTEIK 107
           AC +   L + +K   R +LL GPPGTGK+ LA A+A E  +   F  +  S++ S  + 
Sbjct: 423 ACQISPSLHREEK-PWRGILLYGPPGTGKSYLAKAVATEANNST-FFSVSSSDLVSKWLG 250

Query: 108 KTEVLMEN-FRRAIGLRIKETKEVYEGEVTELTPCETEN 145
           ++E L++  F+ A   R  +   ++  EV  L    +EN
Sbjct: 249 ESEKLVKTLFQLA---RENQPSIIFIDEVDALCGSRSEN 142
>23766
          Length = 1463

 Score = 39.3 bits (90), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 21/47 (44%), Positives = 29/47 (61%)
 Frame = +1

Query: 55  LIKSKKMAGRAVLLAGPPGTGKTALALAIAQELGSKVPFCPMVGSEV 101
           L +    A + V+L GPPGTGKT LA A+A +  +   F  +VGSE+
Sbjct: 130 LRRDGNQAPKGVILYGPPGTGKTLLAKAVANQ--TSATFLRVVGSEL 264
>07243
          Length = 1112

 Score = 36.6 bits (83), Expect = 0.021,   Method: Compositional matrix adjust.
 Identities = 23/58 (39%), Positives = 32/58 (55%), Gaps = 3/58 (5%)
 Frame = +1

Query: 64  RAVLLAGPPGTGKTALALAIAQELGSKVPFCPMVGSEVYSTEIKKTEVL---MENFRR 118
           +  LL GPPGTGKT LA A+A +L +   F  +V S +    I ++  L   M N+ R
Sbjct: 310 KGCLLYGPPGTGKTLLARAVASQLDAN--FLKVVSSAIVDKYIGESARLIREMFNYAR 477
>19129
          Length = 1020

 Score = 36.6 bits (83), Expect = 0.023,   Method: Compositional matrix adjust.
 Identities = 19/38 (50%), Positives = 25/38 (65%)
 Frame = +1

Query: 64  RAVLLAGPPGTGKTALALAIAQELGSKVPFCPMVGSEV 101
           + VLL GPPGTGKT LA A+A    ++  F  + GSE+
Sbjct: 592 KGVLLYGPPGTGKTLLARAVAHH--TECTFIRVSGSEL 699
>01642
          Length = 1406

 Score = 36.2 bits (82), Expect = 0.025,   Method: Compositional matrix adjust.
 Identities = 19/37 (51%), Positives = 23/37 (62%)
 Frame = -1

Query: 64  RAVLLAGPPGTGKTALALAIAQELGSKVPFCPMVGSE 100
           R VL+ GPPG GKT LA A+A    +   F  +VGSE
Sbjct: 890 RGVLMYGPPGCGKTMLAKAVAHH--TTAAFIRVVGSE 786
>17843
          Length = 772

 Score = 36.2 bits (82), Expect = 0.025,   Method: Compositional matrix adjust.
 Identities = 15/25 (60%), Positives = 18/25 (72%)
 Frame = +1

Query: 63  GRAVLLAGPPGTGKTALALAIAQEL 87
            R +LL GPPGTGKT L  A+A +L
Sbjct: 184 NRVILLHGPPGTGKTTLCKALAHKL 258
>03022
          Length = 2255

 Score = 34.7 bits (78), Expect = 0.074,   Method: Compositional matrix adjust.
 Identities = 28/104 (26%), Positives = 49/104 (47%), Gaps = 1/104 (0%)
 Frame = +2

Query: 66   VLLAGPPGTGKTALALAIAQELGSKVPFCPMVGSEVYSTEIKKTEV-LMENFRRAIGLRI 124
            ++L GPPG GKT +A A+A E G  + F  + G E+    + ++E  L E F +A     
Sbjct: 1538 IILVGPPGCGKTLVAKAMANEAG--LNFIYIKGPELLDKYVGESERNLREKFDKAQAC-- 1705

Query: 125  KETKEVYEGEVTELTPCETENPMGGYGKTISHVIIGLKTAKGTK 168
                 ++  E+  L      N     GK++++ ++ L    G +
Sbjct: 1706 -APCLIFFDEMDTLCSNRQNNDGSNVGKSVTNQLLALMDGCGER 1834
>19561
          Length = 474

 Score = 33.9 bits (76), Expect = 0.14,   Method: Compositional matrix adjust.
 Identities = 23/73 (31%), Positives = 33/73 (45%)
 Frame = -1

Query: 51  VIVELIKSKKMAGRAVLLAGPPGTGKTALALAIAQELGSKVPFCPMVGSEVYSTEIKKTE 110
           V  EL   K+   +  LL GPPG GKT LA  +A+  G  V        E+ +++ +  E
Sbjct: 417 VSSELDDFKRPVQKVALLCGPPGLGKTTLAHIVAKHAGYNV-------VEMNASDDRSVE 259

Query: 111 VLMENFRRAIGLR 123
           V       A  +R
Sbjct: 258 VFSNKIEAATQMR 220
>26408
          Length = 463

 Score = 33.1 bits (74), Expect = 0.23,   Method: Compositional matrix adjust.
 Identities = 15/23 (65%), Positives = 17/23 (73%)
 Frame = +1

Query: 64  RAVLLAGPPGTGKTALALAIAQE 86
           + VLL GPPGTGKT LA A+A  
Sbjct: 367 KGVLLYGPPGTGKTLLARAVAHH 435
>27434
          Length = 472

 Score = 33.1 bits (74), Expect = 0.26,   Method: Compositional matrix adjust.
 Identities = 14/38 (36%), Positives = 23/38 (60%)
 Frame = +2

Query: 51  VIVELIKSKKMAGRAVLLAGPPGTGKTALALAIAQELG 88
           + V  +K+ ++ G  +   GPPG GKT++  +IA  LG
Sbjct: 125 LAVRQMKTTQLKGPILCFVGPPGVGKTSIGRSIATTLG 238
>09184
          Length = 1242

 Score = 28.9 bits (63), Expect = 4.3,   Method: Compositional matrix adjust.
 Identities = 20/54 (37%), Positives = 29/54 (53%), Gaps = 2/54 (3%)
 Frame = -3

Query: 39  LVGQENAREACGVIVELIKSKKMAGRA--VLLAGPPGTGKTALALAIAQELGSK 90
           LVG+E      G I++ + S    G A  + ++G PGTGKTA  L I  +  +K
Sbjct: 454 LVGRETE---VGEIMDFMTSHFDRGSAGSLYISGAPGTGKTAALLHIIDDFRTK 302
>15498
          Length = 769

 Score = 28.9 bits (63), Expect = 4.6,   Method: Compositional matrix adjust.
 Identities = 12/28 (42%), Positives = 20/28 (71%)
 Frame = -1

Query: 64  RAVLLAGPPGTGKTALALAIAQELGSKV 91
           +++LLAGP G+GK  L  A+  E+G+ +
Sbjct: 184 KSILLAGPRGSGKKMLVHALCNEVGANL 101
>01586
          Length = 1867

 Score = 28.9 bits (63), Expect = 4.8,   Method: Compositional matrix adjust.
 Identities = 15/54 (27%), Positives = 26/54 (48%), Gaps = 3/54 (5%)
 Frame = +2

Query: 386 ISEEALNHLGEIGTKTTLRYSVQLLTPANLLAKINGKD---SIEKEHVEEISEL 436
           I   AL   G++GTK  +RY       +N+  ++ G+D   ++   H E +  L
Sbjct: 437 IQSAALTSDGKVGTKAYMRYYDNPKEHSNMADQLGGQDGGATVSDHHAESVPRL 598
>30094
          Length = 341

 Score = 28.1 bits (61), Expect = 8.7,   Method: Compositional matrix adjust.
 Identities = 10/24 (41%), Positives = 18/24 (75%)
 Frame = +2

Query: 266 PKKTEITDKLRGEINKVVNKYIDQ 289
           P +TE T+ +  E+N +V+KY+D+
Sbjct: 11  PAETEYTETINKELNDIVHKYVDK 82
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|23956222|ref|NP_076224.1| ARP3 actin-related protein
3 homolog [Mus musculus]
         (418 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

00608                                                                 613   e-176
19721                                                                 208   6e-98
13361                                                                 333   6e-92
04742                                                                 251   3e-67
39562                                                                 210   1e-54
12322                                                                 124   7e-29
02757                                                                  74   4e-26
36954                                                                  93   2e-19
17032                                                                  81   6e-16
32273                                                                  80   1e-15
01436                                                                  75   4e-14
11487                                                                  44   2e-11
18926                                                                  63   2e-10
28457                                                                  32   0.38 
>00608
          Length = 1930

 Score =  613 bits (1581), Expect = e-176,   Method: Compositional matrix adjust.
 Identities = 299/337 (88%), Positives = 320/337 (94%)
 Frame = +3

Query: 82  IVEDWDLMERFMEQVIFKYLRAEPEDHYFLLTEPPLNTPENREYTAEIMFESFNVPGLYI 141
           I++DWDLMERF EQVIFKYLRAEPEDHYFLLTEPPLNTPENREYTAEIMFESFNVPGLYI
Sbjct: 3   IIDDWDLMERFYEQVIFKYLRAEPEDHYFLLTEPPLNTPENREYTAEIMFESFNVPGLYI 182

Query: 142 AVQAVLALAASWTSRQVGERTLTGTVIDSGDGVTHVIPVAEGYVIGSCIKHIPIAGRDIT 201
           AVQAVLALAASWTSR VGERTLTGTVIDSGDGVTHVIPVAEGYVIGSCIKHIPIAGRDIT
Sbjct: 183 AVQAVLALAASWTSRNVGERTLTGTVIDSGDGVTHVIPVAEGYVIGSCIKHIPIAGRDIT 362

Query: 202 YFIQQLLRDREVGIPPEQSLETAKAVKERYSYVCPDLVKEFNKYDTDGSKWIKQYTGVNA 261
           YFIQQLLR+REVGIPPEQSLETAKA+KER+SYVCPD+ KEF+KYDTD SKW+K+Y G N 
Sbjct: 363 YFIQQLLREREVGIPPEQSLETAKAIKERFSYVCPDIAKEFSKYDTDPSKWMKKYEGRNT 542

Query: 262 ISKKEFSIDVGYERFLGPEIFFHPEFANPDFTQPISEVVDEVIQNCPIDVRRPLYKNIVL 321
           ISK+ FS+DVGYERFLGPEIFFHPEF+NPDFT PIS+VVD+VIQNCPIDVRR LYKNIVL
Sbjct: 543 ISKQLFSVDVGYERFLGPEIFFHPEFSNPDFTMPISDVVDDVIQNCPIDVRRGLYKNIVL 722

Query: 322 SGGSTMFRDFGRRLQRDLKRTVDARLKLSEELSGGRLKPKPIDVQVITHHMQRYAVWFGG 381
           SGGSTMFRDFGR++QRD+KR VD RLK SEELS GR+KPKPI+VQVITHHMQRYAVWFGG
Sbjct: 723 SGGSTMFRDFGRKIQRDVKRVVDGRLKASEELSQGRIKPKPIEVQVITHHMQRYAVWFGG 902

Query: 382 SMLASTPEFYQVCHTKKDYEEIGPSICRHNPVFGVMS 418
           SMLASTPEFYQVCHTK DY+E GPSICRHNPVFG M+
Sbjct: 903 SMLASTPEFYQVCHTKADYDEHGPSICRHNPVFGTMA 1013
>19721
          Length = 757

 Score =  208 bits (529), Expect(2) = 6e-98,   Method: Compositional matrix adjust.
 Identities = 108/121 (89%), Positives = 114/121 (94%)
 Frame = +2

Query: 82  IVEDWDLMERFMEQVIFKYLRAEPEDHYFLLTEPPLNTPENREYTAEIMFESFNVPGLYI 141
           +VEDWDL ERFMEQ IFKYLRAEPEDHYFLLTEPPLNTPENRE+TAEIMFE+FN+PGLYI
Sbjct: 2   VVEDWDLHERFMEQAIFKYLRAEPEDHYFLLTEPPLNTPENREFTAEIMFETFNIPGLYI 181

Query: 142 AVQAVLALAASWTSRQVGERTLTGTVIDSGDGVTHVIPVAEGYVIGSCIKHIPIAGRDIT 201
           AVQAVLALAASWTSR   ERTLTGTVIDSGDGVTHVIPV +GYVIGS IKHIPIAGRDIT
Sbjct: 182 AVQAVLALAASWTSRPPNERTLTGTVIDSGDGVTHVIPVVDGYVIGSAIKHIPIAGRDIT 361

Query: 202 Y 202
           +
Sbjct: 362 F 364

 Score =  167 bits (424), Expect(2) = 6e-98,   Method: Compositional matrix adjust.
 Identities = 78/134 (58%), Positives = 95/134 (70%)
 Frame = +3

Query: 200 ITYFIQQLLRDREVGIPPEQSLETAKAVKERYSYVCPDLVKEFNKYDTDGSKWIKQYTGV 259
           I++F   +       IPP+ S+E AK +KERYSYVCPD+ KEF KYD+D  KWIK +   
Sbjct: 354 ISHFHPAIATGTGTVIPPDMSMEAAKQIKERYSYVCPDIAKEFAKYDSDPEKWIKAHKMS 533

Query: 260 NAISKKEFSIDVGYERFLGPEIFFHPEFANPDFTQPISEVVDEVIQNCPIDVRRPLYKNI 319
            +    +FS DVGYE+FLGPE+FF PEF N DF   IS+VVD VIQ+CPID RRPLY NI
Sbjct: 534 GSSKYPDFSFDVGYEKFLGPEVFFRPEFVNGDFQASISDVVDTVIQSCPIDSRRPLYNNI 713

Query: 320 VLSGGSTMFRDFGR 333
           VLSGGS+MF+   R
Sbjct: 714 VLSGGSSMFKHLDR 755
>13361
          Length = 1217

 Score =  333 bits (855), Expect = 6e-92,   Method: Compositional matrix adjust.
 Identities = 148/186 (79%), Positives = 169/186 (90%)
 Frame = +3

Query: 233 YVCPDLVKEFNKYDTDGSKWIKQYTGVNAISKKEFSIDVGYERFLGPEIFFHPEFANPDF 292
           Y+CPD+ KEF KYD++ SKWI+ YTG+N ++K+ F++DVGYERFLGPEIFFHPEF+NPDF
Sbjct: 45  YICPDIAKEFAKYDSEPSKWIRNYTGMNTVTKQAFNVDVGYERFLGPEIFFHPEFSNPDF 224

Query: 293 TQPISEVVDEVIQNCPIDVRRPLYKNIVLSGGSTMFRDFGRRLQRDLKRTVDARLKLSEE 352
           T P+SE+VD VIQNCPIDVRR LY NIVLSGGSTMF+DFGRRLQRD+KR+VD RL++SE 
Sbjct: 225 TIPLSEIVDNVIQNCPIDVRRHLYNNIVLSGGSTMFKDFGRRLQRDIKRSVDTRLRISEN 404

Query: 353 LSGGRLKPKPIDVQVITHHMQRYAVWFGGSMLASTPEFYQVCHTKKDYEEIGPSICRHNP 412
           LS GR+KPKPIDVQVITHHMQRYAVWFGGSMLASTPEFYQVCHTK  YEE GPSICRHNP
Sbjct: 405 LSEGRIKPKPIDVQVITHHMQRYAVWFGGSMLASTPEFYQVCHTKAAYEEYGPSICRHNP 584

Query: 413 VFGVMS 418
           VFG M+
Sbjct: 585 VFGTMT 602
>04742
          Length = 2111

 Score =  251 bits (642), Expect = 3e-67,   Method: Compositional matrix adjust.
 Identities = 149/411 (36%), Positives = 214/411 (52%), Gaps = 1/411 (0%)
 Frame = +2

Query: 5   LPACVVDCGTGYTKLGYAGNTEPQFIIPSCIAIKESAKVGDQAQRRVMKGVDDLDFFIGD 64
           + A V+D G+G  K G+AG+  P+ + PS         VG    + VM G+   D ++GD
Sbjct: 107 VAALVIDNGSGMCKAGFAGDDAPRAVFPSI--------VGRPRHQGVMVGMGQKDSYVGD 262

Query: 65  EAIEKPTYAT-KWPIRHGIVEDWDLMERFMEQVIFKYLRAEPEDHYFLLTEPPLNTPENR 123
           EA  K    T K+PI HGIV +WD ME+      +  LR  PE+H  LLTE PLN   NR
Sbjct: 263 EAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANR 442

Query: 124 EYTAEIMFESFNVPGLYIAVQAVLALAASWTSRQVGERTLTGTVIDSGDGVTHVIPVAEG 183
           E   +IMFE+FN P +Y+A+QAVL+L AS  +        TG V+DSGDGV H +P+ EG
Sbjct: 443 EKMTQIMFETFNSPAMYVAIQAVLSLYASGRT--------TGIVLDSGDGVXHTVPIYEG 598

Query: 184 YVIGSCIKHIPIAGRDITYFIQQLLRDREVGIPPEQSLETAKAVKERYSYVCPDLVKEFN 243
           Y +   I  + +AGRD+T ++ ++L +R          E  + +KE+  YV  D  +E  
Sbjct: 599 YALPHAISRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEM- 775

Query: 244 KYDTDGSKWIKQYTGVNAISKKEFSIDVGYERFLGPEIFFHPEFANPDFTQPISEVVDEV 303
           +     S   K Y   +        I +G ERF  PE  F P F   + +    E     
Sbjct: 776 QTAASSSSLEKSYELPDGQ-----VITIGNERFRCPEAMFQPSFLGME-SAGXHETTYNS 937

Query: 304 IQNCPIDVRRPLYKNIVLSGGSTMFRDFGRRLQRDLKRTVDARLKLSEELSGGRLKPKPI 363
           I  C +D+R+ LY N VLSGGSTM+     R+Q+++                  L P  +
Sbjct: 938 IMKCDVDIRKDLYANTVLSGGSTMYPGIADRMQKEIT----------------ALAPPTM 1069

Query: 364 DVQVITHHMQRYAVWFGGSMLASTPEFYQVCHTKKDYEEIGPSICRHNPVF 414
            +++I    ++Y+VW GGS+LAS   F Q+  +K++Y+E GPSI  H   F
Sbjct: 1070KIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIV-HRKCF 1219
>39562
          Length = 1438

 Score =  210 bits (534), Expect = 1e-54,   Method: Compositional matrix adjust.
 Identities = 122/333 (36%), Positives = 174/333 (52%)
 Frame = -2

Query: 82   IVEDWDLMERFMEQVIFKYLRAEPEDHYFLLTEPPLNTPENREYTAEIMFESFNVPGLYI 141
            IV +WD ME+      +  LR  PE+H  LLTE PLN   NRE   +IMFE+FN P +Y+
Sbjct: 1437 IVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNSPAMYV 1258

Query: 142  AVQAVLALAASWTSRQVGERTLTGTVIDSGDGVTHVIPVAEGYVIGSCIKHIPIAGRDIT 201
            A+QAVL+L AS  +        TG V+DSGDGVTH +P+ EGY +   I  + +AGRD+T
Sbjct: 1257 AIQAVLSLYASGRT--------TGIVLDSGDGVTHTVPIYEGYALPHAIMRLDLAGRDLT 1102

Query: 202  YFIQQLLRDREVGIPPEQSLETAKAVKERYSYVCPDLVKEFNKYDTDGSKWIKQYTGVNA 261
             ++ ++L +R          E  + +KE+  YV  D  +E        S   K Y   + 
Sbjct: 1101 DYLMKILTERGYSFTTTAEREIVRDIKEKLDYVALDFEQEMLT-AASSSSLEKSYELPDG 925

Query: 262  ISKKEFSIDVGYERFLGPEIFFHPEFANPDFTQPISEVVDEVIQNCPIDVRRPLYKNIVL 321
                   I +G ERF  PE  F P F   + +  I E     I  C +D+R+ LY N VL
Sbjct: 924  Q-----VITIGNERFRCPEAMFQPSFLGME-SAGIHETTYNSIMKCDVDIRKDLYANTVL 763

Query: 322  SGGSTMFRDFGRRLQRDLKRTVDARLKLSEELSGGRLKPKPIDVQVITHHMQRYAVWFGG 381
            SGGSTM+     R+Q+++                  L P  + +++I    ++Y+VW GG
Sbjct: 762  SGGSTMYPGIADRMQKEIT----------------ALAPPTMKIKIIAPPERKYSVWIGG 631

Query: 382  SMLASTPEFYQVCHTKKDYEEIGPSICRHNPVF 414
            S+LAS   F Q+  +K++Y+E GPSI  H   F
Sbjct: 630  SILASLSTFQQMWISKQEYDESGPSIV-HRKCF 535
>12322
          Length = 849

 Score =  124 bits (311), Expect = 7e-29,   Method: Compositional matrix adjust.
 Identities = 76/231 (32%), Positives = 119/231 (51%)
 Frame = +1

Query: 174 VTHVIPVAEGYVIGSCIKHIPIAGRDITYFIQQLLRDREVGIPPEQSLETAKAVKERYSY 233
           VTH +PV EG+ +   I  + +AGRD+T +++ LLR   + +      E  K +KER  Y
Sbjct: 1   VTHAVPVYEGFAMPHSIMRVDVAGRDVTRYLRLLLRKEGMDLHTTAEFEVVKHIKERTCY 180

Query: 234 VCPDLVKEFNKYDTDGSKWIKQYTGVNAISKKEFSIDVGYERFLGPEIFFHPEFANPDFT 293
           +  + +KE    DT+          V+       +++VG  RF  PE+ F P+    +  
Sbjct: 181 LSINPLKE-ESVDTEK---------VSYTLPDGNTVEVGPARFRAPELLFRPDLIGEE-C 327

Query: 294 QPISEVVDEVIQNCPIDVRRPLYKNIVLSGGSTMFRDFGRRLQRDLKRTVDARLKLSEEL 353
           + I EV+   IQ   +D+R+ LY NIVLSGGST+F+ FG RL  +LK             
Sbjct: 328 EGIHEVLSYSIQKSDVDLRKTLYSNIVLSGGSTLFKGFGDRLLSELK------------- 468

Query: 354 SGGRLKPKPIDVQVITHHMQRYAVWFGGSMLASTPEFYQVCHTKKDYEEIG 404
              +L PK I +++     + Y+ W G S+LAS   F ++  +K++Y E G
Sbjct: 469 ---KLAPKDIKIRISAPQERLYSTWIGXSILASLDTFRKMWVSKREYHEEG 612
>02757
          Length = 1094

 Score = 73.9 bits (180), Expect(3) = 4e-26,   Method: Compositional matrix adjust.
 Identities = 47/152 (30%), Positives = 71/152 (46%)
 Frame = -2

Query: 188 SCIKHIPIAGRDITYFIQQLLRDREVGIPPEQSLETAKAVKERYSYVCPDLVKEFNKYDT 247
           + I  + +AGRD+T ++ ++L +R          E    +KE+  YV  D  +E      
Sbjct: 994 TAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVXDIKEKLCYVALDFEQEMATA-A 818

Query: 248 DGSKWIKQYTGVNAISKKEFSIDVGYERFLGPEIFFHPEFANPDFTQPISEVVDEVIQNC 307
             S   K Y   +        I +G ERF  PE  F P F   + +  I E     I  C
Sbjct: 817 SSSSLEKSYELPDG-----QVITIGNERFRCPESLFQPSFLGME-SAGIHETTYNSIMKC 656

Query: 308 PIDVRRPLYKNIVLSGGSTMFRDFGRRLQRDL 339
            +D+R+ LY N VLSGG+TMF     R+Q+++
Sbjct: 655 DVDIRKDLYANTVLSGGTTMFPGIADRMQKEI 560

 Score = 43.9 bits (102), Expect(3) = 4e-26,   Method: Compositional matrix adjust.
 Identities = 19/45 (42%), Positives = 31/45 (68%)
 Frame = -3

Query: 363 IDVQVITHHMQRYAVWFGGSMLASTPEFYQVCHTKKDYEEIGPSI 407
           + ++ I    ++Y+VW GGS+LAS   F Q+  +K++Y+E GPSI
Sbjct: 537 MKIKXIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSI 403

 Score = 38.1 bits (87), Expect(3) = 4e-26,   Method: Compositional matrix adjust.
 Identities = 15/23 (65%), Positives = 19/23 (82%)
 Frame = -1

Query: 164  TGTVIDSGDGVTHVIPVAEGYVI 186
            TG V+DSGDGVTH +P+ EGY +
Sbjct: 1067 TGIVLDSGDGVTHTVPIYEGYAL 999
>36954
          Length = 892

 Score = 93.2 bits (230), Expect = 2e-19,   Method: Compositional matrix adjust.
 Identities = 59/226 (26%), Positives = 106/226 (46%), Gaps = 2/226 (0%)
 Frame = -1

Query: 7   ACVVDCGTGYTKLGYAGNTEPQFIIPSCIAIKESAKVGDQAQRRVMKGVDDLDFFIGDEA 66
           A V D G+   + GYAG   P+  IP+ + + E  +              +  + I    
Sbjct: 805 ALVFDIGSYSFRAGYAGEDTPKAEIPTHVGVMEDIETTMDTDGGDAPPQPEKKYLIDTVY 626

Query: 67  IEKPTYATKWP--IRHGIVEDWDLMERFMEQVIFKYLRAEPEDHYFLLTEPPLNTPENRE 124
           ++ P         ++ G+VEDWD+ E+ ++    + +++E   H  L++EP  NT   RE
Sbjct: 625 MKHPRKGMHLNSFLKDGMVEDWDMFEKVIDYAYNRSIKSESCLHPLLMSEPAWNTKAKRE 446

Query: 125 YTAEIMFESFNVPGLYIAVQAVLALAASWTSRQVGERTLTGTVIDSGDGVTHVIPVAEGY 184
              EIMFE +N+P  ++   +VL+  A+  S        T  ++DSG   T  +PV +GY
Sbjct: 445 KLTEIMFEKYNIPAFFLRKNSVLSAFANGRS--------TALILDSGATHTSAVPVYDGY 290

Query: 185 VIGSCIKHIPIAGRDITYFIQQLLRDREVGIPPEQSLETAKAVKER 230
           V+   I   P+AG  I      L+ ++ + + P   + + + V ++
Sbjct: 289 VLTQGIVKSPLAGDFIARECGLLMEEQNIEVVPPYLISSKEVVADK 152
>17032
          Length = 2938

 Score = 81.3 bits (199), Expect = 6e-16,   Method: Compositional matrix adjust.
 Identities = 35/40 (87%), Positives = 37/40 (92%)
 Frame = -1

Query: 379  FGGSMLASTPEFYQVCHTKKDYEEIGPSICRHNPVFGVMS 418
            FGGSMLASTPEFYQVCHTK DY+E GPSICRHNPVFG M+
Sbjct: 2938 FGGSMLASTPEFYQVCHTKADYDEHGPSICRHNPVFGTMA 2819
>32273
          Length = 265

 Score = 80.5 bits (197), Expect = 1e-15,   Method: Compositional matrix adjust.
 Identities = 40/81 (49%), Positives = 57/81 (70%), Gaps = 1/81 (1%)
 Frame = -2

Query: 73  ATKWPIRHGIVEDWDLMERFMEQVIFK-YLRAEPEDHYFLLTEPPLNTPENREYTAEIMF 131
           + ++P+ HGIV+DW+ MER  + +  K  L+   E+H  LLTE PLN   NRE  AEI F
Sbjct: 258 SIRYPMEHGIVKDWNDMERIWQYIYSKDQLQTFSEEHPVLLTEAPLNPRRNREKAAEIFF 79

Query: 132 ESFNVPGLYIAVQAVLALAAS 152
           ++FNVP L+I++QAVL+L A+
Sbjct: 78  DTFNVPALFISMQAVLSLYAT 16
>01436
          Length = 2563

 Score = 75.5 bits (184), Expect = 4e-14,   Method: Compositional matrix adjust.
 Identities = 61/213 (28%), Positives = 101/213 (47%), Gaps = 4/213 (1%)
 Frame = +3

Query: 200 ITYFIQQLLRDREVGIPPEQSLETAKAVKERYSYVCPDLVKEFNKYDTDGSKWIKQYTGV 259
           IT ++ +LL  R          ET + +KE+  Y   D+ +E  K   + +  ++ Y   
Sbjct: 3   ITRYLIKLLLLRGYAFNHSADFETVRMLKEKLCYTAYDVEQE-QKLALETTVLVEPY--- 170

Query: 260 NAISKKEFSIDVGYERFLGPEIFFHPEFANPDFTQPISEVVDEVIQNCPIDVRRPLYKNI 319
             I      I VG ERF  PE  F P   N D    ++E++   IQ   +D+R   YK+I
Sbjct: 171 --ILPDGRVIKVGGERFEAPEALFQPHLINVDGVG-VAELLFNTIQAADMDIRPDFYKHI 341

Query: 320 VLSGGSTMFRDFGRRLQRDLKRTVDARLKLSEELSGGRLKPKPIDVQVITHHMQRYAVWF 379
           VLSGGSTM+     RL+R++K     +L L   L G   +     +++     +++ V+ 
Sbjct: 342 VLSGGSTMYPGLPSRLEREIK-----QLYLERVLXGDTSRLSKFKIRIEDPPRRKHMVFL 506

Query: 380 GGSMLAST----PEFYQVCHTKKDYEEIGPSIC 408
           GGS+ A       +F+ +   + +YEE+G  + 
Sbjct: 507 GGSVXADIMKDKDDFWMM---RSEYEEMGVKVL 596
>11487
          Length = 771

 Score = 43.5 bits (101), Expect(2) = 2e-11,   Method: Compositional matrix adjust.
 Identities = 17/35 (48%), Positives = 24/35 (68%)
 Frame = -1

Query: 304 IQNCPIDVRRPLYKNIVLSGGSTMFRDFGRRLQRD 338
           I  C +D+R+ LY N VLSGG+TMF     R+Q++
Sbjct: 753 IMKCDVDIRKDLYANTVLSGGTTMFPGIADRMQKE 649

 Score = 42.7 bits (99), Expect(2) = 2e-11,   Method: Compositional matrix adjust.
 Identities = 18/35 (51%), Positives = 27/35 (77%)
 Frame = -2

Query: 373 QRYAVWFGGSMLASTPEFYQVCHTKKDYEEIGPSI 407
           ++Y+VW GGS+LAS   F Q+  +K++Y+E GPSI
Sbjct: 596 RKYSVWIGGSILASLSTFQQMWISKQEYDESGPSI 492
>18926
          Length = 478

 Score = 63.2 bits (152), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 37/124 (29%), Positives = 58/124 (46%), Gaps = 2/124 (1%)
 Frame = +1

Query: 285 PEFANPDFTQ--PISEVVDEVIQNCPIDVRRPLYKNIVLSGGSTMFRDFGRRLQRDLKRT 342
           P   NP  T    +  VV   +  C ID+R  LY  ++  GG+++ + F  RL RDL   
Sbjct: 61  PSSRNPKATPVLGVGHVVTTSVGMCDIDIRPSLYGGVIAVGGNSLIQGFTERLNRDLSNK 240

Query: 343 VDARLKLSEELSGGRLKPKPIDVQVITHHMQRYAVWFGGSMLASTPEFYQVCHTKKDYEE 402
               ++L               +   +   +R++ W GGS+LAS   F Q+  +K++YEE
Sbjct: 241 TPPSMRLK-------------IIAAASTAERRFSSWIGGSILASLGSFQQMWVSKQEYEE 381

Query: 403 IGPS 406
            G S
Sbjct: 382 GGKS 393
>28457
          Length = 926

 Score = 32.3 bits (72), Expect = 0.38,   Method: Compositional matrix adjust.
 Identities = 15/39 (38%), Positives = 24/39 (61%), Gaps = 2/39 (5%)
 Frame = -2

Query: 271 VGYERF--LGPEIFFHPEFANPDFTQPISEVVDEVIQNC 307
           VGY R   + P +FF P F+ P FT   S++ ++V++ C
Sbjct: 925 VGYLRHVPISPSLFFRPSFSXPLFTASSSKLREKVLEIC 809
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|28478945|ref|XP_129846.3| PREDICTED: glutaminase
isoform 1 [Mus musculus]
         (674 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

05396                                                                 614   e-176
26615                                                                  31   1.7  
>05396
          Length = 1865

 Score =  614 bits (1583), Expect = e-176,   Method: Compositional matrix adjust.
 Identities = 285/513 (55%), Positives = 381/513 (74%), Gaps = 3/513 (0%)
 Frame = +3

Query: 144 LEDLLFYTIAEGQEKIPVHKFITALKSTGLRTSDPRLKECMDMLRLTLQTTSDG---VML 200
           +E  +F  +++   K+ ++KF+ ALK TGLR SDPRL E M  L  ++ +  DG   V L
Sbjct: 33  VEGAIFDYLSDSDGKLSLNKFLGALKETGLRVSDPRLAESMRNLGNSITSEFDGATNVTL 212

Query: 201 DKDLFKKCVQSNIVLLTQAFRRKFVIPDFMSFTSHIDELYESAKKQSGGKVADYIPQLAK 260
           D+  FK CV  NIVL+ +AFRR+F++P+F  F  HIDELY +AK  + G++A YIPQLA+
Sbjct: 213 DRHTFKSCVTDNIVLIARAFRRQFIVPEFQEFCRHIDELYWNAKPLTEGQLATYIPQLAR 392

Query: 261 FSPDLWGVSVCTVDGQRHSIGDTKVPFCLQSCVKPLKYAIAVNDLGTEYVHRYVGKEPSG 320
            +PD WG+SVCTVDGQR+S+GD  +PFCLQS  KPL YA+A+ND+  + VH+YVG+EPSG
Sbjct: 393 INPDYWGLSVCTVDGQRYSLGDANIPFCLQSISKPLTYALALNDVEPDVVHQYVGQEPSG 572

Query: 321 LRFNKLFLNEDDKPHNPMVNAGAIVVTSLIKQGVNNAEKFDYVMQFLNKMAGNEYVGFSN 380
            RFN + LN  +KPHNPMVNAGAIV+TS++K  +N +++FDY +++  ++AG+E+V F+N
Sbjct: 573 QRFNDIGLNMYNKPHNPMVNAGAIVMTSVVKPELNLSDRFDYALRYFKRLAGDEFVSFNN 752

Query: 381 ATFQSERESGDRNFAIGYYLKEKKCFPEGTDMVGILDFYFQLCSIEVTCESASVMAATLA 440
           + F SER++ DRNFAI YYLKE +CFP+GT+++ +LDFYFQLCS+E+TC+S +V AATLA
Sbjct: 753 SVFLSERDTADRNFAIAYYLKENQCFPKGTNIMEVLDFYFQLCSVEMTCDSGAVAAATLA 932

Query: 441 NGGFCPITGERVLSPEAVRNTLSLMHSCGMYDFSGQFAFHVGLPAKSGVAGGILLVVPNV 500
           NGG CPIT ++VL P  +R+TLSLM SCGMYD+SGQFAF VGLP KSGVAGGI+LVVPNV
Sbjct: 933 NGGICPITDDKVLEPFCIRDTLSLMLSCGMYDYSGQFAFKVGLPGKSGVAGGIMLVVPNV 1112

Query: 501 MGMMCWSPPLDKMGNSVKGIHFCHDLVSLCNFHNYDNLRHFAKKLDPRREGGDQRVKSVI 560
           MG+M WSPPLD  GNS++GI FC DLV   NFHN+DN+R   +KLDP     + +   ++
Sbjct: 1113MGIMMWSPPLDGYGNSMRGIKFCKDLVHSFNFHNFDNIRFTTRKLDPCVRHMELQANRIV 1292

Query: 561 NLLFAAYTGDVSALRRFALSAMDMEQRDYDSRTXXXXXXXXXXXXXXKFLLEACKVNPFP 620
           +LLF+AY GDV+A+RR ALS MDM Q DYD RT              +FLL+ CK +PF 
Sbjct: 1293DLLFSAYNGDVTAIRRCALSGMDMSQPDYDGRTALHVASAEGQLQVVEFLLDRCKCSPFL 1472

Query: 621 KDRWNNTPMDEALHFGHHDVFKILQEYQVQYTP 653
            DRW  TP+D+A+ F  H+  ++L+E  +Q  P
Sbjct: 1473VDRWGFTPLDDAVRFEKHEAAELLKERMMQENP 1571
>26615
          Length = 973

 Score = 30.8 bits (68), Expect = 1.7,   Method: Compositional matrix adjust.
 Identities = 18/51 (35%), Positives = 27/51 (52%), Gaps = 2/51 (3%)
 Frame = +1

Query: 334 PHNPMVNAGAIVVTSLIKQGVNNAEKFDYVMQFLNKMAGNE--YVGFSNAT 382
           P +    A ++V TSL  +G++    + YVMQFLN    +   Y  F +AT
Sbjct: 256 PVHTTTAAPSMVSTSLXSRGISWINAYFYVMQFLNLTDSDRVNYTDFVSAT 408
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|27754103|ref|NP_080235.2| proteasome 26S ATPase
subunit 6 [Mus musculus]
         (389 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

07243                                                                 609   e-175
07247                                                                 400   e-132
19129                                                                 283   6e-77
01642                                                                 260   9e-76
23766                                                                 236   2e-62
02582                                                                 173   9e-44
03022                                                                 157   8e-39
12235                                                                 138   3e-33
00810                                                                 129   2e-30
20270                                                                 108   3e-24
38672                                                                  82   7e-22
25671                                                                  82   4e-16
26408                                                                  74   7e-14
02194                                                                  66   2e-11
17843                                                                  55   6e-08
06766                                                                  51   1e-06
26887                                                                  45   7e-05
14413                                                                  42   4e-04
27434                                                                  37   0.012
37695                                                                  35   0.037
01279                                                                  35   0.047
19561                                                                  35   0.062
24645                                                                  28   7.0  
>07243
          Length = 1112

 Score =  609 bits (1571), Expect = e-175,   Method: Compositional matrix adjust.
 Identities = 295/325 (90%), Positives = 311/325 (95%)
 Frame = +1

Query: 65  TEEKFIVKATNGPRYVVGCRRQLDKSKLKPGTRVALDMTTLTIMRYLPREVDPLVYNMSH 124
           TE+KFIVKATNGPRYVVGCRRQLDK+KLK GTRVALDMTTLTIMRYLPREVDPLVYNMSH
Sbjct: 1   TEDKFIVKATNGPRYVVGCRRQLDKAKLKSGTRVALDMTTLTIMRYLPREVDPLVYNMSH 180

Query: 125 EDPGNVSYSEIGGLSEQIRELREVIELPLTNPELFQRVGIIPPKGCLLYGPPGTGKTLLA 184
           EDPG+V+YS IGGL+EQIRELREVIELPL NPELF RVGI PPKGCLLYGPPGTGKTLLA
Sbjct: 181 EDPGDVTYSAIGGLTEQIRELREVIELPLLNPELFLRVGITPPKGCLLYGPPGTGKTLLA 360

Query: 185 RAVASQLDCNFLKVVSSSIVDKYIGESARLIREMFNYARDHQPCIIFMDEIDAIGGRRFS 244
           RAVASQLD NFLKVVSS+IVDKYIGESARLIREMFNYARDHQPCIIFMDEIDAIGGRRFS
Sbjct: 361 RAVASQLDANFLKVVSSAIVDKYIGESARLIREMFNYARDHQPCIIFMDEIDAIGGRRFS 540

Query: 245 EGTSADREIQRTLMELLNQMDGFDTLHRVKMIMATNRPDTLDPALLRPGRLDRKIHIDLP 304
           EGTSADREIQRTLMELLNQMDGFD+L +VKMIMATNRPDTLDPALLRPGRLDRKI I LP
Sbjct: 541 EGTSADREIQRTLMELLNQMDGFDSLGQVKMIMATNRPDTLDPALLRPGRLDRKIEIPLP 720

Query: 305 NEQARLDILKIHAGPITKHGEIDYEAIVKLSDGFNGADLRNVCTEAGMFAIRADHDFVVQ 364
           NEQARL+ILKIHA  I KHGEIDYEAIVKLSD FNGADLRNVCTEAG+FAIRA+ ++V+Q
Sbjct: 721 NEQARLEILKIHALIIAKHGEIDYEAIVKLSDNFNGADLRNVCTEAGLFAIRAEREYVIQ 900

Query: 365 EDFMKAVRKVADSKKLESKLDYKPV 389
           EDFMKAVRKV+D+KKLESKLDYKPV
Sbjct: 901 EDFMKAVRKVSDNKKLESKLDYKPV 975
>07247
          Length = 1753

 Score =  400 bits (1029), Expect(2) = e-132,   Method: Compositional matrix adjust.
 Identities = 191/214 (89%), Positives = 205/214 (95%)
 Frame = -2

Query: 176  PGTGKTLLARAVASQLDCNFLKVVSSSIVDKYIGESARLIREMFNYARDHQPCIIFMDEI 235
            PGTGKTLLARAVASQLDCNFLKVVSS+IVDKYIGESARLIREMF +ARDH+PCIIFMDEI
Sbjct: 1407 PGTGKTLLARAVASQLDCNFLKVVSSAIVDKYIGESARLIREMFAFARDHEPCIIFMDEI 1228

Query: 236  DAIGGRRFSEGTSADREIQRTLMELLNQMDGFDTLHRVKMIMATNRPDTLDPALLRPGRL 295
            DAIGGRRFSEGTSADREIQRTLMELLNQMDGFD L +VKMIMATNRPDTLDPALLRPGRL
Sbjct: 1227 DAIGGRRFSEGTSADREIQRTLMELLNQMDGFDALGQVKMIMATNRPDTLDPALLRPGRL 1048

Query: 296  DRKIHIDLPNEQARLDILKIHAGPITKHGEIDYEAIVKLSDGFNGADLRNVCTEAGMFAI 355
            DRKI I LPNEQARL+ILKIHA PI KHGEID+EA+VKLS+ FNGADLRNVCTEAGMFAI
Sbjct: 1047 DRKIEISLPNEQARLEILKIHANPIAKHGEIDWEAVVKLSEDFNGADLRNVCTEAGMFAI 868

Query: 356  RADHDFVVQEDFMKAVRKVADSKKLESKLDYKPV 389
            RA+ D+V++EDFMKAVRKV+D+KKLESKLDYKPV
Sbjct: 867  RAERDYVIEEDFMKAVRKVSDNKKLESKLDYKPV 766

 Score = 89.0 bits (219), Expect(2) = e-132,   Method: Compositional matrix adjust.
 Identities = 39/50 (78%), Positives = 47/50 (94%)
 Frame = -1

Query: 115  VDPLVYNMSHEDPGNVSYSEIGGLSEQIRELREVIELPLTNPELFQRVGI 164
            +DPLVYNMS EDPG++++++IGGL EQ+RELREVIELPL NPELFQRVGI
Sbjct: 1588 MDPLVYNMSVEDPGDITFNQIGGLGEQVRELREVIELPLLNPELFQRVGI 1439

 Score = 29.6 bits (65), Expect = 2.5,   Method: Compositional matrix adjust.
 Identities = 12/21 (57%), Positives = 13/21 (61%)
 Frame = -3

Query: 156  PELFQRVGIIPPKGCLLYGPP 176
            P      G  PPKGCLL+GPP
Sbjct: 1466 PRAVPACGHHPPKGCLLFGPP 1404
>19129
          Length = 1020

 Score =  283 bits (725), Expect = 6e-77,   Method: Compositional matrix adjust.
 Identities = 138/265 (52%), Positives = 187/265 (70%)
 Frame = +1

Query: 46  DLKALQSVGQIVGEVLKQLTEEKFIVKATNGPRYVVGCRRQLDKSKLKPGTRVALDMTTL 105
           +L+ LQ  G  VGEV+K + ++K +VK     ++VV   + +D + + P  RVAL   + 
Sbjct: 226 ELQLLQEQGSYVGEVVKPMDKKKVLVKVHPEGKFVVDIDKNIDMNSVTPNCRVALRNDSY 405

Query: 106 TIMRYLPREVDPLVYNMSHEDPGNVSYSEIGGLSEQIRELREVIELPLTNPELFQRVGII 165
            + + LP +VDPLV  M  E   + +Y  +GGL +QI+E++EVIELP+ +PELF+ +GI 
Sbjct: 406 VLHKILPNKVDPLVSLMMVEKVPDSTYEMVGGLDKQIKEIKEVIELPVKHPELFEALGIA 585

Query: 166 PPKGCLLYGPPGTGKTLLARAVASQLDCNFLKVVSSSIVDKYIGESARLIREMFNYARDH 225
            PKG LLYGPPGTGKTLLARAVA   +C F++V  S +V K+IGE +R++RE+F  AR+H
Sbjct: 586 QPKGVLLYGPPGTGKTLLARAVAHHTECTFIRVSGSELVQKFIGEGSRMVRELFVMAREH 765

Query: 226 QPCIIFMDEIDAIGGRRFSEGTSADREIQRTLMELLNQMDGFDTLHRVKMIMATNRPDTL 285
            P IIFMDEID+IG  R   G+  D E+QRT++ELLNQ+DGF+    +K+IMATNR D L
Sbjct: 766 APSIIFMDEIDSIGSSRLEGGSGGDSEVQRTMLELLNQLDGFEPKQNIKVIMATNRIDIL 945

Query: 286 DPALLRPGRLDRKIHIDLPNEQARL 310
           D ALLRPGR+DRKI    PNE+ARL
Sbjct: 946 DSALLRPGRIDRKIEFPPPNEEARL 1020
>01642
          Length = 1406

 Score =  260 bits (665), Expect(2) = 9e-76,   Method: Compositional matrix adjust.
 Identities = 129/255 (50%), Positives = 176/255 (69%)
 Frame = -1

Query: 132 YSEIGGLSEQIRELREVIELPLTNPELFQRVGIIPPKGCLLYGPPGTGKTLLARAVASQL 191
           YS+IGG+  Q +E+RE +ELPLT+ EL++++GI PP+G L+YGPPG GKT+LA+AVA   
Sbjct: 998 YSDIGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAKAVAHHT 819

Query: 192 DCNFLKVVSSSIVDKYIGESARLIREMFNYARDHQPCIIFMDEIDAIGGRRFSEGTSADR 251
              F++VV S  V KY+GE  R++R++F  A+++ P IIF+DEIDAI  +RF   T ADR
Sbjct: 818 TAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRFDAQTGADR 639

Query: 252 EIQRTLMELLNQMDGFDTLHRVKMIMATNRPDTLDPALLRPGRLDRKIHIDLPNEQARLD 311
           E+QR L+ELLNQMDGFD    VK+IMATNR DTLDPALLRPGRLDRKI   LP+ + +  
Sbjct: 638 EVQRILLELLNQMDGFDQTVNVKVIMATNRADTLDPALLRPGRLDRKIEFPLPDRRQKRL 459

Query: 312 ILKIHAGPITKHGEIDYEAIVKLSDGFNGADLRNVCTEAGMFAIRADHDFVVQEDFMKAV 371
           I     G +    E+D E  V   D  +GAD+  +C EAGM A+R +   V+ +DF K  
Sbjct: 458 IFSTITGKMNISEEVDLEDYVARPDKISGADINAICQEAGMQAVRENRYVVLAKDFEKGY 279

Query: 372 RKVADSKKLESKLDY 386
           +   + KK E++ ++
Sbjct: 278 KN--NIKKDETEHEF 240

 Score = 41.6 bits (96), Expect(2) = 9e-76,   Method: Compositional matrix adjust.
 Identities = 22/73 (30%), Positives = 40/73 (54%)
 Frame = -2

Query: 40   YEKSENDLKALQSVGQIVGEVLKQLTEEKFIVKATNGPRYVVGCRRQLDKSKLKPGTRVA 99
            Y  ++ ++K +QSV  ++G+ L+ + +   IV +T G  Y V     +D+  LKP + VA
Sbjct: 1276 YLHAQEEVKRIQSVPLVIGQFLEAVDQNTGIVGSTTGSNYYVRILSTIDRELLKPSSSVA 1097

Query: 100  LDMTTLTIMRYLP 112
            L   +  ++  LP
Sbjct: 1096 LHKHSNALVDVLP 1058
>23766
          Length = 1463

 Score =  236 bits (601), Expect = 2e-62,   Method: Compositional matrix adjust.
 Identities = 117/255 (45%), Positives = 164/255 (64%)
 Frame = +1

Query: 120 YNMSHEDPGNVSYSEIGGLSEQIRELREVIELPLTNPELFQRVGIIPPKGCLLYGPPGTG 179
           +   H DPGN          + IR         + +  + +R G   PKG +LYGPPGTG
Sbjct: 61  WWTGHPDPGN----------QGIR*A------AIDSSRVLRRDGNQAPKGVILYGPPGTG 192

Query: 180 KTLLARAVASQLDCNFLKVVSSSIVDKYIGESARLIREMFNYARDHQPCIIFMDEIDAIG 239
           KTLLA+AVA+Q    FL+VV S ++ KY+G+  +L+RE+F  A +H P I+F+DEIDA+G
Sbjct: 193 KTLLAKAVANQTSATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPSIVFIDEIDAVG 372

Query: 240 GRRFSEGTSADREIQRTLMELLNQMDGFDTLHRVKMIMATNRPDTLDPALLRPGRLDRKI 299
            +R+   +  +REIQRT++ELLNQ+DGFD+   VK+IMATNR +TLDPAL+RPGR+DRKI
Sbjct: 373 TKRYESNSGGEREIQRTMLELLNQLDGFDSRGDVKVIMATNRIETLDPALIRPGRIDRKI 552

Query: 300 HIDLPNEQARLDILKIHAGPITKHGEIDYEAIVKLSDGFNGADLRNVCTEAGMFAIRADH 359
              LP+E+ +  I  IH   +T  G+++ +  V   D  +GAD++ +CTEAG+ A+R   
Sbjct: 553 EFPLPDEKTKRRIFTIHTSRMTLAGDVNIDDYVMSKDDLSGADIKAICTEAGLLALRERR 732

Query: 360 DFVVQEDFMKAVRKV 374
             V  EDF KA   V
Sbjct: 733 MKVRNEDFAKAKENV 777

 Score = 47.0 bits (110), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 18/34 (52%), Positives = 29/34 (85%)
 Frame = +2

Query: 131 SYSEIGGLSEQIRELREVIELPLTNPELFQRVGI 164
           +Y++IGGL  QI+E++E +ELPLT+PE ++ +GI
Sbjct: 47  TYADIGGLDTQIQEIKESVELPLTHPEYYEEMGI 148
>02582
          Length = 1101

 Score =  173 bits (439), Expect = 9e-44,   Method: Compositional matrix adjust.
 Identities = 112/326 (34%), Positives = 171/326 (52%), Gaps = 39/326 (11%)
 Frame = +3

Query: 96  TRVALDMTTLTIMRYLPREVDPLVYNMSHEDPGNVSYSEIGGLSEQIRELREVIELPLTN 155
           TR  ++   LT    + R VD +V      D  +V +++IGGL     ++R+ +E PL  
Sbjct: 48  TRADMEAALLTFKPSMQRGVDCIV------DARSVPWTDIGGLDLVKLQIRQAVEWPLLY 209

Query: 156 PELFQRVGIIPPKGCLLYGPPGTGKTLLARAVASQLDCNFLKVVSSSIVDKYIGESARLI 215
           P+ FQ +G+   KG LLYGPPG GKT LA+A A+     FL +  + +   Y+G++ + I
Sbjct: 210 PDTFQALGLPLTKGVLLYGPPGCGKTTLAQAAATACHVTFLSLSCAQLYSPYVGDAEKKI 389

Query: 216 REMFNYARDHQPCIIFMDEIDAIGGRRFSEGTSADREIQRTLMELLNQMDGFDT------ 269
            E F  AR   P I+F+DE+DAI G+R S+ +      +R L  LLN+MDG         
Sbjct: 390 SETFQKARALAPSILFLDEMDAIVGKR-SDSSLGSGVSERVLSALLNEMDGIGVRLDDKS 566

Query: 270 ------------------LHRVK--------MIMATNRPDTLDPALLRPGRLDRKIHIDL 303
                              H VK        ++ ATNRPD LDPALLRPGR+DR I++  
Sbjct: 567 DSREMEIEGSSDHTPQVRQHAVKEAHDRHVLVVAATNRPDMLDPALLRPGRMDRLIYVPP 746

Query: 304 PNEQARLDILKIHAGPITKHGEIDYEAIVKLSDGFNGADLRNVCTEAGMFAIR--ADHDF 361
           P+ Q RL    IH   +    ++D + +  L+ G+ GAD++ +C E G+ A++     + 
Sbjct: 747 PDVQGRLQSFTIHTRKMPLGKDVDVKQLADLTAGYTGADIKTLCNEVGLLALKESMSAEC 926

Query: 362 VVQEDFMKAVRK-----VADSKKLES 382
           V Q+ F+ A++       ADS ++E+
Sbjct: 927 VNQDHFLNAIKTRKPSLSADSSEVET 1004
>03022
          Length = 2255

 Score =  157 bits (396), Expect = 8e-39,   Method: Compositional matrix adjust.
 Identities = 84/231 (36%), Positives = 138/231 (59%), Gaps = 3/231 (1%)
 Frame = +2

Query: 129  NVSYSEIGGLSEQIRELREVIELPLTNPELFQRVGIIPPKGCLLYGPPGTGKTLLARAVA 188
              ++ ++G LS    +L++ I   + +PE+    G+    G +L GPPG GKTL+A+A+A
Sbjct: 1415 TTTWEDVGALSNVRAQLKDSILCRIHDPEVSSAFGLPTNSGIILVGPPGCGKTLVAKAMA 1594

Query: 189  SQLDCNFLKVVSSSIVDKYIGESARLIREMFNYARDHQPCIIFMDEIDAI-GGRRFSEGT 247
            ++   NF+ +    ++DKY+GES R +RE F+ A+   PC+IF DE+D +   R+ ++G+
Sbjct: 1595 NEAGLNFIYIKGPELLDKYVGESERNLREKFDKAQACAPCLIFFDEMDTLCSNRQNNDGS 1774

Query: 248  SADREIQRTLMELLNQMDGFDTLHRVKMIMATNRPDTLDPALLRPGRLDRKIHIDLPNEQ 307
            +  + +   L+ L   MDG     +V ++ ATN  + +DPAL RPGR DRKI I LP+  
Sbjct: 1775 NVGKSVTNQLLAL---MDGCGERSQVYVMGATNIIENVDPALQRPGRFDRKIFIGLPDTD 1945

Query: 308  ARLDILK--IHAGPITKHGEIDYEAIVKLSDGFNGADLRNVCTEAGMFAIR 356
             RLDIL+     G   K    D + + + ++GF+GADL+++  EA   A++
Sbjct: 1946 GRLDILRALTKGGSQRKLESCDMQQLAQDTEGFSGADLKHLVNEASTIALK 2098

 Score = 58.5 bits (140), Expect(2) = 6e-12,   Method: Compositional matrix adjust.
 Identities = 33/117 (28%), Positives = 61/117 (52%), Gaps = 3/117 (2%)
 Frame = +1

Query: 129 NVSYSEIGGLSEQIRELREVIELPLTNPELFQRVGIIPPKGC---LLYGPPGTGKTLLAR 185
             +  + GG ++ + EL    E  L + +  Q       K C   LLYGP G+GK  LA 
Sbjct: 517 TATLDDFGGSNKLLAELDSDFEEILYS-DYCQYASACDQKACRRYLLYGPRGSGKRFLAE 693

Query: 186 AVASQLDCNFLKVVSSSIVDKYIGESARLIREMFNYARDHQPCIIFMDEIDAIGGRR 242
            +A QL    LK   ++++    G+S + +R++F+ A    PC++++++I+ +  R+
Sbjct: 694 CIAGQLKLPLLKPKINTLISGVSGDSEQRVRDLFDQAVSQAPCVLYLEDIECLAPRQ 864

 Score = 29.6 bits (65), Expect(2) = 6e-12,   Method: Compositional matrix adjust.
 Identities = 24/101 (23%), Positives = 44/101 (43%)
 Frame = +2

Query: 273  VKMIMATNRPDTLDPALLRPGRLDRKIHIDLPNEQARLDILKIHAGPITKHGEIDYEAIV 332
            V ++  T+R + +   L  PGR   K  + +P+E +R  +L+      T    +  + + 
Sbjct: 956  VVVVATTSRIEAVHRDLRIPGRFMEKA-LGMPDEGSREGLLQRLCSRYTLSPHLKLKTLA 1132

Query: 333  KLSDGFNGADLRNVCTEAGMFAIRADHDFVVQEDFMKAVRK 373
            +L+ GF   DLR +   A   A R   +    E    + R+
Sbjct: 1133 RLTPGFVAGDLRALVHGAFSTAFRRVRNLYRTESAESSTRR 1255
>12235
          Length = 1749

 Score =  138 bits (348), Expect = 3e-33,   Method: Compositional matrix adjust.
 Identities = 73/182 (40%), Positives = 109/182 (59%), Gaps = 2/182 (1%)
 Frame = +1

Query: 195 FLKVVSSSIVDKYIGESARLIREMFNYARDHQPCIIFMDEIDAIGGRRFSEGTSADREIQ 254
           F+ V  S  ++ ++G     +R+MF  AR + PCI+F+DEIDA+G +R         E +
Sbjct: 16  FITVSGSEFLEMFVGVGPSRVRDMFATARKNAPCILFVDEIDAVGRKRSGRNFGGQSEQE 195

Query: 255 RTLMELLNQMDGFDTLHRVKMIMATNRPDTLDPALLRPGRLDRKIHIDLPNEQARLDILK 314
            TL +LL +MDGF+T   V ++ ATNR D LD ALLRPGR DR+I + LP+ + R  I K
Sbjct: 196 NTLNQLLVEMDGFNTQTGVVVLAATNRVDILDAALLRPGRFDRQIFVPLPDIKXRASIFK 375

Query: 315 IHAGPI-TKHGEIDY-EAIVKLSDGFNGADLRNVCTEAGMFAIRADHDFVVQEDFMKAVR 372
           +H  P+ T+  + D    +  L+ GF+GAD+ NVC EA + A R  +  +    F +A+ 
Sbjct: 376 VHLDPLKTEVNKNDLARKMAALTPGFSGADIANVCNEAALIAARDLNTSIHMTHFEQAIE 555

Query: 373 KV 374
           +V
Sbjct: 556 RV 561
>00810
          Length = 1431

 Score =  129 bits (323), Expect = 2e-30,   Method: Compositional matrix adjust.
 Identities = 83/231 (35%), Positives = 128/231 (55%), Gaps = 3/231 (1%)
 Frame = -3

Query: 138  LSEQIRELREVIELPLTNPELFQRVGII-PPKGCLLYGPPGTGKTLLARAVASQLDCNFL 196
            L + I++++E + LP    +LF+   ++ PPKG LL+GPPG GKT++A+A A      F+
Sbjct: 1429 LEDVIQDVKETVILPFKRADLFRHSSLLQPPKGVLLHGPPGCGKTMIAKATAKAAGARFI 1250

Query: 197  KVVSSSIVDKYIGESARLIREMFNYARDHQPCIIFMDEIDAIGGRRFSEGTSADREIQRT 256
             +  SS+VDK+ GES +    +F+ A   QP IIF+DEID+    R S    A   I+  
Sbjct: 1249 NLQVSSLVDKWYGESQKRAEAVFSLAIKLQPTIIFIDEIDSFLRSRTSTDHEATAMIKTQ 1070

Query: 257  LMELLNQMDGF--DTLHRVKMIMATNRPDTLDPALLRPGRLDRKIHIDLPNEQARLDILK 314
             M      DG   D   RV ++ ATNRP  +D A+LR  R+    HI LP    R  I  
Sbjct: 1069 FMSF---WDGLMTDPDCRVMVMGATNRPQDVDAAILR--RMPSMFHIGLPGPAQRRSIFN 905

Query: 315  IHAGPITKHGEIDYEAIVKLSDGFNGADLRNVCTEAGMFAIRADHDFVVQE 365
            +      +   ++Y+ + +++DGF+G+D+R VC  A   A+   H+F+ +E
Sbjct: 904  LILSK-ERIDALNYDELAEMTDGFSGSDIREVCRAA---AVATVHEFIQEE 764
>20270
          Length = 542

 Score =  108 bits (271), Expect = 3e-24,   Method: Compositional matrix adjust.
 Identities = 57/128 (44%), Positives = 83/128 (64%), Gaps = 2/128 (1%)
 Frame = -3

Query: 166 PPKGCLLYGPPGTGKTLLARAVASQLD-CNFLKVVSSSIVDKYIGESARLIREMFNYARD 224
           P +G LLYGPPGTGK+ LA+AVA++ +   F  V SS +V K++GES +L++ +F  AR+
Sbjct: 384 PWRGILLYGPPGTGKSYLAKAVATEANNSTFFSVSSSDLVSKWLGESEKLVKTLFQLARE 205

Query: 225 HQPCIIFMDEIDAIGGRRFSEGTSADREIQRTLMELLNQMDGFDTLHRVKMIM-ATNRPD 283
           +QP IIF+DE+DA+ G R    + + R I+    E L QM G    +   +++ ATN P 
Sbjct: 204 NQPSIIFIDEVDALCGSRSENESESARRIK---TEFLVQMQGVGNDNTGVLVLGATNIPW 34

Query: 284 TLDPALLR 291
           TLD A+ R
Sbjct: 33  TLDSAIRR 10
>38672
          Length = 730

 Score = 82.4 bits (202), Expect(2) = 7e-22,   Method: Compositional matrix adjust.
 Identities = 42/113 (37%), Positives = 66/113 (58%)
 Frame = -3

Query: 254 QRTLMELLNQMDGFDTLHRVKMIMATNRPDTLDPALLRPGRLDRKIHIDLPNEQARLDIL 313
           +R + +LL  MDG      V ++ ATNRP+++D AL R GR DR++ I +P+   RL+IL
Sbjct: 587 RRIVSQLLTLMDGLKQRSHVIVMAATNRPNSVDAALRRFGRFDREVDIGIPDATGRLEIL 408

Query: 314 KIHAGPITKHGEIDYEAIVKLSDGFNGADLRNVCTEAGMFAIRADHDFVVQED 366
           +IH   +    ++D E +   + G  GAD+  +C+EA +  IR   D +  ED
Sbjct: 407 RIHTKNMKLADDVDLEQVASETHGHVGADVAALCSEAALQQIREKMDLIDLED 249

 Score = 39.3 bits (90), Expect(2) = 7e-22,   Method: Compositional matrix adjust.
 Identities = 18/40 (45%), Positives = 25/40 (62%)
 Frame = -1

Query: 203 IVDKYIGESARLIREMFNYARDHQPCIIFMDEIDAIGGRR 242
           I+ K  GES   +R+ F  A  + P IIF+DE+DAI  +R
Sbjct: 730 IMSKLAGESESNLRKAFEEAEKNAPAIIFIDELDAIAPKR 611

 Score = 46.6 bits (109), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 18/44 (40%), Positives = 30/44 (68%)
 Frame = -3

Query: 129 NVSYSEIGGLSEQIRELREVIELPLTNPELFQRVGIIPPKGCLL 172
           NVS+ ++GGL    +EL+E+++ P+ +PE F + G+ P KG L 
Sbjct: 134 NVSWEDVGGLENVKKELQELVQYPVEHPEKFLKFGMTPSKGVLF 3
>25671
          Length = 441

 Score = 82.0 bits (201), Expect = 4e-16,   Method: Compositional matrix adjust.
 Identities = 53/154 (34%), Positives = 79/154 (51%), Gaps = 6/154 (3%)
 Frame = +2

Query: 178 TGKTLLARAVASQLDCNFLKVVSSSIVDKYIGESARLIREMFNYARDHQPCIIFMDEIDA 237
           TGKT+LA+AVA++    F  V +SS+ +KY GES +L+R +F  A  + P  IF+DEID+
Sbjct: 2   TGKTMLAKAVATECGTTFFNVSTSSLANKYRGESEKLVRLLFEMAHFYAPSTIFIDEIDS 181

Query: 238 IGGRRFSEGTSADREIQRTL-MELLNQMDGF-----DTLHRVKMIMATNRPDTLDPALLR 291
           I  +R   G+ ++ E  R +  ELL QMDG      D    V ++ ATN P         
Sbjct: 182 ICSKR---GSDSEHEASRRVKSELLVQMDGVGVTNDDPSKAVMVLAATNFP--------- 325

Query: 292 PGRLDRKIHIDLPNEQARLDILKIHAGPITKHGE 325
              L  +  ++ P  +  L    +  GP    G+
Sbjct: 326 ---LGHRRGLEAPPGETHLHPTALSGGPACAAGD 418
>26408
          Length = 463

 Score = 74.3 bits (181), Expect = 7e-14,   Method: Compositional matrix adjust.
 Identities = 57/157 (36%), Positives = 79/157 (50%), Gaps = 12/157 (7%)
 Frame = +1

Query: 46  DLKALQSVGQIVGEVLKQLTEEKFIVKATNGPRYVVGCRRQLDKSKLKPGTRVALDMTTL 105
           +L+ LQ  G  VGEV+K + ++K +VK     ++VV      D  +     R    +   
Sbjct: 1   ELQLLQEQGSYVGEVVKPMDKKKVLVKVHPEGKFVV------DFGQEY*YKRCYAQLPCR 162

Query: 106 TIMRYLPREVDPLVYNMSHEDPGNVSYSEIGGLSEQI------------RELREVIELPL 153
           T  R L    D        +  G+ S+ + G  S +             + ++EVIELP+
Sbjct: 163 TAQRKLHTTQD------LAKQSGSASFVDDGRKSARFNIRNGWWLG*ANQRIKEVIELPV 324

Query: 154 TNPELFQRVGIIPPKGCLLYGPPGTGKTLLARAVASQ 190
            +PELF  +GI  PKG LLYGPPGTGKTLLARAVA  
Sbjct: 325 KHPELFDALGIAQPKGVLLYGPPGTGKTLLARAVAHH 435

 Score = 49.3 bits (116), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 36/139 (25%), Positives = 62/139 (44%)
 Frame = +2

Query: 60  VLKQLTEEKFIVKATNGPRYVVGCRRQLDKSKLKPGTRVALDMTTLTIMRYLPREVDPLV 119
           +L Q T  + ++K       +    + +D + + P  RVAL   + T+ + LP +VDPLV
Sbjct: 44  LLSQWTRRRCLLKFIRKASSLSILDKNIDINDVTPNCRVALRNESYTLHKILPNKVDPLV 223

Query: 120 YNMSHEDPGNVSYSEIGGLSEQIRELREVIELPLTNPELFQRVGIIPPKGCLLYGPPGTG 179
             M  E   + +Y  +GGL +QI+E R     P + P       ++  +       P   
Sbjct: 224 SLMMVEKVPDSTYEMVGGLDKQIKESRR*SNCPSSIPNCSMPWALLSQRVYCCTVRPVLA 403

Query: 180 KTLLARAVASQLDCNFLKV 198
           K  L   +    +C F++V
Sbjct: 404 KRCLPVRLPITPECTFIRV 460
>02194
          Length = 1891

 Score = 65.9 bits (159), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 52/152 (34%), Positives = 76/152 (50%), Gaps = 3/152 (1%)
 Frame = -1

Query: 154  TNPELFQRVGIIPPKGCLLYGPPGTGKTLLARAVASQLDCNFLKVVSSSIVDKYIGESAR 213
            T P  +   GI   +G LLYGPPG GK+    A+A  LD N   +   ++ +K  G S  
Sbjct: 1537 TAPRWYMDRGIPYRRGYLLYGPPGCGKSSYIMALAGALDYN---ICVLNLSEK--GLSDD 1373

Query: 214  LIREMFNYARDHQPCIIFMDEIDAIGGRR--FSEGTSADREIQR-TLMELLNQMDGFDTL 270
             +  +   A +    II ++++DA    R    E  +  + + R T   LLN +DG  + 
Sbjct: 1372 RLNHLLTVAPEQS--IILLEDVDAAFLSRDLSKENPAMYQGMGRLTFSGLLNALDGVASA 1199

Query: 271  HRVKMIMATNRPDTLDPALLRPGRLDRKIHID 302
                + M TN  D LDPAL+RPGR+D K  +D
Sbjct: 1198 EARIVFMTTNYLDRLDPALIRPGRVDMKELVD 1103
>17843
          Length = 772

 Score = 54.7 bits (130), Expect = 6e-08,   Method: Compositional matrix adjust.
 Identities = 43/154 (27%), Positives = 71/154 (46%), Gaps = 16/154 (10%)
 Frame = +1

Query: 171 LLYGPPGTGKTLLARAVASQL--------DC-NFLKVVSSSIVDKYIGESARLIREMFNY 221
           LL+GPPGTGKT L +A+A +L         C   +++ S S+  K+  ES +L+ +MF  
Sbjct: 196 LLHGPPGTGKTTLCKALAHKLCIRLSHRFSCGQLVEINSHSLFSKWFSESGKLVTKMFQR 375

Query: 222 ARDHQP-----CIIFMDEIDAIGGRRFS--EGTSADREIQRTLMELLNQMDGFDTLHRVK 274
             D+         + +DE++++   R S   G      I R +  +L Q+D         
Sbjct: 376 LHDYMVDPELLVCVLIDEVESLTAARKSCLNGNEPSDAI-RVVNAVLTQIDQLKKFANCL 552

Query: 275 MIMATNRPDTLDPALLRPGRLDRKIHIDLPNEQA 308
           ++  +N    +D A +   R D K +I  P   A
Sbjct: 553 ILTTSNITGAIDLAFV--DRADIKQYIGPPTPPA 648
>06766
          Length = 976

 Score = 50.8 bits (120), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 28/65 (43%), Positives = 41/65 (63%), Gaps = 2/65 (3%)
 Frame = +2

Query: 294 RLDRKIHIDLPNEQARLDILK--IHAGPITKHGEIDYEAIVKLSDGFNGADLRNVCTEAG 351
           RLD+ I+I LP++++R  ILK  +   P+ K  E+D   I K++ GF+GADL  +C  A 
Sbjct: 2   RLDQLIYIPLPDDKSREAILKANLRKSPLAK--EVDLTYIAKVTQGFSGADLTEICQRAC 175

Query: 352 MFAIR 356
             AIR
Sbjct: 176 KLAIR 190
>26887
          Length = 410

 Score = 44.7 bits (104), Expect = 7e-05,   Method: Compositional matrix adjust.
 Identities = 19/38 (50%), Positives = 28/38 (73%)
 Frame = -3

Query: 242 RFSEGTSADREIQRTLMELLNQMDGFDTLHRVKMIMAT 279
           R+   +  +REIQRT++ELLNQ+DGFD+   VK+ + T
Sbjct: 168 RYESNSGGEREIQRTMLELLNQLDGFDSRGDVKVHLXT 55
>14413
          Length = 826

 Score = 42.0 bits (97), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 36/149 (24%), Positives = 69/149 (46%), Gaps = 14/149 (9%)
 Frame = +2

Query: 180 KTLLARAVASQLD---------CNFLKVVSSSIVDKYIGESARLIREMFN----YARDHQ 226
           KT L +A+A +L           + +++ S S+  K+  ES +L+  +F      A D  
Sbjct: 2   KTSLCKALAEKLAIRTQNSFAYTHLVEINSHSLFSKWFSESGKLVARLFGKIGELATDKN 181

Query: 227 PCI-IFMDEIDAIGGRRFSEGTSADREIQRTLMELLNQMDGFDTLHRVKMIMATNRPDTL 285
             + + +DE++++   R +  ++  R+  R +  +L Q+D       V ++  +N   ++
Sbjct: 182 NLVCVLIDEVESLAYARSAMSSNEPRDAMRVVNAVLTQLDEIKACPNVLILATSNLAQSI 361

Query: 286 DPALLRPGRLDRKIHIDLPNEQARLDILK 314
           D A L   R D +  I LP+  A   I K
Sbjct: 362 DLAFL--DRADIRQFIGLPDPLAISSIYK 442
>27434
          Length = 472

 Score = 37.0 bits (84), Expect = 0.012,   Method: Compositional matrix adjust.
 Identities = 22/76 (28%), Positives = 35/76 (46%), Gaps = 9/76 (11%)
 Frame = +2

Query: 172 LYGPPGTGKTLLARAVASQLDCNFLKVVSSSIVDK---------YIGESARLIREMFNYA 222
             GPPG GKT + R++A+ L   F ++    + D+         YIG     I +    A
Sbjct: 176 FVGPPGVGKTSIGRSIATTLGREFHRIALGGVCDQSDIRGHRRTYIGSMPGRIIQGLKSA 355

Query: 223 RDHQPCIIFMDEIDAI 238
             + P +  +DEID +
Sbjct: 356 GTNNP-VFPLDEIDKL 400
>37695
          Length = 156

 Score = 35.4 bits (80), Expect = 0.037,   Method: Composition-based stats.
 Identities = 15/25 (60%), Positives = 18/25 (72%)
 Frame = +3

Query: 347 CTEAGMFAIRADHDFVVQEDFMKAV 371
           CTEAGMFAIRA      ++DF+ AV
Sbjct: 9   CTEAGMFAIRARRKMATEKDFLDAV 83
>01279
          Length = 2183

 Score = 35.0 bits (79), Expect = 0.047,   Method: Compositional matrix adjust.
 Identities = 47/170 (27%), Positives = 74/170 (43%), Gaps = 7/170 (4%)
 Frame = -3

Query: 168  KGCLLYGPPGTGKTLLARAVASQLDCN--FLKVVSSSIVDKYIGESARLIREMFNYARDH 225
            +  LL GPPGTGKT +A A+A +L     F  +V S +    I ++  L   M N+ R  
Sbjct: 1914 RAVLLAGPPGTGKTAIALAIAQELGNKVPFCPMVGSEVYSSEIKKTEVL---MENFRR-- 1750

Query: 226  QPCIIFMDEIDAIGGRRFSEGTSADREI-QRTLMELLNQMDGFD-TLHRVKMIMATNRPD 283
                       AIG R        + E+ + T +E  N M G+  T+  V + + T +  
Sbjct: 1749 -----------AIGLRIKETKEVYEGEVTELTPVETENPMGGYGKTVSHVVIGLKTAKGT 1603

Query: 284  TLDPALLRPGRLDRKIHIDLPNEQARL-DILKIHA--GPITKHGEIDYEA 330
                   +  +LD  I+  L  E+  + D++ I A  G + + G  D  A
Sbjct: 1602 -------KQLKLDPSIYESLQKEKVEVGDVIYIEANSGAVKRQGRSDSYA 1474
>19561
          Length = 474

 Score = 34.7 bits (78), Expect = 0.062,   Method: Compositional matrix adjust.
 Identities = 26/75 (34%), Positives = 37/75 (49%), Gaps = 5/75 (6%)
 Frame = -1

Query: 168 KGCLLYGPPGTGKTLLARAVASQLDCNFLKVVSS-----SIVDKYIGESARLIREMFNYA 222
           K  LL GPPG GKT LA  VA     N +++ +S      +    I E+A  +R +    
Sbjct: 378 KVALLCGPPGLGKTTLAHIVAKHAGYNVVEMNASDDRSVEVFSNKI-EAATQMRAVMGA- 205

Query: 223 RDHQPCIIFMDEIDA 237
            D +P  + +DEID 
Sbjct: 204 -DPRPNCLIIDEIDG 163
>24645
          Length = 1071

 Score = 28.1 bits (61), Expect = 7.0,   Method: Compositional matrix adjust.
 Identities = 12/30 (40%), Positives = 19/30 (63%)
 Frame = -2

Query: 348 TEAGMFAIRADHDFVVQEDFMKAVRKVADS 377
           T+  +FA +A HD V  ED  + +R +AD+
Sbjct: 392 TKLLLFAAQASHDLVPPEDMEQVLRTIADN 303
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6753320|ref|NP_033966.1| chaperonin containing Tcp1,
subunit 3 (gamma) [Mus musculus]
         (545 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

29631                                                                 284   e-175
01159                                                                 290   9e-79
05356                                                                 113   5e-48
09900                                                                 165   5e-41
29864                                                                 143   2e-34
17249                                                                 141   6e-34
06409                                                                 140   1e-33
12796                                                                 132   3e-31
33770                                                                 110   1e-24
02673                                                                  55   5e-08
30661                                                                  55   6e-08
12205                                                                  32   0.60 
12323                                                                  32   0.74 
12624                                                                  29   5.5  
00104                                                                  28   9.7  
>29631
          Length = 1257

 Score =  284 bits (727), Expect(3) = e-175,   Method: Compositional matrix adjust.
 Identities = 129/199 (64%), Positives = 169/199 (84%)
 Frame = +1

Query: 158 SSITTKVISRWSSLACNIALDAVKTVQFEENGRKEIDIKKYARVEKIPGGIIEDSCVLRG 217
           S + TK IS+W  LAC IALDA  TV  EENGRKEIDIK+YA+VEKIPGG +E+S VL+G
Sbjct: 460 SCLGTKFISKWMDLACQIALDATTTVFMEENGRKEIDIKRYAKVEKIPGGTMEESEVLKG 639

Query: 218 VMINKDVTHPRMRRYIKNPRIVLLDSSLEYKKGESQTDIEITREEDFTRILQMEEEYIHQ 277
           + +NKDV H +M+R I+NPRI+LLD +LEYKKGES T+IEI++EEDF +ILQ+EEEYI +
Sbjct: 640 IXVNKDVVHXKMKRRIENPRIMLLDCNLEYKKGESATNIEISKEEDFAKILQLEEEYIRK 819

Query: 278 LCEDIIQLKPDVVITEKGISDLAQHYLMRANVTAIRRVRKTDNNRIARACGARIVSRPEE 337
           +C++II LKPD+VITEKG+SDLAQH+L++A ++ +RRVRKTDNNRIARACGA I +R +E
Sbjct: 820 MCDEIIALKPDLVITEKGVSDLAQHFLLKAGISVLRRVRKTDNNRIARACGATIANRTDE 999

Query: 338 LREDDVGTGAGLLEIKKIG 356
           L+E+D+G+G GLL+  ++ 
Sbjct: 1000LKEEDMGSGCGLLKCARLA 1056

 Score =  243 bits (620), Expect(3) = e-175,   Method: Compositional matrix adjust.
 Identities = 115/151 (76%), Positives = 136/151 (90%), Gaps = 1/151 (0%)
 Frame = +3

Query: 7   VLVLSQNTKRESGRKVQSGNINAAKTIADIIRTCLGPKSMMKMLLDPMGGIVMTNDGNAI 66
           ++VL+QNT+RESGRKVQ GNI A KTIAD+IRTCLGPKSM+KML+DPMGGIVMTNDGNAI
Sbjct: 3   IIVLNQNTRRESGRKVQLGNIAAGKTIADVIRTCLGPKSMLKMLMDPMGGIVMTNDGNAI 182

Query: 67  LREIQVQHPAAKSMIEISRTQDEEVGDGTTSVIILAGEMLSVAEHFLEQQMHPTVVISAY 126
           LREI VQHPAAKSMIE++RTQDEE GDGT SVIILAGE+LSVAE FLEQQMHPTV+I+AY
Sbjct: 183 LREINVQHPAAKSMIEVARTQDEETGDGTKSVIILAGEVLSVAEQFLEQQMHPTVIIAAY 362

Query: 127 RMALDDMISTLK-KISTPVDVNNREMMLSII 156
           R AL+D +  L+ KI TP+D+++R  ML+I+
Sbjct: 363 RQALEDTLEVLRTKICTPIDISDRNQMLNIV 455

 Score =  128 bits (322), Expect(3) = e-175,   Method: Compositional matrix adjust.
 Identities = 57/74 (77%), Positives = 66/74 (89%)
 Frame = +3

Query: 350  LEIKKIGDEYFTFITDCKDPKACTILLRGASKEILSEVERNLQDAMQVCRNVLLDPQLVP 409
            LE++KIGD+YFTF+ DCK PKACTILLRGASK+IL+EVERNLQDAM V RNV++DP L P
Sbjct: 1035 LEVRKIGDDYFTFLVDCKSPKACTILLRGASKDILAEVERNLQDAMNVARNVMIDPHLCP 1214

Query: 410  GGGASEMAVAHALT 423
            GGGASEMA+A AL 
Sbjct: 1215 GGGASEMALAQALN 1256
>01159
          Length = 2613

 Score =  290 bits (742), Expect = 9e-79,   Method: Compositional matrix adjust.
 Identities = 174/524 (33%), Positives = 305/524 (58%), Gaps = 6/524 (1%)
 Frame = +3

Query: 5   RPVLVLSQNTK--RESGRKVQSGNINAAKTIADIIRTCLGPKSMMKMLLDPMGGIVMTND 62
           RP ++L    K  R +G +    +I AAK++A I++T LGPK + KM++   G + +TND
Sbjct: 132 RPFIILRDQDKKSRLTGIEAHKSHILAAKSVASILKTSLGPKGLDKMMVSGDGDVTVTND 311

Query: 63  GNAILREIQVQHPAAKSMIEISRTQDEEVGDGTTSVIILAGEMLSVAEHFLEQQMHPTVV 122
           G  IL  + V H  AK M+++S++QD+E+GDGTT V++LAG +L  AE  L++ +HP  +
Sbjct: 312 GATILDMMDVDHQIAKLMVQLSKSQDDEIGDGTTGVVVLAGALLEQAEKLLDRGIHPIRI 491

Query: 123 ISAYRMALDDMISTLKKIS--TPVDVNNREMMLSIINSSITTKVISRWSSLACNIALDAV 180
              Y +A    + TL KIS    VD+ N E ++ +  +++ +K+++R       IA+DA+
Sbjct: 492 ADGYEIAAKCAVETLDKISDNYEVDLKNAEPLIKLAMTTLGSKIVNRCHRQMAKIAVDAI 671

Query: 181 KTVQFEENGRKEIDIKKYARVEKIPGGIIEDSCVLRGVMINKDVTHPRMRRYIKNPRIVL 240
            +V   +  RK++D  +  +VE   GG +ED+ +++GV+++KD++HP+M + +K+ +I +
Sbjct: 672 MSVA--DLKRKDVDF-ELIKVEGKVGGKLEDTMLVKGVVVDKDMSHPQMPKVVKDAKIAI 842

Query: 241 LDSSLEYKKGESQTDIEITREEDFTRILQMEEEYIHQLCEDIIQLKPDVVITEKGISDLA 300
           L    E  K +++  ++IT  ED+ ++ + E      + + +     ++VI + G  D A
Sbjct: 843 LTCPFEPPKPKTKHKLDITSVEDYKKLREYELNKFESMVQSVKDKGANLVICQWGFDDEA 1022

Query: 301 QHYLMRANVTAIRRVRKTDNNRIARACGARIVSRPEELREDDVGTGAGLLEIKKIG--DE 358
            H L++  + A+R V   +   IA A G RIV R EEL  + +G  AG++     G   +
Sbjct: 1023NHLLLQRELPAVRWVGGPEIELIAIATGGRIVPRFEELTTEKLGK-AGIVRELTFGTTKD 1199

Query: 359 YFTFITDCKDPKACTILLRGASKEILSEVERNLQDAMQVCRNVLLDPQLVPGGGASEMAV 418
               I +C + +A TI +RG +K I+ E +R+L DA+ V RN++ D ++V GGGA E+A 
Sbjct: 1200RMLVIEECLNTRAVTIFIRGGNKMIVEEAKRSLHDALCVIRNLVRDNRVVYGGGAPEIAA 1379

Query: 419 AHALTEKSKAMTGVEQWPYRAVAQALEVIPRTLIQNCGASTIRLLTSLRAKHTQESCETW 478
           + A+ E +  ++ +EQ+  R+ ++ALE +P  L +N G + I+ L  ++++  +E     
Sbjct: 1380SVAVAEAADKISTLEQYAVRSFSEALEAVPLALAENSGLAPIQTLAEVKSRQVKEKNPRL 1559

Query: 479 GVNGETGTLVDMKELGIWEPLAVKLQTYKTAVETAVLLLRIDDI 522
           G++       DMKE  + E L  K Q    A +   ++L+IDDI
Sbjct: 1560GIDCLLKGTNDMKEQNVIETLTAKKQQILLATQLVRMILKIDDI 1691
>05356
          Length = 2339

 Score =  113 bits (282), Expect(2) = 5e-48,   Method: Compositional matrix adjust.
 Identities = 70/237 (29%), Positives = 125/237 (52%), Gaps = 2/237 (0%)
 Frame = +1

Query: 296  ISDLAQHYLMRANVTAIRRVRKTDNNRIARACGARIVSRPEELREDDVGTGAGLLEIKKI 355
            + DLAQHY  +  V  IR + K D  R+ ++  A  + +    R ++ G    L+ + +I
Sbjct: 1078 VGDLAQHYCNKYKVMVIRLLSKWDLRRLCKSICATALPKVTTPRNEECGY-CDLVYVDEI 1254

Query: 356  GDEYFTFITDCKDPKA-CTILLRGASKEILSEVERNLQDAMQVCRNVLLDPQLVPGGGAS 414
            G+         KD     T+++RG++  I+ ++ER L D +   + +  D +LVPG GA+
Sbjct: 1255 GETPVVIFQQNKDESPITTVIIRGSTDNIMDDIERALDDGVNTFKALTKDDRLVPGAGAT 1434

Query: 415  EMAVAHALTEKSKAMTGVEQWPYRAVAQALEVIPRTLIQNCGASTIRLLTSLRAKHTQES 474
            E+ +A  +T   +++ G+EQ+  +  A++LEVIPR L +N G     +L+ L A H QE 
Sbjct: 1435 EIELAKQITTYGESLPGLEQYAVKKFAESLEVIPRALAENTGMKATDILSKLYAAH-QEG 1611

Query: 475  CETWGVN-GETGTLVDMKELGIWEPLAVKLQTYKTAVETAVLLLRIDDIVSGHKKKG 530
             +  GV+  ++G+++D K+  + +    +    K A   A  +LR+D I+      G
Sbjct: 1612 QQNAGVDIDDSGSVLDAKQANLTDLYLNRYWGLKFAAAAACTVLRVDQIIMAKPAGG 1782

 Score = 97.1 bits (240), Expect(2) = 5e-48,   Method: Compositional matrix adjust.
 Identities = 73/268 (27%), Positives = 132/268 (49%), Gaps = 2/268 (0%)
 Frame = +2

Query: 26  NINAAKTIADIIRTCLGPKSMMKMLLDPMGGIVMTNDGNAILREIQVQHPAAKSMIEISR 85
           NI A K +A   R+  GP    KM+++ +  + +TND   ILRE++VQHPAAK ++  + 
Sbjct: 284 NIEACKELAKTTRSAYGPHGQNKMVINHLEKLFVTNDAATILRELEVQHPAAKMLVLAAH 463

Query: 86  TQDEEVGDGTTSVIILAGEMLSVAEHFLEQQMHPTVVISAYRMALDDMISTLKK--ISTP 143
            Q++E GDGT  V++ AG +L  AE  L   +  T VI  Y +AL      L K  I   
Sbjct: 464 QQEQECGDGTNFVLVFAGALLENAEQLLRMGLSVTEVIEGYELALKKAHEILPKLVIGHV 643

Query: 144 VDVNNREMMLSIINSSITTKVISRWSSLACNIALDAVKTVQFEENGRKEIDIKKYARVEK 203
            ++ N+E + + I +S+ +K       LA ++  DA  +V         +D     RV K
Sbjct: 644 KNLRNKEEVKTAIRTSVMSKQYGNEDFLA-DLITDACVSV-LPAKISFSVD---NVRVCK 808

Query: 204 IPGGIIEDSCVLRGVMINKDVTHPRMRRYIKNPRIVLLDSSLEYKKGESQTDIEITREED 263
           I G  +  S  ++G++  + V     +  ++  ++ +    L+  + E++  + I   E+
Sbjct: 809 ILGCGLLQSSTIQGMVFKRQVEGEITK--VEKAKVAVFTCPLDSMQTETKGTVLIKNAEE 982

Query: 264 FTRILQMEEEYIHQLCEDIIQLKPDVVI 291
                + EE+ + +  + I +   +V++
Sbjct: 983 LMSFSKGEEDMMEEQIKGIKEAGVNVIV 1066
>09900
          Length = 1305

 Score =  165 bits (417), Expect = 5e-41,   Method: Compositional matrix adjust.
 Identities = 104/312 (33%), Positives = 157/312 (50%), Gaps = 1/312 (0%)
 Frame = +3

Query: 234 KNPRIVLLDSSLEYKKGESQTDIEITREEDFTRILQMEEEYIHQLCEDIIQLKPDVVITE 293
           + PRI LL+  LE K      ++ +   +++  I+  E + ++   + I Q    VV+++
Sbjct: 51  RTPRIALLNIELELKSERDNAEVRVDNVQEYQSIVDAEWKILYDKLDKIHQSGAKVVLSK 230

Query: 294 KGISDLAQHYLMRANVTAIRRVRKTDNNRIARACGARIVSRPEELREDDVGTGAGLLEIK 353
             I D+A  Y    ++    RV + D  R  +ACG  I +  + L  D +GT     EI+
Sbjct: 231 LPIGDVATQYFADRDMFCAGRVPEEDLRRTMKACGGSIQTTVQSLTPDVLGTCQLFDEIQ 410

Query: 354 KIGDEYFTFITDCKDPKACTILLRGASKEILSEVERNLQDAMQVCRNVLLDPQLVPGGGA 413
            IG E F     C   + CTI+LRG +++ + E ER+L DA+ + R  + +  +V GGGA
Sbjct: 411 -IGGERFNMFKGCTMARTCTIILRGGAEQFMEETERSLHDAIMIVRRAIKNDSVVAGGGA 587

Query: 414 SEMAVAHALTEKSKAMTGVEQWPYRAVAQALEVIPRTLIQNCGASTIRLLTSLRAKHTQE 473
            EM V++ L E S  + G EQ    A A+ALEVIPR L  N G     +L  LR KH Q 
Sbjct: 588 IEMEVSYHLREHSHTIAGKEQLLMSAYAKALEVIPRQLCDNAGFDATNILNKLRQKHAQG 767

Query: 474 SCETW-GVNGETGTLVDMKELGIWEPLAVKLQTYKTAVETAVLLLRIDDIVSGHKKKGDD 532
              TW GVN     + D  E  +WEP  VK+     A E   L+L +D+ +       + 
Sbjct: 768 G--TWYGVNILREDIADNFEDCVWEPAVVKINALTAASEATALILSVDETIK------NP 923

Query: 533 QNRQTGAPDAGQ 544
           ++ Q  AP AG+
Sbjct: 924 RSGQGDAPGAGR 959
>29864
          Length = 1026

 Score =  143 bits (360), Expect = 2e-34,   Method: Compositional matrix adjust.
 Identities = 82/265 (30%), Positives = 149/265 (56%), Gaps = 2/265 (0%)
 Frame = +1

Query: 13  NTKRESGRKVQS--GNINAAKTIADIIRTCLGPKSMMKMLLDPMGGIVMTNDGNAILREI 70
           N K E  R  Q+   NI AAK + D++R+ LGPK  MKML+   G I +T DGN +L E+
Sbjct: 130 NPKAEVARASQALAVNIAAAKGLQDVLRSNLGPKGTMKMLVSGAGDIKLTKDGNVLLHEM 309

Query: 71  QVQHPAAKSMIEISRTQDEEVGDGTTSVIILAGEMLSVAEHFLEQQMHPTVVISAYRMAL 130
           Q+QHP A  +  ++  QD+  GDGTTS +++ GE+L  A+ ++ + +HP ++   + +A 
Sbjct: 310 QIQHPTASLIARVATAQDDITGDGTTSNVLIIGELLKQADLYIAEGLHPRLITEGFELAR 489

Query: 131 DDMISTLKKISTPVDVNNREMMLSIINSSITTKVISRWSSLACNIALDAVKTVQFEENGR 190
           +  +  L+++    +V +RE ++ +  +S+ TKV +  + L     +DAV  +Q    G 
Sbjct: 490 NKALEVLEEVKVKREV-DRETLVQVARTSLRTKVHTELADLLTEHVVDAVLAIQXPGEG- 663

Query: 191 KEIDIKKYARVEKIPGGIIEDSCVLRGVMINKDVTHPRMRRYIKNPRIVLLDSSLEYKKG 250
             ID+     +E +      DS ++RG++++    HP M+++ K+  I+  + SLEY+K 
Sbjct: 664 --IDLHMVELME-MQHKTDLDSTLVRGLVMDHGARHPDMKKHTKDAFILTCNVSLEYEKT 834

Query: 251 ESQTDIEITREEDFTRILQMEEEYI 275
           E  +       ++  ++++ E  +I
Sbjct: 835 EVNSGFFYKTAQEREKLVEAERTFI 909
>17249
          Length = 909

 Score =  141 bits (356), Expect = 6e-34,   Method: Compositional matrix adjust.
 Identities = 70/111 (63%), Positives = 81/111 (72%), Gaps = 5/111 (4%)
 Frame = +3

Query: 440 VAQALEVIPRTLIQNCGASTIRLLTSLRAKHTQESCETWGVNGETGTLVDMKELGIWEPL 499
           +++ALEVI RTLIQNCGA+TIR LT+LRAKH Q    TWG++G TG +VDM E GIWEPL
Sbjct: 3   ISRALEVISRTLIQNCGANTIRTLTALRAKHAQGQKNTWGIDGNTGNIVDMAEFGIWEPL 182

Query: 500 AVKLQTYKTAVETAVLLLRIDDIVSGHKK-----KGDDQNRQTGAPDAGQE 545
           +VKLQ YKTA ETA+LLLRIDDIVSG KK      G  +     AP  G E
Sbjct: 183 SVKLQVYKTACETAILLLRIDDIVSGTKKMDAAMSGASKQEAPAAPPPGGE 335
>06409
          Length = 1533

 Score =  140 bits (353), Expect = 1e-33,   Method: Compositional matrix adjust.
 Identities = 87/298 (29%), Positives = 157/298 (52%), Gaps = 6/298 (2%)
 Frame = -3

Query: 233  IKNPRIVLLDSSLEYKKGESQTDIEITREEDFTRILQMEEEYIHQLCEDIIQLKPDVVIT 292
            ++  +I  +   +   K + +  + ++      R+L+ E  YI  + + I +   +V++ 
Sbjct: 1492 VEKAKIGFIQFCISPPKTDMENQVIVSDYTQMDRVLREERNYILDIVKKIKKAGCNVLLI 1313

Query: 293  EKGI-----SDLAQHYLMRANVTAIRRVRKTDNNRIARACGARIVSRPEELREDDVGTGA 347
            +K I     SDLA H+L +  +  ++ + + D   + +  G R V+  +    +++G+ A
Sbjct: 1312 QKSILRDAVSDLALHFLAKMKIMVVKDIEREDVEFVCKTLGCRPVASLDHFLPENLGS-A 1136

Query: 348  GLLEIKKIGDEYFTFITDCKDP-KACTILLRGASKEILSEVERNLQDAMQVCRNVLLDPQ 406
             L+E  + G       T   +P +  T+L+RG++K +L E +R+L DA+ V R ++    
Sbjct: 1135 DLIEEVQTGSSKIVKATGIANPGQTVTVLIRGSNKLVLEEADRSLHDALCVIRCLVKKKA 956

Query: 407  LVPGGGASEMAVAHALTEKSKAMTGVEQWPYRAVAQALEVIPRTLIQNCGASTIRLLTSL 466
            L+ GGGA E  ++  L   +  + G+EQ+ +RA A+ALEVIP TL +N G + I  +T L
Sbjct: 955  LIAGGGAPETEMSMRLAAYANTLAGMEQYCFRAFAEALEVIPFTLAENAGLNPISTVTXL 776

Query: 467  RAKHTQESCETWGVNGETGTLVDMKELGIWEPLAVKLQTYKTAVETAVLLLRIDDIVS 524
            R +H Q    T G+N   G + ++ E  + +PL V       A ET   +L+IDDIV+
Sbjct: 775  RTRHAQGE-RTAGINVRKGAITNILEENVLQPLLVSTSAITLASETVRSILKIDDIVN 605
>12796
          Length = 1316

 Score =  132 bits (333), Expect = 3e-31,   Method: Compositional matrix adjust.
 Identities = 94/340 (27%), Positives = 173/340 (50%), Gaps = 6/340 (1%)
 Frame = -3

Query: 193  IDIKKYARVEKIPGGIIEDSCVLRGVMINKDVTHPRMRRYIKNPRIVLLDSSLEYKKGES 252
            +D+K    +  + GG +ED+ ++ G++           + I+  +I L+   +   K + 
Sbjct: 1308 VDLKNIKVIRSL-GGTVEDTELVNGLVFTSRSAGTNAPKRIEKAKIGLIQFCISAPKTDM 1132

Query: 253  QTDIEITREEDFTRILQMEEEYIHQLCEDIIQLKPDVVITEKGI-----SDLAQHYLMRA 307
              ++ ++      R+L+ E  YI  + + I +   +V++ +K I     SDLAQH+L + 
Sbjct: 1131 DHNVIVSDYAAMDRVLKEERSYILNIVKQIKKAGCNVLLVQKSILRDAVSDLAQHFLDKI 952

Query: 308  NVTAIRRVRKTDNNRIARACGARIVSRPEELREDDVGTGAGLLEIKKIGDEYFTFITDCK 367
                ++ V + D   + +    R ++  +    +++ + A L+E    G   F  IT  +
Sbjct: 951  KCLVVKDVEREDIEFVCKTLHCRPIASLDHFTAENM-SSADLVEEVASGTNKFVKITGIQ 775

Query: 368  DP-KACTILLRGASKEILSEVERNLQDAMQVCRNVLLDPQLVPGGGASEMAVAHALTEKS 426
            +  +  +I+ RG++K +L E  R+L DA+ V R ++ +   + GGGA E+ +A  L   +
Sbjct: 774  NQGRTVSIICRGSNKLVLEEAARSLHDALCVVRCLVRNRAQIVGGGAPEIEMALQLAAAA 595

Query: 427  KAMTGVEQWPYRAVAQALEVIPRTLIQNCGASTIRLLTSLRAKHTQESCETWGVNGETGT 486
            + + GV+ + YRA A ALEVIP TL +N G + I  +T LR +H Q   +  G+N   G 
Sbjct: 594  QTVDGVDAYCYRAFADALEVIPSTLAENAGLNPIATVTELRNRHAQGE-KNAGINVRKGA 418

Query: 487  LVDMKELGIWEPLAVKLQTYKTAVETAVLLLRIDDIVSGH 526
            + D+    + +PL V       A ET   +L+IDDIV+ +
Sbjct: 417  ITDIFAENVVQPLLVSTSAITLATETVRSILKIDDIVNTY 298
>33770
          Length = 484

 Score =  110 bits (275), Expect = 1e-24,   Method: Compositional matrix adjust.
 Identities = 60/161 (37%), Positives = 104/161 (64%)
 Frame = +1

Query: 48  KMLLDPMGGIVMTNDGNAILREIQVQHPAAKSMIEISRTQDEEVGDGTTSVIILAGEMLS 107
           KM+    G + +TNDG  IL+++QV HPAAK ++E+S+ QD E GDGTT+V++LAG +L 
Sbjct: 1   KMIQAANGDVTITNDGATILKQMQVLHPAAKMLVELSKAQDIEXGDGTTTVVVLAGSLLD 180

Query: 108 VAEHFLEQQMHPTVVISAYRMALDDMISTLKKISTPVDVNNREMMLSIINSSITTKVISR 167
            +   L + +HPT++  A++ A    +  L  +  P+++++RE +LS  ++S+ +KV+S+
Sbjct: 181 ASAKLLAKGIHPTMISEAFQKAASKCVELLDGMVKPLELSDRESLLSSASTSLNSKVVSQ 360

Query: 168 WSSLACNIALDAVKTVQFEENGRKEIDIKKYARVEKIPGGI 208
           +SS+   IA+DAV  V  +      +D+K    ++K+ G I
Sbjct: 361 YSSMLAPIAVDAVLKV-IDPATATNVDLKDIKIIKKLGGTI 480
>02673
          Length = 1243

 Score = 55.5 bits (132), Expect = 5e-08,   Method: Compositional matrix adjust.
 Identities = 34/111 (30%), Positives = 61/111 (54%)
 Frame = +1

Query: 412 GASEMAVAHALTEKSKAMTGVEQWPYRAVAQALEVIPRTLIQNCGASTIRLLTSLRAKHT 471
           GA E+A + A+ E +  ++ +EQ+  R+ ++ALE +P  L +N G + I+ L  ++++  
Sbjct: 1   GAPEIAASVAVAEAADKISTLEQYAVRSFSEALEAVPLALAENSGLAPIQTLAEVKSRQV 180

Query: 472 QESCETWGVNGETGTLVDMKELGIWEPLAVKLQTYKTAVETAVLLLRIDDI 522
           +E     G++       DMKE  + E L  K Q    A +   ++L+IDDI
Sbjct: 181 KEKNPRLGIDCLLKGTNDMKEQNVIETLTAKKQQILLATQLVRMILKIDDI 333
>30661
          Length = 380

 Score = 55.1 bits (131), Expect = 6e-08,   Method: Compositional matrix adjust.
 Identities = 35/100 (35%), Positives = 56/100 (56%)
 Frame = +3

Query: 349 LLEIKKIGDEYFTFITDCKDPKACTILLRGASKEILSEVERNLQDAMQVCRNVLLDPQLV 408
           L+E   IG++     +     +ACTI+LRGA+++IL E  R+L DA+ V    + + + V
Sbjct: 90  LIEEVMIGEDKLIKFSGVALGEACTIVLRGATQQILDEAXRSLHDALCVLSQTVKETRTV 269

Query: 409 PGGGASEMAVAHALTEKSKAMTGVEQWPYRAVAQALEVIP 448
            GGG SEM +A A+++ +    G E       A A+E +P
Sbjct: 270 YGGGCSEMLMAEAVSQLAAKTPGKE-------AIAMEALP 368
>12205
          Length = 564

 Score = 32.0 bits (71), Expect = 0.60,   Method: Compositional matrix adjust.
 Identities = 13/34 (38%), Positives = 24/34 (70%), Gaps = 1/34 (2%)
 Frame = +2

Query: 493 LGIWEPLAVKLQTYKTAVETAVLLLRID-DIVSG 525
           +G+W+ L+ K+  ++TAV+    L+R+D  IV+G
Sbjct: 296 VGVWDNLSCKVGAWRTAVQCVCTLVRMDHGIVTG 397
>12323
          Length = 1455

 Score = 32.0 bits (71), Expect = 0.74,   Method: Compositional matrix adjust.
 Identities = 13/34 (38%), Positives = 24/34 (70%), Gaps = 1/34 (2%)
 Frame = +3

Query: 493 LGIWEPLAVKLQTYKTAVETAVLLLRIDD-IVSG 525
           +G+W+ L+ K+  ++TAV+    L+R+D  IV+G
Sbjct: 903 VGVWDNLSCKVGAWRTAVQCVCTLVRMDHGIVTG 1004
>12624
          Length = 589

 Score = 28.9 bits (63), Expect = 5.5,   Method: Compositional matrix adjust.
 Identities = 13/36 (36%), Positives = 20/36 (55%)
 Frame = +3

Query: 473 ESCETWGVNGETGTLVDMKELGIWEPLAVKLQTYKT 508
           +SCE WG+N     +V  +    W  LA ++ TY+T
Sbjct: 135 KSCEDWGLN---FFMVWTRATHCWRQLAARISTYRT 233
>00104
          Length = 1480

 Score = 28.1 bits (61), Expect = 9.7,   Method: Compositional matrix adjust.
 Identities = 20/64 (31%), Positives = 29/64 (45%)
 Frame = +2

Query: 259 TREEDFTRILQMEEEYIHQLCEDIIQLKPDVVITEKGISDLAQHYLMRANVTAIRRVRKT 318
           T   DFT  L      I   C D+ ++KP + IT+K I        +R  +TA   ++K 
Sbjct: 35  TNVRDFTMFLC-----IFLYCSDMNKIKPTIKITKKAI--------IRIRMTASASIKKA 175

Query: 319 DNNR 322
             NR
Sbjct: 176 TQNR 187
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31560656|ref|NP_032800.2| poly(A) binding protein,
cytoplasmic 1 [Mus musculus]
         (636 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

17775                                                                 601   e-172
39438                                                                 139   3e-33
25691                                                                  78   9e-15
17681                                                                  78   1e-14
30672                                                                  78   1e-14
28652                                                                  72   6e-13
03000                                                                  70   2e-12
02343                                                                  66   5e-11
08958                                                                  65   6e-11
03744                                                                  63   5e-10
20488                                                                  62   6e-10
11687                                                                  60   2e-09
13822                                                                  60   3e-09
16427                                                                  57   2e-08
00302                                                                  56   4e-08
14258                                                                  55   7e-08
01278                                                                  54   2e-07
02140                                                                  54   3e-07
31310                                                                  54   3e-07
14637                                                                  53   4e-07
19868                                                                  51   2e-06
23322                                                                  49   4e-06
02415                                                                  49   5e-06
12506                                                                  49   6e-06
20169                                                                  49   7e-06
13457                                                                  35   8e-06
11019                                                                  48   1e-05
12350                                                                  48   1e-05
02502                                                                  48   2e-05
28455                                                                  47   2e-05
02064                                                                  47   2e-05
00029                                                                  47   2e-05
28605                                                                  47   3e-05
03200                                                                  46   4e-05
03059                                                                  45   1e-04
15371                                                                  44   2e-04
02091                                                                  44   2e-04
25746                                                                  44   3e-04
35379                                                                  43   5e-04
00556                                                                  42   6e-04
33516                                                                  42   7e-04
03903                                                                  42   7e-04
02347                                                                  42   7e-04
29364                                                                  41   0.001
32386                                                                  41   0.002
24983                                                                  40   0.002
09736                                                                  40   0.002
03406                                                                  40   0.003
02809                                                                  40   0.003
15503                                                                  40   0.004
26197                                                                  40   0.004
04988                                                                  40   0.004
23720                                                                  40   0.004
08670                                                                  38   0.011
03097                                                                  37   0.017
10194                                                                  37   0.019
28372                                                                  37   0.024
12096                                                                  37   0.028
05273                                                                  37   0.029
31618                                                                  36   0.037
39789                                                                  35   0.10 
00781                                                                  35   0.10 
25950                                                                  35   0.13 
32733                                                                  35   0.14 
25632                                                                  33   0.25 
11579                                                                  33   0.52 
23655                                                                  32   1.1  
30934                                                                  31   1.8  
11126                                                                  30   2.2  
31265                                                                  30   3.7  
26275                                                                  29   7.1  
19556                                                                  28   7.9  
>17775
          Length = 1282

 Score =  601 bits (1550), Expect = e-172,   Method: Compositional matrix adjust.
 Identities = 290/391 (74%), Positives = 328/391 (83%), Gaps = 1/391 (0%)
 Frame = -2

Query: 1    MNPSAPSYPMASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQ 60
            MN   PSYPMASLYVGDLHPDVTEAML+EKFS AGP+LSIRVCRDMITRRSLGYAYVNFQ
Sbjct: 1224 MNNPGPSYPMASLYVGDLHPDVTEAMLFEKFSTAGPVLSIRVCRDMITRRSLGYAYVNFQ 1045

Query: 61   QPADAERALDTMNFDVIKGKPVRIMWSQRDPSLRKSGVGNIFIKNLDKSIDNKALYDTFS 120
            QPADAERALDTMNFD +KG+P+RIMWSQRDPS+RKSGVGN+FIKNLDK+IDNKALYDTFS
Sbjct: 1044 QPADAERALDTMNFDTVKGRPIRIMWSQRDPSVRKSGVGNVFIKNLDKTIDNKALYDTFS 865

Query: 121  AFGNILSCKVVCDENGSKGYGFVHFETQEAAERAIEKMNGMLLNDRKVFVGRFKSRKERE 180
            AFGNILSCK+ CDE GSKGYGFVHFET+EAA +AI+K+NGMLLN +KV+VGRF  RKER 
Sbjct: 864  AFGNILSCKIACDEQGSKGYGFVHFETEEAARQAIDKVNGMLLNGKKVYVGRFIPRKERI 685

Query: 181  AELGARAKEFTNVYIKNFGEDMDDERLKELFGKF-GPALSVKVMTDESGKSKGFGFVSFE 239
              +G + K F NVY+KNF           L  +     L       E GKS+GFGFVSFE
Sbjct: 684  MMMGDKLKRFNNVYVKNFC*GTG*RPAA*LVWQARQDHLXXGACRGEDGKSRGFGFVSFE 505

Query: 240  RHEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQTELKRKFEQMKQDRITRYQGVNLYVK 299
              E A+KAVDE+NG E++G+ IY GRAQK+ ERQ ELK +FE++K +RI RYQGVNLYVK
Sbjct: 504  EPEGAEKAVDEINGTEVSGRIIYCGRAQKRAERQAELKERFEKIKLERINRYQGVNLYVK 325

Query: 300  NLDDGIDDERLRKEFSPFGTITSAKVMMEGGRSKGFGFVCFSSPEEATKAVTEMNGRIVA 359
            NLDD IDDERLRKEFS FGTITSAK+M EGGRSKGFGFVCFSSPEEATKAVTEMNGRI+ 
Sbjct: 324  NLDDSIDDERLRKEFSNFGTITSAKIMTEGGRSKGFGFVCFSSPEEATKAVTEMNGRIIV 145

Query: 360  TKPLYVALAQRKEERQAHLTNQYMQRMASVR 390
             KPLYVALAQRKE+R+A L ++YMQ MA++R
Sbjct: 144  AKPLYVALAQRKEDRRAQLASRYMQHMANLR 52
>39438
          Length = 2557

 Score =  139 bits (351), Expect = 3e-33,   Method: Compositional matrix adjust.
 Identities = 76/106 (71%), Positives = 84/106 (79%), Gaps = 2/106 (1%)
 Frame = +2

Query: 511 YKYAAGVRNPQQHLNAQPQVTMQQP--AVHVQGQEPLTASMLASAPPQEQKQMLGERLFP 568
           YK    +RN       QP V  Q P  +V + GQEPLTASMLA+APPQEQKQMLGERLFP
Sbjct: 113 YKLNTSMRN--APAGVQPGVMTQAPPQSVVIPGQEPLTASMLAAAPPQEQKQMLGERLFP 286

Query: 569 LIQAMHPSLAGKITGMLLEIDNSELLHMLESPESLRSKVDEAVAVL 614
           LIQ M+P LAGKITGMLLEIDNSELLHMLES ESL++KV+EAVAVL
Sbjct: 287 LIQRMYPDLAGKITGMLLEIDNSELLHMLESQESLKAKVEEAVAVL 424
>25691
          Length = 768

 Score = 78.2 bits (191), Expect = 9e-15,   Method: Compositional matrix adjust.
 Identities = 41/126 (32%), Positives = 77/126 (61%), Gaps = 2/126 (1%)
 Frame = -2

Query: 39  SIRVCRDMITRRSLGYAYVNFQQPADAERALDTMNFDVIKGKPVRIMWSQRDPSLRKSGV 98
           + ++ RD  T +SLGY +VN+++  DA++A+ T+N   ++ K +++  ++  PS      
Sbjct: 434 TCKLIRDKPTGQSLGYGFVNYKRQEDADKAIHTLNGLRLQNKTIKVSLAR--PSCESIKG 261

Query: 99  GNIFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENG--SKGYGFVHFETQEAAERAIE 156
            N++I  L KS+    L + F+  GNI++ +++ D+    SKG GF+ F+ +  AERAI+
Sbjct: 260 ANLYISGLPKSLTQLDLENLFTDCGNIITSRILYDQTTGLSKGVGFIRFDQRIEAERAIQ 81

Query: 157 KMNGML 162
           K+N  +
Sbjct: 80  KLNNHI 63

 Score = 70.5 bits (171), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 46/156 (29%), Positives = 75/156 (48%), Gaps = 5/156 (3%)
 Frame = -2

Query: 219 SVKVMTDE-SGKSKGFGFVSFERHEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQTELK 277
           + K++ D+ +G+S G+GFV+++R EDA KA+  +NG  L  K I V  A+   E      
Sbjct: 434 TCKLIRDKPTGQSLGYGFVNYKRQEDADKAIHTLNGLRLQNKTIKVSLARPSCE------ 273

Query: 278 RKFEQMKQDRITRYQGVNLYVKNLDDGIDDERLRKEFSPFGTITSAKVMME--GGRSKGF 335
                         +G NLY+  L   +    L   F+  G I +++++ +   G SKG 
Sbjct: 272 ------------SIKGANLYISGLPKSLTQLDLENLFTDCGNIITSRILYDQTTGLSKGV 129

Query: 336 GFVCFSSPEEATKAVTEMNGRI--VATKPLYVALAQ 369
           GF+ F    EA +A+ ++N  I      P+ V  A 
Sbjct: 128 GFIRFDQRIEAERAIQKLNNHIPDGCIDPITVKFAN 21

 Score = 68.9 bits (167), Expect = 6e-12,   Method: Compositional matrix adjust.
 Identities = 40/129 (31%), Positives = 76/129 (58%), Gaps = 3/129 (2%)
 Frame = -2

Query: 127 SCKVVCDE--NGSKGYGFVHFETQEAAERAIEKMNGMLLNDRKVFVGRFKSRKEREAELG 184
           +CK++ D+    S GYGFV+++ QE A++AI  +NG+ L ++ + V    +R   E+  G
Sbjct: 434 TCKLIRDKPTGQSLGYGFVNYKRQEDADKAIHTLNGLRLQNKTIKVSL--ARPSCESIKG 261

Query: 185 ARAKEFTNVYIKNFGEDMDDERLKELFGKFGPALSVKVMTDE-SGKSKGFGFVSFERHED 243
           A      N+YI    + +    L+ LF   G  ++ +++ D+ +G SKG GF+ F++  +
Sbjct: 260 A------NLYISGLPKSLTQLDLENLFTDCGNIITSRILYDQTTGLSKGVGFIRFDQRIE 99

Query: 244 AQKAVDEMN 252
           A++A+ ++N
Sbjct: 98  AERAIQKLN 72
>17681
          Length = 964

 Score = 77.8 bits (190), Expect = 1e-14,   Method: Compositional matrix adjust.
 Identities = 61/205 (29%), Positives = 90/205 (43%), Gaps = 45/205 (21%)
 Frame = +2

Query: 13  LYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQPADAERALDTM 72
           ++VGDL P++    L E F+P G I + R+ RD  T +S GYA+V+F + A+AE A+  M
Sbjct: 38  IFVGDLSPEIETETLREAFAPFGEISNCRIVRDPQTMKSKGYAFVSFVKKAEAENAIQAM 217

Query: 73  NFDVIKGKPVRIMWSQRD-PSLRKSG-----------------VGNIFIKNLDKS----- 109
           N   I  + +R  WS R  P  R+S                       IKN  +      
Sbjct: 218 NGQWIGSRSIRTNWSTRKLPPPRESSKSGGQGGGMGGMGGCGGGAGNGIKNNQRHTFEEV 397

Query: 110 --------------------IDNKALYDTFSAFGNILSCKVVCDENGSKGYGFVHFETQE 149
                               I ++ ++  F  FG I   +V  D    KG+ F+ F T+E
Sbjct: 398 YNQSSPTNTTVYCGGFPPNVISDELMHKHFMQFGPIQDVRVFKD----KGFAFIKFVTKE 565

Query: 150 AAERAIE--KMNGMLLNDRKVFVGR 172
           AA RAIE   ++ +  N  K F G+
Sbjct: 566 AAARAIEHTHISEVHGNHVKCFWGK 640

 Score = 69.7 bits (169), Expect = 3e-12,   Method: Compositional matrix adjust.
 Identities = 54/210 (25%), Positives = 84/210 (40%), Gaps = 39/210 (18%)
 Frame = +2

Query: 91  PSLRKSGVGNIFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENG--SKGYGFVHFETQ 148
           P    S   +IF+ +L   I+ + L + F+ FG I +C++V D     SKGY FV F  +
Sbjct: 8   PKTDISSHHHIFVGDLSPEIETETLREAFAPFGEISNCRIVRDPQTMKSKGYAFVSFVKK 187

Query: 149 EAAERAIEKMNGMLLNDRKVFVG------------------------------------R 172
             AE AI+ MNG  +  R +                                       +
Sbjct: 188 AEAENAIQAMNGQWIGSRSIRTNWSTRKLPPPRESSKSGGQGGGMGGMGGCGGGAGNGIK 367

Query: 173 FKSRKEREAELGARAKEFTNVYIKNFGED-MDDERLKELFGKFGPALSVKVMTDESGKSK 231
              R   E      +   T VY   F  + + DE + + F +FGP   V+V  D     K
Sbjct: 368 NNQRHTFEEVYNQSSPTNTTVYCGGFPPNVISDELMHKHFMQFGPIQDVRVFKD-----K 532

Query: 232 GFGFVSFERHEDAQKAVDEMNGKELNGKQI 261
           GF F+ F   E A +A++  +  E++G  +
Sbjct: 533 GFAFIKFVTKEAAARAIEHTHISEVHGNHV 622

 Score = 60.1 bits (144), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 46/193 (23%), Positives = 84/193 (43%), Gaps = 34/193 (17%)
 Frame = +2

Query: 192 NVYIKNFGEDMDDERLKELFGKFGPALSVKVMTD-ESGKSKGFGFVSFERHEDAQKAVDE 250
           ++++ +   +++ E L+E F  FG   + +++ D ++ KSKG+ FVSF +  +A+ A+  
Sbjct: 35  HIFVGDLSPEIETETLREAFAPFGEISNCRIVRDPQTMKSKGYAFVSFVKKAEAENAIQA 214

Query: 251 MNGKELNGKQIYVGRAQKKV---------------------------------ERQTELK 277
           MNG+ +  + I    + +K+                                 +R T  +
Sbjct: 215 MNGQWIGSRSIRTNWSTRKLPPPRESSKSGGQGGGMGGMGGCGGGAGNGIKNNQRHT-FE 391

Query: 278 RKFEQMKQDRITRYQGVNLYVKNLDDGIDDERLRKEFSPFGTITSAKVMMEGGRSKGFGF 337
             + Q      T Y G   +  N+   I DE + K F  FG I   +V     + KGF F
Sbjct: 392 EVYNQSSPTNTTVYCG--GFPPNV---ISDELMHKHFMQFGPIQDVRVF----KDKGFAF 544

Query: 338 VCFSSPEEATKAV 350
           + F + E A +A+
Sbjct: 545 IKFVTKEAAARAI 583

 Score = 53.5 bits (127), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 25/79 (31%), Positives = 47/79 (59%), Gaps = 2/79 (2%)
 Frame = +2

Query: 295 NLYVKNLDDGIDDERLRKEFSPFGTITSAKVMME--GGRSKGFGFVCFSSPEEATKAVTE 352
           +++V +L   I+ E LR+ F+PFG I++ +++ +    +SKG+ FV F    EA  A+  
Sbjct: 35  HIFVGDLSPEIETETLREAFAPFGEISNCRIVRDPQTMKSKGYAFVSFVKKAEAENAIQA 214

Query: 353 MNGRIVATKPLYVALAQRK 371
           MNG+ + ++ +    + RK
Sbjct: 215 MNGQWIGSRSIRTNWSTRK 271
>30672
          Length = 877

 Score = 77.8 bits (190), Expect = 1e-14,   Method: Compositional matrix adjust.
 Identities = 66/227 (29%), Positives = 107/227 (47%), Gaps = 34/227 (14%)
 Frame = +3

Query: 192 NVYIKNFGEDMDDERLKELFGKFGPALSVKVMT-DESGKSKGFGFVSFERHEDAQKAVDE 250
            ++++N   +  +E+L E F + GP  +  V+   E GK +GFG+V F   EDA KA D 
Sbjct: 15  TLFVRNLPFETSNEKLLEAFEQVGPLKTAFVVAGKEPGKCRGFGYVQFSMLEDAIKAKDT 194

Query: 251 MNGKELNGKQIYVGRAQ----------------------KKVERQTEL----------KR 278
           +     +G++I +  A                       KK+  QT +          K+
Sbjct: 195 VT--HCSGRKISLSFADTKKSWKTKQKGGTETSDALGLGKKLPSQTAVTDGEPNPKPEKK 368

Query: 279 KFEQMKQDRITRYQGVNLYVKNLDDGIDDERLRKEFSPFGTITSAKV-MMEGGRSKGFGF 337
           K +Q KQ+   R     L ++NL     +  +R  F  FGTI+   + + +G RS+GF F
Sbjct: 369 KTKQPKQELGKR---CRLIIRNLAFKCKEADIRSHFGKFGTISEVTIPLKQGDRSRGFAF 539

Query: 338 VCFSSPEEATKAVTEMNGRIVATKPLYVALAQRKEERQAHLTNQYMQ 384
           V F+  + A KA+++MNG  +  +P+ V  A  K+  +A  T Q  Q
Sbjct: 540 VQFTEVKAAQKAISDMNGTAIMDRPVAVDWAVAKDRFEAS-TQQNQQ 677

 Score = 49.3 bits (116), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 50/212 (23%), Positives = 83/212 (39%), Gaps = 45/212 (21%)
 Frame = +3

Query: 100 NIFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENGSK--GYGFVHFETQEAAERAIEK 157
            +F++NL     N+ L + F   G + +  VV  +   K  G+G+V F   E A +A + 
Sbjct: 15  TLFVRNLPFETSNEKLLEAFEQVGPLKTAFVVAGKEPGKCRGFGYVQFSMLEDAIKAKDT 194

Query: 158 MNGMLLNDRKV---FVGRFKSRKEREA--------------------------------- 181
           +     + RK+   F    KS K ++                                  
Sbjct: 195 VTH--CSGRKISLSFADTKKSWKTKQKGGTETSDALGLGKKLPSQTAVTDGEPNPKPEKK 368

Query: 182 -------ELGARAKEFTNVYIKNFGEDMDDERLKELFGKFGPALSVKVMTDESGKSKGFG 234
                  ELG R +    + I+N      +  ++  FGKFG    V +   +  +S+GF 
Sbjct: 369 KTKQPKQELGKRCR----LIIRNLAFKCKEADIRSHFGKFGTISEVTIPLKQGDRSRGFA 536

Query: 235 FVSFERHEDAQKAVDEMNGKELNGKQIYVGRA 266
           FV F   + AQKA+ +MNG  +  + + V  A
Sbjct: 537 FVQFTEVKAAQKAISDMNGTAIMDRPVAVDWA 632

 Score = 35.4 bits (80), Expect = 0.070,   Method: Compositional matrix adjust.
 Identities = 21/75 (28%), Positives = 35/75 (46%)
 Frame = +3

Query: 13  LYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQPADAERALDTM 72
           L + +L     EA +   F   G I  + +       RS G+A+V F +   A++A+  M
Sbjct: 411 LIIRNLAFKCKEADIRSHFGKFGTISEVTIPLKQ-GDRSRGFAFVQFTEVKAAQKAISDM 587

Query: 73  NFDVIKGKPVRIMWS 87
           N   I  +PV + W+
Sbjct: 588 NGTAIMDRPVAVDWA 632
>28652
          Length = 918

 Score = 72.4 bits (176), Expect = 6e-13,   Method: Compositional matrix adjust.
 Identities = 67/266 (25%), Positives = 120/266 (45%), Gaps = 15/266 (5%)
 Frame = -2

Query: 13  LYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQ-QPADAERALDT 71
           ++ G +  D+ E  L   F   G I  +R+  D ++  + GY +V +  + A AE     
Sbjct: 725 VFCGKIPRDIFEDELIPLFEDCGTIWDLRLMMDPVSNLNRGYCFVTYTTKEAAAEAVKQH 546

Query: 72  MNFDVIKGKPVRIMWSQRDPSLRKSGVGNIFIKNLDKSIDNKALYDTFSAFGNILSCKVV 131
             +++ KGK +++  S   P+LR      +F+ N+ KS   + +   F      L   +V
Sbjct: 545 DGYEIRKGKKLKVNISI--PNLR------LFVGNIPKSKTKEEILKEFEKHSEGLMDVIV 390

Query: 132 CDENGS-----KGYGFVHFETQEAAERAIEKMNGMLLNDRKVFVGRFKSRKEREAELGAR 186
                +     +G+ F+ ++T + A  A           R+   GRF+  +       A 
Sbjct: 389 YGSADNPKLKNRGFAFLEYDTHKNASAA----------KRRFTTGRFRVWQCDVIVDWAD 240

Query: 187 AKEFTN---------VYIKNFGEDMDDERLKELFGKFGPALSVKVMTDESGKSKGFGFVS 237
            +E  N         +Y++N   D+ ++ LKE FG +G    VK       K K +GFV 
Sbjct: 239 LQEEPNEETMSKVKVLYVRNLTGDVTEDDLKEKFGAYGKVERVK-------KIKDYGFVH 81

Query: 238 FERHEDAQKAVDEMNGKELNGKQIYV 263
           +E  EDA KA+D+++G+++   +I V
Sbjct: 80  YEDREDALKALDDLHGEKIGNLEIDV 3
>03000
          Length = 778

 Score = 70.1 bits (170), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 53/177 (29%), Positives = 95/177 (53%), Gaps = 8/177 (4%)
 Frame = +3

Query: 101 IFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENG--SKGYGFVHFETQEAAERAI--- 155
           +FI  L    D  +L   F  +G I+ C V+ D N   S+G+GF+ ++  E+ ++A    
Sbjct: 93  LFIGGLSYETDEDSLRSHFETWGEIVDCIVMRDSNSKRSRGFGFITYKDAESIDQAQANR 272

Query: 156 -EKMNGMLLNDRKVFVGRFKSRKER-EAELGARAKEFTNVYIKNFGEDMDDERLKELFGK 213
             K++G     R+V   R   R+E   +E+    K+   +++    ED  ++ +++ F +
Sbjct: 273 PHKIDG-----REVDTKRAMPREESGRSEVQQSVKK---MFVGGVKEDTTEDMIRDTFNE 428

Query: 214 FGPALSVKVMTDE-SGKSKGFGFVSFERHEDAQKAVDEMNGKELNGKQIYVGRAQKK 269
           FG    V ++ D+ +GK++GF FV+F  H+   KAV +    +LNG+Q+ V +AQ K
Sbjct: 429 FGEITGVDLIQDKGTGKNRGFCFVTFGDHDSVDKAVLKKR-HDLNGRQVEVKKAQSK 596

 Score = 58.9 bits (141), Expect = 6e-09,   Method: Compositional matrix adjust.
 Identities = 49/188 (26%), Positives = 89/188 (47%), Gaps = 8/188 (4%)
 Frame = +3

Query: 182 ELGARAKEFTNVYIKNFGEDMDDERLKELFGKFGPALSVKVMTDESGK-SKGFGFVSFER 240
           +L   A++F  ++I     + D++ L+  F  +G  +   VM D + K S+GFGF++++ 
Sbjct: 60  DLDPNAEQFRKLFIGGLSYETDEDSLRSHFETWGEIVDCIVMRDSNSKRSRGFGFITYKD 239

Query: 241 HEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQTELKRKFEQMKQDRITRYQGVN-LYVK 299
            E    ++D          Q    R  K   R+ + KR   + +  R    Q V  ++V 
Sbjct: 240 AE----SID----------QAQANRPHKIDGREVDTKRAMPREESGRSEVQQSVKKMFVG 377

Query: 300 NLDDGIDDERLRKEFSPFGTITSAKVMME--GGRSKGFGFVCFSSPEEATKAVT----EM 353
            + +   ++ +R  F+ FG IT   ++ +   G+++GF FV F   +   KAV     ++
Sbjct: 378 GVKEDTTEDMIRDTFNEFGEITGVDLIQDKGTGKNRGFCFVTFGDHDSVDKAVLKKRHDL 557

Query: 354 NGRIVATK 361
           NGR V  K
Sbjct: 558 NGRQVEVK 581
>02343
          Length = 1715

 Score = 65.9 bits (159), Expect = 5e-11,   Method: Compositional matrix adjust.
 Identities = 45/191 (23%), Positives = 85/191 (44%), Gaps = 4/191 (2%)
 Frame = -2

Query: 191  TNVYIKNFGEDMDDERLKELFGKFGPALSVKVMTDES-GKSKGFGFVSFERHEDAQKAVD 249
            TN+YI+    +  D+ L  L   FG   S K + D++  K KG+GFV F+    A++AV 
Sbjct: 1264 TNLYIRGLSPNTTDKDLVNLCQHFGTITSTKAIIDQTTNKCKGYGFVDFDAPGAAERAVQ 1085

Query: 250  EMNGKELNGKQIYVGRAQKKVERQTELKRKFEQMKQDRITRYQGVNLYVKNLDDGIDDER 309
             +  + +                Q ++ ++ EQ            NLY+ NL     ++ 
Sbjct: 1084 ALQAQGI----------------QAQMAKQQEQ---------DPTNLYIANLPLHFTEKH 980

Query: 310  LRKEFSPFGTITSAKVMME-GGRSKGFGFVCFSSPEEATKAVTEMNGRIV--ATKPLYVA 366
            L   F  +GT+ S +++ +  G S+  GF    S ++    +   N +++   ++PL V 
Sbjct: 979  LEGLFKDYGTVISTRILRKPDGISRCVGFARMESRDKCDTVINTFNNKMISGCSEPLLVK 800

Query: 367  LAQRKEERQAH 377
             A    ++++ 
Sbjct: 799  FADSGNKKKSQ 767

 Score = 62.4 bits (150), Expect = 5e-10,   Method: Compositional matrix adjust.
 Identities = 39/154 (25%), Positives = 72/154 (46%), Gaps = 1/154 (0%)
 Frame = -2

Query: 12   SLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQPADAERALDT 71
            +LY+  L P+ T+  L       G I S +   D  T +  GY +V+F  P  AERA+  
Sbjct: 1261 NLYIRGLSPNTTDKDLVNLCQHFGTITSTKAIIDQTTNKCKGYGFVDFDAPGAAERAVQA 1082

Query: 72   MNFDVIKGKPVRIMWSQRDPSLRKSGVGNIFIKNLDKSIDNKALYDTFSAFGNILSCKVV 131
            +    I+ +  +    ++DP+       N++I NL      K L   F  +G ++S +++
Sbjct: 1081 LQAQGIQAQMAK--QQEQDPT-------NLYIANLPLHFTEKHLEGLFKDYGTVISTRIL 929

Query: 132  CDENG-SKGYGFVHFETQEAAERAIEKMNGMLLN 164
               +G S+  GF   E+++  +  I   N  +++
Sbjct: 928  RKPDGISRCVGFARMESRDKCDTVINTFNNKMIS 827

 Score = 46.6 bits (109), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 28/95 (29%), Positives = 47/95 (49%), Gaps = 2/95 (2%)
 Frame = -2

Query: 294  VNLYVKNLDDGIDDERLRKEFSPFGTITSAKVMME--GGRSKGFGFVCFSSPEEATKAVT 351
             NLY++ L     D+ L      FGTITS K +++    + KG+GFV F +P  A +AV 
Sbjct: 1264 TNLYIRGLSPNTTDKDLVNLCQHFGTITSTKAIIDQTTNKCKGYGFVDFDAPGAAERAVQ 1085

Query: 352  EMNGRIVATKPLYVALAQRKEERQAHLTNQYMQRM 386
             +  + +         AQ  ++++   TN Y+  +
Sbjct: 1084 ALQAQGIQ--------AQMAKQQEQDPTNLYIANL 1004
>08958
          Length = 680

 Score = 65.5 bits (158), Expect = 6e-11,   Method: Compositional matrix adjust.
 Identities = 46/154 (29%), Positives = 81/154 (52%), Gaps = 3/154 (1%)
 Frame = +2

Query: 13  LYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQPADAER-ALDT 71
           L+VG+L PDV+E    + FSP G +    V     + R  G+  ++++  A+A + ALD 
Sbjct: 74  LFVGNLTPDVSEDDFKKLFSPFGEVSEAYVN----SGRGFGFIRLDYRHNAEAAKAALDG 241

Query: 72  MNFDVIKGKPVRIMWSQRDPSLRKSGVGNIFIKNLDKSIDNKALYDTFSAFGNILSCKVV 131
           +     KG+ +R+ ++    +L+        +KNL   + N+ L   F+ FG++    V+
Sbjct: 242 LQ---RKGRSLRVRYATHGAALK--------VKNLHPYVSNELLEQAFTQFGDLERAIVI 388

Query: 132 CDENG-SKGYGFVHFETQEAAERAIEKMN-GMLL 163
            DE G S G G V F  +  A++A+ ++N G+ L
Sbjct: 389 VDERGRSTGEGVVEFVRKPGAQQALRRINEGVFL 490

 Score = 57.4 bits (137), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 45/157 (28%), Positives = 70/157 (44%)
 Frame = +2

Query: 96  SGVGNIFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENGSKGYGFVHFETQEAAERAI 155
           +G   +F+ NL   +        FS FG +    V    N  +G+GF+  + +  AE A 
Sbjct: 59  TGRCRLFVGNLTPDVSEDDFKKLFSPFGEVSEAYV----NSGRGFGFIRLDYRHNAEAAK 226

Query: 156 EKMNGMLLNDRKVFVGRFKSRKEREAELGARAKEFTNVYIKNFGEDMDDERLKELFGKFG 215
             ++G+    R + V        R A  GA  K      +KN    + +E L++ F +FG
Sbjct: 227 AALDGLQRKGRSLRV--------RYATHGAALK------VKNLHPYVSNELLEQAFTQFG 364

Query: 216 PALSVKVMTDESGKSKGFGFVSFERHEDAQKAVDEMN 252
                 V+ DE G+S G G V F R   AQ+A+  +N
Sbjct: 365 DLERAIVIVDERGRSTGEGVVEFVRKPGAQQALRRIN 475

 Score = 51.6 bits (122), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 51/196 (26%), Positives = 84/196 (42%), Gaps = 8/196 (4%)
 Frame = +2

Query: 186 RAKEFTN---VYIKNFGEDMDDERLKELFGKFGPALSVKVMTDESGKSKGFGFVSFERHE 242
           R K+FT    +++ N   D+ ++  K+LF  FG      V +      +GFGF+  +   
Sbjct: 44  RRKKFTGRCRLFVGNLTPDVSEDDFKKLFSPFGEVSEAYVNS-----GRGFGFIRLDYRH 208

Query: 243 DAQKAVDEMNGKELNGKQIYVGRAQKKVERQTELKRKFEQMKQDRITRYQGVNLYVKNLD 302
           +A+ A   ++G +  G+ + V  A                          G  L VKNL 
Sbjct: 209 NAEAAKAALDGLQRKGRSLRVRYAT------------------------HGAALKVKNLH 316

Query: 303 DGIDDERLRKEFSPFGTITSAKVMM-EGGRSKGFGFVCFSSPEEATKAVTEMNGRIVAT- 360
             + +E L + F+ FG +  A V++ E GRS G G V F     A +A+  +N  +    
Sbjct: 317 PYVSNELLEQAFTQFGDLERAIVIVDERGRSTGEGVVEFVRKPGAQQALRRINEGVFLFG 496

Query: 361 ---KPLYVALAQRKEE 373
              KP+ V   + K+E
Sbjct: 497 ADPKPIEVEPLEHKDE 544
>03744
          Length = 3486

 Score = 62.8 bits (151), Expect = 5e-10,   Method: Compositional matrix adjust.
 Identities = 34/90 (37%), Positives = 49/90 (54%), Gaps = 2/90 (2%)
 Frame = -1

Query: 287  RITRYQGVNLYVKNLDDGIDDERLRKEFSPFGTITSAKVMME--GGRSKGFGFVCFSSPE 344
            R+    G NL++ +L     D+ L + F PFG + SAKV ++     SK FGFV + SP 
Sbjct: 3237 RVPGPDGANLFIYHLPQEFGDQDLMQMFMPFGNVVSAKVFIDKQTNLSKCFGFVSYDSPL 3058

Query: 345  EATKAVTEMNGRIVATKPLYVALAQRKEER 374
             A  A+T MNG  +  K L V L + K ++
Sbjct: 3057 AAQAAITSMNGFQIGMKRLKVQLKRSKNDK 2968

 Score = 52.0 bits (123), Expect = 7e-07,   Method: Compositional matrix adjust.
 Identities = 28/82 (34%), Positives = 49/82 (59%), Gaps = 2/82 (2%)
 Frame = -1

Query: 100  NIFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDE--NGSKGYGFVHFETQEAAERAIEK 157
            N+FI +L +   ++ L   F  FGN++S KV  D+  N SK +GFV +++  AA+ AI  
Sbjct: 3213 NLFIYHLPQEFGDQDLMQMFMPFGNVVSAKVFIDKQTNLSKCFGFVSYDSPLAAQAAITS 3034

Query: 158  MNGMLLNDRKVFVGRFKSRKER 179
            MNG  +  +++ V   +S+ ++
Sbjct: 3033 MNGFQIGMKRLKVQLKRSKNDK 2968

 Score = 49.3 bits (116), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 27/83 (32%), Positives = 48/83 (57%), Gaps = 1/83 (1%)
 Frame = -1

Query: 191  TNVYIKNFGEDMDDERLKELFGKFGPALSVKVMTD-ESGKSKGFGFVSFERHEDAQKAVD 249
             N++I +  ++  D+ L ++F  FG  +S KV  D ++  SK FGFVS++    AQ A+ 
Sbjct: 3216 ANLFIYHLPQEFGDQDLMQMFMPFGNVVSAKVFIDKQTNLSKCFGFVSYDSPLAAQAAIT 3037

Query: 250  EMNGKELNGKQIYVGRAQKKVER 272
             MNG ++  K++ V   + K ++
Sbjct: 3036 SMNGFQIGMKRLKVQLKRSKNDK 2968
>20488
          Length = 3281

 Score = 62.4 bits (150), Expect = 6e-10,   Method: Compositional matrix adjust.
 Identities = 33/84 (39%), Positives = 47/84 (55%), Gaps = 2/84 (2%)
 Frame = +2

Query: 293  GVNLYVKNLDDGIDDERLRKEFSPFGTITSAKVMME--GGRSKGFGFVCFSSPEEATKAV 350
            G NL++ +L     D+ L + F PFG + SAKV ++     SK FGFV + SP  A  A+
Sbjct: 2705 GANLFIYHLPQEFGDQDLMQMFMPFGNVVSAKVFIDKQTNLSKCFGFVSYDSPLAAQAAI 2884

Query: 351  TEMNGRIVATKPLYVALAQRKEER 374
            T MNG  +  K L V L + K ++
Sbjct: 2885 TSMNGFQIGMKRLKVQLKRSKNDK 2956

 Score = 51.2 bits (121), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 28/82 (34%), Positives = 49/82 (59%), Gaps = 2/82 (2%)
 Frame = +2

Query: 100  NIFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDE--NGSKGYGFVHFETQEAAERAIEK 157
            N+FI +L +   ++ L   F  FGN++S KV  D+  N SK +GFV +++  AA+ AI  
Sbjct: 2711 NLFIYHLPQEFGDQDLMQMFMPFGNVVSAKVFIDKQTNLSKCFGFVSYDSPLAAQAAITS 2890

Query: 158  MNGMLLNDRKVFVGRFKSRKER 179
            MNG  +  +++ V   +S+ ++
Sbjct: 2891 MNGFQIGMKRLKVQLKRSKNDK 2956

 Score = 49.3 bits (116), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 27/83 (32%), Positives = 48/83 (57%), Gaps = 1/83 (1%)
 Frame = +2

Query: 191  TNVYIKNFGEDMDDERLKELFGKFGPALSVKVMTD-ESGKSKGFGFVSFERHEDAQKAVD 249
             N++I +  ++  D+ L ++F  FG  +S KV  D ++  SK FGFVS++    AQ A+ 
Sbjct: 2708 ANLFIYHLPQEFGDQDLMQMFMPFGNVVSAKVFIDKQTNLSKCFGFVSYDSPLAAQAAIT 2887

Query: 250  EMNGKELNGKQIYVGRAQKKVER 272
             MNG ++  K++ V   + K ++
Sbjct: 2888 SMNGFQIGMKRLKVQLKRSKNDK 2956
>11687
          Length = 676

 Score = 60.5 bits (145), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 48/175 (27%), Positives = 84/175 (48%), Gaps = 16/175 (9%)
 Frame = +3

Query: 1   MNPSA-------PSYPMASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLG 53
           MNPS        P      ++VG +  ++ E  L + F   GP+ S+ + RD  T +S G
Sbjct: 99  MNPSTQVTSQGEPDADSIKMFVGQIPRNMDENELRKMFEDYGPVHSLNILRDKNTGQSKG 278

Query: 54  YAYVNF---QQPADAERALDTMNFDVIKGKPVRIMWSQRDPSLRKSGVGNI-----FIKN 105
             +V F   +   DA+ AL  +    +   PV++  +    S +++G  N+     F+  
Sbjct: 279 CCFVTFFTRKAALDAQNALHNVKTMPMMHHPVQMKPAD---SEKRNGERNVEERKLFVGM 449

Query: 106 LDKSIDNKALYDTFSAFGNILSCKVVCDENG-SKGYGFVHFETQEAAERAIEKMN 159
           L K +    +   F +FG+I  C V+ D NG S+G  F+ F +++ A  +I+ M+
Sbjct: 450 LSKKLSENDVRMLFESFGSIDDCTVLRDSNGTSRGCAFITFASRQCAMNSIKGMH 614

 Score = 55.1 bits (131), Expect = 8e-08,   Method: Compositional matrix adjust.
 Identities = 45/184 (24%), Positives = 87/184 (47%), Gaps = 8/184 (4%)
 Frame = +3

Query: 193 VYIKNFGEDMDDERLKELFGKFGPALSVKVMTDE-SGKSKGFGFVSFERHE---DAQKAV 248
           +++     +MD+  L+++F  +GP  S+ ++ D+ +G+SKG  FV+F   +   DAQ A+
Sbjct: 156 MFVGQIPRNMDENELRKMFEDYGPVHSLNILRDKNTGQSKGCCFVTFFTRKAALDAQNAL 335

Query: 249 DEMNGKELNGKQIYVGRAQKKVERQTELKRKFEQMKQDRITRYQGVNLYVKNLDDGIDDE 308
             +    +    + +  A  +       KR  E+  ++R        L+V  L   + + 
Sbjct: 336 HNVKTMPMMHHPVQMKPADSE-------KRNGERNVEER-------KLFVGMLSKKLSEN 473

Query: 309 RLRKEFSPFGTITSAKVMME-GGRSKGFGFVCFSSPEEATKAVTEMNGRIV---ATKPLY 364
            +R  F  FG+I    V+ +  G S+G  F+ F+S + A  ++  M+        + PL 
Sbjct: 474 DVRMLFESFGSIDDCTVLRDSNGTSRGCAFITFASRQCAMNSIKGMHHSQTMEGCSSPLV 653

Query: 365 VALA 368
           V +A
Sbjct: 654 VKMA 665
>13822
          Length = 963

 Score = 60.1 bits (144), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 29/78 (37%), Positives = 48/78 (61%)
 Frame = -1

Query: 193 VYIKNFGEDMDDERLKELFGKFGPALSVKVMTDESGKSKGFGFVSFERHEDAQKAVDEMN 252
           +++ N      +  L++L G FG  L V+++ +E G SKGFGFV+F    +A++A D+MN
Sbjct: 336 LHVSNIPFRFREADLRQLLGPFGTILDVEIIFNERG-SKGFGFVTFAHSAEAERARDKMN 160

Query: 253 GKELNGKQIYVGRAQKKV 270
           G  + G++I V  A  +V
Sbjct: 159 GTVVEGRKIEVNNATARV 106

 Score = 56.2 bits (134), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 27/76 (35%), Positives = 40/76 (52%)
 Frame = -1

Query: 101 IFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENGSKGYGFVHFETQEAAERAIEKMNG 160
           + + N+        L      FG IL  +++ +E GSKG+GFV F     AERA +KMNG
Sbjct: 336 LHVSNIPFRFREADLRQLLGPFGTILDVEIIFNERGSKGFGFVTFAHSAEAERARDKMNG 157

Query: 161 MLLNDRKVFVGRFKSR 176
            ++  RK+ V    +R
Sbjct: 156 TVVEGRKIEVNNATAR 109

 Score = 52.0 bits (123), Expect = 7e-07,   Method: Compositional matrix adjust.
 Identities = 39/133 (29%), Positives = 61/133 (45%), Gaps = 4/133 (3%)
 Frame = -1

Query: 266 AQKKVERQTELKRKFE----QMKQDRITRYQGVNLYVKNLDDGIDDERLRKEFSPFGTIT 321
           A   VE+ TE+    E    Q+    I+      L+V N+     +  LR+   PFGTI 
Sbjct: 438 ANGTVEQSTEVNSDGEVQGVQVPPQAISPEGPKRLHVSNIPFRFREADLRQLLGPFGTIL 259

Query: 322 SAKVMMEGGRSKGFGFVCFSSPEEATKAVTEMNGRIVATKPLYVALAQRKEERQAHLTNQ 381
             +++     SKGFGFV F+   EA +A  +MNG +V  + + V  A          T +
Sbjct: 258 DVEIIFNERGSKGFGFVTFAHSAEAERARDKMNGTVVEGRKIEVNNA----------TAR 109

Query: 382 YMQRMASVRAVPN 394
            M +  +  ++PN
Sbjct: 108 VMTKKVAAPSIPN 70
>16427
          Length = 1313

 Score = 57.4 bits (137), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 32/77 (41%), Positives = 49/77 (63%), Gaps = 2/77 (2%)
 Frame = +1

Query: 296 LYVKNLDDGIDDERLRKEFSPFGTITSAKVMMEGGR--SKGFGFVCFSSPEEATKAVTEM 353
           L+V  L + ID++ L +EFS FG IT + V+ +  R  S+GFGFV + +P +A +AV  M
Sbjct: 142 LFVGGLAEEIDEKVLEREFSKFGRITESMVIRDKVRQVSRGFGFVTYENPMDAEEAVKHM 321

Query: 354 NGRIVATKPLYVALAQR 370
           +G+ +  K L+V  A R
Sbjct: 322 DGKEILGKKLHVEDAVR 372

 Score = 54.7 bits (130), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 27/72 (37%), Positives = 48/72 (66%), Gaps = 1/72 (1%)
 Frame = +1

Query: 193 VYIKNFGEDMDDERLKELFGKFGPALSVKVMTDESGK-SKGFGFVSFERHEDAQKAVDEM 251
           +++    E++D++ L+  F KFG      V+ D+  + S+GFGFV++E   DA++AV  M
Sbjct: 142 LFVGGLAEEIDEKVLEREFSKFGRITESMVIRDKVRQVSRGFGFVTYENPMDAEEAVKHM 321

Query: 252 NGKELNGKQIYV 263
           +GKE+ GK+++V
Sbjct: 322 DGKEILGKKLHV 357
>00302
          Length = 927

 Score = 56.2 bits (134), Expect = 4e-08,   Method: Compositional matrix adjust.
 Identities = 26/58 (44%), Positives = 42/58 (72%), Gaps = 1/58 (1%)
 Frame = -1

Query: 207 LKELFGKFGPALSVKVMTD-ESGKSKGFGFVSFERHEDAQKAVDEMNGKELNGKQIYV 263
           L+E+FG++G    V+V+ D ++G+S+GF FV F+  EDA +A D  NG E++G++I V
Sbjct: 417 LREVFGRYGHISEVQVVYDRQTGRSRGFAFVYFKSSEDAHEAKDRCNGIEIDGRKIRV 244

 Score = 42.4 bits (98), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 20/60 (33%), Positives = 36/60 (60%), Gaps = 2/60 (3%)
 Frame = -1

Query: 113 KALYDTFSAFGNILSCKVVCDENG--SKGYGFVHFETQEAAERAIEKMNGMLLNDRKVFV 170
           + L + F  +G+I   +VV D     S+G+ FV+F++ E A  A ++ NG+ ++ RK+ V
Sbjct: 423 RGLREVFGRYGHISEVQVVYDRQTGRSRGFAFVYFKSSEDAHEAKDRCNGIEIDGRKIRV 244

 Score = 38.1 bits (87), Expect = 0.011,   Method: Compositional matrix adjust.
 Identities = 24/78 (30%), Positives = 41/78 (52%), Gaps = 2/78 (2%)
 Frame = -1

Query: 293 GVNLYVKNLDDGIDDERLRKEFSPFGTITSAKVMME--GGRSKGFGFVCFSSPEEATKAV 350
           G++LY +       +  LR+ F  +G I+  +V+ +   GRS+GF FV F S E+A +A 
Sbjct: 447 GLSLYTQ-------ERGLREVFGRYGHISEVQVVYDRQTGRSRGFAFVYFKSSEDAHEAK 289

Query: 351 TEMNGRIVATKPLYVALA 368
              NG  +  + + V  +
Sbjct: 288 DRCNGIEIDGRKIRVDFS 235
>14258
          Length = 1063

 Score = 55.5 bits (132), Expect = 7e-08,   Method: Compositional matrix adjust.
 Identities = 29/73 (39%), Positives = 42/73 (57%), Gaps = 2/73 (2%)
 Frame = +2

Query: 304 GIDDERLRKEFSPFGTITSAKVMME--GGRSKGFGFVCFSSPEEATKAVTEMNGRIVATK 361
           G+ D+ L + F PFG + SAKV ++     SK FGFV + SP  A  A++ MNG  +  K
Sbjct: 92  GVGDQDLMQMFMPFGNVISAKVFIDKQTNLSKCFGFVSYDSPMSAQDAISSMNGFQIGMK 271

Query: 362 PLYVALAQRKEER 374
            L V L + K ++
Sbjct: 272 RLKVQLKRPKNDK 310

 Score = 45.4 bits (106), Expect = 6e-05,   Method: Compositional matrix adjust.
 Identities = 24/61 (39%), Positives = 37/61 (60%), Gaps = 1/61 (1%)
 Frame = +2

Query: 204 DERLKELFGKFGPALSVKVMTD-ESGKSKGFGFVSFERHEDAQKAVDEMNGKELNGKQIY 262
           D+ L ++F  FG  +S KV  D ++  SK FGFVS++    AQ A+  MNG ++  K++ 
Sbjct: 101 DQDLMQMFMPFGNVISAKVFIDKQTNLSKCFGFVSYDSPMSAQDAISSMNGFQIGMKRLK 280

Query: 263 V 263
           V
Sbjct: 281 V 283

 Score = 43.5 bits (101), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 27/93 (29%), Positives = 50/93 (53%), Gaps = 8/93 (8%)
 Frame = +2

Query: 110 IDNKALYDTFSAFGNILSCKVVCDE--NGSKGYGFVHFETQEAAERAIEKMNGMLLNDRK 167
           + ++ L   F  FGN++S KV  D+  N SK +GFV +++  +A+ AI  MNG  +  ++
Sbjct: 95  VGDQDLMQMFMPFGNVISAKVFIDKQTNLSKCFGFVSYDSPMSAQDAISSMNGFQIGMKR 274

Query: 168 VFVGRFKSRKERE------AELGARAKEFTNVY 194
           + V   + + ++       A LG+ + + T  Y
Sbjct: 275 LKVQLKRPKNDKPY*TSCLAXLGSASSDDTMAY 373
>01278
          Length = 1082

 Score = 53.9 bits (128), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 26/69 (37%), Positives = 41/69 (59%), Gaps = 1/69 (1%)
 Frame = +2

Query: 186 RAKEFTNVYIKNFGEDMDDERLKELFGKFGPALSVKVMTDE-SGKSKGFGFVSFERHEDA 244
           R  E   + + N  ED  +  L+ELF  FGP   + +  D+ +G+SKGF F++F R EDA
Sbjct: 620 RKDEAATIRVTNLSEDTRESDLQELFRPFGPISRIYLAKDKVTGQSKGFAFINFHRREDA 799

Query: 245 QKAVDEMNG 253
            +A+  ++G
Sbjct: 800 SRAIAGVSG 826

 Score = 51.6 bits (122), Expect = 9e-07,   Method: Compositional matrix adjust.
 Identities = 24/59 (40%), Positives = 37/59 (62%)
 Frame = +2

Query: 11  ASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQPADAERAL 69
           A++ V +L  D  E+ L E F P GPI  I + +D +T +S G+A++NF +  DA RA+
Sbjct: 635 ATIRVTNLSEDTRESDLQELFRPFGPISRIYLAKDKVTGQSKGFAFINFHRREDASRAI 811

 Score = 35.8 bits (81), Expect = 0.049,   Method: Compositional matrix adjust.
 Identities = 22/70 (31%), Positives = 33/70 (47%), Gaps = 2/70 (2%)
 Frame = +2

Query: 94  RKSGVGNIFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDE--NGSKGYGFVHFETQEAA 151
           RK     I + NL +      L + F  FG I    +  D+    SKG+ F++F  +E A
Sbjct: 620 RKDEAATIRVTNLSEDTRESDLQELFRPFGPISRIYLAKDKVTGQSKGFAFINFHRREDA 799

Query: 152 ERAIEKMNGM 161
            RAI  ++G 
Sbjct: 800 SRAIAGVSGF 829
>02140
          Length = 1796

 Score = 53.5 bits (127), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 30/80 (37%), Positives = 43/80 (53%)
 Frame = +3

Query: 9   PMASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQPADAERA 68
           P   L+V  L+P  T+  L   FS  GPI S  V RD  T+ SL YA+V F++P   E A
Sbjct: 795 PDNVLFVCKLNPVTTDEDLEMIFSRFGPITSCEVIRDHKTKESLQYAFVEFEKPEHCENA 974

Query: 69  LDTMNFDVIKGKPVRIMWSQ 88
              M+  +I  + + + +SQ
Sbjct: 975 YFKMDNVLIDDRRIHVDFSQ 1034

 Score = 49.3 bits (116), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 26/72 (36%), Positives = 40/72 (55%), Gaps = 2/72 (2%)
 Frame = +3

Query: 101 IFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENGSKG--YGFVHFETQEAAERAIEKM 158
           +F+  L+    ++ L   FS FG I SC+V+ D    +   Y FV FE  E  E A  KM
Sbjct: 807 LFVCKLNPVTTDEDLEMIFSRFGPITSCEVIRDHKTKESLQYAFVEFEKPEHCENAYFKM 986

Query: 159 NGMLLNDRKVFV 170
           + +L++DR++ V
Sbjct: 987 DNVLIDDRRIHV 1022
>31310
          Length = 469

 Score = 53.5 bits (127), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 26/74 (35%), Positives = 45/74 (60%), Gaps = 1/74 (1%)
 Frame = -3

Query: 193 VYIKNFGEDMDDERLKELFGKFGPALSVKVMTDE-SGKSKGFGFVSFERHEDAQKAVDEM 251
           +Y+ +   ++ ++ +K+ F  FGP  SV +  D  + K KGF F+ ++  E AQ A+++M
Sbjct: 317 IYVGSINFEIREDTIKQAFLPFGPIKSVNLSWDPITNKHKGFSFIEYDVPEAAQLALEQM 138

Query: 252 NGKELNGKQIYVGR 265
           NG  + G+ I VGR
Sbjct: 137 NGVMIGGRNIKVGR 96

 Score = 53.1 bits (126), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 23/75 (30%), Positives = 45/75 (60%)
 Frame = -3

Query: 10  MASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQPADAERAL 69
           M  +YVG ++ ++ E  + + F P GPI S+ +  D IT +  G++++ +  P  A+ AL
Sbjct: 326 MCRIYVGSINFEIREDTIKQAFLPFGPIKSVNLSWDPITNKHKGFSFIEYDVPEAAQLAL 147

Query: 70  DTMNFDVIKGKPVRI 84
           + MN  +I G+ +++
Sbjct: 146 EQMNGVMIGGRNIKV 102

 Score = 49.7 bits (117), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 28/100 (28%), Positives = 52/100 (52%), Gaps = 5/100 (5%)
 Frame = -3

Query: 101 IFIKNLDKSIDNKALYDTFSAFGNILSCKVVCD--ENGSKGYGFVHFETQEAAERAIEKM 158
           I++ +++  I    +   F  FG I S  +  D   N  KG+ F+ ++  EAA+ A+E+M
Sbjct: 317 IYVGSINFEIREDTIKQAFLPFGPIKSVNLSWDPITNKHKGFSFIEYDVPEAAQLALEQM 138

Query: 159 NGMLLNDRKVFVGRFKSRKERE---AELGARAKEFTNVYI 195
           NG+++  R + VGR  +  + +    +L   A  +  +YI
Sbjct: 137 NGVMIGGRNIKVGRPSNMPQAQPIIEQLAMEATHYFRIYI 18

 Score = 43.9 bits (102), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 21/72 (29%), Positives = 41/72 (56%), Gaps = 2/72 (2%)
 Frame = -3

Query: 296 LYVKNLDDGIDDERLRKEFSPFGTITSAKVMME--GGRSKGFGFVCFSSPEEATKAVTEM 353
           +YV +++  I ++ +++ F PFG I S  +  +    + KGF F+ +  PE A  A+ +M
Sbjct: 317 IYVGSINFEIREDTIKQAFLPFGPIKSVNLSWDPITNKHKGFSFIEYDVPEAAQLALEQM 138

Query: 354 NGRIVATKPLYV 365
           NG ++  + + V
Sbjct: 137 NGVMIGGRNIKV 102
>14637
          Length = 455

 Score = 52.8 bits (125), Expect = 4e-07,   Method: Compositional matrix adjust.
 Identities = 30/81 (37%), Positives = 44/81 (54%), Gaps = 6/81 (7%)
 Frame = -1

Query: 281 EQMKQDRITRYQ----GVNLYVKNLDDGIDDERLRKEFSPFGTITSAKVMME--GGRSKG 334
            QM+Q+   +      G NL++ +L     D+ L + F PFG + SAKV ++     SK 
Sbjct: 254 NQMQQNAAAKQSEGPDGSNLFIYHLPQEFGDQDLMQMFMPFGNVISAKVFIDKQTNLSKC 75

Query: 335 FGFVCFSSPEEATKAVTEMNG 355
           FGFV + SP  A  A++ MNG
Sbjct: 74  FGFVSYDSPMSAQDAISSMNG 12

 Score = 48.1 bits (113), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 26/66 (39%), Positives = 40/66 (60%), Gaps = 2/66 (3%)
 Frame = -1

Query: 100 NIFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDE--NGSKGYGFVHFETQEAAERAIEK 157
           N+FI +L +   ++ L   F  FGN++S KV  D+  N SK +GFV +++  +A+ AI  
Sbjct: 200 NLFIYHLPQEFGDQDLMQMFMPFGNVISAKVFIDKQTNLSKCFGFVSYDSPMSAQDAISS 21

Query: 158 MNGMLL 163
           MNG  L
Sbjct: 20  MNGFRL 3

 Score = 48.1 bits (113), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 25/67 (37%), Positives = 40/67 (59%), Gaps = 1/67 (1%)
 Frame = -1

Query: 191 TNVYIKNFGEDMDDERLKELFGKFGPALSVKVMTD-ESGKSKGFGFVSFERHEDAQKAVD 249
           +N++I +  ++  D+ L ++F  FG  +S KV  D ++  SK FGFVS++    AQ A+ 
Sbjct: 203 SNLFIYHLPQEFGDQDLMQMFMPFGNVISAKVFIDKQTNLSKCFGFVSYDSPMSAQDAIS 24

Query: 250 EMNGKEL 256
            MNG  L
Sbjct: 23  SMNGFRL 3
>19868
          Length = 434

 Score = 50.8 bits (120), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 41/144 (28%), Positives = 65/144 (45%), Gaps = 7/144 (4%)
 Frame = +2

Query: 205 ERLKELFGKFGPALSVKVMTD-ESGKSKGFGFVSFERHEDAQK----AVDEMNGKELNGK 259
           E L++ F KFG    V VM D  + +S+GFGF++F       K    A  E++GK+++ K
Sbjct: 41  ESLRDYFNKFGEITEVMVMKDPTTRRSRGFGFITFGDPASVDKVLAQATHELDGKKIDPK 220

Query: 260 QIYVGRAQKKVERQTELKRKFEQMKQDRITRYQGVNLYVKNLDDGIDDERLRKEFSPFGT 319
             +  RA  ++  +T+                    ++V  L      E ++  F  FG 
Sbjct: 221 VAFPRRAHPRMVTRTK-------------------KIFVGGLSAPTTLEDVKNYFEQFGP 343

Query: 320 ITSAKVMME--GGRSKGFGFVCFS 341
           I  A +M +    R +GFGFV  S
Sbjct: 344 IEDAMLMFDKQTNRHRGFGFVTIS 415

 Score = 49.7 bits (117), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 34/135 (25%), Positives = 63/135 (46%), Gaps = 4/135 (2%)
 Frame = +2

Query: 13  LYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQPADAERALDTM 72
           ++VG L    +   L + F+  G I  + V +D  TRRS G+ ++ F  PA  ++ L   
Sbjct: 5   MFVGGLSWQTSPESLRDYFNKFGEITEVMVMKDPTTRRSRGFGFITFGDPASVDKVLAQA 184

Query: 73  NFDVIKGKPV--RIMWSQRDPSLRKSGVGNIFIKNLDKSIDNKALYDTFSAFGNILSCKV 130
             + + GK +  ++ + +R      +    IF+  L      + + + F  FG I    +
Sbjct: 185 THE-LDGKKIDPKVAFPRRAHPRMVTRTKKIFVGGLSAPTTLEDVKNYFEQFGPIEDAML 361

Query: 131 VCDE--NGSKGYGFV 143
           + D+  N  +G+GFV
Sbjct: 362 MFDKQTNRHRGFGFV 406

 Score = 42.0 bits (97), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 40/145 (27%), Positives = 58/145 (40%), Gaps = 6/145 (4%)
 Frame = +2

Query: 296 LYVKNLDDGIDDERLRKEFSPFGTITSAKVMME--GGRSKGFGFVCFSSPEEATK----A 349
           ++V  L      E LR  F+ FG IT   VM +    RS+GFGF+ F  P    K    A
Sbjct: 5   MFVGGLSWQTSPESLRDYFNKFGEITEVMVMKDPTTRRSRGFGFITFGDPASVDKVLAQA 184

Query: 350 VTEMNGRIVATKPLYVALAQRKEERQAHLTNQYMQRMASVRAVPNPVINPYQPAPPSGYF 409
             E++G+ +  K   VA  +R   R    T +      S       V N ++   P    
Sbjct: 185 THELDGKKIDPK---VAFPRRAHPRMVTRTKKIFVGGLSAPTTLEDVKNYFEQFGPIEDA 355

Query: 410 MAAIPQTQNRAAYYPPSQIAQLRPS 434
           M    +  NR   +    I++ R S
Sbjct: 356 MLMFDKQTNRHRGFGFVTISKRRHS 430
>23322
          Length = 471

 Score = 49.3 bits (116), Expect = 4e-06,   Method: Composition-based stats.
 Identities = 26/78 (33%), Positives = 48/78 (61%), Gaps = 1/78 (1%)
 Frame = -2

Query: 193 VYIKNFGEDMDDERLKELFGKFGPALSVKVMTDE-SGKSKGFGFVSFERHEDAQKAVDEM 251
           +++    ED  ++ +++ F +FG    V ++ D+ +GK++GF FV+F  H+   KAV + 
Sbjct: 404 MFVGGVKEDTTEDMIRDTFNEFGEITGVDLIQDKGTGKNRGFCFVTFGDHDSVDKAVLKK 225

Query: 252 NGKELNGKQIYVGRAQKK 269
              +LNG+Q+ V +AQ K
Sbjct: 224 R-HDLNGRQVEVKKAQSK 174

 Score = 36.2 bits (82), Expect = 0.036,   Method: Composition-based stats.
 Identities = 26/92 (28%), Positives = 45/92 (48%), Gaps = 7/92 (7%)
 Frame = -2

Query: 277 KRKFEQMKQDRITRYQGVN-LYVKNLDDGIDDERLRKEFSPFGTITSAKVMMEGG--RSK 333
           KR   + +  R    Q V  ++V  + +   ++ +R  F+ FG IT   ++ + G  +++
Sbjct: 464 KRAMPREESGRSEVQQSVKKMFVGGVKEDTTEDMIRDTFNEFGEITGVDLIQDKGTGKNR 285

Query: 334 GFGFVCFSSPEEATKAVT----EMNGRIVATK 361
           GF FV F   +   KAV     ++NGR V  K
Sbjct: 284 GFCFVTFGDHDSVDKAVLKKRHDLNGRQVEVK 189
>02415
          Length = 2763

 Score = 49.3 bits (116), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 25/86 (29%), Positives = 44/86 (51%), Gaps = 5/86 (5%)
 Frame = -1

Query: 184  GARAKEFTNVYIKNFGEDMDDERLKELFGKFGPALSVKVMTD-ESGKSKGFGFVSFERHE 242
            G +   +T +++        D  L+E F KFG      V+TD ++GKS+G+GFV+     
Sbjct: 1947 GQKDTTYTKIFVGGLPYHTTDHSLREYFDKFGDIDEAVVITDRQTGKSRGYGFVTMADRT 1768

Query: 243  DAQKAVDE----MNGKELNGKQIYVG 264
             A +A  +    ++G++ N    Y+G
Sbjct: 1767 GADRACKDPNPIIDGRKANVNLAYIG 1690

 Score = 38.9 bits (89), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 27/89 (30%), Positives = 45/89 (50%), Gaps = 2/89 (2%)
 Frame = -1

Query: 84   IMWSQRDPSLRKSGVGNIFIKNLDKSIDNKALYDTFSAFGNILSCKVVCD-ENG-SKGYG 141
            ++  Q+D +  K     IF+  L     + +L + F  FG+I    V+ D + G S+GYG
Sbjct: 1956 LITGQKDTTYTK-----IFVGGLPYHTTDHSLREYFDKFGDIDEAVVITDRQTGKSRGYG 1792

Query: 142  FVHFETQEAAERAIEKMNGMLLNDRKVFV 170
            FV    +  A+RA +  N  +++ RK  V
Sbjct: 1791 FVTMADRTGADRACKDPN-PIIDGRKANV 1708

 Score = 28.9 bits (63), Expect = 6.3,   Method: Compositional matrix adjust.
 Identities = 22/72 (30%), Positives = 31/72 (43%)
 Frame = -1

Query: 13   LYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQPADAERALDTM 72
            ++VG L    T+  L E F   G I    V  D  T +S GY +V       A+RA    
Sbjct: 1920 IFVGGLPYHTTDHSLREYFDKFGDIDEAVVITDRQTGKSRGYGFVTMADRTGADRACKDP 1741

Query: 73   NFDVIKGKPVRI 84
            N  +I G+   +
Sbjct: 1740 N-PIIDGRKANV 1708
>12506
          Length = 1056

 Score = 48.9 bits (115), Expect = 6e-06,   Method: Compositional matrix adjust.
 Identities = 27/68 (39%), Positives = 40/68 (58%), Gaps = 1/68 (1%)
 Frame = -3

Query: 201  DMDDERLKELFGKFGPALSVKVMTD-ESGKSKGFGFVSFERHEDAQKAVDEMNGKELNGK 259
            ++DD+ L   F  FG  + +++  D E+ K +GF F+ FE  EDA  A+D MN  EL G+
Sbjct: 1033 EVDDKVLHAAFLPFGDIVDIQIPLDYETEKHRGFAFIEFELAEDAAAAIDNMNESELFGR 854

Query: 260  QIYVGRAQ 267
             I V  A+
Sbjct: 853  TIRVNLAK 830

 Score = 38.9 bits (89), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 21/67 (31%), Positives = 35/67 (52%), Gaps = 2/67 (2%)
 Frame = -3

Query: 305  IDDERLRKEFSPFGTITSAKVMM--EGGRSKGFGFVCFSSPEEATKAVTEMNGRIVATKP 362
            +DD+ L   F PFG I   ++ +  E  + +GF F+ F   E+A  A+  MN   +  + 
Sbjct: 1030 VDDKVLHAAFLPFGDIVDIQIPLDYETEKHRGFAFIEFELAEDAAAAIDNMNESELFGRT 851

Query: 363  LYVALAQ 369
            + V LA+
Sbjct: 850  IRVNLAK 830
>20169
          Length = 1364

 Score = 48.9 bits (115), Expect = 7e-06,   Method: Compositional matrix adjust.
 Identities = 26/82 (31%), Positives = 44/82 (53%), Gaps = 3/82 (3%)
 Frame = -1

Query: 185  ARAKEFT---NVYIKNFGEDMDDERLKELFGKFGPALSVKVMTDESGKSKGFGFVSFERH 241
            +R ++F+    VY+   G     + L++ F K+GP  +V V      +  GF FV FE +
Sbjct: 1097 SRHRDFSLDCKVYVGELGHGCAKQELEDKFAKYGPLKNVWVAR----RPAGFAFVEFEDN 930

Query: 242  EDAQKAVDEMNGKELNGKQIYV 263
             DA+ AV  ++G  +NG++  V
Sbjct: 929  RDAEDAVQALDGARINGRRARV 864

 Score = 43.1 bits (100), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 23/77 (29%), Positives = 40/77 (51%)
 Frame = -1

Query: 11   ASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQPADAERALD 70
              +YVG+L     +  L +KF+  GP+ ++      + RR  G+A+V F+   DAE A+ 
Sbjct: 1070 CKVYVGELGHGCAKQELEDKFAKYGPLKNV-----WVARRPAGFAFVEFEDNRDAEDAVQ 906

Query: 71   TMNFDVIKGKPVRIMWS 87
             ++   I G+  R+  S
Sbjct: 905  ALDGARINGRRARVEMS 855
>13457
          Length = 4857

 Score = 35.0 bits (79), Expect(2) = 8e-06,   Method: Compositional matrix adjust.
 Identities = 14/37 (37%), Positives = 22/37 (59%)
 Frame = -3

Query: 292  QGVNLYVKNLDDGIDDERLRKEFSPFGTITSAKVMME 328
            +G NL++ +L     D  L + F PFG + SAKV ++
Sbjct: 2428 EGCNLFIYHLPQXXGDAELAQMFVPFGNVISAKVYVD 2318

 Score = 32.7 bits (73), Expect(2) = 8e-06,   Method: Compositional matrix adjust.
 Identities = 16/43 (37%), Positives = 23/43 (53%)
 Frame = -2

Query: 335  FGFVCFSSPEEATKAVTEMNGRIVATKPLYVALAQRKEERQAH 377
            FGFV F +P  A  A+  MNG  +  K L V L + K+  + +
Sbjct: 2294 FGFVSFDNPASAQAAIQAMNGFQIGMKRLKVQLKRPKDANRPY 2166

 Score = 30.8 bits (68), Expect(2) = 0.005,   Method: Compositional matrix adjust.
 Identities = 17/44 (38%), Positives = 23/44 (52%), Gaps = 2/44 (4%)
 Frame = -3

Query: 100  NIFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDE--NGSKGYG 141
            N+FI +L +   +  L   F  FGN++S KV  D   N SK  G
Sbjct: 2419 NLFIYHLPQXXGDAELAQMFVPFGNVISAKVYVDRATNQSKCLG 2288

 Score = 27.3 bits (59), Expect(2) = 0.005,   Method: Compositional matrix adjust.
 Identities = 10/29 (34%), Positives = 19/29 (65%)
 Frame = -2

Query: 140  YGFVHFETQEAAERAIEKMNGMLLNDRKV 168
            +GFV F+   +A+ AI+ MNG  +  +++
Sbjct: 2294 FGFVSFDNPASAQAAIQAMNGFQIGMKRL 2208

 Score = 31.2 bits (69), Expect = 1.4,   Method: Compositional matrix adjust.
 Identities = 14/31 (45%), Positives = 20/31 (64%)
 Frame = -2

Query: 233  FGFVSFERHEDAQKAVDEMNGKELNGKQIYV 263
            FGFVSF+    AQ A+  MNG ++  K++ V
Sbjct: 2294 FGFVSFDNPASAQAAIQAMNGFQIGMKRLKV 2202
>11019
          Length = 552

 Score = 48.1 bits (113), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 45/171 (26%), Positives = 73/171 (42%), Gaps = 14/171 (8%)
 Frame = -1

Query: 205 ERLKELFGKFGPALSVKVMTDESGK-SKGFGFVSFERHEDAQKAVDE----MNGKELNGK 259
           E L+  F KFG      VM D + K S+GFGFV+++   +    +      ++ K LN  
Sbjct: 522 ETLRSYFEKFGEIKESMVMKDPTSKRSRGFGFVTYKDPSNVDNVLANGPHCIDSKTLNFS 343

Query: 260 QI---YVGRAQKKVERQTELKRKFEQMKQDRITRYQGVNLYVKNLDDGIDDERLRKEFSP 316
            +   Y  +       Q + K  F +    R+   +   ++V  L      E ++  F  
Sbjct: 342 NMTTFYSNQDLLPYPPQVDPKVAFPRKSNPRMVT-KTKKIFVGGLSSSTTVEDIKNYFKA 166

Query: 317 FGTITSAKVMME--GGRSKGFGFVCFSSPEEATKAVT----EMNGRIVATK 361
           +GTI  A +M +    R +GF FV F +     K       E+N ++V TK
Sbjct: 165 YGTIEEATLMFDKVTSRHRGFAFVTFDNESTVDKVCEIHFHEINSKMVETK 13

 Score = 43.9 bits (102), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 41/172 (23%), Positives = 70/172 (40%), Gaps = 30/172 (17%)
 Frame = -1

Query: 15  VGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQPADAERAL----- 69
           +G L    T   L   F   G I    V +D  ++RS G+ +V ++ P++ +  L     
Sbjct: 552 IGGLSWQTTTETLRSYFEKFGEIKESMVMKDPTSKRSRGFGFVTYKDPSNVDNVLANGPH 373

Query: 70  ----DTMNF----------DVIKGKPVRIMWSQRDPSL---RKSG------VGNIFIKNL 106
                T+NF          D++   P      Q DP +   RKS          IF+  L
Sbjct: 372 CIDSKTLNFSNMTTFYSNQDLLPYPP------QVDPKVAFPRKSNPRMVTKTKKIFVGGL 211

Query: 107 DKSIDNKALYDTFSAFGNILSCKVVCDENGS--KGYGFVHFETQEAAERAIE 156
             S   + + + F A+G I    ++ D+  S  +G+ FV F+ +   ++  E
Sbjct: 210 SSSTTVEDIKNYFKAYGTIEEATLMFDKVTSRHRGFAFVTFDNESTVDKVCE 55

 Score = 30.4 bits (67), Expect = 2.2,   Method: Compositional matrix adjust.
 Identities = 19/76 (25%), Positives = 33/76 (43%)
 Frame = -1

Query: 13  LYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQPADAERALDTM 72
           ++VG L    T   +   F   G I    +  D +T R  G+A+V F   +  ++  + +
Sbjct: 228 IFVGGLSSSTTVEDIKNYFKAYGTIEEATLMFDKVTSRHRGFAFVTFDNESTVDKVCE-I 52

Query: 73  NFDVIKGKPVRIMWSQ 88
           +F  I  K V    +Q
Sbjct: 51  HFHEINSKMVETKKAQ 4
>12350
          Length = 975

 Score = 47.8 bits (112), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 40/150 (26%), Positives = 66/150 (44%), Gaps = 1/150 (0%)
 Frame = -2

Query: 204 DERLKELFGKFGPALSVKVMTD-ESGKSKGFGFVSFERHEDAQKAVDEMNGKELNGKQIY 262
           ++ L+  F +FG  L V+V  D ++G+SKGFGF+ F  +E   K + + +   ++G+   
Sbjct: 581 EDDLRSYFSQFGDLLMVQVKKDPKTGQSKGFGFIRFAEYESQLKCMAQRH--MIDGRWCD 408

Query: 263 VGRAQKKVERQTELKRKFEQMKQDRITRYQGVNLYVKNLDDGIDDERLRKEFSPFGTITS 322
           V     K   Q  + RK                ++V    D +  + LR+ FS FG +  
Sbjct: 407 VRIPNSKEGAQQLMNRK----------------IFVGRCTDDMTADDLRQFFSKFGEVVD 276

Query: 323 AKVMMEGGRSKGFGFVCFSSPEEATKAVTE 352
             +       + F FV F+ PE A     E
Sbjct: 275 VFIPRP---FRAFAFVSFADPEVAQSLYGE 195

 Score = 45.4 bits (106), Expect = 6e-05,   Method: Compositional matrix adjust.
 Identities = 43/162 (26%), Positives = 74/162 (45%), Gaps = 3/162 (1%)
 Frame = -2

Query: 115 LYDTFSAFGNILSCKVVCD--ENGSKGYGFVHFETQEAAERAIEKMNGMLLNDRKVFVGR 172
           L   FS FG++L  +V  D     SKG+GF+ F   E+  + + +        R +  GR
Sbjct: 572 LRSYFSQFGDLLMVQVKKDPKTGQSKGFGFIRFAEYESQLKCMAQ--------RHMIDGR 417

Query: 173 FKSRKEREAELGARAKEFTNVYIKNFGEDMDDERLKELFGKFGPALSVKVMTDESGKSKG 232
           +   +   ++ GA+      +++    +DM  + L++ F KFG  + V +        + 
Sbjct: 416 WCDVRIPNSKEGAQQLMNRKIFVGRCTDDMTADDLRQFFSKFGEVVDVFIPR----PFRA 249

Query: 233 FGFVSFERHEDAQKAVDEMNGKELNGKQIYV-GRAQKKVERQ 273
           F FVSF   E AQ    E +   + G  +++ G A K  E+Q
Sbjct: 248 FAFVSFADPEVAQSLYGEDH--IIKGASVHISGAAPKPNEKQ 129

 Score = 32.7 bits (73), Expect = 0.42,   Method: Compositional matrix adjust.
 Identities = 23/78 (29%), Positives = 39/78 (50%), Gaps = 5/78 (6%)
 Frame = -2

Query: 289 TRYQGVNLYVKNLDDGIDDERLRKEFSPFGTITSAKVMME--GGRSKGFGFVCFSSPEEA 346
           +R +  +L V  L     ++ LR  FS FG +   +V  +   G+SKGFGF+ F+  E  
Sbjct: 635 SRQKCSDLIVLGLPWKSTEDDLRSYFSQFGDLLMVQVKKDPKTGQSKGFGFIRFAEYESQ 456

Query: 347 TKAVTE---MNGRIVATK 361
            K + +   ++GR    +
Sbjct: 455 LKCMAQRHMIDGRWCDVR 402
>02502
          Length = 1557

 Score = 47.8 bits (112), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 29/117 (24%), Positives = 54/117 (46%), Gaps = 18/117 (15%)
 Frame = -3

Query: 80   KPVRIMWSQRDP-------SLRKSGVGNIF-----------IKNLDKSIDNKALYDTFSA 121
            +P+R  W+ R P       S+R+     +F              ++  +  + +++TF  
Sbjct: 1552 RPIRTNWATRKPLAPIAKDSVRQLSYDEVFNQSSQTNCTVYCGGVNNGLTEELMHNTFKD 1373

Query: 122  FGNILSCKVVCDENGSKGYGFVHFETQEAAERAIEKMNGMLLNDRKVFVGRFKSRKE 178
            FG+IL  ++  D    KG+ F+ F  ++AA  AI  ++G ++ND+ V     K   E
Sbjct: 1372 FGSILEVRIFKD----KGFAFIRFNNKDAATNAICTIHGTVINDQVVRCSWGKESNE 1214
>28455
          Length = 573

 Score = 47.4 bits (111), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 24/72 (33%), Positives = 40/72 (55%), Gaps = 1/72 (1%)
 Frame = -1

Query: 101 IFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENG-SKGYGFVHFETQEAAERAIEKMN 159
           +F+KNL  +   +AL   F   G +   ++V   +G SKG  +V FET+E A +A+ K +
Sbjct: 534 LFVKNLPFTCSAEALETIFKEHGKVKDVRLVTYRSGASKGLAYVEFETEEMATQAVMKTD 355

Query: 160 GMLLNDRKVFVG 171
           G+ + D  + V 
Sbjct: 354 GLQVGDHMISVA 319

 Score = 43.9 bits (102), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 25/80 (31%), Positives = 41/80 (51%)
 Frame = -1

Query: 185 ARAKEFTNVYIKNFGEDMDDERLKELFGKFGPALSVKVMTDESGKSKGFGFVSFERHEDA 244
           A + E   +++KN       E L+ +F + G    V+++T  SG SKG  +V FE  E A
Sbjct: 558 ATSLEKNKLFVKNLPFTCSAEALETIFKEHGKVKDVRLVTYRSGASKGLAYVEFETEEMA 379

Query: 245 QKAVDEMNGKELNGKQIYVG 264
            +AV + +G ++    I V 
Sbjct: 378 TQAVMKTDGLQVGDHMISVA 319
>02064
          Length = 1195

 Score = 47.0 bits (110), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 29/89 (32%), Positives = 47/89 (52%), Gaps = 5/89 (5%)
 Frame = +1

Query: 287 RITRYQGVNLYVKNLDDGIDDERLRKEFSPFGTITSAKVMMEGGRSKGFGFVCFSSPEEA 346
           R+TR     + VKNL   I  + LR+ F   G +  +++ M+ GRS G G V F++ ++A
Sbjct: 58  RVTRPDNCTVQVKNLPYAITWQDLRERFQEIGVVKYSEITMDKGRSTGQGLVRFATEDDA 237

Query: 347 TKAVTEMN-----GRIVATKPLYVALAQR 370
            +A+  M+     GR +  K +Y    QR
Sbjct: 238 VRAINSMDRTRYEGRTIGVK-MYRG*WQR 321
>00029
          Length = 2204

 Score = 47.0 bits (110), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 23/71 (32%), Positives = 37/71 (52%)
 Frame = -3

Query: 193  VYIKNFGEDMDDERLKELFGKFGPALSVKVMTDESGKSKGFGFVSFERHEDAQKAVDEMN 252
            ++I N G+D D E L+ LF K+G      V+       K FGFV   +  +A  A+  +N
Sbjct: 2130 IFIGNLGDDTDPEELRALFEKYGSVAECDVL-------KNFGFVHMVKKGEADDAISNLN 1972

Query: 253  GKELNGKQIYV 263
            G  + G+++ V
Sbjct: 1971 GYNIGGQRMRV 1939

 Score = 43.5 bits (101), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 22/70 (31%), Positives = 35/70 (50%)
 Frame = -3

Query: 101  IFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENGSKGYGFVHFETQEAAERAIEKMNG 160
            IFI NL    D + L   F  +G++  C V+      K +GFVH   +  A+ AI  +NG
Sbjct: 2130 IFIGNLGDDTDPEELRALFEKYGSVAECDVL------KNFGFVHMVKKGEADDAISNLNG 1969

Query: 161  MLLNDRKVFV 170
              +  +++ V
Sbjct: 1968 YNIGGQRMRV 1939

 Score = 42.7 bits (99), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 22/75 (29%), Positives = 37/75 (49%)
 Frame = -3

Query: 294  VNLYVKNLDDGIDDERLRKEFSPFGTITSAKVMMEGGRSKGFGFVCFSSPEEATKAVTEM 353
            + +++ NL D  D E LR  F  +G++    V+      K FGFV      EA  A++ +
Sbjct: 2136 IKIFIGNLGDDTDPEELRALFEKYGSVAECDVL------KNFGFVHMVKKGEADDAISNL 1975

Query: 354  NGRIVATKPLYVALA 368
            NG  +  + + V L+
Sbjct: 1974 NGYNIGGQRMRVELS 1930
>28605
          Length = 697

 Score = 47.0 bits (110), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 25/69 (36%), Positives = 38/69 (55%), Gaps = 1/69 (1%)
 Frame = -3

Query: 101 IFIKNLDKSIDNKA-LYDTFSAFGNILSCKVVCDENGSKGYGFVHFETQEAAERAIEKMN 159
           +F+ NL     ++A L + FS +GN+L   V  +      YGFV F T+E   RA+E MN
Sbjct: 563 VFVANLSSDETSEAELQELFSKYGNVLDTLVHHNR-----YGFVQFSTEEEGRRAVEAMN 399

Query: 160 GMLLNDRKV 168
           G +   +K+
Sbjct: 398 GYMFYRKKL 372

 Score = 38.9 bits (89), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 23/72 (31%), Positives = 36/72 (50%), Gaps = 1/72 (1%)
 Frame = -3

Query: 191 TNVYIKNFGEDMDDE-RLKELFGKFGPALSVKVMTDESGKSKGFGFVSFERHEDAQKAVD 249
           + V++ N   D   E  L+ELF K+G  L   V  +       +GFV F   E+ ++AV+
Sbjct: 569 SRVFVANLSSDETSEAELQELFSKYGNVLDTLVHHNR------YGFVQFSTEEEGRRAVE 408

Query: 250 EMNGKELNGKQI 261
            MNG     K++
Sbjct: 407 AMNGYMFYRKKL 372

 Score = 34.7 bits (78), Expect = 0.11,   Method: Compositional matrix adjust.
 Identities = 23/69 (33%), Positives = 34/69 (49%), Gaps = 1/69 (1%)
 Frame = -3

Query: 296 LYVKNLD-DGIDDERLRKEFSPFGTITSAKVMMEGGRSKGFGFVCFSSPEEATKAVTEMN 354
           ++V NL  D   +  L++ FS +G +    V         +GFV FS+ EE  +AV  MN
Sbjct: 563 VFVANLSSDETSEAELQELFSKYGNVLDTLV-----HHNRYGFVQFSTEEEGRRAVEAMN 399

Query: 355 GRIVATKPL 363
           G +   K L
Sbjct: 398 GYMFYRKKL 372
>03200
          Length = 657

 Score = 46.2 bits (108), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 25/80 (31%), Positives = 43/80 (53%)
 Frame = -1

Query: 292 QGVNLYVKNLDDGIDDERLRKEFSPFGTITSAKVMMEGGRSKGFGFVCFSSPEEATKAVT 351
           +G  +YV  +  G+ ++ L+  FS FG I +  +     R +  GFV F   E A +A+ 
Sbjct: 492 KGHTVYVHGI--GVTEDILKSAFSNFGNIVNINI----ERERNNGFVTFEKMESADQAIA 331

Query: 352 EMNGRIVATKPLYVALAQRK 371
            MNG +++   L V +A+R+
Sbjct: 330 NMNGSMISNVQLKVMMARRQ 271

 Score = 40.8 bits (94), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 23/60 (38%), Positives = 35/60 (58%), Gaps = 2/60 (3%)
 Frame = -1

Query: 115 LYDTFSAFGNILSCKVVCDENGSKGYGFVHFETQEAAERAIEKMNGMLLND--RKVFVGR 172
           L   FS FGNI++  +  + N     GFV FE  E+A++AI  MNG ++++   KV + R
Sbjct: 444 LKSAFSNFGNIVNINIERERNN----GFVTFEKMESADQAIANMNGSMISNVQLKVMMAR 277

 Score = 40.4 bits (93), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 22/77 (28%), Positives = 42/77 (54%)
 Frame = -1

Query: 193 VYIKNFGEDMDDERLKELFGKFGPALSVKVMTDESGKSKGFGFVSFERHEDAQKAVDEMN 252
           VY+   G  + ++ LK  F  FG  +++ +      + +  GFV+FE+ E A +A+  MN
Sbjct: 480 VYVHGIG--VTEDILKSAFSNFGNIVNINI-----ERERNNGFVTFEKMESADQAIANMN 322

Query: 253 GKELNGKQIYVGRAQKK 269
           G  ++  Q+ V  A+++
Sbjct: 321 GSMISNVQLKVMMARRQ 271
>03059
          Length = 1154

 Score = 44.7 bits (104), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 21/73 (28%), Positives = 42/73 (57%), Gaps = 2/73 (2%)
 Frame = -2

Query: 191 TNVYIKNFGEDMDDERLKELFGKFGPALSVKVMTD--ESGKSKGFGFVSFERHEDAQKAV 248
           T V++     +++ + ++E+F  +G    + +  D      SKG  +V +E  EDA+KAV
Sbjct: 670 TKVHVGRLTRNVNKDHIQEIFSLYGTIKFIDLPNDRIHPNTSKGHAYVEYENPEDAEKAV 491

Query: 249 DEMNGKELNGKQI 261
             M+G +++G++I
Sbjct: 490 KYMDGGQIDGQEI 452

 Score = 40.4 bits (93), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 26/79 (32%), Positives = 42/79 (53%), Gaps = 1/79 (1%)
 Frame = -2

Query: 5   APSYPMASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMIT-RRSLGYAYVNFQQPA 63
           +P+     ++VG L  +V +  + E FS  G I  I +  D I    S G+AYV ++ P 
Sbjct: 688 SPTPKPTKVHVGRLTRNVNKDHIQEIFSLYGTIKFIDLPNDRIHPNTSKGHAYVEYENPE 509

Query: 64  DAERALDTMNFDVIKGKPV 82
           DAE+A+  M+   I G+ +
Sbjct: 508 DAEKAVKYMDGGQIDGQEI 452

 Score = 35.0 bits (79), Expect = 0.089,   Method: Compositional matrix adjust.
 Identities = 19/65 (29%), Positives = 35/65 (53%), Gaps = 3/65 (4%)
 Frame = -2

Query: 294 VNLYVKNLDDGIDDERLRKEFSPFGTITSAKV---MMEGGRSKGFGFVCFSSPEEATKAV 350
             ++V  L   ++ + +++ FS +GTI    +    +    SKG  +V + +PE+A KAV
Sbjct: 670 TKVHVGRLTRNVNKDHIQEIFSLYGTIKFIDLPNDRIHPNTSKGHAYVEYENPEDAEKAV 491

Query: 351 TEMNG 355
             M+G
Sbjct: 490 KYMDG 476
>15371
          Length = 383

 Score = 43.9 bits (102), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 22/53 (41%), Positives = 31/53 (58%), Gaps = 2/53 (3%)
 Frame = -2

Query: 293 GVNLYVKNLDDGIDDERLRKEFSPFGTITSAKVMME--GGRSKGFGFVCFSSP 343
           G NL++ +L     D+ L + F PFG + SAKV ++     SK FGFV + SP
Sbjct: 160 GANLFIYHLPQEFGDQDLMQMFMPFGNVVSAKVFIDKQTNLSKCFGFVSYDSP 2

 Score = 37.7 bits (86), Expect = 0.016,   Method: Compositional matrix adjust.
 Identities = 19/50 (38%), Positives = 31/50 (62%), Gaps = 2/50 (4%)
 Frame = -2

Query: 100 NIFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDE--NGSKGYGFVHFET 147
           N+FI +L +   ++ L   F  FGN++S KV  D+  N SK +GFV +++
Sbjct: 154 NLFIYHLPQEFGDQDLMQMFMPFGNVVSAKVFIDKQTNLSKCFGFVSYDS 5
>02091
          Length = 2031

 Score = 43.5 bits (101), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 32/77 (41%), Positives = 45/77 (58%), Gaps = 1/77 (1%)
 Frame = -2

Query: 539  VQGQEPLTASMLASAPPQEQKQMLGERLFPLIQAMHPSLAGKITGMLLEIDNSELLH-ML 597
             QGQ    A+ +A A PQ Q QM+GE+LF L+   +P      T  +L+ DNSELL  ML
Sbjct: 1406 CQGQN--EAATVAEAHPQVQTQMIGEQLFSLMSDXYP----YPTDXMLKFDNSELLRIML 1245

Query: 598  ESPESLRSKVDEAVAVL 614
            E  +S+  + D A+ +L
Sbjct: 1244 ECQQSVNYR-DAAMVML 1197
>25746
          Length = 475

 Score = 43.5 bits (101), Expect = 3e-04,   Method: Composition-based stats.
 Identities = 23/85 (27%), Positives = 43/85 (50%), Gaps = 8/85 (9%)
 Frame = +1

Query: 191 TNVYIKNFGEDMDDERLKELFGKFGPAL--------SVKVMTDESGKSKGFGFVSFERHE 242
           T+VY+     D+ DE+ +EL  K+G  +         +K+  +  G  KG G   + + E
Sbjct: 73  THVYVSGLPSDLTDEQFQELMSKYGLIMFDPHTHKPKLKLYRNHDGTLKGDGLCCYIKQE 252

Query: 243 DAQKAVDEMNGKELNGKQIYVGRAQ 267
               A++ ++G +++G  I V RA+
Sbjct: 253 SVDLALNILDGSDVHGSTISVERAK 327
>35379
          Length = 534

 Score = 42.7 bits (99), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 25/60 (41%), Positives = 34/60 (56%), Gaps = 6/60 (10%)
 Frame = +1

Query: 118 TFSAFGNILSCK-----VVCDENGSKGYGFVHFETQEAAERAIEK-MNGMLLNDRKVFVG 171
            FSAFG +   K     + C     KGYGFV FE QE A+R I+K  + ++  DRK+ +G
Sbjct: 43  VFSAFGPVKDAK**QTELEC----PKGYGFVTFENQEDADRIIKKEADNLIFKDRKLNIG 210

 Score = 35.8 bits (81), Expect = 0.051,   Method: Compositional matrix adjust.
 Identities = 20/61 (32%), Positives = 31/61 (50%), Gaps = 1/61 (1%)
 Frame = +1

Query: 210 LFGKFGPALSVKVMTDESGKSKGFGFVSFERHEDAQKAV-DEMNGKELNGKQIYVGRAQK 268
           +F  FGP    K    E    KG+GFV+FE  EDA + +  E +      +++ +G A +
Sbjct: 43  VFSAFGPVKDAK**QTELECPKGYGFVTFENQEDADRIIKKEADNLIFKDRKLNIGPAVR 222

Query: 269 K 269
           K
Sbjct: 223 K 225

 Score = 30.8 bits (68), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 21/61 (34%), Positives = 31/61 (50%), Gaps = 2/61 (3%)
 Frame = +1

Query: 314 FSPFGTITSAKV-MMEGGRSKGFGFVCFSSPEEATKAV-TEMNGRIVATKPLYVALAQRK 371
           FS FG +  AK    E    KG+GFV F + E+A + +  E +  I   + L +  A RK
Sbjct: 46  FSAFGPVKDAK**QTELECPKGYGFVTFENQEDADRIIKKEADNLIFKDRKLNIGPAVRK 225

Query: 372 E 372
           +
Sbjct: 226 Q 228
>00556
          Length = 2189

 Score = 42.4 bits (98), Expect = 6e-04,   Method: Compositional matrix adjust.
 Identities = 22/75 (29%), Positives = 39/75 (52%), Gaps = 1/75 (1%)
 Frame = +3

Query: 193 VYIKNFGEDMDDERLKELFGKFGPALSVKVMTDE-SGKSKGFGFVSFERHEDAQKAVDEM 251
           +++      + ++++KEL   FGP  S  ++ D  +G SKGF F  +       +A   +
Sbjct: 765 IFMGGLPSYLSEDQMKELLLSFGPLKSFNLVRDNATGLSKGFAFCEYLDPSVTDQACAGL 944

Query: 252 NGKELNGKQIYVGRA 266
           NG +L  K++ V RA
Sbjct: 945 NGMQLGDKKLIVQRA 989

 Score = 38.1 bits (87), Expect = 0.011,   Method: Compositional matrix adjust.
 Identities = 45/197 (22%), Positives = 78/197 (39%), Gaps = 36/197 (18%)
 Frame = +3

Query: 101 IFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENG--SKGYGFVHFETQEAAERAIEKM 158
           IF+  L   +    + +   +FG + S  +V D     SKG+ F  +      ++A   +
Sbjct: 765 IFMGGLPSYLSEDQMKELLLSFGPLKSFNLVRDNATGLSKGFAFCEYLDPSVTDQACAGL 944

Query: 159 NGMLLNDRKVFVGRFKSRKEREAELGAR-AKEFTNVYIKNFGEDMDDE------------ 205
           NGM L D+K+ V R        A +GA+ A     V ++  G +++ E            
Sbjct: 945 NGMQLGDKKLIVQR--------ASIGAKGAMNQAPVQLQVPGLNLNQEIVQATEILCLMN 1100

Query: 206 ------------------RLKELFGKFGPALSVKVMTDESG-KSKGFG--FVSFERHEDA 244
                              +KE  GK+G   S+++     G +  G G  FV F    D 
Sbjct: 1101MIMPEELEDEEEYEDILEXVKEECGKYGSVRSLEIPRPIKGVEVPGVGKIFVEFNSILDC 1280

Query: 245 QKAVDEMNGKELNGKQI 261
           QKA   + G++ + + +
Sbjct: 1281QKAQQALAGRKFSSRVV 1331

 Score = 32.3 bits (72), Expect = 0.62,   Method: Compositional matrix adjust.
 Identities = 16/61 (26%), Positives = 31/61 (50%)
 Frame = +3

Query: 13  LYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQPADAERALDTM 72
           +++G L   ++E  + E     GP+ S  + RD  T  S G+A+  +  P+  ++A   +
Sbjct: 765 IFMGGLPSYLSEDQMKELLLSFGPLKSFNLVRDNATGLSKGFAFCEYLDPSVTDQACAGL 944

Query: 73  N 73
           N
Sbjct: 945 N 947

 Score = 30.4 bits (67), Expect = 2.0,   Method: Compositional matrix adjust.
 Identities = 17/72 (23%), Positives = 35/72 (48%), Gaps = 2/72 (2%)
 Frame = +3

Query: 296 LYVKNLDDGIDDERLRKEFSPFGTITSAKVMMEG--GRSKGFGFVCFSSPEEATKAVTEM 353
           +++  L   + ++++++    FG + S  ++ +   G SKGF F  +  P    +A   +
Sbjct: 765 IFMGGLPSYLSEDQMKELLLSFGPLKSFNLVRDNATGLSKGFAFCEYLDPSVTDQACAGL 944

Query: 354 NGRIVATKPLYV 365
           NG  +  K L V
Sbjct: 945 NGMQLGDKKLIV 980
>33516
          Length = 449

 Score = 42.0 bits (97), Expect = 7e-04,   Method: Composition-based stats.
 Identities = 23/72 (31%), Positives = 39/72 (54%), Gaps = 1/72 (1%)
 Frame = +1

Query: 169 FVGRFKSRKEREAELGARAKEFTNVYIKNFGEDMDDERLKELFGKFGPALSVKVMTDE-S 227
           F   F    +++  +G R +E   +++     D D + L+  F +FG      VM ++ +
Sbjct: 91  FAIYFGENSKKQFNMGGR-EEPGKIFVGGLSWDTDQDSLQGYFSQFGEITDCIVMMNQQT 267

Query: 228 GKSKGFGFVSFE 239
           GKS+GFGFVSF+
Sbjct: 268 GKSRGFGFVSFK 303

 Score = 42.0 bits (97), Expect = 8e-04,   Method: Composition-based stats.
 Identities = 22/50 (44%), Positives = 29/50 (58%), Gaps = 2/50 (4%)
 Frame = +1

Query: 296 LYVKNLDDGIDDERLRKEFSPFGTITSAKVMM--EGGRSKGFGFVCFSSP 343
           ++V  L    D + L+  FS FG IT   VMM  + G+S+GFGFV F  P
Sbjct: 160 IFVGGLSWDTDQDSLQGYFSQFGEITDCIVMMNQQTGKSRGFGFVSFKDP 309
>03903
          Length = 983

 Score = 42.0 bits (97), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 40/154 (25%), Positives = 69/154 (44%), Gaps = 13/154 (8%)
 Frame = -1

Query: 229 KSKGFGFVS--FERHEDAQKAVDEMNGKE---LNGKQIYVGRAQKKVERQTELKRKFEQM 283
           +S GFG ++   +  ED +   DE    E   ++  ++  GR   +   +  + R +++ 
Sbjct: 647 QSTGFGVLAPAAKXQEDHEANDDEEGWSETKFISRSELRKGRLSXREMEEISVFRNYKEG 468

Query: 284 KQDRITRYQGVNLYVKNLDDGIDDERLRKEFSPF--------GTITSAKVMMEGGRSKGF 335
           +  R        LY+KNL   + +E L   F  +         +I   ++M EG R KG 
Sbjct: 467 EPSR-------RLYIKNLSKQVTEEDLHWVFGRYVNWDKEEEKSIFDIRLMKEG-RMKGQ 312

Query: 336 GFVCFSSPEEATKAVTEMNGRIVATKPLYVALAQ 369
            FV   + E+A KAV + N  +   KP+ V  A+
Sbjct: 311 AFVTLGTEEQARKAVKDTNAFVFKGKPIAVHFAR 210

 Score = 37.0 bits (84), Expect = 0.022,   Method: Compositional matrix adjust.
 Identities = 24/79 (30%), Positives = 39/79 (49%), Gaps = 8/79 (10%)
 Frame = -1

Query: 193 VYIKNFGEDMDDERLKELFGKF--------GPALSVKVMTDESGKSKGFGFVSFERHEDA 244
           +YIKN  + + +E L  +FG++             +++M +  G+ KG  FV+    E A
Sbjct: 452 LYIKNLSKQVTEEDLHWVFGRYVNWDKEEEKSIFDIRLMKE--GRMKGQAFVTLGTEEQA 279

Query: 245 QKAVDEMNGKELNGKQIYV 263
           +KAV + N     GK I V
Sbjct: 278 RKAVKDTNAFVFKGKPIAV 222
>02347
          Length = 928

 Score = 42.0 bits (97), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 22/74 (29%), Positives = 39/74 (52%)
 Frame = -3

Query: 11  ASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQPADAERALD 70
             +YVGDL PD +E  +   F+  G + ++      + R   G+A+V F+   DA+ A+ 
Sbjct: 746 GKIYVGDLPPDASEKEVERAFNYYGHLRNV-----WVARNPPGFAFVEFEDTRDADDAVR 582

Query: 71  TMNFDVIKGKPVRI 84
            ++  V+ G  VR+
Sbjct: 581 ALDGTVVCGNRVRV 540
>29364
          Length = 1126

 Score = 41.2 bits (95), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 18/32 (56%), Positives = 24/32 (75%)
 Frame = +1

Query: 232 GFGFVSFERHEDAQKAVDEMNGKELNGKQIYV 263
           G+GFV FE + DA  AV E+NGKEL G+++ V
Sbjct: 70  GYGFVEFEDYRDADDAVYELNGKELLGERVVV 165

 Score = 29.6 bits (65), Expect = 3.9,   Method: Compositional matrix adjust.
 Identities = 14/32 (43%), Positives = 19/32 (59%)
 Frame = +1

Query: 139 GYGFVHFETQEAAERAIEKMNGMLLNDRKVFV 170
           GYGFV FE    A+ A+ ++NG  L   +V V
Sbjct: 70  GYGFVEFEDYRDADDAVYELNGKELLGERVVV 165
>32386
          Length = 674

 Score = 40.8 bits (94), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 26/103 (25%), Positives = 53/103 (51%), Gaps = 5/103 (4%)
 Frame = +1

Query: 183 LGARAKEFTNVYIKNFGEDMDDERLKELFGKFGPALSVKVMTDESGK-SKGFGFVSFERH 241
           L   A++F  ++I     + D++ L+  F  +G  +   VM D + K S+GFGF++++  
Sbjct: 277 LDPNAEQFRKLFIGGLSYETDEDSLRSHFETWGEIVDCIVMRDSNSKRSRGFGFITYKDA 456

Query: 242 EDAQKAV----DEMNGKELNGKQIYVGRAQKKVERQTELKRKF 280
           E   +A      +++G+E++ K+        + E Q  +K+ F
Sbjct: 457 ESIDQAQANRPHKIDGREVDTKRAMPREESGRSEVQQSVKKMF 585

 Score = 38.9 bits (89), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 23/72 (31%), Positives = 36/72 (50%), Gaps = 6/72 (8%)
 Frame = +1

Query: 296 LYVKNLDDGIDDERLRKEFSPFGTITSAKVMMEGG--RSKGFGFVCFSSPEEATKAVT-- 351
           L++  L    D++ LR  F  +G I    VM +    RS+GFGF+ +   E   +A    
Sbjct: 307 LFIGGLSYETDEDSLRSHFETWGEIVDCIVMRDSNSKRSRGFGFITYKDAESIDQAQANR 486

Query: 352 --EMNGRIVATK 361
             +++GR V TK
Sbjct: 487 PHKIDGREVDTK 522
>24983
          Length = 433

 Score = 40.4 bits (93), Expect = 0.002,   Method: Composition-based stats.
 Identities = 24/66 (36%), Positives = 36/66 (54%), Gaps = 5/66 (7%)
 Frame = -2

Query: 204 DERLKELFGKFGPALSVKVMTD-ESGKSKGFGFVSFERHEDAQKAVDEMN----GKELNG 258
           D  L+E F KFG      V+TD ++GKS+G+GFV+      A +A  + N    G++ N 
Sbjct: 276 DHSLREYFDKFGDIDEAVVITDRQTGKSRGYGFVTMADRTGADRACKDPNPIIDGRKANV 97

Query: 259 KQIYVG 264
              Y+G
Sbjct: 96  NLAYIG 79

 Score = 30.4 bits (67), Expect = 2.3,   Method: Composition-based stats.
 Identities = 17/53 (32%), Positives = 28/53 (52%), Gaps = 2/53 (3%)
 Frame = -2

Query: 112 NKALYDTFSAFGNILSCKVVCDEN--GSKGYGFVHFETQEAAERAIEKMNGML 162
           + +L + F  FG+I    V+ D     S+GYGFV    +  A+RA +  N ++
Sbjct: 276 DHSLREYFDKFGDIDEAVVITDRQTGKSRGYGFVTMADRTGADRACKDPNPII 118
>09736
          Length = 1319

 Score = 40.4 bits (93), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 19/32 (59%), Positives = 22/32 (68%)
 Frame = -2

Query: 220  VKVMTDESGKSKGFGFVSFERHEDAQKAVDEM 251
             KV+ D SGKSKGFGFV F    D Q+A+ EM
Sbjct: 1300 AKVVLDASGKSKGFGFVRFSEENDQQRALVEM 1205

 Score = 38.1 bits (87), Expect = 0.010,   Method: Compositional matrix adjust.
 Identities = 22/61 (36%), Positives = 34/61 (55%), Gaps = 2/61 (3%)
 Frame = -2

Query: 319  TITSAKVMMEG-GRSKGFGFVCFSSPEEATKAVTEMNGRI-VATKPLYVALAQRKEERQA 376
            ++  AKV+++  G+SKGFGFV FS   +  +A+ EM     +  +P+ V LA  K     
Sbjct: 1312 SVRGAKVVLDASGKSKGFGFVRFSEENDQQRALVEMQHMTGIGRRPIKVGLAAPKRGHGF 1133

Query: 377  H 377
            H
Sbjct: 1132 H 1130

 Score = 31.6 bits (70), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 19/49 (38%), Positives = 28/49 (57%), Gaps = 2/49 (4%)
 Frame = -2

Query: 125  ILSCKVVCDENG-SKGYGFVHFETQEAAERAIEKMNGML-LNDRKVFVG 171
            +   KVV D +G SKG+GFV F  +   +RA+ +M  M  +  R + VG
Sbjct: 1309 VRGAKVVLDASGKSKGFGFVRFSEENDQQRALVEMQHMTGIGRRPIKVG 1163
>03406
          Length = 1292

 Score = 40.0 bits (92), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 40/168 (23%), Positives = 74/168 (44%), Gaps = 3/168 (1%)
 Frame = +3

Query: 193 VYIKNFGEDMDDERLKELFGKFGPALSVKVMTD-ESGKSKGFGFVSFERHEDAQKAVDEM 251
           +++     +   + L+E F KFG   S  + TD +SGKS+GFGFV F+        V   
Sbjct: 246 IFVGGLSWETXSKHLREYFEKFGEVTSCTLKTDLDSGKSRGFGFVVFKEAATVDAVVKNK 425

Query: 252 NGKELNGKQIYVGRAQKKVERQTELKRKFEQMKQDRITRYQGVNLYVKNLDDGIDDERLR 311
             K L G++I    A  +           + M++          ++V  LD G+  E + 
Sbjct: 426 EHK-LQGRKIDPKPANPR-----------KGMRK----------IFVGKLDPGVPQEDVE 539

Query: 312 KEFSPFGTITSAKVMMEGGRS--KGFGFVCFSSPEEATKAVTEMNGRI 357
             F+ FG + + ++  +  +   + F FV F + +   K + + + +I
Sbjct: 540 SYFAKFGKVVNVELPYDKVKDQRRAFCFVEFDNDKTVKKVLEQTSHKI 683

 Score = 37.4 bits (85), Expect = 0.021,   Method: Compositional matrix adjust.
 Identities = 23/73 (31%), Positives = 35/73 (47%), Gaps = 6/73 (8%)
 Frame = +3

Query: 296 LYVKNLDDGIDDERLRKEFSPFGTITSA--KVMMEGGRSKGFGFVCFSSPEEATKAVT-- 351
           ++V  L      + LR+ F  FG +TS   K  ++ G+S+GFGFV F         V   
Sbjct: 246 IFVGGLSWETXSKHLREYFEKFGEVTSCTLKTDLDSGKSRGFGFVVFKEAATVDAVVKNK 425

Query: 352 --EMNGRIVATKP 362
             ++ GR +  KP
Sbjct: 426 EHKLQGRKIDPKP 464
>02809
          Length = 1475

 Score = 40.0 bits (92), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 23/72 (31%), Positives = 38/72 (52%), Gaps = 3/72 (4%)
 Frame = -1

Query: 185  ARAKEFT---NVYIKNFGEDMDDERLKELFGKFGPALSVKVMTDESGKSKGFGFVSFERH 241
            +R ++F+    VY+   G     + L++ F K+GP  +V V      +  GF FV FE +
Sbjct: 1361 SRHRDFSLDCKVYVGELGHGCAKQELEDKFAKYGPLKNVWVAR----RPAGFAFVEFEDN 1194

Query: 242  EDAQKAVDEMNG 253
             DA+ AV  ++G
Sbjct: 1193 RDAEDAVQALDG 1158

 Score = 39.7 bits (91), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 19/61 (31%), Positives = 34/61 (55%)
 Frame = -1

Query: 13   LYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQPADAERALDTM 72
            +YVG+L     +  L +KF+  GP+ ++      + RR  G+A+V F+   DAE A+  +
Sbjct: 1328 VYVGELGHGCAKQELEDKFAKYGPLKNV-----WVARRPAGFAFVEFEDNRDAEDAVQAL 1164

Query: 73   N 73
            +
Sbjct: 1163 D 1161
>15503
          Length = 570

 Score = 39.7 bits (91), Expect = 0.004,   Method: Composition-based stats.
 Identities = 27/97 (27%), Positives = 52/97 (53%), Gaps = 5/97 (5%)
 Frame = +1

Query: 193 VYIKNFGEDMDDERLKELFGKFGPALSVKVMTDESGKSKGFGFVSFERHEDAQKAVDEMN 252
           +Y+KN    +  E + ++FGK+G    ++V    + ++KG  FV +E   DA+ A D ++
Sbjct: 154 LYVKNLPYKITAEEMYDIFGKYGAIRQIRV--GNTPETKGTAFVVYEDIFDAKNACDHLS 327

Query: 253 GKELNGKQIYV-----GRAQKKVERQTELKRKFEQMK 284
           G  +  + + V      RA KK++   + K + ++MK
Sbjct: 328 GFNVCNRYLVVLYYQSTRAFKKLDTDKK-KEELDKMK 435

 Score = 33.9 bits (76), Expect = 0.20,   Method: Composition-based stats.
 Identities = 21/77 (27%), Positives = 41/77 (53%)
 Frame = +1

Query: 101 IFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENGSKGYGFVHFETQEAAERAIEKMNG 160
           +++KNL   I  + +YD F  +G I   + V +   +KG  FV +E    A+ A + ++G
Sbjct: 154 LYVKNLPYKITAEEMYDIFGKYGAIRQIR-VGNTPETKGTAFVVYEDIFDAKNACDHLSG 330

Query: 161 MLLNDRKVFVGRFKSRK 177
             + +R + V  ++S +
Sbjct: 331 FNVCNRYLVVLYYQSTR 381

 Score = 30.0 bits (66), Expect = 2.7,   Method: Composition-based stats.
 Identities = 22/83 (26%), Positives = 41/83 (49%)
 Frame = +1

Query: 13  LYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQPADAERALDTM 72
           LYV +L   +T   +Y+ F   G I  IRV     T  + G A+V ++   DA+ A D +
Sbjct: 154 LYVKNLPYKITAEEMYDIFGKYGAIRQIRVGN---TPETKGTAFVVYEDIFDAKNACDHL 324

Query: 73  NFDVIKGKPVRIMWSQRDPSLRK 95
           +   +  + + +++ Q   + +K
Sbjct: 325 SGFNVCNRYLVVLYYQSTRAFKK 393

 Score = 29.3 bits (64), Expect = 5.1,   Method: Composition-based stats.
 Identities = 23/74 (31%), Positives = 32/74 (43%)
 Frame = +1

Query: 296 LYVKNLDDGIDDERLRKEFSPFGTITSAKVMMEGGRSKGFGFVCFSSPEEATKAVTEMNG 355
           LYVKNL   I  E +   F  +G I   +V      +KG  FV +    +A  A   ++G
Sbjct: 154 LYVKNLPYKITAEEMYDIFGKYGAIRQIRV-GNTPETKGTAFVVYEDIFDAKNACDHLSG 330

Query: 356 RIVATKPLYVALAQ 369
             V  + L V   Q
Sbjct: 331 FNVCNRYLVVLYYQ 372
>26197
          Length = 1365

 Score = 39.7 bits (91), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 19/47 (40%), Positives = 28/47 (59%), Gaps = 1/47 (2%)
 Frame = -2

Query: 193  VYIKNFGEDMDDERLKELFGKFGPALSVKVMTD-ESGKSKGFGFVSF 238
            +++     +   + L+E F KFG   S  + TD +SGKS+GFGFV F
Sbjct: 1292 IFVGGLSWETSSKHLREYFEKFGEVTSCTLKTDLDSGKSRGFGFVVF 1152

 Score = 37.0 bits (84), Expect = 0.023,   Method: Compositional matrix adjust.
 Identities = 23/73 (31%), Positives = 35/73 (47%), Gaps = 6/73 (8%)
 Frame = -2

Query: 296  LYVKNLDDGIDDERLRKEFSPFGTITSA--KVMMEGGRSKGFGFVCFSSPEEATKAVT-- 351
            ++V  L      + LR+ F  FG +TS   K  ++ G+S+GFGFV F         V   
Sbjct: 1292 IFVGGLSWETSSKHLREYFEKFGEVTSCTLKTDLDSGKSRGFGFVVFKEAVTVDAVVKNK 1113

Query: 352  --EMNGRIVATKP 362
              ++ GR +  KP
Sbjct: 1112 EHKLQGRKIDPKP 1074
>04988
          Length = 705

 Score = 39.7 bits (91), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 17/36 (47%), Positives = 25/36 (69%)
 Frame = -3

Query: 232 GFGFVSFERHEDAQKAVDEMNGKELNGKQIYVGRAQ 267
           G+GFV FE   DA  AV E+NGK+L G+++ +  A+
Sbjct: 550 GYGFVEFEDFRDADDAVYELNGKDLCGERVIIEHAR 443

 Score = 29.6 bits (65), Expect = 4.1,   Method: Compositional matrix adjust.
 Identities = 18/77 (23%), Positives = 38/77 (49%)
 Frame = -3

Query: 293 GVNLYVKNLDDGIDDERLRKEFSPFGTITSAKVMMEGGRSKGFGFVCFSSPEEATKAVTE 352
           G  +Y+  L     ++ + + F  +G +    +M++     G+GFV F    +A  AV E
Sbjct: 655 GTRVYIGRLPYQAREKDIERFFRGYGRVND--IMLK----NGYGFVEFEDFRDADDAVYE 494

Query: 353 MNGRIVATKPLYVALAQ 369
           +NG+ +  + + +  A+
Sbjct: 493 LNGKDLCGERVIIEHAR 443

 Score = 29.6 bits (65), Expect = 4.2,   Method: Compositional matrix adjust.
 Identities = 13/32 (40%), Positives = 19/32 (59%)
 Frame = -3

Query: 139 GYGFVHFETQEAAERAIEKMNGMLLNDRKVFV 170
           GYGFV FE    A+ A+ ++NG  L   +V +
Sbjct: 550 GYGFVEFEDFRDADDAVYELNGKDLCGERVII 455
>23720
          Length = 739

 Score = 39.7 bits (91), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 17/36 (47%), Positives = 25/36 (69%)
 Frame = -1

Query: 232 GFGFVSFERHEDAQKAVDEMNGKELNGKQIYVGRAQ 267
           G+GFV FE   DA  AV E+NGK+L G+++ +  A+
Sbjct: 583 GYGFVEFEDFRDADDAVYELNGKDLCGERVIIEHAR 476

 Score = 29.6 bits (65), Expect = 4.2,   Method: Compositional matrix adjust.
 Identities = 13/32 (40%), Positives = 19/32 (59%)
 Frame = -1

Query: 139 GYGFVHFETQEAAERAIEKMNGMLLNDRKVFV 170
           GYGFV FE    A+ A+ ++NG  L   +V +
Sbjct: 583 GYGFVEFEDFRDADDAVYELNGKDLCGERVII 488

 Score = 29.3 bits (64), Expect = 4.8,   Method: Compositional matrix adjust.
 Identities = 18/77 (23%), Positives = 38/77 (49%)
 Frame = -1

Query: 293 GVNLYVKNLDDGIDDERLRKEFSPFGTITSAKVMMEGGRSKGFGFVCFSSPEEATKAVTE 352
           G  +Y+  L     ++ + + F  +G +    +M++     G+GFV F    +A  AV E
Sbjct: 688 GTRVYIGRLPYQAREKDIERFFRGYGRVND--IMLK----NGYGFVEFEDFRDADDAVYE 527

Query: 353 MNGRIVATKPLYVALAQ 369
           +NG+ +  + + +  A+
Sbjct: 526 LNGKDLCGERVIIEHAR 476
>08670
          Length = 1307

 Score = 38.1 bits (87), Expect = 0.011,   Method: Compositional matrix adjust.
 Identities = 28/104 (26%), Positives = 52/104 (50%)
 Frame = +2

Query: 1    MNPSAPSYPMASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQ 60
            M+P  P   + +L+VG++ P VTE  L + F+  GP+ S+R+  +         A++N++
Sbjct: 926  MDPKNPEG-LTALWVGNVLPQVTEKRLTQMFAKHGPVASVRMLPEKYC------AFINYK 1084

Query: 61   QPADAERALDTMNFDVIKGKPVRIMWSQRDPSLRKSGVGNIFIK 104
                A RA+  +     +G+ + I    R P    +  GNI ++
Sbjct: 1085 LKESAGRAMQYLQNQECEGQHLLI----RFPDNPINPTGNITLR 1204
>03097
          Length = 1401

 Score = 37.4 bits (85), Expect = 0.017,   Method: Compositional matrix adjust.
 Identities = 20/63 (31%), Positives = 32/63 (50%)
 Frame = +1

Query: 200 EDMDDERLKELFGKFGPALSVKVMTDESGKSKGFGFVSFERHEDAQKAVDEMNGKELNGK 259
           +D  +E   EL  K+G    + +  +      G  +V F + EDA KAV ++N +  NG+
Sbjct: 145 DDFFEEIFIELAEKYGEIEEMNICDNLGDHLVGNVYVKFRKEEDADKAVADLNNRWFNGR 324

Query: 260 QIY 262
            IY
Sbjct: 325 PIY 333

 Score = 30.0 bits (66), Expect = 3.0,   Method: Compositional matrix adjust.
 Identities = 16/48 (33%), Positives = 24/48 (50%)
 Frame = +1

Query: 329 GGRSKGFGFVCFSSPEEATKAVTEMNGRIVATKPLYVALAQRKEERQA 376
           G    G  +V F   E+A KAV ++N R    +P+Y  L    + R+A
Sbjct: 226 GDHLVGNVYVKFRKEEDADKAVADLNNRWFNGRPIYAELTPVTDFREA 369
>10194
          Length = 1278

 Score = 37.4 bits (85), Expect = 0.019,   Method: Compositional matrix adjust.
 Identities = 21/67 (31%), Positives = 32/67 (47%)
 Frame = -3

Query: 12  SLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQPADAERALDT 71
           S++VG+L  D+ E  +   F   G + +IRV RD  T    G  Y+ F+       AL  
Sbjct: 403 SVFVGNLPFDIEEESVRSHFEDCGDVENIRVVRDRKTNLGKGICYILFKSADSVSLALKL 224

Query: 72  MNFDVIK 78
            N ++ K
Sbjct: 223 NNSELEK 203
>28372
          Length = 398

 Score = 37.0 bits (84), Expect = 0.024,   Method: Composition-based stats.
 Identities = 15/33 (45%), Positives = 24/33 (72%)
 Frame = -2

Query: 231 KGFGFVSFERHEDAQKAVDEMNGKELNGKQIYV 263
           +GFGFV+F    +A++A D+MNG  + G++I V
Sbjct: 259 QGFGFVTFAHSAEAERARDKMNGTVVEGRKIEV 161

 Score = 35.4 bits (80), Expect = 0.062,   Method: Composition-based stats.
 Identities = 16/33 (48%), Positives = 22/33 (66%)
 Frame = -2

Query: 138 KGYGFVHFETQEAAERAIEKMNGMLLNDRKVFV 170
           +G+GFV F     AERA +KMNG ++  RK+ V
Sbjct: 259 QGFGFVTFAHSAEAERARDKMNGTVVEGRKIEV 161

 Score = 32.0 bits (71), Expect = 0.71,   Method: Composition-based stats.
 Identities = 14/33 (42%), Positives = 21/33 (63%)
 Frame = -2

Query: 333 KGFGFVCFSSPEEATKAVTEMNGRIVATKPLYV 365
           +GFGFV F+   EA +A  +MNG +V  + + V
Sbjct: 259 QGFGFVTFAHSAEAERARDKMNGTVVEGRKIEV 161
>12096
          Length = 1585

 Score = 36.6 bits (83), Expect = 0.028,   Method: Compositional matrix adjust.
 Identities = 17/53 (32%), Positives = 31/53 (58%)
 Frame = -3

Query: 202  MDDERLKELFGKFGPALSVKVMTDESGKSKGFGFVSFERHEDAQKAVDEMNGK 254
            ++++ ++EL     P   V+ M   +G S+GFGFV F+   +AQ+ +D   G+
Sbjct: 1187 VENDIIQELIRIGMPPKDVRFMRRVTGASRGFGFVEFQSQSEAQRWMDHNQGQ 1029

 Score = 29.6 bits (65), Expect = 3.4,   Method: Compositional matrix adjust.
 Identities = 13/29 (44%), Positives = 18/29 (62%)
 Frame = -3

Query: 330  GRSKGFGFVCFSSPEEATKAVTEMNGRIV 358
            G S+GFGFV F S  EA + +    G++V
Sbjct: 1109 GASRGFGFVEFQSQSEAQRWMDHNQGQVV 1023
>05273
          Length = 1009

 Score = 36.6 bits (83), Expect = 0.029,   Method: Compositional matrix adjust.
 Identities = 17/35 (48%), Positives = 24/35 (68%), Gaps = 1/35 (2%)
 Frame = -1

Query: 204 DERLKELFGKFGPALSVKVMTD-ESGKSKGFGFVS 237
           D  L+E F KFG      V+TD ++GKS+G+GFV+
Sbjct: 160 DHSLREYFDKFGDIDEAVVITDRQTGKSRGYGFVT 56
>31618
          Length = 716

 Score = 36.2 bits (82), Expect = 0.037,   Method: Compositional matrix adjust.
 Identities = 43/155 (27%), Positives = 68/155 (43%), Gaps = 16/155 (10%)
 Frame = +1

Query: 13  LYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNF-------QQPADA 65
           L+VG L  + TE  L + F   G I SI V  D  T RS G+A++ F       Q  A  
Sbjct: 298 LFVGGLSWETTEKELRDHFGKYGEIESINVKTDPQTGRSRGFAFIVFTNTEAIDQVSAAE 477

Query: 66  ERALDTMNFDVIKGKP-------VRIMWSQRDPSLRKSGVGNIFIKNLDKSIDNKALYDT 118
           E  +++   D  K KP       + +   QR  ++RKS   ++   NLD           
Sbjct: 478 EHIINSKKVDP-KKKPRLAMARFLSVA*PQR-LAMRKSKPTSV---NLD----------- 609

Query: 119 FSAFGNILSCKVVCDENGS--KGYGFVHFETQEAA 151
                NI+  ++  D+  S  KG+ F+ F++++  
Sbjct: 610 -----NIVEVEMPFDKQKSHRKGFXFITFDSEQVV 699

 Score = 36.2 bits (82), Expect = 0.041,   Method: Compositional matrix adjust.
 Identities = 22/70 (31%), Positives = 35/70 (50%), Gaps = 2/70 (2%)
 Frame = +1

Query: 296 LYVKNLDDGIDDERLRKEFSPFGTITSAKVMME--GGRSKGFGFVCFSSPEEATKAVTEM 353
           L+V  L     ++ LR  F  +G I S  V  +   GRS+GF F+ F++  EA   V+  
Sbjct: 298 LFVGGLSWETTEKELRDHFGKYGEIESINVKTDPQTGRSRGFAFIVFTNT-EAIDQVSAA 474

Query: 354 NGRIVATKPL 363
              I+ +K +
Sbjct: 475 EEHIINSKKV 504
>39789
          Length = 361

 Score = 35.0 bits (79), Expect = 0.10,   Method: Compositional matrix adjust.
 Identities = 22/69 (31%), Positives = 35/69 (50%)
 Frame = +1

Query: 193 VYIKNFGEDMDDERLKELFGKFGPALSVKVMTDESGKSKGFGFVSFERHEDAQKAVDEMN 252
           +++ N   D D   LK+ F     A   K    ++ K +GFGFV F   +DA  A D   
Sbjct: 94  LFVGNLSYDTDQYSLKDAFPGATAARIAKFQ--DTQKPRGFGFVEFSTPDDAASAFDSGE 267

Query: 253 GKELNGKQI 261
            +E++G+Q+
Sbjct: 268 -REVDGRQV 291

 Score = 34.3 bits (77), Expect = 0.15,   Method: Compositional matrix adjust.
 Identities = 23/67 (34%), Positives = 33/67 (49%), Gaps = 4/67 (5%)
 Frame = +1

Query: 296 LYVKNLDDGIDDERLRKEFSPFGTITSAKVMMEGGRSKGFGFVCFSSPEEATKAVT---- 351
           L+V NL    D   L+  F P  T        +  + +GFGFV FS+P++A  A      
Sbjct: 94  LFVGNLSYDTDQYSLKDAF-PGATAARIAKFQDTQKPRGFGFVEFSTPDDAASAFDSGER 270

Query: 352 EMNGRIV 358
           E++GR V
Sbjct: 271 EVDGRQV 291
>00781
          Length = 3170

 Score = 35.0 bits (79), Expect = 0.10,   Method: Compositional matrix adjust.
 Identities = 23/61 (37%), Positives = 30/61 (49%), Gaps = 2/61 (3%)
 Frame = -1

Query: 296  LYVKNLDDGIDDERLRKEFSPFGTIT--SAKVMMEGGRSKGFGFVCFSSPEEATKAVTEM 353
            +YV+        E + + FS  GT+T  S          KG+ FV F SPEEA KAV  +
Sbjct: 2714 VYVEGFHKFTSREWISRMFSKCGTVTYVSLPCFKTTREIKGYAFVEFQSPEEAVKAVQML 2535

Query: 354  N 354
            N
Sbjct: 2534 N 2532

 Score = 29.3 bits (64), Expect = 4.6,   Method: Compositional matrix adjust.
 Identities = 19/61 (31%), Positives = 32/61 (52%), Gaps = 1/61 (1%)
 Frame = -1

Query: 193  VYIKNFGEDMDDERLKELFGKFGPALSVKVMTDESGKS-KGFGFVSFERHEDAQKAVDEM 251
            VY++ F +    E +  +F K G    V +   ++ +  KG+ FV F+  E+A KAV  +
Sbjct: 2714 VYVEGFHKFTSREWISRMFSKCGTVTYVSLPCFKTTREIKGYAFVEFQSPEEAVKAVQML 2535

Query: 252  N 252
            N
Sbjct: 2534 N 2532
>25950
          Length = 417

 Score = 34.7 bits (78), Expect = 0.13,   Method: Compositional matrix adjust.
 Identities = 22/63 (34%), Positives = 30/63 (47%), Gaps = 2/63 (3%)
 Frame = -2

Query: 284 KQDRITRYQGVNLYVKNLDDGIDDERLRKEFSPFGTITSAKVMME--GGRSKGFGFVCFS 341
           KQ+  TR    ++YV N+D G   E L   F   GTI    ++     G  KGF ++ F 
Sbjct: 299 KQEIDTR----SVYVGNVDYGASAEELEAHFHGCGTINRVTILCNKADGHPKGFAYIEFG 132

Query: 342 SPE 344
           S E
Sbjct: 131 SKE 123

 Score = 33.5 bits (75), Expect = 0.25,   Method: Compositional matrix adjust.
 Identities = 19/74 (25%), Positives = 34/74 (45%)
 Frame = -2

Query: 12  SLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQPADAERALDT 71
           S+YVG++    +   L   F   G I  + +  +       G+AY+ F      E AL  
Sbjct: 278 SVYVGNVDYGASAEELEAHFHGCGTINRVTILCNKADGHPKGFAYIEFGSKEYVETAL-A 102

Query: 72  MNFDVIKGKPVRIM 85
           MN  + +G+ +++M
Sbjct: 101 MNETLFRGRQIKVM 60

 Score = 32.7 bits (73), Expect = 0.46,   Method: Compositional matrix adjust.
 Identities = 18/73 (24%), Positives = 36/73 (49%), Gaps = 2/73 (2%)
 Frame = -2

Query: 100 NIFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENGS--KGYGFVHFETQEAAERAIEK 157
           ++++ N+D     + L   F   G I    ++C++     KG+ ++ F ++E  E A+  
Sbjct: 278 SVYVGNVDYGASAEELEAHFHGCGTINRVTILCNKADGHPKGFAYIEFGSKEYVETAL-A 102

Query: 158 MNGMLLNDRKVFV 170
           MN  L   R++ V
Sbjct: 101 MNETLFRGRQIKV 63
>32733
          Length = 709

 Score = 34.7 bits (78), Expect = 0.14,   Method: Compositional matrix adjust.
 Identities = 16/42 (38%), Positives = 27/42 (64%), Gaps = 1/42 (2%)
 Frame = +1

Query: 119 FSAFGNILSCKVVCDENG-SKGYGFVHFETQEAAERAIEKMN 159
           F +FG+I  C V+ D NG S+G  F+ F +++ A  +I+ M+
Sbjct: 526 FESFGSIDDCTVLRDSNGTSRGCAFITFASRQCAMNSIKGMH 651
>25632
          Length = 864

 Score = 33.5 bits (75), Expect = 0.25,   Method: Compositional matrix adjust.
 Identities = 16/53 (30%), Positives = 25/53 (47%)
 Frame = -2

Query: 118 TFSAFGNILSCKVVCDENGSKGYGFVHFETQEAAERAIEKMNGMLLNDRKVFV 170
               +G +  C V+      K YGFVH  T+  A  AI  +NG  +  +++ V
Sbjct: 710 CLEKYGTVEECDVL------KNYGFVHMPTKSEASAAITNLNGYNIKGQRMRV 570

 Score = 31.6 bits (70), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 16/55 (29%), Positives = 28/55 (50%)
 Frame = -2

Query: 317 FGTITSAKVMMEGGRSKGFGFVCFSSPEEATKAVTEMNGRIVATKPLYVALAQRK 371
           +GT+    V+      K +GFV   +  EA+ A+T +NG  +  + + V L+  K
Sbjct: 698 YGTVEECDVL------KNYGFVHMPTKSEASAAITNLNGYNIKGQRMRVELSTNK 552
>11579
          Length = 1307

 Score = 32.7 bits (73), Expect = 0.52,   Method: Compositional matrix adjust.
 Identities = 14/38 (36%), Positives = 24/38 (63%)
 Frame = +3

Query: 51 SLGYAYVNFQQPADAERALDTMNFDVIKGKPVRIMWSQ 88
          S G+A+V F    DAE A+D+M+  ++ G+ VR   ++
Sbjct: 3  SRGFAFVRFYDRRDAEDAMDSMDGALLDGREVRCQMAR 116
>23655
          Length = 929

 Score = 31.6 bits (70), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 17/39 (43%), Positives = 25/39 (64%)
 Frame = -3

Query: 231 KGFGFVSFERHEDAQKAVDEMNGKELNGKQIYVGRAQKK 269
           +GF FV+F  H+   KAV +    +LNG+Q+ V +AQ K
Sbjct: 783 QGFCFVTFGDHDSVDKAVLKKR-HDLNGRQVEVKKAQSK 670
>30934
          Length = 809

 Score = 30.8 bits (68), Expect = 1.8,   Method: Compositional matrix adjust.
 Identities = 51/203 (25%), Positives = 84/203 (41%), Gaps = 16/203 (7%)
 Frame = +1

Query: 34  AGPILSIRVCRDMITRRSLGYAYVNFQQPADAERALDTMNFDVIKGKPVRIM----WSQR 89
            GP+  + +  D IT++  G+A+V F  P  A +A   ++    +G+ + I+     +Q+
Sbjct: 25  GGPVTDLDLPVDPITKKIKGFAHVTFMFPEHAVKARMELDRQGFRGRMLHILPGKDRTQK 204

Query: 90  DPSLRKSGVGNI---FIKNLDKSIDN-KALYDTFSAFGNILSCKVVCDEN--------GS 137
             S  KS    +     K L KS  N   L+ +  A    ++ K   D++        GS
Sbjct: 205 YVSHEKSSYKKLKDEKTKALVKSSHNWNTLFLSGDAVATAMATKYXADKSDILDDSGKGS 384

Query: 138 KGYGFVHFETQEAAERAIEKMNGMLLNDRKVFVGRFKSRKEREAELGARAKEFTNVYIKN 197
            G      ETQ   E          L D  V +  F      +A+ GAR+K  T +  K+
Sbjct: 385 LGVRMALGETQLVQE------TRQFLIDNGVALDSFS-----QAD-GARSK--TVIIAKD 522

Query: 198 FGEDMDDERLKELFGKFGPALSV 220
                + + L E+F K+G    V
Sbjct: 523 LPAATESDXLTEVFSKYGTVARV 591
>11126
          Length = 1061

 Score = 30.4 bits (67), Expect = 2.2,   Method: Compositional matrix adjust.
 Identities = 17/75 (22%), Positives = 33/75 (44%)
 Frame = -3

Query: 10  MASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQPADAERAL 69
           + S+YVG++    T   L + F   G +  + +  D  +    G+AYV F        A 
Sbjct: 633 LRSVYVGNVDYGATAEELEQHFHGCGSVNRVTILCDKYSGHPKGFAYVEFADKDSVVTAK 454

Query: 70  DTMNFDVIKGKPVRI 84
            T    + +G+ +++
Sbjct: 453 CTGMDSLFRGRQIKV 409
>31265
          Length = 540

 Score = 29.6 bits (65), Expect = 3.7,   Method: Compositional matrix adjust.
 Identities = 33/127 (25%), Positives = 59/127 (46%), Gaps = 9/127 (7%)
 Frame = +2

Query: 53  GYAYVNF---QQPADAERALDTMNFDVIKGKPVRIMWSQRDPSLRK---SGVGNIFIKNL 106
           G+A+V +   +  A A R L       + G  + + W++ +  + +   S V  + ++NL
Sbjct: 5   GFAFVEYTSHRAAAMARRKLIPGRIQ-LWGHQIAVDWAEPEQDVDEDTMSQVKILXVRNL 181

Query: 107 DKSIDNKALYDTFS-AFGN--ILSCKVVCDENGSKGYGFVHFETQEAAERAIEKMNGMLL 163
             +   + L D FS A G   I   K + D      Y FVHF ++E A +A++  +G  +
Sbjct: 182 MLTTTEETLKDVFSRAAGGREIERVKKIRD------YAFVHFRSREDAIKAMDVTDGSTI 343

Query: 164 NDRKVFV 170
              +V V
Sbjct: 344 EGSQVEV 364
>26275
          Length = 896

 Score = 28.9 bits (63), Expect = 7.1,   Method: Compositional matrix adjust.
 Identities = 13/32 (40%), Positives = 18/32 (56%)
 Frame = +1

Query: 144 HFETQEAAERAIEKMNGMLLNDRKVFVGRFKS 175
           H E Q    RA E+M+  LL  R VF+ + K+
Sbjct: 628 HLEEQAVKRRAKEEMDKKLLEQRAVFIEKAKT 723
>19556
          Length = 917

 Score = 28.5 bits (62), Expect = 7.9,   Method: Compositional matrix adjust.
 Identities = 24/99 (24%), Positives = 44/99 (44%), Gaps = 3/99 (3%)
 Frame = -1

Query: 14  YVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQPADA-ERALDTM 72
           ++G L   VTE  L EKFS  G + ++ +        S  +AYVN     +  ++     
Sbjct: 821 FIGGLVKGVTEEELMEKFSRFGQVSNVDIKTRTNGIDSRTFAYVNLTAEENGFKKCFTAY 642

Query: 73  NFDVIKGKPVRIMWSQRD--PSLRKSGVGNIFIKNLDKS 109
           N    KG  +++ +++      L+K       +K+ +KS
Sbjct: 641 NNTKWKGGQLKLQYAKESSLSKLKKEQTEARLVKDKEKS 525
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|52345394|ref|NP_001004365.1| ARP3 actin-related
protein 3 homolog B [Mus musculus]
         (418 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

00608                                                                 596   e-171
19721                                                                 202   4e-97
13361                                                                 325   2e-89
04742                                                                 253   7e-68
39562                                                                 212   2e-55
12322                                                                 126   1e-29
02757                                                                  82   7e-29
36954                                                                  97   8e-21
01436                                                                  82   5e-16
17032                                                                  82   6e-16
32273                                                                  79   3e-15
11487                                                                  44   2e-11
18926                                                                  62   4e-10
28457                                                                  32   0.71 
>00608
          Length = 1930

 Score =  596 bits (1536), Expect = e-171,   Method: Compositional matrix adjust.
 Identities = 286/337 (84%), Positives = 315/337 (93%)
 Frame = +3

Query: 82  IVEDWDLMERFMEQVVFKYLRAEPEDHYFLMTEPPLNTPENREYLAEIMFESFNVPGLYI 141
           I++DWDLMERF EQV+FKYLRAEPEDHYFL+TEPPLNTPENREY AEIMFESFNVPGLYI
Sbjct: 3   IIDDWDLMERFYEQVIFKYLRAEPEDHYFLLTEPPLNTPENREYTAEIMFESFNVPGLYI 182

Query: 142 AVQAVLALAASWTSRQVGERTLTGIVIDSGDGVTHVIPVAEGYVIGSCIKHIPIAGRDIT 201
           AVQAVLALAASWTSR VGERTLTG VIDSGDGVTHVIPVAEGYVIGSCIKHIPIAGRDIT
Sbjct: 183 AVQAVLALAASWTSRNVGERTLTGTVIDSGDGVTHVIPVAEGYVIGSCIKHIPIAGRDIT 362

Query: 202 YFIQQLLREREVGIPPEQSLETAKAIKEKYCYICPDIVREFAKYDVDPRKWIKQYTGINA 261
           YFIQQLLREREVGIPPEQSLETAKAIKE++ Y+CPDI +EF+KYD DP KW+K+Y G N 
Sbjct: 363 YFIQQLLREREVGIPPEQSLETAKAIKERFSYVCPDIAKEFSKYDTDPSKWMKKYEGRNT 542

Query: 262 INQKKFIIDVGYERFLGPEIFFHPEFANPDFMESISDVVDEVIQSCPIDVRRPLYKNVVL 321
           I+++ F +DVGYERFLGPEIFFHPEF+NPDF   ISDVVD+VIQ+CPIDVRR LYKN+VL
Sbjct: 543 ISKQLFSVDVGYERFLGPEIFFHPEFSNPDFTMPISDVVDDVIQNCPIDVRRGLYKNIVL 722

Query: 322 SGGSTMFRDFGRRLQRDLKRVVDARLKLSQELSGGRIKPKPVEVQVVTHHMQRYAVWFGG 381
           SGGSTMFRDFGR++QRD+KRVVD RLK S+ELS GRIKPKP+EVQV+THHMQRYAVWFGG
Sbjct: 723 SGGSTMFRDFGRKIQRDVKRVVDGRLKASEELSQGRIKPKPIEVQVITHHMQRYAVWFGG 902

Query: 382 SMLASTPEFFQVCHTKKDYEEYGPSICRHNPVFGVMS 418
           SMLASTPEF+QVCHTK DY+E+GPSICRHNPVFG M+
Sbjct: 903 SMLASTPEFYQVCHTKADYDEHGPSICRHNPVFGTMA 1013
>19721
          Length = 757

 Score =  202 bits (514), Expect(2) = 4e-97,   Method: Compositional matrix adjust.
 Identities = 104/121 (85%), Positives = 112/121 (92%)
 Frame = +2

Query: 82  IVEDWDLMERFMEQVVFKYLRAEPEDHYFLMTEPPLNTPENREYLAEIMFESFNVPGLYI 141
           +VEDWDL ERFMEQ +FKYLRAEPEDHYFL+TEPPLNTPENRE+ AEIMFE+FN+PGLYI
Sbjct: 2   VVEDWDLHERFMEQAIFKYLRAEPEDHYFLLTEPPLNTPENREFTAEIMFETFNIPGLYI 181

Query: 142 AVQAVLALAASWTSRQVGERTLTGIVIDSGDGVTHVIPVAEGYVIGSCIKHIPIAGRDIT 201
           AVQAVLALAASWTSR   ERTLTG VIDSGDGVTHVIPV +GYVIGS IKHIPIAGRDIT
Sbjct: 182 AVQAVLALAASWTSRPPNERTLTGTVIDSGDGVTHVIPVVDGYVIGSAIKHIPIAGRDIT 361

Query: 202 Y 202
           +
Sbjct: 362 F 364

 Score =  170 bits (431), Expect(2) = 4e-97,   Method: Compositional matrix adjust.
 Identities = 79/134 (58%), Positives = 94/134 (70%)
 Frame = +3

Query: 200 ITYFIQQLLREREVGIPPEQSLETAKAIKEKYCYICPDIVREFAKYDVDPRKWIKQYTGI 259
           I++F   +       IPP+ S+E AK IKE+Y Y+CPDI +EFAKYD DP KWIK +   
Sbjct: 354 ISHFHPAIATGTGTVIPPDMSMEAAKQIKERYSYVCPDIAKEFAKYDSDPEKWIKAHKMS 533

Query: 260 NAINQKKFIIDVGYERFLGPEIFFHPEFANPDFMESISDVVDEVIQSCPIDVRRPLYKNV 319
            +     F  DVGYE+FLGPE+FF PEF N DF  SISDVVD VIQSCPID RRPLY N+
Sbjct: 534 GSSKYPDFSFDVGYEKFLGPEVFFRPEFVNGDFQASISDVVDTVIQSCPIDSRRPLYNNI 713

Query: 320 VLSGGSTMFRDFGR 333
           VLSGGS+MF+   R
Sbjct: 714 VLSGGSSMFKHLDR 755
>13361
          Length = 1217

 Score =  325 bits (832), Expect = 2e-89,   Method: Compositional matrix adjust.
 Identities = 142/187 (75%), Positives = 166/187 (88%)
 Frame = +3

Query: 232 CYICPDIVREFAKYDVDPRKWIKQYTGINAINQKKFIIDVGYERFLGPEIFFHPEFANPD 291
           CYICPDI +EFAKYD +P KWI+ YTG+N + ++ F +DVGYERFLGPEIFFHPEF+NPD
Sbjct: 42  CYICPDIAKEFAKYDSEPSKWIRNYTGMNTVTKQAFNVDVGYERFLGPEIFFHPEFSNPD 221

Query: 292 FMESISDVVDEVIQSCPIDVRRPLYKNVVLSGGSTMFRDFGRRLQRDLKRVVDARLKLSQ 351
           F   +S++VD VIQ+CPIDVRR LY N+VLSGGSTMF+DFGRRLQRD+KR VD RL++S+
Sbjct: 222 FTIPLSEIVDNVIQNCPIDVRRHLYNNIVLSGGSTMFKDFGRRLQRDIKRSVDTRLRISE 401

Query: 352 ELSGGRIKPKPVEVQVVTHHMQRYAVWFGGSMLASTPEFFQVCHTKKDYEEYGPSICRHN 411
            LS GRIKPKP++VQV+THHMQRYAVWFGGSMLASTPEF+QVCHTK  YEEYGPSICRHN
Sbjct: 402 NLSEGRIKPKPIDVQVITHHMQRYAVWFGGSMLASTPEFYQVCHTKAAYEEYGPSICRHN 581

Query: 412 PVFGVMS 418
           PVFG M+
Sbjct: 582 PVFGTMT 602
>04742
          Length = 2111

 Score =  253 bits (647), Expect = 7e-68,   Method: Compositional matrix adjust.
 Identities = 147/415 (35%), Positives = 218/415 (52%), Gaps = 9/415 (2%)
 Frame = +2

Query: 9   VVDCGTGYTKLGYAGNTEPQFIIPSCIAIRESAKVVDQAQRRVLRGVDDLDFFIGDEAID 68
           V+D G+G  K G+AG+  P+ + PS +             + V+ G+   D ++GDEA  
Sbjct: 119 VIDNGSGMCKAGFAGDDAPRAVFPSIVG--------RPRHQGVMVGMGQKDSYVGDEAQS 274

Query: 69  KPTYAT-KWPIRHGIVEDWDLMERFMEQVVFKYLRAEPEDHYFLMTEPPLNTPENREYLA 127
           K    T K+PI HGIV +WD ME+      +  LR  PE+H  L+TE PLN   NRE + 
Sbjct: 275 KRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMT 454

Query: 128 EIMFESFNVPGLYIAVQAVLALAASWTSRQVGERTLTGIVIDSGDGVTHVIPVAEGYVIG 187
           +IMFE+FN P +Y+A+QAVL+L AS  +        TGIV+DSGDGV H +P+ EGY + 
Sbjct: 455 QIMFETFNSPAMYVAIQAVLSLYASGRT--------TGIVLDSGDGVXHTVPIYEGYALP 610

Query: 188 SCIKHIPIAGRDITYFIQQLLREREVGIPPEQSLETAKAIKEKYCYICPDIVREFAKYDV 247
             I  + +AGRD+T ++ ++L ER          E  + IKEK CY+  D  +E      
Sbjct: 611 HAISRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEM----- 775

Query: 248 DPRKWIKQYTGINAINQKKF------IIDVGYERFLGPEIFFHPEFANPDFMESIS--DV 299
                  Q    ++  +K +      +I +G ERF  PE  F P F     MES    + 
Sbjct: 776 -------QTAASSSSLEKSYELPDGQVITIGNERFRCPEAMFQPSFLG---MESAGXHET 925

Query: 300 VDEVIQSCPIDVRRPLYKNVVLSGGSTMFRDFGRRLQRDLKRVVDARLKLSQELSGGRIK 359
               I  C +D+R+ LY N VLSGGSTM+     R+Q+++                  + 
Sbjct: 926 TYNSIMKCDVDIRKDLYANTVLSGGSTMYPGIADRMQKEIT----------------ALA 1057

Query: 360 PKPVEVQVVTHHMQRYAVWFGGSMLASTPEFFQVCHTKKDYEEYGPSICRHNPVF 414
           P  ++++++    ++Y+VW GGS+LAS   F Q+  +K++Y+E GPSI  H   F
Sbjct: 1058PPTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIV-HRKCF 1219
>39562
          Length = 1438

 Score =  212 bits (539), Expect = 2e-55,   Method: Compositional matrix adjust.
 Identities = 123/335 (36%), Positives = 178/335 (53%), Gaps = 2/335 (0%)
 Frame = -2

Query: 82   IVEDWDLMERFMEQVVFKYLRAEPEDHYFLMTEPPLNTPENREYLAEIMFESFNVPGLYI 141
            IV +WD ME+      +  LR  PE+H  L+TE PLN   NRE + +IMFE+FN P +Y+
Sbjct: 1437 IVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNSPAMYV 1258

Query: 142  AVQAVLALAASWTSRQVGERTLTGIVIDSGDGVTHVIPVAEGYVIGSCIKHIPIAGRDIT 201
            A+QAVL+L AS  +        TGIV+DSGDGVTH +P+ EGY +   I  + +AGRD+T
Sbjct: 1257 AIQAVLSLYASGRT--------TGIVLDSGDGVTHTVPIYEGYALPHAIMRLDLAGRDLT 1102

Query: 202  YFIQQLLREREVGIPPEQSLETAKAIKEKYCYICPDIVREFAKYDVDPRKWIKQYTGINA 261
             ++ ++L ER          E  + IKEK  Y+  D  +E            K Y   + 
Sbjct: 1101 DYLMKILTERGYSFTTTAEREIVRDIKEKLDYVALDFEQEMLT-AASSSSLEKSYELPDG 925

Query: 262  INQKKFIIDVGYERFLGPEIFFHPEFANPDFMES--ISDVVDEVIQSCPIDVRRPLYKNV 319
                  +I +G ERF  PE  F P F     MES  I +     I  C +D+R+ LY N 
Sbjct: 924  Q-----VITIGNERFRCPEAMFQPSFLG---MESAGIHETTYNSIMKCDVDIRKDLYANT 769

Query: 320  VLSGGSTMFRDFGRRLQRDLKRVVDARLKLSQELSGGRIKPKPVEVQVVTHHMQRYAVWF 379
            VLSGGSTM+     R+Q+++                  + P  ++++++    ++Y+VW 
Sbjct: 768  VLSGGSTMYPGIADRMQKEIT----------------ALAPPTMKIKIIAPPERKYSVWI 637

Query: 380  GGSMLASTPEFFQVCHTKKDYEEYGPSICRHNPVF 414
            GGS+LAS   F Q+  +K++Y+E GPSI  H   F
Sbjct: 636  GGSILASLSTFQQMWISKQEYDESGPSIV-HRKCF 535
>12322
          Length = 849

 Score =  126 bits (317), Expect = 1e-29,   Method: Compositional matrix adjust.
 Identities = 74/231 (32%), Positives = 121/231 (52%)
 Frame = +1

Query: 174 VTHVIPVAEGYVIGSCIKHIPIAGRDITYFIQQLLREREVGIPPEQSLETAKAIKEKYCY 233
           VTH +PV EG+ +   I  + +AGRD+T +++ LLR+  + +      E  K IKE+ CY
Sbjct: 1   VTHAVPVYEGFAMPHSIMRVDVAGRDVTRYLRLLLRKEGMDLHTTAEFEVVKHIKERTCY 180

Query: 234 ICPDIVREFAKYDVDPRKWIKQYTGINAINQKKFIIDVGYERFLGPEIFFHPEFANPDFM 293
           +  + ++E +   VD  K        N +       +VG  RF  PE+ F P+    +  
Sbjct: 181 LSINPLKEES---VDTEKVSYTLPDGNTV-------EVGPARFRAPELLFRPDLIGEE-C 327

Query: 294 ESISDVVDEVIQSCPIDVRRPLYKNVVLSGGSTMFRDFGRRLQRDLKRVVDARLKLSQEL 353
           E I +V+   IQ   +D+R+ LY N+VLSGGST+F+ FG RL  +LK++           
Sbjct: 328 EGIHEVLSYSIQKSDVDLRKTLYSNIVLSGGSTLFKGFGDRLLSELKKLA---------- 477

Query: 354 SGGRIKPKPVEVQVVTHHMQRYAVWFGGSMLASTPEFFQVCHTKKDYEEYG 404
                 PK +++++     + Y+ W G S+LAS   F ++  +K++Y E G
Sbjct: 478 ------PKDIKIRISAPQERLYSTWIGXSILASLDTFRKMWVSKREYHEEG 612
>02757
          Length = 1094

 Score = 81.6 bits (200), Expect(3) = 7e-29,   Method: Compositional matrix adjust.
 Identities = 52/154 (33%), Positives = 74/154 (48%), Gaps = 2/154 (1%)
 Frame = -2

Query: 188 SCIKHIPIAGRDITYFIQQLLREREVGIPPEQSLETAKAIKEKYCYICPDIVREFAKYDV 247
           + I  + +AGRD+T ++ ++L ER          E    IKEK CY+  D  +E A    
Sbjct: 994 TAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVXDIKEKLCYVALDFEQEMATA-A 818

Query: 248 DPRKWIKQYTGINAINQKKFIIDVGYERFLGPEIFFHPEFANPDFMES--ISDVVDEVIQ 305
                 K Y   +       +I +G ERF  PE  F P F     MES  I +     I 
Sbjct: 817 SSSSLEKSYELPDG-----QVITIGNERFRCPESLFQPSFLG---MESAGIHETTYNSIM 662

Query: 306 SCPIDVRRPLYKNVVLSGGSTMFRDFGRRLQRDL 339
            C +D+R+ LY N VLSGG+TMF     R+Q+++
Sbjct: 661 KCDVDIRKDLYANTVLSGGTTMFPGIADRMQKEI 560

 Score = 43.5 bits (101), Expect(3) = 7e-29,   Method: Compositional matrix adjust.
 Identities = 18/45 (40%), Positives = 32/45 (71%)
 Frame = -3

Query: 363 VEVQVVTHHMQRYAVWFGGSMLASTPEFFQVCHTKKDYEEYGPSI 407
           ++++ +    ++Y+VW GGS+LAS   F Q+  +K++Y+E GPSI
Sbjct: 537 MKIKXIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSI 403

 Score = 40.0 bits (92), Expect(3) = 7e-29,   Method: Compositional matrix adjust.
 Identities = 16/23 (69%), Positives = 20/23 (86%)
 Frame = -1

Query: 164  TGIVIDSGDGVTHVIPVAEGYVI 186
            TGIV+DSGDGVTH +P+ EGY +
Sbjct: 1067 TGIVLDSGDGVTHTVPIYEGYAL 999
>36954
          Length = 892

 Score = 97.4 bits (241), Expect = 8e-21,   Method: Compositional matrix adjust.
 Identities = 61/224 (27%), Positives = 106/224 (47%), Gaps = 2/224 (0%)
 Frame = -1

Query: 9   VVDCGTGYTKLGYAGNTEPQFIIPSCIAIRESAKVVDQAQRRVLRGVDDLDFFIGDEAID 68
           V D G+   + GYAG   P+  IP+ + + E  +              +  + I    + 
Sbjct: 799 VFDIGSYSFRAGYAGEDTPKAEIPTHVGVMEDIETTMDTDGGDAPPQPEKKYLIDTVYMK 620

Query: 69  KPTYATKWP--IRHGIVEDWDLMERFMEQVVFKYLRAEPEDHYFLMTEPPLNTPENREYL 126
            P         ++ G+VEDWD+ E+ ++    + +++E   H  LM+EP  NT   RE L
Sbjct: 619 HPRKGMHLNSFLKDGMVEDWDMFEKVIDYAYNRSIKSESCLHPLLMSEPAWNTKAKREKL 440

Query: 127 AEIMFESFNVPGLYIAVQAVLALAASWTSRQVGERTLTGIVIDSGDGVTHVIPVAEGYVI 186
            EIMFE +N+P  ++   +VL+  A+  S        T +++DSG   T  +PV +GYV+
Sbjct: 439 TEIMFEKYNIPAFFLRKNSVLSAFANGRS--------TALILDSGATHTSAVPVYDGYVL 284

Query: 187 GSCIKHIPIAGRDITYFIQQLLREREVGIPPEQSLETAKAIKEK 230
              I   P+AG  I      L+ E+ + + P   + + + + +K
Sbjct: 283 TQGIVKSPLAGDFIARECGLLMEEQNIEVVPPYLISSKEVVADK 152
>01436
          Length = 2563

 Score = 81.6 bits (200), Expect = 5e-16,   Method: Compositional matrix adjust.
 Identities = 61/213 (28%), Positives = 106/213 (49%), Gaps = 4/213 (1%)
 Frame = +3

Query: 200 ITYFIQQLLREREVGIPPEQSLETAKAIKEKYCYICPDIVREFAKYDVDPRKWIKQYTGI 259
           IT ++ +LL  R          ET + +KEK CY   D+ +E  K  ++    ++ Y   
Sbjct: 3   ITRYLIKLLLLRGYAFNHSADFETVRMLKEKLCYTAYDVEQE-QKLALETTVLVEPY--- 170

Query: 260 NAINQKKFIIDVGYERFLGPEIFFHPEFANPDFMESISDVVDEVIQSCPIDVRRPLYKNV 319
             I     +I VG ERF  PE  F P   N D +  +++++   IQ+  +D+R   YK++
Sbjct: 171 --ILPDGRVIKVGGERFEAPEALFQPHLINVDGV-GVAELLFNTIQAADMDIRPDFYKHI 341

Query: 320 VLSGGSTMFRDFGRRLQRDLKRVVDARLKLSQELSGGRIKPKPVEVQVVTHHMQRYAVWF 379
           VLSGGSTM+     RL+R++K     +L L + L G   +    ++++     +++ V+ 
Sbjct: 342 VLSGGSTMYPGLPSRLEREIK-----QLYLERVLXGDTSRLSKFKIRIEDPPRRKHMVFL 506

Query: 380 GGSMLA----STPEFFQVCHTKKDYEEYGPSIC 408
           GGS+ A       +F+ +   + +YEE G  + 
Sbjct: 507 GGSVXADIMKDKDDFWMM---RSEYEEMGVKVL 596
>17032
          Length = 2938

 Score = 81.6 bits (200), Expect = 6e-16,   Method: Compositional matrix adjust.
 Identities = 34/40 (85%), Positives = 38/40 (95%)
 Frame = -1

Query: 379  FGGSMLASTPEFFQVCHTKKDYEEYGPSICRHNPVFGVMS 418
            FGGSMLASTPEF+QVCHTK DY+E+GPSICRHNPVFG M+
Sbjct: 2938 FGGSMLASTPEFYQVCHTKADYDEHGPSICRHNPVFGTMA 2819
>32273
          Length = 265

 Score = 79.3 bits (194), Expect = 3e-15,   Method: Compositional matrix adjust.
 Identities = 39/81 (48%), Positives = 57/81 (70%), Gaps = 1/81 (1%)
 Frame = -2

Query: 73  ATKWPIRHGIVEDWDLMERFMEQVVFK-YLRAEPEDHYFLMTEPPLNTPENREYLAEIMF 131
           + ++P+ HGIV+DW+ MER  + +  K  L+   E+H  L+TE PLN   NRE  AEI F
Sbjct: 258 SIRYPMEHGIVKDWNDMERIWQYIYSKDQLQTFSEEHPVLLTEAPLNPRRNREKAAEIFF 79

Query: 132 ESFNVPGLYIAVQAVLALAAS 152
           ++FNVP L+I++QAVL+L A+
Sbjct: 78  DTFNVPALFISMQAVLSLYAT 16
>11487
          Length = 771

 Score = 43.9 bits (102), Expect(2) = 2e-11,   Method: Compositional matrix adjust.
 Identities = 17/35 (48%), Positives = 24/35 (68%)
 Frame = -1

Query: 304 IQSCPIDVRRPLYKNVVLSGGSTMFRDFGRRLQRD 338
           I  C +D+R+ LY N VLSGG+TMF     R+Q++
Sbjct: 753 IMKCDVDIRKDLYANTVLSGGTTMFPGIADRMQKE 649

 Score = 42.4 bits (98), Expect(2) = 2e-11,   Method: Compositional matrix adjust.
 Identities = 18/35 (51%), Positives = 27/35 (77%)
 Frame = -2

Query: 373 QRYAVWFGGSMLASTPEFFQVCHTKKDYEEYGPSI 407
           ++Y+VW GGS+LAS   F Q+  +K++Y+E GPSI
Sbjct: 596 RKYSVWIGGSILASLSTFQQMWISKQEYDESGPSI 492
>18926
          Length = 478

 Score = 62.0 bits (149), Expect = 4e-10,   Method: Compositional matrix adjust.
 Identities = 37/124 (29%), Positives = 57/124 (45%), Gaps = 2/124 (1%)
 Frame = +1

Query: 285 PEFANPDFME--SISDVVDEVIQSCPIDVRRPLYKNVVLSGGSTMFRDFGRRLQRDLKRV 342
           P   NP       +  VV   +  C ID+R  LY  V+  GG+++ + F  RL RDL   
Sbjct: 61  PSSRNPKATPVLGVGHVVTTSVGMCDIDIRPSLYGGVIAVGGNSLIQGFTERLNRDLSNK 240

Query: 343 VDARLKLSQELSGGRIKPKPVEVQVVTHHMQRYAVWFGGSMLASTPEFFQVCHTKKDYEE 402
               ++L               +   +   +R++ W GGS+LAS   F Q+  +K++YEE
Sbjct: 241 TPPSMRLKI-------------IAAASTAERRFSSWIGGSILASLGSFQQMWVSKQEYEE 381

Query: 403 YGPS 406
            G S
Sbjct: 382 GGKS 393
>28457
          Length = 926

 Score = 31.6 bits (70), Expect = 0.71,   Method: Compositional matrix adjust.
 Identities = 15/39 (38%), Positives = 23/39 (58%), Gaps = 2/39 (5%)
 Frame = -2

Query: 271 VGYERF--LGPEIFFHPEFANPDFMESISDVVDEVIQSC 307
           VGY R   + P +FF P F+ P F  S S + ++V++ C
Sbjct: 925 VGYLRHVPISPSLFFRPSFSXPLFTASSSKLREKVLEIC 809
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|13994195|ref|NP_114074.1| protein phosphatase 1,
catalytic subunit, alpha [Mus musculus]
         (330 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

01173                                                                 591   e-169
06264                                                                 573   e-164
19040                                                                 297   3e-81
08242                                                                 276   6e-75
18336                                                                 170   7e-61
06084                                                                 229   9e-61
04295                                                                 157   5e-39
25536                                                                 151   4e-37
21146                                                                  64   6e-11
30980                                                                  63   1e-10
36367                                                                  55   3e-08
18967                                                                  54   8e-08
17953                                                                  41   8e-04
26290                                                                  27   8.3  
01222                                                                  27   9.5  
>01173
          Length = 2619

 Score =  591 bits (1524), Expect = e-169,   Method: Compositional matrix adjust.
 Identities = 287/304 (94%), Positives = 293/304 (96%)
 Frame = -1

Query: 26   KNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPES 85
            KNVQLTE+EIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPES
Sbjct: 2619 KNVQLTESEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPES 2440

Query: 86   NYLFLGDYVDRGKQSLETICLLLAYKIRYPENFFLLRGNHECASINRIYGFYDECKRRYN 145
            NYLFLGDYVDRGKQSLETICLLLAYKI+YPENFFLLRGNHECASINRIYGFYDECKRRYN
Sbjct: 2439 NYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYN 2260

Query: 146  IKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLL 205
            IKLWKTFTDCFNCLPIAAI+DEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLL
Sbjct: 2259 IKLWKTFTDCFNCLPIAAIIDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLL 2080

Query: 206  WSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVT 265
            WSDPDK+  GWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVT
Sbjct: 2079 WSDPDKETMGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVT 1900

Query: 266  LFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKNKGKYGQFSGLNPGGRPITPPRNS 325
            LFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADK K  YG   GLN  GRP+TPPR +
Sbjct: 1899 LFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKKKFPYG---GLNQ-GRPVTPPRGN 1732

Query: 326  AKAK 329
            AKAK
Sbjct: 1731 AKAK 1720
>06264
          Length = 999

 Score =  573 bits (1476), Expect = e-164,   Method: Compositional matrix adjust.
 Identities = 276/296 (93%), Positives = 283/296 (95%)
 Frame = -3

Query: 34  EIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDY 93
           EIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDY
Sbjct: 997 EIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDY 818

Query: 94  VDRGKQSLETICLLLAYKIRYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFT 153
           VDRG+QSLETICLLLAYKI+YPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFT
Sbjct: 817 VDRGRQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFT 638

Query: 154 DCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDV 213
           DCFNCLPIAAI+DEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDK+ 
Sbjct: 637 DCFNCLPIAAIIDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKET 458

Query: 214 QGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYC 273
            GWGE+DRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYC
Sbjct: 457 MGWGESDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYC 278

Query: 274 GEFDNAGAMMSVDETLMCSFQILKPADKNKGKYGQFSGLNPGGRPITPPRNSAKAK 329
           GEFDNAGAMMSVDETLMCSFQILKPADK K  YG  S     GRP+TPPR +AKAK
Sbjct: 277 GEFDNAGAMMSVDETLMCSFQILKPADKKKFPYGGLS----XGRPVTPPRGNAKAK 122
>19040
          Length = 452

 Score =  297 bits (761), Expect = 3e-81,   Method: Compositional matrix adjust.
 Identities = 140/150 (93%), Positives = 145/150 (96%)
 Frame = -3

Query: 36  RGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVD 95
           RGLCLKSREIFL QPILLELEAPL ICGDIHGQY DLLRLFEYGGFPP +NYLFLGDYVD
Sbjct: 450 RGLCLKSREIFLQQPILLELEAPLIICGDIHGQYTDLLRLFEYGGFPPAANYLFLGDYVD 271

Query: 96  RGKQSLETICLLLAYKIRYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDC 155
           RGKQSLETICLLLAYKI+YPENFFLLRGNHECASINRIYGFYDECKRRYN+KLWKTFTDC
Sbjct: 270 RGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNVKLWKTFTDC 91

Query: 156 FNCLPIAAIVDEKIFCCHGGLSPDLQSMEQ 185
           FNCLP+AAI+DEKIFCCHGGLSPDLQ MEQ
Sbjct: 90  FNCLPVAAIIDEKIFCCHGGLSPDLQGMEQ 1
>08242
          Length = 3368

 Score =  276 bits (707), Expect = 6e-75,   Method: Compositional matrix adjust.
 Identities = 128/257 (49%), Positives = 185/257 (71%), Gaps = 1/257 (0%)
 Frame = -1

Query: 44   EIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLET 103
            EI + +  +  +++P+ +CGDIHGQ+YDL  LF+ GG  P++NYLF+GD+VDRG  S+ET
Sbjct: 3368 EILVEESNVQRVDSPVTVCGDIHGQFYDLKELFKVGGDVPDTNYLFMGDFVDRGFYSVET 3189

Query: 104  ICLLLAYKIRYPENFFLLRGNHECASINRIYGFYDECKRRY-NIKLWKTFTDCFNCLPIA 162
              LLLA K+RYP+   L+RGNHE   I ++YGFYDEC R+Y +I +W+  T+ F+ L ++
Sbjct: 3188 FLLLLALKVRYPDRITLIRGNHESRQITQVYGFYDECLRKYGSITVWRYCTEIFDYLSLS 3009

Query: 163  AIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRG 222
            AI+D KIFC HGGLSP +Q+++QIR I R  +VP  G +CDLLWSDP+ D+QGWG + RG
Sbjct: 3008 AIIDGKIFCVHGGLSPSIQTLDQIRSIDRKQEVPHDGPMCDLLWSDPE-DMQGWGVSPRG 2832

Query: 223  VSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAM 282
              + FG++VV++F   + +DLICRAHQ+V +GY++     ++T++SAPNYC    N  A+
Sbjct: 2831 AGYLFGSDVVSQFNAANXIDLICRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAI 2652

Query: 283  MSVDETLMCSFQILKPA 299
            + +DE L   F I + A
Sbjct: 2651 LELDEHLQRDFTIFEAA 2601
>18336
          Length = 465

 Score =  170 bits (430), Expect(3) = 7e-61,   Method: Compositional matrix adjust.
 Identities = 85/111 (76%), Positives = 90/111 (81%)
 Frame = +2

Query: 26  KNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPES 85
           KNVQL+E +       SR I L       + +   ICGDIHGQYYDLLRLFEYGGFPPES
Sbjct: 2   KNVQLSEQK*EAYV*ISRNI-LESAYSFRIRSTT*ICGDIHGQYYDLLRLFEYGGFPPES 178

Query: 86  NYLFLGDYVDRGKQSLETICLLLAYKIRYPENFFLLRGNHECASINRIYGF 136
           NYLFLGDYVDRGKQSLETICLLLAYKI+YPENFFLLRGNHECASINRIYGF
Sbjct: 179 NYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGF 331

 Score = 74.3 bits (181), Expect(3) = 7e-61,   Method: Compositional matrix adjust.
 Identities = 32/34 (94%), Positives = 33/34 (97%)
 Frame = +1

Query: 137 YDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIF 170
           YDECKRRYNIKLWKTFTDCFNCLPIAAI+D KIF
Sbjct: 331 YDECKRRYNIKLWKTFTDCFNCLPIAAIIDVKIF 432

 Score = 28.9 bits (63), Expect(3) = 7e-61,   Method: Compositional matrix adjust.
 Identities = 11/12 (91%), Positives = 11/12 (91%)
 Frame = +3

Query: 170 FCCHGGLSPDLQ 181
            CCHGGLSPDLQ
Sbjct: 429 LCCHGGLSPDLQ 464
>06084
          Length = 1739

 Score =  229 bits (585), Expect = 9e-61,   Method: Compositional matrix adjust.
 Identities = 118/262 (45%), Positives = 165/262 (62%), Gaps = 1/262 (0%)
 Frame = -2

Query: 66   HGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIRYPENFFLLRGNH 125
            HGQ+YDL+ LF+ GG  P++NY+F+GD+VDRG  SLET  LLL  K ++P+   LLRGNH
Sbjct: 1738 HGQFYDLMELFKTGGEMPDTNYVFMGDFVDRGYFSLETFTLLLTLKAKWPDKIVLLRGNH 1559

Query: 126  ECASINRIYGFYDECKRRY-NIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSME 184
            E   I +IYGFYDEC+ +Y N   W+     F+ L IAAI+DE I C HGGLSPD+++++
Sbjct: 1558 ESRQITQIYGFYDECQTKYGNANAWRYCCRVFDLLTIAAIIDECILCVHGGLSPDIKTID 1379

Query: 185  QIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLI 244
            QIR I R  ++P +G  CDL+WSDP+ DV  W  + RG  + FGA+V A+F+  ++L LI
Sbjct: 1378 QIRTIERNQEIPHKGAFCDLVWSDPE-DVDTWAMSPRGAGWLFGAKVTAEFVASNNLKLI 1202

Query: 245  CRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKNKG 304
            CRAHQ+V +GY++    +LVT++SAPNYC    N  A++S  +      ++ K       
Sbjct: 1201 CRAHQLVHEGYKYMFDEKLVTVWSAPNYCYRCGNIAAVLSFTDAEHHEAKLFKAV----- 1037

Query: 305  KYGQFSGLNPGGRPITPPRNSA 326
                     P    + PPR   
Sbjct: 1036 ---------PDSERVIPPRTQT 998
>04295
          Length = 748

 Score =  157 bits (398), Expect = 5e-39,   Method: Compositional matrix adjust.
 Identities = 78/95 (82%), Positives = 86/95 (90%)
 Frame = -1

Query: 229 AEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDET 288
            +VV+KFL++HDLDLI RAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAG MMSVDET
Sbjct: 748 GDVVSKFLNRHDLDLITRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDET 569

Query: 289 LMCSFQILKPADKNKGKYGQFSGLNPGGRPITPPR 323
           LMCSFQILKP++K K KY Q+ GLN  GRPITPP+
Sbjct: 568 LMCSFQILKPSEK-KAKY-QYGGLN-SGRPITPPK 473
>25536
          Length = 486

 Score =  151 bits (381), Expect = 4e-37,   Method: Compositional matrix adjust.
 Identities = 65/127 (51%), Positives = 95/127 (74%), Gaps = 1/127 (0%)
 Frame = +1

Query: 29  QLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYL 88
           QL+EN+++ LC K++EI   +  + E++ P+ +CGD+HGQ++DL+ LF  GG  P++NYL
Sbjct: 106 QLSENQVKTLCEKAKEILSKESNVQEVKCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYL 285

Query: 89  FLGDYVDRGKQSLETICLLLAYKIRYPENFFLLRGNHECASINRIYGFYDECKRRY-NIK 147
           F+GDYVDRG  S+ET+ LL+A K+R+ +   +LRGNHE   I ++YGFYDEC R+Y N  
Sbjct: 286 FMGDYVDRGYYSVETVSLLVALKVRFRDRITILRGNHESRQITQVYGFYDECLRKYGNAN 465

Query: 148 LWKTFTD 154
           +WK FTD
Sbjct: 466 VWKYFTD 486
>21146
          Length = 408

 Score = 64.3 bits (155), Expect = 6e-11,   Method: Compositional matrix adjust.
 Identities = 37/78 (47%), Positives = 46/78 (58%), Gaps = 3/78 (3%)
 Frame = +3

Query: 198 QGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQ-VVEDGYE 256
           QG +CDLLWSDPD D  GWG + RG  +TFG ++   F H + L LI RAHQ V+E  + 
Sbjct: 114 QGPMCDLLWSDPD-DRGGWGISPRGAGYTFGQDISETFNHSNGLTLISRAHQLVMEVMFW 290

Query: 257 FFAKRQLVTLF--SAPNY 272
           F    Q   L+  S  NY
Sbjct: 291 FVTGMQTCLLYELSLQNY 344
>30980
          Length = 765

 Score = 63.2 bits (152), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 31/68 (45%), Positives = 41/68 (60%)
 Frame = +3

Query: 234 KFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSF 293
            F H + L LI RAHQ+V +GY +   R +VT+FSAPNYC    N  A+M +D+ L  SF
Sbjct: 3   TFNHSNGLTLISRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDALKYSF 182

Query: 294 QILKPADK 301
               PA +
Sbjct: 183 LQFDPAPR 206
>36367
          Length = 827

 Score = 55.5 bits (132), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 39/132 (29%), Positives = 66/132 (50%), Gaps = 20/132 (15%)
 Frame = +1

Query: 173 HGGL-SPDLQS---MEQIRRIMRPTDVP--DQGLLCDLLWSDPD-------------KDV 213
           HGG+ SP+ +    +E I +I  P   P  D  +  ++LWSDP              K+ 
Sbjct: 1   HGGIPSPENEGGGHLEAINKIPVPLSDPEVDSPMAWEILWSDPISVDLVSPEVLKDMKEH 180

Query: 214 QGWGENDR-GVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNY 272
            G+  N R G +  F    +  FL ++ L  + RAH+V E G++   + +L+T+FS+  Y
Sbjct: 181 HGFTFNSRRGTAHFFSCNALLAFLERNGLSHVIRAHEVQEVGFQVQQQGKLLTVFSSSRY 360

Query: 273 CGEFDNAGAMMS 284
           CG  + A  +++
Sbjct: 361 CGGSNEAACVLA 396
>18967
          Length = 440

 Score = 53.9 bits (128), Expect = 8e-08,   Method: Compositional matrix adjust.
 Identities = 23/46 (50%), Positives = 34/46 (73%)
 Frame = +2

Query: 241 LDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVD 286
           LDLICRAHQ+V +G ++  + +LVT++SAPNYC    N  A++S +
Sbjct: 2   LDLICRAHQLVNEGIKYMFEGKLVTVWSAPNYCYRCGNVAAILSFE 139
>17953
          Length = 626

 Score = 40.8 bits (94), Expect = 8e-04,   Method: Compositional matrix adjust.
 Identities = 20/56 (35%), Positives = 32/56 (57%), Gaps = 6/56 (10%)
 Frame = -2

Query: 236 LHKHDLDLICRAHQVVEDGYEFFAKRQ------LVTLFSAPNYCGEFDNAGAMMSV 285
           L +++L  I RAH+  + GY  + K Q      L+T+FSAPNY   ++N   ++S 
Sbjct: 625 LQQNNLLSIIRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKVQLLST 458
>26290
          Length = 559

 Score = 27.3 bits (59), Expect = 8.3,   Method: Compositional matrix adjust.
 Identities = 24/97 (24%), Positives = 36/97 (37%), Gaps = 6/97 (6%)
 Frame = -2

Query: 85  SNYLFLGDYVDRGKQSLETICLLLAYKIRYPENFFLLRGN--HECASINRIYGFYDECKR 142
           SN LFL   V +    L ++C +  + +R  EN F    N  H  + +   +   D    
Sbjct: 537 SNLLFLVLDVFKNVSGLWSVCKMKGFPVRNRENLFSPHTNAKHSLSMVEYFFSLSDSFLL 358

Query: 143 RYNIKLWKTFTDCFNCLP----IAAIVDEKIFCCHGG 175
            Y     K    C    P    +A++   K FC  G 
Sbjct: 357 AYMXG*SKPSCSCMRTAPMPVELASVRTTKSFCRSGN 247
>01222
          Length = 744

 Score = 27.3 bits (59), Expect = 9.5,   Method: Compositional matrix adjust.
 Identities = 16/55 (29%), Positives = 27/55 (49%), Gaps = 1/55 (1%)
 Frame = -2

Query: 119 FLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLP-IAAIVDEKIFCC 172
           F +  NH C S  ++Y   +    + NIKLW      + C+  +   V+E++F C
Sbjct: 707 FTIHSNHICRSRRKLYTEINPQHVKINIKLWHPTQFFYLCIMYVCRRVNEQVFVC 543
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|46195798|ref|NP_031864.2|
dolichyl-di-phosphooligosaccharide-protein glycotransferase [Mus
musculus]
         (441 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

07294                                                                 591   e-169
02987                                                                  30   2.1  
02457                                                                  29   3.8  
>07294
          Length = 1339

 Score =  591 bits (1524), Expect = e-169,   Method: Compositional matrix adjust.
 Identities = 280/408 (68%), Positives = 342/408 (83%)
 Frame = +3

Query: 28  SGPRTLVLLDNLNVRDTHSLFFRSLKDRGFELTFKTADDPSLSLIKYGEFLYDNLIIFSP 87
           +G RTLVL+DN ++R++HS+FFR+L+D GF+LTFK+ADD SL+L+KYGEFLYDNL+IFSP
Sbjct: 84  AGKRTLVLVDNWSIRESHSIFFRNLRDSGFDLTFKSADDGSLALVKYGEFLYDNLVIFSP 263

Query: 88  SVEDFGGNINVETISAFIDGGGSVLVAASSDIGDPLRELGSECGIEFDEEKTAVIDHHNY 147
           SVE+FGG ++V  I+ FIDGGG+VLVAASS+IGDPLREL +ECG+EFDEEKTAVIDH NY
Sbjct: 264 SVEEFGGTVDVPAITNFIDGGGNVLVAASSNIGDPLRELATECGVEFDEEKTAVIDHLNY 443

Query: 148 DVSDLGQHTLIVADTENLLKAPTIVGKSSLNPILFRGVGMVADPDNPLVLDILTGSSTSY 207
           DV+D G+HTLIVAD  NLL AP IVGK   +P LFRGVGMV+DP+NPLVL++L  S T+Y
Sbjct: 444 DVTDQGKHTLIVADPSNLLDAPMIVGKKGKSPFLFRGVGMVSDPENPLVLNVLHASPTAY 623

Query: 208 SFFPDKPITQYPHAVGRNTLLIAGLQARNNARVIFSGSLDFFSDAFFNSAVQKATPGAQR 267
           S  P + I ++PHAVG NTLLIAGLQARNNARV+F GSLDFFSD FF+S+VQ A  G Q+
Sbjct: 624 SHSPTEKIDEFPHAVGANTLLIAGLQARNNARVVFVGSLDFFSDEFFHSSVQNALKG-QK 800

Query: 268 YSQTGNYELAVALSRWVFKEEGVLRVGPVSHHRVGEMAPPNAYTVTDLVEYSIIIEQLSN 327
           + Q+GN ELA  L++WVF ++GVLRVG V+HHR G+  P  AY +   ++YSI IE+L N
Sbjct: 801 FPQSGNQELAQNLAQWVFHQKGVLRVGKVAHHRTGQKQPDPAYIINQDIDYSIQIEELVN 980

Query: 328 GKWVPFDGDDIQLEFVRIDPFVRTFLKRKGGKYSVQFKLPDVYGVFQFKVDYNRLGYTHL 387
           G+W PF+G+D+QLEFVRIDPFVRT LKRK G +   F LPDVYGVFQF VDYNR+GYT L
Sbjct: 981 GEWRPFNGEDVQLEFVRIDPFVRTILKRKNGLFYTSFTLPDVYGVFQFIVDYNRVGYTRL 1160

Query: 388 YSSTQVSVRPLQHTQYERFIPSAYPYYASAFSMMAGLFIFSIVFLHMK 435
           +S+TQVSV PLQHTQYER+IPSA+PYY+SAFSMM G+ IFS VFLH +
Sbjct: 1161FSTTQVSVWPLQHTQYERYIPSAFPYYSSAFSMMVGVVIFSFVFLHFR 1304
>02987
          Length = 2020

 Score = 30.0 bits (66), Expect = 2.1,   Method: Compositional matrix adjust.
 Identities = 14/44 (31%), Positives = 23/44 (52%)
 Frame = -3

Query: 307  PNAYTVTDLVEYSIIIEQLSNGKWVPFDGDDIQLEFVRIDPFVR 350
            P A  +  L  YSI I ++++  W  F+G  + L    + PF+R
Sbjct: 1856 PQAXNIEKLSSYSI*INKITHMIWXIFEGIYLHLXXEILAPFMR 1725
>02457
          Length = 934

 Score = 28.9 bits (63), Expect = 3.8,   Method: Compositional matrix adjust.
 Identities = 12/27 (44%), Positives = 17/27 (62%)
 Frame = +2

Query: 384 YTHLYSSTQVSVRPLQHTQYERFIPSA 410
           YT LYS   ++++ + HT Y  FI SA
Sbjct: 659 YTCLYSINNLALKKMMHTLYSHFIISA 739
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|74315975|ref|NP_081633.1| proteasome 26S non-ATPase
subunit 1 [Mus musculus]
         (953 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

32303                                                                 476   e-169
02455                                                                 116   4e-26
00896                                                                  68   1e-11
34335                                                                  47   3e-05
>32303
          Length = 1266

 Score =  476 bits (1224), Expect(3) = e-169,   Method: Compositional matrix adjust.
 Identities = 220/274 (80%), Positives = 250/274 (91%)
 Frame = -3

Query: 537 QETQHEKILRGLAVGIALVMYGRMEEADALIESLCRDKDPILRRSGMYTVAMAYCGSGNN 596
           + TQHEKILRGLAVGIAL MYGRMEEADAL+ESL RDKDPILR +GMYT+AMAYCGSGNN
Sbjct: 874 RTTQHEKILRGLAVGIALTMYGRMEEADALVESLTRDKDPILRWAGMYTLAMAYCGSGNN 695

Query: 597 KAIRRLLHVAVSDVNDDVRRAAVESLGFILFRTPEQCPSVVSLLSESYNPHVRYGAAMAL 656
           +AIRRLLHVAVSDVNDDVRR AV SLGF+LFRTPEQCPSVVSLLSESYNPHVR+GAAMAL
Sbjct: 694 QAIRRLLHVAVSDVNDDVRRVAVTSLGFLLFRTPEQCPSVVSLLSESYNPHVRFGAAMAL 515

Query: 657 GICCAGTGNKEAINLLEPMTNDPVNYVRQGALIASALIMIQQTEITCPKVNQFRQLYSKV 716
           GI CAG+G KEA+ LLEPMTNDPVNYVRQGALIASALI+IQ  E++CPKV  FRQLY+KV
Sbjct: 514 GIACAGSGLKEAMALLEPMTNDPVNYVRQGALIASALILIQHNEVSCPKVTHFRQLYAKV 335

Query: 717 INDKHDDVMAKFGAILAQGILDAGGHNVTISLQSRTGHTHMPSVVGVLVFTQFWFWFPLS 776
           I+DKH+DVMAKFGAILAQGI+DAGG N T+SLQSRTGHT+M +VVG+LVF QFW+W+PL+
Sbjct: 334 ISDKHEDVMAKFGAILAQGIIDAGGRNCTVSLQSRTGHTNMDAVVGLLVFCQFWYWYPLT 155

Query: 777 HFLSLAYTPTCVIGLNKDLKMPKVQYKSNCKPST 810
           HFLSLA++P C++GLN DLKMPKV   S+ +P +
Sbjct: 154 HFLSLAFSPACIVGLNADLKMPKV---SSSRPGS 62

 Score =  101 bits (252), Expect(3) = e-169,   Method: Composition-based stats.
 Identities = 45/56 (80%), Positives = 49/56 (87%)
 Frame = -1

Query: 407  SLGVIHKGHEKEALQLMATYLPKDTSPGSAYQEGGGLYALGLIHANHGGDIIDYLL 462
            SLG IH GHEKEAL LM++YLPKDT+ GSAY EGGGLYALGLIHANHGG I +YLL
Sbjct: 1266 SLGCIHHGHEKEALNLMSSYLPKDTTAGSAYSEGGGLYALGLIHANHGGQITEYLL 1099

 Score = 59.7 bits (143), Expect(3) = e-169,   Method: Compositional matrix adjust.
 Identities = 33/85 (38%), Positives = 40/85 (47%)
 Frame = -2

Query: 454  GGDIIDYLLNQLKNASNDIVRHXXXXXXXXXXXXXXRQDVYDLLKTNLYQDDXXXXXXXX 513
            GG        QLK+AS D+VRH              RQD+Y+ LK NLYQDD        
Sbjct: 1124 GGRSPSTSWGQLKDASTDMVRHGGCLGLGLAAMGTARQDIYEQLKFNLYQDDAVTGEAAG 945

Query: 514  XXXXXXXXXSKNAQAIEDMVGYAQE 538
                     +K+  AIEDMV YAQ+
Sbjct: 944  LAMGLVMLGTKSTPAIEDMVAYAQD 870
>02455
          Length = 832

 Score =  116 bits (291), Expect = 4e-26,   Method: Compositional matrix adjust.
 Identities = 49/82 (59%), Positives = 63/82 (76%)
 Frame = -1

Query: 755 THMPSVVGVLVFTQFWFWFPLSHFLSLAYTPTCVIGLNKDLKMPKVQYKSNCKPSTFAYP 814
           T+M +VVG+LVF QFW+W+PL+HFLSLA++P C++GLN DLKMPKV++KS+ KPS +AYP
Sbjct: 832 TNMDAVVGLLVFCQFWYWYPLTHFLSLAFSPACIVGLNADLKMPKVEFKSSGKPSLYAYP 653

Query: 815 APLXXXXXXXXXXXSTAVLSIT 836
            PL            TAVLSIT
Sbjct: 652 PPLEEKKNQTKEKVETAVLSIT 587

 Score = 69.3 bits (168), Expect = 7e-12,   Method: Compositional matrix adjust.
 Identities = 37/61 (60%), Positives = 46/61 (75%), Gaps = 1/61 (1%)
 Frame = -1

Query: 875 FQLLDNPARVMPAQLKVLSMTETCRYQPFKPLSIGGIIILKDTS-EDVEELVEPVAAHGP 933
           F+LL NPARVM  QL+VLS +E  RY+P K LS GGI+ILK+ + E+ E+LVE V A GP
Sbjct: 349 FELLSNPARVMKNQLRVLSSSEGSRYRPVKDLSHGGIVILKNVNPEEEEDLVEFVQAGGP 170

Query: 934 K 934
           K
Sbjct: 169 K 167
>00896
          Length = 2317

 Score = 68.2 bits (165), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 37/61 (60%), Positives = 46/61 (75%), Gaps = 1/61 (1%)
 Frame = -3

Query: 875  FQLLDNPARVMPAQLKVLSMTETCRYQPFKPLSIGGIIILKDTS-EDVEELVEPVAAHGP 933
            F+LL NPARVM  QL+VLS +E  RY+P K LS GGI+ILK+ + E+ E+LVE V A GP
Sbjct: 1595 FELLSNPARVMKNQLRVLSSSEGSRYRPVKDLSHGGIVILKNVNPEEEEDLVEFVQAGGP 1416

Query: 934  K 934
            K
Sbjct: 1415 K 1413
>34335
          Length = 561

 Score = 47.4 bits (111), Expect = 3e-05,   Method: Composition-based stats.
 Identities = 22/26 (84%), Positives = 23/26 (88%)
 Frame = +2

Query: 583 MYTVAMAYCGSGNNKAIRRLLHVAVS 608
           MYT  MAYCGSGNN+AIRRLLHV VS
Sbjct: 23  MYT--MAYCGSGNNQAIRRLLHVVVS 94
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|170932536|ref|NP_031942.2| Ddx19-like protein [Mus
musculus]
         (478 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

02498                                                                 325   e-168
01062                                                                 270   1e-72
09316                                                                 209   2e-54
00621                                                                 141   6e-34
07310                                                                 139   2e-33
19151                                                                 126   2e-29
00162                                                                 115   5e-26
00739                                                                 102   3e-22
01517                                                                  99   5e-21
08036                                                                  64   4e-20
19640                                                                  88   6e-20
02054                                                                  90   2e-18
34295                                                                  80   2e-15
14337                                                                  79   5e-15
22006                                                                  75   9e-14
31781                                                                  72   4e-13
31899                                                                  70   2e-12
11624                                                                  68   9e-12
00617                                                                  62   7e-10
12995                                                                  60   2e-09
39583                                                                  57   1e-08
17544                                                                  56   2e-08
33543                                                                  54   1e-07
10649                                                                  54   1e-07
19525                                                                  54   2e-07
17708                                                                  50   3e-06
31220                                                                  46   4e-05
11160                                                                  38   9e-05
30136                                                                  44   1e-04
06438                                                                  44   2e-04
33025                                                                  43   3e-04
03381                                                                  43   3e-04
04107                                                                  42   6e-04
11423                                                                  40   0.002
33083                                                                  36   0.038
12624                                                                  29   3.7  
>02498
          Length = 1955

 Score =  325 bits (834), Expect(2) = e-168,   Method: Compositional matrix adjust.
 Identities = 151/231 (65%), Positives = 190/231 (82%)
 Frame = +1

Query: 59  SLLNKLIRSNLVDNTNQVEVLQRDPSSPLYSVKSFEELRLKPQLLQGVYAMGFNRPSKIQ 118
           SLL KL+ S L+++   +EVL++DP+SPLYSVKSFE L LKPQLL+GVY MGFN PSKIQ
Sbjct: 37  SLLQKLLHSKLINSKTDIEVLRKDPNSPLYSVKSFEALNLKPQLLKGVYDMGFNAPSKIQ 216

Query: 119 ENALPMMLAEPPQNLIAQSQSGTGKTAAFVLAMLSRVEPADRYPQCLCLSPTYELALQTG 178
           E ALP++LA+PP N+IAQSQSGTGKTAAFVL MLSRV+ +  +PQCLCL+PTYELALQ G
Sbjct: 217 ETALPILLADPPVNMIAQSQSGTGKTAAFVLTMLSRVDISQTFPQCLCLAPTYELALQIG 396

Query: 179 KVIEQMGKFHPELKLAYAVRGNKLERGQKVSEQIVIGTPGTVLDWCSKLKFIDPKKIKVF 238
           +VIE+M K    L++ YAVRG ++ RG+ +SEQIVIGTPGTV+DW  + K +  +K++VF
Sbjct: 397 EVIEKMSKHMTGLEIRYAVRGERVNRGEVLSEQIVIGTPGTVMDWSHRFKALPLEKLRVF 576

Query: 239 VLDEADVMIATQGHQDQSIRIQRMLPRNCQMLLFSATFEDSVWKFAQKVVP 289
           VLDEADVMI+ QGHQDQS RIQ+ L   CQMLLFSAT++  V +FAQ+++P
Sbjct: 577 VLDEADVMISMQGHQDQSTRIQKRLSSGCQMLLFSATYDQVVMQFAQRIIP 729

 Score =  285 bits (730), Expect(2) = e-168,   Method: Compositional matrix adjust.
 Identities = 127/189 (67%), Positives = 161/189 (85%)
 Frame = +3

Query: 290 DPNIIKLKREEETLDTIKQYYVLCNNREEKFQALCNLYGAITIAQAMIFCHTRKTASWLA 349
           DP II LKREEE+LD IKQYY+ CN++EEK+ ALCN+YG+I++ Q+MIFCH R TA+WLA
Sbjct: 732 DPVIISLKREEESLDNIKQYYIDCNSQEEKYVALCNIYGSISVGQSMIFCHKRSTAAWLA 911

Query: 350 AELSKEGHQVALLSGEMMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVVINFDL 409
             ++ + H V LL+GE+ +EQRAA+I+RFREGKEKVL+TTNV ARGIDVE V+VV+NFDL
Sbjct: 912 ERMTADHHAVGLLTGELTIEQRAAIIKRFREGKEKVLITTNVSARGIDVEMVTVVVNFDL 1091

Query: 410 PVDKDGNPDNETYLHRIGRTGRFGKRGLAVNMVDSKHSMNILNRIQEHFNKKIERLDTDD 469
           PV +D  PD ETYLHRIGRTGRFGK G+A+NMVD+  SM I+  I++HF +KIE+LDT+D
Sbjct: 1092PVTQDWRPDCETYLHRIGRTGRFGKNGIAINMVDNSRSMAIMRSIEKHFGRKIEKLDTED 1271

Query: 470 LDEIEKIAN 478
           LDEIEKI++
Sbjct: 1272LDEIEKISS 1298
>01062
          Length = 2138

 Score =  270 bits (689), Expect = 1e-72,   Method: Compositional matrix adjust.
 Identities = 149/381 (39%), Positives = 238/381 (62%), Gaps = 7/381 (1%)
 Frame = -3

Query: 92   SFEELRLKPQLLQGVYAMGFNRPSKIQENALPMMLAEPPQNLIAQSQSGTGKTAAFVLAM 151
            +F+ + ++ +LL+G+YA GF +PS IQ+ A+  ++    +++IAQ+QSGTGKTA F +++
Sbjct: 2076 TFDNMGIREELLRGIYAYGFEKPSAIQQRAVKPIVK--GRDVIAQAQSGTGKTATFSISV 1903

Query: 152  LSRVEPADRYPQCLCLSPTYELALQTGKVIEQMGKFHPELKLAYAVRGN-------KLER 204
            L  ++   R  Q L LSPT ELA Q  KV+  +G +   ++    + G        KL+ 
Sbjct: 1902 LQCLDIQLRETQALILSPTRELATQIQKVMLALGDYM-NVQCHSCIGGTNIGEDIRKLDY 1726

Query: 205  GQKVSEQIVIGTPGTVLDWCSKLKFIDPKKIKVFVLDEADVMIATQGHQDQSIRIQRMLP 264
            GQ     IV GTPG V D   K + +  + IK+ +LDEAD M+  +G ++Q   + R LP
Sbjct: 1725 GQ----HIVSGTPGRVFDMI-KRRNLRTRSIKMMILDEADEML-NKGFKEQIYDVYRYLP 1564

Query: 265  RNCQMLLFSATFEDSVWKFAQKVVPDPNIIKLKREEETLDTIKQYYVLCNNREEKFQALC 324
               Q++L SAT    + +   K + DP  I +KR+E TL+ IKQ++V     E KF  LC
Sbjct: 1563 PATQVILISATLPHEILEMTNKFMTDPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLC 1384

Query: 325  NLYGAITIAQAMIFCHTRKTASWLAAELSKEGHQVALLSGEMMVEQRAAVIERFREGKEK 384
            +LY  +TI QA+IFC+T++   WL  ++ +    V+ + G+M  ++R A+++ FR G  +
Sbjct: 1383 DLYDTLTITQAVIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKEREAIMKVFRAGDSR 1204

Query: 385  VLVTTNVCARGIDVEQVSVVINFDLPVDKDGNPDNETYLHRIGRTGRFGKRGLAVNMVDS 444
            VL+TT+V ARGIDV+QVS+VIN+DLP ++      E Y+HRIGR+GRFG++G+A+N V  
Sbjct: 1203 VLITTDVWARGIDVQQVSLVINYDLPNNR------ELYIHRIGRSGRFGRKGVAINFV-K 1045

Query: 445  KHSMNILNRIQEHFNKKIERL 465
               + IL  I+++++ +I+ +
Sbjct: 1044 NDDIRILRDIEQYYSTQIDEM 982
>09316
          Length = 2312

 Score =  209 bits (533), Expect = 2e-54,   Method: Compositional matrix adjust.
 Identities = 130/400 (32%), Positives = 217/400 (54%), Gaps = 8/400 (2%)
 Frame = +2

Query: 80   QRDPSSPLYSVKS--FEELRLKPQLLQGVYAMGFNRPSKIQENALPMMLAEPPQNLIAQS 137
            ++D      S+ S  F +  LKP+LL+ +   GF  PS++Q   +P  +     +++ Q+
Sbjct: 806  KKDVKGTYVSIHSSGFRDFLLKPELLRAIIDCGFEHPSEVQHECIPQAILS--MDVLCQA 979

Query: 138  QSGTGKTAAFVLAMLSRVEPADRYPQCLCLSPTYELALQTGKVIEQMGKFHPELKLAYAV 197
            +SG GKTA FVLA L ++EP D     L ++ T ELA Q  K  E+  K+   +K+A   
Sbjct: 980  KSGMGKTAVFVLATLQQLEPVDGQVSVLVMAHTRELAFQISKEYERFSKYMNNVKIAVFF 1159

Query: 198  RGNKLERGQKV----SEQIVIGTPGTVLDWCSKLKFIDPKKIKVFVLDEADVMIATQGHQ 253
             G  +++ ++V       IV+GTPG  L   +K   ++ KKIK F+LDE D M+A    +
Sbjct: 1160 GGMSVKKDEEVLSKNCPHIVVGTPGR-LHALAKANNLNLKKIKHFILDECDKMLADLDMR 1336

Query: 254  DQSIRIQRMLPRNCQMLLFSATFEDSVWKFAQKVVPDPNIIKLKREEE-TLDTIKQYYVL 312
                 I R+ P   Q+++FSAT    +    +K + DP  + +  + + TL  ++Q+Y  
Sbjct: 1337 RDVQEIFRLTPHEKQVMMFSATLSKEIRPICKKFMQDPMEVYVDDDSKLTLHGLQQHY-- 1510

Query: 313  CNNRE-EKFQALCNLYGAITIAQAMIFCHTRKTASWLAAELSKEGHQVALLSGEMMVEQR 371
            C  ++ EK + L  L   +   Q +IF  +      L+  L ++      +  +M  E+R
Sbjct: 1511 CKLKDNEKNRKLFELLDVLEFNQVIIFVKSVPRCMALSQLLLEQNFPAIAIHRQMTQEER 1690

Query: 372  AAVIERFREGKEKVLVTTNVCARGIDVEQVSVVINFDLPVDKDGNPDNETYLHRIGRTGR 431
             +  ++F++ ++++LV TN+  RG+D+E+V++V N+D+P D D      TYLHR+ R GR
Sbjct: 1691 LSRYQQFKDFQKRILVATNLFGRGMDIERVNIVFNYDMPEDSD------TYLHRVARAGR 1852

Query: 432  FGKRGLAVNMVDSKHSMNILNRIQEHFNKKIERLDTDDLD 471
            FG +GLA+  V  ++   ILN +QE F   I  L  D++D
Sbjct: 1853 FGTKGLAITFVSDENDAKILNDVQERFEVNITEL-PDEID 1969
>00621
          Length = 2263

 Score =  141 bits (355), Expect = 6e-34,   Method: Compositional matrix adjust.
 Identities = 111/399 (27%), Positives = 198/399 (49%), Gaps = 40/399 (10%)
 Frame = +1

Query: 90  VKSFEELRLKPQLLQGVYAMGFNRPSKIQENALPMMLAEPPQNLIAQSQSGTGKTAAFVL 149
           ++ ++E  L   +++ +  +G+  P+ IQ  A+P+ L    +++I  +++G+GKTAAF++
Sbjct: 250 IRFWKESDLGADIMEVIDRVGYKEPTPIQMQAIPIGLQN--RDIIGVAETGSGKTAAFLI 423

Query: 150 AML---------SRVEPADRYPQCLCLSPTYELALQTGKVIEQMGKFHPEL--KLAYAVR 198
            +L          R+E AD+ P  + L+PT ELA Q   + E+  KF   L  ++   + 
Sbjct: 424 PLLVWIQSLPKIERLEDADQGPYAVILAPTRELAQQ---IEEETRKFGEGLGIRVVSVIG 594

Query: 199 G-NKLERGQKVSE--QIVIGTPGTVLDWCSKLKFIDPKKIKVFVLDEADVMIATQGHQDQ 255
           G ++ E+G K+ +  ++VI TPG ++D     +++   +    V+DEAD MI   G + +
Sbjct: 595 GISREEQGFKLQQGCEVVIATPGRMIDVLEN-RYLVLNQCTYVVMDEADRMI-NMGFEPE 768

Query: 256 SIRIQRMLP-------------------------RNCQMLLFSATFEDSVWKFAQKVVPD 290
             +I   LP                         +  Q ++F+AT    V + A+  +  
Sbjct: 769 VRKILDYLPVSNQKPDNDDAEDDLKMLQNFKSKHKYRQTVMFTATMPPQVERLARTFLRR 948

Query: 291 PNIIKLKREEETLDTIKQ-YYVLCNNREEKFQALCNLYGAITIAQAMIFCHTRKTASWLA 349
           P ++ +    + ++ ++Q  Y+L  +  EK + L  +  A      +IF + +K A  LA
Sbjct: 949 PTVVYIGNVGKPVERVEQIVYMLTES--EKRKKLIEVLNAGVDPPIIIFVNQKKGADVLA 1122

Query: 350 AELSKEGHQVALLSGEMMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVVINFDL 409
             L K G     L G    EQR   +   + G + ++V T+V  RGID++ VS+V+N+D+
Sbjct: 1123KSLEKMGFNATTLHGGKGQEQREYALASLKGGAKDIMVATDVAGRGIDIKDVSLVLNYDM 1302

Query: 410 PVDKDGNPDNETYLHRIGRTGRFGKRGLAVNMVDSKHSM 448
                     E Y HRIGRTGR GK G ++  +  + SM
Sbjct: 1303AR------TIEDYTHRIGRTGRAGKEGTSITFLTKEDSM 1401
>07310
          Length = 712

 Score =  139 bits (350), Expect = 2e-33,   Method: Compositional matrix adjust.
 Identities = 84/244 (34%), Positives = 139/244 (56%)
 Frame = +2

Query: 220 VLDWCSKLKFIDPKKIKVFVLDEADVMIATQGHQDQSIRIQRMLPRNCQMLLFSATFEDS 279
           +LD  +K + + P    + VLDEAD +++ Q  +     I   LP   Q+LL+SATF  S
Sbjct: 5   ILDLMNK-RLVKPDTCGILVLDEADKLLS-QDFKGMLDNIIAHLPPQRQILLYSATFPLS 178

Query: 280 VWKFAQKVVPDPNIIKLKREEETLDTIKQYYVLCNNREEKFQALCNLYGAITIAQAMIFC 339
           V +F +K + +P  I L  EE TL  + QYY     ++ K   L  L+  + I Q++IFC
Sbjct: 179 VEQFMKKYLKNPYEINLM-EELTLKGVTQYYAFVQEKQ-KVHCLNTLFSKLQINQSIIFC 352

Query: 340 HTRKTASWLAAELSKEGHQVALLSGEMMVEQRAAVIERFREGKEKVLVTTNVCARGIDVE 399
           ++ +    LA ++++ G+    +  +M  + R  V   FR+G  + LV +++  RGID++
Sbjct: 353 NSTQRVELLAKKITELGYSCYYIHAKMNQQHRNRVFHDFRQGLCRNLVCSDLFTRGIDIQ 532

Query: 400 QVSVVINFDLPVDKDGNPDNETYLHRIGRTGRFGKRGLAVNMVDSKHSMNILNRIQEHFN 459
            V+VVINFD P         ETYLHRIGR+GR+G  G+A+N++  +   + L++I++   
Sbjct: 533 AVNVVINFDFP------KHAETYLHRIGRSGRYGHLGVAINLITFEDRFS-LHKIEQELG 691

Query: 460 KKIE 463
            +I+
Sbjct: 692 TEIK 703
>19151
          Length = 625

 Score =  126 bits (317), Expect = 2e-29,   Method: Compositional matrix adjust.
 Identities = 56/89 (62%), Positives = 73/89 (82%)
 Frame = -3

Query: 384 KVLVTTNVCARGIDVEQVSVVINFDLPVDKDGNPDNETYLHRIGRTGRFGKRGLAVNMVD 443
           KVL+TTNV +RGID+EQV++V+NFDLP+D  GN D ETYLHRIGRTGRFGK G+A+N++D
Sbjct: 623 KVLITTNVLSRGIDIEQVTIVVNFDLPIDLRGNADCETYLHRIGRTGRFGKSGIAINLID 444

Query: 444 SKHSMNILNRIQEHFNKKIERLDTDDLDE 472
            + SMN+   I++HF K I  L+TD+ DE
Sbjct: 443 GEKSMNVCRAIEKHFQKDIVYLNTDNADE 357
>00162
          Length = 2322

 Score =  115 bits (287), Expect = 5e-26,   Method: Compositional matrix adjust.
 Identities = 91/300 (30%), Positives = 148/300 (49%), Gaps = 9/300 (3%)
 Frame = +3

Query: 163 QCLCLSPTYELALQTGKVIEQMGKFHPELKLAYAVRGNKLERGQKV--SEQIVIGTPGTV 220
           + L ++PT ELA Q  +V+ ++  FH +      + G  + R   +     IVI T G +
Sbjct: 141 EALIITPTRELAFQIYEVLNKIRTFH-DFSANLVIGGKFMWRETHLMGKTNIVICTVGRL 317

Query: 221 LDWCSKLKFIDPKKIKVFVLDEADVMIATQGHQDQSIRIQRMLPRNCQMLLFSATFEDSV 280
           L      +  D  ++KV VLDEAD ++ ++  QD    +  + PR  Q LLFSAT   SV
Sbjct: 318 LHHLESTQAFDVSELKVLVLDEADRIMDSKFAQDMDSIMSHLPPR--QTLLFSATQTMSV 491

Query: 281 WKFAQKVVPDPNIIKLKREEE--TLDTIKQYYVLCNNREEKFQALCNLYGAITIAQAMIF 338
              A+  + DP+ + + R  E  T   ++Q Y++C    EK   L +        + M+F
Sbjct: 492 KTLARLSLKDPSYVSVDRHAEYVTPTGLEQSYIVCE-LHEKLSLLYSFLKNHPNNKIMVF 668

Query: 339 CHTRKTASWLAAELSKE--GHQVALLSGEMMVEQRAAVIERFREGKEKVLVTTNVCARGI 396
             T K A ++   + +E  G  V +L G +   +R  +   F   +  +L+TT++  RG+
Sbjct: 669 LQTCKQARYVHTVIKRERPGMSVLVLHGGIPQLRRLDIYREFCRKQHVILITTDLACRGL 848

Query: 397 DVEQVSVVINFDLPVDKDGNPDNETYLHRIGRTGRFGKRGLAVNMV---DSKHSMNILNR 453
           D   V+ VI  D PVD +      TY+HR GRT RF   G A+ ++   + +H +  L+R
Sbjct: 849 DFPAVNWVIQLDCPVDVN------TYIHRAGRTARFECNGQALLVLLPSEEEHMVEALHR 1010
>00739
          Length = 1313

 Score =  102 bits (255), Expect = 3e-22,   Method: Compositional matrix adjust.
 Identities = 76/264 (28%), Positives = 131/264 (49%), Gaps = 6/264 (2%)
 Frame = +3

Query: 202 LERGQK--VSEQIVIGTPGTVLDWCSKLKFIDPKKIKVFVLDEADVMIATQ-GHQDQSIR 258
           +++GQ   V   IVI TPG + D          K++K  V+DEAD ++    G Q + I 
Sbjct: 12  MKQGQDLAVKPHIVISTPGRLADHIDSCDTFSLKRVKFLVMDEADRLLDDNFGAQLEPIL 191

Query: 259 IQRMLPRNCQMLLFSATFEDSVWKFAQKVVPDPNIIKLKREEETLDTIKQYYVLCNNREE 318
            +  LP   Q LLFSAT   +V      V+  P +   + E  T+D +++ YVL     +
Sbjct: 192 TR--LPSARQTLLFSATLSPTVNALRDSVLNKPFVWIQQSERATVDELQEDYVLVPASMK 365

Query: 319 K---FQALCNLYGAITIAQAMIFCHTRKTASWLAAELSKEGHQVALLSGEMMVEQRAAVI 375
                  L +       +  +IF  T K A  L   L K     A+L   +    R + +
Sbjct: 366 DAYMVHILDHWLKDHPRSSLIIFTXTCKYAQILGMMLEKLQFSCAVLHSMIPQRFRLSSL 545

Query: 376 ERFREGKEKVLVTTNVCARGIDVEQVSVVINFDLPVDKDGNPDNETYLHRIGRTGRFGKR 435
            RF+  + ++L++T+V +RG+D+  V ++IN ++P      P +  Y+HR+GRT R G+ 
Sbjct: 546 SRFKSNQTRILISTDVASRGLDIPTVDLIINHNIP----NRPRD--YVHRVGRTARAGRC 707

Query: 436 GLAVNMVDSKHSMNILNRIQEHFN 459
           G ++++V ++  + ++  I+ H N
Sbjct: 708 GQSISLV-TEFDIKLIKSIESHIN 776
>01517
          Length = 2605

 Score = 98.6 bits (244), Expect = 5e-21,   Method: Compositional matrix adjust.
 Identities = 73/215 (33%), Positives = 104/215 (48%), Gaps = 6/215 (2%)
 Frame = +2

Query: 238 FVLDEADVMIATQGHQDQSIRI---QRMLPRNC-QMLLFSATFEDSVWKFAQKVVPDPNI 293
            VLDEAD M+   G + Q  RI     M P    Q L+FSATF   +   A+  + +   
Sbjct: 50  LVLDEADRML-DMGFEPQIRRIVEKDTMPPTGQRQTLMFSATFPKEIQLLARDFLDNYIF 226

Query: 294 IKLKREEETLDTIKQYYVLCNNREEKFQALCNLYGAITIAQAM--IFCHTRKTASWLAAE 351
           + + R   T + I Q  V     E++   L  L  + T  +++  +F  T+K A  L   
Sbjct: 227 LAVGRVGSTSENITQKVVWVEEPEKRSFLLDLLMASGTGPESLTLVFVETKKGADSLEQF 406

Query: 352 LSKEGHQVALLSGEMMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVVINFDLPV 411
           L  E +    + G+    +R   +  F+ G   +LV T V ARG+D+  V  VINFDLP 
Sbjct: 407 LMYENYPATSIHGDRSQREREDALRVFKNGDRPILVATAVAARGLDIPNVRHVINFDLPS 586

Query: 412 DKDGNPDNETYLHRIGRTGRFGKRGLAVNMVDSKH 446
           D       E Y+HRIGRTGR G  GLA +  + K+
Sbjct: 587 DI------EEYVHRIGRTGRVGNLGLATSFFNDKN 673
>08036
          Length = 1226

 Score = 63.9 bits (154), Expect(2) = 4e-20,   Method: Compositional matrix adjust.
 Identities = 44/179 (24%), Positives = 90/179 (50%), Gaps = 1/179 (0%)
 Frame = +1

Query: 213 VIGTPGTVLDWCSKLKFIDPKKIKVFVLDEADVMIATQGHQDQSIRIQRMLPRNCQMLLF 272
           V+GTP  +L    +   ++   +++ V+DEAD ++ + GH+    ++   LPR  Q  L 
Sbjct: 1   VVGTPSRILAHL-RAGHLELHTVQMLVVDEAD-LVFSFGHEADMKKLMEELPRIYQAFLM 174

Query: 273 SATFEDSVWKFAQKVVPDPNIIKLKREEETLDT-IKQYYVLCNNREEKFQALCNLYGAIT 331
           SAT  + V    + V+ +P I+KLK  +    T + QY+V C   ++    +  L   + 
Sbjct: 175 SATLSEDVKALKKMVLHNPVILKLKESQLPESTQLTQYHVKCEVDDKFTLMVAVLKLGLV 354

Query: 332 IAQAMIFCHTRKTASWLAAELSKEGHQVALLSGEMMVEQRAAVIERFREGKEKVLVTTN 390
             ++++F ++  +   L   L   G    +L+ E+ V+ R  ++ +F EG   +++ ++
Sbjct: 355 RGKSILFVNSVDSCYKLKLFLEPFGIPACVLNSELPVKSRCHIVSQFNEGLYDIIIASD 531

 Score = 52.0 bits (123), Expect(2) = 4e-20,   Method: Compositional matrix adjust.
 Identities = 26/65 (40%), Positives = 39/65 (60%)
 Frame = +3

Query: 392 CARGIDVEQVSVVINFDLPVDKDGNPDNETYLHRIGRTGRFGKRGLAVNMVDSKHSMNIL 451
            ARGID + VS VINF+ P   D       Y+HR+GRT R  K+G A++++ S+H  +  
Sbjct: 609 VARGIDFQNVSNVINFEFPKTVDA------YIHRVGRTARGDKQGCALSLI-SRHENDQF 767

Query: 452 NRIQE 456
             ++E
Sbjct: 768 EAVEE 782
>19640
          Length = 456

 Score = 87.8 bits (216), Expect(2) = 6e-20,   Method: Composition-based stats.
 Identities = 44/101 (43%), Positives = 64/101 (63%)
 Frame = -1

Query: 337 IFCHTRKTASWLAAELSKEGHQVALLSGEMMVEQRAAVIERFREGKEKVLVTTNVCARGI 396
           IFC+TR+    L  E+S     V+ + G+M    R  ++++FR G  +VL+TT++ ARGI
Sbjct: 456 IFCNTRRKVDQLTQEMSSHNFTVSAMHGDMEQRDREVIMKQFRSGSSRVLITTDLLARGI 277

Query: 397 DVEQVSVVINFDLPVDKDGNPDNETYLHRIGRTGRFGKRGL 437
           DV+QVS+VIN+DLP ++      E Y+HRIGR G    R L
Sbjct: 276 DVQQVSLVINYDLPSNR------ENYIHRIGRGGVLVARVL 172

 Score = 27.7 bits (60), Expect(2) = 6e-20,   Method: Composition-based stats.
 Identities = 13/43 (30%), Positives = 25/43 (58%)
 Frame = -3

Query: 431 RFGKRGLAVNMVDSKHSMNILNRIQEHFNKKIERLDTDDLDEI 473
           RFG++G+A+N + +     IL  I++ ++  IE +  +  D I
Sbjct: 193 RFGRKGVAINFI-TDDDRRILKDIEQFYHTTIEEMPANIADLI 68
>02054
          Length = 1110

 Score = 89.7 bits (221), Expect = 2e-18,   Method: Compositional matrix adjust.
 Identities = 54/198 (27%), Positives = 101/198 (51%), Gaps = 1/198 (0%)
 Frame = -3

Query: 281 W-KFAQKVVPDPNIIKLKREEETLDTIKQYYVLCNNREEKFQALCNLYGAITIAQAMIFC 339
           W K  +  + DP  +++  + +T+DT++Q Y+    +  K   L ++   +     M+FC
Sbjct: 793 WPKLQRASLRDPVKVEVSNKYQTVDTLQQSYLFIPAKY-KDAYLVSILNELAGNSFMVFC 617

Query: 340 HTRKTASWLAAELSKEGHQVALLSGEMMVEQRAAVIERFREGKEKVLVTTNVCARGIDVE 399
            T      +A  L   G     L G+M   +R   + +F+     +L+ T+V +RG+D+ 
Sbjct: 616 STCANTQRVALLLRNLGFTAIPLHGQMSQAKRLGSLNKFKSKDRSILIATDVASRGLDIP 437

Query: 400 QVSVVINFDLPVDKDGNPDNETYLHRIGRTGRFGKRGLAVNMVDSKHSMNILNRIQEHFN 459
            V VV+N D+P        ++ Y+HR+GRT R G+ G A+  V S++ + +  RI+    
Sbjct: 436 HVDVVLNLDIPT------HSKDYMHRVGRTARAGRSGRAITFV-SQYDVELYQRIEHLIG 278

Query: 460 KKIERLDTDDLDEIEKIA 477
           KK+    T+  D++ ++A
Sbjct: 277 KKLSEYPTEK-DQVMQLA 227

 Score = 48.9 bits (115), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 27/82 (32%), Positives = 41/82 (50%)
 Frame = -2

Query: 211 QIVIGTPGTVLDWCSKLKFIDPKKIKVFVLDEADVMIATQGHQDQSIRIQRMLPRNCQML 270
            I+I TPG ++D     K    + +K  V+DEAD  I     QD+  +I +++PR     
Sbjct: 998 HIIIATPGRLVDHLENTKGFSLRALKFLVMDEAD-RILDMNFQDEVDKILKVIPRERNTY 822

Query: 271 LFSATFEDSVWKFAQKVVPDPN 292
           LFSAT  + V K    +   P+
Sbjct: 821 LFSATMTNKVAKTTASITEGPS 756
>34295
          Length = 694

 Score = 79.7 bits (195), Expect = 2e-15,   Method: Compositional matrix adjust.
 Identities = 45/142 (31%), Positives = 75/142 (52%)
 Frame = -1

Query: 328 GAITIAQAMIFCHTRKTASWLAAELSKEGHQVALLSGEMMVEQRAAVIERFREGKEKVLV 387
           G   I   MIF +T+K    L+  L+    +   L G M  ++R + + RF+    + L+
Sbjct: 556 GE*KIPNVMIFTNTKKYCQLLSMTLTNMEIENVCLHGFMRQKERVSALSRFKSNHIRTLI 377

Query: 388 TTNVCARGIDVEQVSVVINFDLPVDKDGNPDNETYLHRIGRTGRFGKRGLAVNMVDSKHS 447
            T+V ARG+D+  V +VIN  LP      P  + Y+HR+GRT R G++G+A+++      
Sbjct: 376 ATDVAARGLDIPSVQLVINHMLP----RTP--KEYIHRVGRTARAGRKGVAISIFRFPRD 215

Query: 448 MNILNRIQEHFNKKIERLDTDD 469
           + +L  I+E  N K+     D+
Sbjct: 214 LELLGAIEEEINTKLTEHPIDE 149
>14337
          Length = 693

 Score = 78.6 bits (192), Expect = 5e-15,   Method: Compositional matrix adjust.
 Identities = 46/141 (32%), Positives = 73/141 (51%), Gaps = 3/141 (2%)
 Frame = +2

Query: 319 KFQALCNLYGAITIAQAMIFCHTRKTASWLAAELSKEGHQVALLSGEMMVEQRAAVIERF 378
           K  A+ NL+        ++F  +++ A  L +E   + H+V  +  +    +R A +  F
Sbjct: 17  KLMAMRNLFTEGITPPVLVFVQSKQRAKELYSEFMFDKHKVDAIHADKPQAERDATVRAF 196

Query: 379 REGKEKVLVTTNVCARGIDVEQVSVVINFDLPVDKDGNPDNETYLHRIGRTGRFGKRGLA 438
            EG+  VLV T +  RGID + +++VIN+D P +        +Y+HRIGRTGR G  G A
Sbjct: 197 TEGRVWVLVCTELMGRGIDFKGINLVINYDFPTNA------VSYIHRIGRTGRAGVPGRA 358

Query: 439 VNMV---DSKHSMNILNRIQE 456
           +      D  H  +I N I+E
Sbjct: 359 ITFFTEQDVTHLRSIANIIKE 421
>22006
          Length = 3414

 Score = 74.7 bits (182), Expect = 9e-14,   Method: Compositional matrix adjust.
 Identities = 48/135 (35%), Positives = 83/135 (61%), Gaps = 4/135 (2%)
 Frame = +2

Query: 114  PSKIQENALPMMLAEPPQNLIAQSQSGTGKTAAFVLAMLSRVE-PADRYPQCLCLSPTYE 172
            P+ IQ   +P+++    ++++A +++G+GKTAAF++ ML R++  + +  + L LSPT E
Sbjct: 3005 PTPIQRKTIPVIMEG--KDMVAMARTGSGKTAAFLVPMLERLKMHSSKGARALILSPTRE 3178

Query: 173  LALQTGKVIEQMGKFHPELKLAYAVRGNKLERGQKVSEQ---IVIGTPGTVLDWCSKLKF 229
            LALQT K  +++GKF  +L+ A  + G+++E       Q   I+I TPG +L    ++K 
Sbjct: 3179 LALQTLKFTKELGKFL-DLRAAVILGGDRMEDQFSALHQNPDIIIATPGRLLHVLVEMK- 3352

Query: 230  IDPKKIKVFVLDEAD 244
               K++   V DEAD
Sbjct: 3353 KSLKEVIYVVFDEAD 3397
>31781
          Length = 416

 Score = 72.4 bits (176), Expect = 4e-13,   Method: Composition-based stats.
 Identities = 30/60 (50%), Positives = 44/60 (73%), Gaps = 1/60 (1%)
 Frame = -2

Query: 281 WKFAQKVVP-DPNIIKLKREEETLDTIKQYYVLCNNREEKFQALCNLYGAITIAQAMIFC 339
           W    K  P +P  I+L+REEE+LD I+QYY+ C    +K++ALCN+YG+I++ Q+MIFC
Sbjct: 307 WSSLAKSSPGNPVTIRLRREEESLDNIQQYYIRCRTLSDKYRALCNIYGSISVGQSMIFC 128

 Score = 62.4 bits (150), Expect = 4e-10,   Method: Composition-based stats.
 Identities = 46/153 (30%), Positives = 73/153 (47%), Gaps = 17/153 (11%)
 Frame = -3

Query: 246 MIATQGHQDQSIRIQRMLPRNCQMLLFSATFEDSVWKFAQKVVPDPNIIKLKREEETLDT 305
           MI+ QGHQD S RI R L       + +A     V +    V         + +   L+T
Sbjct: 414 MISMQGHQDSSTRIHRHLSAG----MSNAAVLGHVRRLCDGV---------RSQNHPLET 274

Query: 306 IKQYYVLCNNREEKFQALCNLY------------GAITIAQAMIF-----CHTRKTASWL 348
           + ++   C+ R+  +    +               A ++A +++         R TASWL
Sbjct: 273 L*RF--ACDGRKSLWTTSSSTTFAAAH*ATSTARSATSMAVSLLVRA*SSVKKRSTASWL 100

Query: 349 AAELSKEGHQVALLSGEMMVEQRAAVIERFREG 381
           A+++S + H VALL+GE+ +EQRAA+I RFR G
Sbjct: 99  ASKMSDDHHAVALLTGELSIEQRAAIIHRFRNG 1
>31899
          Length = 453

 Score = 70.1 bits (170), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 42/107 (39%), Positives = 56/107 (52%)
 Frame = -1

Query: 93  FEELRLKPQLLQGVYAMGFNRPSKIQENALPMMLAEPPQNLIAQSQSGTGKTAAFVLAML 152
           F  L L   +L G+   GF RPS IQ  A+P  L     +LI Q++SGTGKT  F +  L
Sbjct: 339 FASLLLSKPVLNGLKNAGFERPSPIQLKAIP--LGRCGLDLIVQAKSGTGKTCVFSVVAL 166

Query: 153 SRVEPADRYPQCLCLSPTYELALQTGKVIEQMGKFHPELKLAYAVRG 199
             +E   R  Q L L+PT E+ALQ  +VI  +G     L+    + G
Sbjct: 165 EGIETTARSTQVLVLAPTREIALQIWEVINSIGSAMSGLQCHTFIGG 25
>11624
          Length = 2257

 Score = 67.8 bits (164), Expect = 9e-12,   Method: Compositional matrix adjust.
 Identities = 34/101 (33%), Positives = 60/101 (59%)
 Frame = -1

Query: 356 GHQVALLSGEMMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVVINFDLPVDKDG 415
           G  V   S  +  E+R  ++++F +GK  +LV ++  ARG+DV+ V  VI++D P     
Sbjct: 829 GLSVKEFSSRLPGERRKKILKQFSKGKIDLLVCSDAMARGMDVDNVKYVISYDNP----- 665

Query: 416 NPDNETYLHRIGRTGRFGKRGLAVNMVDSKHSMNILNRIQE 456
            P  +TY+HR+GRT R G+ G A+++++ K   +    ++E
Sbjct: 664 -PYIKTYIHRVGRTARAGRAGTAISLLEKKEFFHFKQMMRE 545

 Score = 34.3 bits (77), Expect = 0.10,   Method: Compositional matrix adjust.
 Identities = 33/134 (24%), Positives = 61/134 (45%), Gaps = 16/134 (11%)
 Frame = -3

Query: 130  PQNLIAQSQSGTGKTAAFVLAMLS----RVEPADRYPQCLCLSPTYELALQTGKVIEQMG 185
            P+++   + +G+GKT A+ L ++     R+ P  R    + + P  +LA Q  +V     
Sbjct: 1817 PRDICVSAPTGSGKTLAYTLPIIQCLKQRMVPHVR---AVIVLPVRDLAEQVYQVFCHYC 1647

Query: 186  KFHPELKLAYAVRGN--KLERGQKVSEQ----------IVIGTPGTVLDWCSKLKFIDPK 233
               P LK+   V      +E+   V ++          I++ TPG ++D  +     D  
Sbjct: 1646 ADTP-LKVGIVVGKTVFNVEQDTLVKKRYGGVYHSVIDILVATPGRLVDHINSTPGFDLS 1470

Query: 234  KIKVFVLDEADVMI 247
             ++  V+DEAD M+
Sbjct: 1469 HLRFLVIDEADRMM 1428
>00617
          Length = 1505

 Score = 61.6 bits (148), Expect = 7e-10,   Method: Compositional matrix adjust.
 Identities = 27/89 (30%), Positives = 57/89 (64%)
 Frame = -3

Query: 371  RAAVIERFREGKEKVLVTTNVCARGIDVEQVSVVINFDLPVDKDGNPDNETYLHRIGRTG 430
            R + + RF+  + ++L++T+V +RG+D+  V ++IN ++P      P +  Y+HR+GRT 
Sbjct: 1440 RLSSLSRFKSNQTRILISTDVASRGLDIPTVDLIINHNIP----NRPRD--YVHRVGRTA 1279

Query: 431  RFGKRGLAVNMVDSKHSMNILNRIQEHFN 459
            R G+ G ++++V ++  + ++  I+ H N
Sbjct: 1278 RAGRCGQSISLV-TEFDIKLIKSIESHIN 1195
>12995
          Length = 1072

 Score = 60.1 bits (144), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 36/153 (23%), Positives = 73/153 (47%), Gaps = 1/153 (0%)
 Frame = +3

Query: 291 PNIIKLKREEETLDTIKQYYVLCNNREEKFQALCNLYGAITIAQ-AMIFCHTRKTASWLA 349
           P +++L  + +    ++  ++ C   +++   L  L   I+     ++F  T+    +L 
Sbjct: 3   PTLVRLDVDSKLSAQLQMSFLSCRADDKEAMLLYLLRDVISENDLTVVFVATKHHVEYLN 182

Query: 350 AELSKEGHQVALLSGEMMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVVINFDL 409
             L+K G     +   +    R   + +F   + KV++ T++ ARGID+ Q+  V+NF  
Sbjct: 183 TLLTKCGIACTYIYSSLDQTARKIHVAKFTHKQVKVMLVTDLAARGIDIPQLDNVVNFHF 362

Query: 410 PVDKDGNPDNETYLHRIGRTGRFGKRGLAVNMV 442
           P         + ++HR+GR  R G+ G A ++V
Sbjct: 363 PAKA------KLFVHRVGRVARAGRSGTAYSLV 443
>39583
          Length = 234

 Score = 57.0 bits (136), Expect = 1e-08,   Method: Composition-based stats.
 Identities = 27/64 (42%), Positives = 41/64 (64%)
 Frame = -3

Query: 370 QRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVVINFDLPVDKDGNPDNETYLHRIGRT 429
           QR   ++RF+EG+  VL+ T++ +RG+D+E V  VINF +P         + Y+HR+GRT
Sbjct: 175 QRLEALKRFKEGEIDVLLATDLASRGLDIEGVKTVINFTMPSTL------KHYVHRVGRT 14

Query: 430 GRFG 433
            R G
Sbjct: 13  ARAG 2
>17544
          Length = 1047

 Score = 56.2 bits (134), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 38/109 (34%), Positives = 60/109 (55%), Gaps = 17/109 (15%)
 Frame = +2

Query: 85  SPLYSVKSFEELRLKPQLLQGVYAMGFNRPSKIQENALPMMLAEPPQNLIAQSQSGTGKT 144
           SP   + SFEE  L   +   +    +N+P+ +Q+ ALP++L +  ++L+A +Q+G+GKT
Sbjct: 614 SPPPHINSFEECTLGEIIRNNIVLSKYNKPTPVQKFALPIVLGK--RDLMACAQTGSGKT 787

Query: 145 AAFVLAMLSRV---EPADR--------------YPQCLCLSPTYELALQ 176
           AAF+L +L++V    P                 YP  L L+PT ELA Q
Sbjct: 788 AAFLLPILNQVYENGPTPEALQQNQSRGYRRKMYPIALILAPTRELASQ 934
>33543
          Length = 471

 Score = 54.3 bits (129), Expect = 1e-07,   Method: Composition-based stats.
 Identities = 22/45 (48%), Positives = 30/45 (66%)
 Frame = +3

Query: 421 TYLHRIGRTGRFGKRGLAVNMVDSKHSMNILNRIQEHFNKKIERL 465
           TYLHR+GR GRFG RGLA+  V ++   ++LN +QE F   +  L
Sbjct: 3   TYLHRVGRAGRFGTRGLAITFVSNETEADVLNSVQERFEVSVTDL 137
>10649
          Length = 472

 Score = 54.3 bits (129), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 33/101 (32%), Positives = 53/101 (52%), Gaps = 3/101 (2%)
 Frame = +1

Query: 356 GHQVALLSGEMMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVVINFDLPVDKDG 415
           G  V +L G +   +R  +   F   +  +L+TT++  RG+D   V+ VI  D PVD + 
Sbjct: 64  GMSVLVLHGGIPQLRRLDIYREFCRKQHVILITTDLACRGLDFPAVNWVIQLDCPVDVN- 240

Query: 416 NPDNETYLHRIGRTGRFGKRGLAVNMV---DSKHSMNILNR 453
                TY+HR GRT RF   G A+ ++   + +H +  L+R
Sbjct: 241 -----TYIHRAGRTARFECNGQALLVLLPSEEEHMVEALHR 348
>19525
          Length = 585

 Score = 53.5 bits (127), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 39/123 (31%), Positives = 61/123 (49%), Gaps = 3/123 (2%)
 Frame = +2

Query: 165 LCLSPTYELALQTGKVIEQMGKFHPELKLAYAVRGNKL---ERGQKVSEQIVIGTPGTVL 221
           L L PT ELA+Q  +V +Q+ ++  ++ +  A  G  +   E   ++   IV+ TPG ++
Sbjct: 23  LVLVPTRELAVQVYQVGQQISQY-TKISICLAAGGLDIKGQEAALRLCPDIVVATPGRLI 199

Query: 222 DWCSKLKFIDPKKIKVFVLDEADVMIATQGHQDQSIRIQRMLPRNCQMLLFSATFEDSVW 281
           D            +++ VLDEAD M+  +    Q   I RM     Q +LFSAT  D+V 
Sbjct: 200 DHLHNAPNFTIAHVEILVLDEADRML-DEYFAAQMTEIIRMCNFQRQTMLFSATMSDAVQ 376

Query: 282 KFA 284
             A
Sbjct: 377 DLA 385
>17708
          Length = 882

 Score = 49.7 bits (117), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 29/101 (28%), Positives = 59/101 (58%), Gaps = 7/101 (6%)
 Frame = +1

Query: 129 PPQNLIAQSQSGTGKTAAFVLAMLSRVEPADRYPQ----CLCLSPTYELALQTGKVIEQM 184
           P ++L+  +++G+GKT AF++  +  +      P+    C+ +SPT EL++QT  V+ ++
Sbjct: 547 PHRDLMGAAKTGSGKTLAFLIPAIELMYKLKFMPRNGTGCIIISPTRELSMQTFNVLTEL 726

Query: 185 GKFHPE---LKLAYAVRGNKLERGQKVSEQIVIGTPGTVLD 222
            K+H     L +    R +++++ +K    I++ TPG +LD
Sbjct: 727 LKYHHHTFGLIMGGVNRHDEVKKLKK-GVNIIVATPGRLLD 846
>31220
          Length = 818

 Score = 45.8 bits (107), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 29/96 (30%), Positives = 48/96 (50%)
 Frame = +2

Query: 350 AELSKEGHQVALLSGEMMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVVINFDL 409
           ++ ++  + + + S E M+E+     +R    K K     +  +RGID + V+ VINFD 
Sbjct: 47  SQFNRGTYDIIIASDEHMLEKPDG*KQR----KSKHTDHESSASRGIDFQGVNNVINFDF 214

Query: 410 PVDKDGNPDNETYLHRIGRTGRFGKRGLAVNMVDSK 445
           P+D        +Y+HR GRT R    G  ++ V  K
Sbjct: 215 PLDV------TSYIHRAGRTARGNNTGSVLSFVSVK 304
>11160
          Length = 646

 Score = 38.1 bits (87), Expect(2) = 9e-05,   Method: Compositional matrix adjust.
 Identities = 44/184 (23%), Positives = 80/184 (43%), Gaps = 12/184 (6%)
 Frame = -1

Query: 200 NKLERGQKVSEQIVIGTPGTVLDWCSKLK-----FIDPKKIKVFVLDEADVMIATQGHQD 254
           + + +  K    I+I TPG + D  S+ +         K ++V VLDEAD ++   G + 
Sbjct: 628 HDISKFMKSGGSILIATPGRLDDLFSRKESGFNLAASVKALEVLVLDEADRLL-DMGFEA 452

Query: 255 QSIRIQRMLPRNCQMLLFSATFEDSVWKFAQKVVPDPNIIKLKR-------EEETLDTIK 307
               I   LP+  +  LFSAT  D V    +  + +P  + +K        ++ T  T+ 
Sbjct: 451 SINTILGHLPKLRRTGLFSATQTDEVENLIRAGLRNPLRVTVKEKKLAGEADQRTPSTLS 272

Query: 308 QYYVLCNNREEKFQALCNLYGAITIAQAMIFCHTRKTASWLAAELSKEGHQVALLSGEMM 367
            YY++    EEKF  L          + ++F  T     + +  L++    + +LS    
Sbjct: 271 NYYMIVEA-EEKFSQLVKFLKTHHRDKLLLFFSTCACVDYFSMCLTQLLKHMQVLSIHSK 95

Query: 368 VEQR 371
           ++Q+
Sbjct: 94  MKQK 83

 Score = 25.4 bits (54), Expect(2) = 9e-05,   Method: Compositional matrix adjust.
 Identities = 11/24 (45%), Positives = 15/24 (62%)
 Frame = -3

Query: 374 VIERFREGKEKVLVTTNVCARGID 397
           V  +FR     +LV T+V ARG+D
Sbjct: 74  VFAKFRSITSGLLVCTDVMARGVD 3
>30136
          Length = 524

 Score = 44.3 bits (103), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 27/101 (26%), Positives = 51/101 (50%), Gaps = 5/101 (4%)
 Frame = +2

Query: 90  VKSFEELRLKPQLLQGVYAMGFNRPSKIQENALPMMLAEPPQNLIAQSQSGTGKTAAFVL 149
           ++ F E  L   +++ +   G+  P+ IQ    P+ ++    N +  +++G+GKT  ++L
Sbjct: 128 IQDFAEAYLPDYVIKEIRRQGYKSPTPIQAQGWPIAMSG--ANFVGIAKTGSGKTLGYIL 301

Query: 150 AMLSRV---EPADRY--PQCLCLSPTYELALQTGKVIEQMG 185
             +  +   +P  R   P  L L+PT ELA Q  +V  + G
Sbjct: 302 PAIVHINNQQPLQRGEGPIALVLAPTRELAQQIQQVATEFG 424
>06438
          Length = 989

 Score = 43.5 bits (101), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 25/70 (35%), Positives = 38/70 (54%), Gaps = 3/70 (4%)
 Frame = +1

Query: 387 VTTNVCARGIDVEQVSVVINFDLPVDKDGNPDNETYLHRIGRTGRFGKRGLAVNMV---D 443
           +T  +  RG+D   V+ VI  D PVD +      TY+HR GRT RF   G A+ ++   +
Sbjct: 25  LTVTLACRGLDFPAVNWVIQLDCPVDVN------TYIHRAGRTARFECNGQALLVLLPSE 186

Query: 444 SKHSMNILNR 453
            +H +  L+R
Sbjct: 187 EEHMVEALHR 216
>33025
          Length = 558

 Score = 42.7 bits (99), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 40/155 (25%), Positives = 70/155 (45%), Gaps = 3/155 (1%)
 Frame = +3

Query: 188 HPELKLAYAVRGNKLERGQKVSEQIVIGTPGTVLDWCSKLKFIDPKKIKVFVLDEADVMI 247
           HP +      R  +  R  K    +V+GTPG +LD+    + I   K +  +LDEAD M+
Sbjct: 45  HPSVVYGATDRRYQKSRIMK-GANLVVGTPGRLLDFIGD-QTISLGKCQYLILDEADRML 218

Query: 248 --ATQGHQDQSIRIQRMLPRNC-QMLLFSATFEDSVWKFAQKVVPDPNIIKLKREEETLD 304
               +    + +    M P+   Q L+FSATF++ + + A   + D   I +        
Sbjct: 219 DMGFEPEIRKLVDTHGMPPKTQRQTLMFSATFKEDIQRLAGDFLNDYLFITVGIVGGACS 398

Query: 305 TIKQYYVLCNNREEKFQALCNLYGAITIAQAMIFC 339
            + Q + L  +R +K   LC +   +  A+++  C
Sbjct: 399 DVTQTF-LEVDRLQKRDHLCEILNEMGTAKSVGVC 500
>03381
          Length = 1206

 Score = 42.7 bits (99), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 18/50 (36%), Positives = 30/50 (60%)
 Frame = +3

Query: 396 IDVEQVSVVINFDLPVDKDGNPDNETYLHRIGRTGRFGKRGLAVNMVDSK 445
           +D+  +  V+N+D+  D D      T+ HR+GRTGR G++G A  ++  K
Sbjct: 3   LDIPHIRTVVNYDVARDID------THTHRVGRTGRAGEKGSAYTLITDK 134
>04107
          Length = 2502

 Score = 42.0 bits (97), Expect = 6e-04,   Method: Compositional matrix adjust.
 Identities = 27/98 (27%), Positives = 46/98 (46%), Gaps = 2/98 (2%)
 Frame = +1

Query: 334 QAMIFCHTRKTASWLAAELSKEGHQVALLSGEMMVEQRAAVIERFREGKE--KVLVTTNV 391
           + +IF    K    L A L+  GH+   L G   VEQR A+++RF   K     +++T  
Sbjct: 676 RVLIFTQMTKMLDVLEAFLNYHGHRYLRLDGTTKVEQRQALMDRFNADKRIFCFILSTRS 855

Query: 392 CARGIDVEQVSVVINFDLPVDKDGNPDNETYLHRIGRT 429
              G+++     V+ +D   +   +   +   HRIG+T
Sbjct: 856 GGIGVNLTGADTVVFYDSDWNPTMDAQAQDRCHRIGQT 969
>11423
          Length = 1434

 Score = 40.0 bits (92), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 19/57 (33%), Positives = 33/57 (57%)
 Frame = -2

Query: 400  QVSVVINFDLPVDKDGNPDNETYLHRIGRTGRFGKRGLAVNMVDSKHSMNILNRIQE 456
            Q   VI++D P      P  +TY+HR+GRT R G+ G A+++++ K   +    ++E
Sbjct: 1403 QRKYVISYDNP------PYIKTYIHRVGRTARAGRAGTAISLLEKKEFFHFKQMMRE 1251
>33083
          Length = 1931

 Score = 35.8 bits (81), Expect = 0.038,   Method: Compositional matrix adjust.
 Identities = 14/38 (36%), Positives = 24/38 (63%)
 Frame = +1

Query: 394 RGIDVEQVSVVINFDLPVDKDGNPDNETYLHRIGRTGR 431
           RG+D+ QV  ++ +D P       +++ Y+HR+GRT R
Sbjct: 1   RGLDIPQVDWIVQYDPP------DESKEYIHRVGRTAR 96
>12624
          Length = 589

 Score = 29.3 bits (64), Expect = 3.7,   Method: Compositional matrix adjust.
 Identities = 14/29 (48%), Positives = 18/29 (62%)
 Frame = +2

Query: 373 AVIERFREGKEKVLVTTNVCARGIDVEQV 401
           AV E FR+G+EKVLV    C  G   E++
Sbjct: 56  AVAEFFRKGREKVLVIDVACGTGFVGEEL 142
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31980772|ref|NP_038664.2| protein phosphatase 1,
catalytic subunit, gamma isoform [Mus musculus]
         (323 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

01173                                                                 582   e-167
06264                                                                 565   e-162
19040                                                                 299   1e-81
08242                                                                 273   5e-74
06084                                                                 233   1e-61
18336                                                                 171   3e-61
04295                                                                 152   2e-37
25536                                                                 149   1e-36
30980                                                                  67   7e-12
21146                                                                  64   7e-11
36367                                                                  55   5e-08
18967                                                                  54   8e-08
17953                                                                  41   8e-04
09604                                                                  27   7.5  
>01173
          Length = 2619

 Score =  582 bits (1500), Expect = e-167,   Method: Compositional matrix adjust.
 Identities = 281/302 (93%), Positives = 287/302 (95%), Gaps = 5/302 (1%)
 Frame = -1

Query: 26   KNVQLQENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPES 85
            KNVQL E+EIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPES
Sbjct: 2619 KNVQLTESEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPES 2440

Query: 86   NYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYN 145
            NYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYN
Sbjct: 2439 NYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYN 2260

Query: 146  IKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLL 205
            IKLWKTFTDCFNCLPIAAI+DEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLL
Sbjct: 2259 IKLWKTFTDCFNCLPIAAIIDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLL 2080

Query: 206  WSDPDKDVLGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVT 265
            WSDPDK+ +GWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVT
Sbjct: 2079 WSDPDKETMGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVT 1900

Query: 266  LFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPAEKKK-----PNATRPVTPPRGMITKQ 320
            LFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPA+KKK      N  RPVTPPRG    +
Sbjct: 1899 LFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKKKFPYGGLNQGRPVTPPRGNAKAK 1720

Query: 321  AK 322
             K
Sbjct: 1719 GK 1714
>06264
          Length = 999

 Score =  565 bits (1456), Expect = e-162,   Method: Compositional matrix adjust.
 Identities = 272/294 (92%), Positives = 280/294 (95%), Gaps = 5/294 (1%)
 Frame = -3

Query: 34  EIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDY 93
           EIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDY
Sbjct: 997 EIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDY 818

Query: 94  VDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFT 153
           VDRG+QSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFT
Sbjct: 817 VDRGRQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFT 638

Query: 154 DCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDV 213
           DCFNCLPIAAI+DEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDK+ 
Sbjct: 637 DCFNCLPIAAIIDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKET 458

Query: 214 LGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYC 273
           +GWGE+DRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYC
Sbjct: 457 MGWGESDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYC 278

Query: 274 GEFDNAGAMMSVDETLMCSFQILKPAEKKK-----PNATRPVTPPRGMITKQAK 322
           GEFDNAGAMMSVDETLMCSFQILKPA+KKK      +  RPVTPPRG    + K
Sbjct: 277 GEFDNAGAMMSVDETLMCSFQILKPADKKKFPYGGLSXGRPVTPPRGNAKAKGK 116
>19040
          Length = 452

 Score =  299 bits (766), Expect = 1e-81,   Method: Compositional matrix adjust.
 Identities = 141/150 (94%), Positives = 145/150 (96%)
 Frame = -3

Query: 36  RGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVD 95
           RGLCLKSREIFL QPILLELEAPL ICGDIHGQY DLLRLFEYGGFPP +NYLFLGDYVD
Sbjct: 450 RGLCLKSREIFLQQPILLELEAPLIICGDIHGQYTDLLRLFEYGGFPPAANYLFLGDYVD 271

Query: 96  RGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDC 155
           RGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYN+KLWKTFTDC
Sbjct: 270 RGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNVKLWKTFTDC 91

Query: 156 FNCLPIAAIVDEKIFCCHGGLSPDLQSMEQ 185
           FNCLP+AAI+DEKIFCCHGGLSPDLQ MEQ
Sbjct: 90  FNCLPVAAIIDEKIFCCHGGLSPDLQGMEQ 1
>08242
          Length = 3368

 Score =  273 bits (699), Expect = 5e-74,   Method: Compositional matrix adjust.
 Identities = 128/269 (47%), Positives = 189/269 (70%), Gaps = 3/269 (1%)
 Frame = -1

Query: 44   EIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLET 103
            EI + +  +  +++P+ +CGDIHGQ+YDL  LF+ GG  P++NYLF+GD+VDRG  S+ET
Sbjct: 3368 EILVEESNVQRVDSPVTVCGDIHGQFYDLKELFKVGGDVPDTNYLFMGDFVDRGFYSVET 3189

Query: 104  ICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRY-NIKLWKTFTDCFNCLPIA 162
              LLLA K++YP+   L+RGNHE   I ++YGFYDEC R+Y +I +W+  T+ F+ L ++
Sbjct: 3188 FLLLLALKVRYPDRITLIRGNHESRQITQVYGFYDECLRKYGSITVWRYCTEIFDYLSLS 3009

Query: 163  AIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVLGWGENDRG 222
            AI+D KIFC HGGLSP +Q+++QIR I R  +VP  G +CDLLWSDP+ D+ GWG + RG
Sbjct: 3008 AIIDGKIFCVHGGLSPSIQTLDQIRSIDRKQEVPHDGPMCDLLWSDPE-DMQGWGVSPRG 2832

Query: 223  VSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAM 282
              + FG++VV++F   + +DLICRAHQ+V +GY++     ++T++SAPNYC    N  A+
Sbjct: 2831 AGYLFGSDVVSQFNAANXIDLICRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAI 2652

Query: 283  MSVDETLMCSFQILK--PAEKKKPNATRP 309
            + +DE L   F I +  P E +   + +P
Sbjct: 2651 LELDEHLQRDFTIFEAAPQEARGIPSKKP 2565
>06084
          Length = 1739

 Score =  233 bits (593), Expect = 1e-61,   Method: Compositional matrix adjust.
 Identities = 121/250 (48%), Positives = 168/250 (67%), Gaps = 1/250 (0%)
 Frame = -2

Query: 66   HGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNH 125
            HGQ+YDL+ LF+ GG  P++NY+F+GD+VDRG  SLET  LLL  K K+P+   LLRGNH
Sbjct: 1738 HGQFYDLMELFKTGGEMPDTNYVFMGDFVDRGYFSLETFTLLLTLKAKWPDKIVLLRGNH 1559

Query: 126  ECASINRIYGFYDECKRRY-NIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSME 184
            E   I +IYGFYDEC+ +Y N   W+     F+ L IAAI+DE I C HGGLSPD+++++
Sbjct: 1558 ESRQITQIYGFYDECQTKYGNANAWRYCCRVFDLLTIAAIIDECILCVHGGLSPDIKTID 1379

Query: 185  QIRRIMRPTDVPDQGLLCDLLWSDPDKDVLGWGENDRGVSFTFGAEVVAKFLHKHDLDLI 244
            QIR I R  ++P +G  CDL+WSDP+ DV  W  + RG  + FGA+V A+F+  ++L LI
Sbjct: 1378 QIRTIERNQEIPHKGAFCDLVWSDPE-DVDTWAMSPRGAGWLFGAKVTAEFVASNNLKLI 1202

Query: 245  CRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPAEKKKP 304
            CRAHQ+V +GY++    +LVT++SAPNYC    N  A++S  +      ++ K      P
Sbjct: 1201 CRAHQLVHEGYKYMFDEKLVTVWSAPNYCYRCGNIAAVLSFTDAEHHEAKLFKAV----P 1034

Query: 305  NATRPVTPPR 314
            ++ R V PPR
Sbjct: 1033 DSER-VIPPR 1007
>18336
          Length = 465

 Score =  171 bits (433), Expect(3) = 3e-61,   Method: Compositional matrix adjust.
 Identities = 86/111 (77%), Positives = 89/111 (80%)
 Frame = +2

Query: 26  KNVQLQENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPES 85
           KNVQL E +       SR I L       + +   ICGDIHGQYYDLLRLFEYGGFPPES
Sbjct: 2   KNVQLSEQK*EAYV*ISRNI-LESAYSFRIRSTT*ICGDIHGQYYDLLRLFEYGGFPPES 178

Query: 86  NYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGF 136
           NYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGF
Sbjct: 179 NYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGF 331

 Score = 73.9 bits (180), Expect(3) = 3e-61,   Method: Compositional matrix adjust.
 Identities = 32/34 (94%), Positives = 33/34 (97%)
 Frame = +1

Query: 137 YDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIF 170
           YDECKRRYNIKLWKTFTDCFNCLPIAAI+D KIF
Sbjct: 331 YDECKRRYNIKLWKTFTDCFNCLPIAAIIDVKIF 432

 Score = 28.9 bits (63), Expect(3) = 3e-61,   Method: Compositional matrix adjust.
 Identities = 11/12 (91%), Positives = 11/12 (91%)
 Frame = +3

Query: 170 FCCHGGLSPDLQ 181
            CCHGGLSPDLQ
Sbjct: 429 LCCHGGLSPDLQ 464
>04295
          Length = 748

 Score =  152 bits (384), Expect = 2e-37,   Method: Compositional matrix adjust.
 Identities = 72/92 (78%), Positives = 80/92 (86%), Gaps = 6/92 (6%)
 Frame = -1

Query: 229 AEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDET 288
            +VV+KFL++HDLDLI RAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAG MMSVDET
Sbjct: 748 GDVVSKFLNRHDLDLITRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDET 569

Query: 289 LMCSFQILKPAEKKKP------NATRPVTPPR 314
           LMCSFQILKP+EKK        N+ RP+TPP+
Sbjct: 568 LMCSFQILKPSEKKAKYQYGGLNSGRPITPPK 473
>25536
          Length = 486

 Score =  149 bits (376), Expect = 1e-36,   Method: Compositional matrix adjust.
 Identities = 64/127 (50%), Positives = 94/127 (74%), Gaps = 1/127 (0%)
 Frame = +1

Query: 29  QLQENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYL 88
           QL EN+++ LC K++EI   +  + E++ P+ +CGD+HGQ++DL+ LF  GG  P++NYL
Sbjct: 106 QLSENQVKTLCEKAKEILSKESNVQEVKCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYL 285

Query: 89  FLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRY-NIK 147
           F+GDYVDRG  S+ET+ LL+A K+++ +   +LRGNHE   I ++YGFYDEC R+Y N  
Sbjct: 286 FMGDYVDRGYYSVETVSLLVALKVRFRDRITILRGNHESRQITQVYGFYDECLRKYGNAN 465

Query: 148 LWKTFTD 154
           +WK FTD
Sbjct: 466 VWKYFTD 486
>30980
          Length = 765

 Score = 67.4 bits (163), Expect = 7e-12,   Method: Compositional matrix adjust.
 Identities = 34/75 (45%), Positives = 47/75 (62%), Gaps = 1/75 (1%)
 Frame = +3

Query: 235 FLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQ 294
           F H + L LI RAHQ+V +GY +   R +VT+FSAPNYC    N  A+M +D+ L  SF 
Sbjct: 6   FNHSNGLTLISRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDALKYSFL 185

Query: 295 ILKPAEKK-KPNATR 308
              PA ++ +P+ TR
Sbjct: 186 QFDPAPRRGEPHVTR 230
>21146
          Length = 408

 Score = 64.3 bits (155), Expect = 7e-11,   Method: Compositional matrix adjust.
 Identities = 37/78 (47%), Positives = 46/78 (58%), Gaps = 3/78 (3%)
 Frame = +3

Query: 198 QGLLCDLLWSDPDKDVLGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQ-VVEDGYE 256
           QG +CDLLWSDPD D  GWG + RG  +TFG ++   F H + L LI RAHQ V+E  + 
Sbjct: 114 QGPMCDLLWSDPD-DRGGWGISPRGAGYTFGQDISETFNHSNGLTLISRAHQLVMEVMFW 290

Query: 257 FFAKRQLVTLF--SAPNY 272
           F    Q   L+  S  NY
Sbjct: 291 FVTGMQTCLLYELSLQNY 344
>36367
          Length = 827

 Score = 54.7 bits (130), Expect = 5e-08,   Method: Compositional matrix adjust.
 Identities = 39/132 (29%), Positives = 66/132 (50%), Gaps = 20/132 (15%)
 Frame = +1

Query: 173 HGGL-SPDLQS---MEQIRRIMRPTDVP--DQGLLCDLLWSDPD-------------KDV 213
           HGG+ SP+ +    +E I +I  P   P  D  +  ++LWSDP              K+ 
Sbjct: 1   HGGIPSPENEGGGHLEAINKIPVPLSDPEVDSPMAWEILWSDPISVDLVSPEVLKDMKEH 180

Query: 214 LGWGENDR-GVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNY 272
            G+  N R G +  F    +  FL ++ L  + RAH+V E G++   + +L+T+FS+  Y
Sbjct: 181 HGFTFNSRRGTAHFFSCNALLAFLERNGLSHVIRAHEVQEVGFQVQQQGKLLTVFSSSRY 360

Query: 273 CGEFDNAGAMMS 284
           CG  + A  +++
Sbjct: 361 CGGSNEAACVLA 396
>18967
          Length = 440

 Score = 53.9 bits (128), Expect = 8e-08,   Method: Compositional matrix adjust.
 Identities = 23/46 (50%), Positives = 34/46 (73%)
 Frame = +2

Query: 241 LDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVD 286
           LDLICRAHQ+V +G ++  + +LVT++SAPNYC    N  A++S +
Sbjct: 2   LDLICRAHQLVNEGIKYMFEGKLVTVWSAPNYCYRCGNVAAILSFE 139
>17953
          Length = 626

 Score = 40.8 bits (94), Expect = 8e-04,   Method: Compositional matrix adjust.
 Identities = 20/56 (35%), Positives = 32/56 (57%), Gaps = 6/56 (10%)
 Frame = -2

Query: 236 LHKHDLDLICRAHQVVEDGYEFFAKRQ------LVTLFSAPNYCGEFDNAGAMMSV 285
           L +++L  I RAH+  + GY  + K Q      L+T+FSAPNY   ++N   ++S 
Sbjct: 625 LQQNNLLSIIRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKVQLLST 458
>09604
          Length = 1098

 Score = 27.3 bits (59), Expect = 7.5,   Method: Compositional matrix adjust.
 Identities = 11/30 (36%), Positives = 18/30 (60%)
 Frame = +3

Query: 289 LMCSFQILKPAEKKKPNATRPVTPPRGMIT 318
           L+CSFQ+ K   K++  +TRP    + + T
Sbjct: 846 LLCSFQVSKNKTKRRKRSTRPFKGNQNLCT 935
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31981304|ref|NP_038505.2| ATPase, H+ transporting, V0
subunit D isoform 1 [Mus musculus]
         (351 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

01717                                                                 582   e-167
>01717
          Length = 1778

 Score =  582 bits (1500), Expect = e-167,   Method: Compositional matrix adjust.
 Identities = 268/348 (77%), Positives = 311/348 (89%)
 Frame = -3

Query: 4    FPELYFNVDNGYLEGLVRGLKAGVLSQADYLNLVQCETLEDLKLHLQSTDYGNFLANEAS 63
            FPEL FN+D+GYLEGLVRG K+G+L Q+DYLNLVQCETLEDLKLHLQSTDYGNFLANE S
Sbjct: 1731 FPELSFNIDHGYLEGLVRGFKSGILRQSDYLNLVQCETLEDLKLHLQSTDYGNFLANEPS 1552

Query: 64   PLTVSVIDDKLKEKMVVEFRHMRNHAYEPLASFLDFITYSYMIDNVILLITGTLHQRSIA 123
            PLTVSVIDDKL+EK+V+EF+H+RNH  EPLA+FLD++TY YMIDN++LLITGTLHQR I+
Sbjct: 1551 PLTVSVIDDKLREKLVIEFQHLRNHCLEPLATFLDYMTYGYMIDNIVLLITGTLHQRPIS 1372

Query: 124  ELVPKCHPLGSFEQMEAVNIAQTPAELYNAILVDTPLAAFFQDCISEQDLDEMNIEIIRN 183
            EL+ KCHPLGSFEQMEA++IA TPAELYNA+LVDTPLA +F DCI EQDLDEMNIEIIRN
Sbjct: 1371 ELISKCHPLGSFEQMEAIHIASTPAELYNAVLVDTPLAPYFIDCILEQDLDEMNIEIIRN 1192

Query: 184  TLYKAYLESFYKFCTLLGGTTADAMCPILEFEADRRAFIITINSFGTELSKEDRAKLFPH 243
            TLYKAYLE FY FC  +GG TA+ MC  L FEADRRAFIITINSFGTEL+KEDR KL+P 
Sbjct: 1191 TLYKAYLEDFYNFCKQMGGATAEVMCEALAFEADRRAFIITINSFGTELTKEDREKLYPR 1012

Query: 244  CGRLYPEGLAQLARADDYEQVKNVADYYPEYKLLFEGAGSNPGDKTLEDRFFEHEVKLNK 303
            CG LYP+GL  L++ +DY+QV+ VADYY  YK LF+ AG+NPGDKTLED+FFEHEVKL K
Sbjct: 1011 CGHLYPDGLDMLSQCEDYDQVRAVADYYAAYKELFDDAGTNPGDKTLEDKFFEHEVKLMK 832

Query: 304  LAFLNQFHFGVFYAFVKLKEQECRNIVWIAECIAQRHRAKIDNYIPIF 351
             +F++QF FGVFY++VKLKEQE RNI+WIAEC+AQRHRAKID+YIP+F
Sbjct: 831  NSFMHQFQFGVFYSYVKLKEQEIRNIIWIAECVAQRHRAKIDSYIPVF 688
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|162417975|ref|NP_034627.3| isocitrate dehydrogenase 1
(NADP+), soluble [Mus musculus]
         (414 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

01970                                                                 581   e-166
23955                                                                 126   2e-29
>01970
          Length = 2861

 Score =  581 bits (1498), Expect = e-166,   Method: Compositional matrix adjust.
 Identities = 272/397 (68%), Positives = 321/397 (80%)
 Frame = -1

Query: 10   VVEMQGDEMTRXXXXXXXXXXXXPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKYNV 69
            VVE+ GDEMTR            PY+++D   YDLG+  RD TNDQVT D+AEAIKKYNV
Sbjct: 2849 VVELDGDEMTRIIWEKIKDRLIFPYLDVDCKYYDLGLPYRDQTNDQVTIDSAEAIKKYNV 2670

Query: 70   GVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVTGWVKPII 129
            G+KCATITPDE+RVEEFKLK+MW SPNGTIRNILGGTVFRE IIC+ IPRLV GW + I+
Sbjct: 2669 GIKCATITPDEERVEEFKLKKMWLSPNGTIRNILGGTVFREPIICQTIPRLVPGWTQAIV 2490

Query: 130  IGRHAYGDQYRATDFVVPGPGKVEITYTPKDGTQKVTYMVHDFEEGGGVAMGMYNQDKSI 189
            IGRHA+GDQY+ATD V+ G G +E+ +TP+ G  +VT  V DF+ GGGV M MYN D+SI
Sbjct: 2489 IGRHAHGDQYKATDLVLEGNGTLELVFTPEGGKPQVT-KVFDFKXGGGVGMAMYNTDESI 2313

Query: 190  EDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKKYKSQFEAQKICYEHR 249
             DFAH+SFQ AL K WPLY+STKNTILK+YDGRFKDIFQEI+DK+YK +F+ Q I YEHR
Sbjct: 2312 RDFAHASFQYALMKSWPLYMSTKNTILKRYDGRFKDIFQEIFDKEYKPKFDKQGIWYEHR 2133

Query: 250  LIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLICPDGKTVEAEAAH 309
            LIDDMVAQA+KS GGF+WACKNYDGDVQSD VAQGYGSLG+MTSVL+CPDGKT+EAEAAH
Sbjct: 2132 LIDDMVAQALKSSGGFVWACKNYDGDVQSDIVAQGYGSLGLMTSVLVCPDGKTIEAEAAH 1953

Query: 310  GTVTRHYRMYQKGQETSTNPIASIFAWSRGLAHRAKLDNNTELSFFAKALEDVCIETIEA 369
            GTVTRHYR +QKG  TSTNPIASIFAW+RGL HR KLD N +L  FA+ +E  C++ +++
Sbjct: 1952 GTVTRHYREHQKGNPTSTNPIASIFAWTRGLEHRGKLDGNKDLQRFAQVMEKACVDCVDS 1773

Query: 370  GFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLK 406
            G MTKDLA CI GL NV    YLNT +F++ +GE  +
Sbjct: 1772 GKMTKDLAGCIYGLKNVTPEHYLNTMDFLEAIGEEFE 1662
>23955
          Length = 699

 Score =  126 bits (316), Expect = 2e-29,   Method: Compositional matrix adjust.
 Identities = 56/96 (58%), Positives = 71/96 (73%)
 Frame = +1

Query: 311 TVTRHYRMYQKGQETSTNPIASIFAWSRGLAHRAKLDNNTELSFFAKALEDVCIETIEAG 370
           TVTRHYR +QKG  TSTNPIASIFAW+RGL HR KLD N +L  FA+ +E  C++ +++G
Sbjct: 1   TVTRHYREHQKGNPTSTNPIASIFAWTRGLEHRGKLDGNKDLQRFAQVMEKACVDCVDSG 180

Query: 371 FMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLK 406
            MTKDLA CI GL NV    YLNT +F++ +GE  +
Sbjct: 181 KMTKDLAGCIYGLKNVTPEHYLNTMDFLEAIGEEFE 288
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31560731|ref|NP_031534.2| ATPase, H+ transporting,
lysosomal V1 subunit A [Mus musculus]
         (617 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

16215                                                                 579   e-165
37977                                                                 191   9e-49
29619                                                                 130   1e-30
00590                                                                  96   4e-20
37643                                                                  69   7e-12
04005                                                                  64   2e-10
00095                                                                  49   6e-06
>16215
          Length = 1251

 Score =  579 bits (1492), Expect = e-165,   Method: Compositional matrix adjust.
 Identities = 295/402 (73%), Positives = 325/402 (80%), Gaps = 9/402 (2%)
 Frame = -3

Query: 64   IQVYEETSGVSVGDPVLRTGKPLSVELGPGIMGAIFDGIQRPLSDISSQTQSIYIPRGVN 123
            +QVYEETSGV+VGDPVLRTGKPLSV+LGPGIMG+IFDGIQRPL  I   TQSIYIP+G+N
Sbjct: 1180 VQVYEETSGVTVGDPVLRTGKPLSVQLGPGIMGSIFDGIQRPLETICDLTQSIYIPKGIN 1001

Query: 124  VSALSRDIKWEFIPSKNLRVGSHITGGDIYGIVNENSLIKHKIMLPPRNRGSVTYIAPPG 183
              AL    +WEFIPSK++RVGSHITGGDIYG+V EN LIKH+IMLPPR RG+VTYIAPPG
Sbjct: 1000 TPALDDHKQWEFIPSKDIRVGSHITGGDIYGMVPENILIKHRIMLPPRARGTVTYIAPPG 821

Query: 184  NYDASDVVLELEFEGVKEKFSMXXXXXXXXXXXXTEKLPANHPLLTGQRVLDALFPCVQG 243
            NY  +D+VLE EF+G K ++SM            +EKL AN+PLLTGQRVLD+LFPCVQG
Sbjct: 820  NYTVNDIVLETEFDGQKSQYSMLQVWPVRQMRPVSEKLAANYPLLTGQRVLDSLFPCVQG 641

Query: 244  GTTAIPGAFGCGKTVISQSLSKYSNSDVIIYVGCGERGNEMSEVLRDFPELTMEVDGKVE 303
            GTTAIPGAFGCGKTVISQSLSKYSNSDVIIYVGCGERGNEMSEVLRDFPELTMEV+GK E
Sbjct: 640  GTTAIPGAFGCGKTVISQSLSKYSNSDVIIYVGCGERGNEMSEVLRDFPELTMEVEGKPE 461

Query: 304  SIMKRTALVANTSNMPVAAREASIYTGITLSEYFRDMGYHVSMMADSTSRWAEALREISG 363
            SIMKRTALVANTSNMPVAAREASIYTGITLSEYFRDMG +VSMMADSTSRWAEALREISG
Sbjct: 460  SIMKRTALVANTSNMPVAAREASIYTGITLSEYFRDMGLNVSMMADSTSRWAEALREISG 281

Query: 364  RLAEMPADSGYPAYLGARLASFYERAGRVKCLGNP-EREGSVSIVGAVSPPGGDFSDP-- 420
            RLAEMPADSGYPAYLGARLASFYERAGRV CLGNP  R+ SV           +   P  
Sbjct: 280  RLAEMPADSGYPAYLGARLASFYERAGRVICLGNPIARDPSVLW---------ELCLPLV 128

Query: 421  VTSATLGIVQVFWGLDKKLAQRKHF------PSVNWLISYSK 456
            VTS T    + +          + +      P++NWLISYSK
Sbjct: 127  VTSLTR*RRRRWASCRCSGVWTRSWLSVNTSPTINWLISYSK 2
>37977
          Length = 510

 Score =  191 bits (484), Expect = 9e-49,   Method: Compositional matrix adjust.
 Identities = 87/107 (81%), Positives = 100/107 (93%)
 Frame = +1

Query: 498 KASLAETDKITLEVAKLIKDDFLQQNGYTPYDRFCPFYKTVGMLSNMISFYDMARRAVET 557
           K SLAE+DKITLEVAKLIKDD+LQQNGYTPYDRFCPFYKTVGML N+I+FYDM+R AVE+
Sbjct: 4   KGSLAESDKITLEVAKLIKDDYLQQNGYTPYDRFCPFYKTVGMLRNIIAFYDMSRHAVES 183

Query: 558 TAQSDNKITWSIIREHMGEILYKLSSMKFKDPVKDGEAKIKADYAQL 604
           TAQS+NKITWSIIRE + ++LYKLSSMKFKDPVKDGE KI+AD+ +L
Sbjct: 184 TAQSENKITWSIIREQLSDVLYKLSSMKFKDPVKDGEPKIRADFDEL 324
>29619
          Length = 356

 Score =  130 bits (327), Expect = 1e-30,   Method: Composition-based stats.
 Identities = 59/78 (75%), Positives = 70/78 (89%)
 Frame = +1

Query: 540 MLSNMISFYDMARRAVETTAQSDNKITWSIIREHMGEILYKLSSMKFKDPVKDGEAKIKA 599
           ML N+I FYDMAR +VE+TAQS+NKITW++IRE MG I+Y+LSSMKFKDPVKDGEAKIKA
Sbjct: 1   MLKNIIDFYDMARHSVESTAQSENKITWNVIREAMGNIMYQLSSMKFKDPVKDGEAKIKA 180

Query: 600 DYAQLLEDMQNAFRSLED 617
           D+ QL ED+Q AFR+LED
Sbjct: 181 DFEQLHEDLQQAFRNLED 234
>00590
          Length = 2486

 Score = 95.9 bits (237), Expect = 4e-20,   Method: Compositional matrix adjust.
 Identities = 82/291 (28%), Positives = 138/291 (47%), Gaps = 5/291 (1%)
 Frame = +1

Query: 240 CVQGGTTAIPGAFGCGKTVISQSLSKYSNSDVIIYVGCGERGNEMSEVLRDFPELTMEVD 299
           C QGG   +PG     K+V    L  + ++  I++   G       E+ R F +   E +
Sbjct: 88  CRQGGLVKLPG-----KSV----LDDHDDNFAIVFAAMGVN----MEIARFFKQ-DFEEN 225

Query: 300 GKVESIMKRTALVANTSNMPVAAREASIYTGITLSEYFRDMGY----HVSMMADSTSRWA 355
           G +E++     L  N +N P   R  +    +T +EY   M Y    HV ++    S +A
Sbjct: 226 GSMENV----CLFLNLANDPTIERIITPRIALTTAEY---MAYQCEKHVLVILTDMSSYA 384

Query: 356 EALREISGRLAEMPADSGYPAYLGARLASFYERAGRVKCLGNPEREGSVSIVGAVSPPGG 415
           EALRE+S    E+P   G+P Y+   LA+ YERAGRV+      R GS++ +  ++ P  
Sbjct: 385 EALREVSAAREEVPGRRGFPGYMYTDLATIYERAGRVEG-----RNGSITQIPILTMPND 549

Query: 416 DFSDPVTSATLGIVQVFWGLDKKLAQRKHFPSVNWLISYSKYMR-ALDEYYDKHFTEFVP 474
           D + P+   T  I +    +D++L  R+ +P +N L S S+ M+ A+ E   +     V 
Sbjct: 550 DITHPIPDLTGYITEGQIYVDRQLHNRQIYPPINVLPSLSRLMKSAIGEGMTREDHSDVS 729

Query: 475 LRTKAKEILQEEEDLAEIVQLVGKASLAETDKITLEVAKLIKDDFLQQNGY 525
            +  A   +   +D+  +  +VG+ +L   D + LE     + +F+ Q  Y
Sbjct: 730 NQLYACYAIG--KDVQAMKAVVGEEALTPEDLLYLEFLTKFEKNFISQGHY 876
>37643
          Length = 1463

 Score = 68.6 bits (166), Expect = 7e-12,   Method: Compositional matrix adjust.
 Identities = 63/248 (25%), Positives = 115/248 (46%), Gaps = 15/248 (6%)
 Frame = -3

Query: 224  NHPLLTGQRVLDALFPCVQGGTTAIPGAFGCGKT------VISQSLSKYSNSD----VII 273
              P+ TG + +D+L P  +G    I G    GKT      +I+Q      N++      I
Sbjct: 1398 KEPMQTGIKAVDSLVPIGRGQRELIIGDRQTGKTAVAVDTIINQKRLNDGNNEKQKLYCI 1219

Query: 274  YVGCGERGNEMSEVLRDFPELTMEVDGKVESIMKRTALVANTSNMPVAAREASIYTGITL 333
            YV  G++ + ++++++   +            MK T +V+ T++     +  + Y+G  +
Sbjct: 1218 YVAIGQKRSTVAQLVKRLTD---------ADAMKYTIVVSATASDAAPLQYLAPYSGCAM 1066

Query: 334  SEYFRDMGYHVSMMADSTSRWAEALREISGRLAEMPADSGYPA---YLGARLASFYERAG 390
             E+FRD G H  ++ D  S+ A A R++S  L   P    YP    YL +RL    ERA 
Sbjct: 1065 GEFFRDNGMHALIIYDDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRL---LERAA 895

Query: 391  RVKCLGNPEREGSVSIVGAVSPPGGDFSDPVTSATLGIV--QVFWGLDKKLAQRKHFPSV 448
            +   + +    GS++ +  +    GD S  + +  + I   Q+F  L+ +L  +   P++
Sbjct: 894  K---MNDDNGGGSLTALPVIETQAGDVSAYIPTNVISITDGQIF--LETELFYKGIRPAI 730

Query: 449  NWLISYSK 456
            N  +S S+
Sbjct: 729  NVGLSVSR 706
>04005
          Length = 913

 Score = 63.9 bits (154), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 48/184 (26%), Positives = 90/184 (48%), Gaps = 2/184 (1%)
 Frame = +1

Query: 341 GYHVSMMADSTSRWAEALREISGRLAEMPADSGYPAYLGARLASFYERAGRVKCLGNPER 400
           G  V +  D+  R+ +A  E+S  L  +P+  GY   L   + +  ER    K       
Sbjct: 4   GQDVLLFIDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATDMGTMQERITTTK------- 162

Query: 401 EGSVSIVGAVSPPGGDFSDPVTSATLGIVQVFWGLDKKLAQRKHFPSVNWLISYSKYM-- 458
           +GS++ V A+  P  D +DP  + T   +     L + +A+   +P+V+ L S S+ +  
Sbjct: 163 KGSITSVQAIYVPADDLTDPAPATTFAHLDATTVLSRGIAELGIYPAVDPLDSTSRILDP 342

Query: 459 RALDEYYDKHFTEFVPLRTKAKEILQEEEDLAEIVQLVGKASLAETDKITLEVAKLIKDD 518
             + E++ K       +    ++ILQ+ + L +I+ ++G   L+E DK+T+  A+ ++  
Sbjct: 343 NIVGEHHYK-------IARAVQKILQDFKSLQDIIAILGMDELSEEDKLTVSRARKMQ-R 498

Query: 519 FLQQ 522
           FL Q
Sbjct: 499 FLSQ 510
>00095
          Length = 572

 Score = 48.9 bits (115), Expect = 6e-06,   Method: Compositional matrix adjust.
 Identities = 33/123 (26%), Positives = 57/123 (46%), Gaps = 1/123 (0%)
 Frame = -2

Query: 337 FRDM-GYHVSMMADSTSRWAEALREISGRLAEMPADSGYPAYLGARLASFYERAGRVKCL 395
           FRD  G  V +  D+  R+ +A  E+S  L  +P+  GY   L   + +  ER       
Sbjct: 385 FRDEEGQDVLLFIDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATDMGTMQERI------ 224

Query: 396 GNPEREGSVSIVGAVSPPGGDFSDPVTSATLGIVQVFWGLDKKLAQRKHFPSVNWLISYS 455
                +GS++ V A+  P  D +DP  + T   +     L + +A+   +P+V+ L S S
Sbjct: 223 -TTTNKGSITSVQAIYVPADDLTDPAPATTFAHLDATTVLSRGIAELGIYPAVDPLDSTS 47

Query: 456 KYM 458
           + +
Sbjct: 46  RIL 38
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|224809300|ref|NP_001029051.2| tubulin, alpha-like 3
[Mus musculus]
         (446 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

00276                                                                 572   e-164
12457                                                                 358   e-100
06360                                                                 244   5e-65
17215                                                                 227   7e-60
03702                                                                 226   1e-59
16482                                                                 195   2e-50
13181                                                                 167   9e-42
04882                                                                 159   3e-39
05902                                                                 138   5e-33
25015                                                                  95   5e-20
28905                                                                  84   1e-16
31457                                                                  83   3e-16
39157                                                                  80   2e-15
05688                                                                  32   0.36 
04396                                                                  32   0.57 
13964                                                                  30   2.7  
22696                                                                  29   4.8  
>00276
          Length = 1330

 Score =  572 bits (1475), Expect = e-164,   Method: Compositional matrix adjust.
 Identities = 264/358 (73%), Positives = 307/358 (85%)
 Frame = -3

Query: 87   VGRYHSLFHPEQLVNGKEDAANTYARGRYSVGSEVIELVLERIRKLAEQCSGLQGFLIYR 146
             G Y  L  PEQLV GKEDAAN YARG Y++G E+++LVL+RIRKLA+QC+GLQGFLI+ 
Sbjct: 1328 TGTYRQL-SPEQLVTGKEDAANNYARGHYTIGKELVDLVLDRIRKLADQCTGLQGFLIFH 1152

Query: 147  XXXXXXXXXXXXLLMERLSVEYCKKIKLEFSVYPSPRISTAVVEPYNAILTTHSTIEYSD 206
                        L MERLSV+Y KK KLEF +YP+P++STAVVEPYN+ILTTH+T+E+SD
Sbjct: 1151 SFGGGTGSGFTSLXMERLSVDYGKKSKLEFXIYPAPQVSTAVVEPYNSILTTHTTLEHSD 972

Query: 207  CAFMVDNEALYDICQHKLGIERPSYASINRLIAQVSSSITASLRFEGPLNVDLIEFQTNL 266
            CAFMVDNEA+YDIC+  L IERP+Y ++NRLI Q+ SSITASLRF+G LNVDL EFQTNL
Sbjct: 971  CAFMVDNEAIYDICRRNLDIERPTYTNLNRLIXQIVSSITASLRFDGALNVDLTEFQTNL 792

Query: 267  VPYPRIHFPITALAPIISAEKAYQEQLSVSDVTASCFEVSNQLVKCDPRLGKYMACCLLY 326
            VPYPRIHFP+   AP+ISAEKAY EQL V+++T +CFE +NQLVKCDPR GKYMACC+LY
Sbjct: 791  VPYPRIHFPLATYAPVISAEKAYHEQLXVAEITNACFEPANQLVKCDPRHGKYMACCMLY 612

Query: 327  RGDVVPKDVNEAIAAMKSRTSVQFVDWCPTGFKVGINYQPPAVVPGGDLARVQRAVCMLS 386
            RGDVVPKDVN AIA +K++ ++QFVDWCPTGFKVGINYQPP VVPGGDLA+VQRAVCMLS
Sbjct: 611  RGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLS 432

Query: 387  NTTAIVEAWARLDHKFDLMYAKKAFLHWYITEGMELGEFVEAREDLAALEKDYEEVGL 444
            NTTAI EAWARLDHKFDLMYAK+AF+HWY+ EGME GEF EAREDLAALEKDYEEVG+
Sbjct: 431  NTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVGV 258
>12457
          Length = 781

 Score =  358 bits (919), Expect(2) = e-100,   Method: Compositional matrix adjust.
 Identities = 162/239 (67%), Positives = 200/239 (83%)
 Frame = -1

Query: 74  FMDLEPTVIDGIRVGRYHSLFHPEQLVNGKEDAANTYARGRYSVGSEVIELVLERIRKLA 133
            +DLEPTV+D +R G Y  LFHPEQLV GKEDAAN YARG Y++G E+++LVL+RIRKLA
Sbjct: 718 LVDLEPTVVDEVRTGTYRQLFHPEQLVTGKEDAANNYARGHYTIGKEIVDLVLDRIRKLA 539

Query: 134 EQCSGLQGFLIYRXXXXXXXXXXXXLLMERLSVEYCKKIKLEFSVYPSPRISTAVVEPYN 193
           +QC+GLQGFLI+             LLMERLSV+Y KK KLEF++YP+P++STAVVEPYN
Sbjct: 538 DQCTGLQGFLIFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFAIYPAPQVSTAVVEPYN 359

Query: 194 AILTTHSTIEYSDCAFMVDNEALYDICQHKLGIERPSYASINRLIAQVSSSITASLRFEG 253
           +ILTTH+T+E+SDCAFMVDNEA+YDIC+  L IERP+Y ++NRLI Q+ SSITASLRF+G
Sbjct: 358 SILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLRFDG 179

Query: 254 PLNVDLIEFQTNLVPYPRIHFPITALAPIISAEKAYQEQLSVSDVTASCFEVSNQLVKC 312
            LNVDL EFQTNLVPYPRIHFP+   AP+ISAEKAY EQL+V+++T +CFE +NQ+VKC
Sbjct: 178 ALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLTVAEITNACFEPANQMVKC 2

 Score = 24.6 bits (52), Expect(2) = e-100,   Method: Compositional matrix adjust.
 Identities = 11/22 (50%), Positives = 12/22 (54%)
 Frame = -2

Query: 58  TFFHETRAGKHVPRTLFMDLEP 79
           T   ET AGKHVPR +     P
Sbjct: 765 TPLSETGAGKHVPRAVSSXXSP 700
>06360
          Length = 1896

 Score =  244 bits (623), Expect = 5e-65,   Method: Compositional matrix adjust.
 Identities = 112/185 (60%), Positives = 141/185 (76%)
 Frame = -1

Query: 1    MRECLSIHIGQAGVQIGDACWELYCLEHGIQPDGFILDHQHDNLENPKVEHMNASLDTFF 60
            MREC+S+H+GQAGVQ+G+ACWELYCLEHGIQPDG +         +  +   + S +TFF
Sbjct: 1710 MRECISVHVGQAGVQMGNACWELYCLEHGIQPDGQMP-------SDKTIGGGDDSFNTFF 1552

Query: 61   HETRAGKHVPRTLFMDLEPTVIDGIRVGRYHSLFHPEQLVNGKEDAANTYARGRYSVGSE 120
             ET AGKHVPR +F+DLEPTV+D +R G Y  LFHPEQLV GKEDAAN YARG Y++G E
Sbjct: 1551 SETGAGKHVPRAVFVDLEPTVVDEVRTGTYRQLFHPEQLVTGKEDAANNYARGHYTIGKE 1372

Query: 121  VIELVLERIRKLAEQCSGLQGFLIYRXXXXXXXXXXXXLLMERLSVEYCKKIKLEFSVYP 180
            +++LVL+RIRKLA+QC+GLQGFLI+             LLMERLSV+Y KK KLEF++YP
Sbjct: 1371 IVDLVLDRIRKLADQCTGLQGFLIFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFAIYP 1192

Query: 181  SPRIS 185
            +P++S
Sbjct: 1191 APQVS 1177
>17215
          Length = 632

 Score =  227 bits (579), Expect = 7e-60,   Method: Compositional matrix adjust.
 Identities = 102/122 (83%), Positives = 113/122 (92%)
 Frame = +3

Query: 324 LLYRGDVVPKDVNEAIAAMKSRTSVQFVDWCPTGFKVGINYQPPAVVPGGDLARVQRAVC 383
           +LYRGDVVPKDVN AIA +K++ ++QFVDWCPTGFKVGINYQPP VVPGGDLA+VQRAVC
Sbjct: 3   MLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVC 182

Query: 384 MLSNTTAIVEAWARLDHKFDLMYAKKAFLHWYITEGMELGEFVEAREDLAALEKDYEEVG 443
           MLSNTTAI EAWARLDHKFDLMYAK+AF+HWY+ EGME GEF EAREDLAALEKDYEEVG
Sbjct: 183 MLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVG 362

Query: 444 LS 445
           + 
Sbjct: 363 VD 368
>03702
          Length = 1932

 Score =  226 bits (576), Expect = 1e-59,   Method: Compositional matrix adjust.
 Identities = 108/153 (70%), Positives = 130/153 (84%)
 Frame = +1

Query: 162  ERLSVEYCKKIKLEFSVYPSPRISTAVVEPYNAILTTHSTIEYSDCAFMVDNEALYDICQ 221
            ERLSV+Y KK KLEF++YP+P++STAVVEPYN+ILTTH+T+E+SDCAFMVDNEA+YDIC+
Sbjct: 1459 ERLSVDYGKKSKLEFAIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICR 1638

Query: 222  HKLGIERPSYASINRLIAQVSSSITASLRFEGPLNVDLIEFQTNLVPYPRIHFPITALAP 281
              L IERP Y ++NRLI Q+ SSITASLRF+G LNVDL EFQTNLVP P    P   L P
Sbjct: 1639 RNLDIERPXYTNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNLVPTPH-PLPPGHLCP 1815

Query: 282  IISAEKAYQEQLSVSDVTASCFEVSNQLVKCDP 314
            +ISAEKAY EQL+V++VT +CFE +NQLVKCDP
Sbjct: 1816 VISAEKAYHEQLTVAEVTNACFEPANQLVKCDP 1914
>16482
          Length = 837

 Score =  195 bits (496), Expect = 2e-50,   Method: Compositional matrix adjust.
 Identities = 100/255 (39%), Positives = 146/255 (57%)
 Frame = +1

Query: 1   MRECLSIHIGQAGVQIGDACWELYCLEHGIQPDGFILDHQHDNLENPKVEHMNASLDTFF 60
           MRE + +  GQ G QIG   WE+   EHGI P G    H   +L+   +E +N     ++
Sbjct: 100 MREIVHMQAGQCGNQIGAKFWEVISDEHGIDPTGTY--HGDSDLQ---LERINV----YY 252

Query: 61  HETRAGKHVPRTLFMDLEPTVIDGIRVGRYHSLFHPEQLVNGKEDAANTYARGRYSVGSE 120
           +E   GK+VPR + +DLEP  +D +R G +  +F P+  V G+  A N +A+G Y+ G+E
Sbjct: 253 NEATGGKYVPRAVLVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAE 432

Query: 121 VIELVLERIRKLAEQCSGLQGFLIYRXXXXXXXXXXXXLLMERLSVEYCKKIKLEFSVYP 180
           +++ VL+ +RK AE C  LQGF +              LL+ ++  EY  +I   FSV P
Sbjct: 433 LVDSVLDVVRKEAESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVVP 612

Query: 181 SPRISTAVVEPYNAILTTHSTIEYSDCAFMVDNEALYDICQHKLGIERPSYASINRLIAQ 240
           SP++S  VVEPYNA L+ H  +E +D  + +DNEALYDIC   L +  P+Y  +N L++ 
Sbjct: 613 SPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSA 792

Query: 241 VSSSITASLRFEGPL 255
             S +T  LRF G L
Sbjct: 793 TMSGVTTCLRFPGQL 837
>13181
          Length = 1092

 Score =  167 bits (422), Expect = 9e-42,   Method: Compositional matrix adjust.
 Identities = 77/225 (34%), Positives = 124/225 (55%)
 Frame = -3

Query: 217  YDICQHKLGIERPSYASINRLIAQVSSSITASLRFEGPLNVDLIEFQTNLVPYPRIHFPI 276
            YDIC   L +  P+Y  +N L++   S +T  LRF G LN DL +   N+VP+PR+HF +
Sbjct: 1090 YDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFM 911

Query: 277  TALAPIISAEKAYQEQLSVSDVTASCFEVSNQLVKCDPRLGKYMACCLLYRGDVVPKDVN 336
               AP+ S        L+V ++T   F+  N +  CDPR G+Y+    ++RG +  K+V+
Sbjct: 910  PGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAMFRGRMSMKEVD 731

Query: 337  EAIAAMKSRTSVQFVDWCPTGFKVGINYQPPAVVPGGDLARVQRAVCMLSNTTAIVEAWA 396
            E +  ++++ S  FV+W P   K  +   PP          ++ +   + N+TAI E + 
Sbjct: 730  EQMLNVQNKNSSYFVEWIPNNVKTAVCDIPP--------RGLKMSATFVGNSTAIQELFK 575

Query: 397  RLDHKFDLMYAKKAFLHWYITEGMELGEFVEAREDLAALEKDYEE 441
            R+  +F  M+ +KAFLHWY  EGM+  EF EA  ++  L  +Y++
Sbjct: 574  RISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQ 440
>04882
          Length = 1136

 Score =  159 bits (401), Expect = 3e-39,   Method: Compositional matrix adjust.
 Identities = 73/219 (33%), Positives = 121/219 (55%)
 Frame = +2

Query: 223 KLGIERPSYASINRLIAQVSSSITASLRFEGPLNVDLIEFQTNLVPYPRIHFPITALAPI 282
           K+ +  P+Y  +N L++   S +T  LRF G LN DL +   N+VP+PR+HF +   AP+
Sbjct: 305 KI*VHTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPL 484

Query: 283 ISAEKAYQEQLSVSDVTASCFEVSNQLVKCDPRLGKYMACCLLYRGDVVPKDVNEAIAAM 342
            S        L+V ++T   F+  N +  CDPR G+Y+    ++RG +  K+V+E +  +
Sbjct: 485 TSRGSQQYRALTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNV 664

Query: 343 KSRTSVQFVDWCPTGFKVGINYQPPAVVPGGDLARVQRAVCMLSNTTAIVEAWARLDHKF 402
           +++ S  FV+W P   K  +   PP          ++ +   + N+TAI E + R+  +F
Sbjct: 665 QNKNSSYFVEWIPNNVKTAVCDIPP--------RGLKMSATFIGNSTAIQELFKRISEQF 820

Query: 403 DLMYAKKAFLHWYITEGMELGEFVEAREDLAALEKDYEE 441
             M+ +KAFLHWY  EGM+  EF EA  ++  L  +Y++
Sbjct: 821 TAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQ 937
>05902
          Length = 1127

 Score =  138 bits (347), Expect = 5e-33,   Method: Compositional matrix adjust.
 Identities = 85/289 (29%), Positives = 158/289 (54%), Gaps = 8/289 (2%)
 Frame = +2

Query: 160 LMERLSVEYCKKIKLEFSVYPS-PRISTAVVEPYNAILTTHSTIEYSDCAFMVDNEALYD 218
           L+E+L+  + KK+   +SV+P+   IS  VV+PYN++LT     + +DC  ++DN AL  
Sbjct: 65  LLEKLNDRFPKKLIQTYSVFPNVDEISDVVVQPYNSLLTLKRLTQNADCVVVLDNTALNR 244

Query: 219 ICQHKLGIERPSYASINRLIAQVSSSITASLRFEGPLNVDLIEFQTNLVPYPRIHFPITA 278
           I   +L I+ P++A +N+L++ V S+ T +LR+ G +N DLI    +L+P PR+HF +T 
Sbjct: 245 IAADRLHIDTPTFAQVNQLVSTVMSTSTTTLRYPGYMNNDLIGLIASLIPTPRLHFLMTG 424

Query: 279 LAPIIS-AEKAYQEQLSVSDVTASCFEVSNQLVKCDPRLGK---YMACCLLYRGDVVPKD 334
             P+ + ++ A   + +V DV     +  N +V           Y++   + +G+V P  
Sbjct: 425 YTPLTTDSQVANVRKTTVLDVMRRLLQPKNMMVSTPVHRQANHCYISILNIIQGEVDPTQ 604

Query: 335 VNEAIAAMKSRTSVQFVDWCPTGFKVGINYQPPAVVPGGDLARVQRAVCMLSNTTAIVEA 394
           V++++  ++ R   QF+ W P   +V ++ + P V     ++ +     ML+N T+I   
Sbjct: 605 VHKSLQRIRERKLAQFIPWGPASIQVALSRKSPYVQTAHRVSGL-----MLANHTSISHL 769

Query: 395 WARLDHKFDLMYAKKAFLHWYITEGM---ELGEFVEAREDLAALEKDYE 440
           + R+  ++D +  ++AF+  +  E +    L EF  +RE L  L  +Y+
Sbjct: 770 FERILRQYDKLRKREAFMDQFKKEAIFKDNLDEFDNSREALQLLVDEYQ 916
>25015
          Length = 458

 Score = 95.1 bits (235), Expect = 5e-20,   Method: Compositional matrix adjust.
 Identities = 47/124 (37%), Positives = 74/124 (59%)
 Frame = -3

Query: 21  WELYCLEHGIQPDGFILDHQHDNLENPKVEHMNASLDTFFHETRAGKHVPRTLFMDLEPT 80
           WE+   EHGI P G    H   +L+   +E +N     +++E   GK+VPR + +DLEP 
Sbjct: 360 WEVISDEHGIDPTGTY--HGDSDLQ---LERIN----VYYNEATGGKYVPRAVLVDLEPG 208

Query: 81  VIDGIRVGRYHSLFHPEQLVNGKEDAANTYARGRYSVGSEVIELVLERIRKLAEQCSGLQ 140
            +D +R G +  +F P+  V G+  A N +A+G Y+ G+E+++ VL+ +RK AE C  LQ
Sbjct: 207 TMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEAESCDCLQ 28

Query: 141 GFLI 144
           GF +
Sbjct: 27  GFQL 16
>28905
          Length = 425

 Score = 84.0 bits (206), Expect = 1e-16,   Method: Composition-based stats.
 Identities = 34/108 (31%), Positives = 59/108 (54%)
 Frame = -1

Query: 260 IEFQTNLVPYPRIHFPITALAPIISAEKAYQEQLSVSDVTASCFEVSNQLVKCDPRLGKY 319
           +    N+VP+PR+HF +   AP+ S        L+V ++T   F+  N +  CDPR G+Y
Sbjct: 395 VNVAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRY 216

Query: 320 MACCLLYRGDVVPKDVNEAIAAMKSRTSVQFVDWCPTGFKVGINYQPP 367
           +    ++RG +  K+V+E +  ++++ S  FV+W P   K  +   PP
Sbjct: 215 LTVAAMFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPP 72
>31457
          Length = 1530

 Score = 82.8 bits (203), Expect = 3e-16,   Method: Compositional matrix adjust.
 Identities = 39/124 (31%), Positives = 68/124 (54%)
 Frame = +3

Query: 318 KYMACCLLYRGDVVPKDVNEAIAAMKSRTSVQFVDWCPTGFKVGINYQPPAVVPGGDLAR 377
           KY+    ++RG +  K+V+E +  ++++ S  FV+W P   K  +   PP          
Sbjct: 234 KYLTVAAMFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPR--------G 389

Query: 378 VQRAVCMLSNTTAIVEAWARLDHKFDLMYAKKAFLHWYITEGMELGEFVEAREDLAALEK 437
           ++ +   + N+TAI E + R+  +F  M+ +KAFLHWY  EGM+  EF EA  ++  L  
Sbjct: 390 LKMSSTFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS 569

Query: 438 DYEE 441
           +Y++
Sbjct: 570 EYQQ 581
>39157
          Length = 488

 Score = 79.7 bits (195), Expect = 2e-15,   Method: Compositional matrix adjust.
 Identities = 46/134 (34%), Positives = 72/134 (53%), Gaps = 3/134 (2%)
 Frame = -1

Query: 1   MRECLSIHIGQAGVQIGDACWELYCLEHGIQPDGFILDHQHDNLENPKVEHMNASLDTFF 60
           MRE + +  GQ G QIG   WE+   EHGI P G    H   +L+   +E +N     ++
Sbjct: 443 MREIVHLQAGQCGNQIGAKFWEVISDEHGIDPTGTY--HGDSDLQ---LERINV----YY 291

Query: 61  HETRAGKHVPRTLFMDLEPTVIDGIRVGRYHS--LFHPEQLVNGKEDAANTYA-RGRYSV 117
           +E   GK+VPR + +DLEP  +D +R G      +F P+  V G+  A N +  +     
Sbjct: 290 NEATGGKYVPRAVLVDLEPGTMDSVRSGSPFGPKIFRPDNFVFGQSGAGNNWGQKDTTQR 111

Query: 118 GSEVIELVLERIRK 131
           G+E+++ VL+ +RK
Sbjct: 110 GAELVDSVLDVVRK 69
>05688
          Length = 1160

 Score = 32.3 bits (72), Expect = 0.36,   Method: Compositional matrix adjust.
 Identities = 14/40 (35%), Positives = 22/40 (55%)
 Frame = +1

Query: 246  TASLRFEGPLNVDLIEFQTNLVPYPRIHFPITALAPIISA 285
            T S   E PLN++L  ++ +    P IH P+T + P+  A
Sbjct: 1021 TGSCYCETPLNINLTAYRQSRWTLPVIHMPVTWIQPVTQA 1140
>04396
          Length = 1170

 Score = 32.0 bits (71), Expect = 0.57,   Method: Compositional matrix adjust.
 Identities = 27/100 (27%), Positives = 40/100 (40%), Gaps = 6/100 (6%)
 Frame = -2

Query: 259  LIEFQTNLVPYPRIHFPITALAPIISAEKAYQEQLSVSDVTASCFEVSNQLVKCDPRLGK 318
            L  F +NL P  +    ITAL       KAY + +  S      +E S  ++   P +  
Sbjct: 1145 LNNFPSNLHPMSQFSAAITALNSESKFAKAYADGVHKSKYWELVYEDSMDMIAKLPTVAS 966

Query: 319  YMACCLLYRGDVVP------KDVNEAIAAMKSRTSVQFVD 352
             + C  LYR  V P      KD +E   +M      +F +
Sbjct: 965  IIYCN-LYRDGVTPCAIDTNKDWSENFTSMLGYKDAEFTE 849
>13964
          Length = 528

 Score = 29.6 bits (65), Expect = 2.7,   Method: Compositional matrix adjust.
 Identities = 13/14 (92%), Positives = 14/14 (100%)
 Frame = +2

Query: 431 DLAALEKDYEEVGL 444
           DLAALEKDYEEVG+
Sbjct: 230 DLAALEKDYEEVGV 271
>22696
          Length = 1194

 Score = 28.9 bits (63), Expect = 4.8,   Method: Compositional matrix adjust.
 Identities = 14/40 (35%), Positives = 19/40 (47%), Gaps = 7/40 (17%)
 Frame = +1

Query: 9   IGQAGVQIGDACWELY-------CLEHGIQPDGFILDHQH 41
           + +  V + D C  LY       CL+ G+  D F LDH H
Sbjct: 364 MNENNVVLHDICKYLYFVLLNYNCLQDGVNEDSFFLDHIH 483
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|34328206|ref|NP_035840.2| tryptophanyl-tRNA
synthetase [Mus musculus]
         (481 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

05814                                                                 573   e-164
08695                                                                  44   1e-04
>05814
          Length = 1242

 Score =  573 bits (1478), Expect = e-164,   Method: Compositional matrix adjust.
 Identities = 270/387 (69%), Positives = 323/387 (83%)
 Frame = +3

Query: 88  FVDPWTVRTSSAKGIDYDKLIVQFGSSKIDKELINRIERATGQRPHRFLRRGIFFSHRDM 147
           +  P   ++SS KG+DYDKLIV+FGSSKID  LI R+E+ TG+  H F+RRGIFFSHRDM
Sbjct: 33  YCKPLGXQSSSDKGVDYDKLIVRFGSSKIDDALIQRMEKVTGKPVHHFIRRGIFFSHRDM 212

Query: 148 NQILDAYENKKPFYLYTGRGPSSEAMHLGHLVPFIFTKWLQDVFNVPLVIQMSDDEKYLW 207
           + +LD YE K+PFYLYTGRGPSS+AMHLGHLVPFI TKWLQDVF+VPLVIQ++DDEKYLW
Sbjct: 213 HALLDLYEKKQPFYLYTGRGPSSDAMHLGHLVPFIMTKWLQDVFDVPLVIQLTDDEKYLW 392

Query: 208 KDLTLEQAYSYTVENAKDIIACGFDINKTFIFSDLEYMGQSPGFYRNVVKIQKHVTFNQV 267
           KDL+ ++A++ + +NAKDIIACGFD +KTFIFSD +YMG    FY+ + +IQ+ VT NQ 
Sbjct: 393 KDLSEDEAHALSYQNAKDIIACGFDEDKTFIFSDFDYMGGM--FYKTICRIQRRVTNNQA 566

Query: 268 KGIFGFTDSDCIGKISFPAVQAAPSFSNSFPKIFRDRTDIQCLIPCAIDQDPYFRMTRDV 327
            GIFGFT    IGK SFPA+QAAPSFS+SFP IF  + ++ CLIPCAIDQDPYFRMTRDV
Sbjct: 567 WGIFGFTGESNIGKNSFPAIQAAPSFSSSFPDIFNCKXNVPCLIPCAIDQDPYFRMTRDV 746

Query: 328 APRIGHPKPALLHSTFFPALQGAQTKMSASDPNSSIFLTDTAKQIKSKVNKHAFSGGRDT 387
           APR+G+PKPAL+HS FFPALQG +TKMSAS+P SSIFLTD  KQIK K+NK+AFSGGRDT
Sbjct: 747 APRLGYPKPALMHSKFFPALQGPKTKMSASEPASSIFLTDKPKQIKDKINKYAFSGGRDT 926

Query: 388 VEEHRQFGGNCEVDVSFMYLTFFLEDDDRLEQIRKDYTSGAMLTGELKKTLIDVLQPLIA 447
            EEHR++GGNCEVDVSF YL FFL+DD++LE+IR+DYTSG +LTG LKK LI VLQ LI 
Sbjct: 927 AEEHRKYGGNCEVDVSFQYLRFFLDDDEKLEKIRQDYTSGELLTGFLKKELITVLQKLIG 1106

Query: 448 EHQARRKAVTEETVKEFMTPRQLSFHF 474
           EHQ RR  VT+E VK +MTPR+L + F
Sbjct: 1107EHQERRAKVTDEMVKRYMTPRKLKYDF 1187
>08695
          Length = 861

 Score = 43.9 bits (102), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 23/52 (44%), Positives = 30/52 (57%)
 Frame = +1

Query: 14  LELFNSIATQGELVRSLKAGNAPKDEIDSAVKMLLSLKVSYKAAMGEEYKAG 65
           L L   +  QG+ VR LK G A K+E+D+AVK LL LK  +K   G +   G
Sbjct: 265 LALKAEVDAQGDKVRQLKTGGAAKEEVDAAVKKLLELKGKFKDLTGTDVAGG 420

 Score = 38.9 bits (89), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 24/57 (42%), Positives = 32/57 (56%), Gaps = 10/57 (17%)
 Frame = +1

Query: 38  DEIDSAVKMLLSLKVSYKAAMGEEY---KAGCPPGN-------PTAGRNCDSDATKA 84
           +EID+AVK+LLSLK  YK A G+++   KAG  P         P  G N   D+ +A
Sbjct: 94  EEIDAAVKVLLSLKKQYKEATGKDWTPPKAGSSPAKTAQPAAMPAVGGNAAVDSPEA 264
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|161484668|ref|NP_766295.2| protein phosphatase 1,
catalytic subunit, beta isoform [Mus musculus]
         (327 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

01173                                                                 571   e-163
06264                                                                 555   e-159
19040                                                                 300   6e-82
08242                                                                 274   4e-74
06084                                                                 225   2e-59
18336                                                                 164   2e-58
04295                                                                 188   2e-48
25536                                                                 144   6e-35
21146                                                                  61   6e-10
30980                                                                  59   2e-09
36367                                                                  57   7e-09
18967                                                                  53   2e-07
17953                                                                  41   8e-04
01222                                                                  28   6.0  
05700                                                                  27   9.0  
>01173
          Length = 2619

 Score =  571 bits (1471), Expect = e-163,   Method: Compositional matrix adjust.
 Identities = 271/295 (91%), Positives = 286/295 (96%)
 Frame = -1

Query: 25   KIVQMTEAEVRGLCIKSREIFLSQPILLELEAPLKICGDIHGQYTDLLRLFEYGGFPPEA 84
            K VQ+TE+E+RGLC+KSREIFLSQPILLELEAPLKICGDIHGQY DLLRLFEYGGFPPE+
Sbjct: 2619 KNVQLTESEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPES 2440

Query: 85   NYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRFN 144
            NYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRR+N
Sbjct: 2439 NYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYN 2260

Query: 145  IKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDTGLLCDLL 204
            IKLWKTFTDCFNCLPIAAI+DEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPD GLLCDLL
Sbjct: 2259 IKLWKTFTDCFNCLPIAAIIDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLL 2080

Query: 205  WSDPDKDVQGWGENDRGVSFTFGADVVSKFLNRHDLDLICRAHQVVEDGYEFFAKRQLVT 264
            WSDPDK+  GWGENDRGVSFTFGA+VV+KFL++HDLDLICRAHQVVEDGYEFFAKRQLVT
Sbjct: 2079 WSDPDKETMGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVT 1900

Query: 265  LFSAPNYCGEFDNAGGMMSVDETLMCSFQILKPSEKKAKYQYGGLNSGRPVTPPR 319
            LFSAPNYCGEFDNAG MMSVDETLMCSFQILKP++KK K+ YGGLN GRPVTPPR
Sbjct: 1899 LFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKK-KFPYGGLNQGRPVTPPR 1738
>06264
          Length = 999

 Score =  555 bits (1431), Expect = e-159,   Method: Compositional matrix adjust.
 Identities = 264/295 (89%), Positives = 281/295 (95%)
 Frame = -3

Query: 33  EVRGLCIKSREIFLSQPILLELEAPLKICGDIHGQYTDLLRLFEYGGFPPEANYLFLGDY 92
           E+RGLC+KSREIFLSQPILLELEAPLKICGDIHGQY DLLRLFEYGGFPPE+NYLFLGDY
Sbjct: 997 EIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDY 818

Query: 93  VDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRFNIKLWKTFT 152
           VDRG+QSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRR+NIKLWKTFT
Sbjct: 817 VDRGRQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFT 638

Query: 153 DCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDTGLLCDLLWSDPDKDV 212
           DCFNCLPIAAI+DEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPD GLLCDLLWSDPDK+ 
Sbjct: 637 DCFNCLPIAAIIDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKET 458

Query: 213 QGWGENDRGVSFTFGADVVSKFLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYC 272
            GWGE+DRGVSFTFGA+VV+KFL++HDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYC
Sbjct: 457 MGWGESDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYC 278

Query: 273 GEFDNAGGMMSVDETLMCSFQILKPSEKKAKYQYGGLNSGRPVTPPRTANPPKKR 327
           GEFDNAG MMSVDETLMCSFQILKP++KK K+ YGGL+ GRPVTPPR     K +
Sbjct: 277 GEFDNAGAMMSVDETLMCSFQILKPADKK-KFPYGGLSXGRPVTPPRGNAKAKGK 116
>19040
          Length = 452

 Score =  300 bits (768), Expect = 6e-82,   Method: Compositional matrix adjust.
 Identities = 141/150 (94%), Positives = 146/150 (97%)
 Frame = -3

Query: 35  RGLCIKSREIFLSQPILLELEAPLKICGDIHGQYTDLLRLFEYGGFPPEANYLFLGDYVD 94
           RGLC+KSREIFL QPILLELEAPL ICGDIHGQYTDLLRLFEYGGFPP ANYLFLGDYVD
Sbjct: 450 RGLCLKSREIFLQQPILLELEAPLIICGDIHGQYTDLLRLFEYGGFPPAANYLFLGDYVD 271

Query: 95  RGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRFNIKLWKTFTDC 154
           RGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRR+N+KLWKTFTDC
Sbjct: 270 RGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNVKLWKTFTDC 91

Query: 155 FNCLPIAAIVDEKIFCCHGGLSPDLQSMEQ 184
           FNCLP+AAI+DEKIFCCHGGLSPDLQ MEQ
Sbjct: 90  FNCLPVAAIIDEKIFCCHGGLSPDLQGMEQ 1
>08242
          Length = 3368

 Score =  274 bits (700), Expect = 4e-74,   Method: Compositional matrix adjust.
 Identities = 129/273 (47%), Positives = 191/273 (69%), Gaps = 1/273 (0%)
 Frame = -1

Query: 43   EIFLSQPILLELEAPLKICGDIHGQYTDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLET 102
            EI + +  +  +++P+ +CGDIHGQ+ DL  LF+ GG  P+ NYLF+GD+VDRG  S+ET
Sbjct: 3368 EILVEESNVQRVDSPVTVCGDIHGQFYDLKELFKVGGDVPDTNYLFMGDFVDRGFYSVET 3189

Query: 103  ICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRF-NIKLWKTFTDCFNCLPIA 161
              LLLA K++YP+   L+RGNHE   I ++YGFYDEC R++ +I +W+  T+ F+ L ++
Sbjct: 3188 FLLLLALKVRYPDRITLIRGNHESRQITQVYGFYDECLRKYGSITVWRYCTEIFDYLSLS 3009

Query: 162  AIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDTGLLCDLLWSDPDKDVQGWGENDRG 221
            AI+D KIFC HGGLSP +Q+++QIR I R  +VP  G +CDLLWSDP+ D+QGWG + RG
Sbjct: 3008 AIIDGKIFCVHGGLSPSIQTLDQIRSIDRKQEVPHDGPMCDLLWSDPE-DMQGWGVSPRG 2832

Query: 222  VSFTFGADVVSKFLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGM 281
              + FG+DVVS+F   + +DLICRAHQ+V +GY++     ++T++SAPNYC    N   +
Sbjct: 2831 AGYLFGSDVVSQFNAANXIDLICRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAI 2652

Query: 282  MSVDETLMCSFQILKPSEKKAKYQYGGLNSGRP 314
            + +DE L   F I + + ++A+    G+ S +P
Sbjct: 2651 LELDEHLQRDFTIFEAAPQEAR----GIPSKKP 2565
>06084
          Length = 1739

 Score =  225 bits (574), Expect = 2e-59,   Method: Compositional matrix adjust.
 Identities = 117/260 (45%), Positives = 162/260 (62%), Gaps = 1/260 (0%)
 Frame = -2

Query: 65   HGQYTDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNH 124
            HGQ+ DL+ LF+ GG  P+ NY+F+GD+VDRG  SLET  LLL  K K+P+   LLRGNH
Sbjct: 1738 HGQFYDLMELFKTGGEMPDTNYVFMGDFVDRGYFSLETFTLLLTLKAKWPDKIVLLRGNH 1559

Query: 125  ECASINRIYGFYDECKRRF-NIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSME 183
            E   I +IYGFYDEC+ ++ N   W+     F+ L IAAI+DE I C HGGLSPD+++++
Sbjct: 1558 ESRQITQIYGFYDECQTKYGNANAWRYCCRVFDLLTIAAIIDECILCVHGGLSPDIKTID 1379

Query: 184  QIRRIMRPTDVPDTGLLCDLLWSDPDKDVQGWGENDRGVSFTFGADVVSKFLNRHDLDLI 243
            QIR I R  ++P  G  CDL+WSDP+ DV  W  + RG  + FGA V ++F+  ++L LI
Sbjct: 1378 QIRTIERNQEIPHKGAFCDLVWSDPE-DVDTWAMSPRGAGWLFGAKVTAEFVASNNLKLI 1202

Query: 244  CRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDETLMCSFQILKPSEKKAK 303
            CRAHQ+V +GY++    +LVT++SAPNYC    N   ++S  +           +E    
Sbjct: 1201 CRAHQLVHEGYKYMFDEKLVTVWSAPNYCYRCGNIAAVLSFTD-----------AEHHEA 1055

Query: 304  YQYGGLNSGRPVTPPRTANP 323
              +  +     V PPRT  P
Sbjct: 1054 KLFKAVPDSERVIPPRTQTP 995
>18336
          Length = 465

 Score =  164 bits (414), Expect(3) = 2e-58,   Method: Compositional matrix adjust.
 Identities = 82/111 (73%), Positives = 88/111 (79%)
 Frame = +2

Query: 25  KIVQMTEAEVRGLCIKSREIFLSQPILLELEAPLKICGDIHGQYTDLLRLFEYGGFPPEA 84
           K VQ++E +       SR I L       + +   ICGDIHGQY DLLRLFEYGGFPPE+
Sbjct: 2   KNVQLSEQK*EAYV*ISRNI-LESAYSFRIRSTT*ICGDIHGQYYDLLRLFEYGGFPPES 178

Query: 85  NYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGF 135
           NYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGF
Sbjct: 179 NYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGF 331

 Score = 72.8 bits (177), Expect(3) = 2e-58,   Method: Compositional matrix adjust.
 Identities = 31/34 (91%), Positives = 33/34 (97%)
 Frame = +1

Query: 136 YDECKRRFNIKLWKTFTDCFNCLPIAAIVDEKIF 169
           YDECKRR+NIKLWKTFTDCFNCLPIAAI+D KIF
Sbjct: 331 YDECKRRYNIKLWKTFTDCFNCLPIAAIIDVKIF 432

 Score = 28.9 bits (63), Expect(3) = 2e-58,   Method: Compositional matrix adjust.
 Identities = 11/12 (91%), Positives = 11/12 (91%)
 Frame = +3

Query: 169 FCCHGGLSPDLQ 180
            CCHGGLSPDLQ
Sbjct: 429 LCCHGGLSPDLQ 464
>04295
          Length = 748

 Score =  188 bits (478), Expect = 2e-48,   Method: Compositional matrix adjust.
 Identities = 88/92 (95%), Positives = 90/92 (97%)
 Frame = -1

Query: 228 ADVVSKFLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDET 287
            DVVSKFLNRHDLDLI RAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDET
Sbjct: 748 GDVVSKFLNRHDLDLITRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDET 569

Query: 288 LMCSFQILKPSEKKAKYQYGGLNSGRPVTPPR 319
           LMCSFQILKPSEKKAKYQYGGLNSGRP+TPP+
Sbjct: 568 LMCSFQILKPSEKKAKYQYGGLNSGRPITPPK 473
>25536
          Length = 486

 Score =  144 bits (362), Expect = 6e-35,   Method: Compositional matrix adjust.
 Identities = 62/127 (48%), Positives = 92/127 (72%), Gaps = 1/127 (0%)
 Frame = +1

Query: 28  QMTEAEVRGLCIKSREIFLSQPILLELEAPLKICGDIHGQYTDLLRLFEYGGFPPEANYL 87
           Q++E +V+ LC K++EI   +  + E++ P+ +CGD+HGQ+ DL+ LF  GG  P+ NYL
Sbjct: 106 QLSENQVKTLCEKAKEILSKESNVQEVKCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYL 285

Query: 88  FLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRF-NIK 146
           F+GDYVDRG  S+ET+ LL+A K+++ +   +LRGNHE   I ++YGFYDEC R++ N  
Sbjct: 286 FMGDYVDRGYYSVETVSLLVALKVRFRDRITILRGNHESRQITQVYGFYDECLRKYGNAN 465

Query: 147 LWKTFTD 153
           +WK FTD
Sbjct: 466 VWKYFTD 486
>21146
          Length = 408

 Score = 60.8 bits (146), Expect = 6e-10,   Method: Compositional matrix adjust.
 Identities = 36/77 (46%), Positives = 45/77 (58%), Gaps = 3/77 (3%)
 Frame = +3

Query: 198 GLLCDLLWSDPDKDVQGWGENDRGVSFTFGADVVSKFLNRHDLDLICRAHQ-VVEDGYEF 256
           G +CDLLWSDPD D  GWG + RG  +TFG D+   F + + L LI RAHQ V+E  + F
Sbjct: 117 GPMCDLLWSDPD-DRGGWGISPRGAGYTFGQDISETFNHSNGLTLISRAHQLVMEVMFWF 293

Query: 257 FAKRQLVTLF--SAPNY 271
               Q   L+  S  NY
Sbjct: 294 VTGMQTCLLYELSLQNY 344
>30980
          Length = 765

 Score = 59.3 bits (142), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 28/70 (40%), Positives = 42/70 (60%)
 Frame = +3

Query: 234 FLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDETLMCSFQ 293
           F + + L LI RAHQ+V +GY +   R +VT+FSAPNYC    N   +M +D+ L  SF 
Sbjct: 6   FNHSNGLTLISRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDALKYSFL 185

Query: 294 ILKPSEKKAK 303
              P+ ++ +
Sbjct: 186 QFDPAPRRGE 215
>36367
          Length = 827

 Score = 57.4 bits (137), Expect = 7e-09,   Method: Compositional matrix adjust.
 Identities = 40/132 (30%), Positives = 68/132 (51%), Gaps = 20/132 (15%)
 Frame = +1

Query: 172 HGGL-SPDLQS---MEQIRRIMRPTDVP--DTGLLCDLLWSDPD-------------KDV 212
           HGG+ SP+ +    +E I +I  P   P  D+ +  ++LWSDP              K+ 
Sbjct: 1   HGGIPSPENEGGGHLEAINKIPVPLSDPEVDSPMAWEILWSDPISVDLVSPEVLKDMKEH 180

Query: 213 QGWGENDR-GVSFTFGADVVSKFLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNY 271
            G+  N R G +  F  + +  FL R+ L  + RAH+V E G++   + +L+T+FS+  Y
Sbjct: 181 HGFTFNSRRGTAHFFSCNALLAFLERNGLSHVIRAHEVQEVGFQVQQQGKLLTVFSSSRY 360

Query: 272 CGEFDNAGGMMS 283
           CG  + A  +++
Sbjct: 361 CGGSNEAACVLA 396
>18967
          Length = 440

 Score = 52.8 bits (125), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 22/46 (47%), Positives = 33/46 (71%)
 Frame = +2

Query: 240 LDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVD 285
           LDLICRAHQ+V +G ++  + +LVT++SAPNYC    N   ++S +
Sbjct: 2   LDLICRAHQLVNEGIKYMFEGKLVTVWSAPNYCYRCGNVAAILSFE 139
>17953
          Length = 626

 Score = 40.8 bits (94), Expect = 8e-04,   Method: Compositional matrix adjust.
 Identities = 20/56 (35%), Positives = 32/56 (57%), Gaps = 6/56 (10%)
 Frame = -2

Query: 235 LNRHDLDLICRAHQVVEDGYEFFAKRQ------LVTLFSAPNYCGEFDNAGGMMSV 284
           L +++L  I RAH+  + GY  + K Q      L+T+FSAPNY   ++N   ++S 
Sbjct: 625 LQQNNLLSIIRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKVQLLST 458
>01222
          Length = 744

 Score = 27.7 bits (60), Expect = 6.0,   Method: Compositional matrix adjust.
 Identities = 16/55 (29%), Positives = 27/55 (49%), Gaps = 1/55 (1%)
 Frame = -2

Query: 118 FLLRGNHECASINRIYGFYDECKRRFNIKLWKTFTDCFNCLP-IAAIVDEKIFCC 171
           F +  NH C S  ++Y   +    + NIKLW      + C+  +   V+E++F C
Sbjct: 707 FTIHSNHICRSRRKLYTEINPQHVKINIKLWHPTQFFYLCIMYVCRRVNEQVFVC 543
>05700
          Length = 913

 Score = 27.3 bits (59), Expect = 9.0,   Method: Compositional matrix adjust.
 Identities = 14/35 (40%), Positives = 19/35 (54%)
 Frame = +2

Query: 52  LELEAPLKICGDIHGQYTDLLRLFEYGGFPPEANY 86
           L L + + IC  IH  Y+DL+  F+   FPP   Y
Sbjct: 719 LALSSCISIC--IHHNYSDLVLCFQCFSFPPYL*Y 817
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|34419622|ref|NP_570951.2| poly(A) binding protein,
cytoplasmic 4 isoform 1 [Mus musculus]
         (660 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

17775                                                                 570   e-163
39438                                                                 134   8e-32
25691                                                                  74   2e-13
17681                                                                  74   2e-13
20488                                                                  67   2e-11
03744                                                                  67   2e-11
28652                                                                  66   3e-11
11687                                                                  62   5e-10
08958                                                                  60   2e-09
16427                                                                  59   9e-09
30672                                                                  57   3e-08
14258                                                                  56   5e-08
14637                                                                  56   6e-08
02343                                                                  55   7e-08
13457                                                                  45   2e-07
13822                                                                  54   3e-07
31310                                                                  52   5e-07
01278                                                                  52   7e-07
02502                                                                  50   2e-06
02140                                                                  50   4e-06
28455                                                                  49   9e-06
19868                                                                  48   2e-05
15371                                                                  47   2e-05
03000                                                                  47   2e-05
02064                                                                  47   3e-05
00029                                                                  46   4e-05
00302                                                                  45   1e-04
03903                                                                  44   2e-04
28605                                                                  43   4e-04
09736                                                                  42   7e-04
03200                                                                  42   8e-04
02091                                                                  42   0.001
00556                                                                  41   0.001
20169                                                                  41   0.002
12506                                                                  41   0.002
33516                                                                  40   0.002
02809                                                                  40   0.004
03059                                                                  39   0.004
10194                                                                  39   0.008
32386                                                                  38   0.010
03406                                                                  38   0.014
26197                                                                  38   0.014
31618                                                                  37   0.018
02347                                                                  37   0.023
05987                                                                  36   0.038
01065                                                                  36   0.045
00738                                                                  35   0.064
32733                                                                  35   0.079
15503                                                                  35   0.094
08670                                                                  35   0.12 
00781                                                                  34   0.15 
23322                                                                  34   0.20 
25950                                                                  34   0.22 
29364                                                                  34   0.24 
04988                                                                  34   0.24 
11019                                                                  34   0.24 
12350                                                                  33   0.25 
23720                                                                  33   0.27 
11126                                                                  33   0.31 
31265                                                                  33   0.34 
03097                                                                  32   0.66 
39789                                                                  32   0.71 
19980                                                                  32   0.98 
11579                                                                  32   1.1  
25632                                                                  31   1.3  
28372                                                                  31   1.4  
19733                                                                  31   1.7  
29083                                                                  30   3.0  
00741                                                                  30   3.0  
30934                                                                  30   3.1  
35379                                                                  30   3.6  
12096                                                                  30   3.8  
33791                                                                  29   4.7  
23250                                                                  29   5.7  
01937                                                                  29   6.8  
19556                                                                  29   6.8  
12593                                                                  29   7.8  
>17775
          Length = 1282

 Score =  570 bits (1468), Expect = e-163,   Method: Compositional matrix adjust.
 Identities = 283/407 (69%), Positives = 326/407 (80%), Gaps = 1/407 (0%)
 Frame = -2

Query: 1    MNAAASSYPMASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQ 60
            MN    SYPMASLYVGDLH DVTEAML+EKFS AGPVLSIRVCRDMITRRSLGYAYVNFQ
Sbjct: 1224 MNNPGPSYPMASLYVGDLHPDVTEAMLFEKFSTAGPVLSIRVCRDMITRRSLGYAYVNFQ 1045

Query: 61   QPADAERALDTMNFDVMKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFS 120
            QPADAERALDTMNFD +KG+PIRIMWSQRDPS+RKSGVGNVFIKNLDK+IDNKALYDTFS
Sbjct: 1044 QPADAERALDTMNFDTVKGRPIRIMWSQRDPSVRKSGVGNVFIKNLDKTIDNKALYDTFS 865

Query: 121  AFGNILSCKVVCDENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKERE 180
            AFGNILSCK+ CDE GSKGY FVHFET+EAA +AI+K+NGMLLN +KV+VGRF  RKER 
Sbjct: 864  AFGNILSCKIACDEQGSKGYGFVHFETEEAARQAIDKVNGMLLNGKKVYVGRFIPRKERI 685

Query: 181  AELGAKAKEFTNVYIKNFGEEVDDGNLKELFSQFGKT-LSVKVMRDXXXXXXXXXXVSYE 239
              +G K K F NVY+KNF           L  Q  +  L     R           VS+E
Sbjct: 684  MMMGDKLKRFNNVYVKNFC*GTG*RPAA*LVWQARQDHLXXGACRGEDGKSRGFGFVSFE 505

Query: 240  KHEDANKAVEEMNGKEMSGKAIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIK 299
            + E A KAV+E+NG E+SG+ I+ GRAQK+ ERQAELK +FE++K ERI+RYQGVNLY+K
Sbjct: 504  EPEGAEKAVDEINGTEVSGRIIYCGRAQKRAERQAELKERFEKIKLERINRYQGVNLYVK 325

Query: 300  NLDDTIDDEKLRREFSPFGSITSAKVMLEDGRSKGFGFVCFSSPEEATKAVTEMNGRIVG 359
            NLDD+IDDE+LR+EFS FG+ITSAK+M E GRSKGFGFVCFSSPEEATKAVTEMNGRI+ 
Sbjct: 324  NLDDSIDDERLRKEFSNFGTITSAKIMTEGGRSKGFGFVCFSSPEEATKAVTEMNGRIIV 145

Query: 360  SKPLYVALAQRKEERKAHLTNQYMQRVAGMRALPASAILNQFQPAAG 406
            +KPLYVALAQRKE+R+A L ++YMQ +A +R   ++     FQ A G
Sbjct: 144  AKPLYVALAQRKEDRRAQLASRYMQHMANLRQQQSAQFSQMFQAAPG 4
>39438
          Length = 2557

 Score =  134 bits (338), Expect = 8e-32,   Method: Compositional matrix adjust.
 Identities = 67/78 (85%), Positives = 73/78 (93%)
 Frame = +2

Query: 562 VHVQGQEPLTASMLAAAPPQEQKQMLGERLFPLIQTMHSNLAGKITGMLLEIDNSELLHM 621
           V + GQEPLTASMLAAAPPQEQKQMLGERLFPLIQ M+ +LAGKITGMLLEIDNSELLHM
Sbjct: 191 VVIPGQEPLTASMLAAAPPQEQKQMLGERLFPLIQRMYPDLAGKITGMLLEIDNSELLHM 370

Query: 622 LESPESLRSKVDEAVAVL 639
           LES ESL++KV+EAVAVL
Sbjct: 371 LESQESLKAKVEEAVAVL 424
>25691
          Length = 768

 Score = 73.9 bits (180), Expect = 2e-13,   Method: Compositional matrix adjust.
 Identities = 39/126 (30%), Positives = 76/126 (60%), Gaps = 2/126 (1%)
 Frame = -2

Query: 39  SIRVCRDMITRRSLGYAYVNFQQPADAERALDTMNFDVMKGKPIRIMWSQRDPSLRKSGV 98
           + ++ RD  T +SLGY +VN+++  DA++A+ T+N   ++ K I++  ++  PS      
Sbjct: 434 TCKLIRDKPTGQSLGYGFVNYKRQEDADKAIHTLNGLRLQNKTIKVSLAR--PSCESIKG 261

Query: 99  GNVFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENG--SKGYAFVHFETQEAADKAIE 156
            N++I  L KS+    L + F+  GNI++ +++ D+    SKG  F+ F+ +  A++AI+
Sbjct: 260 ANLYISGLPKSLTQLDLENLFTDCGNIITSRILYDQTTGLSKGVGFIRFDQRIEAERAIQ 81

Query: 157 KMNGML 162
           K+N  +
Sbjct: 80  KLNNHI 63

 Score = 58.9 bits (141), Expect = 5e-09,   Method: Compositional matrix adjust.
 Identities = 36/124 (29%), Positives = 60/124 (48%), Gaps = 2/124 (1%)
 Frame = -2

Query: 236 VSYEKHEDANKAVEEMNGKEMSGKAIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVN 295
           V+Y++ EDA+KA+  +NG  +  K I V  A+   E                    +G N
Sbjct: 380 VNYKRQEDADKAIHTLNGLRLQNKTIKVSLARPSCE------------------SIKGAN 255

Query: 296 LYIKNLDDTIDDEKLRREFSPFGSITSAKVMLED--GRSKGFGFVCFSSPEEATKAVTEM 353
           LYI  L  ++    L   F+  G+I +++++ +   G SKG GF+ F    EA +A+ ++
Sbjct: 254 LYISGLPKSLTQLDLENLFTDCGNIITSRILYDQTTGLSKGVGFIRFDQRIEAERAIQKL 75

Query: 354 NGRI 357
           N  I
Sbjct: 74  NNHI 63

 Score = 53.9 bits (128), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 34/129 (26%), Positives = 69/129 (53%), Gaps = 3/129 (2%)
 Frame = -2

Query: 127 SCKVVCDE--NGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKEREAELG 184
           +CK++ D+    S GY FV+++ QE ADKAI  +NG+ L ++ + V    +R   E+  G
Sbjct: 434 TCKLIRDKPTGQSLGYGFVNYKRQEDADKAIHTLNGLRLQNKTIKVSL--ARPSCESIKG 261

Query: 185 AKAKEFTNVYIKNFGEEVDDGNLKELFSQFGKTLSVKVMRDXXXXXXXXXX-VSYEKHED 243
           A      N+YI    + +   +L+ LF+  G  ++ +++ D           + +++  +
Sbjct: 260 A------NLYISGLPKSLTQLDLENLFTDCGNIITSRILYDQTTGLSKGVGFIRFDQRIE 99

Query: 244 ANKAVEEMN 252
           A +A++++N
Sbjct: 98  AERAIQKLN 72

 Score = 33.9 bits (76), Expect = 0.22,   Method: Compositional matrix adjust.
 Identities = 16/40 (40%), Positives = 27/40 (67%)
 Frame = -2

Query: 330 GRSKGFGFVCFSSPEEATKAVTEMNGRIVGSKPLYVALAQ 369
           G+S G+GFV +   E+A KA+  +NG  + +K + V+LA+
Sbjct: 404 GQSLGYGFVNYKRQEDADKAIHTLNGLRLQNKTIKVSLAR 285
>17681
          Length = 964

 Score = 73.6 bits (179), Expect = 2e-13,   Method: Compositional matrix adjust.
 Identities = 59/205 (28%), Positives = 90/205 (43%), Gaps = 45/205 (21%)
 Frame = +2

Query: 13  LYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDTM 72
           ++VGDL  ++    L E F+P G + + R+ RD  T +S GYA+V+F + A+AE A+  M
Sbjct: 38  IFVGDLSPEIETETLREAFAPFGEISNCRIVRDPQTMKSKGYAFVSFVKKAEAENAIQAM 217

Query: 73  NFDVMKGKPIRIMWSQRD-PSLRKSG-----------------VGNVFIKNLDKS----- 109
           N   +  + IR  WS R  P  R+S                       IKN  +      
Sbjct: 218 NGQWIGSRSIRTNWSTRKLPPPRESSKSGGQGGGMGGMGGCGGGAGNGIKNNQRHTFEEV 397

Query: 110 --------------------IDNKALYDTFSAFGNILSCKVVCDENGSKGYAFVHFETQE 149
                               I ++ ++  F  FG I   +V  D    KG+AF+ F T+E
Sbjct: 398 YNQSSPTNTTVYCGGFPPNVISDELMHKHFMQFGPIQDVRVFKD----KGFAFIKFVTKE 565

Query: 150 AADKAIE--KMNGMLLNDRKVFVGR 172
           AA +AIE   ++ +  N  K F G+
Sbjct: 566 AAARAIEHTHISEVHGNHVKCFWGK 640

 Score = 56.6 bits (135), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 26/79 (32%), Positives = 47/79 (59%), Gaps = 2/79 (2%)
 Frame = +2

Query: 295 NLYIKNLDDTIDDEKLRREFSPFGSITSAKVMLE--DGRSKGFGFVCFSSPEEATKAVTE 352
           ++++ +L   I+ E LR  F+PFG I++ +++ +    +SKG+ FV F    EA  A+  
Sbjct: 35  HIFVGDLSPEIETETLREAFAPFGEISNCRIVRDPQTMKSKGYAFVSFVKKAEAENAIQA 214

Query: 353 MNGRIVGSKPLYVALAQRK 371
           MNG+ +GS+ +    + RK
Sbjct: 215 MNGQWIGSRSIRTNWSTRK 271

 Score = 55.5 bits (132), Expect = 8e-08,   Method: Compositional matrix adjust.
 Identities = 28/80 (35%), Positives = 44/80 (55%), Gaps = 2/80 (2%)
 Frame = +2

Query: 91  PSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENG--SKGYAFVHFETQ 148
           P    S   ++F+ +L   I+ + L + F+ FG I +C++V D     SKGYAFV F  +
Sbjct: 8   PKTDISSHHHIFVGDLSPEIETETLREAFAPFGEISNCRIVRDPQTMKSKGYAFVSFVKK 187

Query: 149 EAADKAIEKMNGMLLNDRKV 168
             A+ AI+ MNG  +  R +
Sbjct: 188 AEAENAIQAMNGQWIGSRSI 247
>20488
          Length = 3281

 Score = 67.0 bits (162), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 35/84 (41%), Positives = 49/84 (58%), Gaps = 2/84 (2%)
 Frame = +2

Query: 293  GVNLYIKNLDDTIDDEKLRREFSPFGSITSAKVMLE--DGRSKGFGFVCFSSPEEATKAV 350
            G NL+I +L     D+ L + F PFG++ SAKV ++     SK FGFV + SP  A  A+
Sbjct: 2705 GANLFIYHLPQEFGDQDLMQMFMPFGNVVSAKVFIDKQTNLSKCFGFVSYDSPLAAQAAI 2884

Query: 351  TEMNGRIVGSKPLYVALAQRKEER 374
            T MNG  +G K L V L + K ++
Sbjct: 2885 TSMNGFQIGMKRLKVQLKRSKNDK 2956

 Score = 48.5 bits (114), Expect = 9e-06,   Method: Compositional matrix adjust.
 Identities = 27/82 (32%), Positives = 47/82 (57%), Gaps = 2/82 (2%)
 Frame = +2

Query: 100  NVFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDE--NGSKGYAFVHFETQEAADKAIEK 157
            N+FI +L +   ++ L   F  FGN++S KV  D+  N SK + FV +++  AA  AI  
Sbjct: 2711 NLFIYHLPQEFGDQDLMQMFMPFGNVVSAKVFIDKQTNLSKCFGFVSYDSPLAAQAAITS 2890

Query: 158  MNGMLLNDRKVFVGRFKSRKER 179
            MNG  +  +++ V   +S+ ++
Sbjct: 2891 MNGFQIGMKRLKVQLKRSKNDK 2956

 Score = 34.7 bits (78), Expect = 0.11,   Method: Compositional matrix adjust.
 Identities = 23/82 (28%), Positives = 39/82 (47%), Gaps = 1/82 (1%)
 Frame = +2

Query: 192  NVYIKNFGEEVDDGNLKELFSQFGKTLSVKVMRDXXXXXXXXX-XVSYEKHEDANKAVEE 250
            N++I +  +E  D +L ++F  FG  +S KV  D           VSY+    A  A+  
Sbjct: 2711 NLFIYHLPQEFGDQDLMQMFMPFGNVVSAKVFIDKQTNLSKCFGFVSYDSPLAAQAAITS 2890

Query: 251  MNGKEMSGKAIFVGRAQKKVER 272
            MNG ++  K + V   + K ++
Sbjct: 2891 MNGFQIGMKRLKVQLKRSKNDK 2956
>03744
          Length = 3486

 Score = 67.0 bits (162), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 36/90 (40%), Positives = 51/90 (56%), Gaps = 2/90 (2%)
 Frame = -1

Query: 287  RISRYQGVNLYIKNLDDTIDDEKLRREFSPFGSITSAKVMLED--GRSKGFGFVCFSSPE 344
            R+    G NL+I +L     D+ L + F PFG++ SAKV ++     SK FGFV + SP 
Sbjct: 3237 RVPGPDGANLFIYHLPQEFGDQDLMQMFMPFGNVVSAKVFIDKQTNLSKCFGFVSYDSPL 3058

Query: 345  EATKAVTEMNGRIVGSKPLYVALAQRKEER 374
             A  A+T MNG  +G K L V L + K ++
Sbjct: 3057 AAQAAITSMNGFQIGMKRLKVQLKRSKNDK 2968

 Score = 49.3 bits (116), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 27/82 (32%), Positives = 47/82 (57%), Gaps = 2/82 (2%)
 Frame = -1

Query: 100  NVFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDE--NGSKGYAFVHFETQEAADKAIEK 157
            N+FI +L +   ++ L   F  FGN++S KV  D+  N SK + FV +++  AA  AI  
Sbjct: 3213 NLFIYHLPQEFGDQDLMQMFMPFGNVVSAKVFIDKQTNLSKCFGFVSYDSPLAAQAAITS 3034

Query: 158  MNGMLLNDRKVFVGRFKSRKER 179
            MNG  +  +++ V   +S+ ++
Sbjct: 3033 MNGFQIGMKRLKVQLKRSKNDK 2968

 Score = 35.4 bits (80), Expect = 0.076,   Method: Compositional matrix adjust.
 Identities = 23/83 (27%), Positives = 39/83 (46%), Gaps = 1/83 (1%)
 Frame = -1

Query: 191  TNVYIKNFGEEVDDGNLKELFSQFGKTLSVKVMRDXXXXXXXXX-XVSYEKHEDANKAVE 249
             N++I +  +E  D +L ++F  FG  +S KV  D           VSY+    A  A+ 
Sbjct: 3216 ANLFIYHLPQEFGDQDLMQMFMPFGNVVSAKVFIDKQTNLSKCFGFVSYDSPLAAQAAIT 3037

Query: 250  EMNGKEMSGKAIFVGRAQKKVER 272
             MNG ++  K + V   + K ++
Sbjct: 3036 SMNGFQIGMKRLKVQLKRSKNDK 2968
>28652
          Length = 918

 Score = 66.2 bits (160), Expect = 3e-11,   Method: Compositional matrix adjust.
 Identities = 64/269 (23%), Positives = 120/269 (44%), Gaps = 18/269 (6%)
 Frame = -2

Query: 13  LYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDTM 72
           ++ G +  D+ E  L   F   G +  +R+  D ++  + GY +V +     A  A+   
Sbjct: 725 VFCGKIPRDIFEDELIPLFEDCGTIWDLRLMMDPVSNLNRGYCFVTYTTKEAAAEAVKQH 546

Query: 73  N-FDVMKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFGNILSCKVV 131
           + +++ KGK +++  S   P+LR      +F+ N+ KS   + +   F      L   +V
Sbjct: 545 DGYEIRKGKKLKVNISI--PNLR------LFVGNIPKSKTKEEILKEFEKHSEGLMDVIV 390

Query: 132 CDENGS-----KGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKS----------- 175
                +     +G+AF+ ++T + A  A           R+   GRF+            
Sbjct: 389 YGSADNPKLKNRGFAFLEYDTHKNASAA----------KRRFTTGRFRVWQCDVIVDWAD 240

Query: 176 -RKEREAELGAKAKEFTNVYIKNFGEEVDDGNLKELFSQFGKTLSVKVMRDXXXXXXXXX 234
            ++E   E  +K K    +Y++N   +V + +LKE F  +GK   VK ++D         
Sbjct: 239 LQEEPNEETMSKVKV---LYVRNLTGDVTEDDLKEKFGAYGKVERVKKIKD-------YG 90

Query: 235 XVSYEKHEDANKAVEEMNGKEMSGKAIFV 263
            V YE  EDA KA+++++G+++    I V
Sbjct: 89  FVHYEDREDALKALDDLHGEKIGNLEIDV 3
>11687
          Length = 676

 Score = 62.4 bits (150), Expect = 5e-10,   Method: Compositional matrix adjust.
 Identities = 46/156 (29%), Positives = 80/156 (51%), Gaps = 9/156 (5%)
 Frame = +3

Query: 13  LYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNF---QQPADAERAL 69
           ++VG +  ++ E  L + F   GPV S+ + RD  T +S G  +V F   +   DA+ AL
Sbjct: 156 MFVGQIPRNMDENELRKMFEDYGPVHSLNILRDKNTGQSKGCCFVTFFTRKAALDAQNAL 335

Query: 70  DTMNFDVMKGKPIRIMWSQRDPSLRKSGVGNV-----FIKNLDKSIDNKALYDTFSAFGN 124
             +    M   P+++  +    S +++G  NV     F+  L K +    +   F +FG+
Sbjct: 336 HNVKTMPMMHHPVQMKPAD---SEKRNGERNVEERKLFVGMLSKKLSENDVRMLFESFGS 506

Query: 125 ILSCKVVCDENG-SKGYAFVHFETQEAADKAIEKMN 159
           I  C V+ D NG S+G AF+ F +++ A  +I+ M+
Sbjct: 507 IDDCTVLRDSNGTSRGCAFITFASRQCAMNSIKGMH 614
>08958
          Length = 680

 Score = 60.5 bits (145), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 45/154 (29%), Positives = 78/154 (50%), Gaps = 3/154 (1%)
 Frame = +2

Query: 13  LYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERA-LDT 71
           L+VG+L  DV+E    + FSP G V    V     + R  G+  ++++  A+A +A LD 
Sbjct: 74  LFVGNLTPDVSEDDFKKLFSPFGEVSEAYVN----SGRGFGFIRLDYRHNAEAAKAALDG 241

Query: 72  MNFDVMKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFGNILSCKVV 131
           +     KG+ +R+ ++    +L+        +KNL   + N+ L   F+ FG++    V+
Sbjct: 242 LQ---RKGRSLRVRYATHGAALK--------VKNLHPYVSNELLEQAFTQFGDLERAIVI 388

Query: 132 CDENG-SKGYAFVHFETQEAADKAIEKMN-GMLL 163
            DE G S G   V F  +  A +A+ ++N G+ L
Sbjct: 389 VDERGRSTGEGVVEFVRKPGAQQALRRINEGVFL 490

 Score = 38.9 bits (89), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 36/157 (22%), Positives = 62/157 (39%)
 Frame = +2

Query: 96  SGVGNVFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENGSKGYAFVHFETQEAADKAI 155
           +G   +F+ NL   +        FS FG +    V    N  +G+ F+  + +  A+ A 
Sbjct: 59  TGRCRLFVGNLTPDVSEDDFKKLFSPFGEVSEAYV----NSGRGFGFIRLDYRHNAEAAK 226

Query: 156 EKMNGMLLNDRKVFVGRFKSRKEREAELGAKAKEFTNVYIKNFGEEVDDGNLKELFSQFG 215
             ++G+    R + V        R A  GA  K      +KN    V +  L++ F+QFG
Sbjct: 227 AALDGLQRKGRSLRV--------RYATHGAALK------VKNLHPYVSNELLEQAFTQFG 364

Query: 216 KTLSVKVMRDXXXXXXXXXXVSYEKHEDANKAVEEMN 252
                 V+ D          V + +   A +A+  +N
Sbjct: 365 DLERAIVIVDERGRSTGEGVVEFVRKPGAQQALRRIN 475
>16427
          Length = 1313

 Score = 58.5 bits (140), Expect = 9e-09,   Method: Compositional matrix adjust.
 Identities = 32/77 (41%), Positives = 49/77 (63%), Gaps = 2/77 (2%)
 Frame = +1

Query: 296 LYIKNLDDTIDDEKLRREFSPFGSITSAKVMLEDGR--SKGFGFVCFSSPEEATKAVTEM 353
           L++  L + ID++ L REFS FG IT + V+ +  R  S+GFGFV + +P +A +AV  M
Sbjct: 142 LFVGGLAEEIDEKVLEREFSKFGRITESMVIRDKVRQVSRGFGFVTYENPMDAEEAVKHM 321

Query: 354 NGRIVGSKPLYVALAQR 370
           +G+ +  K L+V  A R
Sbjct: 322 DGKEILGKKLHVEDAVR 372

 Score = 46.6 bits (109), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 25/72 (34%), Positives = 40/72 (55%), Gaps = 1/72 (1%)
 Frame = +1

Query: 193 VYIKNFGEEVDDGNLKELFSQFGKTLSVKVMRDXXXXXXXXXX-VSYEKHEDANKAVEEM 251
           +++    EE+D+  L+  FS+FG+     V+RD           V+YE   DA +AV+ M
Sbjct: 142 LFVGGLAEEIDEKVLEREFSKFGRITESMVIRDKVRQVSRGFGFVTYENPMDAEEAVKHM 321

Query: 252 NGKEMSGKAIFV 263
           +GKE+ GK + V
Sbjct: 322 DGKEILGKKLHV 357
>30672
          Length = 877

 Score = 56.6 bits (135), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 39/109 (35%), Positives = 59/109 (54%), Gaps = 1/109 (0%)
 Frame = +3

Query: 277 KRKFEQLKQERISRYQGVNLYIKNLDDTIDDEKLRREFSPFGSITSAKVMLEDG-RSKGF 335
           K+K +Q KQE   R     L I+NL     +  +R  F  FG+I+   + L+ G RS+GF
Sbjct: 363 KKKTKQPKQELGKR---CRLIIRNLAFKCKEADIRSHFGKFGTISEVTIPLKQGDRSRGF 533

Query: 336 GFVCFSSPEEATKAVTEMNGRIVGSKPLYVALAQRKEERKAHLTNQYMQ 384
            FV F+  + A KA+++MNG  +  +P+ V  A  K+  +A  T Q  Q
Sbjct: 534 AFVQFTEVKAAQKAISDMNGTAIMDRPVAVDWAVAKDRFEAS-TQQNQQ 677

 Score = 47.4 bits (111), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 48/205 (23%), Positives = 75/205 (36%), Gaps = 46/205 (22%)
 Frame = +3

Query: 12  SLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDT 71
           +L+V +L  + +   L E F   GP+ +  V       +  G+ YV F    DA +A DT
Sbjct: 15  TLFVRNLPFETSNEKLLEAFEQVGPLKTAFVVAGKEPGKCRGFGYVQFSMLEDAIKAKDT 194

Query: 72  MNFDVMKGKPIRIMWSQRDPSLRKS-----------GVGN-------------------- 100
           +      G+ I + ++    S +             G+G                     
Sbjct: 195 VTH--CSGRKISLSFADTKKSWKTKQKGGTETSDALGLGKKLPSQTAVTDGEPNPKPEKK 368

Query: 101 --------------VFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDE-NGSKGYAFVHF 145
                         + I+NL        +   F  FG I    +   + + S+G+AFV F
Sbjct: 369 KTKQPKQELGKRCRLIIRNLAFKCKEADIRSHFGKFGTISEVTIPLKQGDRSRGFAFVQF 548

Query: 146 ETQEAADKAIEKMNGMLLNDRKVFV 170
              +AA KAI  MNG  + DR V V
Sbjct: 549 TEVKAAQKAISDMNGTAIMDRPVAV 623

 Score = 42.4 bits (98), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 27/72 (37%), Positives = 40/72 (55%), Gaps = 5/72 (6%)
 Frame = +3

Query: 292 QGVNLYIKNLDDTIDDEKLRREFSPFGSITSAKVML--EDGRSKGFGFVCFSSPEEATKA 349
           Q   L+++NL     +EKL   F   G + +A V+   E G+ +GFG+V FS  E+A KA
Sbjct: 6   QSKTLFVRNLPFETSNEKLLEAFEQVGPLKTAFVVAGKEPGKCRGFGYVQFSMLEDAIKA 185

Query: 350 ---VTEMNGRIV 358
              VT  +GR +
Sbjct: 186 KDTVTHCSGRKI 221

 Score = 28.5 bits (62), Expect = 8.3,   Method: Compositional matrix adjust.
 Identities = 20/93 (21%), Positives = 41/93 (44%)
 Frame = +3

Query: 174 KSRKEREAELGAKAKEFTNVYIKNFGEEVDDGNLKELFSQFGKTLSVKVMRDXXXXXXXX 233
           K  K+ + ELG + +    + I+N   +  + +++  F +FG    V +           
Sbjct: 366 KKTKQPKQELGKRCR----LIIRNLAFKCKEADIRSHFGKFGTISEVTIPLKQGDRSRGF 533

Query: 234 XXVSYEKHEDANKAVEEMNGKEMSGKAIFVGRA 266
             V + + + A KA+ +MNG  +  + + V  A
Sbjct: 534 AFVQFTEVKAAQKAISDMNGTAIMDRPVAVDWA 632
>14258
          Length = 1063

 Score = 55.8 bits (133), Expect = 5e-08,   Method: Compositional matrix adjust.
 Identities = 29/72 (40%), Positives = 43/72 (59%), Gaps = 2/72 (2%)
 Frame = +2

Query: 305 IDDEKLRREFSPFGSITSAKVMLED--GRSKGFGFVCFSSPEEATKAVTEMNGRIVGSKP 362
           + D+ L + F PFG++ SAKV ++     SK FGFV + SP  A  A++ MNG  +G K 
Sbjct: 95  VGDQDLMQMFMPFGNVISAKVFIDKQTNLSKCFGFVSYDSPMSAQDAISSMNGFQIGMKR 274

Query: 363 LYVALAQRKEER 374
           L V L + K ++
Sbjct: 275 LKVQLKRPKNDK 310

 Score = 30.0 bits (66), Expect = 3.0,   Method: Compositional matrix adjust.
 Identities = 19/61 (31%), Positives = 28/61 (45%), Gaps = 1/61 (1%)
 Frame = +2

Query: 202 VDDGNLKELFSQFGKTLSVKVMRDXXXXXXXXX-XVSYEKHEDANKAVEEMNGKEMSGKA 260
           V D +L ++F  FG  +S KV  D           VSY+    A  A+  MNG ++  K 
Sbjct: 95  VGDQDLMQMFMPFGNVISAKVFIDKQTNLSKCFGFVSYDSPMSAQDAISSMNGFQIGMKR 274

Query: 261 I 261
           +
Sbjct: 275 L 277
>14637
          Length = 455

 Score = 55.8 bits (133), Expect = 6e-08,   Method: Compositional matrix adjust.
 Identities = 28/65 (43%), Positives = 39/65 (60%), Gaps = 2/65 (3%)
 Frame = -1

Query: 293 GVNLYIKNLDDTIDDEKLRREFSPFGSITSAKVMLE--DGRSKGFGFVCFSSPEEATKAV 350
           G NL+I +L     D+ L + F PFG++ SAKV ++     SK FGFV + SP  A  A+
Sbjct: 206 GSNLFIYHLPQEFGDQDLMQMFMPFGNVISAKVFIDKQTNLSKCFGFVSYDSPMSAQDAI 27

Query: 351 TEMNG 355
           + MNG
Sbjct: 26  SSMNG 12

 Score = 45.8 bits (107), Expect = 6e-05,   Method: Compositional matrix adjust.
 Identities = 25/66 (37%), Positives = 38/66 (57%), Gaps = 2/66 (3%)
 Frame = -1

Query: 100 NVFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDE--NGSKGYAFVHFETQEAADKAIEK 157
           N+FI +L +   ++ L   F  FGN++S KV  D+  N SK + FV +++  +A  AI  
Sbjct: 200 NLFIYHLPQEFGDQDLMQMFMPFGNVISAKVFIDKQTNLSKCFGFVSYDSPMSAQDAISS 21

Query: 158 MNGMLL 163
           MNG  L
Sbjct: 20  MNGFRL 3
>02343
          Length = 1715

 Score = 55.5 bits (132), Expect = 7e-08,   Method: Compositional matrix adjust.
 Identities = 36/155 (23%), Positives = 70/155 (45%), Gaps = 1/155 (0%)
 Frame = -2

Query: 11   ASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALD 70
             +LY+  L  + T+  L       G + S +   D  T +  GY +V+F  P  AERA+ 
Sbjct: 1264 TNLYIRGLSPNTTDKDLVNLCQHFGTITSTKAIIDQTTNKCKGYGFVDFDAPGAAERAVQ 1085

Query: 71   TMNFDVMKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFGNILSCKV 130
             +    ++ +  +    ++DP+       N++I NL      K L   F  +G ++S ++
Sbjct: 1084 ALQAQGIQAQMAK--QQEQDPT-------NLYIANLPLHFTEKHLEGLFKDYGTVISTRI 932

Query: 131  VCDENG-SKGYAFVHFETQEAADKAIEKMNGMLLN 164
            +   +G S+   F   E+++  D  I   N  +++
Sbjct: 931  LRKPDGISRCVGFARMESRDKCDTVINTFNNKMIS 827

 Score = 45.8 bits (107), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 26/87 (29%), Positives = 47/87 (54%), Gaps = 2/87 (2%)
 Frame = -2

Query: 294  VNLYIKNLDDTIDDEKLRREFSPFGSITSAKVMLED--GRSKGFGFVCFSSPEEATKAVT 351
             NLYI+ L     D+ L      FG+ITS K +++    + KG+GFV F +P  A +AV 
Sbjct: 1264 TNLYIRGLSPNTTDKDLVNLCQHFGTITSTKAIIDQTTNKCKGYGFVDFDAPGAAERAVQ 1085

Query: 352  EMNGRIVGSKPLYVALAQRKEERKAHL 378
             +  + + ++     +A+++E+   +L
Sbjct: 1084 ALQAQGIQAQ-----MAKQQEQDPTNL 1019
>13457
          Length = 4857

 Score = 38.5 bits (88), Expect(2) = 2e-07,   Method: Compositional matrix adjust.
 Identities = 20/56 (35%), Positives = 32/56 (57%), Gaps = 1/56 (1%)
 Frame = -3

Query: 274  AELKRKFEQLKQERISRY-QGVNLYIKNLDDTIDDEKLRREFSPFGSITSAKVMLE 328
            A+ +RK    + E   R  +G NL+I +L     D +L + F PFG++ SAKV ++
Sbjct: 2485 ADAQRKIVLERAELTDRGPEGCNLFIYHLPQXXGDAELAQMFVPFGNVISAKVYVD 2318

 Score = 35.0 bits (79), Expect(2) = 2e-07,   Method: Compositional matrix adjust.
 Identities = 17/43 (39%), Positives = 24/43 (55%)
 Frame = -2

Query: 335  FGFVCFSSPEEATKAVTEMNGRIVGSKPLYVALAQRKEERKAH 377
            FGFV F +P  A  A+  MNG  +G K L V L + K+  + +
Sbjct: 2294 FGFVSFDNPASAQAAIQAMNGFQIGMKRLKVQLKRPKDANRPY 2166

 Score = 44.7 bits (104), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 23/77 (29%), Positives = 38/77 (49%), Gaps = 1/77 (1%)
 Frame = -1

Query: 85   MWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENG-SKGYAFV 143
            +W +  P +       +F+  L+K    + +   F  +G I  C ++ D+NG SKG AFV
Sbjct: 3450 VWCRLTPKMTIGEDRKLFVGMLNKQQTEEDVRQLFHPYGAIEECTILRDQNGNSKGCAFV 3271

Query: 144  HFETQEAADKAIEKMNG 160
             + T   A  AI  ++G
Sbjct: 3270 KYSTHSEAQAAINALHG 3220

 Score = 31.6 bits (70), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 13/34 (38%), Positives = 19/34 (55%)
 Frame = -3

Query: 100  NVFIKNLDKSIDNKALYDTFSAFGNILSCKVVCD 133
            N+FI +L +   +  L   F  FGN++S KV  D
Sbjct: 2419 NLFIYHLPQXXGDAELAQMFVPFGNVISAKVYVD 2318
>13822
          Length = 963

 Score = 53.5 bits (127), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 32/104 (30%), Positives = 52/104 (50%), Gaps = 4/104 (3%)
 Frame = -1

Query: 266 AQKKVERQAELKRKFE----QLKQERISRYQGVNLYIKNLDDTIDDEKLRREFSPFGSIT 321
           A   VE+  E+    E    Q+  + IS      L++ N+     +  LR+   PFG+I 
Sbjct: 438 ANGTVEQSTEVNSDGEVQGVQVPPQAISPEGPKRLHVSNIPFRFREADLRQLLGPFGTIL 259

Query: 322 SAKVMLEDGRSKGFGFVCFSSPEEATKAVTEMNGRIVGSKPLYV 365
             +++  +  SKGFGFV F+   EA +A  +MNG +V  + + V
Sbjct: 258 DVEIIFNERGSKGFGFVTFAHSAEAERARDKMNGTVVEGRKIEV 127

 Score = 51.2 bits (121), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 25/85 (29%), Positives = 42/85 (49%)
 Frame = -1

Query: 92  SLRKSGVGNVFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENGSKGYAFVHFETQEAA 151
           ++   G   + + N+        L      FG IL  +++ +E GSKG+ FV F     A
Sbjct: 363 AISPEGPKRLHVSNIPFRFREADLRQLLGPFGTILDVEIIFNERGSKGFGFVTFAHSAEA 184

Query: 152 DKAIEKMNGMLLNDRKVFVGRFKSR 176
           ++A +KMNG ++  RK+ V    +R
Sbjct: 183 ERARDKMNGTVVEGRKIEVNNATAR 109
>31310
          Length = 469

 Score = 52.4 bits (124), Expect = 5e-07,   Method: Compositional matrix adjust.
 Identities = 22/75 (29%), Positives = 45/75 (60%)
 Frame = -3

Query: 10  MASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERAL 69
           M  +YVG ++ ++ E  + + F P GP+ S+ +  D IT +  G++++ +  P  A+ AL
Sbjct: 326 MCRIYVGSINFEIREDTIKQAFLPFGPIKSVNLSWDPITNKHKGFSFIEYDVPEAAQLAL 147

Query: 70  DTMNFDVMKGKPIRI 84
           + MN  ++ G+ I++
Sbjct: 146 EQMNGVMIGGRNIKV 102

 Score = 49.7 bits (117), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 27/100 (27%), Positives = 53/100 (53%), Gaps = 5/100 (5%)
 Frame = -3

Query: 101 VFIKNLDKSIDNKALYDTFSAFGNILSCKVVCD--ENGSKGYAFVHFETQEAADKAIEKM 158
           +++ +++  I    +   F  FG I S  +  D   N  KG++F+ ++  EAA  A+E+M
Sbjct: 317 IYVGSINFEIREDTIKQAFLPFGPIKSVNLSWDPITNKHKGFSFIEYDVPEAAQLALEQM 138

Query: 159 NGMLLNDRKVFVGRFKSRKERE---AELGAKAKEFTNVYI 195
           NG+++  R + VGR  +  + +    +L  +A  +  +YI
Sbjct: 137 NGVMIGGRNIKVGRPSNMPQAQPIIEQLAMEATHYFRIYI 18

 Score = 47.0 bits (110), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 21/72 (29%), Positives = 42/72 (58%), Gaps = 2/72 (2%)
 Frame = -3

Query: 296 LYIKNLDDTIDDEKLRREFSPFGSITSAKVMLE--DGRSKGFGFVCFSSPEEATKAVTEM 353
           +Y+ +++  I ++ +++ F PFG I S  +  +    + KGF F+ +  PE A  A+ +M
Sbjct: 317 IYVGSINFEIREDTIKQAFLPFGPIKSVNLSWDPITNKHKGFSFIEYDVPEAAQLALEQM 138

Query: 354 NGRIVGSKPLYV 365
           NG ++G + + V
Sbjct: 137 NGVMIGGRNIKV 102

 Score = 36.2 bits (82), Expect = 0.042,   Method: Compositional matrix adjust.
 Identities = 22/74 (29%), Positives = 36/74 (48%), Gaps = 1/74 (1%)
 Frame = -3

Query: 193 VYIKNFGEEVDDGNLKELFSQFGKTLSVKVMRD-XXXXXXXXXXVSYEKHEDANKAVEEM 251
           +Y+ +   E+ +  +K+ F  FG   SV +  D           + Y+  E A  A+E+M
Sbjct: 317 IYVGSINFEIREDTIKQAFLPFGPIKSVNLSWDPITNKHKGFSFIEYDVPEAAQLALEQM 138

Query: 252 NGKEMSGKAIFVGR 265
           NG  + G+ I VGR
Sbjct: 137 NGVMIGGRNIKVGR 96
>01278
          Length = 1082

 Score = 52.0 bits (123), Expect = 7e-07,   Method: Compositional matrix adjust.
 Identities = 23/59 (38%), Positives = 37/59 (62%)
 Frame = +2

Query: 11  ASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERAL 69
           A++ V +L  D  E+ L E F P GP+  I + +D +T +S G+A++NF +  DA RA+
Sbjct: 635 ATIRVTNLSEDTRESDLQELFRPFGPISRIYLAKDKVTGQSKGFAFINFHRREDASRAI 811

 Score = 35.8 bits (81), Expect = 0.052,   Method: Compositional matrix adjust.
 Identities = 23/78 (29%), Positives = 38/78 (48%), Gaps = 7/78 (8%)
 Frame = +2

Query: 94  RKSGVGNVFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDE--NGSKGYAFVHFETQEAA 151
           RK     + + NL +      L + F  FG I    +  D+    SKG+AF++F  +E A
Sbjct: 620 RKDEAATIRVTNLSEDTRESDLQELFRPFGPISRIYLAKDKVTGQSKGFAFINFHRREDA 799

Query: 152 DKAIEKMNG-----MLLN 164
            +AI  ++G     ++LN
Sbjct: 800 SRAIAGVSGFGYDHLILN 853
>02502
          Length = 1557

 Score = 50.4 bits (119), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 32/117 (27%), Positives = 57/117 (48%), Gaps = 18/117 (15%)
 Frame = -3

Query: 80   KPIRIMWSQRDP-------SLRKSGVGNVFIKN-----------LDKSIDNKALYDTFSA 121
            +PIR  W+ R P       S+R+     VF ++           ++  +  + +++TF  
Sbjct: 1552 RPIRTNWATRKPLAPIAKDSVRQLSYDEVFNQSSQTNCTVYCGGVNNGLTEELMHNTFKD 1373

Query: 122  FGNILSCKVVCDENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKE 178
            FG+IL  ++  D    KG+AF+ F  ++AA  AI  ++G ++ND+ V     K   E
Sbjct: 1372 FGSILEVRIFKD----KGFAFIRFNNKDAATNAICTIHGTVINDQVVRCSWGKESNE 1214
>02140
          Length = 1796

 Score = 49.7 bits (117), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 26/72 (36%), Positives = 41/72 (56%), Gaps = 2/72 (2%)
 Frame = +3

Query: 101 VFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENGSKG--YAFVHFETQEAADKAIEKM 158
           +F+  L+    ++ L   FS FG I SC+V+ D    +   YAFV FE  E  + A  KM
Sbjct: 807 LFVCKLNPVTTDEDLEMIFSRFGPITSCEVIRDHKTKESLQYAFVEFEKPEHCENAYFKM 986

Query: 159 NGMLLNDRKVFV 170
           + +L++DR++ V
Sbjct: 987 DNVLIDDRRIHV 1022

 Score = 49.3 bits (116), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 29/85 (34%), Positives = 44/85 (51%)
 Frame = +3

Query: 4   AASSYPMASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPA 63
           A +  P   L+V  L+   T+  L   FS  GP+ S  V RD  T+ SL YA+V F++P 
Sbjct: 780 ADTKPPDNVLFVCKLNPVTTDEDLEMIFSRFGPITSCEVIRDHKTKESLQYAFVEFEKPE 959

Query: 64  DAERALDTMNFDVMKGKPIRIMWSQ 88
             E A   M+  ++  + I + +SQ
Sbjct: 960 HCENAYFKMDNVLIDDRRIHVDFSQ 1034
>28455
          Length = 573

 Score = 48.5 bits (114), Expect = 9e-06,   Method: Compositional matrix adjust.
 Identities = 25/72 (34%), Positives = 41/72 (56%), Gaps = 1/72 (1%)
 Frame = -1

Query: 101 VFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENG-SKGYAFVHFETQEAADKAIEKMN 159
           +F+KNL  +   +AL   F   G +   ++V   +G SKG A+V FET+E A +A+ K +
Sbjct: 534 LFVKNLPFTCSAEALETIFKEHGKVKDVRLVTYRSGASKGLAYVEFETEEMATQAVMKTD 355

Query: 160 GMLLNDRKVFVG 171
           G+ + D  + V 
Sbjct: 354 GLQVGDHMISVA 319
>19868
          Length = 434

 Score = 47.8 bits (112), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 32/135 (23%), Positives = 62/135 (45%), Gaps = 4/135 (2%)
 Frame = +2

Query: 13  LYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDTM 72
           ++VG L    +   L + F+  G +  + V +D  TRRS G+ ++ F  PA  ++ L   
Sbjct: 5   MFVGGLSWQTSPESLRDYFNKFGEITEVMVMKDPTTRRSRGFGFITFGDPASVDKVLAQA 184

Query: 73  NFDVMKGKPI--RIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFGNILSCKV 130
             + + GK I  ++ + +R      +    +F+  L      + + + F  FG I    +
Sbjct: 185 THE-LDGKKIDPKVAFPRRAHPRMVTRTKKIFVGGLSAPTTLEDVKNYFEQFGPIEDAML 361

Query: 131 VCDE--NGSKGYAFV 143
           + D+  N  +G+ FV
Sbjct: 362 MFDKQTNRHRGFGFV 406

 Score = 42.0 bits (97), Expect = 8e-04,   Method: Compositional matrix adjust.
 Identities = 32/102 (31%), Positives = 46/102 (45%), Gaps = 6/102 (5%)
 Frame = +2

Query: 296 LYIKNLDDTIDDEKLRREFSPFGSITSAKVMLEDG--RSKGFGFVCFSSPEEATK----A 349
           +++  L      E LR  F+ FG IT   VM +    RS+GFGF+ F  P    K    A
Sbjct: 5   MFVGGLSWQTSPESLRDYFNKFGEITEVMVMKDPTTRRSRGFGFITFGDPASVDKVLAQA 184

Query: 350 VTEMNGRIVGSKPLYVALAQRKEERKAHLTNQYMQRVAGMRA 391
             E++G+ +  K   VA  +R   R    T +    V G+ A
Sbjct: 185 THELDGKKIDPK---VAFPRRAHPRMVTRTKKIF--VGGLSA 295

 Score = 37.0 bits (84), Expect = 0.023,   Method: Compositional matrix adjust.
 Identities = 33/143 (23%), Positives = 61/143 (42%), Gaps = 7/143 (4%)
 Frame = +2

Query: 206 NLKELFSQFGKTLSVKVMRD-XXXXXXXXXXVSYEKHEDANK----AVEEMNGKEMSGKA 260
           +L++ F++FG+   V VM+D           +++      +K    A  E++GK++  K 
Sbjct: 44  SLRDYFNKFGEITEVMVMKDPTTRRSRGFGFITFGDPASVDKVLAQATHELDGKKIDPKV 223

Query: 261 IFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTIDDEKLRREFSPFGSI 320
            F  RA  ++                 ++R +   +++  L      E ++  F  FG I
Sbjct: 224 AFPRRAHPRM-----------------VTRTK--KIFVGGLSAPTTLEDVKNYFEQFGPI 346

Query: 321 TSAKVMLED--GRSKGFGFVCFS 341
             A +M +    R +GFGFV  S
Sbjct: 347 EDAMLMFDKQTNRHRGFGFVTIS 415
>15371
          Length = 383

 Score = 47.0 bits (110), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 23/53 (43%), Positives = 32/53 (60%), Gaps = 2/53 (3%)
 Frame = -2

Query: 293 GVNLYIKNLDDTIDDEKLRREFSPFGSITSAKVMLE--DGRSKGFGFVCFSSP 343
           G NL+I +L     D+ L + F PFG++ SAKV ++     SK FGFV + SP
Sbjct: 160 GANLFIYHLPQEFGDQDLMQMFMPFGNVVSAKVFIDKQTNLSKCFGFVSYDSP 2

 Score = 35.8 bits (81), Expect = 0.062,   Method: Compositional matrix adjust.
 Identities = 18/50 (36%), Positives = 30/50 (60%), Gaps = 2/50 (4%)
 Frame = -2

Query: 100 NVFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDE--NGSKGYAFVHFET 147
           N+FI +L +   ++ L   F  FGN++S KV  D+  N SK + FV +++
Sbjct: 154 NLFIYHLPQEFGDQDLMQMFMPFGNVVSAKVFIDKQTNLSKCFGFVSYDS 5
>03000
          Length = 778

 Score = 47.0 bits (110), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 47/188 (25%), Positives = 84/188 (44%), Gaps = 11/188 (5%)
 Frame = +3

Query: 182 ELGAKAKEFTNVYIKNFGEEVDDGNLKELFSQFGKTLSVKVMRDXXXXXXXXXX-VSYEK 240
           +L   A++F  ++I     E D+ +L+  F  +G+ +   VMRD           ++Y+ 
Sbjct: 60  DLDPNAEQFRKLFIGGLSYETDEDSLRSHFETWGEIVDCIVMRDSNSKRSRGFGFITYKD 239

Query: 241 HEDANKAV----EEMNGKEMSGKAIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNL 296
            E  ++A      +++G+E+  K         + E Q  +K+ F            GV  
Sbjct: 240 AESIDQAQANRPHKIDGREVDTKRAMPREESGRSEVQQSVKKMF----------VGGVK- 386

Query: 297 YIKNLDDTIDDEKLRREFSPFGSITSAKVMLEDG--RSKGFGFVCFSSPEEATKAV---- 350
                +DT +D  +R  F+ FG IT   ++ + G  +++GF FV F   +   KAV    
Sbjct: 387 -----EDTTED-MIRDTFNEFGEITGVDLIQDKGTGKNRGFCFVTFGDHDSVDKAVLKKR 548

Query: 351 TEMNGRIV 358
            ++NGR V
Sbjct: 549 HDLNGRQV 572

 Score = 37.7 bits (86), Expect = 0.016,   Method: Compositional matrix adjust.
 Identities = 23/72 (31%), Positives = 36/72 (50%), Gaps = 6/72 (8%)
 Frame = +3

Query: 296 LYIKNLDDTIDDEKLRREFSPFGSITSAKVMLEDG--RSKGFGFVCFSSPEEATKAVT-- 351
           L+I  L    D++ LR  F  +G I    VM +    RS+GFGF+ +   E   +A    
Sbjct: 93  LFIGGLSYETDEDSLRSHFETWGEIVDCIVMRDSNSKRSRGFGFITYKDAESIDQAQANR 272

Query: 352 --EMNGRIVGSK 361
             +++GR V +K
Sbjct: 273 PHKIDGREVDTK 308
>02064
          Length = 1195

 Score = 47.0 bits (110), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 27/92 (29%), Positives = 49/92 (53%), Gaps = 5/92 (5%)
 Frame = +1

Query: 284 KQERISRYQGVNLYIKNLDDTIDDEKLRREFSPFGSITSAKVMLEDGRSKGFGFVCFSSP 343
           + +R++R     + +KNL   I  + LR  F   G +  +++ ++ GRS G G V F++ 
Sbjct: 49  RGQRVTRPDNCTVQVKNLPYAITWQDLRERFQEIGVVKYSEITMDKGRSTGQGLVRFATE 228

Query: 344 EEATKAVTEMN-----GRIVGSKPLYVALAQR 370
           ++A +A+  M+     GR +G K +Y    QR
Sbjct: 229 DDAVRAINSMDRTRYEGRTIGVK-MYRG*WQR 321
>00029
          Length = 2204

 Score = 46.2 bits (108), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 25/75 (33%), Positives = 39/75 (52%)
 Frame = -3

Query: 294  VNLYIKNLDDTIDDEKLRREFSPFGSITSAKVMLEDGRSKGFGFVCFSSPEEATKAVTEM 353
            + ++I NL D  D E+LR  F  +GS+    V+      K FGFV      EA  A++ +
Sbjct: 2136 IKIFIGNLGDDTDPEELRALFEKYGSVAECDVL------KNFGFVHMVKKGEADDAISNL 1975

Query: 354  NGRIVGSKPLYVALA 368
            NG  +G + + V L+
Sbjct: 1974 NGYNIGGQRMRVELS 1930

 Score = 41.6 bits (96), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 21/70 (30%), Positives = 34/70 (48%)
 Frame = -3

Query: 101  VFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENGSKGYAFVHFETQEAADKAIEKMNG 160
            +FI NL    D + L   F  +G++  C V+      K + FVH   +  AD AI  +NG
Sbjct: 2130 IFIGNLGDDTDPEELRALFEKYGSVAECDVL------KNFGFVHMVKKGEADDAISNLNG 1969

Query: 161  MLLNDRKVFV 170
              +  +++ V
Sbjct: 1968 YNIGGQRMRV 1939
>00302
          Length = 927

 Score = 44.7 bits (104), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 21/60 (35%), Positives = 38/60 (63%), Gaps = 2/60 (3%)
 Frame = -1

Query: 113 KALYDTFSAFGNILSCKVVCDENG--SKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFV 170
           + L + F  +G+I   +VV D     S+G+AFV+F++ E A +A ++ NG+ ++ RK+ V
Sbjct: 423 RGLREVFGRYGHISEVQVVYDRQTGRSRGFAFVYFKSSEDAHEAKDRCNGIEIDGRKIRV 244

 Score = 38.5 bits (88), Expect = 0.010,   Method: Compositional matrix adjust.
 Identities = 24/78 (30%), Positives = 40/78 (51%), Gaps = 2/78 (2%)
 Frame = -1

Query: 293 GVNLYIKNLDDTIDDEKLRREFSPFGSITSAKVMLE--DGRSKGFGFVCFSSPEEATKAV 350
           G++LY +       +  LR  F  +G I+  +V+ +   GRS+GF FV F S E+A +A 
Sbjct: 447 GLSLYTQ-------ERGLREVFGRYGHISEVQVVYDRQTGRSRGFAFVYFKSSEDAHEAK 289

Query: 351 TEMNGRIVGSKPLYVALA 368
              NG  +  + + V  +
Sbjct: 288 DRCNGIEIDGRKIRVDFS 235
>03903
          Length = 983

 Score = 44.3 bits (103), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 29/82 (35%), Positives = 40/82 (48%), Gaps = 8/82 (9%)
 Frame = -1

Query: 296 LYIKNLDDTIDDEKLRREFSPF--------GSITSAKVMLEDGRSKGFGFVCFSSPEEAT 347
           LYIKNL   + +E L   F  +         SI   ++M E GR KG  FV   + E+A 
Sbjct: 452 LYIKNLSKQVTEEDLHWVFGRYVNWDKEEEKSIFDIRLMKE-GRMKGQAFVTLGTEEQAR 276

Query: 348 KAVTEMNGRIVGSKPLYVALAQ 369
           KAV + N  +   KP+ V  A+
Sbjct: 275 KAVKDTNAFVFKGKPIAVHFAR 210
>28605
          Length = 697

 Score = 42.7 bits (99), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 24/69 (34%), Positives = 37/69 (53%), Gaps = 1/69 (1%)
 Frame = -3

Query: 101 VFIKNLDKSIDNKA-LYDTFSAFGNILSCKVVCDENGSKGYAFVHFETQEAADKAIEKMN 159
           VF+ NL     ++A L + FS +GN+L   V  +      Y FV F T+E   +A+E MN
Sbjct: 563 VFVANLSSDETSEAELQELFSKYGNVLDTLVHHNR-----YGFVQFSTEEEGRRAVEAMN 399

Query: 160 GMLLNDRKV 168
           G +   +K+
Sbjct: 398 GYMFYRKKL 372

 Score = 34.3 bits (77), Expect = 0.16,   Method: Compositional matrix adjust.
 Identities = 22/69 (31%), Positives = 35/69 (50%), Gaps = 1/69 (1%)
 Frame = -3

Query: 296 LYIKNLD-DTIDDEKLRREFSPFGSITSAKVMLEDGRSKGFGFVCFSSPEEATKAVTEMN 354
           +++ NL  D   + +L+  FS +G++    V         +GFV FS+ EE  +AV  MN
Sbjct: 563 VFVANLSSDETSEAELQELFSKYGNVLDTLV-----HHNRYGFVQFSTEEEGRRAVEAMN 399

Query: 355 GRIVGSKPL 363
           G +   K L
Sbjct: 398 GYMFYRKKL 372

 Score = 33.5 bits (75), Expect = 0.31,   Method: Compositional matrix adjust.
 Identities = 22/72 (30%), Positives = 35/72 (48%), Gaps = 3/72 (4%)
 Frame = -3

Query: 185 AKAKEFTN--VYIKNFG-EEVDDGNLKELFSQFGKTLSVKVMRDXXXXXXXXXXVSYEKH 241
           +K  +F N  V++ N   +E  +  L+ELFS++G  L   V  +          V +   
Sbjct: 593 SKEPKFLNSRVFVANLSSDETSEAELQELFSKYGNVLDTLVHHNRYGF------VQFSTE 432

Query: 242 EDANKAVEEMNG 253
           E+  +AVE MNG
Sbjct: 431 EEGRRAVEAMNG 396
>09736
          Length = 1319

 Score = 42.4 bits (98), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 25/63 (39%), Positives = 36/63 (57%), Gaps = 2/63 (3%)
 Frame = -2

Query: 317  FGSITSAKVMLE-DGRSKGFGFVCFSSPEEATKAVTEMNGRI-VGSKPLYVALAQRKEER 374
            + S+  AKV+L+  G+SKGFGFV FS   +  +A+ EM     +G +P+ V LA  K   
Sbjct: 1318 YRSVRGAKVVLDASGKSKGFGFVRFSEENDQQRALVEMQHMTGIGRRPIKVGLAAPKRGH 1139

Query: 375  KAH 377
              H
Sbjct: 1138 GFH 1130
>03200
          Length = 657

 Score = 42.0 bits (97), Expect = 8e-04,   Method: Compositional matrix adjust.
 Identities = 23/80 (28%), Positives = 43/80 (53%)
 Frame = -1

Query: 292 QGVNLYIKNLDDTIDDEKLRREFSPFGSITSAKVMLEDGRSKGFGFVCFSSPEEATKAVT 351
           +G  +Y+  +   + ++ L+  FS FG+I +  +     R +  GFV F   E A +A+ 
Sbjct: 492 KGHTVYVHGIG--VTEDILKSAFSNFGNIVNINI----ERERNNGFVTFEKMESADQAIA 331

Query: 352 EMNGRIVGSKPLYVALAQRK 371
            MNG ++ +  L V +A+R+
Sbjct: 330 NMNGSMISNVQLKVMMARRQ 271

 Score = 36.2 bits (82), Expect = 0.048,   Method: Compositional matrix adjust.
 Identities = 23/77 (29%), Positives = 40/77 (51%)
 Frame = -1

Query: 193 VYIKNFGEEVDDGNLKELFSQFGKTLSVKVMRDXXXXXXXXXXVSYEKHEDANKAVEEMN 252
           VY+   G  V +  LK  FS FG  +++ + R+          V++EK E A++A+  MN
Sbjct: 480 VYVHGIG--VTEDILKSAFSNFGNIVNINIERERNNGF-----VTFEKMESADQAIANMN 322

Query: 253 GKEMSGKAIFVGRAQKK 269
           G  +S   + V  A+++
Sbjct: 321 GSMISNVQLKVMMARRQ 271
>02091
          Length = 2031

 Score = 41.6 bits (96), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 32/77 (41%), Positives = 45/77 (58%), Gaps = 1/77 (1%)
 Frame = -2

Query: 564  VQGQEPLTASMLAAAPPQEQKQMLGERLFPLIQTMHSNLAGKITGMLLEIDNSELLH-ML 622
             QGQ    A+ +A A PQ Q QM+GE+LF L+    S+     T  +L+ DNSELL  ML
Sbjct: 1406 CQGQN--EAATVAEAHPQVQTQMIGEQLFSLM----SDXYPYPTDXMLKFDNSELLRIML 1245

Query: 623  ESPESLRSKVDEAVAVL 639
            E  +S+  + D A+ +L
Sbjct: 1244 ECQQSVNYR-DAAMVML 1197
>00556
          Length = 2189

 Score = 41.2 bits (95), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 47/203 (23%), Positives = 82/203 (40%), Gaps = 29/203 (14%)
 Frame = +3

Query: 13  LYVGDLHSDVTEAMLYEKF-----------SPAGPVLSIRVCRDMI-----------TRR 50
           LYVG++   VTE  + + F           +   PV+++ +  D             T +
Sbjct: 435 LYVGNIPFGVTEESMMDFFNHQMKITGLAQAEGDPVIAVHINLDKNFAFLELRSVDETTQ 614

Query: 51  SLGYAYVNFQ-QPADAERALDTMNFDVMKGKPIRIMWSQRDPSLRKSGVGN----VFIKN 105
           +L +  + ++ QP    R  D      +   P     +Q  P +  + V +    +F+  
Sbjct: 615 ALAFDGIAYETQPLKIRRPSDYKPLPGLSENP-----TQAVPGVVSTVVQDSDHKIFMGG 779

Query: 106 LDKSIDNKALYDTFSAFGNILSCKVVCDENG--SKGYAFVHFETQEAADKAIEKMNGMLL 163
           L   +    + +   +FG + S  +V D     SKG+AF  +      D+A   +NGM L
Sbjct: 780 LPSYLSEDQMKELLLSFGPLKSFNLVRDNATGLSKGFAFCEYLDPSVTDQACAGLNGMQL 959

Query: 164 NDRKVFVGRFKSRKEREAELGAK 186
            D+K+ V R        A +GAK
Sbjct: 960 GDKKLIVQR--------ASIGAK 1004

 Score = 33.5 bits (75), Expect = 0.26,   Method: Compositional matrix adjust.
 Identities = 18/72 (25%), Positives = 36/72 (50%), Gaps = 2/72 (2%)
 Frame = +3

Query: 296 LYIKNLDDTIDDEKLRREFSPFGSITSAKVMLED--GRSKGFGFVCFSSPEEATKAVTEM 353
           +++  L   + +++++     FG + S  ++ ++  G SKGF F  +  P    +A   +
Sbjct: 765 IFMGGLPSYLSEDQMKELLLSFGPLKSFNLVRDNATGLSKGFAFCEYLDPSVTDQACAGL 944

Query: 354 NGRIVGSKPLYV 365
           NG  +G K L V
Sbjct: 945 NGMQLGDKKLIV 980
>20169
          Length = 1364

 Score = 40.8 bits (94), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 22/76 (28%), Positives = 40/76 (52%)
 Frame = -1

Query: 13   LYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDTM 72
            +YVG+L     +  L +KF+  GP+ ++      + RR  G+A+V F+   DAE A+  +
Sbjct: 1064 VYVGELGHGCAKQELEDKFAKYGPLKNV-----WVARRPAGFAFVEFEDNRDAEDAVQAL 900

Query: 73   NFDVMKGKPIRIMWSQ 88
            +   + G+  R+  S 
Sbjct: 899  DGARINGRRARVEMSN 852
>12506
          Length = 1056

 Score = 40.8 bits (94), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 26/91 (28%), Positives = 43/91 (47%), Gaps = 7/91 (7%)
 Frame = -3

Query: 305  IDDEKLRREFSPFGSITSAKVML--EDGRSKGFGFVCFSSPEEATKAVTEMNGRIVGSKP 362
            +DD+ L   F PFG I   ++ L  E  + +GF F+ F   E+A  A+  MN   +  + 
Sbjct: 1030 VDDKVLHAAFLPFGDIVDIQIPLDYETEKHRGFAFIEFELAEDAAAAIDNMNESELFGRT 851

Query: 363  LYVALA-----QRKEERKAHLTNQYMQRVAG 388
            + V LA     +    R     + ++Q+ AG
Sbjct: 850  IRVNLAKPMKVKEGASRAVWADDTWLQQHAG 758
>33516
          Length = 449

 Score = 40.4 bits (93), Expect = 0.002,   Method: Composition-based stats.
 Identities = 20/50 (40%), Positives = 29/50 (58%), Gaps = 2/50 (4%)
 Frame = +1

Query: 296 LYIKNLDDTIDDEKLRREFSPFGSITSAKVML--EDGRSKGFGFVCFSSP 343
           +++  L    D + L+  FS FG IT   VM+  + G+S+GFGFV F  P
Sbjct: 160 IFVGGLSWDTDQDSLQGYFSQFGEITDCIVMMNQQTGKSRGFGFVSFKDP 309
>02809
          Length = 1475

 Score = 39.7 bits (91), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 19/61 (31%), Positives = 34/61 (55%)
 Frame = -1

Query: 13   LYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDTM 72
            +YVG+L     +  L +KF+  GP+ ++      + RR  G+A+V F+   DAE A+  +
Sbjct: 1328 VYVGELGHGCAKQELEDKFAKYGPLKNV-----WVARRPAGFAFVEFEDNRDAEDAVQAL 1164

Query: 73   N 73
            +
Sbjct: 1163 D 1161
>03059
          Length = 1154

 Score = 39.3 bits (90), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 24/71 (33%), Positives = 39/71 (54%), Gaps = 1/71 (1%)
 Frame = -2

Query: 13  LYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMI-TRRSLGYAYVNFQQPADAERALDT 71
           ++VG L  +V +  + E FS  G +  I +  D I    S G+AYV ++ P DAE+A+  
Sbjct: 664 VHVGRLTRNVNKDHIQEIFSLYGTIKFIDLPNDRIHPNTSKGHAYVEYENPEDAEKAVKY 485

Query: 72  MNFDVMKGKPI 82
           M+   + G+ I
Sbjct: 484 MDGGQIDGQEI 452

 Score = 36.6 bits (83), Expect = 0.031,   Method: Compositional matrix adjust.
 Identities = 22/73 (30%), Positives = 37/73 (50%), Gaps = 2/73 (2%)
 Frame = -2

Query: 191 TNVYIKNFGEEVDDGNLKELFSQFG--KTLSVKVMRDXXXXXXXXXXVSYEKHEDANKAV 248
           T V++      V+  +++E+FS +G  K + +   R           V YE  EDA KAV
Sbjct: 670 TKVHVGRLTRNVNKDHIQEIFSLYGTIKFIDLPNDRIHPNTSKGHAYVEYENPEDAEKAV 491

Query: 249 EEMNGKEMSGKAI 261
           + M+G ++ G+ I
Sbjct: 490 KYMDGGQIDGQEI 452

 Score = 33.1 bits (74), Expect = 0.38,   Method: Compositional matrix adjust.
 Identities = 17/65 (26%), Positives = 34/65 (52%), Gaps = 3/65 (4%)
 Frame = -2

Query: 294 VNLYIKNLDDTIDDEKLRREFSPFGSITSAKV---MLEDGRSKGFGFVCFSSPEEATKAV 350
             +++  L   ++ + ++  FS +G+I    +    +    SKG  +V + +PE+A KAV
Sbjct: 670 TKVHVGRLTRNVNKDHIQEIFSLYGTIKFIDLPNDRIHPNTSKGHAYVEYENPEDAEKAV 491

Query: 351 TEMNG 355
             M+G
Sbjct: 490 KYMDG 476
>10194
          Length = 1278

 Score = 38.5 bits (88), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 24/77 (31%), Positives = 37/77 (48%)
 Frame = -3

Query: 12  SLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDT 71
           S++VG+L  D+ E  +   F   G V +IRV RD  T    G  Y+ F+       AL  
Sbjct: 403 SVFVGNLPFDIEEESVRSHFEDCGDVENIRVVRDRKTNLGKGICYILFKSADSVSLALKL 224

Query: 72  MNFDVMKGKPIRIMWSQ 88
            N ++ K + IR+   +
Sbjct: 223 NNSELEK-RQIRVQRCK 176
>32386
          Length = 674

 Score = 38.1 bits (87), Expect = 0.010,   Method: Compositional matrix adjust.
 Identities = 23/72 (31%), Positives = 36/72 (50%), Gaps = 6/72 (8%)
 Frame = +1

Query: 296 LYIKNLDDTIDDEKLRREFSPFGSITSAKVMLEDG--RSKGFGFVCFSSPEEATKAVT-- 351
           L+I  L    D++ LR  F  +G I    VM +    RS+GFGF+ +   E   +A    
Sbjct: 307 LFIGGLSYETDEDSLRSHFETWGEIVDCIVMRDSNSKRSRGFGFITYKDAESIDQAQANR 486

Query: 352 --EMNGRIVGSK 361
             +++GR V +K
Sbjct: 487 PHKIDGREVDTK 522
>03406
          Length = 1292

 Score = 37.7 bits (86), Expect = 0.014,   Method: Compositional matrix adjust.
 Identities = 23/73 (31%), Positives = 34/73 (46%), Gaps = 6/73 (8%)
 Frame = +3

Query: 296 LYIKNLDDTIDDEKLRREFSPFGSITSA--KVMLEDGRSKGFGFVCFSSPEEATKAVT-- 351
           +++  L      + LR  F  FG +TS   K  L+ G+S+GFGFV F         V   
Sbjct: 246 IFVGGLSWETXSKHLREYFEKFGEVTSCTLKTDLDSGKSRGFGFVVFKEAATVDAVVKNK 425

Query: 352 --EMNGRIVGSKP 362
             ++ GR +  KP
Sbjct: 426 EHKLQGRKIDPKP 464
>26197
          Length = 1365

 Score = 37.7 bits (86), Expect = 0.014,   Method: Compositional matrix adjust.
 Identities = 23/73 (31%), Positives = 34/73 (46%), Gaps = 6/73 (8%)
 Frame = -2

Query: 296  LYIKNLDDTIDDEKLRREFSPFGSITSA--KVMLEDGRSKGFGFVCFSSPEEATKAVT-- 351
            +++  L      + LR  F  FG +TS   K  L+ G+S+GFGFV F         V   
Sbjct: 1292 IFVGGLSWETSSKHLREYFEKFGEVTSCTLKTDLDSGKSRGFGFVVFKEAVTVDAVVKNK 1113

Query: 352  --EMNGRIVGSKP 362
              ++ GR +  KP
Sbjct: 1112 EHKLQGRKIDPKP 1074
>31618
          Length = 716

 Score = 37.4 bits (85), Expect = 0.018,   Method: Compositional matrix adjust.
 Identities = 43/155 (27%), Positives = 68/155 (43%), Gaps = 16/155 (10%)
 Frame = +1

Query: 13  LYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNF-------QQPADA 65
           L+VG L  + TE  L + F   G + SI V  D  T RS G+A++ F       Q  A  
Sbjct: 298 LFVGGLSWETTEKELRDHFGKYGEIESINVKTDPQTGRSRGFAFIVFTNTEAIDQVSAAE 477

Query: 66  ERALDTMNFDVMKGKP-------IRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDT 118
           E  +++   D  K KP       + +   QR  ++RKS   +V   NLD           
Sbjct: 478 EHIINSKKVDP-KKKPRLAMARFLSVA*PQR-LAMRKSKPTSV---NLD----------- 609

Query: 119 FSAFGNILSCKVVCDENGS--KGYAFVHFETQEAA 151
                NI+  ++  D+  S  KG+ F+ F++++  
Sbjct: 610 -----NIVEVEMPFDKQKSHRKGFXFITFDSEQVV 699

 Score = 37.0 bits (84), Expect = 0.023,   Method: Compositional matrix adjust.
 Identities = 22/68 (32%), Positives = 35/68 (51%), Gaps = 2/68 (2%)
 Frame = +1

Query: 296 LYIKNLDDTIDDEKLRREFSPFGSITSAKVMLE--DGRSKGFGFVCFSSPEEATKAVTEM 353
           L++  L     +++LR  F  +G I S  V  +   GRS+GF F+ F++  EA   V+  
Sbjct: 298 LFVGGLSWETTEKELRDHFGKYGEIESINVKTDPQTGRSRGFAFIVFTN-TEAIDQVSAA 474

Query: 354 NGRIVGSK 361
              I+ SK
Sbjct: 475 EEHIINSK 498
>02347
          Length = 928

 Score = 37.0 bits (84), Expect = 0.023,   Method: Compositional matrix adjust.
 Identities = 21/75 (28%), Positives = 39/75 (52%)
 Frame = -3

Query: 13  LYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDTM 72
           +YVGDL  D +E  +   F+  G + ++      + R   G+A+V F+   DA+ A+  +
Sbjct: 740 IYVGDLPPDASEKEVERAFNYYGHLRNV-----WVARNPPGFAFVEFEDTRDADDAVRAL 576

Query: 73  NFDVMKGKPIRIMWS 87
           +  V+ G  +R+  S
Sbjct: 575 DGTVVCGNRVRVEHS 531
>05987
          Length = 1726

 Score = 36.2 bits (82), Expect = 0.038,   Method: Compositional matrix adjust.
 Identities = 45/198 (22%), Positives = 86/198 (43%), Gaps = 12/198 (6%)
 Frame = -2

Query: 100  NVFIKNLDKSI---DNKALYDTFSAFGNILSCKVVCDENGSKGYAFVHFETQEAADKAIE 156
             +F+KNL  ++   D K+L          ++ +    +    G+A+V F ++  ADK  +
Sbjct: 1167 TLFVKNLPPTVSVTDIKSLSKDIKEVRLRIAVRAKQRQKKKMGFAYVEFASEALADKNYK 988

Query: 157  KMNGMLLNDRKV---FVGRFKSRKEREAELGAKA-KEFTN-----VYIKNFGEEVDDGNL 207
            ++ G  L D  +   +VG      ++ A L  K  KEF +     +YI  FG E  + +L
Sbjct: 987  QLQGTKLKDWDLVVDYVG------QKSAYLANKPRKEFADPDPLRLYITGFGSETKEADL 826

Query: 208  KELFSQFGKTLSVKVMRDXXXXXXXXXXVSYEKHEDANKAVEEMNGKEMSGKAIFVGRAQ 267
             +LF +  + +  K  +D            +   E    A  +  G ++ G  + V  A+
Sbjct: 825  FKLFPKAQEIVIPKRKKDNKPVGYAFAV--FVTDEQCKTAFHKNQGAKLQGHNLVVLYAK 652

Query: 268  KKVERQAELKRKFEQLKQ 285
            K+  ++ +  ++ EQ  Q
Sbjct: 651  KRTAQKQQKAKESEQKTQ 598
>01065
          Length = 1033

 Score = 36.2 bits (82), Expect = 0.045,   Method: Compositional matrix adjust.
 Identities = 19/70 (27%), Positives = 36/70 (51%)
 Frame = +2

Query: 101 VFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENGSKGYAFVHFETQEAADKAIEKMNG 160
           + + +L  S   + + + F  FG+I+   +          AFV +  +E A+KAI +M+G
Sbjct: 20  IHVGSLSSSTSTREIREEFKRFGDIIDLWM---PRTQPTIAFVVYRYEEDAEKAIRRMDG 190

Query: 161 MLLNDRKVFV 170
             ++ R+V V
Sbjct: 191 ESMHGRRVRV 220
>00738
          Length = 1559

 Score = 35.4 bits (80), Expect = 0.064,   Method: Compositional matrix adjust.
 Identities = 19/70 (27%), Positives = 36/70 (51%)
 Frame = -2

Query: 101  VFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENGSKGYAFVHFETQEAADKAIEKMNG 160
            + + +L  S   + + + F  FG+I+   +          AFV +  +E A+KAI +M+G
Sbjct: 1261 IHVGSLSSSTSTREIREEFKRFGDIIDLWM---PRTQPTIAFVVYRYEEDAEKAIRRMDG 1091

Query: 161  MLLNDRKVFV 170
              ++ R+V V
Sbjct: 1090 ESMHGRRVRV 1061
>32733
          Length = 709

 Score = 35.4 bits (80), Expect = 0.079,   Method: Compositional matrix adjust.
 Identities = 17/42 (40%), Positives = 28/42 (66%), Gaps = 1/42 (2%)
 Frame = +1

Query: 119 FSAFGNILSCKVVCDENG-SKGYAFVHFETQEAADKAIEKMN 159
           F +FG+I  C V+ D NG S+G AF+ F +++ A  +I+ M+
Sbjct: 526 FESFGSIDDCTVLRDSNGTSRGCAFITFASRQCAMNSIKGMH 651
>15503
          Length = 570

 Score = 35.0 bits (79), Expect = 0.094,   Method: Composition-based stats.
 Identities = 22/77 (28%), Positives = 41/77 (53%)
 Frame = +1

Query: 101 VFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENGSKGYAFVHFETQEAADKAIEKMNG 160
           +++KNL   I  + +YD F  +G I   + V +   +KG AFV +E    A  A + ++G
Sbjct: 154 LYVKNLPYKITAEEMYDIFGKYGAIRQIR-VGNTPETKGTAFVVYEDIFDAKNACDHLSG 330

Query: 161 MLLNDRKVFVGRFKSRK 177
             + +R + V  ++S +
Sbjct: 331 FNVCNRYLVVLYYQSTR 381

 Score = 30.8 bits (68), Expect = 1.9,   Method: Composition-based stats.
 Identities = 25/96 (26%), Positives = 44/96 (45%)
 Frame = +1

Query: 296 LYIKNLDDTIDDEKLRREFSPFGSITSAKVMLEDGRSKGFGFVCFSSPEEATKAVTEMNG 355
           LY+KNL   I  E++   F  +G+I   +V      +KG  FV +    +A  A   ++G
Sbjct: 154 LYVKNLPYKITAEEMYDIFGKYGAIRQIRVG-NTPETKGTAFVVYEDIFDAKNACDHLSG 330

Query: 356 RIVGSKPLYVALAQRKEERKAHLTNQYMQRVAGMRA 391
             V ++ L V   Q     K   T++  + +  M++
Sbjct: 331 FNVCNRYLVVLYYQSTRAFKKLDTDKKKEELDKMKS 438

 Score = 30.0 bits (66), Expect = 3.4,   Method: Composition-based stats.
 Identities = 21/83 (25%), Positives = 41/83 (49%)
 Frame = +1

Query: 13  LYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDTM 72
           LYV +L   +T   +Y+ F   G +  IRV     T  + G A+V ++   DA+ A D +
Sbjct: 154 LYVKNLPYKITAEEMYDIFGKYGAIRQIRVGN---TPETKGTAFVVYEDIFDAKNACDHL 324

Query: 73  NFDVMKGKPIRIMWSQRDPSLRK 95
           +   +  + + +++ Q   + +K
Sbjct: 325 SGFNVCNRYLVVLYYQSTRAFKK 393
>08670
          Length = 1307

 Score = 34.7 bits (78), Expect = 0.12,   Method: Compositional matrix adjust.
 Identities = 24/95 (25%), Positives = 47/95 (49%)
 Frame = +2

Query: 10   MASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERAL 69
            + +L+VG++   VTE  L + F+  GPV S+R+  +         A++N++    A RA+
Sbjct: 950  LTALWVGNVLPQVTEKRLTQMFAKHGPVASVRMLPEKYC------AFINYKLKESAGRAM 1111

Query: 70   DTMNFDVMKGKPIRIMWSQRDPSLRKSGVGNVFIK 104
              +     +G+ + I    R P    +  GN+ ++
Sbjct: 1112 QYLQNQECEGQHLLI----RFPDNPINPTGNITLR 1204
>00781
          Length = 3170

 Score = 34.3 bits (77), Expect = 0.15,   Method: Compositional matrix adjust.
 Identities = 22/61 (36%), Positives = 32/61 (52%), Gaps = 2/61 (3%)
 Frame = -1

Query: 296  LYIKNLDDTIDDEKLRREFSPFGSITSAKV-MLEDGRS-KGFGFVCFSSPEEATKAVTEM 353
            +Y++        E + R FS  G++T   +   +  R  KG+ FV F SPEEA KAV  +
Sbjct: 2714 VYVEGFHKFTSREWISRMFSKCGTVTYVSLPCFKTTREIKGYAFVEFQSPEEAVKAVQML 2535

Query: 354  N 354
            N
Sbjct: 2534 N 2532

 Score = 32.7 bits (73), Expect = 0.52,   Method: Compositional matrix adjust.
 Identities = 23/81 (28%), Positives = 39/81 (48%), Gaps = 2/81 (2%)
 Frame = -1

Query: 81   PIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENGS--K 138
            PIR + +Q +   R      V+++   K    + +   FS  G +    + C +     K
Sbjct: 2756 PIRFL-TQEETDAR-----TVYVEGFHKFTSREWISRMFSKCGTVTYVSLPCFKTTREIK 2595

Query: 139  GYAFVHFETQEAADKAIEKMN 159
            GYAFV F++ E A KA++ +N
Sbjct: 2594 GYAFVEFQSPEEAVKAVQMLN 2532
>23322
          Length = 471

 Score = 33.9 bits (76), Expect = 0.20,   Method: Composition-based stats.
 Identities = 25/92 (27%), Positives = 45/92 (48%), Gaps = 7/92 (7%)
 Frame = -2

Query: 277 KRKFEQLKQERISRYQGVN-LYIKNLDDTIDDEKLRREFSPFGSITSAKVMLEDG--RSK 333
           KR   + +  R    Q V  +++  + +   ++ +R  F+ FG IT   ++ + G  +++
Sbjct: 464 KRAMPREESGRSEVQQSVKKMFVGGVKEDTTEDMIRDTFNEFGEITGVDLIQDKGTGKNR 285

Query: 334 GFGFVCFSSPEEATKAVT----EMNGRIVGSK 361
           GF FV F   +   KAV     ++NGR V  K
Sbjct: 284 GFCFVTFGDHDSVDKAVLKKRHDLNGRQVEVK 189
>25950
          Length = 417

 Score = 33.9 bits (76), Expect = 0.22,   Method: Compositional matrix adjust.
 Identities = 19/73 (26%), Positives = 37/73 (50%), Gaps = 2/73 (2%)
 Frame = -2

Query: 100 NVFIKNLDKSIDNKALYDTFSAFGNILSCKVVCD--ENGSKGYAFVHFETQEAADKAIEK 157
           +V++ N+D     + L   F   G I    ++C+  +   KG+A++ F ++E  + A+  
Sbjct: 278 SVYVGNVDYGASAEELEAHFHGCGTINRVTILCNKADGHPKGFAYIEFGSKEYVETAL-A 102

Query: 158 MNGMLLNDRKVFV 170
           MN  L   R++ V
Sbjct: 101 MNETLFRGRQIKV 63

 Score = 33.1 bits (74), Expect = 0.33,   Method: Compositional matrix adjust.
 Identities = 19/74 (25%), Positives = 34/74 (45%)
 Frame = -2

Query: 12  SLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDT 71
           S+YVG++    +   L   F   G +  + +  +       G+AY+ F      E AL  
Sbjct: 278 SVYVGNVDYGASAEELEAHFHGCGTINRVTILCNKADGHPKGFAYIEFGSKEYVETAL-A 102

Query: 72  MNFDVMKGKPIRIM 85
           MN  + +G+ I++M
Sbjct: 101 MNETLFRGRQIKVM 60
>29364
          Length = 1126

 Score = 33.9 bits (76), Expect = 0.24,   Method: Compositional matrix adjust.
 Identities = 18/62 (29%), Positives = 32/62 (51%)
 Frame = +1

Query: 202 VDDGNLKELFSQFGKTLSVKVMRDXXXXXXXXXXVSYEKHEDANKAVEEMNGKEMSGKAI 261
           V + +L+  F  +G+T  + +             V +E + DA+ AV E+NGKE+ G+ +
Sbjct: 1   VRERDLERFFKGYGRTRDILI-------KNGYGFVEFEDYRDADDAVYELNGKELLGERV 159

Query: 262 FV 263
            V
Sbjct: 160 VV 165

 Score = 29.6 bits (65), Expect = 3.6,   Method: Compositional matrix adjust.
 Identities = 14/32 (43%), Positives = 18/32 (56%)
 Frame = +1

Query: 139 GYAFVHFETQEAADKAIEKMNGMLLNDRKVFV 170
           GY FV FE    AD A+ ++NG  L   +V V
Sbjct: 70  GYGFVEFEDYRDADDAVYELNGKELLGERVVV 165
>04988
          Length = 705

 Score = 33.9 bits (76), Expect = 0.24,   Method: Compositional matrix adjust.
 Identities = 22/82 (26%), Positives = 41/82 (50%)
 Frame = -3

Query: 288 ISRYQGVNLYIKNLDDTIDDEKLRREFSPFGSITSAKVMLEDGRSKGFGFVCFSSPEEAT 347
           +S   G  +YI  L     ++ + R F  +G +    +ML++G    +GFV F    +A 
Sbjct: 670 LSNRMGTRVYIGRLPYQAREKDIERFFRGYGRVND--IMLKNG----YGFVEFEDFRDAD 509

Query: 348 KAVTEMNGRIVGSKPLYVALAQ 369
            AV E+NG+ +  + + +  A+
Sbjct: 508 DAVYELNGKDLCGERVIIEHAR 443

 Score = 32.3 bits (72), Expect = 0.56,   Method: Compositional matrix adjust.
 Identities = 18/77 (23%), Positives = 36/77 (46%)
 Frame = -3

Query: 191 TNVYIKNFGEEVDDGNLKELFSQFGKTLSVKVMRDXXXXXXXXXXVSYEKHEDANKAVEE 250
           T VYI     +  + +++  F  +G+   + +             V +E   DA+ AV E
Sbjct: 652 TRVYIGRLPYQAREKDIERFFRGYGRVNDIML-------KNGYGFVEFEDFRDADDAVYE 494

Query: 251 MNGKEMSGKAIFVGRAQ 267
           +NGK++ G+ + +  A+
Sbjct: 493 LNGKDLCGERVIIEHAR 443

 Score = 29.3 bits (64), Expect = 5.7,   Method: Compositional matrix adjust.
 Identities = 13/32 (40%), Positives = 18/32 (56%)
 Frame = -3

Query: 139 GYAFVHFETQEAADKAIEKMNGMLLNDRKVFV 170
           GY FV FE    AD A+ ++NG  L   +V +
Sbjct: 550 GYGFVEFEDFRDADDAVYELNGKDLCGERVII 455
>11019
          Length = 552

 Score = 33.9 bits (76), Expect = 0.24,   Method: Composition-based stats.
 Identities = 17/38 (44%), Positives = 21/38 (55%), Gaps = 2/38 (5%)
 Frame = -1

Query: 308 EKLRREFSPFGSITSAKVMLE--DGRSKGFGFVCFSSP 343
           E LR  F  FG I  + VM +    RS+GFGFV +  P
Sbjct: 522 ETLRSYFEKFGEIKESMVMKDPTSKRSRGFGFVTYKDP 409
>12350
          Length = 975

 Score = 33.5 bits (75), Expect = 0.25,   Method: Compositional matrix adjust.
 Identities = 23/73 (31%), Positives = 38/73 (52%), Gaps = 5/73 (6%)
 Frame = -2

Query: 289 SRYQGVNLYIKNLDDTIDDEKLRREFSPFGSITSAKVMLE--DGRSKGFGFVCFSSPEEA 346
           SR +  +L +  L     ++ LR  FS FG +   +V  +   G+SKGFGF+ F+  E  
Sbjct: 635 SRQKCSDLIVLGLPWKSTEDDLRSYFSQFGDLLMVQVKKDPKTGQSKGFGFIRFAEYESQ 456

Query: 347 TKAVTE---MNGR 356
            K + +   ++GR
Sbjct: 455 LKCMAQRHMIDGR 417
>23720
          Length = 739

 Score = 33.5 bits (75), Expect = 0.27,   Method: Compositional matrix adjust.
 Identities = 22/82 (26%), Positives = 41/82 (50%)
 Frame = -1

Query: 288 ISRYQGVNLYIKNLDDTIDDEKLRREFSPFGSITSAKVMLEDGRSKGFGFVCFSSPEEAT 347
           +S   G  +YI  L     ++ + R F  +G +    +ML++G    +GFV F    +A 
Sbjct: 703 LSNRMGTRVYIGRLPYQAREKDIERFFRGYGRVND--IMLKNG----YGFVEFEDFRDAD 542

Query: 348 KAVTEMNGRIVGSKPLYVALAQ 369
            AV E+NG+ +  + + +  A+
Sbjct: 541 DAVYELNGKDLCGERVIIEHAR 476

 Score = 32.0 bits (71), Expect = 0.77,   Method: Compositional matrix adjust.
 Identities = 18/77 (23%), Positives = 36/77 (46%)
 Frame = -1

Query: 191 TNVYIKNFGEEVDDGNLKELFSQFGKTLSVKVMRDXXXXXXXXXXVSYEKHEDANKAVEE 250
           T VYI     +  + +++  F  +G+   + +             V +E   DA+ AV E
Sbjct: 685 TRVYIGRLPYQAREKDIERFFRGYGRVNDIML-------KNGYGFVEFEDFRDADDAVYE 527

Query: 251 MNGKEMSGKAIFVGRAQ 267
           +NGK++ G+ + +  A+
Sbjct: 526 LNGKDLCGERVIIEHAR 476

 Score = 29.3 bits (64), Expect = 5.7,   Method: Compositional matrix adjust.
 Identities = 13/32 (40%), Positives = 18/32 (56%)
 Frame = -1

Query: 139 GYAFVHFETQEAADKAIEKMNGMLLNDRKVFV 170
           GY FV FE    AD A+ ++NG  L   +V +
Sbjct: 583 GYGFVEFEDFRDADDAVYELNGKDLCGERVII 488
>11126
          Length = 1061

 Score = 33.5 bits (75), Expect = 0.31,   Method: Compositional matrix adjust.
 Identities = 30/122 (24%), Positives = 50/122 (40%), Gaps = 13/122 (10%)
 Frame = -3

Query: 241 HEDANKAVEEMNG-----KEMSGKAIFVGRAQKKVERQAELKRKFEQL------KQERIS 289
           HED+N    E+       +EM  +A  +   Q +VE+Q  L              QE   
Sbjct: 822 HEDSNVEDPELEAIKARVREMEAEAEKLKEMQSEVEKQMNLSSPTSAATASPFPSQEDKI 643

Query: 290 RYQGVNLYIKNLDDTIDDEKLRREFSPFGSITSAKVMLE--DGRSKGFGFVCFSSPEEAT 347
                ++Y+ N+D     E+L + F   GS+    ++ +   G  KGF +V F+  +   
Sbjct: 642 EADLRSVYVGNVDYGATAEELEQHFHGCGSVNRVTILCDKYSGHPKGFAYVEFADKDSVV 463

Query: 348 KA 349
            A
Sbjct: 462 TA 457

 Score = 31.6 bits (70), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 23/91 (25%), Positives = 38/91 (41%), Gaps = 9/91 (9%)
 Frame = -3

Query: 3   AAASSYP---------MASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLG 53
           A AS +P         + S+YVG++    T   L + F   G V  + +  D  +    G
Sbjct: 681 ATASPFPSQEDKIEADLRSVYVGNVDYGATAEELEQHFHGCGSVNRVTILCDKYSGHPKG 502

Query: 54  YAYVNFQQPADAERALDTMNFDVMKGKPIRI 84
           +AYV F        A  T    + +G+ I++
Sbjct: 501 FAYVEFADKDSVVTAKCTGMDSLFRGRQIKV 409

 Score = 30.0 bits (66), Expect = 3.2,   Method: Compositional matrix adjust.
 Identities = 20/75 (26%), Positives = 37/75 (49%), Gaps = 4/75 (5%)
 Frame = -3

Query: 100 NVFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENGS--KGYAFVHFETQEAADKAIEK 157
           +V++ N+D     + L   F   G++    ++CD+     KG+A+V F  +++   A  K
Sbjct: 627 SVYVGNVDYGATAEELEQHFHGCGSVNRVTILCDKYSGHPKGFAYVEFADKDSVVTA--K 454

Query: 158 MNGM--LLNDRKVFV 170
             GM  L   R++ V
Sbjct: 453 CTGMDSLFRGRQIKV 409
>31265
          Length = 540

 Score = 33.1 bits (74), Expect = 0.34,   Method: Compositional matrix adjust.
 Identities = 36/127 (28%), Positives = 59/127 (46%), Gaps = 9/127 (7%)
 Frame = +2

Query: 53  GYAYVNF---QQPADAERALDTMNFDVMKGKPIRIMWSQRDPSLRKSGVGNVFI---KNL 106
           G+A+V +   +  A A R L      +  G  I + W++ +  + +  +  V I   +NL
Sbjct: 5   GFAFVEYTSHRAAAMARRKLIPGRIQLW-GHQIAVDWAEPEQDVDEDTMSQVKILXVRNL 181

Query: 107 DKSIDNKALYDTFS-AFG--NILSCKVVCDENGSKGYAFVHFETQEAADKAIEKMNGMLL 163
             +   + L D FS A G   I   K + D      YAFVHF ++E A KA++  +G  +
Sbjct: 182 MLTTTEETLKDVFSRAAGGREIERVKKIRD------YAFVHFRSREDAIKAMDVTDGSTI 343

Query: 164 NDRKVFV 170
              +V V
Sbjct: 344 EGSQVEV 364
>03097
          Length = 1401

 Score = 32.3 bits (72), Expect = 0.66,   Method: Compositional matrix adjust.
 Identities = 19/61 (31%), Positives = 29/61 (47%), Gaps = 7/61 (11%)
 Frame = +1

Query: 131 VCDENGSK--GYAFVHFETQEAADKAIEKMNGMLLNDRKVF-----VGRFKSRKEREAEL 183
           +CD  G    G  +V F  +E ADKA+  +N    N R ++     V  F+    R+ E+
Sbjct: 211 ICDNLGDHLVGNVYVKFRKEEDADKAVADLNNRWFNGRPIYAELTPVTDFREACCRQYEM 390

Query: 184 G 184
           G
Sbjct: 391 G 393

 Score = 31.2 bits (69), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 17/68 (25%), Positives = 33/68 (48%)
 Frame = +1

Query: 195 IKNFGEEVDDGNLKELFSQFGKTLSVKVMRDXXXXXXXXXXVSYEKHEDANKAVEEMNGK 254
             +F EE+      EL  ++G+   + +  +          V + K EDA+KAV ++N +
Sbjct: 142 FDDFFEEI----FIELAEKYGEIEEMNICDNLGDHLVGNVYVKFRKEEDADKAVADLNNR 309

Query: 255 EMSGKAIF 262
             +G+ I+
Sbjct: 310 WFNGRPIY 333

 Score = 30.8 bits (68), Expect = 1.9,   Method: Compositional matrix adjust.
 Identities = 14/40 (35%), Positives = 22/40 (55%)
 Frame = +1

Query: 337 FVCFSSPEEATKAVTEMNGRIVGSKPLYVALAQRKEERKA 376
           +V F   E+A KAV ++N R    +P+Y  L    + R+A
Sbjct: 250 YVKFRKEEDADKAVADLNNRWFNGRPIYAELTPVTDFREA 369
>39789
          Length = 361

 Score = 32.0 bits (71), Expect = 0.71,   Method: Compositional matrix adjust.
 Identities = 22/68 (32%), Positives = 35/68 (51%), Gaps = 5/68 (7%)
 Frame = +1

Query: 296 LYIKNLDDTIDDEKLRREFSPFGSITSAKVMLEDG-RSKGFGFVCFSSPEEATKAVT--- 351
           L++ NL    D   L+  F   G+  +     +D  + +GFGFV FS+P++A  A     
Sbjct: 94  LFVGNLSYDTDQYSLKDAFP--GATAARIAKFQDTQKPRGFGFVEFSTPDDAASAFDSGE 267

Query: 352 -EMNGRIV 358
            E++GR V
Sbjct: 268 REVDGRQV 291
>19980
          Length = 450

 Score = 31.6 bits (70), Expect = 0.98,   Method: Composition-based stats.
 Identities = 19/47 (40%), Positives = 26/47 (55%), Gaps = 1/47 (2%)
 Frame = -2

Query: 304 TIDDEKLRREFSPFGSITSAKVM-LEDGRSKGFGFVCFSSPEEATKA 349
           T +++ LR  FS  G+IT   +    DG+ + F FV FS  EEA  A
Sbjct: 155 TTNEKMLRDLFSKKGTITDCSLKHTADGKFRRFAFVGFSCEEEAKTA 15
>11579
          Length = 1307

 Score = 31.6 bits (70), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 13/38 (34%), Positives = 24/38 (63%)
 Frame = +3

Query: 51 SLGYAYVNFQQPADAERALDTMNFDVMKGKPIRIMWSQ 88
          S G+A+V F    DAE A+D+M+  ++ G+ +R   ++
Sbjct: 3  SRGFAFVRFYDRRDAEDAMDSMDGALLDGREVRCQMAR 116
>25632
          Length = 864

 Score = 31.2 bits (69), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 14/43 (32%), Positives = 19/43 (44%)
 Frame = -2

Query: 118 TFSAFGNILSCKVVCDENGSKGYAFVHFETQEAADKAIEKMNG 160
               +G +  C V+      K Y FVH  T+  A  AI  +NG
Sbjct: 710 CLEKYGTVEECDVL------KNYGFVHMPTKSEASAAITNLNG 600

 Score = 30.0 bits (66), Expect = 2.8,   Method: Compositional matrix adjust.
 Identities = 15/55 (27%), Positives = 28/55 (50%)
 Frame = -2

Query: 317 FGSITSAKVMLEDGRSKGFGFVCFSSPEEATKAVTEMNGRIVGSKPLYVALAQRK 371
           +G++    V+      K +GFV   +  EA+ A+T +NG  +  + + V L+  K
Sbjct: 698 YGTVEECDVL------KNYGFVHMPTKSEASAAITNLNGYNIKGQRMRVELSTNK 552
>28372
          Length = 398

 Score = 31.2 bits (69), Expect = 1.4,   Method: Compositional matrix adjust.
 Identities = 14/33 (42%), Positives = 21/33 (63%)
 Frame = -2

Query: 333 KGFGFVCFSSPEEATKAVTEMNGRIVGSKPLYV 365
           +GFGFV F+   EA +A  +MNG +V  + + V
Sbjct: 259 QGFGFVTFAHSAEAERARDKMNGTVVEGRKIEV 161

 Score = 29.6 bits (65), Expect = 4.2,   Method: Compositional matrix adjust.
 Identities = 12/31 (38%), Positives = 20/31 (64%)
 Frame = -2

Query: 138 KGYAFVHFETQEAADKAIEKMNGMLLNDRKV 168
           +G+ FV F     A++A +KMNG ++  RK+
Sbjct: 259 QGFGFVTFAHSAEAERARDKMNGTVVEGRKI 167
>19733
          Length = 723

 Score = 30.8 bits (68), Expect = 1.7,   Method: Compositional matrix adjust.
 Identities = 20/56 (35%), Positives = 27/56 (48%), Gaps = 9/56 (16%)
 Frame = +3

Query: 36  PVLSIRVCRDMI------TRRSLGYAYVNFQQPADAERALDTMNFDVMKG---KPI 82
            +   RV RD+         +SLGYA+VNF     A +AL  +N   M G   +PI
Sbjct: 480 KITECRVMRDLARTKQSGQSKSLGYAFVNFSTHEHALKALRGLNNSTMFGDSRRPI 647

 Score = 30.8 bits (68), Expect = 1.7,   Method: Compositional matrix adjust.
 Identities = 55/259 (21%), Positives = 103/259 (39%), Gaps = 27/259 (10%)
 Frame = +3

Query: 123 GNILSCKVVCDE--NGSKGYAFVHFETQEAADKAIEKMN------GMLLNDRKVF----V 170
           G +   ++V D+    S+G AFV F+ ++AAD+ +          G+ +  R ++    V
Sbjct: 3   GELAYVRLVIDKVTGQSRGTAFVQFKEKDAADQCLANXQDTTRGGGLRVQGRPLYVVAAV 182

Query: 171 GRFKSRKEREAELGAKAKEFTNVYIKNFGEEVDDGNLKELFSQFGKTLSVKVMRDXXXXX 230
            R +++ ++EA+   + K+  N+++   G       L    +Q  + +S           
Sbjct: 183 SRTQAQTQKEADKSKEQKDNRNLFLAREG-------LIRAGTQAAEGMS----------- 308

Query: 231 XXXXXVSYEKHEDANK--AVEEMNGKEMSGKAIFVGRAQKKVERQAELKRKFEQLKQERI 288
                      ED NK   VE +  +++    IFV                         
Sbjct: 309 ----------QEDINKRMKVEMVKREKLKNINIFVS------------------------ 386

Query: 289 SRYQGVNLYIKNLDDTIDDEKLR---REFSPFGS--ITSAKVMLEDGRSK--------GF 335
                  L + NL  ++D+++L+   R+     +  IT  +VM +  R+K        G+
Sbjct: 387 ----STRLCVHNLLPSVDEKQLKTVVRKIVDDSTMKITECRVMRDLARTKQSGQSKSLGY 554

Query: 336 GFVCFSSPEEATKAVTEMN 354
            FV FS+ E A KA+  +N
Sbjct: 555 AFVNFSTHEHALKALRGLN 611
>29083
          Length = 710

 Score = 30.0 bits (66), Expect = 3.0,   Method: Compositional matrix adjust.
 Identities = 18/59 (30%), Positives = 30/59 (50%), Gaps = 1/59 (1%)
 Frame = -2

Query: 119 FSAFGNILSCKVVCDENGSKG-YAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSR 176
           F A   +   K +  E   KG Y  V + ++  ADKA+ + NG+L++   + V R + R
Sbjct: 691 FQAVYPVRRTKGIFAETTIKGKYGVVKYLSEPDADKAVSESNGLLMDGVPLLVRRMERR 515
>00741
          Length = 1846

 Score = 30.0 bits (66), Expect = 3.0,   Method: Compositional matrix adjust.
 Identities = 14/27 (51%), Positives = 17/27 (62%)
 Frame = -3

Query: 337  FVCFSSPEEATKAVTEMNGRIVGSKPL 363
            FV FS  EE  KAV+ +NGR  G + L
Sbjct: 1430 FVEFSKQEELEKAVSSLNGRFFGGRVL 1350
>30934
          Length = 809

 Score = 30.0 bits (66), Expect = 3.1,   Method: Compositional matrix adjust.
 Identities = 50/202 (24%), Positives = 86/202 (42%), Gaps = 16/202 (7%)
 Frame = +1

Query: 35  GPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDTMNFDVMKGKPIRIM----WSQRD 90
           GPV  + +  D IT++  G+A+V F  P  A +A   ++    +G+ + I+     +Q+ 
Sbjct: 28  GPVTDLDLPVDPITKKIKGFAHVTFMFPEHAVKARMELDRQGFRGRMLHILPGKDRTQKY 207

Query: 91  PSLRKSG---VGNVFIKNLDKSIDN-KALYDTFSAFGNILSCKVVCDEN--------GSK 138
            S  KS    + +   K L KS  N   L+ +  A    ++ K   D++        GS 
Sbjct: 208 VSHEKSSYKKLKDEKTKALVKSSHNWNTLFLSGDAVATAMATKYXADKSDILDDSGKGSL 387

Query: 139 GYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKEREAELGAKAKEFTNVYIKNF 198
           G      ETQ      + +     L D  V +  F      +A+ GA++K  T +  K+ 
Sbjct: 388 GVRMALGETQ------LVQETRQFLIDNGVALDSFS-----QAD-GARSK--TVIIAKDL 525

Query: 199 GEEVDDGNLKELFSQFGKTLSV 220
               +   L E+FS++G    V
Sbjct: 526 PAATESDXLTEVFSKYGTVARV 591
>35379
          Length = 534

 Score = 29.6 bits (65), Expect = 3.6,   Method: Composition-based stats.
 Identities = 21/61 (34%), Positives = 31/61 (50%), Gaps = 2/61 (3%)
 Frame = +1

Query: 314 FSPFGSITSAKV-MLEDGRSKGFGFVCFSSPEEATKAV-TEMNGRIVGSKPLYVALAQRK 371
           FS FG +  AK    E    KG+GFV F + E+A + +  E +  I   + L +  A RK
Sbjct: 46  FSAFGPVKDAK**QTELECPKGYGFVTFENQEDADRIIKKEADNLIFKDRKLNIGPAVRK 225

Query: 372 E 372
           +
Sbjct: 226 Q 228
>12096
          Length = 1585

 Score = 29.6 bits (65), Expect = 3.8,   Method: Compositional matrix adjust.
 Identities = 13/29 (44%), Positives = 18/29 (62%)
 Frame = -3

Query: 330  GRSKGFGFVCFSSPEEATKAVTEMNGRIV 358
            G S+GFGFV F S  EA + +    G++V
Sbjct: 1109 GASRGFGFVEFQSQSEAQRWMDHNQGQVV 1023
>33791
          Length = 247

 Score = 29.3 bits (64), Expect = 4.7,   Method: Composition-based stats.
 Identities = 17/59 (28%), Positives = 28/59 (47%), Gaps = 8/59 (13%)
 Frame = +3

Query: 308 EKLRREFSPFGSITSA--------KVMLEDGRSKGFGFVCFSSPEEATKAVTEMNGRIV 358
           +  RR   PF  +T+         +V +    ++GFGFV  SS  ++   + E  GRI+
Sbjct: 63  DPFRRRLHPFPDVTATSQGTAYPYEVTVTRRETEGFGFVIISSVTKSGSTLGEFIGRII 239
>23250
          Length = 1617

 Score = 29.3 bits (64), Expect = 5.7,   Method: Compositional matrix adjust.
 Identities = 18/57 (31%), Positives = 28/57 (49%), Gaps = 2/57 (3%)
 Frame = -1

Query: 94   RKSGVGNVFIKNLDKSIDNKALYDTFSAFGNILSCKVV--CDENGSKGYAFVHFETQ 148
            RKS  G V++ ++        +   FS FG +   ++       GSKGYAF+ F T+
Sbjct: 1350 RKSDRGVVYLGHIPAGFYEPQMKRFFSQFGRVTRLRLSRSTKTGGSKGYAFLEF*TR 1180
>01937
          Length = 1320

 Score = 28.9 bits (63), Expect = 6.8,   Method: Compositional matrix adjust.
 Identities = 21/85 (24%), Positives = 36/85 (42%)
 Frame = -1

Query: 11   ASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALD 70
            + ++VG L S  T       F   G +    +  D +T R  G+A+V F    D E  +D
Sbjct: 1215 SKIFVGGLSSSTTVEDXKNYFKAYGTIEEATLMFDKVTSRHRGFAFVTF----DNESTVD 1048

Query: 71   TMNFDVMKGKPIRIMWSQRDPSLRK 95
             +  + +    ++  W  R  S +K
Sbjct: 1047 KVCENPLP*NQLKKWWRPRKLSPKK 973
>19556
          Length = 917

 Score = 28.9 bits (63), Expect = 6.8,   Method: Compositional matrix adjust.
 Identities = 25/99 (25%), Positives = 44/99 (44%), Gaps = 3/99 (3%)
 Frame = -1

Query: 14  YVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADA-ERALDTM 72
           ++G L   VTE  L EKFS  G V ++ +        S  +AYVN     +  ++     
Sbjct: 821 FIGGLVKGVTEEELMEKFSRFGQVSNVDIKTRTNGIDSRTFAYVNLTAEENGFKKCFTAY 642

Query: 73  NFDVMKGKPIRIMWSQRD--PSLRKSGVGNVFIKNLDKS 109
           N    KG  +++ +++      L+K       +K+ +KS
Sbjct: 641 NNTKWKGGQLKLQYAKESSLSKLKKEQTEARLVKDKEKS 525
>12593
          Length = 462

 Score = 28.9 bits (63), Expect = 7.8,   Method: Compositional matrix adjust.
 Identities = 13/35 (37%), Positives = 22/35 (62%)
 Frame = +2

Query: 134 ENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKV 168
           + GSKG+A+V FE  ++  +A+   NG L  D+ +
Sbjct: 113 QTGSKGFAYVEFEDPDSLQEAL-TYNGALFEDKNL 214
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|45476573|ref|NP_032414.1| eukaryotic translation
initiation factor 3, subunit 6 [Mus musculus]
         (445 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

03597                                                                 572   e-163
07841                                                                 279   2e-75
01018                                                                 124   5e-29
>03597
          Length = 1439

 Score =  572 bits (1474), Expect = e-163,   Method: Compositional matrix adjust.
 Identities = 271/361 (75%), Positives = 313/361 (86%)
 Frame = -3

Query: 73   KRTTVVAQLKQLQAETEPIVKMFEDPETTRQMQSTRDGRMLFDYLADKHGFRQEYLDTLY 132
            KR   V +LK LQAET+ I K+FE+ E  RQ+QS+RDGR LFD+L  ++GF+Q+ LDTLY
Sbjct: 1374 KREEWVGKLKSLQAETDIITKIFEETEVQRQIQSSRDGRQLFDFLYKEYGFKQQMLDTLY 1195

Query: 133  RYAKFQYECGNYSGAAEYLYFFRVLVPATDRNALSSLWGKLASEILMQNWDAAMEDLTRL 192
            +YAKFQYECGNYSG AEYLYF RVL+P +D N +++ WGKLASEILMQ+WD A+EDL ++
Sbjct: 1194 KYAKFQYECGNYSGTAEYLYFVRVLLPPSDPNYMNACWGKLASEILMQSWDVALEDLKKV 1015

Query: 193  KETIDNNSVSSPLQSLQQRTWLIHWSLFVFFNHPKGRDNIIDLFLYQPQYLNAIQTMCPH 252
            +E ID N   + L  LQQRTWLIHWSLFVFFNH KGRD IID FLYQP YLNAIQTMCPH
Sbjct: 1014 QEIIDANQFPNALIGLQQRTWLIHWSLFVFFNHAKGRDLIIDQFLYQPLYLNAIQTMCPH 835

Query: 253  ILRYLTTAVITNKDVRKRRQVLKDLVKVIQQESYTYKDPITEFVECLYVNFDFDGAQKKL 312
            ILRYLTTAVITNK   +R++VLKDLVKVIQQESYTYKDPITEFV CLYV FDF+GAQ+KL
Sbjct: 834  ILRYLTTAVITNKG--RRQKVLKDLVKVIQQESYTYKDPITEFVMCLYVKFDFNGAQQKL 661

Query: 313  RECESVLVNDFFLVACLEDFIENARLFIFETFCRIHQCISINMLADKLNMTPEEAERWIV 372
            RECE VL+NDFFLVACLEDFIENARL IFETFCRIH+CISI MLA+KLNMTP++AERWIV
Sbjct: 660  RECEVVLMNDFFLVACLEDFIENARLLIFETFCRIHECISITMLAEKLNMTPDDAERWIV 481

Query: 373  NLIRNARLDAKIDSKLGHVVMGNNAVSPYQQVIEKTKSLSFRSQMLAMNIEKKLNQNSRS 432
            NLIRNARLDAKIDSKLGHVVMG  AVSPYQQVIEKTK+L+FRSQ+LA+ IEKK + +++ 
Sbjct: 480  NLIRNARLDAKIDSKLGHVVMGTQAVSPYQQVIEKTKNLAFRSQVLALTIEKKTSGHNKQ 301

Query: 433  E 433
            +
Sbjct: 300  D 298
>07841
          Length = 643

 Score =  279 bits (713), Expect = 2e-75,   Method: Compositional matrix adjust.
 Identities = 133/206 (64%), Positives = 167/206 (81%), Gaps = 1/206 (0%)
 Frame = -1

Query: 1   MAEYDLTTRIAHFLDRHLVFPLLEFLSVKEIYNEKELLQGKLDLLSDTNMVDFAMDVYKN 60
           M +YDLT  +  +LDRHLVFPLLEFLSVKE+Y+E ++L+GKL+LLS+TNMVDFAMDV+KN
Sbjct: 622 MEKYDLTPILCQYLDRHLVFPLLEFLSVKELYDENDMLKGKLNLLSNTNMVDFAMDVHKN 443

Query: 61  LYSDDI-PHALREKRTTVVAQLKQLQAETEPIVKMFEDPETTRQMQSTRDGRMLFDYLAD 119
           LY D   P  LREKR  VV +LK LQAET+ I K+FE+ E  RQ+QS+RDGR LFD+L  
Sbjct: 442 LYPDQRDPANLREKRQEVVGKLKSLQAETDIITKIFEETEVQRQIQSSRDGRQLFDFLYK 263

Query: 120 KHGFRQEYLDTLYRYAKFQYECGNYSGAAEYLYFFRVLVPATDRNALSSLWGKLASEILM 179
           ++GF+Q+ LDTLY+YAKFQYECGNYSG AEYLYF RVL+P +D N +++ WGKLASEILM
Sbjct: 262 EYGFKQQMLDTLYKYAKFQYECGNYSGTAEYLYFVRVLLPPSDPNYMNACWGKLASEILM 83

Query: 180 QNWDAAMEDLTRLKETIDNNSVSSPL 205
           Q+WD A+EDL +++E ID N   + L
Sbjct: 82  QSWDVALEDLKKVQEIIDANQFPNAL 5
>01018
          Length = 806

 Score =  124 bits (312), Expect = 5e-29,   Method: Compositional matrix adjust.
 Identities = 58/75 (77%), Positives = 69/75 (92%)
 Frame = +2

Query: 359 KLNMTPEEAERWIVNLIRNARLDAKIDSKLGHVVMGNNAVSPYQQVIEKTKSLSFRSQML 418
           KLNMTP++AERWIVNLIRNARLDAKIDSKLGHVVMG  AVSPYQQVIEKTK+L+FRSQ+L
Sbjct: 227 KLNMTPDDAERWIVNLIRNARLDAKIDSKLGHVVMGTQAVSPYQQVIEKTKNLAFRSQVL 406

Query: 419 AMNIEKKLNQNSRSE 433
           A+ IEKK + +++ +
Sbjct: 407 ALTIEKKTSGHNKQD 451
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|67906177|ref|NP_033173.2| SEC23A [Mus musculus]
         (765 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

11155                                                                 572   e-163
04719                                                                  30   4.1  
>11155
          Length = 1328

 Score =  572 bits (1473), Expect = e-163,   Method: Compositional matrix adjust.
 Identities = 261/323 (80%), Positives = 295/323 (91%)
 Frame = +2

Query: 443 TCQWKICGLSPTTTLAIYFEVVNQHNAPIPQGGRGAVQFVTQYQHSSGQRRIRVTTIARN 502
           TCQWK+CGL P T+L ++FEVVNQHNAPIPQGGRG +QF+TQYQHSSGQRR+RVTT+ARN
Sbjct: 2   TCQWKMCGLYPNTSLGVFFEVVNQHNAPIPQGGRGYLQFITQYQHSSGQRRVRVTTVARN 181

Query: 503 WADAQTQIQNIAASFDQEAAAILMARLAIYRAETEEGPDVLRWLDRQLIRLCQKFGEYHK 562
           WADA T IQ+I+A FDQEA+A+LM R+A+YRAET++GPDVLRWLDR LIRLCQKFGEYHK
Sbjct: 182 WADASTNIQHISAGFDQEASAVLMGRIAVYRAETDDGPDVLRWLDRMLIRLCQKFGEYHK 361

Query: 563 DDPNSFRFSETFSLYPQFMFHLRRSPFLQVFNNSPDESSYYRHHFMRQDLTQSLIMIQPI 622
           DDPNSFRFSE FSLYPQFMFHLRRS FLQVFNNSPDE+SYYRH    +DLTQSLIMIQPI
Sbjct: 362 DDPNSFRFSENFSLYPQFMFHLRRSQFLQVFNNSPDETSYYRHMLDIEDLTQSLIMIQPI 541

Query: 623 LYAYSFSGPPEPVLLDSSSILADRILLMDTFFQILIYHGETIAQWRKSGYQDMPEYENFR 682
           LYAYSF GPPEPVLLD++S+  DRILLMDTFF ++IYHGETI QW K+GY D+PEYENF+
Sbjct: 542 LYAYSFHGPPEPVLLDTNSLQPDRILLMDTFFHLVIYHGETIDQWNKAGYADLPEYENFK 721

Query: 683 HLLQAPVDDAQEILHSRFPMPRYIDTEHGGSQARFLLSKVNPSQTHNNMYAWGQESGAPI 742
            L+QAPVDDAQEIL +RFPMPRYI TE GGSQARFLLSKVNPSQTHNNMY +GQE+GA +
Sbjct: 722 QLMQAPVDDAQEILQTRFPMPRYIVTEFGGSQARFLLSKVNPSQTHNNMYGFGQEAGASV 901

Query: 743 LTDDVSLQVFMDHLKKLAVSSAA 765
           LTDDVSLQVFM+HLKKLAVSS++
Sbjct: 902 LTDDVSLQVFMEHLKKLAVSSSS 970
>04719
          Length = 443

 Score = 30.0 bits (66), Expect = 4.1,   Method: Composition-based stats.
 Identities = 22/62 (35%), Positives = 28/62 (45%), Gaps = 2/62 (3%)
 Frame = -3

Query: 12  EERDGVRFSWNVWP--SSRLEATRMVVPVAALFTPLKERPDLPPIQYEPVLCSRTTCRAV 69
           E R G R     WP  S+R+     V     LFTP +   D    QY+  LCS   CR++
Sbjct: 258 ESRSGSR-----WPRESARIRGHNYVPKEIILFTPFR*ADD----QYKRPLCSFCGCRSL 106

Query: 70  LN 71
            N
Sbjct: 105 TN 100
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|126090932|ref|NP_077155.2| nucleolar protein 5A [Mus
musculus]
         (580 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

10550                                                                 568   e-162
02001                                                                 275   5e-74
05297                                                                  94   1e-19
00700                                                                  54   2e-07
>10550
          Length = 1765

 Score =  568 bits (1465), Expect = e-162,   Method: Compositional matrix adjust.
 Identities = 279/423 (65%), Positives = 337/423 (79%), Gaps = 4/423 (0%)
 Frame = -2

Query: 4    LHVLFEHAVGYALLALKEVEEISLLLPQVEECVLNLGKFHNVVRLVAFCPFSSSQVALEN 63
            L+VLFEHAVGYAL  +KE +E++LL P+VE+ VL+L KF++VV+  A   F+++  AL+N
Sbjct: 1737 LYVLFEHAVGYALFQVKEFDELALLAPRVEQNVLDLSKFNSVVKFEALAAFTNAHNALDN 1558

Query: 64   ANAVSEGVVHEDLRLLLETYLP--SKKKKVLLGVGDPKIGAAIQEELGYNCQTGGVIAEI 121
             N VSEGV+HEDLR LL  ++P  SKK KV+LG+ D K+ AAI E L  +C T GVI +I
Sbjct: 1557 INCVSEGVLHEDLRTLLAKHVPKSSKKLKVMLGLADSKLAAAIVEALDISCVTTGVIPDI 1378

Query: 122  LRGVRLHFHNLV--KGLTDLSACKAQLGLGHSYSRAKVKFNVNRVDNMIIQSISLLDQLD 179
            LRG+R+HF  LV    L + +A KAQLGLGHSYSRAKVKFNV+RVDNMIIQSI+LLDQLD
Sbjct: 1377 LRGIRMHFAKLVGQHKLNEGTASKAQLGLGHSYSRAKVKFNVHRVDNMIIQSIALLDQLD 1198

Query: 180  KDINTFSMRVREWYGYHFPELVKIVNDNATYCRLAQFIGXXXXXXXXXXXXXXXITMDGA 239
            KDINTFSMR+REWY YHFPELVKIV DN  Y R  Q I                + MD A
Sbjct: 1197 KDINTFSMRIREWYSYHFPELVKIVPDNYLYARTVQVI-QDRKQMPEDNSQLEELLMDSA 1021

Query: 240  KAKAILDASRSSMGMDISAIDLINIESFSSRVVSLSEYRQSLHTYLRSKMSQVAPSLSAL 299
            K +A+LDA+R SMGMDI+ IDLINI++  +RV+ LSE+R+ L  YL  +M  VAP+L+AL
Sbjct: 1020 KCQAVLDAARVSMGMDIAPIDLINIQALCARVIGLSEFRKELSQYLMDRMQSVAPNLAAL 841

Query: 300  IGEAVGARLIAHAGSLTNLAKYPASTVQILGAEKALFRALKTRGNTPKYGLIFHSTFIGR 359
            IG+ VGARLIAHAGSLTNLAK PASTVQILGAEKALFRALKT+GNTPKYGLIFHSTFIGR
Sbjct: 840  IGDQVGARLIAHAGSLTNLAKCPASTVQILGAEKALFRALKTKGNTPKYGLIFHSTFIGR 661

Query: 360  AAAKNKGRISRYLANKCSIASRIDCFSEVPTSVFGEKLREQVEERLSFYETGEIPRKNLD 419
            A AKNKGRISRYLANKCSIASRIDCFS++P+S+FG+ LR+QVE+RL F+ETG+ P KN+D
Sbjct: 660  AGAKNKGRISRYLANKCSIASRIDCFSDMPSSIFGDHLRQQVEDRLKFFETGDTPAKNID 481

Query: 420  VMK 422
            +M+
Sbjct: 480  IMR 472
>02001
          Length = 4146

 Score =  275 bits (702), Expect = 5e-74,   Method: Compositional matrix adjust.
 Identities = 143/306 (46%), Positives = 194/306 (63%)
 Frame = -1

Query: 86   SKKKKVLLGVGDPKIGAAIQEELGYNCQTGGVIAEILRGVRLHFHNLVKGLTDLSACKAQ 145
            SK  +  L V D K+G  I+EE    C     I E++R +R    NLV    DL A    
Sbjct: 3849 SKDAQEELAVADAKLGNLIKEEFNIQCVANNNINELMRCIRSQLDNLVSD-KDLHAM--S 3679

Query: 146  LGLGHSYSRAKVKFNVNRVDNMIIQSISLLDQLDKDINTFSMRVREWYGYHFPELVKIVN 205
            LGL HS SR KVKF+ ++VD MI+Q+IS LD +DK+IN + MR REWY +HFPEL K+V 
Sbjct: 3678 LGLAHSLSRYKVKFSPDKVDTMIVQAISTLDDIDKEINNYHMRAREWYAWHFPELPKVVT 3499

Query: 206  DNATYCRLAQFIGXXXXXXXXXXXXXXXITMDGAKAKAILDASRSSMGMDISAIDLINIE 265
            ++  + R    +G                 ++      + +A+  SMG +IS  DL  I 
Sbjct: 3498 EHEAFIRTVMKLGNKQNATSCDLSDILPEEVE----TDVKEAAEISMGTEISDDDLTVIM 3331

Query: 266  SFSSRVVSLSEYRQSLHTYLRSKMSQVAPSLSALIGEAVGARLIAHAGSLTNLAKYPAST 325
                ++VSL EYR  L  YL+ +M  +AP+L+ L+GE VGARLI+HAGSL NLAK+PAST
Sbjct: 3330 YLCKQIVSLVEYRGQLFEYLKHRMGAIAPNLTVLVGELVGARLISHAGSLMNLAKHPAST 3151

Query: 326  VQILGAEKALFRALKTRGNTPKYGLIFHSTFIGRAAAKNKGRISRYLANKCSIASRIDCF 385
            VQILGAEKALFRALK++ +TPKYGLI+H++ +G+A  KNKG++SR LA K S+A+R+D  
Sbjct: 3150 VQILGAEKALFRALKSKHDTPKYGLIYHASLVGQANPKNKGKLSRMLAAKSSLAARVDAL 2971

Query: 386  SEVPTS 391
             +  T+
Sbjct: 2970 GDENTT 2953
>05297
          Length = 530

 Score = 94.4 bits (233), Expect = 1e-19,   Method: Compositional matrix adjust.
 Identities = 48/157 (30%), Positives = 88/157 (56%)
 Frame = +2

Query: 253 GMDISAIDLINIESFSSRVVSLSEYRQSLHTYLRSKMSQVAPSLSALIGEAVGARLIAHA 312
           G ++S  DL+++       V LSE ++ +  Y+ S+M+ +AP+LS ++G ++ A+L+  A
Sbjct: 5   GTELSDEDLMSVSEACDTAVGLSESKKHIFEYVESRMTFIAPNLSIIVGASIAAKLMGIA 184

Query: 313 GSLTNLAKYPASTVQILGAEKALFRALKTRGNTPKYGLIFHSTFIGRAAAKNKGRISRYL 372
           G LT L+K PA  + +LG++K       T    P  G I++S  + +     + + +R L
Sbjct: 185 GGLTYLSKMPADNIILLGSQKRTLSGFSTTAILPHTGFIYYSDTVQKLPPDLRRKAARLL 364

Query: 373 ANKCSIASRIDCFSEVPTSVFGEKLREQVEERLSFYE 409
           A K ++ +R+D F        G+ LR +VE +LS ++
Sbjct: 365 AGKTALCARVDGFHGSVDGKVGDDLRAEVEGKLSKWQ 475
>00700
          Length = 1051

 Score = 53.5 bits (127), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 38/184 (20%), Positives = 79/184 (42%)
 Frame = +1

Query: 167 MIIQSISLLDQLDKDINTFSMRVREWYGYHFPELVKIVNDNATYCRLAQFIGXXXXXXXX 226
           +I+ + ++  ++D +IN     V++ Y   FPEL  +V     Y    + +G        
Sbjct: 304 LIVDANNMTVEIDNEINVIHQFVKDVYNKRFPELESLVPTAMEYISTVKELGNNILEKSK 483

Query: 227 XXXXXXXITMDGAKAKAILDASRSSMGMDISAIDLINIESFSSRVVSLSEYRQSLHTYLR 286
                  I +  A    +   + ++ G ++S  DL+++       V LSE ++ +  Y+ 
Sbjct: 484 NNEALQEI-LTSATIMVVSVTASTTQGTELSDEDLMSVSEACDTAVGLSESKKHIFEYVE 660

Query: 287 SKMSQVAPSLSALIGEAVGARLIAHAGSLTNLAKYPASTVQILGAEKALFRALKTRGNTP 346
           S+M+ +AP+LS ++G ++               +  A  + +LG++K       T    P
Sbjct: 661 SRMTFIAPNLSIIVGASIA-------------VQXAADNIILLGSQKRTLSGFSTTAILP 801

Query: 347 KYGL 350
            + L
Sbjct: 802 PHRL 813
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31981185|ref|NP_067489.2| phosphofructokinase, muscle
[Mus musculus]
         (780 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

03664                                                                 561   e-160
05449                                                                 360   1e-99
27417                                                                  32   1.1  
>03664
          Length = 1237

 Score =  561 bits (1446), Expect = e-160,   Method: Compositional matrix adjust.
 Identities = 264/379 (69%), Positives = 313/379 (82%)
 Frame = +3

Query: 14  IGKAIAVLTSGGDAQGMNAAVRAVVRVGIFTGARVFFVHEGYQGLVDGGEHIREATWESV 73
           +G  I V TSGGD+QGMN AVRAVVR+G + G +V+ + EGYQG+VDGGE+I EATW SV
Sbjct: 99  VGNTIGVFTSGGDSQGMNGAVRAVVRMGFYLGCKVYVIREGYQGMVDGGENIEEATWASV 278

Query: 74  SMMLQLGGTVIGSARCKDFREREGRLRAAHNLVKRGITNLCVIGGDGSLTGADTFRSEWS 133
           S +LQLGGTVIGSAR  DFR+REGRL+AA NLVKRGITNL VIGGDGSLTGAD FR EW+
Sbjct: 279 SGILQLGGTVIGSARSADFRQREGRLKAAANLVKRGITNLVVIGGDGSLTGADLFRREWA 458

Query: 134 DLLNDFQKDGKITAEEATKSSYLNIVGLVGSIDNDFCGTDMTIGTDSALHRIVEIVDAIT 193
            LL + ++ G++T +E  +  +LNIVG+VGSIDNDFCGTDMTIGTDSALHRI+E VDAI+
Sbjct: 459 SLLTELKEKGELTGDEMVRCQHLNIVGMVGSIDNDFCGTDMTIGTDSALHRIIEAVDAIS 638

Query: 194 TTAQSHQRTFVLEVMGRHCGYLALVTSLSCGADWVFIPECPPDDDWEEHLCRRLSETRTR 253
           TTA SHQR FV+EVMGRHCGYLALV +L+C ADWVFIPE PP+ DW+  LC +L   R  
Sbjct: 639 TTAISHQRAFVMEVMGRHCGYLALVAALACEADWVFIPEWPPEGDWKTTLCNKLLSERKL 818

Query: 254 GSRLNIIIVAEGAIDKNGKPITSEDIKNLVVKRLGYDTRVTVLGHVQRGGTPSAFDRILG 313
           G RLNII+VAEGAID+ G  ITS+ +K+L+   L YDTRVTVLGHVQRGG+PSAFDRILG
Sbjct: 819 GQRLNIILVAEGAIDREGNSITSDQVKDLLTNELKYDTRVTVLGHVQRGGSPSAFDRILG 998

Query: 314 SRMGVEAVMALLEGTPDTPACVVSLSGNQAVRLPLMECVQVTKDVTKAMDEKRFDEAIKL 373
           SRMG EAV+AL++ TPDTPACVVSL GNQ VR+PLMECV  TKDV KAMD K F+EA++L
Sbjct: 999 SRMGAEAVLALMDATPDTPACVVSLEGNQTVRVPLMECVSRTKDVQKAMDMKNFEEAVQL 1178

Query: 374 RGRSFMNNWEVYKLLAHVR 392
           RG+SF NN   Y++L+ +R
Sbjct: 1179RGKSFQNNLTTYRMLSKLR 1235

 Score =  138 bits (348), Expect = 7e-33,   Method: Compositional matrix adjust.
 Identities = 109/359 (30%), Positives = 175/359 (48%), Gaps = 29/359 (8%)
 Frame = +3

Query: 401 HTVAVMNVGAPAAGMNAAVRSTVRIGLIQGNRVLVVHDGFEGLAKG--QIEEAGWSYVGG 458
           +T+ V   G  + GMN AVR+ VR+G   G +V V+ +G++G+  G   IEEA W+ V G
Sbjct: 105 NTIGVFTSGGDSQGMNGAVRAVVRMGFYLGCKVYVIREGYQGMVDGGENIEEATWASVSG 284

Query: 459 WTGQGGSKLGTKRTLPKKNLE---QISANITKFNIQGLVIIGGFEAYTGG---------- 505
               GG+ +G+ R+   +  E   + +AN+ K  I  LV+IGG  + TG           
Sbjct: 285 ILQLGGTVIGSARSADFRQREGRLKAAANLVKRGITNLVVIGGDGSLTGADLFRREWASL 464

Query: 506 -LELME-GRKQFDELC----IPFVVIPATVSNNVPGSDFSIGADTALNTICTTCDRIKQS 559
             EL E G    DE+     +  V +  ++ N+  G+D +IG D+AL+ I    D I  +
Sbjct: 465 LTELKEKGELTGDEMVRCQHLNIVGMVGSIDNDFCGTDMTIGTDSALHRIIEAVDAISTT 644

Query: 560 AAGTKRRVFIIETMGGYCGYXXXXXXXXXXXXXXYIFEEP------FTIRDLQVNVEHLV 613
           A  + +R F++E MG +CGY              +I E P       T+ +  ++   L 
Sbjct: 645 AI-SHQRAFVMEVMGRHCGYLALVAALACEADWVFIPEWPPEGDWKTTLCNKLLSERKLG 821

Query: 614 QKMKTT-VKRGLVLRNEKCNENYTTDFIFNLYSEEGKGIFDSRKNVLGHMQQGGSPTPFD 672
           Q++    V  G + R      + T+D + +L + E K  +D+R  VLGH+Q+GGSP+ FD
Sbjct: 822 QRLNIILVAEGAIDRE---GNSITSDQVKDLLTNELK--YDTRVTVLGHVQRGGSPSAFD 986

Query: 673 RNFATKMGAKAMNWMSGKIKESYRNGRIFANTPDS-GCVLGMRKRALVFQPVTELKDQT 730
           R   ++MGA+A+               +   TPD+  CV+ +     V  P+ E   +T
Sbjct: 987 RILGSRMGAEAVL-------------ALMDATPDTPACVVSLEGNQTVRVPLMECVSRT 1124
>05449
          Length = 724

 Score =  360 bits (924), Expect = 1e-99,   Method: Compositional matrix adjust.
 Identities = 169/240 (70%), Positives = 198/240 (82%), Gaps = 5/240 (2%)
 Frame = +3

Query: 158 IVGLVGSIDNDFCGTDMTIGTDSALHRIVEIVDAITTTAQSHQRTFVLEVMGRHCGYLAL 217
           IVG+VGSIDNDFCGTDMTIGTDSALHRI+E VDAI+TTA SHQR FV+EVMGRHCGYLAL
Sbjct: 3   IVGMVGSIDNDFCGTDMTIGTDSALHRIIEAVDAISTTAISHQRAFVMEVMGRHCGYLAL 182

Query: 218 VTSLSCGADWVFIPECPPDDDWEEHLCRRLSET-----RTRGSRLNIIIVAEGAIDKNGK 272
           V +L+C ADWVFIPE PP+ DW+  LC +L  +     R  G RLNII+VAEGAID+ G 
Sbjct: 183 VAALACEADWVFIPEWPPEGDWKTTLCNKLLSSVALQERKLGQRLNIILVAEGAIDREGN 362

Query: 273 PITSEDIKNLVVKRLGYDTRVTVLGHVQRGGTPSAFDRILGSRMGVEAVMALLEGTPDTP 332
            ITS+ +K+L+   L YDTRVTVLGHVQRGG+PSAFDRILGSRMG EAV+AL++ TPDTP
Sbjct: 363 SITSDQVKDLLTNELKYDTRVTVLGHVQRGGSPSAFDRILGSRMGAEAVLALMDATPDTP 542

Query: 333 ACVVSLSGNQAVRLPLMECVQVTKDVTKAMDEKRFDEAIKLRGRSFMNNWEVYKLLAHVR 392
           ACVVSL GNQ VR+PLMECV  TKDV KAMD K F+EA++LRG+SF NN   Y++L+ +R
Sbjct: 543 ACVVSLEGNQTVRVPLMECVSRTKDVQKAMDMKNFEEAVQLRGKSFQNNLTTYRMLSKLR 722

 Score = 79.3 bits (194), Expect = 6e-15,   Method: Compositional matrix adjust.
 Identities = 60/216 (27%), Positives = 100/216 (46%), Gaps = 13/216 (6%)
 Frame = +3

Query: 528 TVSNNVPGSDFSIGADTALNTICTTCDRIKQSAAGTKRRVFIIETMGGYCGYXXXXXXXX 587
           ++ N+  G+D +IG D+AL+ I    D I  +A  + +R F++E MG +CGY        
Sbjct: 21  SIDNDFCGTDMTIGTDSALHRIIEAVDAISTTAI-SHQRAFVMEVMGRHCGYLALVAALA 197

Query: 588 XXXXXXYIFEEP-----------FTIRDLQVNVEHLVQKMKTT-VKRGLVLRNEKCNENY 635
                 +I E P             +  + +    L Q++    V  G + R      + 
Sbjct: 198 CEADWVFIPEWPPEGDWKTTLCNKLLSSVALQERKLGQRLNIILVAEGAIDRE---GNSI 368

Query: 636 TTDFIFNLYSEEGKGIFDSRKNVLGHMQQGGSPTPFDRNFATKMGAKAMNWMSGKIKESY 695
           T+D + +L + E K  +D+R  VLGH+Q+GGSP+ FDR   ++MGA+A+           
Sbjct: 369 TSDQVKDLLTNELK--YDTRVTVLGHVQRGGSPSAFDRILGSRMGAEAVL---------- 512

Query: 696 RNGRIFANTPDS-GCVLGMRKRALVFQPVTELKDQT 730
               +   TPD+  CV+ +     V  P+ E   +T
Sbjct: 513 ---ALMDATPDTPACVVSLEGNQTVRVPLMECVSRT 611
>27417
          Length = 497

 Score = 32.0 bits (71), Expect = 1.1,   Method: Composition-based stats.
 Identities = 23/89 (25%), Positives = 42/89 (47%), Gaps = 4/89 (4%)
 Frame = -2

Query: 622 RGLVLRNEKCNENYTTDFIFNLYSEEGKGIFDSRKNVLGHMQQGGSPTP-FDRNFA---T 677
           RG V  +   +  +  D  F+ Y+  GKG  DS   V+  + + G P P +  + A   +
Sbjct: 331 RGSVKESSITSPXHARDNSFDSYTSYGKGSEDSIDEVVFEVDENGMPIPRYSSSTALNHS 152

Query: 678 KMGAKAMNWMSGKIKESYRNGRIFANTPD 706
           + G++  +   G +  S RN   + ++PD
Sbjct: 151 QEGSRRGSERDGNMYSSDRNSGFYRSSPD 65
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|70778897|ref|NP_038846.2| GTP binding protein 1 [Mus
musculus]
         (668 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

04497                                                                 560   e-160
14064                                                                 115   3e-64
20898                                                                 209   2e-54
15991                                                                  40   0.003
12417                                                                  34   0.20 
>04497
          Length = 1188

 Score =  560 bits (1443), Expect = e-160,   Method: Compositional matrix adjust.
 Identities = 283/392 (72%), Positives = 310/392 (79%)
 Frame = -2

Query: 179  VLTHGELDNGRGFARQKLFRHKHEIESGRTSSVGNDILGFDSEGNVVNKPDSHGGSLEWT 238
            VLTHGELDNGRGFARQKLFRHKHE+ESGRTSSVGNDILGFD+ GNVVNKPD   G L+W 
Sbjct: 1187 VLTHGELDNGRGFARQKLFRHKHEMESGRTSSVGNDILGFDASGNVVNKPDH--GHLDWI 1014

Query: 239  KICEKSSKVITFIDLAGHEKYLKTTVFGMTGHLPDFCMLMVGSNAGIVGMTKEHLGLALA 298
            KICE ++KVITFIDLAGHE+YLKTTVFGMTGH PDF MLM+G+NAG++GMTKEHLGLALA
Sbjct: 1013 KICEDAAKVITFIDLAGHERYLKTTVFGMTGHAPDFAMLMIGANAGVIGMTKEHLGLALA 834

Query: 299  LNVPVFVVVTKIDMCPANIXXXXXXXXXXXXXSPGCRKIPVLVQSKDDVIVTASNFSSER 358
            LNVPVFVVVTK+DMCP N+             SPGCRKIPV+VQ+KDDVI +A+NF+SER
Sbjct: 833  LNVPVFVVVTKVDMCPPNVLQETLKLLTRILKSPGCRKIPVIVQNKDDVICSATNFTSER 654

Query: 359  MCPIFQISNVTGENXXXXXXXXXXXSPRTSYREEEPAEFQIDDXXXXXXXXXXXXXXXXX 418
            MCP+FQ+SNVTGEN           S R      +P EFQIDD                 
Sbjct: 653  MCPVFQVSNVTGENLELLKMFLNLLSTRVKCDLSKPPEFQIDDTFSVPGVGTVVSGTLLQ 474

Query: 419  XXIKLNDTLLLGPDPLGNFLSIAVKSIHRKRMPVKEVRGGQTASFALKKIKRSSIRKGMV 478
              IKLNDTLLLGPD LG F  I +KSIHRKRMPV+EVRGGQTASFALKKIKRSSIRKGMV
Sbjct: 473  GYIKLNDTLLLGPDALGQFQPIVIKSIHRKRMPVREVRGGQTASFALKKIKRSSIRKGMV 294

Query: 479  MVSPRLNPQASWEFEAEILVLHHPTTISPRYQAMVHCGSIRQTATILSMDKDCLRTGDKA 538
            MVSPRL P+A WEFE EILVLHHPTTIS RYQAMVH GS+RQTATI+ M +  LRTGDKA
Sbjct: 293  MVSPRLEPKACWEFEGEILVLHHPTTISIRYQAMVHVGSVRQTATIIQMTEQHLRTGDKA 114

Query: 539  TVHFRFIKTPEYLHIDQRLVFREGRTKAVGTI 570
             V FRFIK PEYL  + RLVFREGRTKAVGTI
Sbjct: 113  QVRFRFIKNPEYLKPNMRLVFREGRTKAVGTI 18
>14064
          Length = 1723

 Score =  115 bits (289), Expect(5) = 3e-64,   Method: Compositional matrix adjust.
 Identities = 68/128 (53%), Positives = 85/128 (66%)
 Frame = +2

Query: 211 VGNDILGFDSEGNVVNKPDSHGGSLEWTKICEKSSKVITFIDLAGHEKYLKTTVFGMTGH 270
           +  DILGFD++G VVN  +    S+E  +IC+ SSK+IT IDLAGH +YL+TT+ G+TG+
Sbjct: 41  ISYDILGFDTKGQVVNYAECR--SVE--EICQSSSKLITLIDLAGHHRYLRTTIVGLTGN 208

Query: 271 LPDFCMLMVGSNAGIVGMTKEHLGLALALNVPVFVVVTKIDMCPANIXXXXXXXXXXXXX 330
            PDF ML+V + +GIVGMTKEHLG ALAL VPV VVV K+D C A               
Sbjct: 209 CPDFAMLVVSATSGIVGMTKEHLGYALALGVPVIVVVNKVDQCGAGKLQRLLTQLETILK 388

Query: 331 SPGCRKIP 338
           SP  RK P
Sbjct: 389 SPAVRKYP 412

 Score =  114 bits (286), Expect(5) = 3e-64,   Method: Compositional matrix adjust.
 Identities = 53/133 (39%), Positives = 84/133 (63%)
 Frame = +2

Query: 421 IKLNDTLLLGPDPLGNFLSIAVKSIHRKRMPVKEVRGGQTASFALKKIKRSSIRKGMVMV 480
           I+  + LLLGP   G F  + V+++HR RMP + ++ GQ AS AL  + R  +RKGMV++
Sbjct: 689 IREGEKLLLGPSDNGTFEDVKVRTVHRNRMPCRLIQAGQAASVALLDVDRERLRKGMVLL 868

Query: 481 SPRLNPQASWEFEAEILVLHHPTTISPRYQAMVHCGSIRQTATILSMDKDCLRTGDKATV 540
           SP  +     +FEA++ VL+H   I+  +Q  VH G++ QTA I +++K+ ++T +KA V
Sbjct: 869 SPSSSVVCCKQFEADVYVLYHCNKITKNFQTTVHIGTVCQTAVITTINKNHIKTNEKARV 1048

Query: 541 HFRFIKTPEYLHI 553
            F F   PEY+ +
Sbjct: 1049VFTFKFKPEYIRV 1087

 Score = 52.0 bits (123), Expect(5) = 3e-64,   Method: Compositional matrix adjust.
 Identities = 31/80 (38%), Positives = 41/80 (51%), Gaps = 10/80 (12%)
 Frame = +1

Query: 332 PGCRKIPVLVQSKDDVIVTA-----SNFSSERMCPIFQISNVTGENXXXXXXXXXXXSPR 386
           PGC+KIP  V S+DD I  A     +N   +R+ PIF++S VTG N            P+
Sbjct: 391 PGCKKIPFQVNSEDDAITVAHSLETNNVIVDRITPIFKVSCVTGHNLDLILKFLHLLPPQ 570

Query: 387 TSYREEEP-----AEFQIDD 401
            S+ E E       EFQID+
Sbjct: 571 RSHTERERLSQDLTEFQIDE 630

 Score = 22.3 bits (46), Expect(5) = 3e-64,   Method: Compositional matrix adjust.
 Identities = 9/11 (81%), Positives = 10/11 (90%)
 Frame = +3

Query: 199 HKHEIESGRTS 209
           H HEI+SGRTS
Sbjct: 3   HLHEIQSGRTS 35

 Score = 21.6 bits (44), Expect(5) = 3e-64,   Method: Compositional matrix adjust.
 Identities = 8/13 (61%), Positives = 11/13 (84%)
 Frame = +1

Query: 556  RLVFREGRTKAVG 568
            RL+FR+G+TK  G
Sbjct: 1093 RLLFRDGKTKG*G 1131
>20898
          Length = 840

 Score =  209 bits (533), Expect = 2e-54,   Method: Compositional matrix adjust.
 Identities = 100/123 (81%), Positives = 106/123 (86%)
 Frame = -1

Query: 452 VKEVRGGQTASFALKKIKRSSIRKGMVMVSPRLNPQASWEFEAEILVLHHPTTISPRYQA 511
           V+EVRGGQTASFALKKIKRSSIRKGMVMVSPRL P+A WEFE EILVLHHPTTIS RYQA
Sbjct: 840 VREVRGGQTASFALKKIKRSSIRKGMVMVSPRLEPKACWEFEGEILVLHHPTTISIRYQA 661

Query: 512 MVHCGSIRQTATILSMDKDCLRTGDKATVHFRFIKTPEYLHIDQRLVFREGRTKAVGTIT 571
           MVH GS+RQTATI+ M +  LRTGDKA V FRFIK PEYL  + RLVFREGRTKAVGTIT
Sbjct: 660 MVHVGSVRQTATIIQMTEQHLRTGDKAQVRFRFIKNPEYLKPNMRLVFREGRTKAVGTIT 481

Query: 572 KLL 574
            L 
Sbjct: 480 NLF 472
>15991
          Length = 1629

 Score = 40.4 bits (93), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 25/96 (26%), Positives = 46/96 (47%), Gaps = 5/96 (5%)
 Frame = -3

Query: 425 DTLLLGPDPLGNF----LSIAVKSIHRKRMPVKEVRGGQTASFALKKIKRSSIRKGMVMV 480
           +T +L P  +  F    L+  VKS+      ++E   G    F +K +    IR+G V  
Sbjct: 880 ETGILKPGTVVTFAPGGLTTEVKSVEMHHEQLQEALPGDNVGFNVKNVSVKDIRRGNVAG 701

Query: 481 SPRLN-PQASWEFEAEILVLHHPTTISPRYQAMVHC 515
             + + P+ +  F A++++L+HP  I   Y  ++ C
Sbjct: 700 DSKNDPPKGAKNFYAQVIILNHPGMIHAGYAPVLDC 593
>12417
          Length = 954

 Score = 33.9 bits (76), Expect = 0.20,   Method: Compositional matrix adjust.
 Identities = 29/89 (32%), Positives = 38/89 (42%), Gaps = 12/89 (13%)
 Frame = +2

Query: 171 AGKSTLLGVLTHGELDNGRGFARQKLFRHKHEIESGRTSSVGNDILGFD----------- 219
           A K TL   + H ++D  R FAR K    +HE E G     G D L  +           
Sbjct: 665 APKRTLHPTMRH-KMDRDRLFARDKEVMSRHESEEGDYFPDGTDALKIELPPIVTEQPLL 841

Query: 220 -SEGNVVNKPDSHGGSLEWTKICEKSSKV 247
              G V+ KPD+H   L+  +I E   KV
Sbjct: 842 MRGGRVMKKPDTHDEWLQ--RIKEAEEKV 922
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|82919017|ref|XP_928308.1| PREDICTED: similar to
CCR4-NOT transcription complex, subunit 1 isoform a isoform 30 [Mus
musculus]
         (2383 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

15030                                                                 482   e-159
01657                                                                 279   1e-74
36991                                                                 192   1e-48
31187                                                                 184   4e-46
27543                                                                 118   6e-41
27905                                                                 150   7e-36
>15030
          Length = 1392

 Score =  482 bits (1240), Expect(3) = e-159,   Method: Compositional matrix adjust.
 Identities = 229/308 (74%), Positives = 257/308 (83%), Gaps = 3/308 (0%)
 Frame = -1

Query: 1826 GGPN---FMMHSGISQASEYDDPPGLREKAEYLLREWVNLYHSAAAGRDSTKAFSAFVGQ 1882
            GGP     MM SGI+QA E+DDPPGL EK EYLLREWVN+YHS AAGRDSTKAF+ FV Q
Sbjct: 891  GGPGNATTMMQSGITQAREFDDPPGLHEKTEYLLREWVNMYHSPAAGRDSTKAFTCFVQQ 712

Query: 1883 VELLERKMHQQGILKTDDLITRFFRLCTEMCVEISYRAQAEQQHNPAANPTMIRAKCYHN 1942
                   MHQQGILKTDDLITRFFRLCTEMCV++ YRA  EQ    + +PT++RAKC+H 
Sbjct: 711  -------MHQQGILKTDDLITRFFRLCTEMCVDLCYRALGEQ----SQSPTLVRAKCFHT 565

Query: 1943 LDAFVRLIALLVKHSGEATNTVTKINLLNKVLGIVVGVLLQDHDVRQSEFQQLPYHRIFI 2002
            LDAFVRLIALLVKHSG+ +NTVTKINLLNK LGIV GVLLQDH+VR +EFQQLPYHRIFI
Sbjct: 564  LDAFVRLIALLVKHSGDNSNTVTKINLLNKXLGIVAGVLLQDHEVRYTEFQQLPYHRIFI 385

Query: 2003 MLLLELNAPEHVLETINFQTLTAFCNTFHILRPTKAPGFVYAWLELISHRIFIARMLAHT 2062
            ML +ELNAPE +LE IN+Q L AFC  FHILRP+KAP F +AW+ELISHR+FI R+LA T
Sbjct: 384  MLFIELNAPEPILEGINYQVLAAFCQVFHILRPSKAPAFSFAWMELISHRVFIGRLLALT 205

Query: 2063 PQQKGWPMYAQLLIDLFKYLAPFLRNVELTKPMQILYKGTLRVLLVLLHDFPEFLCDYHY 2122
            P Q+GW MYAQL++ LFK+LAPFLRN EL K  Q+LYKGTLRVLLVLLHDFPEFLCDYHY
Sbjct: 204  PGQRGWGMYAQLMMGLFKFLAPFLRNAELQKSTQLLYKGTLRVLLVLLHDFPEFLCDYHY 25

Query: 2123 GFCDVIPP 2130
             FCDVIPP
Sbjct: 24   TFCDVIPP 1

 Score = 92.8 bits (229), Expect(3) = e-159,   Method: Compositional matrix adjust.
 Identities = 47/92 (51%), Positives = 64/92 (69%), Gaps = 6/92 (6%)
 Frame = -2

Query: 1667 EGLLD-----ATSGADADLLLRYRECHLLVLKALQDGRAYGSPWCNKQITRCLI-ECRDE 1720
            EGLL+     A +    +LLLR+RECHL+VLK L D RA G  W  K+ITRCLI   R+E
Sbjct: 1391 EGLLEHYIPSAITSEQQELLLRFRECHLMVLKGLADARALGPSWAPKEITRCLILMGREE 1212

Query: 1721 YKYNVEAVELLIRNHLVNMQQYDLHLAQSMEN 1752
             KYN+EAVE L+R+ L++  Q+D++L+  +EN
Sbjct: 1211 SKYNLEAVETLMRSGLMSTNQFDVYLSSVLEN 1116

 Score = 31.2 bits (69), Expect(3) = e-159,   Method: Compositional matrix adjust.
 Identities = 18/51 (35%), Positives = 29/51 (56%), Gaps = 1/51 (1%)
 Frame = -3

Query: 1761 FAMQLVKILLVDERSVAH-ITEADLFHTIETLMRINAHSRGNAPEGLPQLM 1810
            F MQL++ +  D+++  H  +E D   T++ L  +   SR  +PEGL  LM
Sbjct: 1093 FVMQLMQRICADDKNSPHSFSENDFPQTVDALNTLAVRSR-QSPEGLEGLM 944
>01657
          Length = 1088

 Score =  279 bits (713), Expect = 1e-74,   Method: Compositional matrix adjust.
 Identities = 129/162 (79%), Positives = 143/162 (88%)
 Frame = -1

Query: 2216 RYNLQLINALVLYVGTQAIAHIHNKGSTPSMSTITHSAHMDIFQNLAVDLDTEGRYLFLN 2275
            RYN+ L+NALV+YVGTQAIA I NK   P+ S I HSAHMDIFQNLAVDLDTEGRYLFLN
Sbjct: 1082 RYNMTLMNALVMYVGTQAIALIRNKNFVPNTSNIAHSAHMDIFQNLAVDLDTEGRYLFLN 903

Query: 2276 AIANQLRYPNSHTHYFSCTMLYLFAEANTEAIQEQITRVLLERLIVNRPHPWGLLITFIE 2335
            AIANQLRYPNSHTHYFSC +L+LFAEAN+EAIQEQITRVLLERLIVNRPHPWGLLITFIE
Sbjct: 902  AIANQLRYPNSHTHYFSCAVLHLFAEANSEAIQEQITRVLLERLIVNRPHPWGLLITFIE 723

Query: 2336 LIKNPAFKFWNHEFVHCAPEIEKLFQSVAQCCMGQKQAQQVM 2377
            LIKNP +KFW+H+FVHCAPEI KLF+SVA+ C+ +    Q M
Sbjct: 722  LIKNPIYKFWDHDFVHCAPEITKLFESVARSCLAKSNVTQQM 597
>36991
          Length = 633

 Score =  192 bits (489), Expect = 1e-48,   Method: Compositional matrix adjust.
 Identities = 90/149 (60%), Positives = 114/149 (76%)
 Frame = -1

Query: 1   MNLDSLSLALSQISYLVDNLTKKNYRASQQEIQHIVNRHGPEADRHLLRCLFSHVDFSGD 60
           MNLDSLS AL++IS+ V NLTKKNY++S   I H+V +HG EADRHL RCL SH+DFSGD
Sbjct: 447 MNLDSLSFALAEISFSVANLTKKNYKSSVAGINHLVAKHGAEADRHLFRCLLSHIDFSGD 268

Query: 61  GKSSGKDFHQTQFLIQECASLITKPNFISTLSYAIDNPLHYQKSLKPAPHLFAQLSKVLK 120
           GKSSGKD +Q Q+L  +    + +PNF+S L YAID+PLH+QK+LKP+  L  QLSKVLK
Sbjct: 267 GKSSGKDLYQIQYLTVDSNHFLGRPNFVSILCYAIDDPLHHQKTLKPSAQLLPQLSKVLK 88

Query: 121 LSKVQEVIFGLALLNSSSPDLRGFAAQFI 149
           L++VQEV++   LLNSS  D   +A QF+
Sbjct: 87  LNRVQEVVYAFGLLNSSKQDTVQYATQFL 1
>31187
          Length = 391

 Score =  184 bits (467), Expect = 4e-46,   Method: Compositional matrix adjust.
 Identities = 87/120 (72%), Positives = 99/120 (82%), Gaps = 4/120 (3%)
 Frame = -2

Query: 2252 SAHMDIFQNLAVDLDTEGRYLFLNAIANQLRYPNSHTHYFSCTMLYLFAEANTEAIQEQI 2311
            S HMDI +            LFL AI+NQLRYPNSHTHYFSC +LYLFA+A++EA+QEQI
Sbjct: 372  STHMDISRTWPSTSTQRVGTLFLTAISNQLRYPNSHTHYFSCCLLYLFAQAHSEAVQEQI 193

Query: 2312 TRVLLERLIVNRPHPWGLLITFIELIKNPAFKFWNHEFVHCAPEIE----KLFQSVAQCC 2367
            TRVLLERLIVNRPHPWGLLITFIELIKNP+FKFW+HEFVHCAPEIE    +LF+SVA+ C
Sbjct: 192  TRVLLERLIVNRPHPWGLLITFIELIKNPSFKFWHHEFVHCAPEIENVCRRLFESVARSC 13
>27543
          Length = 391

 Score =  118 bits (295), Expect(2) = 6e-41,   Method: Composition-based stats.
 Identities = 59/79 (74%), Positives = 63/79 (79%), Gaps = 1/79 (1%)
 Frame = +3

Query: 1134 LVMKRVSIEPNFHSLYSNFLDTLKNPEFNKMVLNETYRNIKVLLTSD-KAAANFSDRSLL 1192
            LVMKR SIEPNFH LYS+F+D LK  +  KMVL ETYRNIKVLL SD K  ANFSDRSLL
Sbjct: 3    LVMKRASIEPNFHVLYSSFIDVLKIMQLTKMVLKETYRNIKVLLQSDIKGVANFSDRSLL 182

Query: 1193 KNLGHWLGMITLAKNKPIL 1211
            KNLGHWLGM+TL K  P L
Sbjct: 183  KNLGHWLGMMTLGKINPSL 239

 Score = 70.5 bits (171), Expect(2) = 6e-41,   Method: Composition-based stats.
 Identities = 34/50 (68%), Positives = 41/50 (82%)
 Frame = +2

Query: 1206 KNKPILHTDLDVKSLLLEAYVKGQQELLYVVPFVAKVLESSIRSLVFRPP 1255
            ++KPIL TD+D+KSL+ EAY KG QELLYVVPF AKVLES  +S VF+ P
Sbjct: 221  QDKPILMTDMDLKSLVYEAYQKGAQELLYVVPFTAKVLESCAKSKVFKAP 370
>27905
          Length = 839

 Score =  150 bits (379), Expect = 7e-36,   Method: Compositional matrix adjust.
 Identities = 94/232 (40%), Positives = 130/232 (56%), Gaps = 4/232 (1%)
 Frame = +3

Query: 228 YPEKRDILMDRILPDSGGVAKTMMESSLADFMQEVGYGFCASIEECRNIIMQFGVREVTA 287
           YP++   L D + P  GG       S L   +Q+ G   C +           G+RE+  
Sbjct: 225 YPQQHAFLHDGVQP--GGANHG---SWLCLHIQQGGVSQCDA-----------GLRELNP 356

Query: 288 AQVARVLGMMARTHSGLTDGIPLQSISAPGSGIWSDGKDKSEGAQAHTWNVEVLIDVLKE 347
             VARVLGMMART +GL +    QS S+     W +   K+E     TWNVE  I V ++
Sbjct: 357 QAVARVLGMMARTITGLGE----QSQSS----WWGE---KTETPGVTTWNVETFIQVTRD 503

Query: 348 LNPSLNFKEVTYELDHPGFQIRDSKGLHNVVYGIQRGLGME--VFPVDFIYRPWKHAEGQ 405
           L   L++K+V  +LDHPGF I   KGL  +V G+QRGL +    FP+  I+RPW + EGQ
Sbjct: 504 LAGMLDWKDVVAQLDHPGFIINSKKGLRLLVEGLQRGLQLSNTAFPIHHIFRPWNNTEGQ 683

Query: 406 LSFIQHSLINPEVFCFADYPCHT--VATDILKAPPEDDNREIATWKSLDLIE 455
           LS I   L + +V CFADY   T  V  ++LK+ P DD+RE++TWK L+++E
Sbjct: 684 LSLILACLRHHDVMCFADYLSVTEVVVCEVLKSAPSDDDREVSTWKCLNMVE 839

 Score = 97.4 bits (241), Expect = 7e-20,   Method: Composition-based stats.
 Identities = 48/114 (42%), Positives = 74/114 (64%)
 Frame = +1

Query: 165 VSGNQEGGFQDIAIEVXXXXXXXXXFGQKGAFGVGQEQIDAFLKTLRRDFPQERCPVVLA 224
           V+G QEGG QD  +E           G + A+G+G+EQ +A LKTL+RDFP+ER P +L+
Sbjct: 1   VTGRQEGGLQDAGVEALHLLLSHLLRG-RDAYGIGKEQKEALLKTLQRDFPRERVPAILS 177

Query: 225 PLLYPEKRDILMDRILPDSGGVAKTMMESSLADFMQEVGYGFCASIEECRNIIM 278
            LLYP+  DI + +++     +  +MMES+LA+ + E GY   +S EECR++++
Sbjct: 178 YLLYPDVVDISVTQLI-TLNNMPSSMMESNLAELIMEAGYACTSSKEECRSVML 336
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31980969|ref|NP_062761.2| SEC23B [Mus musculus]
         (767 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

11155                                                                 549   e-156
>11155
          Length = 1328

 Score =  549 bits (1415), Expect = e-156,   Method: Compositional matrix adjust.
 Identities = 250/323 (77%), Positives = 291/323 (90%)
 Frame = +2

Query: 445 TSQWKICGLDPSSTLGIYFEVVNQHNAPVPQGGRGAIQFVTQYQHSSTQKRIRVTTIARN 504
           T QWK+CGL P+++LG++FEVVNQHNAP+PQGGRG +QF+TQYQHSS Q+R+RVTT+ARN
Sbjct: 2   TCQWKMCGLYPNTSLGVFFEVVNQHNAPIPQGGRGYLQFITQYQHSSGQRRVRVTTVARN 181

Query: 505 WADAQSQLRHIEAAFDQEAAAVLMARLGVFRAESEEGPDVLRWLDRQLIRLCQKFGQYNK 564
           WADA + ++HI A FDQEA+AVLM R+ V+RAE+++GPDVLRWLDR LIRLCQKFG+Y+K
Sbjct: 182 WADASTNIQHISAGFDQEASAVLMGRIAVYRAETDDGPDVLRWLDRMLIRLCQKFGEYHK 361

Query: 565 EDPTSFRLSDSFSLYPQFMFHLRRSPFLQVFNNSPDESSYYRHHFARQDLTQSLIMIQPI 624
           +DP SFR S++FSLYPQFMFHLRRS FLQVFNNSPDE+SYYRH    +DLTQSLIMIQPI
Sbjct: 362 DDPNSFRFSENFSLYPQFMFHLRRSQFLQVFNNSPDETSYYRHMLDIEDLTQSLIMIQPI 541

Query: 625 LYSYSFHGPPEPVLLDSSSILADRILLMDTFFQIVIYLGETIAQWRKAGYQDMPEYENFK 684
           LY+YSFHGPPEPVLLD++S+  DRILLMDTFF +VIY GETI QW KAGY D+PEYENFK
Sbjct: 542 LYAYSFHGPPEPVLLDTNSLQPDRILLMDTFFHLVIYHGETIDQWNKAGYADLPEYENFK 721

Query: 685 HLLQAPLDDAQEILQARFPMPRYINTEHGGSQARFLLSKVNPSQTHNNLYAWGQETGAPI 744
            L+QAP+DDAQEILQ RFPMPRYI TE GGSQARFLLSKVNPSQTHNN+Y +GQE GA +
Sbjct: 722 QLMQAPVDDAQEILQTRFPMPRYIVTEFGGSQARFLLSKVNPSQTHNNMYGFGQEAGASV 901

Query: 745 LTDDVSLQVFMDHLKKLAVSSAS 767
           LTDDVSLQVFM+HLKKLAVSS+S
Sbjct: 902 LTDDVSLQVFMEHLKKLAVSSSS 970
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|33859660|ref|NP_036154.1| epsilon isoform of
regulatory subunit B56, protein phosphatase 2A [Mus musculus]
         (467 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

00299                                                                 497   e-156
01605                                                                 473   e-133
05988                                                                 205   3e-53
23660                                                                  29   4.3  
>00299
          Length = 1481

 Score =  497 bits (1280), Expect(2) = e-156,   Method: Compositional matrix adjust.
 Identities = 240/327 (73%), Positives = 281/327 (85%), Gaps = 4/327 (1%)
 Frame = +1

Query: 44  ELTPLPLLKDVPTSEQPELFLKKLQQCCVIFDFM-DTLSDLKMKEYKRSTLNELVDYITI 102
           EL  L LLKD   +E+ ELF++KL+QC V+FDF+ D LSDLK KE KR+ LNE+V+Y+T 
Sbjct: 313 ELQKLALLKDATPAEREELFVQKLRQCIVLFDFVQDPLSDLKWKEVKRAALNEMVEYVTQ 492

Query: 103 SRGCLTEQTYPEVVRMVSCNIFRTLPPSDS---NEFDPEEDEPTLEASWPHLQLVYEFFI 159
           +RG +TE  YPE + M + N+FRTLPPS +    EFDPEEDEPTLEA+WPHLQLVYEFF+
Sbjct: 493 NRGVITEAIYPEAITMFAVNLFRTLPPSSNPSGAEFDPEEDEPTLEAAWPHLQLVYEFFL 672

Query: 160 RFLESQEFQPSIAKKYIDQKFVLQLLELFDSEDPRERDYLKTVLHRIYGKFLGLRAFIRK 219
           RFLES +FQP+  K+YIDQKFVLQLL+LFDSEDPRERD+LKT+LHRIYGKFLGLRAFIRK
Sbjct: 673 RFLESPDFQPNTVKRYIDQKFVLQLLDLFDSEDPRERDFLKTILHRIYGKFLGLRAFIRK 852

Query: 220 QINNIFLRFVYETEHFNGVAELLEILGSIINGFALPLKAEHKQFLVKVLIPLHTVRSLSL 279
            INNIF  F+YETEH NG+AELLEILGSIINGFALPLK EHK FL+KVL+PLH V+SLS+
Sbjct: 853 HINNIFYSFIYETEHHNGIAELLEILGSIINGFALPLKEEHKIFLLKVLLPLHKVKSLSV 1032

Query: 280 FHAQLAYCIVQFLEKDPSLTEPVIRGLMKFWPKTCSQKEVMFLGELEEILDVIEPSQFVK 339
           +H QLAYC+VQFLEKDP+LTE VI GL+K+WPK  S KEVMFL ELEEILDVIEP++F K
Sbjct: 1033YHPQLAYCVVQFLEKDPNLTEQVIMGLLKYWPKVHSPKEVMFLNELEEILDVIEPAEFTK 1212

Query: 340 IQEPLFKQIAKCVSSPHFQVAERALYY 366
           +  PLFKQ+AKCVSSPHFQVAERALY+
Sbjct: 1213VMVPLFKQLAKCVSSPHFQVAERALYF 1293

 Score = 73.6 bits (179), Expect(2) = e-156,   Method: Compositional matrix adjust.
 Identities = 33/53 (62%), Positives = 42/53 (79%)
 Frame = +3

Query: 366  YWNNEYIMSLIEENSNVILPIMFSSLYRISKEHWNPAIVALVYNVLKAFMEMN 418
            +WNNEYI+SLI +N + I+P+MF +LY+ SKEHWN  I  L+YN LK FMEMN
Sbjct: 1290 FWNNEYILSLISDNVSSIMPLMFPALYK-SKEHWNKTIHGLIYNALKLFMEMN 1445
>01605
          Length = 971

 Score =  473 bits (1216), Expect = e-133,   Method: Compositional matrix adjust.
 Identities = 228/310 (73%), Positives = 267/310 (86%), Gaps = 4/310 (1%)
 Frame = -3

Query: 58  EQPELFLKKLQQCCVIFDFM-DTLSDLKMKEYKRSTLNELVDYITISRGCLTEQTYPEVV 116
           E+ ELF++K++QC V+FDF+ D LSDLK KE KR+ LNE+V+++T +RG +TE  YPE +
Sbjct: 969 EREELFVQKIRQCSVLFDFVQDPLSDLKWKEVKRAALNEMVEFVTQNRGVVTEPIYPEAI 790

Query: 117 RMVSCNIFRTLPPS---DSNEFDPEEDEPTLEASWPHLQLVYEFFIRFLESQEFQPSIAK 173
            M S N+FRTLPPS   +  EFDPEEDEPTLEA+WPHLQL+YEFF+RFLES +FQP+ AK
Sbjct: 789 TMFSVNLFRTLPPSSNPNGAEFDPEEDEPTLEAAWPHLQLIYEFFLRFLESPDFQPNTAK 610

Query: 174 KYIDQKFVLQLLELFDSEDPRERDYLKTVLHRIYGKFLGLRAFIRKQINNIFLRFVYETE 233
           +YIDQKFVLQLL+LFDSEDPRERD+LKT+LHRIYGKFLGLRAFIRK INNIF  F+YETE
Sbjct: 609 RYIDQKFVLQLLDLFDSEDPRERDFLKTILHRIYGKFLGLRAFIRKHINNIFYSFIYETE 430

Query: 234 HFNGVAELLEILGSIINGFALPLKAEHKQFLVKVLIPLHTVRSLSLFHAQLAYCIVQFLE 293
           H NG+AELLEILGSIINGFALPLK EHK FL+KVL+PLH V+SLS++H QLAYC+VQFLE
Sbjct: 429 HHNGIAELLEILGSIINGFALPLKEEHKTFLLKVLLPLHKVKSLSVYHPQLAYCVVQFLE 250

Query: 294 KDPSLTEPVIRGLMKFWPKTCSQKEVMFLGELEEILDVIEPSQFVKIQEPLFKQIAKCVS 353
           KDPSLTE VI GL+KFWPK  S KEVMFL ELEEILDVIEP++F K+  PLFKQ+AKCVS
Sbjct: 249 KDPSLTEQVIIGLLKFWPKVHSPKEVMFLNELEEILDVIEPAEFTKVMGPLFKQLAKCVS 70

Query: 354 SPHFQVAERA 363
           SPHFQ   R 
Sbjct: 69  SPHFQNDTRV 40
>05988
          Length = 569

 Score =  205 bits (521), Expect = 3e-53,   Method: Compositional matrix adjust.
 Identities = 99/124 (79%), Positives = 111/124 (89%)
 Frame = +2

Query: 243 EILGSIINGFALPLKAEHKQFLVKVLIPLHTVRSLSLFHAQLAYCIVQFLEKDPSLTEPV 302
           EILGSIINGFALPLK EHK FL+KVL+PLH V+SLS++H QLAYC+VQFLEKDPSLTE V
Sbjct: 2   EILGSIINGFALPLKEEHKTFLLKVLLPLHKVKSLSVYHPQLAYCVVQFLEKDPSLTEQV 181

Query: 303 IRGLMKFWPKTCSQKEVMFLGELEEILDVIEPSQFVKIQEPLFKQIAKCVSSPHFQVAER 362
           I GL+KFWPK  S KEVMFL ELEEILDVIEP++F K+  PLFKQ+AKCVSSPHFQVAER
Sbjct: 182 IIGLLKFWPKVHSPKEVMFLNELEEILDVIEPAEFTKVMGPLFKQLAKCVSSPHFQVAER 361

Query: 363 ALYY 366
           ALY+
Sbjct: 362 ALYF 373

 Score = 87.8 bits (216), Expect = 8e-18,   Method: Compositional matrix adjust.
 Identities = 40/82 (48%), Positives = 55/82 (67%)
 Frame = +1

Query: 351 CVSSPHFQVAERALYYWNNEYIMSLIEENSNVILPIMFSSLYRISKEHWNPAIVALVYNV 410
           C+ S  F        +WNNEYI+SLI +N + ++P+MF +LY+ SKEHWN  I  L+YN 
Sbjct: 328 CLKSA-FSGGRTCSVFWNNEYILSLISDNVSSVMPLMFPALYK-SKEHWNKTIHGLIYNA 501

Query: 411 LKAFMEMNSTMFDELTATYKSD 432
           LK FMEMN  +FD+ T  YK++
Sbjct: 502 LKLFMEMNQKLFDDCTQQYKAE 567
>23660
          Length = 1021

 Score = 28.9 bits (63), Expect = 4.3,   Method: Compositional matrix adjust.
 Identities = 14/37 (37%), Positives = 24/37 (64%)
 Frame = +3

Query: 244 ILGSIINGFALPLKAEHKQFLVKVLIPLHTVRSLSLF 280
           I G+I +GFA  ++ +  Q L + L+ ++T  +LSLF
Sbjct: 732 IFGNIPDGFATMIQVKESQNLCESLLKMYTYLTLSLF 842
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|7110703|ref|NP_032976.1| protease (prosome,
macropain) 26S subunit, ATPase 5 [Mus musculus]
         (406 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

19129                                                                 548   e-156
07243                                                                 315   1e-86
23766                                                                 271   1e-84
01642                                                                 285   2e-77
07247                                                                 237   2e-74
02582                                                                 177   5e-45
12235                                                                 160   1e-39
03022                                                                 150   8e-37
26408                                                                 123   2e-28
00810                                                                 107   8e-24
20270                                                                 103   2e-22
38672                                                                  83   3e-21
25671                                                                  84   1e-16
02194                                                                  67   1e-11
17843                                                                  62   3e-10
26887                                                                  51   7e-07
06766                                                                  45   6e-05
19561                                                                  44   1e-04
14413                                                                  44   1e-04
01279                                                                  34   0.086
37695                                                                  34   0.12 
05247                                                                  32   0.47 
02744                                                                  31   0.94 
>19129
          Length = 1020

 Score =  548 bits (1412), Expect = e-156,   Method: Compositional matrix adjust.
 Identities = 272/321 (84%), Positives = 284/321 (88%), Gaps = 1/321 (0%)
 Frame = +1

Query: 7   EQMELEEGKAG-SGLRQYYLSKIEELQLIVNDKSQNLRRLQAQRNELNAKVXXXXXXXXX 65
           EQME+E    G  G++QYY+SKIEE QLIVN+K+QNLRRL+AQRNELNAKV         
Sbjct: 58  EQMEIEGAPVGHEGIKQYYISKIEEQQLIVNEKTQNLRRLEAQRNELNAKVRMLREELQL 237

Query: 66  XXXXGSYVGEVVRAMDKKKVLVKVHPEGKFXXXXXXXXXXXXXTPNCRVALRNDSYTLHK 125
               GSYVGEVV+ MDKKKVLVKVHPEGKF             TPNCRVALRNDSY LHK
Sbjct: 238 LQEQGSYVGEVVKPMDKKKVLVKVHPEGKFVVDIDKNIDMNSVTPNCRVALRNDSYVLHK 417

Query: 126 ILPNKVDPLVSLMMVEKVPDSTYEMIGGLDKQIKEIKEVIELPVKHPELFEALGIAQPKG 185
           ILPNKVDPLVSLMMVEKVPDSTYEM+GGLDKQIKEIKEVIELPVKHPELFEALGIAQPKG
Sbjct: 418 ILPNKVDPLVSLMMVEKVPDSTYEMVGGLDKQIKEIKEVIELPVKHPELFEALGIAQPKG 597

Query: 186 VLLYGPPGTGKTLLARAVAHHTDCTFIRVSGSELVQKFIGEGARMVRELFVMAREHAPSI 245
           VLLYGPPGTGKTLLARAVAHHT+CTFIRVSGSELVQKFIGEG+RMVRELFVMAREHAPSI
Sbjct: 598 VLLYGPPGTGKTLLARAVAHHTECTFIRVSGSELVQKFIGEGSRMVRELFVMAREHAPSI 777

Query: 246 IFMDEIDSIGSSRLEGGSGGDSEVQRTMLELLNQLDGFEATKNIKVIMATNRIDILDSAL 305
           IFMDEIDSIGSSRLEGGSGGDSEVQRTMLELLNQLDGFE  +NIKVIMATNRIDILDSAL
Sbjct: 778 IFMDEIDSIGSSRLEGGSGGDSEVQRTMLELLNQLDGFEPKQNIKVIMATNRIDILDSAL 957

Query: 306 LRPGRIDRKIEFPPPNEEARL 326
           LRPGRIDRKIEFPPPNEEARL
Sbjct: 958 LRPGRIDRKIEFPPPNEEARL 1020
>07243
          Length = 1112

 Score =  315 bits (808), Expect = 1e-86,   Method: Compositional matrix adjust.
 Identities = 157/278 (56%), Positives = 201/278 (72%)
 Frame = +1

Query: 113 RVALRNDSYTLHKILPNKVDPLVSLMMVEKVPDSTYEMIGGLDKQIKEIKEVIELPVKHP 172
           RVAL   + T+ + LP +VDPLV  M  E   D TY  IGGL +QI+E++EVIELP+ +P
Sbjct: 97  RVALDMTTLTIMRYLPREVDPLVYNMSHEDPGDVTYSAIGGLTEQIRELREVIELPLLNP 276

Query: 173 ELFEALGIAQPKGVLLYGPPGTGKTLLARAVAHHTDCTFIRVSGSELVQKFIGEGARMVR 232
           ELF  +GI  PKG LLYGPPGTGKTLLARAVA   D  F++V  S +V K+IGE AR++R
Sbjct: 277 ELFLRVGITPPKGCLLYGPPGTGKTLLARAVASQLDANFLKVVSSAIVDKYIGESARLIR 456

Query: 233 ELFVMAREHAPSIIFMDEIDSIGSSRLEGGSGGDSEVQRTMLELLNQLDGFEATKNIKVI 292
           E+F  AR+H P IIFMDEID+IG  R   G+  D E+QRT++ELLNQ+DGF++   +K+I
Sbjct: 457 EMFNYARDHQPCIIFMDEIDAIGGRRFSEGTSADREIQRTLMELLNQMDGFDSLGQVKMI 636

Query: 293 MATNRIDILDSALLRPGRIDRKIEFPPPNEEARLDILKIHSRKMNLTRGINLRKIAELMP 352
           MATNR D LD ALLRPGR+DRKIE P PNE+ARL+ILKIH+  +     I+   I +L  
Sbjct: 637 MATNRPDTLDPALLRPGRLDRKIEIPLPNEQARLEILKIHALIIAKHGEIDYEAIVKLSD 816

Query: 353 GASGAEVKGVCTEAGMYALRERRVHVTQEDFEMAVAKV 390
             +GA+++ VCTEAG++A+R  R +V QEDF  AV KV
Sbjct: 817 NFNGADLRNVCTEAGLFAIRAEREYVIQEDFMKAVRKV 930
>23766
          Length = 1463

 Score =  271 bits (692), Expect(2) = 1e-84,   Method: Compositional matrix adjust.
 Identities = 127/218 (58%), Positives = 166/218 (76%)
 Frame = +1

Query: 179 GIAQPKGVLLYGPPGTGKTLLARAVAHHTDCTFIRVSGSELVQKFIGEGARMVRELFVMA 238
           G   PKGV+LYGPPGTGKTLLA+AVA+ T  TF+RV GSEL+QK++G+G ++VRELF +A
Sbjct: 142 GNQAPKGVILYGPPGTGKTLLAKAVANQTSATFLRVVGSELIQKYLGDGPKLVRELFRVA 321

Query: 239 REHAPSIIFMDEIDSIGSSRLEGGSGGDSEVQRTMLELLNQLDGFEATKNIKVIMATNRI 298
            EHAPSI+F+DEID++G+ R E  SGG+ E+QRTMLELLNQLDGF++  ++KVIMATNRI
Sbjct: 322 EEHAPSIVFIDEIDAVGTKRYESNSGGEREIQRTMLELLNQLDGFDSRGDVKVIMATNRI 501

Query: 299 DILDSALLRPGRIDRKIEFPPPNEEARLDILKIHSRKMNLTRGINLRKIAELMPGASGAE 358
           + LD AL+RPGRIDRKIEFP P+E+ +  I  IH+ +M L   +N+          SGA+
Sbjct: 502 ETLDPALIRPGRIDRKIEFPLPDEKTKRRIFTIHTSRMTLAGDVNIDDYVMSKDDLSGAD 681

Query: 359 VKGVCTEAGMYALRERRVHVTQEDFEMAVAKVMQKDSE 396
           +K +CTEAG+ ALRERR+ V  EDF  A   V+ + +E
Sbjct: 682 IKAICTEAGLLALRERRMKVRNEDFAKAKENVLYRKNE 795

 Score = 60.5 bits (145), Expect(2) = 1e-84,   Method: Compositional matrix adjust.
 Identities = 29/53 (54%), Positives = 37/53 (69%), Gaps = 1/53 (1%)
 Frame = +2

Query: 133 PLVSLMM-VEKVPDSTYEMIGGLDKQIKEIKEVIELPVKHPELFEALGIAQPK 184
           P+V++M   EK P  TY  IGGLD QI+EIKE +ELP+ HPE +E +GI   K
Sbjct: 2   PMVTVMKGWEKAPQETYADIGGLDTQIQEIKESVELPLTHPEYYEEMGIKHQK 160
>01642
          Length = 1406

 Score =  285 bits (729), Expect = 2e-77,   Method: Compositional matrix adjust.
 Identities = 135/267 (50%), Positives = 185/267 (69%)
 Frame = -1

Query: 128  PNKVDPLVSLMMVEKVPDSTYEMIGGLDKQIKEIKEVIELPVKHPELFEALGIAQPKGVL 187
            P ++  +     + + P   Y  IGG+D Q +E++E +ELP+ H EL++ +GI  P+GVL
Sbjct: 1058 PQRLTAVSQCFKLMRSPT*XYSDIGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGVL 879

Query: 188  LYGPPGTGKTLLARAVAHHTDCTFIRVSGSELVQKFIGEGARMVRELFVMAREHAPSIIF 247
            +YGPPG GKT+LA+AVAHHT   FIRV GSE VQK++GEG RMVR++F +A+E+AP+IIF
Sbjct: 878  MYGPPGCGKTMLAKAVAHHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIF 699

Query: 248  MDEIDSIGSSRLEGGSGGDSEVQRTMLELLNQLDGFEATKNIKVIMATNRIDILDSALLR 307
            +DEID+I + R +  +G D EVQR +LELLNQ+DGF+ T N+KVIMATNR D LD ALLR
Sbjct: 698  IDEIDAIATKRFDAQTGADREVQRILLELLNQMDGFDQTVNVKVIMATNRADTLDPALLR 519

Query: 308  PGRIDRKIEFPPPNEEARLDILKIHSRKMNLTRGINLRKIAELMPGASGAEVKGVCTEAG 367
            PGR+DRKIEFP P+   +  I    + KMN++  ++L          SGA++  +C EAG
Sbjct: 518  PGRLDRKIEFPLPDRRQKRLIFSTITGKMNISEEVDLEDYVARPDKISGADINAICQEAG 339

Query: 368  MYALRERRVHVTQEDFEMAVAKVMQKD 394
            M A+RE R  V  +DFE      ++KD
Sbjct: 338  MQAVRENRYVVLAKDFEKGYKNNIKKD 258
>07247
          Length = 1753

 Score =  237 bits (605), Expect(2) = 2e-74,   Method: Compositional matrix adjust.
 Identities = 113/199 (56%), Positives = 146/199 (73%)
 Frame = -2

Query: 192  PGTGKTLLARAVAHHTDCTFIRVSGSELVQKFIGEGARMVRELFVMAREHAPSIIFMDEI 251
            PGTGKTLLARAVA   DC F++V  S +V K+IGE AR++RE+F  AR+H P IIFMDEI
Sbjct: 1407 PGTGKTLLARAVASQLDCNFLKVVSSAIVDKYIGESARLIREMFAFARDHEPCIIFMDEI 1228

Query: 252  DSIGSSRLEGGSGGDSEVQRTMLELLNQLDGFEATKNIKVIMATNRIDILDSALLRPGRI 311
            D+IG  R   G+  D E+QRT++ELLNQ+DGF+A   +K+IMATNR D LD ALLRPGR+
Sbjct: 1227 DAIGGRRFSEGTSADREIQRTLMELLNQMDGFDALGQVKMIMATNRPDTLDPALLRPGRL 1048

Query: 312  DRKIEFPPPNEEARLDILKIHSRKMNLTRGINLRKIAELMPGASGAEVKGVCTEAGMYAL 371
            DRKIE   PNE+ARL+ILKIH+  +     I+   + +L    +GA+++ VCTEAGM+A+
Sbjct: 1047 DRKIEISLPNEQARLEILKIHANPIAKHGEIDWEAVVKLSEDFNGADLRNVCTEAGMFAI 868

Query: 372  RERRVHVTQEDFEMAVAKV 390
            R  R +V +EDF  AV KV
Sbjct: 867  RAERDYVIEEDFMKAVRKV 811

 Score = 60.1 bits (144), Expect(2) = 2e-74,   Method: Compositional matrix adjust.
 Identities = 29/61 (47%), Positives = 41/61 (67%)
 Frame = -1

Query: 131  VDPLVSLMMVEKVPDSTYEMIGGLDKQIKEIKEVIELPVKHPELFEALGIAQPKGVLLYG 190
            +DPLV  M VE   D T+  IGGL +Q++E++EVIELP+ +PELF+ +GI + K      
Sbjct: 1588 MDPLVYNMSVEDPGDITFNQIGGLGEQVRELREVIELPLLNPELFQRVGITRLKAACCSD 1409

Query: 191  P 191
            P
Sbjct: 1408 P 1406
>02582
          Length = 1101

 Score =  177 bits (450), Expect = 5e-45,   Method: Compositional matrix adjust.
 Identities = 106/293 (36%), Positives = 165/293 (56%), Gaps = 34/293 (11%)
 Frame = +3

Query: 148 YEMIGGLDKQIKEIKEVIELPVKHPELFEALGIAQPKGVLLYGPPGTGKTLLARAVAHHT 207
           +  IGGLD    +I++ +E P+ +P+ F+ALG+   KGVLLYGPPG GKT LA+A A   
Sbjct: 138 WTDIGGLDLVKLQIRQAVEWPLLYPDTFQALGLPLTKGVLLYGPPGCGKTTLAQAAATAC 317

Query: 208 DCTFIRVSGSELVQKFIGEGARMVRELFVMAREHAPSIIFMDEIDSIGSSRLEGGSGGDS 267
             TF+ +S ++L   ++G+  + + E F  AR  APSI+F+DE+D+I   R +  S G  
Sbjct: 318 HVTFLSLSCAQLYSPYVGDAEKKISETFQKARALAPSILFLDEMDAIVGKRSD-SSLGSG 494

Query: 268 EVQRTMLELLNQLDGF-------------------------------EA-TKNIKVIMAT 295
             +R +  LLN++DG                                EA  +++ V+ AT
Sbjct: 495 VSERVLSALLNEMDGIGVRLDDKSDSREMEIEGSSDHTPQVRQHAVKEAHDRHVLVVAAT 674

Query: 296 NRIDILDSALLRPGRIDRKIEFPPPNEEARLDILKIHSRKMNLTRGINLRKIAELMPGAS 355
           NR D+LD ALLRPGR+DR I  PPP+ + RL    IH+RKM L + ++++++A+L  G +
Sbjct: 675 NRPDMLDPALLRPGRMDRLIYVPPPDVQGRLQSFTIHTRKMPLGKDVDVKQLADLTAGYT 854

Query: 356 GAEVKGVCTEAGMYALRERRVH--VTQEDFEMAVAKVMQKDSEKNMSIKKLWK 406
           GA++K +C E G+ AL+E      V Q+ F  A+       S  +  ++ ++K
Sbjct: 855 GADIKTLCNEVGLLALKESMSAECVNQDHFLNAIKTRKPSLSADSSEVETMYK 1013
>12235
          Length = 1749

 Score =  160 bits (404), Expect = 1e-39,   Method: Compositional matrix adjust.
 Identities = 80/183 (43%), Positives = 115/183 (62%), Gaps = 2/183 (1%)
 Frame = +1

Query: 211 FIRVSGSELVQKFIGEGARMVRELFVMAREHAPSIIFMDEIDSIGSSRLEGGSGGDSEVQ 270
           FI VSGSE ++ F+G G   VR++F  AR++AP I+F+DEID++G  R     GG SE +
Sbjct: 16  FITVSGSEFLEMFVGVGPSRVRDMFATARKNAPCILFVDEIDAVGRKRSGRNFGGQSEQE 195

Query: 271 RTMLELLNQLDGFEATKNIKVIMATNRIDILDSALLRPGRIDRKIEFPPPNEEARLDILK 330
            T+ +LL ++DGF     + V+ ATNR+DILD+ALLRPGR DR+I  P P+ + R  I K
Sbjct: 196 NTLNQLLVEMDGFNTQTGVVVLAATNRVDILDAALLRPGRFDRQIFVPLPDIKXRASIFK 375

Query: 331 IH--SRKMNLTRGINLRKIAELMPGASGAEVKGVCTEAGMYALRERRVHVTQEDFEMAVA 388
           +H    K  + +    RK+A L PG SGA++  VC EA + A R+    +    FE A+ 
Sbjct: 376 VHLDPLKTEVNKNDLARKMAALTPGFSGADIANVCNEAALIAARDLNTSIHMTHFEQAIE 555

Query: 389 KVM 391
           +V+
Sbjct: 556 RVV 564
>03022
          Length = 2255

 Score =  150 bits (379), Expect = 8e-37,   Method: Compositional matrix adjust.
 Identities = 89/248 (35%), Positives = 140/248 (56%), Gaps = 4/248 (1%)
 Frame = +2

Query: 130  KVDPLVSLMMVEKVPDSTYEMIGGLDKQIKEIKEVIELPVKHPELFEALGIAQPKGVLLY 189
            K  P         VP +T+E +G L     ++K+ I   +  PE+  A G+    G++L 
Sbjct: 1370 KAQPAAKREGFATVPTTTWEDVGALSNVRAQLKDSILCRIHDPEVSSAFGLPTNSGIILV 1549

Query: 190  GPPGTGKTLLARAVAHHTDCTFIRVSGSELVQKFIGEGARMVRELFVMAREHAPSIIFMD 249
            GPPG GKTL+A+A+A+     FI + G EL+ K++GE  R +RE F  A+  AP +IF D
Sbjct: 1550 GPPGCGKTLVAKAMANEAGLNFIYIKGPELLDKYVGESERNLREKFDKAQACAPCLIFFD 1729

Query: 250  EIDSIGSSRL--EGGSGGDSEVQRTMLELLNQLDGFEATKNIKVIMATNRIDILDSALLR 307
            E+D++ S+R   +G + G S       +LL  +DG      + V+ ATN I+ +D AL R
Sbjct: 1730 EMDTLCSNRQNNDGSNVGKSVTN----QLLALMDGCGERSQVYVMGATNIIENVDPALQR 1897

Query: 308  PGRIDRKIEFPPPNEEARLDILKIHSRKMNLTR--GINLRKIAELMPGASGAEVKGVCTE 365
            PGR DRKI    P+ + RLDIL+  ++  +  +    +++++A+   G SGA++K +  E
Sbjct: 1898 PGRFDRKIFIGLPDTDGRLDILRALTKGGSQRKLESCDMQQLAQDTEGFSGADLKHLVNE 2077

Query: 366  AGMYALRE 373
            A   AL+E
Sbjct: 2078 ASTIALKE 2101

 Score = 53.1 bits (126), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 30/116 (25%), Positives = 56/116 (48%), Gaps = 2/116 (1%)
 Frame = +1

Query: 142 KVPDSTYEMIGGLDKQIKEIKEVIE--LPVKHPELFEALGIAQPKGVLLYGPPGTGKTLL 199
            +P +T +  GG +K + E+    E  L   + +   A      +  LLYGP G+GK  L
Sbjct: 508 SIPTATLDDFGGSNKLLAELDSDFEEILYSDYCQYASACDQKACRRYLLYGPRGSGKRFL 687

Query: 200 ARAVAHHTDCTFIRVSGSELVQKFIGEGARMVRELFVMAREHAPSIIFMDEIDSIG 255
           A  +A       ++   + L+    G+  + VR+LF  A   AP ++++++I+ + 
Sbjct: 688 AECIAGQLKLPLLKPKINTLISGVSGDSEQRVRDLFDQAVSQAPCVLYLEDIECLA 855
>26408
          Length = 463

 Score =  123 bits (308), Expect = 2e-28,   Method: Compositional matrix adjust.
 Identities = 78/142 (54%), Positives = 87/142 (61%), Gaps = 4/142 (2%)
 Frame = +1

Query: 70  GSYVGEVVRAMDKKKVLVKVHPEGKFXXXXXXXXXXXXXTPN--CRVALRNDSYTLHKIL 127
           GSYVGEVV+ MDKKKVLVKVHPEGKF                  CR A R     LH   
Sbjct: 25  GSYVGEVVKPMDKKKVLVKVHPEGKFVVDFGQEY*YKRCYAQLPCRTAQRK----LHTTQ 192

Query: 128 PNKVDPLVSLMMVEKVPDSTYEMIGG--LDKQIKEIKEVIELPVKHPELFEALGIAQPKG 185
                   +  + +    + + +  G  L    + IKEVIELPVKHPELF+ALGIAQPKG
Sbjct: 193 DLAKQSGSASFVDDGRKSARFNIRNGWWLG*ANQRIKEVIELPVKHPELFDALGIAQPKG 372

Query: 186 VLLYGPPGTGKTLLARAVAHHT 207
           VLLYGPPGTGKTLLARAVAHHT
Sbjct: 373 VLLYGPPGTGKTLLARAVAHHT 438

 Score =  122 bits (306), Expect = 3e-28,   Method: Compositional matrix adjust.
 Identities = 62/107 (57%), Positives = 69/107 (64%)
 Frame = +2

Query: 109 TPNCRVALRNDSYTLHKILPNKVDPLVSLMMVEKVPDSTYEMIGGLDKQIKEIKEVIELP 168
           TPNCRVALRN+SYTLHKILPNKVDPLVSLMMVEKVPDSTYEM+GGLDKQIKE +     P
Sbjct: 143 TPNCRVALRNESYTLHKILPNKVDPLVSLMMVEKVPDSTYEMVGGLDKQIKESRR*SNCP 322

Query: 169 VKHPELFEALGIAQPKGVLLYGPPGTGKTLLARAVAHHTDCTFIRVS 215
              P       +   +       P   K  L   +    +CTFIRVS
Sbjct: 323 SSIPNCSMPWALLSQRVYCCTVRPVLAKRCLPVRLPITPECTFIRVS 463
>00810
          Length = 1431

 Score =  107 bits (267), Expect = 8e-24,   Method: Compositional matrix adjust.
 Identities = 72/223 (32%), Positives = 120/223 (53%), Gaps = 3/223 (1%)
 Frame = -3

Query: 154  LDKQIKEIKEVIELPVKHPELFEALGIAQP-KGVLLYGPPGTGKTLLARAVAHHTDCTFI 212
            L+  I+++KE + LP K  +LF    + QP KGVLL+GPPG GKT++A+A A      FI
Sbjct: 1429 LEDVIQDVKETVILPFKRADLFRHSSLLQPPKGVLLHGPPGCGKTMIAKATAKAAGARFI 1250

Query: 213  RVSGSELVQKFIGEGARMVRELFVMAREHAPSIIFMDEIDSIGSSRLEGGSGGDSEVQRT 272
             +  S LV K+ GE  +    +F +A +  P+IIF+DEIDS   SR        + ++  
Sbjct: 1249 NLQVSSLVDKWYGESQKRAEAVFSLAIKLQPTIIFIDEIDSFLRSRTSTDHEATAMIK-- 1076

Query: 273  MLELLNQLDGFEATKNIKVIM--ATNRIDILDSALLRPGRIDRKIEFPPPNEEARLDILK 330
              + ++  DG     + +V++  ATNR   +D+A+LR       I  P P +   +  L 
Sbjct: 1075 -TQFMSFWDGLMTDPDCRVMVMGATNRPQDVDAAILRRMPSMFHIGLPGPAQRRSIFNLI 899

Query: 331  IHSRKMNLTRGINLRKIAELMPGASGAEVKGVCTEAGMYALRE 373
            +   +++    +N  ++AE+  G SG++++ VC  A +  + E
Sbjct: 898  LSKERID---ALNYDELAEMTDGFSGSDIREVCRAAAVATVHE 779
>20270
          Length = 542

 Score =  103 bits (256), Expect = 2e-22,   Method: Compositional matrix adjust.
 Identities = 58/126 (46%), Positives = 80/126 (63%), Gaps = 2/126 (1%)
 Frame = -3

Query: 184 KGVLLYGPPGTGKTLLARAVAHH-TDCTFIRVSGSELVQKFIGEGARMVRELFVMAREHA 242
           +G+LLYGPPGTGK+ LA+AVA    + TF  VS S+LV K++GE  ++V+ LF +ARE+ 
Sbjct: 378 RGILLYGPPGTGKSYLAKAVATEANNSTFFSVSSSDLVSKWLGESEKLVKTLFQLARENQ 199

Query: 243 PSIIFMDEIDSIGSSRLEGGSGGDSEVQRTMLELLNQLDGF-EATKNIKVIMATNRIDIL 301
           PSIIF+DE+D++  SR E  S      +R   E L Q+ G       + V+ ATN    L
Sbjct: 198 PSIIFIDEVDALCGSRSENES---ESARRIKTEFLVQMQGVGNDNTGVLVLGATNIPWTL 28

Query: 302 DSALLR 307
           DSA+ R
Sbjct: 27  DSAIRR 10
>38672
          Length = 730

 Score = 82.8 bits (203), Expect(2) = 3e-21,   Method: Compositional matrix adjust.
 Identities = 46/140 (32%), Positives = 79/140 (56%), Gaps = 18/140 (12%)
 Frame = -3

Query: 268 EVQRTML-ELLNQLDGFEATKNIKVIMATNRIDILDSALLRPGRIDRKIEFPPPNEEARL 326
           EV+R ++ +LL  +DG +   ++ V+ ATNR + +D+AL R GR DR+++   P+   RL
Sbjct: 596 EVERRIVSQLLTLMDGLKQRSHVIVMAATNRPNSVDAALRRFGRFDREVDIGIPDATGRL 417

Query: 327 DILKIHSRKMNLTRGINLRKIAELMPGASGAEVKGVCTEAGMYALRER------------ 374
           +IL+IH++ M L   ++L ++A    G  GA+V  +C+EA +  +RE+            
Sbjct: 416 EILRIHTKNMKLADDVDLEQVASETHGHVGADVAALCSEAALQQIREKMDLIDLEDDTID 237

Query: 375 -----RVHVTQEDFEMAVAK 389
                 + VT +DF  A+ K
Sbjct: 236 AEVLDSLAVTMDDFRWALGK 177

 Score = 36.6 bits (83), Expect(2) = 3e-21,   Method: Compositional matrix adjust.
 Identities = 16/40 (40%), Positives = 26/40 (65%)
 Frame = -1

Query: 219 LVQKFIGEGARMVRELFVMAREHAPSIIFMDEIDSIGSSR 258
           ++ K  GE    +R+ F  A ++AP+IIF+DE+D+I   R
Sbjct: 730 IMSKLAGESESNLRKAFEEAEKNAPAIIFIDELDAIAPKR 611

 Score = 48.1 bits (113), Expect = 6e-06,   Method: Compositional matrix adjust.
 Identities = 20/47 (42%), Positives = 33/47 (70%)
 Frame = -3

Query: 142 KVPDSTYEMIGGLDKQIKEIKEVIELPVKHPELFEALGIAQPKGVLL 188
           +VP+ ++E +GGL+   KE++E+++ PV+HPE F   G+   KGVL 
Sbjct: 143 EVPNVSWEDVGGLENVKKELQELVQYPVEHPEKFLKFGMTPSKGVLF 3
>25671
          Length = 441

 Score = 84.0 bits (206), Expect = 1e-16,   Method: Compositional matrix adjust.
 Identities = 54/111 (48%), Positives = 65/111 (58%), Gaps = 8/111 (7%)
 Frame = +2

Query: 194 TGKTLLARAVAHHTDCTFIRVSGSELVQKFIGEGARMVRELFVMAREHAPSIIFMDEIDS 253
           TGKT+LA+AVA     TF  VS S L  K+ GE  ++VR LF MA  +APS IF+DEIDS
Sbjct: 2   TGKTMLAKAVATECGTTFFNVSTSSLANKYRGESEKLVRLLFEMAHFYAPSTIFIDEIDS 181

Query: 254 IGSSRLEGGSGGDSE---VQRTMLELLNQLDGFEAT-----KNIKVIMATN 296
           I S R     G DSE    +R   ELL Q+DG   T     K + V+ ATN
Sbjct: 182 ICSKR-----GSDSEHEASRRVKSELLVQMDGVGVTNDDPSKAVMVLAATN 319
>02194
          Length = 1891

 Score = 67.0 bits (162), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 52/151 (34%), Positives = 72/151 (47%), Gaps = 8/151 (5%)
 Frame = -1

Query: 172  PELFEALGIAQPKGVLLYGPPGTGKTLLARAVAHHTDCTFIRVSGSELVQKFIGEGARMV 231
            P  +   GI   +G LLYGPPG GK+    A+A   D     ++ SE      G     +
Sbjct: 1531 PRWYMDRGIPYRRGYLLYGPPGCGKSSYIMALAGALDYNICVLNLSE-----KGLSDDRL 1367

Query: 232  RELFVMAREHAPSIIFMDEIDSIGSSR--------LEGGSGGDSEVQRTMLELLNQLDGF 283
              L  +A E   SII ++++D+   SR        +  G G     + T   LLN LDG 
Sbjct: 1366 NHLLTVAPEQ--SIILLEDVDAAFLSRDLSKENPAMYQGMG-----RLTFSGLLNALDGV 1208

Query: 284  EATKNIKVIMATNRIDILDSALLRPGRIDRK 314
             + +   V M TN +D LD AL+RPGR+D K
Sbjct: 1207 ASAEARIVFMTTNYLDRLDPALIRPGRVDMK 1115
>17843
          Length = 772

 Score = 62.4 bits (150), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 46/173 (26%), Positives = 81/173 (46%), Gaps = 15/173 (8%)
 Frame = +1

Query: 180 IAQPKGVLLYGPPGTGKTLLARAVA--------HHTDC-TFIRVSGSELVQKFIGEGARM 230
           I+  + +LL+GPPGTGKT L +A+A        H   C   + ++   L  K+  E  ++
Sbjct: 175 ISWNRVILLHGPPGTGKTTLCKALAHKLCIRLSHRFSCGQLVEINSHSLFSKWFSESGKL 354

Query: 231 VRELF-----VMAREHAPSIIFMDEIDSIGSSRLEGGSGGD-SEVQRTMLELLNQLDGFE 284
           V ++F      M        + +DE++S+ ++R    +G + S+  R +  +L Q+D  +
Sbjct: 355 VTKMFQRLHDYMVDPELLVCVLIDEVESLTAARKSCLNGNEPSDAIRVVNAVLTQIDQLK 534

Query: 285 ATKNIKVIMATNRIDILDSALLRPGRIDRKIEFPPPNEEARLDILKIHSRKMN 337
              N  ++  +N    +D A +   R D K    PP   A   I KI+   +N
Sbjct: 535 KFANCLILTTSNITGAIDLAFV--DRADIKQYIGPPTPPA---IYKIYLSCLN 678
>26887
          Length = 410

 Score = 51.2 bits (121), Expect = 7e-07,   Method: Compositional matrix adjust.
 Identities = 23/38 (60%), Positives = 30/38 (78%)
 Frame = -3

Query: 258 RLEGGSGGDSEVQRTMLELLNQLDGFEATKNIKVIMAT 295
           R E  SGG+ E+QRTMLELLNQLDGF++  ++KV + T
Sbjct: 168 RYESNSGGEREIQRTMLELLNQLDGFDSRGDVKVHLXT 55
>06766
          Length = 976

 Score = 44.7 bits (104), Expect = 6e-05,   Method: Compositional matrix adjust.
 Identities = 23/64 (35%), Positives = 40/64 (62%)
 Frame = +2

Query: 310 RIDRKIEFPPPNEEARLDILKIHSRKMNLTRGINLRKIAELMPGASGAEVKGVCTEAGMY 369
           R+D+ I  P P++++R  ILK + RK  L + ++L  IA++  G SGA++  +C  A   
Sbjct: 2   RLDQLIYIPLPDDKSREAILKANLRKSPLAKEVDLTYIAKVTQGFSGADLTEICQRACKL 181

Query: 370 ALRE 373
           A+R+
Sbjct: 182 AIRQ 193
>19561
          Length = 474

 Score = 43.5 bits (101), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 30/94 (31%), Positives = 43/94 (45%), Gaps = 12/94 (12%)
 Frame = -1

Query: 184 KGVLLYGPPGTGKTLLARAVAHHTDCTFIRVSGSE--LVQKFIGEGARMVRELFVMAREH 241
           K  LL GPPG GKT LA  VA H     + ++ S+   V+ F  +     +   VM  + 
Sbjct: 378 KVALLCGPPGLGKTTLAHIVAKHAGYNVVEMNASDDRSVEVFSNKIEAATQMRAVMGADP 199

Query: 242 APSIIFMDEIDSIGSS----------RLEGGSGG 265
            P+ + +DEID    +          R E G+GG
Sbjct: 198 RPNCLIIDEIDGAPQAAVNVLLNILKRPEAGAGG 97
>14413
          Length = 826

 Score = 43.5 bits (101), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 33/132 (25%), Positives = 57/132 (43%), Gaps = 10/132 (7%)
 Frame = +2

Query: 199 LARAVAHHTDCTF-----IRVSGSELVQKFIGEGARMVRELFVMAREHAPS-----IIFM 248
           LA  +A  T  +F     + ++   L  K+  E  ++V  LF    E A        + +
Sbjct: 23  LAEKLAIRTQNSFAYTHLVEINSHSLFSKWFSESGKLVARLFGKIGELATDKNNLVCVLI 202

Query: 249 DEIDSIGSSRLEGGSGGDSEVQRTMLELLNQLDGFEATKNIKVIMATNRIDILDSALLRP 308
           DE++S+  +R    S    +  R +  +L QLD  +A  N+ ++  +N    +D A L  
Sbjct: 203 DEVESLAYARSAMSSNEPRDAMRVVNAVLTQLDEIKACPNVLILATSNLAQSIDLAFLDR 382

Query: 309 GRIDRKIEFPPP 320
             I + I  P P
Sbjct: 383 ADIRQFIGLPDP 418
>01279
          Length = 2183

 Score = 34.3 bits (77), Expect = 0.086,   Method: Compositional matrix adjust.
 Identities = 18/38 (47%), Positives = 23/38 (60%), Gaps = 2/38 (5%)
 Frame = -3

Query: 184  KGVLLYGPPGTGKTLLARAVAHH--TDCTFIRVSGSEL 219
            + VLL GPPGTGKT +A A+A        F  + GSE+
Sbjct: 1914 RAVLLAGPPGTGKTAIALAIAQELGNKVPFCPMVGSEV 1801
>37695
          Length = 156

 Score = 33.9 bits (76), Expect = 0.12,   Method: Composition-based stats.
 Identities = 15/25 (60%), Positives = 19/25 (76%)
 Frame = +3

Query: 363 CTEAGMYALRERRVHVTQEDFEMAV 387
           CTEAGM+A+R RR   T++DF  AV
Sbjct: 9   CTEAGMFAIRARRKMATEKDFLDAV 83
>05247
          Length = 375

 Score = 32.0 bits (71), Expect = 0.47,   Method: Composition-based stats.
 Identities = 13/26 (50%), Positives = 17/26 (65%)
 Frame = +2

Query: 310 RIDRKIEFPPPNEEARLDILKIHSRK 335
           R+DR I  PPP+ + RL    IH+RK
Sbjct: 2   RMDRLIYVPPPDVQGRLQSFTIHTRK 79
>02744
          Length = 3030

 Score = 30.8 bits (68), Expect = 0.94,   Method: Compositional matrix adjust.
 Identities = 20/56 (35%), Positives = 30/56 (53%), Gaps = 3/56 (5%)
 Frame = +1

Query: 190  GPPGTGKTLLARAVAHHTD---CTFIRVSGSELVQKFIGEGARMVRELFVMAREHA 242
            G  G G+   +  + HHT     TF  +   ELVQ+ + E   +V+ LF +A+EHA
Sbjct: 2767 GAEGRGRDSQSHCLGHHTTPRLLTFDNLLFEELVQQKVAEVRIIVKGLFDVAQEHA 2934
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|9790051|ref|NP_062677.1| phosphofructokinase,
platelet [Mus musculus]
         (784 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

03664                                                                 545   e-155
05449                                                                 350   2e-96
18160                                                                  32   0.67 
25936                                                                  29   6.1  
>03664
          Length = 1237

 Score =  545 bits (1404), Expect = e-155,   Method: Compositional matrix adjust.
 Identities = 260/375 (69%), Positives = 304/375 (81%)
 Frame = +3

Query: 23  GKAIGVLTSGGDAQGMNAAVRAVVRMGIYTGAKVYFIYEGYQGLVDGGSNIVEAKWDCVS 82
           G  IGV TSGGD+QGMN AVRAVVRMG Y G KVY I EGYQG+VDGG NI EA W  VS
Sbjct: 102 GNTIGVFTSGGDSQGMNGAVRAVVRMGFYLGCKVYVIREGYQGMVDGGENIEEATWASVS 281

Query: 83  SILQVGGTIIGSARCKAFRSREGRLKAACNLARLGITNLCVIGGDGSLTGANLFRKEWSG 142
            ILQ+GGT+IGSAR   FR REGRLKAA NL + GITNL VIGGDGSLTGA+LFR+EW+ 
Sbjct: 282 GILQLGGTVIGSARSADFRQREGRLKAAANLVKRGITNLVVIGGDGSLTGADLFRREWAS 461

Query: 143 LLEELARNGDIDNDTVQKYSYLNVVGMVGSIDNDFCGTDMTIGTDSALHRIIEVVDAIMT 202
           LL EL   G++  D + +  +LN+VGMVGSIDNDFCGTDMTIGTDSALHRIIE VDAI T
Sbjct: 462 LLTELKEKGELTGDEMVRCQHLNIVGMVGSIDNDFCGTDMTIGTDSALHRIIEAVDAIST 641

Query: 203 TAQSHQRTFVLEVMGRHCGYLALVSALTCGADWVFLPESPPEEDWEENMCLKLSENRARK 262
           TA SHQR FV+EVMGRHCGYLALV+AL C ADWVF+PE PPE DW+  +C KL   R   
Sbjct: 642 TAISHQRAFVMEVMGRHCGYLALVAALACEADWVFIPEWPPEGDWKTTLCNKLLSERKLG 821

Query: 263 KRLNIIIVSEGAIDMQNKPITSEKIKELVVKNLGFDTRVTILGHVQRGGTPSAFDRILAS 322
           +RLNII+V+EGAID +   ITS+++K+L+   L +DTRVT+LGHVQRGG+PSAFDRIL S
Sbjct: 822 QRLNIILVAEGAIDREGNSITSDQVKDLLTNELKYDTRVTVLGHVQRGGSPSAFDRILGS 1001

Query: 323 RMGVEAVIALLEATPETPACVVSLRGNQAVRLPLMECVQMTQDVQKAMDERRFKEAVKLR 382
           RMG EAV+AL++ATP+TPACVVSL GNQ VR+PLMECV  T+DVQKAMD + F+EAV+LR
Sbjct: 1002RMGAEAVLALMDATPDTPACVVSLEGNQTVRVPLMECVSRTKDVQKAMDMKNFEEAVQLR 1181

Query: 383 GRRFEGNLNTYKRLA 397
           G+ F+ NL TY+ L+
Sbjct: 1182GKSFQNNLTTYRMLS 1226

 Score =  112 bits (281), Expect = 4e-25,   Method: Compositional matrix adjust.
 Identities = 88/309 (28%), Positives = 146/309 (47%), Gaps = 26/309 (8%)
 Frame = +3

Query: 411 NVAVINVGAPAAGMNAAVRSAVRVGIADGHKMFAIYDGFEGFANG--QIKEIGWADVGGW 468
            + V   G  + GMN AVR+ VR+G   G K++ I +G++G  +G   I+E  WA V G 
Sbjct: 108 TIGVFTSGGDSQGMNGAVRAVVRMGFYLGCKVYVIREGYQGMVDGGENIEEATWASVSGI 287

Query: 469 TGQGGSILGTKRTLPGKYLE---KIAEQMHSHSINALLIIXXXXXXXXX--------XXX 517
              GG+++G+ R+   +  E   K A  +    I  L++I                    
Sbjct: 288 LQLGGTVIGSARSADFRQREGRLKAAANLVKRGITNLVVIGGDGSLTGADLFRREWASLL 467

Query: 518 XXXXXKHEAFCVPMVM--------VPATVSNNVPGSDFSIGADTALNTITDTCDRIKQSA 569
                K E     MV         +  ++ N+  G+D +IG D+AL+ I +  D I  +A
Sbjct: 468 TELKEKGELTGDEMVRCQHLNIVGMVGSIDNDFCGTDMTIGTDSALHRIIEAVDAISTTA 647

Query: 570 SGTKRRVFIIETMGGYCGYXXXXXXXXXXXXXXYIFEEPFDIGDLQSNVVH-LTEKMKTS 628
             + +R F++E MG +CGY              +I E P + GD ++ + + L  + K  
Sbjct: 648 I-SHQRAFVMEVMGRHCGYLALVAALACEADWVFIPEWPPE-GDWKTTLCNKLLSERKLG 821

Query: 629 IQRGLVLRNESC----SVNYTTDFIYQLYSEEGKGVFDCRKNVLGHMQQGGAPSPFDRNF 684
            +  ++L  E        + T+D +  L + E K  +D R  VLGH+Q+GG+PS FDR  
Sbjct: 822 QRLNIILVAEGAIDREGNSITSDQVKDLLTNELK--YDTRVTVLGHVQRGGSPSAFDRIL 995

Query: 685 GTKISAKAM 693
           G+++ A+A+
Sbjct: 996 GSRMGAEAV 1022
>05449
          Length = 724

 Score =  350 bits (897), Expect = 2e-96,   Method: Compositional matrix adjust.
 Identities = 164/237 (69%), Positives = 196/237 (82%), Gaps = 5/237 (2%)
 Frame = +3

Query: 166 VVGMVGSIDNDFCGTDMTIGTDSALHRIIEVVDAIMTTAQSHQRTFVLEVMGRHCGYLAL 225
           +VGMVGSIDNDFCGTDMTIGTDSALHRIIE VDAI TTA SHQR FV+EVMGRHCGYLAL
Sbjct: 3   IVGMVGSIDNDFCGTDMTIGTDSALHRIIEAVDAISTTAISHQRAFVMEVMGRHCGYLAL 182

Query: 226 VSALTCGADWVFLPESPPEEDWEENMCLKLS-----ENRARKKRLNIIIVSEGAIDMQNK 280
           V+AL C ADWVF+PE PPE DW+  +C KL      + R   +RLNII+V+EGAID +  
Sbjct: 183 VAALACEADWVFIPEWPPEGDWKTTLCNKLLSSVALQERKLGQRLNIILVAEGAIDREGN 362

Query: 281 PITSEKIKELVVKNLGFDTRVTILGHVQRGGTPSAFDRILASRMGVEAVIALLEATPETP 340
            ITS+++K+L+   L +DTRVT+LGHVQRGG+PSAFDRIL SRMG EAV+AL++ATP+TP
Sbjct: 363 SITSDQVKDLLTNELKYDTRVTVLGHVQRGGSPSAFDRILGSRMGAEAVLALMDATPDTP 542

Query: 341 ACVVSLRGNQAVRLPLMECVQMTQDVQKAMDERRFKEAVKLRGRRFEGNLNTYKRLA 397
           ACVVSL GNQ VR+PLMECV  T+DVQKAMD + F+EAV+LRG+ F+ NL TY+ L+
Sbjct: 543 ACVVSLEGNQTVRVPLMECVSRTKDVQKAMDMKNFEEAVQLRGKSFQNNLTTYRMLS 713

 Score = 78.6 bits (192), Expect = 1e-14,   Method: Compositional matrix adjust.
 Identities = 53/168 (31%), Positives = 89/168 (52%), Gaps = 11/168 (6%)
 Frame = +3

Query: 537 TVSNNVPGSDFSIGADTALNTITDTCDRIKQSASGTKRRVFIIETMGGYCGYXXXXXXXX 596
           ++ N+  G+D +IG D+AL+ I +  D I  +A  + +R F++E MG +CGY        
Sbjct: 21  SIDNDFCGTDMTIGTDSALHRIIEAVDAISTTAI-SHQRAFVMEVMGRHCGYLALVAALA 197

Query: 597 XXXXXXYIFEEPFDIGDLQSNV-------VHLTEKMKTSIQRGLVLRNESC----SVNYT 645
                 +I E P + GD ++ +       V L E+ K   +  ++L  E        + T
Sbjct: 198 CEADWVFIPEWPPE-GDWKTTLCNKLLSSVALQER-KLGQRLNIILVAEGAIDREGNSIT 371

Query: 646 TDFIYQLYSEEGKGVFDCRKNVLGHMQQGGAPSPFDRNFGTKISAKAM 693
           +D +  L + E K  +D R  VLGH+Q+GG+PS FDR  G+++ A+A+
Sbjct: 372 SDQVKDLLTNELK--YDTRVTVLGHVQRGGSPSAFDRILGSRMGAEAV 509
>18160
          Length = 1010

 Score = 32.3 bits (72), Expect = 0.67,   Method: Compositional matrix adjust.
 Identities = 16/74 (21%), Positives = 35/74 (47%), Gaps = 2/74 (2%)
 Frame = +2

Query: 211 FVLEVMGRHCGYLALVSALTCGADWVFLPESPPEEDWEEN--MCLKLSENRARKKRLNII 268
           F+L+ M ++C +L+ ++AL       F+P  P    ++ +    + +   R R +   + 
Sbjct: 50  FILKFMNKYCAHLSFIAALP------FMPSQPQTGSYQGSAAYIVNMRHTRDRSRSTGLH 211

Query: 269 IVSEGAIDMQNKPI 282
           +    +I  Q +PI
Sbjct: 212 VSPSHSILTQGQPI 253
>25936
          Length = 459

 Score = 29.3 bits (64), Expect = 6.1,   Method: Composition-based stats.
 Identities = 14/30 (46%), Positives = 19/30 (63%)
 Frame = +2

Query: 459 EIGWADVGGWTGQGGSILGTKRTLPGKYLE 488
           E+GW+DVGG  G   S++ T +  P KY E
Sbjct: 329 ELGWSDVGGLEGVKSSLIETLQ-WPSKYPE 415
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|176865892|ref|NP_038534.2| eukaryotic translation
initiation factor 4A2 isoform a [Mus musculus]
         (407 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

01062                                                                 542   e-154
09316                                                                 232   3e-61
19640                                                                 145   3e-47
00621                                                                 181   5e-46
07310                                                                 167   6e-42
02498                                                                 124   8e-29
09327                                                                 119   2e-27
00739                                                                 117   1e-26
02054                                                                  81   1e-26
01517                                                                 116   2e-26
04883                                                                 101   6e-22
00162                                                                 101   7e-22
31899                                                                  94   7e-20
11160                                                                  75   1e-17
22006                                                                  87   1e-17
14337                                                                  85   6e-17
19525                                                                  83   2e-16
08036                                                                  61   1e-14
34295                                                                  73   3e-13
00617                                                                  70   1e-12
33025                                                                  62   4e-10
19172                                                                  61   6e-10
30136                                                                  59   4e-09
17708                                                                  59   5e-09
12995                                                                  58   9e-09
17544                                                                  54   2e-07
10649                                                                  53   3e-07
19151                                                                  52   6e-07
11624                                                                  49   4e-06
39583                                                                  46   2e-05
31781                                                                  43   3e-04
12121                                                                  37   0.021
31220                                                                  34   0.082
14329                                                                  34   0.11 
33083                                                                  32   0.49 
10351                                                                  31   0.94 
06438                                                                  31   1.0  
>01062
          Length = 2138

 Score =  542 bits (1396), Expect = e-154,   Method: Compositional matrix adjust.
 Identities = 259/378 (68%), Positives = 313/378 (82%)
 Frame = -3

Query: 30   EIVDNFDDMNLKESLLRGIYAYGFEKPSAIQQRAIIPCIKGYDVIAQAQSGTGKTATFAI 89
            E+   FD+M ++E LLRGIYAYGFEKPSAIQQRA+ P +KG DVIAQAQSGTGKTATF+I
Sbjct: 2088 EVTPTFDNMGIREELLRGIYAYGFEKPSAIQQRAVKPIVKGRDVIAQAQSGTGKTATFSI 1909

Query: 90   SILQQLEIEFKETQALVLAPTRELAQQIQKVILALGDYMGATCHACIGGTNVRNEMQKLQ 149
            S+LQ L+I+ +ETQAL+L+PTRELA QIQKV+LALGDYM   CH+CIGGTN+  +++KL 
Sbjct: 1908 SVLQCLDIQLRETQALILSPTRELATQIQKVMLALGDYMNVQCHSCIGGTNIGEDIRKLD 1729

Query: 150  AEAPHIVVGTPGRVFDMLNRRYLSPKWIKMFVLDEADEMLSRGFKDQIYEIFQKLNTSIQ 209
                HIV GTPGRVFDM+ RR L  + IKM +LDEADEML++GFK+QIY++++ L  + Q
Sbjct: 1728 Y-GQHIVSGTPGRVFDMIKRRNLRTRSIKMMILDEADEMLNKGFKEQIYDVYRYLPPATQ 1552

Query: 210  VVLLSATMPTDVLEVTKKFMRDPIRILVKKEELTLEGIKQFYINVEREEWKLDTLCDLYE 269
            V+L+SAT+P ++LE+T KFM DPIRILVK++ELTLEGIKQF++ VEREEWK DTLCDLY+
Sbjct: 1551 VILISATLPHEILEMTNKFMTDPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYD 1372

Query: 270  TLTITQAVIFLNTRRKVDWLTEKMHARDFTVSALHGDMDQKERDVIMREFRSGSSRVLIT 329
            TLTITQAVIF NT+RKVDWLTEKM   +FTVS++HGDM QKER+ IM+ FR+G SRVLIT
Sbjct: 1371 TLTITQAVIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKEREAIMKVFRAGDSRVLIT 1192

Query: 330  TDLLARGIDVQQVSLVINYDLPTNRENYIHXXXXXXXXXXXXVAINFVTEEDKRILRDIE 389
            TD+ ARGIDVQQVSLVINYDLP NRE YIH            VAINFV  +D RILRDIE
Sbjct: 1191 TDVWARGIDVQQVSLVINYDLPNNRELYIHRIGRSGRFGRKGVAINFVKNDDIRILRDIE 1012

Query: 390  TFYNTTVEEMPMNVADLI 407
             +Y+T ++EMPMNVADLI
Sbjct: 1011 QYYSTQIDEMPMNVADLI 958
>09316
          Length = 2312

 Score =  232 bits (591), Expect = 3e-61,   Method: Compositional matrix adjust.
 Identities = 135/370 (36%), Positives = 208/370 (56%), Gaps = 4/370 (1%)
 Frame = +2

Query: 35   FDDMNLKESLLRGIYAYGFEKPSAIQQRAIIPCIKGYDVIAQAQSGTGKTATFAISILQQ 94
            F D  LK  LLR I   GFE PS +Q   I   I   DV+ QA+SG GKTA F ++ LQQ
Sbjct: 851  FRDFLLKPELLRAIIDCGFEHPSEVQHECIPQAILSMDVLCQAKSGMGKTAVFVLATLQQ 1030

Query: 95   LEIEFKETQALVLAPTRELAQQIQKVILALGDYMGATCHAC-IGGTNVRNEMQKLQAEAP 153
            LE    +   LV+A TRELA QI K       YM     A   GG +V+ + + L    P
Sbjct: 1031 LEPVDGQVSVLVMAHTRELAFQISKEYERFSKYMNNVKIAVFFGGMSVKKDEEVLSKNCP 1210

Query: 154  HIVVGTPGRVFDMLNRRYLSPKWIKMFVLDEADEMLSR-GFKDQIYEIFQKLNTSIQVVL 212
            HIVVGTPGR+  +     L+ K IK F+LDE D+ML+    +  + EIF+      QV++
Sbjct: 1211 HIVVGTPGRLHALAKANNLNLKKIKHFILDECDKMLADLDMRRDVQEIFRLTPHEKQVMM 1390

Query: 213  LSATMPTDVLEVTKKFMRDPIRILVKKE-ELTLEGIKQFYINVEREEWKLDTLCDLYETL 271
             SAT+  ++  + KKFM+DP+ + V  + +LTL G++Q Y  ++  E K   L +L + L
Sbjct: 1391 FSATLSKEIRPICKKFMQDPMEVYVDDDSKLTLHGLQQHYCKLKDNE-KNRKLFELLDVL 1567

Query: 272  TITQAVIFLNTRRKVDWLTEKMHARDFTVSALHGDMDQKERDVIMREFRSGSSRVLITTD 331
               Q +IF+ +  +   L++ +  ++F   A+H  M Q+ER    ++F+    R+L+ T+
Sbjct: 1568 EFNQVIIFVKSVPRCMALSQLLLEQNFPAIAIHRQMTQEERLSRYQQFKDFQKRILVATN 1747

Query: 332  LLARGIDVQQVSLVINYDLPTNRENYIHXXXXXXXXXXXXVAINFVTEE-DKRILRDIET 390
            L  RG+D+++V++V NYD+P + + Y+H            +AI FV++E D +IL D++ 
Sbjct: 1748 LFGRGMDIERVNIVFNYDMPEDSDTYLHRVARAGRFGTKGLAITFVSDENDAKILNDVQE 1927

Query: 391  FYNTTVEEMP 400
             +   + E+P
Sbjct: 1928 RFEVNITELP 1957
>19640
          Length = 456

 Score =  145 bits (365), Expect(2) = 3e-47,   Method: Compositional matrix adjust.
 Identities = 66/82 (80%), Positives = 78/82 (95%)
 Frame = -1

Query: 278 IFLNTRRKVDWLTEKMHARDFTVSALHGDMDQKERDVIMREFRSGSSRVLITTDLLARGI 337
           IF NTRRKVD LT++M + +FTVSA+HGDM+Q++R+VIM++FRSGSSRVLITTDLLARGI
Sbjct: 456 IFCNTRRKVDQLTQEMSSHNFTVSAMHGDMEQRDREVIMKQFRSGSSRVLITTDLLARGI 277

Query: 338 DVQQVSLVINYDLPTNRENYIH 359
           DVQQVSLVINYDLP+NRENYIH
Sbjct: 276 DVQQVSLVINYDLPSNRENYIH 211

 Score = 61.2 bits (147), Expect(2) = 3e-47,   Method: Compositional matrix adjust.
 Identities = 26/36 (72%), Positives = 34/36 (94%)
 Frame = -3

Query: 372 VAINFVTEEDKRILRDIETFYNTTVEEMPMNVADLI 407
           VAINF+T++D+RIL+DIE FY+TT+EEMP N+ADLI
Sbjct: 175 VAINFITDDDRRILKDIEQFYHTTIEEMPANIADLI 68
>00621
          Length = 2263

 Score =  181 bits (459), Expect = 5e-46,   Method: Compositional matrix adjust.
 Identities = 116/407 (28%), Positives = 203/407 (49%), Gaps = 36/407 (8%)
 Frame = +1

Query: 35  FDDMNLKESLLRGIYAYGFEKPSAIQQRAIIPCIKGYDVIAQAQSGTGKTATFAISIL-- 92
           + + +L   ++  I   G+++P+ IQ +AI   ++  D+I  A++G+GKTA F I +L  
Sbjct: 259 WKESDLGADIMEVIDRVGYKEPTPIQMQAIPIGLQNRDIIGVAETGSGKTAAFLIPLLVW 438

Query: 93  -------QQLEIEFKETQALVLAPTRELAQQIQKVILALGDYMGATCHACIGGTNVRNEM 145
                  ++LE   +   A++LAPTRELAQQI++     G+ +G    + IGG +   + 
Sbjct: 439 IQSLPKIERLEDADQGPYAVILAPTRELAQQIEEETRKFGEGLGIRVVSVIGGISREEQG 618

Query: 146 QKLQAEAPHIVVGTPGRVFDMLNRRYLSPKWIKMFVLDEADEMLSRGFKDQIYEIFQKLN 205
            KLQ +   +V+ TPGR+ D+L  RYL        V+DEAD M++ GF+ ++ +I   L 
Sbjct: 619 FKLQ-QGCEVVIATPGRMIDVLENRYLVLNQCTYVVMDEADRMINMGFEPEVRKILDYLP 795

Query: 206 TS-------------------------IQVVLLSATMPTDVLEVTKKFMRDPIRILVKKE 240
            S                          Q V+ +ATMP  V  + + F+R P  + +   
Sbjct: 796 VSNQKPDNDDAEDDLKMLQNFKSKHKYRQTVMFTATMPPQVERLARTFLRRPTVVYIGNV 975

Query: 241 ELTLEGIKQF-YINVEREEWKLDTLCDLYETLTITQAVIFLNTRRKVDWLTEKMHARDFT 299
              +E ++Q  Y+  E E+ K   L ++         +IF+N ++  D L + +    F 
Sbjct: 976 GKPVERVEQIVYMLTESEKRK--KLIEVLNAGVDPPIIIFVNQKKGADVLAKSLEKMGFN 1149

Query: 300 VSALHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIH 359
            + LHG   Q++R+  +   + G+  +++ TD+  RGID++ VSLV+NYD+    E+Y H
Sbjct: 1150ATTLHGGKGQEQREYALASLKGGAKDIMVATDVAGRGIDIKDVSLVLNYDMARTIEDYTH 1329

Query: 360 XXXXXXXXXXXXVAINFVTEEDKRILRDIETF-YNTTVEEMPMNVAD 405
                        +I F+T+ED  +  D++    ++ V   P  +A+
Sbjct: 1330RIGRTGRAGKEGTSITFLTKEDSMVFYDLKQLMLSSPVSTCPPELAN 1470
>07310
          Length = 712

 Score =  167 bits (424), Expect = 6e-42,   Method: Compositional matrix adjust.
 Identities = 87/239 (36%), Positives = 141/239 (58%)
 Frame = +2

Query: 162 RVFDMLNRRYLSPKWIKMFVLDEADEMLSRGFKDQIYEIFQKLNTSIQVVLLSATMPTDV 221
           R+ D++N+R + P    + VLDEAD++LS+ FK  +  I   L    Q++L SAT P  V
Sbjct: 2   RILDLMNKRLVKPDTCGILVLDEADKLLSQDFKGMLDNIIAHLPPQRQILLYSATFPLSV 181

Query: 222 LEVTKKFMRDPIRILVKKEELTLEGIKQFYINVEREEWKLDTLCDLYETLTITQAVIFLN 281
            +  KK++++P  I +  EELTL+G+ Q+Y  V+ E+ K+  L  L+  L I Q++IF N
Sbjct: 182 EQFMKKYLKNPYEINLM-EELTLKGVTQYYAFVQ-EKQKVHCLNTLFSKLQINQSIIFCN 355

Query: 282 TRRKVDWLTEKMHARDFTVSALHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQ 341
           + ++V+ L +K+    ++   +H  M+Q+ R+ +  +FR G  R L+ +DL  RGID+Q 
Sbjct: 356 STQRVELLAKKITELGYSCYYIHAKMNQQHRNRVFHDFRQGLCRNLVCSDLFTRGIDIQA 535

Query: 342 VSLVINYDLPTNRENYIHXXXXXXXXXXXXVAINFVTEEDKRILRDIETFYNTTVEEMP 400
           V++VIN+D P + E Y+H            VAIN +T ED+  L  IE    T ++ +P
Sbjct: 536 VNVVINFDFPKHAETYLHRIGRSGRYGHLGVAINLITFEDRFSLHKIEQELGTEIKPIP 712
>02498
          Length = 1955

 Score =  124 bits (311), Expect = 8e-29,   Method: Compositional matrix adjust.
 Identities = 64/189 (33%), Positives = 107/189 (56%), Gaps = 7/189 (3%)
 Frame = +3

Query: 218 PTDVLEVTKKFMRDPIRILVKKEELTLEGIKQFYINVEREEWKLDTLCDLYETLTITQAV 277
           P+     +    +DP+ I +K+EE +L+ IKQ+YI+   +E K   LC++Y ++++ Q++
Sbjct: 693 PSGDAVCSAHHPQDPVIISLKREEESLDNIKQYYIDCNSQEEKYVALCNIYGSISVGQSM 872

Query: 278 IFLNTRRKVDWLTEKMHARDFTVSALHGDMDQKERDVIMREFRSGSSRVLITTDLLARGI 337
           IF + R    WL E+M A    V  L G++  ++R  I++ FR G  +VLITT++ ARGI
Sbjct: 873 IFCHKRSTAAWLAERMTADHHAVGLLTGELTIEQRAAIIKRFREGKEKVLITTNVSARGI 1052

Query: 338 DVQQVSLVINYDLPTNR------ENYIHXXXXXXXXXXXXVAINFV-TEEDKRILRDIET 390
           DV+ V++V+N+DLP  +      E Y+H            +AIN V       I+R IE 
Sbjct: 1053DVEMVTVVVNFDLPVTQDWRPDCETYLHRIGRTGRFGKNGIAINMVDNSRSMAIMRSIEK 1232

Query: 391 FYNTTVEEM 399
            +   +E++
Sbjct: 1233HFGRKIEKL 1259

 Score =  122 bits (307), Expect = 2e-28,   Method: Compositional matrix adjust.
 Identities = 84/217 (38%), Positives = 128/217 (58%), Gaps = 6/217 (2%)
 Frame = +1

Query: 19  DPDGVIESNWNEIVDNFDDMNLKESLLRGIYAYGFEKPSAIQQRA--IIPCIKGYDVIAQ 76
           DP+  + S     V +F+ +NLK  LL+G+Y  GF  PS IQ+ A  I+      ++IAQ
Sbjct: 106 DPNSPLYS-----VKSFEALNLKPQLLKGVYDMGFNAPSKIQETALPILLADPPVNMIAQ 270

Query: 77  AQSGTGKTATFAISILQQLEIEFKETQALVLAPTRELAQQIQKVILALGDYM-GATCHAC 135
           +QSGTGKTA F +++L +++I     Q L LAPT ELA QI +VI  +  +M G      
Sbjct: 271 SQSGTGKTAAFVLTMLSRVDISQTFPQCLCLAPTYELALQIGEVIEKMSKHMTGLEIRYA 450

Query: 136 IGGTNV-RNEMQKLQAEAPHIVVGTPGRVFDMLNR-RYLSPKWIKMFVLDEADEMLS-RG 192
           + G  V R E+   Q     IV+GTPG V D  +R + L  + +++FVLDEAD M+S +G
Sbjct: 451 VRGERVNRGEVLSEQ-----IVIGTPGTVMDWSHRFKALPLEKLRVFVLDEADVMISMQG 615

Query: 193 FKDQIYEIFQKLNTSIQVVLLSATMPTDVLEVTKKFM 229
            +DQ   I ++L++  Q++L SAT    V++  ++ +
Sbjct: 616 HQDQSTRIQKRLSSGCQMLLFSATYDQVVMQFAQRII 726
>09327
          Length = 1087

 Score =  119 bits (298), Expect = 2e-27,   Method: Compositional matrix adjust.
 Identities = 77/236 (32%), Positives = 126/236 (53%), Gaps = 4/236 (1%)
 Frame = +2

Query: 106 VLAPTRELAQQIQKVILALGDYMGATCHACIGGTNVRNEMQKLQAEAPHIVVGTPGRVFD 165
           +L PTRELAQQ+Q+V +  G           GG     ++++L   A  I + TPGR+ D
Sbjct: 20  LLVPTRELAQQVQEVAVEFGHSSRVRSVCVYGGAQRGPQLRELDRGA-EICIATPGRLID 196

Query: 166 MLNRRYLSPKWIKMFVLDEADEMLSRGFKDQIYEIFQKLNTSIQVVLLSATMPTDVLEVT 225
            L     + +     VLDEAD ML  GF+ QI +I +++    Q ++ SAT P +V ++ 
Sbjct: 197 FLESNRTNLRRCTYLVLDEADRMLDMGFEPQIRKIVEQIRPDRQTLMWSATWPKEVRKLA 376

Query: 226 KKFMRDPIRILVKKEELTLEG----IKQFYINVEREEWKLDTLCDLYETLTITQAVIFLN 281
           + F+ +  +I +   +LT       I    ++ E+EE KL  L +        + +IF+ 
Sbjct: 377 EDFIMEYTQINIGALQLTANHNILQIIDVCMDHEKEE-KLVKLLNEIMQEKENRTLIFVE 553

Query: 282 TRRKVDWLTEKMHARDFTVSALHGDMDQKERDVIMREFRSGSSRVLITTDLLARGI 337
           T+RK D +  +M    + V  +HGD  Q+ERD ++ +FR+G   VL+ TD+ +RG+
Sbjct: 554 TKRKCDDIHRRMKRDGWPVLCIHGDKSQQERDWVLNDFRNGRCPVLLATDVASRGL 721
>00739
          Length = 1313

 Score =  117 bits (292), Expect = 1e-26,   Method: Compositional matrix adjust.
 Identities = 71/256 (27%), Positives = 131/256 (51%), Gaps = 4/256 (1%)
 Frame = +3

Query: 150 AEAPHIVVGTPGRVFDMLNR-RYLSPKWIKMFVLDEADEMLSRGFKDQIYEIFQKLNTSI 208
           A  PHIV+ TPGR+ D ++     S K +K  V+DEAD +L   F  Q+  I  +L ++ 
Sbjct: 33  AVKPHIVISTPGRLADHIDSCDTFSLKRVKFLVMDEADRLLDDNFGAQLEPILTRLPSAR 212

Query: 209 QVVLLSATMPTDVLEVTKKFMRDPIRILVKKEELTLEGIKQFYINVE---REEWKLDTLC 265
           Q +L SAT+   V  +    +  P   + + E  T++ +++ Y+ V    ++ + +  L 
Sbjct: 213 QTLLFSATLSPTVNALRDSVLNKPFVWIQQSERATVDELQEDYVLVPASMKDAYMVHILD 392

Query: 266 DLYETLTITQAVIFLNTRRKVDWLTEKMHARDFTVSALHGDMDQKERDVIMREFRSGSSR 325
              +    +  +IF  T +    L   +    F+ + LH  + Q+ R   +  F+S  +R
Sbjct: 393 HWLKDHPRSSLIIFTXTCKYAQILGMMLEKLQFSCAVLHSMIPQRFRLSSLSRFKSNQTR 572

Query: 326 VLITTDLLARGIDVQQVSLVINYDLPTNRENYIHXXXXXXXXXXXXVAINFVTEEDKRIL 385
           +LI+TD+ +RG+D+  V L+IN+++P    +Y+H             +I+ VTE D +++
Sbjct: 573 ILISTDVASRGLDIPTVDLIINHNIPNRPRDYVHRVGRTARAGRCGQSISLVTEFDIKLI 752

Query: 386 RDIETFYNTTVEEMPM 401
           + IE+  N  + E P+
Sbjct: 753 KSIESHINCQMTEHPV 800
>02054
          Length = 1110

 Score = 81.3 bits (199), Expect(2) = 1e-26,   Method: Compositional matrix adjust.
 Identities = 46/172 (26%), Positives = 86/172 (50%)
 Frame = -3

Query: 229 MRDPIRILVKKEELTLEGIKQFYINVEREEWKLDTLCDLYETLTITQAVIFLNTRRKVDW 288
           +RDP+++ V  +  T++ ++Q Y+ +   ++K   L  +   L     ++F +T      
Sbjct: 769 LRDPVKVEVSNKYQTVDTLQQSYLFIP-AKYKDAYLVSILNELAGNSFMVFCSTCANTQR 593

Query: 289 LTEKMHARDFTVSALHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINY 348
           +   +    FT   LHG M Q +R   + +F+S    +LI TD+ +RG+D+  V +V+N 
Sbjct: 592 VALLLRNLGFTAIPLHGQMSQAKRLGSLNKFKSKDRSILIATDVASRGLDIPHVDVVLNL 413

Query: 349 DLPTNRENYIHXXXXXXXXXXXXVAINFVTEEDKRILRDIETFYNTTVEEMP 400
           D+PT+ ++Y+H             AI FV++ D  + + IE      + E P
Sbjct: 412 DIPTHSKDYMHRVGRTARAGRSGRAITFVSQYDVELYQRIEHLIGKKLSEYP 257

 Score = 56.6 bits (135), Expect(2) = 1e-26,   Method: Compositional matrix adjust.
 Identities = 29/84 (34%), Positives = 45/84 (53%), Gaps = 1/84 (1%)
 Frame = -2

Query: 150  AEAPHIVVGTPGRVFDML-NRRYLSPKWIKMFVLDEADEMLSRGFKDQIYEIFQKLNTSI 208
             + PHI++ TPGR+ D L N +  S + +K  V+DEAD +L   F+D++ +I + +    
Sbjct: 1010 GKKPHIIIATPGRLVDHLENTKGFSLRALKFLVMDEADRILDMNFQDEVDKILKVIPRER 831

Query: 209  QVVLLSATMPTDVLEVTKKFMRDP 232
               L SATM   V + T      P
Sbjct: 830  NTYLFSATMTNKVAKTTASITEGP 759
>01517
          Length = 2605

 Score =  116 bits (290), Expect = 2e-26,   Method: Compositional matrix adjust.
 Identities = 75/247 (30%), Positives = 126/247 (51%), Gaps = 11/247 (4%)
 Frame = +2

Query: 165 DMLNRRYLSPKWIKMFVLDEADEMLSRGFKDQIYEIFQK----LNTSIQVVLLSATMPTD 220
           DM+ R  +        VLDEAD ML  GF+ QI  I +K         Q ++ SAT P +
Sbjct: 5   DMMERGKIGMDHCNYLVLDEADRMLDMGFEPQIRRIVEKDTMPPTGQRQTLMFSATFPKE 184

Query: 221 VLEVTKKFMRDPIRILVKKEELTLEGIKQFYINVEREEWKLDTLCDLY-------ETLTI 273
           +  + + F+ + I + V +   T E I Q  + VE  E K   L DL        E+LT+
Sbjct: 185 IQLLARDFLDNYIFLAVGRVGSTSENITQKVVWVEEPE-KRSFLLDLLMASGTGPESLTL 361

Query: 274 TQAVIFLNTRRKVDWLTEKMHARDFTVSALHGDMDQKERDVIMREFRSGSSRVLITTDLL 333
               +F+ T++  D L + +   ++  +++HGD  Q+ER+  +R F++G   +L+ T + 
Sbjct: 362 ----VFVETKKGADSLEQFLMYENYPATSIHGDRSQREREDALRVFKNGDRPILVATAVA 529

Query: 334 ARGIDVQQVSLVINYDLPTNRENYIHXXXXXXXXXXXXVAINFVTEEDKRILRDIETFYN 393
           ARG+D+  V  VIN+DLP++ E Y+H            +A +F  ++++ I RD+     
Sbjct: 530 ARGLDIPNVRHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNDKNRNIARDMLDLLT 709

Query: 394 TTVEEMP 400
              +E+P
Sbjct: 710 EANQEVP 730
>04883
          Length = 1155

 Score =  101 bits (251), Expect = 6e-22,   Method: Compositional matrix adjust.
 Identities = 71/238 (29%), Positives = 117/238 (49%), Gaps = 5/238 (2%)
 Frame = +3

Query: 35  FDDMNLKESLLRGIYAYGFEKPSAIQQRAIIPCIKGYDVIAQAQSGTGKTATFA----IS 90
           F ++N  + ++  +    +  P+ IQ ++    + G D++  AQ+G+GKT  F     + 
Sbjct: 366 FTEVNFPDYVMNQVRRNSWTAPTPIQSQSWPVAMAGKDLVGIAQTGSGKTLAFMLPAIVH 545

Query: 91  ILQQLEIEFKETQ-ALVLAPTRELAQQIQKVILALGDYMGATCHACIGGTNVRNEMQKLQ 149
           I  Q  +E  +    L L PTRELAQQ+Q+V    G           GG     +++ L+
Sbjct: 546 INHQAYLERGDGPIVLALVPTRELAQQVQEVAQEFGHASRVRSVCVYGGAPRGPQLRDLE 725

Query: 150 AEAPHIVVGTPGRVFDMLNRRYLSPKWIKMFVLDEADEMLSRGFKDQIYEIFQKLNTSIQ 209
             A  I + TPGR+ D L     + +     VLDEAD ML  GF+ QI +I +++    Q
Sbjct: 726 RGA-EICIATPGRLIDFLESNRTNLRRCTYLVLDEADRMLDMGFEPQIRKIIEQIRPDRQ 902

Query: 210 VVLLSATMPTDVLEVTKKFMRDPIRILVKKEELTLEGIKQFYINVEREEWKLDTLCDL 267
            ++ SAT P +V ++ + F+ + +++ +   ELT        I+V  E  K D L  L
Sbjct: 903 TLMWSATWPKEVRKLAEDFIDEYVQVNIGALELTANHNILQIIDVCMEHEKEDKLVKL 1076
>00162
          Length = 2322

 Score =  101 bits (251), Expect = 7e-22,   Method: Compositional matrix adjust.
 Identities = 82/262 (31%), Positives = 127/262 (48%), Gaps = 5/262 (1%)
 Frame = +3

Query: 103 QALVLAPTRELAQQIQKVILALGDYMGATCHACIGGTNVRNEMQKLQAEAPHIVVGTPGR 162
           +AL++ PTRELA QI +V+  +  +   + +  IGG  +  E   +     +IV+ T GR
Sbjct: 141 EALIITPTRELAFQIYEVLNKIRTFHDFSANLVIGGKFMWRETHLMGKT--NIVICTVGR 314

Query: 163 VFDML-NRRYLSPKWIKMFVLDEADEMLSRGFKDQIYEIFQKLNTSIQVVLLSATMPTDV 221
           +   L + +      +K+ VLDEAD ++   F   +  I   L    Q +L SAT    V
Sbjct: 315 LLHHLESTQAFDVSELKVLVLDEADRIMDSKFAQDMDSIMSHLPPR-QTLLFSATQTMSV 491

Query: 222 LEVTKKFMRDPIRILVKK--EELTLEGIKQFYINVEREEWKLDTLCDLYETLTITQAVIF 279
             + +  ++DP  + V +  E +T  G++Q YI  E  E KL  L    +     + ++F
Sbjct: 492 KTLARLSLKDPSYVSVDRHAEYVTPTGLEQSYIVCELHE-KLSLLYSFLKNHPNNKIMVF 668

Query: 280 LNTRRKVDWLTE--KMHARDFTVSALHGDMDQKERDVIMREFRSGSSRVLITTDLLARGI 337
           L T ++  ++    K      +V  LHG + Q  R  I REF      +LITTDL  RG+
Sbjct: 669 LQTCKQARYVHTVIKRERPGMSVLVLHGGIPQLRRLDIYREFCRKQHVILITTDLACRGL 848

Query: 338 DVQQVSLVINYDLPTNRENYIH 359
           D   V+ VI  D P +   YIH
Sbjct: 849 DFPAVNWVIQLDCPVDVNTYIH 914
>31899
          Length = 453

 Score = 94.4 bits (233), Expect = 7e-20,   Method: Compositional matrix adjust.
 Identities = 54/117 (46%), Positives = 73/117 (62%), Gaps = 1/117 (0%)
 Frame = -1

Query: 29  NEIVDNFDDMNLKESLLRGIYAYGFEKPSAIQQRAIIPCIKGYDVIAQAQSGTGKTATFA 88
           +E VD F  + L + +L G+   GFE+PS IQ +AI     G D+I QA+SGTGKT  F+
Sbjct: 354 SESVD-FASLLLSKPVLNGLKNAGFERPSPIQLKAIPLGRCGLDLIVQAKSGTGKTCVFS 178

Query: 89  ISILQQLEIEFKETQALVLAPTRELAQQIQKVILALGDYM-GATCHACIGGTNVRNE 144
           +  L+ +E   + TQ LVLAPTRE+A QI +VI ++G  M G  CH  IGG  V  +
Sbjct: 177 VVALEGIETTARSTQVLVLAPTREIALQIWEVINSIGSAMSGLQCHTFIGGLPVHED 7
>11160
          Length = 646

 Score = 75.1 bits (183), Expect(2) = 1e-17,   Method: Compositional matrix adjust.
 Identities = 53/189 (28%), Positives = 93/189 (49%), Gaps = 15/189 (7%)
 Frame = -1

Query: 137 GGTNVRNEMQKLQAEAPHIVVGTPGRVFDMLNRR------YLSPKWIKMFVLDEADEMLS 190
           GG +  +++ K       I++ TPGR+ D+ +R+        S K +++ VLDEAD +L 
Sbjct: 646 GGVSCSHDISKFMKSGGSILIATPGRLDDLFSRKESGFNLAASVKALEVLVLDEADRLLD 467

Query: 191 RGFKDQIYEIFQKLNTSIQVVLLSATMPTDVLEVTKKFMRDPIRILVKKEELTLEG---- 246
            GF+  I  I   L    +  L SAT   +V  + +  +R+P+R+ VK+++L  E     
Sbjct: 466 MGFEASINTILGHLPKLRRTGLFSATQTDEVENLIRAGLRNPLRVTVKEKKLAGEADQRT 287

Query: 247 ---IKQFYINVEREEWKLDTLCDLYETLTITQAVIFLNTRRKVDWLTEKMHA--RDFTVS 301
              +  +Y+ VE EE K   L    +T    + ++F +T   VD+ +  +    +   V 
Sbjct: 286 PSTLSNYYMIVEAEE-KFSQLVKFLKTHHRDKLLLFFSTCACVDYFSMCLTQLLKHMQVL 110

Query: 302 ALHGDMDQK 310
           ++H  M QK
Sbjct: 109 SIHSKMKQK 83

 Score = 32.7 bits (73), Expect(2) = 1e-17,   Method: Compositional matrix adjust.
 Identities = 13/31 (41%), Positives = 22/31 (70%)
 Frame = -3

Query: 308 DQKERDVIMREFRSGSSRVLITTDLLARGID 338
           D+ E   +  +FRS +S +L+ TD++ARG+D
Sbjct: 95  DEAEEKPVFAKFRSITSGLLVCTDVMARGVD 3
>22006
          Length = 3414

 Score = 87.0 bits (214), Expect = 1e-17,   Method: Compositional matrix adjust.
 Identities = 47/135 (34%), Positives = 79/135 (58%), Gaps = 1/135 (0%)
 Frame = +2

Query: 56   PSAIQQRAIIPCIKGYDVIAQAQSGTGKTATFAISILQQLEIE-FKETQALVLAPTRELA 114
            P+ IQ++ I   ++G D++A A++G+GKTA F + +L++L++   K  +AL+L+PTRELA
Sbjct: 3005 PTPIQRKTIPVIMEGKDMVAMARTGSGKTAAFLVPMLERLKMHSSKGARALILSPTRELA 3184

Query: 115  QQIQKVILALGDYMGATCHACIGGTNVRNEMQKLQAEAPHIVVGTPGRVFDMLNRRYLSP 174
             Q  K    LG ++       +GG  + ++   L  + P I++ TPGR+  +L     S 
Sbjct: 3185 LQTLKFTKELGKFLDLRAAVILGGDRMEDQFSALH-QNPDIIIATPGRLLHVLVEMKKSL 3361

Query: 175  KWIKMFVLDEADEML 189
            K +   V DEAD + 
Sbjct: 3362 KEVIYVVFDEADRLF 3406
>14337
          Length = 693

 Score = 84.7 bits (208), Expect = 6e-17,   Method: Compositional matrix adjust.
 Identities = 48/144 (33%), Positives = 70/144 (48%)
 Frame = +2

Query: 257 EEWKLDTLCDLYETLTITQAVIFLNTRRKVDWLTEKMHARDFTVSALHGDMDQKERDVIM 316
           E  KL  + +L+        ++F+ ++++   L  +       V A+H D  Q ERD  +
Sbjct: 8   EAGKLMAMRNLFTEGITPPVLVFVQSKQRAKELYSEFMFDKHKVDAIHADKPQAERDATV 187

Query: 317 REFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHXXXXXXXXXXXXVAINF 376
           R F  G   VL+ T+L+ RGID + ++LVINYD PTN  +YIH             AI F
Sbjct: 188 RAFTEGRVWVLVCTELMGRGIDFKGINLVINYDFPTNAVSYIHRIGRTGRAGVPGRAITF 367

Query: 377 VTEEDKRILRDIETFYNTTVEEMP 400
            TE+D   LR I         E+P
Sbjct: 368 FTEQDVTHLRSIANIIKEAGCEVP 439
>19525
          Length = 585

 Score = 82.8 bits (203), Expect = 2e-16,   Method: Compositional matrix adjust.
 Identities = 57/189 (30%), Positives = 97/189 (51%), Gaps = 3/189 (1%)
 Frame = +2

Query: 98  EFKETQALVLAPTRELAQQIQKVILALGDYMGATCHACIGGTNVRNEMQKLQAEAPHIVV 157
           E   T+ LVL PTRELA Q+ +V   +  Y   +     GG +++ +   L+   P IVV
Sbjct: 2   ERATTRVLVLVPTRELAVQVYQVGQQISQYTKISICLAAGGLDIKGQEAALRL-CPDIVV 178

Query: 158 GTPGRVFDML-NRRYLSPKWIKMFVLDEADEMLSRGFKDQIYEIFQKLNTSIQVVLLSAT 216
            TPGR+ D L N    +   +++ VLDEAD ML   F  Q+ EI +  N   Q +L SAT
Sbjct: 179 ATPGRLIDHLHNAPNFTIAHVEILVLDEADRMLDEYFAAQMTEIIRMCNFQRQTMLFSAT 358

Query: 217 MPTDVLEVTKKFMRDPIRILVKKEELTLEGIKQFYINV-EREEWKLDTLCDLYETLTIT- 274
           M   V ++    +++ +++ V +      G++Q ++ + E +E   + +     + T   
Sbjct: 359 MSDAVQDLASVSLKEAVKVFVNQNTDIALGLQQEFVRIRENKEGDREAIVSSLVSRTFCD 538

Query: 275 QAVIFLNTR 283
           + ++FL T+
Sbjct: 539 KCMVFLQTK 565
>08036
          Length = 1226

 Score = 61.2 bits (147), Expect(2) = 1e-14,   Method: Compositional matrix adjust.
 Identities = 47/180 (26%), Positives = 93/180 (51%), Gaps = 4/180 (2%)
 Frame = +1

Query: 156 VVGTPGRVFDMLNRRYLSPKWIKMFVLDEADEMLSRGFKDQIYEIFQKLNTSIQVVLLSA 215
           VVGTP R+   L   +L    ++M V+DEAD + S G +  + ++ ++L    Q  L+SA
Sbjct: 1   VVGTPSRILAHLRAGHLELHTVQMLVVDEADLVFSFGHEADMKKLMEELPRIYQAFLMSA 180

Query: 216 TMPTDVLEVTKKFMRDPIRILVKKEELTLEG-IKQFYINVEREEWKLDTLCDLYETLTIT 274
           T+  DV  + K  + +P+ + +K+ +L     + Q+++  E ++     +  L   L   
Sbjct: 181 TLSEDVKALKKMVLHNPVILKLKESQLPESTQLTQYHVKCEVDDKFTLMVAVLKLGLVRG 360

Query: 275 QAVIFLNTRRKVDWLTE-KMHARDFTVSA--LHGDMDQKERDVIMREFRSGSSRVLITTD 331
           ++++F+N+   VD   + K+    F + A  L+ ++  K R  I+ +F  G   ++I +D
Sbjct: 361 KSILFVNS---VDSCYKLKLFLEPFGIPACVLNSELPVKSRCHIVSQFNEGLYDIIIASD 531

 Score = 36.6 bits (83), Expect(2) = 1e-14,   Method: Compositional matrix adjust.
 Identities = 15/27 (55%), Positives = 19/27 (70%)
 Frame = +3

Query: 333 LARGIDVQQVSLVINYDLPTNRENYIH 359
           +ARGID Q VS VIN++ P   + YIH
Sbjct: 609 VARGIDFQNVSNVINFEFPKTVDAYIH 689
>34295
          Length = 694

 Score = 72.8 bits (177), Expect = 3e-13,   Method: Compositional matrix adjust.
 Identities = 47/131 (35%), Positives = 65/131 (49%), Gaps = 1/131 (0%)
 Frame = -1

Query: 273 ITQAVIFLNTRRKVDWLTEKMHARDFTVSALHGDMDQKERDVIMREFRSGSSRVLITTDL 332
           I   +IF NT++    L+  +   +     LHG M QKER   +  F+S   R LI TD+
Sbjct: 544 IPNVMIFTNTKKYCQLLSMTLTNMEIENVCLHGFMRQKERVSALSRFKSNHIRTLIATDV 365

Query: 333 LARGIDVQQVSLVINYDLPTNRENYIHXXXXXXXXXXXXVAIN-FVTEEDKRILRDIETF 391
            ARG+D+  V LVIN+ LP   + YIH            VAI+ F    D  +L  IE  
Sbjct: 364 AARGLDIPSVQLVINHMLPRTPKEYIHRVGRTARAGRKGVAISIFRFPRDLELLGAIEEE 185

Query: 392 YNTTVEEMPMN 402
            NT + E P++
Sbjct: 184 INTKLTEHPID 152
>00617
          Length = 1505

 Score = 70.5 bits (171), Expect = 1e-12,   Method: Compositional matrix adjust.
 Identities = 32/110 (29%), Positives = 63/110 (57%)
 Frame = -3

Query: 298  FTVSALHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENY 357
            F+ + LH  + Q+ R   +  F+S  +R+LI+TD+ +RG+D+  V L+IN+++P    +Y
Sbjct: 1482 FSCAVLHSMIPQRFRLSSLSRFKSNQTRILISTDVASRGLDIPTVDLIINHNIPNRPRDY 1303

Query: 358  IHXXXXXXXXXXXXVAINFVTEEDKRILRDIETFYNTTVEEMPMNVADLI 407
            +H             +I+ VTE D ++++ IE+  N  + E P+   +++
Sbjct: 1302 VHRVGRTARAGRCGQSISLVTEFDIKLIKSIESHINCQMTEHPVKEKEVL 1153
>33025
          Length = 558

 Score = 62.0 bits (149), Expect = 4e-10,   Method: Compositional matrix adjust.
 Identities = 41/145 (28%), Positives = 73/145 (50%), Gaps = 4/145 (2%)
 Frame = +3

Query: 137 GGTNVRNEMQKLQAEAPHIVVGTPGRVFDMLNRRYLSPKWIKMFVLDEADEMLSRGFKDQ 196
           G T+ R +  ++   A ++VVGTPGR+ D +  + +S    +  +LDEAD ML  GF+ +
Sbjct: 63  GATDRRYQKSRIMKGA-NLVVGTPGRLLDFIGDQTISLGKCQYLILDEADRMLDMGFEPE 239

Query: 197 IYEIFQKLN----TSIQVVLLSATMPTDVLEVTKKFMRDPIRILVKKEELTLEGIKQFYI 252
           I ++         T  Q ++ SAT   D+  +   F+ D + I V         + Q ++
Sbjct: 240 IRKLVDTHGMPPKTQRQTLMFSATFKEDIQRLAGDFLNDYLFITVGIVGGACSDVTQTFL 419

Query: 253 NVEREEWKLDTLCDLYETLTITQAV 277
            V+R + K D LC++   +   ++V
Sbjct: 420 EVDRLQ-KRDHLCEILNEMGTAKSV 491
>19172
          Length = 484

 Score = 61.2 bits (147), Expect = 6e-10,   Method: Compositional matrix adjust.
 Identities = 24/64 (37%), Positives = 43/64 (67%)
 Frame = -1

Query: 274 TQAVIFLNTRRKVDWLTEKMHARDFTVSALHGDMDQKERDVIMREFRSGSSRVLITTDLL 333
           T+ +IF+ T+++VD +T  +  + +   A+HGD  Q+ERD ++  FR+G   +L+ TD+ 
Sbjct: 334 TKTIIFVETKKRVDEITRNISRQGWRACAIHGDKSQQERDFVLSSFRNGRHSILVATDVA 155

Query: 334 ARGI 337
           ARG+
Sbjct: 154 ARGL 143
>30136
          Length = 524

 Score = 58.5 bits (140), Expect = 4e-09,   Method: Compositional matrix adjust.
 Identities = 41/125 (32%), Positives = 66/125 (52%), Gaps = 7/125 (5%)
 Frame = +2

Query: 32  VDNFDDMNLKESLLRGIYAYGFEKPSAIQQRAIIPCIKGYDVIAQAQSGTGKTATFA--- 88
           + +F +  L + +++ I   G++ P+ IQ +     + G + +  A++G+GKT  +    
Sbjct: 128 IQDFAEAYLPDYVIKEIRRQGYKSPTPIQAQGWPIAMSGANFVGIAKTGSGKTLGYILPA 307

Query: 89  -ISILQQLEIEFKETQ-ALVLAPTRELAQQIQKVILALG--DYMGATCHACIGGTNVRNE 144
            + I  Q  ++  E   ALVLAPTRELAQQIQ+V    G   Y+  TC    GG     +
Sbjct: 308 IVHINNQQPLQRGEGPIALVLAPTRELAQQIQQVATEFGSSSYVRNTC--VFGGAPKGGQ 481

Query: 145 MQKLQ 149
           M+ LQ
Sbjct: 482 MRDLQ 496
>17708
          Length = 882

 Score = 58.5 bits (140), Expect = 5e-09,   Method: Compositional matrix adjust.
 Identities = 35/100 (35%), Positives = 60/100 (60%), Gaps = 4/100 (4%)
 Frame = +1

Query: 72  DVIAQAQSGTGKTATF---AISILQQLEIEFKE-TQALVLAPTRELAQQIQKVILALGDY 127
           D++  A++G+GKT  F   AI ++ +L+   +  T  ++++PTREL+ Q   V+  L  Y
Sbjct: 556 DLMGAAKTGSGKTLAFLIPAIELMYKLKFMPRNGTGCIIISPTRELSMQTFNVLTELLKY 735

Query: 128 MGATCHACIGGTNVRNEMQKLQAEAPHIVVGTPGRVFDML 167
              T    +GG N  +E++KL+ +  +I+V TPGR+ D L
Sbjct: 736 HHHTFGLIMGGVNRHDEVKKLK-KGVNIIVATPGRLLDHL 852
>12995
          Length = 1072

 Score = 57.8 bits (138), Expect = 9e-09,   Method: Compositional matrix adjust.
 Identities = 29/126 (23%), Positives = 59/126 (46%)
 Frame = +3

Query: 277 VIFLNTRRKVDWLTEKMHARDFTVSALHGDMDQKERDVIMREFRSGSSRVLITTDLLARG 336
           V+F+ T+  V++L   +       + ++  +DQ  R + + +F     +V++ TDL ARG
Sbjct: 141 VVFVATKHHVEYLNTLLTKCGIACTYIYSSLDQTARKIHVAKFTHKQVKVMLVTDLAARG 320

Query: 337 IDVQQVSLVINYDLPTNRENYIHXXXXXXXXXXXXVAINFVTEEDKRILRDIETFYNTTV 396
           ID+ Q+  V+N+  P   + ++H             A + V  ++   L D+  F    +
Sbjct: 321 IDIPQLDNVVNFHFPAKAKLFVHRVGRVARAGRSGTAYSLVAMDEVAHLVDLHVFLGRPL 500

Query: 397 EEMPMN 402
           +  P +
Sbjct: 501 KTAPQS 518
>17544
          Length = 1047

 Score = 53.5 bits (127), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 34/103 (33%), Positives = 55/103 (53%), Gaps = 17/103 (16%)
 Frame = +2

Query: 32  VDNFDDMNLKESLLRGIYAYGFEKPSAIQQRAIIPCIKGYDVIAQAQSGTGKTATFAISI 91
           +++F++  L E +   I    + KP+ +Q+ A+   +   D++A AQ+G+GKTA F + I
Sbjct: 629 INSFEECTLGEIIRNNIVLSKYNKPTPVQKFALPIVLGKRDLMACAQTGSGKTAAFLLPI 808

Query: 92  LQQL------EIEFKETQ-----------ALVLAPTRELAQQI 117
           L Q+          ++ Q           AL+LAPTRELA QI
Sbjct: 809 LNQVYENGPTPEALQQNQSRGYRRKMYPIALILAPTRELASQI 937
>10649
          Length = 472

 Score = 52.8 bits (125), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 28/70 (40%), Positives = 37/70 (52%)
 Frame = +1

Query: 290 TEKMHARDFTVSALHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYD 349
           +++  A   +V  LHG + Q  R  I REF      +LITTDL  RG+D   V+ VI  D
Sbjct: 43  SDQARAAGMSVLVLHGGIPQLRRLDIYREFCRKQHVILITTDLACRGLDFPAVNWVIQLD 222

Query: 350 LPTNRENYIH 359
            P +   YIH
Sbjct: 223 CPVDVNTYIH 252
>19151
          Length = 625

 Score = 51.6 bits (122), Expect = 6e-07,   Method: Compositional matrix adjust.
 Identities = 29/88 (32%), Positives = 49/88 (55%), Gaps = 7/88 (7%)
 Frame = -3

Query: 325 RVLITTDLLARGIDVQQVSLVINYDLP------TNRENYIHXXXXXXXXXXXXVAINFV- 377
           +VLITT++L+RGID++QV++V+N+DLP       + E Y+H            +AIN + 
Sbjct: 623 KVLITTNVLSRGIDIEQVTIVVNFDLPIDLRGNADCETYLHRIGRTGRFGKSGIAINLID 444

Query: 378 TEEDKRILRDIETFYNTTVEEMPMNVAD 405
            E+   + R IE  +   +  +  + AD
Sbjct: 443 GEKSMNVCRAIEKHFQKDIVYLNTDNAD 360
>11624
          Length = 2257

 Score = 48.9 bits (115), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 39/148 (26%), Positives = 65/148 (43%), Gaps = 9/148 (6%)
 Frame = -1

Query: 243 TLEGIKQFYINVEREEWKLDTLCDLYETLTITQAVIFLNTRRKVDWLTEKMHARDFTVSA 302
           T EG+ ++ +  +  E  L  L  L+  L     + F N+        E  H R   +  
Sbjct: 991 TPEGLTEYIVESDSSEKPLLVLHFLH-NLKFRSVLCFTNS-------VETTH-RLCLLVK 839

Query: 303 LHGDMDQKE---------RDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTN 353
           L+G +  KE         R  I+++F  G   +L+ +D +ARG+DV  V  VI+YD P  
Sbjct: 838 LYGGLSVKEFSSRLPGERRKKILKQFSKGKIDLLVCSDAMARGMDVDNVKYVISYDNPPY 659

Query: 354 RENYIHXXXXXXXXXXXXVAINFVTEED 381
            + YIH             AI+ + +++
Sbjct: 658 IKTYIHRVGRTARAGRAGTAISLLEKKE 575
>39583
          Length = 234

 Score = 46.2 bits (108), Expect = 2e-05,   Method: Composition-based stats.
 Identities = 17/44 (38%), Positives = 31/44 (70%)
 Frame = -3

Query: 316 MREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIH 359
           ++ F+ G   VL+ TDL +RG+D++ V  VIN+ +P+  ++Y+H
Sbjct: 160 LKRFKEGEIDVLLATDLASRGLDIEGVKTVINFTMPSTLKHYVH 29
>31781
          Length = 416

 Score = 42.7 bits (99), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 16/50 (32%), Positives = 33/50 (66%)
 Frame = -2

Query: 231 DPIRILVKKEELTLEGIKQFYINVEREEWKLDTLCDLYETLTITQAVIFL 280
           +P+ I +++EE +L+ I+Q+YI       K   LC++Y ++++ Q++IF 
Sbjct: 277 NPVTIRLRREEESLDNIQQYYIRCRTLSDKYRALCNIYGSISVGQSMIFC 128
>12121
          Length = 465

 Score = 36.6 bits (83), Expect = 0.021,   Method: Compositional matrix adjust.
 Identities = 17/39 (43%), Positives = 21/39 (53%)
 Frame = -3

Query: 155 IVVGTPGRVFDMLNRRYLSPKWIKMFVLDEADEMLSRGF 193
           I + TPGR+ D L     + +     VLDEAD ML  GF
Sbjct: 463 ICIATPGRLIDFLESNRTNLRRCTYLVLDEADRMLDMGF 347
>31220
          Length = 818

 Score = 34.3 bits (77), Expect = 0.082,   Method: Compositional matrix adjust.
 Identities = 21/71 (29%), Positives = 32/71 (45%)
 Frame = +2

Query: 334 ARGIDVQQVSLVINYDLPTNRENYIHXXXXXXXXXXXXVAINFVTEEDKRILRDIETFYN 393
           +RGID Q V+ VIN+D P +  +YIH              ++FV                
Sbjct: 164 SRGIDFQGVNNVINFDFPLDVTSYIHRAGRTARGNNTGSVLSFV---------------- 295

Query: 394 TTVEEMPMNVA 404
            +V+E+P+N A
Sbjct: 296 -SVKELPINQA 325
>14329
          Length = 819

 Score = 33.9 bits (76), Expect = 0.11,   Method: Compositional matrix adjust.
 Identities = 30/88 (34%), Positives = 39/88 (44%), Gaps = 4/88 (4%)
 Frame = -3

Query: 65  IPCIKGYDVIAQAQS--GTGKTATFAISILQQLEIEFKETQALVLAPTRELAQQIQKVIL 122
           IP   G+ V     S  G G+T    +  +Q  +    ET  L L       Q+ Q V L
Sbjct: 274 IPAAAGFGVFVTFMSRLGRGRTWPLYLFFVQGYDGRGXET-CLHLCHLYLWTQESQNVCL 98

Query: 123 AL--GDYMGATCHACIGGTNVRNEMQKL 148
            L  GD++  TCH+  GG  V  EM KL
Sbjct: 97  LLS*GDWLTTTCHSDCGGGTVW-EMLKL 17
>33083
          Length = 1931

 Score = 32.0 bits (71), Expect = 0.49,   Method: Compositional matrix adjust.
 Identities = 11/25 (44%), Positives = 16/25 (64%)
 Frame = +1

Query: 335 RGIDVQQVSLVINYDLPTNRENYIH 359
           RG+D+ QV  ++ YD P   + YIH
Sbjct: 1   RGLDIPQVDWIVQYDPPDESKEYIH 75
>10351
          Length = 575

 Score = 30.8 bits (68), Expect = 0.94,   Method: Compositional matrix adjust.
 Identities = 16/38 (42%), Positives = 21/38 (55%)
 Frame = +2

Query: 23  VIESNWNEIVDNFDDMNLKESLLRGIYAYGFEKPSAIQ 60
           V + +W+   D FDD NL    LRG+Y YG     AI+
Sbjct: 74  VKKVHWDCAWDTFDDSNL----LRGVYEYGMGSWEAIR 175
>06438
          Length = 989

 Score = 30.8 bits (68), Expect = 1.0,   Method: Compositional matrix adjust.
 Identities = 13/32 (40%), Positives = 17/32 (53%)
 Frame = +1

Query: 328 ITTDLLARGIDVQQVSLVINYDLPTNRENYIH 359
           +T  L  RG+D   V+ VI  D P +   YIH
Sbjct: 25  LTVTLACRGLDFPAVNWVIQLDCPVDVNTYIH 120
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|21450625|ref|NP_659207.1| eukaryotic translation
initiation factor 4A1 [Mus musculus]
         (406 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

01062                                                                 538   e-153
09316                                                                 224   6e-59
19640                                                                 146   4e-46
00621                                                                 177   9e-45
07310                                                                 172   2e-43
02498                                                                 125   4e-29
09327                                                                 122   3e-28
00739                                                                 115   2e-26
01517                                                                 114   8e-26
02054                                                                  77   1e-25
04883                                                                 104   7e-23
00162                                                                 101   5e-22
31899                                                                  98   7e-21
11160                                                                  75   9e-18
22006                                                                  87   2e-17
19525                                                                  86   3e-17
14337                                                                  84   1e-16
08036                                                                  60   7e-15
34295                                                                  70   1e-12
00617                                                                  69   3e-12
33025                                                                  63   2e-10
19172                                                                  62   4e-10
12995                                                                  60   1e-09
17708                                                                  58   7e-09
17544                                                                  57   1e-08
30136                                                                  56   2e-08
10649                                                                  52   4e-07
19151                                                                  52   4e-07
11624                                                                  49   3e-06
39583                                                                  46   2e-05
31781                                                                  42   4e-04
12121                                                                  36   0.028
31220                                                                  34   0.11 
33083                                                                  32   0.44 
10351                                                                  32   0.45 
06438                                                                  31   0.84 
>01062
          Length = 2138

 Score =  538 bits (1387), Expect = e-153,   Method: Compositional matrix adjust.
 Identities = 255/378 (67%), Positives = 310/378 (82%)
 Frame = -3

Query: 29   EIVDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAI 88
            E+  +FD+M + E LLRGIYAYGFEKPSAIQQRA+ P +KG DVIAQAQSGTGKTATF+I
Sbjct: 2088 EVTPTFDNMGIREELLRGIYAYGFEKPSAIQQRAVKPIVKGRDVIAQAQSGTGKTATFSI 1909

Query: 89   SILQQIELDLKATQALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTNVRAEVQKLQ 148
            S+LQ +++ L+ TQAL+L+PTRELA QIQKV++ALGDYM   CH+CIGGTN+  +++KL 
Sbjct: 1908 SVLQCLDIQLRETQALILSPTRELATQIQKVMLALGDYMNVQCHSCIGGTNIGEDIRKLD 1729

Query: 149  MEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRGFKDQIYDIFQKLNSNTQ 208
                HI+ GTPGRVFDM+ RR L  + IKM +LDEADEML++GFK+QIYD+++ L   TQ
Sbjct: 1728 Y-GQHIVSGTPGRVFDMIKRRNLRTRSIKMMILDEADEMLNKGFKEQIYDVYRYLPPATQ 1552

Query: 209  VVLLSATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQFYINVEREEWKLDTLCDLYE 268
            V+L+SAT+P ++LE+T KFM DPIRILVK++ELTLEGI+QF++ VEREEWK DTLCDLY+
Sbjct: 1551 VILISATLPHEILEMTNKFMTDPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYD 1372

Query: 269  TLTITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREFRSGSSRVLIT 328
            TLTITQAVIF NT+RKVDWLTEKM   +FTVS+MHGDM QKER+ IM+ FR+G SRVLIT
Sbjct: 1371 TLTITQAVIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKEREAIMKVFRAGDSRVLIT 1192

Query: 329  TDLLARGIDVQQVSLVINYDLPTNRENYIHXXXXXXXXXXXXVAINMVTEEDKRTLRDIE 388
            TD+ ARGIDVQQVSLVINYDLP NRE YIH            VAIN V  +D R LRDIE
Sbjct: 1191 TDVWARGIDVQQVSLVINYDLPNNRELYIHRIGRSGRFGRKGVAINFVKNDDIRILRDIE 1012

Query: 389  TFYNTSIEEMPLNVADLI 406
             +Y+T I+EMP+NVADLI
Sbjct: 1011 QYYSTQIDEMPMNVADLI 958
>09316
          Length = 2312

 Score =  224 bits (571), Expect = 6e-59,   Method: Compositional matrix adjust.
 Identities = 136/401 (33%), Positives = 215/401 (53%), Gaps = 9/401 (2%)
 Frame = +2

Query: 8    RSRDNGPDGMEPEGV----IESNWNEIVDS-FDDMNLSESLLRGIYAYGFEKPSAIQQRA 62
            R  +   DG   EG     ++  +  I  S F D  L   LLR I   GFE PS +Q   
Sbjct: 758  RRNETAVDGAGGEGQAKKDVKGTYVSIHSSGFRDFLLKPELLRAIIDCGFEHPSEVQHEC 937

Query: 63   ILPCIKGYDVIAQAQSGTGKTATFAISILQQIELDLKATQALVLAPTRELAQQIQKVVMA 122
            I   I   DV+ QA+SG GKTA F ++ LQQ+E        LV+A TRELA QI K    
Sbjct: 938  IPQAILSMDVLCQAKSGMGKTAVFVLATLQQLEPVDGQVSVLVMAHTRELAFQISKEYER 1117

Query: 123  LGDYMG-ASCHACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVL 181
               YM         GG +V+ + + L    PHI+VGTPGR+  +     L+ K IK F+L
Sbjct: 1118 FSKYMNNVKIAVFFGGMSVKKDEEVLSKNCPHIVVGTPGRLHALAKANNLNLKKIKHFIL 1297

Query: 182  DEADEMLSR-GFKDQIYDIFQKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKE- 239
            DE D+ML+    +  + +IF+      QV++ SAT+  ++  + KKFM+DP+ + V  + 
Sbjct: 1298 DECDKMLADLDMRRDVQEIFRLTPHEKQVMMFSATLSKEIRPICKKFMQDPMEVYVDDDS 1477

Query: 240  ELTLEGIRQFYINVEREEWKLDTLCDLYETLTITQAVIFINTRRKVDWLTEKMHARDFTV 299
            +LTL G++Q Y  ++  E K   L +L + L   Q +IF+ +  +   L++ +  ++F  
Sbjct: 1478 KLTLHGLQQHYCKLKDNE-KNRKLFELLDVLEFNQVIIFVKSVPRCMALSQLLLEQNFPA 1654

Query: 300  SAMHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHX 359
             A+H  M Q+ER    ++F+    R+L+ T+L  RG+D+++V++V NYD+P + + Y+H 
Sbjct: 1655 IAIHRQMTQEERLSRYQQFKDFQKRILVATNLFGRGMDIERVNIVFNYDMPEDSDTYLHR 1834

Query: 360  XXXXXXXXXXXVAINMVTEE-DKRTLRDIETFYNTSIEEMP 399
                       +AI  V++E D + L D++  +  +I E+P
Sbjct: 1835 VARAGRFGTKGLAITFVSDENDAKILNDVQERFEVNITELP 1957
>19640
          Length = 456

 Score =  146 bits (369), Expect(2) = 4e-46,   Method: Compositional matrix adjust.
 Identities = 67/82 (81%), Positives = 78/82 (95%)
 Frame = -1

Query: 277 IFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREFRSGSSRVLITTDLLARGI 336
           IF NTRRKVD LT++M + +FTVSAMHGDM+Q++R+VIM++FRSGSSRVLITTDLLARGI
Sbjct: 456 IFCNTRRKVDQLTQEMSSHNFTVSAMHGDMEQRDREVIMKQFRSGSSRVLITTDLLARGI 277

Query: 337 DVQQVSLVINYDLPTNRENYIH 358
           DVQQVSLVINYDLP+NRENYIH
Sbjct: 276 DVQQVSLVINYDLPSNRENYIH 211

 Score = 56.6 bits (135), Expect(2) = 4e-46,   Method: Compositional matrix adjust.
 Identities = 24/36 (66%), Positives = 32/36 (88%)
 Frame = -3

Query: 371 VAINMVTEEDKRTLRDIETFYNTSIEEMPLNVADLI 406
           VAIN +T++D+R L+DIE FY+T+IEEMP N+ADLI
Sbjct: 175 VAINFITDDDRRILKDIEQFYHTTIEEMPANIADLI 68
>00621
          Length = 2263

 Score =  177 bits (448), Expect = 9e-45,   Method: Compositional matrix adjust.
 Identities = 109/396 (27%), Positives = 195/396 (49%), Gaps = 35/396 (8%)
 Frame = +1

Query: 34  FDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISIL-- 91
           + + +L   ++  I   G+++P+ IQ +AI   ++  D+I  A++G+GKTA F I +L  
Sbjct: 259 WKESDLGADIMEVIDRVGYKEPTPIQMQAIPIGLQNRDIIGVAETGSGKTAAFLIPLLVW 438

Query: 92  -------QQIELDLKATQALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTNVRAEV 144
                  +++E   +   A++LAPTRELAQQI++     G+ +G    + IGG +   + 
Sbjct: 439 IQSLPKIERLEDADQGPYAVILAPTRELAQQIEEETRKFGEGLGIRVVSVIGGISREEQG 618

Query: 145 QKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRGFKDQIYDI----- 199
            KLQ +   +++ TPGR+ D+L  RYL        V+DEAD M++ GF+ ++  I     
Sbjct: 619 FKLQ-QGCEVVIATPGRMIDVLENRYLVLNQCTYVVMDEADRMINMGFEPEVRKILDYLP 795

Query: 200 --------------------FQKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKE 239
                               F+  +   Q V+ +ATMP  V  + + F+R P  + +   
Sbjct: 796 VSNQKPDNDDAEDDLKMLQNFKSKHKYRQTVMFTATMPPQVERLARTFLRRPTVVYIGNV 975

Query: 240 ELTLEGIRQF-YINVEREEWKLDTLCDLYETLTITQAVIFINTRRKVDWLTEKMHARDFT 298
              +E + Q  Y+  E E+ K   L ++         +IF+N ++  D L + +    F 
Sbjct: 976 GKPVERVEQIVYMLTESEKRK--KLIEVLNAGVDPPIIIFVNQKKGADVLAKSLEKMGFN 1149

Query: 299 VSAMHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIH 358
            + +HG   Q++R+  +   + G+  +++ TD+  RGID++ VSLV+NYD+    E+Y H
Sbjct: 1150ATTLHGGKGQEQREYALASLKGGAKDIMVATDVAGRGIDIKDVSLVLNYDMARTIEDYTH 1329

Query: 359 XXXXXXXXXXXXVAINMVTEEDKRTLRDIETFYNTS 394
                        +I  +T+ED     D++    +S
Sbjct: 1330RIGRTGRAGKEGTSITFLTKEDSMVFYDLKQLMLSS 1437
>07310
          Length = 712

 Score =  172 bits (436), Expect = 2e-43,   Method: Compositional matrix adjust.
 Identities = 88/239 (36%), Positives = 144/239 (60%)
 Frame = +2

Query: 161 RVFDMLNRRYLSPKYIKMFVLDEADEMLSRGFKDQIYDIFQKLNSNTQVVLLSATMPSDV 220
           R+ D++N+R + P    + VLDEAD++LS+ FK  + +I   L    Q++L SAT P  V
Sbjct: 2   RILDLMNKRLVKPDTCGILVLDEADKLLSQDFKGMLDNIIAHLPPQRQILLYSATFPLSV 181

Query: 221 LEVTKKFMRDPIRILVKKEELTLEGIRQFYINVEREEWKLDTLCDLYETLTITQAVIFIN 280
            +  KK++++P  I +  EELTL+G+ Q+Y  V+ E+ K+  L  L+  L I Q++IF N
Sbjct: 182 EQFMKKYLKNPYEINLM-EELTLKGVTQYYAFVQ-EKQKVHCLNTLFSKLQINQSIIFCN 355

Query: 281 TRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQ 340
           + ++V+ L +K+    ++   +H  M+Q+ R+ +  +FR G  R L+ +DL  RGID+Q 
Sbjct: 356 STQRVELLAKKITELGYSCYYIHAKMNQQHRNRVFHDFRQGLCRNLVCSDLFTRGIDIQA 535

Query: 341 VSLVINYDLPTNRENYIHXXXXXXXXXXXXVAINMVTEEDKRTLRDIETFYNTSIEEMP 399
           V++VIN+D P + E Y+H            VAIN++T ED+ +L  IE    T I+ +P
Sbjct: 536 VNVVINFDFPKHAETYLHRIGRSGRYGHLGVAINLITFEDRFSLHKIEQELGTEIKPIP 712
>02498
          Length = 1955

 Score =  125 bits (313), Expect = 4e-29,   Method: Compositional matrix adjust.
 Identities = 81/204 (39%), Positives = 122/204 (59%), Gaps = 6/204 (2%)
 Frame = +1

Query: 31  VDSFDDMNLSESLLRGIYAYGFEKPSAIQQRA--ILPCIKGYDVIAQAQSGTGKTATFAI 88
           V SF+ +NL   LL+G+Y  GF  PS IQ+ A  IL      ++IAQ+QSGTGKTA F +
Sbjct: 130 VKSFEALNLKPQLLKGVYDMGFNAPSKIQETALPILLADPPVNMIAQSQSGTGKTAAFVL 309

Query: 89  SILQQIELDLKATQALVLAPTRELAQQIQKVVMALGDYM-GASCHACIGGTNV-RAEVQK 146
           ++L ++++     Q L LAPT ELA QI +V+  +  +M G      + G  V R EV  
Sbjct: 310 TMLSRVDISQTFPQCLCLAPTYELALQIGEVIEKMSKHMTGLEIRYAVRGERVNRGEVLS 489

Query: 147 LQMEAPHIIVGTPGRVFDMLNR-RYLSPKYIKMFVLDEADEMLS-RGFKDQIYDIFQKLN 204
            Q     I++GTPG V D  +R + L  + +++FVLDEAD M+S +G +DQ   I ++L+
Sbjct: 490 EQ-----IVIGTPGTVMDWSHRFKALPLEKLRVFVLDEADVMISMQGHQDQSTRIQKRLS 654

Query: 205 SNTQVVLLSATMPSDVLEVTKKFM 228
           S  Q++L SAT    V++  ++ +
Sbjct: 655 SGCQMLLFSATYDQVVMQFAQRII 726

 Score =  124 bits (311), Expect = 7e-29,   Method: Compositional matrix adjust.
 Identities = 65/191 (34%), Positives = 111/191 (58%), Gaps = 9/191 (4%)
 Frame = +3

Query: 217 PSDVLEVTKKFMRDPIRILVKKEELTLEGIRQFYINVEREEWKLDTLCDLYETLTITQAV 276
           PS     +    +DP+ I +K+EE +L+ I+Q+YI+   +E K   LC++Y ++++ Q++
Sbjct: 693 PSGDAVCSAHHPQDPVIISLKREEESLDNIKQYYIDCNSQEEKYVALCNIYGSISVGQSM 872

Query: 277 IFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREFRSGSSRVLITTDLLARGI 336
           IF + R    WL E+M A    V  + G++  ++R  I++ FR G  +VLITT++ ARGI
Sbjct: 873 IFCHKRSTAAWLAERMTADHHAVGLLTGELTIEQRAAIIKRFREGKEKVLITTNVSARGI 1052

Query: 337 DVQQVSLVINYDLPTNR------ENYIHXXXXXXXXXXXXVAINMVTEEDKRT---LRDI 387
           DV+ V++V+N+DLP  +      E Y+H            +AINMV  ++ R+   +R I
Sbjct: 1053DVEMVTVVVNFDLPVTQDWRPDCETYLHRIGRTGRFGKNGIAINMV--DNSRSMAIMRSI 1226

Query: 388 ETFYNTSIEEM 398
           E  +   IE++
Sbjct: 1227EKHFGRKIEKL 1259
>09327
          Length = 1087

 Score =  122 bits (306), Expect = 3e-28,   Method: Compositional matrix adjust.
 Identities = 77/236 (32%), Positives = 126/236 (53%), Gaps = 4/236 (1%)
 Frame = +2

Query: 105 VLAPTRELAQQIQKVVMALGDYMGASCHACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFD 164
           +L PTRELAQQ+Q+V +  G           GG     ++++L   A  I + TPGR+ D
Sbjct: 20  LLVPTRELAQQVQEVAVEFGHSSRVRSVCVYGGAQRGPQLRELDRGA-EICIATPGRLID 196

Query: 165 MLNRRYLSPKYIKMFVLDEADEMLSRGFKDQIYDIFQKLNSNTQVVLLSATMPSDVLEVT 224
            L     + +     VLDEAD ML  GF+ QI  I +++  + Q ++ SAT P +V ++ 
Sbjct: 197 FLESNRTNLRRCTYLVLDEADRMLDMGFEPQIRKIVEQIRPDRQTLMWSATWPKEVRKLA 376

Query: 225 KKFMRDPIRILVKKEELTLEG----IRQFYINVEREEWKLDTLCDLYETLTITQAVIFIN 280
           + F+ +  +I +   +LT       I    ++ E+EE KL  L +        + +IF+ 
Sbjct: 377 EDFIMEYTQINIGALQLTANHNILQIIDVCMDHEKEE-KLVKLLNEIMQEKENRTLIFVE 553

Query: 281 TRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREFRSGSSRVLITTDLLARGI 336
           T+RK D +  +M    + V  +HGD  Q+ERD ++ +FR+G   VL+ TD+ +RG+
Sbjct: 554 TKRKCDDIHRRMKRDGWPVLCIHGDKSQQERDWVLNDFRNGRCPVLLATDVASRGL 721
>00739
          Length = 1313

 Score =  115 bits (289), Expect = 2e-26,   Method: Compositional matrix adjust.
 Identities = 69/254 (27%), Positives = 129/254 (50%), Gaps = 4/254 (1%)
 Frame = +3

Query: 152 PHIIVGTPGRVFDMLNR-RYLSPKYIKMFVLDEADEMLSRGFKDQIYDIFQKLNSNTQVV 210
           PHI++ TPGR+ D ++     S K +K  V+DEAD +L   F  Q+  I  +L S  Q +
Sbjct: 42  PHIVISTPGRLADHIDSCDTFSLKRVKFLVMDEADRLLDDNFGAQLEPILTRLPSARQTL 221

Query: 211 LLSATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQFYINVE---REEWKLDTLCDLY 267
           L SAT+   V  +    +  P   + + E  T++ +++ Y+ V    ++ + +  L    
Sbjct: 222 LFSATLSPTVNALRDSVLNKPFVWIQQSERATVDELQEDYVLVPASMKDAYMVHILDHWL 401

Query: 268 ETLTITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREFRSGSSRVLI 327
           +    +  +IF  T +    L   +    F+ + +H  + Q+ R   +  F+S  +R+LI
Sbjct: 402 KDHPRSSLIIFTXTCKYAQILGMMLEKLQFSCAVLHSMIPQRFRLSSLSRFKSNQTRILI 581

Query: 328 TTDLLARGIDVQQVSLVINYDLPTNRENYIHXXXXXXXXXXXXVAINMVTEEDKRTLRDI 387
           +TD+ +RG+D+  V L+IN+++P    +Y+H             +I++VTE D + ++ I
Sbjct: 582 STDVASRGLDIPTVDLIINHNIPNRPRDYVHRVGRTARAGRCGQSISLVTEFDIKLIKSI 761

Query: 388 ETFYNTSIEEMPLN 401
           E+  N  + E P+ 
Sbjct: 762 ESHINCQMTEHPVK 803
>01517
          Length = 2605

 Score =  114 bits (285), Expect = 8e-26,   Method: Compositional matrix adjust.
 Identities = 73/247 (29%), Positives = 126/247 (51%), Gaps = 11/247 (4%)
 Frame = +2

Query: 164 DMLNRRYLSPKYIKMFVLDEADEMLSRGFKDQIYDIFQK----LNSNTQVVLLSATMPSD 219
           DM+ R  +   +    VLDEAD ML  GF+ QI  I +K         Q ++ SAT P +
Sbjct: 5   DMMERGKIGMDHCNYLVLDEADRMLDMGFEPQIRRIVEKDTMPPTGQRQTLMFSATFPKE 184

Query: 220 VLEVTKKFMRDPIRILVKKEELTLEGIRQFYINVEREEWKLDTLCDLY-------ETLTI 272
           +  + + F+ + I + V +   T E I Q  + VE  E K   L DL        E+LT+
Sbjct: 185 IQLLARDFLDNYIFLAVGRVGSTSENITQKVVWVEEPE-KRSFLLDLLMASGTGPESLTL 361

Query: 273 TQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREFRSGSSRVLITTDLL 332
               +F+ T++  D L + +   ++  +++HGD  Q+ER+  +R F++G   +L+ T + 
Sbjct: 362 ----VFVETKKGADSLEQFLMYENYPATSIHGDRSQREREDALRVFKNGDRPILVATAVA 529

Query: 333 ARGIDVQQVSLVINYDLPTNRENYIHXXXXXXXXXXXXVAINMVTEEDKRTLRDIETFYN 392
           ARG+D+  V  VIN+DLP++ E Y+H            +A +   ++++   RD+     
Sbjct: 530 ARGLDIPNVRHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNDKNRNIARDMLDLLT 709

Query: 393 TSIEEMP 399
            + +E+P
Sbjct: 710 EANQEVP 730
>02054
          Length = 1110

 Score = 77.0 bits (188), Expect(2) = 1e-25,   Method: Compositional matrix adjust.
 Identities = 44/172 (25%), Positives = 84/172 (48%)
 Frame = -3

Query: 228 MRDPIRILVKKEELTLEGIRQFYINVEREEWKLDTLCDLYETLTITQAVIFINTRRKVDW 287
           +RDP+++ V  +  T++ ++Q Y+ +   ++K   L  +   L     ++F +T      
Sbjct: 769 LRDPVKVEVSNKYQTVDTLQQSYLFIP-AKYKDAYLVSILNELAGNSFMVFCSTCANTQR 593

Query: 288 LTEKMHARDFTVSAMHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINY 347
           +   +    FT   +HG M Q +R   + +F+S    +LI TD+ +RG+D+  V +V+N 
Sbjct: 592 VALLLRNLGFTAIPLHGQMSQAKRLGSLNKFKSKDRSILIATDVASRGLDIPHVDVVLNL 413

Query: 348 DLPTNRENYIHXXXXXXXXXXXXVAINMVTEEDKRTLRDIETFYNTSIEEMP 399
           D+PT+ ++Y+H             AI  V++ D    + IE      + E P
Sbjct: 412 DIPTHSKDYMHRVGRTARAGRSGRAITFVSQYDVELYQRIEHLIGKKLSEYP 257

 Score = 57.4 bits (137), Expect(2) = 1e-25,   Method: Compositional matrix adjust.
 Identities = 30/83 (36%), Positives = 45/83 (54%), Gaps = 1/83 (1%)
 Frame = -2

Query: 150  EAPHIIVGTPGRVFDML-NRRYLSPKYIKMFVLDEADEMLSRGFKDQIYDIFQKLNSNTQ 208
            + PHII+ TPGR+ D L N +  S + +K  V+DEAD +L   F+D++  I + +     
Sbjct: 1007 KKPHIIIATPGRLVDHLENTKGFSLRALKFLVMDEADRILDMNFQDEVDKILKVIPRERN 828

Query: 209  VVLLSATMPSDVLEVTKKFMRDP 231
              L SATM + V + T      P
Sbjct: 827  TYLFSATMTNKVAKTTASITEGP 759
>04883
          Length = 1155

 Score =  104 bits (259), Expect = 7e-23,   Method: Compositional matrix adjust.
 Identities = 69/239 (28%), Positives = 116/239 (48%), Gaps = 5/239 (2%)
 Frame = +3

Query: 33  SFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISILQ 92
           +F ++N  + ++  +    +  P+ IQ ++    + G D++  AQ+G+GKT  F +  + 
Sbjct: 363 TFTEVNFPDYVMNQVRRNSWTAPTPIQSQSWPVAMAGKDLVGIAQTGSGKTLAFMLPAIV 542

Query: 93  QIELDLKATQA-----LVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTNVRAEVQKL 147
            I       +      L L PTRELAQQ+Q+V    G           GG     +++ L
Sbjct: 543 HINHQAYLERGDGPIVLALVPTRELAQQVQEVAQEFGHASRVRSVCVYGGAPRGPQLRDL 722

Query: 148 QMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRGFKDQIYDIFQKLNSNT 207
           +  A  I + TPGR+ D L     + +     VLDEAD ML  GF+ QI  I +++  + 
Sbjct: 723 ERGA-EICIATPGRLIDFLESNRTNLRRCTYLVLDEADRMLDMGFEPQIRKIIEQIRPDR 899

Query: 208 QVVLLSATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQFYINVEREEWKLDTLCDL 266
           Q ++ SAT P +V ++ + F+ + +++ +   ELT        I+V  E  K D L  L
Sbjct: 900 QTLMWSATWPKEVRKLAEDFIDEYVQVNIGALELTANHNILQIIDVCMEHEKEDKLVKL 1076
>00162
          Length = 2322

 Score =  101 bits (252), Expect = 5e-22,   Method: Compositional matrix adjust.
 Identities = 81/262 (30%), Positives = 126/262 (48%), Gaps = 5/262 (1%)
 Frame = +3

Query: 102 QALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTNVRAEVQKLQMEAPHIIVGTPGR 161
           +AL++ PTRELA QI +V+  +  +   S +  IGG  +  E     M   +I++ T GR
Sbjct: 141 EALIITPTRELAFQIYEVLNKIRTFHDFSANLVIGGKFMWRETH--LMGKTNIVICTVGR 314

Query: 162 VFDML-NRRYLSPKYIKMFVLDEADEMLSRGFKDQIYDIFQKLNSNTQVVLLSATMPSDV 220
           +   L + +      +K+ VLDEAD ++   F   +  I   L    Q +L SAT    V
Sbjct: 315 LLHHLESTQAFDVSELKVLVLDEADRIMDSKFAQDMDSIMSHLPPR-QTLLFSATQTMSV 491

Query: 221 LEVTKKFMRDPIRILVKK--EELTLEGIRQFYINVEREEWKLDTLCDLYETLTITQAVIF 278
             + +  ++DP  + V +  E +T  G+ Q YI  E  E KL  L    +     + ++F
Sbjct: 492 KTLARLSLKDPSYVSVDRHAEYVTPTGLEQSYIVCELHE-KLSLLYSFLKNHPNNKIMVF 668

Query: 279 INTRRKVDWLTE--KMHARDFTVSAMHGDMDQKERDVIMREFRSGSSRVLITTDLLARGI 336
           + T ++  ++    K      +V  +HG + Q  R  I REF      +LITTDL  RG+
Sbjct: 669 LQTCKQARYVHTVIKRERPGMSVLVLHGGIPQLRRLDIYREFCRKQHVILITTDLACRGL 848

Query: 337 DVQQVSLVINYDLPTNRENYIH 358
           D   V+ VI  D P +   YIH
Sbjct: 849 DFPAVNWVIQLDCPVDVNTYIH 914
>31899
          Length = 453

 Score = 97.8 bits (242), Expect = 7e-21,   Method: Compositional matrix adjust.
 Identities = 55/115 (47%), Positives = 74/115 (64%), Gaps = 1/115 (0%)
 Frame = -1

Query: 28  NEIVDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFA 87
           +E VD F  + LS+ +L G+   GFE+PS IQ +AI     G D+I QA+SGTGKT  F+
Sbjct: 354 SESVD-FASLLLSKPVLNGLKNAGFERPSPIQLKAIPLGRCGLDLIVQAKSGTGKTCVFS 178

Query: 88  ISILQQIELDLKATQALVLAPTRELAQQIQKVVMALGDYM-GASCHACIGGTNVR 141
           +  L+ IE   ++TQ LVLAPTRE+A QI +V+ ++G  M G  CH  IGG  V 
Sbjct: 177 VVALEGIETTARSTQVLVLAPTREIALQIWEVINSIGSAMSGLQCHTFIGGLPVH 13
>11160
          Length = 646

 Score = 75.1 bits (183), Expect(2) = 9e-18,   Method: Compositional matrix adjust.
 Identities = 53/189 (28%), Positives = 92/189 (48%), Gaps = 15/189 (7%)
 Frame = -1

Query: 136 GGTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRR------YLSPKYIKMFVLDEADEMLS 189
           GG +   ++ K       I++ TPGR+ D+ +R+        S K +++ VLDEAD +L 
Sbjct: 646 GGVSCSHDISKFMKSGGSILIATPGRLDDLFSRKESGFNLAASVKALEVLVLDEADRLLD 467

Query: 190 RGFKDQIYDIFQKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEELTLEG---- 245
            GF+  I  I   L    +  L SAT   +V  + +  +R+P+R+ VK+++L  E     
Sbjct: 466 MGFEASINTILGHLPKLRRTGLFSATQTDEVENLIRAGLRNPLRVTVKEKKLAGEADQRT 287

Query: 246 ---IRQFYINVEREEWKLDTLCDLYETLTITQAVIFINTRRKVDWLTEKMHA--RDFTVS 300
              +  +Y+ VE EE K   L    +T    + ++F +T   VD+ +  +    +   V 
Sbjct: 286 PSTLSNYYMIVEAEE-KFSQLVKFLKTHHRDKLLLFFSTCACVDYFSMCLTQLLKHMQVL 110

Query: 301 AMHGDMDQK 309
           ++H  M QK
Sbjct: 109 SIHSKMKQK 83

 Score = 33.1 bits (74), Expect(2) = 9e-18,   Method: Compositional matrix adjust.
 Identities = 13/31 (41%), Positives = 22/31 (70%)
 Frame = -3

Query: 307 DQKERDVIMREFRSGSSRVLITTDLLARGID 337
           D+ E   +  +FRS +S +L+ TD++ARG+D
Sbjct: 95  DEAEEKPVFAKFRSITSGLLVCTDVMARGVD 3
>22006
          Length = 3414

 Score = 86.7 bits (213), Expect = 2e-17,   Method: Compositional matrix adjust.
 Identities = 47/135 (34%), Positives = 78/135 (57%), Gaps = 1/135 (0%)
 Frame = +2

Query: 55   PSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISILQQIEL-DLKATQALVLAPTRELA 113
            P+ IQ++ I   ++G D++A A++G+GKTA F + +L+++++   K  +AL+L+PTRELA
Sbjct: 3005 PTPIQRKTIPVIMEGKDMVAMARTGSGKTAAFLVPMLERLKMHSSKGARALILSPTRELA 3184

Query: 114  QQIQKVVMALGDYMGASCHACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSP 173
             Q  K    LG ++       +GG  +  +   L  + P II+ TPGR+  +L     S 
Sbjct: 3185 LQTLKFTKELGKFLDLRAAVILGGDRMEDQFSALH-QNPDIIIATPGRLLHVLVEMKKSL 3361

Query: 174  KYIKMFVLDEADEML 188
            K +   V DEAD + 
Sbjct: 3362 KEVIYVVFDEADRLF 3406
>19525
          Length = 585

 Score = 85.5 bits (210), Expect = 3e-17,   Method: Compositional matrix adjust.
 Identities = 49/154 (31%), Positives = 84/154 (54%), Gaps = 1/154 (0%)
 Frame = +2

Query: 101 TQALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTNVRAEVQKLQMEAPHIIVGTPG 160
           T+ LVL PTRELA Q+ +V   +  Y   S     GG +++ +   L++  P I+V TPG
Sbjct: 14  TRVLVLVPTRELAVQVYQVGQQISQYTKISICLAAGGLDIKGQEAALRL-CPDIVVATPG 190

Query: 161 RVFDML-NRRYLSPKYIKMFVLDEADEMLSRGFKDQIYDIFQKLNSNTQVVLLSATMPSD 219
           R+ D L N    +  ++++ VLDEAD ML   F  Q+ +I +  N   Q +L SATM   
Sbjct: 191 RLIDHLHNAPNFTIAHVEILVLDEADRMLDEYFAAQMTEIIRMCNFQRQTMLFSATMSDA 370

Query: 220 VLEVTKKFMRDPIRILVKKEELTLEGIRQFYINV 253
           V ++    +++ +++ V +      G++Q ++ +
Sbjct: 371 VQDLASVSLKEAVKVFVNQNTDIALGLQQEFVRI 472
>14337
          Length = 693

 Score = 84.0 bits (206), Expect = 1e-16,   Method: Compositional matrix adjust.
 Identities = 47/144 (32%), Positives = 70/144 (48%)
 Frame = +2

Query: 256 EEWKLDTLCDLYETLTITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIM 315
           E  KL  + +L+        ++F+ ++++   L  +       V A+H D  Q ERD  +
Sbjct: 8   EAGKLMAMRNLFTEGITPPVLVFVQSKQRAKELYSEFMFDKHKVDAIHADKPQAERDATV 187

Query: 316 REFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHXXXXXXXXXXXXVAINM 375
           R F  G   VL+ T+L+ RGID + ++LVINYD PTN  +YIH             AI  
Sbjct: 188 RAFTEGRVWVLVCTELMGRGIDFKGINLVINYDFPTNAVSYIHRIGRTGRAGVPGRAITF 367

Query: 376 VTEEDKRTLRDIETFYNTSIEEMP 399
            TE+D   LR I      +  E+P
Sbjct: 368 FTEQDVTHLRSIANIIKEAGCEVP 439
>08036
          Length = 1226

 Score = 60.5 bits (145), Expect(2) = 7e-15,   Method: Compositional matrix adjust.
 Identities = 45/180 (25%), Positives = 92/180 (51%), Gaps = 4/180 (2%)
 Frame = +1

Query: 155 IVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRGFKDQIYDIFQKLNSNTQVVLLSA 214
           +VGTP R+   L   +L    ++M V+DEAD + S G +  +  + ++L    Q  L+SA
Sbjct: 1   VVGTPSRILAHLRAGHLELHTVQMLVVDEADLVFSFGHEADMKKLMEELPRIYQAFLMSA 180

Query: 215 TMPSDVLEVTKKFMRDPIRILVKKEELTLEG-IRQFYINVEREEWKLDTLCDLYETLTIT 273
           T+  DV  + K  + +P+ + +K+ +L     + Q+++  E ++     +  L   L   
Sbjct: 181 TLSEDVKALKKMVLHNPVILKLKESQLPESTQLTQYHVKCEVDDKFTLMVAVLKLGLVRG 360

Query: 274 QAVIFINTRRKVDWLTE-KMHARDFTVSA--MHGDMDQKERDVIMREFRSGSSRVLITTD 330
           ++++F+N+   VD   + K+    F + A  ++ ++  K R  I+ +F  G   ++I +D
Sbjct: 361 KSILFVNS---VDSCYKLKLFLEPFGIPACVLNSELPVKSRCHIVSQFNEGLYDIIIASD 531

 Score = 37.7 bits (86), Expect(2) = 7e-15,   Method: Compositional matrix adjust.
 Identities = 17/57 (29%), Positives = 28/57 (49%)
 Frame = +3

Query: 332 LARGIDVQQVSLVINYDLPTNRENYIHXXXXXXXXXXXXVAINMVTEEDKRTLRDIE 388
           +ARGID Q VS VIN++ P   + YIH             A+++++  +      +E
Sbjct: 609 VARGIDFQNVSNVINFEFPKTVDAYIHRVGRTARGDKQGCALSLISRHENDQFEAVE 779
>34295
          Length = 694

 Score = 70.5 bits (171), Expect = 1e-12,   Method: Compositional matrix adjust.
 Identities = 45/131 (34%), Positives = 64/131 (48%), Gaps = 1/131 (0%)
 Frame = -1

Query: 272 ITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREFRSGSSRVLITTDL 331
           I   +IF NT++    L+  +   +     +HG M QKER   +  F+S   R LI TD+
Sbjct: 544 IPNVMIFTNTKKYCQLLSMTLTNMEIENVCLHGFMRQKERVSALSRFKSNHIRTLIATDV 365

Query: 332 LARGIDVQQVSLVINYDLPTNRENYIHXXXXXXXXXXXXVAINMVT-EEDKRTLRDIETF 390
            ARG+D+  V LVIN+ LP   + YIH            VAI++     D   L  IE  
Sbjct: 364 AARGLDIPSVQLVINHMLPRTPKEYIHRVGRTARAGRKGVAISIFRFPRDLELLGAIEEE 185

Query: 391 YNTSIEEMPLN 401
            NT + E P++
Sbjct: 184 INTKLTEHPID 152
>00617
          Length = 1505

 Score = 69.3 bits (168), Expect = 3e-12,   Method: Compositional matrix adjust.
 Identities = 31/110 (28%), Positives = 63/110 (57%)
 Frame = -3

Query: 297  FTVSAMHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENY 356
            F+ + +H  + Q+ R   +  F+S  +R+LI+TD+ +RG+D+  V L+IN+++P    +Y
Sbjct: 1482 FSCAVLHSMIPQRFRLSSLSRFKSNQTRILISTDVASRGLDIPTVDLIINHNIPNRPRDY 1303

Query: 357  IHXXXXXXXXXXXXVAINMVTEEDKRTLRDIETFYNTSIEEMPLNVADLI 406
            +H             +I++VTE D + ++ IE+  N  + E P+   +++
Sbjct: 1302 VHRVGRTARAGRCGQSISLVTEFDIKLIKSIESHINCQMTEHPVKEKEVL 1153
>33025
          Length = 558

 Score = 62.8 bits (151), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 41/155 (26%), Positives = 76/155 (49%), Gaps = 6/155 (3%)
 Frame = +3

Query: 128 GASCHACI--GGTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEAD 185
           G   H  +  G T+ R +  ++ M+  +++VGTPGR+ D +  + +S    +  +LDEAD
Sbjct: 33  GTDVHPSVVYGATDRRYQKSRI-MKGANLVVGTPGRLLDFIGDQTISLGKCQYLILDEAD 209

Query: 186 EMLSRGFKDQIYDIFQKLN----SNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEEL 241
            ML  GF+ +I  +         +  Q ++ SAT   D+  +   F+ D + I V     
Sbjct: 210 RMLDMGFEPEIRKLVDTHGMPPKTQRQTLMFSATFKEDIQRLAGDFLNDYLFITVGIVGG 389

Query: 242 TLEGIRQFYINVEREEWKLDTLCDLYETLTITQAV 276
               + Q ++ V+R + K D LC++   +   ++V
Sbjct: 390 ACSDVTQTFLEVDRLQ-KRDHLCEILNEMGTAKSV 491
>19172
          Length = 484

 Score = 62.0 bits (149), Expect = 4e-10,   Method: Compositional matrix adjust.
 Identities = 24/64 (37%), Positives = 43/64 (67%)
 Frame = -1

Query: 273 TQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREFRSGSSRVLITTDLL 332
           T+ +IF+ T+++VD +T  +  + +   A+HGD  Q+ERD ++  FR+G   +L+ TD+ 
Sbjct: 334 TKTIIFVETKKRVDEITRNISRQGWRACAIHGDKSQQERDFVLSSFRNGRHSILVATDVA 155

Query: 333 ARGI 336
           ARG+
Sbjct: 154 ARGL 143
>12995
          Length = 1072

 Score = 60.5 bits (145), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 29/124 (23%), Positives = 59/124 (47%)
 Frame = +3

Query: 276 VIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREFRSGSSRVLITTDLLARG 335
           V+F+ T+  V++L   +       + ++  +DQ  R + + +F     +V++ TDL ARG
Sbjct: 141 VVFVATKHHVEYLNTLLTKCGIACTYIYSSLDQTARKIHVAKFTHKQVKVMLVTDLAARG 320

Query: 336 IDVQQVSLVINYDLPTNRENYIHXXXXXXXXXXXXVAINMVTEEDKRTLRDIETFYNTSI 395
           ID+ Q+  V+N+  P   + ++H             A ++V  ++   L D+  F    +
Sbjct: 321 IDIPQLDNVVNFHFPAKAKLFVHRVGRVARAGRSGTAYSLVAMDEVAHLVDLHVFLGRPL 500

Query: 396 EEMP 399
           +  P
Sbjct: 501 KTAP 512
>17708
          Length = 882

 Score = 58.2 bits (139), Expect = 7e-09,   Method: Compositional matrix adjust.
 Identities = 35/100 (35%), Positives = 59/100 (59%), Gaps = 4/100 (4%)
 Frame = +1

Query: 71  DVIAQAQSGTGKTATF---AISILQQIE-LDLKATQALVLAPTRELAQQIQKVVMALGDY 126
           D++  A++G+GKT  F   AI ++ +++ +    T  ++++PTREL+ Q   V+  L  Y
Sbjct: 556 DLMGAAKTGSGKTLAFLIPAIELMYKLKFMPRNGTGCIIISPTRELSMQTFNVLTELLKY 735

Query: 127 MGASCHACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFDML 166
              +    +GG N   EV+KL+ +  +IIV TPGR+ D L
Sbjct: 736 HHHTFGLIMGGVNRHDEVKKLK-KGVNIIVATPGRLLDHL 852
>17544
          Length = 1047

 Score = 57.0 bits (136), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 41/136 (30%), Positives = 68/136 (50%), Gaps = 19/136 (13%)
 Frame = +2

Query: 31  VDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISI 90
           ++SF++  L E +   I    + KP+ +Q+ A+   +   D++A AQ+G+GKTA F + I
Sbjct: 629 INSFEECTLGEIIRNNIVLSKYNKPTPVQKFALPIVLGKRDLMACAQTGSGKTAAFLLPI 808

Query: 91  LQQIELD------LKATQ-----------ALVLAPTRELAQQIQKVVMALGDYMGASCHA 133
           L Q+  +      L+  Q           AL+LAPTRELA QI            +    
Sbjct: 809 LNQVYENGPTPEALQQNQSRGYRRKMYPIALILAPTRELASQIYDEARKFA--YRSRLRP 982

Query: 134 CI--GGTNVRAEVQKL 147
           C+  GG ++ A+++ L
Sbjct: 983 CVVYGGADIGAQMRDL 1030
>30136
          Length = 524

 Score = 56.2 bits (134), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 41/128 (32%), Positives = 66/128 (51%), Gaps = 7/128 (5%)
 Frame = +2

Query: 28  NEIVDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFA 87
           N I D F +  L + +++ I   G++ P+ IQ +     + G + +  A++G+GKT  + 
Sbjct: 122 NPIQD-FAEAYLPDYVIKEIRRQGYKSPTPIQAQGWPIAMSGANFVGIAKTGSGKTLGYI 298

Query: 88  ISIL-----QQIELDLKATQALVLAPTRELAQQIQKVVMALG--DYMGASCHACIGGTNV 140
           +  +     QQ     +   ALVLAPTRELAQQIQ+V    G   Y+  +C    GG   
Sbjct: 299 LPAIVHINNQQPLQRGEGPIALVLAPTRELAQQIQQVATEFGSSSYVRNTC--VFGGAPK 472

Query: 141 RAEVQKLQ 148
             +++ LQ
Sbjct: 473 GGQMRDLQ 496
>10649
          Length = 472

 Score = 52.4 bits (124), Expect = 4e-07,   Method: Compositional matrix adjust.
 Identities = 27/70 (38%), Positives = 37/70 (52%)
 Frame = +1

Query: 289 TEKMHARDFTVSAMHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYD 348
           +++  A   +V  +HG + Q  R  I REF      +LITTDL  RG+D   V+ VI  D
Sbjct: 43  SDQARAAGMSVLVLHGGIPQLRRLDIYREFCRKQHVILITTDLACRGLDFPAVNWVIQLD 222

Query: 349 LPTNRENYIH 358
            P +   YIH
Sbjct: 223 CPVDVNTYIH 252
>19151
          Length = 625

 Score = 52.0 bits (123), Expect = 4e-07,   Method: Compositional matrix adjust.
 Identities = 30/88 (34%), Positives = 49/88 (55%), Gaps = 7/88 (7%)
 Frame = -3

Query: 324 RVLITTDLLARGIDVQQVSLVINYDLP------TNRENYIHXXXXXXXXXXXXVAINMV- 376
           +VLITT++L+RGID++QV++V+N+DLP       + E Y+H            +AIN++ 
Sbjct: 623 KVLITTNVLSRGIDIEQVTIVVNFDLPIDLRGNADCETYLHRIGRTGRFGKSGIAINLID 444

Query: 377 TEEDKRTLRDIETFYNTSIEEMPLNVAD 404
            E+     R IE  +   I  +  + AD
Sbjct: 443 GEKSMNVCRAIEKHFQKDIVYLNTDNAD 360
>11624
          Length = 2257

 Score = 49.3 bits (116), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 41/166 (24%), Positives = 75/166 (45%), Gaps = 6/166 (3%)
 Frame = -1

Query: 242 TLEGIRQFYINVEREEWKLDTLCDLYETLTITQAVIFINTRRKVD--WLTEKMHARDFTV 299
           T EG+ ++ +  +  E  L  L  L+  L     + F N+        L  K++    +V
Sbjct: 991 TPEGLTEYIVESDSSEKPLLVLHFLH-NLKFRSVLCFTNSVETTHRLCLLVKLYG-GLSV 818

Query: 300 SAMHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHX 359
                 +  + R  I+++F  G   +L+ +D +ARG+DV  V  VI+YD P   + YIH 
Sbjct: 817 KEFSSRLPGERRKKILKQFSKGKIDLLVCSDAMARGMDVDNVKYVISYDNPPYIKTYIHR 638

Query: 360 XXXXXXXXXXXVAINMVTEED----KRTLRDIETFYNTSIEEMPLN 401
                       AI+++ +++    K+ +R+   +    I+EM L 
Sbjct: 637 VGRTARAGRAGTAISLLEKKEFFHFKQMMREAGKW--KKIKEMKLG 506
>39583
          Length = 234

 Score = 46.2 bits (108), Expect = 2e-05,   Method: Composition-based stats.
 Identities = 17/44 (38%), Positives = 31/44 (70%)
 Frame = -3

Query: 315 MREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIH 358
           ++ F+ G   VL+ TDL +RG+D++ V  VIN+ +P+  ++Y+H
Sbjct: 160 LKRFKEGEIDVLLATDLASRGLDIEGVKTVINFTMPSTLKHYVH 29
>31781
          Length = 416

 Score = 42.0 bits (97), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 16/50 (32%), Positives = 33/50 (66%)
 Frame = -2

Query: 230 DPIRILVKKEELTLEGIRQFYINVEREEWKLDTLCDLYETLTITQAVIFI 279
           +P+ I +++EE +L+ I+Q+YI       K   LC++Y ++++ Q++IF 
Sbjct: 277 NPVTIRLRREEESLDNIQQYYIRCRTLSDKYRALCNIYGSISVGQSMIFC 128
>12121
          Length = 465

 Score = 35.8 bits (81), Expect = 0.028,   Method: Compositional matrix adjust.
 Identities = 17/39 (43%), Positives = 21/39 (53%)
 Frame = -3

Query: 154 IIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRGF 192
           I + TPGR+ D L     + +     VLDEAD ML  GF
Sbjct: 463 ICIATPGRLIDFLESNRTNLRRCTYLVLDEADRMLDMGF 347
>31220
          Length = 818

 Score = 33.9 bits (76), Expect = 0.11,   Method: Compositional matrix adjust.
 Identities = 14/26 (53%), Positives = 19/26 (73%)
 Frame = +2

Query: 333 ARGIDVQQVSLVINYDLPTNRENYIH 358
           +RGID Q V+ VIN+D P +  +YIH
Sbjct: 164 SRGIDFQGVNNVINFDFPLDVTSYIH 241
>33083
          Length = 1931

 Score = 32.0 bits (71), Expect = 0.44,   Method: Compositional matrix adjust.
 Identities = 11/25 (44%), Positives = 16/25 (64%)
 Frame = +1

Query: 334 RGIDVQQVSLVINYDLPTNRENYIH 358
           RG+D+ QV  ++ YD P   + YIH
Sbjct: 1   RGLDIPQVDWIVQYDPPDESKEYIH 75
>10351
          Length = 575

 Score = 32.0 bits (71), Expect = 0.45,   Method: Compositional matrix adjust.
 Identities = 16/38 (42%), Positives = 22/38 (57%)
 Frame = +2

Query: 22  VIESNWNEIVDSFDDMNLSESLLRGIYAYGFEKPSAIQ 59
           V + +W+   D+FDD NL    LRG+Y YG     AI+
Sbjct: 74  VKKVHWDCAWDTFDDSNL----LRGVYEYGMGSWEAIR 175
>06438
          Length = 989

 Score = 31.2 bits (69), Expect = 0.84,   Method: Compositional matrix adjust.
 Identities = 13/32 (40%), Positives = 17/32 (53%)
 Frame = +1

Query: 327 ITTDLLARGIDVQQVSLVINYDLPTNRENYIH 358
           +T  L  RG+D   V+ VI  D P +   YIH
Sbjct: 25  LTVTLACRGLDFPAVNWVIQLDCPVDVNTYIH 120
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31982472|ref|NP_031664.2| chaperonin containing Tcp1,
subunit 7 (eta) [Mus musculus]
         (544 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

09900                                                                 519   e-153
01159                                                                 239   3e-63
05356                                                                 115   2e-50
06409                                                                 152   5e-37
12796                                                                 132   3e-31
29864                                                                 122   4e-28
29631                                                                 110   2e-24
33770                                                                  92   7e-19
30661                                                                  79   4e-15
17249                                                                  63   4e-10
25058                                                                  32   0.81 
02673                                                                  29   4.0  
>09900
          Length = 1305

 Score =  519 bits (1337), Expect(2) = e-153,   Method: Compositional matrix adjust.
 Identities = 243/308 (78%), Positives = 277/308 (89%)
 Frame = +3

Query: 233 KNPKIALLNVELELKAEKDNAEIRVHTVEDFQAIVDAEWNILYDKLEKIHQSGAKVILSK 292
           + P+IALLN+ELELK+E+DNAE+RV  V+++Q+IVDAEW ILYDKL+KIHQSGAKV+LSK
Sbjct: 51  RTPRIALLNIELELKSERDNAEVRVDNVQEYQSIVDAEWKILYDKLDKIHQSGAKVVLSK 230

Query: 293 LPIGDVATQYFADRDMFCAGRVPEEDLKRTMMACGGSIQTSVNALVPDVLGHCQVFEETQ 352
           LPIGDVATQYFADRDMFCAGRVPEEDL+RTM ACGGSIQT+V +L PDVLG CQ+F+E Q
Sbjct: 231 LPIGDVATQYFADRDMFCAGRVPEEDLRRTMKACGGSIQTTVQSLTPDVLGTCQLFDEIQ 410

Query: 353 IGGERYNFFTGCPKAKTCTIILRGGAEQFMEETERSLHDAIMIVRRAIKNDSVVAGGGAI 412
           IGGER+N F GC  A+TCTIILRGGAEQFMEETERSLHDAIMIVRRAIKNDSVVAGGGAI
Sbjct: 411 IGGERFNMFKGCTMARTCTIILRGGAEQFMEETERSLHDAIMIVRRAIKNDSVVAGGGAI 590

Query: 413 EMELSKYLRDYSRTIPGKQQLLIGAYAKALEIIPRQLCDNAGFDATNILNKLRARHAQGG 472
           EME+S +LR++S TI GK+QLL+ AYAKALE+IPRQLCDNAGFDATNILNKLR +HAQGG
Sbjct: 591 EMEVSYHLREHSHTIAGKEQLLMSAYAKALEVIPRQLCDNAGFDATNILNKLRQKHAQGG 770

Query: 473 MWYGVDINNENIADNFQAFVWEPAMVRINALTAASEAACLIVSVDETIKNPRSTVDPPAP 532
            WYGV+I  E+IADNF+  VWEPA+V+INALTAASEA  LI+SVDETIKNPRS     AP
Sbjct: 771 TWYGVNILREDIADNFEDCVWEPAVVKINALTAASEATALILSVDETIKNPRSG-QGDAP 947

Query: 533 SAGRGRGQ 540
            AGRGRG+
Sbjct: 948 GAGRGRGR 971

 Score = 40.4 bits (93), Expect(2) = e-153,   Method: Compositional matrix adjust.
 Identities = 16/20 (80%), Positives = 17/20 (85%)
 Frame = +1

Query: 217 KKTFSYAGFEMQPKKYKNPK 236
           KKTFSYAGFEMQPK Y  P+
Sbjct: 1   KKTFSYAGFEMQPKAYSGPQ 60
>01159
          Length = 2613

 Score =  239 bits (609), Expect = 3e-63,   Method: Compositional matrix adjust.
 Identities = 157/528 (29%), Positives = 278/528 (52%), Gaps = 9/528 (1%)
 Frame = +3

Query: 5   PVILLKEGTDSSQ--GIPQLVSNISACQVIAEAVRTTLGPRGMDKLIVDGRGKATISNDG 62
           P I+L++    S+  GI    S+I A + +A  ++T+LGP+G+DK++V G G  T++NDG
Sbjct: 135 PFIILRDQDKKSRLTGIEAHKSHILAAKSVASILKTSLGPKGLDKMMVSGDGDVTVTNDG 314

Query: 63  ATILKLLDVVHPAAKTLVDIAKSQDAEVGDGTTSVTLLAAEFLKQVKPYVEEGLHPQIII 122
           ATIL ++DV H  AK +V ++KSQD E+GDGTT V +LA   L+Q +  ++ G+HP  I 
Sbjct: 315 ATILDMMDVDHQIAKLMVQLSKSQDDEIGDGTTGVVVLAGALLEQAEKLLDRGIHPIRIA 494

Query: 123 RAFRTATQLAVNKIKEIAVTVKKQDKVEQRKMLEKCAMTALSSKLISQQKVFFAKMVVDA 182
             +  A + AV  + +I+   +    ++  + L K AMT L SK++++     AK+ VDA
Sbjct: 495 DGYEIAAKCAVETLDKISDNYEVD--LKNAEPLIKLAMTTLGSKIVNRCHRQMAKIAVDA 668

Query: 183 VMMLDEL----LQLKMIGIKKVQGGALEESQLVAGVAFKKTFSYAGFEMQPKKYKNPKIA 238
           +M + +L    +  ++I ++   GG LE++ LV GV   K  S+      PK  K+ KIA
Sbjct: 669 IMSVADLKRKDVDFELIKVEGKVGGKLEDTMLVKGVVVDKDMSHPQM---PKVVKDAKIA 839

Query: 239 LLNVELELKAEKDNAEIRVHTVEDFQAIVDAEWNILYDKLEKIHQSGAKVILSKLPIGDV 298
           +L    E    K   ++ + +VED++ + + E N     ++ +   GA +++ +    D 
Sbjct: 840 ILTCPFEPPKPKTKHKLDITSVEDYKKLREYELNKFESMVQSVKDKGANLVICQWGFDDE 1019

Query: 299 ATQYFADRDMFCAGRVPEEDLKRTMMACGGSIQTSVNALVPDVLGHCQVFEETQIGG--E 356
           A      R++     V   +++   +A GG I      L  + LG   +  E   G   +
Sbjct: 1020ANHLLLQRELPAVRWVGGPEIELIAIATGGRIVPRFEELTTEKLGKAGIVRELTFGTTKD 1199

Query: 357 RYNFFTGCPKAKTCTIILRGGAEQFMEETERSLHDAIMIVRRAIKNDSVVAGGGAIEMEL 416
           R      C   +  TI +RGG +  +EE +RSLHDA+ ++R  ++++ VV GGGA E+  
Sbjct: 1200RMLVIEECLNTRAVTIFIRGGNKMIVEEAKRSLHDALCVIRNLVRDNRVVYGGGAPEIAA 1379

Query: 417 SKYLRDYSRTIPGKQQLLIGAYAKALEIIPRQLCDNAGFDATNILNKLRARHA-QGGMWY 475
           S  + + +  I   +Q  + ++++ALE +P  L +N+G      L ++++R   +     
Sbjct: 1380SVAVAEAADKISTLEQYAVRSFSEALEAVPLALAENSGLAPIQTLAEVKSRQVKEKNPRL 1559

Query: 476 GVDINNENIADNFQAFVWEPAMVRINALTAASEAACLIVSVDETIKNP 523
           G+D   +   D  +  V E    +   +  A++   +I+ +D+ I+ P
Sbjct: 1560GIDCLLKGTNDMKEQNVIETLTAKKQQILLATQLVRMILKIDD-IRAP 1700
>05356
          Length = 2339

 Score =  115 bits (287), Expect(2) = 2e-50,   Method: Compositional matrix adjust.
 Identities = 70/228 (30%), Positives = 120/228 (52%), Gaps = 2/228 (0%)
 Frame = +1

Query: 295  IGDVATQYFADRDMFCAGRVPEEDLKRTMMACGGSIQTSVNALVPDVLGHCQVFEETQIG 354
            +GD+A  Y     +     + + DL+R   +   +    V     +  G+C +    +IG
Sbjct: 1078 VGDLAQHYCNKYKVMVIRLLSKWDLRRLCKSICATALPKVTTPRNEECGYCDLVYVDEIG 1257

Query: 355  GERYNFFT-GCPKAKTCTIILRGGAEQFMEETERSLHDAIMIVRRAIKNDSVVAGGGAIE 413
                  F     ++   T+I+RG  +  M++ ER+L D +   +   K+D +V G GA E
Sbjct: 1258 ETPVVIFQQNKDESPITTVIIRGSTDNIMDDIERALDDGVNTFKALTKDDRLVPGAGATE 1437

Query: 414  MELSKYLRDYSRTIPGKQQLLIGAYAKALEIIPRQLCDNAGFDATNILNKLRARHAQGGM 473
            +EL+K +  Y  ++PG +Q  +  +A++LE+IPR L +N G  AT+IL+KL A H +G  
Sbjct: 1438 IELAKQITTYGESLPGLEQYAVKKFAESLEVIPRALAENTGMKATDILSKLYAAHQEGQQ 1617

Query: 474  WYGVDINNE-NIADNFQAFVWEPAMVRINALTAASEAACLIVSVDETI 520
              GVDI++  ++ D  QA + +  + R   L  A+ AAC ++ VD+ I
Sbjct: 1618 NAGVDIDDSGSVLDAKQANLTDLYLNRYWGLKFAAAAACTVLRVDQII 1761

 Score =  102 bits (255), Expect(2) = 2e-50,   Method: Compositional matrix adjust.
 Identities = 78/292 (26%), Positives = 147/292 (50%), Gaps = 8/292 (2%)
 Frame = +2

Query: 8   LLKEGTDSSQGIPQLV-SNISACQVIAEAVRTTLGPRGMDKLIVDGRGKATISNDGATIL 66
           +LK+G     G+ + V  NI AC+ +A+  R+  GP G +K++++   K  ++ND ATIL
Sbjct: 230 MLKDGAKHFSGLDEAVYRNIEACKELAKTTRSAYGPHGQNKMVINHLEKLFVTNDAATIL 409

Query: 67  KLLDVVHPAAKTLVDIAKSQDAEVGDGTTSVTLLAAEFLKQVKPYVEEGLHPQIIIRAFR 126
           + L+V HPAAK LV  A  Q+ E GDGT  V + A   L+  +  +  GL    +I  + 
Sbjct: 410 RELEVQHPAAKMLVLAAHQQEQECGDGTNFVLVFAGALLENAEQLLRMGLSVTEVIEGYE 589

Query: 127 TATQLAVNKIKEIAV-TVKKQDKVEQRKMLEKCAMTALSSKLISQQ---KVFFAKMVVDA 182
            A + A   + ++ +  VK     E+ K       TA+ + ++S+Q   + F A ++ DA
Sbjct: 590 LALKKAHEILPKLVIGHVKNLRNKEEVK-------TAIRTSVMSKQYGNEDFLADLITDA 748

Query: 183 -VMMLDELLQLKMIGIK--KVQGGALEESQLVAGVAFKKTFSYAGFEMQPKKYKNPKIAL 239
            V +L   +   +  ++  K+ G  L +S  + G+ FK+       E +  K +  K+A+
Sbjct: 749 CVSVLPAKISFSVDNVRVCKILGCGLLQSSTIQGMVFKRQ-----VEGEITKVEKAKVAV 913

Query: 240 LNVELELKAEKDNAEIRVHTVEDFQAIVDAEWNILYDKLEKIHQSGAKVILS 291
               L+    +    + +   E+  +    E +++ ++++ I ++G  VI++
Sbjct: 914 FTCPLDSMQTETKGTVLIKNAEELMSFSKGEEDMMEEQIKGIKEAGVNVIVA 1069
>06409
          Length = 1533

 Score =  152 bits (383), Expect = 5e-37,   Method: Compositional matrix adjust.
 Identities = 92/316 (29%), Positives = 158/316 (50%), Gaps = 12/316 (3%)
 Frame = -3

Query: 229  PKKYKNPKIALLNVELELKAEKDNAEIRVHTVEDFQAIVDAEWNILYDKLEKIHQSGAKV 288
            P K +  KI  +   +         ++ V        ++  E N + D ++KI ++G  V
Sbjct: 1501 PSKVEKAKIGFIQFCISPPKTDMENQVIVSDYTQMDRVLREERNYILDIVKKIKKAGCNV 1322

Query: 289  ILSKLPI-----GDVATQYFADRDMFCAGRVPEEDLKRTMMACGGSIQTSVNALVPDVLG 343
            +L +  I      D+A  + A   +     +  ED++      G     S++  +P+ LG
Sbjct: 1321 LLIQKSILRDAVSDLALHFLAKMKIMVVKDIEREDVEFVCKTLGCRPVASLDHFLPENLG 1142

Query: 344  HCQVFEETQIGGERYNFFTGCPK-AKTCTIILRGGAEQFMEETERSLHDAIMIVRRAIKN 402
               + EE Q G  +    TG     +T T+++RG  +  +EE +RSLHDA+ ++R  +K 
Sbjct: 1141 SADLIEEVQTGSSKIVKATGIANPGQTVTVLIRGSNKLVLEEADRSLHDALCVIRCLVKK 962

Query: 403  DSVVAGGGAIEMELSKYLRDYSRTIPGKQQLLIGAYAKALEIIPRQLCDNAGFDATNILN 462
             +++AGGGA E E+S  L  Y+ T+ G +Q    A+A+ALE+IP  L +NAG +  + + 
Sbjct: 961  KALIAGGGAPETEMSMRLAAYANTLAGMEQYCFRAFAEALEVIPFTLAENAGLNPISTVT 782

Query: 463  KLRARHAQGGMWYGVDINNENIADNFQAFVWEPAMVRINALTAASEAACLIVSVDETIKN 522
             LR RHAQG    G+++    I +  +  V +P +V  +A+T ASE    I+ +D+ +  
Sbjct: 781  XLRTRHAQGERTAGINVRKGAITNILEENVLQPLLVSTSAITLASETVRSILKIDDIVNC 602

Query: 523  PRS------TVDPPAP 532
             RS       +DP +P
Sbjct: 601  VRS*SASKVLLDPHSP 554
>12796
          Length = 1316

 Score =  132 bits (333), Expect = 3e-31,   Method: Compositional matrix adjust.
 Identities = 102/348 (29%), Positives = 177/348 (50%), Gaps = 10/348 (2%)
 Frame = -3

Query: 190  LQLKMIGIKKVQGGALEESQLVAGVAFKKTFSYAGFEMQPKKYKNPKIALLNVELELKAE 249
            + LK I + +  GG +E+++LV G+ F  T   AG    PK+ +  KI L  ++  + A 
Sbjct: 1308 VDLKNIKVIRSLGGTVEDTELVNGLVF--TSRSAGTN-APKRIEKAKIGL--IQFCISAP 1144

Query: 250  KDNAEIRVHTVEDFQA---IVDAEWNILYDKLEKIHQSGAKVILSKLPI-----GDVATQ 301
            K + +  V  V D+ A   ++  E + + + +++I ++G  V+L +  I      D+A Q
Sbjct: 1143 KTDMDHNV-IVSDYAAMDRVLKEERSYILNIVKQIKKAGCNVLLVQKSILRDAVSDLA-Q 970

Query: 302  YFADR-DMFCAGRVPEEDLKRTMMACGGSIQTSVNALVPDVLGHCQVFEETQIGGERYNF 360
            +F D+        V  ED++            S++    + +    + EE   G  ++  
Sbjct: 969  HFLDKIKCLVVKDVEREDIEFVCKTLHCRPIASLDHFTAENMSSADLVEEVASGTNKFVK 790

Query: 361  FTGCP-KAKTCTIILRGGAEQFMEETERSLHDAIMIVRRAIKNDSVVAGGGAIEMELSKY 419
             TG   + +T +II RG  +  +EE  RSLHDA+ +VR  ++N + + GGGA E+E++  
Sbjct: 789  ITGIQNQGRTVSIICRGSNKLVLEEAARSLHDALCVVRCLVRNRAQIVGGGAPEIEMALQ 610

Query: 420  LRDYSRTIPGKQQLLIGAYAKALEIIPRQLCDNAGFDATNILNKLRARHAQGGMWYGVDI 479
            L   ++T+ G       A+A ALE+IP  L +NAG +    + +LR RHAQG    G+++
Sbjct: 609  LAAAAQTVDGVDAYCYRAFADALEVIPSTLAENAGLNPIATVTELRNRHAQGEKNAGINV 430

Query: 480  NNENIADNFQAFVWEPAMVRINALTAASEAACLIVSVDETIKNPRSTV 527
                I D F   V +P +V  +A+T A+E    I+ +D+ +     TV
Sbjct: 429  RKGAITDIFAENVVQPLLVSTSAITLATETVRSILKIDDIVNTYS*TV 286
>29864
          Length = 1026

 Score =  122 bits (306), Expect = 4e-28,   Method: Compositional matrix adjust.
 Identities = 83/266 (31%), Positives = 141/266 (53%), Gaps = 3/266 (1%)
 Frame = +1

Query: 22  LVSNISACQVIAEAVRTTLGPRGMDKLIVDGRGKATISNDGATILKLLDVVHPAAKTLVD 81
           L  NI+A + + + +R+ LGP+G  K++V G G   ++ DG  +L  + + HP A  +  
Sbjct: 166 LAVNIAAAKGLQDVLRSNLGPKGTMKMLVSGAGDIKLTKDGNVLLHEMQIQHPTASLIAR 345

Query: 82  IAKSQDAEVGDGTTSVTLLAAEFLKQVKPYVEEGLHPQIIIRAFRTATQLAVNKIKEIAV 141
           +A +QD   GDGTTS  L+  E LKQ   Y+ EGLHP++I   F    +LA NK  E+  
Sbjct: 346 VATAQDDITGDGTTSNVLIIGELLKQADLYIAEGLHPRLITEGF----ELARNKALEVLE 513

Query: 142 TVKKQDKVEQRKMLEKCAMTALSSKLISQQKVFFAKMVVDAVMMLD---ELLQLKMIGIK 198
            VK + +V+ R+ L + A T+L +K+ ++      + VVDAV+ +    E + L M+ + 
Sbjct: 514 EVKVKREVD-RETLVQVARTSLRTKVHTELADLLTEHVVDAVLAIQXPGEGIDLHMVELM 690

Query: 199 KVQGGALEESQLVAGVAFKKTFSYAGFEMQPKKYKNPKIALLNVELELKAEKDNAEIRVH 258
           ++Q     +S LV G+       +   +   K  K+  I   NV LE +  + N+     
Sbjct: 691 EMQHKTDLDSTLVRGLVMDHGARHPDMK---KHTKDAFILTCNVSLEYEKTEVNSGFFYK 861

Query: 259 TVEDFQAIVDAEWNILYDKLEKIHQS 284
           T ++ + +V+AE   + +++ K H S
Sbjct: 862 TAQEREKLVEAERTFIDERVRKNHCS 939
>29631
          Length = 1257

 Score =  110 bits (274), Expect = 2e-24,   Method: Compositional matrix adjust.
 Identities = 61/167 (36%), Positives = 102/167 (61%), Gaps = 1/167 (0%)
 Frame = +3

Query: 6   VILLKEGTDSSQGIPQLVSNISACQVIAEAVRTTLGPRGMDKLIVDGRGKATISNDGATI 65
           +I+L + T    G    + NI+A + IA+ +RT LGP+ M K+++D  G   ++NDG  I
Sbjct: 3   IIVLNQNTRRESGRKVQLGNIAAGKTIADVIRTCLGPKSMLKMLMDPMGGIVMTNDGNAI 182

Query: 66  LKLLDVVHPAAKTLVDIAKSQDAEVGDGTTSVTLLAAEFLKQVKPYVEEGLHPQIIIRAF 125
           L+ ++V HPAAK+++++A++QD E GDGT SV +LA E L   + ++E+ +HP +II A+
Sbjct: 183 LREINVQHPAAKSMIEVARTQDEETGDGTKSVIILAGEVLSVAEQFLEQQMHPTVIIAAY 362

Query: 126 RTATQLAVNKIK-EIAVTVKKQDKVEQRKMLEKCAMTALSSKLISQQ 171
           R A +  +  ++ +I   +   D+    +ML    +T LS   I QQ
Sbjct: 363 RQALEDTLEVLRTKICTPIDISDR---NQMLN--IVTKLSGHQIHQQ 488

 Score = 61.2 bits (147), Expect(2) = 4e-21,   Method: Compositional matrix adjust.
 Identities = 27/73 (36%), Positives = 42/73 (57%)
 Frame = +3

Query: 348  FEETQIGGERYNFFTGCPKAKTCTIILRGGAEQFMEETERSLHDAIMIVRRAIKNDSVVA 407
             E  +IG + + F   C   K CTI+LRG ++  + E ER+L DA+ + R  + +  +  
Sbjct: 1035 LEVRKIGDDYFTFLVDCKSPKACTILLRGASKDILAEVERNLQDAMNVARNVMIDPHLCP 1214

Query: 408  GGGAIEMELSKYL 420
            GGGA EM L++ L
Sbjct: 1215 GGGASEMALAQAL 1253

 Score = 58.5 bits (140), Expect(2) = 4e-21,   Method: Compositional matrix adjust.
 Identities = 42/192 (21%), Positives = 87/192 (45%), Gaps = 7/192 (3%)
 Frame = +1

Query: 159 AMTALSSKLISQQKVFFAKMVVDAVMML-------DELLQLKMIGIKKVQGGALEESQLV 211
           + + L +K IS+      ++ +DA   +        E+   +   ++K+ GG +EES+++
Sbjct: 454 SQSCLGTKFISKWMDLACQIALDATTTVFMEENGRKEIDIKRYAKVEKIPGGTMEESEVL 633

Query: 212 AGVAFKKTFSYAGFEMQPKKYKNPKIALLNVELELKAEKDNAEIRVHTVEDFQAIVDAEW 271
            G+   K   +   +   ++ +NP+I LL+  LE K  +    I +   EDF  I+  E 
Sbjct: 634 KGIXVNKDVVHXKMK---RRIENPRIMLLDCNLEYKKGESATNIEISKEEDFAKILQLEE 804

Query: 272 NILYDKLEKIHQSGAKVILSKLPIGDVATQYFADRDMFCAGRVPEEDLKRTMMACGGSIQ 331
             +    ++I      +++++  + D+A  +     +    RV + D  R   ACG +I 
Sbjct: 805 EYIRKMCDEIIALKPDLVITEKGVSDLAQHFLLKAGISVLRRVRKTDNNRIARACGATIA 984

Query: 332 TSVNALVPDVLG 343
              + L  + +G
Sbjct: 985 NRTDELKEEDMG 1020
>33770
          Length = 484

 Score = 91.7 bits (226), Expect = 7e-19,   Method: Compositional matrix adjust.
 Identities = 67/165 (40%), Positives = 98/165 (59%), Gaps = 5/165 (3%)
 Frame = +1

Query: 47  KLIVDGRGKATISNDGATILKLLDVVHPAAKTLVDIAKSQDAEVGDGTTSVTLLAAEFLK 106
           K+I    G  TI+NDGATILK + V+HPAAK LV+++K+QD E GDGTT+V +LA   L 
Sbjct: 1   KMIQAANGDVTITNDGATILKQMQVLHPAAKMLVELSKAQDIEXGDGTTTVVVLAGSLLD 180

Query: 107 QVKPYVEEGLHPQIIIRAFRTATQLAVNKIKEIAVTVKKQDKVEQRKMLEKCAMTALSSK 166
                + +G+HP +I  AF    Q A +K  E+   + K  ++  R+ L   A T+L+SK
Sbjct: 181 ASAKLLAKGIHPTMISEAF----QKAASKCVELLDGMVKPLELSDRESLLSSASTSLNSK 348

Query: 167 LISQQKVFFAKMVVDAVM-MLDEL----LQLKMIGIKKVQGGALE 206
           ++SQ     A + VDAV+ ++D      + LK I I K  GG ++
Sbjct: 349 VVSQYSSMLAPIAVDAVLKVIDPATATNVDLKDIKIIKKLGGTID 483
>30661
          Length = 380

 Score = 79.0 bits (193), Expect = 4e-15,   Method: Compositional matrix adjust.
 Identities = 40/124 (32%), Positives = 67/124 (54%)
 Frame = +3

Query: 323 MMACGGSIQTSVNALVPDVLGHCQVFEETQIGGERYNFFTGCPKAKTCTIILRGGAEQFM 382
           + + GG I ++ +      LG C + EE  IG ++   F+G    + CTI+LRG  +Q +
Sbjct: 18  LWSLGGEITSTFDCPEKTKLGQCDLIEEVMIGEDKLIKFSGVALGEACTIVLRGATQQIL 197

Query: 383 EETERSLHDAIMIVRRAIKNDSVVAGGGAIEMELSKYLRDYSRTIPGKQQLLIGAYAKAL 442
           +E  RSLHDA+ ++ + +K    V GGG  EM +++ +   +   PGK+       A A+
Sbjct: 198 DEAXRSLHDALCVLSQTVKETRTVYGGGCSEMLMAEAVSQLAAKTPGKE-------AIAM 356

Query: 443 EIIP 446
           E +P
Sbjct: 357 EALP 368
>17249
          Length = 909

 Score = 62.8 bits (151), Expect = 4e-10,   Method: Compositional matrix adjust.
 Identities = 32/88 (36%), Positives = 48/88 (54%), Gaps = 2/88 (2%)
 Frame = +3

Query: 439 AKALEIIPRQLCDNAGFDATNILNKLRARHAQG--GMWYGVDINNENIADNFQAFVWEPA 496
           ++ALE+I R L  N G +    L  LRA+HAQG    W G+D N  NI D  +  +WEP 
Sbjct: 6   SRALEVISRTLIQNCGANTIRTLTALRAKHAQGQKNTW-GIDGNTGNIVDMAEFGIWEPL 182

Query: 497 MVRINALTAASEAACLIVSVDETIKNPR 524
            V++     A E A L++ +D+ +   +
Sbjct: 183 SVKLQVYKTACETAILLLRIDDIVSGTK 266
>25058
          Length = 1058

 Score = 31.6 bits (70), Expect = 0.81,   Method: Compositional matrix adjust.
 Identities = 15/36 (41%), Positives = 23/36 (63%)
 Frame = +2

Query: 73  HPAAKTLVDIAKSQDAEVGDGTTSVTLLAAEFLKQV 108
           H A+KTL+ I     A V  GTT++T+L+ E +K +
Sbjct: 20  HAASKTLIAICSGS*ASVVHGTTAITVLSIE*IKHL 127
>02673
          Length = 1243

 Score = 29.3 bits (64), Expect = 4.0,   Method: Compositional matrix adjust.
 Identities = 20/94 (21%), Positives = 46/94 (48%), Gaps = 1/94 (1%)
 Frame = +1

Query: 431 QQLLIGAYAKALEIIPRQLCDNAGFDATNILNKLRARHA-QGGMWYGVDINNENIADNFQ 489
           +Q  + ++++ALE +P  L +N+G      L ++++R   +     G+D   +   D  +
Sbjct: 64  EQYAVRSFSEALEAVPLALAENSGLAPIQTLAEVKSRQVKEKNPRLGIDCLLKGTNDMKE 243

Query: 490 AFVWEPAMVRINALTAASEAACLIVSVDETIKNP 523
             V E    +   +  A++   +I+ +D+ I+ P
Sbjct: 244 QNVIETLTAKKQQILLATQLVRMILKIDD-IRAP 342
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6754972|ref|NP_035163.1| poly A binding protein,
cytoplasmic 2 [Mus musculus]
         (628 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

17775                                                                 537   e-153
39438                                                                 120   2e-27
25691                                                                  74   2e-13
17681                                                                  71   1e-12
02343                                                                  67   2e-11
08958                                                                  62   8e-10
11687                                                                  61   2e-09
03744                                                                  59   6e-09
20488                                                                  59   7e-09
16427                                                                  59   7e-09
14258                                                                  55   1e-07
30672                                                                  54   3e-07
13822                                                                  53   4e-07
02140                                                                  52   1e-06
14637                                                                  51   1e-06
28455                                                                  49   6e-06
31310                                                                  49   8e-06
28605                                                                  47   2e-05
13457                                                                  45   2e-05
03200                                                                  46   4e-05
19868                                                                  45   9e-05
01278                                                                  45   1e-04
28652                                                                  44   1e-04
03903                                                                  43   4e-04
15371                                                                  42   8e-04
20169                                                                  42   0.001
33516                                                                  41   0.001
02347                                                                  41   0.001
00029                                                                  41   0.001
00302                                                                  41   0.001
35379                                                                  40   0.003
02064                                                                  40   0.004
31618                                                                  39   0.006
00556                                                                  39   0.007
12506                                                                  39   0.008
02809                                                                  39   0.008
03000                                                                  39   0.009
32386                                                                  37   0.024
03059                                                                  37   0.031
00781                                                                  36   0.053
32733                                                                  36   0.057
09736                                                                  35   0.069
02091                                                                  35   0.071
08670                                                                  35   0.074
23322                                                                  35   0.085
25950                                                                  35   0.095
26197                                                                  35   0.11 
15503                                                                  35   0.12 
03406                                                                  35   0.13 
39789                                                                  35   0.13 
28372                                                                  34   0.20 
10194                                                                  33   0.45 
11019                                                                  32   0.99 
12350                                                                  32   1.0  
25632                                                                  31   1.3  
03097                                                                  31   1.4  
12096                                                                  30   2.7  
11579                                                                  30   2.7  
15931                                                                  30   2.8  
04988                                                                  30   3.7  
23720                                                                  30   4.2  
00741                                                                  29   5.7  
>17775
          Length = 1282

 Score =  537 bits (1383), Expect = e-153,   Method: Compositional matrix adjust.
 Identities = 264/391 (67%), Positives = 311/391 (79%), Gaps = 1/391 (0%)
 Frame = -2

Query: 1    MNSSDPGCPMASLYVGDLHPDVTEAMLYEKFSSAGPILSIRVYRDVITRRSLGYASVNFE 60
            MN+  P  PMASLYVGDLHPDVTEAML+EKFS+AGP+LSIRV RD+ITRRSLGYA VNF+
Sbjct: 1224 MNNPGPSYPMASLYVGDLHPDVTEAMLFEKFSTAGPVLSIRVCRDMITRRSLGYAYVNFQ 1045

Query: 61   QPADAERALDTMNFDVIKGKPVRIMWSQRDPSLRRSGVGNVFIKNLNKTIDNKALYDTFS 120
            QPADAERALDTMNFD +KG+P+RIMWSQRDPS+R+SGVGNVFIKNL+KTIDNKALYDTFS
Sbjct: 1044 QPADAERALDTMNFDTVKGRPIRIMWSQRDPSVRKSGVGNVFIKNLDKTIDNKALYDTFS 865

Query: 121  AFGNILSCKVVSDENGSKGHGFVHFETEEAAERAIEKMNGMLLNDRKVFVGRFKSQKERE 180
            AFGNILSCK+  DE GSKG+GFVHFETEEAA +AI+K+NGMLLN +KV+VGRF  +KER 
Sbjct: 864  AFGNILSCKIACDEQGSKGYGFVHFETEEAARQAIDKVNGMLLNGKKVYVGRFIPRKERI 685

Query: 181  AELGTGTKEFTNVYIKNFGDRMDDETLNGLFGRFGQI-LSVKVMTDEXXXXXXXXXXXXE 239
              +G   K F NVY+KNF           L  +  Q  L       E            E
Sbjct: 684  MMMGDKLKRFNNVYVKNFC*GTG*RPAA*LVWQARQDHLXXGACRGEDGKSRGFGFVSFE 505

Query: 240  RHEDAQKAVDEMNGKELNGKHIYVGRAQKKDDRHTELKHKFEQVTQDKSIRYQGINLYVK 299
              E A+KAVDE+NG E++G+ IY GRAQK+ +R  ELK +FE++  ++  RYQG+NLYVK
Sbjct: 504  EPEGAEKAVDEINGTEVSGRIIYCGRAQKRAERQAELKERFEKIKLERINRYQGVNLYVK 325

Query: 300  NLDDGIDDERLQKEFSPFGTITSTKVMTEGGRSKGFGFVCFSSPEEATKAVSEMNGRIVA 359
            NLDD IDDERL+KEFS FGTITS K+MTEGGRSKGFGFVCFSSPEEATKAV+EMNGRI+ 
Sbjct: 324  NLDDSIDDERLRKEFSNFGTITSAKIMTEGGRSKGFGFVCFSSPEEATKAVTEMNGRIIV 145

Query: 360  TKPLYVALAQRKEERQAHLTNQYIQRMASVR 390
             KPLYVALAQRKE+R+A L ++Y+Q MA++R
Sbjct: 144  AKPLYVALAQRKEDRRAQLASRYMQHMANLR 52
>39438
          Length = 2557

 Score =  120 bits (300), Expect = 2e-27,   Method: Compositional matrix adjust.
 Identities = 65/88 (73%), Positives = 70/88 (79%), Gaps = 1/88 (1%)
 Frame = +2

Query: 529 AVCIQGQEPWTASMLVTAP-QEPKQMLGERLFPLIQAMHPTLAGKITGMLLDIDNSEPLR 587
           +V I GQEP TASML  AP QE KQMLGERLFPLIQ M+P LAGKITGMLL+IDNSE L 
Sbjct: 188 SVVIPGQEPLTASMLAAAPPQEQKQMLGERLFPLIQRMYPDLAGKITGMLLEIDNSELLH 367

Query: 588 MLESPVSRCSRAEEAVATLQAHQVKEAA 615
           MLES  S  ++ EEAVA LQAHQ KEAA
Sbjct: 368 MLESQESLKAKVEEAVAVLQAHQAKEAA 451
>25691
          Length = 768

 Score = 73.9 bits (180), Expect = 2e-13,   Method: Compositional matrix adjust.
 Identities = 40/126 (31%), Positives = 75/126 (59%), Gaps = 2/126 (1%)
 Frame = -2

Query: 39  SIRVYRDVITRRSLGYASVNFEQPADAERALDTMNFDVIKGKPVRIMWSQRDPSLRRSGV 98
           + ++ RD  T +SLGY  VN+++  DA++A+ T+N   ++ K +++  ++  PS      
Sbjct: 434 TCKLIRDKPTGQSLGYGFVNYKRQEDADKAIHTLNGLRLQNKTIKVSLAR--PSCESIKG 261

Query: 99  GNVFIKNLNKTIDNKALYDTFSAFGNILSCKVVSDENG--SKGHGFVHFETEEAAERAIE 156
            N++I  L K++    L + F+  GNI++ +++ D+    SKG GF+ F+    AERAI+
Sbjct: 260 ANLYISGLPKSLTQLDLENLFTDCGNIITSRILYDQTTGLSKGVGFIRFDQRIEAERAIQ 81

Query: 157 KMNGML 162
           K+N  +
Sbjct: 80  KLNNHI 63

 Score = 50.8 bits (120), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 39/134 (29%), Positives = 61/134 (45%), Gaps = 4/134 (2%)
 Frame = -2

Query: 239 ERHEDAQKAVDEMNGKELNGKHIYVGRAQKKDDRHTELKHKFEQVTQDKSIRYQGINLYV 298
           +R EDA KA+  +NG  L  K I V  A+   +                SI+  G NLY+
Sbjct: 371 KRQEDADKAIHTLNGLRLQNKTIKVSLARPSCE----------------SIK--GANLYI 246

Query: 299 KNLDDGIDDERLQKEFSPFGTITSTKVMTE--GGRSKGFGFVCFSSPEEATKAVSEMNGR 356
             L   +    L+  F+  G I +++++ +   G SKG GF+ F    EA +A+ ++N  
Sbjct: 245 SGLPKSLTQLDLENLFTDCGNIITSRILYDQTTGLSKGVGFIRFDQRIEAERAIQKLNNH 66

Query: 357 IV--ATKPLYVALA 368
           I      P+ V  A
Sbjct: 65  IPDGCIDPITVKFA 24

 Score = 46.2 bits (108), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 26/102 (25%), Positives = 53/102 (51%), Gaps = 2/102 (1%)
 Frame = -2

Query: 127 SCKVVSDE--NGSKGHGFVHFETEEAAERAIEKMNGMLLNDRKVFVGRFKSQKEREAELG 184
           +CK++ D+    S G+GFV+++ +E A++AI  +NG+ L ++ + V   +   E      
Sbjct: 434 TCKLIRDKPTGQSLGYGFVNYKRQEDADKAIHTLNGLRLQNKTIKVSLARPSCE------ 273

Query: 185 TGTKEFTNVYIKNFGDRMDDETLNGLFGRFGQILSVKVMTDE 226
             + +  N+YI      +    L  LF   G I++ +++ D+
Sbjct: 272 --SIKGANLYISGLPKSLTQLDLENLFTDCGNIITSRILYDQ 153

 Score = 42.0 bits (97), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 23/79 (29%), Positives = 41/79 (51%), Gaps = 2/79 (2%)
 Frame = -2

Query: 11  ASLYVGDLHPDVTEAMLYEKFSSAGPILSIRVYRDVITRRSLGYASVNFEQPADAERALD 70
           A+LY+  L   +T+  L   F+  G I++ R+  D  T  S G   + F+Q  +AERA+ 
Sbjct: 260 ANLYISGLPKSLTQLDLENLFTDCGNIITSRILYDQTTGLSKGVGFIRFDQRIEAERAIQ 81

Query: 71  TMNFDVIKG--KPVRIMWS 87
            +N  +  G   P+ + ++
Sbjct: 80  KLNNHIPDGCIDPITVKFA 24

 Score = 34.7 bits (78), Expect = 0.11,   Method: Compositional matrix adjust.
 Identities = 16/40 (40%), Positives = 26/40 (65%)
 Frame = -2

Query: 330 GRSKGFGFVCFSSPEEATKAVSEMNGRIVATKPLYVALAQ 369
           G+S G+GFV +   E+A KA+  +NG  +  K + V+LA+
Sbjct: 404 GQSLGYGFVNYKRQEDADKAIHTLNGLRLQNKTIKVSLAR 285
>17681
          Length = 964

 Score = 70.9 bits (172), Expect = 1e-12,   Method: Compositional matrix adjust.
 Identities = 60/205 (29%), Positives = 86/205 (41%), Gaps = 45/205 (21%)
 Frame = +2

Query: 13  LYVGDLHPDVTEAMLYEKFSSAGPILSIRVYRDVITRRSLGYASVNFEQPADAERALDTM 72
           ++VGDL P++    L E F+  G I + R+ RD  T +S GYA V+F + A+AE A+  M
Sbjct: 38  IFVGDLSPEIETETLREAFAPFGEISNCRIVRDPQTMKSKGYAFVSFVKKAEAENAIQAM 217

Query: 73  NFDVIKGKPVRIMWSQRD-PSLRRSG-----------------VGNVFIKNLNK------ 108
           N   I  + +R  WS R  P  R S                       IKN  +      
Sbjct: 218 NGQWIGSRSIRTNWSTRKLPPPRESSKSGGQGGGMGGMGGCGGGAGNGIKNNQRHTFEEV 397

Query: 109 -------------------TIDNKALYDTFSAFGNILSCKVVSDENGSKGHGFVHFETEE 149
                               I ++ ++  F  FG I   +V  D    KG  F+ F T+E
Sbjct: 398 YNQSSPTNTTVYCGGFPPNVISDELMHKHFMQFGPIQDVRVFKD----KGFAFIKFVTKE 565

Query: 150 AAERAIE--KMNGMLLNDRKVFVGR 172
           AA RAIE   ++ +  N  K F G+
Sbjct: 566 AAARAIEHTHISEVHGNHVKCFWGK 640

 Score = 53.1 bits (126), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 25/71 (35%), Positives = 42/71 (59%), Gaps = 2/71 (2%)
 Frame = +2

Query: 100 NVFIKNLNKTIDNKALYDTFSAFGNILSCKVVSDEN--GSKGHGFVHFETEEAAERAIEK 157
           ++F+ +L+  I+ + L + F+ FG I +C++V D     SKG+ FV F  +  AE AI+ 
Sbjct: 35  HIFVGDLSPEIETETLREAFAPFGEISNCRIVRDPQTMKSKGYAFVSFVKKAEAENAIQA 214

Query: 158 MNGMLLNDRKV 168
           MNG  +  R +
Sbjct: 215 MNGQWIGSRSI 247

 Score = 51.6 bits (122), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 24/79 (30%), Positives = 47/79 (59%), Gaps = 2/79 (2%)
 Frame = +2

Query: 295 NLYVKNLDDGIDDERLQKEFSPFGTITSTKVMTE--GGRSKGFGFVCFSSPEEATKAVSE 352
           +++V +L   I+ E L++ F+PFG I++ +++ +    +SKG+ FV F    EA  A+  
Sbjct: 35  HIFVGDLSPEIETETLREAFAPFGEISNCRIVRDPQTMKSKGYAFVSFVKKAEAENAIQA 214

Query: 353 MNGRIVATKPLYVALAQRK 371
           MNG+ + ++ +    + RK
Sbjct: 215 MNGQWIGSRSIRTNWSTRK 271

 Score = 42.7 bits (99), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 42/202 (20%), Positives = 78/202 (38%), Gaps = 35/202 (17%)
 Frame = +2

Query: 192 NVYIKNFGDRMDDETLNGLFGRFGQILSVKVMTD-EXXXXXXXXXXXXERHEDAQKAVDE 250
           ++++ +    ++ ETL   F  FG+I + +++ D +             +  +A+ A+  
Sbjct: 35  HIFVGDLSPEIETETLREAFAPFGEISNCRIVRDPQTMKSKGYAFVSFVKKAEAENAIQA 214

Query: 251 MNGKELNGKHIYVGRAQKK----------------------------DDRHTELKHKFEQ 282
           MNG+ +  + I    + +K                            +      +H FE+
Sbjct: 215 MNGQWIGSRSIRTNWSTRKLPPPRESSKSGGQGGGMGGMGGCGGGAGNGIKNNQRHTFEE 394

Query: 283 VTQDKSIRYQGINLYVKNL-DDGIDDERLQKEFSPFGTITSTKVMTEGGRSKGFGFVCFS 341
           V    S       +Y      + I DE + K F  FG I   +V     + KGF F+ F 
Sbjct: 395 VYNQSSP--TNTTVYCGGFPPNVISDELMHKHFMQFGPIQDVRVF----KDKGFAFIKFV 556

Query: 342 SPEEATKA-----VSEMNGRIV 358
           + E A +A     +SE++G  V
Sbjct: 557 TKEAAARAIEHTHISEVHGNHV 622
>02343
          Length = 1715

 Score = 67.0 bits (162), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 45/196 (22%), Positives = 89/196 (45%), Gaps = 4/196 (2%)
 Frame = -2

Query: 100  NVFIKNLNKTIDNKALYDTFSAFGNILSCKVVSDE--NGSKGHGFVHFETEEAAERAIEK 157
            N++I+ L+    +K L +    FG I S K + D+  N  KG+GFV F+   AAERA++ 
Sbjct: 1261 NLYIRGLSPNTTDKDLVNLCQHFGTITSTKAIIDQTTNKCKGYGFVDFDAPGAAERAVQA 1082

Query: 158  MNGMLLNDRKVFVGRFKSQKEREAELGTGTKEFTNVYIKNFGDRMDDETLNGLFGRFGQI 217
            +    +        +   Q+E++          TN+YI N      ++ L GLF  +G +
Sbjct: 1081 LQAQGIQ------AQMAKQQEQDP---------TNLYIANLPLHFTEKHLEGLFKDYGTV 947

Query: 218  LSVKVMTDEXXXXXXXXXXXXERHEDAQKAVDEMNGKELNG--KHIYVGRAQKKDDRHTE 275
            +S +++               E  +     ++  N K ++G  + + V  A   + + ++
Sbjct: 946  ISTRILRKPDGISRCVGFARMESRDKCDTVINTFNNKMISGCSEPLLVKFADSGNKKKSQ 767

Query: 276  LKHKFEQVTQDKSIRY 291
             + K  Q+ +D  +++
Sbjct: 766  -QQKMFQLGRDDGLQF 722

 Score = 61.6 bits (148), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 46/182 (25%), Positives = 83/182 (45%), Gaps = 9/182 (4%)
 Frame = -2

Query: 12   SLYVGDLHPDVTEAMLYEKFSSAGPILSIRVYRDVITRRSLGYASVNFEQPADAERALDT 71
            +LY+  L P+ T+  L       G I S +   D  T +  GY  V+F+ P  AERA+  
Sbjct: 1261 NLYIRGLSPNTTDKDLVNLCQHFGTITSTKAIIDQTTNKCKGYGFVDFDAPGAAERAVQA 1082

Query: 72   MNFDVIKGKPVRIMWSQRDPSLRRSGVGNVFIKNLNKTIDNKALYDTFSAFGNILSCKVV 131
            +    I+ +  +    ++DP+       N++I NL      K L   F  +G ++S +++
Sbjct: 1081 LQAQGIQAQMAK--QQEQDPT-------NLYIANLPLHFTEKHLEGLFKDYGTVISTRIL 929

Query: 132  SDENG-SKGHGFVHFETEEAAERAIEKMNG-MLLNDRKVFVGRF-------KSQKEREAE 182
               +G S+  GF   E+ +  +  I   N  M+    +  + +F       KSQ+++  +
Sbjct: 928  RKPDGISRCVGFARMESRDKCDTVINTFNNKMISGCSEPLLVKFADSGNKKKSQQQKMFQ 749

Query: 183  LG 184
            LG
Sbjct: 748  LG 743

 Score = 48.5 bits (114), Expect = 8e-06,   Method: Compositional matrix adjust.
 Identities = 30/94 (31%), Positives = 47/94 (50%), Gaps = 2/94 (2%)
 Frame = -2

Query: 295  NLYVKNLDDGIDDERLQKEFSPFGTITSTKVMTE--GGRSKGFGFVCFSSPEEATKAVSE 352
            NLY++ L     D+ L      FGTITSTK + +    + KG+GFV F +P  A +AV  
Sbjct: 1261 NLYIRGLSPNTTDKDLVNLCQHFGTITSTKAIIDQTTNKCKGYGFVDFDAPGAAERAVQA 1082

Query: 353  MNGRIVATKPLYVALAQRKEERQAHLTNQYIQRM 386
            +  + +         AQ  ++++   TN YI  +
Sbjct: 1081 LQAQGIQ--------AQMAKQQEQDPTNLYIANL 1004

 Score = 47.0 bits (110), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 39/191 (20%), Positives = 80/191 (41%), Gaps = 4/191 (2%)
 Frame = -2

Query: 191  TNVYIKNFGDRMDDETLNGLFGRFGQILSVKVMTDEXXXXXXXX-XXXXERHEDAQKAVD 249
            TN+YI+       D+ L  L   FG I S K + D+             +    A++AV 
Sbjct: 1264 TNLYIRGLSPNTTDKDLVNLCQHFGTITSTKAIIDQTTNKCKGYGFVDFDAPGAAERAVQ 1085

Query: 250  EMNGKELNGKHIYVGRAQKKDDRHTELKHKFEQVTQDKSIRYQGINLYVKNLDDGIDDER 309
             +  + +  +   + + Q++D                        NLY+ NL     ++ 
Sbjct: 1084 ALQAQGIQAQ---MAKQQEQDP----------------------TNLYIANLPLHFTEKH 980

Query: 310  LQKEFSPFGTITSTKVMTE-GGRSKGFGFVCFSSPEEATKAVSEMNGRIVA--TKPLYVA 366
            L+  F  +GT+ ST+++ +  G S+  GF    S ++    ++  N ++++  ++PL V 
Sbjct: 979  LEGLFKDYGTVISTRILRKPDGISRCVGFARMESRDKCDTVINTFNNKMISGCSEPLLVK 800

Query: 367  LAQRKEERQAH 377
             A    ++++ 
Sbjct: 799  FADSGNKKKSQ 767
>08958
          Length = 680

 Score = 62.0 bits (149), Expect = 8e-10,   Method: Compositional matrix adjust.
 Identities = 45/154 (29%), Positives = 80/154 (51%), Gaps = 3/154 (1%)
 Frame = +2

Query: 13  LYVGDLHPDVTEAMLYEKFSSAGPILSIRVYRDVITRRSLGYASVNFEQPADAERA-LDT 71
           L+VG+L PDV+E    + FS  G +    V     + R  G+  +++   A+A +A LD 
Sbjct: 74  LFVGNLTPDVSEDDFKKLFSPFGEVSEAYVN----SGRGFGFIRLDYRHNAEAAKAALDG 241

Query: 72  MNFDVIKGKPVRIMWSQRDPSLRRSGVGNVFIKNLNKTIDNKALYDTFSAFGNILSCKVV 131
           +     KG+ +R+ ++    +L+        +KNL+  + N+ L   F+ FG++    V+
Sbjct: 242 LQ---RKGRSLRVRYATHGAALK--------VKNLHPYVSNELLEQAFTQFGDLERAIVI 388

Query: 132 SDENG-SKGHGFVHFETEEAAERAIEKMN-GMLL 163
            DE G S G G V F  +  A++A+ ++N G+ L
Sbjct: 389 VDERGRSTGEGVVEFVRKPGAQQALRRINEGVFL 490

 Score = 40.8 bits (94), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 43/173 (24%), Positives = 65/173 (37%), Gaps = 3/173 (1%)
 Frame = +2

Query: 83  RIMWSQRDPSLRR---SGVGNVFIKNLNKTIDNKALYDTFSAFGNILSCKVVSDENGSKG 139
           R   S+R    RR   +G   +F+ NL   +        FS FG +    V    N  +G
Sbjct: 11  RTSASRRVKEYRRKKFTGRCRLFVGNLTPDVSEDDFKKLFSPFGEVSEAYV----NSGRG 178

Query: 140 HGFVHFETEEAAERAIEKMNGMLLNDRKVFVGRFKSQKEREAELGTGTKEFTNVYIKNFG 199
            GF+  +    AE A   ++G+    R + V        R A  G   K      +KN  
Sbjct: 179 FGFIRLDYRHNAEAAKAALDGLQRKGRSLRV--------RYATHGAALK------VKNLH 316

Query: 200 DRMDDETLNGLFGRFGQILSVKVMTDEXXXXXXXXXXXXERHEDAQKAVDEMN 252
             + +E L   F +FG +    V+ DE             R   AQ+A+  +N
Sbjct: 317 PYVSNELLEQAFTQFGDLERAIVIVDERGRSTGEGVVEFVRKPGAQQALRRIN 475
>11687
          Length = 676

 Score = 60.8 bits (146), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 45/156 (28%), Positives = 78/156 (50%), Gaps = 9/156 (5%)
 Frame = +3

Query: 13  LYVGDLHPDVTEAMLYEKFSSAGPILSIRVYRDVITRRSLGYASVNF---EQPADAERAL 69
           ++VG +  ++ E  L + F   GP+ S+ + RD  T +S G   V F   +   DA+ AL
Sbjct: 156 MFVGQIPRNMDENELRKMFEDYGPVHSLNILRDKNTGQSKGCCFVTFFTRKAALDAQNAL 335

Query: 70  DTMNFDVIKGKPVRIMWSQRDPSLRRSGVGNV-----FIKNLNKTIDNKALYDTFSAFGN 124
             +    +   PV++  +    S +R+G  NV     F+  L+K +    +   F +FG+
Sbjct: 336 HNVKTMPMMHHPVQMKPAD---SEKRNGERNVEERKLFVGMLSKKLSENDVRMLFESFGS 506

Query: 125 ILSCKVVSDENG-SKGHGFVHFETEEAAERAIEKMN 159
           I  C V+ D NG S+G  F+ F + + A  +I+ M+
Sbjct: 507 IDDCTVLRDSNGTSRGCAFITFASRQCAMNSIKGMH 614
>03744
          Length = 3486

 Score = 58.9 bits (141), Expect = 6e-09,   Method: Compositional matrix adjust.
 Identities = 31/84 (36%), Positives = 45/84 (53%), Gaps = 2/84 (2%)
 Frame = -1

Query: 293  GINLYVKNLDDGIDDERLQKEFSPFGTITSTKVMTEG--GRSKGFGFVCFSSPEEATKAV 350
            G NL++ +L     D+ L + F PFG + S KV  +     SK FGFV + SP  A  A+
Sbjct: 3219 GANLFIYHLPQEFGDQDLMQMFMPFGNVVSAKVFIDKQTNLSKCFGFVSYDSPLAAQAAI 3040

Query: 351  SEMNGRIVATKPLYVALAQRKEER 374
            + MNG  +  K L V L + K ++
Sbjct: 3039 TSMNGFQIGMKRLKVQLKRSKNDK 2968

 Score = 49.3 bits (116), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 28/82 (34%), Positives = 48/82 (58%), Gaps = 2/82 (2%)
 Frame = -1

Query: 100  NVFIKNLNKTIDNKALYDTFSAFGNILSCKVVSDE--NGSKGHGFVHFETEEAAERAIEK 157
            N+FI +L +   ++ L   F  FGN++S KV  D+  N SK  GFV +++  AA+ AI  
Sbjct: 3213 NLFIYHLPQEFGDQDLMQMFMPFGNVVSAKVFIDKQTNLSKCFGFVSYDSPLAAQAAITS 3034

Query: 158  MNGMLLNDRKVFVGRFKSQKER 179
            MNG  +  +++ V   +S+ ++
Sbjct: 3033 MNGFQIGMKRLKVQLKRSKNDK 2968
>20488
          Length = 3281

 Score = 58.5 bits (140), Expect = 7e-09,   Method: Compositional matrix adjust.
 Identities = 31/84 (36%), Positives = 45/84 (53%), Gaps = 2/84 (2%)
 Frame = +2

Query: 293  GINLYVKNLDDGIDDERLQKEFSPFGTITSTKVMTE--GGRSKGFGFVCFSSPEEATKAV 350
            G NL++ +L     D+ L + F PFG + S KV  +     SK FGFV + SP  A  A+
Sbjct: 2705 GANLFIYHLPQEFGDQDLMQMFMPFGNVVSAKVFIDKQTNLSKCFGFVSYDSPLAAQAAI 2884

Query: 351  SEMNGRIVATKPLYVALAQRKEER 374
            + MNG  +  K L V L + K ++
Sbjct: 2885 TSMNGFQIGMKRLKVQLKRSKNDK 2956

 Score = 48.5 bits (114), Expect = 8e-06,   Method: Compositional matrix adjust.
 Identities = 28/82 (34%), Positives = 48/82 (58%), Gaps = 2/82 (2%)
 Frame = +2

Query: 100  NVFIKNLNKTIDNKALYDTFSAFGNILSCKVVSDE--NGSKGHGFVHFETEEAAERAIEK 157
            N+FI +L +   ++ L   F  FGN++S KV  D+  N SK  GFV +++  AA+ AI  
Sbjct: 2711 NLFIYHLPQEFGDQDLMQMFMPFGNVVSAKVFIDKQTNLSKCFGFVSYDSPLAAQAAITS 2890

Query: 158  MNGMLLNDRKVFVGRFKSQKER 179
            MNG  +  +++ V   +S+ ++
Sbjct: 2891 MNGFQIGMKRLKVQLKRSKNDK 2956
>16427
          Length = 1313

 Score = 58.5 bits (140), Expect = 7e-09,   Method: Compositional matrix adjust.
 Identities = 32/77 (41%), Positives = 50/77 (64%), Gaps = 2/77 (2%)
 Frame = +1

Query: 296 LYVKNLDDGIDDERLQKEFSPFGTITSTKVMTEGGR--SKGFGFVCFSSPEEATKAVSEM 353
           L+V  L + ID++ L++EFS FG IT + V+ +  R  S+GFGFV + +P +A +AV  M
Sbjct: 142 LFVGGLAEEIDEKVLEREFSKFGRITESMVIRDKVRQVSRGFGFVTYENPMDAEEAVKHM 321

Query: 354 NGRIVATKPLYVALAQR 370
           +G+ +  K L+V  A R
Sbjct: 322 DGKEILGKKLHVEDAVR 372
>14258
          Length = 1063

 Score = 54.7 bits (130), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 29/73 (39%), Positives = 40/73 (54%), Gaps = 2/73 (2%)
 Frame = +2

Query: 304 GIDDERLQKEFSPFGTITSTKVMTEG--GRSKGFGFVCFSSPEEATKAVSEMNGRIVATK 361
           G+ D+ L + F PFG + S KV  +     SK FGFV + SP  A  A+S MNG  +  K
Sbjct: 92  GVGDQDLMQMFMPFGNVISAKVFIDKQTNLSKCFGFVSYDSPMSAQDAISSMNGFQIGMK 271

Query: 362 PLYVALAQRKEER 374
            L V L + K ++
Sbjct: 272 RLKVQLKRPKNDK 310

 Score = 42.4 bits (98), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 27/93 (29%), Positives = 49/93 (52%), Gaps = 8/93 (8%)
 Frame = +2

Query: 110 IDNKALYDTFSAFGNILSCKVVSDE--NGSKGHGFVHFETEEAAERAIEKMNGMLLNDRK 167
           + ++ L   F  FGN++S KV  D+  N SK  GFV +++  +A+ AI  MNG  +  ++
Sbjct: 95  VGDQDLMQMFMPFGNVISAKVFIDKQTNLSKCFGFVSYDSPMSAQDAISSMNGFQIGMKR 274

Query: 168 VFVGRFKSQKERE------AELGTGTKEFTNVY 194
           + V   + + ++       A LG+ + + T  Y
Sbjct: 275 LKVQLKRPKNDKPY*TSCLAXLGSASSDDTMAY 373
>30672
          Length = 877

 Score = 53.5 bits (127), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 28/82 (34%), Positives = 47/82 (57%), Gaps = 1/82 (1%)
 Frame = +3

Query: 296 LYVKNLDDGIDDERLQKEFSPFGTITSTKV-MTEGGRSKGFGFVCFSSPEEATKAVSEMN 354
           L ++NL     +  ++  F  FGTI+   + + +G RS+GF FV F+  + A KA+S+MN
Sbjct: 411 LIIRNLAFKCKEADIRSHFGKFGTISEVTIPLKQGDRSRGFAFVQFTEVKAAQKAISDMN 590

Query: 355 GRIVATKPLYVALAQRKEERQA 376
           G  +  +P+ V  A  K+  +A
Sbjct: 591 GTAIMDRPVAVDWAVAKDRFEA 656

 Score = 38.9 bits (89), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 25/73 (34%), Positives = 41/73 (56%), Gaps = 5/73 (6%)
 Frame = +3

Query: 292 QGINLYVKNLDDGIDDERLQKEFSPFGTITSTKVMT--EGGRSKGFGFVCFSSPEEATKA 349
           Q   L+V+NL     +E+L + F   G + +  V+   E G+ +GFG+V FS  E+A KA
Sbjct: 6   QSKTLFVRNLPFETSNEKLLEAFEQVGPLKTAFVVAGKEPGKCRGFGYVQFSMLEDAIKA 185

Query: 350 ---VSEMNGRIVA 359
              V+  +GR ++
Sbjct: 186 KDTVTHCSGRKIS 224

 Score = 36.6 bits (83), Expect = 0.028,   Method: Compositional matrix adjust.
 Identities = 48/224 (21%), Positives = 82/224 (36%), Gaps = 39/224 (17%)
 Frame = +3

Query: 101 VFIKNLNKTIDNKALYDTFSAFGNILSCKVVSDENGSK--GHGFVHFETEEAAERAIE-- 156
           +F++NL     N+ L + F   G + +  VV+ +   K  G G+V F   E A +A +  
Sbjct: 18  LFVRNLPFETSNEKLLEAFEQVGPLKTAFVVAGKEPGKCRGFGYVQFSMLEDAIKAKDTV 197

Query: 157 ------KMNGMLLNDRKVFVGRFKSQKEREAELGTGTK---------------------- 188
                 K++    + +K +  + K   E    LG G K                      
Sbjct: 198 THCSGRKISLSFADTKKSWKTKQKGGTETSDALGLGKKLPSQTAVTDGEPNPKPEKKKTK 377

Query: 189 -------EFTNVYIKNFGDRMDDETLNGLFGRFGQILSVKVMTDEXXXXXXXXXXXXERH 241
                  +   + I+N   +  +  +   FG+FG I  V +   +               
Sbjct: 378 QPKQELGKRCRLIIRNLAFKCKEADIRSHFGKFGTISEVTIPLKQGDRSRGFAFVQFTEV 557

Query: 242 EDAQKAVDEMNGKELNGKHIYVGRAQKKDDRHTELKHKFEQVTQ 285
           + AQKA+ +MNG  +  + + V  A  KD        +FE  TQ
Sbjct: 558 KAAQKAISDMNGTAIMDRPVAVDWAVAKD--------RFEASTQ 665

 Score = 32.3 bits (72), Expect = 0.54,   Method: Compositional matrix adjust.
 Identities = 21/75 (28%), Positives = 34/75 (45%)
 Frame = +3

Query: 13  LYVGDLHPDVTEAMLYEKFSSAGPILSIRVYRDVITRRSLGYASVNFEQPADAERALDTM 72
           L + +L     EA +   F   G I  + +       RS G+A V F +   A++A+  M
Sbjct: 411 LIIRNLAFKCKEADIRSHFGKFGTISEVTIPLKQ-GDRSRGFAFVQFTEVKAAQKAISDM 587

Query: 73  NFDVIKGKPVRIMWS 87
           N   I  +PV + W+
Sbjct: 588 NGTAIMDRPVAVDWA 632
>13822
          Length = 963

 Score = 52.8 bits (125), Expect = 4e-07,   Method: Compositional matrix adjust.
 Identities = 25/56 (44%), Positives = 33/56 (58%)
 Frame = -1

Query: 115 LYDTFSAFGNILSCKVVSDENGSKGHGFVHFETEEAAERAIEKMNGMLLNDRKVFV 170
           L      FG IL  +++ +E GSKG GFV F     AERA +KMNG ++  RK+ V
Sbjct: 294 LRQLLGPFGTILDVEIIFNERGSKGFGFVTFAHSAEAERARDKMNGTVVEGRKIEV 127

 Score = 48.1 bits (113), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 25/70 (35%), Positives = 39/70 (55%)
 Frame = -1

Query: 296 LYVKNLDDGIDDERLQKEFSPFGTITSTKVMTEGGRSKGFGFVCFSSPEEATKAVSEMNG 355
           L+V N+     +  L++   PFGTI   +++     SKGFGFV F+   EA +A  +MNG
Sbjct: 336 LHVSNIPFRFREADLRQLLGPFGTILDVEIIFNERGSKGFGFVTFAHSAEAERARDKMNG 157

Query: 356 RIVATKPLYV 365
            +V  + + V
Sbjct: 156 TVVEGRKIEV 127
>02140
          Length = 1796

 Score = 51.6 bits (122), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 32/86 (37%), Positives = 44/86 (51%)
 Frame = +3

Query: 3   SSDPGCPMASLYVGDLHPDVTEAMLYEKFSSAGPILSIRVYRDVITRRSLGYASVNFEQP 62
            +D   P   L+V  L+P  T+  L   FS  GPI S  V RD  T+ SL YA V FE+P
Sbjct: 777 DADTKPPDNVLFVCKLNPVTTDEDLEMIFSRFGPITSCEVIRDHKTKESLQYAFVEFEKP 956

Query: 63  ADAERALDTMNFDVIKGKPVRIMWSQ 88
              E A   M+  +I  + + + +SQ
Sbjct: 957 EHCENAYFKMDNVLIDDRRIHVDFSQ 1034
>14637
          Length = 455

 Score = 50.8 bits (120), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 27/65 (41%), Positives = 36/65 (55%), Gaps = 2/65 (3%)
 Frame = -1

Query: 293 GINLYVKNLDDGIDDERLQKEFSPFGTITSTKVMTE--GGRSKGFGFVCFSSPEEATKAV 350
           G NL++ +L     D+ L + F PFG + S KV  +     SK FGFV + SP  A  A+
Sbjct: 206 GSNLFIYHLPQEFGDQDLMQMFMPFGNVISAKVFIDKQTNLSKCFGFVSYDSPMSAQDAI 27

Query: 351 SEMNG 355
           S MNG
Sbjct: 26  SSMNG 12

 Score = 45.8 bits (107), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 26/66 (39%), Positives = 39/66 (59%), Gaps = 2/66 (3%)
 Frame = -1

Query: 100 NVFIKNLNKTIDNKALYDTFSAFGNILSCKVVSDE--NGSKGHGFVHFETEEAAERAIEK 157
           N+FI +L +   ++ L   F  FGN++S KV  D+  N SK  GFV +++  +A+ AI  
Sbjct: 200 NLFIYHLPQEFGDQDLMQMFMPFGNVISAKVFIDKQTNLSKCFGFVSYDSPMSAQDAISS 21

Query: 158 MNGMLL 163
           MNG  L
Sbjct: 20  MNGFRL 3
>28455
          Length = 573

 Score = 48.9 bits (115), Expect = 6e-06,   Method: Compositional matrix adjust.
 Identities = 26/72 (36%), Positives = 41/72 (56%), Gaps = 1/72 (1%)
 Frame = -1

Query: 101 VFIKNLNKTIDNKALYDTFSAFGNILSCKVVSDENG-SKGHGFVHFETEEAAERAIEKMN 159
           +F+KNL  T   +AL   F   G +   ++V+  +G SKG  +V FETEE A +A+ K +
Sbjct: 534 LFVKNLPFTCSAEALETIFKEHGKVKDVRLVTYRSGASKGLAYVEFETEEMATQAVMKTD 355

Query: 160 GMLLNDRKVFVG 171
           G+ + D  + V 
Sbjct: 354 GLQVGDHMISVA 319
>31310
          Length = 469

 Score = 48.5 bits (114), Expect = 8e-06,   Method: Compositional matrix adjust.
 Identities = 24/74 (32%), Positives = 41/74 (55%), Gaps = 2/74 (2%)
 Frame = -3

Query: 101 VFIKNLNKTIDNKALYDTFSAFGNILSCKVVSD--ENGSKGHGFVHFETEEAAERAIEKM 158
           +++ ++N  I    +   F  FG I S  +  D   N  KG  F+ ++  EAA+ A+E+M
Sbjct: 317 IYVGSINFEIREDTIKQAFLPFGPIKSVNLSWDPITNKHKGFSFIEYDVPEAAQLALEQM 138

Query: 159 NGMLLNDRKVFVGR 172
           NG+++  R + VGR
Sbjct: 137 NGVMIGGRNIKVGR 96

 Score = 47.8 bits (112), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 22/75 (29%), Positives = 44/75 (58%)
 Frame = -3

Query: 10  MASLYVGDLHPDVTEAMLYEKFSSAGPILSIRVYRDVITRRSLGYASVNFEQPADAERAL 69
           M  +YVG ++ ++ E  + + F   GPI S+ +  D IT +  G++ + ++ P  A+ AL
Sbjct: 326 MCRIYVGSINFEIREDTIKQAFLPFGPIKSVNLSWDPITNKHKGFSFIEYDVPEAAQLAL 147

Query: 70  DTMNFDVIKGKPVRI 84
           + MN  +I G+ +++
Sbjct: 146 EQMNGVMIGGRNIKV 102

 Score = 43.5 bits (101), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 21/72 (29%), Positives = 41/72 (56%), Gaps = 2/72 (2%)
 Frame = -3

Query: 296 LYVKNLDDGIDDERLQKEFSPFGTITSTKVMTE--GGRSKGFGFVCFSSPEEATKAVSEM 353
           +YV +++  I ++ +++ F PFG I S  +  +    + KGF F+ +  PE A  A+ +M
Sbjct: 317 IYVGSINFEIREDTIKQAFLPFGPIKSVNLSWDPITNKHKGFSFIEYDVPEAAQLALEQM 138

Query: 354 NGRIVATKPLYV 365
           NG ++  + + V
Sbjct: 137 NGVMIGGRNIKV 102

 Score = 32.0 bits (71), Expect = 0.79,   Method: Compositional matrix adjust.
 Identities = 21/74 (28%), Positives = 36/74 (48%), Gaps = 1/74 (1%)
 Frame = -3

Query: 193 VYIKNFGDRMDDETLNGLFGRFGQILSVKVMTDEXXXXXX-XXXXXXERHEDAQKAVDEM 251
           +Y+ +    + ++T+   F  FG I SV +  D              +  E AQ A+++M
Sbjct: 317 IYVGSINFEIREDTIKQAFLPFGPIKSVNLSWDPITNKHKGFSFIEYDVPEAAQLALEQM 138

Query: 252 NGKELNGKHIYVGR 265
           NG  + G++I VGR
Sbjct: 137 NGVMIGGRNIKVGR 96
>28605
          Length = 697

 Score = 47.4 bits (111), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 26/69 (37%), Positives = 39/69 (56%), Gaps = 1/69 (1%)
 Frame = -3

Query: 101 VFIKNLNKTIDNKA-LYDTFSAFGNILSCKVVSDENGSKGHGFVHFETEEAAERAIEKMN 159
           VF+ NL+    ++A L + FS +GN+L   V  +      +GFV F TEE   RA+E MN
Sbjct: 563 VFVANLSSDETSEAELQELFSKYGNVLDTLVHHNR-----YGFVQFSTEEEGRRAVEAMN 399

Query: 160 GMLLNDRKV 168
           G +   +K+
Sbjct: 398 GYMFYRKKL 372

 Score = 39.3 bits (90), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 26/78 (33%), Positives = 38/78 (48%), Gaps = 1/78 (1%)
 Frame = -3

Query: 287 KSIRYQGINLYVKNLD-DGIDDERLQKEFSPFGTITSTKVMTEGGRSKGFGFVCFSSPEE 345
           K  ++    ++V NL  D   +  LQ+ FS +G +  T V         +GFV FS+ EE
Sbjct: 590 KEPKFLNSRVFVANLSSDETSEAELQELFSKYGNVLDTLV-----HHNRYGFVQFSTEEE 426

Query: 346 ATKAVSEMNGRIVATKPL 363
             +AV  MNG +   K L
Sbjct: 425 GRRAVEAMNGYMFYRKKL 372
>13457
          Length = 4857

 Score = 33.5 bits (75), Expect(2) = 2e-05,   Method: Compositional matrix adjust.
 Identities = 13/37 (35%), Positives = 20/37 (54%)
 Frame = -3

Query: 292  QGINLYVKNLDDGIDDERLQKEFSPFGTITSTKVMTE 328
            +G NL++ +L     D  L + F PFG + S KV  +
Sbjct: 2428 EGCNLFIYHLPQXXGDAELAQMFVPFGNVISAKVYVD 2318

 Score = 33.1 bits (74), Expect(2) = 2e-05,   Method: Compositional matrix adjust.
 Identities = 16/43 (37%), Positives = 23/43 (53%)
 Frame = -2

Query: 335  FGFVCFSSPEEATKAVSEMNGRIVATKPLYVALAQRKEERQAH 377
            FGFV F +P  A  A+  MNG  +  K L V L + K+  + +
Sbjct: 2294 FGFVSFDNPASAQAAIQAMNGFQIGMKRLKVQLKRPKDANRPY 2166

 Score = 45.1 bits (105), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 23/77 (29%), Positives = 38/77 (49%), Gaps = 1/77 (1%)
 Frame = -1

Query: 85   MWSQRDPSLRRSGVGNVFIKNLNKTIDNKALYDTFSAFGNILSCKVVSDENG-SKGHGFV 143
            +W +  P +       +F+  LNK    + +   F  +G I  C ++ D+NG SKG  FV
Sbjct: 3450 VWCRLTPKMTIGEDRKLFVGMLNKQQTEEDVRQLFHPYGAIEECTILRDQNGNSKGCAFV 3271

Query: 144  HFETEEAAERAIEKMNG 160
             + T   A+ AI  ++G
Sbjct: 3270 KYSTHSEAQAAINALHG 3220

 Score = 30.0 bits (66), Expect(2) = 0.013,   Method: Compositional matrix adjust.
 Identities = 13/34 (38%), Positives = 19/34 (55%)
 Frame = -3

Query: 100  NVFIKNLNKTIDNKALYDTFSAFGNILSCKVVSD 133
            N+FI +L +   +  L   F  FGN++S KV  D
Sbjct: 2419 NLFIYHLPQXXGDAELAQMFVPFGNVISAKVYVD 2318

 Score = 26.6 bits (57), Expect(2) = 0.013,   Method: Compositional matrix adjust.
 Identities = 10/29 (34%), Positives = 18/29 (62%)
 Frame = -2

Query: 140  HGFVHFETEEAAERAIEKMNGMLLNDRKV 168
             GFV F+   +A+ AI+ MNG  +  +++
Sbjct: 2294 FGFVSFDNPASAQAAIQAMNGFQIGMKRL 2208
>03200
          Length = 657

 Score = 46.2 bits (108), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 25/80 (31%), Positives = 44/80 (55%)
 Frame = -1

Query: 292 QGINLYVKNLDDGIDDERLQKEFSPFGTITSTKVMTEGGRSKGFGFVCFSSPEEATKAVS 351
           +G  +YV  +  G+ ++ L+  FS FG I +  +     R +  GFV F   E A +A++
Sbjct: 492 KGHTVYVHGI--GVTEDILKSAFSNFGNIVNINI----ERERNNGFVTFEKMESADQAIA 331

Query: 352 EMNGRIVATKPLYVALAQRK 371
            MNG +++   L V +A+R+
Sbjct: 330 NMNGSMISNVQLKVMMARRQ 271

 Score = 41.2 bits (95), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 26/74 (35%), Positives = 42/74 (56%), Gaps = 2/74 (2%)
 Frame = -1

Query: 101 VFIKNLNKTIDNKALYDTFSAFGNILSCKVVSDENGSKGHGFVHFETEEAAERAIEKMNG 160
           V++  +  T D   L   FS FGNI++  +  + N    +GFV FE  E+A++AI  MNG
Sbjct: 480 VYVHGIGVTED--ILKSAFSNFGNIVNINIERERN----NGFVTFEKMESADQAIANMNG 319

Query: 161 MLLND--RKVFVGR 172
            ++++   KV + R
Sbjct: 318 SMISNVQLKVMMAR 277
>19868
          Length = 434

 Score = 45.1 bits (105), Expect = 9e-05,   Method: Compositional matrix adjust.
 Identities = 33/135 (24%), Positives = 62/135 (45%), Gaps = 4/135 (2%)
 Frame = +2

Query: 13  LYVGDLHPDVTEAMLYEKFSSAGPILSIRVYRDVITRRSLGYASVNFEQPADAERALDTM 72
           ++VG L    +   L + F+  G I  + V +D  TRRS G+  + F  PA  ++ L   
Sbjct: 5   MFVGGLSWQTSPESLRDYFNKFGEITEVMVMKDPTTRRSRGFGFITFGDPASVDKVLAQA 184

Query: 73  NFDVIKGKPV--RIMWSQRDPSLRRSGVGNVFIKNLNKTIDNKALYDTFSAFGNILSCKV 130
             + + GK +  ++ + +R      +    +F+  L+     + + + F  FG I    +
Sbjct: 185 THE-LDGKKIDPKVAFPRRAHPRMVTRTKKIFVGGLSAPTTLEDVKNYFEQFGPIEDAML 361

Query: 131 VSDE--NGSKGHGFV 143
           + D+  N  +G GFV
Sbjct: 362 MFDKQTNRHRGFGFV 406

 Score = 40.0 bits (92), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 29/93 (31%), Positives = 42/93 (45%), Gaps = 6/93 (6%)
 Frame = +2

Query: 295 NLYVKNLDDGIDDERLQKEFSPFGTITSTKVMTE--GGRSKGFGFVCFSSPEEATK---- 348
            ++V  L      E L+  F+ FG IT   VM +    RS+GFGF+ F  P    K    
Sbjct: 2   KMFVGGLSWQTSPESLRDYFNKFGEITEVMVMKDPTTRRSRGFGFITFGDPASVDKVLAQ 181

Query: 349 AVSEMNGRIVATKPLYVALAQRKEERQAHLTNQ 381
           A  E++G+ +  K   VA  +R   R    T +
Sbjct: 182 ATHELDGKKIDPK---VAFPRRAHPRMVTRTKK 271
>01278
          Length = 1082

 Score = 44.7 bits (104), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 23/59 (38%), Positives = 35/59 (59%)
 Frame = +2

Query: 11  ASLYVGDLHPDVTEAMLYEKFSSAGPILSIRVYRDVITRRSLGYASVNFEQPADAERAL 69
           A++ V +L  D  E+ L E F   GPI  I + +D +T +S G+A +NF +  DA RA+
Sbjct: 635 ATIRVTNLSEDTRESDLQELFRPFGPISRIYLAKDKVTGQSKGFAFINFHRREDASRAI 811

 Score = 34.3 bits (77), Expect = 0.16,   Method: Compositional matrix adjust.
 Identities = 20/70 (28%), Positives = 32/70 (45%), Gaps = 2/70 (2%)
 Frame = +2

Query: 94  RRSGVGNVFIKNLNKTIDNKALYDTFSAFGNILSCKVVSDE--NGSKGHGFVHFETEEAA 151
           R+     + + NL++      L + F  FG I    +  D+    SKG  F++F   E A
Sbjct: 620 RKDEAATIRVTNLSEDTRESDLQELFRPFGPISRIYLAKDKVTGQSKGFAFINFHRREDA 799

Query: 152 ERAIEKMNGM 161
            RAI  ++G 
Sbjct: 800 SRAIAGVSGF 829
>28652
          Length = 918

 Score = 44.3 bits (103), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 40/171 (23%), Positives = 84/171 (49%), Gaps = 9/171 (5%)
 Frame = -2

Query: 9   PMASLYVGDLHPDVTEAMLYEKFSS-AGPILSIRVY--RDVITRRSLGYASVNFE---QP 62
           P   L+VG++    T+  + ++F   +  ++ + VY   D    ++ G+A + ++     
Sbjct: 494 PNLRLFVGNIPKSKTKEEILKEFEKHSEGLMDVIVYGSADNPKLKNRGFAFLEYDTHKNA 315

Query: 63  ADAERALDTMNFDVIKGKPVRIMWS--QRDPSLRR-SGVGNVFIKNLNKTIDNKALYDTF 119
           + A+R   T  F V +   V + W+  Q +P+    S V  ++++NL   +    L + F
Sbjct: 314 SAAKRRFTTGRFRVWQCD-VIVDWADLQEEPNEETMSKVKVLYVRNLTGDVTEDDLKEKF 138

Query: 120 SAFGNILSCKVVSDENGSKGHGFVHFETEEAAERAIEKMNGMLLNDRKVFV 170
            A+G +   K + D      +GFVH+E  E A +A++ ++G  + + ++ V
Sbjct: 137 GAYGKVERVKKIKD------YGFVHYEDREDALKALDDLHGEKIGNLEIDV 3
>03903
          Length = 983

 Score = 42.7 bits (99), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 27/82 (32%), Positives = 40/82 (48%), Gaps = 8/82 (9%)
 Frame = -1

Query: 296 LYVKNLDDGIDDERLQKEFSPF--------GTITSTKVMTEGGRSKGFGFVCFSSPEEAT 347
           LY+KNL   + +E L   F  +         +I   ++M EG R KG  FV   + E+A 
Sbjct: 452 LYIKNLSKQVTEEDLHWVFGRYVNWDKEEEKSIFDIRLMKEG-RMKGQAFVTLGTEEQAR 276

Query: 348 KAVSEMNGRIVATKPLYVALAQ 369
           KAV + N  +   KP+ V  A+
Sbjct: 275 KAVKDTNAFVFKGKPIAVHFAR 210

 Score = 30.8 bits (68), Expect = 1.7,   Method: Compositional matrix adjust.
 Identities = 22/79 (27%), Positives = 35/79 (44%), Gaps = 8/79 (10%)
 Frame = -1

Query: 193 VYIKNFGDRMDDETLNGLFGRF--------GQILSVKVMTDEXXXXXXXXXXXXERHEDA 244
           +YIKN   ++ +E L+ +FGR+          I  +++M +             E  E A
Sbjct: 452 LYIKNLSKQVTEEDLHWVFGRYVNWDKEEEKSIFDIRLMKEGRMKGQAFVTLGTE--EQA 279

Query: 245 QKAVDEMNGKELNGKHIYV 263
           +KAV + N     GK I V
Sbjct: 278 RKAVKDTNAFVFKGKPIAV 222
>15371
          Length = 383

 Score = 42.0 bits (97), Expect = 8e-04,   Method: Compositional matrix adjust.
 Identities = 21/53 (39%), Positives = 29/53 (54%), Gaps = 2/53 (3%)
 Frame = -2

Query: 293 GINLYVKNLDDGIDDERLQKEFSPFGTITSTKVMTE--GGRSKGFGFVCFSSP 343
           G NL++ +L     D+ L + F PFG + S KV  +     SK FGFV + SP
Sbjct: 160 GANLFIYHLPQEFGDQDLMQMFMPFGNVVSAKVFIDKQTNLSKCFGFVSYDSP 2

 Score = 35.0 bits (79), Expect = 0.10,   Method: Compositional matrix adjust.
 Identities = 19/50 (38%), Positives = 30/50 (60%), Gaps = 2/50 (4%)
 Frame = -2

Query: 100 NVFIKNLNKTIDNKALYDTFSAFGNILSCKVVSDE--NGSKGHGFVHFET 147
           N+FI +L +   ++ L   F  FGN++S KV  D+  N SK  GFV +++
Sbjct: 154 NLFIYHLPQEFGDQDLMQMFMPFGNVVSAKVFIDKQTNLSKCFGFVSYDS 5
>20169
          Length = 1364

 Score = 41.6 bits (96), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 24/75 (32%), Positives = 39/75 (52%)
 Frame = -1

Query: 13   LYVGDLHPDVTEAMLYEKFSSAGPILSIRVYRDVITRRSLGYASVNFEQPADAERALDTM 72
            +YVG+L     +  L +KF+  GP+ ++      + RR  G+A V FE   DAE A+  +
Sbjct: 1064 VYVGELGHGCAKQELEDKFAKYGPLKNV-----WVARRPAGFAFVEFEDNRDAEDAVQAL 900

Query: 73   NFDVIKGKPVRIMWS 87
            +   I G+  R+  S
Sbjct: 899  DGARINGRRARVEMS 855
>33516
          Length = 449

 Score = 41.2 bits (95), Expect = 0.001,   Method: Composition-based stats.
 Identities = 22/50 (44%), Positives = 28/50 (56%), Gaps = 2/50 (4%)
 Frame = +1

Query: 296 LYVKNLDDGIDDERLQKEFSPFGTITSTKVMT--EGGRSKGFGFVCFSSP 343
           ++V  L    D + LQ  FS FG IT   VM   + G+S+GFGFV F  P
Sbjct: 160 IFVGGLSWDTDQDSLQGYFSQFGEITDCIVMMNQQTGKSRGFGFVSFKDP 309
>02347
          Length = 928

 Score = 41.2 bits (95), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 24/74 (32%), Positives = 38/74 (51%)
 Frame = -3

Query: 11  ASLYVGDLHPDVTEAMLYEKFSSAGPILSIRVYRDVITRRSLGYASVNFEQPADAERALD 70
             +YVGDL PD +E  +   F+  G + ++ V      R   G+A V FE   DA+ A+ 
Sbjct: 746 GKIYVGDLPPDASEKEVERAFNYYGHLRNVWV-----ARNPPGFAFVEFEDTRDADDAVR 582

Query: 71  TMNFDVIKGKPVRI 84
            ++  V+ G  VR+
Sbjct: 581 ALDGTVVCGNRVRV 540
>00029
          Length = 2204

 Score = 41.2 bits (95), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 23/75 (30%), Positives = 37/75 (49%)
 Frame = -3

Query: 294  INLYVKNLDDGIDDERLQKEFSPFGTITSTKVMTEGGRSKGFGFVCFSSPEEATKAVSEM 353
            I +++ NL D  D E L+  F  +G++    V+      K FGFV      EA  A+S +
Sbjct: 2136 IKIFIGNLGDDTDPEELRALFEKYGSVAECDVL------KNFGFVHMVKKGEADDAISNL 1975

Query: 354  NGRIVATKPLYVALA 368
            NG  +  + + V L+
Sbjct: 1974 NGYNIGGQRMRVELS 1930

 Score = 40.4 bits (93), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 21/70 (30%), Positives = 34/70 (48%)
 Frame = -3

Query: 101  VFIKNLNKTIDNKALYDTFSAFGNILSCKVVSDENGSKGHGFVHFETEEAAERAIEKMNG 160
            +FI NL    D + L   F  +G++  C V+      K  GFVH   +  A+ AI  +NG
Sbjct: 2130 IFIGNLGDDTDPEELRALFEKYGSVAECDVL------KNFGFVHMVKKGEADDAISNLNG 1969

Query: 161  MLLNDRKVFV 170
              +  +++ V
Sbjct: 1968 YNIGGQRMRV 1939
>00302
          Length = 927

 Score = 41.2 bits (95), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 22/70 (31%), Positives = 38/70 (54%), Gaps = 2/70 (2%)
 Frame = -1

Query: 103 IKNLNKTIDNKALYDTFSAFGNILSCKVVSDENG--SKGHGFVHFETEEAAERAIEKMNG 160
           I  L+     + L + F  +G+I   +VV D     S+G  FV+F++ E A  A ++ NG
Sbjct: 453 IFGLSLYTQERGLREVFGRYGHISEVQVVYDRQTGRSRGFAFVYFKSSEDAHEAKDRCNG 274

Query: 161 MLLNDRKVFV 170
           + ++ RK+ V
Sbjct: 273 IEIDGRKIRV 244

 Score = 36.2 bits (82), Expect = 0.042,   Method: Compositional matrix adjust.
 Identities = 23/78 (29%), Positives = 41/78 (52%), Gaps = 2/78 (2%)
 Frame = -1

Query: 293 GINLYVKNLDDGIDDERLQKEFSPFGTITSTKVMTE--GGRSKGFGFVCFSSPEEATKAV 350
           G++LY +       +  L++ F  +G I+  +V+ +   GRS+GF FV F S E+A +A 
Sbjct: 447 GLSLYTQ-------ERGLREVFGRYGHISEVQVVYDRQTGRSRGFAFVYFKSSEDAHEAK 289

Query: 351 SEMNGRIVATKPLYVALA 368
              NG  +  + + V  +
Sbjct: 288 DRCNGIEIDGRKIRVDFS 235

 Score = 34.3 bits (77), Expect = 0.14,   Method: Compositional matrix adjust.
 Identities = 20/58 (34%), Positives = 30/58 (51%), Gaps = 1/58 (1%)
 Frame = -1

Query: 207 LNGLFGRFGQILSVKVMTD-EXXXXXXXXXXXXERHEDAQKAVDEMNGKELNGKHIYV 263
           L  +FGR+G I  V+V+ D +            +  EDA +A D  NG E++G+ I V
Sbjct: 417 LREVFGRYGHISEVQVVYDRQTGRSRGFAFVYFKSSEDAHEAKDRCNGIEIDGRKIRV 244
>35379
          Length = 534

 Score = 40.0 bits (92), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 23/56 (41%), Positives = 33/56 (58%), Gaps = 2/56 (3%)
 Frame = +1

Query: 118 TFSAFGNILSCKVVSDE-NGSKGHGFVHFETEEAAERAIEK-MNGMLLNDRKVFVG 171
            FSAFG +   K    E    KG+GFV FE +E A+R I+K  + ++  DRK+ +G
Sbjct: 43  VFSAFGPVKDAK**QTELECPKGYGFVTFENQEDADRIIKKEADNLIFKDRKLNIG 210

 Score = 31.6 bits (70), Expect = 0.91,   Method: Compositional matrix adjust.
 Identities = 21/61 (34%), Positives = 31/61 (50%), Gaps = 2/61 (3%)
 Frame = +1

Query: 314 FSPFGTITSTKV-MTEGGRSKGFGFVCFSSPEEATKAV-SEMNGRIVATKPLYVALAQRK 371
           FS FG +   K   TE    KG+GFV F + E+A + +  E +  I   + L +  A RK
Sbjct: 46  FSAFGPVKDAK**QTELECPKGYGFVTFENQEDADRIIKKEADNLIFKDRKLNIGPAVRK 225

Query: 372 E 372
           +
Sbjct: 226 Q 228
>02064
          Length = 1195

 Score = 39.7 bits (91), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 24/78 (30%), Positives = 42/78 (53%), Gaps = 5/78 (6%)
 Frame = +1

Query: 298 VKNLDDGIDDERLQKEFSPFGTITSTKVMTEGGRSKGFGFVCFSSPEEATKAVSEMN--- 354
           VKNL   I  + L++ F   G +  +++  + GRS G G V F++ ++A +A++ M+   
Sbjct: 91  VKNLPYAITWQDLRERFQEIGVVKYSEITMDKGRSTGQGLVRFATEDDAVRAINSMDRTR 270

Query: 355 --GRIVATKPLYVALAQR 370
             GR +  K +Y    QR
Sbjct: 271 YEGRTIGVK-MYRG*WQR 321
>31618
          Length = 716

 Score = 38.9 bits (89), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 34/107 (31%), Positives = 52/107 (48%), Gaps = 5/107 (4%)
 Frame = +1

Query: 296 LYVKNLDDGIDDERLQKEFSPFGTITSTKVMTE--GGRSKGFGFVCFSSPEEATKAVSEM 353
           L+V  L     ++ L+  F  +G I S  V T+   GRS+GF F+ F++  EA   VS  
Sbjct: 298 LFVGGLSWETTEKELRDHFGKYGEIESINVKTDPQTGRSRGFAFIVFTN-TEAIDQVSAA 474

Query: 354 NGRIVATKPLYVALAQRKEERQA---HLTNQYIQRMASVRSGPNPVN 397
              I+ +K     +  +K+ R A    L+    QR+A  +S P  VN
Sbjct: 475 EEHIINSK----KVDPKKKPRLAMARFLSVA*PQRLAMRKSKPTSVN 603

 Score = 33.9 bits (76), Expect = 0.20,   Method: Compositional matrix adjust.
 Identities = 20/47 (42%), Positives = 25/47 (53%)
 Frame = +1

Query: 13  LYVGDLHPDVTEAMLYEKFSSAGPILSIRVYRDVITRRSLGYASVNF 59
           L+VG L  + TE  L + F   G I SI V  D  T RS G+A + F
Sbjct: 298 LFVGGLSWETTEKELRDHFGKYGEIESINVKTDPQTGRSRGFAFIVF 438
>00556
          Length = 2189

 Score = 38.9 bits (89), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 44/200 (22%), Positives = 79/200 (39%), Gaps = 33/200 (16%)
 Frame = +3

Query: 6   PGCPMAS----LYVGDLHPDVTEAMLYEKF-----------SSAGPILSIRVYRDVI--- 47
           PG  M+     LYVG++   VTE  + + F           +   P++++ +  D     
Sbjct: 402 PGSAMSRQARRLYVGNIPFGVTEESMMDFFNHQMKITGLAQAEGDPVIAVHINLDKNFAF 581

Query: 48  --------TRRSLGYASVNFE-QPADAERALDTMNFDVIKGKPVRIMWSQRDPSLRRSGV 98
                   T ++L +  + +E QP    R  D      +   P     +Q  P +  + V
Sbjct: 582 LELRSVDETTQALAFDGIAYETQPLKIRRPSDYKPLPGLSENP-----TQAVPGVVSTVV 746

Query: 99  GN----VFIKNLNKTIDNKALYDTFSAFGNILSCKVVSDENG--SKGHGFVHFETEEAAE 152
            +    +F+  L   +    + +   +FG + S  +V D     SKG  F  +      +
Sbjct: 747 QDSDHKIFMGGLPSYLSEDQMKELLLSFGPLKSFNLVRDNATGLSKGFAFCEYLDPSVTD 926

Query: 153 RAIEKMNGMLLNDRKVFVGR 172
           +A   +NGM L D+K+ V R
Sbjct: 927 QACAGLNGMQLGDKKLIVQR 986

 Score = 30.8 bits (68), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 17/72 (23%), Positives = 36/72 (50%), Gaps = 2/72 (2%)
 Frame = +3

Query: 296 LYVKNLDDGIDDERLQKEFSPFGTITSTKVMTEG--GRSKGFGFVCFSSPEEATKAVSEM 353
           +++  L   + ++++++    FG + S  ++ +   G SKGF F  +  P    +A + +
Sbjct: 765 IFMGGLPSYLSEDQMKELLLSFGPLKSFNLVRDNATGLSKGFAFCEYLDPSVTDQACAGL 944

Query: 354 NGRIVATKPLYV 365
           NG  +  K L V
Sbjct: 945 NGMQLGDKKLIV 980
>12506
          Length = 1056

 Score = 38.5 bits (88), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 21/67 (31%), Positives = 34/67 (50%), Gaps = 2/67 (2%)
 Frame = -3

Query: 305  IDDERLQKEFSPFGTITSTKV--MTEGGRSKGFGFVCFSSPEEATKAVSEMNGRIVATKP 362
            +DD+ L   F PFG I   ++    E  + +GF F+ F   E+A  A+  MN   +  + 
Sbjct: 1030 VDDKVLHAAFLPFGDIVDIQIPLDYETEKHRGFAFIEFELAEDAAAAIDNMNESELFGRT 851

Query: 363  LYVALAQ 369
            + V LA+
Sbjct: 850  IRVNLAK 830

 Score = 35.4 bits (80), Expect = 0.072,   Method: Compositional matrix adjust.
 Identities = 23/68 (33%), Positives = 33/68 (48%), Gaps = 1/68 (1%)
 Frame = -3

Query: 201  RMDDETLNGLFGRFGQILSVKVMTD-EXXXXXXXXXXXXERHEDAQKAVDEMNGKELNGK 259
             +DD+ L+  F  FG I+ +++  D E            E  EDA  A+D MN  EL G+
Sbjct: 1033 EVDDKVLHAAFLPFGDIVDIQIPLDYETEKHRGFAFIEFELAEDAAAAIDNMNESELFGR 854

Query: 260  HIYVGRAQ 267
             I V  A+
Sbjct: 853  TIRVNLAK 830
>02809
          Length = 1475

 Score = 38.5 bits (88), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 21/61 (34%), Positives = 33/61 (54%)
 Frame = -1

Query: 13   LYVGDLHPDVTEAMLYEKFSSAGPILSIRVYRDVITRRSLGYASVNFEQPADAERALDTM 72
            +YVG+L     +  L +KF+  GP+ ++ V      RR  G+A V FE   DAE A+  +
Sbjct: 1328 VYVGELGHGCAKQELEDKFAKYGPLKNVWV-----ARRPAGFAFVEFEDNRDAEDAVQAL 1164

Query: 73   N 73
            +
Sbjct: 1163 D 1161
>03000
          Length = 778

 Score = 38.5 bits (88), Expect = 0.009,   Method: Compositional matrix adjust.
 Identities = 41/187 (21%), Positives = 80/187 (42%), Gaps = 7/187 (3%)
 Frame = +3

Query: 182 ELGTGTKEFTNVYIKNFGDRMDDETLNGLFGRFGQILSVKVMTDEXXXXXXXXXXXXERH 241
           +L    ++F  ++I       D+++L   F  +G+I+   VM D               +
Sbjct: 60  DLDPNAEQFRKLFIGGLSYETDEDSLRSHFETWGEIVDCIVMRDSNSKRSRGFGFIT--Y 233

Query: 242 EDAQKAVDEMNGKELNGKHIYVGRAQKKDDRHTELKHKFEQVTQDKSIRYQGIN-LYVKN 300
           +DA+ ++D+              R  K D R  + K    +    +S   Q +  ++V  
Sbjct: 234 KDAE-SIDQAQ----------ANRPHKIDGREVDTKRAMPREESGRSEVQQSVKKMFVGG 380

Query: 301 LDDGIDDERLQKEFSPFGTITSTKVMTEGG--RSKGFGFVCFSSPEEATKAV----SEMN 354
           + +   ++ ++  F+ FG IT   ++ + G  +++GF FV F   +   KAV     ++N
Sbjct: 381 VKEDTTEDMIRDTFNEFGEITGVDLIQDKGTGKNRGFCFVTFGDHDSVDKAVLKKRHDLN 560

Query: 355 GRIVATK 361
           GR V  K
Sbjct: 561 GRQVEVK 581
>32386
          Length = 674

 Score = 37.0 bits (84), Expect = 0.024,   Method: Compositional matrix adjust.
 Identities = 22/72 (30%), Positives = 37/72 (51%), Gaps = 6/72 (8%)
 Frame = +1

Query: 296 LYVKNLDDGIDDERLQKEFSPFGTITSTKVMTEGG--RSKGFGFVCFSSPEEATKAVS-- 351
           L++  L    D++ L+  F  +G I    VM +    RS+GFGF+ +   E   +A +  
Sbjct: 307 LFIGGLSYETDEDSLRSHFETWGEIVDCIVMRDSNSKRSRGFGFITYKDAESIDQAQANR 486

Query: 352 --EMNGRIVATK 361
             +++GR V TK
Sbjct: 487 PHKIDGREVDTK 522
>03059
          Length = 1154

 Score = 36.6 bits (83), Expect = 0.031,   Method: Compositional matrix adjust.
 Identities = 20/63 (31%), Positives = 35/63 (55%), Gaps = 3/63 (4%)
 Frame = -2

Query: 296 LYVKNLDDGIDDERLQKEFSPFGTITSTKVMTE---GGRSKGFGFVCFSSPEEATKAVSE 352
           ++V  L   ++ + +Q+ FS +GTI    +  +      SKG  +V + +PE+A KAV  
Sbjct: 664 VHVGRLTRNVNKDHIQEIFSLYGTIKFIDLPNDRIHPNTSKGHAYVEYENPEDAEKAVKY 485

Query: 353 MNG 355
           M+G
Sbjct: 484 MDG 476
>00781
          Length = 3170

 Score = 35.8 bits (81), Expect = 0.053,   Method: Compositional matrix adjust.
 Identities = 23/61 (37%), Positives = 30/61 (49%), Gaps = 2/61 (3%)
 Frame = -1

Query: 296  LYVKNLDDGIDDERLQKEFSPFGTIT--STKVMTEGGRSKGFGFVCFSSPEEATKAVSEM 353
            +YV+        E + + FS  GT+T  S          KG+ FV F SPEEA KAV  +
Sbjct: 2714 VYVEGFHKFTSREWISRMFSKCGTVTYVSLPCFKTTREIKGYAFVEFQSPEEAVKAVQML 2535

Query: 354  N 354
            N
Sbjct: 2534 N 2532
>32733
          Length = 709

 Score = 35.8 bits (81), Expect = 0.057,   Method: Compositional matrix adjust.
 Identities = 18/55 (32%), Positives = 31/55 (56%), Gaps = 1/55 (1%)
 Frame = +1

Query: 106 LNKTIDNKALYDTFSAFGNILSCKVVSDENG-SKGHGFVHFETEEAAERAIEKMN 159
           L+K +    +   F +FG+I  C V+ D NG S+G  F+ F + + A  +I+ M+
Sbjct: 487 LSKKLSENDVRMLFESFGSIDDCTVLRDSNGTSRGCAFITFASRQCAMNSIKGMH 651
>09736
          Length = 1319

 Score = 35.4 bits (80), Expect = 0.069,   Method: Compositional matrix adjust.
 Identities = 20/54 (37%), Positives = 28/54 (51%), Gaps = 1/54 (1%)
 Frame = -2

Query: 325  VMTEGGRSKGFGFVCFSSPEEATKAVSEMNGRI-VATKPLYVALAQRKEERQAH 377
            V+   G+SKGFGFV FS   +  +A+ EM     +  +P+ V LA  K     H
Sbjct: 1291 VLDASGKSKGFGFVRFSEENDQQRALVEMQHMTGIGRRPIKVGLAAPKRGHGFH 1130

 Score = 30.0 bits (66), Expect = 2.8,   Method: Compositional matrix adjust.
 Identities = 20/52 (38%), Positives = 29/52 (55%), Gaps = 2/52 (3%)
 Frame = -2

Query: 122  FGNILSCKVVSDENG-SKGHGFVHFETEEAAERAIEKMNGML-LNDRKVFVG 171
            + ++   KVV D +G SKG GFV F  E   +RA+ +M  M  +  R + VG
Sbjct: 1318 YRSVRGAKVVLDASGKSKGFGFVRFSEENDQQRALVEMQHMTGIGRRPIKVG 1163
>02091
          Length = 2031

 Score = 35.4 bits (80), Expect = 0.071,   Method: Compositional matrix adjust.
 Identities = 31/100 (31%), Positives = 46/100 (46%), Gaps = 5/100 (5%)
 Frame = -2

Query: 518  QHLNAQLAQQPAVCI-----QGQEPWTASMLVTAPQEPKQMLGERLFPLIQAMHPTLAGK 572
            QH + Q    P  C      QGQ    A++    PQ   QM+GE+LF L+   +P     
Sbjct: 1463 QHRHXQETAGPGDCCLSSPCQGQNE-AATVAEAHPQVQTQMIGEQLFSLMSDXYPY---- 1299

Query: 573  ITGMLLDIDNSEPLRMLESPVSRCSRAEEAVATLQAHQVK 612
             T  +L  DNSE LR++       +  + A+  L + Q+K
Sbjct: 1298 PTDXMLKFDNSELLRIMLECQQSVNYRDAAMVMLVSSQLK 1179
>08670
          Length = 1307

 Score = 35.4 bits (80), Expect = 0.074,   Method: Compositional matrix adjust.
 Identities = 27/102 (26%), Positives = 50/102 (49%), Gaps = 2/102 (1%)
 Frame = +2

Query: 5    DPGCP--MASLYVGDLHPDVTEAMLYEKFSSAGPILSIRVYRDVITRRSLGYASVNFEQP 62
            DP  P  + +L+VG++ P VTE  L + F+  GP+ S+R+  +         A +N++  
Sbjct: 929  DPKNPEGLTALWVGNVLPQVTEKRLTQMFAKHGPVASVRMLPEKYC------AFINYKLK 1090

Query: 63   ADAERALDTMNFDVIKGKPVRIMWSQRDPSLRRSGVGNVFIK 104
              A RA+  +     +G+ + I    R P    +  GN+ ++
Sbjct: 1091 ESAGRAMQYLQNQECEGQHLLI----RFPDNPINPTGNITLR 1204
>23322
          Length = 471

 Score = 35.0 bits (79), Expect = 0.085,   Method: Compositional matrix adjust.
 Identities = 20/73 (27%), Positives = 38/73 (52%), Gaps = 6/73 (8%)
 Frame = -2

Query: 296 LYVKNLDDGIDDERLQKEFSPFGTITSTKVMTEGG--RSKGFGFVCFSSPEEATKAV--- 350
           ++V  + +   ++ ++  F+ FG IT   ++ + G  +++GF FV F   +   KAV   
Sbjct: 404 MFVGGVKEDTTEDMIRDTFNEFGEITGVDLIQDKGTGKNRGFCFVTFGDHDSVDKAVLKK 225

Query: 351 -SEMNGRIVATKP 362
             ++NGR V  K 
Sbjct: 224 RHDLNGRQVEVKK 186
>25950
          Length = 417

 Score = 35.0 bits (79), Expect = 0.095,   Method: Compositional matrix adjust.
 Identities = 21/62 (33%), Positives = 31/62 (50%), Gaps = 2/62 (3%)
 Frame = -2

Query: 295 NLYVKNLDDGIDDERLQKEFSPFGTITSTKVMTE--GGRSKGFGFVCFSSPEEATKAVSE 352
           ++YV N+D G   E L+  F   GTI    ++     G  KGF ++ F S E    A++ 
Sbjct: 278 SVYVGNVDYGASAEELEAHFHGCGTINRVTILCNKADGHPKGFAYIEFGSKEYVETALA- 102

Query: 353 MN 354
           MN
Sbjct: 101 MN 96

 Score = 29.3 bits (64), Expect = 4.6,   Method: Compositional matrix adjust.
 Identities = 18/74 (24%), Positives = 33/74 (44%)
 Frame = -2

Query: 12  SLYVGDLHPDVTEAMLYEKFSSAGPILSIRVYRDVITRRSLGYASVNFEQPADAERALDT 71
           S+YVG++    +   L   F   G I  + +  +       G+A + F      E AL  
Sbjct: 278 SVYVGNVDYGASAEELEAHFHGCGTINRVTILCNKADGHPKGFAYIEFGSKEYVETAL-A 102

Query: 72  MNFDVIKGKPVRIM 85
           MN  + +G+ +++M
Sbjct: 101 MNETLFRGRQIKVM 60
>26197
          Length = 1365

 Score = 34.7 bits (78), Expect = 0.11,   Method: Compositional matrix adjust.
 Identities = 22/73 (30%), Positives = 35/73 (47%), Gaps = 6/73 (8%)
 Frame = -2

Query: 296  LYVKNLDDGIDDERLQKEFSPFGTITSTKVMTE--GGRSKGFGFVCFSSPEEATKAVS-- 351
            ++V  L      + L++ F  FG +TS  + T+   G+S+GFGFV F         V   
Sbjct: 1292 IFVGGLSWETSSKHLREYFEKFGEVTSCTLKTDLDSGKSRGFGFVVFKEAVTVDAVVKNK 1113

Query: 352  --EMNGRIVATKP 362
              ++ GR +  KP
Sbjct: 1112 EHKLQGRKIDPKP 1074
>15503
          Length = 570

 Score = 34.7 bits (78), Expect = 0.12,   Method: Composition-based stats.
 Identities = 21/77 (27%), Positives = 41/77 (53%)
 Frame = +1

Query: 101 VFIKNLNKTIDNKALYDTFSAFGNILSCKVVSDENGSKGHGFVHFETEEAAERAIEKMNG 160
           +++KNL   I  + +YD F  +G I   + V +   +KG  FV +E    A+ A + ++G
Sbjct: 154 LYVKNLPYKITAEEMYDIFGKYGAIRQIR-VGNTPETKGTAFVVYEDIFDAKNACDHLSG 330

Query: 161 MLLNDRKVFVGRFKSQK 177
             + +R + V  ++S +
Sbjct: 331 FNVCNRYLVVLYYQSTR 381

 Score = 30.8 bits (68), Expect = 1.6,   Method: Composition-based stats.
 Identities = 23/74 (31%), Positives = 32/74 (43%)
 Frame = +1

Query: 296 LYVKNLDDGIDDERLQKEFSPFGTITSTKVMTEGGRSKGFGFVCFSSPEEATKAVSEMNG 355
           LYVKNL   I  E +   F  +G I   +V      +KG  FV +    +A  A   ++G
Sbjct: 154 LYVKNLPYKITAEEMYDIFGKYGAIRQIRV-GNTPETKGTAFVVYEDIFDAKNACDHLSG 330

Query: 356 RIVATKPLYVALAQ 369
             V  + L V   Q
Sbjct: 331 FNVCNRYLVVLYYQ 372

 Score = 29.3 bits (64), Expect = 5.2,   Method: Composition-based stats.
 Identities = 21/61 (34%), Positives = 30/61 (49%)
 Frame = +1

Query: 13  LYVGDLHPDVTEAMLYEKFSSAGPILSIRVYRDVITRRSLGYASVNFEQPADAERALDTM 72
           LYV +L   +T   +Y+ F   G I  IRV     T  + G A V +E   DA+ A D +
Sbjct: 154 LYVKNLPYKITAEEMYDIFGKYGAIRQIRVGN---TPETKGTAFVVYEDIFDAKNACDHL 324

Query: 73  N 73
           +
Sbjct: 325 S 327
>03406
          Length = 1292

 Score = 34.7 bits (78), Expect = 0.13,   Method: Compositional matrix adjust.
 Identities = 24/82 (29%), Positives = 37/82 (45%), Gaps = 6/82 (7%)
 Frame = +3

Query: 296 LYVKNLDDGIDDERLQKEFSPFGTITSTKVMTE--GGRSKGFGFVCFSSPEEATKAVS-- 351
           ++V  L      + L++ F  FG +TS  + T+   G+S+GFGFV F         V   
Sbjct: 246 IFVGGLSWETXSKHLREYFEKFGEVTSCTLKTDLDSGKSRGFGFVVFKEAATVDAVVKNK 425

Query: 352 --EMNGRIVATKPLYVALAQRK 371
             ++ GR +  KP       RK
Sbjct: 426 EHKLQGRKIDPKPANPRKGMRK 491
>39789
          Length = 361

 Score = 34.7 bits (78), Expect = 0.13,   Method: Compositional matrix adjust.
 Identities = 23/67 (34%), Positives = 33/67 (49%), Gaps = 4/67 (5%)
 Frame = +1

Query: 296 LYVKNLDDGIDDERLQKEFSPFGTITSTKVMTEGGRSKGFGFVCFSSPEEATKAVS---- 351
           L+V NL    D   L+  F P  T        +  + +GFGFV FS+P++A  A      
Sbjct: 94  LFVGNLSYDTDQYSLKDAF-PGATAARIAKFQDTQKPRGFGFVEFSTPDDAASAFDSGER 270

Query: 352 EMNGRIV 358
           E++GR V
Sbjct: 271 EVDGRQV 291
>28372
          Length = 398

 Score = 33.9 bits (76), Expect = 0.20,   Method: Composition-based stats.
 Identities = 16/33 (48%), Positives = 21/33 (63%)
 Frame = -2

Query: 138 KGHGFVHFETEEAAERAIEKMNGMLLNDRKVFV 170
           +G GFV F     AERA +KMNG ++  RK+ V
Sbjct: 259 QGFGFVTFAHSAEAERARDKMNGTVVEGRKIEV 161

 Score = 32.3 bits (72), Expect = 0.55,   Method: Composition-based stats.
 Identities = 14/33 (42%), Positives = 21/33 (63%)
 Frame = -2

Query: 333 KGFGFVCFSSPEEATKAVSEMNGRIVATKPLYV 365
           +GFGFV F+   EA +A  +MNG +V  + + V
Sbjct: 259 QGFGFVTFAHSAEAERARDKMNGTVVEGRKIEV 161
>10194
          Length = 1278

 Score = 32.7 bits (73), Expect = 0.45,   Method: Compositional matrix adjust.
 Identities = 20/67 (29%), Positives = 31/67 (46%)
 Frame = -3

Query: 12  SLYVGDLHPDVTEAMLYEKFSSAGPILSIRVYRDVITRRSLGYASVNFEQPADAERALDT 71
           S++VG+L  D+ E  +   F   G + +IRV RD  T    G   + F+       AL  
Sbjct: 403 SVFVGNLPFDIEEESVRSHFEDCGDVENIRVVRDRKTNLGKGICYILFKSADSVSLALKL 224

Query: 72  MNFDVIK 78
            N ++ K
Sbjct: 223 NNSELEK 203
>11019
          Length = 552

 Score = 31.6 bits (70), Expect = 0.99,   Method: Compositional matrix adjust.
 Identities = 16/38 (42%), Positives = 21/38 (55%), Gaps = 2/38 (5%)
 Frame = -1

Query: 308 ERLQKEFSPFGTITSTKVMTE--GGRSKGFGFVCFSSP 343
           E L+  F  FG I  + VM +    RS+GFGFV +  P
Sbjct: 522 ETLRSYFEKFGEIKESMVMKDPTSKRSRGFGFVTYKDP 409
>12350
          Length = 975

 Score = 31.6 bits (70), Expect = 1.0,   Method: Compositional matrix adjust.
 Identities = 23/74 (31%), Positives = 39/74 (52%), Gaps = 5/74 (6%)
 Frame = -2

Query: 288 SIRYQGINLYVKNLDDGIDDERLQKEFSPFGTITSTKVMTE--GGRSKGFGFVCFSSPEE 345
           S R +  +L V  L     ++ L+  FS FG +   +V  +   G+SKGFGF+ F+  E 
Sbjct: 638 SSRQKCSDLIVLGLPWKSTEDDLRSYFSQFGDLLMVQVKKDPKTGQSKGFGFIRFAEYES 459

Query: 346 ATKAVSE---MNGR 356
             K +++   ++GR
Sbjct: 458 QLKCMAQRHMIDGR 417
>25632
          Length = 864

 Score = 31.2 bits (69), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 14/39 (35%), Positives = 20/39 (51%)
 Frame = -2

Query: 122 FGNILSCKVVSDENGSKGHGFVHFETEEAAERAIEKMNG 160
           +G +  C V+      K +GFVH  T+  A  AI  +NG
Sbjct: 698 YGTVEECDVL------KNYGFVHMPTKSEASAAITNLNG 600
>03097
          Length = 1401

 Score = 31.2 bits (69), Expect = 1.4,   Method: Compositional matrix adjust.
 Identities = 18/61 (29%), Positives = 29/61 (47%), Gaps = 1/61 (1%)
 Frame = +1

Query: 317 FGTITSTKVMTE-GGRSKGFGFVCFSSPEEATKAVSEMNGRIVATKPLYVALAQRKEERQ 375
           +G I    +    G    G  +V F   E+A KAV+++N R    +P+Y  L    + R+
Sbjct: 187 YGEIEEMNICDNLGDHLVGNVYVKFRKEEDADKAVADLNNRWFNGRPIYAELTPVTDFRE 366

Query: 376 A 376
           A
Sbjct: 367 A 369

 Score = 28.1 bits (61), Expect = 9.9,   Method: Compositional matrix adjust.
 Identities = 16/63 (25%), Positives = 28/63 (44%)
 Frame = +1

Query: 200 DRMDDETLNGLFGRFGQILSVKVMTDEXXXXXXXXXXXXERHEDAQKAVDEMNGKELNGK 259
           D   +E    L  ++G+I  + +  +              + EDA KAV ++N +  NG+
Sbjct: 145 DDFFEEIFIELAEKYGEIEEMNICDNLGDHLVGNVYVKFRKEEDADKAVADLNNRWFNGR 324

Query: 260 HIY 262
            IY
Sbjct: 325 PIY 333
>12096
          Length = 1585

 Score = 30.0 bits (66), Expect = 2.7,   Method: Compositional matrix adjust.
 Identities = 13/29 (44%), Positives = 18/29 (62%)
 Frame = -3

Query: 330  GRSKGFGFVCFSSPEEATKAVSEMNGRIV 358
            G S+GFGFV F S  EA + +    G++V
Sbjct: 1109 GASRGFGFVEFQSQSEAQRWMDHNQGQVV 1023
>11579
          Length = 1307

 Score = 30.0 bits (66), Expect = 2.7,   Method: Compositional matrix adjust.
 Identities = 14/38 (36%), Positives = 23/38 (60%)
 Frame = +3

Query: 51 SLGYASVNFEQPADAERALDTMNFDVIKGKPVRIMWSQ 88
          S G+A V F    DAE A+D+M+  ++ G+ VR   ++
Sbjct: 3  SRGFAFVRFYDRRDAEDAMDSMDGALLDGREVRCQMAR 116
>15931
          Length = 447

 Score = 30.0 bits (66), Expect = 2.8,   Method: Compositional matrix adjust.
 Identities = 30/77 (38%), Positives = 35/77 (45%), Gaps = 3/77 (3%)
 Frame = -1

Query: 317 FGTITSTKVMTEG-GRSKGFGFVCFSSPEEATKAV--SEMNGRIVATKPLYVALAQRKEE 373
           FG   +T    EG GR         SSP  AT+AV  S   GR+ A    +VAL Q  EE
Sbjct: 306 FGVRGTTTWWQEG*GRQA-------SSPS-ATQAV*ASFAGGRVSAVATNHVALVQLAEE 151

Query: 374 RQAHLTNQYIQRMASVR 390
             AH   Q + R   VR
Sbjct: 150 GMAHGLTQAVARADLVR 100
>04988
          Length = 705

 Score = 29.6 bits (65), Expect = 3.7,   Method: Compositional matrix adjust.
 Identities = 17/77 (22%), Positives = 36/77 (46%)
 Frame = -3

Query: 293 GINLYVKNLDDGIDDERLQKEFSPFGTITSTKVMTEGGRSKGFGFVCFSSPEEATKAVSE 352
           G  +Y+  L     ++ +++ F  +G +    +        G+GFV F    +A  AV E
Sbjct: 655 GTRVYIGRLPYQAREKDIERFFRGYGRVNDIML------KNGYGFVEFEDFRDADDAVYE 494

Query: 353 MNGRIVATKPLYVALAQ 369
           +NG+ +  + + +  A+
Sbjct: 493 LNGKDLCGERVIIEHAR 443
>23720
          Length = 739

 Score = 29.6 bits (65), Expect = 4.2,   Method: Compositional matrix adjust.
 Identities = 17/77 (22%), Positives = 36/77 (46%)
 Frame = -1

Query: 293 GINLYVKNLDDGIDDERLQKEFSPFGTITSTKVMTEGGRSKGFGFVCFSSPEEATKAVSE 352
           G  +Y+  L     ++ +++ F  +G +    +        G+GFV F    +A  AV E
Sbjct: 688 GTRVYIGRLPYQAREKDIERFFRGYGRVNDIML------KNGYGFVEFEDFRDADDAVYE 527

Query: 353 MNGRIVATKPLYVALAQ 369
           +NG+ +  + + +  A+
Sbjct: 526 LNGKDLCGERVIIEHAR 476
>00741
          Length = 1846

 Score = 28.9 bits (63), Expect = 5.7,   Method: Compositional matrix adjust.
 Identities = 14/27 (51%), Positives = 16/27 (59%)
 Frame = -3

Query: 337  FVCFSSPEEATKAVSEMNGRIVATKPL 363
            FV FS  EE  KAVS +NGR    + L
Sbjct: 1430 FVEFSKQEELEKAVSSLNGRFFGGRVL 1350
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|170763470|ref|NP_056616.2| patatin-like phospholipase
domain containing 6 [Mus musculus]
         (1327 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

07814                                                                 536   e-152
27853                                                                 325   7e-89
20517                                                                  39   0.010
08195                                                                  35   0.30 
27710                                                                  33   0.74 
07494                                                                  33   1.1  
32085                                                                  32   2.0  
01994                                                                  32   2.2  
>07814
          Length = 1888

 Score =  536 bits (1382), Expect = e-152,   Method: Compositional matrix adjust.
 Identities = 239/381 (62%), Positives = 300/381 (78%), Gaps = 1/381 (0%)
 Frame = -3

Query: 879  WCSGHLHLRCPRRLFSRRSPAKLHELYEKVFSRRADRHSDFSRLARVLTGNTIALVLGGG 938
            WCS   H+RC +R+FSRR P K+ ++Y+K+F   ADR +D SRLAR LTG +I LVLGGG
Sbjct: 1886 WCSSFHHIRCNKRVFSRRPPDKMEQIYKKLFESEADRMTDVSRLARFLTGTSIGLVLGGG 1707

Query: 939  GARGCSHIGVLKALEEAGVPVDLVGGTSIGSFIGALYAEERSASRTKQRAREWAKSMTSV 998
            GARG +H+G++KA++EAG+P+D++GGTS+GSFIGAL+AEER   +   R +EWA  MTS+
Sbjct: 1706 GARGVAHVGMIKAMQEAGIPIDMIGGTSMGSFIGALWAEERQYPKFNIRGKEWAMKMTSI 1527

Query: 999  LEPVLDLTYPVTSMFTGSAFNRSIHRVFQDKQIEDLWLPYFNVTTDITASAMRVHKDGSL 1058
             + VLDLTYP TSMFTGS+FN +I   F  +QIEDLW+PYF VTTDIT+S+MR+H  GSL
Sbjct: 1526 WKKVLDLTYPYTSMFTGSSFNETIESTFPSRQIEDLWIPYFCVTTDITSSSMRIHTTGSL 1347

Query: 1059 WRYVRASMTLSGYLPPLCDPKDGHLLMDGGYINNLPADIARSMGAKTVIAIDVGSQDETD 1118
            WRYVRASM+LSGYLPPLCDP DGHLL+DGGY+NNLPAD+ R+MGA+T+ AIDVGSQDE++
Sbjct: 1346 WRYVRASMSLSGYLPPLCDPNDGHLLLDGGYVNNLPADVLRTMGARTIFAIDVGSQDESN 1167

Query: 1119 LSTYGDSLSGWWLLWKRLNPWADKVKVPDMAEIQSRLAYVSCVRQLEVVKSSSYCEYLRP 1178
            L+ YGD LSGWWLLWKR NPW+ KVKVPDM EIQSRLAYVSC RQLEVVK+S +CEY+RP
Sbjct: 1166 LTNYGDRLSGWWLLWKRWNPWSSKVKVPDMTEIQSRLAYVSCTRQLEVVKNSDWCEYIRP 987

Query: 1179 SIDCFKTMDFGKFDQIYDVGYQYGKAVFGGWTRGEVIEKMLTDRRSTDLNESRRADILAF 1238
             ID + T+ FG +D I DVGY +G  +  GW +G +I+ + T+++  D     RA     
Sbjct: 986  PIDKYGTLQFGSYDDIVDVGYNHGTTLLSGWIKGGLIKNLFTEKQKVDTRAPERAQQTKL 807

Query: 1239 PSSG-FTDLAEIVSRIEPPTS 1258
            P    FTDLAE+VSRI+ P S
Sbjct: 806  PVMAYFTDLAELVSRIDKPHS 744
>27853
          Length = 864

 Score =  325 bits (834), Expect = 7e-89,   Method: Compositional matrix adjust.
 Identities = 163/286 (56%), Positives = 202/286 (70%), Gaps = 4/286 (1%)
 Frame = +2

Query: 526 FVAQPGELVGQLAVLTGEPLIFTLRAQRDCTFLRISKSHFYEIMRAQPSVVLSAAHTVAA 585
           F   PGE+   L VLTGEP  FT RA+ D   + I+K++FY +MR +P +VL+       
Sbjct: 2   FSVTPGEMTDMLPVLTGEPSFFTTRAKTDMLLVLITKANFYSMMREEPFIVLNLGRMTVR 181

Query: 586 RMSPFVRQMDFAIDWTAVEAGRALYRQGDRSDCTYIVLNGRLRSVIQRGSGKKELVGEYG 645
           RMSPFVRQ+DFA+DW   EAG+AL+RQGD SD  YIVL GRLRSVI    GKKE+VGEYG
Sbjct: 182 RMSPFVRQIDFALDWQMTEAGKALFRQGDNSDSVYIVLTGRLRSVITLLGGKKEVVGEYG 361

Query: 646 RGDLIGVVEALTRQPRATTVHAVRDTELAKLPEGTLGHIKRRYPQVVTRLIHLLSQKILG 705
           RG+L+G+VE LT   RATT  A+RDTE+AK+PE  L  IK +YPQVVTRLIHLL Q+ILG
Sbjct: 362 RGELVGIVEVLTHTERATTNMAIRDTEVAKIPEELLTLIKLKYPQVVTRLIHLLGQRILG 541

Query: 706 NLQQLQGPFPGSGLSVPQHSE--LTNPA--SNLSTVAILPVCAEVPMMAFTLELQHALQA 761
           NLQ          +   ++ E  L NPA  +NL+TVA++P    VP+  FT+ELQHAL A
Sbjct: 542 NLQNRNTVALDQSMPFSRNGEGTLENPAIVNNLATVAVVPASESVPVDNFTMELQHALSA 721

Query: 762 IGPTLLLNSDVIRALLGASALDSIQEFRLSGWLAQQEDAHRIVLYQ 807
           IG T+ L SD+I++ LGA+ALD + EFRLS WL QQED  R+VLYQ
Sbjct: 722 IGSTIRLTSDIIKSQLGATALDGVNEFRLSSWLNQQEDIQRMVLYQ 859
>20517
          Length = 749

 Score = 39.3 bits (90), Expect = 0.010,   Method: Compositional matrix adjust.
 Identities = 39/148 (26%), Positives = 59/148 (39%), Gaps = 15/148 (10%)
 Frame = +3

Query: 501 SLHFVLWGCLHVYQRMIDKAEEVCLFVAQPGELVGQLAVLTGEPLIFTLRAQRDCTFLRI 560
           S +F+L G + V Q     +    L     G   G+LAV+TG     T+    +   L I
Sbjct: 18  SFYFILSGTVVVTQFERQYSTTRTLVTLDQGMSFGELAVITGSRRQATVSTMTEVELLCI 197

Query: 561 SKSHFYEI-MRAQPSVVLSAAHTVAARMSPFVRQMDFAIDWTA--------------VEA 605
           S   F +I M     ++    H      + F+R +DF   W                   
Sbjct: 198 SAKDFEDIFMAGGRKIITDPDH------NKFLRSVDFLKAWPVQQLAQHPHACMFHYFNR 359

Query: 606 GRALYRQGDRSDCTYIVLNGRLRSVIQR 633
           G+ L R  + SD  YIV +G L SV+++
Sbjct: 360 GQVLVRDSNNSDWIYIVKSGSL-SVMKK 440
>08195
          Length = 2165

 Score = 34.7 bits (78), Expect = 0.30,   Method: Compositional matrix adjust.
 Identities = 19/66 (28%), Positives = 31/66 (46%)
 Frame = -3

Query: 602  AVEAGRALYRQGDRSDCTYIVLNGRLRSVIQRGSGKKELVGEYGRGDLIGVVEALTRQPR 661
            +V+ G  +  QGD  D  Y++ +G     +    G+ +LVG Y      G +  +   PR
Sbjct: 1560 SVQPGEHIIDQGDDGDNFYVIDSGTYDIYVDV-EGQAKLVGNYDNSGFFGELALMYNMPR 1384

Query: 662  ATTVHA 667
            A T+ A
Sbjct: 1383 AATIIA 1366
>27710
          Length = 429

 Score = 33.1 bits (74), Expect = 0.74,   Method: Composition-based stats.
 Identities = 31/142 (21%), Positives = 61/142 (42%), Gaps = 8/142 (5%)
 Frame = +2

Query: 492 IARQGDQDVSLHFVLWGCLHVYQRMIDKAEEVCLFVAQPGELVGQLAVLTGEPLIFTLRA 551
           I +QGD+  + + +  G + V+        E+   +++ G   G+LA++ G P   T+RA
Sbjct: 8   IIQQGDEGDNFYVIDVGEVDVFVN-----SELVTTISEGGSF-GELALIYGTPRAATVRA 169

Query: 552 QRDCTFLRISKSHFYEIMRAQPSVVLSAAHTVAARMSPFVRQMDF--------AIDWTAV 603
           + D     I +  +  I+               +R+S  +  +D         +++  A 
Sbjct: 170 KSDVKLWGIDRDSYRRILMGSTIRKRKMYEEFLSRVS-ILESLDKWERLTVADSLETCAF 346

Query: 604 EAGRALYRQGDRSDCTYIVLNG 625
           + G  + +QG   D  YI+L G
Sbjct: 347 DDGETIVKQGAAGDDFYIILEG 412
>07494
          Length = 512

 Score = 32.7 bits (73), Expect = 1.1,   Method: Composition-based stats.
 Identities = 17/44 (38%), Positives = 24/44 (54%), Gaps = 1/44 (2%)
 Frame = +2

Query: 1216 EKMLTDRRSTDLNESRRADILAFPSSG-FTDLAEIVSRIEPPTS 1258
            + + T+++  D     RA     P    FTDLAE+VSRI+ P S
Sbjct: 2    KNLFTEKQKVDTRAPERAQQTKLPVMAYFTDLAELVSRIDKPHS 133
>32085
          Length = 1641

 Score = 31.6 bits (70), Expect = 2.0,   Method: Composition-based stats.
 Identities = 13/40 (32%), Positives = 18/40 (45%), Gaps = 1/40 (2%)
 Frame = -1

Query: 146 RVLGHFEKPLFLELCRHM-VFQRLGQGDYVFRPGQPDASI 184
           R + HF +PLF   C HM ++ +     YV  P      I
Sbjct: 522 RCIRHFTRPLFAHTCTHMFIYMQTSNSSYVLTPAAHSGQI 403
>01994
          Length = 1090

 Score = 31.6 bits (70), Expect = 2.2,   Method: Compositional matrix adjust.
 Identities = 16/41 (39%), Positives = 20/41 (48%)
 Frame = -2

Query: 330 DTSKETSGRPLDSIGAPLPGPAGDPVKPTSLEAPPAPLLSR 370
           D   + S  P+D    PLP  A  PV PT ++  P P L R
Sbjct: 471 DAPPDYSTVPMDFEPVPLPKTASVPVNPTKVKLNPRPWLER 349
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|125656173|ref|NP_579938.2| acetyl-Coenzyme A
carboxylase alpha [Mus musculus]
         (2345 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

27198                                                                 412   e-150
30077                                                                 252   1e-66
15060                                                                 155   2e-37
31960                                                                  34   0.84 
27046                                                                  33   1.3  
22538                                                                  30   9.4  
>27198
          Length = 1148

 Score =  412 bits (1058), Expect(2) = e-150,   Method: Compositional matrix adjust.
 Identities = 191/261 (73%), Positives = 228/261 (87%)
 Frame = +1

Query: 1672 DGRDIIVIGNDITYRIGSFGPQEDLLFLRASELARAEGIPRIYVAANSGARIGLAEEIRH 1731
            +GRDIIVI ND+T+RIGSFGPQEDLLF +ASE +R +G+PRI+++ANSGARIGLAEEI+ 
Sbjct: 364  EGRDIIVIANDMTWRIGSFGPQEDLLFKKASEYSRKKGLPRIFISANSGARIGLAEEIKS 543

Query: 1732 MFHVAWVDPEDPYKGYKYLYLTPQDYKRVSALNSVHCEHVEDEGESRYKITDIIGKEEGL 1791
            +FHVAW +P+ P +G+KYLYL P ++K+VSA+NSV  E ++DEGESRYKITDIIGKEEGL
Sbjct: 544  LFHVAWENPDKPDQGFKYLYLRPDEFKKVSAMNSVRAELIQDEGESRYKITDIIGKEEGL 723

Query: 1792 GAENLRGSGMIAGESSLAYDEVITISLVTCRAIGIGAYLVRLGQRTIQVENSHLILTGAG 1851
            G ENLRGSGMIAGE+S AYDEV+TI+LVTCRAIGIGAYLVRLGQR IQVENSH+ILTGA 
Sbjct: 724  GVENLRGSGMIAGETSAAYDEVVTINLVTCRAIGIGAYLVRLGQRVIQVENSHIILTGAS 903

Query: 1852 ALNKVLGREVYTSNNQLGGIQIMHNNGVTHSTVCDDFEGVFTVLHWLSYMPKSVHSSVPL 1911
            ALNKVLGREVYTSNNQLGGIQIM+NNGVTH+ V DDF GV  +LHWLSY+PK     +P+
Sbjct: 904  ALNKVLGREVYTSNNQLGGIQIMYNNGVTHAVVQDDFAGVHKILHWLSYIPKHRXGPLPV 1083

Query: 1912 LNSKDPIDRIIEFVPTKAPYD 1932
                DP++R +EF+PTK PY+
Sbjct: 1084 XEPVDPVERDVEFMPTKTPYN 1146

 Score =  140 bits (353), Expect(2) = e-150,   Method: Composition-based stats.
 Identities = 63/119 (52%), Positives = 86/119 (72%)
 Frame = +2

Query: 1552 TAQIMFQAYGDKQGPLHGMLINTPYVTKDLLQSKRFQAQSLGTTYIYDIPEMFRQSLIKL 1611
            T QIMF++YG K+GPLHG+LI+TPY TKD LQ KRFQAQS GTTY+YD P++F+Q+L+  
Sbjct: 2    TGQIMFESYGTKRGPLHGLLISTPYQTKDQLQLKRFQAQSSGTTYVYDYPDIFKQALLHQ 181

Query: 1612 WESMSTQAFLPSPPLPSDILTYTELVLDDQGQLVHMNRLPGGNEIGMVAWKMSLKSPEY 1670
            W     +  +       D +T  E++LD + QL   +RLPG N++GMV WKM+LK+PE+
Sbjct: 182  WTEYDKKHGVKEERNGLDFITCVEMMLDSREQLSPCHRLPGDNQVGMVVWKMTLKTPEF 358
>30077
          Length = 575

 Score =  252 bits (644), Expect = 1e-66,   Method: Compositional matrix adjust.
 Identities = 119/157 (75%), Positives = 136/157 (86%), Gaps = 2/157 (1%)
 Frame = +1

Query: 1955 DYGSFSEIMQPWAQTVVVGRARLGGIPVGVVAVETRTVELSIPADPANLDSEAKIIQQAG 2014
            D GSF EI++PWA+TVVVGRARLGGIPVGVV VETRTVEL++PADPANLDSE KI+QQAG
Sbjct: 1    DDGSFDEILKPWAETVVVGRARLGGIPVGVVCVETRTVELTVPADPANLDSETKIVQQAG 180

Query: 2015 QVWFPDSAFKTYQAIKDFNREGLPLMVFANWRGFSGGMKDMYDQVLKFGAYIVDGLRECS 2074
            QVWFPDSA+KT QAIKDF RE LPL++FANWRGFSGGMKDMYDQVLKFG+YIVD LRE  
Sbjct: 181  QVWFPDSAYKTAQAIKDFAREQLPLIIFANWRGFSGGMKDMYDQVLKFGSYIVDALREYR 360

Query: 2075 QPVMVYIPPQAELRGGS--WVVIDPTINPRHMEMYAD 2109
            QPV++YIPP  ELRGG   W ++   + P HM+M+AD
Sbjct: 361  QPVLIYIPPYGELRGGRG*WSIL--PLTPDHMDMFAD 465
>15060
          Length = 935

 Score =  155 bits (392), Expect = 2e-37,   Method: Compositional matrix adjust.
 Identities = 111/342 (32%), Positives = 167/342 (48%), Gaps = 4/342 (1%)
 Frame = -2

Query: 208 WGHASENPKLPELLLKNGIAFMGPPSQAMWALGDKIASSIVAQTAGIPTLPWSGSGLRVD 267
           +G  SE P   +  +  GI F+GP  + +  +GDK+ +   A  AG+  +P +       
Sbjct: 934 YGFLSERPDFAQACVDAGIHFVGPSPEVVHRMGDKVEARQSAINAGVQVVPGT------- 776

Query: 268 WQENDFSKRILNVPQDLYEKGYVKDVDDGLKAAEEVGYPVMIKASEGGGGKGIRKVNN-- 325
                               G V   ++ ++  +E G PV+ KA+ GGGG+G+R V N  
Sbjct: 775 -------------------PGPVASAEEAMEFCKEHGLPVIFKAAFGGGGRGMRVVRNLE 653

Query: 326 --ADDFPNLFRQVQAEVPGSPIFVMRLAKQSRHLEVQILADQYGNAISLFGRDCSVQRRH 383
              ++F   F +  A      +F+ +  ++ RH+EVQ+L D+ GN I L+ RDCSVQRRH
Sbjct: 652 EVEENFNRAFSEALAAFGDGSLFIEKFIERPRHIEVQLLGDRTGNVIHLYERDCSVQRRH 473

Query: 384 QKXXXXXXXXXXXXXVFEHMEQCAVKLAKMVGYVSAGTVEYLYSQDGSFYFLELNPRLQV 443
           QK             V   M   AV+LAK VGY +AGTVE+L  ++G +YF+E+N RLQV
Sbjct: 472 QKVVEIAPAPQLDSEVRTKMANDAVRLAKFVGYENAGTVEFLLDKNGQYYFIEVNARLQV 293

Query: 444 EHPCTEMVADVNLPAAQLQIAMGIPLFRIKDIRMMYGVSPWGDAPIDFENSAHVPCPRGH 503
           EH  TE V  V+L  AQ++IA G  L                    D + +       G 
Sbjct: 292 EHTVTEQVTGVDLVQAQIRIAEGKTL-------------------SDLDLTQDKIQLNGC 170

Query: 504 VIAARITSENPDEGFKPSSGTVQELNFRSNKNVWGYFSVAAA 545
            I  R+T+E+P   F+P +G ++   FRS + +      A+A
Sbjct: 169 AIQCRMTTEDPARNFQPDTGRIE--VFRSGEGMGIRLDSASA 50
>31960
          Length = 667

 Score = 33.9 bits (76), Expect = 0.84,   Method: Compositional matrix adjust.
 Identities = 17/45 (37%), Positives = 28/45 (62%)
 Frame = -2

Query: 569 AISNMVVALKELSIRGDFRTTVEYLIKLLETESFQLNRIDTGWLD 613
           A S M+ ALKE  IRG  +T + +L+ +L+ + F    +DT ++D
Sbjct: 624 ASSKMLRALKEFRIRG-VKTNIPFLLNVLQNDKFLTGVVDTYFID 493
>27046
          Length = 388

 Score = 33.1 bits (74), Expect = 1.3,   Method: Composition-based stats.
 Identities = 17/52 (32%), Positives = 33/52 (63%), Gaps = 2/52 (3%)
 Frame = +1

Query: 644 RNSISNFLHSLERGQ--VLPAHTLLNTVDVELIYEGIKYVLKVTRQSPNSYV 693
           RN +S+  ++ +RG+   +  H ++N +D+++  +    + KVTR +PNSYV
Sbjct: 34  RNVLSDTEYTTKRGK*NCITEHNIINYLDMKMTSK----MFKVTRSTPNSYV 177
>22538
          Length = 1255

 Score = 30.4 bits (67), Expect = 9.4,   Method: Composition-based stats.
 Identities = 25/89 (28%), Positives = 38/89 (42%), Gaps = 4/89 (4%)
 Frame = -3

Query: 1111 GHQFCIENLQKLILSETSIFDVLPNFFYHSNQVVRMAALEVYVRRAYIAYELNSVQHRQL 1170
            G Q C E  +K+ILS   + +  PN    + Q  R  +L V+V+   +    N ++H   
Sbjct: 506  GQQACFEKTKKMILSAKVLVNYYPN-XPDNFQFQRKXSLVVHVKNTSVP---NCMEHTDR 339

Query: 1171 KDNTCV----VEFQFMLPTSHPNRGNIPT 1195
                C     VE+   L   HP   + PT
Sbjct: 338  NQPFCSFLHQVEYDTTLHCLHPFPKSSPT 252
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|19882201|ref|NP_598862.1| proteasome 26S non-ATPase
subunit 2 [Mus musculus]
         (908 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

05493                                                                 468   e-150
05545                                                                 288   e-100
32303                                                                  29   0.029
>05493
          Length = 1292

 Score =  468 bits (1203), Expect(2) = e-150,   Method: Compositional matrix adjust.
 Identities = 218/337 (64%), Positives = 275/337 (81%)
 Frame = -2

Query: 49   DKQLQDELEMLVERLGEKDTSLYRPALEELRRQIRSSTTSMTSVPKPLKFLRPHYGKLKE 108
            D+QLQ+EL MLVERL E D  LY+ ALE LR  IR+STTSMTSVPKPLKFLRPHY  +K+
Sbjct: 1165 DRQLQEELTMLVERLQEPDQRLYKAALESLRVLIRASTTSMTSVPKPLKFLRPHYDTMKQ 986

Query: 109  IYENMAPGENKCFAADIISVLAMTMSGERECLKYRLVGSQEELASWGHEYVRHLAGEVAK 168
            I+E +   E K F ADIISVL MTMS  R+ L Y+  GS+EE+ +WGHEYVRHLAG+VA+
Sbjct: 985  IHEKIRDQETKEFCADIISVLGMTMSEGRDSLHYKQQGSKEEIGAWGHEYVRHLAGQVAQ 806

Query: 169  EWQELDDAEKAQREPLLTLVKEIVPYNMAHNAEHEACDLLMEIEQVDMLEKDIDENAYAK 228
            EWQ   + +K  ++ L+ L K+I+PY+M HNAE EACDL+ME+E++D+  + +DE AY++
Sbjct: 805  EWQVTGEDDKEMKDKLIGLAKQIIPYHMHHNAEAEACDLMMEVERLDLAMEYVDEQAYSR 626

Query: 229  VCLYLTSCVNYVPEPENSALLRCALGVFRKFSRFPEALRLALMLNDMELVEDIFTSCKDV 288
            VCLYLTSCV YVP+PEN+ALLRCA+ ++RKF +FP+ALR AL LNDM+L+EDIF SCKD+
Sbjct: 625  VCLYLTSCVAYVPDPENTALLRCAVDLYRKFKQFPQALRFALQLNDMKLIEDIFVSCKDL 446

Query: 289  VVQKQMAFMLGRHGVFLELSEDVEEYEDLTEIMSNVQLNSNFLALARELDIMEPKVPDDI 348
            V+QKQ+A+MLGR  +F+EL++D+EE ++LTEIMSN  LN  FL+LARELDIMEPKVP+DI
Sbjct: 445  VMQKQLAYMLGRQQIFMELNDDIEESDELTEIMSNAPLNGAFLSLARELDIMEPKVPEDI 266

Query: 349  YKTHLENNRFGGSGSQVDSARMNLASSFVNGFVNAAF 385
            YK+HLE NR     + +DSAR NLASSFVNGFVNAAF
Sbjct: 265  YKSHLEPNRTALGANNLDSARQNLASSFVNGFVNAAF 155

 Score = 84.3 bits (207), Expect(2) = e-150,   Method: Composition-based stats.
 Identities = 37/45 (82%), Positives = 40/45 (88%)
 Frame = -3

Query: 385 FGQDKLLTDDGNKWLYKNKDHGMLSAAASLGMILLWDVDGGLTQI 429
           FGQDKLL +DGNKWLYKNK+HGMLSA ASLG+ILLW VD GL QI
Sbjct: 156 FGQDKLLMEDGNKWLYKNKEHGMLSATASLGLILLWXVDXGLIQI 22
>05545
          Length = 1952

 Score =  288 bits (737), Expect(2) = e-100,   Method: Compositional matrix adjust.
 Identities = 140/200 (70%), Positives = 159/200 (79%)
 Frame = -1

Query: 642  APADMGAHQGVAVLGIALIAMGEEIGAEMALRTFGHLLRYGEPTLRRAVPLALALISVSN 701
            A  D+   QG+AVLGI LIAMGEEIG+EM+ R+FGHLLRYGE  +RRAVPLALALISVSN
Sbjct: 1799 AGPDLSLQQGIAVLGIGLIAMGEEIGSEMSYRSFGHLLRYGELPIRRAVPLALALISVSN 1620

Query: 702  PRLNILDTLSKFSHDADPEVSYNSIFAMGMVGSGTNNXXXXXXXXXXXXYHAKDPNNLFM 761
            P+L ILDTLSKFSHD+DPEV++N+I AMG+VG+GTNN            YHAKDPNNLF+
Sbjct: 1619 PKLQILDTLSKFSHDSDPEVAHNAIMAMGIVGAGTNNARLAAMLRQLAVYHAKDPNNLFI 1440

Query: 762  VRLAQXXXXXXXXXXXXCPYHSDRQLMSQVAVAGLLTVLVSFLDVRNIILGKSHYVLYGL 821
            VRLAQ            CP+HSDR LMS VAVAGL+  L+S LDV+N+ILGKSHYVLY L
Sbjct: 1439 VRLAQGLTHLGKGTLTLCPFHSDRTLMSPVAVAGLMATLISCLDVKNLILGKSHYVLYNL 1260

Query: 822  VAAMQPRMLVTFDEELRPLP 841
            VAAMQPRMLVTFDEELRPLP
Sbjct: 1259 VAAMQPRMLVTFDEELRPLP 1200

 Score = 97.1 bits (240), Expect(2) = e-100,   Method: Compositional matrix adjust.
 Identities = 43/50 (86%), Positives = 49/50 (98%)
 Frame = -2

Query: 858  KPKTITGFQTHTTPVLLAHGERAELATEEFLPVTPILEGFVILRKNPNYD 907
            KPKTITGFQTHTTPVLLA+GERAELATEE+L +TPI+EGFVILRKNP+Y+
Sbjct: 1150 KPKTITGFQTHTTPVLLAYGERAELATEEYLTLTPIMEGFVILRKNPDYE 1001
>32303
          Length = 1266

 Score = 28.9 bits (63), Expect(2) = 0.029,   Method: Compositional matrix adjust.
 Identities = 19/58 (32%), Positives = 32/58 (55%), Gaps = 1/58 (1%)
 Frame = -2

Query: 473  NSNTMRLGSIFGLGLAYAGSNREDVL-TLLLPVMGDSKSSMEVAGVTALACGMIAVGS 529
            +++ +R G   GLGLA  G+ R+D+   L   +  D   + E AG   LA G++ +G+
Sbjct: 1079 STDMVRHGGCLGLGLAAMGTARQDIYEQLKFNLYQDDAVTGEAAG---LAMGLVMLGT 915

 Score = 26.9 bits (58), Expect(2) = 0.029,   Method: Compositional matrix adjust.
 Identities = 16/60 (26%), Positives = 25/60 (41%)
 Frame = -3

Query: 556 RWLPLGLGLNHLGKGXXXXXXXXXXXVVSEPFRSFANTLVDVCAYAGSGNVLKVQQLLHI 615
           R L +G+ L   G+               +P   +A       AY GSGN   +++LLH+
Sbjct: 847 RGLAVGIALTMYGRMEEADALVESLTRDKDPILRWAGMYTLAMAYCGSGNNQAIRRLLHV 668
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|21312352|ref|NP_082427.1| superkiller viralicidic
activity 2-like 2 [Mus musculus]
         (1040 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

13828                                                                 528   e-150
11624                                                                  31   2.9  
33603                                                                  30   5.1  
>13828
          Length = 2681

 Score =  528 bits (1360), Expect = e-150,   Method: Compositional matrix adjust.
 Identities = 258/411 (62%), Positives = 319/411 (77%)
 Frame = +2

Query: 630  QLAKLGKEIEEYIHKPKYCLPFLQPGRLVKVKNEGDDFGWGXXXXXXXXXXXXXXXGELD 689
            QL  L +++  YI KP Y LPFLQPGRL++VKN+ DDFGWG                +  
Sbjct: 2    QLDNLARDLRHYILKPIYLLPFLQPGRLIRVKNKDDDFGWGVVVSFQKKVDQSAATEDTG 181

Query: 690  PLYVVEVLLRCSKESLKNSATEAAKPAKPDEKGEMQVVPVLVHLLSAISTVRLYIPKDLR 749
            P+YVVE LL  S++S +  +T   KP    EKGEMQVVP+L  L+  +S +RLYIP DLR
Sbjct: 182  PIYVVETLLYLSRDSTRGRSTAHLKPCVKGEKGEMQVVPILTKLIQCLSAIRLYIPNDLR 361

Query: 750  PVDNRQSVLKSIQEVQRRFPDGVPLLDPIDDMGIQDQGLKKVIQKVEAFEHRMYSHPLHN 809
              ++R SVLKS+QEV++RF DGVP+LDP++DMGI+++GL  VI+K EAFEHR+++HPLH 
Sbjct: 362  SSEHRLSVLKSLQEVEKRFEDGVPVLDPLEDMGIKEKGLHDVIKKTEAFEHRLHTHPLHK 541

Query: 810  DPNLETVYTLCERKAQIALDIKSAKRELKKARTVLQMDELKCRKRVLRRLGFATSSDVIE 869
            D  L+ +Y   E+K   A +IK+ + ELKK +++LQMDELKCRKRVLRRLG+AT+SDVIE
Sbjct: 542  DXRLDXLYNSYEKKTSWANEIKALRLELKKKKSLLQMDELKCRKRVLRRLGYATASDVIE 721

Query: 870  MKGRVACEISSADELLLTEMMFNGLFNDLSSEQATALLSCFVFQENSSEMPKLTEQLAGP 929
             KGRVACEISS DEL++TE++FN +FNDLS  Q  ALLSCFVFQE +SE PKL E+L+GP
Sbjct: 722  TKGRVACEISSGDELVITELLFNNVFNDLSPAQCCALLSCFVFQERASETPKLIEELSGP 901

Query: 930  LRQMQECAKRIAKVSAEAKLEIDEETYLSSFKPHLMDVVYTWATGATFAHICKMTDVFEG 989
            LR MQE AKRIA+VS EAKLEIDE+ Y+ SF+P +MD+VY W  G +F+ ICKMTD+FEG
Sbjct: 902  LRLMQETAKRIARVSKEAKLEIDEDQYVESFRPQMMDIVYEWCNGCSFSKICKMTDIFEG 1081

Query: 990  SIIRCMRRLEELLRQMCQAAKAIGNTELENKFAEGITKIKRDIVFAASLYL 1040
            S+IRCMRRLEE LRQM QA+KAIGNTELENKFAEGI  IKRDIVFAASLYL
Sbjct: 1082 SVIRCMRRLEETLRQMVQASKAIGNTELENKFAEGIRLIKRDIVFAASLYL 1234
>11624
          Length = 2257

 Score = 30.8 bits (68), Expect = 2.9,   Method: Compositional matrix adjust.
 Identities = 21/80 (26%), Positives = 35/80 (43%), Gaps = 8/80 (10%)
 Frame = -3

Query: 153  QSVLVSAHTSAGKTVCAEYAIALALREKQ----RVIFTSPIKALSNQKYREMYEEFQD-- 206
            + + VSA T +GKT+     I   L+++     R +   P++ L+ Q Y+       D  
Sbjct: 1814 RDICVSAPTGSGKTLAYTLPIIQCLKQRMVPHVRAVIVLPVRDLAEQVYQVFCHYCADTP 1635

Query: 207  --VGLMTGDVTINPTASCLV 224
              VG++ G    N     LV
Sbjct: 1634 LKVGIVVGKTVFNVEQDTLV 1575
>33603
          Length = 441

 Score = 30.0 bits (66), Expect = 5.1,   Method: Compositional matrix adjust.
 Identities = 18/49 (36%), Positives = 23/49 (46%)
 Frame = +2

Query: 44  KRLDTKLQSESASGGKNKRDLDVEGTDEPIFGKKPRIEDSINEDLSLAD 92
           K++  K QSE +     + D D   TDE   G  PR   S N D  L+D
Sbjct: 101 KQMKIKTQSEESPSKPCRTDEDNATTDENKMGVNPRKRCSTNNDECLSD 247
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|21704120|ref|NP_663604.1| plastin 3 precursor [Mus
musculus]
         (630 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

09711                                                                 527   e-150
32088                                                                 309   2e-84
04951                                                                 172   3e-43
19002                                                                  44   2e-04
05237                                                                  44   3e-04
19147                                                                  40   0.004
14366                                                                  38   0.012
14594                                                                  37   0.024
29446                                                                  36   0.042
17613                                                                  35   0.11 
17504                                                                  33   0.34 
15966                                                                  33   0.48 
01019                                                                  32   0.75 
07198                                                                  32   1.1  
26896                                                                  31   1.7  
01773                                                                  30   2.9  
00115                                                                  30   3.9  
07153                                                                  29   5.9  
26610                                                                  29   6.3  
>09711
          Length = 3041

 Score =  527 bits (1358), Expect = e-150,   Method: Compositional matrix adjust.
 Identities = 276/523 (52%), Positives = 358/523 (68%), Gaps = 5/523 (0%)
 Frame = +1

Query: 108 GTSELSSEGTQHSYSEEEKYAFVNWINKALENDPDCRHVIPMNPNTDDLFKAVGDGIVLC 167
           GTS  SSEGT H+    E+ AF  WIN+ L + PDC+H++P++ +   LF  + DG++LC
Sbjct: 1   GTSYASSEGTTHTVKAGEQKAFAEWINRHLSDXPDCKHLLPLDADGTQLFGQMADGVLLC 180

Query: 168 KMINLSVPDTIDERAINKKKLTPFIIQENLNLALNSASAIGCHVVNIGAEDLRAGKPHLV 227
           K+IN SV +TIDER INK+ L+ +   ENL LA+NSA AIGC  VNIG EDL AG+PHLV
Sbjct: 181 KLINHSVSNTIDERTINKQNLSLYRRHENLTLAVNSAGAIGCTTVNIGPEDLAAGRPHLV 360

Query: 228 LGLLWQIIKIGLFADIELSRNEALAALLRDGETLEELMKLSPEELLLRWANFHLENSGW- 286
           LGLLWQII+IGL +DI L+ +  L  LL DGET+E+L++LSPE++LLRW N+HL  +G  
Sbjct: 361 LGLLWQIIRIGLLSDINLAHHPGLVNLLLDGETIEDLIRLSPEQILLRWVNYHLNRAGCD 540

Query: 287 QKINNFSADIKDSKAYFHLLNQIAPKGQKEGEPRIDINMSGFNETDDLKRAESMLQQADK 346
           ++I NF  DIKDS+AY HLL QI+P       P   + +S  +  D  +RAE MLQ+ADK
Sbjct: 541 RQIXNFGEDIKDSEAYTHLLKQISP-------PSAGVTLSPLSVGDVHQRAECMLQEADK 699

Query: 347 LGCRQFVTPADVVSGNPKLNLAFVANLFNKYPALTKPENQDIDWXXXXXXXXXXXXFRNW 406
           +GCR FV  +DVVSGN KLNLAFVANLFN YPAL  P+ +  D             +RNW
Sbjct: 700 IGCRSFVGASDVVSGNQKLNLAFVANLFNNYPALDTPQVEVED--VMKEESREEKTYRNW 873

Query: 407 MNSLGVNPHVNHLYADLQDALVILQLYERIKVP-VDWSKVNKPPYPKLGANMKKLENCNY 465
           MNSLGV+P V+HLY+DL D L+I QLY+ I+   VDWSKV K       A  +++ENCNY
Sbjct: 874 MNSLGVSPFVHHLYSDLYDGLIIFQLYDYIQPGLVDWSKVKKKFNKLK-ARFERIENCNY 1050

Query: 466 AVELGKNP--AKFSLVGIGGQDLNDGNPTLTLAVVWQLMRRYTLNVLEDLGEGQKA-NDD 522
           AVELG      K  LVGI GQD+ DGNP LTL +VWQLMR YTL +L  + E  K  +D+
Sbjct: 1051AVELGPQVKLVKVKLVGIAGQDILDGNPVLTLGLVWQLMRAYTLAILSKITENNKPISDN 1230

Query: 523 IIVNWVNRTLSEAGKSTSIQSFKDKTISSSLAVVDLIDAIQPGCINYDLVKSGNLTEDDK 582
            I+ WVN   S+  K   I  F+D+ ++  + V  +I+AI+PG +N+D +        D+
Sbjct: 1231EIITWVN---SKIKKDDRISGFQDRKLNDGVIVARVIEAIKPGIVNWDNIDCSARDYQDR 1401

Query: 583 HNNAKYAVSMARRIGARVYALPEDLVEVKPKMVMTVFACLMGR 625
             NA+YA+ +AR+IGA VYALPED+VEVKPKM++TVFACLM R
Sbjct: 1402LTNARYAIGLARKIGAGVYALPEDIVEVKPKMLLTVFACLMMR 1530
>32088
          Length = 1928

 Score =  309 bits (792), Expect = 2e-84,   Method: Compositional matrix adjust.
 Identities = 151/296 (51%), Positives = 209/296 (70%), Gaps = 5/296 (1%)
 Frame = +1

Query: 2    DEMA---TTQISKDELDELKEAFAKVDLNSNGFICDYELHELFKEANMPLPGYKVREIIQ 58
            D+MA   T  + +D+L EL+  F  +D ++NG I   EL   F+   + +PGY++R I+ 
Sbjct: 895  DKMAKRHTVALDEDQLTELRSVFDSIDDDNNGHISXGELDSAFRAVGLNIPGYELRTIMS 1074

Query: 59   KLMVDGDRNKDGKISFNEFVYIFQEVKSS-DIAKTFRKAINRKEGICALGGTSELSSEGT 117
            K     D + DG+++ +EF  ++   KS  DI  TF+KA++ ++G+  +GGTSE SSEGT
Sbjct: 1075 KY----DASGDGRLNMDEFRTLYASEKSKRDIGHTFKKAVSTRQGVATIGGTSEASSEGT 1242

Query: 118  QHSYSEEEKYAFVNWINKALENDPDCRHVIPMNPNTDDLFKAVGDGIVLCKMINLSVPDT 177
             H+  + E+ AF  WIN+ L++DPDC+H++ +N   DDLFK VGDGI+LCK+IN SV +T
Sbjct: 1243 THTVKDGEQKAFAAWINRHLKDDPDCKHLMEVNEEGDDLFKKVGDGILLCKLINHSVSNT 1422

Query: 178  IDERAINKKKLTPFIIQENLNLALNSASAIGCHVVNIGAEDLRAGKPHLVLGLLWQIIKI 237
            IDERAINK  L  +   ENL LA+NSA +IGC  VNIG EDL AG+PHLVLGLLWQII+I
Sbjct: 1423 IDERAINKSNLNVYHRHENLTLAVNSAGSIGCTTVNIGPEDLAAGRPHLVLGLLWQIIRI 1602

Query: 238  GLFADIELSRNEALAALLRDGETLEELMKLSPEELLLRWANFHLENSGW-QKINNF 292
            GL +DI L+ +  L  LLR+GET+E+ M+LSPEE+LLRW N+HLE +G  ++I NF
Sbjct: 1603 GLLSDINLAHHPGLVNLLREGETIEDFMRLSPEEILLRWVNYHLERAGTDRRIANF 1770

 Score = 40.0 bits (92), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 39/153 (25%), Positives = 63/153 (41%), Gaps = 20/153 (13%)
 Frame = +1

Query: 412  VNPHVNHLYADLQDALVILQLY-ERIKVPVDWSKVNKPPYPKLGANMKKLENCNYAVELG 470
            VN   + L+  + D +++ +L    +   +D   +NK           + EN   AV   
Sbjct: 1336 VNEEGDDLFKKVGDGILLCKLINHSVSNTIDERAINKSNLNV----YHRHENLTLAVN-S 1500

Query: 471  KNPAKFSLVGIGGQDLNDGNPTLTLAVVWQLMRRYTLNVLED------------LGEGQK 518
                  + V IG +DL  G P L L ++WQ++R   + +L D            L EG+ 
Sbjct: 1501 AGSIGCTTVNIGPEDLAAGRPHLVLGLLWQIIR---IGLLSDINLAHHPGLVNLLREGET 1671

Query: 519  AND-------DIIVNWVNRTLSEAGKSTSIQSF 544
              D       +I++ WVN  L  AG    I +F
Sbjct: 1672 IEDFMRLSPEEILLRWVNYHLERAGTDRRIANF 1770
>04951
          Length = 2852

 Score =  172 bits (436), Expect = 3e-43,   Method: Compositional matrix adjust.
 Identities = 88/173 (50%), Positives = 120/173 (69%), Gaps = 3/173 (1%)
 Frame = +1

Query: 458 KKLENCNYAVELGKN--PAKFSLVGIGGQDLNDGNPTLTLAVVWQLMRRYTLNVLEDLGE 515
           +K+ENC YAV+LG      K  LVGIGG+D++DGNP LTL +VWQLMR YTL +L  L E
Sbjct: 1   EKIENCEYAVQLGPQMKVCKMKLVGIGGKDIHDGNPVLTLGLVWQLMRAYTLAILSKLTE 180

Query: 516 GQKA-NDDIIVNWVNRTLSEAGKSTSIQSFKDKTISSSLAVVDLIDAIQPGCINYDLVKS 574
            +K   D  IV+WVN   S+  K   I SF+D  ++  + V  +I++I+PG +N++ +  
Sbjct: 181 DKKPIQDSEIVDWVN---SKVKKDERIGSFQDSKLNDGVIVAKVIESIKPGIVNWENINP 351

Query: 575 GNLTEDDKHNNAKYAVSMARRIGARVYALPEDLVEVKPKMVMTVFACLMGRGM 627
                DD+  NA+YA+ +AR+IGA VYALPED+VEVKPKM++TVFACLM R +
Sbjct: 352 NASEPDDRLANARYAIGLARKIGAGVYALPEDIVEVKPKMLLTVFACLMMRDL 510

 Score = 43.9 bits (102), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 41/165 (24%), Positives = 71/165 (43%), Gaps = 1/165 (0%)
 Frame = +1

Query: 211 VVNIGAEDLRAGKPHLVLGLLWQIIKIGLFADIELSRNEALAALLRDGETLEELMKLSPE 270
           +V IG +D+  G P L LGL+WQ+++    A         L+ L  D + ++       +
Sbjct: 67  LVGIGGKDIHDGNPVLTLGLVWQLMRAYTLA--------ILSKLTEDKKPIQ-------D 201

Query: 271 ELLLRWANFHLENSGWQKINNFS-ADIKDSKAYFHLLNQIAPKGQKEGEPRIDINMSGFN 329
             ++ W N  ++    ++I +F  + + D      ++  I P G    E   +IN +   
Sbjct: 202 SEIVDWVNSKVKKD--ERIGSFQDSKLNDGVIVAKVIESIKP-GIVNWE---NINPNASE 363

Query: 330 ETDDLKRAESMLQQADKLGCRQFVTPADVVSGNPKLNLAFVANLF 374
             D L  A   +  A K+G   +  P D+V   PK+ L   A L 
Sbjct: 364 PDDRLANARYAIGLARKIGAGVYALPEDIVEVKPKMLLTVFACLM 498
>19002
          Length = 842

 Score = 43.9 bits (102), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 53/230 (23%), Positives = 94/230 (40%), Gaps = 11/230 (4%)
 Frame = -2

Query: 162 DGIVLCKMINLSVPDTIDERAINKKKLTPFIIQENLNLALNSASAIGCHVVNIGAEDLRA 221
           DG +L K++ + V   I      K ++      EN++ AL        H+ N+GA D+  
Sbjct: 841 DGKMLMKLLEVRVRGEIASDXKGKMRIHCL---ENVDKALTFLHEQRVHLENMGAHDIVD 671

Query: 222 GKPHLVLGLLWQIIKIGLFADIELSRNEALAALLRDGETLEELMKLSPEELLLRWANFHL 281
           G   L LGL+W II      DI +             E ++     S ++ LL W    +
Sbjct: 670 GSSRLTLGLIWTIILRFQIQDIMI-------------EEVDNSETKSAKDALLLWC--QM 536

Query: 282 ENSGWQKIN--NFSADIKDSKAYFHLLNQIAPKGQKEGEPRIDINMSGFNETDDLKRAES 339
           + +G+  +N  NF+   +D  A+  ++++  P                  + D L ++ +
Sbjct: 535 KTAGYPNVNVRNFTTSWRDGLAFNAIIHKHRP---------------DLVQYDRLHKSSA 401

Query: 340 M--LQQA-----DKLGCRQFVTPADVVSGNP--KLNLAFVANLFNKYPAL 380
           +  LQ A     DKLG    + P DV    P  K  + +V   ++ +  +
Sbjct: 400 IQNLQNAFTVAEDKLGLTALLEPEDVNVEYPDEKSIITYVVTYYHYFSKM 251

 Score = 35.0 bits (79), Expect = 0.090,   Method: Compositional matrix adjust.
 Identities = 34/153 (22%), Positives = 74/153 (48%), Gaps = 5/153 (3%)
 Frame = -2

Query: 460 LENCNYAVELGKNPAKFSLVGIGGQDLNDGNPTLTLAVVWQLMRRYTLN--VLEDLGEGQ 517
           LEN + A+    +  +  L  +G  D+ DG+  LTL ++W ++ R+ +   ++E++   +
Sbjct: 754 LENVDKALTF-LHEQRVHLENMGAHDIVDGSSRLTLGLIWTIILRFQIQDIMIEEVDNSE 578

Query: 518 -KANDDIIVNWVNRTLSEAGK-STSIQSFKDKTISSSLAVVDLIDAIQPGCINYDLVKSG 575
            K+  D ++ W    +  AG  + ++++F   +    LA   +I   +P  + YD +   
Sbjct: 577 TKSAKDALLLWCQ--MKTAGYPNVNVRNFT-TSWRDGLAFNAIIHKHRPDLVQYDRLHKS 407

Query: 576 NLTEDDKHNNAKYAVSMAR-RIGARVYALPEDL 607
           +  +     N + A ++A  ++G      PED+
Sbjct: 406 SAIQ-----NLQNAFTVAEDKLGLTALLEPEDV 323
>05237
          Length = 472

 Score = 43.5 bits (101), Expect = 3e-04,   Method: Composition-based stats.
 Identities = 29/86 (33%), Positives = 47/86 (54%)
 Frame = +3

Query: 12 DELDELKEAFAKVDLNSNGFICDYELHELFKEANMPLPGYKVREIIQKLMVDGDRNKDGK 71
          D  DEL+EAF   D + NGFI   EL  +       L   +V E+I++  +DG    DG+
Sbjct: 18 DTDDELREAFRVFDKDGNGFISASELRHVMTNLGEKLTDEEVDEMIREADIDG----DGQ 185

Query: 72 ISFNEFVYIFQEVKSSDIAKTFRKAI 97
          +++ EFV    ++ ++  +KTF + I
Sbjct: 186VNYEEFV----KMMTTK*SKTFLQTI 251
>19147
          Length = 474

 Score = 39.7 bits (91), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 24/92 (26%), Positives = 48/92 (52%)
 Frame = +1

Query: 478 LVGIGGQDLNDGNPTLTLAVVWQLMRRYTLNVLEDLGEGQKANDDIIVNWVNRTLSEAGK 537
           LV IG +++ DGN  +TL ++W ++ R+    ++D+   +    + ++ W  R  +   K
Sbjct: 73  LVSIGAEEIVDGNVKMTLGMIWTIILRFA---IQDITVEELTAKEGLLLWCQRK-TAPYK 240

Query: 538 STSIQSFKDKTISSSLAVVDLIDAIQPGCINY 569
           + ++Q+F   +    LA   LI   +P  I+Y
Sbjct: 241 NVNVQNFH-LSFKDGLAFCALIHRHRPELIDY 333

 Score = 34.7 bits (78), Expect = 0.11,   Method: Compositional matrix adjust.
 Identities = 29/105 (27%), Positives = 45/105 (42%)
 Frame = +1

Query: 208 GCHVVNIGAEDLRAGKPHLVLGLLWQIIKIGLFADIELSRNEALAALLRDGETLEELMKL 267
           G  +V+IGAE++  G   + LG++W II      DI                T+EE   L
Sbjct: 64  GVKLVSIGAEEIVDGNVKMTLGMIWTIILRFAIQDI----------------TVEE---L 186

Query: 268 SPEELLLRWANFHLENSGWQKINNFSADIKDSKAYFHLLNQIAPK 312
           + +E LL W            + NF    KD  A+  L+++  P+
Sbjct: 187 TAKEGLLLWCQRKTAPYKNVNVQNFHLSFKDGLAFCALIHRHRPE 321
>14366
          Length = 499

 Score = 38.1 bits (87), Expect = 0.012,   Method: Compositional matrix adjust.
 Identities = 22/68 (32%), Positives = 35/68 (51%)
 Frame = -3

Query: 15  DELKEAFAKVDLNSNGFICDYELHELFKEANMPLPGYKVREIIQKLMVDGDRNKDGKISF 74
           D L+EAF   D   NG I   EL  +       L   +V E+I++  + GD    G++S+
Sbjct: 251 DNLREAFRIFDKEGNGMINAAELRHVLTHLGEKLSDEEVDEMIREADISGD----GQVSY 84

Query: 75  NEFVYIFQ 82
           N+FV + +
Sbjct: 83  NDFVKVME 60
>14594
          Length = 1014

 Score = 37.0 bits (84), Expect = 0.024,   Method: Compositional matrix adjust.
 Identities = 25/77 (32%), Positives = 39/77 (50%)
 Frame = +3

Query: 4   MATTQISKDELDELKEAFAKVDLNSNGFICDYELHELFKEANMPLPGYKVREIIQKLMVD 63
           MA      D  +EL+EAF   D + NG+I   EL  +       L   +V E+I++  +D
Sbjct: 627 MARKMKDTDCEEELREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIKEADLD 806

Query: 64  GDRNKDGKISFNEFVYI 80
           G    DG +++ EFV +
Sbjct: 807 G----DGMVNYEEFVTM 845
>29446
          Length = 1445

 Score = 36.2 bits (82), Expect = 0.042,   Method: Compositional matrix adjust.
 Identities = 33/135 (24%), Positives = 56/135 (41%), Gaps = 8/135 (5%)
 Frame = +3

Query: 403  FRNWMNS--LGVNPHVNHLYADLQDALVILQLYERIKVPVDWSKVNKPPYPKLGANMKKL 460
            F  W N     VN  +  L +D  D L ++ L E +     +  VNK P        +KL
Sbjct: 1014 FTRWANEHLRTVNKAIADLESDFSDGLRLVALIE-VLSGKKFKHVNKRP----NFRTQKL 1178

Query: 461  ENCNYAVELGKNPAKFSLVGIGGQDLNDGNPTLTLAVVWQLMRRYTLNVLEDLG------ 514
            EN    ++  ++     +V I   D+ D    L L ++W L+  Y++++    G      
Sbjct: 1179 ENVTLTLKFLEDDEGIRIVNIDSTDIVDKKLKLILGLIWTLILHYSISMPMWEGEEPTPS 1358

Query: 515  EGQKANDDIIVNWVN 529
            EG       ++NW+ 
Sbjct: 1359 EGGPTPKQRLLNWIQ 1403

 Score = 33.1 bits (74), Expect = 0.32,   Method: Compositional matrix adjust.
 Identities = 30/112 (26%), Positives = 47/112 (41%), Gaps = 1/112 (0%)
 Frame = +3

Query: 125  EKYAFVNWINKALENDPDCRHVIPMNPNTDDLFKAVGDGIVLCKMINLSVPDTIDERAIN 184
            +K  F  W N+         H+  +N    DL     DG+ L  +I +        + +N
Sbjct: 1002 QKNTFTRWANE---------HLRTVNKAIADLESDFSDGLRLVALIEVLSGKKF--KHVN 1148

Query: 185  KKKLTPFIIQENLNLALNS-ASAIGCHVVNIGAEDLRAGKPHLVLGLLWQII 235
            K+        EN+ L L       G  +VNI + D+   K  L+LGL+W +I
Sbjct: 1149 KRPNFRTQKLENVTLTLKFLEDDEGIRIVNIDSTDIVDKKLKLILGLIWTLI 1304
>17613
          Length = 1108

 Score = 34.7 bits (78), Expect = 0.11,   Method: Compositional matrix adjust.
 Identities = 25/91 (27%), Positives = 45/91 (49%)
 Frame = +2

Query: 203 SASAIGCHVVNIGAEDLRAGKPHLVLGLLWQIIKIGLFADIELSRNEALAALLRDGETLE 262
           ++++ G  +V+IGAE++  G   + LG++W II      DI +   E L A  ++G  L 
Sbjct: 47  TSTSKGVKLVSIGAEEIVDGNVKMTLGMIWTIILRFAIQDITV---EELTA--KEGLLLW 211

Query: 263 ELMKLSPEELLLRWANFHLENSGWQKINNFS 293
              K  P ++L    +  +   GW  +  F+
Sbjct: 212 CQRKQHPTKMLTSRTSISVLRMGWHSVPLFT 304

 Score = 32.0 bits (71), Expect = 0.75,   Method: Compositional matrix adjust.
 Identities = 11/31 (35%), Positives = 21/31 (67%)
 Frame = +2

Query: 478 LVGIGGQDLNDGNPTLTLAVVWQLMRRYTLN 508
           LV IG +++ DGN  +TL ++W ++ R+ + 
Sbjct: 71  LVSIGAEEIVDGNVKMTLGMIWTIILRFAIQ 163
>17504
          Length = 828

 Score = 33.1 bits (74), Expect = 0.34,   Method: Compositional matrix adjust.
 Identities = 16/39 (41%), Positives = 23/39 (58%), Gaps = 1/39 (2%)
 Frame = -1

Query: 25  DLNSNGFI-CDYELHELFKEANMPLPGYKVREIIQKLMV 62
            LNS  FI  +Y +  + K +N P PG + REI Q L++
Sbjct: 321 SLNSCKFILINYSITRMKKASNTPFPGMRPREIFQGLLI 205
>15966
          Length = 362

 Score = 32.7 bits (73), Expect = 0.48,   Method: Composition-based stats.
 Identities = 20/65 (30%), Positives = 30/65 (46%)
 Frame = +2

Query: 14  LDELKEAFAKVDLNSNGFICDYELHELFKEANMPLPGYKVREIIQKLMVDGDRNKDGKIS 73
           + +L E F   D + +G++   EL  L  E+        V  I++      D+N D KI 
Sbjct: 131 VQKLAELFKAKDKSGDGYLDRDELKALLDESGQKFTADDVSAILKS----ADKNNDNKIC 298

Query: 74  FNEFV 78
           F EFV
Sbjct: 299 FEEFV 313
>01019
          Length = 1705

 Score = 32.0 bits (71), Expect = 0.75,   Method: Compositional matrix adjust.
 Identities = 18/56 (32%), Positives = 30/56 (53%)
 Frame = +1

Query: 25  DLNSNGFICDYELHELFKEANMPLPGYKVREIIQKLMVDGDRNKDGKISFNEFVYI 80
           D + NGFI   EL  +       L   +V E+I++  +DG    DG++++ EFV +
Sbjct: 49  DKDGNGFISAAELRHVMTNLGEKLTDEEVDEMIREADIDG----DGQVNYEEFVTM 204
>07198
          Length = 1675

 Score = 31.6 bits (70), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 19/65 (29%), Positives = 31/65 (47%)
 Frame = -3

Query: 14  LDELKEAFAKVDLNSNGFICDYELHELFKEANMPLPGYKVREIIQKLMVDGDRNKDGKIS 73
           +DE ++ F   D N +G +   E    F      +P    +  +++ M   D+NKDG IS
Sbjct: 485 VDEDRKVFDAADANKDGSLNSKEYFAFF------MPNSFPQLELERFMRQSDKNKDGTIS 324

Query: 74  FNEFV 78
             EF+
Sbjct: 323 MEEFM 309
>26896
          Length = 1498

 Score = 30.8 bits (68), Expect = 1.7,   Method: Compositional matrix adjust.
 Identities = 18/57 (31%), Positives = 25/57 (43%), Gaps = 3/57 (5%)
 Frame = +2

Query: 272 LLLRWANFHLENSGWQKI---NNFSADIKDSKAYFHLLNQIAPKGQKEGEPRIDINM 325
           L+ +WA+ HL   GW KI   N FS      K YF +       G++E      + M
Sbjct: 404 LIPKWASNHLRYVGW*KIRRKNTFSLSFTSFKVYFEICG*TQLIGRQENSQVFPVXM 574
>01773
          Length = 1950

 Score = 30.0 bits (66), Expect = 2.9,   Method: Compositional matrix adjust.
 Identities = 20/63 (31%), Positives = 29/63 (46%)
 Frame = +1

Query: 16  ELKEAFAKVDLNSNGFICDYELHELFKEANMPLPGYKVREIIQKLMVDGDRNKDGKISFN 75
           +L E F   D + +G++   EL  L  E+        V  I++      D+N D KI F 
Sbjct: 370 KLAELFKAKDKSGDGYLDRDELKALLDESGQKFTADDVSAILKS----ADKNNDNKICFE 537

Query: 76  EFV 78
           EFV
Sbjct: 538 EFV 546
>00115
          Length = 2896

 Score = 29.6 bits (65), Expect = 3.9,   Method: Compositional matrix adjust.
 Identities = 11/35 (31%), Positives = 23/35 (65%)
 Frame = -2

Query: 117  TQHSYSEEEKYAFVNWINKALENDPDCRHVIPMNP 151
            + H +  E +++FVN +NK ++N+ +C    P++P
Sbjct: 2253 STHEHINEHRFSFVNCVNKCIDNNENC----PISP 2161
>07153
          Length = 1469

 Score = 28.9 bits (63), Expect = 5.9,   Method: Compositional matrix adjust.
 Identities = 14/43 (32%), Positives = 19/43 (44%)
 Frame = -3

Query: 422 DLQDALVILQLYERIKVPVDWSKVNKPPYPKLGANMKKLENCN 464
           D    +++     R     D SKVNK PYP    N+ +   CN
Sbjct: 495 DAASDVILFLCTSRYF*TCDGSKVNKLPYPSFYINIDRFSFCN 367
>26610
          Length = 455

 Score = 28.9 bits (63), Expect = 6.3,   Method: Composition-based stats.
 Identities = 17/66 (25%), Positives = 31/66 (46%)
 Frame = +3

Query: 16  ELKEAFAKVDLNSNGFICDYELHELFKEANMPLPGYKVREIIQKLMVDGDRNKDGKISFN 75
           +L EAF  +D   +GF+   EL  L       +   +   ++++L VD     +G++   
Sbjct: 261 QLDEAFNTIDKEGSGFVMATELRHLLTHMGDRITDEEFNALLEELEVD----SNGRVRRK 428

Query: 76  EFVYIF 81
           EFV + 
Sbjct: 429 EFVQLL 446
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|54020676|ref|NP_001005509.1| eukaryotic translation
initiation factor 2A [Mus musculus]
         (581 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

06563                                                                 528   e-150
11361                                                                  35   0.10 
01070                                                                  32   0.58 
34005                                                                  29   4.4  
11117                                                                  29   5.4  
>06563
          Length = 2303

 Score =  528 bits (1361), Expect = e-150,   Method: Compositional matrix adjust.
 Identities = 269/576 (46%), Positives = 348/576 (60%), Gaps = 3/576 (0%)
 Frame = -2

Query: 8    LTVRGSEGLYMVNGPPHFTESTVLPRESGRNCKVYTFSKDGTLFAWSNGEKVNIINVANK 67
            L +RGSEG+++VNG P    +     + G+ CK   +S DG L AW+  + V ++ V+  
Sbjct: 2296 LALRGSEGIWIVNGAPGHDPTPKHRCDQGKTCKAMAYSADGRLLAWATADCVYVMXVSTY 2117

Query: 68   GLLHSFDLPKAVCLEFSPNNTVLATWQPYTTSKDGTAGTPNLQLYDMKTGACLKSFIQKK 127
             +       +   L FSP  +VLATW P+   +DG  G PN+ ++D  +G  LK+F+QKK
Sbjct: 2116 TVKQQLQQTRVAELMFSPRGSVLATWGPFYMDRDGKGGEPNMVIWDXASGNVLKTFVQKK 1937

Query: 128  MQNWCPSWSDDEIICARXXXXXXXXXXXXXXXTIANKLHLQKVNDFNLSPGTQPYKVAVY 187
               W  +WS DE IC R               T+A +LHLQKV DF+L+P + PY ++ Y
Sbjct: 1936 QIGWELAWSVDEAICCRTANSEVHFYENNNFDTVAQRLHLQKVVDFSLAPASAPYVISAY 1757

Query: 188  VPGSKGAPSFVRLYQYPNFAGPQAALANKSFFKADKVTMLWNKKATAVLVIASTEVDKTG 247
            V G KG PSFVR+Y+YP+F G  AA+ANKSF+KAD+V   WNK  T ++++ STE   + 
Sbjct: 1756 VAGVKGQPSFVRVYRYPHFDGQSAAIANKSFYKADRVNTFWNKTGTGLVILTSTE--SSD 1583

Query: 248  ASYYGEQTLHYIATNGESAVVQLPKNGPIYDVVWNSSSTEFCAVYGFMPAKATVFNLKCD 307
            +SYYGEQ LHYI+T+GES +V L K GP+Y V+W+  + EFC VYGFMPAK T+FNLKC+
Sbjct: 1582 SSYYGEQGLHYISTSGESCLVPLEKKGPVYSVMWSPKNNEFCVVYGFMPAKVTLFNLKCE 1403

Query: 308  PVFDFGTGPRNAAFYSPHGHILVLAGFGNLRGQMEVWDVKNYKLISKPVASDSTYFAWCP 367
            PVFDFGTGPRN  FY+P G+IL LAGFGNL G ME WD+K  K ISK  A+D+T FAW P
Sbjct: 1402 PVFDFGTGPRNHCFYNPQGNILCLAGFGNLAGHMEFWDLKQKKEISKFKAADTTNFAWSP 1223

Query: 368  DGEHILTATCAPRLRVNNGYKIWHYTGSLLHKYDVPSNGELWQVSWQPFLDGIFPAKTIK 427
            DGEH LTAT +PRLRV+NGY++WHYTGSLL     P    L+   WQP  +G F  K ++
Sbjct: 1222 DGEHFLTATVSPRLRVSNGYRLWHYTGSLLSSVSTPEGESLFDAIWQPAPEGTFKEKAVR 1043

Query: 428  YQAVPSEVPSEEPKVATAYRPPALRNKPVTNS-KLHEEEPPQNMK-PHPGSDKPLSKTAL 485
            Y+     + + E K   AYRPP  R    T S KLHE EP  N+K     +DKP SK   
Sbjct: 1042 YKPAEPGLDTVENKKTXAYRPPQARGANYTPSVKLHEYEPASNVKQAQAAADKPASKNKK 863

Query: 486  KNXXXXXXXXX-XXXXXXSDAAPTPVPQSAPRNTVTQSASGDPEVDXXXXXXXXXXXAIE 544
            K                 S  A      +         ++GDPE D            IE
Sbjct: 862  KRDARKAKATEGEESAVTSGPATPAAVTAPAPAATPAVSTGDPEKDKKIRNLRKKLQQIE 683

Query: 545  QLKEQAAAGKQLEKNQLEKIQKETALLQELEDLELG 580
            +LK+Q   GKQLE NQLEK++ E  LLQELEDLE+G
Sbjct: 682  KLKDQQKGGKQLEMNQLEKLKSEAGLLQELEDLEIG 575
>11361
          Length = 665

 Score = 34.7 bits (78), Expect = 0.10,   Method: Compositional matrix adjust.
 Identities = 19/48 (39%), Positives = 27/48 (56%), Gaps = 2/48 (4%)
 Frame = -1

Query: 98  TSKDGTAGTPNLQLYDMKTGACLKSFIQKKMQNWCPSWSDDEI--ICA 143
           T+K G   T N+   D+KT +C ++ I     NW P W +DEI  IC+
Sbjct: 422 TTKRGCTCTCNVXTMDLKTRSC-QTQISSAAINWLPFWKNDEICXICS 282
>01070
          Length = 1597

 Score = 32.3 bits (72), Expect = 0.58,   Method: Compositional matrix adjust.
 Identities = 14/40 (35%), Positives = 20/40 (50%), Gaps = 9/40 (22%)
 Frame = +2

Query: 364 AWCPDGEHILTATCAPRL---------RVNNGYKIWHYTG 394
           +WC     +L  +C PRL         +VNN Y +W+Y G
Sbjct: 149 SWCRFDIVLLDVSCLPRLSLASAVQAFKVNNNYVLWYYLG 268
>34005
          Length = 456

 Score = 29.3 bits (64), Expect = 4.4,   Method: Compositional matrix adjust.
 Identities = 22/83 (26%), Positives = 36/83 (43%), Gaps = 3/83 (3%)
 Frame = +1

Query: 43  TFSKDGTLFAWSNGEKVNIINVANKGLLHSFDLPKAVCLEFSPNNTVLATWQPYTTSKDG 102
           ++S D T  A  +G   N +N+ +  L    D+P    L           W P+ T    
Sbjct: 133 SWSPDATFLA--SGSNDNSVNIWDSTL--GMDVPPLHTLTSHQAAVKAVAWCPWQTRMLA 300

Query: 103 TAGTPN---LQLYDMKTGACLKS 122
           T G  N   ++ ++  TGAC+K+
Sbjct: 301 TGGGTNDRHIRFWNTNTGACVKA 369
>11117
          Length = 573

 Score = 28.9 bits (63), Expect = 5.4,   Method: Composition-based stats.
 Identities = 15/46 (32%), Positives = 24/46 (52%)
 Frame = +2

Query: 382 RVNNGYKIWHYTGSLLHKYDVPSNGELWQVSWQPFLDGIFPAKTIK 427
           +V+N Y IW++ G+LL K  +       Q+ W+P    +   K IK
Sbjct: 17  KVDNAYWIWNFQGNLLVKQPME---RFCQLMWRPRAPSLLTDKQIK 145
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|114052442|ref|NP_057922.2| misshapen-like kinase 1
isoform 1 [Mus musculus]
         (1300 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

01431                                                                 526   e-149
27197                                                                 228   1e-59
06151                                                                 183   2e-52
18921                                                                 188   2e-47
13212                                                                 180   2e-45
19094                                                                 126   7e-43
12721                                                                 167   2e-41
14420                                                                 144   2e-34
00300                                                                 133   4e-31
13592                                                                 117   3e-26
37602                                                                  89   2e-22
06405                                                                  84   3e-16
01756                                                                  84   3e-16
01718                                                                  84   4e-16
01707                                                                  84   4e-16
14126                                                                  83   7e-16
01060                                                                  81   3e-15
09606                                                                  79   9e-15
21079                                                                  79   2e-14
28638                                                                  64   2e-14
04852                                                                  77   5e-14
03240                                                                  76   9e-14
12786                                                                  74   3e-13
30755                                                                  71   2e-12
00392                                                                  71   3e-12
18484                                                                  70   6e-12
31885                                                                  70   6e-12
21808                                                                  69   1e-11
00715                                                                  68   3e-11
29581                                                                  67   4e-11
15910                                                                  67   4e-11
01392                                                                  67   5e-11
14116                                                                  66   7e-11
19301                                                                  66   8e-11
26560                                                                  65   1e-10
11780                                                                  63   9e-10
07940                                                                  62   2e-09
04591                                                                  61   3e-09
17975                                                                  61   3e-09
21433                                                                  60   4e-09
19761                                                                  60   4e-09
01966                                                                  60   4e-09
27405                                                                  60   7e-09
17253                                                                  59   1e-08
09007                                                                  59   2e-08
13066                                                                  58   2e-08
26711                                                                  57   6e-08
16708                                                                  57   6e-08
21210                                                                  57   6e-08
07291                                                                  55   2e-07
03508                                                                  54   3e-07
04138                                                                  52   2e-06
07836                                                                  51   3e-06
14477                                                                  50   7e-06
17300                                                                  49   1e-05
27546                                                                  47   5e-05
12672                                                                  45   1e-04
11404                                                                  41   0.002
25019                                                                  41   0.003
07833                                                                  41   0.004
11185                                                                  41   0.004
31489                                                                  40   0.005
18996                                                                  40   0.006
28157                                                                  40   0.007
20640                                                                  39   0.012
37063                                                                  39   0.016
24241                                                                  38   0.021
18663                                                                  37   0.043
32359                                                                  37   0.058
36481                                                                  37   0.059
02638                                                                  37   0.064
01106                                                                  35   0.16 
00486                                                                  35   0.16 
32691                                                                  35   0.28 
28865                                                                  34   0.34 
18481                                                                  34   0.36 
17516                                                                  34   0.47 
26156                                                                  33   0.62 
15741                                                                  33   0.64 
29590                                                                  33   0.76 
21800                                                                  33   0.81 
22005                                                                  33   0.82 
32000                                                                  32   1.8  
26009                                                                  32   2.4  
21727                                                                  30   4.7  
>01431
          Length = 1309

 Score =  526 bits (1356), Expect = e-149,   Method: Compositional matrix adjust.
 Identities = 238/325 (73%), Positives = 283/325 (87%), Gaps = 3/325 (0%)
 Frame = +2

Query: 979  IRKYKKRFNSEILCAALWGVNLLVGTENGLMLLDRSGQGKVYGLIGRRRFQQMDVLEGLN 1038
            IRKYKKRFNSEILCAALWGVNLL+GTENGLMLLDRSGQGKVY LI RRRFQQM+VLEG N
Sbjct: 2    IRKYKKRFNSEILCAALWGVNLLIGTENGLMLLDRSGQGKVYQLISRRRFQQMEVLEGQN 181

Query: 1039 LLITISGKRNKLRVYYLSWLRNKILHND---PEVEKKQGWTTVGDMEGCGHYRVVKYERI 1095
            +L+TISGK+N++RVYYLSWL++KIL  D    +VE++ GW  VGD++G  H+++VKYERI
Sbjct: 182  ILVTISGKKNRVRVYYLSWLKSKILRTDGLSDQVERRNGWINVGDLQGAVHFKIVKYERI 361

Query: 1096 KFLVIALKNSVEVYAWAPKPYHKFMAFKSFADLPHRPLLVDLTVEEGQRLKVIYGSSAGF 1155
            KFLVIALK+S+E+YAWAPKPYHKFMAFK+F +L HRPLLVDLT+E+  RLKVIYGS+ GF
Sbjct: 362  KFLVIALKDSIEIYAWAPKPYHKFMAFKNFGELEHRPLLVDLTIEDQSRLKVIYGSAEGF 541

Query: 1156 HAVDVDSGNSYDIYIPVHIQSQITPHAIIFLPNTDGMEMLLCYEDEGVYVNTYGRIIKDV 1215
            HAVD+DS   YDIY+P H Q  I PH I+ LPN++GM++LLCY++EGVYVNT GR+ K++
Sbjct: 542  HAVDLDSAEVYDIYLPKHTQGAIIPHCIVALPNSNGMQLLLCYDNEGVYVNTAGRVSKNI 721

Query: 1216 VLQWGEMPTSVAYICSNQIMGWGEKAIEIRSVETGHLDGVFMHKRAQRLKFLCERNDKVF 1275
            VLQWGEMPTSVAYI + QIMGWG KAIEIRSVE+GHLDGVFMHK+AQRLKFLCERNDKVF
Sbjct: 722  VLQWGEMPTSVAYIGTGQIMGWGNKAIEIRSVESGHLDGVFMHKKAQRLKFLCERNDKVF 901

Query: 1276 FASVRSGGSSQVYFMTLNRNCIMNW 1300
            F+S +   S Q+YFMTLN+  + NW
Sbjct: 902  FSSAKGASSCQIYFMTLNKPGMANW 976
>27197
          Length = 450

 Score =  228 bits (581), Expect = 1e-59,   Method: Compositional matrix adjust.
 Identities = 104/139 (74%), Positives = 124/139 (89%)
 Frame = +1

Query: 975  ETPEIRKYKKRFNSEILCAALWGVNLLVGTENGLMLLDRSGQGKVYGLIGRRRFQQMDVL 1034
            +TPEIRKYKKRF S+ILCAALWGVNLL+GTENGLMLLDRSGQGKVY LI RRRFQQM+VL
Sbjct: 1    DTPEIRKYKKRFGSDILCAALWGVNLLIGTENGLMLLDRSGQGKVYTLISRRRFQQMEVL 180

Query: 1035 EGLNLLITISGKRNKLRVYYLSWLRNKILHNDPEVEKKQGWTTVGDMEGCGHYRVVKYER 1094
            EG N+L+TISGK+NK+RVYYLSWL+ KI  +D   +KK G+  VG++EGC H+++VKYER
Sbjct: 181  EGQNILVTISGKKNKIRVYYLSWLKTKIFKSDGS-DKKNGFVNVGELEGCVHFKIVKYER 357

Query: 1095 IKFLVIALKNSVEVYAWAP 1113
            IKFLVIAL +S+E+YAWAP
Sbjct: 358  IKFLVIALHDSIEIYAWAP 414
>06151
          Length = 503

 Score =  183 bits (464), Expect(2) = 2e-52,   Method: Composition-based stats.
 Identities = 92/189 (48%), Positives = 116/189 (61%), Gaps = 3/189 (1%)
 Frame = -1

Query: 1014 SGQGKVYGLIGRRRFQQMDVLEGLNLLITISGKRNKLRVYYLSWLRNKILHND---PEVE 1070
            SGQGKVY LI RRRFQQM+VLEG N+L+TISGK+N++RVYYLSWL++KIL  D    +VE
Sbjct: 446  SGQGKVYQLISRRRFQQMEVLEGQNILVTISGKKNRVRVYYLSWLKSKILRTDGLSDQVE 267

Query: 1071 KKQGWTTVGDMEGCGHYRVVKYERIKFLVIALKNSVEVYAWAPKPYHKFMAFKSFADLPH 1130
            ++ GW  VGD++                                          F     
Sbjct: 266  RRNGWINVGDLQ-----------------------------------------EFW*TGT 210

Query: 1131 RPLLVDLTVEEGQRLKVIYGSSAGFHAVDVDSGNSYDIYIPVHIQSQITPHAIIFLPNTD 1190
             PLLVDLT+E+  RLKVIYGS+ GFHAVD+DS   YDIY+P H Q  I PH I+ LPN++
Sbjct: 209  SPLLVDLTIEDQSRLKVIYGSAEGFHAVDLDSAEVYDIYLPKHTQGAIIPHCIVALPNSN 30

Query: 1191 GMEMLLCYE 1199
            GM++LLCY+
Sbjct: 29   GMQLLLCYD 3

 Score = 43.1 bits (100), Expect(2) = 2e-52,   Method: Composition-based stats.
 Identities = 17/24 (70%), Positives = 21/24 (87%)
 Frame = -2

Query: 995  LWGVNLLVGTENGLMLLDRSGQGK 1018
            +WGVNLL+GTENGLMLLDR  + +
Sbjct: 502  VWGVNLLIGTENGLMLLDRLARAR 431
>18921
          Length = 697

 Score =  188 bits (477), Expect = 2e-47,   Method: Compositional matrix adjust.
 Identities = 106/241 (43%), Positives = 147/241 (60%), Gaps = 3/241 (1%)
 Frame = +2

Query: 16  SALRDPAGIFELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTXXXXXXIKQEINMLKK 75
           S  R P  +F+++  +G G+YG V+K  H +TGQ+ AIK + V       IK EI+++++
Sbjct: 8   SLARPPEDVFDILGKLGEGSYGSVFKSLHKETGQVLAIKQVPVDTDLQEIIK-EISIMQQ 184

Query: 76  YSHHRNIATYYGAFIKKSPPGNDDQLWLVMEFCGAGSVTDLVKNTKGNALKEDCIAYICR 135
               + I  YYG++ K +       LW+VME+CGAGSV+D+++  +   L E  IA I  
Sbjct: 185 -CDSKYIVKYYGSYFKNT------DLWIVMEYCGAGSVSDIMR-LRNKTLVEREIATILY 340

Query: 136 EILRGLAHLHAHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWM 195
             L+GL +LH+ + IHRDIK  N+LL      KL DFGV+ QL  T+ +RNT IGTPYWM
Sbjct: 341 YTLKGLXYLHSRRKIHRDIKAGNILLNNEGHAKLADFGVAGQLTDTMAKRNTVIGTPYWM 520

Query: 196 APEVIACDENPDATYDYRSDIWSLGITAIEMAEGAPPLCDMHPM---RALFLIPRNPPPR 252
           APEVI      +  YD  +DIWSLGITA+EMAEG PP+ +   +    + F  P N PP 
Sbjct: 521 APEVIQ-----EIGYDCVADIWSLGITALEMAEGKPPVMETSIL*GQSS*F--PTNAPPP 679

Query: 253 L 253
           L
Sbjct: 680 L 682
>13212
          Length = 1067

 Score =  180 bits (456), Expect(2) = 2e-45,   Method: Composition-based stats.
 Identities = 90/167 (53%), Positives = 114/167 (68%), Gaps = 1/167 (0%)
 Frame = -1

Query: 125 LKEDCIAYICREILRGLAHLHAHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGR 184
           + E  I Y+C E+   L  LH H VIHRDIK  NVLLT + EVKL DFGVSA+  +T  +
Sbjct: 989 MTEAQICYVCHEMCMALDFLHRHHVIHRDIKAGNVLLTIDGEVKLADFGVSAKNTQTQQK 810

Query: 185 RNTFIGTPYWMAPEVIACDENPDATYDYRSDIWSLGITAIEMAEGAPPLCDMHPMRALFL 244
           R+TFIGTPYWMAPEV+ C+   D  YD+++DIWSLG+T IE A+  PP  +MHPMR L  
Sbjct: 809 RDTFIGTPYWMAPEVVLCETLKDTPYDFKADIWSLGVTLIEFAQIEPPNKEMHPMRVLIK 630

Query: 245 IPRNPPPRL-KSKKWSKKFTDFIDTCLIKTYLSRPPTEQLLKFPFIR 290
           I ++ PP L K KKW+K F DFI  CL+K    RP   +LL+ PF++
Sbjct: 629 IHKSDPPTLEKPKKWTKLFKDFIAKCLVKDPNLRPTAAELLEHPFMK 489

 Score = 22.7 bits (47), Expect(2) = 2e-45,   Method: Composition-based stats.
 Identities = 6/10 (60%), Positives = 8/10 (80%)
 Frame = -2

Query: 101  LWLVMEFCGA 110
            LW+ +EFCG 
Sbjct: 1057 LWMFLEFCGG 1028
>19094
          Length = 898

 Score =  126 bits (317), Expect(2) = 7e-43,   Method: Composition-based stats.
 Identities = 65/121 (53%), Positives = 81/121 (66%)
 Frame = +1

Query: 109 GAGSVTDLVKNTKGNALKEDCIAYICREILRGLAHLHAHKVIHRDIKGQNVLLTENAEVK 168
           GAGSV+D+++  +   L E  IA I    L+GL +LH+ + IHRDIK  N+LL      K
Sbjct: 4   GAGSVSDIMR-LRNKTLVEREIATILYYTLKGL*YLHSRRKIHRDIKAGNILLNNEGHAK 180

Query: 169 LVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDATYDYRSDIWSLGITAIEMAE 228
           L DFGV+ QL  T+ +RNT IGTPYWMAPEVI      +  YD  +DIWSLGITA+EMAE
Sbjct: 181 LADFGVAGQLTDTMAKRNTVIGTPYWMAPEVIQ-----EIGYDCVADIWSLGITALEMAE 345

Query: 229 G 229
           G
Sbjct: 346 G 348

 Score = 67.4 bits (163), Expect(2) = 7e-43,   Method: Compositional matrix adjust.
 Identities = 29/63 (46%), Positives = 39/63 (61%), Gaps = 1/63 (1%)
 Frame = +3

Query: 229 GAPPLCDMHPMRALFLIPRNPPPRLKS-KKWSKKFTDFIDTCLIKTYLSRPPTEQLLKFP 287
           G PP  D+HPMRA+F+IP  PPP  +   KWS +F DF+  CL+K   +R     LL+  
Sbjct: 345 GKPPYGDIHPMRAIFMIPTKPPPSFRQPDKWSTEFIDFVSKCLVKNPENRATAVDLLQHD 524

Query: 288 FIR 290
           FI+
Sbjct: 525 FIK 533
>12721
          Length = 821

 Score =  167 bits (424), Expect = 2e-41,   Method: Compositional matrix adjust.
 Identities = 96/255 (37%), Positives = 145/255 (56%), Gaps = 2/255 (0%)
 Frame = +1

Query: 20  DPAGIFELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTXXXXXXIK-QEINMLKKYSH 78
           DP    +    +G G+ G V      + G+  A+K MD+       +   E+ +++ Y H
Sbjct: 79  DPRTFLDDFMKIGEGSTGIVCIATS-RDGRQMAVKKMDLRKQQRRELLFNEVVVMRDY-H 252

Query: 79  HRNIATYYGAFIKKSPPGNDDQLWLVMEFCGAGSVTDLVKNTKGNALKEDCIAYICREIL 138
           H NI   Y +++       +D+LW+VMEF   G++TD+V N   N + E  IA +CR  L
Sbjct: 253 HPNIVEMYNSYLV------NDELWVVMEFMEGGALTDIVTN---NRMDEVQIATVCRACL 405

Query: 139 RGLAHLHAHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPE 198
           + LA LHA+ VIHRDIK  ++LL+ + +VKL DFG  AQ+ + + +R + +GTPYWMAPE
Sbjct: 406 KALAFLHANGVIHRDIKSDSILLSHDGKVKLXDFGFCAQVTQDLQKRKSLVGTPYWMAPE 585

Query: 199 VIACDENPDATYDYRSDIWSLGITAIEMAEGAPPLCDMHPMRALFLIPRNPPPRLK-SKK 257
           VI+        Y    DIWSLGI  +EM +  PP  +  P++A+  I   PPP+L+ + K
Sbjct: 586 VIS-----RLPYGPEVDIWSLGIMVMEMIDAEPPFFNEPPLQAMRRIRDMPPPKLRNTHK 750

Query: 258 WSKKFTDFIDTCLIK 272
            S +   FID  L++
Sbjct: 751 ISPRLQGFIDRMLVR 795
>14420
          Length = 528

 Score =  144 bits (364), Expect = 2e-34,   Method: Compositional matrix adjust.
 Identities = 74/171 (43%), Positives = 102/171 (59%)
 Frame = +2

Query: 72  MLKKYSHHRNIATYYGAFIKKSPPGNDDQLWLVMEFCGAGSVTDLVKNTKGNALKEDCIA 131
           ++ + + + NI  Y  +++        ++LW+VMEF   GS+TD+V  T    + E  IA
Sbjct: 56  LVMRENQNPNIVNYLDSYLV------GEELWVVMEFLAGGSLTDVVTET---CMDEGQIA 208

Query: 132 YICREILRGLAHLHAHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGT 191
            +CRE L+ L  LH ++VIHRDIK  N+LL  +  VKL DFG  AQL     +R+T +GT
Sbjct: 209 AVCRECLQALEFLHENQVIHRDIKSDNILLGMDGSVKLTDFGFCAQLSPEQSKRSTMVGT 388

Query: 192 PYWMAPEVIACDENPDATYDYRSDIWSLGITAIEMAEGAPPLCDMHPMRAL 242
           PYWMAPEV+         Y    DIWSLG+  IEM EG PP  + +P+RAL
Sbjct: 389 PYWMAPEVVT-----RKQYGPTVDIWSLGVMCIEMIEGEPPYLNENPLRAL 526
>00300
          Length = 2318

 Score =  133 bits (335), Expect = 4e-31,   Method: Compositional matrix adjust.
 Identities = 83/266 (31%), Positives = 128/266 (48%), Gaps = 6/266 (2%)
 Frame = -1

Query: 31   VGNGTYGQVYKGRHVKTGQLAAIKVMDVTXXXXXXIKQEINMLKKYS--HHRNIATYYGA 88
            +G G +G+VY   ++ TG+L A+K M         +++  + +K +    H N+  YYG 
Sbjct: 1634 IGEGQFGKVYTAVNMSTGELMALKEMKFQPNDLQQLREMCDEIKIFEGIQHENLVKYYGV 1455

Query: 89   FIKKSPPGNDDQLWLVMEFCGAGSVTDLVKNTKGNALKEDCIAYICREILRGLAHLHAHK 148
             + K      D++ + ME+C  G++ +  K      L E  I    REI+  + HLH + 
Sbjct: 1454 EVHK------DEMLMFMEYCDTGTIEEAAKM----GLPEYLIRRYTREIVLAVNHLHENS 1305

Query: 149  VIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTV---GRRNTFIGTPYWMAPEVIACDEN 205
            ++HRDIKG N+ LT N  VKL DFG S +L       G  +  +GT  +MAPEV    +N
Sbjct: 1304 IVHRDIKGANIFLTSNGHVKLGDFGCSVKLKSHTTMPGEFHNLVGTTAYMAPEVFT--QN 1131

Query: 206  PDATYDYRSDIWSLGITAIEMAEGAPPLCDM-HPMRALFLIPRNPPPRLKSKKWSKKFTD 264
                Y   +DIWSLG   IEMA G  P  D+ +  + ++ +     P +     S +   
Sbjct: 1130 DQGGYGRAADIWSLGCVVIEMATGKRPWHDLDNNYQIMYKVGIGHKPAVPD-SLSVEGKH 954

Query: 265  FIDTCLIKTYLSRPPTEQLLKFPFIR 290
            F+D  +      R    QLL   F +
Sbjct: 953  FLDLIMCHDPAQRALASQLLDHTFTK 876
>13592
          Length = 980

 Score =  117 bits (293), Expect = 3e-26,   Method: Compositional matrix adjust.
 Identities = 86/285 (30%), Positives = 140/285 (49%), Gaps = 12/285 (4%)
 Frame = +2

Query: 31  VGNGTYGQVYKGRHVKTGQLAAIKVMDVTXXXXXXIK---QEINMLKKYSHHRNIATYYG 87
           +G G +G+VY   +  TG+L A+K + +       +K   +E+ +L+   H +N+  YYG
Sbjct: 8   IGQGRFGKVYTAVNNNTGELMAMKEIAIQPGETRALKNVAEELKILEGIKH-KNLVRYYG 184

Query: 88  AFIKKSPPGNDDQLWLVMEFCGAGSVTDLVKNTKGNALKEDCIAYICREILRGLAHLHAH 147
             + +      ++L + ME C  G++  LV+ T G  L E        ++L G+A LH H
Sbjct: 185 IEVHR------EELLIFMELCSEGTLESLVELTGG--LPEALSRRFTAQLLSGVAELHKH 340

Query: 148 KVIHRDIKGQNVLLTENA-EVKLVDFG--VSAQLDRTV-GRRNTFIGTPYWMAPEVIACD 203
            ++HRDIK  N+ L + +  +KL DFG  V  Q   TV G    ++GT  +MAPEV    
Sbjct: 341 GIVHRDIKTANIFLVDGSNSLKLGDFGSAVKIQAHTTVPGELQGYVGTQAYMAPEVFT-K 517

Query: 204 ENPDATYDYRSDIWSLGITAIEMAEGAPPLCDMHP-MRALFLIPRNPPPRLKSKKWSKKF 262
            N D  +   +DIWS+G   +EMA G  P        + +F +     P+   +  S++ 
Sbjct: 518 TNSDG-HGRLADIWSVGCVVVEMASGKRPWAQFDSNFQIMFKVGMGEKPQ-APESLSQEG 691

Query: 263 TDFIDTCLIKTYLSRPPTEQLLKFPFIR----DQPTERQVRIQLK 303
            DFID CL      R    +LL+  F +    ++    Q+  Q++
Sbjct: 692 HDFIDHCLQHDPKQRLSAIELLEQNFCKSGRDEECNSEQLHAQMR 826
>37602
          Length = 804

 Score = 89.4 bits (220), Expect(3) = 2e-22,   Method: Compositional matrix adjust.
 Identities = 50/117 (42%), Positives = 66/117 (56%), Gaps = 5/117 (4%)
 Frame = -1

Query: 81  NIATYYGAFIKKSPPGNDDQLWLVMEFCGAGSVTDLVKNTKGNALKEDCIAYICREILRG 140
           NI T+ G F         ++LW+ ME+CG GS+ D+   T    L E  IA++CRE L+G
Sbjct: 345 NIQTFVGYF---DSYLRREKLWIAMEYCGGGSMQDIYHVT--GPLTEPQIAFVCRETLKG 181

Query: 141 LAHLHAHKVIHRDIKGQNVLLTENAEVKLVDF-----GVSAQLDRTVGRRNTFIGTP 192
           L +LH    +HRDIKG N+LLTE  +VKL DF       S  + + V   N FIG P
Sbjct: 180 LHYLHRRGKMHRDIKGANILLTEEGDVKLADFWRVSSNHSHNVQKKVFHWNAFIGWP 10

 Score = 34.3 bits (77), Expect(3) = 2e-22,   Method: Composition-based stats.
 Identities = 14/25 (56%), Positives = 19/25 (76%)
 Frame = -2

Query: 19  RDPAGIFELVEVVGNGTYGQVYKGR 43
           R+P   FEL++ VG+GTYG VYK +
Sbjct: 521 RNPLDDFELIQRVGSGTYGDVYKAK 447

 Score = 21.9 bits (45), Expect(3) = 2e-22,   Method: Composition-based stats.
 Identities = 7/7 (100%), Positives = 7/7 (100%)
 Frame = -3

Query: 193 YWMAPEV 199
           YWMAPEV
Sbjct: 22  YWMAPEV 2

 Score = 46.2 bits (108), Expect(2) = 1e-05,   Method: Composition-based stats.
 Identities = 18/26 (69%), Positives = 22/26 (84%)
 Frame = -1

Query: 171 DFGVSAQLDRTVGRRNTFIGTPYWMA 196
           DFGVSAQ+  T+ +R +FIGTPYWMA
Sbjct: 744 DFGVSAQITATMCKRKSFIGTPYWMA 667

 Score = 22.7 bits (47), Expect(2) = 1e-05,   Method: Composition-based stats.
 Identities = 9/13 (69%), Positives = 11/13 (84%)
 Frame = -2

Query: 158 NVLLTENAEVKLV 170
           N+LLTE  +VKLV
Sbjct: 803 NILLTEEGDVKLV 765

 Score = 32.7 bits (73), Expect = 0.90,   Method: Composition-based stats.
 Identities = 14/26 (53%), Positives = 18/26 (69%)
 Frame = -2

Query: 172 FGVSAQLDRTVGRRNTFIGTPYWMAP 197
           FGVSAQ+  T+ +R +FIGTP    P
Sbjct: 86  FGVSAQITATMCKRKSFIGTPLLDGP 9
>06405
          Length = 1965

 Score = 84.3 bits (207), Expect = 3e-16,   Method: Compositional matrix adjust.
 Identities = 52/201 (25%), Positives = 95/201 (47%), Gaps = 4/201 (1%)
 Frame = +1

Query: 31  VGNGTYGQVYKGRHVKTGQLAAIKVMDVTXXXXXXIKQEINMLKKYSHHRNIATYYGAFI 90
           +G G YG VY+    +  ++ A+K +           +E  ++K+  H  N+    G   
Sbjct: 283 LGGGQYGDVYEAMWKRYNKIVAVKTLKEDTMALNDFLEEAAIMKEMKH-PNLVQLLGVCT 459

Query: 91  KKSPPGNDDQLWLVMEFCGAGSVTDLVKNTKGNALKEDCIAYICREILRGLAHLHAHKVI 150
           ++ P       ++V EF   G++ D ++++         + Y+  +I  G+A+L     I
Sbjct: 460 REPP------FYIVTEFMPHGNLLDYLRSSTREENGPTALMYMATQIASGMAYLETKNFI 621

Query: 151 HRDIKGQNVLLTENAEVKLVDFGVSAQL-DRTVGRRNTFIGTPY---WMAPEVIACDENP 206
           HRD+  +N L+ ++  VK+ DFG++  + D T       IG  +   W APE +A +   
Sbjct: 622 HRDLAARNCLVADSNMVKVADFGLARLMKDDTY---TAHIGAKFPIKWTAPEGLAFNR-- 786

Query: 207 DATYDYRSDIWSLGITAIEMA 227
              +  RSDIW+ G+   E+A
Sbjct: 787 ---FSTRSDIWAFGVLLWELA 840
>01756
          Length = 1858

 Score = 84.3 bits (207), Expect = 3e-16,   Method: Compositional matrix adjust.
 Identities = 62/229 (27%), Positives = 106/229 (46%), Gaps = 17/229 (7%)
 Frame = -3

Query: 20   DPAGIFELVEVVGNGTYGQVYKGRHVKTGQLAAIK--VMD-------VTXXXXXXIKQEI 70
            D    +E +  +G GT+G+V+K R  KT Q+ A+K  +MD       +T      I Q +
Sbjct: 1751 DEDAKYEKLAKIGQGTFGEVFKARCKKTKQVVAMKKVLMDNEKEGFPITALREIKILQLL 1572

Query: 71   NMLKKYSHHRNIATYYGAFIKKSPPGN--DDQLWLVMEFCG---AGSVTDLVKNTKGNAL 125
            N       H N+         K+   N      +LV EFC    AG ++++        +
Sbjct: 1571 N-------HENVVDLIEICSTKATSANRYKSMFYLVFEFCEHDLAGLLSNMSVVFNLPEI 1413

Query: 126  KEDCIAYICREILRGLAHLHAHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRR 185
            KE     + ++++ GL ++H +K++HRD+K  N+L+T+   +KL DFG++      + + 
Sbjct: 1412 KE-----VMKQLMNGLYYIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQP 1248

Query: 186  NTF---IGTPYWMAPEVIACDENPDATYDYRSDIWSLGITAIEMAEGAP 231
            N +   + T ++  PE++  D N    Y    D W  G    EM    P
Sbjct: 1247 NRYTNRVVTLWYRPPELLLGDRN----YSTAIDQWGAGCIMAEMWTRNP 1113
>01718
          Length = 959

 Score = 84.0 bits (206), Expect = 4e-16,   Method: Compositional matrix adjust.
 Identities = 58/217 (26%), Positives = 109/217 (50%), Gaps = 5/217 (2%)
 Frame = +3

Query: 27  LVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTXXXXXXIKQEINMLKKYSHHRNIATYY 86
           + E +G G + +V+K  H  TGQ+ A+K+  +T      ++ E+ +L +   H NI  + 
Sbjct: 159 ICEKIGAGFFSEVFKVTHRITGQVMALKMNTMTSNRHNMLR-EVQLLNRL-QHANILRFM 332

Query: 87  GAFIKKSPPGNDDQLWLVMEFCGAGSVTDLVKNTKGNALKEDCIAYICREILRGLAHLHA 146
           G  +      ++ QL  + E+  +G++  L++  K   L       +   + RGL +LH+
Sbjct: 333 GVCV------HEGQLHALTEYIPSGNLEQLLEK-KDEELPWTQRIQLTLGLARGLDYLHS 491

Query: 147 HKVIHRDIKGQNVLL----TENAEVKLVDFGVSAQLDRTVGRRNT-FIGTPYWMAPEVIA 201
            + IHRD+  +N+L+           + DFG++ ++   + +     +G+PYWMAPEV+ 
Sbjct: 492 TRFIHRDLTSKNILIRREDNHGYHAVIADFGLATKIPDPLDKEKLPTVGSPYWMAPEVLN 671

Query: 202 CDENPDATYDYRSDIWSLGITAIEMAEGAPPLCDMHP 238
                   Y+ R+D++S+GI   E+    P   D+ P
Sbjct: 672 -----GHFYNERADLFSVGIIMCEITARIPADPDIMP 767
>01707
          Length = 757

 Score = 84.0 bits (206), Expect = 4e-16,   Method: Compositional matrix adjust.
 Identities = 62/209 (29%), Positives = 100/209 (47%), Gaps = 4/209 (1%)
 Frame = +1

Query: 25  FELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTXXXXXXIKQ----EINMLKKYSHHR 80
           +E +  +G G+YG V+K R+ +T QL AIK   V       IK+    EI MLK+  H  
Sbjct: 70  YEKIGKIGEGSYGVVFKCRNKETSQLVAIKKF-VESEDDPLIKKIAMREIRMLKQLKHP- 243

Query: 81  NIATYYGAFIKKSPPGNDDQLWLVMEFCGAGSVTDLVKNTKGNALKEDCIAYICREILRG 140
           N+      F +K       +L LV ++     + +L +  +G  L E  +  I  + L  
Sbjct: 244 NLVRLIEVFRRKK------RLHLVFDYVDHTLLNELDRYPRG--LPEPMVKRIIYQTLLA 399

Query: 141 LAHLHAHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVI 200
           +   H +  IHRD+K +N+L+T   +VKL DFG +  L         ++ T ++ APE++
Sbjct: 400 VNFCHQYNTIHRDVKPENILITRQGQVKLCDFGFARILTGPGDEYTDYVATRWYRAPELL 579

Query: 201 ACDENPDATYDYRSDIWSLGITAIEMAEG 229
                 D  Y    D+W++G    E+  G
Sbjct: 580 V----GDTQYGPPVDVWAIGCVFAELLTG 654
>14126
          Length = 1265

 Score = 83.2 bits (204), Expect = 7e-16,   Method: Compositional matrix adjust.
 Identities = 62/208 (29%), Positives = 103/208 (49%), Gaps = 6/208 (2%)
 Frame = +3

Query: 25  FELVEVVGNGTYGQVYKGRHVKT-GQLAAIKVMDVTXXXX---XXIKQEINMLKKYSH-- 78
           +E V V+GNG YG VYK R ++  G+  A+K + +            +EI+MLK+     
Sbjct: 195 YEEVAVIGNGAYGTVYKARDLRNQGEFVAMKRIRLNNTEEGMPMMAIREISMLKQLEQYE 374

Query: 79  HRNIATYYGAFIKKSPPGNDDQLWLVMEFCGAGSVTDLVKNTKGNALKEDCIAYICREIL 138
           H N+          +    + +L LV E+      T L K      L  D I  +  ++L
Sbjct: 375 HPNVVRLLDVS-HNTITDREIRLNLVFEYIEHDLATYLAK-CPSPGLGPDRIKDLMLQLL 548

Query: 139 RGLAHLHAHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPE 198
            G+  LH+++++HRD+K QN+L++++  +KL DFG+ A++        T + T ++ +PE
Sbjct: 549 NGVDFLHSNRIVHRDLKPQNLLISKDGRLKLADFGL-ARIYSFHMALTTVVVTLWYRSPE 725

Query: 199 VIACDENPDATYDYRSDIWSLGITAIEM 226
           V+       A Y    DIWS G    E+
Sbjct: 726 VLM-----QAEYGTSVDIWSCGCIFAEL 794
>01060
          Length = 1800

 Score = 80.9 bits (198), Expect = 3e-15,   Method: Compositional matrix adjust.
 Identities = 60/220 (27%), Positives = 99/220 (45%), Gaps = 3/220 (1%)
 Frame = +1

Query: 31  VGNGTYGQVYKGRHVKTGQLAAIKVMDVTXXXX---XXIKQEINMLKKYSHHRNIATYYG 87
           +G GTYG VYK RH  TG+  A+K + +            +EI ML++   H NI     
Sbjct: 97  IGEGTYGVVYKCRHRATGRKLAMKKIRLRGSEDGVPSSAIREIAMLREL-RHTNIVCLED 273

Query: 88  AFIKKSPPGNDDQLWLVMEFCGAGSVTDLVKNTKGNALKEDCIAYICREILRGLAHLHAH 147
             ++      D++L+LV EF        + K  +G  L    +     +I+ G+   H  
Sbjct: 274 VIME------DERLFLVFEFLSMDLKMYIDKFPEGVVLDRRLVKSYVFQIVTGIXFCHQR 435

Query: 148 KVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPD 207
           +++HRD+K QN+L+     +K+ DFG++      V      + T ++ APE++       
Sbjct: 436 RIVHRDLKPQNLLINHTGAIKIADFGMARTFALPVRAYTHEVVTLWYRAPEILM----GA 603

Query: 208 ATYDYRSDIWSLGITAIEMAEGAPPLCDMHPMRALFLIPR 247
           + Y    D+WS+G    +M    P       +  LF I R
Sbjct: 604 SKYSTPVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIFR 723
>09606
          Length = 1300

 Score = 79.3 bits (194), Expect = 9e-15,   Method: Compositional matrix adjust.
 Identities = 74/296 (25%), Positives = 124/296 (41%), Gaps = 32/296 (10%)
 Frame = -3

Query: 25   FELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTXXXXXXIKQEINMLKKYSH---HRN 81
            F L E +G G +  +YKGR   T    AI  ++         + E+    + +H   H N
Sbjct: 1109 FVLYEELGKGEHSIIYKGRRKGTINFVAIHCIEKCK------RPEVTNTVRMTHDISHPN 948

Query: 82   IATYYGAFIKKSPPGNDDQLWLVMEFCGAGSVTDLVKNTKGNALKEDCIAYICREILRGL 141
            +  ++  +         + LWLV+E C  GS+ D++   + + L E  I      ++ GL
Sbjct: 947  VVQFHEWY------ETSNHLWLVVELCTGGSLADIL--AQDHHLPETSIRDFGIHLVTGL 792

Query: 142  AHLHAHKVIHRDIKGQNVLLTENAEVKLVDFGVS----------------------AQLD 179
             ++H+  ++  D++   VLL  +  +K  DFG+S                       Q  
Sbjct: 791  HYIHSLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEAGDQWNIQSA 612

Query: 180  RTVGRRNTFIGTPYWMAPEVIACDENPDATYDYRSDIWSLGITAIEMAEGAPPLC----D 235
              + ++    G+P +MAPEV    E         SD+W+LG    EM  G PP      D
Sbjct: 611  EEMMKQVPTSGSPTYMAPEVFQGAEP-----SIMSDLWALGCVFYEMFSGHPPFLGETYD 447

Query: 236  MHPMRAL---FLIPRNPPPRLKSKKWSKKFTDFIDTCLIKTYLSRPPTEQLLKFPF 288
            +   + L   F +P+    RL +K  S +F + +++ L K    R     L+K  F
Sbjct: 446  ITKDKVLNKEFPLPKVKGSRLSAKP-SPEFLNLLESLLQKDSTRRLSWASLVKHAF 282
>21079
          Length = 878

 Score = 78.6 bits (192), Expect = 2e-14,   Method: Compositional matrix adjust.
 Identities = 42/132 (31%), Positives = 77/132 (58%), Gaps = 2/132 (1%)
 Frame = +1

Query: 103 LVMEFCGAGSVTDLVKNTKGNALKEDCIAYICREILRGLAHLHAHKVIHRDIKGQNVL-L 161
           LVMEF GAG + + V        + DC+ ++ R+I  G+ ++H   ++H D+K +NVL +
Sbjct: 55  LVMEFVGAGELFERVIRDDFVLTERDCVHFV-RQICSGVGYMHTQSILHLDLKPENVLCV 231

Query: 162 TENA-EVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDATYDYRSDIWSLG 220
           ++N+ ++K++DFG+ A+  +         GTP ++APEV+  DE      ++ +D+WS+G
Sbjct: 232 SDNSNQIKIIDFGL-ARFYKPGDSLQVLFGTPEFIAPEVVNYDE-----INFTTDMWSIG 393

Query: 221 ITAIEMAEGAPP 232
           +    +  G  P
Sbjct: 394 VICYILLSGLSP 429
>28638
          Length = 1458

 Score = 63.5 bits (153), Expect(2) = 2e-14,   Method: Compositional matrix adjust.
 Identities = 34/90 (37%), Positives = 52/90 (57%), Gaps = 2/90 (2%)
 Frame = -1

Query: 149 VIHRDIKGQNVLLT--ENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENP 206
           +IH D+K +N+LL   + + +K+VDFG S QL +   R   +I + ++ +PEV+      
Sbjct: 768 IIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQ---RIYQYIQSRFYRSPEVLL----- 613

Query: 207 DATYDYRSDIWSLGITAIEMAEGAPPLCDM 236
              YD   D+WSLG   +EM  G PPLC +
Sbjct: 612 GVPYDLAIDMWSLGCILVEMHTGEPPLCRL 523

 Score = 34.7 bits (78), Expect(2) = 2e-14,   Method: Compositional matrix adjust.
 Identities = 29/120 (24%), Positives = 54/120 (45%)
 Frame = -3

Query: 25   FELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTXXXXXXIKQEINMLKKYSHHRNIAT 84
            +E+  ++G G++GQV K       +  AIK++          + E+ +L+  + H     
Sbjct: 1141 YEIDSLIGKGSFGQVVKAYDHGDQEQVAIKIIKNKKPFLNQAQIEVKLLELMNRHDADNX 962

Query: 85   YYGAFIKKSPPGNDDQLWLVMEFCGAGSVTDLVKNTKGNALKEDCIAYICREILRGLAHL 144
            YY   +K+      + L LV E   + ++ DL++NT          + IC  ++ G A L
Sbjct: 961  YYIVRLKRHFMFR-NHLCLVFELL-SYNLYDLLRNTNFRGGLPQLDS*ICSAVVYGAAVL 788
>04852
          Length = 1462

 Score = 77.0 bits (188), Expect = 5e-14,   Method: Compositional matrix adjust.
 Identities = 72/276 (26%), Positives = 115/276 (41%), Gaps = 33/276 (11%)
 Frame = +1

Query: 42  GRHVKTGQLAAIKVMD-VTXXXXXXIKQEINMLK---KYSHHRNIATYYGAFIKKSPPGN 97
           GR  K   +A   + D VT        QE+ ++K   K   H NI  + G   +  P   
Sbjct: 4   GRVPKASTVAVKMLRDIVTAVEEQDFVQELQVMKAVKKMGSHINIVNFLGCCTQGGP--- 174

Query: 98  DDQLWLVMEFCGAGSVTDLVKNTK-----------------------GNALKEDCIAYIC 134
              LW+++EF   G++ D +++ +                       G+ ++   +    
Sbjct: 175 ---LWVIVEFAKNGNLRDFLESCRDGINGYGKFVSPQDPGWYTKTPGGHVIRRKNLLSYA 345

Query: 135 REILRGLAHLHAHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYW 194
            +I RG+  L + K IHRD+  +NVL+TE   +K+ DFG+S   D    R    +    W
Sbjct: 346 FQIARGMEFLASRKCIHRDLAARNVLVTEEHVLKIADFGLSRTGDYYKKRSGGRLPVK-W 522

Query: 195 MAPEVIACDENPDATYDYRSDIWSLGITAIEM-AEGAPPLCDMHPMRALF--LIP---RN 248
           MAPE +      D  Y  +SD+WS G+   E+ + G  P   + P   L+  L+    R 
Sbjct: 523 MAPEALF-----DMRYTTKSDVWSFGVVLWEIFSLGGMPYASI-PNEELYSKLLDDAYRM 684

Query: 249 PPPRLKSKKWSKKFTDFIDTCLIKTYLSRPPTEQLL 284
           P P L     S      ++ C +     RP   QL+
Sbjct: 685 PRPELA----SGNLYAIMERCWLNRPSDRPEFSQLV 780
>03240
          Length = 1683

 Score = 75.9 bits (185), Expect = 9e-14,   Method: Compositional matrix adjust.
 Identities = 65/258 (25%), Positives = 107/258 (41%), Gaps = 48/258 (18%)
 Frame = -3

Query: 24   IFELVEVVGNGTYGQVYKGRHVKTGQLAAIKVM---DVTXXXXXX-IKQEINMLKKYSHH 79
            +FE ++ +G G +G+V   R   TG L A+K +   DV        +K E ++L +  + 
Sbjct: 1288 MFEKIKTLGVGAFGEVSLCRKNDTGMLYAMKTLRKSDVLKRNQVAHVKAERDILAEADNE 1109

Query: 80   RNIATYYGAFIKKSPPGNDDQLWLVMEFCGAGSVTDLVKNTKGNALKEDCIAYICREILR 139
              +  YY          + + L+ VM++   G +  L+   +   L E    +   E+++
Sbjct: 1108 WVVKLYYSF-------QDHNYLYFVMDYVPGGDLMGLL--IRMEILDEPLARFYVAELVQ 956

Query: 140  GLAHLHAHKVIHRDIKGQNVLLTENAEVKLVDFG-------------------------- 173
             +  +H    IHRDIK  N+L+  N  +KL DFG                          
Sbjct: 955  AIESVHRMGFIHRDIKPDNILIDRNGHIKLTDFGLCTGFRWTHNSKYYQRDGTHARQDSM 776

Query: 174  -VSAQLD--------RTVGRR---------NTFIGTPYWMAPEVIACDENPDATYDYRSD 215
             V  QLD        + + RR         ++ +GTP ++APEV++        Y    D
Sbjct: 775  EVKCQLDEQCQCEILKPLERRRKREQRCLAHSLVGTPNYIAPEVLS----RLGGYTSVCD 608

Query: 216  IWSLGITAIEMAEGAPPL 233
             WS+G+   EM  G PP 
Sbjct: 607  WWSVGVILFEMLVGHPPF 554
>12786
          Length = 460

 Score = 74.3 bits (181), Expect = 3e-13,   Method: Compositional matrix adjust.
 Identities = 43/121 (35%), Positives = 64/121 (52%), Gaps = 17/121 (14%)
 Frame = -3

Query: 130 IAYICREILRGLAHLHAHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQL--DRTVGRRNT 187
           I +  RE+LR +  LH   VIH D+K  N +L     +KL+DFG++  L  D+T   +++
Sbjct: 404 IKFYWREMLRAVKALHNEGVIHSDLKPANFMLVA-GNLKLIDFGIANTLQQDKTSVLKDS 228

Query: 188 FIGTPYWMAPEVI--ACDENPDATYD-------------YRSDIWSLGITAIEMAEGAPP 232
            +GTP +M+PE I  ACD++ D + +              RSD+WSLG     M  G  P
Sbjct: 227 RVGTPSYMSPEAIMAACDDSADDSMEEDGHRTKPKYKVGVRSDVWSLGCILYNMVYGRTP 48

Query: 233 L 233
            
Sbjct: 47  F 45
>30755
          Length = 1137

 Score = 71.2 bits (173), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 46/128 (35%), Positives = 66/128 (51%), Gaps = 8/128 (6%)
 Frame = +2

Query: 136 EILRGLAHLHAHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRN-TFIGTPYW 194
           EI+  L +LH+  +I+RD+K +N+LL ++  +K+ DFG+  + D T GR   TF GTP +
Sbjct: 56  EIISALGYLHSQGIIYRDLKLENLLLDKDGHIKVADFGLCKE-DITYGRTTKTFCGTPEY 232

Query: 195 MAPEVIACDENPDATYDYRSDIWSLGITAIEMAEGAPPLC--DMHPMRALFLI-----PR 247
           +APEV+      D  Y    D W  G+   EM  G  P    D   +  L L+     PR
Sbjct: 233 LAPEVLD-----DNDYGRAVDWWGTGVVMYEMICGRLPFYNRDHDVLFTLILVEDVKFPR 397

Query: 248 NPPPRLKS 255
           N     KS
Sbjct: 398 NITDEAKS 421
>00392
          Length = 668

 Score = 70.9 bits (172), Expect = 3e-12,   Method: Compositional matrix adjust.
 Identities = 51/170 (30%), Positives = 87/170 (51%), Gaps = 3/170 (1%)
 Frame = +3

Query: 66  IKQEINMLKKYSHHRNIATYYGAFIKKSPPGNDDQLWLVMEFCGAGSVTDLVKNTKGNAL 125
            K+E  MLK+   H NI  ++  + ++    N   + LV E   +G++   +K  K   +
Sbjct: 72  FKEEAEMLKEL-QHPNIVRFFD-YWEEHNHRNRKVIILVTELMTSGTLKTYLKRFKKPNV 245

Query: 126 KEDCIAYICREILRGLAHLHAHK--VIHRDIKGQNVLLT-ENAEVKLVDFGVSAQLDRTV 182
           K   +   CR++L+GL  LH     VIHRD+K  N+ +T     VK+ D G++   +++ 
Sbjct: 246 K--ILKNWCRQVLKGLYFLHTRTPPVIHRDLKCDNIFITGPTGSVKIGDLGLATLKNQSF 419

Query: 183 GRRNTFIGTPYWMAPEVIACDENPDATYDYRSDIWSLGITAIEMAEGAPP 232
            +  + IGTP +MAPE+       +  YD   D+++ G+  +EMA    P
Sbjct: 420 AK--SVIGTPEFMAPEMY------EEHYDEAVDVYAFGMCMLEMASSEYP 545
>18484
          Length = 635

 Score = 70.1 bits (170), Expect = 6e-12,   Method: Compositional matrix adjust.
 Identities = 37/109 (33%), Positives = 52/109 (47%)
 Frame = +1

Query: 125 LKEDCIAYICREILRGLAHLHAHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGR 184
            KE   A+   EI  GL  LH   +I+RD+K  NV+L     +K+ DFG+  +       
Sbjct: 34  FKEPVAAFYAAEIAVGLFFLHDQGIIYRDLKLDNVMLDSEGHIKIADFGMCKEGMTGDAT 213

Query: 185 RNTFIGTPYWMAPEVIACDENPDATYDYRSDIWSLGITAIEMAEGAPPL 233
             TF GTP ++APE++         Y    D W+ G+   EM  G PP 
Sbjct: 214 TRTFCGTPDYIAPEIVLYQ-----PYSKSVDWWAYGVLLFEMLAGQPPF 345
>31885
          Length = 529

 Score = 70.1 bits (170), Expect = 6e-12,   Method: Compositional matrix adjust.
 Identities = 47/165 (28%), Positives = 82/165 (49%), Gaps = 1/165 (0%)
 Frame = -2

Query: 70  INMLKKYSHHRNIATYYGAFIKKSPPGNDDQLWLVMEFCGAGSVTDLVKNTKGN-ALKED 128
           ++ML +  H   +  +Y AF       +++ L++V++    G   DL  + +   + +ED
Sbjct: 519 VDMLTRLDHPFLVNLWY-AF------QDEEDLFMVVDLFLGG---DLRYHMQQEVSFRED 370

Query: 129 CIAYICREILRGLAHLHAHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTF 188
           C+ +   ++   L +L + K++HRDIK  N+LL E     + DF ++ QL+      +T 
Sbjct: 369 CVKFYLCQLALVLDYLRSQKIVHRDIKPDNILLDEQGHCHVTDFNIATQLEDDELATSTS 190

Query: 189 IGTPYWMAPEVIACDENPDATYDYRSDIWSLGITAIEMAEGAPPL 233
              PY MAPEV     N    Y +  D WSLG++  E+ +   P 
Sbjct: 189 GTRPY-MAPEVYGVAINERRGYGFPVDWWSLGVSLFELLKKRRPF 58
>21808
          Length = 1011

 Score = 68.9 bits (167), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 51/180 (28%), Positives = 84/180 (46%), Gaps = 5/180 (2%)
 Frame = +1

Query: 51  AAIKVMDVTXXXXXXIKQEINMLKKYSHHRNIATYYGAFIKKSPPGNDDQLWLVMEFCGA 110
            AIK +            E  ++KK  H + I  Y       +    DD ++++ E    
Sbjct: 28  VAIKTLKSGTMDPKDFLAEAQIMKKLRHPKLIQLY-------AVCTQDDPIFIITELMKN 186

Query: 111 GSVTDLVKNTKGNALKEDCIAYICREILRGLAHLHAHKVIHRDIKGQNVLLTENAEVKLV 170
           GS+ + ++  KG  LK   +  I  +I  G+A+L +   IHRD+  +N+L+++N  VK+ 
Sbjct: 187 GSLLEFLQG-KGRVLKLPALIDIGAQIACGMAYLESQNYIHRDLAARNILVSDNNTVKIA 363

Query: 171 DFGVSA-----QLDRTVGRRNTFIGTPYWMAPEVIACDENPDATYDYRSDIWSLGITAIE 225
           DFG++      + +  VG R        W APE  A + N    +  +SD+WS GI   E
Sbjct: 364 DFGLARVIKEDEYEARVGARFPI----KWTAPE--AANYN---RFTIKSDVWSFGILLTE 516
>00715
          Length = 1788

 Score = 67.8 bits (164), Expect = 3e-11,   Method: Compositional matrix adjust.
 Identities = 60/230 (26%), Positives = 100/230 (43%), Gaps = 28/230 (12%)
 Frame = +1

Query: 79  HRNIATYYGAFIKKSPPGNDDQLWLVMEFCGAGSVTDLVKNTKGNALKEDCIAYICREIL 138
           H N+ +  GA    S    +D  WL ME+ G  ++  ++ + + + +       +  ++ 
Sbjct: 103 HVNVVSILGA---TSLHRFEDGAWLAMEYVGPLNLQTILNDHQQD-IDSSMRLSLALQMA 270

Query: 139 RGLAHLHAHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRT---VGRR---------- 185
           RGL +LH+  ++H D+K  N LLT + ++++ DFG   QL  T   +G R          
Sbjct: 271 RGLHYLHSINIVHLDLKPANCLLTRDLKLRIADFGCCHQLTPTGLDMGEREGGMAGNELE 450

Query: 186 ---------NTFIGTPYWMAPEVIACDENPDATYDYRSDIWSLGITAIEMA------EGA 230
                    N   GT  + APE++     P      RSD++SLGIT  +M       EG 
Sbjct: 451 LTPVQGAWKNELAGTLAYRAPELLK-GLQPSV----RSDVYSLGITLWQMCTRQGPYEGV 615

Query: 231 PPLCDMHPMRALFLIPRNPPPRLKSKKWSKKFTDFIDTCLIKTYLSRPPT 280
           P    ++ + +  L P  PPP  +   +   F D    C  +    RP +
Sbjct: 616 PAHAVVYQVVSKDLRP-CPPPSTEDDPFEVMFRDLYTQCWARRVEDRPTS 762
>29581
          Length = 1278

 Score = 67.4 bits (163), Expect = 4e-11,   Method: Compositional matrix adjust.
 Identities = 45/153 (29%), Positives = 74/153 (48%)
 Frame = -2

Query: 79   HRNIATYYGAFIKKSPPGNDDQLWLVMEFCGAGSVTDLVKNTKGNALKEDCIAYICREIL 138
            H+NI       + KS     D L+LVME+C    +  L+ N       E  +  I  ++L
Sbjct: 1178 HQNIVQLQEVVVGKSL----DSLFLVMEYC-EQDLASLLDNMPA-PFSESQVKCIVLQLL 1017

Query: 139  RGLAHLHAHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPE 198
            +GL +LH   +IHRD+K  N+L+T+   VK+ DFG++    +        + T ++ APE
Sbjct: 1016 KGLRYLHEAFIIHRDLKVSNLLMTDKGCVKIADFGLARNYGKPQKPMTPKVVTLWYRAPE 837

Query: 199  VIACDENPDATYDYRSDIWSLGITAIEMAEGAP 231
            ++   +    T+    D+WS G    E+    P
Sbjct: 836  LLFGSK----THSTAIDMWSAGCILGELLGHKP 750
>15910
          Length = 1361

 Score = 67.4 bits (163), Expect = 4e-11,   Method: Compositional matrix adjust.
 Identities = 41/117 (35%), Positives = 71/117 (60%), Gaps = 3/117 (2%)
 Frame = +2

Query: 120 TKGNALKEDCIAYICREILRGLAHLHAHKVIHRDIKGQNVL---LTENAEVKLVDFGVSA 176
           T+G   ++D    I  +IL G+ ++HA+ V+HRD+K +N+L   +T+++++KL DFG+S 
Sbjct: 443 TRGQYTEKDAARAI-SDILHGVQYIHANGVVHRDLKPENLLYECMTDDSKLKLADFGLSR 619

Query: 177 QLDRTVGRRNTFIGTPYWMAPEVIACDENPDATYDYRSDIWSLGITAIEMAEGAPPL 233
            ++  V + +T  GTP + APEV+  D+     Y    D+WS+G+ A  +  G  P 
Sbjct: 620 IIEPEV-QMSTVCGTPGYCAPEVLKGDK-----YTPSVDMWSVGVIAYILLCGYEPF 772
>01392
          Length = 1806

 Score = 67.0 bits (162), Expect = 5e-11,   Method: Compositional matrix adjust.
 Identities = 58/193 (30%), Positives = 85/193 (44%), Gaps = 25/193 (12%)
 Frame = -1

Query: 131  AYICREILRGLAHLHAHKVIHRDIKGQNVL---LTENAEVKLVDF----GVSAQLDRT-V 182
            + + R I R L  LH+  + HRD+K +N+L   L +   VK+ DF    G+S   D T  
Sbjct: 1782 SLVVRHIARALDFLHSKGIAHRDLKPENILCEHLDDVVPVKICDFDLASGISCDGDGTKT 1603

Query: 183  GRRNTFIGTPYWMAPEVIACDENPDATYDYRSDIWSLGITAIEMAEGAPPL-------CD 235
                T +G+  +MAPEV+        +YD R D+WSLGI    M  G PP        C 
Sbjct: 1602 PELLTPVGSAEYMAPEVVDAWVGDSFSYDKRCDLWSLGIILYIMLCGYPPFYGQCGEDCG 1423

Query: 236  MHPMRA-------LFLIPRNPPPRLKSKKW---SKKFTDFIDTCLIKTYLSRPPTEQLLK 285
             +   A       LF   ++   +  S++W   S    D I   L++    R     +LK
Sbjct: 1422 WNRGEACHDCQDMLFNSIQDGHYKFPSQEWTSISSSAKDLIRHLLVREPRKRYSAADVLK 1243

Query: 286  FPFIRDQPTERQV 298
             P+I   P   Q+
Sbjct: 1242 HPWICTPPAATQL 1204
>14116
          Length = 1017

 Score = 66.2 bits (160), Expect = 7e-11,   Method: Compositional matrix adjust.
 Identities = 55/208 (26%), Positives = 93/208 (44%), Gaps = 10/208 (4%)
 Frame = -1

Query: 29  EVVGNGTYGQVYKGRHV----KTGQLAAIKVMDVTXXXXXXIK---QEINMLKKYSHHRN 81
           E +G G +G V +G       K   L A+K +         ++   QE  ++K + HH N
Sbjct: 618 EEIGKGNFGCVKRGFLTLPEQKGDILVAVKTLHNNNPREIELQSFLQEALIMKDF-HHSN 442

Query: 82  IATYYGAFIKKSPPGNDDQLWLVMEFCGAGSVTDLVKNTKGNALKEDCIAYICREILRGL 141
           + T  G  +       DD   +V+ F   G +   +++ +     +D I Y   +I RG+
Sbjct: 441 VLTLIGICLNL-----DDMPLVVLPFMKHGDLLTYIRDDQHQPTIKDLIMY-GVDIARGM 280

Query: 142 AHLHAHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQL--DRTVGRRNTFIGTPY-WMAPE 198
            +L   K +HRD+  +N +L E+  VK+ DFG++  +         N     P  WMA E
Sbjct: 279 DYLAGLKFVHRDLAARNCMLDEDFHVKVADFGLARDIYEKEYYSSENKKAKLPVKWMALE 100

Query: 199 VIACDENPDATYDYRSDIWSLGITAIEM 226
            +         YD ++D+WS G+   E+
Sbjct: 99  SL-----EKGNYDSKTDVWSYGVVLWEL 31
>19301
          Length = 712

 Score = 66.2 bits (160), Expect = 8e-11,   Method: Compositional matrix adjust.
 Identities = 44/148 (29%), Positives = 82/148 (55%)
 Frame = +2

Query: 28  VEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTXXXXXXIKQEINMLKKYSHHRNIATYYG 87
           +E +G+G  G V+ G+ +   ++A  KV D+        + +I  L+K  +H NI ++ G
Sbjct: 320 LEWLGSGAQGAVFLGK-LCAEEVAVKKVRDIK-------ETDIRNLRKL-NHPNIISFKG 472

Query: 88  AFIKKSPPGNDDQLWLVMEFCGAGSVTDLVKNTKGNALKEDCIAYICREILRGLAHLHAH 147
               ++P        ++ME+C  G + +++++  G  +    +    ++I  G+ +LH+H
Sbjct: 473 V-CTQAPC-----YCIIMEYCPYGQLYEVLRD--GKEIPPALVLDWSKQIASGMNYLHSH 628

Query: 148 KVIHRDIKGQNVLLTENAEVKLVDFGVS 175
           K+IHRD+K  NVL+ +N  VK+ DFG S
Sbjct: 629 KIIHRDLKSPNVLVAKNDVVKISDFGTS 712
>26560
          Length = 398

 Score = 65.5 bits (158), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 33/114 (28%), Positives = 60/114 (52%)
 Frame = -1

Query: 120 TKGNALKEDCIAYICREILRGLAHLHAHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLD 179
           ++     E  + +   E++ GL H+H+  V++RD+K  N+LL EN  V++ D G++    
Sbjct: 380 SQHGVFTEKEVRFYAAEVMLGLEHMHSRFVVYRDLKPANILLDENGHVRISDLGLACDFS 201

Query: 180 RTVGRRNTFIGTPYWMAPEVIACDENPDATYDYRSDIWSLGITAIEMAEGAPPL 233
           +   R +  +GT  +MAPEV+        +YD  +D +S G    ++ +G  P 
Sbjct: 200 KK--RPHASVGTHGYMAPEVLM----KGQSYDSSADWFSFGCMLYKLLKGHSPF 57
>11780
          Length = 1713

 Score = 62.8 bits (151), Expect = 9e-10,   Method: Compositional matrix adjust.
 Identities = 47/179 (26%), Positives = 91/179 (50%), Gaps = 3/179 (1%)
 Frame = +3

Query: 25  FELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTXXXXXXIKQEINMLKKYSHHRNIAT 84
            E+ E +G G +G VYKG +   GQ  AIK +           QE +++    H  N+  
Sbjct: 603 LEIGEAIGKGDFGDVYKGMY--RGQPVAIKQLKDKDRGEQSFLQEASVMTSLRHD-NLVR 773

Query: 85  YYGAFIKKSPPGNDDQLWLVMEFCGAGSVTDLVKNTKGNAL--KEDCIAYICREILRGLA 142
             G  + ++       ++LV EF G G++ + ++ ++G ++  K+D I +   +    + 
Sbjct: 774 LIGVVLGET-------IFLVTEFMGKGNLVEYLR-SRGRSVITKKDQINF-ATDTCAAME 926

Query: 143 HLHAHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPY-WMAPEVI 200
           +L + +++HRD+  +NVL+ ++ + K+ DFG++   D +     T +  P  W APE +
Sbjct: 927 YLESKRLVHRDLAARNVLVHDDGKAKVSDFGLAKFGDFS----QTSVKFPIKWTAPEAL 1091
>07940
          Length = 1336

 Score = 61.6 bits (148), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 35/102 (34%), Positives = 56/102 (54%), Gaps = 2/102 (1%)
 Frame = -3

Query: 127 EDCIAYICREILRGLAHLHAHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRN 186
           +D I+Y   ++ RG+ +L + + IHRD+  +NVL+ E   +K+ DFG++  L +    R 
Sbjct: 347 KDLISY-AYQVARGMEYLASKQCIHRDLAARNVLVAEEYVLKIADFGLTRNLQQFDYYRK 171

Query: 187 TFIGT--PYWMAPEVIACDENPDATYDYRSDIWSLGITAIEM 226
           T  G     WMAPE +      D  Y  +SD+WS G+   E+
Sbjct: 170 TTDGRLPVKWMAPEALF-----DRKYTSKSDVWSYGVLLWEI 60
>04591
          Length = 1117

 Score = 61.2 bits (147), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 46/170 (27%), Positives = 85/170 (50%), Gaps = 6/170 (3%)
 Frame = -2

Query: 68   QEINMLKKYSHHRNIATYYGAFIKKSPPGN--DDQLWLVMEFCG---AGSVTDL-VKNTK 121
            +EI +L++  H  N+         ++ P N      +L+ E+C    AG + +L VK + 
Sbjct: 1074 REIKILQQLEHE-NVVQLQEICHTQAGPYNRYKSTFYLIFEYCDYDLAGLLNNLRVKFSL 898

Query: 122  GNALKEDCIAYICREILRGLAHLHAHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRT 181
             +  K++ ++    ++L GL ++H  +++HRDIK  N+LLT +  +KL DFG+S    ++
Sbjct: 897  AD--KKNLMS----QLLNGLFYIHTKQILHRDIKAANILLTRDGVLKLADFGLSRPWVKS 736

Query: 182  VGRRNTFIGTPYWMAPEVIACDENPDATYDYRSDIWSLGITAIEMAEGAP 231
              R    + T ++  PE++  +      Y    D+W +G    EM    P
Sbjct: 735  -KRLTNRVVTLWYRPPELLLGERE----YGPEIDMWGVGCIMAEMWSRKP 601
>17975
          Length = 449

 Score = 60.8 bits (146), Expect = 3e-09,   Method: Composition-based stats.
 Identities = 44/147 (29%), Positives = 70/147 (47%), Gaps = 4/147 (2%)
 Frame = +3

Query: 36  YGQVYKGRHVKTGQLAAIKVMDVTX---XXXXXIKQEINMLKKYSHHRNIATYYGAFIKK 92
           +  V   RHV TG+  A+KV+D T         + QE+  +K    H N+   Y     +
Sbjct: 6   FAVVKLARHVFTGEKVAVKVIDKTKLDEVSRSHLFQEVRCMK-LVQHPNVVRLYEVIDTQ 182

Query: 93  SPPGNDDQLWLVMEFCGAGSVTDLVKNTKGNALKEDCIAYICREILRGLAHLHAHKVIHR 152
           +      +L+L++E    G + D +    G  L+E       R+I+  +++ H   V+HR
Sbjct: 183 T------KLYLILELGDGGDMYDYIMRHSG-GLEEKLAKRYFRQIVEAISYCHKLHVVHR 341

Query: 153 DIKGQNVLLTEN-AEVKLVDFGVSAQL 178
           D+K +NV+  E    VKL DFG S  L
Sbjct: 342 DLKPENVVFFEKPGLVKLTDFGFSTCL 422
>21433
          Length = 590

 Score = 60.5 bits (145), Expect = 4e-09,   Method: Compositional matrix adjust.
 Identities = 39/105 (37%), Positives = 55/105 (52%)
 Frame = +2

Query: 129 CIAYICREILRGLAHLHAHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTF 188
           C  Y   ++   L + H  KVIHRDIK +N+LL    ++K+ DFG S     +  RR T 
Sbjct: 179 CYIY---QLSSALEYCHYRKVIHRDIKPENLLLGLKGDLKIADFGWSVHAPSS--RRTTM 343

Query: 189 IGTPYWMAPEVIACDENPDATYDYRSDIWSLGITAIEMAEGAPPL 233
            GT  ++ PE++        T+D   D+WSLG+   E   G PPL
Sbjct: 344 CGTLDYLPPEMVE-----GKTHDENVDLWSLGVLCYEFLVGTPPL 463
>19761
          Length = 473

 Score = 60.5 bits (145), Expect = 4e-09,   Method: Compositional matrix adjust.
 Identities = 42/153 (27%), Positives = 77/153 (50%), Gaps = 4/153 (2%)
 Frame = -3

Query: 124 ALKEDCIAYICREILRGLAHLHAHK--VIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRT 181
            L E  I     +    L ++H H   ++HRD+K QN+ +TE  +V+L D G++ +L   
Sbjct: 435 GLPERLIVCWLMQTASALNYMHTHTPVILHRDLKPQNIYVTEKGDVRLGDLGLARKLTGP 256

Query: 182 VGRRNTFIGTPYWMAPEVIACDENPDATYDYRSDIWSLGITAIEMA--EGAPPLCDMHPM 239
                + +GT  +++PE+++  + P   Y+ +SDIWSLG    ++   +G+  +  M  +
Sbjct: 255 ADFATSQVGTIMYLSPEILS--QQP---YNSKSDIWSLGCVFYDITGKKGSDEMGVMFLL 91

Query: 240 RALFLIPRNPPPRLKSKKWSKKFTDFIDTCLIK 272
             +    + P P      +S++F D I   L K
Sbjct: 90  VQVMGGRKLPLP----DHYSQEFRDTISRMLTK 4
>01966
          Length = 1735

 Score = 60.5 bits (145), Expect = 4e-09,   Method: Compositional matrix adjust.
 Identities = 43/172 (25%), Positives = 77/172 (44%)
 Frame = -1

Query: 68   QEINMLKKYSHHRNIATYYGAFIKKSPPGNDDQLWLVMEFCGAGSVTDLVKNTKGNALKE 127
            +EI ML++   H NI       ++      D++L+LV EF        + K  +G  L  
Sbjct: 1567 REIAMLREL-RHTNIVCLEDVIME------DERLFLVFEFLSMDLKMYIDKFPEGVVLDR 1409

Query: 128  DCIAYICREILRGLAHLHAHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNT 187
              +     +I+ G+   H  +++HRD+K QN+L+     +K+ DFG++      V     
Sbjct: 1408 RLVKSYVFQIVTGINFCHQRRIVHRDLKPQNLLINHTGAIKIADFGMARTFALPVRAYTH 1229

Query: 188  FIGTPYWMAPEVIACDENPDATYDYRSDIWSLGITAIEMAEGAPPLCDMHPM 239
             + T ++ APE++     P +T       W+ G       E + P+C   P+
Sbjct: 1228 EVVTLWYRAPEILM---GPQST----PPXWTCG-----ALEPSSPICSSGPL 1109
>27405
          Length = 532

 Score = 59.7 bits (143), Expect = 7e-09,   Method: Compositional matrix adjust.
 Identities = 46/185 (24%), Positives = 89/185 (48%), Gaps = 8/185 (4%)
 Frame = -3

Query: 36  YGQVYKGRHVKTGQLAAIKVMD-----VTXXXXXXIKQEINMLKKYSHHRN---IATYYG 87
           +G+VY  R   TG++ A+K +D     +       + + I ML   S       I     
Sbjct: 527 FGEVYGCRKADTGKMYAMKCLDKKRIKMKGGETLALNERI-MLSLVSTGEGSPFIVCMTY 351

Query: 88  AFIKKSPPGNDDQLWLVMEFCGAGSVTDLVKNTKGNALKEDCIAYICREILRGLAHLHAH 147
           AF  ++P    ++L  +++    G +      ++     E  + +   E++ GL H+H+ 
Sbjct: 350 AF--QTP----EKLCFILDLMNGGDLH--YHLSQHGVFTEKEVRFYAAEVMLGLEHMHSR 195

Query: 148 KVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPD 207
            V++RD+K  N+LL EN  V++ D G++    +   + +  +GT  +MAPEV+   +  D
Sbjct: 194 FVVYRDLKPANILLDENGHVRISDLGLACDFSKK--KPHASVGTHGYMAPEVLMKGQAYD 21

Query: 208 ATYDY 212
           ++ D+
Sbjct: 20  SSADW 6
>17253
          Length = 483

 Score = 58.9 bits (141), Expect = 1e-08,   Method: Composition-based stats.
 Identities = 38/155 (24%), Positives = 69/155 (44%), Gaps = 12/155 (7%)
 Frame = -1

Query: 44  HVKTGQLAAIKVMD--VTXXXXXXIKQEINMLKKYSHHRNIATYYGAFIKKSPPGNDDQL 101
           H +     A+K  +   T        +E+++++K   H N+ ++ G      P       
Sbjct: 480 HARQWDTVAVKTHNEAATDAEKSEFLRELSIMRKLPRHPNVVSFMGCCTMSDPA------ 319

Query: 102 WLVMEFCGAGSVTDLVKNTK----------GNALKEDCIAYICREILRGLAHLHAHKVIH 151
            ++MEFC  G +   ++  +           N L           + RG+AH+  +K++H
Sbjct: 318 LILMEFCCHGDLLSFLRKRRPDRTVFLTSTANDLTARDFFSFALHVARGMAHVANNKIVH 139

Query: 152 RDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRN 186
           RD+  +NVL++E    K+ DFG+S    R VG +N
Sbjct: 138 RDVAARNVLISERNVCKVSDFGLS----RRVGDQN 46
>09007
          Length = 1440

 Score = 58.5 bits (140), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 63/283 (22%), Positives = 117/283 (41%), Gaps = 19/283 (6%)
 Frame = -1

Query: 27  LVEVVGNGTYGQVYKG-RHVKTGQLAAIKVMDVTXXXXXXIKQEI---NMLKKYSHHRNI 82
           L + +G G +G V +     ++G+   + V  ++        QE      + +   H NI
Sbjct: 867 LSKSLGQGHFGTVRQAIWTAESGEKVQVAVKCLSKDKIHKDGQEFLKETAIMQMLDHENI 688

Query: 83  ATYYGAFIKKSPPGNDDQLWLVMEFCGAGSVTDLVKNTKGNALKEDCIAYIC---REILR 139
              YG  +      N   + LV E     S+ + VK    +A  +  +  +C   +++  
Sbjct: 687 VRVYGVVMD-----NGADIMLVTELAPMRSLLECVKEV--SARVDFSVPRLCDFSQQVCD 529

Query: 140 GLAHLHAHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQL---------DRTVGRRNTFIG 190
           G+++L + +++HRD+  +N+LL   ++VK+ D GVS  L          +T+  +N    
Sbjct: 528 GMSYLESKRLVHRDLAARNILLFSKSKVKISDVGVSGALGAGKEYYQSQQTIHLQNAVA- 352

Query: 191 TPYWMAPEVIACDENPDATYDYRSDIWSLGITAIE-MAEGAPPLCDMHPMRALFLIPRNP 249
              W APE        +  +   SD+W+ G+   E    G  P   ++  + +  +    
Sbjct: 351 ---WCAPESFR-----NLCFSSASDVWAFGVLLWEFFTHGFQPWAGLNGQQIMEAVDAPQ 196

Query: 250 PPRLKSKKWS-KKFTDFIDTCLIKTYLSRPPTEQL-LKFPFIR 290
             RL+      K++   +  C  +    RP   QL L  P IR
Sbjct: 195 SQRLEQPDLCPKEYYAVMLKCWEQEPQRRPTFSQLFLTLPQIR 67
>13066
          Length = 551

 Score = 58.2 bits (139), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 52/199 (26%), Positives = 95/199 (47%), Gaps = 8/199 (4%)
 Frame = +3

Query: 30  VVGNGTYGQVYKGRHVKTGQLAAIKVMDVTXXXXXXIKQ----EINMLKKYSHHRNIATY 85
           VV +GT+   Y GR++K     A K++D        +++    E+++L K  H   I  +
Sbjct: 12  VVVHGTFNDGY-GRNIKL----ACKIIDKEKAPVDFVEKFFPRELDLLTKLDHPYIIQIH 176

Query: 86  YGAFIKKSPPGNDDQLWLVMEFCGAGSVTDLVKNTKGNALKEDCIAYICREILRGLAHLH 145
             + +++ P       ++ M F   G +   ++       K+  I +   ++   L +LH
Sbjct: 177 --SILQRXPKN-----FIFMRFAERGDLLTYIQEVGFVKEKQAKIWF--YQMTTALNYLH 329

Query: 146 AHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRR---NTFIGTPYWMAPEVIAC 202
           ++ V HRD+K +N+LL+ +  VKL DFG +       G +    T+ G+  + APE++  
Sbjct: 330 SYDVAHRDLKCENILLSSHFNVKLADFGFACACITESGEKYMSRTYCGSAAYAAPEIVY- 506

Query: 203 DENPDATYDYR-SDIWSLG 220
                A Y  + +D WSLG
Sbjct: 507 ----GAPYAPKVADAWSLG 551
>26711
          Length = 405

 Score = 56.6 bits (135), Expect = 6e-08,   Method: Composition-based stats.
 Identities = 36/105 (34%), Positives = 60/105 (57%), Gaps = 4/105 (3%)
 Frame = -2

Query: 133 ICREILRGLAHLHAHKVIHRDIKGQNVLLTENA--EVKLVDFGVSAQLDRTVGRRNTFI- 189
           + +++L  L H+HA  V+H D+K  N+LL+ +    V+L+DFG++ +L      + TF+ 
Sbjct: 401 VVKQVLDILQHVHAQGVVHMDLKPSNLLLSGDKLDSVQLIDFGLARKL---YPPQETFLN 231

Query: 190 -GTPYWMAPEVIACDENPDATYDYRSDIWSLGITAIEMAEGAPPL 233
            GTP + +PE  A D  P +T    SD+W +G+ A  +  G  P 
Sbjct: 230 HGTPGFTSPE--ALDVKPIST---ASDVWGVGVLAYILLSGQSPF 111
>16708
          Length = 1397

 Score = 56.6 bits (135), Expect = 6e-08,   Method: Compositional matrix adjust.
 Identities = 39/157 (24%), Positives = 75/157 (47%), Gaps = 5/157 (3%)
 Frame = -1

Query: 27   LVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTXXXXXXIKQEINMLKKYSHHRNIATYY 86
            +++V+G G +G+VY+ R + T + AA+K    T         E+  L +      +A  +
Sbjct: 1391 ILQVLGKGVFGKVYEARLLSTHEKAALK----TSILCHHSLDEVEALGRIEGGFYLAQMF 1224

Query: 87   GAFIKKSPPGNDDQLWLVMEFCGAGSVTDLVKNTKGNAL-----KEDCIAYICREILRGL 141
            GA++   P     ++ +++ F   G + ++  + K   +         +  I  + +  L
Sbjct: 1223 GAWVTCLP---FPKMNILLHFYEMGPLCNVYAHYKNKEMPIRWSNPAMVCCIAGQXVCAL 1053

Query: 142  AHLHAHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQL 178
             H+H   V+H D+K  NVL+  +   KL D+G+ AQL
Sbjct: 1052 EHIHELGVVHMDVKADNVLVDAHGNCKLTDYGI-AQL 945
>21210
          Length = 518

 Score = 56.6 bits (135), Expect = 6e-08,   Method: Compositional matrix adjust.
 Identities = 39/102 (38%), Positives = 53/102 (51%), Gaps = 5/102 (4%)
 Frame = +3

Query: 194 WMAPEVIACDENPDAT---YDYRSDIWSLGITAIEMAEGAPPLCD-MHPMRALFLIPRNP 249
           +MAPE I    +P A+   YD RSD+WSLGIT +E+A G  P    +     L  + R  
Sbjct: 18  YMAPERI----DPRASSHGYDVRSDVWSLGITLMELATGRFPYRKWVSIFDQLQQVVRGV 185

Query: 250 PPRL-KSKKWSKKFTDFIDTCLIKTYLSRPPTEQLLKFPFIR 290
            P L     +S  F +F++ CL K    RP   +LL  PF+R
Sbjct: 186 APCLPHDGAFSHDFVNFVNKCLTKDEKQRPKYNKLLAHPFVR 311
>07291
          Length = 833

 Score = 55.1 bits (131), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 33/112 (29%), Positives = 56/112 (50%), Gaps = 9/112 (8%)
 Frame = +1

Query: 135 REILRGLAHLHAHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQL--------DRTVGRRN 186
           R+I  G+A+L   KV+HR++  +N ++TE+  ++L D+GV+  L        D +  R  
Sbjct: 70  RQIADGMAYLQEVKVVHRNLAARNCIVTEDGRLQLSDYGVTGSLFPQSYYTADDSPAR-- 243

Query: 187 TFIGTPYWMAPEVIACDENPDATYDYRSDIWSLGITAIE-MAEGAPPLCDMH 237
                  WMAPE I      +  +  +SD+W+ G+   E +  G  P  D+ 
Sbjct: 244 ---DLVKWMAPETID-----NFHFSSKSDVWAFGVVLWELLTRGITPYPDVE 375
>03508
          Length = 1463

 Score = 54.3 bits (129), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 36/126 (28%), Positives = 61/126 (48%), Gaps = 5/126 (3%)
 Frame = +1

Query: 113 VTDLVKNTKGNALKEDCIAYICR----EILRGLAHLHAHKVIHRDIKGQNVLLT-ENAEV 167
           + + V NT    L +    Y  R    E+++ L   H+  ++HRD+K  NV++  EN ++
Sbjct: 814 IFEHVNNTDFKQLYQTFTDYDIRFYLYELMKALDFCHSMGIMHRDVKPHNVMIDHENKKL 993

Query: 168 KLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDATYDYRSDIWSLGITAIEMA 227
           +L+D+G+ A+        N  + + Y+  PE++         YDY  D+WSLG     M 
Sbjct: 994 RLIDWGL-AEFYHPGMEYNVRVASRYFKGPELLL----DYQMYDYSLDMWSLGCMFASMI 1158

Query: 228 EGAPPL 233
               PL
Sbjct: 1159FRKEPL 1176
>04138
          Length = 800

 Score = 52.0 bits (123), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 30/102 (29%), Positives = 50/102 (49%), Gaps = 3/102 (2%)
 Frame = +1

Query: 133 ICREILRGLAHLHAHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTF---I 189
           IC      L ++H +K++HRD+K  N+L+T+   +KL DFG++      + + N +   +
Sbjct: 28  IC*AADERLYYIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRV 207

Query: 190 GTPYWMAPEVIACDENPDATYDYRSDIWSLGITAIEMAEGAP 231
            T ++  PE++  D N    Y    D W  G    EM    P
Sbjct: 208 VTLWYRPPELLLGDRN----YSTAIDQWGAGCIMAEMWTRNP 321
>07836
          Length = 1478

 Score = 51.2 bits (121), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 46/167 (27%), Positives = 80/167 (47%), Gaps = 18/167 (10%)
 Frame = -1

Query: 79   HRNIATYYGAFIKKSPPGNDDQLWLVMEFCGAGSVTDLVKNTKGNALKEDCIAY--ICRE 136
            H NI  +  A IK +  G+  QL+L+ ++   GS+ D + +   ++ +   +A+  IC  
Sbjct: 1388 HENILGFIAADIKGT--GSWTQLFLITDYHENGSLHDYLLSRVLDSSEMLALAHSAIC-- 1221

Query: 137  ILRGLAHLHAH--------KVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTF 188
               GLAHLH           + HRDIK +N+L+ +N    + D G++    R +   N  
Sbjct: 1220 ---GLAHLHIEIFGTRGKPAIAHRDIKSKNILVKKNGTCCIADLGLAV---RYISESNEV 1059

Query: 189  -------IGTPYWMAPEVIACDENPDATYDYR-SDIWSLGITAIEMA 227
                    GT  +MAPEV+    N      ++ +D+++ G+   E+A
Sbjct: 1058 DVAPNPRQGTKRYMAPEVLEMLLNVKNFDAFKQADMYAFGLVMWEIA 918
>14477
          Length = 493

 Score = 49.7 bits (117), Expect = 7e-06,   Method: Composition-based stats.
 Identities = 44/174 (25%), Positives = 77/174 (44%), Gaps = 6/174 (3%)
 Frame = -1

Query: 31  VGNGTYGQVYKG------RHVKTGQLAAIKVMDVTXXXXXXIKQEINMLKKYSHHRNIAT 84
           +G G +G V KG      R +    +  +K  D+       + +E  ++KK  H  +I  
Sbjct: 466 LGAGNFGSVMKGVCRLDDREIPVA-IKVLKNADLDPSVQSELIKEAEVMKKMDH-MHIVR 293

Query: 85  YYGAFIKKSPPGNDDQLWLVMEFCGAGSVTDLVKNTKGNALKEDCIAYICREILRGLAHL 144
             G           + + LV+E    G +   +   K   L    I  +  ++ +G+ +L
Sbjct: 292 LIGLC-------EGETMMLVLELAKLGPLNKFLPKNKHLPLWN--ILELMWQVSQGMEYL 140

Query: 145 HAHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPE 198
            A+K +HRD+  +N+LL +    K+ DFG+S    +T+ R N      Y+MA E
Sbjct: 139 EANKFVHRDLAARNILLCDEHFAKISDFGMS----KTLSRENN-----YYMAQE 5
>17300
          Length = 480

 Score = 48.9 bits (115), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 35/104 (33%), Positives = 50/104 (48%), Gaps = 5/104 (4%)
 Frame = +1

Query: 137 ILRGLAHLHAHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQL--DRTVGRRNTFIGT--P 192
           I  G+  L     +HRD+  +N+L+ E    K+ DFG+S ++  D T G   T  G    
Sbjct: 1   ISSGMGXLADMGYVHRDLAARNILVNEILVCKVADFGLSREIESDTTEGAYTTKGGKIPV 180

Query: 193 YWMAPEVIACDENPDATYDYRSDIWSLGITAIE-MAEGAPPLCD 235
            W APE IA  +   A     SD+WS G+   E M+ G  P  +
Sbjct: 181 RWTAPEAIAYRKFTSA-----SDVWSFGVVMWEVMSYGERPYWN 297
>27546
          Length = 426

 Score = 47.0 bits (110), Expect = 5e-05,   Method: Composition-based stats.
 Identities = 26/108 (24%), Positives = 56/108 (51%)
 Frame = -1

Query: 68  QEINMLKKYSHHRNIATYYGAFIKKSPPGNDDQLWLVMEFCGAGSVTDLVKNTKGNALKE 127
           +E+ +L +  H   I  +  + +++ P     ++++ M +   G +   +K T    + E
Sbjct: 333 RELEILTRLDHPNIIQIH--SILQRGP-----KIFIFMRYAEKGDMLSHIKKT--GPIDE 181

Query: 128 DCIAYICREILRGLAHLHAHKVIHRDIKGQNVLLTENAEVKLVDFGVS 175
                   ++ + L +LH+H + HRD+K +N+LL++   VK+ DFG +
Sbjct: 180 AQTKVWFFQMAKALQYLHSHDIAHRDLKCENILLSKRLNVKIADFGFA 37
>12672
          Length = 773

 Score = 45.4 bits (106), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 29/101 (28%), Positives = 47/101 (46%), Gaps = 4/101 (3%)
 Frame = +3

Query: 133 ICREILRGLAHLHAHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQL----DRTVGRRNTF 188
           I +    G+ +L+ +  +HRDIK  N+LL      K+ DF           +TV   +  
Sbjct: 6   IVKGTASGIQYLNDNGHVHRDIKTANILLDSEYTAKVGDFATVVSAPSGEGKTVQNASVV 185

Query: 189 IGTPYWMAPEVIACDENPDATYDYRSDIWSLGITAIEMAEG 229
           IGT  ++APE I  D +       + D +S G+  +E+  G
Sbjct: 186 IGTAAYLAPEAIHFDVST------KLDSYSFGVVLLEVITG 290
>11404
          Length = 563

 Score = 41.2 bits (95), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 34/143 (23%), Positives = 64/143 (44%), Gaps = 2/143 (1%)
 Frame = +1

Query: 22  AGIFELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTXXXXXXIKQEINMLKKYSHHRN 81
           A  +E+  ++G G++GQV K       +  AIK++          + E+ +L+  + H  
Sbjct: 136 ADRYEIDSLIGKGSFGQVVKAYDHTDNEQVAIKIIKNKKPFLNQAQIEVKLLEMMNRHDT 315

Query: 82  IATYYGAFIKKSPPGNDDQLWLVMEFCGAGSVTDLVKNTKGNALKEDCIAYICREILRGL 141
              YY   +K+        L LV E   + ++ DL++NT    +  +      +++   L
Sbjct: 316 DNKYYIVRLKRHFMFR-SHLCLVFELL-SYNLYDLLRNTNFRGVSLNLTRKFAQQLCTAL 489

Query: 142 AHLHA--HKVIHRDIKGQNVLLT 162
             L      +IH D+K +N+LL 
Sbjct: 490 LFLATPEMSIIHCDLKPENILLC 558
>25019
          Length = 730

 Score = 40.8 bits (94), Expect = 0.003,   Method: Composition-based stats.
 Identities = 24/65 (36%), Positives = 34/65 (52%)
 Frame = +3

Query: 156 GQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDATYDYRSD 215
            +NVLL ++  VKL DFG+  +        +TF GT  +MAPE++    +  A      D
Sbjct: 258 AENVLLDKDGHVKLTDFGLCKEAITGTRVTHTFCGTIEYMAPEILTRTGHGKAV-----D 422

Query: 216 IWSLG 220
            WSLG
Sbjct: 423 WWSLG 437
>07833
          Length = 1504

 Score = 40.8 bits (94), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 33/145 (22%), Positives = 64/145 (44%), Gaps = 4/145 (2%)
 Frame = -3

Query: 101  LWLVMEFCGAGSVTDLVKNTKGNALKEDCIAYICREILRGLAHLHAHK--VIHRDIKGQN 158
            L L+ +F   GS+ + +    G  + ++       +I RG+  LH+ +  + +  +  ++
Sbjct: 1394 LVLISQFMPFGSLYNTLHGESGIVVDQNQSLRFAMDIARGMEFLHSMEPTIPNFLLTSKH 1215

Query: 159  VLLTEN--AEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDATYDYRSDI 216
            V++ E+  A + + D+  S       G+    + +P WMAPE  A    PD      +D+
Sbjct: 1214 VMIDEDLTARINMADYCFSFH---EKGK----VYSPAWMAPE--ALQRRPDDINTRAADM 1062

Query: 217  WSLGITAIEMAEGAPPLCDMHPMRA 241
            WS  I   E+     P  ++  M  
Sbjct: 1061 WSFAILMWELETREVPFAELSSMEV 987
>11185
          Length = 473

 Score = 40.8 bits (94), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 29/116 (25%), Positives = 49/116 (42%), Gaps = 22/116 (18%)
 Frame = +1

Query: 137 ILRGLAHLHAHKVIHRDIKGQNVLLTENAEVKLVDFGVS--------------------- 175
           ++ GL ++H+  ++  D++   VLL  +  +K  DFG+S                     
Sbjct: 28  LVTGLHYIHSLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEAGDQW 207

Query: 176 -AQLDRTVGRRNTFIGTPYWMAPEVIACDENPDATYDYRSDIWSLGITAIEMAEGA 230
             Q    + ++    G+P +MAPEV    E         SD+W+LG    EM  G+
Sbjct: 208 NIQSAEEMMKQVPTSGSPTYMAPEVFQGAEP-----SIMSDLWALGCVFYEMFSGS 360
>31489
          Length = 329

 Score = 40.4 bits (93), Expect = 0.005,   Method: Composition-based stats.
 Identities = 17/36 (47%), Positives = 25/36 (69%)
 Frame = +3

Query: 125 LKEDCIAYICREILRGLAHLHAHKVIHRDIKGQNVL 160
           L E+ I Y   +ILRGL ++H+  V+HRD+K  N+L
Sbjct: 156 LTEEHIRYFLYQILRGLKYIHSANVVHRDLKPSNLL 263
>18996
          Length = 491

 Score = 40.0 bits (92), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 27/83 (32%), Positives = 41/83 (49%), Gaps = 6/83 (7%)
 Frame = +2

Query: 150 IHRDIKGQNVLLTENAEVKLVDFGVSAQLDRT------VGRRNTFIGTPYWMAPEVIACD 203
           IHRD+  +N+L+  +  VK+ DFG+ AQ          + +R+  I    W +PE I   
Sbjct: 2   IHRDLAARNILVDRSC-VKISDFGL-AQFANADGYYYGISQRDIPIK---WYSPEAIE-- 160

Query: 204 ENPDATYDYRSDIWSLGITAIEM 226
                 +   SD+WS G+T  EM
Sbjct: 161 ---TCKFSSYSDVWSYGVTLFEM 220
>28157
          Length = 400

 Score = 40.0 bits (92), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 34/117 (29%), Positives = 59/117 (50%), Gaps = 6/117 (5%)
 Frame = +3

Query: 68  QEINMLKKYSHHRNIATYYGAFIKKSPPGNDDQLWLVMEFCGAGSVTDLVKNT--KGNAL 125
           QE+  L + SH  NI   YGA         D  + LVME+   GS+ +++  +  +    
Sbjct: 57  QELKQLSRVSH-PNIVCLYGAC-------RDHPVCLVMEYAEGGSLYNVLHGSGPQPQYT 212

Query: 126 KEDCIAYICREILRGLAHLHAHK---VIHRDIKGQNVLLTE-NAEVKLVDFGVSAQL 178
               + ++ +  L G+ +LH  K   +IHRD+K  N+LL +   ++K+ DFG +  +
Sbjct: 213 AAHAMNWLLQCAL-GVEYLHGMKPKALIHRDLKPPNLLLIQCGTKLKICDFGTACDI 380
>20640
          Length = 1492

 Score = 39.3 bits (90), Expect = 0.012,   Method: Compositional matrix adjust.
 Identities = 25/87 (28%), Positives = 43/87 (49%), Gaps = 6/87 (6%)
 Frame = +1

Query: 150 IHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPY------WMAPEVIACD 203
           +HRD+  +N L+  +  VK+ DFG    L R+V   + + G+ +      WM  E I  +
Sbjct: 10  VHRDLATRNCLVGHDLVVKISDFG----LARSVHSVDYYRGSEHDAIPIRWMPLEAILYN 177

Query: 204 ENPDATYDYRSDIWSLGITAIEMAEGA 230
           +     +  +SD+WS G+   E+   A
Sbjct: 178 K-----FSTQSDVWSFGVVLWEIFAFA 243
>37063
          Length = 455

 Score = 38.5 bits (88), Expect = 0.016,   Method: Composition-based stats.
 Identities = 27/76 (35%), Positives = 40/76 (52%), Gaps = 8/76 (10%)
 Frame = -2

Query: 154 IKGQNVL---LTENAEVKLVDF----GVSAQLDRT-VGRRNTFIGTPYWMAPEVIACDEN 205
           +K +N+L   L E   +K+ DF    G++   D T      T +G+  +MAPEV+     
Sbjct: 454 LKPENILCEHLDEVVPLKICDFDLASGINCDGDGTKTPELLTPVGSAEYMAPEVVDAWVG 275

Query: 206 PDATYDYRSDIWSLGI 221
              +YD R D+WSLGI
Sbjct: 274 ESFSYDKRCDMWSLGI 227
>24241
          Length = 413

 Score = 38.1 bits (87), Expect = 0.021,   Method: Composition-based stats.
 Identities = 25/80 (31%), Positives = 40/80 (50%), Gaps = 3/80 (3%)
 Frame = -2

Query: 31  VGNGTYGQVYKGRHVKTGQLAAIKVMDVTXXXX---XXIKQEINMLKKYSHHRNIATYYG 87
           +G GTYG VYK RH  TG+  A+K + +            +EI ML++  H + +     
Sbjct: 319 IGEGTYGVVYKCRHRATGRKLAMKKIRLRGSEDGVPSSAIREIAMLRELRHTQXLVCLED 140

Query: 88  AFIKKSPPGNDDQLWLVMEF 107
             ++      D++L+LV EF
Sbjct: 139 VIME------DERLFLVFEF 98
>18663
          Length = 600

 Score = 37.4 bits (85), Expect = 0.043,   Method: Compositional matrix adjust.
 Identities = 17/48 (35%), Positives = 27/48 (56%)
 Frame = +2

Query: 186 NTFIGTPYWMAPEVIACDENPDATYDYRSDIWSLGITAIEMAEGAPPL 233
           +TF GTP ++APE++  ++     Y +  D W+LG+   EM  G  P 
Sbjct: 2   STFCGTPNYIAPEILRGED-----YGFSVDWWALGVLLYEMLAGRSPF 130
>32359
          Length = 928

 Score = 37.0 bits (84), Expect = 0.058,   Method: Compositional matrix adjust.
 Identities = 34/142 (23%), Positives = 62/142 (43%), Gaps = 3/142 (2%)
 Frame = -1

Query: 29  EVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTXXXXXXIKQEINMLKKYSHHRNIATYYGA 88
           +V+GNG++G VY+ + V T +L AIK +           +E+ +++K   H+NI      
Sbjct: 412 KVIGNGSFGVVYQAKLVDTSELVAIKKV---LQDKRFKNRELQIMRKLE-HQNIVKLKFF 245

Query: 89  FIKKSPPGNDDQLWLVMEFCGAGSVTDLVKNTKGNALKEDCIAYI---CREILRGLAHLH 145
           F       ++  L LV+E+         V      + +   I YI     ++ R LA++H
Sbjct: 244 FYSSGEKKDEVFLNLVLEY--VPETVYRVARHYSKSKQTIPILYIKLYMYQLFRSLAYIH 71

Query: 146 AHKVIHRDIKGQNVLLTENAEV 167
           +   +      +   LT+  E 
Sbjct: 70  SQACVTATSSLKTCCLTQRLEC 5
>36481
          Length = 806

 Score = 37.0 bits (84), Expect = 0.059,   Method: Compositional matrix adjust.
 Identities = 31/134 (23%), Positives = 61/134 (45%), Gaps = 1/134 (0%)
 Frame = +2

Query: 32  GNGTYGQVYKGRHVKTGQLAAIKVMDVTXXXXXXIKQEINMLKKYSHHRNIATYYGAFIK 91
           G GT+G+V + + +  G   A+K++          K EIN+L+K    R    +      
Sbjct: 389 GEGTFGKVVQCKDLLKGDDIALKIIKNVDKYREAAKLEINVLEKL---REKDPHAKHMCV 559

Query: 92  KSPPGNDDQLWLVMEFCGAG-SVTDLVKNTKGNALKEDCIAYICREILRGLAHLHAHKVI 150
           +     D    + + F   G SV D +K+    A   + + +I  ++   +  LH +++ 
Sbjct: 560 QMLDWFDYHGHVCISFHMLGLSVFDFLKDNSYGAYPIEQVRHISYQLCYAVNFLHENQLT 739

Query: 151 HRDIKGQNVLLTEN 164
           H D+K +N+L  ++
Sbjct: 740 HTDLKPENILFVDS 781
>02638
          Length = 1490

 Score = 36.6 bits (83), Expect = 0.064,   Method: Compositional matrix adjust.
 Identities = 32/107 (29%), Positives = 44/107 (41%), Gaps = 5/107 (4%)
 Frame = +1

Query: 188 FIGTPYWMAPEVIACDENPDATYDYRSDIWSLGITAIEMAEGAPPLCDMHPMRALFLIPR 247
            +GT  +MAPEV+        +Y    D+WS+G   IEM    PP         L LI +
Sbjct: 16  LLGTIAFMAPEVLR-----GESYGRACDVWSVGCVMIEMCTCRPPWNSHDISNHLALIFK 180

Query: 248 -----NPPPRLKSKKWSKKFTDFIDTCLIKTYLSRPPTEQLLKFPFI 289
                +PPP    +  S    D +  CL +    RP  + LL  P  
Sbjct: 181 IASSVDPPP--IPENMSPPVRDLMLRCLEQDSDFRPSAKDLLMHPLF 315
>01106
          Length = 878

 Score = 35.4 bits (80), Expect = 0.16,   Method: Compositional matrix adjust.
 Identities = 31/147 (21%), Positives = 64/147 (43%), Gaps = 7/147 (4%)
 Frame = +3

Query: 23  GIFELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTXXXXXXIKQEINMLKKYSHHRNI 82
           G + ++  +G G +  V+    +   +  A+KV+            E+ +LK        
Sbjct: 318 GRYHVIRKLGWGHFSTVWLCWDLTCKRFVALKVVKSAQHYTETALDEVKLLKCVRESDVA 497

Query: 83  ATYYGAFIK-----KSPPGNDDQLWLVMEFCGAGSVTDLVK-NTKGNALKEDCIAYICRE 136
                  ++     K    N   + +V E  G   +  +++ N +G  +    +  I R+
Sbjct: 498 DPARAKCVQLLDDFKISGVNGTHVAMVFEVLGYNLLKLIIRSNYQGIPIHN--VKLIIRQ 671

Query: 137 ILRGLAHLHAH-KVIHRDIKGQNVLLT 162
           +L GL+++HA  ++IH DIK +N+L+ 
Sbjct: 672 VLEGLSYMHAKCRIIHTDIKPENILIC 752
>00486
          Length = 797

 Score = 35.4 bits (80), Expect = 0.16,   Method: Compositional matrix adjust.
 Identities = 30/101 (29%), Positives = 45/101 (44%), Gaps = 3/101 (2%)
 Frame = -2

Query: 186 NTFIGTPYWMAPEVIACDENPDATYDYRSDIWSLGITAIEMAEGAPPLCDMHPMRALFLI 245
           +TF GT  +MAPE++    +  A      D WSLG    +M  G+PP    +  + +  I
Sbjct: 784 HTFCGTIEYMAPEILTRTGHGKAV-----DWWSLGALMYDMLTGSPPFTAENRKKTIDKI 620

Query: 246 PR---NPPPRLKSKKWSKKFTDFIDTCLIKTYLSRPPTEQL 283
            +   N PP L ++             LIK  L + P E+L
Sbjct: 619 LKGKLNLPPYLTNEA----------RGLIKKLLRKNPAERL 527
>32691
          Length = 295

 Score = 34.7 bits (78), Expect = 0.28,   Method: Composition-based stats.
 Identities = 14/34 (41%), Positives = 20/34 (58%)
 Frame = +1

Query: 257 KWSKKFTDFIDTCLIKTYLSRPPTEQLLKFPFIR 290
           KWS +F DF+  CL+K   +R     LL+  FI+
Sbjct: 82  KWSTEFIDFVSKCLVKNPENRATAVDLLQHDFIK 183
>28865
          Length = 342

 Score = 34.3 bits (77), Expect = 0.34,   Method: Compositional matrix adjust.
 Identities = 18/51 (35%), Positives = 29/51 (56%), Gaps = 3/51 (5%)
 Frame = -3

Query: 29  EVVGNGTYGQVYKGRHVKTGQLAAIKVMD---VTXXXXXXIKQEINMLKKY 76
           +V+G+G +G VY G H +T +  AIKV+D           +K E+ +L+ Y
Sbjct: 184 DVLGSGQFGIVYGGCHRRTNREVAIKVIDKLRFPTKQEAQLKTEVAILQNY 32
>18481
          Length = 437

 Score = 34.3 bits (77), Expect = 0.36,   Method: Composition-based stats.
 Identities = 35/148 (23%), Positives = 61/148 (41%), Gaps = 3/148 (2%)
 Frame = -1

Query: 39  VYKGRHVKTGQLAAIKVMDVTXXXXXXIKQEINMLKKYSHHRNIATYYGAFIKKSPPGND 98
           +Y+G + + G+  A+K+ +        +  E  + ++   H  + T Y    +K      
Sbjct: 437 IYQGYNTQDGKDIAVKI-EAIDVKHQLLHYEAKVYEQIGRHPGLPTMYHYGTEKHFNA-- 267

Query: 99  DQLWLVMEFCGAGSVTDLVKNTKGNALKEDCIAYICREILRGLAHLHAHKVIHRDIKGQN 158
               LVME  G       V   +   LK   I  +  ++L  L  +H    IHRD+K  N
Sbjct: 266 ----LVMELLGPSLEELFVICKRRFTLKT--ILMVSDQLLSRLEFIHQKCFIHRDLKPDN 105

Query: 159 VLL---TENAEVKLVDFGVSAQLDRTVG 183
            L+        + ++DFG+S +   T G
Sbjct: 104 FLMGLGRHCHRLYIIDFGLSKRYKDTQG 21
>17516
          Length = 453

 Score = 33.9 bits (76), Expect = 0.47,   Method: Composition-based stats.
 Identities = 17/43 (39%), Positives = 24/43 (55%)
 Frame = -3

Query: 187 TFIGTPYWMAPEVIACDENPDATYDYRSDIWSLGITAIEMAEG 229
           T  GTP +MAPEV+         YD ++D++SL I   E+  G
Sbjct: 442 TLAGTPVYMAPEVLL----QKGQYDMKADVYSLAIILWELWYG 326
>26156
          Length = 479

 Score = 33.5 bits (75), Expect = 0.62,   Method: Composition-based stats.
 Identities = 23/90 (25%), Positives = 45/90 (50%), Gaps = 1/90 (1%)
 Frame = -1

Query: 25  FELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTXXXXXXIKQEINMLKKYSHHRNIAT 84
           F L+ V+G G+Y +V +  H +T ++ A+KV+           ++I+ ++   H    AT
Sbjct: 383 FLLLRVIGRGSYAKVLQVEHKRTKRIYAMKVIKKELVND---DEDIDWVQTEKHVFETAT 213

Query: 85  YYGAFIK-KSPPGNDDQLWLVMEFCGAGSV 113
            Y   +   S   ++ +L+ V+EF   G +
Sbjct: 212 NYPFLVGLHSCFQSESRLFFVIEFVNGGDL 123
>15741
          Length = 402

 Score = 33.5 bits (75), Expect = 0.64,   Method: Composition-based stats.
 Identities = 11/24 (45%), Positives = 19/24 (79%)
 Frame = -3

Query: 137 ILRGLAHLHAHKVIHRDIKGQNVL 160
           + RG+AH+  +K++HRD+  +NVL
Sbjct: 73  VARGMAHVANNKIVHRDVAARNVL 2
>29590
          Length = 320

 Score = 33.1 bits (74), Expect = 0.76,   Method: Composition-based stats.
 Identities = 17/45 (37%), Positives = 25/45 (55%)
 Frame = +3

Query: 189 IGTPYWMAPEVIACDENPDATYDYRSDIWSLGITAIEMAEGAPPL 233
           IGTP ++APEV+  D  P      ++D+WSLG+ +  M     P 
Sbjct: 57  IGTPDYVAPEVL--DYEP---LSIQTDMWSLGVLSYVMLTACSPF 176
>21800
          Length = 855

 Score = 33.1 bits (74), Expect = 0.81,   Method: Compositional matrix adjust.
 Identities = 15/34 (44%), Positives = 23/34 (67%), Gaps = 1/34 (2%)
 Frame = +2

Query: 130 IAYICREILRGLAHLHAH-KVIHRDIKGQNVLLT 162
           +  I R++L GL +LHA   +IH DIK +N+L+ 
Sbjct: 638 VKLIIRQVLEGLNYLHAKCNIIHTDIKPENILIC 739
>22005
          Length = 873

 Score = 33.1 bits (74), Expect = 0.82,   Method: Compositional matrix adjust.
 Identities = 28/111 (25%), Positives = 50/111 (45%), Gaps = 6/111 (5%)
 Frame = +1

Query: 132 YICREILRGLAHLHAHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGT 191
           YI ++I  G+A+L     +HRD+     + +      + DFG++    R+V   + + G+
Sbjct: 454 YISQQISAGMAYLAQKDYVHRDL-ATRTVXSRTT*S*ISDFGLA----RSVHSVDYYRGS 618

Query: 192 PY------WMAPEVIACDENPDATYDYRSDIWSLGITAIEMAEGAPPLCDM 236
                   WM  E I       + +  +SD+WS G+   E+    P LC +
Sbjct: 619 EQDAIPIRWMPLEAILY-----SKFSTQSDVWSFGVVLWEI---LPLLCSL 747
>32000
          Length = 644

 Score = 32.0 bits (71), Expect = 1.8,   Method: Compositional matrix adjust.
 Identities = 20/64 (31%), Positives = 31/64 (48%), Gaps = 1/64 (1%)
 Frame = -1

Query: 164 NAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVI-ACDENPDATYDYRSDIWSLGIT 222
            A++K+ DFG++      V      + T ++ APE++  C       Y    DIWSLG  
Sbjct: 581 TAKMKIADFGLARVFGLPVRTYTHEVITLWYRAPEILLGC-----RFYSVPVDIWSLGCI 417

Query: 223 AIEM 226
            +EM
Sbjct: 416 FVEM 405
>26009
          Length = 886

 Score = 31.6 bits (70), Expect = 2.4,   Method: Compositional matrix adjust.
 Identities = 10/29 (34%), Positives = 22/29 (75%)
 Frame = +3

Query: 133 ICREILRGLAHLHAHKVIHRDIKGQNVLL 161
           + ++++  L  +H+ +++HRDIK +NVL+
Sbjct: 726 VMKQLVSALDFMHSKQLVHRDIKPENVLI 812
>21727
          Length = 366

 Score = 30.4 bits (67), Expect = 4.7,   Method: Composition-based stats.
 Identities = 12/49 (24%), Positives = 26/49 (53%), Gaps = 2/49 (4%)
 Frame = -3

Query: 78  HHRNIATYY--GAFIKKSPPGNDDQLWLVMEFCGAGSVTDLVKNTKGNA 124
           H+ N+ +++   A+ +     N  Q+W + EF    ++ +++KN  G A
Sbjct: 190 HNSNVCSFFMGKAYSRSKHQENKQQIWQIYEFTITNNLKNIIKNKNGKA 44
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|12025532|ref|NP_058616.1| ATPase, H+ transporting,
lysosomal V0 subunit a1 [Mus musculus]
         (838 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

07897                                                                 370   e-148
28221                                                                 174   1e-77
30032                                                                 102   5e-22
32691                                                                  32   0.79 
09801                                                                  29   6.6  
>07897
          Length = 1376

 Score =  370 bits (949), Expect(2) = e-148,   Method: Compositional matrix adjust.
 Identities = 173/281 (61%), Positives = 217/281 (77%)
 Frame = +2

Query: 166 LRLGFVAGVINRERIPTFERMLWRVCRGNVFLRQAEIENPLEDPVTGDYVHKSVFIIFFQ 225
           ++LGFVAGVI RE++P FER+LW  CRGNVFLR   IE  LEDP++G+ V K VF+IF+Q
Sbjct: 77  IQLGFVAGVIPREKVPAFERLLWFACRGNVFLRHEPIEYALEDPMSGNPVLKDVFVIFYQ 256

Query: 226 GDQLKNRVKKICEGFRASLYPCPETPQERKEMASGVNTRIDDLQMVLNQTEDHRQRVLQA 285
           G+QLKN+VKKICEGF+AS+YPCPET +ER++M  GV TR+ DL +V+NQT DHR RVL  
Sbjct: 257 GEQLKNKVKKICEGFKASVYPCPETFEEREDMLKGVVTRLADLAIVMNQTADHRYRVLVG 436

Query: 286 AAKNIRVWFIKVRKMKAIYHTLNLCNIDVTQKCLIAEVWCPVTDLDSIQFALRRGTEHSG 345
           A K++R W IKV K+KAIYHTLN+ N D++   LIAE WCP + LD +  ALR G   SG
Sbjct: 437 AQKDMRSWMIKVEKIKAIYHTLNMFNFDMSHNSLIAECWCPRSALDKVYTALRSGEMASG 616

Query: 346 STVPSILNRMQTNQTPPTYNKTNKFTHGFQNIVDAYGIGTYREINPAPYTVITFPFLFAV 405
           STVPSI+  M+T + PPTY +TNKFT GFQNIV+AYGI TYRE+NPA YT ITFPFLFA+
Sbjct: 617 STVPSIIQTMETTKKPPTYFQTNKFTSGFQNIVNAYGIATYREVNPALYTCITFPFLFAI 796

Query: 406 MFGDFGHGILMTLFAVWMVLRESRILSQKHENEMFSMVFSG 446
           MFGD GHG++M LF +WM+  E     ++ +NE+ +  FSG
Sbjct: 797 MFGDAGHGLIMALFGMWMIYSERSF--KRSDNEI-ANTFSG 910

 Score =  173 bits (438), Expect(2) = e-148,   Method: Compositional matrix adjust.
 Identities = 90/163 (55%), Positives = 112/163 (68%), Gaps = 2/163 (1%)
 Frame = +1

Query: 444  FSGRYIILLMGLFSIYTGLIYNDCFSKSLNIFGSSWSVRPMFTQGNWT--EETLLGSSVL 501
            F GRYII LMGLFSIYTGLIYND +SKSLNIFGS+W +     + N T  E+  L     
Sbjct: 904  FGGRYIITLMGLFSIYTGLIYNDVYSKSLNIFGSAWRMGDYDLKPNATYPEQFTLDPLYF 1083

Query: 502  QLNPAIPGVFGGPYPFGIDPIWNIATNKLTFLNSFKMKMSVILGIIHMLFGVSLSLFNHI 561
              N         PYPFG+DP+W  + NK+ FLNS KMK++VI+GI  M+FG+ LSLFNH+
Sbjct: 1084 YRNHT-------PYPFGVDPVWQASKNKIAFLNSLKMKLAVIIGISQMMFGICLSLFNHL 1242

Query: 562  YFKKPLNIYFGFIPEIIFMSSLFGYLVILIFYKWTAYDAHSSR 604
            +F++ LNI+  FIPE+IF+  LFGYLV LIFYKW  Y+   S 
Sbjct: 1243 HFRRYLNIFVEFIPEVIFLGCLFGYLVGLIFYKWVYYEPQDSE 1371
>28221
          Length = 1258

 Score =  174 bits (440), Expect(3) = 1e-77,   Method: Compositional matrix adjust.
 Identities = 100/223 (44%), Positives = 131/223 (58%), Gaps = 17/223 (7%)
 Frame = -2

Query: 628 MLYSGQKGIQCFLIVVAMLCVPWMLLFKPLILRHQYLRKKHLGTLNFGGIR-----VGNG 682
           ++Y  QKG+Q  L+ +A+L VP +LLFKPL L++Q   K    T+   G R     + N 
Sbjct: 711 IIYDSQKGVQMALLAMALLSVPVLLLFKPLYLKYQNRLKV---TVQLQGSRATDALIANE 541

Query: 683 PTEEDAEIIQHDQLSTHSEDAEEPTED--------EVFDFGDTMVHQAIHTIEYCLGCIS 734
            T +   +  +  +++  E+A+  T +        E FDFG+  +HQAIHTIE+CLGCIS
Sbjct: 540 GTADSDTMPPNRSVNSEDEEAQAGTTNIFLLVEEEEEFDFGEIFIHQAIHTIEFCLGCIS 361

Query: 735 NTASYLRLWALSLAHAQLSEVLWTMVIHIGLHVR----SXXXXXXXXXXXXXXXXXXXXX 790
           +TASYLRLWALSLAHAQLSEVLW+MV+ +GL +                           
Sbjct: 360 HTASYLRLWALSLAHAQLSEVLWSMVLSLGLKMELSFFPSLGALPIFALWFFWANLTIAI 181

Query: 791 XXXMEGLSAFLHALRLHWVEFQNKFYTGTGFKFLPFSFEHIRE 833
              MEGLSAFLH LRLHWVEFQ+KFY G G  F PF+F  I +
Sbjct: 180 LLLMEGLSAFLHTLRLHWVEFQSKFYEGDGVLFNPFTFNDILQ 52

 Score =  126 bits (317), Expect(3) = 1e-77,   Method: Compositional matrix adjust.
 Identities = 55/94 (58%), Positives = 72/94 (76%)
 Frame = -1

Query: 514  PYPFGIDPIWNIATNKLTFLNSFKMKMSVILGIIHMLFGVSLSLFNHIYFKKPLNIYFGF 573
            PYPFG+DP+W  + NK+ FLNS KMK++VI+GI  M+FG+ LSLFNH++F++ LNI+  F
Sbjct: 1102 PYPFGVDPVWQASKNKIAFLNSLKMKLAVIIGISQMMFGICLSLFNHLHFRRYLNIFVEF 923

Query: 574  IPEIIFMSSLFGYLVILIFYKWTAYDAHSSRNAP 607
            IPE+IF+  LFGYLV LIFYKW  Y+    R  P
Sbjct: 922  IPEVIFLGCLFGYLVGLIFYKWVYYEPPRLRVCP 821

 Score = 30.4 bits (67), Expect(3) = 1e-77,   Method: Compositional matrix adjust.
 Identities = 12/22 (54%), Positives = 16/22 (72%)
 Frame = -3

Query: 606 APSLLIHFINMFLFSYPESGNA 627
            P+LLIH+INMF+ +Y E  N 
Sbjct: 824 PPALLIHYINMFMMTYNERPNG 759
>30032
          Length = 469

 Score =  102 bits (255), Expect = 5e-22,   Method: Composition-based stats.
 Identities = 54/115 (46%), Positives = 69/115 (60%), Gaps = 4/115 (3%)
 Frame = +2

Query: 646 LCVPWMLLFKPLILRHQYLRKKHLGTLNFGGIRVGNGPTEEDAEIIQHDQLSTHSEDAEE 705
           +CVPWM+ FKP  +RHQ       G      + V +G      +++ HDQ   H+ D   
Sbjct: 2   MCVPWMMFFKPFYMRHQ----ARFGQFKHQPLSVQSG------DLLNHDQEVVHNNDTAR 151

Query: 706 PTEDE----VFDFGDTMVHQAIHTIEYCLGCISNTASYLRLWALSLAHAQLSEVL 756
           P  +E     FDF +  VHQ +HTIE+CLGCIS+TASYLRLWALSLAHA+ S V 
Sbjct: 152 PPPEEEEQEAFDFSEVFVHQVVHTIEFCLGCISHTASYLRLWALSLAHARKSGVF 316
>32691
          Length = 295

 Score = 32.3 bits (72), Expect = 0.79,   Method: Composition-based stats.
 Identities = 15/43 (34%), Positives = 24/43 (55%)
 Frame = +1

Query: 44  VNVFQRKFVNEVRRCEEMDRKLRFVEKEIRKANIPIMDTGENP 86
           V++ Q  F+ +   CE +   +R   KEI++  + IM  GENP
Sbjct: 154 VDLLQHDFIKKAEACEILQAMIR-EAKEIQEMQMQIMSNGENP 279
>09801
          Length = 1599

 Score = 29.3 bits (64), Expect = 6.6,   Method: Composition-based stats.
 Identities = 13/37 (35%), Positives = 21/37 (56%)
 Frame = -2

Query: 244  LYPCPETPQERKEMASGVNTRIDDLQMVLNQTEDHRQ 280
            ++PC E    RK+ +S +NT   DL  +L   + HR+
Sbjct: 1595 IFPCKEQAYSRKDGSSSINTASLDLFSLLGVDDIHRK 1485
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|157951741|ref|NP_033934.2| catalase [Mus musculus]
         (527 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

13683                                                                 517   e-147
07434                                                                 207   3e-71
21138                                                                  48   8e-06
12141                                                                  33   0.24 
33005                                                                  28   7.9  
>13683
          Length = 1237

 Score =  517 bits (1331), Expect = e-147,   Method: Compositional matrix adjust.
 Identities = 242/353 (68%), Positives = 289/353 (81%)
 Frame = +1

Query: 32  GNPIGDKLNIMTAGSRGPLLVQDVVFTDEMAHFDRERIPERVVHAKGAGAFGYFEVTHDI 91
           G P+G+KL  +T G RGP+L+QD VFTDEMAHF+RERIPERVVHAKG+GAFGYFEVTHDI
Sbjct: 4   GCPVGNKLASLTVGPRGPILLQDFVFTDEMAHFNRERIPERVVHAKGSGAFGYFEVTHDI 183

Query: 92  TRYSKAKVFEHIGKRTPIAVRFSTVTGESGSADTVRDPRGFAVKFYTEDGNWDLVGNNTP 151
           T+Y KAK+F  +GK+TP+AVRFSTV GE GSADT RDPRGFAVKFYTE+GNWDLVGNNTP
Sbjct: 184 TKYCKAKIFSKVGKKTPLAVRFSTVGGEKGSADTARDPRGFAVKFYTEEGNWDLVGNNTP 363

Query: 152 IFFIRDAILFPSFIHSQKRNPQTHLKDPDMVWDFWSLRPESLHQVSFLFSDRGIPDGHRH 211
           IFFIRD ILFPSFIH+QKRNP T+LKD DM WDF SLRPE+ HQVSFLFSDRG PDG+RH
Sbjct: 364 IFFIRDPILFPSFIHTQKRNPATNLKDXDMFWDFISLRPETTHQVSFLFSDRGTPDGYRH 543

Query: 212 MNGYGSHTFKLVNADGEAVYCKFHYKTDQGIKNLPVGEAGRLAQEDPDYGLRDLFNAIAN 271
           MNGYGSHTFKLVN   +AVYCKFH+KTDQGIKN+   +AG ++  DPDY  RDL+NAIA+
Sbjct: 544 MNGYGSHTFKLVNDKNQAVYCKFHFKTDQGIKNMMADKAGEISGTDPDYAQRDLYNAIAD 723

Query: 272 GNYPSWTFYIQVMTFKEAETFPFNPFDLTKVWPHKDYPLIPVGKLVLNKNPVNYFAEVEQ 331
            ++PSWT +IQVMTF++AE + +NPFDLTKVWP  ++PLIPVGK+VL++NP NYFAEVEQ
Sbjct: 724 KHFPSWTLHIQVMTFQQAEKYRWNPFDLTKVWPQSEFPLIPVGKMVLDRNPKNYFAEVEQ 903

Query: 332 MAFDPSNMPPGIEPSPDKMLQGRLFAYPDTHRHRLGPNYLQIPVNCPYRARVA 384
           +AF P +M PG+EPS  K  +  + ++  TH    G  +     +CP  A + 
Sbjct: 904 IAFSPVHMVPGVEPSLTKCCR-VVCSHTQTH---TGIVWAATTCSCPSTAPIT 1050

 Score =  128 bits (321), Expect = 6e-30,   Method: Compositional matrix adjust.
 Identities = 58/88 (65%), Positives = 66/88 (75%)
 Frame = +3

Query: 347  PDKMLQGRLFAYPDTHRHRLGPNYLQIPVNCPYRARVANYQRDGPMCMHDNQGGAPNYYP 406
            PDKMLQGRLF+Y DTHRHRLG NYLQ+PVNCPY  +  NYQRDGP C+ DNQG APNYYP
Sbjct: 948  PDKMLQGRLFSYSDTHRHRLGSNYLQLPVNCPYNTKARNYQRDGPQCVDDNQGDAPNYYP 1127

Query: 407  NSFSAPEQQRSALEHSVQCAVDVKRFNS 434
            NSFS P      LE     + DV+R+N+
Sbjct: 1128 NSFSGPVDNVKHLECPAHVSGDVQRYNT 1211
>07434
          Length = 864

 Score =  207 bits (526), Expect(2) = 3e-71,   Method: Compositional matrix adjust.
 Identities = 98/173 (56%), Positives = 120/173 (69%), Gaps = 5/173 (2%)
 Frame = +3

Query: 342 GIEPSPDKMLQ-----GRLFAYPDTHRHRLGPNYLQIPVNCPYRARVANYQRDGPMCMHD 396
           G+EPSPDKMLQ     GRLF+Y DTHRHRLG NYLQ+PVNCPY  +  NYQRDGP C+ D
Sbjct: 150 GVEPSPDKMLQLWLLQGRLFSYSDTHRHRLGSNYLQLPVNCPYNTKARNYQRDGPQCVDD 329

Query: 397 NQGGAPNYYPNSFSAPEQQRSALEHSVQCAVDVKRFNSANEDNVTQVRTFYTKVLNEEER 456
           NQG APNYYPNSFS P      LE     + DV+R+N+A++DN TQ  TF+ KVL   ER
Sbjct: 330 NQGDAPNYYPNSFSGPVDNVKHLECPAHVSGDVQRYNTADDDNFTQTGTFWNKVLKVNER 509

Query: 457 KRLCENIAGHLKDAQLFIQKKAVKNFTDVHPDYGARIQALLDKYNAEKPKNAI 509
            RL ENIAGH+KDA+ FIQ++AV NF     ++G ++Q  LD Y  +   N +
Sbjct: 510 TRLVENIAGHMKDAKDFIQQRAVANFAKADAEFGKQLQKALDDYKKKTQTNGV 668

 Score = 80.5 bits (197), Expect(2) = 3e-71,   Method: Compositional matrix adjust.
 Identities = 35/49 (71%), Positives = 43/49 (87%)
 Frame = +2

Query: 294 FNPFDLTKVWPHKDYPLIPVGKLVLNKNPVNYFAEVEQMAFDPSNMPPG 342
           +NPFDLTKVWP  ++PLIPVGK+VL++NP NYFAEVEQ+AF P +M PG
Sbjct: 5   WNPFDLTKVWPQSEFPLIPVGKMVLDRNPKNYFAEVEQIAFSPVHMVPG 151
>21138
          Length = 388

 Score = 48.1 bits (113), Expect = 8e-06,   Method: Composition-based stats.
 Identities = 23/54 (42%), Positives = 35/54 (64%)
 Frame = +2

Query: 451 LNEEERKRLCENIAGHLKDAQLFIQKKAVKNFTDVHPDYGARIQALLDKYNAEK 504
           L+   +KRL +NIA +L +A  F+Q++AVKNFT VH D+G  +   L+   + K
Sbjct: 17  LDNCAKKRLVQNIADNLSNASQFLQERAVKNFTMVHADFGRMLTEALNLIKSAK 178
>12141
          Length = 935

 Score = 33.5 bits (75), Expect = 0.24,   Method: Compositional matrix adjust.
 Identities = 24/90 (26%), Positives = 41/90 (45%), Gaps = 2/90 (2%)
 Frame = -1

Query: 35  IGDKLNIMTAGSRGPL-LVQDVVFTDEMAHFDRERIP-ERVVHAKGAGAFGYFEVTHDIT 92
           +G    I+T G  G + L +     ++M +     +P ++VV   GAG      + H+  
Sbjct: 413 MGANTVILTMGKLGAVCLTKQARTVEDMIYEPAPHVPADKVVDTTGAGDAFIGALAHNFA 234

Query: 93  RYSKAKVFEHIGKRTPIAVRFSTVTGESGS 122
           RY + K+FEHI     +A +   + G   S
Sbjct: 233 RYPQQKLFEHIAAACVVASKSVQLPGTQAS 144
>33005
          Length = 786

 Score = 28.5 bits (62), Expect = 7.9,   Method: Compositional matrix adjust.
 Identities = 16/48 (33%), Positives = 26/48 (54%)
 Frame = -2

Query: 162 PSFIHSQKRNPQTHLKDPDMVWDFWSLRPESLHQVSFLFSDRGIPDGH 209
           P+ IHS   +PQT+   P ++    +  P+S+H +  L   +G P GH
Sbjct: 365 PTQIHS--VSPQTYKHTPSLIHPSHTNNPKSMHDILVLADRKGPPPGH 228
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|34610207|ref|NP_666329.2| alanyl-tRNA synthetase [Mus
musculus]
         (968 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

05919                                                                 520   e-147
33800                                                                  54   3e-07
17051                                                                  30   3.2  
13135                                                                  30   5.8  
32306                                                                  29   8.3  
>05919
          Length = 1196

 Score =  520 bits (1338), Expect = e-147,   Method: Compositional matrix adjust.
 Identities = 265/401 (66%), Positives = 315/401 (78%), Gaps = 1/401 (0%)
 Frame = -3

Query: 282  KVGAEDADGIDMAYRVLADHARTITVALADGGRPDNTGRGYVLRRILRRAVRYSHEKLNA 341
            +VG +D DGIDMAYRVLADHART+TVAL+DGGRPDN GRGYVLRR+LRRAVRY+ EKLNA
Sbjct: 1194 RVGKDDVDGIDMAYRVLADHARTLTVALSDGGRPDNAGRGYVLRRVLRRAVRYATEKLNA 1015

Query: 342  SRGFFATLVDVVVQSLGDAFPELKKDPEMVKDIINEEEVQFLKTLSRGRRILDRKIQSLG 401
              G FA+LVD VVQ LG+AFPE++KDPE VK+IINEEE QFLKTLSRG+++L R I  LG
Sbjct: 1014 KPGMFASLVDTVVQLLGEAFPEVRKDPETVKEIINEEEAQFLKTLSRGQKLLLRTISKLG 835

Query: 402  DCKTI-PGDTAWLLYDTYGFPVDLTGLIAEEKGLVVDMNGFEEERRLAQLKSQGKGAGDE 460
               ++ PGD AW LYDTYGFPVDLT L++EEKGL +D  GFE+ ++ + L SQ  G+  +
Sbjct: 834  SSTSVLPGDVAWRLYDTYGFPVDLTLLMSEEKGLSIDNEGFEKAKQHSLLMSQAGGSTVD 655

Query: 461  DLIMLDIYAIEELRAKGLEATDDSPKYNYQSDSSGSYVFECTVATVLALRREKMFVDEVV 520
            D I L++++I EL+ +G+  TDDSPKYNY +D  G+Y FE     V+ALR  K FVDEV 
Sbjct: 654  DQISLEVHSINELQNRGIAPTDDSPKYNYTADVEGNYQFESCAGKVIALRYNKAFVDEVT 475

Query: 521  TGQECGVVLDKTCFYAEQGGQIYDEGYLVKVDDSSEDKTEFTVKNAQVRGGYVLHIGTIY 580
            +GQECGV+LDKTCFYAEQGGQIYDEG+LVK     E++ EF VKN QVRGGYVLHIG I 
Sbjct: 474  SGQECGVLLDKTCFYAEQGGQIYDEGFLVK---EGEEEVEFKVKNVQVRGGYVLHIGVIE 304

Query: 581  GNLKVGDQVRLFIDEPRRRPVMSNHTATHILNFALRSVLGEADQKGSLVAPDRLRFDFTA 640
            G LKVGD ++L IDE RR  VM NHT TH+LNF LRSVL EADQ+GSLVAPDRLRFDFTA
Sbjct: 303  GTLKVGDTMKLTIDESRRCAVMKNHTGTHMLNFGLRSVLKEADQRGSLVAPDRLRFDFTA 124

Query: 641  KGAMSTQQIKKAEEIVNGMIEAAKPVYTQDCPLAAAKAIQG 681
            KGAM  Q++K  EE+VN M    + VY Q+  LA AK+IQG
Sbjct: 123  KGAMKIQEVKNVEEVVNNMASKNEEVYGQEMGLALAKSIQG 1
>33800
          Length = 284

 Score = 53.9 bits (128), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 22/55 (40%), Positives = 43/55 (78%)
 Frame = -1

Query: 826 MDDLDRASKADVQKRVLEKTKQLIDSNPNQPLVILEMESGASAKALNEALKLFKT 880
           +DD+D+A KA +   V+E++K++I+++PNQ  V+ +  +G++AKAL+ A+K +K+
Sbjct: 170 VDDMDKARKAAIMNEVVEESKRMIEASPNQKFVVHQFSAGSNAKALDGAIKQYKS 6
>17051
          Length = 406

 Score = 30.4 bits (67), Expect = 3.2,   Method: Composition-based stats.
 Identities = 15/42 (35%), Positives = 20/42 (47%)
 Frame = -2

Query: 880 THSPQTSAMLFTVDNEAGKITCLCQVPQNAANRGLKASEWVQ 921
           TH  QT A++ T  +    + CLC V  N   R L+   W Q
Sbjct: 270 THYTQTCAVIHTRAHPLVNLMCLCNVLNN*NARKLQNERWCQ 145
>13135
          Length = 849

 Score = 29.6 bits (65), Expect = 5.8,   Method: Compositional matrix adjust.
 Identities = 28/123 (22%), Positives = 52/123 (42%), Gaps = 7/123 (5%)
 Frame = -1

Query: 358 GDAFPELKKDPEMVKDIIN---EEEVQFLKTLSRGRRILDRKIQSLGDCKTIPGDTAWLL 414
           G+   E+ KD ++   + N   ++EVQ++ T+ R            G  +TIP   A   
Sbjct: 693 GNIISEINKDVQLXCVVENKPIDKEVQWVGTVVRN-----------GTTRTIPVSIATRS 547

Query: 415 YDTYGFPVDLTGLIAE----EKGLVVDMNGFEEERRLAQLKSQGKGAGDEDLIMLDIYAI 470
           YD + + +DL    +     + G V D   +  +    QL +Q        L+++ +  I
Sbjct: 546 YDPFKYSIDLPSPTSWRLRIQNGQVTDEGVYTCQ---VQLSNQNYAKAFHQLVIIQMPQI 376

Query: 471 EEL 473
            +L
Sbjct: 375 SDL 367
>32306
          Length = 441

 Score = 29.3 bits (64), Expect = 8.3,   Method: Compositional matrix adjust.
 Identities = 23/80 (28%), Positives = 38/80 (47%), Gaps = 2/80 (2%)
 Frame = +1

Query: 34  LDDPTLLFANAGMNQFKPI--FLNTIDPSHPMAKLSRAANTQKCIRAGGKHNDLDDVGKD 91
           +DD T  +AN  +N  KPI  F  T+ P   + +++ A   Q  + A  +  D +D  ++
Sbjct: 28  IDDLTQRYANIEVNVSKPIVPFRETVIPRPKVDRVNEAIQDQNTVLASARLKDFED-DRE 204

Query: 92  VYHHTFFEMLGSWSFGDYFK 111
           V       ML   + G +FK
Sbjct: 205 VXDEGLVSMLTPNTSG-WFK 261
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31560653|ref|NP_032852.2| phosphofructokinase, liver,
B-type [Mus musculus]
         (780 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

03664                                                                 514   e-146
05449                                                                 353   1e-97
>03664
          Length = 1237

 Score =  514 bits (1324), Expect = e-146,   Method: Compositional matrix adjust.
 Identities = 249/384 (64%), Positives = 298/384 (77%), Gaps = 1/384 (0%)
 Frame = +3

Query: 7   EKLRMSG-AGKAIGVLTSGGDAQGMNAAVRAVTRMGIYVGAKVFLIXXXXXXXXXXXXNI 65
           +K++  G  G  IGV TSGGD+QGMN AVRAV RMG Y+G KV++I            NI
Sbjct: 75  QKIQAGGWVGNTIGVFTSGGDSQGMNGAVRAVVRMGFYLGCKVYVIREGYQGMVDGGENI 254

Query: 66  KPANWLSVSNIIQLGGTIIGSARCKAFTTREGRLAAAYNLLQHGITNLCVIGGDGSLTGA 125
           + A W SVS I+QLGGT+IGSAR   F  REGRL AA NL++ GITNL VIGGDGSLTGA
Sbjct: 255 EEATWASVSGILQLGGTVIGSARSADFRQREGRLKAAANLVKRGITNLVVIGGDGSLTGA 434

Query: 126 NIFRNEWGSLLEELVKEGKISESTAQNYAHLTIAGLVGSIDNDFCGTDMTIGTDSALHRI 185
           ++FR EW SLL EL ++G+++        HL I G+VGSIDNDFCGTDMTIGTDSALHRI
Sbjct: 435 DLFRREWASLLTELKEKGELTGDEMVRCQHLNIVGMVGSIDNDFCGTDMTIGTDSALHRI 614

Query: 186 MEVIDAITTTAQSHQRTFVLEVMGRHCGYLALVSALASGADWLFIPEAPPEDGWENFMCE 245
           +E +DAI+TTA SHQR FV+EVMGRHCGYLALV+ALA  ADW+FIPE PPE  W+  +C 
Sbjct: 615 IEAVDAISTTAISHQRAFVMEVMGRHCGYLALVAALACEADWVFIPEWPPEGDWKTTLCN 794

Query: 246 RLGETRSRGSRLNIIIIAEGAIDRHGKPISSSYVKDLVVQRLGFDTRVTVLGHVQRGGTP 305
           +L   R  G RLNII++AEGAIDR G  I+S  VKDL+   L +DTRVTVLGHVQRGG+P
Sbjct: 795 KLLSERKLGQRLNIILVAEGAIDREGNSITSDQVKDLLTNELKYDTRVTVLGHVQRGGSP 974

Query: 306 SAFDRILSSKMGMEAVMALLEATPDTPACVVSLSGNQSVRLPLMECVQVTKDVQKAMDEE 365
           SAFDRIL S+MG EAV+AL++ATPDTPACVVSL GNQ+VR+PLMECV  TKDVQKAMD +
Sbjct: 975 SAFDRILGSRMGAEAVLALMDATPDTPACVVSLEGNQTVRVPLMECVSRTKDVQKAMDMK 1154

Query: 366 RFDEAIQLRGRSFENNWKIYKLLA 389
            F+EA+QLRG+SF+NN   Y++L+
Sbjct: 1155NFEEAVQLRGKSFQNNLTTYRMLS 1226

 Score =  135 bits (339), Expect = 9e-32,   Method: Compositional matrix adjust.
 Identities = 105/365 (28%), Positives = 184/365 (50%), Gaps = 30/365 (8%)
 Frame = +3

Query: 401 SLAILNVGAPAAGMNAAVRSAVRTGISEGHTVYIVHDGFEGLAKG--QVQEVGWHDVAGW 458
           ++ +   G  + GMN AVR+ VR G   G  VY++ +G++G+  G   ++E  W  V+G 
Sbjct: 108 TIGVFTSGGDSQGMNGAVRAVVRMGFYLGCKVYVIREGYQGMVDGGENIEEATWASVSGI 287

Query: 459 LGRGGSMLGTKRTLPKPHLEAIVE---NLRTYNIHALLVIGGFEAYEG----------VL 505
           L  GG+++G+ R+      E  ++   NL    I  L+VIGG  +  G          +L
Sbjct: 288 LQLGGTVIGSARSADFRQREGRLKAAANLVKRGITNLVVIGGDGSLTGADLFRREWASLL 467

Query: 506 QLVEARG--------RYEELCIVMCVIPATISNNVPGTDFSLGSDTAVNAAMESCDRIKQ 557
             ++ +G        R + L IV  V   +I N+  GTD ++G+D+A++  +E+ D I  
Sbjct: 468 TELKEKGELTGDEMVRCQHLNIVGMV--GSIDNDFCGTDMTIGTDSALHRIIEAVDAIST 641

Query: 558 SASGTKRRVFIVETMGGYCGYLATVTGIAVGADAAYVFEDPFNIHDLKANV-EHMTEKMK 616
           +A  + +R F++E MG +CGYLA V  +A  AD  ++ E P    D K  +   +  + K
Sbjct: 642 TAI-SHQRAFVMEVMGRHCGYLALVAALACEADWVFIPEWPPE-GDWKTTLCNKLLSERK 815

Query: 617 TDIQRGLVLRNEKCHEH----YTTEFLYNLYSSEGRGVFDCRTNVLGHLQQGGAPTPFDR 672
              +  ++L  E   +      T++ + +L ++E +  +D R  VLGH+Q+GG+P+ FDR
Sbjct: 816 LGQRLNIILVAEGAIDREGNSITSDQVKDLLTNELK--YDTRVTVLGHVQRGGSPSAFDR 989

Query: 673 NYGTKLGVKAMLWVSEKLRDVYRKGRVFANAPDS-ACVIGLRKKVVAFSPVTE-LKKETD 730
             G+++G +A+L + +               PD+ ACV+ L        P+ E + +  D
Sbjct: 990 ILGSRMGAEAVLALMDA-------------TPDTPACVVSLEGNQTVRVPLMECVSRTKD 1130

Query: 731 FEHRM 735
            +  M
Sbjct: 1131VQKAM 1145
>05449
          Length = 724

 Score =  353 bits (907), Expect = 1e-97,   Method: Compositional matrix adjust.
 Identities = 165/237 (69%), Positives = 196/237 (82%), Gaps = 5/237 (2%)
 Frame = +3

Query: 158 IAGLVGSIDNDFCGTDMTIGTDSALHRIMEVIDAITTTAQSHQRTFVLEVMGRHCGYLAL 217
           I G+VGSIDNDFCGTDMTIGTDSALHRI+E +DAI+TTA SHQR FV+EVMGRHCGYLAL
Sbjct: 3   IVGMVGSIDNDFCGTDMTIGTDSALHRIIEAVDAISTTAISHQRAFVMEVMGRHCGYLAL 182

Query: 218 VSALASGADWLFIPEAPPEDGWENFMCERLGET-----RSRGSRLNIIIIAEGAIDRHGK 272
           V+ALA  ADW+FIPE PPE  W+  +C +L  +     R  G RLNII++AEGAIDR G 
Sbjct: 183 VAALACEADWVFIPEWPPEGDWKTTLCNKLLSSVALQERKLGQRLNIILVAEGAIDREGN 362

Query: 273 PISSSYVKDLVVQRLGFDTRVTVLGHVQRGGTPSAFDRILSSKMGMEAVMALLEATPDTP 332
            I+S  VKDL+   L +DTRVTVLGHVQRGG+PSAFDRIL S+MG EAV+AL++ATPDTP
Sbjct: 363 SITSDQVKDLLTNELKYDTRVTVLGHVQRGGSPSAFDRILGSRMGAEAVLALMDATPDTP 542

Query: 333 ACVVSLSGNQSVRLPLMECVQVTKDVQKAMDEERFDEAIQLRGRSFENNWKIYKLLA 389
           ACVVSL GNQ+VR+PLMECV  TKDVQKAMD + F+EA+QLRG+SF+NN   Y++L+
Sbjct: 543 ACVVSLEGNQTVRVPLMECVSRTKDVQKAMDMKNFEEAVQLRGKSFQNNLTTYRMLS 713

 Score = 90.5 bits (223), Expect = 2e-18,   Method: Compositional matrix adjust.
 Identities = 63/213 (29%), Positives = 109/213 (51%), Gaps = 10/213 (4%)
 Frame = +3

Query: 527 TISNNVPGTDFSLGSDTAVNAAMESCDRIKQSASGTKRRVFIVETMGGYCGYLATVTGIA 586
           +I N+  GTD ++G+D+A++  +E+ D I  +A  + +R F++E MG +CGYLA V  +A
Sbjct: 21  SIDNDFCGTDMTIGTDSALHRIIEAVDAISTTAI-SHQRAFVMEVMGRHCGYLALVAALA 197

Query: 587 VGADAAYVFEDPFN-------IHDLKANVEHMTEKMKTDIQRGLVLRNEKCHE--HYTTE 637
             AD  ++ E P          + L ++V     K+   +   LV       E    T++
Sbjct: 198 CEADWVFIPEWPPEGDWKTTLCNKLLSSVALQERKLGQRLNIILVAEGAIDREGNSITSD 377

Query: 638 FLYNLYSSEGRGVFDCRTNVLGHLQQGGAPTPFDRNYGTKLGVKAMLWVSEKLRDVYRKG 697
            + +L ++E +  +D R  VLGH+Q+GG+P+ FDR  G+++G +A+L + +         
Sbjct: 378 QVKDLLTNELK--YDTRVTVLGHVQRGGSPSAFDRILGSRMGAEAVLALMDA-------- 527

Query: 698 RVFANAPDS-ACVIGLRKKVVAFSPVTELKKET 729
                 PD+ ACV+ L        P+ E    T
Sbjct: 528 -----TPDTPACVVSLEGNQTVRVPLMECVSRT 611
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|61651673|ref|NP_077184.2| source of immunodominant
MHC-associated peptides [Mus musculus]
         (823 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

08971                                                                 515   e-146
25627                                                                  30   2.9  
27704                                                                  30   4.3  
30147                                                                  29   8.4  
>08971
          Length = 3836

 Score =  515 bits (1326), Expect = e-146,   Method: Compositional matrix adjust.
 Identities = 246/439 (56%), Positives = 316/439 (71%), Gaps = 8/439 (1%)
 Frame = -3

Query: 61   QPAGWQSLLSFTILFLAWLAGFSSRLFAVIRFESIIHEFDPWFNYRSTHHLASHGFYEFL 120
             P    +LL   +L +A +  FS+RLF+V+RFES+IHEFDP+FNYR+T  LA  GFY F 
Sbjct: 3702 SPDKQDTLLKMMVLAIAAVLSFSTRLFSVLRFESVIHEFDPYFNYRTTRFLAEEGFYNFH 3523

Query: 121  NWFDERAWYPLGRIVGGTVYPGLMITAGLIHWILNTLNITVHIRDVCVFLAPTFSGLTSI 180
            NWFD+RAWYPLGRI+GGT+YPGLM+T+  I+ +LN  NIT+ +R+VCVFLAP FS  T+I
Sbjct: 3522 NWFDDRAWYPLGRIIGGTIYPGLMVTSAAIYHVLNFFNITIDVRNVCVFLAPLFSSFTTI 3343

Query: 181  STFLLTRELWNQGAGLLAACFIAIVPGYISRSVAGSFDNEGIAIFALQFTYYLWVKSVKT 240
             TF LT+EL +  AGL+AA  +AIVPGYISRSVAGS+DNEGIAIF +  TYYLW+K+VKT
Sbjct: 3342 VTFFLTKELKDASAGLVAASMLAIVPGYISRSVAGSYDNEGIAIFCMLLTYYLWIKAVKT 3163

Query: 241  GSVFWTMCCCLSYFYMVSAWGGYVFIINLIPLHVFVLLLMQRYSKRVYIAYSTFYIVGLI 300
            GS++W   C L+YFYMVS+WGGYVF+INLIPLHV  L++  R+S ++Y+AYST Y +G +
Sbjct: 3162 GSIYWGALCSLAYFYMVSSWGGYVFLINLIPLHVLALMVTGRFSHKIYLAYSTVYCLGTL 2983

Query: 301  LSMQIPFVGFQPIRTSEHMAAAGVXXXXXXXXXXXXXRDRLTKQEFQTLFFLGVSLAAGA 360
            LSMQI FVGFQP+++SEHMAA GV             R RL++++F  LF   V L    
Sbjct: 2982 LSMQISFVGFQPVQSSEHMAALGVFGLCQIHAFVDYLRSRLSREQFNLLFRSLVLLTGTI 2803

Query: 361  VFLSVIYLTYTGYIAPWSGRFYSLWDTGYAKIHIPIIASVSEHQPTTWVSFFFDLHILVC 420
             F +    T  G I+PW+GRFYSL D  YAK +IPIIASVSEHQPTTW SF+FDL +LV 
Sbjct: 2802 AFGAAAVATAMGKISPWTGRFYSLLDPSYAKNNIPIIASVSEHQPTTWSSFYFDLQLLVF 2623

Query: 421  TFPAGLWFCIKNINDERVFVALYAISAVYFAGVMVRLMLTLTPVVCMLSAIAFSNVFEHY 480
             FP GL+FC   + D  +F+ +Y ++++YFAGVMVRLML L PV+C+LS I  S +   Y
Sbjct: 2622 MFPVGLYFCFSKLTDANIFIVMYGVTSIYFAGVMVRLMLVLAPVMCILSGIGVSAILTAY 2443

Query: 481  LGD--------DMKRENPP 491
            + +        + K   PP
Sbjct: 2442 MKNLDSSRKDKNXKNRTPP 2386

 Score =  268 bits (685), Expect = 7e-72,   Method: Compositional matrix adjust.
 Identities = 143/272 (52%), Positives = 177/272 (65%), Gaps = 3/272 (1%)
 Frame = -2

Query: 507  LYDKAGKVRKHVTEQEKPEEG--LGPNIKSIVTXXXXXXXXXFAVHCTWVTSNAYSSPSV 564
            L++K  +++    E +KP+    L   I + V          +  HCTWVTS AYSSPS+
Sbjct: 2446 LHEKP-RLQPQRQEPKKPDSTYPLKNEIANGVILIITAFLILYTFHCTWVTSEAYSSPSI 2270

Query: 565  VLASYNHDGTRNILDDFREAYFWLRQNTDEHARVMSWWDYGYQIAGMANRTTLVDNNTWN 624
            VL++   DG+R I DDFREAY+WLR NT E+++VMSWWDYGYQI  MANRT LVDNNTWN
Sbjct: 2269 VLSARGGDGSRIIFDDFREAYYWLRHNTPENSKVMSWWDYGYQITAMANRTILVDNNTWN 2090

Query: 625  NSHIALVGKAMSSNETAAYKIMRSLDVDYVLVIFGGVIGYSGDDINKFLWMVRI-AEGEH 683
            N+HI+ VG+AM+S E +     R+      L  F            + LWMVRI    + 
Sbjct: 2089 NTHISRVGQAMASTEESVRDNARA*R-QLRLSDFWWPHWLLLRRHQQVLWMVRIGGSTDR 1913

Query: 684  PKDIREGDYFTQQGEFRVDKAGSPTLLNCLMYKMSYYRFGEMQLDFRTPPGFDRTRNAEI 743
             K I E DY+T QGEFRVD+ GSP LLNCLMYKM YYRFG +  +   P G+DR RNAEI
Sbjct: 1912 GKHIHEMDYYTPQGEFRVDREGSPVLLNCLMYKMCYYRFGAVYTESGQPTGYDRVRNAEI 1733

Query: 744  GNKDIKFKHLEEAFTSEHWLVRIYKVKAPDNR 775
            GNKD +   LEEA+T+EHWLVRIYKVK  +NR
Sbjct: 1732 GNKDFELDVLEEAYTTEHWLVRIYKVKDLENR 1637
>25627
          Length = 390

 Score = 30.4 bits (67), Expect = 2.9,   Method: Composition-based stats.
 Identities = 13/42 (30%), Positives = 20/42 (47%)
 Frame = -2

Query: 381 FYSLWDTGYAKIHIPIIASVSEHQPTTWVSFFFDLHILVCTF 422
           +Y  +   Y  +H  I   VS++QP T    F   H  +CT+
Sbjct: 224 YYCAYTHTYLSLHAQIDIHVSQNQPRTHTHLFLSTHTCMCTY 99
>27704
          Length = 646

 Score = 30.0 bits (66), Expect = 4.3,   Method: Composition-based stats.
 Identities = 14/38 (36%), Positives = 18/38 (47%)
 Frame = +2

Query: 495 SSDEDDKRNPGNLYDKAGKVRKHVTEQEKPEEGLGPNI 532
           S DEDD  NP N  D+     KH    +K E+    N+
Sbjct: 131 SVDEDDNNNPENRTDRTTASSKHDGMSQKTEDNTTDNV 244
>30147
          Length = 526

 Score = 28.9 bits (63), Expect = 8.4,   Method: Composition-based stats.
 Identities = 11/36 (30%), Positives = 24/36 (66%)
 Frame = -2

Query: 245 WTMCCCLSYFYMVSAWGGYVFIINLIPLHVFVLLLM 280
           +++CC LS F+ + +   YVF ++L+ +++  LL +
Sbjct: 258 YSVCCFLSPFFKIKSHCIYVFYLSLVLVNILSLLFL 151
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6671684|ref|NP_031640.1| catenin (cadherin associated
protein), beta 1, 88kDa [Mus musculus]
         (781 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

14657                                                                 508   e-144
15086                                                                 295   5e-80
12505                                                                 116   5e-30
38361                                                                 107   9e-28
17600                                                                 104   1e-22
12579                                                                  96   4e-20
36452                                                                  46   7e-05
28685                                                                  35   0.10 
36960                                                                  29   6.3  
>14657
          Length = 918

 Score =  508 bits (1308), Expect = e-144,   Method: Compositional matrix adjust.
 Identities = 251/305 (82%), Positives = 272/305 (89%), Gaps = 1/305 (0%)
 Frame = -3

Query: 102 TLDEGMQIPSTQFDAAHPTNVQRLAEPSQMLKHAVVNLINYQDDAELATRAIPELTKLLN 161
           TL EG+QIPSTQ     PT VQRL+EPSQMLKHAVVNLINYQDDA+LATRAIPEL KLL 
Sbjct: 916 TLPEGVQIPSTQVHPDEPTAVQRLSEPSQMLKHAVVNLINYQDDADLATRAIPELIKLLX 737

Query: 162 DEDQVVVNKAAVMVHQLSKKEASRHAIMRSPQMVSAIVRTMQNTNDVETARCTAGTLHNL 221
           DED VVV +AA+MVHQLSKKEASRHAIM SPQM++A++R M NT D+ET RC AGTLHNL
Sbjct: 736 DEDXVVVYQAAMMVHQLSKKEASRHAIMNSPQMIAALIRAMANTEDIETTRCAAGTLHNL 557

Query: 222 SHHREGLLAIFKSGGIPALVKMLGSPVDSVLFYAITTLHNLLLHQEGAKMAVRLAGGLQK 281
           SHHR+GLLAIFKSGGIPALVK+L SP++SVLFYAITTLHNLLLHQEG+KMAVRLAGGLQK
Sbjct: 556 SHHRQGLLAIFKSGGIPALVKLLSSPMESVLFYAITTLHNLLLHQEGSKMAVRLAGGLQK 377

Query: 282 MVALLNK-TNVKFLAITTDCLQILAYGNQESKLIILASGGPQALVNIMRTYTYEKLLWTT 340
           MVALL +  NVKFLAITTDCLQILAYGNQESKLIILASGGP  LV IM++YTYEKLLWTT
Sbjct: 376 MVALLQRNNNVKFLAITTDCLQILAYGNQESKLIILASGGPGELVRIMKSYTYEKLLWTT 197

Query: 341 SRVLKVLSVCSSNKPAIVEAGGMQALGLHLTDPSQRLVQNCLWTLRNLSDAATKQEGMEG 400
           SRVLKVLSVC SNKPAIVEAGGMQAL +HL   SQRLVQNCLW+LRNLSDAATK + MEG
Sbjct: 196 SRVLKVLSVCPSNKPAIVEAGGMQALAMHLGHQSQRLVQNCLWSLRNLSDAATKMDNMEG 17

Query: 401 LLGTL 405
           LL  L
Sbjct: 16  LLHML 2

 Score = 33.9 bits (76), Expect = 0.25,   Method: Compositional matrix adjust.
 Identities = 49/177 (27%), Positives = 78/177 (44%), Gaps = 4/177 (2%)
 Frame = -3

Query: 370 LTDPSQRLVQNC--LWTLRNLSDAATKQEGMEGLLGTLVQLLGSDDINVVTCAAGILSNL 427
           L++PSQ L      L   ++ +D AT+       +  L++LL  +D  VV  AA ++  L
Sbjct: 847 LSEPSQMLKHAVVNLINYQDDADLATRA------IPELIKLLXDEDXVVVYQAAMMVHQL 686

Query: 428 TCNNYKNKMMVCQVGGIEALVRTVLRAGDREDITEPAICA--LRHLTSRHQEAEMAQNAV 485
           +        ++     I AL+R +    + EDI E   CA    H  S H++  +A   +
Sbjct: 685 SKKEASRHAIMNSPQMIAALIRAM---ANTEDI-ETTRCAAGTLHNLSHHRQGLLA---I 527

Query: 486 RLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLLVR 542
               G+P +VKLL  P    L  A   L   L     +   +R  G + ++V LL R
Sbjct: 526 FKSGGIPALVKLLSSPMESVLFYAITTLHNLLLHQEGSKMAVRLAGGLQKMVALLQR 356
>15086
          Length = 548

 Score =  295 bits (755), Expect = 5e-80,   Method: Compositional matrix adjust.
 Identities = 143/171 (83%), Positives = 159/171 (92%), Gaps = 1/171 (0%)
 Frame = +1

Query: 152 AIPELTKLLNDEDQVVVNKAAVMVHQLSKKEASRHAIMRSPQMVSAIVRTMQNTNDVETA 211
           AIPEL KLL+DEDQVVV +AA+MVHQLSKKEASRHAIM SPQM++A++R +  T+D+ET 
Sbjct: 1   AIPELIKLLSDEDQVVVCQAAMMVHQLSKKEASRHAIMNSPQMIAALIRALATTDDMETT 180

Query: 212 RCTAGTLHNLSHHREGLLAIFKSGGIPALVKMLGSPVDSVLFYAITTLHNLLLHQEGAKM 271
           RC AGTLHNLSHHR+GLLAIFKSGGIPALVK+L SPV+SVLFYAITTLHNLLLHQEG+KM
Sbjct: 181 RCAAGTLHNLSHHRQGLLAIFKSGGIPALVKLLSSPVESVLFYAITTLHNLLLHQEGSKM 360

Query: 272 AVRLAGGLQKMVALLNK-TNVKFLAITTDCLQILAYGNQESKLIILASGGP 321
           AVR+AGGLQKMVALL +  NVKFLAITTDCLQILAYGNQESKLIILASGGP
Sbjct: 361 AVRMAGGLQKMVALLQRNNNVKFLAITTDCLQILAYGNQESKLIILASGGP 513

 Score = 31.6 bits (70), Expect = 1.4,   Method: Compositional matrix adjust.
 Identities = 39/138 (28%), Positives = 61/138 (44%)
 Frame = +1

Query: 405 LVQLLGSDDINVVTCAAGILSNLTCNNYKNKMMVCQVGGIEALVRTVLRAGDREDITEPA 464
           L++LL  +D  VV  AA ++  L+        ++     I AL+R +    D E  T  A
Sbjct: 13  LIKLLSDEDQVVVCQAAMMVHQLSKKEASRHAIMNSPQMIAALIRALATTDDMET-TRCA 189

Query: 465 ICALRHLTSRHQEAEMAQNAVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLALCPANH 524
              L +L S H++  +A   +    G+P +VKLL  P    L  A   L   L     + 
Sbjct: 190 AGTLHNL-SHHRQGLLA---IFKSGGIPALVKLLSSPVESVLFYAITTLHNLLLHQEGSK 357

Query: 525 APLREQGAIPRLVQLLVR 542
             +R  G + ++V LL R
Sbjct: 358 MAVRMAGGLQKMVALLQR 411
>12505
          Length = 836

 Score =  116 bits (290), Expect(2) = 5e-30,   Method: Compositional matrix adjust.
 Identities = 57/80 (71%), Positives = 60/80 (75%)
 Frame = -3

Query: 592 GLNTIPLFVQLLYSPIENIQRVAAGVLCELAQDKXXXXXXXXXXXXXPLTELLHSRNEGV 651
           G+  +  + QLLYSPIENIQRVAAGVLCELA DK             PLTELLHSRNEGV
Sbjct: 732 GVGAVLRYHQLLYSPIENIQRVAAGVLCELAADKEGAEMIEQEGATAPLTELLHSRNEGV 553

Query: 652 ATYAAAVLFRMSEDKPQDYK 671
            TYAAAVLFRMSEDKPQDYK
Sbjct: 552 XTYAAAVLFRMSEDKPQDYK 493

 Score = 33.9 bits (76), Expect(2) = 5e-30,   Method: Compositional matrix adjust.
 Identities = 17/31 (54%), Positives = 23/31 (74%), Gaps = 3/31 (9%)
 Frame = -2

Query: 671 KKRLSVELTSSLFRTEPMAWNETA---DLGL 698
           +KRLS+ELTSSL+R + M W+E     D+GL
Sbjct: 496 QKRLSMELTSSLYRGDNMNWSEPPGFEDVGL 404

 Score = 80.9 bits (198), Expect = 2e-15,   Method: Composition-based stats.
 Identities = 37/44 (84%), Positives = 43/44 (97%)
 Frame = -1

Query: 215 AGTLHNLSHHREGLLAIFKSGGIPALVKMLGSPVDSVLFYAITT 258
           AGTLHNLSHHR+GLLAIF+SGGIPALVK+L SP++SVLFYAIT+
Sbjct: 833 AGTLHNLSHHRQGLLAIFRSGGIPALVKLLSSPMESVLFYAITS 702
>38361
          Length = 227

 Score =  107 bits (268), Expect(2) = 9e-28,   Method: Compositional matrix adjust.
 Identities = 50/63 (79%), Positives = 55/63 (87%)
 Frame = -1

Query: 457 REDITEPAICALRHLTSRHQEAEMAQNAVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRN 516
           R  +   ++CALRHLTSRH EAEMAQNAVRLHYGLPV+VKLLHPPS WPLIKA VGL+RN
Sbjct: 191 RTSLNLDSVCALRHLTSRHPEAEMAQNAVRLHYGLPVLVKLLHPPSRWPLIKAVVGLVRN 12

Query: 517 LAL 519
           LAL
Sbjct: 11  LAL 3

 Score = 34.7 bits (78), Expect(2) = 9e-28,   Method: Compositional matrix adjust.
 Identities = 14/17 (82%), Positives = 16/17 (94%)
 Frame = -3

Query: 447 LVRTVLRAGDREDITEP 463
            VRTV++AGDREDITEP
Sbjct: 225 FVRTVMQAGDREDITEP 175
>17600
          Length = 752

 Score =  104 bits (260), Expect = 1e-22,   Method: Compositional matrix adjust.
 Identities = 66/135 (48%), Positives = 82/135 (60%), Gaps = 15/135 (11%)
 Frame = +1

Query: 639 PLTELLHSRNEGVATYAAAVLFRMSEDKPQDYKKRLSVELTSSLFRTEPMAWNETA---D 695
           PLT+LLHSRNEGVATYAAAVLFRMSEDKPQDYKKRLS+ELTSSL+R + M W+E     D
Sbjct: 292 PLTDLLHSRNEGVATYAAAVLFRMSEDKPQDYKKRLSMELTSSLYRGDNMNWSEPPGFED 471

Query: 696 LGLDIGAQGEALGYRQDDPSYRSFHSGGY--------GQDALGMDPMMEHEMGGHHPGA- 746
           +GL      + +  +Q  P ++   S  Y        G+   G D +  + M G   GA 
Sbjct: 472 MGLLTDTSRDPMYSQQQLPPHQGSQSSMYSGSQHDMQGRPPTGYDQVPVNSMQGLDLGAA 651

Query: 747 ---DYPVDGLPDLGH 758
                P+D +PDLG 
Sbjct: 652 GAYGGPLDNIPDLGQ 696
>12579
          Length = 1870

 Score = 96.3 bits (238), Expect = 4e-20,   Method: Compositional matrix adjust.
 Identities = 61/123 (49%), Positives = 78/123 (63%), Gaps = 6/123 (4%)
 Frame = +2

Query: 10  LDMAMEPDRKAAVSHWQQQSYL-DSGIHSGATTTAPSLSGKGNPEE---EDVDTSQVLYE 65
           LDM ++  +      WQQ  YL DSGIHSGATT APS+S KG+ EE    D+D ++ +++
Sbjct: 92  LDMPVD-SKHEQTMMWQQNQYLADSGIHSGATTQAPSISSKGHGEELEEGDMDPTK-MFD 265

Query: 66  WEQGFSQSFTQ--EQVADIDGQYAMTRAQRVRAAMFPETLDEGMQIPSTQFDAAHPTNVQ 123
           W  G    FT   EQV +++ Q   TR QRVRAA+FPE+L EG+QIPSTQ     PT V 
Sbjct: 266 W--GLPDPFTPQPEQVEEMNQQLNQTRPQRVRAAIFPESLPEGVQIPSTQVHPDQPTAVX 439

Query: 124 RLA 126
            LA
Sbjct: 440 *LA 448
>36452
          Length = 607

 Score = 45.8 bits (107), Expect = 7e-05,   Method: Compositional matrix adjust.
 Identities = 44/190 (23%), Positives = 85/190 (44%), Gaps = 5/190 (2%)
 Frame = +1

Query: 207 DVETARCTAGTLHNLSHHREGLLAIFKSGGIPALVKMLGSPVDSVLFYAITTLHNLLLHQ 266
           DVE ARC A  L + S  ++   A+ ++G IP L K+L SP + +L   + TL      +
Sbjct: 7   DVEVARCGALALWSCSKSKKNKEAMQRAGAIPLLAKLLKSPHEDMLIPVVGTLQE-CASE 183

Query: 267 EGAKMAVRLAGGLQKMVALLNKTNVKFLA---ITTDCLQIL--AYGNQESKLIILASGGP 321
              ++A+R  G ++ +V  L  +     A   +   C   +      +E++ ++   GG 
Sbjct: 184 PSYRLAIRTEGMIEDLVKNLKSSVPDKPANPELQMHCASAIFKCAEEKETRDLVRQYGGL 363

Query: 322 QALVNIMRTYTYEKLLWTTSRVLKVLSVCSSNKPAIVEAGGMQALGLHLTDPSQRLVQNC 381
             LV ++     ++LL   +  +   ++   N     E   ++ L   LT+  + ++ N 
Sbjct: 364 DPLVGLLNKMDNKELLAAATGAIWKCAISPENVARFQELKCIELLVALLTNQPEEVLVNV 543

Query: 382 LWTLRNLSDA 391
           +  L  L+ A
Sbjct: 544 VGALGELAKA 573

 Score = 32.0 bits (71), Expect = 0.87,   Method: Compositional matrix adjust.
 Identities = 56/215 (26%), Positives = 88/215 (40%), Gaps = 5/215 (2%)
 Frame = +1

Query: 382 LWTLRNLSDAATKQEGME--GLLGTLVQLLGSDDINVVTCAAGILSNLTCNNYKNKMMVC 439
           LW+    S +   +E M+  G +  L +LL S   +++    G L     +    ++ + 
Sbjct: 40  LWSC---SKSKKNKEAMQRAGAIPLLAKLLKSPHEDMLIPVVGTLQECA-SEPSYRLAIR 207

Query: 440 QVGGIEALVRTVLRAGDREDITEPAI---CALRHLTSRHQEAEMAQNAVRLHYGLPVVVK 496
             G IE LV+  L++   +    P +   CA      +  E +  ++ VR + GL  +V 
Sbjct: 208 TEGMIEDLVKN-LKSSVPDKPANPELQMHCA--SAIFKCAEEKETRDLVRQYGGLDPLVG 378

Query: 497 LLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLLVRAHQDTQRRTSMGGT 556
           LL+   +  L+ A  G I   A+ P N A  +E   I  LV LL               T
Sbjct: 379 LLNKMDNKELLAAATGAIWKCAISPENVARFQELKCIELLVALL---------------T 513

Query: 557 QQQFVEGVRMEEIVEGCTGALHILARDVHNRIVIR 591
            Q        EE++    GAL  LA+   NR  IR
Sbjct: 514 NQP-------EEVLVNVVGALGELAKAQPNRAQIR 597
>28685
          Length = 834

 Score = 35.0 bits (79), Expect = 0.10,   Method: Composition-based stats.
 Identities = 19/36 (52%), Positives = 20/36 (55%), Gaps = 7/36 (19%)
 Frame = +2

Query: 753 LPDLGHAQDL----MD---GLPPGDSNQLAWFDTDL 781
           LPDLG   DL    +D   G PPGD     WFDTDL
Sbjct: 23  LPDLGPGSDLNFDSIDPNLGAPPGDGGPSIWFDTDL 130
>36960
          Length = 551

 Score = 29.3 bits (64), Expect = 6.3,   Method: Composition-based stats.
 Identities = 16/43 (37%), Positives = 23/43 (53%)
 Frame = +3

Query: 231 IFKSGGIPALVKMLGSPVDSVLFYAITTLHNLLLHQEGAKMAV 273
           I  +GGIP ++  L S  +  +  AITTL  L+  Q  A + V
Sbjct: 321 IVTNGGIPLVINCLSSCSEETVMSAITTLMYLITPQSQAAITV 449
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|30520131|ref|NP_848818.1| solute carrier family 6
(neurotransmitter transporter, GABA), member 1 [Mus musculus]
         (599 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

08387                                                                 370   e-143
15924                                                                 318   5e-87
08953                                                                 304   5e-83
21405                                                                 152   2e-55
32211                                                                 206   3e-53
18526                                                                 194   9e-50
14556                                                                 153   2e-37
26872                                                                 135   5e-32
02570                                                                 135   6e-32
19604                                                                 130   2e-30
26038                                                                 114   1e-25
33291                                                                  75   9e-20
25926                                                                  83   4e-16
21870                                                                  78   9e-15
14638                                                                  74   2e-13
31151                                                                  50   3e-06
00472                                                                  31   1.5  
11578                                                                  28   8.8  
10280                                                                  28   9.9  
>08387
          Length = 4991

 Score =  370 bits (950), Expect(3) = e-143,   Method: Compositional matrix adjust.
 Identities = 187/418 (44%), Positives = 274/418 (65%), Gaps = 18/418 (4%)
 Frame = -2

Query: 199  QMTDGLDKPGQIRWPLAITLAIAWVLVYFCIWKGVGWTGKVVYFSATYPYIMLIILFFRG 258
            +++DG+D  G ++W LA+ L +AWV+VY CI KG+  +GKV+Y +AT PYI ++IL  R 
Sbjct: 4411 KISDGIDDMGTVKWDLALCLLLAWVVVYACICKGIRSSGKVMYVTATSPYIFMLILLIRN 4232

Query: 259  VTLPGAKEGILFYITPNFRKLSDSEVWLDAATQIFFXXXXXXXXXXXXXXYNSFHNNVYR 318
              L GAKEG+ FY+TPN  KL + EVW+DA TQIFF              YN F +N YR
Sbjct: 4231 SLLDGAKEGVDFYLTPNMTKLGEMEVWVDAGTQIFFSSSIALGTLTALGSYNKFKHNSYR 4052

Query: 319  DSIIVCCINSCTSMFAGFVIFSIVGFMAHVTKRSIADVAASGPGLAFLAYPEAVTQLPIS 378
            DS+I   +NS TS FAGF++F+I+G+MA +  R I DVA SGPGLAF+AYP+AV Q+P+S
Sbjct: 4051 DSVIFALVNSVTSFFAGFIVFTILGYMAKLQNRPIKDVAESGPGLAFIAYPKAVAQMPLS 3872

Query: 379  PLWAILFFSMLLMLGIDSQFCTVEGFITALVDEYPRLLRN--RRELFIAAVCIVSYLIGL 436
            PLW+ILFF M+++LG+DSQF  VEG +T +VD+YPRLLR   R+E+FI  +CI+ + +GL
Sbjct: 3871 PLWSILFFLMVILLGLDSQFVGVEGVVTTIVDQYPRLLRKGYRKEIFIGFICIIMFFVGL 3692

Query: 437  SNITQGGIYVFKLFDYYSASGMSLLFLVFFECVSISWFYGVNRFYDNIQEMVGS----RP 492
            + ++ GG+YVF+LFDYYS S + +L + FFE + IS+ YGV RF DNI+ M+G     + 
Sbjct: 3691 AMVSNGGMYVFQLFDYYSGSRI-ILLVAFFELIGISYIYGVFRFLDNIKMMLGDHWMVKT 3515

Query: 493  CIWWKLCWSFFTPIIVAGVFLFSAVQMT------PLTMGSYVFPKWGQGVGWLMALSSMV 546
              +  +CW+  +P     +F+ SA+  +      P + G+YV+P W  G+GW +A SS V
Sbjct: 3514 LPFMVVCWTVLSPAFCIAIFVMSAINYSELDYARPGSKGTYVYPDWAVGIGWALAASSAV 3335

Query: 547  LIPGYMAYMFLTLKGSLKQRLQVMIQP---SEDIVRPENGPEQPQAG---SSASKEAY 598
             IP    Y ++   G+  + L+++ +P    E  +R ++  E+  A      A +++Y
Sbjct: 3334 WIPIVAIYKWVK-NGATLEALKLLCKPYGLKEHQLREQDKGERTLADLERERAGEQSY 3164

 Score =  114 bits (286), Expect(3) = e-143,   Method: Compositional matrix adjust.
 Identities = 55/116 (47%), Positives = 82/116 (70%), Gaps = 5/116 (4%)
 Frame = -1

Query: 81   AFLIPYFLTLIFAGVPLFLLECSLGQYTSIGGLGVWKLAPMFKGVGLAAAVLSFWLNIYY 140
            AFLIPYF+ +IF G+PLF LE ++GQ+ + GGL  W L P+ +G+GLA+ ++ F+LN YY
Sbjct: 4790 AFLIPYFICVIFGGIPLFYLEVAVGQFMNRGGLQAWNLVPILQGIGLASCIIVFFLNCYY 4611

Query: 141  IVIISWAIYYLYNSFTTTLPWKQCDNPWNTDR-CFSNY-SLVNTT---NMTSAVVE 191
             VI++WA YY ++SFT+ LPW+ CD+ WN    C  ++ + VN T   N+T  +V+
Sbjct: 4610 NVILTWAFYYFFSSFTSELPWETCDHDWNNKTVCAVDFQAKVNETGDPNITKILVD 4443

 Score = 63.2 bits (152), Expect(3) = e-143,   Method: Compositional matrix adjust.
 Identities = 26/46 (56%), Positives = 35/46 (76%)
 Frame = -3

Query: 35   QKKAGDLPDRDTWKGRFDFLMSCVGYAIGLGNVWRFPYLCGKNGGG 80
             ++  DL  R+ W   FDFL++C+G+++GLGNVWRFPYLC KNG G
Sbjct: 4926 DEEGKDLNKREQWGRAFDFLLACIGFSVGLGNVWRFPYLCYKNGEG 4789
>15924
          Length = 2588

 Score =  318 bits (814), Expect = 5e-87,   Method: Compositional matrix adjust.
 Identities = 170/428 (39%), Positives = 257/428 (60%), Gaps = 16/428 (3%)
 Frame = +3

Query: 177 YSLVNTTNMTSAV------------VEFWERNMHQMTDGLDKP--GQIRWPLAITLAIAW 222
           YS +N+T +TS V             ++  + + ++ +  D    G I   + +TLA+AW
Sbjct: 3   YSQLNSTIVTSMVFNPCKTTWVSPAADYLSQYVLRLNEATDMANLGGISLKMILTLALAW 182

Query: 223 VLVYFCIWKGVGWTGKVVYFSATYPYIMLIILFFRGVTLPGAKEGILFYITPNFRKLSDS 282
           +L++FC+ KGV  +GKVVYF+AT+PY++L++L  RGVTL G  +G+ FY+ P + KL+D+
Sbjct: 183 LLIFFCLMKGVKSSGKVVYFTATFPYVILVVLLVRGVTLEGHLDGVKFYVIPEWDKLADA 362

Query: 283 EVWLDAATQIFFXXXXXXXXXXXXXXYNSFHNNVYRDSIIVCCINSCTSMFAGFVIFSIV 342
           +VW DAATQIF+              YN F NN YRD+I+V  IN  TS+FAGF IFS++
Sbjct: 363 KVWGDAATQIFYSLGVGFGGLLTMASYNKFKNNCYRDAIMVAVINCSTSIFAGFAIFSLL 542

Query: 343 GFMAHVTKRSIADVAASGPGLAFLAYPEAVTQLPISPLWAILFFSMLLMLGIDSQFCTVE 402
           G MAHV  +++ DVA+SGPGLAF+AYPE +T+LP   LW+ LFF M+L LG+DSQF  +E
Sbjct: 543 GHMAHVNNQAVEDVASSGPGLAFVAYPEGITKLPAQSLWSFLFFFMILTLGLDSQFAMME 722

Query: 403 GFITALVDEYPRLLRNRRELFIAAVCIVSYLIGLSNITQGGIYVFKLFDYYSASGMSLLF 462
             I+ + D +PR LR R+ LF    C+V +L+G+   T+GG++V  L D+YS S  +L+F
Sbjct: 723 TVISGISDMFPRTLRKRKVLFTFCACLVGFLLGIPQATKGGMWVLTLMDWYSGS-YNLMF 899

Query: 463 LVFFECVSISWFYGVNRFYDNIQEMVGSRPCIWWKLCWSFFTPIIVAGVFLFSAVQMTPL 522
           +   E + I + YG   F ++++ MVG +P I+W   W   TPI +  + +  A+Q TP 
Sbjct: 900 VALAELICIMYVYGWRNFSNDVEMMVGFKPNIYWLANWLVITPIAIGFIIIIGAIQYTPA 1079

Query: 523 TMGSYVFPKWGQGVGWLMALSSM--VLIPGYMAYMFLTLKGSLKQRLQVMIQPSEDIVRP 580
           +   Y F  W QG+GW+M    +  + + G++      + G  K              +P
Sbjct: 1080SYDGYEFEDWVQGLGWVMVTVPIASIFVVGFVQMARYGVPGCFK-------------AQP 1220

Query: 581 ENGPEQPQ 588
           + GP  P+
Sbjct: 1221DWGPANPE 1244
>08953
          Length = 2245

 Score =  304 bits (779), Expect = 5e-83,   Method: Compositional matrix adjust.
 Identities = 154/333 (46%), Positives = 223/333 (66%)
 Frame = +1

Query: 216 ITLAIAWVLVYFCIWKGVGWTGKVVYFSATYPYIMLIILFFRGVTLPGAKEGILFYITPN 275
           +TLA+AW+L++FC+ KGV  +GKVVYF+AT+PY++L++L  RGVTL G  EGI FY  P 
Sbjct: 10  LTLALAWILIFFCLMKGVKSSGKVVYFTATFPYVILLVLLVRGVTLSGHLEGIKFYTIPK 189

Query: 276 FRKLSDSEVWLDAATQIFFXXXXXXXXXXXXXXYNSFHNNVYRDSIIVCCINSCTSMFAG 335
           + KL+D++VW DAATQIF+              Y+ F NN +RD+I+V  IN  TS+FAG
Sbjct: 190 WDKLADAKVWGDAATQIFYSLGVGFGGLLTMSSYSKFKNNCHRDAIMVALINCGTSIFAG 369

Query: 336 FVIFSIVGFMAHVTKRSIADVAASGPGLAFLAYPEAVTQLPISPLWAILFFSMLLMLGID 395
           F IF+++G MA+VT + +  VA SGPGLAF+AYPE +T+LP   LWA LFF M+L LG+D
Sbjct: 370 FAIFALLGHMAYVTNQDVDKVADSGPGLAFVAYPEGITKLPAMSLWAFLFFFMILTLGLD 549

Query: 396 SQFCTVEGFITALVDEYPRLLRNRRELFIAAVCIVSYLIGLSNITQGGIYVFKLFDYYSA 455
           SQF  +E  I+ + D +PRLLR  +  F    C+V +L+G+   T+GG++V  L D+YS 
Sbjct: 550 SQFAMMETVISGISDMFPRLLRKHKTFFTFICCLVGFLLGIPQATKGGMWVLTLMDWYSG 729

Query: 456 SGMSLLFLVFFECVSISWFYGVNRFYDNIQEMVGSRPCIWWKLCWSFFTPIIVAGVFLFS 515
           S  +L+F+   E + + + YG N+FY++I+ M+G +P  +W++ W   TPI +  + +  
Sbjct: 730 S-YNLMFVALAEIICLMYVYGFNKFYEDIEMMIGHKPNYYWRIHWLAITPIAIIFIIVIG 906

Query: 516 AVQMTPLTMGSYVFPKWGQGVGWLMALSSMVLI 548
           AVQ TP +   Y F  W QG+GW+M    + LI
Sbjct: 907 AVQYTPASYSGYEFEBWVQGLGWVMVSVPIALI 1005
>21405
          Length = 542

 Score =  152 bits (384), Expect(2) = 2e-55,   Method: Compositional matrix adjust.
 Identities = 68/125 (54%), Positives = 89/125 (71%)
 Frame = +2

Query: 418 NRRELFIAAVCIVSYLIGLSNITQGGIYVFKLFDYYSASGMSLLFLVFFECVSISWFYGV 477
            R+E+FIA VC++SYL+GL+ ITQGG+Y+F++ D Y+ SG  LL+L+FFECVSISW YGV
Sbjct: 167 KRKEIFIAIVCMLSYLVGLTCITQGGMYIFQILDSYAVSGFCLLWLIFFECVSISWCYGV 346

Query: 478 NRFYDNIQEMVGSRPCIWWKLCWSFFTPIIVAGVFLFSAVQMTPLTMGSYVFPKWGQGVG 537
           +RFYD I++M+G  P +WWK CW F TP I  GVF F+ VQ   +    Y +P W    G
Sbjct: 347 DRFYDGIKDMIGYYPTVWWKFCWCFTTPAICLGVFFFNIVQWKSIKYLDYSYPWWAHAFG 526

Query: 538 WLMAL 542
           W  AL
Sbjct: 527 WFTAL 541

 Score = 82.4 bits (202), Expect(2) = 2e-55,   Method: Compositional matrix adjust.
 Identities = 37/58 (63%), Positives = 48/58 (82%)
 Frame = +1

Query: 366 LAYPEAVTQLPISPLWAILFFSMLLMLGIDSQFCTVEGFITALVDEYPRLLRNRRELF 423
           L YP AV QLP SP+W+ LFF MLL++G+DSQFCT+EGFITA++DE+P+LLR  +  F
Sbjct: 10  LVYPSAVLQLPGSPMWSCLFFFMLLLIGLDSQFCTMEGFITAVIDEWPQLLRKTQRDF 183
>32211
          Length = 836

 Score =  206 bits (523), Expect = 3e-53,   Method: Compositional matrix adjust.
 Identities = 101/197 (51%), Positives = 138/197 (70%), Gaps = 2/197 (1%)
 Frame = -1

Query: 310 NSFHNNVYRDSIIVCCINSCTSMFAGFVIFSIVGFMAHVTKRSIADVAASGPGLAFLAYP 369
              H    +   + CC              SI+GFMA      +ADVA SGPGLAF+AYP
Sbjct: 590 QQVHPQRIQGQRVFCCDQHVHQFPGRLCHLSILGFMAVRQGLDVADVAESGPGLAFIAYP 411

Query: 370 EAVTQLPISPLWAILFFSMLLMLGIDSQFCTVEGFITALVDEYPRLLR--NRRELFIAAV 427
           EAV QLPI+PLW+++FF M+++LG+DSQF  VEGFITA+VD YPR+LR  +RRE+FIA +
Sbjct: 410 EAVAQLPIAPLWSVMFFVMVILLGLDSQFVGVEGFITAVVDLYPRVLRRGHRREVFIAII 231

Query: 428 CIVSYLIGLSNITQGGIYVFKLFDYYSASGMSLLFLVFFECVSISWFYGVNRFYDNIQEM 487
           C+++Y IGLS +T+GG+YVF+LFDYYSAS + +L + FFEC+++++ YGV+RFYDN++ M
Sbjct: 230 CVIAYFIGLSMVTEGGMYVFQLFDYYSASRI-VLVVAFFECITVAYVYGVDRFYDNLEMM 54

Query: 488 VGSRPCIWWKLCWSFFT 504
            G R     K+ W   T
Sbjct: 53  FGFRMGPLMKVSWMALT 3

 Score =  117 bits (292), Expect = 2e-26,   Method: Compositional matrix adjust.
 Identities = 54/112 (48%), Positives = 73/112 (65%)
 Frame = -2

Query: 228 CIWKGVGWTGKVVYFSATYPYIMLIILFFRGVTLPGAKEGILFYITPNFRKLSDSEVWLD 287
           CIWKG+  +GKV+YF+AT PY+++ +L  RGVTL GA  G+ +Y+ P + +L D +VW+D
Sbjct: 835 CIWKGIKSSGKVMYFTATTPYVLMFVLLIRGVTLEGASTGLKYYLLPEWSRLKDPQVWVD 656

Query: 288 AATQIFFXXXXXXXXXXXXXXYNSFHNNVYRDSIIVCCINSCTSMFAGFVIF 339
           A TQIFF              YN F +NV+RDS+    IN+ TS  AGFVIF
Sbjct: 655 AGTQIFFSYSISLGTLTALGSYNRFTHNVFRDSVCFAVINTFTSFLAGFVIF 500
>18526
          Length = 537

 Score =  194 bits (493), Expect = 9e-50,   Method: Compositional matrix adjust.
 Identities = 93/172 (54%), Positives = 125/172 (72%)
 Frame = -2

Query: 208 GQIRWPLAITLAIAWVLVYFCIWKGVGWTGKVVYFSATYPYIMLIILFFRGVTLPGAKEG 267
           G +RW L ITLA++W+ V+ C++KGV   GKV++F+A +PY++L++L  RGVTLPGA +G
Sbjct: 530 GTVRWQLLITLAVSWLCVFLCLFKGVKVLGKVMHFAAPFPYMVLLVLLIRGVTLPGAIDG 351

Query: 268 ILFYITPNFRKLSDSEVWLDAATQIFFXXXXXXXXXXXXXXYNSFHNNVYRDSIIVCCIN 327
           I FYI P + KL + +VW DAA QIF+              YN F+NNVYRD++IV  IN
Sbjct: 350 ISFYIIPRWEKLLEFQVWGDAALQIFYSVGMAWGGIITMASYNKFNNNVYRDAMIVPLIN 171

Query: 328 SCTSMFAGFVIFSIVGFMAHVTKRSIADVAASGPGLAFLAYPEAVTQLPISP 379
             TS+FAGFVIFSI+GFMAH   +++ D+   GPGL F+AYPEAV++LPISP
Sbjct: 170 CGTSIFAGFVIFSILGFMAHEAGKNVEDIVTQGPGLTFVAYPEAVSKLPISP 15
>14556
          Length = 552

 Score =  153 bits (386), Expect = 2e-37,   Method: Compositional matrix adjust.
 Identities = 72/142 (50%), Positives = 96/142 (67%), Gaps = 3/142 (2%)
 Frame = -2

Query: 35  QKKAGDLPDRDTWKGRFDFLMSCVGYAIGLGNVWRFPYLCGKNGGGAFLIPYFLTLIFAG 94
            K   +  +R  W  + DFL+SCVGYA+GLGNVWRFPYL  +NGG  FL PY + LI AG
Sbjct: 446 SKMGSEDIERGNWGSQLDFLLSCVGYAVGLGNVWRFPYLAYRNGGATFLFPYIIMLIIAG 267

Query: 95  VPLFLLECSLGQYTSIGGLGVWKLAPMFKGVGLAAAVLSFWLNIYYIVIISWAIYYLYNS 154
           +PLF LE +LGQ+ S G + VWK++P F G+G A  ++S  ++IYY VII++AIYY++ S
Sbjct: 266 LPLFFLELALGQFASEGPITVWKMSPFFSGIGFAMCIISGVVSIYYNVIITYAIYYMFVS 87

Query: 155 FT---TTLPWKQCDNPWNTDRC 173
           F      LPW  C++ W T  C
Sbjct: 86  FVNLDNDLPWASCNHTWATPSC 21
>26872
          Length = 406

 Score =  135 bits (340), Expect = 5e-32,   Method: Compositional matrix adjust.
 Identities = 64/134 (47%), Positives = 98/134 (73%)
 Frame = +2

Query: 363 LAFLAYPEAVTQLPISPLWAILFFSMLLMLGIDSQFCTVEGFITALVDEYPRLLRNRREL 422
           L F+AYPEA++ LP +  WA++FF MLL LG+DS F   E  ITAL DE+P +LR  REL
Sbjct: 2   LVFVAYPEAISTLPGASFWAVIFFLMLLTLGLDSSFGGSEAIITALSDEFP-VLRRHREL 178

Query: 423 FIAAVCIVSYLIGLSNITQGGIYVFKLFDYYSASGMSLLFLVFFECVSISWFYGVNRFYD 482
           F+ A+ ++ +++GL++  +GG+YV  L D + A+G S+LF VFFE +++SW YG++RF +
Sbjct: 179 FVLALFVLYFIVGLASCAEGGLYVVNLLDQF-AAGYSILFAVFFETLAVSWAYGLDRFSE 355

Query: 483 NIQEMVGSRPCIWW 496
           +++ M+G RP  +W
Sbjct: 356 DLEAMLGHRPGPYW 397
>02570
          Length = 1067

 Score =  135 bits (339), Expect = 6e-32,   Method: Compositional matrix adjust.
 Identities = 81/238 (34%), Positives = 129/238 (54%), Gaps = 10/238 (4%)
 Frame = -3

Query: 365  FLAYPEAVTQLPISPLWAILFFSMLLMLGIDSQFCTVEGFITALVDEYPRLLRNRRELFI 424
            F+AYPEA++ LP   LW++LFF ML  LG+DS+F  +E  +T + DE PR  R  + +  
Sbjct: 1065 FVAYPEALSNLPPPQLWSVLFFFMLFTLGLDSEFGLMETILTCIQDEMPR-XRKYKSVMC 889

Query: 425  AAVCIVSYLIGLSNITQGGIYVFKLFDYYSASGMSLLFLVFFECVSISWFYGVNRFYDNI 484
                I  Y + L  +  GG YV  L D+Y A   S+L L  FE +S+ W YGV RF  ++
Sbjct: 888  IGFGIGCYFLALPCVCNGGDYVVTLMDHYGAD-FSVLILSCFEVMSVMWXYGVMRFQKDL 712

Query: 485  QEMVGSRPCIW--WKLCWSFFTPIIVAGVFLFSAVQMTPLTMGS---YVFPKWGQGVGWL 539
            + M+G RP  W  W  CWS   PI++A +FL+  V+  P    S   + +P++ Q +GW 
Sbjct: 711  EYMLGRRPMGWPYWVFCWS-IAPILIAALFLYRMVEYVPPHYDSEKLHPYPQFAQNIGWF 535

Query: 540  MALSSMVLIPGYMAYMFLTL-----KGSLKQRLQVMIQPSEDIVRPENGPEQPQAGSS 592
            + +  +  IP +  Y  +          + + + +M +P+++  RP +G ++   G S
Sbjct: 534  LLVVVLCPIPLWFIYHAVRTYRQNSDQPISEIIAIMFRPTKEW-RPADGSDRYLVGDS 364
>19604
          Length = 419

 Score =  130 bits (326), Expect = 2e-30,   Method: Compositional matrix adjust.
 Identities = 62/133 (46%), Positives = 89/133 (66%)
 Frame = -3

Query: 208 GQIRWPLAITLAIAWVLVYFCIWKGVGWTGKVVYFSATYPYIMLIILFFRGVTLPGAKEG 267
           G  RW LA+ L ++WV+V  C+ KG+  +GKVVYF+AT+PY++LIIL  RG  L GAKEG
Sbjct: 399 GTPRWRLALCLLLSWVVVILCLIKGIKSSGKVVYFTATFPYVILIILLIRGALLEGAKEG 220

Query: 268 ILFYITPNFRKLSDSEVWLDAATQIFFXXXXXXXXXXXXXXYNSFHNNVYRDSIIVCCIN 327
           + F+I P + KL+D +VW+ AA Q+FF              YN F NNVY D++++  ++
Sbjct: 219 VEFFIIPEWDKLTDVKVWVAAAGQMFFSLSVSFGGIIMFGSYNKFTNNVYGDALLISVMD 40

Query: 328 SCTSMFAGFVIFS 340
             TS+ AGFV+F+
Sbjct: 39  LVTSVIAGFVVFT 1
>26038
          Length = 426

 Score =  114 bits (284), Expect = 1e-25,   Method: Compositional matrix adjust.
 Identities = 56/130 (43%), Positives = 87/130 (66%), Gaps = 2/130 (1%)
 Frame = -2

Query: 381 WAILFFSMLLMLGIDSQFCTVEGFITALVDEYPRLLRNR--RELFIAAVCIVSYLIGLSN 438
           WAI+FF MLL LGIDS F  +E  +T L DE   ++R R  RE+    V   ++   L  
Sbjct: 416 WAIIFFFMLLTLGIDSAFGGLESPLTGLHDELKTVMRMRYSREVLTLVVVGSAFFCSLPC 237

Query: 439 ITQGGIYVFKLFDYYSASGMSLLFLVFFECVSISWFYGVNRFYDNIQEMVGSRPCIWWKL 498
           +T+GGIYVF + D ++A G S+LF V  + +++SWFYG+N+F  ++++M GS+P ++W++
Sbjct: 236 LTEGGIYVFTILDTFAA-GTSILFTVLCQVIAVSWFYGINQFCRDVEKMTGSQPSMYWRV 60

Query: 499 CWSFFTPIIV 508
           CW F  PI++
Sbjct: 59  CWKFVCPILL 30
>33291
          Length = 467

 Score = 75.1 bits (183), Expect(2) = 9e-20,   Method: Composition-based stats.
 Identities = 35/64 (54%), Positives = 42/64 (65%)
 Frame = -1

Query: 313 HNNVYRDSIIVCCINSCTSMFAGFVIFSIVGFMAHVTKRSIADVAASGPGLAFLAYPEAV 372
            NN  RDSIIV  IN  TS +AGF IFSI+GFMA      + DV   G GL F+AYPEA+
Sbjct: 332 QNNAIRDSIIVPIINCLTSFYAGFAIFSILGFMAASKGVEVEDVTTDGTGLVFVAYPEAL 153

Query: 373 TQLP 376
            ++P
Sbjct: 152 ARMP 141

 Score = 40.0 bits (92), Expect(2) = 9e-20,   Method: Compositional matrix adjust.
 Identities = 19/48 (39%), Positives = 22/48 (45%)
 Frame = -2

Query: 268 ILFYITPNFRKLSDSEVWLDAATQIFFXXXXXXXXXXXXXXYNSFHNN 315
           I FY+ P+  KLS+S VWL AA QIFF              Y  F   
Sbjct: 466 IKFYLQPDASKLSESSVWLAAAAQIFFSLSTSTGSLTAMSSYTKFKTT 323

 Score = 42.0 bits (97), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 25/64 (39%), Positives = 35/64 (54%)
 Frame = -3

Query: 360 GPGLAFLAYPEAVTQLPISPLWAILFFSMLLMLGIDSQFCTVEGFITALVDEYPRLLRNR 419
           GPG+  L  P    Q  +  LW++LFF M++ LG+ +Q  + E  +TAL DEY  L  N 
Sbjct: 186 GPGVCGL--P*GAGQDALPQLWSVLFFFMMICLGMGTQIPSAETLLTALQDEYKCLRGNG 13

Query: 420 RELF 423
              F
Sbjct: 12  APSF 1
>25926
          Length = 675

 Score = 82.8 bits (203), Expect = 4e-16,   Method: Compositional matrix adjust.
 Identities = 39/104 (37%), Positives = 58/104 (55%), Gaps = 4/104 (3%)
 Frame = +1

Query: 475 YGVNRFYDNIQEMVGSRPCIWWKLCWSFFTPIIVAGVFLFSAVQMTPLTMG----SYVFP 530
           YGVNRFYDN++ M G R   W K+CW+  TP+    +F+   +  + LT      +Y +P
Sbjct: 7   YGVNRFYDNLEMMFGFRVGPWMKICWTVLTPLYTMVIFIMGCISYSDLTYKRKTVTYEYP 186

Query: 531 KWGQGVGWLMALSSMVLIPGYMAYMFLTLKGSLKQRLQVMIQPS 574
            W  GVGW M   S++ IP  M +  LT  GS  +R++ + +P 
Sbjct: 187 SWAIGVGWSMVAMSIIFIPLVMVFRMLTADGSFVERVKHLTKPR 318
>21870
          Length = 347

 Score = 78.2 bits (191), Expect = 9e-15,   Method: Composition-based stats.
 Identities = 33/56 (58%), Positives = 43/56 (76%)
 Frame = -2

Query: 44  RDTWKGRFDFLMSCVGYAIGLGNVWRFPYLCGKNGGGAFLIPYFLTLIFAGVPLFL 99
           R TW    +F+++C+G+A+GLGNVWRFPYLC +NGGGAFLIPY ++L F   P  L
Sbjct: 199 RATWGRHLEFIVTCIGFAVGLGNVWRFPYLCYRNGGGAFLIPYLISLGFHWHPSLL 32
>14638
          Length = 421

 Score = 73.6 bits (179), Expect = 2e-13,   Method: Compositional matrix adjust.
 Identities = 42/137 (30%), Positives = 70/137 (51%), Gaps = 6/137 (4%)
 Frame = -3

Query: 419 RRELFIAAVCIVSYLIGLSNITQGGIYVFKLFDYYSASGMSLLFLVFFECVSISWFYGVN 478
           R  +F  ++C + +++GL   TQGG Y+  L D +   G  LL + FFE V+I W YG  
Sbjct: 407 RSIIFRVSMCALGFILGLPQTTQGGTYILDLLDIFV--GFPLLLVGFFEFVAIVWVYGFR 234

Query: 479 RFYDNIQEMVGSRPC------IWWKLCWSFFTPIIVAGVFLFSAVQMTPLTMGSYVFPKW 532
           R  +++  M+G  P        ++   W   +P ++  + +F +V   P+T   Y  P W
Sbjct: 233 RISEDVMMMMGDHPITRMVYDFYFSWTWLVVSPGLLLAIIVFDSVNYVPITGPGY--PPW 60

Query: 533 GQGVGWLMALSSMVLIP 549
            + +GWL+    M+ IP
Sbjct: 59  AETLGWLVVTFIMMWIP 9
>31151
          Length = 322

 Score = 49.7 bits (117), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 28/78 (35%), Positives = 43/78 (55%)
 Frame = -2

Query: 472 SWFYGVNRFYDNIQEMVGSRPCIWWKLCWSFFTPIIVAGVFLFSAVQMTPLTMGSYVFPK 531
            W YGV R  ++I  M+G  P     + W F TP ++  V +F+ +  TP + G YV+  
Sbjct: 321 GWIYGVARIREDICLMLGHGPPFILTVFWKFITPALLLVVLVFTLMNYTPPSYGQYVYGT 142

Query: 532 WGQGVGWLMALSSMVLIP 549
            G   GW++ALSS++  P
Sbjct: 141 GGHVFGWVVALSSLLPSP 88
>00472
          Length = 2194

 Score = 30.8 bits (68), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 21/80 (26%), Positives = 34/80 (42%)
 Frame = +2

Query: 179 LVNTTNMTSAVVEFWERNMHQMTDGLDKPGQIRWPLAITLAIAWVLVYFCIWKGVGWTGK 238
           L  TT++++       R+M+  T    K GQI + L + L +     + C W   G    
Sbjct: 341 LSRTTSISAHSASLHNRSMYDSTGSFLKSGQIHYMLCVHLXMILKSXFNCSWDYGG---- 508

Query: 239 VVYFSATYPYIMLIILFFRG 258
              F + Y  ++L  L F G
Sbjct: 509 ---FFSIYXKVLLAFLTFIG 559
>11578
          Length = 559

 Score = 28.5 bits (62), Expect = 8.8,   Method: Composition-based stats.
 Identities = 13/42 (30%), Positives = 19/42 (45%), Gaps = 3/42 (7%)
 Frame = -2

Query: 161 WKQCDNPW---NTDRCFSNYSLVNTTNMTSAVVEFWERNMHQ 199
           W QCD PW   + DRC S   +  +  + +      + N HQ
Sbjct: 510 WVQCDTPWQDGSADRCSSGVGICMSAQLRTLFSICTQFNKHQ 385
>10280
          Length = 2352

 Score = 28.1 bits (61), Expect = 9.9,   Method: Compositional matrix adjust.
 Identities = 16/53 (30%), Positives = 27/53 (50%), Gaps = 1/53 (1%)
 Frame = -2

Query: 177 YSLVNTTNMTSAVVEFWERNMHQMTDG-LDKPGQIRWPLAITLAIAWVLVYFC 228
           +S+ N+    S V   W R   +  DG   +P Q  + L++ L  +WV +Y+C
Sbjct: 647 WSVANSFKDLSIVPWKWARERGRPVDGSARRPCQRYFALSLFLVESWVFIYWC 489
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|51491852|ref|NP_001003913.1| methionine-tRNA
synthetase [Mus musculus]
         (902 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

14979                                                                 505   e-143
04150                                                                 293   3e-79
00661                                                                  29   6.7  
>14979
          Length = 1133

 Score =  505 bits (1301), Expect = e-143,   Method: Compositional matrix adjust.
 Identities = 228/328 (69%), Positives = 269/328 (82%)
 Frame = -1

Query: 238 AVAAWEKGLESLPPLKLQQHPVLPVPGERNVLITSALPYVNNVPHLGNIIGCVLSADVFA 297
           AV AW    +  P    ++HPVLP   +RN+LITSALPYVNNVPHLGNIIGCVLSADVF+
Sbjct: 986 AVKAWNTSNKDFPVPSPRKHPVLPKKNKRNILITSALPYVNNVPHLGNIIGCVLSADVFS 807

Query: 298 RYCRLRQWNTLYLCGTDEYGTATETKAMEEGLTPREICDKYHAIHADIYRWFGISFDTFG 357
           R+CRLR +N LY+CGTDEYGTATETKA+EEG+TP++ICDKY+ +H +IY+WF I FD FG
Sbjct: 806 RFCRLRNYNVLYVCGTDEYGTATETKALEEGVTPQQICDKYNKLHTEIYQWFNIDFDYFG 627

Query: 358 RTTTPQQTKITQDIFQRLLTRGFVLRDTVEQLRCERCARFLADRFVEGVCPFCGYEEARG 417
           RTTTPQQT+I QDIF RL  RGF+L+D++EQL C  C +FLADRFVEGVCP CG+E+ARG
Sbjct: 626 RTTTPQQTEIAQDIFWRLHERGFILKDSMEQLHCGSCDKFLADRFVEGVCPLCGFEDARG 447

Query: 418 DQCDRCGKLINAIELKKPQCKICRSCPVVRSSQHLFLDLPKLEKRLEDWLGKTVPGSDWT 477
           DQCD CGKLINA ELK P+CKICR  P  R SQHLFLDLPKLE  L+  L K      WT
Sbjct: 446 DQCDGCGKLINATELKDPKCKICRKAPSPRISQHLFLDLPKLEGDLKSHLDKAFGEGTWT 267

Query: 478 PNARFIIRSWLRDGLKPRCITRDLKWGTPVPLEGFEDKVFYVWFDATIGYVSITANYTDQ 537
            N+R I  SW+RDGLKPRCI+RDLKWGTPVPLEG++DKVFYVWFDA IGY+SITANYTBQ
Sbjct: 266 TNSRTITNSWIRDGLKPRCISRDLKWGTPVPLEGYKDKVFYVWFDAPIGYISITANYTBQ 87

Query: 538 WEKWWKNPEQVDLYQFMAKDNVPFHGLV 565
           W++WW NP+QV++Y F+ KDNVPFH ++
Sbjct: 86  WKQWWNNPKQVEMYNFLGKDNVPFHSVI 3
>04150
          Length = 1425

 Score =  293 bits (749), Expect = 3e-79,   Method: Compositional matrix adjust.
 Identities = 156/294 (53%), Positives = 198/294 (67%), Gaps = 20/294 (6%)
 Frame = -1

Query: 602  IGVFGDMAKDTGIPADIWRFYLLYIRPEGQDSAFSWTDLLIKNNSELLNNLGNFINRAGM 661
            +GVFGD AKDTGIPADI+RFYLLY+RPE QD++FSW DLL+KNNSELLNNLGNFINRA M
Sbjct: 1425 VGVFGDQAKDTGIPADIYRFYLLYVRPESQDTSFSWDDLLLKNNSELLNNLGNFINRALM 1246

Query: 662  FVSKFFGGCVPEMALTPDDRRLVAHVSWELQHYHQLLEKVRIRDALRSILTISRHGNQYI 721
            F+S  FGG V EM L  DD++L+A V+ EL+ Y   +E  R+RD++R+ILTISR GNQ++
Sbjct: 1245 FLSNNFGGVVQEMNLQDDDKQLLALVTRELRSYVDNMEHGRLRDSIRNILTISRLGNQFM 1066

Query: 722  QVNEPWKRIKGGEMDRQRAGTVTGMAVNMAALLSVMLQPYMPTVSSTIQTQLQLPPAACR 781
            Q N+PW  +KG   D++RAG V  ++ N++ LLSV+LQPYMP VS+TIQ QL   PA   
Sbjct: 1065 QANKPWVLVKGTAEDKKRAGVVVSVSANVSCLLSVLLQPYMPAVSATIQEQLN-APADVN 889

Query: 782  ILATSFICTLPAGHRIGTVSPLFQKLENDQIENLRQRFGGGQAKGSPKPA---------- 831
            ++  +FIC L  GH+IG  SPLFQK+E   I +L+ +F G  A   PKPA          
Sbjct: 888  VVTETFICRLWPGHKIGKPSPLFQKIEASTIADLKAKFAGKPA--PPKPADKAKGAAASG 715

Query: 832  ----------AVEAVTAAGSQHIQTLTDEVTKQGNVVRELKAQKADKNQVAAEV 875
                      A           +  LT+EVT QGN VRE+KA KADK  + A+V
Sbjct: 714  AGNKGSGESSANGPXGVVNEAEVARLTEEVTAQGNKVREVKAAKADKATIDAQV 553
>00661
          Length = 2118

 Score = 29.3 bits (64), Expect = 6.7,   Method: Compositional matrix adjust.
 Identities = 13/42 (30%), Positives = 20/42 (47%)
 Frame = +3

Query: 419 QCDRCGKLINAIELKKPQCKICRSCPVVRSSQHLFLDLPKLE 460
           +C  CG+  N +  K PQ    + C   +S QHL    P+ +
Sbjct: 279 RCYNCGEFSNHLAAKCPQGPAPKRCHHCKSEQHLIAQCPQRQ 404
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|125628629|ref|NP_061219.2| eukaryotic translation
initiation factor 3, subunit 7 (zeta) [Mus musculus]
         (548 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

01771                                                                 501   e-142
26500                                                                 167   1e-41
>01771
          Length = 1615

 Score =  501 bits (1290), Expect = e-142,   Method: Compositional matrix adjust.
 Identities = 237/377 (62%), Positives = 291/377 (77%), Gaps = 5/377 (1%)
 Frame = +3

Query: 156 KPRDSSVEVRSDWEVKEEMDFPQLMKMRYLEVSEPQDIECCGALEYYDKAFDRITTRSEK 215
           K RD+SV+++ DW V EEMDFP+L K+   +  E  D+  CG +E YDK +DR+TT++EK
Sbjct: 9   KHRDASVQIKDDWPVVEEMDFPRLTKLNLPDAKEAVDLMRCGGMEIYDKTYDRVTTKNEK 188

Query: 216 PLRSIKRIFHTVTTTDDPVIRKLAKTQGNVFATDAILATLMSCTRSVYSWDIVVQRVGSK 275
           PL+ I RIFH VTTTDDP+IR+LAKTQGNVFATDAILAT+M CTRS YSWDIV+QRVG+K
Sbjct: 189 PLKRINRIFHKVTTTDDPIIRQLAKTQGNVFATDAILATIMCCTRSSYSWDIVIQRVGNK 368

Query: 276 LFFDKRDNSDFDLLTVSETANEPPQDEGNSFNSPRNLAMEATYINHNFSQQCLRMGRERY 335
           LFFDKRD+SDFDLLTVSETA EPPQDEGNS NSPRNLA+EAT+INHNFSQQ L+ G ++Y
Sbjct: 369 LFFDKRDDSDFDLLTVSETATEPPQDEGNSINSPRNLALEATFINHNFSQQVLKPGEDKY 548

Query: 336 NFPNPNPFVEDDMDKNEIASVAYRYRRWKLGDDIDLIVRCEHDGVMTGANGEVSFINIKT 395
            F N NPFV+ + ++ ++ASV YRYR+W LG+DI LI RCEHD VM   N E  FI IK+
Sbjct: 549 KFENKNPFVQTE-EETDVASVGYRYRKWDLGNDIVLIARCEHDAVMYAXNNEAQFIXIKS 725

Query: 396 LNEWDSRHCNGVDWRQKLDSQRGAVIA--TELKNNSYKLARWTCCA---LLAGSEYLKLG 450
           LNEWDSRH  GV WR +LDSQR AV+A  T  + +S KLA+WT C    L     ++ + 
Sbjct: 726 LNEWDSRHSGGVXWRSRLDSQRXAVLATVTRAEKHSCKLAKWTVCHSCRLRPNQVWICIA 905

Query: 451 YVSRYHVKDSSRHVILGTQQFKPNEFASQINLSVENAWGILRCVIDICMKLEEGKYLILK 510
                H     +H ILGT QFKP EFA+QINL+++NAWGILRC++D CMKL+EGKYLI+K
Sbjct: 906 SACEGH----DKHXILGTXQFKPTEFAAQINLNMDNAWGILRCIVDTCMKLKEGKYLIMK 1073

Query: 511 DPNKQVIRVYSLPDGTF 527
           DPNK V+ +Y +PD TF
Sbjct: 1074DPNKPVVXIYDIPDHTF 1124
>26500
          Length = 435

 Score =  167 bits (422), Expect = 1e-41,   Method: Compositional matrix adjust.
 Identities = 85/139 (61%), Positives = 104/139 (74%), Gaps = 1/139 (0%)
 Frame = -3

Query: 1   MAKFMTPVIQDNPSGWGPCAVPEQFRDMPYQPFSKGDRLGKVADWTGATYQDKRYTNKYS 60
           MA+F  P IQDNP GWGPC +PE ++D+PYQPFSK  RLGKV+DWTGATYQDKRY  KY+
Sbjct: 415 MARFDPPQIQDNPEGWGPCVMPEMYKDLPYQPFSKDVRLGKVSDWTGATYQDKRYLGKYN 236

Query: 61  SQFGGGSQYAYFHEEDETSFQLVDTARTQKTAYQRNRMRFAQ-RNLRRDKDRRNMVQFNL 119
           S F GGSQYAY+HEEDE+SFQLVDTA+ Q+  YQR R  F Q +  R  + R+   Q N+
Sbjct: 235 SAF-GGSQYAYYHEEDESSFQLVDTAKVQRPIYQRGRRMFQQTKQRRERERRQQQAQANM 59

Query: 120 QTLPKSAKQKERERIRLQK 138
           Q L K+ K +ER+R R+ K
Sbjct: 58  QVLTKTQKNRERDRQRMLK 2
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|33468931|ref|NP_035449.1| seryl-aminoacyl-tRNA
synthetase [Mus musculus]
         (536 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

08633                                                                 496   e-141
11977                                                                 151   5e-37
33502                                                                  30   1.9  
37355                                                                  28   7.4  
>08633
          Length = 1845

 Score =  496 bits (1278), Expect = e-141,   Method: Compositional matrix adjust.
 Identities = 240/334 (71%), Positives = 268/334 (80%), Gaps = 1/334 (0%)
 Frame = +3

Query: 171 VDLVVMVDGFEGEKGAVVAGSRGYFLKGPLVFLEQALIQYALRTLGSRGYTPIYTPFFMR 230
           VDLVVMVDG + ++GAV AG RGY+LKGPLVFLEQALI +++  L  +GY P+YTPFFMR
Sbjct: 18  VDLVVMVDGVDMDRGAVAAGGRGYYLKGPLVFLEQALINHSMMMLYGKGYQPLYTPFFMR 197

Query: 231 KEVMQEVAQLSQFDEELYKVIGKGSEKSDD-NSYDEKYLIATSEQPIAALHRDEWLRPED 289
           KEVMQEVAQLSQFDEELYKVIGKGSEK ++ +  DEKYLIATSEQPIAA HRDEW+  E 
Sbjct: 198 KEVMQEVAQLSQFDEELYKVIGKGSEKKEEGDVVDEKYLIATSEQPIAAFHRDEWIATES 377

Query: 290 LPIKYAGLSTCFRQEVGSHGRDTRGIFRVHQFEKIEQFVYSSPHDNKSWEMFDEMIATAE 349
           LPI+Y G STCFRQEVGSHGRDTRGIFRVHQFEK+EQF  ++P DNKSWEMFDEMI  AE
Sbjct: 378 LPIRYLGYSTCFRQEVGSHGRDTRGIFRVHQFEKVEQFCITAPTDNKSWEMFDEMIGNAE 557

Query: 350 EFYQSLGIPYHIVNIVSGSLNHAASKKLDLEAWFPGSGAFRELVSCSNCTDYQARRLRIR 409
            F +SLGIPY +VNIVSG LN+AA+KKLDLEAWFPGS +FRELVSCSNCTDYQARRLRIR
Sbjct: 558 AFNKSLGIPYRVVNIVSGELNNAAAKKLDLEAWFPGSASFRELVSCSNCTDYQARRLRIR 737

Query: 410 YGQTKKMMDKKKNNLRFSTQNKLKAMSSLFSPKKVEFVHMLNATMCATTRTICAILENYQ 469
           YGQTKKM                         ++V +VHMLNATMCATTR ICAILEN Q
Sbjct: 738 YGQTKKM------------------------GQEVPYVHMLNATMCATTRVICAILENNQ 845

Query: 470 AEKGIAVPEKLREFMPPGLQELIPFVKPAPIDQE 503
            E G+ VPE LR FMP GL E IPFVKPAPID++
Sbjct: 846 TEDGVIVPEVLRRFMPEGLNEKIPFVKPAPIDEQ 947
>11977
          Length = 488

 Score =  151 bits (382), Expect = 5e-37,   Method: Compositional matrix adjust.
 Identities = 74/141 (52%), Positives = 103/141 (73%), Gaps = 1/141 (0%)
 Frame = +1

Query: 1   MVLDLDLFRVDKGGDPALIRETQEKRFKDPGLVDQLVKADSEWRRCRFRADNLNKLKNLC 60
           MVLD++LFR DKGGDP+ ++E Q KRFKD  LVD++V+ D+ WR+ RFRAD LNKLKN+C
Sbjct: 61  MVLDIELFRADKGGDPSKVKENQAKRFKDVTLVDKVVEKDTAWRKLRFRADLLNKLKNVC 240

Query: 61  SKTIGEKMKKKEAVGDDESVPENV-LNFXXXXXXXXXXXKVSQIKKVRLLIDEAIQKCDG 119
           S  IG+KMKKKE VG+DE++P+++  N             V+QIK++RLLID+ ++    
Sbjct: 241 SNEIGDKMKKKEPVGEDETIPDDIRTNIDDLNQEKLKALTVTQIKQIRLLIDQQMKDNSQ 420

Query: 120 ERVKLEAERFENLREIGNLLH 140
             ++ EA R ++LREIGN+LH
Sbjct: 421 ALLETEAARNQSLREIGNMLH 483
>33502
          Length = 1173

 Score = 30.4 bits (67), Expect = 1.9,   Method: Compositional matrix adjust.
 Identities = 10/38 (26%), Positives = 24/38 (63%)
 Frame = -1

Query: 336 KSWEMFDEMIATAEEFYQSLGIPYHIVNIVSGSLNHAA 373
           K  E++D +  + + F+Q++  P+H++ ++   L+H A
Sbjct: 129 KLLELYDRLFKSRDPFWQTVRKPHHLLTVLHALLSHLA 16
>37355
          Length = 676

 Score = 28.5 bits (62), Expect = 7.4,   Method: Compositional matrix adjust.
 Identities = 15/38 (39%), Positives = 24/38 (63%), Gaps = 1/38 (2%)
 Frame = +2

Query: 26  RFKDPG-LVDQLVKADSEWRRCRFRADNLNKLKNLCSK 62
           ++KD   L+++ V+    + RCR R  +LN LKN+ SK
Sbjct: 401 KYKDNNILMEKYVQQFKTYHRCRRRKTSLNLLKNMLSK 514
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|19527246|ref|NP_598789.1| tubulin, gamma 2 [Mus
musculus]
         (451 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

05902                                                                 493   e-140
16482                                                                 170   9e-43
00276                                                                 142   3e-34
12457                                                                 125   2e-29
04882                                                                 112   4e-25
13181                                                                 111   5e-25
06360                                                                  90   2e-18
39157                                                                  86   2e-17
03702                                                                  85   6e-17
25015                                                                  75   5e-14
28905                                                                  58   7e-09
30297                                                                  29   3.3  
01993                                                                  29   4.1  
33626                                                                  28   7.5  
>05902
          Length = 1127

 Score =  493 bits (1270), Expect = e-140,   Method: Compositional matrix adjust.
 Identities = 245/296 (82%), Positives = 268/296 (90%)
 Frame = +2

Query: 155 ERLNDRYPKKLVQTYSVFPNQDEMSDVVVQPYNSLLTLKRLTQNADCVVVLDNTALNRIA 214
           E+LNDR+PKKL+QTYSVFPN DE+SDVVVQPYNSLLTLKRLTQNADCVVVLDNTALNRIA
Sbjct: 71  EKLNDRFPKKLIQTYSVFPNVDEISDVVVQPYNSLLTLKRLTQNADCVVVLDNTALNRIA 250

Query: 215 TDRLHIQNPSFSQINQLVSTIMSASTTTLRYPGYMNNDLIGLIASLIPTPRLHFLMTGYT 274
            DRLHI  P+F+Q+NQLVST+MS STTTLRYPGYMNNDLIGLIASLIPTPRLHFLMTGYT
Sbjct: 251 ADRLHIDTPTFAQVNQLVSTVMSTSTTTLRYPGYMNNDLIGLIASLIPTPRLHFLMTGYT 430

Query: 275 PLTTDQSVASVRKTTVLDVMRRLLQPKNVMVSTGRDRQTNHCYIAILNIIQGEVDPTQVH 334
           PLTTD  VA+VRKTTVLDVMRRLLQPKN+MVST   RQ NHCYI+ILNIIQGEVDPTQVH
Sbjct: 431 PLTTDSQVANVRKTTVLDVMRRLLQPKNMMVSTPVHRQANHCYISILNIIQGEVDPTQVH 610

Query: 335 KSLQRIRERKLANFIPWGPASIQVALSRKSPYLPSAHRVSGLMMANHTSISSLFESSCQQ 394
           KSLQRIRERKLA FIPWGPASIQVALSRKSPY+ +AHRVSGLM+ANHTSIS LFE   +Q
Sbjct: 611 KSLQRIRERKLAQFIPWGPASIQVALSRKSPYVQTAHRVSGLMLANHTSISHLFERILRQ 790

Query: 395 YDKLWKRGAFLEQFRKEDIFKDNFEEMHRSREVVQELIDEYHAATRPDYISWGTQE 450
           YDKL KR AF++QF+KE IFKDN +E   SRE +Q L+DEY AATR DY+SWGTQ+
Sbjct: 791 YDKLRKREAFMDQFKKEAIFKDNLDEFDNSREALQLLVDEYQAATRRDYLSWGTQQ 958
>16482
          Length = 837

 Score =  170 bits (431), Expect = 9e-43,   Method: Compositional matrix adjust.
 Identities = 82/247 (33%), Positives = 139/247 (56%)
 Frame = +1

Query: 3   REIITLQLGQCGNQIGFEFWKQLCAEHGISPEGIVEEFATEGTDRKDVFFYQADDEHYIP 62
           REI+ +Q GQCGNQIG +FW+ +  EHGI P G     +    +R +V++ +A    Y+P
Sbjct: 103 REIVHMQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEATGGKYVP 282

Query: 63  RAVLLDLEPRVIHSILNSSYAKLYNPENIYLSEHXXXXXXXXXXXFSQGEKIHEDIFDII 122
           RAVL+DLEP  + S+ +  + +++ P+N    +            +++G ++ + + D++
Sbjct: 283 RAVLVDLEPGTMDSVRSGPFGQIFRPDNFVFGQ-SGAGNNWAKGHYTEGAELVDSVLDVV 459

Query: 123 DREADGSDSLEGFVLCHXXXXXXXXXXXXXXXERLNDRYPKKLVQTYSVFPNQDEMSDVV 182
            +EA+  D L+GF L H                ++ + YP +++ T+SV P+  ++SD V
Sbjct: 460 RKEAESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVVPSP-KVSDTV 636

Query: 183 VQPYNSLLTLKRLTQNADCVVVLDNTALNRIATDRLHIQNPSFSQINQLVSTIMSASTTT 242
           V+PYN+ L++ +L +N D    +DN AL  I    L +  P++  +N LVS  MS  TT 
Sbjct: 637 VEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTC 816

Query: 243 LRYPGYM 249
           LR+PG +
Sbjct: 817 LRFPGQL 837
>00276
          Length = 1330

 Score =  142 bits (358), Expect = 3e-34,   Method: Compositional matrix adjust.
 Identities = 85/333 (25%), Positives = 170/333 (51%), Gaps = 5/333 (1%)
 Frame = -3

Query: 108  FSQGEKIHEDIFDIIDREADGSDSLEGFVLCHXXXXXXXXXXXXXXXERLNDRYPKKLVQ 167
            ++ G+++ + + D I + AD    L+GF++ H               ERL+  Y KK   
Sbjct: 1247 YTIGKELVDLVLDRIRKLADQCTGLQGFLIFHSFGGGTGSGFTSLXMERLSVDYGKKSKL 1068

Query: 168  TYSVFPNQDEMSDVVVQPYNSLLTLKRLTQNADCVVVLDNTALNRIATDRLHIQNPSFSQ 227
             + ++P   ++S  VV+PYNS+LT     +++DC  ++DN A+  I    L I+ P+++ 
Sbjct: 1067 EFXIYP-APQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTN 891

Query: 228  INQLVSTIMSASTTTLRYPGYMNNDLIGLIASLIPTPRLHFLMTGYTPLTTDQSVASVRK 287
            +N+L+  I+S+ T +LR+ G +N DL     +L+P PR+HF +  Y P+ + +  A   +
Sbjct: 890  LNRLIXQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEK-AYHEQ 714

Query: 288  TTVLDVMRRLLQPKNVMVSTGRDRQTNHCYIAILNIIQGEVDPTQVHKSLQRIRERKLAN 347
              V ++     +P N +V           Y+A   + +G+V P  V+ ++  I+ ++   
Sbjct: 713  LXVAEITNACFEPANQLVKCDPRHGK---YMACCMLYRGDVVPKDVNAAIATIKTKRTIQ 543

Query: 348  FIPWGPASIQVALSRKSPYLPSAHRVSGL-----MMANHTSISSLFESSCQQYDKLWKRG 402
            F+ W P   +V ++ + P +     ++ +     M++N T+I+  +     ++D ++ + 
Sbjct: 542  FVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKR 363

Query: 403  AFLEQFRKEDIFKDNFEEMHRSREVVQELIDEY 435
            AF+  +  E + +  F E   +RE +  L  +Y
Sbjct: 362  AFVHWYVGEGMEEGEFSE---AREDLAALEKDY 273
>12457
          Length = 781

 Score =  125 bits (315), Expect = 2e-29,   Method: Compositional matrix adjust.
 Identities = 71/240 (29%), Positives = 129/240 (53%)
 Frame = -1

Query: 66  LLDLEPRVIHSILNSSYAKLYNPENIYLSEHXXXXXXXXXXXFSQGEKIHEDIFDIIDRE 125
           L+DLEP V+  +   +Y +L++PE + ++             ++ G++I + + D I + 
Sbjct: 718 LVDLEPTVVDEVRTGTYRQLFHPEQL-VTGKEDAANNYARGHYTIGKEIVDLVLDRIRKL 542

Query: 126 ADGSDSLEGFVLCHXXXXXXXXXXXXXXXERLNDRYPKKLVQTYSVFPNQDEMSDVVVQP 185
           AD    L+GF++ H               ERL+  Y KK    ++++P   ++S  VV+P
Sbjct: 541 ADQCTGLQGFLIFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFAIYP-APQVSTAVVEP 365

Query: 186 YNSLLTLKRLTQNADCVVVLDNTALNRIATDRLHIQNPSFSQINQLVSTIMSASTTTLRY 245
           YNS+LT     +++DC  ++DN A+  I    L I+ P+++ +N+L+  I+S+ T +LR+
Sbjct: 364 YNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLRF 185

Query: 246 PGYMNNDLIGLIASLIPTPRLHFLMTGYTPLTTDQSVASVRKTTVLDVMRRLLQPKNVMV 305
            G +N DL     +L+P PR+HF +  Y P+ + +  A   + TV ++     +P N MV
Sbjct: 184 DGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEK-AYHEQLTVAEITNACFEPANQMV 8
>04882
          Length = 1136

 Score =  112 bits (279), Expect = 4e-25,   Method: Compositional matrix adjust.
 Identities = 63/221 (28%), Positives = 114/221 (51%), Gaps = 4/221 (1%)
 Frame = +2

Query: 220 IQNPSFSQINQLVSTIMSASTTTLRYPGYMNNDLIGLIASLIPTPRLHFLMTGYTPLTTD 279
           +  P++  +N LVS  MS  TT LR+PG +N DL  L  +++P PRLHF M G+ PLT+ 
Sbjct: 314 VHTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSR 493

Query: 280 QSVASVRKTTVLDVMRRLLQPKNVMVST----GRDRQTNHCYIAILNIIQGEVDPTQVHK 335
            S    R  TV ++ +++   KN+M +     GR       Y+ +  I +G +   +V +
Sbjct: 494 GS-QQYRALTVPELTQQMFDSKNMMAACDPRHGR-------YLTVAAIFRGRMSMKEVDE 649

Query: 336 SLQRIRERKLANFIPWGPASIQVALSRKSPYLPSAHRVSGLMMANHTSISSLFESSCQQY 395
            +  ++ +  + F+ W P +++ A+       P   ++S   + N T+I  LF+   +Q+
Sbjct: 650 QMLNVQNKNSSYFVEWIPNNVKTAVCDIP---PRGLKMSATFIGNSTAIQELFKRISEQF 820

Query: 396 DKLWKRGAFLEQFRKEDIFKDNFEEMHRSREVVQELIDEYH 436
             +++R AFL  +  E + +  F E   +   + +L+ EY 
Sbjct: 821 TAMFRRKAFLHWYTGEGMDEMEFTEAESN---MNDLVSEYQ 934
>13181
          Length = 1092

 Score =  111 bits (278), Expect = 5e-25,   Method: Compositional matrix adjust.
 Identities = 63/223 (28%), Positives = 115/223 (51%), Gaps = 4/223 (1%)
 Frame = -3

Query: 218  LHIQNPSFSQINQLVSTIMSASTTTLRYPGYMNNDLIGLIASLIPTPRLHFLMTGYTPLT 277
            L +  P++  +N LVS  MS  TT LR+PG +N DL  L  +++P PRLHF M G+ PLT
Sbjct: 1069 LKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLT 890

Query: 278  TDQSVASVRKTTVLDVMRRLLQPKNVMVST----GRDRQTNHCYIAILNIIQGEVDPTQV 333
            +  S    R  TV ++ +++   KN+M +     GR       Y+ +  + +G +   +V
Sbjct: 889  SRGS-QQYRALTVPELTQQMFDAKNMMAACDPRHGR-------YLTVAAMFRGRMSMKEV 734

Query: 334  HKSLQRIRERKLANFIPWGPASIQVALSRKSPYLPSAHRVSGLMMANHTSISSLFESSCQ 393
             + +  ++ +  + F+ W P +++ A+       P   ++S   + N T+I  LF+   +
Sbjct: 733  DEQMLNVQNKNSSYFVEWIPNNVKTAVCDIP---PRGLKMSATFVGNSTAIQELFKRISE 563

Query: 394  QYDKLWKRGAFLEQFRKEDIFKDNFEEMHRSREVVQELIDEYH 436
            Q+  +++R AFL  +  E + +  F E   +   + +L+ EY 
Sbjct: 562  QFTAMFRRKAFLHWYTGEGMDEMEFTEAESN---MNDLVSEYQ 443
>06360
          Length = 1896

 Score = 89.7 bits (221), Expect = 2e-18,   Method: Compositional matrix adjust.
 Identities = 51/173 (29%), Positives = 87/173 (50%), Gaps = 2/173 (1%)
 Frame = -1

Query: 3    REIITLQLGQCGNQIGFEFWKQLCAEHGISPEGIVEEFAT--EGTDRKDVFFYQADDEHY 60
            RE I++ +GQ G Q+G   W+  C EHGI P+G +    T   G D  + FF +     +
Sbjct: 1707 RECISVHVGQAGVQMGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGKH 1528

Query: 61   IPRAVLLDLEPRVIHSILNSSYAKLYNPENIYLSEHXXXXXXXXXXXFSQGEKIHEDIFD 120
            +PRAV +DLEP V+  +   +Y +L++PE + ++             ++ G++I + + D
Sbjct: 1527 VPRAVFVDLEPTVVDEVRTGTYRQLFHPEQL-VTGKEDAANNYARGHYTIGKEIVDLVLD 1351

Query: 121  IIDREADGSDSLEGFVLCHXXXXXXXXXXXXXXXERLNDRYPKKLVQTYSVFP 173
             I + AD    L+GF++ H               ERL+  Y KK    ++++P
Sbjct: 1350 RIRKLADQCTGLQGFLIFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFAIYP 1192
>39157
          Length = 488

 Score = 86.3 bits (212), Expect = 2e-17,   Method: Compositional matrix adjust.
 Identities = 41/126 (32%), Positives = 68/126 (53%), Gaps = 2/126 (1%)
 Frame = -1

Query: 3   REIITLQLGQCGNQIGFEFWKQLCAEHGISPEGIVEEFATEGTDRKDVFFYQADDEHYIP 62
           REI+ LQ GQCGNQIG +FW+ +  EHGI P G     +    +R +V++ +A    Y+P
Sbjct: 440 REIVHLQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEATGGKYVP 261

Query: 63  RAVLLDLEPRVIHSILNSS--YAKLYNPENIYLSEHXXXXXXXXXXXFSQGEKIHEDIFD 120
           RAVL+DLEP  + S+ + S    K++ P+N    +              +G ++ + + D
Sbjct: 260 RAVLVDLEPGTMDSVRSGSPFGPKIFRPDNFVFGQSGAGNNWGQKDTTQRGAELVDSVLD 81

Query: 121 IIDREA 126
           ++ +  
Sbjct: 80  VVRKRG 63
>03702
          Length = 1932

 Score = 85.1 bits (209), Expect = 6e-17,   Method: Compositional matrix adjust.
 Identities = 50/151 (33%), Positives = 83/151 (54%)
 Frame = +1

Query: 155  ERLNDRYPKKLVQTYSVFPNQDEMSDVVVQPYNSLLTLKRLTQNADCVVVLDNTALNRIA 214
            ERL+  Y KK    ++++P   ++S  VV+PYNS+LT     +++DC  ++DN A+  I 
Sbjct: 1459 ERLSVDYGKKSKLEFAIYP-APQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDIC 1635

Query: 215  TDRLHIQNPSFSQINQLVSTIMSASTTTLRYPGYMNNDLIGLIASLIPTPRLHFLMTGYT 274
               L I+ P ++ +N+L+  I+S+ T +LR+ G +N DL     +L+PTP  H L  G+ 
Sbjct: 1636 RRNLDIERPXYTNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNLVPTP--HPLPPGHL 1809

Query: 275  PLTTDQSVASVRKTTVLDVMRRLLQPKNVMV 305
                    A   + TV +V     +P N +V
Sbjct: 1810 CPVISAEKAYHEQLTVAEVTNACFEPANQLV 1902
>25015
          Length = 458

 Score = 75.1 bits (183), Expect = 5e-14,   Method: Compositional matrix adjust.
 Identities = 34/119 (28%), Positives = 65/119 (54%)
 Frame = -3

Query: 21  FWKQLCAEHGISPEGIVEEFATEGTDRKDVFFYQADDEHYIPRAVLLDLEPRVIHSILNS 80
           FW+ +  EHGI P G     +    +R +V++ +A    Y+PRAVL+DLEP  + S+ + 
Sbjct: 363 FWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEATGGKYVPRAVLVDLEPGTMDSVRSG 184

Query: 81  SYAKLYNPENIYLSEHXXXXXXXXXXXFSQGEKIHEDIFDIIDREADGSDSLEGFVLCH 139
            + +++ P+N    +            +++G ++ + + D++ +EA+  D L+GF L H
Sbjct: 183 PFGQIFRPDNFVFGQ-SGAGNNWAKGHYTEGAELVDSVLDVVRKEAESCDCLQGFQLTH 10
>28905
          Length = 425

 Score = 58.2 bits (139), Expect = 7e-09,   Method: Composition-based stats.
 Identities = 33/135 (24%), Positives = 68/135 (50%), Gaps = 4/135 (2%)
 Frame = -1

Query: 254 IGLIASLIPTPRLHFLMTGYTPLTTDQSVASVRKTTVLDVMRRLLQPKNVMVST----GR 309
           + +  +++P PRLHF M G+ PLT+  S    R  TV ++ +++   KN+M +     GR
Sbjct: 395 VNVAVNMVPFPRLHFFMPGFAPLTSRGS-QQYRALTVPELTQQMFDAKNMMAACDPRHGR 219

Query: 310 DRQTNHCYIAILNIIQGEVDPTQVHKSLQRIRERKLANFIPWGPASIQVALSRKSPYLPS 369
                  Y+ +  + +G +   +V + +  ++ +  + F+ W P +++ A+       P 
Sbjct: 218 -------YLTVAAMFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIP---PR 69

Query: 370 AHRVSGLMMANHTSI 384
             ++SG  + N T+I
Sbjct: 68  GLKMSGTFIGNSTAI 24
>30297
          Length = 822

 Score = 29.3 bits (64), Expect = 3.3,   Method: Compositional matrix adjust.
 Identities = 12/36 (33%), Positives = 20/36 (55%)
 Frame = -2

Query: 334 HKSLQRIRERKLANFIPWGPASIQVALSRKSPYLPS 369
           H  L+R+  R     +PWGP+ ++  L+R  P  P+
Sbjct: 452 HPHLERLPGRPPHGTVPWGPSHLEEWLARWPPTRPT 345
>01993
          Length = 1915

 Score = 28.9 bits (63), Expect = 4.1,   Method: Compositional matrix adjust.
 Identities = 12/28 (42%), Positives = 17/28 (60%)
 Frame = -3

Query: 295 RRLLQPKNVMVSTGRDRQTNHCYIAILN 322
           R +L P  +M  T R++ TNH   +ILN
Sbjct: 341 RHILSPNTIMTKTHRNKVTNHVL*SILN 258
>33626
          Length = 391

 Score = 28.1 bits (61), Expect = 7.5,   Method: Composition-based stats.
 Identities = 17/55 (30%), Positives = 31/55 (56%)
 Frame = -3

Query: 230 QLVSTIMSASTTTLRYPGYMNNDLIGLIASLIPTPRLHFLMTGYTPLTTDQSVAS 284
           ++VS   +A+  +L +  ++NN  I +I  L+ T R    ++GY P  TD  ++S
Sbjct: 200 RVVSPFAAAARFSLLWFFFLNNLCILIIVFLVATDRNLNNISGYLPHLTDHFLSS 36
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|42415475|ref|NP_035162.1| prolyl 4-hydroxylase, beta
polypeptide [Mus musculus]
         (509 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

03582                                                                 432   e-140
35861                                                                 212   2e-88
06936                                                                 233   1e-61
28335                                                                 102   3e-22
36159                                                                  66   3e-11
18943                                                                  61   7e-11
21509                                                                  54   2e-09
18455                                                                  60   3e-09
14392                                                                  55   8e-08
04779                                                                  53   2e-07
04510                                                                  50   2e-06
30644                                                                  47   1e-05
15159                                                                  40   0.002
07257                                                                  37   0.021
38795                                                                  37   0.022
01000                                                                  35   0.088
>03582
          Length = 1967

 Score =  432 bits (1110), Expect(2) = e-140,   Method: Compositional matrix adjust.
 Identities = 209/345 (60%), Positives = 260/345 (75%)
 Frame = +3

Query: 132 KKRTGPAATTLSDTAAAESLVDSSEVTVIGFFKDVESDSAKQFLLAAEAIDDIPFGITSN 191
           +++TGP A  L D   A++  +  EV VIGFFKD +S+ A  F  AA  IDDIPFGITS+
Sbjct: 420 EEKTGPPAEDLKDKDEAKAFAEKDEVVVIGFFKDQKSEGAVAFTEAAAGIDDIPFGITSD 599

Query: 192 SGVFSKYQLDKDGVVLFKKFDEGRNNFEGEITKEKLLDFIKHNQLPLVIEFTEQTAPKIF 251
              F +Y++DKDG+VL KKFDEGRN+FEG+     ++  ++ NQLPLV+EFT+++A KIF
Sbjct: 600 ESAFKEYKMDKDGIVLLKKFDEGRNDFEGDFEPAAIIKHVRDNQLPLVVEFTQESAQKIF 779

Query: 252 GGEIKTHILLFLPKSVSDYDGKLSSFKRAAEGFKGKILFIFIDSDHTDNQRILEFFGLKK 311
           GGE+K HILLFL K   +    +  FK AA  FKGK+LFI++D+D  +N RI EFFGLK 
Sbjct: 780 GGEVKNHILLFLKKDGGE--DTIEKFKAAAGDFKGKVLFIYLDTDDAENGRITEFFGLKD 953

Query: 312 EECPAVRLITLEEEMTKYKPESDELTAEKITEFCHRFLEGKIKPHLMSQEVPEDWDKQPV 371
           EE PAVRLI L E+MTKYKPES +L  E I +F   FL+GK+  HLMS++VP DWD +PV
Sbjct: 954 EEIPAVRLIQLAEDMTKYKPESADLDTETIKKFVQDFLDGKLNAHLMSEDVPSDWDAKPV 1133

Query: 372 KVLVGANFEEVAFDEKKNVFVEFYAPWCGHCKQLAPIWDKLGETYKDHENIIIAKMDSTA 431
           KVLVG NF+EVA D+ K VFVEFYAPWCGHCKQLAPIWD+L + + D  +++IAKMDSTA
Sbjct: 1134KVLVGKNFKEVALDKTKGVFVEFYAPWCGHCKQLAPIWDELADKFTDKADVVIAKMDSTA 1313

Query: 432 NEVEAVKVHSFPTLKFFPASADRTVIDYNGERTLDGFKKFLESGG 476
           NE+E VKV SFPTLK+FP  +D  VIDYNGERTLD F KF+ESGG
Sbjct: 1314NEIEEVKVQSFPTLKYFPKDSDE-VIDYNGERTLDAFVKFVESGG 1445

 Score = 85.9 bits (211), Expect(2) = e-140,   Method: Compositional matrix adjust.
 Identities = 39/90 (43%), Positives = 56/90 (62%)
 Frame = +2

Query: 17  VGADALEEEDNVLVLKKSNFEEALAAHKYLLVEFYAPWCGHCXXXXXXXXXXXXXXXXXG 76
           V AD +++++ V VL   NF+  +  ++++LVEFYAPWCGHC                  
Sbjct: 86  VFADDVKQDEGVYVLTTKNFDSFVKENEFVLVEFYAPWCGHCKALAPEYAKAAQTLKDEN 265

Query: 77  SEIRLAKVDATEESDLAQQYGVRGYPTIKF 106
           S+++LAKVDAT E+ L +  GVRGYPT+KF
Sbjct: 266 SDVKLAKVDATIETSLGENMGVRGYPTLKF 355

 Score = 66.6 bits (161), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 37/80 (46%), Positives = 49/80 (61%), Gaps = 3/80 (3%)
 Frame = +2

Query: 371 VKVLVGANFEEVAFDEKKNVFVEFYAPWCGHCKQLAPIWDKLGETYKD-HENIIIAKMDS 429
           V VL   NF+     E + V VEFYAPWCGHCK LAP + K  +T KD + ++ +AK+D+
Sbjct: 119 VYVLTTKNFDSFV-KENEFVLVEFYAPWCGHCKALAPEYAKAAQTLKDENSDVKLAKVDA 295

Query: 430 TANEV--EAVKVHSFPTLKF 447
           T      E + V  +PTLKF
Sbjct: 296 TIETSLGENMGVRGYPTLKF 355

 Score = 52.0 bits (123), Expect = 6e-07,   Method: Compositional matrix adjust.
 Identities = 34/106 (32%), Positives = 55/106 (51%), Gaps = 1/106 (0%)
 Frame = +3

Query: 28   VLVLKKSNFEE-ALAAHKYLLVEFYAPWCGHCXXXXXXXXXXXXXXXXXGSEIRLAKVDA 86
            V VL   NF+E AL   K + VEFYAPWCGHC                  +++ +AK+D+
Sbjct: 1131 VKVLVGKNFKEVALDKTKGVFVEFYAPWCGHCKQLAPIWDELADKFTDK-ADVVIAKMDS 1307

Query: 87   TEESDLAQQYGVRGYPTIKFFKNGDTASPKEYTAGREADDIVNWLK 132
            T  ++  ++  V+ +PT+K+F   D+    +Y   R  D  V +++
Sbjct: 1308 T--ANEIEEVKVQSFPTLKYFPK-DSDEVIDYNGERTLDAFVKFVE 1436

 Score = 37.7 bits (86), Expect = 0.010,   Method: Compositional matrix adjust.
 Identities = 19/43 (44%), Positives = 26/43 (60%)
 Frame = +1

Query: 92  LAQQYGVRGYPTIKFFKNGDTASPKEYTAGREADDIVNWLKKR 134
           L ++YG         F+NG  +   EY+ GR+A DIV+WLKKR
Sbjct: 310 LGRKYGCTWISNP*IFRNGKDS---EYSGGRQAADIVSWLKKR 429
>35861
          Length = 850

 Score =  212 bits (540), Expect(3) = 2e-88,   Method: Compositional matrix adjust.
 Identities = 97/153 (63%), Positives = 124/153 (81%)
 Frame = +3

Query: 274 LSSFKRAAEGFKGKILFIFIDSDHTDNQRILEFFGLKKEECPAVRLITLEEEMTKYKPES 333
           L+ FK AA  FKGK+LFI++D+   +N RILEFFGL K++ PAVRLI L +EMTKYKPES
Sbjct: 285 LAKFKAAAGDFKGKVLFIYLDTAIEENGRILEFFGLVKDDTPAVRLIKLGDEMTKYKPES 464

Query: 334 DELTAEKITEFCHRFLEGKIKPHLMSQEVPEDWDKQPVKVLVGANFEEVAFDEKKNVFVE 393
            +L    I++F   F++GK+KPHL S+EVPEDWD +PVKVLV  NF+EVA D+ K+VFVE
Sbjct: 465 GDLDTATISKFVQDFMDGKLKPHLKSEEVPEDWDAKPVKVLVSKNFKEVALDKSKDVFVE 644

Query: 394 FYAPWCGHCKQLAPIWDKLGETYKDHENIIIAK 426
           FYAPWCGHCKQL PIWD+LGE ++D ++++IAK
Sbjct: 645 FYAPWCGHCKQLVPIWDELGEKFQDSDDVVIAK 743

 Score =  100 bits (250), Expect(3) = 2e-88,   Method: Compositional matrix adjust.
 Identities = 45/78 (57%), Positives = 60/78 (76%)
 Frame = +2

Query: 180 AIDDIPFGITSNSGVFSKYQLDKDGVVLFKKFDEGRNNFEGEITKEKLLDFIKHNQLPLV 239
            IDD+PFGITS+  +F +Y++DKDGVVL KKFDEGRN+F G+I  E +  FIK NQLPL+
Sbjct: 5   GIDDVPFGITSDKDIFKEYKMDKDGVVLXKKFDEGRNDFSGDIEAEAVAKFIKENQLPLI 184

Query: 240 IEFTEQTAPKIFGGEIKT 257
           +EFT+++A KI     +T
Sbjct: 185 VEFTQESAQKILAAT*RT 238

 Score = 52.8 bits (125), Expect(3) = 2e-88,   Method: Compositional matrix adjust.
 Identities = 25/39 (64%), Positives = 30/39 (76%)
 Frame = +1

Query: 424 IAKMDSTANEVEAVKVHSFPTLKFFPASADRTVIDYNGE 462
           + KMDSTANEVE V + SFPTL+ FP  +D  V+DYNGE
Sbjct: 736 LPKMDSTANEVEEVVIQSFPTLQIFP*GSDE-VVDYNGE 849

 Score = 42.4 bits (98), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 20/32 (62%), Positives = 22/32 (68%), Gaps = 1/32 (3%)
 Frame = +3

Query: 28  VLVLKKSNFEE-ALAAHKYLLVEFYAPWCGHC 58
           V VL   NF+E AL   K + VEFYAPWCGHC
Sbjct: 576 VKVLVSKNFKEVALDKSKDVFVEFYAPWCGHC 671
>06936
          Length = 2198

 Score =  233 bits (595), Expect = 1e-61,   Method: Compositional matrix adjust.
 Identities = 157/467 (33%), Positives = 232/467 (49%), Gaps = 21/467 (4%)
 Frame = +3

Query: 27  NVLVLKKSNFEEALAAHKYLLVEFYAPWCGHCXXXXXXXXXXXXXXXXXGSEIRLAKVDA 86
           +VL LKKS+F+  +  H  +LVEF+APWCGHC                    + LAKVD 
Sbjct: 147 DVLDLKKSDFQSTIEKHSLMLVEFFAPWCGHCKKLAPQYELAATALLKNDPPVPLAKVDC 326

Query: 87  TEESDLAQQYGVRGYPTIKFFKNGDTASPKEYTAGREADDIVNWLKKRTGPAATTLSDTA 146
           TEE+D+  +YGV GYPT+K F+ G+    K+Y   R+ D IV ++ K  GP +  L    
Sbjct: 327 TEETDVCSKYGVSGYPTLKVFRGGEVN--KDYDGPRDKDGIVKYMAKMAGPTSKELKSVE 500

Query: 147 AAESLVDSSEVTVIGFFKDVESDSAKQFLLAAEAIDDIPFGITSNSGVFSKYQLDKDGVV 206
             E  +      V+GFF    S  A      A++ D + FG T++S V  K +  KD +V
Sbjct: 501 EYEKFLSRDGSCVVGFFTGANSGMADTLKKVADSEDGLRFGYTTSSEVLEKAKY-KDEIV 677

Query: 207 LFK------KFDEGRNNFEGEITKEKLLDFIKHNQLPLVIEFTEQTAPKIFGGEIKTHIL 260
           LF+      KF++    F G+     +  F+K     L    T   A      + K  ++
Sbjct: 678 LFRPQKMANKFEDTAVKFTGDANSHNIKKFLKEESFGLCALRTMDNA-----ADFKKPVV 842

Query: 261 LFLPKSVSDYDGKLSSFKRAA----------EGFKGKILFIFIDSDHTDNQRILEFFGLK 310
           +         + K S++ R            EG   KI F   + +  DN+ +    GLK
Sbjct: 843 IAFFDVDYVKNAKGSNYWRNRVMKVGKKLRDEGL--KINFAVSNKNEFDNELVE--CGLK 1010

Query: 311 K----EECPAVRLITLEEEMTKYKPESDELTAEKITEFCHRFLEGKIKPHLMSQEVPEDW 366
           +     + PA+      ++  K+K +  E   +   +F    L+GK++ ++ S+ VP D 
Sbjct: 1011EAVDASDKPAI--CAYNDKNQKFKMDQ-EFAMDTFEQFVRDMLDGKLEAYMKSEPVP-DN 1178

Query: 367 DKQPVKVLVGANFEEVAFDEKKNVFVEFYAPWCGHCKQLAPIWDKLGETYKDHENIIIAK 426
            +  VKV VG NFEE+  D +K+V +EFYAPWCGHCK LAP +D+L E  K+   I+IAK
Sbjct: 1179SENAVKVAVGRNFEELVNDPEKDVLIEFYAPWCGHCKTLAPKYDELAEKLKNEPEIVIAK 1358

Query: 427 MDSTANEV-EAVKVHSFPTLKFFPASADRTVIDYNGERTLDGFKKFL 472
           MD+TAN+V     V  FPTL F P  +  +   Y G R ++ F K+L
Sbjct: 1359MDATANDVPPPYDVRGFPTLYFAPKGSKSSPKKYEGGREVNDFVKYL 1499

 Score = 80.9 bits (198), Expect = 1e-15,   Method: Compositional matrix adjust.
 Identities = 46/110 (41%), Positives = 60/110 (54%), Gaps = 1/110 (0%)
 Frame = +3

Query: 25   EDNVLVLKKSNFEEALA-AHKYLLVEFYAPWCGHCXXXXXXXXXXXXXXXXXGSEIRLAK 83
            E+ V V    NFEE +    K +L+EFYAPWCGHC                   EI +AK
Sbjct: 1182 ENAVKVAVGRNFEELVNDPEKDVLIEFYAPWCGHCKTLAPKYDELAEKLKNE-PEIVIAK 1358

Query: 84   VDATEESDLAQQYGVRGYPTIKFFKNGDTASPKEYTAGREADDIVNWLKK 133
            +DAT  +D+   Y VRG+PT+ F   G  +SPK+Y  GRE +D V +L K
Sbjct: 1359 MDATA-NDVPPPYDVRGFPTLYFAPKGSKSSPKKYEGGREVNDFVKYLAK 1505
>28335
          Length = 601

 Score =  102 bits (254), Expect = 3e-22,   Method: Compositional matrix adjust.
 Identities = 48/121 (39%), Positives = 76/121 (62%), Gaps = 1/121 (0%)
 Frame = -2

Query: 353 IKPHLMSQEVPEDWDKQPVKVLVGANFEEVAFDEKKNVFVEFYAPWCGHCKQLAPIWDKL 412
           I+P+L SQ +P++ ++ PVK  VG  F+++  + KK+V +EFYAPWCGHC+QL P +++L
Sbjct: 597 IQPYLKSQPIPQN-EEGPVKTAVGRTFDKIVNNPKKDVLIEFYAPWCGHCQQLEPKYNEL 421

Query: 413 GETYKDHENIIIAKMDSTANEVE-AVKVHSFPTLKFFPASADRTVIDYNGERTLDGFKKF 471
               KD  +I+ AK+D+TAN+     +V  FP + F P         Y G+R +D   K+
Sbjct: 420 ATLLKDEPDIVXAKIDATANDTPTPYEVKGFPAIYFSPKRFKEFPKKYEGDREVDAMLKY 241

Query: 472 L 472
           +
Sbjct: 240 I 238

 Score = 56.2 bits (134), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 31/90 (34%), Positives = 44/90 (48%)
 Frame = -2

Query: 44  KYLLVEFYAPWCGHCXXXXXXXXXXXXXXXXXGSEIRLAKVDATEESDLAQQYGVRGYPT 103
           K +L+EFYAPWCGHC                   +I  AK+DAT  +D    Y V+G+P 
Sbjct: 495 KDVLIEFYAPWCGHCQQLEPKYNELATLLKDE-PDIVXAKIDAT-ANDTPTPYEVKGFPA 322

Query: 104 IKFFKNGDTASPKEYTAGREADDIVNWLKK 133
           I F        PK+Y   RE D ++ ++ +
Sbjct: 321 IYFSPKRFKEFPKKYEGDREVDAMLKYIAR 232
>36159
          Length = 369

 Score = 65.9 bits (159), Expect = 3e-11,   Method: Composition-based stats.
 Identities = 24/34 (70%), Positives = 31/34 (91%)
 Frame = -1

Query: 396 APWCGHCKQLAPIWDKLGETYKDHENIIIAKMDS 429
           APWCGHCKQL PIWD+LGE ++D ++++IAKMDS
Sbjct: 102 APWCGHCKQLVPIWDELGEKFQDSDDVVIAKMDS 1
>18943
          Length = 1035

 Score = 60.8 bits (146), Expect(2) = 7e-11,   Method: Compositional matrix adjust.
 Identities = 51/176 (28%), Positives = 86/176 (48%), Gaps = 3/176 (1%)
 Frame = +2

Query: 78  EIRLAKVDATEESDLAQQYGVRGYPTIKFFKNGDTASPKEYTAGREADDIVNWLKKRTGP 137
           ++  AKVD  +E  +A QY +  YPT+K F+NG     KE+   R AD +  ++++    
Sbjct: 278 KVLFAKVDCDKEVTIASQYRISKYPTLKLFRNGQMVK-KEFRGQRSADALAAFIREELKD 454

Query: 138 AATTLSDTAAAESLVDSSEVTVIGFFKDVESDSAKQFLLAAEAIDDIPFGITSNSGVFSK 197
           +    +     E L D+ +  VIG+F+  ESD+ K FL  A ++ D     T+   V + 
Sbjct: 455 SVVDHNTLDKLEEL-DTKKRQVIGYFEAKESDNYKTFLRVASSLRDNCIFNTAVGPVSAS 631

Query: 198 YQLDKDGVVLFKKFDEGRNN--FEGEITK-EKLLDFIKHNQLPLVIEFTEQTAPKI 250
            +   D V  F+     R +  F G +   ++LL +     +PLV E T + A ++
Sbjct: 632 ERTGGDYVA-FRPPHTQRQDVVFMGPLNNFDQLLSWALDKCVPLVREITFENAEEL 796

 Score = 24.3 bits (51), Expect(2) = 7e-11,   Method: Compositional matrix adjust.
 Identities = 8/27 (29%), Positives = 13/27 (48%)
 Frame = +3

Query: 29  LVLKKSNFEEALAAHKYLLVEFYAPWC 55
           + L   N    ++ +  + V FYA WC
Sbjct: 123 VALNNDNINTIISRNDVVFVNFYADWC 203
>21509
          Length = 754

 Score = 53.5 bits (127), Expect(2) = 2e-09,   Method: Compositional matrix adjust.
 Identities = 28/62 (45%), Positives = 41/62 (66%), Gaps = 1/62 (1%)
 Frame = -3

Query: 81  LAKVDATEESDLAQQYGVRGYPTIKFFKNGDTASPKEYTAGREADDIVNWLKKR-TGPAA 139
           +A VDAT + +L  +Y V+GYPT+K+FK+G  A   EY+ GR +D  V+++KK   GP  
Sbjct: 569 VAAVDATLDPELGNKYDVKGYPTLKYFKDGKLAF--EYSGGRSSDAFVSFMKKAGAGPTL 396

Query: 140 TT 141
            T
Sbjct: 395 PT 390

 Score = 26.2 bits (56), Expect(2) = 2e-09,   Method: Compositional matrix adjust.
 Identities = 8/11 (72%), Positives = 8/11 (72%)
 Frame = -2

Query: 48  VEFYAPWCGHC 58
              YAPWCGHC
Sbjct: 663 CHVYAPWCGHC 631

 Score = 42.0 bits (97), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 16/28 (57%), Positives = 20/28 (71%)
 Frame = -1

Query: 31  LKKSNFEEALAAHKYLLVEFYAPWCGHC 58
           L  + FE  +AA++  LV FYAPWCGHC
Sbjct: 346 LTDATFESFIAANRRTLVMFYAPWCGHC 263

 Score = 40.0 bits (92), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 17/39 (43%), Positives = 23/39 (58%)
 Frame = -1

Query: 371 VKVLVGANFEEVAFDEKKNVFVEFYAPWCGHCKQLAPIW 409
           V  L  A FE      ++ + V FYAPWCGHCK++ P +
Sbjct: 355 VNHLTDATFESFIAANRRTL-VMFYAPWCGHCKKMKPAY 242

 Score = 28.5 bits (62), Expect = 6.8,   Method: Compositional matrix adjust.
 Identities = 9/13 (69%), Positives = 10/13 (76%)
 Frame = -2

Query: 392 VEFYAPWCGHCKQ 404
              YAPWCGHCK+
Sbjct: 663 CHVYAPWCGHCKK 625
>18455
          Length = 499

 Score = 59.7 bits (143), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 29/87 (33%), Positives = 48/87 (55%), Gaps = 2/87 (2%)
 Frame = +2

Query: 389 NVFVEFYAPWCGHCKQLAPIWDKLGETYKDHENIIIAKMDSTANE--VEAVKVHSFPTLK 446
           N FV+F+APWC HC++LAPIW++L +      +  I+K+D T      +  +V  +PTL 
Sbjct: 194 NHFVKFFAPWCSHCQRLAPIWEELAKALIKEPSATISKIDCTQYRSICQDFEVKGYPTLL 373

Query: 447 FFPASADRTVIDYNGERTLDGFKKFLE 473
           +      + +  Y G R +   K ++E
Sbjct: 374 WI--EDGKKIEKYAGARDMVTLKTYVE 448

 Score = 47.0 bits (110), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 26/109 (23%), Positives = 53/109 (48%)
 Frame = +2

Query: 28  VLVLKKSNFEEALAAHKYLLVEFYAPWCGHCXXXXXXXXXXXXXXXXXGSEIRLAKVDAT 87
           V+ L +  F + +++  +  V+F+APWC HC                  S   ++K+D T
Sbjct: 146 VVDLTEDTFAKHVSSGNHF-VKFFAPWCSHCQRLAPIWEELAKALIKEPSAT-ISKIDCT 319

Query: 88  EESDLAQQYGVRGYPTIKFFKNGDTASPKEYTAGREADDIVNWLKKRTG 136
           +   + Q + V+GYPT+ + ++G     ++Y   R+   +  +++K  G
Sbjct: 320 QYRSICQDFEVKGYPTLLWIEDGKKI--EKYAGARDMVTLKTYVEKMIG 460
>14392
          Length = 468

 Score = 54.7 bits (130), Expect = 8e-08,   Method: Compositional matrix adjust.
 Identities = 29/69 (42%), Positives = 42/69 (60%), Gaps = 1/69 (1%)
 Frame = +2

Query: 405 LAPIWDKLGETYKDHENIIIAKMDSTANEVEA-VKVHSFPTLKFFPASADRTVIDYNGER 463
           L PI+++L E  +D E++ I KMD+TAN+V     V  FPTL + P  +    + YNG R
Sbjct: 2   LTPIYEELAEKLQD-EDVAIVKMDATANDVPPEFNVRGFPTLFWLPKDSKNKPVSYNGGR 178

Query: 464 TLDGFKKFL 472
            LD F K++
Sbjct: 179 ELDDFIKYI 205

 Score = 42.0 bits (97), Expect = 6e-04,   Method: Compositional matrix adjust.
 Identities = 18/56 (32%), Positives = 32/56 (57%)
 Frame = +2

Query: 78  EIRLAKVDATEESDLAQQYGVRGYPTIKFFKNGDTASPKEYTAGREADDIVNWLKK 133
           ++ + K+DAT  +D+  ++ VRG+PT+ +        P  Y  GRE DD + ++ K
Sbjct: 47  DVAIVKMDATA-NDVPPEFNVRGFPTLFWLPKDSKNKPVSYNGGRELDDFIKYIAK 211
>04779
          Length = 910

 Score = 53.1 bits (126), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 26/56 (46%), Positives = 35/56 (62%), Gaps = 2/56 (3%)
 Frame = +1

Query: 77  SEIRLAKVDATEESDLAQQYGVRGYPTIKFF-KNGDTAS-PKEYTAGREADDIVNW 130
            +++   +DAT   + A +Y VRGYPTIKFF  N + AS  +EY  GR A DI+ W
Sbjct: 10  GKVKFGALDATAHQNKAAEYNVRGYPTIKFFPANSNRASDAQEYNGGRTASDIIAW 177

 Score = 37.4 bits (85), Expect = 0.016,   Method: Compositional matrix adjust.
 Identities = 18/42 (42%), Positives = 30/42 (71%), Gaps = 4/42 (9%)
 Frame = +1

Query: 427 MDSTANEVEAVK--VHSFPTLKFFPASADRT--VIDYNGERT 464
           +D+TA++ +A +  V  +PT+KFFPA+++R     +YNG RT
Sbjct: 31  LDATAHQNKAAEYNVRGYPTIKFFPANSNRASDAQEYNGGRT 156
>04510
          Length = 685

 Score = 50.1 bits (118), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 19/35 (54%), Positives = 26/35 (74%)
 Frame = +2

Query: 24  EEDNVLVLKKSNFEEALAAHKYLLVEFYAPWCGHC 58
           +  +VL LKKS+F+  +  H  +LVEF+APWCGHC
Sbjct: 344 QASDVLDLKKSDFQSTIEKHSLMLVEFFAPWCGHC 448

 Score = 42.0 bits (97), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 14/21 (66%), Positives = 19/21 (90%)
 Frame = +2

Query: 390 VFVEFYAPWCGHCKQLAPIWD 410
           + VEF+APWCGHCK+LAP ++
Sbjct: 410 MLVEFFAPWCGHCKKLAPQYE 472
>30644
          Length = 845

 Score = 47.4 bits (111), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 21/40 (52%), Positives = 26/40 (65%)
 Frame = -1

Query: 19  ADALEEEDNVLVLKKSNFEEALAAHKYLLVEFYAPWCGHC 58
           A+  EE   V  L+ SNF++ L  H  +LV FYAPWCGHC
Sbjct: 131 AEWSEEPSEVAHLEDSNFDDFLKQHPSVLVMFYAPWCGHC 12

 Score = 40.8 bits (94), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 19/44 (43%), Positives = 28/44 (63%), Gaps = 4/44 (9%)
 Frame = -1

Query: 365 DWDKQPVKVLVGANFEEVAFD----EKKNVFVEFYAPWCGHCKQ 404
           +W ++P +V   A+ E+  FD    +  +V V FYAPWCGHCK+
Sbjct: 128 EWSEEPSEV---AHLEDSNFDDFLKQHPSVLVMFYAPWCGHCKK 6

 Score = 38.9 bits (89), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 16/47 (34%), Positives = 24/47 (51%), Gaps = 5/47 (10%)
 Frame = -3

Query: 366 WDKQP-----VKVLVGANFEEVAFDEKKNVFVEFYAPWCGHCKQLAP 407
           WD+ P     V +       ++   +K    V FYAPWCG+CK++ P
Sbjct: 504 WDEDPTATDVVHIDTDDGLTKLLKKDKSAALVMFYAPWCGYCKRMKP 364

 Score = 32.7 bits (73), Expect = 0.39,   Method: Compositional matrix adjust.
 Identities = 10/12 (83%), Positives = 11/12 (91%)
 Frame = -3

Query: 47  LVEFYAPWCGHC 58
           LV FYAPWCG+C
Sbjct: 414 LVMFYAPWCGYC 379
>15159
          Length = 1945

 Score = 40.0 bits (92), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 20/74 (27%), Positives = 35/74 (47%)
 Frame = +3

Query: 35  NFEEALAAHKYLLVEFYAPWCGHCXXXXXXXXXXXXXXXXXGSEIRLAKVDATEESDLAQ 94
           +FE+A+   + ++V+F+A WCG C                  + +++  VD  E  DLA 
Sbjct: 105 DFEKAIQGGQLVVVDFHATWCGPCKVIAPKLAKWSEEDRFKET-VKIISVDVDELEDLAG 281

Query: 95  QYGVRGYPTIKFFK 108
           + G+   PT  F +
Sbjct: 282 EQGISAMPTFFFLE 323

 Score = 36.6 bits (83), Expect = 0.026,   Method: Compositional matrix adjust.
 Identities = 24/80 (30%), Positives = 38/80 (47%), Gaps = 2/80 (2%)
 Frame = +3

Query: 371 VKVLVGANFEEVAFDEKKNVFVEFYAPWCGHCKQLAPIWDKLGE--TYKDHENIIIAKMD 428
           +K+    +FE+ A    + V V+F+A WCG CK +AP   K  E   +K+   II   +D
Sbjct: 84  IKISSADDFEK-AIQGGQLVVVDFHATWCGPCKVIAPKLAKWSEEDRFKETVKIISVDVD 260

Query: 429 STANEVEAVKVHSFPTLKFF 448
              +      + + PT  F 
Sbjct: 261 ELEDLAGEQGISAMPTFFFL 320
>07257
          Length = 1477

 Score = 37.0 bits (84), Expect = 0.021,   Method: Compositional matrix adjust.
 Identities = 23/84 (27%), Positives = 37/84 (44%), Gaps = 1/84 (1%)
 Frame = -3

Query: 390  VFVEFYAPWCGHCKQLAPIWDKLGETYKDHENIIIAKMDSTANEVEAVKVHSFPTLKFFP 449
            V V FYAPWC  C   AP ++ L   +   E + +  +  +        V + P +  F 
Sbjct: 1289 VLVMFYAPWCHFCANTAPHYNALARAFPQLEVLAVDTVHFSNLNARFGTV-AVPNIMLFH 1113

Query: 450  ASADRTVIDYN-GERTLDGFKKFL 472
             S  R+ + +N  ER    F +F+
Sbjct: 1112 QS--RSAVRFNHTERDFHTFLQFI 1047

 Score = 36.6 bits (83), Expect = 0.026,   Method: Compositional matrix adjust.
 Identities = 22/91 (24%), Positives = 35/91 (38%)
 Frame = -3

Query: 46   LLVEFYAPWCGHCXXXXXXXXXXXXXXXXXGSEIRLAKVDATEESDLAQQYGVRGYPTIK 105
            +LV FYAPWC  C                   ++ +  VD    S+L  ++G    P I 
Sbjct: 1289 VLVMFYAPWCHFCANTAPHYNALARAF----PQLEVLAVDTVHFSNLNARFGTVAVPNIM 1122

Query: 106  FFKNGDTASPKEYTAGREADDIVNWLKKRTG 136
             F    +A    +T  R+    + ++   TG
Sbjct: 1121 LFHQSRSAVRFNHTE-RDFHTFLQFIANTTG 1032
>38795
          Length = 792

 Score = 36.6 bits (83), Expect = 0.022,   Method: Compositional matrix adjust.
 Identities = 29/101 (28%), Positives = 47/101 (46%)
 Frame = +1

Query: 300 NQRILEFFGLKKEECPAVRLITLEEEMTKYKPESDELTAEKITEFCHRFLEGKIKPHLMS 359
           NQ+ L+++G   +     RL  LE +  +YK E D+++  K   +  RF  G  K    +
Sbjct: 343 NQKKLQYYGGNYDSYVQTRLELLENQAKRYKWEQDQISHMK--NYIARFGHGSAKLARQA 516

Query: 360 QEVPEDWDKQPVKVLVGANFEEVAFDEKKNVFVEFYAPWCG 400
           Q      +K   K++ G   E+V  D+     + FY P CG
Sbjct: 517 QSK----EKTLKKMVDGGLTEKVTSDKT----LSFYFPSCG 615
>01000
          Length = 1541

 Score = 34.7 bits (78), Expect = 0.088,   Method: Compositional matrix adjust.
 Identities = 15/44 (34%), Positives = 25/44 (56%)
 Frame = -1

Query: 84   VDATEESDLAQQYGVRGYPTIKFFKNGDTASPKEYTAGREADDI 127
            VD T++S+      +RGYPT+  F+NG     +++   R  DD+
Sbjct: 1541 VDCTKQSETCNAQSIRGYPTLAVFQNG--KRQEDFKGTRSLDDL 1416
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6753322|ref|NP_033967.1| chaperonin containing Tcp1,
subunit 4 (delta) [Mus musculus]
         (539 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

12796                                                                 491   e-139
06409                                                                 479   e-135
01159                                                                 320   7e-88
33770                                                                 234   4e-62
05356                                                                 132   1e-60
29631                                                                 134   2e-43
09900                                                                 157   8e-39
29864                                                                 147   1e-35
02673                                                                  79   3e-15
17249                                                                  65   7e-11
30661                                                                  64   1e-10
29327                                                                  64   2e-10
34332                                                                  37   0.024
10291                                                                  32   0.57 
16801                                                                  30   3.5  
>12796
          Length = 1316

 Score =  491 bits (1264), Expect = e-139,   Method: Compositional matrix adjust.
 Identities = 237/339 (69%), Positives = 292/339 (86%), Gaps = 1/339 (0%)
 Frame = -3

Query: 201  TSVDLRDIKIVKKLGGTIDDCELVEGLVLTQKVANSGI-TRVEKAKIGLIQFCLSAPKTD 259
            TSVDL++IK+++ LGGT++D ELV GLV T + A +    R+EKAKIGLIQFC+SAPKTD
Sbjct: 1314 TSVDLKNIKVIRSLGGTVEDTELVNGLVFTSRSAGTNAPKRIEKAKIGLIQFCISAPKTD 1135

Query: 260  MDNQIVVSDYAQMDRVLREERAYILNLVKQIKKTGCNVLLIQKSILRDALSDLALHFLNK 319
            MD+ ++VSDYA MDRVL+EER+YILN+VKQIKK GCNVLL+QKSILRDA+SDLA HFL+K
Sbjct: 1134 MDHNVIVSDYAAMDRVLKEERSYILNIVKQIKKAGCNVLLVQKSILRDAVSDLAQHFLDK 955

Query: 320  MKIMVVKDVEREDIEFICKTIGTKPVAHIDQFTADMLGSAELAEEVSLNGSGKLFKITGC 379
            +K +VVKDVEREDIEF+CKT+  +P+A +D FTA+ + SA+L EEV+ +G+ K  KITG 
Sbjct: 954  IKCLVVKDVEREDIEFVCKTLHCRPIASLDHFTAENMSSADLVEEVA-SGTNKFVKITGI 778

Query: 380  TSPGKTVTIVVRGSNKLVIEEAERSIHDALCVIRCLVKKRALIAGGGAPEIELALRLTEY 439
             + G+TV+I+ RGSNKLV+EEA RS+HDALCV+RCLV+ RA I GGGAPEIE+AL+L   
Sbjct: 777  QNQGRTVSIICRGSNKLVLEEAARSLHDALCVVRCLVRNRAQIVGGGAPEIEMALQLAAA 598

Query: 440  SRTLSGMESYCVRAFADAMEVIPSTLAENAGLNPISTVTELRNRHAQGEKTTGINVRKGG 499
            ++T+ G+++YC RAFADA+EVIPSTLAENAGLNPI+TVTELRNRHAQGEK  GINVRKG 
Sbjct: 597  AQTVDGVDAYCYRAFADALEVIPSTLAENAGLNPIATVTELRNRHAQGEKNAGINVRKGA 418

Query: 500  ISNILEEMVVQPLLVSVSALTLATETVRSILKIDDVVNT 538
            I++I  E VVQPLLVS SA+TLATETVRSILKIDD+VNT
Sbjct: 417  ITDIFAENVVQPLLVSTSAITLATETVRSILKIDDIVNT 301
>06409
          Length = 1533

 Score =  479 bits (1233), Expect = e-135,   Method: Compositional matrix adjust.
 Identities = 225/301 (74%), Positives = 266/301 (88%)
 Frame = -3

Query: 237  GITRVEKAKIGLIQFCLSAPKTDMDNQIVVSDYAQMDRVLREERAYILNLVKQIKKTGCN 296
            G ++VEKAKIG IQFC+S PKTDM+NQ++VSDY QMDRVLREER YIL++VK+IKK GCN
Sbjct: 1504 GPSKVEKAKIGFIQFCISPPKTDMENQVIVSDYTQMDRVLREERNYILDIVKKIKKAGCN 1325

Query: 297  VLLIQKSILRDALSDLALHFLNKMKIMVVKDVEREDIEFICKTIGTKPVAHIDQFTADML 356
            VLLIQKSILRDA+SDLALHFL KMKIMVVKD+ERED+EF+CKT+G +PVA +D F  + L
Sbjct: 1324 VLLIQKSILRDAVSDLALHFLAKMKIMVVKDIEREDVEFVCKTLGCRPVASLDHFLPENL 1145

Query: 357  GSAELAEEVSLNGSGKLFKITGCTSPGKTVTIVVRGSNKLVIEEAERSIHDALCVIRCLV 416
            GSA+L EEV   GS K+ K TG  +PG+TVT+++RGSNKLV+EEA+RS+HDALCVIRCLV
Sbjct: 1144 GSADLIEEVQ-TGSSKIVKATGIANPGQTVTVLIRGSNKLVLEEADRSLHDALCVIRCLV 968

Query: 417  KKRALIAGGGAPEIELALRLTEYSRTLSGMESYCVRAFADAMEVIPSTLAENAGLNPIST 476
            KK+ALIAGGGAPE E+++RL  Y+ TL+GME YC RAFA+A+EVIP TLAENAGLNPIST
Sbjct: 967  KKKALIAGGGAPETEMSMRLAAYANTLAGMEQYCFRAFAEALEVIPFTLAENAGLNPIST 788

Query: 477  VTELRNRHAQGEKTTGINVRKGGISNILEEMVVQPLLVSVSALTLATETVRSILKIDDVV 536
            VT LR RHAQGE+T GINVRKG I+NILEE V+QPLLVS SA+TLA+ETVRSILKIDD+V
Sbjct: 787  VTXLRTRHAQGERTAGINVRKGAITNILEENVLQPLLVSTSAITLASETVRSILKIDDIV 608

Query: 537  N 537
            N
Sbjct: 607  N 605
>01159
          Length = 2613

 Score =  320 bits (821), Expect = 7e-88,   Method: Compositional matrix adjust.
 Identities = 200/529 (37%), Positives = 320/529 (60%), Gaps = 18/529 (3%)
 Frame = +3

Query: 25  QDRDKPAQI-----RFSNISAAKAVADAIRTSLGPKGMDKMIQDGKGDVTITNDGATILK 79
           +D+DK +++       S+I AAK+VA  ++TSLGPKG+DKM+  G GDVT+TNDGATIL 
Sbjct: 150 RDQDKKSRLTGIEAHKSHILAAKSVASILKTSLGPKGLDKMMVSGDGDVTVTNDGATILD 329

Query: 80  QMQVLHPAARMLVELSKAQDIEAGDGTTSVVIIAGSLLDSCTKLLQKGIHPTIISESFQK 139
            M V H  A+++V+LSK+QD E GDGTT VV++AG+LL+   KLL +GIHP  I++ ++ 
Sbjct: 330 MMDVDHQIAKLMVQLSKSQDDEIGDGTTGVVVLAGALLEQAEKLLDRGIHPIRIADGYEI 509

Query: 140 ALEKGLEILTDMS--RPVQLSDRETLLNSATTSLNSKVVSQYSSLLSPMSVNAVMKVIDP 197
           A +  +E L  +S    V L + E L+  A T+L SK+V++    ++ ++V+A+M V D 
Sbjct: 510 AAKCAVETLDKISDNYEVDLKNAEPLIKLAMTTLGSKIVNRCHRQMAKIAVDAIMSVAD- 686

Query: 198 ATATSVDLRDIKIVKKLGGTIDDCELVEGLVLTQKVANSGITRVEK-AKIGLIQFCLSAP 256
                VD   IK+  K+GG ++D  LV+G+V+ + +++  + +V K AKI ++      P
Sbjct: 687 LKRKDVDFELIKVEGKVGGKLEDTMLVKGVVVDKDMSHPQMPKVVKDAKIAILTCPFEPP 866

Query: 257 KTDMDNQI---VVSDYAQMDRVLREERAYILN----LVKQIKKTGCNVLLIQKSILRDAL 309
           K    +++    V DY ++       R Y LN    +V+ +K  G N+++ Q        
Sbjct: 867 KPKTKHKLDITSVEDYKKL-------REYELNKFESMVQSVKDKGANLVICQW-----GF 1010

Query: 310 SDLALHFLNKMKIMVVKDVEREDIEFICKTIGTKPVAHIDQFTADMLGSAELAEEVSLNG 369
            D A H L + ++  V+ V   +IE I    G + V   ++ T + LG A +  E++   
Sbjct: 1011DDEANHLLLQRELPAVRWVGGPEIELIAIATGGRIVPRFEELTTEKLGKAGIVRELTFGT 1190

Query: 370 S-GKLFKITGCTSPGKTVTIVVRGSNKLVIEEAERSIHDALCVIRCLVKKRALIAGGGAP 428
           +  ++  I  C +  + VTI +RG NK+++EEA+RS+HDALCVIR LV+   ++ GGGAP
Sbjct: 1191TKDRMLVIEECLNT-RAVTIFIRGGNKMIVEEAKRSLHDALCVIRNLVRDNRVVYGGGAP 1367

Query: 429 EIELALRLTEYSRTLSGMESYCVRAFADAMEVIPSTLAENAGLNPISTVTELRNRHAQGE 488
           EI  ++ + E +  +S +E Y VR+F++A+E +P  LAEN+GL PI T+ E+++R  + E
Sbjct: 1368EIAASVAVAEAADKISTLEQYAVRSFSEALEAVPLALAENSGLAPIQTLAEVKSRQVK-E 1544

Query: 489 KTT--GINVRKGGISNILEEMVVQPLLVSVSALTLATETVRSILKIDDV 535
           K    GI+    G +++ E+ V++ L      + LAT+ VR ILKIDD+
Sbjct: 1545KNPRLGIDCLLKGTNDMKEQNVIETLTAKKQQILLATQLVRMILKIDDI 1691
>33770
          Length = 484

 Score =  234 bits (598), Expect = 4e-62,   Method: Compositional matrix adjust.
 Identities = 124/161 (77%), Positives = 148/161 (91%)
 Frame = +1

Query: 59  KMIQDGKGDVTITNDGATILKQMQVLHPAARMLVELSKAQDIEAGDGTTSVVIIAGSLLD 118
           KMIQ   GDVTITNDGATILKQMQVLHPAA+MLVELSKAQDIE GDGTT+VV++AGSLLD
Sbjct: 1   KMIQAANGDVTITNDGATILKQMQVLHPAAKMLVELSKAQDIEXGDGTTTVVVLAGSLLD 180

Query: 119 SCTKLLQKGIHPTIISESFQKALEKGLEILTDMSRPVQLSDRETLLNSATTSLNSKVVSQ 178
           +  KLL KGIHPT+ISE+FQKA  K +E+L  M +P++LSDRE+LL+SA+TSLNSKVVSQ
Sbjct: 181 ASAKLLAKGIHPTMISEAFQKAASKCVELLDGMVKPLELSDRESLLSSASTSLNSKVVSQ 360

Query: 179 YSSLLSPMSVNAVMKVIDPATATSVDLRDIKIVKKLGGTID 219
           YSS+L+P++V+AV+KVIDPATAT+VDL+DIKI+KKLGGTID
Sbjct: 361 YSSMLAPIAVDAVLKVIDPATATNVDLKDIKIIKKLGGTID 483
>05356
          Length = 2339

 Score =  132 bits (333), Expect(2) = 1e-60,   Method: Compositional matrix adjust.
 Identities = 84/269 (31%), Positives = 153/269 (56%), Gaps = 4/269 (1%)
 Frame = +2

Query: 35  FSNISAAKAVADAIRTSLGPKGMDKMIQDGKGDVTITNDGATILKQMQVLHPAARMLVEL 94
           + NI A K +A   R++ GP G +KM+ +    + +TND ATIL++++V HPAA+MLV  
Sbjct: 278 YRNIEACKELAKTTRSAYGPHGQNKMVINHLEKLFVTNDAATILRELEVQHPAAKMLVLA 457

Query: 95  SKAQDIEAGDGTTSVVIIAGSLLDSCTKLLQKGIHPTIISESFQKALEKGLEILTDM--S 152
           +  Q+ E GDGT  V++ AG+LL++  +LL+ G+  T + E ++ AL+K  EIL  +   
Sbjct: 458 AHQQEQECGDGTNFVLVFAGALLENAEQLLRMGLSVTEVIEGYELALKKAHEILPKLVIG 637

Query: 153 RPVQLSDRETLLNSATTSLNSKVVSQYSS--LLSPMSVNAVMKVIDPATATSVDLRDIKI 210
               L ++E +  +  TS+ SK   QY +   L+ +  +A + V+    + SVD  ++++
Sbjct: 638 HVKNLRNKEEVKTAIRTSVMSK---QYGNEDFLADLITDACVSVLPAKISFSVD--NVRV 802

Query: 211 VKKLGGTIDDCELVEGLVLTQKVANSGITRVEKAKIGLIQFCLSAPKTDMDNQIVVSDYA 270
            K LG  +     ++G+V  ++V    IT+VEKAK+ +    L + +T+    +++ +  
Sbjct: 803 CKILGCGLLQSSTIQGMVFKRQVEGE-ITKVEKAKVAVFTCPLDSMQTETKGTVLIKNAE 979

Query: 271 QMDRVLREERAYILNLVKQIKKTGCNVLL 299
           ++    + E   +   +K IK+ G NV++
Sbjct: 980 ELMSFSKGEEDMMEEQIKGIKEAGVNVIV 1066

 Score =  119 bits (298), Expect(2) = 1e-60,   Method: Compositional matrix adjust.
 Identities = 66/233 (28%), Positives = 125/233 (53%), Gaps = 5/233 (2%)
 Frame = +1

Query: 309  LSDLALHFLNKMKIMVVKDVEREDIEFICKTIGTKPVAHIDQFTADMLGSAELAEEVSLN 368
            + DLA H+ NK K+MV++ + + D+  +CK+I    +  +     +  G  +L   V ++
Sbjct: 1078 VGDLAQHYCNKYKVMVIRLLSKWDLRRLCKSICATALPKVTTPRNEECGYCDL---VYVD 1248

Query: 369  GSGK----LFKITGCTSPGKTVTIVVRGSNKLVIEEAERSIHDALCVIRCLVKKRALIAG 424
              G+    +F+     SP    T+++RGS   ++++ ER++ D +   + L K   L+ G
Sbjct: 1249 EIGETPVVIFQQNKDESP--ITTVIIRGSTDNIMDDIERALDDGVNTFKALTKDDRLVPG 1422

Query: 425  GGAPEIELALRLTEYSRTLSGMESYCVRAFADAMEVIPSTLAENAGLNPISTVTELRNRH 484
             GA EIELA ++T Y  +L G+E Y V+ FA+++EVIP  LAEN G+     +++L   H
Sbjct: 1423 AGATEIELAKQITTYGESLPGLEQYAVKKFAESLEVIPRALAENTGMKATDILSKLYAAH 1602

Query: 485  AQGEKTTGINV-RKGGISNILEEMVVQPLLVSVSALTLATETVRSILKIDDVV 536
             +G++  G+++   G + +  +  +    L     L  A     ++L++D ++
Sbjct: 1603 QEGQQNAGVDIDDSGSVLDAKQANLTDLYLNRYWGLKFAAAAACTVLRVDQII 1761
>29631
          Length = 1257

 Score =  134 bits (337), Expect(2) = 2e-43,   Method: Compositional matrix adjust.
 Identities = 63/143 (44%), Positives = 98/143 (68%), Gaps = 1/143 (0%)
 Frame = +3

Query: 27  RDKPAQIRFSNISAAKAVADAIRTSLGPKGMDKMIQDGKGDVTITNDGATILKQMQVLHP 86
           R+   +++  NI+A K +AD IRT LGPK M KM+ D  G + +TNDG  IL+++ V HP
Sbjct: 30  RESGRKVQLGNIAAGKTIADVIRTCLGPKSMLKMLMDPMGGIVMTNDGNAILREINVQHP 209

Query: 87  AARMLVELSKAQDIEAGDGTTSVVIIAGSLLDSCTKLLQKGIHPTIISESFQKALEKGLE 146
           AA+ ++E+++ QD E GDGT SV+I+AG +L    + L++ +HPT+I  ++++ALE  LE
Sbjct: 210 AAKSMIEVARTQDEETGDGTKSVIILAGEVLSVAEQFLEQQMHPTVIIAAYRQALEDTLE 389

Query: 147 IL-TDMSRPVQLSDRETLLNSAT 168
           +L T +  P+ +SDR  +LN  T
Sbjct: 390 VLRTKICTPIDISDRNQMLNIVT 458

 Score = 60.1 bits (144), Expect(2) = 2e-43,   Method: Compositional matrix adjust.
 Identities = 47/197 (23%), Positives = 98/197 (49%), Gaps = 3/197 (1%)
 Frame = +1

Query: 166 SATTSLNSKVVSQYSSLLSPMSVNAVMKV-IDPATATSVDLRDIKIVKKL-GGTIDDCEL 223
           S+ + L +K +S++  L   ++++A   V ++      +D++    V+K+ GGT+++ E+
Sbjct: 451 SSQSCLGTKFISKWMDLACQIALDATTTVFMEENGRKEIDIKRYAKVEKIPGGTMEESEV 630

Query: 224 VEGLVLTQKVANSGITR-VEKAKIGLIQFCLSAPKTDMDNQIVVSDYAQMDRVLREERAY 282
           ++G+ + + V +  + R +E  +I L+   L   K +    I +S      ++L+ E  Y
Sbjct: 631 LKGIXVNKDVVHXKMKRRIENPRIMLLDCNLEYKKGESATNIEISKEEDFAKILQLEEEY 810

Query: 283 ILNLVKQIKKTGCNVLLIQKSILRDALSDLALHFLNKMKIMVVKDVEREDIEFICKTIGT 342
           I  +  +I     ++++ +K +     SDLA HFL K  I V++ V + D   I +  G 
Sbjct: 811 IRKMCDEIIALKPDLVITEKGV-----SDLAQHFLLKAGISVLRRVRKTDNNRIARACGA 975

Query: 343 KPVAHIDQFTADMLGSA 359
                 D+   + +GS 
Sbjct: 976 TIANRTDELKEEDMGSG 1026
>09900
          Length = 1305

 Score =  157 bits (398), Expect = 8e-39,   Method: Compositional matrix adjust.
 Identities = 89/282 (31%), Positives = 159/282 (56%), Gaps = 2/282 (0%)
 Frame = +3

Query: 257 KTDMDN-QIVVSDYAQMDRVLREERAYILNLVKQIKKTGCNVLLIQKSILRDALSDLALH 315
           K++ DN ++ V +  +   ++  E   + + + +I ++G  V+L +  I      D+A  
Sbjct: 93  KSERDNAEVRVDNVQEYQSIVDAEWKILYDKLDKIHQSGAKVVLSKLPI-----GDVATQ 257

Query: 316 FLNKMKIMVVKDVEREDIEFICKTIGTKPVAHIDQFTADMLGSAELAEEVSLNGS-GKLF 374
           +     +     V  ED+    K  G      +   T D+LG+ +L +E+ + G    +F
Sbjct: 258 YFADRDMFCAGRVPEEDLRRTMKACGGSIQTTVQSLTPDVLGTCQLFDEIQIGGERFNMF 437

Query: 375 KITGCTSPGKTVTIVVRGSNKLVIEEAERSIHDALCVIRCLVKKRALIAGGGAPEIELAL 434
           K  GCT   +T TI++RG  +  +EE ERS+HDA+ ++R  +K  +++AGGGA E+E++ 
Sbjct: 438 K--GCTM-ARTCTIILRGGAEQFMEETERSLHDAIMIVRRAIKNDSVVAGGGAIEMEVSY 608

Query: 435 RLTEYSRTLSGMESYCVRAFADAMEVIPSTLAENAGLNPISTVTELRNRHAQGEKTTGIN 494
            L E+S T++G E   + A+A A+EVIP  L +NAG +  + + +LR +HAQG    G+N
Sbjct: 609 HLREHSHTIAGKEQLLMSAYAKALEVIPRQLCDNAGFDATNILNKLRQKHAQGGTWYGVN 788

Query: 495 VRKGGISNILEEMVVQPLLVSVSALTLATETVRSILKIDDVV 536
           + +  I++  E+ V +P +V ++ALT A+E    IL +D+ +
Sbjct: 789 ILREDIADNFEDCVWEPAVVKINALTAASEATALILSVDETI 914
>29864
          Length = 1026

 Score =  147 bits (370), Expect = 1e-35,   Method: Compositional matrix adjust.
 Identities = 88/261 (33%), Positives = 149/261 (57%), Gaps = 1/261 (0%)
 Frame = +1

Query: 37  NISAAKAVADAIRTSLGPKGMDKMIQDGKGDVTITNDGATILKQMQVLHPAARMLVELSK 96
           NI+AAK + D +R++LGPKG  KM+  G GD+ +T DG  +L +MQ+ HP A ++  ++ 
Sbjct: 175 NIAAAKGLQDVLRSNLGPKGTMKMLVSGAGDIKLTKDGNVLLHEMQIQHPTASLIARVAT 354

Query: 97  AQDIEAGDGTTSVVIIAGSLLDSCTKLLQKGIHPTIISESFQKALEKGLEILTDMSRPVQ 156
           AQD   GDGTTS V+I G LL      + +G+HP +I+E F+ A  K LE+L ++    +
Sbjct: 355 AQDDITGDGTTSNVLIIGELLKQADLYIAEGLHPRLITEGFELARNKALEVLEEVKVKRE 534

Query: 157 LSDRETLLNSATTSLNSKVVSQYSSLLSPMSVNAVMKVIDPATATSVDLRDIKIVKKLGG 216
           + DRETL+  A TSL +KV ++ + LL+   V+AV+ +  P     +DL  +++++    
Sbjct: 535 V-DRETLVQVARTSLRTKVHTELADLLTEHVVDAVLAIQXPGEG--IDLHMVELMEMQHK 705

Query: 217 TIDDCELVEGLVLTQKVANSGITRVEK-AKIGLIQFCLSAPKTDMDNQIVVSDYAQMDRV 275
           T  D  LV GLV+     +  + +  K A I      L   KT++++        + +++
Sbjct: 706 TDLDSTLVRGLVMDHGARHPDMKKHTKDAFILTCNVSLEYEKTEVNSGFFYKTAQEREKL 885

Query: 276 LREERAYILNLVKQIKKTGCN 296
           +  ER +I    ++++K  C+
Sbjct: 886 VEAERTFI---DERVRKNHCS 939
>02673
          Length = 1243

 Score = 79.3 bits (194), Expect = 3e-15,   Method: Compositional matrix adjust.
 Identities = 43/111 (38%), Positives = 71/111 (63%), Gaps = 1/111 (0%)
 Frame = +1

Query: 426 GAPEIELALRLTEYSRTLSGMESYCVRAFADAMEVIPSTLAENAGLNPISTVTELRNRHA 485
           GAPEI  ++ + E +  +S +E Y VR+F++A+E +P  LAEN+GL PI T+ E+++R  
Sbjct: 1   GAPEIAASVAVAEAADKISTLEQYAVRSFSEALEAVPLALAENSGLAPIQTLAEVKSRQV 180

Query: 486 QGEKTT-GINVRKGGISNILEEMVVQPLLVSVSALTLATETVRSILKIDDV 535
           + +    GI+    G +++ E+ V++ L      + LAT+ VR ILKIDD+
Sbjct: 181 KEKNPRLGIDCLLKGTNDMKEQNVIETLTAKKQQILLATQLVRMILKIDDI 333
>17249
          Length = 909

 Score = 65.1 bits (157), Expect = 7e-11,   Method: Compositional matrix adjust.
 Identities = 36/82 (43%), Positives = 51/82 (62%), Gaps = 1/82 (1%)
 Frame = +3

Query: 457 AMEVIPSTLAENAGLNPISTVTELRNRHAQGEKTT-GINVRKGGISNILEEMVVQPLLVS 515
           A+EVI  TL +N G N I T+T LR +HAQG+K T GI+   G I ++ E  + +PL V 
Sbjct: 12  ALEVISRTLIQNCGANTIRTLTALRAKHAQGQKNTWGIDGNTGNIVDMAEFGIWEPLSVK 191

Query: 516 VSALTLATETVRSILKIDDVVN 537
           +     A ET   +L+IDD+V+
Sbjct: 192 LQVYKTACETAILLLRIDDIVS 257
>30661
          Length = 380

 Score = 64.3 bits (155), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 41/107 (38%), Positives = 63/107 (58%)
 Frame = +3

Query: 356 LGSAELAEEVSLNGSGKLFKITGCTSPGKTVTIVVRGSNKLVIEEAERSIHDALCVIRCL 415
           LG  +L EEV + G  KL K +G  + G+  TIV+RG+ + +++EA RS+HDALCV+   
Sbjct: 75  LGQCDLIEEVMI-GEDKLIKFSG-VALGEACTIVLRGATQQILDEAXRSLHDALCVLSQT 248

Query: 416 VKKRALIAGGGAPEIELALRLTEYSRTLSGMESYCVRAFADAMEVIP 462
           VK+   + GGG  E+ +A  +++ +    G E       A AME +P
Sbjct: 249 VKETRTVYGGGCSEMLMAEAVSQLAAKTPGKE-------AIAMEALP 368
>29327
          Length = 2425

 Score = 63.5 bits (153), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 31/40 (77%), Positives = 37/40 (92%)
 Frame = +1

Query: 497 KGGISNILEEMVVQPLLVSVSALTLATETVRSILKIDDVV 536
           +G I+NILEE V+QPLLVS SA+TLA+ETVRSILKIDD+V
Sbjct: 163 QGAITNILEENVLQPLLVSTSAITLASETVRSILKIDDIV 282
>34332
          Length = 714

 Score = 36.6 bits (83), Expect = 0.024,   Method: Compositional matrix adjust.
 Identities = 15/31 (48%), Positives = 21/31 (67%)
 Frame = -1

Query: 426 GAPEIELALRLTEYSRTLSGMESYCVRAFAD 456
           G  EIELA ++T Y  +L G+E Y V+ FA+
Sbjct: 93  GGKEIELAKQITTYGESLPGLEQYAVKKFAE 1
>10291
          Length = 1066

 Score = 32.0 bits (71), Expect = 0.57,   Method: Compositional matrix adjust.
 Identities = 18/45 (40%), Positives = 27/45 (60%)
 Frame = +1

Query: 491 TGINVRKGGISNILEEMVVQPLLVSVSALTLATETVRSILKIDDV 535
           TG  V   G +++ E+ V++ L      + LAT+ VR ILKIDD+
Sbjct: 4   TGKGVGCRGTNDMKEQNVIETLTAKKQQILLATQLVRMILKIDDI 138
>16801
          Length = 1085

 Score = 29.6 bits (65), Expect = 3.5,   Method: Compositional matrix adjust.
 Identities = 16/43 (37%), Positives = 25/43 (58%), Gaps = 3/43 (6%)
 Frame = -2

Query: 264 IVVSDYAQMDRVLREERAYI---LNLVKQIKKTGCNVLLIQKS 303
           I+V+   Q+ ++ + E  Y    L L+KQIK  GCNV +  +S
Sbjct: 505 ILVNIVCQLPKIYQGENLYFTGQLVLIKQIKICGCNVSVFSQS 377
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|120407050|ref|NP_061356.2| nucleolar protein 5 [Mus
musculus]
         (536 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

02001                                                                 488   e-138
10550                                                                 306   2e-83
05297                                                                 104   1e-22
00700                                                                  69   5e-12
>02001
          Length = 4146

 Score =  488 bits (1257), Expect = e-138,   Method: Compositional matrix adjust.
 Identities = 254/454 (55%), Positives = 339/454 (74%), Gaps = 7/454 (1%)
 Frame = -1

Query: 1    MLVLFETSVGYAIFKVLNEKKLQEVDSLWKEFETPEKANKIVKLKHFEKFQDTAEALAAF 60
            MLVLFET+ GYA+FK+L EKKL+  ++L+++FE  E AN+IVKLK F+KFQD + AL+A 
Sbjct: 4089 MLVLFETASGYAVFKLLKEKKLKHSENLFQDFENAESANEIVKLKRFQKFQDMSTALSAA 3910

Query: 61   TALMEGXXXX-XXXXXXXXXXXEAHEPLAVADAKLGGVIKEKLNLSCIHSPVVNELMRGI 119
            TA  EG                +A E LAVADAKLG +IKE+ N+ C+ +  +NELMR I
Sbjct: 3909 TAAFEGHISAPLKKLLKKLVSKDAQEELAVADAKLGNLIKEEFNIQCVANNNINELMRCI 3730

Query: 120  RSQMDGLIPGVEPREMAAMCLGLAHSLSRYRLKFSADKVDTMIVQAISLLDDLDKELNNY 179
            RSQ+D L   V  +++ AM LGLAHSLSRY++KFS DKVDTMIVQAIS LDD+DKE+NNY
Sbjct: 3729 RSQLDNL---VSDKDLHAMSLGLAHSLSRYKVKFSPDKVDTMIVQAISTLDDIDKEINNY 3559

Query: 180  IMRCREWYGWHFPELGKIISDNLTYCKCLQKVGDRKNYXXXXXXXXXXXXXXXXXXXXXX 239
             MR REWY WHFPEL K+++++  + + + K+G+++N                       
Sbjct: 3558 HMRAREWYAWHFPELPKVVTEHEAFIRTVMKLGNKQNATSCDLSDILPEEVETDVKEAAE 3379

Query: 240  ISMGTEVSEEDICNILHLCTQVIEISEYRTQLYEYLQNRMMAIAPNVTVMVGELVGARLI 299
            ISMGTE+S++D+  I++LC Q++ + EYR QL+EYL++RM AIAPN+TV+VGELVGARLI
Sbjct: 3378 ISMGTEISDDDLTVIMYLCKQIVSLVEYRGQLFEYLKHRMGAIAPNLTVLVGELVGARLI 3199

Query: 300  AHAGSLLNLAKHAASTVQILGAEKALFRALKSRRDTPKYGLIYHASLVGQSSPKHKGKIS 359
            +HAGSL+NLAKH ASTVQILGAEKALFRALKS+ DTPKYGLIYHASLVGQ++PK+KGK+S
Sbjct: 3198 SHAGSLMNLAKHPASTVQILGAEKALFRALKSKHDTPKYGLIYHASLVGQANPKNKGKLS 3019

Query: 360  RMLAAKTVLAIRYDAFGEDSSSA--MGIENRAKLEARLRILEDRGIRKISGTGKALAKAE 417
            RMLAAK+ LA R DA G+++++   +G  ++ KL+ R+R LE+RG+++ISG GK     +
Sbjct: 3018 RMLAAKSSLAARVDALGDENTTQKDIGAVHKLKLDMRIRQLENRGVQRISGRGKEGRTPQ 2839

Query: 418  KYEHKSEVKTYDPSGDSTLPTC----SKKRKIEE 447
            +YE+ SEV+TY+ + DSTLP+     SKKRK+E+
Sbjct: 2838 RYENISEVRTYNTAADSTLPSVSPSGSKKRKVED 2737
>10550
          Length = 1765

 Score =  306 bits (784), Expect = 2e-83,   Method: Compositional matrix adjust.
 Identities = 170/412 (41%), Positives = 242/412 (58%), Gaps = 13/412 (3%)
 Frame = -2

Query: 1    MLVLFETSVGYAIFKVLNEKKLQEVDSLWKEFETP----EKANKIVKLKHFEKFQDTAEA 56
            + VLFE +VGYA+F+V   K+  E+  L    E       K N +VK +    F +   A
Sbjct: 1737 LYVLFEHAVGYALFQV---KEFDELALLAPRVEQNVLDLSKFNSVVKFEALAAFTNAHNA 1567

Query: 57   LAAFTALMEGXXXXXXXXXXXXXXXEAHEPLAV----ADAKLGGVIKEKLNLSCIHSPVV 112
            L     + EG               ++ + L V    AD+KL   I E L++SC+ + V+
Sbjct: 1566 LDNINCVSEGVLHEDLRTLLAKHVPKSSKKLKVMLGLADSKLAAAIVEALDISCVTTGVI 1387

Query: 113  NELMRGIRSQMDGLIPGVEPREMAA--MCLGLAHSLSRYRLKFSADKVDTMIVQAISLLD 170
             +++RGIR     L+   +  E  A    LGL HS SR ++KF+  +VD MI+Q+I+LLD
Sbjct: 1386 PDILRGIRMHFAKLVGQHKLNEGTASKAQLGLGHSYSRAKVKFNVHRVDNMIIQSIALLD 1207

Query: 171  DLDKELNNYIMRCREWYGWHFPELGKIISDNLTYCKCLQKVGDRKNY---XXXXXXXXXX 227
             LDK++N + MR REWY +HFPEL KI+ DN  Y + +Q + DRK               
Sbjct: 1206 QLDKDINTFSMRIREWYSYHFPELVKIVPDNYLYARTVQVIQDRKQMPEDNSQLEELLMD 1027

Query: 228  XXXXXXXXXXXXISMGTEVSEEDICNILHLCTQVIEISEYRTQLYEYLQNRMMAIAPNVT 287
                        +SMG +++  D+ NI  LC +VI +SE+R +L +YL +RM ++APN+ 
Sbjct: 1026 SAKCQAVLDAARVSMGMDIAPIDLINIQALCARVIGLSEFRKELSQYLMDRMQSVAPNLA 847

Query: 288  VMVGELVGARLIAHAGSLLNLAKHAASTVQILGAEKALFRALKSRRDTPKYGLIYHASLV 347
             ++G+ VGARLIAHAGSL NLAK  ASTVQILGAEKALFRALK++ +TPKYGLI+H++ +
Sbjct: 846  ALIGDQVGARLIAHAGSLTNLAKCPASTVQILGAEKALFRALKTKGNTPKYGLIFHSTFI 667

Query: 348  GQSSPKHKGKISRMLAAKTVLAIRYDAFGEDSSSAMGIENRAKLEARLRILE 399
            G++  K+KG+ISR LA K  +A R D F +  SS  G   R ++E RL+  E
Sbjct: 666  GRAGAKNKGRISRYLANKCSIASRIDCFSDMPSSIFGDHLRQQVEDRLKFFE 511
>05297
          Length = 530

 Score =  104 bits (259), Expect = 1e-22,   Method: Compositional matrix adjust.
 Identities = 51/153 (33%), Positives = 88/153 (57%)
 Frame = +2

Query: 243 GTEVSEEDICNILHLCTQVIEISEYRTQLYEYLQNRMMAIAPNVTVMVGELVGARLIAHA 302
           GTE+S+ED+ ++   C   + +SE +  ++EY+++RM  IAPN++++VG  + A+L+  A
Sbjct: 5   GTELSDEDLMSVSEACDTAVGLSESKKHIFEYVESRMTFIAPNLSIIVGASIAAKLMGIA 184

Query: 303 GSLLNLAKHAASTVQILGAEKALFRALKSRRDTPKYGLIYHASLVGQSSPKHKGKISRML 362
           G L  L+K  A  + +LG++K       +    P  G IY++  V +  P  + K +R+L
Sbjct: 185 GGLTYLSKMPADNIILLGSQKRTLSGFSTTAILPHTGFIYYSDTVQKLPPDLRRKAARLL 364

Query: 363 AAKTVLAIRYDAFGEDSSSAMGIENRAKLEARL 395
           A KT L  R D F       +G + RA++E +L
Sbjct: 365 AGKTALCARVDGFHGSVDGKVGDDLRAEVEGKL 463
>00700
          Length = 1051

 Score = 68.9 bits (167), Expect = 5e-12,   Method: Compositional matrix adjust.
 Identities = 42/189 (22%), Positives = 85/189 (44%), Gaps = 3/189 (1%)
 Frame = +1

Query: 155 ADKVDTMIVQAISLLDDLDKELNNYIMRCREWYGWHFPELGKIISDNLTYCKCLQKVGDR 214
           AD    +IV A ++  ++D E+N      ++ Y   FPEL  ++   + Y   ++++G+ 
Sbjct: 286 ADPEYKLIVDANNMTVEIDNEINVIHQFVKDVYNKRFPELESLVPTAMEYISTVKELGNN 465

Query: 215 ---KNYXXXXXXXXXXXXXXXXXXXXXXISMGTEVSEEDICNILHLCTQVIEISEYRTQL 271
              K+                        + GTE+S+ED+ ++   C   + +SE +  +
Sbjct: 466 ILEKSKNNEALQEILTSATIMVVSVTASTTQGTELSDEDLMSVSEACDTAVGLSESKKHI 645

Query: 272 YEYLQNRMMAIAPNVTVMVGELVGARLIAHAGSLLNLAKHAASTVQILGAEKALFRALKS 331
           +EY+++RM  IAPN++++VG  +               + AA  + +LG++K       +
Sbjct: 646 FEYVESRMTFIAPNLSIIVGASIA-------------VQXAADNIILLGSQKRTLSGFST 786

Query: 332 RRDTPKYGL 340
               P + L
Sbjct: 787 TAILPPHRL 813
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|33469023|ref|NP_083087.1| elongation protein 3
homolog [Mus musculus]
         (547 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

11276                                                                 483   e-137
>11276
          Length = 1229

 Score =  483 bits (1244), Expect = e-137,   Method: Compositional matrix adjust.
 Identities = 238/280 (85%), Positives = 259/280 (92%)
 Frame = +3

Query: 267 ACESFHLAKDSGFKVVTHMMPDLPNVGLERDIEQFIEFFENPAFRPDGLKLYPTLVIRGT 326
            CESF ++KD+GFKVV HMMPDLPNVG ERD+EQFIE+FENPAFR DGLK+YPTLVIRGT
Sbjct: 3   VCESFQMSKDAGFKVVAHMMPDLPNVGWERDVEQFIEYFENPAFRSDGLKIYPTLVIRGT 182

Query: 327 GLYELWKSGRYRSYSPSDLIELVARILALVPPWTRVYRVQRDIPMPLVSSGVEHGNLREL 386
           GLYELWK+GRY+SY PS L++L+ARILALVPPWTRVYRVQRDIPMPLVSSGVE GNLREL
Sbjct: 183 GLYELWKTGRYKSYPPSMLVDLIARILALVPPWTRVYRVQRDIPMPLVSSGVERGNLREL 362

Query: 387 AFARMKDLGIQCRDVRTREVGIQEIHHRVRPYQVELVRRDYVANGGWETFLSYEDPDQDI 446
           A ARM DLG +CRDVRTREVGIQEIHH+V+PY+ EL+RRDYVANGGWETFLSYEDP+QDI
Sbjct: 363 ALARMADLGTKCRDVRTREVGIQEIHHKVKPYEAELIRRDYVANGGWETFLSYEDPEQDI 542

Query: 447 LIGLLRLRKCSEETFRFELGGGVSIVRELHVYGSVVPVSSRDPTKFQHQGFGMLLMEEAE 506
           LIGLLRLRKCS +TFR EL GG SIVRELHVYGSVVPV +RDPTKFQHQGFGMLLMEEAE
Sbjct: 543 LIGLLRLRKCSPDTFRPELVGGCSIVRELHVYGSVVPVHARDPTKFQHQGFGMLLMEEAE 722

Query: 507 RIAREEHGSGKMAVISGVGTRNYYRKIGYRLQGPYMVKML 546
           RIAREEHGS K+AVISGVGTRNYYRKIGY L+GPYM K L
Sbjct: 723 RIAREEHGSNKIAVISGVGTRNYYRKIGYELEGPYMTKPL 842
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6679891|ref|NP_032086.1| alpha glucosidase 2 alpha
neutral subunit [Mus musculus]
         (966 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

02103                                                                 484   e-137
22798                                                                  69   7e-12
21286                                                                  59   7e-09
26869                                                                  52   1e-06
10523                                                                  31   2.8  
12065                                                                  31   2.8  
30930                                                                  30   4.9  
>02103
          Length = 4227

 Score =  484 bits (1247), Expect = e-137,   Method: Compositional matrix adjust.
 Identities = 227/439 (51%), Positives = 302/439 (68%), Gaps = 1/439 (0%)
 Frame = -2

Query: 528  SASYPDFTNPRMRAWWSNMFSFDNYEGSAPNLYVWNDMNEPSVFNGPEVTMLKDAVHYGG 587
            S+ +PDF    +R WW++ FS   Y GS  NLYVWNDMNEPSVFN PE+TM +D  H  G
Sbjct: 4226 SSGWPDFLESHVREWWADKFSLSEYVGSDLNLYVWNDMNEPSVFNAPEITMNRDVKHLAG 4047

Query: 588  WEHRDIHNIYGLYVHMATADGLIQRSGGIERPFVLSRAFFSGSQRFGAVWTGDNTAEWDH 647
            WE+R++HNIYG++VH AT DGL++R+   ER FVL+RAFFSG+QR  AVWTGDN  EW H
Sbjct: 4046 WENREVHNIYGMHVHAATMDGLLKRTNYQERAFVLTRAFFSGTQRTSAVWTGDNMGEWSH 3867

Query: 648  LKISIPMCLSLALVGLSFCGADVGGFFKNPEPELLVRWYQMGAYQPFFRAHAHLDTGRRE 707
            LKIS PM +SL LVG++F GADVGGFF+NP+ EL+ RWYQ GA+QPFFRAHAHLDT RRE
Sbjct: 3866 LKISNPMIMSLNLVGITFSGADVGGFFRNPDNELITRWYQAGAFQPFFRAHAHLDTKRRE 3687

Query: 708  PWLLASQYQDAIRDALFQRYSLLPFWYTLFYQAHKEGFPVMRPLWVQYPEDMSTFSIEDQ 767
            P+LL  +  + IR AL  RYS LP+WYT+F  + K+G  VMRPLWV++P++ +TF I+D 
Sbjct: 3686 PYLLPDENVNIIRAALRARYSYLPYWYTVFASSEKDGAAVMRPLWVEFPKERATFGIDDN 3507

Query: 768  FMLGDALLIHPVSDAGAHGVQVYLPGQEEVWYDIQSYQKHHGPQTLYLPVTLSSIPVFQR 827
            FM+G +LL+ PV+D GA    VY PG +++WYD+++++ + G Q + +   LS IPV+QR
Sbjct: 3506 FMVGSSLLVRPVTDQGATNANVYFPGADQIWYDVETHEAYKGQQEVNVAAPLSKIPVYQR 3327

Query: 828  GGTIVPRWMRVRRSSDCMKDDPITLFVALSPQGTAQGELFLDDGHTFNYQTRHEFLLRRF 887
            GG+I+PR MR RRSS  M DDP+TL VAL  +  AQG+L++DD H+FNY+    + +  +
Sbjct: 3326 GGSIIPRKMRPRRSSSLMFDDPLTLVVALDSKQEAQGQLYVDDYHSFNYKN-GAYGIIDY 3150

Query: 888  XXXXXXXXXXXADPKGHLETPIWIERVVIMGA-GKPAAVVLQTKGSPESRLSFQHDPETS 946
                               T  W+ERVV++G   +P  V L   G   + L+F  D    
Sbjct: 3149 SFTSHKLHSNVKHEGAQFTTKEWLERVVVVGLPHEPRKVTLHKSGQ-TTDLTFTFDSSRK 2973

Query: 947  VLILRKPGVSVASDWSIHL 965
            VL +RKPG ++   W+I L
Sbjct: 2972 VLTIRKPGTNILQTWTISL 2916
>22798
          Length = 482

 Score = 69.3 bits (168), Expect = 7e-12,   Method: Compositional matrix adjust.
 Identities = 55/165 (33%), Positives = 77/165 (46%), Gaps = 29/165 (17%)
 Frame = +2

Query: 529 ASYPDFTNPRMRAWWSNMFSFDNYEGSAPNLYVWNDMNEPSVF----------------- 571
            ++PDF +P +  +W N     +Y    P   +W DMNE S F                 
Sbjct: 5   TAFPDFFHPNVDQYWYNQMK--SYHDMIPYDGIWLDMNEVSNFIDGSTHGCTKGSLDRPP 178

Query: 572 ------NGPEV---TML---KDAVHYGGWEHRDIHNIYGLYVHMATADGLIQRSGGIERP 619
                 NG  +   TM    K AV     ++ ++HN+YG     +T  GL +  G  +R 
Sbjct: 179 YVPPTINGKSLYAKTMCPSAKQAVS----DNYNLHNMYGWSEMRSTRAGLTKLFG--KRS 340

Query: 620 FVLSRAFFSGSQRFGAVWTGDNTAEWDHLKISIPMCLSLALVGLS 664
           F+LSR+ FSGS  FGA WTGD  +EW  L  SIP  L+  + G+S
Sbjct: 341 FILSRSTFSGSGHFGAHWTGDIRSEWSDLYYSIPSILNSNMFGMS 475
>21286
          Length = 1212

 Score = 59.3 bits (142), Expect = 7e-09,   Method: Compositional matrix adjust.
 Identities = 32/104 (30%), Positives = 54/104 (51%), Gaps = 1/104 (0%)
 Frame = +3

Query: 391 GPSVFDVFRQYASLTGTQALPPLFSLGYHQSRWNYRDEADVLEVDQGFDDHNMPCDVIWL 450
           GPS   V  QY SL G   +PP +SLG+H  ++ Y     + EV        +P DV W 
Sbjct: 798 GPSPLQVVEQYVSLIGRPVMPPFWSLGFHLCKYGYGSSKVLSEVIARNRAAKIPYDVQWN 977

Query: 451 DIEHADGKRYFTWDPT-RFPQPLNMLEHLASKRRKLVAIVDPHI 493
           DI++ D  + +T+D    +    ++++ L +  ++ + I+DP I
Sbjct: 978 DIDYMDAYKDWTYDSNGSYSGLRDIVDDLHAHNQRYIMIIDPGI 1109
>26869
          Length = 390

 Score = 52.4 bits (124), Expect = 1e-06,   Method: Composition-based stats.
 Identities = 34/100 (34%), Positives = 48/100 (48%), Gaps = 1/100 (1%)
 Frame = +3

Query: 731 PFWYTLFYQAHKEGFPVMRPLWVQYPEDMSTFSIEDQFMLGDALLIHPVSDAGAHGVQVY 790
           P+    F +A + G PV  PLW   P D    SI D+F+LGD ++  PV   GA    +Y
Sbjct: 15  PYIMKTFKRAVETGEPVNAPLWWISPNDAIAQSIYDEFLLGDDIIAAPVVVEGATNRDIY 194

Query: 791 LPGQEEVWYDIQSYQKHHGP-QTLYLPVTLSSIPVFQRGG 829
           LP  E  W D  +   + GP   +     L+++P F   G
Sbjct: 195 LPEGE--WIDGNTNDVYKGPVWIMEYTAPLNTLPYFCEKG 308
>10523
          Length = 353

 Score = 30.8 bits (68), Expect = 2.8,   Method: Composition-based stats.
 Identities = 12/23 (52%), Positives = 17/23 (73%)
 Frame = +1

Query: 120 VADPPTARLSVSGRDDNSVELTV 142
           ++ PPT  LSVS RD+N + LT+
Sbjct: 94  ISSPPTTILSVSSRDENGLGLTI 162
>12065
          Length = 1251

 Score = 30.8 bits (68), Expect = 2.8,   Method: Composition-based stats.
 Identities = 12/23 (52%), Positives = 17/23 (73%)
 Frame = +1

Query: 120 VADPPTARLSVSGRDDNSVELTV 142
           ++ PPT  LSVS RD+N + LT+
Sbjct: 88  ISSPPTTILSVSSRDENGLGLTI 156
>30930
          Length = 1452

 Score = 30.0 bits (66), Expect = 4.9,   Method: Compositional matrix adjust.
 Identities = 37/120 (30%), Positives = 48/120 (40%), Gaps = 2/120 (1%)
 Frame = -3

Query: 294  EGGEPYRLY--NLDVFQYELNNPMALYGSVPVLLAHSFHRDLGIFWLNAAETWVDISSNT 351
            EG    RL   N+DV Q ++ N     G V    A  F  +     L     W  +  N 
Sbjct: 1246 EGAAQLRLTSPNIDVIQLDVTND----GQVEE--ARRFXDE----QLQGYGLWAIV--NN 1103

Query: 352  AGKTLFGKMLDYLQGSGETPQTDIRWMSESGIIDVFLMLGPSVFDVFRQYASLTGTQALP 411
            AG TLFG  +++   S      D+ W+    I   FL    SV       ASL+G  ALP
Sbjct: 1102 AG-TLFGAEVEWCSLSRXQRMMDVNWLGTVRITQAFLPYVRSVKGRVINVASLSGRVALP 926
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|112293264|ref|NP_031978.2| protein
disulfide-isomerase A3 [Mus musculus]
         (505 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

06936                                                                 482   e-136
03582                                                                 144   6e-52
28335                                                                 172   2e-43
35310                                                                 103   1e-22
35861                                                                 100   3e-21
14392                                                                  84   9e-17
18455                                                                  82   7e-16
18943                                                                  74   2e-13
04510                                                                  70   2e-12
30644                                                                  52   9e-11
21509                                                                  55   7e-08
36159                                                                  54   2e-07
07257                                                                  46   4e-05
15159                                                                  45   8e-05
04779                                                                  44   1e-04
01000                                                                  44   1e-04
>06936
          Length = 2198

 Score =  482 bits (1240), Expect = e-136,   Method: Compositional matrix adjust.
 Identities = 249/466 (53%), Positives = 318/466 (68%), Gaps = 5/466 (1%)
 Frame = +3

Query: 26  DVLELTDENFESRVSDTGSAGLMLVEFFAPWCGHCKRLAPEYEAAATRL---KGIVPLAK 82
           DVL+L   +F+S +       LMLVEFFAPWCGHCK+LAP+YE AAT L      VPLAK
Sbjct: 147 DVLDLKKSDFQSTIE---KHSLMLVEFFAPWCGHCKKLAPQYELAATALLKNDPPVPLAK 317

Query: 83  VDCTANTNTCNKYGVSGYPTLKIFRDGEEAGAYDGPRTADGIVSHLKKQAGPASVPLRTE 142
           VDCT  T+ C+KYGVSGYPTLK+FR GE    YDGPR  DGIV ++ K AGP S  L++ 
Sbjct: 318 VDCTEETDVCSKYGVSGYPTLKVFRGGEVNKDYDGPRDKDGIVKYMAKMAGPTSKELKSV 497

Query: 143 EEFKKFISDKDASVVGFFRDLFSDGHSEFLKAASNLRDNYRFAHTNIESLVKEYDDNGEG 202
           EE++KF+S   + VVGFF    S G ++ LK  ++  D  RF +T   S V E     + 
Sbjct: 498 EEYEKFLSRDGSCVVGFFTGANS-GMADTLKKVADSEDGLRFGYTT-SSEVLEKAKYKDE 671

Query: 203 ITIFRPLHLANKFEDKTVAYTEKKMTSGKIKKFIQDSIFGLCPHMTEDNKDLIQGKDLLT 262
           I +FRP  +ANKFED  V +T     S  IKKF+++  FGLC   T DN    + K ++ 
Sbjct: 672 IVLFRPQKMANKFEDTAVKFT-GDANSHNIKKFLKEESFGLCALRTMDNAADFK-KPVVI 845

Query: 263 AYYDVDYEKNAKGSNYWRNRVMMVAKKFLDAGHKLNFAVASRKTFSHELSDFGLESTT-- 320
           A++DVDY KNAKGSNYWRNRVM V KK  D G K+NFAV+++  F +EL + GL+     
Sbjct: 846 AFFDVDYVKNAKGSNYWRNRVMKVGKKLRDEGLKINFAVSNKNEFDNELVECGLKEAVDA 1025

Query: 321 GEVPVVAIRTAKGEKFVMQEEFSRDGKALEQFLQEYFDGNLKRYLKSEPIPESNEGPVKV 380
            + P +     K +KF M +EF+ D    EQF+++  DG L+ Y+KSEP+P+++E  VKV
Sbjct: 1026SDKPAICAYNDKNQKFKMDQEFAMD--TFEQFVRDMLDGKLEAYMKSEPVPDNSENAVKV 1199

Query: 381 VVAENFDDIVNEEDKDVLIEFYAPWCGHCKNLEPKYKELGEKLSKDPNIVIAKMDATAND 440
            V  NF+++VN+ +KDVLIEFYAPWCGHCK L PKY EL EKL  +P IVIAKMDATAND
Sbjct: 1200AVGRNFEELVNDPEKDVLIEFYAPWCGHCKTLAPKYDELAEKLKNEPEIVIAKMDATAND 1379

Query: 441 VPSPYEVKGFPTIYFSPANKKLTPKKYEGGRELNDFISYLQREATN 486
           VP PY+V+GFPT+YF+P   K +PKKYEGGRE+NDF+ YL +EATN
Sbjct: 1380VPPPYDVRGFPTLYFAPKGSKSSPKKYEGGREVNDFVKYLAKEATN 1517
>03582
          Length = 1967

 Score =  144 bits (364), Expect(2) = 6e-52,   Method: Compositional matrix adjust.
 Identities = 108/367 (29%), Positives = 187/367 (50%), Gaps = 10/367 (2%)
 Frame = +3

Query: 129 KKQAGPASVPLRTEEEFKKFISDKDASVVGFFRDLFSDGHSEFLKAASNLRDNYRFAHTN 188
           +++ GP +  L+ ++E K F    +  V+GFF+D  S+G   F +AA+ + D+  F  T+
Sbjct: 420 EEKTGPPAEDLKDKDEAKAFAEKDEVVVIGFFKDQKSEGAVAFTEAAAGI-DDIPFGITS 596

Query: 189 IESLVKEYDDNGEGITIFRPLHLANKFEDKTVAYTEKKMTSGKIKKFIQDSIFGLCPHMT 248
            ES  KEY  + +GI + +      KF++    + E       I K ++D+   L    T
Sbjct: 597 DESAFKEYKMDKDGIVLLK------KFDEGRNDF-EGDFEPAAIIKHVRDNQLPLVVEFT 755

Query: 249 EDNKDLIQG---KDLLTAYYDVD-----YEKNAKGSNYWRNRVMMVAKKFLDAGHKLNFA 300
           +++   I G   K+ +  +   D      EK    +  ++ +V+ +   +LD     N  
Sbjct: 756 QESAQKIFGGEVKNHILLFLKKDGGEDTIEKFKAAAGDFKGKVLFI---YLDTDDAENGR 926

Query: 301 VASRKTFSHELSDFGLESTTGEVPVV-AIRTAKGEKFVMQEEFSRDGKALEQFLQEYFDG 359
           +            FGL+    E+P V  I+ A+       E    D + +++F+Q++ DG
Sbjct: 927 ITEF---------FGLKDE--EIPAVRLIQLAEDMTKYKPESADLDTETIKKFVQDFLDG 1073

Query: 360 NLKRYLKSEPIPESNEG-PVKVVVAENFDDIVNEEDKDVLIEFYAPWCGHCKNLEPKYKE 418
            L  +L SE +P   +  PVKV+V +NF ++  ++ K V +EFYAPWCGHCK L P + E
Sbjct: 1074KLNAHLMSEDVPSDWDAKPVKVLVGKNFKEVALDKTKGVFVEFYAPWCGHCKQLAPIWDE 1253

Query: 419 LGEKLSKDPNIVIAKMDATANDVPSPYEVKGFPTIYFSPANKKLTPKKYEGGRELNDFIS 478
           L +K +   ++VIAKMD+TAN++    +V+ FPT+ + P +       Y G R L+ F+ 
Sbjct: 1254LADKFTDKADVVIAKMDSTANEI-EEVKVQSFPTLKYFPKDSDEVI-DYNGERTLDAFVK 1427

Query: 479 YLQREAT 485
           +++   T
Sbjct: 1428FVESGGT 1448

 Score = 78.2 bits (191), Expect(2) = 6e-52,   Method: Compositional matrix adjust.
 Identities = 44/81 (54%), Positives = 50/81 (61%), Gaps = 3/81 (3%)
 Frame = +2

Query: 27  VLELTDENFESRVSDTGSAGLMLVEFFAPWCGHCKRLAPEYEAAATRLK---GIVPLAKV 83
           V  LT +NF+S V +      +LVEF+APWCGHCK LAPEY  AA  LK     V LAKV
Sbjct: 119 VYVLTTKNFDSFVKENE---FVLVEFYAPWCGHCKALAPEYAKAAQTLKDENSDVKLAKV 289

Query: 84  DCTANTNTCNKYGVSGYPTLK 104
           D T  T+     GV GYPTLK
Sbjct: 290 DATIETSLGENMGVRGYPTLK 352

 Score = 70.5 bits (171), Expect(2) = 2e-13,   Method: Compositional matrix adjust.
 Identities = 42/94 (44%), Positives = 60/94 (63%), Gaps = 3/94 (3%)
 Frame = +2

Query: 372 ESNEGPVKVVVAENFDDIVNEEDKDVLIEFYAPWCGHCKNLEPKYKELGEKLSKDPN--I 429
           + +EG V V+  +NFD  V +E++ VL+EFYAPWCGHCK L P+Y +  + L KD N  +
Sbjct: 104 KQDEG-VYVLTTKNFDSFV-KENEFVLVEFYAPWCGHCKALAPEYAKAAQTL-KDENSDV 274

Query: 430 VIAKMDATA-NDVPSPYEVKGFPTIYFSPANKKL 462
            +AK+DAT    +     V+G+PT+ FS   K L
Sbjct: 275 KLAKVDATIETSLGENMGVRGYPTLKFSVMEKIL 376

 Score = 23.1 bits (48), Expect(2) = 2e-13,   Method: Compositional matrix adjust.
 Identities = 7/16 (43%), Positives = 12/16 (75%)
 Frame = +1

Query: 467 YEGGRELNDFISYLQR 482
           Y GGR+  D +S+L++
Sbjct: 379 YSGGRQAADIVSWLKK 426

 Score = 71.6 bits (174), Expect = 7e-13,   Method: Compositional matrix adjust.
 Identities = 41/103 (39%), Positives = 58/103 (56%), Gaps = 3/103 (2%)
 Frame = +3

Query: 30   LTDENFESRVSDTGSAGLMLVEFFAPWCGHCKRLAPEYEAAATRL--KGIVPLAKVDCTA 87
            L  +NF+    D      + VEF+APWCGHCK+LAP ++  A +   K  V +AK+D TA
Sbjct: 1140 LVGKNFKEVALDKTKG--VFVEFYAPWCGHCKQLAPIWDELADKFTDKADVVIAKMDSTA 1313

Query: 88   NTNTCNKYGVSGYPTLKIF-RDGEEAGAYDGPRTADGIVSHLK 129
              N   +  V  +PTLK F +D +E   Y+G RT D  V  ++
Sbjct: 1314 --NEIEEVKVQSFPTLKYFPKDSDEVIDYNGERTLDAFVKFVE 1436

 Score = 28.9 bits (63), Expect = 4.8,   Method: Compositional matrix adjust.
 Identities = 18/47 (38%), Positives = 24/47 (51%)
 Frame = +1

Query: 85  CTANTNTCNKYGVSGYPTLKIFRDGEEAGAYDGPRTADGIVSHLKKQ 131
           C        KYG +      IFR+G+++  Y G R A  IVS LKK+
Sbjct: 292 CNYRDQLGRKYGCTWISNP*IFRNGKDS-EYSGGRQAADIVSWLKKR 429
>28335
          Length = 601

 Score =  172 bits (437), Expect = 2e-43,   Method: Compositional matrix adjust.
 Identities = 80/126 (63%), Positives = 95/126 (75%)
 Frame = -2

Query: 361 LKRYLKSEPIPESNEGPVKVVVAENFDDIVNEEDKDVLIEFYAPWCGHCKNLEPKYKELG 420
           ++ YLKS+PIP++ EGPVK  V   FD IVN   KDVLIEFYAPWCGHC+ LEPKY EL 
Sbjct: 597 IQPYLKSQPIPQNEEGPVKTAVGRTFDKIVNNPKKDVLIEFYAPWCGHCQQLEPKYNELA 418

Query: 421 EKLSKDPNIVIAKMDATANDVPSPYEVKGFPTIYFSPANKKLTPKKYEGGRELNDFISYL 480
             L  +P+IV AK+DATAND P+PYEVKGFP IYFSP   K  PKKYEG RE++  + Y+
Sbjct: 417 TLLKDEPDIVXAKIDATANDTPTPYEVKGFPAIYFSPKRFKEFPKKYEGDREVDAMLKYI 238

Query: 481 QREATN 486
            REAT+
Sbjct: 237 AREATS 220

 Score = 66.2 bits (160), Expect = 3e-11,   Method: Compositional matrix adjust.
 Identities = 37/90 (41%), Positives = 54/90 (60%), Gaps = 5/90 (5%)
 Frame = -2

Query: 48  MLVEFFAPWCGHCKRLAPEYEAAATRLK---GIVPLAKVDCTANTNTCNKYGVSGYPTLK 104
           +L+EF+APWCGHC++L P+Y   AT LK    IV  AK+D TAN +T   Y V G+P + 
Sbjct: 489 VLIEFYAPWCGHCQQLEPKYNELATLLKDEPDIV-XAKIDATAN-DTPTPYEVKGFPAIY 316

Query: 105 IF--RDGEEAGAYDGPRTADGIVSHLKKQA 132
               R  E    Y+G R  D ++ ++ ++A
Sbjct: 315 FSPKRFKEFPKKYEGDREVDAMLKYIAREA 226
>35310
          Length = 601

 Score =  103 bits (258), Expect = 1e-22,   Method: Compositional matrix adjust.
 Identities = 71/205 (34%), Positives = 106/205 (51%), Gaps = 3/205 (1%)
 Frame = +3

Query: 139 LRTEEEFKKFISDKDASVVGFFRDLFSDGHSEFLKAASNLRDNYRFAHTNIESLVKE--Y 196
           L+   +F  F+     SVVG+F+++       F K A    D  RFA T    L++   Y
Sbjct: 3   LKDISDFNAFLDRPGTSVVGYFQNVKGYKARTFQKVADTYGD-LRFAFTTDPDLMQHAGY 179

Query: 197 DDNGEGITIFRPLHLANKFEDKTVAYTEKKMTSGKIKKFIQDSIFGLCPHMTEDNKDLIQ 256
            D+   + ++RP  +A+KFE+ +V +    +++  ++ F+     GLC   T  N   I+
Sbjct: 180 SDD---VVLYRPKVMASKFEESSVVFG-GDLSATTLRFFLDAQKLGLCGLRTPGNA--IK 341

Query: 257 GKD-LLTAYYDVDYEKNAKGSNYWRNRVMMVAKKFLDAGHKLNFAVASRKTFSHELSDFG 315
            K  L  AYY+VD+E+N   S YWRNRVM V KK  D G+  +FAV+S+     +L D G
Sbjct: 342 FKTPLFVAYYEVDFERNPSFSTYWRNRVMKVGKKIRDEGNNAHFAVSSKVDLKQDLEDCG 521

Query: 316 LESTTGEVPVVAIRTAKGEKFVMQE 340
           L    G+ PVV        KF M+E
Sbjct: 522 LADYYGDPPVVCAYDQFSRKFKMEE 596
>35861
          Length = 850

 Score = 99.8 bits (247), Expect = 3e-21,   Method: Compositional matrix adjust.
 Identities = 45/90 (50%), Positives = 64/90 (71%), Gaps = 1/90 (1%)
 Frame = +3

Query: 345 DGKALEQFLQEYFDGNLKRYLKSEPIPESNEG-PVKVVVAENFDDIVNEEDKDVLIEFYA 403
           D   + +F+Q++ DG LK +LKSE +PE  +  PVKV+V++NF ++  ++ KDV +EFYA
Sbjct: 474 DTATISKFVQDFMDGKLKPHLKSEEVPEDWDAKPVKVLVSKNFKEVALDKSKDVFVEFYA 653

Query: 404 PWCGHCKNLEPKYKELGEKLSKDPNIVIAK 433
           PWCGHCK L P + ELGEK     ++VIAK
Sbjct: 654 PWCGHCKQLVPIWDELGEKFQDSDDVVIAK 743

 Score = 42.4 bits (98), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 25/76 (32%), Positives = 37/76 (48%), Gaps = 2/76 (2%)
 Frame = +3

Query: 30  LTDENFESRVSDTGSAGLMLVEFFAPWCGHCKRLAPEYEAAATRLKGI--VPLAKVDCTA 87
           L  +NF+    D      + VEF+APWCGHCK+L P ++    + +    V +AK     
Sbjct: 585 LVSKNFKEVALDKSKD--VFVEFYAPWCGHCKQLVPIWDELGEKFQDSDDVVIAK----- 743

Query: 88  NTNTCNKYGVSGYPTL 103
           N     + G  G+P L
Sbjct: 744 NGLHGQRSGGGGHPEL 791
>14392
          Length = 468

 Score = 84.3 bits (207), Expect = 9e-17,   Method: Compositional matrix adjust.
 Identities = 40/74 (54%), Positives = 54/74 (72%)
 Frame = +2

Query: 412 LEPKYKELGEKLSKDPNIVIAKMDATANDVPSPYEVKGFPTIYFSPANKKLTPKKYEGGR 471
           L P Y+EL EKL +D ++ I KMDATANDVP  + V+GFPT+++ P + K  P  Y GGR
Sbjct: 2   LTPIYEELAEKL-QDEDVAIVKMDATANDVPPEFNVRGFPTLFWLPKDSKNKPVSYNGGR 178

Query: 472 ELNDFISYLQREAT 485
           EL+DFI Y+ +EA+
Sbjct: 179 ELDDFIKYIAKEAS 220
>18455
          Length = 499

 Score = 81.6 bits (200), Expect = 7e-16,   Method: Compositional matrix adjust.
 Identities = 42/112 (37%), Positives = 63/112 (56%), Gaps = 2/112 (1%)
 Frame = +2

Query: 27  VLELTDENFESRVSDTGSAGLMLVEFFAPWCGHCKRLAPEYEAAATRL--KGIVPLAKVD 84
           V++LT++ F   VS    +G   V+FFAPWC HC+RLAP +E  A  L  +    ++K+D
Sbjct: 146 VVDLTEDTFAKHVS----SGNHFVKFFAPWCSHCQRLAPIWEELAKALIKEPSATISKID 313

Query: 85  CTANTNTCNKYGVSGYPTLKIFRDGEEAGAYDGPRTADGIVSHLKKQAGPAS 136
           CT   + C  + V GYPTL    DG++   Y G R    + ++++K  G  S
Sbjct: 314 CTQYRSICQDFEVKGYPTLLWIEDGKKIEKYAGARDMVTLKTYVEKMIGAPS 469

 Score = 72.8 bits (177), Expect = 3e-13,   Method: Compositional matrix adjust.
 Identities = 39/143 (27%), Positives = 77/143 (53%), Gaps = 3/143 (2%)
 Frame = +2

Query: 343 SRDGKALEQFLQEYFDGNLKRYLKSEPIPESNEGPVKVVVAENFDDIVNEE--DKDVLIE 400
           +RD  A+  F+ +  +      L  + + + ++ P    V +  +D   +     +  ++
Sbjct: 29  TRDLPAITDFINQELNTPAVEDLSDQQLKDESQNPNVGKVVDLTEDTFAKHVSSGNHFVK 208

Query: 401 FYAPWCGHCKNLEPKYKELGEKLSKDPNIVIAKMDATA-NDVPSPYEVKGFPTIYFSPAN 459
           F+APWC HC+ L P ++EL + L K+P+  I+K+D T    +   +EVKG+PT+ +    
Sbjct: 209 FFAPWCSHCQRLAPIWEELAKALIKEPSATISKIDCTQYRSICQDFEVKGYPTLLWIEDG 388

Query: 460 KKLTPKKYEGGRELNDFISYLQR 482
           KK+  +KY G R++    +Y+++
Sbjct: 389 KKI--EKYAGARDMVTLKTYVEK 451
>18943
          Length = 1035

 Score = 73.6 bits (179), Expect = 2e-13,   Method: Compositional matrix adjust.
 Identities = 51/171 (29%), Positives = 85/171 (49%), Gaps = 17/171 (9%)
 Frame = +2

Query: 57  CGHCKRLA----------PEYEAAATRLK------GIVPLAKVDCTANTNTCNKYGVSGY 100
           CG C+ L           P ++ A+ ++       G V  AKVDC       ++Y +S Y
Sbjct: 170 CGVCQLLCRLVSLQSDSGPTFDEASRKISEEFTQPGKVLFAKVDCDKEVTIASQYRISKY 349

Query: 101 PTLKIFRDGEEAGA-YDGPRTADGIVSHLKKQAGPASVPLRTEEEFKKFISDKDASVVGF 159
           PTLK+FR+G+     + G R+AD + + ++++   + V   T ++ ++ +  K   V+G+
Sbjct: 350 PTLKLFRNGQMVKKEFRGQRSADALAAFIREELKDSVVDHNTLDKLEE-LDTKKRQVIGY 526

Query: 160 FRDLFSDGHSEFLKAASNLRDNYRFAHTNIESLVKEYDDNGEGITIFRPLH 210
           F    SD +  FL+ AS+LRDN  F +T +   V   +  G     FRP H
Sbjct: 527 FEAKESDNYKTFLRVASSLRDNCIF-NTAVGP-VSASERTGGDYVAFRPPH 673

 Score = 28.5 bits (62), Expect = 6.2,   Method: Compositional matrix adjust.
 Identities = 14/42 (33%), Positives = 22/42 (52%)
 Frame = +3

Query: 384 ENFDDIVNEEDKDVLIEFYAPWCGHCKNLEPKYKELGEKLSK 425
           +N + I++  D  V + FYA WC   + L P+  +  EK  K
Sbjct: 138 DNINTIISRNDV-VFVNFYADWCRFSQILAPRLMKPPEKYLK 260
>04510
          Length = 685

 Score = 70.5 bits (171), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 38/72 (52%), Positives = 44/72 (61%), Gaps = 3/72 (4%)
 Frame = +2

Query: 26  DVLELTDENFESRVSDTGSAGLMLVEFFAPWCGHCKRLAPEYEAAATRL---KGIVPLAK 82
           DVL+L   +F+S +       LMLVEFFAPWCGHCK+LAP+YE AAT L      VPLAK
Sbjct: 353 DVLDLKKSDFQSTIEKHS---LMLVEFFAPWCGHCKKLAPQYELAATALLKNDPPVPLAK 523

Query: 83  VDCTANTNTCNK 94
           V        C K
Sbjct: 524 VVLCLCYYVCLK 559

 Score = 50.4 bits (119), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 21/44 (47%), Positives = 30/44 (68%), Gaps = 1/44 (2%)
 Frame = +2

Query: 392 EEDKDVLIEFYAPWCGHCKNLEPKYKELGEKLSK-DPNIVIAKM 434
           E+   +L+EF+APWCGHCK L P+Y+     L K DP + +AK+
Sbjct: 395 EKHSLMLVEFFAPWCGHCKKLAPQYELAATALLKNDPPVPLAKV 526
>30644
          Length = 845

 Score = 51.6 bits (122), Expect(2) = 9e-11,   Method: Compositional matrix adjust.
 Identities = 23/52 (44%), Positives = 35/52 (67%), Gaps = 1/52 (1%)
 Frame = -3

Query: 26  DVLEL-TDENFESRVSDTGSAGLMLVEFFAPWCGHCKRLAPEYEAAATRLKG 76
           DV+ + TD+     +    SA L++  F+APWCG+CKR+ P++ AAAT +KG
Sbjct: 480 DVVHIDTDDGLTKLLKKDKSAALVM--FYAPWCGYCKRMKPDFAAAATEVKG 331

 Score = 32.7 bits (73), Expect(2) = 9e-11,   Method: Compositional matrix adjust.
 Identities = 20/80 (25%), Positives = 32/80 (40%), Gaps = 13/80 (16%)
 Frame = -1

Query: 94  KYGVSGYPTLKIFRDGEEAGAYDGPRTADGIVSHLKKQAG-------------PASVPLR 140
           +Y ++G+PTL  F  G+    Y G    DGI+S L                  P+ V   
Sbjct: 272 QYNITGFPTLYYFEKGKLKYRYGGENNKDGIISWLSNPKPPEEPKKEAEWSEEPSEVAHL 93

Query: 141 TEEEFKKFISDKDASVVGFF 160
            +  F  F+    + +V F+
Sbjct: 92  EDSNFDDFLKQHPSVLVMFY 33

 Score = 38.9 bits (89), Expect(2) = 1e-04,   Method: Compositional matrix adjust.
 Identities = 17/51 (33%), Positives = 28/51 (54%), Gaps = 4/51 (7%)
 Frame = -3

Query: 370 IPESNEGPVKVVVAENFDD----IVNEEDKDVLIEFYAPWCGHCKNLEPKY 416
           IP   +     VV  + DD    ++ ++    L+ FYAPWCG+CK ++P +
Sbjct: 510 IPWDEDPTATDVVHIDTDDGLTKLLKKDKSAALVMFYAPWCGYCKRMKPDF 358

 Score = 24.3 bits (51), Expect(2) = 1e-04,   Method: Compositional matrix adjust.
 Identities = 13/40 (32%), Positives = 20/40 (50%)
 Frame = -1

Query: 441 VPSPYEVKGFPTIYFSPANKKLTPKKYEGGRELNDFISYL 480
           V + Y + GFPT+Y+    K     +Y G    +  IS+L
Sbjct: 281 VQAQYNITGFPTLYYFEKGK--LKYRYGGENNKDGIISWL 168

 Score = 42.7 bits (99), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 21/41 (51%), Positives = 26/41 (63%), Gaps = 2/41 (4%)
 Frame = -1

Query: 372 ESNEGPVKVVVAE--NFDDIVNEEDKDVLIEFYAPWCGHCK 410
           E +E P +V   E  NFDD + +    VL+ FYAPWCGHCK
Sbjct: 128 EWSEEPSEVAHLEDSNFDDFLKQH-PSVLVMFYAPWCGHCK 9

 Score = 38.9 bits (89), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 17/37 (45%), Positives = 23/37 (62%)
 Frame = -1

Query: 26  DVLELTDENFESRVSDTGSAGLMLVEFFAPWCGHCKR 62
           +V  L D NF+  +    S   +LV F+APWCGHCK+
Sbjct: 107 EVAHLEDSNFDDFLKQHPS---VLVMFYAPWCGHCKK 6

 Score = 32.0 bits (71), Expect = 0.53,   Method: Compositional matrix adjust.
 Identities = 29/106 (27%), Positives = 47/106 (44%), Gaps = 12/106 (11%)
 Frame = -3

Query: 67  YEAAATRLKGIVPLAKVDCTANTNTCNKYGVSGYP-TLKIFRDGEEAGAYDGPRTADGIV 125
           +E  A  ++G   +A V+C  +   C K  VS     LK ++DGE    YD       +V
Sbjct: 717 FEEVAEEMRGKSTMAYVNCGEDKKFCKKLKVSPSSFELKHYKDGEFNKDYDRKLALKSMV 538

Query: 126 SHLKKQAG-------PAS---VPLRTEEEFKKFI-SDKDASVVGFF 160
           + L    G       P +   V + T++   K +  DK A++V F+
Sbjct: 537 NFLLXPTGDIPWDEDPTATDVVHIDTDDGLTKLLKKDKSAALVMFY 400
>21509
          Length = 754

 Score = 55.1 bits (131), Expect = 7e-08,   Method: Compositional matrix adjust.
 Identities = 40/117 (34%), Positives = 55/117 (47%), Gaps = 8/117 (6%)
 Frame = -3

Query: 30  LTDENFESRVSDTGSAGLMLVEFFAP--------WCGHCKRLAPEYEAAATRLKGIVPLA 81
           LT + F++ VS   S  +M     A         W G C           +R K +  +A
Sbjct: 713 LTKDTFDTFVSTHSSVLVMFTPHGADIVKNEASVWRGCCHH---------SRAK-LGAVA 564

Query: 82  KVDCTANTNTCNKYGVSGYPTLKIFRDGEEAGAYDGPRTADGIVSHLKKQAGPASVP 138
            VD T +    NKY V GYPTLK F+DG+ A  Y G R++D  VS +KK     ++P
Sbjct: 563 AVDATLDPELGNKYDVKGYPTLKYFKDGKLAFEYSGGRSSDAFVSFMKKAGAGPTLP 393

 Score = 52.0 bits (123), Expect = 6e-07,   Method: Compositional matrix adjust.
 Identities = 24/46 (52%), Positives = 29/46 (63%)
 Frame = -1

Query: 26  DVLELTDENFESRVSDTGSAGLMLVEFFAPWCGHCKRLAPEYEAAA 71
           DV  LTD  FES ++        LV F+APWCGHCK++ P Y AAA
Sbjct: 358 DVNHLTDATFESFIAANRRT---LVMFYAPWCGHCKKMKPAYMAAA 230

 Score = 42.4 bits (98), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 13/23 (56%), Positives = 18/23 (78%)
 Frame = -1

Query: 394 DKDVLIEFYAPWCGHCKNLEPKY 416
           ++  L+ FYAPWCGHCK ++P Y
Sbjct: 310 NRRTLVMFYAPWCGHCKKMKPAY 242

 Score = 34.3 bits (77), Expect = 0.11,   Method: Compositional matrix adjust.
 Identities = 31/116 (26%), Positives = 51/116 (43%), Gaps = 2/116 (1%)
 Frame = -3

Query: 373 SNEGPVKVVVAENFDDIVNEEDKDVLIEFYAPWCGHCKNLEPKYKELGEKLSKDPNIVIA 432
           S    V V+   +  DIV  E         + W G C +   K   LG          +A
Sbjct: 683 STHSSVLVMFTPHGADIVKNEA--------SVWRGCCHHSRAK---LG---------AVA 564

Query: 433 KMDATAN-DVPSPYEVKGFPTI-YFSPANKKLTPKKYEGGRELNDFISYLQREATN 486
            +DAT + ++ + Y+VKG+PT+ YF          +Y GGR  + F+S++++    
Sbjct: 563 AVDATLDPELGNKYDVKGYPTLKYFKDGKLAF---EYSGGRSSDAFVSFMKKAGAG 405
>36159
          Length = 369

 Score = 53.9 bits (128), Expect = 2e-07,   Method: Composition-based stats.
 Identities = 21/34 (61%), Positives = 25/34 (73%)
 Frame = -1

Query: 403 APWCGHCKNLEPKYKELGEKLSKDPNIVIAKMDA 436
           APWCGHCK L P + ELGEK     ++VIAKMD+
Sbjct: 102 APWCGHCKQLVPIWDELGEKFQDSDDVVIAKMDS 1

 Score = 34.7 bits (78), Expect = 0.097,   Method: Composition-based stats.
 Identities = 14/33 (42%), Positives = 21/33 (63%), Gaps = 2/33 (6%)
 Frame = -1

Query: 54  APWCGHCKRLAPEYEAAATRLKGI--VPLAKVD 84
           APWCGHCK+L P ++    + +    V +AK+D
Sbjct: 102 APWCGHCKQLVPIWDELGEKFQDSDDVVIAKMD 4
>07257
          Length = 1477

 Score = 45.8 bits (107), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 23/74 (31%), Positives = 34/74 (45%)
 Frame = -3

Query: 43   GSAGLMLVEFFAPWCGHCKRLAPEYEAAATRLKGIVPLAKVDCTANTNTCNKYGVSGYPT 102
             +A  +LV F+APWC  C   AP Y A A     +  LA VD    +N   ++G    P 
Sbjct: 1304 STADCVLVMFYAPWCHFCANTAPHYNALARAFPQLEVLA-VDTVHFSNLNARFGTVAVPN 1128

Query: 103  LKIFRDGEEAGAYD 116
            + +F     A  ++
Sbjct: 1127 IMLFHQSRSAVRFN 1086

 Score = 38.1 bits (87), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 17/46 (36%), Positives = 21/46 (45%), Gaps = 1/46 (2%)
 Frame = -3

Query: 391  NEEDKD-VLIEFYAPWCGHCKNLEPKYKELGEKLSKDPNIVIAKMD 435
            N    D VL+ FYAPWC  C N  P Y  L       P + +  +D
Sbjct: 1310 NHSTADCVLVMFYAPWCHFCANTAPHYNALARAF---PQLEVLAVD 1182
>15159
          Length = 1945

 Score = 44.7 bits (104), Expect = 8e-05,   Method: Compositional matrix adjust.
 Identities = 24/93 (25%), Positives = 45/93 (48%), Gaps = 1/93 (1%)
 Frame = +3

Query: 371 PESNEGPVKVVVAENFDDIVNEEDKDVLIEFYAPWCGHCKNLEPKYKELGEKLSKDPNIV 430
           P    G +K+  A++F+  + +  + V+++F+A WCG CK + PK  +  E+      + 
Sbjct: 63  PSKKMGVIKISSADDFEKAI-QGGQLVVVDFHATWCGPCKVIAPKLAKWSEEDRFKETVK 239

Query: 431 IAKMDA-TANDVPSPYEVKGFPTIYFSPANKKL 462
           I  +D     D+     +   PT +F    K+L
Sbjct: 240 IISVDVDELEDLAGEQGISAMPTFFFLEMEKRL 338

 Score = 41.2 bits (95), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 20/59 (33%), Positives = 30/59 (50%), Gaps = 2/59 (3%)
 Frame = +3

Query: 47  LMLVEFFAPWCGHCKRLAPEYEAAAT--RLKGIVPLAKVDCTANTNTCNKYGVSGYPTL 103
           L++V+F A WCG CK +AP+    +   R K  V +  VD     +   + G+S  PT 
Sbjct: 135 LVVVDFHATWCGPCKVIAPKLAKWSEEDRFKETVKIISVDVDELEDLAGEQGISAMPTF 311
>04779
          Length = 910

 Score = 44.3 bits (103), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 30/93 (32%), Positives = 42/93 (45%), Gaps = 9/93 (9%)
 Frame = +1

Query: 74  LKGIVPLAKVDCTANTNTCNKYGVSGYPTLKIF----RDGEEAGAYDGPRTADGIVS--- 126
           LKG V    +D TA+ N   +Y V GYPT+K F        +A  Y+G RTA  I++   
Sbjct: 4   LKGKVKFGALDATAHQNKAAEYNVRGYPTIKFFPANSNRASDAQEYNGGRTASDIIAWAS 183

Query: 127 --HLKKQAGPASVPLRTEEEFKKFISDKDASVV 157
             H +    P  + + +E  F      K   VV
Sbjct: 184 DKHTENVPPPELIEITSESTFDSACEGKPLCVV 282

 Score = 38.5 bits (88), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 21/60 (35%), Positives = 35/60 (58%), Gaps = 3/60 (5%)
 Frame = +1

Query: 429 IVIAKMDATAN-DVPSPYEVKGFPTIYFSPA--NKKLTPKKYEGGRELNDFISYLQREAT 485
           +    +DATA+ +  + Y V+G+PTI F PA  N+    ++Y GGR  +D I++   + T
Sbjct: 16  VKFGALDATAHQNKAAEYNVRGYPTIKFFPANSNRASDAQEYNGGRTASDIIAWASDKHT 195
>01000
          Length = 1541

 Score = 44.3 bits (103), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 19/52 (36%), Positives = 29/52 (55%), Gaps = 7/52 (13%)
 Frame = -1

Query: 83   VDCTANTNTCNKYGVSGYPTLKIFRDGEEAGAYDGPRT-------ADGIVSH 127
            VDCT  + TCN   + GYPTL +F++G+    + G R+        DG ++H
Sbjct: 1541 VDCTKQSETCNAQSIRGYPTLAVFQNGKRQEDFKGTRSLDDLQEFVDGFLTH 1386
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|20452466|ref|NP_032024.2| ferrochelatase [Mus
musculus]
         (422 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

08453                                                                 255   e-134
16393                                                                  29   4.4  
>08453
          Length = 1559

 Score =  255 bits (652), Expect(2) = e-134,   Method: Compositional matrix adjust.
 Identities = 118/190 (62%), Positives = 144/190 (75%)
 Frame = +3

Query: 70  ILMLNMGGPETLGEVXXXXXXXXXXXXXMTLPIQNKLAPFIAKRRTPKIQEQYRRIGGGS 129
           I+MLN+GGPE   +V             + LP Q+KLAP IAKRRTP I EQY++IGGGS
Sbjct: 3   IMMLNLGGPEKAEDVHDFLLRLFLDKDLIPLPAQSKLAPLIAKRRTPSIIEQYQKIGGGS 182

Query: 130 PIKMWTSKQGEGMVKLLDELSPATAPHKYYIGFRYVHPLTEEAIEEMERDGLERAIAFTQ 189
           PIK WT  QG+ MV +LD++SP TAPHK+YIGFRY HPLTE+ I++ME DG+ERA+AFTQ
Sbjct: 183 PIKRWTELQGQAMVDILDKISPQTAPHKFYIGFRYAHPLTEDTIQQMEEDGVERAVAFTQ 362

Query: 190 YPQYSCSTTGSSLNAIYRYYNEVGQKPTMKWSTIDRWPTHPLLIQCFADHILKELNHFPE 249
           YPQYSCSTTGSSLNAIYR+Y + G    + WS IDRWPTHP L++ F+++I  EL  FPE
Sbjct: 363 YPQYSCSTTGSSLNAIYRHYAKHGASNHIVWSVIDRWPTHPGLVKAFSNNIRDELARFPE 542

Query: 250 EKRSEVVILF 259
           E R +VVILF
Sbjct: 543 EDRDDVVILF 572

 Score =  239 bits (611), Expect(2) = e-134,   Method: Compositional matrix adjust.
 Identities = 109/164 (66%), Positives = 131/164 (79%)
 Frame = +2

Query: 258 LFSAHSLPMSVVNRGDPYPQEVGATVHKVMEKLGYPNPYRLVWQSKVGPVPWLGPQTDEA 317
             SAHSLP+ VVNRGDPYP EV ATV +VME+LG  + YRLVWQSKVGP+PWL PQTD+A
Sbjct: 566 FVSAHSLPLKVVNRGDPYPTEVSATVQRVMEELGNTHAYRLVWQSKVGPLPWLSPQTDDA 745

Query: 318 IKGLCERGRKNILLVPIAFTSDHIETLYELDIEYSQVLAQKCGAENIRRAESLNGNPLFS 377
           IKGL  RG+KN+LLVPIAFTSDHIETLYELD+EY+Q L  + G +NIRRA SLN NP+F 
Sbjct: 746 IKGLVTRGKKNLLLVPIAFTSDHIETLYELDLEYAQHLGAEVGVKNIRRAASLNDNPVFL 925

Query: 378 KALADLVHSHIQSNKLCSTQLSLNCPLCVNPVCRKTKSFFTSQQ 421
           +ALAD+V +H+ + ++CS QL+L CP+C N  C   K FF SQQ
Sbjct: 926 EALADIVKTHLDAGRVCSPQLTLRCPMCTNLTCGMAKEFFASQQ 1057
>16393
          Length = 2131

 Score = 28.9 bits (63), Expect = 4.4,   Method: Compositional matrix adjust.
 Identities = 38/133 (28%), Positives = 58/133 (43%), Gaps = 25/133 (18%)
 Frame = +3

Query: 313  QTDEAIKGLCER-GRKNILLVPIAFTSDHIETLYELDI----------EYSQVLAQKCGA 361
            + D    G C + G  N   V I +T + I + Y  DI          E  ++L Q+  A
Sbjct: 1077 ENDNENGGSCSQAGDDN---VDIMWTENTIFSNYTNDIFLEKDIXNRHEVDKIL-QETTA 1244

Query: 362  ENIRRAESLNGNPLFSKAL----ADLVHSHIQS----------NKLCSTQLSLNCPLCVN 407
             NI     +NGNPL S AL     D++HS IQ+          N++   Q   N  + V+
Sbjct: 1245 FNIN---DVNGNPLLSDALPVQNGDIIHS-IQTSISDNSDTSENEITHPQWQSNTQMNVD 1412

Query: 408  PVCRKTKSFFTSQ 420
             +  +  S F+S+
Sbjct: 1413 DILAEVNSHFSSR 1451
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|22165384|ref|NP_666228.1| tubulin, beta 2C [Mus
musculus]
         (445 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

16482                                                                 473   e-134
13181                                                                 464   e-131
04882                                                                 441   e-124
00276                                                                 274   7e-74
28905                                                                 260   2e-70
31457                                                                 250   1e-66
25015                                                                 246   1e-65
39157                                                                 233   4e-65
12457                                                                 209   2e-54
05902                                                                 155   4e-38
06360                                                                 137   1e-32
03702                                                                 120   9e-28
17215                                                                  81   8e-16
19746                                                                  40   0.002
29025                                                                  36   0.040
>16482
          Length = 837

 Score =  473 bits (1216), Expect = e-134,   Method: Compositional matrix adjust.
 Identities = 226/246 (91%), Positives = 227/246 (92%)
 Frame = +1

Query: 1   MREIVHLQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEATGGKYV 60
           MREIVH+QAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEATGGKYV
Sbjct: 100 MREIVHMQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEATGGKYV 279

Query: 61  PRAVLVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVV 120
           PRAVLVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVV
Sbjct: 280 PRAVLVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVV 459

Query: 121 RKEAESCDCLQGFQXXXXXXXXXXXXXXXXXXXKIREEYPDRIMNTFSVVPSPKVSDTVV 180
           RKEAESCDCLQGFQ                   KIREEYPDRIMNTFSVVPSPKVSDTVV
Sbjct: 460 RKEAESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVVPSPKVSDTVV 639

Query: 181 EPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCL 240
           EPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCL
Sbjct: 640 EPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCL 819

Query: 241 RFPGQL 246
           RFPGQL
Sbjct: 820 RFPGQL 837
>13181
          Length = 1092

 Score =  464 bits (1195), Expect = e-131,   Method: Compositional matrix adjust.
 Identities = 218/220 (99%), Positives = 220/220 (100%)
 Frame = -3

Query: 208  YDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFM 267
            YDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFM
Sbjct: 1090 YDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFM 911

Query: 268  PGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAVFRGRMSMKEVD 327
            PGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAA+FRGRMSMKEVD
Sbjct: 910  PGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAMFRGRMSMKEVD 731

Query: 328  EQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTA 387
            EQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATF+GNSTAIQELFKRISEQFTA
Sbjct: 730  EQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFVGNSTAIQELFKRISEQFTA 551

Query: 388  MFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQD 427
            MFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQD
Sbjct: 550  MFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQD 431
>04882
          Length = 1136

 Score =  441 bits (1134), Expect = e-124,   Method: Compositional matrix adjust.
 Identities = 207/209 (99%), Positives = 209/209 (100%)
 Frame = +2

Query: 219 TPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGS 278
           TPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGS
Sbjct: 320 TPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGS 499

Query: 279 QQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAVFRGRMSMKEVDEQMLNVQNKNS 338
           QQYRALTVPELTQQMFD+KNMMAACDPRHGRYLTVAA+FRGRMSMKEVDEQMLNVQNKNS
Sbjct: 500 QQYRALTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNS 679

Query: 339 SYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWY 398
           SYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWY
Sbjct: 680 SYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWY 859

Query: 399 TGEGMDEMEFTEAESNMNDLVSEYQQYQD 427
           TGEGMDEMEFTEAESNMNDLVSEYQQYQD
Sbjct: 860 TGEGMDEMEFTEAESNMNDLVSEYQQYQD 946
>00276
          Length = 1330

 Score =  274 bits (700), Expect = 7e-74,   Method: Compositional matrix adjust.
 Identities = 131/355 (36%), Positives = 203/355 (57%), Gaps = 8/355 (2%)
 Frame = -3

Query: 78   SGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEAESCDCLQGFQXXX 137
            +G + Q+  P+  V G+  A NN+A+GHYT G ELVD VLD +RK A+ C  LQGF    
Sbjct: 1328 TGTYRQL-SPEQLVTGKEDAANNYARGHYTIGKELVDLVLDRIRKLADQCTGLQGFLIFH 1152

Query: 138  XXXXXXXXXXXXXXXXKIREEYPDRIMNTFSVVPSPKVSDTVVEPYNATLSVHQLVENTD 197
                            ++  +Y  +    F + P+P+VS  VVEPYN+ L+ H  +E++D
Sbjct: 1151 SFGGGTGSGFTSLXMERLSVDYGKKSKLEFXIYPAPQVSTAVVEPYNSILTTHTTLEHSD 972

Query: 198  ETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNM 257
              + +DNEA+YDIC R L +  PTY +LN L+   +S +T  LRF G LN DL +   N+
Sbjct: 971  CAFMVDNEAIYDICRRNLDIERPTYTNLNRLIXQIVSSITASLRFDGALNVDLTEFQTNL 792

Query: 258  VPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAVF 317
            VP+PR+HF +  +AP+ S     +  L V E+T   F+  N +  CDPRHG+Y+    ++
Sbjct: 791  VPYPRIHFPLATYAPVISAEKAYHEQLXVAEITNACFEPANQLVKCDPRHGKYMACCMLY 612

Query: 318  RGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPR--------GLKMSATFIG 369
            RG +  K+V+  +  ++ K +  FV+W P   K  +   PP          ++ +   + 
Sbjct: 611  RGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLS 432

Query: 370  NSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQ 424
            N+TAI E + R+  +F  M+ ++AF+HWY GEGM+E EF+EA  ++  L  +Y++
Sbjct: 431  NTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEE 267
>28905
          Length = 425

 Score =  260 bits (664), Expect(2) = 2e-70,   Method: Compositional matrix adjust.
 Identities = 124/129 (96%), Positives = 126/129 (97%), Gaps = 1/129 (0%)
 Frame = -1

Query: 253 LAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLT 312
           +AVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLT
Sbjct: 389 VAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLT 210

Query: 313 VAAVFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNST 372
           VAA+FRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMS TFIGNST
Sbjct: 209 VAAMFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSGTFIGNST 30

Query: 373 AIQ-ELFKR 380
           AIQ  LFKR
Sbjct: 29  AIQGRLFKR 3

 Score = 23.9 bits (50), Expect(2) = 2e-70,   Method: Composition-based stats.
 Identities = 9/9 (100%), Positives = 9/9 (100%)
 Frame = -2

Query: 242 FPGQLNADL 250
           FPGQLNADL
Sbjct: 424 FPGQLNADL 398
>31457
          Length = 1530

 Score =  250 bits (638), Expect = 1e-66,   Method: Compositional matrix adjust.
 Identities = 116/119 (97%), Positives = 119/119 (100%)
 Frame = +3

Query: 309 RYLTVAAVFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFI 368
           +YLTVAA+FRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMS+TFI
Sbjct: 234 KYLTVAAMFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSSTFI 413

Query: 369 GNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQD 427
           GNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQD
Sbjct: 414 GNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQD 590
>25015
          Length = 458

 Score =  246 bits (629), Expect = 1e-65,   Method: Compositional matrix adjust.
 Identities = 115/115 (100%), Positives = 115/115 (100%)
 Frame = -3

Query: 20  FWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEATGGKYVPRAVLVDLEPGTMDSVRSG 79
           FWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEATGGKYVPRAVLVDLEPGTMDSVRSG
Sbjct: 363 FWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEATGGKYVPRAVLVDLEPGTMDSVRSG 184

Query: 80  PFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEAESCDCLQGFQ 134
           PFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEAESCDCLQGFQ
Sbjct: 183 PFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEAESCDCLQGFQ 19
>39157
          Length = 488

 Score =  233 bits (593), Expect(2) = 4e-65,   Method: Compositional matrix adjust.
 Identities = 115/127 (90%), Positives = 118/127 (92%), Gaps = 3/127 (2%)
 Frame = -1

Query: 1   MREIVHLQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEATGGKYV 60
           MREIVHLQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEATGGKYV
Sbjct: 443 MREIVHLQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEATGGKYV 264

Query: 61  PRAVLVDLEPGTMDSVRSG-PFG-QIFRPDNFVFGQSGAGNNWAKGHYTE-GAELVDSVL 117
           PRAVLVDLEPGTMDSVRSG PFG +IFRPDNFVFGQSGAGNNW +   T+ GAELVDSVL
Sbjct: 263 PRAVLVDLEPGTMDSVRSGSPFGPKIFRPDNFVFGQSGAGNNWGQKDTTQRGAELVDSVL 84

Query: 118 DVVRKEA 124
           DVVRK  
Sbjct: 83  DVVRKRG 63

 Score = 33.9 bits (76), Expect(2) = 4e-65,   Method: Compositional matrix adjust.
 Identities = 13/13 (100%), Positives = 13/13 (100%)
 Frame = -2

Query: 122 KEAESCDCLQGFQ 134
           KEAESCDCLQGFQ
Sbjct: 70  KEAESCDCLQGFQ 32
>12457
          Length = 781

 Score =  209 bits (532), Expect = 2e-54,   Method: Compositional matrix adjust.
 Identities = 99/239 (41%), Positives = 141/239 (58%)
 Frame = -1

Query: 65  LVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEA 124
           LVDLEP  +D VR+G + Q+F P+  V G+  A NN+A+GHYT G E+VD VLD +RK A
Sbjct: 718 LVDLEPTVVDEVRTGTYRQLFHPEQLVTGKEDAANNYARGHYTIGKEIVDLVLDRIRKLA 539

Query: 125 ESCDCLQGFQXXXXXXXXXXXXXXXXXXXKIREEYPDRIMNTFSVVPSPKVSDTVVEPYN 184
           + C  LQGF                    ++  +Y  +    F++ P+P+VS  VVEPYN
Sbjct: 538 DQCTGLQGFLIFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFAIYPAPQVSTAVVEPYN 359

Query: 185 ATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPG 244
           + L+ H  +E++D  + +DNEA+YDIC R L +  PTY +LN L+   +S +T  LRF G
Sbjct: 358 SILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLRFDG 179

Query: 245 QLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAAC 303
            LN DL +   N+VP+PR+HF +  +AP+ S     +  LTV E+T   F+  N M  C
Sbjct: 178 ALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLTVAEITNACFEPANQMVKC 2
>05902
          Length = 1127

 Score =  155 bits (391), Expect = 4e-38,   Method: Compositional matrix adjust.
 Identities = 91/282 (32%), Positives = 158/282 (56%), Gaps = 12/282 (4%)
 Frame = +2

Query: 154 KIREEYPDRIMNTFSVVPS-PKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICF 212
           K+ + +P +++ T+SV P+  ++SD VV+PYN+ L++ +L +N D    +DN AL  I  
Sbjct: 74  KLNDRFPKKLIQTYSVFPNVDEISDVVVQPYNSLLTLKRLTQNADCVVVLDNTALNRIAA 253

Query: 213 RTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAP 272
             L + TPT+  +N LVS  MS  TT LR+PG +N DL  L  +++P PRLHF M G+ P
Sbjct: 254 DRLHIDTPTFAQVNQLVSTVMSTSTTTLRYPGYMNNDLIGLIASLIPTPRLHFLMTGYTP 433

Query: 273 LTSRGS-QQYRALTVPELTQQMFDAKNMMAACDPRHGR----YLTVAAVFRGRMSMKEVD 327
           LT+       R  TV ++ +++   KNMM +  P H +    Y+++  + +G +   +V 
Sbjct: 434 LTTDSQVANVRKTTVLDVMRRLLQPKNMMVST-PVHRQANHCYISILNIIQGEVDPTQVH 610

Query: 328 EQMLNVQNKNSSYFVEWIPNNVKTAVCDIPP---RGLKMSATFIGNSTAIQELFKRISEQ 384
           + +  ++ +  + F+ W P +++ A+    P      ++S   + N T+I  LF+RI  Q
Sbjct: 611 KSLQRIRERKLAQFIPWGPASIQVALSRKSPYVQTAHRVSGLMLANHTSISHLFERILRQ 790

Query: 385 FTAMFRRKAFLHWYTGEGM--DEM-EFTEAESNMNDLVSEYQ 423
           +  + +R+AF+  +  E +  D + EF  +   +  LV EYQ
Sbjct: 791 YDKLRKREAFMDQFKKEAIFKDNLDEFDNSREALQLLVDEYQ 916
>06360
          Length = 1896

 Score =  137 bits (344), Expect = 1e-32,   Method: Compositional matrix adjust.
 Identities = 70/179 (39%), Positives = 99/179 (55%), Gaps = 2/179 (1%)
 Frame = -1

Query: 1    MREIVHLQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQL--ERINVYYNEATGGK 58
            MRE + +  GQ G Q+G   WE+   EHGI P G    D  +    +  N +++E   GK
Sbjct: 1710 MRECISVHVGQAGVQMGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGK 1531

Query: 59   YVPRAVLVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLD 118
            +VPRAV VDLEP  +D VR+G + Q+F P+  V G+  A NN+A+GHYT G E+VD VLD
Sbjct: 1530 HVPRAVFVDLEPTVVDEVRTGTYRQLFHPEQLVTGKEDAANNYARGHYTIGKEIVDLVLD 1351

Query: 119  VVRKEAESCDCLQGFQXXXXXXXXXXXXXXXXXXXKIREEYPDRIMNTFSVVPSPKVSD 177
             +RK A+ C  LQGF                    ++  +Y  +    F++ P+P+VSD
Sbjct: 1350 RIRKLADQCTGLQGFLIFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFAIYPAPQVSD 1174
>03702
          Length = 1932

 Score =  120 bits (302), Expect = 9e-28,   Method: Compositional matrix adjust.
 Identities = 59/140 (42%), Positives = 83/140 (59%), Gaps = 1/140 (0%)
 Frame = +1

Query: 167  FSVVPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLN 226
            F++ P+P+VS  VVEPYN+ L+ H  +E++D  + +DNEA+YDIC R L +  P Y +LN
Sbjct: 1501 FAIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPXYTNLN 1680

Query: 227  HLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPG-FAPLTSRGSQQYRALT 285
             L+   +S +T  LRF G LN DL +   N+VP P  H   PG   P+ S     +  LT
Sbjct: 1681 RLIGQIVSSITASLRFDGALNVDLTEFQTNLVPTP--HPLPPGHLCPVISAEKAYHEQLT 1854

Query: 286  VPELTQQMFDAKNMMAACDP 305
            V E+T   F+  N +  CDP
Sbjct: 1855 VAEVTNACFEPANQLVKCDP 1914
>17215
          Length = 632

 Score = 81.3 bits (199), Expect = 8e-16,   Method: Compositional matrix adjust.
 Identities = 36/117 (30%), Positives = 66/117 (56%), Gaps = 8/117 (6%)
 Frame = +3

Query: 316 VFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPR--------GLKMSATF 367
           ++RG +  K+V+  +  ++ K +  FV+W P   K  +   PP          ++ +   
Sbjct: 6   LYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCM 185

Query: 368 IGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQ 424
           + N+TAI E + R+  +F  M+ ++AF+HWY GEGM+E EF+EA  ++  L  +Y++
Sbjct: 186 LSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEE 356
>19746
          Length = 446

 Score = 40.0 bits (92), Expect = 0.002,   Method: Composition-based stats.
 Identities = 24/88 (27%), Positives = 40/88 (45%), Gaps = 2/88 (2%)
 Frame = +1

Query: 337 NSSYFVEWIPNNVKTAVCDIPPR--GLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAF 394
           + S F  W   N+   V + P      + SAT + NS +       I E+   MF  +A+
Sbjct: 49  DPSLFTLWTCPNMAFNVSNQPRAFCAYEKSATLVSNSRSSTRPLDDIMEKAWKMFASRAY 228

Query: 395 LHWYTGEGMDEMEFTEAESNMNDLVSEY 422
           +H Y   G+ E +F +A   +  +V+ Y
Sbjct: 229 IHQYVKRGLSEEDFLDAFVTLEQVVASY 312
>29025
          Length = 395

 Score = 35.8 bits (81), Expect = 0.040,   Method: Compositional matrix adjust.
 Identities = 16/16 (100%), Positives = 16/16 (100%)
 Frame = -3

Query: 412 ESNMNDLVSEYQQYQD 427
           ESNMNDLVSEYQQYQD
Sbjct: 354 ESNMNDLVSEYQQYQD 307
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|21746161|ref|NP_076205.1| tubulin, beta [Mus
musculus]
         (445 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

13181                                                                 469   e-133
16482                                                                 467   e-132
04882                                                                 449   e-126
00276                                                                 273   7e-74
28905                                                                 259   3e-70
31457                                                                 255   2e-68
25015                                                                 242   3e-64
39157                                                                 228   2e-63
12457                                                                 208   3e-54
05902                                                                 156   2e-38
06360                                                                 134   6e-32
03702                                                                 121   7e-28
17215                                                                  82   6e-16
29025                                                                  42   7e-04
19746                                                                  39   0.005
>13181
          Length = 1092

 Score =  469 bits (1208), Expect = e-133,   Method: Compositional matrix adjust.
 Identities = 220/223 (98%), Positives = 223/223 (100%)
 Frame = -3

Query: 208  YDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFM 267
            YDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFM
Sbjct: 1090 YDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFM 911

Query: 268  PGFAPLTSRGSQQYRALTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKEVD 327
            PGFAPLTSRGSQQYRALTVPELTQQMFD+KNMMAACDPRHGRYLTVAA+FRGRMSMKEVD
Sbjct: 910  PGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAMFRGRMSMKEVD 731

Query: 328  EQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTA 387
            EQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATF+GNSTAIQELFKRISEQFTA
Sbjct: 730  EQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFVGNSTAIQELFKRISEQFTA 551

Query: 388  MFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATA 430
            MFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATA
Sbjct: 550  MFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATA 422
>16482
          Length = 837

 Score =  467 bits (1201), Expect = e-132,   Method: Compositional matrix adjust.
 Identities = 221/246 (89%), Positives = 226/246 (91%)
 Frame = +1

Query: 1   MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEATGNKYV 60
           MREIVH+QAGQCGNQIGAKFWEVISDEHGIDPTG+YHGDSDLQLERINVYYNEATG KYV
Sbjct: 100 MREIVHMQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEATGGKYV 279

Query: 61  PRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVV 120
           PRA+LVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVV
Sbjct: 280 PRAVLVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVV 459

Query: 121 RKESESCDCLQGFQXXXXXXXXXXXXXXXXXXXKIREEYPDRIMNTFSVMPSPKVSDTVV 180
           RKE+ESCDCLQGFQ                   KIREEYPDRIMNTFSV+PSPKVSDTVV
Sbjct: 460 RKEAESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVVPSPKVSDTVV 639

Query: 181 EPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCL 240
           EPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCL
Sbjct: 640 EPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCL 819

Query: 241 RFPGQL 246
           RFPGQL
Sbjct: 820 RFPGQL 837
>04882
          Length = 1136

 Score =  449 bits (1154), Expect = e-126,   Method: Compositional matrix adjust.
 Identities = 212/212 (100%), Positives = 212/212 (100%)
 Frame = +2

Query: 219 TPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGS 278
           TPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGS
Sbjct: 320 TPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGS 499

Query: 279 QQYRALTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNS 338
           QQYRALTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNS
Sbjct: 500 QQYRALTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNS 679

Query: 339 SYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWY 398
           SYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWY
Sbjct: 680 SYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWY 859

Query: 399 TGEGMDEMEFTEAESNMNDLVSEYQQYQDATA 430
           TGEGMDEMEFTEAESNMNDLVSEYQQYQDATA
Sbjct: 860 TGEGMDEMEFTEAESNMNDLVSEYQQYQDATA 955
>00276
          Length = 1330

 Score =  273 bits (699), Expect = 7e-74,   Method: Compositional matrix adjust.
 Identities = 130/355 (36%), Positives = 203/355 (57%), Gaps = 8/355 (2%)
 Frame = -3

Query: 78   SGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQXXX 137
            +G + Q+  P+  V G+  A NN+A+GHYT G ELVD VLD +RK ++ C  LQGF    
Sbjct: 1328 TGTYRQL-SPEQLVTGKEDAANNYARGHYTIGKELVDLVLDRIRKLADQCTGLQGFLIFH 1152

Query: 138  XXXXXXXXXXXXXXXXKIREEYPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVENTD 197
                            ++  +Y  +    F + P+P+VS  VVEPYN+ L+ H  +E++D
Sbjct: 1151 SFGGGTGSGFTSLXMERLSVDYGKKSKLEFXIYPAPQVSTAVVEPYNSILTTHTTLEHSD 972

Query: 198  ETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNM 257
              + +DNEA+YDIC R L +  PTY +LN L+   +S +T  LRF G LN DL +   N+
Sbjct: 971  CAFMVDNEAIYDICRRNLDIERPTYTNLNRLIXQIVSSITASLRFDGALNVDLTEFQTNL 792

Query: 258  VPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIF 317
            VP+PR+HF +  +AP+ S     +  L V E+T   F+  N +  CDPRHG+Y+    ++
Sbjct: 791  VPYPRIHFPLATYAPVISAEKAYHEQLXVAEITNACFEPANQLVKCDPRHGKYMACCMLY 612

Query: 318  RGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPR--------GLKMSATFIG 369
            RG +  K+V+  +  ++ K +  FV+W P   K  +   PP          ++ +   + 
Sbjct: 611  RGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLS 432

Query: 370  NSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQ 424
            N+TAI E + R+  +F  M+ ++AF+HWY GEGM+E EF+EA  ++  L  +Y++
Sbjct: 431  NTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEE 267
>28905
          Length = 425

 Score =  259 bits (663), Expect(2) = 3e-70,   Method: Compositional matrix adjust.
 Identities = 123/129 (95%), Positives = 126/129 (97%), Gaps = 1/129 (0%)
 Frame = -1

Query: 253 LAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDSKNMMAACDPRHGRYLT 312
           +AVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFD+KNMMAACDPRHGRYLT
Sbjct: 389 VAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLT 210

Query: 313 VAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNST 372
           VAA+FRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMS TFIGNST
Sbjct: 209 VAAMFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSGTFIGNST 30

Query: 373 AIQ-ELFKR 380
           AIQ  LFKR
Sbjct: 29  AIQGRLFKR 3

 Score = 23.9 bits (50), Expect(2) = 3e-70,   Method: Composition-based stats.
 Identities = 9/9 (100%), Positives = 9/9 (100%)
 Frame = -2

Query: 242 FPGQLNADL 250
           FPGQLNADL
Sbjct: 424 FPGQLNADL 398
>31457
          Length = 1530

 Score =  255 bits (652), Expect = 2e-68,   Method: Compositional matrix adjust.
 Identities = 119/122 (97%), Positives = 122/122 (100%)
 Frame = +3

Query: 309 RYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFI 368
           +YLTVAA+FRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMS+TFI
Sbjct: 234 KYLTVAAMFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSSTFI 413

Query: 369 GNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDA 428
           GNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDA
Sbjct: 414 GNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDA 593

Query: 429 TA 430
           TA
Sbjct: 594 TA 599
>25015
          Length = 458

 Score =  242 bits (617), Expect = 3e-64,   Method: Compositional matrix adjust.
 Identities = 111/115 (96%), Positives = 114/115 (99%)
 Frame = -3

Query: 20  FWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEATGNKYVPRAILVDLEPGTMDSVRSG 79
           FWEVISDEHGIDPTG+YHGDSDLQLERINVYYNEATG KYVPRA+LVDLEPGTMDSVRSG
Sbjct: 363 FWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEATGGKYVPRAVLVDLEPGTMDSVRSG 184

Query: 80  PFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQ 134
           PFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKE+ESCDCLQGFQ
Sbjct: 183 PFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEAESCDCLQGFQ 19
>39157
          Length = 488

 Score =  228 bits (581), Expect(2) = 2e-63,   Method: Compositional matrix adjust.
 Identities = 111/127 (87%), Positives = 117/127 (92%), Gaps = 3/127 (2%)
 Frame = -1

Query: 1   MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEATGNKYV 60
           MREIVH+QAGQCGNQIGAKFWEVISDEHGIDPTG+YHGDSDLQLERINVYYNEATG KYV
Sbjct: 443 MREIVHLQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEATGGKYV 264

Query: 61  PRAILVDLEPGTMDSVRSG-PFG-QIFRPDNFVFGQSGAGNNWAKGHYTE-GAELVDSVL 117
           PRA+LVDLEPGTMDSVRSG PFG +IFRPDNFVFGQSGAGNNW +   T+ GAELVDSVL
Sbjct: 263 PRAVLVDLEPGTMDSVRSGSPFGPKIFRPDNFVFGQSGAGNNWGQKDTTQRGAELVDSVL 84

Query: 118 DVVRKES 124
           DVVRK  
Sbjct: 83  DVVRKRG 63

 Score = 32.7 bits (73), Expect(2) = 2e-63,   Method: Compositional matrix adjust.
 Identities = 12/13 (92%), Positives = 13/13 (100%)
 Frame = -2

Query: 122 KESESCDCLQGFQ 134
           KE+ESCDCLQGFQ
Sbjct: 70  KEAESCDCLQGFQ 32
>12457
          Length = 781

 Score =  208 bits (530), Expect = 3e-54,   Method: Compositional matrix adjust.
 Identities = 98/239 (41%), Positives = 141/239 (58%)
 Frame = -1

Query: 65  LVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKES 124
           LVDLEP  +D VR+G + Q+F P+  V G+  A NN+A+GHYT G E+VD VLD +RK +
Sbjct: 718 LVDLEPTVVDEVRTGTYRQLFHPEQLVTGKEDAANNYARGHYTIGKEIVDLVLDRIRKLA 539

Query: 125 ESCDCLQGFQXXXXXXXXXXXXXXXXXXXKIREEYPDRIMNTFSVMPSPKVSDTVVEPYN 184
           + C  LQGF                    ++  +Y  +    F++ P+P+VS  VVEPYN
Sbjct: 538 DQCTGLQGFLIFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFAIYPAPQVSTAVVEPYN 359

Query: 185 ATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPG 244
           + L+ H  +E++D  + +DNEA+YDIC R L +  PTY +LN L+   +S +T  LRF G
Sbjct: 358 SILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLRFDG 179

Query: 245 QLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDSKNMMAAC 303
            LN DL +   N+VP+PR+HF +  +AP+ S     +  LTV E+T   F+  N M  C
Sbjct: 178 ALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLTVAEITNACFEPANQMVKC 2
>05902
          Length = 1127

 Score =  156 bits (394), Expect = 2e-38,   Method: Compositional matrix adjust.
 Identities = 92/282 (32%), Positives = 158/282 (56%), Gaps = 12/282 (4%)
 Frame = +2

Query: 154 KIREEYPDRIMNTFSVMPS-PKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICF 212
           K+ + +P +++ T+SV P+  ++SD VV+PYN+ L++ +L +N D    +DN AL  I  
Sbjct: 74  KLNDRFPKKLIQTYSVFPNVDEISDVVVQPYNSLLTLKRLTQNADCVVVLDNTALNRIAA 253

Query: 213 RTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAP 272
             L + TPT+  +N LVS  MS  TT LR+PG +N DL  L  +++P PRLHF M G+ P
Sbjct: 254 DRLHIDTPTFAQVNQLVSTVMSTSTTTLRYPGYMNNDLIGLIASLIPTPRLHFLMTGYTP 433

Query: 273 LTSRGS-QQYRALTVPELTQQMFDSKNMMAACDPRHGR----YLTVAAIFRGRMSMKEVD 327
           LT+       R  TV ++ +++   KNMM +  P H +    Y+++  I +G +   +V 
Sbjct: 434 LTTDSQVANVRKTTVLDVMRRLLQPKNMMVST-PVHRQANHCYISILNIIQGEVDPTQVH 610

Query: 328 EQMLNVQNKNSSYFVEWIPNNVKTAVCDIPP---RGLKMSATFIGNSTAIQELFKRISEQ 384
           + +  ++ +  + F+ W P +++ A+    P      ++S   + N T+I  LF+RI  Q
Sbjct: 611 KSLQRIRERKLAQFIPWGPASIQVALSRKSPYVQTAHRVSGLMLANHTSISHLFERILRQ 790

Query: 385 FTAMFRRKAFLHWYTGEGM--DEM-EFTEAESNMNDLVSEYQ 423
           +  + +R+AF+  +  E +  D + EF  +   +  LV EYQ
Sbjct: 791 YDKLRKREAFMDQFKKEAIFKDNLDEFDNSREALQLLVDEYQ 916
>06360
          Length = 1896

 Score =  134 bits (338), Expect = 6e-32,   Method: Compositional matrix adjust.
 Identities = 67/179 (37%), Positives = 98/179 (54%), Gaps = 2/179 (1%)
 Frame = -1

Query: 1    MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQL--ERINVYYNEATGNK 58
            MRE + +  GQ G Q+G   WE+   EHGI P G    D  +    +  N +++E    K
Sbjct: 1710 MRECISVHVGQAGVQMGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGK 1531

Query: 59   YVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLD 118
            +VPRA+ VDLEP  +D VR+G + Q+F P+  V G+  A NN+A+GHYT G E+VD VLD
Sbjct: 1530 HVPRAVFVDLEPTVVDEVRTGTYRQLFHPEQLVTGKEDAANNYARGHYTIGKEIVDLVLD 1351

Query: 119  VVRKESESCDCLQGFQXXXXXXXXXXXXXXXXXXXKIREEYPDRIMNTFSVMPSPKVSD 177
             +RK ++ C  LQGF                    ++  +Y  +    F++ P+P+VSD
Sbjct: 1350 RIRKLADQCTGLQGFLIFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFAIYPAPQVSD 1174
>03702
          Length = 1932

 Score =  121 bits (303), Expect = 7e-28,   Method: Compositional matrix adjust.
 Identities = 59/140 (42%), Positives = 83/140 (59%), Gaps = 1/140 (0%)
 Frame = +1

Query: 167  FSVMPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLN 226
            F++ P+P+VS  VVEPYN+ L+ H  +E++D  + +DNEA+YDIC R L +  P Y +LN
Sbjct: 1501 FAIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPXYTNLN 1680

Query: 227  HLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPG-FAPLTSRGSQQYRALT 285
             L+   +S +T  LRF G LN DL +   N+VP P  H   PG   P+ S     +  LT
Sbjct: 1681 RLIGQIVSSITASLRFDGALNVDLTEFQTNLVPTP--HPLPPGHLCPVISAEKAYHEQLT 1854

Query: 286  VPELTQQMFDSKNMMAACDP 305
            V E+T   F+  N +  CDP
Sbjct: 1855 VAEVTNACFEPANQLVKCDP 1914
>17215
          Length = 632

 Score = 81.6 bits (200), Expect = 6e-16,   Method: Compositional matrix adjust.
 Identities = 36/117 (30%), Positives = 66/117 (56%), Gaps = 8/117 (6%)
 Frame = +3

Query: 316 IFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPR--------GLKMSATF 367
           ++RG +  K+V+  +  ++ K +  FV+W P   K  +   PP          ++ +   
Sbjct: 6   LYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCM 185

Query: 368 IGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQ 424
           + N+TAI E + R+  +F  M+ ++AF+HWY GEGM+E EF+EA  ++  L  +Y++
Sbjct: 186 LSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEE 356
>29025
          Length = 395

 Score = 41.6 bits (96), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 19/19 (100%), Positives = 19/19 (100%)
 Frame = -3

Query: 412 ESNMNDLVSEYQQYQDATA 430
           ESNMNDLVSEYQQYQDATA
Sbjct: 354 ESNMNDLVSEYQQYQDATA 298
>19746
          Length = 446

 Score = 38.9 bits (89), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 24/86 (27%), Positives = 39/86 (45%), Gaps = 2/86 (2%)
 Frame = +1

Query: 339 SYFVEWIPNNVKTAVCDIPPR--GLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLH 396
           S F  W   N+   V + P      + SAT + NS +       I E+   MF  +A++H
Sbjct: 55  SLFTLWTCPNMAFNVSNQPRAFCAYEKSATLVSNSRSSTRPLDDIMEKAWKMFASRAYIH 234

Query: 397 WYTGEGMDEMEFTEAESNMNDLVSEY 422
            Y   G+ E +F +A   +  +V+ Y
Sbjct: 235 QYVKRGLSEEDFLDAFVTLEQVVASY 312
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|33859488|ref|NP_033476.1| tubulin, beta 2 [Mus
musculus]
         (445 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

13181                                                                 470   e-133
16482                                                                 462   e-130
04882                                                                 449   e-126
00276                                                                 274   6e-74
28905                                                                 259   3e-70
31457                                                                 255   2e-68
25015                                                                 240   8e-64
39157                                                                 226   7e-63
12457                                                                 209   3e-54
05902                                                                 155   3e-38
06360                                                                 135   3e-32
03702                                                                 121   6e-28
17215                                                                  82   6e-16
29025                                                                  42   7e-04
19746                                                                  39   0.005
>13181
          Length = 1092

 Score =  470 bits (1209), Expect = e-133,   Method: Compositional matrix adjust.
 Identities = 220/223 (98%), Positives = 223/223 (100%)
 Frame = -3

Query: 208  YDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFM 267
            YDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFM
Sbjct: 1090 YDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFM 911

Query: 268  PGFAPLTSRGSQQYRALTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKEVD 327
            PGFAPLTSRGSQQYRALTVPELTQQMFD+KNMMAACDPRHGRYLTVAA+FRGRMSMKEVD
Sbjct: 910  PGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAMFRGRMSMKEVD 731

Query: 328  EQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTA 387
            EQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATF+GNSTAIQELFKRISEQFTA
Sbjct: 730  EQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFVGNSTAIQELFKRISEQFTA 551

Query: 388  MFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATA 430
            MFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATA
Sbjct: 550  MFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATA 422
>16482
          Length = 837

 Score =  462 bits (1188), Expect = e-130,   Method: Compositional matrix adjust.
 Identities = 219/246 (89%), Positives = 224/246 (91%)
 Frame = +1

Query: 1   MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEAAGNKYV 60
           MREIVH+QAGQCGNQIGAKFWEVISDEHGIDPTG+YHGDSDLQLERINVYYNEA G KYV
Sbjct: 100 MREIVHMQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEATGGKYV 279

Query: 61  PRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVV 120
           PRA+LVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVV
Sbjct: 280 PRAVLVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVV 459

Query: 121 RKESESCDCLQGFQXXXXXXXXXXXXXXXXXXXKIREEYPDRIMNTFSVMPSPKVSDTVV 180
           RKE+ESCDCLQGFQ                   KIREEYPDRIMNTFSV+PSPKVSDTVV
Sbjct: 460 RKEAESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVVPSPKVSDTVV 639

Query: 181 EPYNATLSVHQLVENTDETYSIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCL 240
           EPYNATLSVHQLVENTDETY IDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCL
Sbjct: 640 EPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCL 819

Query: 241 RFPGQL 246
           RFPGQL
Sbjct: 820 RFPGQL 837
>04882
          Length = 1136

 Score =  449 bits (1154), Expect = e-126,   Method: Compositional matrix adjust.
 Identities = 212/212 (100%), Positives = 212/212 (100%)
 Frame = +2

Query: 219 TPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGS 278
           TPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGS
Sbjct: 320 TPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGS 499

Query: 279 QQYRALTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNS 338
           QQYRALTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNS
Sbjct: 500 QQYRALTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNS 679

Query: 339 SYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWY 398
           SYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWY
Sbjct: 680 SYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWY 859

Query: 399 TGEGMDEMEFTEAESNMNDLVSEYQQYQDATA 430
           TGEGMDEMEFTEAESNMNDLVSEYQQYQDATA
Sbjct: 860 TGEGMDEMEFTEAESNMNDLVSEYQQYQDATA 955
>00276
          Length = 1330

 Score =  274 bits (700), Expect = 6e-74,   Method: Compositional matrix adjust.
 Identities = 130/355 (36%), Positives = 203/355 (57%), Gaps = 8/355 (2%)
 Frame = -3

Query: 78   SGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQXXX 137
            +G + Q+  P+  V G+  A NN+A+GHYT G ELVD VLD +RK ++ C  LQGF    
Sbjct: 1328 TGTYRQL-SPEQLVTGKEDAANNYARGHYTIGKELVDLVLDRIRKLADQCTGLQGFLIFH 1152

Query: 138  XXXXXXXXXXXXXXXXKIREEYPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVENTD 197
                            ++  +Y  +    F + P+P+VS  VVEPYN+ L+ H  +E++D
Sbjct: 1151 SFGGGTGSGFTSLXMERLSVDYGKKSKLEFXIYPAPQVSTAVVEPYNSILTTHTTLEHSD 972

Query: 198  ETYSIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNM 257
              + +DNEA+YDIC R L +  PTY +LN L+   +S +T  LRF G LN DL +   N+
Sbjct: 971  CAFMVDNEAIYDICRRNLDIERPTYTNLNRLIXQIVSSITASLRFDGALNVDLTEFQTNL 792

Query: 258  VPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIF 317
            VP+PR+HF +  +AP+ S     +  L V E+T   F+  N +  CDPRHG+Y+    ++
Sbjct: 791  VPYPRIHFPLATYAPVISAEKAYHEQLXVAEITNACFEPANQLVKCDPRHGKYMACCMLY 612

Query: 318  RGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPR--------GLKMSATFIG 369
            RG +  K+V+  +  ++ K +  FV+W P   K  +   PP          ++ +   + 
Sbjct: 611  RGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLS 432

Query: 370  NSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQ 424
            N+TAI E + R+  +F  M+ ++AF+HWY GEGM+E EF+EA  ++  L  +Y++
Sbjct: 431  NTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEE 267
>28905
          Length = 425

 Score =  259 bits (663), Expect(2) = 3e-70,   Method: Compositional matrix adjust.
 Identities = 123/129 (95%), Positives = 126/129 (97%), Gaps = 1/129 (0%)
 Frame = -1

Query: 253 LAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDSKNMMAACDPRHGRYLT 312
           +AVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFD+KNMMAACDPRHGRYLT
Sbjct: 389 VAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLT 210

Query: 313 VAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNST 372
           VAA+FRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMS TFIGNST
Sbjct: 209 VAAMFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSGTFIGNST 30

Query: 373 AIQ-ELFKR 380
           AIQ  LFKR
Sbjct: 29  AIQGRLFKR 3

 Score = 23.9 bits (50), Expect(2) = 3e-70,   Method: Composition-based stats.
 Identities = 9/9 (100%), Positives = 9/9 (100%)
 Frame = -2

Query: 242 FPGQLNADL 250
           FPGQLNADL
Sbjct: 424 FPGQLNADL 398
>31457
          Length = 1530

 Score =  255 bits (652), Expect = 2e-68,   Method: Compositional matrix adjust.
 Identities = 119/122 (97%), Positives = 122/122 (100%)
 Frame = +3

Query: 309 RYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFI 368
           +YLTVAA+FRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMS+TFI
Sbjct: 234 KYLTVAAMFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSSTFI 413

Query: 369 GNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDA 428
           GNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDA
Sbjct: 414 GNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDA 593

Query: 429 TA 430
           TA
Sbjct: 594 TA 599
>25015
          Length = 458

 Score =  240 bits (613), Expect = 8e-64,   Method: Compositional matrix adjust.
 Identities = 110/115 (95%), Positives = 113/115 (98%)
 Frame = -3

Query: 20  FWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEAAGNKYVPRAILVDLEPGTMDSVRSG 79
           FWEVISDEHGIDPTG+YHGDSDLQLERINVYYNEA G KYVPRA+LVDLEPGTMDSVRSG
Sbjct: 363 FWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEATGGKYVPRAVLVDLEPGTMDSVRSG 184

Query: 80  PFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQ 134
           PFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKE+ESCDCLQGFQ
Sbjct: 183 PFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEAESCDCLQGFQ 19
>39157
          Length = 488

 Score =  226 bits (576), Expect(2) = 7e-63,   Method: Compositional matrix adjust.
 Identities = 110/127 (86%), Positives = 116/127 (91%), Gaps = 3/127 (2%)
 Frame = -1

Query: 1   MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEAAGNKYV 60
           MREIVH+QAGQCGNQIGAKFWEVISDEHGIDPTG+YHGDSDLQLERINVYYNEA G KYV
Sbjct: 443 MREIVHLQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEATGGKYV 264

Query: 61  PRAILVDLEPGTMDSVRSG-PFG-QIFRPDNFVFGQSGAGNNWAKGHYTE-GAELVDSVL 117
           PRA+LVDLEPGTMDSVRSG PFG +IFRPDNFVFGQSGAGNNW +   T+ GAELVDSVL
Sbjct: 263 PRAVLVDLEPGTMDSVRSGSPFGPKIFRPDNFVFGQSGAGNNWGQKDTTQRGAELVDSVL 84

Query: 118 DVVRKES 124
           DVVRK  
Sbjct: 83  DVVRKRG 63

 Score = 32.7 bits (73), Expect(2) = 7e-63,   Method: Compositional matrix adjust.
 Identities = 12/13 (92%), Positives = 13/13 (100%)
 Frame = -2

Query: 122 KESESCDCLQGFQ 134
           KE+ESCDCLQGFQ
Sbjct: 70  KEAESCDCLQGFQ 32
>12457
          Length = 781

 Score =  209 bits (531), Expect = 3e-54,   Method: Compositional matrix adjust.
 Identities = 98/239 (41%), Positives = 141/239 (58%)
 Frame = -1

Query: 65  LVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKES 124
           LVDLEP  +D VR+G + Q+F P+  V G+  A NN+A+GHYT G E+VD VLD +RK +
Sbjct: 718 LVDLEPTVVDEVRTGTYRQLFHPEQLVTGKEDAANNYARGHYTIGKEIVDLVLDRIRKLA 539

Query: 125 ESCDCLQGFQXXXXXXXXXXXXXXXXXXXKIREEYPDRIMNTFSVMPSPKVSDTVVEPYN 184
           + C  LQGF                    ++  +Y  +    F++ P+P+VS  VVEPYN
Sbjct: 538 DQCTGLQGFLIFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFAIYPAPQVSTAVVEPYN 359

Query: 185 ATLSVHQLVENTDETYSIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPG 244
           + L+ H  +E++D  + +DNEA+YDIC R L +  PTY +LN L+   +S +T  LRF G
Sbjct: 358 SILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLRFDG 179

Query: 245 QLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDSKNMMAAC 303
            LN DL +   N+VP+PR+HF +  +AP+ S     +  LTV E+T   F+  N M  C
Sbjct: 178 ALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLTVAEITNACFEPANQMVKC 2
>05902
          Length = 1127

 Score =  155 bits (392), Expect = 3e-38,   Method: Compositional matrix adjust.
 Identities = 92/282 (32%), Positives = 158/282 (56%), Gaps = 12/282 (4%)
 Frame = +2

Query: 154 KIREEYPDRIMNTFSVMPS-PKVSDTVVEPYNATLSVHQLVENTDETYSIDNEALYDICF 212
           K+ + +P +++ T+SV P+  ++SD VV+PYN+ L++ +L +N D    +DN AL  I  
Sbjct: 74  KLNDRFPKKLIQTYSVFPNVDEISDVVVQPYNSLLTLKRLTQNADCVVVLDNTALNRIAA 253

Query: 213 RTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAP 272
             L + TPT+  +N LVS  MS  TT LR+PG +N DL  L  +++P PRLHF M G+ P
Sbjct: 254 DRLHIDTPTFAQVNQLVSTVMSTSTTTLRYPGYMNNDLIGLIASLIPTPRLHFLMTGYTP 433

Query: 273 LTSRGS-QQYRALTVPELTQQMFDSKNMMAACDPRHGR----YLTVAAIFRGRMSMKEVD 327
           LT+       R  TV ++ +++   KNMM +  P H +    Y+++  I +G +   +V 
Sbjct: 434 LTTDSQVANVRKTTVLDVMRRLLQPKNMMVST-PVHRQANHCYISILNIIQGEVDPTQVH 610

Query: 328 EQMLNVQNKNSSYFVEWIPNNVKTAVCDIPP---RGLKMSATFIGNSTAIQELFKRISEQ 384
           + +  ++ +  + F+ W P +++ A+    P      ++S   + N T+I  LF+RI  Q
Sbjct: 611 KSLQRIRERKLAQFIPWGPASIQVALSRKSPYVQTAHRVSGLMLANHTSISHLFERILRQ 790

Query: 385 FTAMFRRKAFLHWYTGEGM--DEM-EFTEAESNMNDLVSEYQ 423
           +  + +R+AF+  +  E +  D + EF  +   +  LV EYQ
Sbjct: 791 YDKLRKREAFMDQFKKEAIFKDNLDEFDNSREALQLLVDEYQ 916
>06360
          Length = 1896

 Score =  135 bits (340), Expect = 3e-32,   Method: Compositional matrix adjust.
 Identities = 67/179 (37%), Positives = 98/179 (54%), Gaps = 2/179 (1%)
 Frame = -1

Query: 1    MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQL--ERINVYYNEAAGNK 58
            MRE + +  GQ G Q+G   WE+   EHGI P G    D  +    +  N +++E    K
Sbjct: 1710 MRECISVHVGQAGVQMGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGK 1531

Query: 59   YVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLD 118
            +VPRA+ VDLEP  +D VR+G + Q+F P+  V G+  A NN+A+GHYT G E+VD VLD
Sbjct: 1530 HVPRAVFVDLEPTVVDEVRTGTYRQLFHPEQLVTGKEDAANNYARGHYTIGKEIVDLVLD 1351

Query: 119  VVRKESESCDCLQGFQXXXXXXXXXXXXXXXXXXXKIREEYPDRIMNTFSVMPSPKVSD 177
             +RK ++ C  LQGF                    ++  +Y  +    F++ P+P+VSD
Sbjct: 1350 RIRKLADQCTGLQGFLIFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFAIYPAPQVSD 1174
>03702
          Length = 1932

 Score =  121 bits (304), Expect = 6e-28,   Method: Compositional matrix adjust.
 Identities = 59/140 (42%), Positives = 83/140 (59%), Gaps = 1/140 (0%)
 Frame = +1

Query: 167  FSVMPSPKVSDTVVEPYNATLSVHQLVENTDETYSIDNEALYDICFRTLKLTTPTYGDLN 226
            F++ P+P+VS  VVEPYN+ L+ H  +E++D  + +DNEA+YDIC R L +  P Y +LN
Sbjct: 1501 FAIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPXYTNLN 1680

Query: 227  HLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPG-FAPLTSRGSQQYRALT 285
             L+   +S +T  LRF G LN DL +   N+VP P  H   PG   P+ S     +  LT
Sbjct: 1681 RLIGQIVSSITASLRFDGALNVDLTEFQTNLVPTP--HPLPPGHLCPVISAEKAYHEQLT 1854

Query: 286  VPELTQQMFDSKNMMAACDP 305
            V E+T   F+  N +  CDP
Sbjct: 1855 VAEVTNACFEPANQLVKCDP 1914
>17215
          Length = 632

 Score = 81.6 bits (200), Expect = 6e-16,   Method: Compositional matrix adjust.
 Identities = 36/117 (30%), Positives = 66/117 (56%), Gaps = 8/117 (6%)
 Frame = +3

Query: 316 IFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPR--------GLKMSATF 367
           ++RG +  K+V+  +  ++ K +  FV+W P   K  +   PP          ++ +   
Sbjct: 6   LYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCM 185

Query: 368 IGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQ 424
           + N+TAI E + R+  +F  M+ ++AF+HWY GEGM+E EF+EA  ++  L  +Y++
Sbjct: 186 LSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEE 356
>29025
          Length = 395

 Score = 41.6 bits (96), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 19/19 (100%), Positives = 19/19 (100%)
 Frame = -3

Query: 412 ESNMNDLVSEYQQYQDATA 430
           ESNMNDLVSEYQQYQDATA
Sbjct: 354 ESNMNDLVSEYQQYQDATA 298
>19746
          Length = 446

 Score = 38.5 bits (88), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 24/86 (27%), Positives = 39/86 (45%), Gaps = 2/86 (2%)
 Frame = +1

Query: 339 SYFVEWIPNNVKTAVCDIPPR--GLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLH 396
           S F  W   N+   V + P      + SAT + NS +       I E+   MF  +A++H
Sbjct: 55  SLFTLWTCPNMAFNVSNQPRAFCAYEKSATLVSNSRSSTRPLDDIMEKAWKMFASRAYIH 234

Query: 397 WYTGEGMDEMEFTEAESNMNDLVSEY 422
            Y   G+ E +F +A   +  +V+ Y
Sbjct: 235 QYVKRGLSEEDFLDAFVTLEQVVASY 312
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|61098092|ref|NP_057870.2| S-adenosylhomocysteine
hydrolase [Mus musculus]
         (432 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

18254                                                                 466   e-133
07987                                                                 177   7e-45
18314                                                                 151   5e-37
35116                                                                  30   1.3  
08858                                                                  30   2.5  
29384                                                                  28   5.2  
>18254
          Length = 928

 Score =  466 bits (1198), Expect(2) = e-133,   Method: Compositional matrix adjust.
 Identities = 221/291 (75%), Positives = 249/291 (85%)
 Frame = +3

Query: 124 PLNMILDDGGDLTNLIHTKYPQLLSGIRGISEETTTGVHNLYNMMSNGILKVPAINVNDS 183
           PLNMILDDGGDLTNL+H KYPQ L+GI+G+SEETTTGVHNLY MM+   LKVPAINVNDS
Sbjct: 51  PLNMILDDGGDLTNLVHEKYPQYLAGIKGLSEETTTGVHNLYRMMAEKKLKVPAINVNDS 230

Query: 184 VTKSKFDNLYGCRESLIDGIKRATDVMIAGKVAVVAGYGDVGKGCAQALRGFGARVIITE 243
           VTKSKFDNLYGCRESL+DGIKRATDVM+AGKVAVVAGYGDVGKGCAQALR FGARVIITE
Sbjct: 231 VTKSKFDNLYGCRESLVDGIKRATDVMLAGKVAVVAGYGDVGKGCAQALRAFGARVIITE 410

Query: 244 IDPINALQAAMEGYEVTTMDEACKEGNIFVTTTGCVDIILGRHFEQMKDDAIVCNIGHFD 303
           IDPINALQAAMEGYEV+T+D++  E  IFVT TGC  I+  +HFE M +D I+CNIGHFD
Sbjct: 411 IDPINALQAAMEGYEVSTIDDSLSEARIFVTATGCKGILRPKHFENMLEDTIICNIGHFD 590

Query: 304 VEIDVKWLNENAVEKVNIKPQVDRYWLKNGRRIILLAEGRLVNLGCAMGHPSFVMSNSFT 363
            EID+ WLN+N   K  ++PQV+RY +K+GR +I+LAEGRLVNLGCA GHPSFVMSNSFT
Sbjct: 591 CEIDIAWLNDNCRSKEVVQPQVERYTMKSGRHLIVLAEGRLVNLGCAHGHPSFVMSNSFT 770

Query: 364 NQVMAQIELWTHPDKYPVGVHFLPKKLDEAVAEAHLGKLNVKLTKLTEKQA 414
           NQV+AQIELWT   +Y +GVH LPKKLDE VA  HL  L VKLTKL + QA
Sbjct: 771 NQVLAQIELWTKTSQYVLGVHMLPKKLDEEVAALHLSHLGVKLTKLDDDQA 923

 Score = 29.6 bits (65), Expect(2) = e-133,   Method: Compositional matrix adjust.
 Identities = 12/13 (92%), Positives = 12/13 (92%)
 Frame = +1

Query: 109 EYLWCIEQTLHFK 121
           EYLWCIEQTL FK
Sbjct: 4   EYLWCIEQTLVFK 42
>07987
          Length = 1227

 Score =  177 bits (449), Expect = 7e-45,   Method: Compositional matrix adjust.
 Identities = 84/126 (66%), Positives = 99/126 (78%)
 Frame = -2

Query: 307  DVKWLNENAVEKVNIKPQVDRYWLKNGRRIILLAEGRLVNLGCAMGHPSFVMSNSFTNQV 366
            D+ W    ++  V ++PQV+RY +K+GR +I+LAEGRLVNLGCA GHPSFVMSNSFTNQV
Sbjct: 1157 DLTW-RPRSI*PVVVQPQVERYTMKSGRHLIVLAEGRLVNLGCAHGHPSFVMSNSFTNQV 981

Query: 367  MAQIELWTHPDKYPVGVHFLPKKLDEAVAEAHLGKLNVKLTKLTEKQAQYLGMPINGPFK 426
            +AQIELWT   +Y +GVH LPKKLDE VA  HL  L VKLTKL + QA YLG+P  GPFK
Sbjct: 980  LAQIELWTKTSQYVLGVHMLPKKLDEEVAALHLSHLGVKLTKLDDDQATYLGIPAAGPFK 801

Query: 427  PDHYRY 432
            PDHYRY
Sbjct: 800  PDHYRY 783
>18314
          Length = 475

 Score =  151 bits (382), Expect = 5e-37,   Method: Compositional matrix adjust.
 Identities = 69/127 (54%), Positives = 94/127 (74%)
 Frame = -3

Query: 16  AWGRKALDIAENEMPGLMRMREMYSASKPLKGARIAGCLHMTVETAVLIETLVALGAEVR 75
           A+GR+ ++IAE EMPGLM +R+     KPL GA+I GC H+T +TAVL+ETLVALGA VR
Sbjct: 383 AFGRREIEIAEQEMPGLMALRKRAEGDKPLHGAKIIGCTHITAQTAVLVETLVALGATVR 204

Query: 76  WSSCNIFSTQDHXXXXXXXXGIPVFAWKGETDEEYLWCIEQTLHFKDGPLNMILDDGGDL 135
           W++CNI+STQ+         GI +FAWKGET+E++ WCI++ ++ +    NMILDDGGD 
Sbjct: 203 WAACNIYSTQNEVAAALAESGICIFAWKGETEEDFWWCIDRCINAEGWQPNMILDDGGDA 24

Query: 136 TNLIHTK 142
           T+L+  K
Sbjct: 23  THLMLKK 3
>35116
          Length = 181

 Score = 30.4 bits (67), Expect = 1.3,   Method: Composition-based stats.
 Identities = 9/26 (34%), Positives = 16/26 (61%)
 Frame = +1

Query: 362 FTNQVMAQIELWTHPDKYPVGVHFLP 387
           F  Q++   + W+H D  P+ +H+LP
Sbjct: 52  FYTQLLIHTQPWSHCDGLPISLHYLP 129
>08858
          Length = 1230

 Score = 29.6 bits (65), Expect = 2.5,   Method: Compositional matrix adjust.
 Identities = 16/46 (34%), Positives = 20/46 (43%)
 Frame = -2

Query: 330 LKNGRRIILLAEGRLVNLGCAMGHPSFVMSNSFTNQVMAQIELWTH 375
           LK G  I+ +   R   L      P F   N F+  V AQ+  WTH
Sbjct: 731 LKGGYSILQIWSARQATLNKIGS*PKFAPDNFFSVFVSAQLRWWTH 594
>29384
          Length = 672

 Score = 28.5 bits (62), Expect = 5.2,   Method: Compositional matrix adjust.
 Identities = 14/25 (56%), Positives = 18/25 (72%)
 Frame = -1

Query: 35  MREMYSASKPLKGARIAGCLHMTVE 59
           +R MYS + P+ GARIAGC+  T E
Sbjct: 156 IRPMYS-NPPIHGARIAGCILNTPE 85
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6671565|ref|NP_031486.1| adaptor-related protein
complex 3, delta 1 subunit [Mus musculus]
         (1199 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

02203                                                                 472   e-133
32748                                                                 274   1e-73
09774                                                                 127   1e-55
12864                                                                 141   2e-33
>02203
          Length = 1671

 Score =  472 bits (1215), Expect = e-133,   Method: Compositional matrix adjust.
 Identities = 254/475 (53%), Positives = 312/475 (65%), Gaps = 9/475 (1%)
 Frame = +1

Query: 353 DESIRLRALDLLYGMVSKKNLMEIVKKLMTHVDKAEGTTYRDELLTKIIDICSQSNYQHI 412
           DESIRLRALDLLYGMV+KKNLMEIVKKLM H+DKAEG+ YRDELL+KII ICSQSNYQ +
Sbjct: 1   DESIRLRALDLLYGMVTKKNLMEIVKKLMVHMDKAEGSHYRDELLSKIIVICSQSNYQFV 180

Query: 413 TNFEWYISILVELTRLEGTRHGHLIAAQMLDVAIRVKAIRKFAVSQMSSLLDSAHLVASS 472
           TNFEWY+SILVELTR+EGTRHG +IAAQMLDVAIRV+AIR FAVSQM+ LL+++HL+A++
Sbjct: 181 TNFEWYVSILVELTRMEGTRHGGMIAAQMLDVAIRVQAIRHFAVSQMAILLENSHLLANN 360

Query: 473 TQRNGICEVLYAAAWICGEFSEHLQGPQQTLEAMLRPKVTTLPGHIQAVYVQNVVKLYAS 532
           +QRNGICEVLYAAAWICGEFSEHL+ PQQTLEAMLRPK+T+LPGHIQ+V+VQN++KLY  
Sbjct: 361 SQRNGICEVLYAAAWICGEFSEHLKEPQQTLEAMLRPKLTSLPGHIQSVFVQNLLKLYCK 540

Query: 533 ILQQKEQAADTEAAQEVTQLLVERLPQFVQSADLEVQERASCILQLVKHVQKLQAKGVPV 592
           ++++ E   D E   +V   L E+LP FVQS DLEVQERA  +L LVK+V K++ KGV V
Sbjct: 541 VVRRLEDEDDQEGINQVHTTLQEKLPVFVQSGDLEVQERACSMLGLVKYVIKIREKGVTV 720

Query: 593 AEEVSALFAGELNPVAPKAQKKVPVPEGLDLDAWINXXXXXXXXXXXXXXAIFH----EE 648
            +E+++L+AGELNPVA KAQ+KVPVPEGLDLDAWIN                F      +
Sbjct: 721 GDELASLYAGELNPVATKAQRKVPVPEGLDLDAWINQPESDSSDEEEAMGVGFFSSVXSD 900

Query: 649 EPRHTXXXXXXX-----XXXXXXXXXXXXXXXXXNNPFYIKSSPSPQKRYQDAPGVEHIP 703
           E R                               +NP Y+K   S +K  + +  V  IP
Sbjct: 901 EHRSAYQLEPSKQVPEPTAEELEKRREARRTEQEHNPHYLKDDGSRKKSKRSSNDVSVIP 1080

Query: 704 VVQIDLSVPLKVPGMPMSDQYVKXXXXXXXXXXXXXXXXXXXXXXXXXXHSSLPTESDED 763
           V  IDLSVPL VPG+  SD+Y++                               +E + +
Sbjct: 1081VTPIDLSVPLHVPGLSSSDKYMQLDNQKDSGRGRKEGKSRKKGKKKRRKGKESESEEEVE 1260

Query: 764 IAPAQRVDIITEEMPENALPSDEDDKDPNDPYRALDIDLDKPLADSEKLPVQKHR 818
              A    +   +  E A    EDD D  DPY+ LDI+LD PL D E +PV  HR
Sbjct: 1261QMHAVSTVLDAPDGVEGA-SDKEDDGDNKDPYKMLDINLDAPLRDDETIPVPTHR 1422

 Score = 94.7 bits (234), Expect = 2e-19,   Method: Compositional matrix adjust.
 Identities = 40/66 (60%), Positives = 53/66 (80%)
 Frame = +3

Query: 484  AAAWICGEFSEHLQGPQQTLEAMLRPKVTTLPGHIQAVYVQNVVKLYASILQQKEQAADT 543
              +WICGEFSEHL+ PQQTLEAMLRPK+T+LPGHIQ+V+VQN++KLY  ++++ E   D 
Sbjct: 1458 GCSWICGEFSEHLKEPQQTLEAMLRPKLTSLPGHIQSVFVQNLLKLYCKVVRRLEDEDDQ 1637

Query: 544  EAAQEV 549
            E   +V
Sbjct: 1638 EGINQV 1655
>32748
          Length = 429

 Score =  274 bits (701), Expect = 1e-73,   Method: Compositional matrix adjust.
 Identities = 131/138 (94%), Positives = 137/138 (99%)
 Frame = -3

Query: 187 RLKEKLEDPDPGVQSAAVNVICELARRNPKNYLSLAPLFFKLMTSSTNNWVLIKIIKLFG 246
           R KEKLEDPDPGVQSAAVNVICELAR+NPKNYLSLAPLFFKLMT+STNNWVLIKIIKLFG
Sbjct: 415 RXKEKLEDPDPGVQSAAVNVICELARKNPKNYLSLAPLFFKLMTTSTNNWVLIKIIKLFG 236

Query: 247 ALTPLEPRLGKKLIEPLTNLIHSTSAMSLLYECVNTVIAVLISLSSGMPNHSASIQLCVQ 306
           ALTPLEPRLGKKLIEPLTNLIHSTSAMSLLYEC+NTVIAVL+S+SSG+PNHSASIQLCVQ
Sbjct: 235 ALTPLEPRLGKKLIEPLTNLIHSTSAMSLLYECINTVIAVLVSISSGIPNHSASIQLCVQ 56

Query: 307 KLRILIEDSDQNLKYLGL 324
           KLRILIEDSDQNLKYLGL
Sbjct: 55  KLRILIEDSDQNLKYLGL 2
>09774
          Length = 1829

 Score =  127 bits (319), Expect(2) = 1e-55,   Method: Compositional matrix adjust.
 Identities = 60/117 (51%), Positives = 81/117 (69%)
 Frame = +2

Query: 965  MSSYCLLAESPYIKVTYDIQASLQKDSQVTVSIILENQSSSFLKNMELNVLDSLNTKMTR 1024
            MSSY LLA++  +K+TY+++ + Q+ +QV VSI+  N S   LK++E NVLD+LNTK+ R
Sbjct: 1082 MSSYKLLADNASVKLTYEVRINHQRSNQVVVSIVFANLSPQTLKDLEFNVLDTLNTKLIR 1261

Query: 1025 PEGSSVHDGVPVPFQLPPGVSNEAQFVFTIQSIVMAQKLKGTLSFIAKDDEGATHEK 1081
              G   HD V VPF LPPG  NE QF FT+  I   QKL+GTL++I K  +G+T EK
Sbjct: 1262 GLGQKHHDAVKVPFTLPPGAQNEGQFAFTVDDITAPQKLRGTLTYILKSADGSTQEK 1432

 Score =  109 bits (272), Expect(2) = 1e-55,   Method: Compositional matrix adjust.
 Identities = 55/115 (47%), Positives = 80/115 (69%), Gaps = 1/115 (0%)
 Frame = +1

Query: 1081 KLDFRLHFSCSSYLITTPCYSDAFAKLLESGDLSM-NSIKVDGISMSFQNLLAKICFYHH 1139
            K+DFR+   C SYL+T+PC S+ FA LL  GDL+   S KV+   + F +LLA+I F+ H
Sbjct: 1429 KVDFRIALPCCSYLLTSPCKSEDFASLLSGGDLTAKGSAKVEVEGVPFAHLLARISFFTH 1608

Query: 1140 FSVVERVDSCASMYSRSIQGHHVCLLVKKGESSVSVDGKCSDATLLSSLLEEMKT 1194
            F VVE+V   AS++SRSIQ H VCLLVK    ++++DGK +    L+++LE++K+
Sbjct: 1609 FRVVEQVAESASLFSRSIQDHPVCLLVKMTNGALAIDGKSTHEGFLANVLEDIKS 1773

 Score = 46.6 bits (109), Expect = 6e-05,   Method: Composition-based stats.
 Identities = 20/33 (60%), Positives = 23/33 (69%)
 Frame = +3

Query: 786 EDDKDPNDPYRALDIDLDKPLADSEKLPVQKHR 818
           EDD D  DPY+ LDI+LD PL D E +PV  HR
Sbjct: 315 EDDGDNKDPYKMLDINLDAPLRDDETIPVPTHR 413

 Score = 37.0 bits (84), Expect = 0.044,   Method: Compositional matrix adjust.
 Identities = 16/25 (64%), Positives = 20/25 (80%)
 Frame = +2

Query: 702 IPVVQIDLSVPLKVPGMPMSDQYVK 726
           IPV  IDLSVPL VPG+  SD+Y++
Sbjct: 65  IPVTPIDLSVPLHVPGLSSSDKYMQ 139
>12864
          Length = 1210

 Score =  141 bits (355), Expect = 2e-33,   Method: Compositional matrix adjust.
 Identities = 73/155 (47%), Positives = 103/155 (66%), Gaps = 6/155 (3%)
 Frame = +2

Query: 1046 NEAQFVFTIQSIVMAQKLKGTLSFIAKDDEGATHEKLDFRLHFSCSSYLITTPC-----Y 1100
            NE QF FT+  I   QKL+GTL++I K  +G+T EK+DFR+   C SYL+T+PC      
Sbjct: 8    NEGQFAFTVDDITAPQKLRGTLTYILKSADGSTQEKVDFRIALPCCSYLLTSPCKSVCDC 187

Query: 1101 SDAFAKLLESGDLSM-NSIKVDGISMSFQNLLAKICFYHHFSVVERVDSCASMYSRSIQG 1159
            S+ FA LL  GDL+   S KV+   + F +LLA+I F+ HF VVE+V   AS++SRSIQ 
Sbjct: 188  SEDFASLLSGGDLTAKGSAKVEVEGVPFAHLLARISFFTHFRVVEQVAESASLFSRSIQD 367

Query: 1160 HHVCLLVKKGESSVSVDGKCSDATLLSSLLEEMKT 1194
            H VCLLVK    ++++DGK +    L++ LE++K+
Sbjct: 368  HPVCLLVKMTNGALAIDGKSTHEGFLANXLEDIKS 472
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6680047|ref|NP_032169.1| guanine nucleotide binding
protein (G protein), beta polypeptide 2 like 1 [Mus musculus]
         (317 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

00561                                                                 414   e-133
17598                                                                 266   7e-72
12806                                                                 243   7e-65
07665                                                                 156   1e-38
13335                                                                  82   2e-16
01327                                                                  80   1e-15
02147                                                                  75   3e-14
03156                                                                  71   5e-13
30256                                                                  71   5e-13
19949                                                                  68   5e-12
27465                                                                  66   1e-11
03387                                                                  65   3e-11
12574                                                                  62   2e-10
17602                                                                  62   3e-10
03395                                                                  61   7e-10
18981                                                                  59   2e-09
12960                                                                  57   8e-09
02090                                                                  57   1e-08
02960                                                                  53   1e-07
11493                                                                  52   3e-07
13278                                                                  51   5e-07
21105                                                                  50   2e-06
37180                                                                  49   3e-06
19498                                                                  48   5e-06
17266                                                                  47   8e-06
01768                                                                  47   1e-05
01249                                                                  47   1e-05
26107                                                                  45   3e-05
19140                                                                  45   4e-05
33180                                                                  45   5e-05
01462                                                                  44   7e-05
19863                                                                  44   7e-05
26939                                                                  44   8e-05
30295                                                                  43   1e-04
04088                                                                  43   2e-04
15780                                                                  43   2e-04
01598                                                                  42   2e-04
15118                                                                  42   4e-04
16105                                                                  41   6e-04
14555                                                                  40   0.001
21921                                                                  40   0.001
31384                                                                  40   0.001
10264                                                                  39   0.002
31054                                                                  39   0.003
25880                                                                  39   0.003
14500                                                                  38   0.004
10162                                                                  38   0.004
04524                                                                  36   0.021
31864                                                                  36   0.021
29912                                                                  36   0.022
11915                                                                  36   0.024
27270                                                                  35   0.027
13890                                                                  35   0.028
34005                                                                  35   0.033
31474                                                                  35   0.045
05642                                                                  35   0.055
15972                                                                  34   0.066
35607                                                                  34   0.087
15337                                                                  33   0.10 
17807                                                                  33   0.13 
17298                                                                  33   0.15 
00825                                                                  33   0.15 
20662                                                                  33   0.18 
16199                                                                  32   0.28 
12140                                                                  32   0.33 
27475                                                                  32   0.41 
12841                                                                  32   0.42 
15745                                                                  31   0.58 
27681                                                                  31   0.78 
03734                                                                  30   0.90 
34511                                                                  30   1.2  
31118                                                                  30   1.3  
27806                                                                  30   1.6  
01805                                                                  29   2.1  
18320                                                                  29   2.5  
07781                                                                  29   2.6  
35695                                                                  28   3.6  
30108                                                                  27   9.9  
>00561
          Length = 1003

 Score =  414 bits (1065), Expect(2) = e-133,   Method: Compositional matrix adjust.
 Identities = 197/247 (79%), Positives = 218/247 (88%), Gaps = 1/247 (0%)
 Frame = -3

Query: 19   TQIATTPQFPDMILSASRDKTIIMWKLTRDE-TNYGIPQRALRGHSHFVSDVVISSDGQF 77
            TQIAT P+ PD I+SASRDKT+I+WKLTRDE TNYG PQ+ L GHSHF+SDVV+SSDG +
Sbjct: 1001 TQIATNPKDPDTIISASRDKTLIVWKLTRDEDTNYGYPQKRLYGHSHFISDVVLSSDGNY 822

Query: 78   ALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGV 137
            ALSGSWD TLRLWDL  G TTRRF GHTKDVLSVAFS+DNRQIVSGSRDKTIKLWNTL  
Sbjct: 821  ALSGSWDQTLRLWDLAAGKTTRRFEGHTKDVLSVAFSADNRQIVSGSRDKTIKLWNTLAE 642

Query: 138  CKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNT 197
            CK+T+Q++ H++WVSCVRFSPN SNPIIVSCGWD+ VKVWNLANCKLK NH GH GYLNT
Sbjct: 641  CKFTIQEDGHTDWVSCVRFSPNHSNPIIVSCGWDRTVKVWNLANCKLKNNHHGHNGYLNT 462

Query: 198  VTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDIINALCFSPNRYWLCAATGPSIK 257
            VTVSPDGSLC SGGKD +A+LWDLN+GK+LYTL+  DIINALCFSPNRYWLC A GPSIK
Sbjct: 461  VTVSPDGSLCTSGGKDSKALLWDLNDGKNLYTLEHNDIINALCFSPNRYWLCVAYGPSIK 282

Query: 258  IWDLEGK 264
            IWDL  K
Sbjct: 281  IWDLACK 261

 Score = 78.2 bits (191), Expect(2) = e-133,   Method: Compositional matrix adjust.
 Identities = 34/48 (70%), Positives = 42/48 (87%)
 Frame = -2

Query: 267 VDELKQEVISTSSKAEPPQCTSLAWSADGQTLFAGYTDNLVRVWQVTI 314
           V+EL+ EV+S +SKAE PQC SLAWS DGQTLFAGY+DN +RVWQV++
Sbjct: 255 VEELRPEVVSPTSKAEQPQCLSLAWSTDGQTLFAGYSDNTIRVWQVSV 112

 Score = 30.0 bits (66), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 17/86 (19%), Positives = 41/86 (47%)
 Frame = -3

Query: 7   LRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFV 66
           L+    GHNG++  +  +P    +  S  +D   ++W L   +  Y +       H+  +
Sbjct: 503 LKNNHHGHNGYLNTVTVSPDG-SLCTSGGKDSKALLWDLNDGKNLYTL------EHNDII 345

Query: 67  SDVVISSDGQFALSGSWDGTLRLWDL 92
           + +  S + ++ L  ++  ++++WDL
Sbjct: 344 NALCFSPN-RYWLCVAYGPSIKIWDL 270

 Score = 29.6 bits (65), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 36/165 (21%), Positives = 60/165 (36%), Gaps = 8/165 (4%)
 Frame = -3

Query: 155 RFSPNSSNP-IIVSCGWDKLVKVWNLANCKLKTNH-------IGHTGYLNTVTVSPDGSL 206
           + + N  +P  I+S   DK + VW L      TN+        GH+ +++ V +S DG+ 
Sbjct: 998 QIATNPKDPDTIISASRDKTLIVWKLTR-DEDTNYGYPQKRLYGHSHFISDVVLSSDGNY 822

Query: 207 CASGGKDGQAMLWDLNEGKHLYTLDGGDIINALCFSPNRYWLCAATGPSIKIWDLEGKII 266
             SG  D    LWDL  GK     +G                                  
Sbjct: 821 ALSGSWDQTLRLWDLAAGKTTRRFEGH--------------------------------- 741

Query: 267 VDELKQEVISTSSKAEPPQCTSLAWSADGQTLFAGYTDNLVRVWQ 311
                ++V+S            +A+SAD + + +G  D  +++W 
Sbjct: 740 ----TKDVLS------------VAFSADNRQIVSGSRDKTIKLWN 654
>17598
          Length = 875

 Score =  266 bits (681), Expect = 7e-72,   Method: Compositional matrix adjust.
 Identities = 129/283 (45%), Positives = 180/283 (63%), Gaps = 8/283 (2%)
 Frame = +1

Query: 29  DMILSASRDKTIIMWKLT------RDETNYGIPQRALRGHSHFVSDVVISSDGQFALSGS 82
           + ++   RDK +I+W L        DET +G P+R L+GHSHFVSDV +S+D ++ LS S
Sbjct: 4   EFLIXGGRDKLLIVWDLVPRKDGDEDET-WGGPRRTLQGHSHFVSDVSLSADSRYVLSSS 180

Query: 83  WDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTV 142
           WD TLRLWD+  G TTRRF+ HT+D L+VAFS DNRQI SG RDK +K+WNT+G CK+TV
Sbjct: 181 WDATLRLWDIKKGNTTRRFISHTRDALAVAFSPDNRQIASGGRDKALKIWNTVGECKFTV 360

Query: 143 QDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSP 202
              SH +WV+CV+F  ++ +P++VS   DK +KVW+     LK   +GH   +N + ++ 
Sbjct: 361 DANSHQDWVTCVKFHQDAKSPLVVSASMDKTIKVWDNQTMTLKHTFVGHKTQINAIDLAL 540

Query: 203 DGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDIINALCFSPNRYWLCAATGPSIKIWDLE 262
                ASG KDG  M W++  G  L  +D    +NA+ FSPN+YWL   T   I+IWDL 
Sbjct: 541 KTYYLASGSKDGIVMTWNIQNGTFLGKIDCDCEVNAVKFSPNKYWLFVGTSEGIQIWDLP 720

Query: 263 GKIIVDELKQEVISTSSKAEPPQ--CTSLAWSADGQTLFAGYT 303
            +  + +++   I    K++     CTSLAW A G TLFAG++
Sbjct: 721 NQKKIKDIRASPIDAQHKSQKKSIACTSLAWDASGHTLFAGFS 849
>12806
          Length = 961

 Score =  243 bits (620), Expect = 7e-65,   Method: Compositional matrix adjust.
 Identities = 127/284 (44%), Positives = 176/284 (61%), Gaps = 12/284 (4%)
 Frame = +3

Query: 22  ATTPQFPDMILSASRDKTIIMWKL------TRDETNYGIPQRALRGHSHFVSDVVISSDG 75
           AT P     ++S  RD  II+W L        D+T +G+P++ L GHSHF+SD+ +S+D 
Sbjct: 39  ATKP----FLISGGRDNNIIVWDL*PKKDGDEDQT-WGVPRKTLTGHSHFISDLALSADS 203

Query: 76  QFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTL 135
           +FALS SWD TLRLWD+  G+TT RF+ HT+DVL+VAFS DNRQI SG RDK +K+WN +
Sbjct: 204 RFALSSSWDATLRLWDIKKGSTTSRFINHTRDVLTVAFSPDNRQIASGGRDKNLKIWNIM 383

Query: 136 GVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYL 195
           G CKYTV   +H++WV+CVRF  ++ NPI+VS   DK +KVW+     LK   +GH   +
Sbjct: 384 GECKYTVDANAHTDWVTCVRFHQDTKNPIVVSASNDKTIKVWDNHTMTLKNTFVGHKAQI 563

Query: 196 NTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDIINALCF----SPNRYWLCAA 251
             + +S +     SG KDG AM W++ EG  +  +D  D INA+ F    +  + WL   
Sbjct: 564 TALDMSTN--YLVSGSKDGIAMTWNVAEGSFVGKIDCDDQINAIKFNIENNKKKVWLFIG 737

Query: 252 TGPSIKIWDLEGKIIVDELKQEVI--STSSKAEPPQCTSLAWSA 293
           T   I+IWD  G+  + ELK   I    + + +P  CTSLA +A
Sbjct: 738 TQNGIQIWDYSGEKKIKELKASPIDPQNAKQKKPIACTSLASTA 869

 Score = 30.4 bits (67), Expect = 0.88,   Method: Compositional matrix adjust.
 Identities = 25/92 (27%), Positives = 45/92 (48%), Gaps = 1/92 (1%)
 Frame = +3

Query: 13  GHNGWVTQIATTPQFPD-MILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVI 71
            H  WVT +       + +++SAS DKTI +W     + +    +    GH   ++ + +
Sbjct: 414 AHTDWVTCVRFHQDTKNPIVVSASNDKTIKVW-----DNHTMTLKNTFVGHKAQITALDM 578

Query: 72  SSDGQFALSGSWDGTLRLWDLTTGTTTRRFVG 103
           S++  + +SGS DG    W++  G+    FVG
Sbjct: 579 STN--YLVSGSKDGIAMTWNVAEGS----FVG 656
>07665
          Length = 435

 Score =  156 bits (395), Expect = 1e-38,   Method: Compositional matrix adjust.
 Identities = 71/99 (71%), Positives = 82/99 (82%)
 Frame = -2

Query: 219 WDLNEGKHLYTLDGGDIINALCFSPNRYWLCAATGPSIKIWDLEGKIIVDELKQEVISTS 278
           WDLN+GK+LYTL+  DIINALCFSPNRYWLC A GPSIKIWDL  K  V+EL+ EV+S +
Sbjct: 392 WDLNDGKNLYTLEHNDIINALCFSPNRYWLCVAYGPSIKIWDLACKKTVEELRPEVVSPT 213

Query: 279 SKAEPPQCTSLAWSADGQTLFAGYTDNLVRVWQVTIGTR 317
           SKAE PQC SLAWS DGQTLFAGY+DN +RVWQV++   
Sbjct: 212 SKAEQPQCLSLAWSTDGQTLFAGYSDNTIRVWQVSVSAH 96
>13335
          Length = 863

 Score = 82.4 bits (202), Expect = 2e-16,   Method: Compositional matrix adjust.
 Identities = 61/206 (29%), Positives = 104/206 (50%), Gaps = 23/206 (11%)
 Frame = +1

Query: 79  LSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWN-TLGV 137
           +SGS D T+ +W++ T    R +VGH   V+++A+S +   +VSGS +  + +W+ + G 
Sbjct: 109 VSGSDDDTICMWEVATQKLVRSYVGHEDSVMALAYSPNGHYLVSGSPNGDLYVWDASFGH 288

Query: 138 CKY-TVQDESHSEWVSCVRFSP--------NSS--NPIIVSCGWDKLVKVWNLA------ 180
           C++ T++ ++H   V+C  FSP        NSS  N ++ + G D L+K+W  +      
Sbjct: 289 CRHLTLRVDAHDLGVTCCEFSPTFGTACAENSSTCNLLLATGGKDNLIKLWTFSAQVGSP 468

Query: 181 NCKLKTNHI--GHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDG--GDII 236
              L+   I  GH+  +     SP  +L ASG  D    LWD  +G  L++++      +
Sbjct: 469 EVTLQCRDILSGHSDLVMACAFSPSSALLASGSFDKSVRLWDSVKGVALFSIEACHSRFV 648

Query: 237 NALCFSPNRYWLCAATGPS-IKIWDL 261
               FS +   L + +    IKIW L
Sbjct: 649 TCCAFSIDGTLLASGSMDRIIKIWKL 726

 Score = 68.2 bits (165), Expect = 5e-12,   Method: Compositional matrix adjust.
 Identities = 61/216 (28%), Positives = 98/216 (45%), Gaps = 23/216 (10%)
 Frame = +1

Query: 31  ILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVISSDGQFALSGSWDGTLRLW 90
           ++S S D TI MW++   +       R+  GH   V  +  S +G + +SGS +G L +W
Sbjct: 106 LVSGSDDDTICMWEVATQKL-----VRSYVGHEDSVMALAYSPNGHYLVSGSPNGDLYVW 270

Query: 91  DLTTGTT---TRRFVGHTKDVLSVAF------------SSDNRQIVSGSRDKTIKLWN-- 133
           D + G     T R   H   V    F            S+ N  + +G +D  IKLW   
Sbjct: 271 DASFGHCRHLTLRVDAHDLGVTCCEFSPTFGTACAENSSTCNLLLATGGKDNLIKLWTFS 450

Query: 134 -TLGVCKYTVQDES----HSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWN-LANCKLKTN 187
             +G  + T+Q       HS+ V    FSP+S+  ++ S  +DK V++W+ +    L + 
Sbjct: 451 AQVGSPEVTLQCRDILSGHSDLVMACAFSPSSA--LLASGSFDKSVRLWDSVKGVALFSI 624

Query: 188 HIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNE 223
              H+ ++     S DG+L ASG  D    +W L +
Sbjct: 625 EACHSRFVTCCAFSIDGTLLASGSMDRIIKIWKLTD 732

 Score = 57.4 bits (137), Expect = 8e-09,   Method: Compositional matrix adjust.
 Identities = 63/249 (25%), Positives = 104/249 (41%), Gaps = 24/249 (9%)
 Frame = +1

Query: 89  LWDLTTGTTTRRFVGHTKDVLSVA-FSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDESH 147
           +WD+ TG+    +   +K  + V  FS  +  +VSGS D TI +W  +   K       H
Sbjct: 10  VWDVKTGSIKGEYQHASKSSIRVCKFSPSSSHLVSGSDDDTICMWE-VATQKLVRSYVGH 186

Query: 148 SEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHI-GHTGYLNTVTVSPD-GS 205
            + V  + +SPN    +  S   D  V   +  +C+  T  +  H   +     SP  G+
Sbjct: 187 EDSVMALAYSPNGHYLVSGSPNGDLYVWDASFGHCRHLTLRVDAHDLGVTCCEFSPTFGT 366

Query: 206 LC-----------ASGGKDGQAMLWDLNE--GKHLYTLDGGDIIN-------ALCFSPNR 245
            C           A+GGKD    LW  +   G    TL   DI++       A  FSP+ 
Sbjct: 367 ACAENSSTCNLLLATGGKDNLIKLWTFSAQVGSPEVTLQCRDILSGHSDLVMACAFSPSS 546

Query: 246 YWLCAAT-GPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFAGYTD 304
             L + +   S+++W        D +K   + +         T  A+S DG  L +G  D
Sbjct: 547 ALLASGSFDKSVRLW--------DSVKGVALFSIEACHSRFVTCCAFSIDGTLLASGSMD 702

Query: 305 NLVRVWQVT 313
            ++++W++T
Sbjct: 703 RIIKIWKLT 729

 Score = 52.0 bits (123), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 41/149 (27%), Positives = 61/149 (40%), Gaps = 18/149 (12%)
 Frame = +1

Query: 3   EQMTLRGTLKGHNGWVTQIATTPQFPD-----------MILSASRDKTIIMWKLTRDETN 51
             +TLR  +  H+  VT    +P F             ++ +  +D  I +W  +     
Sbjct: 292 RHLTLR--VDAHDLGVTCCEFSPTFGTACAENSSTCNLLLATGGKDNLIKLWTFS---AQ 456

Query: 52  YGIPQRALR------GHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVG-H 104
            G P+  L+      GHS  V     S       SGS+D ++RLWD   G         H
Sbjct: 457 VGSPEVTLQCRDILSGHSDLVMACAFSPSSALLASGSFDKSVRLWDSVKGVALFSIEACH 636

Query: 105 TKDVLSVAFSSDNRQIVSGSRDKTIKLWN 133
           ++ V   AFS D   + SGS D+ IK+W 
Sbjct: 637 SRFVTCCAFSIDGTLLASGSMDRIIKIWK 723

 Score = 43.5 bits (101), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 27/89 (30%), Positives = 41/89 (46%)
 Frame = +1

Query: 5   MTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSH 64
           +  R  L GH+  V   A +P    ++ S S DK++ +W   +    + I       HS 
Sbjct: 478 LQCRDILSGHSDLVMACAFSPS-SALLASGSFDKSVRLWDSVKGVALFSIEA----CHSR 642

Query: 65  FVSDVVISSDGQFALSGSWDGTLRLWDLT 93
           FV+    S DG    SGS D  +++W LT
Sbjct: 643 FVTCCAFSIDGTLLASGSMDRIIKIWKLT 729
>01327
          Length = 2215

 Score = 80.1 bits (196), Expect = 1e-15,   Method: Compositional matrix adjust.
 Identities = 66/257 (25%), Positives = 118/257 (45%), Gaps = 11/257 (4%)
 Frame = +3

Query: 28  PDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVISSDGQFALSGSWDGTL 87
           P + LS S+DK+++++    D  N  +  R   GH   ++ V   +      S S D T+
Sbjct: 75  PGLCLSGSKDKSVVLY----DYQNGRLEDR-WTGHDREITKVCYGASCNGMFSASRDKTI 239

Query: 88  RLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNT-LGVCKYTVQDES 146
           ++W      + R F+GH   V ++  ++DN  + SGSRD T+++W+   G C    Q+  
Sbjct: 240 KMWQRGNSHSIRDFIGHDMVVTAIHLNTDNTLLCSGSRDNTVRIWDVETGAC--LRQNNI 413

Query: 147 HSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSL 206
               V+ V++ P S   +I+  G DK V++++     +  +         +  V+ DG  
Sbjct: 414 PQNLVTDVKWLPGSH--LIIQAGEDKEVRIYDSRTLGIVRSFTKKQYIQMSCDVTADGQF 587

Query: 207 CAS-----GGKDGQAMLWDLNEGKHLYTLDGG-DIINALCFSPNRYWL----CAATGPSI 256
           C +     GG   +A LW L++G       G  + I A  F P+   +     A+   S+
Sbjct: 588 CLTCSNGFGGNGCEATLWQLSDGSIQNEFKGHREAIEACLFLPSNQDMTLIATASRDCSV 767

Query: 257 KIWDLEGKIIVDELKQE 273
           ++W++  K  V E   E
Sbjct: 768 RVWNMFTKECVCEQNFE 818
>02147
          Length = 1547

 Score = 75.5 bits (184), Expect = 3e-14,   Method: Compositional matrix adjust.
 Identities = 69/255 (27%), Positives = 108/255 (42%), Gaps = 38/255 (14%)
 Frame = +2

Query: 9   GTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSD 68
           GT +GH G V   AT  +      + + D +  +W   + E      +     H H V  
Sbjct: 155 GTFEGHKGAVWG-ATLNREATRAATGAADFSAKIWDAEKGE------ELQTFSHKHIVKS 313

Query: 69  VVISSDGQFALSGSWDGTLRLWDL-TTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDK 127
           V  S DG   L+GS +  L+++DL  T    + F GHT ++    F SD ++I+S S DK
Sbjct: 314 VDFSHDGTALLTGSNEKLLKVFDLVNTDAEPKSFAGHTSNIKGALFLSDGKRIISASDDK 493

Query: 128 TIKLWNTLGVCKYTVQ--------------DE-----SHSEWVSCVR------------- 155
           T++LW +L  C+   Q              D+     +HS+ ++  +             
Sbjct: 494 TVRLW-SLETCQEVQQLTFDTPPTSLTLSPDKNTIIVTHSQNIAFYQADTLREMKKFEAE 670

Query: 156 -----FSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCASG 210
                 S + S    V+ G D  +  ++    K   +  GH G ++ V  SPDG L ASG
Sbjct: 671 APISSASLHQSERFFVAGGEDFKMYKFDYETGKEIESFKGHFGPVHCVRFSPDGELYASG 850

Query: 211 GKDGQAMLWDLNEGK 225
            +DG   LW    G+
Sbjct: 851 SEDGTLRLWQTTIGR 895

 Score = 63.2 bits (152), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 56/257 (21%), Positives = 108/257 (42%)
 Frame = +2

Query: 59  LRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNR 118
             GH   V    ++ +   A +G+ D + ++WD   G   + F  H   V SV FS D  
Sbjct: 161 FEGHKGAVWGATLNREATRAATGAADFSAKIWDAEKGEELQTF-SHKHIVKSVDFSHDGT 337

Query: 119 QIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWN 178
            +++GS +K +K+++ +           H+  +    F  +     I+S   DK V++W+
Sbjct: 338 ALLTGSNEKLLKVFDLVNTDAEPKSFAGHTSNIKGALFLSDGKR--IISASDDKTVRLWS 511

Query: 179 LANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDIINA 238
           L  C+ +   +       ++T+SPD +          A  +  +  + +   +    I++
Sbjct: 512 LETCQ-EVQQLTFDTPPTSLTLSPDKNTIIVTHSQNIA-FYQADTLREMKKFEAEAPISS 685

Query: 239 LCFSPNRYWLCAATGPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTL 298
                +  +  A  G   K++  +      E  +E+ S      P  C  + +S DG+  
Sbjct: 686 ASLHQSERFFVAG-GEDFKMYKFDY-----ETGKEIESFKGHFGPVHC--VRFSPDGELY 841

Query: 299 FAGYTDNLVRVWQVTIG 315
            +G  D  +R+WQ TIG
Sbjct: 842 ASGSEDGTLRLWQTTIG 892

 Score = 47.4 bits (111), Expect = 7e-06,   Method: Compositional matrix adjust.
 Identities = 39/132 (29%), Positives = 58/132 (43%), Gaps = 10/132 (7%)
 Frame = +2

Query: 28  PDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVISSDG-----QFALSGS 82
           P   L+ S DK  I+   +++   Y      LR    F ++  ISS       +F ++G 
Sbjct: 554 PPTSLTLSPDKNTIIVTHSQNIAFY--QADTLREMKKFEAEAPISSASLHQSERFFVAGG 727

Query: 83  WDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWN-----TLGV 137
            D  +  +D  TG     F GH   V  V FS D     SGS D T++LW      T G+
Sbjct: 728 EDFKMYKFDYETGKEIESFKGHFGPVHCVRFSPDGELYASGSEDGTLRLWQTTIGRTYGL 907

Query: 138 CKYTVQDESHSE 149
            K  + DE+ ++
Sbjct: 908 WKCVIPDEADAQ 943
>03156
          Length = 1014

 Score = 71.2 bits (173), Expect = 5e-13,   Method: Compositional matrix adjust.
 Identities = 57/224 (25%), Positives = 101/224 (45%), Gaps = 11/224 (4%)
 Frame = +1

Query: 61  GHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQI 120
           GH   ++ V   +      S S D T+++W      + R F+GH   V ++  ++DN  +
Sbjct: 49  GHDREITKVCYGASCNGMFSASRDKTIKMWQRGNSHSIRDFIGHDMVVTAIHLNTDNTLL 228

Query: 121 VSGSRDKTIKLWNT-LGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNL 179
            SGSRD T+++W+   G C    Q+      V+ V++ P S   +I+  G DK V++++ 
Sbjct: 229 CSGSRDNTVRIWDVETGACLR--QNNIPQNLVTDVKWLPGSH--LIIQAGEDKEVRIYDS 396

Query: 180 ANCKLKTNHIGHTGYLNTVTVSPDGSLCAS-----GGKDGQAMLWDLNEGKHLYTLDGG- 233
               +  +         +  V+ DG  C +     GG   +A LW L++G       G  
Sbjct: 397 RTLGIVRSFTKKQYIQMSCDVTADGQFCLTCSNGFGGNGCEATLWQLSDGSIQNEFKGHR 576

Query: 234 DIINALCFSPNRYWL----CAATGPSIKIWDLEGKIIVDELKQE 273
           + I A  F P+   +     A+   S+++W++  K  V E   E
Sbjct: 577 EAIEACLFLPSNQDMTLIATASRDCSVRVWNMFTKECVCEQNFE 708

 Score = 58.5 bits (140), Expect = 4e-09,   Method: Compositional matrix adjust.
 Identities = 51/219 (23%), Positives = 96/219 (43%), Gaps = 10/219 (4%)
 Frame = +1

Query: 13  GHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVIS 72
           GH+  +T++        M  SASRDKTI MW+     +      R   GH   V+ + ++
Sbjct: 49  GHDREITKVCYGASCNGM-FSASRDKTIKMWQRGNSHS-----IRDFIGHDMVVTAIHLN 210

Query: 73  SDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLW 132
           +D     SGS D T+R+WD+ TG   R+       V  V +   +  I+    DK ++++
Sbjct: 211 TDNTLLCSGSRDNTVRIWDVETGACLRQNNIPQNLVTDVKWLPGSHLIIQAGEDKEVRIY 390

Query: 133 N--TLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSC-----GWDKLVKVWNLANCKLK 185
           +  TLG+    V+  +  +++  +     +     ++C     G      +W L++  ++
Sbjct: 391 DSRTLGI----VRSFTKKQYIQ-MSCDVTADGQFCLTCSNGFGGNGCEATLWQLSDGSIQ 555

Query: 186 TNHIGHTGYLNTVTVSP---DGSLCASGGKDGQAMLWDL 221
               GH   +      P   D +L A+  +D    +W++
Sbjct: 556 NEFKGHREAIEACLFLPSNQDMTLIATASRDCSVRVWNM 672

 Score = 45.4 bits (106), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 52/236 (22%), Positives = 90/236 (38%), Gaps = 9/236 (3%)
 Frame = +1

Query: 86  TLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDE 145
           +LRL  +  G    R+ GH +++  V + +    + S SRDKTIK+W       ++++D 
Sbjct: 4   SLRLSKM--GRLEDRWTGHDREITKVCYGASCNGMFSASRDKTIKMWQRGN--SHSIRDF 171

Query: 146 -SHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNL-ANCKLKTNHIGHTGYLNTVTVSPD 203
             H   V+ +    N+ N ++ S   D  V++W++     L+ N+I     +  V   P 
Sbjct: 172 IGHDMVVTAIHL--NTDNTLLCSGSRDNTVRIWDVETGACLRQNNIPQN-LVTDVKWLPG 342

Query: 204 GSLCASGGKDGQAMLWDLNEGKHLYTLDGGDIINALCFSPNRYWLC-------AATGPSI 256
             L    G+D +  ++D      + +      I   C        C          G   
Sbjct: 343 SHLIIQAGEDKEVRIYDSRTLGIVRSFTKKQYIQMSCDVTADGQFCLTCSNGFGGNGCEA 522

Query: 257 KIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFAGYTDNLVRVWQV 312
            +W L    I +E K        +     C  L  + D   +     D  VRVW +
Sbjct: 523 TLWQLSDGSIQNEFK------GHREAIEACLFLPSNQDMTLIATASRDCSVRVWNM 672
>30256
          Length = 961

 Score = 71.2 bits (173), Expect = 5e-13,   Method: Compositional matrix adjust.
 Identities = 68/229 (29%), Positives = 106/229 (46%), Gaps = 5/229 (2%)
 Frame = +3

Query: 10  TLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDV 69
           TL GH+  V  ++ + +    ++S SRD T+ +W     +   G     L GH   V   
Sbjct: 147 TLYGHSSTVRCLSLSGK---KVVSGSRDATLRVW-----DIESGHCLNVLLGHMAAVR-- 296

Query: 70  VISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTI 129
            +  DG+  +SG+ D T+R+WD  T +      GHT  V S+ F  D   +VSGS D +I
Sbjct: 297 CVQYDGKRVVSGAXDYTVRVWDPDTASCLHTLQGHTNRVYSLQF--DGVYVVSGSLDTSI 470

Query: 130 KLWNT-LGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNH 188
           ++W+   G   +T+    H    S +    N    ++VS   D  VKVW++   K     
Sbjct: 471 RVWDVRCGKLVHTLM--GHQSLTSGLELKDN----LLVSGNADSTVKVWDVHTGKCLQTL 632

Query: 189 IGHTGYLNTVT-VSPDGSLCASGGKDGQAMLWDLNEG---KHLYTLDGG 233
           +G   + + VT +  +     +   DG   LWDLN G   ++L TL  G
Sbjct: 633 LGPNKHRSAVTCLQFNKKFVVTCSDDGTVKLWDLNTGDFIRNLITLPSG 779

 Score = 67.0 bits (162), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 52/189 (27%), Positives = 88/189 (46%), Gaps = 1/189 (0%)
 Frame = +3

Query: 75  GQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNT 134
           G   +SGS D +L++W+  TG  T    GH+  V  ++ S   +++VSGSRD T+++W+ 
Sbjct: 72  GNTVISGSTDRSLKVWNADTGVCTHTLYGHSSTVRCLSLSG--KKVVSGSRDATLRVWDI 245

Query: 135 L-GVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHTG 193
             G C   +    H   V CV++        +VS   D  V+VW+           GHT 
Sbjct: 246 ESGHCLNVLL--GHMAAVRCVQYDGKR----VVSGAXDYTVRVWDPDTASCLHTLQGHTN 407

Query: 194 YLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDIINALCFSPNRYWLCAATG 253
            +   ++  DG    SG  D    +WD+  GK ++TL G   + +     +   +     
Sbjct: 408 RV--YSLQFDGVYVVSGSLDTSIRVWDVRCGKLVHTLMGHQSLTSGLELKDNLLVSGNAD 581

Query: 254 PSIKIWDLE 262
            ++K+WD+ 
Sbjct: 582 STVKVWDVH 608

 Score = 30.4 bits (67), Expect = 0.89,   Method: Compositional matrix adjust.
 Identities = 30/125 (24%), Positives = 56/125 (44%), Gaps = 1/125 (0%)
 Frame = +3

Query: 187 NHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDG-GDIINALCFSPNR 245
           N IGHTG + +  ++  G+   SG  D    +W+ + G   +TL G    +  L  S  +
Sbjct: 27  NLIGHTGGVWSSQMT--GNTVISGSTDRSLKVWNADTGVCTHTLYGHSSTVRCLSLSGKK 200

Query: 246 YWLCAATGPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFAGYTDN 305
             +  +   ++++WD+E    ++ L   + +        +C       DG+ + +G  D 
Sbjct: 201 V-VSGSRDATLRVWDIESGHCLNVLLGHMAAV-------RCVQY----DGKRVVSGAXDY 344

Query: 306 LVRVW 310
            VRVW
Sbjct: 345 TVRVW 359
>19949
          Length = 903

 Score = 67.8 bits (164), Expect = 5e-12,   Method: Compositional matrix adjust.
 Identities = 43/139 (30%), Positives = 65/139 (46%)
 Frame = +2

Query: 75  GQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNT 134
           G +  SGS D  ++LWD+        + GHT  V  + FS D R I S S D  +KLW+ 
Sbjct: 29  GAYTASGSMDCNVKLWDIRRKGCIYTYKGHTGCVCCLRFSPDGRWIASASEDGLVKLWD- 205

Query: 135 LGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHTGY 194
           L   K     + H + V+ + F P+    ++ S   D+ VK W+L   +L +        
Sbjct: 206 LTAGKLLTDLKLHRDAVNTIEFHPHEF--LLASGSADRTVKFWDLETFQLISTTEPEANS 379

Query: 195 LNTVTVSPDGSLCASGGKD 213
           + ++   PDG    SG KD
Sbjct: 380 IRSILFHPDGVCLYSGSKD 436

 Score = 67.0 bits (162), Expect = 9e-12,   Method: Compositional matrix adjust.
 Identities = 51/163 (31%), Positives = 77/163 (47%), Gaps = 2/163 (1%)
 Frame = +2

Query: 108 VLSVAFSSDNRQIVSGSRDKTIKLWNTLGV-CKYTVQDESHSEWVSCVRFSPNSSNPIIV 166
           V S+ F        SGS D  +KLW+     C YT +   H+  V C+RFSP+     I 
Sbjct: 2   VKSLDFHPYGAYTASGSMDCNVKLWDIRRKGCIYTYK--GHTGCVCCLRFSPDGR--WIA 169

Query: 167 SCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKH 226
           S   D LVK+W+L   KL T+   H   +NT+   P   L ASG  D     WDL   + 
Sbjct: 170 SASEDGLVKLWDLTAGKLLTDLKLHRDAVNTIEFHPHEFLLASGSADRTVKFWDLETFQL 349

Query: 227 LYTLDG-GDIINALCFSPNRYWLCAATGPSIKIWDLEGKIIVD 268
           + T +   + I ++ F P+   L + +  ++K++  E   + D
Sbjct: 350 ISTTEPEANSIRSILFHPDGVCLYSGSKDTLKVYHWEPLELYD 478

 Score = 64.3 bits (155), Expect = 6e-11,   Method: Compositional matrix adjust.
 Identities = 44/135 (32%), Positives = 67/135 (49%), Gaps = 2/135 (1%)
 Frame = +2

Query: 174 VKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLD-G 232
           VK+W++        + GHTG +  +  SPDG   AS  +DG   LWDL  GK L  L   
Sbjct: 65  VKLWDIRRKGCIYTYKGHTGCVCCLRFSPDGRWIASASEDGLVKLWDLTAGKLLTDLKLH 244

Query: 233 GDIINALCFSPNRYWLCAATGP-SIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAW 291
            D +N + F P+ + L + +   ++K WDLE          ++IST ++ E     S+ +
Sbjct: 245 RDAVNTIEFHPHEFLLASGSADRTVKFWDLE--------TFQLIST-TEPEANSIRSILF 397

Query: 292 SADGQTLFAGYTDNL 306
             DG  L++G  D L
Sbjct: 398 HPDGVCLYSGSKDTL 442

 Score = 53.5 bits (127), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 36/127 (28%), Positives = 57/127 (44%)
 Frame = +2

Query: 33  SASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDL 92
           S S D  + +W + R    Y       +GH+  V  +  S DG++  S S DG ++LWDL
Sbjct: 44  SGSMDCNVKLWDIRRKGCIY-----TYKGHTGCVCCLRFSPDGRWIASASEDGLVKLWDL 208

Query: 93  TTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVS 152
           T G        H   V ++ F      + SGS D+T+K W+ L   +     E  +  + 
Sbjct: 209 TAGKLLTDLKLHRDAVNTIEFHPHEFLLASGSADRTVKFWD-LETFQLISTTEPEANSIR 385

Query: 153 CVRFSPN 159
            + F P+
Sbjct: 386 SILFHPD 406

 Score = 42.4 bits (98), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 37/124 (29%), Positives = 54/124 (43%)
 Frame = +2

Query: 10  TLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDV 69
           T KGH G V  +  +P     I SAS D  + +W LT      G     L+ H   V+ +
Sbjct: 104 TYKGHTGCVCCLRFSPD-GRWIASASEDGLVKLWDLTA-----GKLLTDLKLHRDAVNTI 265

Query: 70  VISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTI 129
                     SGS D T++ WDL T             + S+ F  D   + SGS+D T+
Sbjct: 266 EFHPHEFLLASGSADRTVKFWDLETFQLISTTEPEANSIRSILFHPDGVCLYSGSKD-TL 442

Query: 130 KLWN 133
           K+++
Sbjct: 443 KVYH 454
>27465
          Length = 658

 Score = 66.2 bits (160), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 37/125 (29%), Positives = 71/125 (56%), Gaps = 2/125 (1%)
 Frame = -1

Query: 57  RALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSD 116
           + LR H   +++V  +  G   ++GS+D T ++WD  +        GH   V ++AF++ 
Sbjct: 379 KVLRAHILPLTNVAFNKSGSSFITGSYDRTCKIWDTASAEELHTLEGHRNVVYAIAFNNP 200

Query: 117 -NRQIVSGSRDKTIKLWNTL-GVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLV 174
              ++++GS DKT KLW+T  G C +T++   H+  + CV F+P+S+  +I +   D   
Sbjct: 199 FGDKVITGSFDKTCKLWSTADGKCYHTLR--GHTAEIVCVSFNPSST--LIATGSMDTTC 32

Query: 175 KVWNL 179
           ++W++
Sbjct: 31  RLWDV 17

 Score = 57.0 bits (136), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 34/123 (27%), Positives = 60/123 (48%)
 Frame = -1

Query: 103 GHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSN 162
            H   + +VAF+      ++GS D+T K+W+T    +     E H   V  + F+ N   
Sbjct: 367 AHILPLTNVAFNKSGSSFITGSYDRTCKIWDTASAEELHTL-EGHRNVVYAIAFN-NPFG 194

Query: 163 PIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLN 222
             +++  +DK  K+W+ A+ K      GHT  +  V+ +P  +L A+G  D    LWD+ 
Sbjct: 193 DKVITGSFDKTCKLWSTADGKCYHTLRGHTAEIVCVSFNPSSTLIATGSMDTTCRLWDVE 14

Query: 223 EGK 225
           + +
Sbjct: 13  KAQ 5

 Score = 51.2 bits (121), Expect = 6e-07,   Method: Compositional matrix adjust.
 Identities = 35/131 (26%), Positives = 59/131 (45%), Gaps = 1/131 (0%)
 Frame = -1

Query: 4   QMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHS 63
              L   L+ H   +T +A        I + S D+T  +W     E  +      L GH 
Sbjct: 394 HFYLFKVLRAHILPLTNVAFNKSGSSFI-TGSYDRTCKIWDTASAEELH-----TLEGHR 233

Query: 64  HFVSDVVISSD-GQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVS 122
           + V  +  ++  G   ++GS+D T +LW    G       GHT +++ V+F+  +  I +
Sbjct: 232 NVVYAIAFNNPFGDKVITGSFDKTCKLWSTADGKCYHTLRGHTAEIVCVSFNPSSTLIAT 53

Query: 123 GSRDKTIKLWN 133
           GS D T +LW+
Sbjct: 52  GSMDTTCRLWD 20

 Score = 45.8 bits (107), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 29/83 (34%), Positives = 39/83 (46%)
 Frame = -1

Query: 10  TLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDV 69
           TL+GH   V  IA    F D +++ S DKT  +W      T  G     LRGH+  +  V
Sbjct: 250 TLEGHRNVVYAIAFNNPFGDKVITGSFDKTCKLW-----STADGKCYHTLRGHTAEIVCV 86

Query: 70  VISSDGQFALSGSWDGTLRLWDL 92
             +       +GS D T RLWD+
Sbjct: 85  SFNPSSTLIATGSMDTTCRLWDV 17

 Score = 40.8 bits (94), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 38/166 (22%), Positives = 69/166 (41%), Gaps = 12/166 (7%)
 Frame = -1

Query: 109 LSVAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVR--------FSPNS 160
           L V   ++  Q+++ S+ + +K W      K   +D+ H      +R         + N 
Sbjct: 505 LVVQEIAEKEQLITPSKQEHVKNW-CFACRKTRPKDDHHFYLFKVLRAHILPLTNVAFNK 329

Query: 161 SNPIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVS-PDGSLCASGGKDGQAMLW 219
           S    ++  +D+  K+W+ A+ +      GH   +  +  + P G    +G  D    LW
Sbjct: 328 SGSSFITGSYDRTCKIWDTASAEELHTLEGHRNVVYAIAFNNPFGDKVITGSFDKTCKLW 149

Query: 220 DLNEGKHLYTLDGGDIINALCFSPNRYWLCAATGP---SIKIWDLE 262
              +GK  +TL  G     +C S N      ATG    + ++WD+E
Sbjct: 148 STADGKCYHTL-RGHTAEIVCVSFNPSSTLIATGSMDTTCRLWDVE 14
>03387
          Length = 1891

 Score = 65.5 bits (158), Expect = 3e-11,   Method: Compositional matrix adjust.
 Identities = 69/269 (25%), Positives = 116/269 (43%), Gaps = 10/269 (3%)
 Frame = +1

Query: 11  LKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKL--TRDETNYGIPQRALRGHSHFVSD 68
           LKGH      ++  P     +LSAS D TI +W +  T+ E+          GH+  V D
Sbjct: 349 LKGHQKEGYGLSWNPNLNGHLLSASDDHTICLWDINSTQRESRVVDAHTIFTGHTSVVED 528

Query: 69  VV--ISSDGQFALSGSWDGTLRLWDLTTGTTTRR---FVGHTKDVLSVAFSSDNRQIVS- 122
           V   +  +  F  S + D  L +WD  + TT++       HT +V  ++F+  +  I++ 
Sbjct: 529 VAWHLLHESLFG-SVADDQKLMIWDTRSNTTSKPSHVVDAHTAEVNCLSFNPYSEFILAT 705

Query: 123 GSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANC 182
           GS DKT+ LW+   +       ESH + +  V++SP++   I+ S G D+ + VW+L+  
Sbjct: 706 GSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPHNET-ILASSGTDRRLHVWDLSK- 879

Query: 183 KLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDIINALCFS 242
                 IG           P   L   GG   +                    I+   ++
Sbjct: 880 ------IGEEQLPEDAEDGPPELLFIHGGHTAK--------------------ISDFSWN 981

Query: 243 PNRYWL-CAATGPSI-KIWDLEGKIIVDE 269
           PN  W+ C+ +  +I ++W +   I  DE
Sbjct: 982 PNEPWIVCSVSEDNIMQVWQMAENIYSDE 1068
>12574
          Length = 521

 Score = 62.4 bits (150), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 39/110 (35%), Positives = 61/110 (55%), Gaps = 1/110 (0%)
 Frame = +3

Query: 59  LRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNR 118
           L GH+  +S V  S +G +  S S D  +++W    G   +   GH   +  VA+SSD++
Sbjct: 174 LAGHTKALSAVKFSPNGDWLASSSADKLIKIWGAYDGKFEKTIAGHKLGLSDVAWSSDSK 353

Query: 119 QIVSGSRDKTIKLWN-TLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVS 167
            + S S DKT+K+W  + G C  T++   HS +V C  F+P S+  +IVS
Sbjct: 354 LLCSASDDKTLKIWEFSTGKCMKTLK--GHSNYVFCCNFNPQSN--LIVS 491

 Score = 62.0 bits (149), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 40/119 (33%), Positives = 61/119 (51%)
 Frame = +3

Query: 6   TLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHF 65
           TL+ TL GH   ++ +  +P   D + S+S DK I +W         G  ++ + GH   
Sbjct: 159 TLKFTLAGHTKALSAVKFSPN-GDWLASSSADKLIKIWGAYD-----GKFEKTIAGHKLG 320

Query: 66  VSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGS 124
           +SDV  SSD +   S S D TL++W+ +TG   +   GH+  V    F+  +  IVSGS
Sbjct: 321 LSDVAWSSDSKLLCSASDDKTLKIWEFSTGKCMKTLKGHSNYVFCCNFNPQSNLIVSGS 497

 Score = 48.1 bits (113), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 32/98 (32%), Positives = 47/98 (47%), Gaps = 1/98 (1%)
 Frame = +3

Query: 147 HSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSL 206
           H++ +S V+FSPN     + S   DKL+K+W   + K +    GH   L+ V  S D  L
Sbjct: 183 HTKALSAVKFSPN--GDWLASSSADKLIKIWGAYDGKFEKTIAGHKLGLSDVAWSSDSKL 356

Query: 207 CASGGKDGQAMLWDLNEGKHLYTLDGGDIINALC-FSP 243
             S   D    +W+ + GK + TL G       C F+P
Sbjct: 357 LCSASDDKTLKIWEFSTGKCMKTLKGHSNYVFCCNFNP 470

 Score = 47.0 bits (110), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 41/141 (29%), Positives = 66/141 (46%), Gaps = 2/141 (1%)
 Frame = +3

Query: 72  SSDGQFALSGSWDGTLRLWDLTTGTTTRRF--VGHTKDVLSVAFSSDNRQIVSGSRDKTI 129
           ++DG+ A + +  GT +       T T +F   GHTK + +V FS +   + S S DK I
Sbjct: 84  TADGKHAPASATSGT-KSSATQKPTYTLKFTLAGHTKALSAVKFSPNGDWLASSSADKLI 260

Query: 130 KLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHI 189
           K+W      K+      H   +S V +S +S   ++ S   DK +K+W  +  K      
Sbjct: 261 KIWGAYDG-KFEKTIAGHKLGLSDVAWSSDS--KLLCSASDDKTLKIWEFSTGKCMKTLK 431

Query: 190 GHTGYLNTVTVSPDGSLCASG 210
           GH+ Y+     +P  +L  SG
Sbjct: 432 GHSNYVFCCNFNPQSNLIVSG 494

 Score = 37.7 bits (86), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 27/90 (30%), Positives = 44/90 (48%), Gaps = 2/90 (2%)
 Frame = +3

Query: 184 LKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDI-INALCFS 242
           LK    GHT  L+ V  SP+G   AS   D    +W   +GK   T+ G  + ++ + +S
Sbjct: 162 LKFTLAGHTKALSAVKFSPNGDWLASSSADKLIKIWGAYDGKFEKTIAGHKLGLSDVAWS 341

Query: 243 PNRYWLCAAT-GPSIKIWDLEGKIIVDELK 271
            +   LC+A+   ++KIW+      +  LK
Sbjct: 342 SDSKLLCSASDDKTLKIWEFSTGKCMKTLK 431

 Score = 32.7 bits (73), Expect = 0.19,   Method: Compositional matrix adjust.
 Identities = 25/91 (27%), Positives = 46/91 (50%), Gaps = 3/91 (3%)
 Frame = +3

Query: 228 YTLDGG-DIINALCFSPNRYWLCAATGPS-IKIWD-LEGKIIVDELKQEVISTSSKAEPP 284
           +TL G    ++A+ FSPN  WL +++    IKIW   +GK       ++ I+        
Sbjct: 168 FTLAGHTKALSAVKFSPNGDWLASSSADKLIKIWGAYDGKF------EKTIA----GHKL 317

Query: 285 QCTSLAWSADGQTLFAGYTDNLVRVWQVTIG 315
             + +AWS+D + L +   D  +++W+ + G
Sbjct: 318 GLSDVAWSSDSKLLCSASDDKTLKIWEFSTG 410
>17602
          Length = 481

 Score = 62.0 bits (149), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 46/155 (29%), Positives = 72/155 (46%), Gaps = 4/155 (2%)
 Frame = +3

Query: 88  RLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTL-GVCKYTVQDES 146
           R+WD+ TG   +    H+  V +V F+ D   IVS S D   ++W+T  G C  T+ D+ 
Sbjct: 3   RIWDVKTGKCLKTLPAHSDPVTAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLXTLIDDD 182

Query: 147 HSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVS---PD 203
           +   VS V+FSPN     I++   D  +K+W+ +  K    ++GH      +  +     
Sbjct: 183 NPP-VSFVKFSPNGK--YILAATLDNTLKLWDYSKGKCLKTYVGHRNEKYCIFANFSVTG 353

Query: 204 GSLCASGGKDGQAMLWDLNEGKHLYTLDGGDIINA 238
           G    SG +D    +W+L        LD GD   A
Sbjct: 354 GKWIVSGSEDNMVYIWNL--------LDQGDSTEA 434

 Score = 55.5 bits (132), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 38/125 (30%), Positives = 61/125 (48%), Gaps = 2/125 (1%)
 Frame = +3

Query: 57  RALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLS-VAFSS 115
           + L  HS  V+ V  + DG   +S S+DG  R+WD  +G      +      +S V FS 
Sbjct: 36  KTLPAHSDPVTAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLXTLIDDDNPPVSFVKFSP 215

Query: 116 DNRQIVSGSRDKTIKLWN-TLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLV 174
           + + I++ + D T+KLW+ + G C  T     + ++     FS  +    IVS   D +V
Sbjct: 216 NGKYILAATLDNTLKLWDYSKGKCLKTYVGHRNEKYCIFANFSV-TGGKWIVSGSEDNMV 392

Query: 175 KVWNL 179
            +WNL
Sbjct: 393 YIWNL 407

 Score = 49.3 bits (116), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 28/73 (38%), Positives = 42/73 (57%), Gaps = 3/73 (4%)
 Frame = +3

Query: 66  VSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGH--TKDVLSVAFS-SDNRQIVS 122
           VS V  S +G++ L+ + D TL+LWD + G   + +VGH   K  +   FS +  + IVS
Sbjct: 192 VSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYVGHRNEKYCIFANFSVTGGKWIVS 371

Query: 123 GSRDKTIKLWNTL 135
           GS D  + +WN L
Sbjct: 372 GSEDNMVYIWNLL 410

 Score = 48.1 bits (113), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 42/143 (29%), Positives = 67/143 (46%), Gaps = 5/143 (3%)
 Frame = +3

Query: 175 KVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTL--DG 232
           ++W++   K       H+  +  V  + DGSL  S   DG   +WD   G+ L TL  D 
Sbjct: 3   RIWDVKTGKCLKTLPAHSDPVTAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLXTLIDDD 182

Query: 233 GDIINALCFSPN-RYWLCAATGPSIKIWDL-EGKIIVDELKQEVISTSSKAEPPQCTSLA 290
              ++ + FSPN +Y L A    ++K+WD  +GK     LK  V   + K     C    
Sbjct: 183 NPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKC----LKTYVGHRNEK----YCIFAN 338

Query: 291 WSA-DGQTLFAGYTDNLVRVWQV 312
           +S   G+ + +G  DN+V +W +
Sbjct: 339 FSVTGGKWIVSGSEDNMVYIWNL 407
>03395
          Length = 2795

 Score = 60.8 bits (146), Expect = 7e-10,   Method: Compositional matrix adjust.
 Identities = 58/222 (26%), Positives = 100/222 (45%), Gaps = 11/222 (4%)
 Frame = +2

Query: 66  VSDVVISSDGQFALSGSWDGTLRLWDLT----TGTTTRRFVGHTKD----VLSVAFSSDN 117
           V+ + ++S G   +SG  +G +R+WD+     TG T    V + K+    V ++   +++
Sbjct: 5   VTAIAVTSCGTKLVSGGGEGQVRVWDIVKDMLTGKTRGDLVANMKEHKGKVTAIQIHTND 184

Query: 118 RQIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVW 177
           R  VS S D +  +W+   +     Q    +    CV F     +  I++ G D  +  W
Sbjct: 185 RCCVSASTDGSTIIWDL--ITNTRSQIVLANTLFKCVCFGGKDLH--ILTSGTDHKIGYW 352

Query: 178 NLANCKLKTNHIG-HTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDG-GDI 235
            + +  L     G  TG +NT+ +  DG    +GG+D    LW  NEG+  +T  G  + 
Sbjct: 353 EVGDGGLLRELEGSQTGAINTIDIDRDGQTILTGGEDSLLKLWRYNEGEVTHTGIGHSNQ 532

Query: 236 INALCFSPNRYWLCA-ATGPSIKIWDLEGKIIVDELKQEVIS 276
           I      PNR+++ +     ++ IW       VD L +  IS
Sbjct: 533 ITKARICPNRHYIVSGGEDGALHIWKFPDGC*VDCLPRHGIS 658

 Score = 53.5 bits (127), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 46/210 (21%), Positives = 89/210 (42%), Gaps = 3/210 (1%)
 Frame = +2

Query: 18  VTQIATTPQFPDMILSASRDKTIIMWKLTRD---ETNYGIPQRALRGHSHFVSDVVISSD 74
           VT IA T     ++ S   +  + +W + +D       G     ++ H   V+ + I ++
Sbjct: 5   VTAIAVTSCGTKLV-SGGGEGQVRVWDIVKDMLTGKTRGDLVANMKEHKGKVTAIQIHTN 181

Query: 75  GQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNT 134
            +  +S S DG+  +WDL T T ++  + +T     V F   +  I++   D  I  W  
Sbjct: 182 DRCCVSASTDGSTIIWDLITNTRSQIVLANTL-FKCVCFGGKDLHILTSGTDHKIGYWEV 358

Query: 135 LGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHTGY 194
                    + S +  ++ +    +     I++ G D L+K+W     ++    IGH+  
Sbjct: 359 GDGGLLRELEGSQTGAINTIDIDRDGQT--ILTGGEDSLLKLWRYNEGEVTHTGIGHSNQ 532

Query: 195 LNTVTVSPDGSLCASGGKDGQAMLWDLNEG 224
           +    + P+     SGG+DG   +W   +G
Sbjct: 533 ITKARICPNRHYIVSGGEDGALHIWKFPDG 622

 Score = 45.4 bits (106), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 35/169 (20%), Positives = 68/169 (40%), Gaps = 9/169 (5%)
 Frame = +2

Query: 156 FSPNSSNPIIVSCGWDKLVKVWNLAN--------CKLKTNHIGHTGYLNTVTVSPDGSLC 207
            +  S    +VS G +  V+VW++            L  N   H G +  + +  +   C
Sbjct: 14  IAVTSCGTKLVSGGGEGQVRVWDIVKDMLTGKTRGDLVANMKEHKGKVTAIQIHTNDRCC 193

Query: 208 ASGGKDGQAMLWDLNEGKHLYTLDGGDIINALCFS-PNRYWLCAATGPSIKIWDLEGKII 266
            S   DG  ++WDL        +    +   +CF   + + L + T   I  W++    +
Sbjct: 194 VSASTDGSTIIWDLITNTRSQIVLANTLFKCVCFGGKDLHILTSGTDHKIGYWEVGDGGL 373

Query: 267 VDELKQEVISTSSKAEPPQCTSLAWSADGQTLFAGYTDNLVRVWQVTIG 315
           + EL+         ++     ++    DGQT+  G  D+L+++W+   G
Sbjct: 374 LRELE--------GSQTGAINTIDIDRDGQTILTGGEDSLLKLWRYNEG 496
>18981
          Length = 407

 Score = 59.3 bits (142), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 38/106 (35%), Positives = 57/106 (53%)
 Frame = -2

Query: 27  FPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVISSDGQFALSGSWDGT 86
             +MI+SA+ D+T+ +W L             LRGH+  V  V I   G+  +SGSWD T
Sbjct: 391 LDNMIISAATDRTLRVWCLKNT-----CLLHTLRGHNDDVECVCIY--GRRVVSGSWDKT 233

Query: 87  LRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLW 132
           L +W++ TG    +  GHT+ + +V F  D  + VSGS D  ++ W
Sbjct: 232 LIVWEVDTGRPVHQLHGHTEAITAVQF--DEGKAVSGSADGDVRTW 101

 Score = 45.1 bits (105), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 37/135 (27%), Positives = 59/135 (43%), Gaps = 1/135 (0%)
 Frame = -2

Query: 117 NRQIVSGSRDKTIKLWNTLGVC-KYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVK 175
           +  I+S + D+T+++W     C  +T++   H++ V CV          +VS  WDK + 
Sbjct: 388 DNMIISAATDRTLRVWCLKNTCLLHTLR--GHNDDVECVCIYGRR----VVSGSWDKTLI 227

Query: 176 VWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDI 235
           VW +   +      GHT  +  V    D     SG  DG    W L+ G+ L T+  G  
Sbjct: 226 VWEVDTGRPVHQLHGHTEAITAVQF--DEGKAVSGSADGDVRTWALDTGQCLLTMTTGQD 53

Query: 236 INALCFSPNRYWLCA 250
           I   C   N+  + A
Sbjct: 52  IEVYCVVYNQEVIAA 8

 Score = 32.3 bits (72), Expect = 0.25,   Method: Compositional matrix adjust.
 Identities = 26/102 (25%), Positives = 49/102 (48%), Gaps = 1/102 (0%)
 Frame = -2

Query: 162 NPIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDL 221
           + +I+S   D+ ++VW L N  L     GH   +  V +   G    SG  D   ++W++
Sbjct: 388 DNMIISAATDRTLRVWCLKNTCLLHTLRGHNDDVECVCIY--GRRVVSGSWDKTLIVWEV 215

Query: 222 NEGKHLYTLDGG-DIINALCFSPNRYWLCAATGPSIKIWDLE 262
           + G+ ++ L G  + I A+ F   +    +A G  ++ W L+
Sbjct: 214 DTGRPVHQLHGHTEAITAVQFDEGKAVSGSADG-DVRTWALD 92
>12960
          Length = 550

 Score = 57.4 bits (137), Expect = 8e-09,   Method: Compositional matrix adjust.
 Identities = 49/177 (27%), Positives = 83/177 (46%), Gaps = 9/177 (5%)
 Frame = +2

Query: 11  LKGHNGWVTQIATTPQFPDMILSA-----SRDKTIIMWKLT-RDETNYGIPQRALRGHSH 64
           LK     + ++   PQ P+ +LS      S   T + ++L  R E      Q+A+R    
Sbjct: 23  LKTKPATLERLVGLPQ-PN*VLSVFNKTHSVQNTNMKFELPDRKEVTINCKQQAVRA--- 190

Query: 65  FVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGS 124
               V  S D ++ ++   D +++LW+       + ++GH  +VL    S DN QI SG 
Sbjct: 191 ----VRFSVDSRYCMTCGSDKSVKLWNPHRELFLKTYIGHGHEVLDAQGSGDNSQICSGG 358

Query: 125 RDKTIKLWNTL---GVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWN 178
            DKT+ L++      + KY      H+  V+CV+F  N  + +I+S   D  V+ W+
Sbjct: 359 IDKTVVLFDVASGQALRKY----RDHAGTVNCVKF--NEESTVILSGSLDNTVRAWD 511

 Score = 52.8 bits (125), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 31/103 (30%), Positives = 52/103 (50%)
 Frame = +2

Query: 32  LSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWD 91
           ++   DK++ +W   R+     +  +   GH H V D   S D     SG  D T+ L+D
Sbjct: 221 MTCGSDKSVKLWNPHRE-----LFLKTYIGHGHEVLDAQGSGDNSQICSGGIDKTVVLFD 385

Query: 92  LTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNT 134
           + +G   R++  H   V  V F+ ++  I+SGS D T++ W+T
Sbjct: 386 VASGQALRKYRDHAGTVNCVKFNEESTVILSGSLDNTVRAWDT 514

 Score = 43.9 bits (102), Expect = 8e-05,   Method: Compositional matrix adjust.
 Identities = 34/118 (28%), Positives = 53/118 (44%), Gaps = 2/118 (1%)
 Frame = +2

Query: 149 EWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCA 208
           + V  VRFS +S     ++CG DK VK+WN         +IGH   +     S D S   
Sbjct: 176 QAVRAVRFSVDSR--YCMTCGSDKSVKLWNPHRELFLKTYIGHGHEVLDAQGSGDNSQIC 349

Query: 209 SGGKDGQAMLWDLNEGKHLYTL-DGGDIINALCFSPNR-YWLCAATGPSIKIWDLEGK 264
           SGG D   +L+D+  G+ L    D    +N + F+      L  +   +++ WD   +
Sbjct: 350 SGGIDKTVVLFDVASGQALRKYRDHAGTVNCVKFNEESTVILSGSLDNTVRAWDTRSR 523

 Score = 42.0 bits (97), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 35/122 (28%), Positives = 57/122 (46%), Gaps = 3/122 (2%)
 Frame = +2

Query: 108 VLSVAFSSDNRQIVSGSRDKTIKLWN---TLGVCKYTVQDESHSEWVSCVRFSPNSSNPI 164
           V +V FS D+R  ++   DK++KLWN    L +  Y      H   V   + S ++S   
Sbjct: 182 VRAVRFSVDSRYCMTCGSDKSVKLWNPHRELFLKTYI----GHGHEVLDAQGSGDNSQ-- 343

Query: 165 IVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEG 224
           I S G DK V ++++A+ +    +  H G +N V  + + ++  SG  D     WD    
Sbjct: 344 ICSGGIDKTVVLFDVASGQALRKYRDHAGTVNCVKFNEESTVILSGSLDNTVRAWDTRSR 523

Query: 225 KH 226
            H
Sbjct: 524 SH 529

 Score = 33.5 bits (75), Expect = 0.11,   Method: Compositional matrix adjust.
 Identities = 21/69 (30%), Positives = 33/69 (47%)
 Frame = +2

Query: 30  MILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVISSDGQFALSGSWDGTLRL 89
            I S   DKT++++ +       G   R  R H+  V+ V  + +    LSGS D T+R 
Sbjct: 341 QICSGGIDKTVVLFDVAS-----GQALRKYRDHAGTVNCVKFNEESTVILSGSLDNTVRA 505

Query: 90  WDLTTGTTT 98
           WD  + + T
Sbjct: 506 WDTRSRSHT 532
>02090
          Length = 1841

 Score = 56.6 bits (135), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 36/121 (29%), Positives = 55/121 (45%)
 Frame = -3

Query: 128  TIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTN 187
            T+ +W+ L      ++ E  S   +C   + +    +  SC  D  + VW+L N  L   
Sbjct: 1689 TLSIWD-LATPTPRIKAELTSSAPACYALAISPDGKVCFSCCSDGNIAVWDLHNQTLVRQ 1513

Query: 188  HIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDIINALCFSPNRYW 247
              GHT   + + +SPDG+   +GG D     WDL EG+ L   D    I +L + P   W
Sbjct: 1512 FQGHTDGASCIDISPDGTKLWTGGLDNTVRSWDLREGRQLQQHDFSSQIFSLGYCPTGEW 1333

Query: 248  L 248
            L
Sbjct: 1332 L 1330

 Score = 47.0 bits (110), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 22/65 (33%), Positives = 34/65 (52%)
 Frame = -3

Query: 69   VVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKT 128
            + IS DG+   S   DG + +WDL   T  R+F GHT     +  S D  ++ +G  D T
Sbjct: 1608 LAISPDGKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISPDGTKLWTGGLDNT 1429

Query: 129  IKLWN 133
            ++ W+
Sbjct: 1428 VRSWD 1414

 Score = 36.2 bits (82), Expect = 0.017,   Method: Compositional matrix adjust.
 Identities = 39/154 (25%), Positives = 60/154 (38%), Gaps = 4/154 (2%)
 Frame = -3

Query: 28   PD--MILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVISSDGQFALSGSWDG 85
            PD  +  S   D  I +W L           R  +GH+   S + IS DG    +G  D 
Sbjct: 1596 PDGKVCFSCCSDGNIAVWDLHNQTL-----VRQFQGHTDGASCIDISPDGTKLWTGGLDN 1432

Query: 86   TLRLWDLTTGTTTRRFVGH--TKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQ 143
            T+R WDL  G   R+   H  +  + S+ +      +  G     +++ +     KY  Q
Sbjct: 1431 TVRSWDLREG---RQLQQHDFSSQIFSLGYCPTGEWLAVGMESSNVEVLHHSKPDKY--Q 1267

Query: 144  DESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVW 177
               H   V  ++F+        VS G D L+  W
Sbjct: 1266 LHLHESCVLSLKFA--YCGKWFVSTGKDNLLNAW 1171

 Score = 31.2 bits (69), Expect = 0.65,   Method: Compositional matrix adjust.
 Identities = 18/58 (31%), Positives = 30/58 (51%)
 Frame = -3

Query: 255  SIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFAGYTDNLVRVWQV 312
            ++ IWDL        +K E+ S++     P C +LA S DG+  F+  +D  + VW +
Sbjct: 1689 TLSIWDLATP--TPRIKAELTSSA-----PACYALAISPDGKVCFSCCSDGNIAVWDL 1537
>02960
          Length = 1577

 Score = 53.1 bits (126), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 65/270 (24%), Positives = 110/270 (40%), Gaps = 38/270 (14%)
 Frame = +2

Query: 79  LSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAF-----SSDNRQIVSGSRDKTIKLW- 132
           LSGS+D T+RLW  T G       GHT  V  VA+     SS     V+GS D+T  +W 
Sbjct: 527 LSGSYDNTVRLWS-TKGEAIMTIPGHTSPVKCVAWIKHDESSGVSTFVTGSHDQTALVWQ 703

Query: 133 ---NTLGV-CKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNH 188
               T  V C+ + +   H+  V CV  SP+S    + +  WDK++K+W+  +C +  + 
Sbjct: 704 WQRETNEVDCRLSCR--GHAASVDCVAVSPDSQQ--MCTGSWDKMLKLWS-TDCNVDGDQ 868

Query: 189 IGHT------------------------GYLNTVTVSP--DGSLCASGGKDGQAMLWDLN 222
              T                        G+   V+     D     +   D    LWDL+
Sbjct: 869 SEDTERPSKKKKSAKSTTQTRVPVLTLSGHAEAVSAVRWLDPHRVVTSSWDHSLRLWDLH 1048

Query: 223 EGKHLYTLDGGDIINALCFSPNRYWLCAATGPSIKIWDLEGKIIVDELKQ-EVISTSSKA 281
             +    + G   +  + +SP  + L   +       D   +++     + E +  +  +
Sbjct: 1049TAQQTSLIQGSKAVLDVAYSPLSHMLITGSA------DRHVRLVDPRCSEGETVKCAFTS 1210

Query: 282 EPPQCTSLAWSADGQTLF-AGYTDNLVRVW 310
                T + WS   + LF +G  DN++++W
Sbjct: 1211HTGWVTGVDWSPTREHLFLSGSYDNVLKLW 1300

 Score = 51.6 bits (122), Expect = 4e-07,   Method: Compositional matrix adjust.
 Identities = 64/229 (27%), Positives = 101/229 (44%), Gaps = 34/229 (14%)
 Frame = +2

Query: 31  ILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVISSDGQFALSGSWDGTLRLW 90
            ++ S D+T ++W+  R ETN    + + RGH+  V  V +S D Q   +GSWD  L+LW
Sbjct: 662 FVTGSHDQTALVWQWQR-ETNEVDCRLSCRGHAASVDCVAVSPDSQQMCTGSWDKMLKLW 838

Query: 91  D----------------------LTTGTTTRRFV----GHTKDVLSVAFSSDNRQIVSGS 124
                                    + T TR  V    GH + V +V +  D  ++V+ S
Sbjct: 839 STDCNVDGDQSEDTERPSKKKKSAKSTTQTRVPVLTLSGHAEAVSAVRW-LDPHRVVTSS 1015

Query: 125 RDKTIKLWNTLGVCKYTVQDES---HSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLAN 181
            D +++LW+      +T Q  S    S+ V  V +SP S   ++++   D+ V++ +   
Sbjct: 1016WDHSLRLWDL-----HTAQQTSLIQGSKAVLDVAYSPLSH--MLITGSADRHVRLVD-PR 1171

Query: 182 CK----LKTNHIGHTGYLNTVTVSPDGS-LCASGGKDGQAMLWDLNEGK 225
           C     +K     HTG++  V  SP    L  SG  D    LWD    K
Sbjct: 1172CSEGETVKCAFTSHTGWVTGVDWSPTREHLFLSGSYDNVLKLWDTRSPK 1318

 Score = 30.0 bits (66), Expect = 1.4,   Method: Compositional matrix adjust.
 Identities = 13/42 (30%), Positives = 21/42 (50%)
 Frame = +2

Query: 2    TEQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMW 43
            +E  T++     H GWVT +  +P    + LS S D  + +W
Sbjct: 1175 SEGETVKCAFTSHTGWVTGVDWSPTREHLFLSGSYDNVLKLW 1300
>11493
          Length = 535

 Score = 52.0 bits (123), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 42/170 (24%), Positives = 74/170 (43%), Gaps = 9/170 (5%)
 Frame = -2

Query: 53  GIPQRALR----GHSHFVSDVVISSDGQFALSGSWDGTLRLWDLT-----TGTTTRRFVG 103
           GIP+ A +     H   V  V IS+  ++  +G   G +++WD++        +    + 
Sbjct: 519 GIPRHARQINTLSHGEVVCAVTISNPTKYVYTGG-KGCVKVWDISQPGNKNPVSQLDCLQ 343

Query: 104 HTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNP 163
               + SV    D R ++ G     + +W+ L      ++ E  S   +C   + +  + 
Sbjct: 342 RDNYIRSVKLLPDGRTLIVGGEASNLSIWD-LASPTPRIKAELTSAAPACYALAISPDSK 166

Query: 164 IIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKD 213
           +  SC  D  + VW+L N  L     GHT   + + +SPDGS   +GG D
Sbjct: 165 VCFSCCSDGNIAVWDLHNEILVRQFQGHTDGASCIDISPDGSRLWTGGLD 16

 Score = 40.0 bits (92), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 19/62 (30%), Positives = 30/62 (48%)
 Frame = -2

Query: 69  VVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKT 128
           + IS D +   S   DG + +WDL      R+F GHT     +  S D  ++ +G  D T
Sbjct: 189 LAISPDSKVCFSCCSDGNIAVWDLHNEILVRQFQGHTDGASCIDISPDGSRLWTGGLDNT 10

Query: 129 IK 130
           ++
Sbjct: 9   VR 4

 Score = 38.1 bits (87), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 34/135 (25%), Positives = 57/135 (42%), Gaps = 7/135 (5%)
 Frame = -2

Query: 185 KTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDL------NEGKHLYTLDGGDIINA 238
           + N + H   +  VT+S       +GGK G   +WD+      N    L  L   + I +
Sbjct: 498 QINTLSHGEVVCAVTISNPTKYVYTGGK-GCVKVWDISQPGNKNPVSQLDCLQRDNYIRS 322

Query: 239 LCFSPN-RYWLCAATGPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQT 297
           +   P+ R  +      ++ IWDL        +K E+ S +     P C +LA S D + 
Sbjct: 321 VKLLPDGRTLIVGGEASNLSIWDLASP--TPRIKAELTSAA-----PACYALAISPDSKV 163

Query: 298 LFAGYTDNLVRVWQV 312
            F+  +D  + VW +
Sbjct: 162 CFSCCSDGNIAVWDL 118

 Score = 37.0 bits (84), Expect = 0.009,   Method: Compositional matrix adjust.
 Identities = 26/124 (20%), Positives = 52/124 (41%), Gaps = 2/124 (1%)
 Frame = -2

Query: 40  IIMWKLTRDETNYGIPQRALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTR 99
           + +W +++      + Q       +++  V +  DG+  + G     L +WDL + T   
Sbjct: 408 VKVWDISQPGNKNPVSQLDCLQRDNYIRSVKLLPDGRTLIVGGEASNLSIWDLASPTPRI 229

Query: 100 R--FVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFS 157
           +           ++A S D++   S   D  I +W+ L       Q + H++  SC+  S
Sbjct: 228 KAELTSAAPACYALAISPDSKVCFSCCSDGNIAVWD-LHNEILVRQFQGHTDGASCIDIS 52

Query: 158 PNSS 161
           P+ S
Sbjct: 51  PDGS 40

 Score = 28.9 bits (63), Expect = 2.8,   Method: Compositional matrix adjust.
 Identities = 25/128 (19%), Positives = 53/128 (41%), Gaps = 6/128 (4%)
 Frame = -2

Query: 102 VGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDE----SHSEWVSCVRFS 157
           + H + V +V  S+  + + +G +   +K+W+           +        ++  V+  
Sbjct: 486 LSHGEVVCAVTISNPTKYVYTGGK-GCVKVWDISQPGNKNPVSQLDCLQRDNYIRSVKLL 310

Query: 158 PNSSNPIIVSCGWDKLVKVWNLANC--KLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQ 215
           P+    I+   G    + +W+LA+   ++K            + +SPD  +C S   DG 
Sbjct: 309 PDGRTLIVG--GEASNLSIWDLASPTPRIKAELTSAAPACYALAISPDSKVCFSCCSDGN 136

Query: 216 AMLWDLNE 223
             +WDL+ 
Sbjct: 135 IAVWDLHN 112
>13278
          Length = 870

 Score = 51.2 bits (121), Expect = 5e-07,   Method: Compositional matrix adjust.
 Identities = 23/54 (42%), Positives = 32/54 (59%)
 Frame = +1

Query: 80  SGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWN 133
           S S+D T+RLW++  G        H + V SVAFS D + + SGS DK + +WN
Sbjct: 127 SASFDSTVRLWEVERGLCLHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWN 288

 Score = 47.0 bits (110), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 27/107 (25%), Positives = 53/107 (49%)
 Frame = +1

Query: 23  TTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVISSDGQFALSGS 82
           + P    ++ SAS D T+ +W++ R     G+    L  H   V  V  S DG++  SGS
Sbjct: 97  SNPNTSLILASASFDSTVRLWEVER-----GLCLHTLTKHQEPVYSVAFSPDGKYLASGS 261

Query: 83  WDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTI 129
           +D  + +W++ TG+    + G T  +  V ++    ++ + + D ++
Sbjct: 262 FDKCVHIWNVQTGSLVHSYKG-TGGIFEVCWNHRGDKVGASASDGSV 399

 Score = 40.0 bits (92), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 24/89 (26%), Positives = 41/89 (46%), Gaps = 4/89 (4%)
 Frame = +1

Query: 158 PNSSNP----IIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKD 213
           P +SNP    I+ S  +D  V++W +           H   + +V  SPDG   ASG  D
Sbjct: 88  PGTSNPNTSLILASASFDSTVRLWEVERGLCLHTLTKHQEPVYSVAFSPDGKYLASGSFD 267

Query: 214 GQAMLWDLNEGKHLYTLDGGDIINALCFS 242
               +W++  G  +++  G   I  +C++
Sbjct: 268 KCVHIWNVQTGSLVHSYKGTGGIFEVCWN 354

 Score = 30.8 bits (68), Expect = 0.76,   Method: Compositional matrix adjust.
 Identities = 18/67 (26%), Positives = 34/67 (50%)
 Frame = +1

Query: 250 AATGPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFAGYTDNLVRV 309
           A+   ++++W++E  + +  L +         EP    S+A+S DG+ L +G  D  V +
Sbjct: 130 ASFDSTVRLWEVERGLCLHTLTKH-------QEP--VYSVAFSPDGKYLASGSFDKCVHI 282

Query: 310 WQVTIGT 316
           W V  G+
Sbjct: 283 WNVQTGS 303
>21105
          Length = 650

 Score = 49.7 bits (117), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 32/102 (31%), Positives = 46/102 (45%), Gaps = 3/102 (2%)
 Frame = +1

Query: 79  LSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWN---TL 135
           ++   D  +R +D  TG      V H   V S+A   +   ++SGS D +I+LWN     
Sbjct: 112 ITAHEDRHIRFFDNNTGKLIHAMVAHLDSVTSLAVDPNGLYLLSGSHDCSIRLWNLDSKT 291

Query: 136 GVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVW 177
            V + T   +   E +  V F P    P I S G D L KV+
Sbjct: 292 CVQEITSHRKKFDESIHDVAFHPQ--KPYIASAGADALAKVF 411

 Score = 43.1 bits (100), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 30/112 (26%), Positives = 50/112 (44%), Gaps = 4/112 (3%)
 Frame = +1

Query: 25  PQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVISSDGQFALSGSWD 84
           P  P + ++A  D+ I  +     + N G    A+  H   V+ + +  +G + LSGS D
Sbjct: 94  PTMP-ITITAHEDRHIRFF-----DNNTGKLIHAMVAHLDSVTSLAVDPNGLYLLSGSHD 255

Query: 85  GTLRLWDLTTGTTTRRFVGHTK----DVLSVAFSSDNRQIVSGSRDKTIKLW 132
            ++RLW+L + T  +    H K     +  VAF      I S   D   K++
Sbjct: 256 CSIRLWNLDSKTCVQEITSHRKKFDESIHDVAFHPQKPYIASAGADALAKVF 411

 Score = 34.3 bits (77), Expect = 0.070,   Method: Compositional matrix adjust.
 Identities = 21/96 (21%), Positives = 41/96 (42%), Gaps = 7/96 (7%)
 Frame = +1

Query: 163 PIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLN 222
           PI ++   D+ ++ ++    KL    + H   + ++ V P+G    SG  D    LW+L+
Sbjct: 103 PITITAHEDRHIRFFDNNTGKLIHAMVAHLDSVTSLAVDPNGLYLLSGSHDCSIRLWNLD 282

Query: 223 EG-------KHLYTLDGGDIINALCFSPNRYWLCAA 251
                     H    D    I+ + F P + ++ +A
Sbjct: 283 SKTCVQEITSHRKKFDES--IHDVAFHPQKPYIASA 384
>37180
          Length = 681

 Score = 48.9 bits (115), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 28/77 (36%), Positives = 43/77 (55%), Gaps = 1/77 (1%)
 Frame = +1

Query: 58  ALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLT-TGTTTRRFVGHTKDVLSVAFSSD 116
            L GH   +SDV      +  ++ S D T RLWD   +      F GHT+ V S  F+S 
Sbjct: 4   VLNGHDQELSDVHAHPTQRLVVTSSKDMTFRLWDFRDSALLVNVFQGHTQPVTSAVFASG 183

Query: 117 NRQIVSGSRDKTIKLWN 133
           ++ +VSGS D+T+++W+
Sbjct: 184 DK-VVSGSDDRTVRVWD 231

 Score = 36.6 bits (83), Expect = 0.013,   Method: Compositional matrix adjust.
 Identities = 23/82 (28%), Positives = 44/82 (53%)
 Frame = +1

Query: 11 LKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVV 70
          L GH+  ++ +   P    +++++S+D T  +W    D  +  +     +GH+  V+  V
Sbjct: 7  LNGHDQELSDVHAHPT-QRLVVTSSKDMTFRLW----DFRDSALLVNVFQGHTQPVTSAV 171

Query: 71 ISSDGQFALSGSWDGTLRLWDL 92
           +S G   +SGS D T+R+WD+
Sbjct: 172FAS-GDKVVSGSDDRTVRVWDM 234

 Score = 29.6 bits (65), Expect = 1.7,   Method: Compositional matrix adjust.
 Identities = 16/76 (21%), Positives = 30/76 (39%), Gaps = 2/76 (2%)
 Frame = +1

Query: 190 GHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDI--INALCFSPNRYW 247
           GH   L+ V   P   L  +  KD    LWD  +   L  +  G    + +  F+     
Sbjct: 13  GHDQELSDVHAHPTQRLVVTSSKDMTFRLWDFRDSALLVNVFQGHTQPVTSAVFASGDKV 192

Query: 248 LCAATGPSIKIWDLEG 263
           +  +   ++++WD+  
Sbjct: 193 VSGSDDRTVRVWDMRN 240
>19498
          Length = 903

 Score = 48.1 bits (113), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 48/201 (23%), Positives = 85/201 (42%), Gaps = 30/201 (14%)
 Frame = -1

Query: 40  IIMWKLT-----RDETNYGIPQRALRGHSHF--VSDVVISSDGQFALSGSWDGTLRLWDL 92
           +++W +      ++E +  +P+   +  SH   V+ V  S +G+F  SG  D  + +W +
Sbjct: 876 VVIWNMAPIRDEKEEADDDVPRVLCQMDSHLGCVNCVRWSENGKFLASGGDDKLIMIWQI 697

Query: 93  TTGTTTRR-----------------FVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTL 135
           + G  + +                   GH  DVL +A+S  +  + S S D TI +WN L
Sbjct: 696 SRGFGSGKSFGSNVTILEHWRSVATLRGHAGDVLDLAWSPQDLWLASCSVDNTIVVWNAL 517

Query: 136 GVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKT------NHI 189
              +       H+  V  V + P      + S   DK ++VW  ++ K +T         
Sbjct: 516 KFSEQVAVIRGHAGMVKGVTWDP--VGRYLASQSDDKTLRVWRTSDWKEETCVKSCFKEC 343

Query: 190 GHTGYLNTVTVSPDGSLCASG 210
           G T ++  +  SPDG+   S 
Sbjct: 342 GGTTHVLRLNWSPDGNHVVSA 280

 Score = 47.0 bits (110), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 39/122 (31%), Positives = 58/122 (47%), Gaps = 7/122 (5%)
 Frame = -1

Query: 9   GTLKGHNGWVTQIATTPQFPDMIL-SASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVS 67
            TL+GH G V  +A +PQ  D+ L S S D TI++W   +      +    +RGH+  V 
Sbjct: 627 ATLRGHAGDVLDLAWSPQ--DLWLASCSVDNTIVVWNALKFSEQVAV----IRGHAGMVK 466

Query: 68  DVVISSDGQFALSGSWDGTLRLW------DLTTGTTTRRFVGHTKDVLSVAFSSDNRQIV 121
            V     G++  S S D TLR+W      + T   +  +  G T  VL + +S D   +V
Sbjct: 465 GVTWDPVGRYLASQSDDKTLRVWRTSDWKEETCVKSCFKECGGTTHVLRLNWSPDGNHVV 286

Query: 122 SG 123
           S 
Sbjct: 285 SA 280

 Score = 38.1 bits (87), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 35/143 (24%), Positives = 59/143 (41%), Gaps = 20/143 (13%)
 Frame = -1

Query: 191 HTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEG-----------------KHLYTLDG- 232
           H G +N V  S +G   ASGG D   M+W ++ G                 + + TL G 
Sbjct: 789 HLGCVNCVRWSENGKFLASGGDDKLIMIWQISRGFGSGKSFGSNVTILEHWRSVATLRGH 610

Query: 233 -GDIINALCFSPNRYWLCAATGPSIKIWDLEGKIIV-DELKQEVISTSSKAEPPQCTSLA 290
            GD+++ L +SP   WL + +        ++  I+V + LK        +        + 
Sbjct: 609 AGDVLD-LAWSPQDLWLASCS--------VDNTIVVWNALKFSEQVAVIRGHAGMVKGVT 457

Query: 291 WSADGQTLFAGYTDNLVRVWQVT 313
           W   G+ L +   D  +RVW+ +
Sbjct: 456 WDPVGRYLASQSDDKTLRVWRTS 388

 Score = 27.7 bits (60), Expect = 7.0,   Method: Compositional matrix adjust.
 Identities = 10/25 (40%), Positives = 17/25 (68%)
 Frame = -1

Query: 291 WSADGQTLFAGYTDNLVRVWQVTIG 315
           WS +G+ L +G  D L+ +WQ++ G
Sbjct: 762 WSENGKFLASGGDDKLIMIWQISRG 688
>17266
          Length = 480

 Score = 47.4 bits (111), Expect = 8e-06,   Method: Compositional matrix adjust.
 Identities = 31/141 (21%), Positives = 65/141 (46%), Gaps = 1/141 (0%)
 Frame = -1

Query: 71  ISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIK 130
           ++ D +  +SG+ D + +LWD+  G   + F GH  D+ ++ +  +     +GS D T +
Sbjct: 435 LAPDMRTFVSGACDASAKLWDVRDGMCKQTFSGHESDINAITYFPNGHAFATGSDDATCR 256

Query: 131 LWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKL-VKVWNLANCKLKTNHI 189
           L++        +   SH   +  +     S +  ++  G+D     +W++   +      
Sbjct: 255 LFDIRA--DQEIGMYSHDNIICGITSVAFSKSGRLLLGGYDDFNCNIWDVLKQERTGVLA 82

Query: 190 GHTGYLNTVTVSPDGSLCASG 210
           GH   ++ + V+ DGS  A+G
Sbjct: 81  GHDNRVSCLGVTEDGSAVATG 19

 Score = 44.3 bits (103), Expect = 6e-05,   Method: Compositional matrix adjust.
 Identities = 35/119 (29%), Positives = 55/119 (46%), Gaps = 4/119 (3%)
 Frame = -1

Query: 198 VTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDI-INALCFSPNRYWLCAATG--- 253
           ++++PD     SG  D  A LWD+ +G    T  G +  INA+ + PN +    ATG   
Sbjct: 441 LSLAPDMRTFVSGACDASAKLWDVRDGMCKQTFSGHESDINAITYFPNGHAF--ATGSDD 268

Query: 254 PSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFAGYTDNLVRVWQV 312
            + +++D+          QE+   S        TS+A+S  G+ L  GY D    +W V
Sbjct: 267 ATCRLFDIRA-------DQEIGMYSHDNIICGITSVAFSKSGRLLLGGYDDFNCNIWDV 112

 Score = 36.6 bits (83), Expect = 0.015,   Method: Compositional matrix adjust.
 Identities = 30/113 (26%), Positives = 48/113 (42%), Gaps = 4/113 (3%)
 Frame = -1

Query: 165 IVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEG 224
            VS   D   K+W++ +   K    GH   +N +T  P+G   A+G  D    L+D+   
Sbjct: 414 FVSGACDASAKLWDVRDGMCKQTFSGHESDINAITYFPNGHAFATGSDDATCRLFDIRAD 235

Query: 225 KHLYTLDGGDI---INALCFSPN-RYWLCAATGPSIKIWDLEGKIIVDELKQE 273
           + +      +I   I ++ FS + R  L      +  IWD+        LKQE
Sbjct: 234 QEIGMYSHDNIICGITSVAFSKSGRLLLGGYDDFNCNIWDV--------LKQE 100

 Score = 32.0 bits (71), Expect = 0.29,   Method: Compositional matrix adjust.
 Identities = 39/138 (28%), Positives = 56/138 (40%), Gaps = 11/138 (7%)
 Frame = -1

Query: 108 VLSVAFSSDNRQIVSGSRDKTIKLWNTL-GVCKYTVQDESHSEWVSCVRFSPNSSNPIIV 166
           VLS+A   D R  VSG+ D + KLW+   G+CK T     H   ++ + + PN       
Sbjct: 444 VLSLA--PDMRTFVSGACDASAKLWDVRDGMCKQTFS--GHESDINAITYFPNGH---AF 286

Query: 167 SCGWDKLVKVWNLANCKL----KTNHIGHTGYLN------TVTVSPDGSLCASGGKDGQA 216
           + G D        A C+L        IG   + N      +V  S  G L   G  D   
Sbjct: 285 ATGSDD-------ATCRLFDIRADQEIGMYSHDNIICGITSVAFSKSGRLLLGGYDDFNC 127

Query: 217 MLWDLNEGKHLYTLDGGD 234
            +WD+ + +    L G D
Sbjct: 126 NIWDVLKQERTGVLAGHD 73

 Score = 31.2 bits (69), Expect = 0.53,   Method: Compositional matrix adjust.
 Identities = 26/123 (21%), Positives = 45/123 (36%), Gaps = 3/123 (2%)
 Frame = -1

Query: 10  TLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFV--- 66
           T  GH   +  I   P       + S D T  ++ +  D+      +  +  H + +   
Sbjct: 348 TFSGHESDINAITYFPN-GHAFATGSDDATCRLFDIRADQ------EIGMYSHDNIICGI 190

Query: 67  SDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRD 126
           + V  S  G+  L G  D    +WD+     T    GH   V  +  + D   + +GS D
Sbjct: 189 TSVAFSKSGRLLLGGYDDFNCNIWDVLKQERTGVLAGHDNRVSCLGVTEDGSAVATGSWD 10

Query: 127 KTI 129
             +
Sbjct: 9   SFL 1
>01768
          Length = 1424

 Score = 47.0 bits (110), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 36/129 (27%), Positives = 61/129 (47%), Gaps = 13/129 (10%)
 Frame = +3

Query: 146 SHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHI----GHTGYLNTVTVS 201
           +H++ V  V++SPN  N +  SC  D+ +++WN      K N +     H+  +N +  +
Sbjct: 831 AHTDSVEDVQWSPNEGN-VFASCSVDRTLRIWNTQQKPSKANVLTVPEAHSRDINVINWN 1007

Query: 202 P-DGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDI------INALCFSPNRYWLCAATGP 254
           P +  L ASGG DG   +WDL   ++               + +L ++P    + AA+G 
Sbjct: 1008PIEKHLLASGGDDGIIKIWDLRMFRNKPVSAQASFKLHSQPVTSLEWNPQDSSVLAASGE 1187

Query: 255 --SIKIWDL 261
              I IWD 
Sbjct: 1188DDQITIWDF 1214

 Score = 44.3 bits (103), Expect = 6e-05,   Method: Compositional matrix adjust.
 Identities = 36/142 (25%), Positives = 70/142 (49%), Gaps = 12/142 (8%)
 Frame = +3

Query: 93  TTGTTTRR--FVGHTKDVLSVAFSSDNRQI-VSGSRDKTIKLWNTL---GVCKYTVQDES 146
           ++G TT +  +  HT  V  V +S +   +  S S D+T+++WNT             E+
Sbjct: 795 SSGWTTEKSSYAAHTDSVEDVQWSPNEGNVFASCSVDRTLRIWNTQQKPSKANVLTVPEA 974

Query: 147 HSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSP---- 202
           HS  ++ + ++P   + ++ S G D ++K+W+L   + K      +  L++  V+     
Sbjct: 975 HSRDINVINWNPIEKH-LLASGGDDGIIKIWDLRMFRNKPVSAQASFKLHSQPVTSLEWN 1151

Query: 203 --DGSLCASGGKDGQAMLWDLN 222
             D S+ A+ G+D Q  +WD +
Sbjct: 1152PQDSSVLAASGEDDQITIWDFS 1217
>01249
          Length = 1743

 Score = 46.6 bits (109), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 64/299 (21%), Positives = 116/299 (38%), Gaps = 14/299 (4%)
 Frame = -1

Query: 31   ILSASRDKTII-MWKLTR-DETNYGI--PQRALRGHSHFVSDVVISSDGQFALSGSWDGT 86
            +L A+++K +I +W L++ DE+ + I  P +        VS +V+S DG F L+ S    
Sbjct: 1575 LLGAAQNKPVIHVWPLSKKDESQHKIVCPGK--------VSVLVVSPDGLFCLA-SISEK 1423

Query: 87   LRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQD-- 144
            + +W++T G+     +    +   + F+ D  Q V  +    + +W+   V   T Q   
Sbjct: 1422 IYIWEMTGGSLVG-LLSDFNEATKIQFTDDGSQFVVATSSGHLNIWDFARVVTTTSQRAR 1246

Query: 145  --------ESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLN 196
                     +HSE ++ +          + S   D   K+W++ +  L    +  TG   
Sbjct: 1245 GLKPGRTINAHSEPITGLHVGCGGPAARVASSSSDGTCKLWDMLSGALLRTMVYETGV-- 1072

Query: 197  TVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDIINALCFSPNRYWLCAATGPSI 256
                                ++ D  E   L  LD GDI            LC+     I
Sbjct: 1071 ------------------GCLIMDKQEHFLLAGLDNGDI------------LCSPLFGQI 982

Query: 257  KIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFAGYTDNLVRVWQVTIG 315
                 + ++ V +   +      +      T LA+S+DGQ L +G  +  V +W +  G
Sbjct: 981  S----QSEVFVSKHTTKAGERVLQGHSDAVTCLAFSSDGQRLASGSQNGKVIIWNMESG 817

 Score = 38.9 bits (89), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 18/43 (41%), Positives = 29/43 (67%)
 Frame = -1

Query: 56  QRALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTT 98
           +R L+GHS  V+ +  SSDGQ   SGS +G + +W++ +G +T
Sbjct: 936 ERVLQGHSDAVTCLAFSSDGQRLASGSQNGKVIIWNMESGDST 808
>26107
          Length = 1338

 Score = 45.4 bits (106), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 67/265 (25%), Positives = 97/265 (36%), Gaps = 23/265 (8%)
 Frame = -3

Query: 71   ISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVA-FSSDNRQIVSGSRDKTI 129
            IS+D Q  L+ S D T+ LWD+ T T    F+GH   V SVA   S   Q  SG+RD  I
Sbjct: 1060 ISNDSQ-CLTASGDQTVALWDVETTTKVTTFIGHKCSVRSVASCPSSPAQCASGARDGHI 884

Query: 130  KLWNTLGVCKYTVQDESHSEWV---SCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKT 186
             LW++    K   Q  S    V   S  +  P     I  + G   ++       C    
Sbjct: 883  MLWDSRVNKKREHQPCSQVHQVCPQSGHQSKPAKHRRIHRAAGPKGVMDTQQSVTC---- 716

Query: 187  NHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWD------------------LNEGKHLY 228
                       V    D  + +SG  DG   +WD                   +   H+ 
Sbjct: 715  -----------VLYQTDNLIISSGANDGCVKMWDTRKWYTNTTTSLPVPVHTFDYPGHMR 569

Query: 229  TLDGGDIINALCFSPNRYWLCAA-TGPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCT 287
             L G   I  +C  P +  L  + T   +  + L G+       QE +    + +     
Sbjct: 568  RLKG---IVTMCMDPWKSQLFVSYTDNKVYRYQLAGQY---REPQEYVYAGHRND-TFFV 410

Query: 288  SLAWSADGQTLFAGYTDNLVRVWQV 312
              A S DG+ L +G   N   +W+V
Sbjct: 409  RCAISPDGKYLLSGSGRNTGVIWEV 335

 Score = 39.3 bits (90), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 28/87 (32%), Positives = 48/87 (55%), Gaps = 5/87 (5%)
 Frame = -3

Query: 51  NYGIPQRALR-GHSH--FVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRF-VGHTK 106
            Y  PQ  +  GH +  F     IS DG++ LSGS   T  +W++        F +GHT+
Sbjct: 469 QYREPQEYVYAGHRNDTFFVRCAISPDGKYLLSGSGRNTGVIWEVDKPNKRPLFLIGHTE 290

Query: 107 DVLSVAF-SSDNRQIVSGSRDKTIKLW 132
           DV +V + S+D  ++ + S D+++++W
Sbjct: 289 DVSAVDWCSTDVCKLATVSDDRSLRIW 209

 Score = 34.7 bits (78), Expect = 0.047,   Method: Compositional matrix adjust.
 Identities = 51/239 (21%), Positives = 86/239 (35%), Gaps = 18/239 (7%)
 Frame = -3

Query: 3   EQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGH 62
           E  T   T  GH   V  +A+ P  P    S +RD  I++W             R  +  
Sbjct: 997 ETTTKVTTFIGHKCSVRSVASCPSSPAQCASGARDGHIMLWD-----------SRVNKKR 851

Query: 63  SHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVS 122
            H     V     Q   SG      +   +      +  +   + V  V + +DN  I S
Sbjct: 850 EHQPCSQVHQVCPQ---SGHQSKPAKHRRIHRAAGPKGVMDTQQSVTCVLYQTDNLIISS 680

Query: 123 GSRDKTIKLWNT----------LGVCKYTVQDESHSEWVSCVR---FSPNSSNPIIVSCG 169
           G+ D  +K+W+T          L V  +T     H   +  +      P  S  + VS  
Sbjct: 679 GANDGCVKMWDTRKWYTNTTTSLPVPVHTFDYPGHMRRLKGIVTMCMDPWKSQ-LFVSYT 503

Query: 170 WDKLVKVWNLANCKLKTNHIGHTGYLN-----TVTVSPDGSLCASGGKDGQAMLWDLNE 223
            +K+ + + LA    +     + G+ N        +SPDG    SG      ++W++++
Sbjct: 502 DNKVYR-YQLAGQYREPQEYVYAGHRNDTFFVRCAISPDGKYLLSGSGRNTGVIWEVDK 329
>19140
          Length = 573

 Score = 45.1 bits (105), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 25/71 (35%), Positives = 37/71 (52%)
 Frame = -3

Query: 59  LRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNR 118
           L+GH+  V  +V++ DG   LSGS DGT+RLW L        F  H + V ++  +    
Sbjct: 499 LKGHTDNVKALVLNRDGTQCLSGSSDGTIRLWSLGQQRCVATFRVHDEGVWALQANESFT 320

Query: 119 QIVSGSRDKTI 129
            + SG RD  +
Sbjct: 319 TLYSGGRDHQV 287

 Score = 32.3 bits (72), Expect = 0.27,   Method: Compositional matrix adjust.
 Identities = 14/41 (34%), Positives = 22/41 (53%)
 Frame = -3

Query: 190 GHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTL 230
           GHT  +  + ++ DG+ C SG  DG   LW L + + + T 
Sbjct: 493 GHTDNVKALVLNRDGTQCLSGSSDGTIRLWSLGQQRCVATF 371
>33180
          Length = 460

 Score = 44.7 bits (104), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 25/73 (34%), Positives = 40/73 (54%), Gaps = 1/73 (1%)
 Frame = -2

Query: 62  HSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIV 121
           HS  +  ++ SSD    + G+ DG L ++D  +   T +   H  DV +VAF+ D+ QI+
Sbjct: 456 HSFCIFSLMFSSDNTEIVGGANDGCLYVYDRESNQRTLKIDAHDDDVNAVAFADDSSQIL 277

Query: 122 -SGSRDKTIKLWN 133
            SG  D   K+W+
Sbjct: 276 YSGGDDGLCKVWD 238
>01462
          Length = 995

 Score = 44.3 bits (103), Expect = 7e-05,   Method: Compositional matrix adjust.
 Identities = 23/79 (29%), Positives = 42/79 (53%)
 Frame = +2

Query: 31  ILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVISSDGQFALSGSWDGTLRLW 90
           + + + D+ I +W +       G    A+ GH  ++  VV+ +D Q  +S S DGT+R+W
Sbjct: 242 LYAGAGDRKIHVWDI-----EAGQYLNAMEGHKDYIHKVVMKNDAQECVSASEDGTVRMW 406

Query: 91  DLTTGTTTRRFVGHTKDVL 109
           D+ + T T   +  +K+ L
Sbjct: 407 DIRSSTETVHCLEPSKNEL 463

 Score = 42.7 bits (99), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 24/104 (23%), Positives = 40/104 (38%), Gaps = 12/104 (11%)
 Frame = +2

Query: 171 DKLVKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKH-LYT 229
           D+ + VW++   +      GH  Y++ V +  D   C S  +DG   +WD+      ++ 
Sbjct: 260 DRKIHVWDIEAGQYLNAMEGHKDYIHKVVMKNDAQECVSASEDGTVRMWDIRSSTETVHC 439

Query: 230 LDG-----------GDIINALCFSPNRYWLCAATGPSIKIWDLE 262
           L+            G  +  L   P   WL    GP +  W L 
Sbjct: 440 LEPSKNELCSRPLLGKWLRCLALDPEEGWLVCGGGPKLSAWHLR 571

 Score = 39.7 bits (91), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 40/189 (21%), Positives = 68/189 (35%), Gaps = 3/189 (1%)
 Frame = +2

Query: 80  SGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCK 139
           +G+ D  + +WD+  G       GH   +  V   +D ++ VS S D T+++W+      
Sbjct: 248 AGAGDRKIHVWDIEAGQYLNAMEGHKDYIHKVVMKNDAQECVSASEDGTVRMWDI----- 412

Query: 140 YTVQDESHSEWVSCVRFSPNS--SNPIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNT 197
                 S +E V C+  S N   S P++                            +L  
Sbjct: 413 -----RSSTETVHCLEPSKNELCSRPLL--------------------------GKWLRC 499

Query: 198 VTVSP-DGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDIINALCFSPNRYWLCAATGPSI 256
           + + P +G L   GG    A  W L         D   +   +    + + L A T P +
Sbjct: 500 LALDPEEGWLVCGGGPKLSA--WHLRTLAPTTIFDTPSVSQNVALFHDEFILSAGTSPVM 673

Query: 257 KIWDLEGKI 265
             W L+G +
Sbjct: 674 NHWRLDGTL 700
>19863
          Length = 502

 Score = 44.3 bits (103), Expect = 7e-05,   Method: Compositional matrix adjust.
 Identities = 23/60 (38%), Positives = 33/60 (55%)
 Frame = +1

Query: 74  DGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWN 133
           DG   +SGS D ++ +WD+  G    R  GH   V  V FS D   ++S S D T+++WN
Sbjct: 4   DGLQLVSGSSDMSIVVWDVENGVQKLRLQGHAGWVNDVHFSQDQCWLLSCSNDNTVRIWN 183

 Score = 40.8 bits (94), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 22/76 (28%), Positives = 41/76 (53%)
 Frame = +1

Query: 31  ILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVISSDGQFALSGSWDGTLRLW 90
           ++S S D +I++W     +   G+ +  L+GH+ +V+DV  S D  + LS S D T+R+W
Sbjct: 16  LVSGSSDMSIVVW-----DVENGVQKLRLQGHAGWVNDVHFSQDQCWLLSCSNDNTVRIW 180

Query: 91  DLTTGTTTRRFVGHTK 106
           ++         + H +
Sbjct: 181 NIEESDQIPIVMEHKR 228

 Score = 30.8 bits (68), Expect = 0.67,   Method: Compositional matrix adjust.
 Identities = 18/63 (28%), Positives = 28/63 (44%)
 Frame = +1

Query: 165 IVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEG 224
           +VS   D  + VW++ N   K    GH G++N V  S D     S   D    +W++ E 
Sbjct: 16  LVSGSSDMSIVVWDVENGVQKLRLQGHAGWVNDVHFSQDQCWLLSCSNDNTVRIWNIEES 195

Query: 225 KHL 227
             +
Sbjct: 196 DQI 204
>26939
          Length = 388

 Score = 43.9 bits (102), Expect = 8e-05,   Method: Compositional matrix adjust.
 Identities = 19/59 (32%), Positives = 32/59 (54%)
 Frame = +2

Query: 75  GQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWN 133
           G++ +S S D T+R+WDL      +    H     S+ F   +  ++SGS D+T+K+W 
Sbjct: 2   GKYLVSASDDKTIRVWDLRNKRCMKTLYAHQHFCTSIDFHKAHPYVISGSVDQTVKVWE 178

 Score = 37.4 bits (85), Expect = 0.009,   Method: Compositional matrix adjust.
 Identities = 19/61 (31%), Positives = 31/61 (50%)
 Frame = +2

Query: 31 ILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVISSDGQFALSGSWDGTLRLW 90
          ++SAS DKTI +W L           + L  H HF + +       + +SGS D T+++W
Sbjct: 11 LVSASDDKTIRVWDLRNKRC-----MKTLYAHQHFCTSIDFHKAHPYVISGSVDQTVKVW 175

Query: 91 D 91
          +
Sbjct: 176E 178

 Score = 32.7 bits (73), Expect = 0.22,   Method: Compositional matrix adjust.
 Identities = 19/62 (30%), Positives = 31/62 (50%), Gaps = 1/62 (1%)
 Frame = +2

Query: 118 RQIVSGSRDKTIKLWNTLGV-CKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKV 176
           + +VS S DKTI++W+     C  T+    H     C     + ++P ++S   D+ VKV
Sbjct: 5   KYLVSASDDKTIRVWDLRNKRCMKTLYAHQH----FCTSIDFHKAHPYVISGSVDQTVKV 172

Query: 177 WN 178
           W 
Sbjct: 173 WE 178

 Score = 30.4 bits (67), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 17/67 (25%), Positives = 30/67 (44%)
 Frame = +2

Query: 245 RYWLCAATGPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFAGYTD 304
           +Y + A+   +I++WDL  K  +  L          A    CTS+ +      + +G  D
Sbjct: 5   KYLVSASDDKTIRVWDLRNKRCMKTLY---------AHQHFCTSIDFHKAHPYVISGSVD 157

Query: 305 NLVRVWQ 311
             V+VW+
Sbjct: 158 QTVKVWE 178
>30295
          Length = 593

 Score = 43.1 bits (100), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 33/128 (25%), Positives = 56/128 (43%), Gaps = 4/128 (3%)
 Frame = +2

Query: 97  TTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRF 156
           T R    H   + ++ +++D+R +VS S+D  + +W+     K        S WV    +
Sbjct: 221 TRRTLRXHLAKIYAMHWATDSRNLVSASQDGKLIVWDGYTTNKVHAI-PLRSSWVMTCAY 397

Query: 157 SPNSSNPIIVSCGWDKLVKVWNL----ANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGK 212
           +P  S   +   G D +  +++L     N ++     GHTGYL+      D  +  S G 
Sbjct: 398 AP--SGGYVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFIDDNQIVTSSG- 568

Query: 213 DGQAMLWD 220
           D    LWD
Sbjct: 569 DMTCALWD 592

 Score = 40.8 bits (94), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 37/134 (27%), Positives = 56/134 (41%), Gaps = 4/134 (2%)
 Frame = +2

Query: 4   QMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHS 63
           QM  R TL+ H   +  +       +++ SAS+D  +I+W        + IP R     S
Sbjct: 212 QMRTRRTLRXHLAKIYAMHWATDSRNLV-SASQDGKLIVWDGYTTNKVHAIPLR-----S 373

Query: 64  HFVSDVVISSDGQFALSGSWDGTLRLWDLTTGT----TTRRFVGHTKDVLSVAFSSDNRQ 119
            +V     +  G +   G  D    ++ L T       +R   GHT  +    F  DN Q
Sbjct: 374 SWVMTCAYAPSGGYVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFIDDN-Q 550

Query: 120 IVSGSRDKTIKLWN 133
           IV+ S D T  LW+
Sbjct: 551 IVTSSGDMTCALWD 592
>04088
          Length = 511

 Score = 43.1 bits (100), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 23/70 (32%), Positives = 35/70 (50%), Gaps = 2/70 (2%)
 Frame = +3

Query: 66  VSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSV--AFSSDNRQIVSG 123
           V+ V  + DGQ +L  S D T+RL D  TG     F GH      +    ++++  +VSG
Sbjct: 39  VTSVTFTRDGQCSLVSSQDNTVRLMDKDTGEMLNEFTGHKHSQYKIDSCLNNEDTLVVSG 218

Query: 124 SRDKTIKLWN 133
           S D  +  W+
Sbjct: 219 SEDGKVYFWD 248

 Score = 35.0 bits (79), Expect = 0.044,   Method: Compositional matrix adjust.
 Identities = 20/71 (28%), Positives = 33/71 (46%), Gaps = 2/71 (2%)
 Frame = +3

Query: 191 HTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDI--INALCFSPNRYWL 248
           H+ Y     ++ + +L  SG +DG+   WDL E K + TLD      +++L F      L
Sbjct: 159 HSQYKIDSCLNNEDTLVVSGSEDGKVYFWDLVEAKLVDTLDHKTTRPVHSLSFHHAELCL 338

Query: 249 CAATGPSIKIW 259
             A    + +W
Sbjct: 339 MTACADKVFLW 371

 Score = 30.8 bits (68), Expect = 0.77,   Method: Compositional matrix adjust.
 Identities = 26/105 (24%), Positives = 48/105 (45%), Gaps = 2/105 (1%)
 Frame = +3

Query: 32  LSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWD 91
           L +S+D T+   +L   +T   + +     HS +  D  ++++    +SGS DG +  WD
Sbjct: 78  LVSSQDNTV---RLMDKDTGEMLNEFTGHKHSQYKIDSCLNNEDTLVVSGSEDGKVYFWD 248

Query: 92  LTTGTTTRRFVGH--TKDVLSVAFSSDNRQIVSGSRDKTIKLWNT 134
           L         + H  T+ V S++F      +++   DK   LW +
Sbjct: 249 LVEAKLVDT-LDHKTTRPVHSLSFHHAELCLMTACADKVF-LWRS 377
>15780
          Length = 735

 Score = 42.7 bits (99), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 18/50 (36%), Positives = 28/50 (56%)
 Frame = -1

Query: 84  DGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWN 133
           D T+ +WD+ +GT       HT  V ++ FS D   + SG  D +I+LW+
Sbjct: 711 DHTVIVWDIASGTAVAHLTAHTDTVYALCFSRDGTVLASGGMDNSIRLWD 562

 Score = 38.5 bits (88), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 20/55 (36%), Positives = 29/55 (52%)
 Frame = -1

Query: 167 SCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDL 221
           + G D  V VW++A+     +   HT  +  +  S DG++ ASGG D    LWDL
Sbjct: 723 TAGADHTVIVWDIASGTAVAHLTAHTDTVYALCFSRDGTVLASGGMDNSIRLWDL 559
>01598
          Length = 1545

 Score = 42.4 bits (98), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 48/174 (27%), Positives = 83/174 (47%), Gaps = 16/174 (9%)
 Frame = +1

Query: 30  MILSASRDKTIIMWKLTRDETNY--GIP-QRALRGH--SHFVSDVVI---SSDGQFALSG 81
           +I + S+D+TI +W L++ +  +   +P QR   G   S F   + I    S+ +  +S 
Sbjct: 106 LIATGSKDRTIRVWTLSQGKQIFMKKLPNQRREAGDTGSRFKVWLAIHWLKSNPEQLVSS 285

Query: 82  SWDGTLRLWDL--TTGTTTRRFV-----GHTKDVLSVAFSS-DNRQIVSGSRDKTIKLWN 133
           S  G L LW L  T G   + F       H + V ++  S  D++ + + ++D+ + LW+
Sbjct: 286 SSGGDLLLWSLRYTKGQAYQTFQTSDYRPHMRPVFNICASGPDSKTLCTFAQDRQVVLWD 465

Query: 134 TLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTN 187
            L   +      +    V CVR SP     + V  G D +++ WN++N   KTN
Sbjct: 466 -LETMEAVASMATLGGHVYCVRTSPIDPGRVAVGVG-DSMIRTWNMSN---KTN 612

 Score = 40.0 bits (92), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 25/79 (31%), Positives = 39/79 (49%), Gaps = 2/79 (2%)
 Frame = +1

Query: 57   RALRGHSHFVSDVVISSDGQFAL-SGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSS 115
            R L GHS  V+D+  S      L S  +D    +WD+  GT   +F GH   +L+  FS 
Sbjct: 1282 RELSGHSQRVTDMSWSPHHDARLVSVGYDAEAFVWDVQKGTALAQFKGHMGRLLTCQFSG 1461

Query: 116  -DNRQIVSGSRDKTIKLWN 133
             D   +++G  D ++ +W 
Sbjct: 1462 LDPDLVMTGGSDASVHVWR 1518

 Score = 34.3 bits (77), Expect = 0.069,   Method: Compositional matrix adjust.
 Identities = 23/78 (29%), Positives = 38/78 (48%), Gaps = 1/78 (1%)
 Frame = +1

Query: 147  HSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSP-DGS 205
            HS+ V+ + +SP+  +  +VS G+D    VW++          GH G L T   S  D  
Sbjct: 1297 HSQRVTDMSWSPHH-DARLVSVGYDAEAFVWDVQKGTALAQFKGHMGRLLTCQFSGLDPD 1473

Query: 206  LCASGGKDGQAMLWDLNE 223
            L  +GG D    +W +++
Sbjct: 1474 LVMTGGSDASVHVWRVSQ 1527

 Score = 28.1 bits (61), Expect = 5.5,   Method: Compositional matrix adjust.
 Identities = 16/56 (28%), Positives = 25/56 (44%)
 Frame = +1

Query: 204 GSLCASGGKDGQAMLWDLNEGKHLYTLDGGDIINALCFSPNRYWLCAATGPSIKIW 259
           G L A+G KD    +W L++GK ++          +   PN+      TG   K+W
Sbjct: 100 GCLIATGSKDRTIRVWTLSQGKQIF----------MKKLPNQRREAGDTGSRFKVW 237

 Score = 27.7 bits (60), Expect = 6.8,   Method: Compositional matrix adjust.
 Identities = 38/171 (22%), Positives = 65/171 (38%), Gaps = 26/171 (15%)
 Frame = +1

Query: 120 IVSGSRDKTIKLWNTLGVCKYTVQDESHSE-------------WVSCVRFSPNSSNPIIV 166
           I +GS+D+TI++W TL   K     +  ++             W++      N    +  
Sbjct: 109 IATGSKDRTIRVW-TLSQGKQIFMKKLPNQRREAGDTGSRFKVWLAIHWLKSNPEQLVSS 285

Query: 167 SCGWDKLVKVWNLANCKLKTNHIGHTG--------YLNTVTVSPDGSLCASGGKDGQAML 218
           S G D L  +W+L   K +      T           N     PD     +  +D Q +L
Sbjct: 286 SSGGDLL--LWSLRYTKGQAYQTFQTSDYRPHMRPVFNICASGPDSKTLCTFAQDRQVVL 459

Query: 219 WDLNEGKHLYTLD--GGDI--INALCFSPNRYWLCAATGPS-IKIWDLEGK 264
           WDL   + + ++   GG +  +      P R  +    G S I+ W++  K
Sbjct: 460 WDLETMEAVASMATLGGHVYCVRTSPIDPGR--VAVGVGDSMIRTWNMSNK 606
>15118
          Length = 1074

 Score = 41.6 bits (96), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 47/222 (21%), Positives = 90/222 (40%), Gaps = 5/222 (2%)
 Frame = +3

Query: 43  WKLTRDETNYGIPQRALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRF- 101
           +KL     ++G   R     +     V ISS G +   G   G L +++L +G     F 
Sbjct: 12  YKLDCKRFHHGAQHRFTTAQA-----VDISSCGNYVAVGYSSGHLDIYNLQSGKHRGSFG 176

Query: 102 --VGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWN--TLGVCKYTVQDESHSEWVSCVRFS 157
             V H   V  VAF + N  +++   D  IK W   +    +  +++   SE +S +   
Sbjct: 177 DTVAHVSGVRGVAFDAFNCLLITAGGDCDIKFWRFGSRDRARVLLKELKMSEGISRILLH 356

Query: 158 PNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAM 217
            +S+   +V    D  V V ++   ++     GH+  +  ++ S DG    +   D    
Sbjct: 357 RDSNMLAVVL--EDFTVSVIDVDTLRVVRVFSGHSNSITDLSFSGDGRWLITASMDCTVR 530

Query: 218 LWDLNEGKHLYTLDGGDIINALCFSPNRYWLCAATGPSIKIW 259
            W L  G+ +        + +L  SP++ +L  +    + ++
Sbjct: 531 TWSLVHGRLIDCFAVEAAVTSLTMSPSQDFLATSHVGDVGVY 656
>16105
          Length = 960

 Score = 41.2 bits (95), Expect = 6e-04,   Method: Compositional matrix adjust.
 Identities = 40/166 (24%), Positives = 70/166 (42%), Gaps = 9/166 (5%)
 Frame = -2

Query: 147 HSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTN-------HIGHTGYLNTVT 199
           H   V  +++ P++ N +I S   D  VKVW + +  L TN        +GH      + 
Sbjct: 578 HKGAVLDIQWCPHNDN-VIASASDDCTVKVWQIPDSGLVTNLTDPVVDLVGHQKRCCLIV 402

Query: 200 VSPDG-SLCASGGKDGQAMLWDLNEGKHLYTLDGGDIINALCFSPNRYWL-CAATGPSIK 257
             P   ++  S G D + + W++  G+ +  +D  D+I  + F+ N   L C      ++
Sbjct: 401 WHPSAQNVLVSAGADNKILFWNVGTGEPMLEVDVPDMIYCMSFNFNGSRLVCTCKDKKLR 222

Query: 258 IWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFAGYT 303
           I D     ++ E K         A+P Q   L    DG+    G++
Sbjct: 221 IIDSHSGAVLKEGK-----CHDGAKPAQACYL---KDGKVFTTGFS 108

 Score = 38.9 bits (89), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 32/127 (25%), Positives = 56/127 (44%), Gaps = 3/127 (2%)
 Frame = -2

Query: 11  LKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRD--ETNYGIPQRALRGHSHFVSD 68
           + GH G V  I   P   ++I SAS D T+ +W++      TN   P   L GH      
Sbjct: 587 VAGHKGAVLDIQWCPHNDNVIASASDDCTVKVWQIPDSGLVTNLTDPVVDLVGHQKRCCL 408

Query: 69  VVISSDGQFAL-SGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDK 127
           +V     Q  L S   D  +  W++ TG      V     +  ++F+ +  ++V   +DK
Sbjct: 407 IVWHPSAQNVLVSAGADNKILFWNVGTGEPMLE-VDVPDMIYCMSFNFNGSRLVCTCKDK 231

Query: 128 TIKLWNT 134
            +++ ++
Sbjct: 230 KLRIIDS 210
>14555
          Length = 627

 Score = 40.4 bits (93), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 26/85 (30%), Positives = 40/85 (47%)
 Frame = -3

Query: 29  DMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVISSDGQFALSGSWDGTLR 88
           D  L  + D T+ +W   +     G+    L GH + VS + IS DG    +GSWD TLR
Sbjct: 427 DCCLGVTNDYTVNVWDALK-----GMRSTILYGHDNRVSCLRISPDGTSLCTGSWDYTLR 263

Query: 89  LWDLTTGTTTRRFVGHTKDVLSVAF 113
           +W         R  GH+ +++ +  
Sbjct: 262 IW------A*ERERGHSSNIIRITL 206

 Score = 31.6 bits (70), Expect = 0.40,   Method: Compositional matrix adjust.
 Identities = 15/49 (30%), Positives = 24/49 (48%)
 Frame = -3

Query: 84  DGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLW 132
           D T+ +WD   G  +    GH   V  +  S D   + +GS D T+++W
Sbjct: 403 DYTVNVWDALKGMRSTILYGHDNRVSCLRISPDGTSLCTGSWDYTLRIW 257

 Score = 28.5 bits (62), Expect = 3.5,   Method: Compositional matrix adjust.
 Identities = 18/56 (32%), Positives = 24/56 (42%), Gaps = 3/56 (5%)
 Frame = -2

Query: 190 GHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDII---NALCFS 242
           GH   +N V   P G   A+G  D    L+DL   + +       II   NA+ FS
Sbjct: 605 GHEADINCVRFYPSGDAFATGSDDATCRLFDLRADREVNCYRKESIIFGCNAVDFS 438
>21921
          Length = 1341

 Score = 40.4 bits (93), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 17/55 (30%), Positives = 30/55 (54%)
 Frame = -1

Query: 190 GHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDIINALCFSPN 244
           GHTG + ++   P G    SG  DG    W+++ G+ + TL  G  + ++ ++PN
Sbjct: 489 GHTGIVRSICPDPTGQWLVSGSDDGTIRFWEVSSGRCMKTLQVGGCVTSVAWNPN 325

 Score = 35.8 bits (81), Expect = 0.025,   Method: Compositional matrix adjust.
 Identities = 14/36 (38%), Positives = 24/36 (66%)
 Frame = -1

Query: 60  RGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTG 95
           +GH+  V  +     GQ+ +SGS DGT+R W++++G
Sbjct: 492 KGHTGIVRSICPDPTGQWLVSGSDDGTIRFWEVSSG 385

 Score = 30.8 bits (68), Expect = 0.69,   Method: Compositional matrix adjust.
 Identities = 22/56 (39%), Positives = 29/56 (51%), Gaps = 3/56 (5%)
 Frame = -1

Query: 91  DLTTGTTTRRFV--GHTKDVLSVAFSSDNRQIVSGSRDKTIKLWN-TLGVCKYTVQ 143
           DL    TT+  V  GHT  V S+      + +VSGS D TI+ W  + G C  T+Q
Sbjct: 531 DLRPFPTTQALVYKGHTGIVRSICPDPTGQWLVSGSDDGTIRFWEVSSGRCMKTLQ 364
>31384
          Length = 474

 Score = 40.4 bits (93), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 21/59 (35%), Positives = 32/59 (54%), Gaps = 2/59 (3%)
 Frame = -1

Query: 77  FALSGSWDGTLRLWDLTTG--TTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWN 133
           F +SGSWD  +  W++     T  +    HT  VL V +S D  ++ + S DKT K+W+
Sbjct: 225 FLISGSWDNKVSCWEVQQSGQTIPKAQQTHTGPVLDVDWSDDGTKVFTASCDKTAKVWD 49

 Score = 37.7 bits (86), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 24/80 (30%), Positives = 38/80 (47%), Gaps = 3/80 (3%)
 Frame = -1

Query: 151 VSCVRFSPNS-SNPIIVSCGWDKLVKVWNLANC--KLKTNHIGHTGYLNTVTVSPDGSLC 207
           VSC++FSP +  +  ++S  WD  V  W +      +      HTG +  V  S DG+  
Sbjct: 267 VSCLKFSPGALPSTFLISGSWDNKVSCWEVQQSGQTIPKAQQTHTGPVLDVDWSDDGTKV 88

Query: 208 ASGGKDGQAMLWDLNEGKHL 227
            +   D  A +WDLN  + +
Sbjct: 87  FTASCDKTAKVWDLNSNQCM 28
>10264
          Length = 416

 Score = 39.3 bits (90), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 25/80 (31%), Positives = 39/80 (48%), Gaps = 2/80 (2%)
 Frame = -1

Query: 57  RALRGHSHFVSDVVISSDGQFAL-SGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSS 115
           R L GHS  V+D+  S      L S  +D    +WD+  GT   +F GH   +L+  FS 
Sbjct: 263 RELSGHSQRVTDMSWSPHHDARLVSVGYDAEAFVWDVQKGTALAQFKGHMGRLLTCQFSG 84

Query: 116 -DNRQIVSGSRDKTIKLWNT 134
            D   +++G  D ++ +W  
Sbjct: 83  LDPDLVMTGGSDASVHVWRV 24

 Score = 34.7 bits (78), Expect = 0.051,   Method: Compositional matrix adjust.
 Identities = 23/78 (29%), Positives = 38/78 (48%), Gaps = 1/78 (1%)
 Frame = -1

Query: 147 HSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSP-DGS 205
           HS+ V+ + +SP+  +  +VS G+D    VW++          GH G L T   S  D  
Sbjct: 248 HSQRVTDMSWSPHH-DARLVSVGYDAEAFVWDVQKGTALAQFKGHMGRLLTCQFSGLDPD 72

Query: 206 LCASGGKDGQAMLWDLNE 223
           L  +GG D    +W +++
Sbjct: 71  LVMTGGSDASVHVWRVSQ 18
>31054
          Length = 392

 Score = 38.5 bits (88), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 22/82 (26%), Positives = 41/82 (50%), Gaps = 8/82 (9%)
 Frame = -2

Query: 59  LRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKD--------VLS 110
           L GH+  ++ + ++SDG   +SG+ +GT+ LWD  TG   +R     +           +
Sbjct: 301 LSGHNAIINTLAVNSDGVL-VSGADNGTMHLWDWRTGYNFQRIHAAVQPGSLDSESGFFA 125

Query: 111 VAFSSDNRQIVSGSRDKTIKLW 132
             F     ++++   DKTIK++
Sbjct: 124 CTFDQSESRLITAEADKTIKVY 59

 Score = 35.4 bits (80), Expect = 0.035,   Method: Compositional matrix adjust.
 Identities = 21/67 (31%), Positives = 29/67 (43%)
 Frame = -2

Query: 161 SNPIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWD 220
           S  +  + G    VK W   +     N  GH   +NT+ V+ DG L  SG  +G   LWD
Sbjct: 382 SKAVHFAXGSPDXVKQWKFPDGNFIQNLSGHNAIINTLAVNSDGVLV-SGADNGTMHLWD 206

Query: 221 LNEGKHL 227
              G + 
Sbjct: 205 WRTGYNF 185
>25880
          Length = 423

 Score = 38.5 bits (88), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 33/99 (33%), Positives = 45/99 (45%), Gaps = 1/99 (1%)
 Frame = +2

Query: 128 TIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTN 187
           T K+WN   V    +    H   V  V F  +S N  IV+   +KLV+V+NL     +  
Sbjct: 2   TGKVWNA--VSGAEIHSFQHKHIVKSVAFDNSSEN--IVTGSNEKLVRVFNLEQPDAEPE 169

Query: 188 -HIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGK 225
            + GHTG +         +L ASG +DG   LW    GK
Sbjct: 170 LYGGHTGAIKR-------ALYASGSEDGTLRLWQTTVGK 265

 Score = 30.0 bits (66), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 19/74 (25%), Positives = 34/74 (45%), Gaps = 1/74 (1%)
 Frame = +2

Query: 62  HSHFVSDVVISSDGQFALSGSWDGTLRLWDLTT-GTTTRRFVGHTKDVLSVAFSSDNRQI 120
           H H V  V   +  +  ++GS +  +R+++L         + GHT  +    ++S     
Sbjct: 53  HKHIVKSVAFDNSSENIVTGSNEKLVRVFNLEQPDAEPELYGGHTGAIKRALYAS----- 217

Query: 121 VSGSRDKTIKLWNT 134
             GS D T++LW T
Sbjct: 218 --GSEDGTLRLWQT 253

 Score = 28.5 bits (62), Expect = 4.1,   Method: Compositional matrix adjust.
 Identities = 13/18 (72%), Positives = 13/18 (72%)
 Frame = +2

Query: 80  SGSWDGTLRLWDLTTGTT 97
           SGS DGTLRLW  T G T
Sbjct: 215 SGSEDGTLRLWQTTVGKT 268
>14500
          Length = 1238

 Score = 38.1 bits (87), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 24/70 (34%), Positives = 33/70 (47%)
 Frame = +3

Query: 70  VISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTI 129
           +ISS G FA        L +W     +      GHT  VL +A S D   +VS + D+T+
Sbjct: 378 LISSHG-FA-----QNQLIIWKYPAMSRVAELTGHTARVLHMAMSPDGETVVSAAADETL 539

Query: 130 KLWNTLGVCK 139
           +LW    V K
Sbjct: 540 RLWKCFTVDK 569

 Score = 35.8 bits (81), Expect = 0.021,   Method: Compositional matrix adjust.
 Identities = 30/112 (26%), Positives = 48/112 (42%), Gaps = 5/112 (4%)
 Frame = +3

Query: 205 SLCASGG--KDGQAMLWDLNEGKHLYTLDGGDIINALCFSPNRYWLCAATGPS---IKIW 259
           SL ASGG   D     W+ N G +L ++D    + AL +S     L ++ G +   + IW
Sbjct: 243 SLLASGGGTADRHIHFWNCNTGTNLSSVDTKSQVCALLWSKEHRELISSHGFAQNQLIIW 422

Query: 260 DLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFAGYTDNLVRVWQ 311
                  V EL              +   +A S DG+T+ +   D  +R+W+
Sbjct: 423 KYPAMSRVAELT---------GHTARVLHMAMSPDGETVVSAAADETLRLWK 551

 Score = 27.3 bits (59), Expect(2) = 0.034,   Method: Compositional matrix adjust.
 Identities = 25/100 (25%), Positives = 38/100 (38%), Gaps = 3/100 (3%)
 Frame = +3

Query: 123 GSRDKTIKLWN-TLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGW--DKLVKVWNL 179
           G+ D+ I  WN   G    +V  +S      C          +I S G+  ++L+ +W  
Sbjct: 264 GTADRHIHFWNCNTGTNLSSVDTKSQV----CALLWSKEHRELISSHGFAQNQLI-IWKY 428

Query: 180 ANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLW 219
                     GHT  +  + +SPDG    S   D    LW
Sbjct: 429 PAMSRVAELTGHTARVLHMAMSPDGETVVSAAADETLRLW 548

 Score = 26.6 bits (57), Expect(2) = 0.034,   Method: Compositional matrix adjust.
 Identities = 23/68 (33%), Positives = 33/68 (48%), Gaps = 5/68 (7%)
 Frame = +2

Query: 59  LRGHSHFVSDVVISSDGQFALSGSWDGTLRLW--DLTTGTTTR---RFVGHTKDVLSVAF 113
           L GHS  V  +  S DG++  SG+ D  L +W   +T G +T+    F  H   V ++A 
Sbjct: 47  LSGHSQEVCGLRWSPDGKYLASGANDNLLCVWPAQVTGGNSTQPLHTFSQHQAAVKALAV 226

Query: 114 SSDNRQIV 121
            S   Q V
Sbjct: 227 VSLAAQSV 250

 Score = 30.4 bits (67), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 15/36 (41%), Positives = 21/36 (58%)
 Frame = +3

Query: 59  LRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTT 94
           L GH+  V  + +S DG+  +S + D TLRLW   T
Sbjct: 453 LTGHTARVLHMAMSPDGETVVSAAADETLRLWKCFT 560

 Score = 28.5 bits (62), Expect = 3.5,   Method: Compositional matrix adjust.
 Identities = 16/29 (55%), Positives = 19/29 (65%), Gaps = 2/29 (6%)
 Frame = +2

Query: 289 LAWSADGQTLFAGYTDNLVRVW--QVTIG 315
           L WS DG+ L +G  DNL+ VW  QVT G
Sbjct: 77  LRWSPDGKYLASGANDNLLCVWPAQVTGG 163
>10162
          Length = 1629

 Score = 38.1 bits (87), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 50/238 (21%), Positives = 87/238 (36%), Gaps = 35/238 (14%)
 Frame = +3

Query: 30  MILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVISSDGQFALSGSWDGTLRL 89
           ++L+ ++   + +W++   + +     + L+ H        I  +G++   G  DG ++L
Sbjct: 69  VLLAGTQGGEVWLWQVPSQDYS---KMKMLQSHGQPSLCGKILPNGKYVCVGYSDGVVKL 239

Query: 90  WDLTTGTTTRRF----------------------------VGHTKDVLSVAFSSDNRQIV 121
           WDL TGT    +                               T  +L V  S+DN  I+
Sbjct: 240 WDLKTGTAVHTWQHSVMPEEEMPERNSSDEEDGEEVEVEREEDTVAILCVDCSADNALIM 419

Query: 122 SGSRDKTIKLWN-------TLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLV 174
           SG  D T K++N       +   C  +   +     V  V F P S  P   +      V
Sbjct: 420 SGCADATAKVFNVSSGKLXSAFNCAASQDSQDKDNSVESVAFCPVS--PYAATATNSGSV 593

Query: 175 KVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDG 232
           +VW+L    +  +   H   +  +  S   +L  +   DG   +WD   G     L G
Sbjct: 594 QVWDLPT-SVARHSFQHPEGVCKLQWSSSTALLYTACLDGVMRVWDARSGASKAVLTG 764

 Score = 37.4 bits (85), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 27/116 (23%), Positives = 47/116 (40%), Gaps = 2/116 (1%)
 Frame = +3

Query: 18  VTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVISSDGQF 77
           V  +A  P  P    +A+   ++ +W L      +         H   V  +  SS    
Sbjct: 528 VESVAFCPVSP-YAATATNSGSVQVWDLPTSVARHSFQ------HPEGVCKLQWSSSTAL 686

Query: 78  ALSGSWDGTLRLWDLTTGTTTRRFVGHTKD--VLSVAFSSDNRQIVSGSRDKTIKL 131
             +   DG +R+WD  +G +     GH ++  +L    + D   +VSGS D T ++
Sbjct: 687 LYTACLDGVMRVWDARSGASKAVLTGHARNSCILDFDVTRDGTCLVSGSEDGTARV 854

 Score = 36.2 bits (82), Expect = 0.018,   Method: Compositional matrix adjust.
 Identities = 29/129 (22%), Positives = 49/129 (37%), Gaps = 10/129 (7%)
 Frame = +3

Query: 198 VTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTL---------DGGDIINALCFSP-NRYW 247
           V  S D +L  SG  D  A +++++ GK              D  + + ++ F P + Y 
Sbjct: 387 VDCSADNALIMSGCADATAKVFNVSSGKLXSAFNCAASQDSQDKDNSVESVAFCPVSPYA 566

Query: 248 LCAATGPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFAGYTDNLV 307
             A    S+++WDL   +     +           P     L WS+    L+    D ++
Sbjct: 567 ATATNSGSVQVWDLPTSVARHSFQH----------PEGVCKLQWSSSTALLYTACLDGVM 716

Query: 308 RVWQVTIGT 316
           RVW    G 
Sbjct: 717 RVWDARSGA 743
>04524
          Length = 1340

 Score = 35.8 bits (81), Expect = 0.021,   Method: Compositional matrix adjust.
 Identities = 23/91 (25%), Positives = 41/91 (45%), Gaps = 1/91 (1%)
 Frame = -1

Query: 47   RDETNYGIPQRALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRF-VGHT 105
            +DE       + L GH   V DV ++      ++   D  +R+           + +GHT
Sbjct: 1076 KDEGEVKTHGQLLLGHLSMVLDVCLTGREGHVVTCDRDEKIRVSQFPNAYNIHTYCLGHT 897

Query: 106  KDVLSVAFSSDNRQIVSGSRDKTIKLWNTLG 136
            + V  + +  + R ++SGS D T++ WN  G
Sbjct: 896  QFVNCLVYVEEFRVLISGSGDCTVRAWNMEG 804

 Score = 35.0 bits (79), Expect = 0.038,   Method: Compositional matrix adjust.
 Identities = 33/130 (25%), Positives = 56/130 (43%), Gaps = 12/130 (9%)
 Frame = -1

Query: 110  SVAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDES-----------HSEWVSCVRFSP 158
            SV F+SD  Q++    DKT  ++      +  V+DE            H   V  V  + 
Sbjct: 1169 SVTFTSDEGQVIVA--DKTGDVYTFPTTTQVEVKDEGEVKTHGQLLLGHLSMVLDVCLTG 996

Query: 159  NSSNPIIVSCGWDKLVKVWNLANC-KLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAM 217
               +  +V+C  D+ ++V    N   + T  +GHT ++N +    +  +  SG  D    
Sbjct: 995  REGH--VVTCDRDEKIRVSQFPNAYNIHTYCLGHTQFVNCLVYVEEFRVLISGSGDCTVR 822

Query: 218  LWDLNEGKHL 227
             W++ EGK L
Sbjct: 821  AWNM-EGKQL 795
>31864
          Length = 545

 Score = 35.8 bits (81), Expect = 0.021,   Method: Compositional matrix adjust.
 Identities = 32/129 (24%), Positives = 51/129 (39%), Gaps = 8/129 (6%)
 Frame = +2

Query: 189 IGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDIINALCFSPNRYWL 248
           + HTG +N + +S DG++  +  KD  A L+D      L T      +N+   SP    +
Sbjct: 41  VDHTGGINDMQLSKDGTMFVTASKDTTAKLFDSESLMCLKTYKTERPVNSAAISPILDHV 220

Query: 249 CAATGP--------SIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFA 300
               G         S K    + +      ++E         P    SLA+  DG++  +
Sbjct: 221 VLGGGQDAMEVTTTSTKAGKFDSRFFHLIYEEEFARLKGHFGP--INSLAFHPDGKSYAS 394

Query: 301 GYTDNLVRV 309
           G  D  VRV
Sbjct: 395 GGEDGFVRV 421
>29912
          Length = 510

 Score = 35.8 bits (81), Expect = 0.022,   Method: Compositional matrix adjust.
 Identities = 30/117 (25%), Positives = 52/117 (44%)
 Frame = +3

Query: 61  GHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQI 120
           G   ++  V    +G +   G+  G +++WD+T     R   GH   V S++++S    +
Sbjct: 3   GPEEYIGAVSWIKEGNYLALGTSTGEVQVWDVTQQKKLRTMAGHAARVGSLSWNS--FIV 176

Query: 121 VSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVW 177
            SGSR   I   +      +      HS+ V  +R+SP+     + S   D L+ VW
Sbjct: 177 SSGSRSGNIHHHDVRVADHHVGTLSGHSQEVCGLRWSPDGK--YLASGANDNLLCVW 341

 Score = 35.0 bits (79), Expect = 0.038,   Method: Compositional matrix adjust.
 Identities = 35/126 (27%), Positives = 55/126 (43%), Gaps = 4/126 (3%)
 Frame = +3

Query: 194 YLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDIINALCFSPNRYWLCAATG 253
           Y+  V+   +G+  A G   G+  +WD+ + K L T+  G        S N + + + + 
Sbjct: 15  YIGAVSWIKEGNYLALGTSTGEVQVWDVTQQKKLRTM-AGHAARVGSLSWNSFIVSSGS- 188

Query: 254 PSIKIWDLEGKIIVDELK--QEVISTSSKAEPPQCTSLAWSADGQTLFAGYTDNLVRVW- 310
                    G I   +++     + T S      C  L WS DG+ L +G  DNL+ VW 
Sbjct: 189 -------RSGNIHHHDVRVADHHVGTLSGHSQEVC-GLRWSPDGKYLASGANDNLLCVWP 344

Query: 311 -QVTIG 315
            QVT G
Sbjct: 345 AQVTGG 362

 Score = 28.9 bits (63), Expect = 2.9,   Method: Compositional matrix adjust.
 Identities = 32/118 (27%), Positives = 54/118 (45%), Gaps = 5/118 (4%)
 Frame = +3

Query: 1   MTEQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALR 60
           +T+Q  LR T+ GH     ++ +      ++ S SR   I    +   + + G     L 
Sbjct: 96  VTQQKKLR-TMAGH---AARVGSLSWNSFIVSSGSRSGNIHHHDVRVADHHVGT----LS 251

Query: 61  GHSHFVSDVVISSDGQFALSGSWDGTLRLW--DLTTGTTTR---RFVGHTKDVLSVAF 113
           GHS  V  +  S DG++  SG+ D  L +W   +T G +T+    F  H   V ++A+
Sbjct: 252 GHSQEVCGLRWSPDGKYLASGANDNLLCVWPAQVTGGNSTQPLHTFSQHQAAVKALAW 425
>11915
          Length = 737

 Score = 35.8 bits (81), Expect = 0.024,   Method: Compositional matrix adjust.
 Identities = 25/84 (29%), Positives = 40/84 (47%), Gaps = 1/84 (1%)
 Frame = +1

Query: 50  TNYGIPQRALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVL 109
           TN    QR  R   +  S +V+++       G   G ++LW+  TG      + H   V 
Sbjct: 388 TNNCYKQRWKRQQQNDSSTLVLAT-------GHVSGRIKLWNCETGKLLIEMMDHKATVH 546

Query: 110 SVAFSSDNRQ-IVSGSRDKTIKLW 132
            + F++DN   ++S S D T+KLW
Sbjct: 547 DLHFAADNSLCLMSASHDGTVKLW 618

 Score = 32.0 bits (71), Expect = 0.31,   Method: Compositional matrix adjust.
 Identities = 19/71 (26%), Positives = 34/71 (47%), Gaps = 2/71 (2%)
 Frame = +1

Query: 155 RFSPNSSNPIIVSCGW-DKLVKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLC-ASGGK 212
           R   N S+ ++++ G     +K+WN    KL    + H   ++ +  + D SLC  S   
Sbjct: 418 RQQQNDSSTLVLATGHVSGRIKLWNCETGKLLIEMMDHKATVHDLHFAADNSLCLMSASH 597

Query: 213 DGQAMLWDLNE 223
           DG   LW+ ++
Sbjct: 598 DGTVKLWEFDD 630
>27270
          Length = 1078

 Score = 35.4 bits (80), Expect = 0.027,   Method: Compositional matrix adjust.
 Identities = 29/101 (28%), Positives = 49/101 (48%), Gaps = 1/101 (0%)
 Frame = +2

Query: 12  KGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQ-RALRGHSHFVSDVV 70
           KGH+  VT +         + S+S D  +I W +    T + I + +A  G  H V  V 
Sbjct: 263 KGHSKAVTDMCWRAD-GRTLYSSSLDGHVIGWNV---NTLHMIEKWKATSGRHHGVHCVC 430

Query: 71  ISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSV 111
           + S  +   +   D T+++WDLTT    + F GH+ +V+ +
Sbjct: 431 LCSSSRLLTA---DHTIKMWDLTTKNVLQEFSGHSTEVIKL 544

 Score = 35.0 bits (79), Expect = 0.037,   Method: Compositional matrix adjust.
 Identities = 33/124 (26%), Positives = 56/124 (45%), Gaps = 3/124 (2%)
 Frame = +2

Query: 72  SSDGQFALSGSWDGTLRLWDLTTGTTTRRF-VGHTKDVLSVAFSSDNRQIVSGSRDKTIK 130
           ++D      GS DG++ L+ + T T T     GH+K V  + + +D R + S S D  + 
Sbjct: 170 AADSAVVAVGSADGSVGLYSVETHTYTHMLNKGHSKAVTDMCWRADGRTLYSSSLDGHVI 349

Query: 131 LW--NTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNH 188
            W  NTL + +           V CV     SS+ ++ +   D  +K+W+L    +    
Sbjct: 350 GWNVNTLHMIEKWKATSGRHHGVHCVCLC--SSSRLLTA---DHTIKMWDLTTKNVLQEF 514

Query: 189 IGHT 192
            GH+
Sbjct: 515 SGHS 526
>13890
          Length = 630

 Score = 35.4 bits (80), Expect = 0.028,   Method: Compositional matrix adjust.
 Identities = 37/170 (21%), Positives = 64/170 (37%), Gaps = 13/170 (7%)
 Frame = +1

Query: 87  LRLWDLTTGTTTRRFVGHTKD---VLSVAFSSDNRQIVS-------GSRDKTIKLWNTLG 136
           +++WD+       R + H +    V  V FS D +++ S        S D++I  W+   
Sbjct: 52  IQVWDVRHPEVPVRVLTHKEQLGQVQDVMFSHDGQEVFSCGDVVSRESSDRSIMAWDFRT 231

Query: 137 VCKYTVQDESHSEWVSCVRFSPNSSNPII-VSCGWDKLVKVWNLANCKLKTNHIGH--TG 193
               + Q       V+ +   P  S  +     G+  +                GH   G
Sbjct: 232 GVILSNQIFQERYTVTRLMLHPYQSQFLAQTQAGYIAVFSTQRPYKMNKNKRFEGHKTAG 411

Query: 194 YLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDIINALCFSP 243
           Y    ++S DGS+  SG  DG+   +  N  K + TL  G ++  +   P
Sbjct: 412 YNIGASLSQDGSIVYSGSSDGKLHCYSFNTTKKIRTLHCGQVVMDVTSHP 561
>34005
          Length = 456

 Score = 35.4 bits (80), Expect = 0.033,   Method: Compositional matrix adjust.
 Identities = 33/121 (27%), Positives = 49/121 (40%), Gaps = 7/121 (5%)
 Frame = +1

Query: 34  ASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLT 93
           A+   T   W+ TR       PQ         V  +  S D  F  SGS D ++ +WD T
Sbjct: 49  ATSTTTTYAWRATRWGFCPLTPQE--------VCGLSWSPDATFLASGSNDNSVNIWDST 204

Query: 94  TGTTT---RRFVGHTKDVLSVAFSSDNRQIVS---GSRDKTIKLWNT-LGVCKYTVQDES 146
            G           H   V +VA+     ++++   G+ D+ I+ WNT  G C   V  +S
Sbjct: 205 LGMDVPPLHTLTSHQAAVKAVAWCPWQTRMLATGGGTNDRHIRFWNTNTGACVKAVDTQS 384

Query: 147 H 147
            
Sbjct: 385 Q 387

 Score = 29.6 bits (65), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 13/33 (39%), Positives = 18/33 (54%)
 Frame = +1

Query: 283 PPQCTSLAWSADGQTLFAGYTDNLVRVWQVTIG 315
           P +   L+WS D   L +G  DN V +W  T+G
Sbjct: 112 PQEVCGLSWSPDATFLASGSNDNSVNIWDSTLG 210
>31474
          Length = 403

 Score = 35.0 bits (79), Expect = 0.045,   Method: Compositional matrix adjust.
 Identities = 27/95 (28%), Positives = 46/95 (48%), Gaps = 6/95 (6%)
 Frame = -3

Query: 146 SHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLAN----CKLKTNHIGHTGYLNTVTVS 201
           +H E   CV ++P  +  ++ SCG DK++K+W        CK  T    HT  + ++  S
Sbjct: 311 AHDEHAWCVAWNPTGT--LLASCGSDKIIKIWGKEGDNWVCK-STLTDAHTRTVRSLGWS 141

Query: 202 PDGSLCASGGKDGQAMLWDLNEGKH--LYTLDGGD 234
           P G+  +S   D    +W    G+   + TL+G +
Sbjct: 140 PCGNYLSSASFDATTAVWSRKGGEFECIATLEGHE 36
>05642
          Length = 445

 Score = 34.7 bits (78), Expect = 0.055,   Method: Compositional matrix adjust.
 Identities = 20/71 (28%), Positives = 33/71 (46%), Gaps = 2/71 (2%)
 Frame = -1

Query: 191 HTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDI--INALCFSPNRYWL 248
           H+ Y     ++ + +L  SG +DG+   WDL E K + TLD      +++L F      L
Sbjct: 412 HSQYKIDSCLNNEDTLVVSGSEDGKVYFWDLVEAKLVDTLDHKTTRPVHSLSFHHAELCL 233

Query: 249 CAATGPSIKIW 259
             A    + +W
Sbjct: 232 MTACADKVFLW 200

 Score = 28.5 bits (62), Expect = 4.1,   Method: Compositional matrix adjust.
 Identities = 20/75 (26%), Positives = 35/75 (46%), Gaps = 2/75 (2%)
 Frame = -1

Query: 62  HSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGH--TKDVLSVAFSSDNRQ 119
           HS +  D  ++++    +SGS DG +  WDL         + H  T+ V S++F      
Sbjct: 412 HSQYKIDSCLNNEDTLVVSGSEDGKVYFWDLVEAKLVDT-LDHKTTRPVHSLSFHHAELC 236

Query: 120 IVSGSRDKTIKLWNT 134
           +++   DK   LW +
Sbjct: 235 LMTACADKVF-LWRS 194
>15972
          Length = 1069

 Score = 34.3 bits (77), Expect = 0.066,   Method: Compositional matrix adjust.
 Identities = 18/55 (32%), Positives = 27/55 (49%)
 Frame = +3

Query: 53  GIPQRALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKD 107
           G P+R   GH   V  + +   G+  L+ S D TLRLW+   G     F+ + K+
Sbjct: 207 G*PERTFSGHKGPVRHLAVHPSGKLTLTVSQDRTLRLWNNMNGRIA--FISNMKE 365

 Score = 29.6 bits (65), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 15/75 (20%), Positives = 33/75 (44%)
 Frame = +3

Query: 190 GHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDIINALCFSPNRYWLC 249
           GH G +  + V P G L  +  +D    LW+   G+  +  +  +   ++ ++P   +  
Sbjct: 231 GHKGPVRHLAVHPSGKLTLTVSQDRTLRLWNNMNGRIAFISNMKEAAESVRWAPGGLYYV 410

Query: 250 AATGPSIKIWDLEGK 264
            A    + ++ +E K
Sbjct: 411 VAFRSHLDVYSVESK 455

 Score = 28.1 bits (61), Expect(2) = 3.8,   Method: Compositional matrix adjust.
 Identities = 12/37 (32%), Positives = 21/37 (56%)
 Frame = +3

Query: 99  RRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTL 135
           R F GH   V  +A     +  ++ S+D+T++LWN +
Sbjct: 219 RTFSGHKGPVRHLAVHPSGKLTLTVSQDRTLRLWNNM 329

 Score = 18.5 bits (36), Expect(2) = 3.8,   Method: Compositional matrix adjust.
 Identities = 9/16 (56%), Positives = 11/16 (68%)
 Frame = +2

Query: 79  LSGSWDGTLRLWDLTT 94
            S S DGTL LW ++T
Sbjct: 158 FSTSEDGTLCLWRVST 205
>35607
          Length = 475

 Score = 33.9 bits (76), Expect = 0.087,   Method: Compositional matrix adjust.
 Identities = 18/47 (38%), Positives = 23/47 (48%)
 Frame = +2

Query: 202 PDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDIINALCFSPNRYWL 248
           PDG+   +GG D     WDL EG+ L   D    I +L + P   WL
Sbjct: 8   PDGTKLWTGGLDNTVRSWDLREGRQLQQHDFSSQIFSLGYCPTGDWL 148
>15337
          Length = 860

 Score = 33.5 bits (75), Expect = 0.10,   Method: Compositional matrix adjust.
 Identities = 23/75 (30%), Positives = 36/75 (48%)
 Frame = -1

Query: 151 VSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCASG 210
           +S   FSP S    +V  G D  ++V+N  + +L      + G L  V  SPDG    +G
Sbjct: 320 ISEFAFSPCSRYLAVV--GQDGHLRVFNYNSMELIGTMKSYFGGLLCVCWSPDGKYIVTG 147

Query: 211 GKDGQAMLWDLNEGK 225
           G+D    +W  +E +
Sbjct: 146 GEDDLVTVWSFHEKR 102

 Score = 29.3 bits (64), Expect = 2.2,   Method: Compositional matrix adjust.
 Identities = 27/107 (25%), Positives = 50/107 (46%)
 Frame = -1

Query: 93  TTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVS 152
           +T     R+V  T  +   AFS  +R +    +D  ++++N   + +     +S+   + 
Sbjct: 365 STRNPLYRWVVGTGAISEFAFSPCSRYLAVVGQDGHLRVFNYNSM-ELIGTMKSYFGGLL 189

Query: 153 CVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVT 199
           CV +SP+     IV+ G D LV VW+    ++     GH  ++N V 
Sbjct: 188 CVCWSPDGK--YIVTGGEDDLVTVWSFHEKRVVCRGHGHKSWVNVVA 54
>17807
          Length = 484

 Score = 33.5 bits (75), Expect = 0.13,   Method: Compositional matrix adjust.
 Identities = 31/142 (21%), Positives = 61/142 (42%), Gaps = 11/142 (7%)
 Frame = -2

Query: 74  DGQFALSGSWDGTLRLWDLTTGTTT--RRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKL 131
           D ++ LSGS DG +RLW++     T      G +  + + +F  + R  V G+ D     
Sbjct: 426 DDRYFLSGSLDGKIRLWNIPDKKVTMWNELSGSSNLITTASFCHNGRLAVVGTYDGRCIF 247

Query: 132 WNTLGVCKYTVQD-------ESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKL 184
           + T  +  YT+ +        +    ++ +   P     ++ S   D  V++++L +  L
Sbjct: 246 YTTDQLKYYTMLNVRSTRGRNARGRKITGIEAMPGEEKILVTS--NDSRVRLYSLKDLTL 73

Query: 185 KTNHIGHTGYLNTV--TVSPDG 204
              + G T   + +  + SP G
Sbjct: 72  TCKYKGCTNNSSQIKASFSPTG 7
>17298
          Length = 476

 Score = 33.1 bits (74), Expect = 0.15,   Method: Compositional matrix adjust.
 Identities = 16/51 (31%), Positives = 29/51 (56%)
 Frame = -1

Query: 84  DGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNT 134
           DG +   ++ +G   R++  H   V  V F+ ++  I+SGS D T++ W+T
Sbjct: 275 DGVVVGNNVASGQALRKYRDHAGTVNCVKFNEESTVILSGSLDNTVRAWDT 123

 Score = 30.8 bits (68), Expect = 0.80,   Method: Compositional matrix adjust.
 Identities = 24/82 (29%), Positives = 40/82 (48%), Gaps = 2/82 (2%)
 Frame = -1

Query: 53  GIPQRALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTT--RRFVGHTKDVLS 110
           G   R  R H+  V+ V  + +    LSGS D T+R WD  + + T  +     T  V S
Sbjct: 242 GQALRKYRDHAGTVNCVKFNEESTVILSGSLDNTVRAWDTRSRSHTPIQVLDEATDSVTS 63

Query: 111 VAFSSDNRQIVSGSRDKTIKLW 132
           +  S  + +I++GS D  ++ +
Sbjct: 62  IQVS--DYEILTGSADGRVRRY 3
>00825
          Length = 1821

 Score = 33.1 bits (74), Expect = 0.15,   Method: Compositional matrix adjust.
 Identities = 47/239 (19%), Positives = 90/239 (37%), Gaps = 3/239 (1%)
 Frame = -2

Query: 80   SGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCK 139
            SG+ DG L  W+L       R   H   V  +A  S  +   S   DKTIK W +L    
Sbjct: 1820 SGACDGELICWNLPKQQMACRVQAHDGIVHGMAAHSSGQYFFSCGSDKTIKQW-SLDPEG 1644

Query: 140  YTVQDESHSEWVSCVRFSPNS--SNPIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNT 197
                +  ++    C+  S +    + I V+ G    V VW+    +   +       ++ 
Sbjct: 1643 TIAPEPVNTLLAKCIYTSLDHHWKDDIFVTSG--SRVDVWDEKRSEPMRSFSWGVESVHH 1470

Query: 198  VTVSP-DGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDIINALCFSPNRYWLCAATGPSI 256
            V  +P +  L  +   D   +L+D+     L  +      NAL ++P   +   +     
Sbjct: 1469 VKFNPVETYLLGAAAHDRSILLYDMRGSAPLRKVVMKMRTNALSWNPMEAFTITSANEDG 1290

Query: 257  KIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFAGYTDNLVRVWQVTIG 315
             ++  + + +   L      T++  +   C +      G+   +   D ++R++ V  G
Sbjct: 1289 NLYTFDMRKLSMPLNMHRDHTAAVMDVDYCPT------GREFVSAGYDKVIRIFPVDKG 1131
>20662
          Length = 1220

 Score = 32.7 bits (73), Expect = 0.18,   Method: Compositional matrix adjust.
 Identities = 36/126 (28%), Positives = 56/126 (44%), Gaps = 19/126 (15%)
 Frame = +2

Query: 119 QIVSGSRD-------KTIKLWNTLGVCKYTVQDE-----------SHSEWVSCVRFSPNS 160
           Q+ +G RD       K +   +T GV  + +QDE            H +  + V  S NS
Sbjct: 245 QLEAGLRDAAWVDSHKVLVGLDTGGVALWELQDEDKMFSMLSSACEHDDMTASV--SINS 418

Query: 161 SNPIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSP-DGSLCASGGKDGQAMLW 219
                +S  +D  +KVWN     L T +  H+  +  V   P + +L  S  +DG+ +LW
Sbjct: 419 DXSHYLSASYDHGIKVWNTDLTSLYT-YRAHSDIVWDVQCHPTEPALFLSCSQDGKIVLW 595

Query: 220 DLNEGK 225
           D+ E K
Sbjct: 596 DVRESK 613
>16199
          Length = 694

 Score = 32.3 bits (72), Expect = 0.28,   Method: Compositional matrix adjust.
 Identities = 14/41 (34%), Positives = 21/41 (51%)
 Frame = +2

Query: 74  DGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFS 114
           DG    +G+ D  +++WDL        F GH   V S++FS
Sbjct: 104 DGLIFATGTEDSVIKIWDLKERANVANFQGHQGPVTSISFS 226

 Score = 27.7 bits (60), Expect = 6.0,   Method: Compositional matrix adjust.
 Identities = 14/52 (26%), Positives = 28/52 (53%), Gaps = 1/52 (1%)
 Frame = +2

Query: 151 VSCVRFSPNSSNPIIVSCG-WDKLVKVWNLANCKLKTNHIGHTGYLNTVTVS 201
           ++C +F P+    +I + G  D ++K+W+L       N  GH G + +++ S
Sbjct: 80  LTCAQFHPDG---LIFATGTEDSVIKIWDLKERANVANFQGHQGPVTSISFS 226

 Score = 27.3 bits (59), Expect = 8.6,   Method: Compositional matrix adjust.
 Identities = 12/38 (31%), Positives = 18/38 (47%)
 Frame = +2

Query: 195 LNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDG 232
           L      PDG + A+G +D    +WDL E  ++    G
Sbjct: 80  LTCAQFHPDGLIFATGTEDSVIKIWDLKERANVANFQG 193
>12140
          Length = 727

 Score = 32.0 bits (71), Expect = 0.33,   Method: Compositional matrix adjust.
 Identities = 32/108 (29%), Positives = 50/108 (46%), Gaps = 6/108 (5%)
 Frame = +2

Query: 118 RQIVSGSRDKTIKLWNTLGVCKYTVQD-ESHSEWVSCVRFSPNSSNP--IIVSCGWDKLV 174
           ++ VSG  D  +K+W          Q  E HS+WV  V ++P+   P  +I SC  D  V
Sbjct: 263 KRFVSGGCDNLVKIWREDETGWVEDQKLEGHSDWVRDVAWAPSIGLPRNVIASCSQDCRV 442

Query: 175 KVW-NLANCKLKTNHI--GHTGYLNTVTVSPDGSLCASGGKDGQAMLW 219
            +W N  +    T+ I    +  +  V+ S  G++ A  G D +  LW
Sbjct: 443 IIWTNDGSSNQWTSRILNKFSDVVWHVSWSVTGNILAVSGGDNKVTLW 586

 Score = 31.2 bits (69), Expect = 0.56,   Method: Compositional matrix adjust.
 Identities = 28/84 (33%), Positives = 40/84 (47%), Gaps = 4/84 (4%)
 Frame = +2

Query: 11  LKGHNGWVTQIATTPQF---PDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVS 67
           L+GH+ WV  +A  P      ++I S S+D  +I+W  T D ++     R L   S  V 
Sbjct: 344 LEGHSDWVRDVAWAPSIGLPRNVIASCSQDCRVIIW--TNDGSSNQWTSRILNKFSDVVW 517

Query: 68  DVVISSDGQ-FALSGSWDGTLRLW 90
            V  S  G   A+SG  D  + LW
Sbjct: 518 HVSWSVTGNILAVSGG-DNKVTLW 586
>27475
          Length = 369

 Score = 31.6 bits (70), Expect = 0.41,   Method: Compositional matrix adjust.
 Identities = 14/42 (33%), Positives = 21/42 (50%)
 Frame = +2

Query: 2  TEQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMW 43
          TE  T++     H GWVT +  +P    + LS S D  + +W
Sbjct: 29 TEGETVKCAFTSHTGWVTGVDWSPTREHLFLSGSYDNVLKLW 154

 Score = 28.1 bits (61), Expect = 4.7,   Method: Compositional matrix adjust.
 Identities = 30/97 (30%), Positives = 49/97 (50%), Gaps = 3/97 (3%)
 Frame = +2

Query: 93  TTGTTTR-RFVGHTKDVLSVAFSSDNRQI-VSGSRDKTIKLWNTLGVCKYTVQDES-HSE 149
           T G T +  F  HT  V  V +S     + +SGS D  +KLW+T    K T+ D + H +
Sbjct: 29  TEGETVKCAFTSHTGWVTGVDWSPTREHLFLSGSYDNVLKLWDTRSP-KATLYDMNWHED 205

Query: 150 WVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKT 186
            +  V +S      +++S G D  + V++ ++ KL T
Sbjct: 206 RILAVDWSIPE---LLLSGGVDNKLHVFSYSSAKLGT 307
>12841
          Length = 1364

 Score = 31.6 bits (70), Expect = 0.42,   Method: Compositional matrix adjust.
 Identities = 29/124 (23%), Positives = 47/124 (37%), Gaps = 12/124 (9%)
 Frame = +1

Query: 68  DVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIV-SGSRD 126
           D+V    GQF  +    G +  W L       R    T  V S+ FS  N  I+ +G  D
Sbjct: 442 DLVAVGYGQFDFTNQKSGLICCWSLKNPEYPERVYTSTHGVTSLDFSVANANILAAGYYD 621

Query: 127 KTIKLWNTLGVCKYTVQD--ESHS---------EWVSCVRFSPNSSNPIIVSCGWDKLVK 175
             + ++N        + D  E+H          +W+   R S      +++S   D  V 
Sbjct: 622 GGVAIYNVRSTSDEPILDNQETHGKHLGPVWQIQWIEKERGSGEERAEVLISISTDGRVT 801

Query: 176 VWNL 179
            W++
Sbjct: 802 QWSI 813
>15745
          Length = 1183

 Score = 31.2 bits (69), Expect = 0.58,   Method: Compositional matrix adjust.
 Identities = 17/62 (27%), Positives = 31/62 (50%)
 Frame = +2

Query: 121 VSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLA 180
           ++ + + TI+ W+     +    + +H + V  + F+PN     + SCG D  VK W+  
Sbjct: 629 IATANEATIRGWDLRSKQQTYQMEGAHGQLVRDLDFNPNRQY-YLASCGDDCRVKFWDTR 805

Query: 181 NC 182
           NC
Sbjct: 806 NC 811
>27681
          Length = 465

 Score = 30.8 bits (68), Expect = 0.78,   Method: Compositional matrix adjust.
 Identities = 22/71 (30%), Positives = 33/71 (46%), Gaps = 14/71 (19%)
 Frame = +2

Query: 80  SGSWDGTLRLWDLTTGTTTRR--------------FVGHTKDVLSVAFSSDNRQIVSGSR 125
           SGS D T R+W++T+ T                   V   KDV S+ ++S+   + +GS 
Sbjct: 44  SGSGDSTARIWNMTSETPNNANQLVLRHCIQKGGTEVPSNKDVTSLDWNSEGTLLATGSY 223

Query: 126 DKTIKLWNTLG 136
           D   +LW T G
Sbjct: 224 DGYARLWRTDG 256

 Score = 28.5 bits (62), Expect = 3.3,   Method: Compositional matrix adjust.
 Identities = 23/72 (31%), Positives = 34/72 (47%), Gaps = 10/72 (13%)
 Frame = +2

Query: 29  DMILSASRDKTIIMWKLTRDETNYGIPQRALR-----GHSHFVSDVVISS-----DGQFA 78
           D++ S S D T  +W +T  ET     Q  LR     G +   S+  ++S     +G   
Sbjct: 32  DLLASGSGDSTARIWNMT-SETPNNANQLVLRHCIQKGGTEVPSNKDVTSLDWNSEGTLL 208

Query: 79  LSGSWDGTLRLW 90
            +GS+DG  RLW
Sbjct: 209 ATGSYDGYARLW 244
>03734
          Length = 1963

 Score = 30.4 bits (67), Expect = 0.90,   Method: Compositional matrix adjust.
 Identities = 41/186 (22%), Positives = 81/186 (43%), Gaps = 22/186 (11%)
 Frame = -2

Query: 149  EWVSCVRFSPNSSNPIIVSCGWDKL----VKVWNLANC--KLKTNHIGHTGYLNT----- 197
            E +SC   SP+ +  ++V    +KL    V V NL +   K++   +     LN      
Sbjct: 1317 ERISCSTISPDGT--VVVFSDQEKLRMYKVHVTNLTSLTPKVEVKSVSLPPKLNKYPAQR 1144

Query: 198  VTVSPDGSLCASGGKDGQAMLWDL--NEGKHLYTL-------DGGDIINALCFSPN-RYW 247
            + ++PD     S        +WD+  ++G  L+T+       +G      LC S N +  
Sbjct: 1143 LAITPDNRYLVSATSVSSLQIWDISDDKGTLLHTVRPEETEEEGRHSFTNLCVSDNSKMA 964

Query: 248  LCAATGPSIKIWDL-EGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFAGYTDNL 306
              + +G  + ++ + EG+++    K   +S        Q T+++++   +TL   Y+D+ 
Sbjct: 963  ATSNSGGQVHLYSIAEGEVLC---KLPALSQ-------QATAISFTXAARTLLVTYSDHK 814

Query: 307  VRVWQV 312
            V  + V
Sbjct: 813  VMEFDV 796
>34511
          Length = 1037

 Score = 30.0 bits (66), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 13/33 (39%), Positives = 21/33 (63%)
 Frame = +3

Query: 59 LRGHSHFVSDVVISSDGQFALSGSWDGTLRLWD 91
          L GH + VS + ++ +G    +GSWD  LR+W+
Sbjct: 60 LAGHDNRVSCLGVTENGMSVATGSWDSFLRVWN 158

 Score = 28.5 bits (62), Expect = 3.6,   Method: Compositional matrix adjust.
 Identities = 13/45 (28%), Positives = 23/45 (51%)
 Frame = +3

Query: 147 HSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGH 191
           H   VSC+  + N  +  + +  WD  ++VWN  +C ++ N  G 
Sbjct: 69  HDNRVSCLGVTENGMS--VATGSWDSFLRVWN*VSCTMRINGWGR 197
>31118
          Length = 390

 Score = 30.0 bits (66), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 11/33 (33%), Positives = 22/33 (66%)
 Frame = -2

Query: 147 HSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNL 179
           HS  + C+RFSP++    +++C +D  +K+ +L
Sbjct: 383 HSAEIRCIRFSPSAY--YMLTCSYDSTIKLTDL 291
>27806
          Length = 419

 Score = 29.6 bits (65), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 14/58 (24%), Positives = 25/58 (43%)
 Frame = -1

Query: 162 NPIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLW 219
           +PII +   D   +++++        + GH G +N V   P   L  +   D  A +W
Sbjct: 389 HPIIGTASADHTARIYSIETGACVLTYGGHQGSVNAVRFHPGQDLVLTASGDHTAHVW 216
>01805
          Length = 2124

 Score = 29.3 bits (64), Expect = 2.1,   Method: Compositional matrix adjust.
 Identities = 40/176 (22%), Positives = 74/176 (42%), Gaps = 2/176 (1%)
 Frame = -1

Query: 10  TLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDV 69
           ++ GH   V  ++       ++ SAS D T+ +W L+  +      Q     HS  V   
Sbjct: 591 SVTGHTQAVLDLSWNRNARHVLASASADTTVALWDLSEGKMAMNFTQ-----HSREVQCC 427

Query: 70  V-ISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKT 128
                + Q  L+GS+D T+++ D  +  T  +      +V    ++  N   +    DK 
Sbjct: 426 NWHPQEEQTLLTGSFDNTVKVVDCRSAETCHKSWTVEGEVEKAVWNHHNPLQLLACTDKG 247

Query: 129 IKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNP-IIVSCGWDKLVKVWNLANCK 183
           +     +   K      +HS  V+ V  S  S  P ++++   DK +KVW++ + K
Sbjct: 246 MVYCFDIRHEKPVFSVGAHSSCVTGVCLS--SQIPGLMITTSEDKTMKVWDIQDDK 85
>18320
          Length = 450

 Score = 28.9 bits (63), Expect = 2.5,   Method: Compositional matrix adjust.
 Identities = 22/84 (26%), Positives = 37/84 (44%), Gaps = 13/84 (15%)
 Frame = -2

Query: 111 VAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQ-------------DESHSEWVSCVRFS 157
           V    + + + +GSRD+ + L   L + KY                D++HS W+ C+   
Sbjct: 266 VHLMQNGQLLAAGSRDRYLTL---LDLTKYDPARPKSKKDMQLHCIDKAHSGWIWCMA-- 102

Query: 158 PNSSNPIIVSCGWDKLVKVWNLAN 181
             S N  + +  WD  +KVW+L  
Sbjct: 101 --SLNQHLYTGSWDTKIKVWDLGQ 36

 Score = 27.3 bits (59), Expect = 8.0,   Method: Compositional matrix adjust.
 Identities = 16/67 (23%), Positives = 35/67 (52%), Gaps = 4/67 (5%)
 Frame = -2

Query: 30  MILSASRDKTIIMWKLTRDETNYGIPQRALRGH----SHFVSDVVISSDGQFALSGSWDG 85
           ++ + SRD+ + +  LT+ +      ++ ++ H    +H      ++S  Q   +GSWD 
Sbjct: 242 LLAAGSRDRYLTLLDLTKYDPARPKSKKDMQLHCIDKAHSGWIWCMASLNQHLYTGSWDT 63

Query: 86  TLRLWDL 92
            +++WDL
Sbjct: 62  KIKVWDL 42
>07781
          Length = 1269

 Score = 28.9 bits (63), Expect = 2.6,   Method: Compositional matrix adjust.
 Identities = 21/64 (32%), Positives = 33/64 (51%), Gaps = 5/64 (7%)
 Frame = -2

Query: 76  QFALSGSWDGTLRLWDLTTGT----TTRRFVGHTKDVLSVAFSSDNRQIVS-GSRDKTIK 130
           +   SGS D  L++WDL  GT    T  RF   T  V S+        +++ GS D+ ++
Sbjct: 752 ELIYSGSDDCKLKVWDLRVGTTPVLTNSRF---TMGVTSIQSCPQREHLLAVGSYDENLR 582

Query: 131 LWNT 134
           L++T
Sbjct: 581 LFDT 570
>35695
          Length = 1651

 Score = 28.5 bits (62), Expect = 3.6,   Method: Compositional matrix adjust.
 Identities = 28/152 (18%), Positives = 68/152 (44%), Gaps = 3/152 (1%)
 Frame = -1

Query: 87   LRLWDLTTGTTTRRFVGHTKDVLSV-AFSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDE 145
            L +WD+  G   +    H   ++++ + +     ++S S DKTI +WN   + +     +
Sbjct: 1639 LYVWDVKQGNMVKTLDAHFGRIIALTSVTVGCNMVISSSIDKTINVWNFDKILEEVHPLD 1460

Query: 146  SHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIG--HTGYLNTVTVSPD 203
                 +  V  + +SS  + V+   ++   VW+L   +L    +G   +  ++   ++ +
Sbjct: 1459 RMERPIETVHMAASSS--LCVATTRNQ-TSVWDLETGRLVKVLVGSSRSNXVSQAFITRE 1289

Query: 204  GSLCASGGKDGQAMLWDLNEGKHLYTLDGGDI 235
            G+   +  +    ++W +N+   +  +  GDI
Sbjct: 1288 GTHVLT-AESPSLLVWQMNQTSPVTQVSIGDI 1196
>30108
          Length = 1032

 Score = 26.9 bits (58), Expect = 9.9,   Method: Compositional matrix adjust.
 Identities = 38/158 (24%), Positives = 62/158 (39%), Gaps = 12/158 (7%)
 Frame = +1

Query: 151 VSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKT----------NHIGHTGYLNTVTV 200
           V+ + + P S++ + V+C     V +W++    L             H GH    +   +
Sbjct: 235 VAHLAWQPLSASVLAVAC--QSAVLIWHIEPTSLAARPSSSSVQVLQHSGHCPITHLAWL 408

Query: 201 SPDGSLCASGGKDGQAMLWDLN-EGKHLYTLDGGDIINALCFSPNRYWLCAATGPSI-KI 258
                L ++   D   M W +  E        GG  ++ L  SP+   + AAT  ++ ++
Sbjct: 409 PSANILLSASPVDTAVMAWSVGGEACTALRYLGGGGVSLLACSPDGSKVMAATPATLFRV 588

Query: 259 WDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQ 296
           WD            EV S  S     +CTS  WS DGQ
Sbjct: 589 WD------TTSWHCEVWSQLSG----RCTSACWSHDGQ 672
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31981939|ref|NP_033477.2| tubulin, beta 4 [Mus
musculus]
         (444 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

16482                                                                 469   e-132
13181                                                                 459   e-129
04882                                                                 436   e-122
00276                                                                 275   3e-74
28905                                                                 255   8e-69
31457                                                                 244   4e-65
25015                                                                 243   9e-65
39157                                                                 229   3e-64
12457                                                                 208   3e-54
05902                                                                 155   3e-38
06360                                                                 134   8e-32
03702                                                                 120   2e-27
17215                                                                  83   2e-16
29025                                                                  36   0.038
>16482
          Length = 837

 Score =  469 bits (1206), Expect = e-132,   Method: Compositional matrix adjust.
 Identities = 223/246 (90%), Positives = 226/246 (91%)
 Frame = +1

Query: 1   MREIVHLQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEATGGNYV 60
           MREIVH+QAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEATGG YV
Sbjct: 100 MREIVHMQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEATGGKYV 279

Query: 61  PRAVLVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDAVLDVV 120
           PRAVLVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVD+VLDVV
Sbjct: 280 PRAVLVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVV 459

Query: 121 RKEAESCDCLQGFQXXXXXXXXXXXXXXXXXXXKIREEFPDRIMNTFSVVPSPKVSDTVV 180
           RKEAESCDCLQGFQ                   KIREE+PDRIMNTFSVVPSPKVSDTVV
Sbjct: 460 RKEAESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVVPSPKVSDTVV 639

Query: 181 EPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCL 240
           EPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCL
Sbjct: 640 EPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCL 819

Query: 241 RFPGQL 246
           RFPGQL
Sbjct: 820 RFPGQL 837
>13181
          Length = 1092

 Score =  459 bits (1180), Expect = e-129,   Method: Compositional matrix adjust.
 Identities = 215/220 (97%), Positives = 220/220 (100%)
 Frame = -3

Query: 208  YDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFM 267
            YDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFM
Sbjct: 1090 YDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFM 911

Query: 268  PGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAVFRGRMSMKEVD 327
            PGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAA+FRGRMSMKEVD
Sbjct: 910  PGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAMFRGRMSMKEVD 731

Query: 328  EQMLSVQSKNSSYFVEWIPNNVKTAVCDIPPRGLKMAATFIGNSTAIQELFKRISEQFTA 387
            EQML+VQ+KNSSYFVEWIPNNVKTAVCDIPPRGLKM+ATF+GNSTAIQELFKRISEQFTA
Sbjct: 730  EQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFVGNSTAIQELFKRISEQFTA 551

Query: 388  MFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQD 427
            MFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQD
Sbjct: 550  MFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQD 431
>04882
          Length = 1136

 Score =  436 bits (1120), Expect = e-122,   Method: Compositional matrix adjust.
 Identities = 204/209 (97%), Positives = 209/209 (100%)
 Frame = +2

Query: 219 TPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGS 278
           TPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGS
Sbjct: 320 TPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGS 499

Query: 279 QQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAVFRGRMSMKEVDEQMLSVQSKNS 338
           QQYRALTVPELTQQMFD+KNMMAACDPRHGRYLTVAA+FRGRMSMKEVDEQML+VQ+KNS
Sbjct: 500 QQYRALTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNS 679

Query: 339 SYFVEWIPNNVKTAVCDIPPRGLKMAATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWY 398
           SYFVEWIPNNVKTAVCDIPPRGLKM+ATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWY
Sbjct: 680 SYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWY 859

Query: 399 TGEGMDEMEFTEAESNMNDLVSEYQQYQD 427
           TGEGMDEMEFTEAESNMNDLVSEYQQYQD
Sbjct: 860 TGEGMDEMEFTEAESNMNDLVSEYQQYQD 946
>00276
          Length = 1330

 Score =  275 bits (702), Expect = 3e-74,   Method: Compositional matrix adjust.
 Identities = 131/355 (36%), Positives = 205/355 (57%), Gaps = 8/355 (2%)
 Frame = -3

Query: 78   SGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDAVLDVVRKEAESCDCLQGFQXXX 137
            +G + Q+  P+  V G+  A NN+A+GHYT G ELVD VLD +RK A+ C  LQGF    
Sbjct: 1328 TGTYRQL-SPEQLVTGKEDAANNYARGHYTIGKELVDLVLDRIRKLADQCTGLQGFLIFH 1152

Query: 138  XXXXXXXXXXXXXXXXKIREEFPDRIMNTFSVVPSPKVSDTVVEPYNATLSVHQLVENTD 197
                            ++  ++  +    F + P+P+VS  VVEPYN+ L+ H  +E++D
Sbjct: 1151 SFGGGTGSGFTSLXMERLSVDYGKKSKLEFXIYPAPQVSTAVVEPYNSILTTHTTLEHSD 972

Query: 198  ETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNM 257
              + +DNEA+YDIC R L +  PTY +LN L+   +S +T  LRF G LN DL +   N+
Sbjct: 971  CAFMVDNEAIYDICRRNLDIERPTYTNLNRLIXQIVSSITASLRFDGALNVDLTEFQTNL 792

Query: 258  VPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAVF 317
            VP+PR+HF +  +AP+ S     +  L V E+T   F+  N +  CDPRHG+Y+    ++
Sbjct: 791  VPYPRIHFPLATYAPVISAEKAYHEQLXVAEITNACFEPANQLVKCDPRHGKYMACCMLY 612

Query: 318  RGRMSMKEVDEQMLSVQSKNSSYFVEWIPNNVKTAVCDIPPR--------GLKMAATFIG 369
            RG +  K+V+  + ++++K +  FV+W P   K  +   PP          ++ A   + 
Sbjct: 611  RGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLS 432

Query: 370  NSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQ 424
            N+TAI E + R+  +F  M+ ++AF+HWY GEGM+E EF+EA  ++  L  +Y++
Sbjct: 431  NTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEE 267
>28905
          Length = 425

 Score =  255 bits (651), Expect(2) = 8e-69,   Method: Compositional matrix adjust.
 Identities = 121/129 (93%), Positives = 126/129 (97%), Gaps = 1/129 (0%)
 Frame = -1

Query: 253 LAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLT 312
           +AVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLT
Sbjct: 389 VAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLT 210

Query: 313 VAAVFRGRMSMKEVDEQMLSVQSKNSSYFVEWIPNNVKTAVCDIPPRGLKMAATFIGNST 372
           VAA+FRGRMSMKEVDEQML+VQ+KNSSYFVEWIPNNVKTAVCDIPPRGLKM+ TFIGNST
Sbjct: 209 VAAMFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSGTFIGNST 30

Query: 373 AIQ-ELFKR 380
           AIQ  LFKR
Sbjct: 29  AIQGRLFKR 3

 Score = 23.9 bits (50), Expect(2) = 8e-69,   Method: Composition-based stats.
 Identities = 9/9 (100%), Positives = 9/9 (100%)
 Frame = -2

Query: 242 FPGQLNADL 250
           FPGQLNADL
Sbjct: 424 FPGQLNADL 398
>31457
          Length = 1530

 Score =  244 bits (624), Expect = 4e-65,   Method: Compositional matrix adjust.
 Identities = 113/119 (94%), Positives = 119/119 (100%)
 Frame = +3

Query: 309 RYLTVAAVFRGRMSMKEVDEQMLSVQSKNSSYFVEWIPNNVKTAVCDIPPRGLKMAATFI 368
           +YLTVAA+FRGRMSMKEVDEQML+VQ+KNSSYFVEWIPNNVKTAVCDIPPRGLKM++TFI
Sbjct: 234 KYLTVAAMFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSSTFI 413

Query: 369 GNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQD 427
           GNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQD
Sbjct: 414 GNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQD 590
>25015
          Length = 458

 Score =  243 bits (621), Expect = 9e-65,   Method: Compositional matrix adjust.
 Identities = 113/115 (98%), Positives = 114/115 (99%)
 Frame = -3

Query: 20  FWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEATGGNYVPRAVLVDLEPGTMDSVRSG 79
           FWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEATGG YVPRAVLVDLEPGTMDSVRSG
Sbjct: 363 FWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEATGGKYVPRAVLVDLEPGTMDSVRSG 184

Query: 80  PFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDAVLDVVRKEAESCDCLQGFQ 134
           PFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVD+VLDVVRKEAESCDCLQGFQ
Sbjct: 183 PFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEAESCDCLQGFQ 19
>39157
          Length = 488

 Score =  229 bits (584), Expect(2) = 3e-64,   Method: Compositional matrix adjust.
 Identities = 113/127 (88%), Positives = 117/127 (92%), Gaps = 3/127 (2%)
 Frame = -1

Query: 1   MREIVHLQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEATGGNYV 60
           MREIVHLQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEATGG YV
Sbjct: 443 MREIVHLQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEATGGKYV 264

Query: 61  PRAVLVDLEPGTMDSVRSG-PFG-QIFRPDNFVFGQSGAGNNWAKGHYTE-GAELVDAVL 117
           PRAVLVDLEPGTMDSVRSG PFG +IFRPDNFVFGQSGAGNNW +   T+ GAELVD+VL
Sbjct: 263 PRAVLVDLEPGTMDSVRSGSPFGPKIFRPDNFVFGQSGAGNNWGQKDTTQRGAELVDSVL 84

Query: 118 DVVRKEA 124
           DVVRK  
Sbjct: 83  DVVRKRG 63

 Score = 33.9 bits (76), Expect(2) = 3e-64,   Method: Compositional matrix adjust.
 Identities = 13/13 (100%), Positives = 13/13 (100%)
 Frame = -2

Query: 122 KEAESCDCLQGFQ 134
           KEAESCDCLQGFQ
Sbjct: 70  KEAESCDCLQGFQ 32
>12457
          Length = 781

 Score =  208 bits (530), Expect = 3e-54,   Method: Compositional matrix adjust.
 Identities = 98/239 (41%), Positives = 141/239 (58%)
 Frame = -1

Query: 65  LVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDAVLDVVRKEA 124
           LVDLEP  +D VR+G + Q+F P+  V G+  A NN+A+GHYT G E+VD VLD +RK A
Sbjct: 718 LVDLEPTVVDEVRTGTYRQLFHPEQLVTGKEDAANNYARGHYTIGKEIVDLVLDRIRKLA 539

Query: 125 ESCDCLQGFQXXXXXXXXXXXXXXXXXXXKIREEFPDRIMNTFSVVPSPKVSDTVVEPYN 184
           + C  LQGF                    ++  ++  +    F++ P+P+VS  VVEPYN
Sbjct: 538 DQCTGLQGFLIFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFAIYPAPQVSTAVVEPYN 359

Query: 185 ATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPG 244
           + L+ H  +E++D  + +DNEA+YDIC R L +  PTY +LN L+   +S +T  LRF G
Sbjct: 358 SILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLRFDG 179

Query: 245 QLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAAC 303
            LN DL +   N+VP+PR+HF +  +AP+ S     +  LTV E+T   F+  N M  C
Sbjct: 178 ALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLTVAEITNACFEPANQMVKC 2
>05902
          Length = 1127

 Score =  155 bits (393), Expect = 3e-38,   Method: Compositional matrix adjust.
 Identities = 91/282 (32%), Positives = 158/282 (56%), Gaps = 12/282 (4%)
 Frame = +2

Query: 154 KIREEFPDRIMNTFSVVPS-PKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICF 212
           K+ + FP +++ T+SV P+  ++SD VV+PYN+ L++ +L +N D    +DN AL  I  
Sbjct: 74  KLNDRFPKKLIQTYSVFPNVDEISDVVVQPYNSLLTLKRLTQNADCVVVLDNTALNRIAA 253

Query: 213 RTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAP 272
             L + TPT+  +N LVS  MS  TT LR+PG +N DL  L  +++P PRLHF M G+ P
Sbjct: 254 DRLHIDTPTFAQVNQLVSTVMSTSTTTLRYPGYMNNDLIGLIASLIPTPRLHFLMTGYTP 433

Query: 273 LTSRGS-QQYRALTVPELTQQMFDAKNMMAACDPRHGR----YLTVAAVFRGRMSMKEVD 327
           LT+       R  TV ++ +++   KNMM +  P H +    Y+++  + +G +   +V 
Sbjct: 434 LTTDSQVANVRKTTVLDVMRRLLQPKNMMVST-PVHRQANHCYISILNIIQGEVDPTQVH 610

Query: 328 EQMLSVQSKNSSYFVEWIPNNVKTAVCDIPP---RGLKMAATFIGNSTAIQELFKRISEQ 384
           + +  ++ +  + F+ W P +++ A+    P      +++   + N T+I  LF+RI  Q
Sbjct: 611 KSLQRIRERKLAQFIPWGPASIQVALSRKSPYVQTAHRVSGLMLANHTSISHLFERILRQ 790

Query: 385 FTAMFRRKAFLHWYTGEGM--DEM-EFTEAESNMNDLVSEYQ 423
           +  + +R+AF+  +  E +  D + EF  +   +  LV EYQ
Sbjct: 791 YDKLRKREAFMDQFKKEAIFKDNLDEFDNSREALQLLVDEYQ 916
>06360
          Length = 1896

 Score =  134 bits (337), Expect = 8e-32,   Method: Compositional matrix adjust.
 Identities = 68/179 (37%), Positives = 98/179 (54%), Gaps = 2/179 (1%)
 Frame = -1

Query: 1    MREIVHLQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQL--ERINVYYNEATGGN 58
            MRE + +  GQ G Q+G   WE+   EHGI P G    D  +    +  N +++E   G 
Sbjct: 1710 MRECISVHVGQAGVQMGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGK 1531

Query: 59   YVPRAVLVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDAVLD 118
            +VPRAV VDLEP  +D VR+G + Q+F P+  V G+  A NN+A+GHYT G E+VD VLD
Sbjct: 1530 HVPRAVFVDLEPTVVDEVRTGTYRQLFHPEQLVTGKEDAANNYARGHYTIGKEIVDLVLD 1351

Query: 119  VVRKEAESCDCLQGFQXXXXXXXXXXXXXXXXXXXKIREEFPDRIMNTFSVVPSPKVSD 177
             +RK A+ C  LQGF                    ++  ++  +    F++ P+P+VSD
Sbjct: 1350 RIRKLADQCTGLQGFLIFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFAIYPAPQVSD 1174
>03702
          Length = 1932

 Score =  120 bits (300), Expect = 2e-27,   Method: Compositional matrix adjust.
 Identities = 59/140 (42%), Positives = 83/140 (59%), Gaps = 1/140 (0%)
 Frame = +1

Query: 167  FSVVPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLN 226
            F++ P+P+VS  VVEPYN+ L+ H  +E++D  + +DNEA+YDIC R L +  P Y +LN
Sbjct: 1501 FAIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPXYTNLN 1680

Query: 227  HLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPG-FAPLTSRGSQQYRALT 285
             L+   +S +T  LRF G LN DL +   N+VP P  H   PG   P+ S     +  LT
Sbjct: 1681 RLIGQIVSSITASLRFDGALNVDLTEFQTNLVPTP--HPLPPGHLCPVISAEKAYHEQLT 1854

Query: 286  VPELTQQMFDAKNMMAACDP 305
            V E+T   F+  N +  CDP
Sbjct: 1855 VAEVTNACFEPANQLVKCDP 1914
>17215
          Length = 632

 Score = 83.2 bits (204), Expect = 2e-16,   Method: Compositional matrix adjust.
 Identities = 37/117 (31%), Positives = 68/117 (58%), Gaps = 8/117 (6%)
 Frame = +3

Query: 316 VFRGRMSMKEVDEQMLSVQSKNSSYFVEWIPNNVKTAVCDIPPR--------GLKMAATF 367
           ++RG +  K+V+  + ++++K +  FV+W P   K  +   PP          ++ A   
Sbjct: 6   LYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCM 185

Query: 368 IGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQ 424
           + N+TAI E + R+  +F  M+ ++AF+HWY GEGM+E EF+EA  ++  L  +Y++
Sbjct: 186 LSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEE 356
>29025
          Length = 395

 Score = 35.8 bits (81), Expect = 0.038,   Method: Compositional matrix adjust.
 Identities = 16/16 (100%), Positives = 16/16 (100%)
 Frame = -3

Query: 412 ESNMNDLVSEYQQYQD 427
           ESNMNDLVSEYQQYQD
Sbjct: 354 ESNMNDLVSEYQQYQD 307
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|7106439|ref|NP_035785.1| tubulin, beta 5 [Mus
musculus]
         (444 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

16482                                                                 468   e-132
13181                                                                 460   e-130
04882                                                                 436   e-123
00276                                                                 276   9e-75
28905                                                                 256   4e-69
31457                                                                 248   4e-66
25015                                                                 242   2e-64
39157                                                                 227   1e-63
12457                                                                 209   2e-54
05902                                                                 152   3e-37
06360                                                                 137   1e-32
03702                                                                 120   8e-28
17215                                                                  84   1e-16
29025                                                                  36   0.037
>16482
          Length = 837

 Score =  468 bits (1204), Expect = e-132,   Method: Compositional matrix adjust.
 Identities = 223/246 (90%), Positives = 227/246 (92%)
 Frame = +1

Query: 1   MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLDRISVYYNEATGGKYV 60
           MREIVH+QAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQL+RI+VYYNEATGGKYV
Sbjct: 100 MREIVHMQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEATGGKYV 279

Query: 61  PRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVV 120
           PRA+LVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVV
Sbjct: 280 PRAVLVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVV 459

Query: 121 RKEAESCDCLQGFQXXXXXXXXXXXXXXXXXXXKIREEYPDRIMNTFSVVPSPKVSDTVV 180
           RKEAESCDCLQGFQ                   KIREEYPDRIMNTFSVVPSPKVSDTVV
Sbjct: 460 RKEAESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVVPSPKVSDTVV 639

Query: 181 EPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCL 240
           EPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCL
Sbjct: 640 EPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCL 819

Query: 241 RFPGQL 246
           RFPGQL
Sbjct: 820 RFPGQL 837
>13181
          Length = 1092

 Score =  460 bits (1183), Expect = e-130,   Method: Compositional matrix adjust.
 Identities = 215/220 (97%), Positives = 219/220 (99%)
 Frame = -3

Query: 208  YDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFM 267
            YDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFM
Sbjct: 1090 YDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFM 911

Query: 268  PGFAPLTSRGSQQYRALTVPELTQQVFDAKNMMAACDPRHGRYLTVAAVFRGRMSMKEVD 327
            PGFAPLTSRGSQQYRALTVPELTQQ+FDAKNMMAACDPRHGRYLTVAA+FRGRMSMKEVD
Sbjct: 910  PGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAMFRGRMSMKEVD 731

Query: 328  EQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMAVTFIGNSTAIQELFKRISEQFTA 387
            EQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKM+ TF+GNSTAIQELFKRISEQFTA
Sbjct: 730  EQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFVGNSTAIQELFKRISEQFTA 551

Query: 388  MFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQD 427
            MFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQD
Sbjct: 550  MFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQD 431
>04882
          Length = 1136

 Score =  436 bits (1122), Expect = e-123,   Method: Compositional matrix adjust.
 Identities = 204/209 (97%), Positives = 208/209 (99%)
 Frame = +2

Query: 219 TPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGS 278
           TPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGS
Sbjct: 320 TPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGS 499

Query: 279 QQYRALTVPELTQQVFDAKNMMAACDPRHGRYLTVAAVFRGRMSMKEVDEQMLNVQNKNS 338
           QQYRALTVPELTQQ+FD+KNMMAACDPRHGRYLTVAA+FRGRMSMKEVDEQMLNVQNKNS
Sbjct: 500 QQYRALTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNS 679

Query: 339 SYFVEWIPNNVKTAVCDIPPRGLKMAVTFIGNSTAIQELFKRISEQFTAMFRRKAFLHWY 398
           SYFVEWIPNNVKTAVCDIPPRGLKM+ TFIGNSTAIQELFKRISEQFTAMFRRKAFLHWY
Sbjct: 680 SYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWY 859

Query: 399 TGEGMDEMEFTEAESNMNDLVSEYQQYQD 427
           TGEGMDEMEFTEAESNMNDLVSEYQQYQD
Sbjct: 860 TGEGMDEMEFTEAESNMNDLVSEYQQYQD 946
>00276
          Length = 1330

 Score =  276 bits (707), Expect = 9e-75,   Method: Compositional matrix adjust.
 Identities = 133/355 (37%), Positives = 204/355 (57%), Gaps = 8/355 (2%)
 Frame = -3

Query: 78   SGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEAESCDCLQGFQXXX 137
            +G + Q+  P+  V G+  A NN+A+GHYT G ELVD VLD +RK A+ C  LQGF    
Sbjct: 1328 TGTYRQL-SPEQLVTGKEDAANNYARGHYTIGKELVDLVLDRIRKLADQCTGLQGFLIFH 1152

Query: 138  XXXXXXXXXXXXXXXXKIREEYPDRIMNTFSVVPSPKVSDTVVEPYNATLSVHQLVENTD 197
                            ++  +Y  +    F + P+P+VS  VVEPYN+ L+ H  +E++D
Sbjct: 1151 SFGGGTGSGFTSLXMERLSVDYGKKSKLEFXIYPAPQVSTAVVEPYNSILTTHTTLEHSD 972

Query: 198  ETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNM 257
              + +DNEA+YDIC R L +  PTY +LN L+   +S +T  LRF G LN DL +   N+
Sbjct: 971  CAFMVDNEAIYDICRRNLDIERPTYTNLNRLIXQIVSSITASLRFDGALNVDLTEFQTNL 792

Query: 258  VPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQVFDAKNMMAACDPRHGRYLTVAAVF 317
            VP+PR+HF +  +AP+ S     +  L V E+T   F+  N +  CDPRHG+Y+    ++
Sbjct: 791  VPYPRIHFPLATYAPVISAEKAYHEQLXVAEITNACFEPANQLVKCDPRHGKYMACCMLY 612

Query: 318  RGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPR--------GLKMAVTFIG 369
            RG +  K+V+  +  ++ K +  FV+W P   K  +   PP          ++ AV  + 
Sbjct: 611  RGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLS 432

Query: 370  NSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQ 424
            N+TAI E + R+  +F  M+ ++AF+HWY GEGM+E EF+EA  ++  L  +Y++
Sbjct: 431  NTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEE 267
>28905
          Length = 425

 Score =  256 bits (654), Expect(2) = 4e-69,   Method: Compositional matrix adjust.
 Identities = 122/129 (94%), Positives = 126/129 (97%), Gaps = 1/129 (0%)
 Frame = -1

Query: 253 LAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQVFDAKNMMAACDPRHGRYLT 312
           +AVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQ+FDAKNMMAACDPRHGRYLT
Sbjct: 389 VAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLT 210

Query: 313 VAAVFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMAVTFIGNST 372
           VAA+FRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKM+ TFIGNST
Sbjct: 209 VAAMFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSGTFIGNST 30

Query: 373 AIQ-ELFKR 380
           AIQ  LFKR
Sbjct: 29  AIQGRLFKR 3

 Score = 23.9 bits (50), Expect(2) = 4e-69,   Method: Composition-based stats.
 Identities = 9/9 (100%), Positives = 9/9 (100%)
 Frame = -2

Query: 242 FPGQLNADL 250
           FPGQLNADL
Sbjct: 424 FPGQLNADL 398
>31457
          Length = 1530

 Score =  248 bits (632), Expect = 4e-66,   Method: Compositional matrix adjust.
 Identities = 115/119 (96%), Positives = 118/119 (99%)
 Frame = +3

Query: 309 RYLTVAAVFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMAVTFI 368
           +YLTVAA+FRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKM+ TFI
Sbjct: 234 KYLTVAAMFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSSTFI 413

Query: 369 GNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQD 427
           GNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQD
Sbjct: 414 GNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQD 590
>25015
          Length = 458

 Score =  242 bits (618), Expect = 2e-64,   Method: Compositional matrix adjust.
 Identities = 112/115 (97%), Positives = 115/115 (100%)
 Frame = -3

Query: 20  FWEVISDEHGIDPTGTYHGDSDLQLDRISVYYNEATGGKYVPRAILVDLEPGTMDSVRSG 79
           FWEVISDEHGIDPTGTYHGDSDLQL+RI+VYYNEATGGKYVPRA+LVDLEPGTMDSVRSG
Sbjct: 363 FWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEATGGKYVPRAVLVDLEPGTMDSVRSG 184

Query: 80  PFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEAESCDCLQGFQ 134
           PFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEAESCDCLQGFQ
Sbjct: 183 PFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEAESCDCLQGFQ 19
>39157
          Length = 488

 Score =  227 bits (579), Expect(2) = 1e-63,   Method: Compositional matrix adjust.
 Identities = 111/127 (87%), Positives = 118/127 (92%), Gaps = 3/127 (2%)
 Frame = -1

Query: 1   MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLDRISVYYNEATGGKYV 60
           MREIVH+QAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQL+RI+VYYNEATGGKYV
Sbjct: 443 MREIVHLQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEATGGKYV 264

Query: 61  PRAILVDLEPGTMDSVRSG-PFG-QIFRPDNFVFGQSGAGNNWAKGHYTE-GAELVDSVL 117
           PRA+LVDLEPGTMDSVRSG PFG +IFRPDNFVFGQSGAGNNW +   T+ GAELVDSVL
Sbjct: 263 PRAVLVDLEPGTMDSVRSGSPFGPKIFRPDNFVFGQSGAGNNWGQKDTTQRGAELVDSVL 84

Query: 118 DVVRKEA 124
           DVVRK  
Sbjct: 83  DVVRKRG 63

 Score = 33.9 bits (76), Expect(2) = 1e-63,   Method: Compositional matrix adjust.
 Identities = 13/13 (100%), Positives = 13/13 (100%)
 Frame = -2

Query: 122 KEAESCDCLQGFQ 134
           KEAESCDCLQGFQ
Sbjct: 70  KEAESCDCLQGFQ 32
>12457
          Length = 781

 Score =  209 bits (532), Expect = 2e-54,   Method: Compositional matrix adjust.
 Identities = 99/239 (41%), Positives = 141/239 (58%)
 Frame = -1

Query: 65  LVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEA 124
           LVDLEP  +D VR+G + Q+F P+  V G+  A NN+A+GHYT G E+VD VLD +RK A
Sbjct: 718 LVDLEPTVVDEVRTGTYRQLFHPEQLVTGKEDAANNYARGHYTIGKEIVDLVLDRIRKLA 539

Query: 125 ESCDCLQGFQXXXXXXXXXXXXXXXXXXXKIREEYPDRIMNTFSVVPSPKVSDTVVEPYN 184
           + C  LQGF                    ++  +Y  +    F++ P+P+VS  VVEPYN
Sbjct: 538 DQCTGLQGFLIFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFAIYPAPQVSTAVVEPYN 359

Query: 185 ATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPG 244
           + L+ H  +E++D  + +DNEA+YDIC R L +  PTY +LN L+   +S +T  LRF G
Sbjct: 358 SILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLRFDG 179

Query: 245 QLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQVFDAKNMMAAC 303
            LN DL +   N+VP+PR+HF +  +AP+ S     +  LTV E+T   F+  N M  C
Sbjct: 178 ALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLTVAEITNACFEPANQMVKC 2
>05902
          Length = 1127

 Score =  152 bits (384), Expect = 3e-37,   Method: Compositional matrix adjust.
 Identities = 90/282 (31%), Positives = 158/282 (56%), Gaps = 12/282 (4%)
 Frame = +2

Query: 154 KIREEYPDRIMNTFSVVPS-PKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICF 212
           K+ + +P +++ T+SV P+  ++SD VV+PYN+ L++ +L +N D    +DN AL  I  
Sbjct: 74  KLNDRFPKKLIQTYSVFPNVDEISDVVVQPYNSLLTLKRLTQNADCVVVLDNTALNRIAA 253

Query: 213 RTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAP 272
             L + TPT+  +N LVS  MS  TT LR+PG +N DL  L  +++P PRLHF M G+ P
Sbjct: 254 DRLHIDTPTFAQVNQLVSTVMSTSTTTLRYPGYMNNDLIGLIASLIPTPRLHFLMTGYTP 433

Query: 273 LTSRGS-QQYRALTVPELTQQVFDAKNMMAACDPRHGR----YLTVAAVFRGRMSMKEVD 327
           LT+       R  TV ++ +++   KNMM +  P H +    Y+++  + +G +   +V 
Sbjct: 434 LTTDSQVANVRKTTVLDVMRRLLQPKNMMVST-PVHRQANHCYISILNIIQGEVDPTQVH 610

Query: 328 EQMLNVQNKNSSYFVEWIPNNVKTAVCDIPP---RGLKMAVTFIGNSTAIQELFKRISEQ 384
           + +  ++ +  + F+ W P +++ A+    P      +++   + N T+I  LF+RI  Q
Sbjct: 611 KSLQRIRERKLAQFIPWGPASIQVALSRKSPYVQTAHRVSGLMLANHTSISHLFERILRQ 790

Query: 385 FTAMFRRKAFLHWYTGEGM--DEM-EFTEAESNMNDLVSEYQ 423
           +  + +R+AF+  +  E +  D + EF  +   +  LV EYQ
Sbjct: 791 YDKLRKREAFMDQFKKEAIFKDNLDEFDNSREALQLLVDEYQ 916
>06360
          Length = 1896

 Score =  137 bits (344), Expect = 1e-32,   Method: Compositional matrix adjust.
 Identities = 69/179 (38%), Positives = 99/179 (55%), Gaps = 2/179 (1%)
 Frame = -1

Query: 1    MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQL--DRISVYYNEATGGK 58
            MRE + +  GQ G Q+G   WE+   EHGI P G    D  +    D  + +++E   GK
Sbjct: 1710 MRECISVHVGQAGVQMGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGK 1531

Query: 59   YVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLD 118
            +VPRA+ VDLEP  +D VR+G + Q+F P+  V G+  A NN+A+GHYT G E+VD VLD
Sbjct: 1530 HVPRAVFVDLEPTVVDEVRTGTYRQLFHPEQLVTGKEDAANNYARGHYTIGKEIVDLVLD 1351

Query: 119  VVRKEAESCDCLQGFQXXXXXXXXXXXXXXXXXXXKIREEYPDRIMNTFSVVPSPKVSD 177
             +RK A+ C  LQGF                    ++  +Y  +    F++ P+P+VSD
Sbjct: 1350 RIRKLADQCTGLQGFLIFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFAIYPAPQVSD 1174
>03702
          Length = 1932

 Score =  120 bits (302), Expect = 8e-28,   Method: Compositional matrix adjust.
 Identities = 59/140 (42%), Positives = 83/140 (59%), Gaps = 1/140 (0%)
 Frame = +1

Query: 167  FSVVPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLN 226
            F++ P+P+VS  VVEPYN+ L+ H  +E++D  + +DNEA+YDIC R L +  P Y +LN
Sbjct: 1501 FAIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPXYTNLN 1680

Query: 227  HLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPG-FAPLTSRGSQQYRALT 285
             L+   +S +T  LRF G LN DL +   N+VP P  H   PG   P+ S     +  LT
Sbjct: 1681 RLIGQIVSSITASLRFDGALNVDLTEFQTNLVPTP--HPLPPGHLCPVISAEKAYHEQLT 1854

Query: 286  VPELTQQVFDAKNMMAACDP 305
            V E+T   F+  N +  CDP
Sbjct: 1855 VAEVTNACFEPANQLVKCDP 1914
>17215
          Length = 632

 Score = 84.0 bits (206), Expect = 1e-16,   Method: Compositional matrix adjust.
 Identities = 38/117 (32%), Positives = 67/117 (57%), Gaps = 8/117 (6%)
 Frame = +3

Query: 316 VFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPP--------RGLKMAVTF 367
           ++RG +  K+V+  +  ++ K +  FV+W P   K  +   PP          ++ AV  
Sbjct: 6   LYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCM 185

Query: 368 IGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQ 424
           + N+TAI E + R+  +F  M+ ++AF+HWY GEGM+E EF+EA  ++  L  +Y++
Sbjct: 186 LSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEE 356
>29025
          Length = 395

 Score = 35.8 bits (81), Expect = 0.037,   Method: Compositional matrix adjust.
 Identities = 16/16 (100%), Positives = 16/16 (100%)
 Frame = -3

Query: 412 ESNMNDLVSEYQQYQD 427
           ESNMNDLVSEYQQYQD
Sbjct: 354 ESNMNDLVSEYQQYQD 307
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|9790237|ref|NP_062684.1| SMC1 structural maintenance
of chromosomes 1-like 1 [Mus musculus]
         (1233 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

08718                                                                 404   e-132
00063                                                                 105   9e-23
09495                                                                 100   4e-21
35107                                                                  98   3e-20
19618                                                                  33   0.50 
12308                                                                  31   2.9  
15478                                                                  31   3.3  
20290                                                                  30   5.7  
>08718
          Length = 1556

 Score =  404 bits (1039), Expect(2) = e-132,   Method: Compositional matrix adjust.
 Identities = 198/305 (64%), Positives = 254/305 (83%), Gaps = 3/305 (0%)
 Frame = +3

Query: 423 QKLREIEENQKRIEKLEEYITTSKQSLEEQKKLEGELTEEVEMAKRRIDEINKELNQVME 482
           QK +E+EEN+KRIEKL+EYI TS  + +EQ++ E +L+ EV  A  R++ I++EL+ + E
Sbjct: 114 QKDKEMEENKKRIEKLQEYIRTSTIAQQEQRESELQLSSEVGAASGRVESIDEELSGIQE 293

Query: 483 QLGDARIDRQESSRQQRKAEIMESIKRLYPGSVYGRLIDLCQPTQKKYQIAVTKVLGKNM 542
           QLG A++D+ ESSR  RKAE++E++KRL+PG V+GRLID C+P+ K+YQ+A+TKVLGK M
Sbjct: 294 QLGQAKVDKHESSRAVRKAELLENLKRLFPG-VHGRLIDQCEPSHKRYQVAITKVLGKYM 470

Query: 543 DAIIVDSEKTGRDCIQYIKEQRGEPETFLPLDYLEVKPTDEKLREL---KGAKLVIDVIR 599
           DAI+ DSEKT +DCIQY+KEQR EPETFLPLDYL V   +EKLR++   K  KLVIDVIR
Sbjct: 471 DAIVCDSEKTAKDCIQYMKEQRIEPETFLPLDYLHVTNVNEKLRDIQEPKNVKLVIDVIR 650

Query: 600 YEPPHIKKALQYACGNALVCDNVEDARRIAFGGHQRHKTVALDGTLFQKSGVISGGASDL 659
           Y+PP IKKAL +ACGNALVC++VEDARR+AF GH+RHK+VALDGTLFQKSGVISGGASDL
Sbjct: 651 YDPPVIKKALLFACGNALVCESVEDARRVAFAGHERHKSVALDGTLFQKSGVISGGASDL 830

Query: 660 KAKARRWDEKAVDKLKEKKGRLTEELKEQMKAKRKEAELRQVQSQAHGLQMRLKYSQSDL 719
           +AKARRWDEK +++LK +K +L EE KE +K +RKE+EL  V+SQ  GL+ RLKYSQ+DL
Sbjct: 831 RAKARRWDEKMLNQLKARKEKLMEERKEALKKQRKESELNTVRSQIKGLETRLKYSQNDL 1010

Query: 720 EQTKT 724
           E TK+
Sbjct: 1011ETTKS 1025

 Score = 85.9 bits (211), Expect(2) = e-132,   Method: Compositional matrix adjust.
 Identities = 42/85 (49%), Positives = 64/85 (75%)
 Frame = +2

Query: 742  ANFGPRINDIKRIIQSREREMKDLKEKMNQVEDEVFEEFCREIGVRNIREFEEEKVKRQN 801
             +F PR++++ R++  R  +++ LK+KMN+VEDEVF +FC  IGV NIR +EE +++ Q 
Sbjct: 1073 TSFDPRMDELDRMMSERGDDLRHLKDKMNRVEDEVFADFCTMIGVPNIRHYEERELRAQQ 1252

Query: 802  EIAKKRLEFENQKTRLGIQLDFEKN 826
            E AKKRL+FENQK +L  Q++ EK+
Sbjct: 1253 ERAKKRLDFENQKFKLQNQIECEKS 1327

 Score = 40.4 bits (93), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 20/40 (50%), Positives = 27/40 (67%)
 Frame = +2

Query: 207  DRYQRLKDEVVRAQVQLQLFKLYHNEVEIEKLNKELASKN 246
            +RYQRL +++   Q+ LQLFKL+   V +  L KELA KN
Sbjct: 1388 ERYQRLNEQLAEKQLHLQLFKLFTMNVRLTILRKELAKKN 1507
>00063
          Length = 499

 Score =  105 bits (263), Expect = 9e-23,   Method: Compositional matrix adjust.
 Identities = 64/141 (45%), Positives = 93/141 (65%)
 Frame = +2

Query: 290 ELNQKRPQYIKAKENTSHKIKKLEAAKKSLQHAQKHYKKRKGDMDELEKEMLSVEKAXXX 349
           ELN+KRP YIKAKE T+H  +K+E +++SL+ ++K ++  +  + E+E ++  VE++   
Sbjct: 65  ELNKKRPVYIKAKEKTTHMQRKVENSRRSLKQSRKKHENHEQIIREMEADLEQVEQSRQA 244

Query: 350 XXXXXXXXXXXXGRDLTLEENQVKKYHRLKEEASKRAATLAQELEKFNRDQKADQDRLDL 409
                       GR L LE++QV++Y+RLKEEA +RAA   QELE   R+QK+DQDR D 
Sbjct: 245 YEDRMEEESQSQGRSLQLEDSQVQQYNRLKEEAGRRAAKYMQELESITREQKSDQDRYDN 424

Query: 410 EERKKVETEAKIKQKLREIEE 430
           E RKK E  AKI+QK   IE+
Sbjct: 425 ELRKKNELLAKIQQKRDRIED 487
>09495
          Length = 1177

 Score =  100 bits (249), Expect = 4e-21,   Method: Compositional matrix adjust.
 Identities = 57/157 (36%), Positives = 86/157 (54%), Gaps = 14/157 (8%)
 Frame = -3

Query: 10   ENFKSYKGRQIIGPFQR-FTAIIGPNGSGKSNLMDAISFVLGEKTSNLRVKTLRDLIHGA 68
            ENFKSY G Q +GPF + FT+I+GPNGSGKSN++D++ FV G + + +R K +  LIH +
Sbjct: 1001 ENFKSYAGVQTLGPFHKSFTSIVGPNGSGKSNVIDSMLFVFGYRANKIRSKKVSVLIHNS 822

Query: 69   ----PVGKPAANRAFVSMVYSEEGAEDRTF---ARVIVG------GSSEYKINNKVVQLH 115
                 +G       F  +V +  G ++ T    ++++V        +S Y +N K     
Sbjct: 821  ENHRDMGSCCVAVHFQKIVDTGPGEDEYTVVPDSKIVVARTAFKDNTSSYSVNGKRATYK 642

Query: 116  EYSEELEKLGILIKARNFLVFQGAVESIAMKNPKERT 152
            E +  L   GI +    FL+ QG VE IAM  PK ++
Sbjct: 641  EVAALLRGSGIDLDHNRFLILQGEVEQIAMMKPKAQS 531
>35107
          Length = 679

 Score = 97.8 bits (242), Expect = 3e-20,   Method: Composition-based stats.
 Identities = 60/185 (32%), Positives = 103/185 (55%), Gaps = 1/185 (0%)
 Frame = +2

Query: 993  AQAEEEIKQEMNTLQQKLNERQSV-LQRIAAPNMKAMEKLESVRDKFQETSDEXXXXXXX 1051
            A  E    +  + L + + E++ + L R+A      ++++  VRDK ++  +E       
Sbjct: 50   AGGETRSDETQHGLHR*VQEKEELYLSRVAE-----LDQITEVRDKQRKYHEE------- 193

Query: 1052 XXXXXXXXXXIKKERFDRFNACFESVATNIDEIYKALSRNSSAQAFLGPENPEEPYLDGI 1111
                      ++K+R D F   F  +   + E+Y+ ++    A+  L   +  +P+ +GI
Sbjct: 194  ----------LRKQRLDEFMTGFAVITGKLKEMYQMITLGGDAELEL--VDSLDPFSEGI 337

Query: 1112 NYNCVAPGKRFRPMDNLSGGEKTVAALALLFAIHSYKPAPFFVLDEIDAALDNTNIGKVA 1171
             ++   P K ++ + NLSGGEKT+++LAL+FA+H YKP P +V+DEIDAALD  N+  VA
Sbjct: 338  VFSVRPPKKSWKNISNLSGGEKTLSSLALVFALHHYKPTPLYVMDEIDAALDFKNVSIVA 517

Query: 1172 NYIKE 1176
            NYIK+
Sbjct: 518  NYIKD 532
>19618
          Length = 974

 Score = 33.5 bits (75), Expect = 0.50,   Method: Composition-based stats.
 Identities = 21/52 (40%), Positives = 29/52 (55%)
 Frame = +2

Query: 1125 MDNLSGGEKTVAALALLFAIHSYKPAPFFVLDEIDAALDNTNIGKVANYIKE 1176
            +D LSGGEK   A+A LF    Y    F +LDE  +A+     GK+ +Y +E
Sbjct: 188  IDVLSGGEKQRIAMARLF----YHKPQFAILDECTSAVSVDVEGKMYSYCRE 331
>12308
          Length = 698

 Score = 31.2 bits (69), Expect = 2.9,   Method: Composition-based stats.
 Identities = 21/52 (40%), Positives = 27/52 (51%)
 Frame = -3

Query: 1125 MDNLSGGEKTVAALALLFAIHSYKPAPFFVLDEIDAALDNTNIGKVANYIKE 1176
            MD LSGGEK   A+A LF    Y    F +LDE  +A+     G +  Y +E
Sbjct: 153  MDVLSGGEKQRIAMARLF----YHKPQFAILDECTSAVSVDVEGFMYQYSRE 10
>15478
          Length = 1282

 Score = 30.8 bits (68), Expect = 3.3,   Method: Compositional matrix adjust.
 Identities = 18/100 (18%), Positives = 41/100 (41%), Gaps = 11/100 (11%)
 Frame = +1

Query: 71  GKPAANRAFVSMVYSEEGAEDRTFA-----------RVIVGGSSEYKINNKVVQLHEYSE 119
           G+    +A VS+ +  +  +                +V++GG ++Y IN      +   +
Sbjct: 55  GQAGVTKATVSITFDNQDKKQSPLGYEQYDEIVVTRQVVIGGRNKYLINGSNANNNRVQD 234

Query: 120 ELEKLGILIKARNFLVFQGAVESIAMKNPKERTALFEEIS 159
               + + +   +FL+ QG +  +    P E  ++ EE +
Sbjct: 235 LFRSVQLNVNNPHFLIMQGRITKVLNMKPPEILSMIEEAA 354
>20290
          Length = 1550

 Score = 30.0 bits (66), Expect = 5.7,   Method: Compositional matrix adjust.
 Identities = 17/38 (44%), Positives = 21/38 (55%)
 Frame = +3

Query: 1127 NLSGGEKTVAALALLFAIHSYKPAPFFVLDEIDAALDN 1164
            NLSGGE    AL L       KPA  +++DE  A LD+
Sbjct: 1044 NLSGGELQRVALVLCLG----KPADVYLIDEPSAYLDS 1145
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|117938334|ref|NP_033286.2| spectrin beta 2 isoform 2
[Mus musculus]
         (2154 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

19002                                                                 462   e-130
34010                                                                 162   3e-45
26578                                                                 180   5e-45
17613                                                                 108   8e-39
19147                                                                 128   5e-30
28965                                                                 105   2e-22
29446                                                                  90   9e-18
05733                                                                  72   2e-12
34417                                                                  69   2e-11
09711                                                                  65   4e-10
38533                                                                  64   7e-10
22703                                                                  60   8e-09
32371                                                                  41   2e-08
09100                                                                  54   5e-07
17567                                                                  50   9e-06
04951                                                                  45   2e-04
18202                                                                  44   8e-04
32088                                                                  37   0.061
18556                                                                  35   0.25 
>19002
          Length = 842

 Score =  462 bits (1190), Expect = e-130,   Method: Compositional matrix adjust.
 Identities = 216/280 (77%), Positives = 244/280 (87%)
 Frame = -2

Query: 71  DGRMLIKLLEVLSGERLPKPTKGRMRIHCLENVDKALQFLKEQRVHLENMGSHDIVDGNH 130
           DG+ML+KLLEV     +    KG+MRIHCLENVDKAL FL EQRVHLENMG+HDIVDG+ 
Sbjct: 841 DGKMLMKLLEVRVRGEIASDXKGKMRIHCLENVDKALTFLHEQRVHLENMGAHDIVDGSS 662

Query: 131 RLTLGLIWTIILRFQIQDISVETEDNKEKKSAKDALLLWCQMKTAGYPNVNIHNFTTSWR 190
           RLTLGLIWTIILRFQIQDI +E  DN E KSAKDALLLWCQMKTAGYPNVN+ NFTTSWR
Sbjct: 661 RLTLGLIWTIILRFQIQDIMIEEVDNSETKSAKDALLLWCQMKTAGYPNVNVRNFTTSWR 482

Query: 191 DGMAFNALIHKHRPDLIDFDKLKKSNAHYNLQNAFNLAEQHLGLTKLLDPEDISVDHPDE 250
           DG+AFNA+IHKHRPDL+ +D+L KS+A  NLQNAF +AE  LGLT LL+PED++V++PDE
Sbjct: 481 DGLAFNAIIHKHRPDLVQYDRLHKSSAIQNLQNAFTVAEDKLGLTALLEPEDVNVEYPDE 302

Query: 251 KSIITYVVTYYHYFSKMKALAVEGKRIGKVLDNAIETEKMIEKYESLASDLLEWIEQTII 310
           KSIITYVVTYYHYFSKMKA +V+GKRIGKV+DNAI TE  IE+YE+L SDLLEWIEQTI+
Sbjct: 301 KSIITYVVTYYHYFSKMKADSVQGKRIGKVIDNAINTENSIEEYETLTSDLLEWIEQTIV 122

Query: 311 ILNNRKFANSLVGVQQQLQAFNTYRTVEKPPKFTEKGNLE 350
           IL +R+FANSL GVQQQL AFNTYR VEKPPKF EKGNLE
Sbjct: 121 ILRDRQFANSLTGVQQQLAAFNTYRIVEKPPKFDEKGNLE 2
>34010
          Length = 832

 Score =  162 bits (411), Expect(2) = 3e-45,   Method: Compositional matrix adjust.
 Identities = 76/119 (63%), Positives = 97/119 (81%)
 Frame = +3

Query: 1926 KPRDVSSVELLMNNHQGIKAEIDARNDSFTACIELGKSLLARKHYASEEIKEKLLQLTEK 1985
            KPRDVS VELLMNNHQ +KAEIDAR ++F  CI LG+ LL RKHY  EE++EKL+QLT +
Sbjct: 84   KPRDVSGVELLMNNHQSLKAEIDAREENFAICINLGRDLLNRKHYRQEEVREKLIQLTLE 263

Query: 1986 RKEMIDKWEDRWEWLRLILEVHQFSRDASVAEAWLLGQEPYLSSREIGQSVDEVEKLIK 2044
            R +M D W+DRWE L+LILEV+QF+RDA+VAEAWL+ QE Y  ++++G ++D VE LIK
Sbjct: 264  RLDMTDLWKDRWEHLQLILEVYQFARDAAVAEAWLVAQEQYFLNQDLGDTLDAVENLIK 440

 Score = 40.0 bits (92), Expect(2) = 3e-45,   Method: Compositional matrix adjust.
 Identities = 16/30 (53%), Positives = 20/30 (66%)
 Frame = +1

Query: 1898 GDKFRFFSMVRDLMLWMEDVIRQIEAQEKP 1927
             D +RF  M  DL LWM+D+IRQ+  QE P
Sbjct: 1    SDFYRFMLMAHDLHLWMDDIIRQMNTQENP 90

 Score = 41.2 bits (95), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 34/134 (25%), Positives = 61/134 (45%), Gaps = 4/134 (2%)
 Frame = +3

Query: 1078 PNTLTEAEKLLTQHENIKNEIDNYEEDYQKMRDMGEMVTQG----QTDAQYMFLRQRLQA 1133
            P  ++  E L+  H+++K EID  EE++    ++G  +       Q + +   ++  L+ 
Sbjct: 87   PRDVSGVELLMNNHQSLKAEIDAREENFAICINLGRDLLNRKHYRQEEVREKLIQLTLER 266

Query: 1134 LDTGWNELHKMWENRQNLLSQSHAYQQFLRDTKQAEAFLNNQEYVLAHTEMPTTLEGAEA 1193
            LD     +  +W++R   L       QF RD   AEA+L  QE    + ++  TL+  E 
Sbjct: 267  LD-----MTDLWKDRWEHLQLILEVYQFARDAAVAEAWLVAQEQYFLNQDLGDTLDAVEN 431

Query: 1194 AIKKQEDFMTTMDA 1207
             IK  +   +   A
Sbjct: 432  LIKSMKPLKSCCHA 473

 Score = 33.9 bits (76), Expect = 0.70,   Method: Compositional matrix adjust.
 Identities = 25/122 (20%), Positives = 57/122 (46%)
 Frame = +3

Query: 655 KDLTSVMRLLSKHRAFEDEMSGRSGHFEQAIKEGEDMIAEEHFGSXXXXXXXXXXXXQWA 714
           +D++ V  L++ H++ + E+  R  +F   I  G D++  +H+              +  
Sbjct: 90  RDVSGVELLMNNHQSLKAEIDAREENFAICINLGRDLLNRKHYRQEEVREKLIQLTLERL 269

Query: 715 NLEQLSAIRKKRLEEASLLHQFQADADDIDAWMLDILKIVSSNDVGHDEYSTQSLVKKHK 774
           ++  L   R + L+    ++QF  DA   +AW++   +   + D+G    + ++L+K  K
Sbjct: 270 DMTDLWKDRWEHLQLILEVYQFARDAAVAEAWLVAQEQYFLNQDLGDTLDAVENLIKSMK 449

Query: 775 DV 776
            +
Sbjct: 450 PL 455

 Score = 31.6 bits (70), Expect = 3.2,   Method: Compositional matrix adjust.
 Identities = 28/133 (21%), Positives = 60/133 (45%), Gaps = 7/133 (5%)
 Frame = +3

Query: 1503 NLQTVQLLIKKNQTLQKEIQGHQPRIDDIFERSQNIITDSSSLNAEAIRQRLA------- 1555
            ++  V+LL+  +Q+L+ EI   +          ++++ +      E +R++L        
Sbjct: 93   DVSGVELLMNNHQSLKAEIDAREENFAICINLGRDLL-NRKHYRQEEVREKLIQLTLERL 269

Query: 1556 DLKQLWGLLIEETEKRHRRLEEAHKAQQYYFDAAEAEAWMSEQELYMMSEEKAKDEQSAV 1615
            D+  LW       + R   L+   +  Q+  DAA AEAW+  QE Y ++++      +  
Sbjct: 270  DMTDLW-------KDRWEHLQLILEVYQFARDAAVAEAWLVAQEQYFLNQDLGDTLDAVE 428

Query: 1616 SMLKKHQILEQAV 1628
            +++K  + L+   
Sbjct: 429  NLIKSMKPLKSCC 467
>26578
          Length = 430

 Score =  180 bits (457), Expect = 5e-45,   Method: Compositional matrix adjust.
 Identities = 84/133 (63%), Positives = 111/133 (83%)
 Frame = +1

Query: 1676 ERRGKLDERHRLFQLNREVDDLEQWIAEREVVAGSHELGQDYEHVTMLQERFREFARDTG 1735
            ERRGKL+E  +L+ L+RE+ DL QWIAE+ +VAGS++ GQDYEHV+ML+E+F+EFARDT 
Sbjct: 1    ERRGKLEEVFKLYTLHREIYDLLQWIAEKSLVAGSNDPGQDYEHVSMLKEQFKEFARDTE 180

Query: 1736 NIGQERVDTVNNMADELINSGHSDAATIAEWKDGLNEAWADLLELIDTRTQILAASYELH 1795
            ++GQERV + N + D+LI   HSD+A+IAEWKD +NEAWADLLELIDTRTQ+L +S+ELH
Sbjct: 181  SMGQERVASANEICDQLIALDHSDSASIAEWKDNVNEAWADLLELIDTRTQLLQSSWELH 360

Query: 1796 KFYHDAKEIFGRI 1808
            KF ++ K+   RI
Sbjct: 361  KFLYECKDTLERI 399

 Score = 45.8 bits (107), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 31/128 (24%), Positives = 56/128 (43%), Gaps = 1/128 (0%)
 Frame = +1

Query: 828 RKQALQDTLALYKMFSEADACELWIDEKEQWLNNMQIPEKLEDLEVIQHRFESLEPEMNN 887
           R+  L++   LY +  E      WI EK     +    +  E + +++ +F+    +  +
Sbjct: 4   RRGKLEEVFKLYTLHREIYDLLQWIAEKSLVAGSNDPGQDYEHVSMLKEQFKEFARDTES 183

Query: 888 QAS-RVAVVNQIARQLMHNGHPSEKEIRAQQDKLNTRWSQFRELVDRKKDALLSALSIQN 946
               RVA  N+I  QL+   H     I   +D +N  W+   EL+D +   L S+  +  
Sbjct: 184 MGQERVASANEICDQLIALDHSDSASIAEWKDNVNEAWADLLELIDTRTQLLQSSWELHK 363

Query: 947 YHLECNET 954
           +  EC +T
Sbjct: 364 FLYECKDT 387

 Score = 33.1 bits (74), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 30/127 (23%), Positives = 55/127 (43%), Gaps = 4/127 (3%)
 Frame = +1

Query: 723 RKKRLEEASLLHQFQADADDIDAWMLDILKIVSSNDVGHDEYSTQSLVKKHKDVAEEITN 782
           R+ +LEE   L+    +  D+  W+ +   +  SND G D      L ++ K+ A +  +
Sbjct: 4   RRGKLEEVFKLYTLHREIYDLLQWIAEKSLVAGSNDPGQDYEHVSMLKEQFKEFARDTES 183

Query: 783 YR----PTIDTLHEQASALPQAHAESPDVKGRLAGIEERCKEMAELTRLRKQALQDTLAL 838
                  + + + +Q  AL   H++S  +      + E   ++ EL   R Q LQ +  L
Sbjct: 184 MGQERVASANEICDQLIALD--HSDSASIAEWKDNVNEAWADLLELIDTRTQLLQSSWEL 357

Query: 839 YKMFSEA 845
           +K   E 
Sbjct: 358 HKFLYEC 378

 Score = 31.6 bits (70), Expect = 3.7,   Method: Compositional matrix adjust.
 Identities = 28/104 (26%), Positives = 44/104 (42%), Gaps = 1/104 (0%)
 Frame = +1

Query: 640 WIREKEKILSSDDYGKDLTSVMRLLSKHRAF-EDEMSGRSGHFEQAIKEGEDMIAEEHFG 698
           WI EK  +  S+D G+D   V  L  + + F  D  S        A +  + +IA +H  
Sbjct: 73  WIAEKSLVAGSNDPGQDYEHVSMLKEQFKEFARDTESMGQERVASANEICDQLIALDHSD 252

Query: 699 SXXXXXXXXXXXXQWANLEQLSAIRKKRLEEASLLHQFQADADD 742
           S             WA+L +L   R + L+ +  LH+F  +  D
Sbjct: 253 SASIAEWKDNVNEAWADLLELIDTRTQLLQSSWELHKFLYECKD 384
>17613
          Length = 1108

 Score =  108 bits (269), Expect(2) = 8e-39,   Method: Compositional matrix adjust.
 Identities = 54/132 (40%), Positives = 78/132 (59%), Gaps = 1/132 (0%)
 Frame = +3

Query: 222 QNAFNLAEQHLGLTKLLDPED-ISVDHPDEKSIITYVVTYYHYFSKMKALAVEGKRIGKV 280
           Q+ F    +HL + ++LDPED ++   PDE+S++ YV +YYH FS  +       RI KV
Sbjct: 366 QHCF*HRRKHLDIPRMLDPEDMVNSAKPDERSVMAYVSSYYHAFSGAQQAETAANRICKV 545

Query: 281 LDNAIETEKMIEKYESLASDLLEWIEQTIIILNNRKFANSLVGVQQQLQAFNTYRTVEKP 340
           L    E E+++E+YE LASDLLEWI +T   L NR   N+L G + +L  F  YR  +KP
Sbjct: 546 LKVNQENERLMEEYERLASDLLEWIRRTRPWLENRVTDNTLPGTRHKLDEFRDYRRKQKP 725

Query: 341 PKFTEKGNLEVL 352
           P +  + +   L
Sbjct: 726 PSWRTRPSWRTL 761

 Score = 73.2 bits (178), Expect(2) = 8e-39,   Method: Composition-based stats.
 Identities = 49/144 (34%), Positives = 71/144 (49%), Gaps = 9/144 (6%)
 Frame = +1

Query: 95  MRIHCLENVDKALQFLKEQRVHLENMGSHDIVDGNHRLTLGLIWTIILRFQIQDISVETE 154
           MR H + NV+KAL ++  QR             G HR           R +  DI  + +
Sbjct: 4   MRFHKIANVNKALDYIDLQRGQ----------TGLHRSRRN-----C*RQRKDDIRYDLD 138

Query: 155 D---------NKEKKSAKDALLLWCQMKTAGYPNVNIHNFTTSWRDGMAFNALIHKHRPD 205
           +         +  +   +   ++    KTA Y NVN+ NF  S++DG+AF ALIH+HRP+
Sbjct: 139 NYPQVCHPRHHSRRTHCQRRTVIVVPAKTAPYKNVNVQNFHLSFKDGLAFCALIHRHRPE 318

Query: 206 LIDFDKLKKSNAHYNLQNAFNLAE 229
           LID+  L K N   NL  AF++AE
Sbjct: 319 LIDYHSLSKDNPLENLNTAFDIAE 390

 Score = 81.3 bits (199), Expect = 4e-15,   Method: Compositional matrix adjust.
 Identities = 46/119 (38%), Positives = 71/119 (59%), Gaps = 1/119 (0%)
 Frame = +2

Query: 341 PKFTEKGNLEVLLFTIQSKMRANNQKVYMPREGKLISDINKAWERLEKAEHERELALRNE 400
           PK  +K  LE    T+Q+++R +N+  Y+P EGK++SDI  AW+ LE AE   E  L +E
Sbjct: 725 PKLEDKAKLENSFNTLQTRLRLSNRPAYLPTEGKMVSDIANAWKGLEHAEKGFEEWLLSE 904

Query: 401 LIRQEKLEQLARRFDRKAAMRETWLSENQRLVSQDNFG-FDLPAVEAATKKHEAIETDI 458
           L R E+L+ LA++F  K  + E W    + ++   +F    L  ++A  KKHEA E+D+
Sbjct: 905 LQRLERLDHLAQKFRHKCEIHEEWSQGKEDMLQSRDFKQCRLNELKAMKKKHEAFESDL 1081

 Score = 33.1 bits (74), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 18/53 (33%), Positives = 29/53 (54%), Gaps = 1/53 (1%)
 Frame = +2

Query: 2008 QFSRDASVAEAWLLGQEPYLSSREIGQS-VDEVEKLIKRHEAFEKSAATWDER 2059
            +F     + E W  G+E  L SR+  Q  ++E++ + K+HEAFE   A   +R
Sbjct: 941  KFRHKCEIHEEWSQGKEDMLQSRDFKQCRLNELKAMKKKHEAFESDLAAHQDR 1099
>19147
          Length = 474

 Score =  128 bits (321), Expect(2) = 5e-30,   Method: Compositional matrix adjust.
 Identities = 59/107 (55%), Positives = 80/107 (74%)
 Frame = +1

Query: 108 QFLKEQRVHLENMGSHDIVDGNHRLTLGLIWTIILRFQIQDISVETEDNKEKKSAKDALL 167
            ++  + V L ++G+ +IVDGN ++TLG+IWTIILRF IQDI+VE      + +AK+ LL
Sbjct: 46  SYIASKGVKLVSIGAEEIVDGNVKMTLGMIWTIILRFAIQDITVE------ELTAKEGLL 207

Query: 168 LWCQMKTAGYPNVNIHNFTTSWRDGMAFNALIHKHRPDLIDFDKLKK 214
           LWCQ KTA Y NVN+ NF  S++DG+AF ALIH+HRP+LID+  L K
Sbjct: 208 LWCQRKTAPYKNVNVQNFHLSFKDGLAFCALIHRHRPELIDYHSLSK 348

 Score = 23.5 bits (49), Expect(2) = 5e-30,   Method: Compositional matrix adjust.
 Identities = 10/21 (47%), Positives = 15/21 (71%)
 Frame = +3

Query: 94  RMRIHCLENVDKALQFLKEQR 114
           +MR H + NV+KAL+  + QR
Sbjct: 3   KMRFHKIANVNKALELHRLQR 65
>28965
          Length = 421

 Score =  105 bits (262), Expect = 2e-22,   Method: Compositional matrix adjust.
 Identities = 57/141 (40%), Positives = 90/141 (63%)
 Frame = +2

Query: 882  EPEMNNQASRVAVVNQIARQLMHNGHPSEKEIRAQQDKLNTRWSQFRELVDRKKDALLSA 941
            + ++ N   +V  VN +A QL+ +GHP E+ IR +Q+++N  W + R+L   +++ L  A
Sbjct: 2    QKDLQNHEDKVVEVNTLAEQLVTDGHPEEETIRQKQEEVNEAWKRLRQLSLLRQERLYGA 181

Query: 942  LSIQNYHLECNETKSWIREKTKVIESTQDLGNDLAGVMALQRKLTGMERDLVAIEAKLSD 1001
              IQ ++ + +ET +WI+EK  V+ ST D G DLA V  LQRK  G+ERDL A+E K++ 
Sbjct: 182  HEIQRFNRDADETIAWIQEKDAVL-STDDYGRDLASVQTLQRKHEGVERDLAALEEKVNA 358

Query: 1002 LQKEAEKLESEHPDQAQAILS 1022
            L  E+ +L+  H DQ++ I S
Sbjct: 359  LGTESVRLQGIHGDQSEQIHS 421

 Score = 76.6 bits (187), Expect = 9e-14,   Method: Compositional matrix adjust.
 Identities = 47/132 (35%), Positives = 78/132 (59%), Gaps = 1/132 (0%)
 Frame = +2

Query: 1739 QERVDTVNNMADELINSGHSDAATIAEWKDGLNEAWADLLELIDTRTQILAASYELHKFY 1798
            +++V  VN +A++L+  GH +  TI + ++ +NEAW  L +L   R + L  ++E+ +F 
Sbjct: 23   EDKVVEVNTLAEQLVTDGHPEEETIRQKQEEVNEAWKRLRQLSLLRQERLYGAHEIQRFN 202

Query: 1799 HDAKEIFGRIQDKHKKLP-EELGRDQNTVETLQRMHTTFEHDIQALGTQVRQLQEDAARL 1857
             DA E    IQ+K   L  ++ GRD  +V+TLQR H   E D+ AL  +V  L  ++ RL
Sbjct: 203  RDADETIAWIQEKDAVLSTDDYGRDLASVQTLQRKHEGVERDLAALEEKVNALGTESVRL 382

Query: 1858 QAAYAGDKADDI 1869
            Q  + GD+++ I
Sbjct: 383  QGIH-GDQSEQI 415

 Score = 53.9 bits (128), Expect = 8e-07,   Method: Compositional matrix adjust.
 Identities = 37/139 (26%), Positives = 75/139 (53%)
 Frame = +2

Query: 1518 QKEIQGHQPRIDDIFERSQNIITDSSSLNAEAIRQRLADLKQLWGLLIEETEKRHRRLEE 1577
            QK++Q H+ ++ ++   ++ ++TD      E IRQ+  ++ + W  L + +  R  RL  
Sbjct: 2    QKDLQNHEDKVVEVNTLAEQLVTDGHP-EEETIRQKQEEVNEAWKRLRQLSLLRQERLYG 178

Query: 1578 AHKAQQYYFDAAEAEAWMSEQELYMMSEEKAKDEQSAVSMLKKHQILEQAVEDYAETVHQ 1637
            AH+ Q++  DA E  AW+ E++  + +++  +D  S  ++ +KH+ +E+ +    E V+ 
Sbjct: 179  AHEIQRFNRDADETIAWIQEKDAVLSTDDYGRDLASVQTLQRKHEGVERDLAALEEKVNA 358

Query: 1638 LSKTSRALVADSHPESERI 1656
            L   S  L      +SE+I
Sbjct: 359  LGTESVRLQGIHGDQSEQI 415

 Score = 52.8 bits (125), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 32/119 (26%), Positives = 65/119 (54%)
 Frame = +2

Query: 1628 VEDYAETVHQLSKTSRALVADSHPESERISMRQSKVDKLYAGLKDLAEERRGKLDERHRL 1687
            ++++ + V +++  +  LV D HPE E I  +Q +V++ +  L+ L+  R+ +L   H +
Sbjct: 11   LQNHEDKVVEVNTLAEQLVTDGHPEEETIRQKQEEVNEAWKRLRQLSLLRQERLYGAHEI 190

Query: 1688 FQLNREVDDLEQWIAEREVVAGSHELGQDYEHVTMLQERFREFARDTGNIGQERVDTVN 1746
             + NR+ D+   WI E++ V  + + G+D   V  LQ +     RD   + +E+V+ + 
Sbjct: 191  QRFNRDADETIAWIQEKDAVLSTDDYGRDLASVQTLQRKHEGVERDLAAL-EEKVNALG 364

 Score = 52.4 bits (124), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 28/94 (29%), Positives = 51/94 (54%)
 Frame = +2

Query: 713 WANLEQLSAIRKKRLEEASLLHQFQADADDIDAWMLDILKIVSSNDVGHDEYSTQSLVKK 772
           W  L QLS +R++RL  A  + +F  DAD+  AW+ +   ++S++D G D  S Q+L +K
Sbjct: 128 WKRLRQLSLLRQERLYGAHEIQRFNRDADETIAWIQEKDAVLSTDDYGRDLASVQTLQRK 307

Query: 773 HKDVAEEITNYRPTIDTLHEQASALPQAHAESPD 806
           H+ V  ++      ++ L  ++  L   H +  +
Sbjct: 308 HEGVERDLAALEEKVNALGTESVRLQGIHGDQSE 409

 Score = 49.7 bits (117), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 32/114 (28%), Positives = 53/114 (46%)
 Frame = +2

Query: 563 DIAIQAERVRGVNASAQKFATDGEGYKPCDPQVIRDRVAHMEFCYQELCQXXXXXXXXXX 622
           D+    ++V  VN  A++  TDG      + + IR +   +   ++ L Q          
Sbjct: 8   DLQNHEDKVVEVNTLAEQLVTDGH----PEEETIRQKQEEVNEAWKRLRQLSLLRQERLY 175

Query: 623 XXXXXWKFFWEMAEEEGWIREKEKILSSDDYGKDLTSVMRLLSKHRAFEDEMSG 676
                 +F  +  E   WI+EK+ +LS+DDYG+DL SV  L  KH   E +++ 
Sbjct: 176 GAHEIQRFNRDADETIAWIQEKDAVLSTDDYGRDLASVQTLQRKHEGVERDLAA 337

 Score = 49.3 bits (116), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 29/83 (34%), Positives = 49/83 (59%), Gaps = 2/83 (2%)
 Frame = +2

Query: 378 DINKAWERLEKAEHERELALRNELIRQEKL--EQLARRFDRKAAMRETWLSENQRLVSQD 435
           ++N+AW+RL      R+L+L    +RQE+L      +RF+R A     W+ E   ++S D
Sbjct: 113 EVNEAWKRL------RQLSL----LRQERLYGAHEIQRFNRDADETIAWIQEKDAVLSTD 262

Query: 436 NFGFDLPAVEAATKKHEAIETDI 458
           ++G DL +V+   +KHE +E D+
Sbjct: 263 DYGRDLASVQTLQRKHEGVERDL 331

 Score = 47.0 bits (110), Expect = 9e-05,   Method: Compositional matrix adjust.
 Identities = 23/105 (21%), Positives = 59/105 (56%)
 Frame = +2

Query: 1326 QLISEKPETEAVVKEKLTGLHKMWEVLESTTQTKAQRLFDANKAELFTQSCADLDKWLHG 1385
            QL+++    E  +++K   +++ W+ L   +  + +RL+ A++ + F +   +   W+  
Sbjct: 59   QLVTDGHPEEETIRQKQEEVNEAWKRLRQLSLLRQERLYGAHEIQRFNRDADETIAWIQE 238

Query: 1386 LESQIQSDDYGKDLTSVNILLKKQQMLENQMEVRKKEIEELQSQA 1430
             ++ + +DDYG+DL SV  L +K + +E  +   ++++  L +++
Sbjct: 239  KDAVLSTDDYGRDLASVQTLQRKHEGVERDLAALEEKVNALGTES 373

 Score = 44.7 bits (104), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 23/83 (27%), Positives = 49/83 (59%), Gaps = 3/83 (3%)
 Frame = +2

Query: 1464 RKHNLLASKEIHQFNRDVEDEILWVGERMPLATSTDHGHNLQTVQLLIKKNQTLQKEIQG 1523
            R+  L  + EI +FNRD ++ I W+ E+  + ++ D+G +L +VQ L +K++ +++++  
Sbjct: 158  RQERLYGAHEIQRFNRDADETIAWIQEKDAVLSTDDYGRDLASVQTLQRKHEGVERDLAA 337

Query: 1524 HQPRIDDIFERS---QNIITDSS 1543
             + +++ +   S   Q I  D S
Sbjct: 338  LEEKVNALGTESVRLQGIHGDQS 406

 Score = 42.0 bits (97), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 28/116 (24%), Positives = 63/116 (54%), Gaps = 1/116 (0%)
 Frame = +2

Query: 989  ERDLVAIEAKLSDLQKEAEKLESE-HPDQAQAILSRLAEISDVWEEMKTTLKNREASLGE 1047
            ++DL   E K+ ++   AE+L ++ HP++ + I  +  E+++ W+ ++     R+  L  
Sbjct: 2    QKDLQNHEDKVVEVNTLAEQLVTDGHPEE-ETIRQKQEEVNEAWKRLRQLSLLRQERLYG 178

Query: 1048 ASKLQQFLRDLDDFQSWLSRTQTAIASEDMPNTLTEAEKLLTQHENIKNEIDNYEE 1103
            A ++Q+F RD D+  +W+      ++++D    L   + L  +HE ++ ++   EE
Sbjct: 179  AHEIQRFNRDADETIAWIQEKDAVLSTDDYGRDLASVQTLQRKHEGVERDLAALEE 346

 Score = 41.6 bits (96), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 30/111 (27%), Positives = 54/111 (48%)
 Frame = +2

Query: 1952 DSFTACIELGKSLLARKHYASEEIKEKLLQLTEKRKEMIDKWEDRWEWLRLILEVHQFSR 2011
            D       L + L+   H   E I++K  ++ E  K +      R E L    E+ +F+R
Sbjct: 26   DKVVEVNTLAEQLVTDGHPEEETIRQKQEEVNEAWKRLRQLSLLRQERLYGAHEIQRFNR 205

Query: 2012 DASVAEAWLLGQEPYLSSREIGQSVDEVEKLIKRHEAFEKSAATWDERFSA 2062
            DA    AW+  ++  LS+ + G+ +  V+ L ++HE  E+  A  +E+ +A
Sbjct: 206  DADETIAWIQEKDAVLSTDDYGRDLASVQTLQRKHEGVERDLAALEEKVNA 358

 Score = 40.8 bits (94), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 32/129 (24%), Positives = 64/129 (49%), Gaps = 1/129 (0%)
 Frame = +2

Query: 1095 KNEIDNYEEDYQKMRDMGE-MVTQGQTDAQYMFLRQRLQALDTGWNELHKMWENRQNLLS 1153
            + ++ N+E+   ++  + E +VT G  + +   +RQ+ + ++  W  L ++   RQ  L 
Sbjct: 2    QKDLQNHEDKVVEVNTLAEQLVTDGHPEEET--IRQKQEEVNEAWKRLRQLSLLRQERLY 175

Query: 1154 QSHAYQQFLRDTKQAEAFLNNQEYVLAHTEMPTTLEGAEAAIKKQEDFMTTMDANEEKIN 1213
             +H  Q+F RD  +  A++  ++ VL+  +    L   +   +K E     + A EEK+N
Sbjct: 176  GAHEIQRFNRDADETIAWIQEKDAVLSTDDYGRDLASVQTLQRKHEGVERDLAALEEKVN 355

Query: 1214 AVVETGRRL 1222
            A+     RL
Sbjct: 356  ALGTESVRL 382

 Score = 37.0 bits (84), Expect = 0.078,   Method: Compositional matrix adjust.
 Identities = 31/122 (25%), Positives = 66/122 (54%), Gaps = 2/122 (1%)
 Frame = +2

Query: 1208 NEEKINAVVETGRRLVSDGNINSDRIQEKVDSIDDRHRKNREAASELLMRLKDNRDLQKF 1267
            +E+K+  V     +LV+DG+   + I++K + +++  ++ R+ +     RL    ++Q+F
Sbjct: 20   HEDKVVEVNTLAEQLVTDGHPEEETIRQKQEEVNEAWKRLRQLSLLRQERLYGAHEIQRF 199

Query: 1268 LQDCQELSLWINEK--MLTAQDMSYDEARNLHSKWLKHQAFMAELASNKEWLDKIEKEGM 1325
             +D  E   WI EK  +L+  D   D A ++ +   KH+    +LA+ +E ++ +  E +
Sbjct: 200  NRDADETIAWIQEKDAVLSTDDYGRDLA-SVQTLQRKHEGVERDLAALEEKVNALGTESV 376

Query: 1326 QL 1327
            +L
Sbjct: 377  RL 382

 Score = 37.0 bits (84), Expect = 0.097,   Method: Compositional matrix adjust.
 Identities = 23/89 (25%), Positives = 45/89 (50%)
 Frame = +2

Query: 1869 IQKRENEVLEAWKSLLDACEGRRVRLVDTGDKFRFFSMVRDLMLWMEDVIRQIEAQEKPR 1928
            I++++ EV EAWK L      R+ RL    +  RF     + + W+++    +   +  R
Sbjct: 95   IRQKQEEVNEAWKRLRQLSLLRQERLYGAHEIQRFNRDADETIAWIQEKDAVLSTDDYGR 274

Query: 1929 DVSSVELLMNNHQGIKAEIDARNDSFTAC 1957
            D++SV+ L   H+G++ ++ A  +   A 
Sbjct: 275  DLASVQTLQRKHEGVERDLAALEEKVNAL 361

 Score = 35.0 bits (79), Expect = 0.33,   Method: Compositional matrix adjust.
 Identities = 18/65 (27%), Positives = 34/65 (52%)
 Frame = +2

Query: 517 LQKIFQEMLYIMDWMDEMKVLLLSQDYGKHLLGVEDLLQKHALVEADIAIQAERVRGVNA 576
           +Q+  ++    + W+ E   +L + DYG+ L  V+ L +KH  VE D+A   E+V  +  
Sbjct: 188 IQRFNRDADETIAWIQEKDAVLSTDDYGRDLASVQTLQRKHEGVERDLAALEEKVNALGT 367

Query: 577 SAQKF 581
            + + 
Sbjct: 368 ESVRL 382
>29446
          Length = 1445

 Score = 90.1 bits (222), Expect = 9e-18,   Method: Compositional matrix adjust.
 Identities = 56/139 (40%), Positives = 78/139 (56%), Gaps = 5/139 (3%)
 Frame = +3

Query: 42   VQKKTFTKWVNSHLARVSCRITDLYTDLRDGRMLIKLLEVLSGERLPKPTK-GRMRIHCL 100
            +QK TFT+W N HL  V+  I DL +D  DG  L+ L+EVLSG++     K    R   L
Sbjct: 999  IQKNTFTRWANEHLRTVNKAIADLESDFSDGLRLVALIEVLSGKKFKHVNKRPNFRTQKL 1178

Query: 101  ENVDKALQFLK-EQRVHLENMGSHDIVDGNHRLTLGLIWTIILRFQIQDISVETED---N 156
            ENV   L+FL+ ++ + + N+ S DIVD   +L LGLIWT+IL + I     E E+   +
Sbjct: 1179 ENVTLTLKFLEDDEGIRIVNIDSTDIVDKKLKLILGLIWTLILHYSISMPMWEGEEPTPS 1358

Query: 157  KEKKSAKDALLLWCQMKTA 175
            +   + K  LL W Q K  
Sbjct: 1359 EGGPTPKQRLLNWIQSKVP 1415
>05733
          Length = 1021

 Score = 72.4 bits (176), Expect = 2e-12,   Method: Composition-based stats.
 Identities = 38/103 (36%), Positives = 61/103 (59%), Gaps = 3/103 (2%)
 Frame = +2

Query: 165 ALLLWCQ--MKTAGYPNVNIHNFTTSWRDGMAFNALIHKHRPDLIDFDKLKKSNAHYNLQ 222
           +LL WCQ  +    Y  V+I +FT+SWR G+AF ALIH  RP LI    L +     N Q
Sbjct: 467 SLLRWCQRVLNXGTYRGVHIIDFTSSWRSGLAFCALIHAFRPHLISPASLMECETVKNNQ 646

Query: 223 NAFNLAEQHLGLTKLLDPEDISV-DHPDEKSIITYVVTYYHYF 264
            AF++A++ LG+  ++  ED++    PD+ +++ Y+  ++  F
Sbjct: 647 LAFDVAQKELGIAPVMRGEDMAACAVPDKLTMVAYLSQFHELF 775
>34417
          Length = 1096

 Score = 69.3 bits (168), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 32/77 (41%), Positives = 49/77 (63%), Gaps = 1/77 (1%)
 Frame = +2

Query: 186 TTSWRDGMAFNALIHKHRPDLIDFDKLKKSNAHYNLQNAFNLAEQHLGLTKLLDPED-IS 244
           ++ W +G+AF ALIH   PD  D+ +L+  N  YN + AF+ AE+   ++ LLD ED I 
Sbjct: 38  SSCWNNGLAFCALIHHFYPDAFDYSQLQPQNRRYNFELAFDTAEKLADISPLLDVEDMIK 217

Query: 245 VDHPDEKSIITYVVTYY 261
           + +PD K + TYV ++Y
Sbjct: 218 MKNPDWKCVFTYVQSFY 268
>09711
          Length = 3041

 Score = 64.7 bits (156), Expect = 4e-10,   Method: Compositional matrix adjust.
 Identities = 65/253 (25%), Positives = 122/253 (48%), Gaps = 22/253 (8%)
 Frame = +1

Query: 13  LSPAYTGQVPYNYNQLEGRFKQLQD--EREAVQKKTFTKWVNSHLARVSCRITDLYTDLR 70
           L+ A+   +  NY  L+    +++D  + E+ ++KT+  W+NS    VS  +  LY+DL 
Sbjct: 754 LNLAFVANLFNNYPALDTPQVEVEDVMKEESREEKTYRNWMNS--LGVSPFVHHLYSDLY 927

Query: 71  DGRMLIKLLEVLSGERL------PKPTKGRMRIHCLENVDKALQF---LKEQRVHLENMG 121
           DG ++ +L + +    +       K  K + R   +EN + A++    +K  +V L  + 
Sbjct: 928 DGLIIFQLYDYIQPGLVDWSKVKKKFNKLKARFERIENCNYAVELGPQVKLVKVKLVGIA 1107

Query: 122 SHDIVDGNHRLTLGLIWTIILRFQIQDISVETEDNKEKKSAKDALLLWCQMK------TA 175
             DI+DGN  LTLGL+W ++  + +  +S  TE+N  K  + + ++ W   K       +
Sbjct: 1108GQDILDGNPVLTLGLVWQLMRAYTLAILSKITENN--KPISDNEIITWVNSKIKKDDRIS 1281

Query: 176 GYPNVNIHNFTTSWRDGMAFNALIHKHRPDLIDFDKLKKSNAHY-----NLQNAFNLAEQ 230
           G+ +  ++       DG+    +I   +P ++++D +  S   Y     N + A  LA +
Sbjct: 1282GFQDRKLN-------DGVIVARVIEAIKPGIVNWDNIDCSARDYQDRLTNARYAIGLARK 1440

Query: 231 HLGLTKLLDPEDI 243
            +G      PEDI
Sbjct: 1441-IGAGVYALPEDI 1476

 Score = 43.5 bits (101), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 47/192 (24%), Positives = 80/192 (41%), Gaps = 27/192 (14%)
 Frame = +1

Query: 40  EAVQKKTFTKWVNSHLARVS-CR--------ITDLYTDLRDGRMLIKLLEVLSGERLPKP 90
           +A ++K F +W+N HL+    C+         T L+  + DG +L KL+       + + 
Sbjct: 43  KAGEQKAFAEWINRHLSDXPDCKHLLPLDADGTQLFGQMADGVLLCKLINHSVSNTIDER 222

Query: 91  TKGRMRIHCL---ENVDKALQFLKEQRVHLENMGSHDIVDGNHRLTLGLIWTIILRFQIQ 147
           T  +  +      EN+  A+           N+G  D+  G   L LGL+W II    + 
Sbjct: 223 TINKQNLSLYRRHENLTLAVNSAGAIGCTTVNIGPEDLAAGRPHLVLGLLWQIIRIGLLS 402

Query: 148 DISV-------------ETEDNKEKKSAKDALLLWC--QMKTAGYPNVNIHNFTTSWRDG 192
           DI++             ET ++  + S +  LL W    +  AG  +  I NF    +D 
Sbjct: 403 DINLAHHPGLVNLLLDGETIEDLIRLSPEQILLRWVNYHLNRAGC-DRQIXNFGEDIKDS 579

Query: 193 MAFNALIHKHRP 204
            A+  L+ +  P
Sbjct: 580 EAYTHLLKQISP 615
>38533
          Length = 380

 Score = 63.9 bits (154), Expect = 7e-10,   Method: Compositional matrix adjust.
 Identities = 47/127 (37%), Positives = 70/127 (55%), Gaps = 9/127 (7%)
 Frame = +1

Query: 1481 VEDEILWVG-ERMPLATSTDHGHNLQTVQLLIKKNQTLQKEIQGHQPRIDDIFERSQNII 1539
            VEDE+ W   +R P+A STD G++L  VQ L+KK+Q L+ EI  H+P ID +   +Q +I
Sbjct: 1    VEDELSWYY*DRKPIAESTDLGNSLTAVQNLMKKHQALESEIVAHEPLIDAVATSAQQMI 180

Query: 1540 TDSSSLNAEAIRQRLADL------KQLWGLLIEETEKRHRRLEEA--HKAQQYYFDAAEA 1591
                   A+ I+ RL DL       Q++ LL         ++E A    AQ++Y +  E 
Sbjct: 181  RTKHFATAD-IQTRLDDLTSPAQRSQVFYLL--------*KVETAGCFGAQKFYMEVNEV 333

Query: 1592 EAWMSEQ 1598
            E WM+E+
Sbjct: 334  ELWMNEK 354

 Score = 44.7 bits (104), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 30/116 (25%), Positives = 53/116 (45%), Gaps = 1/116 (0%)
 Frame = +1

Query: 741 DDIDAWMLDILKIVSSNDVGHDEYSTQSLVKKHKDVAEEITNYRPTIDTLHEQASALPQA 800
           D++  +  D   I  S D+G+   + Q+L+KKH+ +  EI  + P ID +   A  + + 
Sbjct: 7   DELSWYY*DRKPIAESTDLGNSLTAVQNLMKKHQALESEIVAHEPLIDAVATSAQQMIRT 186

Query: 801 -HAESPDVKGRLAGIEERCKEMAELTRLRKQALQDTLALYKMFSEADACELWIDEK 855
            H  + D++ RL  +    +       L K          K + E +  ELW++EK
Sbjct: 187 KHFATADIQTRLDDLTSPAQRSQVFYLL*KVETAGCFGAQKFYMEVNEVELWMNEK 354

 Score = 37.4 bits (85), Expect = 0.065,   Method: Compositional matrix adjust.
 Identities = 17/57 (29%), Positives = 28/57 (49%)
 Frame = +1

Query: 643 EKEKILSSDDYGKDLTSVMRLLSKHRAFEDEMSGRSGHFEQAIKEGEDMIAEEHFGS 699
           +++ I  S D G  LT+V  L+ KH+A E E+       +      + MI  +HF +
Sbjct: 31  DRKPIAESTDLGNSLTAVQNLMKKHQALESEIVAHEPLIDAVATSAQQMIRTKHFAT 201

 Score = 34.7 bits (78), Expect = 0.44,   Method: Compositional matrix adjust.
 Identities = 25/103 (24%), Positives = 51/103 (49%), Gaps = 2/103 (1%)
 Frame = +1

Query: 1182 TEMPTTLEGAEAAIKKQEDFMTTMDANEEKINAVVETGRRLVSDGNINSDRIQEKVDSID 1241
            T++  +L   +  +KK +   + + A+E  I+AV  + ++++   +  +  IQ ++D  D
Sbjct: 55   TDLGNSLTAVQNLMKKHQALESEIVAHEPLIDAVATSAQQMIRTKHFATADIQTRLD--D 228

Query: 1242 DRHRKNREAASELLMRLKDNRDL--QKFLQDCQELSLWINEKM 1282
                  R     LL +++       QKF  +  E+ LW+NEK+
Sbjct: 229  LTSPAQRSQVFYLL*KVETAGCFGAQKFYMEVNEVELWMNEKI 357

 Score = 32.0 bits (71), Expect = 2.9,   Method: Compositional matrix adjust.
 Identities = 17/62 (27%), Positives = 34/62 (54%)
 Frame = +1

Query: 1922 EAQEKPRDVSSVELLMNNHQGIKAEIDARNDSFTACIELGKSLLARKHYASEEIKEKLLQ 1981
            E+ +    +++V+ LM  HQ +++EI A      A     + ++  KH+A+ +I+ +L  
Sbjct: 49   ESTDLGNSLTAVQNLMKKHQALESEIVAHEPLIDAVATSAQQMIRTKHFATADIQTRLDD 228

Query: 1982 LT 1983
            LT
Sbjct: 229  LT 234

 Score = 30.8 bits (68), Expect = 6.3,   Method: Compositional matrix adjust.
 Identities = 17/54 (31%), Positives = 27/54 (50%)
 Frame = +1

Query: 956  SWIREKTKVIESTQDLGNDLAGVMALQRKLTGMERDLVAIEAKLSDLQKEAEKL 1009
            SW     K I  + DLGN L  V  L +K   +E ++VA E  +  +   A+++
Sbjct: 16   SWYY*DRKPIAESTDLGNSLTAVQNLMKKHQALESEIVAHEPLIDAVATSAQQM 177
>22703
          Length = 906

 Score = 60.5 bits (145), Expect = 8e-09,   Method: Compositional matrix adjust.
 Identities = 33/111 (29%), Positives = 63/111 (56%)
 Frame = -3

Query: 1952 DSFTACIELGKSLLARKHYASEEIKEKLLQLTEKRKEMIDKWEDRWEWLRLILEVHQFSR 2011
            + F    + G+S +A  H+ S+EI+EK+ QL +  + +I   E R +  +  LE  Q   
Sbjct: 886  EPFDKFRKTGRSFIANGHFLSKEIEEKIKQLDQSLEGLIRNLEHRRKLHQQNLEAQQLRH 707

Query: 2012 DASVAEAWLLGQEPYLSSREIGQSVDEVEKLIKRHEAFEKSAATWDERFSA 2062
            +    EAW+  +EP L  ++ G+S++  E++++RH+ F K+    ++R +A
Sbjct: 706  EMEQIEAWMNLREPLLKEKKFGESIEGAEEMLRRHD*F*KTVTAQEDRVNA 554

 Score = 43.5 bits (101), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 25/89 (28%), Positives = 52/89 (58%)
 Frame = -3

Query: 1127 LRQRLQALDTGWNELHKMWENRQNLLSQSHAYQQFLRDTKQAEAFLNNQEYVLAHTEMPT 1186
            + ++++ LD     L +  E+R+ L  Q+   QQ   + +Q EA++N +E +L   +   
Sbjct: 817  IEEKIKQLDQSLEGLIRNLEHRRKLHQQNLEAQQLRHEMEQIEAWMNLREPLLKEKKFGE 638

Query: 1187 TLEGAEAAIKKQEDFMTTMDANEEKINAV 1215
            ++EGAE  +++ + F  T+ A E+++NA+
Sbjct: 637  SIEGAEEMLRRHD*F*KTVTAQEDRVNAL 551
>32371
          Length = 625

 Score = 41.2 bits (95), Expect(3) = 2e-08,   Method: Compositional matrix adjust.
 Identities = 21/48 (43%), Positives = 29/48 (60%), Gaps = 1/48 (2%)
 Frame = -2

Query: 204 PDLIDFDKLKKSNAHYNLQNAFNLAEQHLGLTKLLDPED-ISVDHPDE 250
           PDLID+D L K N  YN   AF +AEQ L +   L+  D +++  PD+
Sbjct: 549 PDLIDYDSLSKENVLYNNNLAFTVAEQELDIPAFLEAADMVALRTPDK 406

 Score = 33.5 bits (75), Expect(3) = 2e-08,   Method: Composition-based stats.
 Identities = 12/25 (48%), Positives = 19/25 (76%)
 Frame = -1

Query: 179 NVNIHNFTTSWRDGMAFNALIHKHR 203
           +V+I +   SWR+G+AF A+IH+ R
Sbjct: 625 SVDIKDLLVSWRNGLAFCAIIHRFR 551

 Score = 23.1 bits (48), Expect(3) = 2e-08,   Method: Composition-based stats.
 Identities = 10/23 (43%), Positives = 13/23 (56%)
 Frame = -3

Query: 252 SIITYVVTYYHYFSKMKALAVEG 274
           S+ITYV  YY+  S +  L   G
Sbjct: 401 SVITYVSQYYNKLSTLPQLGGPG 333
>09100
          Length = 930

 Score = 54.3 bits (129), Expect = 5e-07,   Method: Compositional matrix adjust.
 Identities = 32/110 (29%), Positives = 57/110 (51%), Gaps = 7/110 (6%)
 Frame = +1

Query: 43  QKKTFTKWVNSHLARVSCR--ITDLYTDLRDGRMLIKLLEVLSGERLPK----PTK-GRM 95
           Q   +  W+NS L +      I DL  D+RDG +   ++ ++S +++P     PT    M
Sbjct: 463 QLSAYMAWINSQLKKKPGAHLIEDLRHDMRDGVVFADVIHIVSKQQIPGIQNVPTTLDEM 642

Query: 96  RIHCLENVDKALQFLKEQRVHLENMGSHDIVDGNHRLTLGLIWTIILRFQ 145
           R    +NVD+ L F+ + R+ +  + S DIV+GN +  + LI  +   ++
Sbjct: 643 R----QNVDRVLHFMTQNRIKMHRISSRDIVEGNLKAVMRLILALAAHYK 780
>17567
          Length = 448

 Score = 50.1 bits (118), Expect = 9e-06,   Method: Compositional matrix adjust.
 Identities = 33/140 (23%), Positives = 62/140 (44%)
 Frame = -3

Query: 517 LQKIFQEMLYIMDWMDEMKVLLLSQDYGKHLLGVEDLLQKHALVEADIAIQAERVRGVNA 576
           L  +F+E+  I + + E++  ++ +DYGKHL   +D+L++H+L EA +     RVR +N 
Sbjct: 392 LMAMFREIESIQEELKEVQSKVVGEDYGKHLQATQDMLEQHSLQEAQLQALTRRVRKLNR 213

Query: 577 SAQKFATDGEGYKPCDPQVIRDRVAHMEFCYQELCQXXXXXXXXXXXXXXXWKFFWEMAE 636
            +Q              Q +  R+  +      +                 ++F  +  E
Sbjct: 212 KSQ----------GAQEQSLDKRLEALNAQLNNVQAQSDKRRQGLETAQQYYQFLQDTEE 63

Query: 637 EEGWIREKEKILSSDDYGKD 656
           E+ W+ E+   + S   GKD
Sbjct: 62  EDRWVGERIDAVRSPSLGKD 3

 Score = 43.9 bits (102), Expect = 8e-04,   Method: Compositional matrix adjust.
 Identities = 28/121 (23%), Positives = 60/121 (49%)
 Frame = -3

Query: 1383 LHGLESQIQSDDYGKDLTSVNILLKKQQMLENQMEVRKKEIEELQSQAQALSQEGKSTDE 1442
            L  ++S++  +DYGK L +   +L++  + E Q++   + + +L  ++Q     G     
Sbjct: 350  LKEVQSKVVGEDYGKHLQATQDMLEQHSLQEAQLQALTRRVRKLNRKSQ-----GAQEQS 186

Query: 1443 VDSKRLTVQTKFMELLEPLSERKHNLLASKEIHQFNRDVEDEILWVGERMPLATSTDHGH 1502
            +D +   +  +   +     +R+  L  +++ +QF +D E+E  WVGER+    S   G 
Sbjct: 185  LDKRLEALNAQLNNVQAQSDKRRQGLETAQQYYQFLQDTEEEDRWVGERIDAVRSPSLGK 6

Query: 1503 N 1503
            +
Sbjct: 5    D 3
>04951
          Length = 2852

 Score = 45.4 bits (106), Expect = 2e-04,   Method: Composition-based stats.
 Identities = 43/154 (27%), Positives = 76/154 (49%), Gaps = 10/154 (6%)
 Frame = +1

Query: 100 LENVDKALQF---LKEQRVHLENMGSHDIVDGNHRLTLGLIWTIILRFQIQDISVETEDN 156
           +EN + A+Q    +K  ++ L  +G  DI DGN  LTLGL+W ++  + +  +S  TED 
Sbjct: 7   IENCEYAVQLGPQMKVCKMKLVGIGGKDIHDGNPVLTLGLVWQLMRAYTLAILSKLTED- 183

Query: 157 KEKKSAKDALLL-WCQMKTAGYPNVNIHNFTTS-WRDGMAFNALIHKHRPDLIDFDKLKK 214
             KK  +D+ ++ W   K     +  I +F  S   DG+    +I   +P +++++ +  
Sbjct: 184 --KKPIQDSEIVDWVNSKVK--KDERIGSFQDSKLNDGVIVAKVIESIKPGIVNWENINP 351

Query: 215 SNAH-----YNLQNAFNLAEQHLGLTKLLDPEDI 243
           + +       N + A  LA + +G      PEDI
Sbjct: 352 NASEPDDRLANARYAIGLARK-IGAGVYALPEDI 450
>18202
          Length = 424

 Score = 43.9 bits (102), Expect = 8e-04,   Method: Composition-based stats.
 Identities = 33/133 (24%), Positives = 62/133 (46%), Gaps = 6/133 (4%)
 Frame = -1

Query: 45  KTFTKWVNSHLARVSCRITDLYTDLRDGRMLIKLLEVLSGERLPKPTKGRMRIHCLENVD 104
           + +  W NS L  V+  + ++ + +++GR+L +L++VL+      P  G +         
Sbjct: 385 QVYLSWANSVLCEVNSSVENV-SSIQEGRVLCELIDVLA------PEAGLLDKVQASGKS 227

Query: 105 KALQFLKEQRVHLENMG------SHDIVDGNHRLTLGLIWTIILRFQIQDISVETEDNKE 158
               F+     H++N G      + DI+DG+ +  L ++W +IL + I  I       + 
Sbjct: 226 GQRAFIYAALDHMKNHGIKIVFSTQDIMDGDIKSLLDVMWLLILNYGIHFIG-NNSFQRS 50

Query: 159 KKSAKDALLLWCQ 171
             + K  LL WCQ
Sbjct: 49  VGAGKKNLLDWCQ 11
>32088
          Length = 1928

 Score = 37.4 bits (85), Expect = 0.061,   Method: Composition-based stats.
 Identities = 37/152 (24%), Positives = 62/152 (40%), Gaps = 25/152 (16%)
 Frame = +1

Query: 43   QKKTFTKWVN---------SHLARVSCRITDLYTDLRDGRMLIKLLEVLSGERLPKPTKG 93
            ++K F  W+N          HL  V+    DL+  + DG +L KL+       + +    
Sbjct: 1264 EQKAFAAWINRHLKDDPDCKHLMEVNEEGDDLFKKVGDGILLCKLINHSVSNTIDERAIN 1443

Query: 94   RMRI---HCLENVDKALQFLKEQRVHLENMGSHDIVDGNHRLTLGLIWTIILRFQIQDIS 150
            +  +   H  EN+  A+           N+G  D+  G   L LGL+W II    + DI+
Sbjct: 1444 KSNLNVYHRHENLTLAVNSAGSIGCTTVNIGPEDLAAGRPHLVLGLLWQIIRIGLLSDIN 1623

Query: 151  V-------------ETEDNKEKKSAKDALLLW 169
            +             ET ++  + S ++ LL W
Sbjct: 1624 LAHHPGLVNLLREGETIEDFMRLSPEEILLRW 1719
>18556
          Length = 799

 Score = 35.4 bits (80), Expect = 0.25,   Method: Compositional matrix adjust.
 Identities = 21/75 (28%), Positives = 38/75 (50%), Gaps = 1/75 (1%)
 Frame = +2

Query: 165 ALLLWCQMKTAGYP-NVNIHNFTTSWRDGMAFNALIHKHRPDLIDFDKLKKSNAHYNLQN 223
           +LL W  ++ A Y     +   +  +R+G    ALI + RPDLID+   K  +     + 
Sbjct: 44  SLLRWISVQLAAYQFTAELKEPSDVFRNGRVLCALISRFRPDLIDYAATKDMSPLECNEL 223

Query: 224 AFNLAEQHLGLTKLL 238
           AF + E+ L + +++
Sbjct: 224 AFAVLERELHIDRIM 268
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|19527028|ref|NP_598569.1| high density lipoprotein
binding protein [Mus musculus]
         (1268 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

05665                                                                 463   e-130
13185                                                                 309   4e-84
31560                                                                 146   3e-56
13631                                                                  85   2e-16
09451                                                                  40   0.005
03467                                                                  39   0.015
09541                                                                  37   0.036
30669                                                                  36   0.11 
26269                                                                  33   0.84 
04763                                                                  33   0.91 
18876                                                                  32   2.0  
>05665
          Length = 1610

 Score =  463 bits (1191), Expect = e-130,   Method: Compositional matrix adjust.
 Identities = 233/428 (54%), Positives = 311/428 (72%), Gaps = 3/428 (0%)
 Frame = -3

Query: 37   PPTYKDAFPPLPEKAACLESAQEPAGAWSNKIRPIKASVITQVFHVPLEERKYKDMNQ-- 94
            PPTY  AFP L  +   L  A   + AW  K +  + S  TQVF VP+ ER++K++N+  
Sbjct: 1407 PPTYDAAFPALTTEPRPLNPALS-SSAWQPKFQA-RVSKCTQVFTVPMVERRFKEVNEHR 1234

Query: 95   FG-EGEQAKICLEIMQRTGAHLELSLAKDQGLSIMVSGKLDAVMKARKDIVARLQTQASA 153
            FG E +QAKIC +IM + G  +E+SLA+DQ ++++++G+ D+VMKAR+++V +LQTQA  
Sbjct: 1233 FGDESDQAKICKDIMAKYGVAIEISLARDQSMTVVINGRSDSVMKARREVVGKLQTQAVY 1054

Query: 154  TVPIPKEHHRFVIGKNGEKLQDLELKTATKIQIPRPDDPSNQIKITGTKEGIEKARHEVL 213
             V IP+EHHRFV+GK+G+KLQ+LEL T+TKI IPR D+ S+ IKI+GTKEGIEKARHE+ 
Sbjct: 1053 QVKIPREHHRFVLGKSGKKLQELELATSTKITIPRTDENSDVIKISGTKEGIEKARHELE 874

Query: 214  LISAEQDKRAVERLEVEKAFHPFIAGPYNRLVGEIMQETGTRINIPPPSVNRTEIVFTGE 273
             IS EQ KRA ERL V+KAFHPFI GP+N+ V + ++ETG  IN+PP SVN+ EIV +GE
Sbjct: 873  CISEEQSKRAFERLPVQKAFHPFICGPFNQNVKQWIEETGASINVPPASVNKDEIVVSGE 694

Query: 274  KEQLAQAVARXXXXXXXXXXXXXXXXXXXXXSQHKYVIGPKGNSLQEILERTGVSVEIPP 333
            KE +A+ +                       +QH+YVIGP+GN +QEIL+   V++++PP
Sbjct: 693  KEGVAKCIQNIMRIYEEKKRKCQNGSLWK*ETQHRYVIGPRGNGIQEILQHCDVALDVPP 514

Query: 334  SDSISETVILRGEPEKLGQALTEVYAKANSFTVSSVSAPSWLHRFIIGKKGQNLAKITQQ 393
             DS SET+ LRGE +KLG ALT VY+KANS + S V APSWLHRFIIGKKG N+ +IT++
Sbjct: 513  LDSPSETITLRGEQDKLGPALTMVYSKANSVSTSEVMAPSWLHRFIIGKKGANIRRITEE 334

Query: 394  MPKVHIEFTEGEDKITLEGPTEDVNVAQEQIEGMVKDLINRMDYVEINIDHKFHRHLIGK 453
             PKVHIEFTEG+DKIT+EG  E+V  A   +E +V DL NRMDY EI +D KFH+H+IGK
Sbjct: 333  HPKVHIEFTEGQDKITVEGSPEEVQEAILALEVIVTDLKNRMDYAEIEVDPKFHKHIIGK 154

Query: 454  SGANINRI 461
            +GAN  ++
Sbjct: 153  NGANSKKL 130

 Score =  110 bits (275), Expect = 4e-24,   Method: Compositional matrix adjust.
 Identities = 95/387 (24%), Positives = 176/387 (45%), Gaps = 12/387 (3%)
 Frame = -3

Query: 162  HRFVIGKNGEKL-QDLELKTATKIQIPRPDDPSNQIKITGTKEGIEKARHEVLLISAEQD 220
            HRF    +  K+ +D+  K    I+I    D S  + I G  + + KAR EV+    +  
Sbjct: 1239 HRFGDESDQAKICKDIMAKYGVAIEISLARDQSMTVVINGRSDSVMKARREVV---GKLQ 1069

Query: 221  KRAVERLEVEKAFHPFIAGPYNRLVGEIMQETGTRINIPPPSVNRTEIVFTGEKEQLAQA 280
             +AV ++++ +  H F+ G   + + E+   T T+I IP    N   I  +G KE + +A
Sbjct: 1068 TQAVYQVKIPREHHRFVLGKSGKKLQELELATSTKITIPRTDENSDVIKISGTKEGIEKA 889

Query: 281  VARXXXXXXXXXXXXXXXXXXXXXSQHKYVIGPKGNSLQEILERTGVSVEIPPSDSISET 340
                                    + H ++ GP   ++++ +E TG S+ +PP+    + 
Sbjct: 888  -RHELECISEEQSKRAFERLPVQKAFHPFICGPFNQNVKQWIEETGASINVPPASVNKDE 712

Query: 341  VILRGEPEKLGQALTEVYAKANSFTVSSVSAPSW----LHRFIIGKKGQNLAKITQQMPK 396
            +++ GE E + + +  +            +   W     HR++IG +G  + +I Q    
Sbjct: 711  IVVSGEKEGVAKCIQNIMRIYEEKKRKCQNGSLWK*ETQHRYVIGPRGNGIQEILQ---- 544

Query: 397  VHIEFTEGEDKITLEGPTEDVNVAQEQIE-----GMVKDLINRMDYVEINIDHKFHRHLI 451
             H +     D   L+ P+E + +  EQ +      MV    N +   E+      HR +I
Sbjct: 543  -HCDV--ALDVPPLDSPSETITLRGEQDKLGPALTMVYSKANSVSTSEVMAPSWLHRFII 373

Query: 452  GKSGANINRIKDQY-KVSVRIPPDSEKSNLIRIEGDPQGVQQAKRELLELASRMENER-T 509
            GK GANI RI +++ KV +     +E  + I +EG P+ VQ+A   L  + + ++N    
Sbjct: 372  GKKGANIRRITEEHPKVHIEF---TEGQDKITVEGSPEEVQEAILALEVIVTDLKNRMDY 202

Query: 510  KDLIIEQRFHRTIIGQKGERIREIRDK 536
             ++ ++ +FH+ IIG+ G   +++  K
Sbjct: 201  AEIEVDPKFHKHIIGKNGANSKKLFSK 121

 Score = 94.7 bits (234), Expect = 2e-19,   Method: Compositional matrix adjust.
 Identities = 84/370 (22%), Positives = 164/370 (44%), Gaps = 3/370 (0%)
 Frame = -3

Query: 376  HRFIIGKKGQNLAKITQQMPKVHIEFTEGEDK---ITLEGPTEDVNVAQEQIEGMVKDLI 432
            HRF        + K       V IE +   D+   + + G ++ V  A+ ++ G ++   
Sbjct: 1239 HRFGDESDQAKICKDIMAKYGVAIEISLARDQSMTVVINGRSDSVMKARREVVGKLQT-- 1066

Query: 433  NRMDYVEINIDHKFHRHLIGKSGANINRIKDQYKVSVRIPPDSEKSNLIRIEGDPQGVQQ 492
                  ++ I  + HR ++GKSG  +  ++      + IP   E S++I+I G  +G+++
Sbjct: 1065 --QAVYQVKIPREHHRFVLGKSGKKLQELELATSTKITIPRTDENSDVIKISGTKEGIEK 892

Query: 493  AKRELLELASRMENERTKDLIIEQRFHRTIIGQKGERIREIRDKFPEVIINFPDPAQKSD 552
            A+ EL  ++        + L +++ FH  I G   + +++  ++     IN P  +   D
Sbjct: 891  ARHELECISEEQSKRAFERLPVQKAFHPFICGPFNQNVKQWIEE-TGASINVPPASVNKD 715

Query: 553  IVQLRGPKNEVEKCTKYMQKMVADLVENSYSISVPIFKQFHXXXXXXXXXXXXXXREESN 612
             + + G K  V KC + + ++  +      + S+   +  H               +  +
Sbjct: 714  EIVVSGEKEGVAKCIQNIMRIYEEKKRKCQNGSLWK*ETQHRYVIGPRGNGIQEILQHCD 535

Query: 613  TKIDLPAENSNSETIIITGKRANCEAARSRILSIQKDLANIAEVEVSIPAKLHNSLIGTK 672
              +D+P  +S SETI + G++     A + + S      +++  EV  P+ LH  +IG K
Sbjct: 534  VALDVPPLDSPSETITLRGEQDKLGPALTMVYS---KANSVSTSEVMAPSWLHRFIIGKK 364

Query: 673  GRLIRSIMEECGGVHIHFPVEGSGSDTVVIRGPSSDVEKAKKQLLHLAEEKQTKSFTVDI 732
            G  IR I EE   VHI F     G D + + G   +V++A   L  +  + + +    +I
Sbjct: 363  GANIRRITEEHPKVHIEF---TEGQDKITVEGSPEEVQEAILALEVIVTDLKNRMDYAEI 193

Query: 733  RAKPEYHKFL 742
               P++HK +
Sbjct: 192  EVDPKFHKHI 163

 Score = 90.1 bits (222), Expect = 6e-18,   Method: Compositional matrix adjust.
 Identities = 100/403 (24%), Positives = 179/403 (44%), Gaps = 1/403 (0%)
 Frame = -3

Query: 672  KGRLIRSIMEECGGVHIHFPVEGSGSDTVVIRGPSSDVEKAKKQLLHLAEEKQTKSFTVD 731
            + ++ + IM + G V I   +    S TVVI G S  V KA+++++    + QT++    
Sbjct: 1215 QAKICKDIMAKYG-VAIEISLARDQSMTVVINGRSDSVMKARREVV---GKLQTQA-VYQ 1051

Query: 732  IRAKPEYHKFLXXXXXXXXRKVRDSTGARIIFPAAEDKDQDLITIIGKEDAVREAQKELE 791
            ++   E+H+F+        +++  +T  +I  P   D++ D+I I G ++ + +A+ ELE
Sbjct: 1050 VKIPREHHRFVLGKSGKKLQELELATSTKITIPRT-DENSDVIKISGTKEGIEKARHELE 874

Query: 792  ALIQNLENVVEDYMLVDPKHHRHFVIRRGQVLREIAEEYGGVMVSFPRSGTQSDKVTLKG 851
             + +       + + V    H        Q +++  EE G   ++ P +    D++ + G
Sbjct: 873  CISEEQSKRAFERLPVQKAFHPFICGPFNQNVKQWIEETGA-SINVPPASVNKDEIVVSG 697

Query: 852  AKDCVEAAKKRIQEIIEDLEAQVTVECAIP-QKFHRSVMGPKGSRIQQITRDYNVQIKFP 910
             K+ V    + I  I E+ + +         +  HR V+GP+G+ IQ+I +  +V +  P
Sbjct: 696  EKEGVAKCIQNIMRIYEEKKRKCQNGSLWK*ETQHRYVIGPRGNGIQEILQHCDVALDVP 517

Query: 911  DREENPVHSVEPSIQENGDEAGEGREAKETDPGSPRRCDIIIISGRXXXXXXXXXXXXXX 970
                 P+ S   +I   G          E D   P    + ++  +              
Sbjct: 516  -----PLDSPSETITLRG----------EQDKLGPA---LTMVYSKANSVS--------- 418

Query: 971  VPVTIEVEVPFDLHRYIIGQKGSGIRKMMDEFEVNIHVPAPELQSDTIAITGLAANLDRA 1030
               T EV  P  LHR+IIG+KG+ IR++ +E    +H+   E Q D I + G    +  A
Sbjct: 417  ---TSEVMAPSWLHRFIIGKKGANIRRITEEHP-KVHIEFTEGQ-DKITVEGSPEEVQEA 253

Query: 1031 KAGLLDRVKELQAEQEDRALRSFKLSVTVDPKYHPKIIGRKGA 1073
               L   V +L+        R     + VDPK+H  IIG+ GA
Sbjct: 252  ILALEVIVTDLKN-------RMDYAEIEVDPKFHKHIIGKNGA 145

 Score = 79.3 bits (194), Expect = 9e-15,   Method: Compositional matrix adjust.
 Identities = 87/389 (22%), Positives = 169/389 (43%), Gaps = 2/389 (0%)
 Frame = -3

Query: 615  IDLPAENSNSETIIITGKRANCEAARSRILSIQKDLANIAEVEVSIPAKLHNSLIGTKGR 674
            I++      S T++I G+  +   AR  ++     L   A  +V IP + H  ++G  G+
Sbjct: 1170 IEISLARDQSMTVVINGRSDSVMKARREVVG---KLQTQAVYQVKIPREHHRFVLGKSGK 1000

Query: 675  LIRSIMEECGGVHIHFPVEGSGSDTVVIRGPSSDVEKAKKQLLHLAEEKQTKSFTVDIRA 734
             ++  +E      I  P     SD + I G    +EKA+ +L  ++EE+  ++F   +  
Sbjct: 999  KLQE-LELATSTKITIPRTDENSDVIKISGTKEGIEKARHELECISEEQSKRAFE-RLPV 826

Query: 735  KPEYHKFLXXXXXXXXRKVRDSTGARIIFPAAEDKDQDLITIIGKEDAVREAQKELEALI 794
            +  +H F+        ++  + TGA I  P A   ++D I + G+++ V +  + +  + 
Sbjct: 825  QKAFHPFICGPFNQNVKQWIEETGASINVPPA-SVNKDEIVVSGEKEGVAKCIQNIMRIY 649

Query: 795  QNLENVVEDYMLVD-PKHHRHFVIRRGQVLREIAEEYGGVMVSFPRSGTQSDKVTLKGAK 853
            +  +   ++  L      HR+ +  RG  ++EI + +  V +  P   + S+ +TL+G +
Sbjct: 648  EEKKRKCQNGSLWK*ETQHRYVIGPRGNGIQEILQ-HCDVALDVPPLDSPSETITLRGEQ 472

Query: 854  DCVEAAKKRIQEIIEDLEAQVTVECAIPQKFHRSVMGPKGSRIQQITRDY-NVQIKFPDR 912
            D +  A   +  +     +  T E   P   HR ++G KG+ I++IT ++  V I+F   
Sbjct: 471  DKLGPA---LTMVYSKANSVSTSEVMAPSWLHRFIIGKKGANIRRITEEHPKVHIEF--- 310

Query: 913  EENPVHSVEPSIQENGDEAGEGREAKETDPGSPRRCDIIIISGRXXXXXXXXXXXXXXVP 972
                                EG++ K T  GSP      I++                  
Sbjct: 309  -------------------TEGQD-KITVEGSPEEVQEAILALEVIVTDLKNRMDYA--- 199

Query: 973  VTIEVEVPFDLHRYIIGQKGSGIRKMMDE 1001
               E+EV    H++IIG+ G+  +K+  +
Sbjct: 198  ---EIEVDPKFHKHIIGKNGANSKKLFSK 121

 Score = 76.6 bits (187), Expect = 6e-14,   Method: Compositional matrix adjust.
 Identities = 69/297 (23%), Positives = 128/297 (43%), Gaps = 9/297 (3%)
 Frame = -3

Query: 306  QHKYVIGPKGNSLQEILERTGVSVEIPPSDSISETVILRGEPEKLGQA---LTEVYAKAN 362
             H++V+G  G  LQE+   T   + IP +D  S+ + + G  E + +A   L  +  + +
Sbjct: 1032 HHRFVLGKSGKKLQELELATSTKITIPRTDENSDVIKISGTKEGIEKARHELECISEEQS 853

Query: 363  SFTVSSVSAPSWLHRFIIGKKGQNLAKITQQ------MPKVHIEFTEGEDKITLEGPTED 416
                  +      H FI G   QN+ +  ++      +P   +     +D+I + G  E 
Sbjct: 852  KRAFERLPVQKAFHPFICGPFNQNVKQWIEETGASINVPPASV----NKDEIVVSGEKEG 685

Query: 417  VNVAQEQIEGMVKDLINRMDYVEINIDHKFHRHLIGKSGANINRIKDQYKVSVRIPPDSE 476
            V    + I  + ++   +     +      HR++IG  G  I  I     V++ +PP   
Sbjct: 684  VAKCIQNIMRIYEEKKRKCQNGSLWK*ETQHRYVIGPRGNGIQEILQHCDVALDVPPLDS 505

Query: 477  KSNLIRIEGDPQGVQQAKRELLELASRMENERTKDLIIEQRFHRTIIGQKGERIREIRDK 536
             S  I + G+   +  A   L  + S+  +  T +++     HR IIG+KG  IR I ++
Sbjct: 504  PSETITLRGEQDKLGPA---LTMVYSKANSVSTSEVMAPSWLHRFIIGKKGANIRRITEE 334

Query: 537  FPEVIINFPDPAQKSDIVQLRGPKNEVEKCTKYMQKMVADLVENSYSISVPIFKQFH 593
             P+V I F    +  D + + G   EV++    ++ +V DL        + +  +FH
Sbjct: 333  HPKVHIEF---TEGQDKITVEGSPEEVQEAILALEVIVTDLKNRMDYAEIEVDPKFH 172

 Score = 63.2 bits (152), Expect = 6e-10,   Method: Compositional matrix adjust.
 Identities = 52/174 (29%), Positives = 88/174 (50%), Gaps = 3/174 (1%)
 Frame = -3

Query: 984  HRYIIGQKGSGIRKMMDEFEVNIHVPAPELQSDTIAITGLAANLDRAKAGLLDRVKELQA 1043
            HRY+IG +G+GI++++   +V + VP  +  S+TI + G    L  A   +  +      
Sbjct: 594  HRYVIGPRGNGIQEILQHCDVALDVPPLDSPSETITLRGEQDKLGPALTMVYSKA----- 430

Query: 1044 EQEDRALRSFKLSVTVDPKY-HPKIIGRKGAVITQIRLEH-EVNIQFPDKDDGNQPQDQI 1101
                    S   S  + P + H  IIG+KGA I +I  EH +V+I+F       + QD+I
Sbjct: 429  -------NSVSTSEVMAPSWLHRFIIGKKGANIRRITEEHPKVHIEF------TEGQDKI 289

Query: 1102 TITGYEKNTEAARDAILKIVGELE-QMVSEDVPLDHRVHARIIGARGKAIRKIM 1154
            T+ G  +  + A  A+  IV +L+ +M   ++ +D + H  IIG  G   +K+ 
Sbjct: 288  TVEGSPEEVQEAILALEVIVTDLKNRMDYAEIEVDPKFHKHIIGKNGANSKKLF 127
>13185
          Length = 1678

 Score =  309 bits (792), Expect = 4e-84,   Method: Compositional matrix adjust.
 Identities = 155/292 (53%), Positives = 210/292 (71%), Gaps = 6/292 (2%)
 Frame = +3

Query: 983  LHRYIIGQKGSGIRKMMDEFEVNIHVPAPELQSDTIAITGLAANLDRAKAGLLDRVKELQ 1042
            LH +    +G  +R+MM +F+VNI +P P   SD + +TG   N++RA+  L +RV +L 
Sbjct: 465  LHHW---PEGRDVRRMMQDFDVNISIPPPSDNSDLVRVTGPPENVERARKALEERVGQLD 635

Query: 1043 AEQEDRALRSFKLSVTVDPKYHPKIIGRKGAVITQIRLEHEVNIQFPDKDDGNQPQDQIT 1102
            AE+EDRAL+ F+L V VDP++HPKIIGRKGAVI++IR +H+VN+QFPD+++ NQ    IT
Sbjct: 636  AEREDRALKGFQLQVEVDPRHHPKIIGRKGAVISKIRADHDVNVQFPDRNEENQ--GLIT 809

Query: 1103 ITGYEKNTEAARDAILKIVGELEQMVSEDVPLDHRVHARIIGARGKAIRKIMDEFKVDIR 1162
            ITGYE+N + AR+ IL IV +LE MV+E+V +DHRVH RIIG +G+ +R+IMD+F VDIR
Sbjct: 810  ITGYEQNAQRAREEILGIVKDLEDMVTEEVQIDHRVHPRIIGGKGRTVRRIMDDFNVDIR 989

Query: 1163 FPQSGAPDPNCVTVTGLPENVEEAIDHILNLEEEYLADVVDSEALQVYMKPPAHEESRAP 1222
            FP+S + DPN VT+TG  + V +  DH+LNL+EEYL DVVD E LQ   +PP+     AP
Sbjct: 990  FPRSDSGDPNMVTITGPEDAVYDCKDHLLNLQEEYLQDVVDQEYLQDLQRPPSKTNDDAP 1169

Query: 1223 SK-----GFVVRDAPWTSNSSEKAPDMSSSEEFPSFGAQVAPKT-LPWGPKR 1268
             +     GFVVR+APW +     APD +S+EEFPSFG+ V PK+   WGP R
Sbjct: 1170 PRRGEPQGFVVRNAPWHA----AAPDTASTEEFPSFGSVVKPKSGHAWGPMR 1313

 Score =  157 bits (397), Expect = 2e-38,   Method: Compositional matrix adjust.
 Identities = 85/171 (49%), Positives = 112/171 (65%), Gaps = 5/171 (2%)
 Frame = +1

Query: 828 EEYGGVMVSFPRSGTQSDKVTLKGAKDCVEAAKKRIQEIIEDLEAQVTVECAIPQKFHRS 887
           EEYGGV VSFPRSG +S++V +KG+KDCVE AKK+I +I+ DL+AQVTVEC I Q++HR+
Sbjct: 1   EEYGGVTVSFPRSGVKSERVVIKGSKDCVEGAKKKITDIVADLDAQVTVECVISQQYHRT 180

Query: 888 VMGPKGSRIQQITRDYNVQIKFPDREENPVHSVEPSIQE-----NGDEAGEGREAKETDP 942
           VMG +GS +++ITR + V IKFPD+   P+ +      E     NGD + E    + T  
Sbjct: 181 VMGAQGSHVREITRTHEVGIKFPDK---PMPNGRQGEGEEEHVANGDVSSEEGSERGT-- 345

Query: 943 GSPRRCDIIIISGRXXXXXXXXXXXXXXVPVTIEVEVPFDLHRYIIGQKGS 993
              R+ DIIII+G+              VP+T EV VPFD HR+IIGQKG 
Sbjct: 346 ---RKSDIIIITGKPEKCEAAKKALLDLVPITEEVPVPFDYHRFIIGQKGG 489

 Score = 92.8 bits (229), Expect(2) = 2e-27,   Method: Compositional matrix adjust.
 Identities = 64/206 (31%), Positives = 98/206 (47%), Gaps = 9/206 (4%)
 Frame = +3

Query: 526 KGERIREIRDKFPEVIINFPDPAQKSDIVQLRGPKNEVEKCTKYMQKMVA-------DLV 578
           +G  +R +   F +V I+ P P+  SD+V++ GP   VE+  K +++ V        D  
Sbjct: 480 EGRDVRRMMQDF-DVNISIPPPSDNSDLVRVTGPPENVERARKALEERVGQLDAEREDRA 656

Query: 579 ENSYSISVPIFKQFHXXXXXXXXXXXXXXREESNTKIDLPAENSNSETII-ITGKRANCE 637
              + + V +  + H              R + +  +  P  N  ++ +I ITG   N +
Sbjct: 657 LKGFQLQVEVDPRHHPKIIGRKGAVISKIRADHDVNVQFPDRNEENQGLITITGYEQNAQ 836

Query: 638 AARSRILSIQKDLANIAEVEVSIPAKLHNSLIGTKGRLIRSIMEECGGVHIHFPVEGSGS 697
            AR  IL I KDL ++   EV I  ++H  +IG KGR +R IM++   V I FP   SG 
Sbjct: 837 RAREEILGIVKDLEDMVTEEVQIDHRVHPRIIGGKGRTVRRIMDDF-NVDIRFPRSDSGD 1013

Query: 698 -DTVVIRGPSSDVEKAKKQLLHLAEE 722
            + V I GP   V   K  LL+L EE
Sbjct: 1014PNMVTITGPEDAVYDCKDHLLNLQEE 1091

 Score = 49.3 bits (116), Expect(2) = 2e-27,   Method: Compositional matrix adjust.
 Identities = 38/151 (25%), Positives = 74/151 (49%), Gaps = 29/151 (19%)
 Frame = +1

Query: 406 DKITLEGPTEDVNVAQEQIEGMVKDLINRMDYVEINIDHKFHRHLIGKSGANINRIKDQY 465
           +++ ++G  + V  A+++I  +V DL  ++  VE  I  ++HR ++G  G+++  I   +
Sbjct: 52  ERVVIKGSKDCVEGAKKKITDIVADLDAQVT-VECVISQQYHRTVMGAQGSHVREITRTH 228

Query: 466 KVSVRIP----PD-------------------------SEKSNLIRIEGDPQGVQQAKRE 496
           +V ++ P    P+                         + KS++I I G P+  + AK+ 
Sbjct: 229 EVGIKFPDKPMPNGRQGEGEEEHVANGDVSSEEGSERGTRKSDIIIITGKPEKCEAAKKA 408

Query: 497 LLELASRMENERTKDLIIEQRFHRTIIGQKG 527
           LL+L        T+++ +   +HR IIGQKG
Sbjct: 409 LLDLVPI-----TEEVPVPFDYHRFIIGQKG 486

 Score = 84.3 bits (207), Expect(2) = 1e-24,   Method: Compositional matrix adjust.
 Identities = 56/207 (27%), Positives = 106/207 (51%), Gaps = 8/207 (3%)
 Frame = +3

Query: 672 KGRLIRSIMEECGGVHIHFPVEGSGSDTVVIRGPSSDVEKAKK-------QLLHLAEEKQ 724
           +GR +R +M++   V+I  P     SD V + GP  +VE+A+K       QL    E++ 
Sbjct: 480 EGRDVRRMMQDFD-VNISIPPPSDNSDLVRVTGPPENVERARKALEERVGQLDAEREDRA 656

Query: 725 TKSFTVDIRAKPEYHKFLXXXXXXXXRKVRDSTGARIIFPAAEDKDQDLITIIGKEDAVR 784
            K F + +   P +H  +         K+R      + FP   +++Q LITI G E   +
Sbjct: 657 LKGFQLQVEVDPRHHPKIIGRKGAVISKIRADHDVNVQFPDRNEENQGLITITGYEQNAQ 836

Query: 785 EAQKELEALIQNLENVVEDYMLVDPKHHRHFVIRRGQVLREIAEEYGGVMVSFPRSGT-Q 843
            A++E+  ++++LE++V + + +D + H   +  +G+ +R I +++  V + FPRS +  
Sbjct: 837 RAREEILGIVKDLEDMVTEEVQIDHRVHPRIIGGKGRTVRRIMDDF-NVDIRFPRSDSGD 1013

Query: 844 SDKVTLKGAKDCVEAAKKRIQEIIEDL 870
            + VT+ G +D V   K  +  + E+ 
Sbjct: 1014PNMVTITGPEDAVYDCKDHLLNLQEEY 1094

 Score = 48.5 bits (114), Expect(2) = 1e-24,   Method: Compositional matrix adjust.
 Identities = 46/168 (27%), Positives = 70/168 (41%), Gaps = 29/168 (17%)
 Frame = +1

Query: 535 DKFPEVIINFPDPAQKSDIVQLRGPKNEVEKCTKYMQKMVADLVENSYSISVPIFKQFHX 594
           +++  V ++FP    KS+ V ++G K+ VE   K +  +VADL +   ++   I +Q+H 
Sbjct: 1   EEYGGVTVSFPRSGVKSERVVIKGSKDCVEGAKKKITDIVADL-DAQVTVECVISQQYHR 177

Query: 595 XXXXXXXX-----------------------XXXXXREESNTKIDLPAENSN------SE 625
                                                EE     D+ +E  +      S+
Sbjct: 178 TVMGAQGSHVREITRTHEVGIKFPDKPMPNGRQGEGEEEHVANGDVSSEEGSERGTRKSD 357

Query: 626 TIIITGKRANCEAARSRILSIQKDLANIAEVEVSIPAKLHNSLIGTKG 673
            IIITGK   CEAA+  +L    DL  I E EV +P   H  +IG KG
Sbjct: 358 IIIITGKPEKCEAAKKALL----DLVPITE-EVPVPFDYHRFIIGQKG 486

 Score = 80.9 bits (198), Expect = 3e-15,   Method: Compositional matrix adjust.
 Identities = 63/204 (30%), Positives = 98/204 (48%), Gaps = 16/204 (7%)
 Frame = +3

Query: 313 PKGNSLQEILERTGVSVEIPPSDSISETVILRGEP-----------EKLGQALTEVYAKA 361
           P+G  ++ +++   V++ IPP    S+ V + G P           E++GQ   E   +A
Sbjct: 477 PEGRDVRRMMQDFDVNISIPPPSDNSDLVRVTGPPENVERARKALEERVGQLDAEREDRA 656

Query: 362 NSFTVSSVSAPSWLHRFIIGKKGQNLAKITQQMPKVHIEFT----EGEDKITLEGPTEDV 417
                  V      H  IIG+KG  ++KI      V+++F     E +  IT+ G  ++ 
Sbjct: 657 LKGFQLQVEVDPRHHPKIIGRKGAVISKIRADH-DVNVQFPDRNEENQGLITITGYEQNA 833

Query: 418 NVAQEQIEGMVKDLINRMDYVEINIDHKFHRHLIGKSGANINRIKDQYKVSVRIP-PDSE 476
             A+E+I G+VKDL + M   E+ IDH+ H  +IG  G  + RI D + V +R P  DS 
Sbjct: 834 QRAREEILGIVKDLED-MVTEEVQIDHRVHPRIIGGKGRTVRRIMDDFNVDIRFPRSDSG 1010

Query: 477 KSNLIRIEGDPQGVQQAKRELLEL 500
             N++ I G    V   K  LL L
Sbjct: 1011DPNMVTITGPEDAVYDCKDHLLNL 1082

 Score = 77.8 bits (190), Expect = 3e-14,   Method: Compositional matrix adjust.
 Identities = 53/169 (31%), Positives = 86/169 (50%), Gaps = 9/169 (5%)
 Frame = +3

Query: 751 RKVRDSTGARIIFPAAEDKDQDLITIIGKEDAVREAQKELEALIQNLENVVEDYML---- 806
           R++       I  P   D + DL+ + G  + V  A+K LE  +  L+   ED  L    
Sbjct: 495 RRMMQDFDVNISIPPPSD-NSDLVRVTGPPENVERARKALEERVGQLDAEREDRALKGFQ 671

Query: 807 ----VDPKHHRHFVIRRGQVLREIAEEYGGVMVSFP-RSGTQSDKVTLKGAKDCVEAAKK 861
               VDP+HH   + R+G V+ +I  ++  V V FP R+      +T+ G +   + A++
Sbjct: 672 LQVEVDPRHHPKIIGRKGAVISKIRADHD-VNVQFPDRNEENQGLITITGYEQNAQRARE 848

Query: 862 RIQEIIEDLEAQVTVECAIPQKFHRSVMGPKGSRIQQITRDYNVQIKFP 910
            I  I++DLE  VT E  I  + H  ++G KG  +++I  D+NV I+FP
Sbjct: 849 EILGIVKDLEDMVTEEVQIDHRVHPRIIGGKGRTVRRIMDDFNVDIRFP 995

 Score = 68.9 bits (167), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 54/155 (34%), Positives = 79/155 (50%), Gaps = 1/155 (0%)
 Frame = +3

Query: 975  IEVEVPFDLHRYIIGQKGSGIRKMMDEFEVNIHVP-APELQSDTIAITGLAANLDRAKAG 1033
            ++VEV    H  IIG+KG+ I K+  + +VN+  P   E     I ITG   N  RA+  
Sbjct: 672  LQVEVDPRHHPKIIGRKGAVISKIRADHDVNVQFPDRNEENQGLITITGYEQNAQRAREE 851

Query: 1034 LLDRVKELQAEQEDRALRSFKLSVTVDPKYHPKIIGRKGAVITQIRLEHEVNIQFPDKDD 1093
            +L  VK+L    ED         V +D + HP+IIG KG  + +I  +  V+I+FP  D 
Sbjct: 852  ILGIVKDL----EDMVTE----EVQIDHRVHPRIIGGKGRTVRRIMDDFNVDIRFPRSDS 1007

Query: 1094 GNQPQDQITITGYEKNTEAARDAILKIVGELEQMV 1128
            G+   + +TITG E      +D +L +  E  Q V
Sbjct: 1008 GD--PNMVTITGPEDAVYDCKDHLLNLQEEYLQDV 1106

 Score = 50.8 bits (120), Expect(2) = 2e-09,   Method: Compositional matrix adjust.
 Identities = 50/197 (25%), Positives = 87/197 (44%), Gaps = 10/197 (5%)
 Frame = +3

Query: 162 HRFVIGKNGEKL-QDLELKTATKIQIPRPDDPSNQIKITGTKEGIEKAR----HEVLLIS 216
           H +  G++  ++ QD ++     I IP P D S+ +++TG  E +E+AR      V  + 
Sbjct: 468 HHWPEGRDVRRMMQDFDVN----ISIPPPSDNSDLVRVTGPPENVERARKALEERVGQLD 635

Query: 217 AEQDKRAVE----RLEVEKAFHPFIAGPYNRLVGEIMQETGTRINIPPPSV-NRTEIVFT 271
           AE++ RA++    ++EV+   HP I G    ++ +I  +    +  P  +  N+  I  T
Sbjct: 636 AEREDRALKGFQLQVEVDPRHHPKIIGRKGAVISKIRADHDVNVQFPDRNEENQGLITIT 815

Query: 272 GEKEQLAQAVARXXXXXXXXXXXXXXXXXXXXXSQHKYVIGPKGNSLQEILERTGVSVEI 331
           G  EQ AQ                           H  +IG KG +++ I++   V +  
Sbjct: 816 G-YEQNAQRAREEILGIVKDLEDMVTEEVQIDHRVHPRIIGGKGRTVRRIMDDFNVDIRF 992

Query: 332 PPSDSISETVILRGEPE 348
           P SDS    ++    PE
Sbjct: 993 PRSDSGDPNMVTITGPE 1043

 Score = 30.8 bits (68), Expect(2) = 2e-09,   Method: Compositional matrix adjust.
 Identities = 17/47 (36%), Positives = 28/47 (59%), Gaps = 3/47 (6%)
 Frame = +1

Query: 127 IMVSGK---LDAVMKARKDIVARLQTQASATVPIPKEHHRFVIGKNG 170
           I+++GK    +A  KA  D+V       +  VP+P ++HRF+IG+ G
Sbjct: 361 IIITGKPEKCEAAKKALLDLVP-----ITEEVPVPFDYHRFIIGQKG 486

 Score = 61.6 bits (148), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 62/238 (26%), Positives = 106/238 (44%), Gaps = 10/238 (4%)
 Frame = +3

Query: 809  PKHHRHFVIRRGQVLREIAEEYGGVMVSFPRSGTQSDKVTLKGAKDCVEAAKKRIQEIIE 868
            P HH       G+ +R + +++  V +S P     SD V + G  + VE A+K ++E + 
Sbjct: 462  PLHH----WPEGRDVRRMMQDFD-VNISIPPPSDNSDLVRVTGPPENVERARKALEERVG 626

Query: 869  DLEAQ--------VTVECAIPQKFHRSVMGPKGSRIQQITRDYNVQIKFPDR-EENPVHS 919
             L+A+          ++  +  + H  ++G KG+ I +I  D++V ++FPDR EEN    
Sbjct: 627  QLDAEREDRALKGFQLQVEVDPRHHPKIIGRKGAVISKIRADHDVNVQFPDRNEENQGLI 806

Query: 920  VEPSIQENGDEAGEGREAKETDPGSPRRCDIIIISGRXXXXXXXXXXXXXXVPVTIEVEV 979
                 ++N   A               R +I+ I                   VT EV++
Sbjct: 807  TITGYEQNAQRA---------------REEILGIVKDLEDM------------VTEEVQI 905

Query: 980  PFDLHRYIIGQKGSGIRKMMDEFEVNIHVPAPEL-QSDTIAITGLAANLDRAKAGLLD 1036
               +H  IIG KG  +R++MD+F V+I  P  +    + + ITG    +   K  LL+
Sbjct: 906  DHRVHPRIIGGKGRTVRRIMDDFNVDIRFPRSDSGDPNMVTITGPEDAVYDCKDHLLN 1079

 Score = 57.8 bits (138), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 44/170 (25%), Positives = 75/170 (44%), Gaps = 26/170 (15%)
 Frame = +1

Query: 1004 VNIHVPAPELQSDTIAITGLAANLDRAKAGLLDRVKELQAEQEDRALRSFKLSVTVDPKY 1063
            V +  P   ++S+ + I G    ++ AK  + D V +L A+          +   +  +Y
Sbjct: 16   VTVSFPRSGVKSERVVIKGSKDCVEGAKKKITDIVADLDAQ--------VTVECVISQQY 171

Query: 1064 HPKIIGRKGAVITQIRLEHEVNIQFPDK--------------------------DDGNQP 1097
            H  ++G +G+ + +I   HEV I+FPDK                          + G + 
Sbjct: 172  HRTVMGAQGSHVREITRTHEVGIKFPDKPMPNGRQGEGEEEHVANGDVSSEEGSERGTRK 351

Query: 1098 QDQITITGYEKNTEAARDAILKIVGELEQMVSEDVPLDHRVHARIIGARG 1147
             D I ITG  +  EAA+ A+L +V      ++E+VP+    H  IIG +G
Sbjct: 352  SDIIIITGKPEKCEAAKKALLDLV-----PITEEVPVPFDYHRFIIGQKG 486

 Score = 53.9 bits (128), Expect = 4e-07,   Method: Compositional matrix adjust.
 Identities = 27/80 (33%), Positives = 49/80 (61%)
 Frame = +1

Query: 467 VSVRIPPDSEKSNLIRIEGDPQGVQQAKRELLELASRMENERTKDLIIEQRFHRTIIGQK 526
           V+V  P    KS  + I+G    V+ AK+++ ++ + ++ + T + +I Q++HRT++G +
Sbjct: 16  VTVSFPRSGVKSERVVIKGSKDCVEGAKKKITDIVADLDAQVTVECVISQQYHRTVMGAQ 195

Query: 527 GERIREIRDKFPEVIINFPD 546
           G  +REI  +  EV I FPD
Sbjct: 196 GSHVREI-TRTHEVGIKFPD 252

 Score = 51.2 bits (121), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 43/180 (23%), Positives = 77/180 (42%), Gaps = 12/180 (6%)
 Frame = +3

Query: 92  MNQFGEGEQAKICLEIMQRTGAHLELSLAKDQGLSIMVSGKLDAVMKARKDIVARL-QTQ 150
           ++ + EG   +    +MQ    ++ +    D    + V+G  + V +ARK +  R+ Q  
Sbjct: 465 LHHWPEGRDVR---RMMQDFDVNISIPPPSDNSDLVRVTGPPENVERARKALEERVGQLD 635

Query: 151 A----------SATVPIPKEHHRFVIGKNGEKLQDLELKTATKIQIP-RPDDPSNQIKIT 199
           A             V +   HH  +IG+ G  +  +       +Q P R ++    I IT
Sbjct: 636 AEREDRALKGFQLQVEVDPRHHPKIIGRKGAVISKIRADHDVNVQFPDRNEENQGLITIT 815

Query: 200 GTKEGIEKARHEVLLISAEQDKRAVERLEVEKAFHPFIAGPYNRLVGEIMQETGTRINIP 259
           G ++  ++AR E+L I  + +    E ++++   HP I G   R V  IM +    I  P
Sbjct: 816 GYEQNAQRAREEILGIVKDLEDMVTEEVQIDHRVHPRIIGGKGRTVRRIMDDFNVDIRFP 995

 Score = 42.4 bits (98), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 38/166 (22%), Positives = 73/166 (43%), Gaps = 29/166 (17%)
 Frame = +1

Query: 758 GARIIFPAAEDKDQDLITIIGKEDAVREAQKELEALIQNLENVVEDYMLVDPKHHRHFVI 817
           G  + FP +  K + ++ I G +D V  A+K++  ++ +L+  V    ++  ++HR  + 
Sbjct: 13  GVTVSFPRSGVKSERVV-IKGSKDCVEGAKKKITDIVADLDAQVTVECVISQQYHRTVMG 189

Query: 818 RRGQVLREIAEEYGGVMVSFP-----------------------------RSGTQSDKVT 848
            +G  +REI   +  V + FP                             R   +SD + 
Sbjct: 190 AQGSHVREITRTH-EVGIKFPDKPMPNGRQGEGEEEHVANGDVSSEEGSERGTRKSDIII 366

Query: 849 LKGAKDCVEAAKKRIQEIIEDLEAQVTVECAIPQKFHRSVMGPKGS 894
           + G  +  EAAKK + +++      +T E  +P  +HR ++G KG 
Sbjct: 367 ITGKPEKCEAAKKALLDLV-----PITEEVPVPFDYHRFIIGQKGG 489

 Score = 40.0 bits (92), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 26/84 (30%), Positives = 41/84 (48%)
 Frame = +1

Query: 681 EECGGVHIHFPVEGSGSDTVVIRGPSSDVEKAKKQLLHLAEEKQTKSFTVDIRAKPEYHK 740
           EE GGV + FP  G  S+ VVI+G    VE AKK++  +  +   +  TV+     +YH+
Sbjct: 1   EEYGGVTVSFPRSGVKSERVVIKGSKDCVEGAKKKITDIVADLDAQ-VTVECVISQQYHR 177

Query: 741 FLXXXXXXXXRKVRDSTGARIIFP 764
            +        R++  +    I FP
Sbjct: 178 TVMGAQGSHVREITRTHEVGIKFP 249

 Score = 37.0 bits (84), Expect = 0.051,   Method: Compositional matrix adjust.
 Identities = 22/69 (31%), Positives = 36/69 (52%), Gaps = 3/69 (4%)
 Frame = +1

Query: 127 IMVSGKLDAVMKARK---DIVARLQTQASATVPIPKEHHRFVIGKNGEKLQDLELKTATK 183
           +++ G  D V  A+K   DIVA L  Q +    I +++HR V+G  G  ++  E+    +
Sbjct: 58  VVIKGSKDCVEGAKKKITDIVADLDAQVTVECVISQQYHRTVMGAQGSHVR--EITRTHE 231

Query: 184 IQIPRPDDP 192
           + I  PD P
Sbjct: 232 VGIKFPDKP 258
>31560
          Length = 597

 Score =  146 bits (369), Expect(2) = 3e-56,   Method: Compositional matrix adjust.
 Identities = 69/134 (51%), Positives = 100/134 (74%)
 Frame = -3

Query: 490 VQQAKRELLELASRMENERTKDLIIEQRFHRTIIGQKGERIREIRDKFPEVIINFPDPAQ 549
           VQ+AK++LLE++ RMENE+++D+II+QRFH TIIG +GE IREIR++F +V I FPD  +
Sbjct: 403 VQKAKQQLLEMSQRMENEKSRDIIIDQRFHGTIIGARGENIREIRERFNQVQITFPDQGK 224

Query: 550 KSDIVQLRGPKNEVEKCTKYMQKMVADLVENSYSISVPIFKQFHXXXXXXXXXXXXXXRE 609
           KSDIV LRGPK +V+KC K++Q +  +++E++Y   V IFK FH              R+
Sbjct: 223 KSDIVTLRGPKQDVDKCFKHLQVLHKEMLESNYQDKVKIFKDFHXNIIGKGGANIKKIRD 44

Query: 610 ESNTKIDLPAENSN 623
           E+NT+IDLP E+++
Sbjct: 43  ETNTRIDLPGEHAD 2

 Score = 92.4 bits (228), Expect(2) = 3e-56,   Method: Compositional matrix adjust.
 Identities = 44/67 (65%), Positives = 54/67 (80%), Gaps = 1/67 (1%)
 Frame = -1

Query: 427 MVKDLI-NRMDYVEINIDHKFHRHLIGKSGANINRIKDQYKVSVRIPPDSEKSNLIRIEG 485
           +V DL+ NRMDY EI +D KFH+H+IGK+GANI RIKD   VSVRIP D+E SN+IRIEG
Sbjct: 594 IVTDLLSNRMDYAEIEVDPKFHKHIIGKNGANITRIKDDNGVSVRIPSDTENSNVIRIEG 415

Query: 486 DPQGVQQ 492
           DP G ++
Sbjct: 414 DPAGCRR 394

 Score = 72.0 bits (175), Expect = 1e-12,   Method: Compositional matrix adjust.
 Identities = 38/129 (29%), Positives = 64/129 (49%)
 Frame = -3

Query: 637 EAARSRILSIQKDLANIAEVEVSIPAKLHNSLIGTKGRLIRSIMEECGGVHIHFPVEGSG 696
           + A+ ++L + + + N    ++ I  + H ++IG +G  IR I E    V I FP +G  
Sbjct: 400 QKAKQQLLEMSQRMENEKSRDIIIDQRFHGTIIGARGENIREIRERFNQVQITFPDQGKK 221

Query: 697 SDTVVIRGPSSDVEKAKKQLLHLAEEKQTKSFTVDIRAKPEYHKFLXXXXXXXXRKVRDS 756
           SD V +RGP  DV+K  K L  L +E    ++   ++   ++H  +        +K+RD 
Sbjct: 220 SDIVTLRGPKQDVDKCFKHLQVLHKEMLESNYQDKVKIFKDFHXNIIGKGGANIKKIRDE 41

Query: 757 TGARIIFPA 765
           T  RI  P 
Sbjct: 40  TNTRIDLPG 14

 Score = 54.7 bits (130), Expect(2) = 2e-12,   Method: Compositional matrix adjust.
 Identities = 31/90 (34%), Positives = 51/90 (56%), Gaps = 1/90 (1%)
 Frame = -3

Query: 1110 TEAARDAILKIVGELEQMVSEDVPLDHRVHARIIGARGKAIRKIMDEF-KVDIRFPQSGA 1168
             + A+  +L++   +E   S D+ +D R H  IIGARG+ IR+I + F +V I FP  G 
Sbjct: 403  VQKAKQQLLEMSQRMENEKSRDIIIDQRFHGTIIGARGENIREIRERFNQVQITFPDQGK 224

Query: 1169 PDPNCVTVTGLPENVEEAIDHILNLEEEYL 1198
               + VT+ G  ++V++   H+  L +E L
Sbjct: 223  K-SDIVTLRGPKQDVDKCFKHLQVLHKEML 137

 Score = 37.4 bits (85), Expect(2) = 2e-12,   Method: Compositional matrix adjust.
 Identities = 15/33 (45%), Positives = 25/33 (75%)
 Frame = -1

Query: 1057 VTVDPKYHPKIIGRKGAVITQIRLEHEVNIQFP 1089
            + VDPK+H  IIG+ GA IT+I+ ++ V+++ P
Sbjct: 552  IEVDPKFHKHIIGKNGANITRIKDDNGVSVRIP 454

 Score = 70.5 bits (171), Expect = 4e-12,   Method: Compositional matrix adjust.
 Identities = 41/129 (31%), Positives = 74/129 (57%), Gaps = 1/129 (0%)
 Frame = -3

Query: 783 VREAQKELEALIQNLENVVEDYMLVDPKHHRHFVIRRGQVLREIAEEYGGVMVSFPRSGT 842
           V++A+++L  + Q +EN     +++D + H   +  RG+ +REI E +  V ++FP  G 
Sbjct: 403 VQKAKQQLLEMSQRMENEKSRDIIIDQRFHGTIIGARGENIREIRERFNQVQITFPDQGK 224

Query: 843 QSDKVTLKGAKDCVEAAKKRIQEI-IEDLEAQVTVECAIPQKFHRSVMGPKGSRIQQITR 901
           +SD VTL+G K  V+   K +Q +  E LE+    +  I + FH +++G  G+ I++I  
Sbjct: 223 KSDIVTLRGPKQDVDKCFKHLQVLHKEMLESNYQDKVKIFKDFHXNIIGKGGANIKKIRD 44

Query: 902 DYNVQIKFP 910
           + N +I  P
Sbjct: 43  ETNTRIDLP 17

 Score = 45.8 bits (107), Expect(2) = 1e-09,   Method: Compositional matrix adjust.
 Identities = 37/135 (27%), Positives = 62/135 (45%), Gaps = 2/135 (1%)
 Frame = -3

Query: 1032 AGLLDRVKELQAEQEDRALRSFKLSVTVDPKYHPKIIGRKGAVITQIRLE-HEVNIQFPD 1090
            +G + + K+   E   R        + +D ++H  IIG +G  I +IR   ++V I FPD
Sbjct: 412  SGWVQKAKQQLLEMSQRMENEKSRDIIIDQRFHGTIIGARGENIREIRERFNQVQITFPD 233

Query: 1091 KDDGNQPQDQITITGYEKNTEAARDAILKIVGE-LEQMVSEDVPLDHRVHARIIGARGKA 1149
            +    +  D +T+ G +++ +     +  +  E LE    + V +    H  IIG  G  
Sbjct: 232  Q---GKKSDIVTLRGPKQDVDKCFKHLQVLHKEMLESNYQDKVKIFKDFHXNIIGKGGAN 62

Query: 1150 IRKIMDEFKVDIRFP 1164
            I+KI DE    I  P
Sbjct: 61   IKKIRDETNTRIDLP 17

 Score = 36.2 bits (82), Expect(2) = 1e-09,   Method: Compositional matrix adjust.
 Identities = 18/54 (33%), Positives = 31/54 (57%)
 Frame = -1

Query: 976  EVEVPFDLHRYIIGQKGSGIRKMMDEFEVNIHVPAPELQSDTIAITGLAANLDR 1029
            E+EV    H++IIG+ G+ I ++ D+  V++ +P+    S+ I I G  A   R
Sbjct: 555  EIEVDPKFHKHIIGKNGANITRIKDDNGVSVRIPSDTENSNVIRIEGDPAGCRR 394

 Score = 62.0 bits (149), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 40/133 (30%), Positives = 71/133 (53%), Gaps = 5/133 (3%)
 Frame = -3

Query: 345 GEPEKLGQALTEVYAKANSFTVSSVSAPSWLHRFIIGKKGQNLAKITQQMPKVHIEF--- 401
           G  +K  Q L E+  +  +     +      H  IIG +G+N+ +I ++  +V I F   
Sbjct: 409 GWVQKAKQQLLEMSQRMENEKSRDIIIDQRFHGTIIGARGENIREIRERFNQVQITFPDQ 230

Query: 402 TEGEDKITLEGPTEDVNVAQEQIEGMVKDLI--NRMDYVEINIDHKFHRHLIGKSGANIN 459
            +  D +TL GP +DV+   + ++ + K+++  N  D V+I  D  FH ++IGK GANI 
Sbjct: 229 GKKSDIVTLRGPKQDVDKCFKHLQVLHKEMLESNYQDKVKIFKD--FHXNIIGKGGANIK 56

Query: 460 RIKDQYKVSVRIP 472
           +I+D+    + +P
Sbjct: 55  KIRDETNTRIDLP 17

 Score = 53.9 bits (128), Expect = 4e-07,   Method: Compositional matrix adjust.
 Identities = 33/99 (33%), Positives = 55/99 (55%), Gaps = 2/99 (2%)
 Frame = -3

Query: 439 EINIDHKFHRHLIGKSGANINRIKDQY-KVSVRIPPDSEKSNLIRIEGDPQGVQQAKREL 497
           +I ID +FH  +IG  G NI  I++++ +V +  P   +KS+++ + G  Q V +  + L
Sbjct: 340 DIIIDQRFHGTIIGARGENIREIRERFNQVQITFPDQGKKSDIVTLRGPKQDVDKCFKHL 161

Query: 498 LELASRMENERTKDLI-IEQRFHRTIIGQKGERIREIRD 535
             L   M     +D + I + FH  IIG+ G  I++IRD
Sbjct: 160 QVLHKEMLESNYQDKVKIFKDFHXNIIGKGGANIKKIRD 44

 Score = 43.9 bits (102), Expect(2) = 6e-07,   Method: Compositional matrix adjust.
 Identities = 37/162 (22%), Positives = 68/162 (41%), Gaps = 7/162 (4%)
 Frame = -3

Query: 856  VEAAKKRIQEIIEDLEAQVTVECAIPQKFHRSVMGPKGSRIQQITRDYN-VQIKFPDREE 914
            V+ AK+++ E+ + +E + + +  I Q+FH +++G +G  I++I   +N VQI FPD+  
Sbjct: 403  VQKAKQQLLEMSQRMENEKSRDIIIDQRFHGTIIGARGENIREIRERFNQVQITFPDQ-- 230

Query: 915  NPVHSVEPSIQENGDEAGEGREAKETDPGSPRRCDIIIISGRXXXXXXXXXXXXXXVPVT 974
                                           ++ DI+ + G                   
Sbjct: 229  ------------------------------GKKSDIVTLRGPKQDVDKCFKHLQVLHKEM 140

Query: 975  IE------VEVPFDLHRYIIGQKGSGIRKMMDEFEVNIHVPA 1010
            +E      V++  D H  IIG+ G+ I+K+ DE    I +P 
Sbjct: 139  LESNYQDKVKIFKDFHXNIIGKGGANIKKIRDETNTRIDLPG 14

 Score = 29.3 bits (64), Expect(2) = 6e-07,   Method: Compositional matrix adjust.
 Identities = 14/45 (31%), Positives = 24/45 (53%)
 Frame = -1

Query: 807 VDPKHHRHFVIRRGQVLREIAEEYGGVMVSFPRSGTQSDKVTLKG 851
           VDPK H+H + + G  +  I ++  GV V  P     S+ + ++G
Sbjct: 546 VDPKFHKHIIGKNGANITRIKDD-NGVSVRIPSDTENSNVIRIEG 415

 Score = 44.3 bits (103), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 37/135 (27%), Positives = 69/135 (51%), Gaps = 11/135 (8%)
 Frame = -3

Query: 136 VMKARKDIV---ARLQTQASATVPIPKEHHRFVIGKNGEKLQDLELKTATKIQIPRPDD- 191
           V KA++ ++    R++ + S  + I +  H  +IG  GE ++++  +   ++QI  PD  
Sbjct: 403 VQKAKQQLLEMSQRMENEKSRDIIIDQRFHGTIIGARGENIREIR-ERFNQVQITFPDQG 227

Query: 192 -PSNQIKITGTKEGIEKA------RHEVLLISAEQDKRAVERLEVEKAFHPFIAGPYNRL 244
             S+ + + G K+ ++K        H+ +L S  QDK     +++ K FH  I G     
Sbjct: 226 KKSDIVTLRGPKQDVDKCFKHLQVLHKEMLESNYQDK-----VKIFKDFHXNIIGKGGAN 62

Query: 245 VGEIMQETGTRINIP 259
           + +I  ET TRI++P
Sbjct: 61  IKKIRDETNTRIDLP 17

 Score = 35.0 bits (79), Expect = 0.17,   Method: Compositional matrix adjust.
 Identities = 17/64 (26%), Positives = 30/64 (46%)
 Frame = -1

Query: 307 HKYVIGPKGNSLQEILERTGVSVEIPPSDSISETVILRGEPEKLGQALTEVYAKANSFTV 366
           HK++IG  G ++  I +  GVSV IP     S  + + G+P    +     +   N +  
Sbjct: 531 HKHIIGKNGANITRIKDDNGVSVRIPSDTENSNVIRIEGDPAGCRRPSNNCWKCHNGWKT 352

Query: 367 SSVS 370
            S++
Sbjct: 351 RSLA 340

 Score = 33.1 bits (74), Expect = 0.66,   Method: Composition-based stats.
 Identities = 20/74 (27%), Positives = 38/74 (51%), Gaps = 7/74 (9%)
 Frame = -1

Query: 500 LASRMENERTKDLIIEQRFHRTIIGQKGERIREIRDKFPEVIINFPDPAQKSDIVQLRG- 558
           L++RM+     ++ ++ +FH+ IIG+ G  I  I+D    V +  P   + S+++++ G 
Sbjct: 579 LSNRMD---YAEIEVDPKFHKHIIGKNGANITRIKDD-NGVSVRIPSDTENSNVIRIEGD 412

Query: 559 ------PKNEVEKC 566
                 P N   KC
Sbjct: 411 PAGCRRPSNNCWKC 370

 Score = 32.7 bits (73), Expect = 0.87,   Method: Compositional matrix adjust.
 Identities = 15/55 (27%), Positives = 28/55 (50%)
 Frame = -1

Query: 153 ATVPIPKEHHRFVIGKNGEKLQDLELKTATKIQIPRPDDPSNQIKITGTKEGIEK 207
           A + +  + H+ +IGKNG  +  ++      ++IP   + SN I+I G   G  +
Sbjct: 558 AEIEVDPKFHKHIIGKNGANITRIKDDNGVSVRIPSDTENSNVIRIEGDPAGCRR 394
>13631
          Length = 855

 Score = 84.7 bits (208), Expect = 2e-16,   Method: Compositional matrix adjust.
 Identities = 38/77 (49%), Positives = 62/77 (80%), Gaps = 3/77 (3%)
 Frame = +3

Query: 78  QVFHVPLEERKYKDMNQ--FG-EGEQAKICLEIMQRTGAHLELSLAKDQGLSIMVSGKLD 134
           QVF VP+ ER++K++N+  FG E +QAKIC +IM + G  +E+SLA+DQ ++++++G+ D
Sbjct: 501 QVFTVPMVERRFKEVNEHRFGDESDQAKICKDIMAKYGVAIEISLARDQSMTVVINGRSD 680

Query: 135 AVMKARKDIVARLQTQA 151
           +VMKAR+++V +LQTQ 
Sbjct: 681 SVMKARREVVGKLQTQV 731
>09451
          Length = 1994

 Score = 40.4 bits (93), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 22/69 (31%), Positives = 38/69 (55%)
 Frame = -2

Query: 1055 LSVTVDPKYHPKIIGRKGAVITQIRLEHEVNIQFPDKDDGNQPQDQITITGYEKNTEAAR 1114
              ++V+  +  KIIGR G+ I  ++      I+   +DDGN  + ++ +TG E   +AAR
Sbjct: 1885 FDMSVEAHHCGKIIGRGGSKIRDLQTGSGCRIKVSREDDGNGKR-RVELTGSEDQIDAAR 1709

Query: 1115 DAILKIVGE 1123
            D I  ++ E
Sbjct: 1708 DMINSLLAE 1682

 Score = 31.2 bits (69), Expect = 3.0,   Method: Compositional matrix adjust.
 Identities = 25/83 (30%), Positives = 41/83 (49%), Gaps = 2/83 (2%)
 Frame = -2

Query: 510  KDLI-IEQRFHRTIIGQKGERIREIRDKFPEVIINFPDPAQKSDI-VQLRGPKNEVEKCT 567
            KD+I I   F   IIG+ G RIRE+++     I    DP +     V+L G  + +    
Sbjct: 1570 KDMIEINSDFVGRIIGKGGSRIRELQEDTGCRINVSRDPGRDGQTEVELIGSHSAISN-- 1397

Query: 568  KYMQKMVADLVENSYSISVPIFK 590
               ++ +AD+V+ SY     +F+
Sbjct: 1396 --AKRAIADIVDQSY*SPFHVFR 1334
>03467
          Length = 2192

 Score = 38.9 bits (89), Expect = 0.015,   Method: Compositional matrix adjust.
 Identities = 36/152 (23%), Positives = 68/152 (44%), Gaps = 36/152 (23%)
 Frame = -2

Query: 165  VIGKNGEKLQDLELKTATKIQIPRPDDP--SNQIKITGTKEGIEKAR---HEVLLISAEQ 219
            +IG+ G K+++L++++  +I++ R D+P  + ++ ++G+ + I KA+   H+VL    E+
Sbjct: 2020 IIGRGGNKIRELQIESRCQIKVNRDDEPDGTRRVDLSGSDDAIAKAKDMIHQVL----EE 1853

Query: 220  DKRA---------------------------VERLE--VEKAFHPFIAGPYNRLVGEIMQ 250
            D R                             ERL   V+  F   I G     + EI  
Sbjct: 1852 DDRGPRQQSYQQRSYGGGGMGGGYSGGGGGGNERLTMAVDSTFVGRIIGRGGSRIREIQD 1673

Query: 251  ETGTRINIPPPSVN--RTEIVFTGEKEQLAQA 280
             TG R+N+     +  +TE+   G   ++  A
Sbjct: 1672 STGCRVNVSRDGDDNGQTEVELRGTLSEVQHA 1577

 Score = 31.2 bits (69), Expect = 3.1,   Method: Compositional matrix adjust.
 Identities = 26/76 (34%), Positives = 40/76 (52%), Gaps = 3/76 (3%)
 Frame = -2

Query: 506  NERTKDLIIEQRFHRTIIGQKGERIREIRDKFP---EVIINFPDPAQKSDIVQLRGPKNE 562
            NER   + ++  F   IIG+ G RIREI+D       V  +  D  Q    V+LRG  +E
Sbjct: 1759 NERLT-MAVDSTFVGRIIGRGGSRIREIQDSTGCRVNVSRDGDDNGQTE--VELRGTLSE 1589

Query: 563  VEKCTKYMQKMVADLV 578
            V+    + ++M+ D+V
Sbjct: 1588 VQ----HAKQMIDDIV 1553
>09541
          Length = 2010

 Score = 37.4 bits (85), Expect = 0.036,   Method: Compositional matrix adjust.
 Identities = 16/61 (26%), Positives = 37/61 (60%)
 Frame = -1

Query: 155 VPIPKEHHRFVIGKNGEKLQDLELKTATKIQIPRPDDPSNQIKITGTKEGIEKARHEVLL 214
           +P+P++    VIGK GE ++ ++ ++  K+Q  +PDD  ++ ++ G     +K ++ + +
Sbjct: 234 IPVPRQAVGLVIGKGGEMIKKIQNESGAKVQF-KPDDGQSEDRLCGVTGSPDKVQNAISM 58

Query: 215 I 215
           I
Sbjct: 57  I 55
>30669
          Length = 403

 Score = 35.8 bits (81), Expect = 0.11,   Method: Compositional matrix adjust.
 Identities = 13/22 (59%), Positives = 18/22 (81%)
 Frame = -1

Query: 305 SQHKYVIGPKGNSLQEILERTG 326
           +QH+YVIGP+GN +QEI+   G
Sbjct: 388 TQHRYVIGPRGNGIQEIITLMG 323

 Score = 29.6 bits (65), Expect = 8.2,   Method: Compositional matrix adjust.
 Identities = 18/60 (30%), Positives = 30/60 (50%)
 Frame = -1

Query: 376 HRFIIGKKGQNLAKITQQMPKVHIEFTEGEDKITLEGPTEDVNVAQEQIEGMVKDLINRM 435
           HR++IG +G  + +I                 ITL G  E V +A++++E  VKD++  M
Sbjct: 382 HRYVIGPRGNGIQEI-----------------ITLMGKEEGVKMAKQELEKAVKDVLVCM 254

 Score = 29.3 bits (64), Expect = 9.7,   Method: Compositional matrix adjust.
 Identities = 11/27 (40%), Positives = 23/27 (85%)
 Frame = -1

Query: 771 QDLITIIGKEDAVREAQKELEALIQNL 797
           Q++IT++GKE+ V+ A++ELE  ++++
Sbjct: 346 QEIITLMGKEEGVKMAKQELEKAVKDV 266
>26269
          Length = 679

 Score = 32.7 bits (73), Expect = 0.84,   Method: Compositional matrix adjust.
 Identities = 37/144 (25%), Positives = 61/144 (42%), Gaps = 16/144 (11%)
 Frame = -3

Query: 986  YIIGQKGSGIRKMMDEFEVNIHV----PAPELQSDTIAITGLAANLDRAKAGLLDRVKEL 1041
             IIG+ G  IR++ +   V + +     AP      + I+G A    RAK    + V EL
Sbjct: 629  LIIGKGGETIRQLQERAGVKMVMIQDSNAPSAADKPLRISGDAPKCQRAK----EMVIEL 462

Query: 1042 QAEQEDRALRSFK------------LSVTVDPKYHPKIIGRKGAVITQIRLEHEVNIQFP 1089
              E+ D     F             + + V  +    +IG+ G +I +I+ E  V +QF 
Sbjct: 461  LQEKADVPAPGFNNFDNMGPGGPGGIEIPVPRQAVGLVIGKGGEMIKKIQAEMMVKVQF- 285

Query: 1090 DKDDGNQPQDQITITGYEKNTEAA 1113
              DDG   +    +TG+ +  + A
Sbjct: 284  KPDDGQADERICLVTGHPEKVQNA 213

 Score = 32.7 bits (73), Expect = 1.0,   Method: Compositional matrix adjust.
 Identities = 18/61 (29%), Positives = 33/61 (54%)
 Frame = -3

Query: 155 VPIPKEHHRFVIGKNGEKLQDLELKTATKIQIPRPDDPSNQIKITGTKEGIEKARHEVLL 214
           +P+P++    VIGK GE ++ ++ +   K+Q  +PDD     +I       EK ++ V +
Sbjct: 380 IPVPRQAVGLVIGKGGEMIKKIQAEMMVKVQF-KPDDGQADERICLVTGHPEKVQNAVGM 204

Query: 215 I 215
           I
Sbjct: 203 I 201
>04763
          Length = 1073

 Score = 32.7 bits (73), Expect = 0.91,   Method: Compositional matrix adjust.
 Identities = 21/67 (31%), Positives = 39/67 (58%), Gaps = 2/67 (2%)
 Frame = -3

Query: 155 VPIPKEHHRFVIGKNGEKLQDLELKTATKIQIPRPDDPSNQ--IKITGTKEGIEKARHEV 212
           V IPK+    +IGK G ++ ++  ++  +I I      SN+  I I G++E I+ A++ +
Sbjct: 771 VTIPKDMAGAIIGKGGARITEIRRRSGAQIVIDEALPGSNERIISIIGSQEQIQNAQY-M 595

Query: 213 LLISAEQ 219
           L +S +Q
Sbjct: 594 LQLSVKQ 574
>18876
          Length = 587

 Score = 31.6 bits (70), Expect = 2.0,   Method: Compositional matrix adjust.
 Identities = 19/61 (31%), Positives = 32/61 (52%)
 Frame = +2

Query: 155 VPIPKEHHRFVIGKNGEKLQDLELKTATKIQIPRPDDPSNQIKITGTKEGIEKARHEVLL 214
           +P+P++    VIGK GE  Q ++ +   K+Q  +PDD     +I       EK ++ V +
Sbjct: 365 IPVPRQAVGLVIGKGGEHDQKIQAEMMVKVQF-KPDDGQADERICLVTGHPEKVQNAVGM 541

Query: 215 I 215
           I
Sbjct: 542 I 544
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|93587673|ref|NP_001035277.1| DEAD box polypeptide 17
isoform 4 [Mus musculus]
         (650 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

04883                                                                 462   e-130
09327                                                                 376   e-104
00621                                                                 289   2e-78
01517                                                                 216   3e-56
30136                                                                 213   2e-55
01062                                                                 189   4e-48
09316                                                                 166   2e-41
02054                                                                  99   7e-35
19172                                                                 144   1e-34
00162                                                                 117   1e-31
07310                                                                 126   3e-29
00739                                                                 124   1e-28
12121                                                                 123   3e-28
33025                                                                 111   1e-24
22006                                                                 110   2e-24
34134                                                                  96   4e-23
17544                                                                  95   8e-20
14337                                                                  91   1e-18
08036                                                                  60   3e-18
34295                                                                  87   3e-17
19525                                                                  85   8e-17
17708                                                                  84   2e-16
19640                                                                  79   7e-15
02498                                                                  77   2e-14
11160                                                                  70   2e-14
00617                                                                  77   3e-14
12995                                                                  75   6e-14
11624                                                                  71   1e-12
39583                                                                  69   7e-12
10649                                                                  62   5e-10
03381                                                                  60   3e-09
31899                                                                  57   3e-08
31220                                                                  54   3e-07
19151                                                                  52   6e-07
33083                                                                  48   2e-05
11423                                                                  43   4e-04
06438                                                                  43   4e-04
01821                                                                  39   0.007
27757                                                                  31   1.7  
>04883
          Length = 1155

 Score =  462 bits (1188), Expect = e-130,   Method: Compositional matrix adjust.
 Identities = 210/306 (68%), Positives = 252/306 (82%)
 Frame = +3

Query: 34  PGERLRKKKWDLSELPKFEKNFYVEHPEVARLTPYEVDELRRKKEITVRGGDVCPKPVFA 93
           PG  LRK KWD+S+L  F+KNFY E P  A   P E+DE R+  +I+V  G   P P+  
Sbjct: 189 PGGNLRKPKWDMSKLTPFQKNFYKESPTTASRNPMELDEYRQSHQISV-SGKFVPNPILT 365

Query: 94  FHHANFPQYVMDVLMDQHFTEPTPIQCQGFPLALSGRDMVGIAQTGSGKTLAYLLPAIVH 153
           F   NFP YVM+ +    +T PTPIQ Q +P+A++G+D+VGIAQTGSGKTLA++LPAIVH
Sbjct: 366 FTEVNFPDYVMNQVRRNSWTAPTPIQSQSWPVAMAGKDLVGIAQTGSGKTLAFMLPAIVH 545

Query: 154 INHQPYLERGDGPICLVLAPTRELAQQVQQVADDYGKCSRLKSTCIYGGAPKGPQIRDLE 213
           INHQ YLERGDGPI L L PTRELAQQVQ+VA ++G  SR++S C+YGGAP+GPQ+RDLE
Sbjct: 546 INHQAYLERGDGPIVLALVPTRELAQQVQEVAQEFGHASRVRSVCVYGGAPRGPQLRDLE 725

Query: 214 RGVEICIATPGRLIDFLESGKTNLRRCTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQT 273
           RG EICIATPGRLIDFLES +TNLRRCTYLVLDEADRMLDMGFEPQIRKI++QIRPDRQT
Sbjct: 726 RGAEICIATPGRLIDFLESNRTNLRRCTYLVLDEADRMLDMGFEPQIRKIIEQIRPDRQT 905

Query: 274 LMWSATWPKEVRQLAEDFLRDYTQINVGNLELSANHNILQIVDVCMESEKDHKLIQLMEE 333
           LMWSATWPKEVR+LAEDF+ +Y Q+N+G LEL+ANHNILQI+DVCME EK+ KL++L+ E
Sbjct: 906 LMWSATWPKEVRKLAEDFIDEYVQVNIGALELTANHNILQIIDVCMEHEKEDKLVKLLNE 1085

Query: 334 IMAEKE 339
           IM  K+
Sbjct: 1086IMTRKK 1103
>09327
          Length = 1087

 Score =  376 bits (965), Expect = e-104,   Method: Compositional matrix adjust.
 Identities = 171/234 (73%), Positives = 204/234 (87%)
 Frame = +2

Query: 170 VLAPTRELAQQVQQVADDYGKCSRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDF 229
           +L PTRELAQQVQ+VA ++G  SR++S C+YGGA +GPQ+R+L+RG EICIATPGRLIDF
Sbjct: 20  LLVPTRELAQQVQEVAVEFGHSSRVRSVCVYGGAQRGPQLRELDRGAEICIATPGRLIDF 199

Query: 230 LESGKTNLRRCTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAE 289
           LES +TNLRRCTYLVLDEADRMLDMGFEPQIRKIV+QIRPDRQTLMWSATWPKEVR+LAE
Sbjct: 200 LESNRTNLRRCTYLVLDEADRMLDMGFEPQIRKIVEQIRPDRQTLMWSATWPKEVRKLAE 379

Query: 290 DFLRDYTQINVGNLELSANHNILQIVDVCMESEKDHKLIQLMEEIMAEKENKTIIFVETK 349
           DF+ +YTQIN+G L+L+ANHNILQI+DVCM+ EK+ KL++L+ EIM EKEN+T+IFVETK
Sbjct: 380 DFIMEYTQINIGALQLTANHNILQIIDVCMDHEKEEKLVKLLNEIMQEKENRTLIFVETK 559

Query: 350 XXXXXXXXXXXXXGWPAMCIHGDKSQPERDWVLNEFRSGKAPILIATDVASRGL 403
                        GWP +CIHGDKSQ ERDWVLN+FR+G+ P+L+ATDVASRGL
Sbjct: 560 RKCDDIHRRMKRDGWPVLCIHGDKSQQERDWVLNDFRNGRCPVLLATDVASRGL 721
>00621
          Length = 2263

 Score =  289 bits (740), Expect = 2e-78,   Method: Compositional matrix adjust.
 Identities = 164/445 (36%), Positives = 252/445 (56%), Gaps = 29/445 (6%)
 Frame = +1

Query: 29  KKFGNPGERLRKKKWDLSELPKFEKNFYVEHPEVARLTPYEVDELRRKKEITVRGGDVCP 88
           K+  N  ++  K+KWD       ++++  +  E      + +   R    I+ +GG + P
Sbjct: 94  KRLKNMAKKEAKQKWD-------DRHWTDKAKEEMAERDWRI--FREDYNISCKGGRI-P 243

Query: 89  KPVFAFHHANFPQYVMDVLMDQHFTEPTPIQCQGFPLALSGRDMVGIAQTGSGKTLAYLL 148
            P+  +  ++    +M+V+    + EPTPIQ Q  P+ L  RD++G+A+TGSGKT A+L+
Sbjct: 244 NPIRFWKESDLGADIMEVIDRVGYKEPTPIQMQAIPIGLQNRDIIGVAETGSGKTAAFLI 423

Query: 149 PAIVHINHQPYLERGD----GPICLVLAPTRELAQQVQQVADDYGKCSRLKSTCIYGGAP 204
           P +V I   P +ER +    GP  ++LAPTRELAQQ+++    +G+   ++   + GG  
Sbjct: 424 PLLVWIQSLPKIERLEDADQGPYAVILAPTRELAQQIEEETRKFGEGLGIRVVSVIGGIS 603

Query: 205 KGPQIRDLERGVEICIATPGRLIDFLESGKTNLRRCTYLVLDEADRMLDMGFEPQIRKIV 264
           +  Q   L++G E+ IATPGR+ID LE+    L +CTY+V+DEADRM++MGFEP++RKI+
Sbjct: 604 REEQGFKLQQGCEVVIATPGRMIDVLENRYLVLNQCTYVVMDEADRMINMGFEPEVRKIL 783

Query: 265 DQI-----RPD--------------------RQTLMWSATWPKEVRQLAEDFLRDYTQIN 299
           D +     +PD                    RQT+M++AT P +V +LA  FLR  T + 
Sbjct: 784 DYLPVSNQKPDNDDAEDDLKMLQNFKSKHKYRQTVMFTATMPPQVERLARTFLRRPTVVY 963

Query: 300 VGNLELSANHNILQIVDVCMESEKDHKLIQLMEEIMAEKENKTIIFVETKXXXXXXXXXX 359
           +GN+       + QIV +  ESEK  KLI+++    A  +   IIFV  K          
Sbjct: 964 IGNVGKPVER-VEQIVYMLTESEKRKKLIEVLN---AGVDPPIIIFVNQKKGADVLAKSL 1131

Query: 360 XXXGWPAMCIHGDKSQPERDWVLNEFRSGKAPILIATDVASRGLDVEDVKFVINYDYPNS 419
              G+ A  +HG K Q +R++ L   + G   I++ATDVA RG+D++DV  V+NYD   +
Sbjct: 1132EKMGFNATTLHGGKGQEQREYALASLKGGAKDIMVATDVAGRGIDIKDVSLVLNYDMART 1311

Query: 420 SEDYVHRIGRTARSTNKGTAYTFFT 444
            EDY HRIGRT R+  +GT+ TF T
Sbjct: 1312IEDYTHRIGRTGRAGKEGTSITFLT 1386
>01517
          Length = 2605

 Score =  216 bits (550), Expect = 3e-56,   Method: Compositional matrix adjust.
 Identities = 118/243 (48%), Positives = 155/243 (63%), Gaps = 4/243 (1%)
 Frame = +2

Query: 227 IDFLESGKTNLRRCTYLVLDEADRMLDMGFEPQIRKIV--DQIRP--DRQTLMWSATWPK 282
           +D +E GK  +  C YLVLDEADRMLDMGFEPQIR+IV  D + P   RQTLM+SAT+PK
Sbjct: 2   VDMMERGKIGMDHCNYLVLDEADRMLDMGFEPQIRRIVEKDTMPPTGQRQTLMFSATFPK 181

Query: 283 EVRQLAEDFLRDYTQINVGNLELSANHNILQIVDVCMESEKDHKLIQLMEEIMAEKENKT 342
           E++ LA DFL +Y  + VG +  S + NI Q V    E EK   L+ L+       E+ T
Sbjct: 182 EIQLLARDFLDNYIFLAVGRVG-STSENITQKVVWVEEPEKRSFLLDLLMASGTGPESLT 358

Query: 343 IIFVETKXXXXXXXXXXXXXGWPAMCIHGDKSQPERDWVLNEFRSGKAPILIATDVASRG 402
           ++FVETK              +PA  IHGD+SQ ER+  L  F++G  PIL+AT VA+RG
Sbjct: 359 LVFVETKKGADSLEQFLMYENYPATSIHGDRSQREREDALRVFKNGDRPILVATAVAARG 538

Query: 403 LDVEDVKFVINYDYPNSSEDYVHRIGRTARSTNKGTAYTFFTPGNLKQARELIKVLEEAN 462
           LD+ +V+ VIN+D P+  E+YVHRIGRT R  N G A +FF   N   AR+++ +L EAN
Sbjct: 539 LDIPNVRHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNDKNRNIARDMLDLLTEAN 718

Query: 463 QAI 465
           Q +
Sbjct: 719 QEV 727
>30136
          Length = 524

 Score =  213 bits (542), Expect = 2e-55,   Method: Compositional matrix adjust.
 Identities = 104/175 (59%), Positives = 130/175 (74%)
 Frame = +2

Query: 48  LPKFEKNFYVEHPEVARLTPYEVDELRRKKEITVRGGDVCPKPVFAFHHANFPQYVMDVL 107
           L  F++NFY EHP VA  TPYEV   R + EITVRG      P+  F  A  P YV+  +
Sbjct: 5   LTPFKRNFYQEHPTVANRTPYEVQRYRDEHEITVRGQ--AANPIQDFAEAYLPDYVIKEI 178

Query: 108 MDQHFTEPTPIQCQGFPLALSGRDMVGIAQTGSGKTLAYLLPAIVHINHQPYLERGDGPI 167
             Q +  PTPIQ QG+P+A+SG + VGIA+TGSGKTL Y+LPAIVHIN+Q  L+RG+GPI
Sbjct: 179 RRQGYKSPTPIQAQGWPIAMSGANFVGIAKTGSGKTLGYILPAIVHINNQQPLQRGEGPI 358

Query: 168 CLVLAPTRELAQQVQQVADDYGKCSRLKSTCIYGGAPKGPQIRDLERGVEICIAT 222
            LVLAPTRELAQQ+QQVA ++G  S +++TC++GGAPKG Q+RDL+RG EI IAT
Sbjct: 359 ALVLAPTRELAQQIQQVATEFGSSSYVRNTCVFGGAPKGGQMRDLQRGCEIVIAT 523
>01062
          Length = 2138

 Score =  189 bits (479), Expect = 4e-48,   Method: Compositional matrix adjust.
 Identities = 113/343 (32%), Positives = 174/343 (50%)
 Frame = -3

Query: 112  FTEPTPIQCQGFPLALSGRDMVGIAQTGSGKTLAYLLPAIVHINHQPYLERGDGPICLVL 171
            F +P+ IQ +     + GRD++  AQ+G+GKT  + +  +  ++ Q    +      L+L
Sbjct: 2019 FEKPSAIQQRAVKPIVKGRDVIAQAQSGTGKTATFSISVLQCLDIQLRETQA-----LIL 1855

Query: 172  APTRELAQQVQQVADDYGKCSRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLE 231
            +PTRELA Q+Q+V    G    ++     GG   G  IR L+ G  I   TPGR+ D ++
Sbjct: 1854 SPTRELATQIQKVMLALGDYMNVQCHSCIGGTNIGEDIRKLDYGQHIVSGTPGRVFDMIK 1675

Query: 232  SGKTNLRRCTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDF 291
                  R    ++LDEAD ML+ GF+ QI  +   + P  Q ++ SAT P E+ ++   F
Sbjct: 1674 RRNLRTRSIKMMILDEADEMLNKGFKEQIYDVYRYLPPATQVILISATLPHEILEMTNKF 1495

Query: 292  LRDYTQINVGNLELSANHNILQIVDVCMESEKDHKLIQLMEEIMAEKENKTIIFVETKXX 351
            + D  +I V   EL+        V V  E  K   L  L + +      + +IF  TK  
Sbjct: 1494 MTDPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTI---TQAVIFCNTKRK 1324

Query: 352  XXXXXXXXXXXGWPAMCIHGDKSQPERDWVLNEFRSGKAPILIATDVASRGLDVEDVKFV 411
                        +    +HGD  Q ER+ ++  FR+G + +LI TDV +RG+DV+ V  V
Sbjct: 1323 VDWLTEKMREANFTVSSMHGDMPQKEREAIMKVFRAGDSRVLITTDVWARGIDVQQVSLV 1144

Query: 412  INYDYPNSSEDYVHRIGRTARSTNKGTAYTFFTPGNLKQAREL 454
            INYD PN+ E Y+HRIGR+ R   KG A  F    +++  R++
Sbjct: 1143 INYDLPNNRELYIHRIGRSGRFGRKGVAINFVKNDDIRILRDI 1015
>09316
          Length = 2312

 Score =  166 bits (421), Expect = 2e-41,   Method: Compositional matrix adjust.
 Identities = 114/391 (29%), Positives = 194/391 (49%), Gaps = 17/391 (4%)
 Frame = +2

Query: 74   RRKKEITVRGG--------DVCPKPVFAFHHANFPQYVMD-----VLMDQHFTEPTPIQC 120
            RR+ E  V G         DV    V + H + F  +++       ++D  F  P+ +Q 
Sbjct: 755  RRRNETAVDGAGGEGQAKKDVKGTYV-SIHSSGFRDFLLKPELLRAIIDCGFEHPSEVQH 931

Query: 121  QGFPLALSGRDMVGIAQTGSGKTLAYLLPAIVHINHQPYLERGDGPI-CLVLAPTRELAQ 179
            +  P A+   D++  A++G GKT  ++L  +        LE  DG +  LV+A TRELA 
Sbjct: 932  ECIPQAILSMDVLCQAKSGMGKTAVFVLATL------QQLEPVDGQVSVLVMAHTRELAF 1093

Query: 180  QVQQVADDYGK-CSRLKSTCIYGGAPKGPQIRDLERGV-EICIATPGRLIDFLESGKTNL 237
            Q+ +  + + K  + +K    +GG         L +    I + TPGRL    ++   NL
Sbjct: 1094 QISKEYERFSKYMNNVKIAVFFGGMSVKKDEEVLSKNCPHIVVGTPGRLHALAKANNLNL 1273

Query: 238  RRCTYLVLDEADRML-DMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLRDYT 296
            ++  + +LDE D+ML D+     +++I      ++Q +M+SAT  KE+R + + F++D  
Sbjct: 1274 KKIKHFILDECDKMLADLDMRRDVQEIFRLTPHEKQVMMFSATLSKEIRPICKKFMQDPM 1453

Query: 297  QINVGNLELSANHNILQIVDVCMESEKDHKLIQLMEEIMAEKENKTIIFVETKXXXXXXX 356
            ++ V +      H + Q      ++EK+ KL +L++ +   + N+ IIFV++        
Sbjct: 1454 EVYVDDDSKLTLHGLQQHYCKLKDNEKNRKLFELLDVL---EFNQVIIFVKSVPRCMALS 1624

Query: 357  XXXXXXGWPAMCIHGDKSQPERDWVLNEFRSGKAPILIATDVASRGLDVEDVKFVINYDY 416
                   +PA+ IH   +Q ER     +F+  +  IL+AT++  RG+D+E V  V NYD 
Sbjct: 1625 QLLLEQNFPAIAIHRQMTQEERLSRYQQFKDFQKRILVATNLFGRGMDIERVNIVFNYDM 1804

Query: 417  PNSSEDYVHRIGRTARSTNKGTAYTFFTPGN 447
            P  S+ Y+HR+ R  R   KG A TF +  N
Sbjct: 1805 PEDSDTYLHRVARAGRFGTKGLAITFVSDEN 1897
>02054
          Length = 1110

 Score = 99.4 bits (246), Expect(2) = 7e-35,   Method: Compositional matrix adjust.
 Identities = 63/172 (36%), Positives = 85/172 (49%), Gaps = 7/172 (4%)
 Frame = -3

Query: 280 WPKEVRQLAEDFLRDYTQINVGNLELSANHNILQIVDVCMESE-------KDHKLIQLME 332
           WPK    L    LRD  ++ V N          Q VD   +S        KD  L+ ++ 
Sbjct: 793 WPK----LQRASLRDPVKVEVSNK--------YQTVDTLQQSYLFIPAKYKDAYLVSILN 650

Query: 333 EIMAEKENKTIIFVETKXXXXXXXXXXXXXGWPAMCIHGDKSQPERDWVLNEFRSGKAPI 392
           E+     N  ++F  T              G+ A+ +HG  SQ +R   LN+F+S    I
Sbjct: 649 ELAG---NSFMVFCSTCANTQRVALLLRNLGFTAIPLHGQMSQAKRLGSLNKFKSKDRSI 479

Query: 393 LIATDVASRGLDVEDVKFVINYDYPNSSEDYVHRIGRTARSTNKGTAYTFFT 444
           LIATDVASRGLD+  V  V+N D P  S+DY+HR+GRTAR+   G A TF +
Sbjct: 478 LIATDVASRGLDIPHVDVVLNLDIPTHSKDYMHRVGRTARAGRSGRAITFVS 323

 Score = 67.0 bits (162), Expect(2) = 7e-35,   Method: Compositional matrix adjust.
 Identities = 34/68 (50%), Positives = 48/68 (70%), Gaps = 1/68 (1%)
 Frame = -2

Query: 218 ICIATPGRLIDFLESGK-TNLRRCTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMW 276
           I IATPGRL+D LE+ K  +LR   +LV+DEADR+LDM F+ ++ KI+  I  +R T ++
Sbjct: 995 IIIATPGRLVDHLENTKGFSLRALKFLVMDEADRILDMNFQDEVDKILKVIPRERNTYLF 816

Query: 277 SATWPKEV 284
           SAT   +V
Sbjct: 815 SATMTNKV 792
>19172
          Length = 484

 Score =  144 bits (363), Expect = 1e-34,   Method: Composition-based stats.
 Identities = 70/114 (61%), Positives = 83/114 (72%)
 Frame = -1

Query: 290 DFLRDYTQINVGNLELSANHNILQIVDVCMESEKDHKLIQLMEEIMAEKENKTIIFVETK 349
           +FL +Y Q+N+G+L LSANHNILQIVDVC ESEK  KLIQL+ +I  E E KTIIFVETK
Sbjct: 484 EFLNNYIQVNIGSLSLSANHNILQIVDVCDESEKIAKLIQLLTQISGENETKTIIFVETK 305

Query: 350 XXXXXXXXXXXXXGWPAMCIHGDKSQPERDWVLNEFRSGKAPILIATDVASRGL 403
                        GW A  IHGDKSQ ERD+VL+ FR+G+  IL+ATDVA+RGL
Sbjct: 304 KRVDEITRNISRQGWRACAIHGDKSQQERDFVLSSFRNGRHSILVATDVAARGL 143
>00162
          Length = 2322

 Score =  117 bits (294), Expect(2) = 1e-31,   Method: Compositional matrix adjust.
 Identities = 91/282 (32%), Positives = 130/282 (46%), Gaps = 4/282 (1%)
 Frame = +3

Query: 169 LVLAPTRELAQQVQQVADDYGKCSRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLID 228
           L++ PTRELA Q+ +V +         +  + GG     +   L     I I T GRL+ 
Sbjct: 147 LIITPTRELAFQIYEVLNKIRTFHDFSANLVIGGKFMWRET-HLMGKTNIVICTVGRLLH 323

Query: 229 FLESGKT-NLRRCTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQL 287
            LES +  ++     LVLDEADR++D  F   +  I+  + P RQTL++SAT    V+ L
Sbjct: 324 HLESTQAFDVSELKVLVLDEADRIMDSKFAQDMDSIMSHL-PPRQTLLFSATQTMSVKTL 500

Query: 288 AEDFLRDYTQINVG-NLELSANHNILQIVDVCMESEKDHKLIQLMEEIMAEKENKTIIFV 346
           A   L+D + ++V  + E      + Q   VC   E   KL  L   +     NK ++F+
Sbjct: 501 ARLSLKDPSYVSVDRHAEYVTPTGLEQSYIVC---ELHEKLSLLYSFLKNHPNNKIMVFL 671

Query: 347 ET--KXXXXXXXXXXXXXGWPAMCIHGDKSQPERDWVLNEFRSGKAPILIATDVASRGLD 404
           +T  +             G   + +HG   Q  R  +  EF   +  ILI TD+A RGLD
Sbjct: 672 QTCKQARYVHTVIKRERPGMSVLVLHGGIPQLRRLDIYREFCRKQHVILITTDLACRGLD 851

Query: 405 VEDVKFVINYDYPNSSEDYVHRIGRTARSTNKGTAYTFFTPG 446
              V +VI  D P     Y+HR GRTAR    G A     P 
Sbjct: 852 FPAVNWVIQLDCPVDVNTYIHRAGRTARFECNGQALLVLLPS 977

 Score = 37.4 bits (85), Expect(2) = 1e-31,   Method: Compositional matrix adjust.
 Identities = 18/42 (42%), Positives = 27/42 (64%)
 Frame = +2

Query: 125 LALSGRDMVGIAQTGSGKTLAYLLPAIVHINHQPYLERGDGP 166
           LA  G D++G A+TGSGKTLA+L+P +  ++ Q  +    G 
Sbjct: 20  LACRGLDVLGAAKTGSGKTLAFLIPILETLSKQDIISIWHGS 145
>07310
          Length = 712

 Score =  126 bits (316), Expect = 3e-29,   Method: Compositional matrix adjust.
 Identities = 73/243 (30%), Positives = 120/243 (49%)
 Frame = +2

Query: 225 RLIDFLESGKTNLRRCTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEV 284
           R++D +         C  LVLDEAD++L   F+  +  I+  + P RQ L++SAT+P  V
Sbjct: 2   RILDLMNKRLVKPDTCGILVLDEADKLLSQDFKGMLDNIIAHLPPQRQILLYSATFPLSV 181

Query: 285 RQLAEDFLRDYTQINVGNLELSANHNILQIVDVCMESEKDHKLIQLMEEIMAEKENKTII 344
            Q  + +L++  +IN+  +E      + Q      E +K H L  L  ++     N++II
Sbjct: 182 EQFMKKYLKNPYEINL--MEELTLKGVTQYYAFVQEKQKVHCLNTLFSKLQI---NQSII 346

Query: 345 FVETKXXXXXXXXXXXXXGWPAMCIHGDKSQPERDWVLNEFRSGKAPILIATDVASRGLD 404
           F  +              G+    IH   +Q  R+ V ++FR G    L+ +D+ +RG+D
Sbjct: 347 FCNSTQRVELLAKKITELGYSCYYIHAKMNQQHRNRVFHDFRQGLCRNLVCSDLFTRGID 526

Query: 405 VEDVKFVINYDYPNSSEDYVHRIGRTARSTNKGTAYTFFTPGNLKQARELIKVLEEANQA 464
           ++ V  VIN+D+P  +E Y+HRIGR+ R  + G A    T    +    L K+ +E    
Sbjct: 527 IQAVNVVINFDFPKHAETYLHRIGRSGRYGHLGVAINLIT---FEDRFSLHKIEQELGTE 697

Query: 465 INP 467
           I P
Sbjct: 698 IKP 706
>00739
          Length = 1313

 Score =  124 bits (311), Expect = 1e-28,   Method: Compositional matrix adjust.
 Identities = 85/254 (33%), Positives = 133/254 (52%), Gaps = 2/254 (0%)
 Frame = +3

Query: 208 QIRDLERGVEICIATPGRLIDFLESGKT-NLRRCTYLVLDEADRMLDMGFEPQIRKIVDQ 266
           Q +DL     I I+TPGRL D ++S  T +L+R  +LV+DEADR+LD  F  Q+  I+ +
Sbjct: 18  QGQDLAVKPHIVISTPGRLADHIDSCDTFSLKRVKFLVMDEADRLLDDNFGAQLEPILTR 197

Query: 267 IRPDRQTLMWSATWPKEVRQLAEDFLRDYTQINVGNLELSANHNILQIVDVCMESEKDHK 326
           +   RQTL++SAT    V  L +  L +   + +   E +    + +   +   S KD  
Sbjct: 198 LPSARQTLLFSATLSPTVNALRDSVL-NKPFVWIQQSERATVDELQEDYVLVPASMKDAY 374

Query: 327 LIQLMEEIMAEK-ENKTIIFVETKXXXXXXXXXXXXXGWPAMCIHGDKSQPERDWVLNEF 385
           ++ +++  + +   +  IIF  T               +    +H    Q  R   L+ F
Sbjct: 375 MVHILDHWLKDHPRSSLIIFTXTCKYAQILGMMLEKLQFSCAVLHSMIPQRFRLSSLSRF 554

Query: 386 RSGKAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYVHRIGRTARSTNKGTAYTFFTP 445
           +S +  ILI+TDVASRGLD+  V  +IN++ PN   DYVHR+GRTAR+   G + +  T 
Sbjct: 555 KSNQTRILISTDVASRGLDIPTVDLIINHNIPNRPRDYVHRVGRTARAGRCGQSISLVTE 734

Query: 446 GNLKQARELIKVLE 459
            ++K    LIK +E
Sbjct: 735 FDIK----LIKSIE 764
>12121
          Length = 465

 Score =  123 bits (308), Expect = 3e-28,   Method: Compositional matrix adjust.
 Identities = 56/108 (51%), Positives = 72/108 (66%)
 Frame = -2

Query: 34  PGERLRKKKWDLSELPKFEKNFYVEHPEVARLTPYEVDELRRKKEITVRGGDVCPKPVFA 93
           PG  LRK KWDLS+L +FEK+FY E P VA   P ++ E R   +IT+  G   P P+  
Sbjct: 323 PGANLRKPKWDLSKLVRFEKHFYKEAPSVANRNPIQIQEFRNNNQITL-SGRYLPNPILT 147

Query: 94  FHHANFPQYVMDVLMDQHFTEPTPIQCQGFPLALSGRDMVGIAQTGSG 141
           F  AN P YVM  +   ++T PTPIQ Q +P+A+SG+D+VGIAQTGSG
Sbjct: 146 FEEANLPDYVMSQIHRNNWTSPTPIQSQSWPIAMSGKDLVGIAQTGSG 3

 Score = 86.7 bits (213), Expect = 3e-17,   Method: Composition-based stats.
 Identities = 47/87 (54%), Positives = 52/87 (59%), Gaps = 13/87 (14%)
 Frame = -3

Query: 218 ICIATPGRLIDFLESGKTNLRRCTYLVLDEADRMLDMGFEPQIRKIVDQ---IRPDRQTL 274
           ICIATPGRLIDFLES +TNLRRCTYLVLDEADRMLDMGF P  R    +     P   + 
Sbjct: 463 ICIATPGRLIDFLESNRTNLRRCTYLVLDEADRMLDMGFXPP*RACSLEPTCASPSGTSP 284

Query: 275 MWSA----------TWPKEVRQLAEDF 291
            WSA           WP E +   + F
Sbjct: 283 NWSALRNTSTKRLLVWPIETQYRYKSF 203
>33025
          Length = 558

 Score =  111 bits (277), Expect = 1e-24,   Method: Compositional matrix adjust.
 Identities = 58/155 (37%), Positives = 95/155 (61%), Gaps = 4/155 (2%)
 Frame = +3

Query: 188 YGKCSRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLESGKTNLRRCTYLVLDE 247
           + + + +  + +YG   +  Q   + +G  + + TPGRL+DF+     +L +C YL+LDE
Sbjct: 24  FSRGTDVHPSVVYGATDRRYQKSRIMKGANLVVGTPGRLLDFIGDQTISLGKCQYLILDE 203

Query: 248 ADRMLDMGFEPQIRKIVDQI----RPDRQTLMWSATWPKEVRQLAEDFLRDYTQINVGNL 303
           ADRMLDMGFEP+IRK+VD      +  RQTLM+SAT+ +++++LA DFL DY  I VG +
Sbjct: 204 ADRMLDMGFEPEIRKLVDTHGMPPKTQRQTLMFSATFKEDIQRLAGDFLNDYLFITVGIV 383

Query: 304 ELSANHNILQIVDVCMESEKDHKLIQLMEEIMAEK 338
             + +      ++V    ++DH L +++ E+   K
Sbjct: 384 GGACSDVTQTFLEVDRLQKRDH-LCEILNEMGTAK 485
>22006
          Length = 3414

 Score =  110 bits (275), Expect = 2e-24,   Method: Compositional matrix adjust.
 Identities = 57/140 (40%), Positives = 82/140 (58%)
 Frame = +2

Query: 115  PTPIQCQGFPLALSGRDMVGIAQTGSGKTLAYLLPAIVHINHQPYLERGDGPICLVLAPT 174
            PTPIQ +  P+ + G+DMV +A+TGSGKT A+L+P +  +     +    G   L+L+PT
Sbjct: 3005 PTPIQRKTIPVIMEGKDMVAMARTGSGKTAAFLVPMLERLK----MHSSKGARALILSPT 3172

Query: 175  RELAQQVQQVADDYGKCSRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLESGK 234
            RELA Q  +   + GK   L++  I GG     Q   L +  +I IATPGRL+  L   K
Sbjct: 3173 RELALQTLKFTKELGKFLDLRAAVILGGDRMEDQFSALHQNPDIIIATPGRLLHVLVEMK 3352

Query: 235  TNLRRCTYLVLDEADRMLDM 254
             +L+   Y+V DEADR+ +M
Sbjct: 3353 KSLKEVIYVVFDEADRLFEM 3412
>34134
          Length = 271

 Score = 95.5 bits (236), Expect(2) = 4e-23,   Method: Composition-based stats.
 Identities = 42/51 (82%), Positives = 47/51 (92%)
 Frame = +3

Query: 124 PLALSGRDMVGIAQTGSGKTLAYLLPAIVHINHQPYLERGDGPICLVLAPT 174
           P+A+SGRD VGIAQTGSGKTL+++LPAIVHINHQP LERGDGPI LVL PT
Sbjct: 87  PIAMSGRDCVGIAQTGSGKTLSFILPAIVHINHQPTLERGDGPIALVLVPT 239

 Score = 31.2 bits (69), Expect(2) = 4e-23,   Method: Composition-based stats.
 Identities = 14/29 (48%), Positives = 16/29 (55%)
 Frame = +1

Query: 97  ANFPQYVMDVLMDQHFTEPTPIQCQGFPL 125
           A FP YVM  +    +  PT IQ QG PL
Sbjct: 7   ACFPDYVMQQIHKNSWVSPTAIQSQGCPL 93
>17544
          Length = 1047

 Score = 95.1 bits (235), Expect = 8e-20,   Method: Compositional matrix adjust.
 Identities = 52/145 (35%), Positives = 76/145 (52%), Gaps = 12/145 (8%)
 Frame = +2

Query: 84  GDVCPKPVFAFHHANFPQYVMDVLMDQHFTEPTPIQCQGFPLALSGRDMVGIAQTGSGKT 143
           GD  P  + +F      + + + ++   + +PTP+Q    P+ L  RD++  AQTGSGKT
Sbjct: 608 GDSPPPHINSFEECTLGEIIRNNIVLSKYNKPTPVQKFALPIVLGKRDLMACAQTGSGKT 787

Query: 144 LAYLLPAIVHI------------NHQPYLERGDGPICLVLAPTRELAQQVQQVADDYGKC 191
            A+LLP +  +            N      R   PI L+LAPTRELA Q+   A  +   
Sbjct: 788 AAFLLPILNQVYENGPTPEALQQNQSRGYRRKMYPIALILAPTRELASQIYDEARKFAYR 967

Query: 192 SRLKSTCIYGGAPKGPQIRDLERGV 216
           SRL+   +YGGA  G Q+RDL++G 
Sbjct: 968 SRLRPCVVYGGADIGAQMRDLDKGC 1042
>14337
          Length = 693

 Score = 91.3 bits (225), Expect = 1e-18,   Method: Compositional matrix adjust.
 Identities = 42/131 (32%), Positives = 70/131 (53%)
 Frame = +2

Query: 342 TIIFVETKXXXXXXXXXXXXXGWPAMCIHGDKSQPERDWVLNEFRSGKAPILIATDVASR 401
            ++FV++K                   IH DK Q ERD  +  F  G+  +L+ T++  R
Sbjct: 65  VLVFVQSKQRAKELYSEFMFDKHKVDAIHADKPQAERDATVRAFTEGRVWVLVCTELMGR 244

Query: 402 GLDVEDVKFVINYDYPNSSEDYVHRIGRTARSTNKGTAYTFFTPGNLKQARELIKVLEEA 461
           G+D + +  VINYD+P ++  Y+HRIGRT R+   G A TFFT  ++   R +  +++EA
Sbjct: 245 GIDFKGINLVINYDFPTNAVSYIHRIGRTGRAGVPGRAITFFTEQDVTHLRSIANIIKEA 424

Query: 462 NQAINPKLMQL 472
              +   +++L
Sbjct: 425 GCEVPEYMLRL 457
>08036
          Length = 1226

 Score = 60.1 bits (144), Expect(2) = 3e-18,   Method: Compositional matrix adjust.
 Identities = 40/178 (22%), Positives = 83/178 (46%)
 Frame = +1

Query: 220 IATPGRLIDFLESGKTNLRRCTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSAT 279
           + TP R++  L +G   L     LV+DEAD +   G E  ++K+++++    Q  + SAT
Sbjct: 4   VGTPSRILAHLRAGHLELHTVQMLVVDEADLVFSFGHEADMKKLMEELPRIYQAFLMSAT 183

Query: 280 WPKEVRQLAEDFLRDYTQINVGNLELSANHNILQIVDVCMESEKDHKLIQLMEEIMAEKE 339
             ++V+ L +  L +   + +   +L  +  + Q    C   +K   ++ +++  +    
Sbjct: 184 LSEDVKALKKMVLHNPVILKLKESQLPESTQLTQYHVKCEVDDKFTLMVAVLK--LGLVR 357

Query: 340 NKTIIFVETKXXXXXXXXXXXXXGWPAMCIHGDKSQPERDWVLNEFRSGKAPILIATD 397
            K+I+FV +              G PA  ++ +     R  ++++F  G   I+IA+D
Sbjct: 358 GKSILFVNSVDSCYKLKLFLEPFGIPACVLNSELPVKSRCHIVSQFNEGLYDIIIASD 531

 Score = 50.1 bits (118), Expect(2) = 3e-18,   Method: Compositional matrix adjust.
 Identities = 18/45 (40%), Positives = 32/45 (71%)
 Frame = +3

Query: 400 SRGLDVEDVKFVINYDYPNSSEDYVHRIGRTARSTNKGTAYTFFT 444
           +RG+D ++V  VIN+++P + + Y+HR+GRTAR   +G A +  +
Sbjct: 612 ARGIDFQNVSNVINFEFPKTVDAYIHRVGRTARGDKQGCALSLIS 746
>34295
          Length = 694

 Score = 86.7 bits (213), Expect = 3e-17,   Method: Compositional matrix adjust.
 Identities = 51/131 (38%), Positives = 71/131 (54%), Gaps = 1/131 (0%)
 Frame = -1

Query: 342 TIIFVETKXXXXXXXXXXXXXGWPAMCIHGDKSQPERDWVLNEFRSGKAPILIATDVASR 401
            +IF  TK                 +C+HG   Q ER   L+ F+S     LIATDVA+R
Sbjct: 535 VMIFTNTKKYCQLLSMTLTNMEIENVCLHGFMRQKERVSALSRFKSNHIRTLIATDVAAR 356

Query: 402 GLDVEDVKFVINYDYPNSSEDYVHRIGRTARSTNKGTAYTFFT-PGNLKQARELIKVLEE 460
           GLD+  V+ VIN+  P + ++Y+HR+GRTAR+  KG A + F  P +L    EL+  +EE
Sbjct: 355 GLDIPSVQLVINHMLPRTPKEYIHRVGRTARAGRKGVAISIFRFPRDL----ELLGAIEE 188

Query: 461 ANQAINPKLMQ 471
               IN KL +
Sbjct: 187 ---EINTKLTE 164
>19525
          Length = 585

 Score = 85.1 bits (209), Expect = 8e-17,   Method: Compositional matrix adjust.
 Identities = 54/138 (39%), Positives = 76/138 (55%), Gaps = 5/138 (3%)
 Frame = +2

Query: 169 LVLAPTRELAQQVQQVADDYGKCSRLKSTCIYGGAPKGPQIRDLERGVEIC----IATPG 224
           LVL PTRELA QV QV     + +++ S C+  G   G  I+  E  + +C    +ATPG
Sbjct: 23  LVLVPTRELAVQVYQVGQQISQYTKI-SICLAAG---GLDIKGQEAALRLCPDIVVATPG 190

Query: 225 RLIDFLESG-KTNLRRCTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKE 283
           RLID L +     +     LVLDEADRMLD  F  Q+ +I+      RQT+++SAT    
Sbjct: 191 RLIDHLHNAPNFTIAHVEILVLDEADRMLDEYFAAQMTEIIRMCNFQRQTMLFSATMSDA 370

Query: 284 VRQLAEDFLRDYTQINVG 301
           V+ LA   L++  ++ V 
Sbjct: 371 VQDLASVSLKEAVKVFVN 424
>17708
          Length = 882

 Score = 84.0 bits (206), Expect = 2e-16,   Method: Compositional matrix adjust.
 Identities = 42/102 (41%), Positives = 66/102 (64%)
 Frame = +1

Query: 130 RDMVGIAQTGSGKTLAYLLPAIVHINHQPYLERGDGPICLVLAPTRELAQQVQQVADDYG 189
           RD++G A+TGSGKTLA+L+PAI  +    ++ R +G  C++++PTREL+ Q   V  +  
Sbjct: 553 RDLMGAAKTGSGKTLAFLIPAIELMYKLKFMPR-NGTGCIIISPTRELSMQTFNVLTELL 729

Query: 190 KCSRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLE 231
           K        I GG  +  +++ L++GV I +ATPGRL+D L+
Sbjct: 730 KYHHHTFGLIMGGVNRHDEVKKLKKGVNIIVATPGRLLDHLQ 855
>19640
          Length = 456

 Score = 78.6 bits (192), Expect = 7e-15,   Method: Composition-based stats.
 Identities = 34/86 (39%), Positives = 52/86 (60%)
 Frame = -1

Query: 344 IFVETKXXXXXXXXXXXXXGWPAMCIHGDKSQPERDWVLNEFRSGKAPILIATDVASRGL 403
           IF  T+              +    +HGD  Q +R+ ++ +FRSG + +LI TD+ +RG+
Sbjct: 456 IFCNTRRKVDQLTQEMSSHNFTVSAMHGDMEQRDREVIMKQFRSGSSRVLITTDLLARGI 277

Query: 404 DVEDVKFVINYDYPNSSEDYVHRIGR 429
           DV+ V  VINYD P++ E+Y+HRIGR
Sbjct: 276 DVQQVSLVINYDLPSNRENYIHRIGR 199
>02498
          Length = 1955

 Score = 77.4 bits (189), Expect = 2e-14,   Method: Compositional matrix adjust.
 Identities = 64/208 (30%), Positives = 105/208 (50%), Gaps = 6/208 (2%)
 Frame = +1

Query: 91  VFAFHHANFPQYVMDVLMDQHFTEPTPIQCQGFPLALSG--RDMVGIAQTGSGKTLAYLL 148
           V +F   N    ++  + D  F  P+ IQ    P+ L+    +M+  +Q+G+GKT A++L
Sbjct: 130 VKSFEALNLKPQLLKGVYDMGFNAPSKIQETALPILLADPPVNMIAQSQSGTGKTAAFVL 309

Query: 149 PAIVHIN-HQPYLERGDGPICLVLAPTRELAQQVQQVADDYGKCSRLKSTCIYGGAPKGP 207
             +  ++  Q +      P CL LAPT ELA Q+ +V +   K S+  +      A +G 
Sbjct: 310 TMLSRVDISQTF------PQCLCLAPTYELALQIGEVIE---KMSKHMTGLEIRYAVRGE 462

Query: 208 QIRDLERGVE-ICIATPGRLIDFLESGKT-NLRRCTYLVLDEADRMLDM-GFEPQIRKIV 264
           ++   E   E I I TPG ++D+    K   L +    VLDEAD M+ M G + Q  +I 
Sbjct: 463 RVNRGEVLSEQIVIGTPGTVMDWSHRFKALPLEKLRVFVLDEADVMISMQGHQDQSTRIQ 642

Query: 265 DQIRPDRQTLMWSATWPKEVRQLAEDFL 292
            ++    Q L++SAT+ + V Q A+  +
Sbjct: 643 KRLSSGCQMLLFSATYDQVVMQFAQRII 726

 Score = 63.2 bits (152), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 31/75 (41%), Positives = 45/75 (60%), Gaps = 6/75 (8%)
 Frame = +3

Query: 371  GDKSQPERDWVLNEFRSGKAPILIATDVASRGLDVEDVKFVINYDYPNS------SEDYV 424
            G+ +  +R  ++  FR GK  +LI T+V++RG+DVE V  V+N+D P +       E Y+
Sbjct: 954  GELTIEQRAAIIKRFREGKEKVLITTNVSARGIDVEMVTVVVNFDLPVTQDWRPDCETYL 1133

Query: 425  HRIGRTARSTNKGTA 439
            HRIGRT R    G A
Sbjct: 1134 HRIGRTGRFGKNGIA 1178
>11160
          Length = 646

 Score = 69.7 bits (169), Expect(2) = 2e-14,   Method: Composition-based stats.
 Identities = 49/146 (33%), Positives = 74/146 (50%), Gaps = 9/146 (6%)
 Frame = -1

Query: 212 LERGVEICIATPGRLIDFL---ESG---KTNLRRCTYLVLDEADRMLDMGFEPQIRKIVD 265
           ++ G  I IATPGRL D     ESG     +++    LVLDEADR+LDMGFE  I  I+ 
Sbjct: 610 MKSGGSILIATPGRLDDLFSRKESGFNLAASVKALEVLVLDEADRLLDMGFEASINTILG 431

Query: 266 QIRPDRQTLMWSATWPKEVRQLAEDFLRDYTQINVGNLELSA---NHNILQIVDVCMESE 322
            +   R+T ++SAT   EV  L    LR+  ++ V   +L+          + +  M  E
Sbjct: 430 HLPKLRRTGLFSATQTDEVENLIRAGLRNPLRVTVKEKKLAGEADQRTPSTLSNYYMIVE 251

Query: 323 KDHKLIQLMEEIMAEKENKTIIFVET 348
            + K  QL++ +     +K ++F  T
Sbjct: 250 AEEKFSQLVKFLKTHHRDKLLLFFST 173

 Score = 27.7 bits (60), Expect(2) = 2e-14,   Method: Composition-based stats.
 Identities = 13/39 (33%), Positives = 22/39 (56%)
 Frame = -3

Query: 366 AMCIHGDKSQPERDWVLNEFRSGKAPILIATDVASRGLD 404
           A  +   + + E   V  +FRS  + +L+ TDV +RG+D
Sbjct: 119 AGVVDSQQDEAEEKPVFAKFRSITSGLLVCTDVMARGVD 3
>00617
          Length = 1505

 Score = 76.6 bits (187), Expect = 3e-14,   Method: Compositional matrix adjust.
 Identities = 40/96 (41%), Positives = 57/96 (59%)
 Frame = -3

Query: 364  WPAMCIHGDKSQPERDWVLNEFRSGKAPILIATDVASRGLDVEDVKFVINYDYPNSSEDY 423
            +    +H    Q  R   L+ F+S +  ILI+TDVASRGLD+  V  +IN++ PN   DY
Sbjct: 1482 FSCAVLHSMIPQRFRLSSLSRFKSNQTRILISTDVASRGLDIPTVDLIINHNIPNRPRDY 1303

Query: 424  VHRIGRTARSTNKGTAYTFFTPGNLKQARELIKVLE 459
            VHR+GRTAR+   G + +  T  ++K    LIK +E
Sbjct: 1302 VHRVGRTARAGRCGQSISLVTEFDIK----LIKSIE 1207
>12995
          Length = 1072

 Score = 75.5 bits (184), Expect = 6e-14,   Method: Compositional matrix adjust.
 Identities = 35/125 (28%), Positives = 67/125 (53%)
 Frame = +3

Query: 318 CMESEKDHKLIQLMEEIMAEKENKTIIFVETKXXXXXXXXXXXXXGWPAMCIHGDKSQPE 377
           C   +K+  L+ L+ ++++E +  T++FV TK             G     I+    Q  
Sbjct: 69  CRADDKEAMLLYLLRDVISEND-LTVVFVATKHHVEYLNTLLTKCGIACTYIYSSLDQTA 245

Query: 378 RDWVLNEFRSGKAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYVHRIGRTARSTNKG 437
           R   + +F   +  +++ TD+A+RG+D+  +  V+N+ +P  ++ +VHR+GR AR+   G
Sbjct: 246 RKIHVAKFTHKQVKVMLVTDLAARGIDIPQLDNVVNFHFPAKAKLFVHRVGRVARAGRSG 425

Query: 438 TAYTF 442
           TAY+ 
Sbjct: 426 TAYSL 440
>11624
          Length = 2257

 Score = 71.2 bits (173), Expect = 1e-12,   Method: Compositional matrix adjust.
 Identities = 35/104 (33%), Positives = 58/104 (55%), Gaps = 9/104 (8%)
 Frame = -1

Query: 378 RDWVLNEFRSGKAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYVHRIGRTARSTNKG 437
           R  +L +F  GK  +L+ +D  +RG+DV++VK+VI+YD P   + Y+HR+GRTAR+   G
Sbjct: 784 RKKILKQFSKGKIDLLVCSDAMARGMDVDNVKYVISYDNPPYIKTYIHRVGRTARAGRAG 605

Query: 438 TAYTFFTPGNLKQAREL---------IKVLEEANQAINPKLMQL 472
           TA +          +++         IK ++   QA+ P + Q 
Sbjct: 604 TAISLLEKKEFFHFKQMMREAGKWKKIKEMKLGRQALKPLVPQF 473

 Score = 65.9 bits (159), Expect = 5e-11,   Method: Compositional matrix adjust.
 Identities = 48/140 (34%), Positives = 72/140 (51%), Gaps = 12/140 (8%)
 Frame = -3

Query: 126  ALSGRDMVGIAQTGSGKTLAYLLPAIVHINHQ--PYLERGDGPICLVLAPTRELAQQVQQ 183
             L  RD+   A TGSGKTLAY LP I  +  +  P++        +++ P R+LA+QV Q
Sbjct: 1826 GLRPRDICVSAPTGSGKTLAYTLPIIQCLKQRMVPHVR------AVIVLPVRDLAEQVYQ 1665

Query: 184  VADDYGKCSRLKSTCIYGGAPKGPQIRDLERG---------VEICIATPGRLIDFLESGK 234
            V   Y   + LK   + G      +   L +          ++I +ATPGRL+D + S  
Sbjct: 1664 VFCHYCADTPLKVGIVVGKTVFNVEQDTLVKKRYGGVYHSVIDILVATPGRLVDHINSTP 1485

Query: 235  T-NLRRCTYLVLDEADRMLD 253
              +L    +LV+DEADRM++
Sbjct: 1484 GFDLSHLRFLVIDEADRMME 1425
>39583
          Length = 234

 Score = 68.6 bits (166), Expect = 7e-12,   Method: Composition-based stats.
 Identities = 30/57 (52%), Positives = 43/57 (75%)
 Frame = -3

Query: 377 ERDWVLNEFRSGKAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYVHRIGRTARS 433
           +R   L  F+ G+  +L+ATD+ASRGLD+E VK VIN+  P++ + YVHR+GRTAR+
Sbjct: 175 QRLEALKRFKEGEIDVLLATDLASRGLDIEGVKTVINFTMPSTLKHYVHRVGRTARA 5
>10649
          Length = 472

 Score = 62.4 bits (150), Expect = 5e-10,   Method: Compositional matrix adjust.
 Identities = 33/84 (39%), Positives = 40/84 (47%)
 Frame = +1

Query: 363 GWPAMCIHGDKSQPERDWVLNEFRSGKAPILIATDVASRGLDVEDVKFVINYDYPNSSED 422
           G   + +HG   Q  R  +  EF   +  ILI TD+A RGLD   V +VI  D P     
Sbjct: 64  GMSVLVLHGGIPQLRRLDIYREFCRKQHVILITTDLACRGLDFPAVNWVIQLDCPVDVNT 243

Query: 423 YVHRIGRTARSTNKGTAYTFFTPG 446
           Y+HR GRTAR    G A     P 
Sbjct: 244 YIHRAGRTARFECNGQALLVLLPS 315
>03381
          Length = 1206

 Score = 60.1 bits (144), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 28/73 (38%), Positives = 43/73 (58%)
 Frame = +3

Query: 403 LDVEDVKFVINYDYPNSSEDYVHRIGRTARSTNKGTAYTFFTPGNLKQARELIKVLEEAN 462
           LD+  ++ V+NYD     + + HR+GRT R+  KG+AYT  T  + + A  L++ LE AN
Sbjct: 3   LDIPHIRTVVNYDVARDIDTHTHRVGRTGRAGEKGSAYTLITDKDKEFAPLLVRNLEGAN 182

Query: 463 QAINPKLMQLVDH 475
           Q   P L+ L + 
Sbjct: 183 QTPPPALLDLANQ 221
>31899
          Length = 453

 Score = 57.0 bits (136), Expect = 3e-08,   Method: Composition-based stats.
 Identities = 39/124 (31%), Positives = 59/124 (47%), Gaps = 1/124 (0%)
 Frame = -1

Query: 82  RGGDVCPKPVFAFHHANFPQYVMDVLMDQHFTEPTPIQCQGFPLALSGRDMVGIAQTGSG 141
           R  DV       F      + V++ L +  F  P+PIQ +  PL   G D++  A++G+G
Sbjct: 375 RTNDVMTSESVDFASLLLSKPVLNGLKNAGFERPSPIQLKAIPLGRCGLDLIVQAKSGTG 196

Query: 142 KTLAYLLPAIVHINHQPYLERGDGPICLVLAPTRELAQQVQQVADDYGKC-SRLKSTCIY 200
           KT  + + A+  I       +      LVLAPTRE+A Q+ +V +  G   S L+     
Sbjct: 195 KTCVFSVVALEGIETTARSTQ-----VLVLAPTREIALQIWEVINSIGSAMSGLQCHTFI 31

Query: 201 GGAP 204
           GG P
Sbjct: 30  GGLP 19
>31220
          Length = 818

 Score = 53.5 bits (127), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 28/71 (39%), Positives = 37/71 (52%)
 Frame = +2

Query: 399 ASRGLDVEDVKFVINYDYPNSSEDYVHRIGRTARSTNKGTAYTFFTPGNLKQARELIKVL 458
           ASRG+D + V  VIN+D+P     Y+HR GRTAR  N G+  +F +   L          
Sbjct: 161 ASRGIDFQGVNNVINFDFPLDVTSYIHRAGRTARGNNTGSVLSFVSVKELP--------- 313

Query: 459 EEANQAINPKL 469
              NQA+  KL
Sbjct: 314 --INQAVEEKL 340
>19151
          Length = 625

 Score = 52.4 bits (124), Expect = 6e-07,   Method: Composition-based stats.
 Identities = 25/54 (46%), Positives = 32/54 (59%), Gaps = 6/54 (11%)
 Frame = -3

Query: 392 ILIATDVASRGLDVEDVKFVINYDYP------NSSEDYVHRIGRTARSTNKGTA 439
           +LI T+V SRG+D+E V  V+N+D P         E Y+HRIGRT R    G A
Sbjct: 620 VLITTNVLSRGIDIEQVTIVVNFDLPIDLRGNADCETYLHRIGRTGRFGKSGIA 459
>33083
          Length = 1931

 Score = 47.8 bits (112), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 21/49 (42%), Positives = 31/49 (63%), Gaps = 1/49 (2%)
 Frame = +1

Query: 401 RGLDVEDVKFVINYDYPNSSEDYVHRIGRTARST-NKGTAYTFFTPGNL 448
           RGLD+  V +++ YD P+ S++Y+HR+GRTAR   + G A     P  L
Sbjct: 1   RGLDIPQVDWIVQYDPPDESKEYIHRVGRTARGEGSSGKALLLLQPEEL 147
>11423
          Length = 1434

 Score = 43.1 bits (100), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 23/73 (31%), Positives = 37/73 (50%), Gaps = 9/73 (12%)
 Frame = -2

Query: 409  KFVINYDYPNSSEDYVHRIGRTARSTNKGTAYTFFTPGNLKQAREL---------IKVLE 459
            K+VI+YD P   + Y+HR+GRTAR+   GTA +          +++         IK ++
Sbjct: 1397 KYVISYDNPPYIKTYIHRVGRTARAGRAGTAISLLEKKEFFHFKQMMREAGKWKKIKEMK 1218

Query: 460  EANQAINPKLMQL 472
               QA+ P + Q 
Sbjct: 1217 LGRQALKPLVPQF 1179
>06438
          Length = 989

 Score = 43.1 bits (100), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 21/52 (40%), Positives = 25/52 (48%)
 Frame = +1

Query: 394 IATDVASRGLDVEDVKFVINYDYPNSSEDYVHRIGRTARSTNKGTAYTFFTP 445
           +   +A RGLD   V +VI  D P     Y+HR GRTAR    G A     P
Sbjct: 25  LTVTLACRGLDFPAVNWVIQLDCPVDVNTYIHRAGRTARFECNGQALLVLLP 180
>01821
          Length = 910

 Score = 38.9 bits (89), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 21/58 (36%), Positives = 29/58 (50%)
 Frame = +1

Query: 393 LIATDVASRGLDVEDVKFVINYDYPNSSEDYVHRIGRTARSTNKGTAYTFFTPGNLKQ 450
           L++T V   GLD+ DV  ++ YD   S    V R+GRT R   +G      T G  +Q
Sbjct: 13  LVSTCVGEEGLDIGDVDLIVCYDAHKSPVRLVQRMGRTGRK-RQGRIVMLMTEGKEEQ 183
>27757
          Length = 458

 Score = 30.8 bits (68), Expect = 1.7,   Method: Composition-based stats.
 Identities = 14/53 (26%), Positives = 28/53 (52%)
 Frame = -2

Query: 414 YDYPNSSEDYVHRIGRTARSTNKGTAYTFFTPGNLKQARELIKVLEEANQAIN 466
           +D+P   +   H +G ++    K + Y+   P ++K+ARE   +L  AN  ++
Sbjct: 307 HDHPGRLQTAEHHLGSSSEEICKKSWYSMLHPEDIKEAREKHVLLLRANHELS 149
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|52317148|ref|NP_067467.2| adaptor-related protein
complex 3, beta 2 subunit [Mus musculus]
         (1082 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

31995                                                                 387   e-129
06708                                                                 165   1e-40
>31995
          Length = 1263

 Score =  387 bits (994), Expect(2) = e-129,   Method: Compositional matrix adjust.
 Identities = 192/263 (73%), Positives = 224/263 (85%)
 Frame = -2

Query: 344  LVRLLRSHSEVQYVVLQNVATMSIKRRGMFEPYLKSFYIRSTDPTQIKILKLEVLTNLAN 403
            L+RLLRSH E+QYVVL +VATM+ KR+GMFEPYLKSFY+RS+DP  IK+LKLE+LTNLA 
Sbjct: 1262 LIRLLRSHQEIQYVVLSDVATMTTKRKGMFEPYLKSFYVRSSDPLHIKLLKLEILTNLAT 1083

Query: 404  ETNIPTVLREFQTYIRSMDKDFVAATIQAIGRCATNIGRVRDTCLNGLVQLLSNRDELVV 463
            ETNI T+LREFQTY+ S DK+F AATIQAIGRCA++I  V DTCLNGLV L+SNRBE VV
Sbjct: 1082 ETNISTILREFQTYVTSSDKEFAAATIQAIGRCASSICEVTDTCLNGLVHLMSNRBEAVV 903

Query: 464  AESVVVIKKLLQMQPAQHGEIIKHLAKLTDNIQVPMARASILWLIGEYCEHVPKIAPDVL 523
            AESVVVIKKLLQM+P +H  II H+A++ D I VPMARASILWLIGEY E VPKIAPDVL
Sbjct: 902  AESVVVIKKLLQMRPNEHKGIICHMARMVDKITVPMARASILWLIGEYSERVPKIAPDVL 723

Query: 524  RKMAKSFTAEEDIVKLQVINLAAKLYLTNSKQTKLLTQYVLSLAKYDQNYDIRDRARFTR 583
            RK+AKSFT+EEDIVKLQV+NLA KL +TN KQTKLL QYVL+LAKYDQNYDIRDR+RF R
Sbjct: 722  RKLAKSFTSEEDIVKLQVLNLATKLCITNPKQTKLLCQYVLNLAKYDQNYDIRDRSRFLR 543

Query: 584  QLIVPSEQGGALSRHAKKLFLAP 606
            Q+++P E G   S++AK+    P
Sbjct: 542  QMVLPGENGCVFSKYAKRCSWPP 474

 Score = 96.3 bits (238), Expect(2) = e-129,   Method: Compositional matrix adjust.
 Identities = 46/73 (63%), Positives = 57/73 (78%), Gaps = 3/73 (4%)
 Frame = -3

Query: 609 APILESSFKDRDHFQLGSLSHLLNAKATGYQELPDWPEEAPDPSVRNVEVPE-WTKCSNR 667
           AP+L S FKDRD FQLG+LSH+LN + TGYQELP+WPE APDPSVRNVE+P  WT+  ++
Sbjct: 469 APVLASKFKDRDFFQLGTLSHVLNMRTTGYQELPEWPEAAPDPSVRNVELPPVWTEKPSK 290

Query: 668 --EKRKEKEKPFY 678
              K+K+  K FY
Sbjct: 289 VSTKKKQDLKSFY 251
>06708
          Length = 980

 Score =  165 bits (417), Expect = 1e-40,   Method: Compositional matrix adjust.
 Identities = 89/221 (40%), Positives = 124/221 (56%)
 Frame = +1

Query: 860  QELLHRVAGEGLSVDYAFSRQPFSGDPHMVSLHIYFSNNSETPIKGLHVGTPKLPAGISI 919
             ELL+R++G GLS+ Y F+R      P MVS+     NN +TP+  + +G  K+  G+ +
Sbjct: 199  HELLNRISGSGLSISYKFTRTISVFSPKMVSIEWTLINNGDTPLTSIKLGDTKVQPGMEV 378

Query: 920  QEFPEIESLAPGESTTTVMGINFCDSTQAANFQLCTQTRQFYVSIQPPVGELMAPVFMSE 979
            Q FPEI SL  G ST+ +MGINF D+TQ A   +C    +F VSI  PVGEL+ P  MSE
Sbjct: 379  QPFPEIASLGVGASTSVLMGINFNDTTQPAAMDVCVGEHKFKVSITAPVGELLQPHTMSE 558

Query: 980  NEFKKEQGKLTGMNEITEKLTLPDTCRSDHMVVQKVTATANLGRVPCGTSDEYRFAGRXX 1039
             +F  +QGKL GMNE +  + + +   S   +   V    NL +VP    + +RFA +  
Sbjct: 559  GDFTLQQGKLGGMNENSASVAIDEETGSAKAICTSVLTAGNLLQVPSSDENIFRFAAKTL 738

Query: 1040 XXXXXXXXXXDARAAGAAQLTVNSEKMVIGTMLVKDVIQAL 1080
                             A++TVNSEKMVI  ML+KDV +A+
Sbjct: 739  ASGTLVLVTVKTSEK-KAKVTVNSEKMVICAMLLKDVQKAM 858
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|7710042|ref|NP_057930.1| IQ motif containing GTPase
activating protein 1 [Mus musculus]
         (1657 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

13259                                                                 458   e-129
17703                                                                 150   3e-39
30880                                                                 141   2e-33
>13259
          Length = 1751

 Score =  458 bits (1179), Expect = e-129,   Method: Compositional matrix adjust.
 Identities = 251/477 (52%), Positives = 323/477 (67%), Gaps = 48/477 (10%)
 Frame = +2

Query: 14  RPHYGSVLDNERLTAEEMDERRRQNVAYEYLCHLEEAKRWMEACLGEDLPPTTELEEGLR 73
           +PHY   L++ RLTA+EMDE+R++N+AYEYLCHLEEAK W++AC+ EDLPPTTELEEGLR
Sbjct: 284 KPHY-RTLEDARLTADEMDEQRKRNIAYEYLCHLEEAKVWIQACINEDLPPTTELEEGLR 460

Query: 74  NGVYLAKLGNFFSPKVVSLKKIYDREQTRYKATGLHFRHTDNVIQWLNAMDEIGLPKIFY 133
           NGV+LAKLG+FF+  VVSLKKIYD++QTRYK+ GLHFRHTDN+  WL AM+E+GLP IFY
Sbjct: 461 NGVFLAKLGHFFAAXVVSLKKIYDKDQTRYKSRGLHFRHTDNINHWLRAMEEVGLPTIFY 640

Query: 134 PETTDIYDRKNMPRCIYCIHALSLYLFKLGLAPQIQDLYGKVDFTEEEINNMKIELEKYG 193
           PETTDIYDRKN+PR +YC+HALSLYLFKLGLAPQIQDLYGK++FTEEEI+ M+ EL+KYG
Sbjct: 641 PETTDIYDRKNIPRAVYCVHALSLYLFKLGLAPQIQDLYGKINFTEEEISAMRSELDKYG 820

Query: 194 IQMPAFSKIGGILANELSVDEAALHAAVIAINEAIDRRVAADTFTALKNPNAMLVNLEEG 253
           IQMPAFSKIGGILANE++VD+AALHAA+IAINEA+D++VAADT TA++N +AMLVNL+  
Sbjct: 821 IQMPAFSKIGGILANEMTVDDAALHAAIIAINEAVDQQVAADTMTAMQNASAMLVNLDPD 1000

Query: 254 LAPTYQDVLYQAKQDKMTNAKNRTE----------------------------------- 278
           +A  YQD LY AK  K   A+N+ E                                   
Sbjct: 1001VAQHYQDQLYSAKHTKAEVARNKLEEIKSLAQRLQNPSLILYGTHEMTQGTRGGDGMPVK 1180

Query: 279 ------NSDRER----DVYEELLTQAEIQGNVNKVNTSSALANISLALEQGCAVTXXXXX 328
                 + D ER    DVY+ELLTQAEIQG +NKVN S AL  ++ AL +G         
Sbjct: 1181XNGQPGSIDPERSYDHDVYDELLTQAEIQGXINKVNISVALDRVNDALLKGDLSLLLAAL 1360

Query: 329 XXXXXXXRGLQTQNSDWYMKQLQS--DLQQKRQSGQTDPLQKEEVQAGVDAAN-SAAQQY 385
                  R +   N+++Y  +L+   +L++   +G+   L KEE+Q  ++ AN  A+ QY
Sbjct: 1361RVPSLGLRDVTDDNAEYYAAKLREAHELKKNNNNGEEXQLDKEELQQAINQANLEASAQY 1540

Query: 386 QRRLXXXXXXXXXXQKGIAEKTVLELMNPEAQLPQVYPFAADLYQKELATLQQQSPE 442
           ++              G A++ +    N  A  PQVY FA  LY +ELA ++ +  E
Sbjct: 1541EKE-QAVKAVNAAIDSGEADQVLKAFQNSAALFPQVYDFAGXLYLEELACIKAEKQE 1708

 Score = 45.8 bits (107), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 44/161 (27%), Positives = 73/161 (45%)
 Frame = +2

Query: 515  FITWNDIQACVDHVNLVVHEEHERILAIGLINEALDEGDAQKTLQALQIPAAKLEGVLAE 574
             +T  +IQ  ++ VN+ V        A+  +N+AL +GD    L AL++P+  L  V  +
Sbjct: 1244 LLTQAEIQGXINKVNISV--------ALDRVNDALLKGDLSLLLAALRVPSLGLRDVTDD 1399

Query: 575  VAQHYQDTLIRAKREKAQETQDESAVLWLDEIQGGIWQSNKDTQEAQRFALGISAINEAV 634
             A++Y   L  A   K      E   L  +E+Q  I Q+N +          + A+N A+
Sbjct: 1400 NAEYYAAKLREAHELKKNNNNGEEXQLDKEELQQAINQANLEASAQYEKEQAVKAVNAAI 1579

Query: 635  DSGDVGRTLSALRSPDVGLYGVIPECGETYQSDLAEAKKKR 675
            DSG+  + L A ++       V    G  Y  +LA  K ++
Sbjct: 1580 DSGEADQVLKAFQNSAALFPQVYDFAGXLYLEELACIKAEK 1702

 Score = 39.7 bits (91), Expect = 0.009,   Method: Compositional matrix adjust.
 Identities = 53/195 (27%), Positives = 79/195 (40%), Gaps = 56/195 (28%)
 Frame = +2

Query: 546  NEALDEGDAQKTLQALQIPAAKLEGVLAEVAQHYQDTLIRAKREK--------------A 591
            NEA+D+  A  T+ A+Q  +A L  +  +VAQHYQD L  AK  K              A
Sbjct: 914  NEAVDQQVAADTMTAMQNASAMLVNLDPDVAQHYQDQLYSAKHTKAEVARNKLEEIKSLA 1093

Query: 592  QETQDESAVLW-------------------------LD-----------------EIQGG 609
            Q  Q+ S +L+                         +D                 EIQG 
Sbjct: 1094 QRLQNPSLILYGTHEMTQGTRGGDGMPVKXNGQPGSIDPERSYDHDVYDELLTQAEIQGX 1273

Query: 610  IWQSNKDTQEAQRFALGISAINEAVDSGDVGRTLSALRSPDVGLYGVIPECGETYQSDLA 669
            I + N         ++ +  +N+A+  GD+   L+ALR P +GL  V  +  E Y + L 
Sbjct: 1274 INKVN--------ISVALDRVNDALLKGDLSLLLAALRVPSLGLRDVTDDNAEYYAAKLR 1429

Query: 670  EAKKKRLAAGDNNSK 684
            EA +  L   +NN +
Sbjct: 1430 EAHE--LKKNNNNGE 1468
>17703
          Length = 542

 Score =  150 bits (378), Expect(2) = 3e-39,   Method: Compositional matrix adjust.
 Identities = 81/161 (50%), Positives = 102/161 (63%), Gaps = 5/161 (3%)
 Frame = +3

Query: 1481 LINDIAKDIXXXXXXXXXXKAELVKLQQTYSALNSKATFYGEQVDYYKSYIKTCLDNLAS 1540
            LIN I +DI          K EL++++   ++LN K +FY  Q+D+Y  Y+KTCLDNL  
Sbjct: 3    LINAIVQDIRNQRRYRNNRKQELLRVRNXLNSLNEKRSFYESQIDFYNQYVKTCLDNLQH 182

Query: 1541 KGKVSKKPREM-----XXXXXXXXXXXYTAARLHEKGVLLEIEDLQANQFKNVIFEIGPT 1595
            K   SKKP++                 Y AA+LHEKGV+LEIE L  NQFKNV+FEI  T
Sbjct: 183  K---SKKPKKTGFFRRQGKQNATKSVQYNAAQLHEKGVVLEIESLPQNQFKNVLFEIAGT 353

Query: 1596 EEVGDFEVKAKFMGVQMETFMLHYQDLLQLQYEGVAVMKLF 1636
            E+ G F+V AKFMGV M+   L +QDLLQLQYEGVAVMK+ 
Sbjct: 354  EDPGVFDVSAKFMGVAMDKVELVFQDLLQLQYEGVAVMKML 476

 Score = 32.3 bits (72), Expect(2) = 3e-39,   Method: Composition-based stats.
 Identities = 15/16 (93%), Positives = 16/16 (100%)
 Frame = +2

Query: 1637 DRAKVNVNLLIFLLNK 1652
            +RAKVNVNLLIFLLNK
Sbjct: 476  NRAKVNVNLLIFLLNK 523
>30880
          Length = 671

 Score =  141 bits (356), Expect = 2e-33,   Method: Compositional matrix adjust.
 Identities = 78/204 (38%), Positives = 122/204 (59%)
 Frame = +3

Query: 505 KAQAHAENNAFITWNDIQACVDHVNLVVHEEHERILAIGLINEALDEGDAQKTLQALQIP 564
           K  A    N  +T  DI   ++ V+  V EE ERI AI  INEA+D+GD  +TL +LQ+P
Sbjct: 63  KLSARRAQNPLLTHADIVDTIETVHQKVQEEQERIKAIESINEAIDKGDESETLASLQMP 242

Query: 565 AAKLEGVLAEVAQHYQDTLIRAKREKAQETQDESAVLWLDEIQGGIWQSNKDTQEAQRFA 624
           +AKL  +    A HYQ  L + K  KA++TQDE AVLWL+EIQ  +  +N++ +E  + +
Sbjct: 243 SAKLSNIDPLQAVHYQVLLAKEKDRKAEKTQDEGAVLWLEEIQSTVDHANRNAEEGLKMS 422

Query: 625 LGISAINEAVDSGDVGRTLSALRSPDVGLYGVIPECGETYQSDLAEAKKKRLAAGDNNSK 684
            GI A+NEA+ + D    ++ L + + G + V  ECG TY   L + +++++ +G++ S 
Sbjct: 423 RGIQAVNEALATDDTDSLVAGL-TGEAGFHSVKTECGATYAEKLKQLQQEKMESGESGSG 599

Query: 685 WVKHWVKGGYHYYHNLETQAGGWA 708
           W+ + V  G  +++N  TQ   WA
Sbjct: 600 WMMNRVADGSKFFYNAHTQQYAWA 671

 Score = 37.4 bits (85), Expect = 0.054,   Method: Compositional matrix adjust.
 Identities = 40/152 (26%), Positives = 62/152 (40%), Gaps = 3/152 (1%)
 Frame = +3

Query: 455 EMLSSVALINRALESGDMTTVWKQLSSSVTGLTNIEEENCQRYLDELMK---LKAQAHAE 511
           E + ++  IN A++ GD +     L      L+NI+      Y   L K    KA+   +
Sbjct: 159 ERIKAIESINEAIDKGDESETLASLQMPSAKLSNIDPLQAVHYQVLLAKEKDRKAEKTQD 338

Query: 512 NNAFITWNDIQACVDHVNLVVHEEHERILAIGLINEALDEGDAQKTLQALQIPAAKLEGV 571
             A +   +IQ+ VDH N    E  +    I  +NEAL   D    +  L    A    V
Sbjct: 339 EGAVLWLEEIQSTVDHANRNAEEGLKMSRGIQAVNEALATDDTDSLVAGL-TGEAGFHSV 515

Query: 572 LAEVAQHYQDTLIRAKREKAQETQDESAVLWL 603
             E    Y + L + ++EK +    ES   W+
Sbjct: 516 KTECGATYAEKLKQLQQEKME--SGESGSGWM 605

 Score = 33.1 bits (74), Expect = 1.0,   Method: Compositional matrix adjust.
 Identities = 19/50 (38%), Positives = 31/50 (62%)
 Frame = +3

Query: 220 AVIAINEAIDRRVAADTFTALKNPNAMLVNLEEGLAPTYQDVLYQAKQDK 269
           A+ +INEAID+   ++T  +L+ P+A L N++   A  YQ +L + K  K
Sbjct: 171 AIESINEAIDKGDESETLASLQMPSAKLSNIDPLQAVHYQVLLAKEKDRK 320
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|110625998|ref|NP_080676.3| DnaJ (Hsp40) homolog,
subfamily B, member 11 [Mus musculus]
         (358 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

14550                                                                 354   e-128
38321                                                                  80   1e-15
20488                                                                  76   3e-14
10680                                                                  74   1e-13
02324                                                                  72   4e-13
26984                                                                  68   5e-12
07620                                                                  48   1e-11
13998                                                                  64   6e-11
02088                                                                  64   9e-11
22505                                                                  38   7e-08
12040                                                                  50   1e-06
15360                                                                  37   0.013
33510                                                                  37   0.016
18150                                                                  36   0.031
13422                                                                  35   0.035
19018                                                                  34   0.10 
20155                                                                  29   2.6  
18599                                                                  28   6.3  
>14550
          Length = 1395

 Score =  354 bits (908), Expect(2) = e-128,   Method: Compositional matrix adjust.
 Identities = 164/234 (70%), Positives = 198/234 (84%)
 Frame = -2

Query: 124 QDRNIPRGSDIIVDLEVTLEEVYAGNFVEVVRNKPVARQAPGKRKCNCRQEMRTTQLGPG 183
           +DR +PRG D+++DL+VTLEE+Y+G+FVEV+R KPV++ A GKRKCNCR E  T QLGPG
Sbjct: 836 RDREVPRGGDVVMDLDVTLEELYSGDFVEVLRYKPVSKPAKGKRKCNCRMETVTQQLGPG 657

Query: 184 RFQMTQEVVCDECPNVKLVNEERTLEVEIEPGVRDGMEYPFIGEGEPHVDGEPGDLRFRI 243
           RFQM+Q+ VCDECPN+K V EE+ LEVEIEPG+RDG EYPF+ EGEPH+DGEPGDLRF I
Sbjct: 656 RFQMSQQQVCDECPNIKFVPEEKVLEVEIEPGMRDGQEYPFVAEGEPHMDGEPGDLRFII 477

Query: 244 KVVKHRIFERRGDDLYTNVTVSLVEALVGFEMDITHLDGHKVHISRDKITRPGAKLWKKG 303
           + VKH  FER+GDDLYTNVTVSL +AL+GFEMDI HLDGHKVH+ RDKIT PGA++ K  
Sbjct: 476 RQVKHARFERKGDDLYTNVTVSLQDALIGFEMDIVHLDGHKVHVIRDKITWPGARMRKSN 297

Query: 304 EGLPNFDNNNIKGSLIITFDVDFPKEQLTEEAKEGIKQLLKQGPVQKVYNGLQG 357
           EG+PN++NNN+KGSL ITFD+DFPK  L+EE KEG+K +LKQ   Q VYNGL G
Sbjct: 296 EGMPNYENNNVKGSLFITFDIDFPKGTLSEEDKEGLKAILKQDAKQMVYNGL*G 135

 Score =  123 bits (308), Expect(2) = e-128,   Method: Compositional matrix adjust.
 Identities = 61/91 (67%), Positives = 72/91 (79%), Gaps = 3/91 (3%)
 Frame = -1

Query: 10   CLL---LLYLIGTVIAGRDFYKILGVPRSASIKDIKKAYRKLALQLHPDRNPDDPQAQEK 66
            C L   LL L   V+ GRDFYKILGV +SA  K IK+AYRK+A +LHPD+N DDP+A+++
Sbjct: 1188 CFLAVNLLLLFVQVLGGRDFYKILGVSKSADTKQIKRAYRKIAKELHPDKNRDDPEAEQR 1009

Query: 67   FQDLGAAYEVLSDSEKRKQYDTYGEEGLKDG 97
            FQDLGAAYEVLSD EKRK YD +GEEGLK G
Sbjct: 1008 FQDLGAAYEVLSDEEKRKVYDRHGEEGLKQG 916

 Score = 80.9 bits (198), Expect = 7e-16,   Method: Compositional matrix adjust.
 Identities = 37/59 (62%), Positives = 46/59 (77%)
 Frame = -1

Query: 299  LWKKGEGLPNFDNNNIKGSLIITFDVDFPKEQLTEEAKEGIKQLLKQGPVQKVYNGLQG 357
            + K  EG+PN++NNN+KGSL ITFD+DFPK  L+EE KEG+K +LKQ   Q VYNGL G
Sbjct: 1395 MRKSNEGMPNYENNNVKGSLFITFDIDFPKGTLSEEDKEGLKAILKQDAKQMVYNGL*G 1219
>38321
          Length = 1059

 Score = 80.5 bits (197), Expect = 1e-15,   Method: Compositional matrix adjust.
 Identities = 37/59 (62%), Positives = 46/59 (77%)
 Frame = -1

Query: 299  LWKKGEGLPNFDNNNIKGSLIITFDVDFPKEQLTEEAKEGIKQLLKQGPVQKVYNGLQG 357
            + K  EG+PN++NNN+KGSL ITFD+DFPK  L+EE KEG+K +LKQ   Q VYNGL G
Sbjct: 1059 MRKSNEGMPNYENNNVKGSLFITFDIDFPKGTLSEEDKEGLKAILKQDAKQMVYNGL*G 883
>20488
          Length = 3281

 Score = 75.9 bits (185), Expect = 3e-14,   Method: Compositional matrix adjust.
 Identities = 48/139 (34%), Positives = 71/139 (51%)
 Frame = -2

Query: 205  ERTLEVEIEPGVRDGMEYPFIGEGEPHVDGEPGDLRFRIKVVKHRIFERRGDDLYTNVTV 264
            ++ L + ++ G + G +  F  EG+   +  P D+ F +K   H  F R G +L     V
Sbjct: 1588 DKILTITVKKGWKPGTKITFPKEGDQGPNNVPADIVFIVKDKPHPRFRREGLNLIHTANV 1409

Query: 265  SLVEALVGFEMDITHLDGHKVHISRDKITRPGAKLWKKGEGLPNFDNNNIKGSLIITFDV 324
             L  AL G  +DI  LD   +HI  + I +PG K    GEG+P   +   KG LII F++
Sbjct: 1408 LLGRALTGTTVDIHTLDDRTLHIPINDIVKPGYKKIVPGEGMPMSSDPTZKGDLIIEFNI 1229

Query: 325  DFPKEQLTEEAKEGIKQLL 343
            +FP   LT E K+ I+  L
Sbjct: 1228 EFP-TSLTPERKDLIRTAL 1175
>10680
          Length = 1093

 Score = 73.6 bits (179), Expect = 1e-13,   Method: Compositional matrix adjust.
 Identities = 48/139 (34%), Positives = 71/139 (51%)
 Frame = -3

Query: 205 ERTLEVEIEPGVRDGMEYPFIGEGEPHVDGEPGDLRFRIKVVKHRIFERRGDDLYTNVTV 264
           ++ L + ++ G + G +  F  EG+   +  P D+ F +K   H  F R G +L     V
Sbjct: 731 DKILTITVKKGWKPGTKITFPKEGDQGPNNVPADIVFIVKDKPHPRFRREGLNLIHTANV 552

Query: 265 SLVEALVGFEMDITHLDGHKVHISRDKITRPGAKLWKKGEGLPNFDNNNIKGSLIITFDV 324
            L  AL G  +DI  LD   +HI  + I +PG K    GEG+P   +   KG LII F++
Sbjct: 551 LLGRALTGTTVDIHTLDDRTLHIPINDIVKPGYKKIVPGEGMPMSSDPTQKGDLIIEFNI 372

Query: 325 DFPKEQLTEEAKEGIKQLL 343
           +FP   LT E K+ I+  L
Sbjct: 371 EFP-TSLTPERKDLIRTAL 318
>02324
          Length = 2058

 Score = 71.6 bits (174), Expect = 4e-13,   Method: Compositional matrix adjust.
 Identities = 36/72 (50%), Positives = 51/72 (70%), Gaps = 1/72 (1%)
 Frame = +2

Query: 27  YKILGVPRSASIKDIKKAYRKLALQLHPDRNPDD-PQAQEKFQDLGAAYEVLSDSEKRKQ 85
           Y++LGV RSA   D+KKAYRKLAL+ HPD+NPD   +A  +F+ +  AYE+L+D ++R  
Sbjct: 110 YEVLGVERSADNDDLKKAYRKLALKFHPDKNPDSVEEATAQFRLVQQAYEILTDPQERSW 289

Query: 86  YDTYGEEGLKDG 97
           YD + E  L+ G
Sbjct: 290 YDRHREAILRGG 325
>26984
          Length = 1107

 Score = 68.2 bits (165), Expect = 5e-12,   Method: Compositional matrix adjust.
 Identities = 33/67 (49%), Positives = 49/67 (73%)
 Frame = -2

Query: 23  GRDFYKILGVPRSASIKDIKKAYRKLALQLHPDRNPDDPQAQEKFQDLGAAYEVLSDSEK 82
           G+D Y ILG+   AS +DIK+ YR+ A+ +HPD+N  +P A+E F+ LG A+E++ D  K
Sbjct: 521 GKDPYSILGLRADASDEDIKRYYRRQAVLVHPDKN-QEPGAEEAFKILGHAFEMIGDPTK 345

Query: 83  RKQYDTY 89
           RK+YDT+
Sbjct: 344 RKEYDTH 324
>07620
          Length = 1775

 Score = 47.8 bits (112), Expect(2) = 1e-11,   Method: Compositional matrix adjust.
 Identities = 19/41 (46%), Positives = 30/41 (73%)
 Frame = +1

Query: 17  IGTVIAGRDFYKILGVPRSASIKDIKKAYRKLALQLHPDRN 57
           +  + A +D+Y++L V +  +  D+KKAYRKLALQ+HPD+ 
Sbjct: 76  VKRIKACKDYYEVLDVKKDCTESDMKKAYRKLALQMHPDKT 198

 Score = 38.9 bits (89), Expect(2) = 1e-11,   Method: Compositional matrix adjust.
 Identities = 17/32 (53%), Positives = 23/32 (71%)
 Frame = +3

Query: 61  PQAQEKFQDLGAAYEVLSDSEKRKQYDTYGEE 92
           P A + F+ +G AY VLSD +KR++YD YG E
Sbjct: 204 PGATDAFKKIGNAYSVLSDPDKRRKYDVYGPE 299
>13998
          Length = 1075

 Score = 64.3 bits (155), Expect = 6e-11,   Method: Compositional matrix adjust.
 Identities = 34/70 (48%), Positives = 50/70 (71%), Gaps = 5/70 (7%)
 Frame = +1

Query: 24  RDFYKILGVPRSASIKDIKKAYRKLALQLHPDRNPD---DPQAQE--KFQDLGAAYEVLS 78
           +D+YKILG+ R+A+  +IKKAYRK AL  HPDR+ +   D +  E  KF+++G AY +LS
Sbjct: 202 KDYYKILGISRNATEDEIKKAYRKKALVHHPDRHANSSADVRKDEELKFKEVGEAYAILS 381

Query: 79  DSEKRKQYDT 88
           D  K+ +YD+
Sbjct: 382 DGAKKTRYDS 411
>02088
          Length = 1062

 Score = 63.9 bits (154), Expect = 9e-11,   Method: Compositional matrix adjust.
 Identities = 34/86 (39%), Positives = 50/86 (58%), Gaps = 2/86 (2%)
 Frame = +3

Query: 13  LLYLIGTVIAGRDFYKILGVPRSASIKDIKKAYRKLALQLHPDR--NPDDPQAQEKFQDL 70
           LL     +    D Y+++G+ R A+ +++KK Y K++L +HPD+    +   A  KFQ L
Sbjct: 72  LLQSCEELFETTDLYEVIGIRREATPQEVKKGYHKVSLAVHPDQVSAAEKETATRKFQTL 251

Query: 71  GAAYEVLSDSEKRKQYDTYGEEGLKD 96
           G  Y VLSD +KR  YD  GE G +D
Sbjct: 252 GKVYTVLSDKDKRAXYDETGEVGEED 329
>22505
          Length = 784

 Score = 38.1 bits (87), Expect(2) = 7e-08,   Method: Compositional matrix adjust.
 Identities = 20/37 (54%), Positives = 23/37 (62%)
 Frame = -1

Query: 21  IAGRDFYKILGVPRSASIKDIKKAYRKLALQLHPDRN 57
           I   D Y ILGV   A+ K I KAYRK AL+ HPD+ 
Sbjct: 664 IMKMDLYGILGVGPEANEKQIVKAYRKKALKCHPDKT 554

 Score = 35.8 bits (81), Expect(2) = 7e-08,   Method: Compositional matrix adjust.
 Identities = 15/33 (45%), Positives = 21/33 (63%)
 Frame = -3

Query: 56  RNPDDPQAQEKFQDLGAAYEVLSDSEKRKQYDT 88
           +NPD+P+A E F +L  A EVL+D   +  YD 
Sbjct: 560 QNPDNPKAAELFHELSKALEVLTDPSAKAAYDN 462
>12040
          Length = 1151

 Score = 50.4 bits (119), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 34/107 (31%), Positives = 52/107 (48%), Gaps = 6/107 (5%)
 Frame = -2

Query: 247  KHRIFERRGDDLYTNVTVSLVEALVGFEMDITHLDGHKVHISRDKITRPGAKLWKKG--- 303
            +H  F   G DL   + + LVEAL GF+  +  +D   + ++    T+PG  +  +    
Sbjct: 1123 EHSTFVHAGTDLMMKMPLQLVEALCGFQRIVKTMDDRDLLVA----TQPGEVIRHEMTKC 956

Query: 304  ---EGLPNFDNNNIKGSLIITFDVDFPKEQLTEEAKEGIKQLLKQGP 347
               EG+P F N   KG+LII F+V FP + +       +KQ L   P
Sbjct: 955  IAEEGMPIFKNPMEKGTLIIQFEVIFP-DVINPSVIPTLKQCLPPAP 818
>15360
          Length = 502

 Score = 37.0 bits (84), Expect = 0.013,   Method: Compositional matrix adjust.
 Identities = 14/52 (26%), Positives = 33/52 (63%)
 Frame = +1

Query: 27  YKILGVPRSASIKDIKKAYRKLALQLHPDRNPDDPQAQEKFQDLGAAYEVLS 78
           + +L +P  +  + +K  Y++LAL+ HP+++ +  +A ++F  +  AY +L+
Sbjct: 61  FNLLDIPAGSDQESLKTKYKQLALKWHPEKHKNAAEAVKQFIQVTQAYRLLA 216
>33510
          Length = 501

 Score = 36.6 bits (83), Expect = 0.016,   Method: Compositional matrix adjust.
 Identities = 24/78 (30%), Positives = 34/78 (43%), Gaps = 3/78 (3%)
 Frame = +3

Query: 12  LLLYLIGTVIAGRDFYKILGVPRSASIKDIKKAYRKLALQLHPDRNPDDPQ---AQEKFQ 68
           LL  L   +      +K  G+    S   +KK YRK  L +HPD+  DDP    A+  F 
Sbjct: 219 LLCSLDKVLWDSESRWKPCGMHDLVSADQVKKVYRKAVLSVHPDKLHDDPHEALAKLIFM 398

Query: 69  DLGAAYEVLSDSEKRKQY 86
           +L  A+    D   +  Y
Sbjct: 399 ELNDAWAKFEDEGMKSLY 452
>18150
          Length = 768

 Score = 35.8 bits (81), Expect = 0.031,   Method: Compositional matrix adjust.
 Identities = 15/23 (65%), Positives = 19/23 (82%)
 Frame = +2

Query: 73  AYEVLSDSEKRKQYDTYGEEGLK 95
           A+E+LSD  KR  YDTYGE+GL+
Sbjct: 122 AHEILSDKHKRTIYDTYGEKGLE 190
>13422
          Length = 930

 Score = 35.4 bits (80), Expect = 0.035,   Method: Compositional matrix adjust.
 Identities = 26/85 (30%), Positives = 41/85 (48%), Gaps = 8/85 (9%)
 Frame = +1

Query: 12  LLLYLIGTVIAGRDFYKILGVPR---SASIKDIKKAYRKLALQLHPDRNPD-----DPQA 63
           LLL L       +D Y +LG+ +    A+   IK+ YR+  L  HPD+        +   
Sbjct: 298 LLLGLNPKEWKKQDHYAVLGLSKLRYKATADHIKRIYRQKVLLHHPDKRRARGLHVENGE 477

Query: 64  QEKFQDLGAAYEVLSDSEKRKQYDT 88
            + F  +  AYE+L D  KR+ +D+
Sbjct: 478 NDYFLCISRAYEILGDPVKRRSFDS 552
>19018
          Length = 468

 Score = 33.9 bits (76), Expect = 0.10,   Method: Compositional matrix adjust.
 Identities = 15/44 (34%), Positives = 22/44 (50%), Gaps = 1/44 (2%)
 Frame = -2

Query: 286 HISRDKITRPGAKLWKKGEGLPNFDNNNIKGSLIITFD-VDFPK 328
           HISR K T   + LW+    +    NNNI+ + + T   + F K
Sbjct: 374 HISRQKSTHMSSSLWRNANSIEYIYNNNIQNAQMYTLSYIHFKK 243
>20155
          Length = 484

 Score = 29.3 bits (64), Expect = 2.6,   Method: Compositional matrix adjust.
 Identities = 15/28 (53%), Positives = 19/28 (67%)
 Frame = +1

Query: 29  ILGVPRSASIKDIKKAYRKLALQLHPDR 56
           ILGV  SAS   IK A++++ L  HPDR
Sbjct: 151 ILGVSPSASKVKIKDAHKRIMLLNHPDR 234
>18599
          Length = 452

 Score = 28.1 bits (61), Expect = 6.3,   Method: Compositional matrix adjust.
 Identities = 18/65 (27%), Positives = 31/65 (47%), Gaps = 13/65 (20%)
 Frame = +3

Query: 130 RGSDIIVDLEVTLEEVYAGNFVE-------------VVRNKPVARQAPGKRKCNCRQEMR 176
           RG+  ++ ++  LE+V  GN+++              VRN  VARQ   K+    R  ++
Sbjct: 51  RGTVRVLVMKQPLEDVLIGNYIQRGKGQSFEKIPVYAVRNMVVARQTQAKKFTEVRCSIK 230

Query: 177 TTQLG 181
            T+ G
Sbjct: 231 ATRTG 245
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|134288898|ref|NP_034548.2| hect (homologous to the
E6-AP (UBE3A) carboxyl terminus) domain and RCC1 (CHC1)-like domain
(RLD) 2 [Mus musculus]
         (4836 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

05524                                                                 255   e-128
26574                                                                 260   9e-69
05501                                                                 127   1e-28
32927                                                                 127   1e-28
02386                                                                 119   4e-26
02938                                                                 115   6e-25
33148                                                                  89   5e-17
21239                                                                  77   2e-13
20162                                                                  76   4e-13
13725                                                                  64   2e-09
38263                                                                  54   2e-06
03352                                                                  51   1e-05
19738                                                                  41   3e-05
39525                                                                  50   3e-05
12101                                                                  49   3e-05
33425                                                                  48   1e-04
14299                                                                  47   1e-04
07471                                                                  44   0.001
01993                                                                  37   0.14 
01451                                                                  37   0.18 
11020                                                                  35   0.69 
31200                                                                  35   1.0  
37466                                                                  34   1.5  
13682                                                                  33   2.2  
03889                                                                  33   2.9  
31463                                                                  32   4.4  
08616                                                                  32   8.7  
>05524
          Length = 2623

 Score =  255 bits (651), Expect(3) = e-128,   Method: Composition-based stats.
 Identities = 114/128 (89%), Positives = 120/128 (93%)
 Frame = +2

Query: 4677 CGSPDIPLHLLKSVATYKGIEPSASLVQWFWEVMESFSNTERSLFLRFVWGRTRLPRTIA 4736
            CGSPDIPL LLKSVATYKGIE +A LVQWFWEVM+ FS  ERSLFLRFVWGRTRLPRTIA
Sbjct: 491  CGSPDIPLTLLKSVATYKGIEATAPLVQWFWEVMDEFSTAERSLFLRFVWGRTRLPRTIA 670

Query: 4737 DFRGRDFVIQVLDKYNPPDHFLPESYTCFFLLKLPRYSCKQVLEEKLKYAIHFCKSIDTD 4796
            DFRGRDFV+QVLDKYNPPDHFLPESYTCFFLLK+PRYS K VL+EKLKYAIHFCKSIDTD
Sbjct: 671  DFRGRDFVLQVLDKYNPPDHFLPESYTCFFLLKMPRYSDKLVLKEKLKYAIHFCKSIDTD 850

Query: 4797 DYARIALT 4804
            DYAR+ALT
Sbjct: 851  DYARVALT 874

 Score =  132 bits (331), Expect(3) = e-128,   Method: Composition-based stats.
 Identities = 59/94 (62%), Positives = 77/94 (81%)
 Frame = +3

Query: 4512 ESGANRDCYLLNPATRAPVHCSMFRFLGVLLGIAIRTGSPLSLNLAEPVWKQLAGMSLTI 4571
            ESGANRDC+LLNP+  +P+H +MFRFLG+L+GIAIR+GSPLSL++AEP WKQLAGM L+I
Sbjct: 3    ESGANRDCFLLNPSLSSPLHQNMFRFLGILMGIAIRSGSPLSLSIAEPAWKQLAGMPLSI 182

Query: 4572 ADLSEVDKDFIPGLMYIRDNEATSEEFEAMSLPF 4605
            +DL+E+DKDF+PGL+ I+  E   E      +PF
Sbjct: 183  SDLTEMDKDFVPGLICIK--EMGEEGLRTADMPF 278

 Score =  114 bits (284), Expect(3) = e-128,   Method: Compositional matrix adjust.
 Identities = 52/73 (71%), Positives = 63/73 (86%)
 Frame = +1

Query: 4604 PFTVPSASGQDIQLSSKHTHITLDNRAEYVRLAINYRLHEFDEQVAAVREGMARVVPVPL 4663
            P +VPSA+GQ+ QLS KH+ I  DNRA+Y+++AINYRL EFD+QV  VREGM+RV+PVPL
Sbjct: 274  PSSVPSATGQETQLSHKHSRINPDNRADYIKMAINYRLQEFDQQVRWVREGMSRVIPVPL 453

Query: 4664 LSLFTGYELETMV 4676
            LSLFTG ELETMV
Sbjct: 454  LSLFTGLELETMV 492
>26574
          Length = 441

 Score =  260 bits (665), Expect = 9e-69,   Method: Compositional matrix adjust.
 Identities = 114/146 (78%), Positives = 132/146 (90%)
 Frame = +3

Query: 4222 TWGKGDYHRLGHGSDDHVRRPRQVQGLQGKKVIAIATGSLHCVCCTEDGEVYTWGDNDEG 4281
            TWGKGDYHRLGHG+DDHVRRPR+V  LQGKKVI +A GSLHCV CT+ GEV+TWGDNDEG
Sbjct: 3    TWGKGDYHRLGHGTDDHVRRPRRVSALQGKKVIDVACGSLHCVACTDSGEVFTWGDNDEG 182

Query: 4282 QLGDGTTNAIQRPRLVAALQGKKVNRVACGSAHTLAWSTSKPASAGKLPAQVPMEYNHLQ 4341
            QLGDGTTNAIQRPR+VAALQGKK+NRVACGSAH+LAWST KP SAG+LP+Q+PME+NHL 
Sbjct: 183  QLGDGTTNAIQRPRMVAALQGKKINRVACGSAHSLAWSTHKPVSAGRLPSQIPMEFNHLH 362

Query: 4342 EIPIIALRNRLLLLHHISELFCPCIP 4367
             + + +LRNRL+LLHH S+LFCP +P
Sbjct: 363  SLSMASLRNRLVLLHHFSDLFCPSLP 440

 Score =  144 bits (363), Expect = 9e-34,   Method: Compositional matrix adjust.
 Identities = 65/111 (58%), Positives = 85/111 (76%)
 Frame = +3

Query: 3229 TWGKGDYFRLGHGSDVHVRKPQVVEGLRGKKIVHVAVGALHCLAVTDSGQVYAWGDNDHG 3288
            TWGKGDY RLGHG+D HVR+P+ V  L+GKK++ VA G+LHC+A TDSG+V+ WGDND G
Sbjct: 3    TWGKGDYHRLGHGTDDHVRRPRRVSALQGKKVIDVACGSLHCVACTDSGEVFTWGDNDEG 182

Query: 3289 QQGNGTTTVNRKPTLVQGLEGQKITRVACGSSHSVAWTTVDVATPSVHEPV 3339
            Q G+GTT   ++P +V  L+G+KI RVACGS+HS+AW+T        H+PV
Sbjct: 183  QLGDGTTNAIQRPRMVAALQGKKINRVACGSAHSLAWST--------HKPV 311

 Score =  108 bits (269), Expect = 6e-23,   Method: Compositional matrix adjust.
 Identities = 59/126 (46%), Positives = 73/126 (57%)
 Frame = +3

Query: 681 SWGKGDNQRLGHGTEEHVRYPKLLEGLQGKKVIDVAAGSTHCLALTEDSEVHSWGSNDQC 740
           +WGKGD  RLGHGT++HVR P+ +  LQGKKVIDVA GS HC+A T+  EV +WG ND+ 
Sbjct: 3   TWGKGDYHRLGHGTDDHVRRPRRVSALQGKKVIDVACGSLHCVACTDSGEVFTWGDNDEG 182

Query: 741 QHFDTLRVTKPEPTALPGLDSKHIVGIACGPAQSFAWSSCSEWSIGLRVPFVVDICSMTF 800
           Q  D        P  +  L  K I  +ACG A S AWS+    S G R+P  +    M F
Sbjct: 183 QLGDGTTNAIQRPRMVAALQGKKINRVACGSAHSLAWSTHKPVSAG-RLPSQI---PMEF 350

Query: 801 EQLDLL 806
             L  L
Sbjct: 351 NHLHSL 368

 Score = 88.2 bits (217), Expect = 7e-17,   Method: Compositional matrix adjust.
 Identities = 43/98 (43%), Positives = 64/98 (65%)
 Frame = +3

Query: 3071 SWGEGDDGKLGHFSRMNCDKPRLIEALKTKRIRDIACGSSHSAALTSSGELYTWGLGEYG 3130
            +WG+GD  +LGH +  +  +PR + AL+ K++ D+ACGS H  A T SGE++TWG  + G
Sbjct: 3    TWGKGDYHRLGHGTDDHVRRPRRVSALQGKKVIDVACGSLHCVACTDSGEVFTWGDNDEG 182

Query: 3131 RLGHGDNTTQLKPKMVKVLLGHRVIQVACGSRDAQTLA 3168
            +LG G      +P+MV  L G ++ +VACGS  A +LA
Sbjct: 183  QLGDGTTNAIQRPRMVAALQGKKINRVACGS--AHSLA 290

 Score = 78.2 bits (191), Expect = 7e-14,   Method: Compositional matrix adjust.
 Identities = 35/91 (38%), Positives = 56/91 (61%)
 Frame = +3

Query: 4064 SWGEAEDGKLGHGNRSPCDRPRVIESLRGIEVVDVAAGGAHSACVTAAGDLYTWGKGRYG 4123
            +WG+ +  +LGHG      RPR + +L+G +V+DVA G  H    T +G+++TWG    G
Sbjct: 3    TWGKGDYHRLGHGTDDHVRRPRRVSALQGKKVIDVACGSLHCVACTDSGEVFTWGDNDEG 182

Query: 4124 RLGHSDSEDQLKPKLVEALQGHRVIDIACGS 4154
            +LG   +    +P++V ALQG ++  +ACGS
Sbjct: 183  QLGDGTTNAIQRPRMVAALQGKKINRVACGS 275

 Score = 73.6 bits (179), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 37/98 (37%), Positives = 56/98 (57%)
 Frame = +3

Query: 575 TWGRGNYGRLGHGSSEDEAIPMLVAGLKGLKVIDVACGSGDAQTLAVTENGQVWSWXXXX 634
           TWG+G+Y RLGHG+ +    P  V+ L+G KVIDVACGS     +A T++G+V++W    
Sbjct: 3   TWGKGDYHRLGHGTDDHVRRPRRVSALQGKKVIDVACGS--LHCVACTDSGEVFTWGDND 176

Query: 635 XXXXXXXXXXXCKTPKLIEKLQDLDVIKVRCGSQFSIA 672
                       + P+++  LQ   + +V CGS  S+A
Sbjct: 177 EGQLGDGTTNAIQRPRMVAALQGKKINRVACGSAHSLA 290

 Score = 71.2 bits (173), Expect = 8e-12,   Method: Compositional matrix adjust.
 Identities = 34/85 (40%), Positives = 49/85 (57%)
 Frame = +3

Query: 647 KTPKLIEKLQDLDVIKVRCGSQFSIALTKDGQVYSWGKGDNQRLGHGTEEHVRYPKLLEG 706
           + P+ +  LQ   VI V CGS   +A T  G+V++WG  D  +LG GT   ++ P+++  
Sbjct: 57  RRPRRVSALQGKKVIDVACGSLHCVACTDSGEVFTWGDNDEGQLGDGTTNAIQRPRMVAA 236

Query: 707 LQGKKVIDVAAGSTHCLALTEDSEV 731
           LQGKK+  VA GS H LA +    V
Sbjct: 237 LQGKKINRVACGSAHSLAWSTHKPV 311

 Score = 68.9 bits (167), Expect = 5e-11,   Method: Compositional matrix adjust.
 Identities = 36/98 (36%), Positives = 51/98 (52%)
 Frame = +3

Query: 3123 TWGLGEYGRLGHGDNTTQLKPKMVKVLLGHRVIQVACGSRDAQTLALTDEGLVFSWXXXX 3182
            TWG G+Y RLGHG +    +P+ V  L G +VI VACGS     +A TD G VF+W    
Sbjct: 3    TWGKGDYHRLGHGTDDHVRRPRRVSALQGKKVIDVACGS--LHCVACTDSGEVFTWGDND 176

Query: 3183 XXXXXXXXSEGCNIPQNIERLNGQGVCQIECGAQFSLA 3220
                    +     P+ +  L G+ + ++ CG+  SLA
Sbjct: 177  EGQLGDGTTNAIQRPRMVAALQGKKINRVACGSAHSLA 290

 Score = 68.2 bits (165), Expect = 8e-11,   Method: Compositional matrix adjust.
 Identities = 39/100 (39%), Positives = 59/100 (59%)
 Frame = +3

Query: 3018 GEATNGRLGLGMSSGTVPIPRQITALSSYVVKKVAVHSGGRHATALTVDGKVFSWGEGDD 3077
            G+    RLG G +   V  PR+++AL    V  VA   G  H  A T  G+VF+WG+ D+
Sbjct: 9    GKGDYHRLGHG-TDDHVRRPRRVSALQGKKVIDVAC--GSLHCVACTDSGEVFTWGDNDE 179

Query: 3078 GKLGHFSRMNCDKPRLIEALKTKRIRDIACGSSHSAALTS 3117
            G+LG  +     +PR++ AL+ K+I  +ACGS+HS A ++
Sbjct: 180  GQLGDGTTNAIQRPRMVAALQGKKINRVACGSAHSLAWST 299

 Score = 65.5 bits (158), Expect = 5e-10,   Method: Compositional matrix adjust.
 Identities = 35/85 (41%), Positives = 52/85 (61%)
 Frame = +3

Query: 536 LEEPKVISAFSGKQAGKHVVHIACGSTYSAAITAEGELYTWGRGNYGRLGHGSSEDEAIP 595
           +  P+ +SA  GK+    V+ +ACGS +  A T  GE++TWG  + G+LG G++     P
Sbjct: 54  VRRPRRVSALQGKK----VIDVACGSLHCVACTDSGEVFTWGDNDEGQLGDGTTNAIQRP 221

Query: 596 MLVAGLKGLKVIDVACGSGDAQTLA 620
            +VA L+G K+  VACGS  A +LA
Sbjct: 222 RMVAALQGKKINRVACGS--AHSLA 290

 Score = 63.2 bits (152), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 33/85 (38%), Positives = 50/85 (58%)
 Frame = +3

Query: 3197 PQNIERLNGQGVCQIECGAQFSLALTKSGVVWTWGKGDYFRLGHGSDVHVRKPQVVEGLR 3256
            P+ +  L G+ V  + CG+   +A T SG V+TWG  D  +LG G+   +++P++V  L+
Sbjct: 63   PRRVSALQGKKVIDVACGSLHCVACTDSGEVFTWGDNDEGQLGDGTTNAIQRPRMVAALQ 242

Query: 3257 GKKIVHVAVGALHCLAVTDSGQVYA 3281
            GKKI  VA G+ H LA +    V A
Sbjct: 243  GKKINRVACGSAHSLAWSTHKPVSA 317

 Score = 59.7 bits (143), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 26/64 (40%), Positives = 42/64 (65%)
 Frame = +3

Query: 4042 KKVAVNSGGKHCLALSSEGEVYSWGEAEDGKLGHGNRSPCDRPRVIESLRGIEVVDVAAG 4101
            K + V  G  HC+A +  GEV++WG+ ++G+LG G  +   RPR++ +L+G ++  VA G
Sbjct: 93   KVIDVACGSLHCVACTDSGEVFTWGDNDEGQLGDGTTNAIQRPRMVAALQGKKINRVACG 272

Query: 4102 GAHS 4105
             AHS
Sbjct: 273  SAHS 284

 Score = 40.0 bits (92), Expect = 0.020,   Method: Compositional matrix adjust.
 Identities = 22/82 (26%), Positives = 41/82 (50%)
 Frame = +3

Query: 485 PQLVQGLASRNIVKIAAHSDGHHYLALAATGEVYSWXXXXXXXXXXXDTVPLEEPKVISA 544
           P+ V  L  + ++ +A  S   H +A   +GEV++W            T  ++ P++++A
Sbjct: 63  PRRVSALQGKKVIDVACGSL--HCVACTDSGEVFTWGDNDEGQLGDGTTNAIQRPRMVAA 236

Query: 545 FSGKQAGKHVVHIACGSTYSAA 566
             GK+  +    +ACGS +S A
Sbjct: 237 LQGKKINR----VACGSAHSLA 290
>05501
          Length = 1740

 Score =  127 bits (319), Expect = 1e-28,   Method: Compositional matrix adjust.
 Identities = 101/366 (27%), Positives = 164/366 (44%), Gaps = 10/366 (2%)
 Frame = -1

Query: 4432 SKGGLAGPDGTKSVFGQMCAKMSSFSPDSLLLPHRVWKVKFVGESVDDCGGGYSESIAEI 4491
            SK  L G    +  F Q+  ++  F      L  R++ + F GE   D GG   E    +
Sbjct: 1713 SKSMLHGKISYEDSFAQI-MRLQPFD-----LRRRLYII-FKGEEGLDYGGVAREWFFHL 1555

Query: 4492 CEELQNGLTPLLIVTPNGRDESGANRDCYL-LNPATRA-PVHCSMFRFLGVLLGIAIRTG 4549
              ++ N +  L         E  +N +  L +NPA+   P H   FRF+G  + +A+  G
Sbjct: 1554 SHDVLNPMYCLF--------EYASNNNYSLQINPASSVNPDHLLYFRFIGRFIAMALYHG 1399

Query: 4550 SPLSLNLAEPVWKQLAGMSLTIADLSEVDKDFIPGLMYIRDNEATSEEFEAMSLP-FTV- 4607
              +      P +K++    LT+ DL  +D ++   L +++DN       E      F V 
Sbjct: 1398 KFIDSGFTLPFYKRMLSKKLTLKDLETIDGEYFQSLQWVKDNNVEESGLELFFCADFEVL 1219

Query: 4608 PSASGQDIQLSSKHTHITLDNRAEYVRLAINYRLHE-FDEQVAAVREGMARVVPVPLLSL 4666
                  +++       +T +N+ EY+ L   +R     +EQ  A  EG   VVP+  L  
Sbjct: 1218 GKVENHELKPGGSEIKVTEENKEEYLNLMTQWRFSRGVEEQTKAFLEGFNEVVPLQWLQY 1039

Query: 4667 FTGYELETMVCGSPDIPLHLLKSVATYKGIEPSASLVQWFWEVMESFSNTERSLFLRFVW 4726
            F   ELE M+CG  ++ +   +    Y+  + ++  V WFW+ +    N +R+  L+FV 
Sbjct: 1038 FDERELELMLCGMQEVDVDDWERNTIYRHYQRNSKQVTWFWKFVREIDNEKRTRLLQFVT 859

Query: 4727 GRTRLPR-TIADFRGRD----FVIQVLDKYNPPDHFLPESYTCFFLLKLPRYSCKQVLEE 4781
            G  RLP    A+  G +    F I+ + K    + +LP S+TCF  + LP Y   + L E
Sbjct: 858  GTCRLPVGGFAELMGSNGPQRFCIEKVGK----ETWLPRSHTCFNRIDLPPYRSYEQLVE 691

Query: 4782 KLKYAI 4787
            KL  AI
Sbjct: 690  KLNLAI 673
>32927
          Length = 514

 Score =  127 bits (319), Expect = 1e-28,   Method: Composition-based stats.
 Identities = 57/67 (85%), Positives = 63/67 (94%)
 Frame = +3

Query: 4741 RDFVIQVLDKYNPPDHFLPESYTCFFLLKLPRYSCKQVLEEKLKYAIHFCKSIDTDDYAR 4800
            RDFV+QVL+K NPPDHFLPESYTCFFLLK+PRYSCK VL EKLKYAIHFCKSIDTD+YAR
Sbjct: 3    RDFVLQVLEK-NPPDHFLPESYTCFFLLKMPRYSCKTVLLEKLKYAIHFCKSIDTDEYAR 179

Query: 4801 IALTGEP 4807
            +A+ GEP
Sbjct: 180  VAM-GEP 197
>02386
          Length = 2222

 Score =  119 bits (297), Expect = 4e-26,   Method: Compositional matrix adjust.
 Identities = 96/343 (27%), Positives = 153/343 (44%), Gaps = 20/343 (5%)
 Frame = +2

Query: 4468 WKVKFV----GESVDDCGGGYSESIAEICEELQNGLTPLLIVTPNGRDESGANRD--CYL 4521
            WK +F     GE   D GG   E    I  E+ N    L    P         RD   Y 
Sbjct: 404  WKQRFYIVFEGEEGQDAGGLLREWYLIISREIFNENYVLFKRYP---------RDGVTYT 556

Query: 4522 LNPATR-APVHCSMFRFLGVLLGIAIRTGSPLSLNLAEPVWKQLAGMSLTIADLSEVDKD 4580
            +NP++     H S F+F+G ++  AI     L        +K + G+ +   D+   D  
Sbjct: 557  INPSSHFNSNHLSYFKFVGRIIAKAIYDNKLLECYFTRSFYKHVLGLPVKYTDMECEDIM 736

Query: 4581 FIPGLMYIRDNEATSE-------EFEAMSLPFTVPSASGQDIQLSSKHTHITLDNRAEYV 4633
            F   L+++ +N+ T          F A    F V     +D+  +  +  +T +N+ EYV
Sbjct: 737  FYQSLVFLLENDITDMGAALGDLNFSAEVEEFGVRET--RDLIENGSNIGVTEENKREYV 910

Query: 4634 RLAINYRLH-EFDEQVAAVREGMARVVPVPLLSLFTGYELETMVCGSPDIPLHLLKSVAT 4692
            +L    ++     +Q+ A  EG   ++P  L+++FT  ELE ++ G P I +  LK+   
Sbjct: 911  KLVCQMKMTGAIRQQLNAFLEGFYDIIPKKLVAIFTEQELELLISGLPTIDIDDLKANTE 1090

Query: 4693 YKGIEPSASLVQWFWEVMESFSNTERSLFLRFVWGRTRLP-RTIADFRGRD----FVIQV 4747
            Y   +P++  +QWFW  + SF   ER+ FL+FV G +++P +  A   G +    F I  
Sbjct: 1091 YHKYQPTSLQIQWFWRALRSFDQAERANFLQFVTGTSKVPLQGFATLEGMNGHQKFQIHR 1270

Query: 4748 LDKYNPPDHFLPESYTCFFLLKLPRYSCKQVLEEKLKYAIHFC 4790
             D+       LP ++TCF  L LP Y     L + L  A+  C
Sbjct: 1271 DDRSTDR---LPSAHTCFNQLDLPAYETYDKLRKMLLLAVSEC 1390
>02938
          Length = 1718

 Score =  115 bits (287), Expect = 6e-25,   Method: Compositional matrix adjust.
 Identities = 84/264 (31%), Positives = 136/264 (51%), Gaps = 2/264 (0%)
 Frame = +3

Query: 3067 GKVFSWGEGDDGKLGHFSRMNCDKPRLIEALKTKRIRDIACGSSHSAALTSSGELYTWGL 3126
            G+VF +G  D G+LG  ++   ++P  +++LK ++ R +ACG SH+   T SG +Y +G 
Sbjct: 15   GRVFMFGPNDYGQLGIGAQKVANRPSCVKSLKHEKARLVACGRSHTIVATESGNIYAFGA 194

Query: 3127 GEYGRLGHGDNTTQLKPKMVKVLLGHRVIQVACGSRDAQTLALTDEGLVFSWXXXXXXXX 3186
               G+LG    T    PK V  L       +A G     +LALT++G VF W        
Sbjct: 195  NGEGQLGVEGVTETNLPKQVDSLQATPWKMLAAGCD--HSLALTEDGRVFVWGGNGEGQL 368

Query: 3187 XXXXSEGCNIPQNIERLNGQGVCQIECGAQFSLALTKSGVVWTWGKGDYFRLGHGSDV-H 3245
                     +P+ ++   GQ V  I  G   S  +T+SG ++T+G+ D  +LG   D   
Sbjct: 369  GMGEDSDIPVPRQLDV--GQSVACIASGYYHSALVTESGELYTFGESDGGKLGLNGDTDE 542

Query: 3246 VRKPQVVEGLRGKKIVHVAVGALHCLAVTDSGQVYAWGDNDHGQQGNGTTTV-NRKPTLV 3304
             + PQ V  +   K+  V+ G  H +A+T+ G+VYA+G+   GQ G G +T+ +  P+L+
Sbjct: 543  CKTPQQVMAIN-DKVKSVSCGGSHTVALTEKGEVYAFGEGSSGQLGLGVSTLESESPSLL 719

Query: 3305 QGLEGQKITRVACGSSHSVAWTTV 3328
            +     K+ +V CG +    +TTV
Sbjct: 720  K--LPFKVAQVCCGEN----FTTV 773

 Score =  110 bits (276), Expect = 1e-23,   Method: Compositional matrix adjust.
 Identities = 83/262 (31%), Positives = 129/262 (49%), Gaps = 2/262 (0%)
 Frame = +3

Query: 4060 GEVYSWGEAEDGKLGHGNRSPCDRPRVIESLRGIEVVDVAAGGAHSACVTAAGDLYTWGK 4119
            G V+ +G  + G+LG G +   +RP  ++SL+  +   VA G +H+   T +G++Y +G 
Sbjct: 15   GRVFMFGPNDYGQLGIGAQKVANRPSCVKSLKHEKARLVACGRSHTIVATESGNIYAFGA 194

Query: 4120 GRYGRLGHSDSEDQLKPKLVEALQGHRVIDIACGSGDAQTLCLTDDDTVWSWXXXXXXXX 4179
               G+LG     +   PK V++LQ      +A G     +L LT+D  V+ W        
Sbjct: 195  NGEGQLGVEGVTETNLPKQVDSLQATPWKMLAAGC--DHSLALTEDGRVFVWGGNGEGQL 368

Query: 4180 XXXXXXXCKVPMKIDSLTGLGVVKVECGSQFSVALTKSGAVYTWGKGDYHRLG-HGSDDH 4238
                     VP ++D   G  V  +  G   S  +T+SG +YT+G+ D  +LG +G  D 
Sbjct: 369  GMGEDSDIPVPRQLD--VGQSVACIASGYYHSALVTESGELYTFGESDGGKLGLNGDTDE 542

Query: 4239 VRRPRQVQGLQGKKVIAIATGSLHCVCCTEDGEVYTWGDNDEGQLGDG-TTNAIQRPRLV 4297
             + P+QV  +   KV +++ G  H V  TE GEVY +G+   GQLG G +T   + P L+
Sbjct: 543  CKTPQQVMAIN-DKVKSVSCGGSHTVALTEKGEVYAFGEGSSGQLGLGVSTLESESPSLL 719

Query: 4298 AALQGKKVNRVACGSAHTLAWS 4319
                  KV +V CG   T   S
Sbjct: 720  KLP--FKVAQVCCGENFTTVVS 779

 Score =  100 bits (250), Expect = 1e-20,   Method: Compositional matrix adjust.
 Identities = 89/349 (25%), Positives = 153/349 (43%), Gaps = 10/349 (2%)
 Frame = +3

Query: 3010 VEGKVYSCGEATNGRLGLGMSSGTVPIPRQITALSSYVVKKVAVHSGGRHATALTVDGKV 3069
            + G+V+  G    G+LG+G        P  + +L     + VA   G  H    T  G +
Sbjct: 9    IYGRVFMFGPNDYGQLGIGAQK-VANRPSCVKSLKHEKARLVAC--GRSHTIVATESGNI 179

Query: 3070 FSWGEGDDGKLGHFSRMNCDKPRLIEALKTKRIRDIACGSSHSAALTSSGELYTWGLGEY 3129
            +++G   +G+LG       + P+ +++L+    + +A G  HS ALT  G ++ WG    
Sbjct: 180  YAFGANGEGQLGVEGVTETNLPKQVDSLQATPWKMLAAGCDHSLALTEDGRVFVWGGNGE 359

Query: 3130 GRLGHGDNTTQLKPKMVKVLLGHRVIQVACGSRDAQTLALTDEGLVFSWXXXXXXXXXXX 3189
            G+LG G+++    P+ + V  G  V  +A G   +  +  + E   F             
Sbjct: 360  GQLGMGEDSDIPVPRQLDV--GQSVACIASGYYHSALVTESGELYTFGESDGGKLGLNGD 533

Query: 3190 XSEGCNIPQNIERLNGQGVCQIECGAQFSLALTKSGVVWTWGKGDYFRLGHG-SDVHVRK 3248
              E C  PQ +  +N + V  + CG   ++ALT+ G V+ +G+G   +LG G S +    
Sbjct: 534  TDE-CKTPQQVMAINDK-VKSVSCGGSHTVALTEKGEVYAFGEGSSGQLGLGVSTLESES 707

Query: 3249 PQVVEGLRGKKIVHVAVGALHCLAVTDSGQVYAWGDNDHGQQGNGTTTVNRK--PTLVQG 3306
            P +++     K+  V  G      V++ GQ+Y +GD  HG+   G  + + +   T V  
Sbjct: 708  PSLLK--LPFKVAQVCCGENFTTVVSERGQLYTFGDGRHGKLALGQESFSNQFVCTKVDR 881

Query: 3307 LEGQKITRVACGSSHSVAWTTV-----DVATPSVHEPVLFQ--TARDPL 3348
                 + + ACG  H +   +      DVA+    E  +    T RD L
Sbjct: 882  FLKFNVKKAACGGCHLIVMASPKLENGDVASEDEEEGQIMMNGTIRDSL 1028

 Score = 98.2 bits (243), Expect = 7e-20,   Method: Compositional matrix adjust.
 Identities = 66/203 (32%), Positives = 105/203 (51%), Gaps = 3/203 (1%)
 Frame = +3

Query: 2961 KVFVWGLNDKDQLGGLKGSKIKVPSFSETLSALNVVQVAGGSKSLFAVTVEGKVYSCGEA 3020
            +VFVWG N + QLG  + S I VP   +     +V  +A G      VT  G++Y+ GE+
Sbjct: 330  RVFVWGGNGEGQLGMGEDSDIPVPRQLDV--GQSVACIASGYYHSALVTESGELYTFGES 503

Query: 3021 TNGRLGLGMSSGTVPIPRQITALSSYVVKKVAVHSGGRHATALTVDGKVFSWGEGDDGKL 3080
              G+LGL   +     P+Q+ A++  V    +V  GG H  ALT  G+V+++GEG  G+L
Sbjct: 504  DGGKLGLNGDTDECKTPQQVMAINDKV---KSVSCGGSHTVALTEKGEVYAFGEGSSGQL 674

Query: 3081 G-HFSRMNCDKPRLIEALKTKRIRDIACGSSHSAALTSSGELYTWGLGEYGRLGHGDN-- 3137
            G   S +  + P L++     ++  + CG + +  ++  G+LYT+G G +G+L  G    
Sbjct: 675  GLGVSTLESESPSLLKL--PFKVAQVCCGENFTTVVSERGQLYTFGDGRHGKLALGQESF 848

Query: 3138 TTQLKPKMVKVLLGHRVIQVACG 3160
            + Q     V   L   V + ACG
Sbjct: 849  SNQFVCTKVDRFLKFNVKKAACG 917

 Score = 90.1 bits (222), Expect = 2e-17,   Method: Compositional matrix adjust.
 Identities = 76/298 (25%), Positives = 136/298 (45%), Gaps = 5/298 (1%)
 Frame = +3

Query: 4030 PTLLESIQHVFIKKVAVNSGGKHCLALSSEGEVYSWGEAEDGKLGHGNRSPCDRPRVIES 4089
            P+ ++S++H   + VA   G  H +  +  G +Y++G   +G+LG    +  + P+ ++S
Sbjct: 87   PSCVKSLKHEKARLVAC--GRSHTIVATESGNIYAFGANGEGQLGVEGVTETNLPKQVDS 260

Query: 4090 LRGIEVVDVAAGGAHSACVTAAGDLYTWGKGRYGRLGHSDSEDQLKPKLVEALQGHRVID 4149
            L+      +AAG  HS  +T  G ++ WG    G+LG  +  D   P+ ++  Q      
Sbjct: 261  LQATPWKMLAAGCDHSLALTEDGRVFVWGGNGEGQLGMGEDSDIPVPRQLDVGQ-----S 425

Query: 4150 IAC-GSGDAQTLCLTDDDTVWSWXXXXXXX-XXXXXXXXCKVPMKIDSLTGLGVVKVECG 4207
            +AC  SG   +  +T+   ++++                CK P ++ ++    V  V CG
Sbjct: 426  VACIASGYYHSALVTESGELYTFGESDGGKLGLNGDTDECKTPQQVMAINDK-VKSVSCG 602

Query: 4208 SQFSVALTKSGAVYTWGKGDYHRLGHGSDDHVRRPRQVQGLQGKKVIAIATGSLHCVCCT 4267
               +VALT+ G VY +G+G   +LG G          +  L   KV  +  G       +
Sbjct: 603  GSHTVALTEKGEVYAFGEGSSGQLGLGVSTLESESPSLLKLP-FKVAQVCCGENFTTVVS 779

Query: 4268 EDGEVYTWGDNDEGQLGDGT---TNAIQRPRLVAALQGKKVNRVACGSAHTLAWSTSK 4322
            E G++YT+GD   G+L  G    +N     ++   L+   V + ACG  H +  ++ K
Sbjct: 780  ERGQLYTFGDGRHGKLALGQESFSNQFVCTKVDRFLK-FNVKKAACGGCHLIVMASPK 950

 Score = 82.8 bits (203), Expect = 3e-15,   Method: Compositional matrix adjust.
 Identities = 69/253 (27%), Positives = 118/253 (46%), Gaps = 14/253 (5%)
 Frame = +3

Query: 457 VACAEKRFLILSRNGRVYTQAYNSDMLAPQLVQGLASRNIVK------------IAAHSD 504
           VAC     ++ + +G +Y  A+ ++      V+G+   N+ K            +AA  D
Sbjct: 129 VACGRSHTIVATESGNIY--AFGANGEGQLGVEGVTETNLPKQVDSLQATPWKMLAAGCD 302

Query: 505 GHHYLALAATGEVYSWXXXXXXXXXXXDTVPLEEPKVISAFSGKQAGKHVVHIACGSTYS 564
             H LAL   G V+ W           +   +  P+ +        G+ V  IA G  +S
Sbjct: 303 --HSLALTEDGRVFVWGGNGEGQLGMGEDSDIPVPRQLDV------GQSVACIASGYYHS 458

Query: 565 AAITAEGELYTWGRGNYGRLG-HGSSEDEAIPMLVAGLKGLKVIDVACGSGDAQTLAVTE 623
           A +T  GELYT+G  + G+LG +G +++   P  V  +   KV  V+CG   + T+A+TE
Sbjct: 459 ALVTESGELYTFGESDGGKLGLNGDTDECKTPQQVMAIND-KVKSVSCGG--SHTVALTE 629

Query: 624 NGQVWSWXXXXXXX-XXXXXXXXCKTPKLIEKLQDLDVIKVRCGSQFSIALTKDGQVYSW 682
            G+V+++                 ++P L+ KL    V +V CG  F+  +++ GQ+Y++
Sbjct: 630 KGEVYAFGEGSSGQLGLGVSTLESESPSLL-KL-PFKVAQVCCGENFTTVVSERGQLYTF 803

Query: 683 GKGDNQRLGHGTE 695
           G G + +L  G E
Sbjct: 804 GDGRHGKLALGQE 842

 Score = 80.1 bits (196), Expect = 2e-14,   Method: Compositional matrix adjust.
 Identities = 49/168 (29%), Positives = 84/168 (50%)
 Frame = +3

Query: 571 GELYTWGRGNYGRLGHGSSEDEAIPMLVAGLKGLKVIDVACGSGDAQTLAVTENGQVWSW 630
           G ++ +G  +YG+LG G+ +    P  V  LK  K   VACG   + T+  TE+G ++++
Sbjct: 15  GRVFMFGPNDYGQLGIGAQKVANRPSCVKSLKHEKARLVACGR--SHTIVATESGNIYAF 188

Query: 631 XXXXXXXXXXXXXXXCKTPKLIEKLQDLDVIKVRCGSQFSIALTKDGQVYSWGKGDNQRL 690
                             PK ++ LQ      +  G   S+ALT+DG+V+ WG     +L
Sbjct: 189 GANGEGQLGVEGVTETNLPKQVDSLQATPWKMLAAGCDHSLALTEDGRVFVWGGNGEGQL 368

Query: 691 GHGTEEHVRYPKLLEGLQGKKVIDVAAGSTHCLALTEDSEVHSWGSND 738
           G G +  +  P+ L+   G+ V  +A+G  H   +TE  E++++G +D
Sbjct: 369 GMGEDSDIPVPRQLD--VGQSVACIASGYYHSALVTESGELYTFGESD 506

 Score = 63.5 bits (153), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 61/221 (27%), Positives = 93/221 (42%), Gaps = 12/221 (5%)
 Frame = +3

Query: 3945 DWTLSAGGSGTIYGWGHNHRGQLGGIEGAKVKVP--------TPCEALATLRPVQLI-GG 3995
            D +L+    G ++ WG N  GQLG  E + + VP          C A        +   G
Sbjct: 300  DHSLALTEDGRVFVWGGNGEGQLGMGEDSDIPVPRQLDVGQSVACIASGYYHSALVTESG 479

Query: 3996 EQTLFAVTADGKXXXXXXXXXXXXXXXXXESVSTPTLLESIQHVFIKKVAVNSGGKHCLA 4055
            E   F  +  GK                 +   TP  + +I     K  +V+ GG H +A
Sbjct: 480  ELYTFGESDGGK----------LGLNGDTDECKTPQQVMAIND---KVKSVSCGGSHTVA 620

Query: 4056 LSSEGEVYSWGEAEDGKLGHGNRS-PCDRPRVIESLRGIEVVDVAAGGAHSACVTAAGDL 4114
            L+ +GEVY++GE   G+LG G  +   + P +++     +V  V  G   +  V+  G L
Sbjct: 621  LTEKGEVYAFGEGSSGQLGLGVSTLESESPSLLK--LPFKVAQVCCGENFTTVVSERGQL 794

Query: 4115 YTWGKGRYGR--LGHSDSEDQLKPKLVEALQGHRVIDIACG 4153
            YT+G GR+G+  LG     +Q     V+      V   ACG
Sbjct: 795  YTFGDGRHGKLALGQESFSNQFVCTKVDRFLKFNVKKAACG 917

 Score = 55.1 bits (131), Expect = 7e-07,   Method: Compositional matrix adjust.
 Identities = 31/93 (33%), Positives = 44/93 (47%)
 Frame = +3

Query: 649 PKLIEKLQDLDVIKVRCGSQFSIALTKDGQVYSWGKGDNQRLGHGTEEHVRYPKLLEGLQ 708
           P  ++ L+      V CG   +I  T+ G +Y++G     +LG         PK ++ LQ
Sbjct: 87  PSCVKSLKHEKARLVACGRSHTIVATESGNIYAFGANGEGQLGVEGVTETNLPKQVDSLQ 266

Query: 709 GKKVIDVAAGSTHCLALTEDSEVHSWGSNDQCQ 741
                 +AAG  H LALTED  V  WG N + Q
Sbjct: 267 ATPWKMLAAGCDHSLALTEDGRVFVWGGNGEGQ 365

 Score = 47.0 bits (110), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 22/52 (42%), Positives = 30/52 (57%)
 Frame = +3

Query: 4270 GEVYTWGDNDEGQLGDGTTNAIQRPRLVAALQGKKVNRVACGSAHTLAWSTS 4321
            G V+ +G ND GQLG G      RP  V +L+ +K   VACG +HT+  + S
Sbjct: 15   GRVFMFGPNDYGQLGIGAQKVANRPSCVKSLKHEKARLVACGRSHTIVATES 170
>33148
          Length = 687

 Score = 88.6 bits (218), Expect = 5e-17,   Method: Composition-based stats.
 Identities = 48/110 (43%), Positives = 62/110 (56%)
 Frame = +3

Query: 4687 LKSVATYKGIEPSASLVQWFWEVMESFSNTERSLFLRFVWGRTRLPRTIADFRGRDFVIQ 4746
            L     Y  +E +   V++FWE M++FSN +RS FLRFV GR RLP  +    G+   I 
Sbjct: 18   LSKTTYYDDLEETDIRVKYFWEAMKAFSNEDRSRFLRFVTGRRRLPAPLVISTGKGDTID 197

Query: 4747 VLDKYNPPDHFLPESYTCFFLLKLPRYSCKQVLEEKLKYAIHFCKSIDTD 4796
                       LPES TC  +L LP YS  +V EEKL+YA + C +IDTD
Sbjct: 198  S----------LPESSTCANMLYLPYYSSAKVAEEKLRYAAYNCIAIDTD 317
>21239
          Length = 1264

 Score = 77.0 bits (188), Expect = 2e-13,   Method: Compositional matrix adjust.
 Identities = 64/206 (31%), Positives = 96/206 (46%), Gaps = 10/206 (4%)
 Frame = +1

Query: 4591 NEATSEEFEAMSLPFTVPSASGQDIQLSS--KHTHITLDNRAEYVRLAINYRLHE-FDEQ 4647
            +E   ++ + + L F +P   G +I+L    K   +TL N  EY++L I++ L E    Q
Sbjct: 55   SEVLIQDIQDLGLYFHLP---GYNIELKKGGKDIPVTLHNLHEYLQLVIHWSLVEGVSRQ 225

Query: 4648 VAAVREGMARVVPVPLLSLFTGYELETMVCGSPDIPLH---LLKSVATYKGIEPSASLVQ 4704
              A REG   V  +  L  F   ELE + CGS   P     L+++     G    +  V 
Sbjct: 226  FEAFREGFESVFSLSSLQCFYPEELEQLFCGSQWGPWEVKMLMENCRPDHGYTHDSKAVV 405

Query: 4705 WFWEVMESFSNTERSLFLRFVWGRTRLPRTIADFRGRD----FVIQVLDKYNPPDHFLPE 4760
            + ++++ SF   ++  FL+FV G  RLP  +  FR        V +  +    PD FLP 
Sbjct: 406  FLYQLLASFDLQQQRHFLQFVTGSPRLP--VGGFRSLTPPLTIVRKTFEAGENPDDFLPS 579

Query: 4761 SYTCFFLLKLPRYSCKQVLEEKLKYA 4786
              TC   LKLP YS   ++  KL  A
Sbjct: 580  VMTCVNYLKLPDYSSIDIMRHKLHTA 657
>20162
          Length = 1121

 Score = 75.9 bits (185), Expect = 4e-13,   Method: Compositional matrix adjust.
 Identities = 67/246 (27%), Positives = 106/246 (43%), Gaps = 29/246 (11%)
 Frame = +1

Query: 3057 GRHATALTVDGKVFSWGEGDDGKLGHFS-----------RMNCD-KPRLIEALKTKR--- 3101
            G  +T   ++G ++S+G  + G+LGH S              C+  PR +     K    
Sbjct: 106  GEFSTMSDINGNLYSFGCPEYGQLGHNSDGKYFVTSNKMEYKCEMTPRKVSVFIEKTRDG 285

Query: 3102 ---------IRDIACGSSHSAALTSSGELYTWGLGEYGRLGHGDNTTQLKPKMVKVL--L 3150
                     IR++ACG +H+  + S   L++WG G YGRLGH +   +L P+++K     
Sbjct: 286  HVMPITDVDIREVACGLNHTLIMDSKKRLFSWGFGGYGRLGHAEPKDELVPRLIKFFDGP 465

Query: 3151 GHRVIQVACGSRDAQTLALTDEGLVFSWXXXXXXXXXXXXSEGCNIPQNIERLNGQGVCQ 3210
            G    Q+ CGS    T  + + G ++ W             E    P+ ++ L+G  V  
Sbjct: 466  GRGGSQIQCGSSFCMT--VNEHGALYFW------GQSKPTGEATMYPKLVQDLSGWKVRS 621

Query: 3211 IECGAQFSLALTKSGVVWTWGKG-DYFRLGHGSDVHVRK--PQVVEGLRGKKIVHVAVGA 3267
            I C  + S+ L     V +WG    Y  LG+G +        Q V+ L G  +  VA G 
Sbjct: 622  IGCCYR-SIVLCADDSVVSWGPSPTYGELGYGENKMKSSTVAQEVKPLDGVYVHDVACGY 798

Query: 3268 LHCLAV 3273
             H L +
Sbjct: 799  AHTLMI 816

 Score = 73.9 bits (180), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 77/285 (27%), Positives = 116/285 (40%), Gaps = 28/285 (9%)
 Frame = +1

Query: 4060 GEVYSWGEAEDGKLGHGN-----------RSPCD-RPR----VIESLRG--------IEV 4095
            G +YS+G  E G+LGH +              C+  PR     IE  R         +++
Sbjct: 136  GNLYSFGCPEYGQLGHNSDGKYFVTSNKMEYKCEMTPRKVSVFIEKTRDGHVMPITDVDI 315

Query: 4096 VDVAAGGAHSACVTAAGDLYTWGKGRYGRLGHSDSEDQLKPKLVEALQGHRVIDIACGSG 4155
             +VA G  H+  + +   L++WG G YGRLGH++ +D+L P+L++   G        G G
Sbjct: 316  REVACGLNHTLIMDSKKRLFSWGFGGYGRLGHAEPKDELVPRLIKFFDGP-------GRG 474

Query: 4156 DAQTLCLTDDDTVWSWXXXXXXXXXXXXXXXCKVPMKIDSLTGLGVVKVECGSQFSVALT 4215
             +Q  C                                             GS F + + 
Sbjct: 475  GSQIQC---------------------------------------------GSSFCMTVN 519

Query: 4216 KSGAVYTWGKGDYHRLGHGSDDHVRRPRQVQGLQGKKVIAIATGSLHCVCCTEDGEVYTW 4275
            + GA+Y WG+         + +    P+ VQ L G KV +I       V C +D  V +W
Sbjct: 520  EHGALYFWGQSK------PTGEATMYPKLVQDLSGWKVRSIGCCYRSIVLCADD-SVVSW 678

Query: 4276 GDN-DEGQLGDGTTNAIQRPRL---VAALQGKKVNRVACGSAHTL 4316
            G +   G+LG G  N ++   +   V  L G  V+ VACG AHTL
Sbjct: 679  GPSPTYGELGYG-ENKMKSSTVAQEVKPLDGVYVHDVACGYAHTL 810

 Score = 71.6 bits (174), Expect = 7e-12,   Method: Compositional matrix adjust.
 Identities = 58/209 (27%), Positives = 89/209 (42%), Gaps = 15/209 (7%)
 Frame = +1

Query: 539 PKVISAFSGKQAGKHVV--------HIACGSTYSAAITAEGELYTWGRGNYGRLGHGSSE 590
           P+ +S F  K    HV+         +ACG  ++  + ++  L++WG G YGRLGH   +
Sbjct: 244 PRKVSVFIEKTRDGHVMPITDVDIREVACGLNHTLIMDSKKRLFSWGFGGYGRLGHAEPK 423

Query: 591 DEAIPMLVAGLKGLKVIDVACGSGDAQTLAVTENGQVWSWXXXXXXXXXXXXXXXCKTPK 650
           DE +P L+    G          G +  + V E+G ++ W                  PK
Sbjct: 424 DELVPRLIKFFDGPGRGGSQIQCGSSFCMTVNEHGALYFWGQSKPTGEATMY------PK 585

Query: 651 LIEKLQDLDVIKVRCGSQFSIALTKDGQVYSWGKGDNQ-RLGHGTE--EHVRYPKLLEGL 707
           L++ L    V  + C  + SI L  D  V SWG       LG+G    +     + ++ L
Sbjct: 586 LVQDLSGWKVRSIGCCYR-SIVLCADDSVVSWGPSPTYGELGYGENKMKSSTVAQEVKPL 762

Query: 708 QGKKVIDVAAGSTHCLAL----TEDSEVH 732
            G  V DVA G  H L +    TE+ + H
Sbjct: 763 DGVYVHDVACGYAHTLMIARCDTEEEKEH 849

 Score = 55.8 bits (133), Expect = 4e-07,   Method: Compositional matrix adjust.
 Identities = 51/186 (27%), Positives = 78/186 (41%), Gaps = 5/186 (2%)
 Frame = +1

Query: 4036 IQHVFIKKVAVNSGGKHCLALSSEGEVYSWGEAEDGKLGHGNRSPCDRPRVIESLRGIEV 4095
            I  V I++VA   G  H L + S+  ++SWG    G+LGH        PR+I+   G   
Sbjct: 298  ITDVDIREVAC--GLNHTLIMDSKKRLFSWGFGGYGRLGHAEPKDELVPRLIKFFDGPGR 471

Query: 4096 --VDVAAGGAHSACVTAAGDLYTWGKGRYGRLGHSDSEDQLKPKLVEALQGHRVIDIACG 4153
                +  G +    V   G LY WG+ +         E  + PKLV+ L G +V  I C 
Sbjct: 472  GGSQIQCGSSFCMTVNEHGALYFWGQSK------PTGEATMYPKLVQDLSGWKVRSIGCC 633

Query: 4154 SGDAQTLCLTDDDTVWSWXXXXXXXXXXXXXXXCK---VPMKIDSLTGLGVVKVECGSQF 4210
                +++ L  DD+V SW                K   V  ++  L G+ V  V CG   
Sbjct: 634  ---YRSIVLCADDSVVSWGPSPTYGELGYGENKMKSSTVAQEVKPLDGVYVHDVACGYAH 804

Query: 4211 SVALTK 4216
            ++ + +
Sbjct: 805  TLMIAR 822

 Score = 53.1 bits (126), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 45/176 (25%), Positives = 71/176 (40%), Gaps = 5/176 (2%)
 Frame = +1

Query: 3053 VHSGGRHATALTVDGKVFSWGEGDDGKLGHFSRMNCDKPRLIEALK--TKRIRDIACGSS 3110
            V  G  H   +    ++FSWG G  G+LGH    +   PRLI+      +    I CGSS
Sbjct: 322  VACGLNHTLIMDSKKRLFSWGFGGYGRLGHAEPKDELVPRLIKFFDGPGRGGSQIQCGSS 501

Query: 3111 HSAALTSSGELYTWGLGEYGRLGHGDNTTQLKPKMVKVLLGHRVIQVACGSRDAQTLALT 3170
                +   G LY WG  +            + PK+V+ L G +V  + C  R   ++ L 
Sbjct: 502  FCMTVNEHGALYFWGQSK------PTGEATMYPKLVQDLSGWKVRSIGCCYR---SIVLC 654

Query: 3171 DEGLVFSWX---XXXXXXXXXXXSEGCNIPQNIERLNGQGVCQIECGAQFSLALTK 3223
             +  V SW                +   + Q ++ L+G  V  + CG   +L + +
Sbjct: 655  ADDSVVSWGPSPTYGELGYGENKMKSSTVAQEVKPLDGVYVHDVACGYAHTLMIAR 822

 Score = 52.0 bits (123), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 60/261 (22%), Positives = 99/261 (37%), Gaps = 29/261 (11%)
 Frame = +1

Query: 549 QAGKHVVHIACGSTYSAAITAEGELYTWGRGNYGRLGHGSS------------EDEAIPM 596
           Q   H  H   G  +S      G LY++G   YG+LGH S             + E  P 
Sbjct: 73  QGPPHQTHRVRGE-FSTMSDINGNLYSFGCPEYGQLGHNSDGKYFVTSNKMEYKCEMTPR 249

Query: 597 LVA------------GLKGLKVIDVACGSGDAQTLAVTENGQVWSWXXXXXXXXXXXXXX 644
            V+             +  + + +VACG     TL +    +++SW              
Sbjct: 250 KVSVFIEKTRDGHVMPITDVDIREVACGLN--HTLIMDSKKRLFSWGFGGYGRLGHAEPK 423

Query: 645 XCKTPKLIEKLQ--DLDVIKVRCGSQFSIALTKDGQVYSWGKGDNQRLGHGTEEHVRYPK 702
               P+LI+          +++CGS F + + + G +Y WG+         T E   YPK
Sbjct: 424 DELVPRLIKFFDGPGRGGSQIQCGSSFCMTVNEHGALYFWGQSKP------TGEATMYPK 585

Query: 703 LLEGLQGKKVIDVAAGSTHCLALTEDSEVHSWG---SNDQCQHFDTLRVTKPEPTALPGL 759
           L++ L G KV  +       + L  D  V SWG   +  +  + +    +      +  L
Sbjct: 586 LVQDLSGWKVRSIGC-CYRSIVLCADDSVVSWGPSPTYGELGYGENKMKSSTVAQEVKPL 762

Query: 760 DSKHIVGIACGPAQSFAWSSC 780
           D  ++  +ACG A +   + C
Sbjct: 763 DGVYVHDVACGYAHTLMIARC 825
>13725
          Length = 700

 Score = 63.9 bits (154), Expect = 2e-09,   Method: Composition-based stats.
 Identities = 56/180 (31%), Positives = 81/180 (45%), Gaps = 8/180 (4%)
 Frame = +2

Query: 4470 VKFVGESVDDCGGGYSESIAEICEELQNGLTPLLIVTPNGRDESGANRDCYLL--NPATR 4527
            VKF GE   D GG   E    +  E+ N    L            +  D Y L  NP + 
Sbjct: 143  VKFHGEEGLDYGGVAREWFYLLSHEMLNPYYGLF---------QYSREDIYTLQINPDSG 295

Query: 4528 A-PVHCSMFRFLGVLLGIAIRTGSPLSLNLAEPVWKQLAGMSLTIADLSEVDKDFIPGLM 4586
              P H S F F+G ++G+AI  G  L      P +KQL G   T+ DL  VD D    L 
Sbjct: 296  VNPEHLSYFHFVGRVIGMAIFHGHYLDGGFTMPFYKQLLGKPATLEDLESVDPDLHRSLC 475

Query: 4587 YIRDNEATSEEFEAMSLPFTVPSAS-GQ----DIQLSSKHTHITLDNRAEYVRLAINYRL 4641
            ++ +N   +     +   F+V   S G+    +++     T +T DN+ EYVRL +++RL
Sbjct: 476  WMLENNIEN----VLEHTFSVEHNSFGKLREYELKPGGNDTKVTEDNKHEYVRLYVHWRL 643
>38263
          Length = 368

 Score = 53.5 bits (127), Expect = 2e-06,   Method: Composition-based stats.
 Identities = 21/46 (45%), Positives = 26/46 (56%)
 Frame = +2

Query: 2702 SIHPGVTCDGCQTFPINGSRFKCRNCDDFDFCETCFKTKKHNTRHT 2747
            S H GV+CD C      G R+KC  C D+D C TC++     TRHT
Sbjct: 188  SRHEGVSCDSCLKGNFRGRRYKCLICYDYDLCATCYEAGATTTRHT 325
>03352
          Length = 935

 Score = 50.8 bits (120), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 45/156 (28%), Positives = 71/156 (45%), Gaps = 6/156 (3%)
 Frame = +2

Query: 3153 RVIQVACGSRDAQTLALTDEGLV-FSWXXXXXXXXXXXXSEGCNIPQNIE-----RLNGQ 3206
            ++ QVA G   A  L L D+G V F              ++G   P++++     R+  +
Sbjct: 35   KIQQVATGHEGAHALMLADDGSVFFVGLAKRGEDGDSGAAKGRRQPKSVKPKKMIRVENK 214

Query: 3207 GVCQIECGAQFSLALTKSGVVWTWGKGDYFRLGHGSDVHVRKPQVVEGLRGKKIVHVAVG 3266
             V  + C +  S  +TK G V+ +GK D     H S  HV        L+   +  VA+G
Sbjct: 215  QVVFVACNSGSSAVVTKDGEVYMFGK-DTSHCDHASG-HVTD------LKDVVVTQVALG 370

Query: 3267 ALHCLAVTDSGQVYAWGDNDHGQQGNGTTTVNRKPT 3302
              H +A+T  GQ++ +G N+ GQ G   T V  + T
Sbjct: 371  KAHTVALTSKGQLFTFGINNKGQCGRDFTQVGVRET 478

 Score = 49.3 bits (116), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 42/137 (30%), Positives = 66/137 (48%), Gaps = 6/137 (4%)
 Frame = +2

Query: 3048 VKKVAVHSGGRHATALTVDGKVFSWG------EGDDGKLGHFSRMNCDKPRLIEALKTKR 3101
            +++VA    G HA  L  DG VF  G      +GD G      +    KP+ +  ++ K+
Sbjct: 38   IQQVATGHEGAHALMLADDGSVFFVGLAKRGEDGDSGAAKGRRQPKSVKPKKMIRVENKQ 217

Query: 3102 IRDIACGSSHSAALTSSGELYTWGLGEYGRLGHGDNTTQLKPKMVKVLLGHRVIQVACGS 3161
            +  +AC S  SA +T  GE+Y +G        H D+ +     +  V+    V QVA G 
Sbjct: 218  VVFVACNSGSSAVVTKDGEVYMFGK----DTSHCDHASGHVTDLKDVV----VTQVALGK 373

Query: 3162 RDAQTLALTDEGLVFSW 3178
              A T+ALT +G +F++
Sbjct: 374  --AHTVALTSKGQLFTF 418

 Score = 43.5 bits (101), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 29/93 (31%), Positives = 48/93 (51%)
 Frame = +2

Query: 649 PKLIEKLQDLDVIKVRCGSQFSIALTKDGQVYSWGKGDNQRLGHGTEEHVRYPKLLEGLQ 708
           PK + ++++  V+ V C S  S  +TKDG+VY +GK D     H +         +  L+
Sbjct: 185 PKKMIRVENKQVVFVACNSGSSAVVTKDGEVYMFGK-DTSHCDHASGH-------VTDLK 340

Query: 709 GKKVIDVAAGSTHCLALTEDSEVHSWGSNDQCQ 741
              V  VA G  H +ALT   ++ ++G N++ Q
Sbjct: 341 DVVVTQVALGKAHTVALTSKGQLFTFGINNKGQ 439

 Score = 42.4 bits (98), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 40/140 (28%), Positives = 61/140 (43%), Gaps = 2/140 (1%)
 Frame = +2

Query: 493 SRNIVKIAAHSDGHHYLALAATGEVYSWXXXXXXXXXXXDTVP-LEEPKVISAFSG-KQA 550
           S  I ++A   +G H L LA  G V+                    +PK +      +  
Sbjct: 29  SPKIQQVATGHEGAHALMLADDGSVFFVGLAKRGEDGDSGAAKGRRQPKSVKPKKMIRVE 208

Query: 551 GKHVVHIACGSTYSAAITAEGELYTWGRGNYGRLGHGSSEDEAIPMLVAGLKGLKVIDVA 610
            K VV +AC S  SA +T +GE+Y +G+ +     H S         V  LK + V  VA
Sbjct: 209 NKQVVFVACNSGSSAVVTKDGEVYMFGK-DTSHCDHASGH-------VTDLKDVVVTQVA 364

Query: 611 CGSGDAQTLAVTENGQVWSW 630
            G   A T+A+T  GQ++++
Sbjct: 365 LGK--AHTVALTSKGQLFTF 418

 Score = 35.4 bits (80), Expect = 0.63,   Method: Compositional matrix adjust.
 Identities = 32/114 (28%), Positives = 51/114 (44%)
 Frame = +2

Query: 4207 GSQFSVALTKSGAVYTWGKGDYHRLGHGSDDHVRRPRQVQGLQGKKVIAIATGSLHCVCC 4266
            GS F V L K G     G     R          +P+++  ++ K+V+ +A  S      
Sbjct: 95   GSVFFVGLAKRGEDGDSGAAKGRR-----QPKSVKPKKMIRVENKQVVFVACNSGSSAVV 259

Query: 4267 TEDGEVYTWGDNDEGQLGDGTTNAIQRPRLVAALQGKKVNRVACGSAHTLAWST 4320
            T+DGEVY +G +        T++       V  L+   V +VA G AHT+A ++
Sbjct: 260  TKDGEVYMFGKD--------TSHCDHASGHVTDLKDVVVTQVALGKAHTVALTS 397

 Score = 32.7 bits (73), Expect = 3.2,   Method: Compositional matrix adjust.
 Identities = 25/81 (30%), Positives = 40/81 (49%), Gaps = 1/81 (1%)
 Frame = +2

Query: 3248 KPQVVEGLRGKKIVHVAVGALHCLAVTDSGQVYAWG-DNDHGQQGNGTTTVNRKPTLVQG 3306
            KP+ +  +  K++V VA  +     VT  G+VY +G D  H    +G  T          
Sbjct: 182  KPKKMIRVENKQVVFVACNSGSSAVVTKDGEVYMFGKDTSHCDHASGHVT---------D 334

Query: 3307 LEGQKITRVACGSSHSVAWTT 3327
            L+   +T+VA G +H+VA T+
Sbjct: 335  LKDVVVTQVALGKAHTVALTS 397

 Score = 32.7 bits (73), Expect = 3.5,   Method: Compositional matrix adjust.
 Identities = 33/146 (22%), Positives = 60/146 (41%), Gaps = 6/146 (4%)
 Frame = +2

Query: 4093 IEVVDVAAGGAHSACVTAAGDLYTWGKGRYGRLGHSDSED------QLKPKLVEALQGHR 4146
            I+ V     GAH+  +   G ++  G  + G  G S +         +KPK +  ++  +
Sbjct: 38   IQQVATGHEGAHALMLADDGSVFFVGLAKRGEDGDSGAAKGRRQPKSVKPKKMIRVENKQ 217

Query: 4147 VIDIACGSGDAQTLCLTDDDTVWSWXXXXXXXXXXXXXXXCKVPMKIDSLTGLGVVKVEC 4206
            V+ +AC SG +    +T D  V+ +                     +  L  + V +V  
Sbjct: 218  VVFVACNSGSSAV--VTKDGEVYMFGKDTSHCDHASG--------HVTDLKDVVVTQVAL 367

Query: 4207 GSQFSVALTKSGAVYTWGKGDYHRLG 4232
            G   +VALT  G ++T+G  +  + G
Sbjct: 368  GKAHTVALTSKGQLFTFGINNKGQCG 445
>19738
          Length = 375

 Score = 41.2 bits (95), Expect(2) = 3e-05,   Method: Composition-based stats.
 Identities = 24/67 (35%), Positives = 41/67 (61%)
 Frame = +2

Query: 4612 GQDIQLSSKHTHITLDNRAEYVRLAINYRLHEFDEQVAAVREGMARVVPVPLLSLFTGYE 4671
            G +I++++K+    LD  A+Y RLA + +     E+V +   G+  ++P  LLS+F  YE
Sbjct: 23   GGNIRVTNKNKLSYLDCLAQY-RLATSVK-----EEVESFLRGLNELIPDNLLSIFDEYE 184

Query: 4672 LETMVCG 4678
            LE ++CG
Sbjct: 185  LELLMCG 205

 Score = 27.7 bits (60), Expect(2) = 3e-05,   Method: Compositional matrix adjust.
 Identities = 11/31 (35%), Positives = 20/31 (64%)
 Frame = +1

Query: 4702 LVQWFWEVMESFSNTERSLFLRFVWGRTRLP 4732
            ++ WFW V+ SF+  + +  L+F  G ++LP
Sbjct: 277  VLDWFWTVIASFTEEQMARLLQFTTGCSQLP 369
>39525
          Length = 450

 Score = 49.7 bits (117), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 23/45 (51%), Positives = 33/45 (73%), Gaps = 2/45 (4%)
 Frame = -3

Query: 4242 PRQVQGLQGKKVIAIATG--SLHCVCCTEDGEVYTWGDNDEGQLG 4284
            P ++  L+G KV  IA+G  + HCV  T++G+VYTWG N++GQLG
Sbjct: 193  PHRMAALEGIKVRTIASGCNACHCVAITDEGKVYTWGRNEKGQLG 59

 Score = 45.1 bits (105), Expect = 6e-04,   Method: Compositional matrix adjust.
 Identities = 23/55 (41%), Positives = 30/55 (54%), Gaps = 2/55 (3%)
 Frame = -3

Query: 3249 PQVVEGLRGKKIVHVAVG--ALHCLAVTDSGQVYAWGDNDHGQQGNGTTTVNRKP 3301
            P  +  L G K+  +A G  A HC+A+TD G+VY WG N+ GQ G   T     P
Sbjct: 193  PHRMAALEGIKVRTIASGCNACHCVAITDEGKVYTWGRNEKGQLGLSDTVRRDAP 29

 Score = 42.4 bits (98), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 15/46 (32%), Positives = 30/46 (65%)
 Frame = -3

Query: 4029 TPTLLESIQHVFIKKVAVNSGGKHCLALSSEGEVYSWGEAEDGKLG 4074
            +P  + +++ + ++ +A      HC+A++ EG+VY+WG  E G+LG
Sbjct: 196  SPHRMAALEGIKVRTIASGCNACHCVAITDEGKVYTWGRNEKGQLG 59

 Score = 42.0 bits (97), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 21/55 (38%), Positives = 31/55 (56%), Gaps = 2/55 (3%)
 Frame = -3

Query: 3091 PRLIEALKTKRIRDIA--CGSSHSAALTSSGELYTWGLGEYGRLGHGDNTTQLKP 3143
            P  + AL+  ++R IA  C + H  A+T  G++YTWG  E G+LG  D   +  P
Sbjct: 193  PHRMAALEGIKVRTIASGCNACHCVAITDEGKVYTWGRNEKGQLGLSDTVRRDAP 29

 Score = 38.9 bits (89), Expect = 0.054,   Method: Compositional matrix adjust.
 Identities = 20/55 (36%), Positives = 35/55 (63%), Gaps = 4/55 (7%)
 Frame = -3

Query: 701 PKLLEGLQGKKVIDVAAG--STHCLALTEDSEVHSWGSNDQCQ--HFDTLRVTKP 751
           P  +  L+G KV  +A+G  + HC+A+T++ +V++WG N++ Q    DT+R   P
Sbjct: 193 PHRMAALEGIKVRTIASGCNACHCVAITDEGKVYTWGRNEKGQLGLSDTVRRDAP 29

 Score = 38.5 bits (88), Expect = 0.063,   Method: Compositional matrix adjust.
 Identities = 19/49 (38%), Positives = 29/49 (59%), Gaps = 2/49 (4%)
 Frame = -3

Query: 4084 PRVIESLRGIEVVDVAAG--GAHSACVTAAGDLYTWGKGRYGRLGHSDS 4130
            P  + +L GI+V  +A+G    H   +T  G +YTWG+   G+LG SD+
Sbjct: 193  PHRMAALEGIKVRTIASGCNACHCVAITDEGKVYTWGRNEKGQLGLSDT 47

 Score = 37.7 bits (86), Expect = 0.11,   Method: Compositional matrix adjust.
 Identities = 18/55 (32%), Positives = 29/55 (52%)
 Frame = -3

Query: 3037 PRQITALSSYVVKKVAVHSGGRHATALTVDGKVFSWGEGDDGKLGHFSRMNCDKP 3091
            P ++ AL    V+ +A      H  A+T +GKV++WG  + G+LG    +  D P
Sbjct: 193  PHRMAALEGIKVRTIASGCNACHCVAITDEGKVYTWGRNEKGQLGLSDTVRRDAP 29

 Score = 37.0 bits (84), Expect = 0.17,   Method: Compositional matrix adjust.
 Identities = 18/50 (36%), Positives = 27/50 (54%)
 Frame = -3

Query: 536 LEEPKVISAFSGKQAGKHVVHIACGSTYSAAITAEGELYTWGRGNYGRLG 585
           L  P  ++A  G +     +   C + +  AIT EG++YTWGR   G+LG
Sbjct: 202 LWSPHRMAALEGIKV--RTIASGCNACHCVAITDEGKVYTWGRNEKGQLG 59

 Score = 33.5 bits (75), Expect = 2.0,   Method: Compositional matrix adjust.
 Identities = 20/54 (37%), Positives = 30/54 (55%), Gaps = 2/54 (3%)
 Frame = -3

Query: 4190 PMKIDSLTGLGVVKVE--CGSQFSVALTKSGAVYTWGKGDYHRLGHGSDDHVRR 4241
            P ++ +L G+ V  +   C +   VA+T  G VYTWG+ +  +LG    D VRR
Sbjct: 193  PHRMAALEGIKVRTIASGCNACHCVAITDEGKVYTWGRNEKGQLGLS--DTVRR 38
>12101
          Length = 1020

 Score = 49.3 bits (116), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 24/62 (38%), Positives = 38/62 (61%)
 Frame = -2

Query: 538 EPKVISAFSGKQAGKHVVHIACGSTYSAAITAEGELYTWGRGNYGRLGHGSSEDEAIPML 597
           +P  I+  +GK     V ++ACG   S  IT +G+LY+WG G+  +LG G  +DE +P+ 
Sbjct: 644 KPTAITQLNGK-----VNYVACGEACSFXITNDGKLYSWGMGSLLQLGVGDGDDEVVPVE 480

Query: 598 VA 599
           V+
Sbjct: 479 VS 474

 Score = 47.4 bits (111), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 42/133 (31%), Positives = 63/133 (47%), Gaps = 15/133 (11%)
 Frame = -2

Query: 3048 VKKVAVHSGGRHAT-ALTVDGKVFSWGEGDDGKLGHFSRMNC-DKPRLIEALKTKRIRDI 3105
            +K V   +GG+H T  L  + +  + G  + G+LG         KP  I  L  K +  +
Sbjct: 776  IKDVKQIAGGQHHTLILDNNMRCLAVGRPEYGRLGLGKVTEVVTKPTAITQLNGK-VNYV 600

Query: 3106 ACGSSHSAALTSSGELYTWGLGEYGRLGHGDNTTQLKPKMV--------KVLLG-----H 3152
            ACG + S  +T+ G+LY+WG+G   +LG GD   ++ P  V        KVLL      H
Sbjct: 599  ACGEACSFXITNDGKLYSWGMGSLLQLGVGDGDDEVVPVEVSSKNTQNKKVLLADGGGQH 420

Query: 3153 RVIQVACGSRDAQ 3165
             V  V    ++AQ
Sbjct: 419  SVFLVEADVQEAQ 381

 Score = 43.9 bits (102), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 46/149 (30%), Positives = 65/149 (43%), Gaps = 11/149 (7%)
 Frame = -2

Query: 2944 LIRKKTPGLESTATIRTKVF--------VW--GLNDKDQLGGLKGS-KIKVPSFSETLSA 2992
            LI K+T  +ES        F        +W  GLN+  QL   K + +   P  +E    
Sbjct: 944  LIIKRTKPIESIWATNYCTFMRESQTQTIWAVGLNNYKQLAHPKETERFLTPVKTEIK-- 771

Query: 2993 LNVVQVAGGSKSLFAVTVEGKVYSCGEATNGRLGLGMSSGTVPIPRQITALSSYVVKKVA 3052
             +V Q+AGG      +    +  + G    GRLGLG  +  V  P  IT L+  V     
Sbjct: 770  -DVKQIAGGQHHTLILDNNMRCLAVGRPEYGRLGLGKVTEVVTKPTAITQLNGKV---NY 603

Query: 3053 VHSGGRHATALTVDGKVFSWGEGDDGKLG 3081
            V  G   +  +T DGK++SWG G   +LG
Sbjct: 602  VACGEACSFXITNDGKLYSWGMGSLLQLG 516

 Score = 41.6 bits (96), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 29/81 (35%), Positives = 36/81 (44%), Gaps = 2/81 (2%)
 Frame = -2

Query: 4190 PMKIDSLTGLGVVKVECGSQFSVALTKSGAVYTWGKGDYHRLGHGSDDHVRRPRQV--QG 4247
            P  I  L G  V  V CG   S  +T  G +Y+WG G   +LG G  D    P +V  + 
Sbjct: 641  PTAITQLNGK-VNYVACGEACSFXITNDGKLYSWGMGSLLQLGVGDGDDEVVPVEVSSKN 465

Query: 4248 LQGKKVIAIATGSLHCVCCTE 4268
             Q KKV+    G  H V   E
Sbjct: 464  TQNKKVLLADGGGQHSVFLVE 402

 Score = 40.4 bits (93), Expect = 0.018,   Method: Compositional matrix adjust.
 Identities = 25/67 (37%), Positives = 33/67 (49%), Gaps = 2/67 (2%)
 Frame = -2

Query: 663 VRCGSQFSIALTKDGQVYSWGKGDNQRL--GHGTEEHVRYPKLLEGLQGKKVIDVAAGST 720
           V CG   S  +T DG++YSWG G   +L  G G +E V      +  Q KKV+    G  
Sbjct: 602 VACGEACSFXITNDGKLYSWGMGSLLQLGVGDGDDEVVPVEVSSKNTQNKKVLLADGGGQ 423

Query: 721 HCLALTE 727
           H + L E
Sbjct: 422 HSVFLVE 402

 Score = 38.5 bits (88), Expect = 0.071,   Method: Compositional matrix adjust.
 Identities = 28/80 (35%), Positives = 40/80 (50%), Gaps = 1/80 (1%)
 Frame = -2

Query: 552 KHVVHIACGSTYSAAITAEGELYTWGRGNYGRLGHGS-SEDEAIPMLVAGLKGLKVIDVA 610
           K V  IA G  ++  +         GR  YGRLG G  +E    P  +  L G KV  VA
Sbjct: 773 KDVKQIAGGQHHTLILDNNMRCLAVGRPEYGRLGLGKVTEVVTKPTAITQLNG-KVNYVA 597

Query: 611 CGSGDAQTLAVTENGQVWSW 630
           C  G+A +  +T +G+++SW
Sbjct: 596 C--GEACSFXITNDGKLYSW 543

 Score = 37.7 bits (86), Expect = 0.10,   Method: Compositional matrix adjust.
 Identities = 35/119 (29%), Positives = 54/119 (45%), Gaps = 3/119 (2%)
 Frame = -2

Query: 4201 VVKVECGSQFSVALTKSGAVYTWGKGDYHRLGHGS-DDHVRRPRQVQGLQGKKVIAIATG 4259
            V ++  G   ++ L  +      G+ +Y RLG G   + V +P  +  L GK V  +A G
Sbjct: 767  VKQIAGGQHHTLILDNNMRCLAVGRPEYGRLGLGKVTEVVTKPTAITQLNGK-VNYVACG 591

Query: 4260 SLHCVCCTEDGEVYTWGDNDEGQLGDGTTNAIQRPRLVAA--LQGKKVNRVACGSAHTL 4316
                   T DG++Y+WG     QLG G  +    P  V++   Q KKV     G  H++
Sbjct: 590  EACSFXITNDGKLYSWGMGSLLQLGVGDGDDEVVPVEVSSKNTQNKKVLLADGGGQHSV 414

 Score = 35.4 bits (80), Expect = 0.57,   Method: Compositional matrix adjust.
 Identities = 17/45 (37%), Positives = 25/45 (55%)
 Frame = -2

Query: 3197 PQNIERLNGQGVCQIECGAQFSLALTKSGVVWTWGKGDYFRLGHG 3241
            P  I +LNG+ V  + CG   S  +T  G +++WG G   +LG G
Sbjct: 641  PTAITQLNGK-VNYVACGEACSFXITNDGKLYSWGMGSLLQLGVG 510

 Score = 32.3 bits (72), Expect = 4.3,   Method: Compositional matrix adjust.
 Identities = 23/64 (35%), Positives = 30/64 (46%), Gaps = 1/64 (1%)
 Frame = -2

Query: 4251 KKVIAIATGSLHCVCCTEDGEVYTWGDNDEGQLGDG-TTNAIQRPRLVAALQGKKVNRVA 4309
            K V  IA G  H +    +      G  + G+LG G  T  + +P  +  L GK VN VA
Sbjct: 773  KDVKQIAGGQHHTLILDNNMRCLAVGRPEYGRLGLGKVTEVVTKPTAITQLNGK-VNYVA 597

Query: 4310 CGSA 4313
            CG A
Sbjct: 596  CGEA 585

 Score = 32.0 bits (71), Expect = 6.9,   Method: Compositional matrix adjust.
 Identities = 25/88 (28%), Positives = 45/88 (51%), Gaps = 2/88 (2%)
 Frame = -2

Query: 2978 GSKIKVPSFSETLSALN--VVQVAGGSKSLFAVTVEGKVYSCGEATNGRLGLGMSSGTVP 3035
            G   +V +    ++ LN  V  VA G    F +T +GK+YS G  +  +LG+G     V 
Sbjct: 668  GKVTEVVTKPTAITQLNGKVNYVACGEACSFXITNDGKLYSWGMGSLLQLGVGDGDDEV- 492

Query: 3036 IPRQITALSSYVVKKVAVHSGGRHATAL 3063
            +P ++++ ++   K +    GG+H+  L
Sbjct: 491  VPVEVSSKNTQNKKVLLADGGGQHSVFL 408
>33425
          Length = 477

 Score = 47.8 bits (112), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 23/53 (43%), Positives = 32/53 (60%), Gaps = 2/53 (3%)
 Frame = -3

Query: 3278 QVYAWGDNDHGQQGNGTTTVNRKPTLVQ--GLEGQKITRVACGSSHSVAWTTV 3328
            +VYAWG+N  GQ G G+      P   +  GLEG  + ++A G+SHSV WT +
Sbjct: 466  EVYAWGNNAMGQCGQGSLPEPHLPPTARWWGLEGVPVQQIAAGTSHSVVWTAM 308

 Score = 42.4 bits (98), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 19/54 (35%), Positives = 29/54 (53%), Gaps = 2/54 (3%)
 Frame = -3

Query: 4268 EDGEVYTWGDNDEGQLGDGTTNAIQRPRLVA--ALQGKKVNRVACGSAHTLAWS 4319
             D EVY WG+N  GQ G G+      P       L+G  V ++A G++H++ W+
Sbjct: 475  HDNEVYAWGNNAMGQCGQGSLPEPHLPPTARWWGLEGVPVQQIAAGTSHSVVWT 314

 Score = 38.1 bits (87), Expect = 0.076,   Method: Compositional matrix adjust.
 Identities = 33/106 (31%), Positives = 47/106 (44%), Gaps = 9/106 (8%)
 Frame = -3

Query: 727 EDSEVHSWGSN--DQCQHFDTLRVTKPEPTALP-----GLDSKHIVGIACGPAQSFAWSS 779
            D+EV++WG+N   QC      + + PEP   P     GL+   +  IA G + S  W++
Sbjct: 475 HDNEVYAWGNNAMGQCG-----QGSLPEPHLPPTARWWGLEGVPVQQIAAGTSHSVVWTA 311

Query: 780 --CSEWSIGLRVPFVVDICSMTFEQLDLLLRQVSEGMDGTADWPPP 823
                  I    PF VD+   TF  L   L +  +G     D PPP
Sbjct: 310 MPSDRHVIAWHRPFCVDLQEATFASLCSFLERYCDGFYA-EDPPPP 176

 Score = 35.8 bits (81), Expect = 0.43,   Method: Compositional matrix adjust.
 Identities = 21/65 (32%), Positives = 33/65 (50%), Gaps = 5/65 (7%)
 Frame = -3

Query: 675 KDGQVYSWGKGDNQRLGHGT--EEHVRYPKLLEGLQGKKVIDVAAGSTHCL---ALTEDS 729
            D +VY+WG     + G G+  E H+       GL+G  V  +AAG++H +   A+  D 
Sbjct: 475 HDNEVYAWGNNAMGQCGQGSLPEPHLPPTARWWGLEGVPVQQIAAGTSHSVVWTAMPSDR 296

Query: 730 EVHSW 734
            V +W
Sbjct: 295 HVIAW 281

 Score = 33.5 bits (75), Expect = 2.3,   Method: Compositional matrix adjust.
 Identities = 19/54 (35%), Positives = 26/54 (48%), Gaps = 2/54 (3%)
 Frame = -3

Query: 4059 EGEVYSWGEAEDGKLGHGNRSPCDRPRVIE--SLRGIEVVDVAAGGAHSACVTA 4110
            + EVY+WG    G+ G G+      P       L G+ V  +AAG +HS   TA
Sbjct: 472  DNEVYAWGNNAMGQCGQGSLPEPHLPPTARWWGLEGVPVQQIAAGTSHSVVWTA 311
>14299
          Length = 716

 Score = 47.4 bits (111), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 21/46 (45%), Positives = 26/46 (56%)
 Frame = +3

Query: 2702 SIHPGVTCDGCQTFPINGSRFKCRNCDDFDFCETCFKTKKHNTRHT 2747
            S H GV+CD C      G R+KC  C D+D C TC++     TRHT
Sbjct: 249  SRHEGVSCDSCLKGNFRGRRYKCLICYDYDLCATCYEAGATTTRHT 386
>07471
          Length = 1673

 Score = 44.3 bits (103), Expect = 0.001,   Method: Composition-based stats.
 Identities = 28/97 (28%), Positives = 44/97 (45%), Gaps = 4/97 (4%)
 Frame = -3

Query: 2662 VTHQSVGLVKAFS--ANGKDIIVDFPQQSHWTGLLSEMELVPSIHPGVTCDGCQTFPING 2719
            V  ++   VK+FS  ++G D     P  S   G+         +H  + CD C    I G
Sbjct: 1554 VAKKTAKYVKSFSKKSDGSDGQDSQPSVSSKXGV---------VHEDIICDCCNG-EIVG 1405

Query: 2720 SRFKCRNCDDFDFCETC--FKTKKHNTRHTFGRINEP 2754
            +R+ C NC ++D CE C   +   H+  H F ++  P
Sbjct: 1404 TRYICGNCPNYDLCEACENIQPSFHDRSHVFIKLRRP 1294
>01993
          Length = 1915

 Score = 37.4 bits (85), Expect = 0.14,   Method: Composition-based stats.
 Identities = 25/95 (26%), Positives = 38/95 (40%)
 Frame = -2

Query: 1179 KERDDHEELAWPGIMESFFTGQNCRNNEEVTLIRKADLENHNKDGGFWTVIDGKVYGIKD 1238
            KER   +  A   IM S           EV + R  +++ H      W +ID KVY +  
Sbjct: 1857 KERSQKQREAATRIMAS---------KVEVKVYRAEEVKQHKDSKSTWFIIDNKVYDVTK 1705

Query: 1239 FQTQSLTGNSILAQFAGEDPVVALEAALQFEDTQE 1273
            F  +   G  ++ + AG D   A E      D ++
Sbjct: 1704 FLDEHPGGEEVMLEQAGGDATQAFEDVGHSSDARD 1600
>01451
          Length = 1229

 Score = 37.0 bits (84), Expect = 0.18,   Method: Compositional matrix adjust.
 Identities = 17/32 (53%), Positives = 23/32 (71%)
 Frame = -3

Query: 4253 VIAIATGSLHCVCCTEDGEVYTWGDNDEGQLG 4284
            V+ IA+GS H  C T+ GE+YT G  ++GQLG
Sbjct: 1155 VVKIASGSDHIACLTDLGELYTLGCAEQGQLG 1060

 Score = 35.8 bits (81), Expect = 0.42,   Method: Compositional matrix adjust.
 Identities = 19/40 (47%), Positives = 24/40 (60%)
 Frame = -3

Query: 4087 IESLRGIEVVDVAAGGAHSACVTAAGDLYTWGKGRYGRLG 4126
            IE L    VV +A+G  H AC+T  G+LYT G    G+LG
Sbjct: 1179 IEVLPDAVVVKIASGSDHIACLTDLGELYTLGCAEQGQLG 1060
>11020
          Length = 910

 Score = 35.0 bits (79), Expect = 0.69,   Method: Composition-based stats.
 Identities = 20/50 (40%), Positives = 31/50 (62%), Gaps = 4/50 (8%)
 Frame = +3

Query: 1885 QDGPPPGLG---RVIGELGEDGWIRVQWDTGST-NSYRMGKEGKYDLKLV 1930
            +DG PPGLG   RV  +L  D ++ V+WD G+  ++  MG +  Y+L+ V
Sbjct: 621  KDGSPPGLGTVTRVNDDLTTD-FVAVKWDCGNYHDNIYMGFDNTYELRFV 767
>31200
          Length = 445

 Score = 34.7 bits (78), Expect = 1.0,   Method: Compositional matrix adjust.
 Identities = 27/107 (25%), Positives = 47/107 (43%), Gaps = 2/107 (1%)
 Frame = +3

Query: 579 GNYGRLGHGSSEDEAIPMLVA--GLKGLKVIDVACGSGDAQTLAVTENGQVWSWXXXXXX 636
           G +GRLGH   +DE +P L+     +G     V CGS    +L + E G ++ +      
Sbjct: 6   GGFGRLGHAEPKDEMVPRLMKFYDTQGRGGRSVYCGS--TFSLIINELGLLYLFGQNKKT 179

Query: 637 XXXXXXXXXCKTPKLIEKLQDLDVIKVRCGSQFSIALTKDGQVYSWG 683
                       PK ++ L   ++  + C +  SI ++ D  + +WG
Sbjct: 180 GEANMY------PKPVQDLSGWNITSIGCANT-SIMISADDTLIAWG 299

 Score = 33.5 bits (75), Expect = 1.9,   Method: Compositional matrix adjust.
 Identities = 33/134 (24%), Positives = 57/134 (42%), Gaps = 2/134 (1%)
 Frame = +3

Query: 3126 LGEYGRLGHGDNTTQLKPKMVKVL--LGHRVIQVACGSRDAQTLALTDEGLVFSWXXXXX 3183
             G +GRLGH +   ++ P+++K     G     V CGS    +L + + GL++       
Sbjct: 3    FGGFGRLGHAEPKDEMVPRLMKFYDTQGRGGRSVYCGS--TFSLIINELGLLY------L 158

Query: 3184 XXXXXXXSEGCNIPQNIERLNGQGVCQIECGAQFSLALTKSGVVWTWGKGDYFRLGHGSD 3243
                    E    P+ ++ L+G  +  I C A  S+ ++    +  WG    F    G  
Sbjct: 159  FGQNKKTGEANMYPKPVQDLSGWNITSIGC-ANTSIMISADDTLIAWGASPTFW*AWGIG 335

Query: 3244 VHVRKPQVVEGLRG 3257
                 P+VV+G +G
Sbjct: 336  ---*VPEVVDGAQG 368
>37466
          Length = 593

 Score = 33.9 bits (76), Expect = 1.5,   Method: Composition-based stats.
 Identities = 12/37 (32%), Positives = 20/37 (54%)
 Frame = -3

Query: 2709 CDGCQTFPINGSRFKCRNCDDFDFCETCFKTKKHNTR 2745
            C+ C+      +R+ C  C+DFD C +C+K   H  +
Sbjct: 498  CNNCKAHV--ETRYHCVVCEDFDLCVSCYKRDGHQHK 394
>13682
          Length = 639

 Score = 33.5 bits (75), Expect = 2.2,   Method: Composition-based stats.
 Identities = 18/43 (41%), Positives = 25/43 (58%)
 Frame = -2

Query: 2122 STLRKRRARPQASLTATHSSTLAEEVVGLLRTLHSLTQWNGLI 2164
            STL  R  +P  SL  THS  LA  V+  L +LHS + ++ L+
Sbjct: 500  STLAFRIPKPTVSLLQTHSKRLATLVIASLPSLHSTSTFSSLL 372
>03889
          Length = 1343

 Score = 33.1 bits (74), Expect = 2.9,   Method: Composition-based stats.
 Identities = 13/34 (38%), Positives = 19/34 (55%)
 Frame = -2

Query: 442 GPIQCEGLASLGVMQVACAEKRFLILSRNGRVYT 475
           GP+QC     L V+   C E  F++L  N ++YT
Sbjct: 847 GPVQCSKWPPLLVISFLCFEVDFIVLVHNNKIYT 746
>31463
          Length = 495

 Score = 32.3 bits (72), Expect = 4.4,   Method: Composition-based stats.
 Identities = 15/30 (50%), Positives = 19/30 (63%)
 Frame = +1

Query: 4758 LPESYTCFFLLKLPRYSCKQVLEEKLKYAI 4787
            LP + TC  LLKLP +  ++ L  KL YAI
Sbjct: 22   LPTASTCMNLLKLPEFKDEKTLRTKLLYAI 111
>08616
          Length = 2833

 Score = 31.6 bits (70), Expect = 8.7,   Method: Composition-based stats.
 Identities = 17/55 (30%), Positives = 29/55 (52%), Gaps = 1/55 (1%)
 Frame = -3

Query: 647  KTPKLIEKLQDLDVIKVRCGSQFSIALTKDGQVYS-WGKGDNQRLGHGTEEHVRY 700
            K+PK ++K QD   +K RC S  +  L     ++S + K  + ++ HG   H R+
Sbjct: 2327 KSPKQVKKSQDK*SVKTRCSSGTNTTLRAAMSLFSIYHKDQSFQILHGRRRHARF 2163
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|94369706|ref|XP_131051.5| PREDICTED: sorting nexin
family member 27 [Mus musculus]
         (530 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

07991                                                                 455   e-128
03831                                                                  58   1e-08
20073                                                                  52   8e-07
08480                                                                  39   0.004
38751                                                                  37   0.019
12345                                                                  34   0.14 
01502                                                                  33   0.24 
02951                                                                  33   0.32 
29705                                                                  31   1.3  
05997                                                                  30   3.3  
18014                                                                  29   6.1  
>07991
          Length = 1800

 Score =  455 bits (1171), Expect = e-128,   Method: Compositional matrix adjust.
 Identities = 207/381 (54%), Positives = 286/381 (75%)
 Frame = +3

Query: 141 LDPSDDSLGQSFYDYTEKQAVPISVPTYKHVEQNGEKFVVYNVYMAGRQLCSKRYREFAI 200
           L+PSDDS G S+ DY+E++++PISVP Y++++   +KFVV+N+YMAGR LCS+RYREF  
Sbjct: 84  LEPSDDSSGPSYIDYSERRSLPISVPDYQNMDSGADKFVVFNIYMAGRHLCSRRYREFDN 263

Query: 201 LHQNLKREFANFTFPRLPGKWPFSLSEQQLDARRRGLEEYLEKVCSIRVIGESDIMQEFL 260
           LHQNLKREF +FTFP+LPGK  F LSEQQLD RRRGLE+YLEKVC++RVIGESD+MQ+FL
Sbjct: 264 LHQNLKREFPDFTFPKLPGKKIFHLSEQQLDHRRRGLEQYLEKVCAVRVIGESDVMQDFL 443

Query: 261 SESDENYNGVSDVELRVALPDGTTVTVRVKKNSTTDQVYQAIAAKVGMDSTTVNYFALFE 320
           + +D   +G  +VEL+V LPD     V + ++   D VY+A+A KVG+     +YF LFE
Sbjct: 444 AAADLEDDG--EVELKVLLPDHNICVVTIHRSDNADTVYKAVAXKVGL-GDAADYFYLFE 614

Query: 321 VINHSFVRKLAPNEFPHKLYVQNYTSAVPGTCLTIRKWLFTTEEEVLLNDNDLAVTYFFH 380
            + H+F R+L P+E PH +Y+QNY++A   TCLT+++WLF+ E E  LN N  A+ + F 
Sbjct: 615 TVEHNFERRLQPHELPHNIYIQNYSTAT-ATCLTLKRWLFSLEREATLNSNPQALXFLFG 791

Query: 381 QAVDDVKKGYIKAEEKSYQLQKLHEQRKMVMYLNMLRTCEGYNEIIFPHCACDSRRKGHV 440
           QA +DV +G +K  +K Y+L+ L EQ K++ +L ++R  +GY +++FPHCACDSRR GHV
Sbjct: 792 QAAEDVTRGLLKVGDKLYELKALKEQEKIIEFLKIVRHLDGYGDLMFPHCACDSRRDGHV 971

Query: 441 ITAISITHFKLHACTEEGQLENQVIAFEWDEMQRWDTDEEGMAFCFEYARGEKKPRWVKI 500
           I  IS+  FKL AC E+G  E QVI F W +++ ++ DEEGM+F FEY R  KKPR VKI
Sbjct: 972 IAIISLQSFKLQACKEDGTTEAQVIEFVWKDVKSYEVDEEGMSFNFEYDRPGKKPRVVKI 1151

Query: 501 FTPYFNYMHECFERVFCELKW 521
           FTPYF +M++CF+R++ E++W
Sbjct: 1152FTPYFFFMNDCFDRIYQEMEW 1214

 Score = 35.8 bits (81), Expect = 0.050,   Method: Compositional matrix adjust.
 Identities = 22/53 (41%), Positives = 26/53 (49%)
 Frame = +1

Query: 113 KQVVDLIRAGEKELILTVLSVPPHEADNLDPSDDSLGQSFYDYTEKQAVPISV 165
           KQVVD IR+G   L LTV+SVP           D L  S+     +QA P S 
Sbjct: 1   KQVVDYIRSGGDTLTLTVISVP-----------DQLAASWSRVMTRQAHPTST 126
>03831
          Length = 1143

 Score = 57.8 bits (138), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 35/95 (36%), Positives = 50/95 (52%), Gaps = 2/95 (2%)
 Frame = +3

Query: 39  PRVVRIVKSE--SGYGFNVRGQVSEGGQLRSINGELYAPLQHVSAVLPGGAADRAGVRKG 96
           PR+  IV+    +GYGFN+  +  + GQ              +  V  G  A+ AG++ G
Sbjct: 129 PRLCHIVRWSDFNGYGFNLHAEKGKAGQF-------------IGKVDEGSPAEAAGLKAG 269

Query: 97  DRILEVNGVNVEGATHKQVVDLIRAGEKELILTVL 131
           DRI+EVNG N+    H+QVV  I+AG  E  L V+
Sbjct: 270 DRIVEVNGTNIGNENHQQVVGRIKAGGDETRLLVV 374

 Score = 51.2 bits (121), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 32/95 (33%), Positives = 50/95 (52%), Gaps = 3/95 (3%)
 Frame = +3

Query: 39  PRVVRIVK--SESGYGFNVRGQVSEGGQLRSINGELYAPLQHVSAVLPGGAADRAGVRKG 96
           PR+  + K     GYGFN             ++ E   P Q++ +V P   A+  G+++G
Sbjct: 576 PRLCHLCKWADFDGYGFN-------------LHAEKDKPGQYIGSVDPNSPAETGGLKEG 716

Query: 97  DRILEVNGVNVEGATHKQVVDLIRA-GEKELILTV 130
           DRI+EVNG N+E   H  V+  I++ G+K  +L V
Sbjct: 717 DRIIEVNGENIETTNHTAVIQNIKSRGDKTSMLVV 821
>20073
          Length = 582

 Score = 51.6 bits (122), Expect = 8e-07,   Method: Compositional matrix adjust.
 Identities = 31/86 (36%), Positives = 50/86 (58%), Gaps = 1/86 (1%)
 Frame = +3

Query: 50  GYGFNVRGQVSEGGQLRSINGELYAPLQHVSAVLPGGAADRAG-VRKGDRILEVNGVNVE 108
           G GFNV G             E  +P+ ++S ++PGG ADR   +++GD++L VNGV+VE
Sbjct: 3   GLGFNVMG-----------GKEQSSPI-YISRIIPGGVADRLNCLKRGDQLLSVNGVSVE 146

Query: 109 GATHKQVVDLIRAGEKELILTVLSVP 134
           G  H++ V+L++  +  + L V   P
Sbjct: 147 GEYHEKAVELLKLAQGSVRLVVRYTP 224
>08480
          Length = 698

 Score = 39.3 bits (90), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 22/40 (55%), Positives = 29/40 (72%), Gaps = 2/40 (5%)
 Frame = -1

Query: 86  GAADRAG-VRKGDRILEVNGVNVEGATHKQVVD-LIRAGE 123
           G AD +G +R+GD+IL VN V+VE ATH+Q    L RAG+
Sbjct: 698 GPADLSGDLRRGDKILSVNDVDVERATHEQAAQALKRAGD 579
>38751
          Length = 329

 Score = 37.0 bits (84), Expect = 0.019,   Method: Composition-based stats.
 Identities = 26/83 (31%), Positives = 39/83 (46%)
 Frame = +3

Query: 70  GELYAPLQHVSAVLPGGAADRAGVRKGDRILEVNGVNVEGATHKQVVDLIRAGEKELILT 129
           G+ Y     V  +  G  A++ G+  GDRIL+VNG +    TH + V ++R     +I+T
Sbjct: 18  GKEYGTPIVVYVIEEGCQAEQQGLNIGDRILDVNGTDFTHLTHAEAVTIMRNAWN-VIMT 194

Query: 130 VLSVPPHEADNLDPSDDSLGQSF 152
           V   P         SD   GQ +
Sbjct: 195 VQPCP--------ESDSGQGQQY 239
>12345
          Length = 933

 Score = 34.3 bits (77), Expect = 0.14,   Method: Compositional matrix adjust.
 Identities = 19/88 (21%), Positives = 41/88 (46%), Gaps = 8/88 (9%)
 Frame = +3

Query: 193 KRYREFAILHQNLKREFANFTFPRLPGKWPFSLSEQQLDARRRGLEEYLEKVCSIRVIGE 252
           +RY +F  L++ +   F     P+LP K     + + ++ R++ L+ ++  +     I E
Sbjct: 300 RRYNDFVALYEMVMMRFPYRILPKLPPKKMLGANREFIEQRKKSLKRFINIIARHPQINE 479

Query: 253 SDIMQEFLSES--------DENYNGVSD 272
             +++ FL+ S         E + G+ D
Sbjct: 480 DKLLKFFLTYSGNDMQHKIKEQFRGIPD 563
>01502
          Length = 1949

 Score = 33.5 bits (75), Expect = 0.24,   Method: Compositional matrix adjust.
 Identities = 19/54 (35%), Positives = 32/54 (59%)
 Frame = +1

Query: 78  HVSAVLPGGAADRAGVRKGDRILEVNGVNVEGATHKQVVDLIRAGEKELILTVL 131
           +V+ +     A R G++  D+IL++NG +    THKQ V+ IR   K+ +L +L
Sbjct: 40  YVTFIYENSPAARCGLQLHDKILQLNGKDFTVVTHKQAVENIR---KKPVLKML 192
>02951
          Length = 1076

 Score = 33.1 bits (74), Expect = 0.32,   Method: Compositional matrix adjust.
 Identities = 19/54 (35%), Positives = 32/54 (59%)
 Frame = +2

Query: 78  HVSAVLPGGAADRAGVRKGDRILEVNGVNVEGATHKQVVDLIRAGEKELILTVL 131
           +V+ +     A R G++  D+IL++NG +    THKQ V+ IR   K+ +L +L
Sbjct: 26  YVTFIYENSPAARCGLQLHDKILQLNGKDFTVVTHKQAVENIR---KKPVLKML 178
>29705
          Length = 674

 Score = 30.8 bits (68), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 17/53 (32%), Positives = 33/53 (62%), Gaps = 1/53 (1%)
 Frame = -1

Query: 79  VSAVLPGGAADRAG-VRKGDRILEVNGVNVEGATHKQVVDLIRAGEKELILTV 130
           ++ V+ GG+A++ G +   DR+L VN  N+E  TH++ V  +++    + LT+
Sbjct: 353 ITKVIEGGSAEQDGRIAVMDRLLAVNEHNLEDVTHEEAVAALKSTGDVVRLTI 195
>05997
          Length = 807

 Score = 29.6 bits (65), Expect = 3.3,   Method: Compositional matrix adjust.
 Identities = 20/55 (36%), Positives = 29/55 (52%), Gaps = 3/55 (5%)
 Frame = +2

Query: 319 FEVINHSFVRKLAPNEFPHKLYVQNYTSAVPGTCLTIRKWLFTT---EEEVLLND 370
           F + NH   RKL  NE  +  Y+Q++T  V   C+  +K LF     EE V++ D
Sbjct: 641 FYLFNHIMTRKLL*NECNYFNYIQSHTKKVL-LCMNKKKILFIQSHYEESVIMCD 802
>18014
          Length = 469

 Score = 28.9 bits (63), Expect = 6.1,   Method: Composition-based stats.
 Identities = 16/59 (27%), Positives = 29/59 (49%), Gaps = 1/59 (1%)
 Frame = +2

Query: 392 KAEEKSYQLQKLHEQRKMVMYLNMLRTCEGYN-EIIFPHCACDSRRKGHVITAISITHF 449
           K+++ ++Q  +  + ++M   L   RTC   N    FP C CD  +  H I  + + +F
Sbjct: 71  KSKQIAFQ*TRNSKSQRMHKLLKKSRTCPKNNLSF*FPFCVCDKFKTLHNIHYVLVGYF 247
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|163310776|ref|NP_033810.2| adaptor-related protein
complex 3, beta 1 subunit [Mus musculus]
         (1105 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

31995                                                                 388   e-127
06708                                                                 177   2e-44
18633                                                                  50   4e-06
>31995
          Length = 1263

 Score =  388 bits (997), Expect(2) = e-127,   Method: Compositional matrix adjust.
 Identities = 195/263 (74%), Positives = 227/263 (86%)
 Frame = -2

Query: 340  LVRLLRSNREVQYIVLQNIATMSIERKGMFEPYLKSFYVRSTDPTMIKTLKLEILTNLAN 399
            L+RLLRS++E+QY+VL ++ATM+ +RKGMFEPYLKSFYVRS+DP  IK LKLEILTNLA 
Sbjct: 1262 LIRLLRSHQEIQYVVLSDVATMTTKRKGMFEPYLKSFYVRSSDPLHIKLLKLEILTNLAT 1083

Query: 400  EANISTLLREFQTYVRSQDKQFAAATIQTIGRCATSISEVTDTCLNGLVCLLSNRDEIVV 459
            E NIST+LREFQTYV S DK+FAAATIQ IGRCA+SI EVTDTCLNGLV L+SNRBE VV
Sbjct: 1082 ETNISTILREFQTYVTSSDKEFAAATIQAIGRCASSICEVTDTCLNGLVHLMSNRBEAVV 903

Query: 460  AESVVVIKKLLQMQPAQHGEIIRHMAKLLDSITVPVARASILWLIGENCERVPKIAPDVL 519
            AESVVVIKKLLQM+P +H  II HMA+++D ITVP+ARASILWLIGE  ERVPKIAPDVL
Sbjct: 902  AESVVVIKKLLQMRPNEHKGIICHMARMVDKITVPMARASILWLIGEYSERVPKIAPDVL 723

Query: 520  RKMAKSFTSEDDLVKLQILNLAAKLYLTNSKQTKLLTQYILNLGKYDQNYDIRDRTRFIR 579
            RK+AKSFTSE+D+VKLQ+LNLA KL +TN KQTKLL QY+LNL KYDQNYDIRDR+RF+R
Sbjct: 722  RKLAKSFTSEEDIVKLQVLNLATKLCITNPKQTKLLCQYVLNLAKYDQNYDIRDRSRFLR 543

Query: 580  QLIVPNEKSGALSKYAKKIFLAP 602
            Q+++P E     SKYAK+    P
Sbjct: 542  QMVLPGENGCVFSKYAKRCSWPP 474

 Score = 86.7 bits (213), Expect(2) = e-127,   Method: Compositional matrix adjust.
 Identities = 43/73 (58%), Positives = 51/73 (69%)
 Frame = -3

Query: 605 APLLESPFKDRDRFQLGTLSHTLNIKASGYLELSNWPEVAPDPSVRNVEVIESAKEWTPL 664
           AP+L S FKDRD FQLGTLSH LN++ +GY EL  WPE APDPSVRNVE+     E    
Sbjct: 469 APVLASKFKDRDFFQLGTLSHVLNMRTTGYQELPEWPEAAPDPSVRNVELPPVWTEKPSK 290

Query: 665 GKTKKEKPMKKFY 677
             TKK++ +K FY
Sbjct: 289 VSTKKKQDLKSFY 251
>06708
          Length = 980

 Score =  177 bits (449), Expect = 2e-44,   Method: Compositional matrix adjust.
 Identities = 96/237 (40%), Positives = 147/237 (62%)
 Frame = +1

Query: 866  SSVINVSTPVFVPTKTHELLHRMHGKGLAAHYCFPRQPCIFSDKMVSVQITLTNTSDRKI 925
            ++V N+   + V +K+HELL+R+ G GL+  Y F R   +FS KMVS++ TL N  D  +
Sbjct: 151  ATVTNIVQGITVSSKSHELLNRISGSGLSISYKFTRTISVFSPKMVSIEWTLINNGDTPL 330

Query: 926  ENIHIGGKGLPVGMQMHAFHPIDSLEPKGSVTVSVGIDFCDSTQTASFQLCTKDDCFNVT 985
             +I +G   +  GM++  F  I SL    S +V +GI+F D+TQ A+  +C  +  F V+
Sbjct: 331  TSIKLGDTKVQPGMEVQPFPEIASLGVGASTSVLMGINFNDTTQPAAMDVCVGEHKFKVS 510

Query: 986  LQPPVGELLSPVAMSEKDFKKEQGTLTGMNETSATLIAAPQNFTPSMILQKVVNVANLGA 1045
            +  PVGELL P  MSE DF  +QG L GMNE SA++    +  +   I   V+   NL  
Sbjct: 511  ITAPVGELLQPHTMSEGDFTLQQGKLGGMNENSASVAIDEETGSAKAICTSVLTAGNLLQ 690

Query: 1046 VPSSQDNVHRFAARTVHSGSLMLVTVELKEGSTAQLIINTEKTVIGSVLLRELKPVL 1102
            VPSS +N+ RFAA+T+ SG+L+LVTV+  E   A++ +N+EK VI ++LL++++  +
Sbjct: 691  VPSSDENIFRFAAKTLASGTLVLVTVKTSE-KKAKVTVNSEKMVICAMLLKDVQKAM 858
>18633
          Length = 404

 Score = 50.4 bits (119), Expect = 4e-06,   Method: Composition-based stats.
 Identities = 22/48 (45%), Positives = 36/48 (75%)
 Frame = +2

Query: 77  SELFPAVVKNVASKNIEIKKLVYVYLVRYAEEQQDLALLSISTFQRAL 124
           S LF  VV  + ++N+E+KKLVY+YL+ YA+ Q D A++S++TF + +
Sbjct: 161 SALFTDVVNCMQTENLELKKLVYLYLMNYAKSQSDTAIISVNTFVKVI 304
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|28395018|ref|NP_034723.1| junction plakoglobin [Mus
musculus]
         (745 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

14657                                                                 450   e-126
15086                                                                 271   7e-73
38361                                                                  98   8e-23
12505                                                                  91   1e-18
17600                                                                  82   9e-16
12579                                                                  42   9e-04
36452                                                                  39   0.005
22653                                                                  32   0.64 
36960                                                                  32   1.1  
02294                                                                  30   4.5  
>14657
          Length = 918

 Score =  450 bits (1157), Expect = e-126,   Method: Compositional matrix adjust.
 Identities = 221/296 (74%), Positives = 258/296 (87%), Gaps = 2/296 (0%)
 Frame = -3

Query: 103 ATQVE-GQTTNLQRLAEPSQLLKSAIVHLINYQDDAELATRALPELTKLLNDEDPVVVTK 161
           +TQV   + T +QRL+EPSQ+LK A+V+LINYQDDA+LATRA+PEL KLL DED VVV +
Sbjct: 889 STQVHPDEPTAVQRLSEPSQMLKHAVVNLINYQDDADLATRAIPELIKLLXDEDXVVVYQ 710

Query: 162 AAMIVNQLSKKEASRRALMGSPQLVAAVVRTMQNTSDLDTARCTTSILHNLSHHREGLLA 221
           AAM+V+QLSKKEASR A+M SPQ++AA++R M NT D++T RC    LHNLSHHR+GLLA
Sbjct: 709 AAMMVHQLSKKEASRHAIMNSPQMIAALIRAMANTEDIETTRCAAGTLHNLSHHRQGLLA 530

Query: 222 IFKSGGIPALVRMLSSPVESVLFYAITTLHNLLLYQEGAKMAVRLADGLQKMVPLLNK-N 280
           IFKSGGIPALV++LSSP+ESVLFYAITTLHNLLL+QEG+KMAVRLA GLQKMV LL + N
Sbjct: 529 IFKSGGIPALVKLLSSPMESVLFYAITTLHNLLLHQEGSKMAVRLAGGLQKMVALLQRNN 350

Query: 281 NPKFLAITTDCLQLLAYGNQESKLIILANGGPQGLVQIMRNYSYEKLLWTTSRVLKVLSV 340
           N KFLAITTDCLQ+LAYGNQESKLIILA+GGP  LV+IM++Y+YEKLLWTTSRVLKVLSV
Sbjct: 349 NVKFLAITTDCLQILAYGNQESKLIILASGGPGELVRIMKSYTYEKLLWTTSRVLKVLSV 170

Query: 341 CPSNKPAIVEAGGMQALGKHLTSNSPRLVQNCLWTLRNLSDVATKQEGLESVLKIL 396
           CPSNKPAIVEAGGMQAL  HL   S RLVQNCLW+LRNLSD ATK + +E +L +L
Sbjct: 169 CPSNKPAIVEAGGMQALAMHLGHQSQRLVQNCLWSLRNLSDAATKMDNMEGLLHML 2

 Score = 28.5 bits (62), Expect = 9.4,   Method: Compositional matrix adjust.
 Identities = 35/131 (26%), Positives = 61/131 (46%)
 Frame = -3

Query: 380 SDVATKQEGLESVLKILVNQLSVDDVNVLTCATGTLSNLTCNNSKNKTLVTQNSGVEALI 439
           +D+AT+   +  ++K+L +    +D  V+  A   +  L+   +    ++     + ALI
Sbjct: 784 ADLATR--AIPELIKLLXD----EDXVVVYQAAMMVHQLSKKEASRHAIMNSPQMIAALI 623

Query: 440 HAILRAGDKDDITEPAVCALRHLTSRHPEAEMAQNSVRLNYGIPAIVKLLNQPNQWPLVK 499
            A+  A  +D  T        H  S H +  +A   +  + GIPA+VKLL+ P +  L  
Sbjct: 622 RAM--ANTEDIETTRCAAGTLHNLSHHRQGLLA---IFKSGGIPALVKLLSSPMESVLFY 458

Query: 500 ATIGLIRNLAL 510
           A I  + NL L
Sbjct: 457 A-ITTLHNLLL 428
>15086
          Length = 548

 Score =  271 bits (693), Expect = 7e-73,   Method: Compositional matrix adjust.
 Identities = 130/171 (76%), Positives = 152/171 (88%), Gaps = 1/171 (0%)
 Frame = +1

Query: 143 ALPELTKLLNDEDPVVVTKAAMIVNQLSKKEASRRALMGSPQLVAAVVRTMQNTSDLDTA 202
           A+PEL KLL+DED VVV +AAM+V+QLSKKEASR A+M SPQ++AA++R +  T D++T 
Sbjct: 1   AIPELIKLLSDEDQVVVCQAAMMVHQLSKKEASRHAIMNSPQMIAALIRALATTDDMETT 180

Query: 203 RCTTSILHNLSHHREGLLAIFKSGGIPALVRMLSSPVESVLFYAITTLHNLLLYQEGAKM 262
           RC    LHNLSHHR+GLLAIFKSGGIPALV++LSSPVESVLFYAITTLHNLLL+QEG+KM
Sbjct: 181 RCAAGTLHNLSHHRQGLLAIFKSGGIPALVKLLSSPVESVLFYAITTLHNLLLHQEGSKM 360

Query: 263 AVRLADGLQKMVPLLNK-NNPKFLAITTDCLQLLAYGNQESKLIILANGGP 312
           AVR+A GLQKMV LL + NN KFLAITTDCLQ+LAYGNQESKLIILA+GGP
Sbjct: 361 AVRMAGGLQKMVALLQRNNNVKFLAITTDCLQILAYGNQESKLIILASGGP 513

 Score = 29.6 bits (65), Expect = 4.5,   Method: Compositional matrix adjust.
 Identities = 27/75 (36%), Positives = 38/75 (50%), Gaps = 2/75 (2%)
 Frame = +1

Query: 438 LIHAILRAGDKDDITEPAVCA--LRHLTSRHPEAEMAQNSVRLNYGIPAIVKLLNQPNQW 495
           +I A++RA    D  E   CA    H  S H +  +A   +  + GIPA+VKLL+ P + 
Sbjct: 127 MIAALIRALATTDDMETTRCAAGTLHNLSHHRQGLLA---IFKSGGIPALVKLLSSPVES 297

Query: 496 PLVKATIGLIRNLAL 510
            L  A I  + NL L
Sbjct: 298 VLFYA-ITTLHNLLL 339
>38361
          Length = 227

 Score = 98.2 bits (243), Expect(2) = 8e-23,   Method: Compositional matrix adjust.
 Identities = 42/56 (75%), Positives = 53/56 (94%)
 Frame = -1

Query: 455 AVCALRHLTSRHPEAEMAQNSVRLNYGIPAIVKLLNQPNQWPLVKATIGLIRNLAL 510
           +VCALRHLTSRHPEAEMAQN+VRL+YG+P +VKLL+ P++WPL+KA +GL+RNLAL
Sbjct: 170 SVCALRHLTSRHPEAEMAQNAVRLHYGLPVLVKLLHPPSRWPLIKAVVGLVRNLAL 3

 Score = 27.7 bits (60), Expect(2) = 8e-23,   Method: Compositional matrix adjust.
 Identities = 8/17 (47%), Positives = 14/17 (82%)
 Frame = -3

Query: 438 LIHAILRAGDKDDITEP 454
            +  +++AGD++DITEP
Sbjct: 225 FVRTVMQAGDREDITEP 175
>12505
          Length = 836

 Score = 91.3 bits (225), Expect = 1e-18,   Method: Compositional matrix adjust.
 Identities = 45/73 (61%), Positives = 49/73 (67%)
 Frame = -3

Query: 589 FVQLLYSSVENIQRVAAGVLCELXXXXXXXXXXXXXXXXXPLMELLHSRNEGTATYAAAV 648
           + QLLYS +ENIQRVAAGVLCEL                 PL ELLHSRNEG  TYAAAV
Sbjct: 711 YHQLLYSPIENIQRVAAGVLCELAADKEGAEMIEQEGATAPLTELLHSRNEGVXTYAAAV 532

Query: 649 LFRISEDKNPDYR 661
           LFR+SEDK  DY+
Sbjct: 531 LFRMSEDKPQDYK 493

 Score = 77.8 bits (190), Expect = 2e-14,   Method: Composition-based stats.
 Identities = 35/41 (85%), Positives = 41/41 (100%)
 Frame = -1

Query: 209 LHNLSHHREGLLAIFKSGGIPALVRMLSSPVESVLFYAITT 249
           LHNLSHHR+GLLAIF+SGGIPALV++LSSP+ESVLFYAIT+
Sbjct: 824 LHNLSHHRQGLLAIFRSGGIPALVKLLSSPMESVLFYAITS 702
>17600
          Length = 752

 Score = 81.6 bits (200), Expect = 9e-16,   Method: Compositional matrix adjust.
 Identities = 44/82 (53%), Positives = 54/82 (65%), Gaps = 4/82 (4%)
 Frame = +1

Query: 629 PLMELLHSRNEGTATYAAAVLFRISEDKNPDYRKRVSVELTNSLFKHDPAAWEAAQSMIP 688
           PL +LLHSRNEG ATYAAAVLFR+SEDK  DY+KR+S+ELT+SL++ D   W        
Sbjct: 292 PLTDLLHSRNEGVATYAAAVLFRMSEDKPQDYKKRLSMELTSSLYRGDNMNWSEP----- 456

Query: 689 INEPYADDM----DATYRPMYS 706
              P  +DM    D +  PMYS
Sbjct: 457 ---PGFEDMGLLTDTSRDPMYS 513
>12579
          Length = 1870

 Score = 42.0 bits (97), Expect = 9e-04,   Method: Compositional matrix adjust.
 Identities = 32/97 (32%), Positives = 46/97 (47%), Gaps = 9/97 (9%)
 Frame = +2

Query: 4   MNLIEQPI-----KVTEWQQT-YTYDSGIHSGVNTCVPSVSSKG---IMDEDDACGRXXX 54
           M L++ P+     +   WQQ  Y  DSGIHSG  T  PS+SSKG    ++E D       
Sbjct: 83  MELLDMPVDSKHEQTMMWQQNQYLADSGIHSGATTQAPSISSKGHGEELEEGDMDPTKMF 262

Query: 55  XXXXXXXXXGVPQNQGDLEYQMSTTARAKRVREAMCP 91
                      P+   ++  Q++ T R +RVR A+ P
Sbjct: 263 DWGLPDPFTPQPEQVEEMNQQLNQT-RPQRVRAAIFP 370
>36452
          Length = 607

 Score = 39.3 bits (90), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 56/222 (25%), Positives = 82/222 (36%), Gaps = 43/222 (19%)
 Frame = +1

Query: 404 DVNVLTCATGTLSNLTCNNSKNKTLVTQNSGVEALIHAILRAGDKDDITEPAVCALRHLT 463
           DV V  C  G L+  +C+ SK      Q +G   L+  +L++   +D+  P V  L+   
Sbjct: 7   DVEVARC--GALALWSCSKSKKNKEAMQRAGAIPLLAKLLKS-PHEDMLIPVVGTLQECA 177

Query: 464 SR-----------------------------HPEAEM--------------AQNSVRLNY 480
           S                              +PE +M               ++ VR   
Sbjct: 178 SEPSYRLAIRTEGMIEDLVKNLKSSVPDKPANPELQMHCASAIFKCAEEKETRDLVRQYG 357

Query: 481 GIPAIVKLLNQPNQWPLVKATIGLIRNLALCPANHAPLQEAAVIPRLVQLLVKAHQDAQR 540
           G+  +V LLN+ +   L+ A  G I   A+ P N A  QE   I  LV LL         
Sbjct: 358 GLDPLVGLLNKMDNKELLAAATGAIWKCAISPENVARFQELKCIELLVALL--------- 510

Query: 541 HVAAGTQQPYTDGVRMEEIVEGCTGALHILARDPMNRMEIFR 582
                T QP       EE++    GAL  LA+   NR +I +
Sbjct: 511 -----TNQP-------EEVLVNVVGALGELAKAQPNRAQIRK 600
>22653
          Length = 1347

 Score = 32.3 bits (72), Expect = 0.64,   Method: Compositional matrix adjust.
 Identities = 37/172 (21%), Positives = 64/172 (37%)
 Frame = +3

Query: 481 GIPAIVKLLNQPNQWPLVKATIGLIRNLALCPANHAPLQEAAVIPRLVQLLVKAHQDAQR 540
           G+  IV LL   ++  ++ A    I N+A    N A + +  V+P L +L +      ++
Sbjct: 120 GLELIVSLLKSEDK-EVLAAVCAAIANIAKDEENLAVITDHGVVPMLAKLTLTTDDKLRQ 296

Query: 541 HVAAGTQQPYTDGVRMEEIVEGCTGALHILARDPMNRMEIFRLNTIPLFVQLLYSSVENI 600
           H+A             E I   C            NR    + N +   V+ L S  EN+
Sbjct: 297 HLA-------------EAIARCCNWG--------NNRTAFGKENAVAPLVRYLKSKDENV 413

Query: 601 QRVAAGVLCELXXXXXXXXXXXXXXXXXPLMELLHSRNEGTATYAAAVLFRI 652
            R  A  L +L                 PL++++ S ++     +A  +  I
Sbjct: 414 HRSTARALFQLSKNPENCITMHEAGVVQPLLKMVGSADDDLQESSAGCISNI 569
>36960
          Length = 551

 Score = 32.0 bits (71), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 18/43 (41%), Positives = 24/43 (55%)
 Frame = +3

Query: 222 IFKSGGIPALVRMLSSPVESVLFYAITTLHNLLLYQEGAKMAV 264
           I  +GGIP ++  LSS  E  +  AITTL  L+  Q  A + V
Sbjct: 321 IVTNGGIPLVINCLSSCSEETVMSAITTLMYLITPQSQAAITV 449
>02294
          Length = 517

 Score = 29.6 bits (65), Expect = 4.5,   Method: Composition-based stats.
 Identities = 17/49 (34%), Positives = 22/49 (44%)
 Frame = +3

Query: 329 WTTSRVLKVLSVCPSNKPAIVEAGGMQALGKHLTSNSPRLVQNCLWTLR 377
           W+ S   K++ +C    P I  AGG     KH     P+  QNC   LR
Sbjct: 255 WSXSGRSKLIGLCIVRAPPIGSAGGDNCQYKHSF*IVPKYKQNCQILLR 401
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|34147045|ref|NP_032851.2|
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 [Mus musculus]
         (518 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

04908                                                                 448   e-126
26366                                                                 259   2e-69
18743                                                                 142   3e-34
10738                                                                  36   0.037
33076                                                                  29   5.4  
08153                                                                  28   9.0  
>04908
          Length = 1856

 Score =  448 bits (1153), Expect = e-126,   Method: Compositional matrix adjust.
 Identities = 215/420 (51%), Positives = 298/420 (70%), Gaps = 1/420 (0%)
 Frame = +3

Query: 35  YMTNSPTLIVMIGLPARGKTYVSKKLTRYLNWIGVPTKVFNLGVYRREAVKSYQSYDFFR 94
           ++ + PT+I M+GLPARGKTY  +KL RYLNW+G+ TKVFN+G YRR       S++FFR
Sbjct: 261 FVIDRPTVIAMVGLPARGKTYTGRKLMRYLNWVGIKTKVFNVGNYRRCVATGVSSHNFFR 440

Query: 95  HDNEEAMKIRKQCALVALEDVKAYFTEESGQIAVFDATNTTRERRDMILN-FAKQNAFKV 153
            +N EA ++R+Q A++A+ D   Y  E  G++A+FDATNTTRERR ++ + F K++ + +
Sbjct: 441 PNNAEAKEMRQQSAMLAIADTCKYM-ENGGEVAIFDATNTTRERRQLLAHHFTKEHPYDL 617

Query: 154 FFVESVCDDPDVIAANILEVKVSSPDYPERNRENVMEDFLKRIECYKVTYQPLDPDNYDK 213
           FFVESVCDD D I +NILEVKV  PDY  +N++  M DFL+RIE Y+  Y  LD    D+
Sbjct: 618 FFVESVCDDLDQIESNILEVKVDGPDYNGQNKDEAMVDFLQRIEHYREVYNRLDSPG-DE 794

Query: 214 DLSFIKVINVGQRFLVNRVQDYIQSKIVYYLMNIHVHPRTIYLCRHGESEFNLLGKIGGD 273
              FI++I+ G+R +VN     +QS++++YLMN+ V  + IY+ RHGES  N  GKIGGD
Sbjct: 795 MTPFIQIIDQGRRLVVNNPVGVLQSRVLFYLMNVKVMRQPIYMTRHGESVMNRQGKIGGD 974

Query: 274 SGLSVRGKQFAHALKKFLEEQEIQDLKVWTSQLKRTIQTAESLGVTYEQWKILNEIDAGV 333
           S LS +G ++A  L +++  + I  LKVWTS +KRT QTA+ +      WKILNEI+AGV
Sbjct: 975 SDLSDQGLKYAEVLAQYMAGEHITGLKVWTSHMKRTSQTAQFIDAPQRPWKILNEINAGV 1154

Query: 334 CEEMTYSEIEQRYPEEFALRDQEKYLYRYPGGESYQDLVQRLEPVIMELERQGNILVISH 393
           CE ++Y EI+++YP EFA RD++K+ YRYP GESY DLV RLE +I+ LE + N+L++ H
Sbjct: 1155CEGLSYEEIQEKYPSEFAQRDKDKFRYRYPDGESYLDLVARLETIILALEHEENVLIVGH 1334

Query: 394 QAVMRCLLAYFLDKGADELPYLRCPLHIIFKLTPVAYGCKVETITLNVDAVDTHRDKPTH 453
           QAV+RCLLA+F     D+L +++  LH + KLTP A+G KVE I L+V AV THR KP +
Sbjct: 1335QAVLRCLLAFFEGVDHDDLAHMQIDLHTVIKLTPTAFGPKVERIRLDVPAVSTHRAKPAN 1514
>26366
          Length = 546

 Score =  259 bits (661), Expect = 2e-69,   Method: Compositional matrix adjust.
 Identities = 122/178 (68%), Positives = 142/178 (79%)
 Frame = +1

Query: 264 FNLLGKIGGDSGLSVRGKQFAHALKKFLEEQEIQDLKVWTSQLKRTIQTAESLGVTYEQW 323
            NL G+IGGDS LS RG  +A AL +F+EE+ I  LKVWTS+LKRTIQT+  +    E W
Sbjct: 13  MNLQGRIGGDSDLSDRGWSYAEALGRFVEEENIPQLKVWTSELKRTIQTSRHINAPKEHW 192

Query: 324 KILNEIDAGVCEEMTYSEIEQRYPEEFALRDQEKYLYRYPGGESYQDLVQRLEPVIMELE 383
           K LNEIDAGVCE MTY EI+ +YPEEFALRDQ+K+ YRYP GESYQDLV RLEPVI+ELE
Sbjct: 193 KALNEIDAGVCEGMTYEEIQNKYPEEFALRDQDKFHYRYPSGESYQDLVARLEPVILELE 372

Query: 384 RQGNILVISHQAVMRCLLAYFLDKGADELPYLRCPLHIIFKLTPVAYGCKVETITLNV 441
           RQ N++VI HQAV RCLLAYF DK A +LPYL+ PLH + KLTPVAYGC+VE + LNV
Sbjct: 373 RQENVMVICHQAVCRCLLAYFQDKSAHDLPYLKVPLHTVIKLTPVAYGCRVEFLALNV 546
>18743
          Length = 465

 Score =  142 bits (358), Expect = 3e-34,   Method: Compositional matrix adjust.
 Identities = 61/109 (55%), Positives = 87/109 (79%)
 Frame = +2

Query: 35  YMTNSPTLIVMIGLPARGKTYVSKKLTRYLNWIGVPTKVFNLGVYRREAVKSYQSYDFFR 94
           ++  +PT+I M+GLPARGKTY+SKKLTRYLNWIG+ T+ FN+G YRR A  SY++++FFR
Sbjct: 107 HIVRAPTVIAMVGLPARGKTYISKKLTRYLNWIGISTRAFNVGEYRRAATNSYKNHNFFR 286

Query: 95  HDNEEAMKIRKQCALVALEDVKAYFTEESGQIAVFDATNTTRERRDMIL 143
            DN+EA ++R +CAL+A++D    F E  G++AV DATNTT+ RR +++
Sbjct: 287 SDNKEAQELRTKCALMAVDDA-CKFLENGGEVAVIDATNTTQARRRLLV 430
>10738
          Length = 1860

 Score = 36.2 bits (82), Expect = 0.037,   Method: Compositional matrix adjust.
 Identities = 50/200 (25%), Positives = 81/200 (40%), Gaps = 40/200 (20%)
 Frame = -2

Query: 252  RTIYLCRHGESEFNLLGKIGG--DSGLSVRGKQFAHALKKFLEEQEIQDLKVWTSQLKRT 309
             T+ L RHGESE+N      G  D+ LS  G   A    + ++++       +TS LKR 
Sbjct: 1730 HTLILVRHGESEWNKQNLFCGWHDADLSEAGXNEAKYAAQLIKDKGYLYDIAFTSVLKRA 1551

Query: 310  IQTAESLGVTYEQ--------WKILNEIDAGVCEEMTYSEIEQRYPEE------------ 349
            I+T   +    ++        W+ LNE   G  + +  +E   ++ E+            
Sbjct: 1550 IKTLYLIQDGTDRHWVPVLRSWR-LNERHYGGLQGLNKAETAAKHGEDQVKIWRRSYDVP 1374

Query: 350  ---FALRDQE------KYLYR----YPGGESYQDLVQRLEP-----VIMELERQGNILVI 391
                  +D E      KY        P  E  +D V R+ P     ++ EL+    +L+ 
Sbjct: 1373 PPPLTPKDAEWSGNDPKYTKLDPNVIPACECLKDTVARVLPYWSDAIVPELKEGKTVLIA 1194

Query: 392  SHQAVMRCLLAYFLDKGADE 411
            +H   +R L+ Y LD   DE
Sbjct: 1193 AHGNSLRALVKY-LDNMTDE 1137
>33076
          Length = 1174

 Score = 28.9 bits (63), Expect = 5.4,   Method: Compositional matrix adjust.
 Identities = 10/38 (26%), Positives = 22/38 (57%)
 Frame = -1

Query: 234 DYIQSKIVYYLMNIHVHPRTIYLCRHGESEFNLLGKIG 271
           D + + I++ L N+H H   ++ CRH  +   ++ ++G
Sbjct: 907 DTVSTHILHTLTNVHTHTHDLHTCRHTHTVHFVVRQLG 794
>08153
          Length = 1703

 Score = 28.1 bits (61), Expect = 9.0,   Method: Compositional matrix adjust.
 Identities = 37/127 (29%), Positives = 56/127 (44%)
 Frame = +1

Query: 43  IVMIGLPARGKTYVSKKLTRYLNWIGVPTKVFNLGVYRREAVKSYQSYDFFRHDNEEAMK 102
           I+M+GL A GKT +  KL        +PT  FN+     E V+ Y++  F   D     K
Sbjct: 91  ILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNV-----ETVE-YKNISFTVWDVGGQDK 252

Query: 103 IRKQCALVALEDVKAYFTEESGQIAVFDATNTTRERRDMILNFAKQNAFKVFFVESVCDD 162
           IR           + YF    G I V D+ +  RER    +N AK+   ++   + + D 
Sbjct: 253 IRPLW--------RHYFQNTQGLIFVVDSND--RER----INEAKEELARMLNEDDLRDA 390

Query: 163 PDVIAAN 169
             ++ AN
Sbjct: 391 IILVFAN 411
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|12963615|ref|NP_075768.1| tubulin, beta 3 [Mus
musculus]
         (450 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

13181                                                                 446   e-125
16482                                                                 441   e-124
04882                                                                 424   e-119
00276                                                                 274   6e-74
28905                                                                 250   2e-67
31457                                                                 239   1e-63
25015                                                                 221   5e-58
39157                                                                 211   9e-58
12457                                                                 207   9e-54
05902                                                                 157   1e-38
06360                                                                 131   6e-31
03702                                                                 122   4e-28
17215                                                                  83   2e-16
29025                                                                  33   0.17 
24946                                                                  28   9.8  
>13181
          Length = 1092

 Score =  446 bits (1146), Expect = e-125,   Method: Compositional matrix adjust.
 Identities = 208/219 (94%), Positives = 214/219 (97%)
 Frame = -3

Query: 208  YDICFRTLKLATPTYGDLNHLVSATMSGVTTSLRFPGQLNADLRKLAVNMVPFPRLHFFM 267
            YDICFRTLKL TPTYGDLNHLVSATMSGVTT LRFPGQLNADLRKLAVNMVPFPRLHFFM
Sbjct: 1090 YDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFM 911

Query: 268  PGFAPLTARGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVATVFRGRMSMKEVD 327
            PGFAPLT+RGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVA +FRGRMSMKEVD
Sbjct: 910  PGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAMFRGRMSMKEVD 731

Query: 328  EQMLAIQSKNSSYFVEWIPNNVKVAVCDIPPRGLKMSSTFIGNSTAIQELFKRISEQFTA 387
            EQML +Q+KNSSYFVEWIPNNVK AVCDIPPRGLKMS+TF+GNSTAIQELFKRISEQFTA
Sbjct: 730  EQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFVGNSTAIQELFKRISEQFTA 551

Query: 388  MFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQ 426
            MFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQ
Sbjct: 550  MFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQ 434
>16482
          Length = 837

 Score =  441 bits (1133), Expect = e-124,   Method: Compositional matrix adjust.
 Identities = 208/246 (84%), Positives = 218/246 (88%)
 Frame = +1

Query: 1   MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPSGNYVGDSDLQLERISVYYNEASSHKYV 60
           MREIVH+QAGQCGNQIGAKFWEVISDEHGIDP+G Y GDSDLQLERI+VYYNEA+  KYV
Sbjct: 100 MREIVHMQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEATGGKYV 279

Query: 61  PRAILVDLEPGTMDSVRSGAFGHLFRPDNFIFGQSGAGNNWAKGHYTEGAELVDSVLDVV 120
           PRA+LVDLEPGTMDSVRSG FG +FRPDNF+FGQSGAGNNWAKGHYTEGAELVDSVLDVV
Sbjct: 280 PRAVLVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVV 459

Query: 121 RKECENCDCLQGFQXXXXXXXXXXXXXXXXXXXKVREEYPDRIMNTFSVVPSPKVSDTVV 180
           RKE E+CDCLQGFQ                   K+REEYPDRIMNTFSVVPSPKVSDTVV
Sbjct: 460 RKEAESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVVPSPKVSDTVV 639

Query: 181 EPYNATLSIHQLVENTDETYCIDNEALYDICFRTLKLATPTYGDLNHLVSATMSGVTTSL 240
           EPYNATLS+HQLVENTDETYCIDNEALYDICFRTLKL TPTYGDLNHLVSATMSGVTT L
Sbjct: 640 EPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCL 819

Query: 241 RFPGQL 246
           RFPGQL
Sbjct: 820 RFPGQL 837
>04882
          Length = 1136

 Score =  424 bits (1090), Expect = e-119,   Method: Compositional matrix adjust.
 Identities = 198/208 (95%), Positives = 204/208 (98%)
 Frame = +2

Query: 219 TPTYGDLNHLVSATMSGVTTSLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTARGS 278
           TPTYGDLNHLVSATMSGVTT LRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLT+RGS
Sbjct: 320 TPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGS 499

Query: 279 QQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVATVFRGRMSMKEVDEQMLAIQSKNS 338
           QQYRALTVPELTQQMFD+KNMMAACDPRHGRYLTVA +FRGRMSMKEVDEQML +Q+KNS
Sbjct: 500 QQYRALTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNS 679

Query: 339 SYFVEWIPNNVKVAVCDIPPRGLKMSSTFIGNSTAIQELFKRISEQFTAMFRRKAFLHWY 398
           SYFVEWIPNNVK AVCDIPPRGLKMS+TFIGNSTAIQELFKRISEQFTAMFRRKAFLHWY
Sbjct: 680 SYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWY 859

Query: 399 TGEGMDEMEFTEAESNMNDLVSEYQQYQ 426
           TGEGMDEMEFTEAESNMNDLVSEYQQYQ
Sbjct: 860 TGEGMDEMEFTEAESNMNDLVSEYQQYQ 943
>00276
          Length = 1330

 Score =  274 bits (700), Expect = 6e-74,   Method: Compositional matrix adjust.
 Identities = 131/355 (36%), Positives = 204/355 (57%), Gaps = 8/355 (2%)
 Frame = -3

Query: 78   SGAFGHLFRPDNFIFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKECENCDCLQGFQXXX 137
            +G +  L  P+  + G+  A NN+A+GHYT G ELVD VLD +RK  + C  LQGF    
Sbjct: 1328 TGTYRQL-SPEQLVTGKEDAANNYARGHYTIGKELVDLVLDRIRKLADQCTGLQGFLIFH 1152

Query: 138  XXXXXXXXXXXXXXXXKVREEYPDRIMNTFSVVPSPKVSDTVVEPYNATLSIHQLVENTD 197
                            ++  +Y  +    F + P+P+VS  VVEPYN+ L+ H  +E++D
Sbjct: 1151 SFGGGTGSGFTSLXMERLSVDYGKKSKLEFXIYPAPQVSTAVVEPYNSILTTHTTLEHSD 972

Query: 198  ETYCIDNEALYDICFRTLKLATPTYGDLNHLVSATMSGVTTSLRFPGQLNADLRKLAVNM 257
              + +DNEA+YDIC R L +  PTY +LN L+   +S +T SLRF G LN DL +   N+
Sbjct: 971  CAFMVDNEAIYDICRRNLDIERPTYTNLNRLIXQIVSSITASLRFDGALNVDLTEFQTNL 792

Query: 258  VPFPRLHFFMPGFAPLTARGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVATVF 317
            VP+PR+HF +  +AP+ +     +  L V E+T   F+  N +  CDPRHG+Y+    ++
Sbjct: 791  VPYPRIHFPLATYAPVISAEKAYHEQLXVAEITNACFEPANQLVKCDPRHGKYMACCMLY 612

Query: 318  RGRMSMKEVDEQMLAIQSKNSSYFVEWIPNNVKVAVCDIPPR--------GLKMSSTFIG 369
            RG +  K+V+  +  I++K +  FV+W P   KV +   PP          ++ +   + 
Sbjct: 611  RGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLS 432

Query: 370  NSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQ 424
            N+TAI E + R+  +F  M+ ++AF+HWY GEGM+E EF+EA  ++  L  +Y++
Sbjct: 431  NTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEE 267
>28905
          Length = 425

 Score =  250 bits (639), Expect(2) = 2e-67,   Method: Compositional matrix adjust.
 Identities = 118/129 (91%), Positives = 123/129 (95%), Gaps = 1/129 (0%)
 Frame = -1

Query: 253 LAVNMVPFPRLHFFMPGFAPLTARGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLT 312
           +AVNMVPFPRLHFFMPGFAPLT+RGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLT
Sbjct: 389 VAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLT 210

Query: 313 VATVFRGRMSMKEVDEQMLAIQSKNSSYFVEWIPNNVKVAVCDIPPRGLKMSSTFIGNST 372
           VA +FRGRMSMKEVDEQML +Q+KNSSYFVEWIPNNVK AVCDIPPRGLKMS TFIGNST
Sbjct: 209 VAAMFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSGTFIGNST 30

Query: 373 AIQ-ELFKR 380
           AIQ  LFKR
Sbjct: 29  AIQGRLFKR 3

 Score = 23.9 bits (50), Expect(2) = 2e-67,   Method: Composition-based stats.
 Identities = 9/9 (100%), Positives = 9/9 (100%)
 Frame = -2

Query: 242 FPGQLNADL 250
           FPGQLNADL
Sbjct: 424 FPGQLNADL 398
>31457
          Length = 1530

 Score =  239 bits (611), Expect = 1e-63,   Method: Compositional matrix adjust.
 Identities = 111/118 (94%), Positives = 115/118 (97%)
 Frame = +3

Query: 309 RYLTVATVFRGRMSMKEVDEQMLAIQSKNSSYFVEWIPNNVKVAVCDIPPRGLKMSSTFI 368
           +YLTVA +FRGRMSMKEVDEQML +Q+KNSSYFVEWIPNNVK AVCDIPPRGLKMSSTFI
Sbjct: 234 KYLTVAAMFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSSTFI 413

Query: 369 GNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQ 426
           GNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQ
Sbjct: 414 GNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQ 587
>25015
          Length = 458

 Score =  221 bits (563), Expect = 5e-58,   Method: Compositional matrix adjust.
 Identities = 101/115 (87%), Positives = 108/115 (93%)
 Frame = -3

Query: 20  FWEVISDEHGIDPSGNYVGDSDLQLERISVYYNEASSHKYVPRAILVDLEPGTMDSVRSG 79
           FWEVISDEHGIDP+G Y GDSDLQLERI+VYYNEA+  KYVPRA+LVDLEPGTMDSVRSG
Sbjct: 363 FWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEATGGKYVPRAVLVDLEPGTMDSVRSG 184

Query: 80  AFGHLFRPDNFIFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKECENCDCLQGFQ 134
            FG +FRPDNF+FGQSGAGNNWAKGHYTEGAELVDSVLDVVRKE E+CDCLQGFQ
Sbjct: 183 PFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEAESCDCLQGFQ 19
>39157
          Length = 488

 Score =  211 bits (537), Expect(2) = 9e-58,   Method: Compositional matrix adjust.
 Identities = 103/125 (82%), Positives = 113/125 (90%), Gaps = 3/125 (2%)
 Frame = -1

Query: 1   MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPSGNYVGDSDLQLERISVYYNEASSHKYV 60
           MREIVH+QAGQCGNQIGAKFWEVISDEHGIDP+G Y GDSDLQLERI+VYYNEA+  KYV
Sbjct: 443 MREIVHLQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEATGGKYV 264

Query: 61  PRAILVDLEPGTMDSVRSGA-FG-HLFRPDNFIFGQSGAGNNWAKGHYTE-GAELVDSVL 117
           PRA+LVDLEPGTMDSVRSG+ FG  +FRPDNF+FGQSGAGNNW +   T+ GAELVDSVL
Sbjct: 263 PRAVLVDLEPGTMDSVRSGSPFGPKIFRPDNFVFGQSGAGNNWGQKDTTQRGAELVDSVL 84

Query: 118 DVVRK 122
           DVVRK
Sbjct: 83  DVVRK 69

 Score = 30.8 bits (68), Expect(2) = 9e-58,   Method: Compositional matrix adjust.
 Identities = 11/13 (84%), Positives = 12/13 (92%)
 Frame = -2

Query: 122 KECENCDCLQGFQ 134
           KE E+CDCLQGFQ
Sbjct: 70  KEAESCDCLQGFQ 32
>12457
          Length = 781

 Score =  207 bits (526), Expect = 9e-54,   Method: Compositional matrix adjust.
 Identities = 97/239 (40%), Positives = 140/239 (58%)
 Frame = -1

Query: 65  LVDLEPGTMDSVRSGAFGHLFRPDNFIFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEC 124
           LVDLEP  +D VR+G +  LF P+  + G+  A NN+A+GHYT G E+VD VLD +RK  
Sbjct: 718 LVDLEPTVVDEVRTGTYRQLFHPEQLVTGKEDAANNYARGHYTIGKEIVDLVLDRIRKLA 539

Query: 125 ENCDCLQGFQXXXXXXXXXXXXXXXXXXXKVREEYPDRIMNTFSVVPSPKVSDTVVEPYN 184
           + C  LQGF                    ++  +Y  +    F++ P+P+VS  VVEPYN
Sbjct: 538 DQCTGLQGFLIFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFAIYPAPQVSTAVVEPYN 359

Query: 185 ATLSIHQLVENTDETYCIDNEALYDICFRTLKLATPTYGDLNHLVSATMSGVTTSLRFPG 244
           + L+ H  +E++D  + +DNEA+YDIC R L +  PTY +LN L+   +S +T SLRF G
Sbjct: 358 SILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLRFDG 179

Query: 245 QLNADLRKLAVNMVPFPRLHFFMPGFAPLTARGSQQYRALTVPELTQQMFDAKNMMAAC 303
            LN DL +   N+VP+PR+HF +  +AP+ +     +  LTV E+T   F+  N M  C
Sbjct: 178 ALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLTVAEITNACFEPANQMVKC 2
>05902
          Length = 1127

 Score =  157 bits (396), Expect = 1e-38,   Method: Compositional matrix adjust.
 Identities = 93/282 (32%), Positives = 159/282 (56%), Gaps = 12/282 (4%)
 Frame = +2

Query: 154 KVREEYPDRIMNTFSVVPS-PKVSDTVVEPYNATLSIHQLVENTDETYCIDNEALYDICF 212
           K+ + +P +++ T+SV P+  ++SD VV+PYN+ L++ +L +N D    +DN AL  I  
Sbjct: 74  KLNDRFPKKLIQTYSVFPNVDEISDVVVQPYNSLLTLKRLTQNADCVVVLDNTALNRIAA 253

Query: 213 RTLKLATPTYGDLNHLVSATMSGVTTSLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAP 272
             L + TPT+  +N LVS  MS  TT+LR+PG +N DL  L  +++P PRLHF M G+ P
Sbjct: 254 DRLHIDTPTFAQVNQLVSTVMSTSTTTLRYPGYMNNDLIGLIASLIPTPRLHFLMTGYTP 433

Query: 273 LTARGS-QQYRALTVPELTQQMFDAKNMMAACDPRHGR----YLTVATVFRGRMSMKEVD 327
           LT        R  TV ++ +++   KNMM +  P H +    Y+++  + +G +   +V 
Sbjct: 434 LTTDSQVANVRKTTVLDVMRRLLQPKNMMVST-PVHRQANHCYISILNIIQGEVDPTQVH 610

Query: 328 EQMLAIQSKNSSYFVEWIPNNVKVAVCDIPP---RGLKMSSTFIGNSTAIQELFKRISEQ 384
           + +  I+ +  + F+ W P +++VA+    P      ++S   + N T+I  LF+RI  Q
Sbjct: 611 KSLQRIRERKLAQFIPWGPASIQVALSRKSPYVQTAHRVSGLMLANHTSISHLFERILRQ 790

Query: 385 FTAMFRRKAFLHWYTGEGM--DEM-EFTEAESNMNDLVSEYQ 423
           +  + +R+AF+  +  E +  D + EF  +   +  LV EYQ
Sbjct: 791 YDKLRKREAFMDQFKKEAIFKDNLDEFDNSREALQLLVDEYQ 916
>06360
          Length = 1896

 Score =  131 bits (329), Expect = 6e-31,   Method: Compositional matrix adjust.
 Identities = 65/179 (36%), Positives = 97/179 (54%), Gaps = 2/179 (1%)
 Frame = -1

Query: 1    MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPSGNYVGDSDLQL--ERISVYYNEASSHK 58
            MRE + +  GQ G Q+G   WE+   EHGI P G    D  +    +  + +++E  + K
Sbjct: 1710 MRECISVHVGQAGVQMGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGK 1531

Query: 59   YVPRAILVDLEPGTMDSVRSGAFGHLFRPDNFIFGQSGAGNNWAKGHYTEGAELVDSVLD 118
            +VPRA+ VDLEP  +D VR+G +  LF P+  + G+  A NN+A+GHYT G E+VD VLD
Sbjct: 1530 HVPRAVFVDLEPTVVDEVRTGTYRQLFHPEQLVTGKEDAANNYARGHYTIGKEIVDLVLD 1351

Query: 119  VVRKECENCDCLQGFQXXXXXXXXXXXXXXXXXXXKVREEYPDRIMNTFSVVPSPKVSD 177
             +RK  + C  LQGF                    ++  +Y  +    F++ P+P+VSD
Sbjct: 1350 RIRKLADQCTGLQGFLIFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFAIYPAPQVSD 1174
>03702
          Length = 1932

 Score =  122 bits (305), Expect = 4e-28,   Method: Compositional matrix adjust.
 Identities = 59/140 (42%), Positives = 84/140 (60%), Gaps = 1/140 (0%)
 Frame = +1

Query: 167  FSVVPSPKVSDTVVEPYNATLSIHQLVENTDETYCIDNEALYDICFRTLKLATPTYGDLN 226
            F++ P+P+VS  VVEPYN+ L+ H  +E++D  + +DNEA+YDIC R L +  P Y +LN
Sbjct: 1501 FAIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPXYTNLN 1680

Query: 227  HLVSATMSGVTTSLRFPGQLNADLRKLAVNMVPFPRLHFFMPG-FAPLTARGSQQYRALT 285
             L+   +S +T SLRF G LN DL +   N+VP P  H   PG   P+ +     +  LT
Sbjct: 1681 RLIGQIVSSITASLRFDGALNVDLTEFQTNLVPTP--HPLPPGHLCPVISAEKAYHEQLT 1854

Query: 286  VPELTQQMFDAKNMMAACDP 305
            V E+T   F+  N +  CDP
Sbjct: 1855 VAEVTNACFEPANQLVKCDP 1914
>17215
          Length = 632

 Score = 83.2 bits (204), Expect = 2e-16,   Method: Compositional matrix adjust.
 Identities = 38/117 (32%), Positives = 68/117 (58%), Gaps = 8/117 (6%)
 Frame = +3

Query: 316 VFRGRMSMKEVDEQMLAIQSKNSSYFVEWIPNNVKVAVCDIPPR--------GLKMSSTF 367
           ++RG +  K+V+  +  I++K +  FV+W P   KV +   PP          ++ +   
Sbjct: 6   LYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCM 185

Query: 368 IGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQ 424
           + N+TAI E + R+  +F  M+ ++AF+HWY GEGM+E EF+EA  ++  L  +Y++
Sbjct: 186 LSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEE 356
>29025
          Length = 395

 Score = 33.5 bits (75), Expect = 0.17,   Method: Compositional matrix adjust.
 Identities = 15/15 (100%), Positives = 15/15 (100%)
 Frame = -3

Query: 412 ESNMNDLVSEYQQYQ 426
           ESNMNDLVSEYQQYQ
Sbjct: 354 ESNMNDLVSEYQQYQ 310
>24946
          Length = 955

 Score = 27.7 bits (60), Expect = 9.8,   Method: Compositional matrix adjust.
 Identities = 10/29 (34%), Positives = 20/29 (68%), Gaps = 2/29 (6%)
 Frame = +3

Query: 330 MLAIQSKNSSYFV--EWIPNNVKVAVCDI 356
           +++I  K+ S F+  +W+PN+V +  CD+
Sbjct: 798 VMSIDGKHFSVFLILDWVPNSVHINFCDV 884
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|42475974|ref|NP_852079.2| phosphoinositide-3-kinase,
class 3 [Mus musculus]
         (887 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

14901                                                                 429   e-125
05967                                                                 312   4e-85
34349                                                                 158   1e-38
06655                                                                  94   2e-19
18761                                                                  68   1e-11
12508                                                                  43   5e-04
18312                                                                  43   6e-04
28814                                                                  40   0.003
26068                                                                  40   0.003
11201                                                                  31   2.1  
11722                                                                  29   7.7  
>14901
          Length = 1135

 Score =  429 bits (1103), Expect(3) = e-125,   Method: Compositional matrix adjust.
 Identities = 193/322 (59%), Positives = 252/322 (78%), Gaps = 1/322 (0%)
 Frame = -3

Query: 22   KIGSLEGKREQKSYKAVLEDPMLKFSGLYQ-ETCSDLYVTCQVFAEGKPLALPVRTSYKA 80
            KIG+LEG+R + S K + E+P  +FSG YQ E  +DLYVTCQVF++G+ + LPV+T YKA
Sbjct: 1037 KIGTLEGERPRYSLKELREEPAKRFSGAYQREGNADLYVTCQVFSDGRSMGLPVQTCYKA 858

Query: 81   FSTRWNWNEWLKLPVKYPDLPRNAQVALTIWDVYGPGSAVPVGGTTVSLFGKYGMFRQGM 140
            FS+RWNWNEW++LP+++  LPRNA +ALTIWD+ G   AVPVGGT++ LF K G  R+GM
Sbjct: 857  FSSRWNWNEWIQLPIQFSSLPRNAVLALTIWDIEGNFKAVPVGGTSIKLFSKRGKLRKGM 678

Query: 141  HDLKVWPNVEADGSEPTRTPGRTSSTLSEDQMSRLAKLTKAHRQGHMVKVDWLDRLTFRE 200
            HDL+VWP V  DGS+ ++TPG+  +    D M RL+K+TK HR GHM+K DWLDRL+FRE
Sbjct: 677  HDLRVWPRVVGDGSDASKTPGKAKTN---DLMDRLSKMTKKHRNGHMIKCDWLDRLSFRE 507

Query: 201  IEMINESEKRSSNFMYLMVEFRCVKCDDKEYGIVYYEKDGDESSPILTSFELVKVPDPQM 260
            IEMINE +KR +NFMYLM+EF  +  D++EY +VY+EKDGD+        +LV +PDP M
Sbjct: 506  IEMINERQKRETNFMYLMIEFPQITYDNQEYTVVYFEKDGDKGYEFRQIADLVTIPDPDM 327

Query: 261  SMENLVESKHHKLARSLRSGPSDHDLKPNATTRDQLNIIVSYPPTKQLTYEEQDLVWKFR 320
             +ENL E+KHHK+ARSLRSGP D D+KP+A TRD L  IV+YPPT Q++ EE+DL+WKFR
Sbjct: 326  LLENLYEAKHHKMARSLRSGPRDRDMKPDAKTRDMLKKIVAYPPTTQMSSEEEDLIWKFR 147

Query: 321  YYLTNQEKALTKFLKCVNWDLP 342
            +YL+ Q++ALTKFLKCVNW +P
Sbjct: 146  FYLSTQKEALTKFLKCVNWKVP 81

 Score = 36.6 bits (83), Expect(3) = e-125,   Method: Compositional matrix adjust.
 Identities = 12/19 (63%), Positives = 18/19 (94%)
 Frame = -1

Query: 4    AEKFHYIYSCDLDINVQLK 22
            +++FHY+YSCDLD N+Q+K
Sbjct: 1090 SDRFHYLYSCDLDFNLQIK 1034

 Score = 26.2 bits (56), Expect(3) = e-125,   Method: Composition-based stats.
 Identities = 10/17 (58%), Positives = 14/17 (82%)
 Frame = -2

Query: 344 EAKQALELLGKWKPMDV 360
           EAKQA EL+ +W+ +DV
Sbjct: 78  EAKQATELMVRWQAVDV 28
>05967
          Length = 1076

 Score =  312 bits (800), Expect = 4e-85,   Method: Compositional matrix adjust.
 Identities = 168/351 (47%), Positives = 219/351 (62%), Gaps = 7/351 (1%)
 Frame = -1

Query: 238  KDGDESSPILTSFELVKVPDPQMSMENLVESKHHKLARSLRSGPSDHDLKPNATTRDQLN 297
            +DGD+        +LV +PDP M +ENL E+KHHK+ARSLRSGP D D+KP+A TRD L 
Sbjct: 1061 RDGDKGYEFRQIADLVTIPDPDMLLENLYEAKHHKMARSLRSGPRDRDMKPDAKTRDMLK 882

Query: 298  IIVSYPPTKQLTYEEQDLVWKFRYYLTNQEKALTKFLKCVNWDLPQEAKQALELLGKWKP 357
             IV+YPPT Q++ EE+DL+WKFR+YL+ Q++ALTKFLKCVNW +P EAKQA EL+ +W+ 
Sbjct: 881  KIVAYPPTTQMSSEEEDLIWKFRFYLSTQKEALTKFLKCVNWKVPLEAKQATELMVRWQA 702

Query: 358  MDVEDSLELLSSHYTNPTVRRYAVARLRQADDEDXXXXXXXXXXXXKYENFDDIKNGLE- 416
            +DV D+LELLS  +TNP VR+YAV+RL  ADDED            KYENF++IK+ +E 
Sbjct: 701  VDVVDALELLSPAFTNPLVRKYAVSRLEMADDEDLLLYLLQLLQALKYENFNEIKSKVED 522

Query: 417  -----PTKKDSQTXXXXXXXXXXXXXGDIDSSQIITNXXXXXXXXXXXXXXXXXXDGENL 471
                 P +  S+                  SS  IT+                       
Sbjct: 521  APPVPPPQTVSEDNPSPERERSSSSVSRTSSSDSITDALSAAPSRPDTASSTTKLGS--- 351

Query: 472  EQDLCTFLISRACKNSTLANYLYWYVIVECEDQ-DTQQRDPKTHEMYLNVMRRFSQALLK 530
            + DL TFLISRAC N  LANY +WY+ VECE+Q D Q R  +  EMY+ VM+RFS AL +
Sbjct: 350  QMDLATFLISRACNNPVLANYFFWYLSVECEEQPDNQSRYEQAREMYVCVMKRFSNALKQ 171

Query: 531  GDKSVRVMRSLLAAQQTFVDRLVHLMKAVQRESGNRKKKNERLQALLGDNE 581
                   MRS+L  Q+ F++ +V ++K V RESG+R KK E+LQALL D E
Sbjct: 170  QSCH---MRSVLTTQKNFLENIVQMVKIVTRESGSRSKKIEKLQALLHDPE 27
>34349
          Length = 413

 Score =  158 bits (399), Expect = 1e-38,   Method: Composition-based stats.
 Identities = 71/97 (73%), Positives = 80/97 (82%)
 Frame = +2

Query: 740 GVGDRHLDNLLLTKTGKLFHIDFGYILGRDXXXXXXXXXXNKEMVEGMGGTQSEQYQEFR 799
           GVGDRHLDNLLLT  GKLFHIDFGYILGRD          +KEMVE MGG  S+ Y EFR
Sbjct: 2   GVGDRHLDNLLLTTNGKLFHIDFGYILGRDPKPMPPPMKLSKEMVEAMGGVSSDHYHEFR 181

Query: 800 KQCYTAFLHLRRYSNLILNLFSLMVDANIPDIALEPD 836
           KQCYTA+LHLRR++N++LNLFSLMVDA++PDIALEPD
Sbjct: 182 KQCYTAYLHLRRHANVMLNLFSLMVDASVPDIALEPD 292

 Score = 54.7 bits (130), Expect = 1e-07,   Method: Composition-based stats.
 Identities = 24/39 (61%), Positives = 30/39 (76%)
 Frame = -2

Query: 108 LTIWDVYGPGSAVPVGGTTVSLFGKYGMFRQGMHDLKVW 146
           LTI+DV   G    +GGT +S+FGK GMFRQGM+DL+VW
Sbjct: 400 LTIFDVRA-GQTTVIGGTAISMFGKDGMFRQGMYDLRVW 287
>06655
          Length = 1350

 Score = 94.0 bits (232), Expect = 2e-19,   Method: Compositional matrix adjust.
 Identities = 52/173 (30%), Positives = 99/173 (57%), Gaps = 5/173 (2%)
 Frame = -2

Query: 703  FFRKYAPSETGPYGISAEVMDTYVKSCAGYCVITYILGVGDRHLDNLLLTKTGKLFHIDF 762
            F  ++ PS +  + ++A+    +V+SCAGYC++ Y++ V DRH  N+LL   G + HIDF
Sbjct: 1316 FVHEFGPSNSEEF-LTAQ--KNFVQSCAGYCLVCYLMQVKDRHNGNILLDAEGHIIHIDF 1146

Query: 763  GYIL----GRDXXXXXXXXXXNKEMVEGMGGTQSEQYQEFRKQCYTAFLHLRRYSNLILN 818
            G+IL    G++            E VE MGG  S+ ++ F+      F+  R++ + IL 
Sbjct: 1145 GFILSTSPGKNLGFENSPFKLTTEFVEVMGGQGSDMFEYFKILMLQGFVASRKHMDQILP 966

Query: 819  LFSLM-VDANIPDIALEPDKTVKKVQDKFRLDLSDEEAVHYMQSLIDESVHAL 870
            L  +M   + +P  + +   TV+ ++D+F +++++E+    + +L++ S+H+L
Sbjct: 965  LVEIMQTGSQLPCFS-KGVSTVRGLKDRFHMNMTEEQLQLLVDNLVESSLHSL 810
>18761
          Length = 492

 Score = 68.2 bits (165), Expect = 1e-11,   Method: Composition-based stats.
 Identities = 45/150 (30%), Positives = 72/150 (48%), Gaps = 7/150 (4%)
 Frame = +3

Query: 741 VGDRHLDNLLLTKTGKLFHIDFGYILGR-----DXXXXXXXXXXNKEMVEGM--GGTQSE 793
           +GDRH DN++L ++G +FHIDF   LG      +            +MV  +  GG Q  
Sbjct: 3   IGDRHNDNIMLKQSGHMFHIDFSKFLGDAQMFGNIKRDRVPFVLTPDMVFVINDGGKQGN 182

Query: 794 QYQEFRKQCYTAFLHLRRYSNLILNLFSLMVDANIPDIALEPDKTVKKVQDKFRLDLSDE 853
           ++Q+F   C  AF  LR +++L  NLF LM  + IP +    ++ V  +Q       +  
Sbjct: 183 RFQQFIDLCCQAFNILRTHADLFRNLFMLMSRSGIPGVT---EQAVTYIQRALLPGYTKA 353

Query: 854 EAVHYMQSLIDESVHALFAAVVEQIHKFAQ 883
           +A      +I++S+ +L       IH  AQ
Sbjct: 354 QASAAFTRMIEDSMRSLSTQFNFFIHNLAQ 443
>12508
          Length = 550

 Score = 43.1 bits (100), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 26/108 (24%), Positives = 49/108 (45%), Gaps = 5/108 (4%)
 Frame = +3

Query: 308 LTYEEQDLVWKFRYYLTNQEKALTKFLKC-----VNWDLPQEAKQALELLGKWKPMDVED 362
           LT EE +++W +R+YL ++  AL + L+       +W    + +    LL  W P+    
Sbjct: 231 LTAEEMEIIWTYRHYLYSKPTALPRILQAKGAHGWHWSSLPDLRS---LLSLWPPLHPTQ 401

Query: 363 SLELLSSHYTNPTVRRYAVARLRQADDEDXXXXXXXXXXXXKYENFDD 410
           + E+L   Y +  VR +A   L +   +D            K+E++ +
Sbjct: 402 AFEILLPQYPDLGVREFAAESLARIPADDLAHFLPQLIQALKFESYHN 545
>18312
          Length = 560

 Score = 43.1 bits (100), Expect = 6e-04,   Method: Composition-based stats.
 Identities = 20/45 (44%), Positives = 29/45 (64%), Gaps = 1/45 (2%)
 Frame = -3

Query: 725 YVKSCAGYCVITYILGVGDRHLDNLLL-TKTGKLFHIDFGYILGR 768
           Y +S A   ++ YILG+GDRH+ N+L+   T +L HID G  L +
Sbjct: 150 YTRSVATNSIVGYILGLGDRHVMNILIDCVTAELIHIDLGIALNK 16
>28814
          Length = 372

 Score = 40.4 bits (93), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 25/83 (30%), Positives = 42/83 (50%), Gaps = 4/83 (4%)
 Frame = -3

Query: 618 PAQLFFKTEDGGKYPVIFKHGDDLRQDQLILQIISLMDKLLRKE----NLDLKLTPYKVL 673
           P +L     DG +Y  + K  +DLRQD+ ++Q+  L++ LLR        +L +T +  +
Sbjct: 352 PRKLSIFGSDGKEYQFLLKGHEDLRQDERVMQLFGLVNSLLRNNADTFRRNLTITRFAAI 173

Query: 674 ATSTKHGFMQFIQSVPVAEVLDT 696
             ST  G + +   VP  + L T
Sbjct: 172 PLSTNSGLIGW---VPHCDTLHT 113
>26068
          Length = 460

 Score = 40.4 bits (93), Expect = 0.003,   Method: Composition-based stats.
 Identities = 17/30 (56%), Positives = 25/30 (83%), Gaps = 1/30 (3%)
 Frame = +2

Query: 734 VITYILGVGDRHLDNLLLT-KTGKLFHIDF 762
           +I YI+G+GDRHLDN+L+   TG++ HID+
Sbjct: 2   MIGYIIGLGDRHLDNVLVDLATGEVVHIDY 91
>11201
          Length = 916

 Score = 31.2 bits (69), Expect = 2.1,   Method: Composition-based stats.
 Identities = 18/54 (33%), Positives = 24/54 (44%)
 Frame = -3

Query: 325 NQEKALTKFLKCVNWDLPQEAKQALELLGKWKPMDVEDSLELLSSHYTNPTVRR 378
           N   A      C N  L + + Q + LLG +   DV   L  L  H T+PT R+
Sbjct: 218 NNSIAADHIADCYNRSLNRSSDQPVLLLGDFNTCDVSKHLPHLYQHVTHPTRRQ 57
>11722
          Length = 814

 Score = 29.3 bits (64), Expect = 7.7,   Method: Composition-based stats.
 Identities = 26/102 (25%), Positives = 44/102 (43%), Gaps = 1/102 (0%)
 Frame = +3

Query: 278 RSGPSDHDLKPNATTRDQLNIIVSYPPTKQLTYEEQDLVWKFRYYL-TNQEKALTKFLKC 336
           ++  +++ ++   +T+D   + VS+ P   L  E   L     Y    N   A      C
Sbjct: 456 KTWATNYTVRETVSTKDFELLCVSFRP-HYLPREFSQLTVILVYVPGPNNSIAADHIADC 632

Query: 337 VNWDLPQEAKQALELLGKWKPMDVEDSLELLSSHYTNPTVRR 378
            N  L + + Q + LLG +   DV   L  L  + T+PT R+
Sbjct: 633 YNRSLNRSSDQPVLLLGDFNTCDVSKHLPHLYQYVTHPTRRQ 758
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|112807186|ref|NP_766307.2| GCN1 general control of
amino-acid synthesis 1-like 1 [Mus musculus]
         (2671 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

10671                                                                 375   e-124
30928                                                                 166   5e-41
14383                                                                  44   7e-04
25535                                                                  34   0.75 
>10671
          Length = 1836

 Score =  375 bits (964), Expect(2) = e-124,   Method: Compositional matrix adjust.
 Identities = 191/437 (43%), Positives = 282/437 (64%), Gaps = 1/437 (0%)
 Frame = -2

Query: 180  VEQYFSAILSLEPSQNYAAMLGLLVQFCTNHKEMDAVSQHKSTLLEFYVKNILMSKAKPP 239
            +E+Y   +  +EPS      +G ++Q+ +  K    + ++K   LE Y+K +L S+  PP
Sbjct: 1832 LEKYLCFMEKVEPSVFNTCCMGCVLQYLSATKNKALLDKYKGAYLELYLKQVLASRTTPP 1653

Query: 240  KYLLDNCAPLLRFMSHSEFKDLILPTIQKSLLRSPENVIETISSLLASVTLDLSQYALDI 299
              +L +   +LR  +H EFK  +LP  QK++LR+PE ++ T+  +L+ +++DLSQYA D+
Sbjct: 1652 LSVLVSSQEILRHCNHEEFKGQVLPAAQKAMLRNPEVILSTVGRMLSQLSVDLSQYAGDL 1473

Query: 300  VKGLANQLKSNSPRLMDEAVLALRNLARQCSDSSATEALTKHLFAILGGSEGKLTIIAQK 359
             K L  Q+ S       EAV+ ++NLA QCSD  A E L KH F +L GSEGKLT++ QK
Sbjct: 1472 GKLLGAQIVSKDEGTRKEAVVGVKNLAVQCSDPGAVEKLVKHFFGVLNGSEGKLTVVDQK 1293

Query: 360  MSVLSGIGSLSHHVVSGPSG-QVLNGCVAELFIPFLQQEVHEGTLVHAVSILALWCNRFT 418
            MSVL G+G+L ++ VSG +  Q L   VA+LF+P LQQEVHEGTLVH +++L+LWC++F 
Sbjct: 1292 MSVLQGVGNLFYNTVSGTASLQDLASKVADLFLPTLQQEVHEGTLVHTLAMLSLWCSKFY 1113

Query: 419  TEVPKKLTDWFKKVFSLKTSTSAVRHAYLQCMLASFRGDTLLQALDFLPLLMQTVEKAAS 478
            T VP KL  WF+K  +LK+STSAVR+AY  C+ A F GDT+ QA   +PLL+QT+EK   
Sbjct: 1112 TAVPDKLLLWFEKGLTLKSSTSAVRNAYFLCINACFHGDTMQQATRVVPLLLQTLEKGGK 933

Query: 479  QGTQVPTVTEGXXXXXXXXXXXXXDAQAEAKLSGFWQLVVDEKRQTFTSEKFLLLASEDA 538
            Q +Q+  VTE              D +A++K+  FW +V++  +Q F S+KFL  AS++ 
Sbjct: 932  QPSQLNLVTEVVSTSRTLVRLASVDIEADSKMGPFWSMVLEPSKQWFLSDKFLGSASDET 753

Query: 539  LCTVLRLTERLFLDHPHRLTNSKVQQYYRVLVAVLLSRTWHVRRQAQQTVRKLLSSLGGV 598
            LC+++ +TERL +D P+++T +  + YYR LV  L  R+W VR     TVRKLL+ LGG 
Sbjct: 752  LCSMVAVTERLVMDFPNKMTEAVSRPYYRALVFCLTRRSWTVRGPTITTVRKLLAMLGGA 573

Query: 599  KLANGLLDELKTVLNSH 615
            ++A  L+DE K +L + 
Sbjct: 572  QIALALIDEFKAILATQ 522

 Score = 92.4 bits (228), Expect(2) = e-124,   Method: Compositional matrix adjust.
 Identities = 47/149 (31%), Positives = 84/149 (56%)
 Frame = -1

Query: 638 VPPRVLQEALCVISGVPGLKGDIPSTEQLAQEMLIISHHPSLVAVQSGLWPALLTRMKID 697
           + P++L  AL  +  V   K D    E +A   L+ +HHP ++     +W  ++ R+ + 
Sbjct: 453 ITPKILCSALLAVCSVE--KVDTRDAEAIAMATLLPAHHPYIMYSNQDMWVEIIQRLNLQ 280

Query: 698 PDAFITRHLDQIIPRITTQSPLNQSSMNAMGSLSVLSPDRVLPQLISTITASVQNPALCL 757
           P  F+ +H+DQ +    T + L ++   A+ ++  + P+ V+P +IS +T+ + N  L  
Sbjct: 279 PHKFVEKHVDQCLAFAKTGNILPENVKKAVETVCRVCPESVVPSVISYVTSLLSNTGLEQ 100

Query: 758 VTREEFSIMQTPAGELFDKSIIQSAQQDS 786
           +TREE+ I  TP GEL+D+SII +A + S
Sbjct: 99  ITREEYGIFLTPEGELYDRSIIDNAMKTS 13
>30928
          Length = 343

 Score =  166 bits (420), Expect(2) = 5e-41,   Method: Composition-based stats.
 Identities = 77/103 (74%), Positives = 89/103 (86%)
 Frame = +2

Query: 1750 PHVRDGYIMMFNYLPITFGDKFTPYVGPIIPCILKALADENEFVRDTALRAGQRVISMYA 1809
            P VRDGYIM + YLP  FG  F  YVGPI+P IL+ALADE+EFVRDTALRAGQR+IS YA
Sbjct: 5    PSVRDGYIMTYIYLPAVFGTDFAQYVGPILPSILQALADESEFVRDTALRAGQRIISQYA 184

Query: 1810 ETAIALLLPQLEQGLFDDLWRIRFSSVQLLGDLLFHISGVTGK 1852
            +TAI LLLP+LE+GLFDD WRIR+SSVQLLGDLL+ +SGV+GK
Sbjct: 185  DTAIELLLPELERGLFDDNWRIRYSSVQLLGDLLYKVSGVSGK 313

 Score = 22.7 bits (47), Expect(2) = 5e-41,   Method: Compositional matrix adjust.
 Identities = 9/14 (64%), Positives = 10/14 (71%)
 Frame = +3

Query: 1848 GVTGKMTTETASED 1861
            G   +MTTETA ED
Sbjct: 300  GCLARMTTETADED 341

 Score = 40.8 bits (94), Expect = 0.008,   Method: Composition-based stats.
 Identities = 22/92 (23%), Positives = 40/92 (43%)
 Frame = +2

Query: 1435 REGALFAFEMLCTMLGKLFEPYXXXXXXXXXXCFGDGNQYVREAADDCAKAVMSNLSAHG 1494
            R+G +  +  L  + G  F  Y             D +++VR+ A    + ++S  +   
Sbjct: 14   RDGYIMTYIYLPAVFGTDFAQYVGPILPSILQALADESEFVRDTALRAGQRIISQYADTA 193

Query: 1495 VKLVLPXXXXXXXXXXWRTKAGSVELLGAMAY 1526
            ++L+LP          WR +  SV+LLG + Y
Sbjct: 194  IELLLPELERGLFDDNWRIRYSSVQLLGDLLY 289
>14383
          Length = 710

 Score = 44.3 bits (103), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 53/217 (24%), Positives = 94/217 (43%), Gaps = 14/217 (6%)
 Frame = +2

Query: 1646 TDQKDLAPYLPSVTPGLKASLLDPVPEVRTVSAKALGAMV---KGMGESCFEDLLPWLME 1702
            T ++ LAPY+  + P L     DP P ++   A    A+V   K   ++  +++L  L++
Sbjct: 35   TSREQLAPYMSQIVPRLYRYQFDPNPRIQQAMAGIWSALVTDNKKTVDTYLKEILHDLLK 214

Query: 1703 TLTYEQSSVDRSGAAQGLAEVMAGLGVEKLEKLMPEIVATASKV--DIAPHVR---DGYI 1757
             LT  Q  V R  +   + +++ G  ++ + + +PE+     +V  DI   VR   D   
Sbjct: 215  NLTNNQWRV-RESSCNAVTDLLRGRTLDTIVEDLPELWEQCLRVRDDIKESVRLSADQSC 391

Query: 1758 MMFNYLPITFGDKFTPYVG-----PIIPCILKALADENEFVRDTALRA-GQRVISMYAET 1811
               + + I   D      G      ++PC+L    + N  V++  +RA G   I   ++ 
Sbjct: 392  KTLSKVSIRICDPENGQAGERATSAVLPCLLNITLNTN--VKE--VRAIGLSTILEISKK 559

Query: 1812 AIALLLPQLEQGLFDDLWRIRFSSVQLLGDLLFHISG 1848
            A  LL P +   +   L  +     Q+L  L FH S 
Sbjct: 560  AGKLLKPHIHTLVVALLEAVSGLEPQVLNYLSFHTSS 670
>25535
          Length = 437

 Score = 34.3 bits (77), Expect = 0.75,   Method: Composition-based stats.
 Identities = 22/74 (29%), Positives = 38/74 (51%), Gaps = 7/74 (9%)
 Frame = -1

Query: 172 LWKENPGLVEQYFSAILSLEP-------SQNYAAMLGLLVQFCTNHKEMDAVSQHKSTLL 224
           L K++PG+V+QY   +LS E           +  ML  L+   +N  E + +++H     
Sbjct: 281 LAKKDPGIVKQYERGMLSEETLMKSDTFENMFGGMLKGLIAATSNWSEYENITKHLQRFS 102

Query: 225 EFYVKNILMSKAKP 238
           + + K IL++ AKP
Sbjct: 101 DSFRK-ILLAAAKP 63
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|22122615|ref|NP_666219.1| ARP1 actin-related protein
1 homolog B, centractin beta [Mus musculus]
         (376 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

04742                                                                 439   e-124
12322                                                                 376   e-105
39562                                                                 356   7e-99
02757                                                                 139   2e-63
00608                                                                 179   2e-45
32273                                                                 176   1e-44
01436                                                                 129   2e-30
19721                                                                  92   3e-30
36954                                                                 119   3e-27
11487                                                                  67   3e-20
18926                                                                  95   5e-20
13361                                                                  90   2e-18
26639                                                                  30   1.1  
14855                                                                  28   7.0  
>04742
          Length = 2111

 Score =  439 bits (1129), Expect = e-124,   Method: Compositional matrix adjust.
 Identities = 200/369 (54%), Positives = 275/369 (74%), Gaps = 4/369 (1%)
 Frame = +2

Query: 12  VVIDNGSGVIKAGFAGDQIPKYCFPNYVGRPKHMRVMAGALEGDLFIGPKAEEHRGLLTI 71
           +VIDNGSG+ KAGFAGD  P+  FP+ VGRP+H  VM G  + D ++G +A+  RG+LT+
Sbjct: 116 LVIDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTL 295

Query: 72  RYPMEHGVVRDWNDMERIWQYVYSKDQLQTFSEEHPVLLTEAPLNPSKNREKAAEVFFET 131
           +YP+EHG+V +W+DME+IW + +  ++L+   EEHPVLLTEAPLNP  NREK  ++ FET
Sbjct: 296 KYPIEHGIVTNWDDMEKIWHHTF-YNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFET 472

Query: 132 FNVPALFISMQAVLSLYATGRTTGVVLDSGDGVTHAVPIYEGFAMPHSIMRVDIAGRDVS 191
           FN PA+++++QAVLSLYA+GRTTG+VLDSGDGV H VPIYEG+A+PH+I R+D+AGRD++
Sbjct: 473 FNSPAMYVAIQAVLSLYASGRTTGIVLDSGDGVXHTVPIYEGYALPHAISRLDLAGRDLT 652

Query: 192 RYLRLLLRKEGADFHTSAEFEVVRTIKERACYLSINPQKD--EALETEKVQ--YTLPDGS 247
            YL  +L + G  F T+AE E+VR IKE+ CY++++ +++   A  +  ++  Y LPDG 
Sbjct: 653 DYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMQTAASSSSLEKSYELPDGQ 832

Query: 248 TLDVGPARFRAPELLFQPDLVGDESEGLHEVLAFAIHKSDMDLRRTLFSNIVLSGGSTLF 307
            + +G  RFR PE +FQP  +G ES G HE    +I K D+D+R+ L++N VLSGGST++
Sbjct: 833 VITIGNERFRCPEAMFQPSFLGMESAGXHETTYNSIMKCDVDIRKDLYANTVLSGGSTMY 1012

Query: 308 KGFGDRLLSEVKKLAPKDVKIKISAPQERLYSTWIGGSILASLDTFKKMWVSKKEYEEDG 367
            G  DR+  E+  LAP  +KIKI AP ER YS WIGGSILASL TF++MW+SK+EY+E G
Sbjct: 1013PGIADRMQKEITALAPPTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESG 1192

Query: 368 SRAIHRKTF 376
              +HRK F
Sbjct: 1193PSIVHRKCF 1219
>12322
          Length = 849

 Score =  376 bits (965), Expect = e-105,   Method: Compositional matrix adjust.
 Identities = 173/213 (81%), Positives = 202/213 (94%)
 Frame = +1

Query: 164 VTHAVPIYEGFAMPHSIMRVDIAGRDVSRYLRLLLRKEGADFHTSAEFEVVRTIKERACY 223
           VTHAVP+YEGFAMPHSIMRVD+AGRDV+RYLRLLLRKEG D HT+AEFEVV+ IKER CY
Sbjct: 1   VTHAVPVYEGFAMPHSIMRVDVAGRDVTRYLRLLLRKEGMDLHTTAEFEVVKHIKERTCY 180

Query: 224 LSINPQKDEALETEKVQYTLPDGSTLDVGPARFRAPELLFQPDLVGDESEGLHEVLAFAI 283
           LSINP K+E+++TEKV YTLPDG+T++VGPARFRAPELLF+PDL+G+E EG+HEVL+++I
Sbjct: 181 LSINPLKEESVDTEKVSYTLPDGNTVEVGPARFRAPELLFRPDLIGEECEGIHEVLSYSI 360

Query: 284 HKSDMDLRRTLFSNIVLSGGSTLFKGFGDRLLSEVKKLAPKDVKIKISAPQERLYSTWIG 343
            KSD+DLR+TL+SNIVLSGGSTLFKGFGDRLLSE+KKLAPKD+KI+ISAPQERLYSTWIG
Sbjct: 361 QKSDVDLRKTLYSNIVLSGGSTLFKGFGDRLLSELKKLAPKDIKIRISAPQERLYSTWIG 540

Query: 344 GSILASLDTFKKMWVSKKEYEEDGSRAIHRKTF 376
            SILASLDTF+KMWVSK+EY E+G +AIHRKTF
Sbjct: 541 XSILASLDTFRKMWVSKREYHEEGVKAIHRKTF 639
>39562
          Length = 1438

 Score =  356 bits (914), Expect = 7e-99,   Method: Compositional matrix adjust.
 Identities = 164/302 (54%), Positives = 226/302 (74%), Gaps = 4/302 (1%)
 Frame = -2

Query: 79   VVRDWNDMERIWQYVYSKDQLQTFSEEHPVLLTEAPLNPSKNREKAAEVFFETFNVPALF 138
            +V +W+DME+IW + +  ++L+   EEHPVLLTEAPLNP  NREK  ++ FETFN PA++
Sbjct: 1437 IVTNWDDMEKIWHHTF-YNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNSPAMY 1261

Query: 139  ISMQAVLSLYATGRTTGVVLDSGDGVTHAVPIYEGFAMPHSIMRVDIAGRDVSRYLRLLL 198
            +++QAVLSLYA+GRTTG+VLDSGDGVTH VPIYEG+A+PH+IMR+D+AGRD++ YL  +L
Sbjct: 1260 VAIQAVLSLYASGRTTGIVLDSGDGVTHTVPIYEGYALPHAIMRLDLAGRDLTDYLMKIL 1081

Query: 199  RKEGADFHTSAEFEVVRTIKERACYLSINPQKD--EALETEKVQ--YTLPDGSTLDVGPA 254
             + G  F T+AE E+VR IKE+  Y++++ +++   A  +  ++  Y LPDG  + +G  
Sbjct: 1080 TERGYSFTTTAEREIVRDIKEKLDYVALDFEQEMLTAASSSSLEKSYELPDGQVITIGNE 901

Query: 255  RFRAPELLFQPDLVGDESEGLHEVLAFAIHKSDMDLRRTLFSNIVLSGGSTLFKGFGDRL 314
            RFR PE +FQP  +G ES G+HE    +I K D+D+R+ L++N VLSGGST++ G  DR+
Sbjct: 900  RFRCPEAMFQPSFLGMESAGIHETTYNSIMKCDVDIRKDLYANTVLSGGSTMYPGIADRM 721

Query: 315  LSEVKKLAPKDVKIKISAPQERLYSTWIGGSILASLDTFKKMWVSKKEYEEDGSRAIHRK 374
              E+  LAP  +KIKI AP ER YS WIGGSILASL TF++MW+SK+EY+E G   +HRK
Sbjct: 720  QKEITALAPPTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRK 541

Query: 375  TF 376
             F
Sbjct: 540  CF 535
>02757
          Length = 1094

 Score =  139 bits (351), Expect(3) = 2e-63,   Method: Compositional matrix adjust.
 Identities = 66/152 (43%), Positives = 99/152 (65%), Gaps = 4/152 (2%)
 Frame = -2

Query: 177 PHSIMRVDIAGRDVSRYLRLLLRKEGADFHTSAEFEVVRTIKERACYLSINPQKDEALET 236
           P +I+R+D+AGRD++ YL  +L + G  F T+AE E+V  IKE+ CY++++ +++ A   
Sbjct: 997 PTAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVXDIKEKLCYVALDFEQEMATAA 818

Query: 237 EKVQ----YTLPDGSTLDVGPARFRAPELLFQPDLVGDESEGLHEVLAFAIHKSDMDLRR 292
                   Y LPDG  + +G  RFR PE LFQP  +G ES G+HE    +I K D+D+R+
Sbjct: 817 SSSSLEKSYELPDGQVITIGNERFRCPESLFQPSFLGMESAGIHETTYNSIMKCDVDIRK 638

Query: 293 TLFSNIVLSGGSTLFKGFGDRLLSEVKKLAPK 324
            L++N VLSGG+T+F G  DR+  E+  LAP+
Sbjct: 637 DLYANTVLSGGTTMFPGIADRMQKEITALAPQ 542

 Score = 75.5 bits (184), Expect(3) = 2e-63,   Method: Compositional matrix adjust.
 Identities = 33/51 (64%), Positives = 40/51 (78%)
 Frame = -3

Query: 326 VKIKISAPQERLYSTWIGGSILASLDTFKKMWVSKKEYEEDGSRAIHRKTF 376
           +KIK  AP ER YS WIGGSILASL TF++MW+SK+EY+E G   +HRK F
Sbjct: 537 MKIKXIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF 385

 Score = 67.0 bits (162), Expect(3) = 2e-63,   Method: Compositional matrix adjust.
 Identities = 29/34 (85%), Positives = 33/34 (97%)
 Frame = -1

Query: 145  LSLYATGRTTGVVLDSGDGVTHAVPIYEGFAMPH 178
            LSLYA+GRTTG+VLDSGDGVTH VPIYEG+A+PH
Sbjct: 1094 LSLYASGRTTGIVLDSGDGVTHTVPIYEGYALPH 993
>00608
          Length = 1930

 Score =  179 bits (454), Expect = 2e-45,   Method: Compositional matrix adjust.
 Identities = 113/324 (34%), Positives = 181/324 (55%), Gaps = 35/324 (10%)
 Frame = +3

Query: 79  VVRDWNDMERIWQYVYSKDQLQTFSEEHPVLLTEAPLNPSKNREKAAEVFFETFNVPALF 138
           ++ DW+ MER ++ V  K  L+   E+H  LLTE PLN  +NRE  AE+ FE+FNVP L+
Sbjct: 3   IIDDWDLMERFYEQVIFK-YLRAEPEDHYFLLTEPPLNTPENREYTAEIMFESFNVPGLY 179

Query: 139 ISMQAVLSLYATGRT--------TGVVLDSGDGVTHAVPIYEGFAMPHSIMRVDIAGRDV 190
           I++QAVL+L A+  +        TG V+DSGDGVTH +P+ EG+ +   I  + IAGRD+
Sbjct: 180 IAVQAVLALAASWTSRNVGERTLTGTVIDSGDGVTHVIPVAEGYVIGSCIKHIPIAGRDI 359

Query: 191 SRYLRLLLRKEGADFHTSAEFEVVRTIKERACYLSINPQKD-EALETEKVQYTLP-DGS- 247
           + +++ LLR+           E  + IKER  Y+  +  K+    +T+  ++    +G  
Sbjct: 360 TYFIQQLLREREVGIPPEQSLETAKAIKERFSYVCPDIAKEFSKYDTDPSKWMKKYEGRN 539

Query: 248 -------TLDVGPARFRAPELLFQPDLVG-DESEGLHEVLAFAIHKSDMDLRRTLFSNIV 299
                  ++DVG  RF  PE+ F P+    D +  + +V+   I    +D+RR L+ NIV
Sbjct: 540 TISKQLFSVDVGYERFLGPEIFFHPEFSNPDFTMPISDVVDDVIQNCPIDVRRGLYKNIV 719

Query: 300 LSGGSTLFKGFGDRLLSEVK----------------KLAPKDVKIKISAPQERLYSTWIG 343
           LSGGST+F+ FG ++  +VK                ++ PK +++++     + Y+ W G
Sbjct: 720 LSGGSTMFRDFGRKIQRDVKRVVDGRLKASEELSQGRIKPKPIEVQVITHHMQRYAVWFG 899

Query: 344 GSILASLDTFKKMWVSKKEYEEDG 367
           GS+LAS   F ++  +K +Y+E G
Sbjct: 900 GSMLASTPEFYQVCHTKADYDEHG 971
>32273
          Length = 265

 Score =  176 bits (446), Expect = 1e-44,   Method: Compositional matrix adjust.
 Identities = 78/88 (88%), Positives = 86/88 (97%)
 Frame = -2

Query: 68  LLTIRYPMEHGVVRDWNDMERIWQYVYSKDQLQTFSEEHPVLLTEAPLNPSKNREKAAEV 127
           L++IRYPMEHG+V+DWNDMERIWQY+YSKDQLQTFSEEHPVLLTEAPLNP +NREKAAE+
Sbjct: 264 LMSIRYPMEHGIVKDWNDMERIWQYIYSKDQLQTFSEEHPVLLTEAPLNPRRNREKAAEI 85

Query: 128 FFETFNVPALFISMQAVLSLYATGRTTG 155
           FF+TFNVPALFISMQAVLSLYATGR TG
Sbjct: 84  FFDTFNVPALFISMQAVLSLYATGRITG 1
>01436
          Length = 2563

 Score =  129 bits (325), Expect = 2e-30,   Method: Compositional matrix adjust.
 Identities = 75/200 (37%), Positives = 112/200 (56%), Gaps = 16/200 (8%)
 Frame = +3

Query: 190 VSRYLRLLLRKEGADFHTSAEFEVVRTIKERACYLSINPQKDEALETEKV----QYTLPD 245
           ++RYL  LL   G  F+ SA+FE VR +KE+ CY + + ++++ L  E       Y LPD
Sbjct: 3   ITRYLIKLLLLRGYAFNHSADFETVRMLKEKLCYTAYDVEQEQKLALETTVLVEPYILPD 182

Query: 246 GSTLDVGPARFRAPELLFQPDLVGDESEGLHEVLAFAIHKSDMDLRRTLFSNIVLSGGST 305
           G  + VG  RF APE LFQP L+  +  G+ E+L   I  +DMD+R   + +IVLSGGST
Sbjct: 183 GRVIKVGGERFEAPEALFQPHLINVDGVGVAELLFNTIQAADMDIRPDFYKHIVLSGGST 362

Query: 306 LFKGFGDRLLSEVKKLAPKDV-----------KIKISAPQERLYSTWIGGSILASLDTFK 354
           ++ G   RL  E+K+L  + V           KI+I  P  R +  ++GGS+ A +   K
Sbjct: 363 MYPGLPSRLEREIKQLYLERVLXGDTSRLSKFKIRIEDPPRRKHMVFLGGSVXADIMKDK 542

Query: 355 -KMWVSKKEYEEDGSRAIHR 373
              W+ + EYEE G + + +
Sbjct: 543 DDFWMMRSEYEEMGVKVLDK 602
>19721
          Length = 757

 Score = 91.7 bits (226), Expect(2) = 3e-30,   Method: Compositional matrix adjust.
 Identities = 55/121 (45%), Positives = 78/121 (64%), Gaps = 8/121 (6%)
 Frame = +2

Query: 79  VVRDWNDMERIWQYVYSKDQLQTFSEEHPVLLTEAPLNPSKNREKAAEVFFETFNVPALF 138
           VV DW+  ER  +    K  L+   E+H  LLTE PLN  +NRE  AE+ FETFN+P L+
Sbjct: 2   VVEDWDLHERFMEQAIFK-YLRAEPEDHYFLLTEPPLNTPENREFTAEIMFETFNIPGLY 178

Query: 139 ISMQAVLSLYATGRT--------TGVVLDSGDGVTHAVPIYEGFAMPHSIMRVDIAGRDV 190
           I++QAVL+L A+  +        TG V+DSGDGVTH +P+ +G+ +  +I  + IAGRD+
Sbjct: 179 IAVQAVLALAASWTSRPPNERTLTGTVIDSGDGVTHVIPVVDGYVIGSAIKHIPIAGRDI 358

Query: 191 S 191
           +
Sbjct: 359 T 361

 Score = 58.2 bits (139), Expect(2) = 3e-30,   Method: Compositional matrix adjust.
 Identities = 39/109 (35%), Positives = 59/109 (54%), Gaps = 12/109 (11%)
 Frame = +3

Query: 212 EVVRTIKERACYLSINPQKDEA---------LETEKVQYT--LPDGSTLDVGPARFRAPE 260
           E  + IKER  Y+  +  K+ A         ++  K+  +   PD S  DVG  +F  PE
Sbjct: 420 EAAKQIKERYSYVCPDIAKEFAKYDSDPEKWIKAHKMSGSSKYPDFS-FDVGYEKFLGPE 596

Query: 261 LLFQPDLV-GDESEGLHEVLAFAIHKSDMDLRRTLFSNIVLSGGSTLFK 308
           + F+P+ V GD    + +V+   I    +D RR L++NIVLSGGS++FK
Sbjct: 597 VFFRPEFVNGDFQASISDVVDTVIQSCPIDSRRPLYNNIVLSGGSSMFK 743
>36954
          Length = 892

 Score =  119 bits (297), Expect = 3e-27,   Method: Compositional matrix adjust.
 Identities = 63/199 (31%), Positives = 111/199 (55%), Gaps = 9/199 (4%)
 Frame = -1

Query: 12  VVIDNGSGVIKAGFAGDQIPKYCFPNYVGRPKHMRVMAGALEGDLFIGPKAEEHRGLLTI 71
           +V D GS   +AG+AG+  PK   P +VG  + +        GD    P+ +     + +
Sbjct: 802 LVFDIGSYSFRAGYAGEDTPKAEIPTHVGVMEDIETTMDTDGGDAPPQPEKKYLIDTVYM 623

Query: 72  RYP---------MEHGVVRDWNDMERIWQYVYSKDQLQTFSEEHPVLLTEAPLNPSKNRE 122
           ++P         ++ G+V DW+  E++  Y Y++  +++ S  HP+L++E   N    RE
Sbjct: 622 KHPRKGMHLNSFLKDGMVEDWDMFEKVIDYAYNR-SIKSESCLHPLLMSEPAWNTKAKRE 446

Query: 123 KAAEVFFETFNVPALFISMQAVLSLYATGRTTGVVLDSGDGVTHAVPIYEGFAMPHSIMR 182
           K  E+ FE +N+PA F+   +VLS +A GR+T ++LDSG   T AVP+Y+G+ +   I++
Sbjct: 445 KLTEIMFEKYNIPAFFLRKNSVLSAFANGRSTALILDSGATHTSAVPVYDGYVLTQGIVK 266

Query: 183 VDIAGRDVSRYLRLLLRKE 201
             +AG  ++R   LL+ ++
Sbjct: 265 SPLAGDFIARECGLLMEEQ 209
>11487
          Length = 771

 Score = 67.0 bits (162), Expect(3) = 3e-20,   Method: Compositional matrix adjust.
 Identities = 28/42 (66%), Positives = 34/42 (80%)
 Frame = -2

Query: 335 ERLYSTWIGGSILASLDTFKKMWVSKKEYEEDGSRAIHRKTF 376
           ER YS WIGGSILASL TF++MW+SK+EY+E G   +HRK F
Sbjct: 599 ERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF 474

 Score = 45.4 bits (106), Expect(3) = 3e-20,   Method: Compositional matrix adjust.
 Identities = 18/36 (50%), Positives = 27/36 (75%)
 Frame = -1

Query: 282 AIHKSDMDLRRTLFSNIVLSGGSTLFKGFGDRLLSE 317
           +I K D+D+R+ L++N VLSGG+T+F G  DR+  E
Sbjct: 756 SIMKCDVDIRKDLYANTVLSGGTTMFPGIADRMQKE 649

 Score = 23.5 bits (49), Expect(3) = 3e-20,   Method: Compositional matrix adjust.
 Identities = 10/18 (55%), Positives = 12/18 (66%)
 Frame = -3

Query: 318 VKKLAPKDVKIKISAPQE 335
           +  LAP  +KIKI APQ 
Sbjct: 649 ITALAPPTMKIKIIAPQN 596
>18926
          Length = 478

 Score = 95.1 bits (235), Expect = 5e-20,   Method: Compositional matrix adjust.
 Identities = 42/105 (40%), Positives = 70/105 (66%), Gaps = 3/105 (2%)
 Frame = +1

Query: 274 GLHEVLAFAIHKSDMDLRRTLFSNIVLSGGSTLFKGFGDRLLSEVKKLAPKDVKIKI--- 330
           G+  V+  ++   D+D+R +L+  ++  GG++L +GF +RL  ++    P  +++KI   
Sbjct: 97  GVGHVVTTSVGMCDIDIRPSLYGGVIAVGGNSLIQGFTERLNRDLSNKTPPSMRLKIIAA 276

Query: 331 SAPQERLYSTWIGGSILASLDTFKKMWVSKKEYEEDGSRAIHRKT 375
           ++  ER +S+WIGGSILASL +F++MWVSK+EYEE G   + RK 
Sbjct: 277 ASTAERRFSSWIGGSILASLGSFQQMWVSKQEYEEGGKSCVERKC 411
>13361
          Length = 1217

 Score = 89.7 bits (221), Expect = 2e-18,   Method: Compositional matrix adjust.
 Identities = 49/137 (35%), Positives = 74/137 (54%), Gaps = 17/137 (12%)
 Frame = +3

Query: 248 TLDVGPARFRAPELLFQPDLVG-DESEGLHEVLAFAIHKSDMDLRRTLFSNIVLSGGSTL 306
            +DVG  RF  PE+ F P+    D +  L E++   I    +D+RR L++NIVLSGGST+
Sbjct: 150 NVDVGYERFLGPEIFFHPEFSNPDFTIPLSEIVDNVIQNCPIDVRRHLYNNIVLSGGSTM 329

Query: 307 FKGFGDRLLSEVK----------------KLAPKDVKIKISAPQERLYSTWIGGSILASL 350
           FK FG RL  ++K                ++ PK + +++     + Y+ W GGS+LAS 
Sbjct: 330 FKDFGRRLQRDIKRSVDTRLRISENLSEGRIKPKPIDVQVITHHMQRYAVWFGGSMLAST 509

Query: 351 DTFKKMWVSKKEYEEDG 367
             F ++  +K  YEE G
Sbjct: 510 PEFYQVCHTKAAYEEYG 560
>26639
          Length = 435

 Score = 30.4 bits (67), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 16/37 (43%), Positives = 21/37 (56%)
 Frame = +2

Query: 44 HMRVMAGALEGDLFIGPKAEEHRGLLTIRYPMEHGVV 80
          H +V+AGALEGD+          G   IR P++HG V
Sbjct: 71 HGKVLAGALEGDV----------GSTNIRXPVQHGHV 151
>14855
          Length = 1907

 Score = 27.7 bits (60), Expect = 7.0,   Method: Compositional matrix adjust.
 Identities = 12/29 (41%), Positives = 18/29 (62%)
 Frame = +1

Query: 204  DFHTSAEFEVVRTIKERACYLSINPQKDE 232
            +FH S EFE ++ I  + CY S + Q +E
Sbjct: 1015 NFHVSKEFE*MKVINIKCCYESDSEQMEE 1101
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|225543319|ref|NP_033529.3| valosin containing protein
[Mus musculus]
         (806 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

38672                                                                 384   e-124
03022                                                                 250   9e-79
06766                                                                 202   6e-52
07243                                                                 201   8e-52
01642                                                                 199   4e-51
02582                                                                 197   1e-50
23766                                                                 168   2e-48
19129                                                                 170   2e-42
07247                                                                 144   2e-38
12235                                                                 139   6e-33
00810                                                                 125   8e-29
20270                                                                 114   1e-25
02191                                                                 100   4e-21
25671                                                                  82   9e-16
26408                                                                  79   8e-15
17843                                                                  61   2e-09
25936                                                                  59   6e-09
02194                                                                  54   3e-07
29846                                                                  46   7e-05
05247                                                                  34   8e-04
08000                                                                  39   0.006
01279                                                                  39   0.008
15498                                                                  36   0.067
19561                                                                  32   1.1  
27434                                                                  30   3.0  
01793                                                                  30   3.4  
30736                                                                  30   5.2  
>38672
          Length = 730

 Score =  384 bits (987), Expect(2) = e-124,   Method: Compositional matrix adjust.
 Identities = 183/206 (88%), Positives = 199/206 (96%)
 Frame = -3

Query: 311 PKREKTHGEVERRIVSQLLTLMDGLKQRAHVIVMAATNRPNSIDPALRRFGRFDREVDIG 370
           PK  +THGEVERRIVSQLLTLMDGLKQR+HVIVMAATNRPNS+D ALRRFGRFDREVDIG
Sbjct: 620 PKERETHGEVERRIVSQLLTLMDGLKQRSHVIVMAATNRPNSVDAALRRFGRFDREVDIG 441

Query: 371 IPDATGRLEILQIHTKNMKLADDVDLEQVANETHGHVGADLAALCSEAALQAIRKKMDLI 430
           IPDATGRLEIL+IHTKNMKLADDVDLEQVA+ETHGHVGAD+AALCSEAALQ IR+KMDLI
Sbjct: 440 IPDATGRLEILRIHTKNMKLADDVDLEQVASETHGHVGADVAALCSEAALQQIREKMDLI 261

Query: 431 DLEDETIDAEVMNSLAVTMDDFRWALSQSNPSALRETVVEVPQVTWEDIGGLEDVKRELQ 490
           DLED+TIDAEV++SLAVTMDDFRWAL +SNPSALRET VEVP V+WED+GGLE+VK+ELQ
Sbjct: 260 DLEDDTIDAEVLDSLAVTMDDFRWALGKSNPSALRETCVEVPNVSWEDVGGLENVKKELQ 81

Query: 491 ELVQYPVEHPDKFLKFGMTPSKGVLF 516
           ELVQYPVEHP+KFLKFGMTPSKGVLF
Sbjct: 80  ELVQYPVEHPEKFLKFGMTPSKGVLF 3

 Score = 82.0 bits (201), Expect(2) = e-124,   Method: Compositional matrix adjust.
 Identities = 41/42 (97%), Positives = 42/42 (100%)
 Frame = -1

Query: 274 IMSKLAGESESNLRKAFEEAEKNAPAIIFIDELDAIAPKREK 315
           IMSKLAGESESNLRKAFEEAEKNAPAIIFIDELDAIAPKRE+
Sbjct: 730 IMSKLAGESESNLRKAFEEAEKNAPAIIFIDELDAIAPKRER 605

 Score = 85.9 bits (211), Expect(2) = 6e-23,   Method: Compositional matrix adjust.
 Identities = 39/97 (40%), Positives = 63/97 (64%)
 Frame = -3

Query: 599 RVINQILTEMDGMSTKKNVFIIGATNRPDIIDPAILRPGRLDQLIYIPLPDEKSRVAILK 658
           R+++Q+LT MDG+  + +V ++ ATNRP+ +D A+ R GR D+ + I +PD   R+ IL+
Sbjct: 584 RIVSQLLTLMDGLKQRSHVIVMAATNRPNSVDAALRRFGRFDREVDIGIPDATGRLEILR 405

Query: 659 ANLRKSPVAKDVDLEFLAKMTNGFSGADLTEICQRAC 695
            + +   +A DVDLE +A  T+G  GAD+  +C  A 
Sbjct: 404 IHTKNMKLADDVDLEQVASETHGHVGADVAALCSEAA 294

 Score = 40.8 bits (94), Expect(2) = 6e-23,   Method: Compositional matrix adjust.
 Identities = 16/36 (44%), Positives = 28/36 (77%)
 Frame = -1

Query: 547 LLTMWFGESEANVREIFDKARQAAPCVLFFDELDSI 582
           +++   GESE+N+R+ F++A + AP ++F DELD+I
Sbjct: 730 IMSKLAGESESNLRKAFEEAEKNAPAIIFIDELDAI 623

 Score = 40.4 bits (93), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 14/43 (32%), Positives = 26/43 (60%)
 Frame = -3

Query: 201 VGYDDIGGCRKQLAQIKEMVELPLRHPALFKAIGVKPPRGILL 243
           V ++D+GG      +++E+V+ P+ HP  F   G+ P +G+L 
Sbjct: 131 VSWEDVGGLENVKKELQELVQYPVEHPEKFLKFGMTPSKGVLF 3
>03022
          Length = 2255

 Score =  250 bits (638), Expect(2) = 9e-79,   Method: Compositional matrix adjust.
 Identities = 151/401 (37%), Positives = 222/401 (55%), Gaps = 25/401 (6%)
 Frame = +2

Query: 323  RIVSQLLTLMDGLKQRA-HVIVMAATNRPNSIDPALRRFGRFDREVDIGIPDATGRLEIL 381
            RIVS+L + +D L+++  +V+V+A T+R  ++   LR  GRF  E  +G+PD   R  +L
Sbjct: 899  RIVSELGSCIDELQEKPENVVVVATTSRIEAVHRDLRIPGRF-MEKALGMPDEGSREGLL 1075

Query: 382  QIHTKNMKLADDVDLEQVANETHGHVGADLAALCSEAALQAIRKKMDLIDLE-------- 433
            Q       L+  + L+ +A  T G V  DL AL   A   A R+  +L   E        
Sbjct: 1076 QRLCSRYTLSPHLKLKTLARLTPGFVAGDLRALVHGAFSTAFRRVRNLYRTESAESSTRR 1255

Query: 434  --------------DETIDAEVMNSLAVTMDDFRWALSQSNPSALRETVVEVPQVTWEDI 479
                          D     + + ++A+T +DF  AL ++ P+A RE    VP  TWED+
Sbjct: 1256 HPFPPLPPAHLTGKDIXPQEQDIAAVALTEEDFMGALKKAQPAAKREGFATVPTTTWEDV 1435

Query: 480  GGLEDVKRELQELVQYPVEHPDKFLKFGMTPSKGVLFYGPPGCGKTLLAKAIANECQANF 539
            G L +V+ +L++ +   +  P+    FG+  + G++  GPPGCGKTL+AKA+ANE   NF
Sbjct: 1436 GALSNVRAQLKDSILCRIHDPEVSSAFGLPTNSGIILVGPPGCGKTLVAKAMANEAGLNF 1615

Query: 540  ISIKGPELLTMWFGESEANVREIFDKARQAAPCVLFFDELDSIXXXXXXXXXXXXXXXDR 599
            I IKGPELL  + GESE N+RE FDKA+  APC++FFDE+D++                 
Sbjct: 1616 IYIKGPELLDKYVGESERNLREKFDKAQACAPCLIFFDEMDTLCSNRQNNDGSNVGKS-- 1789

Query: 600  VINQILTEMDGMSTKKNVFIIGATNRPDIIDPAILRPGRLDQLIYIPLPDEKSRVAILKA 659
            V NQ+L  MDG   +  V+++GATN  + +DPA+ RPGR D+ I+I LPD   R+ IL+A
Sbjct: 1790 VTNQLLALMDGCGERSQVYVMGATNIIENVDPALQRPGRFDRKIFIGLPDTDGRLDILRA 1969

Query: 660  NLRKSPVAK--DVDLEFLAKMTNGFSGADLTEICQRACKLA 698
              +     K    D++ LA+ T GFSGADL  +   A  +A
Sbjct: 1970 LTKGGSQRKLESCDMQQLAQDTEGFSGADLKHLVNEASTIA 2092

 Score = 63.2 bits (152), Expect(2) = 9e-79,   Method: Compositional matrix adjust.
 Identities = 37/128 (28%), Positives = 65/128 (50%), Gaps = 2/128 (1%)
 Frame = +1

Query: 193 DEEESLNEVGYDDIGGCRKQLAQIKEMVE--LPLRHPALFKAIGVKPPRGILLYGPPGTG 250
           D E S+     DD GG  K LA++    E  L   +     A   K  R  LLYGP G+G
Sbjct: 496 DGEPSIPTATLDDFGGSNKLLAELDSDFEEILYSDYCQYASACDQKACRRYLLYGPRGSG 675

Query: 251 KTLIARAVANETGAFFFLINGPEIMSKLAGESESNLRKAFEEAEKNAPAIIFIDELDAIA 310
           K  +A  +A +            ++S ++G+SE  +R  F++A   AP ++++++++ +A
Sbjct: 676 KRFLAECIAGQLKLPLLKPKINTLISGVSGDSEQRVRDLFDQAVSQAPCVLYLEDIECLA 855

Query: 311 PKREKTHG 318
           P+++   G
Sbjct: 856 PRQDTPXG 879

 Score =  201 bits (511), Expect = 1e-51,   Method: Compositional matrix adjust.
 Identities = 109/284 (38%), Positives = 167/284 (58%), Gaps = 3/284 (1%)
 Frame = +2

Query: 185  EGEPIKREDEEESLNEVGYDDIGGCRKQLAQIKEMVELPLRHPALFKAIGVKPPRGILLY 244
            + +P  + +   ++    ++D+G      AQ+K+ +   +  P +  A G+    GI+L 
Sbjct: 1370 KAQPAAKREGFATVPTTTWEDVGALSNVRAQLKDSILCRIHDPEVSSAFGLPTNSGIILV 1549

Query: 245  GPPGTGKTLIARAVANETGAFFFLINGPEIMSKLAGESESNLRKAFEEAEKNAPAIIFID 304
            GPPG GKTL+A+A+ANE G  F  I GPE++ K  GESE NLR+ F++A+  AP +IF D
Sbjct: 1550 GPPGCGKTLVAKAMANEAGLNFIYIKGPELLDKYVGESERNLREKFDKAQACAPCLIFFD 1729

Query: 305  ELDAIAPKREKTHGE-VERRIVSQLLTLMDGLKQRAHVIVMAATNRPNSIDPALRRFGRF 363
            E+D +   R+   G  V + + +QLL LMDG  +R+ V VM ATN   ++DPAL+R GRF
Sbjct: 1730 EMDTLCSNRQNNDGSNVGKSVTNQLLALMDGCGERSQVYVMGATNIIENVDPALQRPGRF 1909

Query: 364  DREVDIGIPDATGRLEILQIHTK--NMKLADDVDLEQVANETHGHVGADLAALCSEAALQ 421
            DR++ IG+PD  GRL+IL+  TK  + +  +  D++Q+A +T G  GADL  L +EA+  
Sbjct: 1910 DRKIFIGLPDTDGRLDILRALTKGGSQRKLESCDMQQLAQDTEGFSGADLKHLVNEASTI 2089

Query: 422  AIRKKMDLIDLEDETIDAEVMNSLAVTMDDFRWALSQSNPSALR 465
            A+++ M      D+    +      VT D F  AL    PS ++
Sbjct: 2090 ALKESM-----ADQAWREDSHREYVVTGDQFTRALQLVKPSVMK 2206

 Score = 57.4 bits (137), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 41/145 (28%), Positives = 67/145 (46%), Gaps = 9/145 (6%)
 Frame = +1

Query: 447 VTMDDFRWALSQSNPSALRETVVEVPQVTWEDIGG----LEDVKRELQELV-----QYPV 497
           +  DD    L    PS        +P  T +D GG    L ++  + +E++     QY  
Sbjct: 463 MKTDDLDMDLPDGEPS--------IPTATLDDFGGSNKLLAELDSDFEEILYSDYCQYAS 618

Query: 498 EHPDKFLKFGMTPSKGVLFYGPPGCGKTLLAKAIANECQANFISIKGPELLTMWFGESEA 557
               K         +  L YGP G GK  LA+ IA + +   +  K   L++   G+SE 
Sbjct: 619 ACDQK-------ACRRYLLYGPRGSGKRFLAECIAGQLKLPLLKPKINTLISGVSGDSEQ 777

Query: 558 NVREIFDKARQAAPCVLFFDELDSI 582
            VR++FD+A   APCVL+ ++++ +
Sbjct: 778 RVRDLFDQAVSQAPCVLYLEDIECL 852
>06766
          Length = 976

 Score =  202 bits (513), Expect = 6e-52,   Method: Compositional matrix adjust.
 Identities = 102/139 (73%), Positives = 114/139 (82%), Gaps = 2/139 (1%)
 Frame = +2

Query: 638 RLDQLIYIPLPDEKSRVAILKANLRKSPVAKDVDLEFLAKMTNGFSGADLTEICQRACKL 697
           RLDQLIYIPLPD+KSR AILKANLRKSP+AK+VDL ++AK+T GFSGADLTEICQRACKL
Sbjct: 2   RLDQLIYIPLPDDKSREAILKANLRKSPLAKEVDLTYIAKVTQGFSGADLTEICQRACKL 181

Query: 698 AXXXXXXXXXXXXXXXQTNP-SAMEVEEDDPVPEIRRDHFEEAMRFARRSVSDNDIRKYE 756
           A                 N  SAM+++E+DPVPEI R HFEEAM+FARRSVSDNDIRKYE
Sbjct: 182 AIRQAIEAEIRREKDRAENQNSAMDMDEEDPVPEITRAHFEEAMKFARRSVSDNDIRKYE 361

Query: 757 MFAQTLQQSRGFG-SFRFP 774
           MFAQTLQQSRGFG +FRFP
Sbjct: 362 MFAQTLQQSRGFGQNFRFP 418

 Score = 49.3 bits (116), Expect = 6e-06,   Method: Compositional matrix adjust.
 Identities = 33/90 (36%), Positives = 49/90 (54%)
 Frame = +2

Query: 362 RFDREVDIGIPDATGRLEILQIHTKNMKLADDVDLEQVANETHGHVGADLAALCSEAALQ 421
           R D+ + I +PD   R  IL+ + +   LA +VDL  +A  T G  GADL  +C  A   
Sbjct: 2   RLDQLIYIPLPDDKSREAILKANLRKSPLAKEVDLTYIAKVTQGFSGADLTEICQRACKL 181

Query: 422 AIRKKMDLIDLEDETIDAEVMNSLAVTMDD 451
           AIR+ ++  ++  E   AE  NS A+ MD+
Sbjct: 182 AIRQAIE-AEIRREKDRAENQNS-AMDMDE 265
>07243
          Length = 1112

 Score =  201 bits (512), Expect = 8e-52,   Method: Compositional matrix adjust.
 Identities = 104/275 (37%), Positives = 164/275 (59%)
 Frame = +1

Query: 424 RKKMDLIDLEDETIDAEVMNSLAVTMDDFRWALSQSNPSALRETVVEVPQVTWEDIGGLE 483
           R+++D   L+  T  A  M +L +     R+   + +P     +  +   VT+  IGGL 
Sbjct: 58  RRQLDKAKLKSGTRVALDMTTLTI----MRYLPREVDPLVYNMSHEDPGDVTYSAIGGLT 225

Query: 484 DVKRELQELVQYPVEHPDKFLKFGMTPSKGVLFYGPPGCGKTLLAKAIANECQANFISIK 543
           +  REL+E+++ P+ +P+ FL+ G+TP KG L YGPPG GKTLLA+A+A++  ANF+ + 
Sbjct: 226 EQIRELREVIELPLLNPELFLRVGITPPKGCLLYGPPGTGKTLLARAVASQLDANFLKVV 405

Query: 544 GPELLTMWFGESEANVREIFDKARQAAPCVLFFDELDSIXXXXXXXXXXXXXXXDRVINQ 603
              ++  + GES   +RE+F+ AR   PC++F DE+D+I                R + +
Sbjct: 406 SSAIVDKYIGESARLIREMFNYARDHQPCIIFMDEIDAIGGRRFSEGTSADREIQRTLME 585

Query: 604 ILTEMDGMSTKKNVFIIGATNRPDIIDPAILRPGRLDQLIYIPLPDEKSRVAILKANLRK 663
           +L +MDG  +   V +I ATNRPD +DPA+LRPGRLD+ I IPLP+E++R+ ILK +   
Sbjct: 586 LLNQMDGFDSLGQVKMIMATNRPDTLDPALLRPGRLDRKIEIPLPNEQARLEILKIHALI 765

Query: 664 SPVAKDVDLEFLAKMTNGFSGADLTEICQRACKLA 698
                ++D E + K+++ F+GADL  +C  A   A
Sbjct: 766 IAKHGEIDYEAIVKLSDNFNGADLRNVCTEAGLFA 870

 Score =  196 bits (497), Expect = 4e-50,   Method: Compositional matrix adjust.
 Identities = 106/253 (41%), Positives = 156/253 (61%), Gaps = 3/253 (1%)
 Frame = +1

Query: 185 EGEPIKREDEEESLNEVGYDDIGGCRKQLAQIKEMVELPLRHPALFKAIGVKPPRGILLY 244
           E +P+      E   +V Y  IGG  +Q+ +++E++ELPL +P LF  +G+ PP+G LLY
Sbjct: 148 EVDPLVYNMSHEDPGDVTYSAIGGLTEQIRELREVIELPLLNPELFLRVGITPPKGCLLY 327

Query: 245 GPPGTGKTLIARAVANETGAFFFLINGPEIMSKLAGESESNLRKAFEEAEKNAPAIIFID 304
           GPPGTGKTL+ARAVA++  A F  +    I+ K  GES   +R+ F  A  + P IIF+D
Sbjct: 328 GPPGTGKTLLARAVASQLDANFLKVVSSAIVDKYIGESARLIREMFNYARDHQPCIIFMD 507

Query: 305 ELDAIAPKR--EKTHGEVE-RRIVSQLLTLMDGLKQRAHVIVMAATNRPNSIDPALRRFG 361
           E+DAI  +R  E T  + E +R + +LL  MDG      V ++ ATNRP+++DPAL R G
Sbjct: 508 EIDAIGGRRFSEGTSADREIQRTLMELLNQMDGFDSLGQVKMIMATNRPDTLDPALLRPG 687

Query: 362 RFDREVDIGIPDATGRLEILQIHTKNMKLADDVDLEQVANETHGHVGADLAALCSEAALQ 421
           R DR+++I +P+   RLEIL+IH   +    ++D E +   +    GADL  +C+EA L 
Sbjct: 688 RLDRKIEIPLPNEQARLEILKIHALIIAKHGEIDYEAIVKLSDNFNGADLRNVCTEAGLF 867

Query: 422 AIRKKMDLIDLED 434
           AIR + + +  ED
Sbjct: 868 AIRAEREYVIQED 906
>01642
          Length = 1406

 Score =  199 bits (506), Expect = 4e-51,   Method: Compositional matrix adjust.
 Identities = 104/226 (46%), Positives = 143/226 (63%), Gaps = 3/226 (1%)
 Frame = -1

Query: 203 YDDIGGCRKQLAQIKEMVELPLRHPALFKAIGVKPPRGILLYGPPGTGKTLIARAVANET 262
           Y DIGG   Q  +++E VELPL H  L+K IG+ PPRG+L+YGPPG GKT++A+AVA+ T
Sbjct: 998 YSDIGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAKAVAHHT 819

Query: 263 GAFFFLINGPEIMSKLAGESESNLRKAFEEAEKNAPAIIFIDELDAIAPKREKTHGEVER 322
            A F  + G E + K  GE    +R  F  A++NAPAIIFIDE+DAIA KR       +R
Sbjct: 818 TAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRFDAQTGADR 639

Query: 323 ---RIVSQLLTLMDGLKQRAHVIVMAATNRPNSIDPALRRFGRFDREVDIGIPDATGRLE 379
              RI+ +LL  MDG  Q  +V V+ ATNR +++DPAL R GR DR+++  +PD   +  
Sbjct: 638 EVQRILLELLNQMDGFDQTVNVKVIMATNRADTLDPALLRPGRLDRKIEFPLPDRRQKRL 459

Query: 380 ILQIHTKNMKLADDVDLEQVANETHGHVGADLAALCSEAALQAIRK 425
           I    T  M ++++VDLE          GAD+ A+C EA +QA+R+
Sbjct: 458 IFSTITGKMNISEEVDLEDYVARPDKISGADINAICQEAGMQAVRE 321

 Score =  185 bits (469), Expect = 7e-47,   Method: Compositional matrix adjust.
 Identities = 116/368 (31%), Positives = 171/368 (46%), Gaps = 28/368 (7%)
 Frame = -1

Query: 355  PALRRFGRFDREVD-----IGIPDATGRLEIL----------------QIHTKNMKLADD 393
            P+  R GRF RE+       G+P  +GR+                   Q HT+       
Sbjct: 1397 PSQXRRGRFVREIQEASETAGVPGGSGRVHQG*AEEPEEGVPARPGGGQAHTERASRHRA 1218

Query: 394  VDLEQVANETHGHVGADLAALCSEAALQAIRKKMDLIDLEDETIDAEVMNSLAVTMDDFR 453
            V   +     H  +   +  LC+       R    +I                       
Sbjct: 1217 VSGGRRPKHRHCRLNYRVQLLCAYFVYNRPRASQAVIQCCSPQTQQ-------------- 1080

Query: 454  WALSQSNPSALRETVVE-------VPQVTWEDIGGLEDVKRELQELVQYPVEHPDKFLKF 506
               S   PS  R T V         P   + DIGG++  K+E++E V+ P+ H + + + 
Sbjct: 1079 --CSCGRPSPQRLTAVSQCFKLMRSPT*XYSDIGGMDIQKQEVREAVELPLTHFELYKQI 906

Query: 507  GMTPSKGVLFYGPPGCGKTLLAKAIANECQANFISIKGPELLTMWFGESEANVREIFDKA 566
            G+ P +GVL YGPPGCGKT+LAKA+A+   A FI + G E +  + GE    VR++F  A
Sbjct: 905  GIDPPRGVLMYGPPGCGKTMLAKAVAHHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLA 726

Query: 567  RQAAPCVLFFDELDSIXXXXXXXXXXXXXXXDRVINQILTEMDGMSTKKNVFIIGATNRP 626
            ++ AP ++F DE+D+I                R++ ++L +MDG     NV +I ATNR 
Sbjct: 725  KENAPAIIFIDEIDAIATKRFDAQTGADREVQRILLELLNQMDGFDQTVNVKVIMATNRA 546

Query: 627  DIIDPAILRPGRLDQLIYIPLPDEKSRVAILKANLRKSPVAKDVDLEFLAKMTNGFSGAD 686
            D +DPA+LRPGRLD+ I  PLPD + +  I      K  ++++VDLE      +  SGAD
Sbjct: 545  DTLDPALLRPGRLDRKIEFPLPDRRQKRLIFSTITGKMNISEEVDLEDYVARPDKISGAD 366

Query: 687  LTEICQRA 694
            +  ICQ A
Sbjct: 365  INAICQEA 342
>02582
          Length = 1101

 Score =  197 bits (501), Expect = 1e-50,   Method: Compositional matrix adjust.
 Identities = 115/349 (32%), Positives = 179/349 (51%), Gaps = 34/349 (9%)
 Frame = +3

Query: 446 AVTMDDFRWALSQSNPSALR--ETVVEVPQVTWEDIGGLEDVKRELQELVQYPVEHPDKF 503
            +T  D   AL    PS  R  + +V+   V W DIGGL+ VK ++++ V++P+ +PD F
Sbjct: 42  GITRADMEAALLTFKPSMQRGVDCIVDARSVPWTDIGGLDLVKLQIRQAVEWPLLYPDTF 221

Query: 504 LKFGMTPSKGVLFYGPPGCGKTLLAKAIANECQANFISIKGPELLTMWFGESEANVREIF 563
              G+  +KGVL YGPPGCGKT LA+A A  C   F+S+   +L + + G++E  + E F
Sbjct: 222 QALGLPLTKGVLLYGPPGCGKTTLAQAAATACHVTFLSLSCAQLYSPYVGDAEKKISETF 401

Query: 564 DKARQAAPCVLFFDELDSIXXXXXXXXXXXXXXXDRVINQILTEMDGMSTK--------- 614
            KAR  AP +LF DE+D+I               +RV++ +L EMDG+  +         
Sbjct: 402 QKARALAPSILFLDEMDAI-VGKRSDSSLGSGVSERVLSALLNEMDGIGVRLDDKSDSRE 578

Query: 615 -----------------------KNVFIIGATNRPDIIDPAILRPGRLDQLIYIPLPDEK 651
                                  ++V ++ ATNRPD++DPA+LRPGR+D+LIY+P PD +
Sbjct: 579 MEIEGSSDHTPQVRQHAVKEAHDRHVLVVAATNRPDMLDPALLRPGRMDRLIYVPPPDVQ 758

Query: 652 SRVAILKANLRKSPVAKDVDLEFLAKMTNGFSGADLTEICQRACKLAXXXXXXXXXXXXX 711
            R+     + RK P+ KDVD++ LA +T G++GAD+  +C     LA             
Sbjct: 759 GRLQSFTIHTRKMPLGKDVDVKQLADLTAGYTGADIKTLCNEVGLLA------------- 899

Query: 712 XXQTNPSAMEVEEDDPVPEIRRDHFEEAMRFARRSVSDNDIRKYEMFAQ 760
                     ++E      + +DHF  A++  + S+S +      M+ Q
Sbjct: 900 ----------LKESMSAECVNQDHFLNAIKTRKPSLSADSSEVETMYKQ 1016

 Score =  171 bits (433), Expect = 9e-43,   Method: Compositional matrix adjust.
 Identities = 108/297 (36%), Positives = 159/297 (53%), Gaps = 34/297 (11%)
 Frame = +3

Query: 200 EVGYDDIGGCRKQLAQIKEMVELPLRHPALFKAIGVKPPRGILLYGPPGTGKTLIARAVA 259
            V + DIGG      QI++ VE PL +P  F+A+G+   +G+LLYGPPG GKT +A+A A
Sbjct: 129 SVPWTDIGGLDLVKLQIRQAVEWPLLYPDTFQALGLPLTKGVLLYGPPGCGKTTLAQAAA 308

Query: 260 NETGAFFFLINGPEIMSKLAGESESNLRKAFEEAEKNAPAIIFIDELDAIAPKREKTH-- 317
                 F  ++  ++ S   G++E  + + F++A   AP+I+F+DE+DAI  KR  +   
Sbjct: 309 TACHVTFLSLSCAQLYSPYVGDAEKKISETFQKARALAPSILFLDEMDAIVGKRSDSSLG 488

Query: 318 GEVERRIVSQLLTLMDGL-------------------------KQRA-------HVIVMA 345
             V  R++S LL  MDG+                         +Q A       HV+V+A
Sbjct: 489 SGVSERVLSALLNEMDGIGVRLDDKSDSREMEIEGSSDHTPQVRQHAVKEAHDRHVLVVA 668

Query: 346 ATNRPNSIDPALRRFGRFDREVDIGIPDATGRLEILQIHTKNMKLADDVDLEQVANETHG 405
           ATNRP+ +DPAL R GR DR + +  PD  GRL+   IHT+ M L  DVD++Q+A+ T G
Sbjct: 669 ATNRPDMLDPALLRPGRMDRLIYVPPPDVQGRLQSFTIHTRKMPLGKDVDVKQLADLTAG 848

Query: 406 HVGADLAALCSEAALQAIRKKMDLIDLEDETIDAEVMNSLAVTMDDFRWALSQSNPS 462
           + GAD+  LC+E  L A++          E++ AE +N      D F  A+    PS
Sbjct: 849 YTGADIKTLCNEVGLLALK----------ESMSAECVNQ-----DHFLNAIKTRKPS 974
>23766
          Length = 1463

 Score =  168 bits (425), Expect(2) = 2e-48,   Method: Compositional matrix adjust.
 Identities = 85/196 (43%), Positives = 127/196 (64%), Gaps = 3/196 (1%)
 Frame = +1

Query: 234 GVKPPRGILLYGPPGTGKTLIARAVANETGAFFFLINGPEIMSKLAGESESNLRKAFEEA 293
           G + P+G++LYGPPGTGKTL+A+AVAN+T A F  + G E++ K  G+    +R+ F  A
Sbjct: 142 GNQAPKGVILYGPPGTGKTLLAKAVANQTSATFLRVVGSELIQKYLGDGPKLVRELFRVA 321

Query: 294 EKNAPAIIFIDELDAIAPKREKTHGEVER---RIVSQLLTLMDGLKQRAHVIVMAATNRP 350
           E++AP+I+FIDE+DA+  KR +++   ER   R + +LL  +DG   R  V V+ ATNR 
Sbjct: 322 EEHAPSIVFIDEIDAVGTKRYESNSGGEREIQRTMLELLNQLDGFDSRGDVKVIMATNRI 501

Query: 351 NSIDPALRRFGRFDREVDIGIPDATGRLEILQIHTKNMKLADDVDLEQVANETHGHVGAD 410
            ++DPAL R GR DR+++  +PD   +  I  IHT  M LA DV+++          GAD
Sbjct: 502 ETLDPALIRPGRIDRKIEFPLPDEKTKRRIFTIHTSRMTLAGDVNIDDYVMSKDDLSGAD 681

Query: 411 LAALCSEAALQAIRKK 426
           + A+C+EA L A+R++
Sbjct: 682 IKAICTEAGLLALRER 729

 Score = 44.3 bits (103), Expect(2) = 2e-48,   Method: Composition-based stats.
 Identities = 18/34 (52%), Positives = 24/34 (70%)
 Frame = +2

Query: 203 YDDIGGCRKQLAQIKEMVELPLRHPALFKAIGVK 236
           Y DIGG   Q+ +IKE VELPL HP  ++ +G+K
Sbjct: 50  YADIGGLDTQIQEIKESVELPLTHPEYYEEMGIK 151

 Score =  151 bits (382), Expect(2) = 3e-42,   Method: Compositional matrix adjust.
 Identities = 74/192 (38%), Positives = 114/192 (59%)
 Frame = +1

Query: 507 GMTPSKGVLFYGPPGCGKTLLAKAIANECQANFISIKGPELLTMWFGESEANVREIFDKA 566
           G    KGV+ YGPPG GKTLLAKA+AN+  A F+ + G EL+  + G+    VRE+F  A
Sbjct: 142 GNQAPKGVILYGPPGTGKTLLAKAVANQTSATFLRVVGSELIQKYLGDGPKLVRELFRVA 321

Query: 567 RQAAPCVLFFDELDSIXXXXXXXXXXXXXXXDRVINQILTEMDGMSTKKNVFIIGATNRP 626
            + AP ++F DE+D++                R + ++L ++DG  ++ +V +I ATNR 
Sbjct: 322 EEHAPSIVFIDEIDAVGTKRYESNSGGEREIQRTMLELLNQLDGFDSRGDVKVIMATNRI 501

Query: 627 DIIDPAILRPGRLDQLIYIPLPDEKSRVAILKANLRKSPVAKDVDLEFLAKMTNGFSGAD 686
           + +DPA++RPGR+D+ I  PLPDEK++  I   +  +  +A DV+++      +  SGAD
Sbjct: 502 ETLDPALIRPGRIDRKIEFPLPDEKTKRRIFTIHTSRMTLAGDVNIDDYVMSKDDLSGAD 681

Query: 687 LTEICQRACKLA 698
           +  IC  A  LA
Sbjct: 682 IKAICTEAGLLA 717

 Score = 39.7 bits (91), Expect(2) = 3e-42,   Method: Composition-based stats.
 Identities = 16/43 (37%), Positives = 28/43 (65%)
 Frame = +2

Query: 470 EVPQVTWEDIGGLEDVKRELQELVQYPVEHPDKFLKFGMTPSK 512
           + PQ T+ DIGGL+   +E++E V+ P+ HP+ + + G+   K
Sbjct: 32  KAPQETYADIGGLDTQIQEIKESVELPLTHPEYYEEMGIKHQK 160
>19129
          Length = 1020

 Score =  170 bits (430), Expect = 2e-42,   Method: Compositional matrix adjust.
 Identities = 94/266 (35%), Positives = 151/266 (56%), Gaps = 9/266 (3%)
 Frame = +1

Query: 398 QVANETHGHVGADLAALCSEAALQAIRKKMDLIDLEDETIDAEVMNSLA----VTMDDFR 453
           Q+  E   +VG  +  +  +  L  +  +   +   D+ ID   MNS+     V + +  
Sbjct: 232 QLLQEQGSYVGEVVKPMDKKKVLVKVHPEGKFVVDIDKNID---MNSVTPNCRVALRNDS 402

Query: 454 WALSQSNPSALRETVV-----EVPQVTWEDIGGLEDVKRELQELVQYPVEHPDKFLKFGM 508
           + L +  P+ +   V      +VP  T+E +GGL+   +E++E+++ PV+HP+ F   G+
Sbjct: 403 YVLHKILPNKVDPLVSLMMVEKVPDSTYEMVGGLDKQIKEIKEVIELPVKHPELFEALGI 582

Query: 509 TPSKGVLFYGPPGCGKTLLAKAIANECQANFISIKGPELLTMWFGESEANVREIFDKARQ 568
              KGVL YGPPG GKTLLA+A+A+  +  FI + G EL+  + GE    VRE+F  AR+
Sbjct: 583 AQPKGVLLYGPPGTGKTLLARAVAHHTECTFIRVSGSELVQKFIGEGSRMVRELFVMARE 762

Query: 569 AAPCVLFFDELDSIXXXXXXXXXXXXXXXDRVINQILTEMDGMSTKKNVFIIGATNRPDI 628
            AP ++F DE+DSI                R + ++L ++DG   K+N+ +I ATNR DI
Sbjct: 763 HAPSIIFMDEIDSIGSSRLEGGSGGDSEVQRTMLELLNQLDGFEPKQNIKVIMATNRIDI 942

Query: 629 IDPAILRPGRLDQLIYIPLPDEKSRV 654
           +D A+LRPGR+D+ I  P P+E++R+
Sbjct: 943 LDSALLRPGRIDRKIEFPPPNEEARL 1020

 Score =  159 bits (402), Expect = 4e-39,   Method: Compositional matrix adjust.
 Identities = 81/180 (45%), Positives = 124/180 (68%), Gaps = 4/180 (2%)
 Frame = +1

Query: 203 YDDIGGCRKQLAQIKEMVELPLRHPALFKAIGVKPPRGILLYGPPGTGKTLIARAVANET 262
           Y+ +GG  KQ+ +IKE++ELP++HP LF+A+G+  P+G+LLYGPPGTGKTL+ARAVA+ T
Sbjct: 484 YEMVGGLDKQIKEIKEVIELPVKHPELFEALGIAQPKGVLLYGPPGTGKTLLARAVAHHT 663

Query: 263 GAFFFLINGPEIMSKLAGESESNLRKAFEEAEKNAPAIIFIDELDAIAPKR-EKTHG--- 318
              F  ++G E++ K  GE    +R+ F  A ++AP+IIF+DE+D+I   R E   G   
Sbjct: 664 ECTFIRVSGSELVQKFIGEGSRMVRELFVMAREHAPSIIFMDEIDSIGSSRLEGGSGGDS 843

Query: 319 EVERRIVSQLLTLMDGLKQRAHVIVMAATNRPNSIDPALRRFGRFDREVDIGIPDATGRL 378
           EV+R ++ +LL  +DG + + ++ V+ ATNR + +D AL R GR DR+++   P+   RL
Sbjct: 844 EVQRTML-ELLNQLDGFEPKQNIKVIMATNRIDILDSALLRPGRIDRKIEFPPPNEEARL 1020
>07247
          Length = 1753

 Score =  140 bits (352), Expect(2) = 2e-38,   Method: Compositional matrix adjust.
 Identities = 80/191 (41%), Positives = 115/191 (60%), Gaps = 3/191 (1%)
 Frame = -2

Query: 247  PGTGKTLIARAVANETGAFFFLINGPEIMSKLAGESESNLRKAFEEAEKNAPAIIFIDEL 306
            PGTGKTL+ARAVA++    F  +    I+ K  GES   +R+ F  A  + P IIF+DE+
Sbjct: 1407 PGTGKTLLARAVASQLDCNFLKVVSSAIVDKYIGESARLIREMFAFARDHEPCIIFMDEI 1228

Query: 307  DAIAPKR--EKTHGEVE-RRIVSQLLTLMDGLKQRAHVIVMAATNRPNSIDPALRRFGRF 363
            DAI  +R  E T  + E +R + +LL  MDG      V ++ ATNRP+++DPAL R GR 
Sbjct: 1227 DAIGGRRFSEGTSADREIQRTLMELLNQMDGFDALGQVKMIMATNRPDTLDPALLRPGRL 1048

Query: 364  DREVDIGIPDATGRLEILQIHTKNMKLADDVDLEQVANETHGHVGADLAALCSEAALQAI 423
            DR+++I +P+   RLEIL+IH   +    ++D E V   +    GADL  +C+EA + AI
Sbjct: 1047 DRKIEISLPNEQARLEILKIHANPIAKHGEIDWEAVVKLSEDFNGADLRNVCTEAGMFAI 868

Query: 424  RKKMDLIDLED 434
            R + D +  ED
Sbjct: 867  RAERDYVIEED 835

 Score = 38.5 bits (88), Expect(2) = 2e-38,   Method: Compositional matrix adjust.
 Identities = 15/49 (30%), Positives = 32/49 (65%)
 Frame = -1

Query: 187  EPIKREDEEESLNEVGYDDIGGCRKQLAQIKEMVELPLRHPALFKAIGV 235
            +P+      E   ++ ++ IGG  +Q+ +++E++ELPL +P LF+ +G+
Sbjct: 1585 DPLVYNMSVEDPGDITFNQIGGLGEQVRELREVIELPLLNPELFQRVGI 1439

 Score =  144 bits (362), Expect = 2e-34,   Method: Compositional matrix adjust.
 Identities = 77/201 (38%), Positives = 116/201 (57%), Gaps = 11/201 (5%)
 Frame = -2

Query: 509  TPSKGVLFYGP---------PGCGKTLLAKAIANECQANFISIKGPELLTMWFGESEANV 559
            TPS   ++  P         PG GKTLLA+A+A++   NF+ +    ++  + GES   +
Sbjct: 1467 TPSCSSVWASPA*RLPAVRTPGTGKTLLARAVASQLDCNFLKVVSSAIVDKYIGESARLI 1288

Query: 560  REIFDKARQAAPCVLFFDELDSIXXXXXXXXXXXXXXXDRVINQILTEMDGMSTKKNVFI 619
            RE+F  AR   PC++F DE+D+I                R + ++L +MDG      V +
Sbjct: 1287 REMFAFARDHEPCIIFMDEIDAIGGRRFSEGTSADREIQRTLMELLNQMDGFDALGQVKM 1108

Query: 620  IGATNRPDIIDPAILRPGRLDQLIYIPLPDEKSRVAILKANLRKSPVAK--DVDLEFLAK 677
            I ATNRPD +DPA+LRPGRLD+ I I LP+E++R+ ILK  +  +P+AK  ++D E + K
Sbjct: 1107 IMATNRPDTLDPALLRPGRLDRKIEISLPNEQARLEILK--IHANPIAKHGEIDWEAVVK 934

Query: 678  MTNGFSGADLTEICQRACKLA 698
            ++  F+GADL  +C  A   A
Sbjct: 933  LSEDFNGADLRNVCTEAGMFA 871

 Score = 37.0 bits (84), Expect = 0.035,   Method: Compositional matrix adjust.
 Identities = 27/102 (26%), Positives = 47/102 (46%), Gaps = 12/102 (11%)
 Frame = -1

Query: 446  AVTMDDFRWALSQSNPSALRETVVEVPQVTWEDIGGLEDVKRELQELVQYPVEHPDKFLK 505
             V +   R  +S  +P     +V +   +T+  IGGL +  REL+E+++ P+ +P+ F +
Sbjct: 1627 VVAIKKARSWISGMDPLVYNMSVEDPGDITFNQIGGLGEQVRELREVIELPLLNPELFQR 1448

Query: 506  FGMTPSKGVLFYGPP--------GCGKT----LLAKAIANEC 535
             G+T  K      P         GCG++    LL   +   C
Sbjct: 1447 VGITRLKAACCSDPRYWQDXAG*GCGQSAGL*LLEGGVQCHC 1322
>12235
          Length = 1749

 Score =  139 bits (349), Expect = 6e-33,   Method: Compositional matrix adjust.
 Identities = 68/167 (40%), Positives = 100/167 (59%), Gaps = 2/167 (1%)
 Frame = +1

Query: 534 ECQANFISIKGPELLTMWFGESEANVREIFDKARQAAPCVLFFDELDSIXXXXXXXXXXX 593
           E    FI++ G E L M+ G   + VR++F  AR+ APC+LF DE+D++           
Sbjct: 1   EANVPFITVSGSEFLEMFVGVGPSRVRDMFATARKNAPCILFVDEIDAVGRKRSGRNFGG 180

Query: 594 XXXXDRVINQILTEMDGMSTKKNVFIIGATNRPDIIDPAILRPGRLDQLIYIPLPDEKSR 653
               +  +NQ+L EMDG +T+  V ++ ATNR DI+D A+LRPGR D+ I++PLPD K R
Sbjct: 181 QSEQENTLNQLLVEMDGFNTQTGVVVLAATNRVDILDAALLRPGRFDRQIFVPLPDIKXR 360

Query: 654 VAILKANL--RKSPVAKDVDLEFLAKMTNGFSGADLTEICQRACKLA 698
            +I K +L   K+ V K+     +A +T GFSGAD+  +C  A  +A
Sbjct: 361 ASIFKVHLDPLKTEVNKNDLARKMAALTPGFSGADIANVCNEAALIA 501

 Score =  113 bits (282), Expect = 3e-25,   Method: Compositional matrix adjust.
 Identities = 84/262 (32%), Positives = 129/262 (49%), Gaps = 9/262 (3%)
 Frame = +1

Query: 266 FFLINGPEIMSKLAGESESNLRKAFEEAEKNAPAIIFIDELDAIAPKREKTH--GEVER- 322
           F  ++G E +    G   S +R  F  A KNAP I+F+DE+DA+  KR   +  G+ E+ 
Sbjct: 16  FITVSGSEFLEMFVGVGPSRVRDMFATARKNAPCILFVDEIDAVGRKRSGRNFGGQSEQE 195

Query: 323 RIVSQLLTLMDGLKQRAHVIVMAATNRPNSIDPALRRFGRFDREVDIGIPDATGRLEILQ 382
             ++QLL  MDG   +  V+V+AATNR + +D AL R GRFDR++ + +PD   R  I +
Sbjct: 196 NTLNQLLVEMDGFNTQTGVVVLAATNRVDILDAALLRPGRFDRQIFVPLPDIKXRASIFK 375

Query: 383 IHTKNMKL-ADDVDL-EQVANETHGHVGADLAALCSEAALQAIRKKMDLIDLEDETIDAE 440
           +H   +K   +  DL  ++A  T G  GAD+A +C+EAAL A R   DL           
Sbjct: 376 VHLDPLKTEVNKNDLARKMAALTPGFSGADIANVCNEAALIAAR---DL----------- 513

Query: 441 VMNSLAVTMDDFRWALSQSNPSALRETVVEVPQ----VTWEDIGGLEDVKRELQELVQYP 496
              + ++ M  F  A+ +      ++T V  P+    V + + G           +  + 
Sbjct: 514 ---NTSIHMTHFEQAIERVVAGLEKKTQVLQPEEKKTVAYHEAG---------HAVAGWY 657

Query: 497 VEHPDKFLKFGMTPSKGVLFYG 518
           +EH D  LK  + P    L Y 
Sbjct: 658 LEHADPLLKVSIIPRGKGLGYA 723
>00810
          Length = 1431

 Score =  125 bits (313), Expect = 8e-29,   Method: Compositional matrix adjust.
 Identities = 78/217 (35%), Positives = 120/217 (55%), Gaps = 3/217 (1%)
 Frame = -3

Query: 482  LEDVKRELQELVQYPVEHPDKFLKFGM-TPSKGVLFYGPPGCGKTLLAKAIANECQANFI 540
            LEDV ++++E V  P +  D F    +  P KGVL +GPPGCGKT++AKA A    A FI
Sbjct: 1429 LEDVIQDVKETVILPFKRADLFRHSSLLQPPKGVLLHGPPGCGKTMIAKATAKAAGARFI 1250

Query: 541  SIKGPELLTMWFGESEANVREIFDKARQAAPCVLFFDELDSIXXXXXXXXXXXXXXXDRV 600
            +++   L+  W+GES+     +F  A +  P ++F DE+DS                  +
Sbjct: 1249 NLQVSSLVDKWYGESQKRAEAVFSLAIKLQPTIIFIDEIDSFLRSRTSTDHEATAM---I 1079

Query: 601  INQILTEMDGMSTKKN--VFIIGATNRPDIIDPAILRPGRLDQLIYIPLPDEKSRVAILK 658
              Q ++  DG+ T  +  V ++GATNRP  +D AILR  R+  + +I LP    R +I  
Sbjct: 1078 KTQFMSFWDGLMTDPDCRVMVMGATNRPQDVDAAILR--RMPSMFHIGLPGPAQRRSIFN 905

Query: 659  ANLRKSPVAKDVDLEFLAKMTNGFSGADLTEICQRAC 695
              L K  +   ++ + LA+MT+GFSG+D+ E+C+ A 
Sbjct: 904  LILSKERIDA-LNYDELAEMTDGFSGSDIREVCRAAA 797

 Score =  115 bits (287), Expect = 8e-26,   Method: Compositional matrix adjust.
 Identities = 75/213 (35%), Positives = 112/213 (52%), Gaps = 3/213 (1%)
 Frame = -3

Query: 216  IKEMVELPLRHPALFKAIGV-KPPRGILLYGPPGTGKTLIARAVANETGAFFFLINGPEI 274
            +KE V LP +   LF+   + +PP+G+LL+GPPG GKT+IA+A A   GA F  +    +
Sbjct: 1408 VKETVILPFKRADLFRHSSLLQPPKGVLLHGPPGCGKTMIAKATAKAAGARFINLQVSSL 1229

Query: 275  MSKLAGESESNLRKAFEEAEKNAPAIIFIDELDAIAPKREKTHGEVERRIVSQLLTLMDG 334
            + K  GES+      F  A K  P IIFIDE+D+    R  T  E    I +Q ++  DG
Sbjct: 1228 VDKWYGESQKRAEAVFSLAIKLQPTIIFIDEIDSFLRSRTSTDHEATAMIKTQFMSFWDG 1049

Query: 335  LKQ--RAHVIVMAATNRPNSIDPALRRFGRFDREVDIGIPDATGRLEILQIHTKNMKLAD 392
            L       V+VM ATNRP  +D A+ R  R      IG+P    R  I  +     ++ D
Sbjct: 1048 LMTDPDCRVMVMGATNRPQDVDAAILR--RMPSMFHIGLPGPAQRRSIFNLILSKERI-D 878

Query: 393  DVDLEQVANETHGHVGADLAALCSEAALQAIRK 425
             ++ +++A  T G  G+D+  +C  AA+  + +
Sbjct: 877  ALNYDELAEMTDGFSGSDIREVCRAAAVATVHE 779
>20270
          Length = 542

 Score = 92.8 bits (229), Expect(2) = 1e-25,   Method: Compositional matrix adjust.
 Identities = 47/128 (36%), Positives = 71/128 (55%), Gaps = 2/128 (1%)
 Frame = -3

Query: 510 PSKGVLFYGPPGCGKTLLAKAIANECQ-ANFISIKGPELLTMWFGESEANVREIFDKARQ 568
           P +G+L YGPPG GK+ LAKA+A E   + F S+   +L++ W GESE  V+ +F  AR+
Sbjct: 384 PWRGILLYGPPGTGKSYLAKAVATEANNSTFFSVSSSDLVSKWLGESEKLVKTLFQLARE 205

Query: 569 AAPCVLFFDELDSIXXXXXXXXXXXXXXXDRVINQILTEMDGMST-KKNVFIIGATNRPD 627
             P ++F DE+D++                R+  + L +M G+      V ++GATN P 
Sbjct: 204 NQPSIIFIDEVDALCGSRSENESESAR---RIKTEFLVQMQGVGNDNTGVLVLGATNIPW 34

Query: 628 IIDPAILR 635
            +D AI R
Sbjct: 33  TLDSAIRR 10

 Score = 42.7 bits (99), Expect(2) = 1e-25,   Method: Composition-based stats.
 Identities = 20/42 (47%), Positives = 25/42 (59%)
 Frame = -1

Query: 462 SALRETVVEVPQVTWEDIGGLEDVKRELQELVQYPVEHPDKF 503
           SA+R  VVE P V W+D+ GL   K  L+E V  PV+ P  F
Sbjct: 524 SAVRSHVVEKPNVRWDDVAGLNGAKDALKEAVILPVKFPHLF 399

 Score =  114 bits (285), Expect = 2e-25,   Method: Compositional matrix adjust.
 Identities = 60/131 (45%), Positives = 86/131 (65%), Gaps = 2/131 (1%)
 Frame = -3

Query: 236 KPPRGILLYGPPGTGKTLIARAVANE-TGAFFFLINGPEIMSKLAGESESNLRKAFEEAE 294
           KP RGILLYGPPGTGK+ +A+AVA E   + FF ++  +++SK  GESE  ++  F+ A 
Sbjct: 387 KPWRGILLYGPPGTGKSYLAKAVATEANNSTFFSVSSSDLVSKWLGESEKLVKTLFQLAR 208

Query: 295 KNAPAIIFIDELDAIAPKREKTHGEVERRIVSQLLTLMDGL-KQRAHVIVMAATNRPNSI 353
           +N P+IIFIDE+DA+   R +   E  RRI ++ L  M G+      V+V+ ATN P ++
Sbjct: 207 ENQPSIIFIDEVDALCGSRSENESESARRIKTEFLVQMQGVGNDNTGVLVLGATNIPWTL 28

Query: 354 DPALRRFGRFD 364
           D A+RR  RF+
Sbjct: 27  DSAIRR--RFE 1
>02191
          Length = 1137

 Score = 99.8 bits (247), Expect = 4e-21,   Method: Compositional matrix adjust.
 Identities = 50/61 (81%), Positives = 54/61 (88%), Gaps = 2/61 (3%)
 Frame = +2

Query: 716 NPSA-MEVEEDDPVPEIRRDHFEEAMRFARRSVSDNDIRKYEMFAQTLQQSRGF-GSFRF 773
           NP A ME E+ DPVPEI R HFEEAM+FARRSV+DNDIRKYEMFAQTLQQSRGF G+FRF
Sbjct: 29  NPDADMETEDYDPVPEISRAHFEEAMKFARRSVTDNDIRKYEMFAQTLQQSRGFGGNFRF 208

Query: 774 P 774
           P
Sbjct: 209 P 211
>25671
          Length = 441

 Score = 82.0 bits (201), Expect = 9e-16,   Method: Composition-based stats.
 Identities = 48/108 (44%), Positives = 65/108 (60%), Gaps = 6/108 (5%)
 Frame = +2

Query: 249 TGKTLIARAVANETGAFFFLINGPEIMSKLAGESESNLRKAFEEAEKNAPAIIFIDELDA 308
           TGKT++A+AVA E G  FF ++   + +K  GESE  +R  FE A   AP+ IFIDE+D+
Sbjct: 2   TGKTMLAKAVATECGTTFFNVSTSSLANKYRGESEKLVRLLFEMAHFYAPSTIFIDEIDS 181

Query: 309 IAPKR-EKTHGEVERRIVSQLLTLMDGL-----KQRAHVIVMAATNRP 350
           I  KR   +  E  RR+ S+LL  MDG+          V+V+AATN P
Sbjct: 182 ICSKRGSDSEHEASRRVKSELLVQMDGVGVTNDDPSKAVMVLAATNFP 325

 Score = 67.4 bits (163), Expect(2) = 2e-14,   Method: Composition-based stats.
 Identities = 40/109 (36%), Positives = 56/109 (51%), Gaps = 5/109 (4%)
 Frame = +2

Query: 523 GKTLLAKAIANECQANFISIKGPELLTMWFGESEANVREIFDKARQAAPCVLFFDELDSI 582
           GKT+LAKA+A EC   F ++    L   + GESE  VR +F+ A   AP  +F DE+DSI
Sbjct: 5   GKTMLAKAVATECGTTFFNVSTSSLANKYRGESEKLVRLLFEMAHFYAPSTIFIDEIDSI 184

Query: 583 XXXXXXXXXXXXXXXDRVINQILTEMDGMST-----KKNVFIIGATNRP 626
                           RV +++L +MDG+        K V ++ ATN P
Sbjct: 185 CSKRGSDSEHEASR--RVKSELLVQMDGVGVTNDDPSKAVMVLAATNFP 325

 Score = 30.8 bits (68), Expect(2) = 2e-14,   Method: Compositional matrix adjust.
 Identities = 17/35 (48%), Positives = 24/35 (68%)
 Frame = +3

Query: 629 IDPAILRPGRLDQLIYIPLPDEKSRVAILKANLRK 663
           ID A+ R  RL++ IYIPLP  + R  +L+ NLR+
Sbjct: 333 IDEALRR--RLEKRIYIPLPSAEGRRVLLEINLRE 431
>26408
          Length = 463

 Score = 79.0 bits (193), Expect = 8e-15,   Method: Composition-based stats.
 Identities = 32/48 (66%), Positives = 43/48 (89%)
 Frame = +1

Query: 215 QIKEMVELPLRHPALFKAIGVKPPRGILLYGPPGTGKTLIARAVANET 262
           +IKE++ELP++HP LF A+G+  P+G+LLYGPPGTGKTL+ARAVA+ T
Sbjct: 295 RIKEVIELPVKHPELFDALGIAQPKGVLLYGPPGTGKTLLARAVAHHT 438

 Score = 60.1 bits (144), Expect = 3e-09,   Method: Composition-based stats.
 Identities = 24/52 (46%), Positives = 38/52 (73%)
 Frame = +1

Query: 487 RELQELVQYPVEHPDKFLKFGMTPSKGVLFYGPPGCGKTLLAKAIANECQAN 538
           + ++E+++ PV+HP+ F   G+   KGVL YGPPG GKTLLA+A+A+  + +
Sbjct: 292 QRIKEVIELPVKHPELFDALGIAQPKGVLLYGPPGTGKTLLARAVAHHTRVH 447
>17843
          Length = 772

 Score = 60.8 bits (146), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 49/191 (25%), Positives = 82/191 (42%), Gaps = 18/191 (9%)
 Frame = +1

Query: 476 WEDIGGLEDVKRELQELVQYPVEHPDKFLKFGM-TPSKGVLFYGPPGCGKTLLAKAIANE 534
           W+ +   E++K  L       +   DK +   + + ++ +L +GPPG GKT L KA+A++
Sbjct: 76  WDSLVFDENIKERLLNYATTTLLFSDKHVNSSIISWNRVILLHGPPGTGKTTLCKALAHK 255

Query: 535 ----------CQANFISIKGPELLTMWFGESEANVREIFDKAR------QAAPCVLFFDE 578
                     C    + I    L + WF ES   V ++F +        +   CVL  DE
Sbjct: 256 LCIRLSHRFSC-GQLVEINSHSLFSKWFSESGKLVTKMFQRLHDYMVDPELLVCVL-IDE 429

Query: 579 LDSIXXXXXXXXXXXX-XXXDRVINQILTEMDGMSTKKNVFIIGATNRPDIIDPAILRPG 637
           ++S+                 RV+N +LT++D +    N  I+  +N    ID A +   
Sbjct: 430 VESLTAARKSCLNGNEPSDAIRVVNAVLTQIDQLKKFANCLILTTSNITGAIDLAFVDRA 609

Query: 638 RLDQLIYIPLP 648
            + Q I  P P
Sbjct: 610 DIKQYIGPPTP 642

 Score = 55.5 bits (132), Expect = 8e-08,   Method: Compositional matrix adjust.
 Identities = 44/152 (28%), Positives = 73/152 (48%), Gaps = 18/152 (11%)
 Frame = +1

Query: 239 RGILLYGPPGTGKTLIARAVANE---------TGAFFFLINGPEIMSKLAGESESNLRKA 289
           R ILL+GPPGTGKT + +A+A++         +      IN   + SK   ES   + K 
Sbjct: 187 RVILLHGPPGTGKTTLCKALAHKLCIRLSHRFSCGQLVEINSHSLFSKWFSESGKLVTKM 366

Query: 290 FEE-----AEKNAPAIIFIDELDAIAPKREKTHGEVE----RRIVSQLLTLMDGLKQRAH 340
           F+       +      + IDE++++   R+      E     R+V+ +LT +D LK+ A+
Sbjct: 367 FQRLHDYMVDPELLVCVLIDEVESLTAARKSCLNGNEPSDAIRVVNAVLTQIDQLKKFAN 546

Query: 341 VIVMAATNRPNSIDPALRRFGRFDREVDIGIP 372
            +++  +N   +ID A     R D +  IG P
Sbjct: 547 CLILTTSNITGAIDLAF--VDRADIKQYIGPP 636
>25936
          Length = 459

 Score = 59.3 bits (142), Expect = 6e-09,   Method: Composition-based stats.
 Identities = 47/147 (31%), Positives = 72/147 (48%), Gaps = 8/147 (5%)
 Frame = +2

Query: 363 FDREVD-IGIPDATGRLEILQIHTKNMKLA------DDVDLEQVANETHGHVGADLAALC 415
           F +EV  I  PD  GR EILQ   K+          + +DL+ VA+ T G V  D+  L 
Sbjct: 8   FVQEVTTIKPPDKAGRQEILQCTLKSHSTVCARSTLERLDLDSVASRTEGFVARDIQTLV 187

Query: 416 SEAALQAIRKKMDLIDLEDETIDAEVMNSLAVTMDDFRWALSQSNPSALRETVVEVP-QV 474
           +    +A+  ++        T  AE  N++ +   DF  AL    P A+R   +    ++
Sbjct: 188 N----RALHARLA------ATPSAE-SNTVILQQTDFDTALEGFKPLAIRNVHLHTSGEL 334

Query: 475 TWEDIGGLEDVKRELQELVQYPVEHPD 501
            W D+GGLE VK  L E +Q+P ++P+
Sbjct: 335 GWSDVGGLEGVKSSLIETLQWPSKYPE 415
>02194
          Length = 1891

 Score = 53.9 bits (128), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 44/144 (30%), Positives = 65/144 (45%), Gaps = 6/144 (4%)
 Frame = -1

Query: 227  PALFKAIGVKPPRGILLYGPPGTGKTLIARAVANETGAFFFLINGPEIMSKLAGESESNL 286
            P  +   G+   RG LLYGPPG GK+    A+A        ++N  E      G S+  L
Sbjct: 1531 PRWYMDRGIPYRRGYLLYGPPGCGKSSYIMALAGALDYNICVLNLSE-----KGLSDDRL 1367

Query: 287  RKAFEEAEKNAPAIIFIDELDAIAPKREKT------HGEVERRIVSQLLTLMDGLKQRAH 340
                  A +   +II ++++DA    R+ +      +  + R   S LL  +DG+     
Sbjct: 1366 NHLLTVAPEQ--SIILLEDVDAAFLSRDLSKENPAMYQGMGRLTFSGLLNALDGVASAEA 1193

Query: 341  VIVMAATNRPNSIDPALRRFGRFD 364
             IV   TN  + +DPAL R GR D
Sbjct: 1192 RIVFMTTNYLDRLDPALIRPGRVD 1121

 Score = 52.0 bits (123), Expect = 9e-07,   Method: Compositional matrix adjust.
 Identities = 35/144 (24%), Positives = 67/144 (46%), Gaps = 3/144 (2%)
 Frame = -1

Query: 500  PDKFLKFGMTPSKGVLFYGPPGCGKTLLAKAIANECQANFISIKGPELLTMWFGESEANV 559
            P  ++  G+   +G L YGPPGCGK+    A+A     N   +   E      G S+  +
Sbjct: 1531 PRWYMDRGIPYRRGYLLYGPPGCGKSSYIMALAGALDYNICVLNLSEK-----GLSDDRL 1367

Query: 560  REIFDKARQAAPCVLFFDELDS--IXXXXXXXXXXXXXXXDRV-INQILTEMDGMSTKKN 616
              +   A + +  ++  +++D+  +                R+  + +L  +DG+++ + 
Sbjct: 1366 NHLLTVAPEQS--IILLEDVDAAFLSRDLSKENPAMYQGMGRLTFSGLLNALDGVASAEA 1193

Query: 617  VFIIGATNRPDIIDPAILRPGRLD 640
              +   TN  D +DPA++RPGR+D
Sbjct: 1192 RIVFMTTNYLDRLDPALIRPGRVD 1121
>29846
          Length = 451

 Score = 45.8 bits (107), Expect = 7e-05,   Method: Composition-based stats.
 Identities = 21/52 (40%), Positives = 31/52 (59%)
 Frame = +1

Query: 643 IYIPLPDEKSRVAILKANLRKSPVAKDVDLEFLAKMTNGFSGADLTEICQRA 694
           I I +P    R  I    LRK P+A D+DL++L+ +T G+ GAD+  +C  A
Sbjct: 142 ILISVPTSIQRRQIFNFCLRKLPLASDLDLDWLSSVTAGYVGADIKAVCASA 297

 Score = 43.5 bits (101), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 19/53 (35%), Positives = 34/53 (64%)
 Frame = +1

Query: 366 EVDIGIPDATGRLEILQIHTKNMKLADDVDLEQVANETHGHVGADLAALCSEA 418
           E+ I +P +  R +I     + + LA D+DL+ +++ T G+VGAD+ A+C+ A
Sbjct: 139 EILISVPTSIQRRQIFNFCLRKLPLASDLDLDWLSSVTAGYVGADIKAVCASA 297
>05247
          Length = 375

 Score = 33.9 bits (76), Expect(2) = 8e-04,   Method: Composition-based stats.
 Identities = 14/30 (46%), Positives = 22/30 (73%)
 Frame = +1

Query: 662 RKSPVAKDVDLEFLAKMTNGFSGADLTEIC 691
           +K P+ KDVD++ LA +T G +GAD+  +C
Sbjct: 73  KKMPLGKDVDVKQLADLTAG*TGADIKTLC 162

 Score = 27.7 bits (60), Expect(2) = 8e-04,   Method: Composition-based stats.
 Identities = 11/26 (42%), Positives = 17/26 (65%)
 Frame = +2

Query: 638 RLDQLIYIPLPDEKSRVAILKANLRK 663
           R+D+LIY+P PD + R+     + RK
Sbjct: 2   RMDRLIYVPPPDVQGRLQSFTIHTRK 79

 Score = 33.1 bits (74), Expect(2) = 0.002,   Method: Composition-based stats.
 Identities = 15/30 (50%), Positives = 20/30 (66%)
 Frame = +1

Query: 386 KNMKLADDVDLEQVANETHGHVGADLAALC 415
           K M L  DVD++Q+A+ T G  GAD+  LC
Sbjct: 73  KKMPLGKDVDVKQLADLTAG*TGADIKTLC 162

 Score = 26.6 bits (57), Expect(2) = 0.002,   Method: Composition-based stats.
 Identities = 11/25 (44%), Positives = 15/25 (60%)
 Frame = +2

Query: 362 RFDREVDIGIPDATGRLEILQIHTK 386
           R DR + +  PD  GRL+   IHT+
Sbjct: 2   RMDRLIYVPPPDVQGRLQSFTIHTR 76
>08000
          Length = 343

 Score = 39.3 bits (90), Expect = 0.006,   Method: Composition-based stats.
 Identities = 14/34 (41%), Positives = 24/34 (70%)
 Frame = +3

Query: 662 RKSPVAKDVDLEFLAKMTNGFSGADLTEICQRAC 695
           ++ P+ KDVD++ LA +T G++GAD+  +C   C
Sbjct: 15  QEMPLGKDVDVKQLADLTAGYTGADIKTLCNEGC 116

 Score = 39.3 bits (90), Expect = 0.006,   Method: Composition-based stats.
 Identities = 16/34 (47%), Positives = 24/34 (70%)
 Frame = +3

Query: 385 TKNMKLADDVDLEQVANETHGHVGADLAALCSEA 418
           T+ M L  DVD++Q+A+ T G+ GAD+  LC+E 
Sbjct: 12  TQEMPLGKDVDVKQLADLTAGYTGADIKTLCNEG 113
>01279
          Length = 2183

 Score = 38.9 bits (89), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 25/57 (43%), Positives = 32/57 (56%), Gaps = 5/57 (8%)
 Frame = -3

Query: 239  RGILLYGPPGTGKTLIARAVANETG--AFFFLINGPEIMSKLAGESE---SNLRKAF 290
            R +LL GPPGTGKT IA A+A E G    F  + G E+ S    ++E    N R+A 
Sbjct: 1914 RAVLLAGPPGTGKTAIALAIAQELGNKVPFCPMVGSEVYSSEIKKTEVLMENFRRAI 1744

 Score = 32.0 bits (71), Expect = 1.0,   Method: Compositional matrix adjust.
 Identities = 19/56 (33%), Positives = 28/56 (50%), Gaps = 2/56 (3%)
 Frame = -3

Query: 503  FLKFGMTPSKGVLFYGPPGCGKTLLAKAIANEC--QANFISIKGPELLTMWFGESE 556
             +K      + VL  GPPG GKT +A AIA E   +  F  + G E+ +    ++E
Sbjct: 1941 LIKTKKMAGRAVLLAGPPGTGKTAIALAIAQELGNKVPFCPMVGSEVYSSEIKKTE 1774
>15498
          Length = 769

 Score = 35.8 bits (81), Expect = 0.067,   Method: Compositional matrix adjust.
 Identities = 21/66 (31%), Positives = 35/66 (53%)
 Frame = -1

Query: 216 IKEMVELPLRHPALFKAIGVKPPRGILLYGPPGTGKTLIARAVANETGAFFFLINGPEIM 275
           + E   LPL  P++ +   +   + ILL GP G+GK ++  A+ NE GA  F ++   + 
Sbjct: 247 VTEFGILPLGSPSVHEQAPLT--KSILLAGPRGSGKKMLVHALCNEVGANLFDLSPANLA 74

Query: 276 SKLAGE 281
            K  G+
Sbjct: 73  GKYPGK 56
>19561
          Length = 474

 Score = 32.0 bits (71), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 23/72 (31%), Positives = 32/72 (44%), Gaps = 5/72 (6%)
 Frame = -1

Query: 242 LLYGPPGTGKTLIARAVANETGAFFFLINGP-----EIMSKLAGESESNLRKAFEEAEKN 296
           LL GPPG GKT +A  VA   G     +N       E+ S    E+ + +R       + 
Sbjct: 369 LLCGPPGLGKTTLAHIVAKHAGYNVVEMNASDDRSVEVFSNKI-EAATQMRAVMGADPR- 196

Query: 297 APAIIFIDELDA 308
            P  + IDE+D 
Sbjct: 195 -PNCLIIDEIDG 163

 Score = 29.3 bits (64), Expect = 7.1,   Method: Compositional matrix adjust.
 Identities = 20/72 (27%), Positives = 30/72 (41%), Gaps = 2/72 (2%)
 Frame = -1

Query: 512 KGVLFYGPPGCGKTLLAKAIANECQANFISIKGPE--LLTMWFGESEANVREIFDKARQA 569
           K  L  GPPG GKT LA  +A     N + +   +   + ++  + EA  +         
Sbjct: 378 KVALLCGPPGLGKTTLAHIVAKHAGYNVVEMNASDDRSVEVFSNKIEAATQMRAVMGADP 199

Query: 570 APCVLFFDELDS 581
            P  L  DE+D 
Sbjct: 198 RPNCLIIDEIDG 163
>27434
          Length = 472

 Score = 30.4 bits (67), Expect = 3.0,   Method: Compositional matrix adjust.
 Identities = 13/29 (44%), Positives = 16/29 (55%)
 Frame = +2

Query: 241 ILLYGPPGTGKTLIARAVANETGAFFFLI 269
           +   GPPG GKT I R++A   G  F  I
Sbjct: 170 LCFVGPPGVGKTSIGRSIATTLGREFHRI 256
>01793
          Length = 1739

 Score = 30.0 bits (66), Expect = 3.4,   Method: Compositional matrix adjust.
 Identities = 16/42 (38%), Positives = 23/42 (54%), Gaps = 3/42 (7%)
 Frame = -3

Query: 175  IVAPD---TVIHCEGEPIKREDEEESLNEVGYDDIGGCRKQL 213
            ++ PD   ++IH     IKRE     +N + YDD GG R +L
Sbjct: 1647 LILPDKHFSLIHSL*LQIKREKSHVCMNVICYDDSGGKRSEL 1522
>30736
          Length = 520

 Score = 29.6 bits (65), Expect = 5.2,   Method: Composition-based stats.
 Identities = 12/29 (41%), Positives = 19/29 (65%)
 Frame = -2

Query: 236 KPPRGILLYGPPGTGKTLIARAVANETGA 264
           +PP  + + GPP +GKT +   +AN+ GA
Sbjct: 129 RPPCKLAVLGPPLSGKTTLCHLLANKYGA 43
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|77404392|ref|NP_062750.2| staphylococcal nuclease
domain containing 1 [Mus musculus]
         (910 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

06128                                                                 439   e-124
02407                                                                 224   1e-58
24326                                                                 204   5e-58
04982                                                                  53   6e-07
21795                                                                  52   1e-06
34863                                                                  46   7e-05
03574                                                                  46   8e-05
17475                                                                  42   0.001
29083                                                                  35   0.091
36453                                                                  35   0.093
>06128
          Length = 1202

 Score =  439 bits (1129), Expect(2) = e-124,   Method: Compositional matrix adjust.
 Identities = 220/362 (60%), Positives = 272/362 (75%), Gaps = 2/362 (0%)
 Frame = +3

Query: 439 TCATVTIGGINIAEALVSKGLATVIRYRQDDDQRSSHYDELLAAEARAIKNGKGLHSKKE 498
           TC +V+IGGINIAEALVSKGLA V+RYRQDDDQRSSHYDELLAAEARA K G GL SKKE
Sbjct: 60  TCCSVSIGGINIAEALVSKGLARVVRYRQDDDQRSSHYDELLAAEARAEKKGVGLFSKKE 239

Query: 499 VPIHRVADISGDTQKAKQFLPFLQRAGRSEAVVEYVFSGSRLKLYLPKETCLITFLLAGI 558
            P+HRVADI+GD  KAKQFLPFLQRAGRS+AVVE+V SGSRL+L+LP+ETCLITFL++GI
Sbjct: 240 SPLHRVADIAGDVPKAKQFLPFLQRAGRSDAVVEFVASGSRLRLFLPRETCLITFLISGI 419

Query: 559 ECPRGARNLP-GLVQEGEPFSEEATLFTKELVLQRXXXXXXXSMDKAGNFIGWLHMDGAN 617
           +CP+G R LP G   E +P+ EEA LFTKE+ +QR       ++DK GNFIGWL++D  N
Sbjct: 420 DCPKGKRQLPSGQSFEADPYGEEALLFTKEICMQREVEVEVEAIDKGGNFIGWLYVDNTN 599

Query: 618 LSVLLVEQALSKVHFTAERSAYYKPLLSAEEAAKQRKEKVWAHYEERPVEEVMPVLEEKE 677
           LSV LVE  L+KVHFTAERS++YK LLSA+E AK  K K W+++EE   +EV    E  E
Sbjct: 600 LSVALVEAGLAKVHFTAERSSHYKTLLSAQERAKSAKLKTWSNFEE--PKEVEVAEEPVE 773

Query: 678 RSASYKPVFVTEITDDLHFYVQDVETGTQLEKLMENMRNDISSHPPVEGSYAPRRGEFCI 737
           R  +Y  V +TE+TDD  FY Q V+ G Q+E+LME MR ++ S+PP+ G+Y P+RG+ C 
Sbjct: 774 RKINYTKVIITEVTDDFTFYAQKVDNGPQVERLMEQMRQEMDSNPPLPGAYTPKRGDLCA 953

Query: 738 AKF-VDGEWYRARVEKVESPAKVHVFYIDYGNREILPSTRLGTLPPAFSTRVLPAQATEY 796
           AKF  D +WYRA+V+KV S  K  + +ID+GN+E + S  L  LP AF +   P QA EY
Sbjct: 954 AKFSADDQWYRAKVQKVHS-GKADILFIDFGNKESVASGSLAALPAAFLS--TPPQANEY 1124

Query: 797 AF 798
             
Sbjct: 1125VL 1130

 Score = 24.3 bits (51), Expect(2) = e-124,   Method: Compositional matrix adjust.
 Identities = 10/14 (71%), Positives = 12/14 (85%)
 Frame = +1

Query: 413 KKVNVTVDYIRPAS 426
           KKVNV VDYI+P +
Sbjct: 1   KKVNVEVDYIQPPN 42

 Score = 77.8 bits (190), Expect = 2e-14,   Method: Compositional matrix adjust.
 Identities = 65/224 (29%), Positives = 115/224 (51%), Gaps = 11/224 (4%)
 Frame = +3

Query: 120 GENIAESLVAEGLATRREGMRANNPEQNRLSECEE----QAKASKKG--MWSEGNGS-HT 172
           G NIAE+LV++GLA     +R    +  R S  +E    +A+A KKG  ++S+     H 
Sbjct: 84  GINIAEALVSKGLA---RVVRYRQDDDQRSSHYDELLAAEARAEKKGVGLFSKKESPLHR 254

Query: 173 IRDLKYTIENPRHFVDSHHQKP-VNAIIEHVRDGSVVRALLLPGHHLVTVMLSGIKCPTF 231
           + D+   +   + F+    +    +A++E V  GS +R  L     L+T ++SGI CP  
Sbjct: 255 VADIAGDVPKAKQFLPFLQRAGRSDAVVEFVASGSRLRLFLPRETCLITFLISGIDCPKG 434

Query: 232 RRETDGSETPE--PFAAEAKFFTESRLLQRDVQIILESC-HNQNLLGTILHPNGNITELL 288
           +R+    ++ E  P+  EA  FT+   +QR+V++ +E+     N +G +   N N++  L
Sbjct: 435 KRQLPSGQSFEADPYGEEALLFTKEICMQREVEVEVEAIDKGGNFIGWLYVDNTNLSVAL 614

Query: 289 LKEGFARCVDWSIAVYTRGAEKLRAAERFAKERRLRIWRDYVPP 332
           ++ G A+ V ++    +     L A ER AK  +L+ W ++  P
Sbjct: 615 VEAGLAK-VHFTAERSSHYKTLLSAQER-AKSAKLKTWSNFEEP 740
>02407
          Length = 2662

 Score =  224 bits (571), Expect = 1e-58,   Method: Compositional matrix adjust.
 Identities = 111/234 (47%), Positives = 153/234 (65%), Gaps = 4/234 (1%)
 Frame = -2

Query: 681  SYKPVFVTEITDDLHFYVQDVETGTQLEKLMENMRNDISSHPPVEGSYAPRRGEFCIAKF 740
            +Y  V +TE+TDD  FY Q V+ G Q+E+LME MR ++ S+PP+ G+Y P+RG+ C AKF
Sbjct: 2661 NYTKVIITEVTDDFTFYAQKVDNGPQVERLMEQMRQEMDSNPPLPGAYTPKRGDLCAAKF 2482

Query: 741  -VDGEWYRARVEKVESPAKVHVFYIDYGNREILPSTRLGTLPPAFSTRVLPAQATEYAFA 799
              D +WYRA+V+KV S  K  + +ID+GN+E + S  L  LP AF +   P QA EY+ A
Sbjct: 2481 SADDQWYRAKVQKVHS-GKADILFIDFGNKESVASGSLAALPAAFLS--TPPQANEYSLA 2311

Query: 800  FIQVPQD--EDARTDAVDSVVRDIQNTQCLLNVEHLSASCPHVTLQF-ADSKGDVGLGLV 856
             + +P D  ED + DAVD++ RDI N Q  +NVE+ S    +VT+    D  GDVGL L+
Sbjct: 2310 GVALPPDVVEDGKQDAVDALYRDIMNHQVQVNVEYRSGGVDYVTMMTEEDGTGDVGLALI 2131

Query: 857  KEGLVMVEVRKEKQFQKVITEYLNAQESAKSARLNLWRYGDFRADDADEFGYSR 910
             +G V+VE RKE++  K++ +Y NA + A   R N+W YGDFR DD  EFG SR
Sbjct: 2130 NDGYVLVEERKERRLAKLMADYKNALDEALKKRKNIWHYGDFREDDTREFGISR 1969
>24326
          Length = 1186

 Score =  204 bits (520), Expect(2) = 5e-58,   Method: Compositional matrix adjust.
 Identities = 113/230 (49%), Positives = 145/230 (63%), Gaps = 15/230 (6%)
 Frame = -2

Query: 72  DTPDEPWAFPAREFLRKKLIGKEVCFTIENKTPQGREYGMIYLGKDTNGENIAESLVAEG 131
           +T DEP+A+ AREFLRK    K     I   T   +  G+        GE++A S  A+ 
Sbjct: 645 ETKDEPFAWEAREFLRKS*XAK-----ISPSTWNTKSLGL--------GESMALSTWAKT 505

Query: 132 LATRR---------------EGMRANNPEQNRLSECEEQAKASKKGMWSEGNGSHTIRDL 176
           +  R                 G++ ++ +Q RL + EE A+A+KKG  ++ + S  +RD+
Sbjct: 504 MKGRT*QSR*LQKVW*MYVAWGLKKDDADQQRLLQLEETARAAKKGKHAD-DASTRVRDI 328

Query: 177 KYTIENPRHFVDSHHQKPVNAIIEHVRDGSVVRALLLPGHHLVTVMLSGIKCPTFRRETD 236
            + IENPRHF+DSHH KPV A+IEHVRDG  VRA LLP    VTVMLSGIKCP F+ E  
Sbjct: 327 TWIIENPRHFIDSHHSKPVEAVIEHVRDGCTVRAFLLPSFDYVTVMLSGIKCPMFKTE-G 151

Query: 237 GSETPEPFAAEAKFFTESRLLQRDVQIILESCHNQNLLGTILHPNGNITE 286
           G + PE FA E ++FTESRLLQR+V+IILE   NQNLLGT+LHPNGNITE
Sbjct: 150 GKQIPEQFAEECRYFTESRLLQREVKIILEGVSNQNLLGTVLHPNGNITE 1

 Score = 39.3 bits (90), Expect(2) = 5e-58,   Method: Compositional matrix adjust.
 Identities = 22/48 (45%), Positives = 27/48 (56%)
 Frame = -3

Query: 18  TVQRGIVKMVLSGCAIIVXXXXXXXXXXXXXINLSNIRAGNLARRAAA 65
           TV RGIVK VLSG  I++             + LSNI+A  LARRA +
Sbjct: 809 TVHRGIVKQVLSGDTIVIRGQPKGGPPPEKTLCLSNIQAPKLARRAKS 666

 Score =  142 bits (359), Expect = 5e-34,   Method: Compositional matrix adjust.
 Identities = 67/109 (61%), Positives = 84/109 (77%), Gaps = 1/109 (0%)
 Frame = -2

Query: 544  LPKETCLITFLLAGIECPRGARNLP-GLVQEGEPFSEEATLFTKELVLQRXXXXXXXSMD 602
            LP+ETCLITFL++GI+CP+G R LP G   E +P+ EEA LFTKE+ +QR       ++D
Sbjct: 1185 LPRETCLITFLISGIDCPKGKRQLPSGQSFEADPYGEEALLFTKEICMQREVEVEVEAID 1006

Query: 603  KAGNFIGWLHMDGANLSVLLVEQALSKVHFTAERSAYYKPLLSAEEAAK 651
            K GNFIGWL++D  NLSV LVE  L+KVHFTAERS++YK LLSA+E AK
Sbjct: 1005 KGGNFIGWLYVDNTNLSVALVEAGLAKVHFTAERSSHYKTLLSAQERAK 859

 Score = 73.6 bits (179), Expect = 3e-13,   Method: Compositional matrix adjust.
 Identities = 100/396 (25%), Positives = 169/396 (42%), Gaps = 21/396 (5%)
 Frame = -2

Query: 218  LVTVMLSGIKCPTFRRETDGSETPE--PFAAEAKFFTESRLLQRDVQIILESC-HNQNLL 274
            L+T ++SGI CP  +R+    ++ E  P+  EA  FT+   +QR+V++ +E+     N +
Sbjct: 1167 LITFLISGIDCPKGKRQLPSGQSFEADPYGEEALLFTKEICMQREVEVEVEAIDKGGNFI 988

Query: 275  GTILHPNGNITELLLKEGFARCVDWSIAVYTRGAEKLRAAERFAKERRLRIWRDYVPP-T 333
            G +   N N++  L++ G A+ V ++    +     L A ER AK           P   
Sbjct: 987  GWLYVDNTNLSVALVEAGLAK-VHFTAERSSHYKTLLSAQER-AKSTSFSYNHHGKPKHA 814

Query: 334  ANLDQKDKQF-----------VAKVMQVLNADAIVVKLNSGDYKTIHLSSIRPPRLEGDN 382
            AN   ++++             AK       D + VK     +    +SS  P +++  N
Sbjct: 813  ANCPPRNRETGLVR*HDRHSRSAKRGTTTREDTMFVK-----HPGTQVSS--PGQIQ--N 661

Query: 383  IQDKNKKLRPLYDIPYMFEAREFLRKKLIGKKVNVTVDYIRPASPATETVPAFSERTCAT 442
            I++  +      D P+ +EAREFLRK    K        I P++  T+++        +T
Sbjct: 660  IENSVET----KDEPFAWEAREFLRKS*XAK--------ISPSTWNTKSLGLGESMALST 517

Query: 443  V--TIGGINIAEALVSKGLATVIRYRQDDDQRSSHYDELLAAEARAIKNGKGLHSKKEVP 500
               T+ G       + K     + +    D         L   ARA K GK         
Sbjct: 516  WAKTMKGRT*QSR*LQKVW*MYVAWGLKKDDADQQRLLQLEETARAAKKGKHADDAST-- 343

Query: 501  IHRVADISGDTQKAKQFLPFLQRAGRSEAVVEYVFSGSRLKLYLPKETCLITFLLAGIEC 560
              RV DI+   +  + F+     +   EAV+E+V  G  ++ +L      +T +L+GI+C
Sbjct: 342  --RVRDITWIIENPRHFIDS-HHSKPVEAVIEHVRDGCTVRAFLLPSFDYVTVMLSGIKC 172

Query: 561  P----RGARNLPGLVQEGEPFSEEATLFTKELVLQR 592
            P     G + +P      E F+EE   FT+  +LQR
Sbjct: 171  PMFKTEGGKQIP------EQFAEECRYFTESRLLQR 82
>04982
          Length = 1215

 Score = 52.8 bits (125), Expect = 6e-07,   Method: Compositional matrix adjust.
 Identities = 41/135 (30%), Positives = 66/135 (48%), Gaps = 5/135 (3%)
 Frame = +1

Query: 673 LEEKERSASYKPVFVTEITDDLHFYVQDVE-TGTQLEKLMENMRNDISSHPPVEGSY--- 728
           + E E    +  VFV+ +    HF++Q V  T   L+K+ ++M +   S+P    +Y   
Sbjct: 217 IPEAEPVKEFMEVFVSAVEHAGHFWLQMVNTTALNLDKMTDDM-SLFYSNPDTAQTYRLT 393

Query: 729 APRRGEFCIAKFV-DGEWYRARVEKVESPAKVHVFYIDYGNREILPSTRLGTLPPAFSTR 787
             + G+   A F  D  WYRARV   E   KV ++Y D+G+  ++P   L  L   + + 
Sbjct: 394 EVKEGDVVAAAFAEDNMWYRARVVGFED-GKVDLYYFDFGDNGLVPEEALRELKAEYLS- 567

Query: 788 VLPAQATEYAFAFIQ 802
            LP QA E   A ++
Sbjct: 568 -LPVQAIECKLANVK 609
>21795
          Length = 605

 Score = 51.6 bits (122), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 42/138 (30%), Positives = 65/138 (47%), Gaps = 20/138 (14%)
 Frame = +3

Query: 687 VTEITDDLHFYVQ--DVETGTQLEKL--MENMRNDISSHPPVEGSYAPRRGEFCIAKFVD 742
           VTE+    HFY Q  D E  T L+ L  M N  N +S       +  P +   C A ++D
Sbjct: 126 VTEVVQCGHFYAQCMDHENITHLQTLLSMLNPCNKLSXL-----NTPPHKDMMCXAPYMD 290

Query: 743 G--EWYRARVEKVES--------PAKV---HVFYIDYGNREILPSTRLGTLPP---AFST 786
               +YRAR+E +++        P       VF++DYGNR+ +P  RL  LP    + S 
Sbjct: 291 EYEAYYRARIESLQTRTLLLRGIPTTTRVAQVFFVDYGNRDEIPLDRLRALPSEAFSISM 470

Query: 787 RVLPAQATEYAFAFIQVP 804
           + +  + TE   + ++ P
Sbjct: 471 QAIECELTEIRPSSVKCP 524
>34863
          Length = 634

 Score = 46.2 bits (108), Expect = 7e-05,   Method: Compositional matrix adjust.
 Identities = 29/78 (37%), Positives = 41/78 (52%), Gaps = 4/78 (5%)
 Frame = -3

Query: 733 GEFCIAKFV-DGEWYRARVEKV-ESPAKVHVFYIDYGNREILPSTRLGTLPPAFSTRVLP 790
           G+  + +F  D  WYR RVE+V E      +F+ DYGN+E    + L  +P  F  R LP
Sbjct: 269 GDVVLVEFSEDNLWYRGRVERVYEDGTTCSIFFTDYGNKEDKEISSLMVVPQQF--RALP 96

Query: 791 AQATEYAFAFI--QVPQD 806
           AQA     A +   VP++
Sbjct: 95  AQAIACQLAGLPESVPEE 42
>03574
          Length = 3150

 Score = 45.8 bits (107), Expect = 8e-05,   Method: Compositional matrix adjust.
 Identities = 34/96 (35%), Positives = 48/96 (50%), Gaps = 4/96 (4%)
 Frame = -3

Query: 714 MRNDISSHPPVEGSYA--PRRGEFCIAKFV-DGEWYRARVEK-VESPAKVHVFYIDYGNR 769
           M +D+++ P  + +    P  GE C A+F  D   YRA V K         V+Y+DYGN 
Sbjct: 847 MMDDLNASPGQDSALQELPAAGEMCAARFSQDDRLYRALVAKNYPHDQTTLVYYVDYGNS 668

Query: 770 EILPSTRLGTLPPAFSTRVLPAQATEYAFAFIQVPQ 805
           E++   RL  LP  F     PAQA   AF  + +P+
Sbjct: 667 EVVTLDRLLALPQKFQDT--PAQALR-AFINLDLPE 569

 Score = 44.7 bits (104), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 32/107 (29%), Positives = 51/107 (47%), Gaps = 1/107 (0%)
 Frame = -3

Query: 663  ERPVEEVMPVLEEKERSASYKPVFVTEITDDLHFYVQDVETGTQLEKLMENMRNDISSHP 722
            E+P  +V+P       + S  P+    I +D   Y  D E   +   L++ +     +  
Sbjct: 1651 EQPDCDVLPHPHPPSNTLSVLPM---HIDNDGIIYAHDCEEEXKSTALLDLIDEYAKTEA 1481

Query: 723  PVEGSYAPRRGEFCIAKF-VDGEWYRARVEKVESPAKVHVFYIDYGN 768
            P +G    + G+ C+A F +D  WYRARV +V     V V Y+D+GN
Sbjct: 1480 P-KGQLKVKVGQICLAHFSIDNAWYRARVLEVTQ-KDVKVKYVDFGN 1346

 Score = 33.5 bits (75), Expect = 0.44,   Method: Compositional matrix adjust.
 Identities = 15/39 (38%), Positives = 22/39 (56%)
 Frame = -2

Query: 742  DGEWYRARVEKVESPAKVHVFYIDYGNREILPSTRLGTL 780
            D  WYRA +  V   A   V  +D+G+ + +PS+RL  L
Sbjct: 2369 DDRWYRATITAVLHDAVYQVSLVDFGHADTVPSSRLRXL 2253
>17475
          Length = 884

 Score = 42.0 bits (97), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 45/172 (26%), Positives = 70/172 (40%), Gaps = 1/172 (0%)
 Frame = -3

Query: 737 IAKFVDGEWYRARVEKVESPAKVHVFYIDYGNREILPSTRLGTLPPAFSTRVLPAQATEY 796
           ++    GEW+R+ V ++ S ++VHV + DYGN  +L  + L  LP        P    + 
Sbjct: 579 LSGLFQGEWFRSEVTEIVS-SQVHVTFFDYGNEAVLDLSDLCPLPKEL-CHSFPLATVKC 406

Query: 797 AFAFIQVPQDEDARTDAVDSVVRD-IQNTQCLLNVEHLSASCPHVTLQFADSKGDVGLGL 855
               I  P   D   +   SV R  ++N    + V+ +      V +   +S  DV   L
Sbjct: 405 CIDGIG-PAGGDTWDEECISVTRSLLENQPVAVTVKSVKEDMRSVMVINQNSNQDVAQLL 229

Query: 856 VKEGLVMVEVRKEKQFQKVITEYLNAQESAKSARLNLWRYGDFRADDADEFG 907
           V+EG  +    ++   QK        +  AK A L      DFR   A   G
Sbjct: 228 VQEGKAVSLPAEQTDAQKEELMRQMQELQAKMAALGTK*SKDFRNSSALRLG 73
>29083
          Length = 710

 Score = 35.4 bits (80), Expect = 0.091,   Method: Composition-based stats.
 Identities = 28/91 (30%), Positives = 44/91 (48%), Gaps = 5/91 (5%)
 Frame = -1

Query: 685 VFVTEITDDLHFYVQDVETGTQ--LEKLMENMRNDISSHPPVEGSYAPRRGEFCIAKFV- 741
           + VT I      + QD+   +Q  +E +   +     + P ++G   P  G+   A+F  
Sbjct: 296 MMVTFIETPTLLWCQDLTLTSQNEVELIATKLAEICPTAPKLQGR--PEPGKMYGAQFSE 123

Query: 742 DGEWYRA--RVEKVESPAKVHVFYIDYGNRE 770
           DGEWYR   R+    +  KV + YID+GN E
Sbjct: 122 DGEWYRCQLRMNIANNQDKVKIQYIDFGNCE 30
>36453
          Length = 667

 Score = 35.4 bits (80), Expect = 0.093,   Method: Composition-based stats.
 Identities = 26/71 (36%), Positives = 40/71 (56%), Gaps = 3/71 (4%)
 Frame = +2

Query: 707 LEKLMENMRNDISSHPPVEGSYAPRRGEFCIAKFVDGEWYRARVEKVESPA--KVHVFYI 764
           LE+L  ++ N   S+P V     P  G    A   +G+WYRA+V +V +PA  +  + Y+
Sbjct: 32  LERL-NHIMNLCYSNPSVPTLPLPVEGGVICAAESEGQWYRAQVMQV-NPADDQCEIRYL 205

Query: 765 DYGN-REILPS 774
           DYG  R+ +PS
Sbjct: 206 DYGGVRDCVPS 238
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|83816893|ref|NP_031866.2| DEAD (Asp-Glu-Ala-Asp) box
polypeptide 5 [Mus musculus]
         (615 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

04883                                                                 441   e-124
09327                                                                 372   e-103
00621                                                                 278   6e-75
01517                                                                 218   4e-57
30136                                                                 202   4e-52
01062                                                                 189   2e-48
09316                                                                 166   4e-41
19172                                                                 160   2e-39
02054                                                                  99   2e-34
00162                                                                 113   2e-30
07310                                                                 126   2e-29
00739                                                                 126   3e-29
12121                                                                 121   1e-27
02498                                                                  71   2e-26
33025                                                                 108   4e-25
14337                                                                 104   1e-22
22006                                                                  97   2e-20
08036                                                                  65   3e-20
34134                                                                  94   2e-19
19640                                                                  92   9e-19
12995                                                                  89   5e-18
34295                                                                  84   1e-16
17544                                                                  79   4e-15
00617                                                                  78   1e-14
17708                                                                  77   2e-14
19525                                                                  74   1e-13
11624                                                                  74   2e-13
39583                                                                  69   6e-12
11160                                                                  65   7e-11
10649                                                                  64   1e-10
03381                                                                  55   1e-07
19151                                                                  54   2e-07
31220                                                                  52   5e-07
33083                                                                  50   3e-06
11423                                                                  46   4e-05
06438                                                                  44   2e-04
31899                                                                  41   0.001
01821                                                                  38   0.014
22529                                                                  29   6.2  
>04883
          Length = 1155

 Score =  441 bits (1133), Expect(2) = e-124,   Method: Compositional matrix adjust.
 Identities = 199/311 (63%), Positives = 246/311 (79%)
 Frame = +3

Query: 37  PGEKLVKKKWNLDELPKFEKNFYQEHPDLARRTAQEVDTYRRSKEITVRGHNCPKPVLNF 96
           PG  L K KW++ +L  F+KNFY+E P  A R   E+D YR+S +I+V G   P P+L F
Sbjct: 189 PGGNLRKPKWDMSKLTPFQKNFYKESPTTASRNPMELDEYRQSHQISVSGKFVPNPILTF 368

Query: 97  YEANFPANVMDVIARQNFTEPTAIQAQGWPVALSGLDMVGVAQTGSGKTLSYLLPAIVHI 156
            E NFP  VM+ + R ++T PT IQ+Q WPVA++G D+VG+AQTGSGKTL+++LPAIVHI
Sbjct: 369 TEVNFPDYVMNQVRRNSWTAPTPIQSQSWPVAMAGKDLVGIAQTGSGKTLAFMLPAIVHI 548

Query: 157 NHQPFLERGDGPICLVLAPTRELXXXXXXXXXEYCRACRLKSTCIYGGAPKGPQIRDLER 216
           NHQ +LERGDGPI L L PTREL         E+  A R++S C+YGGAP+GPQ+RDLER
Sbjct: 549 NHQAYLERGDGPIVLALVPTRELAQQVQEVAQEFGHASRVRSVCVYGGAPRGPQLRDLER 728

Query: 217 GVEICIATPGRLIDFLECGKTNLRRTTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTL 276
           G EICIATPGRLIDFLE  +TNLRR TYLVLDEADRMLDMGFEPQIRKI++QIRPDRQTL
Sbjct: 729 GAEICIATPGRLIDFLESNRTNLRRCTYLVLDEADRMLDMGFEPQIRKIIEQIRPDRQTL 908

Query: 277 MWSATWPKEVRQLAEDFLKDYIHINIGALELSANHNILQIVDVCHDVEKDEKLIRLMEEI 336
           MWSATWPKEVR+LAEDF+ +Y+ +NIGALEL+ANHNILQI+DVC + EK++KL++L+ EI
Sbjct: 909 MWSATWPKEVRKLAEDFIDEYVQVNIGALELTANHNILQIIDVCMEHEKEDKLVKLLNEI 1088

Query: 337 MSEKENKTIVF 347
           M+ K+     F
Sbjct: 1089MTRKKRTKPSF 1121

 Score = 23.9 bits (50), Expect(2) = e-124,   Method: Compositional matrix adjust.
 Identities = 8/11 (72%), Positives = 11/11 (100%)
 Frame = +1

Query: 347  FVETKRRCDEL 357
            FVETKR+CD++
Sbjct: 1120 FVETKRKCDDI 1152
>09327
          Length = 1087

 Score =  372 bits (956), Expect = e-103,   Method: Compositional matrix adjust.
 Identities = 167/234 (71%), Positives = 204/234 (87%)
 Frame = +2

Query: 172 VLAPTRELXXXXXXXXXEYCRACRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDF 231
           +L PTREL         E+  + R++S C+YGGA +GPQ+R+L+RG EICIATPGRLIDF
Sbjct: 20  LLVPTRELAQQVQEVAVEFGHSSRVRSVCVYGGAQRGPQLRELDRGAEICIATPGRLIDF 199

Query: 232 LECGKTNLRRTTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAE 291
           LE  +TNLRR TYLVLDEADRMLDMGFEPQIRKIV+QIRPDRQTLMWSATWPKEVR+LAE
Sbjct: 200 LESNRTNLRRCTYLVLDEADRMLDMGFEPQIRKIVEQIRPDRQTLMWSATWPKEVRKLAE 379

Query: 292 DFLKDYIHINIGALELSANHNILQIVDVCHDVEKDEKLIRLMEEIMSEKENKTIVFVETK 351
           DF+ +Y  INIGAL+L+ANHNILQI+DVC D EK+EKL++L+ EIM EKEN+T++FVETK
Sbjct: 380 DFIMEYTQINIGALQLTANHNILQIIDVCMDHEKEEKLVKLLNEIMQEKENRTLIFVETK 559

Query: 352 RRCDELTRKMRRDGWPAMGIHGDKSQQERDWVLNEFKHGKAPILIATDVASRGL 405
           R+CD++ R+M+RDGWP + IHGDKSQQERDWVLN+F++G+ P+L+ATDVASRGL
Sbjct: 560 RKCDDIHRRMKRDGWPVLCIHGDKSQQERDWVLNDFRNGRCPVLLATDVASRGL 721
>00621
          Length = 2263

 Score =  278 bits (710), Expect = 6e-75,   Method: Compositional matrix adjust.
 Identities = 163/460 (35%), Positives = 251/460 (54%), Gaps = 31/460 (6%)
 Frame = +1

Query: 32  KKFGNPGEKLVKKKWNLDELPKFEKNFYQEHPDLARRTAQEVD--TYRRSKEITVRGHNC 89
           K+  N  +K  K+KW+            +   D A+    E D   +R    I+ +G   
Sbjct: 94  KRLKNMAKKEAKQKWD-----------DRHWTDKAKEEMAERDWRIFREDYNISCKGGRI 240

Query: 90  PKPVLNFYEANFPANVMDVIARQNFTEPTAIQAQGWPVALSGLDMVGVAQTGSGKTLSYL 149
           P P+  + E++  A++M+VI R  + EPT IQ Q  P+ L   D++GVA+TGSGKT ++L
Sbjct: 241 PNPIRFWKESDLGADIMEVIDRVGYKEPTPIQMQAIPIGLQNRDIIGVAETGSGKTAAFL 420

Query: 150 LPAIVHINHQPFLERGD----GPICLVLAPTRELXXXXXXXXXEYCRACRLKSTCIYGGA 205
           +P +V I   P +ER +    GP  ++LAPTREL         ++     ++   + GG 
Sbjct: 421 IPLLVWIQSLPKIERLEDADQGPYAVILAPTRELAQQIEEETRKFGEGLGIRVVSVIGGI 600

Query: 206 PKGPQIRDLERGVEICIATPGRLIDFLECGKTNLRRTTYLVLDEADRMLDMGFEPQIRKI 265
            +  Q   L++G E+ IATPGR+ID LE     L + TY+V+DEADRM++MGFEP++RKI
Sbjct: 601 SREEQGFKLQQGCEVVIATPGRMIDVLENRYLVLNQCTYVVMDEADRMINMGFEPEVRKI 780

Query: 266 VDQI-----RPD--------------------RQTLMWSATWPKEVRQLAEDFLKDYIHI 300
           +D +     +PD                    RQT+M++AT P +V +LA  FL+    +
Sbjct: 781 LDYLPVSNQKPDNDDAEDDLKMLQNFKSKHKYRQTVMFTATMPPQVERLARTFLRRPTVV 960

Query: 301 NIGALELSANHNILQIVDVCHDVEKDEKLIRLMEEIMSEKENKTIVFVETKRRCDELTRK 360
            IG +       + QIV +  + EK +KLI ++    +  +   I+FV  K+  D L + 
Sbjct: 961 YIGNVGKPVER-VEQIVYMLTESEKRKKLIEVLN---AGVDPPIIIFVNQKKGADVLAKS 1128

Query: 361 MRRDGWPAMGIHGDKSQQERDWVLNEFKHGKAPILIATDVASRGLDVEDVKFVINYDYPN 420
           + + G+ A  +HG K Q++R++ L   K G   I++ATDVA RG+D++DV  V+NYD   
Sbjct: 1129LEKMGFNATTLHGGKGQEQREYALASLKGGAKDIMVATDVAGRGIDIKDVSLVLNYDMAR 1308

Query: 421 SSEDYIHRIGRTARSTKTGTAYTFFTPNNIKQVSDLISVL 460
           + EDY HRIGRT R+ K GT+ TF T  +     DL  ++
Sbjct: 1309TIEDYTHRIGRTGRAGKEGTSITFLTKEDSMVFYDLKQLM 1428
>01517
          Length = 2605

 Score =  218 bits (556), Expect = 4e-57,   Method: Compositional matrix adjust.
 Identities = 117/243 (48%), Positives = 160/243 (65%), Gaps = 4/243 (1%)
 Frame = +2

Query: 229 IDFLECGKTNLRRTTYLVLDEADRMLDMGFEPQIRKIV--DQIRP--DRQTLMWSATWPK 284
           +D +E GK  +    YLVLDEADRMLDMGFEPQIR+IV  D + P   RQTLM+SAT+PK
Sbjct: 2   VDMMERGKIGMDHCNYLVLDEADRMLDMGFEPQIRRIVEKDTMPPTGQRQTLMFSATFPK 181

Query: 285 EVRQLAEDFLKDYIHINIGALELSANHNILQIVDVCHDVEKDEKLIRLMEEIMSEKENKT 344
           E++ LA DFL +YI + +G +  S + NI Q V    + EK   L+ L+    +  E+ T
Sbjct: 182 EIQLLARDFLDNYIFLAVGRVG-STSENITQKVVWVEEPEKRSFLLDLLMASGTGPESLT 358

Query: 345 IVFVETKRRCDELTRKMRRDGWPAMGIHGDKSQQERDWVLNEFKHGKAPILIATDVASRG 404
           +VFVETK+  D L + +  + +PA  IHGD+SQ+ER+  L  FK+G  PIL+AT VA+RG
Sbjct: 359 LVFVETKKGADSLEQFLMYENYPATSIHGDRSQREREDALRVFKNGDRPILVATAVAARG 538

Query: 405 LDVEDVKFVINYDYPNSSEDYIHRIGRTARSTKTGTAYTFFTPNNIKQVSDLISVLREAN 464
           LD+ +V+ VIN+D P+  E+Y+HRIGRT R    G A +FF   N     D++ +L EAN
Sbjct: 539 LDIPNVRHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNDKNRNIARDMLDLLTEAN 718

Query: 465 QAI 467
           Q +
Sbjct: 719 QEV 727
>30136
          Length = 524

 Score =  202 bits (513), Expect = 4e-52,   Method: Compositional matrix adjust.
 Identities = 98/174 (56%), Positives = 123/174 (70%)
 Frame = +2

Query: 51  LPKFEKNFYQEHPDLARRTAQEVDTYRRSKEITVRGHNCPKPVLNFYEANFPANVMDVIA 110
           L  F++NFYQEHP +A RT  EV  YR   EITVRG     P+ +F EA  P  V+  I 
Sbjct: 5   LTPFKRNFYQEHPTVANRTPYEVQRYRDEHEITVRGQAA-NPIQDFAEAYLPDYVIKEIR 181

Query: 111 RQNFTEPTAIQAQGWPVALSGLDMVGVAQTGSGKTLSYLLPAIVHINHQPFLERGDGPIC 170
           RQ +  PT IQAQGWP+A+SG + VG+A+TGSGKTL Y+LPAIVHIN+Q  L+RG+GPI 
Sbjct: 182 RQGYKSPTPIQAQGWPIAMSGANFVGIAKTGSGKTLGYILPAIVHINNQQPLQRGEGPIA 361

Query: 171 LVLAPTRELXXXXXXXXXEYCRACRLKSTCIYGGAPKGPQIRDLERGVEICIAT 224
           LVLAPTREL         E+  +  +++TC++GGAPKG Q+RDL+RG EI IAT
Sbjct: 362 LVLAPTRELAQQIQQVATEFGSSSYVRNTCVFGGAPKGGQMRDLQRGCEIVIAT 523
>01062
          Length = 2138

 Score =  189 bits (481), Expect = 2e-48,   Method: Compositional matrix adjust.
 Identities = 113/343 (32%), Positives = 178/343 (51%)
 Frame = -3

Query: 114  FTEPTAIQAQGWPVALSGLDMVGVAQTGSGKTLSYLLPAIVHINHQPFLERGDGPICLVL 173
            F +P+AIQ +     + G D++  AQ+G+GKT ++ +  +  ++ Q    +      L+L
Sbjct: 2019 FEKPSAIQQRAVKPIVKGRDVIAQAQSGTGKTATFSISVLQCLDIQLRETQA-----LIL 1855

Query: 174  APTRELXXXXXXXXXEYCRACRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLE 233
            +PTREL                ++     GG   G  IR L+ G  I   TPGR+ D ++
Sbjct: 1854 SPTRELATQIQKVMLALGDYMNVQCHSCIGGTNIGEDIRKLDYGQHIVSGTPGRVFDMIK 1675

Query: 234  CGKTNLRRTTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDF 293
                  R    ++LDEAD ML+ GF+ QI  +   + P  Q ++ SAT P E+ ++   F
Sbjct: 1674 RRNLRTRSIKMMILDEADEMLNKGFKEQIYDVYRYLPPATQVILISATLPHEILEMTNKF 1495

Query: 294  LKDYIHINIGALELSANHNILQIVDVCHDVEKDEKLIRLMEEIMSEKENKTIVFVETKRR 353
            + D I I +   EL+        V V  +  K + L  L + +      + ++F  TKR+
Sbjct: 1494 MTDPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTI---TQAVIFCNTKRK 1324

Query: 354  CDELTRKMRRDGWPAMGIHGDKSQQERDWVLNEFKHGKAPILIATDVASRGLDVEDVKFV 413
             D LT KMR   +    +HGD  Q+ER+ ++  F+ G + +LI TDV +RG+DV+ V  V
Sbjct: 1323 VDWLTEKMREANFTVSSMHGDMPQKEREAIMKVFRAGDSRVLITTDVWARGIDVQQVSLV 1144

Query: 414  INYDYPNSSEDYIHRIGRTARSTKTGTAYTFFTPNNIKQVSDL 456
            INYD PN+ E YIHRIGR+ R  + G A  F   ++I+ + D+
Sbjct: 1143 INYDLPNNRELYIHRIGRSGRFGRKGVAINFVKNDDIRILRDI 1015
>09316
          Length = 2312

 Score =  166 bits (419), Expect = 4e-41,   Method: Compositional matrix adjust.
 Identities = 102/340 (30%), Positives = 172/340 (50%), Gaps = 4/340 (1%)
 Frame = +2

Query: 114  FTEPTAIQAQGWPVALSGLDMVGVAQTGSGKTLSYLLPAIVHINHQPFLERGDGPI-CLV 172
            F  P+ +Q +  P A+  +D++  A++G GKT  ++L  +        LE  DG +  LV
Sbjct: 905  FEHPSEVQHECIPQAILSMDVLCQAKSGMGKTAVFVLATLQQ------LEPVDGQVSVLV 1066

Query: 173  LAPTRELXXXXXXXXXEYCRACR-LKSTCIYGGAPKGPQIRDLERGV-EICIATPGRLID 230
            +A TREL          + +    +K    +GG         L +    I + TPGRL  
Sbjct: 1067 MAHTRELAFQISKEYERFSKYMNNVKIAVFFGGMSVKKDEEVLSKNCPHIVVGTPGRLHA 1246

Query: 231  FLECGKTNLRRTTYLVLDEADRML-DMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQL 289
              +    NL++  + +LDE D+ML D+     +++I      ++Q +M+SAT  KE+R +
Sbjct: 1247 LAKANNLNLKKIKHFILDECDKMLADLDMRRDVQEIFRLTPHEKQVMMFSATLSKEIRPI 1426

Query: 290  AEDFLKDYIHINIGALELSANHNILQIVDVCHDVEKDEKLIRLMEEIMSEKENKTIVFVE 349
             + F++D + + +        H + Q      D EK+ KL  L++ +   + N+ I+FV+
Sbjct: 1427 CKKFMQDPMEVYVDDDSKLTLHGLQQHYCKLKDNEKNRKLFELLDVL---EFNQVIIFVK 1597

Query: 350  TKRRCDELTRKMRRDGWPAMGIHGDKSQQERDWVLNEFKHGKAPILIATDVASRGLDVED 409
            +  RC  L++ +    +PA+ IH   +Q+ER     +FK  +  IL+AT++  RG+D+E 
Sbjct: 1598 SVPRCMALSQLLLEQNFPAIAIHRQMTQEERLSRYQQFKDFQKRILVATNLFGRGMDIER 1777

Query: 410  VKFVINYDYPNSSEDYIHRIGRTARSTKTGTAYTFFTPNN 449
            V  V NYD P  S+ Y+HR+ R  R    G A TF +  N
Sbjct: 1778 VNIVFNYDMPEDSDTYLHRVARAGRFGTKGLAITFVSDEN 1897
>19172
          Length = 484

 Score =  160 bits (404), Expect = 2e-39,   Method: Composition-based stats.
 Identities = 73/114 (64%), Positives = 92/114 (80%)
 Frame = -1

Query: 292 DFLKDYIHINIGALELSANHNILQIVDVCHDVEKDEKLIRLMEEIMSEKENKTIVFVETK 351
           +FL +YI +NIG+L LSANHNILQIVDVC + EK  KLI+L+ +I  E E KTI+FVETK
Sbjct: 484 EFLNNYIQVNIGSLSLSANHNILQIVDVCDESEKIAKLIQLLTQISGENETKTIIFVETK 305

Query: 352 RRCDELTRKMRRDGWPAMGIHGDKSQQERDWVLNEFKHGKAPILIATDVASRGL 405
           +R DE+TR + R GW A  IHGDKSQQERD+VL+ F++G+  IL+ATDVA+RGL
Sbjct: 304 KRVDEITRNISRQGWRACAIHGDKSQQERDFVLSSFRNGRHSILVATDVAARGL 143
>02054
          Length = 1110

 Score = 99.4 bits (246), Expect(2) = 2e-34,   Method: Compositional matrix adjust.
 Identities = 52/127 (40%), Positives = 76/127 (59%)
 Frame = -3

Query: 325 KDEKLIRLMEEIMSEKENKTIVFVETKRRCDELTRKMRRDGWPAMGIHGDKSQQERDWVL 384
           KD  L+ ++ E+     N  +VF  T      +   +R  G+ A+ +HG  SQ +R   L
Sbjct: 679 KDAYLVSILNELAG---NSFMVFCSTCANTQRVALLLRNLGFTAIPLHGQMSQAKRLGSL 509

Query: 385 NEFKHGKAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYIHRIGRTARSTKTGTAYTF 444
           N+FK     ILIATDVASRGLD+  V  V+N D P  S+DY+HR+GRTAR+ ++G A TF
Sbjct: 508 NKFKSKDRSILIATDVASRGLDIPHVDVVLNLDIPTHSKDYMHRVGRTARAGRSGRAITF 329

Query: 445 FTPNNIK 451
            +  +++
Sbjct: 328 VSQYDVE 308

 Score = 65.5 bits (158), Expect(2) = 2e-34,   Method: Compositional matrix adjust.
 Identities = 34/68 (50%), Positives = 47/68 (69%), Gaps = 1/68 (1%)
 Frame = -2

Query: 220 ICIATPGRLIDFLECGK-TNLRRTTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMW 278
           I IATPGRL+D LE  K  +LR   +LV+DEADR+LDM F+ ++ KI+  I  +R T ++
Sbjct: 995 IIIATPGRLVDHLENTKGFSLRALKFLVMDEADRILDMNFQDEVDKILKVIPRERNTYLF 816

Query: 279 SATWPKEV 286
           SAT   +V
Sbjct: 815 SATMTNKV 792
>00162
          Length = 2322

 Score =  113 bits (282), Expect(2) = 2e-30,   Method: Compositional matrix adjust.
 Identities = 93/283 (32%), Positives = 133/283 (46%), Gaps = 5/283 (1%)
 Frame = +3

Query: 171 LVLAPTRELXXXXXXXXXEYCRACRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLID 230
           L++ PTREL         +        +  + GG     +   L     I I T GRL+ 
Sbjct: 147 LIITPTRELAFQIYEVLNKIRTFHDFSANLVIGGKFMWRET-HLMGKTNIVICTVGRLLH 323

Query: 231 FLECGKT-NLRRTTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQL 289
            LE  +  ++     LVLDEADR++D  F   +  I+  + P RQTL++SAT    V+ L
Sbjct: 324 HLESTQAFDVSELKVLVLDEADRIMDSKFAQDMDSIMSHL-PPRQTLLFSATQTMSVKTL 500

Query: 290 AEDFLKD--YIHINIGALELSANHNILQIVDVCHDVEKDEKLIRLMEEIMSEKENKTIVF 347
           A   LKD  Y+ ++  A E      + Q   VC   E  EKL  L   + +   NK +VF
Sbjct: 501 ARLSLKDPSYVSVDRHA-EYVTPTGLEQSYIVC---ELHEKLSLLYSFLKNHPNNKIMVF 668

Query: 348 VETKRRCDELTRKMRRD--GWPAMGIHGDKSQQERDWVLNEFKHGKAPILIATDVASRGL 405
           ++T ++   +   ++R+  G   + +HG   Q  R  +  EF   +  ILI TD+A RGL
Sbjct: 669 LQTCKQARYVHTVIKRERPGMSVLVLHGGIPQLRRLDIYREFCRKQHVILITTDLACRGL 848

Query: 406 DVEDVKFVINYDYPNSSEDYIHRIGRTARSTKTGTAYTFFTPN 448
           D   V +VI  D P     YIHR GRTAR    G A     P+
Sbjct: 849 DFPAVNWVIQLDCPVDVNTYIHRAGRTARFECNGQALLVLLPS 977

 Score = 38.1 bits (87), Expect(2) = 2e-30,   Method: Compositional matrix adjust.
 Identities = 16/37 (43%), Positives = 27/37 (72%)
 Frame = +2

Query: 127 VALSGLDMVGVAQTGSGKTLSYLLPAIVHINHQPFLE 163
           +A  GLD++G A+TGSGKTL++L+P +  ++ Q  + 
Sbjct: 20  LACRGLDVLGAAKTGSGKTLAFLIPILETLSKQDIIS 130
>07310
          Length = 712

 Score =  126 bits (317), Expect = 2e-29,   Method: Compositional matrix adjust.
 Identities = 66/203 (32%), Positives = 117/203 (57%), Gaps = 1/203 (0%)
 Frame = +2

Query: 245 LVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLKDYIHINIGA 304
           LVLDEAD++L   F+  +  I+  + P RQ L++SAT+P  V Q  + +LK+   IN+  
Sbjct: 56  LVLDEADKLLSQDFKGMLDNIIAHLPPQRQILLYSATFPLSVEQFMKKYLKNPYEINLME 235

Query: 305 LELSANHNILQIVDVCHDVEKDEKLIRLMEEIMSEKE-NKTIVFVETKRRCDELTRKMRR 363
            EL+     L+ V   +   ++++ +  +  + S+ + N++I+F  + +R + L +K+  
Sbjct: 236 -ELT-----LKGVTQYYAFVQEKQKVHCLNTLFSKLQINQSIIFCNSTQRVELLAKKITE 397

Query: 364 DGWPAMGIHGDKSQQERDWVLNEFKHGKAPILIATDVASRGLDVEDVKFVINYDYPNSSE 423
            G+    IH   +QQ R+ V ++F+ G    L+ +D+ +RG+D++ V  VIN+D+P  +E
Sbjct: 398 LGYSCYYIHAKMNQQHRNRVFHDFRQGLCRNLVCSDLFTRGIDIQAVNVVINFDFPKHAE 577

Query: 424 DYIHRIGRTARSTKTGTAYTFFT 446
            Y+HRIGR+ R    G A    T
Sbjct: 578 TYLHRIGRSGRYGHLGVAINLIT 646
>00739
          Length = 1313

 Score =  126 bits (316), Expect = 3e-29,   Method: Compositional matrix adjust.
 Identities = 82/252 (32%), Positives = 135/252 (53%), Gaps = 3/252 (1%)
 Frame = +3

Query: 210 QIRDLERGVEICIATPGRLIDFLE-CGKTNLRRTTYLVLDEADRMLDMGFEPQIRKIVDQ 268
           Q +DL     I I+TPGRL D ++ C   +L+R  +LV+DEADR+LD  F  Q+  I+ +
Sbjct: 18  QGQDLAVKPHIVISTPGRLADHIDSCDTFSLKRVKFLVMDEADRLLDDNFGAQLEPILTR 197

Query: 269 IRPDRQTLMWSATWPKEVRQLAEDFL-KDYIHINIGALELSANHNILQIVDVCHDVEKDE 327
           +   RQTL++SAT    V  L +  L K ++ I     E +    + +   +     KD 
Sbjct: 198 LPSARQTLLFSATLSPTVNALRDSVLNKPFVWIQQS--ERATVDELQEDYVLVPASMKDA 371

Query: 328 KLIRLMEEIMSEK-ENKTIVFVETKRRCDELTRKMRRDGWPAMGIHGDKSQQERDWVLNE 386
            ++ +++  + +   +  I+F  T +    L   + +  +    +H    Q+ R   L+ 
Sbjct: 372 YMVHILDHWLKDHPRSSLIIFTXTCKYAQILGMMLEKLQFSCAVLHSMIPQRFRLSSLSR 551

Query: 387 FKHGKAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYIHRIGRTARSTKTGTAYTFFT 446
           FK  +  ILI+TDVASRGLD+  V  +IN++ PN   DY+HR+GRTAR+ + G + +  T
Sbjct: 552 FKSNQTRILISTDVASRGLDIPTVDLIINHNIPNRPRDYVHRVGRTARAGRCGQSISLVT 731

Query: 447 PNNIKQVSDLIS 458
             +IK +  + S
Sbjct: 732 EFDIKLIKSIES 767
>12121
          Length = 465

 Score =  121 bits (303), Expect = 1e-27,   Method: Compositional matrix adjust.
 Identities = 54/107 (50%), Positives = 73/107 (68%)
 Frame = -2

Query: 37  PGEKLVKKKWNLDELPKFEKNFYQEHPDLARRTAQEVDTYRRSKEITVRGHNCPKPVLNF 96
           PG  L K KW+L +L +FEK+FY+E P +A R   ++  +R + +IT+ G   P P+L F
Sbjct: 323 PGANLRKPKWDLSKLVRFEKHFYKEAPSVANRNPIQIQEFRNNNQITLSGRYLPNPILTF 144

Query: 97  YEANFPANVMDVIARQNFTEPTAIQAQGWPVALSGLDMVGVAQTGSG 143
            EAN P  VM  I R N+T PT IQ+Q WP+A+SG D+VG+AQTGSG
Sbjct: 143 EEANLPDYVMSQIHRNNWTSPTPIQSQSWPIAMSGKDLVGIAQTGSG 3

 Score = 82.0 bits (201), Expect = 6e-16,   Method: Composition-based stats.
 Identities = 45/87 (51%), Positives = 50/87 (57%), Gaps = 13/87 (14%)
 Frame = -3

Query: 220 ICIATPGRLIDFLECGKTNLRRTTYLVLDEADRMLDMGFEPQIRKIVDQ---IRPDRQTL 276
           ICIATPGRLIDFLE  +TNLRR TYLVLDEADRMLDMGF P  R    +     P   + 
Sbjct: 463 ICIATPGRLIDFLESNRTNLRRCTYLVLDEADRMLDMGFXPP*RACSLEPTCASPSGTSP 284

Query: 277 MWSA----------TWPKEVRQLAEDF 293
            WSA           WP E +   + F
Sbjct: 283 NWSALRNTSTKRLLVWPIETQYRYKSF 203
>02498
          Length = 1955

 Score = 70.9 bits (172), Expect(2) = 2e-26,   Method: Compositional matrix adjust.
 Identities = 44/156 (28%), Positives = 78/156 (50%), Gaps = 6/156 (3%)
 Frame = +3

Query: 325 KDEKLIRLMEEIMSEKENKTIVFVETKRRCDELTRKMRRDGWPAMGIHGDKSQQERDWVL 384
           ++EK + L     S    ++++F   +     L  +M  D      + G+ + ++R  ++
Sbjct: 810 QEEKYVALCNIYGSISVGQSMIFCHKRSTAAWLAERMTADHHAVGLLTGELTIEQRAAII 989

Query: 385 NEFKHGKAPILIATDVASRGLDVEDVKFVINYDYPNS------SEDYIHRIGRTARSTKT 438
             F+ GK  +LI T+V++RG+DVE V  V+N+D P +       E Y+HRIGRT R  K 
Sbjct: 990 KRFREGKEKVLITTNVSARGIDVEMVTVVVNFDLPVTQDWRPDCETYLHRIGRTGRFGKN 1169

Query: 439 GTAYTFFTPNNIKQVSDLISVLREANQAINPKLLQL 474
           G A       N+   S  ++++R   +    K+ +L
Sbjct: 1170GIAI------NMVDNSRSMAIMRSIEKHFGRKIEKL 1259

 Score = 67.4 bits (163), Expect(2) = 2e-26,   Method: Compositional matrix adjust.
 Identities = 62/230 (26%), Positives = 103/230 (44%), Gaps = 16/230 (6%)
 Frame = +1

Query: 81  EITVRGHNCPKPVLNFYEA-NFPANVMDVIARQNFTEPTAIQAQGWPVALSG--LDMVGV 137
           E+  +  N P   +  +EA N    ++  +    F  P+ IQ    P+ L+   ++M+  
Sbjct: 91  EVLRKDPNSPLYSVKSFEALNLKPQLLKGVYDMGFNAPSKIQETALPILLADPPVNMIAQ 270

Query: 138 AQTGSGKTLSYLLPAIVHIN-HQPFLERGDGPICLVLAPTRELXXXXXXXXXEYCRACRL 196
           +Q+G+GKT +++L  +  ++  Q F      P CL LAPT EL         +  +    
Sbjct: 271 SQSGTGKTAAFVLTMLSRVDISQTF------PQCLCLAPTYELALQIGEVIEKMSKHM-- 426

Query: 197 KSTCIYGGAPKGPQIRDLERG----------VEICIATPGRLIDFLECGKT-NLRRTTYL 245
                      G +IR   RG           +I I TPG ++D+    K   L +    
Sbjct: 427 ----------TGLEIRYAVRGERVNRGEVLSEQIVIGTPGTVMDWSHRFKALPLEKLRVF 576

Query: 246 VLDEADRMLDM-GFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFL 294
           VLDEAD M+ M G + Q  +I  ++    Q L++SAT+ + V Q A+  +
Sbjct: 577 VLDEADVMISMQGHQDQSTRIQKRLSSGCQMLLFSATYDQVVMQFAQRII 726
>33025
          Length = 558

 Score =  108 bits (270), Expect(2) = 4e-25,   Method: Compositional matrix adjust.
 Identities = 57/156 (36%), Positives = 94/156 (60%), Gaps = 4/156 (2%)
 Frame = +3

Query: 189 EYCRACRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLECGKTNLRRTTYLVLD 248
           ++ R   +  + +YG   +  Q   + +G  + + TPGRL+DF+     +L +  YL+LD
Sbjct: 21  KFSRGTDVHPSVVYGATDRRYQKSRIMKGANLVVGTPGRLLDFIGDQTISLGKCQYLILD 200

Query: 249 EADRMLDMGFEPQIRKIVDQI----RPDRQTLMWSATWPKEVRQLAEDFLKDYIHINIGA 304
           EADRMLDMGFEP+IRK+VD      +  RQTLM+SAT+ +++++LA DFL DY+ I +G 
Sbjct: 201 EADRMLDMGFEPEIRKLVDTHGMPPKTQRQTLMFSATFKEDIQRLAGDFLNDYLFITVGI 380

Query: 305 LELSANHNILQIVDVCHDVEKDEKLIRLMEEIMSEK 340
           +   A  ++ Q       ++K + L  ++ E+ + K
Sbjct: 381 VG-GACSDVTQTFLEVDRLQKRDHLCEILNEMGTAK 485

 Score = 25.0 bits (53), Expect(2) = 4e-25,   Method: Composition-based stats.
 Identities = 11/31 (35%), Positives = 16/31 (51%)
 Frame = +1

Query: 337 MSEKENKTIVFVETKRRCDELTRKMRRDGWP 367
           M   + K +VFV  KR  D L   + + G+P
Sbjct: 466 MRWAQQKVLVFVGQKRNADFLASYLSQSGYP 558
>14337
          Length = 693

 Score =  104 bits (259), Expect = 1e-22,   Method: Compositional matrix adjust.
 Identities = 48/131 (36%), Positives = 77/131 (58%)
 Frame = +2

Query: 344 TIVFVETKRRCDELTRKMRRDGWPAMGIHGDKSQQERDWVLNEFKHGKAPILIATDVASR 403
            +VFV++K+R  EL  +   D      IH DK Q ERD  +  F  G+  +L+ T++  R
Sbjct: 65  VLVFVQSKQRAKELYSEFMFDKHKVDAIHADKPQAERDATVRAFTEGRVWVLVCTELMGR 244

Query: 404 GLDVEDVKFVINYDYPNSSEDYIHRIGRTARSTKTGTAYTFFTPNNIKQVSDLISVLREA 463
           G+D + +  VINYD+P ++  YIHRIGRT R+   G A TFFT  ++  +  + ++++EA
Sbjct: 245 GIDFKGINLVINYDFPTNAVSYIHRIGRTGRAGVPGRAITFFTEQDVTHLRSIANIIKEA 424

Query: 464 NQAINPKLLQL 474
              +   +L+L
Sbjct: 425 GCEVPEYMLRL 457
>22006
          Length = 3414

 Score = 96.7 bits (239), Expect = 2e-20,   Method: Compositional matrix adjust.
 Identities = 53/140 (37%), Positives = 76/140 (54%)
 Frame = +2

Query: 117  PTAIQAQGWPVALSGLDMVGVAQTGSGKTLSYLLPAIVHINHQPFLERGDGPICLVLAPT 176
            PT IQ +  PV + G DMV +A+TGSGKT ++L+P +  +     +    G   L+L+PT
Sbjct: 3005 PTPIQRKTIPVIMEGKDMVAMARTGSGKTAAFLVPMLERLK----MHSSKGARALILSPT 3172

Query: 177  RELXXXXXXXXXEYCRACRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLECGK 236
            REL         E  +   L++  I GG     Q   L +  +I IATPGRL+  L   K
Sbjct: 3173 RELALQTLKFTKELGKFLDLRAAVILGGDRMEDQFSALHQNPDIIIATPGRLLHVLVEMK 3352

Query: 237  TNLRRTTYLVLDEADRMLDM 256
             +L+   Y+V DEADR+ +M
Sbjct: 3353 KSLKEVIYVVFDEADRLFEM 3412
>08036
          Length = 1226

 Score = 65.5 bits (158), Expect(2) = 3e-20,   Method: Compositional matrix adjust.
 Identities = 44/179 (24%), Positives = 88/179 (49%), Gaps = 1/179 (0%)
 Frame = +1

Query: 222 IATPGRLIDFLECGKTNLRRTTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSAT 281
           + TP R++  L  G   L     LV+DEAD +   G E  ++K+++++    Q  + SAT
Sbjct: 4   VGTPSRILAHLRAGHLELHTVQMLVVDEADLVFSFGHEADMKKLMEELPRIYQAFLMSAT 183

Query: 282 WPKEVRQLAEDFLKDYIHINIGALELSANHNILQIVDVCHDVEKDEKLIRLMEEI-MSEK 340
             ++V+ L +  L + + + +   +L  +  + Q    C   E D+K   ++  + +   
Sbjct: 184 LSEDVKALKKMVLHNPVILKLKESQLPESTQLTQYHVKC---EVDDKFTLMVAVLKLGLV 354

Query: 341 ENKTIVFVETKRRCDELTRKMRRDGWPAMGIHGDKSQQERDWVLNEFKHGKAPILIATD 399
             K+I+FV +   C +L   +   G PA  ++ +   + R  ++++F  G   I+IA+D
Sbjct: 355 RGKSILFVNSVDSCYKLKLFLEPFGIPACVLNSELPVKSRCHIVSQFNEGLYDIIIASD 531

 Score = 51.6 bits (122), Expect(2) = 3e-20,   Method: Compositional matrix adjust.
 Identities = 20/45 (44%), Positives = 32/45 (71%)
 Frame = +3

Query: 402 SRGLDVEDVKFVINYDYPNSSEDYIHRIGRTARSTKTGTAYTFFT 446
           +RG+D ++V  VIN+++P + + YIHR+GRTAR  K G A +  +
Sbjct: 612 ARGIDFQNVSNVINFEFPKTVDAYIHRVGRTARGDKQGCALSLIS 746
>34134
          Length = 271

 Score = 94.0 bits (232), Expect = 2e-19,   Method: Composition-based stats.
 Identities = 41/51 (80%), Positives = 46/51 (90%)
 Frame = +3

Query: 126 PVALSGLDMVGVAQTGSGKTLSYLLPAIVHINHQPFLERGDGPICLVLAPT 176
           P+A+SG D VG+AQTGSGKTLS++LPAIVHINHQP LERGDGPI LVL PT
Sbjct: 87  PIAMSGRDCVGIAQTGSGKTLSFILPAIVHINHQPTLERGDGPIALVLVPT 239
>19640
          Length = 456

 Score = 91.7 bits (226), Expect = 9e-19,   Method: Composition-based stats.
 Identities = 37/86 (43%), Positives = 61/86 (70%)
 Frame = -1

Query: 346 VFVETKRRCDELTRKMRRDGWPAMGIHGDKSQQERDWVLNEFKHGKAPILIATDVASRGL 405
           +F  T+R+ D+LT++M    +    +HGD  Q++R+ ++ +F+ G + +LI TD+ +RG+
Sbjct: 456 IFCNTRRKVDQLTQEMSSHNFTVSAMHGDMEQRDREVIMKQFRSGSSRVLITTDLLARGI 277

Query: 406 DVEDVKFVINYDYPNSSEDYIHRIGR 431
           DV+ V  VINYD P++ E+YIHRIGR
Sbjct: 276 DVQQVSLVINYDLPSNRENYIHRIGR 199
>12995
          Length = 1072

 Score = 89.0 bits (219), Expect = 5e-18,   Method: Compositional matrix adjust.
 Identities = 40/137 (29%), Positives = 79/137 (57%)
 Frame = +3

Query: 320 CHDVEKDEKLIRLMEEIMSEKENKTIVFVETKRRCDELTRKMRRDGWPAMGIHGDKSQQE 379
           C   +K+  L+ L+ +++SE +  T+VFV TK   + L   + + G     I+    Q  
Sbjct: 69  CRADDKEAMLLYLLRDVISEND-LTVVFVATKHHVEYLNTLLTKCGIACTYIYSSLDQTA 245

Query: 380 RDWVLNEFKHGKAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYIHRIGRTARSTKTG 439
           R   + +F H +  +++ TD+A+RG+D+  +  V+N+ +P  ++ ++HR+GR AR+ ++G
Sbjct: 246 RKIHVAKFTHKQVKVMLVTDLAARGIDIPQLDNVVNFHFPAKAKLFVHRVGRVARAGRSG 425

Query: 440 TAYTFFTPNNIKQVSDL 456
           TAY+    + +  + DL
Sbjct: 426 TAYSLVAMDEVAHLVDL 476
>34295
          Length = 694

 Score = 84.3 bits (207), Expect = 1e-16,   Method: Compositional matrix adjust.
 Identities = 41/102 (40%), Positives = 61/102 (59%)
 Frame = -1

Query: 344 TIVFVETKRRCDELTRKMRRDGWPAMGIHGDKSQQERDWVLNEFKHGKAPILIATDVASR 403
            ++F  TK+ C  L+  +       + +HG   Q+ER   L+ FK      LIATDVA+R
Sbjct: 535 VMIFTNTKKYCQLLSMTLTNMEIENVCLHGFMRQKERVSALSRFKSNHIRTLIATDVAAR 356

Query: 404 GLDVEDVKFVINYDYPNSSEDYIHRIGRTARSTKTGTAYTFF 445
           GLD+  V+ VIN+  P + ++YIHR+GRTAR+ + G A + F
Sbjct: 355 GLDIPSVQLVINHMLPRTPKEYIHRVGRTARAGRKGVAISIF 230
>17544
          Length = 1047

 Score = 79.3 bits (194), Expect = 4e-15,   Method: Compositional matrix adjust.
 Identities = 46/149 (30%), Positives = 70/149 (46%), Gaps = 12/149 (8%)
 Frame = +2

Query: 82  ITVRGHNCPKPVLNFYEANFPANVMDVIARQNFTEPTAIQAQGWPVALSGLDMVGVAQTG 141
           +   G + P  + +F E      + + I    + +PT +Q    P+ L   D++  AQTG
Sbjct: 596 VEATGDSPPPHINSFEECTLGEIIRNNIVLSKYNKPTPVQKFALPIVLGKRDLMACAQTG 775

Query: 142 SGKTLSYLLPAIVHI------------NHQPFLERGDGPICLVLAPTRELXXXXXXXXXE 189
           SGKT ++LLP +  +            N      R   PI L+LAPTREL         +
Sbjct: 776 SGKTAAFLLPILNQVYENGPTPEALQQNQSRGYRRKMYPIALILAPTRELASQIYDEARK 955

Query: 190 YCRACRLKSTCIYGGAPKGPQIRDLERGV 218
           +    RL+   +YGGA  G Q+RDL++G 
Sbjct: 956 FAYRSRLRPCVVYGGADIGAQMRDLDKGC 1042
>00617
          Length = 1505

 Score = 77.8 bits (190), Expect = 1e-14,   Method: Compositional matrix adjust.
 Identities = 37/88 (42%), Positives = 55/88 (62%)
 Frame = -3

Query: 371  IHGDKSQQERDWVLNEFKHGKAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYIHRIG 430
            +H    Q+ R   L+ FK  +  ILI+TDVASRGLD+  V  +IN++ PN   DY+HR+G
Sbjct: 1467 LHSMIPQRFRLSSLSRFKSNQTRILISTDVASRGLDIPTVDLIINHNIPNRPRDYVHRVG 1288

Query: 431  RTARSTKTGTAYTFFTPNNIKQVSDLIS 458
            RTAR+ + G + +  T  +IK +  + S
Sbjct: 1287 RTARAGRCGQSISLVTEFDIKLIKSIES 1204
>17708
          Length = 882

 Score = 77.0 bits (188), Expect = 2e-14,   Method: Compositional matrix adjust.
 Identities = 39/101 (38%), Positives = 62/101 (61%)
 Frame = +1

Query: 133 DMVGVAQTGSGKTLSYLLPAIVHINHQPFLERGDGPICLVLAPTRELXXXXXXXXXEYCR 192
           D++G A+TGSGKTL++L+PAI  +    F+ R +G  C++++PTREL         E  +
Sbjct: 556 DLMGAAKTGSGKTLAFLIPAIELMYKLKFMPR-NGTGCIIISPTRELSMQTFNVLTELLK 732

Query: 193 ACRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLE 233
                   I GG  +  +++ L++GV I +ATPGRL+D L+
Sbjct: 733 YHHHTFGLIMGGVNRHDEVKKLKKGVNIIVATPGRLLDHLQ 855
>19525
          Length = 585

 Score = 74.3 bits (181), Expect = 1e-13,   Method: Composition-based stats.
 Identities = 61/198 (30%), Positives = 95/198 (47%), Gaps = 17/198 (8%)
 Frame = +2

Query: 171 LVLAPTRELXXXXXXXXXEYCRACRLKSTCIYGGAPKGPQIRDLERGVEIC----IATPG 226
           LVL PTREL         +  +  ++ S C+  G   G  I+  E  + +C    +ATPG
Sbjct: 23  LVLVPTRELAVQVYQVGQQISQYTKI-SICLAAG---GLDIKGQEAALRLCPDIVVATPG 190

Query: 227 RLIDFLECGKT-NLRRTTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKE 285
           RLID L       +     LVLDEADRMLD  F  Q+ +I+      RQT+++SAT    
Sbjct: 191 RLIDHLHNAPNFTIAHVEILVLDEADRMLDEYFAAQMTEIIRMCNFQRQTMLFSATMSDA 370

Query: 286 VRQLAEDFLKDYIHINIGALELSANHNILQIVDVCHDVEKDEKLIRLMEEIMSEKE---- 341
           V+ LA   LK+       A+++  N N     D+   ++++   +R+ E    ++E    
Sbjct: 371 VQDLASVSLKE-------AVKVFVNQN----TDIALGLQQE--FVRIRENKEGDREAIVS 511

Query: 342 --------NKTIVFVETK 351
                   +K +VF++TK
Sbjct: 512 SLVSRTFCDKCMVFLQTK 565
>11624
          Length = 2257

 Score = 73.6 bits (179), Expect = 2e-13,   Method: Compositional matrix adjust.
 Identities = 36/97 (37%), Positives = 59/97 (60%)
 Frame = -1

Query: 378 QERDWVLNEFKHGKAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYIHRIGRTARSTK 437
           + R  +L +F  GK  +L+ +D  +RG+DV++VK+VI+YD P   + YIHR+GRTAR+ +
Sbjct: 790 ERRKKILKQFSKGKIDLLVCSDAMARGMDVDNVKYVISYDNPPYIKTYIHRVGRTARAGR 611

Query: 438 TGTAYTFFTPNNIKQVSDLISVLREANQAINPKLLQL 474
            GTA +       K+      ++REA +    K ++L
Sbjct: 610 AGTAISLLEK---KEFFHFKQMMREAGKWKKIKEMKL 509

 Score = 54.3 bits (129), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 40/135 (29%), Positives = 62/135 (45%), Gaps = 12/135 (8%)
 Frame = -3

Query: 133  DMVGVAQTGSGKTLSYLLPAIVHINHQ--PFLERGDGPICLVLAPTRELXXXXXXXXXEY 190
            D+   A TGSGKTL+Y LP I  +  +  P +        +++ P R+L          Y
Sbjct: 1811 DICVSAPTGSGKTLAYTLPIIQCLKQRMVPHVR------AVIVLPVRDLAEQVYQVFCHY 1650

Query: 191  CRACRLKSTCIYGGAPKGPQIRDLERG---------VEICIATPGRLIDFLECGKT-NLR 240
            C    LK   + G      +   L +          ++I +ATPGRL+D +      +L 
Sbjct: 1649 CADTPLKVGIVVGKTVFNVEQDTLVKKRYGGVYHSVIDILVATPGRLVDHINSTPGFDLS 1470

Query: 241  RTTYLVLDEADRMLD 255
               +LV+DEADRM++
Sbjct: 1469 HLRFLVIDEADRMME 1425
>39583
          Length = 234

 Score = 68.9 bits (167), Expect = 6e-12,   Method: Composition-based stats.
 Identities = 30/57 (52%), Positives = 43/57 (75%)
 Frame = -3

Query: 379 ERDWVLNEFKHGKAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYIHRIGRTARS 435
           +R   L  FK G+  +L+ATD+ASRGLD+E VK VIN+  P++ + Y+HR+GRTAR+
Sbjct: 175 QRLEALKRFKEGEIDVLLATDLASRGLDIEGVKTVINFTMPSTLKHYVHRVGRTARA 5
>11160
          Length = 646

 Score = 65.5 bits (158), Expect = 7e-11,   Method: Compositional matrix adjust.
 Identities = 55/184 (29%), Positives = 92/184 (50%), Gaps = 13/184 (7%)
 Frame = -1

Query: 214 LERGVEICIATPGRLIDFL---ECG---KTNLRRTTYLVLDEADRMLDMGFEPQIRKIVD 267
           ++ G  I IATPGRL D     E G     +++    LVLDEADR+LDMGFE  I  I+ 
Sbjct: 610 MKSGGSILIATPGRLDDLFSRKESGFNLAASVKALEVLVLDEADRLLDMGFEASINTILG 431

Query: 268 QIRPDRQTLMWSATWPKEVRQLAEDFLKDYIHINIGALELSANHNI---LQIVDVCHDVE 324
            +   R+T ++SAT   EV  L    L++ + + +   +L+   +      + +    VE
Sbjct: 430 HLPKLRRTGLFSATQTDEVENLIRAGLRNPLRVTVKEKKLAGEADQRTPSTLSNYYMIVE 251

Query: 325 KDEKLIRLMEEIMSEKENKTIVFVETKRRCDE----LTRKMRRDGWPAMGIHGDKSQQER 380
            +EK  +L++ + +   +K ++F  T    D     LT+ ++      + IH  K +Q+R
Sbjct: 250 AEEKFSQLVKFLKTHHRDKLLLFFSTCACVDYFSMCLTQLLKH--MQVLSIHS-KMKQKR 80

Query: 381 DWVL 384
           +  L
Sbjct: 79  NLCL 68
>10649
          Length = 472

 Score = 64.3 bits (155), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 35/87 (40%), Positives = 42/87 (48%)
 Frame = +1

Query: 362 RRDGWPAMGIHGDKSQQERDWVLNEFKHGKAPILIATDVASRGLDVEDVKFVINYDYPNS 421
           R  G   + +HG   Q  R  +  EF   +  ILI TD+A RGLD   V +VI  D P  
Sbjct: 55  RAAGMSVLVLHGGIPQLRRLDIYREFCRKQHVILITTDLACRGLDFPAVNWVIQLDCPVD 234

Query: 422 SEDYIHRIGRTARSTKTGTAYTFFTPN 448
              YIHR GRTAR    G A     P+
Sbjct: 235 VNTYIHRAGRTARFECNGQALLVLLPS 315
>03381
          Length = 1206

 Score = 54.7 bits (130), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 26/71 (36%), Positives = 39/71 (54%)
 Frame = +3

Query: 405 LDVEDVKFVINYDYPNSSEDYIHRIGRTARSTKTGTAYTFFTPNNIKQVSDLISVLREAN 464
           LD+  ++ V+NYD     + + HR+GRT R+ + G+AYT  T  + +    L+  L  AN
Sbjct: 3   LDIPHIRTVVNYDVARDIDTHTHRVGRTGRAGEKGSAYTLITDKDKEFAPLLVRNLEGAN 182

Query: 465 QAINPKLLQLV 475
           Q   P LL L 
Sbjct: 183 QTPPPALLDLA 215
>19151
          Length = 625

 Score = 53.9 bits (128), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 26/58 (44%), Positives = 34/58 (58%), Gaps = 6/58 (10%)
 Frame = -3

Query: 394 ILIATDVASRGLDVEDVKFVINYDYP------NSSEDYIHRIGRTARSTKTGTAYTFF 445
           +LI T+V SRG+D+E V  V+N+D P         E Y+HRIGRT R  K+G A    
Sbjct: 620 VLITTNVLSRGIDIEQVTIVVNFDLPIDLRGNADCETYLHRIGRTGRFGKSGIAINLI 447
>31220
          Length = 818

 Score = 52.4 bits (124), Expect = 5e-07,   Method: Compositional matrix adjust.
 Identities = 29/71 (40%), Positives = 40/71 (56%)
 Frame = +2

Query: 401 ASRGLDVEDVKFVINYDYPNSSEDYIHRIGRTARSTKTGTAYTFFTPNNIKQVSDLISVL 460
           ASRG+D + V  VIN+D+P     YIHR GRTAR   TG+  +F +   +K++       
Sbjct: 161 ASRGIDFQGVNNVINFDFPLDVTSYIHRAGRTARGNNTGSVLSFVS---VKELP------ 313

Query: 461 REANQAINPKL 471
              NQA+  KL
Sbjct: 314 --INQAVEEKL 340
>33083
          Length = 1931

 Score = 49.7 bits (117), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 21/49 (42%), Positives = 31/49 (63%), Gaps = 1/49 (2%)
 Frame = +1

Query: 403 RGLDVEDVKFVINYDYPNSSEDYIHRIGRTARST-KTGTAYTFFTPNNI 450
           RGLD+  V +++ YD P+ S++YIHR+GRTAR    +G A     P  +
Sbjct: 1   RGLDIPQVDWIVQYDPPDESKEYIHRVGRTARGEGSSGKALLLLQPEEL 147
>11423
          Length = 1434

 Score = 45.8 bits (107), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 24/64 (37%), Positives = 37/64 (57%)
 Frame = -2

Query: 411  KFVINYDYPNSSEDYIHRIGRTARSTKTGTAYTFFTPNNIKQVSDLISVLREANQAINPK 470
            K+VI+YD P   + YIHR+GRTAR+ + GTA +       K+      ++REA +    K
Sbjct: 1397 KYVISYDNPPYIKTYIHRVGRTARAGRAGTAISLLEK---KEFFHFKQMMREAGKWKKIK 1227

Query: 471  LLQL 474
             ++L
Sbjct: 1226 EMKL 1215
>06438
          Length = 989

 Score = 43.9 bits (102), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 22/53 (41%), Positives = 26/53 (49%)
 Frame = +1

Query: 396 IATDVASRGLDVEDVKFVINYDYPNSSEDYIHRIGRTARSTKTGTAYTFFTPN 448
           +   +A RGLD   V +VI  D P     YIHR GRTAR    G A     P+
Sbjct: 25  LTVTLACRGLDFPAVNWVIQLDCPVDVNTYIHRAGRTARFECNGQALLVLLPS 183
>31899
          Length = 453

 Score = 41.2 bits (95), Expect = 0.001,   Method: Composition-based stats.
 Identities = 24/75 (32%), Positives = 39/75 (52%)
 Frame = -1

Query: 105 VMDVIARQNFTEPTAIQAQGWPVALSGLDMVGVAQTGSGKTLSYLLPAIVHINHQPFLER 164
           V++ +    F  P+ IQ +  P+   GLD++  A++G+GKT  + + A+  I        
Sbjct: 312 VLNGLKNAGFERPSPIQLKAIPLGRCGLDLIVQAKSGTGKTCVFSVVALEGIE-----TT 148

Query: 165 GDGPICLVLAPTREL 179
                 LVLAPTRE+
Sbjct: 147 ARSTQVLVLAPTREI 103
>01821
          Length = 910

 Score = 37.7 bits (86), Expect = 0.014,   Method: Compositional matrix adjust.
 Identities = 19/59 (32%), Positives = 29/59 (49%)
 Frame = +1

Query: 395 LIATDVASRGLDVEDVKFVINYDYPNSSEDYIHRIGRTARSTKTGTAYTFFTPNNIKQV 453
           L++T V   GLD+ DV  ++ YD   S    + R+GRT R  + G      T    +Q+
Sbjct: 13  LVSTCVGEEGLDIGDVDLIVCYDAHKSPVRLVQRMGRTGRK-RQGRIVMLMTEGKEEQI 186
>22529
          Length = 312

 Score = 28.9 bits (63), Expect = 6.2,   Method: Composition-based stats.
 Identities = 14/39 (35%), Positives = 22/39 (56%)
 Frame = +3

Query: 239 LRRTTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLM 277
           +R    L+LDEA   LDM  E  ++  +D+ R  R T++
Sbjct: 6   VRNPKILLLDEATSALDMESEKTVQDALDKARQGRTTIV 122
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|9790221|ref|NP_062741.1| actin related protein 2/3
complex, subunit 1A [Mus musculus]
         (370 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

03044                                                                 440   e-124
20615                                                                 216   9e-57
06576                                                                  42   4e-04
31474                                                                  35   0.038
02948                                                                  34   0.074
27681                                                                  32   0.43 
19498                                                                  29   2.6  
04874                                                                  28   4.2  
31384                                                                  28   4.4  
01598                                                                  28   4.4  
34005                                                                  28   4.7  
34947                                                                  28   4.8  
16105                                                                  28   5.2  
30108                                                                  28   6.6  
28312                                                                  28   7.7  
>03044
          Length = 1952

 Score =  440 bits (1131), Expect = e-124,   Method: Compositional matrix adjust.
 Identities = 212/398 (53%), Positives = 273/398 (68%), Gaps = 32/398 (8%)
 Frame = -2

Query: 4    HQFLLEPITCHAWNRDRTQIALSPNNHEVHIYKKNGSQWTKAHELKEHNGHITGIDWAPK 63
            H F ++ +TCHA + DR  +ALS N+HEV IYKKNGS+W +   L EH   +TGIDWAPK
Sbjct: 1798 HSFGVKAVTCHAASGDRNGLALSLNDHEVKIYKKNGSKWQETDTLGEHGQRVTGIDWAPK 1619

Query: 64   SDRIVTCGADRNAYVWSQKDGIWKPTLVILRINRAATFVKWSPLENKFAVGSGARLISVC 123
            S+RIVTCGADRNAYVW+ +DG W+P LVILRINRAAT VKWSP ENKFAVGS ARLISV 
Sbjct: 1618 SNRIVTCGADRNAYVWTYQDGKWQPHLVILRINRAATCVKWSPEENKFAVGSSARLISVS 1439

Query: 124  YFESENDWWVSKHIKKPIRSTVLSLDWHPNNVLLAAGSCDFKCRVFSAYIKEVDEKPAST 183
            Y+E E+ WWVSKHIKKPIRSTV  LDWHPNN+L+AAGS DFK RVFS Y+KE + KP   
Sbjct: 1438 YYEEEHRWWVSKHIKKPIRSTVTCLDWHPNNILIAAGSTDFKARVFSGYVKETEAKPGPN 1259

Query: 184  PWGSKMPFGQLMSEFXXXXXXXXXXXXXFSASGNRLAWVSHDSTVSVADASKSVQVSTLR 243
             WGSKM F  LM+EF             FS SG ++AWV+HDS+VSV D++   ++  ++
Sbjct: 1258 SWGSKMTFAALMAEF-SNGGGGWVHAVSFSPSGEKIAWVAHDSSVSVGDSTMQNRLVVIK 1082

Query: 244  TEFLPLLSVSFVSENSVVAAGHDCCPMLFNYDD-RGCLTFVSKLDVPKQSIQRN------ 296
              FLP + +++VSENS+VAAG+DC PML  Y+  +G L+ VSKLD+P++           
Sbjct: 1081 DTFLPFMGITWVSENSMVAAGYDCNPMLLTYNSGQGSLSLVSKLDIPQEKAAGTIRQVSM 902

Query: 297  -------------------------MSAMERFRNMDKRATTEDRNTALETLHQNSITQVS 331
                                     ++AM RF+++DK+A++ D +T L+T HQN+ITQVS
Sbjct: 901  EAGGAQAENNGCEEEGDDEEEMEVILNAMNRFKDLDKKASSGDSSTELKTQHQNTITQVS 722

Query: 332  IYEVDKQDCRKFCTTGIDGAMTIWDFKTLESSIQGLRI 369
            +YE  K  CR+  T+G+DG + +WD  +LE SIQ L+I
Sbjct: 721  VYEGTKGQCRRISTSGVDGNIILWDLNSLERSIQALKI 608
>20615
          Length = 641

 Score =  216 bits (551), Expect = 9e-57,   Method: Compositional matrix adjust.
 Identities = 104/194 (53%), Positives = 137/194 (70%), Gaps = 1/194 (0%)
 Frame = +1

Query: 149 DWHPNNVLLAAGSCDFKCRVFSAYIKEVDEKPASTPWGSKMPFGQLMSEFXXXXXXXXXX 208
           DWHPNNVL+AAGS DFK RVFS Y+KEV+ KP+S  WG+KM F  LM+EF          
Sbjct: 1   DWHPNNVLIAAGSTDFKTRVFSGYVKEVESKPSSNSWGAKMTFSNLMAEF-SNGGGGWVH 177

Query: 209 XXXFSASGNRLAWVSHDSTVSVADASKSVQVSTLRTEFLPLLSVSFVSENSVVAAGHDCC 268
              FS SG R+AWV HDS+VSVAD++   ++  ++  FLP + V++VSENS+VAAG DC 
Sbjct: 178 SVSFSPSGERIAWVGHDSSVSVADSANENRLVVIKDTFLPFMGVTWVSENSMVAAGFDCN 357

Query: 269 PMLFNYD-DRGCLTFVSKLDVPKQSIQRNMSAMERFRNMDKRATTEDRNTALETLHQNSI 327
           P LF YD  +G ++ VSKLD+P+Q     +SAM  FRNMDK A++ +++T L+T HQN+I
Sbjct: 358 PTLFTYDAGKGSVSLVSKLDIPQQKETGTVSAMSHFRNMDKNASSGEKSTELKTQHQNTI 537

Query: 328 TQVSIYEVDKQDCR 341
           TQVS+YE  K  C+
Sbjct: 538 TQVSVYEGTKDKCK 579
>06576
          Length = 1547

 Score = 42.0 bits (97), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 40/170 (23%), Positives = 68/170 (40%), Gaps = 18/170 (10%)
 Frame = -2

Query: 9    EPITCHAWNRDRTQ--------IALSPNNHEVHIYKKNGSQWTKAHELKEHNGHITGIDW 60
            + ++C AW+   +          A + ++H V ++  +     K H +K H   +  + +
Sbjct: 1237 QGVSCLAWSPSTSLSSLDKHLCFAAACDDHSVRVFTSDLKTTNKTHVVKGHTDFVNSVTF 1058

Query: 61   AP-KSDRIVTCGADRNAYVWSQKDGI--WKPTLVILRINRAATFVKWSPLEN-KFAVGSG 116
            +P + D++ + G D    VW+ KDG        VI R+      V W   E  K  VG  
Sbjct: 1057 SPTEEDQVXSTGDDLTCRVWTGKDGQDGRYGESVIFRLTAPGMAVCWHADEPLKLMVGQK 878

Query: 117  ARLISVCYFESENDWWVSKHIKKPIRST------VLSLDWHPNNVLLAAG 160
              +I   +F   N        ++PI S       +L  DW  +N LL   
Sbjct: 877  DGIIR--FFSLSN--------QQPIMSLSCGVSPLLDCDWSKHNCLLVGA 758
>31474
          Length = 403

 Score = 35.4 bits (80), Expect = 0.038,   Method: Compositional matrix adjust.
 Identities = 20/73 (27%), Positives = 33/73 (45%), Gaps = 1/73 (1%)
 Frame = -3

Query: 13  CHAWNRDRTQIALSPNNHEVHIYKKNGSQWTKAHELKE-HNGHITGIDWAPKSDRIVTCG 71
           C AWN   T +A   ++  + I+ K G  W     L + H   +  + W+P  + + +  
Sbjct: 290 CVAWNPTGTLLASCGSDKIIKIWGKEGDNWVCKSTLTDAHTRTVRSLGWSPCGNYLSSAS 111

Query: 72  ADRNAYVWSQKDG 84
            D    VWS+K G
Sbjct: 110 FDATTAVWSRKGG 72

 Score = 32.7 bits (73), Expect = 0.25,   Method: Compositional matrix adjust.
 Identities = 19/70 (27%), Positives = 30/70 (42%), Gaps = 2/70 (2%)
 Frame = -3

Query: 48  LKEHNGHITGIDWAPKSDRIVTCGADRNAYVWSQKDGIW--KPTLVILRINRAATFVKWS 105
           L  H+ H   + W P    + +CG+D+   +W ++   W  K TL      R    + WS
Sbjct: 317 LSAHDEHAWCVAWNPTGTLLASCGSDKIIKIWGKEGDNWVCKSTLTDAH-TRTVRSLGWS 141

Query: 106 PLENKFAVGS 115
           P  N  +  S
Sbjct: 140 PCGNYLSSAS 111
>02948
          Length = 1207

 Score = 34.3 bits (77), Expect = 0.074,   Method: Compositional matrix adjust.
 Identities = 16/59 (27%), Positives = 31/59 (52%), Gaps = 8/59 (13%)
 Frame = -2

Query: 51   HNGHITGIDWAPKSD-RIVTCGADRNAYVWSQKDGI-------WKPTLVILRINRAATF 101
            H G +TG+   P +  ++++CG D N  VW+  DG+       + P   ++ ++ + TF
Sbjct: 1200 HRGQVTGLALNPANKLQLLSCGLDGNINVWAYVDGVLLRSYSHYMPLHALVSVDXSGTF 1024
>27681
          Length = 465

 Score = 32.0 bits (71), Expect = 0.43,   Method: Compositional matrix adjust.
 Identities = 25/76 (32%), Positives = 34/76 (44%), Gaps = 10/76 (13%)
 Frame = +2

Query: 104 WSPLENKFAVGSGARLISVCYFESEN----DWWVSKH-IKK-----PIRSTVLSLDWHPN 153
           W+P  +  A GSG     +    SE     +  V +H I+K     P    V SLDW+  
Sbjct: 17  WNPTNDLLASGSGDSTARIWNMTSETPNNANQLVLRHCIQKGGTEVPSNKDVTSLDWNSE 196

Query: 154 NVLLAAGSCDFKCRVF 169
             LLA GS D   R++
Sbjct: 197 GTLLATGSYDGYARLW 244
>19498
          Length = 903

 Score = 29.3 bits (64), Expect = 2.6,   Method: Compositional matrix adjust.
 Identities = 25/120 (20%), Positives = 47/120 (39%), Gaps = 6/120 (5%)
 Frame = -1

Query: 41  QWTKAHELKEHNGHITGIDWAPKSDRIVTCGADRNAYVWSQKDGIWKPTLVILRINRAAT 100
            W     L+ H G +  + W+P+   + +C  D    VW+     +   + ++R +    
Sbjct: 642 HWRSVATLRGHAGDVLDLAWSPQDLWLASCSVDNTIVVWNALK--FSEQVAVIRGHAGMV 469

Query: 101 -FVKWSPLENKFAVGSGARLISVCYFESENDWWVSKHIKKPIR-----STVLSLDWHPNN 154
             V W P+    A  S  + + V      +DW     +K   +     + VL L+W P+ 
Sbjct: 468 KGVTWDPVGRYLASQSDDKTLRV---WRTSDWKEETCVKSCFKECGGTTHVLRLNWSPDG 298
>04874
          Length = 1991

 Score = 28.5 bits (62), Expect = 4.2,   Method: Compositional matrix adjust.
 Identities = 14/29 (48%), Positives = 20/29 (68%), Gaps = 1/29 (3%)
 Frame = -3

Query: 107 LENKFAVGSGARLISVCYFE-SENDWWVS 134
           L+ K+A+    R ISVC F+ S +DW+VS
Sbjct: 669 LDPKYAMSFICREISVCLFKSSHDDWYVS 583
>31384
          Length = 474

 Score = 28.5 bits (62), Expect = 4.4,   Method: Compositional matrix adjust.
 Identities = 12/51 (23%), Positives = 24/51 (47%)
 Frame = -1

Query: 29  NHEVHIYKKNGSQWTKAHELKEHNGHITGIDWAPKSDRIVTCGADRNAYVW 79
           +++V  ++   S  T     + H G +  +DW+    ++ T   D+ A VW
Sbjct: 204 DNKVSCWEVQQSGQTIPKAQQTHTGPVLDVDWSDDGTKVFTASCDKTAKVW 52
>01598
          Length = 1545

 Score = 28.5 bits (62), Expect = 4.4,   Method: Compositional matrix adjust.
 Identities = 25/111 (22%), Positives = 47/111 (42%), Gaps = 2/111 (1%)
 Frame = +1

Query: 61  APKSDRIVTCGADRNAYVWSQKDGIWKPTLVILRINRAATFVKWSPLE-NKFAVGSGARL 119
            P S  + T   DR   +W  +    +    +  +      V+ SP++  + AVG G  +
Sbjct: 406 GPDSKTLCTFAQDRQVVLWDLE--TMEAVASMATLGGHVYCVRTSPIDPGRVAVGVGDSM 579

Query: 120 ISVCYFESENDWWVSKHIKKPIRSTVLSLDWHPN-NVLLAAGSCDFKCRVF 169
           I      ++ + +    + + I+S V ++ WHP     L  G+ D +  VF
Sbjct: 580 IRTWNMSNKTNPYDVTTLWQGIKSKVTAVAWHPTKEGWLGFGTDDGRIGVF 732
>34005
          Length = 456

 Score = 28.5 bits (62), Expect = 4.7,   Method: Compositional matrix adjust.
 Identities = 17/64 (26%), Positives = 30/64 (46%), Gaps = 2/64 (3%)
 Frame = +1

Query: 55  ITGIDWAPKSDRIVTCGADRNAYVWSQKDGIWKPTLVILRINRAAT-FVKWSPLENK-FA 112
           + G+ W+P +  + +   D +  +W    G+  P L  L  ++AA   V W P + +  A
Sbjct: 121 VCGLSWSPDATFLASGSNDNSVNIWDSTLGMDVPPLHTLTSHQAAVKAVAWCPWQTRMLA 300

Query: 113 VGSG 116
            G G
Sbjct: 301 TGGG 312
>34947
          Length = 197

 Score = 28.5 bits (62), Expect = 4.8,   Method: Composition-based stats.
 Identities = 14/32 (43%), Positives = 17/32 (53%), Gaps = 1/32 (3%)
 Frame = +3

Query: 3  LHQFLLEPITCHAWNRDRTQIALSPNN-HEVH 33
          LH  L  P   H W +DRT   L+P N H +H
Sbjct: 36 LHCRLRHPFA*HTWGQDRTVNILNPANIHNIH 131
>16105
          Length = 960

 Score = 28.5 bits (62), Expect = 5.2,   Method: Compositional matrix adjust.
 Identities = 16/73 (21%), Positives = 28/73 (38%), Gaps = 6/73 (8%)
 Frame = -2

Query: 51  HNGHITGIDWAPKSDRIVTCGADR-NAYVWSQKD-----GIWKPTLVILRINRAATFVKW 104
           H G +  I W P +D ++   +D     VW   D      +  P + ++   +    + W
Sbjct: 578 HKGAVLDIQWCPHNDNVIASASDDCTVKVWQIPDSGLVTNLTDPVVDLVGHQKRCCLIVW 399

Query: 105 SPLENKFAVGSGA 117
            P      V +GA
Sbjct: 398 HPSAQNVLVSAGA 360
>30108
          Length = 1032

 Score = 28.1 bits (61), Expect = 6.6,   Method: Compositional matrix adjust.
 Identities = 16/71 (22%), Positives = 31/71 (43%), Gaps = 1/71 (1%)
 Frame = +1

Query: 10  PITCHAWNRDRTQIALSPNNHEVHI-YKKNGSQWTKAHELKEHNGHITGIDWAPKSDRIV 68
           P+   AW+   T+ AL+  ++ VH+ Y  +       H+L++   H+    W P S  ++
Sbjct: 106 PVRAFAWHPHTTKFALALQDNSVHVHYSASTLVPVLKHKLQKSVAHLA---WQPLSASVL 276

Query: 69  TCGADRNAYVW 79
                    +W
Sbjct: 277 AVACQSAVLIW 309
>28312
          Length = 698

 Score = 27.7 bits (60), Expect = 7.7,   Method: Compositional matrix adjust.
 Identities = 20/80 (25%), Positives = 32/80 (40%), Gaps = 2/80 (2%)
 Frame = +2

Query: 16  WNRDRTQIAL-SPNNHEVHIYKKNGSQWTKAHELKEHNGHITGIDWAPKSDRIVTCGADR 74
           WN   T+    +P + ++HI  K     ++ + LK   G     DW    +    C  DR
Sbjct: 62  WNLKETRFCFWTPRSEKIHILSKMCGTLSECNHLKRSVGLDCMRDWYRNWECYECCQGDR 241

Query: 75  -NAYVWSQKDGIWKPTLVIL 93
            N YV     G+     ++L
Sbjct: 242 CNFYVTLGASGVTSSVTLLL 301
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|126723461|ref|NP_033970.3| chaperonin subunit 8
(theta) [Mus musculus]
         (548 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

05356                                                                 439   e-123
01159                                                                 194   8e-50
06409                                                                 144   9e-35
12796                                                                 129   4e-30
29631                                                                  75   8e-29
09900                                                                 107   1e-23
29864                                                                  72   6e-13
02673                                                                  68   1e-11
33770                                                                  60   3e-09
34332                                                                  56   3e-08
30661                                                                  54   1e-07
15785                                                                  47   2e-05
>05356
          Length = 2339

 Score =  439 bits (1128), Expect = e-123,   Method: Compositional matrix adjust.
 Identities = 206/300 (68%), Positives = 246/300 (82%)
 Frame = +2

Query: 1   MALHVPKAPGFAQMLKDGAKHFSGLEEAVYRNIQACKELAQTTRTAYGPNGMNKMVINRL 60
           MA+HVP+APGFAQMLKDGAKHFSGL+EAVYRNI+ACKELA+TTR+AYGP+G NKMVIN L
Sbjct: 191 MAMHVPRAPGFAQMLKDGAKHFSGLDEAVYRNIEACKELAKTTRSAYGPHGQNKMVINHL 370

Query: 61  EKLFVTNDAATILRELEVQHPAAKMIVMASHMQEQEVGDGTNFVLVFXXXXXXXXXXXXR 120
           EKLFVTNDAATILRELEVQHPAAKM+V+A+H QEQE GDGTNFVLVF            R
Sbjct: 371 EKLFVTNDAATILRELEVQHPAAKMLVLAAHQQEQECGDGTNFVLVFAGALLENAEQLLR 550

Query: 121 IGLSVSEVISGYEIACKKAHEILPELVCCSAKNLRDVDEVSSLLRTSIMSKQYGSETFLA 180
           +GLSV+EVI GYE+A KKAHEILP+LV    KNLR+ +EV + +RTS+MSKQYG+E FLA
Sbjct: 551 MGLSVTEVIEGYELALKKAHEILPKLVIGHVKNLRNKEEVKTAIRTSVMSKQYGNEDFLA 730

Query: 181 KLIAQACVSIFPDSGNFNVDNIRVCKILGSGIYSSSVLHGMVFKKETEGDVTSVKDAKIA 240
            LI  ACVS+ P   +F+VDN+RVCKILG G+  SS + GMVFK++ EG++T V+ AK+A
Sbjct: 731 DLITDACVSVLPAKISFSVDNVRVCKILGCGLLQSSTIQGMVFKRQVEGEITKVEKAKVA 910

Query: 241 VYSCPFDGMITETKGTVLIKTAEELMNFSKGEENLMDAQVKAIAGTGANVIVTGGKVADI 300
           V++CP D M TETKGTVLIK AEELM+FSKGEE++M+ Q+K I   G NVIV GGK A +
Sbjct: 911 VFTCPLDSMQTETKGTVLIKNAEELMSFSKGEEDMMEEQIKGIKEAGVNVIVAGGKSAXL 1090

 Score =  330 bits (845), Expect = 1e-90,   Method: Compositional matrix adjust.
 Identities = 150/243 (61%), Positives = 195/243 (80%)
 Frame = +1

Query: 285  GTGANVIVTGGKVADIALHYANKYNIMLVRLNSKWDLRRLCKTVGATALPKLTPPVQEEM 344
            G+      + G+V D+A HY NKY +M++RL SKWDLRRLCK++ ATALPK+T P  EE 
Sbjct: 1042 GSWRQCDCSWGEVGDLAQHYCNKYKVMVIRLLSKWDLRRLCKSICATALPKVTTPRNEEC 1221

Query: 345  GHCDSVYLSEVGDTQVVVFKHEKEDGAISTIVLRGSTDNLMDDIERAVDDGVNTFKVLTR 404
            G+CD VY+ E+G+T VV+F+  K++  I+T+++RGSTDN+MDDIERA+DDGVNTFK LT+
Sbjct: 1222 GYCDLVYVDEIGETPVVIFQQNKDESPITTVIIRGSTDNIMDDIERALDDGVNTFKALTK 1401

Query: 405  DKRLVPGGGATEIELAKQITSYGETCPGLEQYAIKKFAEAFEAIPRALAENSGVKANEVI 464
            D RLVPG GATEIELAKQIT+YGE+ PGLEQYA+KKFAE+ E IPRALAEN+G+KA +++
Sbjct: 1402 DDRLVPGAGATEIELAKQITTYGESLPGLEQYAVKKFAESLEVIPRALAENTGMKATDIL 1581

Query: 465  SKLYSVHQEGNKNVGLDIEAEVPAVKDMLEASILDTYLGKYWAIKLATNAAVTVLRVDQI 524
            SKLY+ HQEG +N G+DI+ +  +V D  +A++ D YL +YW +K A  AA TVLRVDQI
Sbjct: 1582 SKLYAAHQEGQQNAGVDID-DSGSVLDAKQANLTDLYLNRYWGLKFAAAAACTVLRVDQI 1758

Query: 525  IMA 527
            IMA
Sbjct: 1759 IMA 1767
>01159
          Length = 2613

 Score =  194 bits (493), Expect = 8e-50,   Method: Compositional matrix adjust.
 Identities = 151/516 (29%), Positives = 258/516 (50%), Gaps = 7/516 (1%)
 Frame = +3

Query: 16  KDGAKHFSGLEEAVYRNIQACKELAQTTRTAYGPNGMNKMVINRLEKLFVTNDAATILRE 75
           +D     +G+E A   +I A K +A   +T+ GP G++KM+++    + VTND ATIL  
Sbjct: 156 QDKKSRLTGIE-AHKSHILAAKSVASILKTSLGPKGLDKMMVSGDGDVTVTNDGATILDM 332

Query: 76  LEVQHPAAKMIVMASHMQEQEVGDGTNFVLVFXXXXXXXXXXXXRIGLSVSEVISGYEIA 135
           ++V H  AK++V  S  Q+ E+GDGT  V+V               G+    +  GYEIA
Sbjct: 333 MDVDHQIAKLMVQLSKSQDDEIGDGTTGVVVLAGALLEQAEKLLDRGIHPIRIADGYEIA 512

Query: 136 CKKAHEILPELVCCSAKNLRDVDEVSSLLRTSIMSKQYGS-ETFLAKLIAQACVSIFPDS 194
            K A E L ++      +L++ + +  L  T++ SK        +AK+   A +S+  D 
Sbjct: 513 AKCAVETLDKISDNYEVDLKNAEPLIKLAMTTLGSKIVNRCHRQMAKIAVDAIMSV-ADL 689

Query: 195 GNFNVDN--IRVCKILGSGIYSSSVLHGMVFKKETEGDVTS--VKDAKIAVYSCPFDGMI 250
              +VD   I+V   +G  +  + ++ G+V  K+         VKDAKIA+ +CPF+   
Sbjct: 690 KRKDVDFELIKVEGKVGGKLEDTMLVKGVVVDKDMSHPQMPKVVKDAKIAILTCPFEPPK 869

Query: 251 TETKGTVLIKTAEELMNFSKGEENLMDAQVKAIAGTGANVIVTGGKVADIALHYANKYNI 310
            +TK  + I + E+     + E N  ++ V+++   GAN+++      D A H   +  +
Sbjct: 870 PKTKHKLDITSVEDYKKLREYELNKFESMVQSVKDKGANLVICQWGFDDEANHLLLQREL 1049

Query: 311 MLVRLNSKWDLRRLCKTVGATALPKLTPPVQEEMGHCDSVYLSEVGDT--QVVVFKHEKE 368
             VR     ++  +    G   +P+      E++G    V     G T  +++V +    
Sbjct: 1050PAVRWVGGPEIELIAIATGGRIVPRFEELTTEKLGKAGIVRELTFGTTKDRMLVIEECLN 1229

Query: 369 DGAISTIVLRGSTDNLMDDIERAVDDGVNTFKVLTRDKRLVPGGGATEIELAKQITSYGE 428
             A+ TI +RG    ++++ +R++ D +   + L RD R+V GGGA EI  +  +    +
Sbjct: 1230TRAV-TIFIRGGNKMIVEEAKRSLHDALCVIRNLVRDNRVVYGGGAPEIAASVAVAEAAD 1406

Query: 429 TCPGLEQYAIKKFAEAFEAIPRALAENSGVKANEVISKLYSVHQEGNKNVGLDIEAEVPA 488
               LEQYA++ F+EA EA+P ALAENSG+   + ++++ S  Q   KN  L I+  +  
Sbjct: 1407KISTLEQYAVRSFSEALEAVPLALAENSGLAPIQTLAEVKS-RQVKEKNPRLGIDCLLKG 1583

Query: 489 VKDMLEASILDTYLGKYWAIKLATNAAVTVLRVDQI 524
             DM E ++++T   K   I LAT     +L++D I
Sbjct: 1584TNDMKEQNVIETLTAKKQQILLATQLVRMILKIDDI 1691
>06409
          Length = 1533

 Score =  144 bits (363), Expect = 9e-35,   Method: Compositional matrix adjust.
 Identities = 85/302 (28%), Positives = 156/302 (51%), Gaps = 5/302 (1%)
 Frame = -3

Query: 229  GDVTSVKDAKIAVYSCPFDGMITETKGTVLIKTAEELMNFSKGEENLMDAQVKAIAGTGA 288
            G  + V+ AKI           T+ +  V++    ++    + E N +   VK I   G 
Sbjct: 1507 GGPSKVEKAKIGFIQFCISPPKTDMENQVIVSDYTQMDRVLREERNYILDIVKKIKKAGC 1328

Query: 289  NVI-----VTGGKVADIALHYANKYNIMLVRLNSKWDLRRLCKTVGATALPKLTPPVQEE 343
            NV+     +    V+D+ALH+  K  IM+V+   + D+  +CKT+G   +  L   + E 
Sbjct: 1327 NVLLIQKSILRDAVSDLALHFLAKMKIMVVKDIEREDVEFVCKTLGCRPVASLDHFLPEN 1148

Query: 344  MGHCDSVYLSEVGDTQVVVFKHEKEDGAISTIVLRGSTDNLMDDIERAVDDGVNTFKVLT 403
            +G  D +   + G +++V        G   T+++RGS   ++++ +R++ D +   + L 
Sbjct: 1147 LGSADLIEEVQTGSSKIVKATGIANPGQTVTVLIRGSNKLVLEEADRSLHDALCVIRCLV 968

Query: 404  RDKRLVPGGGATEIELAKQITSYGETCPGLEQYAIKKFAEAFEAIPRALAENSGVKANEV 463
            + K L+ GGGA E E++ ++ +Y  T  G+EQY  + FAEA E IP  LAEN+G+     
Sbjct: 967  KKKALIAGGGAPETEMSMRLAAYANTLAGMEQYCFRAFAEALEVIPFTLAENAGLNPIST 788

Query: 464  ISKLYSVHQEGNKNVGLDIEAEVPAVKDMLEASILDTYLGKYWAIKLATNAAVTVLRVDQ 523
            ++ L + H +G +  G+++     A+ ++LE ++L   L    AI LA+    ++L++D 
Sbjct: 787  VTXLRTRHAQGERTAGINVRK--GAITNILEENVLQPLLVSTSAITLASETVRSILKIDD 614

Query: 524  II 525
            I+
Sbjct: 613  IV 608
>12796
          Length = 1316

 Score =  129 bits (323), Expect = 4e-30,   Method: Compositional matrix adjust.
 Identities = 88/337 (26%), Positives = 166/337 (49%), Gaps = 7/337 (2%)
 Frame = -3

Query: 196  NFNVDNIRVCKILGSGIYSSSVLHGMVFKKETEGD--VTSVKDAKIAVYSCPFDGMITET 253
            + ++ NI+V + LG  +  + +++G+VF   + G      ++ AKI +         T+ 
Sbjct: 1311 SVDLKNIKVIRSLGGTVEDTELVNGLVFTSRSAGTNAPKRIEKAKIGLIQFCISAPKTDM 1132

Query: 254  KGTVLIKTAEELMNFSKGEENLMDAQVKAIAGTGANVI-----VTGGKVADIALHYANKY 308
               V++     +    K E + +   VK I   G NV+     +    V+D+A H+ +K 
Sbjct: 1131 DHNVIVSDYAAMDRVLKEERSYILNIVKQIKKAGCNVLLVQKSILRDAVSDLAQHFLDKI 952

Query: 309  NIMLVRLNSKWDLRRLCKTVGATALPKLTPPVQEEMGHCDSVYLSEVGDTQVVVFKHEKE 368
              ++V+   + D+  +CKT+    +  L     E M   D V     G  + V     + 
Sbjct: 951  KCLVVKDVEREDIEFVCKTLHCRPIASLDHFTAENMSSADLVEEVASGTNKFVKITGIQN 772

Query: 369  DGAISTIVLRGSTDNLMDDIERAVDDGVNTFKVLTRDKRLVPGGGATEIELAKQITSYGE 428
             G   +I+ RGS   ++++  R++ D +   + L R++  + GGGA EIE+A Q+ +  +
Sbjct: 771  QGRTVSIICRGSNKLVLEEAARSLHDALCVVRCLVRNRAQIVGGGAPEIEMALQLAAAAQ 592

Query: 429  TCPGLEQYAIKKFAEAFEAIPRALAENSGVKANEVISKLYSVHQEGNKNVGLDIEAEVPA 488
            T  G++ Y  + FA+A E IP  LAEN+G+     +++L + H +G KN G+++     A
Sbjct: 591  TVDGVDAYCYRAFADALEVIPSTLAENAGLNPIATVTELRNRHAQGEKNAGINVRK--GA 418

Query: 489  VKDMLEASILDTYLGKYWAIKLATNAAVTVLRVDQII 525
            + D+   +++   L    AI LAT    ++L++D I+
Sbjct: 417  ITDIFAENVVQPLLVSTSAITLATETVRSILKIDDIV 307
>29631
          Length = 1257

 Score = 74.7 bits (182), Expect(3) = 8e-29,   Method: Compositional matrix adjust.
 Identities = 39/117 (33%), Positives = 61/117 (52%)
 Frame = +3

Query: 32  NIQACKELAQTTRTAYGPNGMNKMVINRLEKLFVTNDAATILRELEVQHPAAKMIVMASH 91
           NI A K +A   RT  GP  M KM+++ +  + +TND   ILRE+ VQHPAAK ++  + 
Sbjct: 60  NIAAGKTIADVIRTCLGPKSMLKMLMDPMGGIVMTNDGNAILREINVQHPAAKSMIEVAR 239

Query: 92  MQEQEVGDGTNFVLVFXXXXXXXXXXXXRIGLSVSEVISGYEIACKKAHEILPELVC 148
            Q++E GDGT  V++                +  + +I+ Y  A +   E+L   +C
Sbjct: 240 TQDEETGDGTKSVIILAGEVLSVAEQFLEQQMHPTVIIAAYRQALEDTLEVLRTKIC 410

 Score = 46.6 bits (109), Expect(3) = 8e-29,   Method: Compositional matrix adjust.
 Identities = 23/71 (32%), Positives = 41/71 (57%)
 Frame = +3

Query: 354  EVGDTQVVVFKHEKEDGAISTIVLRGSTDNLMDDIERAVDDGVNTFKVLTRDKRLVPGGG 413
            ++GD         K   A  TI+LRG++ +++ ++ER + D +N  + +  D  L PGGG
Sbjct: 1047 KIGDDYFTFLVDCKSPKA-CTILLRGASKDILAEVERNLQDAMNVARNVMIDPHLCPGGG 1223

Query: 414  ATEIELAKQIT 424
            A+E+ LA+ + 
Sbjct: 1224 ASEMALAQALN 1256

 Score = 44.3 bits (103), Expect(3) = 8e-29,   Method: Compositional matrix adjust.
 Identities = 42/181 (23%), Positives = 78/181 (43%), Gaps = 13/181 (7%)
 Frame = +1

Query: 178 FLAKLIAQAC-------VSIF-PDSGNFNVDNIR---VCKILGSGIYSSSVLHGMVFKKE 226
           F++K +  AC        ++F  ++G   +D  R   V KI G  +  S VL G+   K+
Sbjct: 478 FISKWMDLACQIALDATTTVFMEENGRKEIDIKRYAKVEKIPGGTMEESEVLKGIXVNKD 657

Query: 227 T--EGDVTSVKDAKIAVYSCPFDGMITETKGTVLIKTAEELMNFSKGEENLMDAQVKAIA 284
                    +++ +I +  C  +    E+   + I   E+     + EE  +      I 
Sbjct: 658 VVHXKMKRRIENPRIMLLDCNLEYKKGESATNIEISKEEDFAKILQLEEEYIRKMCDEII 837

Query: 285 GTGANVIVTGGKVADIALHYANKYNIMLVRLNSKWDLRRLCKTVGATALPKLTPPVQEEM 344
               ++++T   V+D+A H+  K  I ++R   K D  R+ +  GAT   +     +E+M
Sbjct: 838 ALKPDLVITEKGVSDLAQHFLLKAGISVLRRVRKTDNNRIARACGATIANRTDELKEEDM 1017

Query: 345 G 345
           G
Sbjct: 1018G 1020
>09900
          Length = 1305

 Score =  107 bits (267), Expect = 1e-23,   Method: Compositional matrix adjust.
 Identities = 73/272 (26%), Positives = 130/272 (47%), Gaps = 3/272 (1%)
 Frame = +3

Query: 257 VLIKTAEELMNFSKGEENLMDAQVKAIAGTGANVIVTGGKVADIALHYANKYNIMLVRLN 316
           V +   +E  +    E  ++  ++  I  +GA V+++   + D+A  Y    ++      
Sbjct: 117 VRVDNVQEYQSIVDAEWKILYDKLDKIHQSGAKVVLSKLPIGDVATQYFADRDMFCAGRV 296

Query: 317 SKWDLRRLCKTVGA---TALPKLTPPVQEEMGHCDSVYLSEVGDTQVVVFKHEKEDGAIS 373
            + DLRR  K  G    T +  LTP V   +G C      ++G  +  +FK         
Sbjct: 297 PEEDLRRTMKACGGSIQTTVQSLTPDV---LGTCQLFDEIQIGGERFNMFKGCTM-ARTC 464

Query: 374 TIVLRGSTDNLMDDIERAVDDGVNTFKVLTRDKRLVPGGGATEIELAKQITSYGETCPGL 433
           TI+LRG  +  M++ ER++ D +   +   ++  +V GGGA E+E++  +  +  T  G 
Sbjct: 465 TIILRGGAEQFMEETERSLHDAIMIVRRAIKNDSVVAGGGAIEMEVSYHLREHSHTIAGK 644

Query: 434 EQYAIKKFAEAFEAIPRALAENSGVKANEVISKLYSVHQEGNKNVGLDIEAEVPAVKDML 493
           EQ  +  +A+A E IPR L +N+G  A  +++KL   H +G    G++I  E   + D  
Sbjct: 645 EQLLMSAYAKALEVIPRQLCDNAGFDATNILNKLRQKHAQGGTWYGVNILRE--DIADNF 818

Query: 494 EASILDTYLGKYWAIKLATNAAVTVLRVDQII 525
           E  + +  + K  A+  A+ A   +L VD+ I
Sbjct: 819 EDCVWEPAVVKINALTAASEATALILSVDETI 914
>29864
          Length = 1026

 Score = 72.0 bits (175), Expect = 6e-13,   Method: Compositional matrix adjust.
 Identities = 69/270 (25%), Positives = 118/270 (43%), Gaps = 15/270 (5%)
 Frame = +1

Query: 27  EAVYRNIQACKELAQTTRTAYGPNGMNKMVINRLEKLFVTNDAATILRELEVQHPAAKMI 86
           +A+  NI A K L    R+  GP G  KM+++    + +T D   +L E+++QHP A +I
Sbjct: 160 QALAVNIAAAKGLQDVLRSNLGPKGTMKMLVSGAGDIKLTKDGNVLLHEMQIQHPTASLI 339

Query: 87  VMASHMQEQEVGDGTNFVLVFXXXXXXXXXXXXRIGLSVSEVISGYEIACKKAHEILPEL 146
              +  Q+   GDGT   ++               GL    +  G+E+A  KA E+L E+
Sbjct: 340 ARVATAQDDITGDGTTSNVLIIGELLKQADLYIAEGLHPRLITEGFELARNKALEVLEEV 519

Query: 147 VCCSAKNLRDVDE--VSSLLRTSIMSKQYGSETFLAKLIAQ----ACVSIFPDSGNFNVD 200
                K  R+VD   +  + RTS+ +K +   T LA L+ +    A ++I       ++ 
Sbjct: 520 -----KVKREVDRETLVQVARTSLRTKVH---TELADLLTEHVVDAVLAIQXPGEGIDLH 675

Query: 201 NIRVCKILGSGIYSSSVLHGMV---------FKKETEGDVTSVKDAKIAVYSCPFDGMIT 251
            + + ++       S+++ G+V          KK T       KDA I   +   +   T
Sbjct: 676 MVELMEMQHKTDLDSTLVRGLVMDHGARHPDMKKHT-------KDAFILTCNVSLEYEKT 834

Query: 252 ETKGTVLIKTAEELMNFSKGEENLMDAQVK 281
           E       KTA+E     + E   +D +V+
Sbjct: 835 EVNSGFFYKTAQEREKLVEAERTFIDERVR 924
>02673
          Length = 1243

 Score = 67.8 bits (164), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 40/112 (35%), Positives = 62/112 (55%)
 Frame = +1

Query: 413 GATEIELAKQITSYGETCPGLEQYAIKKFAEAFEAIPRALAENSGVKANEVISKLYSVHQ 472
           GA EI  +  +    +    LEQYA++ F+EA EA+P ALAENSG+   + ++++ S  Q
Sbjct: 1   GAPEIAASVAVAEAADKISTLEQYAVRSFSEALEAVPLALAENSGLAPIQTLAEVKS-RQ 177

Query: 473 EGNKNVGLDIEAEVPAVKDMLEASILDTYLGKYWAIKLATNAAVTVLRVDQI 524
              KN  L I+  +    DM E ++++T   K   I LAT     +L++D I
Sbjct: 178 VKEKNPRLGIDCLLKGTNDMKEQNVIETLTAKKQQILLATQLVRMILKIDDI 333
>33770
          Length = 484

 Score = 59.7 bits (143), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 51/153 (33%), Positives = 76/153 (49%), Gaps = 5/153 (3%)
 Frame = +1

Query: 65  VTNDAATILRELEVQHPAAKMIVMASHMQEQEVGDGTNFVLVFXXXXXXXXXXXXRIGLS 124
           +TND ATIL++++V HPAAKM+V  S  Q+ E GDGT  V+V               G+ 
Sbjct: 34  ITNDGATILKQMQVLHPAAKMLVELSKAQDIEXGDGTTTVVVLAGSLLDASAKLLAKGIH 213

Query: 125 VSEVISGYEIACKKAHEILPELVCCSAKNLRDVDEVSSLLRTSIMSK---QYGSETFLAK 181
            + +   ++ A  K  E+L  +V      L D + + S   TS+ SK   QY S   LA 
Sbjct: 214 PTMISEAFQKAASKCVELLDGMV--KPLELSDRESLLSSASTSLNSKVVSQYSS--MLAP 381

Query: 182 LIAQACVSIFPDSGNFNVD--NIRVCKILGSGI 212
           +   A + +   +   NVD  +I++ K LG  I
Sbjct: 382 IAVDAVLKVIDPATATNVDLKDIKIIKKLGGTI 480
>34332
          Length = 714

 Score = 56.2 bits (134), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 25/31 (80%), Positives = 28/31 (90%)
 Frame = -1

Query: 413 GATEIELAKQITSYGETCPGLEQYAIKKFAE 443
           G  EIELAKQIT+YGE+ PGLEQYA+KKFAE
Sbjct: 93  GGKEIELAKQITTYGESLPGLEQYAVKKFAE 1
>30661
          Length = 380

 Score = 54.3 bits (129), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 32/111 (28%), Positives = 57/111 (51%)
 Frame = +3

Query: 339 PVQEEMGHCDSVYLSEVGDTQVVVFKHEKEDGAISTIVLRGSTDNLMDDIERAVDDGVNT 398
           P + ++G CD +    +G+ +++ F      G   TIVLRG+T  ++D+  R++ D +  
Sbjct: 60  PEKTKLGQCDLIEEVMIGEDKLIKFSGVAL-GEACTIVLRGATQQILDEAXRSLHDALCV 236

Query: 399 FKVLTRDKRLVPGGGATEIELAKQITSYGETCPGLEQYAIKKFAEAFEAIP 449
                ++ R V GGG +E+ +A+ ++      PG       K A A EA+P
Sbjct: 237 LSQTVKETRTVYGGGCSEMLMAEAVSQLAAKTPG-------KEAIAMEALP 368
>15785
          Length = 402

 Score = 47.4 bits (111), Expect = 2e-05,   Method: Composition-based stats.
 Identities = 22/52 (42%), Positives = 32/52 (61%)
 Frame = -1

Query: 181 KLIAQACVSIFPDSGNFNVDNIRVCKILGSGIYSSSVLHGMVFKKETEGDVT 232
           K+I   CV ++          +RVCKILG G+  SS + GMVFK++ EG++T
Sbjct: 126 KII*SVCVHVY----------VRVCKILGCGLLQSSTIQGMVFKRQVEGEIT 1
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6753324|ref|NP_033968.1| chaperonin containing Tcp1,
subunit 6a [Mus musculus]
         (531 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

29864                                                                 439   e-123
01159                                                                 217   1e-56
05356                                                                  89   2e-34
09900                                                                 108   6e-24
29631                                                                 100   2e-21
06409                                                                  89   6e-18
33770                                                                  85   6e-17
12796                                                                  82   6e-16
17249                                                                  45   5e-05
30661                                                                  28   8.2  
>29864
          Length = 1026

 Score =  439 bits (1129), Expect = e-123,   Method: Compositional matrix adjust.
 Identities = 210/273 (76%), Positives = 245/273 (89%)
 Frame = +1

Query: 1   MAAVKTLNPKXXXXXXXXXXXVNISAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDG 60
           M+A+K LNPK           VNI+AA+GLQDVLR+NLGPKGTMKMLVSGAGDIKLTKDG
Sbjct: 109 MSAIKQLNPKAEVARASQALAVNIAAAKGLQDVLRSNLGPKGTMKMLVSGAGDIKLTKDG 288

Query: 61  NVLLHEMQIQHPTASLIAKVATAQDDITGDGTTSNVLIIGELLKQADLYISEGLHPRIIT 120
           NVLLHEMQIQHPTASLIA+VATAQDDITGDGTTSNVLIIGELLKQADLYI+EGLHPR+IT
Sbjct: 289 NVLLHEMQIQHPTASLIARVATAQDDITGDGTTSNVLIIGELLKQADLYIAEGLHPRLIT 468

Query: 121 EGFEAAKEKALQFLEQVKVSKEMDRETLIDVARTSLRTKVHAELADVLTEAVVDSILAIR 180
           EGFE A+ KAL+ LE+VKV +E+DRETL+ VARTSLRTKVH ELAD+LTE VVD++LAI+
Sbjct: 469 EGFELARNKALEVLEEVKVKREVDRETLVQVARTSLRTKVHTELADLLTEHVVDAVLAIQ 648

Query: 181 KKDEPIDLFMVEIMEMKHKSETDTSLIRGLVLDHGARHPDMKKRVENAYILTCNVSLEYE 240
              E IDL MVE+MEM+HK++ D++L+RGLV+DHGARHPDMKK  ++A+ILTCNVSLEYE
Sbjct: 649 XPGEGIDLHMVELMEMQHKTDLDSTLVRGLVMDHGARHPDMKKHTKDAFILTCNVSLEYE 828

Query: 241 KTEVNSGFFYKSAEEREKLVKAERKFIEDRVKK 273
           KTEVNSGFFYK+A+EREKLV+AER FI++RV+K
Sbjct: 829 KTEVNSGFFYKTAQEREKLVEAERTFIDERVRK 927

 Score = 39.7 bits (91), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 16/26 (61%), Positives = 23/26 (88%)
 Frame = +2

Query: 184 EPIDLFMVEIMEMKHKSETDTSLIRG 209
           E IDL MVE+MEM+HK++ D++L+RG
Sbjct: 2   EGIDLHMVELMEMQHKTDLDSTLVRG 79
>01159
          Length = 2613

 Score =  217 bits (552), Expect = 1e-56,   Method: Compositional matrix adjust.
 Identities = 159/510 (31%), Positives = 267/510 (52%), Gaps = 11/510 (2%)
 Frame = +3

Query: 23  NISAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDGNVLLHEMQIQHPTASLIAKVAT 82
           +I AA+ +  +L+T+LGPKG  KM+VSG GD+ +T DG  +L  M + H  A L+ +++ 
Sbjct: 201 HILAAKSVASILKTSLGPKGLDKMMVSGDGDVTVTNDGATILDMMDVDHQIAKLMVQLSK 380

Query: 83  AQDDITGDGTTSNVLIIGELLKQADLYISEGLHPRIITEGFEAAKEKALQFLEQVKVSKE 142
           +QDD  GDGTT  V++ G LL+QA+  +  G+HP  I +G+E A + A++ L+++  + E
Sbjct: 381 SQDDEIGDGTTGVVVLAGALLEQAEKLLDRGIHPIRIADGYEIAAKCAVETLDKISDNYE 560

Query: 143 MD---RETLIDVARTSLRTKV----HAELADVLTEAVVDSILAIRKKDEPIDLFMVEIME 195
           +D    E LI +A T+L +K+    H ++A +  +A++ S+  +++KD   +L  VE  +
Sbjct: 561 VDLKNAEPLIKLAMTTLGSKIVNRCHRQMAKIAVDAIM-SVADLKRKDVDFELIKVE-GK 734

Query: 196 MKHKSETDTSLIRGLVLDHGARHPDMKKRVENAYILTCNVSLEYEKTEVNSGFFYKSAEE 255
           +  K E DT L++G+V+D    HP M K V++A I       E  K +        S E+
Sbjct: 735 VGGKLE-DTMLVKGVVVDKDMSHPQMPKVVKDAKIAILTCPFEPPKPKTKHKLDITSVED 911

Query: 256 REKLVKAERKFIEDRVKKIIELKKKVCGDSDKGF-VVINQKGIDPFSLDALAKEGIVALR 314
            +KL + E    E  V+ +           DKG  +VI Q G D  +   L +  + A+R
Sbjct: 912 YKKLREYELNKFESMVQSV----------KDKGANLVICQWGFDDEANHLLLQRELPAVR 1061

Query: 315 RAKRRNMERLTLACGGIALNSFDDLNPDCLGHAGLVYEYTLG--EEKFTFIEKCNNPRSV 372
                 +E + +A GG  +  F++L  + LG AG+V E T G  +++   IE+C N R+V
Sbjct: 1062WVGGPEIELIAIATGGRIVPRFEELTTEKLGKAGIVRELTFGTTKDRMLVIEECLNTRAV 1241

Query: 373 TLLVKGPNKHTLTQIKDAIRDGLRAVKNAIDDGCVVPXXXXXXXXXXXXXIKYKPSVKGR 432
           T+ ++G NK  + + K ++ D L  ++N + D  VV               +    +   
Sbjct: 1242TIFIRGGNKMIVEEAKRSLHDALCVIRNLVRDNRVVYGGGAPEIAASVAVAEAADKISTL 1421

Query: 433 AQLGVQAFADALLIIPKVLAQNSGFDLQETLVKVQAEH-SESGQLVGVDLSTGEPMVAAE 491
            Q  V++F++AL  +P  LA+NSG    +TL +V++    E    +G+D          E
Sbjct: 1422EQYAVRSFSEALEAVPLALAENSGLAPIQTLAEVKSRQVKEKNPRLGIDCLLKGTNDMKE 1601

Query: 492 MGVWDNYCVKKQLLHSCTVIATNILLVDEI 521
             V +    KKQ +   T +   IL +D+I
Sbjct: 1602QNVIETLTAKKQQILLATQLVRMILKIDDI 1691
>05356
          Length = 2339

 Score = 88.6 bits (218), Expect(2) = 2e-34,   Method: Compositional matrix adjust.
 Identities = 73/260 (28%), Positives = 123/260 (47%), Gaps = 6/260 (2%)
 Frame = +2

Query: 23  NISAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDGNVLLHEMQIQHPTASLIAKVAT 82
           NI A + L    R+  GP G  KM+++    + +T D   +L E+++QHP A ++   A 
Sbjct: 284 NIEACKELAKTTRSAYGPHGQNKMVINHLEKLFVTNDAATILRELEVQHPAAKMLVLAAH 463

Query: 83  AQDDITGDGTTSNVLIIGELLKQADLYISEGLHPRIITEGFEAAKEKALQFLEQV---KV 139
            Q+   GDGT   ++  G LL+ A+  +  GL    + EG+E A +KA + L ++    V
Sbjct: 464 QQEQECGDGTNFVLVFAGALLENAEQLLRMGLSVTEVIEGYELALKKAHEILPKLVIGHV 643

Query: 140 SKEMDRETLIDVARTSLRTKVHAE---LADVLTEAVVDSILAIRKKDEPIDLFMVEIMEM 196
               ++E +    RTS+ +K +     LAD++T+A V  + A  K    +D   V + ++
Sbjct: 644 KNLRNKEEVKTAIRTSVMSKQYGNEDFLADLITDACVSVLPA--KISFSVD--NVRVCKI 811

Query: 197 KHKSETDTSLIRGLVLDHGARHPDMKKRVENAYILTCNVSLEYEKTEVNSGFFYKSAEER 256
                  +S I+G+V          K       + TC   L+  +TE       K+AEE 
Sbjct: 812 LGCGLLQSSTIQGMVFKRQVEGEITKVEKAKVAVFTC--PLDSMQTETKGTVLIKNAEEL 985

Query: 257 EKLVKAERKFIEDRVKKIIE 276
               K E   +E+++K I E
Sbjct: 986 MSFSKGEEDMMEEQIKGIKE 1045

 Score = 75.5 bits (184), Expect(2) = 2e-34,   Method: Compositional matrix adjust.
 Identities = 56/220 (25%), Positives = 99/220 (45%), Gaps = 2/220 (0%)
 Frame = +1

Query: 307  KEGIVALRRAKRRNMERLTLACGGIALNSFDDLNPDCLGHAGLVYEYTLGEEKFTFIEKC 366
            K  ++ +R   + ++ RL  +    AL        +  G+  LVY   +GE      ++ 
Sbjct: 1108 KYKVMVIRLLSKWDLRRLCKSICATALPKVTTPRNEECGYCDLVYVDEIGETPVVIFQQN 1287

Query: 367  NNPRSVT-LLVKGPNKHTLTQIKDAIRDGLRAVKNAIDDGCVVPXXXXXXXXXXXXXIKY 425
             +   +T ++++G   + +  I+ A+ DG+   K    D  +VP               Y
Sbjct: 1288 KDESPITTVIIRGSTDNIMDDIERALDDGVNTFKALTKDDRLVPGAGATEIELAKQITTY 1467

Query: 426  KPSVKGRAQLGVQAFADALLIIPKVLAQNSGFDLQETLVKVQAEHSESGQLVGVDL-STG 484
              S+ G  Q  V+ FA++L +IP+ LA+N+G    + L K+ A H E  Q  GVD+  +G
Sbjct: 1468 GESLPGLEQYAVKKFAESLEVIPRALAENTGMKATDILSKLYAAHQEGQQNAGVDIDDSG 1647

Query: 485  EPMVAAEMGVWDNYCVKKQLLHSCTVIATNILLVDEIMRA 524
              + A +  + D Y  +   L      A  +L VD+I+ A
Sbjct: 1648 SVLDAKQANLTDLYLNRYWGLKFAAAAACTVLRVDQIIMA 1767
>09900
          Length = 1305

 Score =  108 bits (270), Expect = 6e-24,   Method: Compositional matrix adjust.
 Identities = 74/290 (25%), Positives = 133/290 (45%)
 Frame = +3

Query: 234 NVSLEYEKTEVNSGFFYKSAEEREKLVKAERKFIEDRVKKIIELKKKVCGDSDKGFVVIN 293
           N+ LE +    N+     + +E + +V AE K + D++ KI +   KV         V++
Sbjct: 75  NIELELKSERDNAEVRVDNVQEYQSIVDAEWKILYDKLDKIHQSGAKV---------VLS 227

Query: 294 QKGIDPFSLDALAKEGIVALRRAKRRNMERLTLACGGIALNSFDDLNPDCLGHAGLVYEY 353
           +  I   +    A   +    R    ++ R   ACGG    +   L PD LG   L  E 
Sbjct: 228 KLPIGDVATQYFADRDMFCAGRVPEEDLRRTMKACGGSIQTTVQSLTPDVLGTCQLFDEI 407

Query: 354 TLGEEKFTFIEKCNNPRSVTLLVKGPNKHTLTQIKDAIRDGLRAVKNAIDDGCVVPXXXX 413
            +G E+F   + C   R+ T++++G  +  + + + ++ D +  V+ AI +  VV     
Sbjct: 408 QIGGERFNMFKGCTMARTCTIILRGGAEQFMEETERSLHDAIMIVRRAIKNDSVVAGGGA 587

Query: 414 XXXXXXXXXIKYKPSVKGRAQLGVQAFADALLIIPKVLAQNSGFDLQETLVKVQAEHSES 473
                     ++  ++ G+ QL + A+A AL +IP+ L  N+GFD    L K++ +H++ 
Sbjct: 588 IEMEVSYHLREHSHTIAGKEQLLMSAYAKALEVIPRQLCDNAGFDATNILNKLRQKHAQG 767

Query: 474 GQLVGVDLSTGEPMVAAEMGVWDNYCVKKQLLHSCTVIATNILLVDEIMR 523
           G   GV++   +     E  VW+   VK   L + +     IL VDE ++
Sbjct: 768 GTWYGVNILREDIADNFEDCVWEPAVVKINALTAASEATALILSVDETIK 917
>29631
          Length = 1257

 Score = 99.8 bits (247), Expect = 2e-21,   Method: Compositional matrix adjust.
 Identities = 49/122 (40%), Positives = 77/122 (63%)
 Frame = +3

Query: 23  NISAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDGNVLLHEMQIQHPTASLIAKVAT 82
           NI+A + + DV+RT LGPK  +KML+   G I +T DGN +L E+ +QHP A  + +VA 
Sbjct: 60  NIAAGKTIADVIRTCLGPKSMLKMLMDPMGGIVMTNDGNAILREINVQHPAAKSMIEVAR 239

Query: 83  AQDDITGDGTTSNVLIIGELLKQADLYISEGLHPRIITEGFEAAKEKALQFLEQVKVSKE 142
            QD+ TGDGT S +++ GE+L  A+ ++ + +HP +I   +  A E  L+ L + K+   
Sbjct: 240 TQDEETGDGTKSVIILAGEVLSVAEQFLEQQMHPTVIIAAYRQALEDTLEVL-RTKICTP 416

Query: 143 MD 144
           +D
Sbjct: 417 ID 422

 Score = 71.2 bits (173), Expect = 9e-13,   Method: Compositional matrix adjust.
 Identities = 50/191 (26%), Positives = 87/191 (45%), Gaps = 1/191 (0%)
 Frame = +1

Query: 203 DTSLIRGLVLDHGARHPDMKKRVENAYILTCNVSLEYEKTEVNSGFFYKSAEEREKLVKA 262
           ++ +++G+ ++    H  MK+R+EN  I+  + +LEY+K E  +       E+  K+++ 
Sbjct: 619 ESEVLKGIXVNKDVVHXKMKRRIENPRIMLLDCNLEYKKGESATNIEISKEEDFAKILQL 798

Query: 263 ERKFIEDRVKKIIELKKKVCGDSDKGFVVINQKGIDPFSLDALAKEGIVALRRAKRRNME 322
           E ++I     +II LK           +VI +KG+   +   L K GI  LRR ++ +  
Sbjct: 799 EEEYIRKMCDEIIALKPD---------LVITEKGVSDLAQHFLLKAGISVLRRVRKTDNN 951

Query: 323 RLTLACGGIALNSFDDLNPDCLGH-AGLVYEYTLGEEKFTFIEKCNNPRSVTLLVKGPNK 381
           R+  ACG    N  D+L  + +G   GL+    L           N PR      +GP K
Sbjct: 952 RIARACGATIANRTDELKEEDMGSGCGLLKCARLAMTTSRSWWTANRPRRARSC*EGPAK 1131

Query: 382 HTLTQIKDAIR 392
            +  +     R
Sbjct: 1132TSWRKWSATCR 1164
>06409
          Length = 1533

 Score = 88.6 bits (218), Expect = 6e-18,   Method: Compositional matrix adjust.
 Identities = 79/316 (25%), Positives = 143/316 (45%), Gaps = 8/316 (2%)
 Frame = -3

Query: 215  GARHPDMKKRVENAYILTCNVSLEYEKTEVNSGFFYKSAEEREKLVKAERKFIEDRVKKI 274
            GA  P   ++ +  +I  C   +   KT++ +        + +++++ ER +I D VKKI
Sbjct: 1513 GAGGPSKVEKAKIGFIQFC---ISPPKTDMENQVIVSDYTQMDRVLREERNYILDIVKKI 1343

Query: 275  IELKKKVCGDSDKGFVVINQKGI-----DPFSLDALAKEGIVALRRAKRRNMERL--TLA 327
               KK  C       V++ QK I        +L  LAK  I+ ++  +R ++E +  TL 
Sbjct: 1342 ---KKAGCN------VLLIQKSILRDAVSDLALHFLAKMKIMVVKDIEREDVEFVCKTLG 1190

Query: 328  CGGIALNSFDDLNPDCLGHAGLVYEYTLGEEKFTFIEKCNNP-RSVTLLVKGPNKHTLTQ 386
            C  +A  S D   P+ LG A L+ E   G  K        NP ++VT+L++G NK  L +
Sbjct: 1189 CRPVA--SLDHFLPENLGSADLIEEVQTGSSKIVKATGIANPGQTVTVLIRGSNKLVLEE 1016

Query: 387  IKDAIRDGLRAVKNAIDDGCVVPXXXXXXXXXXXXXIKYKPSVKGRAQLGVQAFADALLI 446
               ++ D L  ++  +    ++                Y  ++ G  Q   +AFA+AL +
Sbjct: 1015 ADRSLHDALCVIRCLVKKKALIAGGGAPETEMSMRLAAYANTLAGMEQYCFRAFAEALEV 836

Query: 447  IPKVLAQNSGFDLQETLVKVQAEHSESGQLVGVDLSTGEPMVAAEMGVWDNYCVKKQLLH 506
            IP  LA+N+G +   T+  ++  H++  +  G+++  G      E  V     V    + 
Sbjct: 835  IPFTLAENAGLNPISTVTXLRTRHAQGERTAGINVRKGAITNILEENVLQPLLVSTSAIT 656

Query: 507  SCTVIATNILLVDEIM 522
              +    +IL +D+I+
Sbjct: 655  LASETVRSILKIDDIV 608
>33770
          Length = 484

 Score = 85.1 bits (209), Expect = 6e-17,   Method: Compositional matrix adjust.
 Identities = 50/136 (36%), Positives = 87/136 (63%), Gaps = 1/136 (0%)
 Frame = +1

Query: 45  KMLVSGAGDIKLTKDGNVLLHEMQIQHPTASLIAKVATAQDDITGDGTTSNVLIIGELLK 104
           KM+ +  GD+ +T DG  +L +MQ+ HP A ++ +++ AQD   GDGTT+ V++ G LL 
Sbjct: 1   KMIQAANGDVTITNDGATILKQMQVLHPAAKMLVELSKAQDIEXGDGTTTVVVLAGSLLD 180

Query: 105 QADLYISEGLHPRIITEGFEAAKEKALQFLE-QVKVSKEMDRETLIDVARTSLRTKVHAE 163
            +   +++G+HP +I+E F+ A  K ++ L+  VK  +  DRE+L+  A TSL +KV ++
Sbjct: 181 ASAKLLAKGIHPTMISEAFQKAASKCVELLDGMVKPLELSDRESLLSSASTSLNSKVVSQ 360

Query: 164 LADVLTEAVVDSILAI 179
            + +L    VD++L +
Sbjct: 361 YSSMLAPIAVDAVLKV 408
>12796
          Length = 1316

 Score = 81.6 bits (200), Expect = 6e-16,   Method: Compositional matrix adjust.
 Identities = 76/307 (24%), Positives = 140/307 (45%), Gaps = 8/307 (2%)
 Frame = -3

Query: 186  IDLFMVEIMEMKHKSETDTSLIRGLVLDHGARHPDMKKRVENAYILTCNVSLEYEKTEVN 245
            +DL  ++++     +  DT L+ GLV    +   +  KR+E A I      +   KT+++
Sbjct: 1308 VDLKNIKVIRSLGGTVEDTELVNGLVFTSRSAGTNAPKRIEKAKIGLIQFCISAPKTDMD 1129

Query: 246  SGFFYKSAEEREKLVKAERKFIEDRVKKIIELKKKVCGDSDKGFVVINQKGIDPFSLDAL 305
                       ++++K ER +I + VK+I   KK  C       V++ QK I   ++  L
Sbjct: 1128 HNVIVSDYAAMDRVLKEERSYILNIVKQI---KKAGCN------VLLVQKSILRDAVSDL 976

Query: 306  AKEGI-----VALRRAKRRNMERL--TLACGGIALNSFDDLNPDCLGHAGLVYEYTLGEE 358
            A+  +     + ++  +R ++E +  TL C  IA  S D    + +  A LV E   G  
Sbjct: 975  AQHFLDKIKCLVVKDVEREDIEFVCKTLHCRPIA--SLDHFTAENMSSADLVEEVASGTN 802

Query: 359  KFTFIEKCNNP-RSVTLLVKGPNKHTLTQIKDAIRDGLRAVKNAIDDGCVVPXXXXXXXX 417
            KF  I    N  R+V+++ +G NK  L +   ++ D L  V+  + +   +         
Sbjct: 801  KFVKITGIQNQGRTVSIICRGSNKLVLEEAARSLHDALCVVRCLVRNRAQIVGGGAPEIE 622

Query: 418  XXXXXIKYKPSVKGRAQLGVQAFADALLIIPKVLAQNSGFDLQETLVKVQAEHSESGQLV 477
                      +V G      +AFADAL +IP  LA+N+G +   T+ +++  H++  +  
Sbjct: 621  MALQLAAAAQTVDGVDAYCYRAFADALEVIPSTLAENAGLNPIATVTELRNRHAQGEKNA 442

Query: 478  GVDLSTG 484
            G+++  G
Sbjct: 441  GINVRKG 421
>17249
          Length = 909

 Score = 45.4 bits (106), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 32/93 (34%), Positives = 50/93 (53%), Gaps = 8/93 (8%)
 Frame = +3

Query: 443 ALLIIPKVLAQNSGFDLQETLVKVQAEHSESGQ--LVGVDLSTGEPMVAAEMGVWDNYCV 500
           AL +I + L QN G +   TL  ++A+H++ GQ    G+D +TG  +  AE G+W+   V
Sbjct: 12  ALEVISRTLIQNCGANTIRTLTALRAKHAQ-GQKNTWGIDGNTGNIVDMAEFGIWEPLSV 188

Query: 501 KKQLLHSCTVIATNILLVDEI------MRAGMS 527
           K Q+  +    A  +L +D+I      M A MS
Sbjct: 189 KLQVYKTACETAILLLRIDDIVSGTKKMDAAMS 287
>30661
          Length = 380

 Score = 28.1 bits (61), Expect = 8.2,   Method: Compositional matrix adjust.
 Identities = 16/76 (21%), Positives = 33/76 (43%)
 Frame = +3

Query: 329 GGIALNSFDDLNPDCLGHAGLVYEYTLGEEKFTFIEKCNNPRSVTLLVKGPNKHTLTQIK 388
           GG   ++FD      LG   L+ E  +GE+K           + T++++G  +  L +  
Sbjct: 30  GGEITSTFDCPEKTKLGQCDLIEEVMIGEDKLIKFSGVALGEACTIVLRGATQQILDEAX 209

Query: 389 DAIRDGLRAVKNAIDD 404
            ++ D L  +   + +
Sbjct: 210 RSLHDALCVLSQTVKE 257
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|8392847|ref|NP_058556.1| ARP1 actin-related protein 1
homolog A, centractin alpha [Mus musculus]
         (376 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

04742                                                                 436   e-123
12322                                                                 372   e-103
39562                                                                 355   2e-98
02757                                                                 141   2e-63
00608                                                                 181   6e-46
32273                                                                 180   1e-45
01436                                                                 131   4e-31
19721                                                                  92   4e-30
36954                                                                 117   5e-27
18926                                                                  94   1e-19
11487                                                                  66   4e-19
13361                                                                  87   1e-17
26639                                                                  31   0.66 
00310                                                                  28   4.3  
04121                                                                  28   4.7  
14855                                                                  28   6.8  
>04742
          Length = 2111

 Score =  436 bits (1120), Expect = e-123,   Method: Compositional matrix adjust.
 Identities = 198/369 (53%), Positives = 275/369 (74%), Gaps = 4/369 (1%)
 Frame = +2

Query: 12  VVIDNGSGVIKAGFAGDQIPKYCFPNYVGRPKHVRVMAGALEGDIFIGPKAEEHRGLLSI 71
           +VIDNGSG+ KAGFAGD  P+  FP+ VGRP+H  VM G  + D ++G +A+  RG+L++
Sbjct: 116 LVIDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTL 295

Query: 72  RYPMEHGIVKDWNDMERIWQYVYSKDQLQTFSEEHPVLLTEAPLNPRKNRERAAEVFFET 131
           +YP+EHGIV +W+DME+IW + +  ++L+   EEHPVLLTEAPLNP+ NRE+  ++ FET
Sbjct: 296 KYPIEHGIVTNWDDMEKIWHHTF-YNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFET 472

Query: 132 FNVPALFISMQAVLSLYATGRTTGVVLDSGDGVTHAVPIYEGFAMPHSIMRIDIAGRDVS 191
           FN PA+++++QAVLSLYA+GRTTG+VLDSGDGV H VPIYEG+A+PH+I R+D+AGRD++
Sbjct: 473 FNSPAMYVAIQAVLSLYASGRTTGIVLDSGDGVXHTVPIYEGYALPHAISRLDLAGRDLT 652

Query: 192 RFLRLYLRKEGYDFHSSSEFEIVKAIKERACYLSIN-PQKDETLETEKA---QYYLPDGS 247
            +L   L + GY F +++E EIV+ IKE+ CY++++  Q+ +T  +  +    Y LPDG 
Sbjct: 653 DYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMQTAASSSSLEKSYELPDGQ 832

Query: 248 TIEIGPSRFRAPELLFRPDLIGEESEGIHEVLVFAIQKSDMDLRRTLFSNIVLSGGSTLF 307
            I IG  RFR PE +F+P  +G ES G HE    +I K D+D+R+ L++N VLSGGST++
Sbjct: 833 VITIGNERFRCPEAMFQPSFLGMESAGXHETTYNSIMKCDVDIRKDLYANTVLSGGSTMY 1012

Query: 308 KGFGDRLLSEVKKLAPKDVKIRISAPQERLYSTWIGGSILASLDTFKKMWVSKKEYEEDG 367
            G  DR+  E+  LAP  +KI+I AP ER YS WIGGSILASL TF++MW+SK+EY+E G
Sbjct: 1013PGIADRMQKEITALAPPTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESG 1192

Query: 368 ARSIHRKTF 376
              +HRK F
Sbjct: 1193PSIVHRKCF 1219
>12322
          Length = 849

 Score =  372 bits (955), Expect = e-103,   Method: Compositional matrix adjust.
 Identities = 170/213 (79%), Positives = 199/213 (93%)
 Frame = +1

Query: 164 VTHAVPIYEGFAMPHSIMRIDIAGRDVSRFLRLYLRKEGYDFHSSSEFEIVKAIKERACY 223
           VTHAVP+YEGFAMPHSIMR+D+AGRDV+R+LRL LRKEG D H+++EFE+VK IKER CY
Sbjct: 1   VTHAVPVYEGFAMPHSIMRVDVAGRDVTRYLRLLLRKEGMDLHTTAEFEVVKHIKERTCY 180

Query: 224 LSINPQKDETLETEKAQYYLPDGSTIEIGPSRFRAPELLFRPDLIGEESEGIHEVLVFAI 283
           LSINP K+E+++TEK  Y LPDG+T+E+GP+RFRAPELLFRPDLIGEE EGIHEVL ++I
Sbjct: 181 LSINPLKEESVDTEKVSYTLPDGNTVEVGPARFRAPELLFRPDLIGEECEGIHEVLSYSI 360

Query: 284 QKSDMDLRRTLFSNIVLSGGSTLFKGFGDRLLSEVKKLAPKDVKIRISAPQERLYSTWIG 343
           QKSD+DLR+TL+SNIVLSGGSTLFKGFGDRLLSE+KKLAPKD+KIRISAPQERLYSTWIG
Sbjct: 361 QKSDVDLRKTLYSNIVLSGGSTLFKGFGDRLLSELKKLAPKDIKIRISAPQERLYSTWIG 540

Query: 344 GSILASLDTFKKMWVSKKEYEEDGARSIHRKTF 376
            SILASLDTF+KMWVSK+EY E+G ++IHRKTF
Sbjct: 541 XSILASLDTFRKMWVSKREYHEEGVKAIHRKTF 639
>39562
          Length = 1438

 Score =  355 bits (911), Expect = 2e-98,   Method: Compositional matrix adjust.
 Identities = 162/302 (53%), Positives = 226/302 (74%), Gaps = 4/302 (1%)
 Frame = -2

Query: 79   IVKDWNDMERIWQYVYSKDQLQTFSEEHPVLLTEAPLNPRKNRERAAEVFFETFNVPALF 138
            IV +W+DME+IW + +  ++L+   EEHPVLLTEAPLNP+ NRE+  ++ FETFN PA++
Sbjct: 1437 IVTNWDDMEKIWHHTF-YNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNSPAMY 1261

Query: 139  ISMQAVLSLYATGRTTGVVLDSGDGVTHAVPIYEGFAMPHSIMRIDIAGRDVSRFLRLYL 198
            +++QAVLSLYA+GRTTG+VLDSGDGVTH VPIYEG+A+PH+IMR+D+AGRD++ +L   L
Sbjct: 1260 VAIQAVLSLYASGRTTGIVLDSGDGVTHTVPIYEGYALPHAIMRLDLAGRDLTDYLMKIL 1081

Query: 199  RKEGYDFHSSSEFEIVKAIKERACYLSINPQKD----ETLETEKAQYYLPDGSTIEIGPS 254
             + GY F +++E EIV+ IKE+  Y++++ +++     +  + +  Y LPDG  I IG  
Sbjct: 1080 TERGYSFTTTAEREIVRDIKEKLDYVALDFEQEMLTAASSSSLEKSYELPDGQVITIGNE 901

Query: 255  RFRAPELLFRPDLIGEESEGIHEVLVFAIQKSDMDLRRTLFSNIVLSGGSTLFKGFGDRL 314
            RFR PE +F+P  +G ES GIHE    +I K D+D+R+ L++N VLSGGST++ G  DR+
Sbjct: 900  RFRCPEAMFQPSFLGMESAGIHETTYNSIMKCDVDIRKDLYANTVLSGGSTMYPGIADRM 721

Query: 315  LSEVKKLAPKDVKIRISAPQERLYSTWIGGSILASLDTFKKMWVSKKEYEEDGARSIHRK 374
              E+  LAP  +KI+I AP ER YS WIGGSILASL TF++MW+SK+EY+E G   +HRK
Sbjct: 720  QKEITALAPPTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRK 541

Query: 375  TF 376
             F
Sbjct: 540  CF 535
>02757
          Length = 1094

 Score =  141 bits (355), Expect(3) = 2e-63,   Method: Compositional matrix adjust.
 Identities = 66/152 (43%), Positives = 99/152 (65%), Gaps = 4/152 (2%)
 Frame = -2

Query: 177 PHSIMRIDIAGRDVSRFLRLYLRKEGYDFHSSSEFEIVKAIKERACYLSINPQKDETLET 236
           P +I+R+D+AGRD++ +L   L + GY F +++E EIV  IKE+ CY++++ +++     
Sbjct: 997 PTAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVXDIKEKLCYVALDFEQEMATAA 818

Query: 237 EKAQ----YYLPDGSTIEIGPSRFRAPELLFRPDLIGEESEGIHEVLVFAIQKSDMDLRR 292
             +     Y LPDG  I IG  RFR PE LF+P  +G ES GIHE    +I K D+D+R+
Sbjct: 817 SSSSLEKSYELPDGQVITIGNERFRCPESLFQPSFLGMESAGIHETTYNSIMKCDVDIRK 638

Query: 293 TLFSNIVLSGGSTLFKGFGDRLLSEVKKLAPK 324
            L++N VLSGG+T+F G  DR+  E+  LAP+
Sbjct: 637 DLYANTVLSGGTTMFPGIADRMQKEITALAPQ 542

 Score = 73.6 bits (179), Expect(3) = 2e-63,   Method: Compositional matrix adjust.
 Identities = 32/51 (62%), Positives = 40/51 (78%)
 Frame = -3

Query: 326 VKIRISAPQERLYSTWIGGSILASLDTFKKMWVSKKEYEEDGARSIHRKTF 376
           +KI+  AP ER YS WIGGSILASL TF++MW+SK+EY+E G   +HRK F
Sbjct: 537 MKIKXIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF 385

 Score = 67.0 bits (162), Expect(3) = 2e-63,   Method: Compositional matrix adjust.
 Identities = 29/34 (85%), Positives = 33/34 (97%)
 Frame = -1

Query: 145  LSLYATGRTTGVVLDSGDGVTHAVPIYEGFAMPH 178
            LSLYA+GRTTG+VLDSGDGVTH VPIYEG+A+PH
Sbjct: 1094 LSLYASGRTTGIVLDSGDGVTHTVPIYEGYALPH 993
>00608
          Length = 1930

 Score =  181 bits (458), Expect = 6e-46,   Method: Compositional matrix adjust.
 Identities = 116/324 (35%), Positives = 182/324 (56%), Gaps = 35/324 (10%)
 Frame = +3

Query: 79  IVKDWNDMERIWQYVYSKDQLQTFSEEHPVLLTEAPLNPRKNRERAAEVFFETFNVPALF 138
           I+ DW+ MER ++ V  K  L+   E+H  LLTE PLN  +NRE  AE+ FE+FNVP L+
Sbjct: 3   IIDDWDLMERFYEQVIFK-YLRAEPEDHYFLLTEPPLNTPENREYTAEIMFESFNVPGLY 179

Query: 139 ISMQAVLSLYATGRT--------TGVVLDSGDGVTHAVPIYEGFAMPHSIMRIDIAGRDV 190
           I++QAVL+L A+  +        TG V+DSGDGVTH +P+ EG+ +   I  I IAGRD+
Sbjct: 180 IAVQAVLALAASWTSRNVGERTLTGTVIDSGDGVTHVIPVAEGYVIGSCIKHIPIAGRDI 359

Query: 191 SRFLRLYLRKEGYDFHSSSEFEIVKAIKERACYLSINPQKD----ETLETEKAQYYLPDG 246
           + F++  LR+           E  KAIKER  Y+  +  K+    +T  ++  + Y    
Sbjct: 360 TYFIQQLLREREVGIPPEQSLETAKAIKERFSYVCPDIAKEFSKYDTDPSKWMKKYEGRN 539

Query: 247 S------TIEIGPSRFRAPELLFRPDLIGEE-SEGIHEVLVFAIQKSDMDLRRTLFSNIV 299
           +      ++++G  RF  PE+ F P+    + +  I +V+   IQ   +D+RR L+ NIV
Sbjct: 540 TISKQLFSVDVGYERFLGPEIFFHPEFSNPDFTMPISDVVDDVIQNCPIDVRRGLYKNIV 719

Query: 300 LSGGSTLFKGFGDRLLSEVK----------------KLAPKDVKIRISAPQERLYSTWIG 343
           LSGGST+F+ FG ++  +VK                ++ PK +++++     + Y+ W G
Sbjct: 720 LSGGSTMFRDFGRKIQRDVKRVVDGRLKASEELSQGRIKPKPIEVQVITHHMQRYAVWFG 899

Query: 344 GSILASLDTFKKMWVSKKEYEEDG 367
           GS+LAS   F ++  +K +Y+E G
Sbjct: 900 GSMLASTPEFYQVCHTKADYDEHG 971
>32273
          Length = 265

 Score =  180 bits (456), Expect = 1e-45,   Method: Compositional matrix adjust.
 Identities = 81/88 (92%), Positives = 87/88 (98%)
 Frame = -2

Query: 68  LLSIRYPMEHGIVKDWNDMERIWQYVYSKDQLQTFSEEHPVLLTEAPLNPRKNRERAAEV 127
           L+SIRYPMEHGIVKDWNDMERIWQY+YSKDQLQTFSEEHPVLLTEAPLNPR+NRE+AAE+
Sbjct: 264 LMSIRYPMEHGIVKDWNDMERIWQYIYSKDQLQTFSEEHPVLLTEAPLNPRRNREKAAEI 85

Query: 128 FFETFNVPALFISMQAVLSLYATGRTTG 155
           FF+TFNVPALFISMQAVLSLYATGR TG
Sbjct: 84  FFDTFNVPALFISMQAVLSLYATGRITG 1
>01436
          Length = 2563

 Score =  131 bits (330), Expect = 4e-31,   Method: Compositional matrix adjust.
 Identities = 74/200 (37%), Positives = 114/200 (57%), Gaps = 16/200 (8%)
 Frame = +3

Query: 190 VSRFLRLYLRKEGYDFHSSSEFEIVKAIKERACYLSINPQKDETLETEKA----QYYLPD 245
           ++R+L   L   GY F+ S++FE V+ +KE+ CY + + ++++ L  E       Y LPD
Sbjct: 3   ITRYLIKLLLLRGYAFNHSADFETVRMLKEKLCYTAYDVEQEQKLALETTVLVEPYILPD 182

Query: 246 GSTIEIGPSRFRAPELLFRPDLIGEESEGIHEVLVFAIQKSDMDLRRTLFSNIVLSGGST 305
           G  I++G  RF APE LF+P LI  +  G+ E+L   IQ +DMD+R   + +IVLSGGST
Sbjct: 183 GRVIKVGGERFEAPEALFQPHLINVDGVGVAELLFNTIQAADMDIRPDFYKHIVLSGGST 362

Query: 306 LFKGFGDRLLSEVKKLAPKDV-----------KIRISAPQERLYSTWIGGSILASLDTFK 354
           ++ G   RL  E+K+L  + V           KIRI  P  R +  ++GGS+ A +   K
Sbjct: 363 MYPGLPSRLEREIKQLYLERVLXGDTSRLSKFKIRIEDPPRRKHMVFLGGSVXADIMKDK 542

Query: 355 -KMWVSKKEYEEDGARSIHR 373
              W+ + EYEE G + + +
Sbjct: 543 DDFWMMRSEYEEMGVKVLDK 602
>19721
          Length = 757

 Score = 91.7 bits (226), Expect(2) = 4e-30,   Method: Compositional matrix adjust.
 Identities = 55/121 (45%), Positives = 79/121 (65%), Gaps = 8/121 (6%)
 Frame = +2

Query: 79  IVKDWNDMERIWQYVYSKDQLQTFSEEHPVLLTEAPLNPRKNRERAAEVFFETFNVPALF 138
           +V+DW+  ER  +    K  L+   E+H  LLTE PLN  +NRE  AE+ FETFN+P L+
Sbjct: 2   VVEDWDLHERFMEQAIFK-YLRAEPEDHYFLLTEPPLNTPENREFTAEIMFETFNIPGLY 178

Query: 139 ISMQAVLSLYATGRT--------TGVVLDSGDGVTHAVPIYEGFAMPHSIMRIDIAGRDV 190
           I++QAVL+L A+  +        TG V+DSGDGVTH +P+ +G+ +  +I  I IAGRD+
Sbjct: 179 IAVQAVLALAASWTSRPPNERTLTGTVIDSGDGVTHVIPVVDGYVIGSAIKHIPIAGRDI 358

Query: 191 S 191
           +
Sbjct: 359 T 361

 Score = 57.8 bits (138), Expect(2) = 4e-30,   Method: Compositional matrix adjust.
 Identities = 38/109 (34%), Positives = 55/109 (50%), Gaps = 12/109 (11%)
 Frame = +3

Query: 212 EIVKAIKERACYLS-----------INPQKDETLETEKAQYYLPDGSTIEIGPSRFRAPE 260
           E  K IKER  Y+             +P+K             PD S  ++G  +F  PE
Sbjct: 420 EAAKQIKERYSYVCPDIAKEFAKYDSDPEKWIKAHKMSGSSKYPDFS-FDVGYEKFLGPE 596

Query: 261 LLFRPDLI-GEESEGIHEVLVFAIQKSDMDLRRTLFSNIVLSGGSTLFK 308
           + FRP+ + G+    I +V+   IQ   +D RR L++NIVLSGGS++FK
Sbjct: 597 VFFRPEFVNGDFQASISDVVDTVIQSCPIDSRRPLYNNIVLSGGSSMFK 743
>36954
          Length = 892

 Score =  117 bits (294), Expect = 5e-27,   Method: Compositional matrix adjust.
 Identities = 65/203 (32%), Positives = 111/203 (54%), Gaps = 13/203 (6%)
 Frame = -1

Query: 12  VVIDNGSGVIKAGFAGDQIPKYCFPNYVGRPKHVRVMAGALEGDIFIGPKAEEHRGLLSI 71
           +V D GS   +AG+AG+  PK   P +VG  + +        GD    P   E + L+  
Sbjct: 802 LVFDIGSYSFRAGYAGEDTPKAEIPTHVGVMEDIETTMDTDGGD---APPQPEKKYLIDT 632

Query: 72  RYPMEH-------------GIVKDWNDMERIWQYVYSKDQLQTFSEEHPVLLTEAPLNPR 118
            Y M+H             G+V+DW+  E++  Y Y++  +++ S  HP+L++E   N +
Sbjct: 631 VY-MKHPRKGMHLNSFLKDGMVEDWDMFEKVIDYAYNR-SIKSESCLHPLLMSEPAWNTK 458

Query: 119 KNRERAAEVFFETFNVPALFISMQAVLSLYATGRTTGVVLDSGDGVTHAVPIYEGFAMPH 178
             RE+  E+ FE +N+PA F+   +VLS +A GR+T ++LDSG   T AVP+Y+G+ +  
Sbjct: 457 AKREKLTEIMFEKYNIPAFFLRKNSVLSAFANGRSTALILDSGATHTSAVPVYDGYVLTQ 278

Query: 179 SIMRIDIAGRDVSRFLRLYLRKE 201
            I++  +AG  ++R   L + ++
Sbjct: 277 GIVKSPLAGDFIARECGLLMEEQ 209
>18926
          Length = 478

 Score = 93.6 bits (231), Expect = 1e-19,   Method: Compositional matrix adjust.
 Identities = 41/105 (39%), Positives = 70/105 (66%), Gaps = 3/105 (2%)
 Frame = +1

Query: 274 GIHEVLVFAIQKSDMDLRRTLFSNIVLSGGSTLFKGFGDRLLSEVKKLAPKDVKIRI--- 330
           G+  V+  ++   D+D+R +L+  ++  GG++L +GF +RL  ++    P  ++++I   
Sbjct: 97  GVGHVVTTSVGMCDIDIRPSLYGGVIAVGGNSLIQGFTERLNRDLSNKTPPSMRLKIIAA 276

Query: 331 SAPQERLYSTWIGGSILASLDTFKKMWVSKKEYEEDGARSIHRKT 375
           ++  ER +S+WIGGSILASL +F++MWVSK+EYEE G   + RK 
Sbjct: 277 ASTAERRFSSWIGGSILASLGSFQQMWVSKQEYEEGGKSCVERKC 411
>11487
          Length = 771

 Score = 66.2 bits (160), Expect(2) = 4e-19,   Method: Compositional matrix adjust.
 Identities = 28/42 (66%), Positives = 34/42 (80%)
 Frame = -2

Query: 335 ERLYSTWIGGSILASLDTFKKMWVSKKEYEEDGARSIHRKTF 376
           ER YS WIGGSILASL TF++MW+SK+EY+E G   +HRK F
Sbjct: 599 ERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF 474

 Score = 45.8 bits (107), Expect(2) = 4e-19,   Method: Compositional matrix adjust.
 Identities = 18/36 (50%), Positives = 27/36 (75%)
 Frame = -1

Query: 282 AIQKSDMDLRRTLFSNIVLSGGSTLFKGFGDRLLSE 317
           +I K D+D+R+ L++N VLSGG+T+F G  DR+  E
Sbjct: 756 SIMKCDVDIRKDLYANTVLSGGTTMFPGIADRMQKE 649
>13361
          Length = 1217

 Score = 86.7 bits (213), Expect = 1e-17,   Method: Compositional matrix adjust.
 Identities = 46/137 (33%), Positives = 75/137 (54%), Gaps = 17/137 (12%)
 Frame = +3

Query: 248 TIEIGPSRFRAPELLFRPDLIGEE-SEGIHEVLVFAIQKSDMDLRRTLFSNIVLSGGSTL 306
            +++G  RF  PE+ F P+    + +  + E++   IQ   +D+RR L++NIVLSGGST+
Sbjct: 150 NVDVGYERFLGPEIFFHPEFSNPDFTIPLSEIVDNVIQNCPIDVRRHLYNNIVLSGGSTM 329

Query: 307 FKGFGDRLLSEVK----------------KLAPKDVKIRISAPQERLYSTWIGGSILASL 350
           FK FG RL  ++K                ++ PK + +++     + Y+ W GGS+LAS 
Sbjct: 330 FKDFGRRLQRDIKRSVDTRLRISENLSEGRIKPKPIDVQVITHHMQRYAVWFGGSMLAST 509

Query: 351 DTFKKMWVSKKEYEEDG 367
             F ++  +K  YEE G
Sbjct: 510 PEFYQVCHTKAAYEEYG 560
>26639
          Length = 435

 Score = 31.2 bits (69), Expect = 0.66,   Method: Compositional matrix adjust.
 Identities = 16/37 (43%), Positives = 22/37 (59%)
 Frame = +2

Query: 44 HVRVMAGALEGDIFIGPKAEEHRGLLSIRYPMEHGIV 80
          H +V+AGALEGD+          G  +IR P++HG V
Sbjct: 71 HGKVLAGALEGDV----------GSTNIRXPVQHGHV 151
>00310
          Length = 2568

 Score = 28.5 bits (62), Expect = 4.3,   Method: Compositional matrix adjust.
 Identities = 12/23 (52%), Positives = 15/23 (65%)
 Frame = +3

Query: 250  EIGPSRFRAPELLFRPDLIGEES 272
            ++GP  F  PELL  PDL G E+
Sbjct: 2208 QLGPGWFLVPELLV*PDLAGSEA 2276
>04121
          Length = 1871

 Score = 28.5 bits (62), Expect = 4.7,   Method: Compositional matrix adjust.
 Identities = 16/44 (36%), Positives = 25/44 (56%), Gaps = 1/44 (2%)
 Frame = -1

Query: 257  RAPELLF-RPDLIGEESEGIHEVLVFAIQKSDMDLRRTLFSNIV 299
            R P L F R  LI   ++ + + ++FA+  S +D+  TLF  IV
Sbjct: 1673 RKPVLYFSRSPLINTTTQCVSKSVIFAVPPSTLDMECTLFVMIV 1542
>14855
          Length = 1907

 Score = 28.1 bits (61), Expect = 6.8,   Method: Compositional matrix adjust.
 Identities = 14/36 (38%), Positives = 21/36 (58%)
 Frame = +1

Query: 197  YLRKEGYDFHSSSEFEIVKAIKERACYLSINPQKDE 232
            +L +   +FH S EFE +K I  + CY S + Q +E
Sbjct: 994  FLHQAP*NFHVSKEFE*MKVINIKCCYESDSEQMEE 1101
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|19527174|ref|NP_598714.1| splicing factor 3b, subunit
3 [Mus musculus]
         (1217 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

08936                                                                 436   e-122
12525                                                                  46   1e-04
22154                                                                  43   7e-04
11182                                                                  32   1.6  
22462                                                                  30   4.8  
>08936
          Length = 1098

 Score =  436 bits (1120), Expect = e-122,   Method: Compositional matrix adjust.
 Identities = 194/258 (75%), Positives = 234/258 (90%)
 Frame = +3

Query: 960  LIGVGKLLRVYDLGKKKLLRKCENKHIANYISGIQTIGHRVIVSDVQESFIWVRYKRNEN 1019
            LIGVG+ LR+YDLGKKKLLRKCENKHI N+++ I T+GHRV+V D+Q+SF +VRY+R EN
Sbjct: 3    LIGVGRFLRIYDLGKKKLLRKCENKHIPNFVTTIHTLGHRVVVGDIQDSFHFVRYRRQEN 182

Query: 1020 QLIIFADDTYPRWVTTASLLDYDTVAGADKFGNICVVRLPPNTNDEVDEDPTGNKALWDR 1079
            QLI+FADDT PRW+T ++LLD++TVAGADKFGNI V+RLPP  +DEVDEDPTGNKALWDR
Sbjct: 183  QLIVFADDTTPRWITCSTLLDFNTVAGADKFGNINVIRLPPEVSDEVDEDPTGNKALWDR 362

Query: 1080 GLLNGASQKAEVIMNYHVGETVLSLQKTTLIPGGSESLVYTTLSGGIGILVPFTSHEDHD 1139
            G+L+GASQK E + ++H+GE V SLQK TLIPGGSE+LVYTTLSGGIG+LVPFTSH+DHD
Sbjct: 363  GVLSGASQKVETVASFHIGELVSSLQKATLIPGGSEALVYTTLSGGIGMLVPFTSHDDHD 542

Query: 1140 FFQHVEMHLRSEHPPLCGRDHLSFRSYYFPVKNVIDGDLCEQFNSMEPNKQKNVSEELDR 1199
            FFQH+EM++RSE P +CGRDHL++RSYYFP+KNVIDGDLCE FNSM+  KQ++V+EEL+R
Sbjct: 543  FFQHLEMYMRSEFPSICGRDHLAYRSYYFPLKNVIDGDLCEMFNSMDNAKQRSVAEELER 722

Query: 1200 TPPEVSKKLEDIRTRYAF 1217
            TP EVSKKLEDIRTRYAF
Sbjct: 723  TPSEVSKKLEDIRTRYAF 776
>12525
          Length = 698

 Score = 45.8 bits (107), Expect = 1e-04,   Method: Composition-based stats.
 Identities = 20/22 (90%), Positives = 21/22 (95%)
 Frame = +3

Query: 1196 ELDRTPPEVSKKLEDIRTRYAF 1217
            EL+RTP EVSKKLEDIRTRYAF
Sbjct: 360  ELERTPSEVSKKLEDIRTRYAF 425
>22154
          Length = 382

 Score = 43.1 bits (100), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 28/81 (34%), Positives = 42/81 (51%), Gaps = 2/81 (2%)
 Frame = -2

Query: 975  KKLLRKCENKH--IANYISGIQTIGHRVIVSDVQESFIWVRYKRNENQLIIFADDTYPRW 1032
            K+L  +C N +  IA Y+   +  G  V+V D+  S   + YK+ E QL   A D  P W
Sbjct: 381  KELRLECSNFNHIIALYV---KVKGDFVLVGDLMRSVSLLAYKQREGQLEEIARDCNPNW 211

Query: 1033 VTTASLLDYDTVAGADKFGNI 1053
            +T+  +LD D   GA+   N+
Sbjct: 210  MTSVEILDDDNFLGAENSFNL 148
>11182
          Length = 1960

 Score = 32.0 bits (71), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 15/43 (34%), Positives = 23/43 (53%)
 Frame = -1

Query: 772  AVFNQVAFPLQYTPRKFVIHPESNNLIIIETDHNAYTEATKAQ 814
            AVFNQV  P       +  HP+ +++ I +  H  Y  AT+A+
Sbjct: 1375 AVFNQVELPFTVNLNMYPTHPKGDSVAIAKKLHAKYKHATQAE 1247
>22462
          Length = 1416

 Score = 30.4 bits (67), Expect = 4.8,   Method: Composition-based stats.
 Identities = 14/49 (28%), Positives = 27/49 (55%)
 Frame = -3

Query: 975  KKLLRKCENKHIANYISGIQTIGHRVIVSDVQESFIWVRYKRNENQLII 1023
            +K+L  C+ KH  +++  +Q +G + I    +   ++ +YK   N LII
Sbjct: 1297 RKMLSDCQKKHFFHHLH-LQPLGPKYIHHKAKNVLVYTQYKTTWNVLII 1154
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|82930255|ref|XP_486227.3| PREDICTED: talin 2 isoform
1 [Mus musculus]
         (2543 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

09133                                                                 396   e-121
30501                                                                  77   7e-14
08616                                                                  65   5e-10
17332                                                                  49   2e-05
17228                                                                  40   0.015
30680                                                                  31   6.7  
>09133
          Length = 1844

 Score =  396 bits (1018), Expect(2) = e-121,   Method: Compositional matrix adjust.
 Identities = 240/448 (53%), Positives = 292/448 (65%), Gaps = 11/448 (2%)
 Frame = +1

Query: 2038 GAASTPDKXXXXXXXXXXXXXXXXEVVKLGAASLGSNDPETQVVLINAIKDVAKALSDLI 2097
            GAAS  ++                +VVK+GA SLG   PE QV+LINA+KDVA ALSDLI
Sbjct: 100  GAASNQEQLAAAAQAAVKTITRLADVVKIGAGSLGPEQPEAQVLLINAVKDVASALSDLI 279

Query: 2098 GATKGAASKPADDPSMYQLKGAAKVMVTNVTSLLKTVKAVEDEATRGTRALEATIEYIKQ 2157
             ATK A+ KP  DP+M  LK +AKVMVTNVTSLLKTVK+VEDEA RGTRALE+TIE I Q
Sbjct: 280  SATKNASGKPVSDPAMLHLKDSAKVMVTNVTSLLKTVKSVEDEAVRGTRALESTIEAIGQ 459

Query: 2158 EL------TVF---QSKDIPEKTSSPEESIRMTKGITMATAKAVAAGNSCRQEDVIATAN 2208
            E+      T F   Q + I   + SP    ++ + + +AT + V   +S           
Sbjct: 460  EVKALTPRTTFLARQRQKI*SDSPSP*-PWQLPRLLPLAT-RVVRKISSL-------PPT 612

Query: 2209 LSRKAVSDMLIACKQASFYPDVSEEVRTRALRYGTECTLGYLDLLEHVLVILQKPTPELK 2268
            L RK + ++    K  +     + E++ RAL  G    + Y +LLE+V  ++ +PT E +
Sbjct: 613  LGRKCIFELFGVIK-GAAATAETAEIKKRALNAGRSAAMTYKELLENVHQVVLRPTQEGR 789

Query: 2269 HQLAAFSKRVAGAVTELIQAAEAMKGTEWVDPEDPTVIAETXXXXXXXXXXXXXXXXXQL 2328
              LA  S++VA AVTEL+Q+AE +KGT+WVDP+DPTVIAE                  QL
Sbjct: 790  QNLALVSRKVANAVTELVQSAEVIKGTDWVDPDDPTVIAENELLSAASSIEAAAKKLSQL 969

Query: 2329 KPRAKPKQADETLDFEEQILEXXXXXXXXXXXLVKSASAAQRELVAQGKVGSIPANAA-- 2386
            KPR   K+ADE+L+F+EQILE           LVKSASAAQRELVAQGKV S     A  
Sbjct: 970  KPRQAAKKADESLNFDEQILEAAKSIAAATAALVKSASAAQRELVAQGKVSSTFTRHAVD 1149

Query: 2387 DDGQWSQGLISAARMVAAATSSLCEAANASVQGHASEEKLISSAKQVAASTAQLLVACKV 2446
            +DGQWSQGLISAARMVAAAT SLCEAANA VQGHASEEKLI+SAK+VA STAQLL+ACKV
Sbjct: 1150 EDGQWSQGLISAARMVAAATHSLCEAANAMVQGHASEEKLIASAKEVAGSTAQLLMACKV 1329

Query: 2447 KADQDSEAMKRLQAAGNAVKRASDNLVR 2474
            KAD  S AM+RLQAAGNAVKRAS+ LVR
Sbjct: 1330 KADPGSVAMQRLQAAGNAVKRASEALVR 1413

 Score = 58.9 bits (141), Expect(2) = e-121,   Method: Compositional matrix adjust.
 Identities = 29/38 (76%), Positives = 30/38 (78%)
 Frame = +2

Query: 2005 TLNAENGETFADHRENILKTAKALVEDTKLLVSGAAST 2042
            TLN E  ETFAD RENILKTAKALVEDTK LV+G   T
Sbjct: 2    TLNPEGDETFADQRENILKTAKALVEDTKTLVAGPPPT 115

 Score = 32.0 bits (71), Expect = 2.9,   Method: Compositional matrix adjust.
 Identities = 25/67 (37%), Positives = 37/67 (55%), Gaps = 1/67 (1%)
 Frame = +1

Query: 1481 QNLVDPGSSPSQ-VLSAATIVAKHTSALCNACRIASSKTANPVAKRHFVQSAKEVANSTA 1539
            ++ VD     SQ ++SAA +VA  T +LC A   A++      ++   + SAKEVA STA
Sbjct: 1135 RHAVDEDGQWSQGLISAARMVAAATHSLCEA---ANAMVQGHASEEKLIASAKEVAGSTA 1305

Query: 1540 NLVKTIK 1546
             L+   K
Sbjct: 1306 QLLMACK 1326
>30501
          Length = 638

 Score = 77.4 bits (189), Expect = 7e-14,   Method: Compositional matrix adjust.
 Identities = 53/143 (37%), Positives = 84/143 (58%), Gaps = 5/143 (3%)
 Frame = -1

Query: 2332 AKPKQADETLDFE--EQILEXXXXXXXXXXXLVKSASAAQRELVAQGKVGSIPANA--AD 2387
            +K ++ D  +  E  E+ILE           L+  + A Q+E+V+  K G+  AN     
Sbjct: 503  SKSRENDNKIKLEVNEKILEACTSLMECIKILILKSRALQKEIVSSQK-GNASANEFYKR 327

Query: 2388 DGQWSQGLISAARMVAAATSSLCEAANASVQGHASEE-KLISSAKQVAASTAQLLVACKV 2446
            + QWS GLISA++ VA A + L EAAN +V   + +  +LI +A+++AA T QL++A KV
Sbjct: 326  NSQWSDGLISASKSVAKAANYLVEAANNAVNSDSXQNFELIVAAQEIAACTVQLVIASKV 147

Query: 2447 KADQDSEAMKRLQAAGNAVKRAS 2469
            KA+++SE +  L AA   V +A+
Sbjct: 146  KANRNSENLTNLTAASRNVTKAT 78
>08616
          Length = 2833

 Score = 64.7 bits (156), Expect = 5e-10,   Method: Compositional matrix adjust.
 Identities = 40/134 (29%), Positives = 71/134 (52%), Gaps = 2/134 (1%)
 Frame = +2

Query: 273  IKQRGAEKRIFQEHKNCGEMSEIEAKVKYVKLARSLRTYGVSFFLVKEKMKGKNKLVPRL 332
            IK +   +RI + H N  EMS +EAK+ Y+K  +SL  +G+++F    ++K  N     L
Sbjct: 1025 IKSKAIVQRIMEAHANVREMSLMEAKMAYIKAWQSLPEFGITYF----RIKMANSKKEEL 1192

Query: 333  LGITKDSVMRVDEKTKEVLQEWPLTTVKRWAASP--KSFTLDFGEYQESYYSVQTTEGEQ 390
            LG+  + V+R+D  T + ++ W    ++ W  +   +S  LDF E Q+  +S      + 
Sbjct: 1193 LGVASNRVIRMDLNTGDSIKTWRYNLLQTWHVNWENESVILDF-EDQKVTFSPLECSCKT 1369

Query: 391  ISQLIAGYIDIILK 404
              + I GYI + ++
Sbjct: 1370 AHEFIGGYIFLSMR 1411

 Score = 52.4 bits (124), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 29/79 (36%), Positives = 48/79 (60%), Gaps = 3/79 (3%)
 Frame = +2

Query: 175 WLDHSRTFREQGVDENETLLLRRKFF-YSDQNVDSRDPVQLNLLYVQARDDILNGSHPVS 233
           WLD SR+  EQGV EN+ ++L+ KF+ + D N    DP+++N +Y QA+  +++     +
Sbjct: 188 WLDSSRSLMEQGVQENDFIMLKFKFYNFYDLN-PKYDPIRINQIYEQAKWALISEEIDCT 364

Query: 234 FEKACEFGG--FQAQIQFG 250
            E+   F    FQ+Q+Q G
Sbjct: 365 EEEMMVFAALQFQSQLQSG 421
>17332
          Length = 473

 Score = 48.9 bits (115), Expect = 2e-05,   Method: Composition-based stats.
 Identities = 30/116 (25%), Positives = 54/116 (46%), Gaps = 2/116 (1%)
 Frame = +2

Query: 174 NWLDHSRTFREQ--GVDENETLLLRRKFFYSDQNVDSRDPVQLNLLYVQARDDILNGSHP 231
           +WLD +++   Q  G      L    KF+ +D     R+ +   L ++Q + DIL G  P
Sbjct: 137 HWLDGNKSLSSQLKGCQTPHKLYFGVKFYAADP-CKLREEITRYLFFLQVKQDILQGRLP 313

Query: 232 VSFEKACEFGGFQAQIQFGPHVEHKHKPGFLDLKEFLPKEYIKQRGAEKRIFQEHK 287
           V+F++A E   +  Q + G     +H  G++    F+P +       E+R+   H+
Sbjct: 314 VTFDEASELCAYAVQSELGDFDPRQHTDGYVSEFCFIPNQ---TEELERRVAGLHR 472
>17228
          Length = 487

 Score = 39.7 bits (91), Expect = 0.015,   Method: Composition-based stats.
 Identities = 29/109 (26%), Positives = 52/109 (47%), Gaps = 4/109 (3%)
 Frame = +3

Query: 218 YVQARDDILNGSHPVSFEKACEFGGFQAQIQFGPHVEHKHKPGFLDLK-EFLPKEYIKQ- 275
           + Q   + L G H V+ E+A +      +++F     H  K  F D+    LP+ + +  
Sbjct: 132 FPQEVPNFLRGYHKVTGEEAVKMAALLYRVRFSQDATHFTK--FSDIAPAILPRGFPETG 305

Query: 276 --RGAEKRIFQEHKNCGEMSEIEAKVKYVKLARSLRTYGVSFFLVKEKM 322
                +K +  E+KN    S    + +++++A S  TYG  FF VK++M
Sbjct: 306 LLDDVKKAVEAEYKNSTGSSPDSVRERFLQMAVSWPTYGCVFFEVKQRM 452
>30680
          Length = 715

 Score = 30.8 bits (68), Expect = 6.7,   Method: Compositional matrix adjust.
 Identities = 16/48 (33%), Positives = 29/48 (60%)
 Frame = -1

Query: 1145 NDPEAAHAMLDSARDVMEGSAMLIQEAKQALIAPGDTESQQRLAQVAK 1192
            + P+AAH++L +AR++ E      QEA  A+  P D  +Q+R+ +  +
Sbjct: 151  DPPQAAHSLLVAAREI-ESYVPCTQEADDAIETPEDAVTQERVPETKR 11
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|124286826|ref|NP_659115.3| eukaryotic translation
termination factor 1 [Mus musculus]
         (437 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

01549                                                                 415   e-120
33693                                                                 175   7e-48
17669                                                                  99   4e-21
32244                                                                  29   4.0  
25312                                                                  29   4.0  
00673                                                                  29   4.3  
08223                                                                  28   5.6  
01195                                                                  28   7.8  
18020                                                                  28   9.2  
>01549
          Length = 2495

 Score =  415 bits (1067), Expect(2) = e-120,   Method: Compositional matrix adjust.
 Identities = 199/247 (80%), Positives = 226/247 (91%), Gaps = 1/247 (0%)
 Frame = +3

Query: 178 KKHGRGGQSALRFARLRME-KRHNYVRKVAETAVQLFISGDKVNVAGLVLAGSADFKTEL 236
           KKHGRGGQSALRFARLRME   +NYVRKVAE AVQLFI+ DK N++GLVLAGSADFKTEL
Sbjct: 39  KKHGRGGQSALRFARLRME*TYYNYVRKVAEVAVQLFITNDKPNISGLVLAGSADFKTEL 218

Query: 237 SQSDMFDQRLQSKVLKLVDISYGGENGFNQAIELSTEVLSNVKFIQEKKLIGRYFDEISQ 296
           SQSDMFD RLQ K++K+VD+SYGGENGFNQAIEL++E L+NVKFIQEKKLIGRYFDEISQ
Sbjct: 219 SQSDMFDPRLQGKIIKIVDVSYGGENGFNQAIELASESLANVKFIQEKKLIGRYFDEISQ 398

Query: 297 DTGKYCFGVEDTLKALEMGAVEILIVYENLDIMRYVLHCQGTEEEKILYLTPEQEKDKSH 356
           DTGKYCFGV+DTL+ALEMGAV+ LIV+EN+DI R+VL    T+EE+IL+L PEQEKDK+H
Sbjct: 399 DTGKYCFGVDDTLRALEMGAVDTLIVWENMDIQRFVLKNHTTDEERILHLGPEQEKDKTH 578

Query: 357 FTDKETGQEHELIESMPLLEWFANNYKKFGATLEIVTDKSQEGSQFVKGFGGIGGILRYR 416
           FTDK+TG E EL+E MPLLEWFANNYK FGATLEI+TD+SQEG+QFVKGFGGIGGILRY+
Sbjct: 579 FTDKDTGVEMELMEQMPLLEWFANNYKNFGATLEIITDRSQEGAQFVKGFGGIGGILRYQ 758

Query: 417 VDFQGME 423
           VDFQ ME
Sbjct: 759 VDFQMME 779

 Score = 34.3 bits (77), Expect(2) = e-120,   Method: Compositional matrix adjust.
 Identities = 14/14 (100%), Positives = 14/14 (100%)
 Frame = +1

Query: 165 TREVLHKFTVDLPK 178
           TREVLHKFTVDLPK
Sbjct: 1   TREVLHKFTVDLPK 42
>33693
          Length = 627

 Score =  175 bits (443), Expect(2) = 7e-48,   Method: Compositional matrix adjust.
 Identities = 84/89 (94%), Positives = 88/89 (98%)
 Frame = -3

Query: 18  KKLIKSLEAARGNGTSMISLIIPPKDQISRVAKMLADEFGTASNIKSRVNRLSVLGAITS 77
           +KLIKSLEAARGNGTSMISLIIPPKDQI+RV KMLADEFGTASNIKSRVNRLSVLGAITS
Sbjct: 268 QKLIKSLEAARGNGTSMISLIIPPKDQIARVNKMLADEFGTASNIKSRVNRLSVLGAITS 89

Query: 78  VQQRLKLYNKVPPNGLVVYCGTIVTEEGK 106
           VQQRLKLYNKVPPNGLV+YCGTI+TEEGK
Sbjct: 88  VQQRLKLYNKVPPNGLVIYCGTIITEEGK 2

 Score = 33.9 bits (76), Expect(2) = 7e-48,   Method: Compositional matrix adjust.
 Identities = 15/23 (65%), Positives = 19/23 (82%)
 Frame = -1

Query: 3   DDPSAADRNVEIWKIKKLIKSLE 25
           D  S+ADRNVEIWKIK L ++L+
Sbjct: 312 DGESSADRNVEIWKIKNLSRALK 244
>17669
          Length = 467

 Score = 98.6 bits (244), Expect = 4e-21,   Method: Compositional matrix adjust.
 Identities = 46/71 (64%), Positives = 56/71 (78%)
 Frame = +1

Query: 367 ELIESMPLLEWFANNYKKFGATLEIVTDKSQEGSQFVKGFGGIGGILRYRVDFQGMEYQG 426
           ELIES PLLEW ANNYK FGATLEI+TDKSQEGSQFV+GFGGIGGILRY++    + Y  
Sbjct: 1   ELIESQPLLEWLANNYKIFGATLEIITDKSQEGSQFVRGFGGIGGILRYKIS---LTYTA 171

Query: 427 GDDEFFDLDDY 437
            ++ +  + D+
Sbjct: 172 DEEGYHPVGDH 204
>32244
          Length = 751

 Score = 28.9 bits (63), Expect = 4.0,   Method: Compositional matrix adjust.
 Identities = 19/74 (25%), Positives = 37/74 (50%), Gaps = 1/74 (1%)
 Frame = -1

Query: 270 LSTEVLSNVKFIQEKKLIGRYFDEISQDTGKYCFGVEDTLKALEMGAVEILIVYEN-LDI 328
           L+   +   ++ QE+K   R+   + Q    Y        + L +   E+ ++Y++ ++I
Sbjct: 505 LNMRYMKQCQYHQERK---RFISRLCQYHALY--------EXLSITPGEVNVLYQDFVNI 359

Query: 329 MRYVLHCQGTEEEK 342
           MRY+ HCQ  +E K
Sbjct: 358 MRYMKHCQ*RQERK 317
>25312
          Length = 655

 Score = 28.9 bits (63), Expect = 4.0,   Method: Compositional matrix adjust.
 Identities = 12/34 (35%), Positives = 19/34 (55%)
 Frame = +3

Query: 297 DTGKYCFGVEDTLKALEMGAVEILIVYENLDIMR 330
            +GKY  G + TLK L  G  +++I+  N   +R
Sbjct: 255 KSGKYFLGYKQTLKTLRQGKAKLVIIANNTPPLR 356
>00673
          Length = 3471

 Score = 28.9 bits (63), Expect = 4.3,   Method: Compositional matrix adjust.
 Identities = 16/41 (39%), Positives = 20/41 (48%)
 Frame = +2

Query: 62  IKSRVNRLSVLGAITSVQQRLKLYNKVPPNGLVVYCGTIVT 102
           +K   N  S L AIT   +   LYNK PP      C ++VT
Sbjct: 5   VKKTDNIYSTLHAITCYHRIFSLYNKTPPP-----CSSLVT 112
>08223
          Length = 507

 Score = 28.5 bits (62), Expect = 5.6,   Method: Compositional matrix adjust.
 Identities = 12/34 (35%), Positives = 19/34 (55%)
 Frame = +1

Query: 297 DTGKYCFGVEDTLKALEMGAVEILIVYENLDIMR 330
            +GKY  G + TLK L  G  +++I+  N   +R
Sbjct: 160 KSGKYFLGYKQTLKTLRQGKAKLVIIANNTPPLR 261
>01195
          Length = 2128

 Score = 28.1 bits (61), Expect = 7.8,   Method: Compositional matrix adjust.
 Identities = 12/37 (32%), Positives = 20/37 (54%)
 Frame = -2

Query: 294 ISQDTGKYCFGVEDTLKALEMGAVEILIVYENLDIMR 330
           +   +GKY  G + TLK L  G  +++I+  N   +R
Sbjct: 753 LVMKSGKYFLGYKQTLKTLRQGKAKLVIIANNTPPLR 643
>18020
          Length = 497

 Score = 27.7 bits (60), Expect = 9.2,   Method: Compositional matrix adjust.
 Identities = 11/16 (68%), Positives = 12/16 (75%)
 Frame = -2

Query: 331 YVLHCQGTEEEKILYL 346
           Y LHC  TE EK+LYL
Sbjct: 481 YSLHCIATEREKLLYL 434
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|17975508|ref|NP_083079.1| glucan (1,4-alpha-),
branching enzyme 1 [Mus musculus]
         (702 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

26122                                                                 221   e-120
24316                                                                  30   2.9  
>26122
          Length = 907

 Score =  221 bits (563), Expect(3) = e-120,   Method: Compositional matrix adjust.
 Identities = 106/154 (68%), Positives = 125/154 (81%), Gaps = 1/154 (0%)
 Frame = +1

Query: 381 FGLQVDEDALIYLMLANHLAHTLYPD-SITIAEDVSGMPALCSPTSQGGGGFDYRLAMAI 439
           FGL  D +A  YL LAN++ H LYPD  +T++EDVSGMP L  P  +GG GFDYRLAM +
Sbjct: 445 FGLNTDTEAFNYLTLANYMLHGLYPDFMVTVSEDVSGMPTLGRPVEEGGCGFDYRLAMGL 624

Query: 440 PDKWIQLLKEFKDEDWNMGNIVYTLTNRRYLEKCVAYAESHDQALVGDKTLAFWLMDAEM 499
           PD WI+LLK+  DEDWN+ NIV+TLTNRR+ E C+AY ESHDQALVGDKT+AFWLMD EM
Sbjct: 625 PDMWIKLLKKTADEDWNIDNIVHTLTNRRWSEPCIAYTESHDQALVGDKTIAFWLMDKEM 804

Query: 500 YTNMSVLAPFTPVIDRGIQLHKMIRLITHGLGGE 533
           YT+MSV+AP + VIDRG+ LHKMIRLIT GLGGE
Sbjct: 805 YTHMSVMAPPSLVIDRGMALHKMIRLITIGLGGE 906

 Score =  174 bits (441), Expect(3) = e-120,   Method: Compositional matrix adjust.
 Identities = 81/99 (81%), Positives = 88/99 (88%)
 Frame = +3

Query: 241 MEHAYYASFGYQITSFFAASSRYGTPEELKELVDTAHSMGIVVLLDVVHSHASKNSEDGL 300
           MEHAYYA FGYQ+TSFFAASSRYG+PE+LKELVDTAH+ G+ VLLDVVHSHASKN  DGL
Sbjct: 27  MEHAYYACFGYQVTSFFAASSRYGSPEDLKELVDTAHAHGVTVLLDVVHSHASKNVVDGL 206

Query: 301 NMFDGTDSCYFHSGPRGTHDLWDSRLFIYSSWEVLRFLL 339
           N FDGT+SCYFH G RGTHDLWDSRLF Y+SWEVLRF  
Sbjct: 207 NQFDGTNSCYFHDGGRGTHDLWDSRLFNYTSWEVLRFCC 323

 Score = 75.9 bits (185), Expect(3) = e-120,   Method: Compositional matrix adjust.
 Identities = 33/44 (75%), Positives = 39/44 (88%)
 Frame = +2

Query: 337 FLLSNIRWWLEEYCFDGFRFDGVTSMLYHHHGMGQGFSGDYNEY 380
           FLLSN+R W++EY FDGFRFDGVTSM+YH HGMG GF+G Y+EY
Sbjct: 314 FLLSNLRMWVDEYGFDGFRFDGVTSMVYHTHGMGHGFTGHYDEY 445
>24316
          Length = 1038

 Score = 30.4 bits (67), Expect = 2.9,   Method: Compositional matrix adjust.
 Identities = 11/35 (31%), Positives = 23/35 (65%)
 Frame = +3

Query: 207 SSHEGKIASYKHFTSNVLPRIKDLGYNCIQLMAIM 241
           ++HE +I ++KH  SNVL  + ++  NC +++  +
Sbjct: 411 NTHENRIINHKH*VSNVLRLLSNVSTNCQRILIFL 515
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|25141235|ref|NP_036138.1| DEAD (Asp-Glu-Ala-Asp) box
polypeptide 3, Y-linked [Mus musculus]
         (658 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

01517                                                                 427   e-120
00621                                                                 280   1e-75
17544                                                                 243   2e-64
09327                                                                 211   5e-55
04883                                                                 211   1e-54
01062                                                                 196   2e-50
09316                                                                 167   2e-41
33025                                                                 162   4e-40
02054                                                                  91   6e-32
00739                                                                 130   2e-30
00162                                                                 116   5e-30
02498                                                                  80   5e-29
07310                                                                 121   1e-27
22006                                                                 102   6e-22
14337                                                                 100   2e-21
19525                                                                  96   5e-20
30136                                                                  93   3e-19
19640                                                                  89   3e-18
34295                                                                  84   2e-16
12995                                                                  80   2e-15
19172                                                                  80   3e-15
00617                                                                  75   1e-13
11160                                                                  65   2e-12
17708                                                                  71   2e-12
39583                                                                  70   3e-12
11624                                                                  70   3e-12
19151                                                                  63   5e-10
12121                                                                  62   8e-10
31220                                                                  56   5e-08
10649                                                                  54   2e-07
03381                                                                  54   3e-07
08036                                                                  53   5e-07
31899                                                                  52   1e-06
11423                                                                  44   1e-04
33083                                                                  44   2e-04
06438                                                                  44   2e-04
34134                                                                  41   0.001
01821                                                                  36   0.061
01797                                                                  35   0.070
33543                                                                  33   0.47 
>01517
          Length = 2605

 Score =  427 bits (1097), Expect = e-120,   Method: Compositional matrix adjust.
 Identities = 208/252 (82%), Positives = 227/252 (90%), Gaps = 2/252 (0%)
 Frame = +2

Query: 327 VDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPK 386
           VDMMERGKIG+D C YLVLDEADRMLDMGFEPQIRRIVE+DTMPP G R T+MFSATFPK
Sbjct: 2   VDMMERGKIGMDHCNYLVLDEADRMLDMGFEPQIRRIVEKDTMPPTGQRQTLMFSATFPK 181

Query: 387 EIQMLARDFLDEYIFLAVGRVGSTSENITQKVVWVEELDKRSFLLDLLNA--TGKDSLTL 444
           EIQ+LARDFLD YIFLAVGRVGSTSENITQKVVWVEE +KRSFLLDLL A  TG +SLTL
Sbjct: 182 EIQLLARDFLDNYIFLAVGRVGSTSENITQKVVWVEEPEKRSFLLDLLMASGTGPESLTL 361

Query: 445 VFVETKKGADSLENFLFQERYACTSIHGDRSQKDREEALHQFRSGRKPILVATAVAARGL 504
           VFVETKKGADSLE FL  E Y  TSIHGDRSQ++RE+AL  F++G +PILVATAVAARGL
Sbjct: 362 VFVETKKGADSLEQFLMYENYPATSIHGDRSQREREDALRVFKNGDRPILVATAVAARGL 541

Query: 505 DISNVKHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNERNLNITKDLLDLLVEAKQ 564
           DI NV+HVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFN++N NI +D+LDLL EA Q
Sbjct: 542 DIPNVRHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNDKNRNIARDMLDLLTEANQ 721

Query: 565 EVPSWLESMAYE 576
           EVPSWLES+AY+
Sbjct: 722 EVPSWLESLAYD 757
>00621
          Length = 2263

 Score =  280 bits (717), Expect = 1e-75,   Method: Compositional matrix adjust.
 Identities = 153/385 (39%), Positives = 227/385 (58%), Gaps = 21/385 (5%)
 Frame = +1

Query: 199 YTRPTPVQKHAIPIIKEKRDLMACAQTGSGKTAAFLLPILSQIYTDGPGEALKAMKENGR 258
           Y  PTP+Q  AIPI  + RD++  A+TGSGKTAAFL+P+L  I         +++ +  R
Sbjct: 313 YKEPTPIQMQAIPIGLQNRDIIGVAETGSGKTAAFLIPLLVWI---------QSLPKIER 465

Query: 259 YGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADTVQQIRDLERGCHL 318
                Q P +++LAPTRELA QI EE RKF     +R   V GG    +Q   L++GC +
Sbjct: 466 LEDADQGPYAVILAPTRELAQQIEEETRKFGEGLGIRVVSVIGGISREEQGFKLQQGCEV 645

Query: 319 LVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRIVE------------- 365
           ++ATPGR++D++E   + L+ C Y+V+DEADRM++MGFEP++R+I++             
Sbjct: 646 VIATPGRMIDVLENRYLVLNQCTYVVMDEADRMINMGFEPEVRKILDYLPVSNQKPDNDD 825

Query: 366 --------QDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQK 417
                   Q+       R T+MF+AT P +++ LAR FL     + +G VG   E + Q 
Sbjct: 826 AEDDLKMLQNFKSKHKYRQTVMFTATMPPQVERLARTFLRRPTVVYIGNVGKPVERVEQI 1005

Query: 418 VVWVEELDKRSFLLDLLNATGKDSLTLVFVETKKGADSLENFLFQERYACTSIHGDRSQK 477
           V  + E +KR  L+++LNA G D   ++FV  KKGAD L   L +  +  T++HG + Q+
Sbjct: 1006VYMLTESEKRKKLIEVLNA-GVDPPIIIFVNQKKGADVLAKSLEKMGFNATTLHGGKGQE 1182

Query: 478 DREEALHQFRSGRKPILVATAVAARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVGNL 537
            RE AL   + G K I+VAT VA RG+DI +V  V+N+D+   IE+Y HRIGRTGR G  
Sbjct: 1183QREYALASLKGGAKDIMVATDVAGRGIDIKDVSLVLNYDMARTIEDYTHRIGRTGRAGKE 1362

Query: 538 GLATSFFNERNLNITKDLLDLLVEA 562
           G + +F  + +  +  DL  L++ +
Sbjct: 1363GTSITFLTKEDSMVFYDLKQLMLSS 1437
>17544
          Length = 1047

 Score =  243 bits (620), Expect = 2e-64,   Method: Compositional matrix adjust.
 Identities = 117/181 (64%), Positives = 144/181 (79%), Gaps = 1/181 (0%)
 Frame = +2

Query: 138 PLPPSERLEQELFSGGNTGINFEKYDDIPVEATGNNCPPHIENFSDXXXXXXXXXXXXLT 197
           PLP + RLEQELF G NTGINF+KY+DIPVEATG++ PPHI +F +            L+
Sbjct: 509 PLPQNSRLEQELFGGNNTGINFDKYEDIPVEATGDSPPPHINSFEECTLGEIIRNNIVLS 688

Query: 198 RYTRPTPVQKHAIPIIKEKRDLMACAQTGSGKTAAFLLPILSQIYTDGPGEALKAMKENG 257
           +Y +PTPVQK A+PI+  KRDLMACAQTGSGKTAAFLLPIL+Q+Y +GP    +A+++N 
Sbjct: 689 KYNKPTPVQKFALPIVLGKRDLMACAQTGSGKTAAFLLPILNQVYENGP--TPEALQQNQ 862

Query: 258 RYG-RRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADTVQQIRDLERGC 316
             G RRK YPI+L+LAPTRELA QIY+EARKF+YRSR+RPCVVYGGAD   Q+RDL++GC
Sbjct: 863 SRGYRRKMYPIALILAPTRELASQIYDEARKFAYRSRLRPCVVYGGADIGAQMRDLDKGC 1042

Query: 317 H 317
           H
Sbjct: 1043H 1045
>09327
          Length = 1087

 Score =  211 bits (538), Expect = 5e-55,   Method: Compositional matrix adjust.
 Identities = 115/238 (48%), Positives = 161/238 (67%), Gaps = 3/238 (1%)
 Frame = +2

Query: 270 VLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADTVQQIRDLERGCHLLVATPGRLVDM 329
           +L PTRELA Q+ E A +F + SRVR   VYGGA    Q+R+L+RG  + +ATPGRL+D 
Sbjct: 20  LLVPTRELAQQVQEVAVEFGHSSRVRSVCVYGGAQRGPQLRELDRGAEICIATPGRLIDF 199

Query: 330 MERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQ 389
           +E  +  L  C YLVLDEADRMLDMGFEPQIR+IVEQ  + P   R T+M+SAT+PKE++
Sbjct: 200 LESNRTNLRRCTYLVLDEADRMLDMGFEPQIRKIVEQ--IRPD--RQTLMWSATWPKEVR 367

Query: 390 MLARDFLDEYIFLAVGRVGSTS-ENITQKVVWVEELDKRSFLLDLLNAT--GKDSLTLVF 446
            LA DF+ EY  + +G +  T+  NI Q +    + +K   L+ LLN     K++ TL+F
Sbjct: 368 KLAEDFIMEYTQINIGALQLTANHNILQIIDVCMDHEKEEKLVKLLNEIMQEKENRTLIF 547

Query: 447 VETKKGADSLENFLFQERYACTSIHGDRSQKDREEALHQFRSGRKPILVATAVAARGL 504
           VETK+  D +   + ++ +    IHGD+SQ++R+  L+ FR+GR P+L+AT VA+RGL
Sbjct: 548 VETKRKCDDIHRRMKRDGWPVLCIHGDKSQQERDWVLNDFRNGRCPVLLATDVASRGL 721
>04883
          Length = 1155

 Score =  211 bits (536), Expect = 1e-54,   Method: Compositional matrix adjust.
 Identities = 117/270 (43%), Positives = 157/270 (58%), Gaps = 1/270 (0%)
 Frame = +3

Query: 167 VEATGNNCPPHIENFSDXXXXXXXXXXXXLTRYTRPTPVQKHAIPIIKEKRDLMACAQTG 226
           +  +G   P  I  F++               +T PTP+Q  + P+    +DL+  AQTG
Sbjct: 324 ISVSGKFVPNPILTFTEVNFPDYVMNQVRRNSWTAPTPIQSQSWPVAMAGKDLVGIAQTG 503

Query: 227 SGKTAAFLLPILSQIYTDGPGEALKAMKENGRYGRRKQYPISLVLAPTRELAVQIYEEAR 286
           SGKT AF+LP +  I              +  Y  R   PI L L PTRELA Q+ E A+
Sbjct: 504 SGKTLAFMLPAIVHI-------------NHQAYLERGDGPIVLALVPTRELAQQVQEVAQ 644

Query: 287 KFSYRSRVRPCVVYGGADTVQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLD 346
           +F + SRVR   VYGGA    Q+RDLERG  + +ATPGRL+D +E  +  L  C YLVLD
Sbjct: 645 EFGHASRVRSVCVYGGAPRGPQLRDLERGAEICIATPGRLIDFLESNRTNLRRCTYLVLD 824

Query: 347 EADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGR 406
           EADRMLDMGFEPQIR+I+EQ     +  R T+M+SAT+PKE++ LA DF+DEY+ + +G 
Sbjct: 825 EADRMLDMGFEPQIRKIIEQI----RPDRQTLMWSATWPKEVRKLAEDFIDEYVQVNIGA 992

Query: 407 VGSTS-ENITQKVVWVEELDKRSFLLDLLN 435
           +  T+  NI Q +    E +K   L+ LLN
Sbjct: 993 LELTANHNILQIIDVCMEHEKEDKLVKLLN 1082
>01062
          Length = 2138

 Score =  196 bits (498), Expect = 2e-50,   Method: Compositional matrix adjust.
 Identities = 123/361 (34%), Positives = 192/361 (53%), Gaps = 4/361 (1%)
 Frame = -3

Query: 199  YTRPTPVQKHAIPIIKEKRDLMACAQTGSGKTAAFLLPILSQIYTDGPGEALKAMKENGR 258
            + +P+ +Q+ A+  I + RD++A AQ+G+GKTA F + +L  +           ++E   
Sbjct: 2019 FEKPSAIQQRAVKPIVKGRDVIAQAQSGTGKTATFSISVLQCLDIQ--------LRETQ- 1867

Query: 259  YGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADTVQQIRDLERGCHL 318
                     +L+L+PTRELA QI +          V+     GG +  + IR L+ G H+
Sbjct: 1866 ---------ALILSPTRELATQIQKVMLALGDYMNVQCHSCIGGTNIGEDIRKLDYGQHI 1714

Query: 319  LVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTM 378
            +  TPGR+ DM++R  +     K ++LDEAD ML+ GF+ QI  +     +PP      +
Sbjct: 1713 VSGTPGRVFDMIKRRNLRTRSIKMMILDEADEMLNKGFKEQIYDVYRY--LPPAT--QVI 1546

Query: 379  MFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVVWVE----ELDKRSFLLDLL 434
            + SAT P EI  +   F+ + I + V R   T E I Q  V VE    + D    L D L
Sbjct: 1545 LISATLPHEILEMTNKFMTDPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTL 1366

Query: 435  NATGKDSLTLVFVETKKGADSLENFLFQERYACTSIHGDRSQKDREEALHQFRSGRKPIL 494
              T      ++F  TK+  D L   + +  +  +S+HGD  QK+RE  +  FR+G   +L
Sbjct: 1365 TITQ----AVIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKEREAIMKVFRAGDSRVL 1198

Query: 495  VATAVAARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNERNLNITKD 554
            + T V ARG+D+  V  VIN+DLP++ E Y+HRIGR+GR G  G+A +F    ++ I +D
Sbjct: 1197 ITTDVWARGIDVQQVSLVINYDLPNNRELYIHRIGRSGRFGRKGVAINFVKNDDIRILRD 1018

Query: 555  L 555
            +
Sbjct: 1017 I 1015
>09316
          Length = 2312

 Score =  167 bits (422), Expect = 2e-41,   Method: Compositional matrix adjust.
 Identities = 111/354 (31%), Positives = 180/354 (50%), Gaps = 4/354 (1%)
 Frame = +2

Query: 199  YTRPTPVQKHAIPIIKEKRDLMACAQTGSGKTAAFLLPILSQIY-TDGPGEALKAMKENG 257
            +  P+ VQ   IP      D++  A++G GKTA F+L  L Q+   DG    L       
Sbjct: 905  FEHPSEVQHECIPQAILSMDVLCQAKSGMGKTAVFVLATLQQLEPVDGQVSVL------- 1063

Query: 258  RYGRRKQYPISLVLAPTRELAVQIYEEARKFS-YRSRVRPCVVYGGADTVQQIRDLERGC 316
                        V+A TRELA QI +E  +FS Y + V+  V +GG    +    L + C
Sbjct: 1064 ------------VMAHTRELAFQISKEYERFSKYMNNVKIAVFFGGMSVKKDEEVLSKNC 1207

Query: 317  -HLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVR 375
             H++V TPGRL  + +   + L   K+ +LDE D+ML    +  +RR V++        +
Sbjct: 1208 PHIVVGTPGRLHALAKANNLNLKKIKHFILDECDKMLA---DLDMRRDVQEIFRLTPHEK 1378

Query: 376  HTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGS-TSENITQKVVWVEELDKRSFLLDLL 434
              MMFSAT  KEI+ + + F+ + + + V      T   + Q    +++ +K   L +LL
Sbjct: 1379 QVMMFSATLSKEIRPICKKFMQDPMEVYVDDDSKLTLHGLQQHYCKLKDNEKNRKLFELL 1558

Query: 435  NATGKDSLTLVFVETKKGADSLENFLFQERYACTSIHGDRSQKDREEALHQFRSGRKPIL 494
            +    + + ++FV++     +L   L ++ +   +IH   +Q++R     QF+  +K IL
Sbjct: 1559 DVLEFNQV-IIFVKSVPRCMALSQLLLEQNFPAIAIHRQMTQEERLSRYQQFKDFQKRIL 1735

Query: 495  VATAVAARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNERN 548
            VAT +  RG+DI  V  V N+D+P D + Y+HR+ R GR G  GLA +F ++ N
Sbjct: 1736 VATNLFGRGMDIERVNIVFNYDMPEDSDTYLHRVARAGRFGTKGLAITFVSDEN 1897
>33025
          Length = 558

 Score =  162 bits (410), Expect = 4e-40,   Method: Compositional matrix adjust.
 Identities = 81/158 (51%), Positives = 107/158 (67%)
 Frame = +3

Query: 281 IYEEARKFSYRSRVRPCVVYGGADTVQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFC 340
           IY EA KFS  + V P VVYG  D   Q   + +G +L+V TPGRL+D +    I L  C
Sbjct: 3   IYGEAYKFSRGTDVHPSVVYGATDRRYQKSRIMKGANLVVGTPGRLLDFIGDQTISLGKC 182

Query: 341 KYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYI 400
           +YL+LDEADRMLDMGFEP+IR++V+   MPPK  R T+MFSATF ++IQ LA DFL++Y+
Sbjct: 183 QYLILDEADRMLDMGFEPEIRKLVDTHGMPPKTQRQTLMFSATFKEDIQRLAGDFLNDYL 362

Query: 401 FLAVGRVGSTSENITQKVVWVEELDKRSFLLDLLNATG 438
           F+ VG VG    ++TQ  + V+ L KR  L ++LN  G
Sbjct: 363 FITVGIVGGACSDVTQTFLEVDRLQKRDHLCEILNEMG 476
>02054
          Length = 1110

 Score = 91.3 bits (225), Expect(2) = 6e-32,   Method: Compositional matrix adjust.
 Identities = 53/178 (29%), Positives = 96/178 (53%)
 Frame = -3

Query: 391 LARDFLDEYIFLAVGRVGSTSENITQKVVWVEELDKRSFLLDLLNATGKDSLTLVFVETK 450
           L R  L + + + V     T + + Q  +++    K ++L+ +LN    +S  +VF  T 
Sbjct: 784 LQRASLRDPVKVEVSNKYQTVDTLQQSYLFIPAKYKDAYLVSILNELAGNSF-MVFCSTC 608

Query: 451 KGADSLENFLFQERYACTSIHGDRSQKDREEALHQFRSGRKPILVATAVAARGLDISNVK 510
                +   L    +    +HG  SQ  R  +L++F+S  + IL+AT VA+RGLDI +V 
Sbjct: 607 ANTQRVALLLRNLGFTAIPLHGQMSQAKRLGSLNKFKSKDRSILIATDVASRGLDIPHVD 428

Query: 511 HVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNERNLNITKDLLDLLVEAKQEVPS 568
            V+N D+P+  ++Y+HR+GRT R G  G A +F ++ ++ + + +  L+ +   E P+
Sbjct: 427 VVLNLDIPTHSKDYMHRVGRTARAGRSGRAITFVSQYDVELYQRIEHLIGKKLSEYPT 254

 Score = 65.1 bits (157), Expect(2) = 6e-32,   Method: Compositional matrix adjust.
 Identities = 43/108 (39%), Positives = 66/108 (61%), Gaps = 1/108 (0%)
 Frame = -2

Query: 282  YEEARKFSYRSRVRPCVVYGGADTVQQIRDLERGCHLLVATPGRLVDMMERGK-IGLDFC 340
            +E+A  FS    VR  +V  G D   Q   L +  H+++ATPGRLVD +E  K   L   
Sbjct: 1085 WEKALAFS----VR*LLV--GIDMSTQALMLGKKPHIIIATPGRLVDHLENTKGFSLRAL 924

Query: 341  KYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEI 388
            K+LV+DEADR+LDM F+ ++ +I++   +P +  R+T +FSAT   ++
Sbjct: 923  KFLVMDEADRILDMNFQDEVDKILK--VIPRE--RNTYLFSATMTNKV 792
>00739
          Length = 1313

 Score =  130 bits (327), Expect = 2e-30,   Method: Compositional matrix adjust.
 Identities = 82/256 (32%), Positives = 139/256 (54%), Gaps = 4/256 (1%)
 Frame = +3

Query: 304 DTVQQIRDLERGCHLLVATPGRLVDMMER-GKIGLDFCKYLVLDEADRMLDMGFEPQIRR 362
           D ++Q +DL    H++++TPGRL D ++      L   K+LV+DEADR+LD  F  Q+  
Sbjct: 6   DMMKQGQDLAVKPHIVISTPGRLADHIDSCDTFSLKRVKFLVMDEADRLLDDNFGAQLEP 185

Query: 363 IVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVVWVE 422
           I+ +  +P    R T++FSAT    +  L    L++          +T + + +  V V 
Sbjct: 186 ILTR--LP--SARQTLLFSATLSPTVNALRDSVLNKPFVWIQQSERATVDELQEDYVLVP 353

Query: 423 ELDKRSFLLDLLNATGKD---SLTLVFVETKKGADSLENFLFQERYACTSIHGDRSQKDR 479
              K ++++ +L+   KD   S  ++F  T K A  L   L + +++C  +H    Q+ R
Sbjct: 354 ASMKDAYMVHILDHWLKDHPRSSLIIFTXTCKYAQILGMMLEKLQFSCAVLHSMIPQRFR 533

Query: 480 EEALHQFRSGRKPILVATAVAARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVGNLGL 539
             +L +F+S +  IL++T VA+RGLDI  V  +IN ++P+   +YVHR+GRT R G  G 
Sbjct: 534 LSSLSRFKSNQTRILISTDVASRGLDIPTVDLIINHNIPNRPRDYVHRVGRTARAGRCGQ 713

Query: 540 ATSFFNERNLNITKDL 555
           + S   E ++ + K +
Sbjct: 714 SISLVTEFDIKLIKSI 761
>00162
          Length = 2322

 Score =  116 bits (290), Expect(2) = 5e-30,   Method: Compositional matrix adjust.
 Identities = 86/271 (31%), Positives = 135/271 (49%), Gaps = 5/271 (1%)
 Frame = +3

Query: 268 SLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADTVQQIRDLERGCHLLVATPGRLV 327
           +L++ PTRELA QIYE   K          +V GG    ++   + +  ++++ T GRL+
Sbjct: 144 ALIITPTRELAFQIYEVLNKIRTFHDFSANLVIGGKFMWRETHLMGKT-NIVICTVGRLL 320

Query: 328 DMMERGK-IGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPK 386
             +E  +   +   K LVLDEADR++D  F   +  I+    +PP   R T++FSAT   
Sbjct: 321 HHLESTQAFDVSELKVLVLDEADRIMDSKFAQDMDSIMSH--LPP---RQTLLFSATQTM 485

Query: 387 EIQMLARDFLDEYIFLAVGRVGS--TSENITQKVVWVEELDKRSFLLDLLNATGKDSLTL 444
            ++ LAR  L +  +++V R     T   + Q  +  E  +K S L   L     + + +
Sbjct: 486 SVKTLARLSLKDPSYVSVDRHAEYVTPTGLEQSYIVCELHEKLSLLYSFLKNHPNNKI-M 662

Query: 445 VFVETKKGADSLENFLFQER--YACTSIHGDRSQKDREEALHQFRSGRKPILVATAVAAR 502
           VF++T K A  +   + +ER   +   +HG   Q  R +   +F   +  IL+ T +A R
Sbjct: 663 VFLQTCKQARYVHTVIKRERPGMSVLVLHGGIPQLRRLDIYREFCRKQHVILITTDLACR 842

Query: 503 GLDISNVKHVINFDLPSDIEEYVHRIGRTGR 533
           GLD   V  VI  D P D+  Y+HR GRT R
Sbjct: 843 GLDFPAVNWVIQLDCPVDVNTYIHRAGRTAR 935

 Score = 33.5 bits (75), Expect(2) = 5e-30,   Method: Compositional matrix adjust.
 Identities = 14/24 (58%), Positives = 19/24 (79%)
 Frame = +2

Query: 218 DLMACAQTGSGKTAAFLLPILSQI 241
           D++  A+TGSGKT AFL+PIL  +
Sbjct: 38  DVLGAAKTGSGKTLAFLIPILETL 109
>02498
          Length = 1955

 Score = 79.7 bits (195), Expect(2) = 5e-29,   Method: Compositional matrix adjust.
 Identities = 48/165 (29%), Positives = 88/165 (53%), Gaps = 9/165 (5%)
 Frame = +3

Query: 400 IFLAVGRVGSTSENITQKVVWVEELDKRSFLLDLLNATGKDSL--TLVFVETKKGADSLE 457
           + +++ R   + +NI Q  +     +++   + L N  G  S+  +++F   +  A  L 
Sbjct: 738 VIISLKREEESLDNIKQYYIDCNSQEEK--YVALCNIYGSISVGQSMIFCHKRSTAAWLA 911

Query: 458 NFLFQERYACTSIHGDRSQKDREEALHQFRSGRKPILVATAVAARGLDISNVKHVINFDL 517
             +  + +A   + G+ + + R   + +FR G++ +L+ T V+ARG+D+  V  V+NFDL
Sbjct: 912 ERMTADHHAVGLLTGELTIEQRAAIIKRFREGKEKVLITTNVSARGIDVEMVTVVVNFDL 1091

Query: 518 P------SDIEEYVHRIGRTGRVGNLGLATSFF-NERNLNITKDL 555
           P       D E Y+HRIGRTGR G  G+A +   N R++ I + +
Sbjct: 1092PVTQDWRPDCETYLHRIGRTGRFGKNGIAINMVDNSRSMAIMRSI 1226

 Score = 67.4 bits (163), Expect(2) = 5e-29,   Method: Compositional matrix adjust.
 Identities = 64/209 (30%), Positives = 102/209 (48%), Gaps = 11/209 (5%)
 Frame = +1

Query: 199 YTRPTPVQKHAIPII--KEKRDLMACAQTGSGKTAAFLLPILSQIYTDGPGEALKAMKEN 256
           +  P+ +Q+ A+PI+      +++A +Q+G+GKTAAF+L +LS                 
Sbjct: 193 FNAPSKIQETALPILLADPPVNMIAQSQSGTGKTAAFVLTMLS----------------- 321

Query: 257 GRYGRRKQYPISLVLAPTRELAVQIYEEARKFS-------YRSRVRPCVVYGGADTVQQI 309
            R    + +P  L LAPT ELA+QI E   K S        R  VR   V  G    +QI
Sbjct: 322 -RVDISQTFPQCLCLAPTYELALQIGEVIEKMSKHMTGLEIRYAVRGERVNRGEVLSEQI 498

Query: 310 RDLERGCHLLVATPGRLVDMMERGK-IGLDFCKYLVLDEADRMLDM-GFEPQIRRIVEQD 367
                    ++ TPG ++D   R K + L+  +  VLDEAD M+ M G + Q  RI ++ 
Sbjct: 499 ---------VIGTPGTVMDWSHRFKALPLEKLRVFVLDEADVMISMQGHQDQSTRIQKRL 651

Query: 368 TMPPKGVRHTMMFSATFPKEIQMLARDFL 396
           +    G +  ++FSAT+ + +   A+  +
Sbjct: 652 S---SGCQ-MLLFSATYDQVVMQFAQRII 726
>07310
          Length = 712

 Score =  121 bits (303), Expect = 1e-27,   Method: Compositional matrix adjust.
 Identities = 69/219 (31%), Positives = 119/219 (54%)
 Frame = +2

Query: 325 RLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATF 384
           R++D+M +  +  D C  LVLDEAD++L   F+  +  I+    +PP+  R  +++SATF
Sbjct: 2   RILDLMNKRLVKPDTCGILVLDEADKLLSQDFKGMLDNIIAH--LPPQ--RQILLYSATF 169

Query: 385 PKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVVWVEELDKRSFLLDLLNATGKDSLTL 444
           P  ++   + +L     + +     T + +TQ   +V+E  ++   L+ L +  + + ++
Sbjct: 170 PLSVEQFMKKYLKNPYEINLME-ELTLKGVTQYYAFVQE-KQKVHCLNTLFSKLQINQSI 343

Query: 445 VFVETKKGADSLENFLFQERYACTSIHGDRSQKDREEALHQFRSGRKPILVATAVAARGL 504
           +F  + +  + L   + +  Y+C  IH   +Q+ R    H FR G    LV + +  RG+
Sbjct: 344 IFCNSTQRVELLAKKITELGYSCYYIHAKMNQQHRNRVFHDFRQGLCRNLVCSDLFTRGI 523

Query: 505 DISNVKHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSF 543
           DI  V  VINFD P   E Y+HRIGR+GR G+LG+A + 
Sbjct: 524 DIQAVNVVINFDFPKHAETYLHRIGRSGRYGHLGVAINL 640
>22006
          Length = 3414

 Score =  102 bits (253), Expect = 6e-22,   Method: Compositional matrix adjust.
 Identities = 57/153 (37%), Positives = 88/153 (57%)
 Frame = +2

Query: 202  PTPVQKHAIPIIKEKRDLMACAQTGSGKTAAFLLPILSQIYTDGPGEALKAMKENGRYGR 261
            PTP+Q+  IP+I E +D++A A+TGSGKTAAFL+P+L +            +K +   G 
Sbjct: 3005 PTPIQRKTIPVIMEGKDMVAMARTGSGKTAAFLVPMLER------------LKMHSSKGA 3148

Query: 262  RKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADTVQQIRDLERGCHLLVA 321
            R     +L+L+PTRELA+Q  +  ++      +R  V+ GG     Q   L +   +++A
Sbjct: 3149 R-----ALILSPTRELALQTLKFTKELGKFLDLRAAVILGGDRMEDQFSALHQNPDIIIA 3313

Query: 322  TPGRLVDMMERGKIGLDFCKYLVLDEADRMLDM 354
            TPGRL+ ++   K  L    Y+V DEADR+ +M
Sbjct: 3314 TPGRLLHVLVEMKKSLKEVIYVVFDEADRLFEM 3412
>14337
          Length = 693

 Score =  100 bits (249), Expect = 2e-21,   Method: Compositional matrix adjust.
 Identities = 46/128 (35%), Positives = 77/128 (60%)
 Frame = +2

Query: 443 TLVFVETKKGADSLENFLFQERYACTSIHGDRSQKDREEALHQFRSGRKPILVATAVAAR 502
            LVFV++K+ A  L +    +++   +IH D+ Q +R+  +  F  GR  +LV T +  R
Sbjct: 65  VLVFVQSKQRAKELYSEFMFDKHKVDAIHADKPQAERDATVRAFTEGRVWVLVCTELMGR 244

Query: 503 GLDISNVKHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNERNLNITKDLLDLLVEA 562
           G+D   +  VIN+D P++   Y+HRIGRTGR G  G A +FF E+++   + + +++ EA
Sbjct: 245 GIDFKGINLVINYDFPTNAVSYIHRIGRTGRAGVPGRAITFFTEQDVTHLRSIANIIKEA 424

Query: 563 KQEVPSWL 570
             EVP ++
Sbjct: 425 GCEVPEYM 448
>19525
          Length = 585

 Score = 95.9 bits (237), Expect = 5e-20,   Method: Composition-based stats.
 Identities = 65/186 (34%), Positives = 99/186 (53%), Gaps = 4/186 (2%)
 Frame = +2

Query: 269 LVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADTVQQIRDLERGCHLLVATPGRLVD 328
           LVL PTRELAVQ+Y+  ++ S  +++  C+  GG D   Q   L     ++VATPGRL+D
Sbjct: 23  LVLVPTRELAVQVYQVGQQISQYTKISICLAAGGLDIKGQEAALRLCPDIVVATPGRLID 202

Query: 329 MMERG-KIGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKE 387
            +       +   + LVLDEADRMLD  F  Q+  I+          R TM+FSAT    
Sbjct: 203 HLHNAPNFTIAHVEILVLDEADRMLDEYFAAQMTEIIRMCNFQ----RQTMLFSATMSDA 370

Query: 388 IQMLARDFLDEYIFLAVGRVGSTSENITQKVVWV---EELDKRSFLLDLLNATGKDSLTL 444
           +Q LA   L E + + V +    +  + Q+ V +   +E D+ + +  L++ T  D   +
Sbjct: 371 VQDLASVSLKEAVKVFVNQNTDIALGLQQEFVRIRENKEGDREAIVSSLVSRTFCDK-CM 547

Query: 445 VFVETK 450
           VF++TK
Sbjct: 548 VFLQTK 565
>30136
          Length = 524

 Score = 93.2 bits (230), Expect = 3e-19,   Method: Composition-based stats.
 Identities = 51/124 (41%), Positives = 69/124 (55%)
 Frame = +2

Query: 199 YTRPTPVQKHAIPIIKEKRDLMACAQTGSGKTAAFLLPILSQIYTDGPGEALKAMKENGR 258
           Y  PTP+Q    PI     + +  A+TGSGKT  ++LP +  I    P +          
Sbjct: 191 YKSPTPIQAQGWPIAMSGANFVGIAKTGSGKTLGYILPAIVHINNQQPLQ---------- 340

Query: 259 YGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADTVQQIRDLERGCHL 318
              R + PI+LVLAPTRELA QI + A +F   S VR   V+GGA    Q+RDL+RGC +
Sbjct: 341 ---RGEGPIALVLAPTRELAQQIQQVATEFGSSSYVRNTCVFGGAPKGGQMRDLQRGCEI 511

Query: 319 LVAT 322
           ++AT
Sbjct: 512 VIAT 523
>19640
          Length = 456

 Score = 89.0 bits (219), Expect(2) = 3e-18,   Method: Compositional matrix adjust.
 Identities = 38/88 (43%), Positives = 56/88 (63%)
 Frame = -1

Query: 445 VFVETKKGADSLENFLFQERYACTSIHGDRSQKDREEALHQFRSGRKPILVATAVAARGL 504
           +F  T++  D L   +    +  +++HGD  Q+DRE  + QFRSG   +L+ T + ARG+
Sbjct: 456 IFCNTRRKVDQLTQEMSSHNFTVSAMHGDMEQRDREVIMKQFRSGSSRVLITTDLLARGI 277

Query: 505 DISNVKHVINFDLPSDIEEYVHRIGRTG 532
           D+  V  VIN+DLPS+ E Y+HRIGR G
Sbjct: 276 DVQQVSLVINYDLPSNRENYIHRIGRGG 193

 Score = 21.2 bits (43), Expect(2) = 3e-18,   Method: Composition-based stats.
 Identities = 10/36 (27%), Positives = 18/36 (50%)
 Frame = -3

Query: 533 RVGNLGLATSFFNERNLNITKDLLDLLVEAKQEVPS 568
           R G  G+A +F  + +  I KD+        +E+P+
Sbjct: 193 RFGRKGVAINFITDDDRRILKDIEQFYHTTIEEMPA 86
>34295
          Length = 694

 Score = 84.0 bits (206), Expect = 2e-16,   Method: Compositional matrix adjust.
 Identities = 45/102 (44%), Positives = 58/102 (56%)
 Frame = -1

Query: 443 TLVFVETKKGADSLENFLFQERYACTSIHGDRSQKDREEALHQFRSGRKPILVATAVAAR 502
            ++F  TKK    L   L         +HG   QK+R  AL +F+S     L+AT VAAR
Sbjct: 535 VMIFTNTKKYCQLLSMTLTNMEIENVCLHGFMRQKERVSALSRFKSNHIRTLIATDVAAR 356

Query: 503 GLDISNVKHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFF 544
           GLDI +V+ VIN  LP   +EY+HR+GRT R G  G+A S F
Sbjct: 355 GLDIPSVQLVINHMLPRTPKEYIHRVGRTARAGRKGVAISIF 230
>12995
          Length = 1072

 Score = 80.5 bits (197), Expect = 2e-15,   Method: Compositional matrix adjust.
 Identities = 43/120 (35%), Positives = 67/120 (55%), Gaps = 1/120 (0%)
 Frame = +3

Query: 425 DKRSFLLDLL-NATGKDSLTLVFVETKKGADSLENFLFQERYACTSIHGDRSQKDREEAL 483
           DK + LL LL +   ++ LT+VFV TK   + L   L +   ACT I+    Q  R+  +
Sbjct: 81  DKEAMLLYLLRDVISENDLTVVFVATKHHVEYLNTLLTKCGIACTYIYSSLDQTARKIHV 260

Query: 484 HQFRSGRKPILVATAVAARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSF 543
            +F   +  +++ T +AARG+DI  + +V+NF  P+  + +VHR+GR  R G  G A S 
Sbjct: 261 AKFTHKQVKVMLVTDLAARGIDIPQLDNVVNFHFPAKAKLFVHRVGRVARAGRSGTAYSL 440
>19172
          Length = 484

 Score = 79.7 bits (195), Expect = 3e-15,   Method: Composition-based stats.
 Identities = 49/129 (37%), Positives = 77/129 (59%), Gaps = 3/129 (2%)
 Frame = -1

Query: 394 DFLDEYIFLAVGRVG-STSENITQKVVWVEELDKRSFLLDLLNATG--KDSLTLVFVETK 450
           +FL+ YI + +G +  S + NI Q V   +E +K + L+ LL       ++ T++FVETK
Sbjct: 484 EFLNNYIQVNIGSLSLSANHNILQIVDVCDESEKIAKLIQLLTQISGENETKTIIFVETK 305

Query: 451 KGADSLENFLFQERYACTSIHGDRSQKDREEALHQFRSGRKPILVATAVAARGLDISNVK 510
           K  D +   + ++ +   +IHGD+SQ++R+  L  FR+GR  ILVAT VAARGL     +
Sbjct: 304 KRVDEITRNISRQGWRACAIHGDKSQQERDFVLSSFRNGRHSILVATDVAARGLG----E 137

Query: 511 HVINFDLPS 519
             + F LP+
Sbjct: 136 FFVAFALPA 110
>00617
          Length = 1505

 Score = 74.7 bits (182), Expect = 1e-13,   Method: Compositional matrix adjust.
 Identities = 35/97 (36%), Positives = 59/97 (60%)
 Frame = -3

Query: 459  FLFQERYACTSIHGDRSQKDREEALHQFRSGRKPILVATAVAARGLDISNVKHVINFDLP 518
             L + +++C  +H    Q+ R  +L +F+S +  IL++T VA+RGLDI  V  +IN ++P
Sbjct: 1500 MLEKLQFSCAVLHSMIPQRFRLSSLSRFKSNQTRILISTDVASRGLDIPTVDLIINHNIP 1321

Query: 519  SDIEEYVHRIGRTGRVGNLGLATSFFNERNLNITKDL 555
            +   +YVHR+GRT R G  G + S   E ++ + K +
Sbjct: 1320 NRPRDYVHRVGRTARAGRCGQSISLVTEFDIKLIKSI 1210
>11160
          Length = 646

 Score = 65.5 bits (158), Expect(2) = 2e-12,   Method: Compositional matrix adjust.
 Identities = 63/193 (32%), Positives = 88/193 (45%), Gaps = 16/193 (8%)
 Frame = -1

Query: 301 GGADTVQQI-RDLERGCHLLVATPGRLVDMMERGKIGLDFC------KYLVLDEADRMLD 353
           GG      I + ++ G  +L+ATPGRL D+  R + G +        + LVLDEADR+LD
Sbjct: 646 GGVSCSHDISKFMKSGGSILIATPGRLDDLFSRKESGFNLAASVKALEVLVLDEADRLLD 467

Query: 354 MGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSE- 412
           MGFE  I  I+      PK +R T +FSAT   E++ L R  L   + + V       E 
Sbjct: 466 MGFEASINTILGH---LPK-LRRTGLFSATQTDEVENLIRAGLRNPLRVTVKEKKLAGEA 299

Query: 413 ------NITQKVVWVEELDKRSFLLDLLNATGKDSLTLVFVETKKGADSLENFLFQ--ER 464
                  ++   + VE  +K S L+  L    +D L L+F  T    D     L Q  + 
Sbjct: 298 DQRTPSTLSNYYMIVEAEEKFSQLVKFLKTHHRDKL-LLFFSTCACVDYFSMCLTQLLKH 122

Query: 465 YACTSIHGDRSQK 477
               SIH    QK
Sbjct: 121 MQVLSIHSKMKQK 83

 Score = 25.4 bits (54), Expect(2) = 2e-12,   Method: Composition-based stats.
 Identities = 15/35 (42%), Positives = 19/35 (54%), Gaps = 2/35 (5%)
 Frame = -3

Query: 473 DRSQKDREE--ALHQFRSGRKPILVATAVAARGLD 505
           D  Q + EE     +FRS    +LV T V ARG+D
Sbjct: 107 DSQQDEAEEKPVFAKFRSITSGLLVCTDVMARGVD 3
>17708
          Length = 882

 Score = 70.9 bits (172), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 39/115 (33%), Positives = 65/115 (56%)
 Frame = +1

Query: 217 RDLMACAQTGSGKTAAFLLPILSQIYTDGPGEALKAMKENGRYGRRKQYPISLVLAPTRE 276
           RDLM  A+TGSGKT AFL+P +  +Y       LK M  NG           ++++PTRE
Sbjct: 553 RDLMGAAKTGSGKTLAFLIPAIELMY------KLKFMPRNGTG--------CIIISPTRE 690

Query: 277 LAVQIYEEARKFSYRSRVRPCVVYGGADTVQQIRDLERGCHLLVATPGRLVDMME 331
           L++Q +    +          ++ GG +   +++ L++G +++VATPGRL+D ++
Sbjct: 691 LSMQTFNVLTELLKYHHHTFGLIMGGVNRHDEVKKLKKGVNIIVATPGRLLDHLQ 855
>39583
          Length = 234

 Score = 70.1 bits (170), Expect = 3e-12,   Method: Composition-based stats.
 Identities = 32/57 (56%), Positives = 42/57 (73%)
 Frame = -3

Query: 479 REEALHQFRSGRKPILVATAVAARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVG 535
           R EAL +F+ G   +L+AT +A+RGLDI  VK VINF +PS ++ YVHR+GRT R G
Sbjct: 172 RLEALKRFKEGEIDVLLATDLASRGLDIEGVKTVINFTMPSTLKHYVHRVGRTARAG 2
>11624
          Length = 2257

 Score = 69.7 bits (169), Expect = 3e-12,   Method: Compositional matrix adjust.
 Identities = 46/151 (30%), Positives = 78/151 (51%), Gaps = 3/151 (1%)
 Frame = -1

Query: 409 STSENITQKVVWVEELDKRSFLLDLLNATGKDSLTLVFVETKKGADSLENFLFQERYACT 468
           +T E +T+ +V  +  +K   +L  L+     S+ L F  + +    L   L  + Y   
Sbjct: 994 TTPEGLTEYIVESDSSEKPLLVLHFLHNLKFRSV-LCFTNSVETTHRL--CLLVKLYGGL 824

Query: 469 SIHGDRSQ---KDREEALHQFRSGRKPILVATAVAARGLDISNVKHVINFDLPSDIEEYV 525
           S+    S+   + R++ L QF  G+  +LV +   ARG+D+ NVK+VI++D P  I+ Y+
Sbjct: 823 SVKEFSSRLPGERRKKILKQFSKGKIDLLVCSDAMARGMDVDNVKYVISYDNPPYIKTYI 644

Query: 526 HRIGRTGRVGNLGLATSFFNERNLNITKDLL 556
           HR+GRT R G  G A S   ++     K ++
Sbjct: 643 HRVGRTARAGRAGTAISLLEKKEFFHFKQMM 551

 Score = 58.2 bits (139), Expect = 9e-09,   Method: Compositional matrix adjust.
 Identities = 46/147 (31%), Positives = 72/147 (48%), Gaps = 10/147 (6%)
 Frame = -3

Query: 217  RDLMACAQTGSGKTAAFLLPILSQIYTDGPGEALKAMKENGRYGRRKQYPISLVLAPTRE 276
            RD+   A TGSGKT A+ LPI+         + LK         R   +  ++++ P R+
Sbjct: 1814 RDICVSAPTGSGKTLAYTLPII---------QCLKQ--------RMVPHVRAVIVLPVRD 1686

Query: 277  LAVQIYEEARKFSYRSRVRPCVVYGGA------DTVQQIR---DLERGCHLLVATPGRLV 327
            LA Q+Y+    +   + ++  +V G        DT+ + R          +LVATPGRLV
Sbjct: 1685 LAEQVYQVFCHYCADTPLKVGIVVGKTVFNVEQDTLVKKRYGGVYHSVIDILVATPGRLV 1506

Query: 328  DMMERGK-IGLDFCKYLVLDEADRMLD 353
            D +       L   ++LV+DEADRM++
Sbjct: 1505 DHINSTPGFDLSHLRFLVIDEADRMME 1425
>19151
          Length = 625

 Score = 62.8 bits (151), Expect = 5e-10,   Method: Composition-based stats.
 Identities = 30/68 (44%), Positives = 45/68 (66%), Gaps = 7/68 (10%)
 Frame = -3

Query: 493 ILVATAVAARGLDISNVKHVINFDLP------SDIEEYVHRIGRTGRVGNLGLATSFFN- 545
           +L+ T V +RG+DI  V  V+NFDLP      +D E Y+HRIGRTGR G  G+A +  + 
Sbjct: 620 VLITTNVLSRGIDIEQVTIVVNFDLPIDLRGNADCETYLHRIGRTGRFGKSGIAINLIDG 441

Query: 546 ERNLNITK 553
           E+++N+ +
Sbjct: 440 EKSMNVCR 417
>12121
          Length = 465

 Score = 62.0 bits (149), Expect = 8e-10,   Method: Composition-based stats.
 Identities = 27/44 (61%), Positives = 32/44 (72%)
 Frame = -3

Query: 318 LLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIR 361
           + +ATPGRL+D +E  +  L  C YLVLDEADRMLDMGF P  R
Sbjct: 463 ICIATPGRLIDFLESNRTNLRRCTYLVLDEADRMLDMGFXPP*R 332

 Score = 36.6 bits (83), Expect = 0.030,   Method: Composition-based stats.
 Identities = 19/62 (30%), Positives = 27/62 (43%)
 Frame = -2

Query: 167 VEATGNNCPPHIENFSDXXXXXXXXXXXXLTRYTRPTPVQKHAIPIIKEKRDLMACAQTG 226
           +  +G   P  I  F +               +T PTP+Q  + PI    +DL+  AQTG
Sbjct: 188 ITLSGRYLPNPILTFEEANLPDYVMSQIHRNNWTSPTPIQSQSWPIAMSGKDLVGIAQTG 9

Query: 227 SG 228
           SG
Sbjct: 8   SG 3
>31220
          Length = 818

 Score = 55.8 bits (133), Expect = 5e-08,   Method: Compositional matrix adjust.
 Identities = 26/60 (43%), Positives = 36/60 (60%)
 Frame = +2

Query: 500 AARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNERNLNITKDLLDLL 559
           A+RG+D   V +VINFD P D+  Y+HR GRT R  N G   SF + + L I + + + L
Sbjct: 161 ASRGIDFQGVNNVINFDFPLDVTSYIHRAGRTARGNNTGSVLSFVSVKELPINQAVEEKL 340
>10649
          Length = 472

 Score = 53.5 bits (127), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 26/64 (40%), Positives = 34/64 (53%)
 Frame = +1

Query: 470 IHGDRSQKDREEALHQFRSGRKPILVATAVAARGLDISNVKHVINFDLPSDIEEYVHRIG 529
           +HG   Q  R +   +F   +  IL+ T +A RGLD   V  VI  D P D+  Y+HR G
Sbjct: 82  LHGGIPQLRRLDIYREFCRKQHVILITTDLACRGLDFPAVNWVIQLDCPVDVNTYIHRAG 261

Query: 530 RTGR 533
           RT R
Sbjct: 262 RTAR 273
>03381
          Length = 1206

 Score = 53.5 bits (127), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 25/73 (34%), Positives = 41/73 (56%)
 Frame = +3

Query: 504 LDISNVKHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNERNLNITKDLLDLLVEAK 563
           LDI +++ V+N+D+  DI+ + HR+GRTGR G  G A +   +++      L+  L  A 
Sbjct: 3   LDIPHIRTVVNYDVARDIDTHTHRVGRTGRAGEKGSAYTLITDKDKEFAPLLVRNLEGAN 182

Query: 564 QEVPSWLESMAYE 576
           Q  P  L  +A +
Sbjct: 183 QTPPPALLDLANQ 221
>08036
          Length = 1226

 Score = 52.8 bits (125), Expect = 5e-07,   Method: Compositional matrix adjust.
 Identities = 21/45 (46%), Positives = 29/45 (64%)
 Frame = +3

Query: 501 ARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFN 545
           ARG+D  NV +VINF+ P  ++ Y+HR+GRT R    G A S  +
Sbjct: 612 ARGIDFQNVSNVINFEFPKTVDAYIHRVGRTARGDKQGCALSLIS 746
>31899
          Length = 453

 Score = 51.6 bits (122), Expect = 1e-06,   Method: Composition-based stats.
 Identities = 32/85 (37%), Positives = 45/85 (52%)
 Frame = -1

Query: 199 YTRPTPVQKHAIPIIKEKRDLMACAQTGSGKTAAFLLPILSQIYTDGPGEALKAMKENGR 258
           + RP+P+Q  AIP+ +   DL+  A++G+GKT  F +  L  I T               
Sbjct: 285 FERPSPIQLKAIPLGRCGLDLIVQAKSGTGKTCVFSVVALEGIETT-------------- 148

Query: 259 YGRRKQYPISLVLAPTRELAVQIYE 283
             R  Q    LVLAPTRE+A+QI+E
Sbjct: 147 -ARSTQV---LVLAPTREIALQIWE 85
>11423
          Length = 1434

 Score = 44.3 bits (103), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 18/47 (38%), Positives = 28/47 (59%)
 Frame = -2

Query: 510  KHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNERNLNITKDLL 556
            K+VI++D P  I+ Y+HR+GRT R G  G A S   ++     K ++
Sbjct: 1397 KYVISYDNPPYIKTYIHRVGRTARAGRAGTAISLLEKKEFFHFKQMM 1257
>33083
          Length = 1931

 Score = 43.9 bits (102), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 24/69 (34%), Positives = 36/69 (52%), Gaps = 1/69 (1%)
 Frame = +1

Query: 502 RGLDISNVKHVINFDLPSDIEEYVHRIGRTGR-VGNLGLATSFFNERNLNITKDLLDLLV 560
           RGLDI  V  ++ +D P + +EY+HR+GRT R  G+ G A        L   K L    V
Sbjct: 1   RGLDIPQVDWIVQYDPPDESKEYIHRVGRTARGEGSSGKALLLLQPEELGFLKFLRAAKV 180

Query: 561 EAKQEVPSW 569
           + ++   +W
Sbjct: 181 KVQEMDFNW 207
>06438
          Length = 989

 Score = 43.9 bits (102), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 18/39 (46%), Positives = 22/39 (56%)
 Frame = +1

Query: 495 VATAVAARGLDISNVKHVINFDLPSDIEEYVHRIGRTGR 533
           +   +A RGLD   V  VI  D P D+  Y+HR GRT R
Sbjct: 25  LTVTLACRGLDFPAVNWVIQLDCPVDVNTYIHRAGRTAR 141
>34134
          Length = 271

 Score = 41.2 bits (95), Expect = 0.001,   Method: Composition-based stats.
 Identities = 25/65 (38%), Positives = 31/65 (47%)
 Frame = +3

Query: 210 IPIIKEKRDLMACAQTGSGKTAAFLLPILSQIYTDGPGEALKAMKENGRYGRRKQYPISL 269
           +PI    RD +  AQTGSGKT +F+LP +  I      E             R   PI+L
Sbjct: 84  VPIAMSGRDCVGIAQTGSGKTLSFILPAIVHINHQPTLE-------------RGDGPIAL 224

Query: 270 VLAPT 274
           VL PT
Sbjct: 225 VLVPT 239
>01821
          Length = 910

 Score = 35.8 bits (81), Expect = 0.061,   Method: Compositional matrix adjust.
 Identities = 17/40 (42%), Positives = 23/40 (57%)
 Frame = +1

Query: 494 LVATAVAARGLDISNVKHVINFDLPSDIEEYVHRIGRTGR 533
           LV+T V   GLDI +V  ++ +D        V R+GRTGR
Sbjct: 13  LVSTCVGEEGLDIGDVDLIVCYDAHKSPVRLVQRMGRTGR 132
>01797
          Length = 1448

 Score = 35.4 bits (80), Expect = 0.070,   Method: Compositional matrix adjust.
 Identities = 21/100 (21%), Positives = 49/100 (49%), Gaps = 3/100 (3%)
 Frame = -3

Query: 439 KDSLTLVFVETKKGADSLENFLFQERYACTSIHGDRSQKDREEALHQFR---SGRKPILV 495
           +DS  L+F +  +  D LE++ F   +    + G    +DR++++ +F    S +   ++
Sbjct: 573 QDSRVLIFSQMTRMLDILEDYCFWRGFDYCRLDGSTPHEDRQKSILEFNAPDSSKFVFML 394

Query: 496 ATAVAARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVG 535
           +T     G++++    VI +D   + +  +  + R  R+G
Sbjct: 393 STRAGGLGINLATADIVILYDSDWNPQVDLQAMDRAHRIG 274
>33543
          Length = 471

 Score = 32.7 bits (73), Expect = 0.47,   Method: Compositional matrix adjust.
 Identities = 16/53 (30%), Positives = 27/53 (50%), Gaps = 1/53 (1%)
 Frame = +3

Query: 524 YVHRIGRTGRVGNLGLATSFF-NERNLNITKDLLDLLVEAKQEVPSWLESMAY 575
           Y+HR+GR GR G  GLA +F  NE   ++   + +    +  ++P  +    Y
Sbjct: 6   YLHRVGRAGRFGTRGLAITFVSNETEADVLNSVQERFEVSVTDLPEQISVSTY 164
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|30424591|ref|NP_776112.1| ilvB (bacterial
acetolactate synthase)-like [Mus musculus]
         (632 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

02928                                                                 428   e-120
04384                                                                 202   2e-55
11777                                                                  61   2e-09
12890                                                                  51   2e-06
22483                                                                  44   3e-04
18033                                                                  29   5.2  
>02928
          Length = 1057

 Score =  428 bits (1101), Expect = e-120,   Method: Compositional matrix adjust.
 Identities = 208/352 (59%), Positives = 257/352 (73%), Gaps = 1/352 (0%)
 Frame = +1

Query: 76  GHISPLLVACEKLGIRVVDTRHEVTAVFAADXXXXXXXXXXXXXXXXXXXXXNTVTAVKN 135
           GHISP+LVACEK+GIRVVDTRHEVTAVFAAD                     NTVTAVKN
Sbjct: 1   GHISPILVACEKIGIRVVDTRHEVTAVFAADAVARMSGTVGVAAVTAGPGLTNTVTAVKN 180

Query: 136 AQVAQSPVLLLGGAASTLLQKRGALQAIDQMSLFRPLCKFCASVRRVRDIVPTLRTAIAA 195
           AQ+A+SPVLL+GGAA+TLL+ RGALQ IDQMSLF+PLCK+CA+V  VR+IVPTLR A+  
Sbjct: 181 AQMAESPVLLIGGAAATLLKGRGALQDIDQMSLFKPLCKYCATVSTVREIVPTLRKALQV 360

Query: 196 AQSGTPGPVFVELPLDVLYPYFMVEKEM-IPTKLPNSLMGRVVVWYLQNCLANLFVGAWE 254
           AQSGTPGPVFVE P+D LY Y +V++E+ +  K P SLM +VV WYLQN L+NLF GAWE
Sbjct: 361 AQSGTPGPVFVEFPIDTLYMYDLVKREIGMKDKGPTSLMQKVVNWYLQNHLSNLFAGAWE 540

Query: 255 PRPEGPLPLDIPQASPQQVQRCVEILSRAKRPLLVLGSQALLPPTPANKLRAAVETLGVP 314
           PR   PLP+ IP+AS  Q+Q+C++++S+AK+P+++LGSQ+ LPPTP  +LR A+E LG+P
Sbjct: 541 PRDTSPLPVSIPRASDSQIQQCIKLVSKAKKPVILLGSQSTLPPTPVEELRTALEDLGIP 720

Query: 315 CFLGGMSRGLLGRNHPLHIRQNRSXXXXXXXXXXXXXXXCDFRLSYGRVLNRKSSIIIVN 374
           CFLGGMSRGLLGR+  + +RQ R                CDFRL YGRVL+R+S II +N
Sbjct: 721 CFLGGMSRGLLGRHSDIQVRQQRRDALKEADLVILAGAVCDFRLGYGRVLSRRSKIIAIN 900

Query: 375 RNRDDLLLNSDIFWKPQEAVQGDVGSFMIKLVEGLQGQMWSSDWAEELRKAD 426
           R++D L  N+D+FWKP  AVQGDVGS M  +  GL+G     DW   LR  D
Sbjct: 901 RDKDQLWKNADMFWKPTVAVQGDVGSTMAAVCRGLKGYKCDPDWLALLRSRD 1056
>04384
          Length = 779

 Score =  202 bits (514), Expect(2) = 2e-55,   Method: Compositional matrix adjust.
 Identities = 91/144 (63%), Positives = 116/144 (80%)
 Frame = +2

Query: 470 DFVATAAYLVQPRGPLRWLDPGAFGTLGVGAGFALGAKLCQPEAEVWCLFGDGAFGYSLI 529
           DFVATAAY+++PRGPL WLDPGAFGTLGVG GFALGAKLC+P+++VW ++GDG+ GYS+ 
Sbjct: 2   DFVATAAYILRPRGPLCWLDPGAFGTLGVGGGFALGAKLCRPDSDVWIIYGDGSLGYSVA 181

Query: 530 EFDTFVRHKVPVIALVGNDAGWTQISREQVPRLGSDVACSLAYTDYHKAAMGLGAQGLIL 589
           EFDTF RHK PV+ALVGNDAGWTQI+REQVP   S VAC LA++DY   A G G +G+ L
Sbjct: 182 EFDTFTRHKTPVLALVGNDAGWTQIAREQVPLFNSSVACDLAFSDYEDVARGYGGKGVRL 361

Query: 590 SRDNKDQVVKVLREGQQLCQDGHA 613
            R N+D++  VL++  +  + GH+
Sbjct: 362 DRSNEDKMAAVLQQALKDYRQGHS 433

 Score = 32.3 bits (72), Expect(2) = 2e-55,   Method: Compositional matrix adjust.
 Identities = 13/18 (72%), Positives = 18/18 (100%)
 Frame = +1

Query: 615 VVNILIGRTDFRDGSISV 632
           +VN+LIG+T+FR+GSISV
Sbjct: 439 LVNVLIGKTNFREGSISV 492
>11777
          Length = 436

 Score = 60.8 bits (146), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 44/126 (34%), Positives = 66/126 (52%), Gaps = 8/126 (6%)
 Frame = +2

Query: 415 SSDWAEELR---KADQQK-EQTYRDKALMPVLQHLNPVWVLQQVEETLPDNALLVVDGGD 470
           SS W   LR    A+Q+  E+  +D  +      LN      +V+++LP + L+V +G +
Sbjct: 74  SSPWWGTLRAKISANQKNVEEMSKDHGI-----PLNYYAAFAEVQKSLPKDCLIVNEGSN 238

Query: 471 FVATAAYLVQPRGPLRWLDPGAFGTLGVGAGFALGAKL-CQ---PEAEVWCLFGDGAFGY 526
            +     ++    P   LD G FGT+GVG GFAL A L C+   P   V C+ GD AFG+
Sbjct: 239 TMDIGRTMLPNNLPRHRLDAGTFGTMGVGIGFALAAALWCRDYAPGKRVVCVEGDSAFGF 418

Query: 527 SLIEFD 532
           S +E +
Sbjct: 419 SGMEIE 436
>12890
          Length = 418

 Score = 50.8 bits (120), Expect = 2e-06,   Method: Composition-based stats.
 Identities = 29/59 (49%), Positives = 36/59 (61%), Gaps = 4/59 (6%)
 Frame = -2

Query: 488 LDPGAFGTLGVGAGFALGAKL-CQ---PEAEVWCLFGDGAFGYSLIEFDTFVRHKVPVI 542
           LD G FGT+GVG GFAL A L C+   P   V C+ GD AFG+SL     F R+  P++
Sbjct: 282 LDAGTFGTMGVGIGFALAAALWCRDYAPGKRVVCVEGDSAFGFSL-----FYRNISPLV 121
>22483
          Length = 676

 Score = 43.5 bits (101), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 26/45 (57%), Positives = 30/45 (66%), Gaps = 4/45 (8%)
 Frame = +1

Query: 488 LDPGAFGTLGVGAGFALGAKL-CQ---PEAEVWCLFGDGAFGYSL 528
           LD G FGT+GVG GFAL A L C+   P   V C+ GD AFG+SL
Sbjct: 319 LDAGTFGTMGVGIGFALAAALWCRDYAPGKRVVCVEGDSAFGFSL 453
>18033
          Length = 587

 Score = 29.3 bits (64), Expect = 5.2,   Method: Composition-based stats.
 Identities = 10/28 (35%), Positives = 18/28 (64%)
 Frame = +3

Query: 236 VVVWYLQNCLANLFVGAWEPRPEGPLPL 263
           VV+W   +CL+N ++   E   +GP+P+
Sbjct: 24  VVLWQRAHCLSNSYLAVLEDSSDGPVPV 107
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|55926127|ref|NP_067262.1| spectrin beta 3 [Mus
musculus]
         (2388 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

19002                                                                 431   e-120
17613                                                                 106   6e-53
19147                                                                 129   1e-29
34010                                                                 124   2e-28
26578                                                                 123   1e-27
05733                                                                  80   7e-15
28965                                                                  77   8e-14
29446                                                                  74   5e-13
34417                                                                  67   1e-10
11159                                                                  66   2e-10
19246                                                                  66   2e-10
25051                                                                  65   4e-10
38533                                                                  56   2e-07
22703                                                                  55   2e-07
29517                                                                  53   2e-06
17567                                                                  48   4e-05
04951                                                                  48   6e-05
09711                                                                  47   9e-05
09100                                                                  37   0.14 
29667                                                                  35   0.50 
32371                                                                  34   0.72 
18202                                                                  33   1.7  
>19002
          Length = 842

 Score =  431 bits (1107), Expect = e-120,   Method: Compositional matrix adjust.
 Identities = 198/259 (76%), Positives = 227/259 (87%)
 Frame = -2

Query: 108 KGRMRIHCLENVDKALQFLKEQKVHLENMGSHDIVDGNHRLTLGLVWTIILRFQIQDISV 167
           KG+MRIHCLENVDKAL FL EQ+VHLENMG+HDIVDG+ RLTLGL+WTIILRFQIQDI +
Sbjct: 778 KGKMRIHCLENVDKALTFLHEQRVHLENMGAHDIVDGSSRLTLGLIWTIILRFQIQDIMI 599

Query: 168 ETEDNKEKKSAKDALLLWCQMKTAGYPNVNVHNFTTSWRDGLAFNAIVHKHRPDLLDFES 227
           E  DN E KSAKDALLLWCQMKTAGYPNVNV NFTTSWRDGLAFNAI+HKHRPDL+ ++ 
Sbjct: 598 EEVDNSETKSAKDALLLWCQMKTAGYPNVNVRNFTTSWRDGLAFNAIIHKHRPDLVQYDR 419

Query: 228 LKKCNAHYNLQNAFNLAEKELGLTKLLDPEDVNVDQPDEKSIITYVATYYHYFSKMKALA 287
           L K +A  NLQNAF +AE +LGLT LL+PEDVNV+ PDEKSIITYV TYYHYFSKMKA +
Sbjct: 418 LHKSSAIQNLQNAFTVAEDKLGLTALLEPEDVNVEYPDEKSIITYVVTYYHYFSKMKADS 239

Query: 288 VEGKRIGKVLDHAMEAEHLVEKYESLASELLQWIEQTIVTLNDRQLANSLSGVQNQLQSF 347
           V+GKRIGKV+D+A+  E+ +E+YE+L S+LL+WIEQTIV L DRQ ANSL+GVQ QL +F
Sbjct: 238 VQGKRIGKVIDNAINTENSIEEYETLTSDLLEWIEQTIVILRDRQFANSLTGVQQQLAAF 59

Query: 348 NSYRTVEKPPKFTEKGNLE 366
           N+YR VEKPPKF EKGNLE
Sbjct: 58  NTYRIVEKPPKFDEKGNLE 2
>17613
          Length = 1108

 Score =  106 bits (265), Expect(3) = 6e-53,   Method: Compositional matrix adjust.
 Identities = 54/132 (40%), Positives = 79/132 (59%), Gaps = 1/132 (0%)
 Frame = +3

Query: 238 QNAFNLAEKELGLTKLLDPED-VNVDQPDEKSIITYVATYYHYFSKMKALAVEGKRIGKV 296
           Q+ F    K L + ++LDPED VN  +PDE+S++ YV++YYH FS  +       RI KV
Sbjct: 366 QHCF*HRRKHLDIPRMLDPEDMVNSAKPDERSVMAYVSSYYHAFSGAQQAETAANRICKV 545

Query: 297 LDHAMEAEHLVEKYESLASELLQWIEQTIVTLNDRQLANSLSGVQNQLQSFNSYRTVEKP 356
           L    E E L+E+YE LAS+LL+WI +T   L +R   N+L G +++L  F  YR  +KP
Sbjct: 546 LKVNQENERLMEEYERLASDLLEWIRRTRPWLENRVTDNTLPGTRHKLDEFRDYRRKQKP 725

Query: 357 PKFTEKGNLEVL 368
           P +  + +   L
Sbjct: 726 PSWRTRPSWRTL 761

 Score = 73.6 bits (179), Expect(3) = 6e-53,   Method: Composition-based stats.
 Identities = 33/57 (57%), Positives = 43/57 (75%)
 Frame = +1

Query: 189 KTAGYPNVNVHNFTTSWRDGLAFNAIVHKHRPDLLDFESLKKCNAHYNLQNAFNLAE 245
           KTA Y NVNV NF  S++DGLAF A++H+HRP+L+D+ SL K N   NL  AF++AE
Sbjct: 220 KTAPYKNVNVQNFHLSFKDGLAFCALIHRHRPELIDYHSLSKDNPLENLNTAFDIAE 390

 Score = 69.3 bits (168), Expect(3) = 6e-53,   Method: Composition-based stats.
 Identities = 33/59 (55%), Positives = 45/59 (76%)
 Frame = +2

Query: 131 VHLENMGSHDIVDGNHRLTLGLVWTIILRFQIQDISVETEDNKEKKSAKDALLLWCQMK 189
           V L ++G+ +IVDGN ++TLG++WTIILRF IQDI+V      E+ +AK+ LLLWCQ K
Sbjct: 65  VKLVSIGAEEIVDGNVKMTLGMIWTIILRFAIQDITV------EELTAKEGLLLWCQRK 223

 Score = 85.9 bits (211), Expect = 2e-16,   Method: Compositional matrix adjust.
 Identities = 48/127 (37%), Positives = 74/127 (58%), Gaps = 1/127 (0%)
 Frame = +2

Query: 357 PKFTEKGNLEVLLFTIQSKLRANNQKVYTPREGRLISDINKAWERLEKAEHERELALRTE 416
           PK  +K  LE    T+Q++LR +N+  Y P EG+++SDI  AW+ LE AE   E  L +E
Sbjct: 725 PKLEDKAKLENSFNTLQTRLRLSNRPAYLPTEGKMVSDIANAWKGLEHAEKGFEEWLLSE 904

Query: 417 LIRQEKLEQLAARFDRKAAMRETWLSENQRLVSQDNFG-LELAAVEAAVRKHEAIETDIV 475
           L R E+L+ LA +F  K  + E W    + ++   +F    L  ++A  +KHEA E+D+ 
Sbjct: 905 LQRLERLDHLAQKFRHKCEIHEEWSQGKEDMLQSRDFKQCRLNELKAMKKKHEAFESDLA 1084

Query: 476 AYSGRVQ 482
           A+  RV+
Sbjct: 1085AHQDRVE 1105
>19147
          Length = 474

 Score =  129 bits (323), Expect(2) = 1e-29,   Method: Composition-based stats.
 Identities = 58/106 (54%), Positives = 81/106 (76%)
 Frame = +1

Query: 125 FLKEQKVHLENMGSHDIVDGNHRLTLGLVWTIILRFQIQDISVETEDNKEKKSAKDALLL 184
           ++  + V L ++G+ +IVDGN ++TLG++WTIILRF IQDI+VE      + +AK+ LLL
Sbjct: 49  YIASKGVKLVSIGAEEIVDGNVKMTLGMIWTIILRFAIQDITVE------ELTAKEGLLL 210

Query: 185 WCQMKTAGYPNVNVHNFTTSWRDGLAFNAIVHKHRPDLLDFESLKK 230
           WCQ KTA Y NVNV NF  S++DGLAF A++H+HRP+L+D+ SL K
Sbjct: 211 WCQRKTAPYKNVNVQNFHLSFKDGLAFCALIHRHRPELIDYHSLSK 348

 Score = 21.9 bits (45), Expect(2) = 1e-29,   Method: Composition-based stats.
 Identities = 9/21 (42%), Positives = 15/21 (71%)
 Frame = +3

Query: 110 RMRIHCLENVDKALQFLKEQK 130
           +MR H + NV+KAL+  + Q+
Sbjct: 3   KMRFHKIANVNKALELHRLQR 65
>34010
          Length = 832

 Score =  124 bits (312), Expect(2) = 2e-28,   Method: Compositional matrix adjust.
 Identities = 63/132 (47%), Positives = 90/132 (68%), Gaps = 1/132 (0%)
 Frame = +3

Query: 1923 MDGINLQMDAQE-RPRDVSSADLVIKNQQGIKAEIEARADRFSSCIDMGQELLARSHYAA 1981
            +DG + Q D    +PRDVS  +L++ N Q +KAEI+AR + F+ CI++G++LL R HY  
Sbjct: 45   VDGRHHQTDEHAGKPRDVSGVELLMNNHQSLKAEIDAREENFAICINLGRDLLNRKHYRQ 224

Query: 1982 EEISEKLSQLQSRRQETADKWQEKMDWLQLVLEVLVFGRDAGMAEAWLCSQEPLVRSAEL 2041
            EE+ EKL QL   R +  D W+++ + LQL+LEV  F RDA +AEAWL +QE    + +L
Sbjct: 225  EEVREKLIQLTLERLDMTDLWKDRWEHLQLILEVYQFARDAAVAEAWLVAQEQYFLNQDL 404

Query: 2042 GCTVDEVESLIK 2053
            G T+D VE+LIK
Sbjct: 405  GDTLDAVENLIK 440

 Score = 21.9 bits (45), Expect(2) = 2e-28,   Method: Compositional matrix adjust.
 Identities = 9/13 (69%), Positives = 10/13 (76%)
 Frame = +1

Query: 2066 EERFSALEKLTAL 2078
            EERF+ALEK T  
Sbjct: 475  EERFAALEKPTTF 513

 Score = 39.3 bits (90), Expect = 0.019,   Method: Compositional matrix adjust.
 Identities = 33/111 (29%), Positives = 50/111 (45%), Gaps = 13/111 (11%)
 Frame = +3

Query: 1518 KDLPSVQLLMKKNQTLQKEIQGHEPRIA-------DLKERQRTL------GTAAAGPELA 1564
            +D+  V+LLM  +Q+L+ EI   E   A       DL  R+                E  
Sbjct: 90   RDVSGVELLMNNHQSLKAEIDAREENFAICINLGRDLLNRKHYRQEEVREKLIQLTLERL 269

Query: 1565 ELQEMWKRLSHELELRGKRLEEALRAQQFYRDAAEAEAWMGEQELHMMGQE 1615
            ++ ++WK        R + L+  L   QF RDAA AEAW+  QE + + Q+
Sbjct: 270  DMTDLWKD-------RWEHLQLILEVYQFARDAAVAEAWLVAQEQYFLNQD 401

 Score = 32.7 bits (73), Expect = 1.9,   Method: Composition-based stats.
 Identities = 14/30 (46%), Positives = 18/30 (60%)
 Frame = +1

Query: 1907 TDKFRFFKAVRELMLWMDGINLQMDAQERP 1936
            +D +RF     +L LWMD I  QM+ QE P
Sbjct: 1    SDFYRFMLMAHDLHLWMDDIIRQMNTQENP 90
>26578
          Length = 430

 Score =  123 bits (308), Expect = 1e-27,   Method: Compositional matrix adjust.
 Identities = 56/113 (49%), Positives = 82/113 (72%)
 Frame = +1

Query: 1705 DLEQWIQEREVVAASHELGQDYEHVTMLRDKFREFSKDTSTIGQERVDSXXXXXXXXXXX 1764
            DL QWI E+ +VA S++ GQDYEHV+ML+++F+EF++DT ++GQERV S           
Sbjct: 61   DLLQWIAEKSLVAGSNDPGQDYEHVSMLKEQFKEFARDTESMGQERVASANEICDQLIAL 240

Query: 1765 XXXXRATVAEWKDSLNEAWADLLELLDTRGQVLAAAYELQRFLHGARQALARV 1817
                 A++AEWKD++NEAWADLLEL+DTR Q+L +++EL +FL+  +  L R+
Sbjct: 241  DHSDSASIAEWKDNVNEAWADLLELIDTRTQLLQSSWELHKFLYECKDTLERI 399

 Score = 30.4 bits (67), Expect = 8.4,   Method: Compositional matrix adjust.
 Identities = 32/112 (28%), Positives = 47/112 (41%), Gaps = 1/112 (0%)
 Frame = +1

Query: 543 LMDWMAEMKGRLQSQDLGKHLAGVEDLL-QLHELVEADIAVQAERVRAVSASALRFCDPG 601
           L+ W+AE      S D G+    V  L  Q  E      ++  ERV    ASA   CD  
Sbjct: 64  LLQWIAEKSLVAGSNDPGQDYEHVSMLKEQFKEFARDTESMGQERV----ASANEICDQL 231

Query: 602 KEYRPCDPQLVSERVATLEQSYEALCELAATRRARLEESRRLWRFLWEVGEA 653
                 D   ++E    + +++  L EL  TR   L+ S  L +FL+E  + 
Sbjct: 232 IALDHSDSASIAEWKDNVNEAWADLLELIDTRTQLLQSSWELHKFLYECKDT 387
>05733
          Length = 1021

 Score = 80.5 bits (197), Expect = 7e-15,   Method: Compositional matrix adjust.
 Identities = 39/103 (37%), Positives = 64/103 (62%), Gaps = 3/103 (2%)
 Frame = +2

Query: 181 ALLLWCQ--MKTAGYPNVNVHNFTTSWRDGLAFNAIVHKHRPDLLDFESLKKCNAHYNLQ 238
           +LL WCQ  +    Y  V++ +FT+SWR GLAF A++H  RP L+   SL +C    N Q
Sbjct: 467 SLLRWCQRVLNXGTYRGVHIIDFTSSWRSGLAFCALIHAFRPHLISPASLMECETVKNNQ 646

Query: 239 NAFNLAEKELGLTKLLDPEDV-NVDQPDEKSIITYVATYYHYF 280
            AF++A+KELG+  ++  ED+     PD+ +++ Y++ ++  F
Sbjct: 647 LAFDVAQKELGIAPVMRGEDMAACAVPDKLTMVAYLSQFHELF 775
>28965
          Length = 421

 Score = 77.0 bits (188), Expect = 8e-14,   Method: Compositional matrix adjust.
 Identities = 46/115 (40%), Positives = 67/115 (58%)
 Frame = +2

Query: 907  RVTAVNDIAEQLLKASPPGKDRIIGTQEQLNQRWQQFRSLADGKKAALTSALSIQNYHLE 966
            +V  VN +AEQL+    P ++ I   QE++N+ W++ R L+  ++  L  A  IQ ++ +
Sbjct: 29   KVVEVNTLAEQLVTDGHPEEETIRQKQEEVNEAWKRLRQLSLLRQERLYGAHEIQRFNRD 208

Query: 967  CTETQAWMREKTKVIESTQGLGNDLAGVLALQRKLAGTERDLEAISARVGELTQE 1021
              ET AW++EK  V+ ST   G DLA V  LQRK  G ERDL A+  +V  L  E
Sbjct: 209  ADETIAWIQEKDAVL-STDDYGRDLASVQTLQRKHEGVERDLAALEEKVNALGTE 370

 Score = 60.1 bits (144), Expect = 9e-09,   Method: Compositional matrix adjust.
 Identities = 40/109 (36%), Positives = 63/109 (57%), Gaps = 1/109 (0%)
 Frame = +2

Query: 1771 TVAEWKDSLNEAWADLLELLDTRGQVLAAAYELQRFLHGARQALARVQHKQQQLP-DGTG 1829
            T+ + ++ +NEAW  L +L   R + L  A+E+QRF   A + +A +Q K   L  D  G
Sbjct: 92   TIRQKQEEVNEAWKRLRQLSLLRQERLYGAHEIQRFNRDADETIAWIQEKDAVLSTDDYG 271

Query: 1830 RDLNAAEALQRRHCAYEHDIQALSTQVQQVQDDGQRLQKAYAGDKAEEI 1878
            RDL + + LQR+H   E D+ AL  +V  +  +  RLQ  + GD++E+I
Sbjct: 272  RDLASVQTLQRKHEGVERDLAALEEKVNALGTESVRLQGIH-GDQSEQI 415

 Score = 51.6 bits (122), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 32/90 (35%), Positives = 52/90 (57%), Gaps = 2/90 (2%)
 Frame = +2

Query: 394 DINKAWERLEKAEHERELALRTELIRQEKL--EQLAARFDRKAAMRETWLSENQRLVSQD 451
           ++N+AW+RL      R+L+L    +RQE+L       RF+R A     W+ E   ++S D
Sbjct: 113 EVNEAWKRL------RQLSL----LRQERLYGAHEIQRFNRDADETIAWIQEKDAVLSTD 262

Query: 452 NFGLELAAVEAAVRKHEAIETDIVAYSGRV 481
           ++G +LA+V+   RKHE +E D+ A   +V
Sbjct: 263 DYGRDLASVQTLQRKHEGVERDLAALEEKV 352

 Score = 49.3 bits (116), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 32/94 (34%), Positives = 54/94 (57%)
 Frame = +2

Query: 1466 VEEKFRALCQPMKERCRRLHASREQHQFHRDVEDEILWVTERLPMASSLEHGKDLPSVQL 1525
            V E ++ L Q    R  RL+ + E  +F+RD ++ I W+ E+  + S+ ++G+DL SV  
Sbjct: 116  VNEAWKRLRQLSLLRQERLYGAHEIQRFNRDADETIAWIQEKDAVLSTDDYGRDLASV-- 289

Query: 1526 LMKKNQTLQKEIQGHEPRIADLKERQRTLGTAAA 1559
                 QTLQ++ +G E  +A L+E+   LGT + 
Sbjct: 290  -----QTLQRKHEGVERDLAALEEKVNALGTESV 376

 Score = 48.5 bits (114), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 38/124 (30%), Positives = 59/124 (47%), Gaps = 6/124 (4%)
 Frame = +2

Query: 1534 QKEIQGHEPRIADLKERQRTLGTAAAGPELA------ELQEMWKRLSHELELRGKRLEEA 1587
            QK++Q HE ++ ++      L T     E        E+ E WKRL     LR +RL  A
Sbjct: 2    QKDLQNHEDKVVEVNTLAEQLVTDGHPEEETIRQKQEEVNEAWKRLRQLSLLRQERLYGA 181

Query: 1588 LRAQQFYRDAAEAEAWMGEQELHMMGQEKAKDELSAQAEVKKHQVLEQALADYAQTIKQL 1647
               Q+F RDA E  AW+ E++  +   +  +D  S Q   +KH+ +E+ LA   + +  L
Sbjct: 182  HEIQRFNRDADETIAWIQEKDAVLSTDDYGRDLASVQTLQRKHEGVERDLAALEEKVNAL 361

Query: 1648 AASS 1651
               S
Sbjct: 362  GTES 373

 Score = 46.2 bits (108), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 23/81 (28%), Positives = 44/81 (54%)
 Frame = +2

Query: 1353 VVSEKLEDLHRRWDELETTTQAKARSLFDANRAELFAQSCSALESWLESLQAQLHSDDYG 1412
             + +K E+++  W  L   +  +   L+ A+  + F +      +W++   A L +DDYG
Sbjct: 92   TIRQKQEEVNEAWKRLRQLSLLRQERLYGAHEIQRFNRDADETIAWIQEKDAVLSTDDYG 271

Query: 1413 KDLTSVNILLKKQQMLEREMA 1433
            +DL SV  L +K + +ER++A
Sbjct: 272  RDLASVQTLQRKHEGVERDLA 334

 Score = 39.3 bits (90), Expect = 0.018,   Method: Compositional matrix adjust.
 Identities = 21/74 (28%), Positives = 42/74 (56%)
 Frame = +2

Query: 619 LEQSYEALCELAATRRARLEESRRLWRFLWEVGEAEAWVREQQHLLASADTGRDLTGVLR 678
           + ++++ L +L+  R+ RL  +  + RF  +  E  AW++E+  +L++ D GRDL  V  
Sbjct: 116 VNEAWKRLRQLSLLRQERLYGAHEIQRFNRDADETIAWIQEKDAVLSTDDYGRDLASVQT 295

Query: 679 LLNKHAALRGEMSG 692
           L  KH  +  +++ 
Sbjct: 296 LQRKHEGVERDLAA 337

 Score = 37.7 bits (86), Expect = 0.060,   Method: Compositional matrix adjust.
 Identities = 34/125 (27%), Positives = 57/125 (45%)
 Frame = +2

Query: 1124 LRTLGEEVTRDQADPQCLFLRQRLEALGTGWEELGRMWESRQGRLAQAHGFQGFLRDARQ 1183
            + TL E++  D   P+   +RQ+ E +   W+ L ++   RQ RL  AH  Q F RDA +
Sbjct: 41   VNTLAEQLVTD-GHPEEETIRQKQEEVNEAWKRLRQLSLLRQERLYGAHEIQRFNRDADE 217

Query: 1184 AEGVLSSQEYVLSHTEMPGTLQAADAAIKKLEDFMSTMDANGERIRGLLEAGRQLVSKGN 1243
                +  ++ VLS  +    L +     +K E     + A  E++  L   G + V    
Sbjct: 218  TIAWIQEKDAVLSTDDYGRDLASVQTLQRKHEGVERDLAALEEKVNAL---GTESVRLQG 388

Query: 1244 IHAEK 1248
            IH ++
Sbjct: 389  IHGDQ 403

 Score = 37.4 bits (85), Expect = 0.080,   Method: Compositional matrix adjust.
 Identities = 17/59 (28%), Positives = 34/59 (57%)
 Frame = +2

Query: 2014 EVLVFGRDAGMAEAWLCSQEPLVRSAELGCTVDEVESLIKRHEAFQKSAVAWEERFSAL 2072
            E+  F RDA    AW+  ++ ++ + + G  +  V++L ++HE  ++   A EE+ +AL
Sbjct: 185  EIQRFNRDADETIAWIQEKDAVLSTDDYGRDLASVQTLQRKHEGVERDLAALEEKVNAL 361

 Score = 31.2 bits (69), Expect = 5.4,   Method: Compositional matrix adjust.
 Identities = 22/117 (18%), Positives = 55/117 (47%)
 Frame = +2

Query: 1637 LADYAQTIKQLAASSQDMIDHEHPESTRLTIRQAQVDKLYASLKELAGXXXXXXXXXXXX 1696
            L ++   + ++   ++ ++   HPE   +  +Q +V++ +  L++L+             
Sbjct: 11   LQNHEDKVVEVNTLAEQLVTDGHPEEETIRQKQEEVNEAWKRLRQLSLLRQERLYGAHEI 190

Query: 1697 XXXXXXXDDLEQWIQEREVVAASHELGQDYEHVTMLRDKFREFSKDTSTIGQERVDS 1753
                   D+   WIQE++ V ++ + G+D   V  L+ K     +D + + +E+V++
Sbjct: 191  QRFNRDADETIAWIQEKDAVLSTDDYGRDLASVQTLQRKHEGVERDLAAL-EEKVNA 358

 Score = 31.2 bits (69), Expect = 5.7,   Method: Compositional matrix adjust.
 Identities = 17/59 (28%), Positives = 33/59 (55%)
 Frame = +2

Query: 755 DANDMEAWLVDALRLVSSPEVGHDEFSTQALARQHRALEEEIRAHRPTLDALREQAAAL 813
           DA++  AW+ +   ++S+ + G D  S Q L R+H  +E ++ A    ++AL  ++  L
Sbjct: 206 DADETIAWIQEKDAVLSTDDYGRDLASVQTLQRKHEGVERDLAALEEKVNALGTESVRL 382
>29446
          Length = 1445

 Score = 74.3 bits (181), Expect = 5e-13,   Method: Compositional matrix adjust.
 Identities = 50/138 (36%), Positives = 68/138 (49%), Gaps = 5/138 (3%)
 Frame = +3

Query: 58   VQKKTFTKWVNSHLARVTCRVGDLYSXXXXXXXXXXXXEVLSGETLPKPTK-GRMRIHCL 116
            +QK TFT+W N HL  V   + DL S            EVLSG+      K    R   L
Sbjct: 999  IQKNTFTRWANEHLRTVNKAIADLESDFSDGLRLVALIEVLSGKKFKHVNKRPNFRTQKL 1178

Query: 117  ENVDKALQFLK-EQKVHLENMGSHDIVDGNHRLTLGLVWTIILRFQIQDISVETEDNKEK 175
            ENV   L+FL+ ++ + + N+ S DIVD   +L LGL+WT+IL + I     E E+    
Sbjct: 1179 ENVTLTLKFLEDDEGIRIVNIDSTDIVDKKLKLILGLIWTLILHYSISMPMWEGEEPTPS 1358

Query: 176  K---SAKDALLLWCQMKT 190
            +   + K  LL W Q K 
Sbjct: 1359 EGGPTPKQRLLNWIQSKV 1412
>34417
          Length = 1096

 Score = 66.6 bits (161), Expect = 1e-10,   Method: Composition-based stats.
 Identities = 31/81 (38%), Positives = 48/81 (59%), Gaps = 1/81 (1%)
 Frame = +2

Query: 201 FTTSWRDGLAFNAIVHKHRPDLLDFESLKKCNAHYNLQNAFNLAEKELGLTKLLDPED-V 259
            ++ W +GLAF A++H   PD  D+  L+  N  YN + AF+ AEK   ++ LLD ED +
Sbjct: 35  LSSCWNNGLAFCALIHHFYPDAFDYSQLQPQNRRYNFELAFDTAEKLADISPLLDVEDMI 214

Query: 260 NVDQPDEKSIITYVATYYHYF 280
            +  PD K + TYV ++Y + 
Sbjct: 215 KMKNPDWKCVFTYVQSFYRHL 277
>11159
          Length = 520

 Score = 65.9 bits (159), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 40/120 (33%), Positives = 59/120 (49%), Gaps = 11/120 (9%)
 Frame = +2

Query: 2241 RSWQNVYCVLRRGSLGFYKD---ARAASAGVPYHGEVPVSLARAQGSVAFDYRKRKHVFK 2297
            RSW+  +  LR   L  +KD    R +      H  + +  A A  ++A DY K++HVF+
Sbjct: 65   RSWKMFFITLRDLVLYLHKDEHGFRKSQMSDNLHNAIRIHHALA--TMANDYTKKQHVFR 238

Query: 2298 LGLQDGKEYLFQAKDEAEMSSWLRVVNAAIATASSAPGES--------EEPVVPSASRGL 2349
            L   D  EYLFQ  D  E+ SW+  +N   A  S+ P E+        + P++PSA   L
Sbjct: 239  LQTADQAEYLFQTSDSKELHSWVETINYVCAAFSAPPLEAGVGSQKRFQRPLLPSAQTKL 418
>19246
          Length = 440

 Score = 65.9 bits (159), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 36/91 (39%), Positives = 51/91 (56%), Gaps = 2/91 (2%)
 Frame = +2

Query: 2235 NKKAANRSWQNVYCVLRRGSLGFYKDARAASAGVPYHGE-VPVSLARAQGSVAFDY-RKR 2292
             KK ++RSW+ V+ VLR  +L   KD R  S    +  E  P+S+      +A DY RKR
Sbjct: 44   GKKCSDRSWKQVWAVLRGHALFLIKDRRDGSTHPTFSFEEPPISIKSCLVDIAHDYSRKR 223

Query: 2293 KHVFKLGLQDGKEYLFQAKDEAEMSSWLRVV 2323
            KHVF+L       YL QA+D+  M SW++ +
Sbjct: 224  KHVFRLTTYSESVYLLQAEDKGTMMSWIQAI 316
>25051
          Length = 1017

 Score = 64.7 bits (156), Expect = 4e-10,   Method: Compositional matrix adjust.
 Identities = 50/145 (34%), Positives = 67/145 (46%), Gaps = 5/145 (3%)
 Frame = -2

Query: 2195 PQSRSSEAAHGATLPTRG-PELSAQ-EQMEGMLCRKQEMEAFNKKA--ANRSWQNVYCVL 2250
            P S S+ +  GA  P    P+ S   E  +G + RK  ME   +K     R W+ VY +L
Sbjct: 992  PPSTSAMSHLGAANPFLDVPDPSKTVEYKKGYVMRKSCMEPGRRKTPFGKRGWRMVYTIL 813

Query: 2251 RRGSLGFYKDARAASAG-VPYHGEVPVSLARAQGSVAFDYRKRKHVFKLGLQDGKEYLFQ 2309
            R   L  YKD      G      +  V +  A  + A DY K++HVF+L   D  EYLFQ
Sbjct: 812  RDLILYQYKDEHQVKKGQFVESSQNVVRIHHALATKASDYTKKQHVFRLQTADWAEYLFQ 633

Query: 2310 AKDEAEMSSWLRVVNAAIATASSAP 2334
                 E+  W+  +N   AT SS P
Sbjct: 632  TGGTIELQEWIDTINLVAATLSSPP 558
>38533
          Length = 380

 Score = 55.8 bits (133), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 42/118 (35%), Positives = 55/118 (46%), Gaps = 7/118 (5%)
 Frame = +1

Query: 1497 VEDEILWVT-ERLPMASSLEHGKDLPSVQLLMKKNQTLQKEIQGHEPRI------ADLKE 1549
            VEDE+ W   +R P+A S + G  L +VQ LMKK+Q L+ EI  HEP I      A    
Sbjct: 1    VEDELSWYY*DRKPIAESTDLGNSLTAVQNLMKKHQALESEIVAHEPLIDAVATSAQQMI 180

Query: 1550 RQRTLGTAAAGPELAELQEMWKRLSHELELRGKRLEEALRAQQFYRDAAEAEAWMGEQ 1607
            R +   TA     L +L    +R      L          AQ+FY +  E E WM E+
Sbjct: 181  RTKHFATADIQTRLDDLTSPAQRSQVFYLL*KVETAGCFGAQKFYMEVNEVELWMNEK 354

 Score = 34.7 bits (78), Expect = 0.43,   Method: Compositional matrix adjust.
 Identities = 16/42 (38%), Positives = 26/42 (61%)
 Frame = +1

Query: 769 LVSSPEVGHDEFSTQALARQHRALEEEIRAHRPTLDALREQA 810
           +  S ++G+   + Q L ++H+ALE EI AH P +DA+   A
Sbjct: 43  IAESTDLGNSLTAVQNLMKKHQALESEIVAHEPLIDAVATSA 168
>22703
          Length = 906

 Score = 55.5 bits (132), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 30/112 (26%), Positives = 57/112 (50%)
 Frame = -3

Query: 1963 FSSCIDMGQELLARSHYAAEEISEKLSQLQSRRQETADKWQEKMDWLQLVLEVLVFGRDA 2022
            F      G+  +A  H+ ++EI EK+ QL    +      + +    Q  LE      + 
Sbjct: 880  FDKFRKTGRSFIANGHFLSKEIEEKIKQLDQSLEGLIRNLEHRRKLHQQNLEAQQLRHEM 701

Query: 2023 GMAEAWLCSQEPLVRSAELGCTVDEVESLIKRHEAFQKSAVAWEERFSALEK 2074
               EAW+  +EPL++  + G +++  E +++RH+ F K+  A E+R +AL++
Sbjct: 700  EQIEAWMNLREPLLKEKKFGESIEGAEEMLRRHD*F*KTVTAQEDRVNALQR 545
>29517
          Length = 622

 Score = 52.8 bits (125), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 33/81 (40%), Positives = 39/81 (48%), Gaps = 4/81 (4%)
 Frame = -1

Query: 2280 RAQGS----VAFDYRKRKHVFKLGLQDGKEYLFQAKDEAEMSSWLRVVNAAIATASSAPG 2335
            RA GS     A DY KR +VF+L L  G EYLFQAKD AE  +W+  +N+          
Sbjct: 619  RAAGSQL*GWAADYSKRPYVFRLKLSSGSEYLFQAKDAAERDTWIGRINSVTG------- 461

Query: 2336 ESEEPVVPSASRGLTRAMTMP 2356
               EP    A R    A T P
Sbjct: 460  -GREPAFRLAHRRCXHAQTTP 401
>17567
          Length = 448

 Score = 48.1 bits (113), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 32/137 (23%), Positives = 68/137 (49%)
 Frame = -3

Query: 536 VFQDLLYLMDWMAEMKGRLQSQDLGKHLAGVEDLLQLHELVEADIAVQAERVRAVSASAL 595
           +F+++  + + + E++ ++  +D GKHL   +D+L+ H L EA +     RVR ++    
Sbjct: 383 MFREIESIQEELKEVQSKVVGEDYGKHLQATQDMLEQHSLQEAQLQALTRRVRKLN---- 216

Query: 596 RFCDPGKEYRPCDPQLVSERVATLEQSYEALCELAATRRARLEESRRLWRFLWEVGEAEA 655
                 ++ +    Q + +R+  L      +   +  RR  LE +++ ++FL +  E + 
Sbjct: 215 ------RKSQGAQEQSLDKRLEALNAQLNNVQAQSDKRRQGLETAQQYYQFLQDTEEEDR 54

Query: 656 WVREQQHLLASADTGRD 672
           WV E+   + S   G+D
Sbjct: 53  WVGERIDAVRSPSLGKD 3
>04951
          Length = 2852

 Score = 47.8 bits (112), Expect = 6e-05,   Method: Composition-based stats.
 Identities = 50/173 (28%), Positives = 84/173 (48%), Gaps = 14/173 (8%)
 Frame = +1

Query: 116 LENVDKALQF---LKEQKVHLENMGSHDIVDGNHRLTLGLVWTIILRFQIQDISVETEDN 172
           +EN + A+Q    +K  K+ L  +G  DI DGN  LTLGLVW ++  + +  +S  TED 
Sbjct: 7   IENCEYAVQLGPQMKVCKMKLVGIGGKDIHDGNPVLTLGLVWQLMRAYTLAILSKLTED- 183

Query: 173 KEKKSAKDALLL-WCQMKTAGYPNVNVHNFTTS-WRDGLAFNAIVHKHRPDLLDFESL-- 228
             KK  +D+ ++ W   K     +  + +F  S   DG+    ++   +P ++++E++  
Sbjct: 184 --KKPIQDSEIVDWVNSKVK--KDERIGSFQDSKLNDGVIVAKVIESIKPGIVNWENINP 351

Query: 229 -------KKCNAHYNLQNAFNLAEKELGLTKLLDPEDVNVDQPDEKSIITYVA 274
                  +  NA Y    A  LA K +G      PED+   +P  K ++T  A
Sbjct: 352 NASEPDDRLANARY----AIGLARK-IGAGVYALPEDIVEVKP--KMLLTVFA 489
>09711
          Length = 3041

 Score = 47.0 bits (110), Expect = 9e-05,   Method: Compositional matrix adjust.
 Identities = 45/175 (25%), Positives = 85/175 (48%), Gaps = 15/175 (8%)
 Frame = +1

Query: 116  LENVDKALQF---LKEQKVHLENMGSHDIVDGNHRLTLGLVWTIILRFQIQDISVETEDN 172
            +EN + A++    +K  KV L  +   DI+DGN  LTLGLVW ++  + +  +S  TE+N
Sbjct: 1033 IENCNYAVELGPQVKLVKVKLVGIAGQDILDGNPVLTLGLVWQLMRAYTLAILSKITENN 1212

Query: 173  KEKKSAKDALLLWCQMK------TAGYPNVNVHNFTTSWRDGLAFNAIVHKHRPDLLDFE 226
              K  + + ++ W   K       +G+ +  ++       DG+    ++   +P +++++
Sbjct: 1213 --KPISDNEIITWVNSKIKKDDRISGFQDRKLN-------DGVIVARVIEAIKPGIVNWD 1365

Query: 227  SLKKCNAH------YNLQNAFNLAEKELGLTKLLDPEDVNVDQPDEKSIITYVAT 275
            ++  C+A        N + A  LA K +G      PED+   +P  K ++T  A 
Sbjct: 1366 NI-DCSARDYQDRLTNARYAIGLARK-IGAGVYALPEDIVEVKP--KMLLTVFAC 1518
>09100
          Length = 930

 Score = 36.6 bits (83), Expect = 0.14,   Method: Compositional matrix adjust.
 Identities = 24/110 (21%), Positives = 47/110 (42%), Gaps = 7/110 (6%)
 Frame = +1

Query: 59  QKKTFTKWVNSHLARVTCR--VGDLYSXXXXXXXXXXXXEVLSGETLP-----KPTKGRM 111
           Q   +  W+NS L +      + DL               ++S + +P       T   M
Sbjct: 463 QLSAYMAWINSQLKKKPGAHLIEDLRHDMRDGVVFADVIHIVSKQQIPGIQNVPTTLDEM 642

Query: 112 RIHCLENVDKALQFLKEQKVHLENMGSHDIVDGNHRLTLGLVWTIILRFQ 161
           R    +NVD+ L F+ + ++ +  + S DIV+GN +  + L+  +   ++
Sbjct: 643 R----QNVDRVLHFMTQNRIKMHRISSRDIVEGNLKAVMRLILALAAHYK 780
>29667
          Length = 466

 Score = 34.7 bits (78), Expect = 0.50,   Method: Composition-based stats.
 Identities = 15/39 (38%), Positives = 25/39 (64%)
 Frame = +1

Query: 2292 RKHVFKLGLQDGKEYLFQAKDEAEMSSWLRVVNAAIATA 2330
            + HVFKL  ++   Y F+A+ E   S W+ V+N+A ++A
Sbjct: 91   KDHVFKLQFKN-HVYFFRAESEYTYSRWMEVINSATSSA 204
>32371
          Length = 625

 Score = 33.9 bits (76), Expect = 0.72,   Method: Composition-based stats.
 Identities = 12/25 (48%), Positives = 19/25 (76%)
 Frame = -1

Query: 195 NVNVHNFTTSWRDGLAFNAIVHKHR 219
           +V++ +   SWR+GLAF AI+H+ R
Sbjct: 625 SVDIKDLLVSWRNGLAFCAIIHRFR 551
>18202
          Length = 424

 Score = 32.7 bits (73), Expect = 1.7,   Method: Composition-based stats.
 Identities = 19/62 (30%), Positives = 31/62 (50%), Gaps = 6/62 (9%)
 Frame = -1

Query: 132 HLENMG------SHDIVDGNHRLTLGLVWTIILRFQIQDISVETEDNKEKKSAKDALLLW 185
           H++N G      + DI+DG+ +  L ++W +IL + I  I       +   + K  LL W
Sbjct: 193 HMKNHGIKIVFSTQDIMDGDIKSLLDVMWLLILNYGIHFIG-NNSFQRSVGAGKKNLLDW 17

Query: 186 CQ 187
           CQ
Sbjct: 16  CQ 11
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6679501|ref|NP_032973.1| protease (prosome,
macropain) 26S subunit, ATPase 1 [Mus musculus]
         (440 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

23766                                                                 428   e-120
01642                                                                 337   e-106
07243                                                                 305   3e-83
19129                                                                 298   3e-81
07247                                                                 223   2e-67
02582                                                                 176   2e-44
03022                                                                 154   5e-38
12235                                                                 152   3e-37
00810                                                                 112   3e-25
20270                                                                 110   2e-24
38672                                                                  85   3e-23
25671                                                                  83   3e-16
02194                                                                  75   4e-14
26408                                                                  75   5e-14
26887                                                                  73   3e-13
17843                                                                  58   9e-09
06766                                                                  44   1e-04
14413                                                                  44   1e-04
01102                                                                  40   0.003
01279                                                                  36   0.035
29846                                                                  36   0.036
27434                                                                  33   0.15 
13641                                                                  33   0.19 
30736                                                                  32   0.74 
37695                                                                  31   0.88 
19561                                                                  30   2.1  
38684                                                                  29   3.2  
02151                                                                  28   5.3  
>23766
          Length = 1463

 Score =  428 bits (1101), Expect = e-120,   Method: Compositional matrix adjust.
 Identities = 207/226 (91%), Positives = 217/226 (96%)
 Frame = +1

Query: 215 GIKPPKGVILYGPPGTGKTLLAKAVANQTSATFLRVVGSELIQKYLGDGPKLVRELFRVA 274
           G + PKGVILYGPPGTGKTLLAKAVANQTSATFLRVVGSELIQKYLGDGPKLVRELFRVA
Sbjct: 142 GNQAPKGVILYGPPGTGKTLLAKAVANQTSATFLRVVGSELIQKYLGDGPKLVRELFRVA 321

Query: 275 EEHAPSIVFIDEIDAIGTKRYDSNSGGEREIQRTMLELLNQLDGFDSRGDVKVIMATNRI 334
           EEHAPSIVFIDEIDA+GTKRY+SNSGGEREIQRTMLELLNQLDGFDSRGDVKVIMATNRI
Sbjct: 322 EEHAPSIVFIDEIDAVGTKRYESNSGGEREIQRTMLELLNQLDGFDSRGDVKVIMATNRI 501

Query: 335 ETLDPALIRPGRIDRKIEFPLPDEKTKKRIFQIHTSRMTLADDVTLDDLIMAKDDLSGAD 394
           ETLDPALIRPGRIDRKIEFPLPDEKTK+RIF IHTSRMTLA DV +DD +M+KDDLSGAD
Sbjct: 502 ETLDPALIRPGRIDRKIEFPLPDEKTKRRIFTIHTSRMTLAGDVNIDDYVMSKDDLSGAD 681

Query: 395 IKAICTEAGLMALRERRMKVTNEDFKKSKENVLYKKQEGTPEGLYL 440
           IKAICTEAGL+ALRERRMKV NEDF K+KENVLY+K EGTPEGLYL
Sbjct: 682 IKAICTEAGLLALRERRMKVRNEDFAKAKENVLYRKNEGTPEGLYL 819

 Score = 96.7 bits (239), Expect = 2e-20,   Method: Compositional matrix adjust.
 Identities = 51/80 (63%), Positives = 55/80 (68%), Gaps = 1/80 (1%)
 Frame = +2

Query: 169 PLVTVMK-VEKAPQETYADIGGLDNQIQEIKESVELPLTHPEYYEEMGIKPPKGVILYGP 227
           P+VTVMK  EKAPQETYADIGGLD QIQEIKESVELPLTHPEYYEEMGIK  K +   G 
Sbjct: 2   PMVTVMKGWEKAPQETYADIGGLDTQIQEIKESVELPLTHPEYYEEMGIKHQKVLSCMGL 181

Query: 228 PGTGKTLLAKAVANQTSATF 247
               K    K +  +    F
Sbjct: 182 QAQAKPCWPKLLPTRPRRLF 241
>01642
          Length = 1406

 Score =  337 bits (863), Expect(2) = e-106,   Method: Compositional matrix adjust.
 Identities = 152/257 (59%), Positives = 208/257 (80%)
 Frame = -1

Query: 173  VMKVEKAPQETYADIGGLDNQIQEIKESVELPLTHPEYYEEMGIKPPKGVILYGPPGTGK 232
              K+ ++P   Y+DIGG+D Q QE++E+VELPLTH E Y+++GI PP+GV++YGPPG GK
Sbjct: 1031 CFKLMRSPT*XYSDIGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGVLMYGPPGCGK 852

Query: 233  TLLAKAVANQTSATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPSIVFIDEIDAIGT 292
            T+LAKAVA+ T+A F+RVVGSE +QKYLG+GP++VR++FR+A+E+AP+I+FIDEIDAI T
Sbjct: 851  TMLAKAVAHHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEIDAIAT 672

Query: 293  KRYDSNSGGEREIQRTMLELLNQLDGFDSRGDVKVIMATNRIETLDPALIRPGRIDRKIE 352
            KR+D+ +G +RE+QR +LELLNQ+DGFD   +VKVIMATNR +TLDPAL+RPGR+DRKIE
Sbjct: 671  KRFDAQTGADREVQRILLELLNQMDGFDQTVNVKVIMATNRADTLDPALLRPGRLDRKIE 492

Query: 353  FPLPDEKTKKRIFQIHTSRMTLADDVTLDDLIMAKDDLSGADIKAICTEAGLMALRERRM 412
            FPLPD + K+ IF   T +M ++++V L+D +   D +SGADI AIC EAG+ A+RE R 
Sbjct: 491  FPLPDRRQKRLIFSTITGKMNISEEVDLEDYVARPDKISGADINAICQEAGMQAVRENRY 312

Query: 413  KVTNEDFKKSKENVLYK 429
             V  +DF+K  +N + K
Sbjct: 311  VVLAKDFEKGYKNNIKK 261

 Score = 66.2 bits (160), Expect(2) = e-106,   Method: Compositional matrix adjust.
 Identities = 37/114 (32%), Positives = 69/114 (60%)
 Frame = -2

Query: 50   PLVTPHTQCRLKLLKLERIKDYLLMEEEFIRNQEQMKPLEEKQEEERSKVDDLRGTPMSV 109
            PL        +K  KL+R  ++L ++EE+I++++  K L+++    + +V  ++  P+ +
Sbjct: 1396 PLSLDVEDLYVKYKKLQRQLEFLEVQEEYIKDEQ--KNLKKEYLHAQEEVKRIQSVPLVI 1223

Query: 110  GTLEEIIDDNHAIVSTSVGSEHYVSILSFVDKDLLEPGCSVLLNHKVHAVIGVL 163
            G   E +D N  IV ++ GS +YV ILS +D++LL+P  SV L+   +A++ VL
Sbjct: 1222 GQFLEAVDQNTGIVGSTTGSNYYVRILSTIDRELLKPSSSVALHKHSNALVDVL 1061
>07243
          Length = 1112

 Score =  305 bits (781), Expect = 3e-83,   Method: Compositional matrix adjust.
 Identities = 148/305 (48%), Positives = 206/305 (67%)
 Frame = +1

Query: 122 IVSTSVGSEHYVSILSFVDKDLLEPGCSVLLNHKVHAVIGVLMDDTDPLVTVMKVEKAPQ 181
           IV  + G  + V     +DK  L+ G  V L+     ++  L  + DPLV  M  E    
Sbjct: 16  IVKATNGPRYVVGCRRQLDKAKLKSGTRVALDMTTLTIMRYLPREVDPLVYNMSHEDPGD 195

Query: 182 ETYADIGGLDNQIQEIKESVELPLTHPEYYEEMGIKPPKGVILYGPPGTGKTLLAKAVAN 241
            TY+ IGGL  QI+E++E +ELPL +PE +  +GI PPKG +LYGPPGTGKTLLA+AVA+
Sbjct: 196 VTYSAIGGLTEQIRELREVIELPLLNPELFLRVGITPPKGCLLYGPPGTGKTLLARAVAS 375

Query: 242 QTSATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPSIVFIDEIDAIGTKRYDSNSGG 301
           Q  A FL+VV S ++ KY+G+  +L+RE+F  A +H P I+F+DEIDAIG +R+   +  
Sbjct: 376 QLDANFLKVVSSAIVDKYIGESARLIREMFNYARDHQPCIIFMDEIDAIGGRRFSEGTSA 555

Query: 302 EREIQRTMLELLNQLDGFDSRGDVKVIMATNRIETLDPALIRPGRIDRKIEFPLPDEKTK 361
           +REIQRT++ELLNQ+DGFDS G VK+IMATNR +TLDPAL+RPGR+DRKIE PLP+E+ +
Sbjct: 556 DREIQRTLMELLNQMDGFDSLGQVKMIMATNRPDTLDPALLRPGRLDRKIEIPLPNEQAR 735

Query: 362 KRIFQIHTSRMTLADDVTLDDLIMAKDDLSGADIKAICTEAGLMALRERRMKVTNEDFKK 421
             I +IH   +    ++  + ++   D+ +GAD++ +CTEAGL A+R  R  V  EDF K
Sbjct: 736 LEILKIHALIIAKHGEIDYEAIVKLSDNFNGADLRNVCTEAGLFAIRAEREYVIQEDFMK 915

Query: 422 SKENV 426
           +   V
Sbjct: 916 AVRKV 930
>19129
          Length = 1020

 Score =  298 bits (764), Expect = 3e-81,   Method: Compositional matrix adjust.
 Identities = 155/310 (50%), Positives = 214/310 (69%), Gaps = 14/310 (4%)
 Frame = +1

Query: 66  ERIKDYLLM---EEEFIRNQ--EQMKPLEEKQEEERSKVDDLR---------GTPMSVGT 111
           E IK Y +    E++ I N+  + ++ LE ++ E  +KV  LR         G+   VG 
Sbjct: 94  EGIKQYYISKIEEQQLIVNEKTQNLRRLEAQRNELNAKVRMLREELQLLQEQGS--YVGE 267

Query: 112 LEEIIDDNHAIVSTSVGSEHYVSILSFVDKDLLEPGCSVLLNHKVHAVIGVLMDDTDPLV 171
           + + +D    +V      +  V I   +D + + P C V L +  + +  +L +  DPLV
Sbjct: 268 VVKPMDKKKVLVKVHPEGKFVVDIDKNIDMNSVTPNCRVALRNDSYVLHKILPNKVDPLV 447

Query: 172 TVMKVEKAPQETYADIGGLDNQIQEIKESVELPLTHPEYYEEMGIKPPKGVILYGPPGTG 231
           ++M VEK P  TY  +GGLD QI+EIKE +ELP+ HPE +E +GI  PKGV+LYGPPGTG
Sbjct: 448 SLMMVEKVPDSTYEMVGGLDKQIKEIKEVIELPVKHPELFEALGIAQPKGVLLYGPPGTG 627

Query: 232 KTLLAKAVANQTSATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPSIVFIDEIDAIG 291
           KTLLA+AVA+ T  TF+RV GSEL+QK++G+G ++VRELF +A EHAPSI+F+DEID+IG
Sbjct: 628 KTLLARAVAHHTECTFIRVSGSELVQKFIGEGSRMVRELFVMAREHAPSIIFMDEIDSIG 807

Query: 292 TKRYDSNSGGEREIQRTMLELLNQLDGFDSRGDVKVIMATNRIETLDPALIRPGRIDRKI 351
           + R +  SGG+ E+QRTMLELLNQLDGF+ + ++KVIMATNRI+ LD AL+RPGRIDRKI
Sbjct: 808 SSRLEGGSGGDSEVQRTMLELLNQLDGFEPKQNIKVIMATNRIDILDSALLRPGRIDRKI 987

Query: 352 EFPLPDEKTK 361
           EFP P+E+ +
Sbjct: 988 EFPPPNEEAR 1017
>07247
          Length = 1753

 Score =  223 bits (569), Expect(2) = 2e-67,   Method: Compositional matrix adjust.
 Identities = 102/204 (50%), Positives = 147/204 (72%)
 Frame = -2

Query: 228  PGTGKTLLAKAVANQTSATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPSIVFIDEI 287
            PGTGKTLLA+AVA+Q    FL+VV S ++ KY+G+  +L+RE+F  A +H P I+F+DEI
Sbjct: 1407 PGTGKTLLARAVASQLDCNFLKVVSSAIVDKYIGESARLIREMFAFARDHEPCIIFMDEI 1228

Query: 288  DAIGTKRYDSNSGGEREIQRTMLELLNQLDGFDSRGDVKVIMATNRIETLDPALIRPGRI 347
            DAIG +R+   +  +REIQRT++ELLNQ+DGFD+ G VK+IMATNR +TLDPAL+RPGR+
Sbjct: 1227 DAIGGRRFSEGTSADREIQRTLMELLNQMDGFDALGQVKMIMATNRPDTLDPALLRPGRL 1048

Query: 348  DRKIEFPLPDEKTKKRIFQIHTSRMTLADDVTLDDLIMAKDDLSGADIKAICTEAGLMAL 407
            DRKIE  LP+E+ +  I +IH + +    ++  + ++   +D +GAD++ +CTEAG+ A+
Sbjct: 1047 DRKIEISLPNEQARLEILKIHANPIAKHGEIDWEAVVKLSEDFNGADLRNVCTEAGMFAI 868

Query: 408  RERRMKVTNEDFKKSKENVLYKKQ 431
            R  R  V  EDF K+   V   K+
Sbjct: 867  RAERDYVIEEDFMKAVRKVSDNKK 796

 Score = 50.8 bits (120), Expect(2) = 2e-67,   Method: Compositional matrix adjust.
 Identities = 25/65 (38%), Positives = 36/65 (55%)
 Frame = -1

Query: 163  LMDDTDPLVTVMKVEKAPQETYADIGGLDNQIQEIKESVELPLTHPEYYEEMGIKPPKGV 222
             +   DPLV  M VE     T+  IGGL  Q++E++E +ELPL +PE ++ +GI   K  
Sbjct: 1600 WISGMDPLVYNMSVEDPGDITFNQIGGLGEQVRELREVIELPLLNPELFQRVGITRLKAA 1421

Query: 223  ILYGP 227
                P
Sbjct: 1420 CCSDP 1406
>02582
          Length = 1101

 Score =  176 bits (445), Expect = 2e-44,   Method: Compositional matrix adjust.
 Identities = 107/268 (39%), Positives = 149/268 (55%), Gaps = 33/268 (12%)
 Frame = +3

Query: 184 YADIGGLDNQIQEIKESVELPLTHPEYYEEMGIKPPKGVILYGPPGTGKTLLAKAVANQT 243
           + DIGGLD    +I+++VE PL +P+ ++ +G+   KGV+LYGPPG GKT LA+A A   
Sbjct: 138 WTDIGGLDLVKLQIRQAVEWPLLYPDTFQALGLPLTKGVLLYGPPGCGKTTLAQAAATAC 317

Query: 244 SATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPSIVFIDEIDAIGTKRYDSNSGGER 303
             TFL +  ++L   Y+GD  K + E F+ A   APSI+F+DE+DAI  KR DS+ G   
Sbjct: 318 HVTFLSLSCAQLYSPYVGDAEKKISETFQKARALAPSILFLDEMDAIVGKRSDSSLGSGV 497

Query: 304 EIQRTMLELLNQLDGFDSRGD--------------------------------VKVIMAT 331
             +R +  LLN++DG   R D                                V V+ AT
Sbjct: 498 S-ERVLSALLNEMDGIGVRLDDKSDSREMEIEGSSDHTPQVRQHAVKEAHDRHVLVVAAT 674

Query: 332 NRIETLDPALIRPGRIDRKIEFPLPDEKTKKRIFQIHTSRMTLADDVTLDDLIMAKDDLS 391
           NR + LDPAL+RPGR+DR I  P PD + + + F IHT +M L  DV +  L       +
Sbjct: 675 NRPDMLDPALLRPGRMDRLIYVPPPDVQGRLQSFTIHTRKMPLGKDVDVKQLADLTAGYT 854

Query: 392 GADIKAICTEAGLMALRER-RMKVTNED 418
           GADIK +C E GL+AL+E    +  N+D
Sbjct: 855 GADIKTLCNEVGLLALKESMSAECVNQD 938
>03022
          Length = 2255

 Score =  154 bits (390), Expect = 5e-38,   Method: Compositional matrix adjust.
 Identities = 89/232 (38%), Positives = 130/232 (56%), Gaps = 2/232 (0%)
 Frame = +2

Query: 180  PQETYADIGGLDNQIQEIKESVELPLTHPEYYEEMGIKPPKGVILYGPPGTGKTLLAKAV 239
            P  T+ D+G L N   ++K+S+   +  PE     G+    G+IL GPPG GKTL+AKA+
Sbjct: 1412 PTTTWEDVGALSNVRAQLKDSILCRIHDPEVSSAFGLPTNSGIILVGPPGCGKTLVAKAM 1591

Query: 240  ANQTSATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPSIVFIDEIDAIGTKRYDSNS 299
            AN+    F+ + G EL+ KY+G+  + +RE F  A+  AP ++F DE+D + + R   N+
Sbjct: 1592 ANEAGLNFIYIKGPELLDKYVGESERNLREKFDKAQACAPCLIFFDEMDTLCSNR--QNN 1765

Query: 300  GGEREIQRTMLELLNQLDGFDSRGDVKVIMATNRIETLDPALIRPGRIDRKIEFPLPDEK 359
             G    +    +LL  +DG   R  V V+ ATN IE +DPAL RPGR DRKI   LPD  
Sbjct: 1766 DGSNVGKSVTNQLLALMDGCGERSQVYVMGATNIIENVDPALQRPGRFDRKIFIGLPDTD 1945

Query: 360  TKKRIFQIHTSRMTLADDVTLDDLIMAKD--DLSGADIKAICTEAGLMALRE 409
             +  I +  T   +     + D   +A+D    SGAD+K +  EA  +AL+E
Sbjct: 1946 GRLDILRALTKGGSQRKLESCDMQQLAQDTEGFSGADLKHLVNEASTIALKE 2101

 Score = 58.9 bits (141), Expect(2) = 2e-14,   Method: Compositional matrix adjust.
 Identities = 34/117 (29%), Positives = 58/117 (49%), Gaps = 2/117 (1%)
 Frame = +1

Query: 180 PQETYADIGGLDNQIQEIKESVE--LPLTHPEYYEEMGIKPPKGVILYGPPGTGKTLLAK 237
           P  T  D GG +  + E+    E  L   + +Y      K  +  +LYGP G+GK  LA+
Sbjct: 514 PTATLDDFGGSNKLLAELDSDFEEILYSDYCQYASACDQKACRRYLLYGPRGSGKRFLAE 693

Query: 238 AVANQTSATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPSIVFIDEIDAIGTKR 294
            +A Q     L+   + LI    GD  + VR+LF  A   AP ++++++I+ +  ++
Sbjct: 694 CIAGQLKLPLLKPKINTLISGVSGDSEQRVRDLFDQAVSQAPCVLYLEDIECLAPRQ 864

 Score = 37.7 bits (86), Expect(2) = 2e-14,   Method: Compositional matrix adjust.
 Identities = 33/114 (28%), Positives = 54/114 (47%), Gaps = 2/114 (1%)
 Frame = +2

Query: 300 GGEREIQ-RTMLELLNQLDGFDSRG-DVKVIMATNRIETLDPALIRPGRIDRKIEFPLPD 357
           GG +++  R + EL + +D    +  +V V+  T+RIE +   L  PGR   K    +PD
Sbjct: 875 GGSKDMMTRIVSELGSCIDELQEKPENVVVVATTSRIEAVHRDLRIPGRFMEK-ALGMPD 1051

Query: 358 EKTKKRIFQIHTSRMTLADDVTLDDLIMAKDDLSGADIKAICTEAGLMALRERR 411
           E +++ + Q   SR TL+  + L  L          D++A+   A   A R  R
Sbjct: 1052EGSREGLLQRLCSRYTLSPHLKLKTLARLTPGFVAGDLRALVHGAFSTAFRRVR 1213
>12235
          Length = 1749

 Score =  152 bits (383), Expect = 3e-37,   Method: Compositional matrix adjust.
 Identities = 79/190 (41%), Positives = 120/190 (63%), Gaps = 4/190 (2%)
 Frame = +1

Query: 242 QTSATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPSIVFIDEIDAIGTKRYDSNSGG 301
           + +  F+ V GSE ++ ++G GP  VR++F  A ++AP I+F+DEIDA+G KR   N GG
Sbjct: 1   EANVPFITVSGSEFLEMFVGVGPSRVRDMFATARKNAPCILFVDEIDAVGRKRSGRNFGG 180

Query: 302 EREIQRTMLELLNQLDGFDSRGDVKVIMATNRIETLDPALIRPGRIDRKIEFPLPDEKTK 361
           + E + T+ +LL ++DGF+++  V V+ ATNR++ LD AL+RPGR DR+I  PLPD K +
Sbjct: 181 QSEQENTLNQLLVEMDGFNTQTGVVVLAATNRVDILDAALLRPGRFDRQIFVPLPDIKXR 360

Query: 362 KRIFQIHTSRMTLADDVTLDDLI--MAK--DDLSGADIKAICTEAGLMALRERRMKVTNE 417
             IF++H     L  +V  +DL   MA      SGADI  +C EA L+A R+    +   
Sbjct: 361 ASIFKVHLD--PLKTEVNKNDLARKMAALTPGFSGADIANVCNEAALIAARDLNTSIHMT 534

Query: 418 DFKKSKENVL 427
            F+++ E V+
Sbjct: 535 HFEQAIERVV 564
>00810
          Length = 1431

 Score =  112 bits (280), Expect = 3e-25,   Method: Compositional matrix adjust.
 Identities = 72/223 (32%), Positives = 123/223 (55%), Gaps = 3/223 (1%)
 Frame = -3

Query: 190  LDNQIQEIKESVELPLTHPEYYEEMGI-KPPKGVILYGPPGTGKTLLAKAVANQTSATFL 248
            L++ IQ++KE+V LP    + +    + +PPKGV+L+GPPG GKT++AKA A    A F+
Sbjct: 1429 LEDVIQDVKETVILPFKRADLFRHSSLLQPPKGVLLHGPPGCGKTMIAKATAKAAGARFI 1250

Query: 249  RVVGSELIQKYLGDGPKLVRELFRVAEEHAPSIVFIDEIDAIGTKRYDSNSGGEREIQRT 308
             +  S L+ K+ G+  K    +F +A +  P+I+FIDEID+    R  ++      I+  
Sbjct: 1249 NLQVSSLVDKWYGESQKRAEAVFSLAIKLQPTIIFIDEIDSFLRSRTSTDHEATAMIK-- 1076

Query: 309  MLELLNQLDGFDSRGDVKVIM--ATNRIETLDPALIRPGRIDRKIEFPLPDEKTKKRIFQ 366
              + ++  DG  +  D +V++  ATNR + +D A++R  R+       LP    ++ IF 
Sbjct: 1075 -TQFMSFWDGLMTDPDCRVMVMGATNRPQDVDAAILR--RMPSMFHIGLPGPAQRRSIFN 905

Query: 367  IHTSRMTLADDVTLDDLIMAKDDLSGADIKAICTEAGLMALRE 409
            +  S+  + D +  D+L    D  SG+DI+ +C  A +  + E
Sbjct: 904  LILSKERI-DALNYDELAEMTDGFSGSDIREVCRAAAVATVHE 779
>20270
          Length = 542

 Score =  110 bits (274), Expect = 2e-24,   Method: Compositional matrix adjust.
 Identities = 62/130 (47%), Positives = 87/130 (66%), Gaps = 3/130 (2%)
 Frame = -3

Query: 217 KPPKGVILYGPPGTGKTLLAKAVANQ-TSATFLRVVGSELIQKYLGDGPKLVRELFRVAE 275
           KP +G++LYGPPGTGK+ LAKAVA +  ++TF  V  S+L+ K+LG+  KLV+ LF++A 
Sbjct: 387 KPWRGILLYGPPGTGKSYLAKAVATEANNSTFFSVSSSDLVSKWLGESEKLVKTLFQLAR 208

Query: 276 EHAPSIVFIDEIDAIGTKRYDSNSGGEREIQRTMLELLNQLDGF--DSRGDVKVIMATNR 333
           E+ PSI+FIDE+DA+   R ++ S   R I+    E L Q+ G   D+ G V V+ ATN 
Sbjct: 207 ENQPSIIFIDEVDALCGSRSENESESARRIK---TEFLVQMQGVGNDNTG-VLVLGATNI 40

Query: 334 IETLDPALIR 343
             TLD A+ R
Sbjct: 39  PWTLDSAIRR 10
>38672
          Length = 730

 Score = 85.1 bits (209), Expect(2) = 3e-23,   Method: Compositional matrix adjust.
 Identities = 46/110 (41%), Positives = 66/110 (60%)
 Frame = -3

Query: 301 GEREIQRTMLELLNQLDGFDSRGDVKVIMATNRIETLDPALIRPGRIDRKIEFPLPDEKT 360
           GE E +R + +LL  +DG   R  V V+ ATNR  ++D AL R GR DR+++  +PD   
Sbjct: 599 GEVE-RRIVSQLLTLMDGLKQRSHVIVMAATNRPNSVDAALRRFGRFDREVDIGIPDATG 423

Query: 361 KKRIFQIHTSRMTLADDVTLDDLIMAKDDLSGADIKAICTEAGLMALRER 410
           +  I +IHT  M LADDV L+ +        GAD+ A+C+EA L  +RE+
Sbjct: 422 RLEILRIHTKNMKLADDVDLEQVASETHGHVGADVAALCSEAALQQIREK 273

 Score = 41.2 bits (95), Expect(2) = 3e-23,   Method: Compositional matrix adjust.
 Identities = 18/40 (45%), Positives = 28/40 (70%)
 Frame = -1

Query: 255 LIQKYLGDGPKLVRELFRVAEEHAPSIVFIDEIDAIGTKR 294
           ++ K  G+    +R+ F  AE++AP+I+FIDE+DAI  KR
Sbjct: 730 IMSKLAGESESNLRKAFEEAEKNAPAIIFIDELDAIAPKR 611

 Score = 48.1 bits (113), Expect = 7e-06,   Method: Compositional matrix adjust.
 Identities = 23/72 (31%), Positives = 40/72 (55%), Gaps = 7/72 (9%)
 Frame = -3

Query: 160 IGVLMDD-------TDPLVTVMKVEKAPQETYADIGGLDNQIQEIKESVELPLTHPEYYE 212
           + V MDD       ++P        + P  ++ D+GGL+N  +E++E V+ P+ HPE + 
Sbjct: 218 LAVTMDDFRWALGKSNPSALRETCVEVPNVSWEDVGGLENVKKELQELVQYPVEHPEKFL 39

Query: 213 EMGIKPPKGVIL 224
           + G+ P KGV+ 
Sbjct: 38  KFGMTPSKGVLF 3
>25671
          Length = 441

 Score = 82.8 bits (203), Expect = 3e-16,   Method: Composition-based stats.
 Identities = 52/109 (47%), Positives = 64/109 (58%), Gaps = 6/109 (5%)
 Frame = +2

Query: 230 TGKTLLAKAVANQTSATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPSIVFIDEIDA 289
           TGKT+LAKAVA +   TF  V  S L  KY G+  KLVR LF +A  +APS +FIDEID+
Sbjct: 2   TGKTMLAKAVATECGTTFFNVSTSSLANKYRGESEKLVRLLFEMAHFYAPSTIFIDEIDS 181

Query: 290 IGTKR-YDSNSGGEREIQRTMLELLNQLDGFDSRGD-----VKVIMATN 332
           I +KR  DS     R ++    ELL Q+DG     D     V V+ ATN
Sbjct: 182 ICSKRGSDSEHEASRRVKS---ELLVQMDGVGVTNDDPSKAVMVLAATN 319
>02194
          Length = 1891

 Score = 75.5 bits (184), Expect = 4e-14,   Method: Compositional matrix adjust.
 Identities = 57/148 (38%), Positives = 76/148 (51%), Gaps = 3/148 (2%)
 Frame = -1

Query: 206  THPEYYEEMGIKPPKGVILYGPPGTGKTLLAKAVANQTSATFLRVVGSELIQKYLGDGPK 265
            T P +Y + GI   +G +LYGPPG GK+    A+A    A    +    L +K L D   
Sbjct: 1537 TAPRWYMDRGIPYRRGYLLYGPPGCGKSSYIMALAG---ALDYNICVLNLSEKGLSD--D 1373

Query: 266  LVRELFRVAEEHAPSIVFIDEIDAIGTKRYDS--NSGGEREIQR-TMLELLNQLDGFDSR 322
             +  L  VA E   SI+ ++++DA    R  S  N    + + R T   LLN LDG  S 
Sbjct: 1372 RLNHLLTVAPEQ--SIILLEDVDAAFLSRDLSKENPAMYQGMGRLTFSGLLNALDGVASA 1199

Query: 323  GDVKVIMATNRIETLDPALIRPGRIDRK 350
                V M TN ++ LDPALIRPGR+D K
Sbjct: 1198 EARIVFMTTNYLDRLDPALIRPGRVDMK 1115
>26408
          Length = 463

 Score = 75.1 bits (183), Expect = 5e-14,   Method: Compositional matrix adjust.
 Identities = 33/49 (67%), Positives = 41/49 (83%)
 Frame = +1

Query: 195 QEIKESVELPLTHPEYYEEMGIKPPKGVILYGPPGTGKTLLAKAVANQT 243
           Q IKE +ELP+ HPE ++ +GI  PKGV+LYGPPGTGKTLLA+AVA+ T
Sbjct: 292 QRIKEVIELPVKHPELFDALGIAQPKGVLLYGPPGTGKTLLARAVAHHT 438

 Score = 60.1 bits (144), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 37/121 (30%), Positives = 57/121 (47%), Gaps = 4/121 (3%)
 Frame = +2

Query: 134 SILSFVDKDL----LEPGCSVLLNHKVHAVIGVLMDDTDPLVTVMKVEKAPQETYADIGG 189
           S LS +DK++    + P C V L ++ + +  +L +  DPLV++M VEK P  TY  +GG
Sbjct: 98  SSLSILDKNIDINDVTPNCRVALRNESYTLHKILPNKVDPLVSLMMVEKVPDSTYEMVGG 277

Query: 190 LDNQIQEIKESVELPLTHPEYYEEMGIKPPKGVILYGPPGTGKTLLAKAVANQTSATFLR 249
           LD QI+E +     P + P       +   +       P   K  L   +      TF+R
Sbjct: 278 LDKQIKESRR*SNCPSSIPNCSMPWALLSQRVYCCTVRPVLAKRCLPVRLPITPECTFIR 457

Query: 250 V 250
           V
Sbjct: 458 V 460
>26887
          Length = 410

 Score = 72.8 bits (177), Expect = 3e-13,   Method: Compositional matrix adjust.
 Identities = 34/38 (89%), Positives = 36/38 (94%)
 Frame = -3

Query: 294 RYDSNSGGEREIQRTMLELLNQLDGFDSRGDVKVIMAT 331
           RY+SNSGGEREIQRTMLELLNQLDGFDSRGDVKV + T
Sbjct: 168 RYESNSGGEREIQRTMLELLNQLDGFDSRGDVKVHLXT 55
>17843
          Length = 772

 Score = 57.8 bits (138), Expect = 9e-09,   Method: Compositional matrix adjust.
 Identities = 39/156 (25%), Positives = 73/156 (46%), Gaps = 15/156 (9%)
 Frame = +1

Query: 216 IKPPKGVILYGPPGTGKTLLAKAVANQ---------TSATFLRVVGSELIQKYLGDGPKL 266
           I   + ++L+GPPGTGKT L KA+A++         +    + +    L  K+  +  KL
Sbjct: 175 ISWNRVILLHGPPGTGKTTLCKALAHKLCIRLSHRFSCGQLVEINSHSLFSKWFSESGKL 354

Query: 267 VRELFRVAEEHA--PSI---VFIDEIDAIGTKRYDSNSGGE-REIQRTMLELLNQLDGFD 320
           V ++F+   ++   P +   V IDE++++   R    +G E  +  R +  +L Q+D   
Sbjct: 355 VTKMFQRLHDYMVDPELLVCVLIDEVESLTAARKSCLNGNEPSDAIRVVNAVLTQIDQLK 534

Query: 321 SRGDVKVIMATNRIETLDPALIRPGRIDRKIEFPLP 356
              +  ++  +N    +D A +    I + I  P P
Sbjct: 535 KFANCLILTTSNITGAIDLAFVDRADIKQYIGPPTP 642
>06766
          Length = 976

 Score = 44.3 bits (103), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 22/64 (34%), Positives = 37/64 (57%)
 Frame = +2

Query: 346 RIDRKIEFPLPDEKTKKRIFQIHTSRMTLADDVTLDDLIMAKDDLSGADIKAICTEAGLM 405
           R+D+ I  PLPD+K+++ I + +  +  LA +V L  +       SGAD+  IC  A  +
Sbjct: 2   RLDQLIYIPLPDDKSREAILKANLRKSPLAKEVDLTYIAKVTQGFSGADLTEICQRACKL 181

Query: 406 ALRE 409
           A+R+
Sbjct: 182 AIRQ 193
>14413
          Length = 826

 Score = 44.3 bits (103), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 38/139 (27%), Positives = 61/139 (43%), Gaps = 14/139 (10%)
 Frame = +2

Query: 232 KTLLAKAVA------NQTSATFLRVV---GSELIQKYLGDGPKLVRELFRVAEEHAPS-- 280
           KT L KA+A       Q S  +  +V      L  K+  +  KLV  LF    E A    
Sbjct: 2   KTSLCKALAEKLAIRTQNSFAYTHLVEINSHSLFSKWFSESGKLVARLFGKIGELATDKN 181

Query: 281 ---IVFIDEIDAIGTKRYDSNSGGEREIQRTMLELLNQLDGFDSRGDVKVIMATNRIETL 337
               V IDE++++   R   +S   R+  R +  +L QLD   +  +V ++  +N  +++
Sbjct: 182 NLVCVLIDEVESLAYARSAMSSNEPRDAMRVVNAVLTQLDEIKACPNVLILATSNLAQSI 361

Query: 338 DPALIRPGRIDRKIEFPLP 356
           D A +    I + I  P P
Sbjct: 362 DLAFLDRADIRQFIGLPDP 418
>01102
          Length = 1074

 Score = 39.7 bits (91), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 17/20 (85%), Positives = 19/20 (95%)
 Frame = +1

Query: 421 KSKENVLYKKQEGTPEGLYL 440
           K+KENVLY+K EGTPEGLYL
Sbjct: 64  KAKENVLYRKNEGTPEGLYL 123
>01279
          Length = 2183

 Score = 35.8 bits (81), Expect = 0.035,   Method: Compositional matrix adjust.
 Identities = 18/38 (47%), Positives = 25/38 (65%), Gaps = 2/38 (5%)
 Frame = -3

Query: 220  KGVILYGPPGTGKTLLAKAVANQ--TSATFLRVVGSEL 255
            + V+L GPPGTGKT +A A+A +      F  +VGSE+
Sbjct: 1914 RAVLLAGPPGTGKTAIALAIAQELGNKVPFCPMVGSEV 1801
>29846
          Length = 451

 Score = 35.8 bits (81), Expect = 0.036,   Method: Compositional matrix adjust.
 Identities = 18/52 (34%), Positives = 26/52 (50%)
 Frame = +1

Query: 351 IEFPLPDEKTKKRIFQIHTSRMTLADDVTLDDLIMAKDDLSGADIKAICTEA 402
           I   +P    +++IF     ++ LA D+ LD L        GADIKA+C  A
Sbjct: 142 ILISVPTSIQRRQIFNFCLRKLPLASDLDLDWLSSVTAGYVGADIKAVCASA 297
>27434
          Length = 472

 Score = 33.5 bits (75), Expect = 0.15,   Method: Compositional matrix adjust.
 Identities = 24/84 (28%), Positives = 39/84 (46%), Gaps = 11/84 (13%)
 Frame = +2

Query: 220 KGVILY--GPPGTGKTLLAKAVANQTSATFLRVVGSELI---------QKYLGDGPKLVR 268
           KG IL   GPPG GKT + +++A      F R+    +          + Y+G  P  + 
Sbjct: 158 KGPILCFVGPPGVGKTSIGRSIATTLGREFHRIALGGVCDQSDIRGHRRTYIGSMPGRII 337

Query: 269 ELFRVAEEHAPSIVFIDEIDAIGT 292
           +  + A  + P +  +DEID + T
Sbjct: 338 QGLKSAGTNNP-VFPLDEIDKLST 406
>13641
          Length = 2081

 Score = 33.5 bits (75), Expect = 0.19,   Method: Compositional matrix adjust.
 Identities = 28/82 (34%), Positives = 44/82 (53%), Gaps = 7/82 (8%)
 Frame = +2

Query: 45  AASKLPLVTPHTQCRLKLLKLERIKDYLLMEEEFIRNQEQMKPLEEKQEEER-------S 97
           AA K+ L+TPHTQ  LK L+   +K Y++    FI++     P  EK +E R       +
Sbjct: 827 AAGKVCLLTPHTQA-LKFLRTYELKPYVI----FIKS-----PTLEKLKESRMPARARAT 976

Query: 98  KVDDLRGTPMSVGTLEEIIDDN 119
           + D +R  P S+  LEE+ + +
Sbjct: 977 EADSIR--PFSIEELEEMAETS 1036
>30736
          Length = 520

 Score = 31.6 bits (70), Expect = 0.74,   Method: Compositional matrix adjust.
 Identities = 14/34 (41%), Positives = 21/34 (61%)
 Frame = -2

Query: 217 KPPKGVILYGPPGTGKTLLAKAVANQTSATFLRV 250
           +PP  + + GPP +GKT L   +AN+  A  L+V
Sbjct: 129 RPPCKLAVLGPPLSGKTTLCHLLANKYGAKVLKV 28
>37695
          Length = 156

 Score = 31.2 bits (69), Expect = 0.88,   Method: Composition-based stats.
 Identities = 13/27 (48%), Positives = 17/27 (62%)
 Frame = +3

Query: 399 CTEAGLMALRERRMKVTNEDFKKSKEN 425
           CTEAG+ A+R RR   T +DF  +  N
Sbjct: 9   CTEAGMFAIRARRKMATEKDFLDAVNN 89
>19561
          Length = 474

 Score = 30.0 bits (66), Expect = 2.1,   Method: Compositional matrix adjust.
 Identities = 24/97 (24%), Positives = 42/97 (43%), Gaps = 12/97 (12%)
 Frame = -1

Query: 220 KGVILYGPPGTGKTLLAKAVANQTSATFLRVVGSE--LIQKYLGDGPKLVRELFRVAEEH 277
           K  +L GPPG GKT LA  VA       + +  S+   ++ +        +    +  + 
Sbjct: 378 KVALLCGPPGLGKTTLAHIVAKHAGYNVVEMNASDDRSVEVFSNKIEAATQMRAVMGADP 199

Query: 278 APSIVFIDEIDAIGT----------KRYDSNSGGERE 304
            P+ + IDEID              KR ++ +GG+++
Sbjct: 198 RPNCLIIDEIDGAPQAAVNVLLNILKRPEAGAGGKKK 88
>38684
          Length = 464

 Score = 29.3 bits (64), Expect = 3.2,   Method: Compositional matrix adjust.
 Identities = 16/28 (57%), Positives = 18/28 (64%), Gaps = 1/28 (3%)
 Frame = +3

Query: 212 EEMGIKPPKGVILYGPPGTGKT-LLAKA 238
           E  G  PP   I+YGP GTGKT  LA+A
Sbjct: 327 ERTGYTPP--FIMYGPFGTGKTETLAQA 404
>02151
          Length = 1751

 Score = 28.5 bits (62), Expect = 5.3,   Method: Compositional matrix adjust.
 Identities = 22/85 (25%), Positives = 37/85 (43%), Gaps = 9/85 (10%)
 Frame = +3

Query: 143  LLEPGCSVLLNH---------KVHAVIGVLMDDTDPLVTVMKVEKAPQETYADIGGLDNQ 193
            LL P   +++NH         K  A   + ++  D L   M       ++  +IGGLDN+
Sbjct: 966  LLSPPDPIVINHVITLDGPDAKKTACYDIDVEVDDTLKQQMNSFLLSAQSQQEIGGLDNK 1145

Query: 194  IQEIKESVELPLTHPEYYEEMGIKP 218
            I E  E++    T+ E++      P
Sbjct: 1146 IHETVETINQLKTNREFFLSFARDP 1220
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6753490|ref|NP_036131.1| COP9 signalosome subunit 4
[Mus musculus]
         (406 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

32094                                                                 244   e-120
18761                                                                  28   8.2  
>32094
          Length = 820

 Score =  244 bits (624), Expect(3) = e-120,   Method: Compositional matrix adjust.
 Identities = 113/144 (78%), Positives = 128/144 (88%)
 Frame = +3

Query: 258 LAAYGILEKMYLDRIIRGNQLQEFAAMLMPHQKATTADGSSILDRAVIEHNLLSASKLYN 317
           L+ +G   KMYLDRIIR + LQEF  ML+PHQKA TADGS+I+DRAVIEHNLLSASKLYN
Sbjct: 375 LSYFG---KMYLDRIIRSSDLQEFEGMLLPHQKAITADGSTIVDRAVIEHNLLSASKLYN 545

Query: 318 NITFEELGALLEIPAAKAEKIASQMITEGRMNGFIDQIDGIVHFETREALPTWDKQIQSL 377
           NI+F ELGALLEIP AKAEKIASQMITEGRMNG++DQID IVHFE RE LP WD+QIQSL
Sbjct: 546 NISFTELGALLEIPPAKAEKIASQMITEGRMNGYVDQIDSIVHFEARETLPMWDRQIQSL 725

Query: 378 CFQVNNLLEKISQTAPEWTAQAME 401
           CFQVNN++EKISQT+P+W A+AME
Sbjct: 726 CFQVNNIIEKISQTSPDWFAKAME 797

 Score =  155 bits (391), Expect(3) = e-120,   Method: Compositional matrix adjust.
 Identities = 74/94 (78%), Positives = 83/94 (88%)
 Frame = +2

Query: 137 KQYNVDYKLETYLKIARLYLEDDDPVQAEAYINRASLLQNESTNEQLQIHYKVCYARVLD 196
           KQY+ DYKLETYLKIARLYLEDDD VQAEA+INRAS+LQ ++ NE+LQIHYK CYARVLD
Sbjct: 2   KQYSTDYKLETYLKIARLYLEDDDAVQAEAFINRASILQADTKNEELQIHYKACYARVLD 181

Query: 197 YRRKFIEAAQRYNELSYKTIVHESERLEALKHAL 230
           +RRKFIEAAQRYNELSYKTI+ E ERL  +K  L
Sbjct: 182 FRRKFIEAAQRYNELSYKTIIAEEERLNCIKKML 283

 Score = 73.2 bits (178), Expect(3) = e-120,   Method: Compositional matrix adjust.
 Identities = 35/40 (87%), Positives = 38/40 (95%)
 Frame = +1

Query: 227 KHALHCTILASAGQQRSRMLATLFKDERCQQLAAYGILEK 266
           K+AL CTILASAGQQRSRMLATLFKDERCQQL+A+ ILEK
Sbjct: 274 KNALICTILASAGQQRSRMLATLFKDERCQQLSAFHILEK 393
>18761
          Length = 492

 Score = 27.7 bits (60), Expect = 8.2,   Method: Compositional matrix adjust.
 Identities = 14/34 (41%), Positives = 18/34 (52%)
 Frame = -2

Query: 360 HFETREALPTWDKQIQSLCFQVNNLLEKISQTAP 393
           H E  E +    + ++ L  QVN LLE IS  AP
Sbjct: 266 HEEVAEEVSVCAQDVEGLAAQVNELLEAISLLAP 165
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|94407812|ref|XP_908729.2| PREDICTED: similar to
Filamin-A (Alpha-filamin) (Filamin-1) (Endothelial actin-binding
protein) (Actin-binding protein 280) (ABP-280) (Nonmuscle filamin)
isoform 10 [Mus musculus]
         (2588 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

13043                                                                 430   e-120
16231                                                                 260   1e-89
17351                                                                 253   8e-67
29446                                                                 204   4e-52
19277                                                                 178   1e-49
21436                                                                 153   1e-36
19002                                                                 102   2e-21
27230                                                                  69   6e-17
05081                                                                  75   3e-13
19147                                                                  61   6e-09
19154                                                                  59   2e-08
09100                                                                  57   8e-08
29755                                                                  56   2e-07
35059                                                                  55   5e-07
09711                                                                  54   7e-07
17613                                                                  54   7e-07
04951                                                                  42   0.004
18202                                                                  40   0.012
32088                                                                  37   0.13 
11866                                                                  32   3.0  
02928                                                                  32   3.6  
31031                                                                  32   4.5  
20490                                                                  32   4.8  
30961                                                                  31   5.6  
37715                                                                  30   8.9  
>13043
          Length = 1574

 Score =  430 bits (1106), Expect = e-120,   Method: Compositional matrix adjust.
 Identities = 237/521 (45%), Positives = 308/521 (59%), Gaps = 21/521 (4%)
 Frame = +3

Query: 1368 PSEAKMSCMDNKDGSCSVEYIPYEAGTYSLNVTYGGHQVPGSPFKVPVHDVTDASKVKCS 1427
            P EAKM C DN+DG+C VEY P + G Y ++V +G   +  SPF V + +  DASKVKC 
Sbjct: 36   PVEAKMKCDDNRDGTCRVEYYPTKPGKYDISVLFGDKPIKDSPFSVKIQNPVDASKVKCY 215

Query: 1428 GPGLSPGMVRANLPQSFQVDTSKAGVAPLQVKVQGP-KGLVEPVDVVDNADGTQTVNYVP 1486
            GPGL    V ANLP  F VD   AG APL V    P  G  +  ++V   +G     Y+P
Sbjct: 216  GPGLDASEVAANLPAVFTVDARDAGEAPLDVTFTDPLSGAQQEAEIVPVEEGLYQATYMP 395

Query: 1487 SREGSYSISVLYGEEEVPRSPFKVKVLPTHDASKVKASGPGLNTTGVPASLPVEFTIDAK 1546
              EG   + V YG + VP SPF ++VLP  D SKVK SGPG+  + VPASLP +FT+D +
Sbjct: 396  RAEGKCKVDVKYGGKPVPNSPFHMQVLPGVDPSKVKVSGPGVRRS-VPASLPAQFTVDTR 572

Query: 1547 DAGEGLLAVQITDPEGKPKKTHIQDNHDGTYTVAYVPDVPGRYTILIKYGGDEIPFSPYR 1606
            DAG   L   +  P+G   K + Q+N DGTY V Y P+  G Y I++KY G ++P SP+ 
Sbjct: 573  DAGVADLECMVQRPDGSFIKPYFQNNEDGTYDVIYTPEDLGVYDIIVKYDGQDVPRSPFN 752

Query: 1607 VRAVPTGDASKCTVTVSIXXXXXXXXXXPTIQIGEETVITVDTKAAGKGKVTCTVCTPDG 1666
            V A P GDAS+C +T               I I +ETVITVD   AGKG VTC + +P G
Sbjct: 753  VEATPLGDASQCRIT---------DGAERVIPIEKETVITVDAADAGKGSVTCRIRSPSG 905

Query: 1667 SXXXXXXXXXXXGTFDIFYTAPQPGKYVICVRFGGEHVPNSPFQV-TIPERP-------- 1717
            S           GTF I +     G+Y+I ++FGG  VP+  +    +PE          
Sbjct: 906  SDIDIDIVDQGDGTFTISFIPQYAGEYIIEIKFGGNFVPDGQYTAEAVPEDEYEKYLQSR 1085

Query: 1718 ----MVGVNGLDVTS-------LRPFDLVIPFTIKKGEITGEVRMPSGKVAQPSITDNKD 1766
                ++  + +D  +        +P D   P       ++  V MPSGK + P I DN+D
Sbjct: 1086 VVDDLIVADQVDQVNAAPGSGLYQPVDFQFPVGPIFNFVSASVIMPSGKTSYPKIEDNRD 1265

Query: 1767 GTVTVRYSPSEAGLHEMDIRYDNMHIPGSPLQFYVDYVNCGHITAYGPGLTHGVVNKPAT 1826
            GTVTVRY P+E GLHE+ ++Y+N  I GSP  F+VD VN G++TAYGPGL+HGVV +PA 
Sbjct: 1266 GTVTVRYQPTETGLHELHVKYNNECIQGSPFFFHVDSVNSGYVTAYGPGLSHGVVYEPAV 1445

Query: 1827 FTVNTKDAGEGGLSLAIEGPSKAEISCTDNQDGTCSVSYLP 1867
            FT+NTK+AG GGL+LA+EGPSK EI C DNQDGTC+VSYLP
Sbjct: 1446 FTINTKEAGAGGLALAVEGPSKTEIKCVDNQDGTCNVSYLP 1568

 Score =  271 bits (693), Expect = 2e-72,   Method: Compositional matrix adjust.
 Identities = 191/538 (35%), Positives = 273/538 (50%), Gaps = 15/538 (2%)
 Frame = +3

Query: 580  GTLGFSVEGPSQAKIECDDKGDGSCDVRYWPQEAGEYAVHVLCNSEDIRLSPFMADIREA 639
            G LG  +EGP +AK++CDD  DG+C V Y+P + G+Y + VL   + I+ SPF   I+  
Sbjct: 9    GGLGLGIEGPVEAKMKCDDNRDGTCRVEYYPTKPGKYDISVLFGDKPIKDSPFSVKIQN- 185

Query: 640  PQDFHPDRVKARGPGLEKTGVAVNKPAEFTVDAKHAGKAPLRVQVQDN-EGCSVEATVKD 698
            P D    +VK  GPGL+ + VA N PA FTVDA+ AG+APL V   D   G   EA +  
Sbjct: 186  PVDAS--KVKCYGPGLDASEVAANLPAVFTVDARDAGEAPLDVTFTDPLSGAQQEAEIVP 359

Query: 699  NGNGTYSCSYVPRKPVKHTAMVSWGGVSIPNSPFRVNVGAGSHPNKVKVYGPGVAKTGLK 758
               G Y  +Y+PR   K    V +GG  +PNSPF + V  G  P+KVKV GPGV ++ + 
Sbjct: 360  VEEGLYQATYMPRAEGKCKVDVKYGGKPVPNSPFHMQVLPGVDPSKVKVSGPGVRRS-VP 536

Query: 759  AHEPTYFTVDCTEAGQGDVSIGIKCAPGVVGPTEAXXXXXXXXXXXXTFTVKYTPCGAGS 818
            A  P  FTVD  +AG  D    ++C   V  P  +            T+ V YTP   G 
Sbjct: 537  ASLPAQFTVDTRDAGVAD----LECM--VQRPDGSFIKPYFQNNEDGTYDVIYTPEDLGV 698

Query: 819  YTIMVLFADQATPTSPIRVKVEPSHDASKVKAEGPGLNRTGVELGKPTHFTVNAKTAGKG 878
            Y I+V +  Q  P SP  V+  P  DAS+ +    G  R  + + K T  TV+A  AGKG
Sbjct: 699  YDIIVKYDGQDVPRSPFNVEATPLGDASQCRITD-GAERV-IPIEKETVITVDAADAGKG 872

Query: 879  KLDVQFSGLAKGDAVRDVDIIDHHDNTYTVKYIPVQQGPVGVNVTYGGDHIPKSPFSVGV 938
             +  +    +  D   D+DI+D  D T+T+ +IP   G   + + +GG+ +P   ++   
Sbjct: 873  SVTCRIRSPSGSDI--DIDIVDQGDGTFTISFIPQYAGEYIIEIKFGGNFVPDGQYTAEA 1046

Query: 939  SPSLDLSKIKVSGLGDKVDVGKDQEFTVKSKGAGGQ-------------GKVASKIVSPS 985
             P  +  K   S + D + V    +    + G+G                 V++ ++ PS
Sbjct: 1047 VPEDEYEKYLQSRVVDDLIVADQVDQVNAAPGSGLYQPVDFQFPVGPIFNFVSASVIMPS 1226

Query: 986  GAAVPCKVEPGLGADNSV-VRFVPREEGPYEVEVTYDGVPVPGSPFPLEAVAPTKPSKVK 1044
            G     K+E     D +V VR+ P E G +E+ V Y+   + GSPF    V       V 
Sbjct: 1227 GKTSYPKIEDN--RDGTVTVRYQPTETGLHELHVKYNNECIQGSPFFFH-VDSVNSGYVT 1397

Query: 1045 AFGPGLQGGNAGSPARFTIDTKXXXXXXXXXXVEGPCEAQLECLDNGDGTCSVSYVPT 1102
            A+GPGL  G    PA FTI+TK          VEGP + +++C+DN DGTC+VSY+P+
Sbjct: 1398 AYGPGLSHGVVYEPAVFTINTKEAGAGGLALAVEGPSKTEIKCVDNQDGTCNVSYLPS 1571

 Score =  228 bits (581), Expect = 3e-59,   Method: Compositional matrix adjust.
 Identities = 184/535 (34%), Positives = 250/535 (46%), Gaps = 26/535 (4%)
 Frame = +3

Query: 1077 VEGPCEAQLECLDNGDGTCSVSYVPTEPGDYNINILFADTHIPGSPFKAHVAPCFDASKV 1136
            +EGP EA+++C DN DGTC V Y PT+PG Y+I++LF D  I  SPF   +    DASKV
Sbjct: 27   IEGPVEAKMKCDDNRDGTCRVEYYPTKPGKYDISVLFGDKPIKDSPFSVKIQNPVDASKV 206

Query: 1137 KCSGPGLE--RATAGEVGQFQVDCSSAGSAELTIEICSE-AGLPAEVYIQDHGDGTHTIT 1193
            KC GPGL+     A     F VD   AG A L +      +G   E  I    +G +  T
Sbjct: 207  KCYGPGLDASEVAANLPAVFTVDARDAGEAPLDVTFTDPLSGAQQEAEIVPVEEGLYQAT 386

Query: 1194 YIPLCPGAYTVTIKYGGQPVPNFPSKLQVEPAVDTSGVQCYGPGIEGQGVFREATTEFSV 1253
            Y+P   G   V +KYGG+PVPN P  +QV P VD S V+  GPG+  + V      +F+V
Sbjct: 387  YMPRAEGKCKVDVKYGGKPVPNSPFHMQVLPGVDPSKVKVSGPGVR-RSVPASLPAQFTV 563

Query: 1254 DARALTQTGGPHVKARVANPSGNLTDTYVQDCGDGTYKVEYTPYEEGVHSVDVTYDGXXX 1313
            D R     G   ++  V  P G+    Y Q+  DGTY V YTP + GV+ + V YDG   
Sbjct: 564  DTR---DAGVADLECMVQRPDGSFIKPYFQNNEDGTYDVIYTPEDLGVYDIIVKYDGQDV 734

Query: 1314 XXXXXXXXXTEGCDPSRVRVHGPGIQSGTTNKPNKFTXXXXXXXXXXXXXXXXXP--SEA 1371
                     T   D S+ R+     +     K    T                 P  S+ 
Sbjct: 735  PRSPFNVEATPLGDASQCRITDGAERVIPIEKETVITVDAADAGKGSVTCRIRSPSGSDI 914

Query: 1372 KMSCMDNKDGSCSVEYIPYEAGTYSLNVTYGGHQVPGSPF---KVP------------VH 1416
             +  +D  DG+ ++ +IP  AG Y + + +GG+ VP   +    VP            V 
Sbjct: 915  DIDIVDQGDGTFTISFIPQYAGEYIIEIKFGGNFVPDGQYTAEAVPEDEYEKYLQSRVVD 1094

Query: 1417 DVTDASKVKCSGPGLSPGMVRANLPQSFQVDTSKAGVAPL----QVKVQGPKGLVEPVDV 1472
            D+  A +V         G+ +   P  FQ       V P+       V  P G      +
Sbjct: 1095 DLIVADQVDQVNAAPGSGLYQ---PVDFQFP-----VGPIFNFVSASVIMPSGKTSYPKI 1250

Query: 1473 VDNADGTQTVNYVPSREGSYSISVLYGEEEVPRSPFKVKVLPTHDASKVKASGPGLNTTG 1532
             DN DGT TV Y P+  G + + V Y  E +  SPF   V  + ++  V A GPGL + G
Sbjct: 1251 EDNRDGTVTVRYQPTETGLHELHVKYNNECIQGSPFFFHV-DSVNSGYVTAYGPGL-SHG 1424

Query: 1533 VPASLPVEFTIDAKDAGEGLLAVQITDPEGKPKKTHIQ--DNHDGTYTVAYVPDV 1585
            V    P  FTI+ K+AG G LA+ +   EG P KT I+  DN DGT  V+Y+P V
Sbjct: 1425 V-VYEPAVFTINTKEAGAGGLALAV---EG-PSKTEIKCVDNQDGTCNVSYLPSV 1574

 Score =  215 bits (547), Expect = 2e-55,   Method: Compositional matrix adjust.
 Identities = 159/513 (30%), Positives = 246/513 (47%), Gaps = 30/513 (5%)
 Frame = +3

Query: 1757 AQPSITDNKDGTVTVRYSPSEAGLHEMDIRYDNMHIPGSPLQFYV-DYVNCGHITAYGPG 1815
            A+    DN+DGT  V Y P++ G +++ + + +  I  SP    + + V+   +  YGPG
Sbjct: 45   AKMKCDDNRDGTCRVEYYPTKPGKYDISVLFGDKPIKDSPFSVKIQNPVDASKVKCYGPG 224

Query: 1816 LTHGVV--NKPATFTVNTKDAGEGGLSLAIEGP---SKAEISCTDNQDGTCSVSYLPVLP 1870
            L    V  N PA FTV+ +DAGE  L +    P   ++ E      ++G    +Y+P   
Sbjct: 225  LDASEVAANLPAVFTVDARDAGEAPLDVTFTDPLSGAQQEAEIVPVEEGLYQATYMPRAE 404

Query: 1871 GDYSILVKYNDQHIPGSPFTARVT-GDDSMRMSHLKVGSAADIP--------INISETDL 1921
            G   + VKY  + +P SPF  +V  G D  ++     G    +P        ++  +  +
Sbjct: 405  GKCKVDVKYGGKPVPNSPFHMQVLPGVDPSKVKVSGPGVRRSVPASLPAQFTVDTRDAGV 584

Query: 1922 SLLTATVVPPSGREEPCLLKRLRNGHVGISFVPKETGEHLVHVKKNGQHVASSPIPVVIS 1981
            + L   V  P G       +   +G   + + P++ G + + VK +GQ V  SP  V   
Sbjct: 585  ADLECMVQRPDGSFIKPYFQNNEDGTYDVIYTPEDLGVYDIIVKYDGQDVPRSPFNV--E 758

Query: 1982 QSEIGDASRVRVSGQGLHEGHTFEPAEFI-IDTRDAGYGGLSLSIEGPS--KVDINTEDL 2038
             + +GDAS+ R++  G       E    I +D  DAG G ++  I  PS   +DI+  D 
Sbjct: 759  ATPLGDASQCRIT-DGAERVIPIEKETVITVDAADAGKGSVTCRIRSPSGSDIDIDIVDQ 935

Query: 2039 EDGTCRVTYCPTEPGNYIINIKFADQHVPGSPFSVKVTGEGRVKESITRR---------- 2088
             DGT  +++ P   G YII IKF    VP   ++ +   E   ++ +  R          
Sbjct: 936  GDGTFTISFIPQYAGEYIIEIKFGGNFVPDGQYTAEAVPEDEYEKYLQSRVVDDLIVADQ 1115

Query: 2089 -RRAPSVANIGSHCDLSLKIPEISIQD-MTAQVTSPSGKTHEAEIVEGENHTYCIRFVPA 2146
              +  +    G +  +  + P   I + ++A V  PSGKT   +I +  + T  +R+ P 
Sbjct: 1116 VDQVNAAPGSGLYQPVDFQFPVGPIFNFVSASVIMPSGKTSYPKIEDNRDGTVTVRYQPT 1295

Query: 2147 EMGMHTVSVKYKGQHVPGSPFQFTVGPLGEGGAHKVRAGGPGLERAEAGVPAEFGIWTRE 2206
            E G+H + VKY  + + GSPF F V  +  G    V A GPGL       PA F I T+E
Sbjct: 1296 ETGLHELHVKYNNECIQGSPFFFHVDSVNSG---YVTAYGPGLSHGVVYEPAVFTINTKE 1466

Query: 2207 AGAGGLAIAVEGPSKAEISFEDRKDGSCGVAYV 2239
            AGAGGLA+AVEGPSK EI   D +DG+C V+Y+
Sbjct: 1467 AGAGGLALAVEGPSKTEIKCVDNQDGTCNVSYL 1565

 Score =  203 bits (517), Expect = 6e-52,   Method: Compositional matrix adjust.
 Identities = 163/541 (30%), Positives = 248/541 (45%), Gaps = 39/541 (7%)
 Frame = +3

Query: 1549 GEGLLAVQITDPEGKPKKTHIQDNHDGTYTVAYVPDVPGRYTILIKYGGDEIPFSPYRVR 1608
            G+G L + I  P     K    DN DGT  V Y P  PG+Y I + +G   I  SP+ V+
Sbjct: 3    GKGGLGLGIEGP--VEAKMKCDDNRDGTCRVEYYPTKPGKYDISVLFGDKPIKDSPFSVK 176

Query: 1609 AVPTGDASKCTVTVSIXXXXXXXXXXPTIQIGEETVITVDTKAAGKGKVTCTVCTP-DGS 1667
                 DASK                 P        V TVD + AG+  +  T   P  G+
Sbjct: 177  IQNPVDASKVKCYGPGLDASEVAANLPA-------VFTVDARDAGEAPLDVTFTDPLSGA 335

Query: 1668 XXXXXXXXXXXGTFDIFYTAPQPGKYVICVRFGGEHVPNSPFQVTI-----PERPMVGVN 1722
                       G +   Y     GK  + V++GG+ VPNSPF + +     P +  V V+
Sbjct: 336  QQEAEIVPVEEGLYQATYMPRAEGKCKVDVKYGGKPVPNSPFHMQVLPGVDPSK--VKVS 509

Query: 1723 GLDVTSLRPFDLVIPFTIKK-----GEITGEVRMPSGKVAQPSITDNKDGTVTVRYSPSE 1777
            G  V    P  L   FT+        ++   V+ P G   +P   +N+DGT  V Y+P +
Sbjct: 510  GPGVRRSVPASLPAQFTVDTRDAGVADLECMVQRPDGSFIKPYFQNNEDGTYDVIYTPED 689

Query: 1778 AGLHEMDIRYDNMHIPGSPLQFYVDYVNCGHITAYGPGLTHGV-----VNKPATFTVNTK 1832
             G++++ ++YD   +P SP  F V+    G  +     +T G      + K    TV+  
Sbjct: 690  LGVYDIIVKYDGQDVPRSP--FNVEATPLGDASQCR--ITDGAERVIPIEKETVITVDAA 857

Query: 1833 DAGEGGLSLAIEGPSKAEISC--TDNQDGTCSVSYLPVLPGDYSILVKYNDQHIPGSPFT 1890
            DAG+G ++  I  PS ++I     D  DGT ++S++P   G+Y I +K+    +P   +T
Sbjct: 858  DAGKGSVTCRIRSPSGSDIDIDIVDQGDGTFTISFIPQYAGEYIIEIKFGGNFVPDGQYT 1037

Query: 1891 A--------------RVTGD----DSMRMSHLKVGSAADIPINISET---DLSLLTATVV 1929
            A              RV  D    D +   +   GS    P++         + ++A+V+
Sbjct: 1038 AEAVPEDEYEKYLQSRVVDDLIVADQVDQVNAAPGSGLYQPVDFQFPVGPIFNFVSASVI 1217

Query: 1930 PPSGREEPCLLKRLRNGHVGISFVPKETGEHLVHVKKNGQHVASSPIPVVISQSEIGDAS 1989
             PSG+     ++  R+G V + + P ETG H +HVK N + +  SP    +     G   
Sbjct: 1218 MPSGKTSYPKIEDNRDGTVTVRYQPTETGLHELHVKYNNECIQGSPFFFHVDSVNSG--- 1388

Query: 1990 RVRVSGQGLHEGHTFEPAEFIIDTRDAGYGGLSLSIEGPSKVDINTEDLEDGTCRVTYCP 2049
             V   G GL  G  +EPA F I+T++AG GGL+L++EGPSK +I   D +DGTC V+Y P
Sbjct: 1389 YVTAYGPGLSHGVVYEPAVFTINTKEAGAGGLALAVEGPSKTEIKCVDNQDGTCNVSYLP 1568

Query: 2050 T 2050
            +
Sbjct: 1569 S 1571

 Score =  182 bits (461), Expect = 2e-45,   Method: Compositional matrix adjust.
 Identities = 142/516 (27%), Positives = 236/516 (45%), Gaps = 29/516 (5%)
 Frame = +3

Query: 1944 RNGHVGISFVPKETGEHLVHVKKNGQHVASSPIPVVISQSEIGDASRVRVSGQGLHEGHT 2003
            R+G   + + P + G++ + V    + +  SP  V I Q+ + DAS+V+  G GL     
Sbjct: 69   RDGTCRVEYYPTKPGKYDISVLFGDKPIKDSPFSVKI-QNPV-DASKVKCYGPGLDASEV 242

Query: 2004 FE--PAEFIIDTRDAGYGGLSLSIEGP---SKVDINTEDLEDGTCRVTYCPTEPGNYIIN 2058
                PA F +D RDAG   L ++   P   ++ +     +E+G  + TY P   G   ++
Sbjct: 243  AANLPAVFTVDARDAGEAPLDVTFTDPLSGAQQEAEIVPVEEGLYQATYMPRAEGKCKVD 422

Query: 2059 IKFADQHVPGSPFSVKV---TGEGRVKESITRRRRAPSVANIGSHCDLSLKIPEISIQDM 2115
            +K+  + VP SPF ++V       +VK S    RR+   +        ++   +  + D+
Sbjct: 423  VKYGGKPVPNSPFHMQVLPGVDPSKVKVSGPGVRRSVPAS---LPAQFTVDTRDAGVADL 593

Query: 2116 TAQVTSPSGKTHEAEIVEGENHTYCIRFVPAEMGMHTVSVKYKGQHVPGSPFQFTVGPLG 2175
               V  P G   +      E+ TY + + P ++G++ + VKY GQ VP SPF     PLG
Sbjct: 594  ECMVQRPDGSFIKPYFQNNEDGTYDVIYTPEDLGVYDIIVKYDGQDVPRSPFNVEATPLG 773

Query: 2176 EGGAHKVRAGGPGLERAEAGVPAE----FGIWTREAGAGGLAIAVEGPSKAEISFE--DR 2229
            +    ++  G      AE  +P E      +   +AG G +   +  PS ++I  +  D+
Sbjct: 774  DASQCRITDG------AERVIPIEKETVITVDAADAGKGSVTCRIRSPSGSDIDIDIVDQ 935

Query: 2230 KDGSCGVAYVVQEPGDYEVSVKFNEEHIPDSPFVVPVASPSGDARRLTVSSLQES----- 2284
             DG+  ++++ Q  G+Y + +KF    +PD  +    A P  +  +   S + +      
Sbjct: 936  GDGTFTISFIPQYAGEYIIEIKFGGNFVPDGQYTAE-AVPEDEYEKYLQSRVVDDLIVAD 1112

Query: 2285 ---------GLKVNQPASFAVSLNGAKGAIDAKVHSPSGALEECYVTEIDQDKYAVRFIP 2335
                     G  + QP  F   +      + A V  PSG      + +       VR+ P
Sbjct: 1113 QVDQVNAAPGSGLYQPVDFQFPVGPIFNFVSASVIMPSGKTSYPKIEDNRDGTVTVRYQP 1292

Query: 2336 RENGIYLIDVKFNGTHIPGSPFKIRVGEPGHGGDPGLVSAYGAGLEGGVTGSPAEFIVNT 2395
             E G++ + VK+N   I GSPF   V       + G V+AYG GL  GV   PA F +NT
Sbjct: 1293 TETGLHELHVKYNNECIQGSPFFFHV----DSVNSGYVTAYGPGLSHGVVYEPAVFTINT 1460

Query: 2396 SNAGAGALSVTIDGPSKVKMDCQECPEGY-RVTYTP 2430
              AGAG L++ ++GPSK ++ C +  +G   V+Y P
Sbjct: 1461 KEAGAGGLALAVEGPSKTEIKCVDNQDGTCNVSYLP 1568

 Score =  171 bits (433), Expect = 4e-42,   Method: Compositional matrix adjust.
 Identities = 154/541 (28%), Positives = 240/541 (44%), Gaps = 17/541 (3%)
 Frame = +3

Query: 773  GQGDVSIGIKCAPGVVGPTEAXXXXXXXXXXXXTFTVKYTPCGAGSYTIMVLFADQATPT 832
            G+G + +GI+      GP EA            T  V+Y P   G Y I VLF D+    
Sbjct: 3    GKGGLGLGIE------GPVEAKMKCDDNRDG--TCRVEYYPTKPGKYDISVLFGDKPIKD 158

Query: 833  SPIRVKVEPSHDASKVKAEGPGLNRTGVELGKPTHFTVNAKTAGKGKLDVQFSGLAKGDA 892
            SP  VK++   DASKVK  GPGL+ + V    P  FTV+A+ AG+  LDV F+    G A
Sbjct: 159  SPFSVKIQNPVDASKVKCYGPGLDASEVAANLPAVFTVDARDAGEAPLDVTFTDPLSG-A 335

Query: 893  VRDVDIIDHHDNTYTVKYIPVQQGPVGVNVTYGGDHIPKSPFSVGVSPSLDLSKIKVSGL 952
             ++ +I+   +  Y   Y+P  +G   V+V YGG  +P SPF + V P +D SK+KVSG 
Sbjct: 336  QQEAEIVPVEEGLYQATYMPRAEGKCKVDVKYGGKPVPNSPFHMQVLPGVDPSKVKVSGP 515

Query: 953  GDKVDVGKD--QEFTVKSKGAGGQGKVASKIVSPSGAAVPCKVEPGLGADNSVVRFVPRE 1010
            G +  V      +FTV ++ A G   +   +  P G+ +    +        V+ + P +
Sbjct: 516  GVRRSVPASLPAQFTVDTRDA-GVADLECMVQRPDGSFIKPYFQNNEDGTYDVI-YTPED 689

Query: 1011 EGPYEVEVTYDGVPVPGSPFPLEAVAPTKPSKVKAFGPGLQGGNAGSPARFTIDTKXXXX 1070
             G Y++ V YDG  VP SPF +EA      S+ +      +          T+D      
Sbjct: 690  LGVYDIIVKYDGQDVPRSPFNVEATPLGDASQCRITDGAERVIPIEKETVITVDAADAGK 869

Query: 1071 XXXXXXVEGP--CEAQLECLDNGDGTCSVSYVPTEPGDYNINILFADTHIPGSPFKAHVA 1128
                  +  P   +  ++ +D GDGT ++S++P   G+Y I I F    +P   + A   
Sbjct: 870  GSVTCRIRSPSGSDIDIDIVDQGDGTFTISFIPQYAGEYIIEIKFGGNFVPDGQYTAEAV 1049

Query: 1129 PCFDASKVKCSGPGLERATAGEVGQFQVDCSSAGSAELTIE-------------ICSEAG 1175
            P  +  K   S    +   A +V Q      S     +  +             +   +G
Sbjct: 1050 PEDEYEKYLQSRVVDDLIVADQVDQVNAAPGSGLYQPVDFQFPVGPIFNFVSASVIMPSG 1229

Query: 1176 LPAEVYIQDHGDGTHTITYIPLCPGAYTVTIKYGGQPVPNFPSKLQVEPAVDTSGVQCYG 1235
              +   I+D+ DGT T+ Y P   G + + +KY  + +   P    V+ +V++  V  YG
Sbjct: 1230 KTSYPKIEDNRDGTVTVRYQPTETGLHELHVKYNNECIQGSPFFFHVD-SVNSGYVTAYG 1406

Query: 1236 PGIEGQGVFREATTEFSVDARALTQTGGPHVKARVANPSGNLTDTYVQDCGDGTYKVEYT 1295
            PG+    V+  A   F+++ +   + G   +   V  PS   T+    D  DGT  V Y 
Sbjct: 1407 PGLSHGVVYEPAV--FTINTK---EAGAGGLALAVEGPSK--TEIKCVDNQDGTCNVSYL 1565

Query: 1296 P 1296
            P
Sbjct: 1566 P 1568

 Score =  160 bits (404), Expect = 9e-39,   Method: Compositional matrix adjust.
 Identities = 153/520 (29%), Positives = 237/520 (45%), Gaps = 35/520 (6%)
 Frame = +3

Query: 1835 GEGGLSLAIEGPSKAEISCTDNQDGTCSVSYLPVLPGDYSILVKYNDQHIPGSPFTARVT 1894
            G+GGL L IEGP +A++ C DN+DGTC V Y P  PG Y I V + D+ I  SPF+ ++ 
Sbjct: 3    GKGGLGLGIEGPVEAKMKCDDNRDGTCRVEYYPTKPGKYDISVLFGDKPIKDSPFSVKIQ 182

Query: 1895 GD-DSMRMSHLKVG-----SAADIP----INISETDLSLLTATVVPP-SGREEPCLLKRL 1943
               D+ ++     G      AA++P    ++  +   + L  T   P SG ++   +  +
Sbjct: 183  NPVDASKVKCYGPGLDASEVAANLPAVFTVDARDAGEAPLDVTFTDPLSGAQQEAEIVPV 362

Query: 1944 RNGHVGISFVPKETGEHLVHVKKNGQHVASSPIPVVISQSEIGDASRVRVSGQGLHEGHT 2003
              G    +++P+  G+  V VK  G+ V +SP  + +      D S+V+VSG G+     
Sbjct: 363  EEGLYQATYMPRAEGKCKVDVKYGGKPVPNSPFHMQVLPGV--DPSKVKVSGPGVRRSVP 536

Query: 2004 FE-PAEFIIDTRDAGYGGLSLSIEGP--SKVDINTEDLEDGTCRVTYCPTEPGNYIINIK 2060
               PA+F +DTRDAG   L   ++ P  S +    ++ EDGT  V Y P + G Y I +K
Sbjct: 537  ASLPAQFTVDTRDAGVADLECMVQRPDGSFIKPYFQNNEDGTYDVIYTPEDLGVYDIIVK 716

Query: 2061 FADQHVPGSPFSVKVTGEGRVKE-SITRRRRAPSVANIGSHCDLSLKIPEISIQDMTAQV 2119
            +  Q VP SPF+V+ T  G   +  IT    A  V  I     +++   +     +T ++
Sbjct: 717  YDGQDVPRSPFNVEATPLGDASQCRIT--DGAERVIPIEKETVITVDAADAGKGSVTCRI 890

Query: 2120 TSPSGKTHEAEIVEGENHTYCIRFVPAEMGMHTVSVKYKGQHVPGSPFQFTVGPLGEGGA 2179
             SPSG   + +IV+  + T+ I F+P   G + + +K+ G  VP    Q+T   + E   
Sbjct: 891  RSPSGSDIDIDIVDQGDGTFTISFIPQYAGEYIIEIKFGGNFVPDG--QYTAEAVPEDEY 1064

Query: 2180 HKV-------------------RAGGPGLERAEAGVPAEFGIWTREAGAGGLAIAVEGPS 2220
             K                     A G GL +    V  +F +           I   G +
Sbjct: 1065 EKYLQSRVVDDLIVADQVDQVNAAPGSGLYQP---VDFQFPVGPIFNFVSASVIMPSGKT 1235

Query: 2221 KAEISFEDRKDGSCGVAYVVQEPGDYEVSVKFNEEHIPDSPFVVPVASPSGDARRLTVSS 2280
                  ED +DG+  V Y   E G +E+ VK+N E I  SPF   V S   ++  +T   
Sbjct: 1236 SYP-KIEDNRDGTVTVRYQPTETGLHELHVKYNNECIQGSPFFFHVDSV--NSGYVTAYG 1406

Query: 2281 LQESGLKVNQPASFAVSLNGA-KGAIDAKVHSPSGALEEC 2319
               S   V +PA F ++   A  G +   V  PS    +C
Sbjct: 1407 PGLSHGVVYEPAVFTINTKEAGAGGLALAVEGPSKTEIKC 1526

 Score =  155 bits (393), Expect = 1e-37,   Method: Compositional matrix adjust.
 Identities = 140/516 (27%), Positives = 238/516 (46%), Gaps = 18/516 (3%)
 Frame = +3

Query: 285 GQGEVLVYVEDPAGHQEEAKVTANNDKNRTFSVWYVPEVTGTHKVTVLFAGQHIAKSPFE 344
           G+G + + +E P     EAK+  +++++ T  V Y P   G + ++VLF  + I  SPF 
Sbjct: 3   GKGGLGLGIEGPV----EAKMKCDDNRDGTCRVEYYPTKPGKYDISVLFGDKPIKDSPFS 170

Query: 345 VYVDKSQGDASKVTAQGPGLEPSGNIANKTTYFEIFTAGAGMGEVEVVIQDPTG---QKG 401
           V + ++  DASKV   GPGL+ S   AN    F +    AG   ++V   DP     Q+ 
Sbjct: 171 VKI-QNPVDASKVKCYGPGLDASEVAANLPAVFTVDARDAGEAPLDVTFTDPLSGAQQEA 347

Query: 402 TVEPQLEARGDSTYRCSYQPTMEGVHTVHVTFAGVPIPRSPYTVTVGQACNPAACRAIGR 461
            + P  E      Y+ +Y P  EG   V V + G P+P SP+ + V    +P+  +  G 
Sbjct: 348 EIVPVEEG----LYQATYMPRAEGKCKVDVKYGGKPVPNSPFHMQVLPGVDPSKVKVSGP 515

Query: 462 GLQPKGVRVKETADFKVYTKGAGSGELKVTVKGPKGEE-RVKQKDLGDGVYGFEYYPTIP 520
           G++ + V     A F V T+ AG  +L+  V+ P G   +   ++  DG Y   Y P   
Sbjct: 516 GVR-RSVPASLPAQFTVDTRDAGVADLECMVQRPDGSFIKPYFQNNEDGTYDVIYTPEDL 692

Query: 521 GTYTVTITWGGQNIGRSPFEVKVGTECGNQKVRAWGPGLEGGI-VGKSADFVVEAIGDDV 579
           G Y + + + GQ++ RSPF V+  T  G+        G E  I + K     V+A     
Sbjct: 693 GVYDIIVKYDGQDVPRSPFNVE-ATPLGDASQCRITDGAERVIPIEKETVITVDAADAGK 869

Query: 580 GTLGFSVEGPSQAKIECD--DKGDGSCDVRYWPQEAGEYAVHVLCNSEDIRLSPFMADIR 637
           G++   +  PS + I+ D  D+GDG+  + + PQ AGEY + +      +    + A+  
Sbjct: 870 GSVTCRIRSPSGSDIDIDIVDQGDGTFTISFIPQYAGEYIIEIKFGGNFVPDGQYTAE-- 1043

Query: 638 EAPQDFHPDRVKAR-------GPGLEKTGVA----VNKPAEFTVDAKHAGKAPLRVQVQD 686
             P+D +   +++R          +++   A    + +P +F           +   V  
Sbjct: 1044AVPEDEYEKYLQSRVVDDLIVADQVDQVNAAPGSGLYQPVDFQFPVGPIFNF-VSASVIM 1220

Query: 687 NEGCSVEATVKDNGNGTYSCSYVPRKPVKHTAMVSWGGVSIPNSPFRVNVGAGSHPNKVK 746
             G +    ++DN +GT +  Y P +   H   V +    I  SPF  +V +  +   V 
Sbjct: 1221PSGKTSYPKIEDNRDGTVTVRYQPTETGLHELHVKYNNECIQGSPFFFHVDS-VNSGYVT 1397

Query: 747 VYGPGVAKTGLKAHEPTYFTVDCTEAGQGDVSIGIK 782
            YGPG++   +  +EP  FT++  EAG G +++ ++
Sbjct: 1398AYGPGLSHGVV--YEPAVFTINTKEAGAGGLALAVE 1499

 Score =  150 bits (379), Expect = 7e-36,   Method: Compositional matrix adjust.
 Identities = 146/485 (30%), Positives = 219/485 (45%), Gaps = 26/485 (5%)
 Frame = +3

Query: 252 LNPKKARAYGPGIEPTGNMVKKRAEFTVETRSAGQGEVLVYVEDP-AGHQEEAKVTANND 310
           ++  K + YGPG++ +       A FTV+ R AG+  + V   DP +G Q+EA++    +
Sbjct: 189 VDASKVKCYGPGLDASEVAANLPAVFTVDARDAGEAPLDVTFTDPLSGAQQEAEIVPVEE 368

Query: 311 KNRTFSVWYVPEVTGTHKVTVLFAGQHIAKSPFEVYVDKSQGDASKVTAQGPGLEPSGNI 370
               +   Y+P   G  KV V + G+ +  SPF + V     D SKV   GPG+  S   
Sbjct: 369 G--LYQATYMPRAEGKCKVDVKYGGKPVPNSPFHMQVLPGV-DPSKVKVSGPGVRRSVP- 536

Query: 371 ANKTTYFEIFTAGAGMGEVEVVIQDPTGQKGTVEPQLEARGDSTYRCSYQPTMEGVHTVH 430
           A+    F + T  AG+ ++E ++Q P G    ++P  +   D TY   Y P   GV+ + 
Sbjct: 537 ASLPAQFTVDTRDAGVADLECMVQRPDGS--FIKPYFQNNEDGTYDVIYTPEDLGVYDII 710

Query: 431 VTFAGVPIPRSPYTVTVGQACNPAACRAIGRGLQPKGVRVKETADFKVYTKGAGSGELKV 490
           V + G  +PRSP+ V      + + CR I  G + + + +++     V    AG G +  
Sbjct: 711 VKYDGQDVPRSPFNVEATPLGDASQCR-ITDGAE-RVIPIEKETVITVDAADAGKGSVTC 884

Query: 491 TVKGPKGEE-RVKQKDLGDGVYGFEYYPTIPGTYTVTITWGGQNIGRSPFEVKVGTECGN 549
            ++ P G +  +   D GDG +   + P   G Y + I +GG  +    +  +   E   
Sbjct: 885 RIRSPSGSDIDIDIVDQGDGTFTISFIPQYAGEYIIEIKFGGNFVPDGQYTAEAVPEDEY 1064

Query: 550 QKVRAWGPGLEGGIVGKSADFVVEA--------------IGDDVGTLGFSVEGP----SQ 591
           +K       ++  IV    D V  A              +G     +  SV  P    S 
Sbjct: 1065EK-YLQSRVVDDLIVADQVDQVNAAPGSGLYQPVDFQFPVGPIFNFVSASVIMPSGKTSY 1241

Query: 592 AKIECDDKGDGSCDVRYWPQEAGEYAVHVLCNSEDIRLSPFMADIREAPQDFHPDRVK-- 649
            KIE  D  DG+  VRY P E G + +HV  N+E I+ SPF          FH D V   
Sbjct: 1242PKIE--DNRDGTVTVRYQPTETGLHELHVKYNNECIQGSPFF---------FHVDSVNSG 1388

Query: 650 ---ARGPGLEKTGVAVNKPAEFTVDAKHAGKAPLRVQVQDNEGCS-VEATVKDNGNGTYS 705
              A GPGL   GV V +PA FT++ K AG   L + V   EG S  E    DN +GT +
Sbjct: 1389YVTAYGPGLSH-GV-VYEPAVFTINTKEAGAGGLALAV---EGPSKTEIKCVDNQDGTCN 1553

Query: 706 CSYVP 710
            SY+P
Sbjct: 1554VSYLP 1568

 Score =  142 bits (359), Expect = 1e-33,   Method: Compositional matrix adjust.
 Identities = 143/530 (26%), Positives = 222/530 (41%), Gaps = 22/530 (4%)
 Frame = +3

Query: 484 GSGELKVTVKGPKGEERVKQKDLGDGVYGFEYYPTIPGTYTVTITWGGQNIGRSPFEVKV 543
           G G L + ++GP  E ++K  D  DG    EYYPT PG Y +++ +G + I  SPF VK+
Sbjct: 3   GKGGLGLGIEGPV-EAKMKCDDNRDGTCRVEYYPTKPGKYDISVLFGDKPIKDSPFSVKI 179

Query: 544 GTECGNQKVRAWGPGLEGGIVGKS--ADFVVEAIGDDVGTLGFSVEGP---SQAKIECDD 598
                  KV+ +GPGL+   V  +  A F V+A       L  +   P   +Q + E   
Sbjct: 180 QNPVDASKVKCYGPGLDASEVAANLPAVFTVDARDAGEAPLDVTFTDPLSGAQQEAEIVP 359

Query: 599 KGDGSCDVRYWPQEAGEYAVHVLCNSEDIRLSPFMADIREAPQDFHPDRVKARGPGLEKT 658
             +G     Y P+  G+  V V    + +  SPF   +        P +VK  GPG+ ++
Sbjct: 360 VEEGLYQATYMPRAEGKCKVDVKYGGKPVPNSPFHMQVLPG---VDPSKVKVSGPGVRRS 530

Query: 659 GVAVNKPAEFTVDAKHAGKAPLRVQVQDNEGCSVEATVKDNGNGTYSCSYVPRKPVKHTA 718
            V  + PA+FTVD + AG A L   VQ  +G  ++   ++N +GTY   Y P     +  
Sbjct: 531 -VPASLPAQFTVDTRDAGVADLECMVQRPDGSFIKPYFQNNEDGTYDVIYTPEDLGVYDI 707

Query: 719 MVSWGGVSIPNSPFRVNVGAGSHPNKVKVYGPGVAKTGLKAHEPTYFTVDCTEAGQGDVS 778
           +V + G  +P SPF V        ++ ++     A+  +   + T  TVD  +AG+G V+
Sbjct: 708 IVKYDGQDVPRSPFNVEATPLGDASQCRITDG--AERVIPIEKETVITVDAADAGKGSVT 881

Query: 779 IGIKCAPGVVGPTEAXXXXXXXXXXXXTFTVKYTPCGAGSYTIMVLFADQATPTSPIRVK 838
             I+       P+ +            TFT+ + P  AG Y I + F     P      +
Sbjct: 882 CRIR------SPSGSDIDIDIVDQGDGTFTISFIPQYAGEYIIEIKFGGNFVPDGQYTAE 1043

Query: 839 VEPSHDASKVKAEGPGLNRTGVELGKPTHFTVNAKTAGKG---KLDVQF----------- 884
             P  +  K        +R   +L             G G    +D QF           
Sbjct: 1044AVPEDEYEKYLQ-----SRVVDDLIVADQVDQVNAAPGSGLYQPVDFQFPVGPIFNFVSA 1208

Query: 885 SGLAKGDAVRDVDIIDHHDNTYTVKYIPVQQGPVGVNVTYGGDHIPKSPFSVGVSPSLDL 944
           S +          I D+ D T TV+Y P + G   ++V Y  + I  SPF   V     +
Sbjct: 1209SVIMPSGKTSYPKIEDNRDGTVTVRYQPTETGLHELHVKYNNECIQGSPFFFHVD---SV 1379

Query: 945 SKIKVSGLGDKVDVGKDQE---FTVKSKGAGGQGKVASKIVSPSGAAVPC 991
           +   V+  G  +  G   E   FT+ +K AG  G +A  +  PS   + C
Sbjct: 1380NSGYVTAYGPGLSHGVVYEPAVFTINTKEAGA-GGLALAVEGPSKTEIKC 1526

 Score =  136 bits (343), Expect = 1e-31,   Method: Compositional matrix adjust.
 Identities = 114/384 (29%), Positives = 178/384 (46%), Gaps = 8/384 (2%)
 Frame = +3

Query: 2208 GAGGLAIAVEGPSKAEISFEDRKDGSCGVAYVVQEPGDYEVSVKFNEEHIPDSPFVVPVA 2267
            G GGL + +EGP +A++  +D +DG+C V Y   +PG Y++SV F ++ I DSPF V + 
Sbjct: 3    GKGGLGLGIEGPVEAKMKCDDNRDGTCRVEYYPTKPGKYDISVLFGDKPIKDSPFSVKIQ 182

Query: 2268 SPSGDARRLTVS--SLQESGLKVNQPASFAVSLNGAKGA-IDAKVHSP-SGALEECYVTE 2323
            +P  DA ++      L  S +  N PA F V    A  A +D     P SGA +E  +  
Sbjct: 183  NPV-DASKVKCYGPGLDASEVAANLPAVFTVDARDAGEAPLDVTFTDPLSGAQQEAEIVP 359

Query: 2324 IDQDKYAVRFIPRENGIYLIDVKFNGTHIPGSPFKIRVGEPGHGGDPGLVSAYGAGLEGG 2383
            +++  Y   ++PR  G   +DVK+ G  +P SPF ++V     G DP  V   G G+   
Sbjct: 360  VEEGLYQATYMPRAEGKCKVDVKYGGKPVPNSPFHMQVLP---GVDPSKVKVSGPGVRRS 530

Query: 2384 VTGS-PAEFIVNTSNAGAGALSVTIDGP--SKVKMDCQECPEG-YRVTYTPMAPGSYLIS 2439
            V  S PA+F V+T +AG   L   +  P  S +K   Q   +G Y V YTP   G Y I 
Sbjct: 531  VPASLPAQFTVDTRDAGVADLECMVQRPDGSFIKPYFQNNEDGTYDVIYTPEDLGVYDII 710

Query: 2440 IKYGGPYHIGGSPFKAKVTGPRLVSNHSLHETSSVFVDSLTKVATVPQHATSGPGPADVS 2499
            +KY G   +  SPF  + T         L + S   +             T G       
Sbjct: 711  VKYDG-QDVPRSPFNVEAT--------PLGDASQCRI-------------TDG-----AE 809

Query: 2500 KVVAKGLGLSKAYVGQKSNFTVDCSKAGNNMLLVGVHGPRTPCEEILVKHMGSRLYSVSY 2559
            +V+          + +++  TVD + AG   +   +  P     +I +   G   +++S+
Sbjct: 810  RVIP---------IEKETVITVDAADAGKGSVTCRIRSPSGSDIDIDIVDQGDGTFTISF 962

Query: 2560 LLKDKGEYTLVVKWGDEHIPGSPY 2583
            + +  GEY + +K+G   +P   Y
Sbjct: 963  IPQYAGEYIIEIKFGGNFVPDGQY 1034

 Score = 99.0 bits (245), Expect = 2e-20,   Method: Compositional matrix adjust.
 Identities = 87/330 (26%), Positives = 153/330 (46%), Gaps = 16/330 (4%)
 Frame = +3

Query: 2133 EGENHTYCIRFVPAEMGMHTVSVKYKGQHVPGSPFQFTV-GPLGEGGAHKVRAGGPGLER 2191
            +  + T  + + P + G + +SV +  + +  SPF   +  P+    A KV+  GPGL+ 
Sbjct: 63   DNRDGTCRVEYYPTKPGKYDISVLFGDKPIKDSPFSVKIQNPVD---ASKVKCYGPGLDA 233

Query: 2192 AE--AGVPAEFGIWTREAGAGGLAIAVEGP---SKAEISFEDRKDGSCGVAYVVQEPGDY 2246
            +E  A +PA F +  R+AG   L +    P   ++ E      ++G     Y+ +  G  
Sbjct: 234  SEVAANLPAVFTVDARDAGEAPLDVTFTDPLSGAQQEAEIVPVEEGLYQATYMPRAEGKC 413

Query: 2247 EVSVKFNEEHIPDSPFVVPVASPSGDARRLTVSS--LQESGLKVNQPASFAVSLNGAKGA 2304
            +V VK+  + +P+SPF + V  P  D  ++ VS   ++ S +  + PA F V    A  A
Sbjct: 414  KVDVKYGGKPVPNSPFHMQVL-PGVDPSKVKVSGPGVRRS-VPASLPAQFTVDTRDAGVA 587

Query: 2305 -IDAKVHSPSGALEECYVTEIDQDKYAVRFIPRENGIYLIDVKFNGTHIPGSPFKIRVGE 2363
             ++  V  P G+  + Y    +   Y V + P + G+Y I VK++G  +P SPF +    
Sbjct: 588  DLECMVQRPDGSFIKPYFQNNEDGTYDVIYTPEDLGVYDIIVKYDGQDVPRSPFNVEATP 767

Query: 2364 PGHGGDPGLVSAYGAGLEGGVTGSPAE----FIVNTSNAGAGALSVTIDGPSKVKMDCQE 2419
             G      +        +G     P E      V+ ++AG G+++  I  PS   +D   
Sbjct: 768  LGDASQCRIT-------DGAERVIPIEKETVITVDAADAGKGSVTCRIRSPSGSDIDIDI 926

Query: 2420 CPEG---YRVTYTPMAPGSYLISIKYGGPY 2446
              +G   + +++ P   G Y+I IK+GG +
Sbjct: 927  VDQGDGTFTISFIPQYAGEYIIEIKFGGNF 1016

 Score = 75.9 bits (185), Expect = 2e-13,   Method: Compositional matrix adjust.
 Identities = 72/260 (27%), Positives = 115/260 (44%), Gaps = 11/260 (4%)
 Frame = +3

Query: 271  VKKRAEFTVETRSAGQGEVLVYVEDPAGHQEEAKVTANNDKNRTFSVWYVPEVTGTHKVT 330
            ++K    TV+   AG+G V   +  P+G   +  +    D   TF++ ++P+  G + + 
Sbjct: 822  IEKETVITVDAADAGKGSVTCRIRSPSGSDIDIDIVDQGDG--TFTISFIPQYAGEYIIE 995

Query: 331  VLFAG----------QHIAKSPFEVYVDKSQGDASKVTAQGPGLEPS-GNIANKTTYFEI 379
            + F G          + + +  +E Y+     D   V  Q   +  + G+   +   F+ 
Sbjct: 996  IKFGGNFVPDGQYTAEAVPEDEYEKYLQSRVVDDLIVADQVDQVNAAPGSGLYQPVDFQ- 1172

Query: 380  FTAGAGMGEVEVVIQDPTGQKGTVEPQLEARGDSTYRCSYQPTMEGVHTVHVTFAGVPIP 439
            F  G     V   +  P+G+  T  P++E   D T    YQPT  G+H +HV +    I 
Sbjct: 1173 FPVGPIFNFVSASVIMPSGK--TSYPKIEDNRDGTVTVRYQPTETGLHELHVKYNNECIQ 1346

Query: 440  RSPYTVTVGQACNPAACRAIGRGLQPKGVRVKETADFKVYTKGAGSGELKVTVKGPKGEE 499
             SP+   V  + N     A G GL   GV V E A F + TK AG+G L + V+GP   E
Sbjct: 1347 GSPFFFHV-DSVNSGYVTAYGPGLS-HGV-VYEPAVFTINTKEAGAGGLALAVEGPSKTE 1517

Query: 500  RVKQKDLGDGVYGFEYYPTI 519
             +K  D  DG     Y P++
Sbjct: 1518 -IKCVDNQDGTCNVSYLPSV 1574

 Score = 62.0 bits (149), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 55/193 (28%), Positives = 80/193 (41%), Gaps = 4/193 (2%)
 Frame = +3

Query: 2399 GAGALSVTIDGPSKVKMDCQECPEGY-RVTYTPMAPGSYLISIKYGGPYHIGGSPFKAKV 2457
            G G L + I+GP + KM C +  +G  RV Y P  PG Y IS+ +G    I  SPF  K+
Sbjct: 3    GKGGLGLGIEGPVEAKMKCDDNRDGTCRVEYYPTKPGKYDISVLFGDK-PIKDSPFSVKI 179

Query: 2458 TGPRLVSNHSLHETSSVFVDSLTKVATVPQHATSGPGPADVSKVVAKGLGLSKAYVGQK- 2516
              P                                    D SKV   G GL  + V    
Sbjct: 180  QNP-----------------------------------VDASKVKCYGPGLDASEVAANL 254

Query: 2517 -SNFTVDCSKAGNNMLLVGVHGPRTPCE-EILVKHMGSRLYSVSYLLKDKGEYTLVVKWG 2574
             + FTVD   AG   L V    P +  + E  +  +   LY  +Y+ + +G+  + VK+G
Sbjct: 255  PAVFTVDARDAGEAPLDVTFTDPLSGAQQEAEIVPVEEGLYQATYMPRAEGKCKVDVKYG 434

Query: 2575 DEHIPGSPYRIMV 2587
             + +P SP+ + V
Sbjct: 435  GKPVPNSPFHMQV 473
>16231
          Length = 1393

 Score =  260 bits (664), Expect(2) = 1e-89,   Method: Compositional matrix adjust.
 Identities = 143/288 (49%), Positives = 196/288 (68%), Gaps = 5/288 (1%)
 Frame = +3

Query: 286 QGEVLVYVEDPAGHQEEAKVTANNDKNRTFSVWYVPEVTGTHKVTVLFAGQHIAKSPFEV 345
           +G+V V + +P G +E  +V  NND+N T+S  YVP + G +KV +LFA + IAKSPF V
Sbjct: 177 KGDVEVSILNPKGVEETCEVEFNNDRNLTYSCAYVPTMEGHYKVNILFANKVIAKSPFTV 356

Query: 346 YVDKSQGDASKVTAQGPGLEPSGNIANKTTYFEIFTAGAGMGEVEVVIQDPTGQKGTVEP 405
            V+ + GDASKVTA GPGLE +G +A K T+FE+F  GAG G+V+VVI DP G+K  V P
Sbjct: 357 TVEGAAGDASKVTASGPGLEKTGVVATKKTFFEVFVKGAGNGKVDVVILDPHGRKDNVRP 536

Query: 406 QLEAR--GDSTYRCSYQPTMEGVHTVHVTFAGVPIPRSPYTVTVGQACNPAACRAIGRGL 463
           ++++    D+TY   Y    +G+H+V+V FAG  IP SP+ V V  A N  AC A GRG+
Sbjct: 537 KVQSAPDKDATYLVEYVTIDQGLHSVNVFFAGSQIPNSPFGVQVAPASNAKACYATGRGV 716

Query: 464 QPKGVRVKETADFKVYTKGAGSGELKVTVKGPKG-EERVKQKDLGDG--VYGFEYYPTIP 520
           QP+GVRVK+ ADF V+TKGAG GE+ V + GP G EE+ + K + D   V+   Y P+ P
Sbjct: 717 QPRGVRVKDRADFYVHTKGAGDGEVAVQIIGPGGVEEKCQLKKVPDQPEVWECVYNPSKP 896

Query: 521 GTYTVTITWGGQNIGRSPFEVKVGTECGNQKVRAWGPGLEGGIVGKSA 568
           G Y + IT+G Q+I +SPF+++VG      K+RA+GPGLEGG+V + A
Sbjct: 897 GNYIINITFGDQHISKSPFKIEVGPY-KESKIRAYGPGLEGGVVQQKA 1037

 Score = 90.5 bits (223), Expect(2) = 1e-89,   Method: Composition-based stats.
 Identities = 43/59 (72%), Positives = 48/59 (81%)
 Frame = +1

Query: 229 SVMTYLSQFPKAKLKPGAPLRPKLNPKKARAYGPGIEPTGNMVKKRAEFTVETRSAGQG 287
           S+MTYLSQFP AKLK GAPLRP+LNP + RAYGPG+EP GN V   A FTVET SAG+G
Sbjct: 7   SMMTYLSQFPNAKLKAGAPLRPRLNPARVRAYGPGLEPKGNQVGAPARFTVETFSAGRG 183

 Score =  139 bits (351), Expect(3) = 6e-60,   Method: Compositional matrix adjust.
 Identities = 106/288 (36%), Positives = 146/288 (50%), Gaps = 8/288 (2%)
 Frame = +3

Query: 774  QGDVSIGIKCAPGVVGPTEAXXXXXXXXXXXXTFTVKYTPCGAGSYTIMVLFADQATPTS 833
            +GDV + I    GV    E             T++  Y P   G Y + +LFA++    S
Sbjct: 177  KGDVEVSILNPKGV----EETCEVEFNNDRNLTYSCAYVPTMEGHYKVNILFANKVIAKS 344

Query: 834  PIRVKVE-PSHDASKVKAEGPGLNRTGVELGKPTHFTVNAKTAGKGKLDVQ-FSGLAKGD 891
            P  V VE  + DASKV A GPGL +TGV   K T F V  K AG GK+DV       + D
Sbjct: 345  PFTVTVEGAAGDASKVTASGPGLEKTGVVATKKTFFEVFVKGAGNGKVDVVILDPHGRKD 524

Query: 892  AVR-DVDIIDHHDNTYTVKYIPVQQGPVGVNVTYGGDHIPKSPFSVGVSPSLDLSKIKVS 950
             VR  V      D TY V+Y+ + QG   VNV + G  IP SPF V V+P+ +      +
Sbjct: 525  NVRPKVQSAPDKDATYLVEYVTIDQGLHSVNVFFAGSQIPNSPFGVQVAPASNAKACYAT 704

Query: 951  GLGDK---VDVGKDQEFTVKSKGAGGQGKVASKIVSPSGAAVPCKVE--PGLGADNSVVR 1005
            G G +   V V    +F V +KGA G G+VA +I+ P G    C+++  P        V 
Sbjct: 705  GRGVQPRGVRVKDRADFYVHTKGA-GDGEVAVQIIGPGGVEEKCQLKKVPDQPEVWECV- 878

Query: 1006 FVPREEGPYEVEVTYDGVPVPGSPFPLEAVAPTKPSKVKAFGPGLQGG 1053
            + P + G Y + +T+    +  SPF +E V P K SK++A+GPGL+GG
Sbjct: 879  YNPSKPGNYIINITFGDQHISKSPFKIE-VGPYKESKIRAYGPGLEGG 1019

 Score =  100 bits (249), Expect(3) = 6e-60,   Method: Compositional matrix adjust.
 Identities = 57/125 (45%), Positives = 75/125 (60%), Gaps = 4/125 (3%)
 Frame = +2

Query: 1048 PGLQGGNAGSPARFTIDTKXXXXXXXXXXVEGPCEAQLECLDNGDGTCSVSYVPTEPGDY 1107
            PG +GG A    RFT++T           +EGP +AQ+ECLDNGDG+  V Y+PT PG+Y
Sbjct: 1007 PGRRGGAA--EGRFTVETNGETGALGFS-IEGPSQAQIECLDNGDGSADVWYLPTMPGEY 1177

Query: 1108 NINILFADTHIPGSPFKAHVAPC--FDASKVKCSGPGLERA--TAGEVGQFQVDCSSAGS 1163
             ++IL +D  IP SPF A + P   FDA KV   GPGLE++     +  +F VD  +AG 
Sbjct: 1178 AVHILCSDEDIPKSPFMADIKPAADFDAEKVIAKGPGLEKSGVAPNKWAEFTVDTKAAGK 1357

Query: 1164 AELTI 1168
            A L I
Sbjct: 1358 APLVI 1372

 Score = 33.1 bits (74), Expect(3) = 6e-60,   Method: Composition-based stats.
 Identities = 14/35 (40%), Positives = 21/35 (60%)
 Frame = +1

Query: 741 HPNKVKVYGPGVAKTGLKAHEPTYFTVDCTEAGQG 775
           +P +V+ YGPG+   G +   P  FTV+   AG+G
Sbjct: 79  NPARVRAYGPGLEPKGNQVGAPARFTVETFSAGRG 183

 Score =  145 bits (365), Expect = 3e-34,   Method: Compositional matrix adjust.
 Identities = 84/154 (54%), Positives = 99/154 (64%), Gaps = 1/154 (0%)
 Frame = +2

Query: 536  RSPFEVKVGTECGNQKVRAWG-PGLEGGIVGKSADFVVEAIGDDVGTLGFSVEGPSQAKI 594
            + P + + G   G Q    W  PG  GG       F VE  G+  G LGFS+EGPSQA+I
Sbjct: 941  QKPLQDRGGPLXGEQDQGLWTRPGRRGGAA--EGRFTVETNGE-TGALGFSIEGPSQAQI 1111

Query: 595  ECDDKGDGSCDVRYWPQEAGEYAVHVLCNSEDIRLSPFMADIREAPQDFHPDRVKARGPG 654
            EC D GDGS DV Y P   GEYAVH+LC+ EDI  SPFMADI+ A  DF  ++V A+GPG
Sbjct: 1112 ECLDNGDGSADVWYLPTMPGEYAVHILCSDEDIPKSPFMADIKPA-ADFDAEKVIAKGPG 1288

Query: 655  LEKTGVAVNKPAEFTVDAKHAGKAPLRVQVQDNE 688
            LEK+GVA NK AEFTVD K AGKAPL +   D +
Sbjct: 1289 LEKSGVAPNKWAEFTVDTKAAGKAPLVITGMDTD 1390

 Score = 80.1 bits (196), Expect(3) = 6e-33,   Method: Compositional matrix adjust.
 Identities = 82/297 (27%), Positives = 121/297 (40%), Gaps = 19/297 (6%)
 Frame = +3

Query: 1550 EGLLAVQITDPEGKPKKTHIQDNHDG--TYTVAYVPDVPGRYTILIKYGGDEIPFSPYRV 1607
            +G + V I +P+G  +   ++ N+D   TY+ AYVP + G Y + I +    I  SP+ V
Sbjct: 177  KGDVEVSILNPKGVEETCEVEFNNDRNLTYSCAYVPTMEGHYKVNILFANKVIAKSPFTV 356

Query: 1608 RAV-PTGDASKCTVTVSIXXXXXXXXXXPTIQIGEETVITVDTKAAGKGKVTCTVCTPDG 1666
                  GDASK T +               +   ++T   V  K AG GKV   +  P G
Sbjct: 357  TVEGAAGDASKVTAS-------GPGLEKTGVVATKKTFFEVFVKGAGNGKVDVVILDPHG 515

Query: 1667 SXXXXXXXXXXX----GTFDIFYTAPQPGKYVICVRFGGEHVPNSPFQVTIPERPMVGV- 1721
                             T+ + Y     G + + V F G  +PNSPF V +         
Sbjct: 516  RKDNVRPKVQSAPDKDATYLVEYVTIDQGLHSVNVFFAGSQIPNSPFGVQVAPASNAKAC 695

Query: 1722 ----NGLDVTSLRPFDLVIPFTIKKGEITGEVRM----PSG---KVAQPSITDNKDGTVT 1770
                 G+    +R  D    +   KG   GEV +    P G   K     + D  +    
Sbjct: 696  YATGRGVQPRGVRVKDRADFYVHTKGAGDGEVAVQIIGPGGVEEKCQLKKVPDQPEVWEC 875

Query: 1771 VRYSPSEAGLHEMDIRYDNMHIPGSPLQFYVDYVNCGHITAYGPGLTHGVVNKPATF 1827
            V Y+PS+ G + ++I + + HI  SP +  V       I AYGPGL  GVV + A  
Sbjct: 876  V-YNPSKPGNYIINITFGDQHISKSPFKIEVGPYKESKIRAYGPGLEGGVVQQKAVL 1043

 Score = 69.7 bits (169), Expect(3) = 6e-33,   Method: Compositional matrix adjust.
 Identities = 34/68 (50%), Positives = 46/68 (67%), Gaps = 1/68 (1%)
 Frame = +2

Query: 1827 FTVNTKDAGE-GGLSLAIEGPSKAEISCTDNQDGTCSVSYLPVLPGDYSILVKYNDQHIP 1885
            FTV T   GE G L  +IEGPS+A+I C DN DG+  V YLP +PG+Y++ +  +D+ IP
Sbjct: 1040 FTVETN--GETGALGFSIEGPSQAQIECLDNGDGSADVWYLPTMPGEYAVHILCSDEDIP 1213

Query: 1886 GSPFTARV 1893
             SPF A +
Sbjct: 1214 KSPFMADI 1237

 Score = 32.3 bits (72), Expect(3) = 6e-33,   Method: Composition-based stats.
 Identities = 14/39 (35%), Positives = 21/39 (53%)
 Frame = +1

Query: 1514 PTHDASKVKASGPGLNTTGVPASLPVEFTIDAKDAGEGL 1552
            P  + ++V+A GPGL   G     P  FT++   AG G+
Sbjct: 70   PRLNPARVRAYGPGLEPKGNQVGAPARFTVETFSAGRGM 186

 Score =  106 bits (264), Expect(3) = 5e-32,   Method: Compositional matrix adjust.
 Identities = 89/283 (31%), Positives = 127/283 (44%), Gaps = 9/283 (3%)
 Frame = +3

Query: 593 KIECDDKGDGSCDVRYWPQEAGEYAVHVLCNSEDIRLSPFMADIREAPQDFHPDRVKARG 652
           ++E ++  + +    Y P   G Y V++L  ++ I  SPF   +  A  D    +V A G
Sbjct: 231 EVEFNNDRNLTYSCAYVPTMEGHYKVNILFANKVIAKSPFTVTVEGAAGD--ASKVTASG 404

Query: 653 PGLEKTGVAVNKPAEFTVDAKHAGKAPLRVQVQDNEGC--SVEATVKD--NGNGTYSCSY 708
           PGLEKTGV   K   F V  K AG   + V + D  G   +V   V+   + + TY   Y
Sbjct: 405 PGLEKTGVVATKKTFFEVFVKGAGNGKVDVVILDPHGRKDNVRPKVQSAPDKDATYLVEY 584

Query: 709 VPRKPVKHTAMVSWGGVSIPNSPFRVNVGAGSHPNKVKVYGPGVAKTGLKAHEPTYFTVD 768
           V      H+  V + G  IPNSPF V V   S+       G GV   G++  +   F V 
Sbjct: 585 VTIDQGLHSVNVFFAGSQIPNSPFGVQVAPASNAKACYATGRGVQPRGVRVKDRADFYVH 764

Query: 769 CTEAGQGDVSIGIKCAPGVVGPTEAXXXXXXXXXXXXTFTVKYTPCGAGSYTIMVLFADQ 828
              AG G+V++ I   PG V   E              +   Y P   G+Y I + F DQ
Sbjct: 765 TKGAGDGEVAVQI-IGPGGV---EEKCQLKKVPDQPEVWECVYNPSKPGNYIINITFGDQ 932

Query: 829 ATPTSPIRVKVEPSHDASKVKAEGPGL-----NRTGVELGKPT 866
               SP +++V P +  SK++A GPGL      +  V L +PT
Sbjct: 933 HISKSPFKIEVGP-YKESKIRAYGPGLEGGVVQQKAVLLWRPT 1058

 Score = 45.1 bits (105), Expect(3) = 5e-32,   Method: Compositional matrix adjust.
 Identities = 27/82 (32%), Positives = 39/82 (47%), Gaps = 5/82 (6%)
 Frame = +2

Query: 896  VDIIDHHDNTYTVKYIPVQQGPVGVNVTYGGDHIPKSPFSVGVSPSLDLSKIKVSGLG-- 953
            ++ +D+ D +  V Y+P   G   V++    + IPKSPF   + P+ D    KV   G  
Sbjct: 1109 IECLDNGDGSADVWYLPTMPGEYAVHILCSDEDIPKSPFMADIKPAADFDAEKVIAKGPG 1288

Query: 954  ---DKVDVGKDQEFTVKSKGAG 972
                 V   K  EFTV +K AG
Sbjct: 1289 LEKSGVAPNKWAEFTVDTKAAG 1354

 Score = 27.7 bits (60), Expect(3) = 5e-32,   Method: Composition-based stats.
 Identities = 15/25 (60%), Positives = 17/25 (68%), Gaps = 2/25 (8%)
 Frame = +1

Query: 551 KVRAWGPGLE--GGIVGKSADFVVE 573
           +VRA+GPGLE  G  VG  A F VE
Sbjct: 88  RVRAYGPGLEPKGNQVGAPARFTVE 162

 Score =  105 bits (263), Expect(2) = 2e-31,   Method: Compositional matrix adjust.
 Identities = 74/211 (35%), Positives = 104/211 (49%), Gaps = 2/211 (0%)
 Frame = +3

Query: 256 KARAYGPGIEPTGNMVKKRAEFTVETRSAGQGEVLVYVEDPAGHQEEA--KVTANNDKNR 313
           K  A GPG+E TG +  K+  F V  + AG G+V V + DP G ++    KV +  DK+ 
Sbjct: 387 KVTASGPGLEKTGVVATKKTFFEVFVKGAGNGKVDVVILDPHGRKDNVRPKVQSAPDKDA 566

Query: 314 TFSVWYVPEVTGTHKVTVLFAGQHIAKSPFEVYVDKSQGDASKVTAQGPGLEPSGNIANK 373
           T+ V YV    G H V V FAG  I  SPF V V  +  +A    A G G++P G     
Sbjct: 567 TYLVEYVTIDQGLHSVNVFFAGSQIPNSPFGVQVAPAS-NAKACYATGRGVQPRGVRVKD 743

Query: 374 TTYFEIFTAGAGMGEVEVVIQDPTGQKGTVEPQLEARGDSTYRCSYQPTMEGVHTVHVTF 433
              F + T GAG GEV V I  P G +   + +        + C Y P+  G + +++TF
Sbjct: 744 RADFYVHTKGAGDGEVAVQIIGPGGVEEKCQLKKVPDQPEVWECVYNPSKPGNYIINITF 923

Query: 434 AGVPIPRSPYTVTVGQACNPAACRAIGRGLQ 464
               I +SP+ + VG     +  RA G GL+
Sbjct: 924 GDQHISKSPFKIEVG-PYKESKIRAYGPGLE 1013

 Score = 50.8 bits (120), Expect(2) = 2e-31,   Method: Compositional matrix adjust.
 Identities = 38/102 (37%), Positives = 56/102 (54%), Gaps = 4/102 (3%)
 Frame = +2

Query: 476  FKVYTKGAGSGELKVTVKGPKGEERVKQKDLGDGVYGFEYYPTIPGTYTVTITWGGQNIG 535
            F V T G  +G L  +++GP  + +++  D GDG     Y PT+PG Y V I    ++I 
Sbjct: 1040 FTVETNGE-TGALGFSIEGPS-QAQIECLDNGDGSADVWYLPTMPGEYAVHILCSDEDIP 1213

Query: 536  RSPF--EVKVGTECGNQKVRAWGPGLEGGIVG--KSADFVVE 573
            +SPF  ++K   +   +KV A GPGLE   V   K A+F V+
Sbjct: 1214 KSPFMADIKPAADFDAEKVIAKGPGLEKSGVAPNKWAEFTVD 1339

 Score =  111 bits (278), Expect(2) = 2e-29,   Method: Compositional matrix adjust.
 Identities = 85/267 (31%), Positives = 121/267 (45%), Gaps = 1/267 (0%)
 Frame = +3

Query: 688 EGCSVEATVKDNGNGTYSCSYVPRKPVKHTAMVSWGGVSIPNSPFRVNV-GAGSHPNKVK 746
           E C VE    ++ N TYSC+YVP     +   + +    I  SPF V V GA    +KV 
Sbjct: 222 ETCEVE--FNNDRNLTYSCAYVPTMEGHYKVNILFANKVIAKSPFTVTVEGAAGDASKVT 395

Query: 747 VYGPGVAKTGLKAHEPTYFTVDCTEAGQGDVSIGIKCAPGVVGPTEAXXXXXXXXXXXXT 806
             GPG+ KTG+ A + T+F V    AG G V + I    G                   T
Sbjct: 396 ASGPGLEKTGVVATKKTFFEVFVKGAGNGKVDVVILDPHG--RKDNVRPKVQSAPDKDAT 569

Query: 807 FTVKYTPCGAGSYTIMVLFADQATPTSPIRVKVEPSHDASKVKAEGPGLNRTGVELGKPT 866
           + V+Y     G +++ V FA    P SP  V+V P+ +A    A G G+   GV +    
Sbjct: 570 YLVEYVTIDQGLHSVNVFFAGSQIPNSPFGVQVAPASNAKACYATGRGVQPRGVRVKDRA 749

Query: 867 HFTVNAKTAGKGKLDVQFSGLAKGDAVRDVDIIDHHDNTYTVKYIPVQQGPVGVNVTYGG 926
            F V+ K AG G++ VQ  G    +    +  +      +   Y P + G   +N+T+G 
Sbjct: 750 DFYVHTKGAGDGEVAVQIIGPGGVEEKCQLKKVPDQPEVWECVYNPSKPGNYIINITFGD 929

Query: 927 DHIPKSPFSVGVSPSLDLSKIKVSGLG 953
            HI KSPF + V P  + SKI+  G G
Sbjct: 930 QHISKSPFKIEVGPYKE-SKIRAYGPG 1007

 Score = 38.5 bits (88), Expect(2) = 2e-29,   Method: Composition-based stats.
 Identities = 19/39 (48%), Positives = 23/39 (58%)
 Frame = +1

Query: 643 FHPDRVKARGPGLEKTGVAVNKPAEFTVDAKHAGKAPLR 681
            +P RV+A GPGLE  G  V  PA FTV+   AG+   R
Sbjct: 76  LNPARVRAYGPGLEPKGNQVGAPARFTVETFSAGRGMWR 192

 Score = 89.0 bits (219), Expect(2) = 1e-28,   Method: Compositional matrix adjust.
 Identities = 72/280 (25%), Positives = 125/280 (44%), Gaps = 13/280 (4%)
 Frame = +3

Query: 1924 LTATVVPPSGREEPCLLK--RLRNGHVGISFVPKETGEHLVHVKKNGQHVASSPIPVVIS 1981
            +  +++ P G EE C ++    RN     ++VP   G + V++    + +A SP  V + 
Sbjct: 186  VEVSILNPKGVEETCEVEFNNDRNLTYSCAYVPTMEGHYKVNILFANKVIAKSPFTVTV- 362

Query: 1982 QSEIGDASRVRVSGQGLHEGHTFEPAE--FIIDTRDAGYGGLSLSIEGPS------KVDI 2033
            +   GDAS+V  SG GL +       +  F +  + AG G + + I  P       +  +
Sbjct: 363  EGAAGDASKVTASGPGLEKTGVVATKKTFFEVFVKGAGNGKVDVVILDPHGRKDNVRPKV 542

Query: 2034 NTEDLEDGTCRVTYCPTEPGNYIINIKFADQHVPGSPFSVKVTGEGRVKESI-TRRRRAP 2092
             +   +D T  V Y   + G + +N+ FA   +P SPF V+V      K    T R   P
Sbjct: 543  QSAPDKDATYLVEYVTIDQGLHSVNVFFAGSQIPNSPFGVQVAPASNAKACYATGRGVQP 722

Query: 2093 SVANIGSHCDLSLKIPEISIQDMTAQVTSPSGKTHEAEI--VEGENHTYCIRFVPAEMGM 2150
                +    D  +        ++  Q+  P G   + ++  V  +   +   + P++ G 
Sbjct: 723  RGVRVKDRADFYVHTKGAGDGEVAVQIIGPGGVEEKCQLKKVPDQPEVWECVYNPSKPGN 902

Query: 2151 HTVSVKYKGQHVPGSPFQFTVGPLGEGGAHKVRAGGPGLE 2190
            + +++ +  QH+  SPF+  VGP  E    K+RA GPGLE
Sbjct: 903  YIINITFGDQHISKSPFKIEVGPYKES---KIRAYGPGLE 1013

 Score = 58.5 bits (140), Expect(2) = 1e-28,   Method: Compositional matrix adjust.
 Identities = 39/120 (32%), Positives = 58/120 (48%), Gaps = 19/120 (15%)
 Frame = +2

Query: 2201 GIWTREAGAGG----------------LAIAVEGPSKAEISFEDRKDGSCGVAYVVQEPG 2244
            G+WTR    GG                L  ++EGPS+A+I   D  DGS  V Y+   PG
Sbjct: 992  GLWTRPGRRGGAAEGRFTVETNGETGALGFSIEGPSQAQIECLDNGDGSADVWYLPTMPG 1171

Query: 2245 DYEVSVKFNEEHIPDSPFVVPVA-SPSGDARRLTVS--SLQESGLKVNQPASFAVSLNGA 2301
            +Y V +  ++E IP SPF+  +  +   DA ++      L++SG+  N+ A F V    A
Sbjct: 1172 EYAVHILCSDEDIPKSPFMADIKPAADFDAEKVIAKGPGLEKSGVAPNKWAEFTVDTKAA 1351

 Score = 97.8 bits (242), Expect(3) = 7e-28,   Method: Compositional matrix adjust.
 Identities = 79/277 (28%), Positives = 122/277 (44%), Gaps = 14/277 (5%)
 Frame = +3

Query: 1266 VKARVANPSGNLTDTYVQDCGDG--TYKVEYTPYEEGVHSVDVTYDGXXXXXXXXXXXXT 1323
            V+  + NP G      V+   D   TY   Y P  EG + V++ +               
Sbjct: 186  VEVSILNPKGVEETCEVEFNNDRNLTYSCAYVPTMEGHYKVNILF-ANKVIAKSPFTVTV 362

Query: 1324 EGC--DPSRVRVHGPGIQSG--TTNKPNKFTXXXXXXXXXXXXXXXXXPS------EAKM 1373
            EG   D S+V   GPG++       K   F                  P         K+
Sbjct: 363  EGAAGDASKVTASGPGLEKTGVVATKKTFFEVFVKGAGNGKVDVVILDPHGRKDNVRPKV 542

Query: 1374 SCMDNKDGSCSVEYIPYEAGTYSLNVTYGGHQVPGSPFKVPVHDVTDASKVKCSGPGLSP 1433
                +KD +  VEY+  + G +S+NV + G Q+P SPF V V   ++A     +G G+ P
Sbjct: 543  QSAPDKDATYLVEYVTIDQGLHSVNVFFAGSQIPNSPFGVQVAPASNAKACYATGRGVQP 722

Query: 1434 GMVRANLPQSFQVDTSKAGVAPLQVKVQGPKGLVEPVDVVDNADGTQTVN--YVPSREGS 1491
              VR      F V T  AG   + V++ GP G+ E   +    D  +     Y PS+ G+
Sbjct: 723  RGVRVKDRADFYVHTKGAGDGEVAVQIIGPGGVEEKCQLKKVPDQPEVWECVYNPSKPGN 902

Query: 1492 YSISVLYGEEEVPRSPFKVKVLPTHDASKVKASGPGL 1528
            Y I++ +G++ + +SPFK++V P +  SK++A GPGL
Sbjct: 903  YIINITFGDQHISKSPFKIEVGP-YKESKIRAYGPGL 1010

 Score = 42.0 bits (97), Expect(3) = 7e-28,   Method: Compositional matrix adjust.
 Identities = 30/99 (30%), Positives = 42/99 (42%), Gaps = 2/99 (2%)
 Frame = +2

Query: 1564 PKKTHIQ--DNHDGTYTVAYVPDVPGRYTILIKYGGDEIPFSPYRVRAVPTGDASKCTVT 1621
            P +  I+  DN DG+  V Y+P +PG Y + I    ++IP SP+     P  D     V 
Sbjct: 1094 PSQAQIECLDNGDGSADVWYLPTMPGEYAVHILCSDEDIPKSPFMADIKPAADFDAEKVI 1273

Query: 1622 VSIXXXXXXXXXXPTIQIGEETVITVDTKAAGKGKVTCT 1660
                           +   +    TVDTKAAGK  +  T
Sbjct: 1274 AK-----GPGLEKSGVAPNKWAEFTVDTKAAGKAPLVIT 1375

 Score = 25.0 bits (53), Expect(3) = 7e-28,   Method: Composition-based stats.
 Identities = 11/33 (33%), Positives = 20/33 (60%)
 Frame = +1

Query: 1222 VEPAVDTSGVQCYGPGIEGQGVFREATTEFSVD 1254
            + P ++ + V+ YGPG+E +G    A   F+V+
Sbjct: 64   LRPRLNPARVRAYGPGLEPKGNQVGAPARFTVE 162

 Score =  115 bits (288), Expect(2) = 2e-26,   Method: Compositional matrix adjust.
 Identities = 79/242 (32%), Positives = 116/242 (47%), Gaps = 7/242 (2%)
 Frame = +3

Query: 1377 DNKDGSCSVEYIPYEAGTYSLNVTYGGHQVPGSPFKVPVHDVT-DASKVKCSGPGLSPGM 1435
            ++++ + S  Y+P   G Y +N+ +    +  SPF V V     DASKV  SGPGL    
Sbjct: 246  NDRNLTYSCAYVPTMEGHYKVNILFANKVIAKSPFTVTVEGAAGDASKVTASGPGLEKTG 425

Query: 1436 VRANLPQSFQVDTSKAGVAPLQVKVQGPKGL---VEP-VDVVDNADGTQTVNYVPSREGS 1491
            V A     F+V    AG   + V +  P G    V P V    + D T  V YV   +G 
Sbjct: 426  VVATKKTFFEVFVKGAGNGKVDVVILDPHGRKDNVRPKVQSAPDKDATYLVEYVTIDQGL 605

Query: 1492 YSISVLYGEEEVPRSPFKVKVLPTHDASKVKASGPGLNTTGVPASLPVEFTIDAKDAGEG 1551
            +S++V +   ++P SPF V+V P  +A    A+G G+   GV      +F +  K AG+G
Sbjct: 606  HSVNVFFAGSQIPNSPFGVQVAPASNAKACYATGRGVQPRGVRVKDRADFYVHTKGAGDG 785

Query: 1552 LLAVQITDPEGKPKKTHIQDNHDG--TYTVAYVPDVPGRYTILIKYGGDEIPFSPYRVRA 1609
             +AVQI  P G  +K  ++   D    +   Y P  PG Y I I +G   I  SP+++  
Sbjct: 786  EVAVQIIGPGGVEEKCQLKKVPDQPEVWECVYNPSKPGNYIINITFGDQHISKSPFKIEV 965

Query: 1610 VP 1611
             P
Sbjct: 966  GP 971

 Score = 24.6 bits (52), Expect(2) = 2e-26,   Method: Composition-based stats.
 Identities = 10/26 (38%), Positives = 16/26 (61%), Gaps = 2/26 (7%)
 Frame = +1

Query: 1327 DPSRVRVHGPGIQ--SGTTNKPNKFT 1350
            +P+RVR +GPG++        P +FT
Sbjct: 79   NPARVRAYGPGLEPKGNQVGAPARFT 156

 Score = 84.0 bits (206), Expect(2) = 1e-24,   Method: Compositional matrix adjust.
 Identities = 52/140 (37%), Positives = 74/140 (52%), Gaps = 2/140 (1%)
 Frame = +3

Query: 228 HSVMTYL--SQFPKAKLKPGAPLRPKLNPKKARAYGPGIEPTGNMVKKRAEFTVETRSAG 285
           HSV  +   SQ P +    G  + P  N K   A G G++P G  VK RA+F V T+ AG
Sbjct: 606 HSVNVFFAGSQIPNSPF--GVQVAPASNAKACYATGRGVQPRGVRVKDRADFYVHTKGAG 779

Query: 286 QGEVLVYVEDPAGHQEEAKVTANNDKNRTFSVWYVPEVTGTHKVTVLFAGQHIAKSPFEV 345
            GEV V +  P G +E+ ++    D+   +   Y P   G + + + F  QHI+KSPF++
Sbjct: 780 DGEVAVQIIGPGGVEEKCQLKKVPDQPEVWECVYNPSKPGNYIINITFGDQHISKSPFKI 959

Query: 346 YVDKSQGDASKVTAQGPGLE 365
            V   +   SK+ A GPGLE
Sbjct: 960 EVGPYK--ESKIRAYGPGLE 1013

 Score = 50.1 bits (118), Expect(2) = 1e-24,   Method: Compositional matrix adjust.
 Identities = 39/118 (33%), Positives = 55/118 (46%), Gaps = 9/118 (7%)
 Frame = +2

Query: 383  GAGMGEVEVVIQDPTGQ-----KGTVEPQLEA--RGDSTYRCSYQPTMEGVHTVHVTFAG 435
            GA  G   V     TG      +G  + Q+E    GD +    Y PTM G + VH+  + 
Sbjct: 1022 GAAEGRFTVETNGETGALGFSIEGPSQAQIECLDNGDGSADVWYLPTMPGEYAVHILCSD 1201

Query: 436  VPIPRSPYTVTVGQACNPAACRAI--GRGLQPKGVRVKETADFKVYTKGAGSGELKVT 491
              IP+SP+   +  A +  A + I  G GL+  GV   + A+F V TK AG   L +T
Sbjct: 1202 EDIPKSPFMADIKPAADFDAEKVIAKGPGLEKSGVAPNKWAEFTVDTKAAGKAPLVIT 1375

 Score =  112 bits (281), Expect = 2e-24,   Method: Compositional matrix adjust.
 Identities = 95/296 (32%), Positives = 143/296 (48%), Gaps = 17/296 (5%)
 Frame = +3

Query: 2114 DMTAQVTSPSG--KTHEAEIVEGENHTYCIRFVPAEMGMHTVSVKYKGQHVPGSPFQFTV 2171
            D+   + +P G  +T E E     N TY   +VP   G + V++ +  + +  SPF  TV
Sbjct: 183  DVEVSILNPKGVEETCEVEFNNDRNLTYSCAYVPTMEGHYKVNILFANKVIAKSPFTVTV 362

Query: 2172 GPLGEGGAHKVRAGGPGLERAEAGVPAE----FGIWTREAGAGGLAIAVEGPS------K 2221
                 G A KV A GPGLE+   GV A     F ++ + AG G + + +  P       +
Sbjct: 363  -EGAAGDASKVTASGPGLEKT--GVVATKKTFFEVFVKGAGNGKVDVVILDPHGRKDNVR 533

Query: 2222 AEISFEDRKDGSCGVAYVVQEPGDYEVSVKFNEEHIPDSPFVVPVASPSGDARRL--TVS 2279
             ++     KD +  V YV  + G + V+V F    IP+SPF V VA P+ +A+    T  
Sbjct: 534  PKVQSAPDKDATYLVEYVTIDQGLHSVNVFFAGSQIPNSPFGVQVA-PASNAKACYATGR 710

Query: 2280 SLQESGLKVNQPASFAVSLNGA-KGAIDAKVHSPSGALEECYVTEI-DQ-DKYAVRFIPR 2336
             +Q  G++V   A F V   GA  G +  ++  P G  E+C + ++ DQ + +   + P 
Sbjct: 711  GVQPRGVRVKDRADFYVHTKGAGDGEVAVQIIGPGGVEEKCQLKKVPDQPEVWECVYNPS 890

Query: 2337 ENGIYLIDVKFNGTHIPGSPFKIRVGEPGHGGDPGLVSAYGAGLEGGVTGSPAEFI 2392
            + G Y+I++ F   HI  SPFKI VG          + AYG GLEGGV    A  +
Sbjct: 891  KPGNYIINITFGDQHISKSPFKIEVGPYKESK----IRAYGPGLEGGVVQQKAVLL 1046

 Score =  112 bits (280), Expect = 2e-24,   Method: Compositional matrix adjust.
 Identities = 78/247 (31%), Positives = 124/247 (50%), Gaps = 12/247 (4%)
 Frame = +3

Query: 2223 EISFEDRKDGSCGVAYVVQEPGDYEVSVKFNEEHIPDSPFVVPVASPSGDARRLTVS--S 2280
            E+ F + ++ +   AYV    G Y+V++ F  + I  SPF V V   +GDA ++T S   
Sbjct: 231  EVEFNNDRNLTYSCAYVPTMEGHYKVNILFANKVIAKSPFTVTVEGAAGDASKVTASGPG 410

Query: 2281 LQESGLKVNQPASFAVSLNGA-KGAIDAKVHSPSGALEEC---YVTEIDQDK-YAVRFIP 2335
            L+++G+   +   F V + GA  G +D  +  P G  +       +  D+D  Y V ++ 
Sbjct: 411  LEKTGVVATKKTFFEVFVKGAGNGKVDVVILDPHGRKDNVRPKVQSAPDKDATYLVEYVT 590

Query: 2336 RENGIYLIDVKFNGTHIPGSPFKIRVGEPGHGGDPGLVSAYGAGLEGGVTGSPAEFIVNT 2395
             + G++ ++V F G+ IP SPF ++V  P         +  G    G      A+F V+T
Sbjct: 591  IDQGLHSVNVFFAGSQIPNSPFGVQVA-PASNAKACYATGRGVQPRGVRVKDRADFYVHT 767

Query: 2396 SNAGAGALSVTIDGPSKVKMDCQ-----ECPEGYRVTYTPMAPGSYLISIKYGGPYHIGG 2450
              AG G ++V I GP  V+  CQ     + PE +   Y P  PG+Y+I+I +G   HI  
Sbjct: 768  KGAGDGEVAVQIIGPGGVEEKCQLKKVPDQPEVWECVYNPSKPGNYIINITFGD-QHISK 944

Query: 2451 SPFKAKV 2457
            SPFK +V
Sbjct: 945  SPFKIEV 965

 Score = 81.3 bits (199), Expect(2) = 8e-21,   Method: Compositional matrix adjust.
 Identities = 70/277 (25%), Positives = 127/277 (45%), Gaps = 25/277 (9%)
 Frame = +3

Query: 1836 EGGLSLAIEGPSKAEISC----TDNQDGTCSVSYLPVLPGDYSILVKYNDQHIPGSPFTA 1891
            +G + ++I  P   E +C     ++++ T S +Y+P + G Y + + + ++ I  SPFT 
Sbjct: 177  KGDVEVSILNPKGVEETCEVEFNNDRNLTYSCAYVPTMEGHYKVNILFANKVIAKSPFTV 356

Query: 1892 RVTG--DDSMRMSHLKVGSAADIPINISETDLSLLT---------ATVVPPSGREEPCLL 1940
             V G   D+ +++    G      +   +T   +             ++ P GR++    
Sbjct: 357  TVEGAAGDASKVTASGPGLEKTGVVATKKTFFEVFVKGAGNGKVDVVILDPHGRKDNVRP 536

Query: 1941 KRL----RNGHVGISFVPKETGEHLVHVKKNGQHVASSPIPVVISQSEIGDASRVRVSGQ 1996
            K      ++    + +V  + G H V+V   G  + +SP  V ++ +   +A     +G+
Sbjct: 537  KVQSAPDKDATYLVEYVTIDQGLHSVNVFFAGSQIPNSPFGVQVAPAS--NAKACYATGR 710

Query: 1997 GLHEG--HTFEPAEFIIDTRDAGYGGLSLSIEGP----SKVDINTEDLEDGTCRVTYCPT 2050
            G+        + A+F + T+ AG G +++ I GP     K  +     +       Y P+
Sbjct: 711  GVQPRGVRVKDRADFYVHTKGAGDGEVAVQIIGPGGVEEKCQLKKVPDQPEVWECVYNPS 890

Query: 2051 EPGNYIINIKFADQHVPGSPFSVKVTGEGRVKESITR 2087
            +PGNYIINI F DQH+  SPF ++V   G  KES  R
Sbjct: 891  KPGNYIINITFGDQHISKSPFKIEV---GPYKESKIR 992

 Score = 39.7 bits (91), Expect(2) = 8e-21,   Method: Compositional matrix adjust.
 Identities = 28/91 (30%), Positives = 46/91 (50%), Gaps = 4/91 (4%)
 Frame = +2

Query: 2128 EAEIVEGENHTYCIRFVPAEMGMHTVSVKYKGQHVPGSPFQFTVGPLGEGGAHKVRAGGP 2187
            + E ++  + +  + ++P   G + V +    + +P SPF   + P  +  A KV A GP
Sbjct: 1106 QIECLDNGDGSADVWYLPTMPGEYAVHILCSDEDIPKSPFMADIKPAADFDAEKVIAKGP 1285

Query: 2188 GLERAEAGVP----AEFGIWTREAGAGGLAI 2214
            GLE+  +GV     AEF + T+ AG   L I
Sbjct: 1286 GLEK--SGVAPNKWAEFTVDTKAAGKAPLVI 1372

 Score = 97.1 bits (240), Expect = 9e-20,   Method: Compositional matrix adjust.
 Identities = 83/299 (27%), Positives = 132/299 (44%), Gaps = 16/299 (5%)
 Frame = +3

Query: 974  QGKVASKIVSPSGAAVPCKVEPGLGADNSVVR---FVPREEGPYEVEVTYDGVPVPGSPF 1030
            +G V   I++P G    C+VE     D ++     +VP  EG Y+V + +    +  SPF
Sbjct: 177  KGDVEVSILNPKGVEETCEVE--FNNDRNLTYSCAYVPTMEGHYKVNILFANKVIAKSPF 350

Query: 1031 PLEAV-APTKPSKVKAFGPGLQ--GGNAGSPARFTIDTKXXXXXXXXXXVEGP------C 1081
             +    A    SKV A GPGL+  G  A     F +  K          +  P       
Sbjct: 351  TVTVEGAAGDASKVTASGPGLEKTGVVATKKTFFEVFVKGAGNGKVDVVILDPHGRKDNV 530

Query: 1082 EAQLECLDNGDGTCSVSYVPTEPGDYNINILFADTHIPGSPFKAHVAPCFDASKVKCSGP 1141
              +++   + D T  V YV  + G +++N+ FA + IP SPF   VAP  +A     +G 
Sbjct: 531  RPKVQSAPDKDATYLVEYVTIDQGLHSVNVFFAGSQIPNSPFGVQVAPASNAKACYATGR 710

Query: 1142 GLE--RATAGEVGQFQVDCSSAGSAELTIEICSEAGLPAEVYIQDHGDG--THTITYIPL 1197
            G++       +   F V    AG  E+ ++I    G+  +  ++   D        Y P 
Sbjct: 711  GVQPRGVRVKDRADFYVHTKGAGDGEVAVQIIGPGGVEEKCQLKKVPDQPEVWECVYNPS 890

Query: 1198 CPGAYTVTIKYGGQPVPNFPSKLQVEPAVDTSGVQCYGPGIEGQGVFREATTEFSVDAR 1256
             PG Y + I +G Q +   P K++V P  + S ++ YGPG+EG  V ++A   +   AR
Sbjct: 891  KPGNYIINITFGDQHISKSPFKIEVGPYKE-SKIRAYGPGLEGGVVQQKAVLLWRPTAR 1064

 Score = 70.9 bits (172), Expect(3) = 1e-17,   Method: Compositional matrix adjust.
 Identities = 69/240 (28%), Positives = 101/240 (42%), Gaps = 26/240 (10%)
 Frame = +3

Query: 1680 TFDIFYTAPQPGKYVICVRFGGEHVPNSPFQVTI-----------PERPMVGVNGLDVTS 1728
            T+   Y     G Y + + F  + +  SPF VT+              P +   G+  T 
Sbjct: 261  TYSCAYVPTMEGHYKVNILFANKVIAKSPFTVTVEGAAGDASKVTASGPGLEKTGVVATK 440

Query: 1729 LRPFDLVIPFTIKKGEITGEVRM----PSGKV--AQPSITD--NKDGTVTVRYSPSEAGL 1780
               F++ +     KG   G+V +    P G+    +P +    +KD T  V Y   + GL
Sbjct: 441  KTFFEVFV-----KGAGNGKVDVVILDPHGRKDNVRPKVQSAPDKDATYLVEYVTIDQGL 605

Query: 1781 HEMDIRYDNMHIPGSPLQFYVD-YVNCGHITAYGPGLT-HGV-VNKPATFTVNTKDAGEG 1837
            H +++ +    IP SP    V    N     A G G+   GV V   A F V+TK AG+G
Sbjct: 606  HSVNVFFAGSQIPNSPFGVQVAPASNAKACYATGRGVQPRGVRVKDRADFYVHTKGAGDG 785

Query: 1838 GLSLAIEGPSKAEISC----TDNQDGTCSVSYLPVLPGDYSILVKYNDQHIPGSPFTARV 1893
             +++ I GP   E  C      +Q       Y P  PG+Y I + + DQHI  SPF   V
Sbjct: 786  EVAVQIIGPGGVEEKCQLKKVPDQPEVWECVYNPSKPGNYIINITFGDQHISKSPFKIEV 965

 Score = 37.4 bits (85), Expect(3) = 1e-17,   Method: Compositional matrix adjust.
 Identities = 28/103 (27%), Positives = 48/103 (46%), Gaps = 2/103 (1%)
 Frame = +2

Query: 1924 LTATVVPPSGREEPCLLKRLRNGHVGISFVPKETGEHLVHVKKNGQHVASSPIPVVISQS 1983
            L  ++  PS  +  CL     +G   + ++P   GE+ VH+  + + +  SP    I  +
Sbjct: 1073 LGFSIEGPSQAQIECLDNG--DGSADVWYLPTMPGEYAVHILCSDEDIPKSPFMADIKPA 1246

Query: 1984 EIGDASRVRVSGQGLHEGHTF--EPAEFIIDTRDAGYGGLSLS 2024
               DA +V   G GL +      + AEF +DT+ AG   L ++
Sbjct: 1247 ADFDAEKVIAKGPGLEKSGVAPNKWAEFTVDTKAAGKAPLVIT 1375

 Score = 21.9 bits (45), Expect(3) = 1e-17,   Method: Composition-based stats.
 Identities = 11/30 (36%), Positives = 15/30 (50%)
 Frame = +1

Query: 1638 QIGEETVITVDTKAAGKGKVTCTVCTPDGS 1667
            Q+G     TV+T +AG+G   C   T   S
Sbjct: 130  QVGAPARFTVETFSAGRGMWRCLFSTLKAS 219

 Score = 79.0 bits (193), Expect = 3e-14,   Method: Compositional matrix adjust.
 Identities = 72/268 (26%), Positives = 122/268 (45%), Gaps = 20/268 (7%)
 Frame = +3

Query: 2019 GGLSLSIEGPSKVDINTE----DLEDGTCRVTYCPTEPGNYIINIKFADQHVPGSPFSVK 2074
            G + +SI  P  V+   E    +  + T    Y PT  G+Y +NI FA++ +  SPF+V 
Sbjct: 180  GDVEVSILNPKGVEETCEVEFNNDRNLTYSCAYVPTMEGHYKVNILFANKVIAKSPFTVT 359

Query: 2075 VTGEG----RVKESITRRRRAPSVANIGSHCDLSLKIPEISIQDMTAQVTSPSGKTH--- 2127
            V G      +V  S     +   VA   +  ++ +K       D+   +  P G+     
Sbjct: 360  VEGAAGDASKVTASGPGLEKTGVVATKKTFFEVFVKGAGNGKVDVV--ILDPHGRKDNVR 533

Query: 2128 -EAEIVEGENHTYCIRFVPAEMGMHTVSVKYKGQHVPGSPFQFTVGPLGEGGAHKVRAGG 2186
             + +    ++ TY + +V  + G+H+V+V + G  +P SPF   V P     A    A G
Sbjct: 534  PKVQSAPDKDATYLVEYVTIDQGLHSVNVFFAGSQIPNSPFGVQVAPASN--AKACYATG 707

Query: 2187 PGLERAEAGVP--AEFGIWTREAGAGGLAIAVEGPSKAEISFEDRK------DGSCGVAY 2238
             G++     V   A+F + T+ AG G +A+ + GP   E   + +K         C   Y
Sbjct: 708  RGVQPRGVRVKDRADFYVHTKGAGDGEVAVQIIGPGGVEEKCQLKKVPDQPEVWEC--VY 881

Query: 2239 VVQEPGDYEVSVKFNEEHIPDSPFVVPV 2266
               +PG+Y +++ F ++HI  SPF + V
Sbjct: 882  NPSKPGNYIINITFGDQHISKSPFKIEV 965

 Score = 73.6 bits (179), Expect = 9e-13,   Method: Compositional matrix adjust.
 Identities = 42/118 (35%), Positives = 65/118 (55%), Gaps = 2/118 (1%)
 Frame = +2

Query: 1444 FQVDTSKAGVAPLQVKVQGPKGLVEPVDVVDNADGTQTVNYVPSREGSYSISVLYGEEEV 1503
            F V+T+      L   ++GP      ++ +DN DG+  V Y+P+  G Y++ +L  +E++
Sbjct: 1040 FTVETNGE-TGALGFSIEGPS--QAQIECLDNGDGSADVWYLPTMPGEYAVHILCSDEDI 1210

Query: 1504 PRSPFKVKVLPT--HDASKVKASGPGLNTTGVPASLPVEFTIDAKDAGEGLLAVQITD 1559
            P+SPF   + P    DA KV A GPGL  +GV  +   EFT+D K AG+  L +   D
Sbjct: 1211 PKSPFMADIKPAADFDAEKVIAKGPGLEKSGVAPNKWAEFTVDTKAAGKAPLVITGMD 1384

 Score = 68.9 bits (167), Expect = 3e-11,   Method: Compositional matrix adjust.
 Identities = 37/93 (39%), Positives = 49/93 (52%), Gaps = 2/93 (2%)
 Frame = +2

Query: 1368 PSEAKMSCMDNKDGSCSVEYIPYEAGTYSLNVTYGGHQVPGSPFKVPVHDVT--DASKVK 1425
            PS+A++ C+DN DGS  V Y+P   G Y++++      +P SPF   +      DA KV 
Sbjct: 1094 PSQAQIECLDNGDGSADVWYLPTMPGEYAVHILCSDEDIPKSPFMADIKPAADFDAEKVI 1273

Query: 1426 CSGPGLSPGMVRANLPQSFQVDTSKAGVAPLQV 1458
              GPGL    V  N    F VDT  AG APL +
Sbjct: 1274 AKGPGLEKSGVAPNKWAEFTVDTKAAGKAPLVI 1372

 Score = 67.4 bits (163), Expect = 6e-11,   Method: Compositional matrix adjust.
 Identities = 76/300 (25%), Positives = 120/300 (40%), Gaps = 14/300 (4%)
 Frame = +3

Query: 2302 KGAIDAKVHSPSGALEECYVTEIDQDK---YAVRFIPRENGIYLIDVKFNGTHIPGSPFK 2358
            KG ++  + +P G  E C V E + D+   Y+  ++P   G Y +++ F    I  SPF 
Sbjct: 177  KGDVEVSILNPKGVEETCEV-EFNNDRNLTYSCAYVPTMEGHYKVNILFANKVIAKSPFT 353

Query: 2359 IRVGEPGHGGDPGLVSAYGAGLE--GGVTGSPAEFIVNTSNAGAGALSVTIDGP----SK 2412
            + V   G  GD   V+A G GLE  G V      F V    AG G + V I  P      
Sbjct: 354  VTV--EGAAGDASKVTASGPGLEKTGVVATKKTFFEVFVKGAGNGKVDVVILDPHGRKDN 527

Query: 2413 VKMDCQECPEG---YRVTYTPMAPGSYLISIKYGGPYHIGGSPFKAKVTGPRLVSNHSLH 2469
            V+   Q  P+    Y V Y  +  G + +++ + G   I  SPF  +V      SN    
Sbjct: 528  VRPKVQSAPDKDATYLVEYVTIDQGLHSVNVFFAGS-QIPNSPFGVQVAP---ASN---- 683

Query: 2470 ETSSVFVDSLTKVATVPQHATSGPGPADVSKVVAKGLGLSKAYVGQKSNFTVDCSKAGNN 2529
                                      A       +G+      V  +++F V    AG+ 
Sbjct: 684  --------------------------AKACYATGRGVQPRGVRVKDRADFYVHTKGAGDG 785

Query: 2530 MLLVGVHGPRTPCEEILVKHMGSR--LYSVSYLLKDKGEYTLVVKWGDEHIPGSPYRIMV 2587
             + V + GP    E+  +K +  +  ++   Y     G Y + + +GD+HI  SP++I V
Sbjct: 786  EVAVQIIGPGGVEEKCQLKKVPDQPEVWECVYNPSKPGNYIINITFGDQHISKSPFKIEV 965

 Score = 59.3 bits (142), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 40/120 (33%), Positives = 62/120 (51%), Gaps = 1/120 (0%)
 Frame = +2

Query: 277  FTVETRSAGQGEVLVYVEDPAGHQEEAKVTANNDKNRTFSVWYVPEVTGTHKVTVLFAGQ 336
            FTVET     G +   +E P+    +A++   ++ + +  VWY+P + G + V +L + +
Sbjct: 1040 FTVETNGE-TGALGFSIEGPS----QAQIECLDNGDGSADVWYLPTMPGEYAVHILCSDE 1204

Query: 337  HIAKSPFEVYVD-KSQGDASKVTAQGPGLEPSGNIANKTTYFEIFTAGAGMGEVEVVIQD 395
             I KSPF   +   +  DA KV A+GPGLE SG   NK   F + T  AG   + +   D
Sbjct: 1205 DIPKSPFMADIKPAADFDAEKVIAKGPGLEKSGVAPNKWAEFTVDTKAAGKAPLVITGMD 1384

 Score = 58.2 bits (139), Expect = 5e-08,   Method: Compositional matrix adjust.
 Identities = 31/74 (41%), Positives = 42/74 (56%), Gaps = 2/74 (2%)
 Frame = +2

Query: 809  VKYTPCGAGSYTIMVLFADQATPTSPIRVKVEPS--HDASKVKAEGPGLNRTGVELGKPT 866
            V Y P   G Y + +L +D+  P SP    ++P+   DA KV A+GPGL ++GV   K  
Sbjct: 1145 VWYLPTMPGEYAVHILCSDEDIPKSPFMADIKPAADFDAEKVIAKGPGLEKSGVAPNKWA 1324

Query: 867  HFTVNAKTAGKGKL 880
             FTV+ K AGK  L
Sbjct: 1325 EFTVDTKAAGKAPL 1366

 Score = 55.1 bits (131), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 39/116 (33%), Positives = 58/116 (50%), Gaps = 3/116 (2%)
 Frame = +2

Query: 1145 RATAGEVGQFQVDCS-SAGSAELTIEICSEAGLPAEVYIQDHGDGTHTITYIPLCPGAYT 1203
            R  A E G+F V+ +   G+   +IE  S+A    ++   D+GDG+  + Y+P  PG Y 
Sbjct: 1016 RGGAAE-GRFTVETNGETGALGFSIEGPSQA----QIECLDNGDGSADVWYLPTMPGEYA 1180

Query: 1204 VTIKYGGQPVPNFPSKLQVEPAVDTSG--VQCYGPGIEGQGVFREATTEFSVDARA 1257
            V I    + +P  P    ++PA D     V   GPG+E  GV      EF+VD +A
Sbjct: 1181 VHILCSDEDIPKSPFMADIKPAADFDAEKVIAKGPGLEKSGVAPNKWAEFTVDTKA 1348

 Score = 53.9 bits (128), Expect = 7e-07,   Method: Compositional matrix adjust.
 Identities = 25/57 (43%), Positives = 33/57 (57%)
 Frame = +2

Query: 2019 GGLSLSIEGPSKVDINTEDLEDGTCRVTYCPTEPGNYIINIKFADQHVPGSPFSVKV 2075
            G L  SIEGPS+  I   D  DG+  V Y PT PG Y ++I  +D+ +P SPF   +
Sbjct: 1067 GALGFSIEGPSQAQIECLDNGDGSADVWYLPTMPGEYAVHILCSDEDIPKSPFMADI 1237

 Score = 47.0 bits (110), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 36/125 (28%), Positives = 56/125 (44%), Gaps = 13/125 (10%)
 Frame = +2

Query: 668  FTVDAKHAGKAPLRVQVQDNE-----GCSVEATVK------DNGNGTYSCSYVPRKPVKH 716
            +T   +  G A  R  V+ N      G S+E   +      DNG+G+    Y+P  P ++
Sbjct: 998  WTRPGRRGGAAEGRFTVETNGETGALGFSIEGPSQAQIECLDNGDGSADVWYLPTMPGEY 1177

Query: 717  TAMVSWGGVSIPNSPFRVNV--GAGSHPNKVKVYGPGVAKTGLKAHEPTYFTVDCTEAGQ 774
               +      IP SPF  ++   A     KV   GPG+ K+G+  ++   FTVD   AG+
Sbjct: 1178 AVHILCSDEDIPKSPFMADIKPAADFDAEKVIAKGPGLEKSGVAPNKWAEFTVDTKAAGK 1357

Query: 775  GDVSI 779
              + I
Sbjct: 1358 APLVI 1372

 Score = 43.9 bits (102), Expect = 8e-04,   Method: Compositional matrix adjust.
 Identities = 46/156 (29%), Positives = 66/156 (42%), Gaps = 5/156 (3%)
 Frame = +2

Query: 2383 GVTGSPAE--FIVNTSNAGAGALSVTIDGPSKVKMDCQECPEG-YRVTYTPMAPGSYLIS 2439
            G  G  AE  F V T N   GAL  +I+GPS+ +++C +  +G   V Y P  PG Y + 
Sbjct: 1010 GRRGGAAEGRFTVET-NGETGALGFSIEGPSQAQIECLDNGDGSADVWYLPTMPGEYAVH 1186

Query: 2440 IKYGGPYHIGGSPFKAKVTGPRLVSNHSLHETSSVFVDSLTKVATVPQHATSGPGPADVS 2499
            I                     L S+  + +  S F+  +   A             D  
Sbjct: 1187 I---------------------LCSDEDIPK--SPFMADIKPAADF-----------DAE 1264

Query: 2500 KVVAKGLGLSKAYVG--QKSNFTVDCSKAGNNMLLV 2533
            KV+AKG GL K+ V   + + FTVD   AG   L++
Sbjct: 1265 KVIAKGPGLEKSGVAPNKWAEFTVDTKAAGKAPLVI 1372

 Score = 40.4 bits (93), Expect = 0.010,   Method: Composition-based stats.
 Identities = 21/55 (38%), Positives = 32/55 (58%)
 Frame = +1

Query: 833 SPIRVKVEPSHDASKVKAEGPGLNRTGVELGKPTHFTVNAKTAGKGKLDVQFSGL 887
           +P+R ++ P+    +V+A GPGL   G ++G P  FTV   +AG+G     FS L
Sbjct: 58  APLRPRLNPA----RVRAYGPGLEPKGNQVGAPARFTVETFSAGRGMWRCLFSTL 210

 Score = 38.9 bits (89), Expect = 0.027,   Method: Composition-based stats.
 Identities = 22/47 (46%), Positives = 32/47 (68%), Gaps = 9/47 (19%)
 Frame = +1

Query: 1028 SPFP---LEAVAPTKP----SKVKAFGPGLQ--GGNAGSPARFTIDT 1065
            S FP   L+A AP +P    ++V+A+GPGL+  G   G+PARFT++T
Sbjct: 25   SQFPNAKLKAGAPLRPRLNPARVRAYGPGLEPKGNQVGAPARFTVET 165

 Score = 37.0 bits (84), Expect = 0.095,   Method: Compositional matrix adjust.
 Identities = 20/52 (38%), Positives = 32/52 (61%)
 Frame = +2

Query: 240  AKLKPGAPLRPKLNPKKARAYGPGIEPTGNMVKKRAEFTVETRSAGQGEVLV 291
            A +KP A      + +K  A GPG+E +G    K AEFTV+T++AG+  +++
Sbjct: 1229 ADIKPAA----DFDAEKVIAKGPGLEKSGVAPNKWAEFTVDTKAAGKAPLVI 1372

 Score = 35.4 bits (80), Expect = 0.33,   Method: Composition-based stats.
 Identities = 19/35 (54%), Positives = 21/35 (60%)
 Frame = +1

Query: 452 NPAACRAIGRGLQPKGVRVKETADFKVYTKGAGSG 486
           NPA  RA G GL+PKG +V   A F V T  AG G
Sbjct: 79  NPARVRAYGPGLEPKGNQVGAPARFTVETFSAGRG 183

 Score = 32.7 bits (73), Expect = 2.1,   Method: Composition-based stats.
 Identities = 17/36 (47%), Positives = 21/36 (58%), Gaps = 2/36 (5%)
 Frame = +1

Query: 353 DASKVTAQGPGLEPSGNIANKTTYF--EIFTAGAGM 386
           + ++V A GPGLEP GN       F  E F+AG GM
Sbjct: 79  NPARVRAYGPGLEPKGNQVGAPARFTVETFSAGRGM 186

 Score = 32.0 bits (71), Expect = 3.4,   Method: Compositional matrix adjust.
 Identities = 12/35 (34%), Positives = 19/35 (54%)
 Frame = +2

Query: 1679 GTFDIFYTAPQPGKYVICVRFGGEHVPNSPFQVTI 1713
            G+ D++Y    PG+Y + +    E +P SPF   I
Sbjct: 1133 GSADVWYLPTMPGEYAVHILCSDEDIPKSPFMADI 1237
>17351
          Length = 654

 Score =  253 bits (646), Expect = 8e-67,   Method: Compositional matrix adjust.
 Identities = 121/216 (56%), Positives = 156/216 (72%)
 Frame = -1

Query: 2110 ISIQDMTAQVTSPSGKTHEAEIVEGENHTYCIRFVPAEMGMHTVSVKYKGQHVPGSPFQF 2169
            I+  D+ A VTSPS  T +AEI E E+  Y + FVP E+G+HTVSV+Y   H+PGSPFQF
Sbjct: 654  ITSFDLAACVTSPSNVTEDAEIQEIEDGLYSVHFVPKELGVHTVSVRYSEMHIPGSPFQF 475

Query: 2170 TVGPLGEGGAHKVRAGGPGLERAEAGVPAEFGIWTREAGAGGLAIAVEGPSKAEISFEDR 2229
            TVGPL + G+H V+AGG GLER   G PAEF +WTREAG G LAI+VEGPSKA+I F+DR
Sbjct: 474  TVGPLRDSGSHLVKAGGSGLERGVVGEPAEFNVWTREAGGGSLAISVEGPSKADIEFKDR 295

Query: 2230 KDGSCGVAYVVQEPGDYEVSVKFNEEHIPDSPFVVPVASPSGDARRLTVSSLQESGLKVN 2289
            KDGSC V+Y V EPG+Y V +KFN+ HIPDSPF V ++  +GDA +L V    +  ++ +
Sbjct: 294  KDGSCDVSYKVTEPGEYRVGLKFNDRHIPDSPFKVYISPDAGDAHKLEVQQFPQGNIQAD 115

Query: 2290 QPASFAVSLNGAKGAIDAKVHSPSGALEECYVTEID 2325
             P  F V  NGAKG +DAK+ +PSG  ++C++  ID
Sbjct: 114  APYQFMVRKNGAKGELDAKIVAPSGTDDDCFIQAID 7

 Score =  136 bits (342), Expect = 1e-31,   Method: Compositional matrix adjust.
 Identities = 78/215 (36%), Positives = 115/215 (53%), Gaps = 11/215 (5%)
 Frame = -1

Query: 1740 IKKGEITGEVRMPSGKVAQPSITDNKDGTVTVRYSPSEAGLHEMDIRYDNMHIPGSPLQF 1799
            I   ++   V  PS       I + +DG  +V + P E G+H + +RY  MHIPGSP QF
Sbjct: 654  ITSFDLAACVTSPSNVTEDAEIQEIEDGLYSVHFVPKELGVHTVSVRYSEMHIPGSPFQF 475

Query: 1800 YVDYVN---CGHITAYGPGLTHGVVNKPATFTVNTKDAGEGGLSLAIEGPSKAEISCTDN 1856
             V  +       + A G GL  GVV +PA F V T++AG G L++++EGPSKA+I   D 
Sbjct: 474  TVGPLRDSGSHLVKAGGSGLERGVVGEPAEFNVWTREAGGGSLAISVEGPSKADIEFKDR 295

Query: 1857 QDGTCSVSYLPVLPGDYSILVKYNDQHIPGSPFTARVTGD----DSMRMSHLKVGS-AAD 1911
            +DG+C VSY    PG+Y + +K+ND+HIP SPF   ++ D      + +     G+  AD
Sbjct: 294  KDGSCDVSYKVTEPGEYRVGLKFNDRHIPDSPFKVYISPDAGDAHKLEVQQFPQGNIQAD 115

Query: 1912 IPINI---SETDLSLLTATVVPPSGREEPCLLKRL 1943
             P             L A +V PSG ++ C ++ +
Sbjct: 114  APYQFMVRKNGAKGELDAKIVAPSGTDDDCFIQAI 10

 Score =  124 bits (310), Expect = 6e-28,   Method: Compositional matrix adjust.
 Identities = 63/153 (41%), Positives = 89/153 (58%)
 Frame = -1

Query: 1924 LTATVVPPSGREEPCLLKRLRNGHVGISFVPKETGEHLVHVKKNGQHVASSPIPVVISQS 1983
            L A V  PS   E   ++ + +G   + FVPKE G H V V+ +  H+  SP    +   
Sbjct: 639  LAACVTSPSNVTEDAEIQEIEDGLYSVHFVPKELGVHTVSVRYSEMHIPGSPFQFTVGPL 460

Query: 1984 EIGDASRVRVSGQGLHEGHTFEPAEFIIDTRDAGYGGLSLSIEGPSKVDINTEDLEDGTC 2043
                +  V+  G GL  G   EPAEF + TR+AG G L++S+EGPSK DI  +D +DG+C
Sbjct: 459  RDSGSHLVKAGGSGLERGVVGEPAEFNVWTREAGGGSLAISVEGPSKADIEFKDRKDGSC 280

Query: 2044 RVTYCPTEPGNYIINIKFADQHVPGSPFSVKVT 2076
             V+Y  TEPG Y + +KF D+H+P SPF V ++
Sbjct: 279  DVSYKVTEPGEYRVGLKFNDRHIPDSPFKVYIS 181

 Score =  111 bits (278), Expect = 4e-24,   Method: Compositional matrix adjust.
 Identities = 62/153 (40%), Positives = 93/153 (60%), Gaps = 1/153 (0%)
 Frame = -1

Query: 2307 AKVHSPSGALEECYVTEIDQDKYAVRFIPRENGIYLIDVKFNGTHIPGSPFKIRVGEPGH 2366
            A V SPS   E+  + EI+   Y+V F+P+E G++ + V+++  HIPGSPF+  VG P  
Sbjct: 633  ACVTSPSNVTEDAEIQEIEDGLYSVHFVPKELGVHTVSVRYSEMHIPGSPFQFTVG-PLR 457

Query: 2367 GGDPGLVSAYGAGLEGGVTGSPAEFIVNTSNAGAGALSVTIDGPSKVKMDCQECPEGY-R 2425
                 LV A G+GLE GV G PAEF V T  AG G+L+++++GPSK  ++ ++  +G   
Sbjct: 456  DSGSHLVKAGGSGLERGVVGEPAEFNVWTREAGGGSLAISVEGPSKADIEFKDRKDGSCD 277

Query: 2426 VTYTPMAPGSYLISIKYGGPYHIGGSPFKAKVT 2458
            V+Y    PG Y + +K+    HI  SPFK  ++
Sbjct: 276  VSYKVTEPGEYRVGLKFND-RHIPDSPFKVYIS 181

 Score =  108 bits (271), Expect = 2e-23,   Method: Compositional matrix adjust.
 Identities = 79/214 (36%), Positives = 110/214 (51%), Gaps = 7/214 (3%)
 Frame = -1

Query: 977  VASKIVSPSGA---AVPCKVEPGLGADNSVVRFVPREEGPYEVEVTYDGVPVPGSPFPLE 1033
            +A+ + SPS     A   ++E GL +    V FVP+E G + V V Y  + +PGSPF   
Sbjct: 639  LAACVTSPSNVTEDAEIQEIEDGLYS----VHFVPKELGVHTVSVRYSEMHIPGSPFQF- 475

Query: 1034 AVAPTKPSK---VKAFGPGLQGGNAGSPARFTIDTKXXXXXXXXXXVEGPCEAQLECLDN 1090
             V P + S    VKA G GL+ G  G PA F + T+          VEGP +A +E  D 
Sbjct: 474  TVGPLRDSGSHLVKAGGSGLERGVVGEPAEFNVWTREAGGGSLAISVEGPSKADIEFKDR 295

Query: 1091 GDGTCSVSYVPTEPGDYNINILFADTHIPGSPFKAHVAP-CFDASKVKCSGPGLERATAG 1149
             DG+C VSY  TEPG+Y + + F D HIP SPFK +++P   DA K++          A 
Sbjct: 294  KDGSCDVSYKVTEPGEYRVGLKFNDRHIPDSPFKVYISPDAGDAHKLEVQQFPQGNIQAD 115

Query: 1150 EVGQFQVDCSSAGSAELTIEICSEAGLPAEVYIQ 1183
               QF V  + A   EL  +I + +G   + +IQ
Sbjct: 114  APYQFMVRKNGA-KGELDAKIVAPSGTDDDCFIQ 16

 Score = 97.1 bits (240), Expect = 8e-20,   Method: Compositional matrix adjust.
 Identities = 70/203 (34%), Positives = 101/203 (49%), Gaps = 3/203 (1%)
 Frame = -1

Query: 485 SGELKVTVKGPKG-EERVKQKDLGDGVYGFEYYPTIPGTYTVTITWGGQNIGRSPFEVKV 543
           S +L   V  P    E  + +++ DG+Y   + P   G +TV++ +   +I  SPF+  V
Sbjct: 648 SFDLAACVTSPSNVTEDAEIQEIEDGLYSVHFVPKELGVHTVSVRYSEMHIPGSPFQFTV 469

Query: 544 G--TECGNQKVRAWGPGLEGGIVGKSADFVVEAIGDDVGTLGFSVEGPSQAKIECDDKGD 601
           G   + G+  V+A G GLE G+VG+ A+F V       G+L  SVEGPS+A IE  D+ D
Sbjct: 468 GPLRDSGSHLVKAGGSGLERGVVGEPAEFNVWTREAGGGSLAISVEGPSKADIEFKDRKD 289

Query: 602 GSCDVRYWPQEAGEYAVHVLCNSEDIRLSPFMADIREAPQDFHPDRVKARGPGLEKTGVA 661
           GSCDV Y   E GEY V +  N   I  SPF   I     D H   V+       +  + 
Sbjct: 288 GSCDVSYKVTEPGEYRVGLKFNDRHIPDSPFKVYISPDAGDAHKLEVQQ----FPQGNIQ 121

Query: 662 VNKPAEFTVDAKHAGKAPLRVQV 684
            + P +F V  K+  K  L  ++
Sbjct: 120 ADAPYQFMV-RKNGAKGELDAKI 55

 Score = 85.1 bits (209), Expect = 4e-16,   Method: Compositional matrix adjust.
 Identities = 57/168 (33%), Positives = 83/168 (49%), Gaps = 3/168 (1%)
 Frame = -1

Query: 1456 LQVKVQGPKGLVEPVDVVDNADGTQTVNYVPSREGSYSISVLYGEEEVPRSPFKVKVLPT 1515
            L   V  P  + E  ++ +  DG  +V++VP   G +++SV Y E  +P SPF+  V P 
Sbjct: 639  LAACVTSPSNVTEDAEIQEIEDGLYSVHFVPKELGVHTVSVRYSEMHIPGSPFQFTVGPL 460

Query: 1516 HDASK--VKASGPGLNTTGVPASLPVEFTIDAKDAGEGLLAVQITDPEGKPKKTHIQDNH 1573
             D+    VKA G GL    V    P EF +  ++AG G LA+ +  P         +D  
Sbjct: 459  RDSGSHLVKAGGSGLERGVV--GEPAEFNVWTREAGGGSLAISVEGP--SKADIEFKDRK 292

Query: 1574 DGTYTVAYVPDVPGRYTILIKYGGDEIPFSPYRVRAVP-TGDASKCTV 1620
            DG+  V+Y    PG Y + +K+    IP SP++V   P  GDA K  V
Sbjct: 291  DGSCDVSYKVTEPGEYRVGLKFNDRHIPDSPFKVYISPDAGDAHKLEV 148

 Score = 82.0 bits (201), Expect = 3e-15,   Method: Compositional matrix adjust.
 Identities = 59/191 (30%), Positives = 95/191 (49%), Gaps = 3/191 (1%)
 Frame = -1

Query: 807 FTVKYTPCGAGSYTIMVLFADQATPTSPIRVKVEPSHDASK--VKAEGPGLNRTGVELGK 864
           ++V + P   G +T+ V +++   P SP +  V P  D+    VKA G GL R GV +G+
Sbjct: 567 YSVHFVPKELGVHTVSVRYSEMHIPGSPFQFTVGPLRDSGSHLVKAGGSGLER-GV-VGE 394

Query: 865 PTHFTVNAKTAGKGKLDVQFSGLAKGDAVRDVDIIDHHDNTYTVKYIPVQQGPVGVNVTY 924
           P  F V  + AG G L +   G +K D    ++  D  D +  V Y   + G   V + +
Sbjct: 393 PAEFNVWTREAGGGSLAISVEGPSKAD----IEFKDRKDGSCDVSYKVTEPGEYRVGLKF 226

Query: 925 GGDHIPKSPFSVGVSPSL-DLSKIKVSGLGDKVDVGKDQEFTVKSKGAGGQGKVASKIVS 983
              HIP SPF V +SP   D  K++V     + ++  D  +    +  G +G++ +KIV+
Sbjct: 225 NDRHIPDSPFKVYISPDAGDAHKLEVQQF-PQGNIQADAPYQFMVRKNGAKGELDAKIVA 49

Query: 984 PSGAAVPCKVE 994
           PSG    C ++
Sbjct: 48  PSGTDDDCFIQ 16

 Score = 78.2 bits (191), Expect = 4e-14,   Method: Compositional matrix adjust.
 Identities = 59/203 (29%), Positives = 84/203 (41%), Gaps = 3/203 (1%)
 Frame = -1

Query: 1266 VKARVANPSGNLTDTYVQDCGDGTYKVEYTPYEEGVHSVDVTYDGXXXXXXXXXXXXTEG 1325
            + A V +PS    D  +Q+  DG Y V + P E GVH+V V Y                 
Sbjct: 639  LAACVTSPSNVTEDAEIQEIEDGLYSVHFVPKELGVHTVSVRYSEMHIPGSPFQFTVGPL 460

Query: 1326 CDPSR--VRVHGPGIQSGTTNKPNKFTXXXXXXXXXXXXXXXXXPSEAKMSCMDNKDGSC 1383
             D     V+  G G++ G   +P +F                  PS+A +   D KDGSC
Sbjct: 459  RDSGSHLVKAGGSGLERGVVGEPAEFNVWTREAGGGSLAISVEGPSKADIEFKDRKDGSC 280

Query: 1384 SVEYIPYEAGTYSLNVTYGGHQVPGSPFKVPVH-DVTDASKVKCSGPGLSPGMVRANLPQ 1442
             V Y   E G Y + + +    +P SPFKV +  D  DA K++        G ++A+ P 
Sbjct: 279  DVSYKVTEPGEYRVGLKFNDRHIPDSPFKVYISPDAGDAHKLEVQ--QFPQGNIQADAPY 106

Query: 1443 SFQVDTSKAGVAPLQVKVQGPKG 1465
             F V  + A    L  K+  P G
Sbjct: 105  QFMVRKNGAK-GELDAKIVAPSG 40

 Score = 78.2 bits (191), Expect = 5e-14,   Method: Compositional matrix adjust.
 Identities = 52/150 (34%), Positives = 83/150 (55%), Gaps = 2/150 (1%)
 Frame = -1

Query: 402 TVEPQLEARGDSTYRCSYQPTMEGVHTVHVTFAGVPIPRSPYTVTVGQACNPAA--CRAI 459
           T + +++   D  Y   + P   GVHTV V ++ + IP SP+  TVG   +  +   +A 
Sbjct: 606 TEDAEIQEIEDGLYSVHFVPKELGVHTVSVRYSEMHIPGSPFQFTVGPLRDSGSHLVKAG 427

Query: 460 GRGLQPKGVRVKETADFKVYTKGAGSGELKVTVKGPKGEERVKQKDLGDGVYGFEYYPTI 519
           G GL+ +GV V E A+F V+T+ AG G L ++V+GP   + ++ KD  DG     Y  T 
Sbjct: 426 GSGLE-RGV-VGEPAEFNVWTREAGGGSLAISVEGPSKAD-IEFKDRKDGSCDVSYKVTE 256

Query: 520 PGTYTVTITWGGQNIGRSPFEVKVGTECGN 549
           PG Y V + +  ++I  SPF+V +  + G+
Sbjct: 255 PGEYRVGLKFNDRHIPDSPFKVYISPDAGD 166

 Score = 73.6 bits (179), Expect = 1e-12,   Method: Compositional matrix adjust.
 Identities = 57/211 (27%), Positives = 91/211 (43%), Gaps = 9/211 (4%)
 Frame = -1

Query: 1553 LAVQITDPEGKPKKTHIQDNHDGTYTVAYVPDVPGRYTILIKYGGDEIPFSPYRVRAVPT 1612
            LA  +T P    +   IQ+  DG Y+V +VP   G +T+ ++Y    IP SP++    P 
Sbjct: 639  LAACVTSPSNVTEDAEIQEIEDGLYSVHFVPKELGVHTVSVRYSEMHIPGSPFQFTVGPL 460

Query: 1613 GDASKCTVTVSIXXXXXXXXXXPTIQIGEETVITVDTKAAGKGKVTCTVCTPDGSXXXXX 1672
             D+    V                  +GE     V T+ AG G +  +V  P  S     
Sbjct: 459  RDSGSHLVKAGGSGLERGV-------VGEPAEFNVWTREAGGGSLAISVEGP--SKADIE 307

Query: 1673 XXXXXXGTFDIFYTAPQPGKYVICVRFGGEHVPNSPFQVTIPERPMVG-VNGLDVTSL-- 1729
                  G+ D+ Y   +PG+Y + ++F   H+P+SPF+V I   P  G  + L+V     
Sbjct: 306  FKDRKDGSCDVSYKVTEPGEYRVGLKFNDRHIPDSPFKVYI--SPDAGDAHKLEVQQFPQ 133

Query: 1730 ------RPFDLVIPFTIKKGEITGEVRMPSG 1754
                   P+  ++     KGE+  ++  PSG
Sbjct: 132  GNIQADAPYQFMVRKNGAKGELDAKIVAPSG 40

 Score = 66.2 bits (160), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 57/196 (29%), Positives = 93/196 (47%), Gaps = 5/196 (2%)
 Frame = -1

Query: 693 EATVKDNGNGTYSCSYVPRKPVKHTAMVSWGGVSIPNSPFRVNVG----AGSHPNKVKVY 748
           +A +++  +G YS  +VP++   HT  V +  + IP SPF+  VG    +GSH   VK  
Sbjct: 600 DAEIQEIEDGLYSVHFVPKELGVHTVSVRYSEMHIPGSPFQFTVGPLRDSGSH--LVKAG 427

Query: 749 GPGVAKTGLKAHEPTYFTVDCTEAGQGDVSIGIKCAPGVVGPTEAXXXXXXXXXXXXTFT 808
           G G+ +  +   EP  F V   EAG G ++I ++      GP++A              +
Sbjct: 426 GSGLERGVVG--EPAEFNVWTREAGGGSLAISVE------GPSKADIEFKDRKDGSCDVS 271

Query: 809 VKYTPCGAGSYTIMVLFADQATPTSPIRVKVEP-SHDASKVKAEGPGLNRTGVELGKPTH 867
            K T    G Y + + F D+  P SP +V + P + DA K++ +     +  ++   P  
Sbjct: 270 YKVTE--PGEYRVGLKFNDRHIPDSPFKVYISPDAGDAHKLEVQ--QFPQGNIQADAPYQ 103

Query: 868 FTVNAKTAGKGKLDVQ 883
           F V  K   KG+LD +
Sbjct: 102 FMVR-KNGAKGELDAK 58

 Score = 65.1 bits (157), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 50/161 (31%), Positives = 77/161 (47%), Gaps = 6/161 (3%)
 Frame = -1

Query: 244 PGAPLRPKLNPKK------ARAYGPGIEPTGNMVKKRAEFTVETRSAGQGEVLVYVEDPA 297
           PG+P +  + P +       +A G G+E    +V + AEF V TR AG G + + VE P+
Sbjct: 495 PGSPFQFTVGPLRDSGSHLVKAGGSGLER--GVVGEPAEFNVWTREAGGGSLAISVEGPS 322

Query: 298 GHQEEAKVTANNDKNRTFSVWYVPEVTGTHKVTVLFAGQHIAKSPFEVYVDKSQGDASKV 357
               +A +   + K+ +  V Y     G ++V + F  +HI  SPF+VY+    GDA K+
Sbjct: 321 ----KADIEFKDRKDGSCDVSYKVTEPGEYRVGLKFNDRHIPDSPFKVYISPDAGDAHKL 154

Query: 358 TAQGPGLEPSGNIANKTTYFEIFTAGAGMGEVEVVIQDPTG 398
             Q     P GNI     Y  +       GE++  I  P+G
Sbjct: 153 EVQ---QFPQGNIQADAPYQFMVRKNGAKGELDAKIVAPSG 40

 Score = 64.7 bits (156), Expect = 5e-10,   Method: Compositional matrix adjust.
 Identities = 56/188 (29%), Positives = 80/188 (42%), Gaps = 3/188 (1%)
 Frame = -1

Query: 2403 LSVTIDGPSKVKMDC--QECPEG-YRVTYTPMAPGSYLISIKYGGPYHIGGSPFKAKVTG 2459
            L+  +  PS V  D   QE  +G Y V + P   G + +S++Y    HI GSPF+  V G
Sbjct: 639  LAACVTSPSNVTEDAEIQEIEDGLYSVHFVPKELGVHTVSVRYS-EMHIPGSPFQFTV-G 466

Query: 2460 PRLVSNHSLHETSSVFVDSLTKVATVPQHATSGPGPADVSKVVAKGLGLSKAYVGQKSNF 2519
            P   S   L                                V A G GL +  VG+ + F
Sbjct: 465  PLRDSGSHL--------------------------------VKAGGSGLERGVVGEPAEF 382

Query: 2520 TVDCSKAGNNMLLVGVHGPRTPCEEILVKHMGSRLYSVSYLLKDKGEYTLVVKWGDEHIP 2579
             V   +AG   L + V GP     E   +  GS    VSY + + GEY + +K+ D HIP
Sbjct: 381  NVWTREAGGGSLAISVEGPSKADIEFKDRKDGS--CDVSYKVTEPGEYRVGLKFNDRHIP 208

Query: 2580 GSPYRIMV 2587
             SP+++ +
Sbjct: 207  DSPFKVYI 184

 Score = 62.4 bits (150), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 62/209 (29%), Positives = 97/209 (46%), Gaps = 4/209 (1%)
 Frame = -1

Query: 293 VEDPAGHQEEAKVTANNDKNRTFSVWYVPEVTGTHKVTVLFAGQHIAKSPFEVYVDKSQG 352
           V  P+   E+A++    D    +SV +VP+  G H V+V ++  HI  SPF+  V   + 
Sbjct: 627 VTSPSNVTEDAEIQEIEDG--LYSVHFVPKELGVHTVSVRYSEMHIPGSPFQFTVGPLRD 454

Query: 353 DASK-VTAQGPGLEPSGNIANKTTYFEIFTAGAGMGEVEVVIQDPTGQKGTVEPQLEARG 411
             S  V A G GLE    +  +   F ++T  AG G + + ++ P+  K  +E   + R 
Sbjct: 453 SGSHLVKAGGSGLER--GVVGEPAEFNVWTREAGGGSLAISVEGPS--KADIE--FKDRK 292

Query: 412 DSTYRCSYQPTMEGVHTVHVTFAGVPIPRSPYTVTVGQACNPAACRAIGRGLQ--PKG-V 468
           D +   SY+ T  G + V + F    IP SP+ V +    +P A  A    +Q  P+G +
Sbjct: 291 DGSCDVSYKVTEPGEYRVGLKFNDRHIPDSPFKVYI----SPDAGDAHKLEVQQFPQGNI 124

Query: 469 RVKETADFKVYTKGAGSGELKVTVKGPKG 497
           +      F V   GA  GEL   +  P G
Sbjct: 123 QADAPYQFMVRKNGA-KGELDAKIVAPSG 40

 Score = 57.4 bits (137), Expect = 8e-08,   Method: Compositional matrix adjust.
 Identities = 49/146 (33%), Positives = 69/146 (47%), Gaps = 4/146 (2%)
 Frame = -1

Query: 891  DAVRDVDIIDHHDNTYTVKYIPVQQGPVGVNVTYGGDHIPKSPFSVGVSPSLD----LSK 946
            +   D +I +  D  Y+V ++P + G   V+V Y   HIP SPF   V P  D    L K
Sbjct: 612  NVTEDAEIQEIEDGLYSVHFVPKELGVHTVSVRYSEMHIPGSPFQFTVGPLRDSGSHLVK 433

Query: 947  IKVSGLGDKVDVGKDQEFTVKSKGAGGQGKVASKIVSPSGAAVPCKVEPGLGADNSVVRF 1006
               SGL   V VG+  EF V ++ AGG G +A  +  PS A +  K       D   V +
Sbjct: 432  AGGSGLERGV-VGEPAEFNVWTREAGG-GSLAISVEGPSKADIEFKDRKDGSCD---VSY 268

Query: 1007 VPREEGPYEVEVTYDGVPVPGSPFPL 1032
               E G Y V + ++   +P SPF +
Sbjct: 267  KVTEPGEYRVGLKFNDRHIPDSPFKV 190
>29446
          Length = 1445

 Score =  204 bits (519), Expect = 4e-52,   Method: Composition-based stats.
 Identities = 101/155 (65%), Positives = 125/155 (80%), Gaps = 3/155 (1%)
 Frame = +3

Query: 3    ATEKDLAEDAPWKKIQQNTFTRWCNEHLKCVSKRIANLQTDLSDGLRLIALLEVLSQKKM 62
            +TE++LAEDA WK IQ+NTFTRW NEHL+ V+K IA+L++D SDGLRL+AL+EVLS KK 
Sbjct: 957  STERELAEDAQWKIIQKNTFTRWANEHLRTVNKAIADLESDFSDGLRLVALIEVLSGKKF 1136

Query: 63   HRKH-NQRPTFRQMQLENVSVALEFL-DRESIKLVSIDSKAIVDGNLKLILGLIWTLILH 120
              KH N+RP FR  +LENV++ L+FL D E I++V+IDS  IVD  LKLILGLIWTLILH
Sbjct: 1137 --KHVNKRPNFRTQKLENVTLTLKFLEDDEGIRIVNIDSTDIVDKKLKLILGLIWTLILH 1310

Query: 121  YSISMPMWDEEEDEEAK-KQTPKQRLLGWIQNKLP 154
            YSISMPMW+ EE   ++   TPKQRLL WIQ+K+P
Sbjct: 1311 YSISMPMWEGEEPTPSEGGPTPKQRLLNWIQSKVP 1415
>19277
          Length = 511

 Score =  178 bits (451), Expect(2) = 1e-49,   Method: Compositional matrix adjust.
 Identities = 86/131 (65%), Positives = 104/131 (79%), Gaps = 2/131 (1%)
 Frame = +2

Query: 1980 ISQSEIGDASRVRVSGQGLHEGHTFEPAEFIIDTRDAGYGGLSLSIEGPSKVDINTEDLE 2039
            + +SE+G+AS+V+VSG GL EG   E  EF++DTR+AGYGG+SLSIEGPSK DI   D E
Sbjct: 77   VGESELGNASKVKVSGDGLTEGMANEVNEFVVDTREAGYGGMSLSIEGPSKADIECHDNE 256

Query: 2040 DGTCRVTYCPTEPGNYIINIKFADQHVPGSPFSVKVTGE--GRVKESITRRRRAPSVANI 2097
            DGTCRVTY PTEPG YIINIKFADQHVPGSP+SVK+ GE   ++ E ITR + A  V ++
Sbjct: 257  DGTCRVTYKPTEPGTYIINIKFADQHVPGSPYSVKIGGEPSTKITERITRHKAAADVTHV 436

Query: 2098 GSHCDLSLKIP 2108
            GS C+LSLKIP
Sbjct: 437  GSQCELSLKIP 469

 Score = 39.7 bits (91), Expect(2) = 1e-49,   Method: Composition-based stats.
 Identities = 15/25 (60%), Positives = 22/25 (88%)
 Frame = +1

Query: 1954 PKETGEHLVHVKKNGQHVASSPIPV 1978
            P+ETGEHLV+V +NG+H+A+SP  +
Sbjct: 1    PRETGEHLVNVYRNGKHIANSPFKI 75

 Score =  113 bits (282), Expect = 1e-24,   Method: Compositional matrix adjust.
 Identities = 55/121 (45%), Positives = 82/121 (67%), Gaps = 2/121 (1%)
 Frame = +2

Query: 1805 NCGHITAYGPGLTHGVVNKPATFTVNTKDAGEGGLSLAIEGPSKAEISCTDNQDGTCSVS 1864
            N   +   G GLT G+ N+   F V+T++AG GG+SL+IEGPSKA+I C DN+DGTC V+
Sbjct: 98   NASKVKVSGDGLTEGMANEVNEFVVDTREAGYGGMSLSIEGPSKADIECHDNEDGTCRVT 277

Query: 1865 YLPVLPGDYSILVKYNDQHIPGSPFTARVTGDDSMRMSH--LKVGSAADIPINISETDLS 1922
            Y P  PG Y I +K+ DQH+PGSP++ ++ G+ S +++    +  +AAD+    S+ +LS
Sbjct: 278  YKPTEPGTYIINIKFADQHVPGSPYSVKIGGEPSTKITERITRHKAAADVTHVGSQCELS 457

Query: 1923 L 1923
            L
Sbjct: 458  L 460

 Score = 88.2 bits (217), Expect(2) = 1e-19,   Method: Compositional matrix adjust.
 Identities = 43/97 (44%), Positives = 62/97 (63%)
 Frame = +2

Query: 2170 TVGPLGEGGAHKVRAGGPGLERAEAGVPAEFGIWTREAGAGGLAIAVEGPSKAEISFEDR 2229
            +VG    G A KV+  G GL    A    EF + TREAG GG+++++EGPSKA+I   D 
Sbjct: 74   SVGESELGNASKVKVSGDGLTEGMANEVNEFVVDTREAGYGGMSLSIEGPSKADIECHDN 253

Query: 2230 KDGSCGVAYVVQEPGDYEVSVKFNEEHIPDSPFVVPV 2266
            +DG+C V Y   EPG Y +++KF ++H+P SP+ V +
Sbjct: 254  EDGTCRVTYKPTEPGTYIINIKFADQHVPGSPYSVKI 364

 Score = 28.9 bits (63), Expect(2) = 1e-19,   Method: Composition-based stats.
 Identities = 12/28 (42%), Positives = 16/28 (57%)
 Frame = +1

Query: 2145 PAEMGMHTVSVKYKGQHVPGSPFQFTVG 2172
            P E G H V+V   G+H+  SPF+   G
Sbjct: 1    PRETGEHLVNVYRNGKHIANSPFKICRG 84

 Score = 90.1 bits (222), Expect(2) = 2e-18,   Method: Compositional matrix adjust.
 Identities = 43/87 (49%), Positives = 52/87 (59%)
 Frame = +2

Query: 1041 SKVKAFGPGLQGGNAGSPARFTIDTKXXXXXXXXXXVEGPCEAQLECLDNGDGTCSVSYV 1100
            SKVK  G GL  G A     F +DT+          +EGP +A +EC DN DGTC V+Y 
Sbjct: 104  SKVKVSGDGLTEGMANEVNEFVVDTREAGYGGMSLSIEGPSKADIECHDNEDGTCRVTYK 283

Query: 1101 PTEPGDYNINILFADTHIPGSPFKAHV 1127
            PTEPG Y INI FAD H+PGSP+   +
Sbjct: 284  PTEPGTYIINIKFADQHVPGSPYSVKI 364

 Score = 22.7 bits (47), Expect(2) = 2e-18,   Method: Composition-based stats.
 Identities = 10/25 (40%), Positives = 14/25 (56%)
 Frame = +1

Query: 1008 PREEGPYEVEVTYDGVPVPGSPFPL 1032
            PRE G + V V  +G  +  SPF +
Sbjct: 1    PRETGEHLVNVYRNGKHIANSPFKI 75

 Score = 73.6 bits (179), Expect(2) = 2e-17,   Method: Compositional matrix adjust.
 Identities = 38/93 (40%), Positives = 57/93 (61%), Gaps = 1/93 (1%)
 Frame = +2

Query: 2368 GDPGLVSAYGAGLEGGVTGSPAEFIVNTSNAGAGALSVTIDGPSKVKMDCQECPEGY-RV 2426
            G+   V   G GL  G+     EF+V+T  AG G +S++I+GPSK  ++C +  +G  RV
Sbjct: 95   GNASKVKVSGDGLTEGMANEVNEFVVDTREAGYGGMSLSIEGPSKADIECHDNEDGTCRV 274

Query: 2427 TYTPMAPGSYLISIKYGGPYHIGGSPFKAKVTG 2459
            TY P  PG+Y+I+IK+    H+ GSP+  K+ G
Sbjct: 275  TYKPTEPGTYIINIKF-ADQHVPGSPYSVKIGG 370

 Score = 36.2 bits (82), Expect(2) = 2e-17,   Method: Composition-based stats.
 Identities = 17/29 (58%), Positives = 20/29 (68%)
 Frame = +1

Query: 2335 PRENGIYLIDVKFNGTHIPGSPFKIRVGE 2363
            PRE G +L++V  NG HI  SPFKI  GE
Sbjct: 1    PRETGEHLVNVYRNGKHIANSPFKICRGE 87

 Score = 69.3 bits (168), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 32/89 (35%), Positives = 47/89 (52%)
 Frame = +2

Query: 1327 DPSRVRVHGPGIQSGTTNKPNKFTXXXXXXXXXXXXXXXXXPSEAKMSCMDNKDGSCSVE 1386
            + S+V+V G G+  G  N+ N+F                  PS+A + C DN+DG+C V 
Sbjct: 98   NASKVKVSGDGLTEGMANEVNEFVVDTREAGYGGMSLSIEGPSKADIECHDNEDGTCRVT 277

Query: 1387 YIPYEAGTYSLNVTYGGHQVPGSPFKVPV 1415
            Y P E GTY +N+ +    VPGSP+ V +
Sbjct: 278  YKPTEPGTYIINIKFADQHVPGSPYSVKI 364

 Score = 68.9 bits (167), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 38/96 (39%), Positives = 58/96 (60%)
 Frame = +2

Query: 1417 DVTDASKVKCSGPGLSPGMVRANLPQSFQVDTSKAGVAPLQVKVQGPKGLVEPVDVVDNA 1476
            ++ +ASKVK SG GL+ GM  AN    F VDT +AG   + + ++GP      ++  DN 
Sbjct: 89   ELGNASKVKVSGDGLTEGM--ANEVNEFVVDTREAGYGGMSLSIEGPSKA--DIECHDNE 256

Query: 1477 DGTQTVNYVPSREGSYSISVLYGEEEVPRSPFKVKV 1512
            DGT  V Y P+  G+Y I++ + ++ VP SP+ VK+
Sbjct: 257  DGTCRVTYKPTEPGTYIINIKFADQHVPGSPYSVKI 364

 Score = 66.6 bits (161), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 43/137 (31%), Positives = 66/137 (48%), Gaps = 1/137 (0%)
 Frame = +2

Query: 545 TECGN-QKVRAWGPGLEGGIVGKSADFVVEAIGDDVGTLGFSVEGPSQAKIECDDKGDGS 603
           +E GN  KV+  G GL  G+  +  +FVV+      G +  S+EGPS+A IEC D  DG+
Sbjct: 86  SELGNASKVKVSGDGLTEGMANEVNEFVVDTREAGYGGMSLSIEGPSKADIECHDNEDGT 265

Query: 604 CDVRYWPQEAGEYAVHVLCNSEDIRLSPFMADIREAPQDFHPDRVKARGPGLEKTGVAVN 663
           C V Y P E G Y +++    + +  SP+   I   P     +R+       + T V   
Sbjct: 266 CRVTYKPTEPGTYIINIKFADQHVPGSPYSVKIGGEPSTKITERITRHKAAADVTHVG-- 439

Query: 664 KPAEFTVDAKHAGKAPL 680
             ++  +  K  G +PL
Sbjct: 440 --SQCELSLKIPGTSPL 484

 Score = 63.9 bits (154), Expect = 8e-10,   Method: Compositional matrix adjust.
 Identities = 36/91 (39%), Positives = 50/91 (54%)
 Frame = +2

Query: 1132 DASKVKCSGPGLERATAGEVGQFQVDCSSAGSAELTIEICSEAGLPAEVYIQDHGDGTHT 1191
            +ASKVK SG GL    A EV +F VD   AG   +++ I  E    A++   D+ DGT  
Sbjct: 98   NASKVKVSGDGLTEGMANEVNEFVVDTREAGYGGMSLSI--EGPSKADIECHDNEDGTCR 271

Query: 1192 ITYIPLCPGAYTVTIKYGGQPVPNFPSKLQV 1222
            +TY P  PG Y + IK+  Q VP  P  +++
Sbjct: 272  VTYKPTEPGTYIINIKFADQHVPGSPYSVKI 364

 Score = 63.2 bits (152), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 40/92 (43%), Positives = 53/92 (57%)
 Frame = +2

Query: 1517 DASKVKASGPGLNTTGVPASLPVEFTIDAKDAGEGLLAVQITDPEGKPKKTHIQDNHDGT 1576
            +ASKVK SG GL T G+ A+   EF +D ++AG G +++ I  P     + H  DN DGT
Sbjct: 98   NASKVKVSGDGL-TEGM-ANEVNEFVVDTREAGYGGMSLSIEGPSKADIECH--DNEDGT 265

Query: 1577 YTVAYVPDVPGRYTILIKYGGDEIPFSPYRVR 1608
              V Y P  PG Y I IK+    +P SPY V+
Sbjct: 266  CRVTYKPTEPGTYIINIKFADQHVPGSPYSVK 361

 Score = 54.7 bits (130), Expect = 5e-07,   Method: Compositional matrix adjust.
 Identities = 45/146 (30%), Positives = 69/146 (47%), Gaps = 5/146 (3%)
 Frame = +2

Query: 830 TPTSPIRVKVEPSH-DASKVKAEGPGLNRTGVELGKPTHFTVNAKTAGKGKLDVQFSGLA 888
           +PT+P R   E    +ASKVK  G GL  T     +   F V+ + AG G + +   G +
Sbjct: 53  SPTAPSRSVGESELGNASKVKVSGDGL--TEGMANEVNEFVVDTREAGYGGMSLSIEGPS 226

Query: 889 KGDAVRDVDIIDHHDNTYTVKYIPVQQGPVGVNVTYGGDHIPKSPFSV--GVSPSLDLSK 946
           K D    ++  D+ D T  V Y P + G   +N+ +   H+P SP+SV  G  PS  +++
Sbjct: 227 KAD----IECHDNEDGTCRVTYKPTEPGTYIINIKFADQHVPGSPYSVKIGGEPSTKITE 394

Query: 947 --IKVSGLGDKVDVGKDQEFTVKSKG 970
              +     D   VG   E ++K  G
Sbjct: 395 RITRHKAAADVTHVGSQCELSLKIPG 472

 Score = 52.0 bits (123), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 34/97 (35%), Positives = 53/97 (54%)
 Frame = +2

Query: 352 GDASKVTAQGPGLEPSGNIANKTTYFEIFTAGAGMGEVEVVIQDPTGQKGTVEPQLEARG 411
           G+ASKV   G GL  +  +AN+   F + T  AG G + + I+ P+  K  +E       
Sbjct: 95  GNASKVKVSGDGL--TEGMANEVNEFVVDTREAGYGGMSLSIEGPS--KADIE--CHDNE 256

Query: 412 DSTYRCSYQPTMEGVHTVHVTFAGVPIPRSPYTVTVG 448
           D T R +Y+PT  G + +++ FA   +P SPY+V +G
Sbjct: 257 DGTCRVTYKPTEPGTYIINIKFADQHVPGSPYSVKIG 367

 Score = 47.4 bits (111), Expect(2) = 4e-06,   Method: Compositional matrix adjust.
 Identities = 29/93 (31%), Positives = 46/93 (49%), Gaps = 1/93 (1%)
 Frame = +2

Query: 2271 GDARRLTVSSLQESGLKVNQPASFAVSLNGA-KGAIDAKVHSPSGALEECYVTEIDQDKY 2329
            G+A ++ VS    +    N+   F V    A  G +   +  PS A  EC+  E      
Sbjct: 95   GNASKVKVSGDGLTEGMANEVNEFVVDTREAGYGGMSLSIEGPSKADIECHDNE--DGTC 268

Query: 2330 AVRFIPRENGIYLIDVKFNGTHIPGSPFKIRVG 2362
             V + P E G Y+I++KF   H+PGSP+ +++G
Sbjct: 269  RVTYKPTEPGTYIINIKFADQHVPGSPYSVKIG 367

 Score = 23.5 bits (49), Expect(2) = 4e-06,   Method: Composition-based stats.
 Identities = 10/24 (41%), Positives = 17/24 (70%)
 Frame = +1

Query: 2241 QEPGDYEVSVKFNEEHIPDSPFVV 2264
            +E G++ V+V  N +HI +SPF +
Sbjct: 4    RETGEHLVNVYRNGKHIANSPFKI 75

 Score = 51.2 bits (121), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 30/95 (31%), Positives = 51/95 (53%)
 Frame = +2

Query: 253 NPKKARAYGPGIEPTGNMVKKRAEFTVETRSAGQGEVLVYVEDPAGHQEEAKVTANNDKN 312
           N  K +  G G+  T  M  +  EF V+TR AG G + + +E P+    +A +  +++++
Sbjct: 98  NASKVKVSGDGL--TEGMANEVNEFVVDTREAGYGGMSLSIEGPS----KADIECHDNED 259

Query: 313 RTFSVWYVPEVTGTHKVTVLFAGQHIAKSPFEVYV 347
            T  V Y P   GT+ + + FA QH+  SP+ V +
Sbjct: 260 GTCRVTYKPTEPGTYIINIKFADQHVPGSPYSVKI 364

 Score = 50.1 bits (118), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 32/95 (33%), Positives = 52/95 (54%)
 Frame = +2

Query: 452 NPAACRAIGRGLQPKGVRVKETADFKVYTKGAGSGELKVTVKGPKGEERVKQKDLGDGVY 511
           N +  +  G GL  +G+   E  +F V T+ AG G + ++++GP   + ++  D  DG  
Sbjct: 98  NASKVKVSGDGLT-EGM-ANEVNEFVVDTREAGYGGMSLSIEGPSKAD-IECHDNEDGTC 268

Query: 512 GFEYYPTIPGTYTVTITWGGQNIGRSPFEVKVGTE 546
              Y PT PGTY + I +  Q++  SP+ VK+G E
Sbjct: 269 RVTYKPTEPGTYIINIKFADQHVPGSPYSVKIGGE 373

 Score = 48.9 bits (115), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 29/104 (27%), Positives = 49/104 (47%)
 Frame = +2

Query: 2484 TVPQHATSGPGPADVSKVVAKGLGLSKAYVGQKSNFTVDCSKAGNNMLLVGVHGPRTPCE 2543
            T P  +       + SKV   G GL++    + + F VD  +AG   + + + GP     
Sbjct: 59   TAPSRSVGESELGNASKVKVSGDGLTEGMANEVNEFVVDTREAGYGGMSLSIEGPSKADI 238

Query: 2544 EILVKHMGSRLYSVSYLLKDKGEYTLVVKWGDEHIPGSPYRIMV 2587
            E      G+    V+Y   + G Y + +K+ D+H+PGSPY + +
Sbjct: 239  ECHDNEDGT--CRVTYKPTEPGTYIINIKFADQHVPGSPYSVKI 364

 Score = 48.1 bits (113), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 46/119 (38%), Positives = 60/119 (50%), Gaps = 4/119 (3%)
 Frame = +2

Query: 728 PNSPFRVNVGAGSHPN--KVKVYGPGVAKTGLKAHEPTYFTVDCTEAGQGDVSIGIKCAP 785
           P +P R +VG     N  KVKV G G+ + G+ A+E   F VD  EAG G +S+ I+   
Sbjct: 56  PTAPSR-SVGESELGNASKVKVSGDGLTE-GM-ANEVNEFVVDTREAGYGGMSLSIE--- 217

Query: 786 GVVGPTEAXXXXXXXXXXXXTFTVKYTPCGAGSYTIMVLFADQATPTSPIRVKV--EPS 842
              GP++A            T  V Y P   G+Y I + FADQ  P SP  VK+  EPS
Sbjct: 218 ---GPSKADIECHDNEDG--TCRVTYKPTEPGTYIINIKFADQHVPGSPYSVKIGGEPS 379

 Score = 43.9 bits (102), Expect = 8e-04,   Method: Compositional matrix adjust.
 Identities = 24/71 (33%), Positives = 36/71 (50%)
 Frame = +2

Query: 1647 VDTKAAGKGKVTCTVCTPDGSXXXXXXXXXXXGTFDIFYTAPQPGKYVICVRFGGEHVPN 1706
            VDT+ AG G ++ ++  P  S           GT  + Y   +PG Y+I ++F  +HVP 
Sbjct: 170  VDTREAGYGGMSLSIEGP--SKADIECHDNEDGTCRVTYKPTEPGTYIINIKFADQHVPG 343

Query: 1707 SPFQVTIPERP 1717
            SP+ V I   P
Sbjct: 344  SPYSVKIGGEP 376

 Score = 42.0 bits (97), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 16/39 (41%), Positives = 26/39 (66%)
 Frame = +2

Query: 1763 DNKDGTVTVRYSPSEAGLHEMDIRYDNMHIPGSPLQFYV 1801
            DN+DGT  V Y P+E G + ++I++ + H+PGSP    +
Sbjct: 248  DNEDGTCRVTYKPTEPGTYIINIKFADQHVPGSPYSVKI 364

 Score = 37.4 bits (85), Expect(2) = 0.003,   Method: Compositional matrix adjust.
 Identities = 34/104 (32%), Positives = 50/104 (48%), Gaps = 5/104 (4%)
 Frame = +2

Query: 935  SVGVSPSLDLSKIKVSGLGDKVDVGKD-QEFTVKSKGAGGQGKVASKIVSPSGAAVPCKV 993
            SVG S   + SK+KVSG G    +  +  EF V ++ A G G ++  I  PS A + C  
Sbjct: 74   SVGESELGNASKVKVSGDGLTEGMANEVNEFVVDTREA-GYGGMSLSIEGPSKADIECH- 247

Query: 994  EPGLGADNS----VVRFVPREEGPYEVEVTYDGVPVPGSPFPLE 1033
                  DN      V + P E G Y + + +    VPGSP+ ++
Sbjct: 248  ------DNEDGTCRVTYKPTEPGTYIINIKFADQHVPGSPYSVK 361

 Score = 23.5 bits (49), Expect(2) = 0.003,   Method: Composition-based stats.
 Identities = 11/25 (44%), Positives = 13/25 (52%)
 Frame = +1

Query: 912 PVQQGPVGVNVTYGGDHIPKSPFSV 936
           P + G   VNV   G HI  SPF +
Sbjct: 1   PRETGEHLVNVYRNGKHIANSPFKI 75

 Score = 38.1 bits (87), Expect = 0.048,   Method: Compositional matrix adjust.
 Identities = 18/58 (31%), Positives = 32/58 (55%)
 Frame = +2

Query: 2115 MTAQVTSPSGKTHEAEIVEGENHTYCIRFVPAEMGMHTVSVKYKGQHVPGSPFQFTVG 2172
            M+  +  PS    + E  + E+ T  + + P E G + +++K+  QHVPGSP+   +G
Sbjct: 200  MSLSIEGPSKA--DIECHDNEDGTCRVTYKPTEPGTYIINIKFADQHVPGSPYSVKIG 367

 Score = 32.3 bits (72), Expect = 2.3,   Method: Composition-based stats.
 Identities = 18/44 (40%), Positives = 24/44 (54%)
 Frame = +1

Query: 321 PEVTGTHKVTVLFAGQHIAKSPFEVYVDKSQGDASKVTAQGPGL 364
           P  TG H V V   G+HIA SPF++     +G+ +    QG GL
Sbjct: 1   PRETGEHLVNVYRNGKHIANSPFKI----CRGERTWQCQQGQGL 120
>21436
          Length = 546

 Score =  153 bits (386), Expect = 1e-36,   Method: Compositional matrix adjust.
 Identities = 84/186 (45%), Positives = 120/186 (64%), Gaps = 3/186 (1%)
 Frame = -1

Query: 699 NGNGTYSCSYVPRKPVKHTAMVSWGGVSIPNSPFRVNVGAGSHPNKVKVYGPGVAKTGLK 758
           N +GTY+C Y+P +PVKHT  V++GGV++PNSPFRV+V   S P+KVK+ GPGV   G+K
Sbjct: 546 NRDGTYACRYMPLRPVKHTVSVNFGGVAVPNSPFRVHVAEPSDPSKVKISGPGVTN-GIK 370

Query: 759 AHEPTYFTVDCTEAGQGDVSIGIKCAPGVVGPTEAXXXXXXXXXXXXTFTVKYTPCGAGS 818
              PTYFTVDC +AG GDV++G+    G+  P +             TFTV+Y P   G+
Sbjct: 369 TMSPTYFTVDCKQAGPGDVAVGLTDGRGMDVPVKT------TGNQDGTFTVEYEPKLPGT 208

Query: 819 YTIMVLFADQATPTSPIRVKVEPSHDASKVKAEGPGLNRTGVELGKPTHFTVNAKT---A 875
           YT+MV FAD   P+SP++VKVEP+ D S ++ +G   +R  +E   P+ F V+A      
Sbjct: 207 YTVMVYFADVEVPSSPVKVKVEPNIDVSSIRVDGLD-SRVFIE--APSEFVVDASVLDPK 37

Query: 876 GKGKLD 881
           G+G+++
Sbjct: 36  GQGEVE 19

 Score =  112 bits (279), Expect = 3e-24,   Method: Compositional matrix adjust.
 Identities = 67/185 (36%), Positives = 97/185 (52%), Gaps = 1/185 (0%)
 Frame = -1

Query: 1090 NGDGTCSVSYVPTEPGDYNINILFADTHIPGSPFKAHVAPCFDASKVKCSGPGLERAT-A 1148
            N DGT +  Y+P  P  + +++ F    +P SPF+ HVA   D SKVK SGPG+      
Sbjct: 546  NRDGTYACRYMPLRPVKHTVSVNFGGVAVPNSPFRVHVAEPSDPSKVKISGPGVTNGIKT 367

Query: 1149 GEVGQFQVDCSSAGSAELTIEICSEAGLPAEVYIQDHGDGTHTITYIPLCPGAYTVTIKY 1208
                 F VDC  AG  ++ + +    G+   V    + DGT T+ Y P  PG YTV + +
Sbjct: 366  MSPTYFTVDCKQAGPGDVAVGLTDGRGMDVPVKTTGNQDGTFTVEYEPKLPGTYTVMVYF 187

Query: 1209 GGQPVPNFPSKLQVEPAVDTSGVQCYGPGIEGQGVFREATTEFSVDARALTQTGGPHVKA 1268
                VP+ P K++VEP +D S ++    G++ + VF EA +EF VDA  L   G   V+A
Sbjct: 186  ADVEVPSSPVKVKVEPNIDVSSIRV--DGLDSR-VFIEAPSEFVVDASVLDPKGQGEVEA 16

Query: 1269 RVANP 1273
             +  P
Sbjct: 15   ILTTP 1

 Score =  110 bits (274), Expect = 9e-24,   Method: Compositional matrix adjust.
 Identities = 70/186 (37%), Positives = 104/186 (55%), Gaps = 3/186 (1%)
 Frame = -1

Query: 1378 NKDGSCSVEYIPYEAGTYSLNVTYGGHQVPGSPFKVPVHDVTDASKVKCSGPGLSPGMVR 1437
            N+DG+ +  Y+P     ++++V +GG  VP SPF+V V + +D SKVK SGPG++ G ++
Sbjct: 546  NRDGTYACRYMPLRPVKHTVSVNFGGVAVPNSPFRVHVAEPSDPSKVKISGPGVTNG-IK 370

Query: 1438 ANLPQSFQVDTSKAGVAPLQVKVQGPKGLVEPVDVVDNADGTQTVNYVPSREGSYSISVL 1497
               P  F VD  +AG   + V +   +G+  PV    N DGT TV Y P   G+Y++ V 
Sbjct: 369  TMSPTYFTVDCKQAGPGDVAVGLTDGRGMDVPVKTTGNQDGTFTVEYEPKLPGTYTVMVY 190

Query: 1498 YGEEEVPRSPFKVKVLPTHDASKVKASGPGLNTTGVPASLPVEFTIDAK---DAGEGLLA 1554
            + + EVP SP KVKV P  D S ++    GL++  V    P EF +DA      G+G + 
Sbjct: 189  FADVEVPSSPVKVKVEPNIDVSSIRVD--GLDSR-VFIEAPSEFVVDASVLDPKGQGEVE 19

Query: 1555 VQITDP 1560
              +T P
Sbjct: 18   AILTTP 1

 Score =  109 bits (273), Expect = 1e-23,   Method: Compositional matrix adjust.
 Identities = 62/146 (42%), Positives = 82/146 (56%)
 Frame = -1

Query: 1475 NADGTQTVNYVPSREGSYSISVLYGEEEVPRSPFKVKVLPTHDASKVKASGPGLNTTGVP 1534
            N DGT    Y+P R   +++SV +G   VP SPF+V V    D SKVK SGPG+ T G+ 
Sbjct: 546  NRDGTYACRYMPLRPVKHTVSVNFGGVAVPNSPFRVHVAEPSDPSKVKISGPGV-TNGIK 370

Query: 1535 ASLPVEFTIDAKDAGEGLLAVQITDPEGKPKKTHIQDNHDGTYTVAYVPDVPGRYTILIK 1594
               P  FT+D K AG G +AV +TD  G         N DGT+TV Y P +PG YT+++ 
Sbjct: 369  TMSPTYFTVDCKQAGPGDVAVGLTDGRGMDVPVKTTGNQDGTFTVEYEPKLPGTYTVMVY 190

Query: 1595 YGGDEIPFSPYRVRAVPTGDASKCTV 1620
            +   E+P SP +V+  P  D S   V
Sbjct: 189  FADVEVPSSPVKVKVEPNIDVSSIRV 112

 Score = 97.1 bits (240), Expect = 9e-20,   Method: Compositional matrix adjust.
 Identities = 66/182 (36%), Positives = 93/182 (51%), Gaps = 3/182 (1%)
 Frame = -1

Query: 806 TFTVKYTPCGAGSYTIMVLFADQATPTSPIRVKVEPSHDASKVKAEGPGLNRTGVELGKP 865
           T+  +Y P     +T+ V F   A P SP RV V    D SKVK  GPG+   G++   P
Sbjct: 534 TYACRYMPLRPVKHTVSVNFGGVAVPNSPFRVHVAEPSDPSKVKISGPGVTN-GIKTMSP 358

Query: 866 THFTVNAKTAGKGKLDVQFSGLAKGDAVR-DVDIIDHHDNTYTVKYIPVQQGPVGVNVTY 924
           T+FTV+ K AG G + V   GL  G  +   V    + D T+TV+Y P   G   V V +
Sbjct: 357 TYFTVDCKQAGPGDVAV---GLTDGRGMDVPVKTTGNQDGTFTVEYEPKLPGTYTVMVYF 187

Query: 925 GGDHIPKSPFSVGVSPSLDLSKIKVSGLGDKVDVGKDQEFTVKSK--GAGGQGKVASKIV 982
               +P SP  V V P++D+S I+V GL  +V +    EF V +      GQG+V + + 
Sbjct: 186 ADVEVPSSPVKVKVEPNIDVSSIRVDGLDSRVFIEAPSEFVVDASVLDPKGQGEVEAILT 7

Query: 983 SP 984
           +P
Sbjct: 6   TP 1

 Score = 83.2 bits (204), Expect = 1e-15,   Method: Compositional matrix adjust.
 Identities = 54/158 (34%), Positives = 73/158 (46%), Gaps = 3/158 (1%)
 Frame = -1

Query: 1005 RFVPREEGPYEVEVTYDGVPVPGSPFPLEAVAPTKPSKVKAFGPGLQGG-NAGSPARFTI 1063
            R++P     + V V + GV VP SPF +    P+ PSKVK  GPG+  G    SP  FT+
Sbjct: 522  RYMPLRPVKHTVSVNFGGVAVPNSPFRVHVAEPSDPSKVKISGPGVTNGIKTMSPTYFTV 343

Query: 1064 DTKXXXXXXXXXXVEG--PCEAQLECLDNGDGTCSVSYVPTEPGDYNINILFADTHIPGS 1121
            D K          +      +  ++   N DGT +V Y P  PG Y + + FAD  +P S
Sbjct: 342  DCKQAGPGDVAVGLTDGRGMDVPVKTTGNQDGTFTVEYEPKLPGTYTVMVYFADVEVPSS 163

Query: 1122 PFKAHVAPCFDASKVKCSGPGLERATAGEVGQFQVDCS 1159
            P K  V P  D S ++  G    R       +F VD S
Sbjct: 162  PVKVKVEPNIDVSSIRVDGLD-SRVFIEAPSEFVVDAS 52

 Score = 82.8 bits (203), Expect = 2e-15,   Method: Compositional matrix adjust.
 Identities = 55/165 (33%), Positives = 82/165 (49%), Gaps = 2/165 (1%)
 Frame = -1

Query: 412 DSTYRCSYQPTMEGVHTVHVTFAGVPIPRSPYTVTVGQACNPAACRAIGRGLQPKGVRVK 471
           D TY C Y P     HTV V F GV +P SP+ V V +  +P+  +  G G+   G++  
Sbjct: 540 DGTYACRYMPLRPVKHTVSVNFGGVAVPNSPFRVHVAEPSDPSKVKISGPGVT-NGIKTM 364

Query: 472 ETADFKVYTKGAGSGELKVTVKGPKGEER-VKQKDLGDGVYGFEYYPTIPGTYTVTITWG 530
               F V  K AG G++ V +   +G +  VK     DG +  EY P +PGTYTV + + 
Sbjct: 363 SPTYFTVDCKQAGPGDVAVGLTDGRGMDVPVKTTGNQDGTFTVEYEPKLPGTYTVMVYFA 184

Query: 531 GQNIGRSPFEVKVGTECGNQKVRAWGPGLEGGI-VGKSADFVVEA 574
              +  SP +VKV        +R    GL+  + +   ++FVV+A
Sbjct: 183 DVEVPSSPVKVKVEPNIDVSSIRVD--GLDSRVFIEAPSEFVVDA 55

 Score = 82.0 bits (201), Expect = 3e-15,   Method: Compositional matrix adjust.
 Identities = 53/177 (29%), Positives = 93/177 (52%), Gaps = 4/177 (2%)
 Frame = -1

Query: 1764 NKDGTVTVRYSPSEAGLHEMDIRYDNMHIPGSPLQFYV-DYVNCGHITAYGPGLTHGV-V 1821
            N+DGT   RY P     H + + +  + +P SP + +V +  +   +   GPG+T+G+  
Sbjct: 546  NRDGTYACRYMPLRPVKHTVSVNFGGVAVPNSPFRVHVAEPSDPSKVKISGPGVTNGIKT 367

Query: 1822 NKPATFTVNTKDAGEGGLSLAIEGPSKAEI--SCTDNQDGTCSVSYLPVLPGDYSILVKY 1879
              P  FTV+ K AG G +++ +      ++    T NQDGT +V Y P LPG Y+++V +
Sbjct: 366  MSPTYFTVDCKQAGPGDVAVGLTDGRGMDVPVKTTGNQDGTFTVEYEPKLPGTYTVMVYF 187

Query: 1880 NDQHIPGSPFTARVTGDDSMRMSHLKVGSAADIPINISETDLSLLTATVVPPSGREE 1936
             D  +P SP   +V  + ++ +S ++V    D  + I      ++ A+V+ P G+ E
Sbjct: 186  ADVEVPSSPVKVKV--EPNIDVSSIRV-DGLDSRVFIEAPSEFVVDASVLDPKGQGE 25

 Score = 78.6 bits (192), Expect = 3e-14,   Method: Compositional matrix adjust.
 Identities = 57/180 (31%), Positives = 84/180 (46%), Gaps = 3/180 (1%)
 Frame = -1

Query: 601 DGSCDVRYWPQEAGEYAVHVLCNSEDIRLSPFMADIREAPQDFHPDRVKARGPGLEKTGV 660
           DG+   RY P    ++ V V      +  SPF   + E P D  P +VK  GPG+   G+
Sbjct: 540 DGTYACRYMPLRPVKHTVSVNFGGVAVPNSPFRVHVAE-PSD--PSKVKISGPGVTN-GI 373

Query: 661 AVNKPAEFTVDAKHAGKAPLRVQVQDNEGCSVEATVKDNGNGTYSCSYVPRKPVKHTAMV 720
               P  FTVD K AG   + V + D  G  V      N +GT++  Y P+ P  +T MV
Sbjct: 372 KTMSPTYFTVDCKQAGPGDVAVGLTDGRGMDVPVKTTGNQDGTFTVEYEPKLPGTYTVMV 193

Query: 721 SWGGVSIPNSPFRVNVGAGSHPNKVKVYGPGVAKTGLKAHEPTYFTVDCT---EAGQGDV 777
            +  V +P+SP +V V      + ++V G     + +    P+ F VD +     GQG+V
Sbjct: 192 YFADVEVPSSPVKVKVEPNIDVSSIRVDG---LDSRVFIEAPSEFVVDASVLDPKGQGEV 22

 Score = 71.2 bits (173), Expect = 5e-12,   Method: Compositional matrix adjust.
 Identities = 47/135 (34%), Positives = 69/135 (51%), Gaps = 3/135 (2%)
 Frame = -1

Query: 1944 RNGHVGISFVPKETGEHLVHVKKNGQHVASSPIPVVISQSEIGDASRVRVSGQGLHEG-H 2002
            R+G     ++P    +H V V   G  V +SP  V ++  E  D S+V++SG G+  G  
Sbjct: 543  RDGTYACRYMPLRPVKHTVSVNFGGVAVPNSPFRVHVA--EPSDPSKVKISGPGVTNGIK 370

Query: 2003 TFEPAEFIIDTRDAGYGGLSLSIEGPSKVDI--NTEDLEDGTCRVTYCPTEPGNYIINIK 2060
            T  P  F +D + AG G +++ +     +D+   T   +DGT  V Y P  PG Y + + 
Sbjct: 369  TMSPTYFTVDCKQAGPGDVAVGLTDGRGMDVPVKTTGNQDGTFTVEYEPKLPGTYTVMVY 190

Query: 2061 FADQHVPGSPFSVKV 2075
            FAD  VP SP  VKV
Sbjct: 189  FADVEVPSSPVKVKV 145

 Score = 70.9 bits (172), Expect = 6e-12,   Method: Compositional matrix adjust.
 Identities = 57/193 (29%), Positives = 89/193 (46%)
 Frame = -1

Query: 310 DKNRTFSVWYVPEVTGTHKVTVLFAGQHIAKSPFEVYVDKSQGDASKVTAQGPGLEPSGN 369
           +++ T++  Y+P     H V+V F G  +  SPF V+V +   D SKV   GPG+  +G 
Sbjct: 546 NRDGTYACRYMPLRPVKHTVSVNFGGVAVPNSPFRVHVAEPS-DPSKVKISGPGVT-NGI 373

Query: 370 IANKTTYFEIFTAGAGMGEVEVVIQDPTGQKGTVEPQLEARGDSTYRCSYQPTMEGVHTV 429
                TYF +    AG G+V V + D  G+   V  +     D T+   Y+P + G +TV
Sbjct: 372 KTMSPTYFTVDCKQAGPGDVAVGLTD--GRGMDVPVKTTGNQDGTFTVEYEPKLPGTYTV 199

Query: 430 HVTFAGVPIPRSPYTVTVGQACNPAACRAIGRGLQPKGVRVKETADFKVYTKGAGSGELK 489
            V FA V +P SP  V V    + ++ R  G              D +V+ +      + 
Sbjct: 198 MVYFADVEVPSSPVKVKVEPNIDVSSIRVDG-------------LDSRVFIEAPSEFVVD 58

Query: 490 VTVKGPKGEERVK 502
            +V  PKG+  V+
Sbjct: 57  ASVLDPKGQGEVE 19

 Score = 67.4 bits (163), Expect = 7e-11,   Method: Compositional matrix adjust.
 Identities = 48/158 (30%), Positives = 68/158 (43%)
 Frame = -1

Query: 1572 NHDGTYTVAYVPDVPGRYTILIKYGGDEIPFSPYRVRAVPTGDASKCTVTVSIXXXXXXX 1631
            N DGTY   Y+P  P ++T+ + +GG  +P SP+RV      D SK  ++          
Sbjct: 546  NRDGTYACRYMPLRPVKHTVSVNFGGVAVPNSPFRVHVAEPSDPSKVKIS--------GP 391

Query: 1632 XXXPTIQIGEETVITVDTKAAGKGKVTCTVCTPDGSXXXXXXXXXXXGTFDIFYTAPQPG 1691
                 I+    T  TVD K AG G V   +    G            GTF + Y    PG
Sbjct: 390  GVTNGIKTMSPTYFTVDCKQAGPGDVAVGLTDGRGMDVPVKTTGNQDGTFTVEYEPKLPG 211

Query: 1692 KYVICVRFGGEHVPNSPFQVTIPERPMVGVNGLDVTSL 1729
             Y + V F    VP+SP +V +   P + V+ + V  L
Sbjct: 210  TYTVMVYFADVEVPSSPVKVKV--EPNIDVSSIRVDGL 103

 Score = 67.0 bits (162), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 56/183 (30%), Positives = 84/183 (45%), Gaps = 3/183 (1%)
 Frame = -1

Query: 2138 TYCIRFVPAEMGMHTVSVKYKGQHVPGSPFQFTVGPLGEGGAHKVRAGGPGLERA-EAGV 2196
            TY  R++P     HTVSV + G  VP SPF+  V    +    KV+  GPG+    +   
Sbjct: 534  TYACRYMPLRPVKHTVSVNFGGVAVPNSPFRVHVAEPSD--PSKVKISGPGVTNGIKTMS 361

Query: 2197 PAEFGIWTREAGAGGLAIAVEGPSKAEISFED--RKDGSCGVAYVVQEPGDYEVSVKFNE 2254
            P  F +  ++AG G +A+ +      ++  +    +DG+  V Y  + PG Y V V F +
Sbjct: 360  PTYFTVDCKQAGPGDVAVGLTDGRGMDVPVKTTGNQDGTFTVEYEPKLPGTYTVMVYFAD 181

Query: 2255 EHIPDSPFVVPVASPSGDARRLTVSSLQESGLKVNQPASFAVSLNGAKGAIDAKVHSPSG 2314
              +P SP  V V  P+ D   + V  L +S + +  P+ F V         DA V  P G
Sbjct: 180  VEVPSSPVKVKV-EPNIDVSSIRVDGL-DSRVFIEAPSEFVV---------DASVLDPKG 34

Query: 2315 ALE 2317
              E
Sbjct: 33   QGE 25

 Score = 65.9 bits (159), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 50/166 (30%), Positives = 68/166 (40%), Gaps = 3/166 (1%)
 Frame = -1

Query: 1287 DGTYKVEYTPYEEGVHSVDVTYDGXXXXXXXXXXXXTEGCDPSRVRVHGPGIQSGT-TNK 1345
            DGTY   Y P     H+V V + G             E  DPS+V++ GPG+ +G  T  
Sbjct: 540  DGTYACRYMPLRPVKHTVSVNFGGVAVPNSPFRVHVAEPSDPSKVKISGPGVTNGIKTMS 361

Query: 1346 PNKFTXXXXXX--XXXXXXXXXXXPSEAKMSCMDNKDGSCSVEYIPYEAGTYSLNVTYGG 1403
            P  FT                     +  +    N+DG+ +VEY P   GTY++ V +  
Sbjct: 360  PTYFTVDCKQAGPGDVAVGLTDGRGMDVPVKTTGNQDGTFTVEYEPKLPGTYTVMVYFAD 181

Query: 1404 HQVPGSPFKVPVHDVTDASKVKCSGPGLSPGMVRANLPQSFQVDTS 1449
             +VP SP KV V    D S ++  G       V    P  F VD S
Sbjct: 180  VEVPSSPVKVKVEPNIDVSSIRVDG---LDSRVFIEAPSEFVVDAS 52

 Score = 60.5 bits (145), Expect = 9e-09,   Method: Compositional matrix adjust.
 Identities = 52/158 (32%), Positives = 73/158 (46%), Gaps = 7/158 (4%)
 Frame = -1

Query: 2329 YAVRFIPRENGIYLIDVKFNGTHIPGSPFKIRVGEPGHGGDPGLVSAYGAGLEGGV-TGS 2387
            YA R++P     + + V F G  +P SPF++ V EP    DP  V   G G+  G+ T S
Sbjct: 531  YACRYMPLRPVKHTVSVNFGGVAVPNSPFRVHVAEPS---DPSKVKISGPGVTNGIKTMS 361

Query: 2388 PAEFIVNTSNAGAGALSVTI-DGPSKVKMDCQECPEG-----YRVTYTPMAPGSYLISIK 2441
            P  F V+   AG G ++V + DG     MD      G     + V Y P  PG+Y + + 
Sbjct: 360  PTYFTVDCKQAGPGDVAVGLTDGRG---MDVPVKTTGNQDGTFTVEYEPKLPGTYTVMV- 193

Query: 2442 YGGPYHIGGSPFKAKVTGPRLVSNHSLHETSSVFVDSL 2479
            Y     +  SP K KV  P +       + SS+ VD L
Sbjct: 192  YFADVEVPSSPVKVKVE-PNI-------DVSSIRVDGL 103

 Score = 58.9 bits (141), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 47/131 (35%), Positives = 64/131 (48%), Gaps = 2/131 (1%)
 Frame = -1

Query: 901  HHDNTYTVKYIPVQQGPVGVNVTYGGDHIPKSPFSVGVSPSLDLSKIKVSGLG--DKVDV 958
            + D TY  +Y+P++     V+V +GG  +P SPF V V+   D SK+K+SG G  + +  
Sbjct: 546  NRDGTYACRYMPLRPVKHTVSVNFGGVAVPNSPFRVHVAEPSDPSKVKISGPGVTNGIKT 367

Query: 959  GKDQEFTVKSKGAGGQGKVASKIVSPSGAAVPCKVEPGLGADNSVVRFVPREEGPYEVEV 1018
                 FTV  K A G G VA  +    G  VP K   G       V + P+  G Y V V
Sbjct: 366  MSPTYFTVDCKQA-GPGDVAVGLTDGRGMDVPVKTT-GNQDGTFTVEYEPKLPGTYTVMV 193

Query: 1019 TYDGVPVPGSP 1029
             +  V VP SP
Sbjct: 192  YFADVEVPSSP 160

 Score = 53.5 bits (127), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 52/170 (30%), Positives = 79/170 (46%), Gaps = 3/170 (1%)
 Frame = -1

Query: 2230 KDGSCGVAYVVQEPGDYEVSVKFNEEHIPDSPFVVPVASPSGDARRLTVSSLQESGLKVN 2289
            +DG+    Y+   P  + VSV F    +P+SPF V VA PS  ++         +G+K  
Sbjct: 543  RDGTYACRYMPLRPVKHTVSVNFGGVAVPNSPFRVHVAEPSDPSKVKISGPGVTNGIKTM 364

Query: 2290 QPASFAVSLNGAKGAIDAKVHSPSG-ALEECYVTEIDQD-KYAVRFIPRENGIYLIDVKF 2347
             P  F V    A G  D  V    G  ++    T  +QD  + V + P+  G Y + V F
Sbjct: 363  SPTYFTVDCKQA-GPGDVAVGLTDGRGMDVPVKTTGNQDGTFTVEYEPKLPGTYTVMVYF 187

Query: 2348 NGTHIPGSPFKIRVGEPGHGGDPGLVSAYGAGLEGGV-TGSPAEFIVNTS 2396
                +P SP K++V EP    +  + S    GL+  V   +P+EF+V+ S
Sbjct: 186  ADVEVPSSPVKVKV-EP----NIDVSSIRVDGLDSRVFIEAPSEFVVDAS 52

 Score = 49.7 bits (117), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 40/132 (30%), Positives = 64/132 (48%), Gaps = 8/132 (6%)
 Frame = -1

Query: 1679 GTFDIFYTAPQPGKYVICVRFGGEHVPNSPFQVTI--PERP-MVGVNGLDVTSLRPFDLV 1735
            GT+   Y   +P K+ + V FGG  VPNSPF+V +  P  P  V ++G  VT+       
Sbjct: 537  GTYACRYMPLRPVKHTVSVNFGGVAVPNSPFRVHVAEPSDPSKVKISGPGVTNGIKTMSP 358

Query: 1736 IPFTIK-----KGEITGEVRMPSGKVAQPSITDNKDGTVTVRYSPSEAGLHEMDIRYDNM 1790
              FT+       G++   +    G       T N+DGT TV Y P   G + + + + ++
Sbjct: 357  TYFTVDCKQAGPGDVAVGLTDGRGMDVPVKTTGNQDGTFTVEYEPKLPGTYTVMVYFADV 178

Query: 1791 HIPGSPLQFYVD 1802
             +P SP++  V+
Sbjct: 177  EVPSSPVKVKVE 142

 Score = 47.0 bits (110), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 46/167 (27%), Positives = 71/167 (42%), Gaps = 3/167 (1%)
 Frame = -1

Query: 2424 YRVTYTPMAPGSYLISIKYGGPYHIGGSPFKAKVTGPRLVSNHSLHETSSVFVDSLTKVA 2483
            Y   Y P+ P  + +S+ +GG   +  SPF+  V  P   S   +               
Sbjct: 531  YACRYMPLRPVKHTVSVNFGG-VAVPNSPFRVHVAEPSDPSKVKI--------------- 400

Query: 2484 TVPQHATSGPGPADVSKVVAKGLG-LSKAYVGQKSNFTVDCSKAGNNMLLVGVHGPRTPC 2542
                   SGPG       V  G+  +S  Y      FTVDC +AG   + VG+   R   
Sbjct: 399  -------SGPG-------VTNGIKTMSPTY------FTVDCKQAGPGDVAVGLTDGR--G 286

Query: 2543 EEILVKHMGSR--LYSVSYLLKDKGEYTLVVKWGDEHIPGSPYRIMV 2587
             ++ VK  G++   ++V Y  K  G YT++V + D  +P SP ++ V
Sbjct: 285  MDVPVKTTGNQDGTFTVEYEPKLPGTYTVMVYFADVEVPSSPVKVKV 145
>19002
          Length = 842

 Score =  102 bits (255), Expect = 2e-21,   Method: Composition-based stats.
 Identities = 65/195 (33%), Positives = 103/195 (52%), Gaps = 3/195 (1%)
 Frame = -2

Query: 46  DGLRLIALLEVLSQKKMHRKHNQRPTFRQMQLENVSVALEFLDRESIKLVSIDSKAIVDG 105
           DG  L+ LLEV  + ++    + +   R   LENV  AL FL  + + L ++ +  IVDG
Sbjct: 841 DGKMLMKLLEVRVRGEI--ASDXKGKMRIHCLENVDKALTFLHEQRVHLENMGAHDIVDG 668

Query: 106 NLKLILGLIWTLILHYSISMPMWDEEEDEEAKKQTPKQRLLGWIQNK---LPQLPITNFS 162
           + +L LGLIWT+IL + I   M +E ++ E K  + K  LL W Q K    P + + NF+
Sbjct: 667 SSRLTLGLIWTIILRFQIQDIMIEEVDNSETK--SAKDALLLWCQMKTAGYPNVNVRNFT 494

Query: 163 RDWQSGRALGALVDSCAPGLCPDWDSWDASKPVNNAREAMQQADDWLGIPQVITPEEIVD 222
             W+ G A  A++    P L   +D    S  + N + A   A+D LG+  ++ PE++  
Sbjct: 493 TSWRDGLAFNAIIHKHRPDLV-QYDRLHKSSAIQNLQNAFTVAEDKLGLTALLEPEDVNV 317

Query: 223 PNVDEHSVMTYLSQF 237
              DE S++TY+  +
Sbjct: 316 EYPDEKSIITYVVTY 272
>27230
          Length = 583

 Score = 58.2 bits (139), Expect(2) = 6e-17,   Method: Compositional matrix adjust.
 Identities = 33/85 (38%), Positives = 46/85 (54%), Gaps = 3/85 (3%)
 Frame = -2

Query: 1368 PSEAKMSCMDNKDGSCSVEYIPYEAGTYSLNVTYGGHQVPGSPFK---VPVHDVTDASKV 1424
            P ++K++C++  DG+ +V YIP   G Y + V++G   VPGSPF     P     D S +
Sbjct: 519  PEKSKINCVNXDDGTVNVTYIPEFPGEYKVKVSHGDKPVPGSPFTALITPSELDPDVSSI 340

Query: 1425 KCSGPGLSPGMVRANLPQSFQVDTS 1449
              SG G+SP  V    P  F VD S
Sbjct: 339  TASGYGISPEGVFIEAPSEFVVDAS 265

 Score = 50.1 bits (118), Expect(2) = 6e-17,   Method: Compositional matrix adjust.
 Identities = 27/58 (46%), Positives = 36/58 (62%), Gaps = 1/58 (1%)
 Frame = -1

Query: 1472 VVDNA-DGTQTVNYVPSREGSYSISVLYGEEEVPRSPFKVKVLPTHDASKVKASGPGL 1528
            +VDN  DGT  V Y P  EG  S+ V Y    +P SPF+V  +  +DA++V+A GPGL
Sbjct: 190  LVDNMKDGTYPVLYTPMEEGPQSLDVTYKGIPIPGSPFQVNAVAGYDANRVRAYGPGL 17

 Score = 55.8 bits (133), Expect(2) = 1e-16,   Method: Compositional matrix adjust.
 Identities = 33/86 (38%), Positives = 46/86 (53%), Gaps = 2/86 (2%)
 Frame = -2

Query: 589 PSQAKIECDDKGDGSCDVRYWPQEAGEYAVHVLCNSEDIRLSPFMADIREAPQDFHPD-- 646
           P ++KI C +  DG+ +V Y P+  GEY V V    + +  SPF A I   P +  PD  
Sbjct: 519 PEKSKINCVNXDDGTVNVTYIPEFPGEYKVKVSHGDKPVPGSPFTALI--TPSELDPDVS 346

Query: 647 RVKARGPGLEKTGVAVNKPAEFTVDA 672
            + A G G+   GV +  P+EF VDA
Sbjct: 345 SITASGYGISPEGVFIEAPSEFVVDA 268

 Score = 50.8 bits (120), Expect(2) = 1e-16,   Method: Compositional matrix adjust.
 Identities = 24/64 (37%), Positives = 37/64 (57%)
 Frame = -1

Query: 689 GCSVEATVKDNGNGTYSCSYVPRKPVKHTAMVSWGGVSIPNSPFRVNVGAGSHPNKVKVY 748
           G  ++  V +  +GTY   Y P +    +  V++ G+ IP SPF+VN  AG   N+V+ Y
Sbjct: 208 GRKLQTLVDNMKDGTYPVLYTPMEEGPQSLDVTYKGIPIPGSPFQVNAVAGYDANRVRAY 29

Query: 749 GPGV 752
           GPG+
Sbjct: 28  GPGL 17

 Score = 68.9 bits (167), Expect(2) = 2e-16,   Method: Compositional matrix adjust.
 Identities = 35/81 (43%), Positives = 53/81 (65%)
 Frame = -1

Query: 973  GQGKVASKIVSPSGAAVPCKVEPGLGADNSVVRFVPREEGPYEVEVTYDGVPVPGSPFPL 1032
            GQG+V + + +PSG  +   V+  +      V + P EEGP  ++VTY G+P+PGSPF +
Sbjct: 247  GQGEVEAILTTPSGRKLQTLVD-NMKDGTYPVLYTPMEEGPQSLDVTYKGIPIPGSPFQV 71

Query: 1033 EAVAPTKPSKVKAFGPGLQGG 1053
             AVA    ++V+A+GPGL+GG
Sbjct: 70   NAVAGYDANRVRAYGPGLEGG 8

 Score = 37.0 bits (84), Expect(2) = 2e-16,   Method: Compositional matrix adjust.
 Identities = 26/80 (32%), Positives = 40/80 (50%), Gaps = 6/80 (7%)
 Frame = -2

Query: 896 VDIIDHHDNTYTVKYIPVQQGPVGVNVTYGGDHIPKSPFSVGVSPSL---DLSKIKVSGL 952
           ++ ++  D T  V YIP   G   V V++G   +P SPF+  ++PS    D+S I  SG 
Sbjct: 504 INCVNXDDGTVNVTYIPEFPGEYKVKVSHGDKPVPGSPFTALITPSELDPDVSSITASGY 325

Query: 953 G---DKVDVGKDQEFTVKSK 969
           G   + V +    EF V + 
Sbjct: 324 GISPEGVFIEAPSEFVVDAS 265

 Score = 55.5 bits (132), Expect(2) = 7e-15,   Method: Compositional matrix adjust.
 Identities = 34/94 (36%), Positives = 49/94 (52%), Gaps = 9/94 (9%)
 Frame = -2

Query: 1470 VDVVDNADGTQTVNYVPSREGSYSISVLYGEEEVPRSPFKVKVLPTH---DASKVKASGP 1526
            ++ V+  DGT  V Y+P   G Y + V +G++ VP SPF   + P+    D S + ASG 
Sbjct: 504  INCVNXDDGTVNVTYIPEFPGEYKVKVSHGDKPVPGSPFTALITPSELDPDVSSITASGY 325

Query: 1527 GLNTTGVPASLPVEFTIDA------KDAGEGLLA 1554
            G++  GV    P EF +DA      KD G   L+
Sbjct: 324  GISPEGVFIEAPSEFVVDASVLDP*KDKGRWRLS 223

 Score = 45.4 bits (106), Expect(2) = 7e-15,   Method: Compositional matrix adjust.
 Identities = 25/70 (35%), Positives = 39/70 (55%)
 Frame = -1

Query: 1549 GEGLLAVQITDPEGKPKKTHIQDNHDGTYTVAYVPDVPGRYTILIKYGGDEIPFSPYRVR 1608
            G+G +   +T P G+  +T + +  DGTY V Y P   G  ++ + Y G  IP SP++V 
Sbjct: 247  GQGEVEAILTTPSGRKLQTLVDNMKDGTYPVLYTPMEEGPQSLDVTYKGIPIPGSPFQVN 68

Query: 1609 AVPTGDASKC 1618
            AV   DA++ 
Sbjct: 67   AVAGYDANRV 38

 Score = 52.4 bits (124), Expect(2) = 1e-14,   Method: Compositional matrix adjust.
 Identities = 29/85 (34%), Positives = 46/85 (54%), Gaps = 5/85 (5%)
 Frame = -2

Query: 1080 PCEAQLECLDNGDGTCSVSYVPTEPGDYNINILFADTHIPGSPFKAHVAPCF---DASKV 1136
            P ++++ C++  DGT +V+Y+P  PG+Y + +   D  +PGSPF A + P     D S +
Sbjct: 519  PEKSKINCVNXDDGTVNVTYIPEFPGEYKVKVSHGDKPVPGSPFTALITPSELDPDVSSI 340

Query: 1137 KCSGPGL--ERATAGEVGQFQVDCS 1159
              SG G+  E        +F VD S
Sbjct: 339  TASGYGISPEGVFIEAPSEFVVDAS 265

 Score = 47.4 bits (111), Expect(2) = 1e-14,   Method: Compositional matrix adjust.
 Identities = 22/79 (27%), Positives = 41/79 (51%)
 Frame = -1

Query: 1162 GSAELTIEICSEAGLPAEVYIQDHGDGTHTITYIPLCPGAYTVTIKYGGQPVPNFPSKLQ 1221
            G  E+   + + +G   +  + +  DGT+ + Y P+  G  ++ + Y G P+P  P ++ 
Sbjct: 247  GQGEVEAILTTPSGRKLQTLVDNMKDGTYPVLYTPMEEGPQSLDVTYKGIPIPGSPFQVN 68

Query: 1222 VEPAVDTSGVQCYGPGIEG 1240
                 D + V+ YGPG+EG
Sbjct: 67   AVAGYDANRVRAYGPGLEG 11

 Score = 54.3 bits (129), Expect(2) = 1e-13,   Method: Compositional matrix adjust.
 Identities = 29/80 (36%), Positives = 44/80 (55%)
 Frame = -1

Query: 385 GMGEVEVVIQDPTGQKGTVEPQLEARGDSTYRCSYQPTMEGVHTVHVTFAGVPIPRSPYT 444
           G GEVE ++  P+G+K  ++  ++   D TY   Y P  EG  ++ VT+ G+PIP SP+ 
Sbjct: 247 GQGEVEAILTTPSGRK--LQTLVDNMKDGTYPVLYTPMEEGPQSLDVTYKGIPIPGSPFQ 74

Query: 445 VTVGQACNPAACRAIGRGLQ 464
           V      +    RA G GL+
Sbjct: 73  VNAVAGYDANRVRAYGPGLE 14

 Score = 42.4 bits (98), Expect(2) = 1e-13,   Method: Compositional matrix adjust.
 Identities = 25/79 (31%), Positives = 39/79 (49%), Gaps = 2/79 (2%)
 Frame = -2

Query: 301 EEAKVTANNDKNRTFSVWYVPEVTGTHKVTVLFAGQHIAKSPFEVYVDKSQ--GDASKVT 358
           E++K+   N  + T +V Y+PE  G +KV V    + +  SPF   +  S+   D S +T
Sbjct: 516 EKSKINCVNXDDGTVNVTYIPEFPGEYKVKVSHGDKPVPGSPFTALITPSELDPDVSSIT 337

Query: 359 AQGPGLEPSGNIANKTTYF 377
           A G G+ P G      + F
Sbjct: 336 ASGYGISPEGVFIEAPSEF 280

 Score = 44.3 bits (103), Expect(2) = 8e-10,   Method: Compositional matrix adjust.
 Identities = 21/54 (38%), Positives = 31/54 (57%)
 Frame = -1

Query: 900 DHHDNTYTVKYIPVQQGPVGVNVTYGGDHIPKSPFSVGVSPSLDLSKIKVSGLG 953
           +  D TY V Y P+++GP  ++VTY G  IP SPF V      D ++++  G G
Sbjct: 181 NMKDGTYPVLYTPMEEGPQSLDVTYKGIPIPGSPFQVNAVAGYDANRVRAYGPG 20

 Score = 39.7 bits (91), Expect(2) = 8e-10,   Method: Compositional matrix adjust.
 Identities = 24/71 (33%), Positives = 33/71 (46%), Gaps = 3/71 (4%)
 Frame = -2

Query: 806 TFTVKYTPCGAGSYTIMVLFADQATPTSPIRVKVEPSH---DASKVKAEGPGLNRTGVEL 862
           T  V Y P   G Y + V   D+  P SP    + PS    D S + A G G++  GV +
Sbjct: 477 TVNVTYIPEFPGEYKVKVSHGDKPVPGSPFTALITPSELDPDVSSITASGYGISPEGVFI 298

Query: 863 GKPTHFTVNAK 873
             P+ F V+A 
Sbjct: 297 EAPSEFVVDAS 265

 Score = 47.0 bits (110), Expect(2) = 1e-09,   Method: Compositional matrix adjust.
 Identities = 28/81 (34%), Positives = 43/81 (53%), Gaps = 1/81 (1%)
 Frame = -1

Query: 484 GSGELKVTVKGPKGEE-RVKQKDLGDGVYGFEYYPTIPGTYTVTITWGGQNIGRSPFEVK 542
           G GE++  +  P G + +    ++ DG Y   Y P   G  ++ +T+ G  I  SPF+V 
Sbjct: 247 GQGEVEAILTTPSGRKLQTLVDNMKDGTYPVLYTPMEEGPQSLDVTYKGIPIPGSPFQVN 68

Query: 543 VGTECGNQKVRAWGPGLEGGI 563
                   +VRA+GPGLEGG+
Sbjct: 67  AVAGYDANRVRAYGPGLEGGL 5

 Score = 36.6 bits (83), Expect(2) = 1e-09,   Method: Compositional matrix adjust.
 Identities = 21/70 (30%), Positives = 37/70 (52%), Gaps = 3/70 (4%)
 Frame = -2

Query: 412 DSTYRCSYQPTMEGVHTVHVTFAGVPIPRSPYTVTVGQA-CNP--AACRAIGRGLQPKGV 468
           D T   +Y P   G + V V+    P+P SP+T  +  +  +P  ++  A G G+ P+GV
Sbjct: 483 DGTVNVTYIPEFPGEYKVKVSHGDKPVPGSPFTALITPSELDPDVSSITASGYGISPEGV 304

Query: 469 RVKETADFKV 478
            ++  ++F V
Sbjct: 303 FIEAPSEFVV 274

 Score = 63.2 bits (152), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 42/115 (36%), Positives = 53/115 (46%)
 Frame = -1

Query: 1229 SGVQCYGPGIEGQGVFREATTEFSVDARALTQTGGPHVKARVANPSGNLTDTYVQDCGDG 1288
            SG +C GP ++GQG                       V+A +  PSG    T V +  DG
Sbjct: 277  SGRECVGP-LKGQG----------------------EVEAILTTPSGRKLQTLVDNMKDG 167

Query: 1289 TYKVEYTPYEEGVHSVDVTYDGXXXXXXXXXXXXTEGCDPSRVRVHGPGIQSGTT 1343
            TY V YTP EEG  S+DVTY G              G D +RVR +GPG++ G T
Sbjct: 166  TYPVLYTPMEEGPQSLDVTYKGIPIPGSPFQVNAVAGYDANRVRAYGPGLEGGLT 2

 Score = 51.2 bits (121), Expect(2) = 4e-09,   Method: Compositional matrix adjust.
 Identities = 27/67 (40%), Positives = 40/67 (59%), Gaps = 2/67 (2%)
 Frame = -1

Query: 1080 PCEAQLECL-DN-GDGTCSVSYVPTEPGDYNINILFADTHIPGSPFKAHVAPCFDASKVK 1137
            P   +L+ L DN  DGT  V Y P E G  ++++ +    IPGSPF+ +    +DA++V+
Sbjct: 214  PSGRKLQTLVDNMKDGTYPVLYTPMEEGPQSLDVTYKGIPIPGSPFQVNAVAGYDANRVR 35

Query: 1138 CSGPGLE 1144
              GPGLE
Sbjct: 34   AYGPGLE 14

 Score = 30.0 bits (66), Expect(2) = 4e-09,   Method: Compositional matrix adjust.
 Identities = 22/67 (32%), Positives = 37/67 (55%), Gaps = 6/67 (8%)
 Frame = -2

Query: 1004 VRFVPREEGPYEVEVTYDGVPVPGSPFPLEAVAPTKP----SKVKAFGPGL--QGGNAGS 1057
            V ++P   G Y+V+V++   PVPGSPF    + P++     S + A G G+  +G    +
Sbjct: 468  VTYIPEFPGEYKVKVSHGDKPVPGSPF-TALITPSELDPDVSSITASGYGISPEGVFIEA 292

Query: 1058 PARFTID 1064
            P+ F +D
Sbjct: 291  PSEFVVD 271

 Score = 60.5 bits (145), Expect = 9e-09,   Method: Compositional matrix adjust.
 Identities = 60/194 (30%), Positives = 87/194 (44%), Gaps = 14/194 (7%)
 Frame = -1

Query: 2206 EAGAGGLAIAVEGPSKAEISFED--RKDGSCG----VAYVVQEPGD--YEVSVKFNEEHI 2257
            E   G L IAV+GP K +    +  R +G C     V++ +Q  G+   + S +    H 
Sbjct: 559  ETRVGDLDIAVDGPGKIQDKLRE*XRWNGQCDLHT*VSWGIQGEGEPRGQASTRITL-HC 383

Query: 2258 PDSPFVVPVASP------SGDARRLTVSSLQESGLKVNQPASFAVSLNGAKGAIDAKVHS 2311
            P   F    A P      S   R +T  S+    ++V         L G +G ++A + +
Sbjct: 382  PHYTF*---AGP*CQQHNSVWLRNITRGSVH*GTVRVCSGRECVGPLKG-QGEVEAILTT 215

Query: 2312 PSGALEECYVTEIDQDKYAVRFIPRENGIYLIDVKFNGTHIPGSPFKIRVGEPGHGGDPG 2371
            PSG   +  V  +    Y V + P E G   +DV + G  IPGSPF++       G D  
Sbjct: 214  PSGRKLQTLVDNMKDGTYPVLYTPMEEGPQSLDVTYKGIPIPGSPFQVNAVA---GYDAN 44

Query: 2372 LVSAYGAGLEGGVT 2385
             V AYG GLEGG+T
Sbjct: 43   RVRAYGPGLEGGLT 2

 Score = 58.9 bits (141), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 33/75 (44%), Positives = 42/75 (56%), Gaps = 3/75 (4%)
 Frame = -2

Query: 1187 DGTHTITYIPLCPGAYTVTIKYGGQPVPNFPSKLQVEPAV---DTSGVQCYGPGIEGQGV 1243
            DGT  +TYIP  PG Y V + +G +PVP  P    + P+    D S +   G GI  +GV
Sbjct: 483  DGTVNVTYIPEFPGEYKVKVSHGDKPVPGSPFTALITPSELDPDVSSITASGYGISPEGV 304

Query: 1244 FREATTEFSVDARAL 1258
            F EA +EF VDA  L
Sbjct: 303  FIEAPSEFVVDASVL 259

 Score = 57.8 bits (138), Expect = 6e-08,   Method: Compositional matrix adjust.
 Identities = 31/80 (38%), Positives = 44/80 (55%), Gaps = 1/80 (1%)
 Frame = -1

Query: 1742 KGEITGEVRMPSGKVAQPSITDNKDGTVTVRYSPSEAGLHEMDIRYDNMHIPGSPLQF-Y 1800
            +GE+   +  PSG+  Q  + + KDGT  V Y+P E G   +D+ Y  + IPGSP Q   
Sbjct: 244  QGEVEAILTTPSGRKLQTLVDNMKDGTYPVLYTPMEEGPQSLDVTYKGIPIPGSPFQVNA 65

Query: 1801 VDYVNCGHITAYGPGLTHGV 1820
            V   +   + AYGPGL  G+
Sbjct: 64   VAGYDANRVRAYGPGLEGGL 5

 Score = 57.4 bits (137), Expect = 8e-08,   Method: Compositional matrix adjust.
 Identities = 23/49 (46%), Positives = 36/49 (73%)
 Frame = -2

Query: 1846 PSKAEISCTDNQDGTCSVSYLPVLPGDYSILVKYNDQHIPGSPFTARVT 1894
            P K++I+C +  DGT +V+Y+P  PG+Y + V + D+ +PGSPFTA +T
Sbjct: 519  PEKSKINCVNXDDGTVNVTYIPEFPGEYKVKVSHGDKPVPGSPFTALIT 373

 Score = 38.5 bits (88), Expect(2) = 1e-07,   Method: Compositional matrix adjust.
 Identities = 19/62 (30%), Positives = 31/62 (50%)
 Frame = -2

Query: 1551 GLLAVQITDPEGKPKKTHIQDNHDGTYTVAYVPDVPGRYTILIKYGGDEIPFSPYRVRAV 1610
            G+    + DPE    K +  +  DGT  V Y+P+ PG Y + + +G   +P SP+     
Sbjct: 546  GIWI*LLMDPEKS--KINCVNXDDGTVNVTYIPEFPGEYKVKVSHGDKPVPGSPFTALIT 373

Query: 1611 PT 1612
            P+
Sbjct: 372  PS 367

 Score = 38.1 bits (87), Expect(2) = 1e-07,   Method: Compositional matrix adjust.
 Identities = 23/80 (28%), Positives = 34/80 (42%)
 Frame = -1

Query: 1653 GKGKVTCTVCTPDGSXXXXXXXXXXXGTFDIFYTAPQPGKYVICVRFGGEHVPNSPFQVT 1712
            G+G+V   + TP G            GT+ + YT  + G   + V + G  +P SPFQV 
Sbjct: 247  GQGEVEAILTTPSGRKLQTLVDNMKDGTYPVLYTPMEEGPQSLDVTYKGIPIPGSPFQVN 68

Query: 1713 IPERPMVGVNGLDVTSLRPF 1732
                    V G D   +R +
Sbjct: 67   -------AVAGYDANRVRAY 29

 Score = 55.8 bits (133), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 33/70 (47%), Positives = 43/70 (61%), Gaps = 2/70 (2%)
 Frame = -1

Query: 1368 PSEAKMSCM-DN-KDGSCSVEYIPYEAGTYSLNVTYGGHQVPGSPFKVPVHDVTDASKVK 1425
            PS  K+  + DN KDG+  V Y P E G  SL+VTY G  +PGSPF+V      DA++V+
Sbjct: 214  PSGRKLQTLVDNMKDGTYPVLYTPMEEGPQSLDVTYKGIPIPGSPFQVNAVAGYDANRVR 35

Query: 1426 CSGPGLSPGM 1435
              GPGL  G+
Sbjct: 34   AYGPGLEGGL 5

 Score = 54.7 bits (130), Expect = 5e-07,   Method: Compositional matrix adjust.
 Identities = 30/77 (38%), Positives = 47/77 (61%)
 Frame = -1

Query: 2114 DMTAQVTSPSGKTHEAEIVEGENHTYCIRFVPAEMGMHTVSVKYKGQHVPGSPFQFTVGP 2173
            ++ A +T+PSG+  +  +   ++ TY + + P E G  ++ V YKG  +PGSPFQ  V  
Sbjct: 238  EVEAILTTPSGRKLQTLVDNMKDGTYPVLYTPMEEGPQSLDVTYKGIPIPGSPFQ--VNA 65

Query: 2174 LGEGGAHKVRAGGPGLE 2190
            +    A++VRA GPGLE
Sbjct: 64   VAGYDANRVRAYGPGLE 14

 Score = 39.7 bits (91), Expect(2) = 5e-07,   Method: Compositional matrix adjust.
 Identities = 25/71 (35%), Positives = 41/71 (57%), Gaps = 3/71 (4%)
 Frame = -2

Query: 1945 NGHVGISFVPKETGEHLVHVKKNGQHVASSPIPVVISQSEIG-DASRVRVSGQGLH-EGH 2002
            +G V ++++P+  GE+ V V    + V  SP   +I+ SE+  D S +  SG G+  EG 
Sbjct: 483  DGTVNVTYIPEFPGEYKVKVSHGDKPVPGSPFTALITPSELDPDVSSITASGYGISPEGV 304

Query: 2003 TFE-PAEFIID 2012
              E P+EF++D
Sbjct: 303  FIEAPSEFVVD 271

 Score = 34.3 bits (77), Expect(2) = 5e-07,   Method: Compositional matrix adjust.
 Identities = 15/45 (33%), Positives = 25/45 (55%)
 Frame = -1

Query: 2030 KVDINTEDLEDGTCRVTYCPTEPGNYIINIKFADQHVPGSPFSVK 2074
            K+    ++++DGT  V Y P E G   +++ +    +PGSPF V 
Sbjct: 202  KLQTLVDNMKDGTYPVLYTPMEEGPQSLDVTYKGIPIPGSPFQVN 68

 Score = 36.6 bits (83), Expect(2) = 4e-05,   Method: Compositional matrix adjust.
 Identities = 25/70 (35%), Positives = 35/70 (50%), Gaps = 2/70 (2%)
 Frame = -1

Query: 589 PSQAKIE--CDDKGDGSCDVRYWPQEAGEYAVHVLCNSEDIRLSPFMADIREAPQDFHPD 646
           PS  K++   D+  DG+  V Y P E G  ++ V      I  SPF  +   A   +  +
Sbjct: 214 PSGRKLQTLVDNMKDGTYPVLYTPMEEGPQSLDVTYKGIPIPGSPFQVN---AVAGYDAN 44

Query: 647 RVKARGPGLE 656
           RV+A GPGLE
Sbjct: 43  RVRAYGPGLE 14

 Score = 31.2 bits (69), Expect(2) = 4e-05,   Method: Compositional matrix adjust.
 Identities = 19/80 (23%), Positives = 35/80 (43%), Gaps = 5/80 (6%)
 Frame = -2

Query: 500 RVKQKDLGDGVYGFEYYPTIPGTYTVTITWGGQNIGRSPFEV-----KVGTECGNQKVRA 554
           ++   +  DG     Y P  PG Y V ++ G + +  SPF       ++  +  +     
Sbjct: 507 KINCVNXDDGTVNVTYIPEFPGEYKVKVSHGDKPVPGSPFTALITPSELDPDVSSITASG 328

Query: 555 WGPGLEGGIVGKSADFVVEA 574
           +G   EG  +   ++FVV+A
Sbjct: 327 YGISPEGVFIEAPSEFVVDA 268

 Score = 47.4 bits (111), Expect = 8e-05,   Method: Compositional matrix adjust.
 Identities = 31/81 (38%), Positives = 43/81 (53%)
 Frame = -1

Query: 285 GQGEVLVYVEDPAGHQEEAKVTANNDKNRTFSVWYVPEVTGTHKVTVLFAGQHIAKSPFE 344
           GQGEV   +  P+G + +  V  +N K+ T+ V Y P   G   + V + G  I  SPF+
Sbjct: 247 GQGEVEAILTTPSGRKLQTLV--DNMKDGTYPVLYTPMEEGPQSLDVTYKGIPIPGSPFQ 74

Query: 345 VYVDKSQGDASKVTAQGPGLE 365
           V       DA++V A GPGLE
Sbjct: 73  VNAVAGY-DANRVRAYGPGLE 14

 Score = 47.0 bits (110), Expect = 9e-05,   Method: Compositional matrix adjust.
 Identities = 22/49 (44%), Positives = 29/49 (59%)
 Frame = -2

Query: 2028 PSKVDINTEDLEDGTCRVTYCPTEPGNYIINIKFADQHVPGSPFSVKVT 2076
            P K  IN  + +DGT  VTY P  PG Y + +   D+ VPGSPF+  +T
Sbjct: 519  PEKSKINCVNXDDGTVNVTYIPEFPGEYKVKVSHGDKPVPGSPFTALIT 373

 Score = 34.3 bits (77), Expect(2) = 1e-04,   Method: Compositional matrix adjust.
 Identities = 26/70 (37%), Positives = 37/70 (52%), Gaps = 3/70 (4%)
 Frame = -1

Query: 1835 GEGGLSLAIEGPSKAEI-SCTDN-QDGTCSVSYLPVLPGDYSILVKYNDQHIPGSPFTAR 1892
            G+G +   +  PS  ++ +  DN +DGT  V Y P+  G  S+ V Y    IPGSPF   
Sbjct: 247  GQGEVEAILTTPSGRKLQTLVDNMKDGTYPVLYTPMEEGPQSLDVTYKGIPIPGSPFQVN 68

Query: 1893 -VTGDDSMRM 1901
             V G D+ R+
Sbjct: 67   AVAGYDANRV 38

 Score = 31.6 bits (70), Expect(2) = 1e-04,   Method: Compositional matrix adjust.
 Identities = 27/87 (31%), Positives = 41/87 (47%), Gaps = 12/87 (13%)
 Frame = -2

Query: 1766 DGTVTVRYSPSEAGLHEMDIRYDNMHIPGSPLQFYVDYV----NCGHITAYGPGLT-HGV 1820
            DGTV V Y P   G +++ + + +  +PGSP    +       +   ITA G G++  GV
Sbjct: 483  DGTVNVTYIPEFPGEYKVKVSHGDKPVPGSPFTALITPSELDPDVSSITASGYGISPEGV 304

Query: 1821 -VNKPATFTVNT------KDAGEGGLS 1840
             +  P+ F V+       KD G   LS
Sbjct: 303  FIEAPSEFVVDASVLDP*KDKGRWRLS 223

 Score = 33.1 bits (74), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 32/118 (27%), Positives = 44/118 (37%), Gaps = 3/118 (2%)
 Frame = -2

Query: 2410 PSKVKMDCQECPEG-YRVTYTPMAPGSYLISIKYGGPYHIGGSPFKAKVTGPRLVSNHSL 2468
            P K K++C    +G   VTY P  PG Y + + +G    + GSPF A +T   L      
Sbjct: 519  PEKSKINCVNXDDGTVNVTYIPEFPGEYKVKVSHGD-KPVPGSPFTALITPSEL------ 361

Query: 2469 HETSSVFVDSLTKVATVPQHATSGPGPADVSKVVAKGLGLSK--AYVGQKSNFTVDCS 2524
                                        DVS + A G G+S    ++   S F VD S
Sbjct: 360  --------------------------DPDVSSITASGYGISPEGVFIEAPSEFVVDAS 265

 Score = 33.1 bits (74), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 23/74 (31%), Positives = 34/74 (45%), Gaps = 2/74 (2%)
 Frame = -2

Query: 2325 DQDKYAVRFIPRENGIYLIDVKFNGTHIPGSPFKIRVGEPGHGGDPGLVSAYGAGL--EG 2382
            D     V +IP   G Y + V      +PGSPF   +       D   ++A G G+  EG
Sbjct: 486  DDGTVNVTYIPEFPGEYKVKVSHGDKPVPGSPFTALITPSELDPDVSSITASGYGISPEG 307

Query: 2383 GVTGSPAEFIVNTS 2396
                +P+EF+V+ S
Sbjct: 306  VFIEAPSEFVVDAS 265

 Score = 32.3 bits (72), Expect = 2.8,   Method: Compositional matrix adjust.
 Identities = 19/73 (26%), Positives = 34/73 (46%), Gaps = 3/73 (4%)
 Frame = -2

Query: 701 NGTYSCSYVPRKPVKHTAMVSWGGVSIPNSPFRVNVGAGS---HPNKVKVYGPGVAKTGL 757
           +GT + +Y+P  P ++   VS G   +P SPF   +         + +   G G++  G+
Sbjct: 483 DGTVNVTYIPEFPGEYKVKVSHGDKPVPGSPFTALITPSELDPDVSSITASGYGISPEGV 304

Query: 758 KAHEPTYFTVDCT 770
               P+ F VD +
Sbjct: 303 FIEAPSEFVVDAS 265
>05081
          Length = 981

 Score = 75.1 bits (183), Expect = 3e-13,   Method: Compositional matrix adjust.
 Identities = 39/88 (44%), Positives = 54/88 (61%), Gaps = 1/88 (1%)
 Frame = -1

Query: 2497 DVSKVVAKGLGLSKAYVGQKSNFTVDCSKAGNNMLLVGVHGPR-TPCEEILVKHMGSRLY 2555
            D SKVVAKG GL KA+  +   F VD   AG  +L VG+  P   P  E+ VK   +  Y
Sbjct: 957  DASKVVAKGQGLKKAFTNRLQTFQVDVKDAGEALLQVGMIAPSGKPEAELSVKKTTNTSY 778

Query: 2556 SVSYLLKDKGEYTLVVKWGDEHIPGSPY 2583
            +++Y + + G++ L VKWGD+ IPGSP+
Sbjct: 777  TINYKVTEIGDHVLHVKWGDDDIPGSPF 694

 Score = 58.9 bits (141), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 29/89 (32%), Positives = 51/89 (57%), Gaps = 3/89 (3%)
 Frame = -1

Query: 1986 GDASRVRVSGQGLHEGHTFEPAEFIIDTRDAGYGGLSLSIEGPS---KVDINTEDLEDGT 2042
            GDAS+V   GQGL +  T     F +D +DAG   L + +  PS   + +++ +   + +
Sbjct: 960  GDASKVVAKGQGLKKAFTNRLQTFQVDVKDAGEALLQVGMIAPSGKPEAELSVKKTTNTS 781

Query: 2043 CRVTYCPTEPGNYIINIKFADQHVPGSPF 2071
              + Y  TE G++++++K+ D  +PGSPF
Sbjct: 780  YTINYKVTEIGDHVLHVKWGDDDIPGSPF 694

 Score = 58.9 bits (141), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 31/88 (35%), Positives = 47/88 (53%), Gaps = 3/88 (3%)
 Frame = -1

Query: 1805 NCGHITAYGPGLTHGVVNKPATFTVNTKDAGEGGLSLAIEGPS---KAEISCTDNQDGTC 1861
            +   + A G GL     N+  TF V+ KDAGE  L + +  PS   +AE+S     + + 
Sbjct: 957  DASKVVAKGQGLKKAFTNRLQTFQVDVKDAGEALLQVGMIAPSGKPEAELSVKKTTNTSY 778

Query: 1862 SVSYLPVLPGDYSILVKYNDQHIPGSPF 1889
            +++Y     GD+ + VK+ D  IPGSPF
Sbjct: 777  TINYKVTEIGDHVLHVKWGDDDIPGSPF 694

 Score = 56.2 bits (134), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 34/90 (37%), Positives = 50/90 (55%), Gaps = 1/90 (1%)
 Frame = -1

Query: 1517 DASKVKASGPGLNTTGVPASLPVEFTIDAKDAGEGLLAVQITDPEGKPK-KTHIQDNHDG 1575
            DASKV A G GL       +    F +D KDAGE LL V +  P GKP+ +  ++   + 
Sbjct: 957  DASKVVAKGQGLKKA--FTNRLQTFQVDVKDAGEALLQVGMIAPSGKPEAELSVKKTTNT 784

Query: 1576 TYTVAYVPDVPGRYTILIKYGGDEIPFSPY 1605
            +YT+ Y     G + + +K+G D+IP SP+
Sbjct: 783  SYTINYKVTEIGDHVLHVKWGDDDIPGSPF 694

 Score = 54.7 bits (130), Expect = 5e-07,   Method: Compositional matrix adjust.
 Identities = 34/90 (37%), Positives = 48/90 (53%), Gaps = 1/90 (1%)
 Frame = -1

Query: 1420 DASKVKCSGPGLSPGMVRANLPQSFQVDTSKAGVAPLQVKVQGPKGLVEP-VDVVDNADG 1478
            DASKV   G GL       N  Q+FQVD   AG A LQV +  P G  E  + V    + 
Sbjct: 957  DASKVVAKGQGLKKAF--TNRLQTFQVDVKDAGEALLQVGMIAPSGKPEAELSVKKTTNT 784

Query: 1479 TQTVNYVPSREGSYSISVLYGEEEVPRSPF 1508
            + T+NY  +  G + + V +G++++P SPF
Sbjct: 783  SYTINYKVTEIGDHVLHVKWGDDDIPGSPF 694

 Score = 52.4 bits (124), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 29/87 (33%), Positives = 47/87 (54%), Gaps = 1/87 (1%)
 Frame = -1

Query: 1132 DASKVKCSGPGLERATAGEVGQFQVDCSSAGSAELTIEICSEAGLP-AEVYIQDHGDGTH 1190
            DASKV   G GL++A    +  FQVD   AG A L + + + +G P AE+ ++   + ++
Sbjct: 957  DASKVVAKGQGLKKAFTNRLQTFQVDVKDAGEALLQVGMIAPSGKPEAELSVKKTTNTSY 778

Query: 1191 TITYIPLCPGAYTVTIKYGGQPVPNFP 1217
            TI Y     G + + +K+G   +P  P
Sbjct: 777  TINYKVTEIGDHVLHVKWGDDDIPGSP 697

 Score = 52.4 bits (124), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 37/117 (31%), Positives = 57/117 (48%), Gaps = 16/117 (13%)
 Frame = -1

Query: 2176 EGGAHKVRAGGPGLERAEAGVPAEFGIWTREAGAGGLAIAVEGPS---KAEISFEDRKDG 2232
             G A KV A G GL++A       F +  ++AG   L + +  PS   +AE+S +   + 
Sbjct: 963  RGDASKVVAKGQGLKKAFTNRLQTFQVDVKDAGEALLQVGMIAPSGKPEAELSVKKTTNT 784

Query: 2233 SCGVAYVVQEPGDYEVSVKFNEEHIPDSPFVV-------------PVASPSGDARRL 2276
            S  + Y V E GD+ + VK+ ++ IP SPFV+             PV  P G+ + L
Sbjct: 783  SYTINYKVTEIGDHVLHVKWGDDDIPGSPFVLST*TA*FPPETSFPVNKPCGENKLL 613

 Score = 49.7 bits (117), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 30/100 (30%), Positives = 55/100 (55%)
 Frame = -1

Query: 347 VDKSQGDASKVTAQGPGLEPSGNIANKTTYFEIFTAGAGMGEVEVVIQDPTGQKGTVEPQ 406
           + + +GDASKV A+G GL+ +    N+   F++    AG   ++V +  P+G K   E  
Sbjct: 975 IRRFRGDASKVVAKGQGLKKA--FTNRLQTFQVDVKDAGEALLQVGMIAPSG-KPEAELS 805

Query: 407 LEARGDSTYRCSYQPTMEGVHTVHVTFAGVPIPRSPYTVT 446
           ++   +++Y  +Y+ T  G H +HV +    IP SP+ ++
Sbjct: 804 VKKTTNTSYTINYKVTEIGDHVLHVKWGDDDIPGSPFVLS 685

 Score = 47.4 bits (111), Expect = 7e-05,   Method: Compositional matrix adjust.
 Identities = 32/87 (36%), Positives = 44/87 (50%), Gaps = 1/87 (1%)
 Frame = -1

Query: 647 RVKARGPGLEKTGVAVNKPAEFTVDAKHAGKAPLRVQVQDNEGC-SVEATVKDNGNGTYS 705
           +V A+G GL+K     N+   F VD K AG+A L+V +    G    E +VK   N +Y+
Sbjct: 948 KVVAKGQGLKKA--FTNRLQTFQVDVKDAGEALLQVGMIAPSGKPEAELSVKKTTNTSYT 775

Query: 706 CSYVPRKPVKHTAMVSWGGVSIPNSPF 732
            +Y   +   H   V WG   IP SPF
Sbjct: 774 INYKVTEIGDHVLHVKWGDDDIPGSPF 694

 Score = 42.0 bits (97), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 25/88 (28%), Positives = 38/88 (43%), Gaps = 3/88 (3%)
 Frame = -1

Query: 1327 DPSRVRVHGPGIQSGTTNKPNKFTXXXXXXXXXXXXXXXXXPS---EAKMSCMDNKDGSC 1383
            D S+V   G G++   TN+   F                  PS   EA++S     + S 
Sbjct: 957  DASKVVAKGQGLKKAFTNRLQTFQVDVKDAGEALLQVGMIAPSGKPEAELSVKKTTNTSY 778

Query: 1384 SVEYIPYEAGTYSLNVTYGGHQVPGSPF 1411
            ++ Y   E G + L+V +G   +PGSPF
Sbjct: 777  TINYKVTEIGDHVLHVKWGDDDIPGSPF 694

 Score = 42.0 bits (97), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 26/86 (30%), Positives = 40/86 (46%), Gaps = 3/86 (3%)
 Frame = -1

Query: 1041 SKVKAFGPGLQGGNAGSPARFTIDTKXXXXXXXXXXVEGPC---EAQLECLDNGDGTCSV 1097
            SKV A G GL+         F +D K          +  P    EA+L      + + ++
Sbjct: 951  SKVVAKGQGLKKAFTNRLQTFQVDVKDAGEALLQVGMIAPSGKPEAELSVKKTTNTSYTI 772

Query: 1098 SYVPTEPGDYNINILFADTHIPGSPF 1123
            +Y  TE GD+ +++ + D  IPGSPF
Sbjct: 771  NYKVTEIGDHVLHVKWGDDDIPGSPF 694

 Score = 38.1 bits (87), Expect = 0.050,   Method: Compositional matrix adjust.
 Identities = 29/91 (31%), Positives = 44/91 (48%)
 Frame = -1

Query: 844 DASKVKAEGPGLNRTGVELGKPTHFTVNAKTAGKGKLDVQFSGLAKGDAVRDVDIIDHHD 903
           DASKV A+G GL +      +   F V+ K AG+  L V       G    ++ +    +
Sbjct: 957 DASKVVAKGQGLKKAFTN--RLQTFQVDVKDAGEALLQVGMIA-PSGKPEAELSVKKTTN 787

Query: 904 NTYTVKYIPVQQGPVGVNVTYGGDHIPKSPF 934
            +YT+ Y   + G   ++V +G D IP SPF
Sbjct: 786 TSYTINYKVTEIGDHVLHVKWGDDDIPGSPF 694

 Score = 36.6 bits (83), Expect = 0.14,   Method: Compositional matrix adjust.
 Identities = 20/69 (28%), Positives = 36/69 (52%), Gaps = 6/69 (8%)
 Frame = -1

Query: 2105 LKIPEISIQD-----MTAQVTSPSGK-THEAEIVEGENHTYCIRFVPAEMGMHTVSVKYK 2158
            L+  ++ ++D     +   + +PSGK   E  + +  N +Y I +   E+G H + VK+ 
Sbjct: 900  LQTFQVDVKDAGEALLQVGMIAPSGKPEAELSVKKTTNTSYTINYKVTEIGDHVLHVKWG 721

Query: 2159 GQHVPGSPF 2167
               +PGSPF
Sbjct: 720  DDDIPGSPF 694

 Score = 33.9 bits (76), Expect = 0.83,   Method: Compositional matrix adjust.
 Identities = 18/64 (28%), Positives = 34/64 (53%), Gaps = 1/64 (1%)
 Frame = -1

Query: 1914 INISETDLSLLTATVVPPSGREEPCL-LKRLRNGHVGISFVPKETGEHLVHVKKNGQHVA 1972
            +++ +   +LL   ++ PSG+ E  L +K+  N    I++   E G+H++HVK     + 
Sbjct: 885  VDVKDAGEALLQVGMIAPSGKPEAELSVKKTTNTSYTINYKVTEIGDHVLHVKWGDDDIP 706

Query: 1973 SSPI 1976
             SP 
Sbjct: 705  GSPF 694

 Score = 33.1 bits (74), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 24/87 (27%), Positives = 36/87 (41%), Gaps = 2/87 (2%)
 Frame = -1

Query: 455 ACRAIGRGLQPKGVRVKETADFKVYTKGAGSGELKVTVKGPKG--EERVKQKDLGDGVYG 512
           A + + +G   K         F+V  K AG   L+V +  P G  E  +  K   +  Y 
Sbjct: 954 ASKVVAKGQGLKKAFTNRLQTFQVDVKDAGEALLQVGMIAPSGKPEAELSVKKTTNTSYT 775

Query: 513 FEYYPTIPGTYTVTITWGGQNIGRSPF 539
             Y  T  G + + + WG  +I  SPF
Sbjct: 774 INYKVTEIGDHVLHVKWGDDDIPGSPF 694

 Score = 31.6 bits (70), Expect = 4.3,   Method: Compositional matrix adjust.
 Identities = 27/92 (29%), Positives = 43/92 (46%), Gaps = 5/92 (5%)
 Frame = -1

Query: 2271 GDARRLTVSSLQESGLK---VNQPASFAVSLNGA-KGAIDAKVHSPSGALE-ECYVTEID 2325
            GDA ++        GLK    N+  +F V +  A +  +   + +PSG  E E  V +  
Sbjct: 960  GDASKVVAKG---QGLKKAFTNRLQTFQVDVKDAGEALLQVGMIAPSGKPEAELSVKKTT 790

Query: 2326 QDKYAVRFIPRENGIYLIDVKFNGTHIPGSPF 2357
               Y + +   E G +++ VK+    IPGSPF
Sbjct: 789  NTSYTINYKVTEIGDHVLHVKWGDDDIPGSPF 694
>19147
          Length = 474

 Score = 60.8 bits (146), Expect = 6e-09,   Method: Composition-based stats.
 Identities = 35/100 (35%), Positives = 56/100 (56%), Gaps = 3/100 (3%)
 Frame = +1

Query: 86  FLDRESIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWDEEEDEEAKKQTPKQRL 145
           ++  + +KLVSI ++ IVDGN+K+ LG+IWT+IL ++I        +D   ++ T K+ L
Sbjct: 49  YIASKGVKLVSIGAEEIVDGNVKMTLGMIWTIILRFAI--------QDITVEELTAKEGL 204

Query: 146 LGWIQNKLP---QLPITNFSRDWQSGRALGALVDSCAPGL 182
           L W Q K      + + NF   ++ G A  AL+    P L
Sbjct: 205 LLWCQRKTAPYKNVNVQNFHLSFKDGLAFCALIHRHRPEL 324
>19154
          Length = 512

 Score = 58.9 bits (141), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 42/129 (32%), Positives = 68/129 (52%), Gaps = 2/129 (1%)
 Frame = +2

Query: 1742 KGEITGEVRMPSGKVAQPSITDNKDGTVTVRYSPSEAGLHEMDIRYDNMHIPGSPLQFYV 1801
            K E T  +  PSG+     +T+       + Y PSE+G H + + Y+++ +PGSP   + 
Sbjct: 104  KCEQTVRIVSPSGQSVPVDVTETSTYGYNITYQPSESGQHRIFLTYNSLELPGSP---FT 274

Query: 1802 DYVNCGHI-TAYGPGLTHGVVNKPATFTVNTKDAGEGGLSLAIEGP-SKAEISCTDNQDG 1859
              ++ G +  AYG GL  G  +K A F ++ +    G  S+ ++GP S A+ S     DG
Sbjct: 275  QEISEGVLPPAYGEGLHRGEEDKAAIFYIDARGL-TGEPSVQVDGPNSIAKCSIEAQPDG 451

Query: 1860 TCSVSYLPV 1868
              SV+Y+PV
Sbjct: 452  QYSVTYIPV 478

 Score = 57.8 bits (138), Expect = 5e-08,   Method: Compositional matrix adjust.
 Identities = 46/149 (30%), Positives = 70/149 (46%), Gaps = 1/149 (0%)
 Frame = +2

Query: 2097 IGSHCDLSLKIPEISIQDMTAQVTSPSGKTHEAEIVEGENHTYCIRFVPAEMGMHTVSVK 2156
            + +  D S++       + T ++ SPSG++   ++ E   + Y I + P+E G H + + 
Sbjct: 59   LANWLDFSVETSRSGKCEQTVRIVSPSGQSVPVDVTETSTYGYNITYQPSESGQHRIFLT 238

Query: 2157 YKGQHVPGSPFQFTVGPLGEGGAHKVRAGGPGLERAEAGVPAEFGIWTREAGAGGLAIAV 2216
            Y    +PGSPF      + EG      A G GL R E    A F I  R    G  ++ V
Sbjct: 239  YNSLELPGSPF---TQEISEGVLPP--AYGEGLHRGEEDKAAIFYIDAR-GLTGEPSVQV 400

Query: 2217 EGP-SKAEISFEDRKDGSCGVAYVVQEPG 2244
            +GP S A+ S E + DG   V Y+  E G
Sbjct: 401  DGPNSIAKCSIEAQPDGQYSVTYIPVEVG 487

 Score = 56.2 bits (134), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 44/130 (33%), Positives = 63/130 (48%), Gaps = 2/130 (1%)
 Frame = +2

Query: 2308 KVHSPSGALEECYVTEIDQDKYAVRFIPRENGIYLIDVKFNGTHIPGSPFKIRVGEPGHG 2367
            ++ SPSG      VTE     Y + + P E+G + I + +N   +PGSPF   + E    
Sbjct: 122  RIVSPSGQSVPVDVTETSTYGYNITYQPSESGQHRIFLTYNSLELPGSPFTQEISE---- 289

Query: 2368 GDPGLVSAYGAGLEGGVTGSPAEFIVNTSNAGAGALSVTIDGPSKV-KMDCQECPEG-YR 2425
                L  AYG GL  G     A F ++ +    G  SV +DGP+ + K   +  P+G Y 
Sbjct: 290  --GVLPPAYGEGLHRGEEDKAAIFYID-ARGLTGEPSVQVDGPNSIAKCSIEAQPDGQYS 460

Query: 2426 VTYTPMAPGS 2435
            VTY P+  GS
Sbjct: 461  VTYIPVEVGS 490

 Score = 54.3 bits (129), Expect = 6e-07,   Method: Compositional matrix adjust.
 Identities = 47/145 (32%), Positives = 70/145 (48%), Gaps = 2/145 (1%)
 Frame = +2

Query: 963  EFTVKSKGAGGQGKVASKIVSPSGAAVPCKV-EPGLGADNSVVRFVPREEGPYEVEVTYD 1021
            +F+V++  +G + +   +IVSPSG +VP  V E      N  + + P E G + + +TY+
Sbjct: 74   DFSVETSRSG-KCEQTVRIVSPSGQSVPVDVTETSTYGYN--ITYQPSESGQHRIFLTYN 244

Query: 1022 GVPVPGSPFPLEAVAPTKPSKVKAFGPGLQGGNAGSPARFTIDTKXXXXXXXXXXVEGPC 1081
             + +PGSPF  E      P    A+G GL  G     A F ID +          V+GP 
Sbjct: 245  SLELPGSPFTQEISEGVLP---PAYGEGLHRGEEDKAAIFYIDAR-GLTGEPSVQVDGPN 412

Query: 1082 E-AQLECLDNGDGTCSVSYVPTEPG 1105
              A+       DG  SV+Y+P E G
Sbjct: 413  SIAKCSIEAQPDGQYSVTYIPVEVG 487

 Score = 53.9 bits (128), Expect = 7e-07,   Method: Compositional matrix adjust.
 Identities = 44/140 (31%), Positives = 66/140 (47%)
 Frame = +2

Query: 1444 FQVDTSKAGVAPLQVKVQGPKGLVEPVDVVDNADGTQTVNYVPSREGSYSISVLYGEEEV 1503
            F V+TS++G     V++  P G   PVDV + +     + Y PS  G + I + Y   E+
Sbjct: 77   FSVETSRSGKCEQTVRIVSPSGQSVPVDVTETSTYGYNITYQPSESGQHRIFLTYNSLEL 256

Query: 1504 PRSPFKVKVLPTHDASKVKASGPGLNTTGVPASLPVEFTIDAKDAGEGLLAVQITDPEGK 1563
            P SPF  ++    +     A G GL+  G      + F IDA+    G  +VQ+  P   
Sbjct: 257  PGSPFTQEI---SEGVLPPAYGEGLH-RGEEDKAAI-FYIDARGL-TGEPSVQVDGPNSI 418

Query: 1564 PKKTHIQDNHDGTYTVAYVP 1583
              K  I+   DG Y+V Y+P
Sbjct: 419  -AKCSIEAQPDGQYSVTYIP 475

 Score = 53.5 bits (127), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 42/145 (28%), Positives = 65/145 (44%), Gaps = 1/145 (0%)
 Frame = +2

Query: 1911 DIPINISETDLSLLTATVVPPSGREEPCLLKRLRNGHVGISFVPKETGEHLVHVKKNGQH 1970
            D  +  S +     T  +V PSG+  P  +         I++ P E+G+H + +  N   
Sbjct: 74   DFSVETSRSGKCEQTVRIVSPSGQSVPVDVTETSTYGYNITYQPSESGQHRIFLTYNSLE 253

Query: 1971 VASSPIPVVISQSEIGDASRVRVSGQGLHEGHTFEPAEFIIDTRDAGYGGLSLSIEGPSK 2030
            +  SP    IS+  +  A      G+GLH G   + A F ID R    G  S+ ++GP+ 
Sbjct: 254  LPGSPFTQEISEGVLPPA-----YGEGLHRGEEDKAAIFYIDARGLT-GEPSVQVDGPNS 415

Query: 2031 V-DINTEDLEDGTCRVTYCPTEPGN 2054
            +   + E   DG   VTY P E G+
Sbjct: 416  IAKCSIEAQPDGQYSVTYIPVEVGS 490

 Score = 48.5 bits (114), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 42/141 (29%), Positives = 64/141 (45%)
 Frame = +2

Query: 377 FEIFTAGAGMGEVEVVIQDPTGQKGTVEPQLEARGDSTYRCSYQPTMEGVHTVHVTFAGV 436
           F + T+ +G  E  V I  P+GQ   V+  +       Y  +YQP+  G H + +T+  +
Sbjct: 77  FSVETSRSGKCEQTVRIVSPSGQSVPVD--VTETSTYGYNITYQPSESGQHRIFLTYNSL 250

Query: 437 PIPRSPYTVTVGQACNPAACRAIGRGLQPKGVRVKETADFKVYTKGAGSGELKVTVKGPK 496
            +P SP+T  + +   P    A G GL  +G   K  A F +  +G  +GE  V V GP 
Sbjct: 251 ELPGSPFTQEISEGVLPP---AYGEGLH-RGEEDK-AAIFYIDARGL-TGEPSVQVDGPN 412

Query: 497 GEERVKQKDLGDGVYGFEYYP 517
              +   +   DG Y   Y P
Sbjct: 413 SIAKCSIEAQPDGQYSVTYIP 475

 Score = 43.5 bits (101), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 43/144 (29%), Positives = 64/144 (44%), Gaps = 4/144 (2%)
 Frame = +2

Query: 475 DFKVYTKGAGSGELKVTVKGPKGEER-VKQKDLGDGVYGFEYYPTIPGTYTVTITWGGQN 533
           DF V T  +G  E  V +  P G+   V   +     Y   Y P+  G + + +T+    
Sbjct: 74  DFSVETSRSGKCEQTVRIVSPSGQSVPVDVTETSTYGYNITYQPSESGQHRIFLTYNSLE 253

Query: 534 IGRSPFEVKVGTECGNQKVR--AWGPGLEGGIVGKSADFVVEAIGDDVGTLGFSVEGP-S 590
           +  SPF  ++     ++ V   A+G GL  G   K+A F ++A G   G     V+GP S
Sbjct: 254 LPGSPFTQEI-----SEGVLPPAYGEGLHRGEEDKAAIFYIDARG-LTGEPSVQVDGPNS 415

Query: 591 QAKIECDDKGDGSCDVRYWPQEAG 614
            AK   + + DG   V Y P E G
Sbjct: 416 IAKCSIEAQPDGQYSVTYIPVEVG 487

 Score = 42.7 bits (99), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 38/145 (26%), Positives = 55/145 (37%)
 Frame = +2

Query: 1250 EFSVDARALTQTGGPHVKARVANPSGNLTDTYVQDCGDGTYKVEYTPYEEGVHSVDVTYD 1309
            +FSV+    +++G      R+ +PSG      V +     Y + Y P E G H + +TY+
Sbjct: 74   DFSVET---SRSGKCEQTVRIVSPSGQSVPVDVTETSTYGYNITYQPSESGQHRIFLTYN 244

Query: 1310 GXXXXXXXXXXXXTEGCDPSRVRVHGPGIQSGTTNKPNKFTXXXXXXXXXXXXXXXXXPS 1369
                         +EG  P     +G G+  G  +K   F                   S
Sbjct: 245  SLELPGSPFTQEISEGVLPP---AYGEGLHRGEEDKAAIFYIDARGLTGEPSVQVDGPNS 415

Query: 1370 EAKMSCMDNKDGSCSVEYIPYEAGT 1394
             AK S     DG  SV YIP E G+
Sbjct: 416  IAKCSIEAQPDGQYSVTYIPVEVGS 490

 Score = 39.7 bits (91), Expect = 0.017,   Method: Compositional matrix adjust.
 Identities = 26/106 (24%), Positives = 52/106 (49%)
 Frame = +2

Query: 1096 SVSYVPTEPGDYNINILFADTHIPGSPFKAHVAPCFDASKVKCSGPGLERATAGEVGQFQ 1155
            +++Y P+E G + I + +    +PGSPF   ++   +       G GL R    +   F 
Sbjct: 188  NITYQPSESGQHRIFLTYNSLELPGSPFTQEIS---EGVLPPAYGEGLHRGEEDKAAIFY 358

Query: 1156 VDCSSAGSAELTIEICSEAGLPAEVYIQDHGDGTHTITYIPLCPGA 1201
            +D     + E ++++     + A+  I+   DG +++TYIP+  G+
Sbjct: 359  IDARGL-TGEPSVQVDGPNSI-AKCSIEAQPDGQYSVTYIPVEVGS 490

 Score = 37.7 bits (86), Expect = 0.063,   Method: Compositional matrix adjust.
 Identities = 16/67 (23%), Positives = 33/67 (49%)
 Frame = +2

Query: 1539 VEFTIDAKDAGEGLLAVQITDPEGKPKKTHIQDNHDGTYTVAYVPDVPGRYTILIKYGGD 1598
            ++F+++   +G+    V+I  P G+     + +     Y + Y P   G++ I + Y   
Sbjct: 71   LDFSVETSRSGKCEQTVRIVSPSGQSVPVDVTETSTYGYNITYQPSESGQHRIFLTYNSL 250

Query: 1599 EIPFSPY 1605
            E+P SP+
Sbjct: 251  ELPGSPF 271

 Score = 37.0 bits (84), Expect = 0.093,   Method: Compositional matrix adjust.
 Identities = 20/70 (28%), Positives = 35/70 (50%), Gaps = 2/70 (2%)
 Frame = +2

Query: 1827 FTVNTKDAGEGGLSLAIEGPS--KAEISCTDNQDGTCSVSYLPVLPGDYSILVKYNDQHI 1884
            F+V T  +G+   ++ I  PS     +  T+      +++Y P   G + I + YN   +
Sbjct: 77   FSVETSRSGKCEQTVRIVSPSGQSVPVDVTETSTYGYNITYQPSESGQHRIFLTYNSLEL 256

Query: 1885 PGSPFTARVT 1894
            PGSPFT  ++
Sbjct: 257  PGSPFTQEIS 286

 Score = 36.6 bits (83), Expect = 0.12,   Method: Compositional matrix adjust.
 Identities = 29/108 (26%), Positives = 49/108 (45%)
 Frame = +2

Query: 1384 SVEYIPYEAGTYSLNVTYGGHQVPGSPFKVPVHDVTDASKVKCSGPGLSPGMVRANLPQS 1443
            ++ Y P E+G + + +TY   ++PGSPF     ++++       G GL  G    +    
Sbjct: 188  NITYQPSESGQHRIFLTYNSLELPGSPF---TQEISEGVLPPAYGEGLHRG--EEDKAAI 352

Query: 1444 FQVDTSKAGVAPLQVKVQGPKGLVEPVDVVDNADGTQTVNYVPSREGS 1491
            F +D       P  V+V GP  + +   +    DG  +V Y+P   GS
Sbjct: 353  FYIDARGLTGEP-SVQVDGPNSIAK-CSIEAQPDGQYSVTYIPVEVGS 490

 Score = 35.8 bits (81), Expect = 0.21,   Method: Compositional matrix adjust.
 Identities = 19/74 (25%), Positives = 36/74 (48%)
 Frame = +2

Query: 270 MVKKRAEFTVETRSAGQGEVLVYVEDPAGHQEEAKVTANNDKNRTFSVWYVPEVTGTHKV 329
           M+    +F+VET  +G+ E  V +  P+G      VT  +     +++ Y P  +G H++
Sbjct: 56  MLANWLDFSVETSRSGKCEQTVRIVSPSGQSVPVDVTETSTYG--YNITYQPSESGQHRI 229

Query: 330 TVLFAGQHIAKSPF 343
            + +    +  SPF
Sbjct: 230 FLTYNSLELPGSPF 271

 Score = 33.5 bits (75), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 24/72 (33%), Positives = 35/72 (48%), Gaps = 3/72 (4%)
 Frame = +2

Query: 2390 EFIVNTSNAGAGALSVTIDGPS--KVKMDCQECPE-GYRVTYTPMAPGSYLISIKYGGPY 2446
            +F V TS +G    +V I  PS   V +D  E    GY +TY P   G + I + Y    
Sbjct: 74   DFSVETSRSGKCEQTVRIVSPSGQSVPVDVTETSTYGYNITYQPSESGQHRIFLTYNS-L 250

Query: 2447 HIGGSPFKAKVT 2458
             + GSPF  +++
Sbjct: 251  ELPGSPFTQEIS 286

 Score = 33.1 bits (74), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 19/71 (26%), Positives = 37/71 (52%), Gaps = 2/71 (2%)
 Frame = +2

Query: 2008 EFIIDTRDAGYGGLSLSIEGPSKVDINTEDLEDGTC--RVTYCPTEPGNYIINIKFADQH 2065
            +F ++T  +G    ++ I  PS   +  +  E  T    +TY P+E G + I + +    
Sbjct: 74   DFSVETSRSGKCEQTVRIVSPSGQSVPVDVTETSTYGYNITYQPSESGQHRIFLTYNSLE 253

Query: 2066 VPGSPFSVKVT 2076
            +PGSPF+ +++
Sbjct: 254  LPGSPFTQEIS 286
>09100
          Length = 930

 Score = 57.4 bits (137), Expect = 8e-08,   Method: Composition-based stats.
 Identities = 36/116 (31%), Positives = 62/116 (53%), Gaps = 4/116 (3%)
 Frame = +1

Query: 10  EDAPWKKIQQ--NTFTRWCNEHLKCV--SKRIANLQTDLSDGLRLIALLEVLSQKKMHRK 65
           E   W + QQ  + +  W N  LK    +  I +L+ D+ DG+    ++ ++S++++   
Sbjct: 433 ESRTWIEPQQQLSAYMAWINSQLKKKPGAHLIEDLRHDMRDGVVFADVIHIVSKQQIPGI 612

Query: 66  HNQRPTFRQMQLENVSVALEFLDRESIKLVSIDSKAIVDGNLKLILGLIWTLILHY 121
            N   T  +M+ +NV   L F+ +  IK+  I S+ IV+GNLK ++ LI  L  HY
Sbjct: 613 QNVPTTLDEMR-QNVDRVLHFMTQNRIKMHRISSRDIVEGNLKAVMRLILALAAHY 777
>29755
          Length = 460

 Score = 55.8 bits (133), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 22/45 (48%), Positives = 36/45 (80%)
 Frame = +3

Query: 2543 EEILVKHMGSRLYSVSYLLKDKGEYTLVVKWGDEHIPGSPYRIMV 2587
            +E+ VK++GS  Y+++Y +K +G Y L+V+WGDE+IPGSP+ + V
Sbjct: 3    DELTVKYVGSGQYNINYTVKQQGSYMLIVRWGDENIPGSPFAVDV 137

 Score = 40.8 bits (94), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 16/35 (45%), Positives = 24/35 (68%)
 Frame = +3

Query: 1679 GTFDIFYTAPQPGKYVICVRFGGEHVPNSPFQVTI 1713
            G ++I YT  Q G Y++ VR+G E++P SPF V +
Sbjct: 33   GQYNINYTVKQQGSYMLIVRWGDENIPGSPFAVDV 137

 Score = 38.5 bits (88), Expect = 0.037,   Method: Compositional matrix adjust.
 Identities = 18/44 (40%), Positives = 27/44 (61%)
 Frame = +3

Query: 693 EATVKDNGNGTYSCSYVPRKPVKHTAMVSWGGVSIPNSPFRVNV 736
           E TVK  G+G Y+ +Y  ++   +  +V WG  +IP SPF V+V
Sbjct: 6   ELTVKYVGSGQYNINYTVKQQGSYMLIVRWGDENIPGSPFAVDV 137

 Score = 37.0 bits (84), Expect = 0.10,   Method: Compositional matrix adjust.
 Identities = 15/36 (41%), Positives = 23/36 (63%)
 Frame = +3

Query: 1478 GTQTVNYVPSREGSYSISVLYGEEEVPRSPFKVKVL 1513
            G   +NY   ++GSY + V +G+E +P SPF V V+
Sbjct: 33   GQYNINYTVKQQGSYMLIVRWGDENIPGSPFAVDVI 140

 Score = 35.8 bits (81), Expect = 0.21,   Method: Compositional matrix adjust.
 Identities = 12/35 (34%), Positives = 24/35 (68%)
 Frame = +3

Query: 2041 GTCRVTYCPTEPGNYIINIKFADQHVPGSPFSVKV 2075
            G   + Y   + G+Y++ +++ D+++PGSPF+V V
Sbjct: 33   GQYNINYTVKQQGSYMLIVRWGDENIPGSPFAVDV 137

 Score = 33.5 bits (75), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 15/44 (34%), Positives = 26/44 (59%)
 Frame = +3

Query: 2223 EISFEDRKDGSCGVAYVVQEPGDYEVSVKFNEEHIPDSPFVVPV 2266
            E++ +    G   + Y V++ G Y + V++ +E+IP SPF V V
Sbjct: 6    ELTVKYVGSGQYNINYTVKQQGSYMLIVRWGDENIPGSPFAVDV 137

 Score = 33.5 bits (75), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 14/38 (36%), Positives = 23/38 (60%)
 Frame = +3

Query: 1859 GTCSVSYLPVLPGDYSILVKYNDQHIPGSPFTARVTGD 1896
            G  +++Y     G Y ++V++ D++IPGSPF   V  D
Sbjct: 33   GQYNINYTVKQQGSYMLIVRWGDENIPGSPFAVDVI*D 146

 Score = 32.7 bits (73), Expect = 1.7,   Method: Compositional matrix adjust.
 Identities = 15/49 (30%), Positives = 26/49 (53%)
 Frame = +3

Query: 1091 GDGTCSVSYVPTEPGDYNINILFADTHIPGSPFKAHVAPCFDASKVKCS 1139
            G G  +++Y   + G Y + + + D +IPGSPF   V   F A+ +  +
Sbjct: 27   GSGQYNINYTVKQQGSYMLIVRWGDENIPGSPFAVDVI*DFPAAHLDLT 173

 Score = 32.7 bits (73), Expect = 2.0,   Method: Compositional matrix adjust.
 Identities = 13/45 (28%), Positives = 26/45 (57%)
 Frame = +3

Query: 2317 EECYVTEIDQDKYAVRFIPRENGIYLIDVKFNGTHIPGSPFKIRV 2361
            +E  V  +   +Y + +  ++ G Y++ V++   +IPGSPF + V
Sbjct: 3    DELTVKYVGSGQYNINYTVKQQGSYMLIVRWGDENIPGSPFAVDV 137

 Score = 32.3 bits (72), Expect = 2.4,   Method: Compositional matrix adjust.
 Identities = 16/40 (40%), Positives = 21/40 (52%)
 Frame = +3

Query: 504 KDLGDGVYGFEYYPTIPGTYTVTITWGGQNIGRSPFEVKV 543
           K +G G Y   Y     G+Y + + WG +NI  SPF V V
Sbjct: 18  KYVGSGQYNINYTVKQQGSYMLIVRWGDENIPGSPFAVDV 137

 Score = 32.0 bits (71), Expect = 3.0,   Method: Compositional matrix adjust.
 Identities = 14/35 (40%), Positives = 20/35 (57%)
 Frame = +3

Query: 1381 GSCSVEYIPYEAGTYSLNVTYGGHQVPGSPFKVPV 1415
            G  ++ Y   + G+Y L V +G   +PGSPF V V
Sbjct: 33   GQYNINYTVKQQGSYMLIVRWGDENIPGSPFAVDV 137

 Score = 31.2 bits (69), Expect = 5.1,   Method: Compositional matrix adjust.
 Identities = 18/50 (36%), Positives = 27/50 (54%), Gaps = 5/50 (10%)
 Frame = +3

Query: 906 YTVKYIPVQQGPVGVNVTYGGDHIPKSPFSVGV-----SPSLDLSKIKVS 950
           Y + Y   QQG   + V +G ++IP SPF+V V     +  LDL+   V+
Sbjct: 39  YNINYTVKQQGSYMLIVRWGDENIPGSPFAVDVI*DFPAAHLDLTNSSVA 188
>35059
          Length = 669

 Score = 54.7 bits (130), Expect = 5e-07,   Method: Compositional matrix adjust.
 Identities = 41/164 (25%), Positives = 74/164 (45%), Gaps = 2/164 (1%)
 Frame = +2

Query: 2007 AEFIIDTRDAGYGGLSLSIEGPS-KVDINTEDLEDGTCRVTYCPTEPGNYIINIKFADQH 2065
            AEF++D R AG G + + ++G    + ++   ++    R TY P  PG +++ + +++  
Sbjct: 137  AEFVVDGRRAGPGEVRVELKGVRISLPVHITPIKYDRYRCTYTPAFPGGFLLYVYWSNIL 316

Query: 2066 VPGSPFSVKVTGEGRVKE-SITRRRRAPSVANIGSHCDLSLKIPEISIQDMTAQVTSPSG 2124
            VPG P  V VT +G V    +T       +A  GS   + +       +   + +     
Sbjct: 317  VPGCPHKVTVTSKGDVSXVKVTGEGLKGGIA--GSELRVFVDNKRGWSRGGNSDMFDTPT 490

Query: 2125 KTHEAEIVEGENHTYCIRFVPAEMGMHTVSVKYKGQHVPGSPFQ 2168
            +       E  +  + +   P     H + V+Y GQHVPGSP +
Sbjct: 491  RGTSGREAERLSPLHAVYPCPTSADKHLLQVRYDGQHVPGSPLR 622

 Score = 51.6 bits (122), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 38/138 (27%), Positives = 63/138 (45%), Gaps = 3/138 (2%)
 Frame = +2

Query: 2320 YVTEIDQDKYAVRFIPRENGIYLIDVKFNGTHIPGSPFKIRVGEPGHGGDPGLVSAYGAG 2379
            ++T I  D+Y   + P   G +L+ V ++   +PG P K+ V      GD   V   G G
Sbjct: 221  HITPIKYDRYRCTYTPAFPGGFLLYVYWSNILVPGCPHKVTVTSK---GDVSXVKVTGEG 391

Query: 2380 LEGGVTGSPAE-FIVNTSNAGAGALSVTIDGPSK--VKMDCQECPEGYRVTYTPMAPGSY 2436
            L+GG+ GS    F+ N      G  S   D P++     + +     + V   P +   +
Sbjct: 392  LKGGIAGSELRVFVDNKRGWSRGGNSDMFDTPTRGTSGREAERLSPLHAVYPCPTSADKH 571

Query: 2437 LISIKYGGPYHIGGSPFK 2454
            L+ ++Y G  H+ GSP +
Sbjct: 572  LLQVRYDG-QHVPGSPLR 622

 Score = 47.4 bits (111), Expect = 8e-05,   Method: Compositional matrix adjust.
 Identities = 35/123 (28%), Positives = 56/123 (45%), Gaps = 2/123 (1%)
 Frame = +2

Query: 1951 SFVPKETGEHLVHVKKNGQHVASSPIPVVISQSEIGDASRVRVSGQGLHEGHT-FEPAEF 2009
            ++ P   G  L++V  +   V   P  V ++    GD S V+V+G+GL  G    E   F
Sbjct: 257  TYTPAFPGGFLLYVYWSNILVPGCPHKVTVTSK--GDVSXVKVTGEGLKGGIAGSELRVF 430

Query: 2010 IIDTRDAGYGGLSLSIEGPSKVDINTEDLEDGTCRVTY-CPTEPGNYIINIKFADQHVPG 2068
            + + R    GG S   + P++     E          Y CPT    +++ +++  QHVPG
Sbjct: 431  VDNKRGWSRGGNSDMFDTPTRGTSGREAERLSPLHAVYPCPTSADKHLLQVRYDGQHVPG 610

Query: 2069 SPF 2071
            SP 
Sbjct: 611  SPL 619

 Score = 44.7 bits (104), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 30/100 (30%), Positives = 45/100 (45%)
 Frame = +2

Query: 666 AEFTVDAKHAGKAPLRVQVQDNEGCSVEATVKDNGNGTYSCSYVPRKPVKHTAMVSWGGV 725
           AEF VD + AG   +RV+++     S+   +       Y C+Y P  P      V W  +
Sbjct: 137 AEFVVDGRRAGPGEVRVELKGVR-ISLPVHITPIKYDRYRCTYTPAFPGGFLLYVYWSNI 313

Query: 726 SIPNSPFRVNVGAGSHPNKVKVYGPGVAKTGLKAHEPTYF 765
            +P  P +V V +    + VKV G G+ K G+   E   F
Sbjct: 314 LVPGCPHKVTVTSKGDVSXVKVTGEGL-KGGIAGSELRVF 430

 Score = 44.7 bits (104), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 45/168 (26%), Positives = 69/168 (41%), Gaps = 6/168 (3%)
 Frame = +2

Query: 963  EFTVKSKGAG-GQGKVASKIVSPSGAAVPCKVEPGLGADNSVVRFVPREEGPYEVEVTYD 1021
            EF V  + AG G+ +V  K V  S   +P  + P +  D     + P   G + + V + 
Sbjct: 140  EFVVDGRRAGPGEVRVELKGVRIS---LPVHITP-IKYDRYRCTYTPAFPGGFLLYVYWS 307

Query: 1022 GVPVPGSPFPLEAVAPTKPSKVKAFGPGLQGGNAGSPARFTIDTKXXXXXXXXXXV---- 1077
             + VPG P  +   +    S VK  G GL+GG AGS  R  +D K          +    
Sbjct: 308  NILVPGCPHKVTVTSKGDVSXVKVTGEGLKGGIAGSELRVFVDNKRGWSRGGNSDMFDTP 487

Query: 1078 -EGPCEAQLECLDNGDGTCSVSYVPTEPGDYNINILFADTHIPGSPFK 1124
              G    + E L       +V   PT    + + + +   H+PGSP +
Sbjct: 488  TRGTSGREAERLSP---LHAVYPCPTSADKHLLQVRYDGQHVPGSPLR 622

 Score = 42.7 bits (99), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 44/177 (24%), Positives = 75/177 (42%), Gaps = 6/177 (3%)
 Frame = +2

Query: 370 IANKTTYFEIFTAG--AGMGEVEVVIQDPTGQKGTVEPQLEARGDSTYRCSYQPTMEGVH 427
           IA  T   E    G  AG GEV V ++   G + ++   +       YRC+Y P   G  
Sbjct: 116 IARATVQAEFVVDGRRAGPGEVRVELK---GVRISLPVHITPIKYDRYRCTYTPAFPGGF 286

Query: 428 TVHVTFAGVPIPRSPYTVTVGQACNPAACRAIGRGLQPKGVRVKETADF----KVYTKGA 483
            ++V ++ + +P  P+ VTV    + +  +  G GL+  G+   E   F    + +++G 
Sbjct: 287 LLYVYWSNILVPGCPHKVTVTSKGDVSXVKVTGEGLK-GGIAGSELRVFVDNKRGWSRGG 463

Query: 484 GSGELKVTVKGPKGEERVKQKDLGDGVYGFEYYPTIPGTYTVTITWGGQNIGRSPFE 540
            S       +G  G E  +   L   VY     PT    + + + + GQ++  SP  
Sbjct: 464 NSDMFDTPTRGTSGREAERLSPL-HAVYPC---PTSADKHLLQVRYDGQHVPGSPLR 622

 Score = 42.7 bits (99), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 53/204 (25%), Positives = 76/204 (37%), Gaps = 8/204 (3%)
 Frame = +2

Query: 2389 AEFIVNTSNAGAGALSVTIDGPSKVKMDCQECP---EGYRVTYTPMAPGSYLISIKYGGP 2445
            AEF+V+   AG G + V + G  ++ +     P   + YR TYTP  PG +L+ + Y   
Sbjct: 137  AEFVVDGRRAGPGEVRVELKG-VRISLPVHITPIKYDRYRCTYTPAFPGGFLLYV-YWSN 310

Query: 2446 YHIGGSPFKAKVTGPRLVSNHSLHETSSVFVDSLTKVATVPQHATSGPGPADVSKVVAKG 2505
              + G P K  VT                                      DVS V   G
Sbjct: 311  ILVPGCPHKVTVTSK-----------------------------------GDVSXVKVTG 385

Query: 2506 LGLSKAYVGQKSNFTVD----CSKAGN-NMLLVGVHGPRTPCEEILVKHMGSRLYSVSYL 2560
             GL     G +    VD     S+ GN +M      G      E L     S L++V   
Sbjct: 386  EGLKGGIAGSELRVFVDNKRGWSRGGNSDMFDTPTRGTSGREAERL-----SPLHAVYPC 550

Query: 2561 LKDKGEYTLVVKWGDEHIPGSPYR 2584
                 ++ L V++  +H+PGSP R
Sbjct: 551  PTSADKHLLQVRYDGQHVPGSPLR 622

 Score = 41.6 bits (96), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 50/186 (26%), Positives = 74/186 (39%), Gaps = 1/186 (0%)
 Frame = +2

Query: 274 RAEFTVETRSAGQGEVLVYVEDPAGHQEEAKVTANNDKNRTFSVWYVPEVTGTHKVTVLF 333
           +AEF V+ R AG GEV V ++   G +    V     K   +   Y P   G   + V +
Sbjct: 134 QAEFVVDGRRAGPGEVRVELK---GVRISLPVHITPIKYDRYRCTYTPAFPGGFLLYVYW 304

Query: 334 AGQHIAKSPFEVYVDKSQGDASKVTAQGPGLEPSGNIANKTTYFEIFTAGAGMGEVEVVI 393
           +   +   P +V V  S+GD S V   G GL+  G   ++   F     G   G    + 
Sbjct: 305 SNILVPGCPHKVTV-TSKGDVSXVKVTGEGLK-GGIAGSELRVFVDNKRGWSRGGNSDMF 478

Query: 394 QDPTGQKGTVEPQLEARGDSTYRCSYQPTMEGVHTVHVTFAGVPIPRSPYTVTVGQACN- 452
             PT      E +  +   + Y C   PT    H + V + G  +P SP      ++   
Sbjct: 479 DTPTRGTSGREAERLSPLHAVYPC---PTSADKHLLQVRYDGQHVPGSPLRP*ESESLQM 649

Query: 453 PAACRA 458
           PA CR 
Sbjct: 650 PARCRC 667

 Score = 40.8 bits (94), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 29/122 (23%), Positives = 49/122 (40%)
 Frame = +2

Query: 1098 SYVPTEPGDYNINILFADTHIPGSPFKAHVAPCFDASKVKCSGPGLERATAGEVGQFQVD 1157
            +Y P  PG + + + +++  +PG P K  V    D S VK +G GL+   AG   +  VD
Sbjct: 257  TYTPAFPGGFLLYVYWSNILVPGCPHKVTVTSKGDVSXVKVTGEGLKGGIAGSELRVFVD 436

Query: 1158 CSSAGSAELTIEICSEAGLPAEVYIQDHGDGTHTITYIPLCPGAYTVTIKYGGQPVPNFP 1217
                 S     ++             +     H +   P     + + ++Y GQ VP  P
Sbjct: 437  NKRGWSRGGNSDMFDTPTRGTSGREAERLSPLHAVYPCPTSADKHLLQVRYDGQHVPGSP 616

Query: 1218 SK 1219
             +
Sbjct: 617  LR 622

 Score = 40.4 bits (93), Expect = 0.011,   Method: Compositional matrix adjust.
 Identities = 31/100 (31%), Positives = 45/100 (45%), Gaps = 1/100 (1%)
 Frame = +2

Query: 1142 GLERATAGEVGQFQVDCSSAGSAELTIEICS-EAGLPAEVYIQDHGDGTHTITYIPLCPG 1200
            G E A A    +F VD   AG  E+ +E+      LP  V+I       +  TY P  PG
Sbjct: 107  GAEIARATVQAEFVVDGRRAGPGEVRVELKGVRISLP--VHITPIKYDRYRCTYTPAFPG 280

Query: 1201 AYTVTIKYGGQPVPNFPSKLQVEPAVDTSGVQCYGPGIEG 1240
             + + + +    VP  P K+ V    D S V+  G G++G
Sbjct: 281  GFLLYVYWSNILVPGCPHKVTVTSKGDVSXVKVTGEGLKG 400

 Score = 37.7 bits (86), Expect = 0.069,   Method: Compositional matrix adjust.
 Identities = 42/166 (25%), Positives = 72/166 (43%), Gaps = 14/166 (8%)
 Frame = +2

Query: 1825 ATFTVNTKDAGEGGLSLAIEGPS-KAEISCTDNQDGTCSVSYLPVLPGDYSILVKYNDQH 1883
            A F V+ + AG G + + ++G      +  T  +      +Y P  PG + + V +++  
Sbjct: 137  AEFVVDGRRAGPGEVRVELKGVRISLPVHITPIKYDRYRCTYTPAFPGGFLLYVYWSNIL 316

Query: 1884 IPGSPFTARVT--GDDS---MRMSHLKVGSA-ADIPINISET-------DLSLLTATVVP 1930
            +PG P    VT  GD S   +    LK G A +++ + +          +  +       
Sbjct: 317  VPGCPHKVTVTSKGDVSXVKVTGEGLKGGIAGSELRVFVDNKRGWSRGGNSDMFDTPTRG 496

Query: 1931 PSGREEPCLLKRLRNGHVGISFVPKETGEHLVHVKKNGQHVASSPI 1976
             SGRE     +RL   H  +   P    +HL+ V+ +GQHV  SP+
Sbjct: 497  TSGREA----ERLSPLHA-VYPCPTSADKHLLQVRYDGQHVPGSPL 619

 Score = 33.9 bits (76), Expect = 0.90,   Method: Compositional matrix adjust.
 Identities = 12/24 (50%), Positives = 17/24 (70%)
 Frame = +2

Query: 1775 PSEAGLHEMDIRYDNMHIPGSPLQ 1798
            P+ A  H + +RYD  H+PGSPL+
Sbjct: 551  PTSADKHLLQVRYDGQHVPGSPLR 622

 Score = 33.9 bits (76), Expect = 0.96,   Method: Compositional matrix adjust.
 Identities = 21/54 (38%), Positives = 26/54 (48%)
 Frame = +2

Query: 1387 YIPYEAGTYSLNVTYGGHQVPGSPFKVPVHDVTDASKVKCSGPGLSPGMVRANL 1440
            Y P   G + L V +    VPG P KV V    D S VK +G GL  G+  + L
Sbjct: 260  YTPAFPGGFLLYVYWSNILVPGCPHKVTVTSKGDVSXVKVTGEGLKGGIAGSEL 421

 Score = 31.2 bits (69), Expect = 6.3,   Method: Compositional matrix adjust.
 Identities = 22/84 (26%), Positives = 40/84 (47%)
 Frame = +2

Query: 2504 KGLGLSKAYVGQKSNFTVDCSKAGNNMLLVGVHGPRTPCEEILVKHMGSRLYSVSYLLKD 2563
            KG  +++A V  ++ F VD  +AG   + V + G R     + +  +    Y  +Y    
Sbjct: 104  KGAEIARATV--QAEFVVDGRRAGPGEVRVELKGVRISLP-VHITPIKYDRYRCTYTPAF 274

Query: 2564 KGEYTLVVKWGDEHIPGSPYRIMV 2587
             G + L V W +  +PG P+++ V
Sbjct: 275  PGGFLLYVYWSNILVPGCPHKVTV 346
>09711
          Length = 3041

 Score = 54.3 bits (129), Expect = 7e-07,   Method: Compositional matrix adjust.
 Identities = 58/219 (26%), Positives = 103/219 (47%), Gaps = 14/219 (6%)
 Frame = +1

Query: 18   QQNTFTRWCNEHLKCVSKRIANLQTDLSDGLRLIALLEV----LSQKKMHRKHNQRPTFR 73
            ++ T+  W N     VS  + +L +DL DGL +  L +     L      +K   +   R
Sbjct: 850  EEKTYRNWMNS--LGVSPFVHHLYSDLYDGLIIFQLYDYIQPGLVDWSKVKKKFNKLKAR 1023

Query: 74   QMQLENVSVALEF---LDRESIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWDE 130
              ++EN + A+E    +    +KLV I  + I+DGN  L LGL+W L+  Y++++     
Sbjct: 1024 FERIENCNYAVELGPQVKLVKVKLVGIAGQDILDGNPVLTLGLVWQLMRAYTLAIL---- 1191

Query: 131  EEDEEAKKQTPKQRLLGWIQNKLPQLP-ITNFS-RDWQSGRALGALVDSCAPGLCPDWDS 188
             +  E  K      ++ W+ +K+ +   I+ F  R    G  +  ++++  PG+  +WD+
Sbjct: 1192 SKITENNKPISDNEIITWVNSKIKKDDRISGFQDRKLNDGVIVARVIEAIKPGIV-NWDN 1368

Query: 189  WDAS-----KPVNNAREAMQQADDWLGIPQVITPEEIVD 222
             D S       + NAR A+  A   +G      PE+IV+
Sbjct: 1369 IDCSARDYQDRLTNARYAIGLARK-IGAGVYALPEDIVE 1482

 Score = 41.6 bits (96), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 47/190 (24%), Positives = 79/190 (41%), Gaps = 27/190 (14%)
 Frame = +1

Query: 18  QQNTFTRWCNEHLK----CVSKRIANLQTD-------LSDGLRLIALL-EVLSQKKMHRK 65
           +Q  F  W N HL     C  K +  L  D       ++DG+ L  L+   +S     R 
Sbjct: 52  EQKAFAEWINRHLSDXPDC--KHLLPLDADGTQLFGQMADGVLLCKLINHSVSNTIDERT 225

Query: 66  HNQRPTFRQMQLENVSVALEFLDRESIKLVSIDSKAIVDGNLKLILGLIWTLI---LHYS 122
            N++      + EN+++A+          V+I  + +  G   L+LGL+W +I   L   
Sbjct: 226 INKQNLSLYRRHENLTLAVNSAGAIGCTTVNIGPEDLAAGRPHLVLGLLWQIIRIGLLSD 405

Query: 123 ISMP--------MWDEEEDEEAKKQTPKQRLLGWIQNKLPQL----PITNFSRDWQSGRA 170
           I++         + D E  E+  + +P+Q LL W+   L +      I NF  D +   A
Sbjct: 406 INLAHHPGLVNLLLDGETIEDLIRLSPEQILLRWVNYHLNRAGCDRQIXNFGEDIKDSEA 585

Query: 171 LGALVDSCAP 180
              L+   +P
Sbjct: 586 YTHLLKQISP 615
>17613
          Length = 1108

 Score = 53.9 bits (128), Expect = 7e-07,   Method: Composition-based stats.
 Identities = 27/63 (42%), Positives = 41/63 (65%)
 Frame = +2

Query: 90  ESIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWDEEEDEEAKKQTPKQRLLGWI 149
           + +KLVSI ++ IVDGN+K+ LG+IWT+IL ++I        +D   ++ T K+ LL W 
Sbjct: 59  KGVKLVSIGAEEIVDGNVKMTLGMIWTIILRFAI--------QDITVEELTAKEGLLLWC 214

Query: 150 QNK 152
           Q K
Sbjct: 215 QRK 223
>04951
          Length = 2852

 Score = 41.6 bits (96), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 43/157 (27%), Positives = 78/157 (49%), Gaps = 10/157 (6%)
 Frame = +1

Query: 76  QLENVSVALEF---LDRESIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWDEEE 132
           ++EN   A++    +    +KLV I  K I DGN  L LGL+W L+  Y++++      +
Sbjct: 4   KIENCEYAVQLGPQMKVCKMKLVGIGGKDIHDGNPVLTLGLVWQLMRAYTLAIL----SK 171

Query: 133 DEEAKKQTPKQRLLGWIQNKLPQLPITNFSRD--WQSGRALGALVDSCAPGLCPDWDSW- 189
             E KK      ++ W+ +K+ +       +D     G  +  +++S  PG+  +W++  
Sbjct: 172 LTEDKKPIQDSEIVDWVNSKVKKDERIGSFQDSKLNDGVIVAKVIESIKPGIV-NWENIN 348

Query: 190 -DASKP---VNNAREAMQQADDWLGIPQVITPEEIVD 222
            +AS+P   + NAR A+  A   +G      PE+IV+
Sbjct: 349 PNASEPDDRLANARYAIGLARK-IGAGVYALPEDIVE 456
>18202
          Length = 424

 Score = 40.0 bits (92), Expect = 0.012,   Method: Composition-based stats.
 Identities = 34/132 (25%), Positives = 64/132 (48%)
 Frame = -1

Query: 22  FTRWCNEHLKCVSKRIANLQTDLSDGLRLIALLEVLSQKKMHRKHNQRPTFRQMQLENVS 81
           +  W N  L  V+  + N+ + + +G  L  L++VL+ +       Q  + +  Q   + 
Sbjct: 379 YLSWANSVLCEVNSSVENVSS-IQEGRVLCELIDVLAPEAGLLDKVQ-ASGKSGQRAFIY 206

Query: 82  VALEFLDRESIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWDEEEDEEAKKQTP 141
            AL+ +    IK+V   ++ I+DG++K +L ++W LIL+Y I    +      +      
Sbjct: 205 AALDHMKNHGIKIV-FSTQDIMDGDIKSLLDVMWLLILNYGIH---FIGNNSFQRSVGAG 38

Query: 142 KQRLLGWIQNKL 153
           K+ LL W Q +L
Sbjct: 37  KKNLLDWCQGEL 2
>32088
          Length = 1928

 Score = 36.6 bits (83), Expect = 0.13,   Method: Composition-based stats.
 Identities = 38/160 (23%), Positives = 67/160 (41%), Gaps = 21/160 (13%)
 Frame = +1

Query: 15   KKIQQNTFTRWCNEHLK----C-----VSKRIANLQTDLSDGLRLIALL-EVLSQKKMHR 64
            K  +Q  F  W N HLK    C     V++   +L   + DG+ L  L+   +S     R
Sbjct: 1255 KDGEQKAFAAWINRHLKDDPDCKHLMEVNEEGDDLFKKVGDGILLCKLINHSVSNTIDER 1434

Query: 65   KHNQRPTFRQMQLENVSVALEFLDRESIKLVSIDSKAIVDGNLKLILGLIWTLIL----- 119
              N+       + EN+++A+          V+I  + +  G   L+LGL+W +I      
Sbjct: 1435 AINKSNLNVYHRHENLTLAVNSAGSIGCTTVNIGPEDLAAGRPHLVLGLLWQIIRIGLLS 1614

Query: 120  ------HYSISMPMWDEEEDEEAKKQTPKQRLLGWIQNKL 153
                  H  +   + + E  E+  + +P++ LL W+   L
Sbjct: 1615 DINLAHHPGLVNLLREGETIEDFMRLSPEEILLRWVNYHL 1734
>11866
          Length = 893

 Score = 32.0 bits (71), Expect = 3.0,   Method: Composition-based stats.
 Identities = 19/62 (30%), Positives = 30/62 (48%)
 Frame = -3

Query: 414 TYRCSYQPTMEGVHTVHVTFAGVPIPRSPYTVTVGQACNPAACRAIGRGLQPKGVRVKET 473
           T  CS +  +  + T+    A +P+ RSP T+T+   CN  A   + R  QP   + K+ 
Sbjct: 213 TLSCSTRLGITALSTIPTLAASLPVNRSPNTITL---CNVWAALILAR*WQPLWAKGKQE 43

Query: 474 AD 475
            D
Sbjct: 42  VD 37
>02928
          Length = 1057

 Score = 32.0 bits (71), Expect = 3.6,   Method: Compositional matrix adjust.
 Identities = 19/62 (30%), Positives = 28/62 (45%)
 Frame = +3

Query: 705 SCSYVPRKPVKHTAMVSWGGVSIPNSPFRVNVGAGSHPNKVKVYGPGVAKTGLKAHEPTY 764
           SC  VP +P +     S G         R    A  HP ++++  P V K G++  E +Y
Sbjct: 483 SCQLVPAEPPEQPVCRSLGAQ-------RHQSPACVHPPRLRLSDPAVHKAGVQGQEASY 641

Query: 765 FT 766
           FT
Sbjct: 642 FT 647
>31031
          Length = 423

 Score = 31.6 bits (70), Expect = 4.5,   Method: Compositional matrix adjust.
 Identities = 15/46 (32%), Positives = 27/46 (58%), Gaps = 1/46 (2%)
 Frame = +1

Query: 2030 KVDINTEDLEDGTCRVTYCP-TEPGNYIINIKFADQHVPGSPFSVK 2074
            ++ ++  D  DG   V   P ++P + +++IK  DQHV  SP+ +K
Sbjct: 163  RMRVDVLDRHDGVYIVRLKPFSDPEHIVVSIKHNDQHVAHSPYQIK 300

 Score = 31.2 bits (69), Expect = 6.4,   Method: Compositional matrix adjust.
 Identities = 20/68 (29%), Positives = 31/68 (45%), Gaps = 2/68 (2%)
 Frame = +1

Query: 871 NAKTAGKGKLDVQFSGLAKGDAVR-DVDIIDHHDNTYTVKYIPVQQ-GPVGVNVTYGGDH 928
           N  T   G+   Q S    G  VR  VD++D HD  Y V+  P      + V++ +   H
Sbjct: 94  NHLTDSVGEGAFQVSVTQNGQRVRMRVDVLDRHDGVYIVRLKPFSDPEHIVVSIKHNDQH 273

Query: 929 IPKSPFSV 936
           +  SP+ +
Sbjct: 274 VAHSPYQI 297

 Score = 30.8 bits (68), Expect = 7.4,   Method: Compositional matrix adjust.
 Identities = 26/100 (26%), Positives = 41/100 (41%), Gaps = 14/100 (14%)
 Frame = +1

Query: 1807 GHITAYGPGLTHGVVNKPATF----TVNTK------DAGEGGLSLAIEGPS---KAEISC 1853
            G  + +GPGL     N P  +     V+TK        GEG   +++       +  +  
Sbjct: 4    GGYSGWGPGLK-SHFNVPVRYFYIQAVDTKGNHLTDSVGEGAFQVSVTQNGQRVRMRVDV 180

Query: 1854 TDNQDGTCSVSYLPVL-PGDYSILVKYNDQHIPGSPFTAR 1892
             D  DG   V   P   P    + +K+NDQH+  SP+  +
Sbjct: 181  LDRHDGVYIVRLKPFSDPEHIVVSIKHNDQHVAHSPYQIK 300
>20490
          Length = 597

 Score = 31.6 bits (70), Expect = 4.8,   Method: Composition-based stats.
 Identities = 12/32 (37%), Positives = 20/32 (62%)
 Frame = +3

Query: 1703 HVPNSPFQVTIPERPMVGVNGLDVTSLRPFDL 1734
            H P +P  +++PE P + +N  DVT L  ++L
Sbjct: 36   HTPTTPEAISLPETPRILINDADVTDLSDWNL 131
>30961
          Length = 1032

 Score = 31.2 bits (69), Expect = 5.6,   Method: Composition-based stats.
 Identities = 17/59 (28%), Positives = 26/59 (44%), Gaps = 3/59 (5%)
 Frame = -1

Query: 144 RLLGWIQNKLPQLPITNFSRDWQSGRALGALVDSCAPGLCPDWD---SWDASKPVNNAR 199
           RLL +++   P L +TN S  W S   +  +   C P      +   +W +S  V  AR
Sbjct: 444 RLLPYLRQSPPALNLTNPSASWSSANTMRTVTTECXPAATSSSNV*ATWASSTTVRKAR 268
>37715
          Length = 468

 Score = 30.4 bits (67), Expect = 8.9,   Method: Composition-based stats.
 Identities = 17/46 (36%), Positives = 24/46 (52%), Gaps = 2/46 (4%)
 Frame = -1

Query: 2543 EEILVKHMGSRLYSVSYLLKDKGEYTLVVKWGDEHIPGSPY--RIM 2586
            E ILV  +G   + VS L  D G + +V   GD H+ G  +  R+M
Sbjct: 159  ENILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVM 22
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31560675|ref|NP_032470.2| kinesin family member 3B
[Mus musculus]
         (747 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

33215                                                                 426   e-119
34477                                                                 177   1e-44
12048                                                                 170   2e-42
02896                                                                 150   3e-36
28434                                                                 145   8e-35
13148                                                                 127   1e-29
38050                                                                  86   2e-26
11818                                                                 109   3e-24
14618                                                                 107   2e-23
15043                                                                 106   3e-23
34899                                                                  95   5e-20
17748                                                                  64   2e-10
36593                                                                  52   6e-07
38061                                                                  39   0.011
>33215
          Length = 696

 Score =  426 bits (1094), Expect = e-119,   Method: Compositional matrix adjust.
 Identities = 202/226 (89%), Positives = 217/226 (96%)
 Frame = +1

Query: 144 YLEIYQEEIRDLLSKDQTKRLELKERPDTGVYVKDLSSFVTKSVKEIEHVMNVGNQNRSV 203
           YLEIYQEEIRDLLSKDQ+KRLELK RPDTGVYVKDLSSFVTKSV+EIEHVMNVGNQNRSV
Sbjct: 1   YLEIYQEEIRDLLSKDQSKRLELKXRPDTGVYVKDLSSFVTKSVREIEHVMNVGNQNRSV 180

Query: 204 GATNMNEHSSRSHAIFVITIECSEVGLDGENHIRVGKLNLVDLAGSERQAKTGAQGERLK 263
           GATNMNEHSSRSHAIF+IT+ECSE+G DGENHIRVGKLN+VDLAGSERQAKTGA G+RLK
Sbjct: 181 GATNMNEHSSRSHAIFIITVECSEIGADGENHIRVGKLNMVDLAGSERQAKTGATGDRLK 360

Query: 264 EATKINLSLSALGNVISALVDGKSTHIPYRDSKLTRLLQDSLGGNAKTVMVANVGPASYN 323
           EATKINLSLSAL NVISALVD K+THIPYRDSKLTRLLQDSLGGN+KT MVAN+GPASYN
Sbjct: 361 EATKINLSLSALSNVISALVDAKTTHIPYRDSKLTRLLQDSLGGNSKTTMVANIGPASYN 540

Query: 324 VEETLTTLRYANRAKNIKNKPRVNEDPKDALLREFQEEIARLKAQL 369
            +ETLTTLRYANRAK+IKNKP++NEDPKDALLREFQ+EI RLK QL
Sbjct: 541 FDETLTTLRYANRAKSIKNKPKINEDPKDALLREFQDEINRLKNQL 678
>34477
          Length = 811

 Score =  177 bits (450), Expect = 1e-44,   Method: Compositional matrix adjust.
 Identities = 93/142 (65%), Positives = 111/142 (78%), Gaps = 1/142 (0%)
 Frame = +3

Query: 229 GLDGENHIRVGKLNLVDLAGSERQAKTGAQGERLKEATKINLSLSALGNVISALVDGKST 288
           G DGE H+RVGKL+LVDLAGSERQAKTGA G+RLKEATKINLSLS LGNVIS +  G+  
Sbjct: 165 GGDGEQHVRVGKLHLVDLAGSERQAKTGATGQRLKEATKINLSLSTLGNVIS-VPGGRQE 341

Query: 289 HI-PYRDSKLTRLLQDSLGGNAKTVMVANVGPASYNVEETLTTLRYANRAKNIKNKPRVN 347
           H  P ++ +         G   +TVMVAN+GPA YN +ET++TLRYANRAKNIKNK ++N
Sbjct: 342 HTHPLQELQAHSPAAGLPGRQLQTVMVANMGPADYNYDETISTLRYANRAKNIKNKAKIN 521

Query: 348 EDPKDALLREFQEEIARLKAQL 369
           EDPKDALLR+FQ+EI  L+ QL
Sbjct: 522 EDPKDALLRQFQKEIEELRKQL 587

 Score =  137 bits (346), Expect = 1e-32,   Method: Compositional matrix adjust.
 Identities = 66/137 (48%), Positives = 86/137 (62%)
 Frame = +1

Query: 174 VYVKDLSSFVTKSVKEIEHVMNVGNQNRSVGATNMNEHSSRSHAIFVITIECSEVGLDGE 233
           VYVKDLS+FV  +  +++ +M +GN+NRSVG+TNMN HSSRSHAIF +T+ECSE G  G 
Sbjct: 1   VYVKDLSAFVVNNADDMDRIMTLGNKNRSVGSTNMNMHSSRSHAIFTVTVECSEKGATGS 180

Query: 234 NHIRVGKLNLVDLAGSERQAKTGAQGERLKEATKINLSLSALGNVISALVDGKSTHIPYR 293
           +             G   + +   Q    ++  +             +LVDGKSTHIPYR
Sbjct: 181 SMYVWANCTWWTWXGQRDKPRQEPQASA*RKRPRSTCLCQLWAM*YRSLVDGKSTHIPYR 360

Query: 294 DSKLTRLLQDSLGGNAK 310
           +SKLTRLLQDSLGGN+K
Sbjct: 361 NSKLTRLLQDSLGGNSK 411
>12048
          Length = 1162

 Score =  170 bits (431), Expect = 2e-42,   Method: Compositional matrix adjust.
 Identities = 113/296 (38%), Positives = 158/296 (53%), Gaps = 10/296 (3%)
 Frame = +2

Query: 57  FTFDAVYDWNAKQFELYDETFRPLVDSVLQGFNGTIFAY---GQTGTGKTYTMEGVRGDP 113
           F FD  +D   KQ ++      P + S    F  T+  Y    + G GKT+T+ G     
Sbjct: 284 FRFDKCFDQ--KQTKMKCSRM*PSL-S*TTSFKATMGQYSLMARRGGGKTFTITGGAERY 454

Query: 114 EKRGVIPNSFDHIFTHISRSQNQQYLVRASYLEIYQEEIRDLLS-KDQTKRLE------L 166
             RG+IP S  +I+    ++    + V  SYLEIY +   DLL  K +  +LE      L
Sbjct: 455 MDRGLIPRSLSYIYEQTEKNPELSFTVHISYLEIYNDSGYDLLDPKHEAAKLEDLPKVNL 634

Query: 167 KERPDTGVYVKDLSSFVTKSVKEIEHVMNVGNQNRSVGATNMNEHSSRSHAIFVITIECS 226
            E  D  +++++LS     S +E  +++ +G+ NR +  T MN+ SSRSH IF I I   
Sbjct: 635 LEDSDQNIHLRNLSVHQANSEEEALNLLFLGDTNRMIAETPMNQASSRSHCIFTIHITTR 814

Query: 227 EVGLDGENHIRVGKLNLVDLAGSERQAKTGAQGERLKEATKINLSLSALGNVISALVDGK 286
           E G      IR  K +LVDLAGSER AKT   G+ L EA  IN SL  L  VI AL +  
Sbjct: 815 ETG---SATIRRAKYHLVDLAGSERVAKTNVNGQLLTEARYINSSLHFLELVIIALSEKS 985

Query: 287 STHIPYRDSKLTRLLQDSLGGNAKTVMVANVGPASYNVEETLTTLRYANRAKNIKN 342
             H+PYR+S +T +L+DSLGGN  T M+A       N++E+++T R+A R   IKN
Sbjct: 986 RQHVPYRNSMMTSVLRDSLGGNCMTTMIATCSMEKRNMDESISTCRFAQRVAMIKN 1153
>02896
          Length = 2076

 Score =  150 bits (378), Expect = 3e-36,   Method: Compositional matrix adjust.
 Identities = 85/198 (42%), Positives = 124/198 (62%), Gaps = 2/198 (1%)
 Frame = +1

Query: 174 VYVKDLSSFVTKSVKEIEHVMNVGNQNRSVGATNMNEHSSRSHAIFVITIECSEVGLDGE 233
           ++ + L+S + ++ +E  +++  G  NRS+ A ++N  SSRSH IF + +E S   +   
Sbjct: 10  LWSRGLASHLAQNEEEALNLLFEGETNRSIAAHSLNRMSSRSHCIFTVYLE-SRSRVQSS 186

Query: 234 NHIRVGKLNLVDLAGSERQAKTGAQGERLKEATKINLSLSALGNVISALVDGKSTHIPYR 293
               V KLN VDLAGSER  K+ ++G+ + EA  IN SLS L  V+ AL D    HIP+R
Sbjct: 187 AKYTVSKLNFVDLAGSERIGKSKSEGKMVTEAMYINKSLSFLEQVVIALADKNRDHIPFR 366

Query: 294 DSKLTRLLQDSLGGNAKTVMVANVGPASYNVEETLTTLRYANRAKNIKNKPRVNE--DPK 351
            SKLT  L+DS+GGN  TV++ANV      +EET++TLR+A R   + N+P +NE  DP 
Sbjct: 367 QSKLTHYLKDSIGGNCNTVLIANVWGERAQLEETVSTLRFATRMMCVANEPAINEVYDPA 546

Query: 352 DALLREFQEEIARLKAQL 369
             L+++ Q EI  LKA+L
Sbjct: 547 -LLVKKLQREINHLKAEL 597
>28434
          Length = 777

 Score =  145 bits (365), Expect = 8e-35,   Method: Compositional matrix adjust.
 Identities = 76/115 (66%), Positives = 88/115 (76%), Gaps = 3/115 (2%)
 Frame = +2

Query: 245 DLAGSERQAKTGAQGERLKEATKINLSLSALGNVISALVDG--KSTHIPYRDSKLTRLLQ 302
           DLAGSER  +T A+G+R KE   IN  L ALGNVISAL +   K  HIPYRDSKLTRLLQ
Sbjct: 62  DLAGSERAKRTRAEGDRFKEGVNINRGLLALGNVISALGEDVQKRGHIPYRDSKLTRLLQ 241

Query: 303 DSLGGNAKTVMVANVGPASYNVEETLTTLRYANRAKNIKNKPRVNEDPK-DALLR 356
           DSLGGN+ T+MVA V PA  N+EETL TLRYA+RA+ IKNKP +N DP+ D +LR
Sbjct: 242 DSLGGNSHTLMVACVSPADSNMEETLNTLRYADRARKIKNKPVINRDPQSDEILR 406
>13148
          Length = 653

 Score =  127 bits (320), Expect = 1e-29,   Method: Compositional matrix adjust.
 Identities = 76/180 (42%), Positives = 106/180 (58%), Gaps = 1/180 (0%)
 Frame = -3

Query: 93  FAYGQTGTGKTYTMEGVRGDPEKRGVIPNSFDHIFTHI-SRSQNQQYLVRASYLEIYQEE 151
           F        KT+TMEGV G+   +G+IP     IF +I    +N ++ ++ SY EIY ++
Sbjct: 528 FCLWSNVQWKTHTMEGVLGNESLQGIIPRIVQDIFNYIYGMDENLEFHIKVSYFEIYMDK 349

Query: 152 IRDLLSKDQTKRLELKERPDTGVYVKDLSSFVTKSVKEIEHVMNVGNQNRSVGATNMNEH 211
           IRDLL   +T  L + E  +   YVK  +     S +E+  V++ G  NR V  TNMNEH
Sbjct: 348 IRDLLDVTKTN-LSVHEDKNRVPYVKGCTERFVSSPEEVMEVVDEGKSNRHVAVTNMNEH 172

Query: 212 SSRSHAIFVITIECSEVGLDGENHIRVGKLNLVDLAGSERQAKTGAQGERLKEATKINLS 271
           SSRSH++F+I ++   V  + + H   GKL LVDLAGSE+ +KTGA+G  L EA  IN S
Sbjct: 171 SSRSHSVFLIHVKQENVDSEKKLH---GKLYLVDLAGSEKVSKTGAEGAVLDEAKNINRS 1

 Score = 55.8 bits (133), Expect = 6e-08,   Method: Composition-based stats.
 Identities = 26/48 (54%), Positives = 31/48 (64%)
 Frame = -1

Query: 55  KTFTFDAVYDWNAKQFELYDETFRPLVDSVLQGFNGTIFAYGQTGTGK 102
           K F FD V   N  Q  +Y  T +P+V  VL G+NGTIFAYGQT +GK
Sbjct: 641 KVFMFDKVLKPNVTQEYVYTVTAKPIVADVLSGYNGTIFAYGQTSSGK 498
>38050
          Length = 809

 Score = 71.2 bits (173), Expect(2) = 2e-26,   Method: Compositional matrix adjust.
 Identities = 41/96 (42%), Positives = 50/96 (52%)
 Frame = -2

Query: 164 LELKERPDTGVYVKDLSSFVTKSVKEIEHVMNVGNQNRSVGATNMNEHSSRSHAIFVITI 223
           L +++ P  G Y   L      S ++IE  M  G  NR+V ATNMN  SSR+H I  IT 
Sbjct: 733 LRIRQHPKNGFYADGLQVVPVVSYEDIEKKMEAGTTNRTVAATNMNATSSRAHTIVGITF 554

Query: 224 ECSEVGLDGENHIRVGKLNLVDLAGSERQAKTGAQG 259
                   GE   +   +NLVDLAGSER   TGA G
Sbjct: 553 MQKFKNAAGEETTKSALINLVDLAGSERADSTGATG 446

 Score = 67.0 bits (162), Expect(2) = 2e-26,   Method: Compositional matrix adjust.
 Identities = 32/55 (58%), Positives = 41/55 (74%), Gaps = 3/55 (5%)
 Frame = -1

Query: 259 GERLKEATKINLSLSALGNVISALVD---GKSTHIPYRDSKLTRLLQDSLGGNAK 310
           G+RLKE   IN SLS LGN ISAL D   GK+  +P+RDS LT+LL+++LGG A+
Sbjct: 449 GDRLKEGAAINQSLSCLGNCISALADKAGGKNVKVPFRDSALTKLLKNALGGTAR 285

 Score = 85.5 bits (210), Expect = 8e-17,   Method: Compositional matrix adjust.
 Identities = 41/69 (59%), Positives = 50/69 (72%)
 Frame = -3

Query: 301 LQDSLGGNAKTVMVANVGPASYNVEETLTTLRYANRAKNIKNKPRVNEDPKDALLREFQE 360
           ++   G N+KT+MVA + PA  N EETL+TLRYA+RAK IK K  VNEDP D L+RE QE
Sbjct: 315 IEKCTGWNSKTIMVAALSPADINYEETLSTLRYADRAKQIKTKAMVNEDPTDKLIRELQE 136

Query: 361 EIARLKAQL 369
           E  +LKA L
Sbjct: 135 ENDKLKAML 109
>11818
          Length = 657

 Score =  109 bits (273), Expect = 3e-24,   Method: Compositional matrix adjust.
 Identities = 69/182 (37%), Positives = 105/182 (57%), Gaps = 6/182 (3%)
 Frame = -1

Query: 100 TGKTYTMEGVRG-----DPEKRGVIPNSFDHIFTHISRSQNQQYLVRASYLEIYQEEIRD 154
           +GKTYTM G        D +  G+IP     +F  I+   +  + V  SYLEIY E++ D
Sbjct: 657 SGKTYTMGGCYDAALSHDDDLVGIIPRILGDLFNGIAERSDYTFKVTVSYLEIYNEDLLD 478

Query: 155 LLS-KDQTKRLELKERPDTGVYVKDLSSFVTKSVKEIEHVMNVGNQNRSVGATNMNEHSS 213
           LL    Q + L ++E  +  + +K L      S+++    ++ G ++R+ GAT MN+ SS
Sbjct: 477 LLCLPSQRQPLSIREEMNGEIKIKGLKEVEVGSLEDTLMCLSQGARSRTTGATAMNDTSS 298

Query: 214 RSHAIFVITIECSEVGLDGENHIRVGKLNLVDLAGSERQAKTGAQGERLKEATKINLSLS 273
           RSHAIF + IE S+   D  +H  + K +LVDLAGSER  KT A+G+R KE   +N++++
Sbjct: 297 RSHAIFTVHIEKSKKE-DMNDHC-IAKFHLVDLAGSERAKKTRAEGDRFKEG--VNITVA 130

Query: 274 AL 275
            L
Sbjct: 129 CL 124

 Score = 60.1 bits (144), Expect = 3e-09,   Method: Composition-based stats.
 Identities = 34/56 (60%), Positives = 40/56 (71%), Gaps = 2/56 (3%)
 Frame = -3

Query: 259 GERLKEATKINLSLSALGNVISALVDG--KSTHIPYRDSKLTRLLQDSLGGNAKTV 312
           G +++   K    L ALGNVISAL +   K  HIPYRDSKLTRLLQDSLGGN+ T+
Sbjct: 169 GRQIQRRCKHYRGLLALGNVISALGEDVQKRGHIPYRDSKLTRLLQDSLGGNSHTL 2
>14618
          Length = 724

 Score =  107 bits (267), Expect = 2e-23,   Method: Compositional matrix adjust.
 Identities = 65/162 (40%), Positives = 97/162 (59%), Gaps = 6/162 (3%)
 Frame = -2

Query: 57  FTFDAVYDWNAKQFELYDETFRPLVDSVLQGFNGTIFAYGQTGTGKTYTME-GVRGDPEK 115
           F+FD V+  +  Q ++++E    LV S L G+N  IFAYGQTG+GKTYTME G+ GD + 
Sbjct: 483 FSFDRVFHPDNTQQDVFEE-ISQLVQSALDGYNVCIFAYGQTGSGKTYTMEGGLVGDEDT 307

Query: 116 RGVIPNSFDHIFTHISRSQNQ--QYLVRASYLEIYQEEIRDLLSKDQTKRLELKER---P 170
           +G+IP +   IF+     Q++  QY    S++EIY E I DLLS ++ K ++ + R    
Sbjct: 306 KGMIPRAVSQIFSTARELQDKGWQYKFTTSFVEIYNEMIGDLLSSNKXKNVKHEIRMAGR 127

Query: 171 DTGVYVKDLSSFVTKSVKEIEHVMNVGNQNRSVGATNMNEHS 212
           D  V V +L++    S  EI  ++   ++NR+V AT  NE S
Sbjct: 126 DNNVAVTNLTTVDVTSQHEIAKLLRQASENRAVAATKCNERS 1
>15043
          Length = 973

 Score =  106 bits (265), Expect = 3e-23,   Method: Compositional matrix adjust.
 Identities = 65/180 (36%), Positives = 100/180 (55%), Gaps = 7/180 (3%)
 Frame = +2

Query: 197 GNQNRSVGATNMNEHSSRSHAIFVITIE-----CSEVGLDGENHIRVGKLNLVDLAGSER 251
           G + R +GAT++  H +R+HA+F IT+E      S+VG+          + LV+LAG E 
Sbjct: 26  GRRARRMGATDIKAHRARAHAVFTITVEQKERQSSKVGVRAN-------IMLVELAGCEA 184

Query: 252 QAKTGAQGERLKEATKINLSLSALGNVISALVDGK--STHIPYRDSKLTRLLQDSLGGNA 309
              T           KI      + NV+ AL D K    H+PYR+S +TRLLQD+LGGNA
Sbjct: 185 ADATDP---------KILAGTQGVVNVLKALGDSKQIGGHVPYRESLVTRLLQDTLGGNA 337

Query: 310 KTVMVANVGPASYNVEETLTTLRYANRAKNIKNKPRVNEDPKDALLREFQEEIARLKAQL 369
            T+M+  V P   + + T + L+Y   AK +KN  R+N D    ++ E +++I+RL+ ++
Sbjct: 338 MTLMLVTVSPLDKSYQTTQSALQYGQFAKTVKNHARMNLDDTQDIIAEMRQDISRLRDKI 517
>34899
          Length = 564

 Score = 95.1 bits (235), Expect(2) = 5e-20,   Method: Compositional matrix adjust.
 Identities = 49/160 (30%), Positives = 91/160 (56%)
 Frame = +3

Query: 58  TFDAVYDWNAKQFELYDETFRPLVDSVLQGFNGTIFAYGQTGTGKTYTMEGVRGDPEKRG 117
           + D  Y  +AK  ++Y E    +V   L+G+N TI A+G TG+GK++ M    G+ ++ G
Sbjct: 3   SLDGAYGPDAKNGQIYQEKCDSMVQRALEGYNVTIMAFGATGSGKSFLMN---GNDQEIG 173

Query: 118 VIPNSFDHIFTHISRSQNQQYLVRASYLEIYQEEIRDLLSKDQTKRLELKERPDTGVYVK 177
           V P     +F H+ +  N++ +V AS++EI  E++ DLL+    + + +++    G++V 
Sbjct: 174 VAPMVIQQLFQHLRQRSNKESMVTASFVEILDEKMTDLLNP-HNRPMAVRQHVIKGIFVD 350

Query: 178 DLSSFVTKSVKEIEHVMNVGNQNRSVGATNMNEHSSRSHA 217
            LS  V ++ +E+  +   G + R +GAT++  H +R  A
Sbjct: 351 GLSEMVARTGEELSQLYEQGRRARRMGATDIKAHRARYDA 470

 Score = 21.2 bits (43), Expect(2) = 5e-20,   Method: Compositional matrix adjust.
 Identities = 6/12 (50%), Positives = 11/12 (91%)
 Frame = +1

Query: 213 SRSHAIFVITIE 224
           +++HA+F IT+E
Sbjct: 517 TKAHAVFTITVE 552
>17748
          Length = 621

 Score = 64.3 bits (155), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 42/126 (33%), Positives = 67/126 (53%), Gaps = 6/126 (4%)
 Frame = -3

Query: 83  SVLQGFNGTIFAYGQTGTGKTYTMEG-----VRGDPEKRGVIPNSFDHIFTHISRSQNQQ 137
           ++ +G+N T+ AYGQTG+GKT++M G     ++ D E  G+IP     +F  I    +  
Sbjct: 379 ALFKGYNATVLAYGQTGSGKTFSMGGCYEASLKLDEEAMGIIPRIIKDLFNGIQERPDHT 200

Query: 138 YLVRASYLEIYQEEIRDLLSK-DQTKRLELKERPDTGVYVKDLSSFVTKSVKEIEHVMNV 196
           + V  SYLEIY EE+ BLL    Q + L ++E  +  + +K L      SV +    ++ 
Sbjct: 199 FKVTVSYLEIYNEELLBLLCPLSQRQPLTIREELNGEIKIKGLKEVTVGSVDDTLDCLSQ 20

Query: 197 GNQNRS 202
           G Q R+
Sbjct: 19  GAQLRT 2
>36593
          Length = 466

 Score = 52.4 bits (124), Expect = 6e-07,   Method: Compositional matrix adjust.
 Identities = 24/42 (57%), Positives = 30/42 (71%)
 Frame = +1

Query: 296 KLTRLLQDSLGGNAKTVMVANVGPASYNVEETLTTLRYANRA 337
           KLT LLQ+SLGGN+KT+M  NV P   N  ETL +LR+A + 
Sbjct: 1   KLTYLLQNSLGGNSKTLMFVNVSPKEENFSETLNSLRFATKV 126
>38061
          Length = 206

 Score = 38.5 bits (88), Expect = 0.011,   Method: Composition-based stats.
 Identities = 18/28 (64%), Positives = 22/28 (78%)
 Frame = -3

Query: 313 MVANVGPASYNVEETLTTLRYANRAKNI 340
           +VA V PA  N+EETL TLRYA+RA+ I
Sbjct: 84  LVACVSPADSNMEETLNTLRYADRARKI 1
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6753620|ref|NP_034158.1| DEAD/H (Asp-Glu-Ala-Asp/His)
box polypeptide 3, X-linked [Mus musculus]
         (662 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

01517                                                                 424   e-119
00621                                                                 290   1e-78
17544                                                                 277   9e-75
04883                                                                 222   3e-58
09327                                                                 219   4e-57
01062                                                                 208   6e-54
09316                                                                 167   2e-41
33025                                                                 159   2e-40
02054                                                                  95   5e-33
00739                                                                 130   1e-30
00162                                                                 118   2e-30
02498                                                                  78   3e-30
07310                                                                 125   6e-29
22006                                                                 103   2e-22
30136                                                                 101   7e-22
14337                                                                  99   7e-21
19525                                                                  96   4e-20
19640                                                                  93   1e-19
34295                                                                  83   3e-16
12995                                                                  82   5e-16
19172                                                                  81   1e-15
00617                                                                  78   1e-14
11160                                                                  65   8e-13
39583                                                                  71   2e-12
11624                                                                  70   2e-12
17708                                                                  69   6e-12
19151                                                                  63   4e-10
12121                                                                  62   6e-10
10649                                                                  55   7e-08
31220                                                                  55   9e-08
03381                                                                  54   2e-07
08036                                                                  53   3e-07
31899                                                                  52   9e-07
11423                                                                  44   2e-04
06438                                                                  44   2e-04
33083                                                                  43   4e-04
34134                                                                  41   0.001
01797                                                                  41   0.002
31113                                                                  39   0.005
01821                                                                  36   0.056
18180                                                                  33   0.48 
33543                                                                  32   1.0  
>01517
          Length = 2605

 Score =  424 bits (1091), Expect = e-119,   Method: Compositional matrix adjust.
 Identities = 207/252 (82%), Positives = 227/252 (90%), Gaps = 2/252 (0%)
 Frame = +2

Query: 328 VDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPK 387
           VDMMERGKIG+D C YLVLDEADRMLDMGFEPQIRRIVE+DTMPP G R T+MFSATFPK
Sbjct: 2   VDMMERGKIGMDHCNYLVLDEADRMLDMGFEPQIRRIVEKDTMPPTGQRQTLMFSATFPK 181

Query: 388 EIQMLARDFLDEYIFLAVGRVGSTSENITQKVVWVEEIDKRSFLLDLLNA--TGKDSLTL 445
           EIQ+LARDFLD YIFLAVGRVGSTSENITQKVVWVEE +KRSFLLDLL A  TG +SLTL
Sbjct: 182 EIQLLARDFLDNYIFLAVGRVGSTSENITQKVVWVEEPEKRSFLLDLLMASGTGPESLTL 361

Query: 446 VFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGL 505
           VFVETKKGADSLE FL +E Y  TSIHGDRSQR+RE+AL  F++G  PILVATAVAARGL
Sbjct: 362 VFVETKKGADSLEQFLMYENYPATSIHGDRSQREREDALRVFKNGDRPILVATAVAARGL 541

Query: 506 DISNVKHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNERNINITKDLLDLLVEAKQ 565
           DI NV+HVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFN++N NI +D+LDLL EA Q
Sbjct: 542 DIPNVRHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNDKNRNIARDMLDLLTEANQ 721

Query: 566 EVPSWLENMAFE 577
           EVPSWLE++A++
Sbjct: 722 EVPSWLESLAYD 757
>00621
          Length = 2263

 Score =  290 bits (742), Expect = 1e-78,   Method: Compositional matrix adjust.
 Identities = 161/421 (38%), Positives = 240/421 (57%), Gaps = 21/421 (4%)
 Frame = +1

Query: 164 DDIPVEATGNNCPPHIESFSDVEMGEIIMGNIELTRYTRPTPVQKHAIPIIKEKRDLMAC 223
           +D  +   G   P  I  + + ++G  IM  I+   Y  PTP+Q  AIPI  + RD++  
Sbjct: 205 EDYNISCKGGRIPNPIRFWKESDLGADIMEVIDRVGYKEPTPIQMQAIPIGLQNRDIIGV 384

Query: 224 AQTGSGKTAAFLLPILSQIYADGPGEALRAMKENGRYGRRKQYPISLVLAPTRELAVQIY 283
           A+TGSGKTAAFL+P+L  I         +++ +  R     Q P +++LAPTRELA QI 
Sbjct: 385 AETGSGKTAAFLIPLLVWI---------QSLPKIERLEDADQGPYAVILAPTRELAQQIE 537

Query: 284 EEARKFSYRSRVRPCVVYGGAEIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKY 343
           EE RKF     +R   V GG    +Q   L++GC +++ATPGR++D++E   + L+ C Y
Sbjct: 538 EETRKFGEGLGIRVVSVIGGISREEQGFKLQQGCEVVIATPGRMIDVLENRYLVLNQCTY 717

Query: 344 LVLDEADRMLDMGFEPQIRRIVE---------------------QDTMPPKGVRHTMMFS 382
           +V+DEADRM++MGFEP++R+I++                     Q+       R T+MF+
Sbjct: 718 VVMDEADRMINMGFEPEVRKILDYLPVSNQKPDNDDAEDDLKMLQNFKSKHKYRQTVMFT 897

Query: 383 ATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVVWVEEIDKRSFLLDLLNATGKDS 442
           AT P +++ LAR FL     + +G VG   E + Q V  + E +KR  L+++LNA G D 
Sbjct: 898 ATMPPQVERLARTFLRRPTVVYIGNVGKPVERVEQIVYMLTESEKRKKLIEVLNA-GVDP 1074

Query: 443 LTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAA 502
             ++FV  KKGAD L   L   G+  T++HG + Q  RE AL   + G   I+VAT VA 
Sbjct: 1075PIIIFVNQKKGADVLAKSLEKMGFNATTLHGGKGQEQREYALASLKGGAKDIMVATDVAG 1254

Query: 503 RGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNERNINITKDLLDLLVE 562
           RG+DI +V  V+N+D+   IE+Y HRIGRTGR G  G + +F  + +  +  DL  L++ 
Sbjct: 1255RGIDIKDVSLVLNYDMARTIEDYTHRIGRTGRAGKEGTSITFLTKEDSMVFYDLKQLMLS 1434

Query: 563 A 563
           +
Sbjct: 1435S 1437
>17544
          Length = 1047

 Score =  277 bits (709), Expect = 9e-75,   Method: Compositional matrix adjust.
 Identities = 132/201 (65%), Positives = 163/201 (81%), Gaps = 1/201 (0%)
 Frame = +2

Query: 119 FERGGNSRWCDKSDEDDWSKPLPPSERLEQELFSGGNTGINFEKYDDIPVEATGNNCPPH 178
           + R  N + C +  ++DWS PLP + RLEQELF G NTGINF+KY+DIPVEATG++ PPH
Sbjct: 449 YNRWDNRQDCQQDGKEDWSVPLPQNSRLEQELFGGNNTGINFDKYEDIPVEATGDSPPPH 628

Query: 179 IESFSDVEMGEIIMGNIELTRYTRPTPVQKHAIPIIKEKRDLMACAQTGSGKTAAFLLPI 238
           I SF +  +GEII  NI L++Y +PTPVQK A+PI+  KRDLMACAQTGSGKTAAFLLPI
Sbjct: 629 INSFEECTLGEIIRNNIVLSKYNKPTPVQKFALPIVLGKRDLMACAQTGSGKTAAFLLPI 808

Query: 239 LSQIYADGPG-EALRAMKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRP 297
           L+Q+Y +GP  EAL+  +  G   RRK YPI+L+LAPTRELA QIY+EARKF+YRSR+RP
Sbjct: 809 LNQVYENGPTPEALQQNQSRGY--RRKMYPIALILAPTRELASQIYDEARKFAYRSRLRP 982

Query: 298 CVVYGGAEIGQQIRDLERGCH 318
           CVVYGGA+IG Q+RDL++GCH
Sbjct: 983 CVVYGGADIGAQMRDLDKGCH 1045
>04883
          Length = 1155

 Score =  222 bits (566), Expect = 3e-58,   Method: Compositional matrix adjust.
 Identities = 120/270 (44%), Positives = 163/270 (60%), Gaps = 1/270 (0%)
 Frame = +3

Query: 168 VEATGNNCPPHIESFSDVEMGEIIMGNIELTRYTRPTPVQKHAIPIIKEKRDLMACAQTG 227
           +  +G   P  I +F++V   + +M  +    +T PTP+Q  + P+    +DL+  AQTG
Sbjct: 324 ISVSGKFVPNPILTFTEVNFPDYVMNQVRRNSWTAPTPIQSQSWPVAMAGKDLVGIAQTG 503

Query: 228 SGKTAAFLLPILSQIYADGPGEALRAMKENGRYGRRKQYPISLVLAPTRELAVQIYEEAR 287
           SGKT AF+LP +  I                 Y  R   PI L L PTRELA Q+ E A+
Sbjct: 504 SGKTLAFMLPAIVHINHQA-------------YLERGDGPIVLALVPTRELAQQVQEVAQ 644

Query: 288 KFSYRSRVRPCVVYGGAEIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLD 347
           +F + SRVR   VYGGA  G Q+RDLERG  + +ATPGRL+D +E  +  L  C YLVLD
Sbjct: 645 EFGHASRVRSVCVYGGAPRGPQLRDLERGAEICIATPGRLIDFLESNRTNLRRCTYLVLD 824

Query: 348 EADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGR 407
           EADRMLDMGFEPQIR+I+EQ     +  R T+M+SAT+PKE++ LA DF+DEY+ + +G 
Sbjct: 825 EADRMLDMGFEPQIRKIIEQI----RPDRQTLMWSATWPKEVRKLAEDFIDEYVQVNIGA 992

Query: 408 VGSTS-ENITQKVVWVEEIDKRSFLLDLLN 436
           +  T+  NI Q +    E +K   L+ LLN
Sbjct: 993 LELTANHNILQIIDVCMEHEKEDKLVKLLN 1082
>09327
          Length = 1087

 Score =  219 bits (557), Expect = 4e-57,   Method: Compositional matrix adjust.
 Identities = 116/238 (48%), Positives = 163/238 (68%), Gaps = 3/238 (1%)
 Frame = +2

Query: 271 VLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGAEIGQQIRDLERGCHLLVATPGRLVDM 330
           +L PTRELA Q+ E A +F + SRVR   VYGGA+ G Q+R+L+RG  + +ATPGRL+D 
Sbjct: 20  LLVPTRELAQQVQEVAVEFGHSSRVRSVCVYGGAQRGPQLRELDRGAEICIATPGRLIDF 199

Query: 331 MERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQ 390
           +E  +  L  C YLVLDEADRMLDMGFEPQIR+IVEQ  + P   R T+M+SAT+PKE++
Sbjct: 200 LESNRTNLRRCTYLVLDEADRMLDMGFEPQIRKIVEQ--IRPD--RQTLMWSATWPKEVR 367

Query: 391 MLARDFLDEYIFLAVGRVGSTS-ENITQKVVWVEEIDKRSFLLDLLN--ATGKDSLTLVF 447
            LA DF+ EY  + +G +  T+  NI Q +    + +K   L+ LLN     K++ TL+F
Sbjct: 368 KLAEDFIMEYTQINIGALQLTANHNILQIIDVCMDHEKEEKLVKLLNEIMQEKENRTLIF 547

Query: 448 VETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGL 505
           VETK+  D +   +  +G+    IHGD+SQ++R+  L+ FR+G+ P+L+AT VA+RGL
Sbjct: 548 VETKRKCDDIHRRMKRDGWPVLCIHGDKSQQERDWVLNDFRNGRCPVLLATDVASRGL 721
>01062
          Length = 2138

 Score =  208 bits (529), Expect = 6e-54,   Method: Compositional matrix adjust.
 Identities = 135/404 (33%), Positives = 210/404 (51%), Gaps = 4/404 (0%)
 Frame = -3

Query: 157  GINFEKYDDIPVEATGNNCPPHIESFSDVEMGEIIMGNIELTRYTRPTPVQKHAIPIIKE 216
             + FE  +D+ V  T          F ++ + E ++  I    + +P+ +Q+ A+  I +
Sbjct: 2118 AVEFETSEDVEVTPT----------FDNMGIREELLRGIYAYGFEKPSAIQQRAVKPIVK 1969

Query: 217  KRDLMACAQTGSGKTAAFLLPILSQIYADGPGEALRAMKENGRYGRRKQYPISLVLAPTR 276
             RD++A AQ+G+GKTA F + +L  +        LR  +             +L+L+PTR
Sbjct: 1968 GRDVIAQAQSGTGKTATFSISVLQCLDIQ-----LRETQ-------------ALILSPTR 1843

Query: 277  ELAVQIYEEARKFSYRSRVRPCVVYGGAEIGQQIRDLERGCHLLVATPGRLVDMMERGKI 336
            ELA QI +          V+     GG  IG+ IR L+ G H++  TPGR+ DM++R  +
Sbjct: 1842 ELATQIQKVMLALGDYMNVQCHSCIGGTNIGEDIRKLDYGQHIVSGTPGRVFDMIKRRNL 1663

Query: 337  GLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDF 396
                 K ++LDEAD ML+ GF+ QI  +     +PP      ++ SAT P EI  +   F
Sbjct: 1662 RTRSIKMMILDEADEMLNKGFKEQIYDVYRY--LPPAT--QVILISATLPHEILEMTNKF 1495

Query: 397  LDEYIFLAVGRVGSTSENITQKVVWVE----EIDKRSFLLDLLNATGKDSLTLVFVETKK 452
            + + I + V R   T E I Q  V VE    + D    L D L  T      ++F  TK+
Sbjct: 1494 MTDPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQ----AVIFCNTKR 1327

Query: 453  GADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVKH 512
              D L + +    +  +S+HGD  Q++RE  +  FR+G S +L+ T V ARG+D+  V  
Sbjct: 1326 KVDWLTEKMREANFTVSSMHGDMPQKEREAIMKVFRAGDSRVLITTDVWARGIDVQQVSL 1147

Query: 513  VINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNERNINITKDL 556
            VIN+DLP++ E Y+HRIGR+GR G  G+A +F    +I I +D+
Sbjct: 1146 VINYDLPNNRELYIHRIGRSGRFGRKGVAINFVKNDDIRILRDI 1015
>09316
          Length = 2312

 Score =  167 bits (422), Expect = 2e-41,   Method: Compositional matrix adjust.
 Identities = 115/385 (29%), Positives = 187/385 (48%), Gaps = 4/385 (1%)
 Frame = +2

Query: 169  EATGNNCPPHIESFSDVEMGEIIMGNIELTRYTRPTPVQKHAIPIIKEKRDLMACAQTGS 228
            +  G     H   F D  +   ++  I    +  P+ VQ   IP      D++  A++G 
Sbjct: 812  DVKGTYVSIHSSGFRDFLLKPELLRAIIDCGFEHPSEVQHECIPQAILSMDVLCQAKSGM 991

Query: 229  GKTAAFLLPILSQIY-ADGPGEALRAMKENGRYGRRKQYPISLVLAPTRELAVQIYEEAR 287
            GKTA F+L  L Q+   DG    L                   V+A TRELA QI +E  
Sbjct: 992  GKTAVFVLATLQQLEPVDGQVSVL-------------------VMAHTRELAFQISKEYE 1114

Query: 288  KFS-YRSRVRPCVVYGGAEIGQQIRDLERGC-HLLVATPGRLVDMMERGKIGLDFCKYLV 345
            +FS Y + V+  V +GG  + +    L + C H++V TPGRL  + +   + L   K+ +
Sbjct: 1115 RFSKYMNNVKIAVFFGGMSVKKDEEVLSKNCPHIVVGTPGRLHALAKANNLNLKKIKHFI 1294

Query: 346  LDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAV 405
            LDE D+ML    +  +RR V++        +  MMFSAT  KEI+ + + F+ + + + V
Sbjct: 1295 LDECDKMLA---DLDMRRDVQEIFRLTPHEKQVMMFSATLSKEIRPICKKFMQDPMEVYV 1465

Query: 406  GRVGS-TSENITQKVVWVEEIDKRSFLLDLLNATGKDSLTLVFVETKKGADSLEDFLYHE 464
                  T   + Q    +++ +K   L +LL+    + + ++FV++     +L   L  +
Sbjct: 1466 DDDSKLTLHGLQQHYCKLKDNEKNRKLFELLDVLEFNQV-IIFVKSVPRCMALSQLLLEQ 1642

Query: 465  GYACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVKHVINFDLPSDIEE 524
             +   +IH   +Q +R     QF+  +  ILVAT +  RG+DI  V  V N+D+P D + 
Sbjct: 1643 NFPAIAIHRQMTQEERLSRYQQFKDFQKRILVATNLFGRGMDIERVNIVFNYDMPEDSDT 1822

Query: 525  YVHRIGRTGRVGNLGLATSFFNERN 549
            Y+HR+ R GR G  GLA +F ++ N
Sbjct: 1823 YLHRVARAGRFGTKGLAITFVSDEN 1897
>33025
          Length = 558

 Score =  159 bits (403), Expect(2) = 2e-40,   Method: Compositional matrix adjust.
 Identities = 79/158 (50%), Positives = 107/158 (67%)
 Frame = +3

Query: 282 IYEEARKFSYRSRVRPCVVYGGAEIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFC 341
           IY EA KFS  + V P VVYG  +   Q   + +G +L+V TPGRL+D +    I L  C
Sbjct: 3   IYGEAYKFSRGTDVHPSVVYGATDRRYQKSRIMKGANLVVGTPGRLLDFIGDQTISLGKC 182

Query: 342 KYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYI 401
           +YL+LDEADRMLDMGFEP+IR++V+   MPPK  R T+MFSATF ++IQ LA DFL++Y+
Sbjct: 183 QYLILDEADRMLDMGFEPEIRKLVDTHGMPPKTQRQTLMFSATFKEDIQRLAGDFLNDYL 362

Query: 402 FLAVGRVGSTSENITQKVVWVEEIDKRSFLLDLLNATG 439
           F+ VG VG    ++TQ  + V+ + KR  L ++LN  G
Sbjct: 363 FITVGIVGGACSDVTQTFLEVDRLQKRDHLCEILNEMG 476

 Score = 24.6 bits (52), Expect(2) = 2e-40,   Method: Composition-based stats.
 Identities = 11/22 (50%), Positives = 13/22 (59%)
 Frame = +1

Query: 445 LVFVETKKGADSLEDFLYHEGY 466
           LVFV  K+ AD L  +L   GY
Sbjct: 490 LVFVGQKRNADFLASYLSQSGY 555
>02054
          Length = 1110

 Score = 95.1 bits (235), Expect(2) = 5e-33,   Method: Compositional matrix adjust.
 Identities = 54/178 (30%), Positives = 97/178 (54%)
 Frame = -3

Query: 392 LARDFLDEYIFLAVGRVGSTSENITQKVVWVEEIDKRSFLLDLLNATGKDSLTLVFVETK 451
           L R  L + + + V     T + + Q  +++    K ++L+ +LN    +S  +VF  T 
Sbjct: 784 LQRASLRDPVKVEVSNKYQTVDTLQQSYLFIPAKYKDAYLVSILNELAGNSF-MVFCSTC 608

Query: 452 KGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVK 511
                +   L + G+    +HG  SQ  R  +L++F+S    IL+AT VA+RGLDI +V 
Sbjct: 607 ANTQRVALLLRNLGFTAIPLHGQMSQAKRLGSLNKFKSKDRSILIATDVASRGLDIPHVD 428

Query: 512 HVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNERNINITKDLLDLLVEAKQEVPS 569
            V+N D+P+  ++Y+HR+GRT R G  G A +F ++ ++ + + +  L+ +   E P+
Sbjct: 427 VVLNLDIPTHSKDYMHRVGRTARAGRSGRAITFVSQYDVELYQRIEHLIGKKLSEYPT 254

 Score = 65.1 bits (157), Expect(2) = 5e-33,   Method: Compositional matrix adjust.
 Identities = 42/108 (38%), Positives = 67/108 (62%), Gaps = 1/108 (0%)
 Frame = -2

Query: 283  YEEARKFSYRSRVRPCVVYGGAEIGQQIRDLERGCHLLVATPGRLVDMMERGK-IGLDFC 341
            +E+A  FS    VR  +V  G ++  Q   L +  H+++ATPGRLVD +E  K   L   
Sbjct: 1085 WEKALAFS----VR*LLV--GIDMSTQALMLGKKPHIIIATPGRLVDHLENTKGFSLRAL 924

Query: 342  KYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEI 389
            K+LV+DEADR+LDM F+ ++ +I++   +P +  R+T +FSAT   ++
Sbjct: 923  KFLVMDEADRILDMNFQDEVDKILK--VIPRE--RNTYLFSATMTNKV 792
>00739
          Length = 1313

 Score =  130 bits (328), Expect = 1e-30,   Method: Compositional matrix adjust.
 Identities = 83/256 (32%), Positives = 138/256 (53%), Gaps = 4/256 (1%)
 Frame = +3

Query: 305 EIGQQIRDLERGCHLLVATPGRLVDMMER-GKIGLDFCKYLVLDEADRMLDMGFEPQIRR 363
           ++ +Q +DL    H++++TPGRL D ++      L   K+LV+DEADR+LD  F  Q+  
Sbjct: 6   DMMKQGQDLAVKPHIVISTPGRLADHIDSCDTFSLKRVKFLVMDEADRLLDDNFGAQLEP 185

Query: 364 IVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVVWVE 423
           I+ +  +P    R T++FSAT    +  L    L++          +T + + +  V V 
Sbjct: 186 ILTR--LP--SARQTLLFSATLSPTVNALRDSVLNKPFVWIQQSERATVDELQEDYVLVP 353

Query: 424 EIDKRSFLLDLLNATGKD---SLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDR 480
              K ++++ +L+   KD   S  ++F  T K A  L   L    ++C  +H    QR R
Sbjct: 354 ASMKDAYMVHILDHWLKDHPRSSLIIFTXTCKYAQILGMMLEKLQFSCAVLHSMIPQRFR 533

Query: 481 EEALHQFRSGKSPILVATAVAARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVGNLGL 540
             +L +F+S ++ IL++T VA+RGLDI  V  +IN ++P+   +YVHR+GRT R G  G 
Sbjct: 534 LSSLSRFKSNQTRILISTDVASRGLDIPTVDLIINHNIPNRPRDYVHRVGRTARAGRCGQ 713

Query: 541 ATSFFNERNINITKDL 556
           + S   E +I + K +
Sbjct: 714 SISLVTEFDIKLIKSI 761
>00162
          Length = 2322

 Score =  118 bits (295), Expect(2) = 2e-30,   Method: Compositional matrix adjust.
 Identities = 86/271 (31%), Positives = 135/271 (49%), Gaps = 5/271 (1%)
 Frame = +3

Query: 269 SLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGAEIGQQIRDLERGCHLLVATPGRLV 328
           +L++ PTRELA QIYE   K          +V GG  + ++   + +  ++++ T GRL+
Sbjct: 144 ALIITPTRELAFQIYEVLNKIRTFHDFSANLVIGGKFMWRETHLMGKT-NIVICTVGRLL 320

Query: 329 DMMERGK-IGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPK 387
             +E  +   +   K LVLDEADR++D  F   +  I+    +PP   R T++FSAT   
Sbjct: 321 HHLESTQAFDVSELKVLVLDEADRIMDSKFAQDMDSIMSH--LPP---RQTLLFSATQTM 485

Query: 388 EIQMLARDFLDEYIFLAVGRVGS--TSENITQKVVWVEEIDKRSFLLDLLNATGKDSLTL 445
            ++ LAR  L +  +++V R     T   + Q  +  E  +K S L   L     + + +
Sbjct: 486 SVKTLARLSLKDPSYVSVDRHAEYVTPTGLEQSYIVCELHEKLSLLYSFLKNHPNNKI-M 662

Query: 446 VFVETKKGADSLEDFLYHE--GYACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAAR 503
           VF++T K A  +   +  E  G +   +HG   Q  R +   +F   +  IL+ T +A R
Sbjct: 663 VFLQTCKQARYVHTVIKRERPGMSVLVLHGGIPQLRRLDIYREFCRKQHVILITTDLACR 842

Query: 504 GLDISNVKHVINFDLPSDIEEYVHRIGRTGR 534
           GLD   V  VI  D P D+  Y+HR GRT R
Sbjct: 843 GLDFPAVNWVIQLDCPVDVNTYIHRAGRTAR 935

 Score = 33.5 bits (75), Expect(2) = 2e-30,   Method: Compositional matrix adjust.
 Identities = 14/24 (58%), Positives = 19/24 (79%)
 Frame = +2

Query: 219 DLMACAQTGSGKTAAFLLPILSQI 242
           D++  A+TGSGKT AFL+PIL  +
Sbjct: 38  DVLGAAKTGSGKTLAFLIPILETL 109
>02498
          Length = 1955

 Score = 77.8 bits (190), Expect(2) = 3e-30,   Method: Compositional matrix adjust.
 Identities = 49/165 (29%), Positives = 87/165 (52%), Gaps = 9/165 (5%)
 Frame = +3

Query: 401 IFLAVGRVGSTSENITQKVVWVEEIDKRSFLLDLLNATGKDSL--TLVFVETKKGADSLE 458
           + +++ R   + +NI Q   +++   +    + L N  G  S+  +++F   +  A  L 
Sbjct: 738 VIISLKREEESLDNIKQ--YYIDCNSQEEKYVALCNIYGSISVGQSMIFCHKRSTAAWLA 911

Query: 459 DFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVKHVINFDL 518
           + +  + +A   + G+ +   R   + +FR GK  +L+ T V+ARG+D+  V  V+NFDL
Sbjct: 912 ERMTADHHAVGLLTGELTIEQRAAIIKRFREGKEKVLITTNVSARGIDVEMVTVVVNFDL 1091

Query: 519 P------SDIEEYVHRIGRTGRVGNLGLATSFF-NERNINITKDL 556
           P       D E Y+HRIGRTGR G  G+A +   N R++ I + +
Sbjct: 1092PVTQDWRPDCETYLHRIGRTGRFGKNGIAINMVDNSRSMAIMRSI 1226

 Score = 72.8 bits (177), Expect(2) = 3e-30,   Method: Compositional matrix adjust.
 Identities = 71/245 (28%), Positives = 118/245 (48%), Gaps = 12/245 (4%)
 Frame = +1

Query: 165 DIPVEATGNNCPPH-IESFSDVEMGEIIMGNIELTRYTRPTPVQKHAIPII--KEKRDLM 221
           DI V     N P + ++SF  + +   ++  +    +  P+ +Q+ A+PI+      +++
Sbjct: 85  DIEVLRKDPNSPLYSVKSFEALNLKPQLLKGVYDMGFNAPSKIQETALPILLADPPVNMI 264

Query: 222 ACAQTGSGKTAAFLLPILSQIYADGPGEALRAMKENGRYGRRKQYPISLVLAPTRELAVQ 281
           A +Q+G+GKTAAF+L +LS                  R    + +P  L LAPT ELA+Q
Sbjct: 265 AQSQSGTGKTAAFVLTMLS------------------RVDISQTFPQCLCLAPTYELALQ 390

Query: 282 IYEEARKFS-------YRSRVRPCVVYGGAEIGQQIRDLERGCHLLVATPGRLVDMMERG 334
           I E   K S        R  VR   V  G  + +QI         ++ TPG ++D   R 
Sbjct: 391 IGEVIEKMSKHMTGLEIRYAVRGERVNRGEVLSEQI---------VIGTPGTVMDWSHRF 543

Query: 335 K-IGLDFCKYLVLDEADRMLDM-GFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQML 392
           K + L+  +  VLDEAD M+ M G + Q  RI ++ +    G +  ++FSAT+ + +   
Sbjct: 544 KALPLEKLRVFVLDEADVMISMQGHQDQSTRIQKRLS---SGCQ-MLLFSATYDQVVMQF 711

Query: 393 ARDFL 397
           A+  +
Sbjct: 712 AQRII 726
>07310
          Length = 712

 Score =  125 bits (314), Expect = 6e-29,   Method: Compositional matrix adjust.
 Identities = 70/219 (31%), Positives = 119/219 (54%)
 Frame = +2

Query: 326 RLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATF 385
           R++D+M +  +  D C  LVLDEAD++L   F+  +  I+    +PP+  R  +++SATF
Sbjct: 2   RILDLMNKRLVKPDTCGILVLDEADKLLSQDFKGMLDNIIAH--LPPQ--RQILLYSATF 169

Query: 386 PKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVVWVEEIDKRSFLLDLLNATGKDSLTL 445
           P  ++   + +L     + +     T + +TQ   +V+E  ++   L+ L +  + + ++
Sbjct: 170 PLSVEQFMKKYLKNPYEINLME-ELTLKGVTQYYAFVQE-KQKVHCLNTLFSKLQINQSI 343

Query: 446 VFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGL 505
           +F  + +  + L   +   GY+C  IH   +Q+ R    H FR G    LV + +  RG+
Sbjct: 344 IFCNSTQRVELLAKKITELGYSCYYIHAKMNQQHRNRVFHDFRQGLCRNLVCSDLFTRGI 523

Query: 506 DISNVKHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSF 544
           DI  V  VINFD P   E Y+HRIGR+GR G+LG+A + 
Sbjct: 524 DIQAVNVVINFDFPKHAETYLHRIGRSGRYGHLGVAINL 640
>22006
          Length = 3414

 Score =  103 bits (257), Expect = 2e-22,   Method: Compositional matrix adjust.
 Identities = 57/153 (37%), Positives = 89/153 (58%)
 Frame = +2

Query: 203  PTPVQKHAIPIIKEKRDLMACAQTGSGKTAAFLLPILSQIYADGPGEALRAMKENGRYGR 262
            PTP+Q+  IP+I E +D++A A+TGSGKTAAFL+P+L +            +K +   G 
Sbjct: 3005 PTPIQRKTIPVIMEGKDMVAMARTGSGKTAAFLVPMLER------------LKMHSSKGA 3148

Query: 263  RKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGAEIGQQIRDLERGCHLLVA 322
            R     +L+L+PTRELA+Q  +  ++      +R  V+ GG  +  Q   L +   +++A
Sbjct: 3149 R-----ALILSPTRELALQTLKFTKELGKFLDLRAAVILGGDRMEDQFSALHQNPDIIIA 3313

Query: 323  TPGRLVDMMERGKIGLDFCKYLVLDEADRMLDM 355
            TPGRL+ ++   K  L    Y+V DEADR+ +M
Sbjct: 3314 TPGRLLHVLVEMKKSLKEVIYVVFDEADRLFEM 3412
>30136
          Length = 524

 Score =  101 bits (252), Expect = 7e-22,   Method: Composition-based stats.
 Identities = 58/160 (36%), Positives = 85/160 (53%)
 Frame = +2

Query: 164 DDIPVEATGNNCPPHIESFSDVEMGEIIMGNIELTRYTRPTPVQKHAIPIIKEKRDLMAC 223
           D+  +   G    P I+ F++  + + ++  I    Y  PTP+Q    PI     + +  
Sbjct: 86  DEHEITVRGQAANP-IQDFAEAYLPDYVIKEIRRQGYKSPTPIQAQGWPIAMSGANFVGI 262

Query: 224 AQTGSGKTAAFLLPILSQIYADGPGEALRAMKENGRYGRRKQYPISLVLAPTRELAVQIY 283
           A+TGSGKT  ++LP +  I    P +             R + PI+LVLAPTRELA QI 
Sbjct: 263 AKTGSGKTLGYILPAIVHINNQQPLQ-------------RGEGPIALVLAPTRELAQQIQ 403

Query: 284 EEARKFSYRSRVRPCVVYGGAEIGQQIRDLERGCHLLVAT 323
           + A +F   S VR   V+GGA  G Q+RDL+RGC +++AT
Sbjct: 404 QVATEFGSSSYVRNTCVFGGAPKGGQMRDLQRGCEIVIAT 523
>14337
          Length = 693

 Score = 98.6 bits (244), Expect = 7e-21,   Method: Compositional matrix adjust.
 Identities = 45/127 (35%), Positives = 75/127 (59%)
 Frame = +2

Query: 445 LVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAARG 504
           LVFV++K+ A  L      + +   +IH D+ Q +R+  +  F  G+  +LV T +  RG
Sbjct: 68  LVFVQSKQRAKELYSEFMFDKHKVDAIHADKPQAERDATVRAFTEGRVWVLVCTELMGRG 247

Query: 505 LDISNVKHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNERNINITKDLLDLLVEAK 564
           +D   +  VIN+D P++   Y+HRIGRTGR G  G A +FF E+++   + + +++ EA 
Sbjct: 248 IDFKGINLVINYDFPTNAVSYIHRIGRTGRAGVPGRAITFFTEQDVTHLRSIANIIKEAG 427

Query: 565 QEVPSWL 571
            EVP ++
Sbjct: 428 CEVPEYM 448
>19525
          Length = 585

 Score = 96.3 bits (238), Expect = 4e-20,   Method: Composition-based stats.
 Identities = 65/186 (34%), Positives = 100/186 (53%), Gaps = 4/186 (2%)
 Frame = +2

Query: 270 LVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGAEIGQQIRDLERGCHLLVATPGRLVD 329
           LVL PTRELAVQ+Y+  ++ S  +++  C+  GG +I  Q   L     ++VATPGRL+D
Sbjct: 23  LVLVPTRELAVQVYQVGQQISQYTKISICLAAGGLDIKGQEAALRLCPDIVVATPGRLID 202

Query: 330 MMERG-KIGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKE 388
            +       +   + LVLDEADRMLD  F  Q+  I+          R TM+FSAT    
Sbjct: 203 HLHNAPNFTIAHVEILVLDEADRMLDEYFAAQMTEIIRMCNFQ----RQTMLFSATMSDA 370

Query: 389 IQMLARDFLDEYIFLAVGRVGSTSENITQKVVWV---EEIDKRSFLLDLLNATGKDSLTL 445
           +Q LA   L E + + V +    +  + Q+ V +   +E D+ + +  L++ T  D   +
Sbjct: 371 VQDLASVSLKEAVKVFVNQNTDIALGLQQEFVRIRENKEGDREAIVSSLVSRTFCDK-CM 547

Query: 446 VFVETK 451
           VF++TK
Sbjct: 548 VFLQTK 565
>19640
          Length = 456

 Score = 92.8 bits (229), Expect(2) = 1e-19,   Method: Compositional matrix adjust.
 Identities = 40/88 (45%), Positives = 57/88 (64%)
 Frame = -1

Query: 446 VFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGL 505
           +F  T++  D L   +    +  +++HGD  QRDRE  + QFRSG S +L+ T + ARG+
Sbjct: 456 IFCNTRRKVDQLTQEMSSHNFTVSAMHGDMEQRDREVIMKQFRSGSSRVLITTDLLARGI 277

Query: 506 DISNVKHVINFDLPSDIEEYVHRIGRTG 533
           D+  V  VIN+DLPS+ E Y+HRIGR G
Sbjct: 276 DVQQVSLVINYDLPSNRENYIHRIGRGG 193

 Score = 22.3 bits (46), Expect(2) = 1e-19,   Method: Compositional matrix adjust.
 Identities = 10/41 (24%), Positives = 21/41 (51%)
 Frame = -3

Query: 534 RVGNLGLATSFFNERNINITKDLLDLLVEAKQEVPSWLENM 574
           R G  G+A +F  + +  I KD+        +E+P+ + ++
Sbjct: 193 RFGRKGVAINFITDDDRRILKDIEQFYHTTIEEMPANIADL 71
>34295
          Length = 694

 Score = 83.2 bits (204), Expect = 3e-16,   Method: Compositional matrix adjust.
 Identities = 51/136 (37%), Positives = 73/136 (53%)
 Frame = -1

Query: 444 TLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAAR 503
            ++F  TKK    L   L +       +HG   Q++R  AL +F+S     L+AT VAAR
Sbjct: 535 VMIFTNTKKYCQLLSMTLTNMEIENVCLHGFMRQKERVSALSRFKSNHIRTLIATDVAAR 356

Query: 504 GLDISNVKHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNERNINITKDLLDLLVEA 563
           GLDI +V+ VIN  LP   +EY+HR+GRT R G  G+A S F        +D L+LL   
Sbjct: 355 GLDIPSVQLVINHMLPRTPKEYIHRVGRTARAGRKGVAISIF-----RFPRD-LELLGAI 194

Query: 564 KQEVPSWLENMAFEHH 579
           ++E+ + L     + H
Sbjct: 193 EEEINTKLTEHPIDEH 146
>12995
          Length = 1072

 Score = 82.4 bits (202), Expect = 5e-16,   Method: Compositional matrix adjust.
 Identities = 44/120 (36%), Positives = 67/120 (55%), Gaps = 1/120 (0%)
 Frame = +3

Query: 426 DKRSFLLDLL-NATGKDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEAL 484
           DK + LL LL +   ++ LT+VFV TK   + L   L   G ACT I+    Q  R+  +
Sbjct: 81  DKEAMLLYLLRDVISENDLTVVFVATKHHVEYLNTLLTKCGIACTYIYSSLDQTARKIHV 260

Query: 485 HQFRSGKSPILVATAVAARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSF 544
            +F   +  +++ T +AARG+DI  + +V+NF  P+  + +VHR+GR  R G  G A S 
Sbjct: 261 AKFTHKQVKVMLVTDLAARGIDIPQLDNVVNFHFPAKAKLFVHRVGRVARAGRSGTAYSL 440
>19172
          Length = 484

 Score = 80.9 bits (198), Expect = 1e-15,   Method: Composition-based stats.
 Identities = 49/129 (37%), Positives = 77/129 (59%), Gaps = 3/129 (2%)
 Frame = -1

Query: 395 DFLDEYIFLAVGRVG-STSENITQKVVWVEEIDKRSFLLDLLNATG--KDSLTLVFVETK 451
           +FL+ YI + +G +  S + NI Q V   +E +K + L+ LL       ++ T++FVETK
Sbjct: 484 EFLNNYIQVNIGSLSLSANHNILQIVDVCDESEKIAKLIQLLTQISGENETKTIIFVETK 305

Query: 452 KGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVK 511
           K  D +   +  +G+   +IHGD+SQ++R+  L  FR+G+  ILVAT VAARGL     +
Sbjct: 304 KRVDEITRNISRQGWRACAIHGDKSQQERDFVLSSFRNGRHSILVATDVAARGLG----E 137

Query: 512 HVINFDLPS 520
             + F LP+
Sbjct: 136 FFVAFALPA 110
>00617
          Length = 1505

 Score = 78.2 bits (191), Expect = 1e-14,   Method: Compositional matrix adjust.
 Identities = 36/91 (39%), Positives = 57/91 (62%)
 Frame = -3

Query: 466  YACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVKHVINFDLPSDIEEY 525
            ++C  +H    QR R  +L +F+S ++ IL++T VA+RGLDI  V  +IN ++P+   +Y
Sbjct: 1482 FSCAVLHSMIPQRFRLSSLSRFKSNQTRILISTDVASRGLDIPTVDLIINHNIPNRPRDY 1303

Query: 526  VHRIGRTGRVGNLGLATSFFNERNINITKDL 556
            VHR+GRT R G  G + S   E +I + K +
Sbjct: 1302 VHRVGRTARAGRCGQSISLVTEFDIKLIKSI 1210
>11160
          Length = 646

 Score = 64.7 bits (156), Expect(2) = 8e-13,   Method: Compositional matrix adjust.
 Identities = 63/195 (32%), Positives = 88/195 (45%), Gaps = 18/195 (9%)
 Frame = -1

Query: 302 GGAEIGQQI-RDLERGCHLLVATPGRLVDMMERGKIGLDFC------KYLVLDEADRMLD 354
           GG      I + ++ G  +L+ATPGRL D+  R + G +        + LVLDEADR+LD
Sbjct: 646 GGVSCSHDISKFMKSGGSILIATPGRLDDLFSRKESGFNLAASVKALEVLVLDEADRLLD 467

Query: 355 MGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVG----- 409
           MGFE  I  I+      PK +R T +FSAT   E++ L R  L   + + V         
Sbjct: 466 MGFEASINTILGH---LPK-LRRTGLFSATQTDEVENLIRAGLRNPLRVTVKEKKLAGEA 299

Query: 410 --STSENITQKVVWVEEIDKRSFLLDLLNATGKDSLTLVFVETKKGAD----SLEDFLYH 463
              T   ++   + VE  +K S L+  L    +D L L+F  T    D     L   L H
Sbjct: 298 DQRTPSTLSNYYMIVEAEEKFSQLVKFLKTHHRDKL-LLFFSTCACVDYFSMCLTQLLKH 122

Query: 464 EGYACTSIHGDRSQR 478
                 SIH    Q+
Sbjct: 121 --MQVLSIHSKMKQK 83

 Score = 27.3 bits (59), Expect(2) = 8e-13,   Method: Composition-based stats.
 Identities = 16/34 (47%), Positives = 20/34 (58%), Gaps = 3/34 (8%)
 Frame = -3

Query: 476 SQRDREE---ALHQFRSGKSPILVATAVAARGLD 506
           SQ+D  E      +FRS  S +LV T V ARG+D
Sbjct: 104 SQQDEAEEKPVFAKFRSITSGLLVCTDVMARGVD 3
>39583
          Length = 234

 Score = 70.9 bits (172), Expect = 2e-12,   Method: Composition-based stats.
 Identities = 32/57 (56%), Positives = 43/57 (75%)
 Frame = -3

Query: 480 REEALHQFRSGKSPILVATAVAARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVG 536
           R EAL +F+ G+  +L+AT +A+RGLDI  VK VINF +PS ++ YVHR+GRT R G
Sbjct: 172 RLEALKRFKEGEIDVLLATDLASRGLDIEGVKTVINFTMPSTLKHYVHRVGRTARAG 2
>11624
          Length = 2257

 Score = 70.5 bits (171), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 32/78 (41%), Positives = 48/78 (61%)
 Frame = -1

Query: 480 REEALHQFRSGKSPILVATAVAARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVGNLG 539
           R++ L QF  GK  +LV +   ARG+D+ NVK+VI++D P  I+ Y+HR+GRT R G  G
Sbjct: 784 RKKILKQFSKGKIDLLVCSDAMARGMDVDNVKYVISYDNPPYIKTYIHRVGRTARAGRAG 605

Query: 540 LATSFFNERNINITKDLL 557
            A S   ++     K ++
Sbjct: 604 TAISLLEKKEFFHFKQMM 551

 Score = 57.8 bits (138), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 44/147 (29%), Positives = 73/147 (49%), Gaps = 10/147 (6%)
 Frame = -3

Query: 218  RDLMACAQTGSGKTAAFLLPILSQIYADGPGEALRAMKENGRYGRRKQYPISLVLAPTRE 277
            RD+   A TGSGKT A+ LPI            ++ +K+     R   +  ++++ P R+
Sbjct: 1814 RDICVSAPTGSGKTLAYTLPI------------IQCLKQ-----RMVPHVRAVIVLPVRD 1686

Query: 278  LAVQIYEEARKFSYRSRVRPCVVYG----GAEIGQQIRDLERGCH-----LLVATPGRLV 328
            LA Q+Y+    +   + ++  +V G      E    ++    G +     +LVATPGRLV
Sbjct: 1685 LAEQVYQVFCHYCADTPLKVGIVVGKTVFNVEQDTLVKKRYGGVYHSVIDILVATPGRLV 1506

Query: 329  DMMERGK-IGLDFCKYLVLDEADRMLD 354
            D +       L   ++LV+DEADRM++
Sbjct: 1505 DHINSTPGFDLSHLRFLVIDEADRMME 1425
>17708
          Length = 882

 Score = 68.9 bits (167), Expect = 6e-12,   Method: Compositional matrix adjust.
 Identities = 38/115 (33%), Positives = 64/115 (55%)
 Frame = +1

Query: 218 RDLMACAQTGSGKTAAFLLPILSQIYADGPGEALRAMKENGRYGRRKQYPISLVLAPTRE 277
           RDLM  A+TGSGKT AFL+P +  +Y       L+ M  NG           ++++PTRE
Sbjct: 553 RDLMGAAKTGSGKTLAFLIPAIELMY------KLKFMPRNGTG--------CIIISPTRE 690

Query: 278 LAVQIYEEARKFSYRSRVRPCVVYGGAEIGQQIRDLERGCHLLVATPGRLVDMME 332
           L++Q +    +          ++ GG     +++ L++G +++VATPGRL+D ++
Sbjct: 691 LSMQTFNVLTELLKYHHHTFGLIMGGVNRHDEVKKLKKGVNIIVATPGRLLDHLQ 855
>19151
          Length = 625

 Score = 62.8 bits (151), Expect = 4e-10,   Method: Composition-based stats.
 Identities = 30/68 (44%), Positives = 45/68 (66%), Gaps = 7/68 (10%)
 Frame = -3

Query: 494 ILVATAVAARGLDISNVKHVINFDLP------SDIEEYVHRIGRTGRVGNLGLATSFFN- 546
           +L+ T V +RG+DI  V  V+NFDLP      +D E Y+HRIGRTGR G  G+A +  + 
Sbjct: 620 VLITTNVLSRGIDIEQVTIVVNFDLPIDLRGNADCETYLHRIGRTGRFGKSGIAINLIDG 441

Query: 547 ERNINITK 554
           E+++N+ +
Sbjct: 440 EKSMNVCR 417
>12121
          Length = 465

 Score = 62.4 bits (150), Expect = 6e-10,   Method: Composition-based stats.
 Identities = 27/44 (61%), Positives = 32/44 (72%)
 Frame = -3

Query: 319 LLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIR 362
           + +ATPGRL+D +E  +  L  C YLVLDEADRMLDMGF P  R
Sbjct: 463 ICIATPGRLIDFLESNRTNLRRCTYLVLDEADRMLDMGFXPP*R 332

 Score = 47.0 bits (110), Expect = 2e-05,   Method: Composition-based stats.
 Identities = 21/62 (33%), Positives = 33/62 (53%)
 Frame = -2

Query: 168 VEATGNNCPPHIESFSDVEMGEIIMGNIELTRYTRPTPVQKHAIPIIKEKRDLMACAQTG 227
           +  +G   P  I +F +  + + +M  I    +T PTP+Q  + PI    +DL+  AQTG
Sbjct: 188 ITLSGRYLPNPILTFEEANLPDYVMSQIHRNNWTSPTPIQSQSWPIAMSGKDLVGIAQTG 9

Query: 228 SG 229
           SG
Sbjct: 8   SG 3
>10649
          Length = 472

 Score = 55.5 bits (132), Expect = 7e-08,   Method: Compositional matrix adjust.
 Identities = 27/70 (38%), Positives = 36/70 (51%)
 Frame = +1

Query: 465 GYACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVKHVINFDLPSDIEE 524
           G +   +HG   Q  R +   +F   +  IL+ T +A RGLD   V  VI  D P D+  
Sbjct: 64  GMSVLVLHGGIPQLRRLDIYREFCRKQHVILITTDLACRGLDFPAVNWVIQLDCPVDVNT 243

Query: 525 YVHRIGRTGR 534
           Y+HR GRT R
Sbjct: 244 YIHRAGRTAR 273
>31220
          Length = 818

 Score = 55.1 bits (131), Expect = 9e-08,   Method: Compositional matrix adjust.
 Identities = 24/54 (44%), Positives = 33/54 (61%)
 Frame = +2

Query: 501 AARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNERNINITK 554
           A+RG+D   V +VINFD P D+  Y+HR GRT R  N G   SF + + + I +
Sbjct: 161 ASRGIDFQGVNNVINFDFPLDVTSYIHRAGRTARGNNTGSVLSFVSVKELPINQ 322
>03381
          Length = 1206

 Score = 54.3 bits (129), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 25/71 (35%), Positives = 41/71 (57%)
 Frame = +3

Query: 505 LDISNVKHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNERNINITKDLLDLLVEAK 564
           LDI +++ V+N+D+  DI+ + HR+GRTGR G  G A +   +++      L+  L  A 
Sbjct: 3   LDIPHIRTVVNYDVARDIDTHTHRVGRTGRAGEKGSAYTLITDKDKEFAPLLVRNLEGAN 182

Query: 565 QEVPSWLENMA 575
           Q  P  L ++A
Sbjct: 183 QTPPPALLDLA 215
>08036
          Length = 1226

 Score = 53.1 bits (126), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 26/75 (34%), Positives = 42/75 (56%)
 Frame = +3

Query: 502 ARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNERNINITKDLLDLLV 561
           ARG+D  NV +VINF+ P  ++ Y+HR+GRT R    G A S  + R+ N   + ++   
Sbjct: 612 ARGIDFQNVSNVINFEFPKTVDAYIHRVGRTARGDKQGCALSLIS-RHENDQFEAVEEAQ 788

Query: 562 EAKQEVPSWLENMAF 576
           +  ++ PS  +   F
Sbjct: 789 KTDKDSPSVFKPFMF 833
>31899
          Length = 453

 Score = 52.0 bits (123), Expect = 9e-07,   Method: Compositional matrix adjust.
 Identities = 31/103 (30%), Positives = 55/103 (53%)
 Frame = -1

Query: 182 FSDVEMGEIIMGNIELTRYTRPTPVQKHAIPIIKEKRDLMACAQTGSGKTAAFLLPILSQ 241
           F+ + + + ++  ++   + RP+P+Q  AIP+ +   DL+  A++G+GKT  F       
Sbjct: 339 FASLLLSKPVLNGLKNAGFERPSPIQLKAIPLGRCGLDLIVQAKSGTGKTCVF------- 181

Query: 242 IYADGPGEALRAMKENGRYGRRKQYPISLVLAPTRELAVQIYE 284
                   ++ A++      R  Q    LVLAPTRE+A+QI+E
Sbjct: 180 --------SVVALEGIETTARSTQV---LVLAPTREIALQIWE 85
>11423
          Length = 1434

 Score = 43.9 bits (102), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 18/47 (38%), Positives = 28/47 (59%)
 Frame = -2

Query: 511  KHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNERNINITKDLL 557
            K+VI++D P  I+ Y+HR+GRT R G  G A S   ++     K ++
Sbjct: 1397 KYVISYDNPPYIKTYIHRVGRTARAGRAGTAISLLEKKEFFHFKQMM 1257
>06438
          Length = 989

 Score = 43.9 bits (102), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 18/39 (46%), Positives = 22/39 (56%)
 Frame = +1

Query: 496 VATAVAARGLDISNVKHVINFDLPSDIEEYVHRIGRTGR 534
           +   +A RGLD   V  VI  D P D+  Y+HR GRT R
Sbjct: 25  LTVTLACRGLDFPAVNWVIQLDCPVDVNTYIHRAGRTAR 141
>33083
          Length = 1931

 Score = 43.1 bits (100), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 23/69 (33%), Positives = 36/69 (52%), Gaps = 1/69 (1%)
 Frame = +1

Query: 503 RGLDISNVKHVINFDLPSDIEEYVHRIGRTGR-VGNLGLATSFFNERNINITKDLLDLLV 561
           RGLDI  V  ++ +D P + +EY+HR+GRT R  G+ G A        +   K L    V
Sbjct: 1   RGLDIPQVDWIVQYDPPDESKEYIHRVGRTARGEGSSGKALLLLQPEELGFLKFLRAAKV 180

Query: 562 EAKQEVPSW 570
           + ++   +W
Sbjct: 181 KVQEMDFNW 207
>34134
          Length = 271

 Score = 41.2 bits (95), Expect = 0.001,   Method: Composition-based stats.
 Identities = 25/65 (38%), Positives = 31/65 (47%)
 Frame = +3

Query: 211 IPIIKEKRDLMACAQTGSGKTAAFLLPILSQIYADGPGEALRAMKENGRYGRRKQYPISL 270
           +PI    RD +  AQTGSGKT +F+LP +  I      E             R   PI+L
Sbjct: 84  VPIAMSGRDCVGIAQTGSGKTLSFILPAIVHINHQPTLE-------------RGDGPIAL 224

Query: 271 VLAPT 275
           VL PT
Sbjct: 225 VLVPT 239
>01797
          Length = 1448

 Score = 40.8 bits (94), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 23/100 (23%), Positives = 49/100 (49%), Gaps = 3/100 (3%)
 Frame = -3

Query: 440 KDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFR---SGKSPILV 496
           +DS  L+F +  +  D LED+ +  G+    + G     DR++++ +F    S K   ++
Sbjct: 573 QDSRVLIFSQMTRMLDILEDYCFWRGFDYCRLDGSTPHEDRQKSILEFNAPDSSKFVFML 394

Query: 497 ATAVAARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVG 536
           +T     G++++    VI +D   + +  +  + R  R+G
Sbjct: 393 STRAGGLGINLATADIVILYDSDWNPQVDLQAMDRAHRIG 274
>31113
          Length = 500

 Score = 39.3 bits (90), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 32/109 (29%), Positives = 45/109 (41%), Gaps = 11/109 (10%)
 Frame = +3

Query: 445 LVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSP---ILVATAVA 501
           LVF +       +ED+L + G     + G     DR + L  F    SP    L++T   
Sbjct: 78  LVFCQMTSLMSIMEDYLMYRGIRYLRLDGMTKSEDRGQLLEMFNRKDSPYFLFLLSTRAG 257

Query: 502 ARGLDISNVKHVINFDLPSD--------IEEYVHRIGRTGRVGNLGLAT 542
             GL++     VI FD  SD         ++  HRIG+   V  L L T
Sbjct: 258 GLGLNLQTADTVIIFD--SDWNPHQDLQAQDRAHRIGQKNEVRVLRLMT 398
>01821
          Length = 910

 Score = 35.8 bits (81), Expect = 0.056,   Method: Compositional matrix adjust.
 Identities = 17/40 (42%), Positives = 23/40 (57%)
 Frame = +1

Query: 495 LVATAVAARGLDISNVKHVINFDLPSDIEEYVHRIGRTGR 534
           LV+T V   GLDI +V  ++ +D        V R+GRTGR
Sbjct: 13  LVSTCVGEEGLDIGDVDLIVCYDAHKSPVRLVQRMGRTGR 132
>18180
          Length = 1017

 Score = 32.7 bits (73), Expect = 0.48,   Method: Compositional matrix adjust.
 Identities = 26/108 (24%), Positives = 45/108 (41%), Gaps = 2/108 (1%)
 Frame = -3

Query: 431 LLDLLNATGKDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSG 490
           LL  L A   D   L+F +     D ++D+L + GY    + G     +R  A+  F   
Sbjct: 421 LLKWLQAN--DHKVLLFSQMTHMLDIVQDYLGYRGYTYERLDGSVRGEERFLAVQNFNQN 248

Query: 491 KSP--ILVATAVAARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVG 536
                 L++T    +GL+++    VI  D   + +  +    R  R+G
Sbjct: 247 DETFVFLLSTKAGGQGLNLTAADTVIFIDSDFNPQNDLQAAARAHRIG 104
>33543
          Length = 471

 Score = 31.6 bits (70), Expect = 1.0,   Method: Compositional matrix adjust.
 Identities = 12/20 (60%), Positives = 15/20 (75%)
 Frame = +3

Query: 525 YVHRIGRTGRVGNLGLATSF 544
           Y+HR+GR GR G  GLA +F
Sbjct: 6   YLHRVGRAGRFGTRGLAITF 65
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6755809|ref|NP_035732.1| talin 1 [Mus musculus]
         (2541 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

09133                                                                 397   e-119
30501                                                                  78   5e-14
08616                                                                  61   5e-09
17332                                                                  59   3e-08
17228                                                                  37   0.077
>09133
          Length = 1844

 Score =  397 bits (1019), Expect(2) = e-119,   Method: Compositional matrix adjust.
 Identities = 251/482 (52%), Positives = 312/482 (64%), Gaps = 18/482 (3%)
 Frame = +1

Query: 2037 AAGSQEKLAQAAQSSVATITRLADVVKLGAASLGAEDPETQVVLINAVKDVAKALGDLIS 2096
            AA +QE+LA AAQ++V TITRLADVVK+GA SLG E PE QV+LINAVKDVA AL DLIS
Sbjct: 103  AASNQEQLAAAAQAAVKTITRLADVVKIGAGSLGPEQPEAQVLLINAVKDVASALSDLIS 282

Query: 2097 ATKAAAGKVGDDPAVWQLKNSAKVMVTNVTSLLKTVKAVEDEATKGTRALEATTEHIRQE 2156
            ATK A+GK   DPA+  LK+SAKVMVTNVTSLLKTVK+VEDEA +GTRALE+T E I QE
Sbjct: 283  ATKNASGKPVSDPAMLHLKDSAKVMVTNVTSLLKTVKSVEDEAVRGTRALESTIEAIGQE 462

Query: 2157 LAVFC----------------SPEPPAKTSTPEDFIRMTKGITMATAKAVAAGNSCRQED 2200
            +                    SP P      P    R+   + +AT + V   +S     
Sbjct: 463  VKALTPRTTFLARQRQKI*SDSPSP*-----PWQLPRL---LPLAT-RVVRKISSL---- 603

Query: 2201 VIATANLSRRAIADMLRACKEAAFHPEVAPDVRLRALHYGRECANGYLELLDHVLLTLQK 2260
                  L R+ I ++    K  A       +++ RAL+ GR  A  Y ELL++V   + +
Sbjct: 604  ---PPTLGRKCIFELFGVIK-GAAATAETAEIKKRALNAGRSAAMTYKELLENVHQVVLR 771

Query: 2261 PNPDLKQQLTGHSKRVAGSVTELIQAAEAMKGTEWVDPEDPTVIXXXXXXXXXXXXXXXX 2320
            P  + +Q L   S++VA +VTEL+Q+AE +KGT+WVDP+DPTVI                
Sbjct: 772  PTQEGRQNLALVSRKVANAVTELVQSAEVIKGTDWVDPDDPTVIAENELLSAASSIEAAA 951

Query: 2321 XXXXXXXPRAKPKEADESLNFEEQILEXXXXXXXXXXXXXXXXXXXQRELVAQGKVGA-I 2379
                   PR   K+ADESLNF+EQILE                   QRELVAQGKV +  
Sbjct: 952  KKLSQLKPRQAAKKADESLNFDEQILEAAKSIAAATAALVKSASAAQRELVAQGKVSSTF 1131

Query: 2380 PANALD-DGQWSQGLISAARMVAAATNNLCEAANAAVQGHASQEKLISSAKQVAASTAQL 2438
              +A+D DGQWSQGLISAARMVAAAT++LCEAANA VQGHAS+EKLI+SAK+VA STAQL
Sbjct: 1132 TRHAVDEDGQWSQGLISAARMVAAATHSLCEAANAMVQGHASEEKLIASAKEVAGSTAQL 1311

Query: 2439 LVACKVKADQDSEAMKRLQAAGNAVKRASDNLVKAAQKAAAFEDQENETVVVKEKMVGGI 2498
            L+ACKVKAD  S AM+RLQAAGNAVKRAS+ LV+AAQ+    +++E E++ V ++MVGGI
Sbjct: 1312 LMACKVKADPGSVAMQRLQAAGNAVKRASEALVRAAQQERDVQEEE-ESLTVNKRMVGGI 1488

Query: 2499 AQ 2500
            AQ
Sbjct: 1489 AQ 1494

 Score = 52.8 bits (125), Expect(2) = e-119,   Method: Compositional matrix adjust.
 Identities = 26/32 (81%), Positives = 26/32 (81%)
 Frame = +2

Query: 2003 TLNREGAETFADHREGILKTAKVLVEDTKVLV 2034
            TLN EG ETFAD RE ILKTAK LVEDTK LV
Sbjct: 2    TLNPEGDETFADQRENILKTAKALVEDTKTLV 97

 Score = 32.3 bits (72), Expect = 2.2,   Method: Compositional matrix adjust.
 Identities = 23/66 (34%), Positives = 36/66 (54%)
 Frame = +1

Query: 1479 QSLGEPGCTQAQVLSAATIVAKHTSALCNSCRLASARTANPTAKRQFVQSAKEVANSTAN 1538
             ++ E G     ++SAA +VA  T +LC +   A+A      ++ + + SAKEVA STA 
Sbjct: 1138 HAVDEDGQWSQGLISAARMVAAATHSLCEA---ANAMVQGHASEEKLIASAKEVAGSTAQ 1308

Query: 1539 LVKTIK 1544
            L+   K
Sbjct: 1309 LLMACK 1326

 Score = 30.8 bits (68), Expect = 6.6,   Method: Compositional matrix adjust.
 Identities = 26/92 (28%), Positives = 45/92 (48%), Gaps = 2/92 (2%)
 Frame = +1

Query: 1467 FARANQAIQMACQSLGEPGCTQAQVL--SAATIVAKHTSALCNSCRLASARTANPTAKRQ 1524
              R    +++   SLG P   +AQVL  +A   VA   S L ++ + AS +  +  A   
Sbjct: 157  ITRLADVVKIGAGSLG-PEQPEAQVLLINAVKDVASALSDLISATKNASGKPVSDPAMLH 333

Query: 1525 FVQSAKEVANSTANLVKTIKALDGDFTEENRA 1556
               SAK +  +  +L+KT+K+++ +     RA
Sbjct: 334  LKDSAKVMVTNVTSLLKTVKSVEDEAVRGTRA 429
>30501
          Length = 638

 Score = 77.8 bits (190), Expect = 5e-14,   Method: Compositional matrix adjust.
 Identities = 55/143 (38%), Positives = 79/143 (55%), Gaps = 5/143 (3%)
 Frame = -1

Query: 2330 AKPKEADESLNFE--EQILEXXXXXXXXXXXXXXXXXXXQRELVAQGKVGAIPANAL--D 2385
            +K +E D  +  E  E+ILE                   Q+E+V+  K G   AN     
Sbjct: 503  SKSRENDNKIKLEVNEKILEACTSLMECIKILILKSRALQKEIVSSQK-GNASANEFYKR 327

Query: 2386 DGQWSQGLISAARMVAAATNNLCEAANAAVQGHASQE-KLISSAKQVAASTAQLLVACKV 2444
            + QWS GLISA++ VA A N L EAAN AV   + Q  +LI +A+++AA T QL++A KV
Sbjct: 326  NSQWSDGLISASKSVAKAANYLVEAANNAVNSDSXQNFELIVAAQEIAACTVQLVIASKV 147

Query: 2445 KADQDSEAMKRLQAAGNAVKRAS 2467
            KA+++SE +  L AA   V +A+
Sbjct: 146  KANRNSENLTNLTAASRNVTKAT 78
>08616
          Length = 2833

 Score = 61.2 bits (147), Expect = 5e-09,   Method: Composition-based stats.
 Identities = 43/140 (30%), Positives = 74/140 (52%), Gaps = 6/140 (4%)
 Frame = +2

Query: 263  KDFL-PKEYVKQKGE---RKIFQAHKNCGQMSEIEAKVRYVKLARSLKTYGVSFFLVKEK 318
            +DF+ P+ + K K +   ++I +AH N  +MS +EAK+ Y+K  +SL  +G+++F    +
Sbjct: 992  EDFIAPRFFKKIKSKAIVQRIMEAHANVREMSLMEAKMAYIKAWQSLPEFGITYF----R 1159

Query: 319  MKGKNKLVPRLLGITKECVMRVDEKTKEVIQEWSLTNIKRWAAS--PKSFTLDFGDYQDG 376
            +K  N     LLG+    V+R+D  T + I+ W    ++ W  +   +S  LDF D Q  
Sbjct: 1160 IKMANSKKEELLGVASNRVIRMDLNTGDSIKTWRYNLLQTWHVNWENESVILDFED-QKV 1336

Query: 377  YYSVQTTEGEQIAQLIAGYI 396
             +S      +   + I GYI
Sbjct: 1337 TFSPLECSCKTAHEFIGGYI 1396

 Score = 48.5 bits (114), Expect = 4e-05,   Method: Composition-based stats.
 Identities = 28/79 (35%), Positives = 49/79 (62%), Gaps = 3/79 (3%)
 Frame = +2

Query: 173 WLDHGRTLREQGVEEHETLLLRRKFF-YSDQNVDSRDPVQLNLLYVQARDDILNGSHPVS 231
           WLD  R+L EQGV+E++ ++L+ KF+ + D N    DP+++N +Y QA+  +++     +
Sbjct: 188 WLDSSRSLMEQGVQENDFIMLKFKFYNFYDLN-PKYDPIRINQIYEQAKWALISEEIDCT 364

Query: 232 FDKACEFAG--FQCQIQFG 248
            ++   FA   FQ Q+Q G
Sbjct: 365 EEEMMVFAALQFQSQLQSG 421
>17332
          Length = 473

 Score = 58.5 bits (140), Expect = 3e-08,   Method: Composition-based stats.
 Identities = 41/149 (27%), Positives = 70/149 (46%), Gaps = 13/149 (8%)
 Frame = +2

Query: 149 KTLLRDEKKMEKLKQKLHTDD-----------ELNWLDHGRTLREQ--GVEEHETLLLRR 195
           K +L  EK  E L   LH  D           + +WLD  ++L  Q  G +    L    
Sbjct: 41  KGILLQEKVCELLN--LHEKDYFGLRFIDASGQTHWLDGNKSLSSQLKGCQTPHKLYFGV 214

Query: 196 KFFYSDQNVDSRDPVQLNLLYVQARDDILNGSHPVSFDKACEFAGFQCQIQFGPHNEQKH 255
           KF+ +D     R+ +   L ++Q + DIL G  PV+FD+A E   +  Q + G  + ++H
Sbjct: 215 KFYAADP-CKLREEITRYLFFLQVKQDILQGRLPVTFDEASELCAYAVQSELGDFDPRQH 391

Query: 256 KAGFLDLKDFLPKEYVKQKGERKIFQAHK 284
             G++    F+P +   ++ ER++   H+
Sbjct: 392 TDGYVSEFCFIPNQ--TEELERRVAGLHR 472
>17228
          Length = 487

 Score = 37.4 bits (85), Expect = 0.077,   Method: Composition-based stats.
 Identities = 27/109 (24%), Positives = 52/109 (47%), Gaps = 5/109 (4%)
 Frame = +3

Query: 216 YVQARDDILNGSHPVSFDKACEFAGFQCQIQFGPHNEQKHKAGFLDLKD-FLPKEYVK-- 272
           + Q   + L G H V+ ++A + A    +++F    +  H   F D+    LP+ + +  
Sbjct: 132 FPQEVPNFLRGYHKVTGEEAVKMAALLYRVRFS--QDATHFTKFSDIAPAILPRGFPETG 305

Query: 273 --QKGERKIFQAHKNCGQMSEIEAKVRYVKLARSLKTYGVSFFLVKEKM 319
                ++ +   +KN    S    + R++++A S  TYG  FF VK++M
Sbjct: 306 LLDDVKKAVEAEYKNSTGSSPDSVRERFLQMAVSWPTYGCVFFEVKQRM 452
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|82802064|ref|XP_284175.5| PREDICTED: filamin C, gamma
isoform 1 [Mus musculus]
         (2726 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

13043                                                                 427   e-119
16231                                                                 251   6e-83
17351                                                                 258   3e-68
29446                                                                 204   5e-52
19277                                                                 180   4e-51
21436                                                                 147   5e-35
27230                                                                  75   1e-25
19002                                                                 101   4e-21
05081                                                                  88   6e-17
29755                                                                  64   1e-09
19147                                                                  63   2e-09
19154                                                                  62   4e-09
35059                                                                  57   1e-07
09100                                                                  53   2e-06
17613                                                                  53   2e-06
04951                                                                  50   2e-05
09711                                                                  49   3e-05
32088                                                                  40   0.015
18202                                                                  34   0.64 
02928                                                                  34   0.70 
31031                                                                  32   4.5  
>13043
          Length = 1574

 Score =  427 bits (1098), Expect = e-119,   Method: Compositional matrix adjust.
 Identities = 239/534 (44%), Positives = 315/534 (58%), Gaps = 2/534 (0%)
 Frame = +3

Query: 1391 PSEAKMSCKDNKDGSCTVEYIPFTPGDYDVNITFGGQPIPGSPFRXXXXXXXXXXXXXCS 1450
            P EAKM C DN+DG+C VEY P  PG YD+++ FG +PI  SPF              C 
Sbjct: 36   PVEAKMKCDDNRDGTCRVEYYPTKPGKYDISVLFGDKPIKDSPFSVKIQNPVDASKVKCY 215

Query: 1451 GPGL-GTGVRARVPQTFTVDCSQAGRAPLQVAVLGP-TGVAEPVEVRDNGDGTHTVHYTP 1508
            GPGL  + V A +P  FTVD   AG APL V    P +G  +  E+    +G +   Y P
Sbjct: 216  GPGLDASEVAANLPAVFTVDARDAGEAPLDVTFTDPLSGAQQEAEIVPVEEGLYQATYMP 395

Query: 1509 ATDGPYTVAVKYADQEVPRSPFKIKVLPSHDASKVRASGPGLNASGIPASLPVEFTIDAR 1568
              +G   V VKY  + VP SPF ++VLP  D SKV+ SGPG+  S +PASLP +FT+D R
Sbjct: 396  RAEGKCKVDVKYGGKPVPNSPFHMQVLPGVDPSKVKVSGPGVRRS-VPASLPAQFTVDTR 572

Query: 1569 DAGQGLLTVQILDPEGKPKKANIRDNGDGTYTVSYLPDMSGRYTITIKYGGDEIPYSPFR 1628
            DAG   L   +  P+G   K   ++N DGTY V Y P+  G Y I +KY G ++P SPF 
Sbjct: 573  DAGVADLECMVQRPDGSFIKPYFQNNEDGTYDVIYTPEDLGVYDIIVKYDGQDVPRSPFN 752

Query: 1629 IHALPTGDASKCLVTVSIGGHGLGACLGPRIQIGEETVITVDAKAAGKGKVTCTVSTPDG 1688
            + A P GDAS+C +T   G   +       I I +ETVITVDA  AGKG VTC + +P G
Sbjct: 753  VEATPLGDASQCRIT--DGAERV-------IPIEKETVITVDAADAGKGSVTCRIRSPSG 905

Query: 1689 AELDVDVVENHDGTFDIYYTAPEPGKYVITIRFGGEHIPNSPFHVLACDPLPHVEEPAEM 1748
            +++D+D+V+  DGTF I +     G+Y+I I+FGG  +P+  +   A   +P  +E  + 
Sbjct: 906  SDIDIDIVDQGDGTFTISFIPQYAGEYIIEIKFGGNFVPDGQYTAEA---VPE-DEYEKY 1073

Query: 1749 LQMRQPYAPLRPGTCPTHWATXXXXXXXXXLESMLRPFNLVIPFTVQKGELTGEVRMPSG 1808
            LQ R               A             + +P +   P       ++  V MPSG
Sbjct: 1074 LQSRV--------VDDLIVADQVDQVNAAPGSGLYQPVDFQFPVGPIFNFVSASVIMPSG 1229

Query: 1809 KTARPNITDNKDGTITVRYAPTEKGLHQMGIKYDGNHIPGSPLQFYVDAINSRHVSAYGP 1868
            KT+ P I DN+DGT+TVRY PTE GLH++ +KY+   I GSP  F+VD++NS +V+AYGP
Sbjct: 1230 KTSYPKIEDNRDGTVTVRYQPTETGLHELHVKYNNECIQGSPFFFHVDSVNSGYVTAYGP 1409

Query: 1869 GLSHGMVNKPATFTIVTKDAGEGGLSLAVEGPSKAEITCKDNKDGTCTVSYLPT 1922
            GLSHG+V +PA FTI TK+AG GGL+LAVEGPSK EI C DN+DGTC VSYLP+
Sbjct: 1410 GLSHGVVYEPAVFTINTKEAGAGGLALAVEGPSKTEIKCVDNQDGTCNVSYLPS 1571

 Score =  251 bits (641), Expect = 3e-66,   Method: Compositional matrix adjust.
 Identities = 181/541 (33%), Positives = 269/541 (49%), Gaps = 18/541 (3%)
 Frame = +3

Query: 603  GTLGFSIEGPSQAKIECDDKGDGSCDVRYWPTEPGEYAVHVICDDEDIRDSPFIAHIQPA 662
            G LG  IEGP +AK++CDD  DG+C V Y+PT+PG+Y + V+  D+ I+DSPF   IQ  
Sbjct: 9    GGLGLGIEGPVEAKMKCDDNRDGTCRVEYYPTKPGKYDISVLFGDKPIKDSPFSVKIQ-N 185

Query: 663  PPDCFPDKVKAFGPGLEPTGCIVDRPAEFTIDARAAGKGDLKLYAQD-ADGCPIDIKVIP 721
            P D    KVK +GPGL+ +    + PA FT+DAR AG+  L +   D   G   + +++P
Sbjct: 186  PVDA--SKVKCYGPGLDASEVAANLPAVFTVDARDAGEAPLDVTFTDPLSGAQQEAEIVP 359

Query: 722  NGDGTFRCSYVPTKPIKHTIIVSWGGVNVPKSPFRVNVGEGSHPERVKVYGPGVEKTGLK 781
              +G ++ +Y+P    K  + V +GG  VP SPF + V  G  P +VKV GPGV ++ + 
Sbjct: 360  VEEGLYQATYMPRAEGKCKVDVKYGGKPVPNSPFHMQVLPGVDPSKVKVSGPGVRRS-VP 536

Query: 782  ANEPTYFTVDCSEAGQGDVSIGIKCAPGVVGPVEAXXXXXXXXXXXXTFTVKYTPPGAGH 841
            A+ P  FTVD  +AG  D    ++C   V  P  +            T+ V YTP   G 
Sbjct: 537  ASLPAQFTVDTRDAGVAD----LECM--VQRPDGSFIKPYFQNNEDGTYDVIYTPEDLGV 698

Query: 842  YTIMVLFANQEIPASPFHIKVDPSHDASKVKAEGPGLSRTGVEVGKPTHFTVLTKGAGKA 901
            Y I+V +  Q++P SPF+++  P  DAS+ +    G  R  + + K T  TV    AGK 
Sbjct: 699  YDIIVKYDGQDVPRSPFNVEATPLGDASQCRITD-GAERV-IPIEKETVITVDAADAGKG 872

Query: 902  KLDVHFAGAAKGEAVRDFEIIDNHDYSYTVKYTAVQQGNMAVTVTYGGDPVPKSPFVVNV 961
             +       +  +   D +I+D  D ++T+ +     G   + + +GG+ VP   +    
Sbjct: 873  SVTCRIRSPSGSDI--DIDIVDQGDGTFTISFIPQYAGEYIIEIKFGGNFVPDGQYTAEA 1046

Query: 962  APPLDLSKVKVQGLNSKVA---VGQEQAFSVNTRGAGGQGQ--------------LDVRM 1004
             P  +  K     L S+V    +  +Q   VN     G  Q              +   +
Sbjct: 1047 VPEDEYEKY----LQSRVVDDLIVADQVDQVNAAPGSGLYQPVDFQFPVGPIFNFVSASV 1214

Query: 1005 TSPSRRPIPCKLEPGGGAEAQAVRYMPPEEGPYKVDITYDGHPVPGSPFAVEGVLPPDPS 1064
              PS +    K+E         VRY P E G +++ + Y+   + GSPF    V   +  
Sbjct: 1215 IMPSGKTSYPKIEDNRDGTV-TVRYQPTETGLHELHVKYNNECIQGSPFFFH-VDSVNSG 1388

Query: 1065 KVCAYGPGLKGGLVGTPAPFSIDTKXXXXXXXXXXVEGPCEAKIECQDNGDGSCAVSYLP 1124
             V AYGPGL  G+V  PA F+I+TK          VEGP + +I+C DN DG+C VSYLP
Sbjct: 1389 YVTAYGPGLSHGVVYEPAVFTINTKEAGAGGLALAVEGPSKTEIKCVDNQDGTCNVSYLP 1568

Query: 1125 T 1125
            +
Sbjct: 1569 S 1571

 Score =  235 bits (600), Expect = 2e-61,   Method: Compositional matrix adjust.
 Identities = 182/537 (33%), Positives = 250/537 (46%), Gaps = 29/537 (5%)
 Frame = +3

Query: 1100 VEGPCEAKIECQDNGDGSCAVSYLPTEPGEYTINILFAEAHIPGSPFKATIQPVFDPSKV 1159
            +EGP EAK++C DN DG+C V Y PT+PG+Y I++LF +  I  SPF   IQ   D SKV
Sbjct: 27   IEGPVEAKMKCDDNRDGTCRVEYYPTKPGKYDISVLFGDKPIKDSPFSVKIQNPVDASKV 206

Query: 1160 RASGPGLERGK--AGEAATFTVDCSEAGEAELTIEILSD-AGVKAEVLIQNNADGTYHIT 1216
            +  GPGL+  +  A   A FTVD  +AGEA L +      +G + E  I    +G Y  T
Sbjct: 207  KCYGPGLDASEVAANLPAVFTVDARDAGEAPLDVTFTDPLSGAQQEAEIVPVEEGLYQAT 386

Query: 1217 YSPAFPGTYTITIKYGGHPIPKFPTRVHVQPAVDTSGIKVSGPGVEPHGVLREVTTEFTV 1276
            Y P   G   + +KYGG P+P  P  + V P VD S +KVSGPGV    V   +  +FTV
Sbjct: 387  YMPRAEGKCKVDVKYGGKPVPNSPFHMQVLPGVDPSKVKVSGPGVR-RSVPASLPAQFTV 563

Query: 1277 DARSLTATGGNHVTARVLNPSGAKTDTYVTDNGDGTYRVQYTAYEEGVHLVEVLYDEVAV 1336
            D R     G   +   V  P G+    Y  +N DGTY V YT  + GV+ + V YD   V
Sbjct: 564  DTRD---AGVADLECMVQRPDGSFIKPYFQNNEDGTYDVIYTPEDLGVYDIIVKYDGQDV 734

Query: 1337 PKSPFRVGVTEGCDPTRVRAFGPGLEGGLVNKANRFTVXXXXXXXXXXXXXXXXP--SEA 1394
            P+SPF V  T   D ++ R          + K    TV                P  S+ 
Sbjct: 735  PRSPFNVEATPLGDASQCRITDGAERVIPIEKETVITVDAADAGKGSVTCRIRSPSGSDI 914

Query: 1395 KMSCKDNKDGSCTVEYIPFTPGDYDVNITFGGQPIPGSPFRXXXXXXXXXXXXXCSGPGL 1454
             +   D  DG+ T+ +IP   G+Y + I FGG  +P   +                    
Sbjct: 915  DIDIVDQGDGTFTISFIPQYAGEYIIEIKFGGNFVPDGQYTAEAVPEDEYEKY------- 1073

Query: 1455 GTGVRARVPQTFTV--DCSQAGRAP--------------------LQVAVLGPTGVAEPV 1492
               +++RV     V     Q   AP                    +  +V+ P+G     
Sbjct: 1074 ---LQSRVVDDLIVADQVDQVNAAPGSGLYQPVDFQFPVGPIFNFVSASVIMPSGKTSYP 1244

Query: 1493 EVRDNGDGTHTVHYTPATDGPYTVAVKYADQEVPRSPFKIKVLPSHDASKVRASGPGLNA 1552
            ++ DN DGT TV Y P   G + + VKY ++ +  SPF   V  S ++  V A GPGL+ 
Sbjct: 1245 KIEDNRDGTVTVRYQPTETGLHELHVKYNNECIQGSPFFFHV-DSVNSGYVTAYGPGLSH 1421

Query: 1553 SGIPASLPVEFTIDARDAGQGLLTVQILDPEGKPKKANIR--DNGDGTYTVSYLPDM 1607
              +    P  FTI+ ++AG G L + +   EG P K  I+  DN DGT  VSYLP +
Sbjct: 1422 GVV--YEPAVFTINTKEAGAGGLALAV---EG-PSKTEIKCVDNQDGTCNVSYLPSV 1574

 Score =  211 bits (537), Expect = 3e-54,   Method: Compositional matrix adjust.
 Identities = 167/515 (32%), Positives = 244/515 (47%), Gaps = 25/515 (4%)
 Frame = +3

Query: 923  DNHDYSYTVKYTAVQQGNMAVTVTYGGDPVPKSPFVVNVAPPLDLSKVKVQGLN---SKV 979
            DN D +  V+Y   + G   ++V +G  P+  SPF V +  P+D SKVK  G     S+V
Sbjct: 63   DNRDGTCRVEYYPTKPGKYDISVLFGDKPIKDSPFSVKIQNPVDASKVKCYGPGLDASEV 242

Query: 980  AVGQEQAFSVNTRGAGGQGQLDVRMTSP-SRRPIPCKLEPGGGAEAQAVRYMPPEEGPYK 1038
            A      F+V+ R AG +  LDV  T P S      ++ P      QA  YMP  EG  K
Sbjct: 243  AANLPAVFTVDARDAG-EAPLDVTFTDPLSGAQQEAEIVPVEEGLYQAT-YMPRAEGKCK 416

Query: 1039 VDITYDGHPVPGSPFAVEGVLPPDPSKVCAYGPGLKGGL-VGTPAPFSIDTKXXXXXXXX 1097
            VD+ Y G PVP SPF ++ +   DPSKV   GPG++  +    PA F++DT+        
Sbjct: 417  VDVKYGGKPVPNSPFHMQVLPGVDPSKVKVSGPGVRRSVPASLPAQFTVDTRDAGVADLE 596

Query: 1098 XXVEGPCEAKIE--CQDNGDGSCAVSYLPTEPGEYTINILFAEAHIPGSPFKATIQPVFD 1155
              V+ P  + I+   Q+N DG+  V Y P + G Y I + +    +P SPF     P+ D
Sbjct: 597  CMVQRPDGSFIKPYFQNNEDGTYDVIYTPEDLGVYDIIVKYDGQDVPRSPFNVEATPLGD 776

Query: 1156 PSKVRASGPGLERGKAGEAAT-FTVDCSEAGEAELTIEILSDAGVKAEVLIQNNADGTYH 1214
             S+ R +  G ER    E  T  TVD ++AG+  +T  I S +G   ++ I +  DGT+ 
Sbjct: 777  ASQCRITD-GAERVIPIEKETVITVDAADAGKGSVTCRIRSPSGSDIDIDIVDQGDGTFT 953

Query: 1215 ITYSPAFPGTYTITIKYGGHPIPKFPTRVHVQP-----------------AVDTSGIKVS 1257
            I++ P + G Y I IK+GG+ +P         P                   D      +
Sbjct: 954  ISFIPQYAGEYIIEIKFGGNFVPDGQYTAEAVPEDEYEKYLQSRVVDDLIVADQVDQVNA 1133

Query: 1258 GPGVEPHGVLREVTTEFTVDARSLTATGGNHVTARVLNPSGAKTDTYVTDNGDGTYRVQY 1317
             PG    G+ + V  +F V          N V+A V+ PSG  +   + DN DGT  V+Y
Sbjct: 1134 APG---SGLYQPVDFQFPVGPIF------NFVSASVIMPSGKTSYPKIEDNRDGTVTVRY 1286

Query: 1318 TAYEEGVHLVEVLYDEVAVPKSPFRVGVTEGCDPTRVRAFGPGLEGGLVNKANRFTVXXX 1377
               E G+H + V Y+   +  SPF   V +  +   V A+GPGL  G+V +   FT+   
Sbjct: 1287 QPTETGLHELHVKYNNECIQGSPFFFHV-DSVNSGYVTAYGPGLSHGVVYEPAVFTINTK 1463

Query: 1378 XXXXXXXXXXXXXPSEAKMSCKDNKDGSCTVEYIP 1412
                         PS+ ++ C DN+DG+C V Y+P
Sbjct: 1464 EAGAGGLALAVEGPSKTEIKCVDNQDGTCNVSYLP 1568

 Score =  202 bits (513), Expect = 2e-51,   Method: Compositional matrix adjust.
 Identities = 153/542 (28%), Positives = 241/542 (44%), Gaps = 25/542 (4%)
 Frame = +3

Query: 1588 KANIRDNGDGTYTVSYLPDMSGRYTITIKYGGDEIPYSPFRIHALPTGDASKCLVTVSIG 1647
            K    DN DGT  V Y P   G+Y I++ +G   I  SPF +      DASK    V   
Sbjct: 48   KMKCDDNRDGTCRVEYYPTKPGKYDISVLFGDKPIKDSPFSVKIQNPVDASK----VKCY 215

Query: 1648 GHGLGACLGPRIQIGEETVITVDAKAAGKGKVTCTVSTP-DGAELDVDVVENHDGTFDIY 1706
            G GL A     +      V TVDA+ AG+  +  T + P  GA+ + ++V   +G +   
Sbjct: 216  GPGLDAS---EVAANLPAVFTVDARDAGEAPLDVTFTDPLSGAQQEAEIVPVEEGLYQAT 386

Query: 1707 YTAPEPGKYVITIRFGGEHIPNSPFHVLACDPLPHVEEPAEMLQMRQPYAPLRPGTCPTH 1766
            Y     GK  + +++GG+ +PNSPFH+     LP V+ P+++           P + P  
Sbjct: 387  YMPRAEGKCKVDVKYGGKPVPNSPFHMQV---LPGVD-PSKVKVSGPGVRRSVPASLPAQ 554

Query: 1767 WATXXXXXXXXXLESMLRPFNLVIPFTVQKGELTGEVRMPSGKTARPNITDNKDGTITVR 1826
            +           LE M                    V+ P G   +P   +N+DGT  V 
Sbjct: 555  FTVDTRDAGVADLECM--------------------VQRPDGSFIKPYFQNNEDGTYDVI 674

Query: 1827 YAPTEKGLHQMGIKYDGNHIPGSPLQFYVDAINSRHVSAYGPGLSHGM-VNKPATFTIVT 1885
            Y P + G++ + +KYDG  +P SP       +          G    + + K    T+  
Sbjct: 675  YTPEDLGVYDIIVKYDGQDVPRSPFNVEATPLGDASQCRITDGAERVIPIEKETVITVDA 854

Query: 1886 KDAGEGGLSLAVEGPSKAEITCK--DNKDGTCTVSYLPTAPGDYSIIVRFDDKHIPGSPF 1943
             DAG+G ++  +  PS ++I     D  DGT T+S++P   G+Y I ++F    +P   +
Sbjct: 855  ADAGKGSVTCRIRSPSGSDIDIDIVDQGDGTFTISFIPQYAGEYIIEIKFGGNFVPDGQY 1034

Query: 1944 TAKITGDDSM----------------RTSQLNV----GTSTDVSLKITEGDLSQL-TASI 1982
            TA+   +D                  +  Q+N     G    V  +   G +    +AS+
Sbjct: 1035 TAEAVPEDEYEKYLQSRVVDDLIVADQVDQVNAAPGSGLYQPVDFQFPVGPIFNFVSASV 1214

Query: 1983 RAPSGNEEPCLLKRLPNRHIGISFTPKEVGEHVVSVRKSGKHVTNSPFKILVGPSEIGDA 2042
              PSG      ++   +  + + + P E G H + V+ + + +  SPF   V     G  
Sbjct: 1215 IMPSGKTSYPKIEDNRDGTVTVRYQPTETGLHELHVKYNNECIQGSPFFFHVDSVNSG-- 1388

Query: 2043 SKVRVWGKGLSEGQTFQVAEFIVDTRNAGYGGLGLSIEGPSKVDINCEDMEDGTCKVTYC 2102
              V  +G GLS G  ++ A F ++T+ AG GGL L++EGPSK +I C D +DGTC V+Y 
Sbjct: 1389 -YVTAYGPGLSHGVVYEPAVFTINTKEAGAGGLALAVEGPSKTEIKCVDNQDGTCNVSYL 1565

Query: 2103 PT 2104
            P+
Sbjct: 1566 PS 1571

 Score =  191 bits (484), Expect = 5e-48,   Method: Compositional matrix adjust.
 Identities = 140/450 (31%), Positives = 208/450 (46%), Gaps = 25/450 (5%)
 Frame = +3

Query: 1307 DNGDGTYRVQYTAYEEGVHLVEVLYDEVAVPKSPFRVGVTEGCDPTRVRAFGPGLEGGLV 1366
            DN DGT RV+Y   + G + + VL+ +  +  SPF V +    D ++V+ +GPGL+   V
Sbjct: 63   DNRDGTCRVEYYPTKPGKYDISVLFGDKPIKDSPFSVKIQNPVDASKVKCYGPGLDASEV 242

Query: 1367 --NKANRFTVXXXXXXXXXXXXXXXXP---SEAKMSCKDNKDGSCTVEYIPFTPGDYDVN 1421
              N    FTV                P   ++ +      ++G     Y+P   G   V+
Sbjct: 243  AANLPAVFTVDARDAGEAPLDVTFTDPLSGAQQEAEIVPVEEGLYQATYMPRAEGKCKVD 422

Query: 1422 ITFGGQPIPGSPFRXXXXXXXXXXXXXCSGPGLGTGVRARVPQTFTVDCSQAGRAPLQVA 1481
            + +GG+P+P SPF               SGPG+   V A +P  FTVD   AG A L+  
Sbjct: 423  VKYGGKPVPNSPFHMQVLPGVDPSKVKVSGPGVRRSVPASLPAQFTVDTRDAGVADLECM 602

Query: 1482 VLGPTGVAEPVEVRDNGDGTHTVHYTPATDGPYTVAVKYADQEVPRSPFKIKVLPSHDAS 1541
            V  P G       ++N DGT+ V YTP   G Y + VKY  Q+VPRSPF ++  P  DAS
Sbjct: 603  VQRPDGSFIKPYFQNNEDGTYDVIYTPEDLGVYDIIVKYDGQDVPRSPFNVEATPLGDAS 782

Query: 1542 KVRASGPGLNASGIPASLPVE----FTIDARDAGQGLLTVQILDPEGKPKKANIRDNGDG 1597
            + R +       G    +P+E     T+DA DAG+G +T +I  P G     +I D GDG
Sbjct: 783  QCRIT------DGAERVIPIEKETVITVDAADAGKGSVTCRIRSPSGSDIDIDIVDQGDG 944

Query: 1598 TYTVSYLPDMSGRYTITIKYGGDEIPYSPFRIHALPTGDASKCLVTVSIGGHGLGACLGP 1657
            T+T+S++P  +G Y I IK+GG+ +P   +   A+P  +  K L +  +           
Sbjct: 945  TFTISFIPQYAGEYIIEIKFGGNFVPDGQYTAEAVPEDEYEKYLQSRVVDD--------- 1097

Query: 1658 RIQIGEETVITVDAKAAGKGK----------------VTCTVSTPDGAELDVDVVENHDG 1701
               I  + V  V+A A G G                 V+ +V  P G      + +N DG
Sbjct: 1098 --LIVADQVDQVNA-APGSGLYQPVDFQFPVGPIFNFVSASVIMPSGKTSYPKIEDNRDG 1268

Query: 1702 TFDIYYTAPEPGKYVITIRFGGEHIPNSPF 1731
            T  + Y   E G + + +++  E I  SPF
Sbjct: 1269 TVTVRYQPTETGLHELHVKYNNECIQGSPF 1358

 Score =  189 bits (479), Expect = 2e-47,   Method: Compositional matrix adjust.
 Identities = 142/532 (26%), Positives = 233/532 (43%), Gaps = 36/532 (6%)
 Frame = +3

Query: 2071 GYGGLGLSIEGPSKVDINCEDMEDGTCKVTYCPTEPGTYIINIKFADKHVPGSPFTVKVT 2130
            G GGLGL IEGP +  + C+D  DGTC+V Y PT+PG Y I++ F DK +  SPF+VK+ 
Sbjct: 3    GKGGLGLGIEGPVEAKMKCDDNRDGTCRVEYYPTKPGKYDISVLFGDKPIKDSPFSVKIQ 182

Query: 2131 G---------EGRMKESITRRRQAPSIATIGST------CDLNLKIPGNWFQMVSAQERL 2175
                       G   ++       P++ T+ +        D+    P +  Q  +    +
Sbjct: 183  NPVDASKVKCYGPGLDASEVAANLPAVFTVDARDAGEAPLDVTFTDPLSGAQQEAEIVPV 362

Query: 2176 TRTFTRSSHTYTRTERTEISKTRGGETKREVRVEESTQVGGDPFPA-VFGDFLGRERLGS 2234
                 ++++      + ++    GG+             G DP    V G  + R    S
Sbjct: 363  EEGLYQATYMPRAEGKCKVDVKYGGKPVPNSPFHMQVLPGVDPSKVKVSGPGVRRSVPAS 542

Query: 2235 FGSITRQQEGEASSQDMTAQVTSPSGKTEAAEIVEGEDSAYSVRFVPQEMGPHTVTVKYR 2294
              +       +A   D+   V  P G          ED  Y V + P+++G + + VKY 
Sbjct: 543  LPAQFTVDTRDAGVADLECMVQRPDGSFIKPYFQNNEDGTYDVIYTPEDLGVYDIIVKYD 722

Query: 2295 GQHVPGSPFQFTVGPLGEGGAHKVRAGGTGLERGVAGVPAE----FSIWTREAGAGGLSI 2350
            GQ VP SPF     PLG+    ++  G   +      +P E     ++   +AG G ++ 
Sbjct: 723  GQDVPRSPFNVEATPLGDASQCRITDGAERV------IPIEKETVITVDAADAGKGSVTC 884

Query: 2351 AVEGPSKAEIAFE--DRKDGSCGVSYVVQEPGDYEVSIKFNDEHIPDSPFVVPVASLSDD 2408
             +  PS ++I  +  D+ DG+  +S++ Q  G+Y + IKF    +PD  +        + 
Sbjct: 885  RIRSPSGSDIDIDIVDQGDGTFTISFIPQYAGEYIIEIKFGGNFVPDGQYTAEAVPEDEY 1064

Query: 2409 ARRLTVTSLQET-------------GLKVNQPASFAVQLNGARGVIDARVHTPSGAVEEC 2455
             + L    + +              G  + QP  F   +      + A V  PSG     
Sbjct: 1065 EKYLQSRVVDDLIVADQVDQVNAAPGSGLYQPVDFQFPVGPIFNFVSASVIMPSGKTSYP 1244

Query: 2456 YVSELDSDKHTIRFIPHENGVHSIDVKFNGAHIPGSPFKIRVGEQSQAGDPGLVSAYGPG 2515
             + +      T+R+ P E G+H + VK+N   I GSPF   V     + + G V+AYGPG
Sbjct: 1245 KIEDNRDGTVTVRYQPTETGLHELHVKYNNECIQGSPFFFHV----DSVNSGYVTAYGPG 1412

Query: 2516 LEGGTTGVSSEFIVNTQNAGSGALSVTIDGPSKVQLDCRECPEGHV-VTYTP 2566
            L  G     + F +NT+ AG+G L++ ++GPSK ++ C +  +G   V+Y P
Sbjct: 1413 LSHGVVYEPAVFTINTKEAGAGGLALAVEGPSKTEIKCVDNQDGTCNVSYLP 1568

 Score =  159 bits (403), Expect = 1e-38,   Method: Compositional matrix adjust.
 Identities = 142/490 (28%), Positives = 222/490 (45%), Gaps = 22/490 (4%)
 Frame = +3

Query: 267 APVRSKQLNP---KKAIAYGPGIEPQGNTVLQPAHFTVQTVDAGVGEVLVYIEDP-EGHT 322
           +P   K  NP    K   YGPG++        PA FTV   DAG   + V   DP  G  
Sbjct: 159 SPFSVKIQNPVDASKVKCYGPGLDASEVAANLPAVFTVDARDAGEAPLDVTFTDPLSGAQ 338

Query: 323 EEAKVVPNNDKDRTYAVSYVPKVAGLHKVTVLFAGQNIERSPFEVNVGMALGDANKVSAR 382
           +EA++VP   ++  Y  +Y+P+  G  KV V + G+ +  SPF + V   + D +KV   
Sbjct: 339 QEAEIVPV--EEGLYQATYMPRAEGKCKVDVKYGGKPVPNSPFHMQVLPGV-DPSKVKVS 509

Query: 383 GPGLEPVGNVANKPTYFDIYTAGAGTGDVAVVIVDPQGRRDTVEVALEDKGDNTFRCTYR 442
           GPG+      A+ P  F + T  AG  D+  ++  P G    ++   ++  D T+   Y 
Sbjct: 510 GPGVR-RSVPASLPAQFTVDTRDAGVADLECMVQRPDGS--FIKPYFQNNEDGTYDVIYT 680

Query: 443 PVMEGPHTVHVAFAGAPITRSPFPVHVAEACNPNACRASGRGLQPKGVRVKEVADFKVFT 502
           P   G + + V + G  + RSPF V      + + CR +      + + +++     V  
Sbjct: 681 PEDLGVYDIIVKYDGQDVPRSPFNVEATPLGDASQCRITDGA--ERVIPIEKETVITVDA 854

Query: 503 KGAGSGELKVTVKGPKGTEEPVKVREAGDGVFECEYYPVVPGKYVVTITWGGYAIPRSPF 562
             AG G +   ++ P G++  + + + GDG F   + P   G+Y++ I +GG  +P   +
Sbjct: 855 ADAGKGSVTCRIRSPSGSDIDIDIVDQGDGTFTISFIPQYAGEYIIEIKFGGNFVPDGQY 1034

Query: 563 EVQVSPEAGAQKV---RAWGPGLETGQVG-----------KSADFVVEAIGTEVGTLGFS 608
             +  PE   +K    R     +   QV            +  DF    +G     +  S
Sbjct: 1035TAEAVPEDEYEKYLQSRVVDDLIVADQVDQVNAAPGSGLYQPVDFQF-PVGPIFNFVSAS 1211

Query: 609 IEGP----SQAKIECDDKGDGSCDVRYWPTEPGEYAVHVICDDEDIRDSPFIAHIQPAPP 664
           +  P    S  KIE  D  DG+  VRY PTE G + +HV  ++E I+ SPF  H+     
Sbjct: 1212VIMPSGKTSYPKIE--DNRDGTVTVRYQPTETGLHELHVKYNNECIQGSPFFFHVD---- 1373

Query: 665 DCFPDKVKAFGPGLEPTGCIVDRPAEFTIDARAAGKGDLKLYAQDADGCPIDIKVIPNGD 724
                 V A+GPGL  +  +V  PA FTI+ + AG G L L  +       +IK + N D
Sbjct: 1374SVNSGYVTAYGPGL--SHGVVYEPAVFTINTKEAGAGGLALAVEGP--SKTEIKCVDNQD 1541

Query: 725 GTFRCSYVPT 734
           GT   SY+P+
Sbjct: 1542GTCNVSYLPS 1571

 Score =  154 bits (388), Expect = 6e-37,   Method: Compositional matrix adjust.
 Identities = 137/510 (26%), Positives = 225/510 (44%), Gaps = 28/510 (5%)
 Frame = +3

Query: 324 EAKVVPNNDKDRTYAVSYVPKVAGLHKVTVLFAGQNIERSPFEVNVGMALGDANKVSARG 383
           EAK+  ++++D T  V Y P   G + ++VLF  + I+ SPF V +   + DA+KV   G
Sbjct: 42  EAKMKCDDNRDGTCRVEYYPTKPGKYDISVLFGDKPIKDSPFSVKIQNPV-DASKVKCYG 218

Query: 384 PGLEPVGNVANKPTYFDIYTAGAGTGDVAVVIVDP-QGRRDTVEVALEDKGDNTFRCTYR 442
           PGL+     AN P  F +    AG   + V   DP  G +   E+   ++G   ++ TY 
Sbjct: 219 PGLDASEVAANLPAVFTVDARDAGEAPLDVTFTDPLSGAQQEAEIVPVEEG--LYQATYM 392

Query: 443 PVMEGPHTVHVAFAGAPITRSPFPVHVAEACNPNACRASGRGLQPKGVRVKEVADFKVFT 502
           P  EG   V V + G P+  SPF + V    +P+  + SG G++ + V     A F V T
Sbjct: 393 PRAEGKCKVDVKYGGKPVPNSPFHMQVLPGVDPSKVKVSGPGVR-RSVPASLPAQFTVDT 569

Query: 503 KGAGSGELKVTVKGPKGTEEPVKVREAGDGVFECEYYPVVPGKYVVTITWGGYAIPRSPF 562
           + AG  +L+  V+ P G+      +   DG ++  Y P   G Y + + + G  +PRSPF
Sbjct: 570 RDAGVADLECMVQRPDGSFIKPYFQNNEDGTYDVIYTPEDLGVYDIIVKYDGQDVPRSPF 749

Query: 563 EVQVSPEAGAQKVRAWGPGLETGQVGKSADFVVEAIGTEVGTLGFSIEGPSQAKIECD-- 620
            V+ +P   A + R          + K     V+A     G++   I  PS + I+ D  
Sbjct: 750 NVEATPLGDASQCRITDGAERVIPIEKETVITVDAADAGKGSVTCRIRSPSGSDIDIDIV 929

Query: 621 DKGDGSCDVRYWPTEPGEYAVHVICDDEDIRDSPFIAHIQPAPPDCFPDKVKAFGPGLEP 680
           D+GDG+  + + P   GEY + +      + D  + A  +  P D +   ++        
Sbjct: 930 DQGDGTFTISFIPQYAGEYIIEIKFGGNFVPDGQYTA--EAVPEDEYEKYLQ-------- 1079

Query: 681 TGCIVDRPAEFTIDARAAGKGDLKLYAQDADGCPIDIK--------------VIPNG--- 723
           +  + D      +D   A  G   LY       P+D +              ++P+G   
Sbjct: 1080SRVVDDLIVADQVDQVNAAPGS-GLYQ------PVDFQFPVGPIFNFVSASVIMPSGKTS 1238

Query: 724 --------DGTFRCSYVPTKPIKHTIIVSWGGVNVPKSPFRVNVGEGSHPERVKVYGPGV 775
                   DGT    Y PT+   H + V +    +  SPF  +V +  +   V  YGPG+
Sbjct: 1239YPKIEDNRDGTVTVRYQPTETGLHELHVKYNNECIQGSPFFFHV-DSVNSGYVTAYGPGL 1415

Query: 776 EKTGLKANEPTYFTVDCSEAGQGDVSIGIK 805
               +   EP  FT++  EAG G +++ ++
Sbjct: 1416SHGVVY--EPAVFTINTKEAGAGGLALAVE 1499

 Score =  145 bits (365), Expect = 3e-34,   Method: Compositional matrix adjust.
 Identities = 154/546 (28%), Positives = 230/546 (42%), Gaps = 20/546 (3%)
 Frame = +3

Query: 506  GSGELKVTVKGPKGTEEPVKVREAGDGVFECEYYPVVPGKYVVTITWGGYAIPRSPFEVQ 565
            G G L + ++GP   E  +K  +  DG    EYYP  PGKY +++ +G   I  SPF V+
Sbjct: 3    GKGGLGLGIEGP--VEAKMKCDDNRDGTCRVEYYPTKPGKYDISVLFGDKPIKDSPFSVK 176

Query: 566  VSPEAGAQKVRAWGPGLETGQVGKS--ADFVVEAIGTEVGTLGFSIEGP---SQAKIECD 620
            +     A KV+ +GPGL+  +V  +  A F V+A       L  +   P   +Q + E  
Sbjct: 177  IQNPVDASKVKCYGPGLDASEVAANLPAVFTVDARDAGEAPLDVTFTDPLSGAQQEAEIV 356

Query: 621  DKGDGSCDVRYWPTEPGEYAVHVICDDEDIRDSPFIAHIQPAPPDCFPDKVKAFGPGLEP 680
               +G     Y P   G+  V V    + + +SPF  H+Q   P   P KVK  GPG+  
Sbjct: 357  PVEEGLYQATYMPRAEGKCKVDVKYGGKPVPNSPF--HMQ-VLPGVDPSKVKVSGPGVRR 527

Query: 681  TGCIVDRPAEFTIDARAAGKGDLKLYAQDADGCPIDIKVIPNGDGTFRCSYVPTKPIKHT 740
            +      PA+FT+D R AG  DL+   Q  DG  I      N DGT+   Y P     + 
Sbjct: 528  S-VPASLPAQFTVDTRDAGVADLECMVQRPDGSFIKPYFQNNEDGTYDVIYTPEDLGVYD 704

Query: 741  IIVSWGGVNVPKSPFRVNVGEGSHPERVKVYGPGVEKTGLKANEPTYFTVDCSEAGQGDV 800
            IIV + G +VP+SPF V         + ++   G E+  +   + T  TVD ++AG+G V
Sbjct: 705  IIVKYDGQDVPRSPFNVEATPLGDASQCRITD-GAERV-IPIEKETVITVDAADAGKGSV 878

Query: 801  SIGIKCAPGVVGPVEAXXXXXXXXXXXXTFTVKYTPPGAGHYTIMVLFANQEIPASPFHI 860
            +  I+   G      +            TFT+ + P  AG Y I + F    +P   +  
Sbjct: 879  TCRIRSPSG------SDIDIDIVDQGDGTFTISFIPQYAGEYIIEIKFGGNFVPDGQYTA 1040

Query: 861  KVDPSHDASKVKAEGPGLSRT--GVEVGKPTHFTVLTKGAGKAK-LDVHFAGAAKGEAVR 917
            +  P  +  K        SR    + V           G+G  + +D  F        V 
Sbjct: 1041 EAVPEDEYEKYLQ-----SRVVDDLIVADQVDQVNAAPGSGLYQPVDFQFPVGPIFNFVS 1205

Query: 918  DFEII-----------DNHDYSYTVKYTAVQQGNMAVTVTYGGDPVPKSPFVVNVAPPLD 966
               I+           DN D + TV+Y   + G   + V Y  + +  SPF  +V   ++
Sbjct: 1206 ASVIMPSGKTSYPKIEDNRDGTVTVRYQPTETGLHELHVKYNNECIQGSPFFFHVD-SVN 1382

Query: 967  LSKVKVQGLNSKVAVGQEQA-FSVNTRGAGGQGQLDVRMTSPSRRPIPCKLEPGGGAEAQ 1025
               V   G      V  E A F++NT+ AG  G L + +  PS+  I C     G     
Sbjct: 1383 SGYVTAYGPGLSHGVVYEPAVFTINTKEAGA-GGLALAVEGPSKTEIKCVDNQDGTCN-- 1553

Query: 1026 AVRYMP 1031
             V Y+P
Sbjct: 1554 -VSYLP 1568

 Score =  127 bits (318), Expect = 8e-29,   Method: Compositional matrix adjust.
 Identities = 90/256 (35%), Positives = 130/256 (50%), Gaps = 14/256 (5%)
 Frame = +3

Query: 1889 GEGGLSLAVEGPSKAEITCKDNKDGTCTVSYLPTAPGDYSIIVRFDDKHIPGSPFTAKIT 1948
            G+GGL L +EGP +A++ C DN+DGTC V Y PT PG Y I V F DK I  SPF+ KI 
Sbjct: 3    GKGGLGLGIEGPVEAKMKCDDNRDGTCRVEYYPTKPGKYDISVLFGDKPIKDSPFSVKIQ 182

Query: 1949 G--DDS--------MRTSQLNVGTSTDVSLKITEGDLSQLTASIRAP-SGNEEPCLLKRL 1997
               D S        +  S++        ++   +   + L  +   P SG ++   +  +
Sbjct: 183  NPVDASKVKCYGPGLDASEVAANLPAVFTVDARDAGEAPLDVTFTDPLSGAQQEAEIVPV 362

Query: 1998 PNRHIGISFTPKEVGEHVVSVRKSGKHVTNSPFKILVGPSEIGDASKVRVWGKGLSEGQT 2057
                   ++ P+  G+  V V+  GK V NSPF + V P    D SKV+V G G+     
Sbjct: 363  EEGLYQATYMPRAEGKCKVDVKYGGKPVPNSPFHMQVLPGV--DPSKVKVSGPGVRRSVP 536

Query: 2058 FQV-AEFIVDTRNAGYGGLGLSIEGP--SKVDINCEDMEDGTCKVTYCPTEPGTYIINIK 2114
              + A+F VDTR+AG   L   ++ P  S +    ++ EDGT  V Y P + G Y I +K
Sbjct: 537  ASLPAQFTVDTRDAGVADLECMVQRPDGSFIKPYFQNNEDGTYDVIYTPEDLGVYDIIVK 716

Query: 2115 FADKHVPGSPFTVKVT 2130
            +  + VP SPF V+ T
Sbjct: 717  YDGQDVPRSPFNVEAT 764

 Score =  125 bits (315), Expect = 2e-28,   Method: Compositional matrix adjust.
 Identities = 97/353 (27%), Positives = 157/353 (44%), Gaps = 21/353 (5%)
 Frame = +3

Query: 1811 ARPNITDNKDGTITVRYAPTEKGLHQMGIKYDGNHIPGSPLQFYV-DAINSRHVSAYGPG 1869
            A+    DN+DGT  V Y PT+ G + + + +    I  SP    + + +++  V  YGPG
Sbjct: 45   AKMKCDDNRDGTCRVEYYPTKPGKYDISVLFGDKPIKDSPFSVKIQNPVDASKVKCYGPG 224

Query: 1870 LSHGMV--NKPATFTIVTKDAGEGGLSLAVEGP---SKAEITCKDNKDGTCTVSYLPTAP 1924
            L    V  N PA FT+  +DAGE  L +    P   ++ E      ++G    +Y+P A 
Sbjct: 225  LDASEVAANLPAVFTVDARDAGEAPLDVTFTDPLSGAQQEAEIVPVEEGLYQATYMPRAE 404

Query: 1925 GDYSIIVRFDDKHIPGSPFTAKIT-GDDSMRTSQLNVGTSTDVSLKITEGDLSQLTASIR 1983
            G   + V++  K +P SPF  ++  G D  +      G    V   +     +Q T   R
Sbjct: 405  GKCKVDVKYGGKPVPNSPFHMQVLPGVDPSKVKVSGPGVRRSVPASLP----AQFTVDTR 572

Query: 1984 APSGNEEPCLLKR---------LPNRHIG---ISFTPKEVGEHVVSVRKSGKHVTNSPFK 2031
                 +  C+++R           N   G   + +TP+++G + + V+  G+ V  SPF 
Sbjct: 573  DAGVADLECMVQRPDGSFIKPYFQNNEDGTYDVIYTPEDLGVYDIIVKYDGQDVPRSPFN 752

Query: 2032 ILVGPSEIGDASKVRVWGKGLSEGQTFQVAEFIVDTRNAGYGGLGLSIEGPS--KVDINC 2089
            +   P  +GDAS+ R+           +     VD  +AG G +   I  PS   +DI+ 
Sbjct: 753  VEATP--LGDASQCRITDGAERVIPIEKETVITVDAADAGKGSVTCRIRSPSGSDIDIDI 926

Query: 2090 EDMEDGTCKVTYCPTEPGTYIINIKFADKHVPGSPFTVKVTGEGRMKESITRR 2142
             D  DGT  +++ P   G YII IKF    VP   +T +   E   ++ +  R
Sbjct: 927  VDQGDGTFTISFIPQYAGEYIIEIKFGGNFVPDGQYTAEAVPEDEYEKYLQSR 1085

 Score =  118 bits (295), Expect = 4e-26,   Method: Compositional matrix adjust.
 Identities = 99/381 (25%), Positives = 172/381 (45%), Gaps = 7/381 (1%)
 Frame = +3

Query: 2344 GAGGLSIAVEGPSKAEIAFEDRKDGSCGVSYVVQEPGDYEVSIKFNDEHIPDSPFVVPVA 2403
            G GGL + +EGP +A++  +D +DG+C V Y   +PG Y++S+ F D+ I DSPF V + 
Sbjct: 3    GKGGLGLGIEGPVEAKMKCDDNRDGTCRVEYYPTKPGKYDISVLFGDKPIKDSPFSVKIQ 182

Query: 2404 SLSDDAR-RLTVTSLQETGLKVNQPASFAVQLNGA-RGVIDARVHTP-SGAVEECYVSEL 2460
            +  D ++ +     L  + +  N PA F V    A    +D     P SGA +E  +  +
Sbjct: 183  NPVDASKVKCYGPGLDASEVAANLPAVFTVDARDAGEAPLDVTFTDPLSGAQQEAEIVPV 362

Query: 2461 DSDKHTIRFIPHENGVHSIDVKFNGAHIPGSPFKIRVGEQSQAGDPGLVSAYGPGLEGGT 2520
            +   +   ++P   G   +DVK+ G  +P SPF ++V       DP  V   GPG+    
Sbjct: 363  EEGLYQATYMPRAEGKCKVDVKYGGKPVPNSPFHMQV---LPGVDPSKVKVSGPGVRRSV 533

Query: 2521 -TGVSSEFIVNTQNAGSGALSVTIDGP--SKVQLDCRECPEG-HVVTYTPMAPGNYLIAI 2576
               + ++F V+T++AG   L   +  P  S ++   +   +G + V YTP   G Y I +
Sbjct: 534  PASLPAQFTVDTRDAGVADLECMVQRPDGSFIKPYFQNNEDGTYDVIYTPEDLGVYDIIV 713

Query: 2577 KYGGPQHIVGSPFKAKVTGPRLSGGHSLHETSTVLVETVTKXXXXXXXXXXXIPKFSSDA 2636
            KY G Q +  SPF  + T         L + S                      + +  A
Sbjct: 714  KYDG-QDVPRSPFNVEAT--------PLGDASQC--------------------RITDGA 806

Query: 2637 SKVVTRGPGLSQAFVGQKNSFTVDCSKAGTNMMMVGVHGPKTPCEEVYVKHMGNRVYNVT 2696
             +V+          + ++   TVD + AG   +   +  P     ++ +   G+  + ++
Sbjct: 807  ERVIP---------IEKETVITVDAADAGKGSVTCRIRSPSGSDIDIDIVDQGDGTFTIS 959

Query: 2697 YTVKEKGDYILIVKWGDESVP 2717
            +  +  G+YI+ +K+G   VP
Sbjct: 960  FIPQYAGEYIIEIKFGGNFVP 1022

 Score = 75.5 bits (184), Expect = 3e-13,   Method: Compositional matrix adjust.
 Identities = 75/264 (28%), Positives = 109/264 (41%), Gaps = 7/264 (2%)
 Frame = +3

Query: 2467 IRFIPHENGVHSIDVKFNGAHIPGSPFKIRVGEQSQAGDPGLVSAYGPGLEGGTTGVS-- 2524
            + + P + G + I V F    I  SPF +++       D   V  YGPGL+      +  
Sbjct: 87   VEYYPTKPGKYDISVLFGDKPIKDSPFSVKI---QNPVDASKVKCYGPGLDASEVAANLP 257

Query: 2525 SEFIVNTQNAGSGALSVTIDGP-SKVQLDCRECP--EG-HVVTYTPMAPGNYLIAIKYGG 2580
            + F V+ ++AG   L VT   P S  Q +    P  EG +  TY P A G   + +KYGG
Sbjct: 258  AVFTVDARDAGEAPLDVTFTDPLSGAQQEAEIVPVEEGLYQATYMPRAEGKCKVDVKYGG 437

Query: 2581 PQHIVGSPFKAKVTGPRLSGGHSLHETSTVLVETVTKXXXXXXXXXXXIPKFSSDASKVV 2640
             + +  SPF  +V    L G                                  D SKV 
Sbjct: 438  -KPVPNSPFHMQV----LPG---------------------------------VDPSKVK 503

Query: 2641 TRGPGLSQAF-VGQKNSFTVDCSKAGTNMMMVGVHGPKTPCEEVYVKHMGNRVYNVTYTV 2699
              GPG+ ++        FTVD   AG   +   V  P     + Y ++  +  Y+V YT 
Sbjct: 504  VSGPGVRRSVPASLPAQFTVDTRDAGVADLECMVQRPDGSFIKPYFQNNEDGTYDVIYTP 683

Query: 2700 KEKGDYILIVKWGDESVPGSPFKV 2723
            ++ G Y +IVK+  + VP SPF V
Sbjct: 684  EDLGVYDIIVKYDGQDVPRSPFNV 755

 Score = 72.8 bits (177), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 78/262 (29%), Positives = 115/262 (43%), Gaps = 18/262 (6%)
 Frame = +3

Query: 299  FTVQTVDAGVGEVLVYIEDPEGHTEEAKVVPNNDKDRTYAVSYVPKVAGLHKVTVLFAG- 357
             TV   DAG G V   I  P G   +  +V  +  D T+ +S++P+ AG + + + F G 
Sbjct: 840  ITVDAADAGKGSVTCRIRSPSGSDIDIDIV--DQGDGTFTISFIPQYAGEYIIEIKFGGN 1013

Query: 358  ---------QNIERSPFEVNVGMALGD----ANKV----SARGPGLEPVGNVANKPTYFD 400
                     + +    +E  +   + D    A++V    +A G GL        +P  F 
Sbjct: 1014 FVPDGQYTAEAVPEDEYEKYLQSRVVDDLIVADQVDQVNAAPGSGL-------YQPVDFQ 1172

Query: 401  IYTAGAGTGDVAVVIVDPQGRRDTVEVALEDKGDNTFRCTYRPVMEGPHTVHVAFAGAPI 460
             +  G     V+  ++ P G+  T    +ED  D T    Y+P   G H +HV +    I
Sbjct: 1173 -FPVGPIFNFVSASVIMPSGK--TSYPKIEDNRDGTVTVRYQPTETGLHELHVKYNNECI 1343

Query: 461  TRSPFPVHVAEACNPNACRASGRGLQPKGVRVKEVADFKVFTKGAGSGELKVTVKGPKGT 520
              SPF  HV ++ N     A G GL   GV V E A F + TK AG+G L + V+GP  T
Sbjct: 1344 QGSPFFFHV-DSVNSGYVTAYGPGLS-HGV-VYEPAVFTINTKEAGAGGLALAVEGPSKT 1514

Query: 521  EEPVKVREAGDGVFECEYYPVV 542
            E  +K  +  DG     Y P V
Sbjct: 1515 E--IKCVDNQDGTCNVSYLPSV 1574

 Score = 58.2 bits (139), Expect = 5e-08,   Method: Compositional matrix adjust.
 Identities = 54/195 (27%), Positives = 79/195 (40%), Gaps = 4/195 (2%)
 Frame = +3

Query: 2535 GSGALSVTIDGPSKVQLDCRECPEGHV-VTYTPMAPGNYLIAIKYGGPQHIVGSPFKAKV 2593
            G G L + I+GP + ++ C +  +G   V Y P  PG Y I++ +G  + I  SPF  K+
Sbjct: 3    GKGGLGLGIEGPVEAKMKCDDNRDGTCRVEYYPTKPGKYDISVLFGD-KPIKDSPFSVKI 179

Query: 2594 TGPRLSGGHSLHETSTVLVETVTKXXXXXXXXXXXIPKFSSDASKVVTRGPGLSQAFVGQ 2653
              P                                      DASKV   GPGL  + V  
Sbjct: 180  QNP-------------------------------------VDASKVKCYGPGLDASEVAA 248

Query: 2654 K--NSFTVDCSKAGTNMMMVGVHGPKTPCE-EVYVKHMGNRVYNVTYTVKEKGDYILIVK 2710
                 FTVD   AG   + V    P +  + E  +  +   +Y  TY  + +G   + VK
Sbjct: 249  NLPAVFTVDARDAGEAPLDVTFTDPLSGAQQEAEIVPVEEGLYQATYMPRAEGKCKVDVK 428

Query: 2711 WGDESVPGSPFKVNV 2725
            +G + VP SPF + V
Sbjct: 429  YGGKPVPNSPFHMQV 473

 Score = 38.5 bits (88), Expect = 0.038,   Method: Compositional matrix adjust.
 Identities = 28/72 (38%), Positives = 38/72 (52%)
 Frame = +3

Query: 274  LNPKKAIAYGPGIEPQGNTVLQPAHFTVQTVDAGVGEVLVYIEDPEGHTEEAKVVPNNDK 333
            +N     AYGPG+      V +PA FT+ T +AG G + + +E P     E K V N  +
Sbjct: 1377 VNSGYVTAYGPGL--SHGVVYEPAVFTINTKEAGAGGLALAVEGP--SKTEIKCVDN--Q 1538

Query: 334  DRTYAVSYVPKV 345
            D T  VSY+P V
Sbjct: 1539 DGTCNVSYLPSV 1574

 Score = 30.8 bits (68), Expect = 7.9,   Method: Compositional matrix adjust.
 Identities = 15/44 (34%), Positives = 23/44 (52%)
 Frame = +3

Query: 2633 SSDASKVVTRGPGLSQAFVGQKNSFTVDCSKAGTNMMMVGVHGP 2676
            S ++  V   GPGLS   V +   FT++  +AG   + + V GP
Sbjct: 1374 SVNSGYVTAYGPGLSHGVVYEPAVFTINTKEAGAGGLALAVEGP 1505
>16231
          Length = 1393

 Score =  251 bits (641), Expect(2) = 6e-83,   Method: Compositional matrix adjust.
 Identities = 140/288 (48%), Positives = 190/288 (65%), Gaps = 5/288 (1%)
 Frame = +3

Query: 309 GEVLVYIEDPEGHTEEAKVVPNNDKDRTYAVSYVPKVAGLHKVTVLFAGQNIERSPFEVN 368
           G+V V I +P+G  E  +V  NND++ TY+ +YVP + G +KV +LFA + I +SPF V 
Sbjct: 180 GDVEVSILNPKGVEETCEVEFNNDRNLTYSCAYVPTMEGHYKVNILFANKVIAKSPFTVT 359

Query: 369 VGMALGDANKVSARGPGLEPVGNVANKPTYFDIYTAGAGTGDVAVVIVDPQGRRDTVEVA 428
           V  A GDA+KV+A GPGLE  G VA K T+F+++  GAG G V VVI+DP GR+D V   
Sbjct: 360 VEGAAGDASKVTASGPGLEKTGVVATKKTFFEVFVKGAGNGKVDVVILDPHGRKDNVRPK 539

Query: 429 LE---DKGDNTFRCTYRPVMEGPHTVHVAFAGAPITRSPFPVHVAEACNPNACRASGRGL 485
           ++   DK D T+   Y  + +G H+V+V FAG+ I  SPF V VA A N  AC A+GRG+
Sbjct: 540 VQSAPDK-DATYLVEYVTIDQGLHSVNVFFAGSQIPNSPFGVQVAPASNAKACYATGRGV 716

Query: 486 QPKGVRVKEVADFKVFTKGAGSGELKVTVKGPKGTEEPVKVREAGDG--VFECEYYPVVP 543
           QP+GVRVK+ ADF V TKGAG GE+ V + GP G EE  ++++  D   V+EC Y P  P
Sbjct: 717 QPRGVRVKDRADFYVHTKGAGDGEVAVQIIGPGGVEEKCQLKKVPDQPEVWECVYNPSKP 896

Query: 544 GKYVVTITWGGYAIPRSPFEVQVSPEAGAQKVRAWGPGLETGQVGKSA 591
           G Y++ IT+G   I +SPF+++V P     K+RA+GPGLE G V + A
Sbjct: 897 GNYIINITFGDQHISKSPFKIEVGPYK-ESKIRAYGPGLEGGVVQQKA 1037

 Score = 77.8 bits (190), Expect(2) = 6e-83,   Method: Composition-based stats.
 Identities = 39/60 (65%), Positives = 46/60 (76%)
 Frame = +1

Query: 250 SVMTYLSQFPKAKLKPGAPVRSKQLNPKKAIAYGPGIEPQGNTVLQPAHFTVQTVDAGVG 309
           S+MTYLSQFP AKLK GAP+R + LNP +  AYGPG+EP+GN V  PA FTV+T  AG G
Sbjct: 7   SMMTYLSQFPNAKLKAGAPLRPR-LNPARVRAYGPGLEPKGNQVGAPARFTVETFSAGRG 183

 Score =  141 bits (356), Expect(3) = 1e-47,   Method: Compositional matrix adjust.
 Identities = 98/282 (34%), Positives = 146/282 (51%), Gaps = 11/282 (3%)
 Frame = +3

Query: 409 GDVAVVIVDPQGRRDTVEVALEDKGDNTFRCTYRPVMEGPHTVHVAFAGAPITRSPFPVH 468
           GDV V I++P+G  +T EV   +  + T+ C Y P MEG + V++ FA   I +SPF V 
Sbjct: 180 GDVEVSILNPKGVEETCEVEFNNDRNLTYSCAYVPTMEGHYKVNILFANKVIAKSPFTVT 359

Query: 469 VAEAC-NPNACRASGRGLQPKGVRVKEVADFKVFTKGAGSGELKVTVKGPKGTEEPV--K 525
           V  A  + +   ASG GL+  GV   +   F+VF KGAG+G++ V +  P G ++ V  K
Sbjct: 360 VEGAAGDASKVTASGPGLEKTGVVATKKTFFEVFVKGAGNGKVDVVILDPHGRKDNVRPK 539

Query: 526 VREA--GDGVFECEYYPVVPGKYVVTITWGGYAIPRSPFEVQVSPEAGAQKVRAWGPGLE 583
           V+ A   D  +  EY  +  G + V + + G  IP SPF VQV+P + A+   A G G++
Sbjct: 540 VQSAPDKDATYLVEYVTIDQGLHSVNVFFAGSQIPNSPFGVQVAPASNAKACYATGRGVQ 719

Query: 584 TG--QVGKSADFVVEAIGTEVGTLGFSIEGPSQAKIECDDKG----DGSCDVRYWPTEPG 637
               +V   ADF V   G   G +   I GP   + +C  K         +  Y P++PG
Sbjct: 720 PRGVRVKDRADFYVHTKGAGDGEVAVQIIGPGGVEEKCQLKKVPDQPEVWECVYNPSKPG 899

Query: 638 EYAVHVICDDEDIRDSPFIAHIQPAPPDCFPDKVKAFGPGLE 679
            Y +++   D+ I  SPF   + P        K++A+GPGLE
Sbjct: 900 NYIINITFGDQHISKSPFKIEVGPYK----ESKIRAYGPGLE 1013

 Score = 56.6 bits (135), Expect(3) = 1e-47,   Method: Compositional matrix adjust.
 Identities = 30/88 (34%), Positives = 50/88 (56%), Gaps = 2/88 (2%)
 Frame = +2

Query: 717  IKVIPNGDGTFRCSYVPTKPIKHTIIVSWGGVNVPKSPFRVNVGEGS--HPERVKVYGPG 774
            I+ + NGDG+    Y+PT P ++ + +     ++PKSPF  ++   +    E+V   GPG
Sbjct: 1109 IECLDNGDGSADVWYLPTMPGEYAVHILCSDEDIPKSPFMADIKPAADFDAEKVIAKGPG 1288

Query: 775  VEKTGLKANEPTYFTVDCSEAGQGDVSI 802
            +EK+G+  N+   FTVD   AG+  + I
Sbjct: 1289 LEKSGVAPNKWAEFTVDTKAAGKAPLVI 1372

 Score = 33.5 bits (75), Expect(3) = 1e-47,   Method: Composition-based stats.
 Identities = 16/32 (50%), Positives = 18/32 (56%)
 Frame = +1

Query: 378 KVSARGPGLEPVGNVANKPTYFDIYTAGAGTG 409
           +V A GPGLEP GN    P  F + T  AG G
Sbjct: 88  RVRAYGPGLEPKGNQVGAPARFTVETFSAGRG 183

 Score = 95.1 bits (235), Expect(3) = 4e-39,   Method: Compositional matrix adjust.
 Identities = 80/263 (30%), Positives = 113/263 (42%), Gaps = 13/263 (4%)
 Frame = +3

Query: 1186 EAELTIEILSDAGVK--AEVLIQNNADGTYHITYSPAFPGTYTITIKYGGHPIPKFPTRV 1243
            + ++ + IL+  GV+   EV   N+ + TY   Y P   G Y + I +    I K P  V
Sbjct: 177  KGDVEVSILNPKGVEETCEVEFNNDRNLTYSCAYVPTMEGHYKVNILFANKVIAKSPFTV 356

Query: 1244 HVQPAV-DTSGIKVSGPGVEPHGVLREVTTEFTVDARSLTATGGNHVTARVLNPSGAKTD 1302
             V+ A  D S +  SGPG+E  GV+    T F V  +     G   V   +L+P G K +
Sbjct: 357  TVEGAAGDASKVTASGPGLEKTGVVATKKTFFEVFVK---GAGNGKVDVVILDPHGRKDN 527

Query: 1303 T----YVTDNGDGTYRVQYTAYEEGVHLVEVLYDEVAVPKSPFRVGVTEGCDPTRVRAFG 1358
                     + D TY V+Y   ++G+H V V +    +P SPF V V    +     A G
Sbjct: 528  VRPKVQSAPDKDATYLVEYVTIDQGLHSVNVFFAGSQIPNSPFGVQVAPASNAKACYATG 707

Query: 1359 PGLE--GGLVNKANRFTVXXXXXXXXXXXXXXXXPSEAKMSCKDNK--DGSCTVE--YIP 1412
             G++  G  V     F V                P   +  C+  K  D     E  Y P
Sbjct: 708  RGVQPRGVRVKDRADFYVHTKGAGDGEVAVQIIGPGGVEEKCQLKKVPDQPEVWECVYNP 887

Query: 1413 FTPGDYDVNITFGGQPIPGSPFR 1435
              PG+Y +NITFG Q I  SPF+
Sbjct: 888  SKPGNYIINITFGDQHISKSPFK 956

 Score = 73.9 bits (180), Expect(3) = 4e-39,   Method: Compositional matrix adjust.
 Identities = 44/118 (37%), Positives = 66/118 (55%), Gaps = 2/118 (1%)
 Frame = +2

Query: 1466 FTVDCSQAGRAPLQVAVLGPTGVAEPVEVRDNGDGTHTVHYTPATDGPYTVAVKYADQEV 1525
            FTV+ +    A L  ++ GP+     +E  DNGDG+  V Y P   G Y V +  +D+++
Sbjct: 1040 FTVETNGETGA-LGFSIEGPSQAQ--IECLDNGDGSADVWYLPTMPGEYAVHILCSDEDI 1210

Query: 1526 PRSPFKIKVLPS--HDASKVRASGPGLNASGIPASLPVEFTIDARDAGQGLLTVQILD 1581
            P+SPF   + P+   DA KV A GPGL  SG+  +   EFT+D + AG+  L +  +D
Sbjct: 1211 PKSPFMADIKPAADFDAEKVIAKGPGLEKSGVAPNKWAEFTVDTKAAGKAPLVITGMD 1384

 Score = 34.3 bits (77), Expect(3) = 4e-39,   Method: Composition-based stats.
 Identities = 20/53 (37%), Positives = 29/53 (54%), Gaps = 4/53 (7%)
 Frame = +1

Query: 1139 AHIPGSPFKA--TIQPVFDPSKVRASGPGLER--GKAGEAATFTVDCSEAGEA 1187
            +  P +  KA   ++P  +P++VRA GPGLE    + G  A FTV+   AG  
Sbjct: 25   SQFPNAKLKAGAPLRPRLNPARVRAYGPGLEPKGNQVGAPARFTVETFSAGRG 183

 Score =  112 bits (279), Expect(3) = 6e-38,   Method: Compositional matrix adjust.
 Identities = 87/290 (30%), Positives = 133/290 (45%), Gaps = 3/290 (1%)
 Frame = +3

Query: 700 KGDLKLYAQDADGCPIDIKVIPNGDG--TFRCSYVPTKPIKHTIIVSWGGVNVPKSPFRV 757
           KGD+++   +  G     +V  N D   T+ C+YVPT    + + + +    + KSPF V
Sbjct: 177 KGDVEVSILNPKGVEETCEVEFNNDRNLTYSCAYVPTMEGHYKVNILFANKVIAKSPFTV 356

Query: 758 NV-GEGSHPERVKVYGPGVEKTGLKANEPTYFTVDCSEAGQGDVSIGIKCAPGVVGPVEA 816
            V G      +V   GPG+EKTG+ A + T+F V    AG G V + I    G    V  
Sbjct: 357 TVEGAAGDASKVTASGPGLEKTGVVATKKTFFEVFVKGAGNGKVDVVILDPHGRKDNVRP 536

Query: 817 XXXXXXXXXXXXTFTVKYTPPGAGHYTIMVLFANQEIPASPFHIKVDPSHDASKVKAEGP 876
                       T+ V+Y     G +++ V FA  +IP SPF ++V P+ +A    A G 
Sbjct: 537 KVQSAPDKDA--TYLVEYVTIDQGLHSVNVFFAGSQIPNSPFGVQVAPASNAKACYATGR 710

Query: 877 GLSRTGVEVGKPTHFTVLTKGAGKAKLDVHFAGAAKGEAVRDFEIIDNHDYSYTVKYTAV 936
           G+   GV V     F V TKGAG  ++ V   G    E     + + +    +   Y   
Sbjct: 711 GVQPRGVRVKDRADFYVHTKGAGDGEVAVQIIGPGGVEEKCQLKKVPDQPEVWECVYNPS 890

Query: 937 QQGNMAVTVTYGGDPVPKSPFVVNVAPPLDLSKVKVQGLNSKVAVGQEQA 986
           + GN  + +T+G   + KSPF + V  P   SK++  G   +  V Q++A
Sbjct: 891 KPGNYIINITFGDQHISKSPFKIEVG-PYKESKIRAYGPGLEGGVVQQKA 1037

 Score = 44.3 bits (103), Expect(3) = 6e-38,   Method: Composition-based stats.
 Identities = 20/41 (48%), Positives = 27/41 (65%)
 Frame = +1

Query: 661 PAPPDCFPDKVKAFGPGLEPTGCIVDRPAEFTIDARAAGKG 701
           P  P   P +V+A+GPGLEP G  V  PA FT++  +AG+G
Sbjct: 61  PLRPRLNPARVRAYGPGLEPKGNQVGAPARFTVETFSAGRG 183

 Score = 42.7 bits (99), Expect(3) = 6e-38,   Method: Compositional matrix adjust.
 Identities = 41/111 (36%), Positives = 53/111 (47%), Gaps = 5/111 (4%)
 Frame = +2

Query: 984  EQAFSVNTRGAGGQGQLDVRMTSPSRRPIPCKLEPGGGAEAQAVRYMPPEEGPYKVDITY 1043
            E  F+V T G    G L   +  PS+  I C L+ G G+    V Y+P   G Y V I  
Sbjct: 1031 EGRFTVETNGE--TGALGFSIEGPSQAQIEC-LDNGDGS--ADVWYLPTMPGEYAVHILC 1195

Query: 1044 DGHPVPGSPFAVEGVLPP---DPSKVCAYGPGL-KGGLV-GTPAPFSIDTK 1089
                +P SPF  + + P    D  KV A GPGL K G+     A F++DTK
Sbjct: 1196 SDEDIPKSPFMAD-IKPAADFDAEKVIAKGPGLEKSGVAPNKWAEFTVDTK 1345

 Score =  110 bits (274), Expect(2) = 5e-34,   Method: Compositional matrix adjust.
 Identities = 79/224 (35%), Positives = 106/224 (47%), Gaps = 2/224 (0%)
 Frame = +3

Query: 278 KAIAYGPGIEPQGNTVLQPAHFTVQTVDAGVGEVLVYIEDPEGHTEEA--KVVPNNDKDR 335
           K  A GPG+E  G    +   F V    AG G+V V I DP G  +    KV    DKD 
Sbjct: 387 KVTASGPGLEKTGVVATKKTFFEVFVKGAGNGKVDVVILDPHGRKDNVRPKVQSAPDKDA 566

Query: 336 TYAVSYVPKVAGLHKVTVLFAGQNIERSPFEVNVGMALGDANKVSARGPGLEPVGNVANK 395
           TY V YV    GLH V V FAG  I  SPF V V  A  +A    A G G++P G     
Sbjct: 567 TYLVEYVTIDQGLHSVNVFFAGSQIPNSPFGVQVAPA-SNAKACYATGRGVQPRGVRVKD 743

Query: 396 PTYFDIYTAGAGTGDVAVVIVDPQGRRDTVEVALEDKGDNTFRCTYRPVMEGPHTVHVAF 455
              F ++T GAG G+VAV I+ P G  +  ++         + C Y P   G + +++ F
Sbjct: 744 RADFYVHTKGAGDGEVAVQIIGPGGVEEKCQLKKVPDQPEVWECVYNPSKPGNYIINITF 923

Query: 456 AGAPITRSPFPVHVAEACNPNACRASGRGLQPKGVRVKEVADFK 499
               I++SPF + V      +  RA G GL+   V+ K V  ++
Sbjct: 924 GDQHISKSPFKIEVGPY-KESKIRAYGPGLEGGVVQQKAVLLWR 1052

 Score = 55.5 bits (132), Expect(2) = 5e-34,   Method: Compositional matrix adjust.
 Identities = 39/103 (37%), Positives = 56/103 (54%), Gaps = 4/103 (3%)
 Frame = +2

Query: 498  FKVFTKGAGSGELKVTVKGPKGTEEPVKVREAGDGVFECEYYPVVPGKYVVTITWGGYAI 557
            F V T G  +G L  +++GP  ++  ++  + GDG  +  Y P +PG+Y V I      I
Sbjct: 1040 FTVETNGE-TGALGFSIEGP--SQAQIECLDNGDGSADVWYLPTMPGEYAVHILCSDEDI 1210

Query: 558  PRSPFEVQVSPEA--GAQKVRAWGPGLETGQVG--KSADFVVE 596
            P+SPF   + P A   A+KV A GPGLE   V   K A+F V+
Sbjct: 1211 PKSPFMADIKPAADFDAEKVIAKGPGLEKSGVAPNKWAEFTVD 1339

 Score =  111 bits (277), Expect(3) = 2e-33,   Method: Compositional matrix adjust.
 Identities = 89/277 (32%), Positives = 122/277 (44%), Gaps = 15/277 (5%)
 Frame = +3

Query: 1289 VTARVLNPSGAKTDTYVTDNGDG--TYRVQYTAYEEGVHLVEVLYDEVAVPKSPFRVGVT 1346
            V   +LNP G +    V  N D   TY   Y    EG + V +L+    + KSPF V V 
Sbjct: 186  VEVSILNPKGVEETCEVEFNNDRNLTYSCAYVPTMEGHYKVNILFANKVIAKSPFTVTV- 362

Query: 1347 EGC--DPTRVRAFGPGLE--GGLVNKANRFTVXXXXXXXXXXXXXXXXPS------EAKM 1396
            EG   D ++V A GPGLE  G +  K   F V                P         K+
Sbjct: 363  EGAAGDASKVTASGPGLEKTGVVATKKTFFEVFVKGAGNGKVDVVILDPHGRKDNVRPKV 542

Query: 1397 SCKDNKDGSCTVEYIPFTPGDYDVNITFGGQPIPGSPFRXXXXXXXXXXXXXCSGPGLG- 1455
                +KD +  VEY+    G + VN+ F G  IP SPF               +G G+  
Sbjct: 543  QSAPDKDATYLVEYVTIDQGLHSVNVFFAGSQIPNSPFGVQVAPASNAKACYATGRGVQP 722

Query: 1456 TGVRARVPQTFTVDCSQAGRAPLQVAVLGPTGVAEPVEVRDNGDGTHTVH--YTPATDGP 1513
             GVR +    F V    AG   + V ++GP GV E  +++   D        Y P+  G 
Sbjct: 723  RGVRVKDRADFYVHTKGAGDGEVAVQIIGPGGVEEKCQLKKVPDQPEVWECVYNPSKPGN 902

Query: 1514 YTVAVKYADQEVPRSPFKIKVLPSHDASKVRASGPGL 1550
            Y + + + DQ + +SPFKI+V P +  SK+RA GPGL
Sbjct: 903  YIINITFGDQHISKSPFKIEVGP-YKESKIRAYGPGL 1010

 Score = 46.6 bits (109), Expect(3) = 2e-33,   Method: Compositional matrix adjust.
 Identities = 36/99 (36%), Positives = 44/99 (44%), Gaps = 2/99 (2%)
 Frame = +2

Query: 1586 PKKANIR--DNGDGTYTVSYLPDMSGRYTITIKYGGDEIPYSPFRIHALPTGDASKCLVT 1643
            P +A I   DNGDG+  V YLP M G Y + I    ++IP SPF     P  D     V 
Sbjct: 1094 PSQAQIECLDNGDGSADVWYLPTMPGEYAVHILCSDEDIPKSPFMADIKPAADFDAEKVI 1273

Query: 1644 VSIGGHGLGACLGPRIQIGEETVITVDAKAAGKGKVTCT 1682
                G GL       +   +    TVD KAAGK  +  T
Sbjct: 1274 AK--GPGLEKS---GVAPNKWAEFTVDTKAAGKAPLVIT 1375

 Score = 26.2 bits (56), Expect(3) = 2e-33,   Method: Composition-based stats.
 Identities = 13/46 (28%), Positives = 22/46 (47%)
 Frame = +1

Query: 1235 PIPKFPTRVHVQPAVDTSGIKVSGPGVEPHGVLREVTTEFTVDARS 1280
            P  K      ++P ++ + ++  GPG+EP G        FTV+  S
Sbjct: 34   PNAKLKAGAPLRPRLNPARVRAYGPGLEPKGNQVGAPARFTVETFS 171

 Score =  140 bits (353), Expect = 7e-33,   Method: Compositional matrix adjust.
 Identities = 89/271 (32%), Positives = 138/271 (50%), Gaps = 12/271 (4%)
 Frame = +3

Query: 1475 RAPLQVAVLGPTGVAEPVEVRDNGDG--THTVHYTPATDGPYTVAVKYADQEVPRSPFKI 1532
            +  ++V++L P GV E  EV  N D   T++  Y P  +G Y V + +A++ + +SPF +
Sbjct: 177  KGDVEVSILNPKGVEETCEVEFNNDRNLTYSCAYVPTMEGHYKVNILFANKVIAKSPFTV 356

Query: 1533 KVL-PSHDASKVRASGPGLNASGIPASLPVEFTIDARDAGQGLLTVQILDPEGKPKKANI 1591
             V   + DASKV ASGPGL  +G+ A+    F +  + AG G + V ILDP G  +K N+
Sbjct: 357  TVEGAAGDASKVTASGPGLEKTGVVATKKTFFEVFVKGAGNGKVDVVILDPHG--RKDNV 530

Query: 1592 R------DNGDGTYTVSYLPDMSGRYTITIKYGGDEIPYSPFRIHALPTGDASKCLVTVS 1645
            R       + D TY V Y+    G +++ + + G +IP SPF +   P  +A  C  T  
Sbjct: 531  RPKVQSAPDKDATYLVEYVTIDQGLHSVNVFFAGSQIPNSPFGVQVAPASNAKACYAT-- 704

Query: 1646 IGGHGLGACLGPR-IQIGEETVITVDAKAAGKGKVTCTVSTPDGAE--LDVDVVENHDGT 1702
                  G  + PR +++ +     V  K AG G+V   +  P G E    +  V +    
Sbjct: 705  ------GRGVQPRGVRVKDRADFYVHTKGAGDGEVAVQIIGPGGVEEKCQLKKVPDQPEV 866

Query: 1703 FDIYYTAPEPGKYVITIRFGGEHIPNSPFHV 1733
            ++  Y   +PG Y+I I FG +HI  SPF +
Sbjct: 867  WECVYNPSKPGNYIINITFGDQHISKSPFKI 959

 Score = 93.2 bits (230), Expect(2) = 3e-31,   Method: Compositional matrix adjust.
 Identities = 76/293 (25%), Positives = 132/293 (45%), Gaps = 24/293 (8%)
 Frame = +3

Query: 1796 KGELTGEVRMPSG--KTARPNITDNKDGTITVRYAPTEKGLHQMGIKYDGNHIPGSPLQF 1853
            KG++   +  P G  +T      ++++ T +  Y PT +G +++ I +    I  SP   
Sbjct: 177  KGDVEVSILNPKGVEETCEVEFNNDRNLTYSCAYVPTMEGHYKVNILFANKVIAKSPFTV 356

Query: 1854 YVD--AINSRHVSAYGPGLSH-GMV-NKPATFTIVTKDAGEGGLSLAVEGPS------KA 1903
             V+  A ++  V+A GPGL   G+V  K   F +  K AG G + + +  P       + 
Sbjct: 357  TVEGAAGDASKVTASGPGLEKTGVVATKKTFFEVFVKGAGNGKVDVVILDPHGRKDNVRP 536

Query: 1904 EITCKDNKDGTCTVSYLPTAPGDYSIIVRFDDKHIPGSPFTAKITGDDSMRTSQ------ 1957
            ++    +KD T  V Y+    G +S+ V F    IP SPF  ++    + +         
Sbjct: 537  KVQSAPDKDATYLVEYVTIDQGLHSVNVFFAGSQIPNSPFGVQVAPASNAKACYATGRGV 716

Query: 1958 ----LNVGTSTDVSLKITEGDLSQLTASIRAPSGNEEPCLLKRLPNR--HIGISFTPKEV 2011
                + V    D  +        ++   I  P G EE C LK++P++       + P + 
Sbjct: 717  QPRGVRVKDRADFYVHTKGAGDGEVAVQIIGPGGVEEKCQLKKVPDQPEVWECVYNPSKP 896

Query: 2012 GEHVVSVRKSGKHVTNSPFKILVGPSEIGDASKVRVWGKGLSEGQTFQVAEFI 2064
            G +++++    +H++ SPFKI VGP +    SK+R +G GL  G   Q A  +
Sbjct: 897  GNYIINITFGDQHISKSPFKIEVGPYK---ESKIRAYGPGLEGGVVQQKAVLL 1046

 Score = 62.8 bits (151), Expect(2) = 3e-31,   Method: Compositional matrix adjust.
 Identities = 31/67 (46%), Positives = 40/67 (59%)
 Frame = +2

Query: 2063 FIVDTRNAGYGGLGLSIEGPSKVDINCEDMEDGTCKVTYCPTEPGTYIINIKFADKHVPG 2122
            F V+T N   G LG SIEGPS+  I C D  DG+  V Y PT PG Y ++I  +D+ +P 
Sbjct: 1040 FTVET-NGETGALGFSIEGPSQAQIECLDNGDGSADVWYLPTMPGEYAVHILCSDEDIPK 1216

Query: 2123 SPFTVKV 2129
            SPF   +
Sbjct: 1217 SPFMADI 1237

 Score =  121 bits (303), Expect(2) = 7e-31,   Method: Compositional matrix adjust.
 Identities = 90/280 (32%), Positives = 135/280 (48%), Gaps = 11/280 (3%)
 Frame = +3

Query: 1100 VEGPCEAKIECQDNGDGSCAVSYLPTEPGEYTINILFAEAHIPGSPFKATIQ-PVFDPSK 1158
            VE  CE +     N   SCA  Y+PT  G Y +NILFA   I  SPF  T++    D SK
Sbjct: 216  VEETCEVEFNNDRNLTYSCA--YVPTMEGHYKVNILFANKVIAKSPFTVTVEGAAGDASK 389

Query: 1159 VRASGPGLERGKAGEAAT----FTVDCSEAGEAELTIEILSDAG----VKAEVLIQNNAD 1210
            V ASGPGLE  K G  AT    F V    AG  ++ + IL   G    V+ +V    + D
Sbjct: 390  VTASGPGLE--KTGVVATKKTFFEVFVKGAGNGKVDVVILDPHGRKDNVRPKVQSAPDKD 563

Query: 1211 GTYHITYSPAFPGTYTITIKYGGHPIPKFPTRVHVQPAVDTSGIKVSGPGVEPHGVLREV 1270
             TY + Y     G +++ + + G  IP  P  V V PA +      +G GV+P GV  + 
Sbjct: 564  ATYLVEYVTIDQGLHSVNVFFAGSQIPNSPFGVQVAPASNAKACYATGRGVQPRGVRVKD 743

Query: 1271 TTEFTVDARSLTATGGNHVTARVLNPSGAKTDTYVTDNGDG--TYRVQYTAYEEGVHLVE 1328
              +F V  +     G   V  +++ P G +    +    D    +   Y   + G +++ 
Sbjct: 744  RADFYVHTK---GAGDGEVAVQIIGPGGVEEKCQLKKVPDQPEVWECVYNPSKPGNYIIN 914

Query: 1329 VLYDEVAVPKSPFRVGVTEGCDPTRVRAFGPGLEGGLVNK 1368
            + + +  + KSPF++ V      +++RA+GPGLEGG+V +
Sbjct: 915  ITFGDQHISKSPFKIEVGP-YKESKIRAYGPGLEGGVVQQ 1031

 Score = 33.5 bits (75), Expect(2) = 7e-31,   Method: Composition-based stats.
 Identities = 16/29 (55%), Positives = 22/29 (75%), Gaps = 2/29 (6%)
 Frame = +1

Query: 1062 DPSKVCAYGPGL--KGGLVGTPAPFSIDT 1088
            +P++V AYGPGL  KG  VG PA F+++T
Sbjct: 79   NPARVRAYGPGLEPKGNQVGAPARFTVET 165

 Score =  133 bits (334), Expect = 1e-30,   Method: Compositional matrix adjust.
 Identities = 79/155 (50%), Positives = 97/155 (62%), Gaps = 2/155 (1%)
 Frame = +2

Query: 559  RSPFEVQVSPEAGAQKVRAWGPGLETGQVGKSAD--FVVEAIGTEVGTLGFSIEGPSQAK 616
            + P + +  P  G Q    W      G+ G +A+  F VE  G E G LGFSIEGPSQA+
Sbjct: 941  QKPLQDRGGPLXGEQDQGLW---TRPGRRGGAAEGRFTVETNG-ETGALGFSIEGPSQAQ 1108

Query: 617  IECDDKGDGSCDVRYWPTEPGEYAVHVICDDEDIRDSPFIAHIQPAPPDCFPDKVKAFGP 676
            IEC D GDGS DV Y PT PGEYAVH++C DEDI  SPF+A I+PA  D   +KV A GP
Sbjct: 1109 IECLDNGDGSADVWYLPTMPGEYAVHILCSDEDIPKSPFMADIKPA-ADFDAEKVIAKGP 1285

Query: 677  GLEPTGCIVDRPAEFTIDARAAGKGDLKLYAQDAD 711
            GLE +G   ++ AEFT+D +AAGK  L +   D D
Sbjct: 1286 GLEKSGVAPNKWAEFTVDTKAAGKAPLVITGMDTD 1390

 Score =  106 bits (265), Expect(2) = 1e-25,   Method: Compositional matrix adjust.
 Identities = 78/249 (31%), Positives = 110/249 (44%), Gaps = 8/249 (3%)
 Frame = +3

Query: 1393 EAKMSCKDNKDGSCTVEYIPFTPGDYDVNITFGGQPIPGSPFRXXXXXXX-XXXXXXCSG 1451
            E + +   N   SC   Y+P   G Y VNI F  + I  SPF                SG
Sbjct: 231  EVEFNNDRNLTYSCA--YVPTMEGHYKVNILFANKVIAKSPFTVTVEGAAGDASKVTASG 404

Query: 1452 PGL-GTGVRARVPQTFTVDCSQAGRAPLQVAVLGPTG----VAEPVEVRDNGDGTHTVHY 1506
            PGL  TGV A     F V    AG   + V +L P G    V   V+   + D T+ V Y
Sbjct: 405  PGLEKTGVVATKKTFFEVFVKGAGNGKVDVVILDPHGRKDNVRPKVQSAPDKDATYLVEY 584

Query: 1507 TPATDGPYTVAVKYADQEVPRSPFKIKVLPSHDASKVRASGPGLNASGIPASLPVEFTID 1566
                 G ++V V +A  ++P SPF ++V P+ +A    A+G G+   G+      +F + 
Sbjct: 585  VTIDQGLHSVNVFFAGSQIPNSPFGVQVAPASNAKACYATGRGVQPRGVRVKDRADFYVH 764

Query: 1567 ARDAGQGLLTVQILDPEGKPKKANIRDNGDG--TYTVSYLPDMSGRYTITIKYGGDEIPY 1624
             + AG G + VQI+ P G  +K  ++   D    +   Y P   G Y I I +G   I  
Sbjct: 765  TKGAGDGEVAVQIIGPGGVEEKCQLKKVPDQPEVWECVYNPSKPGNYIINITFGDQHISK 944

Query: 1625 SPFRIHALP 1633
            SPF+I   P
Sbjct: 945  SPFKIEVGP 971

 Score = 30.8 bits (68), Expect(2) = 1e-25,   Method: Composition-based stats.
 Identities = 16/27 (59%), Positives = 18/27 (66%), Gaps = 2/27 (7%)
 Frame = +1

Query: 1350 DPTRVRAFGPGLE--GGLVNKANRFTV 1374
            +P RVRA+GPGLE  G  V    RFTV
Sbjct: 79   NPARVRAYGPGLEPKGNQVGAPARFTV 159

 Score =  100 bits (248), Expect(2) = 2e-25,   Method: Compositional matrix adjust.
 Identities = 87/293 (29%), Positives = 134/293 (45%), Gaps = 15/293 (5%)
 Frame = +3

Query: 900  KAKLDVHFAGAAKGEAVRDFEIIDNHDYSYTVKYTAVQQGNMAVTVTYGGDPVPKSPFVV 959
            K  ++V        E   + E  ++ + +Y+  Y    +G+  V + +    + KSPF V
Sbjct: 177  KGDVEVSILNPKGVEETCEVEFNNDRNLTYSCAYVPTMEGHYKVNILFANKVIAKSPFTV 356

Query: 960  NVAPPL-DLSKVKVQG---LNSKVAVGQEQAFSVNTRGAGGQGQLDVRMTSPSRRPIPCK 1015
             V     D SKV   G     + V   ++  F V  +GAG  G++DV +  P  R    +
Sbjct: 357  TVEGAAGDASKVTASGPGLEKTGVVATKKTFFEVFVKGAG-NGKVDVVILDPHGRKDNVR 533

Query: 1016 LEPGGGAEAQA---VRYMPPEEGPYKVDITYDGHPVPGSPFAVEGVLPPDPSKVC-AYGP 1071
             +     +  A   V Y+  ++G + V++ + G  +P SPF V+ V P   +K C A G 
Sbjct: 534  PKVQSAPDKDATYLVEYVTIDQGLHSVNVFFAGSQIPNSPFGVQ-VAPASNAKACYATGR 710

Query: 1072 GL--KGGLVGTPAPFSIDTKXXXXXXXXXXVEGPCEAKIECQ-----DNGDGSCAVSYLP 1124
            G+  +G  V   A F + TK          + GP   + +CQ     D  +    V Y P
Sbjct: 711  GVQPRGVRVKDRADFYVHTKGAGDGEVAVQIIGPGGVEEKCQLKKVPDQPEVWECV-YNP 887

Query: 1125 TEPGEYTINILFAEAHIPGSPFKATIQPVFDPSKVRASGPGLERGKAGEAATF 1177
            ++PG Y INI F + HI  SPFK  + P +  SK+RA GPGLE G   + A  
Sbjct: 888  SKPGNYIINITFGDQHISKSPFKIEVGP-YKESKIRAYGPGLEGGVVQQKAVL 1043

 Score = 36.6 bits (83), Expect(2) = 2e-25,   Method: Composition-based stats.
 Identities = 22/60 (36%), Positives = 34/60 (56%), Gaps = 1/60 (1%)
 Frame = +1

Query: 843 TIMVLFANQEIPA-SPFHIKVDPSHDASKVKAEGPGLSRTGVEVGKPTHFTVLTKGAGKA 901
           T +  F N ++ A +P   +++P+    +V+A GPGL   G +VG P  FTV T  AG+ 
Sbjct: 16  TYLSQFPNAKLKAGAPLRPRLNPA----RVRAYGPGLEPKGNQVGAPARFTVETFSAGRG 183

 Score =  111 bits (277), Expect = 5e-24,   Method: Compositional matrix adjust.
 Identities = 87/268 (32%), Positives = 133/268 (49%), Gaps = 24/268 (8%)
 Frame = +3

Query: 2358 AEIAFEDRKDGSCGVSYVVQEPGDYEVSIKFNDEHIPDSPFVVPVASLSDDARRLTVTS- 2416
             E+ F + ++ +   +YV    G Y+V+I F ++ I  SPF V V   + DA ++T +  
Sbjct: 228  CEVEFNNDRNLTYSCAYVPTMEGHYKVNILFANKVIAKSPFTVTVEGAAGDASKVTASGP 407

Query: 2417 -LQETGLKVNQPASFAVQLNGA-RGVIDARVHTPSGA---VEECYVSELDSDK-HTIRFI 2470
             L++TG+   +   F V + GA  G +D  +  P G    V     S  D D  + + ++
Sbjct: 408  GLEKTGVVATKKTFFEVFVKGAGNGKVDVVILDPHGRKDNVRPKVQSAPDKDATYLVEYV 587

Query: 2471 PHENGVHSIDVKFNGAHIPGSPFKIRVGEQSQAGDPGLVSAYGPGLE--GGTTGVSSEFI 2528
              + G+HS++V F G+ IP SPF ++V   S A       A G G++  G      ++F 
Sbjct: 588  TIDQGLHSVNVFFAGSQIPNSPFGVQVAPASNA---KACYATGRGVQPRGVRVKDRADFY 758

Query: 2529 VNTQNAGSGALSVTIDGPSKVQLDCR-----ECPEGHVVTYTPMAPGNYLIAIKYGGPQH 2583
            V+T+ AG G ++V I GP  V+  C+     + PE     Y P  PGNY+I I +G  QH
Sbjct: 759  VHTKGAGDGEVAVQIIGPGGVEEKCQLKKVPDQPEVWECVYNPSKPGNYIINITFGD-QH 935

Query: 2584 IVGSPFKAKV----------TGPRLSGG 2601
            I  SPFK +V           GP L GG
Sbjct: 936  ISKSPFKIEVGPYKESKIRAYGPGLEGG 1019

 Score =  106 bits (264), Expect = 1e-22,   Method: Compositional matrix adjust.
 Identities = 87/284 (30%), Positives = 132/284 (46%), Gaps = 14/284 (4%)
 Frame = +3

Query: 2250 DMTAQVTSPSGKTEAAEIVEGEDS--AYSVRFVPQEMGPHTVTVKYRGQHVPGSPFQFTV 2307
            D+   + +P G  E  E+    D    YS  +VP   G + V + +  + +  SPF  TV
Sbjct: 183  DVEVSILNPKGVEETCEVEFNNDRNLTYSCAYVPTMEGHYKVNILFANKVIAKSPFTVTV 362

Query: 2308 GPLGEGGAHKVRAGGTGLERG--VAGVPAEFSIWTREAGAGGLSIAVEGPS------KAE 2359
                 G A KV A G GLE+   VA     F ++ + AG G + + +  P       + +
Sbjct: 363  -EGAAGDASKVTASGPGLEKTGVVATKKTFFEVFVKGAGNGKVDVVILDPHGRKDNVRPK 539

Query: 2360 IAFEDRKDGSCGVSYVVQEPGDYEVSIKFNDEHIPDSPFVVPVASLSD-DARRLTVTSLQ 2418
            +     KD +  V YV  + G + V++ F    IP+SPF V VA  S+  A   T   +Q
Sbjct: 540  VQSAPDKDATYLVEYVTIDQGLHSVNVFFAGSQIPNSPFGVQVAPASNAKACYATGRGVQ 719

Query: 2419 ETGLKVNQPASFAVQLNGA-RGVIDARVHTPSGAVEECYVSELDSDKHTIRFI--PHENG 2475
              G++V   A F V   GA  G +  ++  P G  E+C + ++         +  P + G
Sbjct: 720  PRGVRVKDRADFYVHTKGAGDGEVAVQIIGPGGVEEKCQLKKVPDQPEVWECVYNPSKPG 899

Query: 2476 VHSIDVKFNGAHIPGSPFKIRVGEQSQAGDPGLVSAYGPGLEGG 2519
             + I++ F   HI  SPFKI VG   ++     + AYGPGLEGG
Sbjct: 900  NYIINITFGDQHISKSPFKIEVGPYKESK----IRAYGPGLEGG 1019

 Score = 87.4 bits (215), Expect(2) = 7e-20,   Method: Compositional matrix adjust.
 Identities = 74/277 (26%), Positives = 129/277 (46%), Gaps = 25/277 (9%)
 Frame = +3

Query: 1890 EGGLSLAVEGPSKAEITCK----DNKDGTCTVSYLPTAPGDYSIIVRFDDKHIPGSPFTA 1945
            +G + +++  P   E TC+    ++++ T + +Y+PT  G Y + + F +K I  SPFT 
Sbjct: 177  KGDVEVSILNPKGVEETCEVEFNNDRNLTYSCAYVPTMEGHYKVNILFANKVIAKSPFTV 356

Query: 1946 KI---TGDDSMRTSQ--------LNVGTSTDVSLKITEGDLSQLTASIRAPSGNEEPCL- 1993
             +    GD S  T+         +     T   + +      ++   I  P G ++    
Sbjct: 357  TVEGAAGDASKVTASGPGLEKTGVVATKKTFFEVFVKGAGNGKVDVVILDPHGRKDNVRP 536

Query: 1994 -LKRLPNRHIG--ISFTPKEVGEHVVSVRKSGKHVTNSPFKILVGPSEIGDASKVRVWGK 2050
             ++  P++     + +   + G H V+V  +G  + NSPF + V P+   +A      G+
Sbjct: 537  KVQSAPDKDATYLVEYVTIDQGLHSVNVFFAGSQIPNSPFGVQVAPAS--NAKACYATGR 710

Query: 2051 GLSEG--QTFQVAEFIVDTRNAGYGGLGLSIEGPSKVDINCEDM----EDGTCKVTYCPT 2104
            G+     +    A+F V T+ AG G + + I GP  V+  C+      +    +  Y P+
Sbjct: 711  GVQPRGVRVKDRADFYVHTKGAGDGEVAVQIIGPGGVEEKCQLKKVPDQPEVWECVYNPS 890

Query: 2105 EPGTYIINIKFADKHVPGSPFTVKVTGEGRMKESITR 2141
            +PG YIINI F D+H+  SPF ++V   G  KES  R
Sbjct: 891  KPGNYIINITFGDQHISKSPFKIEV---GPYKESKIR 992

 Score = 30.4 bits (67), Expect(2) = 7e-20,   Method: Composition-based stats.
 Identities = 20/46 (43%), Positives = 24/46 (52%), Gaps = 2/46 (4%)
 Frame = +1

Query: 1848 GSPLQFYVDAINSRHVSAYGPGLS--HGMVNKPATFTIVTKDAGEG 1891
            G+PL+     +N   V AYGPGL      V  PA FT+ T  AG G
Sbjct: 55   GAPLR---PRLNPARVRAYGPGLEPKGNQVGAPARFTVETFSAGRG 183

 Score = 62.0 bits (149), Expect(2) = 9e-20,   Method: Compositional matrix adjust.
 Identities = 36/95 (37%), Positives = 53/95 (55%), Gaps = 3/95 (3%)
 Frame = +2

Query: 2346 GGLSIAVEGPSKAEIAFEDRKDGSCGVSYVVQEPGDYEVSIKFNDEHIPDSPFVVPVASL 2405
            G L  ++EGPS+A+I   D  DGS  V Y+   PG+Y V I  +DE IP SPF+  +   
Sbjct: 1067 GALGFSIEGPSQAQIECLDNGDGSADVWYLPTMPGEYAVHILCSDEDIPKSPFMADIKPA 1246

Query: 2406 SD-DARRLTVT--SLQETGLKVNQPASFAVQLNGA 2437
            +D DA ++      L+++G+  N+ A F V    A
Sbjct: 1247 ADFDAEKVIAKGPGLEKSGVAPNKWAEFTVDTKAA 1351

 Score = 55.5 bits (132), Expect(2) = 9e-20,   Method: Compositional matrix adjust.
 Identities = 72/286 (25%), Positives = 112/286 (39%), Gaps = 29/286 (10%)
 Frame = +3

Query: 2073 GGLGLSIEGPSKVDINCE----DMEDGTCKVTYCPTEPGTYIINIKFADKHVPGSPFTVK 2128
            G + +SI  P  V+  CE    +  + T    Y PT  G Y +NI FA+K +  SPFTV 
Sbjct: 180  GDVEVSILNPKGVEETCEVEFNNDRNLTYSCAYVPTMEGHYKVNILFANKVIAKSPFTVT 359

Query: 2129 VTGEGRMKESITRR----RQAPSIATIGSTCDLNLKIPGNWFQMV-----SAQERLTRTF 2179
            V G       +T       +   +AT  +  ++ +K  GN    V       ++   R  
Sbjct: 360  VEGAAGDASKVTASGPGLEKTGVVATKKTFFEVFVKGAGNGKVDVVILDPHGRKDNVRPK 539

Query: 2180 TRSSHTYTRTERTEISKTRGGETKREVRVEESTQVGGDPF----------PAVFGDFLGR 2229
             +S+     T   E      G     V    S Q+   PF           A +    G 
Sbjct: 540  VQSAPDKDATYLVEYVTIDQGLHSVNVFFAGS-QIPNSPFGVQVAPASNAKACYATGRGV 716

Query: 2230 E----RLGSFGSITRQQEGEASSQDMTAQVTSPSGKTEAAEI--VEGEDSAYSVRFVPQE 2283
            +    R+          +G A   ++  Q+  P G  E  ++  V  +   +   + P +
Sbjct: 717  QPRGVRVKDRADFYVHTKG-AGDGEVAVQIIGPGGVEEKCQLKKVPDQPEVWECVYNPSK 893

Query: 2284 MGPHTVTVKYRGQHVPGSPFQFTVGPLGEGGAHKVRAGGTGLERGV 2329
             G + + + +  QH+  SPF+  VGP  E    K+RA G GLE GV
Sbjct: 894  PGNYIINITFGDQHISKSPFKIEVGPYKES---KIRAYGPGLEGGV 1022

 Score = 95.5 bits (236), Expect = 3e-19,   Method: Compositional matrix adjust.
 Identities = 52/96 (54%), Positives = 63/96 (65%), Gaps = 4/96 (4%)
 Frame = +2

Query: 1100 VEGPCEAKIECQDNGDGSCAVSYLPTEPGEYTINILFAEAHIPGSPFKATIQPV--FDPS 1157
            +EGP +A+IEC DNGDGS  V YLPT PGEY ++IL ++  IP SPF A I+P   FD  
Sbjct: 1085 IEGPSQAQIECLDNGDGSADVWYLPTMPGEYAVHILCSDEDIPKSPFMADIKPAADFDAE 1264

Query: 1158 KVRASGPGLERGKAG--EAATFTVDCSEAGEAELTI 1191
            KV A GPGLE+      + A FTVD   AG+A L I
Sbjct: 1265 KVIAKGPGLEKSGVAPNKWAEFTVDTKAAGKAPLVI 1372

 Score = 65.5 bits (158), Expect(2) = 7e-19,   Method: Compositional matrix adjust.
 Identities = 58/179 (32%), Positives = 81/179 (45%), Gaps = 2/179 (1%)
 Frame = +3

Query: 211 DPNQPVQNAREAMQQADDWLGVPQVIAPEEIVDPNVDEHSVMTYL--SQFPKAKLKPGAP 268
           DP+    N R  +Q A D      V    E V  +   HSV  +   SQ P +   P   
Sbjct: 504 DPHGRKDNVRPKVQSAPDKDATYLV----EYVTIDQGLHSVNVFFAGSQIPNS---PFGV 662

Query: 269 VRSKQLNPKKAIAYGPGIEPQGNTVLQPAHFTVQTVDAGVGEVLVYIEDPEGHTEEAKVV 328
             +   N K   A G G++P+G  V   A F V T  AG GEV V I  P G  E+ ++ 
Sbjct: 663 QVAPASNAKACYATGRGVQPRGVRVKDRADFYVHTKGAGDGEVAVQIIGPGGVEEKCQLK 842

Query: 329 PNNDKDRTYAVSYVPKVAGLHKVTVLFAGQNIERSPFEVNVGMALGDANKVSARGPGLE 387
              D+   +   Y P   G + + + F  Q+I +SPF++ VG      +K+ A GPGLE
Sbjct: 843 KVPDQPEVWECVYNPSKPGNYIINITFGDQHISKSPFKIEVGPY--KESKIRAYGPGLE 1013

 Score = 48.9 bits (115), Expect(2) = 7e-19,   Method: Compositional matrix adjust.
 Identities = 30/91 (32%), Positives = 45/91 (49%), Gaps = 2/91 (2%)
 Frame = +2

Query: 425  VEVALEDKGDNTFRCTYRPVMEGPHTVHVAFAGAPITRSPFPVHVAEACNPNACR--ASG 482
             ++   D GD +    Y P M G + VH+  +   I +SPF   +  A + +A +  A G
Sbjct: 1103 AQIECLDNGDGSADVWYLPTMPGEYAVHILCSDEDIPKSPFMADIKPAADFDAEKVIAKG 1282

Query: 483  RGLQPKGVRVKEVADFKVFTKGAGSGELKVT 513
             GL+  GV   + A+F V TK AG   L +T
Sbjct: 1283 PGLEKSGVAPNKWAEFTVDTKAAGKAPLVIT 1375

 Score = 68.9 bits (167), Expect = 3e-11,   Method: Compositional matrix adjust.
 Identities = 75/304 (24%), Positives = 127/304 (41%), Gaps = 16/304 (5%)
 Frame = +3

Query: 2438 RGVIDARVHTPSGAVEECYVSELDSDK---HTIRFIPHENGVHSIDVKFNGAHIPGSPFK 2494
            +G ++  +  P G  E C V E ++D+   ++  ++P   G + +++ F    I  SPF 
Sbjct: 177  KGDVEVSILNPKGVEETCEV-EFNNDRNLTYSCAYVPTMEGHYKVNILFANKVIAKSPFT 353

Query: 2495 IRVGEQSQAGDPGLVSAYGPGLEGGTTGVSSE----FIVNTQNAGSGALSVTIDGP---- 2546
            + V  +  AGD   V+A GPGLE   TGV +     F V  + AG+G + V I  P    
Sbjct: 354  VTV--EGAAGDASKVTASGPGLE--KTGVVATKKTFFEVFVKGAGNGKVDVVILDPHGRK 521

Query: 2547 SKVQLDCRECPEG---HVVTYTPMAPGNYLIAIKYGGPQHIVGSPFKAKVTGPRLSGGHS 2603
              V+   +  P+    ++V Y  +  G + + + + G Q I  SPF  +V          
Sbjct: 522  DNVRPKVQSAPDKDATYLVEYVTIDQGLHSVNVFFAGSQ-IPNSPFGVQVA--------- 671

Query: 2604 LHETSTVLVETVTKXXXXXXXXXXXIPKFSSDASKVVTRGPGLSQAFVGQKNSFTVDCSK 2663
                                      P  ++ A     RG       V  +  F V    
Sbjct: 672  --------------------------PASNAKACYATGRGVQPRGVRVKDRADFYVHTKG 773

Query: 2664 AGTNMMMVGVHGPKTPCEEVYVKHMGNR--VYNVTYTVKEKGDYILIVKWGDESVPGSPF 2721
            AG   + V + GP    E+  +K + ++  V+   Y   + G+YI+ + +GD+ +  SPF
Sbjct: 774  AGDGEVAVQIIGPGGVEEKCQLKKVPDQPEVWECVYNPSKPGNYIINITFGDQHISKSPF 953

Query: 2722 KVNV 2725
            K+ V
Sbjct: 954  KIEV 965

 Score = 66.6 bits (161), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 34/68 (50%), Positives = 45/68 (66%), Gaps = 1/68 (1%)
 Frame = +2

Query: 1881 FTIVTKDAGE-GGLSLAVEGPSKAEITCKDNKDGTCTVSYLPTAPGDYSIIVRFDDKHIP 1939
            FT+ T   GE G L  ++EGPS+A+I C DN DG+  V YLPT PG+Y++ +   D+ IP
Sbjct: 1040 FTVETN--GETGALGFSIEGPSQAQIECLDNGDGSADVWYLPTMPGEYAVHILCSDEDIP 1213

Query: 1940 GSPFTAKI 1947
             SPF A I
Sbjct: 1214 KSPFMADI 1237

 Score = 62.8 bits (151), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 34/74 (45%), Positives = 45/74 (60%), Gaps = 2/74 (2%)
 Frame = +2

Query: 832  VKYTPPGAGHYTIMVLFANQEIPASPFHIKVDPS--HDASKVKAEGPGLSRTGVEVGKPT 889
            V Y P   G Y + +L ++++IP SPF   + P+   DA KV A+GPGL ++GV   K  
Sbjct: 1145 VWYLPTMPGEYAVHILCSDEDIPKSPFMADIKPAADFDAEKVIAKGPGLEKSGVAPNKWA 1324

Query: 890  HFTVLTKGAGKAKL 903
             FTV TK AGKA L
Sbjct: 1325 EFTVDTKAAGKAPL 1366

 Score = 60.5 bits (145), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 45/125 (36%), Positives = 55/125 (44%), Gaps = 3/125 (2%)
 Frame = +2

Query: 1359 PGLEGGLVNKANRFTVXXXXXXXXXXXXXXXXPSEAKMSCKDNKDGSCTVEYIPFTPGDY 1418
            PG  GG      RFTV                PS+A++ C DN DGS  V Y+P  PG+Y
Sbjct: 1007 PGRRGGAAE--GRFTVETNGETGALGFSIEG-PSQAQIECLDNGDGSADVWYLPTMPGEY 1177

Query: 1419 DVNITFGGQPIPGSPFRXXX--XXXXXXXXXXCSGPGL-GTGVRARVPQTFTVDCSQAGR 1475
             V+I    + IP SPF                  GPGL  +GV       FTVD   AG+
Sbjct: 1178 AVHILCSDEDIPKSPFMADIKPAADFDAEKVIAKGPGLEKSGVAPNKWAEFTVDTKAAGK 1357

Query: 1476 APLQV 1480
            APL +
Sbjct: 1358 APLVI 1372

 Score = 58.9 bits (141), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 42/116 (36%), Positives = 57/116 (49%), Gaps = 3/116 (2%)
 Frame = +2

Query: 1168 RGKAGEAATFTVDCS-EAGEAELTIEILSDAGVKAEVLIQNNADGTYHITYSPAFPGTYT 1226
            RG A E   FTV+ + E G    +IE  S    +A++   +N DG+  + Y P  PG Y 
Sbjct: 1016 RGGAAEG-RFTVETNGETGALGFSIEGPS----QAQIECLDNGDGSADVWYLPTMPGEYA 1180

Query: 1227 ITIKYGGHPIPKFPTRVHVQPAVDTSGIKV--SGPGVEPHGVLREVTTEFTVDARS 1280
            + I      IPK P    ++PA D    KV   GPG+E  GV      EFTVD ++
Sbjct: 1181 VHILCSDEDIPKSPFMADIKPAADFDAEKVIAKGPGLEKSGVAPNKWAEFTVDTKA 1348

 Score = 53.5 bits (127), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 39/121 (32%), Positives = 63/121 (52%), Gaps = 1/121 (0%)
 Frame = +2

Query: 298  HFTVQTVDAGVGEVLVYIEDPEGHTEEAKVVPNNDKDRTYAVSYVPKVAGLHKVTVLFAG 357
             FTV+T +   G +   IE P     +A++   ++ D +  V Y+P + G + V +L + 
Sbjct: 1037 RFTVET-NGETGALGFSIEGPS----QAQIECLDNGDGSADVWYLPTMPGEYAVHILCSD 1201

Query: 358  QNIERSPFEVNVGMALG-DANKVSARGPGLEPVGNVANKPTYFDIYTAGAGTGDVAVVIV 416
            ++I +SPF  ++  A   DA KV A+GPGLE  G   NK   F + T  AG   + +  +
Sbjct: 1202 EDIPKSPFMADIKPAADFDAEKVIAKGPGLEKSGVAPNKWAEFTVDTKAAGKAPLVITGM 1381

Query: 417  D 417
            D
Sbjct: 1382 D 1384

 Score = 53.1 bits (126), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 54/189 (28%), Positives = 76/189 (40%), Gaps = 3/189 (1%)
 Frame = +2

Query: 2486 AHIPGSPFKIRVGEQSQAGDPGLVSAYGPGLEGGTTGVSSEFIVNTQNAGSGALSVTIDG 2545
            AH+   P + R G      D GL +   PG  GG       F V T N  +GAL  +I+G
Sbjct: 932  AHLQ-KPLQDRGGPLXGEQDQGLWTR--PGRRGGA--AEGRFTVET-NGETGALGFSIEG 1093

Query: 2546 PSKVQLDCRECPEGHV-VTYTPMAPGNYLIAIKYGGPQHIVGSPFKAKVTGPRLSGGHSL 2604
            PS+ Q++C +  +G   V Y P  PG Y + I     + I  SPF A +           
Sbjct: 1094 PSQAQIECLDNGDGSADVWYLPTMPGEYAVHI-LCSDEDIPKSPFMADIK---------- 1240

Query: 2605 HETSTVLVETVTKXXXXXXXXXXXIPKFSSDASKVVTRGPGLSQAFVG--QKNSFTVDCS 2662
                                     P    DA KV+ +GPGL ++ V   +   FTVD  
Sbjct: 1241 -------------------------PAADFDAEKVIAKGPGLEKSGVAPNKWAEFTVDTK 1345

Query: 2663 KAGTNMMMV 2671
             AG   +++
Sbjct: 1346 AAGKAPLVI 1372

 Score = 45.1 bits (105), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 36/111 (32%), Positives = 50/111 (45%), Gaps = 5/111 (4%)
 Frame = +2

Query: 890  HFTVLTKGAGKAKLDVHFAGAAKGEAVRDFEIIDNHDYSYTVKYTAVQQGNMAVTVTYGG 949
             FTV T G   A        + +G +    E +DN D S  V Y     G  AV +    
Sbjct: 1037 RFTVETNGETGA-----LGFSIEGPSQAQIECLDNGDGSADVWYLPTMPGEYAVHILCSD 1201

Query: 950  DPVPKSPFVVNVAPPLDLSKVKV----QGL-NSKVAVGQEQAFSVNTRGAG 995
            + +PKSPF+ ++ P  D    KV     GL  S VA  +   F+V+T+ AG
Sbjct: 1202 EDIPKSPFMADIKPAADFDAEKVIAKGPGLEKSGVAPNKWAEFTVDTKAAG 1354

 Score = 43.5 bits (101), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 37/105 (35%), Positives = 48/105 (45%), Gaps = 4/105 (3%)
 Frame = +2

Query: 1274 FTVDARSLTATGGNHVTARVLNPSGAKTDTYVTDNGDGTYRVQYTAYEEGVHLVEVLYDE 1333
            FTV+    T   G  +      PS A+ +    DNGDG+  V Y     G + V +L  +
Sbjct: 1040 FTVETNGETGALGFSIE----GPSQAQIECL--DNGDGSADVWYLPTMPGEYAVHILCSD 1201

Query: 1334 VAVPKSPFRVGVTEGC--DPTRVRAFGPGLEGGLV--NKANRFTV 1374
              +PKSPF   +      D  +V A GPGLE   V  NK   FTV
Sbjct: 1202 EDIPKSPFMADIKPAADFDAEKVIAKGPGLEKSGVAPNKWAEFTV 1336

 Score = 43.1 bits (100), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 24/80 (30%), Positives = 39/80 (48%)
 Frame = +2

Query: 1689 AELDVDVVENHDGTFDIYYTAPEPGKYVITIRFGGEHIPNSPFHVLACDPLPHVEEPAEM 1748
            ++  ++ ++N DG+ D++Y    PG+Y + I    E IP SPF     D  P  +  AE 
Sbjct: 1097 SQAQIECLDNGDGSADVWYLPTMPGEYAVHILCSDEDIPKSPFMA---DIKPAADFDAEK 1267

Query: 1749 LQMRQPYAPLRPGTCPTHWA 1768
            +  + P    + G  P  WA
Sbjct: 1268 VIAKGP-GLEKSGVAPNKWA 1324

 Score = 42.7 bits (99), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 39/113 (34%), Positives = 51/113 (45%), Gaps = 9/113 (7%)
 Frame = +2

Query: 1792 FTVQK----GELTGEVRMPSGKTARPNITDNKDGTITVRYAPTEKGLHQMGIKYDGNHIP 1847
            FTV+     G L   +  PS   A+    DN DG+  V Y PT  G + + I      IP
Sbjct: 1040 FTVETNGETGALGFSIEGPS--QAQIECLDNGDGSADVWYLPTMPGEYAVHILCSDEDIP 1213

Query: 1848 GSPLQFYVD---AINSRHVSAYGPGLSHGMV--NKPATFTIVTKDAGEGGLSL 1895
             SP    +      ++  V A GPGL    V  NK A FT+ TK AG+  L +
Sbjct: 1214 KSPFMADIKPAADFDAEKVIAKGPGLEKSGVAPNKWAEFTVDTKAAGKAPLVI 1372

 Score = 42.0 bits (97), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 33/103 (32%), Positives = 47/103 (45%), Gaps = 2/103 (1%)
 Frame = +2

Query: 1971 TEGDLSQLTASIRAPSGNEEPCLLKRLPNRHIGISFTPKEVGEHVVSVRKSGKHVTNSPF 2030
            T G+   L  SI  PS  +  CL     +    + + P   GE+ V +  S + +  SPF
Sbjct: 1052 TNGETGALGFSIEGPSQAQIECLDNG--DGSADVWYLPTMPGEYAVHILCSDEDIPKSPF 1225

Query: 2031 KILVGPSEIGDASKVRVWGKGLSEGQTF--QVAEFIVDTRNAG 2071
               + P+   DA KV   G GL +      + AEF VDT+ AG
Sbjct: 1226 MADIKPAADFDAEKVIAKGPGLEKSGVAPNKWAEFTVDTKAAG 1354

 Score = 41.6 bits (96), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 38/125 (30%), Positives = 58/125 (46%), Gaps = 2/125 (1%)
 Frame = +2

Query: 2228 GRERLGSFGSITRQQEGEASSQDMTAQVTSPSGKTEAAEIVEGEDSAYSVRFVPQEMGPH 2287
            GR    + G  T +  GE  +  +   +  PS      E ++  D +  V ++P   G +
Sbjct: 1010 GRRGGAAEGRFTVETNGETGA--LGFSIEGPS--QAQIECLDNGDGSADVWYLPTMPGEY 1177

Query: 2288 TVTVKYRGQHVPGSPFQFTVGPLGEGGAHKVRAGGTGLER-GVA-GVPAEFSIWTREAGA 2345
             V +    + +P SPF   + P  +  A KV A G GLE+ GVA    AEF++ T+ AG 
Sbjct: 1178 AVHILCSDEDIPKSPFMADIKPAADFDAEKVIAKGPGLEKSGVAPNKWAEFTVDTKAAGK 1357

Query: 2346 GGLSI 2350
              L I
Sbjct: 1358 APLVI 1372

 Score = 37.0 bits (84), Expect = 0.100,   Method: Composition-based stats.
 Identities = 16/35 (45%), Positives = 22/35 (62%)
 Frame = +1

Query: 764 HPERVKVYGPGVEKTGLKANEPTYFTVDCSEAGQG 798
           +P RV+ YGPG+E  G +   P  FTV+   AG+G
Sbjct: 79  NPARVRAYGPGLEPKGNQVGAPARFTVETFSAGRG 183

 Score = 34.3 bits (77), Expect = 0.78,   Method: Composition-based stats.
 Identities = 15/39 (38%), Positives = 22/39 (56%)
 Frame = +1

Query: 1536 PSHDASKVRASGPGLNASGIPASLPVEFTIDARDAGQGL 1574
            P  + ++VRA GPGL   G     P  FT++   AG+G+
Sbjct: 70   PRLNPARVRAYGPGLEPKGNQVGAPARFTVETFSAGRGM 186

 Score = 32.7 bits (73), Expect = 2.3,   Method: Composition-based stats.
 Identities = 20/50 (40%), Positives = 26/50 (52%), Gaps = 2/50 (4%)
 Frame = +1

Query: 2490 GSPFKIRVGEQSQAGDPGLVSAYGPGLE--GGTTGVSSEFIVNTQNAGSG 2537
            G+P + R+       +P  V AYGPGLE  G   G  + F V T +AG G
Sbjct: 55   GAPLRPRL-------NPARVRAYGPGLEPKGNQVGAPARFTVETFSAGRG 183
>17351
          Length = 654

 Score =  258 bits (658), Expect = 3e-68,   Method: Compositional matrix adjust.
 Identities = 123/217 (56%), Positives = 161/217 (74%)
 Frame = -1

Query: 2247 SSQDMTAQVTSPSGKTEAAEIVEGEDSAYSVRFVPQEMGPHTVTVKYRGQHVPGSPFQFT 2306
            +S D+ A VTSPS  TE AEI E ED  YSV FVP+E+G HTV+V+Y   H+PGSPFQFT
Sbjct: 651  TSFDLAACVTSPSNVTEDAEIQEIEDGLYSVHFVPKELGVHTVSVRYSEMHIPGSPFQFT 472

Query: 2307 VGPLGEGGAHKVRAGGTGLERGVAGVPAEFSIWTREAGAGGLSIAVEGPSKAEIAFEDRK 2366
            VGPL + G+H V+AGG+GLERGV G PAEF++WTREAG G L+I+VEGPSKA+I F+DRK
Sbjct: 471  VGPLRDSGSHLVKAGGSGLERGVVGEPAEFNVWTREAGGGSLAISVEGPSKADIEFKDRK 292

Query: 2367 DGSCGVSYVVQEPGDYEVSIKFNDEHIPDSPFVVPVASLSDDARRLTVTSLQETGLKVNQ 2426
            DGSC VSY V EPG+Y V +KFND HIPDSPF V ++  + DA +L V    +  ++ + 
Sbjct: 291  DGSCDVSYKVTEPGEYRVGLKFNDRHIPDSPFKVYISPDAGDAHKLEVQQFPQGNIQADA 112

Query: 2427 PASFAVQLNGARGVIDARVHTPSGAVEECYVSELDSD 2463
            P  F V+ NGA+G +DA++  PSG  ++C++  +D +
Sbjct: 111  PYQFMVRKNGAKGELDAKIVAPSGTDDDCFIQAIDGE 1

 Score =  145 bits (367), Expect = 2e-34,   Method: Compositional matrix adjust.
 Identities = 81/211 (38%), Positives = 119/211 (56%), Gaps = 11/211 (5%)
 Frame = -1

Query: 1798 ELTGEVRMPSGKTARPNITDNKDGTITVRYAPTEKGLHQMGIKYDGNHIPGSPLQFYVDA 1857
            +L   V  PS  T    I + +DG  +V + P E G+H + ++Y   HIPGSP QF V  
Sbjct: 642  DLAACVTSPSNVTEDAEIQEIEDGLYSVHFVPKELGVHTVSVRYSEMHIPGSPFQFTVGP 463

Query: 1858 IN---SRHVSAYGPGLSHGMVNKPATFTIVTKDAGEGGLSLAVEGPSKAEITCKDNKDGT 1914
            +    S  V A G GL  G+V +PA F + T++AG G L+++VEGPSKA+I  KD KDG+
Sbjct: 462  LRDSGSHLVKAGGSGLERGVVGEPAEFNVWTREAGGGSLAISVEGPSKADIEFKDRKDGS 283

Query: 1915 CTVSYLPTAPGDYSIIVRFDDKHIPGSPFTAKITGD-------DSMRTSQLNVGTSTDVS 1967
            C VSY  T PG+Y + ++F+D+HIP SPF   I+ D       +  +  Q N+       
Sbjct: 282  CDVSYKVTEPGEYRVGLKFNDRHIPDSPFKVYISPDAGDAHKLEVQQFPQGNIQADAPYQ 103

Query: 1968 LKITE-GDLSQLTASIRAPSGNEEPCLLKRL 1997
              + + G   +L A I APSG ++ C ++ +
Sbjct: 102  FMVRKNGAKGELDAKIVAPSGTDDDCFIQAI 10

 Score =  129 bits (324), Expect = 2e-29,   Method: Compositional matrix adjust.
 Identities = 66/153 (43%), Positives = 91/153 (59%)
 Frame = -1

Query: 1978 LTASIRAPSGNEEPCLLKRLPNRHIGISFTPKEVGEHVVSVRKSGKHVTNSPFKILVGPS 2037
            L A + +PS   E   ++ + +    + F PKE+G H VSVR S  H+  SPF+  VGP 
Sbjct: 639  LAACVTSPSNVTEDAEIQEIEDGLYSVHFVPKELGVHTVSVRYSEMHIPGSPFQFTVGPL 460

Query: 2038 EIGDASKVRVWGKGLSEGQTFQVAEFIVDTRNAGYGGLGLSIEGPSKVDINCEDMEDGTC 2097
                +  V+  G GL  G   + AEF V TR AG G L +S+EGPSK DI  +D +DG+C
Sbjct: 459  RDSGSHLVKAGGSGLERGVVGEPAEFNVWTREAGGGSLAISVEGPSKADIEFKDRKDGSC 280

Query: 2098 KVTYCPTEPGTYIINIKFADKHVPGSPFTVKVT 2130
             V+Y  TEPG Y + +KF D+H+P SPF V ++
Sbjct: 279  DVSYKVTEPGEYRVGLKFNDRHIPDSPFKVYIS 181

 Score =  119 bits (297), Expect = 2e-26,   Method: Compositional matrix adjust.
 Identities = 78/205 (38%), Positives = 109/205 (53%), Gaps = 4/205 (1%)
 Frame = -1

Query: 507 SGELKVTVKGPKGTEEPVKVREAGDGVFECEYYPVVPGKYVVTITWGGYAIPRSPFEVQV 566
           S +L   V  P    E  +++E  DG++   + P   G + V++ +    IP SPF+  V
Sbjct: 648 SFDLAACVTSPSNVTEDAEIQEIEDGLYSVHFVPKELGVHTVSVRYSEMHIPGSPFQFTV 469

Query: 567 SP--EAGAQKVRAWGPGLETGQVGKSADFVVEAIGTEVGTLGFSIEGPSQAKIECDDKGD 624
            P  ++G+  V+A G GLE G VG+ A+F V       G+L  S+EGPS+A IE  D+ D
Sbjct: 468 GPLRDSGSHLVKAGGSGLERGVVGEPAEFNVWTREAGGGSLAISVEGPSKADIEFKDRKD 289

Query: 625 GSCDVRYWPTEPGEYAVHVICDDEDIRDSPFIAHIQPAPPDCFPDKVKAFGPGLEPTGCI 684
           GSCDV Y  TEPGEY V +  +D  I DSPF  +I P   D    +V+ F     P G I
Sbjct: 288 GSCDVSYKVTEPGEYRVGLKFNDRHIPDSPFKVYISPDAGDAHKLEVQQF-----PQGNI 124

Query: 685 -VDRPAEFTIDARAA-GKGDLKLYA 707
             D P +F +    A G+ D K+ A
Sbjct: 123 QADAPYQFMVRKNGAKGELDAKIVA 49

 Score =  107 bits (267), Expect = 6e-23,   Method: Compositional matrix adjust.
 Identities = 60/163 (36%), Positives = 96/163 (58%), Gaps = 1/163 (0%)
 Frame = -1

Query: 2443 ARVHTPSGAVEECYVSELDSDKHTIRFIPHENGVHSIDVKFNGAHIPGSPFKIRVGEQSQ 2502
            A V +PS   E+  + E++   +++ F+P E GVH++ V+++  HIPGSPF+  VG    
Sbjct: 633  ACVTSPSNVTEDAEIQEIEDGLYSVHFVPKELGVHTVSVRYSEMHIPGSPFQFTVGPLRD 454

Query: 2503 AGDPGLVSAYGPGLEGGTTGVSSEFIVNTQNAGSGALSVTIDGPSKVQLDCRECPEGHV- 2561
            +G   LV A G GLE G  G  +EF V T+ AG G+L+++++GPSK  ++ ++  +G   
Sbjct: 453  SGS-HLVKAGGSGLERGVVGEPAEFNVWTREAGGGSLAISVEGPSKADIEFKDRKDGSCD 277

Query: 2562 VTYTPMAPGNYLIAIKYGGPQHIVGSPFKAKVTGPRLSGGHSL 2604
            V+Y    PG Y + +K+   +HI  SPFK  ++ P     H L
Sbjct: 276  VSYKVTEPGEYRVGLKFND-RHIPDSPFKVYIS-PDAGDAHKL 154

 Score =  100 bits (248), Expect = 1e-20,   Method: Compositional matrix adjust.
 Identities = 67/201 (33%), Positives = 108/201 (53%), Gaps = 4/201 (1%)
 Frame = -1

Query: 1109 ECQDNGDGSCAVSYLPTEPGEYTINILFAEAHIPGSPFKATIQPVFDPSK--VRASGPGL 1166
            E Q+  DG  +V ++P E G +T+++ ++E HIPGSPF+ T+ P+ D     V+A G GL
Sbjct: 594  EIQEIEDGLYSVHFVPKELGVHTVSVRYSEMHIPGSPFQFTVGPLRDSGSHLVKAGGSGL 415

Query: 1167 ERGKAGEAATFTVDCSEAGEAELTIEILSDAGVKAEVLIQNNADGTYHITYSPAFPGTYT 1226
            ERG  GE A F V   EAG   L I +  +   KA++  ++  DG+  ++Y    PG Y 
Sbjct: 414  ERGVVGEPAEFNVWTREAGGGSLAISV--EGPSKADIEFKDRKDGSCDVSYKVTEPGEYR 241

Query: 1227 ITIKYGGHPIPKFPTRVHVQP-AVDTSGIKVSGPGVEPHGVLR-EVTTEFTVDARSLTAT 1284
            + +K+    IP  P +V++ P A D   ++V      P G ++ +   +F V  R   A 
Sbjct: 240  VGLKFNDRHIPDSPFKVYISPDAGDAHKLEVQQ---FPQGNIQADAPYQFMV--RKNGAK 76

Query: 1285 GGNHVTARVLNPSGAKTDTYV 1305
            G   + A+++ PSG   D ++
Sbjct: 75   G--ELDAKIVAPSGTDDDCFI 19

 Score = 96.3 bits (238), Expect = 2e-19,   Method: Compositional matrix adjust.
 Identities = 57/129 (44%), Positives = 73/129 (56%), Gaps = 2/129 (1%)
 Frame = -1

Query: 1026 AVRYMPPEEGPYKVDITYDGHPVPGSPFAVE-GVLPPDPSK-VCAYGPGLKGGLVGTPAP 1083
            +V ++P E G + V + Y    +PGSPF    G L    S  V A G GL+ G+VG PA 
Sbjct: 564  SVHFVPKELGVHTVSVRYSEMHIPGSPFQFTVGPLRDSGSHLVKAGGSGLERGVVGEPAE 385

Query: 1084 FSIDTKXXXXXXXXXXVEGPCEAKIECQDNGDGSCAVSYLPTEPGEYTINILFAEAHIPG 1143
            F++ T+          VEGP +A IE +D  DGSC VSY  TEPGEY + + F + HIP 
Sbjct: 384  FNVWTREAGGGSLAISVEGPSKADIEFKDRKDGSCDVSYKVTEPGEYRVGLKFNDRHIPD 205

Query: 1144 SPFKATIQP 1152
            SPFK  I P
Sbjct: 204  SPFKVYISP 178

 Score = 94.7 bits (234), Expect = 5e-19,   Method: Compositional matrix adjust.
 Identities = 62/170 (36%), Positives = 92/170 (54%), Gaps = 5/170 (2%)
 Frame = -1

Query: 1478 LQVAVLGPTGVAEPVEVRDNGDGTHTVHYTPATDGPYTVAVKYADQEVPRSPFKIKVLPS 1537
            L   V  P+ V E  E+++  DG ++VH+ P   G +TV+V+Y++  +P SPF+  V P 
Sbjct: 639  LAACVTSPSNVTEDAEIQEIEDGLYSVHFVPKELGVHTVSVRYSEMHIPGSPFQFTVGPL 460

Query: 1538 HDASK--VRASGPGLNASGIPASLPVEFTIDARDAGQGLLTVQILDPEGKPKKANI--RD 1593
             D+    V+A G GL    +    P EF +  R+AG G L + +   EG P KA+I  +D
Sbjct: 459  RDSGSHLVKAGGSGLERGVV--GEPAEFNVWTREAGGGSLAISV---EG-PSKADIEFKD 298

Query: 1594 NGDGTYTVSYLPDMSGRYTITIKYGGDEIPYSPFRIHALP-TGDASKCLV 1642
              DG+  VSY     G Y + +K+    IP SPF+++  P  GDA K  V
Sbjct: 297  RKDGSCDVSYKVTEPGEYRVGLKFNDRHIPDSPFKVYISPDAGDAHKLEV 148

 Score = 89.4 bits (220), Expect = 2e-17,   Method: Compositional matrix adjust.
 Identities = 55/149 (36%), Positives = 72/149 (48%), Gaps = 2/149 (1%)
 Frame = -1

Query: 1289 VTARVLNPSGAKTDTYVTDNGDGTYRVQYTAYEEGVHLVEVLYDEVAVPKSPFR--VGVT 1346
            + A V +PS    D  + +  DG Y V +   E GVH V V Y E+ +P SPF+  VG  
Sbjct: 639  LAACVTSPSNVTEDAEIQEIEDGLYSVHFVPKELGVHTVSVRYSEMHIPGSPFQFTVGPL 460

Query: 1347 EGCDPTRVRAFGPGLEGGLVNKANRFTVXXXXXXXXXXXXXXXXPSEAKMSCKDNKDGSC 1406
                   V+A G GLE G+V +   F V                PS+A +  KD KDGSC
Sbjct: 459  RDSGSHLVKAGGSGLERGVVGEPAEFNVWTREAGGGSLAISVEGPSKADIEFKDRKDGSC 280

Query: 1407 TVEYIPFTPGDYDVNITFGGQPIPGSPFR 1435
             V Y    PG+Y V + F  + IP SPF+
Sbjct: 279  DVSYKVTEPGEYRVGLKFNDRHIPDSPFK 193

 Score = 85.1 bits (209), Expect = 3e-16,   Method: Compositional matrix adjust.
 Identities = 52/159 (32%), Positives = 80/159 (50%)
 Frame = -1

Query: 1575 LTVQILDPEGKPKKANIRDNGDGTYTVSYLPDMSGRYTITIKYGGDEIPYSPFRIHALPT 1634
            L   +  P    + A I++  DG Y+V ++P   G +T++++Y    IP SPF+    P 
Sbjct: 639  LAACVTSPSNVTEDAEIQEIEDGLYSVHFVPKELGVHTVSVRYSEMHIPGSPFQFTVGPL 460

Query: 1635 GDASKCLVTVSIGGHGLGACLGPRIQIGEETVITVDAKAAGKGKVTCTVSTPDGAELDVD 1694
             D+   LV    GG GL      R  +GE     V  + AG G +  +V  P  A  D++
Sbjct: 459  RDSGSHLVKA--GGSGL-----ERGVVGEPAEFNVWTREAGGGSLAISVEGPSKA--DIE 307

Query: 1695 VVENHDGTFDIYYTAPEPGKYVITIRFGGEHIPNSPFHV 1733
              +  DG+ D+ Y   EPG+Y + ++F   HIP+SPF V
Sbjct: 306  FKDRKDGSCDVSYKVTEPGEYRVGLKFNDRHIPDSPFKV 190

 Score = 84.0 bits (206), Expect = 8e-16,   Method: Compositional matrix adjust.
 Identities = 60/191 (31%), Positives = 91/191 (47%), Gaps = 3/191 (1%)
 Frame = -1

Query: 830  FTVKYTPPGAGHYTIMVLFANQEIPASPFHIKVDPSHDASK--VKAEGPGLSRTGVEVGK 887
            ++V + P   G +T+ V ++   IP SPF   V P  D+    VKA G GL R GV VG+
Sbjct: 567  YSVHFVPKELGVHTVSVRYSEMHIPGSPFQFTVGPLRDSGSHLVKAGGSGLER-GV-VGE 394

Query: 888  PTHFTVLTKGAGKAKLDVHFAGAAKGEAVRDFEIIDNHDYSYTVKYTAVQQGNMAVTVTY 947
            P  F V T+ AG   L +   G +K     D E  D  D S  V Y   + G   V + +
Sbjct: 393  PAEFNVWTREAGGGSLAISVEGPSKA----DIEFKDRKDGSCDVSYKVTEPGEYRVGLKF 226

Query: 948  GGDPVPKSPFVVNVAPPL-DLSKVKVQGLNSKVAVGQEQAFSVNTRGAGGQGQLDVRMTS 1006
                +P SPF V ++P   D  K++VQ    +  +  +  +    R  G +G+LD ++ +
Sbjct: 225  NDRHIPDSPFKVYISPDAGDAHKLEVQQF-PQGNIQADAPYQFMVRKNGAKGELDAKIVA 49

Query: 1007 PSRRPIPCKLE 1017
            PS     C ++
Sbjct: 48   PSGTDDDCFIQ 16

 Score = 74.7 bits (182), Expect = 4e-13,   Method: Compositional matrix adjust.
 Identities = 62/212 (29%), Positives = 105/212 (49%), Gaps = 4/212 (1%)
 Frame = -1

Query: 315 IEDPEGHTEEAKVVPNNDKDRTYAVSYVPKVAGLHKVTVLFAGQNIERSPFEVNVG-MAL 373
           +  P   TE+A++     +D  Y+V +VPK  G+H V+V ++  +I  SPF+  VG +  
Sbjct: 627 VTSPSNVTEDAEI--QEIEDGLYSVHFVPKELGVHTVSVRYSEMHIPGSPFQFTVGPLRD 454

Query: 374 GDANKVSARGPGLEPVGNVANKPTYFDIYTAGAGTGDVAVVIVDPQGRRDTVEVALEDKG 433
             ++ V A G GLE    V  +P  F+++T  AG G +A+ +  P       ++  +D+ 
Sbjct: 453 SGSHLVKAGGSGLER--GVVGEPAEFNVWTREAGGGSLAISVEGPS----KADIEFKDRK 292

Query: 434 DNTFRCTYRPVMEGPHTVHVAFAGAPITRSPFPVHVAEACNPNACRASGRGLQ--PKG-V 490
           D +   +Y+    G + V + F    I  SPF V+++    P+A  A    +Q  P+G +
Sbjct: 291 DGSCDVSYKVTEPGEYRVGLKFNDRHIPDSPFKVYIS----PDAGDAHKLEVQQFPQGNI 124

Query: 491 RVKEVADFKVFTKGAGSGELKVTVKGPKGTEE 522
           +      F V   GA  GEL   +  P GT++
Sbjct: 123 QADAPYQFMVRKNGA-KGELDAKIVAPSGTDD 31

 Score = 66.6 bits (161), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 56/186 (30%), Positives = 88/186 (47%), Gaps = 5/186 (2%)
 Frame = -1

Query: 724 DGTFRCSYVPTKPIKHTIIVSWGGVNVPKSPFRVNVG----EGSHPERVKVYGPGVEKTG 779
           DG +   +VP +   HT+ V +  +++P SPF+  VG     GSH   VK  G G+E+  
Sbjct: 576 DGLYSVHFVPKELGVHTVSVRYSEMHIPGSPFQFTVGPLRDSGSH--LVKAGGSGLERGV 403

Query: 780 LKANEPTYFTVDCSEAGQGDVSIGIKCAPGVVGPVEAXXXXXXXXXXXXTFTVKYTPPGA 839
           +   EP  F V   EAG G ++I ++      GP +A              + K T P  
Sbjct: 402 V--GEPAEFNVWTREAGGGSLAISVE------GPSKADIEFKDRKDGSCDVSYKVTEP-- 253

Query: 840 GHYTIMVLFANQEIPASPFHIKVDP-SHDASKVKAEGPGLSRTGVEVGKPTHFTVLTKGA 898
           G Y + + F ++ IP SPF + + P + DA K++ +     +  ++   P  F V   GA
Sbjct: 252 GEYRVGLKFNDRHIPDSPFKVYISPDAGDAHKLEVQ--QFPQGNIQADAPYQFMVRKNGA 79

Query: 899 GKAKLD 904
            K +LD
Sbjct: 78  -KGELD 64

 Score = 63.5 bits (153), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 56/209 (26%), Positives = 96/209 (45%), Gaps = 12/209 (5%)
 Frame = -1

Query: 1893 LSLAVEGPSKA--EITCKDNKDGTCTVSYLPTAPGDYSIIVRFDDKHIPGSPFTAKI--- 1947
            L+  V  PS    +   ++ +DG  +V ++P   G +++ VR+ + HIPGSPF   +   
Sbjct: 639  LAACVTSPSNVTEDAEIQEIEDGLYSVHFVPKELGVHTVSVRYSEMHIPGSPFQFTVGPL 460

Query: 1948 --TGDDSMRT--SQLN---VGTSTDVSLKITEGDLSQLTASIRAPSGNEEPCLLKRLPNR 2000
              +G   ++   S L    VG   + ++   E     L  S+  PS  +     K   + 
Sbjct: 459  RDSGSHLVKAGGSGLERGVVGEPAEFNVWTREAGGGSLAISVEGPSKAD--IEFKDRKDG 286

Query: 2001 HIGISFTPKEVGEHVVSVRKSGKHVTNSPFKILVGPSEIGDASKVRVWGKGLSEGQTFQV 2060
               +S+   E GE+ V ++ + +H+ +SPFK+ + P + GDA K+ V        Q    
Sbjct: 285  SCDVSYKVTEPGEYRVGLKFNDRHIPDSPFKVYISP-DAGDAHKLEVQQFPQGNIQADAP 109

Query: 2061 AEFIVDTRNAGYGGLGLSIEGPSKVDINC 2089
             +F+V  +N   G L   I  PS  D +C
Sbjct: 108  YQFMV-RKNGAKGELDAKIVAPSGTDDDC 25

 Score = 62.8 bits (151), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 49/161 (30%), Positives = 76/161 (47%), Gaps = 2/161 (1%)
 Frame = -1

Query: 1188 ELTIEILSDAGVKAEVLIQNNADGTYHITYSPAFPGTYTITIKYGGHPIPKFPTRVHVQP 1247
            +L   + S + V  +  IQ   DG Y + + P   G +T++++Y    IP  P +  V P
Sbjct: 642  DLAACVTSPSNVTEDAEIQEIEDGLYSVHFVPKELGVHTVSVRYSEMHIPGSPFQFTVGP 463

Query: 1248 AVDTSG--IKVSGPGVEPHGVLREVTTEFTVDARSLTATGGNHVTARVLNPSGAKTDTYV 1305
              D+    +K  G G+E  GV+ E   EF V  R     GG  +   V  PS  K D   
Sbjct: 462  LRDSGSHLVKAGGSGLE-RGVVGE-PAEFNVWTRE---AGGGSLAISVEGPS--KADIEF 304

Query: 1306 TDNGDGTYRVQYTAYEEGVHLVEVLYDEVAVPKSPFRVGVT 1346
             D  DG+  V Y   E G + V + +++  +P SPF+V ++
Sbjct: 303  KDRKDGSCDVSYKVTEPGEYRVGLKFNDRHIPDSPFKVYIS 181

 Score = 56.2 bits (134), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 50/190 (26%), Positives = 78/190 (41%), Gaps = 3/190 (1%)
 Frame = -1

Query: 2539 LSVTIDGPSKVQLDC--RECPEG-HVVTYTPMAPGNYLIAIKYGGPQHIVGSPFKAKVTG 2595
            L+  +  PS V  D   +E  +G + V + P   G + ++++Y    HI GSPF+  V  
Sbjct: 639  LAACVTSPSNVTEDAEIQEIEDGLYSVHFVPKELGVHTVSVRYS-EMHIPGSPFQFTVGP 463

Query: 2596 PRLSGGHSLHETSTVLVETVTKXXXXXXXXXXXIPKFSSDASKVVTRGPGLSQAFVGQKN 2655
             R SG H                                    V   G GL +  VG+  
Sbjct: 462  LRDSGSH-----------------------------------LVKAGGSGLERGVVGEPA 388

Query: 2656 SFTVDCSKAGTNMMMVGVHGPKTPCEEVYVKHMGNRVYNVTYTVKEKGDYILIVKWGDES 2715
             F V   +AG   + + V GP     ++  K   +   +V+Y V E G+Y + +K+ D  
Sbjct: 387  EFNVWTREAGGGSLAISVEGPSKA--DIEFKDRKDGSCDVSYKVTEPGEYRVGLKFNDRH 214

Query: 2716 VPGSPFKVNV 2725
            +P SPFKV +
Sbjct: 213  IPDSPFKVYI 184

 Score = 53.9 bits (128), Expect = 8e-07,   Method: Compositional matrix adjust.
 Identities = 51/170 (30%), Positives = 77/170 (45%), Gaps = 3/170 (1%)
 Frame = -1

Query: 624 DGSCDVRYWPTEPGEYAVHVICDDEDIRDSPFIAHIQPAPPDCFPDKVKAFGPGLEPTGC 683
           DG   V + P E G + V V   +  I  SPF   + P   D     VKA G GLE    
Sbjct: 576 DGLYSVHFVPKELGVHTVSVRYSEMHIPGSPFQFTVGPLR-DSGSHLVKAGGSGLERG-- 406

Query: 684 IVDRPAEFTIDARAAGKGDLKLYAQDADGCPIDIKVIPNGDGTFRCSYVPTKPIKHTIIV 743
           +V  PAEF +  R AG G L +  +      I+ K     DG+   SY  T+P ++ + +
Sbjct: 405 VVGEPAEFNVWTREAGGGSLAISVEGPSKADIEFK--DRKDGSCDVSYKVTEPGEYRVGL 232

Query: 744 SWGGVNVPKSPFRVNV---GEGSHPERVKVYGPGVEKTGLKANEPTYFTV 790
            +   ++P SPF+V +      +H   V+ +  G     ++A+ P  F V
Sbjct: 231 KFNDRHIPDSPFKVYISPDAGDAHKLEVQQFPQG----NIQADAPYQFMV 94
>29446
          Length = 1445

 Score =  204 bits (518), Expect = 5e-52,   Method: Composition-based stats.
 Identities = 100/154 (64%), Positives = 121/154 (78%), Gaps = 2/154 (1%)
 Frame = +3

Query: 24   STEKDLAEDAPWKKIQQNTFTRWCNEHLKCVGKRLTDLQRDLSDGLRLIALLEVLSQKRM 83
            STE++LAEDA WK IQ+NTFTRW NEHL+ V K + DL+ D SDGLRL+AL+EVLS K+ 
Sbjct: 957  STERELAEDAQWKIIQKNTFTRWANEHLRTVNKAIADLESDFSDGLRLVALIEVLSGKK- 1133

Query: 84   YRKFHPRPNFRQMKLENVSVALEFLE-REHIKLVSIDSKAIVDGNLKLILGLIWTLILHY 142
            ++  + RPNFR  KLENV++ L+FLE  E I++V+IDS  IVD  LKLILGLIWTLILHY
Sbjct: 1134 FKHVNKRPNFRTQKLENVTLTLKFLEDDEGIRIVNIDSTDIVDKKLKLILGLIWTLILHY 1313

Query: 143  SISMPMWEDEDDEDAR-KQTPKQRLLGWIQNKVP 175
            SISMPMWE E+   +    TPKQRLL WIQ+KVP
Sbjct: 1314 SISMPMWEGEEPTPSEGGPTPKQRLLNWIQSKVP 1415
>19277
          Length = 511

 Score =  180 bits (456), Expect(2) = 4e-51,   Method: Compositional matrix adjust.
 Identities = 86/132 (65%), Positives = 105/132 (79%), Gaps = 2/132 (1%)
 Frame = +2

Query: 2034 VGPSEIGDASKVRVWGKGLSEGQTFQVAEFIVDTRNAGYGGLGLSIEGPSKVDINCEDME 2093
            VG SE+G+ASKV+V G GL+EG   +V EF+VDTR AGYGG+ LSIEGPSK DI C D E
Sbjct: 77   VGESELGNASKVKVSGDGLTEGMANEVNEFVVDTREAGYGGMSLSIEGPSKADIECHDNE 256

Query: 2094 DGTCKVTYCPTEPGTYIINIKFADKHVPGSPFTVKVTGE--GRMKESITRRRQAPSIATI 2151
            DGTC+VTY PTEPGTYIINIKFAD+HVPGSP++VK+ GE   ++ E ITR + A  +  +
Sbjct: 257  DGTCRVTYKPTEPGTYIINIKFADQHVPGSPYSVKIGGEPSTKITERITRHKAAADVTHV 436

Query: 2152 GSTCDLNLKIPG 2163
            GS C+L+LKIPG
Sbjct: 437  GSQCELSLKIPG 472

 Score = 42.4 bits (98), Expect(2) = 4e-51,   Method: Composition-based stats.
 Identities = 17/28 (60%), Positives = 23/28 (82%)
 Frame = +1

Query: 2008 PKEVGEHVVSVRKSGKHVTNSPFKILVG 2035
            P+E GEH+V+V ++GKH+ NSPFKI  G
Sbjct: 1    PRETGEHLVNVYRNGKHIANSPFKICRG 84

 Score =  114 bits (284), Expect = 8e-25,   Method: Compositional matrix adjust.
 Identities = 55/123 (44%), Positives = 81/123 (65%), Gaps = 11/123 (8%)
 Frame = +2

Query: 1859 NSRHVSAYGPGLSHGMVNKPATFTIVTKDAGEGGLSLAVEGPSKAEITCKDNKDGTCTVS 1918
            N+  V   G GL+ GM N+   F + T++AG GG+SL++EGPSKA+I C DN+DGTC V+
Sbjct: 98   NASKVKVSGDGLTEGMANEVNEFVVDTREAGYGGMSLSIEGPSKADIECHDNEDGTCRVT 277

Query: 1919 YLPTAPGDYSIIVRFDDKHIPGSPFTAKITGDDSMRTSQ-----------LNVGTSTDVS 1967
            Y PT PG Y I ++F D+H+PGSP++ KI G+ S + ++            +VG+  ++S
Sbjct: 278  YKPTEPGTYIINIKFADQHVPGSPYSVKIGGEPSTKITERITRHKAAADVTHVGSQCELS 457

Query: 1968 LKI 1970
            LKI
Sbjct: 458  LKI 466

 Score = 95.9 bits (237), Expect(2) = 4e-22,   Method: Compositional matrix adjust.
 Identities = 47/97 (48%), Positives = 65/97 (67%)
 Frame = +2

Query: 2306 TVGPLGEGGAHKVRAGGTGLERGVAGVPAEFSIWTREAGAGGLSIAVEGPSKAEIAFEDR 2365
            +VG    G A KV+  G GL  G+A    EF + TREAG GG+S+++EGPSKA+I   D 
Sbjct: 74   SVGESELGNASKVKVSGDGLTEGMANEVNEFVVDTREAGYGGMSLSIEGPSKADIECHDN 253

Query: 2366 KDGSCGVSYVVQEPGDYEVSIKFNDEHIPDSPFVVPV 2402
            +DG+C V+Y   EPG Y ++IKF D+H+P SP+ V +
Sbjct: 254  EDGTCRVTYKPTEPGTYIINIKFADQHVPGSPYSVKI 364

 Score = 29.6 bits (65), Expect(2) = 4e-22,   Method: Composition-based stats.
 Identities = 12/28 (42%), Positives = 16/28 (57%)
 Frame = +1

Query: 2281 PQEMGPHTVTVKYRGQHVPGSPFQFTVG 2308
            P+E G H V V   G+H+  SPF+   G
Sbjct: 1    PRETGEHLVNVYRNGKHIANSPFKICRG 84

 Score = 76.3 bits (186), Expect(2) = 7e-18,   Method: Compositional matrix adjust.
 Identities = 44/119 (36%), Positives = 67/119 (56%), Gaps = 1/119 (0%)
 Frame = +2

Query: 2500 QSQAGDPGLVSAYGPGLEGGTTGVSSEFIVNTQNAGSGALSVTIDGPSKVQLDCRECPEG 2559
            +S+ G+   V   G GL  G     +EF+V+T+ AG G +S++I+GPSK  ++C +  +G
Sbjct: 83   ESELGNASKVKVSGDGLTEGMANEVNEFVVDTREAGYGGMSLSIEGPSKADIECHDNEDG 262

Query: 2560 HV-VTYTPMAPGNYLIAIKYGGPQHIVGSPFKAKVTGPRLSGGHSLHETSTVLVETVTK 2617
               VTY P  PG Y+I IK+   QH+ GSP+  K+ G          E ST + E +T+
Sbjct: 263  TCRVTYKPTEPGTYIINIKF-ADQHVPGSPYSVKIGG----------EPSTKITERITR 406

 Score = 35.0 bits (79), Expect(2) = 7e-18,   Method: Composition-based stats.
 Identities = 16/31 (51%), Positives = 20/31 (64%)
 Frame = +1

Query: 2471 PHENGVHSIDVKFNGAHIPGSPFKIRVGEQS 2501
            P E G H ++V  NG HI  SPFKI  GE++
Sbjct: 1    PRETGEHLVNVYRNGKHIANSPFKICRGERT 93

 Score = 86.3 bits (212), Expect = 2e-16,   Method: Compositional matrix adjust.
 Identities = 41/89 (46%), Positives = 52/89 (58%)
 Frame = +2

Query: 1062 DPSKVCAYGPGLKGGLVGTPAPFSIDTKXXXXXXXXXXVEGPCEAKIECQDNGDGSCAVS 1121
            + SKV   G GL  G+      F +DT+          +EGP +A IEC DN DG+C V+
Sbjct: 98   NASKVKVSGDGLTEGMANEVNEFVVDTREAGYGGMSLSIEGPSKADIECHDNEDGTCRVT 277

Query: 1122 YLPTEPGEYTINILFAEAHIPGSPFKATI 1150
            Y PTEPG Y INI FA+ H+PGSP+   I
Sbjct: 278  YKPTEPGTYIINIKFADQHVPGSPYSVKI 364

 Score = 73.9 bits (180), Expect(2) = 4e-13,   Method: Compositional matrix adjust.
 Identities = 38/99 (38%), Positives = 53/99 (53%), Gaps = 1/99 (1%)
 Frame = +2

Query: 1337 PKSPFR-VGVTEGCDPTRVRAFGPGLEGGLVNKANRFTVXXXXXXXXXXXXXXXXPSEAK 1395
            P +P R VG +E  + ++V+  G GL  G+ N+ N F V                PS+A 
Sbjct: 56   PTAPSRSVGESELGNASKVKVSGDGLTEGMANEVNEFVVDTREAGYGGMSLSIEGPSKAD 235

Query: 1396 MSCKDNKDGSCTVEYIPFTPGDYDVNITFGGQPIPGSPF 1434
            + C DN+DG+C V Y P  PG Y +NI F  Q +PGSP+
Sbjct: 236  IECHDNEDGTCRVTYKPTEPGTYIINIKFADQHVPGSPY 352

 Score = 21.2 bits (43), Expect(2) = 4e-13,   Method: Composition-based stats.
 Identities = 9/23 (39%), Positives = 13/23 (56%)
 Frame = +1

Query: 1321 EEGVHLVEVLYDEVAVPKSPFRV 1343
            E G HLV V  +   +  SPF++
Sbjct: 7    ETGEHLVNVYRNGKHIANSPFKI 75

 Score = 74.7 bits (182), Expect = 5e-13,   Method: Compositional matrix adjust.
 Identities = 38/100 (38%), Positives = 54/100 (54%)
 Frame = +2

Query: 572 AQKVRAWGPGLETGQVGKSADFVVEAIGTEVGTLGFSIEGPSQAKIECDDKGDGSCDVRY 631
           A KV+  G GL  G   +  +FVV+      G +  SIEGPS+A IEC D  DG+C V Y
Sbjct: 101 ASKVKVSGDGLTEGMANEVNEFVVDTREAGYGGMSLSIEGPSKADIECHDNEDGTCRVTY 280

Query: 632 WPTEPGEYAVHVICDDEDIRDSPFIAHIQPAPPDCFPDKV 671
            PTEPG Y +++   D+ +  SP+   I   P     +++
Sbjct: 281 KPTEPGTYIINIKFADQHVPGSPYSVKIGGEPSTKITERI 400

 Score = 66.2 bits (160), Expect(2) = 2e-12,   Method: Compositional matrix adjust.
 Identities = 36/91 (39%), Positives = 49/91 (53%)
 Frame = +2

Query: 1155 DPSKVRASGPGLERGKAGEAATFTVDCSEAGEAELTIEILSDAGVKAEVLIQNNADGTYH 1214
            + SKV+ SG GL  G A E   F VD  EAG   +++ I  +   KA++   +N DGT  
Sbjct: 98   NASKVKVSGDGLTEGMANEVNEFVVDTREAGYGGMSLSI--EGPSKADIECHDNEDGTCR 271

Query: 1215 ITYSPAFPGTYTITIKYGGHPIPKFPTRVHV 1245
            +TY P  PGTY I IK+    +P  P  V +
Sbjct: 272  VTYKPTEPGTYIINIKFADQHVPGSPYSVKI 364

 Score = 26.6 bits (57), Expect(2) = 2e-12,   Method: Composition-based stats.
 Identities = 11/24 (45%), Positives = 14/24 (58%)
 Frame = +1

Query: 1124 PTEPGEYTINILFAEAHIPGSPFK 1147
            P E GE+ +N+     HI  SPFK
Sbjct: 1    PRETGEHLVNVYRNGKHIANSPFK 72

 Score = 60.8 bits (146), Expect(2) = 3e-09,   Method: Compositional matrix adjust.
 Identities = 33/85 (38%), Positives = 48/85 (56%)
 Frame = +2

Query: 1450 SGPGLGTGVRARVPQTFTVDCSQAGRAPLQVAVLGPTGVAEPVEVRDNGDGTHTVHYTPA 1509
            SG GL  G+   V + F VD  +AG   + +++ GP+     +E  DN DGT  V Y P 
Sbjct: 119  SGDGLTEGMANEVNE-FVVDTREAGYGGMSLSIEGPS--KADIECHDNEDGTCRVTYKPT 289

Query: 1510 TDGPYTVAVKYADQEVPRSPFKIKV 1534
              G Y + +K+ADQ VP SP+ +K+
Sbjct: 290  EPGTYIINIKFADQHVPGSPYSVKI 364

 Score = 21.2 bits (43), Expect(2) = 3e-09,   Method: Composition-based stats.
 Identities = 9/24 (37%), Positives = 14/24 (58%)
 Frame = +1

Query: 1412 PFTPGDYDVNITFGGQPIPGSPFR 1435
            P   G++ VN+   G+ I  SPF+
Sbjct: 1    PRETGEHLVNVYRNGKHIANSPFK 72

 Score = 58.5 bits (140), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 33/91 (36%), Positives = 47/91 (51%)
 Frame = +2

Query: 2635 DASKVVTRGPGLSQAFVGQKNSFTVDCSKAGTNMMMVGVHGPKTPCEEVYVKHMGNRVYN 2694
            +ASKV   G GL++    + N F VD  +AG   M + + GP     E +    G     
Sbjct: 98   NASKVKVSGDGLTEGMANEVNEFVVDTREAGYGGMSLSIEGPSKADIECHDNEDG--TCR 271

Query: 2695 VTYTVKEKGDYILIVKWGDESVPGSPFKVNV 2725
            VTY   E G YI+ +K+ D+ VPGSP+ V +
Sbjct: 272  VTYKPTEPGTYIINIKFADQHVPGSPYSVKI 364

 Score = 58.5 bits (140), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 39/93 (41%), Positives = 53/93 (56%), Gaps = 2/93 (2%)
 Frame = +2

Query: 1539 DASKVRASGPGLNASGIPASLPVEFTIDARDAGQGLLTVQILDPEGKPKKANI--RDNGD 1596
            +ASKV+ SG GL      A+   EF +D R+AG G +++ I   EG P KA+I   DN D
Sbjct: 98   NASKVKVSGDGLTEG--MANEVNEFVVDTREAGYGGMSLSI---EG-PSKADIECHDNED 259

Query: 1597 GTYTVSYLPDMSGRYTITIKYGGDEIPYSPFRI 1629
            GT  V+Y P   G Y I IK+    +P SP+ +
Sbjct: 260  GTCRVTYKPTEPGTYIINIKFADQHVPGSPYSV 358

 Score = 56.2 bits (134), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 33/99 (33%), Positives = 51/99 (51%)
 Frame = +2

Query: 1635 GDASKCLVTVSIGGHGLGACLGPRIQIGEETVITVDAKAAGKGKVTCTVSTPDGAELDVD 1694
            G+ASK    V + G GL   +   +         VD + AG G ++ ++  P  A  D++
Sbjct: 95   GNASK----VKVSGDGLTEGMANEVN-----EFVVDTREAGYGGMSLSIEGPSKA--DIE 241

Query: 1695 VVENHDGTFDIYYTAPEPGKYVITIRFGGEHIPNSPFHV 1733
              +N DGT  + Y   EPG Y+I I+F  +H+P SP+ V
Sbjct: 242  CHDNEDGTCRVTYKPTEPGTYIINIKFADQHVPGSPYSV 358

 Score = 52.0 bits (123), Expect(2) = 5e-07,   Method: Compositional matrix adjust.
 Identities = 33/91 (36%), Positives = 47/91 (51%)
 Frame = +2

Query: 670 KVKAFGPGLEPTGCIVDRPAEFTIDARAAGKGDLKLYAQDADGCPIDIKVIPNGDGTFRC 729
           KVK  G GL  T  + +   EF +D R AG G + L  +       DI+   N DGT R 
Sbjct: 107 KVKVSGDGL--TEGMANEVNEFVVDTREAGYGGMSLSIEGPS--KADIECHDNEDGTCRV 274

Query: 730 SYVPTKPIKHTIIVSWGGVNVPKSPFRVNVG 760
           +Y PT+P  + I + +   +VP SP+ V +G
Sbjct: 275 TYKPTEPGTYIINIKFADQHVPGSPYSVKIG 367

 Score = 22.3 bits (46), Expect(2) = 5e-07,   Method: Composition-based stats.
 Identities = 10/23 (43%), Positives = 15/23 (65%)
 Frame = +1

Query: 633 PTEPGEYAVHVICDDEDIRDSPF 655
           P E GE+ V+V  + + I +SPF
Sbjct: 1   PRETGEHLVNVYRNGKHIANSPF 69

 Score = 51.2 bits (121), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 34/117 (29%), Positives = 58/117 (49%)
 Frame = +2

Query: 453 VAFAGAPITRSPFPVHVAEACNPNACRASGRGLQPKGVRVKEVADFKVFTKGAGSGELKV 512
           +A A    T     V  +E  N +  + SG GL  +G+   EV +F V T+ AG G + +
Sbjct: 35  IAMASTSPTAPSRSVGESELGNASKVKVSGDGLT-EGM-ANEVNEFVVDTREAGYGGMSL 208

Query: 513 TVKGPKGTEEPVKVREAGDGVFECEYYPVVPGKYVVTITWGGYAIPRSPFEVQVSPE 569
           +++GP   +  ++  +  DG     Y P  PG Y++ I +    +P SP+ V++  E
Sbjct: 209 SIEGPSKAD--IECHDNEDGTCRVTYKPTEPGTYIINIKFADQHVPGSPYSVKIGGE 373

 Score = 49.7 bits (117), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 41/114 (35%), Positives = 56/114 (49%), Gaps = 2/114 (1%)
 Frame = +2

Query: 751 PKSPFRVNVGEGS--HPERVKVYGPGVEKTGLKANEPTYFTVDCSEAGQGDVSIGIKCAP 808
           P +P R +VGE    +  +VKV G G+  T   ANE   F VD  EAG G +S+ I+   
Sbjct: 56  PTAPSR-SVGESELGNASKVKVSGDGL--TEGMANEVNEFVVDTREAGYGGMSLSIE--- 217

Query: 809 GVVGPVEAXXXXXXXXXXXXTFTVKYTPPGAGHYTIMVLFANQEIPASPFHIKV 862
              GP +A              T K T PG   Y I + FA+Q +P SP+ +K+
Sbjct: 218 ---GPSKADIECHDNEDGTCRVTYKPTEPGT--YIINIKFADQHVPGSPYSVKI 364

 Score = 46.6 bits (109), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 34/96 (35%), Positives = 49/96 (51%)
 Frame = +2

Query: 1250 DTSGIKVSGPGVEPHGVLREVTTEFTVDARSLTATGGNHVTARVLNPSGAKTDTYVTDNG 1309
            + S +KVSG G+   G+  EV  EF VD R     G   ++  +  PS  K D    DN 
Sbjct: 98   NASKVKVSGDGL-TEGMANEVN-EFVVDTRE---AGYGGMSLSIEGPS--KADIECHDNE 256

Query: 1310 DGTYRVQYTAYEEGVHLVEVLYDEVAVPKSPFRVGV 1345
            DGT RV Y   E G +++ + + +  VP SP+ V +
Sbjct: 257  DGTCRVTYKPTEPGTYIINIKFADQHVPGSPYSVKI 364

 Score = 46.2 bits (108), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 30/97 (30%), Positives = 48/97 (49%)
 Frame = +2

Query: 373 LGDANKVSARGPGLEPVGNVANKPTYFDIYTAGAGTGDVAVVIVDPQGRRDTVEVALEDK 432
           LG+A+KV   G GL     +AN+   F + T  AG G +++ I  P       ++   D 
Sbjct: 92  LGNASKVKVSGDGLTE--GMANEVNEFVVDTREAGYGGMSLSIEGPS----KADIECHDN 253

Query: 433 GDNTFRCTYRPVMEGPHTVHVAFAGAPITRSPFPVHV 469
            D T R TY+P   G + +++ FA   +  SP+ V +
Sbjct: 254 EDGTCRVTYKPTEPGTYIINIKFADQHVPGSPYSVKI 364

 Score = 44.7 bits (104), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 32/92 (34%), Positives = 45/92 (48%), Gaps = 1/92 (1%)
 Frame = +2

Query: 966  DLSKVKVQGLNSKVAVGQE-QAFSVNTRGAGGQGQLDVRMTSPSRRPIPCKLEPGGGAEA 1024
            + SKVKV G      +  E   F V+TR AG  G + + +  PS+  I C     G    
Sbjct: 98   NASKVKVSGDGLTEGMANEVNEFVVDTREAG-YGGMSLSIEGPSKADIECHDNEDGTCR- 271

Query: 1025 QAVRYMPPEEGPYKVDITYDGHPVPGSPFAVE 1056
              V Y P E G Y ++I +    VPGSP++V+
Sbjct: 272  --VTYKPTEPGTYIINIKFADQHVPGSPYSVK 361

 Score = 40.4 bits (93), Expect(2) = 6e-04,   Method: Compositional matrix adjust.
 Identities = 28/94 (29%), Positives = 47/94 (50%), Gaps = 3/94 (3%)
 Frame = +2

Query: 2408 DARRLTVTSLQETGLKVNQPASFAVQLNGA-RGVIDARVHTPSGAVEECYVSELDSDKHT 2466
            +A ++ V+    T    N+   F V    A  G +   +  PS A  EC+    D++  T
Sbjct: 98   NASKVKVSGDGLTEGMANEVNEFVVDTREAGYGGMSLSIEGPSKADIECH----DNEDGT 265

Query: 2467 IR--FIPHENGVHSIDVKFNGAHIPGSPFKIRVG 2498
             R  + P E G + I++KF   H+PGSP+ +++G
Sbjct: 266  CRVTYKPTEPGTYIINIKFADQHVPGSPYSVKIG 367

 Score = 23.5 bits (49), Expect(2) = 6e-04,   Method: Composition-based stats.
 Identities = 9/24 (37%), Positives = 17/24 (70%)
 Frame = +1

Query: 2377 QEPGDYEVSIKFNDEHIPDSPFVV 2400
            +E G++ V++  N +HI +SPF +
Sbjct: 4    RETGEHLVNVYRNGKHIANSPFKI 75

 Score = 42.0 bits (97), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 18/39 (46%), Positives = 24/39 (61%)
 Frame = +2

Query: 1817 DNKDGTITVRYAPTEKGLHQMGIKYDGNHIPGSPLQFYV 1855
            DN+DGT  V Y PTE G + + IK+   H+PGSP    +
Sbjct: 248  DNEDGTCRVTYKPTEPGTYIINIKFADQHVPGSPYSVKI 364

 Score = 39.3 bits (90), Expect = 0.024,   Method: Compositional matrix adjust.
 Identities = 21/64 (32%), Positives = 31/64 (48%)
 Frame = +2

Query: 2245 EASSQDMTAQVTSPSGKTEAAEIVEGEDSAYSVRFVPQEMGPHTVTVKYRGQHVPGSPFQ 2304
            EA    M+  +  PS      E  + ED    V + P E G + + +K+  QHVPGSP+ 
Sbjct: 182  EAGYGGMSLSIEGPS--KADIECHDNEDGTCRVTYKPTEPGTYIINIKFADQHVPGSPYS 355

Query: 2305 FTVG 2308
              +G
Sbjct: 356  VKIG 367
>21436
          Length = 546

 Score =  147 bits (372), Expect = 5e-35,   Method: Compositional matrix adjust.
 Identities = 80/172 (46%), Positives = 110/172 (63%)
 Frame = -1

Query: 722 NGDGTFRCSYVPTKPIKHTIIVSWGGVNVPKSPFRVNVGEGSHPERVKVYGPGVEKTGLK 781
           N DGT+ C Y+P +P+KHT+ V++GGV VP SPFRV+V E S P +VK+ GPGV   G+K
Sbjct: 546 NRDGTYACRYMPLRPVKHTVSVNFGGVAVPNSPFRVHVAEPSDPSKVKISGPGVTN-GIK 370

Query: 782 ANEPTYFTVDCSEAGQGDVSIGIKCAPGVVGPVEAXXXXXXXXXXXXTFTVKYTPPGAGH 841
              PTYFTVDC +AG GDV++G+    G+  PV+             TFTV+Y P   G 
Sbjct: 369 TMSPTYFTVDCKQAGPGDVAVGLTDGRGMDVPVKT------TGNQDGTFTVEYEPKLPGT 208

Query: 842 YTIMVLFANQEIPASPFHIKVDPSHDASKVKAEGPGLSRTGVEVGKPTHFTV 893
           YT+MV FA+ E+P+SP  +KV+P+ D S ++ +G   SR  +E   P+ F V
Sbjct: 207 YTVMVYFADVEVPSSPVKVKVEPNIDVSSIRVDGLD-SRVFIE--APSEFVV 61

 Score =  120 bits (302), Expect = 5e-27,   Method: Compositional matrix adjust.
 Identities = 72/185 (38%), Positives = 96/185 (51%)
 Frame = -1

Query: 1401 NKDGSCTVEYIPFTPGDYDVNITFGGQPIPGSPFRXXXXXXXXXXXXXCSGPGLGTGVRA 1460
            N+DG+    Y+P  P  + V++ FGG  +P SPFR              SGPG+  G++ 
Sbjct: 546  NRDGTYACRYMPLRPVKHTVSVNFGGVAVPNSPFRVHVAEPSDPSKVKISGPGVTNGIKT 367

Query: 1461 RVPQTFTVDCSQAGRAPLQVAVLGPTGVAEPVEVRDNGDGTHTVHYTPATDGPYTVAVKY 1520
              P  FTVDC QAG   + V +    G+  PV+   N DGT TV Y P   G YTV V +
Sbjct: 366  MSPTYFTVDCKQAGPGDVAVGLTDGRGMDVPVKTTGNQDGTFTVEYEPKLPGTYTVMVYF 187

Query: 1521 ADQEVPRSPFKIKVLPSHDASKVRASGPGLNASGIPASLPVEFTIDARDAGQGLLTVQIL 1580
            AD EVP SP K+KV P+ D S +R    GL+ S +    P EF +DA           +L
Sbjct: 186  ADVEVPSSPVKVKVEPNIDVSSIRVD--GLD-SRVFIEAPSEFVVDA----------SVL 46

Query: 1581 DPEGK 1585
            DP+G+
Sbjct: 45   DPKGQ 31

 Score =  120 bits (300), Expect = 9e-27,   Method: Compositional matrix adjust.
 Identities = 66/185 (35%), Positives = 96/185 (51%), Gaps = 1/185 (0%)
 Frame = -1

Query: 1113 NGDGSCAVSYLPTEPGEYTINILFAEAHIPGSPFKATIQPVFDPSKVRASGPGLERG-KA 1171
            N DG+ A  Y+P  P ++T+++ F    +P SPF+  +    DPSKV+ SGPG+  G K 
Sbjct: 546  NRDGTYACRYMPLRPVKHTVSVNFGGVAVPNSPFRVHVAEPSDPSKVKISGPGVTNGIKT 367

Query: 1172 GEAATFTVDCSEAGEAELTIEILSDAGVKAEVLIQNNADGTYHITYSPAFPGTYTITIKY 1231
                 FTVDC +AG  ++ + +    G+   V    N DGT+ + Y P  PGTYT+ + +
Sbjct: 366  MSPTYFTVDCKQAGPGDVAVGLTDGRGMDVPVKTTGNQDGTFTVEYEPKLPGTYTVMVYF 187

Query: 1232 GGHPIPKFPTRVHVQPAVDTSGIKVSGPGVEPHGVLREVTTEFTVDARSLTATGGNHVTA 1291
                +P  P +V V+P +D S I+V G       V  E  +EF VDA  L   G   V A
Sbjct: 186  ADVEVPSSPVKVKVEPNIDVSSIRVDGLDSR---VFIEAPSEFVVDASVLDPKGQGEVEA 16

Query: 1292 RVLNP 1296
             +  P
Sbjct: 15   ILTTP 1

 Score = 99.8 bits (247), Expect = 2e-20,   Method: Compositional matrix adjust.
 Identities = 67/193 (34%), Positives = 95/193 (49%), Gaps = 3/193 (1%)
 Frame = -1

Query: 1497 NGDGTHTVHYTPATDGPYTVAVKYADQEVPRSPFKIKVLPSHDASKVRASGPGLNASGIP 1556
            N DGT+   Y P     +TV+V +    VP SPF++ V    D SKV+ SGPG+  +GI 
Sbjct: 546  NRDGTYACRYMPLRPVKHTVSVNFGGVAVPNSPFRVHVAEPSDPSKVKISGPGVT-NGIK 370

Query: 1557 ASLPVEFTIDARDAGQGLLTVQILDPEGKPKKANIRDNGDGTYTVSYLPDMSGRYTITIK 1616
               P  FT+D + AG G + V + D  G         N DGT+TV Y P + G YT+ + 
Sbjct: 369  TMSPTYFTVDCKQAGPGDVAVGLTDGRGMDVPVKTTGNQDGTFTVEYEPKLPGTYTVMVY 190

Query: 1617 YGGDEIPYSPFRIHALPTGDASKCLVTVSIGGHGLGACLGPRIQIGEETVITVDAKA--- 1673
            +   E+P SP ++   P  D S      SI   GL +    R+ I   +   VDA     
Sbjct: 189  FADVEVPSSPVKVKVEPNIDVS------SIRVDGLDS----RVFIEAPSEFVVDASVLDP 40

Query: 1674 AGKGKVTCTVSTP 1686
             G+G+V   ++TP
Sbjct: 39   KGQGEVEAILTTP 1

 Score = 95.5 bits (236), Expect = 2e-19,   Method: Compositional matrix adjust.
 Identities = 53/146 (36%), Positives = 74/146 (50%)
 Frame = -1

Query: 434 DNTFRCTYRPVMEGPHTVHVAFAGAPITRSPFPVHVAEACNPNACRASGRGLQPKGVRVK 493
           D T+ C Y P+    HTV V F G  +  SPF VHVAE  +P+  + SG G+   G++  
Sbjct: 540 DGTYACRYMPLRPVKHTVSVNFGGVAVPNSPFRVHVAEPSDPSKVKISGPGVT-NGIKTM 364

Query: 494 EVADFKVFTKGAGSGELKVTVKGPKGTEEPVKVREAGDGVFECEYYPVVPGKYVVTITWG 553
               F V  K AG G++ V +   +G + PVK     DG F  EY P +PG Y V + + 
Sbjct: 363 SPTYFTVDCKQAGPGDVAVGLTDGRGMDVPVKTTGNQDGTFTVEYEPKLPGTYTVMVYFA 184

Query: 554 GYAIPRSPFEVQVSPEAGAQKVRAWG 579
              +P SP +V+V P      +R  G
Sbjct: 183 DVEVPSSPVKVKVEPNIDVSSIRVDG 106

 Score = 87.4 bits (215), Expect = 7e-17,   Method: Compositional matrix adjust.
 Identities = 60/182 (32%), Positives = 91/182 (50%), Gaps = 3/182 (1%)
 Frame = -1

Query: 829  TFTVKYTPPGAGHYTIMVLFANQEIPASPFHIKVDPSHDASKVKAEGPGLSRTGVEVGKP 888
            T+  +Y P     +T+ V F    +P SPF + V    D SKVK  GPG++  G++   P
Sbjct: 534  TYACRYMPLRPVKHTVSVNFGGVAVPNSPFRVHVAEPSDPSKVKISGPGVTN-GIKTMSP 358

Query: 889  THFTVLTKGAGKAKLDVHFAGAAKGEAVR-DFEIIDNHDYSYTVKYTAVQQGNMAVTVTY 947
            T+FTV  K AG   + V   G   G  +    +   N D ++TV+Y     G   V V +
Sbjct: 357  TYFTVDCKQAGPGDVAV---GLTDGRGMDVPVKTTGNQDGTFTVEYEPKLPGTYTVMVYF 187

Query: 948  GGDPVPKSPFVVNVAPPLDLSKVKVQGLNSKVAVGQEQAFSVNTR--GAGGQGQLDVRMT 1005
                VP SP  V V P +D+S ++V GL+S+V +     F V+       GQG+++  +T
Sbjct: 186  ADVEVPSSPVKVKVEPNIDVSSIRVDGLDSRVFIEAPSEFVVDASVLDPKGQGEVEAILT 7

Query: 1006 SP 1007
            +P
Sbjct: 6    TP 1

 Score = 84.3 bits (207), Expect = 6e-16,   Method: Compositional matrix adjust.
 Identities = 54/151 (35%), Positives = 75/151 (49%)
 Frame = -1

Query: 1208 NADGTYHITYSPAFPGTYTITIKYGGHPIPKFPTRVHVQPAVDTSGIKVSGPGVEPHGVL 1267
            N DGTY   Y P  P  +T+++ +GG  +P  P RVHV    D S +K+SGPGV  +G+ 
Sbjct: 546  NRDGTYACRYMPLRPVKHTVSVNFGGVAVPNSPFRVHVAEPSDPSKVKISGPGVT-NGIK 370

Query: 1268 REVTTEFTVDARSLTATGGNHVTARVLNPSGAKTDTYVTDNGDGTYRVQYTAYEEGVHLV 1327
                T FTVD +     G   V   + +  G       T N DGT+ V+Y     G + V
Sbjct: 369  TMSPTYFTVDCKQ---AGPGDVAVGLTDGRGMDVPVKTTGNQDGTFTVEYEPKLPGTYTV 199

Query: 1328 EVLYDEVAVPKSPFRVGVTEGCDPTRVRAFG 1358
             V + +V VP SP +V V    D + +R  G
Sbjct: 198  MVYFADVEVPSSPVKVKVEPNIDVSSIRVDG 106

 Score = 82.4 bits (202), Expect = 2e-15,   Method: Compositional matrix adjust.
 Identities = 49/140 (35%), Positives = 69/140 (49%)
 Frame = -1

Query: 1594 NGDGTYTVSYLPDMSGRYTITIKYGGDEIPYSPFRIHALPTGDASKCLVTVSIGGHGLGA 1653
            N DGTY   Y+P    ++T+++ +GG  +P SPFR+H     D SK    V I G G+  
Sbjct: 546  NRDGTYACRYMPLRPVKHTVSVNFGGVAVPNSPFRVHVAEPSDPSK----VKISGPGVTN 379

Query: 1654 CLGPRIQIGEETVITVDAKAAGKGKVTCTVSTPDGAELDVDVVENHDGTFDIYYTAPEPG 1713
                 I+    T  TVD K AG G V   ++   G ++ V    N DGTF + Y    PG
Sbjct: 378  G----IKTMSPTYFTVDCKQAGPGDVAVGLTDGRGMDVPVKTTGNQDGTFTVEYEPKLPG 211

Query: 1714 KYVITIRFGGEHIPNSPFHV 1733
             Y + + F    +P+SP  V
Sbjct: 210  TYTVMVYFADVEVPSSPVKV 151

 Score = 81.6 bits (200), Expect = 4e-15,   Method: Compositional matrix adjust.
 Identities = 61/180 (33%), Positives = 85/180 (47%), Gaps = 3/180 (1%)
 Frame = -1

Query: 624 DGSCDVRYWPTEPGEYAVHVICDDEDIRDSPFIAHIQPAPPDCFPDKVKAFGPGLEPTGC 683
           DG+   RY P  P ++ V V      + +SPF  H+   P D  P KVK  GPG+   G 
Sbjct: 540 DGTYACRYMPLRPVKHTVSVNFGGVAVPNSPFRVHVA-EPSD--PSKVKISGPGVT-NGI 373

Query: 684 IVDRPAEFTIDARAAGKGDLKLYAQDADGCPIDIKVIPNGDGTFRCSYVPTKPIKHTIIV 743
               P  FT+D + AG GD+ +   D  G  + +K   N DGTF   Y P  P  +T++V
Sbjct: 372 KTMSPTYFTVDCKQAGPGDVAVGLTDGRGMDVPVKTTGNQDGTFTVEYEPKLPGTYTVMV 193

Query: 744 SWGGVNVPKSPFRVNVGEGSHPERVKVYGPGVEKTGLKANEPTYFTVDCS---EAGQGDV 800
            +  V VP SP +V V        ++V G     + +    P+ F VD S     GQG+V
Sbjct: 192 YFADVEVPSSPVKVKVEPNIDVSSIRVDG---LDSRVFIEAPSEFVVDASVLDPKGQGEV 22

 Score = 80.1 bits (196), Expect = 1e-14,   Method: Compositional matrix adjust.
 Identities = 55/161 (34%), Positives = 77/161 (47%), Gaps = 4/161 (2%)
 Frame = -1

Query: 1026 AVRYMPPEEGPYKVDITYDGHPVPGSPFAVEGVLPPDPSKVCAYGPGLKGGL-VGTPAPF 1084
            A RYMP     + V + + G  VP SPF V    P DPSKV   GPG+  G+   +P  F
Sbjct: 528  ACRYMPLRPVKHTVSVNFGGVAVPNSPFRVHVAEPSDPSKVKISGPGVTNGIKTMSPTYF 349

Query: 1085 SIDTKXXXXXXXXXXVEGP--CEAKIECQDNGDGSCAVSYLPTEPGEYTINILFAEAHIP 1142
            ++D K          +      +  ++   N DG+  V Y P  PG YT+ + FA+  +P
Sbjct: 348  TVDCKQAGPGDVAVGLTDGRGMDVPVKTTGNQDGTFTVEYEPKLPGTYTVMVYFADVEVP 169

Query: 1143 GSPFKATIQPVFDPSKVRASGPGLERGKAGEA-ATFTVDCS 1182
             SP K  ++P  D S +R    GL+     EA + F VD S
Sbjct: 168  SSPVKVKVEPNIDVSSIRVD--GLDSRVFIEAPSEFVVDAS 52

 Score = 77.8 bits (190), Expect = 6e-14,   Method: Compositional matrix adjust.
 Identities = 44/134 (32%), Positives = 70/134 (52%), Gaps = 4/134 (2%)
 Frame = -1

Query: 1818 NKDGTITVRYAPTEKGLHQMGIKYDGNHIPGSPLQFYV-DAINSRHVSAYGPGLSHGM-V 1875
            N+DGT   RY P     H + + + G  +P SP + +V +  +   V   GPG+++G+  
Sbjct: 546  NRDGTYACRYMPLRPVKHTVSVNFGGVAVPNSPFRVHVAEPSDPSKVKISGPGVTNGIKT 367

Query: 1876 NKPATFTIVTKDAGEGGLSLAVEGPSKAEITCKD--NKDGTCTVSYLPTAPGDYSIIVRF 1933
              P  FT+  K AG G +++ +      ++  K   N+DGT TV Y P  PG Y+++V F
Sbjct: 366  MSPTYFTVDCKQAGPGDVAVGLTDGRGMDVPVKTTGNQDGTFTVEYEPKLPGTYTVMVYF 187

Query: 1934 DDKHIPGSPFTAKI 1947
             D  +P SP   K+
Sbjct: 186  ADVEVPSSPVKVKV 145

 Score = 77.0 bits (188), Expect = 9e-14,   Method: Compositional matrix adjust.
 Identities = 64/191 (33%), Positives = 84/191 (43%)
 Frame = -1

Query: 332 DKDRTYAVSYVPKVAGLHKVTVLFAGQNIERSPFEVNVGMALGDANKVSARGPGLEPVGN 391
           ++D TYA  Y+P     H V+V F G  +  SPF V+V     D +KV   GPG+   G 
Sbjct: 546 NRDGTYACRYMPLRPVKHTVSVNFGGVAVPNSPFRVHVAEP-SDPSKVKISGPGVTN-GI 373

Query: 392 VANKPTYFDIYTAGAGTGDVAVVIVDPQGRRDTVEVALEDKGDNTFRCTYRPVMEGPHTV 451
               PTYF +    AG GDVAV + D  GR   V V      D TF   Y P + G +TV
Sbjct: 372 KTMSPTYFTVDCKQAGPGDVAVGLTD--GRGMDVPVKTTGNQDGTFTVEYEPKLPGTYTV 199

Query: 452 HVAFAGAPITRSPFPVHVAEACNPNACRASGRGLQPKGVRVKEVADFKVFTKGAGSGELK 511
            V FA   +  SP  V V    + ++ R  G              D +VF +      + 
Sbjct: 198 MVYFADVEVPSSPVKVKVEPNIDVSSIRVDG-------------LDSRVFIEAPSEFVVD 58

Query: 512 VTVKGPKGTEE 522
            +V  PKG  E
Sbjct: 57  ASVLDPKGQGE 25

 Score = 73.6 bits (179), Expect = 1e-12,   Method: Compositional matrix adjust.
 Identities = 48/127 (37%), Positives = 68/127 (53%), Gaps = 3/127 (2%)
 Frame = -1

Query: 2006 FTPKEVGEHVVSVRKSGKHVTNSPFKILVGPSEIGDASKVRVWGKGLSEG-QTFQVAEFI 2064
            + P    +H VSV   G  V NSPF++ V  +E  D SKV++ G G++ G +T     F 
Sbjct: 519  YMPLRPVKHTVSVNFGGVAVPNSPFRVHV--AEPSDPSKVKISGPGVTNGIKTMSPTYFT 346

Query: 2065 VDTRNAGYGGLGLSIEGPSKVDINCEDM--EDGTCKVTYCPTEPGTYIINIKFADKHVPG 2122
            VD + AG G + + +     +D+  +    +DGT  V Y P  PGTY + + FAD  VP 
Sbjct: 345  VDCKQAGPGDVAVGLTDGRGMDVPVKTTGNQDGTFTVEYEPKLPGTYTVMVYFADVEVPS 166

Query: 2123 SPFTVKV 2129
            SP  VKV
Sbjct: 165  SPVKVKV 145

 Score = 72.0 bits (175), Expect = 3e-12,   Method: Compositional matrix adjust.
 Identities = 55/167 (32%), Positives = 70/167 (41%), Gaps = 3/167 (1%)
 Frame = -1

Query: 1308 NGDGTYRVQYTAYEEGVHLVEVLYDEVAVPKSPFRVGVTEGCDPTRVRAFGPGLEGGLVN 1367
            N DGTY  +Y       H V V +  VAVP SPFRV V E  DP++V+  GPG+  G+  
Sbjct: 546  NRDGTYACRYMPLRPVKHTVSVNFGGVAVPNSPFRVHVAEPSDPSKVKISGPGVTNGIKT 367

Query: 1368 KA-NRFTVXXXXXXXXXXXXXXXXPSEAKMSCKD--NKDGSCTVEYIPFTPGDYDVNITF 1424
             +   FTV                     +  K   N+DG+ TVEY P  PG Y V + F
Sbjct: 366  MSPTYFTVDCKQAGPGDVAVGLTDGRGMDVPVKTTGNQDGTFTVEYEPKLPGTYTVMVYF 187

Query: 1425 GGQPIPGSPFRXXXXXXXXXXXXXCSGPGLGTGVRARVPQTFTVDCS 1471
                +P SP +                 GL + V    P  F VD S
Sbjct: 186  ADVEVPSSPVKVKVEPNIDVSSIRVD--GLDSRVFIEAPSEFVVDAS 52

 Score = 64.7 bits (156), Expect = 5e-10,   Method: Compositional matrix adjust.
 Identities = 53/190 (27%), Positives = 87/190 (45%), Gaps = 7/190 (3%)
 Frame = -1

Query: 2271 EDSAYSVRFVPQEMGPHTVTVKYRGQHVPGSPFQFTVGPLGEGGAHKVRAGGTGLERGVA 2330
             D  Y+ R++P     HTV+V + G  VP SPF+  V    +    KV+  G G+  G+ 
Sbjct: 543  RDGTYACRYMPLRPVKHTVSVNFGGVAVPNSPFRVHVAEPSD--PSKVKISGPGVTNGIK 370

Query: 2331 GV-PAEFSIWTREAGAGGLSIAVEGPSKAEIAFED--RKDGSCGVSYVVQEPGDYEVSIK 2387
             + P  F++  ++AG G +++ +      ++  +    +DG+  V Y  + PG Y V + 
Sbjct: 369  TMSPTYFTVDCKQAGPGDVAVGLTDGRGMDVPVKTTGNQDGTFTVEYEPKLPGTYTVMVY 190

Query: 2388 FNDEHIPDSPFVVPVASLSDDARRLTVTSLQETGLK----VNQPASFAVQLNGARGVIDA 2443
            F D  +P SP  V V         + V+S++  GL     +  P+ F         V+DA
Sbjct: 189  FADVEVPSSPVKVKVEP------NIDVSSIRVDGLDSRVFIEAPSEF---------VVDA 55

Query: 2444 RVHTPSGAVE 2453
             V  P G  E
Sbjct: 54   SVLDPKGQGE 25

 Score = 55.5 bits (132), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 44/135 (32%), Positives = 64/135 (47%), Gaps = 2/135 (1%)
 Frame = -1

Query: 924  NHDYSYTVKYTAVQQGNMAVTVTYGGDPVPKSPFVVNVAPPLDLSKVKVQ--GLNSKVAV 981
            N D +Y  +Y  ++     V+V +GG  VP SPF V+VA P D SKVK+   G+ + +  
Sbjct: 546  NRDGTYACRYMPLRPVKHTVSVNFGGVAVPNSPFRVHVAEPSDPSKVKISGPGVTNGIKT 367

Query: 982  GQEQAFSVNTRGAGGQGQLDVRMTSPSRRPIPCKLEPGGGAEAQAVRYMPPEEGPYKVDI 1041
                 F+V+ + A G G + V +T      +P K   G       V Y P   G Y V +
Sbjct: 366  MSPTYFTVDCKQA-GPGDVAVGLTDGRGMDVPVKTT-GNQDGTFTVEYEPKLPGTYTVMV 193

Query: 1042 TYDGHPVPGSPFAVE 1056
             +    VP SP  V+
Sbjct: 192  YFADVEVPSSPVKVK 148

 Score = 49.7 bits (117), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 46/165 (27%), Positives = 67/165 (40%), Gaps = 3/165 (1%)
 Frame = -1

Query: 2564 YTPMAPGNYLIAIKYGGPQHIVGSPFKAKVTGPRLSGGHSLHETSTVLVETVTKXXXXXX 2623
            Y P+ P  + +++ +GG   +  SPF+  V  P                           
Sbjct: 519  YMPLRPVKHTVSVNFGG-VAVPNSPFRVHVAEP--------------------------- 424

Query: 2624 XXXXXIPKFSSDASKVVTRGPGLSQAFVGQKNS-FTVDCSKAGTNMMMVGVHGPKTPCEE 2682
                      SD SKV   GPG++        + FTVDC +AG   + VG+   +    +
Sbjct: 423  ----------SDPSKVKISGPGVTNGIKTMSPTYFTVDCKQAGPGDVAVGLTDGR--GMD 280

Query: 2683 VYVKHMGNR--VYNVTYTVKEKGDYILIVKWGDESVPGSPFKVNV 2725
            V VK  GN+   + V Y  K  G Y ++V + D  VP SP KV V
Sbjct: 279  VPVKTTGNQDGTFTVEYEPKLPGTYTVMVYFADVEVPSSPVKVKV 145

 Score = 48.9 bits (115), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 41/162 (25%), Positives = 70/162 (43%), Gaps = 3/162 (1%)
 Frame = -1

Query: 1698 NHDGTFDIYYTAPEPGKYVITIRFGGEHIPNSPFHVLACDPLPHVEEPAEMLQMRQPYAP 1757
            N DGT+   Y    P K+ +++ FGG  +PNSPF V       HV EP++  +++     
Sbjct: 546  NRDGTYACRYMPLRPVKHTVSVNFGGVAVPNSPFRV-------HVAEPSDPSKVKISGPG 388

Query: 1758 LRPG---TCPTHWATXXXXXXXXXLESMLRPFNLVIPFTVQKGELTGEVRMPSGKTARPN 1814
            +  G     PT++                 P ++ +  T  +G     + +P   T    
Sbjct: 387  VTNGIKTMSPTYFTVDCKQAG---------PGDVAVGLTDGRG-----MDVPVKTTG--- 259

Query: 1815 ITDNKDGTITVRYAPTEKGLHQMGIKYDGNHIPGSPLQFYVD 1856
               N+DGT TV Y P   G + + + +    +P SP++  V+
Sbjct: 258  ---NQDGTFTVEYEPKLPGTYTVMVYFADVEVPSSPVKVKVE 142

 Score = 45.1 bits (105), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 37/135 (27%), Positives = 57/135 (42%), Gaps = 2/135 (1%)
 Frame = -1

Query: 2365 RKDGSCGVSYVVQEPGDYEVSIKFNDEHIPDSPFVVPVASLSDDARRLTVTSLQETGLKV 2424
             +DG+    Y+   P  + VS+ F    +P+SPF V VA  SD ++          G+K 
Sbjct: 546  NRDGTYACRYMPLRPVKHTVSVNFGGVAVPNSPFRVHVAEPSDPSKVKISGPGVTNGIKT 367

Query: 2425 NQPASFAVQLNGARGVIDARVHTPSGAVEECYVSELDSDK--HTIRFIPHENGVHSIDVK 2482
              P  F V    A G  D  V    G   +  V    +     T+ + P   G +++ V 
Sbjct: 366  MSPTYFTVDCKQA-GPGDVAVGLTDGRGMDVPVKTTGNQDGTFTVEYEPKLPGTYTVMVY 190

Query: 2483 FNGAHIPGSPFKIRV 2497
            F    +P SP K++V
Sbjct: 189  FADVEVPSSPVKVKV 145
>27230
          Length = 583

 Score = 74.7 bits (182), Expect(2) = 1e-25,   Method: Compositional matrix adjust.
 Identities = 40/81 (49%), Positives = 48/81 (59%)
 Frame = -1

Query: 1285 GGNHVTARVLNPSGAKTDTYVTDNGDGTYRVQYTAYEEGVHLVEVLYDEVAVPKSPFRVG 1344
            G   V A +  PSG K  T V +  DGTY V YT  EEG   ++V Y  + +P SPF+V 
Sbjct: 247  GQGEVEAILTTPSGRKLQTLVDNMKDGTYPVLYTPMEEGPQSLDVTYKGIPIPGSPFQVN 68

Query: 1345 VTEGCDPTRVRAFGPGLEGGL 1365
               G D  RVRA+GPGLEGGL
Sbjct: 67   AVAGYDANRVRAYGPGLEGGL 5

 Score = 62.8 bits (151), Expect(2) = 1e-25,   Method: Compositional matrix adjust.
 Identities = 33/85 (38%), Positives = 46/85 (54%), Gaps = 3/85 (3%)
 Frame = -2

Query: 1200 KAEVLIQNNADGTYHITYSPAFPGTYTITIKYGGHPIPKFPTRVHVQPAV---DTSGIKV 1256
            K+++   N  DGT ++TY P FPG Y + + +G  P+P  P    + P+    D S I  
Sbjct: 513  KSKINCVNXDDGTVNVTYIPEFPGEYKVKVSHGDKPVPGSPFTALITPSELDPDVSSITA 334

Query: 1257 SGPGVEPHGVLREVTTEFTVDARSL 1281
            SG G+ P GV  E  +EF VDA  L
Sbjct: 333  SGYGISPEGVFIEAPSEFVVDASVL 259

 Score = 61.6 bits (148), Expect(2) = 2e-17,   Method: Compositional matrix adjust.
 Identities = 33/85 (38%), Positives = 47/85 (55%)
 Frame = -2

Query: 612 PSQAKIECDDKGDGSCDVRYWPTEPGEYAVHVICDDEDIRDSPFIAHIQPAPPDCFPDKV 671
           P ++KI C +  DG+ +V Y P  PGEY V V   D+ +  SPF A I P+  D     +
Sbjct: 519 PEKSKINCVNXDDGTVNVTYIPEFPGEYKVKVSHGDKPVPGSPFTALITPSELDPDVSSI 340

Query: 672 KAFGPGLEPTGCIVDRPAEFTIDAR 696
            A G G+ P G  ++ P+EF +DA 
Sbjct: 339 TASGYGISPEGVFIEAPSEFVVDAS 265

 Score = 47.8 bits (112), Expect(2) = 2e-17,   Method: Compositional matrix adjust.
 Identities = 25/78 (32%), Positives = 41/78 (52%)
 Frame = -1

Query: 699 GKGDLKLYAQDADGCPIDIKVIPNGDGTFRCSYVPTKPIKHTIIVSWGGVNVPKSPFRVN 758
           G+G+++       G  +   V    DGT+   Y P +    ++ V++ G+ +P SPF+VN
Sbjct: 247 GQGEVEAILTTPSGRKLQTLVDNMKDGTYPVLYTPMEEGPQSLDVTYKGIPIPGSPFQVN 68

Query: 759 VGEGSHPERVKVYGPGVE 776
              G    RV+ YGPG+E
Sbjct: 67  AVAGYDANRVRAYGPGLE 14

 Score = 55.8 bits (133), Expect(2) = 7e-17,   Method: Compositional matrix adjust.
 Identities = 28/77 (36%), Positives = 45/77 (58%)
 Frame = -1

Query: 1474 GRAPLQVAVLGPTGVAEPVEVRDNGDGTHTVHYTPATDGPYTVAVKYADQEVPRSPFKIK 1533
            G+  ++  +  P+G      V +  DGT+ V YTP  +GP ++ V Y    +P SPF++ 
Sbjct: 247  GQGEVEAILTTPSGRKLQTLVDNMKDGTYPVLYTPMEEGPQSLDVTYKGIPIPGSPFQVN 68

Query: 1534 VLPSHDASKVRASGPGL 1550
             +  +DA++VRA GPGL
Sbjct: 67   AVAGYDANRVRAYGPGL 17

 Score = 52.0 bits (123), Expect(2) = 7e-17,   Method: Compositional matrix adjust.
 Identities = 30/85 (35%), Positives = 42/85 (49%), Gaps = 4/85 (4%)
 Frame = -2

Query: 1391 PSEAKMSCKDNKDGSCTVEYIPFTPGDYDVNITFGGQPIPGSPFRXXXXXXXX---XXXX 1447
            P ++K++C +  DG+  V YIP  PG+Y V ++ G +P+PGSPF                
Sbjct: 519  PEKSKINCVNXDDGTVNVTYIPEFPGEYKVKVSHGDKPVPGSPFTALITPSELDPDVSSI 340

Query: 1448 XCSGPGLG-TGVRARVPQTFTVDCS 1471
              SG G+   GV    P  F VD S
Sbjct: 339  TASGYGISPEGVFIEAPSEFVVDAS 265

 Score = 53.1 bits (126), Expect(2) = 7e-16,   Method: Compositional matrix adjust.
 Identities = 35/85 (41%), Positives = 48/85 (56%), Gaps = 5/85 (5%)
 Frame = -2

Query: 1103 PCEAKIECQDNGDGSCAVSYLPTEPGEYTINILFAEAHIPGSPFKATIQPV-FDP--SKV 1159
            P ++KI C +  DG+  V+Y+P  PGEY + +   +  +PGSPF A I P   DP  S +
Sbjct: 519  PEKSKINCVNXDDGTVNVTYIPEFPGEYKVKVSHGDKPVPGSPFTALITPSELDPDVSSI 340

Query: 1160 RASGPGLE-RGKAGEAAT-FTVDCS 1182
             ASG G+   G   EA + F VD S
Sbjct: 339  TASGYGISPEGVFIEAPSEFVVDAS 265

 Score = 51.2 bits (121), Expect(2) = 7e-16,   Method: Compositional matrix adjust.
 Identities = 25/78 (32%), Positives = 43/78 (55%)
 Frame = -1

Query: 1185 GEAELTIEILSDAGVKAEVLIQNNADGTYHITYSPAFPGTYTITIKYGGHPIPKFPTRVH 1244
            G+ E+   + + +G K + L+ N  DGTY + Y+P   G  ++ + Y G PIP  P +V+
Sbjct: 247  GQGEVEAILTTPSGRKLQTLVDNMKDGTYPVLYTPMEEGPQSLDVTYKGIPIPGSPFQVN 68

Query: 1245 VQPAVDTSGIKVSGPGVE 1262
                 D + ++  GPG+E
Sbjct: 67   AVAGYDANRVRAYGPGLE 14

 Score = 50.8 bits (120), Expect(2) = 1e-12,   Method: Compositional matrix adjust.
 Identities = 30/73 (41%), Positives = 38/73 (52%), Gaps = 3/73 (4%)
 Frame = -2

Query: 1499 DGTHTVHYTPATDGPYTVAVKYADQEVPRSPFKIKVLPSH---DASKVRASGPGLNASGI 1555
            DGT  V Y P   G Y V V + D+ VP SPF   + PS    D S + ASG G++  G+
Sbjct: 483  DGTVNVTYIPEFPGEYKVKVSHGDKPVPGSPFTALITPSELDPDVSSITASGYGISPEGV 304

Query: 1556 PASLPVEFTIDAR 1568
                P EF +DA 
Sbjct: 303  FIEAPSEFVVDAS 265

 Score = 42.4 bits (98), Expect(2) = 1e-12,   Method: Compositional matrix adjust.
 Identities = 23/70 (32%), Positives = 38/70 (54%)
 Frame = -1

Query: 1571 GQGLLTVQILDPEGKPKKANIRDNGDGTYTVSYLPDMSGRYTITIKYGGDEIPYSPFRIH 1630
            GQG +   +  P G+  +  + +  DGTY V Y P   G  ++ + Y G  IP SPF+++
Sbjct: 247  GQGEVEAILTTPSGRKLQTLVDNMKDGTYPVLYTPMEEGPQSLDVTYKGIPIPGSPFQVN 68

Query: 1631 ALPTGDASKC 1640
            A+   DA++ 
Sbjct: 67   AVAGYDANRV 38

 Score = 56.2 bits (134), Expect(2) = 1e-11,   Method: Compositional matrix adjust.
 Identities = 27/80 (33%), Positives = 44/80 (55%)
 Frame = -1

Query: 407 GTGDVAVVIVDPQGRRDTVEVALEDKGDNTFRCTYRPVMEGPHTVHVAFAGAPITRSPFP 466
           G G+V  ++  P GR+  ++  +++  D T+   Y P+ EGP ++ V + G PI  SPF 
Sbjct: 247 GQGEVEAILTTPSGRK--LQTLVDNMKDGTYPVLYTPMEEGPQSLDVTYKGIPIPGSPFQ 74

Query: 467 VHVAEACNPNACRASGRGLQ 486
           V+     + N  RA G GL+
Sbjct: 73  VNAVAGYDANRVRAYGPGLE 14

 Score = 34.3 bits (77), Expect(2) = 1e-11,   Method: Compositional matrix adjust.
 Identities = 23/79 (29%), Positives = 39/79 (49%), Gaps = 2/79 (2%)
 Frame = -2

Query: 323 EEAKVVPNNDKDRTYAVSYVPKVAGLHKVTVLFAGQNIERSPFEVNVGMAL--GDANKVS 380
           E++K+   N  D T  V+Y+P+  G +KV V    + +  SPF   +  +    D + ++
Sbjct: 516 EKSKINCVNXDDGTVNVTYIPEFPGEYKVKVSHGDKPVPGSPFTALITPSELDPDVSSIT 337

Query: 381 ARGPGLEPVGNVANKPTYF 399
           A G G+ P G     P+ F
Sbjct: 336 ASGYGISPEGVFIEAPSEF 280

 Score = 52.0 bits (123), Expect(2) = 3e-11,   Method: Compositional matrix adjust.
 Identities = 29/80 (36%), Positives = 41/80 (51%)
 Frame = -1

Query: 506 GSGELKVTVKGPKGTEEPVKVREAGDGVFECEYYPVVPGKYVVTITWGGYAIPRSPFEVQ 565
           G GE++  +  P G +    V    DG +   Y P+  G   + +T+ G  IP SPF+V 
Sbjct: 247 GQGEVEAILTTPSGRKLQTLVDNMKDGTYPVLYTPMEEGPQSLDVTYKGIPIPGSPFQVN 68

Query: 566 VSPEAGAQKVRAWGPGLETG 585
                 A +VRA+GPGLE G
Sbjct: 67  AVAGYDANRVRAYGPGLEGG 8

 Score = 36.6 bits (83), Expect(2) = 3e-11,   Method: Compositional matrix adjust.
 Identities = 24/90 (26%), Positives = 45/90 (50%), Gaps = 3/90 (3%)
 Frame = -2

Query: 414 VIVDPQGRRDTVEVALEDKGDNTFRCTYRPVMEGPHTVHVAFAGAPITRSPFPVHVAEA- 472
           +++DP+  +    +   +  D T   TY P   G + V V+    P+  SPF   +  + 
Sbjct: 531 LLMDPEKSK----INCVNXDDGTVNVTYIPEFPGEYKVKVSHGDKPVPGSPFTALITPSE 364

Query: 473 CNPN--ACRASGRGLQPKGVRVKEVADFKV 500
            +P+  +  ASG G+ P+GV ++  ++F V
Sbjct: 363 LDPDVSSITASGYGISPEGVFIEAPSEFVV 274

 Score = 67.0 bits (162), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 37/82 (45%), Positives = 51/82 (62%)
 Frame = -1

Query: 996  GQGQLDVRMTSPSRRPIPCKLEPGGGAEAQAVRYMPPEEGPYKVDITYDGHPVPGSPFAV 1055
            GQG+++  +T+PS R +   ++         V Y P EEGP  +D+TY G P+PGSPF V
Sbjct: 247  GQGEVEAILTTPSGRKLQTLVDNMKDG-TYPVLYTPMEEGPQSLDVTYKGIPIPGSPFQV 71

Query: 1056 EGVLPPDPSKVCAYGPGLKGGL 1077
              V   D ++V AYGPGL+GGL
Sbjct: 70   NAVAGYDANRVRAYGPGLEGGL 5

 Score = 47.4 bits (111), Expect(2) = 3e-10,   Method: Compositional matrix adjust.
 Identities = 23/55 (41%), Positives = 33/55 (60%)
 Frame = -1

Query: 1115 DGSCAVSYLPTEPGEYTINILFAEAHIPGSPFKATIQPVFDPSKVRASGPGLERG 1169
            DG+  V Y P E G  ++++ +    IPGSPF+      +D ++VRA GPGLE G
Sbjct: 172  DGTYPVLYTPMEEGPQSLDVTYKGIPIPGSPFQVNAVAGYDANRVRAYGPGLEGG 8

 Score = 37.7 bits (86), Expect(2) = 3e-10,   Method: Compositional matrix adjust.
 Identities = 25/66 (37%), Positives = 35/66 (53%), Gaps = 5/66 (7%)
 Frame = -2

Query: 1027 VRYMPPEEGPYKVDITYDGHPVPGSPFA---VEGVLPPDPSKVCAYGPGL--KGGLVGTP 1081
            V Y+P   G YKV +++   PVPGSPF        L PD S + A G G+  +G  +  P
Sbjct: 468  VTYIPEFPGEYKVKVSHGDKPVPGSPFTALITPSELDPDVSSITASGYGISPEGVFIEAP 289

Query: 1082 APFSID 1087
            + F +D
Sbjct: 288  SEFVVD 271

 Score = 64.7 bits (156), Expect = 5e-10,   Method: Compositional matrix adjust.
 Identities = 64/200 (32%), Positives = 93/200 (46%), Gaps = 13/200 (6%)
 Frame = -1

Query: 2335 EFSIWTRE-AGAGGLSIAVEGPSKAEIAFED--RKDGSCG----VSYVVQEPGD--YEVS 2385
            EF +  RE    G L IAV+GP K +    +  R +G C     VS+ +Q  G+   + S
Sbjct: 583  EFVVDAREETRVGDLDIAVDGPGKIQDKLRE*XRWNGQCDLHT*VSWGIQGEGEPRGQAS 404

Query: 2386 IKFNDEHIPDSPF-VVPVASLSDDA--RRLTVTSLQETGLKVNQPASFAVQLNGARGVID 2442
             +    H P   F   P     +    R +T  S+    ++V         L G +G ++
Sbjct: 403  TRIT-LHCPHYTF*AGP*CQQHNSVWLRNITRGSVH*GTVRVCSGRECVGPLKG-QGEVE 230

Query: 2443 ARVHTPSGAVEECYVSELDSDKHTIRFIPHENGVHSIDVKFNGAHIPGSPFKIRVGEQSQ 2502
            A + TPSG   +  V  +    + + + P E G  S+DV + G  IPGSPF++     + 
Sbjct: 229  AILTTPSGRKLQTLVDNMKDGTYPVLYTPMEEGPQSLDVTYKGIPIPGSPFQV----NAV 62

Query: 2503 AG-DPGLVSAYGPGLEGGTT 2521
            AG D   V AYGPGLEGG T
Sbjct: 61   AGYDANRVRAYGPGLEGGLT 2

 Score = 43.5 bits (101), Expect(2) = 6e-10,   Method: Compositional matrix adjust.
 Identities = 23/62 (37%), Positives = 33/62 (53%)
 Frame = -1

Query: 1675 GKGKVTCTVSTPDGAELDVDVVENHDGTFDIYYTAPEPGKYVITIRFGGEHIPNSPFHVL 1734
            G+G+V   ++TP G +L   V    DGT+ + YT  E G   + + + G  IP SPF V 
Sbjct: 247  GQGEVEAILTTPSGRKLQTLVDNMKDGTYPVLYTPMEEGPQSLDVTYKGIPIPGSPFQVN 68

Query: 1735 AC 1736
            A 
Sbjct: 67   AV 62

 Score = 40.4 bits (93), Expect(2) = 6e-10,   Method: Compositional matrix adjust.
 Identities = 22/79 (27%), Positives = 41/79 (51%)
 Frame = -2

Query: 1573 GLLTVQILDPEGKPKKANIRDNGDGTYTVSYLPDMSGRYTITIKYGGDEIPYSPFRIHAL 1632
            G+    ++DPE    K N  +  DGT  V+Y+P+  G Y + + +G   +P SPF     
Sbjct: 546  GIWI*LLMDPEKS--KINCVNXDDGTVNVTYIPEFPGEYKVKVSHGDKPVPGSPFTALIT 373

Query: 1633 PTGDASKCLVTVSIGGHGL 1651
            P+ +    + +++  G+G+
Sbjct: 372  PS-ELDPDVSSITASGYGI 319

 Score = 43.1 bits (100), Expect(2) = 1e-09,   Method: Compositional matrix adjust.
 Identities = 22/55 (40%), Positives = 34/55 (61%), Gaps = 1/55 (1%)
 Frame = -1

Query: 921 IIDN-HDYSYTVKYTAVQQGNMAVTVTYGGDPVPKSPFVVNVAPPLDLSKVKVQG 974
           ++DN  D +Y V YT +++G  ++ VTY G P+P SPF VN     D ++V+  G
Sbjct: 190 LVDNMKDGTYPVLYTPMEEGPQSLDVTYKGIPIPGSPFQVNAVAGYDANRVRAYG 26

 Score = 40.4 bits (93), Expect(2) = 1e-09,   Method: Compositional matrix adjust.
 Identities = 24/68 (35%), Positives = 33/68 (48%), Gaps = 3/68 (4%)
 Frame = -2

Query: 829 TFTVKYTPPGAGHYTIMVLFANQEIPASPFHIKVDPSH---DASKVKAEGPGLSRTGVEV 885
           T  V Y P   G Y + V   ++ +P SPF   + PS    D S + A G G+S  GV +
Sbjct: 477 TVNVTYIPEFPGEYKVKVSHGDKPVPGSPFTALITPSELDPDVSSITASGYGISPEGVFI 298

Query: 886 GKPTHFTV 893
             P+ F V
Sbjct: 297 EAPSEFVV 274

 Score = 56.6 bits (135), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 31/80 (38%), Positives = 44/80 (55%), Gaps = 1/80 (1%)
 Frame = -1

Query: 1796 KGELTGEVRMPSGKTARPNITDNKDGTITVRYAPTEKGLHQMGIKYDGNHIPGSPLQF-Y 1854
            +GE+   +  PSG+  +  + + KDGT  V Y P E+G   + + Y G  IPGSP Q   
Sbjct: 244  QGEVEAILTTPSGRKLQTLVDNMKDGTYPVLYTPMEEGPQSLDVTYKGIPIPGSPFQVNA 65

Query: 1855 VDAINSRHVSAYGPGLSHGM 1874
            V   ++  V AYGPGL  G+
Sbjct: 64   VAGYDANRVRAYGPGLEGGL 5

 Score = 38.5 bits (88), Expect(2) = 3e-07,   Method: Compositional matrix adjust.
 Identities = 25/68 (36%), Positives = 36/68 (52%), Gaps = 3/68 (4%)
 Frame = -2

Query: 2002 IGISFTPKEVGEHVVSVRKSGKHVTNSPFKILVGPSEIG-DASKVRVWGKGLSEGQTFQV 2060
            + +++ P+  GE+ V V    K V  SPF  L+ PSE+  D S +   G G+S    F  
Sbjct: 474  VNVTYIPEFPGEYKVKVSHGDKPVPGSPFTALITPSELDPDVSSITASGYGISPEGVFIE 295

Query: 2061 A--EFIVD 2066
            A  EF+VD
Sbjct: 294  APSEFVVD 271

 Score = 36.6 bits (83), Expect(2) = 3e-07,   Method: Compositional matrix adjust.
 Identities = 16/45 (35%), Positives = 25/45 (55%)
 Frame = -1

Query: 2084 KVDINCEDMEDGTCKVTYCPTEPGTYIINIKFADKHVPGSPFTVK 2128
            K+    ++M+DGT  V Y P E G   +++ +    +PGSPF V 
Sbjct: 202  KLQTLVDNMKDGTYPVLYTPMEEGPQSLDVTYKGIPIPGSPFQVN 68

 Score = 55.1 bits (131), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 31/80 (38%), Positives = 47/80 (58%)
 Frame = -1

Query: 2250 DMTAQVTSPSGKTEAAEIVEGEDSAYSVRFVPQEMGPHTVTVKYRGQHVPGSPFQFTVGP 2309
            ++ A +T+PSG+     +   +D  Y V + P E GP ++ V Y+G  +PGSPFQ  V  
Sbjct: 238  EVEAILTTPSGRKLQTLVDNMKDGTYPVLYTPMEEGPQSLDVTYKGIPIPGSPFQ--VNA 65

Query: 2310 LGEGGAHKVRAGGTGLERGV 2329
            +    A++VRA G GLE G+
Sbjct: 64   VAGYDANRVRAYGPGLEGGL 5

 Score = 54.7 bits (130), Expect = 5e-07,   Method: Compositional matrix adjust.
 Identities = 25/49 (51%), Positives = 33/49 (67%)
 Frame = -2

Query: 1900 PSKAEITCKDNKDGTCTVSYLPTAPGDYSIIVRFDDKHIPGSPFTAKIT 1948
            P K++I C +  DGT  V+Y+P  PG+Y + V   DK +PGSPFTA IT
Sbjct: 519  PEKSKINCVNXDDGTVNVTYIPEFPGEYKVKVSHGDKPVPGSPFTALIT 373

 Score = 40.8 bits (94), Expect(2) = 5e-07,   Method: Compositional matrix adjust.
 Identities = 20/50 (40%), Positives = 29/50 (58%)
 Frame = -1

Query: 829 TFTVKYTPPGAGHYTIMVLFANQEIPASPFHIKVDPSHDASKVKAEGPGL 878
           T+ V YTP   G  ++ V +    IP SPF +     +DA++V+A GPGL
Sbjct: 166 TYPVLYTPMEEGPQSLDVTYKGIPIPGSPFQVNAVAGYDANRVRAYGPGL 17

 Score = 33.1 bits (74), Expect(2) = 5e-07,   Method: Compositional matrix adjust.
 Identities = 24/80 (30%), Positives = 36/80 (45%), Gaps = 3/80 (3%)
 Frame = -2

Query: 717 IKVIPNGDGTFRCSYVPTKPIKHTIIVSWGGVNVPKSPFRVNVGEGS-HPE--RVKVYGP 773
           I  +   DGT   +Y+P  P ++ + VS G   VP SPF   +      P+   +   G 
Sbjct: 504 INCVNXDDGTVNVTYIPEFPGEYKVKVSHGDKPVPGSPFTALITPSELDPDVSSITASGY 325

Query: 774 GVEKTGLKANEPTYFTVDCS 793
           G+   G+    P+ F VD S
Sbjct: 324 GISPEGVFIEAPSEFVVDAS 265

 Score = 53.1 bits (126), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 25/49 (51%), Positives = 30/49 (61%)
 Frame = -2

Query: 2082 PSKVDINCEDMEDGTCKVTYCPTEPGTYIINIKFADKHVPGSPFTVKVT 2130
            P K  INC + +DGT  VTY P  PG Y + +   DK VPGSPFT  +T
Sbjct: 519  PEKSKINCVNXDDGTVNVTYIPEFPGEYKVKVSHGDKPVPGSPFTALIT 373

 Score = 51.2 bits (121), Expect = 6e-06,   Method: Compositional matrix adjust.
 Identities = 35/81 (43%), Positives = 43/81 (53%)
 Frame = -1

Query: 307 GVGEVLVYIEDPEGHTEEAKVVPNNDKDRTYAVSYVPKVAGLHKVTVLFAGQNIERSPFE 366
           G GEV   +  P G   +  V  +N KD TY V Y P   G   + V + G  I  SPF+
Sbjct: 247 GQGEVEAILTTPSGRKLQTLV--DNMKDGTYPVLYTPMEEGPQSLDVTYKGIPIPGSPFQ 74

Query: 367 VNVGMALGDANKVSARGPGLE 387
           VN  +A  DAN+V A GPGLE
Sbjct: 73  VNA-VAGYDANRVRAYGPGLE 14

 Score = 40.8 bits (94), Expect(2) = 1e-05,   Method: Compositional matrix adjust.
 Identities = 26/70 (37%), Positives = 35/70 (50%), Gaps = 2/70 (2%)
 Frame = -1

Query: 1391 PSEAKM-SCKDN-KDGSCTVEYIPFTPGDYDVNITFGGQPIPGSPFRXXXXXXXXXXXXX 1448
            PS  K+ +  DN KDG+  V Y P   G   +++T+ G PIPGSPF+             
Sbjct: 214  PSGRKLQTLVDNMKDGTYPVLYTPMEEGPQSLDVTYKGIPIPGSPFQVNAVAGYDANRVR 35

Query: 1449 CSGPGLGTGV 1458
              GPGL  G+
Sbjct: 34   AYGPGLEGGL 5

 Score = 28.5 bits (62), Expect(2) = 1e-05,   Method: Compositional matrix adjust.
 Identities = 26/87 (29%), Positives = 41/87 (47%), Gaps = 5/87 (5%)
 Frame = -2

Query: 1293 VLNPSGAKTDTYVTDNGDGTYRVQYTAYEEGVHLVEVLYDEVAVPKSPFRVGVTEG-CDP 1351
            +++P  +K +    D  DGT  V Y     G + V+V + +  VP SPF   +T    DP
Sbjct: 528  LMDPEKSKINCVNXD--DGTVNVTYIPEFPGEYKVKVSHGDKPVPGSPFTALITPSELDP 355

Query: 1352 --TRVRAFGPGL--EGGLVNKANRFTV 1374
              + + A G G+  EG  +   + F V
Sbjct: 354  DVSSITASGYGISPEGVFIEAPSEFVV 274

 Score = 32.7 bits (73), Expect(2) = 2e-04,   Method: Compositional matrix adjust.
 Identities = 22/72 (30%), Positives = 35/72 (48%), Gaps = 5/72 (6%)
 Frame = -2

Query: 531 DGVFECEYYPVVPGKYVVTITWGGYAIPRSPFEVQVSP---EAGAQKVRAWGPGL--ETG 585
           DG     Y P  PG+Y V ++ G   +P SPF   ++P   +     + A G G+  E  
Sbjct: 483 DGTVNVTYIPEFPGEYKVKVSHGDKPVPGSPFTALITPSELDPDVSSITASGYGISPEGV 304

Query: 586 QVGKSADFVVEA 597
            +   ++FVV+A
Sbjct: 303 FIEAPSEFVVDA 268

 Score = 32.7 bits (73), Expect(2) = 2e-04,   Method: Compositional matrix adjust.
 Identities = 24/70 (34%), Positives = 35/70 (50%), Gaps = 2/70 (2%)
 Frame = -1

Query: 612 PSQAKIE--CDDKGDGSCDVRYWPTEPGEYAVHVICDDEDIRDSPFIAHIQPAPPDCFPD 669
           PS  K++   D+  DG+  V Y P E G  ++ V      I  SPF  +   A      +
Sbjct: 214 PSGRKLQTLVDNMKDGTYPVLYTPMEEGPQSLDVTYKGIPIPGSPFQVN---AVAGYDAN 44

Query: 670 KVKAFGPGLE 679
           +V+A+GPGLE
Sbjct: 43  RVRAYGPGLE 14

 Score = 33.9 bits (76), Expect(2) = 2e-04,   Method: Compositional matrix adjust.
 Identities = 26/69 (37%), Positives = 35/69 (50%), Gaps = 3/69 (4%)
 Frame = -1

Query: 1889 GEGGLSLAVEGPSKAEI-TCKDN-KDGTCTVSYLPTAPGDYSIIVRFDDKHIPGSPFTAK 1946
            G+G +   +  PS  ++ T  DN KDGT  V Y P   G  S+ V +    IPGSPF   
Sbjct: 247  GQGEVEAILTTPSGRKLQTLVDNMKDGTYPVLYTPMEEGPQSLDVTYKGIPIPGSPFQVN 68

Query: 1947 -ITGDDSMR 1954
             + G D+ R
Sbjct: 67   AVAGYDANR 41

 Score = 31.2 bits (69), Expect(2) = 2e-04,   Method: Compositional matrix adjust.
 Identities = 18/81 (22%), Positives = 35/81 (43%), Gaps = 6/81 (7%)
 Frame = -2

Query: 1809 KTARPNITDNKDGTITVRYAPTEKGLHQMGIKYDGNHIPGSPLQFYVDA------INSRH 1862
            + ++ N  +  DGT+ V Y P   G +++ + +    +PGSP    +        ++S  
Sbjct: 516  EKSKINCVNXDDGTVNVTYIPEFPGEYKVKVSHGDKPVPGSPFTALITPSELDPDVSSIT 337

Query: 1863 VSAYGPGLSHGMVNKPATFTI 1883
             S YG       +  P+ F +
Sbjct: 336  ASGYGISPEGVFIEAPSEFVV 274

 Score = 36.6 bits (83), Expect = 0.15,   Method: Compositional matrix adjust.
 Identities = 24/81 (29%), Positives = 39/81 (48%)
 Frame = -1

Query: 1977 QLTASIRAPSGNEEPCLLKRLPNRHIGISFTPKEVGEHVVSVRKSGKHVTNSPFKILVGP 2036
            ++ A +  PSG +   L+  + +    + +TP E G   + V   G  +  SPF+  V  
Sbjct: 238  EVEAILTTPSGRKLQTLVDNMKDGTYPVLYTPMEEGPQSLDVTYKGIPIPGSPFQ--VNA 65

Query: 2037 SEIGDASKVRVWGKGLSEGQT 2057
                DA++VR +G GL  G T
Sbjct: 64   VAGYDANRVRAYGPGLEGGLT 2

 Score = 34.3 bits (77), Expect = 0.68,   Method: Compositional matrix adjust.
 Identities = 20/54 (37%), Positives = 30/54 (55%), Gaps = 1/54 (1%)
 Frame = -2

Query: 2546 PSKVQLDCRECPEGHV-VTYTPMAPGNYLIAIKYGGPQHIVGSPFKAKVTGPRL 2598
            P K +++C    +G V VTY P  PG Y + + +G  + + GSPF A +T   L
Sbjct: 519  PEKSKINCVNXDDGTVNVTYIPEFPGEYKVKVSHGD-KPVPGSPFTALITPSEL 361

 Score = 32.7 bits (73), Expect = 2.2,   Method: Compositional matrix adjust.
 Identities = 14/42 (33%), Positives = 23/42 (54%)
 Frame = -2

Query: 1693 VDVVENHDGTFDIYYTAPEPGKYVITIRFGGEHIPNSPFHVL 1734
            ++ V   DGT ++ Y    PG+Y + +  G + +P SPF  L
Sbjct: 504  INCVNXDDGTVNVTYIPEFPGEYKVKVSHGDKPVPGSPFTAL 379

 Score = 32.3 bits (72), Expect = 2.6,   Method: Compositional matrix adjust.
 Identities = 17/43 (39%), Positives = 24/43 (55%)
 Frame = -1

Query: 2682 EVYVKHMGNRVYNVTYTVKEKGDYILIVKWGDESVPGSPFKVN 2724
            +  V +M +  Y V YT  E+G   L V +    +PGSPF+VN
Sbjct: 196  QTLVDNMKDGTYPVLYTPMEEGPQSLDVTYKGIPIPGSPFQVN 68

 Score = 31.2 bits (69), Expect = 5.6,   Method: Compositional matrix adjust.
 Identities = 15/28 (53%), Positives = 19/28 (67%)
 Frame = -2

Query: 2694 NVTYTVKEKGDYILIVKWGDESVPGSPF 2721
            NVTY  +  G+Y + V  GD+ VPGSPF
Sbjct: 471  NVTYIPEFPGEYKVKVSHGDKPVPGSPF 388
>19002
          Length = 842

 Score =  101 bits (252), Expect = 4e-21,   Method: Composition-based stats.
 Identities = 64/195 (32%), Positives = 102/195 (52%), Gaps = 3/195 (1%)
 Frame = -2

Query: 67  DGLRLIALLEVLSQKRMYRKFHPRPNFRQMKLENVSVALEFLEREHIKLVSIDSKAIVDG 126
           DG  L+ LLEV  +  +      +   R   LENV  AL FL  + + L ++ +  IVDG
Sbjct: 841 DGKMLMKLLEVRVRGEIASDX--KGKMRIHCLENVDKALTFLHEQRVHLENMGAHDIVDG 668

Query: 127 NLKLILGLIWTLILHYSISMPMWEDEDDEDARKQTPKQRLLGWIQNKV---PQLPITNFN 183
           + +L LGLIWT+IL + I   M E+ D+ + +  + K  LL W Q K    P + + NF 
Sbjct: 667 SSRLTLGLIWTIILRFQIQDIMIEEVDNSETK--SAKDALLLWCQMKTAGYPNVNVRNFT 494

Query: 184 RDWQDGKALGALVDNCAPGLCPDWEAWDPNQPVQNAREAMQQADDWLGVPQVIAPEEIVD 243
             W+DG A  A++    P L   ++    +  +QN + A   A+D LG+  ++ PE++  
Sbjct: 493 TSWRDGLAFNAIIHKHRPDLV-QYDRLHKSSAIQNLQNAFTVAEDKLGLTALLEPEDVNV 317

Query: 244 PNVDEHSVMTYLSQF 258
              DE S++TY+  +
Sbjct: 316 EYPDEKSIITYVVTY 272
>05081
          Length = 981

 Score = 87.8 bits (216), Expect = 6e-17,   Method: Compositional matrix adjust.
 Identities = 43/94 (45%), Positives = 57/94 (60%), Gaps = 1/94 (1%)
 Frame = -1

Query: 2629 IPKFSSDASKVVTRGPGLSQAFVGQKNSFTVDCSKAGTNMMMVGVHGPK-TPCEEVYVKH 2687
            I +F  DASKVV +G GL +AF  +  +F VD   AG  ++ VG+  P   P  E+ VK 
Sbjct: 975  IRRFRGDASKVVAKGQGLKKAFTNRLQTFQVDVKDAGEALLQVGMIAPSGKPEAELSVKK 796

Query: 2688 MGNRVYNVTYTVKEKGDYILIVKWGDESVPGSPF 2721
              N  Y + Y V E GD++L VKWGD+ +PGSPF
Sbjct: 795  TTNTSYTINYKVTEIGDHVLHVKWGDDDIPGSPF 694

 Score = 59.7 bits (143), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 33/90 (36%), Positives = 54/90 (60%), Gaps = 1/90 (1%)
 Frame = -1

Query: 1539 DASKVRASGPGLNASGIPASLPVEFTIDARDAGQGLLTVQILDPEGKPK-KANIRDNGDG 1597
            DASKV A G GL  +    +    F +D +DAG+ LL V ++ P GKP+ + +++   + 
Sbjct: 957  DASKVVAKGQGLKKA--FTNRLQTFQVDVKDAGEALLQVGMIAPSGKPEAELSVKKTTNT 784

Query: 1598 TYTVSYLPDMSGRYTITIKYGGDEIPYSPF 1627
            +YT++Y     G + + +K+G D+IP SPF
Sbjct: 783  SYTINYKVTEIGDHVLHVKWGDDDIPGSPF 694

 Score = 58.9 bits (141), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 32/88 (36%), Positives = 49/88 (55%), Gaps = 3/88 (3%)
 Frame = -1

Query: 1859 NSRHVSAYGPGLSHGMVNKPATFTIVTKDAGEGGLSLAVEGPS---KAEITCKDNKDGTC 1915
            ++  V A G GL     N+  TF +  KDAGE  L + +  PS   +AE++ K   + + 
Sbjct: 957  DASKVVAKGQGLKKAFTNRLQTFQVDVKDAGEALLQVGMIAPSGKPEAELSVKKTTNTSY 778

Query: 1916 TVSYLPTAPGDYSIIVRFDDKHIPGSPF 1943
            T++Y  T  GD+ + V++ D  IPGSPF
Sbjct: 777  TINYKVTEIGDHVLHVKWGDDDIPGSPF 694

 Score = 55.5 bits (132), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 29/91 (31%), Positives = 53/91 (58%), Gaps = 3/91 (3%)
 Frame = -1

Query: 2040 GDASKVRVWGKGLSEGQTFQVAEFIVDTRNAGYGGLGLSIEGPS---KVDINCEDMEDGT 2096
            GDASKV   G+GL +  T ++  F VD ++AG   L + +  PS   + +++ +   + +
Sbjct: 960  GDASKVVAKGQGLKKAFTNRLQTFQVDVKDAGEALLQVGMIAPSGKPEAELSVKKTTNTS 781

Query: 2097 CKVTYCPTEPGTYIINIKFADKHVPGSPFTV 2127
              + Y  TE G +++++K+ D  +PGSPF +
Sbjct: 780  YTINYKVTEIGDHVLHVKWGDDDIPGSPFVL 688

 Score = 53.1 bits (126), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 29/83 (34%), Positives = 45/83 (54%), Gaps = 1/83 (1%)
 Frame = -1

Query: 1449 CSGPGLGTGVRARVPQTFTVDCSQAGRAPLQVAVLGPTGVAEP-VEVRDNGDGTHTVHYT 1507
              G GL      R+ QTF VD   AG A LQV ++ P+G  E  + V+   + ++T++Y 
Sbjct: 939  AKGQGLKKAFTNRL-QTFQVDVKDAGEALLQVGMIAPSGKPEAELSVKKTTNTSYTINYK 763

Query: 1508 PATDGPYTVAVKYADQEVPRSPF 1530
                G + + VK+ D ++P SPF
Sbjct: 762  VTEIGDHVLHVKWGDDDIPGSPF 694

 Score = 52.8 bits (125), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 30/92 (32%), Positives = 50/92 (54%), Gaps = 3/92 (3%)
 Frame = -1

Query: 2312 EGGAHKVRAGGTGLERGVAGVPAEFSIWTREAGAGGLSIAVEGPS---KAEIAFEDRKDG 2368
             G A KV A G GL++        F +  ++AG   L + +  PS   +AE++ +   + 
Sbjct: 963  RGDASKVVAKGQGLKKAFTNRLQTFQVDVKDAGEALLQVGMIAPSGKPEAELSVKKTTNT 784

Query: 2369 SCGVSYVVQEPGDYEVSIKFNDEHIPDSPFVV 2400
            S  ++Y V E GD+ + +K+ D+ IP SPFV+
Sbjct: 783  SYTINYKVTEIGDHVLHVKWGDDDIPGSPFVL 688

 Score = 52.0 bits (123), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 29/87 (33%), Positives = 47/87 (54%), Gaps = 1/87 (1%)
 Frame = -1

Query: 1155 DPSKVRASGPGLERGKAGEAATFTVDCSEAGEAELTIEILSDAGV-KAEVLIQNNADGTY 1213
            D SKV A G GL++       TF VD  +AGEA L + +++ +G  +AE+ ++   + +Y
Sbjct: 957  DASKVVAKGQGLKKAFTNRLQTFQVDVKDAGEALLQVGMIAPSGKPEAELSVKKTTNTSY 778

Query: 1214 HITYSPAFPGTYTITIKYGGHPIPKFP 1240
             I Y     G + + +K+G   IP  P
Sbjct: 777  TINYKVTEIGDHVLHVKWGDDDIPGSP 697

 Score = 47.0 bits (110), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 26/88 (29%), Positives = 41/88 (46%), Gaps = 3/88 (3%)
 Frame = -1

Query: 1062 DPSKVCAYGPGLKGGLVGTPAPFSIDTKXXXXXXXXXXVEGPC---EAKIECQDNGDGSC 1118
            D SKV A G GLK         F +D K          +  P    EA++  +   + S 
Sbjct: 957  DASKVVAKGQGLKKAFTNRLQTFQVDVKDAGEALLQVGMIAPSGKPEAELSVKKTTNTSY 778

Query: 1119 AVSYLPTEPGEYTINILFAEAHIPGSPF 1146
             ++Y  TE G++ +++ + +  IPGSPF
Sbjct: 777  TINYKVTEIGDHVLHVKWGDDDIPGSPF 694

 Score = 46.6 bits (109), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 32/94 (34%), Positives = 48/94 (51%)
 Frame = -1

Query: 867 DASKVKAEGPGLSRTGVEVGKPTHFTVLTKGAGKAKLDVHFAGAAKGEAVRDFEIIDNHD 926
           DASKV A+G GL +      +   F V  K AG+A L V    A  G+   +  +    +
Sbjct: 957 DASKVVAKGQGLKKAFTN--RLQTFQVDVKDAGEALLQVGMI-APSGKPEAELSVKKTTN 787

Query: 927 YSYTVKYTAVQQGNMAVTVTYGGDPVPKSPFVVN 960
            SYT+ Y   + G+  + V +G D +P SPFV++
Sbjct: 786 TSYTINYKVTEIGDHVLHVKWGDDDIPGSPFVLS 685

 Score = 43.9 bits (102), Expect = 9e-04,   Method: Compositional matrix adjust.
 Identities = 27/88 (30%), Positives = 40/88 (45%), Gaps = 3/88 (3%)
 Frame = -1

Query: 1350 DPTRVRAFGPGLEGGLVNKANRFTVXXXXXXXXXXXXXXXXPS---EAKMSCKDNKDGSC 1406
            D ++V A G GL+    N+   F V                PS   EA++S K   + S 
Sbjct: 957  DASKVVAKGQGLKKAFTNRLQTFQVDVKDAGEALLQVGMIAPSGKPEAELSVKKTTNTSY 778

Query: 1407 TVEYIPFTPGDYDVNITFGGQPIPGSPF 1434
            T+ Y     GD+ +++ +G   IPGSPF
Sbjct: 777  TINYKVTEIGDHVLHVKWGDDDIPGSPF 694

 Score = 41.6 bits (96), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 26/92 (28%), Positives = 46/92 (50%)
 Frame = -1

Query: 374 GDANKVSARGPGLEPVGNVANKPTYFDIYTAGAGTGDVAVVIVDPQGRRDTVEVALEDKG 433
           GDA+KV A+G GL+      N+   F +    AG   + V ++ P G+ +  E++++   
Sbjct: 960 GDASKVVAKGQGLKKA--FTNRLQTFQVDVKDAGEALLQVGMIAPSGKPEA-ELSVKKTT 790

Query: 434 DNTFRCTYRPVMEGPHTVHVAFAGAPITRSPF 465
           + ++   Y+    G H +HV +    I  SPF
Sbjct: 789 NTSYTINYKVTEIGDHVLHVKWGDDDIPGSPF 694

 Score = 38.1 bits (87), Expect = 0.052,   Method: Compositional matrix adjust.
 Identities = 24/74 (32%), Positives = 41/74 (55%), Gaps = 1/74 (1%)
 Frame = -1

Query: 2231 RLGSFGSITRQQEGEASSQDMTAQVTSPSGKTEA-AEIVEGEDSAYSVRFVPQEMGPHTV 2289
            RL +F  +  +  GEA  Q     + +PSGK EA   + +  +++Y++ +   E+G H +
Sbjct: 903  RLQTF-QVDVKDAGEALLQ---VGMIAPSGKPEAELSVKKTTNTSYTINYKVTEIGDHVL 736

Query: 2290 TVKYRGQHVPGSPF 2303
             VK+    +PGSPF
Sbjct: 735  HVKWGDDDIPGSPF 694

 Score = 36.6 bits (83), Expect = 0.13,   Method: Compositional matrix adjust.
 Identities = 26/84 (30%), Positives = 39/84 (46%), Gaps = 1/84 (1%)
 Frame = -1

Query: 480 ASGRGLQPKGVRVKEVADFKVFTKGAGSGELKVTVKGPKGT-EEPVKVREAGDGVFECEY 538
           A G+GL  K      +  F+V  K AG   L+V +  P G  E  + V++  +  +   Y
Sbjct: 939 AKGQGL--KKAFTNRLQTFQVDVKDAGEALLQVGMIAPSGKPEAELSVKKTTNTSYTINY 766

Query: 539 YPVVPGKYVVTITWGGYAIPRSPF 562
                G +V+ + WG   IP SPF
Sbjct: 765 KVTEIGDHVLHVKWGDDDIPGSPF 694

 Score = 36.6 bits (83), Expect = 0.14,   Method: Compositional matrix adjust.
 Identities = 30/103 (29%), Positives = 44/103 (42%), Gaps = 6/103 (5%)
 Frame = -1

Query: 572 AQKVRAWGPGLETGQVGKSADFVVEAIGTEVGTLGFSIEGPS---QAKIECDDKGDGSCD 628
           A KV A G GL+     +   F V+        L   +  PS   +A++      + S  
Sbjct: 954 ASKVVAKGQGLKKAFTNRLQTFQVDVKDAGEALLQVGMIAPSGKPEAELSVKKTTNTSYT 775

Query: 629 VRYWPTEPGEYAVHVICDDEDIRDSPFIAHIQPA---PPDCFP 668
           + Y  TE G++ +HV   D+DI  SPF+     A   P   FP
Sbjct: 774 INYKVTEIGDHVLHVKWGDDDIPGSPFVLST*TA*FPPETSFP 646

 Score = 35.8 bits (81), Expect = 0.24,   Method: Compositional matrix adjust.
 Identities = 25/87 (28%), Positives = 42/87 (48%), Gaps = 1/87 (1%)
 Frame = -1

Query: 670 KVKAFGPGLEPTGCIVDRPAEFTIDARAAGKGDLKLYAQDADGCP-IDIKVIPNGDGTFR 728
           KV A G GL+      +R   F +D + AG+  L++      G P  ++ V    + ++ 
Sbjct: 948 KVVAKGQGLKK--AFTNRLQTFQVDVKDAGEALLQVGMIAPSGKPEAELSVKKTTNTSYT 775

Query: 729 CSYVPTKPIKHTIIVSWGGVNVPKSPF 755
            +Y  T+   H + V WG  ++P SPF
Sbjct: 774 INYKVTEIGDHVLHVKWGDDDIPGSPF 694

 Score = 33.5 bits (75), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 28/92 (30%), Positives = 42/92 (45%), Gaps = 2/92 (2%)
 Frame = -1

Query: 966  DLSKV--KVQGLNSKVAVGQEQAFSVNTRGAGGQGQLDVRMTSPSRRPIPCKLEPGGGAE 1023
            D SKV  K QGL  K    + Q F V+ + AG +  L V M +PS +P            
Sbjct: 957  DASKVVAKGQGLK-KAFTNRLQTFQVDVKDAG-EALLQVGMIAPSGKPEAELSVKKTTNT 784

Query: 1024 AQAVRYMPPEEGPYKVDITYDGHPVPGSPFAV 1055
            +  + Y   E G + + + +    +PGSPF +
Sbjct: 783  SYTINYKVTEIGDHVLHVKWGDDDIPGSPFVL 688

 Score = 32.7 bits (73), Expect = 2.0,   Method: Compositional matrix adjust.
 Identities = 26/78 (33%), Positives = 38/78 (48%), Gaps = 5/78 (6%)
 Frame = -1

Query: 2421 GLK---VNQPASFAVQLNGA-RGVIDARVHTPSGAVE-ECYVSELDSDKHTIRFIPHENG 2475
            GLK    N+  +F V +  A   ++   +  PSG  E E  V +  +  +TI +   E G
Sbjct: 927  GLKKAFTNRLQTFQVDVKDAGEALLQVGMIAPSGKPEAELSVKKTTNTSYTINYKVTEIG 748

Query: 2476 VHSIDVKFNGAHIPGSPF 2493
             H + VK+    IPGSPF
Sbjct: 747  DHVLHVKWGDDDIPGSPF 694

 Score = 31.2 bits (69), Expect = 5.6,   Method: Compositional matrix adjust.
 Identities = 18/54 (33%), Positives = 28/54 (51%), Gaps = 1/54 (1%)
 Frame = -1

Query: 1978 LTASIRAPSGNEEPCL-LKRLPNRHIGISFTPKEVGEHVVSVRKSGKHVTNSPF 2030
            L   + APSG  E  L +K+  N    I++   E+G+HV+ V+     +  SPF
Sbjct: 855  LQVGMIAPSGKPEAELSVKKTTNTSYTINYKVTEIGDHVLHVKWGDDDIPGSPF 694
>29755
          Length = 460

 Score = 63.5 bits (153), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 26/45 (57%), Positives = 39/45 (86%)
 Frame = +3

Query: 2681 EEVYVKHMGNRVYNVTYTVKEKGDYILIVKWGDESVPGSPFKVNV 2725
            +E+ VK++G+  YN+ YTVK++G Y+LIV+WGDE++PGSPF V+V
Sbjct: 3    DELTVKYVGSGQYNINYTVKQQGSYMLIVRWGDENIPGSPFAVDV 137

 Score = 38.9 bits (89), Expect = 0.027,   Method: Compositional matrix adjust.
 Identities = 18/47 (38%), Positives = 26/47 (55%)
 Frame = +3

Query: 1904 EITCKDNKDGTCTVSYLPTAPGDYSIIVRFDDKHIPGSPFTAKITGD 1950
            E+T K    G   ++Y     G Y +IVR+ D++IPGSPF   +  D
Sbjct: 6    ELTVKYVGSGQYNINYTVKQQGSYMLIVRWGDENIPGSPFAVDVI*D 146

 Score = 38.5 bits (88), Expect = 0.033,   Method: Compositional matrix adjust.
 Identities = 15/33 (45%), Positives = 23/33 (69%)
 Frame = +3

Query: 1701 GTFDIYYTAPEPGKYVITIRFGGEHIPNSPFHV 1733
            G ++I YT  + G Y++ +R+G E+IP SPF V
Sbjct: 33   GQYNINYTVKQQGSYMLIVRWGDENIPGSPFAV 131

 Score = 37.7 bits (86), Expect = 0.066,   Method: Compositional matrix adjust.
 Identities = 14/46 (30%), Positives = 27/46 (58%)
 Frame = +3

Query: 1490 EPVEVRDNGDGTHTVHYTPATDGPYTVAVKYADQEVPRSPFKIKVL 1535
            + + V+  G G + ++YT    G Y + V++ D+ +P SPF + V+
Sbjct: 3    DELTVKYVGSGQYNINYTVKQQGSYMLIVRWGDENIPGSPFAVDVI 140

 Score = 36.2 bits (82), Expect = 0.20,   Method: Compositional matrix adjust.
 Identities = 19/49 (38%), Positives = 27/49 (55%), Gaps = 5/49 (10%)
 Frame = +3

Query: 929 YTVKYTAVQQGNMAVTVTYGGDPVPKSPFVVNV-----APPLDLSKVKV 972
           Y + YT  QQG+  + V +G + +P SPF V+V     A  LDL+   V
Sbjct: 39  YNINYTVKQQGSYMLIVRWGDENIPGSPFAVDVI*DFPAAHLDLTNSSV 185

 Score = 35.8 bits (81), Expect = 0.26,   Method: Compositional matrix adjust.
 Identities = 12/35 (34%), Positives = 23/35 (65%)
 Frame = +3

Query: 2095 GTCKVTYCPTEPGTYIINIKFADKHVPGSPFTVKV 2129
            G   + Y   + G+Y++ +++ D+++PGSPF V V
Sbjct: 33   GQYNINYTVKQQGSYMLIVRWGDENIPGSPFAVDV 137

 Score = 35.4 bits (80), Expect = 0.33,   Method: Compositional matrix adjust.
 Identities = 14/35 (40%), Positives = 23/35 (65%)
 Frame = +3

Query: 2368 GSCGVSYVVQEPGDYEVSIKFNDEHIPDSPFVVPV 2402
            G   ++Y V++ G Y + +++ DE+IP SPF V V
Sbjct: 33   GQYNINYTVKQQGSYMLIVRWGDENIPGSPFAVDV 137

 Score = 33.9 bits (76), Expect = 0.99,   Method: Compositional matrix adjust.
 Identities = 14/37 (37%), Positives = 21/37 (56%)
 Frame = +3

Query: 723 GDGTFRCSYVPTKPIKHTIIVSWGGVNVPKSPFRVNV 759
           G G +  +Y   +   + +IV WG  N+P SPF V+V
Sbjct: 27  GSGQYNINYTVKQQGSYMLIVRWGDENIPGSPFAVDV 137

 Score = 31.6 bits (70), Expect = 4.8,   Method: Compositional matrix adjust.
 Identities = 15/45 (33%), Positives = 22/45 (48%)
 Frame = +3

Query: 522 EPVKVREAGDGVFECEYYPVVPGKYVVTITWGGYAIPRSPFEVQV 566
           + + V+  G G +   Y     G Y++ + WG   IP SPF V V
Sbjct: 3   DELTVKYVGSGQYNINYTVKQQGSYMLIVRWGDENIPGSPFAVDV 137
>19147
          Length = 474

 Score = 63.2 bits (152), Expect = 2e-09,   Method: Composition-based stats.
 Identities = 36/100 (36%), Positives = 56/100 (56%), Gaps = 3/100 (3%)
 Frame = +1

Query: 107 FLEREHIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWEDEDDEDARKQTPKQRL 166
           ++  + +KLVSI ++ IVDGN+K+ LG+IWT+IL ++I         D    + T K+ L
Sbjct: 49  YIASKGVKLVSIGAEEIVDGNVKMTLGMIWTIILRFAIQ--------DITVEELTAKEGL 204

Query: 167 LGWIQNKVP---QLPITNFNRDWQDGKALGALVDNCAPGL 203
           L W Q K      + + NF+  ++DG A  AL+    P L
Sbjct: 205 LLWCQRKTAPYKNVNVQNFHLSFKDGLAFCALIHRHRPEL 324
>19154
          Length = 512

 Score = 61.6 bits (148), Expect = 4e-09,   Method: Compositional matrix adjust.
 Identities = 51/146 (34%), Positives = 69/146 (47%), Gaps = 4/146 (2%)
 Frame = +2

Query: 987  FSVNTRGAGGQGQLDVRMTSPSRRPIPCKLEPGGGAEAQAVRYMPPEEGPYKVDITYDGH 1046
            FSV T  +G   Q  VR+ SPS + +P  +          + Y P E G +++ +TY+  
Sbjct: 77   FSVETSRSGKCEQ-TVRIVSPSGQSVPVDVTETS-TYGYNITYQPSESGQHRIFLTYNSL 250

Query: 1047 PVPGSPFA---VEGVLPPDPSKVCAYGPGLKGGLVGTPAPFSIDTKXXXXXXXXXXVEGP 1103
             +PGSPF     EGVLPP      AYG GL  G     A F ID +          V+GP
Sbjct: 251  ELPGSPFTQEISEGVLPP------AYGEGLHRGEEDKAAIFYIDAR-GLTGEPSVQVDGP 409

Query: 1104 CE-AKIECQDNGDGSCAVSYLPTEPG 1128
               AK   +   DG  +V+Y+P E G
Sbjct: 410  NSIAKCSIEAQPDGQYSVTYIPVEVG 487

 Score = 58.5 bits (140), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 45/142 (31%), Positives = 65/142 (45%), Gaps = 1/142 (0%)
 Frame = +2

Query: 497 DFKVFTKGAGSGELKVTVKGPKGTEEPVKVREAGDGVFECEYYPVVPGKYVVTITWGGYA 556
           DF V T  +G  E  V +  P G   PV V E     +   Y P   G++ + +T+    
Sbjct: 74  DFSVETSRSGKCEQTVRIVSPSGQSVPVDVTETSTYGYNITYQPSESGQHRIFLTYNSLE 253

Query: 557 IPRSPFEVQVSPEAGAQKVRAWGPGLETGQVGKSADFVVEAIGTEVGTLGFSIEGP-SQA 615
           +P SPF  ++S         A+G GL  G+  K+A F ++A G   G     ++GP S A
Sbjct: 254 LPGSPFTQEISEGVLPP---AYGEGLHRGEEDKAAIFYIDARGL-TGEPSVQVDGPNSIA 421

Query: 616 KIECDDKGDGSCDVRYWPTEPG 637
           K   + + DG   V Y P E G
Sbjct: 422 KCSIEAQPDGQYSVTYIPVEVG 487

 Score = 55.8 bits (133), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 41/131 (31%), Positives = 65/131 (49%), Gaps = 1/131 (0%)
 Frame = +2

Query: 1796 KGELTGEVRMPSGKTARPNITDNKDGTITVRYAPTEKGLHQMGIKYDGNHIPGSPLQFYV 1855
            K E T  +  PSG++   ++T+       + Y P+E G H++ + Y+   +PGSP  F  
Sbjct: 104  KCEQTVRIVSPSGQSVPVDVTETSTYGYNITYQPSESGQHRIFLTYNSLELPGSP--FTQ 277

Query: 1856 DAINSRHVSAYGPGLSHGMVNKPATFTIVTKDAGEGGLSLAVEGP-SKAEITCKDNKDGT 1914
            +        AYG GL  G  +K A F I  +    G  S+ V+GP S A+ + +   DG 
Sbjct: 278  EISEGVLPPAYGEGLHRGEEDKAAIFYIDARGL-TGEPSVQVDGPNSIAKCSIEAQPDGQ 454

Query: 1915 CTVSYLPTAPG 1925
             +V+Y+P   G
Sbjct: 455  YSVTYIPVEVG 487

 Score = 55.5 bits (132), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 43/132 (32%), Positives = 64/132 (48%), Gaps = 1/132 (0%)
 Frame = +2

Query: 2250 DMTAQVTSPSGKTEAAEIVEGEDSAYSVRFVPQEMGPHTVTVKYRGQHVPGSPFQFTVGP 2309
            + T ++ SPSG++   ++ E     Y++ + P E G H + + Y    +PGSPF      
Sbjct: 110  EQTVRIVSPSGQSVPVDVTETSTYGYNITYQPSESGQHRIFLTYNSLELPGSPF---TQE 280

Query: 2310 LGEGGAHKVRAGGTGLERGVAGVPAEFSIWTREAGAGGLSIAVEGP-SKAEIAFEDRKDG 2368
            + EG      A G GL RG     A F I  R    G  S+ V+GP S A+ + E + DG
Sbjct: 281  ISEGVLPP--AYGEGLHRGEEDKAAIFYIDAR-GLTGEPSVQVDGPNSIAKCSIEAQPDG 451

Query: 2369 SCGVSYVVQEPG 2380
               V+Y+  E G
Sbjct: 452  QYSVTYIPVEVG 487

 Score = 53.9 bits (128), Expect = 9e-07,   Method: Compositional matrix adjust.
 Identities = 40/130 (30%), Positives = 65/130 (50%), Gaps = 2/130 (1%)
 Frame = +2

Query: 2444 RVHTPSGAVEECYVSELDSDKHTIRFIPHENGVHSIDVKFNGAHIPGSPFKIRVGEQSQA 2503
            R+ +PSG      V+E  +  + I + P E+G H I + +N   +PGSPF   + E    
Sbjct: 122  RIVSPSGQSVPVDVTETSTYGYNITYQPSESGQHRIFLTYNSLELPGSPFTQEISEGV-- 295

Query: 2504 GDPGLVSAYGPGLEGGTTGVSSEFIVNTQNAGSGALSVTIDGPSKV-QLDCRECPEG-HV 2561
                L  AYG GL  G    ++ F ++ +   +G  SV +DGP+ + +      P+G + 
Sbjct: 296  ----LPPAYGEGLHRGEEDKAAIFYIDARGL-TGEPSVQVDGPNSIAKCSIEAQPDGQYS 460

Query: 2562 VTYTPMAPGN 2571
            VTY P+  G+
Sbjct: 461  VTYIPVEVGS 490

 Score = 52.0 bits (123), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 43/144 (29%), Positives = 69/144 (47%), Gaps = 4/144 (2%)
 Frame = +2

Query: 1466 FTVDCSQAGRAPLQVAVLGPTGVAEPVEVRDNGDGTHTVHYTPATDGPYTVAVKYADQEV 1525
            F+V+ S++G+    V ++ P+G + PV+V +     + + Y P+  G + + + Y   E+
Sbjct: 77   FSVETSRSGKCEQTVRIVSPSGQSVPVDVTETSTYGYNITYQPSESGQHRIFLTYNSLEL 256

Query: 1526 PRSPFKIK----VLPSHDASKVRASGPGLNASGIPASLPVEFTIDARDAGQGLLTVQILD 1581
            P SPF  +    VLP        A G GL+           F IDAR    G  +VQ+  
Sbjct: 257  PGSPFTQEISEGVLPP-------AYGEGLHRG--EEDKAAIFYIDARGL-TGEPSVQVDG 406

Query: 1582 PEGKPKKANIRDNGDGTYTVSYLP 1605
            P     K +I    DG Y+V+Y+P
Sbjct: 407  PNSI-AKCSIEAQPDGQYSVTYIP 475

 Score = 50.4 bits (119), Expect = 8e-06,   Method: Compositional matrix adjust.
 Identities = 38/145 (26%), Positives = 64/145 (44%), Gaps = 1/145 (0%)
 Frame = +2

Query: 1965 DVSLKITEGDLSQLTASIRAPSGNEEPCLLKRLPNRHIGISFTPKEVGEHVVSVRKSGKH 2024
            D S++ +     + T  I +PSG   P  +         I++ P E G+H + +  +   
Sbjct: 74   DFSVETSRSGKCEQTVRIVSPSGQSVPVDVTETSTYGYNITYQPSESGQHRIFLTYNSLE 253

Query: 2025 VTNSPFKILVGPSEIGDASKVRVWGKGLSEGQTFQVAEFIVDTRNAGYGGLGLSIEGPSK 2084
            +  SPF       EI +      +G+GL  G+  + A F +D R    G   + ++GP+ 
Sbjct: 254  LPGSPFT-----QEISEGVLPPAYGEGLHRGEEDKAAIFYIDARGLT-GEPSVQVDGPNS 415

Query: 2085 V-DINCEDMEDGTCKVTYCPTEPGT 2108
            +   + E   DG   VTY P E G+
Sbjct: 416  IAKCSIEAQPDGQYSVTYIPVEVGS 490

 Score = 46.6 bits (109), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 33/106 (31%), Positives = 55/106 (51%), Gaps = 1/106 (0%)
 Frame = +2

Query: 1120 VSYLPTEPGEYTINILFAEAHIPGSPFKATI-QPVFDPSKVRASGPGLERGKAGEAATFT 1178
            ++Y P+E G++ I + +    +PGSPF   I + V  P    A G GL RG+  +AA F 
Sbjct: 191  ITYQPSESGQHRIFLTYNSLELPGSPFTQEISEGVLPP----AYGEGLHRGEEDKAAIFY 358

Query: 1179 VDCSEAGEAELTIEILSDAGVKAEVLIQNNADGTYHITYSPAFPGT 1224
            +D +     E ++++     + A+  I+   DG Y +TY P   G+
Sbjct: 359  ID-ARGLTGEPSVQVDGPNSI-AKCSIEAQPDGQYSVTYIPVEVGS 490

 Score = 43.5 bits (101), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 19/67 (28%), Positives = 38/67 (56%)
 Frame = +2

Query: 1561 VEFTIDARDAGQGLLTVQILDPEGKPKKANIRDNGDGTYTVSYLPDMSGRYTITIKYGGD 1620
            ++F+++   +G+   TV+I+ P G+    ++ +     Y ++Y P  SG++ I + Y   
Sbjct: 71   LDFSVETSRSGKCEQTVRIVSPSGQSVPVDVTETSTYGYNITYQPSESGQHRIFLTYNSL 250

Query: 1621 EIPYSPF 1627
            E+P SPF
Sbjct: 251  ELPGSPF 271

 Score = 43.1 bits (100), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 41/147 (27%), Positives = 64/147 (43%)
 Frame = +2

Query: 399 FDIYTAGAGTGDVAVVIVDPQGRRDTVEVALEDKGDNTFRCTYRPVMEGPHTVHVAFAGA 458
           F + T+ +G  +  V IV P G+  +V V + +     +  TY+P   G H + + +   
Sbjct: 77  FSVETSRSGKCEQTVRIVSPSGQ--SVPVDVTETSTYGYNITYQPSESGQHRIFLTYNSL 250

Query: 459 PITRSPFPVHVAEACNPNACRASGRGLQPKGVRVKEVADFKVFTKGAGSGELKVTVKGPK 518
            +  SPF   ++E   P    A G GL  +G   K  A F +  +G  +GE  V V GP 
Sbjct: 251 ELPGSPFTQEISEGVLPP---AYGEGLH-RGEEDK-AAIFYIDARGL-TGEPSVQVDGPN 412

Query: 519 GTEEPVKVREAGDGVFECEYYPVVPGK 545
              +   +    DG +   Y PV  G 
Sbjct: 413 SIAK-CSIEAQPDGQYSVTYIPVEVGS 490

 Score = 39.7 bits (91), Expect = 0.019,   Method: Compositional matrix adjust.
 Identities = 19/65 (29%), Positives = 33/65 (50%)
 Frame = +2

Query: 1667 ITVDAKAAGKGKVTCTVSTPDGAELDVDVVENHDGTFDIYYTAPEPGKYVITIRFGGEHI 1726
             +V+   +GK + T  + +P G  + VDV E     ++I Y   E G++ I + +    +
Sbjct: 77   FSVETSRSGKCEQTVRIVSPSGQSVPVDVTETSTYGYNITYQPSESGQHRIFLTYNSLEL 256

Query: 1727 PNSPF 1731
            P SPF
Sbjct: 257  PGSPF 271

 Score = 36.2 bits (82), Expect = 0.18,   Method: Compositional matrix adjust.
 Identities = 19/69 (27%), Positives = 31/69 (44%)
 Frame = +2

Query: 2657 FTVDCSKAGTNMMMVGVHGPKTPCEEVYVKHMGNRVYNVTYTVKEKGDYILIVKWGDESV 2716
            F+V+ S++G     V +  P      V V       YN+TY   E G + + + +    +
Sbjct: 77   FSVETSRSGKCEQTVRIVSPSGQSVPVDVTETSTYGYNITYQPSESGQHRIFLTYNSLEL 256

Query: 2717 PGSPFKVNV 2725
            PGSPF   +
Sbjct: 257  PGSPFTQEI 283

 Score = 34.3 bits (77), Expect = 0.67,   Method: Compositional matrix adjust.
 Identities = 18/77 (23%), Positives = 38/77 (49%), Gaps = 2/77 (2%)
 Frame = +2

Query: 1874 MVNKPATFTIVTKDAGEGGLSLAVEGPSKAEITCKDNKDGTC--TVSYLPTAPGDYSIIV 1931
            M+     F++ T  +G+   ++ +  PS   +     +  T    ++Y P+  G + I +
Sbjct: 56   MLANWLDFSVETSRSGKCEQTVRIVSPSGQSVPVDVTETSTYGYNITYQPSESGQHRIFL 235

Query: 1932 RFDDKHIPGSPFTAKIT 1948
             ++   +PGSPFT +I+
Sbjct: 236  TYNSLELPGSPFTQEIS 286

 Score = 34.3 bits (77), Expect = 0.74,   Method: Compositional matrix adjust.
 Identities = 21/71 (29%), Positives = 36/71 (50%), Gaps = 2/71 (2%)
 Frame = +2

Query: 2062 EFIVDTRNAGYGGLGLSIEGPSKVDINCEDMEDGTC--KVTYCPTEPGTYIINIKFADKH 2119
            +F V+T  +G     + I  PS   +  +  E  T    +TY P+E G + I + +    
Sbjct: 74   DFSVETSRSGKCEQTVRIVSPSGQSVPVDVTETSTYGYNITYQPSESGQHRIFLTYNSLE 253

Query: 2120 VPGSPFTVKVT 2130
            +PGSPFT +++
Sbjct: 254  LPGSPFTQEIS 286

 Score = 32.0 bits (71), Expect = 3.4,   Method: Compositional matrix adjust.
 Identities = 28/116 (24%), Positives = 51/116 (43%), Gaps = 4/116 (3%)
 Frame = +2

Query: 891  FTVLTKGAGKAKLDVHFAGAAKGEAVRDFEIIDNHDYSYTVKYTAVQQGNMAVTVTYGGD 950
            F+V T  +GK +  V    +  G++V   ++ +   Y Y + Y   + G   + +TY   
Sbjct: 77   FSVETSRSGKCEQTVRIV-SPSGQSV-PVDVTETSTYGYNITYQPSESGQHRIFLTYNSL 250

Query: 951  PVPKSPFVVNVA----PPLDLSKVKVQGLNSKVAVGQEQAFSVNTRGAGGQGQLDV 1002
             +P SPF   ++    PP     +  +G   K A+     F ++ RG  G+  + V
Sbjct: 251  ELPGSPFTQEISEGVLPPAYGEGLH-RGEEDKAAI-----FYIDARGLTGEPSVQV 400

 Score = 31.2 bits (69), Expect = 5.9,   Method: Compositional matrix adjust.
 Identities = 37/149 (24%), Positives = 61/149 (40%)
 Frame = +2

Query: 299 FTVQTVDAGVGEVLVYIEDPEGHTEEAKVVPNNDKDRTYAVSYVPKVAGLHKVTVLFAGQ 358
           F+V+T  +G  E  V I  P G +    V   +     Y ++Y P  +G H++ + +   
Sbjct: 77  FSVETSRSGKCEQTVRIVSPSGQSVPVDVTETSTYG--YNITYQPSESGQHRIFLTYNSL 250

Query: 359 NIERSPFEVNVGMALGDANKVSARGPGLEPVGNVANKPTYFDIYTAGAGTGDVAVVIVDP 418
            +  SPF       + +     A G GL       +K   F I   G  TG+ +V +   
Sbjct: 251 ELPGSPFT----QEISEGVLPPAYGEGLH--RGEEDKAAIFYIDARGL-TGEPSVQV--- 400

Query: 419 QGRRDTVEVALEDKGDNTFRCTYRPVMEG 447
            G     + ++E + D  +  TY PV  G
Sbjct: 401 DGPNSIAKCSIEAQPDGQYSVTYIPVEVG 487

 Score = 30.8 bits (68), Expect = 7.3,   Method: Compositional matrix adjust.
 Identities = 17/71 (23%), Positives = 33/71 (46%)
 Frame = +2

Query: 788 FTVDCSEAGQGDVSIGIKCAPGVVGPVEAXXXXXXXXXXXXTFTVKYTPPGAGHYTIMVL 847
           F+V+ S +G+ + ++ I    G   PV+              + + Y P  +G + I + 
Sbjct: 77  FSVETSRSGKCEQTVRIVSPSGQSVPVDVTETSTYG------YNITYQPSESGQHRIFLT 238

Query: 848 FANQEIPASPF 858
           + + E+P SPF
Sbjct: 239 YNSLELPGSPF 271
>35059
          Length = 669

 Score = 57.0 bits (136), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 50/178 (28%), Positives = 75/178 (42%)
 Frame = +2

Query: 1165 GLERGKAGEAATFTVDCSEAGEAELTIEILSDAGVKAEVLIQNNADGTYHITYSPAFPGT 1224
            G E  +A   A F VD   AG  E+ +E L    +   V I       Y  TY+PAFPG 
Sbjct: 107  GAEIARATVQAEFVVDGRRAGPGEVRVE-LKGVRISLPVHITPIKYDRYRCTYTPAFPGG 283

Query: 1225 YTITIKYGGHPIPKFPTRVHVQPAVDTSGIKVSGPGVEPHGVLREVTTEFTVDARSLTAT 1284
            + + + +    +P  P +V V    D S +KV+G G++  G +        VD +   + 
Sbjct: 284  FLLYVYWSNILVPGCPHKVTVTSKGDVSXVKVTGEGLK--GGIAGSELRVFVDNKRGWSR 457

Query: 1285 GGNHVTARVLNPSGAKTDTYVTDNGDGTYRVQYTAYEEGVHLVEVLYDEVAVPKSPFR 1342
            GGN   + + +     T     +     + V         HL++V YD   VP SP R
Sbjct: 458  GGN---SDMFDTPTRGTSGREAERLSPLHAVYPCPTSADKHLLQVRYDGQHVPGSPLR 622

 Score = 48.1 bits (113), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 30/100 (30%), Positives = 47/100 (47%)
 Frame = +2

Query: 689 AEFTIDARAAGKGDLKLYAQDADGCPIDIKVIPNGDGTFRCSYVPTKPIKHTIIVSWGGV 748
           AEF +D R AG G++++  +      + + + P     +RC+Y P  P    + V W  +
Sbjct: 137 AEFVVDGRRAGPGEVRVELKGVR-ISLPVHITPIKYDRYRCTYTPAFPGGFLLYVYWSNI 313

Query: 749 NVPKSPFRVNVGEGSHPERVKVYGPGVEKTGLKANEPTYF 788
            VP  P +V V        VKV G G+ K G+  +E   F
Sbjct: 314 LVPGCPHKVTVTSKGDVSXVKVTGEGL-KGGIAGSELRVF 430

 Score = 43.9 bits (102), Expect = 8e-04,   Method: Compositional matrix adjust.
 Identities = 34/123 (27%), Positives = 56/123 (45%), Gaps = 2/123 (1%)
 Frame = +2

Query: 2005 SFTPKEVGEHVVSVRKSGKHVTNSPFKILVGPSEIGDASKVRVWGKGLSEGQT-FQVAEF 2063
            ++TP   G  ++ V  S   V   P K+ V  +  GD S V+V G+GL  G    ++  F
Sbjct: 257  TYTPAFPGGFLLYVYWSNILVPGCPHKVTV--TSKGDVSXVKVTGEGLKGGIAGSELRVF 430

Query: 2064 IVDTRNAGYGGLGLSIEGPSKVDINCEDMEDGTCKVTY-CPTEPGTYIINIKFADKHVPG 2122
            + + R    GG     + P++     E          Y CPT    +++ +++  +HVPG
Sbjct: 431  VDNKRGWSRGGNSDMFDTPTRGTSGREAERLSPLHAVYPCPTSADKHLLQVRYDGQHVPG 610

Query: 2123 SPF 2125
            SP 
Sbjct: 611  SPL 619

 Score = 43.1 bits (100), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 34/128 (26%), Positives = 55/128 (42%), Gaps = 6/128 (4%)
 Frame = +2

Query: 1121 SYLPTEPGEYTINILFAEAHIPGSPFKATIQPVFDPSKVRASGPGLERGKAGEAATFTVD 1180
            +Y P  PG + + + ++   +PG P K T+    D S V+ +G GL+ G AG      VD
Sbjct: 257  TYTPAFPGGFLLYVYWSNILVPGCPHKVTVTSKGDVSXVKVTGEGLKGGIAGSELRVFVD 436

Query: 1181 ----CSEAGEAEL-TIEILSDAGVKAEVLIQNNADGTYHITY-SPAFPGTYTITIKYGGH 1234
                 S  G +++        +G +AE L         H  Y  P     + + ++Y G 
Sbjct: 437  NKRGWSRGGNSDMFDTPTRGTSGREAERL------SPLHAVYPCPTSADKHLLQVRYDGQ 598

Query: 1235 PIPKFPTR 1242
             +P  P R
Sbjct: 599  HVPGSPLR 622

 Score = 42.7 bits (99), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 52/181 (28%), Positives = 70/181 (38%), Gaps = 9/181 (4%)
 Frame = +2

Query: 882  GVEVGKPT---HFTVLTKGAGKAKLDVHFAGAAKGEAVRDFEIIDNHDYSYTVKYTAVQQ 938
            G E+ + T    F V  + AG  ++ V   G      V    I   +D  Y   YT    
Sbjct: 107  GAEIARATVQAEFVVDGRRAGPGEVRVELKGVRISLPVHITPI--KYD-RYRCTYTPAFP 277

Query: 939  GNMAVTVTYGGDPVPKSPFVVNVAPPLDLSKVKV--QGLNSKVAVGQEQAFSVNTRGAGG 996
            G   + V +    VP  P  V V    D+S VKV  +GL   +A  + + F  N RG   
Sbjct: 278  GGFLLYVYWSNILVPGCPHKVTVTSKGDVSXVKVTGEGLKGGIAGSELRVFVDNKRGWSR 457

Query: 997  QGQLDVRMTSPSRRPIPCKLEPGGGAE----AQAVRYMPPEEGPYKVDITYDGHPVPGSP 1052
             G  D+  T       P +   G  AE      AV   P     + + + YDG  VPGSP
Sbjct: 458  GGNSDMFDT-------PTRGTSGREAERLSPLHAVYPCPTSADKHLLQVRYDGQHVPGSP 616

Query: 1053 F 1053
             
Sbjct: 617  L 619

 Score = 42.4 bits (98), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 25/85 (29%), Positives = 45/85 (52%), Gaps = 1/85 (1%)
 Frame = +2

Query: 2050 KGLSEGQTFQVAEFIVDTRNAGYGGLGLSIEGPS-KVDINCEDMEDGTCKVTYCPTEPGT 2108
            KG    +    AEF+VD R AG G + + ++G    + ++   ++    + TY P  PG 
Sbjct: 104  KGAEIARATVQAEFVVDGRRAGPGEVRVELKGVRISLPVHITPIKYDRYRCTYTPAFPGG 283

Query: 2109 YIINIKFADKHVPGSPFTVKVTGEG 2133
            +++ + +++  VPG P  V VT +G
Sbjct: 284  FLLYVYWSNILVPGCPHKVTVTSKG 358

 Score = 39.3 bits (90), Expect = 0.024,   Method: Compositional matrix adjust.
 Identities = 41/173 (23%), Positives = 69/173 (39%), Gaps = 2/173 (1%)
 Frame = +2

Query: 2324 GLERGVAGVPAEFSIWTREAGAGGLSIAVEGPS-KAEIAFEDRKDGSCGVSYVVQEPGDY 2382
            G E   A V AEF +  R AG G + + ++G      +     K      +Y    PG +
Sbjct: 107  GAEIARATVQAEFVVDGRRAGPGEVRVELKGVRISLPVHITPIKYDRYRCTYTPAFPGGF 286

Query: 2383 EVSIKFNDEHIPDSPFVVPVASLSDDARRLTVTSLQETGLKVNQPASFAVQLNG-ARGVI 2441
             + + +++  +P  P  V V S  D +         + G+  ++   F     G +RG  
Sbjct: 287  LLYVYWSNILVPGCPHKVTVTSKGDVSXVKVTGEGLKGGIAGSELRVFVDNKRGWSRGGN 466

Query: 2442 DARVHTPSGAVEECYVSELDSDKHTIRFIPHENGVHSIDVKFNGAHIPGSPFK 2494
                 TP+          L S  H +   P     H + V+++G H+PGSP +
Sbjct: 467  SDMFDTPTRGTSGREAERL-SPLHAVYPCPTSADKHLLQVRYDGQHVPGSPLR 622

 Score = 38.1 bits (87), Expect = 0.049,   Method: Compositional matrix adjust.
 Identities = 37/162 (22%), Positives = 70/162 (43%), Gaps = 4/162 (2%)
 Frame = +2

Query: 406 AGTGDVAVVIVDPQGRRDTVEVALEDKGDNTFRCTYRPVMEGPHTVHVAFAGAPITRSPF 465
           AG G+V V +   +G R ++ V +     + +RCTY P   G   ++V ++   +   P 
Sbjct: 164 AGPGEVRVEL---KGVRISLPVHITPIKYDRYRCTYTPAFPGGFLLYVYWSNILVPGCPH 334

Query: 466 PVHVAEACNPNACRASGRGLQPKGVRVKEVADF----KVFTKGAGSGELKVTVKGPKGTE 521
            V V    + +  + +G GL+  G+   E+  F    + +++G  S       +G  G E
Sbjct: 335 KVTVTSKGDVSXVKVTGEGLK-GGIAGSELRVFVDNKRGWSRGGNSDMFDTPTRGTSGRE 511

Query: 522 EPVKVREAGDGVFECEYYPVVPGKYVVTITWGGYAIPRSPFE 563
              +       V+ C   P    K+++ + + G  +P SP  
Sbjct: 512 --AERLSPLHAVYPC---PTSADKHLLQVRYDGQHVPGSPLR 622

 Score = 36.2 bits (82), Expect = 0.20,   Method: Compositional matrix adjust.
 Identities = 26/84 (30%), Positives = 41/84 (48%)
 Frame = +2

Query: 2642 RGPGLSQAFVGQKNSFTVDCSKAGTNMMMVGVHGPKTPCEEVYVKHMGNRVYNVTYTVKE 2701
            +G  +++A V  +  F VD  +AG   + V + G +     V++  +    Y  TYT   
Sbjct: 104  KGAEIARATV--QAEFVVDGRRAGPGEVRVELKGVRISLP-VHITPIKYDRYRCTYTPAF 274

Query: 2702 KGDYILIVKWGDESVPGSPFKVNV 2725
             G ++L V W +  VPG P KV V
Sbjct: 275  PGGFLLYVYWSNILVPGCPHKVTV 346

 Score = 35.4 bits (80), Expect = 0.31,   Method: Compositional matrix adjust.
 Identities = 30/100 (30%), Positives = 45/100 (45%), Gaps = 13/100 (13%)
 Frame = +2

Query: 2515 GLEGGTTGVSSEFIVNTQNAGSGALSVTIDGPSKVQLDCRECP---EGHVVTYTPMAPGN 2571
            G E     V +EF+V+ + AG G + V + G  ++ L     P   + +  TYTP  PG 
Sbjct: 107  GAEIARATVQAEFVVDGRRAGPGEVRVELKG-VRISLPVHITPIKYDRYRCTYTPAFPGG 283

Query: 2572 YLIAIKY------GGPQHIV----GSPFKAKVTGPRLSGG 2601
            +L+ + +      G P  +     G     KVTG  L GG
Sbjct: 284  FLLYVYWSNILVPGCPHKVTVTSKGDVSXVKVTGEGLKGG 403

 Score = 33.9 bits (76), Expect = 0.94,   Method: Compositional matrix adjust.
 Identities = 42/170 (24%), Positives = 65/170 (38%), Gaps = 17/170 (10%)
 Frame = +2

Query: 1879 ATFTIVTKDAGEGGLSLAVEGPSKA---EITCKDNKDGTCTVSYLPTAPGDYSIIVRFDD 1935
            A F +  + AG G + + ++G   +    IT        CT  Y P  PG + + V + +
Sbjct: 137  AEFVVDGRRAGPGEVRVELKGVRISLPVHITPIKYDRYRCT--YTPAFPGGFLLYVYWSN 310

Query: 1936 KHIPGSPFTAKIT--GDDS------------MRTSQLNVGTSTDVSLKITEGDLSQLTAS 1981
              +PG P    +T  GD S            +  S+L V            G+       
Sbjct: 311  ILVPGCPHKVTVTSKGDVSXVKVTGEGLKGGIAGSELRVFVDNKRGWS-RGGNSDMFDTP 487

Query: 1982 IRAPSGNEEPCLLKRLPNRHIGISFTPKEVGEHVVSVRKSGKHVTNSPFK 2031
             R  SG E     +RL   H  +   P    +H++ VR  G+HV  SP +
Sbjct: 488  TRGTSGREA----ERLSPLH-AVYPCPTSADKHLLQVRYDGQHVPGSPLR 622

 Score = 33.9 bits (76), Expect = 1.0,   Method: Compositional matrix adjust.
 Identities = 12/25 (48%), Positives = 17/25 (68%)
 Frame = +2

Query: 1828 APTEKGLHQMGIKYDGNHIPGSPLQ 1852
             PT    H + ++YDG H+PGSPL+
Sbjct: 548  CPTSADKHLLQVRYDGQHVPGSPLR 622

 Score = 33.5 bits (75), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 43/174 (24%), Positives = 70/174 (40%), Gaps = 3/174 (1%)
 Frame = +2

Query: 977  SKVAVGQEQA-FSVNTRGAGGQGQLDVRMTSPSRRPIPCKLEPGGGAEAQAVRYMPPEEG 1035
            +++A    QA F V+ R AG  G++ V +    R  +P  + P      +   Y P   G
Sbjct: 110  AEIARATVQAEFVVDGRRAG-PGEVRVELKG-VRISLPVHITPIKYDRYRCT-YTPAFPG 280

Query: 1036 PYKVDITYDGHPVPGSPFAVEGVLPPDPSKVCAYGPGLKGGLVGTPAPFSIDTKXXXXXX 1095
             + + + +    VPG P  V      D S V   G GLKGG+ G+     +D K      
Sbjct: 281  GFLLYVYWSNILVPGCPHKVTVTSKGDVSXVKVTGEGLKGGIAGSELRVFVDNKRGWSRG 460

Query: 1096 XXXXVEGPCEAKIECQDNGDGS--CAVSYLPTEPGEYTINILFAEAHIPGSPFK 1147
                +          ++    S   AV   PT   ++ + + +   H+PGSP +
Sbjct: 461  GNSDMFDTPTRGTSGREAERLSPLHAVYPCPTSADKHLLQVRYDGQHVPGSPLR 622

 Score = 31.6 bits (70), Expect = 4.6,   Method: Compositional matrix adjust.
 Identities = 31/133 (23%), Positives = 54/133 (40%), Gaps = 3/133 (2%)
 Frame = +2

Query: 1814 NITDNKDGTITVRYAPTEKGLHQMGIKYDGNHIPGSPLQFYVDAI-NSRHVSAYGPGLSH 1872
            +IT  K       Y P   G   + + +    +PG P +  V +  +   V   G GL  
Sbjct: 221  HITPIKYDRYRCTYTPAFPGGFLLYVYWSNILVPGCPHKVTVTSKGDVSXVKVTGEGLKG 400

Query: 1873 GMV-NKPATFTIVTKDAGEGGLSLAVEGPSKAEITCKDNKDGTCTVSY-LPTAPGDYSII 1930
            G+  ++   F    +    GG S   + P++     +  +       Y  PT+   + + 
Sbjct: 401  GIAGSELRVFVDNKRGWSRGGNSDMFDTPTRGTSGREAERLSPLHAVYPCPTSADKHLLQ 580

Query: 1931 VRFDDKHIPGSPF 1943
            VR+D +H+PGSP 
Sbjct: 581  VRYDGQHVPGSPL 619

 Score = 30.4 bits (67), Expect = 9.3,   Method: Compositional matrix adjust.
 Identities = 13/30 (43%), Positives = 18/30 (60%)
 Frame = +2

Query: 2275 YSVRFVPQEMGPHTVTVKYRGQHVPGSPFQ 2304
            ++V   P     H + V+Y GQHVPGSP +
Sbjct: 533  HAVYPCPTSADKHLLQVRYDGQHVPGSPLR 622
>09100
          Length = 930

 Score = 53.1 bits (126), Expect = 2e-06,   Method: Composition-based stats.
 Identities = 34/116 (29%), Positives = 60/116 (51%), Gaps = 4/116 (3%)
 Frame = +1

Query: 31  EDAPWKKIQQ--NTFTRWCNEHLKCV--GKRLTDLQRDLSDGLRLIALLEVLSQKRMYRK 86
           E   W + QQ  + +  W N  LK       + DL+ D+ DG+    ++ ++S++++   
Sbjct: 433 ESRTWIEPQQQLSAYMAWINSQLKKKPGAHLIEDLRHDMRDGVVFADVIHIVSKQQIPGI 612

Query: 87  FHPRPNFRQMKLENVSVALEFLEREHIKLVSIDSKAIVDGNLKLILGLIWTLILHY 142
            +      +M+ +NV   L F+ +  IK+  I S+ IV+GNLK ++ LI  L  HY
Sbjct: 613 QNVPTTLDEMR-QNVDRVLHFMTQNRIKMHRISSRDIVEGNLKAVMRLILALAAHY 777
>17613
          Length = 1108

 Score = 52.8 bits (125), Expect = 2e-06,   Method: Composition-based stats.
 Identities = 27/61 (44%), Positives = 38/61 (62%)
 Frame = +2

Query: 113 IKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWEDEDDEDARKQTPKQRLLGWIQN 172
           +KLVSI ++ IVDGN+K+ LG+IWT+IL ++I         D    + T K+ LL W Q 
Sbjct: 65  VKLVSIGAEEIVDGNVKMTLGMIWTIILRFAIQ--------DITVEELTAKEGLLLWCQR 220

Query: 173 K 173
           K
Sbjct: 221 K 223
>04951
          Length = 2852

 Score = 49.7 bits (117), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 46/157 (29%), Positives = 79/157 (50%), Gaps = 10/157 (6%)
 Frame = +1

Query: 97  KLENVSVALEF---LEREHIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWEDED 153
           K+EN   A++    ++   +KLV I  K I DGN  L LGL+W L+  Y++++     ED
Sbjct: 4   KIENCEYAVQLGPQMKVCKMKLVGIGGKDIHDGNPVLTLGLVWQLMRAYTLAILSKLTED 183

Query: 154 DEDARKQTPKQRLLGWIQNKVPQ-LPITNF-NRDWQDGKALGALVDNCAPGLCPDWEAWD 211
               +K      ++ W+ +KV +   I +F +    DG  +  ++++  PG+  +WE  +
Sbjct: 184 ----KKPIQDSEIVDWVNSKVKKDERIGSFQDSKLNDGVIVAKVIESIKPGIV-NWENIN 348

Query: 212 PNQP-----VQNAREAMQQADDWLGVPQVIAPEEIVD 243
           PN       + NAR A+  A   +G      PE+IV+
Sbjct: 349 PNASEPDDRLANARYAIGLARK-IGAGVYALPEDIVE 456
>09711
          Length = 3041

 Score = 48.9 bits (115), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 57/219 (26%), Positives = 102/219 (46%), Gaps = 14/219 (6%)
 Frame = +1

Query: 39   QQNTFTRWCNEHLKCVGKRLTDLQRDLSDGLRLIALLEV----LSQKRMYRKFHPRPNFR 94
            ++ T+  W N     V   +  L  DL DGL +  L +     L      +K   +   R
Sbjct: 850  EEKTYRNWMNS--LGVSPFVHHLYSDLYDGLIIFQLYDYIQPGLVDWSKVKKKFNKLKAR 1023

Query: 95   QMKLENVSVALEF---LEREHIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWED 151
              ++EN + A+E    ++   +KLV I  + I+DGN  L LGL+W L+  Y++++     
Sbjct: 1024 FERIENCNYAVELGPQVKLVKVKLVGIAGQDILDGNPVLTLGLVWQLMRAYTLAILSKIT 1203

Query: 152  EDDEDARKQTPKQRLLGWIQNKVPQLP-ITNF-NRDWQDGKALGALVDNCAPGLCPDWE- 208
            E++    K      ++ W+ +K+ +   I+ F +R   DG  +  +++   PG+  +W+ 
Sbjct: 1204 ENN----KPISDNEIITWVNSKIKKDDRISGFQDRKLNDGVIVARVIEAIKPGIV-NWDN 1368

Query: 209  ----AWDPNQPVQNAREAMQQADDWLGVPQVIAPEEIVD 243
                A D    + NAR A+  A   +G      PE+IV+
Sbjct: 1369 IDCSARDYQDRLTNARYAIGLARK-IGAGVYALPEDIVE 1482

 Score = 40.0 bits (92), Expect = 0.012,   Method: Compositional matrix adjust.
 Identities = 46/190 (24%), Positives = 79/190 (41%), Gaps = 27/190 (14%)
 Frame = +1

Query: 39  QQNTFTRWCNEHLK----CVGKRLTDLQRD-------LSDGLRLIALLEVLSQKRMYRKF 87
           +Q  F  W N HL     C  K L  L  D       ++DG+ L  L+       +  + 
Sbjct: 52  EQKAFAEWINRHLSDXPDC--KHLLPLDADGTQLFGQMADGVLLCKLINHSVSNTIDERT 225

Query: 88  HPRPNFRQMKL-ENVSVALEFLEREHIKLVSIDSKAIVDGNLKLILGLIWTLI---LHYS 143
             + N    +  EN+++A+          V+I  + +  G   L+LGL+W +I   L   
Sbjct: 226 INKQNLSLYRRHENLTLAVNSAGAIGCTTVNIGPEDLAAGRPHLVLGLLWQIIRIGLLSD 405

Query: 144 ISMP--------MWEDEDDEDARKQTPKQRLLGWIQNKVPQL----PITNFNRDWQDGKA 191
           I++         + + E  ED  + +P+Q LL W+   + +      I NF  D +D +A
Sbjct: 406 INLAHHPGLVNLLLDGETIEDLIRLSPEQILLRWVNYHLNRAGCDRQIXNFGEDIKDSEA 585

Query: 192 LGALVDNCAP 201
              L+   +P
Sbjct: 586 YTHLLKQISP 615
>32088
          Length = 1928

 Score = 39.7 bits (91), Expect = 0.015,   Method: Composition-based stats.
 Identities = 38/156 (24%), Positives = 65/156 (41%), Gaps = 21/156 (13%)
 Frame = +1

Query: 36   KKIQQNTFTRWCNEHLK----C-----VGKRLTDLQRDLSDGLRLIALLEVLSQKRMYRK 86
            K  +Q  F  W N HLK    C     V +   DL + + DG+ L  L+       +  +
Sbjct: 1255 KDGEQKAFAAWINRHLKDDPDCKHLMEVNEEGDDLFKKVGDGILLCKLINHSVSNTIDER 1434

Query: 87   FHPRPNFR-QMKLENVSVALEFLEREHIKLVSIDSKAIVDGNLKLILGLIWTLIL----- 140
               + N     + EN+++A+          V+I  + +  G   L+LGL+W +I      
Sbjct: 1435 AINKSNLNVYHRHENLTLAVNSAGSIGCTTVNIGPEDLAAGRPHLVLGLLWQIIRIGLLS 1614

Query: 141  ------HYSISMPMWEDEDDEDARKQTPKQRLLGWI 170
                  H  +   + E E  ED  + +P++ LL W+
Sbjct: 1615 DINLAHHPGLVNLLREGETIEDFMRLSPEEILLRWV 1722
>18202
          Length = 424

 Score = 34.3 bits (77), Expect = 0.64,   Method: Composition-based stats.
 Identities = 16/44 (36%), Positives = 30/44 (68%)
 Frame = -1

Query: 101 VSVALEFLEREHIKLVSIDSKAIVDGNLKLILGLIWTLILHYSI 144
           +  AL+ ++   IK+V   ++ I+DG++K +L ++W LIL+Y I
Sbjct: 211 IYAALDHMKNHGIKIV-FSTQDIMDGDIKSLLDVMWLLILNYGI 83
>02928
          Length = 1057

 Score = 34.3 bits (77), Expect = 0.70,   Method: Compositional matrix adjust.
 Identities = 20/61 (32%), Positives = 30/61 (49%)
 Frame = +3

Query: 729 CSYVPTKPIKHTIIVSWGGVNVPKSPFRVNVGEGSHPERVKVYGPGVEKTGLKANEPTYF 788
           C  VP +P +  +  S G     +SP  V      HP R+++  P V K G++  E +YF
Sbjct: 486 CQLVPAEPPEQPVCRSLGAQRH-QSPACV------HPPRLRLSDPAVHKAGVQGQEASYF 644

Query: 789 T 789
           T
Sbjct: 645 T 647
>31031
          Length = 423

 Score = 31.6 bits (70), Expect = 4.5,   Method: Compositional matrix adjust.
 Identities = 26/94 (27%), Positives = 42/94 (44%), Gaps = 13/94 (13%)
 Frame = +1

Query: 2048 WGKGLSEGQTFQVAEFI---VDTR------NAGYGGLGLSIEGPS---KVDINCEDMEDG 2095
            WG GL       V  F    VDT+      + G G   +S+       ++ ++  D  DG
Sbjct: 19   WGPGLKSHFNVPVRYFYIQAVDTKGNHLTDSVGEGAFQVSVTQNGQRVRMRVDVLDRHDG 198

Query: 2096 TCKVTYCP-TEPGTYIINIKFADKHVPGSPFTVK 2128
               V   P ++P   +++IK  D+HV  SP+ +K
Sbjct: 199  VYIVRLKPFSDPEHIVVSIKHNDQHVAHSPYQIK 300

 Score = 30.8 bits (68), Expect = 8.4,   Method: Compositional matrix adjust.
 Identities = 17/64 (26%), Positives = 35/64 (54%), Gaps = 3/64 (4%)
 Frame = +1

Query: 1673 AAGKGKVTCTVSTPDG--AELDVDVVENHDGTFDIYYT-APEPGKYVITIRFGGEHIPNS 1729
            + G+G    +V T +G    + VDV++ HDG + +      +P   V++I+   +H+ +S
Sbjct: 109  SVGEGAFQVSV-TQNGQRVRMRVDVLDRHDGVYIVRLKPFSDPEHIVVSIKHNDQHVAHS 285

Query: 1730 PFHV 1733
            P+ +
Sbjct: 286  PYQI 297
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|84490394|ref|NP_038703.3| spectrin beta 1 [Mus
musculus]
         (2329 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

19002                                                                 426   e-119
34010                                                                 136   2e-39
26578                                                                 150   6e-36
17613                                                                  97   1e-35
19147                                                                 121   3e-28
29446                                                                  92   2e-18
05733                                                                  82   3e-15
34417                                                                  81   4e-15
28965                                                                  80   9e-15
38533                                                                  67   1e-10
19246                                                                  62   3e-09
09100                                                                  56   2e-07
09711                                                                  54   6e-07
25051                                                                  52   4e-06
22703                                                                  51   6e-06
11159                                                                  49   2e-05
17567                                                                  49   2e-05
32371                                                                  37   2e-05
18202                                                                  46   2e-04
32088                                                                  43   0.002
18556                                                                  42   0.003
19732                                                                  40   0.013
04951                                                                  39   0.019
22686                                                                  35   0.35 
29521                                                                  33   1.5  
>19002
          Length = 842

 Score =  426 bits (1096), Expect = e-119,   Method: Compositional matrix adjust.
 Identities = 201/280 (71%), Positives = 234/280 (83%)
 Frame = -2

Query: 84  DGRMLIKLLEVLSGEMLPRPTKGKMRIHCLENVDKALQFLKEQRVHLENMGSHDIVDGNH 143
           DG+ML+KLLEV     +    KGKMRIHCLENVDKAL FL EQRVHLENMG+HDIVDG+ 
Sbjct: 841 DGKMLMKLLEVRVRGEIASDXKGKMRIHCLENVDKALTFLHEQRVHLENMGAHDIVDGSS 662

Query: 144 RLVLGLIWTIILRFQIQDIVVQTQEGRETRSAKDALLLWCQMKTAGYPHVNVTNFTSSWK 203
           RL LGLIWTIILRFQIQDI+++  +  ET+SAKDALLLWCQMKTAGYP+VNV NFT+SW+
Sbjct: 661 RLTLGLIWTIILRFQIQDIMIEEVDNSETKSAKDALLLWCQMKTAGYPNVNVRNFTTSWR 482

Query: 204 DGLAFNALIHKHRPDLIDFDKLKDSNARHNLEHAFDVAERQLGIIPLLDPEDVFTENPDE 263
           DGLAFNA+IHKHRPDL+ +D+L  S+A  NL++AF VAE +LG+  LL+PEDV  E PDE
Sbjct: 481 DGLAFNAIIHKHRPDLVQYDRLHKSSAIQNLQNAFTVAEDKLGLTALLEPEDVNVEYPDE 302

Query: 264 KSIITYVVAFYHYFSKMKVLAVEGKRVGKVIDHAIETEKMIEKYSGLASDLLTWIEQTIS 323
           KSIITYVV +YHYFSKMK  +V+GKR+GKVID+AI TE  IE+Y  L SDLL WIEQTI 
Sbjct: 301 KSIITYVVTYYHYFSKMKADSVQGKRIGKVIDNAINTENSIEEYETLTSDLLEWIEQTIV 122

Query: 324 VLNSRKFANSLSGVQQQLQAFSTYRTVEKPPKFQEKGNLE 363
           +L  R+FANSL+GVQQQL AF+TYR VEKPPKF EKGNLE
Sbjct: 121 ILRDRQFANSLTGVQQQLAAFNTYRIVEKPPKFDEKGNLE 2
>34010
          Length = 832

 Score =  136 bits (342), Expect(3) = 2e-39,   Method: Compositional matrix adjust.
 Identities = 68/140 (48%), Positives = 93/140 (66%)
 Frame = +3

Query: 1931 RPRDVSSVELLLKYHQGIKAEINTRAKNFSTCLELGESLLQRQHQASDEIREKLQQVISR 1990
            +PRDVS VELL+  HQ +KAEI+ R +NF+ C+ LG  LL R+H   +E+REKL Q+   
Sbjct: 84   KPRDVSGVELLMNNHQSLKAEIDAREENFAICINLGRDLLNRKHYRQEEVREKLIQLTLE 263

Query: 1991 RQEMNDKWEARSDRLHMLLEVCQFSRDASVAEAWLIAQEPYLASRDFGHTVDSVEKLIKR 2050
            R +M D W+ R + L ++LEV QF+RDA+VAEAWL+AQE Y  ++D G T+D+VE LIK 
Sbjct: 264  RLDMTDLWKDRWEHLQLILEVYQFARDAAVAEAWLVAQEQYFLNQDLGDTLDAVENLIKS 443

Query: 2051 HEAFEKSTASWAERFAALEK 2070
             +   KS      +   L K
Sbjct: 444  MKPL-KSCCHARRKICCLRK 500

 Score = 36.6 bits (83), Expect(3) = 2e-39,   Method: Composition-based stats.
 Identities = 16/30 (53%), Positives = 20/30 (66%)
 Frame = +1

Query: 1903 ADKFRFFSMVRDLLSWMESIIRQIETQERP 1932
            +D +RF  M  DL  WM+ IIRQ+ TQE P
Sbjct: 1    SDFYRFMLMAHDLHLWMDDIIRQMNTQENP 90

 Score = 31.2 bits (69), Expect(3) = 2e-39,   Method: Compositional matrix adjust.
 Identities = 13/15 (86%), Positives = 14/15 (93%)
 Frame = +1

Query: 2063 ERFAALEKPTTLELK 2077
            ERFAALEKPTT E+K
Sbjct: 478  ERFAALEKPTTFEIK 522

 Score = 36.6 bits (83), Expect = 0.12,   Method: Compositional matrix adjust.
 Identities = 39/141 (27%), Positives = 62/141 (43%), Gaps = 4/141 (2%)
 Frame = +3

Query: 1090 PESLPEAEQLLQQHAAIKEEIDAHRDDYHRVKASGEKVIEG----QTDPDYQLLGQRLEG 1145
            P  +   E L+  H ++K EIDA  +++      G  ++      Q +   +L+   LE 
Sbjct: 87   PRDVSGVELLMNNHQSLKAEIDAREENFAICINLGRDLLNRKHYRQEEVREKLIQLTLER 266

Query: 1146 LDTDWDALRRMWESRGNTLTQCLGFQEFQKDAKQAEAILSNQEYTLAHLEPPDSLAAAEA 1205
            LD     +  +W+ R   L   L   +F +DA  AEA L  QE    + +  D+L A E 
Sbjct: 267  LD-----MTDLWKDRWEHLQLILEVYQFARDAAVAEAWLVAQEQYFLNQDLGDTLDAVEN 431

Query: 1206 GIRKFEDFLVSMENNRDKILS 1226
             I+  +  L S  + R KI  
Sbjct: 432  LIKSMKP-LKSCCHARRKICC 491
>26578
          Length = 430

 Score =  150 bits (379), Expect = 6e-36,   Method: Compositional matrix adjust.
 Identities = 70/133 (52%), Positives = 101/133 (75%)
 Frame = +1

Query: 1681 ERRRRLENMYHLFQLKREADDLEQWITEKEMVASSQEMGQDFDHVTMLRDKFRDFARETG 1740
            ERR +LE ++ L+ L RE  DL QWI EK +VA S + GQD++HV+ML+++F++FAR+T 
Sbjct: 1    ERRGKLEEVFKLYTLHREIYDLLQWIAEKSLVAGSNDPGQDYEHVSMLKEQFKEFARDTE 180

Query: 1741 AIGQERVDNVNTIIERLIDAGHSEAATIAEWKDGLNDMWADLLELIDTRMQLLAASYDLH 1800
            ++GQERV + N I ++LI   HS++A+IAEWKD +N+ WADLLELIDTR QLL +S++LH
Sbjct: 181  SMGQERVASANEICDQLIALDHSDSASIAEWKDNVNEAWADLLELIDTRTQLLQSSWELH 360

Query: 1801 RYFYTGTEILGLI 1813
            ++ Y   + L  I
Sbjct: 361  KFLYECKDTLERI 399

 Score = 31.2 bits (69), Expect = 4.8,   Method: Compositional matrix adjust.
 Identities = 30/127 (23%), Positives = 53/127 (41%), Gaps = 1/127 (0%)
 Frame = +1

Query: 629 RKAQLEQSKRLWKFFWEMDEAESWIKEKEQIYSSLDYGKDLTSVLILQRKHKAFEDELRG 688
           R+ +LE+  +L+    E+ +   WI EK  +  S D G+D   V +L+ + K F  +   
Sbjct: 4   RRGKLEEVFKLYTLHREIYDLLQWIAEKSLVAGSNDPGQDYEHVSMLKEQFKEFARDTES 183

Query: 689 L-DAHLKQIFQEADDMVAQKQFGHPQIETRVKEVSAQWDHLKELAAFRKKDLQDAENFFQ 747
           +    +    +  D ++A        I      V+  W  L EL   R + LQ +    +
Sbjct: 184 MGQERVASANEICDQLIALDHSDSASIAEWKDNVNEAWADLLELIDTRTQLLQSSWELHK 363

Query: 748 FQGDADD 754
           F  +  D
Sbjct: 364 FLYECKD 384
>17613
          Length = 1108

 Score = 96.7 bits (239), Expect(2) = 1e-35,   Method: Compositional matrix adjust.
 Identities = 49/132 (37%), Positives = 75/132 (56%), Gaps = 1/132 (0%)
 Frame = +3

Query: 235 EHAFDVAERQLGIIPLLDPED-VFTENPDEKSIITYVVAFYHYFSKMKVLAVEGKRVGKV 293
           +H F    + L I  +LDPED V +  PDE+S++ YV ++YH FS  +       R+ KV
Sbjct: 366 QHCF*HRRKHLDIPRMLDPEDMVNSAKPDERSVMAYVSSYYHAFSGAQQAETAANRICKV 545

Query: 294 IDHAIETEKMIEKYSGLASDLLTWIEQTISVLNSRKFANSLSGVQQQLQAFSTYRTVEKP 353
           +    E E+++E+Y  LASDLL WI +T   L +R   N+L G + +L  F  YR  +KP
Sbjct: 546 LKVNQENERLMEEYERLASDLLEWIRRTRPWLENRVTDNTLPGTRHKLDEFRDYRRKQKP 725

Query: 354 PKFQEKGNLEVL 365
           P ++ + +   L
Sbjct: 726 PSWRTRPSWRTL 761

 Score = 74.3 bits (181), Expect(2) = 1e-35,   Method: Composition-based stats.
 Identities = 52/138 (37%), Positives = 70/138 (50%), Gaps = 3/138 (2%)
 Frame = +1

Query: 108 MRIHCLENVDKALQFLKEQRVHLENMGSHDIVDGNHRLVLGLIWTIILRFQIQD---IVV 164
           MR H + NV+KAL ++  QR      G H       R     I     R+ + +   +  
Sbjct: 4   MRFHKIANVNKALDYIDLQR---GQTGLHRSRRNC*RQRKDDI-----RYDLDNYPQVCH 159

Query: 165 QTQEGRETRSAKDALLLWCQMKTAGYPHVNVTNFTSSWKDGLAFNALIHKHRPDLIDFDK 224
                R T   +  +++    KTA Y +VNV NF  S+KDGLAF ALIH+HRP+LID+  
Sbjct: 160 PRHHSRRTHCQRRTVIV-VPAKTAPYKNVNVQNFHLSFKDGLAFCALIHRHRPELIDYHS 336

Query: 225 LKDSNARHNLEHAFDVAE 242
           L   N   NL  AFD+AE
Sbjct: 337 LSKDNPLENLNTAFDIAE 390

 Score = 74.7 bits (182), Expect = 4e-13,   Method: Compositional matrix adjust.
 Identities = 45/126 (35%), Positives = 68/126 (53%), Gaps = 1/126 (0%)
 Frame = +2

Query: 354 PKFQEKGNLEVLLFTIQSRMRANNQKVYTPHDGKLVSDINRAWESLEEAEYQRELALRSE 413
           PK ++K  LE    T+Q+R+R +N+  Y P +GK+VSDI  AW+ LE AE   E  L SE
Sbjct: 725 PKLEDKAKLENSFNTLQTRLRLSNRPAYLPTEGKMVSDIANAWKGLEHAEKGFEEWLLSE 904

Query: 414 LIRQEKLEQLARRFDRKAAMRETWLNENQRLVTQDNFG-YDLXXXXXXXXXXXXXXTDTA 472
           L R E+L+ LA++F  K  + E W    + ++   +F    L              +D A
Sbjct: 905 LQRLERLDHLAQKFRHKCEIHEEWSQGKEDMLQSRDFKQCRLNELKAMKKKHEAFESDLA 1084

Query: 473 AYEERV 478
           A+++RV
Sbjct: 1085AHQDRV 1102

 Score = 32.0 bits (71), Expect = 3.1,   Method: Compositional matrix adjust.
 Identities = 17/53 (32%), Positives = 28/53 (52%), Gaps = 1/53 (1%)
 Frame = +2

Query: 2013 QFSRDASVAEAWLIAQEPYLASRDFGHT-VDSVEKLIKRHEAFEKSTASWAER 2064
            +F     + E W   +E  L SRDF    ++ ++ + K+HEAFE   A+  +R
Sbjct: 941  KFRHKCEIHEEWSQGKEDMLQSRDFKQCRLNELKAMKKKHEAFESDLAAHQDR 1099
>19147
          Length = 474

 Score =  121 bits (303), Expect(2) = 3e-28,   Method: Compositional matrix adjust.
 Identities = 59/105 (56%), Positives = 76/105 (72%)
 Frame = +1

Query: 121 QFLKEQRVHLENMGSHDIVDGNHRLVLGLIWTIILRFQIQDIVVQTQEGRETRSAKDALL 180
            ++  + V L ++G+ +IVDGN ++ LG+IWTIILRF IQDI V      E  +AK+ LL
Sbjct: 46  SYIASKGVKLVSIGAEEIVDGNVKMTLGMIWTIILRFAIQDITV------EELTAKEGLL 207

Query: 181 LWCQMKTAGYPHVNVTNFTSSWKDGLAFNALIHKHRPDLIDFDKL 225
           LWCQ KTA Y +VNV NF  S+KDGLAF ALIH+HRP+LID+  L
Sbjct: 208 LWCQRKTAPYKNVNVQNFHLSFKDGLAFCALIHRHRPELIDYHSL 342

 Score = 24.6 bits (52), Expect(2) = 3e-28,   Method: Compositional matrix adjust.
 Identities = 11/21 (52%), Positives = 15/21 (71%)
 Frame = +3

Query: 107 KMRIHCLENVDKALQFLKEQR 127
           KMR H + NV+KAL+  + QR
Sbjct: 3   KMRFHKIANVNKALELHRLQR 65
>29446
          Length = 1445

 Score = 92.0 bits (227), Expect = 2e-18,   Method: Compositional matrix adjust.
 Identities = 55/141 (39%), Positives = 80/141 (56%), Gaps = 5/141 (3%)
 Frame = +3

Query: 53   EVVQKKTFTKWVNSHLARVSCRISDLYKDLRDGRMLIKLLEVLSGEMLPRPTK-GKMRIH 111
            +++QK TFT+W N HL  V+  I+DL  D  DG  L+ L+EVLSG+      K    R  
Sbjct: 993  KIIQKNTFTRWANEHLRTVNKAIADLESDFSDGLRLVALIEVLSGKKFKHVNKRPNFRTQ 1172

Query: 112  CLENVDKALQFLK-EQRVHLENMGSHDIVDGNHRLVLGLIWTIILRFQIQDIVVQTQEGR 170
             LENV   L+FL+ ++ + + N+ S DIVD   +L+LGLIWT+IL + I   + + +E  
Sbjct: 1173 KLENVTLTLKFLEDDEGIRIVNIDSTDIVDKKLKLILGLIWTLILHYSISMPMWEGEEPT 1352

Query: 171  ETR---SAKDALLLWCQMKTA 188
             +    + K  LL W Q K  
Sbjct: 1353 PSEGGPTPKQRLLNWIQSKVP 1415
>05733
          Length = 1021

 Score = 81.6 bits (200), Expect = 3e-15,   Method: Compositional matrix adjust.
 Identities = 42/103 (40%), Positives = 62/103 (60%), Gaps = 3/103 (2%)
 Frame = +2

Query: 178 ALLLWCQ--MKTAGYPHVNVTNFTSSWKDGLAFNALIHKHRPDLIDFDKLKDSNARHNLE 235
           +LL WCQ  +    Y  V++ +FTSSW+ GLAF ALIH  RP LI    L +     N +
Sbjct: 467 SLLRWCQRVLNXGTYRGVHIIDFTSSWRSGLAFCALIHAFRPHLISPASLMECETVKNNQ 646

Query: 236 HAFDVAERQLGIIPLLDPEDV-FTENPDEKSIITYVVAFYHYF 277
            AFDVA+++LGI P++  ED+     PD+ +++ Y+  F+  F
Sbjct: 647 LAFDVAQKELGIAPVMRGEDMAACAVPDKLTMVAYLSQFHELF 775
>34417
          Length = 1096

 Score = 81.3 bits (199), Expect = 4e-15,   Method: Compositional matrix adjust.
 Identities = 39/77 (50%), Positives = 50/77 (64%), Gaps = 1/77 (1%)
 Frame = +2

Query: 199 TSSWKDGLAFNALIHKHRPDLIDFDKLKDSNARHNLEHAFDVAERQLGIIPLLDPEDVF- 257
           +S W +GLAF ALIH   PD  D+ +L+  N R+N E AFD AE+   I PLLD ED+  
Sbjct: 38  SSCWNNGLAFCALIHHFYPDAFDYSQLQPQNRRYNFELAFDTAEKLADISPLLDVEDMIK 217

Query: 258 TENPDEKSIITYVVAFY 274
            +NPD K + TYV +FY
Sbjct: 218 MKNPDWKCVFTYVQSFY 268
>28965
          Length = 421

 Score = 80.1 bits (196), Expect = 9e-15,   Method: Compositional matrix adjust.
 Identities = 47/126 (37%), Positives = 72/126 (57%)
 Frame = +2

Query: 907  VNLAANNLVESGHPRSGEVKQYQDRLNKRWQAFQAVVSEQREAVDSALRVNNYCVDCEET 966
            VN  A  LV  GHP    ++Q Q+ +N+ W+  + +   ++E +  A  +  +  D +ET
Sbjct: 41   VNTLAEQLVTDGHPEEETIRQKQEEVNEAWKRLRQLSLLRQERLYGAHEIQRFNRDADET 220

Query: 967  SKWIMDKTKVVESTKDLGQDLAGVIAIQRKLSGLERDVLAIRDRVSALERESQYLMESHP 1026
              WI +K  V+ ST D G+DLA V  +QRK  G+ERD+ A+ ++V+AL  ES  L   H 
Sbjct: 221  IAWIQEKDAVL-STDDYGRDLASVQTLQRKHEGVERDLAALEEKVNALGTESVRLQGIHG 397

Query: 1027 EQKEDI 1032
            +Q E I
Sbjct: 398  DQSEQI 415

 Score = 58.5 bits (140), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 39/134 (29%), Positives = 71/134 (52%), Gaps = 1/134 (0%)
 Frame = +2

Query: 1744 QERVDNVNTIIERLIDAGHSEAATIAEWKDGLNDMWADLLELIDTRMQLLAASYDLHRYF 1803
            +++V  VNT+ E+L+  GH E  TI + ++ +N+ W  L +L   R + L  ++++ R+ 
Sbjct: 23   EDKVVEVNTLAEQLVTDGHPEEETIRQKQEEVNEAWKRLRQLSLLRQERLYGAHEIQRFN 202

Query: 1804 YTGTEILGLIDEKHRELP-EDVGLDASTAESFHRVHTAFERELHLLGVQVQQFQDVATRL 1862
                E +  I EK   L  +D G D ++ ++  R H   ER+L  L  +V      + RL
Sbjct: 203  RDADETIAWIQEKDAVLSTDDYGRDLASVQTLQRKHEGVERDLAALEEKVNALGTESVRL 382

Query: 1863 QTAYAGEKADAIQS 1876
            Q  + G++++ I S
Sbjct: 383  QGIH-GDQSEQIHS 421

 Score = 53.9 bits (128), Expect = 8e-07,   Method: Compositional matrix adjust.
 Identities = 35/111 (31%), Positives = 63/111 (56%)
 Frame = +2

Query: 1647 AQSLLSAGHPEGEQIIRLQGQVDKQYAGLKDMAEERRRRLENMYHLFQLKREADDLEQWI 1706
            A+ L++ GHPE E I + Q +V++ +  L+ ++  R+ RL   + + +  R+AD+   WI
Sbjct: 53   AEQLVTDGHPEEETIRQKQEEVNEAWKRLRQLSLLRQERLYGAHEIQRFNRDADETIAWI 232

Query: 1707 TEKEMVASSQEMGQDFDHVTMLRDKFRDFARETGAIGQERVDNVNTIIERL 1757
             EK+ V S+ + G+D   V  L+ K     R+  A+ +E+V+ + T   RL
Sbjct: 233  QEKDAVLSTDDYGRDLASVQTLQRKHEGVERDLAAL-EEKVNALGTESVRL 382

 Score = 53.5 bits (127), Expect = 9e-07,   Method: Compositional matrix adjust.
 Identities = 38/134 (28%), Positives = 67/134 (50%), Gaps = 7/134 (5%)
 Frame = +2

Query: 1942 LKYHQGIKAEINTRAKNFSTCLELGESLLQRQHQASDEIREKLQQVISRRQEMNDKWEA- 2000
            L+ H+    E+NT          L E L+   H   + IR+K       ++E+N+ W+  
Sbjct: 11   LQNHEDKVVEVNT----------LAEQLVTDGHPEEETIRQK-------QEEVNEAWKRL 139

Query: 2001 ------RSDRLHMLLEVCQFSRDASVAEAWLIAQEPYLASRDFGHTVDSVEKLIKRHEAF 2054
                  R +RL+   E+ +F+RDA    AW+  ++  L++ D+G  + SV+ L ++HE  
Sbjct: 140  RQLSLLRQERLYGAHEIQRFNRDADETIAWIQEKDAVLSTDDYGRDLASVQTLQRKHEGV 319

Query: 2055 EKSTASWAERFAAL 2068
            E+  A+  E+  AL
Sbjct: 320  ERDLAALEEKVNAL 361

 Score = 53.1 bits (126), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 28/97 (28%), Positives = 55/97 (56%)
 Frame = +2

Query: 604 DPQVIQDRVSHLEQCFSELSNMAAGRKAQLEQSKRLWKFFWEMDEAESWIKEKEQIYSSL 663
           + + I+ +   + + +  L  ++  R+ +L  +  + +F  + DE  +WI+EK+ + S+ 
Sbjct: 83  EEETIRQKQEEVNEAWKRLRQLSLLRQERLYGAHEIQRFNRDADETIAWIQEKDAVLSTD 262

Query: 664 DYGKDLTSVLILQRKHKAFEDELRGLDAHLKQIFQEA 700
           DYG+DL SV  LQRKH+  E +L  L+  +  +  E+
Sbjct: 263 DYGRDLASVQTLQRKHEGVERDLAALEEKVNALGTES 373

 Score = 47.0 bits (110), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 25/68 (36%), Positives = 41/68 (60%), Gaps = 3/68 (4%)
 Frame = +2

Query: 710 GHPQIET---RVKEVSAQWDHLKELAAFRKKDLQDAENFFQFQGDADDLKAWLQDAHRLL 766
           GHP+ ET   + +EV+  W  L++L+  R++ L  A    +F  DAD+  AW+Q+   +L
Sbjct: 74  GHPEEETIRQKQEEVNEAWKRLRQLSLLRQERLYGAHEIQRFNRDADETIAWIQEKDAVL 253

Query: 767 SGEDVGQD 774
           S +D G+D
Sbjct: 254 STDDYGRD 277

 Score = 44.7 bits (104), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 36/143 (25%), Positives = 68/143 (47%)
 Frame = +2

Query: 1524 QNEILGHAPRVEDVLRRGQELVKAAEIDCQDIEERLGHLQSSWDTLREAAAGRLQRLRDA 1583
            Q ++  H  +V +V    ++LV     + + I ++   +  +W  LR+ +  R +RL  A
Sbjct: 2    QKDLQNHEDKVVEVNTLAEQLVTDGHPEEETIRQKQEEVNEAWKRLRQLSLLRQERLYGA 181

Query: 1584 HEAQQYYLDAGEAEAWISEQELYVFSDEPPKDEEGAIVMLKRHLRQQRTVEEYGRNIKQL 1643
            HE Q++  DA E  AWI E++  + +D+  +D      + ++H       E   R++  L
Sbjct: 182  HEIQRFNRDADETIAWIQEKDAVLSTDDYGRDLASVQTLQRKH-------EGVERDLAAL 340

Query: 1644 AGRAQSLLSAGHPEGEQIIRLQG 1666
              +  +L       G + +RLQG
Sbjct: 341  EEKVNAL-------GTESVRLQG 388

 Score = 40.4 bits (93), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 29/95 (30%), Positives = 52/95 (54%), Gaps = 1/95 (1%)
 Frame = +2

Query: 1019 QYLMESHPEQKEDIGQRQADVEKLWKGL-QDALQGQELSLGEASKLQAFLQDLDDFKAWL 1077
            Q + + HPE+ E I Q+Q +V + WK L Q +L  QE   G A ++Q F +D D+  AW+
Sbjct: 59   QLVTDGHPEE-ETIRQKQEEVNEAWKRLRQLSLLRQERLYG-AHEIQRFNRDADETIAWI 232

Query: 1078 SMAQKAVASEDMPESLPEAEQLLQQHAAIKEEIDA 1112
                  ++++D    L   + L ++H  ++ ++ A
Sbjct: 233  QEKDAVLSTDDYGRDLASVQTLQRKHEGVERDLAA 337

 Score = 39.7 bits (91), Expect = 0.014,   Method: Compositional matrix adjust.
 Identities = 28/133 (21%), Positives = 63/133 (47%)
 Frame = +2

Query: 470 DTAAYEERVKALEDLAQELEKENYHDQKRIIARKDNILRLWSYXXXXXXXXXXXXXATLA 529
           D   +E++V  +  LA++L  + + +++ I  +++ +   W                   
Sbjct: 8   DLQNHEDKVVEVNTLAEQLVTDGHPEEETIRQKQEEVNEAWKRLRQLSLLRQERLYGAHE 187

Query: 530 LQKLFQDMLHSIDWMDEIKAHILSAEFGKHLLEVEDLLQKHKLMEADIAIQGDKVKAITA 589
           +Q+  +D   +I W+ E  A + + ++G+ L  V+ L +KH+ +E D+A   +KV A+  
Sbjct: 188 IQRFNRDADETIAWIQEKDAVLSTDDYGRDLASVQTLQRKHEGVERDLAALEEKVNALGT 367

Query: 590 ATLQFAEGKGYQP 602
            +++     G Q 
Sbjct: 368 ESVRLQGIHGDQS 406

 Score = 37.0 bits (84), Expect = 0.10,   Method: Compositional matrix adjust.
 Identities = 20/81 (24%), Positives = 45/81 (55%)
 Frame = +2

Query: 1872 DAIQSKEQEVSAAWQALLDACAGRRAQLVDTADKFRFFSMVRDLLSWMESIIRQIETQER 1931
            + I+ K++EV+ AW+ L      R+ +L    +  RF     + ++W++     + T + 
Sbjct: 89   ETIRQKQEEVNEAWKRLRQLSLLRQERLYGAHEIQRFNRDADETIAWIQEKDAVLSTDDY 268

Query: 1932 PRDVSSVELLLKYHQGIKAEI 1952
             RD++SV+ L + H+G++ ++
Sbjct: 269  GRDLASVQTLQRKHEGVERDL 331

 Score = 32.7 bits (73), Expect = 1.8,   Method: Compositional matrix adjust.
 Identities = 31/137 (22%), Positives = 64/137 (46%), Gaps = 1/137 (0%)
 Frame = +2

Query: 1321 ELASHQGWLENIDAEGRQLMAEKPQFKDVVSERLEALHKLWEELQSTAKAKAEQLSAARS 1380
            +L +H+  +  ++    QL+ +    ++ + ++ E +++ W+ L+  +  + E+L  A  
Sbjct: 8    DLQNHEDKVVEVNTLAEQLVTDGHPEEETIRQKQEEVNEAWKRLRQLSLLRQERLYGAHE 187

Query: 1381 SDLRLQTHADLN-KWIGAMEDQLRSDDLGKDLTTVNRMLAKLKRVEEQVNLRKEELEELF 1439
               R    AD    WI   +  L +DD G+DL +V  +  K + VE  +   +E++  L 
Sbjct: 188  IQ-RFNRDADETIAWIQEKDAVLSTDDYGRDLASVQTLQRKHEGVERDLAALEEKVNALG 364

Query: 1440 ADAPSLGAEAGDTDMSI 1456
             ++  L    GD    I
Sbjct: 365  TESVRLQGIHGDQSEQI 415

 Score = 30.8 bits (68), Expect = 7.6,   Method: Compositional matrix adjust.
 Identities = 11/45 (24%), Positives = 28/45 (62%)
 Frame = +2

Query: 1483 ISRDLEDETLWVEERLPLAQSADYGTNLQTVQLFMKKNQTLQNEI 1527
             +RD ++   W++E+  +  + DYG +L +VQ   +K++ ++ ++
Sbjct: 197  FNRDADETIAWIQEKDAVLSTDDYGRDLASVQTLQRKHEGVERDL 331
>38533
          Length = 380

 Score = 66.6 bits (161), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 40/120 (33%), Positives = 65/120 (54%), Gaps = 3/120 (2%)
 Frame = +1

Query: 1487 LEDETLWVE-ERLPLAQSADYGTNLQTVQLFMKKNQTLQNEILGHAPRVEDVLRRGQELV 1545
            +EDE  W   +R P+A+S D G +L  VQ  MKK+Q L++EI+ H P ++ V    Q+++
Sbjct: 1    VEDELSWYY*DRKPIAESTDLGNSLTAVQNLMKKHQALESEIVAHEPLIDAVATSAQQMI 180

Query: 1546 KAAEIDCQDIEERLGHLQSSWDTLREAAAGRLQRLRDA--HEAQQYYLDAGEAEAWISEQ 1603
            +       DI+ RL  L S     R      L ++  A    AQ++Y++  E E W++E+
Sbjct: 181  RTKHFATADIQTRLDDLTSP--AQRSQVFYLL*KVETAGCFGAQKFYMEVNEVELWMNEK 354

 Score = 37.0 bits (84), Expect = 0.091,   Method: Compositional matrix adjust.
 Identities = 31/112 (27%), Positives = 49/112 (43%), Gaps = 8/112 (7%)
 Frame = +1

Query: 553 SAEFGKHLLEVEDLLQKHKLMEADIAIQGDKVKAITAATLQFAEGKGYQPCDPQVIQDRV 612
           S + G  L  V++L++KH+ +E++I      + A+  +  Q    K +   D   IQ R+
Sbjct: 52  STDLGNSLTAVQNLMKKHQALESEIVAHEPLIDAVATSAQQMIRTKHFATAD---IQTRL 222

Query: 613 SHL------EQCFSEL--SNMAAGRKAQLEQSKRLWKFFWEMDEAESWIKEK 656
             L       Q F  L     A    AQ        KF+ E++E E W+ EK
Sbjct: 223 DDLTSPAQRSQVFYLL*KVETAGCFGAQ--------KFYMEVNEVELWMNEK 354
>19246
          Length = 440

 Score = 61.6 bits (148), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 32/96 (33%), Positives = 57/96 (59%), Gaps = 2/96 (2%)
 Frame = +2

Query: 2196 NKKASNRSWNNLYCVLRNSQLTFYKDAKNLALGVPYHGEEP-LALRHAICEIAVNY-KKK 2253
             KK S+RSW  ++ VLR   L   KD ++ +    +  EEP ++++  + +IA +Y +K+
Sbjct: 44   GKKCSDRSWKQVWAVLRGHALFLIKDRRDGSTHPTFSFEEPPISIKSCLVDIAHDYSRKR 223

Query: 2254 KHVFKLRLSNGSEWLFHGKDEEEMLMWLQSMSTAIN 2289
            KHVF+L   + S +L   +D+  M+ W+Q++ T  N
Sbjct: 224  KHVFRLTTYSESVYLLQAEDKGTMMSWIQAIKTNNN 331
>09100
          Length = 930

 Score = 55.8 bits (133), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 33/110 (30%), Positives = 58/110 (52%), Gaps = 7/110 (6%)
 Frame = +1

Query: 56  QKKTFTKWVNSHLARVSCR--ISDLYKDLRDGRMLIKLLEVLSGEMLPR----PTK-GKM 108
           Q   +  W+NS L +      I DL  D+RDG +   ++ ++S + +P     PT   +M
Sbjct: 463 QLSAYMAWINSQLKKKPGAHLIEDLRHDMRDGVVFADVIHIVSKQQIPGIQNVPTTLDEM 642

Query: 109 RIHCLENVDKALQFLKEQRVHLENMGSHDIVDGNHRLVLGLIWTIILRFQ 158
           R    +NVD+ L F+ + R+ +  + S DIV+GN + V+ LI  +   ++
Sbjct: 643 R----QNVDRVLHFMTQNRIKMHRISSRDIVEGNLKAVMRLILALAAHYK 780
>09711
          Length = 3041

 Score = 54.3 bits (129), Expect = 6e-07,   Method: Compositional matrix adjust.
 Identities = 54/222 (24%), Positives = 103/222 (46%), Gaps = 16/222 (7%)
 Frame = +1

Query: 56   QKKTFTKWVNSHLARVSCRISDLYKDLRDGRMLIKLLEVLSGEML------PRPTKGKMR 109
            ++KT+  W+NS    VS  +  LY DL DG ++ +L + +   ++       +  K K R
Sbjct: 850  EEKTYRNWMNS--LGVSPFVHHLYSDLYDGLIIFQLYDYIQPGLVDWSKVKKKFNKLKAR 1023

Query: 110  IHCLENVDKALQF---LKEQRVHLENMGSHDIVDGNHRLVLGLIWTIILRFQIQDIVVQT 166
               +EN + A++    +K  +V L  +   DI+DGN  L LGL+W ++  + +  +   T
Sbjct: 1024 FERIENCNYAVELGPQVKLVKVKLVGIAGQDILDGNPVLTLGLVWQLMRAYTLAILSKIT 1203

Query: 167  QEGRETRSAKDALLLWCQMKTAGYPHVNVTNFTS-SWKDGLAFNALIHKHRPDLIDFDKL 225
            +  +    + + ++ W   K        ++ F      DG+    +I   +P ++++D +
Sbjct: 1204 ENNKPI--SDNEIITWVNSKIK--KDDRISGFQDRKLNDGVIVARVIEAIKPGIVNWDNI 1371

Query: 226  KDSNAR------HNLEHAFDVAERQLGIIPLLDPEDVFTENP 261
             D +AR       N  +A  +A R++G      PED+    P
Sbjct: 1372 -DCSARDYQDRLTNARYAIGLA-RKIGAGVYALPEDIVEVKP 1491

 Score = 41.6 bits (96), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 61/266 (22%), Positives = 102/266 (38%), Gaps = 29/266 (10%)
 Frame = +1

Query: 56  QKKTFTKWVNSHLARVS-CR--------ISDLYKDLRDGRMLIKLLEVLSGEMLPRPTKG 106
           ++K F +W+N HL+    C+         + L+  + DG +L KL+       +   T  
Sbjct: 52  EQKAFAEWINRHLSDXPDCKHLLPLDADGTQLFGQMADGVLLCKLINHSVSNTIDERTIN 231

Query: 107 KMRIHCL---ENVDKALQFLKEQRVHLENMGSHDIVDGNHRLVLGLIWTIILRFQIQDIV 163
           K  +      EN+  A+           N+G  D+  G   LVLGL+W II    + DI 
Sbjct: 232 KQNLSLYRRHENLTLAVNSAGAIGCTTVNIGPEDLAAGRPHLVLGLLWQIIRIGLLSDIN 411

Query: 164 VQTQEG-------RET------RSAKDALLLWC--QMKTAGYPHVNVTNFTSSWKDGLAF 208
           +    G        ET       S +  LL W    +  AG     + NF    KD  A+
Sbjct: 412 LAHHPGLVNLLLDGETIEDLIRLSPEQILLRWVNYHLNRAGCDR-QIXNFGEDIKDSEAY 588

Query: 209 NALIHKHRPDL--IDFDKLKDSNARHNLEHAFDVAERQLGIIPLLDPEDVFTENPDEKSI 266
             L+ +  P    +    L   +     E     A++ +G    +   DV + N  +K  
Sbjct: 589 THLLKQISPPSAGVTLSPLSVGDVHQRAECMLQEADK-IGCRSFVGASDVVSGN--QKLN 759

Query: 267 ITYVVAFYHYFSKMKVLAVEGKRVGK 292
           + +V   ++ +  +    VE + V K
Sbjct: 760 LAFVANLFNNYPALDTPQVEVEDVMK 837
>25051
          Length = 1017

 Score = 51.6 bits (122), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 38/134 (28%), Positives = 65/134 (48%), Gaps = 4/134 (2%)
 Frame = -2

Query: 2175 DLGHTVQME-GYLGRKHDLEGPNKKA--SNRSWNNLYCVLRNSQLTFYKDAKNLALGVPY 2231
            D   TV+ + GY+ RK  +E   +K     R W  +Y +LR+  L  YKD   +  G   
Sbjct: 932  DPSKTVEYKKGYVMRKSCMEPGRRKTPFGKRGWRMVYTILRDLILYQYKDEHQVKKGQFV 753

Query: 2232 HGEEPLA-LRHAICEIAVNYKKKKHVFKLRLSNGSEWLFHGKDEEEMLMWLQSMSTAINE 2290
               + +  + HA+   A +Y KK+HVF+L+ ++ +E+LF      E+  W+ +++     
Sbjct: 752  ESSQNVVRIHHALATKASDYTKKQHVFRLQTADWAEYLFQTGGTIELQEWIDTINL---- 585

Query: 2291 SQSIRVKAQSLPLP 2304
               +     S PLP
Sbjct: 584  ---VAATLSSPPLP 552
>22703
          Length = 906

 Score = 50.8 bits (120), Expect = 6e-06,   Method: Compositional matrix adjust.
 Identities = 31/112 (27%), Positives = 55/112 (49%)
 Frame = -3

Query: 1959 FSTCLELGESLLQRQHQASDEIREKLQQVISRRQEMNDKWEARSDRLHMLLEVCQFSRDA 2018
            F    + G S +   H  S EI EK++Q+    + +    E R       LE  Q   + 
Sbjct: 880  FDKFRKTGRSFIANGHFLSKEIEEKIKQLDQSLEGLIRNLEHRRKLHQQNLEAQQLRHEM 701

Query: 2019 SVAEAWLIAQEPYLASRDFGHTVDSVEKLIKRHEAFEKSTASWAERFAALEK 2070
               EAW+  +EP L  + FG +++  E++++RH+ F K+  +  +R  AL++
Sbjct: 700  EQIEAWMNLREPLLKEKKFGESIEGAEEMLRRHD*F*KTVTAQEDRVNALQR 545
>11159
          Length = 520

 Score = 48.9 bits (115), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 24/85 (28%), Positives = 48/85 (56%), Gaps = 1/85 (1%)
 Frame = +2

Query: 2202 RSWNNLYCVLRNSQLTFYKDAKNLALG-VPYHGEEPLALRHAICEIAVNYKKKKHVFKLR 2260
            RSW   +  LR+  L  +KD        +  +    + + HA+  +A +Y KK+HVF+L+
Sbjct: 65   RSWKMFFITLRDLVLYLHKDEHGFRKSQMSDNLHNAIRIHHALATMANDYTKKQHVFRLQ 244

Query: 2261 LSNGSEWLFHGKDEEEMLMWLQSMS 2285
             ++ +E+LF   D +E+  W+++++
Sbjct: 245  TADQAEYLFQTSDSKELHSWVETIN 319
>17567
          Length = 448

 Score = 48.9 bits (115), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 29/139 (20%), Positives = 67/139 (48%)
 Frame = -3

Query: 530 LQKLFQDMLHSIDWMDEIKAHILSAEFGKHLLEVEDLLQKHKLMEADIAIQGDKVKAITA 589
           L  +F+++    + + E+++ ++  ++GKHL   +D+L++H L EA +     +V+ +  
Sbjct: 392 LMAMFREIESIQEELKEVQSKVVGEDYGKHLQATQDMLEQHSLQEAQLQALTRRVRKLNR 213

Query: 590 ATLQFAEGKGYQPCDPQVIQDRVSHLEQCFSELSNMAAGRKAQLEQSKRLWKFFWEMDEA 649
            +         Q    Q +  R+  L    + +   +  R+  LE +++ ++F  + +E 
Sbjct: 212 KS---------QGAQEQSLDKRLEALNAQLNNVQAQSDKRRQGLETAQQYYQFLQDTEEE 60

Query: 650 ESWIKEKEQIYSSLDYGKD 668
           + W+ E+     S   GKD
Sbjct: 59  DRWVGERIDAVRSPSLGKD 3

 Score = 39.7 bits (91), Expect = 0.013,   Method: Compositional matrix adjust.
 Identities = 32/146 (21%), Positives = 75/146 (51%)
 Frame = -3

Query: 629 RKAQLEQSKRLWKFFWEMDEAESWIKEKEQIYSSLDYGKDLTSVLILQRKHKAFEDELRG 688
           RK+ L     L   F E++  +  +KE +      DYGK L +   +  +H   E +L+ 
Sbjct: 422 RKSTLSGYNNLMAMFREIESIQEELKEVQSKVVGEDYGKHLQATQDMLEQHSLQEAQLQA 243

Query: 689 LDAHLKQIFQEADDMVAQKQFGHPQIETRVKEVSAQWDHLKELAAFRKKDLQDAENFFQF 748
           L   ++++ +++    AQ+Q     ++ R++ ++AQ ++++  +  R++ L+ A+ ++QF
Sbjct: 242 LTRRVRKLNRKSQG--AQEQ----SLDKRLEALNAQLNNVQAQSDKRRQGLETAQQYYQF 81

Query: 749 QGDADDLKAWLQDAHRLLSGEDVGQD 774
             D ++   W+ +    +    +G+D
Sbjct: 80  LQDTEEEDRWVGERIDAVRSPSLGKD 3

 Score = 30.8 bits (68), Expect = 6.9,   Method: Compositional matrix adjust.
 Identities = 19/61 (31%), Positives = 33/61 (54%)
 Frame = -3

Query: 1350 VSERLEALHKLWEELQSTAKAKAEQLSAARSSDLRLQTHADLNKWIGAMEDQLRSDDLGK 1409
            + +RLEAL+     +Q+ +  + + L  A+     LQ   + ++W+G   D +RS  LGK
Sbjct: 185  LDKRLEALNAQLNNVQAQSDKRRQGLETAQQYYQFLQDTEEEDRWVGERIDAVRSPSLGK 6

Query: 1410 D 1410
            D
Sbjct: 5    D 3
>32371
          Length = 625

 Score = 37.0 bits (84), Expect(2) = 2e-05,   Method: Compositional matrix adjust.
 Identities = 21/48 (43%), Positives = 27/48 (56%), Gaps = 1/48 (2%)
 Frame = -2

Query: 217 PDLIDFDKLKDSNARHNLEHAFDVAERQLGIIPLLDPED-VFTENPDE 263
           PDLID+D L   N  +N   AF VAE++L I   L+  D V    PD+
Sbjct: 549 PDLIDYDSLSKENVLYNNNLAFTVAEQELDIPAFLEAADMVALRTPDK 406

 Score = 31.2 bits (69), Expect(2) = 2e-05,   Method: Composition-based stats.
 Identities = 11/24 (45%), Positives = 18/24 (75%)
 Frame = -1

Query: 193 VNVTNFTSSWKDGLAFNALIHKHR 216
           V++ +   SW++GLAF A+IH+ R
Sbjct: 622 VDIKDLLVSWRNGLAFCAIIHRFR 551
>18202
          Length = 424

 Score = 45.8 bits (107), Expect = 2e-04,   Method: Composition-based stats.
 Identities = 34/133 (25%), Positives = 64/133 (48%), Gaps = 6/133 (4%)
 Frame = -1

Query: 58  KTFTKWVNSHLARVSCRISDLYKDLRDGRMLIKLLEVLSGEMLPRPTKGKMRIHCLENVD 117
           + +  W NS L  V+  + ++   +++GR+L +L++VL+      P  G +         
Sbjct: 385 QVYLSWANSVLCEVNSSVENV-SSIQEGRVLCELIDVLA------PEAGLLDKVQASGKS 227

Query: 118 KALQFLKEQRVHLENMG------SHDIVDGNHRLVLGLIWTIILRFQIQDIVVQTQEGRE 171
               F+     H++N G      + DI+DG+ + +L ++W +IL + I  I   + + R 
Sbjct: 226 GQRAFIYAALDHMKNHGIKIVFSTQDIMDGDIKSLLDVMWLLILNYGIHFIGNNSFQ-RS 50

Query: 172 TRSAKDALLLWCQ 184
             + K  LL WCQ
Sbjct: 49  VGAGKKNLLDWCQ 11
>32088
          Length = 1928

 Score = 42.7 bits (99), Expect = 0.002,   Method: Composition-based stats.
 Identities = 39/143 (27%), Positives = 59/143 (41%), Gaps = 17/143 (11%)
 Frame = +1

Query: 56   QKKTFTKWVN---------SHLARVSCRISDLYKDLRDGRMLIKLLEVLSGEMLPRPTKG 106
            ++K F  W+N          HL  V+    DL+K + DG +L KL+       +      
Sbjct: 1264 EQKAFAAWINRHLKDDPDCKHLMEVNEEGDDLFKKVGDGILLCKLINHSVSNTIDERAIN 1443

Query: 107  KMRI---HCLENVDKALQFLKEQRVHLENMGSHDIVDGNHRLVLGLIWTIILRFQIQDIV 163
            K  +   H  EN+  A+           N+G  D+  G   LVLGL+W II    + DI 
Sbjct: 1444 KSNLNVYHRHENLTLAVNSAGSIGCTTVNIGPEDLAAGRPHLVLGLLWQIIRIGLLSDIN 1623

Query: 164  VQTQEG-----RETRSAKDALLL 181
            +    G     RE  + +D + L
Sbjct: 1624 LAHHPGLVNLLREGETIEDFMRL 1692
>18556
          Length = 799

 Score = 42.0 bits (97), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 25/71 (35%), Positives = 37/71 (52%), Gaps = 1/71 (1%)
 Frame = +2

Query: 178 ALLLWCQMKTAGYPHV-NVTNFTSSWKDGLAFNALIHKHRPDLIDFDKLKDSNARHNLEH 236
           +LL W  ++ A Y     +   +  +++G    ALI + RPDLID+   KD +     E 
Sbjct: 44  SLLRWISVQLAAYQFTAELKEPSDVFRNGRVLCALISRFRPDLIDYAATKDMSPLECNEL 223

Query: 237 AFDVAERQLGI 247
           AF V ER+L I
Sbjct: 224 AFAVLERELHI 256
>19732
          Length = 2338

 Score = 39.7 bits (91), Expect = 0.013,   Method: Compositional matrix adjust.
 Identities = 28/118 (23%), Positives = 47/118 (39%), Gaps = 6/118 (5%)
 Frame = -2

Query: 2196 NKKASNRSWNNLYCVLRNSQLTFY------KDAKNLALGVPYHGEEPLALRHAICEIAVN 2249
            N       W  +Y VLR+  L  +      K  + + LG    GE+ +  R A       
Sbjct: 1728 NDPFKGHVWKPVYVVLRDFMLCVFANKTDSKPQQYVRLG----GEQCVGCRLA------T 1579

Query: 2250 YKKKKHVFKLRLSNGSEWLFHGKDEEEMLMWLQSMSTAINESQSIRVKAQSLPLPSLA 2307
             +++ +  ++ L+ G  W      EEE+  W QS+  A++E          LP  S+ 
Sbjct: 1578 SQERSYCIEIILATGGSWFLSVPTEEEVASWRQSLCLAVSEGMQDSSNLTCLPCVSVV 1405
>04951
          Length = 2852

 Score = 39.3 bits (90), Expect = 0.019,   Method: Composition-based stats.
 Identities = 36/158 (22%), Positives = 73/158 (46%), Gaps = 9/158 (5%)
 Frame = +1

Query: 113 LENVDKALQF---LKEQRVHLENMGSHDIVDGNHRLVLGLIWTIILRFQIQDIVVQTQEG 169
           +EN + A+Q    +K  ++ L  +G  DI DGN  L LGL+W ++  + +  +   T++ 
Sbjct: 7   IENCEYAVQLGPQMKVCKMKLVGIGGKDIHDGNPVLTLGLVWQLMRAYTLAILSKLTEDK 186

Query: 170 RETRSAKDALLLWCQMKTAGYPHVNVTNFTSSWKDGLAFNALIHKHRPDLIDFDKLKDSN 229
           +  + ++  ++ W   K      +      S   DG+    +I   +P +++++ + + N
Sbjct: 187 KPIQDSE--IVDWVNSKVKKDERIGSFQ-DSKLNDGVIVAKVIESIKPGIVNWENI-NPN 354

Query: 230 ARH------NLEHAFDVAERQLGIIPLLDPEDVFTENP 261
           A        N  +A  +A R++G      PED+    P
Sbjct: 355 ASEPDDRLANARYAIGLA-RKIGAGVYALPEDIVEVKP 465
>22686
          Length = 934

 Score = 35.0 bits (79), Expect = 0.35,   Method: Composition-based stats.
 Identities = 21/79 (26%), Positives = 35/79 (44%)
 Frame = +1

Query: 2166 EPTTLPAQRDLGHTVQMEGYLGRKHDLEGPNKKASNRSWNNLYCVLRNSQLTFYKDAKNL 2225
            +P  LP+ R + H+++   +   KH  +GP  +A NR+W N   +L      F    KN 
Sbjct: 553  QPAQLPSPRXVAHSLESVKFC--KHKEKGPTHEALNRNWQNEISILLLDFRNFGTKRKNE 726

Query: 2226 ALGVPYHGEEPLALRHAIC 2244
                       + L+H +C
Sbjct: 727  TKKTGQD*VHCVKLQHVVC 783
>29521
          Length = 903

 Score = 33.1 bits (74), Expect = 1.5,   Method: Composition-based stats.
 Identities = 19/56 (33%), Positives = 31/56 (55%), Gaps = 3/56 (5%)
 Frame = +3

Query: 2178 HTVQMEGYLGRKHDLEGPNKKASNR--SWNNLYCVLRNSQLTFYKDAKNL-ALGVP 2230
            H V +     R+ +  G   K  NR  +W+  YC+L+++ L +YK+  +L ALG P
Sbjct: 273  HNVGLPALEVRRPECTGYLLKVGNRRRTWHRRYCILKDACLYYYKNMNSLSALGWP 440
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|29293809|ref|NP_598798.1| ATP citrate lyase [Mus
musculus]
         (1091 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

37263                                                                 422   e-118
20406                                                                 177   3e-44
25088                                                                  60   2e-13
10791                                                                  32   1.4  
19377                                                                  30   3.6  
01159                                                                  30   4.8  
>37263
          Length = 743

 Score =  422 bits (1086), Expect = e-118,   Method: Compositional matrix adjust.
 Identities = 194/247 (78%), Positives = 224/247 (90%)
 Frame = +3

Query: 830  FMTSICDERGQELIYAGMPITEVFKEEMGIGGVLGLLWFQRRLPKYSCQFIEMCLMVTAD 889
            FMTSICDERGQELIYAGMPI+EV  +++GIGGV+ LLWFQR LP Y C+F EMCLMVTAD
Sbjct: 3    FMTSICDERGQELIYAGMPISEVLNKDVGIGGVISLLWFQRCLPPYVCKFFEMCLMVTAD 182

Query: 890  HGPAVSGAHNTIICARAGKDLVSSLTSGLLTIGDRFGGALDAAAKMFSKAFDSGIIPMEF 949
            HGPAVSGAHNTI+CARAGKDLVSS+ SGLLTIGDRFGGALD +A+ FS+A+D+ + PMEF
Sbjct: 183  HGPAVSGAHNTIVCARAGKDLVSSVVSGLLTIGDRFGGALDGSARQFSEAYDTNLHPMEF 362

Query: 950  VNKMKKEGKLIMGIGHRVKSINNPDMRVQILKDFVKQHFPATPLLDYALEVEKITTSKKP 1009
            VNKM+KEGKLI+GIGHRVKSINNPD+RV+I+K+FV ++FP  PLL YALEVEKITT+KKP
Sbjct: 363  VNKMRKEGKLILGIGHRVKSINNPDVRVKIIKEFVMENFPQCPLLKYALEVEKITTTKKP 542

Query: 1010 NLILNVDGFIGVAFVDMLRNCGSFTREEADEYVDIGALNGIFVLGRSMGFIGHYLDQKRL 1069
            NLILNVDG I  AFVDMLRN GSFT EEA EY+++GA+N +FVLGRS+GFIGHY+DQKRL
Sbjct: 543  NLILNVDGVIATAFVDMLRNSGSFTSEEAQEYINVGAINSLFVLGRSIGFIGHYMDQKRL 722

Query: 1070 KQGLYRH 1076
            KQGLYRH
Sbjct: 723  KQGLYRH 743
>20406
          Length = 444

 Score =  177 bits (448), Expect = 3e-44,   Method: Compositional matrix adjust.
 Identities = 94/134 (70%), Positives = 108/134 (80%)
 Frame = +2

Query: 306 EYSGAPSEQQTYDYAKTILSLMTREKHPEGKILIIGGSIANFTNVAATFKGIVRAIRDYQ 365
           EYSGAPSEQQTY+YAKT+LSLMT +  P GKILIIGG IANFTNVA TFKGIVRA++++Q
Sbjct: 2   EYSGAPSEQQTYEYAKTVLSLMTEQVDPRGKILIIGGGIANFTNVATTFKGIVRALQEFQ 181

Query: 366 GPLKEHEVTIFVRRGGPNYQEGLRVMGEVGKTTGIPIHVFGTETHMTAIVGMALGHRPIP 425
           G L E +V ++VRR GPNYQEGLR+M E+  + G+PIHVFG ETHMTAIV MALG R IP
Sbjct: 182 GKLIEGKVVVYVRRAGPNYQEGLRIMRELSSSLGVPIHVFGPETHMTAIVSMALGKRDIP 361

Query: 426 NQPPTAAHTANFLL 439
             P     TANFLL
Sbjct: 362 TTPKALPTTANFLL 403
>25088
          Length = 1646

 Score = 60.5 bits (145), Expect(2) = 2e-13,   Method: Compositional matrix adjust.
 Identities = 46/150 (30%), Positives = 74/150 (49%), Gaps = 1/150 (0%)
 Frame = +1

Query: 541 PVFKNMADAMKKHPEVDVLINFASLRSAYDSTMETMNYAQIRTIAIIAEGIPEA-LTRKL 599
           PVF ++ +A+ K    D  + F     A  + +E ++ A+I  +  I EGIP+  + R  
Sbjct: 253 PVFNSVQEAVDK-TGADATVIFVPPPFAAAAILEAID-AEISLVVCITEGIPQQDMVRVK 426

Query: 600 IKKADQKGVTIIGPATVGGIKPGCFKIGNTGGMLDNILASKLYRPGSVAYVSRSGGMSNE 659
            +   Q    +IGP   G IKPG  KIG        I+   +++ G +  VSRSG ++ E
Sbjct: 427 HRLVRQNKTRLIGPNCPGIIKPGEIKIG--------IMPGHIHQKGKIGIVSRSGTLTYE 582

Query: 660 LNNIISRTTDGVYEGVAIGGDRYPGSTFMD 689
             +  ++   G    V IGGD + G+ F+D
Sbjct: 583 AVHQTTQVGLGQSLCVGIGGDPFNGTNFID 672

 Score = 34.7 bits (78), Expect(2) = 2e-13,   Method: Compositional matrix adjust.
 Identities = 34/100 (34%), Positives = 45/100 (45%), Gaps = 3/100 (3%)
 Frame = +3

Query: 698 PGVKMIVVLGEIGGTEEYKICRGIKE---GRLTKPVVCWCIGTCATMFSSEVQFGHAGAC 754
           P  + IV++GEIGG  E      +K    G   KPVV +  G  A       + GHAGA 
Sbjct: 696 PQTEGIVLIGEIGGQAEENAADYLKNHNTGPKAKPVVSFIAGLTA---PPGRRMGHAGAI 866

Query: 755 ANQASETAVAKNQALKEAGVFVPRSFDELGEIIQSVYEDL 794
                  A  K ++LK AGV V  S  +LG  +    E +
Sbjct: 867 IAGGKGGANEKIESLKSAGVEVSMSPAQLGTTMLQAMEKM 986
>10791
          Length = 808

 Score = 32.0 bits (71), Expect = 1.4,   Method: Composition-based stats.
 Identities = 11/31 (35%), Positives = 20/31 (64%)
 Frame = +3

Query: 849 ITEVFKEEMGIGGVLGLLWFQRRLPKYSCQF 879
           +T+   E+   G +L  LW QR+LP ++C++
Sbjct: 393 VTKTHFEKQKGGQILNKLWIQRKLPSFNCRY 485
>19377
          Length = 707

 Score = 30.4 bits (67), Expect = 3.6,   Method: Composition-based stats.
 Identities = 10/27 (37%), Positives = 20/27 (74%)
 Frame = +2

Query: 853 FKEEMGIGGVLGLLWFQRRLPKYSCQF 879
           F+++ G G +L  +W QR+LP ++C++
Sbjct: 473 FEKQKG-GQILNKIWIQRKLPSFNCRY 550
>01159
          Length = 2613

 Score = 30.0 bits (66), Expect = 4.8,   Method: Compositional matrix adjust.
 Identities = 21/46 (45%), Positives = 26/46 (56%), Gaps = 2/46 (4%)
 Frame = +3

Query: 256 LDAKSGASLKLTLLNPKGRIWTMVAGGGASVVYSD--TICDLGGVN 299
           L AKS AS+  T L PKG    MV+G G   V +D  TI D+  V+
Sbjct: 207 LAAKSVASILKTSLGPKGLDKMMVSGDGDVTVTNDGATILDMMDVD 344
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|45598396|ref|NP_035288.2| protein kinase, cAMP
dependent regulatory, type II beta [Mus musculus]
         (416 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

08195                                                                 419   e-118
27710                                                                 137   7e-33
18204                                                                  98   7e-21
20517                                                                  46   3e-05
27148                                                                  30   2.5  
27853                                                                  30   2.6  
>08195
          Length = 2165

 Score =  419 bits (1078), Expect = e-118,   Method: Compositional matrix adjust.
 Identities = 216/420 (51%), Positives = 277/420 (65%), Gaps = 9/420 (2%)
 Frame = -3

Query: 1    MSIEIPAGLTELLQGFTVEVLRHQPADLLEFALQHFTRLQQENER-------KGAARFGH 53
            MS +IP GLTELLQ FTV  LR +P+DL++FA  +F RL+  N          G  RF  
Sbjct: 2031 MSFDIPPGLTELLQEFTVAALRERPSDLVDFAASYFNRLRLLNGDAVDPKCFTGGVRFSQ 1852

Query: 54   EGRTWGDXXXXXXXXIPSKGVNFAEEPMRSDSXXXXXXXXXXXXXXXXPVIN--RFTRRA 111
             G             I +    FA+     D                 P  N  RF RR 
Sbjct: 1851 TG-----------SHILAHNGTFAQNNSDDDEAMLEP-----------PPSNTARF-RRK 1741

Query: 112  SVCAEAYNPDEEEDDAESRIIHPKTDDQRNRLQEACKDILLFKNLDPEQMSQVLDAMFEK 171
            SV AEAYNP+ +ED  E++I++PK+D QR RL +  K+ILLF++LDPEQM +VLDAMFEK
Sbjct: 1740 SVSAEAYNPETDEDGGEAKIVNPKSDIQRQRLADVVKNILLFRSLDPEQMQEVLDAMFEK 1561

Query: 172  LVKEGEHVIDQGDDGDNFYVIDRGTFDIYVKCDGVGRCVGNYDNRGSFGELALMYNTPRA 231
             V+ GEH+IDQGDDGDNFYVID GT+DIYV  +G  + VGNYDN G FGELALMYN PRA
Sbjct: 1560 SVQPGEHIIDQGDDGDNFYVIDSGTYDIYVDVEGQAKLVGNYDNSGFFGELALMYNMPRA 1381

Query: 232  ATITATSPGALWGLDRVTFRRIIVKNNAKKRKMYESFIESLPFLKSLEVSERLKVVDVIG 291
            ATI A+S G +W LDR TFRRI++K   +KRK YES +ES+P LKSL++ ER+ V D + 
Sbjct: 1380 ATIIASSTGTIWALDRTTFRRIVLKTAFQKRKKYESLLESVPLLKSLDLYERMNVADALQ 1201

Query: 292  TKVYNDGEQIIAQGDLADSFFIVESGEVKITMKRKGKSEVEENGAVEIARCFRGQYFGEL 351
            T+ Y DG QII QGD AD  + VESG+V+I M  K +S     G  ++    +G YFGEL
Sbjct: 1200 TRTYEDGVQIIKQGDAADVMYFVESGQVRIAMTNK-ESTDPSAGETDVTVLEKGGYFGEL 1024

Query: 352  ALVTNKPRAASAHAIGTVKCLAMDVQAFERLLGPCMEIMKRNIATYEEQLVALFGTNMDI 411
            AL+T++PRAASA+A GTVKC  +DV AFERL+GPCM+++KRNI  Y+ Q+ ++FG ++ +
Sbjct: 1023 ALITHQPRAASAYAQGTVKCAVLDVHAFERLMGPCMDVLKRNIDDYDSQISSIFGKSVSM 844
>27710
          Length = 429

 Score =  137 bits (345), Expect = 7e-33,   Method: Compositional matrix adjust.
 Identities = 68/141 (48%), Positives = 93/141 (65%)
 Frame = +2

Query: 177 EHVIDQGDDGDNFYVIDRGTFDIYVKCDGVGRCVGNYDNRGSFGELALMYNTPRAATITA 236
           E++I QGD+GDNFYVID G  D++V  +     V      GSFGELAL+Y TPRAAT+ A
Sbjct: 2   ENIIQQGDEGDNFYVIDVGEVDVFVNSE----LVTTISEGGSFGELALIYGTPRAATVRA 169

Query: 237 TSPGALWGLDRVTFRRIIVKNNAKKRKMYESFIESLPFLKSLEVSERLKVVDVIGTKVYN 296
            S   LWG+DR ++RRI++ +  +KRKMYE F+  +  L+SL+  ERL V D + T  ++
Sbjct: 170 KSDVKLWGIDRDSYRRILMGSTIRKRKMYEEFLSRVSILESLDKWERLTVADSLETCAFD 349

Query: 297 DGEQIIAQGDLADSFFIVESG 317
           DGE I+ QG   D F+I+  G
Sbjct: 350 DGETIVKQGAAGDDFYIILEG 412

 Score = 55.8 bits (133), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 36/103 (34%), Positives = 54/103 (52%)
 Frame = +2

Query: 299 EQIIAQGDLADSFFIVESGEVKITMKRKGKSEVEENGAVEIARCFRGQYFGELALVTNKP 358
           E II QGD  D+F++++ GEV + +  +  + + E G+           FGELAL+   P
Sbjct: 2   ENIIQQGDEGDNFYVIDVGEVDVFVNSELVTTISEGGS-----------FGELALIYGTP 148

Query: 359 RAASAHAIGTVKCLAMDVQAFERLLGPCMEIMKRNIATYEEQL 401
           RAA+  A   VK   +D  ++ R+L     I KR +  YEE L
Sbjct: 149 RAATVRAKSDVKLWGIDRDSYRRILMGST-IRKRKM--YEEFL 268

 Score = 37.4 bits (85), Expect = 0.012,   Method: Compositional matrix adjust.
 Identities = 20/70 (28%), Positives = 36/70 (51%)
 Frame = +2

Query: 126 DAESRIIHPKTDDQRNRLQEACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDD 185
           D+  RI+   T  +R   +E    + + ++LD  +   V D++      +GE ++ QG  
Sbjct: 203 DSYRRILMGSTIRKRKMYEEFLSRVSILESLDKWERLTVADSLETCAFDDGETIVKQGAA 382

Query: 186 GDNFYVIDRG 195
           GD+FY+I  G
Sbjct: 383 GDDFYIILEG 412
>18204
          Length = 429

 Score = 97.8 bits (242), Expect = 7e-21,   Method: Compositional matrix adjust.
 Identities = 53/148 (35%), Positives = 85/148 (57%)
 Frame = -1

Query: 218 SFGELALMYNTPRAATITATSPGALWGLDRVTFRRIIVKNNAKKRKMYESFIESLPFLKS 277
           +FGELA++YN  R A++ A +   +W LDR  F+ I++K   ++R+    F++S+  L+ 
Sbjct: 429 AFGELAILYNCTRTASVKAVTDVKVWVLDRQMFQAIMMKTGLQRREENIRFLKSVSVLRD 250

Query: 278 LEVSERLKVVDVIGTKVYNDGEQIIAQGDLADSFFIVESGEVKITMKRKGKSEVEENGAV 337
           L   +  K+ DV+    +++GE II +G   D+FF++  GEV++T    G  E +     
Sbjct: 249 LPSDKLAKIADVLEIDFFHEGEFIIREGCTGDTFFLINKGEVRVTQTVAGHEEPQ----- 85

Query: 338 EIARCFRGQYFGELALVTNKPRAASAHA 365
           EI +  RG YFGE AL+    R AS  A
Sbjct: 84  EIRKLKRGDYFGEKALLGEDRRTASCIA 1
>20517
          Length = 749

 Score = 45.8 bits (107), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 43/168 (25%), Positives = 74/168 (44%), Gaps = 18/168 (10%)
 Frame = +3

Query: 184 DDGDNFYVIDRGTFDI--YVKCDGVGRCVGNYDNRGSFGELALMYNTPRAATITATSPGA 241
           D   +FY I  GT  +  + +     R +   D   SFGELA++  + R AT++  +   
Sbjct: 6   DPPRSFYFILSGTVVVTQFERQYSTTRTLVTLDQGMSFGELAVITGSRRQATVSTMTEVE 185

Query: 242 LWGLDRVTFRRIIVKNNAKKRKM-----YESFIESLPFLKSLEVSERLKVVDVIGTKVYN 296
           L  +    F  I +   A  RK+     +  F+ S+ FLK+  V +  +         +N
Sbjct: 186 LLCISAKDFEDIFM---AGGRKIITDPDHNKFLRSVDFLKAWPVQQLAQHPHACMFHYFN 356

Query: 297 DGEQIIAQGDLADSFFIVESGEVKITMK-----------RKGKSEVEE 333
            G+ ++   + +D  +IV+SG + +  K            +GKSEV E
Sbjct: 357 RGQVLVRDSNNSDWIYIVKSGSLSVMKKLHHATATDRHSTEGKSEVAE 500
>27148
          Length = 718

 Score = 29.6 bits (65), Expect = 2.5,   Method: Compositional matrix adjust.
 Identities = 14/32 (43%), Positives = 20/32 (62%)
 Frame = -3

Query: 205 GVGRCVGNYDNRGSFGELALMYNTPRAATITA 236
           GV + V  Y+   SFGELA+M  T R +T+ +
Sbjct: 314 GVAKTVMYYNRGDSFGELAIMNATRRQSTVIS 219
>27853
          Length = 864

 Score = 29.6 bits (65), Expect = 2.6,   Method: Compositional matrix adjust.
 Identities = 17/68 (25%), Positives = 32/68 (47%), Gaps = 1/68 (1%)
 Frame = +2

Query: 167 AMFEKLVKEGEHVIDQGDDGDNFYVIDRGTF-DIYVKCDGVGRCVGNYDNRGSFGELALM 225
           A+  ++ + G+ +  QGD+ D+ Y++  G    +     G    VG Y      G + ++
Sbjct: 215 ALDWQMTEAGKALFRQGDNSDSVYIVLTGRLRSVITLLGGKKEVVGEYGRGELVGIVEVL 394

Query: 226 YNTPRAAT 233
            +T RA T
Sbjct: 395 THTERATT 418
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31981588|ref|NP_598587.2| ATPase, H+ transporting,
lysosomal V1 subunit H [Mus musculus]
         (483 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

15926                                                                 360   e-116
13491                                                                 187   6e-48
26430                                                                 178   3e-45
33274                                                                  28   5.6  
>15926
          Length = 2059

 Score =  360 bits (925), Expect(2) = e-116,   Method: Compositional matrix adjust.
 Identities = 180/349 (51%), Positives = 242/349 (69%), Gaps = 2/349 (0%)
 Frame = -2

Query: 79   NLMTHISKEQTVQYILTMVDDMLQENHQRVSIFFDYAKRSKSTAWPYFLPMLNRQDPFTV 138
            +L+  I+K+QT+QYILT++DD LQE+  RV IF +YA++ K + W  F  +L R D F V
Sbjct: 2055 SLIDKIAKDQTLQYILTLLDDALQEDPSRVEIFREYARKRKESVWQPFFQLLERSDLFIV 1876

Query: 139  HMAARIIAKLAAWGKELMEGSDLNYYFNWIKTQLSSQKLRGSGVAVETGTISSSDSSQYV 198
            H ++RI+AK+A W KE ME   L  Y  W++ QL                     +++Y 
Sbjct: 1875 HQSSRIVAKIACWSKESMEKKSLQSYLIWLRDQLRLT------------------NNEYQ 1750

Query: 199  QCVAGCLQLMLRVNEYRFAWVEADGVNCIMGVLSN--KCGFQLQYQMIFSIWLLAFSPQM 256
              VA CLQ+M+R + YR  +VE DG+  I  VL+N  K GFQ+ YQ++F +W L+F+P++
Sbjct: 1749 STVARCLQMMVRNDIYRXVFVEVDGIAVISSVLANSEKIGFQMVYQLVFCLWCLSFNPRV 1570

Query: 257  CEHLRRYNIIPVLSDILQESVKEKVTRIILAAFRNFLEKSTERETRQEYALAMIQCKVLK 316
             E +   N+IP L+ IL  + +EKVTRIILA FRN L K  E    Q+YAL+M++ KV+K
Sbjct: 1569 AEQMSGMNLIPGLTYILGSTQREKVTRIILALFRNMLSKPEENTVIQDYALSMVRHKVVK 1390

Query: 317  QLENLEQQKYDDEDISEDIKFLLEKLGESVQDLSSFDEYSSELKSGRLEWSPVHKSEKFW 376
            QLE LE +K++D D+ EDI ++ +KL  SV DLSSFDEY SE+KSG LEWSPVHK+++FW
Sbjct: 1389 QLELLEARKWEDPDLEEDITWISQKLESSVHDLSSFDEYVSEVKSGNLEWSPVHKTDRFW 1210

Query: 377  RENAVRLNEKNYELLKILTKLLEVSDDPQVLAVAAHDVGEYVRHYPRGK 425
            RENA+RLNE NYELLKIL +LLE S D  VL+VAAHD+GEYVR+YPRGK
Sbjct: 1209 RENAMRLNEHNYELLKILVRLLETSRDALVLSVAAHDIGEYVRYYPRGK 1063

 Score = 77.4 bits (189), Expect(2) = e-116,   Method: Compositional matrix adjust.
 Identities = 35/57 (61%), Positives = 46/57 (80%)
 Frame = -1

Query: 422  PRGKRVIEQLGGKQLVMNHMHHEDQQVRYNALLAVQKLMVHNWEYLGKQLQSEQPQT 478
            PR + +IEQLG KQ VM ++ HED  VRY AL+AVQKLMVHNWEYLG+++  +QP++
Sbjct: 1072 PR-QNIIEQLGAKQRVMQYLTHEDPNVRYEALIAVQKLMVHNWEYLGRKMTEDQPKS 905
>13491
          Length = 465

 Score =  187 bits (476), Expect = 6e-48,   Method: Compositional matrix adjust.
 Identities = 84/119 (70%), Positives = 102/119 (85%)
 Frame = -1

Query: 360 KSGRLEWSPVHKSEKFWRENAVRLNEKNYELLKILTKLLEVSDDPQVLAVAAHDVGEYVR 419
           KSG LEWSPVHK+++FWRENA+RLNE NYELLKIL +LLE S D  VL+VAAHD+GEYVR
Sbjct: 465 KSGNLEWSPVHKTDRFWRENAMRLNEHNYELLKILVRLLETSRDALVLSVAAHDIGEYVR 286

Query: 420 HYPRGKRVIEQLGGKQLVMNHMHHEDQQVRYNALLAVQKLMVHNWEYLGKQLQSEQPQT 478
           +YPRGK +IEQLG KQ VM ++ HED  VRY AL+AVQKLMVHNWEYLG+++  +QP++
Sbjct: 285 YYPRGKNIIEQLGAKQRVMQYLTHEDPNVRYEALIAVQKLMVHNWEYLGRKMTEDQPKS 109
>26430
          Length = 404

 Score =  178 bits (452), Expect = 3e-45,   Method: Compositional matrix adjust.
 Identities = 82/134 (61%), Positives = 108/134 (80%)
 Frame = +3

Query: 252 FSPQMCEHLRRYNIIPVLSDILQESVKEKVTRIILAAFRNFLEKSTERETRQEYALAMIQ 311
           F+  + E + R N+IPVL+DIL  + +EKVTRI+LA FRN LEK  ER   QEYALA+++
Sbjct: 3   FNNALVERMNRMNLIPVLADILSSTQREKVTRIVLALFRNMLEKPAERSVTQEYALALVR 182

Query: 312 CKVLKQLENLEQQKYDDEDISEDIKFLLEKLGESVQDLSSFDEYSSELKSGRLEWSPVHK 371
           CKV+KQLE L+ +K++D D+ EDIK++  KL  SVQDLSSFDEY SE+KSG LEWSPVH+
Sbjct: 183 CKVVKQLELLDARKWEDPDLEEDIKWIAAKLESSVQDLSSFDEYVSEVKSGNLEWSPVHR 362

Query: 372 SEKFWRENAVRLNE 385
           +++FWRENA+RLN+
Sbjct: 363 TDRFWRENAIRLND 404
>33274
          Length = 574

 Score = 28.5 bits (62), Expect = 5.6,   Method: Compositional matrix adjust.
 Identities = 13/40 (32%), Positives = 22/40 (55%)
 Frame = -1

Query: 116 KRSKSTAWPYFLPMLNRQDPFTVHMAARIIAKLAAWGKEL 155
           K +KST+    +P L +  P  +HMA ++     AWG ++
Sbjct: 373 KVTKSTSMXPTMPRLLQASPTCLHMALKMAGSTDAWGTDI 254
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31981925|ref|NP_033562.2| tyrosine
3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
polypeptide [Mus musculus]
         (255 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

12344                                                                 412   e-116
13465                                                                 236   5e-63
33715                                                                 175   2e-44
17028                                                                 124   3e-29
15092                                                                 108   2e-24
27988                                                                  59   7e-16
18027                                                                  28   3.3  
01750                                                                  27   6.4  
>12344
          Length = 1658

 Score =  412 bits (1058), Expect = e-116,   Method: Compositional matrix adjust.
 Identities = 208/254 (81%), Positives = 224/254 (88%), Gaps = 1/254 (0%)
 Frame = +2

Query: 1   MDDREDLVYQAKLAEQAERYDEMVESMKKVAGMDVELTVEERNLLSVAYKNVIGARRASW 60
           M DRED VYQAK   +AERYDEMV+ MK VA MDVELTVEERNLLSVAYKNVIGARRASW
Sbjct: 56  MGDREDQVYQAKQLNRAERYDEMVKFMKIVACMDVELTVEERNLLSVAYKNVIGARRASW 235

Query: 61  RIISSIEQKEENKGGEDKLKMIREYRQMVETELKLICCDILDVQDKHLIPAANTGESKVF 120
           RI+SS+EQKE+    EDK  + +EYR  +E ELK IC D+LD+ +KHLI  ANTGESKVF
Sbjct: 236 RIVSSLEQKEDK--CEDKKAINKEYRMKIEKELKDICEDVLDILEKHLIVNANTGESKVF 409

Query: 121 YYKMKGDYHRYLAEFATGNDRKEAAENSLVAYKAASDIAMTELPPTHPIRLGLALNFSVF 180
           YYKMKGDYHRYLAEFA GNDRKEAAENSLVAYKAASDIAM EL PTHPIRLGLALNFSVF
Sbjct: 410 YYKMKGDYHRYLAEFAVGNDRKEAAENSLVAYKAASDIAMIELAPTHPIRLGLALNFSVF 589

Query: 181 YYEILNSPDRACRLAKAAFDDAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSDMQGD-G 239
           YYEILNSPDRACRLAKAAFDDAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSDMQG+ G
Sbjct: 590 YYEILNSPDRACRLAKAAFDDAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSDMQGEGG 769

Query: 240 EEQNKEALQDVEDE 253
           EEQ+ + +QD+E E
Sbjct: 770 EEQSTQQVQDIEGE 811
>13465
          Length = 596

 Score =  236 bits (603), Expect = 5e-63,   Method: Compositional matrix adjust.
 Identities = 116/153 (75%), Positives = 131/153 (85%)
 Frame = +2

Query: 1   MDDREDLVYQAKLAEQAERYDEMVESMKKVAGMDVELTVEERNLLSVAYKNVIGARRASW 60
           M DR+D VYQAKLAEQAERYDEMVE+MKKVA M  +LTVEERNLLSVAYKNVIGARRASW
Sbjct: 110 MTDRDDFVYQAKLAEQAERYDEMVEAMKKVASMGNDLTVEERNLLSVAYKNVIGARRASW 289

Query: 61  RIISSIEQKEENKGGEDKLKMIREYRQMVETELKLICCDILDVQDKHLIPAANTGESKVF 120
           RI+SS+EQK+ +K   DK KM + YRQ +ETELK IC D+L + D HLIP+   GESKVF
Sbjct: 290 RIVSSVEQKDLDKPDPDKGKMTKGYRQQIETELKQICEDVLKIIDDHLIPSTTQGESKVF 469

Query: 121 YYKMKGDYHRYLAEFATGNDRKEAAENSLVAYK 153
           YYKMKGDY+RYLAEFATG+ RKEAAE+SLVAYK
Sbjct: 470 YYKMKGDYYRYLAEFATGDPRKEAAESSLVAYK 568
>33715
          Length = 434

 Score =  175 bits (444), Expect = 2e-44,   Method: Compositional matrix adjust.
 Identities = 85/119 (71%), Positives = 95/119 (79%)
 Frame = -1

Query: 123 KMKGDYHRYLAEFATGNDRKEAAENSLVAYKAASDIAMTELPPTHPIRLGLALNFSVFYY 182
           KMKGDY+RYL+E + G  RKE    S+ AYK A+D+A   L  THPIRLGLALNFSVF+Y
Sbjct: 371 KMKGDYYRYLSEVSQGEQRKENVGKSMEAYKEATDMAKERLSSTHPIRLGLALNFSVFHY 192

Query: 183 EILNSPDRACRLAKAAFDDAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSDMQGDGEE 241
           EI N PD ACRLAK AFD+AI  LD L+EESYKDSTLIMQLLRDNLTLWTSD QG+G E
Sbjct: 191 EIKNCPDEACRLAKIAFDEAIQCLDQLNEESYKDSTLIMQLLRDNLTLWTSDSQGEGTE 15
>17028
          Length = 1078

 Score =  124 bits (312), Expect = 3e-29,   Method: Compositional matrix adjust.
 Identities = 63/105 (60%), Positives = 78/105 (74%), Gaps = 2/105 (1%)
 Frame = +1

Query: 142 KEAAENSLVAYKAASDIAMTELPPTHPIRLGLALNFSVFYYEILNSPDRACRLAKAAFDD 201
           +EA   +  AY  A ++A   + PTHP RLGLALN+SVFYYEILNS D+AC LAK AFD+
Sbjct: 28  QEAVTKAQEAYNKAMEVAKQSMAPTHPNRLGLALNYSVFYYEILNSQDKACDLAKTAFDE 207

Query: 202 AIAELDTLSE-ESYKDSTLIMQLLRDNLTLWTSDMQG-DGEEQNK 244
           AI E+D   E +  KDSTLIMQLLRDNLTLWTSD    +G++Q++
Sbjct: 208 AIQEMDQCGERDDCKDSTLIMQLLRDNLTLWTSDSNAENGDDQDR 342
>15092
          Length = 692

 Score =  108 bits (271), Expect = 2e-24,   Method: Compositional matrix adjust.
 Identities = 61/109 (55%), Positives = 77/109 (70%), Gaps = 8/109 (7%)
 Frame = +3

Query: 1   MDDREDLVYQAKLAEQAERYDEMVESMKKV------AGMDVELTV--EERNLLSVAYKNV 52
           +  +E  V+ AK+AEQAERYD+M ESM K       A  D   T+  EERNLLSVAYKNV
Sbjct: 222 LSPKERQVHAAKIAEQAERYDDMAESMHKCVVEGYSANGDKSSTLDNEERNLLSVAYKNV 401

Query: 53  IGARRASWRIISSIEQKEENKGGEDKLKMIREYRQMVETELKLICCDIL 101
           +GARR++WR+ISSIEQK EN   + KL+M ++YR+ VE ELK IC  +L
Sbjct: 402 VGARRSAWRVISSIEQKTEN--NDKKLEMAKKYREKVEKELKEICTQVL 542
>27988
          Length = 448

 Score = 58.9 bits (141), Expect(2) = 7e-16,   Method: Compositional matrix adjust.
 Identities = 30/60 (50%), Positives = 41/60 (68%)
 Frame = +3

Query: 44  LLSVAYKNVIGARRASWRIISSIEQKEENKGGEDKLKMIREYRQMVETELKLICCDILDV 103
           L SVAYKNV+GARR+SWR+I  IEQK E +  ++K    R +R+ VE EL   C ++L +
Sbjct: 276 LFSVAYKNVVGARRSSWRVICMIEQKAETQPRKEK---ARAFRKDVEKELDATCNEVLKL 446

 Score = 41.6 bits (96), Expect(2) = 7e-16,   Method: Compositional matrix adjust.
 Identities = 22/38 (57%), Positives = 27/38 (71%)
 Frame = +2

Query: 5   EDLVYQAKLAEQAERYDEMVESMKKVAGMDVELTVEER 42
           +DL+  AKLAEQAERYD+M ++MKKV   D  L  E R
Sbjct: 158 KDLISFAKLAEQAERYDDMAKAMKKVTENDKTLMQESR 271
>18027
          Length = 448

 Score = 28.1 bits (61), Expect = 3.3,   Method: Compositional matrix adjust.
 Identities = 13/39 (33%), Positives = 25/39 (64%)
 Frame = +1

Query: 211 EESYKDSTLIMQLLRDNLTLWTSDMQGDGEEQNKEALQD 249
           EE +  +T+ +Q + D L  WT  ++G+G E ++ A++D
Sbjct: 307 EEQFGKNTISLQYVPDLLACWTLHVRGEGGE-DRHAIED 420
>01750
          Length = 1886

 Score = 27.3 bits (59), Expect = 6.4,   Method: Compositional matrix adjust.
 Identities = 24/79 (30%), Positives = 40/79 (50%), Gaps = 2/79 (2%)
 Frame = +2

Query: 20  YDEMVESMKKVAGMDVELT--VEERNLLSVAYKNVIGARRASWRIISSIEQKEENKGGED 77
           Y E  E+  K A  DV +   V ++N     YK V+ AR   W++  SIE+    K  ED
Sbjct: 440 YKEKGETPPKRA-FDVAVKEWVVQQNSNRPVYKTVV-ARPVDWKV-PSIERMWLGKSDED 610

Query: 78  KLKMIREYRQMVETELKLI 96
           K + +R +  ++ ++  L+
Sbjct: 611 KNRRLRAFLTIMHSDSNLV 667
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|55741703|ref|NP_598555.1| glutaminyl-tRNA synthetase
[Mus musculus]
         (775 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

05674                                                                 416   e-116
16782                                                                  30   2.9  
>05674
          Length = 1437

 Score =  416 bits (1069), Expect = e-116,   Method: Compositional matrix adjust.
 Identities = 200/292 (68%), Positives = 235/292 (80%)
 Frame = -1

Query: 483  EYGRLNLHYAVVSKRKILQLVAAGAVRDWDDPRLFTLTALRRRGFPPEAINNFCARVGVT 542
            EYGRLNLHYAVVSKRKI +L+  G VR+WDDPRLFTLTALRRRGFP EAIN FCA+VGVT
Sbjct: 1437 EYGRLNLHYAVVSKRKIGKLITEGFVRNWDDPRLFTLTALRRRGFPSEAINYFCAKVGVT 1258

Query: 543  VAQTTMEPHLLEACVRDVLNDAAPRAMAVLEPLQVVITNFPAPKPLDIRVPNFPADETKG 602
            +A+T ++P +LEACVR+VLN  APRAMAVL+PL+VVI NFPA    ++ VPNFPADE+KG
Sbjct: 1257 MAKTVIDPVMLEACVREVLNVKAPRAMAVLDPLKVVIQNFPADHSGEVTVPNFPADESKG 1078

Query: 603  FHQVPFASTVFIERSDFKEESEPGYKRLASGQPVGLRHTGYVIELQNIVRGSSGCVERLE 662
             H+VP  S +FIERSDF+EE++  YKRLA  Q VGLRH G VI ++++V+ + G V  L 
Sbjct: 1077 SHKVPLTSIIFIERSDFREEADKNYKRLAVNQTVGLRHAGLVISVESVVKDADGQVAELV 898

Query: 663  VTCRRADAGEKPKAFIHWVSQPLVCEIRLYERLFQHKNPEDPVEVPGGFLSDLNPASLQV 722
            V C  A    KPKAFIHWVSQPL CEIRLY+ LF HKNPEDP EVPGGFL+D+N  SL V
Sbjct: 897  VKCVNATETSKPKAFIHWVSQPLHCEIRLYDTLFYHKNPEDPSEVPGGFLTDVNKDSLTV 718

Query: 723  VEGALVDCSVALAKPFDKFQFERLGYFSVDPDSHQGQIVFNRTVTLKEDPGK 774
            +  ALVD SV+ AK +DKFQFER G+FSVDPDS   ++VFNRTVTLKEDPGK
Sbjct: 717  LRTALVDNSVSGAKTYDKFQFERNGFFSVDPDSSPDKLVFNRTVTLKEDPGK 562
>16782
          Length = 454

 Score = 30.4 bits (67), Expect = 2.9,   Method: Composition-based stats.
 Identities = 13/25 (52%), Positives = 15/25 (60%)
 Frame = -3

Query: 433 CIYPTYDYTHCLCDSIEHITHSLCT 457
           CIY    + HC+C  I   THSLCT
Sbjct: 140 CIY-VDKHKHCMCTCIAAHTHSLCT 69
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31981106|ref|NP_065644.2| mannosyl-oligosaccharide
glucosidase [Mus musculus]
         (834 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

14764                                                                 290   e-115
36956                                                                  30   3.2  
09941                                                                  29   7.6  
>14764
          Length = 2105

 Score =  290 bits (743), Expect(2) = e-115,   Method: Compositional matrix adjust.
 Identities = 153/331 (46%), Positives = 204/331 (61%), Gaps = 19/331 (5%)
 Frame = -3

Query: 378  KGLSPEEQALGQVALSGLLGGIGYFYGQGLVLPDTSMEGSEQKMDPALFPPVPLFSGVPS 437
            +G+  +E  + + A+S +LG IGYFYG  LV        S+   +P  +   PLFS VPS
Sbjct: 1680 RGMERKESRVAKAAMSNMLGSIGYFYGSSLV-------QSQYNKEPVDYWEAPLFSAVPS 1522

Query: 438  RSFFPRGFLWDEGFHQLVVQRWDPHLTREALGHWLGLLNADGWIGREQILGDEARARVPP 497
            R FFPRGFLWDEGFH L++ RWD  L+ E +GHWL L+N +GWI REQILG EARA+VP 
Sbjct: 1521 RPFFPRGFLWDEGFHNLLISRWDEDLSLEIIGHWLDLMNTEGWIPREQILGVEARAKVPS 1342

Query: 498  EFLVQRAAHANPPTLLLP---VVHMLEGH-DPDDLAFLRKAFPRLHAWFSWLHQSQAGPV 553
            EF+VQR  +ANPPT  LP   ++H + G   P +  +L   +PRL  W++W + SQ G V
Sbjct: 1341 EFVVQRNKNANPPTFFLPLKRLIHKMVGSGSPAEHRYLENLYPRLKTWYAWYNTSQVGSV 1162

Query: 554  PLSYRWRGRDLALPTLLNPKTLPSGLDDYPRASHPSTAERHLDLRCWVALGARVLSQLAE 613
              +YRWRGRD      LNP TL SGLDD PRASHPS  ERH+DLRCW+AL + V++++A+
Sbjct: 1161 GSTYRWRGRDAKTVNQLNPLTLTSGLDDXPRASHPSDEERHVDLRCWMALASGVMAEIAK 982

Query: 614  QLG----ETEAAAELGPLAASLEEPGSLDELHWAPELGVFADFGNHTKAVQLKSRPPQGL 669
             L     E +A   L      L +   LD LHW+ +   ++D+G H+  V+L+  PP   
Sbjct: 981  SLNKEWQEYDATYRL------LTDNALLDSLHWSEKGQQYSDYGRHSDRVKLEKPPPPAH 820

Query: 670  VRVVGRPP-----------PRLQYVDALGYV 689
            ++   RPP           P+ QYV+A GYV
Sbjct: 819  LQPGQRPPDLPKVRVSLTEPKDQYVNAFGYV 727

 Score =  145 bits (367), Expect(2) = e-115,   Method: Compositional matrix adjust.
 Identities = 62/126 (49%), Positives = 91/126 (72%)
 Frame = -1

Query: 709 LLDVLADSRHLWSPFGLRSLSASSLFYKQRNTEHDPPYWRGAVWLNINYLALGALHHYGH 768
           +L  L D   LW+ +GLRSL+  +  Y + NTEHDPPYWRG +W+N+NYL+L AL+HY H
Sbjct: 668 VLTDLKDPSLLWTEYGLRSLARMNRMYNRYNTEHDPPYWRGPIWINMNYLSLSALYHYAH 489

Query: 769 VEGPHKVQAAKLYHELRANVVRNVRQQYQATGFLWEQYSDQDGRGMGCRPFQGWTSLVLL 828
             G +   A ++Y +LRAN+V+N+ ++++ TG++WE YSD+ G G G  PF GW++L++L
Sbjct: 488 TPGSYSQLAGEIYSDLRANLVKNMVKEFERTGYIWENYSDKTGEGKGSHPFTGWSALLVL 309

Query: 829 IMAEEY 834
           IM E Y
Sbjct: 308 IMGEIY 291

 Score = 62.0 bits (149), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 53/167 (31%), Positives = 75/167 (44%), Gaps = 3/167 (1%)
 Frame = -2

Query: 226  LKSISGHTSELGDFRLTLLPPTSPGDTVPKHGSYNVFWSSNPGLPQLTDMVKS--RLNSW 283
            L  ++GH+ ELG F L      +    V    +Y       P L QLTD+V++  R+ +W
Sbjct: 2089 LNKVTGHSQELGAFTLRFPKVKAESQKVAHLVTYA------PNLAQLTDVVRAGMRVEAW 1928

Query: 284  FQHRP-PGASPDRYLGLPGSLKWEERGPSGQGQFLIQQVTLKAPFSVEFVFESGSAATGG 342
             + R  P      Y  L G L  ++  P      +++QVT   P  +E VFESGS     
Sbjct: 1927 DKARTLP------YFTLGGRLVPKD-APGAN--LIVKQVTATLPMEMEVVFESGSVQDRP 1775

Query: 343  NQASGRLVGSQLTQALESHAAAFKERFEKTFQLKEKGLSPEEQALGQ 389
            N     L G+    AL SH   F ++F   FQL +KG   +    GQ
Sbjct: 1774 NA----LEGAVFNDALRSHIDDFNQKFNGIFQLDQKGYGEKRIPSGQ 1646
>36956
          Length = 460

 Score = 30.4 bits (67), Expect = 3.2,   Method: Composition-based stats.
 Identities = 16/60 (26%), Positives = 25/60 (41%)
 Frame = +1

Query: 250 GDTVPKHGSYNVFWSSNPGLPQLTDMVKSRLNSWFQHRPPGASPDRYLGLPGSLKWEERG 309
            D  P +  Y ++  ++  +    +M  +R + W   R      DRYL     LKW E G
Sbjct: 85  ADQYPSNSMYMIWTRADQYIGHNKNMXWTRADHWTDXRXEXIXTDRYLVTNMELKWTETG 264
>09941
          Length = 435

 Score = 29.3 bits (64), Expect = 7.6,   Method: Composition-based stats.
 Identities = 13/28 (46%), Positives = 17/28 (60%)
 Frame = +3

Query: 729 SASSLFYKQRNTEHDPPYWRGAVWLNIN 756
           SA+ L +K R TEH  P ++   WL IN
Sbjct: 270 SAAKLIFKARKTEHCTPLFKQLHWLPIN 353
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|46048300|ref|NP_705776.2| hypothetical protein
LOC223593 [Mus musculus]
         (1159 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

17766                                                                 411   e-115
12447                                                                 248   1e-65
10280                                                                  83   5e-16
>17766
          Length = 940

 Score =  411 bits (1056), Expect = e-115,   Method: Compositional matrix adjust.
 Identities = 188/307 (61%), Positives = 240/307 (78%)
 Frame = -3

Query: 754  SFEYIQDYVSIYGLKIWQEEVSRIINYNVEQECNNFLRTKIQDWQSMYQSTHIPIPKFAP 813
            SFEYIQDYV+IYGLKIWQEEVSRIINYNVEQECN+FLRTK+QDWQS+YQST IPIPKF  
Sbjct: 932  SFEYIQDYVNIYGLKIWQEEVSRIINYNVEQECNSFLRTKVQDWQSIYQSTAIPIPKFQM 753

Query: 814  VDESITFIGRLCREILRITDPKMTCYIDQLNTWYDVKTHQEVTSSRLFSEIQTTLGTFGL 873
            VDES+ FIGRL REI+RITDPK T YIDQ+  WYD+KT  E+ + +LF +I   +G+FGL
Sbjct: 752  VDESVNFIGRLAREIIRITDPKTTTYIDQMKAWYDLKTKAEICNRKLFEKIHRAVGSFGL 573

Query: 874  NGLDRLLCFMIVKELQNFLSMFQKIILKERTVQETLKMLMSAVNPLKSIVANSSKVYLSA 933
            +GLDRLLCFM+V+ELQNF  + Q+ +LK++   +    L   +NPL+ +VA   KVY  A
Sbjct: 572  SGLDRLLCFMVVRELQNFQRLMQRQVLKDKNWSDFFMQLTRTLNPLQGLVAQPQKVYPQA 393

Query: 934  ITKTQKIWSAYLEAIMKVGQMQILRQQIANELNSSCRFDSRHXXXXXXXXXXXXXXXIEA 993
            I+KT ++W+ +++ I+ VGQ+Q+LR+QIA ELN+SC+FDS+                IE 
Sbjct: 392  ISKTSRLWTHFVDIILXVGQLQLLRRQIAYELNTSCKFDSKFLASSLQTFNNGLLADIER 213

Query: 994  HYRDPSLPYPKEDNTLLYEITAYLEAAGIHNPLNKIYITTKRLPYFPIVNFLFLIAQLPK 1053
            HY+DPSLPYPKE+N LL+E+TAYLE+AG HNPL KIYITT+R+P F + NFLF ++QLPK
Sbjct: 212  HYQDPSLPYPKEENPLLFELTAYLESAGFHNPLMKIYITTQRMPMFALFNFLFTLSQLPK 33

Query: 1054 LQYNKNL 1060
            L YNK++
Sbjct: 32   LVYNKSI 12
>12447
          Length = 456

 Score =  248 bits (632), Expect = 1e-65,   Method: Compositional matrix adjust.
 Identities = 111/140 (79%), Positives = 126/140 (90%)
 Frame = +2

Query: 180 DSNMDDICKLLRSTGYSSQPGAKRPPNYPESYFQRVPINETFISMVIGRLRSDDIYNQVS 239
           DSN+DD+CKLLRSTG+S+ P AKRPPNYPE++F RVPIN  +++MVIGRLRSDD+YNQ+S
Sbjct: 2   DSNIDDVCKLLRSTGFSTAPNAKRPPNYPEAFFSRVPINAEYVNMVIGRLRSDDVYNQIS 181

Query: 240 AYPLPEHRSTALANQAAMLYVILYFEPSILHTHQAKMREIVDKYFPDNWVISIYMGITVN 299
           AYP PEHRSTALA QA+MLYVILYFEP IL   QAKMREIVDK+FPDNWVIS+YMG TVN
Sbjct: 182 AYPQPEHRSTALATQASMLYVILYFEPDILLNQQAKMREIVDKHFPDNWVISVYMGTTVN 361

Query: 300 LADAWEPYKAAKTALNNTLD 319
           L DAW+PYKAA TALNNTLD
Sbjct: 362 LLDAWQPYKAALTALNNTLD 421
>10280
          Length = 2352

 Score = 83.2 bits (204), Expect = 5e-16,   Method: Compositional matrix adjust.
 Identities = 37/90 (41%), Positives = 56/90 (62%)
 Frame = +2

Query: 1068 ADPVDWPPXXXXXXXXXKQFHSRYTEQFLALIGQFIRSTMEQCTSQKMPEMPADAVGALL 1127
            ADP+D PP         KQFHS  T  FLA + Q++RS ++   S K+ E P D +  L+
Sbjct: 5    ADPLDAPPLVVGIFTLLKQFHSENTHFFLAFLAQYVRSIVDTMASAKLAEGPQDVLNVLV 184

Query: 1128 FLEDYVRYTKLPRRVAEAHVPNFIFDEFRT 1157
            FLE+++ Y+ LPR++ E+ +P +I DE R+
Sbjct: 185  FLENFIFYSGLPRKMLESLLPAYILDECRS 274
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|117320529|ref|NP_001028442.2| solute carrier family
4, sodium bicarbonate cotransporter, member 7 [Mus musculus]
         (1131 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

14939                                                                 217   e-114
17976                                                                 182   2e-54
18083                                                                 120   4e-27
07825                                                                  33   0.61 
26881                                                                  33   0.75 
25382                                                                  29   9.1  
>14939
          Length = 1186

 Score =  217 bits (552), Expect(2) = e-114,   Method: Compositional matrix adjust.
 Identities = 99/150 (66%), Positives = 117/150 (78%)
 Frame = -1

Query: 732  FPTKVRSTISDFAVFLTIVIMVAIDYLVGIPSPKLHVPEKFEPTDPSRGWIISPLGDNPW 791
            FPT VR+T+SDF+V + I+ MV  D  VG+P+PKLHVPE F PT+P RGW+I+P+G+NPW
Sbjct: 1114 FPTMVRATLSDFSVLIAILSMVVFDICVGLPTPKLHVPETFAPTNPKRGWLINPVGENPW 935

Query: 792  WTLLIAAVPALLCTILIFMDQQITAVIINRKEHKLKKGAGYHLDXXXXXXXXXXCSIMGL 851
            WT L A +PALL  ILIFMDQQITAVI+NRKE+KL KG GYHLD          CS +GL
Sbjct: 934  WTTLAAVIPALLAVILIFMDQQITAVIVNRKENKLVKGRGYHLDLFIVSVLIILCSFLGL 755

Query: 852  PWFVAATVLSISHVNSLKVESECSAPGEQP 881
            PWFVAATVLSI+HVNSLK ES+CSAP   P
Sbjct: 754  PWFVAATVLSINHVNSLKKESQCSAPANNP 665

 Score =  213 bits (542), Expect(2) = e-114,   Method: Compositional matrix adjust.
 Identities = 110/225 (48%), Positives = 155/225 (68%), Gaps = 1/225 (0%)
 Frame = -3

Query: 876  APGEQPKFLGIREQRVTGLMIFILMGLSVFMTSVLKFIPMPVLYGVFLYMGVSSLKGIQF 935
             PGEQPKFLG+REQRVTG+ IF+L+G+SV +TSVLKFIPMPVLYGVFLYMGVSSL+G+Q 
Sbjct: 683  CPGEQPKFLGVREQRVTGITIFLLIGISVMLTSVLKFIPMPVLYGVFLYMGVSSLRGMQL 504

Query: 936  FDRIKLFGMPAKHQPDLIYLRYVPLWKVHVFTVVQLTCLVLLWVIKA-SAAAVVFPMMVL 994
              R+ ++ MPAK+Q DL++LR+V   +VH+FT++Q+ CL+ LW IK+    ++ FP+MVL
Sbjct: 503  VHRVLIWFMPAKYQWDLMFLRHVRTNRVHLFTIIQIFCLLCLWGIKSYKKISIAFPIMVL 324

Query: 995  ALVFVRKLMDLCFTKRELSWLDDLMPESXXXXXXXXXXXXXXXAERMLQDDEDTVHLPFE 1054
            A+ FVRK +D  F +REL WLDD+MPE+                E+     E +  +P  
Sbjct: 323  AMCFVRKALDWVFDQRELKWLDDIMPEA---HKRAKEDEIKKQEEQRFSLIEGSTSIPLA 153

Query: 1055 RGSLLQIPVKTLKYSIDPSVVNISDEMAKTAQWKALSMNTENAKV 1099
             G  L +   T++  +D   VNIS+EM++TA WK++  N  ++ +
Sbjct: 152  MG--LNMEHITIQAEMDQ--VNISEEMSRTALWKSIMHNESSSNL 30
>17976
          Length = 781

 Score =  182 bits (463), Expect(2) = 2e-54,   Method: Compositional matrix adjust.
 Identities = 83/139 (59%), Positives = 112/139 (80%), Gaps = 1/139 (0%)
 Frame = +1

Query: 885  GIREQRVTGLMIFILMGLSVFMTSVLKFIPMPVLYGVFLYMGVSSLKGIQFFDRIKLFGM 944
            G+REQR+TGLM+ +L GL+V  T+VLKFIPM VLYGVFLYMG+++LKG+QF DRI L   
Sbjct: 139  GVREQRLTGLMVGLLSGLTVLFTAVLKFIPMAVLYGVFLYMGMAALKGMQFIDRILLMLK 318

Query: 945  PAKHQPDLIYLRYVPLWKVHVFTVVQLTCLVLLWVIKA-SAAAVVFPMMVLALVFVRKLM 1003
            PAK+QPD  YLR+VP+ +VH+FT +Q+ CL +LWVIK+  + +++FP+MVL   FVRK +
Sbjct: 319  PAKYQPDTTYLRHVPIKRVHIFTAIQVVCLAVLWVIKSVKSVSIIFPIMVLGTCFVRKGL 498

Query: 1004 DLCFTKRELSWLDDLMPES 1022
            D  FT+ EL WLDD+MP++
Sbjct: 499  DYLFTQGELKWLDDIMPDA 555

 Score = 49.7 bits (117), Expect(2) = 2e-54,   Method: Composition-based stats.
 Identities = 24/37 (64%), Positives = 30/37 (81%), Gaps = 1/37 (2%)
 Frame = +3

Query: 850 GLPW-FVAATVLSISHVNSLKVESECSAPGEQPKFLG 885
           GLP   VAATV +++H+ SLK ESEC+APGE+P FLG
Sbjct: 30  GLPLGTVAATVSALAHIMSLKKESECTAPGERPTFLG 140
>18083
          Length = 865

 Score =  120 bits (300), Expect = 4e-27,   Method: Composition-based stats.
 Identities = 74/202 (36%), Positives = 114/202 (56%), Gaps = 4/202 (1%)
 Frame = -3

Query: 806  ILIFMDQQITAVIINRKEHKLKKGAGYHLDXXXXXXXXXXCSIMGLPWFVAATVLSISHV 865
            +L FMDQ I+A ++N  ++K+KKG  YH D           S+   P   AA   S  HV
Sbjct: 863  LLFFMDQNISAALVNAPQNKMKKGTAYHWDLLVIAVVNAVISVFAFPMVHAALPHSPLHV 684

Query: 866  NSLKVESECSAPGEQPK-FLGIREQRVTGLMIFILMGLSVFMTSVLKFIPMPVLYGVFLY 924
             +L    E    G   +  + +RE R+T ++  IL+GLS+ +  VL +IP PVLYG+FLY
Sbjct: 683  RALADVEERVVQGHITQTVVRVRETRITAILSHILIGLSILIMFVLAYIPTPVLYGLFLY 504

Query: 925  MGVSSLKGIQFFDRIKLFGMPAKHQPDLIYLRYVPLWKVHVFTVVQLTCLVLLWVIKASA 984
            + +++L   Q F+RI LF       P   Y+R+VP  KVH+FT++QL  LV+L V    +
Sbjct: 503  VAITALYDNQMFERITLFFTEQSAYPPTHYIRHVPQRKVHIFTLIQLLQLVVLCVFGFVS 324

Query: 985  AA---VVFPMMVLALVFVRKLM 1003
             A   + FP+++  L+ +R ++
Sbjct: 323  FAYLKMFFPVLIFLLIPIRHMV 258
>07825
          Length = 1413

 Score = 33.1 bits (74), Expect = 0.61,   Method: Composition-based stats.
 Identities = 19/65 (29%), Positives = 33/65 (50%)
 Frame = +1

Query: 553 LVFEKILFKFCRDYHLSYLSLRTSIGLWTSFLCIVLVATDASSLVCYITRFTEEAFAALI 612
           L+F   LF+ CR+  L  L LR +      FLCI      + SLV ++    +E+   ++
Sbjct: 133 LLFMSFLFQECREGALMILFLRKTWAFLLYFLCI-----SSLSLVIFVFGQQQESSKQIL 297

Query: 613 CIIFI 617
           C++ +
Sbjct: 298 CVVLL 312
>26881
          Length = 448

 Score = 32.7 bits (73), Expect = 0.75,   Method: Compositional matrix adjust.
 Identities = 21/52 (40%), Positives = 26/52 (50%)
 Frame = +2

Query: 513 EATEGRISAIESLFGASLTGIAYSLFAGQPLTILGSTGPVLVFEKILFKFCR 564
           E+   RI+ +E  FG+S          GQPL I    G VLV E +L K CR
Sbjct: 50  ESNARRINFVEQCFGSS----------GQPLAI---AGRVLVGEGVLTKLCR 166
>25382
          Length = 989

 Score = 29.3 bits (64), Expect = 9.1,   Method: Composition-based stats.
 Identities = 19/50 (38%), Positives = 25/50 (50%), Gaps = 6/50 (12%)
 Frame = +1

Query: 552 VLVFEKILFK------FCRDYHLSYLSLRTSIGLWTSFLCIVLVATDASS 595
           VL F  + F       FC +Y+   L L  +  L T FLC+VLV  D S+
Sbjct: 829 VLCFSVLCFSVLCVSLFCVEYY*K*LFLCINCKLLTPFLCLVLVIVDMSN 978
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|149265148|ref|XP_995248.2| PREDICTED: filamin B, beta
isoform 6 [Mus musculus]
         (2619 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

13043                                                                 410   e-114
16231                                                                 245   6e-74
17351                                                                 234   3e-61
29446                                                                 202   2e-51
19277                                                                 157   7e-44
21436                                                                 149   1e-35
27230                                                                  74   4e-21
19002                                                                  95   4e-19
05081                                                                  84   7e-16
19147                                                                  65   4e-10
19154                                                                  64   9e-10
29755                                                                  62   3e-09
09100                                                                  53   1e-06
17613                                                                  53   2e-06
35059                                                                  50   2e-05
09711                                                                  48   6e-05
04951                                                                  46   2e-04
18202                                                                  41   0.007
32088                                                                  37   0.091
31031                                                                  35   0.35 
>13043
          Length = 1574

 Score =  410 bits (1055), Expect = e-114,   Method: Compositional matrix adjust.
 Identities = 234/539 (43%), Positives = 315/539 (58%), Gaps = 2/539 (0%)
 Frame = +3

Query: 1357 GIGGLGITVEGPSESKINCRDNKDGSCSAEYIPFAPGDYDVNITYGGVHIPGSPFRVPSK 1416
            G GGLG+ +EGP E+K+ C DN+DG+C  EY P  PG YD+++ +G   I  SPF V  +
Sbjct: 3    GKGGLGLGIEGPVEAKMKCDDNRDGTCRVEYYPTKPGKYDISVLFGDKPIKDSPFSVKIQ 182

Query: 1417 DVVDPSKVKIAGPGL-SSCVRACIPQSFTVDSSKAGLAPLEVRVLGP-RGLVEPVNVVDN 1474
            + VD SKVK  GPGL +S V A +P  FTVD+  AG APL+V    P  G  +   +V  
Sbjct: 183  NPVDASKVKCYGPGLDASEVAANLPAVFTVDARDAGEAPLDVTFTDPLSGAQQEAEIVPV 362

Query: 1475 GDGTHTVTYTPSQEGPYIVSVKYADEEIPRSPFKVKVLPTYDASKVTASGPGLSAYGVPA 1534
             +G +  TY P  EG   V VKY  + +P SPF ++VLP  D SKV  SGPG+    VPA
Sbjct: 363  EEGLYQATYMPRAEGKCKVDVKYGGKPVPNSPFHMQVLPGVDPSKVKVSGPGVRR-SVPA 539

Query: 1535 SLPVEFAIDARDAGEGLLAVQITDQEGKPQRATVHDNKDGTYAVTYIPDKTGRYMIGVTY 1594
            SLP +F +D RDAG   L   +   +G   +    +N+DGTY V Y P+  G Y I V Y
Sbjct: 540  SLPAQFTVDTRDAGVADLECMVQRPDGSFIKPYFQNNEDGTYDVIYTPEDLGVYDIIVKY 719

Query: 1595 GGDNIPLSPYRIRATQTGDASKCLATGPGIAPTVKTGEEVGFVVDAKTAGKGKVTCVILT 1654
             G ++P SP+ + AT  GDAS+C  T  G    +   +E    VDA  AGKG VTC I +
Sbjct: 720  DGQDVPRSPFNVEATPLGDASQCRITD-GAERVIPIEKETVITVDAADAGKGSVTCRIRS 896

Query: 1655 PDGTEAEADVIENEDGTYDIFYTAAKPGTYVIYVRFGGVDIPNSPFTVMVSRVPSPEPAL 1714
            P G++ + D+++  DGT+ I +     G Y+I ++FGG  +P+  +T         E  L
Sbjct: 897  PSGSDIDIDIVDQGDGTFTISFIPQYAGEYIIEIKFGGNFVPDGQYTAEAVPEDEYEKYL 1076

Query: 1715 TSRSTSTCWKLGEGRAQAVGSWVTEEAYVPVSDMNGLGFKPFDLVIPFAVRKGEITGTVH 1774
             SR               V   V +    P S +    ++P D   P       ++ +V 
Sbjct: 1077 QSRVVDDLI---------VADQVDQVNAAPGSGL----YQPVDFQFPVGPIFNFVSASVI 1217

Query: 1775 MPSGKKATPEIVDNKDGTVTVRYAPTEVGLHEMHIKYRGSHIPGNPLQFYVNYPNSGSVS 1834
            MPSGK + P+I DN+DGTVTVRY PTE GLHE+H+KY    I G+P  F+V+  NSG V+
Sbjct: 1218 MPSGKTSYPKIEDNRDGTVTVRYQPTETGLHELHVKYNNECIQGSPFFFHVDSVNSGYVT 1397

Query: 1835 AYGPGLVYGVANKTATFTIVTEDAGEGGLDLAIEGPSKAEISCIDNKDGTCTVTYLPTL 1893
            AYGPGL +GV  + A FTI T++AG GGL LA+EGPSK EI C+DN+DGTC V+YLP++
Sbjct: 1398 AYGPGLSHGVVYEPAVFTINTKEAGAGGLALAVEGPSKTEIKCVDNQDGTCNVSYLPSV 1574

 Score =  243 bits (619), Expect = 1e-63,   Method: Compositional matrix adjust.
 Identities = 174/536 (32%), Positives = 261/536 (48%), Gaps = 13/536 (2%)
 Frame = +3

Query: 580  GTLGFAIEGPSQAKIEYDDQNDGSCDVKYWPKEPGEYAVHIMCDDEDIKDSPYMAFIHPA 639
            G LG  IEGP +AK++ DD  DG+C V+Y+P +PG+Y + ++  D+ IKDSP+   I   
Sbjct: 9    GGLGLGIEGPVEAKMKCDDNRDGTCRVEYYPTKPGKYDISVLFGDKPIKDSPFSVKIQNP 188

Query: 640  TGDYNPDLVQAYGPGLEKSGCTINNPAEFIVDPKDAGSAPLKILAQDG-EGQPIDIQMKS 698
                +   V+ YGPGL+ S    N PA F VD +DAG APL +   D   G   + ++  
Sbjct: 189  V---DASKVKCYGPGLDASEVAANLPAVFTVDARDAGEAPLDVTFTDPLSGAQQEAEIVP 359

Query: 699  RMDGTYACSYTPLKAIKHTIAVVWGGVNIPHSPYRVNIGQGSHPQKVKVFGPGVERSGLK 758
              +G Y  +Y P    K  + V +GG  +P+SP+ + +  G  P KVKV GPGV RS + 
Sbjct: 360  VEEGLYQATYMPRAEGKCKVDVKYGGKPVPNSPFHMQVLPGVDPSKVKVSGPGVRRS-VP 536

Query: 759  ANEPTHFTVDCTEAGEGDVSVGIKCDARVLSDDEEDVDFDIIHNANDTFTVKYVPPAPGR 818
            A+ P  FTVD  +AG  D+      +  V   D   +     +N + T+ V Y P   G 
Sbjct: 537  ASLPAQFTVDTRDAGVADL------ECMVQRPDGSFIKPYFQNNEDGTYDVIYTPEDLGV 698

Query: 819  YTIKVLFASQEIPASPFRVKVDPSHDASKVKAEGPGLSKAGVENGKPTHFTVHTKGAGKA 878
            Y I V +  Q++P SPF V+  P  DAS+ +          +E  K T  TV    AGK 
Sbjct: 699  YDIIVKYDGQDVPRSPFNVEATPLGDASQCRITDGAERVIPIE--KETVITVDAADAGKG 872

Query: 879  PLNVQFSSPLPGEAVKDLDIIDNYDYSHTVKYTPTQQGNMQVLVTYGGDPIPKSPFTVGV 938
             +  +  SP   +   D+DI+D  D + T+ + P   G   + + +GG+ +P   +T   
Sbjct: 873  SVTCRIRSPSGSDI--DIDIVDQGDGTFTISFIPQYAGEYIIEIKFGGNFVPDGQYTAEA 1046

Query: 939  AAPLDLSKIKINGLENRVEVGKDQEFAIDTNGAGGQGKLDVTI-LSPSRKVVPCLVAPVA 997
                +  K   + + + + V    +      G+G    +D    + P    V   V   +
Sbjct: 1047 VPEDEYEKYLQSRVVDDLIVADQVDQVNAAPGSGLYQPVDFQFPVGPIFNFVSASVIMPS 1226

Query: 998  GRECS-----------TAKFIPREEGLFAVDVTYDGHPVPGSPYTVEASLPPDPTKVKAH 1046
            G+              T ++ P E GL  + V Y+   + GSP+        +   V A+
Sbjct: 1227 GKTSYPKIEDNRDGTVTVRYQPTETGLHELHVKYNNECIQGSPFFFHVD-SVNSGYVTAY 1403

Query: 1047 GPGLEGGLVGKPAEFTIDTKXXXXXXXXXXVEGPCEAKIECSDNGDGTCSVSYLPT 1102
            GPGL  G+V +PA FTI+TK          VEGP + +I+C DN DGTC+VSYLP+
Sbjct: 1404 GPGLSHGVVYEPAVFTINTKEAGAGGLALAVEGPSKTEIKCVDNQDGTCNVSYLPS 1571

 Score =  234 bits (596), Expect = 4e-61,   Method: Compositional matrix adjust.
 Identities = 185/532 (34%), Positives = 263/532 (49%), Gaps = 26/532 (4%)
 Frame = +3

Query: 1077 VEGPCEAKIECSDNGDGTCSVSYLPTKPGEYFVNILFEEVHIPGSPFKADIEMPFDPSKV 1136
            +EGP EAK++C DN DGTC V Y PTKPG+Y +++LF +  I  SPF   I+ P D SKV
Sbjct: 27   IEGPVEAKMKCDDNRDGTCRVEYYPTKPGKYDISVLFGDKPIKDSPFSVKIQNPVDASKV 206

Query: 1137 VASGPGLEHGKVGE--PGILCVDCSEAGPGTLGLEAVSD-SGAKAEVSIQNNKDGTYAVT 1193
               GPGL+  +V    P +  VD  +AG   L +      SGA+ E  I   ++G Y  T
Sbjct: 207  KCYGPGLDASEVAANLPAVFTVDARDAGEAPLDVTFTDPLSGAQQEAEIVPVEEGLYQAT 386

Query: 1194 YVPLTAGMYTLTMKYGGELVPHFPAWVKVEPAIDTSGIKAFGPGIEGKDVFREATTDFTV 1253
            Y+P   G   + +KYGG+ VP+ P  ++V P +D S +K  GPG+  + V       FTV
Sbjct: 387  YMPRAEGKCKVDVKYGGKPVPNSPFHMQVLPGVDPSKVKVSGPGVR-RSVPASLPAQFTV 563

Query: 1254 DSRPLTQVGGDHIKAQITNPSGASTECFVKDNADGTYQVEYTPFEKGFHVVEVTYDDVPI 1313
            D+R     G   ++  +  P G+  + + ++N DGTY V YTP + G + + V YD   +
Sbjct: 564  DTR---DAGVADLECMVQRPDGSFIKPYFQNNEDGTYDVIYTPEDLGVYDIIVKYDGQDV 734

Query: 1314 PNSPFKVAVTEGCQPSRVHAQGPGLKEAFTNKSNVFTVVTRGAGIGGLGITVEGPSESKI 1373
            P SPF V  T     S+        +     K  V TV    AG G +   +  PS S I
Sbjct: 735  PRSPFNVEATPLGDASQCRITDGAERVIPIEKETVITVDAADAGKGSVTCRIRSPSGSDI 914

Query: 1374 NCR--DNKDGSCSAEYIPFAPGDYDVNITYGGVHIPGSPFR---VPSKD--------VVD 1420
            +    D  DG+ +  +IP   G+Y + I +GG  +P   +    VP  +        VVD
Sbjct: 915  DIDIVDQGDGTFTISFIPQYAGEYIIEIKFGGNFVPDGQYTAEAVPEDEYEKYLQSRVVD 1094

Query: 1421 P-------SKVKIA-GPGLSSCVRACIPQSFTVDSSKAGLAPLEVRVLGPRGLVEPVNVV 1472
                     +V  A G GL   V    P     +   A        V+ P G      + 
Sbjct: 1095 DLIVADQVDQVNAAPGSGLYQPVDFQFPVGPIFNFVSA-------SVIMPSGKTSYPKIE 1253

Query: 1473 DNGDGTHTVTYTPSQEGPYIVSVKYADEEIPRSPFKVKVLPTYDASKVTASGPGLSAYGV 1532
            DN DGT TV Y P++ G + + VKY +E I  SPF   V  + ++  VTA GPGLS +GV
Sbjct: 1254 DNRDGTVTVRYQPTETGLHELHVKYNNECIQGSPFFFHV-DSVNSGYVTAYGPGLS-HGV 1427

Query: 1533 PASLPVEFAIDARDAGEGLLAVQITDQEGKPQRATVH--DNKDGTYAVTYIP 1582
                P  F I+ ++AG G LA+ +   EG P +  +   DN+DGT  V+Y+P
Sbjct: 1428 -VYEPAVFTINTKEAGAGGLALAV---EG-PSKTEIKCVDNQDGTCNVSYLP 1568

 Score =  200 bits (509), Expect = 6e-51,   Method: Compositional matrix adjust.
 Identities = 156/538 (28%), Positives = 243/538 (45%), Gaps = 20/538 (3%)
 Frame = +3

Query: 1565 RATVHDNKDGTYAVTYIPDKTGRYMIGVTYGGDNIPLSPYRIRATQTGDASKCLATGPGI 1624
            +    DN+DGT  V Y P K G+Y I V +G   I  SP+ ++     DASK    GPG+
Sbjct: 48   KMKCDDNRDGTCRVEYYPTKPGKYDISVLFGDKPIKDSPFSVKIQNPVDASKVKCYGPGL 227

Query: 1625 -APTVKTGEEVGFVVDAKTAGKGKVTCVILTP-DGTEAEADVIENEDGTYDIFYTAAKPG 1682
             A  V       F VDA+ AG+  +      P  G + EA+++  E+G Y   Y     G
Sbjct: 228  DASEVAANLPAVFTVDARDAGEAPLDVTFTDPLSGAQQEAEIVPVEEGLYQATYMPRAEG 407

Query: 1683 TYVIYVRFGGVDIPNSPFTVMVSRVPSPEPALTSRSTSTCWKLGEGRAQAVGSWVTEEAY 1742
               + V++GG  +PNSPF + V  +P  +P+    S       G G  ++V + +  +  
Sbjct: 408  KCKVDVKYGGKPVPNSPFHMQV--LPGVDPSKVKVS-------GPGVRRSVPASLPAQFT 560

Query: 1743 VPVSDMNGLGFKPFDLVIPFAVRKGEITGTVHMPSGKKATPEIVDNKDGTVTVRYAPTEV 1802
            V   D                    ++   V  P G    P   +N+DGT  V Y P ++
Sbjct: 561  VDTRDAG----------------VADLECMVQRPDGSFIKPYFQNNEDGTYDVIYTPEDL 692

Query: 1803 GLHEMHIKYRGSHIPGNPLQFYVNYPNSGSVSAYGPGLVYGV-ANKTATFTIVTEDAGEG 1861
            G++++ +KY G  +P +P           S      G    +   K    T+   DAG+G
Sbjct: 693  GVYDIIVKYDGQDVPRSPFNVEATPLGDASQCRITDGAERVIPIEKETVITVDAADAGKG 872

Query: 1862 GLDLAIEGPSKAEISC--IDNKDGTCTVTYLPTLPGDYSILVKYNDKHIPGSPFTAKITG 1919
             +   I  PS ++I    +D  DGT T++++P   G+Y I +K+    +P   +TA+   
Sbjct: 873  SVTCRIRSPSGSDIDIDIVDQGDGTFTISFIPQYAGEYIIEIKFGGNFVPDGQYTAEAVP 1052

Query: 1920 R------LCCFFSDDNRRCSQVKLGSAA---------DFLLDISETDLSTLTASIKAPSG 1964
                   L     DD     QV   +AA         DF   +     + ++AS+  PSG
Sbjct: 1053 EDEYEKYLQSRVVDDLIVADQVDQVNAAPGSGLYQPVDFQFPVGPI-FNFVSASVIMPSG 1229

Query: 1965 RDEPCLLKRLPNNHIGISFIPREVGEHLVSIKKNGNHVANSPVSIMVVQSEIGDARRAKV 2024
            +     ++   +  + + + P E G H + +K N   +  SP    V     G       
Sbjct: 1230 KTSYPKIEDNRDGTVTVRYQPTETGLHELHVKYNNECIQGSPFFFHVDSVNSG---YVTA 1400

Query: 2025 YGQGLSEGRTFEMSDFIVDTRDAGYGGISLAVEGPSKVDIQTEDLEDGTCKVSYFPTV 2082
            YG GLS G  +E + F ++T++AG GG++LAVEGPSK +I+  D +DGTC VSY P+V
Sbjct: 1401 YGPGLSHGVVYEPAVFTINTKEAGAGGLALAVEGPSKTEIKCVDNQDGTCNVSYLPSV 1574

 Score =  198 bits (504), Expect = 2e-50,   Method: Compositional matrix adjust.
 Identities = 154/511 (30%), Positives = 236/511 (46%), Gaps = 27/511 (5%)
 Frame = +3

Query: 1787 DNKDGTVTVRYAPTEVGLHEMHIKYRGSHIPGNPLQFYVNYP-NSGSVSAYGPGLVYG-- 1843
            DN+DGT  V Y PT+ G +++ + +    I  +P    +  P ++  V  YGPGL     
Sbjct: 63   DNRDGTCRVEYYPTKPGKYDISVLFGDKPIKDSPFSVKIQNPVDASKVKCYGPGLDASEV 242

Query: 1844 VANKTATFTIVTEDAGEGGLDLAIEGP---SKAEISCIDNKDGTCTVTYLPTLPGDYSIL 1900
             AN  A FT+   DAGE  LD+    P   ++ E   +  ++G    TY+P   G   + 
Sbjct: 243  AANLPAVFTVDARDAGEAPLDVTFTDPLSGAQQEAEIVPVEEGLYQATYMPRAEGKCKVD 422

Query: 1901 VKYNDKHIPGSPFTAKITGRL----CCFFSDDNRRCSQVKLGSAADFLLDISETDLSTLT 1956
            VKY  K +P SPF  ++   +            RR     L   A F +D  +  ++ L 
Sbjct: 423  VKYGGKPVPNSPFHMQVLPGVDPSKVKVSGPGVRRSVPASL--PAQFTVDTRDAGVADLE 596

Query: 1957 ASIKAPSGRDEPCLLKRLPNNHIGISFIPREVGEHLVSIKKNGNHVANSPVSIMVVQSEI 2016
              ++ P G       +   +    + + P ++G + + +K +G  V  SP ++    + +
Sbjct: 597  CMVQRPDGSFIKPYFQNNEDGTYDVIYTPEDLGVYDIIVKYDGQDVPRSPFNVEA--TPL 770

Query: 2017 GDARRAKVYGQGLSEGRTFEMSDFI-VDTRDAGYGGISLAVEGPS--KVDIQTEDLEDGT 2073
            GDA + ++   G       E    I VD  DAG G ++  +  PS   +DI   D  DGT
Sbjct: 771  GDASQCRI-TDGAERVIPIEKETVITVDAADAGKGSVTCRIRSPSGSDIDIDIVDQGDGT 947

Query: 2074 CKVSYFPTVPGVYIVSTKFADEHVPGSPFTVKISGEGR--------------VRESITRT 2119
              +S+ P   G YI+  KF    VP   +T +   E                V + + + 
Sbjct: 948  FTISFIPQYAGEYIIEIKFGGNFVPDGQYTAEAVPEDEYEKYLQSRVVDDLIVADQVDQV 1127

Query: 2120 SRAPAVATVGSICDLNLKIPEINSSDMSAHVTSPSGHVTEAEIVPMGKNSHCVRFVPQEM 2179
            + AP       + D    +  I +  +SA V  PSG  +  +I      +  VR+ P E 
Sbjct: 1128 NAAPGSGLYQPV-DFQFPVGPIFNF-VSASVIMPSGKTSYPKIEDNRDGTVTVRYQPTET 1301

Query: 2180 GVHTVSVKYRGQHVTGSPFQFTVGPLGEGGAHKVRAGGPGLERGEAGIPAEFSIWTREAG 2239
            G+H + VKY  + + GSPF F V  +  G    V A GPGL  G    PA F+I T+EAG
Sbjct: 1302 GLHELHVKYNNECIQGSPFFFHVDSVNSG---YVTAYGPGLSHGVVYEPAVFTINTKEAG 1472

Query: 2240 AGGLSIAVEGPSKAEITFDDHKNGSCGVSYI 2270
            AGGL++AVEGPSK EI   D+++G+C VSY+
Sbjct: 1473 AGGLALAVEGPSKTEIKCVDNQDGTCNVSYL 1565

 Score =  194 bits (494), Expect = 3e-49,   Method: Compositional matrix adjust.
 Identities = 160/550 (29%), Positives = 253/550 (46%), Gaps = 26/550 (4%)
 Frame = +3

Query: 773  GEGDVSVGIK--CDARVLSDDEEDVDFDIIHNANDTFTVKYVPPAPGRYTIKVLFASQEI 830
            G+G + +GI+   +A++  DD          N + T  V+Y P  PG+Y I VLF  + I
Sbjct: 3    GKGGLGLGIEGPVEAKMKCDD----------NRDGTCRVEYYPTKPGKYDISVLFGDKPI 152

Query: 831  PASPFRVKVDPSHDASKVKAEGPGLSKAGVENGKPTHFTVHTKGAGKAPLNVQFSSPLPG 890
              SPF VK+    DASKVK  GPGL  + V    P  FTV  + AG+APL+V F+ PL G
Sbjct: 153  KDSPFSVKIQNPVDASKVKCYGPGLDASEVAANLPAVFTVDARDAGEAPLDVTFTDPLSG 332

Query: 891  EAVKDLDIIDNYDYSHTVKYTPTQQGNMQVLVTYGGDPIPKSPFTVGVAAPLDLSKIKIN 950
             A ++ +I+   +  +   Y P  +G  +V V YGG P+P SPF + V   +D SK+K++
Sbjct: 333  -AQQEAEIVPVEEGLYQATYMPRAEGKCKVDVKYGGKPVPNSPFHMQVLPGVDPSKVKVS 509

Query: 951  --GLENRVEVGKDQEFAIDTNGAGGQGKLDVTILSPSRKVVPCLVAPVAGRECSTAKFI- 1007
              G+   V      +F +DT  A G   L+  +  P    +          E  T   I 
Sbjct: 510  GPGVRRSVPASLPAQFTVDTRDA-GVADLECMVQRPDGSFIKPY---FQNNEDGTYDVIY 677

Query: 1008 -PREEGLFAVDVTYDGHPVPGSPYTVEASLPPDPTKVKAHGPGLEGGLVGKPAEFTIDTK 1066
             P + G++ + V YDG  VP SP+ VEA+   D ++ +          + K    T+D  
Sbjct: 678  TPEDLGVYDIIVKYDGQDVPRSPFNVEATPLGDASQCRITDGAERVIPIEKETVITVDAA 857

Query: 1067 XXXXXXXXXXVEGP--CEAKIECSDNGDGTCSVSYLPTKPGEYFVNILFEEVHIPGSPFK 1124
                      +  P   +  I+  D GDGT ++S++P   GEY + I F    +P   + 
Sbjct: 858  DAGKGSVTCRIRSPSGSDIDIDIVDQGDGTFTISFIPQYAGEYIIEIKFGGNFVPDGQYT 1037

Query: 1125 ADIEMPFDPSKVVASGPGLEHGKVGEPGILCVDCSEAGPGT------------------L 1166
            A+  +P D  +       ++   V +     VD   A PG+                  +
Sbjct: 1038 AE-AVPEDEYEKYLQSRVVDDLIVADQ----VDQVNAAPGSGLYQPVDFQFPVGPIFNFV 1202

Query: 1167 GLEAVSDSGAKAEVSIQNNKDGTYAVTYVPLTAGMYTLTMKYGGELVPHFPAWVKVEPAI 1226
                +  SG  +   I++N+DGT  V Y P   G++ L +KY  E +   P +  V+ ++
Sbjct: 1203 SASVIMPSGKTSYPKIEDNRDGTVTVRYQPTETGLHELHVKYNNECIQGSPFFFHVD-SV 1379

Query: 1227 DTSGIKAFGPGIEGKDVFREATTDFTVDSRPLTQVGGDHIKAQITNPSGASTECFVKDNA 1286
            ++  + A+GPG+    V+  A   FT++++   + G   +   +  PS    +C   DN 
Sbjct: 1380 NSGYVTAYGPGLSHGVVYEPAV--FTINTK---EAGAGGLALAVEGPSKTEIKCV--DNQ 1538

Query: 1287 DGTYQVEYTP 1296
            DGT  V Y P
Sbjct: 1539 DGTCNVSYLP 1568

 Score =  170 bits (431), Expect = 6e-42,   Method: Compositional matrix adjust.
 Identities = 152/544 (27%), Positives = 241/544 (44%), Gaps = 37/544 (6%)
 Frame = +3

Query: 1955 LTASIKAPSGRDEPCLLKRLPNNHIGISFIPREVGEHLVSIKKNGNHVANSPVSIMVVQS 2014
            + A +K    RD  C           + + P + G++ +S+      + +SP S+ + Q+
Sbjct: 39   VEAKMKCDDNRDGTCR----------VEYYPTKPGKYDISVLFGDKPIKDSPFSVKI-QN 185

Query: 2015 EIGDARRAKVYGQGL--SEGRTFEMSDFIVDTRDAGYGGISLAVEGP---SKVDIQTEDL 2069
             + DA + K YG GL  SE      + F VD RDAG   + +    P   ++ + +   +
Sbjct: 186  PV-DASKVKCYGPGLDASEVAANLPAVFTVDARDAGEAPLDVTFTDPLSGAQQEAEIVPV 362

Query: 2070 EDGTCKVSYFPTVPGVYIVSTKFADEHVPGSPF-----------TVKISGEGRVRESITR 2118
            E+G  + +Y P   G   V  K+  + VP SPF            VK+SG G VR S+  
Sbjct: 363  EEGLYQATYMPRAEGKCKVDVKYGGKPVPNSPFHMQVLPGVDPSKVKVSGPG-VRRSVP- 536

Query: 2119 TSRAPAVATVGSICDLNLKIPEINSSDMSAHVTSPSGHVTEAEIVPMGKNSHCVRFVPQE 2178
             +  PA  TV +         +   +D+   V  P G   +         ++ V + P++
Sbjct: 537  -ASLPAQFTVDTR--------DAGVADLECMVQRPDGSFIKPYFQNNEDGTYDVIYTPED 689

Query: 2179 MGVHTVSVKYRGQHVTGSPFQFTVGPLGEGGAHKVRAGGPGLERGEAGIPAE----FSIW 2234
            +GV+ + VKY GQ V  SPF     PLG+    ++  G       E  IP E     ++ 
Sbjct: 690  LGVYDIIVKYDGQDVPRSPFNVEATPLGDASQCRITDGA------ERVIPIEKETVITVD 851

Query: 2235 TREAGAGGLSIAVEGPSKAEITFD--DHKNGSCGVSYIAQEPGNYEVSIKFNDEHIPDSP 2292
              +AG G ++  +  PS ++I  D  D  +G+  +S+I Q  G Y + IKF    +PD  
Sbjct: 852  AADAGKGSVTCRIRSPSGSDIDIDIVDQGDGTFTISFIPQYAGEYIIEIKFGGNFVPDGQ 1031

Query: 2293 YLVPVIAPSDD------ARCLTVLSLQESGLKVN--------QPASFAIRLNGAKGKIDA 2338
            Y    + P D+      +R +  L + +   +VN        QP  F   +      + A
Sbjct: 1032 YTAEAV-PEDEYEKYLQSRVVDDLIVADQVDQVNAAPGSGLYQPVDFQFPVGPIFNFVSA 1208

Query: 2339 KVHSPSGAVEECHVSELEPDKYAVRFIPHENGIHTIDVKFNGSHVVGSPFKVRVGEPGQA 2398
             V  PSG      + +       VR+ P E G+H + VK+N   + GSPF   V     +
Sbjct: 1209 SVIMPSGKTSYPKIEDNRDGTVTVRYQPTETGLHELHVKYNNECIQGSPFFFHV----DS 1376

Query: 2399 GNPALVSAYGAGLETGTTGIQSEFFINTTQAGPGTLSVTIEGPSKVKMDCQEIPEGY-KV 2457
             N   V+AYG GL  G     + F INT +AG G L++ +EGPSK ++ C +  +G   V
Sbjct: 1377 VNSGYVTAYGPGLSHGVVYEPAVFTINTKEAGAGGLALAVEGPSKTEIKCVDNQDGTCNV 1556

Query: 2458 MYTP 2461
             Y P
Sbjct: 1557 SYLP 1568

 Score =  151 bits (381), Expect = 3e-36,   Method: Compositional matrix adjust.
 Identities = 148/523 (28%), Positives = 228/523 (43%), Gaps = 31/523 (5%)
 Frame = +3

Query: 1859 GEGGLDLAIEGPSKAEISCIDNKDGTCTVTYLPTLPGDYSILVKYNDKHIPGSPFTAKI- 1917
            G+GGL L IEGP +A++ C DN+DGTC V Y PT PG Y I V + DK I  SPF+ KI 
Sbjct: 3    GKGGLGLGIEGPVEAKMKCDDNRDGTCRVEYYPTKPGKYDISVLFGDKPIKDSPFSVKIQ 182

Query: 1918 ----TGRLCCFFSDDNRRCSQVKLGSAADFLLDISETDLSTLTASIKAP-SGRDEPCLLK 1972
                  ++ C+        S+V     A F +D  +   + L  +   P SG  +   + 
Sbjct: 183  NPVDASKVKCYGP--GLDASEVAANLPAVFTVDARDAGEAPLDVTFTDPLSGAQQEAEIV 356

Query: 1973 RLPNNHIGISFIPREVGEHLVSIKKNGNHVANSPVSIMVVQSEIGDARRAKVYGQGLSEG 2032
             +       +++PR  G+  V +K  G  V NSP  + V+     D  + KV G G+   
Sbjct: 357  PVEEGLYQATYMPRAEGKCKVDVKYGGKPVPNSPFHMQVLPGV--DPSKVKVSGPGVRRS 530

Query: 2033 RTFEM-SDFIVDTRDAGYGGISLAVEGP--SKVDIQTEDLEDGTCKVSYFPTVPGVYIVS 2089
                + + F VDTRDAG   +   V+ P  S +    ++ EDGT  V Y P   GVY + 
Sbjct: 531  VPASLPAQFTVDTRDAGVADLECMVQRPDGSFIKPYFQNNEDGTYDVIYTPEDLGVYDII 710

Query: 2090 TKFADEHVPGSPFTVKISGEGRVRESITRTSRAPAVATVGSICDLNLKIPEINSSDMSAH 2149
             K+  + VP SPF V+ +  G   +    T  A  V  +     + +   +     ++  
Sbjct: 711  VKYDGQDVPRSPFNVEATPLGDASQCRI-TDGAERVIPIEKETVITVDAADAGKGSVTCR 887

Query: 2150 VTSPSGHVTEAEIVPMGKNSHCVRFVPQEMGVHTVSVKYRGQHVTGSPFQFTVGPLGEGG 2209
            + SPSG   + +IV  G  +  + F+PQ  G + + +K+ G  V     Q+T   + E  
Sbjct: 888  IRSPSGSDIDIDIVDQGDGTFTISFIPQYAGEYIIEIKFGGNFVPDG--QYTAEAVPEDE 1061

Query: 2210 AHKV-------------------RAGGPGLERGEAGIPAEFSIWTREAGAGGLSIAVEGP 2250
              K                     A G GL +     P +F           +S +V  P
Sbjct: 1062 YEKYLQSRVVDDLIVADQVDQVNAAPGSGLYQ-----PVDFQFPVGPI-FNFVSASVIMP 1223

Query: 2251 S--KAEITFDDHKNGSCGVSYIAQEPGNYEVSIKFNDEHIPDSPYLVPVIAPSDDARCLT 2308
            S   +    +D+++G+  V Y   E G +E+ +K+N+E I  SP+   V   S ++  +T
Sbjct: 1224 SGKTSYPKIEDNRDGTVTVRYQPTETGLHELHVKYNNECIQGSPFFFHV--DSVNSGYVT 1397

Query: 2309 VLSLQESGLKVNQPASFAIRLNGA-KGKIDAKVHSPSGAVEEC 2350
                  S   V +PA F I    A  G +   V  PS    +C
Sbjct: 1398 AYGPGLSHGVVYEPAVFTINTKEAGAGGLALAVEGPSKTEIKC 1526

 Score =  150 bits (378), Expect = 9e-36,   Method: Compositional matrix adjust.
 Identities = 138/541 (25%), Positives = 221/541 (40%), Gaps = 29/541 (5%)
 Frame = +3

Query: 302 EARVTPDSDKNKTYSVEYLPKVTGLHKVIVLFAGQHISKSPFEVNVDKAQGDASKVTAKG 361
           EA++  D +++ T  VEY P   G + + VLF  + I  SPF V +     DASKV   G
Sbjct: 42  EAKMKCDDNRDGTCRVEYYPTKPGKYDISVLFGDKPIKDSPFSVKIQNPV-DASKVKCYG 218

Query: 362 PGLETTGNIANKPTYFDIYTAGAGVGDIGIEVEDPQGKNSVELLVEDRGNQVYRCVYKPV 421
           PGL+ +   AN P  F +    AG   + +   DP      E  +      +Y+  Y P 
Sbjct: 219 PGLDASEVAANLPAVFTVDARDAGEAPLDVTFTDPLSGAQQEAEIVPVEEGLYQATYMPR 398

Query: 422 QPGPHVVKVSFAGDAIPKSPFGVQIGEACNPNACRASGRGLQPKGVRIRETADFKVDTKA 481
             G   V V + G  +P SPF +Q+    +P+  + SG G++ + V     A F VDT+ 
Sbjct: 399 AEGKCKVDVKYGGKPVPNSPFHMQVLPGVDPSKVKVSGPGVR-RSVPASLPAQFTVDTRD 575

Query: 482 AGSGELGVTVKGPKGLEELVKQKGFLDGVYSFEYYPSTPGKYSVAVTWGGHHIPKSPFEV 541
           AG  +L   V+ P G       +   DG Y   Y P   G Y + V + G  +P+SPF V
Sbjct: 576 AGVADLECMVQRPDGSFIKPYFQNNEDGTYDVIYTPEDLGVYDIIVKYDGQDVPRSPFNV 755

Query: 542 QVGPEAGMQKVRAWGPGLHGGIVGRSADFVVESIGSEVGTLGFAIEGPSQAKIEYD--DQ 599
           +  P     + R          + +     V++  +  G++   I  PS + I+ D  DQ
Sbjct: 756 EATPLGDASQCRITDGAERVIPIEKETVITVDAADAGKGSVTCRIRSPSGSDIDIDIVDQ 935

Query: 600 NDGSCDVKYWPKEPGEYAVHIMCDDEDIKDSPYMAFIHPATGDYNPDLVQAYGPGLEKSG 659
            DG+  + + P+  GEY + I      + D  Y A   P       D  + Y   L+   
Sbjct: 936 GDGTFTISFIPQYAGEYIIEIKFGGNFVPDGQYTAEAVPE------DEYEKY---LQSR- 1085

Query: 660 CTINNPAEFIVDPKDAGSAPLKILAQDGEG--QPIDIQ---------------------- 695
                    +VD         ++ A  G G  QP+D Q                      
Sbjct: 1086---------VVDDLIVADQVDQVNAAPGSGLYQPVDFQFPVGPIFNFVSASVIMPSGKTS 1238

Query: 696 ---MKSRMDGTYACSYTPLKAIKHTIAVVWGGVNIPHSPYRVNIGQGSHPQKVKVFGPGV 752
              ++   DGT    Y P +   H + V +    I  SP+  ++    +   V  +GPG+
Sbjct: 1239YPKIEDNRDGTVTVRYQPTETGLHELHVKYNNECIQGSPFFFHV-DSVNSGYVTAYGPGL 1415

Query: 753 ERSGLKANEPTHFTVDCTEAGEGDVSVGIKCDARVLSDDEEDVDFDIIHNANDTFTVKYV 812
               +   EP  FT++  EAG G +++ ++  ++         +   + N + T  V Y+
Sbjct: 1416SHGVVY--EPAVFTINTKEAGAGGLALAVEGPSK--------TEIKCVDNQDGTCNVSYL 1565

Query: 813 P 813
           P
Sbjct: 1566P 1568

 Score =  148 bits (374), Expect = 2e-35,   Method: Compositional matrix adjust.
 Identities = 134/478 (28%), Positives = 215/478 (44%), Gaps = 25/478 (5%)
 Frame = +3

Query: 258 RAYGRGIEPTGNMVKQPAKFTVDTISAGQGDVMVFVEDP-EGNKEEARVTPDSDKNKTYS 316
           + YG G++ +      PA FTVD   AG+  + V   DP  G ++EA + P  +    Y 
Sbjct: 207 KCYGPGLDASEVAANLPAVFTVDARDAGEAPLDVTFTDPLSGAQQEAEIVPVEE--GLYQ 380

Query: 317 VEYLPKVTGLHKVIVLFAGQHISKSPFEVNVDKAQGDASKVTAKGPGLETTGNIANKPTY 376
             Y+P+  G  KV V + G+ +  SPF + V     D SKV   GPG+  +   A+ P  
Sbjct: 381 ATYMPRAEGKCKVDVKYGGKPVPNSPFHMQVLPGV-DPSKVKVSGPGVRRSVP-ASLPAQ 554

Query: 377 FDIYTAGAGVGDIGIEVEDPQGKNSVELLVEDRGNQVYRCVYKPVQPGPHVVKVSFAGDA 436
           F + T  AGV D+   V+ P G + ++   ++  +  Y  +Y P   G + + V + G  
Sbjct: 555 FTVDTRDAGVADLECMVQRPDG-SFIKPYFQNNEDGTYDVIYTPEDLGVYDIIVKYDGQD 731

Query: 437 IPKSPFGVQIGEACNPNACRASGRGLQPKGVRIRETADFKVDTKAAGSGELGVTVKGPKG 496
           +P+SPF V+     + + CR +      + + I +     VD   AG G +   ++ P G
Sbjct: 732 VPRSPFNVEATPLGDASQCRITDGA--ERVIPIEKETVITVDAADAGKGSVTCRIRSPSG 905

Query: 497 LEELVKQKGFLDGVYSFEYYPSTPGKYSVAVTWGGHHIPKSPFEVQVGPEAGMQKV---- 552
            +  +      DG ++  + P   G+Y + + +GG+ +P   +  +  PE   +K     
Sbjct: 906 SDIDIDIVDQGDGTFTISFIPQYAGEYIIEIKFGGNFVPDGQYTAEAVPEDEYEKYLQSR 1085

Query: 553 ---------------RAWGPGLHGGI-----VGRSADFVVESIGSEVGTLGFAIEGPSQA 592
                           A G GL+  +     VG   +FV  S+    G   +        
Sbjct: 1086VVDDLIVADQVDQVNAAPGSGLYQPVDFQFPVGPIFNFVSASVIMPSGKTSY-------P 1244

Query: 593 KIEYDDQNDGSCDVKYWPKEPGEYAVHIMCDDEDIKDSPYMAFIHPATGDYNPDLVQAYG 652
           KIE  D  DG+  V+Y P E G + +H+  ++E I+ SP+  F H      N   V AYG
Sbjct: 1245KIE--DNRDGTVTVRYQPTETGLHELHVKYNNECIQGSPF--FFH--VDSVNSGYVTAYG 1406

Query: 653 PGLEKSGCTINNPAEFIVDPKDAGSAPLKILAQDGEGQPIDIQMKSRMDGTYACSYTP 710
           PGL  S   +  PA F ++ K+AG+  L  LA +G  +  +I+     DGT   SY P
Sbjct: 1407PGL--SHGVVYEPAVFTINTKEAGAGGLA-LAVEGPSK-TEIKCVDNQDGTCNVSYLP 1568

 Score =  125 bits (314), Expect = 2e-28,   Method: Compositional matrix adjust.
 Identities = 101/380 (26%), Positives = 173/380 (45%), Gaps = 8/380 (2%)
 Frame = +3

Query: 2239 GAGGLSIAVEGPSKAEITFDDHKNGSCGVSYIAQEPGNYEVSIKFNDEHIPDSPYLVPVI 2298
            G GGL + +EGP +A++  DD+++G+C V Y   +PG Y++S+ F D+ I DSP+ V + 
Sbjct: 3    GKGGLGLGIEGPVEAKMKCDDNRDGTCRVEYYPTKPGKYDISVLFGDKPIKDSPFSVKIQ 182

Query: 2299 APSDDARCLTV-LSLQESGLKVNQPASFAIRLNGA-KGKIDAKVHSP-SGAVEECHVSEL 2355
             P D ++       L  S +  N PA F +    A +  +D     P SGA +E  +  +
Sbjct: 183  NPVDASKVKCYGPGLDASEVAANLPAVFTVDARDAGEAPLDVTFTDPLSGAQQEAEIVPV 362

Query: 2356 EPDKYAVRFIPHENGIHTIDVKFNGSHVVGSPFKVRVGEPGQAGNPALVSAYGAGLETGT 2415
            E   Y   ++P   G   +DVK+ G  V  SPF ++V  PG   +P+ V   G G+    
Sbjct: 363  EEGLYQATYMPRAEGKCKVDVKYGGKPVPNSPFHMQV-LPGV--DPSKVKVSGPGVRRSV 533

Query: 2416 -TGIQSEFFINTTQAGPGTLSVTIEGP--SKVKMDCQEIPEG-YKVMYTPMAPGNYLIGV 2471
               + ++F ++T  AG   L   ++ P  S +K   Q   +G Y V+YTP   G Y I V
Sbjct: 534  PASLPAQFTVDTRDAGVADLECMVQRPDGSFIKPYFQNNEDGTYDVIYTPEDLGVYDIIV 713

Query: 2472 KYGGPNHISRSPFKAKVTGQRLVSPGSANETSSILVESVTRSSTETCYSAIPKSSSDASK 2531
            KY G   + RSPF  + T                                 P   +   +
Sbjct: 714  KYDG-QDVPRSPFNVEAT---------------------------------PLGDASQCR 791

Query: 2532 VTSKGAGLSKAFVGQKSSFL-VDCSKAGSNMLLIGVHGPTTPCEEVSMKHVGKQQYNVTY 2590
            +T    G  +    +K + + VD + AG   +   +  P+    ++ +   G   + +++
Sbjct: 792  ITD---GAERVIPIEKETVITVDAADAGKGSVTCRIRSPSGSDIDIDIVDQGDGTFTISF 962

Query: 2591 VVKERGDYVLAVKWGEEHIP 2610
            + +  G+Y++ +K+G   +P
Sbjct: 963  IPQYAGEYIIEIKFGGNFVP 1022

 Score = 62.4 bits (150), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 56/193 (29%), Positives = 79/193 (40%), Gaps = 4/193 (2%)
 Frame = +3

Query: 2430 GPGTLSVTIEGPSKVKMDCQEIPEGY-KVMYTPMAPGNYLIGVKYGGPNHISRSPFKAKV 2488
            G G L + IEGP + KM C +  +G  +V Y P  PG Y I V +G    I  SPF  K+
Sbjct: 3    GKGGLGLGIEGPVEAKMKCDDNRDGTCRVEYYPTKPGKYDISVLFGD-KPIKDSPFSVKI 179

Query: 2489 TGQRLVSPGSANETSSILVESVTRSSTETCYSAIPKSSSDASKVTSKGAGLSKAFVGQK- 2547
                                               ++  DASKV   G GL  + V    
Sbjct: 180  -----------------------------------QNPVDASKVKCYGPGLDASEVAANL 254

Query: 2548 -SSFLVDCSKAGSNMLLIGVHGPTTPCE-EVSMKHVGKQQYNVTYVVKERGDYVLAVKWG 2605
             + F VD   AG   L +    P +  + E  +  V +  Y  TY+ +  G   + VK+G
Sbjct: 255  PAVFTVDARDAGEAPLDVTFTDPLSGAQQEAEIVPVEEGLYQATYMPRAEGKCKVDVKYG 434

Query: 2606 EEHIPGSPFHVTV 2618
             + +P SPFH+ V
Sbjct: 435  GKPVPNSPFHMQV 473

 Score = 31.2 bits (69), Expect = 6.0,   Method: Compositional matrix adjust.
 Identities = 21/68 (30%), Positives = 36/68 (52%), Gaps = 2/68 (2%)
 Frame = +3

Query: 2526 SSDASKVTSKGAGLSKAFVGQKSSFLVDCSKAGSNMLLIGVHGPTTPCEEVSMKHVGKQQ 2585
            S ++  VT+ G GLS   V + + F ++  +AG+  L + V GP+    +  +K V  Q 
Sbjct: 1374 SVNSGYVTAYGPGLSHGVVYEPAVFTINTKEAGAGGLALAVEGPS----KTEIKCVDNQD 1541

Query: 2586 --YNVTYV 2591
               NV+Y+
Sbjct: 1542 GTCNVSYL 1565
>16231
          Length = 1393

 Score =  245 bits (625), Expect(2) = 6e-74,   Method: Compositional matrix adjust.
 Identities = 135/288 (46%), Positives = 186/288 (64%), Gaps = 5/288 (1%)
 Frame = +3

Query: 286 QGDVMVFVEDPEGNKEEARVTPDSDKNKTYSVEYLPKVTGLHKVIVLFAGQHISKSPFEV 345
           +GDV V + +P+G +E   V  ++D+N TYS  Y+P + G +KV +LFA + I+KSPF V
Sbjct: 177 KGDVEVSILNPKGVEETCEVEFNNDRNLTYSCAYVPTMEGHYKVNILFANKVIAKSPFTV 356

Query: 346 NVDKAQGDASKVTAKGPGLETTGNIANKPTYFDIYTAGAGVGDIGIEVEDPQG-KNSVEL 404
            V+ A GDASKVTA GPGLE TG +A K T+F+++  GAG G + + + DP G K++V  
Sbjct: 357 TVEGAAGDASKVTASGPGLEKTGVVATKKTFFEVFVKGAGNGKVDVVILDPHGRKDNVRP 536

Query: 405 LVEDRGNQ--VYRCVYKPVQPGPHVVKVSFAGDAIPKSPFGVQIGEACNPNACRASGRGL 462
            V+   ++   Y   Y  +  G H V V FAG  IP SPFGVQ+  A N  AC A+GRG+
Sbjct: 537 KVQSAPDKDATYLVEYVTIDQGLHSVNVFFAGSQIPNSPFGVQVAPASNAKACYATGRGV 716

Query: 463 QPKGVRIRETADFKVDTKAAGSGELGVTVKGPKGLEELVKQKGFLDG--VYSFEYYPSTP 520
           QP+GVR+++ ADF V TK AG GE+ V + GP G+EE  + K   D   V+   Y PS P
Sbjct: 717 QPRGVRVKDRADFYVHTKGAGDGEVAVQIIGPGGVEEKCQLKKVPDQPEVWECVYNPSKP 896

Query: 521 GKYSVAVTWGGHHIPKSPFEVQVGPEAGMQKVRAWGPGLHGGIVGRSA 568
           G Y + +T+G  HI KSPF+++VGP     K+RA+GPGL GG+V + A
Sbjct: 897 GNYIINITFGDQHISKSPFKIEVGPYK-ESKIRAYGPGLEGGVVQQKA 1037

 Score = 53.9 bits (128), Expect(2) = 6e-74,   Method: Composition-based stats.
 Identities = 28/59 (47%), Positives = 33/59 (55%)
 Frame = +1

Query: 229 SVMTYLSQFXXXXXXXXXXXXXXXXXXXXRAYGRGIEPTGNMVKQPAKFTVDTISAGQG 287
           S+MTYLSQF                    RAYG G+EP GN V  PA+FTV+T SAG+G
Sbjct: 7   SMMTYLSQFPNAKLKAGAPLRPRLNPARVRAYGPGLEPKGNQVGAPARFTVETFSAGRG 183

 Score =  108 bits (271), Expect(2) = 1e-38,   Method: Compositional matrix adjust.
 Identities = 86/272 (31%), Positives = 123/272 (45%), Gaps = 14/272 (5%)
 Frame = +3

Query: 1178 AEVSIQNNKDGTYAVTYVPLTAGMYTLTMKYGGELVPHFPAWVKVEPAI-DTSGIKAFGP 1236
             EV   N+++ TY+  YVP   G Y + + +  +++   P  V VE A  D S + A GP
Sbjct: 228  CEVEFNNDRNLTYSCAYVPTMEGHYKVNILFANKVIAKSPFTVTVEGAAGDASKVTASGP 407

Query: 1237 GIEGKDVFREATTDFTVDSRPLTQVGGDHIKAQITNPSGASTECFVK----DNADGTYQV 1292
            G+E   V     T F V  +     G   +   I +P G       K     + D TY V
Sbjct: 408  GLEKTGVVATKKTFFEVFVK---GAGNGKVDVVILDPHGRKDNVRPKVQSAPDKDATYLV 578

Query: 1293 EYTPFEKGFHVVEVTYDDVPIPNSPFKVAVTEGCQPSRVHAQGPGLKEAFTNKSNV--FT 1350
            EY   ++G H V V +    IPNSPF V V         +A G G++       +   F 
Sbjct: 579  EYVTIDQGLHSVNVFFAGSQIPNSPFGVQVAPASNAKACYATGRGVQPRGVRVKDRADFY 758

Query: 1351 VVTRGAGIGGLGITVEGPSESKINCRDNK----DGSCSAEYIPFAPGDYDVNITYGGVHI 1406
            V T+GAG G + + + GP   +  C+  K           Y P  PG+Y +NIT+G  HI
Sbjct: 759  VHTKGAGDGEVAVQIIGPGGVEEKCQLKKVPDQPEVWECVYNPSKPGNYIINITFGDQHI 938

Query: 1407 PGSPFRV---PSKDVVDPSKVKIAGPGLSSCV 1435
              SPF++   P K+    SK++  GPGL   V
Sbjct: 939  SKSPFKIEVGPYKE----SKIRAYGPGLEGGV 1022

 Score = 72.0 bits (175), Expect(2) = 1e-38,   Method: Compositional matrix adjust.
 Identities = 37/94 (39%), Positives = 53/94 (56%), Gaps = 2/94 (2%)
 Frame = +2

Query: 1469 VNVVDNGDGTHTVTYTPSQEGPYIVSVKYADEEIPRSPFKVKVLPT--YDASKVTASGPG 1526
            +  +DNGDG+  V Y P+  G Y V +  +DE+IP+SPF   + P   +DA KV A GPG
Sbjct: 1109 IECLDNGDGSADVWYLPTMPGEYAVHILCSDEDIPKSPFMADIKPAADFDAEKVIAKGPG 1288

Query: 1527 LSAYGVPASLPVEFAIDARDAGEGLLAVQITDQE 1560
            L   GV  +   EF +D + AG+  L +   D +
Sbjct: 1289 LEKSGVAPNKWAEFTVDTKAAGKAPLVITGMDTD 1390

 Score =  115 bits (287), Expect(3) = 9e-38,   Method: Compositional matrix adjust.
 Identities = 87/283 (30%), Positives = 129/283 (45%), Gaps = 7/283 (2%)
 Frame = +3

Query: 676 GSAPLKILAQDGEGQPIDIQMKSRMDGTYACSYTPLKAIKHTIAVVWGGVNIPHSPYRVN 735
           G   + IL   G  +  +++  +  + TY+C+Y P     + + +++    I  SP+ V 
Sbjct: 180 GDVEVSILNPKGVEETCEVEFNNDRNLTYSCAYVPTMEGHYKVNILFANKVIAKSPFTVT 359

Query: 736 I-GQGSHPQKVKVFGPGVERSGLKANEPTHFTVDCTEAGEGDVSV------GIKCDARVL 788
           + G      KV   GPG+E++G+ A + T F V    AG G V V      G K + R  
Sbjct: 360 VEGAAGDASKVTASGPGLEKTGVVATKKTFFEVFVKGAGNGKVDVVILDPHGRKDNVRPK 539

Query: 789 SDDEEDVDFDIIHNANDTFTVKYVPPAPGRYTIKVLFASQEIPASPFRVKVDPSHDASKV 848
                D D         T+ V+YV    G +++ V FA  +IP SPF V+V P+ +A   
Sbjct: 540 VQSAPDKD--------ATYLVEYVTIDQGLHSVNVFFAGSQIPNSPFGVQVAPASNAKAC 695

Query: 849 KAEGPGLSKAGVENGKPTHFTVHTKGAGKAPLNVQFSSPLPGEAVKDLDIIDNYDYSHTV 908
            A G G+   GV       F VHTKGAG   + VQ   P   E    L  + +       
Sbjct: 696 YATGRGVQPRGVRVKDRADFYVHTKGAGDGEVAVQIIGPGGVEEKCQLKKVPDQPEVWEC 875

Query: 909 KYTPTQQGNMQVLVTYGGDPIPKSPFTVGVAAPLDLSKIKING 951
            Y P++ GN  + +T+G   I KSPF + V  P   SKI+  G
Sbjct: 876 VYNPSKPGNYIINITFGDQHISKSPFKIEV-GPYKESKIRAYG 1001

 Score = 47.0 bits (110), Expect(3) = 9e-38,   Method: Compositional matrix adjust.
 Identities = 37/107 (34%), Positives = 53/107 (49%), Gaps = 4/107 (3%)
 Frame = +2

Query: 964  FAIDTNGAGGQGKLDVTILSPSRKVVPCLVAPVAGRECSTAKFIPREEGLFAVDVTYDGH 1023
            F ++TNG    G L  +I  PS+  + CL     G   +   ++P   G +AV +     
Sbjct: 1040 FTVETNGE--TGALGFSIEGPSQAQIECLDN---GDGSADVWYLPTMPGEYAVHILCSDE 1204

Query: 1024 PVPGSPYT--VEASLPPDPTKVKAHGPGLEGGLVG--KPAEFTIDTK 1066
             +P SP+   ++ +   D  KV A GPGLE   V   K AEFT+DTK
Sbjct: 1205 DIPKSPFMADIKPAADFDAEKVIAKGPGLEKSGVAPNKWAEFTVDTK 1345

 Score = 36.2 bits (82), Expect(3) = 9e-38,   Method: Composition-based stats.
 Identities = 18/40 (45%), Positives = 22/40 (55%)
 Frame = +1

Query: 644 NPDLVQAYGPGLEKSGCTINNPAEFIVDPKDAGSAPLKIL 683
           NP  V+AYGPGLE  G  +  PA F V+   AG    + L
Sbjct: 79  NPARVRAYGPGLEPKGNQVGAPARFTVETFSAGRGMWRCL 198

 Score =  118 bits (296), Expect(3) = 2e-36,   Method: Compositional matrix adjust.
 Identities = 80/275 (29%), Positives = 132/275 (48%), Gaps = 4/275 (1%)
 Frame = +3

Query: 592 AKIEYDDQNDGSCDVKYWPKEPGEYAVHIMCDDEDIKDSPYMAFIHPATGDYNPDLVQAY 651
            ++E+++  + +    Y P   G Y V+I+  ++ I  SP+   +  A GD +   V A 
Sbjct: 228 CEVEFNNDRNLTYSCAYVPTMEGHYKVNILFANKVIAKSPFTVTVEGAAGDASK--VTAS 401

Query: 652 GPGLEKSGCTINNPAEFIVDPKDAGSAPLKILAQDGEGQPIDIQMKSR----MDGTYACS 707
           GPGLEK+G        F V  K AG+  + ++  D  G+  +++ K +     D TY   
Sbjct: 402 GPGLEKTGVVATKKTFFEVFVKGAGNGKVDVVILDPHGRKDNVRPKVQSAPDKDATYLVE 581

Query: 708 YTPLKAIKHTIAVVWGGVNIPHSPYRVNIGQGSHPQKVKVFGPGVERSGLKANEPTHFTV 767
           Y  +    H++ V + G  IP+SP+ V +   S+ +     G GV+  G++  +   F V
Sbjct: 582 YVTIDQGLHSVNVFFAGSQIPNSPFGVQVAPASNAKACYATGRGVQPRGVRVKDRADFYV 761

Query: 768 DCTEAGEGDVSVGIKCDARVLSDDEEDVDFDIIHNANDTFTVKYVPPAPGRYTIKVLFAS 827
               AG+G+V+V I     V    EE      + +  + +   Y P  PG Y I + F  
Sbjct: 762 HTKGAGDGEVAVQIIGPGGV----EEKCQLKKVPDQPEVWECVYNPSKPGNYIINITFGD 929

Query: 828 QEIPASPFRVKVDPSHDASKVKAEGPGLSKAGVEN 862
           Q I  SPF+++V P +  SK++A GPGL    V+ 
Sbjct: 930 QHISKSPFKIEVGP-YKESKIRAYGPGLEGGVVQQ 1031

 Score = 47.4 bits (111), Expect(3) = 2e-36,   Method: Compositional matrix adjust.
 Identities = 42/111 (37%), Positives = 52/111 (46%), Gaps = 5/111 (4%)
 Frame = +2

Query: 867  HFTVHTKGAGKAPLNVQFSSPLPGEAVKDLDIIDNYDYSHTVKYTPTQQGNMQVLVTYGG 926
             FTV T G   A   + FS   P +A   ++ +DN D S  V Y PT  G   V +    
Sbjct: 1037 RFTVETNGETGA---LGFSIEGPSQA--QIECLDNGDGSADVWYLPTMPGEYAVHILCSD 1201

Query: 927  DPIPKSPFTVGV--AAPLDLSKI--KINGLENR-VEVGKDQEFAIDTNGAG 972
            + IPKSPF   +  AA  D  K+  K  GLE   V   K  EF +DT  AG
Sbjct: 1202 EDIPKSPFMADIKPAADFDAEKVIAKGPGLEKSGVAPNKWAEFTVDTKAAG 1354

 Score = 27.7 bits (60), Expect(3) = 2e-36,   Method: Composition-based stats.
 Identities = 16/38 (42%), Positives = 20/38 (52%), Gaps = 2/38 (5%)
 Frame = +1

Query: 545 PEAGMQKVRAWGPGLH--GGIVGRSADFVVESIGSEVG 580
           P     +VRA+GPGL   G  VG  A F VE+  +  G
Sbjct: 70  PRLNPARVRAYGPGLEPKGNQVGAPARFTVETFSAGRG 183

 Score =  142 bits (359), Expect = 1e-33,   Method: Compositional matrix adjust.
 Identities = 93/260 (35%), Positives = 136/260 (52%), Gaps = 10/260 (3%)
 Frame = +3

Query: 1455 LEVRVLGPRGLVEPVNVVDNGDG--THTVTYTPSQEGPYIVSVKYADEEIPRSPFKVKVL 1512
            +EV +L P+G+ E   V  N D   T++  Y P+ EG Y V++ +A++ I +SPF V V 
Sbjct: 186  VEVSILNPKGVEETCEVEFNNDRNLTYSCAYVPTMEGHYKVNILFANKVIAKSPFTVTVE 365

Query: 1513 -PTYDASKVTASGPGLSAYGVPASLPVEFAIDARDAGEGLLAVQITDQEGKPQ--RATVH 1569
                DASKVTASGPGL   GV A+    F +  + AG G + V I D  G+    R  V 
Sbjct: 366  GAAGDASKVTASGPGLEKTGVVATKKTFFEVFVKGAGNGKVDVVILDPHGRKDNVRPKVQ 545

Query: 1570 D--NKDGTYAVTYIPDKTGRYMIGVTYGGDNIPLSPYRIRATQTGDASKCLATGPGIAPT 1627
               +KD TY V Y+    G + + V + G  IP SP+ ++     +A  C ATG G+ P 
Sbjct: 546  SAPDKDATYLVEYVTIDQGLHSVNVFFAGSQIPNSPFGVQVAPASNAKACYATGRGVQPR 725

Query: 1628 -VKTGEEVGFVVDAKTAGKGKVTCVILTPDGTEAEADV--IENEDGTYDIFYTAAKPGTY 1684
             V+  +   F V  K AG G+V   I+ P G E +  +  + ++   ++  Y  +KPG Y
Sbjct: 726  GVRVKDRADFYVHTKGAGDGEVAVQIIGPGGVEEKCQLKKVPDQPEVWECVYNPSKPGNY 905

Query: 1685 VIYVRFGGVDIPNSPFTVMV 1704
            +I + FG   I  SPF + V
Sbjct: 906  IINITFGDQHISKSPFKIEV 965

 Score =  108 bits (271), Expect(2) = 1e-31,   Method: Compositional matrix adjust.
 Identities = 74/208 (35%), Positives = 106/208 (50%), Gaps = 3/208 (1%)
 Frame = +3

Query: 259 AYGRGIEPTGNMVKQPAKFTVDTISAGQGDVMVFVEDPEGNKEEAR--VTPDSDKNKTYS 316
           A G G+E TG +  +   F V    AG G V V + DP G K+  R  V    DK+ TY 
Sbjct: 396 ASGPGLEKTGVVATKKTFFEVFVKGAGNGKVDVVILDPHGRKDNVRPKVQSAPDKDATYL 575

Query: 317 VEYLPKVTGLHKVIVLFAGQHISKSPFEVNVDKAQGDASKVTAKGPGLETTGNIANKPTY 376
           VEY+    GLH V V FAG  I  SPF V V  A  +A    A G G++  G        
Sbjct: 576 VEYVTIDQGLHSVNVFFAGSQIPNSPFGVQVAPAS-NAKACYATGRGVQPRGVRVKDRAD 752

Query: 377 FDIYTAGAGVGDIGIEVEDPQG-KNSVELLVEDRGNQVYRCVYKPVQPGPHVVKVSFAGD 435
           F ++T GAG G++ +++  P G +   +L       +V+ CVY P +PG +++ ++F   
Sbjct: 753 FYVHTKGAGDGEVAVQIIGPGGVEEKCQLKKVPDQPEVWECVYNPSKPGNYIINITFGDQ 932

Query: 436 AIPKSPFGVQIGEACNPNACRASGRGLQ 463
            I KSPF +++G     +  RA G GL+
Sbjct: 933 HISKSPFKIEVGPY-KESKIRAYGPGLE 1013

 Score = 48.5 bits (114), Expect(2) = 1e-31,   Method: Compositional matrix adjust.
 Identities = 36/104 (34%), Positives = 52/104 (50%), Gaps = 4/104 (3%)
 Frame = +2

Query: 475  FKVDTKAAGSGELGVTVKGPKGLEELVKQKGFLDGVYSFEYYPSTPGKYSVAVTWGGHHI 534
            F V+T    +G LG +++GP   +      G  DG     Y P+ PG+Y+V +      I
Sbjct: 1040 FTVETNGE-TGALGFSIEGPSQAQIECLDNG--DGSADVWYLPTMPGEYAVHILCSDEDI 1210

Query: 535  PKSPFEVQVGPEAGM--QKVRAWGPGLHGGIVG--RSADFVVES 574
            PKSPF   + P A    +KV A GPGL    V   + A+F V++
Sbjct: 1211 PKSPFMADIKPAADFDAEKVIAKGPGLEKSGVAPNKWAEFTVDT 1342

 Score =  111 bits (278), Expect(3) = 8e-31,   Method: Compositional matrix adjust.
 Identities = 90/268 (33%), Positives = 127/268 (47%), Gaps = 8/268 (2%)
 Frame = +3

Query: 1365 VEGPSESKINCRDNKDGSCSAEYIPFAPGDYDVNITYGGVHIPGSPFRVPSKDVV-DPSK 1423
            VE   E + N   N   SC+  Y+P   G Y VNI +    I  SPF V  +    D SK
Sbjct: 216  VEETCEVEFNNDRNLTYSCA--YVPTMEGHYKVNILFANKVIAKSPFTVTVEGAAGDASK 389

Query: 1424 VKIAGPGLSSC-VRACIPQSFTVDSSKAGLAPLEVRVLGPRGL---VEP-VNVVDNGDGT 1478
            V  +GPGL    V A     F V    AG   ++V +L P G    V P V    + D T
Sbjct: 390  VTASGPGLEKTGVVATKKTFFEVFVKGAGNGKVDVVILDPHGRKDNVRPKVQSAPDKDAT 569

Query: 1479 HTVTYTPSQEGPYIVSVKYADEEIPRSPFKVKVLPTYDASKVTASGPGLSAYGVPASLPV 1538
            + V Y    +G + V+V +A  +IP SPF V+V P  +A    A+G G+   GV      
Sbjct: 570  YLVEYVTIDQGLHSVNVFFAGSQIPNSPFGVQVAPASNAKACYATGRGVQPRGVRVKDRA 749

Query: 1539 EFAIDARDAGEGLLAVQITDQEGKPQRATVHDNKDG--TYAVTYIPDKTGRYMIGVTYGG 1596
            +F +  + AG+G +AVQI    G  ++  +    D    +   Y P K G Y+I +T+G 
Sbjct: 750  DFYVHTKGAGDGEVAVQIIGPGGVEEKCQLKKVPDQPEVWECVYNPSKPGNYIINITFGD 929

Query: 1597 DNIPLSPYRIRATQTGDASKCLATGPGI 1624
             +I  SP++I      + SK  A GPG+
Sbjct: 930  QHISKSPFKIEVGPYKE-SKIRAYGPGL 1010

 Score = 40.0 bits (92), Expect(3) = 8e-31,   Method: Compositional matrix adjust.
 Identities = 15/43 (34%), Positives = 27/43 (62%)
 Frame = +2

Query: 1658 TEAEADVIENEDGTYDIFYTAAKPGTYVIYVRFGGVDIPNSPF 1700
            ++A+ + ++N DG+ D++Y    PG Y +++     DIP SPF
Sbjct: 1097 SQAQIECLDNGDGSADVWYLPTMPGEYAVHILCSDEDIPKSPF 1225

 Score = 23.1 bits (48), Expect(3) = 8e-31,   Method: Composition-based stats.
 Identities = 19/50 (38%), Positives = 22/50 (44%), Gaps = 4/50 (8%)
 Frame = +1

Query: 1314 PNSPFKVA--VTEGCQPSRVHAQGPGL--KEAFTNKSNVFTVVTRGAGIG 1359
            PN+  K    +     P+RV A GPGL  K         FTV T  AG G
Sbjct: 34   PNAKLKAGAPLRPRLNPARVRAYGPGLEPKGNQVGAPARFTVETFSAGRG 183

 Score =  133 bits (334), Expect = 1e-30,   Method: Compositional matrix adjust.
 Identities = 83/153 (54%), Positives = 94/153 (61%), Gaps = 2/153 (1%)
 Frame = +2

Query: 536  KSPFEVQVGPEAGMQKVRAWG-PGLHGGIV-GRSADFVVESIGSEVGTLGFAIEGPSQAK 593
            + P + + GP  G Q    W  PG  GG   GR   F VE+ G E G LGF+IEGPSQA+
Sbjct: 941  QKPLQDRGGPLXGEQDQGLWTRPGRRGGAAEGR---FTVETNG-ETGALGFSIEGPSQAQ 1108

Query: 594  IEYDDQNDGSCDVKYWPKEPGEYAVHIMCDDEDIKDSPYMAFIHPATGDYNPDLVQAYGP 653
            IE  D  DGS DV Y P  PGEYAVHI+C DEDI  SP+MA I PA  D++ + V A GP
Sbjct: 1109 IECLDNGDGSADVWYLPTMPGEYAVHILCSDEDIPKSPFMADIKPAA-DFDAEKVIAKGP 1285

Query: 654  GLEKSGCTINNPAEFIVDPKDAGSAPLKILAQD 686
            GLEKSG   N  AEF VD K AG APL I   D
Sbjct: 1286 GLEKSGVAPNKWAEFTVDTKAAGKAPLVITGMD 1384

 Score =  105 bits (262), Expect(2) = 4e-29,   Method: Compositional matrix adjust.
 Identities = 91/291 (31%), Positives = 141/291 (48%), Gaps = 13/291 (4%)
 Frame = +3

Query: 877  KAPLNVQFSSPLPGEAVKDLDIIDNYDYSHTVKYTPTQQGNMQVLVTYGGDPIPKSPFTV 936
            K  + V   +P   E   +++  ++ + +++  Y PT +G+ +V + +    I KSPFTV
Sbjct: 177  KGDVEVSILNPKGVEETCEVEFNNDRNLTYSCAYVPTMEGHYKVNILFANKVIAKSPFTV 356

Query: 937  GV-AAPLDLSKIKING--LENR-VEVGKDQEFAIDTNGAGGQGKLDVTILSP-SRK--VV 989
             V  A  D SK+  +G  LE   V   K   F +   GAG  GK+DV IL P  RK  V 
Sbjct: 357  TVEGAAGDASKVTASGPGLEKTGVVATKKTFFEVFVKGAG-NGKVDVVILDPHGRKDNVR 533

Query: 990  PCLVAPVAGRECSTAKFIPREEGLFAVDVTYDGHPVPGSPYTVEASLPPDPTKVKAHGPG 1049
            P + +          +++  ++GL +V+V + G  +P SP+ V+ +   +     A G G
Sbjct: 534  PKVQSAPDKDATYLVEYVTIDQGLHSVNVFFAGSQIPNSPFGVQVAPASNAKACYATGRG 713

Query: 1050 LE--GGLVGKPAEFTIDTKXXXXXXXXXXVEGP--CEAKIECSDNGDG--TCSVSYLPTK 1103
            ++  G  V   A+F + TK          + GP   E K +     D        Y P+K
Sbjct: 714  VQPRGVRVKDRADFYVHTKGAGDGEVAVQIIGPGGVEEKCQLKKVPDQPEVWECVYNPSK 893

Query: 1104 PGEYFVNILFEEVHIPGSPFKADIEMPFDPSKVVASGPGLEHGKVGEPGIL 1154
            PG Y +NI F + HI  SPFK ++  P+  SK+ A GPGLE G V +  +L
Sbjct: 894  PGNYIINITFGDQHISKSPFKIEVG-PYKESKIRAYGPGLEGGVVQQKAVL 1043

 Score = 43.5 bits (101), Expect(2) = 4e-29,   Method: Compositional matrix adjust.
 Identities = 30/96 (31%), Positives = 46/96 (47%), Gaps = 7/96 (7%)
 Frame = +2

Query: 1176 AKAEVSIQNNKDGTYAVTYVPLTAGMYTLTMKYGGELVPHFPAWVKVEPAIDTSGIK--A 1233
            ++A++   +N DG+  V Y+P   G Y + +    E +P  P    ++PA D    K  A
Sbjct: 1097 SQAQIECLDNGDGSADVWYLPTMPGEYAVHILCSDEDIPKSPFMADIKPAADFDAEKVIA 1276

Query: 1234 FGPGIEGKDVFREATTDFTVDSR-----PLTQVGGD 1264
             GPG+E   V      +FTVD++     PL   G D
Sbjct: 1277 KGPGLEKSGVAPNKWAEFTVDTKAAGKAPLVITGMD 1384

 Score = 85.5 bits (210), Expect(2) = 2e-26,   Method: Compositional matrix adjust.
 Identities = 74/286 (25%), Positives = 128/286 (44%), Gaps = 19/286 (6%)
 Frame = +3

Query: 1766 KGEITGTVHMPSGKKATPEIVDNKDGTVT--VRYAPTEVGLHEMHIKYRGSHIPGNPLQF 1823
            KG++  ++  P G + T E+  N D  +T    Y PT  G ++++I +    I  +P   
Sbjct: 177  KGDVEVSILNPKGVEETCEVEFNNDRNLTYSCAYVPTMEGHYKVNILFANKVIAKSPFTV 356

Query: 1824 YVNYP--NSGSVSAYGPGLVYG--VANKTATFTIVTEDAGEGGLDLAIEGPS------KA 1873
             V     ++  V+A GPGL     VA K   F +  + AG G +D+ I  P       + 
Sbjct: 357  TVEGAAGDASKVTASGPGLEKTGVVATKKTFFEVFVKGAGNGKVDVVILDPHGRKDNVRP 536

Query: 1874 EISCIDNKDGTCTVTYLPTLPGDYSILVKYNDKHIPGSPFTAKI---TGRLCCFFSDDNR 1930
            ++    +KD T  V Y+    G +S+ V +    IP SPF  ++   +    C+ +    
Sbjct: 537  KVQSAPDKDATYLVEYVTIDQGLHSVNVFFAGSQIPNSPFGVQVAPASNAKACYATGRGV 716

Query: 1931 RCSQVKLGSAADFLLDISETDLSTLTASIKAPSGRDEPCLLKRLPNNH--IGISFIPREV 1988
            +   V++   ADF +         +   I  P G +E C LK++P+        + P + 
Sbjct: 717  QPRGVRVKDRADFYVHTKGAGDGEVAVQIIGPGGVEEKCQLKKVPDQPEVWECVYNPSKP 896

Query: 1989 GEHLVSIKKNGNHVANSPVSIMVVQSEIGDARRAKV--YGQGLSEG 2032
            G ++++I     H++ SP  I     E+G  + +K+  YG GL  G
Sbjct: 897  GNYIINITFGDQHISKSPFKI-----EVGPYKESKIRAYGPGLEGG 1019

 Score = 54.7 bits (130), Expect(2) = 2e-26,   Method: Compositional matrix adjust.
 Identities = 31/79 (39%), Positives = 43/79 (54%)
 Frame = +2

Query: 2028 GLSEGRTFEMSDFIVDTRDAGYGGISLAVEGPSKVDIQTEDLEDGTCKVSYFPTVPGVYI 2087
            G +EGR      F V+T +   G +  ++EGPS+  I+  D  DG+  V Y PT+PG Y 
Sbjct: 1022 GAAEGR------FTVET-NGETGALGFSIEGPSQAQIECLDNGDGSADVWYLPTMPGEYA 1180

Query: 2088 VSTKFADEHVPGSPFTVKI 2106
            V    +DE +P SPF   I
Sbjct: 1181 VHILCSDEDIPKSPFMADI 1237

 Score =  117 bits (292), Expect = 8e-26,   Method: Compositional matrix adjust.
 Identities = 78/250 (31%), Positives = 134/250 (53%), Gaps = 14/250 (5%)
 Frame = +3

Query: 2253 AEITFDDHKNGSCGVSYIAQEPGNYEVSIKFNDEHIPDSPYLVPVIAPSDDARCLTVL-- 2310
             E+ F++ +N +   +Y+    G+Y+V+I F ++ I  SP+ V V   + DA  +T    
Sbjct: 228  CEVEFNNDRNLTYSCAYVPTMEGHYKVNILFANKVIAKSPFTVTVEGAAGDASKVTASGP 407

Query: 2311 SLQESGLKVNQPASFAIRLNGA-KGKIDAKVHSPSGAVEECHVS-ELEPDK---YAVRFI 2365
             L+++G+   +   F + + GA  GK+D  +  P G  +      +  PDK   Y V ++
Sbjct: 408  GLEKTGVVATKKTFFEVFVKGAGNGKVDVVILDPHGRKDNVRPKVQSAPDKDATYLVEYV 587

Query: 2366 PHENGIHTIDVKFNGSHVVGSPFKVRVGEPGQAGNPALVSAYGAGLETGTTGI--QSEFF 2423
              + G+H+++V F GS +  SPF V+V     A N     A G G++     +  +++F+
Sbjct: 588  TIDQGLHSVNVFFAGSQIPNSPFGVQVAP---ASNAKACYATGRGVQPRGVRVKDRADFY 758

Query: 2424 INTTQAGPGTLSVTIEGPSKVKMDCQ-----EIPEGYKVMYTPMAPGNYLIGVKYGGPNH 2478
            ++T  AG G ++V I GP  V+  CQ     + PE ++ +Y P  PGNY+I + +G   H
Sbjct: 759  VHTKGAGDGEVAVQIIGPGGVEEKCQLKKVPDQPEVWECVYNPSKPGNYIINITFGD-QH 935

Query: 2479 ISRSPFKAKV 2488
            IS+SPFK +V
Sbjct: 936  ISKSPFKIEV 965

 Score = 75.1 bits (183), Expect(2) = 2e-24,   Method: Compositional matrix adjust.
 Identities = 69/282 (24%), Positives = 123/282 (43%), Gaps = 13/282 (4%)
 Frame = +3

Query: 1955 LTASIKAPSGRDEPCLLKRLPNNHIGIS--FIPREVGEHLVSIKKNGNHVANSPVSIMVV 2012
            +  SI  P G +E C ++   + ++  S  ++P   G + V+I      +A SP ++ V 
Sbjct: 186  VEVSILNPKGVEETCEVEFNNDRNLTYSCAYVPTMEGHYKVNILFANKVIAKSPFTVTV- 362

Query: 2013 QSEIGDARRAKVYGQGLSEGRTF--EMSDFIVDTRDAGYGGISLAVEGPS------KVDI 2064
            +   GDA +    G GL +      + + F V  + AG G + + +  P       +  +
Sbjct: 363  EGAAGDASKVTASGPGLEKTGVVATKKTFFEVFVKGAGNGKVDVVILDPHGRKDNVRPKV 542

Query: 2065 QTEDLEDGTCKVSYFPTVPGVYIVSTKFADEHVPGSPFTVKISGEGRVRESI-TRTSRAP 2123
            Q+   +D T  V Y     G++ V+  FA   +P SPF V+++     +    T     P
Sbjct: 543  QSAPDKDATYLVEYVTIDQGLHSVNVFFAGSQIPNSPFGVQVAPASNAKACYATGRGVQP 722

Query: 2124 AVATVGSICDLNLKIPEINSSDMSAHVTSPSGHVTEAEI--VPMGKNSHCVRFVPQEMGV 2181
                V    D  +        +++  +  P G   + ++  VP         + P + G 
Sbjct: 723  RGVRVKDRADFYVHTKGAGDGEVAVQIIGPGGVEEKCQLKKVPDQPEVWECVYNPSKPGN 902

Query: 2182 HTVSVKYRGQHVTGSPFQFTVGPLGEGGAHKVRAGGPGLERG 2223
            + +++ +  QH++ SPF+  VGP  E    K+RA GPGLE G
Sbjct: 903  YIINITFGDQHISKSPFKIEVGPYKES---KIRAYGPGLEGG 1019

 Score = 58.5 bits (140), Expect(2) = 2e-24,   Method: Compositional matrix adjust.
 Identities = 35/96 (36%), Positives = 53/96 (55%), Gaps = 4/96 (4%)
 Frame = +2

Query: 2241 GGLSIAVEGPSKAEITFDDHKNGSCGVSYIAQEPGNYEVSIKFNDEHIPDSPYLVPVIAP 2300
            G L  ++EGPS+A+I   D+ +GS  V Y+   PG Y V I  +DE IP SP++   I P
Sbjct: 1067 GALGFSIEGPSQAQIECLDNGDGSADVWYLPTMPGEYAVHILCSDEDIPKSPFMAD-IKP 1243

Query: 2301 SDDARCLTVLS----LQESGLKVNQPASFAIRLNGA 2332
            + D     V++    L++SG+  N+ A F +    A
Sbjct: 1244 AADFDAEKVIAKGPGLEKSGVAPNKWAEFTVDTKAA 1351

 Score = 80.5 bits (197), Expect(2) = 3e-24,   Method: Compositional matrix adjust.
 Identities = 73/297 (24%), Positives = 130/297 (43%), Gaps = 14/297 (4%)
 Frame = +3

Query: 974  QGKLDVTILSPSRKVVPCLVAPVAGRECS-TAKFIPREEGLFAVDVTYDGHPVPGSPYTV 1032
            +G ++V+IL+P      C V     R  + +  ++P  EG + V++ +    +  SP+TV
Sbjct: 177  KGDVEVSILNPKGVEETCEVEFNNDRNLTYSCAYVPTMEGHYKVNILFANKVIAKSPFTV 356

Query: 1033 EAS-LPPDPTKVKAHGPGLE--GGLVGKPAEFTIDTKXXXXXXXXXXVEGP------CEA 1083
                   D +KV A GPGLE  G +  K   F +  K          +  P         
Sbjct: 357  TVEGAAGDASKVTASGPGLEKTGVVATKKTFFEVFVKGAGNGKVDVVILDPHGRKDNVRP 536

Query: 1084 KIECSDNGDGTCSVSYLPTKPGEYFVNILFEEVHIPGSPFKADIEMPFDPSKVVASGPGL 1143
            K++ + + D T  V Y+    G + VN+ F    IP SPF   +    +     A+G G+
Sbjct: 537  KVQSAPDKDATYLVEYVTIDQGLHSVNVFFAGSQIPNSPFGVQVAPASNAKACYATGRGV 716

Query: 1144 EHG--KVGEPGILCVDCSEAGPGTLGLEAVSDSGAKAEVSIQNNKDG--TYAVTYVPLTA 1199
            +    +V +     V    AG G + ++ +   G + +  ++   D    +   Y P   
Sbjct: 717  QPRGVRVKDRADFYVHTKGAGDGEVAVQIIGPGGVEEKCQLKKVPDQPEVWECVYNPSKP 896

Query: 1200 GMYTLTMKYGGELVPHFPAWVKVEPAIDTSGIKAFGPGIEGKDVFREATTDFTVDSR 1256
            G Y + + +G + +   P  ++V P  + S I+A+GPG+EG  V ++A   +   +R
Sbjct: 897  GNYIINITFGDQHISKSPFKIEVGPYKE-SKIRAYGPGLEGGVVQQKAVLLWRPTAR 1064

 Score = 52.0 bits (123), Expect(2) = 3e-24,   Method: Compositional matrix adjust.
 Identities = 38/99 (38%), Positives = 48/99 (48%), Gaps = 4/99 (4%)
 Frame = +2

Query: 1270 ITNPSGASTECFVKDNADGTYQVEYTPFEKGFHVVEVTYDDVPIPNSPFKVAVTEGC--Q 1327
            I  PS A  EC   DN DG+  V Y P   G + V +   D  IP SPF   +       
Sbjct: 1085 IEGPSQAQIECL--DNGDGSADVWYLPTMPGEYAVHILCSDEDIPKSPFMADIKPAADFD 1258

Query: 1328 PSRVHAQGPGLKEAFT--NKSNVFTVVTRGAGIGGLGIT 1364
              +V A+GPGL+++    NK   FTV T+ AG   L IT
Sbjct: 1259 AEKVIAKGPGLEKSGVAPNKWAEFTVDTKAAGKAPLVIT 1375

 Score = 72.4 bits (176), Expect(2) = 5e-23,   Method: Compositional matrix adjust.
 Identities = 56/176 (31%), Positives = 78/176 (44%)
 Frame = +3

Query: 190 DPRKPVDNAREAMQQADDWLGVPQVITPEEIIHPDVDEHSVMTYLSQFXXXXXXXXXXXX 249
           DP    DN R  +Q A D      V    E +  D   HSV  + +              
Sbjct: 504 DPHGRKDNVRPKVQSAPDKDATYLV----EYVTIDQGLHSVNVFFAGSQIPNSPFGVQVA 671

Query: 250 XXXXXXXXRAYGRGIEPTGNMVKQPAKFTVDTISAGQGDVMVFVEDPEGNKEEARVTPDS 309
                    A GRG++P G  VK  A F V T  AG G+V V +  P G +E+ ++    
Sbjct: 672 PASNAKACYATGRGVQPRGVRVKDRADFYVHTKGAGDGEVAVQIIGPGGVEEKCQLKKVP 851

Query: 310 DKNKTYSVEYLPKVTGLHKVIVLFAGQHISKSPFEVNVDKAQGDASKVTAKGPGLE 365
           D+ + +   Y P   G + + + F  QHISKSPF++ V   +   SK+ A GPGLE
Sbjct: 852 DQPEVWECVYNPSKPGNYIINITFGDQHISKSPFKIEVGPYK--ESKIRAYGPGLE 1013

 Score = 55.8 bits (133), Expect(2) = 5e-23,   Method: Compositional matrix adjust.
 Identities = 42/116 (36%), Positives = 59/116 (50%), Gaps = 2/116 (1%)
 Frame = +2

Query: 377  FDIYTAGAGVGDIGIEVEDPQGKNSVELLVEDRGNQVYRCVYKPVQPGPHVVKVSFAGDA 436
            F + T G   G +G  +E P  +  +E L  D G+      Y P  PG + V +  + + 
Sbjct: 1040 FTVETNGE-TGALGFSIEGPS-QAQIECL--DNGDGSADVWYLPTMPGEYAVHILCSDED 1207

Query: 437  IPKSPFGVQIGEACNPNACR--ASGRGLQPKGVRIRETADFKVDTKAAGSGELGVT 490
            IPKSPF   I  A + +A +  A G GL+  GV   + A+F VDTKAAG   L +T
Sbjct: 1208 IPKSPFMADIKPAADFDAEKVIAKGPGLEKSGVAPNKWAEFTVDTKAAGKAPLVIT 1375

 Score = 94.7 bits (234), Expect = 4e-19,   Method: Compositional matrix adjust.
 Identities = 91/313 (29%), Positives = 135/313 (43%), Gaps = 10/313 (3%)
 Frame = +3

Query: 1549 EGLLAVQITDQEGKPQRATVHDNKDG--TYAVTYIPDKTGRYMIGVTYGGDNIPLSPYRI 1606
            +G + V I + +G  +   V  N D   TY+  Y+P   G Y + + +    I  SP+ +
Sbjct: 177  KGDVEVSILNPKGVEETCEVEFNNDRNLTYSCAYVPTMEGHYKVNILFANKVIAKSPFTV 356

Query: 1607 RAT-QTGDASKCLATGPGIAPT-VKTGEEVGFVVDAKTAGKGKVTCVILTP----DGTEA 1660
                  GDASK  A+GPG+  T V   ++  F V  K AG GKV  VIL P    D    
Sbjct: 357  TVEGAAGDASKVTASGPGLEKTGVVATKKTFFEVFVKGAGNGKVDVVILDPHGRKDNVRP 536

Query: 1661 EADVIENEDGTYDIFYTAAKPGTYVIYVRFGGVDIPNSPFTVMVSRVPSPEPALTSRSTS 1720
            +     ++D TY + Y     G + + V F G  IPNSPF V V+      PA  +++  
Sbjct: 537  KVQSAPDKDATYLVEYVTIDQGLHSVNVFFAGSQIPNSPFGVQVA------PASNAKA-- 692

Query: 1721 TCWKLGEGRAQAVGSWVTEEAYVPVSDMNGLGFKPFDLVIPFAVRKGEITGTVHMPSG-- 1778
             C+  G G  Q  G  V + A   V    G G              GE+   +  P G  
Sbjct: 693  -CYATGRG-VQPRGVRVKDRADFYVH-TKGAG-------------DGEVAVQIIGPGGVE 824

Query: 1779 KKATPEIVDNKDGTVTVRYAPTEVGLHEMHIKYRGSHIPGNPLQFYVNYPNSGSVSAYGP 1838
            +K   + V ++       Y P++ G + ++I +   HI  +P +  V       + AYGP
Sbjct: 825  EKCQLKKVPDQPEVWECVYNPSKPGNYIINITFGDQHISKSPFKIEVGPYKESKIRAYGP 1004

Query: 1839 GLVYGVANKTATF 1851
            GL  GV  + A  
Sbjct: 1005 GLEGGVVQQKAVL 1043

 Score = 86.3 bits (212), Expect = 1e-16,   Method: Compositional matrix adjust.
 Identities = 50/103 (48%), Positives = 60/103 (58%), Gaps = 2/103 (1%)
 Frame = +2

Query: 1048 PGLEGGLVGKPAEFTIDTKXXXXXXXXXXVEGPCEAKIECSDNGDGTCSVSYLPTKPGEY 1107
            PG  GG       FT++T           +EGP +A+IEC DNGDG+  V YLPT PGEY
Sbjct: 1007 PGRRGGAA--EGRFTVETNGETGALGFS-IEGPSQAQIECLDNGDGSADVWYLPTMPGEY 1177

Query: 1108 FVNILFEEVHIPGSPFKADIE--MPFDPSKVVASGPGLEHGKV 1148
             V+IL  +  IP SPF ADI+    FD  KV+A GPGLE   V
Sbjct: 1178 AVHILCSDEDIPKSPFMADIKPAADFDAEKVIAKGPGLEKSGV 1306

 Score = 79.7 bits (195), Expect = 1e-14,   Method: Compositional matrix adjust.
 Identities = 83/287 (28%), Positives = 121/287 (42%), Gaps = 14/287 (4%)
 Frame = +3

Query: 1645 KGKVTCVILTPDGTEAEADVIENEDG--TYDIFYTAAKPGTYVIYVRFGGVDIPNSPFTV 1702
            KG V   IL P G E   +V  N D   TY   Y     G Y + + F    I  SPFTV
Sbjct: 177  KGDVEVSILNPKGVEETCEVEFNNDRNLTYSCAYVPTMEGHYKVNILFANKVIAKSPFTV 356

Query: 1703 MVSRVPSPEPALTSRSTSTCWKLGEGRAQAVGSWVTEEAYVPVSDMNGLGFKPFDLVIPF 1762
             V         +T+         G G  +  G   T++ +  V  + G G    D+VI  
Sbjct: 357  TVEGAAGDASKVTAS--------GPG-LEKTGVVATKKTFFEVF-VKGAGNGKVDVVI-- 500

Query: 1763 AVRKGEITGTVHMPSGKK--ATPEI--VDNKDGTVTVRYAPTEVGLHEMHIKYRGSHIPG 1818
                         P G+K    P++    +KD T  V Y   + GLH +++ + GS IP 
Sbjct: 501  -----------LDPHGRKDNVRPKVQSAPDKDATYLVEYVTIDQGLHSVNVFFAGSQIPN 647

Query: 1819 NPLQFYVNYPNSGSVSAYGPGL---VYGVANK-TATFTIVTEDAGEGGLDLAIEGPSKAE 1874
            +P    V  P S + + Y  G      GV  K  A F + T+ AG+G + + I GP   E
Sbjct: 648  SPFGVQVA-PASNAKACYATGRGVQPRGVRVKDRADFYVHTKGAGDGEVAVQIIGPGGVE 824

Query: 1875 ISC----IDNKDGTCTVTYLPTLPGDYSILVKYNDKHIPGSPFTAKI 1917
              C    + ++       Y P+ PG+Y I + + D+HI  SPF  ++
Sbjct: 825  EKCQLKKVPDQPEVWECVYNPSKPGNYIINITFGDQHISKSPFKIEV 965

 Score = 78.6 bits (192), Expect = 3e-14,   Method: Compositional matrix adjust.
 Identities = 77/300 (25%), Positives = 124/300 (41%), Gaps = 14/300 (4%)
 Frame = +3

Query: 2333 KGKIDAKVHSPSGAVEECHVSELEPDK---YAVRFIPHENGIHTIDVKFNGSHVVGSPFK 2389
            KG ++  + +P G  E C V E   D+   Y+  ++P   G + +++ F    +  SPF 
Sbjct: 177  KGDVEVSILNPKGVEETCEV-EFNNDRNLTYSCAYVPTMEGHYKVNILFANKVIAKSPFT 353

Query: 2390 VRVGEPGQAGNPALVSAYGAGLE-TGTTGIQSEFF-INTTQAGPGTLSVTIEGP----SK 2443
            V V   G AG+ + V+A G GLE TG    +  FF +    AG G + V I  P      
Sbjct: 354  VTV--EGAAGDASKVTASGPGLEKTGVVATKKTFFEVFVKGAGNGKVDVVILDPHGRKDN 527

Query: 2444 VKMDCQEIPEG---YKVMYTPMAPGNYLIGVKYGGPNHISRSPFKAKVTGQRLVSPGSAN 2500
            V+   Q  P+    Y V Y  +  G + + V + G + I  SPF  +V            
Sbjct: 528  VRPKVQSAPDKDATYLVEYVTIDQGLHSVNVFFAG-SQIPNSPFGVQVA----------- 671

Query: 2501 ETSSILVESVTRSSTETCYSAIPKSSSDASKVTSKGAGLSKAFVGQKSSFLVDCSKAGSN 2560
                                  P S++ A   T +G       V  ++ F V    AG  
Sbjct: 672  ----------------------PASNAKACYATGRGVQPRGVRVKDRADFYVHTKGAGDG 785

Query: 2561 MLLIGVHGPTTPCEEVSMKHVGKQQ--YNVTYVVKERGDYVLAVKWGEEHIPGSPFHVTV 2618
             + + + GP    E+  +K V  Q   +   Y   + G+Y++ + +G++HI  SPF + V
Sbjct: 786  EVAVQIIGPGGVEEKCQLKKVPDQPEVWECVYNPSKPGNYIINITFGDQHISKSPFKIEV 965

 Score = 77.4 bits (189), Expect = 7e-14,   Method: Compositional matrix adjust.
 Identities = 51/113 (45%), Positives = 62/113 (54%), Gaps = 4/113 (3%)
 Frame = +2

Query: 1349 FTVVTRGAGIGGLGITVEGPSESKINCRDNKDGSCSAEYIPFAPGDYDVNITYGGVHIPG 1408
            FTV T G   G LG ++EGPS+++I C DN DGS    Y+P  PG+Y V+I      IP 
Sbjct: 1040 FTVETNGE-TGALGFSIEGPSQAQIECLDNGDGSADVWYLPTMPGEYAVHILCSDEDIPK 1216

Query: 1409 SPFRV---PSKDVVDPSKVKIAGPGLS-SCVRACIPQSFTVDSSKAGLAPLEV 1457
            SPF     P+ D  D  KV   GPGL  S V       FTVD+  AG APL +
Sbjct: 1217 SPFMADIKPAAD-FDAEKVIAKGPGLEKSGVAPNKWAEFTVDTKAAGKAPLVI 1372

 Score = 75.1 bits (183), Expect = 4e-13,   Method: Compositional matrix adjust.
 Identities = 38/88 (43%), Positives = 53/88 (60%), Gaps = 2/88 (2%)
 Frame = +2

Query: 797  FDIIHNANDTFTVKYVPPAPGRYTIKVLFASQEIPASPFRVKVDPS--HDASKVKAEGPG 854
             + + N + +  V Y+P  PG Y + +L + ++IP SPF   + P+   DA KV A+GPG
Sbjct: 1109 IECLDNGDGSADVWYLPTMPGEYAVHILCSDEDIPKSPFMADIKPAADFDAEKVIAKGPG 1288

Query: 855  LSKAGVENGKPTHFTVHTKGAGKAPLNV 882
            L K+GV   K   FTV TK AGKAPL +
Sbjct: 1289 LEKSGVAPNKWAEFTVDTKAAGKAPLVI 1372

 Score = 73.6 bits (179), Expect = 1e-12,   Method: Compositional matrix adjust.
 Identities = 67/268 (25%), Positives = 120/268 (44%), Gaps = 20/268 (7%)
 Frame = +3

Query: 2050 GGISLAVEGPSKVD----IQTEDLEDGTCKVSYFPTVPGVYIVSTKFADEHVPGSPFTVK 2105
            G + +++  P  V+    ++  +  + T   +Y PT+ G Y V+  FA++ +  SPFTV 
Sbjct: 180  GDVEVSILNPKGVEETCEVEFNNDRNLTYSCAYVPTMEGHYKVNILFANKVIAKSPFTVT 359

Query: 2106 ISGEGRVRESITRTSRAPAVATVGSICD----LNLKIPEINSSDMSAHVTSPSGHVT--- 2158
            +  EG   ++   T+  P +   G +        + +    +  +   +  P G      
Sbjct: 360  V--EGAAGDASKVTASGPGLEKTGVVATKKTFFEVFVKGAGNGKVDVVILDPHGRKDNVR 533

Query: 2159 -EAEIVPMGKNSHCVRFVPQEMGVHTVSVKYRGQHVTGSPFQFTVGPLGEGGAHKVRAGG 2217
             + +  P    ++ V +V  + G+H+V+V + G  +  SPF   V P     A    A G
Sbjct: 534  PKVQSAPDKDATYLVEYVTIDQGLHSVNVFFAGSQIPNSPFGVQVAPASN--AKACYATG 707

Query: 2218 PGLE-RG-EAGIPAEFSIWTREAGAGGLSIAVEGPSKAEITF------DDHKNGSCGVSY 2269
             G++ RG      A+F + T+ AG G +++ + GP   E         D  +   C   Y
Sbjct: 708  RGVQPRGVRVKDRADFYVHTKGAGDGEVAVQIIGPGGVEEKCQLKKVPDQPEVWEC--VY 881

Query: 2270 IAQEPGNYEVSIKFNDEHIPDSPYLVPV 2297
               +PGNY ++I F D+HI  SP+ + V
Sbjct: 882  NPSKPGNYIINITFGDQHISKSPFKIEV 965

 Score = 70.9 bits (172), Expect = 7e-12,   Method: Compositional matrix adjust.
 Identities = 39/81 (48%), Positives = 52/81 (64%), Gaps = 1/81 (1%)
 Frame = +2

Query: 1838 PGLVYGVANKTATFTIVTEDAGE-GGLDLAIEGPSKAEISCIDNKDGTCTVTYLPTLPGD 1896
            PG   G A     FT+ T   GE G L  +IEGPS+A+I C+DN DG+  V YLPT+PG+
Sbjct: 1007 PGRRGGAAE--GRFTVETN--GETGALGFSIEGPSQAQIECLDNGDGSADVWYLPTMPGE 1174

Query: 1897 YSILVKYNDKHIPGSPFTAKI 1917
            Y++ +  +D+ IP SPF A I
Sbjct: 1175 YAVHILCSDEDIPKSPFMADI 1237

 Score = 53.9 bits (128), Expect = 8e-07,   Method: Compositional matrix adjust.
 Identities = 39/111 (35%), Positives = 59/111 (53%), Gaps = 1/111 (0%)
 Frame = +2

Query: 276  KFTVDTISAGQGDVMVFVEDPEGNKEEARVTPDSDKNKTYSVEYLPKVTGLHKVIVLFAG 335
            +FTV+T +   G +   +E P     +A++    + + +  V YLP + G + V +L + 
Sbjct: 1037 RFTVET-NGETGALGFSIEGPS----QAQIECLDNGDGSADVWYLPTMPGEYAVHILCSD 1201

Query: 336  QHISKSPFEVNVD-KAQGDASKVTAKGPGLETTGNIANKPTYFDIYTAGAG 385
            + I KSPF  ++   A  DA KV AKGPGLE +G   NK   F + T  AG
Sbjct: 1202 EDIPKSPFMADIKPAADFDAEKVIAKGPGLEKSGVAPNKWAEFTVDTKAAG 1354

 Score = 49.3 bits (116), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 37/122 (30%), Positives = 55/122 (45%), Gaps = 12/122 (9%)
 Frame = +2

Query: 1547 AGEGLLAVQITDQEGK-------PQRATVH--DNKDGTYAVTYIPDKTGRYMIGVTYGGD 1597
            A EG   V+   + G        P +A +   DN DG+  V Y+P   G Y + +    +
Sbjct: 1025 AAEGRFTVETNGETGALGFSIEGPSQAQIECLDNGDGSADVWYLPTMPGEYAVHILCSDE 1204

Query: 1598 NIPLSPYR--IRATQTGDASKCLATGPGIAPT-VKTGEEVGFVVDAKTAGKGKVTCVILT 1654
            +IP SP+   I+     DA K +A GPG+  + V   +   F VD K AGK  +    + 
Sbjct: 1205 DIPKSPFMADIKPAADFDAEKVIAKGPGLEKSGVAPNKWAEFTVDTKAAGKAPLVITGMD 1384

Query: 1655 PD 1656
             D
Sbjct: 1385 TD 1390

 Score = 43.5 bits (101), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 37/102 (36%), Positives = 52/102 (50%), Gaps = 5/102 (4%)
 Frame = +2

Query: 1767 GEITGTVHMPSGKKATPEIVDNKDGTVTVRYAPTEVGLHEMHIKYRGSHIPGNPLQFYVN 1826
            G +  ++  PS  +A  E +DN DG+  V Y PT  G + +HI      IP +P    + 
Sbjct: 1067 GALGFSIEGPS--QAQIECLDNGDGSADVWYLPTMPGEYAVHILCSDEDIPKSPFMADIK 1240

Query: 1827 YP---NSGSVSAYGPGL-VYGVA-NKTATFTIVTEDAGEGGL 1863
                 ++  V A GPGL   GVA NK A FT+ T+ AG+  L
Sbjct: 1241 PAADFDAEKVIAKGPGLEKSGVAPNKWAEFTVDTKAAGKAPL 1366

 Score = 42.7 bits (99), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 25/83 (30%), Positives = 42/83 (50%), Gaps = 2/83 (2%)
 Frame = +2

Query: 694  IQMKSRMDGTYACSYTPLKAIKHTIAVVWGGVNIPHSPYRVNIGQGSH--PQKVKVFGPG 751
            I+     DG+    Y P    ++ + ++    +IP SP+  +I   +    +KV   GPG
Sbjct: 1109 IECLDNGDGSADVWYLPTMPGEYAVHILCSDEDIPKSPFMADIKPAADFDAEKVIAKGPG 1288

Query: 752  VERSGLKANEPTHFTVDCTEAGE 774
            +E+SG+  N+   FTVD   AG+
Sbjct: 1289 LEKSGVAPNKWAEFTVDTKAAGK 1357

 Score = 38.9 bits (89), Expect = 0.030,   Method: Compositional matrix adjust.
 Identities = 29/91 (31%), Positives = 45/91 (49%), Gaps = 4/91 (4%)
 Frame = +2

Query: 2159 EAEIVPMGKNSHCVRFVPQEMGVHTVSVKYRGQHVTGSPFQFTVGPLGEGGAHKVRAGGP 2218
            + E +  G  S  V ++P   G + V +    + +  SPF   + P  +  A KV A GP
Sbjct: 1106 QIECLDNGDGSADVWYLPTMPGEYAVHILCSDEDIPKSPFMADIKPAADFDAEKVIAKGP 1285

Query: 2219 GLERGEAGIP----AEFSIWTREAGAGGLSI 2245
            GLE+  +G+     AEF++ T+ AG   L I
Sbjct: 1286 GLEK--SGVAPNKWAEFTVDTKAAGKAPLVI 1372

 Score = 38.5 bits (88), Expect = 0.038,   Method: Composition-based stats.
 Identities = 20/55 (36%), Positives = 30/55 (54%)
 Frame = +1

Query: 832 ASPFRVKVDPSHDASKVKAEGPGLSKAGVENGKPTHFTVHTKGAGKAPLNVQFSS 886
            +P R +++P+    +V+A GPGL   G + G P  FTV T  AG+      FS+
Sbjct: 55  GAPLRPRLNPA----RVRAYGPGLEPKGNQVGAPARFTVETFSAGRGMWRCLFST 207

 Score = 37.0 bits (84), Expect = 0.11,   Method: Composition-based stats.
 Identities = 20/44 (45%), Positives = 27/44 (61%), Gaps = 4/44 (9%)
 Frame = +1

Query: 1026 PGSPYTVEASLPP--DPTKVKAHGPGLE--GGLVGKPAEFTIDT 1065
            P +     A L P  +P +V+A+GPGLE  G  VG PA FT++T
Sbjct: 34   PNAKLKAGAPLRPRLNPARVRAYGPGLEPKGNQVGAPARFTVET 165

 Score = 35.0 bits (79), Expect = 0.44,   Method: Composition-based stats.
 Identities = 14/35 (40%), Positives = 21/35 (60%)
 Frame = +1

Query: 741 HPQKVKVFGPGVERSGLKANEPTHFTVDCTEAGEG 775
           +P +V+ +GPG+E  G +   P  FTV+   AG G
Sbjct: 79  NPARVRAYGPGLEPKGNQVGAPARFTVETFSAGRG 183
>17351
          Length = 654

 Score =  234 bits (597), Expect = 3e-61,   Method: Compositional matrix adjust.
 Identities = 114/216 (52%), Positives = 150/216 (69%)
 Frame = -1

Query: 2141 INSSDMSAHVTSPSGHVTEAEIVPMGKNSHCVRFVPQEMGVHTVSVKYRGQHVTGSPFQF 2200
            I S D++A VTSPS    +AEI  +    + V FVP+E+GVHTVSV+Y   H+ GSPFQF
Sbjct: 654  ITSFDLAACVTSPSNVTEDAEIQEIEDGLYSVHFVPKELGVHTVSVRYSEMHIPGSPFQF 475

Query: 2201 TVGPLGEGGAHKVRAGGPGLERGEAGIPAEFSIWTREAGAGGLSIAVEGPSKAEITFDDH 2260
            TVGPL + G+H V+AGG GLERG  G PAEF++WTREAG G L+I+VEGPSKA+I F D 
Sbjct: 474  TVGPLRDSGSHLVKAGGSGLERGVVGEPAEFNVWTREAGGGSLAISVEGPSKADIEFKDR 295

Query: 2261 KNGSCGVSYIAQEPGNYEVSIKFNDEHIPDSPYLVPVIAPSDDARCLTVLSLQESGLKVN 2320
            K+GSC VSY   EPG Y V +KFND HIPDSP+ V +   + DA  L V    +  ++ +
Sbjct: 294  KDGSCDVSYKVTEPGEYRVGLKFNDRHIPDSPFKVYISPDAGDAHKLEVQQFPQGNIQAD 115

Query: 2321 QPASFAIRLNGAKGKIDAKVHSPSGAVEECHVSELE 2356
             P  F +R NGAKG++DAK+ +PSG  ++C +  ++
Sbjct: 114  APYQFMVRKNGAKGELDAKIVAPSGTDDDCFIQAID 7

 Score =  132 bits (331), Expect = 2e-30,   Method: Compositional matrix adjust.
 Identities = 77/211 (36%), Positives = 117/211 (55%), Gaps = 4/211 (1%)
 Frame = -1

Query: 1768 EITGTVHMPSGKKATPEIVDNKDGTVTVRYAPTEVGLHEMHIKYRGSHIPGNPLQFYVN- 1826
            ++   V  PS      EI + +DG  +V + P E+G+H + ++Y   HIPG+P QF V  
Sbjct: 642  DLAACVTSPSNVTEDAEIQEIEDGLYSVHFVPKELGVHTVSVRYSEMHIPGSPFQFTVGP 463

Query: 1827 YPNSGS--VSAYGPGLVYGVANKTATFTIVTEDAGEGGLDLAIEGPSKAEISCIDNKDGT 1884
              +SGS  V A G GL  GV  + A F + T +AG G L +++EGPSKA+I   D KDG+
Sbjct: 462  LRDSGSHLVKAGGSGLERGVVGEPAEFNVWTREAGGGSLAISVEGPSKADIEFKDRKDGS 283

Query: 1885 CTVTYLPTLPGDYSILVKYNDKHIPGSPFTAKITGRLCCFFSDDNRRCSQVKLGSAADFL 1944
            C V+Y  T PG+Y + +K+ND+HIP SPF   I+         + ++  Q  + + A + 
Sbjct: 282  CDVSYKVTEPGEYRVGLKFNDRHIPDSPFKVYISPDAGDAHKLEVQQFPQGNIQADAPYQ 103

Query: 1945 LDISETDLS-TLTASIKAPSGRDEPCLLKRL 1974
              + +      L A I APSG D+ C ++ +
Sbjct: 102  FMVRKNGAKGELDAKIVAPSGTDDDCFIQAI 10

 Score =  125 bits (314), Expect = 2e-28,   Method: Compositional matrix adjust.
 Identities = 80/215 (37%), Positives = 114/215 (53%), Gaps = 3/215 (1%)
 Frame = -1

Query: 484 SGELGVTVKGPKGLEELVKQKGFLDGVYSFEYYPSTPGKYSVAVTWGGHHIPKSPFEVQV 543
           S +L   V  P  + E  + +   DG+YS  + P   G ++V+V +   HIP SPF+  V
Sbjct: 648 SFDLAACVTSPSNVTEDAEIQEIEDGLYSVHFVPKELGVHTVSVRYSEMHIPGSPFQFTV 469

Query: 544 GP--EAGMQKVRAWGPGLHGGIVGRSADFVVESIGSEVGTLGFAIEGPSQAKIEYDDQND 601
           GP  ++G   V+A G GL  G+VG  A+F V +  +  G+L  ++EGPS+A IE+ D+ D
Sbjct: 468 GPLRDSGSHLVKAGGSGLERGVVGEPAEFNVWTREAGGGSLAISVEGPSKADIEFKDRKD 289

Query: 602 GSCDVKYWPKEPGEYAVHIMCDDEDIKDSPYMAFIHPATGDYNPDLVQAYGPGLEKSGCT 661
           GSCDV Y   EPGEY V +  +D  I DSP+  +I P  GD +   VQ +  G       
Sbjct: 288 GSCDVSYKVTEPGEYRVGLKFNDRHIPDSPFKVYISPDAGDAHKLEVQQFPQG----NIQ 121

Query: 662 INNPAEFIVDPKDA-GSAPLKILAQDGEGQPIDIQ 695
            + P +F+V    A G    KI+A  G      IQ
Sbjct: 120 ADAPYQFMVRKNGAKGELDAKIVAPSGTDDDCFIQ 16

 Score =  111 bits (277), Expect = 5e-24,   Method: Compositional matrix adjust.
 Identities = 60/153 (39%), Positives = 87/153 (56%)
 Frame = -1

Query: 1955 LTASIKAPSGRDEPCLLKRLPNNHIGISFIPREVGEHLVSIKKNGNHVANSPVSIMVVQS 2014
            L A + +PS   E   ++ + +    + F+P+E+G H VS++ +  H+  SP    V   
Sbjct: 639  LAACVTSPSNVTEDAEIQEIEDGLYSVHFVPKELGVHTVSVRYSEMHIPGSPFQFTVGPL 460

Query: 2015 EIGDARRAKVYGQGLSEGRTFEMSDFIVDTRDAGYGGISLAVEGPSKVDIQTEDLEDGTC 2074
                +   K  G GL  G   E ++F V TR+AG G ++++VEGPSK DI+ +D +DG+C
Sbjct: 459  RDSGSHLVKAGGSGLERGVVGEPAEFNVWTREAGGGSLAISVEGPSKADIEFKDRKDGSC 280

Query: 2075 KVSYFPTVPGVYIVSTKFADEHVPGSPFTVKIS 2107
             VSY  T PG Y V  KF D H+P SPF V IS
Sbjct: 279  DVSYKVTEPGEYRVGLKFNDRHIPDSPFKVYIS 181

 Score =  110 bits (274), Expect = 9e-24,   Method: Compositional matrix adjust.
 Identities = 71/202 (35%), Positives = 104/202 (51%), Gaps = 3/202 (1%)
 Frame = -1

Query: 1266 IKAQITNPSGASTECFVKDNADGTYQVEYTPFEKGFHVVEVTYDDVPIPNSPFKVAV--T 1323
            + A +T+PS  + +  +++  DG Y V + P E G H V V Y ++ IP SPF+  V   
Sbjct: 639  LAACVTSPSNVTEDAEIQEIEDGLYSVHFVPKELGVHTVSVRYSEMHIPGSPFQFTVGPL 460

Query: 1324 EGCQPSRVHAQGPGLKEAFTNKSNVFTVVTRGAGIGGLGITVEGPSESKINCRDNKDGSC 1383
                   V A G GL+     +   F V TR AG G L I+VEGPS++ I  +D KDGSC
Sbjct: 459  RDSGSHLVKAGGSGLERGVVGEPAEFNVWTREAGGGSLAISVEGPSKADIEFKDRKDGSC 280

Query: 1384 SAEYIPFAPGDYDVNITYGGVHIPGSPFRV-PSKDVVDPSKVKIAGPGLSSCVRACIPQS 1442
               Y    PG+Y V + +   HIP SPF+V  S D  D  K+++      + ++A  P  
Sbjct: 279  DVSYKVTEPGEYRVGLKFNDRHIPDSPFKVYISPDAGDAHKLEVQQFPQGN-IQADAPYQ 103

Query: 1443 FTVDSSKAGLAPLEVRVLGPRG 1464
            F V  + A    L+ +++ P G
Sbjct: 102  FMVRKNGAK-GELDAKIVAPSG 40

 Score =  108 bits (271), Expect = 2e-23,   Method: Compositional matrix adjust.
 Identities = 60/153 (39%), Positives = 92/153 (60%), Gaps = 1/153 (0%)
 Frame = -1

Query: 2338 AKVHSPSGAVEECHVSELEPDKYAVRFIPHENGIHTIDVKFNGSHVVGSPFKVRVGEPGQ 2397
            A V SPS   E+  + E+E   Y+V F+P E G+HT+ V+++  H+ GSPF+  VG P +
Sbjct: 633  ACVTSPSNVTEDAEIQEIEDGLYSVHFVPKELGVHTVSVRYSEMHIPGSPFQFTVG-PLR 457

Query: 2398 AGNPALVSAYGAGLETGTTGIQSEFFINTTQAGPGTLSVTIEGPSKVKMDCQEIPEGY-K 2456
                 LV A G+GLE G  G  +EF + T +AG G+L++++EGPSK  ++ ++  +G   
Sbjct: 456  DSGSHLVKAGGSGLERGVVGEPAEFNVWTREAGGGSLAISVEGPSKADIEFKDRKDGSCD 277

Query: 2457 VMYTPMAPGNYLIGVKYGGPNHISRSPFKAKVT 2489
            V Y    PG Y +G+K+    HI  SPFK  ++
Sbjct: 276  VSYKVTEPGEYRVGLKFND-RHIPDSPFKVYIS 181

 Score = 99.4 bits (246), Expect = 2e-20,   Method: Compositional matrix adjust.
 Identities = 56/127 (44%), Positives = 71/127 (55%), Gaps = 2/127 (1%)
 Frame = -1

Query: 1003 TAKFIPREEGLFAVDVTYDGHPVPGSPYTVEASLPPDPTK--VKAHGPGLEGGLVGKPAE 1060
            +  F+P+E G+  V V Y    +PGSP+        D     VKA G GLE G+VG+PAE
Sbjct: 564  SVHFVPKELGVHTVSVRYSEMHIPGSPFQFTVGPLRDSGSHLVKAGGSGLERGVVGEPAE 385

Query: 1061 FTIDTKXXXXXXXXXXVEGPCEAKIECSDNGDGTCSVSYLPTKPGEYFVNILFEEVHIPG 1120
            F + T+          VEGP +A IE  D  DG+C VSY  T+PGEY V + F + HIP 
Sbjct: 384  FNVWTREAGGGSLAISVEGPSKADIEFKDRKDGSCDVSYKVTEPGEYRVGLKFNDRHIPD 205

Query: 1121 SPFKADI 1127
            SPFK  I
Sbjct: 204  SPFKVYI 184

 Score = 83.6 bits (205), Expect = 9e-16,   Method: Compositional matrix adjust.
 Identities = 68/210 (32%), Positives = 105/210 (50%), Gaps = 5/210 (2%)
 Frame = -1

Query: 1455 LEVRVLGPRGLVEPVNVVDNGDGTHTVTYTPSQEGPYIVSVKYADEEIPRSPFKVKVLPT 1514
            L   V  P  + E   + +  DG ++V + P + G + VSV+Y++  IP SPF+  V P 
Sbjct: 639  LAACVTSPSNVTEDAEIQEIEDGLYSVHFVPKELGVHTVSVRYSEMHIPGSPFQFTVGPL 460

Query: 1515 YDASK--VTASGPGLSAYGVPASLPVEFAIDARDAGEGLLAVQITDQEGKPQRATVH--D 1570
             D+    V A G GL   GV    P EF +  R+AG G LA+ +   EG P +A +   D
Sbjct: 459  RDSGSHLVKAGGSGLER-GVVGE-PAEFNVWTREAGGGSLAISV---EG-PSKADIEFKD 298

Query: 1571 NKDGTYAVTYIPDKTGRYMIGVTYGGDNIPLSPYRIRAT-QTGDASKCLATGPGIAPTVK 1629
             KDG+  V+Y   + G Y +G+ +   +IP SP+++  +   GDA K L         ++
Sbjct: 297  RKDGSCDVSYKVTEPGEYRVGLKFNDRHIPDSPFKVYISPDAGDAHK-LEVQQFPQGNIQ 121

Query: 1630 TGEEVGFVVDAKTAGKGKVTCVILTPDGTE 1659
                  F+V  K   KG++   I+ P GT+
Sbjct: 120  ADAPYQFMV-RKNGAKGELDAKIVAPSGTD 34

 Score = 83.2 bits (204), Expect = 1e-15,   Method: Compositional matrix adjust.
 Identities = 61/208 (29%), Positives = 99/208 (47%), Gaps = 4/208 (1%)
 Frame = -1

Query: 796 DFDIIHNANDTFTVKYVPPAPGRYTIKVLFASQEIPASPFRVKVDPSHDASK--VKAEGP 853
           D +I    +  ++V +VP   G +T+ V ++   IP SPF+  V P  D+    VKA G 
Sbjct: 600 DAEIQEIEDGLYSVHFVPKELGVHTVSVRYSEMHIPGSPFQFTVGPLRDSGSHLVKAGGS 421

Query: 854 GLSKAGVENGKPTHFTVHTKGAGKAPLNVQFSSPLPGEAVKDLDIIDNYDYSHTVKYTPT 913
           GL +  V  G+P  F V T+ AG   L +    P    +  D++  D  D S  V Y  T
Sbjct: 420 GLERGVV--GEPAEFNVWTREAGGGSLAISVEGP----SKADIEFKDRKDGSCDVSYKVT 259

Query: 914 QQGNMQVLVTYGGDPIPKSPFTVGVAAPL-DLSKIKINGL-ENRVEVGKDQEFAIDTNGA 971
           + G  +V + +    IP SPF V ++    D  K+++    +  ++     +F +  NGA
Sbjct: 258 EPGEYRVGLKFNDRHIPDSPFKVYISPDAGDAHKLEVQQFPQGNIQADAPYQFMVRKNGA 79

Query: 972 GGQGKLDVTILSPSRKVVPCLVAPVAGR 999
             +G+LD  I++PS     C +  + G 
Sbjct: 78  --KGELDAKIVAPSGTDDDCFIQAIDGE 1

 Score = 79.7 bits (195), Expect = 2e-14,   Method: Compositional matrix adjust.
 Identities = 64/198 (32%), Positives = 99/198 (50%), Gaps = 6/198 (3%)
 Frame = -1

Query: 1092 DGTCSVSYLPTKPGEYFVNILFEEVHIPGSPFKADIEMPFDPSK--VVASGPGLEHGKVG 1149
            DG  SV ++P + G + V++ + E+HIPGSPF+  +    D     V A G GLE G VG
Sbjct: 576  DGLYSVHFVPKELGVHTVSVRYSEMHIPGSPFQFTVGPLRDSGSHLVKAGGSGLERGVVG 397

Query: 1150 EPGILCVDCSEAGPGTLGLEAVSDSG-AKAEVSIQNNKDGTYAVTYVPLTAGMYTLTMKY 1208
            EP    V   EAG G+L   A+S  G +KA++  ++ KDG+  V+Y     G Y + +K+
Sbjct: 396  EPAEFNVWTREAGGGSL---AISVEGPSKADIEFKDRKDGSCDVSYKVTEPGEYRVGLKF 226

Query: 1209 GGELVPHFPAWVKVEPAIDTSG---IKAFGPGIEGKDVFREATTDFTVDSRPLTQVGGDH 1265
                +P  P  V + P    +    ++ F  G    ++  +A   F V  R     G   
Sbjct: 225  NDRHIPDSPFKVYISPDAGDAHKLEVQQFPQG----NIQADAPYQFMV--RKNGAKG--E 70

Query: 1266 IKAQITNPSGASTECFVK 1283
            + A+I  PSG   +CF++
Sbjct: 69   LDAKIVAPSGTDDDCFIQ 16

 Score = 78.6 bits (192), Expect = 3e-14,   Method: Compositional matrix adjust.
 Identities = 67/216 (31%), Positives = 103/216 (47%), Gaps = 4/216 (1%)
 Frame = -1

Query: 288 DVMVFVEDPEGNKEEARVTPDSDKNKTYSVEYLPKVTGLHKVIVLFAGQHISKSPFEVNV 347
           D+   V  P    E+A +    D    YSV ++PK  G+H V V ++  HI  SPF+  V
Sbjct: 642 DLAACVTSPSNVTEDAEIQEIEDG--LYSVHFVPKELGVHTVSVRYSEMHIPGSPFQFTV 469

Query: 348 DKAQGDASK-VTAKGPGLETTGNIANKPTYFDIYTAGAGVGDIGIEVEDPQGKNSVELLV 406
              +   S  V A G GLE    +  +P  F+++T  AG G + I VE P   +  ++  
Sbjct: 468 GPLRDSGSHLVKAGGSGLER--GVVGEPAEFNVWTREAGGGSLAISVEGP---SKADIEF 304

Query: 407 EDRGNQVYRCVYKPVQPGPHVVKVSFAGDAIPKSPFGVQIGEACNPNACRASGRGLQ--P 464
           +DR +      YK  +PG + V + F    IP SPF V I    +P+A  A    +Q  P
Sbjct: 303 KDRKDGSCDVSYKVTEPGEYRVGLKFNDRHIPDSPFKVYI----SPDAGDAHKLEVQQFP 136

Query: 465 KGVRIRETADFKVDTKAAGS-GELGVTVKGPKGLEE 499
           +G  I+  A ++   +  G+ GEL   +  P G ++
Sbjct: 135 QG-NIQADAPYQFMVRKNGAKGELDAKIVAPSGTDD 31

 Score = 74.7 bits (182), Expect = 5e-13,   Method: Compositional matrix adjust.
 Identities = 55/200 (27%), Positives = 96/200 (48%), Gaps = 5/200 (2%)
 Frame = -1

Query: 693 DIQMKSRMDGTYACSYTPLKAIKHTIAVVWGGVNIPHSPYRVNIG----QGSHPQKVKVF 748
           D +++   DG Y+  + P +   HT++V +  ++IP SP++  +G     GSH   VK  
Sbjct: 600 DAEIQEIEDGLYSVHFVPKELGVHTVSVRYSEMHIPGSPFQFTVGPLRDSGSH--LVKAG 427

Query: 749 GPGVERSGLKANEPTHFTVDCTEAGEGDVSVGIKCDARVLSDDEEDVDFDIIHNANDTFT 808
           G G+ER  +   EP  F V   EAG G +++ ++  ++         D +     + +  
Sbjct: 426 GSGLERGVV--GEPAEFNVWTREAGGGSLAISVEGPSK--------ADIEFKDRKDGSCD 277

Query: 809 VKYVPPAPGRYTIKVLFASQEIPASPFRVKVDP-SHDASKVKAEGPGLSKAGVENGKPTH 867
           V Y    PG Y + + F  + IP SPF+V + P + DA K++ +     +  ++   P  
Sbjct: 276 VSYKVTEPGEYRVGLKFNDRHIPDSPFKVYISPDAGDAHKLEVQ--QFPQGNIQADAPYQ 103

Query: 868 FTVHTKGAGKAPLNVQFSSP 887
           F V   GA K  L+ +  +P
Sbjct: 102 FMVRKNGA-KGELDAKIVAP 46

 Score = 70.9 bits (172), Expect = 7e-12,   Method: Compositional matrix adjust.
 Identities = 46/156 (29%), Positives = 79/156 (50%), Gaps = 2/156 (1%)
 Frame = -1

Query: 1552 LAVQITDQEGKPQRATVHDNKDGTYAVTYIPDKTGRYMIGVTYGGDNIPLSPYRIRATQT 1611
            LA  +T      + A + + +DG Y+V ++P + G + + V Y   +IP SP++      
Sbjct: 639  LAACVTSPSNVTEDAEIQEIEDGLYSVHFVPKELGVHTVSVRYSEMHIPGSPFQFTVGPL 460

Query: 1612 GDASKCL--ATGPGIAPTVKTGEEVGFVVDAKTAGKGKVTCVILTPDGTEAEADVIENED 1669
             D+   L  A G G+   V  GE   F V  + AG G +   +  P  ++A+ +  + +D
Sbjct: 459  RDSGSHLVKAGGSGLERGV-VGEPAEFNVWTREAGGGSLAISVEGP--SKADIEFKDRKD 289

Query: 1670 GTYDIFYTAAKPGTYVIYVRFGGVDIPNSPFTVMVS 1705
            G+ D+ Y   +PG Y + ++F    IP+SPF V +S
Sbjct: 288  GSCDVSYKVTEPGEYRVGLKFNDRHIPDSPFKVYIS 181

 Score = 67.8 bits (164), Expect = 6e-11,   Method: Compositional matrix adjust.
 Identities = 51/154 (33%), Positives = 78/154 (50%), Gaps = 2/154 (1%)
 Frame = -1

Query: 1172 SDSGAKAEVSIQNNKDGTYAVTYVPLTAGMYTLTMKYGGELVPHFPAWVKVEPAIDTSG- 1230
            S S    +  IQ  +DG Y+V +VP   G++T++++Y    +P  P    V P  D+   
Sbjct: 621  SPSNVTEDAEIQEIEDGLYSVHFVPKELGVHTVSVRYSEMHIPGSPFQFTVGPLRDSGSH 442

Query: 1231 -IKAFGPGIEGKDVFREATTDFTVDSRPLTQVGGDHIKAQITNPSGASTECFVKDNADGT 1289
             +KA G G+E   V   A  +F V +R   + GG  +   +  PS A  E   KD  DG+
Sbjct: 441  LVKAGGSGLERGVVGEPA--EFNVWTR---EAGGGSLAISVEGPSKADIE--FKDRKDGS 283

Query: 1290 YQVEYTPFEKGFHVVEVTYDDVPIPNSPFKVAVT 1323
              V Y   E G + V + ++D  IP+SPFKV ++
Sbjct: 282  CDVSYKVTEPGEYRVGLKFNDRHIPDSPFKVYIS 181

 Score = 63.5 bits (153), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 52/188 (27%), Positives = 80/188 (42%), Gaps = 3/188 (1%)
 Frame = -1

Query: 2434 LSVTIEGPSKVKMDC--QEIPEG-YKVMYTPMAPGNYLIGVKYGGPNHISRSPFKAKVTG 2490
            L+  +  PS V  D   QEI +G Y V + P   G + + V+Y    HI  SPF+     
Sbjct: 639  LAACVTSPSNVTEDAEIQEIEDGLYSVHFVPKELGVHTVSVRYS-EMHIPGSPFQ----- 478

Query: 2491 QRLVSPGSANETSSILVESVTRSSTETCYSAIPKSSSDASKVTSKGAGLSKAFVGQKSSF 2550
                                        ++  P   S +  V + G+GL +  VG+ + F
Sbjct: 477  ----------------------------FTVGPLRDSGSHLVKAGGSGLERGVVGEPAEF 382

Query: 2551 LVDCSKAGSNMLLIGVHGPTTPCEEVSMKHVGKQQYNVTYVVKERGDYVLAVKWGEEHIP 2610
             V   +AG   L I V GP+    ++  K       +V+Y V E G+Y + +K+ + HIP
Sbjct: 381  NVWTREAGGGSLAISVEGPSKA--DIEFKDRKDGSCDVSYKVTEPGEYRVGLKFNDRHIP 208

Query: 2611 GSPFHVTV 2618
             SPF V +
Sbjct: 207  DSPFKVYI 184
>29446
          Length = 1445

 Score =  202 bits (513), Expect = 2e-51,   Method: Composition-based stats.
 Identities = 97/153 (63%), Positives = 121/153 (79%), Gaps = 2/153 (1%)
 Frame = +3

Query: 4    TEKDLAEDAPWKKIQQNTFTRWCNEHLKCVNKRIGNLQTDLSDGLRLIALLEVLSQKRMH 63
            TE++LAEDA WK IQ+NTFTRW NEHL+ VNK I +L++D SDGLRL+AL+EVLS K+  
Sbjct: 960  TERELAEDAQWKIIQKNTFTRWANEHLRTVNKAIADLESDFSDGLRLVALIEVLSGKKFK 1139

Query: 64   HKYHQRPTFRQMKLENVSVALEFL-DHESIKLVSIDSKAIVDGNLKLILGLVWTLILHYS 122
            H  ++RP FR  KLENV++ L+FL D E I++V+IDS  IVD  LKLILGL+WTLILHYS
Sbjct: 1140 H-VNKRPNFRTQKLENVTLTLKFLEDDEGIRIVNIDSTDIVDKKLKLILGLIWTLILHYS 1316

Query: 123  ISMPVWEDEGDDDAK-KQTPKQRLLGWIQNKIP 154
            ISMP+WE E    ++   TPKQRLL WIQ+K+P
Sbjct: 1317 ISMPMWEGEEPTPSEGGPTPKQRLLNWIQSKVP 1415
>19277
          Length = 511

 Score =  157 bits (397), Expect(2) = 7e-44,   Method: Compositional matrix adjust.
 Identities = 76/131 (58%), Positives = 101/131 (77%), Gaps = 2/131 (1%)
 Frame = +2

Query: 2011 VVQSEIGDARRAKVYGQGLSEGRTFEMSDFIVDTRDAGYGGISLAVEGPSKVDIQTEDLE 2070
            V +SE+G+A + KV G GL+EG   E+++F+VDTR+AGYGG+SL++EGPSK DI+  D E
Sbjct: 77   VGESELGNASKVKVSGDGLTEGMANEVNEFVVDTREAGYGGMSLSIEGPSKADIECHDNE 256

Query: 2071 DGTCKVSYFPTVPGVYIVSTKFADEHVPGSPFTVKISGE--GRVRESITRTSRAPAVATV 2128
            DGTC+V+Y PT PG YI++ KFAD+HVPGSP++VKI GE   ++ E ITR   A  V  V
Sbjct: 257  DGTCRVTYKPTEPGTYIINIKFADQHVPGSPYSVKIGGEPSTKITERITRHKAAADVTHV 436

Query: 2129 GSICDLNLKIP 2139
            GS C+L+LKIP
Sbjct: 437  GSQCELSLKIP 469

 Score = 40.8 bits (94), Expect(2) = 7e-44,   Method: Composition-based stats.
 Identities = 16/25 (64%), Positives = 20/25 (80%)
 Frame = +1

Query: 1985 PREVGEHLVSIKKNGNHVANSPVSI 2009
            PRE GEHLV++ +NG H+ANSP  I
Sbjct: 1    PRETGEHLVNVYRNGKHIANSPFKI 75

 Score =  105 bits (261), Expect = 3e-22,   Method: Compositional matrix adjust.
 Identities = 49/92 (53%), Positives = 64/92 (69%)
 Frame = +2

Query: 1829 NSGSVSAYGPGLVYGVANKTATFTIVTEDAGEGGLDLAIEGPSKAEISCIDNKDGTCTVT 1888
            N+  V   G GL  G+AN+   F + T +AG GG+ L+IEGPSKA+I C DN+DGTC VT
Sbjct: 98   NASKVKVSGDGLTEGMANEVNEFVVDTREAGYGGMSLSIEGPSKADIECHDNEDGTCRVT 277

Query: 1889 YLPTLPGDYSILVKYNDKHIPGSPFTAKITGR 1920
            Y PT PG Y I +K+ D+H+PGSP++ KI G 
Sbjct: 278  YKPTEPGTYIINIKFADQHVPGSPYSVKIGGE 373

 Score = 94.4 bits (233), Expect(2) = 9e-22,   Method: Compositional matrix adjust.
 Identities = 47/97 (48%), Positives = 65/97 (67%)
 Frame = +2

Query: 2201 TVGPLGEGGAHKVRAGGPGLERGEAGIPAEFSIWTREAGAGGLSIAVEGPSKAEITFDDH 2260
            +VG    G A KV+  G GL  G A    EF + TREAG GG+S+++EGPSKA+I   D+
Sbjct: 74   SVGESELGNASKVKVSGDGLTEGMANEVNEFVVDTREAGYGGMSLSIEGPSKADIECHDN 253

Query: 2261 KNGSCGVSYIAQEPGNYEVSIKFNDEHIPDSPYLVPV 2297
            ++G+C V+Y   EPG Y ++IKF D+H+P SPY V +
Sbjct: 254  EDGTCRVTYKPTEPGTYIINIKFADQHVPGSPYSVKI 364

 Score = 30.0 bits (66), Expect(2) = 9e-22,   Method: Composition-based stats.
 Identities = 12/28 (42%), Positives = 17/28 (60%)
 Frame = +1

Query: 2176 PQEMGVHTVSVKYRGQHVTGSPFQFTVG 2203
            P+E G H V+V   G+H+  SPF+   G
Sbjct: 1    PRETGEHLVNVYRNGKHIANSPFKICRG 84

 Score = 91.3 bits (225), Expect = 5e-18,   Method: Compositional matrix adjust.
 Identities = 44/101 (43%), Positives = 61/101 (60%), Gaps = 1/101 (0%)
 Frame = +2

Query: 1314 PNSPFK-VAVTEGCQPSRVHAQGPGLKEAFTNKSNVFTVVTRGAGIGGLGITVEGPSESK 1372
            P +P + V  +E    S+V   G GL E   N+ N F V TR AG GG+ +++EGPS++ 
Sbjct: 56   PTAPSRSVGESELGNASKVKVSGDGLTEGMANEVNEFVVDTREAGYGGMSLSIEGPSKAD 235

Query: 1373 INCRDNKDGSCSAEYIPFAPGDYDVNITYGGVHIPGSPFRV 1413
            I C DN+DG+C   Y P  PG Y +NI +   H+PGSP+ V
Sbjct: 236  IECHDNEDGTCRVTYKPTEPGTYIINIKFADQHVPGSPYSV 358

 Score = 88.2 bits (217), Expect(2) = 1e-17,   Method: Compositional matrix adjust.
 Identities = 40/89 (44%), Positives = 54/89 (60%)
 Frame = +2

Query: 1039 DPTKVKAHGPGLEGGLVGKPAEFTIDTKXXXXXXXXXXVEGPCEAKIECSDNGDGTCSVS 1098
            + +KVK  G GL  G+  +  EF +DT+          +EGP +A IEC DN DGTC V+
Sbjct: 98   NASKVKVSGDGLTEGMANEVNEFVVDTREAGYGGMSLSIEGPSKADIECHDNEDGTCRVT 277

Query: 1099 YLPTKPGEYFVNILFEEVHIPGSPFKADI 1127
            Y PT+PG Y +NI F + H+PGSP+   I
Sbjct: 278  YKPTEPGTYIINIKFADQHVPGSPYSVKI 364

 Score = 21.9 bits (45), Expect(2) = 1e-17,   Method: Composition-based stats.
 Identities = 9/25 (36%), Positives = 14/25 (56%)
 Frame = +1

Query: 1008 PREEGLFAVDVTYDGHPVPGSPYTV 1032
            PRE G   V+V  +G  +  SP+ +
Sbjct: 1    PRETGEHLVNVYRNGKHIANSPFKI 75

 Score = 69.7 bits (169), Expect(2) = 1e-15,   Method: Compositional matrix adjust.
 Identities = 43/122 (35%), Positives = 66/122 (54%), Gaps = 1/122 (0%)
 Frame = +2

Query: 2392 VGEPGQAGNPALVSAYGAGLETGTTGIQSEFFINTTQAGPGTLSVTIEGPSKVKMDCQEI 2451
            VGE  + GN + V   G GL  G     +EF ++T +AG G +S++IEGPSK  ++C + 
Sbjct: 77   VGE-SELGNASKVKVSGDGLTEGMANEVNEFVVDTREAGYGGMSLSIEGPSKADIECHDN 253

Query: 2452 PEGY-KVMYTPMAPGNYLIGVKYGGPNHISRSPFKAKVTGQRLVSPGSANETSSILVESV 2510
             +G  +V Y P  PG Y+I +K+    H+  SP+  K+ G          E S+ + E +
Sbjct: 254  EDGTCRVTYKPTEPGTYIINIKF-ADQHVPGSPYSVKIGG----------EPSTKITERI 400

Query: 2511 TR 2512
            TR
Sbjct: 401  TR 406

 Score = 33.9 bits (76), Expect(2) = 1e-15,   Method: Composition-based stats.
 Identities = 14/29 (48%), Positives = 18/29 (62%)
 Frame = +1

Query: 2366 PHENGIHTIDVKFNGSHVVGSPFKVRVGE 2394
            P E G H ++V  NG H+  SPFK+  GE
Sbjct: 1    PRETGEHLVNVYRNGKHIANSPFKICRGE 87

 Score = 68.9 bits (167), Expect(2) = 2e-12,   Method: Compositional matrix adjust.
 Identities = 35/86 (40%), Positives = 49/86 (56%)
 Frame = +2

Query: 551 KVRAWGPGLHGGIVGRSADFVVESIGSEVGTLGFAIEGPSQAKIEYDDQNDGSCDVKYWP 610
           KV+  G GL  G+     +FVV++  +  G +  +IEGPS+A IE  D  DG+C V Y P
Sbjct: 107 KVKVSGDGLTEGMANEVNEFVVDTREAGYGGMSLSIEGPSKADIECHDNEDGTCRVTYKP 286

Query: 611 KEPGEYAVHIMCDDEDIKDSPYMAFI 636
            EPG Y ++I   D+ +  SPY   I
Sbjct: 287 TEPGTYIINIKFADQHVPGSPYSVKI 364

 Score = 23.5 bits (49), Expect(2) = 2e-12,   Method: Composition-based stats.
 Identities = 11/28 (39%), Positives = 15/28 (53%)
 Frame = +1

Query: 517 PSTPGKYSVAVTWGGHHIPKSPFEVQVG 544
           P   G++ V V   G HI  SPF++  G
Sbjct: 1   PRETGEHLVNVYRNGKHIANSPFKICRG 84

 Score = 66.2 bits (160), Expect(2) = 5e-12,   Method: Compositional matrix adjust.
 Identities = 38/106 (35%), Positives = 64/106 (60%), Gaps = 1/106 (0%)
 Frame = +2

Query: 1407 PGSPFR-VPSKDVVDPSKVKIAGPGLSSCVRACIPQSFTVDSSKAGLAPLEVRVLGPRGL 1465
            P +P R V   ++ + SKVK++G GL+  +   + + F VD+ +AG   + + + GP   
Sbjct: 56   PTAPSRSVGESELGNASKVKVSGDGLTEGMANEVNE-FVVDTREAGYGGMSLSIEGPSKA 232

Query: 1466 VEPVNVVDNGDGTHTVTYTPSQEGPYIVSVKYADEEIPRSPFKVKV 1511
               +   DN DGT  VTY P++ G YI+++K+AD+ +P SP+ VK+
Sbjct: 233  --DIECHDNEDGTCRVTYKPTEPGTYIINIKFADQHVPGSPYSVKI 364

 Score = 25.0 bits (53), Expect(2) = 5e-12,   Method: Composition-based stats.
 Identities = 10/25 (40%), Positives = 15/25 (60%)
 Frame = +1

Query: 1389 PFAPGDYDVNITYGGVHIPGSPFRV 1413
            P   G++ VN+   G HI  SPF++
Sbjct: 1    PRETGEHLVNVYRNGKHIANSPFKI 75

 Score = 62.4 bits (150), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 43/122 (35%), Positives = 69/122 (56%), Gaps = 2/122 (1%)
 Frame = +2

Query: 1600 PLSPYR-IRATQTGDASKCLATGPGIAPTVKTGEEVG-FVVDAKTAGKGKVTCVILTPDG 1657
            P +P R +  ++ G+ASK   +G G+  T     EV  FVVD + AG G ++  I  P  
Sbjct: 56   PTAPSRSVGESELGNASKVKVSGDGL--TEGMANEVNEFVVDTREAGYGGMSLSIEGP-- 223

Query: 1658 TEAEADVIENEDGTYDIFYTAAKPGTYVIYVRFGGVDIPNSPFTVMVSRVPSPEPALTSR 1717
            ++A+ +  +NEDGT  + Y   +PGTY+I ++F    +P SP++V +   PS +  +T R
Sbjct: 224  SKADIECHDNEDGTCRVTYKPTEPGTYIINIKFADQHVPGSPYSVKIGGEPSTK--ITER 397

Query: 1718 ST 1719
             T
Sbjct: 398  IT 403

 Score = 55.8 bits (133), Expect(2) = 3e-09,   Method: Compositional matrix adjust.
 Identities = 34/91 (37%), Positives = 47/91 (51%)
 Frame = +2

Query: 1132 DPSKVVASGPGLEHGKVGEPGILCVDCSEAGPGTLGLEAVSDSGAKAEVSIQNNKDGTYA 1191
            + SKV  SG GL  G   E     VD  EAG G + L    +  +KA++   +N+DGT  
Sbjct: 98   NASKVKVSGDGLTEGMANEVNEFVVDTREAGYGGMSLSI--EGPSKADIECHDNEDGTCR 271

Query: 1192 VTYVPLTAGMYTLTMKYGGELVPHFPAWVKV 1222
            VTY P   G Y + +K+  + VP  P  VK+
Sbjct: 272  VTYKPTEPGTYIINIKFADQHVPGSPYSVKI 364

 Score = 26.2 bits (56), Expect(2) = 3e-09,   Method: Composition-based stats.
 Identities = 11/24 (45%), Positives = 14/24 (58%)
 Frame = +1

Query: 1101 PTKPGEYFVNILFEEVHIPGSPFK 1124
            P + GE+ VN+     HI  SPFK
Sbjct: 1    PRETGEHLVNVYRNGKHIANSPFK 72

 Score = 60.8 bits (146), Expect = 6e-09,   Method: Compositional matrix adjust.
 Identities = 39/94 (41%), Positives = 59/94 (62%), Gaps = 2/94 (2%)
 Frame = +2

Query: 1516 DASKVTASGPGLSAYGVPASLPVEFAIDARDAGEGLLAVQITDQEGKPQRATV--HDNKD 1573
            +ASKV  SG GL+  G+ A+   EF +D R+AG G +++ I   EG P +A +  HDN+D
Sbjct: 98   NASKVKVSGDGLTE-GM-ANEVNEFVVDTREAGYGGMSLSI---EG-PSKADIECHDNED 259

Query: 1574 GTYAVTYIPDKTGRYMIGVTYGGDNIPLSPYRIR 1607
            GT  VTY P + G Y+I + +   ++P SPY ++
Sbjct: 260  GTCRVTYKPTEPGTYIINIKFADQHVPGSPYSVK 361

 Score = 58.9 bits (141), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 33/96 (34%), Positives = 52/96 (54%)
 Frame = +2

Query: 352 GDASKVTAKGPGLETTGNIANKPTYFDIYTAGAGVGDIGIEVEDPQGKNSVELLVEDRGN 411
           G+ASKV   G GL  T  +AN+   F + T  AG G + + +E P   +  ++   D  +
Sbjct: 95  GNASKVKVSGDGL--TEGMANEVNEFVVDTREAGYGGMSLSIEGP---SKADIECHDNED 259

Query: 412 QVYRCVYKPVQPGPHVVKVSFAGDAIPKSPFGVQIG 447
              R  YKP +PG +++ + FA   +P SP+ V+IG
Sbjct: 260 GTCRVTYKPTEPGTYIINIKFADQHVPGSPYSVKIG 367

 Score = 58.2 bits (139), Expect = 4e-08,   Method: Compositional matrix adjust.
 Identities = 40/113 (35%), Positives = 55/113 (48%), Gaps = 1/113 (0%)
 Frame = +2

Query: 728 PHSPYR-VNIGQGSHPQKVKVFGPGVERSGLKANEPTHFTVDCTEAGEGDVSVGIKCDAR 786
           P +P R V   +  +  KVKV G G+      ANE   F VD  EAG G +S+ I+  ++
Sbjct: 56  PTAPSRSVGESELGNASKVKVSGDGLTEG--MANEVNEFVVDTREAGYGGMSLSIEGPSK 229

Query: 787 VLSDDEEDVDFDIIHNANDTFTVKYVPPAPGRYTIKVLFASQEIPASPFRVKV 839
                    D +   N + T  V Y P  PG Y I + FA Q +P SP+ VK+
Sbjct: 230 --------ADIECHDNEDGTCRVTYKPTEPGTYIINIKFADQHVPGSPYSVKI 364

 Score = 53.1 bits (126), Expect(2) = 6e-08,   Method: Compositional matrix adjust.
 Identities = 31/99 (31%), Positives = 53/99 (53%)
 Frame = +2

Query: 448 EACNPNACRASGRGLQPKGVRIRETADFKVDTKAAGSGELGVTVKGPKGLEELVKQKGFL 507
           E  N +  + SG GL  +G+   E  +F VDT+ AG G + ++++GP   +  ++     
Sbjct: 89  ELGNASKVKVSGDGLT-EGMA-NEVNEFVVDTREAGYGGMSLSIEGPSKAD--IECHDNE 256

Query: 508 DGVYSFEYYPSTPGKYSVAVTWGGHHIPKSPFEVQVGPE 546
           DG     Y P+ PG Y + + +   H+P SP+ V++G E
Sbjct: 257 DGTCRVTYKPTEPGTYIINIKFADQHVPGSPYSVKIGGE 373

 Score = 24.3 bits (51), Expect(2) = 6e-08,   Method: Composition-based stats.
 Identities = 12/29 (41%), Positives = 15/29 (51%)
 Frame = +1

Query: 420 PVQPGPHVVKVSFAGDAIPKSPFGVQIGE 448
           P + G H+V V   G  I  SPF +  GE
Sbjct: 1   PRETGEHLVNVYRNGKHIANSPFKICRGE 87

 Score = 54.3 bits (129), Expect = 6e-07,   Method: Compositional matrix adjust.
 Identities = 29/91 (31%), Positives = 50/91 (54%)
 Frame = +2

Query: 2528 DASKVTSKGAGLSKAFVGQKSSFLVDCSKAGSNMLLIGVHGPTTPCEEVSMKHVGKQQYN 2587
            +ASKV   G GL++    + + F+VD  +AG   + + + GP+    E      G  +  
Sbjct: 98   NASKVKVSGDGLTEGMANEVNEFVVDTREAGYGGMSLSIEGPSKADIECHDNEDGTCR-- 271

Query: 2588 VTYVVKERGDYVLAVKWGEEHIPGSPFHVTV 2618
            VTY   E G Y++ +K+ ++H+PGSP+ V +
Sbjct: 272  VTYKPTEPGTYIINIKFADQHVPGSPYSVKI 364

 Score = 50.1 bits (118), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 33/103 (32%), Positives = 51/103 (49%)
 Frame = +2

Query: 1227 DTSGIKAFGPGIEGKDVFREATTDFTVDSRPLTQVGGDHIKAQITNPSGASTECFVKDNA 1286
            + S +K  G G+   +       +F VD+R   + G   +   I  PS A  EC   DN 
Sbjct: 98   NASKVKVSGDGL--TEGMANEVNEFVVDTR---EAGYGGMSLSIEGPSKADIECH--DNE 256

Query: 1287 DGTYQVEYTPFEKGFHVVEVTYDDVPIPNSPFKVAVTEGCQPS 1329
            DGT +V Y P E G +++ + + D  +P SP+ V +  G +PS
Sbjct: 257  DGTCRVTYKPTEPGTYIINIKFADQHVPGSPYSVKI--GGEPS 379

 Score = 40.8 bits (94), Expect(2) = 8e-04,   Method: Compositional matrix adjust.
 Identities = 29/94 (30%), Positives = 46/94 (48%)
 Frame = +2

Query: 644 NPDLVQAYGPGLEKSGCTINNPAEFIVDPKDAGSAPLKILAQDGEGQPIDIQMKSRMDGT 703
           N   V+  G GL +     N   EF+VD ++AG   +  L+ +G  +  DI+     DGT
Sbjct: 98  NASKVKVSGDGLTEG--MANEVNEFVVDTREAGYGGMS-LSIEGPSKA-DIECHDNEDGT 265

Query: 704 YACSYTPLKAIKHTIAVVWGGVNIPHSPYRVNIG 737
              +Y P +   + I + +   ++P SPY V IG
Sbjct: 266 CRVTYKPTEPGTYIINIKFADQHVPGSPYSVKIG 367

 Score = 22.3 bits (46), Expect(2) = 8e-04,   Method: Composition-based stats.
 Identities = 8/23 (34%), Positives = 16/23 (69%)
 Frame = +1

Query: 610 PKEPGEYAVHIMCDDEDIKDSPY 632
           P+E GE+ V++  + + I +SP+
Sbjct: 1   PRETGEHLVNVYRNGKHIANSPF 69

 Score = 43.9 bits (102), Expect = 8e-04,   Method: Compositional matrix adjust.
 Identities = 29/95 (30%), Positives = 50/95 (52%)
 Frame = +2

Query: 844 DASKVKAEGPGLSKAGVENGKPTHFTVHTKGAGKAPLNVQFSSPLPGEAVKDLDIIDNYD 903
           +ASKVK  G GL++ G+ N +   F V T+ AG   +++    P    +  D++  DN D
Sbjct: 98  NASKVKVSGDGLTE-GMAN-EVNEFVVDTREAGYGGMSLSIEGP----SKADIECHDNED 259

Query: 904 YSHTVKYTPTQQGNMQVLVTYGGDPIPKSPFTVGV 938
            +  V Y PT+ G   + + +    +P SP++V +
Sbjct: 260 GTCRVTYKPTEPGTYIINIKFADQHVPGSPYSVKI 364

 Score = 40.8 bits (94), Expect(2) = 0.001,   Method: Compositional matrix adjust.
 Identities = 30/104 (28%), Positives = 46/104 (44%)
 Frame = +2

Query: 2334 GKIDAKVHSPSGAVEECHVSELEPDKYAVRFIPHENGIHTIDVKFNGSHVVGSPFKVRVG 2393
            G +   +  PS A  ECH  + E     V + P E G + I++KF   HV GSP+ V++G
Sbjct: 194  GGMSLSIEGPSKADIECH--DNEDGTCRVTYKPTEPGTYIINIKFADQHVPGSPYSVKIG 367

Query: 2394 EPGQAGNPALVSAYGAGLETGTTGIQSEFFINTTQAGPGTLSVT 2437
                      ++ + A  +    G Q E  +      PGT  +T
Sbjct: 368  GEPSTKITERITRHKAAADVTHVGSQCELSLKI----PGTSPLT 487

 Score = 21.6 bits (44), Expect(2) = 0.001,   Method: Composition-based stats.
 Identities = 8/24 (33%), Positives = 16/24 (66%)
 Frame = +1

Query: 2272 QEPGNYEVSIKFNDEHIPDSPYLV 2295
            +E G + V++  N +HI +SP+ +
Sbjct: 4    RETGEHLVNVYRNGKHIANSPFKI 75

 Score = 43.1 bits (100), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 20/46 (43%), Positives = 28/46 (60%)
 Frame = +2

Query: 1780 KATPEIVDNKDGTVTVRYAPTEVGLHEMHIKYRGSHIPGNPLQFYV 1825
            KA  E  DN+DGT  V Y PTE G + ++IK+   H+PG+P    +
Sbjct: 227  KADIECHDNEDGTCRVTYKPTEPGTYIINIKFADQHVPGSPYSVKI 364

 Score = 40.0 bits (92), Expect = 0.013,   Method: Compositional matrix adjust.
 Identities = 24/81 (29%), Positives = 40/81 (49%)
 Frame = +2

Query: 267 TGNMVKQPAKFTVDTISAGQGDVMVFVEDPEGNKEEARVTPDSDKNKTYSVEYLPKVTGL 326
           T  M  +  +F VDT  AG G + + +E P     +A +    +++ T  V Y P   G 
Sbjct: 134 TEGMANEVNEFVVDTREAGYGGMSLSIEGPS----KADIECHDNEDGTCRVTYKPTEPGT 301

Query: 327 HKVIVLFAGQHISKSPFEVNV 347
           + + + FA QH+  SP+ V +
Sbjct: 302 YIINIKFADQHVPGSPYSVKI 364

 Score = 38.9 bits (89), Expect = 0.026,   Method: Compositional matrix adjust.
 Identities = 36/140 (25%), Positives = 63/140 (45%), Gaps = 11/140 (7%)
 Frame = +2

Query: 935  TVGVAAPLDLSKIKING------LENRVEVGKDQEFAIDTNGAGGQGKLDVTILSPSRKV 988
            +VG +   + SK+K++G      + N V      EF +DT  AG  G + ++I  PS+  
Sbjct: 74   SVGESELGNASKVKVSGDGLTEGMANEV-----NEFVVDTREAG-YGGMSLSIEGPSKAD 235

Query: 989  VPCLVAPVAGRECSTAK--FIPREEGLFAVDVTYDGHPVPGSPYTVEASLPPDPT---KV 1043
            + C        E  T +  + P E G + +++ +    VPGSPY+V+    P      ++
Sbjct: 236  IEC-----HDNEDGTCRVTYKPTEPGTYIINIKFADQHVPGSPYSVKIGGEPSTKITERI 400

Query: 1044 KAHGPGLEGGLVGKPAEFTI 1063
              H    +   VG   E ++
Sbjct: 401  TRHKAAADVTHVGSQCELSL 460

 Score = 32.3 bits (72), Expect = 2.6,   Method: Compositional matrix adjust.
 Identities = 12/32 (37%), Positives = 20/32 (62%)
 Frame = +2

Query: 2172 VRFVPQEMGVHTVSVKYRGQHVTGSPFQFTVG 2203
            V + P E G + +++K+  QHV GSP+   +G
Sbjct: 272  VTYKPTEPGTYIINIKFADQHVPGSPYSVKIG 367
>21436
          Length = 546

 Score =  149 bits (376), Expect = 1e-35,   Method: Compositional matrix adjust.
 Identities = 75/152 (49%), Positives = 105/152 (69%)
 Frame = -1

Query: 701 DGTYACSYTPLKAIKHTIAVVWGGVNIPHSPYRVNIGQGSHPQKVKVFGPGVERSGLKAN 760
           DGTYAC Y PL+ +KHT++V +GGV +P+SP+RV++ + S P KVK+ GPGV  +G+K  
Sbjct: 540 DGTYACRYMPLRPVKHTVSVNFGGVAVPNSPFRVHVAEPSDPSKVKISGPGVT-NGIKTM 364

Query: 761 EPTHFTVDCTEAGEGDVSVGIKCDARVLSDDEEDVDFDIIHNANDTFTVKYVPPAPGRYT 820
            PT+FTVDC +AG GDV+VG+  D R +     DV      N + TFTV+Y P  PG YT
Sbjct: 363 SPTYFTVDCKQAGPGDVAVGL-TDGRGM-----DVPVKTTGNQDGTFTVEYEPKLPGTYT 202

Query: 821 IKVLFASQEIPASPFRVKVDPSHDASKVKAEG 852
           + V FA  E+P+SP +VKV+P+ D S ++ +G
Sbjct: 201 VMVYFADVEVPSSPVKVKVEPNIDVSSIRVDG 106

 Score =  124 bits (310), Expect = 7e-28,   Method: Compositional matrix adjust.
 Identities = 69/167 (41%), Positives = 94/167 (56%)
 Frame = -1

Query: 1378 NKDGSCSAEYIPFAPGDYDVNITYGGVHIPGSPFRVPSKDVVDPSKVKIAGPGLSSCVRA 1437
            N+DG+ +  Y+P  P  + V++ +GGV +P SPFRV   +  DPSKVKI+GPG+++ ++ 
Sbjct: 546  NRDGTYACRYMPLRPVKHTVSVNFGGVAVPNSPFRVHVAEPSDPSKVKISGPGVTNGIKT 367

Query: 1438 CIPQSFTVDSSKAGLAPLEVRVLGPRGLVEPVNVVDNGDGTHTVTYTPSQEGPYIVSVKY 1497
              P  FTVD  +AG   + V +   RG+  PV    N DGT TV Y P   G Y V V +
Sbjct: 366  MSPTYFTVDCKQAGPGDVAVGLTDGRGMDVPVKTTGNQDGTFTVEYEPKLPGTYTVMVYF 187

Query: 1498 ADEEIPRSPFKVKVLPTYDASKVTASGPGLSAYGVPASLPVEFAIDA 1544
            AD E+P SP KVKV P  D S +   G     +      P EF +DA
Sbjct: 186  ADVEVPSSPVKVKVEPNIDVSSIRVDGLDSRVF---IEAPSEFVVDA 55

 Score =  120 bits (301), Expect = 7e-27,   Method: Compositional matrix adjust.
 Identities = 72/187 (38%), Positives = 101/187 (54%), Gaps = 3/187 (1%)
 Frame = -1

Query: 1090 NGDGTCSVSYLPTKPGEYFVNILFEEVHIPGSPFKADIEMPFDPSKVVASGPGLEHG-KV 1148
            N DGT +  Y+P +P ++ V++ F  V +P SPF+  +  P DPSKV  SGPG+ +G K 
Sbjct: 546  NRDGTYACRYMPLRPVKHTVSVNFGGVAVPNSPFRVHVAEPSDPSKVKISGPGVTNGIKT 367

Query: 1149 GEPGILCVDCSEAGPGTLGLEAVSDSGAKAEVSIQNNKDGTYAVTYVPLTAGMYTLTMKY 1208
              P    VDC +AGPG + +      G    V    N+DGT+ V Y P   G YT+ + +
Sbjct: 366  MSPTYFTVDCKQAGPGDVAVGLTDGRGMDVPVKTTGNQDGTFTVEYEPKLPGTYTVMVYF 187

Query: 1209 GGELVPHFPAWVKVEPAIDTSGIKAFGPGIEGKD--VFREATTDFTVDSRPLTQVGGDHI 1266
                VP  P  VKVEP ID S I+     ++G D  VF EA ++F VD+  L   G   +
Sbjct: 186  ADVEVPSSPVKVKVEPNIDVSSIR-----VDGLDSRVFIEAPSEFVVDASVLDPKGQGEV 22

Query: 1267 KAQITNP 1273
            +A +T P
Sbjct: 21   EAILTTP 1

 Score =  101 bits (251), Expect = 4e-21,   Method: Compositional matrix adjust.
 Identities = 52/143 (36%), Positives = 78/143 (54%)
 Frame = -1

Query: 414 YRCVYKPVQPGPHVVKVSFAGDAIPKSPFGVQIGEACNPNACRASGRGLQPKGVRIRETA 473
           Y C Y P++P  H V V+F G A+P SPF V + E  +P+  + SG G+   G++     
Sbjct: 531 YACRYMPLRPVKHTVSVNFGGVAVPNSPFRVHVAEPSDPSKVKISGPGVT-NGIKTMSPT 355

Query: 474 DFKVDTKAAGSGELGVTVKGPKGLEELVKQKGFLDGVYSFEYYPSTPGKYSVAVTWGGHH 533
            F VD K AG G++ V +   +G++  VK  G  DG ++ EY P  PG Y+V V +    
Sbjct: 354 YFTVDCKQAGPGDVAVGLTDGRGMDVPVKTTGNQDGTFTVEYEPKLPGTYTVMVYFADVE 175

Query: 534 IPKSPFEVQVGPEAGMQKVRAWG 556
           +P SP +V+V P   +  +R  G
Sbjct: 174 VPSSPVKVKVEPNIDVSSIRVDG 106

 Score = 99.0 bits (245), Expect = 2e-20,   Method: Compositional matrix adjust.
 Identities = 62/186 (33%), Positives = 99/186 (53%), Gaps = 3/186 (1%)
 Frame = -1

Query: 802 NANDTFTVKYVPPAPGRYTIKVLFASQEIPASPFRVKVDPSHDASKVKAEGPGLSKAGVE 861
           N + T+  +Y+P  P ++T+ V F    +P SPFRV V    D SKVK  GPG++  G++
Sbjct: 546 NRDGTYACRYMPLRPVKHTVSVNFGGVAVPNSPFRVHVAEPSDPSKVKISGPGVTN-GIK 370

Query: 862 NGKPTHFTVHTKGAGKAPLNVQFSSPLPGEAVK-DLDIIDNYDYSHTVKYTPTQQGNMQV 920
              PT+FTV  K AG   + V  +    G  +   +    N D + TV+Y P   G   V
Sbjct: 369 TMSPTYFTVDCKQAGPGDVAVGLTD---GRGMDVPVKTTGNQDGTFTVEYEPKLPGTYTV 199

Query: 921 LVTYGGDPIPKSPFTVGVAAPLDLSKIKINGLENRVEVGKDQEFAIDTN--GAGGQGKLD 978
           +V +    +P SP  V V   +D+S I+++GL++RV +    EF +D +     GQG+++
Sbjct: 198 MVYFADVEVPSSPVKVKVEPNIDVSSIRVDGLDSRVFIEAPSEFVVDASVLDPKGQGEVE 19

Query: 979 VTILSP 984
             + +P
Sbjct: 18  AILTTP 1

 Score = 95.1 bits (235), Expect = 3e-19,   Method: Compositional matrix adjust.
 Identities = 49/134 (36%), Positives = 72/134 (53%)
 Frame = -1

Query: 1571 NKDGTYAVTYIPDKTGRYMIGVTYGGDNIPLSPYRIRATQTGDASKCLATGPGIAPTVKT 1630
            N+DGTYA  Y+P +  ++ + V +GG  +P SP+R+   +  D SK   +GPG+   +KT
Sbjct: 546  NRDGTYACRYMPLRPVKHTVSVNFGGVAVPNSPFRVHVAEPSDPSKVKISGPGVTNGIKT 367

Query: 1631 GEEVGFVVDAKTAGKGKVTCVILTPDGTEAEADVIENEDGTYDIFYTAAKPGTYVIYVRF 1690
                 F VD K AG G V   +    G +       N+DGT+ + Y    PGTY + V F
Sbjct: 366  MSPTYFTVDCKQAGPGDVAVGLTDGRGMDVPVKTTGNQDGTFTVEYEPKLPGTYTVMVYF 187

Query: 1691 GGVDIPNSPFTVMV 1704
              V++P+SP  V V
Sbjct: 186  ADVEVPSSPVKVKV 145

 Score = 92.8 bits (229), Expect = 2e-18,   Method: Compositional matrix adjust.
 Identities = 64/183 (34%), Positives = 88/183 (48%), Gaps = 3/183 (1%)
 Frame = -1

Query: 1285 NADGTYQVEYTPFEKGFHVVEVTYDDVPIPNSPFKVAVTEGCQPSRVHAQGPGLKEAFTN 1344
            N DGTY   Y P     H V V +  V +PNSPF+V V E   PS+V   GPG+      
Sbjct: 546  NRDGTYACRYMPLRPVKHTVSVNFGGVAVPNSPFRVHVAEPSDPSKVKISGPGVTNGIKT 367

Query: 1345 KS-NVFTVVTRGAGIG--GLGITVEGPSESKINCRDNKDGSCSAEYIPFAPGDYDVNITY 1401
             S   FTV  + AG G   +G+T     +  +    N+DG+ + EY P  PG Y V + +
Sbjct: 366  MSPTYFTVDCKQAGPGDVAVGLTDGRGMDVPVKTTGNQDGTFTVEYEPKLPGTYTVMVYF 187

Query: 1402 GGVHIPGSPFRVPSKDVVDPSKVKIAGPGLSSCVRACIPQSFTVDSSKAGLAPLEVRVLG 1461
              V +P SP +V  +  +D S +++   GL S V    P  F VD+S          VL 
Sbjct: 186  ADVEVPSSPVKVKVEPNIDVSSIRVD--GLDSRVFIEAPSEFVVDAS----------VLD 43

Query: 1462 PRG 1464
            P+G
Sbjct: 42   PKG 34

 Score = 91.3 bits (225), Expect = 5e-18,   Method: Compositional matrix adjust.
 Identities = 62/185 (33%), Positives = 89/185 (48%), Gaps = 3/185 (1%)
 Frame = -1

Query: 1474 NGDGTHTVTYTPSQEGPYIVSVKYADEEIPRSPFKVKVLPTYDASKVTASGPGLSAYGVP 1533
            N DGT+   Y P +   + VSV +    +P SPF+V V    D SKV  SGPG++  G+ 
Sbjct: 546  NRDGTYACRYMPLRPVKHTVSVNFGGVAVPNSPFRVHVAEPSDPSKVKISGPGVTN-GIK 370

Query: 1534 ASLPVEFAIDARDAGEGLLAVQITDQEGKPQRATVHDNKDGTYAVTYIPDKTGRYMIGVT 1593
               P  F +D + AG G +AV +TD  G         N+DGT+ V Y P   G Y + V 
Sbjct: 369  TMSPTYFTVDCKQAGPGDVAVGLTDGRGMDVPVKTTGNQDGTFTVEYEPKLPGTYTVMVY 190

Query: 1594 YGGDNIPLSPYRIRATQTGDASKCLATGPGIAPTVKTGEEVGFVVDAKT---AGKGKVTC 1650
            +    +P SP +++     D S     G      ++   E  FVVDA      G+G+V  
Sbjct: 189  FADVEVPSSPVKVKVEPNIDVSSIRVDGLDSRVFIEAPSE--FVVDASVLDPKGQGEVEA 16

Query: 1651 VILTP 1655
            ++ TP
Sbjct: 15   ILTTP 1

 Score = 80.5 bits (197), Expect = 7e-15,   Method: Compositional matrix adjust.
 Identities = 53/151 (35%), Positives = 75/151 (49%)
 Frame = -1

Query: 1185 NKDGTYAVTYVPLTAGMYTLTMKYGGELVPHFPAWVKVEPAIDTSGIKAFGPGIEGKDVF 1244
            N+DGTYA  Y+PL    +T+++ +GG  VP+ P  V V    D S +K  GPG+    + 
Sbjct: 546  NRDGTYACRYMPLRPVKHTVSVNFGGVAVPNSPFRVHVAEPSDPSKVKISGPGVT-NGIK 370

Query: 1245 REATTDFTVDSRPLTQVGGDHIKAQITNPSGASTECFVKDNADGTYQVEYTPFEKGFHVV 1304
              + T FTVD +   Q G   +   +T+  G         N DGT+ VEY P   G + V
Sbjct: 369  TMSPTYFTVDCK---QAGPGDVAVGLTDGRGMDVPVKTTGNQDGTFTVEYEPKLPGTYTV 199

Query: 1305 EVTYDDVPIPNSPFKVAVTEGCQPSRVHAQG 1335
             V + DV +P+SP KV V      S +   G
Sbjct: 198  MVYFADVEVPSSPVKVKVEPNIDVSSIRVDG 106

 Score = 77.0 bits (188), Expect = 8e-14,   Method: Compositional matrix adjust.
 Identities = 49/168 (29%), Positives = 84/168 (50%), Gaps = 4/168 (2%)
 Frame = -1

Query: 1788 NKDGTVTVRYAPTEVGLHEMHIKYRGSHIPGNPLQFYVNYPNSGS-VSAYGPGLVYGVAN 1846
            N+DGT   RY P     H + + + G  +P +P + +V  P+  S V   GPG+  G+  
Sbjct: 546  NRDGTYACRYMPLRPVKHTVSVNFGGVAVPNSPFRVHVAEPSDPSKVKISGPGVTNGIKT 367

Query: 1847 KTAT-FTIVTEDAGEGGLDLAIEGPSKAEI--SCIDNKDGTCTVTYLPTLPGDYSILVKY 1903
             + T FT+  + AG G + + +      ++      N+DGT TV Y P LPG Y+++V +
Sbjct: 366  MSPTYFTVDCKQAGPGDVAVGLTDGRGMDVPVKTTGNQDGTFTVEYEPKLPGTYTVMVYF 187

Query: 1904 NDKHIPGSPFTAKITGRLCCFFSDDNRRCSQVKLGSAADFLLDISETD 1951
             D  +P SP   K+   +       +   S+V + + ++F++D S  D
Sbjct: 186  ADVEVPSSPVKVKVEPNIDVSSIRVDGLDSRVFIEAPSEFVVDASVLD 43

 Score = 75.1 bits (183), Expect = 3e-13,   Method: Compositional matrix adjust.
 Identities = 60/190 (31%), Positives = 92/190 (48%), Gaps = 5/190 (2%)
 Frame = -1

Query: 310 DKNKTYSVEYLPKVTGLHKVIVLFAGQHISKSPFEVNVDKAQGDASKVTAKGPGLETTGN 369
           +++ TY+  Y+P     H V V F G  +  SPF V+V +   D SKV   GPG+ T G 
Sbjct: 546 NRDGTYACRYMPLRPVKHTVSVNFGGVAVPNSPFRVHVAEPS-DPSKVKISGPGV-TNGI 373

Query: 370 IANKPTYFDIYTAGAGVGDIGIEVEDPQGKNSVELLVEDRGNQ--VYRCVYKPVQPGPHV 427
               PTYF +    AG GD+ + + D +G   +++ V+  GNQ   +   Y+P  PG + 
Sbjct: 372 KTMSPTYFTVDCKQAGPGDVAVGLTDGRG---MDVPVKTTGNQDGTFTVEYEPKLPGTYT 202

Query: 428 VKVSFAGDAIPKSPFGVQIGEACNPNACRASGRGLQPKGVRIRETADFKVDTKA---AGS 484
           V V FA   +P SP  V++    + ++ R  G   +   V I   ++F VD       G 
Sbjct: 201 VMVYFADVEVPSSPVKVKVEPNIDVSSIRVDGLDSR---VFIEAPSEFVVDASVLDPKGQ 31

Query: 485 GELGVTVKGP 494
           GE+   +  P
Sbjct: 30  GEVEAILTTP 1

 Score = 72.8 bits (177), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 53/167 (31%), Positives = 78/167 (46%), Gaps = 3/167 (1%)
 Frame = -1

Query: 508 DGVYSFEYYPSTPGKYSVAVTWGGHHIPKSPFEVQVGPEAGMQKVRAWGPGLHGGIVGRS 567
           DG Y+  Y P  P K++V+V +GG  +P SPF V V   +   KV+  GPG+  GI   S
Sbjct: 540 DGTYACRYMPLRPVKHTVSVNFGGVAVPNSPFRVHVAEPSDPSKVKISGPGVTNGIKTMS 361

Query: 568 AD-FVVESIGSEVGTLGFAIEGPS--QAKIEYDDQNDGSCDVKYWPKEPGEYAVHIMCDD 624
              F V+   +  G +   +         ++     DG+  V+Y PK PG Y V +   D
Sbjct: 360 PTYFTVDCKQAGPGDVAVGLTDGRGMDVPVKTTGNQDGTFTVEYEPKLPGTYTVMVYFAD 181

Query: 625 EDIKDSPYMAFIHPATGDYNPDLVQAYGPGLEKSGCTINNPAEFIVD 671
            ++  SP    + P     N D+      GL+ S   I  P+EF+VD
Sbjct: 180 VEVPSSPVKVKVEP-----NIDVSSIRVDGLD-SRVFIEAPSEFVVD 58

 Score = 72.0 bits (175), Expect = 3e-12,   Method: Compositional matrix adjust.
 Identities = 45/139 (32%), Positives = 66/139 (47%), Gaps = 3/139 (2%)
 Frame = -1

Query: 1005 KFIPREEGLFAVDVTYDGHPVPGSPYTVEASLPPDPTKVKAHGPGLEGGL-VGKPAEFTI 1063
            +++P       V V + G  VP SP+ V  + P DP+KVK  GPG+  G+    P  FT+
Sbjct: 522  RYMPLRPVKHTVSVNFGGVAVPNSPFRVHVAEPSDPSKVKISGPGVTNGIKTMSPTYFTV 343

Query: 1064 DTKXXXXXXXXXXVEG--PCEAKIECSDNGDGTCSVSYLPTKPGEYFVNILFEEVHIPGS 1121
            D K          +      +  ++ + N DGT +V Y P  PG Y V + F +V +P S
Sbjct: 342  DCKQAGPGDVAVGLTDGRGMDVPVKTTGNQDGTFTVEYEPKLPGTYTVMVYFADVEVPSS 163

Query: 1122 PFKADIEMPFDPSKVVASG 1140
            P K  +E   D S +   G
Sbjct: 162  PVKVKVEPNIDVSSIRVDG 106

 Score = 67.8 bits (164), Expect = 5e-11,   Method: Compositional matrix adjust.
 Identities = 44/127 (34%), Positives = 67/127 (52%), Gaps = 3/127 (2%)
 Frame = -1

Query: 1983 FIPREVGEHLVSIKKNGNHVANSPVSIMVVQSEIGDARRAKVYGQGLSEG-RTFEMSDFI 2041
            ++P    +H VS+   G  V NSP  + V  +E  D  + K+ G G++ G +T   + F 
Sbjct: 519  YMPLRPVKHTVSVNFGGVAVPNSPFRVHV--AEPSDPSKVKISGPGVTNGIKTMSPTYFT 346

Query: 2042 VDTRDAGYGGISLAVEGPSKVDI--QTEDLEDGTCKVSYFPTVPGVYIVSTKFADEHVPG 2099
            VD + AG G +++ +     +D+  +T   +DGT  V Y P +PG Y V   FAD  VP 
Sbjct: 345  VDCKQAGPGDVAVGLTDGRGMDVPVKTTGNQDGTFTVEYEPKLPGTYTVMVYFADVEVPS 166

Query: 2100 SPFTVKI 2106
            SP  VK+
Sbjct: 165  SPVKVKV 145

 Score = 63.2 bits (152), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 46/182 (25%), Positives = 80/182 (43%), Gaps = 3/182 (1%)
 Frame = -1

Query: 599 QNDGSCDVKYWPKEPGEYAVHIMCDDEDIKDSPYMAFIHPATGDYNPDLVQAYGPGLEKS 658
             DG+   +Y P  P ++ V +      + +SP+   +   +   +P  V+  GPG+  +
Sbjct: 546 NRDGTYACRYMPLRPVKHTVSVNFGGVAVPNSPFRVHVAEPS---DPSKVKISGPGV-TN 379

Query: 659 GCTINNPAEFIVDPKDAGSAPLKILAQDGEGQPIDIQMKSRMDGTYACSYTPLKAIKHTI 718
           G    +P  F VD K AG   + +   DG G  + ++     DGT+   Y P     +T+
Sbjct: 378 GIKTMSPTYFTVDCKQAGPGDVAVGLTDGRGMDVPVKTTGNQDGTFTVEYEPKLPGTYTV 199

Query: 719 AVVWGGVNIPHSPYRVNIGQGSHPQKVKVFGPGVERSGLKANEPTHFTVDCT---EAGEG 775
            V +  V +P SP +V +        ++V G     S +    P+ F VD +     G+G
Sbjct: 198 MVYFADVEVPSSPVKVKVEPNIDVSSIRVDG---LDSRVFIEAPSEFVVDASVLDPKGQG 28

Query: 776 DV 777
           +V
Sbjct: 27  EV 22

 Score = 61.2 bits (147), Expect = 6e-09,   Method: Compositional matrix adjust.
 Identities = 51/183 (27%), Positives = 85/183 (46%), Gaps = 3/183 (1%)
 Frame = -1

Query: 2169 SHCVRFVPQEMGVHTVSVKYRGQHVTGSPFQFTVGPLGEGGAHKVRAGGPGLERGEAGI- 2227
            ++  R++P     HTVSV + G  V  SPF+  V    +    KV+  GPG+  G   + 
Sbjct: 534  TYACRYMPLRPVKHTVSVNFGGVAVPNSPFRVHVAEPSD--PSKVKISGPGVTNGIKTMS 361

Query: 2228 PAEFSIWTREAGAGGLSIAVEGPSKAEITFDD--HKNGSCGVSYIAQEPGNYEVSIKFND 2285
            P  F++  ++AG G +++ +      ++      +++G+  V Y  + PG Y V + F D
Sbjct: 360  PTYFTVDCKQAGPGDVAVGLTDGRGMDVPVKTTGNQDGTFTVEYEPKLPGTYTVMVYFAD 181

Query: 2286 EHIPDSPYLVPVIAPSDDARCLTVLSLQESGLKVNQPASFAIRLNGAKGKIDAKVHSPSG 2345
              +P SP  V V  P+ D   + V  L +S + +  P+ F          +DA V  P G
Sbjct: 180  VEVPSSPVKVKV-EPNIDVSSIRVDGL-DSRVFIEAPSEFV---------VDASVLDPKG 34

Query: 2346 AVE 2348
              E
Sbjct: 33   QGE 25

 Score = 58.2 bits (139), Expect = 5e-08,   Method: Compositional matrix adjust.
 Identities = 45/135 (33%), Positives = 62/135 (45%), Gaps = 6/135 (4%)
 Frame = -1

Query: 2360 YAVRFIPHENGIHTIDVKFNGSHVVGSPFKVRVGEPGQAGNPALVSAYGAGLETGTTGIQ 2419
            YA R++P     HT+ V F G  V  SPF+V V EP    +P+ V   G G+  G   + 
Sbjct: 531  YACRYMPLRPVKHTVSVNFGGVAVPNSPFRVHVAEP---SDPSKVKISGPGVTNGIKTMS 361

Query: 2420 SEFF-INTTQAGPGTLSVTIEGPSKVKMDCQEIPEG-----YKVMYTPMAPGNYLIGVKY 2473
              +F ++  QAGPG ++V +       MD      G     + V Y P  PG Y + V Y
Sbjct: 360  PTYFTVDCKQAGPGDVAVGLT--DGRGMDVPVKTTGNQDGTFTVEYEPKLPGTYTVMV-Y 190

Query: 2474 GGPNHISRSPFKAKV 2488
                 +  SP K KV
Sbjct: 189  FADVEVPSSPVKVKV 145

 Score = 49.3 bits (116), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 29/76 (38%), Positives = 42/76 (55%)
 Frame = -1

Query: 273 QPAKFTVDTISAGQGDVMVFVEDPEGNKEEARVTPDSDKNKTYSVEYLPKVTGLHKVIVL 332
            P  FTVD   AG GDV V + D  G     + T   +++ T++VEY PK+ G + V+V 
Sbjct: 363 SPTYFTVDCKQAGPGDVAVGLTDGRGMDVPVKTT--GNQDGTFTVEYEPKLPGTYTVMVY 190

Query: 333 FAGQHISKSPFEVNVD 348
           FA   +  SP +V V+
Sbjct: 189 FADVEVPSSPVKVKVE 142

 Score = 46.2 bits (108), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 46/163 (28%), Positives = 69/163 (42%)
 Frame = -1

Query: 1667 NEDGTYDIFYTAAKPGTYVIYVRFGGVDIPNSPFTVMVSRVPSPEPALTSRSTSTCWKLG 1726
            N DGTY   Y   +P  + + V FGGV +PNSPF V V+     EP+  S+   +   + 
Sbjct: 546  NRDGTYACRYMPLRPVKHTVSVNFGGVAVPNSPFRVHVA-----EPSDPSKVKISGPGVT 382

Query: 1727 EGRAQAVGSWVTEEAYVPVSDMNGLGFKPFDLVIPFAVRKGEITGTVHMPSGKKATPEIV 1786
             G      ++ T        D    G  P D+ +     +G       M    K T    
Sbjct: 381  NGIKTMSPTYFT-------VDCKQAG--PGDVAVGLTDGRG-------MDVPVKTT---- 262

Query: 1787 DNKDGTVTVRYAPTEVGLHEMHIKYRGSHIPGNPLQFYVNYPN 1829
             N+DGT TV Y P   G + + + +    +P +P++  V  PN
Sbjct: 261  GNQDGTFTVEYEPKLPGTYTVMVYFADVEVPSSPVKVKVE-PN 136

 Score = 44.7 bits (104), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 33/134 (24%), Positives = 57/134 (42%), Gaps = 1/134 (0%)
 Frame = -1

Query: 2260 HKNGSCGVSYIAQEPGNYEVSIKFNDEHIPDSPYLVPVIAPSDDARCLTVLSLQESGLKV 2319
            +++G+    Y+   P  + VS+ F    +P+SP+ V V  PSD ++         +G+K 
Sbjct: 546  NRDGTYACRYMPLRPVKHTVSVNFGGVAVPNSPFRVHVAEPSDPSKVKISGPGVTNGIKT 367

Query: 2320 NQPASFAIRLNGA-KGKIDAKVHSPSGAVEECHVSELEPDKYAVRFIPHENGIHTIDVKF 2378
              P  F +    A  G +   +    G       +  +   + V + P   G +T+ V F
Sbjct: 366  MSPTYFTVDCKQAGPGDVAVGLTDGRGMDVPVKTTGNQDGTFTVEYEPKLPGTYTVMVYF 187

Query: 2379 NGSHVVGSPFKVRV 2392
                V  SP KV+V
Sbjct: 186  ADVEVPSSPVKVKV 145

 Score = 30.8 bits (68), Expect = 7.3,   Method: Compositional matrix adjust.
 Identities = 41/146 (28%), Positives = 53/146 (36%), Gaps = 11/146 (7%)
 Frame = -1

Query: 2070 EDGTCKVSYFPTVPGVYIVSTKFADEHVPGSPF-----------TVKISGEGRVRESITR 2118
             DGT    Y P  P  + VS  F    VP SPF            VKISG G V   I  
Sbjct: 543  RDGTYACRYMPLRPVKHTVSVNFGGVAVPNSPFRVHVAEPSDPSKVKISGPG-VTNGIKT 367

Query: 2119 TSRAPAVATVGSICDLNLKIPEINSSDMSAHVTSPSGHVTEAEIVPMGKNSHCVRFVPQE 2178
             S  P   TV   C       +    D++  +T   G     +       +  V + P+ 
Sbjct: 366  MS--PTYFTVD--CK------QAGPGDVAVGLTDGRGMDVPVKTTGNQDGTFTVEYEPKL 217

Query: 2179 MGVHTVSVKYRGQHVTGSPFQFTVGP 2204
             G +TV V +    V  SP +  V P
Sbjct: 216  PGTYTVMVYFADVEVPSSPVKVKVEP 139
>27230
          Length = 583

 Score = 73.6 bits (179), Expect(2) = 4e-21,   Method: Compositional matrix adjust.
 Identities = 36/82 (43%), Positives = 48/82 (58%)
 Frame = -1

Query: 1262 GGDHIKAQITNPSGASTECFVKDNADGTYQVEYTPFEKGFHVVEVTYDDVPIPNSPFKVA 1321
            G   ++A +T PSG   +  V +  DGTY V YTP E+G   ++VTY  +PIP SPF+V 
Sbjct: 247  GQGEVEAILTTPSGRKLQTLVDNMKDGTYPVLYTPMEEGPQSLDVTYKGIPIPGSPFQVN 68

Query: 1322 VTEGCQPSRVHAQGPGLKEAFT 1343
               G   +RV A GPGL+   T
Sbjct: 67   AVAGYDANRVRAYGPGLEGGLT 2

 Score = 48.9 bits (115), Expect(2) = 4e-21,   Method: Compositional matrix adjust.
 Identities = 31/85 (36%), Positives = 46/85 (54%), Gaps = 3/85 (3%)
 Frame = -2

Query: 1177 KAEVSIQNNKDGTYAVTYVPLTAGMYTLTMKYGGELVPHFPAWVKVEPA---IDTSGIKA 1233
            K++++  N  DGT  VTY+P   G Y + + +G + VP  P    + P+    D S I A
Sbjct: 513  KSKINCVNXDDGTVNVTYIPEFPGEYKVKVSHGDKPVPGSPFTALITPSELDPDVSSITA 334

Query: 1234 FGPGIEGKDVFREATTDFTVDSRPL 1258
             G GI  + VF EA ++F VD+  L
Sbjct: 333  SGYGISPEGVFIEAPSEFVVDASVL 259

 Score = 55.8 bits (133), Expect(2) = 2e-17,   Method: Compositional matrix adjust.
 Identities = 30/58 (51%), Positives = 38/58 (65%), Gaps = 1/58 (1%)
 Frame = -1

Query: 1471 VVDN-GDGTHTVTYTPSQEGPYIVSVKYADEEIPRSPFKVKVLPTYDASKVTASGPGL 1527
            +VDN  DGT+ V YTP +EGP  + V Y    IP SPF+V  +  YDA++V A GPGL
Sbjct: 190  LVDNMKDGTYPVLYTPMEEGPQSLDVTYKGIPIPGSPFQVNAVAGYDANRVRAYGPGL 17

 Score = 53.9 bits (128), Expect(2) = 2e-17,   Method: Compositional matrix adjust.
 Identities = 34/85 (40%), Positives = 48/85 (56%), Gaps = 4/85 (4%)
 Frame = -2

Query: 1368 PSESKINCRDNKDGSCSAEYIPFAPGDYDVNITYGGVHIPGSPFR---VPSKDVVDPSKV 1424
            P +SKINC +  DG+ +  YIP  PG+Y V +++G   +PGSPF     PS+   D S +
Sbjct: 519  PEKSKINCVNXDDGTVNVTYIPEFPGEYKVKVSHGDKPVPGSPFTALITPSELDPDVSSI 340

Query: 1425 KIAGPGLS-SCVRACIPQSFTVDSS 1448
              +G G+S   V    P  F VD+S
Sbjct: 339  TASGYGISPEGVFIEAPSEFVVDAS 265

 Score = 57.4 bits (137), Expect(2) = 3e-17,   Method: Compositional matrix adjust.
 Identities = 34/80 (42%), Positives = 44/80 (55%), Gaps = 3/80 (3%)
 Frame = -2

Query: 1469 VNVVDNGDGTHTVTYTPSQEGPYIVSVKYADEEIPRSPFKVKVLPTY---DASKVTASGP 1525
            +N V+  DGT  VTY P   G Y V V + D+ +P SPF   + P+    D S +TASG 
Sbjct: 504  INCVNXDDGTVNVTYIPEFPGEYKVKVSHGDKPVPGSPFTALITPSELDPDVSSITASGY 325

Query: 1526 GLSAYGVPASLPVEFAIDAR 1545
            G+S  GV    P EF +DA 
Sbjct: 324  GISPEGVFIEAPSEFVVDAS 265

 Score = 51.6 bits (122), Expect(2) = 3e-17,   Method: Compositional matrix adjust.
 Identities = 29/77 (37%), Positives = 43/77 (55%)
 Frame = -1

Query: 1548 GEGLLAVQITDQEGKPQRATVHDNKDGTYAVTYIPDKTGRYMIGVTYGGDNIPLSPYRIR 1607
            G+G +   +T   G+  +  V + KDGTY V Y P + G   + VTY G  IP SP+++ 
Sbjct: 247  GQGEVEAILTTPSGRKLQTLVDNMKDGTYPVLYTPMEEGPQSLDVTYKGIPIPGSPFQVN 68

Query: 1608 ATQTGDASKCLATGPGI 1624
            A    DA++  A GPG+
Sbjct: 67   AVAGYDANRVRAYGPGL 17

 Score = 57.0 bits (136), Expect(2) = 2e-16,   Method: Compositional matrix adjust.
 Identities = 30/83 (36%), Positives = 47/83 (56%)
 Frame = -2

Query: 589 PSQAKIEYDDQNDGSCDVKYWPKEPGEYAVHIMCDDEDIKDSPYMAFIHPATGDYNPDLV 648
           P ++KI   + +DG+ +V Y P+ PGEY V +   D+ +  SP+ A I P+  D +   +
Sbjct: 519 PEKSKINCVNXDDGTVNVTYIPEFPGEYKVKVSHGDKPVPGSPFTALITPSELDPDVSSI 340

Query: 649 QAYGPGLEKSGCTINNPAEFIVD 671
            A G G+   G  I  P+EF+VD
Sbjct: 339 TASGYGISPEGVFIEAPSEFVVD 271

 Score = 49.3 bits (116), Expect(2) = 2e-16,   Method: Compositional matrix adjust.
 Identities = 22/65 (33%), Positives = 38/65 (58%)
 Frame = -1

Query: 689 GQPIDIQMKSRMDGTYACSYTPLKAIKHTIAVVWGGVNIPHSPYRVNIGQGSHPQKVKVF 748
           G+ +   + +  DGTY   YTP++    ++ V + G+ IP SP++VN   G    +V+ +
Sbjct: 208 GRKLQTLVDNMKDGTYPVLYTPMEEGPQSLDVTYKGIPIPGSPFQVNAVAGYDANRVRAY 29

Query: 749 GPGVE 753
           GPG+E
Sbjct: 28  GPGLE 14

 Score = 51.6 bits (122), Expect(2) = 4e-15,   Method: Compositional matrix adjust.
 Identities = 26/67 (38%), Positives = 37/67 (55%)
 Frame = -1

Query: 1174 SGAKAEVSIQNNKDGTYAVTYVPLTAGMYTLTMKYGGELVPHFPAWVKVEPAIDTSGIKA 1233
            SG K +  + N KDGTY V Y P+  G  +L + Y G  +P  P  V      D + ++A
Sbjct: 211  SGRKLQTLVDNMKDGTYPVLYTPMEEGPQSLDVTYKGIPIPGSPFQVNAVAGYDANRVRA 32

Query: 1234 FGPGIEG 1240
            +GPG+EG
Sbjct: 31   YGPGLEG 11

 Score = 50.1 bits (118), Expect(2) = 4e-15,   Method: Compositional matrix adjust.
 Identities = 35/89 (39%), Positives = 48/89 (53%), Gaps = 5/89 (5%)
 Frame = -2

Query: 1080 PCEAKIECSDNGDGTCSVSYLPTKPGEYFVNILFEEVHIPGSPFKADI---EMPFDPSKV 1136
            P ++KI C +  DGT +V+Y+P  PGEY V +   +  +PGSPF A I   E+  D S +
Sbjct: 519  PEKSKINCVNXDDGTVNVTYIPEFPGEYKVKVSHGDKPVPGSPFTALITPSELDPDVSSI 340

Query: 1137 VASGPGL--EHGKVGEPGILCVDCSEAGP 1163
             ASG G+  E   +  P    VD S   P
Sbjct: 339  TASGYGISPEGVFIEAPSEFVVDASVLDP 253

 Score = 49.7 bits (117), Expect(2) = 2e-12,   Method: Compositional matrix adjust.
 Identities = 30/85 (35%), Positives = 46/85 (54%)
 Frame = -1

Query: 2139 PEINSSDMSAHVTSPSGHVTEAEIVPMGKNSHCVRFVPQEMGVHTVSVKYRGQHVTGSPF 2198
            P     ++ A +T+PSG   +  +  M   ++ V + P E G  ++ V Y+G  + GSPF
Sbjct: 256  PLKGQGEVEAILTTPSGRKLQTLVDNMKDGTYPVLYTPMEEGPQSLDVTYKGIPIPGSPF 77

Query: 2199 QFTVGPLGEGGAHKVRAGGPGLERG 2223
            Q  V  +    A++VRA GPGLE G
Sbjct: 76   Q--VNAVAGYDANRVRAYGPGLEGG 8

 Score = 43.1 bits (100), Expect(2) = 2e-12,   Method: Compositional matrix adjust.
 Identities = 22/49 (44%), Positives = 27/49 (55%)
 Frame = -2

Query: 2059 PSKVDIQTEDLEDGTCKVSYFPTVPGVYIVSTKFADEHVPGSPFTVKIS 2107
            P K  I   + +DGT  V+Y P  PG Y V     D+ VPGSPFT  I+
Sbjct: 519  PEKSKINCVNXDDGTVNVTYIPEFPGEYKVKVSHGDKPVPGSPFTALIT 373

 Score = 48.1 bits (113), Expect(2) = 1e-11,   Method: Compositional matrix adjust.
 Identities = 28/83 (33%), Positives = 40/83 (48%), Gaps = 3/83 (3%)
 Frame = -2

Query: 791 DEEDVDFDIIHNANDTFTVKYVPPAPGRYTIKVLFASQEIPASPFRVKVDPSH---DASK 847
           D E    + ++  + T  V Y+P  PG Y +KV    + +P SPF   + PS    D S 
Sbjct: 522 DPEKSKINCVNXDDGTVNVTYIPEFPGEYKVKVSHGDKPVPGSPFTALITPSELDPDVSS 343

Query: 848 VKAEGPGLSKAGVENGKPTHFTV 870
           + A G G+S  GV    P+ F V
Sbjct: 342 ITASGYGISPEGVFIEAPSEFVV 274

 Score = 41.6 bits (96), Expect(2) = 1e-11,   Method: Compositional matrix adjust.
 Identities = 22/55 (40%), Positives = 33/55 (60%), Gaps = 1/55 (1%)
 Frame = -1

Query: 898 IIDNY-DYSHTVKYTPTQQGNMQVLVTYGGDPIPKSPFTVGVAAPLDLSKIKING 951
           ++DN  D ++ V YTP ++G   + VTY G PIP SPF V   A  D ++++  G
Sbjct: 190 LVDNMKDGTYPVLYTPMEEGPQSLDVTYKGIPIPGSPFQVNAVAGYDANRVRAYG 26

 Score = 50.1 bits (118), Expect(2) = 2e-11,   Method: Compositional matrix adjust.
 Identities = 30/81 (37%), Positives = 39/81 (48%)
 Frame = -1

Query: 483 GSGELGVTVKGPKGLEELVKQKGFLDGVYSFEYYPSTPGKYSVAVTWGGHHIPKSPFEVQ 542
           G GE+   +  P G +         DG Y   Y P   G  S+ VT+ G  IP SPF+V 
Sbjct: 247 GQGEVEAILTTPSGRKLQTLVDNMKDGTYPVLYTPMEEGPQSLDVTYKGIPIPGSPFQVN 68

Query: 543 VGPEAGMQKVRAWGPGLHGGI 563
                   +VRA+GPGL GG+
Sbjct: 67  AVAGYDANRVRAYGPGLEGGL 5

 Score = 38.9 bits (89), Expect(2) = 2e-11,   Method: Compositional matrix adjust.
 Identities = 30/87 (34%), Positives = 44/87 (50%), Gaps = 3/87 (3%)
 Frame = -2

Query: 395 DPQGKNSVELLVEDRGNQVYRCVYKPVQPGPHVVKVSFAGDAIPKSPFGVQIGEA-CNPN 453
           DP+ K+ +  +  D G       Y P  PG + VKVS     +P SPF   I  +  +P+
Sbjct: 522 DPE-KSKINCVNXDDGT--VNVTYIPEFPGEYKVKVSHGDKPVPGSPFTALITPSELDPD 352

Query: 454 --ACRASGRGLQPKGVRIRETADFKVD 478
             +  ASG G+ P+GV I   ++F VD
Sbjct: 351 VSSITASGYGISPEGVFIEAPSEFVVD 271

 Score = 49.3 bits (116), Expect(2) = 4e-11,   Method: Compositional matrix adjust.
 Identities = 31/86 (36%), Positives = 46/86 (53%), Gaps = 1/86 (1%)
 Frame = -1

Query: 2332 AKGKIDAKVHSPSGAVEECHVSELEPDKYAVRFIPHENGIHTIDVKFNGSHVVGSPFKVR 2391
             +G+++A + +PSG   +  V  ++   Y V + P E G  ++DV + G  + GSPF+V 
Sbjct: 247  GQGEVEAILTTPSGRKLQTLVDNMKDGTYPVLYTPMEEGPQSLDVTYKGIPIPGSPFQVN 68

Query: 2392 VGEPGQAGNPA-LVSAYGAGLETGTT 2416
                  AG  A  V AYG GLE G T
Sbjct: 67   A----VAGYDANRVRAYGPGLEGGLT 2

 Score = 38.9 bits (89), Expect(2) = 4e-11,   Method: Compositional matrix adjust.
 Identities = 23/83 (27%), Positives = 43/83 (51%), Gaps = 5/83 (6%)
 Frame = -2

Query: 2250 PSKAEITFDDHKNGSCGVSYIAQEPGNYEVSIKFNDEHIPDSPYLVPVIAPSD---DARC 2306
            P K++I   +  +G+  V+YI + PG Y+V +   D+ +P SP+   +I PS+   D   
Sbjct: 519  PEKSKINCVNXDDGTVNVTYIPEFPGEYKVKVSHGDKPVPGSPFTA-LITPSELDPDVSS 343

Query: 2307 LTV--LSLQESGLKVNQPASFAI 2327
            +T     +   G+ +  P+ F +
Sbjct: 342  ITASGYGISPEGVFIEAPSEFVV 274

 Score = 45.4 bits (106), Expect(2) = 7e-11,   Method: Compositional matrix adjust.
 Identities = 22/59 (37%), Positives = 34/59 (57%)
 Frame = -1

Query: 1644 GKGKVTCVILTPDGTEAEADVIENEDGTYDIFYTAAKPGTYVIYVRFGGVDIPNSPFTV 1702
            G+G+V  ++ TP G + +  V   +DGTY + YT  + G   + V + G+ IP SPF V
Sbjct: 247  GQGEVEAILTTPSGRKLQTLVDNMKDGTYPVLYTPMEEGPQSLDVTYKGIPIPGSPFQV 71

 Score = 42.0 bits (97), Expect(2) = 7e-11,   Method: Compositional matrix adjust.
 Identities = 30/84 (35%), Positives = 45/84 (53%), Gaps = 6/84 (7%)
 Frame = -2

Query: 1563 PQRATVH--DNKDGTYAVTYIPDKTGRYMIGVTYGGDNIPLSPYRIRATQTG---DASKC 1617
            P+++ ++  +  DGT  VTYIP+  G Y + V++G   +P SP+    T +    D S  
Sbjct: 519  PEKSKINCVNXDDGTVNVTYIPEFPGEYKVKVSHGDKPVPGSPFTALITPSELDPDVSSI 340

Query: 1618 LATGPGIAPT-VKTGEEVGFVVDA 1640
             A+G GI+P  V       FVVDA
Sbjct: 339  TASGYGISPEGVFIEAPSEFVVDA 268

 Score = 46.2 bits (108), Expect(2) = 1e-10,   Method: Compositional matrix adjust.
 Identities = 27/66 (40%), Positives = 38/66 (57%), Gaps = 2/66 (3%)
 Frame = -1

Query: 1368 PSESKINCR-DN-KDGSCSAEYIPFAPGDYDVNITYGGVHIPGSPFRVPSKDVVDPSKVK 1425
            PS  K+    DN KDG+    Y P   G   +++TY G+ IPGSPF+V +    D ++V+
Sbjct: 214  PSGRKLQTLVDNMKDGTYPVLYTPMEEGPQSLDVTYKGIPIPGSPFQVNAVAGYDANRVR 35

Query: 1426 IAGPGL 1431
              GPGL
Sbjct: 34   AYGPGL 17

 Score = 40.4 bits (93), Expect(2) = 1e-10,   Method: Compositional matrix adjust.
 Identities = 30/101 (29%), Positives = 45/101 (44%)
 Frame = -2

Query: 1270 ITNPSGASTECFVKDNADGTYQVEYTPFEKGFHVVEVTYDDVPIPNSPFKVAVTEGCQPS 1329
            + +P  +   C   D  DGT  V Y P   G + V+V++ D P+P SPF   +T    PS
Sbjct: 528  LMDPEKSKINCVNXD--DGTVNVTYIPEFPGEYKVKVSHGDKPVPGSPFTALIT----PS 367

Query: 1330 RVHAQGPGLKEAFTNKSNVFTVVTRGAGIGGLGITVEGPSE 1370
             +               +V ++   G GI   G+ +E PSE
Sbjct: 366  ELDP-------------DVSSITASGYGISPEGVFIEAPSE 283

 Score = 45.4 bits (106), Expect(2) = 3e-10,   Method: Compositional matrix adjust.
 Identities = 22/55 (40%), Positives = 34/55 (61%)
 Frame = -1

Query: 1092 DGTCSVSYLPTKPGEYFVNILFEEVHIPGSPFKADIEMPFDPSKVVASGPGLEHG 1146
            DGT  V Y P + G   +++ ++ + IPGSPF+ +    +D ++V A GPGLE G
Sbjct: 172  DGTYPVLYTPMEEGPQSLDVTYKGIPIPGSPFQVNAVAGYDANRVRAYGPGLEGG 8

 Score = 39.7 bits (91), Expect(2) = 3e-10,   Method: Compositional matrix adjust.
 Identities = 24/64 (37%), Positives = 36/64 (56%), Gaps = 5/64 (7%)
 Frame = -2

Query: 1006 FIPREEGLFAVDVTYDGHPVPGSPYT---VEASLPPDPTKVKAHGPGL--EGGLVGKPAE 1060
            +IP   G + V V++   PVPGSP+T     + L PD + + A G G+  EG  +  P+E
Sbjct: 462  YIPEFPGEYKVKVSHGDKPVPGSPFTALITPSELDPDVSSITASGYGISPEGVFIEAPSE 283

Query: 1061 FTID 1064
            F +D
Sbjct: 282  FVVD 271

 Score = 61.2 bits (147), Expect = 5e-09,   Method: Compositional matrix adjust.
 Identities = 34/82 (41%), Positives = 50/82 (60%)
 Frame = -1

Query: 973  GQGKLDVTILSPSRKVVPCLVAPVAGRECSTAKFIPREEGLFAVDVTYDGHPVPGSPYTV 1032
            GQG+++  + +PS + +  LV  +         + P EEG  ++DVTY G P+PGSP+ V
Sbjct: 247  GQGEVEAILTTPSGRKLQTLVDNMK-DGTYPVLYTPMEEGPQSLDVTYKGIPIPGSPFQV 71

Query: 1033 EASLPPDPTKVKAHGPGLEGGL 1054
             A    D  +V+A+GPGLEGGL
Sbjct: 70   NAVAGYDANRVRAYGPGLEGGL 5

 Score = 60.8 bits (146), Expect = 6e-09,   Method: Compositional matrix adjust.
 Identities = 26/49 (53%), Positives = 36/49 (73%)
 Frame = -2

Query: 1870 PSKAEISCIDNKDGTCTVTYLPTLPGDYSILVKYNDKHIPGSPFTAKIT 1918
            P K++I+C++  DGT  VTY+P  PG+Y + V + DK +PGSPFTA IT
Sbjct: 519  PEKSKINCVNXDDGTVNVTYIPEFPGEYKVKVSHGDKPVPGSPFTALIT 373

 Score = 45.1 bits (105), Expect(2) = 6e-08,   Method: Compositional matrix adjust.
 Identities = 25/79 (31%), Positives = 42/79 (53%)
 Frame = -1

Query: 385 GVGDIGIEVEDPQGKNSVELLVEDRGNQVYRCVYKPVQPGPHVVKVSFAGDAIPKSPFGV 444
           G G++   +  P G+  ++ LV++  +  Y  +Y P++ GP  + V++ G  IP SPF V
Sbjct: 247 GQGEVEAILTTPSGRK-LQTLVDNMKDGTYPVLYTPMEEGPQSLDVTYKGIPIPGSPFQV 71

Query: 445 QIGEACNPNACRASGRGLQ 463
                 + N  RA G GL+
Sbjct: 70  NAVAGYDANRVRAYGPGLE 14

 Score = 32.3 bits (72), Expect(2) = 6e-08,   Method: Compositional matrix adjust.
 Identities = 21/81 (25%), Positives = 40/81 (49%), Gaps = 2/81 (2%)
 Frame = -2

Query: 299 NKEEARVTPDSDKNKTYSVEYLPKVTGLHKVIVLFAGQHISKSPFEVNVDKAQ--GDASK 356
           + E++++   +  + T +V Y+P+  G +KV V    + +  SPF   +  ++   D S 
Sbjct: 522 DPEKSKINCVNXDDGTVNVTYIPEFPGEYKVKVSHGDKPVPGSPFTALITPSELDPDVSS 343

Query: 357 VTAKGPGLETTGNIANKPTYF 377
           +TA G G+   G     P+ F
Sbjct: 342 ITASGYGISPEGVFIEAPSEF 280

 Score = 53.1 bits (126), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 31/80 (38%), Positives = 44/80 (55%), Gaps = 1/80 (1%)
 Frame = -1

Query: 1766 KGEITGTVHMPSGKKATPEIVDNKDGTVTVRYAPTEVGLHEMHIKYRGSHIPGNPLQF-Y 1824
            +GE+   +  PSG+K    + + KDGT  V Y P E G   + + Y+G  IPG+P Q   
Sbjct: 244  QGEVEAILTTPSGRKLQTLVDNMKDGTYPVLYTPMEEGPQSLDVTYKGIPIPGSPFQVNA 65

Query: 1825 VNYPNSGSVSAYGPGLVYGV 1844
            V   ++  V AYGPGL  G+
Sbjct: 64   VAGYDANRVRAYGPGLEGGL 5

 Score = 35.8 bits (81), Expect(2) = 5e-06,   Method: Compositional matrix adjust.
 Identities = 24/70 (34%), Positives = 35/70 (50%), Gaps = 2/70 (2%)
 Frame = -1

Query: 589 PSQAKIE--YDDQNDGSCDVKYWPKEPGEYAVHIMCDDEDIKDSPYMAFIHPATGDYNPD 646
           PS  K++   D+  DG+  V Y P E G  ++ +      I  SP+      A   Y+ +
Sbjct: 214 PSGRKLQTLVDNMKDGTYPVLYTPMEEGPQSLDVTYKGIPIPGSPFQVN---AVAGYDAN 44

Query: 647 LVQAYGPGLE 656
            V+AYGPGLE
Sbjct: 43  RVRAYGPGLE 14

 Score = 35.0 bits (79), Expect(2) = 5e-06,   Method: Compositional matrix adjust.
 Identities = 22/72 (30%), Positives = 36/72 (50%), Gaps = 5/72 (6%)
 Frame = -2

Query: 508 DGVYSFEYYPSTPGKYSVAVTWGGHHIPKSPFEVQVGP---EAGMQKVRAWGPGL--HGG 562
           DG  +  Y P  PG+Y V V+ G   +P SPF   + P   +  +  + A G G+   G 
Sbjct: 483 DGTVNVTYIPEFPGEYKVKVSHGDKPVPGSPFTALITPSELDPDVSSITASGYGISPEGV 304

Query: 563 IVGRSADFVVES 574
            +   ++FVV++
Sbjct: 303 FIEAPSEFVVDA 268

 Score = 50.4 bits (119), Expect = 9e-06,   Method: Compositional matrix adjust.
 Identities = 34/81 (41%), Positives = 44/81 (54%)
 Frame = -1

Query: 285 GQGDVMVFVEDPEGNKEEARVTPDSDKNKTYSVEYLPKVTGLHKVIVLFAGQHISKSPFE 344
           GQG+V   +  P G K +  V  D+ K+ TY V Y P   G   + V + G  I  SPF+
Sbjct: 247 GQGEVEAILTTPSGRKLQTLV--DNMKDGTYPVLYTPMEEGPQSLDVTYKGIPIPGSPFQ 74

Query: 345 VNVDKAQGDASKVTAKGPGLE 365
           VN   A  DA++V A GPGLE
Sbjct: 73  VNA-VAGYDANRVRAYGPGLE 14

 Score = 42.4 bits (98), Expect(2) = 5e-05,   Method: Compositional matrix adjust.
 Identities = 22/58 (37%), Positives = 33/58 (56%), Gaps = 1/58 (1%)
 Frame = -1

Query: 799 IIHNAND-TFTVKYVPPAPGRYTIKVLFASQEIPASPFRVKVDPSHDASKVKAEGPGL 855
           ++ N  D T+ V Y P   G  ++ V +    IP SPF+V     +DA++V+A GPGL
Sbjct: 190 LVDNMKDGTYPVLYTPMEEGPQSLDVTYKGIPIPGSPFQVNAVAGYDANRVRAYGPGL 17

 Score = 24.6 bits (52), Expect(2) = 5e-05,   Method: Compositional matrix adjust.
 Identities = 20/80 (25%), Positives = 31/80 (38%), Gaps = 3/80 (3%)
 Frame = -2

Query: 694 IQMKSRMDGTYACSYTPLKAIKHTIAVVWGGVNIPHSPYRVNIGQGSHPQKVKVF---GP 750
           I   +  DGT   +Y P    ++ + V  G   +P SP+   I        V      G 
Sbjct: 504 INCVNXDDGTVNVTYIPEFPGEYKVKVSHGDKPVPGSPFTALITPSELDPDVSSITASGY 325

Query: 751 GVERSGLKANEPTHFTVDCT 770
           G+   G+    P+ F VD +
Sbjct: 324 GISPEGVFIEAPSEFVVDAS 265

 Score = 35.4 bits (80), Expect(2) = 3e-04,   Method: Compositional matrix adjust.
 Identities = 23/57 (40%), Positives = 32/57 (56%), Gaps = 2/57 (3%)
 Frame = -1

Query: 1859 GEGGLDLAIEGPSKAEI-SCIDN-KDGTCTVTYLPTLPGDYSILVKYNDKHIPGSPF 1913
            G+G ++  +  PS  ++ + +DN KDGT  V Y P   G  S+ V Y    IPGSPF
Sbjct: 247  GQGEVEAILTTPSGRKLQTLVDNMKDGTYPVLYTPMEEGPQSLDVTYKGIPIPGSPF 77

 Score = 29.3 bits (64), Expect(2) = 3e-04,   Method: Compositional matrix adjust.
 Identities = 18/66 (27%), Positives = 33/66 (50%), Gaps = 4/66 (6%)
 Frame = -2

Query: 1779 KKATPEIVDNKDGTVTVRYAPTEVGLHEMHIKYRGSHIPGNPLQFYVN----YPNSGSVS 1834
            +K+    V+  DGTV V Y P   G +++ + +    +PG+P    +      P+  S++
Sbjct: 516  EKSKINCVNXDDGTVNVTYIPEFPGEYKVKVSHGDKPVPGSPFTALITPSELDPDVSSIT 337

Query: 1835 AYGPGL 1840
            A G G+
Sbjct: 336  ASGYGI 319

 Score = 30.8 bits (68), Expect(2) = 0.004,   Method: Compositional matrix adjust.
 Identities = 21/68 (30%), Positives = 34/68 (50%), Gaps = 3/68 (4%)
 Frame = -2

Query: 1979 IGISFIPREVGEHLVSIKKNGNHVANSPVSIMVVQSEIG-DARRAKVYGQGLS-EGRTFE 2036
            + +++IP   GE+ V +      V  SP + ++  SE+  D       G G+S EG   E
Sbjct: 474  VNVTYIPEFPGEYKVKVSHGDKPVPGSPFTALITPSELDPDVSSITASGYGISPEGVFIE 295

Query: 2037 M-SDFIVD 2043
              S+F+VD
Sbjct: 294  APSEFVVD 271

 Score = 30.0 bits (66), Expect(2) = 0.004,   Method: Compositional matrix adjust.
 Identities = 19/60 (31%), Positives = 29/60 (48%), Gaps = 2/60 (3%)
 Frame = -1

Query: 2048 GYGGISLAVEGPSKVDIQT--EDLEDGTCKVSYFPTVPGVYIVSTKFADEHVPGSPFTVK 2105
            G G +   +  PS   +QT  ++++DGT  V Y P   G   +   +    +PGSPF V 
Sbjct: 247  GQGEVEAILTTPSGRKLQTLVDNMKDGTYPVLYTPMEEGPQSLDVTYKGIPIPGSPFQVN 68

 Score = 35.0 bits (79), Expect = 0.35,   Method: Compositional matrix adjust.
 Identities = 16/53 (30%), Positives = 29/53 (54%)
 Frame = -2

Query: 1653 LTPDGTEAEADVIENEDGTYDIFYTAAKPGTYVIYVRFGGVDIPNSPFTVMVS 1705
            L  D  +++ + +  +DGT ++ Y    PG Y + V  G   +P SPFT +++
Sbjct: 531  LLMDPEKSKINCVNXDDGTVNVTYIPEFPGEYKVKVSHGDKPVPGSPFTALIT 373

 Score = 32.0 bits (71), Expect = 3.8,   Method: Compositional matrix adjust.
 Identities = 31/118 (26%), Positives = 43/118 (36%), Gaps = 3/118 (2%)
 Frame = -2

Query: 2441 PSKVKMDCQEIPEG-YKVMYTPMAPGNYLIGVKYGGPNHISRSPFKAKVTGQRLVSPGSA 2499
            P K K++C    +G   V Y P  PG Y + V +G    +  SPF A +T   L      
Sbjct: 519  PEKSKINCVNXDDGTVNVTYIPEFPGEYKVKVSHGD-KPVPGSPFTALITPSEL------ 361

Query: 2500 NETSSILVESVTRSSTETCYSAIPKSSSDASKVTSKGAGLSK--AFVGQKSSFLVDCS 2555
                                        D S +T+ G G+S    F+   S F+VD S
Sbjct: 360  --------------------------DPDVSSITASGYGISPEGVFIEAPSEFVVDAS 265

 Score = 31.2 bits (69), Expect = 6.1,   Method: Compositional matrix adjust.
 Identities = 13/28 (46%), Positives = 20/28 (71%)
 Frame = -2

Query: 2587 NVTYVVKERGDYVLAVKWGEEHIPGSPF 2614
            NVTY+ +  G+Y + V  G++ +PGSPF
Sbjct: 471  NVTYIPEFPGEYKVKVSHGDKPVPGSPF 388
>19002
          Length = 842

 Score = 94.7 bits (234), Expect = 4e-19,   Method: Composition-based stats.
 Identities = 62/195 (31%), Positives = 102/195 (52%), Gaps = 3/195 (1%)
 Frame = -2

Query: 46  DGLRLIALLEVLSQKRMHHKYHQRPTFRQMKLENVSVALEFLDHESIKLVSIDSKAIVDG 105
           DG  L+ LLEV  + R       +   R   LENV  AL FL  + + L ++ +  IVDG
Sbjct: 841 DGKMLMKLLEV--RVRGEIASDXKGKMRIHCLENVDKALTFLHEQRVHLENMGAHDIVDG 668

Query: 106 NLKLILGLVWTLILHYSISMPVWEDEGDDDAKKQTPKQRLLGWIQNKI---PYLPITNFN 162
           + +L LGL+WT+IL + I   + E+   D+++ ++ K  LL W Q K    P + + NF 
Sbjct: 667 SSRLTLGLIWTIILRFQIQDIMIEEV--DNSETKSAKDALLLWCQMKTAGYPNVNVRNFT 494

Query: 163 QNWQDGKALGALVDSCAPGLCPDWESWDPRKPVDNAREAMQQADDWLGVPQVITPEEIIH 222
            +W+DG A  A++    P L   ++       + N + A   A+D LG+  ++ PE++  
Sbjct: 493 TSWRDGLAFNAIIHKHRPDLV-QYDRLHKSSAIQNLQNAFTVAEDKLGLTALLEPEDVNV 317

Query: 223 PDVDEHSVMTYLSQF 237
              DE S++TY+  +
Sbjct: 316 EYPDEKSIITYVVTY 272
>05081
          Length = 981

 Score = 84.0 bits (206), Expect = 7e-16,   Method: Compositional matrix adjust.
 Identities = 43/94 (45%), Positives = 57/94 (60%), Gaps = 1/94 (1%)
 Frame = -1

Query: 2522 IPKSSSDASKVTSKGAGLSKAFVGQKSSFLVDCSKAGSNMLLIGVHGPT-TPCEEVSMKH 2580
            I +   DASKV +KG GL KAF  +  +F VD   AG  +L +G+  P+  P  E+S+K 
Sbjct: 975  IRRFRGDASKVVAKGQGLKKAFTNRLQTFQVDVKDAGEALLQVGMIAPSGKPEAELSVKK 796

Query: 2581 VGKQQYNVTYVVKERGDYVLAVKWGEEHIPGSPF 2614
                 Y + Y V E GD+VL VKWG++ IPGSPF
Sbjct: 795  TTNTSYTINYKVTEIGDHVLHVKWGDDDIPGSPF 694

 Score = 56.6 bits (135), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 35/96 (36%), Positives = 48/96 (50%)
 Frame = -1

Query: 347 VDKAQGDASKVTAKGPGLETTGNIANKPTYFDIYTAGAGVGDIGIEVEDPQGKNSVELLV 406
           + + +GDASKV AKG GL+      N+   F +    AG   + + +  P GK   EL V
Sbjct: 975 IRRFRGDASKVVAKGQGLKKA--FTNRLQTFQVDVKDAGEALLQVGMIAPSGKPEAELSV 802

Query: 407 EDRGNQVYRCVYKPVQPGPHVVKVSFAGDAIPKSPF 442
           +   N  Y   YK  + G HV+ V +  D IP SPF
Sbjct: 801 KKTTNTSYTINYKVTEIGDHVLHVKWGDDDIPGSPF 694

 Score = 55.8 bits (133), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 34/92 (36%), Positives = 50/92 (54%), Gaps = 1/92 (1%)
 Frame = -1

Query: 1612 GDASKCLATGPGIAPTVKTGEEVGFVVDAKTAGKGKVTCVILTPDGT-EAEADVIENEDG 1670
            GDASK +A G G+     T     F VD K AG+  +   ++ P G  EAE  V +  + 
Sbjct: 960  GDASKVVAKGQGLKKAF-TNRLQTFQVDVKDAGEALLQVGMIAPSGKPEAELSVKKTTNT 784

Query: 1671 TYDIFYTAAKPGTYVIYVRFGGVDIPNSPFTV 1702
            +Y I Y   + G +V++V++G  DIP SPF +
Sbjct: 783  SYTINYKVTEIGDHVLHVKWGDDDIPGSPFVL 688

 Score = 55.8 bits (133), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 32/88 (36%), Positives = 47/88 (53%), Gaps = 3/88 (3%)
 Frame = -1

Query: 1829 NSGSVSAYGPGLVYGVANKTATFTIVTEDAGEGGLDLAIEGPS---KAEISCIDNKDGTC 1885
            ++  V A G GL     N+  TF +  +DAGE  L + +  PS   +AE+S     + + 
Sbjct: 957  DASKVVAKGQGLKKAFTNRLQTFQVDVKDAGEALLQVGMIAPSGKPEAELSVKKTTNTSY 778

Query: 1886 TVTYLPTLPGDYSILVKYNDKHIPGSPF 1913
            T+ Y  T  GD+ + VK+ D  IPGSPF
Sbjct: 777  TINYKVTEIGDHVLHVKWGDDDIPGSPF 694

 Score = 52.8 bits (125), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 32/90 (35%), Positives = 48/90 (53%), Gaps = 1/90 (1%)
 Frame = -1

Query: 1516 DASKVTASGPGLSAYGVPASLPVEFAIDARDAGEGLLAVQITDQEGKPQ-RATVHDNKDG 1574
            DASKV A G GL       +    F +D +DAGE LL V +    GKP+   +V    + 
Sbjct: 957  DASKVVAKGQGLKK--AFTNRLQTFQVDVKDAGEALLQVGMIAPSGKPEAELSVKKTTNT 784

Query: 1575 TYAVTYIPDKTGRYMIGVTYGGDNIPLSPY 1604
            +Y + Y   + G +++ V +G D+IP SP+
Sbjct: 783  SYTINYKVTEIGDHVLHVKWGDDDIPGSPF 694

 Score = 51.6 bits (122), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 30/86 (34%), Positives = 49/86 (56%), Gaps = 3/86 (3%)
 Frame = -1

Query: 1329 SRVHAQGPGLKEAFTNKSNVFTVVTRGAGIGGLGITVEGPS---ESKINCRDNKDGSCSA 1385
            S+V A+G GLK+AFTN+   F V  + AG   L + +  PS   E++++ +   + S + 
Sbjct: 951  SKVVAKGQGLKKAFTNRLQTFQVDVKDAGEALLQVGMIAPSGKPEAELSVKKTTNTSYTI 772

Query: 1386 EYIPFAPGDYDVNITYGGVHIPGSPF 1411
             Y     GD+ +++ +G   IPGSPF
Sbjct: 771  NYKVTEIGDHVLHVKWGDDDIPGSPF 694

 Score = 51.6 bits (122), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 31/89 (34%), Positives = 50/89 (56%), Gaps = 1/89 (1%)
 Frame = -1

Query: 1420 DPSKVKIAGPGLSSCVRACIPQSFTVDSSKAGLAPLEVRVLGPRGLVEP-VNVVDNGDGT 1478
            D SKV   G GL       + Q+F VD   AG A L+V ++ P G  E  ++V    + +
Sbjct: 957  DASKVVAKGQGLKKAFTNRL-QTFQVDVKDAGEALLQVGMIAPSGKPEAELSVKKTTNTS 781

Query: 1479 HTVTYTPSQEGPYIVSVKYADEEIPRSPF 1507
            +T+ Y  ++ G +++ VK+ D++IP SPF
Sbjct: 780  YTINYKVTEIGDHVLHVKWGDDDIPGSPF 694

 Score = 48.9 bits (115), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 26/91 (28%), Positives = 48/91 (52%), Gaps = 3/91 (3%)
 Frame = -1

Query: 2017 GDARRAKVYGQGLSEGRTFEMSDFIVDTRDAGYGGISLAVEGPS---KVDIQTEDLEDGT 2073
            GDA +    GQGL +  T  +  F VD +DAG   + + +  PS   + ++  +   + +
Sbjct: 960  GDASKVVAKGQGLKKAFTNRLQTFQVDVKDAGEALLQVGMIAPSGKPEAELSVKKTTNTS 781

Query: 2074 CKVSYFPTVPGVYIVSTKFADEHVPGSPFTV 2104
              ++Y  T  G +++  K+ D+ +PGSPF +
Sbjct: 780  YTINYKVTEIGDHVLHVKWGDDDIPGSPFVL 688

 Score = 43.1 bits (100), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 29/86 (33%), Positives = 44/86 (51%), Gaps = 1/86 (1%)
 Frame = -1

Query: 648 VQAYGPGLEKSGCTINNPAEFIVDPKDAGSAPLKILAQDGEGQP-IDIQMKSRMDGTYAC 706
           V A G GL+K+    N    F VD KDAG A L++      G+P  ++ +K   + +Y  
Sbjct: 945 VVAKGQGLKKAFT--NRLQTFQVDVKDAGEALLQVGMIAPSGKPEAELSVKKTTNTSYTI 772

Query: 707 SYTPLKAIKHTIAVVWGGVNIPHSPY 732
           +Y   +   H + V WG  +IP SP+
Sbjct: 771 NYKVTEIGDHVLHVKWGDDDIPGSPF 694

 Score = 39.3 bits (90), Expect = 0.020,   Method: Compositional matrix adjust.
 Identities = 33/97 (34%), Positives = 42/97 (43%), Gaps = 5/97 (5%)
 Frame = -1

Query: 1227 DTSGIKAFGPGIEGKDVFREATTDFTVDSR----PLTQVGGDHIKAQITNPSGA-STECF 1281
            D S + A G G+  K  F      F VD +     L QVG       +  PSG    E  
Sbjct: 957  DASKVVAKGQGL--KKAFTNRLQTFQVDVKDAGEALLQVG-------MIAPSGKPEAELS 805

Query: 1282 VKDNADGTYQVEYTPFEKGFHVVEVTYDDVPIPNSPF 1318
            VK   + +Y + Y   E G HV+ V + D  IP SPF
Sbjct: 804  VKKTTNTSYTINYKVTEIGDHVLHVKWGDDDIPGSPF 694

 Score = 38.9 bits (89), Expect = 0.028,   Method: Compositional matrix adjust.
 Identities = 22/88 (25%), Positives = 42/88 (47%), Gaps = 3/88 (3%)
 Frame = -1

Query: 1039 DPTKVKAHGPGLEGGLVGKPAEFTIDTKXXXXXXXXXXVEGPC---EAKIECSDNGDGTC 1095
            D +KV A G GL+     +   F +D K          +  P    EA++      + + 
Sbjct: 957  DASKVVAKGQGLKKAFTNRLQTFQVDVKDAGEALLQVGMIAPSGKPEAELSVKKTTNTSY 778

Query: 1096 SVSYLPTKPGEYFVNILFEEVHIPGSPF 1123
            +++Y  T+ G++ +++ + +  IPGSPF
Sbjct: 777  TINYKVTEIGDHVLHVKWGDDDIPGSPF 694

 Score = 37.4 bits (85), Expect = 0.089,   Method: Compositional matrix adjust.
 Identities = 28/84 (33%), Positives = 39/84 (46%), Gaps = 1/84 (1%)
 Frame = -1

Query: 457 ASGRGLQPKGVRIRETADFKVDTKAAGSGELGVTVKGPKGL-EELVKQKGFLDGVYSFEY 515
           A G+GL+       +T  F+VD K AG   L V +  P G  E  +  K   +  Y+  Y
Sbjct: 939 AKGQGLKKAFTNRLQT--FQVDVKDAGEALLQVGMIAPSGKPEAELSVKKTTNTSYTINY 766

Query: 516 YPSTPGKYSVAVTWGGHHIPKSPF 539
             +  G + + V WG   IP SPF
Sbjct: 765 KVTEIGDHVLHVKWGDDDIPGSPF 694

 Score = 35.0 bits (79), Expect = 0.38,   Method: Compositional matrix adjust.
 Identities = 23/92 (25%), Positives = 42/92 (45%)
 Frame = -1

Query: 744 KVKVFGPGVERSGLKANEPTHFTVDCTEAGEGDVSVGIKCDARVLSDDEEDVDFDIIHNA 803
           KV   G G++++    N    F VD  +AGE  + VG+     +    + + +  +    
Sbjct: 948 KVVAKGQGLKKAF--TNRLQTFQVDVKDAGEALLQVGM-----IAPSGKPEAELSVKKTT 790

Query: 804 NDTFTVKYVPPAPGRYTIKVLFASQEIPASPF 835
           N ++T+ Y     G + + V +   +IP SPF
Sbjct: 789 NTSYTINYKVTEIGDHVLHVKWGDDDIPGSPF 694

 Score = 35.0 bits (79), Expect = 0.42,   Method: Compositional matrix adjust.
 Identities = 17/47 (36%), Positives = 27/47 (57%), Gaps = 1/47 (2%)
 Frame = -1

Query: 1776 PSGK-KATPEIVDNKDGTVTVRYAPTEVGLHEMHIKYRGSHIPGNPL 1821
            PSGK +A   +    + + T+ Y  TE+G H +H+K+    IPG+P 
Sbjct: 834  PSGKPEAELSVKKTTNTSYTINYKVTEIGDHVLHVKWGDDDIPGSPF 694

 Score = 33.1 bits (74), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 23/86 (26%), Positives = 38/86 (44%), Gaps = 3/86 (3%)
 Frame = -1

Query: 551 KVRAWGPGLHGGIVGRSADFVVESIGSEVGTLGFAIEGPS---QAKIEYDDQNDGSCDVK 607
           KV A G GL      R   F V+   +    L   +  PS   +A++      + S  + 
Sbjct: 948 KVVAKGQGLKKAFTNRLQTFQVDVKDAGEALLQVGMIAPSGKPEAELSVKKTTNTSYTIN 769

Query: 608 YWPKEPGEYAVHIMCDDEDIKDSPYM 633
           Y   E G++ +H+   D+DI  SP++
Sbjct: 768 YKVTEIGDHVLHVKWGDDDIPGSPFV 691
>19147
          Length = 474

 Score = 65.1 bits (157), Expect = 4e-10,   Method: Composition-based stats.
 Identities = 37/100 (37%), Positives = 60/100 (60%), Gaps = 3/100 (3%)
 Frame = +1

Query: 86  FLDHESIKLVSIDSKAIVDGNLKLILGLVWTLILHYSISMPVWEDEGDDDAKKQTPKQRL 145
           ++  + +KLVSI ++ IVDGN+K+ LG++WT+IL ++I         D   ++ T K+ L
Sbjct: 49  YIASKGVKLVSIGAEEIVDGNVKMTLGMIWTIILRFAIQ--------DITVEELTAKEGL 204

Query: 146 LGWIQNKI-PY--LPITNFNQNWQDGKALGALVDSCAPGL 182
           L W Q K  PY  + + NF+ +++DG A  AL+    P L
Sbjct: 205 LLWCQRKTAPYKNVNVQNFHLSFKDGLAFCALIHRHRPEL 324
>19154
          Length = 512

 Score = 63.9 bits (154), Expect = 9e-10,   Method: Compositional matrix adjust.
 Identities = 46/145 (31%), Positives = 71/145 (48%), Gaps = 1/145 (0%)
 Frame = +2

Query: 1250 DFTVDSRPLTQVGGDHIKAQITNPSGASTECFVKDNADGTYQVEYTPFEKGFHVVEVTYD 1309
            DF+V++   ++ G      +I +PSG S    V + +   Y + Y P E G H + +TY+
Sbjct: 74   DFSVET---SRSGKCEQTVRIVSPSGQSVPVDVTETSTYGYNITYQPSESGQHRIFLTYN 244

Query: 1310 DVPIPNSPFKVAVTEGCQPSRVHAQGPGLKEAFTNKSNVFTVVTRGAGIGGLGITVEGP- 1368
             + +P SPF   ++EG  P    A G GL     +K+ +F +  RG   G   + V+GP 
Sbjct: 245  SLELPGSPFTQEISEGVLPP---AYGEGLHRGEEDKAAIFYIDARGL-TGEPSVQVDGPN 412

Query: 1369 SESKINCRDNKDGSCSAEYIPFAPG 1393
            S +K +     DG  S  YIP   G
Sbjct: 413  SIAKCSIEAQPDGQYSVTYIPVEVG 487

 Score = 58.2 bits (139), Expect = 4e-08,   Method: Compositional matrix adjust.
 Identities = 48/148 (32%), Positives = 73/148 (49%), Gaps = 4/148 (2%)
 Frame = +2

Query: 1443 FTVDSSKAGLAPLEVRVLGPRGLVEPVNVVDNGDGTHTVTYTPSQEGPYIVSVKYADEEI 1502
            F+V++S++G     VR++ P G   PV+V +     + +TY PS+ G + + + Y   E+
Sbjct: 77   FSVETSRSGKCEQTVRIVSPSGQSVPVDVTETSTYGYNITYQPSESGQHRIFLTYNSLEL 256

Query: 1503 PRSPFKVK----VLPTYDASKVTASGPGLSAYGVPASLPVEFAIDARDAGEGLLAVQITD 1558
            P SPF  +    VLP        A G GL   G      + F IDAR    G  +VQ+ D
Sbjct: 257  PGSPFTQEISEGVLP-------PAYGEGLHR-GEEDKAAI-FYIDARGL-TGEPSVQV-D 403

Query: 1559 QEGKPQRATVHDNKDGTYAVTYIPDKTG 1586
                  + ++    DG Y+VTYIP + G
Sbjct: 404  GPNSIAKCSIEAQPDGQYSVTYIPVEVG 487

 Score = 53.1 bits (126), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 44/142 (30%), Positives = 66/142 (46%), Gaps = 1/142 (0%)
 Frame = +2

Query: 474 DFKVDTKAAGSGELGVTVKGPKGLEELVKQKGFLDGVYSFEYYPSTPGKYSVAVTWGGHH 533
           DF V+T  +G  E  V +  P G    V         Y+  Y PS  G++ + +T+    
Sbjct: 74  DFSVETSRSGKCEQTVRIVSPSGQSVPVDVTETSTYGYNITYQPSESGQHRIFLTYNSLE 253

Query: 534 IPKSPFEVQVGPEAGMQKVRAWGPGLHGGIVGRSADFVVESIGSEVGTLGFAIEGP-SQA 592
           +P SPF  ++  E  +    A+G GLH G   ++A F +++ G   G     ++GP S A
Sbjct: 254 LPGSPFTQEIS-EGVLPP--AYGEGLHRGEEDKAAIFYIDARGL-TGEPSVQVDGPNSIA 421

Query: 593 KIEYDDQNDGSCDVKYWPKEPG 614
           K   + Q DG   V Y P E G
Sbjct: 422 KCSIEAQPDGQYSVTYIPVEVG 487

 Score = 51.6 bits (122), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 51/151 (33%), Positives = 73/151 (48%), Gaps = 8/151 (5%)
 Frame = +2

Query: 963  EFAIDTNGAGGQGKLDVTILSPSRKVVPCLVAPVAGRECST----AKFIPREEGLFAVDV 1018
            +F+++T+ +G + +  V I+SPS + VP  V      E ST      + P E G   + +
Sbjct: 74   DFSVETSRSG-KCEQTVRIVSPSGQSVPVDVT-----ETSTYGYNITYQPSESGQHRIFL 235

Query: 1019 TYDGHPVPGSPYTVEAS---LPPDPTKVKAHGPGLEGGLVGKPAEFTIDTKXXXXXXXXX 1075
            TY+   +PGSP+T E S   LPP      A+G GL  G   K A F ID +         
Sbjct: 236  TYNSLELPGSPFTQEISEGVLPP------AYGEGLHRGEEDKAAIFYIDAR-GLTGEPSV 394

Query: 1076 XVEGPCE-AKIECSDNGDGTCSVSYLPTKPG 1105
             V+GP   AK       DG  SV+Y+P + G
Sbjct: 395  QVDGPNSIAKCSIEAQPDGQYSVTYIPVEVG 487

 Score = 50.4 bits (119), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 39/145 (26%), Positives = 63/145 (43%), Gaps = 1/145 (0%)
 Frame = +2

Query: 1937 LGSAADFLLDISETDLSTLTASIKAPSGRDEPCLLKRLPNNHIGISFIPREVGEHLVSIK 1996
            L +  DF ++ S +     T  I +PSG+  P  +         I++ P E G+H + + 
Sbjct: 59   LANWLDFSVETSRSGKCEQTVRIVSPSGQSVPVDVTETSTYGYNITYQPSESGQHRIFLT 238

Query: 1997 KNGNHVANSPVSIMVVQSEIGDARRAKVYGQGLSEGRTFEMSDFIVDTRDAGYGGISLAV 2056
             N   +  SP +      EI +      YG+GL  G   + + F +D R    G  S+ V
Sbjct: 239  YNSLELPGSPFT-----QEISEGVLPPAYGEGLHRGEEDKAAIFYIDARGLT-GEPSVQV 400

Query: 2057 EGPSKV-DIQTEDLEDGTCKVSYFP 2080
            +GP+ +     E   DG   V+Y P
Sbjct: 401  DGPNSIAKCSIEAQPDGQYSVTYIP 475

 Score = 49.7 bits (117), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 32/107 (29%), Positives = 55/107 (51%), Gaps = 2/107 (1%)
 Frame = +2

Query: 1096 SVSYLPTKPGEYFVNILFEEVHIPGSPFKADIEMPFDPSKVVASGPGLEHGKVGEPGILC 1155
            +++Y P++ G++ + + +  + +PGSPF  +I     P    A G GL  G+  +  I  
Sbjct: 188  NITYQPSESGQHRIFLTYNSLELPGSPFTQEISEGVLPP---AYGEGLHRGEEDKAAIFY 358

Query: 1156 VDCSEAGPGTLGLEAVSDSG--AKAEVSIQNNKDGTYAVTYVPLTAG 1200
            +D      G  G  +V   G  + A+ SI+   DG Y+VTY+P+  G
Sbjct: 359  IDAR----GLTGEPSVQVDGPNSIAKCSIEAQPDGQYSVTYIPVEVG 487

 Score = 47.0 bits (110), Expect = 9e-05,   Method: Compositional matrix adjust.
 Identities = 41/133 (30%), Positives = 63/133 (47%), Gaps = 6/133 (4%)
 Frame = +2

Query: 1765 RKGEITGTVHM--PSGKKATPEIVDNKDGTVTVRYAPTEVGLHEMHIKYRGSHIPGNPLQ 1822
            R G+   TV +  PSG+    ++ +       + Y P+E G H + + Y    +PG+P  
Sbjct: 95   RSGKCEQTVRIVSPSGQSVPVDVTETSTYGYNITYQPSESGQHRIFLTYNSLELPGSP-- 268

Query: 1823 FYVNYPNSGSV-SAYGPGLVYGVANKTATFTIVTEDAG--EGGLDLAIEGP-SKAEISCI 1878
             +    + G +  AYG GL  G  +K A F I   DA    G   + ++GP S A+ S  
Sbjct: 269  -FTQEISEGVLPPAYGEGLHRGEEDKAAIFYI---DARGLTGEPSVQVDGPNSIAKCSIE 436

Query: 1879 DNKDGTCTVTYLP 1891
               DG  +VTY+P
Sbjct: 437  AQPDGQYSVTYIP 475

 Score = 46.6 bits (109), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 34/112 (30%), Positives = 56/112 (50%)
 Frame = +2

Query: 868 FTVHTKGAGKAPLNVQFSSPLPGEAVKDLDIIDNYDYSHTVKYTPTQQGNMQVLVTYGGD 927
           F+V T  +GK    V+  SP  G++V  +D+ +   Y + + Y P++ G  ++ +TY   
Sbjct: 77  FSVETSRSGKCEQTVRIVSP-SGQSVP-VDVTETSTYGYNITYQPSESGQHRIFLTYNSL 250

Query: 928 PIPKSPFTVGVAAPLDLSKIKINGLENRVEVGKDQEFAIDTNGAGGQGKLDV 979
            +P SPFT  ++  + L      GL +R E  K   F ID  G  G+  + V
Sbjct: 251 ELPGSPFTQEISEGV-LPPAYGEGL-HRGEEDKAAIFYIDARGLTGEPSVQV 400

 Score = 44.3 bits (103), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 40/141 (28%), Positives = 65/141 (46%)
 Frame = +2

Query: 377 FDIYTAGAGVGDIGIEVEDPQGKNSVELLVEDRGNQVYRCVYKPVQPGPHVVKVSFAGDA 436
           F + T+ +G  +  + +  P G+ SV + V +     Y   Y+P + G H + +++    
Sbjct: 77  FSVETSRSGKCEQTVRIVSPSGQ-SVPVDVTETSTYGYNITYQPSESGQHRIFLTYNSLE 253

Query: 437 IPKSPFGVQIGEACNPNACRASGRGLQPKGVRIRETADFKVDTKAAGSGELGVTVKGPKG 496
           +P SPF  +I E   P    A G GL  +G   +  A F +D +   +GE  V V GP  
Sbjct: 254 LPGSPFTQEISEGVLPP---AYGEGLH-RGEEDK-AAIFYIDARGL-TGEPSVQVDGPNS 415

Query: 497 LEELVKQKGFLDGVYSFEYYP 517
           + +    +   DG YS  Y P
Sbjct: 416 IAK-CSIEAQPDGQYSVTYIP 475

 Score = 41.6 bits (96), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 36/154 (23%), Positives = 69/154 (44%)
 Frame = +2

Query: 765 FTVDCTEAGEGDVSVGIKCDARVLSDDEEDVDFDIIHNANDTFTVKYVPPAPGRYTIKVL 824
           F+V+ + +G+ + +V      R++S   + V  D+   +   + + Y P   G++ I + 
Sbjct: 77  FSVETSRSGKCEQTV------RIVSPSGQSVPVDVTETSTYGYNITYQPSESGQHRIFLT 238

Query: 825 FASQEIPASPFRVKVDPSHDASKVKAEGPGLSKAGVENGKPTHFTVHTKGAGKAPLNVQF 884
           + S E+P SPF  ++    +     A G GL +   E  K   F +  +G    P +VQ 
Sbjct: 239 YNSLELPGSPFTQEIS---EGVLPPAYGEGLHRG--EEDKAAIFYIDARGLTGEP-SVQV 400

Query: 885 SSPLPGEAVKDLDIIDNYDYSHTVKYTPTQQGNM 918
             P    ++    I    D  ++V Y P + G++
Sbjct: 401 DGP---NSIAKCSIEAQPDGQYSVTYIPVEVGSV 493

 Score = 40.8 bits (94), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 37/142 (26%), Positives = 66/142 (46%), Gaps = 3/142 (2%)
 Frame = +2

Query: 1851 FTIVTEDAGEGGLDLAIEGPSKAEISCIDNKDGTC--TVTYLPTLPGDYSILVKYNDKHI 1908
            F++ T  +G+    + I  PS   +     +  T    +TY P+  G + I + YN   +
Sbjct: 77   FSVETSRSGKCEQTVRIVSPSGQSVPVDVTETSTYGYNITYQPSESGQHRIFLTYNSLEL 256

Query: 1909 PGSPFTAKIT-GRLCCFFSDDNRRCSQVKLGSAADFLLDISETDLSTLTASIKAPSGRDE 1967
            PGSPFT +I+ G L   + +   R  + K   AA F +D +       +  +  P+   +
Sbjct: 257  PGSPFTQEISEGVLPPAYGEGLHRGEEDK---AAIFYID-ARGLTGEPSVQVDGPNSIAK 424

Query: 1968 PCLLKRLPNNHIGISFIPREVG 1989
             C ++  P+    +++IP EVG
Sbjct: 425  -CSIEAQPDGQYSVTYIPVEVG 487

 Score = 37.0 bits (84), Expect = 0.10,   Method: Compositional matrix adjust.
 Identities = 23/95 (24%), Positives = 46/95 (48%), Gaps = 2/95 (2%)
 Frame = +2

Query: 662 INNPAEFIVDPKDAGSA--PLKILAQDGEGQPIDIQMKSRMDGTYACSYTPLKAIKHTIA 719
           + N  +F V+   +G     ++I++  G+  P+D+   S     Y  +Y P ++ +H I 
Sbjct: 59  LANWLDFSVETSRSGKCEQTVRIVSPSGQSVPVDVTETSTYG--YNITYQPSESGQHRIF 232

Query: 720 VVWGGVNIPHSPYRVNIGQGSHPQKVKVFGPGVER 754
           + +  + +P SP+   I +G  P     +G G+ R
Sbjct: 233 LTYNSLELPGSPFTQEISEGVLP---PAYGEGLHR 328

 Score = 35.0 bits (79), Expect = 0.44,   Method: Compositional matrix adjust.
 Identities = 17/67 (25%), Positives = 35/67 (52%)
 Frame = +2

Query: 1538 VEFAIDARDAGEGLLAVQITDQEGKPQRATVHDNKDGTYAVTYIPDKTGRYMIGVTYGGD 1597
            ++F+++   +G+    V+I    G+     V +     Y +TY P ++G++ I +TY   
Sbjct: 71   LDFSVETSRSGKCEQTVRIVSPSGQSVPVDVTETSTYGYNITYQPSESGQHRIFLTYNSL 250

Query: 1598 NIPLSPY 1604
             +P SP+
Sbjct: 251  ELPGSPF 271

 Score = 33.9 bits (76), Expect = 0.92,   Method: Compositional matrix adjust.
 Identities = 37/156 (23%), Positives = 64/156 (41%), Gaps = 1/156 (0%)
 Frame = +2

Query: 270 MVKQPAKFTVDTISAGQGDVMVFVEDPEGNKEEARVTPDSDKNKTYSVEYLPKVTGLHKV 329
           M+     F+V+T  +G+ +  V +  P G      VT  S     Y++ Y P  +G H++
Sbjct: 56  MLANWLDFSVETSRSGKCEQTVRIVSPSGQSVPVDVTETSTYG--YNITYQPSESGQHRI 229

Query: 330 IVLFAGQHISKSPFEVNVDKAQGDASKVTAKGPGLETTGNIANKPTYFDIYTAGAGVGDI 389
            + +    +  SPF   +     +     A G GL           Y D   A    G+ 
Sbjct: 230 FLTYNSLELPGSPFTQEIS----EGVLPPAYGEGLHRGEEDKAAIFYID---ARGLTGEP 388

Query: 390 GIEVEDPQGKNSV-ELLVEDRGNQVYRCVYKPVQPG 424
            ++V+ P   NS+ +  +E + +  Y   Y PV+ G
Sbjct: 389 SVQVDGP---NSIAKCSIEAQPDGQYSVTYIPVEVG 487

 Score = 33.5 bits (75), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 17/65 (26%), Positives = 30/65 (46%)
 Frame = +2

Query: 2550 FLVDCSKAGSNMLLIGVHGPTTPCEEVSMKHVGKQQYNVTYVVKERGDYVLAVKWGEEHI 2609
            F V+ S++G     + +  P+     V +       YN+TY   E G + + + +    +
Sbjct: 77   FSVETSRSGKCEQTVRIVSPSGQSVPVDVTETSTYGYNITYQPSESGQHRIFLTYNSLEL 256

Query: 2610 PGSPF 2614
            PGSPF
Sbjct: 257  PGSPF 271

 Score = 31.2 bits (69), Expect = 5.2,   Method: Compositional matrix adjust.
 Identities = 32/106 (30%), Positives = 52/106 (49%), Gaps = 3/106 (2%)
 Frame = +2

Query: 1387 YIPFAPGDYDVNITYGGVHIPGSPF-RVPSKDVVDPSKVKIAGPGLSSCV--RACIPQSF 1443
            Y P   G + + +TY  + +PGSPF +  S+ V+ P+     G GL      +A I   F
Sbjct: 197  YQPSESGQHRIFLTYNSLELPGSPFTQEISEGVLPPAY----GEGLHRGEEDKAAI---F 355

Query: 1444 TVDSSKAGLAPLEVRVLGPRGLVEPVNVVDNGDGTHTVTYTPSQEG 1489
             +D+      P  V+V GP  + +  ++    DG ++VTY P + G
Sbjct: 356  YIDARGLTGEP-SVQVDGPNSIAK-CSIEAQPDGQYSVTYIPVEVG 487

 Score = 30.4 bits (67), Expect = 9.1,   Method: Compositional matrix adjust.
 Identities = 20/71 (28%), Positives = 35/71 (49%), Gaps = 2/71 (2%)
 Frame = +2

Query: 2039 DFIVDTRDAGYGGISLAVEGPSKVDIQTEDLEDGTC--KVSYFPTVPGVYIVSTKFADEH 2096
            DF V+T  +G    ++ +  PS   +  +  E  T    ++Y P+  G + +   +    
Sbjct: 74   DFSVETSRSGKCEQTVRIVSPSGQSVPVDVTETSTYGYNITYQPSESGQHRIFLTYNSLE 253

Query: 2097 VPGSPFTVKIS 2107
            +PGSPFT +IS
Sbjct: 254  LPGSPFTQEIS 286
>29755
          Length = 460

 Score = 62.0 bits (149), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 25/45 (55%), Positives = 37/45 (82%)
 Frame = +3

Query: 2574 EEVSMKHVGKQQYNVTYVVKERGDYVLAVKWGEEHIPGSPFHVTV 2618
            +E+++K+VG  QYN+ Y VK++G Y+L V+WG+E+IPGSPF V V
Sbjct: 3    DELTVKYVGSGQYNINYTVKQQGSYMLIVRWGDENIPGSPFAVDV 137

 Score = 42.4 bits (98), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 18/46 (39%), Positives = 29/46 (63%)
 Frame = +3

Query: 1475 GDGTHTVTYTPSQEGPYIVSVKYADEEIPRSPFKVKVLPTYDASKV 1520
            G G + + YT  Q+G Y++ V++ DE IP SPF V V+  + A+ +
Sbjct: 27   GSGQYNINYTVKQQGSYMLIVRWGDENIPGSPFAVDVI*DFPAAHL 164

 Score = 38.9 bits (89), Expect = 0.028,   Method: Compositional matrix adjust.
 Identities = 20/52 (38%), Positives = 32/52 (61%), Gaps = 1/52 (1%)
 Frame = +3

Query: 1670 GTYDIFYTAAKPGTYVIYVRFGGVDIPNSPFTV-MVSRVPSPEPALTSRSTS 1720
            G Y+I YT  + G+Y++ VR+G  +IP SPF V ++   P+    LT+ S +
Sbjct: 33   GQYNINYTVKQQGSYMLIVRWGDENIPGSPFAVDVI*DFPAAHLDLTNSSVA 188

 Score = 36.6 bits (83), Expect = 0.13,   Method: Compositional matrix adjust.
 Identities = 19/46 (41%), Positives = 27/46 (58%), Gaps = 5/46 (10%)
 Frame = +3

Query: 906 HTVKYTPTQQGNMQVLVTYGGDPIPKSPFTVGV-----AAPLDLSK 946
           + + YT  QQG+  ++V +G + IP SPF V V     AA LDL+ 
Sbjct: 39  YNINYTVKQQGSYMLIVRWGDENIPGSPFAVDVI*DFPAAHLDLTN 176

 Score = 34.7 bits (78), Expect = 0.51,   Method: Compositional matrix adjust.
 Identities = 15/45 (33%), Positives = 28/45 (62%)
 Frame = +3

Query: 2254 EITFDDHKNGSCGVSYIAQEPGNYEVSIKFNDEHIPDSPYLVPVI 2298
            E+T     +G   ++Y  ++ G+Y + +++ DE+IP SP+ V VI
Sbjct: 6    ELTVKYVGSGQYNINYTVKQQGSYMLIVRWGDENIPGSPFAVDVI 140

 Score = 32.7 bits (73), Expect = 2.0,   Method: Compositional matrix adjust.
 Identities = 12/35 (34%), Positives = 20/35 (57%)
 Frame = +3

Query: 1883 GTCTVTYLPTLPGDYSILVKYNDKHIPGSPFTAKI 1917
            G   + Y     G Y ++V++ D++IPGSPF   +
Sbjct: 33   GQYNINYTVKQQGSYMLIVRWGDENIPGSPFAVDV 137

 Score = 32.7 bits (73), Expect = 2.1,   Method: Compositional matrix adjust.
 Identities = 15/35 (42%), Positives = 18/35 (51%)
 Frame = +3

Query: 509 GVYSFEYYPSTPGKYSVAVTWGGHHIPKSPFEVQV 543
           G Y+  Y     G Y + V WG  +IP SPF V V
Sbjct: 33  GQYNINYTVKQQGSYMLIVRWGDENIPGSPFAVDV 137

 Score = 32.0 bits (71), Expect = 3.2,   Method: Compositional matrix adjust.
 Identities = 12/35 (34%), Positives = 21/35 (60%)
 Frame = +3

Query: 2072 GTCKVSYFPTVPGVYIVSTKFADEHVPGSPFTVKI 2106
            G   ++Y     G Y++  ++ DE++PGSPF V +
Sbjct: 33   GQYNINYTVKQQGSYMLIVRWGDENIPGSPFAVDV 137

 Score = 31.6 bits (70), Expect = 4.5,   Method: Compositional matrix adjust.
 Identities = 13/33 (39%), Positives = 20/33 (60%)
 Frame = +3

Query: 1574 GTYAVTYIPDKTGRYMIGVTYGGDNIPLSPYRI 1606
            G Y + Y   + G YM+ V +G +NIP SP+ +
Sbjct: 33   GQYNINYTVKQQGSYMLIVRWGDENIPGSPFAV 131

 Score = 30.8 bits (68), Expect = 6.8,   Method: Compositional matrix adjust.
 Identities = 12/37 (32%), Positives = 22/37 (59%)
 Frame = +3

Query: 1091 GDGTCSVSYLPTKPGEYFVNILFEEVHIPGSPFKADI 1127
            G G  +++Y   + G Y + + + + +IPGSPF  D+
Sbjct: 27   GSGQYNINYTVKQQGSYMLIVRWGDENIPGSPFAVDV 137
>09100
          Length = 930

 Score = 53.1 bits (126), Expect = 1e-06,   Method: Composition-based stats.
 Identities = 35/119 (29%), Positives = 62/119 (52%), Gaps = 7/119 (5%)
 Frame = +1

Query: 10  EDAPWKKIQQ--NTFTRWCNEHLKCVNKRIG-----NLQTDLSDGLRLIALLEVLSQKRM 62
           E   W + QQ  + +  W N  LK   K+ G     +L+ D+ DG+    ++ ++S++++
Sbjct: 433 ESRTWIEPQQQLSAYMAWINSQLK---KKPGAHLIEDLRHDMRDGVVFADVIHIVSKQQI 603

Query: 63  HHKYHQRPTFRQMKLENVSVALEFLDHESIKLVSIDSKAIVDGNLKLILGLVWTLILHY 121
               +   T  +M+ +NV   L F+    IK+  I S+ IV+GNLK ++ L+  L  HY
Sbjct: 604 PGIQNVPTTLDEMR-QNVDRVLHFMTQNRIKMHRISSRDIVEGNLKAVMRLILALAAHY 777
>17613
          Length = 1108

 Score = 52.8 bits (125), Expect = 2e-06,   Method: Composition-based stats.
 Identities = 26/63 (41%), Positives = 40/63 (63%)
 Frame = +2

Query: 90  ESIKLVSIDSKAIVDGNLKLILGLVWTLILHYSISMPVWEDEGDDDAKKQTPKQRLLGWI 149
           + +KLVSI ++ IVDGN+K+ LG++WT+IL ++I         D   ++ T K+ LL W 
Sbjct: 59  KGVKLVSIGAEEIVDGNVKMTLGMIWTIILRFAIQ--------DITVEELTAKEGLLLWC 214

Query: 150 QNK 152
           Q K
Sbjct: 215 QRK 223
>35059
          Length = 669

 Score = 49.7 bits (117), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 43/178 (24%), Positives = 74/178 (41%), Gaps = 5/178 (2%)
 Frame = +2

Query: 2027 QGLSEGRTFEMSDFIVDTRDAGYGGISLAVEGPS-KVDIQTEDLEDGTCKVSYFPTVPGV 2085
            +G    R    ++F+VD R AG G + + ++G    + +    ++    + +Y P  PG 
Sbjct: 104  KGAEIARATVQAEFVVDGRRAGPGEVRVELKGVRISLPVHITPIKYDRYRCTYTPAFPGG 283

Query: 2086 YIVSTKFADEHVPGSPFTVKISGEGRVRESITRTSRAPAVATVGS----ICDLNLKIPEI 2141
            +++   +++  VPG P  V ++ +G V   +  T         GS      D        
Sbjct: 284  FLLYVYWSNILVPGCPHKVTVTSKGDV-SXVKVTGEGLKGGIAGSELRVFVDNKRGWSRG 460

Query: 2142 NSSDMSAHVTSPSGHVTEAEIVPMGKNSHCVRFVPQEMGVHTVSVKYRGQHVTGSPFQ 2199
             +SDM    T  +       + P+    H V   P     H + V+Y GQHV GSP +
Sbjct: 461  GNSDMFDTPTRGTSGREAERLSPL----HAVYPCPTSADKHLLQVRYDGQHVPGSPLR 622

 Score = 48.5 bits (114), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 36/125 (28%), Positives = 53/125 (42%), Gaps = 2/125 (1%)
 Frame = +2

Query: 1290 YQVEYTPFEKGFHVVEVTYDDVPIPNSPFKVAVTEGCQPSRVHAQGPGLKEAFT-NKSNV 1348
            Y+  YTP   G  ++ V + ++ +P  P KV VT     S V   G GLK     ++  V
Sbjct: 248  YRCTYTPAFPGGFLLYVYWSNILVPGCPHKVTVTSKGDVSXVKVTGEGLKGGIAGSELRV 427

Query: 1349 FTVVTRGAGIGGLGITVEGPSESKINCRDNKDGSCSAEY-IPFAPGDYDVNITYGGVHIP 1407
            F    RG   GG     + P+         +     A Y  P +   + + + Y G H+P
Sbjct: 428  FVDNKRGWSRGGNSDMFDTPTRGTSGREAERLSPLHAVYPCPTSADKHLLQVRYDGQHVP 607

Query: 1408 GSPFR 1412
            GSP R
Sbjct: 608  GSPLR 622

 Score = 46.2 bits (108), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 38/115 (33%), Positives = 54/115 (46%), Gaps = 3/115 (2%)
 Frame = +2

Query: 463 QPKGVRI-RET--ADFKVDTKAAGSGELGVTVKGPKGLEELVKQKGFLDGVYSFEYYPST 519
           Q KG  I R T  A+F VD + AG GE+ V +KG + +   V         Y   Y P+ 
Sbjct: 98  QVKGAEIARATVQAEFVVDGRRAGPGEVRVELKGVR-ISLPVHITPIKYDRYRCTYTPAF 274

Query: 520 PGKYSVAVTWGGHHIPKSPFEVQVGPEAGMQKVRAWGPGLHGGIVGRSADFVVES 574
           PG + + V W    +P  P +V V  +  +  V+  G GL GGI G      V++
Sbjct: 275 PGGFLLYVYWSNILVPGCPHKVTVTSKGDVSXVKVTGEGLKGGIAGSELRVFVDN 439

 Score = 45.8 bits (107), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 54/208 (25%), Positives = 78/208 (37%), Gaps = 2/208 (0%)
 Frame = +2

Query: 1128 EMPFDPSKVVASGPGLEHGKVGEPGILCVDCSEAGPGTLGLEAVSDSGAKAEVSIQNNKD 1187
              P+ P++      G E  +        VD   AGPG + +E +        V I   K 
Sbjct: 65   RFPWTPARSC*QVKGAEIARATVQAEFVVDGRRAGPGEVRVE-LKGVRISLPVHITPIKY 241

Query: 1188 GTYAVTYVPLTAGMYTLTMKYGGELVPHFPAWVKVEPAIDTSGIKAFGPGIEGKDVFREA 1247
              Y  TY P   G + L + +   LVP  P  V V    D S +K  G G++G     E 
Sbjct: 242  DRYRCTYTPAFPGGFLLYVYWSNILVPGCPHKVTVTSKGDVSXVKVTGEGLKGGIAGSEL 421

Query: 1248 TTDFTVDSRPLTQVGG-DHIKAQITNPSGASTECFVKDNADGTYQVEYTPFEKGFHVVEV 1306
               F  + R  ++ G  D         SG   E     +A     V   P     H+++V
Sbjct: 422  RV-FVDNKRGWSRGGNSDMFDTPTRGTSGREAERLSPLHA-----VYPCPTSADKHLLQV 583

Query: 1307 TYDDVPIPNSPFKVAVTEGCQ-PSRVHA 1333
             YD   +P SP +   +E  Q P+R   
Sbjct: 584  RYDGQHVPGSPLRP*ESESLQMPARCRC 667

 Score = 45.4 bits (106), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 50/215 (23%), Positives = 81/215 (37%), Gaps = 9/215 (4%)
 Frame = +2

Query: 2410 GLETGTTGIQSEFFINTTQAGPGTLSVTIEGPSKVKMDCQEIP---EGYKVMYTPMAPGN 2466
            G E     +Q+EF ++  +AGPG + V ++G  ++ +     P   + Y+  YTP  PG 
Sbjct: 107  GAEIARATVQAEFVVDGRRAGPGEVRVELKG-VRISLPVHITPIKYDRYRCTYTPAFPGG 283

Query: 2467 YLIGVKYGGPNHISRSPFKAKVTGQRLVSPGSANETSSILVESVTRSSTETCYSAIPKSS 2526
            +L+ V +                             S+ILV       T T       S 
Sbjct: 284  FLLYVYW-----------------------------SNILVPGCPHKVTVT-------SK 355

Query: 2527 SDASKVTSKGAGLSKAFVGQKSSFLVD----CSKAGSNMLLIGVHGPTTPCEEVSMKHVG 2582
             D S V   G GL     G +    VD     S+ G++ +        TP    S +   
Sbjct: 356  GDVSXVKVTGEGLKGGIAGSELRVFVDNKRGWSRGGNSDMF------DTPTRGTSGREAE 517

Query: 2583 KQQ-YNVTYVVKERGD-YVLAVKWGEEHIPGSPFH 2615
            +    +  Y      D ++L V++  +H+PGSP  
Sbjct: 518  RLSPLHAVYPCPTSADKHLLQVRYDGQHVPGSPLR 622

 Score = 44.7 bits (104), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 39/171 (22%), Positives = 69/171 (40%)
 Frame = +2

Query: 666 AEFIVDPKDAGSAPLKILAQDGEGQPIDIQMKSRMDGTYACSYTPLKAIKHTIAVVWGGV 725
           AEF+VD + AG   +++  + G    + + +       Y C+YTP       + V W  +
Sbjct: 137 AEFVVDGRRAGPGEVRVELK-GVRISLPVHITPIKYDRYRCTYTPAFPGGFLLYVYWSNI 313

Query: 726 NIPHSPYRVNIGQGSHPQKVKVFGPGVERSGLKANEPTHFTVDCTEAGEGDVSVGIKCDA 785
            +P  P++V +        VKV G G+ + G+  +E   F  +      G  S       
Sbjct: 314 LVPGCPHKVTVTSKGDVSXVKVTGEGL-KGGIAGSELRVFVDNKRGWSRGGNSDMFDTPT 490

Query: 786 RVLSDDEEDVDFDIIHNANDTFTVKYVPPAPGRYTIKVLFASQEIPASPFR 836
           R  S  E +         +    V   P +  ++ ++V +  Q +P SP R
Sbjct: 491 RGTSGREAE-------RLSPLHAVYPCPTSADKHLLQVRYDGQHVPGSPLR 622

 Score = 42.4 bits (98), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 41/162 (25%), Positives = 73/162 (45%), Gaps = 5/162 (3%)
 Frame = +2

Query: 384 AGVGDIGIEVEDPQGKNSVEL--LVEDRGNQVYRCVYKPVQPGPHVVKVSFAGDAIPKSP 441
           AG G++ +E++  +    V +  +  DR    YRC Y P  PG  ++ V ++   +P  P
Sbjct: 164 AGPGEVRVELKGVRISLPVHITPIKYDR----YRCTYTPAFPGGFLLYVYWSNILVPGCP 331

Query: 442 FGVQIGEACNPNACRASGRGLQP--KGVRIRETADFKVDTKAAGSGELGVT-VKGPKGLE 498
             V +    + +  + +G GL+    G  +R   D K      G+ ++  T  +G  G E
Sbjct: 332 HKVTVTSKGDVSXVKVTGEGLKGGIAGSELRVFVDNKRGWSRGGNSDMFDTPTRGTSGRE 511

Query: 499 ELVKQKGFLDGVYSFEYYPSTPGKYSVAVTWGGHHIPKSPFE 540
              ++   L  VY     P++  K+ + V + G H+P SP  
Sbjct: 512 --AERLSPLHAVYPC---PTSADKHLLQVRYDGQHVPGSPLR 622

 Score = 41.6 bits (96), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 40/175 (22%), Positives = 73/175 (41%), Gaps = 4/175 (2%)
 Frame = +2

Query: 2219 GLERGEAGIPAEFSIWTREAGAGGLSIAVEGPSKA---EITFDDHKNGSCGVSYIAQEPG 2275
            G E   A + AEF +  R AG G + + ++G   +    IT   +    C  +Y    PG
Sbjct: 107  GAEIARATVQAEFVVDGRRAGPGEVRVELKGVRISLPVHITPIKYDRYRC--TYTPAFPG 280

Query: 2276 NYEVSIKFNDEHIPDSPYLVPVIAPSDDARCLTVLSLQESGLKVNQPASFAIRLNG-AKG 2334
             + + + +++  +P  P+ V V +  D +         + G+  ++   F     G ++G
Sbjct: 281  GFLLYVYWSNILVPGCPHKVTVTSKGDVSXVKVTGEGLKGGIAGSELRVFVDNKRGWSRG 460

Query: 2335 KIDAKVHSPSGAVEECHVSELEPDKYAVRFIPHENGIHTIDVKFNGSHVVGSPFK 2389
                   +P+          L P  +AV   P     H + V+++G HV GSP +
Sbjct: 461  GNSDMFDTPTRGTSGREAERLSP-LHAVYPCPTSADKHLLQVRYDGQHVPGSPLR 622

 Score = 41.6 bits (96), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 41/175 (23%), Positives = 74/175 (42%), Gaps = 7/175 (4%)
 Frame = +2

Query: 963  EFAIDTNGAG-GQGKLDVTILSPSRKVVPCLVAPVAGRECSTAKFIPREEGLFAVDVTYD 1021
            EF +D   AG G+ +++   L   R  +P  + P+   +     + P   G F + V + 
Sbjct: 140  EFVVDGRRAGPGEVRVE---LKGVRISLPVHITPIK-YDRYRCTYTPAFPGGFLLYVYWS 307

Query: 1022 GHPVPGSPYTVEASLPPDPTKVKAHGPGLEGGLVGKPAEFTIDTKXXXXXXXXXXV-EGP 1080
               VPG P+ V  +   D + VK  G GL+GG+ G      +D K          + + P
Sbjct: 308  NILVPGCPHKVTVTSKGDVSXVKVTGEGLKGGIAGSELRVFVDNKRGWSRGGNSDMFDTP 487

Query: 1081 CEAKI-ECSDNGDGTCSVSYLPTKPGEYFVNILFEEVHIPGSPFK----ADIEMP 1130
                    ++      +V   PT   ++ + + ++  H+PGSP +      ++MP
Sbjct: 488  TRGTSGREAERLSPLHAVYPCPTSADKHLLQVRYDGQHVPGSPLRP*ESESLQMP 652

 Score = 40.4 bits (93), Expect = 0.011,   Method: Compositional matrix adjust.
 Identities = 31/121 (25%), Positives = 55/121 (45%), Gaps = 1/121 (0%)
 Frame = +2

Query: 1098 SYLPTKPGEYFVNILFEEVHIPGSPFKADIEMPFDPSKVVASGPGLEHGKVGEPGILCVD 1157
            +Y P  PG + + + +  + +PG P K  +    D S V  +G GL+ G  G    + VD
Sbjct: 257  TYTPAFPGGFLLYVYWSNILVPGCPHKVTVTSKGDVSXVKVTGEGLKGGIAGSELRVFVD 436

Query: 1158 CSEAGPGTLGLEAVSDSGAKAEVSIQNNK-DGTYAVTYVPLTAGMYTLTMKYGGELVPHF 1216
             ++ G    G   + D+  +     +  +    +AV   P +A  + L ++Y G+ VP  
Sbjct: 437  -NKRGWSRGGNSDMFDTPTRGTSGREAERLSPLHAVYPCPTSADKHLLQVRYDGQHVPGS 613

Query: 1217 P 1217
            P
Sbjct: 614  P 616

 Score = 37.7 bits (86), Expect = 0.061,   Method: Compositional matrix adjust.
 Identities = 46/188 (24%), Positives = 72/188 (38%), Gaps = 1/188 (0%)
 Frame = +2

Query: 1636 FVVDAKTAGKGKVTCVILTPDGTEAEADVIENEDGTYDIFYTAAKPGTYVIYVRFGGVDI 1695
            FVVD + AG G+V  V L          +   +   Y   YT A PG +++YV +  + +
Sbjct: 143  FVVDGRRAGPGEVR-VELKGVRISLPVHITPIKYDRYRCTYTPAFPGGFLLYVYWSNILV 319

Query: 1696 PNSPFTVMVSRVPSPEPALTSRSTSTCWKL-GEGRAQAVGSWVTEEAYVPVSDMNGLGFK 1754
            P  P  V V          TS+   +  K+ GEG    +      E  V V +  G    
Sbjct: 320  PGCPHKVTV----------TSKGDVSXVKVTGEGLKGGIAG---SELRVFVDNKRGWS-- 454

Query: 1755 PFDLVIPFAVRKGEITGTVHMPSGKKATPEIVDNKDGTVTVRYAPTEVGLHEMHIKYRGS 1814
                       +G  +     P+   +  E  +       V   PT    H + ++Y G 
Sbjct: 455  -----------RGGNSDMFDTPTRGTSGRE-AERLSPLHAVYPCPTSADKHLLQVRYDGQ 598

Query: 1815 HIPGNPLQ 1822
            H+PG+PL+
Sbjct: 599  HVPGSPLR 622

 Score = 36.2 bits (82), Expect = 0.19,   Method: Compositional matrix adjust.
 Identities = 43/196 (21%), Positives = 71/196 (36%), Gaps = 15/196 (7%)
 Frame = +2

Query: 1328 PSRVHAQGPGLKEAFTNKSNVFTVVTRGAGIGGLGITVEGPSES-KINCRDNKDGSCSAE 1386
            P+R   Q  G + A       F V  R AG G + + ++G   S  ++    K       
Sbjct: 80   PARSC*QVKGAEIARATVQAEFVVDGRRAGPGEVRVELKGVRISLPVHITPIKYDRYRCT 259

Query: 1387 YIPFAPGDYDVNITYGGVHIPGSPFRVPSKDVVDPSKVKIAGPGLSSCVRACIPQSFT-- 1444
            Y P  PG + + + +  + +PG P +V      D S VK+ G GL   +     + F   
Sbjct: 260  YTPAFPGGFLLYVYWSNILVPGCPHKVTVTSKGDVSXVKVTGEGLKGGIAGSELRVFVDN 439

Query: 1445 ------------VDSSKAGLAPLEVRVLGPRGLVEPVNVVDNGDGTHTVTYTPSQEGPYI 1492
                         D+   G +  E   L P                H V   P+    ++
Sbjct: 440  KRGWSRGGNSDMFDTPTRGTSGREAERLSP---------------LHAVYPCPTSADKHL 574

Query: 1493 VSVKYADEEIPRSPFK 1508
            + V+Y  + +P SP +
Sbjct: 575  LQVRYDGQHVPGSPLR 622

 Score = 36.2 bits (82), Expect = 0.19,   Method: Compositional matrix adjust.
 Identities = 26/86 (30%), Positives = 43/86 (50%), Gaps = 2/86 (2%)
 Frame = +2

Query: 2535 KGAGLSKAFVGQKSSFLVDCSKAGSNMLLIGVHGP--TTPCEEVSMKHVGKQQYNVTYVV 2592
            KGA +++A V  ++ F+VD  +AG   + + + G   + P     +K+    +Y  TY  
Sbjct: 104  KGAEIARATV--QAEFVVDGRRAGPGEVRVELKGVRISLPVHITPIKY---DRYRCTYTP 268

Query: 2593 KERGDYVLAVKWGEEHIPGSPFHVTV 2618
               G ++L V W    +PG P  VTV
Sbjct: 269  AFPGGFLLYVYWSNILVPGCPHKVTV 346

 Score = 35.8 bits (81), Expect = 0.24,   Method: Compositional matrix adjust.
 Identities = 41/147 (27%), Positives = 51/147 (34%), Gaps = 18/147 (12%)
 Frame = +2

Query: 901  NYDYSHTVKYTPTQQGNMQVLVTYGGDPIPKSPFTVGVAAPLDLSKIK---------ING 951
             YD  +   YTP   G   + V +    +P  P  V V +  D+S +K         I G
Sbjct: 236  KYD-RYRCTYTPAFPGGFLLYVYWSNILVPGCPHKVTVTSKGDVSXVKVTGEGLKGGIAG 412

Query: 952  LENRVEV---------GKDQEFAIDTNGAGGQGKLDVTILSPSRKVVPCLVAPVAGRECS 1002
             E RV V         G    F   T G  G+   +   LSP   V PC           
Sbjct: 413  SELRVFVDNKRGWSRGGNSDMFDTPTRGTSGR---EAERLSPLHAVYPC----------- 550

Query: 1003 TAKFIPREEGLFAVDVTYDGHPVPGSP 1029
                 P       + V YDG  VPGSP
Sbjct: 551  -----PTSADKHLLQVRYDGQHVPGSP 616
>09711
          Length = 3041

 Score = 47.8 bits (112), Expect = 6e-05,   Method: Compositional matrix adjust.
 Identities = 56/218 (25%), Positives = 102/218 (46%), Gaps = 14/218 (6%)
 Frame = +1

Query: 18   QQNTFTRWCNEHLKCVNKRIGNLQTDLSDGLRLIALLEV----LSQKRMHHKYHQRPTFR 73
            ++ T+  W N     V+  + +L +DL DGL +  L +     L       K   +   R
Sbjct: 850  EEKTYRNWMNS--LGVSPFVHHLYSDLYDGLIIFQLYDYIQPGLVDWSKVKKKFNKLKAR 1023

Query: 74   QMKLENVSVALEF---LDHESIKLVSIDSKAIVDGNLKLILGLVWTLILHYSISMPVWED 130
              ++EN + A+E    +    +KLV I  + I+DGN  L LGLVW L+  Y++++     
Sbjct: 1024 FERIENCNYAVELGPQVKLVKVKLVGIAGQDILDGNPVLTLGLVWQLMRAYTLAILSKIT 1203

Query: 131  EGDDDAKKQTPKQRLLGWIQNKIPYLP-ITNF-NQNWQDGKALGALVDSCAPGLCPDWES 188
            E +    K      ++ W+ +KI     I+ F ++   DG  +  ++++  PG+  +W++
Sbjct: 1204 ENN----KPISDNEIITWVNSKIKKDDRISGFQDRKLNDGVIVARVIEAIKPGIV-NWDN 1368

Query: 189  WDP-----RKPVDNAREAMQQADDWLGVPQVITPEEII 221
             D      +  + NAR A+  A   +G      PE+I+
Sbjct: 1369 IDCSARDYQDRLTNARYAIGLARK-IGAGVYALPEDIV 1479

 Score = 38.9 bits (89), Expect = 0.026,   Method: Compositional matrix adjust.
 Identities = 45/192 (23%), Positives = 79/192 (41%), Gaps = 29/192 (15%)
 Frame = +1

Query: 18  QQNTFTRWCNEHLKCVNKRIGNLQTDLSDGLRLIALLE--VLSQKRMHHKYHQRPTFRQM 75
           +Q  F  W N HL         L  D +DG +L   +   VL  K ++H        R +
Sbjct: 52  EQKAFAEWINRHLSDXPDCKHLLPLD-ADGTQLFGQMADGVLLCKLINHSVSNTIDERTI 228

Query: 76  KLENVSVALEFLDHESIKL------------VSIDSKAIVDGNLKLILGLVWTLIL---- 119
             +N+S+   +  HE++ L            V+I  + +  G   L+LGL+W +I     
Sbjct: 229 NKQNLSL---YRRHENLTLAVNSAGAIGCTTVNIGPEDLAAGRPHLVLGLLWQIIRIGLL 399

Query: 120 -------HYSISMPVWEDEGDDDAKKQTPKQRLLGWIQNKIPYL----PITNFNQNWQDG 168
                  H  +   + + E  +D  + +P+Q LL W+   +        I NF ++ +D 
Sbjct: 400 SDINLAHHPGLVNLLLDGETIEDLIRLSPEQILLRWVNYHLNRAGCDRQIXNFGEDIKDS 579

Query: 169 KALGALVDSCAP 180
           +A   L+   +P
Sbjct: 580 EAYTHLLKQISP 615
>04951
          Length = 2852

 Score = 46.2 bits (108), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 48/159 (30%), Positives = 79/159 (49%), Gaps = 12/159 (7%)
 Frame = +1

Query: 76  KLENVSVALEF---LDHESIKLVSIDSKAIVDGNLKLILGLVWTLILHYSISM--PVWED 130
           K+EN   A++    +    +KLV I  K I DGN  L LGLVW L+  Y++++   + ED
Sbjct: 4   KIENCEYAVQLGPQMKVCKMKLVGIGGKDIHDGNPVLTLGLVWQLMRAYTLAILSKLTED 183

Query: 131 EGDDDAKKQTPKQRLLGWIQNKIPY-LPITNF-NQNWQDGKALGALVDSCAPGLCPDWES 188
                 KK      ++ W+ +K+     I +F +    DG  +  +++S  PG+  +WE+
Sbjct: 184 ------KKPIQDSEIVDWVNSKVKKDERIGSFQDSKLNDGVIVAKVIESIKPGIV-NWEN 342

Query: 189 WDPR--KPVD---NAREAMQQADDWLGVPQVITPEEIIH 222
            +P   +P D   NAR A+  A   +G      PE+I+ 
Sbjct: 343 INPNASEPDDRLANARYAIGLARK-IGAGVYALPEDIVE 456
>18202
          Length = 424

 Score = 40.8 bits (94), Expect = 0.007,   Method: Composition-based stats.
 Identities = 35/135 (25%), Positives = 67/135 (49%), Gaps = 3/135 (2%)
 Frame = -1

Query: 22  FTRWCNEHLKCVNKRIGNLQTDLSDGLRLIALLEVLS-QKRMHHKYHQRPTFRQMKLENV 80
           +  W N  L  VN  + N+ + + +G  L  L++VL+ +  +  K        Q     +
Sbjct: 379 YLSWANSVLCEVNSSVENVSS-IQEGRVLCELIDVLAPEAGLLDKVQASGKSGQRAF--I 209

Query: 81  SVALEFLDHESIKLVSIDSKAIVDGNLKLILGLVWTLILHYSISMPVWEDEGDDDAKKQ- 139
             AL+ + +  IK+V   ++ I+DG++K +L ++W LIL+Y I        G++  ++  
Sbjct: 208 YAALDHMKNHGIKIV-FSTQDIMDGDIKSLLDVMWLLILNYGIHFI-----GNNSFQRSV 47

Query: 140 -TPKQRLLGWIQNKI 153
              K+ LL W Q ++
Sbjct: 46  GAGKKNLLDWCQGEL 2
>32088
          Length = 1928

 Score = 37.4 bits (85), Expect = 0.091,   Method: Composition-based stats.
 Identities = 36/156 (23%), Positives = 64/156 (41%), Gaps = 21/156 (13%)
 Frame = +1

Query: 15   KKIQQNTFTRWCNEHLK----C-----VNKRIGNLQTDLSDGLRLIALLEVLSQKRMHHK 65
            K  +Q  F  W N HLK    C     VN+   +L   + DG+ L  L+       +  +
Sbjct: 1255 KDGEQKAFAAWINRHLKDDPDCKHLMEVNEEGDDLFKKVGDGILLCKLINHSVSNTIDER 1434

Query: 66   YHQRPTFR-QMKLENVSVALEFLDHESIKLVSIDSKAIVDGNLKLILGLVWTLIL----- 119
               +       + EN+++A+          V+I  + +  G   L+LGL+W +I      
Sbjct: 1435 AINKSNLNVYHRHENLTLAVNSAGSIGCTTVNIGPEDLAAGRPHLVLGLLWQIIRIGLLS 1614

Query: 120  ------HYSISMPVWEDEGDDDAKKQTPKQRLLGWI 149
                  H  +   + E E  +D  + +P++ LL W+
Sbjct: 1615 DINLAHHPGLVNLLREGETIEDFMRLSPEEILLRWV 1722
>31031
          Length = 423

 Score = 35.0 bits (79), Expect = 0.35,   Method: Compositional matrix adjust.
 Identities = 25/99 (25%), Positives = 41/99 (41%), Gaps = 13/99 (13%)
 Frame = +1

Query: 1831 GSVSAYGPGLVYGVANKTATFTI---------VTEDAGEGGLDLAIEGPS---KAEISCI 1878
            G  S +GPGL          F I         +T+  GEG   +++       +  +  +
Sbjct: 4    GGYSGWGPGLKSHFNVPVRYFYIQAVDTKGNHLTDSVGEGAFQVSVTQNGQRVRMRVDVL 183

Query: 1879 DNKDGTCTVTYLP-TLPGDYSILVKYNDKHIPGSPFTAK 1916
            D  DG   V   P + P    + +K+ND+H+  SP+  K
Sbjct: 184  DRHDGVYIVRLKPFSDPEHIVVSIKHNDQHVAHSPYQIK 300
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6755100|ref|NP_035249.1| ErbB3-binding protein 1 [Mus
musculus]
         (394 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

05442                                                                 395   e-114
15458                                                                  82   8e-30
25432                                                                  35   0.035
23585                                                                  33   0.29 
20404                                                                  32   0.30 
00491                                                                  30   1.2  
02696                                                                  30   1.3  
26885                                                                  30   1.6  
>05442
          Length = 1171

 Score =  395 bits (1016), Expect(2) = e-114,   Method: Compositional matrix adjust.
 Identities = 177/284 (62%), Positives = 230/284 (80%)
 Frame = +1

Query: 75  AFPTSISVNNCVCHFSPLKSDQDYILKEGDLVKIDLGVHVDGFIANVAHTFVIGVAQGTQ 134
           AFPT +S+NNC+CHFSPLKSD D  LK+GD+VKIDLG HVDG+I   AHT V+G ++  +
Sbjct: 133 AFPTCVSINNCICHFSPLKSDPDITLKDGDMVKIDLGAHVDGYIGVAAHTLVVGASKDKK 312

Query: 135 VTGRKADVIKAAHLCAEAALRLVKPGNQNTQVTEAWNKVAHSFNCTPIEGMLSHQLKQHV 194
           V+GRKADV+ AAH+  EAALR+VKPGN+N QVT+   KVA ++NC P+EGMLSHQL + V
Sbjct: 313 VSGRKADVMTAAHMAVEAALRMVKPGNENDQVTDCIQKVAEAYNCKPVEGMLSHQLLKDV 492

Query: 195 IDGEKTIIQNPTDQQKKDHEKAEFEVHEVYAVDVLVSSGEGKAKDAGQRTTIYKRDPSKQ 254
           IDG+K  IQNP++ Q+KDH+K EFEVHEVYA+DV++S+GEGK ++   RTT+YK+     
Sbjct: 493 IDGDKAFIQNPSEAQRKDHDKCEFEVHEVYAIDVIISTGEGKGRELDTRTTVYKKR-DMV 669

Query: 255 YGLKMKTSRAFFSEVERRFDAMPFTLRAFEDEKKARMGVVECAKHELLQPFNVLYEKEGE 314
           Y LKMK SR F SE +++F  MPF+LR  EDEKKA+MGVVEC KH L+QPF VL+++EGE
Sbjct: 670 YQLKMKASRQFLSETDKKFGLMPFSLRLLEDEKKAKMGVVECVKHGLMQPFGVLFDREGE 849

Query: 315 FVAQFKFTVLLMPNGPMRITSGPFEPDLYKSEMEVQDAELKALL 358
            VAQFK TV+LMPNGP++IT  PF+ +LY+S+++V+D E+KALL
Sbjct: 850 VVAQFKTTVILMPNGPLKITGLPFQSELYQSDLKVEDEEVKALL 981

 Score = 33.9 bits (76), Expect(2) = e-114,   Method: Compositional matrix adjust.
 Identities = 14/30 (46%), Positives = 21/30 (70%)
 Frame = +2

Query: 31 VLRSLVEASSSGVSVLSLCEKGDAMIMEET 60
          +L+ L+    +G SVL LCE GD+ ++EET
Sbjct: 2  ILKELIGKCEAGASVLGLCELGDSRLLEET 91
>15458
          Length = 965

 Score = 81.6 bits (200), Expect(2) = 8e-30,   Method: Compositional matrix adjust.
 Identities = 43/109 (39%), Positives = 62/109 (56%), Gaps = 1/109 (0%)
 Frame = -3

Query: 174 AHSFNCTPIEGMLSHQLKQHVIDGEKTIIQNPTDQQKKDHEKAEFEVHEVYAVDVLVSSG 233
           A + NC P+EGMLSHQL + VIDG+K  IQNP++ Q++       +  +   + +L    
Sbjct: 549 AAALNCKPVEGMLSHQLLKDVIDGDKAFIQNPSEAQRRIMTNVNLKFTKFTPLTLLSVLE 370

Query: 234 EGKAKDAGQRT-TIYKRDPSKQYGLKMKTSRAFFSEVERRFDAMPFTLR 281
             + ++  Q      KRD    Y LKMK SR F SE +++F  MPF+LR
Sbjct: 369 RERVENWTQELQCTKKRDMV--YQLKMKASRQFLSETDKKFGLMPFSLR 229

 Score = 66.6 bits (161), Expect(2) = 8e-30,   Method: Compositional matrix adjust.
 Identities = 29/46 (63%), Positives = 40/46 (86%)
 Frame = -1

Query: 313 GEFVAQFKFTVLLMPNGPMRITSGPFEPDLYKSEMEVQDAELKALL 358
           GE VAQFK TV+LMPNGP++IT  PF+ +LY+S+++V+D E+KALL
Sbjct: 230 GEVVAQFKTTVILMPNGPLKITGLPFQSELYQSDLKVEDEEVKALL 93
>25432
          Length = 557

 Score = 35.4 bits (80), Expect = 0.035,   Method: Compositional matrix adjust.
 Identities = 29/133 (21%), Positives = 54/133 (40%), Gaps = 2/133 (1%)
 Frame = -3

Query: 154 LRLVKPGNQNTQVTEAWNKV--AHSFNCTPIEGMLSHQLKQHVIDGEKTIIQNPTDQQKK 211
           +RL   G +  +V E++       ++   PI  +  H + Q+ I   KT+   P     K
Sbjct: 450 VRLCDVGERIQEVMESYEVELDGKTYQVKPIRNLNGHSVGQYRIHAGKTV---PI---VK 289

Query: 212 DHEKAEFEVHEVYAVDVLVSSGEGKAKDAGQRTTIYKRDPSKQYGLKMKTSRAFFSEVER 271
             +    E  EVYA++   S+G+G   D  + +   K        L++  S+   + +  
Sbjct: 288 GGDATRMEEGEVYAIETFGSTGKGVVHDDMETSHYMKNFEVGHVPLRLAKSKQLLNVINN 109

Query: 272 RFDAMPFTLRAFE 284
            F  + F  R  +
Sbjct: 108 NFSTLAFCRRWLD 70
>23585
          Length = 1625

 Score = 32.7 bits (73), Expect = 0.29,   Method: Compositional matrix adjust.
 Identities = 21/57 (36%), Positives = 26/57 (45%)
 Frame = -3

Query: 136  TGRKADVIKAAHLCAEAALRLVKPGNQNTQVTEAWNKVAHSFNCTPIEGMLSHQLKQ 192
             GRK D +    LC    +RLVKPG     VT    +V H  NC+   G L   + Q
Sbjct: 1218 NGRKPDPV----LCPARMIRLVKPGGYIVNVT----RVEHLNNCSDYIGRLEQLMDQ 1072
>20404
          Length = 396

 Score = 32.3 bits (72), Expect = 0.30,   Method: Compositional matrix adjust.
 Identities = 15/40 (37%), Positives = 23/40 (57%)
 Frame = +1

Query: 115 DGFIANVAHTFVIGVAQGTQVTGRKADVIKAAHLCAEAAL 154
           D  +  V++   IG++QG  +T  KA +IK   LC+ A L
Sbjct: 271 DLLLYRVSNFLWIGISQGLALTLAKATLIKLKSLCSPALL 390
>00491
          Length = 1057

 Score = 30.4 bits (67), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 11/34 (32%), Positives = 20/34 (58%)
 Frame = -2

Query: 163 NTQVTEAWNKVAHSFNCTPIEGMLSHQLKQHVID 196
           NTQ+   ++K+ H +NC P   +  H+L  ++I 
Sbjct: 978 NTQLMVIFHKIMHMYNCKPYPVIKKHKLYAYMIS 877
>02696
          Length = 1092

 Score = 30.4 bits (67), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 18/57 (31%), Positives = 36/57 (63%)
 Frame = -2

Query: 186  LSHQLKQHVIDGEKTIIQNPTDQQKKDHEKAEFEVHEVYAVDVLVSSGEGKAKDAGQ 242
            + ++L+QH+  GEK II+  T++Q K++ K ++    +Y + +   S E  +++AGQ
Sbjct: 1034 ICNRLEQHISIGEKIIIRT*TNKQNKNNFKVQY--M*LYHIKL---SNEASSQEAGQ 879
>26885
          Length = 416

 Score = 30.0 bits (66), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 12/37 (32%), Positives = 16/37 (43%)
 Frame = -2

Query: 155 RLVKPGNQNTQVTEAWNKVAHSFNCTPIEGMLSHQLK 191
           R+  P   N      +N + H F C PIE    HQ +
Sbjct: 397 RVYGPPESNAITGIIYNALGHRFKCAPIERQTQHQFR 287
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|71725365|ref|NP_001025153.1| Sec23 interacting
protein [Mus musculus]
         (998 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

11319                                                                 336   e-114
11763                                                                 173   1e-84
11761                                                                 169   7e-42
14501                                                                 122   5e-28
10413                                                                  79   8e-15
12662                                                                  46   9e-05
13622                                                                  36   0.074
01467                                                                  35   0.15 
>11319
          Length = 1706

 Score =  336 bits (862), Expect(2) = e-114,   Method: Compositional matrix adjust.
 Identities = 163/350 (46%), Positives = 232/350 (66%), Gaps = 9/350 (2%)
 Frame = +3

Query: 352 IPYTEEFSEKLEAEYKKAVSTNQWHRRLEFPSGETIVMHNPKVIVQFQPSSVPDEWGTTQ 411
           +P+ E  ++ LEAEYK A   N WH+R+E P G+++VMH+  V V F  +S PDEWG  Q
Sbjct: 435 VPFDETVADSLEAEYKNATEHNDWHKRIELPRGDSVVMHSSTVFVHFHAASQPDEWGNVQ 614

Query: 412 DGQTRPRVVKRGIDDSLDEIPDGEMPQVDHLVFMVHGIGPVCDLRFRSIIECVDDFRVVS 471
             Q RPRVVKRG+DD    +  GE  +VDHL+F++HGIG  CD++FR+I++CVDDFR +S
Sbjct: 615 SDQ-RPRVVKRGVDD-FGTVESGESEEVDHLIFVLHGIGETCDVQFRNIVDCVDDFRSIS 788

Query: 472 LKLLQTHFKKSVDEGKVSRVEFLPVHWHSALGGHATGVDRNIKKITLPSIGRFRHFTNET 531
            +L+ +HF    + G V RVE+LPV WH+A+    TGVD+ +K ITLPS  + R F N T
Sbjct: 789 NELITSHFGPYTESGHVHRVEYLPVQWHAAVHSDTTGVDKRLKAITLPSTQKLRDFVNNT 968

Query: 532 LLDVLFYNSPTYCQAIVEKVEVEINRLHSLFMSRNPNFKGKVSVAGHSLGSLILFDILSN 591
           L+D+LFY SP YCQ I +KV  E+NRL  LF++RNP F G+VSVAGHSLGS ILFD+L +
Sbjct: 969 LMDILFYTSPAYCQTICDKVCQEMNRLFQLFLARNPLFSGEVSVAGHSLGSSILFDLLLH 1148

Query: 592 QRDMCVSKSPGSVAVSNGVIKHSQFQEKLISEESKLMSDESC------DLDVEDEE---P 642
           Q +   +    +   S   +K+S   ++ ++ +SK  S E         +D E  E    
Sbjct: 1149QEEARDAADSAAFNGSTDTLKNSTESQEQMATKSKQESAEQIVKFKKDSVDPEGLEVVPE 1328

Query: 643 LTLHGTLEALSLFDYISTFEKEKIDMESLLMCTVDDLKEMGIPLGPRKKI 692
           LTL   L+ + L D +  F++E+ID+++L MC+  DLK++G+P+GPR+K+
Sbjct: 1329LTLEQVLDKVGLKDKMPIFQQEQIDLDALTMCSEQDLKDLGLPMGPRRKL 1478

 Score = 94.0 bits (232), Expect(2) = e-114,   Method: Compositional matrix adjust.
 Identities = 44/89 (49%), Positives = 59/89 (66%)
 Frame = +2

Query: 262 YEPVQPHWFYCKEVEYKQLWMPFSVLDSLNLEEIYNSVQPDPESVVLGTDGGRYDVYLYD 321
           Y  V+ HW Y K VE +++W  FS LDS  LE+ Y   +    + V+ TDGGRYDV +  
Sbjct: 164 YHAVRHHWCYRKVVEGQEIWCTFSRLDSDKLEQQYLKERNGGAAAVVSTDGGRYDVEIGP 343

Query: 322 RMRKSVYWEEEPTEVRRCTWFYKGDTDSR 350
           R+R+SVYW EEP  ++RC+WFYK D D+R
Sbjct: 344 RLRRSVYWIEEPFPIQRCSWFYKRDRDNR 430
>11763
          Length = 894

 Score =  173 bits (439), Expect(2) = 1e-84,   Method: Composition-based stats.
 Identities = 79/150 (52%), Positives = 103/150 (68%)
 Frame = +1

Query: 292 LEEIYNSVQPDPESVVLGTDGGRYDVYLYDRMRKSVYWEEEPTEVRRCTWFYKGDTDSRF 351
           LEE +   Q      V+ TDGGRYDV +  R+R++VYWEEEP  ++RC+WF+K + D+R+
Sbjct: 7   LEEQFRKEQNGTAPEVVNTDGGRYDVEIQTRLRRAVYWEEEPGLIQRCSWFFKREADNRY 186

Query: 352 IPYTEEFSEKLEAEYKKAVSTNQWHRRLEFPSGETIVMHNPKVIVQFQPSSVPDEWGTTQ 411
           +PY E  + +LE EYK AV  N+WH+R+E    +TIVMHNP VIV F+ SS PDEWG  Q
Sbjct: 187 VPYEEAQAARLEVEYKNAVERNEWHKRIELAGQDTIVMHNPNVIVHFKASSQPDEWGNVQ 366

Query: 412 DGQTRPRVVKRGIDDSLDEIPDGEMPQVDH 441
             Q RPRVVKRG+DD    +  GE  +VDH
Sbjct: 367 GDQMRPRVVKRGVDD-FGTVEPGESVEVDH 453

 Score =  159 bits (403), Expect(2) = 1e-84,   Method: Composition-based stats.
 Identities = 72/134 (53%), Positives = 94/134 (70%), Gaps = 1/134 (0%)
 Frame = +2

Query: 442 LVFMVHGIGPVCDLRFRSIIECVDDFRVVSLKLLQTHFKKSVDEGKVSRVEFLPVHWHSA 501
           LVF++HGIG +CD+RFR+I+ECVDDFR ++  L+QTHF      G + RVEFLPVHWH A
Sbjct: 455 LVFVLHGIGDMCDVRFRNIVECVDDFRSIANGLIQTHFGPYSQGGHIHRVEFLPVHWHMA 634

Query: 502 LGGHATGVDRNIKKITLPSIGRFRHFTNETLLDVLFYNSPTYCQAIVEKVEVEINRLHSL 561
           +   ATGVD  +K ITLPS  + R F N+TL+D+LFY SP YCQ I + V  E+NRL  +
Sbjct: 635 VHSEATGVDSRLKSITLPSTRKLRDFVNDTLMDILFYTSPAYCQIICDTVGQELNRLFQI 814

Query: 562 F-MSRNPNFKGKVS 574
           F +  N   +G +S
Sbjct: 815 FWLETNLQRRGVIS 856
>11761
          Length = 434

 Score =  169 bits (427), Expect = 7e-42,   Method: Compositional matrix adjust.
 Identities = 83/140 (59%), Positives = 100/140 (71%), Gaps = 4/140 (2%)
 Frame = +2

Query: 385 ETIVMHNPKVIVQFQPSSVPDEWG----TTQDGQTRPRVVKRGIDDSLDEIPDGEMPQVD 440
           +TIVMHNP VIV F+ SS PDEWG    T Q  Q RPRVVKRG+DD    +  GE  +VD
Sbjct: 5   DTIVMHNPNVIVHFKASSQPDEWGNVQPTVQGDQMRPRVVKRGVDD-FGTVEPGESVEVD 181

Query: 441 HLVFMVHGIGPVCDLRFRSIIECVDDFRVVSLKLLQTHFKKSVDEGKVSRVEFLPVHWHS 500
           HLVF++HGIG +CD+RF +I+ECVDDFR ++  L+QTHF      G + RVEFLPVHWH 
Sbjct: 182 HLVFVLHGIGDMCDVRFHNIVECVDDFRSIANGLIQTHFGPYSQGGHIHRVEFLPVHWHM 361

Query: 501 ALGGHATGVDRNIKKITLPS 520
           A+   ATGVD  +K ITLPS
Sbjct: 362 AVHSEATGVDSRLKSITLPS 421
>14501
          Length = 413

 Score =  122 bits (307), Expect = 5e-28,   Method: Compositional matrix adjust.
 Identities = 54/90 (60%), Positives = 67/90 (74%)
 Frame = +3

Query: 492 EFLPVHWHSALGGHATGVDRNIKKITLPSIGRFRHFTNETLLDVLFYNSPTYCQAIVEKV 551
           E+LPV WH+A+    TGVD+ +K ITLPS  + R F N TL+D+LFY SP YCQ I +KV
Sbjct: 3   EYLPVQWHAAVHSDTTGVDKRLKAITLPSTQKLRDFVNNTLMDILFYTSPAYCQTICDKV 182

Query: 552 EVEINRLHSLFMSRNPNFKGKVSVAGHSLG 581
             E+NRL  LF++RNP F G+VSVAGHSLG
Sbjct: 183 CQEMNRLFQLFLARNPLFSGEVSVAGHSLG 272
>10413
          Length = 578

 Score = 79.3 bits (194), Expect = 8e-15,   Method: Composition-based stats.
 Identities = 34/57 (59%), Positives = 44/57 (77%)
 Frame = +1

Query: 536 LFYNSPTYCQAIVEKVEVEINRLHSLFMSRNPNFKGKVSVAGHSLGSLILFDILSNQ 592
           LFY SP YCQ I + V  E+NRL  +F++RNP F G+VS+AGHSLG+ ILFD+L +Q
Sbjct: 1   LFYTSPAYCQIICDTVGQELNRLFQIFLARNPTFNGEVSLAGHSLGASILFDLLMHQ 171

 Score = 54.7 bits (130), Expect = 2e-07,   Method: Composition-based stats.
 Identities = 23/46 (50%), Positives = 35/46 (76%)
 Frame = +2

Query: 647 GTLEALSLFDYISTFEKEKIDMESLLMCTVDDLKEMGIPLGPRKKI 692
           G L  + L D +  F++E+ID+ESL MC+  DLK++G+P+GPRKK+
Sbjct: 335 GLLGKVGLKDKMDVFQQEQIDLESLSMCSEQDLKDLGLPMGPRKKL 472
>12662
          Length = 771

 Score = 45.8 bits (107), Expect = 9e-05,   Method: Compositional matrix adjust.
 Identities = 44/158 (27%), Positives = 73/158 (46%), Gaps = 3/158 (1%)
 Frame = -1

Query: 538 YNSPTYCQAIVEKVEVEINRLHSLFMSRNPNFKGKVSVAGHSLGSLILFDILSNQRDMCV 597
           +N P + +         +N L S  +  +P+  GK+S+ G+S              +   
Sbjct: 648 FNRPGFGKTAFLTGSSFLNTLPSFEVDGDPD--GKLSMNGYS-----------THVNGTE 508

Query: 598 SKSPGSVAVSNGVIKHSQFQEKLISEESKLMSDESCDLDVEDEEPLT---LHGTLEALSL 654
             S GS   + G    S  +E    +      DE  +LD +DE+ +T   L   L +  L
Sbjct: 507 GTSEGSADKAAGDGSWSDAKELPWDQ------DEVDNLD-DDEDGMTSSALEMFLWSAGL 349

Query: 655 FDYISTFEKEKIDMESLLMCTVDDLKEMGIPLGPRKKI 692
             Y+  F +EK+DME L+  +  +LKE+G+P GPRK++
Sbjct: 348 EAYLHKFLQEKVDMELLVKMSDSELKEIGLPFGPRKRL 235
>13622
          Length = 1144

 Score = 36.2 bits (82), Expect = 0.074,   Method: Compositional matrix adjust.
 Identities = 17/42 (40%), Positives = 26/42 (61%), Gaps = 1/42 (2%)
 Frame = +1

Query: 652 LSLFDYISTFEKEKIDMESLLMCTVDDLKEMGI-PLGPRKKI 692
           L L  YI  F++++ID  + L    +DLKE+GI   G R+K+
Sbjct: 541 LGLGKYIDIFQQQEIDFSTFLTLNEEDLKELGIGTFGARRKM 666
>01467
          Length = 1335

 Score = 35.0 bits (79), Expect = 0.15,   Method: Compositional matrix adjust.
 Identities = 18/38 (47%), Positives = 25/38 (65%), Gaps = 1/38 (2%)
 Frame = -2

Query: 656  DYISTFEKEKIDMESLLMCTVDDLKEMGI-PLGPRKKI 692
            DYI  F + +I ME++L  +  DLK+MG+  LG RK I
Sbjct: 1334 DYIPVFLRHRITMETMLQLSDADLKQMGVYELGLRKAI 1221
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|7305031|ref|NP_038841.1| erythrocyte protein band
4.1-like 3 [Mus musculus]
         (929 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

00990                                                                 409   e-114
18811                                                                 193   2e-49
11374                                                                 188   8e-48
17332                                                                 142   7e-34
13951                                                                  67   4e-20
28244                                                                  78   1e-14
08363                                                                  68   1e-11
03469                                                                  67   3e-11
05888                                                                  56   5e-08
17536                                                                  35   0.13 
12494                                                                  29   8.2  
>00990
          Length = 3161

 Score =  409 bits (1050), Expect = e-114,   Method: Compositional matrix adjust.
 Identities = 201/377 (53%), Positives = 261/377 (69%), Gaps = 8/377 (2%)
 Frame = +3

Query: 116 KSMQCKVTLLDGSEYGCDVDKRSRGQVLFDKVCEHLNLLEKDYFGLTYRD---AENQKNW 172
           K    +V LLDG     ++D+ + G+ LFDKVC+HL+L+EKDYFGL + D   + + K W
Sbjct: 252 KGFNYEVVLLDGEHVNFELDRNAEGRELFDKVCQHLDLIEKDYFGLQFVDERISNHLKCW 431

Query: 173 LDPAKEIKKQIRSGAWHFSFNVKFYPPDPAQLSEDITRYYLCLQLRDDIVSGRLPCSFVT 232
           L P K I KQ + G W F F +KFYPPDP QL E +TR+ + LQ R DI+SG+LP +++T
Sbjct: 432 LSPDKRISKQKKGGPWLFDFALKFYPPDPTQLRESLTRWLVVLQTRRDILSGKLPATYLT 611

Query: 233 LALLGSYTVQSELGDYDPDEC-GNDYISEFRFAPNHTKELEDKVIELHKSHRGMTPAEAE 291
            A+LGSY VQ+++GDYDP+E  G +YI +  FAPN T +L +K++ELH+ H+G TP EAE
Sbjct: 612 QAMLGSYCVQADVGDYDPNEHRGVEYIRDTPFAPNQTIDLLEKIVELHRQHKGQTPDEAE 791

Query: 292 MHFLENAKKLSMYGVDLHHAKDSEGVEIMLGVCASGLLIYRDRLRINRFAWPKVLKISYK 351
            +FLENAKKL+MYGVDLH A+D   V+IMLGVCASGL +YR++LRI+RF WPK+LKISYK
Sbjct: 792 TNFLENAKKLAMYGVDLHAAQDVNNVDIMLGVCASGLQVYREKLRISRFVWPKILKISYK 971

Query: 352 RNNFYIKIRPGEFEQFESTIGFKLPNHRAAKRLWKVCVEHHTFFRLLLPEAPPKK--FLT 409
           R  FYIK+RP +    E++  FKL  HR AKRLWK+CVEHH FFRL   E       F  
Sbjct: 972 RRQFYIKVRPSDNSAMENSFCFKLATHRLAKRLWKICVEHHAFFRLREAEQSQNAAMFPR 1151

Query: 410 LGSKFRYSGRTQAQTRRASALIDRPAPYFERSSSKRYTMSRSLDGASVSE--NHEIYMKD 467
           LGSKFRYSGRT  QTR++S ++DRP PYFERS   R + +     +S+ E  N   Y KD
Sbjct: 1152LGSKFRYSGRTLYQTRQSSQILDRPNPYFERSQPARSSFAPPAKASSLDELSNRPDYWKD 1331

Query: 468 SVSAAEVGTGQYATTKG 484
                E G G+   ++G
Sbjct: 1332-----EEGDGKRRPSEG 1367

 Score = 43.5 bits (101), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 21/48 (43%), Positives = 32/48 (66%), Gaps = 2/48 (4%)
 Frame = +3

Query: 869  KGGISETRIEKRIVITG--DADIDHDQALAQAIKEAKEQHPDMSVTKV 914
            K GI  TR+E ++V++   D + D+D ALA AI+   E +PDMSV ++
Sbjct: 2145 KDGIQHTRVEHKVVLSSADDEEFDYDAALADAIRSVTEFNPDMSVERI 2288
>18811
          Length = 478

 Score =  193 bits (491), Expect = 2e-49,   Method: Compositional matrix adjust.
 Identities = 82/133 (61%), Positives = 108/133 (81%)
 Frame = -2

Query: 254 GNDYISEFRFAPNHTKELEDKVIELHKSHRGMTPAEAEMHFLENAKKLSMYGVDLHHAKD 313
           G DYI +  FAPN   EL +K++ELH+ H+G TP EAE+++LENAKKLSMYGVDLH A+D
Sbjct: 399 GADYIKDIPFAPNQAPELLEKIVELHRQHKGQTPDEAEVNYLENAKKLSMYGVDLHAAQD 220

Query: 314 SEGVEIMLGVCASGLLIYRDRLRINRFAWPKVLKISYKRNNFYIKIRPGEFEQFESTIGF 373
              V+IMLGVC+SGL +YRD+LRI+RF WPK++KISYKR +FY+K+RP + +  E+++ F
Sbjct: 219 VNNVDIMLGVCSSGLQVYRDKLRISRFVWPKIIKISYKRKHFYVKVRPADNKGLETSVSF 40

Query: 374 KLPNHRAAKRLWK 386
           +LP HR AKRLWK
Sbjct: 39  RLPTHRLAKRLWK 1
>11374
          Length = 800

 Score =  188 bits (478), Expect = 8e-48,   Method: Compositional matrix adjust.
 Identities = 96/172 (55%), Positives = 113/172 (65%), Gaps = 8/172 (4%)
 Frame = +3

Query: 308 LHHAKDSEGVEIMLGVCASGLLIYRDRLRINRFAWPKVLKISYKRNNFYIKIRPGEFEQF 367
           LH A+D   V+IMLGVCASGL +YR++LRI+RF WPK+LKISYKR  FYIK+RP +    
Sbjct: 3   LHAAQDVNNVDIMLGVCASGLQVYREKLRISRFVWPKILKISYKRRQFYIKVRPSDNSAM 182

Query: 368 ESTIGFKLPNHRAAKRLWKVCVEHHTFFRLLLPEAPPKK--FLTLGSKFRYSGRTQAQTR 425
           E++  FKL  HR AKRLWK+CVEHH FFRL   E       F  LGSKFRYSGRT  QTR
Sbjct: 183 ENSFCFKLATHRLAKRLWKICVEHHAFFRLREAEQSQNAAMFPRLGSKFRYSGRTLYQTR 362

Query: 426 RASALIDRPAPYFERSSSKRYTM------SRSLDGASVSENHEIYMKDSVSA 471
            +S  +DRP PYFERS   R T       SRS+D  +   N   Y KD + A
Sbjct: 363 HSSQTLDRPDPYFERSQPARNTYAAPSTRSRSVDELT---NRPDYWKDDLDA 509
>17332
          Length = 473

 Score =  142 bits (357), Expect = 7e-34,   Method: Composition-based stats.
 Identities = 74/157 (47%), Positives = 99/157 (63%), Gaps = 2/157 (1%)
 Frame = +2

Query: 126 DGSEYGCDVDKRSRGQVLFDKVCEHLNLLEKDYFGLTYRDAENQKNWLDPAKEIKKQIR- 184
           D S++   V    +G +L +KVCE LNL EKDYFGL + DA  Q +WLD  K +  Q++ 
Sbjct: 2   DDSDHQLQVKGNWKGILLQEKVCELLNLHEKDYFGLRFIDASGQTHWLDGNKSLSSQLKG 181

Query: 185 -SGAWHFSFNVKFYPPDPAQLSEDITRYYLCLQLRDDIVSGRLPCSFVTLALLGSYTVQS 243
                   F VKFY  DP +L E+ITRY   LQ++ DI+ GRLP +F   + L +Y VQS
Sbjct: 182 CQTPHKLYFGVKFYAADPCKLREEITRYLFFLQVKQDILQGRLPVTFDEASELCAYAVQS 361

Query: 244 ELGDYDPDECGNDYISEFRFAPNHTKELEDKVIELHK 280
           ELGD+DP +  + Y+SEF F PN T+ELE +V  LH+
Sbjct: 362 ELGDFDPRQHTDGYVSEFCFIPNQTEELERRVAGLHR 472
>13951
          Length = 720

 Score = 67.4 bits (163), Expect(2) = 4e-20,   Method: Compositional matrix adjust.
 Identities = 32/69 (46%), Positives = 44/69 (63%), Gaps = 3/69 (4%)
 Frame = -2

Query: 116 KSMQCKVTLLDGSEYGCDVDKRSRGQVLFDKVCEHLNLLEKDYFGLTYRD---AENQKNW 172
           K    +V LLDG     ++D+ + G+ LFDKVC+HL+L+EKDYFGL + D   + + K W
Sbjct: 398 KGFNYEVVLLDGEHVNFELDRNAEGRELFDKVCQHLDLIEKDYFGLQFVDERISNHLKCW 219

Query: 173 LDPAKEIKK 181
           L P K I K
Sbjct: 218 LSPDKRISK 192

 Score = 49.3 bits (116), Expect(2) = 4e-20,   Method: Composition-based stats.
 Identities = 18/45 (40%), Positives = 29/45 (64%)
 Frame = -1

Query: 177 KEIKKQIRSGAWHFSFNVKFYPPDPAQLSEDITRYYLCLQLRDDI 221
           K+ + + + G W F F +KFYPPDP QL E +TR+ + L +  ++
Sbjct: 204 KDFQNRKKGGPWLFDFALKFYPPDPTQLRESLTRWLVVLHVAGEL 70
>28244
          Length = 422

 Score = 78.2 bits (191), Expect = 1e-14,   Method: Composition-based stats.
 Identities = 46/124 (37%), Positives = 67/124 (54%), Gaps = 5/124 (4%)
 Frame = -1

Query: 329 LIYRDRLRINRFAWPKVLKISYKRNNF-YIKIRPGEFEQFESTIG-FKLPNHRAAKRLWK 386
           L++    +I  F WPK+ ++ +K      + +   E  Q +  I  F+L + +A K LWK
Sbjct: 422 LVFEGNXKIGLFFWPKMTRLDFKGKKLTLVAVEDDENGQSQDHIFVFRLQSEKACKHLWK 243

Query: 387 VCVEHHTFFRLLLPEAPP---KKFLTLGSKFRYSGRTQAQTRRASALIDRPAPYFERSSS 443
             VEHH FFRL  P   P   + F  +GS+FRYSGRT+ QT   +    R +  FER  S
Sbjct: 242 CAVEHHAFFRLKGPVQGPNARQNFFRMGSRFRYSGRTEYQTSTMNRA--RRSVKFERKPS 69

Query: 444 KRYT 447
           +RY+
Sbjct: 68  QRYS 57
>08363
          Length = 1878

 Score = 68.2 bits (165), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 43/111 (38%), Positives = 60/111 (54%), Gaps = 1/111 (0%)
 Frame = +1

Query: 805 PGGAKLEISTKEVPVVHTETKTITYESSQVDPGADLEPGVLMSAQXXXXXXXXXXXXXXX 864
           P   ++ + TK VP+V TET+T+TYE        D E GVL+SA                
Sbjct: 151 PDVEEVPVPTKNVPLVKTETRTVTYEREGF--PFDGEDGVLVSASSHSTRMQTIETTTYK 324

Query: 865 XXXVKGGISETRIEKRIVITG-DADIDHDQALAQAIKEAKEQHPDMSVTKV 914
               K G+ ETR+E R+V++  D D D+D ALA AI+   E +PDMSV ++
Sbjct: 325 TE--KDGVQETRVEHRVVLSSTDDDFDYDAALADAIRSVTEFNPDMSVERI 471
>03469
          Length = 1275

 Score = 67.0 bits (162), Expect = 3e-11,   Method: Compositional matrix adjust.
 Identities = 42/104 (40%), Positives = 57/104 (54%), Gaps = 1/104 (0%)
 Frame = -3

Query: 812  ISTKEVPVVHTETKTITYESSQVDPGADLEPGVLMSAQXXXXXXXXXXXXXXXXXXVKGG 871
            + TK VP+V TET+T+TYE        D E GVL+SA                    K G
Sbjct: 1258 VPTKNVPLVKTETRTVTYEREGF--PFDGEDGVLVSASSHSTRMQTIETTTYKTE--KDG 1091

Query: 872  ISETRIEKRIVITG-DADIDHDQALAQAIKEAKEQHPDMSVTKV 914
            + ETR+E R+V++  D D D+D ALA AI+   E +PDMSV ++
Sbjct: 1090 VQETRVEHRVVLSSTDDDFDYDAALADAIRSVTEFNPDMSVERI 959
>05888
          Length = 490

 Score = 56.2 bits (134), Expect = 5e-08,   Method: Compositional matrix adjust.
 Identities = 34/68 (50%), Positives = 39/68 (57%), Gaps = 6/68 (8%)
 Frame = -2

Query: 410 LGSKFRYSGRTQAQTRRASALIDRPAPYFERSSSKRYTM------SRSLDGASVSENHEI 463
           LGSKFRYSGRT  Q R +S  +DRP PYFERS   R T       SRS+D  +   N   
Sbjct: 489 LGSKFRYSGRTLYQARHSSQTLDRPDPYFERSQPARNTYAAPSTRSRSVDELT---NRPD 319

Query: 464 YMKDSVSA 471
           Y KD + A
Sbjct: 318 YWKDDLDA 295
>17536
          Length = 486

 Score = 35.0 bits (79), Expect = 0.13,   Method: Composition-based stats.
 Identities = 16/38 (42%), Positives = 23/38 (60%)
 Frame = -3

Query: 750 GEEVDQSAPEQEQPATVSHEEEQASTIRTSEGLEQKSH 787
           G E+    P++ QP  V+H ++  S I  SEGL QKS+
Sbjct: 346 GNELQHCVPKKFQPLVVTHCKQIVSHITVSEGLGQKSY 233
>12494
          Length = 925

 Score = 29.3 bits (64), Expect = 8.2,   Method: Compositional matrix adjust.
 Identities = 15/40 (37%), Positives = 23/40 (57%)
 Frame = -1

Query: 651 IGGVSSTTQSWVQKLETKTEPVEAEVESTPHPQPLSTEKV 690
           I G+SST   + Q+ E K +    + +STP P PL+ E +
Sbjct: 481 IRGISSTPMRFSQRSEKKNQTNPTQQQSTPPPSPLAPEII 362
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|8393794|ref|NP_058681.1| myotubularin-related protein
1 [Mus musculus]
         (669 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

33160                                                                 409   e-114
04149                                                                  30   3.3  
>33160
          Length = 788

 Score =  409 bits (1050), Expect = e-114,   Method: Compositional matrix adjust.
 Identities = 185/261 (70%), Positives = 220/261 (84%), Gaps = 1/261 (0%)
 Frame = -3

Query: 360 GGYENESAYPNAELIFLEIHNIHVMRESLRKLKEIVYPSIDESHWLSNVDGTHWLEYIRV 419
           GGYE+E +Y NAELIFL+IHNIHVMRES RKLKE  +P+IDE+HWLS ++ THWLE+I+V
Sbjct: 786 GGYESEDSYQNAELIFLDIHNIHVMRESSRKLKEECFPAIDEAHWLSKIESTHWLEHIKV 607

Query: 420 LLAGAVRIADKIESGKTSVVIHCSDGWDRTSQLTSLAMLMLDSYYRTIKGFEALIEKEWI 479
           +LAGAVRIAD +ES K SV++HCSDGWDRT+QLTSLAMLMLD +YRTI+GFE L+EKEWI
Sbjct: 606 ILAGAVRIADTVESNKRSVLVHCSDGWDRTAQLTSLAMLMLDPHYRTIRGFEVLVEKEWI 427

Query: 480 SFGHRFALRVGHGDDNHADADRSPIFLQFIDCVWQMTRQFPSAFEFNELFLITILDHLYS 539
           SFGH+F  RVGHG+D H+D +RSP+FLQF+DCVWQMTRQFP+AFEFNE FLITILDHLYS
Sbjct: 426 SFGHKFRQRVGHGEDKHSDDNRSPVFLQFVDCVWQMTRQFPNAFEFNEHFLITILDHLYS 247

Query: 540 CLFGTFLCNCEQQRIKEDVYTNTISLWSYINSQLDEFSNPFFVNY-ENHVLYPVASMSHL 598
           CLFGTFL +C+    KE V   T SLWS+IN QL+EF+NP +  Y   HV++PVAS+  +
Sbjct: 246 CLFGTFLFSCQMPADKEKVKERTQSLWSFINCQLEEFTNPLYAAYVHAHVIFPVASLRRI 67

Query: 599 ELWVNYYVRWNPRMRPQMPIH 619
            LW  YY RWNPRMRPQ PIH
Sbjct: 66  HLWTGYYCRWNPRMRPQEPIH 4
>04149
          Length = 1107

 Score = 30.0 bits (66), Expect = 3.3,   Method: Compositional matrix adjust.
 Identities = 13/28 (46%), Positives = 17/28 (60%)
 Frame = +3

Query: 562 TISLWSYINSQLDEFSNPFFVNYENHVL 589
            + LWSYI ++   F   FFV+Y NH L
Sbjct: 372 CVCLWSYIAARHYFFLCYFFVSYRNHFL 455
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|9506983|ref|NP_062284.1| protein phosphatase 2a,
catalytic subunit, alpha isoform [Mus musculus]
         (309 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

08242                                                                 407   e-114
01173                                                                 295   1e-80
06084                                                                 295   2e-80
06264                                                                 288   2e-78
25536                                                                 285   1e-77
30980                                                                 177   4e-45
19040                                                                 173   1e-43
18336                                                                 106   1e-30
21146                                                                 118   3e-27
04295                                                                  65   4e-11
18967                                                                  62   2e-10
32330                                                                  53   2e-07
36367                                                                  47   8e-06
00990                                                                  33   0.14 
19872                                                                  28   3.5  
17953                                                                  27   7.8  
29461                                                                  27   9.0  
>08242
          Length = 3368

 Score =  407 bits (1046), Expect = e-114,   Method: Compositional matrix adjust.
 Identities = 189/275 (68%), Positives = 227/275 (82%), Gaps = 2/275 (0%)
 Frame = -1

Query: 37   EILTKESNVQEVRCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVET 96
            EIL +ESNVQ V  PVTVCGD+HGQF+DL ELF++GG  PDTNYLFMGD+VDRG+YSVET
Sbjct: 3368 EILVEESNVQRVDSPVTVCGDIHGQFYDLKELFKVGGDVPDTNYLFMGDFVDRGFYSVET 3189

Query: 97   VTLLVALKVRYRERITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLT 156
              LL+ALKVRY +RIT++RGNHESRQITQVYGFYDECLRKYG+  VW+Y T++FDYL L+
Sbjct: 3188 FLLLLALKVRYPDRITLIRGNHESRQITQVYGFYDECLRKYGSITVWRYCTEIFDYLSLS 3009

Query: 157  ALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWSDPDDRGGWGISPRGA 216
            A++DG+IFC+HGGLSPSI TLD IR++DR QEVPH+GPMCDLLWSDP+D  GWG+SPRGA
Sbjct: 3008 AIIDGKIFCVHGGLSPSIQTLDQIRSIDRKQEVPHDGPMCDLLWSDPEDMQGWGVSPRGA 2829

Query: 217  GYTFGQDISETFNHANGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIM 276
            GY FG D+   FN AN + L+ RAHQLVMEGY W  +  V+T++SAPNYCYRCGN AAI+
Sbjct: 2828 GYLFGSDVVSQFNAANXIDLICRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAIL 2649

Query: 277  ELDDTLKYSFLQFDPAPR--RGEPHVTRRTPDYFL 309
            ELD+ L+  F  F+ AP+  RG P   +  PDYFL
Sbjct: 2648 ELDEHLQRDFTIFEAAPQEARGIPS-KKPQPDYFL 2547
>01173
          Length = 2619

 Score =  295 bits (756), Expect = 1e-80,   Method: Compositional matrix adjust.
 Identities = 135/279 (48%), Positives = 194/279 (69%), Gaps = 1/279 (0%)
 Frame = -1

Query: 22   QLSESQVKSLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYL 81
            QL+ES+++ LC K++EI   +  + E+  P+ +CGD+HGQ++DL+ LF  GG  P++NYL
Sbjct: 2610 QLTESEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYL 2431

Query: 82   FMGDYVDRGYYSVETVTLLVALKVRYRERITILRGNHESRQITQVYGFYDECLRKYGNAN 141
            F+GDYVDRG  S+ET+ LL+A K++Y E   +LRGNHE   I ++YGFYDEC R+Y N  
Sbjct: 2430 FLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRY-NIK 2254

Query: 142  VWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWS 201
            +WK FTD F+ LP+ A++D +IFC HGGLSP + +++ IR + R  +VP +G +CDLLWS
Sbjct: 2253 LWKTFTDCFNCLPIAAIIDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWS 2074

Query: 202  DPD-DRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGYNWCHDRNVVTIF 260
            DPD +  GWG + RG  +TFG ++   F H + L L+ RAHQ+V +GY +   R +VT+F
Sbjct: 2073 DPDKETMGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLF 1894

Query: 261  SAPNYCYRCGNQAAIMELDDTLKYSFLQFDPAPRRGEPH 299
            SAPNYC    N  A+M +D+TL  SF    PA ++  P+
Sbjct: 1893 SAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKKKFPY 1777
>06084
          Length = 1739

 Score =  295 bits (754), Expect = 2e-80,   Method: Compositional matrix adjust.
 Identities = 139/251 (55%), Positives = 179/251 (71%)
 Frame = -2

Query: 59   HGQFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYRERITILRGNH 118
            HGQF+DLMELF+ GG+ PDTNY+FMGD+VDRGY+S+ET TLL+ LK ++ ++I +LRGNH
Sbjct: 1738 HGQFYDLMELFKTGGEMPDTNYVFMGDFVDRGYFSLETFTLLLTLKAKWPDKIVLLRGNH 1559

Query: 119  ESRQITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLD 178
            ESRQITQ+YGFYDEC  KYGNAN W+Y   +FD L + A++D  I C+HGGLSP I T+D
Sbjct: 1558 ESRQITQIYGFYDECQTKYGNANAWRYCCRVFDLLTIAAIIDECILCVHGGLSPDIKTID 1379

Query: 179  HIRALDRLQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNHANGLTLVS 238
             IR ++R QE+PH+G  CDL+WSDP+D   W +SPRGAG+ FG  ++  F  +N L L+ 
Sbjct: 1378 QIRTIERNQEIPHKGAFCDLVWSDPEDVDTWAMSPRGAGWLFGAKVTAEFVASNNLKLIC 1199

Query: 239  RAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDTLKYSFLQFDPAPRRGEP 298
            RAHQLV EGY +  D  +VT++SAPNYCYRCGN AA++   D   +    F   P     
Sbjct: 1198 RAHQLVHEGYKYMFDEKLVTVWSAPNYCYRCGNIAAVLSFTDAEHHEAKLFKAVPDSERV 1019

Query: 299  HVTRRTPDYFL 309
               R    YFL
Sbjct: 1018 IPPRTQTPYFL 986
>06264
          Length = 999

 Score =  288 bits (738), Expect = 2e-78,   Method: Compositional matrix adjust.
 Identities = 132/274 (48%), Positives = 189/274 (68%), Gaps = 1/274 (0%)
 Frame = -3

Query: 27  QVKSLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDY 86
           +++ LC K++EI   +  + E+  P+ +CGD+HGQ++DL+ LF  GG  P++NYLF+GDY
Sbjct: 997 EIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDY 818

Query: 87  VDRGYYSVETVTLLVALKVRYRERITILRGNHESRQITQVYGFYDECLRKYGNANVWKYF 146
           VDRG  S+ET+ LL+A K++Y E   +LRGNHE   I ++YGFYDEC R+Y N  +WK F
Sbjct: 817 VDRGRQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRY-NIKLWKTF 641

Query: 147 TDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWSDPD-D 205
           TD F+ LP+ A++D +IFC HGGLSP + +++ IR + R  +VP +G +CDLLWSDPD +
Sbjct: 640 TDCFNCLPIAAIIDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKE 461

Query: 206 RGGWGISPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNY 265
             GWG S RG  +TFG ++   F H + L L+ RAHQ+V +GY +   R +VT+FSAPNY
Sbjct: 460 TMGWGESDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNY 281

Query: 266 CYRCGNQAAIMELDDTLKYSFLQFDPAPRRGEPH 299
           C    N  A+M +D+TL  SF    PA ++  P+
Sbjct: 280 CGEFDNAGAMMSVDETLMCSFQILKPADKKKFPY 179
>25536
          Length = 486

 Score =  285 bits (730), Expect = 1e-77,   Method: Compositional matrix adjust.
 Identities = 133/148 (89%), Positives = 145/148 (97%)
 Frame = +1

Query: 1   MDEKLFTKELDQWIEQLNECKQLSESQVKSLCEKAKEILTKESNVQEVRCPVTVCGDVHG 60
           ++E+   K+LDQWIEQLN+CKQLSE+QVK+LCEKAKEIL+KESNVQEV+CPVTVCGDVHG
Sbjct: 43  VEERAAAKDLDQWIEQLNDCKQLSENQVKTLCEKAKEILSKESNVQEVKCPVTVCGDVHG 222

Query: 61  QFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYRERITILRGNHES 120
           QFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETV+LLVALKVR+R+RITILRGNHES
Sbjct: 223 QFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVSLLVALKVRFRDRITILRGNHES 402

Query: 121 RQITQVYGFYDECLRKYGNANVWKYFTD 148
           RQITQVYGFYDECLRKYGNANVWKYFTD
Sbjct: 403 RQITQVYGFYDECLRKYGNANVWKYFTD 486
>30980
          Length = 765

 Score =  177 bits (450), Expect = 4e-45,   Method: Compositional matrix adjust.
 Identities = 80/83 (96%), Positives = 82/83 (98%)
 Frame = +3

Query: 227 TFNHANGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDTLKYSF 286
           TFNH+NGLTL+SRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDD LKYSF
Sbjct: 3   TFNHSNGLTLISRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDALKYSF 182

Query: 287 LQFDPAPRRGEPHVTRRTPDYFL 309
           LQFDPAPRRGEPHVTRRTPDYFL
Sbjct: 183 LQFDPAPRRGEPHVTRRTPDYFL 251
>19040
          Length = 452

 Score =  173 bits (438), Expect = 1e-43,   Method: Compositional matrix adjust.
 Identities = 76/151 (50%), Positives = 107/151 (70%)
 Frame = -3

Query: 29  KSLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVD 88
           + LC K++EI  ++  + E+  P+ +CGD+HGQ+ DL+ LF  GG  P  NYLF+GDYVD
Sbjct: 450 RGLCLKSREIFLQQPILLELEAPLIICGDIHGQYTDLLRLFEYGGFPPAANYLFLGDYVD 271

Query: 89  RGYYSVETVTLLVALKVRYRERITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTD 148
           RG  S+ET+ LL+A K++Y E   +LRGNHE   I ++YGFYDEC R+Y N  +WK FTD
Sbjct: 270 RGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRY-NVKLWKTFTD 94

Query: 149 LFDYLPLTALVDGQIFCLHGGLSPSIDTLDH 179
            F+ LP+ A++D +IFC HGGLSP +  ++ 
Sbjct: 93  CFNCLPVAAIIDEKIFCCHGGLSPDLQGMEQ 1
>18336
          Length = 465

 Score =  106 bits (265), Expect(3) = 1e-30,   Method: Compositional matrix adjust.
 Identities = 50/108 (46%), Positives = 74/108 (68%)
 Frame = +2

Query: 22  QLSESQVKSLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYL 81
           QLSE + ++    ++ IL    + + +R    +CGD+HGQ++DL+ LF  GG  P++NYL
Sbjct: 11  QLSEQK*EAYV*ISRNILESAYSFR-IRSTT*ICGDIHGQYYDLLRLFEYGGFPPESNYL 187

Query: 82  FMGDYVDRGYYSVETVTLLVALKVRYRERITILRGNHESRQITQVYGF 129
           F+GDYVDRG  S+ET+ LL+A K++Y E   +LRGNHE   I ++YGF
Sbjct: 188 FLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGF 331

 Score = 43.5 bits (101), Expect(3) = 1e-30,   Method: Compositional matrix adjust.
 Identities = 19/35 (54%), Positives = 26/35 (74%)
 Frame = +1

Query: 130 YDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIF 164
           YDEC R+Y N  +WK FTD F+ LP+ A++D +IF
Sbjct: 331 YDECKRRY-NIKLWKTFTDCFNCLPIAAIIDVKIF 432

 Score = 20.8 bits (42), Expect(3) = 1e-30,   Method: Compositional matrix adjust.
 Identities = 7/11 (63%), Positives = 8/11 (72%)
 Frame = +3

Query: 164 FCLHGGLSPSI 174
            C HGGLSP +
Sbjct: 429 LCCHGGLSPDL 461
>21146
          Length = 408

 Score =  118 bits (296), Expect = 3e-27,   Method: Compositional matrix adjust.
 Identities = 53/59 (89%), Positives = 56/59 (94%)
 Frame = +3

Query: 192 EGPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGYNW 250
           +GPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNH+NGLTL+SRAHQLVME   W
Sbjct: 114 QGPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNHSNGLTLISRAHQLVMEVMFW 290
>04295
          Length = 748

 Score = 65.1 bits (157), Expect = 4e-11,   Method: Compositional matrix adjust.
 Identities = 29/75 (38%), Positives = 46/75 (61%)
 Frame = -1

Query: 223 DISETFNHANGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDTL 282
           D+   F + + L L++RAHQ+V +GY +   R +VT+FSAPNYC    N   +M +D+TL
Sbjct: 745 DVVSKFLNRHDLDLITRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDETL 566

Query: 283 KYSFLQFDPAPRRGE 297
             SF    P+ ++ +
Sbjct: 565 MCSFQILKPSEKKAK 521
>18967
          Length = 440

 Score = 62.4 bits (150), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 32/76 (42%), Positives = 42/76 (55%)
 Frame = +2

Query: 234 LTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDTLKYSFLQFDPAP 293
           L L+ RAHQLV EG  +  +  +VT++SAPNYCYRCGN AAI+  +   +     F   P
Sbjct: 2   LDLICRAHQLVNEGIKYMFEGKLVTVWSAPNYCYRCGNVAAILSFETAQQRQTKIFLAVP 181

Query: 294 RRGEPHVTRRTPDYFL 309
                   + T  YFL
Sbjct: 182 DSERVIPKQNTTPYFL 229
>32330
          Length = 226

 Score = 52.8 bits (125), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 23/23 (100%), Positives = 23/23 (100%)
 Frame = +1

Query: 287 LQFDPAPRRGEPHVTRRTPDYFL 309
           LQFDPAPRRGEPHVTRRTPDYFL
Sbjct: 1   LQFDPAPRRGEPHVTRRTPDYFL 69
>36367
          Length = 827

 Score = 47.4 bits (111), Expect = 8e-06,   Method: Compositional matrix adjust.
 Identities = 43/152 (28%), Positives = 65/152 (42%), Gaps = 25/152 (16%)
 Frame = +1

Query: 167 HGGL-SPSIDTLDHIRALDRLQEVPHEGPMCD------LLWSDP---------------D 204
           HGG+ SP  +   H+ A++++  VP   P  D      +LWSDP               +
Sbjct: 1   HGGIPSPENEGGGHLEAINKIP-VPLSDPEVDSPMAWEILWSDPISVDLVSPEVLKDMKE 177

Query: 205 DRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPN 264
             G    S RG  + F  +    F   NGL+ V RAH++   G+       ++T+FS+  
Sbjct: 178 HHGFTFNSRRGTAHFFSCNALLAFLERNGLSHVIRAHEVQEVGFQVQQQGKLLTVFSSSR 357

Query: 265 YCYRCGNQAAIMELDDTLKYSFLQFD---PAP 293
           YC   G+  A   L D  K   ++ D   P P
Sbjct: 358 YC--GGSNEAACVLADNYKLRMIRIDTT*PGP 447
>00990
          Length = 3161

 Score = 33.1 bits (74), Expect = 0.14,   Method: Compositional matrix adjust.
 Identities = 14/52 (26%), Positives = 21/52 (40%)
 Frame = -3

Query: 8    KELDQWIEQLNECKQLSESQVKSLCEKAKEILTKESNVQEVRCPVTVCGDVH 59
            + +  W+  L     LS     SL   + ++L   S V  + CP T C   H
Sbjct: 1581 RPIVPWVPSLVRVASLSPGSWSSLSLPSMDLLAPRSIVPPLHCPPTACRPSH 1426
>19872
          Length = 446

 Score = 28.5 bits (62), Expect = 3.5,   Method: Compositional matrix adjust.
 Identities = 15/45 (33%), Positives = 23/45 (51%), Gaps = 1/45 (2%)
 Frame = -1

Query: 181 RALDRLQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFG-QDI 224
           R + RLQEV   GP+C ++      + G  +  R  G  +G QD+
Sbjct: 218 RQIGRLQEVSRAGPLCGVVAQHLTKQXGLVVEVRVLGEVWGKQDV 84
>17953
          Length = 626

 Score = 27.3 bits (59), Expect = 7.8,   Method: Compositional matrix adjust.
 Identities = 16/52 (30%), Positives = 24/52 (46%), Gaps = 6/52 (11%)
 Frame = -2

Query: 232 NGLTLVSRAHQLVMEGYNWCHDR------NVVTIFSAPNYCYRCGNQAAIME 277
           N L  + RAH+    GY            +++TIFSAPNY     N+  ++ 
Sbjct: 616 NNLLSIIRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKVQLLS 461
>29461
          Length = 456

 Score = 27.3 bits (59), Expect = 9.0,   Method: Compositional matrix adjust.
 Identities = 9/19 (47%), Positives = 15/19 (78%)
 Frame = +2

Query: 133 CLRKYGNANVWKYFTDLFD 151
           C +++  ANVW+YF D++D
Sbjct: 305 C*KEFLKANVWRYFCDMYD 361
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|111494232|ref|NP_067505.2| solute carrier family 4
(anion exchanger), member 8 [Mus musculus]
         (1089 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

14939                                                                 219   e-113
17976                                                                 181   3e-53
18083                                                                 131   1e-30
15748                                                                  32   1.7  
>14939
          Length = 1186

 Score =  219 bits (557), Expect(2) = e-113,   Method: Compositional matrix adjust.
 Identities = 100/150 (66%), Positives = 120/150 (80%)
 Frame = -1

Query: 719  FPTRVRSMVSDFAVFLTIFTMVVLDFLIGVPSPKLQVPNVFKPTRDDRGWFINPIGPNPW 778
            FPT VR+ +SDF+V + I +MVV D  +G+P+PKL VP  F PT   RGW INP+G NPW
Sbjct: 1114 FPTMVRATLSDFSVLIAILSMVVFDICVGLPTPKLHVPETFAPTNPKRGWLINPVGENPW 935

Query: 779  WTVIAAIIPALLCTILIFMDQQITAVIINRKEHKLKKGCGYHLDLLMVAVMLGVCSIMGL 838
            WT +AA+IPALL  ILIFMDQQITAVI+NRKE+KL KG GYHLDL +V+V++ +CS +GL
Sbjct: 934  WTTLAAVIPALLAVILIFMDQQITAVIVNRKENKLVKGRGYHLDLFIVSVLIILCSFLGL 755

Query: 839  PWFVAATVLSITHVNSLKLESECSAPGEQP 868
            PWFVAATVLSI HVNSLK ES+CSAP   P
Sbjct: 754  PWFVAATVLSINHVNSLKKESQCSAPANNP 665

 Score =  209 bits (532), Expect(2) = e-113,   Method: Compositional matrix adjust.
 Identities = 105/221 (47%), Positives = 149/221 (67%), Gaps = 1/221 (0%)
 Frame = -3

Query: 864  PGEQPKFLGIREQRVTGLMIFVLMGCSVFMTAVLKFIPMPVLYGVFLYMGVSSLQGIQFF 923
            PGEQPKFLG+REQRVTG+ IF+L+G SV +T+VLKFIPMPVLYGVFLYMGVSSL+G+Q  
Sbjct: 680  PGEQPKFLGVREQRVTGITIFLLIGISVMLTSVLKFIPMPVLYGVFLYMGVSSLRGMQLV 501

Query: 924  DRLKLFGMPAKHQPDFIYLRHVPLRKVHLFTLVQLTCLVLLWVIKA-SPAAIVFPMMVLA 982
             R+ ++ MPAK+Q D ++LRHV   +VHLFT++Q+ CL+ LW IK+    +I FP+MVLA
Sbjct: 500  HRVLIWFMPAKYQWDLMFLRHVRTNRVHLFTIIQIFCLLCLWGIKSYKKISIAFPIMVLA 321

Query: 983  LVFVRKVMDLCFSKRELSWLDDLMPESXXXXXXXXXXXXXXXXXXMLDIGGDKFPLESRK 1042
            + FVRK +D  F +REL WLDD+MPE+                  +++ G    PL    
Sbjct: 320  MCFVRKALDWVFDQRELKWLDDIMPEAHKRAKEDEIKKQEEQRFSLIE-GSTSIPLA--- 153

Query: 1043 LLSSPGKSSSFRCDPSEINISDEMPKTTVWKALSINSGNTK 1083
             +    +  + + +  ++NIS+EM +T +WK++  N  ++ 
Sbjct: 152  -MGLNMEHITIQAEMDQVNISEEMSRTALWKSIMHNESSSN 33
>17976
          Length = 781

 Score =  181 bits (459), Expect(2) = 3e-53,   Method: Compositional matrix adjust.
 Identities = 96/214 (44%), Positives = 132/214 (61%), Gaps = 17/214 (7%)
 Frame = +1

Query: 872  GIREQRVTGLMIFVLMGCSVFMTAVLKFIPMPVLYGVFLYMGVSSLQGIQFFDRLKLFGM 931
            G+REQR+TGLM+ +L G +V  TAVLKFIPM VLYGVFLYMG+++L+G+QF DR+ L   
Sbjct: 139  GVREQRLTGLMVGLLSGLTVLFTAVLKFIPMAVLYGVFLYMGMAALKGMQFIDRILLMLK 318

Query: 932  PAKHQPDFIYLRHVPLRKVHLFTLVQLTCLVLLWVIKA-SPAAIVFPMMVLALVFVRKVM 990
            PAK+QPD  YLRHVP+++VH+FT +Q+ CL +LWVIK+    +I+FP+MVL   FVRK +
Sbjct: 319  PAKYQPDTTYLRHVPIKRVHIFTAIQVVCLAVLWVIKSVKSVSIIFPIMVLGTCFVRKGL 498

Query: 991  DLCFSKRELSWLDDLMPESXXXXXXXXXXXXXXXXXXMLD-----IGGD------KFPLE 1039
            D  F++ EL WLDD+MP++                          +G D      +F +E
Sbjct: 499  DYLFTQGELKWLDDIMPDAAKKKKEDASQLHHKDAEADRKEKESLLGEDAYNRLVEFKVE 678

Query: 1040 SRKLLSSPGKSSSF-----RCDPSEINISDEMPK 1068
              KL  + GK          CD   INI +E+ +
Sbjct: 679  HEKLDVADGKYGQRFTHRPSCDTDRINIIEELSR 780

 Score = 47.4 bits (111), Expect(2) = 3e-53,   Method: Compositional matrix adjust.
 Identities = 24/37 (64%), Positives = 29/37 (78%), Gaps = 1/37 (2%)
 Frame = +3

Query: 837 GLP-WFVAATVLSITHVNSLKLESECSAPGEQPKFLG 872
           GLP   VAATV ++ H+ SLK ESEC+APGE+P FLG
Sbjct: 30  GLPLGTVAATVSALAHIMSLKKESECTAPGERPTFLG 140
>18083
          Length = 865

 Score =  131 bits (330), Expect = 1e-30,   Method: Composition-based stats.
 Identities = 78/202 (38%), Positives = 122/202 (60%), Gaps = 4/202 (1%)
 Frame = -3

Query: 793 ILIFMDQQITAVIINRKEHKLKKGCGYHLDLLMVAVMLGVCSIMGLPWFVAATVLSITHV 852
           +L FMDQ I+A ++N  ++K+KKG  YH DLL++AV+  V S+   P   AA   S  HV
Sbjct: 863 LLFFMDQNISAALVNAPQNKMKKGTAYHWDLLVIAVVNAVISVFAFPMVHAALPHSPLHV 684

Query: 853 NSLKLESECSAPGEQPK-FLGIREQRVTGLMIFVLMGCSVFMTAVLKFIPMPVLYGVFLY 911
            +L    E    G   +  + +RE R+T ++  +L+G S+ +  VL +IP PVLYG+FLY
Sbjct: 683 RALADVEERVVQGHITQTVVRVRETRITAILSHILIGLSILIMFVLAYIPTPVLYGLFLY 504

Query: 912 MGVSSLQGIQFFDRLKLFGMPAKHQPDFIYLRHVPLRKVHLFTLVQLTCLVLLWV---IK 968
           + +++L   Q F+R+ LF       P   Y+RHVP RKVH+FTL+QL  LV+L V   + 
Sbjct: 503 VAITALYDNQMFERITLFFTEQSAYPPTHYIRHVPQRKVHIFTLIQLLQLVVLCVFGFVS 324

Query: 969 ASPAAIVFPMMVLALVFVRKVM 990
            +   + FP+++  L+ +R ++
Sbjct: 323 FAYLKMFFPVLIFLLIPIRHMV 258
>15748
          Length = 1249

 Score = 31.6 bits (70), Expect = 1.7,   Method: Compositional matrix adjust.
 Identities = 31/119 (26%), Positives = 56/119 (47%), Gaps = 5/119 (4%)
 Frame = +1

Query: 147 EDGGERWSKPYVATLSLHSLFELRSCLINGSVL-----LDMRASSIEEISDLILDQQELL 201
           ++ G RW   Y+ ++ L  L  L   L+  +++     LD R++S+EE  DLI       
Sbjct: 445 KEDG*RWLSTYLLSVCLCXLGTLNLSLLFMAIVFESTPLDQRSASVEEDRDLIHHFAPKK 624

Query: 202 RDLSDSVRVKVREALLKKHHHQNERRRNNLIPIVRSFAEVGKKQSDPHSMDRDGQTVSP 260
           R +   VR++      +KH H N   +N +      FAE+ K   + ++++   Q + P
Sbjct: 625 RPV--GVRIETFRTDTRKHTHTN---KNPVGS*DLKFAELFKSNYNSNALNSSLQQLIP 786
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31542427|ref|NP_031814.2| casein kinase 2, alpha 1
polypeptide [Mus musculus]
         (391 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

03508                                                                 402   e-113
00638                                                                 145   3e-47
12704                                                                 126   1e-29
01060                                                                 106   2e-23
14126                                                                 104   6e-23
01707                                                                  97   1e-20
04591                                                                  93   2e-19
32000                                                                  87   2e-17
04138                                                                  87   2e-17
29581                                                                  85   4e-17
01756                                                                  76   2e-14
21079                                                                  76   2e-14
15910                                                                  72   3e-13
26560                                                                  69   4e-12
23319                                                                  69   4e-12
00300                                                                  62   4e-10
13212                                                                  62   5e-10
12786                                                                  61   6e-10
12721                                                                  61   6e-10
01392                                                                  61   9e-10
30755                                                                  60   1e-09
28638                                                                  60   1e-09
01966                                                                  60   1e-09
14420                                                                  57   9e-09
27405                                                                  57   2e-08
18921                                                                  57   2e-08
18287                                                                  56   2e-08
31885                                                                  55   4e-08
03294                                                                  55   5e-08
19761                                                                  55   5e-08
26711                                                                  55   5e-08
18484                                                                  55   6e-08
09606                                                                  54   9e-08
19094                                                                  54   1e-07
13592                                                                  53   2e-07
18401                                                                  50   1e-06
03240                                                                  49   2e-06
21433                                                                  49   4e-06
13078                                                                  49   4e-06
31489                                                                  48   9e-06
04852                                                                  46   2e-05
13066                                                                  46   2e-05
07940                                                                  46   3e-05
11185                                                                  45   7e-05
00715                                                                  44   1e-04
17975                                                                  42   4e-04
37602                                                                  41   0.001
14116                                                                  40   0.001
01718                                                                  40   0.002
01106                                                                  39   0.003
26009                                                                  39   0.004
05084                                                                  39   0.004
06358                                                                  38   0.005
00392                                                                  38   0.007
21800                                                                  37   0.012
32359                                                                  28   0.020
27546                                                                  36   0.030
02638                                                                  35   0.039
18481                                                                  35   0.053
28157                                                                  35   0.066
29360                                                                  34   0.079
15931                                                                  33   0.13 
19301                                                                  33   0.16 
11801                                                                  33   0.20 
26909                                                                  33   0.22 
29590                                                                  33   0.24 
14104                                                                  33   0.26 
12672                                                                  31   0.98 
27274                                                                  30   1.2  
35032                                                                  30   1.4  
37063                                                                  30   1.5  
17932                                                                  30   1.8  
16350                                                                  30   2.0  
20513                                                                  29   3.3  
18663                                                                  29   4.0  
20773                                                                  28   5.2  
28419                                                                  28   6.3  
20152                                                                  28   9.2  
>03508
          Length = 1463

 Score =  402 bits (1034), Expect = e-113,   Method: Compositional matrix adjust.
 Identities = 187/233 (80%), Positives = 201/233 (86%)
 Frame = +1

Query: 1   MSGPVPSRARVYTDVNTHRPREYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINIT 60
           +S P+PSRARVY DVNTH+ REYWDYESHVVEWGNQDDYQ+VRKLGRGKYSEVFEAIN+T
Sbjct: 481 VSMPLPSRARVYADVNTHKAREYWDYESHVVEWGNQDDYQIVRKLGRGKYSEVFEAINVT 660

Query: 61  NNEXXXXXXXXXXXXXXXXXXXXXLENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTD 120
           NNE                     LENLRGG N+ITL  IVKDPVSRTPAL+FEHVNNTD
Sbjct: 661 NNEKCVIKILKPVKKKKIKREIKILENLRGGTNVITLLAIVKDPVSRTPALIFEHVNNTD 840

Query: 121 FKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAE 180
           FKQLYQT TDYDIRFY+YE++KALD+CHSMGIMHRDVKPHNVMIDHE++KLRLIDWGLAE
Sbjct: 841 FKQLYQTFTDYDIRFYLYELMKALDFCHSMGIMHRDVKPHNVMIDHENKKLRLIDWGLAE 1020

Query: 181 FYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFF 233
           FYHPG EYNVRVASRYFKGPELL+DYQMYDYSLDMWSLGCM ASMIFRKEP  
Sbjct: 1021FYHPGMEYNVRVASRYFKGPELLLDYQMYDYSLDMWSLGCMFASMIFRKEPLL 1179

 Score =  186 bits (472), Expect = 1e-47,   Method: Compositional matrix adjust.
 Identities = 89/115 (77%), Positives = 97/115 (84%), Gaps = 3/115 (2%)
 Frame = +2

Query: 216  WSLGCMLASM---IFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDI 272
            W+ G   A +      K PFFHGHDNYDQLVRIAKVLGT+DLY YI+KY I+LDPRFNDI
Sbjct: 1118 WTCGVWAACLPA*SSGKSPFFHGHDNYDQLVRIAKVLGTDDLYGYIEKYQIDLDPRFNDI 1297

Query: 273  LGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTV 327
            LGRHSRKRWERFVHSENQHL+SPEALDFLDKLLRYDH  RLTAREAM+HPYF  +
Sbjct: 1298 LGRHSRKRWERFVHSENQHLISPEALDFLDKLLRYDHNERLTAREAMDHPYFXPI 1462
>00638
          Length = 1595

 Score =  145 bits (367), Expect(2) = 3e-47,   Method: Compositional matrix adjust.
 Identities = 65/75 (86%), Positives = 71/75 (94%)
 Frame = +2

Query: 85  LENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKAL 144
           LENLRGG N+ITL  IVKDPVSRTPAL+FEHVNNTDFKQLYQT TDYDIRFY+YE++KAL
Sbjct: 278 LENLRGGTNVITLLAIVKDPVSRTPALIFEHVNNTDFKQLYQTFTDYDIRFYLYELMKAL 457

Query: 145 DYCHSMGIMHRDVKP 159
           D+CHSMGIMHRDVKP
Sbjct: 458 DFCHSMGIMHRDVKP 502

 Score = 61.2 bits (147), Expect(2) = 3e-47,   Method: Compositional matrix adjust.
 Identities = 27/29 (93%), Positives = 29/29 (100%)
 Frame = +1

Query: 35  NQDDYQLVRKLGRGKYSEVFEAINITNNE 63
           NQDDYQ+VRKLGRGKYSEVFEAIN+TNNE
Sbjct: 127 NQDDYQIVRKLGRGKYSEVFEAINVTNNE 213
>12704
          Length = 641

 Score =  126 bits (317), Expect = 1e-29,   Method: Compositional matrix adjust.
 Identities = 56/63 (88%), Positives = 61/63 (96%)
 Frame = +3

Query: 1   MSGPVPSRARVYTDVNTHRPREYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINIT 60
           ++ P+PSRARVY DVNTH+PREYWDYESHVVEWGNQDDYQ+VRKLGRGKYSEVFEAINIT
Sbjct: 423 ITMPLPSRARVYADVNTHKPREYWDYESHVVEWGNQDDYQIVRKLGRGKYSEVFEAINIT 602

Query: 61  NNE 63
           NNE
Sbjct: 603 NNE 611
>01060
          Length = 1800

 Score =  106 bits (264), Expect = 2e-23,   Method: Compositional matrix adjust.
 Identities = 66/242 (27%), Positives = 123/242 (50%), Gaps = 7/242 (2%)
 Frame = +1

Query: 93  NIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQ------TLTDYDIRFYMYEILKALDY 146
           NI+ L D++ +       LVFE ++  D K           L    ++ Y+++I+  + +
Sbjct: 253 NIVCLEDVIME--DERLFLVFEFLS-MDLKMYIDKFPEGVVLDRRLVKSYVFQIVTGIXF 423

Query: 147 CHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAE-FYHPGQEYNVRVASRYFKGPELLVD 205
           CH   I+HRD+KP N++I+H    +++ D+G+A  F  P + Y   V + +++ PE+L+ 
Sbjct: 424 CHQRRIVHRDLKPQNLLINHTG-AIKIADFGMARTFALPVRAYTHEVVTLWYRAPEILMG 600

Query: 206 YQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIEL 265
              Y   +D+WS+G + A M+ R  P F G    DQL +I +++GT     + + + +  
Sbjct: 601 ASKYSTPVDVWSIGTIFADMLIRT-PIFKGDSEIDQLFKIFRIIGTPTEQTWPEFHKL-- 771

Query: 266 DPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFY 325
            P FN +        W+    SE    +    LD +++ L+ D   R++ ++ ++H YF 
Sbjct: 772 -PAFNGMF-----PLWKEGKLSETLTDLDSLGLDLIERTLKCDPAQRISCKKMLQHAYFL 933

Query: 326 TV 327
            V
Sbjct: 934 NV 939
>14126
          Length = 1265

 Score =  104 bits (260), Expect = 6e-23,   Method: Compositional matrix adjust.
 Identities = 73/256 (28%), Positives = 128/256 (50%), Gaps = 10/256 (3%)
 Frame = +3

Query: 92  PNIITLADIVKDPVSRTPA---LVFEHVNNTDFKQLYQT----LTDYDIRFYMYEILKAL 144
           PN++ L D+  + ++       LVFE++ +     L +     L    I+  M ++L  +
Sbjct: 378 PNVVRLLDVSHNTITDREIRLNLVFEYIEHDLATYLAKCPSPGLGPDRIKDLMLQLLNGV 557

Query: 145 DYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLV 204
           D+ HS  I+HRD+KP N++I  + R L+L D+GLA  Y         V + +++ PE+L+
Sbjct: 558 DFLHSNRIVHRDLKPQNLLISKDGR-LKLADFGLARIYSFHMALTTVVVTLWYRSPEVLM 734

Query: 205 DYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIE 264
             + Y  S+D+WS GC+ A + F +   F G   +DQL +I +V+G     D+ +  ++ 
Sbjct: 735 QAE-YGTSVDIWSCGCIFAEL-FTRRALFKGSSEFDQLKKIFEVIGLPPAGDWPEGVSVH 908

Query: 265 LDPRFNDILGRHSRKRWERFVHSENQHLV---SPEALDFLDKLLRYDHQSRLTAREAMEH 321
                        R  +        Q LV    P+A D ++K+L +    R+++RE++ H
Sbjct: 909 -------------RNSFRPTPPVPLQTLVPEMDPQAKDLMEKMLVFKSGRRISSRESLLH 1049

Query: 322 PYFYTVVKDQARMSST 337
           PY    + D  R SS+
Sbjct: 1050PYLRDDL-DSIRTSSS 1094
>01707
          Length = 757

 Score = 96.7 bits (239), Expect = 1e-20,   Method: Compositional matrix adjust.
 Identities = 63/223 (28%), Positives = 114/223 (51%), Gaps = 9/223 (4%)
 Frame = +1

Query: 37  DDYQLVRKLGRGKYSEVFEAINITNNEXXXXXXXXXXX-----XXXXXXXXXXLENLRGG 91
           + Y+ + K+G G Y  VF+  N   ++                          L+ L+  
Sbjct: 64  EKYEKIGKIGEGSYGVVFKCRNKETSQLVAIKKFVESEDDPLIKKIAMREIRMLKQLKH- 240

Query: 92  PNIITLADIVKDPVSRTPALVFEHVNNTDFKQL---YQTLTDYDIRFYMYEILKALDYCH 148
           PN++ L ++ +    +   LVF++V++T   +L    + L +  ++  +Y+ L A+++CH
Sbjct: 241 PNLVRLIEVFRR--KKRLHLVFDYVDHTLLNELDRYPRGLPEPMVKRIIYQTLLAVNFCH 414

Query: 149 SMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYH-PGQEYNVRVASRYFKGPELLVDYQ 207
               +HRDVKP N++I  +  +++L D+G A     PG EY   VA+R+++ PELLV   
Sbjct: 415 QYNTIHRDVKPENILITRQG-QVKLCDFGFARILTGPGDEYTDYVATRWYRAPELLVGDT 591

Query: 208 MYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLG 250
            Y   +D+W++GC+ A ++   +  + G  + DQL  I K LG
Sbjct: 592 QYGPPVDVWAIGCVFAELL-TGQALWPGRSDVDQLHLIRKTLG 717
>04591
          Length = 1117

 Score = 92.8 bits (229), Expect = 2e-19,   Method: Compositional matrix adjust.
 Identities = 78/296 (26%), Positives = 134/296 (45%), Gaps = 10/296 (3%)
 Frame = -2

Query: 93   NIITLADIV---KDPVSR---TPALVFEHVNNTDFKQLYQTL----TDYDIRFYMYEILK 142
            N++ L +I      P +R   T  L+FE+ +  D   L   L    +  D +  M ++L 
Sbjct: 1038 NVVQLQEICHTQAGPYNRYKSTFYLIFEYCD-YDLAGLLNNLRVKFSLADKKNLMSQLLN 862

Query: 143  ALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPEL 202
             L Y H+  I+HRD+K  N+++  +   L+L D+GL+  +   +    RV + +++ PEL
Sbjct: 861  GLFYIHTKQILHRDIKAANILLTRDG-VLKLADFGLSRPWVKSKRLTNRVVTLWYRPPEL 685

Query: 203  LVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYN 262
            L+  + Y   +DMW +GC++A M  RK P   G     QL  I  + G+ +   +     
Sbjct: 684  LLGEREYGPEIDMWGVGCIMAEMWSRK-PLMQGRSEQHQLSLITDLCGSLNAEVWPGVTK 508

Query: 263  IELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHP 322
            +EL  + +   G+  RK  ER +      L + E  + +D  LR D   R+    A+ H 
Sbjct: 507  LELYGKLDLPQGK-PRKVKERML----DLLKNKEGAELIDIFLRLDPGQRMNCDNALSHD 343

Query: 323  YFYTVVKDQARMSSTSMAGGSTPVSSANMMSGISSVPTPSPLGPLAGSPVIAAANS 378
            +F+                   P+ S ++ S +S++P    LG +   P     NS
Sbjct: 342  FFWV-----------------DPLPSPSLTSILSNLPPMHELGVVRRPPARNPQNS 226
>32000
          Length = 644

 Score = 86.7 bits (213), Expect = 2e-17,   Method: Compositional matrix adjust.
 Identities = 56/173 (32%), Positives = 87/173 (50%), Gaps = 3/173 (1%)
 Frame = -1

Query: 170 KLRLIDWGLAE-FYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFR 228
           K+++ D+GLA  F  P + Y   V + +++ PE+L+  + Y   +D+WSLGC+   M+ R
Sbjct: 575 KMKIADFGLARVFGLPVRTYTHEVITLWYRAPEILLGCRFYSVPVDIWSLGCIFVEMMTR 396

Query: 229 KEPFFHGHDNYDQLVRIAKVLGTED--LYDYIDKYNIELDPRFNDILGRHSRKRWERFVH 286
           +   F G    DQL RI + LGT D  ++  + K      P +     +   K  E  V 
Sbjct: 395 RA-LFPGDSEIDQLYRIFRTLGTPDEKVWPGVSKL-----PDYKPTFPKWPLKNLETVVS 234

Query: 287 SENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTVVKDQARMSSTSM 339
                 +S   LD L ++L Y+   R++AR AM HPYF     D  RM+ T +
Sbjct: 233 ------LSKVGLDLLKRMLTYNPNRRISARSAMRHPYF----NDMKRMT*TDL 105
>04138
          Length = 800

 Score = 86.7 bits (213), Expect = 2e-17,   Method: Compositional matrix adjust.
 Identities = 57/201 (28%), Positives = 103/201 (51%), Gaps = 6/201 (2%)
 Frame = +1

Query: 144 LDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPG----QEYNVRVASRYFKG 199
           L Y H   I+HRD+K  N++I  +   L+L D+GLA  +         Y  RV + +++ 
Sbjct: 52  LYYIHRNKILHRDMKAANILITKQG-VLKLADFGLARAFSVNLRQPNRYTNRVVTLWYRP 228

Query: 200 PELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLG--TEDLYDY 257
           PELL+  + Y  ++D W  GC++A M + + P   G    +QL  I ++ G  T +++  
Sbjct: 229 PELLLGDRNYSTAIDQWGAGCIMAEM-WTRNPIMQGTTEQNQLTLITQLCGSITPEVWPG 405

Query: 258 IDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTARE 317
           + + ++    +     GR +  R +RF     + L  P  LD  ++LL+ D   R++A E
Sbjct: 406 VTQLSMYHQIKGALAAGRKNIIR-DRFA----RILKDPYGLDLFERLLKMDPSQRISADE 570

Query: 318 AMEHPYFYTVVKDQARMSSTS 338
           A+ H +F+  V+ ++ +   S
Sbjct: 571 ALNHDFFWVGVEPKSLVGVLS 633
>29581
          Length = 1278

 Score = 85.1 bits (209), Expect = 4e-17,   Method: Compositional matrix adjust.
 Identities = 69/255 (27%), Positives = 124/255 (48%), Gaps = 15/255 (5%)
 Frame = -2

Query: 85   LENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTL----TDYDIRFYMYEI 140
            L NLR   NI+ L ++V      +  LV E+    D   L   +    ++  ++  + ++
Sbjct: 1193 LLNLRHQ-NIVQLQEVVVGKSLDSLFLVMEYCEQ-DLASLLDNMPAPFSESQVKCIVLQL 1020

Query: 141  LKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFY-HPGQEYNVRVASRYFKG 199
            LK L Y H   I+HRD+K  N+++  +   +++ D+GLA  Y  P +    +V + +++ 
Sbjct: 1019 LKGLRYLHEAFIIHRDLKVSNLLMT-DKGCVKIADFGLARNYGKPQKPMTPKVVTLWYRA 843

Query: 200  PELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYI- 258
            PELL   + +  ++DMWS GC+L  ++  K P   G  +  Q+  I ++LGT +  D I 
Sbjct: 842  PELLFGSKTHSTAIDMWSAGCILGELLGHK-PLMPGRSDLQQIELIMELLGTPN--DTIW 672

Query: 259  ---------DKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDH 309
                     +++ ++  P +N++  RH+   W           +S   +  L+ L  Y  
Sbjct: 671  PGFSQLPAFEQFTLKKQP-YNNL--RHTFP-W-----------LSESGIRLLNGLFMYHP 537

Query: 310  QSRLTAREAMEHPYF 324
            Q R TA + +EH YF
Sbjct: 536  QKRATAEDCLEHSYF 492
>01756
          Length = 1858

 Score = 76.3 bits (186), Expect = 2e-14,   Method: Compositional matrix adjust.
 Identities = 65/264 (24%), Positives = 113/264 (42%), Gaps = 19/264 (7%)
 Frame = -3

Query: 7    SRARVYTDVNTHRPREYWDYESHVVEWGNQD-DYQLVRKLGRGKYSEVFEAINITNNEXX 65
            SR R   D   + P     YE+    + ++D  Y+ + K+G+G + EVF+A      +  
Sbjct: 1820 SREREQKDSQRYSP-----YETLKFPFCDEDAKYEKLAKIGQGTFGEVFKARCKKTKQVV 1656

Query: 66   XXXXXXXXXXXXXXXXXXXLE----NLRGGPNIITLADIVKDPVSRTPA------LVFEH 115
                                E     L    N++ L +I     +          LVFE 
Sbjct: 1655 AMKKVLMDNEKEGFPITALREIKILQLLNHENVVDLIEICSTKATSANRYKSMFYLVFEF 1476

Query: 116  VNNTDFKQLYQTLTDY----DIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKL 171
              + D   L   ++      +I+  M +++  L Y H   I+HRD+K  N++I  +   L
Sbjct: 1475 CEH-DLAGLLSNMSVVFNLPEIKEVMKQLMNGLYYIHRNKILHRDMKAANILITKQG-VL 1302

Query: 172  RLIDWGLAEFYHPG----QEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIF 227
            +L D+GLA  +         Y  RV + +++ PELL+  + Y  ++D W  GC++A M +
Sbjct: 1301 KLADFGLARAFSVNLRQPNRYTNRVVTLWYRPPELLLGDRNYSTAIDQWGAGCIMAEM-W 1125

Query: 228  RKEPFFHGHDNYDQLVRIAKVLGT 251
             + P   G    +QL  I ++ G+
Sbjct: 1124 TRNPIMQGTTEQNQLTLITQLCGS 1053
>21079
          Length = 878

 Score = 76.3 bits (186), Expect = 2e-14,   Method: Compositional matrix adjust.
 Identities = 44/133 (33%), Positives = 74/133 (55%), Gaps = 5/133 (3%)
 Frame = +1

Query: 92  PNIITLADIVKDPVSRTPALVFEHVNNTD-FKQLYQ---TLTDYDIRFYMYEILKALDYC 147
           P ++ L D  + P  RT  LV E V   + F+++ +    LT+ D   ++ +I   + Y 
Sbjct: 4   PKLLMLWDAFEAP--RTMVLVMEFVGAGELFERVIRDDFVLTERDCVHFVRQICSGVGYM 177

Query: 148 HSMGIMHRDVKPHNVM-IDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDY 206
           H+  I+H D+KP NV+ +     ++++ID+GLA FY PG    V   +  F  PE +V+Y
Sbjct: 178 HTQSILHLDLKPENVLCVSDNSNQIKIIDFGLARFYKPGDSLQVLFGTPEFIAPE-VVNY 354

Query: 207 QMYDYSLDMWSLG 219
              +++ DMWS+G
Sbjct: 355 DEINFTTDMWSIG 393
>15910
          Length = 1361

 Score = 72.0 bits (175), Expect = 3e-13,   Method: Compositional matrix adjust.
 Identities = 56/211 (26%), Positives = 93/211 (44%), Gaps = 2/211 (0%)
 Frame = +2

Query: 129 TDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMID--HEHRKLRLIDWGLAEFYHPGQ 186
           T+ D    + +IL  + Y H+ G++HRD+KP N++ +   +  KL+L D+GL+    P  
Sbjct: 458 TEKDAARAISDILHGVQYIHANGVVHRDLKPENLLYECMTDDSKLKLADFGLSRIIEPEV 637

Query: 187 EYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIA 246
           + +    +  +  PE+L   + Y  S+DMWS+G +   ++   EPFF  ++         
Sbjct: 638 QMSTVCGTPGYCAPEVLKGDK-YTPSVDMWSVGVIAYILLCGYEPFFAENEF-------- 790

Query: 247 KVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLR 306
                 ++Y  I K   + D  +           W           +S  A D + KLL 
Sbjct: 791 ------EMYRKIIKGEYKFDEEY-----------WSE---------ISENAKDVVRKLLV 892

Query: 307 YDHQSRLTAREAMEHPYFYTVVKDQARMSST 337
            D + RLTA EA+  P+   V      M  T
Sbjct: 893 IDPKKRLTATEALRLPWVKGVATKTTNMEIT 985
>26560
          Length = 398

 Score = 68.6 bits (166), Expect = 4e-12,   Method: Compositional matrix adjust.
 Identities = 36/106 (33%), Positives = 63/106 (59%)
 Frame = -1

Query: 127 TLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQ 186
             T+ ++RFY  E++  L++ HS  +++RD+KP N+++D E+  +R+ D GLA  +   +
Sbjct: 368 VFTEKEVRFYAAEVMLGLEHMHSRFVVYRDLKPANILLD-ENGHVRISDLGLACDFSKKR 192

Query: 187 EYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPF 232
            +   V +  +  PE+L+  Q YD S D +S GCML  ++    PF
Sbjct: 191 PH-ASVGTHGYMAPEVLMKGQSYDSSADWFSFGCMLYKLLKGHSPF 57
>23319
          Length = 2235

 Score = 68.6 bits (166), Expect = 4e-12,   Method: Compositional matrix adjust.
 Identities = 42/120 (35%), Positives = 60/120 (50%), Gaps = 2/120 (1%)
 Frame = +3

Query: 207 QMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLG--TEDLYDYIDKYNIE 264
           +MY  S+DMWS GC+ A +     P F G+D+ DQL RI K+LG  TED +  + +    
Sbjct: 21  KMYSTSIDMWSAGCIFAELANAGRPLFPGNDDDDQLKRIFKLLGTPTEDQWPGMTQL--- 191

Query: 265 LDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYF 324
             P +      H    W++ V   N      +  D L  LL      R++A EA++HPYF
Sbjct: 192 --PNYRMFPMYHVTTTWQQVVPKLNS-----KGRDLLQCLLVCCPSDRMSADEALQHPYF 350
>00300
          Length = 2318

 Score = 62.0 bits (149), Expect = 4e-10,   Method: Compositional matrix adjust.
 Identities = 53/226 (23%), Positives = 104/226 (46%), Gaps = 18/226 (7%)
 Frame = -1

Query: 39   YQLVRKLGRGKYSEVFEAINITNNEXXXXXXXXXXXXXXXXXXXXXLENLRGGPNIITLA 98
            +Q   K+G G++ +V+ A+N++  E                     L+ LR   + I + 
Sbjct: 1652 WQRGNKIGEGQFGKVYTAVNMSTGELMALKEMKFQPND--------LQQLREMCDEIKIF 1497

Query: 99   DIVKDP---------VSRTPALVF-EHVNNTDFKQLYQT-LTDYDIRFYMYEILKALDYC 147
            + ++           V +   L+F E+ +    ++  +  L +Y IR Y  EI+ A+++ 
Sbjct: 1496 EGIQHENLVKYYGVEVHKDEMLMFMEYCDTGTIEEAAKMGLPEYLIRRYTREIVLAVNHL 1317

Query: 148  HSMGIMHRDVKPHNVMIDHEHRKLRLIDWGL-----AEFYHPGQEYNVRVASRYFKGPEL 202
            H   I+HRD+K  N+ +   +  ++L D+G      +    PG+ +N+ V +  +  PE+
Sbjct: 1316 HENSIVHRDIKGANIFLT-SNGHVKLGDFGCSVKLKSHTTMPGEFHNL-VGTTAYMAPEV 1143

Query: 203  LV--DYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIA 246
                D   Y  + D+WSLGC++  M   K P+    +NY  + ++ 
Sbjct: 1142 FTQNDQGGYGRAADIWSLGCVVIEMATGKRPWHDLDNNYQIMYKVG 1005
>13212
          Length = 1067

 Score = 61.6 bits (148), Expect = 5e-10,   Method: Compositional matrix adjust.
 Identities = 53/208 (25%), Positives = 89/208 (42%), Gaps = 7/208 (3%)
 Frame = -1

Query: 124  LYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVM--IDHEHRKLRLIDWGL-AE 180
            L + +T+  I +  +E+  ALD+ H   ++HRD+K  NV+  ID E   ++L D+G+ A+
Sbjct: 1001 LEKPMTEAQICYVCHEMCMALDFLHRHHVIHRDIKAGNVLLTIDGE---VKLADFGVSAK 831

Query: 181  FYHPGQEYNVRVASRYFKGPELLVDYQM----YDYSLDMWSLGCMLASMIFRKEPFFHGH 236
                 Q+ +  + + Y+  PE+++   +    YD+  D+WSLG  L      + P    H
Sbjct: 830  NTQTQQKRDTFIGTPYWMAPEVVLCETLKDTPYDFKADIWSLGVTLIEFAQIEPPNKEMH 651

Query: 237  DNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPE 296
                 L++I K                      +D       K+W +             
Sbjct: 650  -PMRVLIKIHK----------------------SDPPTLEKPKKWTKLFK---------- 570

Query: 297  ALDFLDKLLRYDHQSRLTAREAMEHPYF 324
              DF+ K L  D   R TA E +EHP+ 
Sbjct: 569  --DFIAKCLVKDPNLRPTAAELLEHPFM 492
>12786
          Length = 460

 Score = 61.2 bits (147), Expect = 6e-10,   Method: Compositional matrix adjust.
 Identities = 43/142 (30%), Positives = 72/142 (50%), Gaps = 22/142 (15%)
 Frame = -3

Query: 126 QTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPG 185
           Q L    I+FY  E+L+A+   H+ G++H D+KP N M+   +  L+LID+G+A      
Sbjct: 425 QGLDRMMIKFYWREMLRAVKALHNEGVIHSDLKPANFMLVAGN--LKLIDFGIANTLQQD 252

Query: 186 QE---YNVRVASRYFKGPELLV-------DYQMYD--------YSL----DMWSLGCMLA 223
           +     + RV +  +  PE ++       D  M +        Y +    D+WSLGC+L 
Sbjct: 251 KTSVLKDSRVGTPSYMSPEAIMAACDDSADDSMEEDGHRTKPKYKVGVRSDVWSLGCILY 72

Query: 224 SMIFRKEPFFHGHDNYDQLVRI 245
           +M++ + PF H  +N  +L  I
Sbjct: 71  NMVYGRTPFQHIKNNMGKLQAI 6
>12721
          Length = 821

 Score = 61.2 bits (147), Expect = 6e-10,   Method: Compositional matrix adjust.
 Identities = 33/95 (34%), Positives = 57/95 (60%), Gaps = 1/95 (1%)
 Frame = +1

Query: 141 LKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGL-AEFYHPGQEYNVRVASRYFKG 199
           LKAL + H+ G++HRD+K  ++++ H+  K++L D+G  A+     Q+    V + Y+  
Sbjct: 403 LKALAFLHANGVIHRDIKSDSILLSHDG-KVKLXDFGFCAQVTQDLQKRKSLVGTPYWMA 579

Query: 200 PELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFH 234
           PE++     Y   +D+WSLG M+  MI  + PFF+
Sbjct: 580 PEVISRLP-YGPEVDIWSLGIMVMEMIDAEPPFFN 681
>01392
          Length = 1806

 Score = 60.8 bits (146), Expect = 9e-10,   Method: Compositional matrix adjust.
 Identities = 56/211 (26%), Positives = 88/211 (41%), Gaps = 12/211 (5%)
 Frame = -1

Query: 128  LTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDH--EHRKLRLIDWGLAEFYH-- 183
            L + +    +  I +ALD+ HS GI HRD+KP N++ +H  +   +++ D+ LA      
Sbjct: 1800 LCEREASLVVRHIARALDFLHSKGIAHRDLKPENILCEHLDDVVPVKICDFDLASGISCD 1621

Query: 184  ----PGQEYNVRVASRYFKGPEL----LVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHG 235
                   E    V S  +  PE+    + D   YD   D+WSLG +L  M+    PF   
Sbjct: 1620 GDGTKTPELLTPVGSAEYMAPEVVDAWVGDSFSYDKRCDLWSLGIILYIMLCGYPPF--- 1450

Query: 236  HDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSP 295
               Y Q          E  +D  D         FN I   H +        S+    +S 
Sbjct: 1449 ---YGQCGEDCGWNRGEACHDCQDML-------FNSIQDGHYK------FPSQEWTSISS 1318

Query: 296  EALDFLDKLLRYDHQSRLTAREAMEHPYFYT 326
             A D +  LL  + + R +A + ++HP+  T
Sbjct: 1317 SAKDLIRHLLVREPRKRYSAADVLKHPWICT 1225
>30755
          Length = 1137

 Score = 60.5 bits (145), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 39/125 (31%), Positives = 66/125 (52%), Gaps = 2/125 (1%)
 Frame = +2

Query: 126 QTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLA-EFYHP 184
           +  T+   RFY  EI+ AL Y HS GI++RD+K  N+++D +   +++ D+GL  E    
Sbjct: 17  RIFTEERTRFYGAEIISALGYLHSQGIIYRDLKLENLLLDKDGH-IKVADFGLCKEDITY 193

Query: 185 GQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFH-GHDNYDQLV 243
           G+       +  +  PE+L D   Y  ++D W  G ++  MI  + PF++  HD    L+
Sbjct: 194 GRTTKTFCGTPEYLAPEVLDDND-YGRAVDWWGTGVVMYEMICGRLPFYNRDHDVLFTLI 370

Query: 244 RIAKV 248
            +  V
Sbjct: 371 LVEDV 385
>28638
          Length = 1458

 Score = 60.5 bits (145), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 28/77 (36%), Positives = 49/77 (63%), Gaps = 1/77 (1%)
 Frame = -1

Query: 150 MGIMHRDVKPHNVMIDHEHRK-LRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQM 208
           M I+H D+KP N+++ +  R  ++++D+G +     GQ     + SR+++ PE+L+    
Sbjct: 774 MNIIHCDLKPENILLCNPKRSAIKIVDFGSS--CQLGQRIYQYIQSRFYRSPEVLLGVP- 604

Query: 209 YDYSLDMWSLGCMLASM 225
           YD ++DMWSLGC+L  M
Sbjct: 603 YDLAIDMWSLGCILVEM 553

 Score = 33.1 bits (74), Expect = 0.20,   Method: Compositional matrix adjust.
 Identities = 32/141 (22%), Positives = 60/141 (42%), Gaps = 32/141 (22%)
 Frame = -2

Query: 216 WSLGCMLASMIFRK----EPFFHGHDNYDQLVRIAKVLG------------TEDLYDYI- 258
           W L C   ++ + +     P F G + +DQ+++I +VLG            T   +D + 
Sbjct: 596 WPLTCGXWAVYWWRCTXGNPLFAGSNEFDQMMKIVEVLGVPPRHILDQAQKTRKYFDLLP 417

Query: 259 ------------DKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLR 306
                        KY      + +++LG        R +  E  H V+ + L F D +LR
Sbjct: 416 DGTYAPKKPRDNKKYKSPSSRKLHEVLGAEKGGPGGRRM-GEPGHTVA-DYLKFKDLILR 243

Query: 307 ---YDHQSRLTAREAMEHPYF 324
              +D ++R++   A++H +F
Sbjct: 242 MLDFDPKTRISPYYALQHNFF 180
>01966
          Length = 1735

 Score = 60.5 bits (145), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 37/136 (27%), Positives = 72/136 (52%), Gaps = 7/136 (5%)
 Frame = -1

Query: 93   NIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQ------TLTDYDIRFYMYEILKALDY 146
            NI+ L D++ +       LVFE ++  D K           L    ++ Y+++I+  +++
Sbjct: 1531 NIVCLEDVIME--DERLFLVFEFLS-MDLKMYIDKFPEGVVLDRRLVKSYVFQIVTGINF 1361

Query: 147  CHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAE-FYHPGQEYNVRVASRYFKGPELLVD 205
            CH   I+HRD+KP N++I+H    +++ D+G+A  F  P + Y   V + +++ PE+L+ 
Sbjct: 1360 CHQRRIVHRDLKPQNLLINHTG-AIKIADFGMARTFALPVRAYTHEVVTLWYRAPEILMG 1184

Query: 206  YQMYDYSLDMWSLGCM 221
             Q    +   W+ G +
Sbjct: 1183 PQ---STPPXWTCGAL 1145

 Score = 56.6 bits (135), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 32/119 (26%), Positives = 58/119 (48%)
 Frame = -3

Query: 209  YDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPR 268
            Y   +D+WS+G + A M+ R  P F G    DQL +I +++GT     + + + +   P 
Sbjct: 1175 YSTPVDVWSIGTIFADMLIRT-PIFKGDSEIDQLFKIFRIIGTPTEQTWPEFHKL---PA 1008

Query: 269  FNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTV 327
            FN +        W+    SE    +    LD +++ L+ D   R++ ++ ++H YF  V
Sbjct: 1007 FNGMF-----PLWKEGKLSETLTDLDSLGLDLIERTLKCDPAQRISCKKMLQHAYFLNV 846
>14420
          Length = 528

 Score = 57.4 bits (137), Expect = 9e-09,   Method: Compositional matrix adjust.
 Identities = 30/97 (30%), Positives = 55/97 (56%), Gaps = 1/97 (1%)
 Frame = +2

Query: 139 EILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQ-EYNVRVASRYF 197
           E L+AL++ H   ++HRD+K  N+++  +   ++L D+G      P Q + +  V + Y+
Sbjct: 221 ECLQALEFLHENQVIHRDIKSDNILLGMDG-SVKLTDFGFCAQLSPEQSKRSTMVGTPYW 397

Query: 198 KGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFH 234
             PE++   Q Y  ++D+WSLG M   MI  + P+ +
Sbjct: 398 MAPEVVTRKQ-YGPTVDIWSLGVMCIEMIEGEPPYLN 505
>27405
          Length = 532

 Score = 56.6 bits (135), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 35/128 (27%), Positives = 67/128 (52%), Gaps = 3/128 (2%)
 Frame = -3

Query: 90  GGPNIITLADIVKDPVSRTPALVFEHVNNTDFK---QLYQTLTDYDIRFYMYEILKALDY 146
           G P I+ +    + P       + + +N  D       +   T+ ++RFY  E++  L++
Sbjct: 380 GSPFIVCMTYAFQTP--EKLCFILDLMNGGDLHYHLSQHGVFTEKEVRFYAAEVMLGLEH 207

Query: 147 CHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDY 206
            HS  +++RD+KP N+++D E+  +R+ D GLA  +   ++ +  V +  +  PE+L+  
Sbjct: 206 MHSRFVVYRDLKPANILLD-ENGHVRISDLGLACDFSK-KKPHASVGTHGYMAPEVLMKG 33

Query: 207 QMYDYSLD 214
           Q YD S D
Sbjct: 32  QAYDSSAD 9
>18921
          Length = 697

 Score = 56.6 bits (135), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 34/110 (30%), Positives = 57/110 (51%), Gaps = 1/110 (0%)
 Frame = +2

Query: 126 QTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLA-EFYHP 184
           +TL + +I   +Y  LK L Y HS   +HRD+K  N+++++E    +L D+G+A +    
Sbjct: 302 KTLVEREIATILYYTLKGLXYLHSRRKIHRDIKAGNILLNNEGHA-KLADFGVAGQLTDT 478

Query: 185 GQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFH 234
             + N  + + Y+  PE++ +   YD   D+WSLG     M   K P   
Sbjct: 479 MAKRNTVIGTPYWMAPEVIQEIG-YDCVADIWSLGITALEMAEGKPPVME 625
>18287
          Length = 678

 Score = 56.2 bits (134), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 45/169 (26%), Positives = 77/169 (45%), Gaps = 6/169 (3%)
 Frame = -3

Query: 209 YDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGT---EDLYDYIDKYNIEL 265
           YDYS+D+WS+GC+ A ++ R+   F       QL  I  ++GT   ED+    +      
Sbjct: 673 YDYSIDIWSVGCIFAELLSRRI-LFQAQGPVQQLDMIINLVGTPRPEDMERACEGAR--- 506

Query: 266 DPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFY 325
               N IL +  R++    +++ + H  + EA+  L ++L  + ++R++A EA+ HPY  
Sbjct: 505 ----NHILNQPFRRQNLLTLYNLSPH-ATHEAVRLLTRMLILNPKNRISAEEALSHPYL- 344

Query: 326 TVVKDQARMS-STSMAGGSTPVSSA--NMMSGISSVPTPSPLGPLAGSP 371
               D+ R+   + M     PV      +       P   PL P    P
Sbjct: 343 ----DEGRVRFHSCMCSCCKPVPGMGRQLCPDTQWEPCCPPLQPQLRQP 209
>31885
          Length = 529

 Score = 55.5 bits (132), Expect = 4e-08,   Method: Compositional matrix adjust.
 Identities = 29/104 (27%), Positives = 55/104 (52%), Gaps = 4/104 (3%)
 Frame = -2

Query: 133 IRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRV 192
           ++FY+ ++   LDY  S  I+HRD+KP N+++D E     + D+ +A      +      
Sbjct: 366 VKFYLCQLALVLDYLRSQKIVHRDIKPDNILLD-EQGHCHVTDFNIATQLEDDELATSTS 190

Query: 193 ASRYFKGPEL----LVDYQMYDYSLDMWSLGCMLASMIFRKEPF 232
            +R +  PE+    + + + Y + +D WSLG  L  ++ ++ PF
Sbjct: 189 GTRPYMAPEVYGVAINERRGYGFPVDWWSLGVSLFELLKKRRPF 58
>03294
          Length = 1684

 Score = 55.1 bits (131), Expect = 5e-08,   Method: Compositional matrix adjust.
 Identities = 31/117 (26%), Positives = 58/117 (49%)
 Frame = -1

Query: 211  YSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFN 270
            + +D+WS+G + A M+ R  P F G    DQL +I +++GT     + + + +   P FN
Sbjct: 1678 HPVDVWSIGTIFADMLIRT-PIFKGDSEIDQLFKIFRIIGTPTEQTWPEFHKL---PAFN 1511

Query: 271  DILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTV 327
             +        W+    SE    +    LD +++ L+ D   R++ ++ ++H YF  V
Sbjct: 1510 GMF-----PLWKEGKLSETLTDLDSLGLDLIERTLKCDPAQRISCKKMLQHAYFLNV 1355
>19761
          Length = 473

 Score = 55.1 bits (131), Expect = 5e-08,   Method: Compositional matrix adjust.
 Identities = 38/125 (30%), Positives = 62/125 (49%), Gaps = 3/125 (2%)
 Frame = -3

Query: 133 IRFYMYEILKALDYCHSMG--IMHRDVKPHNVMIDHEHRKLRLIDWGLA-EFYHPGQEYN 189
           I  ++ +   AL+Y H+    I+HRD+KP N+ +  E   +RL D GLA +   P     
Sbjct: 417 IVCWLMQTASALNYMHTHTPVILHRDLKPQNIYVT-EKGDVRLGDLGLARKLTGPADFAT 241

Query: 190 VRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVL 249
            +V +  +  PE+L   Q Y+   D+WSLGC+   +  +K     G D    +  + +V+
Sbjct: 240 SQVGTIMYLSPEIL-SQQPYNSKSDIWSLGCVFYDITGKK-----GSDEMGVMFLLVQVM 79

Query: 250 GTEDL 254
           G   L
Sbjct: 78  GGRKL 64
>26711
          Length = 405

 Score = 55.1 bits (131), Expect = 5e-08,   Method: Compositional matrix adjust.
 Identities = 28/95 (29%), Positives = 53/95 (55%), Gaps = 1/95 (1%)
 Frame = -2

Query: 139 EILKALDYCHSMGIMHRDVKPHNVMIDHEH-RKLRLIDWGLAEFYHPGQEYNVRVASRYF 197
           ++L  L + H+ G++H D+KP N+++  +    ++LID+GLA   +P QE  +   +  F
Sbjct: 392 QVLDILQHVHAQGVVHMDLKPSNLLLSGDKLDSVQLIDFGLARKLYPPQETFLNHGTPGF 213

Query: 198 KGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPF 232
             PE L D +    + D+W +G +   ++  + PF
Sbjct: 212 TSPEAL-DVKPISTASDVWGVGVLAYILLSGQSPF 111
>18484
          Length = 635

 Score = 54.7 bits (130), Expect = 6e-08,   Method: Compositional matrix adjust.
 Identities = 35/104 (33%), Positives = 55/104 (52%), Gaps = 6/104 (5%)
 Frame = +1

Query: 135 FYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVAS 194
           FY  EI   L + H  GI++RD+K  NVM+D E   +++ D+G+ +    G        +
Sbjct: 55  FYAAEIAVGLFFLHDQGIIYRDLKLDNVMLDSEGH-IKIADFGMCKEGMTGD-----ATT 216

Query: 195 RYFKG------PELLVDYQMYDYSLDMWSLGCMLASMIFRKEPF 232
           R F G      PE+++ YQ Y  S+D W+ G +L  M+  + PF
Sbjct: 217 RTFCGTPDYIAPEIVL-YQPYSKSVDWWAYGVLLFEMLAGQPPF 345
>09606
          Length = 1300

 Score = 54.3 bits (129), Expect = 9e-08,   Method: Compositional matrix adjust.
 Identities = 54/222 (24%), Positives = 91/222 (40%), Gaps = 25/222 (11%)
 Frame = -3

Query: 128 LTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAE------- 180
           L +  IR +   ++  L Y HS+GI+  D++P  V++D     L+  D+GL++       
Sbjct: 842 LPETSIRDFGIHLVTGLHYIHSLGILFHDLRPSKVLLD-TSGVLKFADFGLSKVEGENLE 666

Query: 181 -----FYHPGQEYNVRVASRYFK-----------GPELLVDYQMYDYSL--DMWSLGCML 222
                F   G ++N++ A    K            PE+   +Q  + S+  D+W+LGC+ 
Sbjct: 665 ELFFKFAEAGDQWNIQSAEEMMKQVPTSGSPTYMAPEV---FQGAEPSIMSDLWALGCVF 495

Query: 223 ASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWE 282
             M F   P F G + YD  +   KVL  E     +    +   P               
Sbjct: 494 YEM-FSGHPPFLG-ETYD--ITKDKVLNKEFPLPKVKGSRLSAKP--------------- 372

Query: 283 RFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYF 324
                      SPE L+ L+ LL+ D   RL+    ++H ++
Sbjct: 371 -----------SPEFLNLLESLLQKDSTRRLSWASLVKHAFW 279
>19094
          Length = 898

 Score = 53.9 bits (128), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 32/101 (31%), Positives = 55/101 (54%), Gaps = 1/101 (0%)
 Frame = +1

Query: 126 QTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLA-EFYHP 184
           +TL + +I   +Y  LK L Y HS   +HRD+K  N+++++E    +L D+G+A +    
Sbjct: 43  KTLVEREIATILYYTLKGL*YLHSRRKIHRDIKAGNILLNNEGHA-KLADFGVAGQLTDT 219

Query: 185 GQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASM 225
             + N  + + Y+  PE++ +   YD   D+WSLG     M
Sbjct: 220 MAKRNTVIGTPYWMAPEVIQEIG-YDCVADIWSLGITALEM 339
>13592
          Length = 980

 Score = 53.1 bits (126), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 63/295 (21%), Positives = 113/295 (38%), Gaps = 15/295 (5%)
 Frame = +2

Query: 44  KLGRGKYSEVFEAINITNNEXXXXXXXXXX--XXXXXXXXXXXLENLRG--GPNIITLAD 99
           K+G+G++ +V+ A+N    E                       L+ L G    N++    
Sbjct: 5   KIGQGRFGKVYTAVNNNTGELMAMKEIAIQPGETRALKNVAEELKILEGIKHKNLVRYYG 184

Query: 100 IVKDPVSRTPALVFEHVNNT----DFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHR 155
           I    V R   L+F  + +        +L   L +   R +  ++L  +   H  GI+HR
Sbjct: 185 I---EVHREELLIFMELCSEGTLESLVELTGGLPEALSRRFTAQLLSGVAELHKHGIVHR 355

Query: 156 DVKPHNVMIDHEHRKLRLIDWGLAEFYH-----PGQEYNVRVASRYFKGPELLVDYQMYD 210
           D+K  N+ +      L+L D+G A         PG E    V ++ +  PE+        
Sbjct: 356 DIKTANIFLVDGSNSLKLGDFGSAVKIQAHTTVPG-ELQGYVGTQAYMAPEVFTKTNSDG 532

Query: 211 YS--LDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPR 268
           +    D+WS+GC++  M   K P+     N+  + ++   +G +              P+
Sbjct: 533 HGRLADIWSVGCVVVEMASGKRPWAQFDSNFQIMFKVG--MGEK--------------PQ 664

Query: 269 FNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPY 323
             + L                    S E  DF+D  L++D + RL+A E +E  +
Sbjct: 665 APESL--------------------SQEGHDFIDHCLQHDPKQRLSAIELLEQNF 769
>18401
          Length = 463

 Score = 50.4 bits (119), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 35/143 (24%), Positives = 75/143 (52%), Gaps = 10/143 (6%)
 Frame = -3

Query: 192 VASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGT 251
           V++R+++ PE++++   + +  D+WS+GC++   ++     F  HDN + L  + ++LG+
Sbjct: 449 VSTRHYRAPEVILELG-WSHPCDVWSVGCIMFE-LYTGYTLFQTHDNKEHLAMMERILGS 276

Query: 252 EDLYDYIDK-------YNIELDPRFNDILGRHSRKRWE---RFVHSENQHLVSPEALDFL 301
              Y    K       ++  LD      + R+ R+  +   R+V  + ++    +  D +
Sbjct: 275 LP-YRMAKKTKKQKYFHHGRLDVPERSSMARYVRENTKPLLRYV-KDRENKDHQQLFDLM 102

Query: 302 DKLLRYDHQSRLTAREAMEHPYF 324
            KLL Y+  SR +  +A++HP+F
Sbjct: 101 KKLLAYEASSRYSLLQALQHPFF 33
>03240
          Length = 1683

 Score = 49.3 bits (116), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 36/145 (24%), Positives = 57/145 (39%), Gaps = 45/145 (31%)
 Frame = -3

Query: 134 RFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGL--------------- 178
           RFY+ E+++A++  H MG +HRD+KP N++ID     ++L D+GL               
Sbjct: 982 RFYVAELVQAIESVHRMGFIHRDIKPDNILIDRNGH-IKLTDFGLCTGFRWTHNSKYYQR 806

Query: 179 ---------------------AEFYHPGQEYNVR---------VASRYFKGPELLVDYQM 208
                                 E   P +    R         V +  +  PE+L     
Sbjct: 805 DGTHARQDSMEVKCQLDEQCQCEILKPLERRRKREQRCLAHSLVGTPNYIAPEVLSRLGG 626

Query: 209 YDYSLDMWSLGCMLASMIFRKEPFF 233
           Y    D WS+G +L  M+    PF+
Sbjct: 625 YTSVCDWWSVGVILFEMLVGHPPFY 551
>21433
          Length = 590

 Score = 48.9 bits (115), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 27/97 (27%), Positives = 53/97 (54%)
 Frame = +2

Query: 136 YMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASR 195
           Y+Y++  AL+YCH   ++HRD+KP N+++      L++ D+G +  + P         + 
Sbjct: 182 YIYQLSSALEYCHYRKVIHRDIKPENLLLG-LKGDLKIADFGWS-VHAPSSRRTTMCGTL 355

Query: 196 YFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPF 232
            +  PE +V+ + +D ++D+WSLG +    +    P 
Sbjct: 356 DYLPPE-MVEGKTHDENVDLWSLGVLCYEFLVGTPPL 463
>13078
          Length = 773

 Score = 48.5 bits (114), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 37/126 (29%), Positives = 61/126 (48%), Gaps = 14/126 (11%)
 Frame = -1

Query: 213 LDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDK-------YNIEL 265
            D+WS+GC++   ++     F  HDN + L  + ++LG+   Y    K       Y+  L
Sbjct: 734 CDVWSIGCIMFE-LYTGYTLFQTHDNKEHLAMMERILGSLP-YRMAKKTKKQKYFYHGRL 561

Query: 266 DPRFNDILGRHSR---KRWERFV----HSENQHLVSPEALDFLDKLLRYDHQSRLTAREA 318
           D       GR+ R   K   R+V    + ++Q L      D +DK+L Y+  +R + R+A
Sbjct: 560 DWDEKSSAGRYVRDNVKPLRRYVKDPDNEDHQQL-----FDLMDKMLSYEVSTRYSLRQA 396

Query: 319 MEHPYF 324
           M HP+F
Sbjct: 395 MRHPFF 378
>31489
          Length = 329

 Score = 47.8 bits (112), Expect = 9e-06,   Method: Compositional matrix adjust.
 Identities = 27/77 (35%), Positives = 49/77 (63%), Gaps = 6/77 (7%)
 Frame = +3

Query: 93  NIITLADIVKDPVS----RTPALVFEHVNNTDFKQLY--QTLTDYDIRFYMYEILKALDY 146
           NII++ +I+K   S    +   +VF+ + +   + +Y  Q LT+  IR+++Y+IL+ L Y
Sbjct: 33  NIISIREILKPKDSYHDFKDIHVVFDLMESDLHRIIYSDQPLTEEHIRYFLYQILRGLKY 212

Query: 147 CHSMGIMHRDVKPHNVM 163
            HS  ++HRD+KP N++
Sbjct: 213 IHSANVVHRDLKPSNLL 263
>04852
          Length = 1462

 Score = 46.2 bits (108), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 28/90 (31%), Positives = 46/90 (51%), Gaps = 3/90 (3%)
 Frame = +1

Query: 136 YMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASR 195
           Y ++I + +++  S   +HRD+   NV++  EH  L++ D+GL+     G  Y  R   R
Sbjct: 340 YAFQIARGMEFLASRKCIHRDLAARNVLVTEEH-VLKIADFGLS---RTGDYYKKRSGGR 507

Query: 196 Y---FKGPELLVDYQMYDYSLDMWSLGCML 222
               +  PE L D + Y    D+WS G +L
Sbjct: 508 LPVKWMAPEALFDMR-YTTKSDVWSFGVVL 594
>13066
          Length = 551

 Score = 46.2 bits (108), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 27/90 (30%), Positives = 45/90 (50%), Gaps = 4/90 (4%)
 Frame = +3

Query: 134 RFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGL--AEFYHPGQEYNVR 191
           + + Y++  AL+Y HS  + HRD+K  N+++   H  ++L D+G   A     G++Y  R
Sbjct: 285 KIWFYQMTTALNYLHSYDVAHRDLKCENILLS-SHFNVKLADFGFACACITESGEKYMSR 461

Query: 192 --VASRYFKGPELLVDYQMYDYSLDMWSLG 219
               S  +  PE++          D WSLG
Sbjct: 462 TYCGSAAYAAPEIVYGAPYAPKVADAWSLG 551
>07940
          Length = 1336

 Score = 45.8 bits (107), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 29/104 (27%), Positives = 50/104 (48%), Gaps = 3/104 (2%)
 Frame = -3

Query: 122 KQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEF 181
           + + + LT  D+  Y Y++ + ++Y  S   +HRD+   NV++  E+  L++ D+GL   
Sbjct: 374 QDMLKMLTPKDLISYAYQVARGMEYLASKQCIHRDLAARNVLVAEEY-VLKIADFGLTRN 198

Query: 182 YHPGQEYNVRVASRY---FKGPELLVDYQMYDYSLDMWSLGCML 222
                 Y      R    +  PE L D + Y    D+WS G +L
Sbjct: 197 LQQFDYYRKTTDGRLPVKWMAPEALFDRK-YTSKSDVWSYGVLL 69
>11185
          Length = 473

 Score = 44.7 bits (104), Expect = 7e-05,   Method: Compositional matrix adjust.
 Identities = 31/120 (25%), Positives = 55/120 (45%), Gaps = 25/120 (20%)
 Frame = +1

Query: 132 DIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAE----------- 180
            IR +   ++  L Y HS+GI+  D++P  V++D     L+  D+GL++           
Sbjct: 4   SIRDFGIHLVTGLHYIHSLGILFHDLRPSKVLLD-TSGVLKFADFGLSKVEGENLEELFF 180

Query: 181 -FYHPGQEYNVRVASRYFK-----------GPELLVDYQMYDYSL--DMWSLGCMLASMI 226
            F   G ++N++ A    K            PE+   +Q  + S+  D+W+LGC+   M 
Sbjct: 181 KFAEAGDQWNIQSAEEMMKQVPTSGSPTYMAPEV---FQGAEPSIMSDLWALGCVFYEMF 351
>00715
          Length = 1788

 Score = 43.9 bits (102), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 38/149 (25%), Positives = 63/149 (42%), Gaps = 27/149 (18%)
 Frame = +1

Query: 111 LVFEHVNNTDFKQL---YQTLTDYDIRFYM-YEILKALDYCHSMGIMHRDVKPHNVMIDH 166
           L  E+V   + + +   +Q   D  +R  +  ++ + L Y HS+ I+H D+KP N ++  
Sbjct: 166 LAMEYVGPLNLQTILNDHQQDIDSSMRLSLALQMARGLHYLHSINIVHLDLKPANCLLTR 345

Query: 167 EHRKLRLIDWGLAEFYHP-----------------------GQEYNVRVASRYFKGPELL 203
           +  KLR+ D+G      P                       G   N    +  ++ PELL
Sbjct: 346 D-LKLRIADFGCCHQLTPTGLDMGEREGGMAGNELELTPVQGAWKNELAGTLAYRAPELL 522

Query: 204 VDYQMYDYSLDMWSLGCMLASMIFRKEPF 232
              Q    S D++SLG  L  M  R+ P+
Sbjct: 523 KGLQPSVRS-DVYSLGITLWQMCTRQGPY 606
>17975
          Length = 449

 Score = 42.4 bits (98), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 16/44 (36%), Positives = 30/44 (68%)
 Frame = +3

Query: 136 YMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLA 179
           Y  +I++A+ YCH + ++HRD+KP NV+   +   ++L D+G +
Sbjct: 282 YFRQIVEAISYCHKLHVVHRDLKPENVVFFEKPGLVKLTDFGFS 413
>37602
          Length = 804

 Score = 40.8 bits (94), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 26/90 (28%), Positives = 40/90 (44%), Gaps = 3/90 (3%)
 Frame = -1

Query: 111 LVFEHVNNTDFKQLYQT---LTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHE 167
           +  E+      + +Y     LT+  I F   E LK L Y H  G MHRD+K  N+++  E
Sbjct: 288 IAMEYCGGGSMQDIYHVTGPLTEPQIAFVCRETLKGLHYLHRRGKMHRDIKGANILLTEE 109

Query: 168 HRKLRLIDWGLAEFYHPGQEYNVRVASRYF 197
                  D  LA+F+     ++  V  + F
Sbjct: 108 G------DVKLADFWRVSSNHSHNVQKKVF 37
>14116
          Length = 1017

 Score = 40.4 bits (93), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 26/102 (25%), Positives = 50/102 (49%), Gaps = 5/102 (4%)
 Frame = -1

Query: 132 DIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLA-----EFYHPGQ 186
           D+  Y  +I + +DY   +  +HRD+   N M+D E   +++ D+GLA     + Y+  +
Sbjct: 318 DLIMYGVDIARGMDYLAGLKFVHRDLAARNCMLD-EDFHVKVADFGLARDIYEKEYYSSE 142

Query: 187 EYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFR 228
               ++  ++     L  +   YD   D+WS G +L  ++ R
Sbjct: 141 NKKAKLPVKWMALESL--EKGNYDSKTDVWSYGVVLWELLTR 22
>01718
          Length = 959

 Score = 39.7 bits (91), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 49/218 (22%), Positives = 90/218 (41%), Gaps = 9/218 (4%)
 Frame = +3

Query: 20  PREYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEXXXXXXXXXXXXXXXX 79
           P+       H V    + D  +  K+G G +SEVF+  +    +                
Sbjct: 96  PKSSCQALRHAVSALTRLDDFICEKIGAGFFSEVFKVTHRITGQVMALKMNTMTSNRHNM 275

Query: 80  XXXXXLENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTD---YDIRFY 136
                L N     NI+    +      +  AL  E++ + + +QL +   +   +  R  
Sbjct: 276 LREVQLLNRLQHANILRFMGVCVHE-GQLHALT-EYIPSGNLEQLLEKKDEELPWTQRIQ 449

Query: 137 M-YEILKALDYCHSMGIMHRDVKPHNVMI---DHEHRKLRLIDWGLA-EFYHP-GQEYNV 190
           +   + + LDY HS   +HRD+   N++I   D+      + D+GLA +   P  +E   
Sbjct: 450 LTLGLARGLDYLHSTRFIHRDLTSKNILIRREDNHGYHAVIADFGLATKIPDPLDKEKLP 629

Query: 191 RVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFR 228
            V S Y+  PE+L +   Y+   D++S+G ++  +  R
Sbjct: 630 TVGSPYWMAPEVL-NGHFYNERADLFSVGIIMCEITAR 740
>01106
          Length = 878

 Score = 38.9 bits (89), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 38/163 (23%), Positives = 68/163 (41%), Gaps = 18/163 (11%)
 Frame = +3

Query: 20  PREYWDYESHVVEWGN--QDDYQLVRKLGRGKYSEV----------FEAINITNNEXXXX 67
           PR+Y     H V+ G+     Y ++RKLG G +S V          F A+ +  +     
Sbjct: 261 PRDYCKGGYHPVKNGDLFNGRYHVIRKLGWGHFSTVWLCWDLTCKRFVALKVVKSAQHYT 440

Query: 68  XXXXXXXXXXXXXXXXXLENLRGGPNIITLADIVKDPVSRT-PALVFEHVNNTDFKQL-- 124
                            + +      +  L D     V+ T  A+VFE +     K +  
Sbjct: 441 ETALDEVKLLKCVRESDVADPARAKCVQLLDDFKISGVNGTHVAMVFEVLGYNLLKLIIR 620

Query: 125 --YQTLTDYDIRFYMYEILKALDYCHSMG-IMHRDVKPHNVMI 164
             YQ +  ++++  + ++L+ L Y H+   I+H D+KP N++I
Sbjct: 621 SNYQGIPIHNVKLIIRQVLEGLSYMHAKCRIIHTDIKPENILI 749
>26009
          Length = 886

 Score = 38.9 bits (89), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 14/33 (42%), Positives = 24/33 (72%)
 Frame = +3

Query: 132 DIRFYMYEILKALDYCHSMGIMHRDVKPHNVMI 164
           + +  M +++ ALD+ HS  ++HRD+KP NV+I
Sbjct: 714 EAKSVMKQLVSALDFMHSKQLVHRDIKPENVLI 812
>05084
          Length = 1324

 Score = 38.5 bits (88), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 27/102 (26%), Positives = 44/102 (43%), Gaps = 2/102 (1%)
 Frame = +2

Query: 235 GHDNYDQLVRIAKVLGTEDLYDYIDKYNI-ELDPRFNDI-LGRHSRKRWERFVHSENQHL 292
           G    DQLV I KVLGT        +  I E++P +++    +     W +         
Sbjct: 8   GDSGVDQLVEIIKVLGTP------TREQIREMNPNYSEFKFPQIKAHPWTKVFRPRT--- 160

Query: 293 VSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTVVKDQARM 334
             PEA+  + +LL Y   +R+   EA  H +F  +    +R+
Sbjct: 161 -PPEAIQLVSRLLEYTPSARIQPMEACAHAFFDELRDPASRL 283
>06358
          Length = 1517

 Score = 38.1 bits (87), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 48/176 (27%), Positives = 84/176 (47%), Gaps = 31/176 (17%)
 Frame = +3

Query: 123 QLYQTLTDYDIRFYMYEILKALDYCHS-MGIMHRDVKPHNVMIDHEHRKLRLIDWGLA-- 179
           Q YQ L D +I+  + ++ +AL + H+   +MHR+V P  +M+       +L  W LA  
Sbjct: 339 QDYQ-LYDVEIKHGLLQVTEALGFLHNDAKMMHRNVCPEAIMLT------KLGSWKLAGY 497

Query: 180 EFY------------HPGQEYNVRVASRY-----FKGPELLVDYQMYDYSLDMWSLGCML 222
           EF             +P  E+   +A        F  PE ++  Q    S DM+SLG ++
Sbjct: 498 EFCVRSSDPQSTDPSYPFYEWRSDIAPVTQPHLDFMAPEYVLTMQCGTGS-DMFSLGLLV 674

Query: 223 ASMIFRKEPFFHGH-------DNYDQL--VRIAKVLGT--EDLYDYIDKYNIELDP 267
            S+  + +P F  +        N ++L  +R++ +LG   EDL D++ K  + ++P
Sbjct: 675 YSVFAKGKPLFECNGELSAFKSNAEELRHMRVS-LLGVVPEDLRDHV-KLLLNIEP 836
>00392
          Length = 668

 Score = 38.1 bits (87), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 25/93 (26%), Positives = 51/93 (54%), Gaps = 3/93 (3%)
 Frame = +3

Query: 133 IRFYMYEILKALDYCHSMG--IMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNV 190
           ++ +  ++LK L + H+    ++HRD+K  N+ I      +++ D GLA   +     +V
Sbjct: 252 LKNWCRQVLKGLYFLHTRTPPVIHRDLKCDNIFITGPTGSVKIGDLGLATLKNQSFAKSV 431

Query: 191 RVASRYFKGPELLVDYQMYDYSLDMWSLG-CML 222
            + +  F  PE+  ++  YD ++D+++ G CML
Sbjct: 432 -IGTPEFMAPEMYEEH--YDEAVDVYAFGMCML 521
>21800
          Length = 855

 Score = 37.4 bits (85), Expect = 0.012,   Method: Compositional matrix adjust.
 Identities = 24/86 (27%), Positives = 45/86 (52%), Gaps = 10/86 (11%)
 Frame = +2

Query: 110 ALVFEHVNNTDFKQL----YQTLTDYDIRFYMYEILKALDYCHS-MGIMHRDVKPHNVMI 164
            +VFE +     K +    YQ +  ++++  + ++L+ L+Y H+   I+H D+KP N++I
Sbjct: 557 CMVFEVLGYNLLKLIIRSNYQGIPVHNVKLIIRQVLEGLNYLHAKCNIIHTDIKPENILI 736

Query: 165 ---DHEHRKLRL--IDWGLAEFYHPG 185
              D+  RKL +   +W       PG
Sbjct: 737 CVDDNYIRKLAVDAFEWQRLGLKLPG 814
>32359
          Length = 928

 Score = 28.5 bits (62), Expect(2) = 0.020,   Method: Compositional matrix adjust.
 Identities = 9/17 (52%), Positives = 14/17 (82%)
 Frame = -3

Query: 151 GIMHRDVKPHNVMIDHE 167
           G+ HRD+KP N+++D E
Sbjct: 65  GVCHRDIKPQNLLLDPE 15

 Score = 26.6 bits (57), Expect(2) = 0.020,   Method: Compositional matrix adjust.
 Identities = 15/49 (30%), Positives = 26/49 (53%), Gaps = 6/49 (12%)
 Frame = -1

Query: 111 LVFEHVNNTDFK------QLYQTLTDYDIRFYMYEILKALDYCHSMGIM 153
           LV E+V  T ++      +  QT+    I+ YMY++ ++L Y HS   +
Sbjct: 202 LVLEYVPETVYRVARHYSKSKQTIPILYIKLYMYQLFRSLAYIHSQACV 56
>27546
          Length = 426

 Score = 35.8 bits (81), Expect = 0.030,   Method: Compositional matrix adjust.
 Identities = 15/48 (31%), Positives = 30/48 (62%)
 Frame = -1

Query: 134 RFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEF 181
           + + +++ KAL Y HS  I HRD+K  N+++  +   +++ D+G A +
Sbjct: 171 KVWFFQMAKALQYLHSHDIAHRDLKCENILLS-KRLNVKIADFGFARY 31
>02638
          Length = 1490

 Score = 35.4 bits (80), Expect = 0.039,   Method: Compositional matrix adjust.
 Identities = 31/128 (24%), Positives = 52/128 (40%)
 Frame = +1

Query: 197 FKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYD 256
           F  PE+L   + Y  + D+WS+GC++  M   + P ++ HD  + L  I K+  +     
Sbjct: 34  FMAPEVLRG-ESYGRACDVWSVGCVMIEMCTCRPP-WNSHDISNHLALIFKIASS----- 192

Query: 257 YIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAR 316
            +D   I                        EN   +SP   D + + L  D   R +A+
Sbjct: 193 -VDPPPI-----------------------PEN---MSPPVRDLMLRCLEQDSDFRPSAK 291

Query: 317 EAMEHPYF 324
           + + HP F
Sbjct: 292 DLLMHPLF 315
>18481
          Length = 437

 Score = 35.0 bits (79), Expect = 0.053,   Method: Compositional matrix adjust.
 Identities = 19/51 (37%), Positives = 31/51 (60%), Gaps = 3/51 (5%)
 Frame = -1

Query: 139 EILKALDYCHSMGIMHRDVKPHNVMID---HEHRKLRLIDWGLAEFYHPGQ 186
           ++L  L++ H    +HRD+KP N ++    H HR L +ID+GL++ Y   Q
Sbjct: 173 QLLSRLEFIHQKCFIHRDLKPDNFLMGLGRHCHR-LYIIDFGLSKRYKDTQ 24
>28157
          Length = 400

 Score = 34.7 bits (78), Expect = 0.066,   Method: Compositional matrix adjust.
 Identities = 29/105 (27%), Positives = 46/105 (43%), Gaps = 13/105 (12%)
 Frame = +3

Query: 92  PNIITLADIVKD-PVSRTPALVFEHVNNTDFKQLYQTL---------TDYDIRFYMYEIL 141
           PNI+ L    +D PV     LV E+        LY  L         T      ++ +  
Sbjct: 90  PNIVCLYGACRDHPV----CLVMEYAEGGS---LYNVLHGSGPQPQYTAAHAMNWLLQCA 248

Query: 142 KALDYCHSM---GIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYH 183
             ++Y H M    ++HRD+KP N+++     KL++ D+G A   H
Sbjct: 249 LGVEYLHGMKPKALIHRDLKPPNLLLIQCGTKLKICDFGTACDIH 383
>29360
          Length = 363

 Score = 34.3 bits (77), Expect = 0.079,   Method: Composition-based stats.
 Identities = 21/66 (31%), Positives = 33/66 (50%), Gaps = 14/66 (21%)
 Frame = +3

Query: 113 FEHVNNT--DFKQLYQTLTDY------------DIRFYMYEILKALDYCHSMGIMHRDVK 158
           F+H N+T   F+ L Q L D+             IR    ++L AL     +G++H D+K
Sbjct: 162 FQHKNHTCLVFEMLEQNLYDFLKQNKFQPLPLKYIRPITQQVLTALRKLKQLGLIHADLK 341

Query: 159 PHNVMI 164
           P N+M+
Sbjct: 342 PENIML 359
>15931
          Length = 447

 Score = 33.5 bits (75), Expect = 0.13,   Method: Compositional matrix adjust.
 Identities = 12/29 (41%), Positives = 20/29 (68%)
 Frame = +1

Query: 296 EALDFLDKLLRYDHQSRLTAREAMEHPYF 324
           +  D +DK+L Y+  +R + R+AM HP+F
Sbjct: 70  QLFDLMDKMLSYEVSTRYSLRQAMRHPFF 156
>19301
          Length = 712

 Score = 33.5 bits (75), Expect = 0.16,   Method: Compositional matrix adjust.
 Identities = 27/105 (25%), Positives = 53/105 (50%), Gaps = 10/105 (9%)
 Frame = +2

Query: 85  LENLR--GGPNIITLADIVKDPVSRTPA--LVFEHVNNTDFKQLYQTLTDYD------IR 134
           + NLR    PNII+   +     ++ P   ++ E+     + QLY+ L D        + 
Sbjct: 422 IRNLRKLNHPNIISFKGVC----TQAPCYCIIMEYC---PYGQLYEVLRDGKEIPPALVL 580

Query: 135 FYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLA 179
            +  +I   ++Y HS  I+HRD+K  NV++  ++  +++ D+G +
Sbjct: 581 DWSKQIASGMNYLHSHKIIHRDLKSPNVLV-AKNDVVKISDFGTS 712
>11801
          Length = 743

 Score = 33.1 bits (74), Expect = 0.20,   Method: Compositional matrix adjust.
 Identities = 23/82 (28%), Positives = 42/82 (51%), Gaps = 3/82 (3%)
 Frame = -1

Query: 226 IFRKEPFFHGHDNYDQLVR---IAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWE 282
           + +K P       YDQL R   +AKV+       + D++ I+LDP+++  + ++S  +  
Sbjct: 272 LLKKFPVTSSSIPYDQLQRRCSVAKVVSETSCCKFGDQF-IKLDPQYDYRVAKYSYLQSY 96

Query: 283 RFVHSENQHLVSPEALDFLDKL 304
           R+     QH+   +AL F D +
Sbjct: 95  RYFDDHKQHIR--QALMFNDTI 36
>26909
          Length = 394

 Score = 33.1 bits (74), Expect = 0.22,   Method: Compositional matrix adjust.
 Identities = 29/109 (26%), Positives = 43/109 (39%), Gaps = 10/109 (9%)
 Frame = +2

Query: 226 IFRKEPFFHGHD---------NYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRH 276
           +   EP FH            ++DQL RI  V+G     D+ D   +    +      R 
Sbjct: 14  LLTSEPIFHCRQEDIKTSNPYHHDQLDRIFNVMGFPQEKDWEDIRRMPEHQQLTKDFKRS 193

Query: 277 SRKRWERFVHSENQHL-VSPEALDFLDKLLRYDHQSRLTAREAMEHPYF 324
           S        + E   +    +A   L KLL  D   R+T+ +AM+ PYF
Sbjct: 194 SYVNCNLMKYMEKHKVKADSKAFHLLQKLLTMDPVKRITSEQAMKDPYF 340
>29590
          Length = 320

 Score = 32.7 bits (73), Expect = 0.24,   Method: Composition-based stats.
 Identities = 18/58 (31%), Positives = 28/58 (48%)
 Frame = +3

Query: 175 DWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPF 232
           D G A   + G++    + +  +  PE+L DY+      DMWSLG +   M+    PF
Sbjct: 6   DLGFACLTNTGEDIRDIIGTPDYVAPEVL-DYEPLSIQTDMWSLGVLSYVMLTACSPF 176
>14104
          Length = 573

 Score = 32.7 bits (73), Expect = 0.26,   Method: Compositional matrix adjust.
 Identities = 11/32 (34%), Positives = 19/32 (59%)
 Frame = +1

Query: 293 VSPEALDFLDKLLRYDHQSRLTAREAMEHPYF 324
            +P+A+ F+   L+ D   RLT  + ++HPY 
Sbjct: 88  AAPQAMSFMQSCLKMDPAERLTCHQLLQHPYM 183
>12672
          Length = 773

 Score = 30.8 bits (68), Expect = 0.98,   Method: Compositional matrix adjust.
 Identities = 23/91 (25%), Positives = 43/91 (47%), Gaps = 7/91 (7%)
 Frame = +3

Query: 143 ALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPG-----QEYNVRVASRYF 197
            + Y +  G +HRD+K  N+++D E+   ++ D+        G     Q  +V + +  +
Sbjct: 27  GIQYLNDNGHVHRDIKTANILLDSEYTA-KVGDFATVVSAPSGEGKTVQNASVVIGTAAY 203

Query: 198 KGPELLVDYQMYDYS--LDMWSLGCMLASMI 226
             PE +     +D S  LD +S G +L  +I
Sbjct: 204 LAPEAI----HFDVSTKLDSYSFGVVLLEVI 284
>27274
          Length = 396

 Score = 30.4 bits (67), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 30/126 (23%), Positives = 50/126 (39%)
 Frame = -1

Query: 199 GPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYI 258
           G ELL   Q +  ++DMWSLG +L  ++    PF        Q+ R    +         
Sbjct: 381 GAELLRG-QQHGPTVDMWSLGILLHELLSGHVPF-EPERGSRQMARNMMAV--------- 235

Query: 259 DKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREA 318
                     +  I+   SR   +          +S    DFL +L++ +   RLT+++A
Sbjct: 234 ----------YAQIIRGSSRDVCDGLA-------LSTHGADFLRRLVQLEDTKRLTSQQA 106

Query: 319 MEHPYF 324
             HP+ 
Sbjct: 105 FSHPWI 88
>35032
          Length = 465

 Score = 30.4 bits (67), Expect = 1.4,   Method: Compositional matrix adjust.
 Identities = 12/27 (44%), Positives = 16/27 (59%)
 Frame = +3

Query: 299 DFLDKLLRYDHQSRLTAREAMEHPYFY 325
           D + +LL YD   RLT   A+ HP+ Y
Sbjct: 147 DLVKRLLNYDPSKRLTPXXALAHPFLY 227
>37063
          Length = 455

 Score = 30.0 bits (66), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 25/79 (31%), Positives = 37/79 (46%), Gaps = 13/79 (16%)
 Frame = -2

Query: 157 VKPHNVMIDH--EHRKLRLIDWGLAEFYHPGQ------EYNVRVASRYFKGPELLVDYQM 208
           +KP N++ +H  E   L++ D+ LA   +         E    V S  +  PE+ VD  +
Sbjct: 454 LKPENILCEHLDEVVPLKICDFDLASGINCDGDGTKTPELLTPVGSAEYMAPEV-VDAWV 278

Query: 209 -----YDYSLDMWSLGCML 222
                YD   DMWSLG +L
Sbjct: 277 GESFSYDKRCDMWSLGIIL 221
>17932
          Length = 597

 Score = 30.0 bits (66), Expect = 1.8,   Method: Compositional matrix adjust.
 Identities = 17/35 (48%), Positives = 22/35 (62%)
 Frame = -3

Query: 293 VSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTV 327
           VS EA D + +LL  D +SRL   E  +HP+F TV
Sbjct: 460 VSKEARDLISQLLS-DGKSRLGWPELQQHPFFKTV 359
>16350
          Length = 1108

 Score = 29.6 bits (65), Expect = 2.0,   Method: Compositional matrix adjust.
 Identities = 10/26 (38%), Positives = 18/26 (69%)
 Frame = +3

Query: 299 DFLDKLLRYDHQSRLTAREAMEHPYF 324
           DFL  +L +D + R TA ++++HP+ 
Sbjct: 762 DFLAPMLEFDPEQRATAAQSLQHPWL 839
>20513
          Length = 405

 Score = 28.9 bits (63), Expect = 3.3,   Method: Compositional matrix adjust.
 Identities = 10/26 (38%), Positives = 18/26 (69%)
 Frame = -1

Query: 299 DFLDKLLRYDHQSRLTAREAMEHPYF 324
           DFL  +L +D + R TA ++++HP+ 
Sbjct: 282 DFLAPMLEFDPEQRATAAQSLQHPWL 205
>18663
          Length = 600

 Score = 28.9 bits (63), Expect = 4.0,   Method: Compositional matrix adjust.
 Identities = 13/34 (38%), Positives = 21/34 (61%)
 Frame = +2

Query: 199 GPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPF 232
            PE+L   + Y +S+D W+LG +L  M+  + PF
Sbjct: 32  APEILRG-EDYGFSVDWWALGVLLYEMLAGRSPF 130
>20773
          Length = 391

 Score = 28.5 bits (62), Expect = 5.2,   Method: Compositional matrix adjust.
 Identities = 16/50 (32%), Positives = 25/50 (50%)
 Frame = -1

Query: 274 GRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPY 323
           G H R+    F H+    +V+    + + +LL YD   RLT   A+ HP+
Sbjct: 370 GLHRRRSRPVFPHTT---VVTQHFYNLVQRLLTYDPSQRLTPDLALSHPF 230
>28419
          Length = 687

 Score = 28.1 bits (61), Expect = 6.3,   Method: Compositional matrix adjust.
 Identities = 22/77 (28%), Positives = 37/77 (48%), Gaps = 5/77 (6%)
 Frame = +3

Query: 140 ILKALDYCHSMG----IMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASR 195
           ILK L YC ++      ++   K  N+    EH K++ +  G     +      +R  S+
Sbjct: 342 ILKRLRYCLNLSKPPSYLNTVRKL*NISYVREHDKVKALMLGFKLLVNSQCANALRHPSQ 521

Query: 196 YFKGPELL-VDYQMYDY 211
             KGPEL+  D+Q Y++
Sbjct: 522 I*KGPELIPYDFQFYEF 572
>20152
          Length = 445

 Score = 27.7 bits (60), Expect = 9.2,   Method: Compositional matrix adjust.
 Identities = 12/39 (30%), Positives = 23/39 (58%)
 Frame = +1

Query: 200 PELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDN 238
           PE+L+       ++D+WSLG +L  ++  + PF   +D+
Sbjct: 1   PEILLGDSYDAPAVDVWSLGVILYMLVVGEAPFQEANDS 117
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31981273|ref|NP_075638.2| CNDP dipeptidase 2 [Mus
musculus]
         (475 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

33994                                                                 360   e-113
>33994
          Length = 933

 Score =  360 bits (925), Expect(2) = e-113,   Method: Compositional matrix adjust.
 Identities = 169/240 (70%), Positives = 203/240 (84%)
 Frame = +1

Query: 234 GSVHEAMTDLISLMGCLVDKKGKILIPGINDAVAPVTDEEHALYDHIDFDMEEFAKDVGA 293
           G+VHEAM D+I+LM  LVD KGKIL+PG+ D+V P+TDEE ALYD I+FDM ++ KD+GA
Sbjct: 94  GTVHEAMGDVIALMNSLVDVKGKILVPGVCDSVKPLTDEEKALYDPIEFDMGDYQKDIGA 273

Query: 294 ETLLHSCKKDILMHRWRYPSLSLHGIEGAFSGSGAKTVIPRKVVGKFSIRLVPDMIPEVV 353
           + L+H  K+D+LMHRWRYPSLSLHGIEGAFSGSGAKTVIPRKV+GKFSIRLVPD  P  +
Sbjct: 274 KKLIHDKKEDVLMHRWRYPSLSLHGIEGAFSGSGAKTVIPRKVIGKFSIRLVPDQEPSEI 453

Query: 354 SEQVSSYLSKKFAELQSPNKFKVYMGHGGKPWVSDFNHPHYQAGRRALKTVFGVEPDLTR 413
            + V  ++ K  AE  SPNK  + MGHGG+PWVSDFNHP+Y AGR A+K VF +EPDLTR
Sbjct: 454 EKHVRQHVEKVHAERGSPNKITLSMGHGGRPWVSDFNHPNYMAGRAAMKRVFKMEPDLTR 633

Query: 414 EGGSIPVTLTFQEATGKNVMLLPVGSADDGAHSQNEKLNRLNYIEGTKMLAAYLYEVSQL 473
           EGGSIPVTLTFQEATGKNVMLLP+GS DDGAHSQNEK+NR NYI+G K+LAAY+ E++++
Sbjct: 634 EGGSIPVTLTFQEATGKNVMLLPIGSCDDGAHSQNEKINRSNYIQGVKLLAAYMEELAKV 813

 Score = 65.5 bits (158), Expect(2) = e-113,   Method: Compositional matrix adjust.
 Identities = 27/31 (87%), Positives = 30/31 (96%)
 Frame = +2

Query: 203 KPCITYGLRGICYFFIEVECSDKDLHSGVYG 233
           KPCITYGLRGICYFF+EVEC+D DLHSGV+G
Sbjct: 2   KPCITYGLRGICYFFLEVECADMDLHSGVFG 94
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|62234487|ref|NP_080758.1| plasma membrane calcium
ATPase 1 [Mus musculus]
         (1220 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

12151                                                                 277   e-113
06342                                                                 234   2e-61
29829                                                                 222   9e-58
00499                                                                 212   6e-55
35407                                                                 146   6e-35
21541                                                                 138   2e-32
36566                                                                 127   2e-29
08160                                                                  65   1e-10
14773                                                                  62   2e-09
28890                                                                  54   3e-07
04985                                                                  52   2e-06
13525                                                                  43   8e-04
33697                                                                  39   0.010
14321                                                                  39   0.016
07486                                                                  38   0.021
21117                                                                  30   4.5  
>12151
          Length = 880

 Score =  277 bits (708), Expect(2) = e-113,   Method: Compositional matrix adjust.
 Identities = 146/198 (73%), Positives = 166/198 (83%), Gaps = 4/198 (2%)
 Frame = +3

Query: 806 KKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNVV 865
           +KADVGFAMGI+GTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSI+KFLQFQLTVNVV
Sbjct: 288 QKADVGFAMGISGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSIAKFLQFQLTVNVV 467

Query: 866 AVIVAFTGACITQDSPLKAVQMLWVNLIMDTLASLALATEPPTESLLLRKPYGRNKPLIS 925
           AV VAF GAC   DSPLKA+QMLWVNLIMDTLASLALATE P+  LL R+PYGR KPLIS
Sbjct: 468 AVFVAFVGACSIGDSPLKAIQMLWVNLIMDTLASLALATELPSSELLKRRPYGRTKPLIS 647

Query: 926 RTMMKNILGHAFYQLVVVFTLLFAGEK-FFDID---SGRNAPLHAPPSEHYTIVFNTFVL 981
           +TM KNILGHAFYQ++V+  LLF G K  +D     + R  P   P ++H+TI+FN FV+
Sbjct: 648 KTMWKNILGHAFYQILVILLLLFQGAKAVWDRRWHPTSRETP--RPTNQHFTIIFNAFVM 821

Query: 982 MQLFNEINARKIHGERNV 999
           M LFNE+NARKIH +RN+
Sbjct: 822 MTLFNEVNARKIHDQRNI 875

 Score =  152 bits (383), Expect(2) = e-113,   Method: Compositional matrix adjust.
 Identities = 70/98 (71%), Positives = 85/98 (86%)
 Frame = +1

Query: 710 DNINTARAIATKCGILHPGEDFLCLEGKDFNRRIRNEKGEIEQERIDKIWPKLRVLARSS 769
           DN+NTAR+IA+KCGI+ PG+D L LEGK+FN+ IR+ +GEI QE++D++WP LRVLARSS
Sbjct: 1   DNVNTARSIASKCGIIQPGDDGLVLEGKEFNQLIRDAEGEISQEKVDEVWPNLRVLARSS 180

Query: 770 PTDKHTLVKGIIDSTVSEQRQVVAVTGDGTNDGPALKK 807
           P DK+ LVK IIDS VS  R+VVAVTGDGTNDGPALKK
Sbjct: 181 PQDKYILVKHIIDSKVSTSREVVAVTGDGTNDGPALKK 294
>06342
          Length = 2428

 Score =  234 bits (597), Expect = 2e-61,   Method: Compositional matrix adjust.
 Identities = 195/624 (31%), Positives = 302/624 (48%), Gaps = 54/624 (8%)
 Frame = +2

Query: 356 KKEKSVLQGKLTKLAVQIGKAGLLMSAITVIILVLYFV-IDTFWVQKRPWLAECTPIYIQ 414
           ++EK+ LQ KL + + Q+ K       IT+I + ++ + I  F     P        +I+
Sbjct: 299 EQEKTPLQQKLDEFSNQLSKV------ITIICIAVWAINIGHF---NDPAHGGS---WIK 442

Query: 415 YFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICS 474
             + +F I V + V A+PEGLP  +T  LA   ++M K N +VR L + ET+G  + ICS
Sbjct: 443 GAIYYFKIAVALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICS 622

Query: 475 DKTGTLTMNRMTVVQAYI-----------------------------NEKHYKKVPEPEA 505
           DKTGTLT N+M+V + +I                             N K  K    P  
Sbjct: 623 DKTGTLTTNQMSVCKLFIFSQIDTNQIKTTQFEVTGSTYAPDGELYQNGKKVKASDYPGL 802

Query: 506 IPPNILSYLVTGISVNCAYTSKILPPEKEGGLPRHVGNKTECALLGFLLDL--------- 556
                +  +    SV+  Y       EK       VG  TE AL      L         
Sbjct: 803 EELCTICGMCNDSSVD--YNEAKTQYEK-------VGEATETALTVLAEKLNFYNTDKSS 955

Query: 557 --KRDYQDVRNEIPEEALYKVYT--FNSVRKSMSTVL-----KNSDGSFRIFSKGASEII 607
             KR+   V N + ++   K +T  F+  RKSMS            G  R+F+KGA E +
Sbjct: 956 LNKREMGTVCNHVIQDMWRKEFTLEFSRDRKSMSVFCVPNKPTRVPGGARMFAKGAPEGL 1135

Query: 608 LKKCFKILSANGEAKVFRPRDRDDIVK-TVIEPMASEGLRTICLAFRDFPAGEPEPEWDN 666
           L +C  +   N +  +  P  +++I+K T I     + LR + LA  D P    + + ++
Sbjct: 1136LDRCTHVRIGNNKVPM-SPAIKNEIMKLTKIYGTGRDTLRCLALATIDNPPRREDMDLED 1312

Query: 667 ENDVV---TGLTCIAVVGIEDPVRPEVPEAIKKCQRAGITVRMVTGDNINTARAIATKCG 723
               +   T +T + VVG+ DP R EV  +IK C+ AGI V ++TGDN  TA AI  + G
Sbjct: 1313SRKFIEYETNMTFVGVVGMLDPPREEVMASIKNCRAAGIRVIVITGDNKATAEAICRRIG 1492

Query: 724 ILHPGEDF--LCLEGKDFNRRIRNEKGEIEQERIDKIWPKLRVLARSSPTDKHTLVKGII 781
           +    E+   L   G++F+        E+  E       + R+ AR  P  K  +V+   
Sbjct: 1493VFSESENTEGLAYTGREFD--------ELPPEDQRAAVMRARLFARVEPAHKSKIVE--- 1639

Query: 782 DSTVSEQRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKA 841
              +  + ++ A+TGDG ND PALKKA++G AMG +GT VAK AS+++L DDNF++IV A
Sbjct: 1640--YLQAEGEISAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKSASEMVLADDNFSTIVAA 1810

Query: 842 VMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTLASLA 901
           V  GR +Y+++ +F+++ ++ N+  V+  F  A +     L  VQ+LWVNL+ D   + A
Sbjct: 1811VEEGRAIYNNMKQFIRYLISSNIGEVVCIFLTAALGIPEALIPVQLLWVNLVTDGFPATA 1990

Query: 902 LATEPPTESLLLRKPYGRNKPLIS 925
           L   PP   ++ + P    + LI+
Sbjct: 1991LGFNPPDLDIMQKPPRNPREGLIT 2062

 Score = 35.4 bits (80), Expect = 0.15,   Method: Compositional matrix adjust.
 Identities = 29/88 (32%), Positives = 40/88 (45%), Gaps = 13/88 (14%)
 Frame = +2

Query: 213 GDIAQVKYGDLLPAD-GIL-IQGNDLKIDESSLTGES-----------DHVXXXXXXXXX 259
           GDI +V  GD +PAD  IL I    L+ID++ LTGES           D           
Sbjct: 14  GDIVEVSVGDKVPADIRILKIHSTTLRIDQAILTGESVSVMKHTDPIPDPRAVNQDKKNL 193

Query: 260 XXXGTHVMEGSGRMVVTAVGVNSQTGII 287
              GT+V  G  + +V   G+ ++ G I
Sbjct: 194 LFSGTNVAAGKCKGLVIGTGLTTEIGKI 277
>29829
          Length = 465

 Score =  222 bits (565), Expect = 9e-58,   Method: Compositional matrix adjust.
 Identities = 115/150 (76%), Positives = 128/150 (85%)
 Frame = -3

Query: 810 VGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIV 869
           +GFAMGI+GTDVAKEASDIILTDDNFTSIVKAV WGRNVYDSI+KFLQFQLTVNVVAV V
Sbjct: 460 LGFAMGISGTDVAKEASDIILTDDNFTSIVKAVXWGRNVYDSIAKFLQFQLTVNVVAVFV 281

Query: 870 AFTGACITQDSPLKAVQMLWVNLIMDTLASLALATEPPTESLLLRKPYGRNKPLISRTMM 929
           AF GAC   DSPL+A+QMLWVNLIMDTLASLALATE P+  LL RKPYGR KPLIS+TM 
Sbjct: 280 AFVGACSIGDSPLEAIQMLWVNLIMDTLASLALATELPSNELLKRKPYGRTKPLISKTMF 101

Query: 930 KNILGHAFYQLVVVFTLLFAGEKFFDIDSG 959
           KNI GH+ YQ++++  +LF G   F ID G
Sbjct: 100 KNIAGHSVYQIIIILVILFKGADLFGIDDG 11
>00499
          Length = 4026

 Score =  212 bits (540), Expect = 6e-55,   Method: Compositional matrix adjust.
 Identities = 178/554 (32%), Positives = 276/554 (49%), Gaps = 44/554 (7%)
 Frame = +2

Query: 434 GLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTMNRMTVVQAYIN 493
           GL   VT+ L  + K+M + N LV++L+A ET+G+ + ICSDKTGTLT NRMTV   + +
Sbjct: 2   GLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFD 181

Query: 494 EKHYKKVPEPEAI-------PPNILSYLVTGISVNCAYTSKILPPEKEGGLPRHV-GNKT 545
            +  +     +          P  ++  ++ +++ C         +    L R   G+ +
Sbjct: 182 GRIVEADTSDDQSNATYSRSDPTWMA--LSRVAMLCNRAEFKGNQDNVPILKRECNGDAS 355

Query: 546 ECALL-------GFLLDLKRDYQDVRNEIPEEALYKVYTFNSVRKSMSTVLKNSDGS--- 595
           E ALL       G + + +R  + +  EIP         FNS  K   ++ +  D     
Sbjct: 356 ESALLKCVELSIGHVTEYRRRNEKIV-EIP---------FNSSNKYQVSIHETEDPDDPR 505

Query: 596 FRIFSKGASEIILKKCFKILSANGEAKVFRPRDRDDIVKTVIEPMASEGLRTICLAFRDF 655
           + +  KGA E I+ +C  IL  NG+ +      R+      +E     GL    L F D+
Sbjct: 506 YLLVMKGAPERIMDRCSTIL-LNGKEQPLDDNFREAFNAAYLE---LGGLGERVLGFCDY 673

Query: 656 --------PAGEPEPEWDNENDVVTGLTCIAVVGIEDPVRPEVPEAIKKCQRAGITVRMV 707
                   P  E +PE    N  +TGL  + ++ + DP R  VP+A+ KC+ AGI V MV
Sbjct: 674 FLPVDQFPPGYEFDPE--GPNFPITGLRFVGLMAMIDPPRAAVPDAVGKCRSAGIKVIMV 847

Query: 708 TGDNINTARAIATKCGILHPG----EDFLCLEGKDFNRRIRNEK-------GEIEQERID 756
           TGD+  TA+AIA   GI+  G    ED     G         E        G++      
Sbjct: 848 TGDHPITAKAIARGVGIISEGSKTVEDIASERGIPVEEVDPREAKAAVIHGGDLRDMTPA 1027

Query: 757 KIWPKLR-----VLARSSPTDKHTLVKGIIDSTVSEQRQVVAVTGDGTNDGPALKKADVG 811
           +I   LR     V AR+SP  K  +V+G        Q Q+VAVTGDG ND PALKKAD+G
Sbjct: 1028QIDEILRNHSEIVFARTSPQQKLIIVEG-----CQRQGQIVAVTGDGVNDSPALKKADIG 1192

Query: 812 FAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNV--VAVIV 869
            AMGIAG+DV+K+A+D+IL DDNF SIV  V  GR ++D++ K + + LT N+  ++  +
Sbjct: 1193VAMGIAGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEISPFL 1372

Query: 870 AFTGACITQDSPLKAVQMLWVNLIMDTLASLALATEPPTESLLLRKPYGRNKPLISRTMM 929
            F  A I    PL  + +L ++L  D + +++LA E     ++ R+P     P+  + + 
Sbjct: 1373LFILADIPL--PLGTITILCIDLGTDMVPAISLAYEKAENDIMKRQP---RDPVKDKLVN 1537

Query: 930 KNILGHAFYQLVVV 943
           + ++  A+ Q+ ++
Sbjct: 1538ERLISMAYGQIGMI 1579
>35407
          Length = 562

 Score =  146 bits (368), Expect = 6e-35,   Method: Compositional matrix adjust.
 Identities = 94/179 (52%), Positives = 111/179 (62%), Gaps = 8/179 (4%)
 Frame = +1

Query: 47  RKIQESYGDVY---GICTKLKTSPNEGLSGNPADLERREAVFGKNFIPPKKPKTFLQLVW 103
           R +Q     V+   G   KLKTSP EGL G+    E R   +G N IPPK PK+FL+LVW
Sbjct: 37  RGLQHHRHQVWRRPGNVQKLKTSPTEGLVGDLGK-EERVRFYGSNVIPPKPPKSFLRLVW 213

Query: 104 EALQDVTLIILEIAAIVSLGLSFYQPPEGDNALCXXXXXXXXXXXXXXXXXXXAAI---- 159
           EALQDVTL+IL +AAI+SLGLSFY+   GD                         I    
Sbjct: 214 EALQDVTLLILIVAAIISLGLSFYK---GDEEEDETEDESYRAKADSSLEEKVGWIDGLA 384

Query: 160 -LLSVVCVVLVTAFNDWSKEKQFRGLQSRIEQEQKFTVIRGGQVIQIPVADITVGDIAQ 217
            L++V  VVLVTAFNDWSKEKQFRGLQS+IE E +FTVIR G++ QIPV DI VG+I Q
Sbjct: 385 ILVAVAVVVLVTAFNDWSKEKQFRGLQSKIEHEHRFTVIRDGELHQIPVGDILVGEICQ 561
>21541
          Length = 445

 Score =  138 bits (347), Expect = 2e-32,   Method: Compositional matrix adjust.
 Identities = 72/124 (58%), Positives = 83/124 (66%)
 Frame = +3

Query: 170 TAFNDWSKEKQFRGLQSRIEQEQKFTVIRGGQVIQIPVADITVGDIAQVKYGDLLPADGI 229
           TAFNDWSKEKQFRGLQS+IE E +FTVIR G++ QIPV +I VG+I Q+KYGDLLPADG+
Sbjct: 54  TAFNDWSKEKQFRGLQSKIEHEHRFTVIRNGELHQIPVGEILVGEICQIKYGDLLPADGV 233

Query: 230 LIQGNDLKIDESSLTGESDHVXXXXXXXXXXXXGTHVMEGSGRMVVTAVGVNSQTGIIFT 289
           +IQ NDLK     +                         G  +MVVTAVGVNSQTGIIF 
Sbjct: 234 IIQSNDLKNRREFVNRRVGPCEKGRGQGPHAFVRHPCNGGQWKMVVTAVGVNSQTGIIFA 413

Query: 290 LLGA 293
           LLGA
Sbjct: 414 LLGA 425
>36566
          Length = 589

 Score =  127 bits (320), Expect = 2e-29,   Method: Compositional matrix adjust.
 Identities = 59/147 (40%), Positives = 98/147 (66%)
 Frame = +3

Query: 791 VVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYD 850
           VV +TGDG ND  ALK A++G +MG++GTDV+KEASD+IL DD+FT+I+ A+  G+ ++ 
Sbjct: 126 VVGMTGDGVNDAVALKSAEIGISMGVSGTDVSKEASDMILVDDDFTTILNAIEEGKGIFY 305

Query: 851 SISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTLASLALATEPPTES 910
           +I  F++FQL+ ++ A+ +      +   +PL A+Q+LW+N+IMD   + +L  EP    
Sbjct: 306 NIRNFVRFQLSTSIAALSLIAVSTLLRLPNPLNAMQILWINIIMDGPPAQSLGVEPVDHD 485

Query: 911 LLLRKPYGRNKPLISRTMMKNILGHAF 937
           ++ + P     P+I+R ++ N+L  A 
Sbjct: 486 VIKQPPRHVGDPIITRRLIINVLSSAL 566
>08160
          Length = 459

 Score = 65.5 bits (158), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 30/60 (50%), Positives = 42/60 (70%)
 Frame = +2

Query: 434 GLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTMNRMTVVQAYIN 493
           GL   VT+ L  + K+M + N LV++L+A ET+G+ + ICSDKTGTLT NRMTV   + +
Sbjct: 2   GLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFD 181
>14773
          Length = 794

 Score = 61.6 bits (148), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 38/134 (28%), Positives = 69/134 (51%), Gaps = 8/134 (5%)
 Frame = +2

Query: 819 TDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQ 878
           +DV+K+A+D+IL DDNF SIV  V  GR ++D++ K + + LT N+  +           
Sbjct: 2   SDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEISPFLVYILFGT 181

Query: 879 DSPLKAVQMLWVNLIMDTLASLALATEPPTESLLLRKPYGRNKPLISRTMMKNILGH--- 935
             PL  + +L+++L  D + +++LA E     ++ R P   +  L++  ++    G    
Sbjct: 182 PLPLGVITILFIDLGTDMVPAISLAYEMAESDIMKRPPRTISDRLVNERLIAMSYGQIGM 361

Query: 936 -----AFYQLVVVF 944
                 FY  ++VF
Sbjct: 362 MQALAGFYAWILVF 403
>28890
          Length = 552

 Score = 54.3 bits (129), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 25/57 (43%), Positives = 37/57 (64%)
 Frame = -3

Query: 192 QKFTVIRGGQVIQIPVADITVGDIAQVKYGDLLPADGILIQGNDLKIDESSLTGESD 248
           Q   V+RG Q + +   ++ VGDI + K+GD +PAD  +I  +  K+D SSLTGES+
Sbjct: 475 QFAVVVRGDQKLSVKAEELVVGDIVECKFGDRVPADLRVISAHGFKVDNSSLTGESE 305
>04985
          Length = 1671

 Score = 51.6 bits (122), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 56/210 (26%), Positives = 92/210 (43%), Gaps = 16/210 (7%)
 Frame = -1

Query: 753  ERIDKIWPKLRVLARSSPTDKHTLVKGIIDSTVSEQRQVVAVTGDGTNDGPALKKADVGF 812
            E + K+  +  V AR +P  K  L++ +          +V + GDG ND  ALK A  G 
Sbjct: 1641 ELLPKVCTQGTVFARMAPDQKCALIENL-----QSYDYIVGMCGDGANDCEALKAAHAGI 1477

Query: 813  AMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNV---------YDSISKFLQFQLTVN 863
            ++  A   VA   +  I   +N   +V A+  GR           Y ++  F+QF     
Sbjct: 1476 SLSEAEASVAAPFTSRI---NNIECVVTAMREGRAALVTSFGCFKYMALYSFIQF----- 1321

Query: 864  VVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTLASLALATEPPTESLLLRKPYGRNKPL 923
             ++V++ +T  C T  S L   + L+++LI+ T  ++ L      + L+      R+KP 
Sbjct: 1320 -ISVLILYT--CQTNLSDL---EFLYIDLIITTTIAVLLGYTGAYDKLV------RHKPP 1177

Query: 924  ISRTMMKNILG-------HAFYQLVVVFTL 946
             S   + NI+         A YQL  +F L
Sbjct: 1176 DSLMKLSNIISILMQVTLTAAYQLSTLFYL 1087
>13525
          Length = 645

 Score = 42.7 bits (99), Expect = 8e-04,   Method: Composition-based stats.
 Identities = 17/33 (51%), Positives = 26/33 (78%)
 Frame = +2

Query: 446 SVKKMMKDNNLVRHLDACETMGNATAICSDKTG 478
           + K+M + N LV++L+A ET+G+ + ICSDKTG
Sbjct: 5   TAKRMARKNCLVKNLEAVETLGSTSTICSDKTG 103
>33697
          Length = 310

 Score = 39.3 bits (90), Expect = 0.010,   Method: Composition-based stats.
 Identities = 18/34 (52%), Positives = 24/34 (70%)
 Frame = -2

Query: 684 DPVRPEVPEAIKKCQRAGITVRMVTGDNINTARA 717
           DP R  VP+A+ KC+ AGI V MVTGD+  T++ 
Sbjct: 195 DPPRAAVPDAVGKCRSAGIKVIMVTGDHPITSQG 94
>14321
          Length = 568

 Score = 38.5 bits (88), Expect = 0.016,   Method: Compositional matrix adjust.
 Identities = 23/57 (40%), Positives = 31/57 (54%)
 Frame = +2

Query: 758 IWPKLRVLARSSPTDKHTLVKGIIDSTVSEQRQVVAVTGDGTNDGPALKKADVGFAM 814
           + P  RV AR +P  K  ++     + +  Q  V  + GDGTND  ALK ADVG A+
Sbjct: 248 LLPNTRVFARVAPKQKELII-----TVLKAQGFVTLMCGDGTNDVGALKHADVGVAL 403
>07486
          Length = 763

 Score = 38.1 bits (87), Expect = 0.021,   Method: Composition-based stats.
 Identities = 20/43 (46%), Positives = 27/43 (62%)
 Frame = -1

Query: 804 ALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGR 846
           AL +ADVG A+G  GTDVA EA+DI+L   +   +  A+   R
Sbjct: 742 ALAQADVGIAIG-TGTDVAVEAADIVLMKSDLVDVYAAIKLSR 617
>21117
          Length = 462

 Score = 30.4 bits (67), Expect = 4.5,   Method: Composition-based stats.
 Identities = 26/81 (32%), Positives = 34/81 (41%)
 Frame = -3

Query: 170 TAFNDWSKEKQFRGLQSRIEQEQKFTVIRGGQVIQIPVADITVGDIAQVKYGDLLPADGI 229
           TA  + S       L+SR        + R G+       D  VGD   V  GDL    G+
Sbjct: 382 TASANCSTSTSILALRSRTRHSLSPVLKRDGET------DRLVGDRDLVGDGDLNGETGL 221

Query: 230 LIQGNDLKIDESSLTGESDHV 250
           L+  NDL  D   L G++D V
Sbjct: 220 LLGDNDLDGDAGLLVGDNDLV 158
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6754012|ref|NP_034438.1| guanine nucleotide binding
protein, alpha o isoform A [Mus musculus]
         (354 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

11965                                                                 404   e-113
13527                                                                 335   1e-92
29196                                                                 154   6e-38
20516                                                                 108   3e-24
34094                                                                  69   4e-12
08153                                                                  47   8e-06
09827                                                                  47   1e-05
10862                                                                  43   2e-04
18949                                                                  40   0.002
11378                                                                  36   0.021
18208                                                                  32   0.33 
>11965
          Length = 3256

 Score =  404 bits (1038), Expect = e-113,   Method: Compositional matrix adjust.
 Identities = 186/221 (84%), Positives = 201/221 (90%)
 Frame = +1

Query: 134 DSGIQECFNRSREYQLNDSAKYYLDSLDRIGAGDYQPTEQDILRTRVKTTGIVETHFTFK 193
           DSG+Q+CF+RS EYQLNDSAKY+LD LDR+G  DY PTEQDILRTRVKTTGIVE HF+FK
Sbjct: 1   DSGVQDCFSRSNEYQLNDSAKYFLDDLDRLGTKDYMPTEQDILRTRVKTTGIVEVHFSFK 180

Query: 194 NLHFRLFDVGGQRSERKKWIHCFEDVTAIIFCVALSGYDQVLHEDETTNRMHESLMLFDS 253
           NL+F+LFDVGGQRSERKKWIHCFEDVTAIIFCVA+S YDQVLHEDETTNRM ESL LFDS
Sbjct: 181 NLNFKLFDVGGQRSERKKWIHCFEDVTAIIFCVAMSEYDQVLHEDETTNRMQESLKLFDS 360

Query: 254 ICNNKFFIDTSIILFLNKKDLFGEKIKKSPLTICFPEYPGSNTYEDAAAYIQTQFESKNR 313
           ICNNK+F DTSIILFLNKKDLF EKIKKSPLT+CFPEY G  TYE+ AAYIQ QFE+KN+
Sbjct: 361 ICNNKWFTDTSIILFLNKKDLFEEKIKKSPLTVCFPEYTGKQTYEEVAAYIQAQFEAKNK 540

Query: 314 SPNKEIYCHMTCATDTNNIQVVFDAVTDIIIANNLRGCGLY 354
           S  KEIYCH TCATDTNNIQ VFDAVTD+IIANNLRGCGLY
Sbjct: 541 SSQKEIYCHQTCATDTNNIQFVFDAVTDVIIANNLRGCGLY 663
>13527
          Length = 1091

 Score =  335 bits (860), Expect = 1e-92,   Method: Compositional matrix adjust.
 Identities = 156/198 (78%), Positives = 179/198 (90%)
 Frame = -2

Query: 1    MGCTLSAEERAALERSKAIEKNLKEDGISAAKDVKLLLLGAGESGKSTIVKQMKIIHEDG 60
            MGCTLSAEERAA+ERSKAIEKNLKEDG+ AAKD+KLLLLGAGESGKSTIVKQMKIIHE G
Sbjct: 1042 MGCTLSAEERAAMERSKAIEKNLKEDGMQAAKDIKLLLLGAGESGKSTIVKQMKIIHEGG 863

Query: 61   FSGEDVKQYKPVVYSNTIQSLAAIVRAMDTLGVEYGDKERKTDSKMVCDVVSRMEDTEPF 120
            F+ ED KQY+PVV+SNTIQSL AI+RAM TL + +GD ER++D+KMV DV++RMEDTEPF
Sbjct: 862  FTSEDNKQYRPVVFSNTIQSLVAIIRAMGTLSIPFGDNERESDAKMVLDVIARMEDTEPF 683

Query: 121  SAELLSAMMRLWGDSGIQECFNRSREYQLNDSAKYYLDSLDRIGAGDYQPTEQDILRTRV 180
            S ELL+AM RLW DSG+Q+CF+RS EYQLNDSAKY+LD LDR+G  DY PTEQDILRTRV
Sbjct: 682  SEELLAAMERLWMDSGVQDCFSRSNEYQLNDSAKYFLDDLDRLGTKDYMPTEQDILRTRV 503

Query: 181  KTTGIVETHFTFKNLHFR 198
            KTTGIVE HF+FKNL+F+
Sbjct: 502  KTTGIVEVHFSFKNLNFK 449
>29196
          Length = 431

 Score =  154 bits (389), Expect = 6e-38,   Method: Compositional matrix adjust.
 Identities = 87/147 (59%), Positives = 99/147 (67%), Gaps = 4/147 (2%)
 Frame = -2

Query: 126 SAMMRLWGDSGIQEC----FNRSREYQLNDSAKYYLDSLDRIGAGDYQPTEQDILRTRVK 181
           +AM RLW DSG+QEC     N +    LN S    +    RI +   QP  +       +
Sbjct: 430 AAMKRLWLDSGVQECSRAATNTN*TIPLNISWMI*IG*ALRITS---QPN-RTFCAPESR 263

Query: 182 TTGIVETHFTFKNLHFRLFDVGGQRSERKKWIHCFEDVTAIIFCVALSGYDQVLHEDETT 241
              +       KNL+F+LFDVGGQRSERKKWIHCFEDVTAIIFCVA+S YDQVLHEDETT
Sbjct: 262 PPAL*RFISPLKNLNFKLFDVGGQRSERKKWIHCFEDVTAIIFCVAMSEYDQVLHEDETT 83

Query: 242 NRMHESLMLFDSICNNKFFIDTSIILF 268
           NRM ESL LFDSICNNK+F DTSIILF
Sbjct: 82  NRMQESLKLFDSICNNKWFTDTSIILF 2
>20516
          Length = 534

 Score =  108 bits (270), Expect = 3e-24,   Method: Compositional matrix adjust.
 Identities = 68/161 (42%), Positives = 93/161 (57%), Gaps = 2/161 (1%)
 Frame = +2

Query: 191 TFKNLHFRLFDV-GGQRSERKKWIHCFEDVTAIIFCVALSGYDQVLHEDETTNRMHESLM 249
           TF+N+ F + +V GGQRS+R+KW  CF  +T+I+F  A S +DQVL ED  TNR+ ES  
Sbjct: 41  TFRNIFFLVGEVTGGQRSQRQKWYQCFVGITSILFLAASSEFDQVLMEDRKTNRLQESCD 220

Query: 250 LFDSICNNKFFIDTSIILFLNKKDLFGEKIKKSPLTICFPEYPGSNTYEDAAAYIQTQFE 309
           +F++I NNK F   SIILFLNK DL  +K     L   F  + G +     +  I     
Sbjct: 221 IFETIINNKSFSGVSIILFLNKMDLLQDKN*ACQLRRLFSRFSG*SQGH*CSQSI*ASAV 400

Query: 310 SKNRSPNKEIYC-HMTCATDTNNIQVVFDAVTDIIIANNLR 349
               + +K+ +  H T A DT NI+ VF  V D I+ +NLR
Sbjct: 401 *FAPT*SKQTFVHHFTTAIDTENIKHVFQDVKDTILHDNLR 523
>34094
          Length = 452

 Score = 68.6 bits (166), Expect = 4e-12,   Method: Compositional matrix adjust.
 Identities = 31/57 (54%), Positives = 40/57 (70%)
 Frame = +1

Query: 54  KIIHEDGFSGEDVKQYKPVVYSNTIQSLAAIVRAMDTLGVEYGDKERKTDSKMVCDV 110
           +IIHE G+S E+  QYKPVVYSN IQS+ AIVRAM+ L VE+G  +R       C++
Sbjct: 103 RIIHEKGYSQEECLQYKPVVYSNAIQSMIAIVRAMNLLSVEFGHPDRAVSLFKSCNL 273
>08153
          Length = 1703

 Score = 47.4 bits (111), Expect = 8e-06,   Method: Compositional matrix adjust.
 Identities = 30/97 (30%), Positives = 46/97 (47%)
 Frame = +1

Query: 178 TRVKTTGIVETHFTFKNLHFRLFDVGGQRSERKKWIHCFEDVTAIIFCVALSGYDQVLHE 237
           T + T G       +KN+ F ++DVGGQ   R  W H F++   +IF V  +  +++   
Sbjct: 163 TTIPTIGFNVETVEYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERINEA 342

Query: 238 DETTNRMHESLMLFDSICNNKFFIDTSIILFLNKKDL 274
            E   RM     L D+I          I++F NK+DL
Sbjct: 343 KEELARMLNEDDLRDAI----------ILVFANKQDL 423
>09827
          Length = 1201

 Score = 47.0 bits (110), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 29/97 (29%), Positives = 44/97 (45%)
 Frame = -3

Query: 178  TRVKTTGIVETHFTFKNLHFRLFDVGGQRSERKKWIHCFEDVTAIIFCVALSGYDQVLHE 237
            T + T G       +KN+ F ++DVGGQ   R  W H F++   +IF V  +  ++V   
Sbjct: 1034 TTIPTIGFNVETVEYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDKERVQEA 855

Query: 238  DETTNRMHESLMLFDSICNNKFFIDTSIILFLNKKDL 274
             E   RM           N     D  +++F NK+DL
Sbjct: 854  REELTRM----------LNEDELRDAVLLVFANKQDL 774
>10862
          Length = 2896

 Score = 42.7 bits (99), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 25/83 (30%), Positives = 39/83 (46%)
 Frame = -3

Query: 192  FKNLHFRLFDVGGQRSERKKWIHCFEDVTAIIFCVALSGYDQVLHEDETTNRMHESLMLF 251
             +   F ++DVGGQ   R  W H +     +IF V  +  D++   DE    +H      
Sbjct: 2495 LQECQFNVWDVGGQDKIRPLWRHYYTGTQGLIFVVDCADRDRI---DEARQELHR----- 2340

Query: 252  DSICNNKFFIDTSIILFLNKKDL 274
              I N++   D  I++F NK+DL
Sbjct: 2339 --IINDREMRDAIILIFANKQDL 2277
>18949
          Length = 414

 Score = 40.0 bits (92), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 23/87 (26%), Positives = 36/87 (41%)
 Frame = +3

Query: 190 FTFKNLHFRLFDVGGQRSERKKWIHCFEDVTAIIFCVALSGYDQVLHEDETTNRMHESLM 249
            +   + F  FD+GG R  R+ W   F  V  I+F V +            T R+ E+  
Sbjct: 42  LSMGGMTFTTFDLGGHRQARRVWKDYFPAVDGIVFIVDV----------HDTERITEAKA 191

Query: 250 LFDSICNNKFFIDTSIILFLNKKDLFG 276
             DS+  +    D  +++  NK D  G
Sbjct: 192 ELDSLLRDDQIADIPVLVLGNKMDKHG 272
>11378
          Length = 1688

 Score = 36.2 bits (82), Expect = 0.021,   Method: Compositional matrix adjust.
 Identities = 26/100 (26%), Positives = 42/100 (42%)
 Frame = +3

Query: 174 DILRTRVKTTGIVETHFTFKNLHFRLFDVGGQRSERKKWIHCFEDVTAIIFCVALSGYDQ 233
           D +   V T        +   + F  FD+GG R  R+ W   F  V  I+F V       
Sbjct: 390 DKMAQHVPTLHPTSEELSMGGMRFTTFDLGGHRQARRVWKDYFPAVDGIVFLVD------ 551

Query: 234 VLHEDETTNRMHESLMLFDSICNNKFFIDTSIILFLNKKD 273
            +H+ E   R+ E+    DS+  ++   +  I++  NK D
Sbjct: 552 -VHDRE---RLVEAKAELDSLMTDEQVANAPILVLGNKID 659
>18208
          Length = 458

 Score = 32.3 bits (72), Expect = 0.33,   Method: Compositional matrix adjust.
 Identities = 11/34 (32%), Positives = 19/34 (55%)
 Frame = -1

Query: 193 KNLHFRLFDVGGQRSERKKWIHCFEDVTAIIFCV 226
           K     ++D+GGQR  R  W + FE+   +I+ +
Sbjct: 176 KGFKLNVWDIGGQRRIRPYWKNYFENTDLLIYVI 75
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|22122625|ref|NP_666220.1|
3-hydroxyisobutyryl-Coenzyme A hydrolase [Mus musculus]
         (385 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

36681                                                                 399   e-112
13881                                                                  69   3e-12
11398                                                                  38   0.006
04023                                                                  36   0.025
26426                                                                  34   0.085
04595                                                                  31   0.75 
>36681
          Length = 1210

 Score =  399 bits (1026), Expect = e-112,   Method: Compositional matrix adjust.
 Identities = 195/360 (54%), Positives = 260/360 (72%), Gaps = 2/360 (0%)
 Frame = +3

Query: 21  VILQHLRMSMHTEAA--EVLLERRGCGGVITLNRPKFLNALSLNMIRQIYPQLKTWEQDP 78
           VIL+H+RM+  +  A  EVL    G   VI LNRPK LNAL+LNMIR IYP++  WE DP
Sbjct: 6   VILKHVRMAQLSSQATDEVLFNAVGDKRVIVLNRPKALNALNLNMIRHIYPKMLEWETDP 185

Query: 79  DTFLXXXXXXXXXXXXXXXDIKALSEAKKARQNLTQDLFREEYILNNAIASCQKPYVALI 138
           +                  DI+A++E+ K   +L +D F+EEY+LN  I S +KPY+A+I
Sbjct: 186 NISCVVIKGAGDKAFCAGGDIRAVTESGKVGGDLGKDFFKEEYMLNYKIGSYRKPYIAVI 365

Query: 139 DGITMGGGVGLSVHGQFRVATERSLFAMPETGIGLFPDVGGGYFLPRLQGKLGYFLALTG 198
           DGITMGGGVGLSVHG++RVATE+++FAMPET IGLFPDVGGG+FLP LQG+LG +LALTG
Sbjct: 366 DGITMGGGVGLSVHGKYRVATEKTVFAMPETAIGLFPDVGGGHFLPWLQGRLGTYLALTG 545

Query: 199 YRLKGRDVHRAGIATHFVDSEKLRVLEEELLALKSPSAEDVAGVLESYHAKSKMDQDKSI 258
           +RLKGRDV  AG+ATHFV +EKL  LE+ L+ L   S   V  VL+SYH+++ +D+DK  
Sbjct: 546 FRLKGRDVFHAGVATHFVQAEKLAELEQSLMQLPEASHLQVEKVLDSYHSQNPVDKDKPF 725

Query: 259 IFEEHMDKINSCFSANTVEQIIENLRQDGSPFAIEQMKVINKMSPTSLKITLRQLMEGSS 318
           +   H+D INS F  ++VE I+++L+   S +A  Q+  INKMSPTSLK+TLRQL  G +
Sbjct: 726 VLAPHLDTINSVFDKDSVEDIVQHLQSLPSEWAQLQLNTINKMSPTSLKVTLRQLRMGET 905

Query: 319 KTLQEVLIMEYRITQACMEGHDFHEGVRAVLIDKDQTPKWKPANLKDVTDEDLNSYFKSL 378
            +L ++L +EYR++Q C++ HDF+EGVRAVL+DKDQ+P+W P +L+ VT E L+ YF  L
Sbjct: 906 LSLADILQVEYRLSQRCLKDHDFYEGVRAVLVDKDQSPRWNPDSLEGVTTEKLDWYFSPL 1085
>13881
          Length = 1594

 Score = 68.9 bits (167), Expect = 3e-12,   Method: Compositional matrix adjust.
 Identities = 55/223 (24%), Positives = 101/223 (45%), Gaps = 6/223 (2%)
 Frame = +3

Query: 25  HLRMSMHTEAAEVLLERRGCG-----GVITLNRPKFLNALSLNMIRQIYPQLKTWEQDPD 79
           H R+    +   VL+ER  CG      V+ +NRP+  NALS  ++  +   L+  +QD +
Sbjct: 72  HARLLSTGKFQNVLVER--CGDKHNVAVVRMNRPRTFNALSDALMADVTAALQQLDQD-N 242

Query: 80  TFLXXXXXXXXXXXXXXXDIKALSEAKKARQNLTQDLFREEYILNNAIASCQKPYVALID 139
           +                 D+  L   KK  +++ +  F  ++    +I+ C+KP +A ++
Sbjct: 243 SVGCIVLTGSDRAFAAGADVPDLH--KKTFEDVIEQDFPAQFY---SISKCRKPIIAAVN 407

Query: 140 GITMGGGVGLSVHGQFRVATERSLFAMPETGIGLFPDVGGGYFLPRLQGKLGYF-LALTG 198
           G  +GGG  +++      A +++LFA PE  +G  P  GG   L R  GK     + ++ 
Sbjct: 408 GYALGGGXEIAMMCDIVYAGDKALFAQPEVTLGTLPGAGGTQRLIRAVGKSKAMEMVISA 587

Query: 199 YRLKGRDVHRAGIATHFVDSEKLRVLEEELLALKSPSAEDVAG 241
            ++   +  R G+ +    +        E+L     +AE +AG
Sbjct: 588 NKITAHEAERMGLVSKVFPA-------SEVLDAAVQTAEKIAG 695
>11398
          Length = 3234

 Score = 38.1 bits (87), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 24/77 (31%), Positives = 39/77 (50%), Gaps = 3/77 (3%)
 Frame = -3

Query: 143  MGGGVGLSVHGQFRVAT--ERSLFAMPETGIGLFPDVGGGYFLPRLQG-KLGYFLALTGY 199
            +GGG  +++  Q+RVA   +++  A+PE  +GL P  GG   LP+L        + LTG 
Sbjct: 3226 LGGGFEVALACQYRVAVADKKTTVALPEVMLGLLPGAGGTQRLPKLVPIPTALDMMLTGK 3047

Query: 200  RLKGRDVHRAGIATHFV 216
             +K     + G+    V
Sbjct: 3046 TIKADRAKKMGLVDQLV 2996
>04023
          Length = 997

 Score = 36.2 bits (82), Expect = 0.025,   Method: Compositional matrix adjust.
 Identities = 23/69 (33%), Positives = 35/69 (50%), Gaps = 3/69 (4%)
 Frame = +2

Query: 157 VATERSLFAMPETGIGLF---PDVGGGYFLPRLQGKLGYFLALTGYRLKGRDVHRAGIAT 213
           VATE+S FA P   +GLF   P V  G  +PR   K+   +  TG  +  +D    G+ +
Sbjct: 32  VATEQSRFATPGVHVGLFCTTPGVAVGRAVPR---KVALEMMFTGQPISAQDALLHGLVS 202

Query: 214 HFVDSEKLR 222
             V  ++L+
Sbjct: 203 KVVPEDRLQ 229
>26426
          Length = 413

 Score = 34.3 bits (77), Expect = 0.085,   Method: Compositional matrix adjust.
 Identities = 28/113 (24%), Positives = 44/113 (38%)
 Frame = +2

Query: 50  LNRPKFLNALSLNMIRQIYPQLKTWEQDPDTFLXXXXXXXXXXXXXXXDIKALSEAKKAR 109
           LNRP   NA S  M+      L+  + D D+ +               D+K   E K   
Sbjct: 2   LNRPAAKNAFSRGMVTTFRDILE*IKSDNDSRVVVLRSLTPGIFCAGADLK---ERKGMT 172

Query: 110 QNLTQDLFREEYILNNAIASCQKPYVALIDGITMGGGVGLSVHGQFRVATERS 162
              T+    E   L  +I     P +A +DG  +GGG+ +++    R A   +
Sbjct: 173 TEETKQFVTELRALLVSIEQLPMPVIAALDGAALGGGLEMALACDIRTAASNA 331
>04595
          Length = 1947

 Score = 31.2 bits (69), Expect = 0.75,   Method: Compositional matrix adjust.
 Identities = 26/81 (32%), Positives = 41/81 (50%), Gaps = 12/81 (14%)
 Frame = +2

Query: 117 FREEYILN-----NAIASCQKPYVALIDGITMGG------GVGLSVHG-QFRVATERSLF 164
           F E Y  N     +A+A C+KP +A ++G  +GG       V LS+ G +  + ++RS +
Sbjct: 26  FAETYNSNFLMDWDAVAKCRKPIIAAVNGYALGGVVSWP*CVTLSMLGTRHSLDSQRSPW 205

Query: 165 AMPETGIGLFPDVGGGYFLPR 185
           A P    G+  D  G +  PR
Sbjct: 206 A-PFQVRGVHSDXCGRWESPR 265
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|27370360|ref|NP_766478.1| gamma-aminobutyric acid
(GABA-A) transporter 4 [Mus musculus]
         (627 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

08387                                                                 400   e-112
15924                                                                 293   2e-79
08953                                                                 282   2e-76
32211                                                                 217   1e-56
21405                                                                 140   2e-46
18526                                                                 169   3e-42
14556                                                                 150   1e-36
19604                                                                 135   4e-32
02570                                                                 121   1e-27
26872                                                                 119   4e-27
33291                                                                  72   2e-21
26038                                                                  96   3e-20
25926                                                                  84   2e-16
14638                                                                  81   1e-15
21870                                                                  69   9e-13
31151                                                                  52   6e-07
05476                                                                  29   5.4  
37391                                                                  28   8.1  
04357                                                                  28   8.1  
>08387
          Length = 4991

 Score =  400 bits (1029), Expect = e-112,   Method: Compositional matrix adjust.
 Identities = 211/422 (50%), Positives = 276/422 (65%), Gaps = 9/422 (2%)
 Frame = -2

Query: 204  RRVLAISDGIEHIGNLRWELALCLLAAWTICYFCIWKGTKSTGKVVYVTATFPYIMLLIL 263
             +VL ISDGI+ +G ++W+LALCLL AW + Y CI KG +S+GKV+YVTAT PYI +LIL
Sbjct: 4423 EQVLKISDGIDDMGTVKWDLALCLLLAWVVVYACICKGIRSSGKVMYVTATSPYIFMLIL 4244

Query: 264  LIRGVTLPGASEGIKFYLYPDLSRLSDPQVWVDAGTQIFFSYAICLGCLTALGSXXXXXX 323
            LIR   L GA EG+ FYL P++++L + +VWVDAGTQIFFS +I LG LTALGS      
Sbjct: 4243 LIRNSLLDGAKEGVDFYLTPNMTKLGEMEVWVDAGTQIFFSSSIALGTLTALGSYNKFKH 4064

Query: 324  XCYRDCIMLCCLNSGTSFVAGFAIFSVLGFMAYEQGVPIAEVAESGPGLAFIAYPKAVTM 383
              YRD ++   +NS TSF AGF +F++LG+MA  Q  PI +VAESGPGLAFIAYPKAV  
Sbjct: 4063 NSYRDSVIFALVNSVTSFFAGFIVFTILGYMAKLQNRPIKDVAESGPGLAFIAYPKAVAQ 3884

Query: 384  MPLSPLWATLFFMMLIFLGLDSQFVCVESLVTAVVDMYPKVFRRGYRRELLILALSIISY 443
            MPLSPLW+ LFF+M+I LGLDSQFV VE +VT +VD YP++ R+GYR+E+ I  + II +
Sbjct: 3883 MPLSPLWSILFFLMVILLGLDSQFVGVEGVVTTIVDQYPRLLRKGYRKEIFIGFICIIMF 3704

Query: 444  FLGLVMLTEGGMYIFQLFDSYAASGMCLLFVAIFECVCIGWVYGSNRFYDNIEDMIG--- 500
            F+GL M++ GGMY+FQLFD Y+ S + LL VA FE + I ++YG  RF DNI+ M+G   
Sbjct: 3703 FVGLAMVSNGGMYVFQLFDYYSGSRIILL-VAFFELIGISYIYGVFRFLDNIKMMLGDHW 3527

Query: 501  -YRPLSLIKWCWKVVTPGICAGIFIFFLVKYKPLKY-----NNVYTYPAWGYGIGWLMAL 554
              + L  +  CW V++P  C  IF+   + Y  L Y        Y YP W  GIGW +A 
Sbjct: 3526 MVKTLPFMVVCWTVLSPAFCIAIFVMSAINYSELDYARPGSKGTYVYPDWAVGIGWALAA 3347

Query: 555  SSMLCIPLWIFIKLWKTEGTLPEKLQKLTVPSADLKMRGKLGASPRTVTVNDCEAKVKGD 614
            SS + IP+ + I  W   G   E L+ L  P   LK            T+ D E +  G+
Sbjct: 3346 SSAVWIPI-VAIYKWVKNGATLEALKLLCKPYG-LKEHQLREQDKGERTLADLERERAGE 3173

Query: 615  GT 616
             +
Sbjct: 3172 QS 3167

 Score =  103 bits (256), Expect = 3e-22,   Method: Compositional matrix adjust.
 Identities = 60/142 (42%), Positives = 84/142 (59%), Gaps = 3/142 (2%)
 Frame = -1

Query: 82   AFLIPYVVFFICCGIPVFFLETALGQFTSEGGITCWRRVCPLFEGIGYATQVIEAHLNVY 141
            AFLIPY +  I  GIP+F+LE A+GQF + GG+  W  V P+ +GIG A+ +I   LN Y
Sbjct: 4790 AFLIPYFICVIFGGIPLFYLEVAVGQFMNRGGLQAWNLV-PILQGIGLASCIIVFFLNCY 4614

Query: 142  YIIILAWAIFYLSNCFTTELPWATCGHEWNTEK--CVEFQ-KLNFSNYSHVSLQNATSPV 198
            Y +IL WA +Y  + FT+ELPW TC H+WN +    V+FQ K+N +   +++ +    PV
Sbjct: 4613 YNVILTWAFYYFFSSFTSELPWETCDHDWNNKTVCAVDFQAKVNETGDPNIT-KILVDPV 4437

Query: 199  MEFWERRVLAISDGIEHIGNLR 220
             E       +    IE IG  R
Sbjct: 4436 TE-------SGRTSIEDIGRYR 4392

 Score = 54.7 bits (130), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 25/54 (46%), Positives = 35/54 (64%)
 Frame = -3

Query: 40   KAVHERGHWNNKVEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFLIPYVVFFIC 93
            K +++R  W    +F+L+  G  +GLGNVWRFPYLCYKNG G   +P  +  +C
Sbjct: 4914 KDLNKREQWGRAFDFLLACIGFSVGLGNVWRFPYLCYKNGEG---LPDPLLHLC 4762
>15924
          Length = 2588

 Score =  293 bits (749), Expect = 2e-79,   Method: Compositional matrix adjust.
 Identities = 150/375 (40%), Positives = 234/375 (62%), Gaps = 2/375 (0%)
 Frame = +3

Query: 196 SPVMEFWERRVLAISDGIE--HIGNLRWELALCLLAAWTICYFCIWKGTKSTGKVVYVTA 253
           SP  ++  + VL +++  +  ++G +  ++ L L  AW + +FC+ KG KS+GKVVY TA
Sbjct: 69  SPAADYLSQYVLRLNEATDMANLGGISLKMILTLALAWLLIFFCLMKGVKSSGKVVYFTA 248

Query: 254 TFPYIMLLILLIRGVTLPGASEGIKFYLYPDLSRLSDPQVWVDAGTQIFFSYAICLGCLT 313
           TFPY++L++LL+RGVTL G  +G+KFY+ P+  +L+D +VW DA TQIF+S  +  G L 
Sbjct: 249 TFPYVILVVLLVRGVTLEGHLDGVKFYVIPEWDKLADAKVWGDAATQIFYSLGVGFGGLL 428

Query: 314 ALGSXXXXXXXCYRDCIMLCCLNSGTSFVAGFAIFSVLGFMAYEQGVPIAEVAESGPGLA 373
            + S       CYRD IM+  +N  TS  AGFAIFS+LG MA+     + +VA SGPGLA
Sbjct: 429 TMASYNKFKNNCYRDAIMVAVINCSTSIFAGFAIFSLLGHMAHVNNQAVEDVASSGPGLA 608

Query: 374 FIAYPKAVTMMPLSPLWATLFFMMLIFLGLDSQFVCVESLVTAVVDMYPKVFRRGYRREL 433
           F+AYP+ +T +P   LW+ LFF M++ LGLDSQF  +E++++ + DM+P+  R+  R+ L
Sbjct: 609 FVAYPEGITKLPAQSLWSFLFFFMILTLGLDSQFAMMETVISGISDMFPRTLRK--RKVL 782

Query: 434 LILALSIISYFLGLVMLTEGGMYIFQLFDSYAASGMCLLFVAIFECVCIGWVYGSNRFYD 493
                 ++ + LG+   T+GGM++  L D Y+ S   L+FVA+ E +CI +VYG   F +
Sbjct: 783 FTFCACLVGFLLGIPQATKGGMWVLTLMDWYSGS-YNLMFVALAELICIMYVYGWRNFSN 959

Query: 494 NIEDMIGYRPLSLIKWCWKVVTPGICAGIFIFFLVKYKPLKYNNVYTYPAWGYGIGWLMA 553
           ++E M+G++P       W V+TP     I I   ++Y P  Y+  Y +  W  G+GW+M 
Sbjct: 960 DVEMMVGFKPNIYWLANWLVITPIAIGFIIIIGAIQYTPASYDG-YEFEDWVQGLGWVMV 1136

Query: 554 LSSMLCIPLWIFIKL 568
              +  I +  F+++
Sbjct: 1137TVPIASIFVVGFVQM 1181
>08953
          Length = 2245

 Score =  282 bits (722), Expect = 2e-76,   Method: Compositional matrix adjust.
 Identities = 149/349 (42%), Positives = 223/349 (63%)
 Frame = +1

Query: 222 ELALCLLAAWTICYFCIWKGTKSTGKVVYVTATFPYIMLLILLIRGVTLPGASEGIKFYL 281
           ++ L L  AW + +FC+ KG KS+GKVVY TATFPY++LL+LL+RGVTL G  EGIKFY 
Sbjct: 1   KIILTLALAWILIFFCLMKGVKSSGKVVYFTATFPYVILLVLLVRGVTLSGHLEGIKFYT 180

Query: 282 YPDLSRLSDPQVWVDAGTQIFFSYAICLGCLTALGSXXXXXXXCYRDCIMLCCLNSGTSF 341
            P   +L+D +VW DA TQIF+S  +  G L  + S       C+RD IM+  +N GTS 
Sbjct: 181 IPKWDKLADAKVWGDAATQIFYSLGVGFGGLLTMSSYSKFKNNCHRDAIMVALINCGTSI 360

Query: 342 VAGFAIFSVLGFMAYEQGVPIAEVAESGPGLAFIAYPKAVTMMPLSPLWATLFFMMLIFL 401
            AGFAIF++LG MAY     + +VA+SGPGLAF+AYP+ +T +P   LWA LFF M++ L
Sbjct: 361 FAGFAIFALLGHMAYVTNQDVDKVADSGPGLAFVAYPEGITKLPAMSLWAFLFFFMILTL 540

Query: 402 GLDSQFVCVESLVTAVVDMYPKVFRRGYRRELLILALSIISYFLGLVMLTEGGMYIFQLF 461
           GLDSQF  +E++++ + DM+P++ R+   +        ++ + LG+   T+GGM++  L 
Sbjct: 541 GLDSQFAMMETVISGISDMFPRLLRK--HKTFFTFICCLVGFLLGIPQATKGGMWVLTLM 714

Query: 462 DSYAASGMCLLFVAIFECVCIGWVYGSNRFYDNIEDMIGYRPLSLIKWCWKVVTPGICAG 521
           D Y+ S   L+FVA+ E +C+ +VYG N+FY++IE MIG++P    +  W  +TP     
Sbjct: 715 DWYSGS-YNLMFVALAEIICLMYVYGFNKFYEDIEMMIGHKPNYYWRIHWLAITPIAIIF 891

Query: 522 IFIFFLVKYKPLKYNNVYTYPAWGYGIGWLMALSSMLCIPLWIFIKLWK 570
           I +   V+Y P  Y+  Y +  W  G+GW+M    +  I +  F+++++
Sbjct: 892 IIVIGAVQYTPASYSG-YEFEBWVQGLGWVMVSVPIALIFIVGFVQMFR 1035
>32211
          Length = 836

 Score =  217 bits (553), Expect = 1e-56,   Method: Compositional matrix adjust.
 Identities = 103/185 (55%), Positives = 138/185 (74%)
 Frame = -1

Query: 331 MLCCLNSGTSFVAGFAIFSVLGFMAYEQGVPIAEVAESGPGLAFIAYPKAVTMMPLSPLW 390
           + CC      F       S+LGFMA  QG+ +A+VAESGPGLAFIAYP+AV  +P++PLW
Sbjct: 554 VFCCDQHVHQFPGRLCHLSILGFMAVRQGLDVADVAESGPGLAFIAYPEAVAQLPIAPLW 375

Query: 391 ATLFFMMLIFLGLDSQFVCVESLVTAVVDMYPKVFRRGYRRELLILALSIISYFLGLVML 450
           + +FF+M+I LGLDSQFV VE  +TAVVD+YP+V RRG+RRE+ I  + +I+YF+GL M+
Sbjct: 374 SVMFFVMVILLGLDSQFVGVEGFITAVVDLYPRVLRRGHRREVFIAIICVIAYFIGLSMV 195

Query: 451 TEGGMYIFQLFDSYAASGMCLLFVAIFECVCIGWVYGSNRFYDNIEDMIGYRPLSLIKWC 510
           TEGGMY+FQLFD Y+AS + L+ VA FEC+ + +VYG +RFYDN+E M G+R   L+K  
Sbjct: 194 TEGGMYVFQLFDYYSASRIVLV-VAFFECITVAYVYGVDRFYDNLEMMFGFRMGPLMKVS 18

Query: 511 WKVVT 515
           W  +T
Sbjct: 17  WMALT 3

 Score =  148 bits (374), Expect = 6e-36,   Method: Compositional matrix adjust.
 Identities = 71/112 (63%), Positives = 86/112 (76%)
 Frame = -2

Query: 237 CIWKGTKSTGKVVYVTATFPYIMLLILLIRGVTLPGASEGIKFYLYPDLSRLSDPQVWVD 296
           CIWKG KS+GKV+Y TAT PY+++ +LLIRGVTL GAS G+K+YL P+ SRL DPQVWVD
Sbjct: 835 CIWKGIKSSGKVMYFTATTPYVLMFVLLIRGVTLEGASTGLKYYLLPEWSRLKDPQVWVD 656

Query: 297 AGTQIFFSYAICLGCLTALGSXXXXXXXCYRDCIMLCCLNSGTSFVAGFAIF 348
           AGTQIFFSY+I LG LTALGS        +RD +    +N+ TSF+AGF IF
Sbjct: 655 AGTQIFFSYSISLGTLTALGSYNRFTHNVFRDSVCFAVINTFTSFLAGFVIF 500
>21405
          Length = 542

 Score =  140 bits (352), Expect(2) = 2e-46,   Method: Compositional matrix adjust.
 Identities = 65/125 (52%), Positives = 87/125 (69%)
 Frame = +2

Query: 430 RRELLILALSIISYFLGLVMLTEGGMYIFQLFDSYAASGMCLLFVAIFECVCIGWVYGSN 489
           R+E+ I  + ++SY +GL  +T+GGMYIFQ+ DSYA SG CLL++  FECV I W YG +
Sbjct: 170 RKEIFIAIVCMLSYLVGLTCITQGGMYIFQILDSYAVSGFCLLWLIFFECVSISWCYGVD 349

Query: 490 RFYDNIEDMIGYRPLSLIKWCWKVVTPGICAGIFIFFLVKYKPLKYNNVYTYPAWGYGIG 549
           RFYD I+DMIGY P    K+CW   TP IC G+F F +V++K +KY + Y+YP W +  G
Sbjct: 350 RFYDGIKDMIGYYPTVWWKFCWCFTTPAICLGVFFFNIVQWKSIKYLD-YSYPWWAHAFG 526

Query: 550 WLMAL 554
           W  AL
Sbjct: 527 WFTAL 541

 Score = 65.1 bits (157), Expect(2) = 2e-46,   Method: Compositional matrix adjust.
 Identities = 27/56 (48%), Positives = 40/56 (71%)
 Frame = +1

Query: 375 IAYPKAVTMMPLSPLWATLFFMMLIFLGLDSQFVCVESLVTAVVDMYPKVFRRGYR 430
           + YP AV  +P SP+W+ LFF ML+ +GLDSQF  +E  +TAV+D +P++ R+  R
Sbjct: 10  LVYPSAVLQLPGSPMWSCLFFFMLLLIGLDSQFCTMEGFITAVIDEWPQLLRKTQR 177
>18526
          Length = 537

 Score =  169 bits (429), Expect = 3e-42,   Method: Compositional matrix adjust.
 Identities = 80/173 (46%), Positives = 115/173 (66%)
 Frame = -2

Query: 216 IGNLRWELALCLLAAWTICYFCIWKGTKSTGKVVYVTATFPYIMLLILLIRGVTLPGASE 275
           +G +RW+L + L  +W   + C++KG K  GKV++  A FPY++LL+LLIRGVTLPGA +
Sbjct: 533 LGTVRWQLLITLAVSWLCVFLCLFKGVKVLGKVMHFAAPFPYMVLLVLLIRGVTLPGAID 354

Query: 276 GIKFYLYPDLSRLSDPQVWVDAGTQIFFSYAICLGCLTALGSXXXXXXXCYRDCIMLCCL 335
           GI FY+ P   +L + QVW DA  QIF+S  +  G +  + S        YRD +++  +
Sbjct: 353 GISFYIIPRWEKLLEFQVWGDAALQIFYSVGMAWGGIITMASYNKFNNNVYRDAMIVPLI 174

Query: 336 NSGTSFVAGFAIFSVLGFMAYEQGVPIAEVAESGPGLAFIAYPKAVTMMPLSP 388
           N GTS  AGF IFS+LGFMA+E G  + ++   GPGL F+AYP+AV+ +P+SP
Sbjct: 173 NCGTSIFAGFVIFSILGFMAHEAGKNVEDIVTQGPGLTFVAYPEAVSKLPISP 15
>14556
          Length = 552

 Score =  150 bits (380), Expect = 1e-36,   Method: Compositional matrix adjust.
 Identities = 68/137 (49%), Positives = 95/137 (69%), Gaps = 3/137 (2%)
 Frame = -2

Query: 44  ERGHWNNKVEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFLIPYVVFFICCGIPVFFLET 103
           ERG+W ++++F+LS  G  +GLGNVWRFPYL Y+NGG  FL PY++  I  G+P+FFLE 
Sbjct: 422 ERGNWGSQLDFLLSCVGYAVGLGNVWRFPYLAYRNGGATFLFPYIIMLIIAGLPLFFLEL 243

Query: 104 ALGQFTSEGGITCWRRVCPLFEGIGYATQVIEAHLNVYYIIILAWAIFYLSNCFT---TE 160
           ALGQF SEG IT W ++ P F GIG+A  +I   +++YY +I+ +AI+Y+   F     +
Sbjct: 242 ALGQFASEGPITVW-KMSPFFSGIGFAMCIISGVVSIYYNVIITYAIYYMFVSFVNLDND 66

Query: 161 LPWATCGHEWNTEKCVE 177
           LPWA+C H W T  C +
Sbjct: 65  LPWASCNHTWATPSCRD 15
>19604
          Length = 419

 Score =  135 bits (341), Expect = 4e-32,   Method: Compositional matrix adjust.
 Identities = 63/136 (46%), Positives = 90/136 (66%)
 Frame = -3

Query: 214 EHIGNLRWELALCLLAAWTICYFCIWKGTKSTGKVVYVTATFPYIMLLILLIRGVTLPGA 273
           E IG  RW LALCLL +W +   C+ KG KS+GKVVY TATFPY++L+ILLIRG  L GA
Sbjct: 408 ELIGTPRWRLALCLLLSWVVVILCLIKGIKSSGKVVYFTATFPYVILIILLIRGALLEGA 229

Query: 274 SEGIKFYLYPDLSRLSDPQVWVDAGTQIFFSYAICLGCLTALGSXXXXXXXCYRDCIMLC 333
            EG++F++ P+  +L+D +VWV A  Q+FFS ++  G +   GS        Y D +++ 
Sbjct: 228 KEGVEFFIIPEWDKLTDVKVWVAAAGQMFFSLSVSFGGIIMFGSYNKFTNNVYGDALLIS 49

Query: 334 CLNSGTSFVAGFAIFS 349
            ++  TS +AGF +F+
Sbjct: 48  VMDLVTSVIAGFVVFT 1
>02570
          Length = 1067

 Score =  121 bits (303), Expect = 1e-27,   Method: Compositional matrix adjust.
 Identities = 69/194 (35%), Positives = 112/194 (57%), Gaps = 4/194 (2%)
 Frame = -3

Query: 374  FIAYPKAVTMMPLSPLWATLFFMMLIFLGLDSQFVCVESLVTAVVDMYPKVFRRGYRREL 433
            F+AYP+A++ +P   LW+ LFF ML  LGLDS+F  +E+++T + D  P+   R Y + +
Sbjct: 1065 FVAYPEALSNLPPPQLWSVLFFFMLFTLGLDSEFGLMETILTCIQDEMPRX--RKY-KSV 895

Query: 434  LILALSIISYFLGLVMLTEGGMYIFQLFDSYAASGMCLLFVAIFECVCIGWVYGSNRFYD 493
            + +   I  YFL L  +  GG Y+  L D Y A    +L ++ FE + + W YG  RF  
Sbjct: 894  MCIGFGIGCYFLALPCVCNGGDYVVTLMDHYGAD-FSVLILSCFEVMSVMWXYGVMRFQK 718

Query: 494  NIEDMIGYRPLSLIKW--CWKVVTPGICAGIFIFFLVKYKPLKYNN--VYTYPAWGYGIG 549
            ++E M+G RP+    W  CW  + P + A +F++ +V+Y P  Y++  ++ YP +   IG
Sbjct: 717  DLEYMLGRRPMGWPYWVFCWS-IAPILIAALFLYRMVEYVPPHYDSEKLHPYPQFAQNIG 541

Query: 550  WLMALSSMLCIPLW 563
            W + +  +  IPLW
Sbjct: 540  WFLLVVVLCPIPLW 499
>26872
          Length = 406

 Score =  119 bits (298), Expect = 4e-27,   Method: Compositional matrix adjust.
 Identities = 58/132 (43%), Positives = 89/132 (67%)
 Frame = +2

Query: 372 LAFIAYPKAVTMMPLSPLWATLFFMMLIFLGLDSQFVCVESLVTAVVDMYPKVFRRGYRR 431
           L F+AYP+A++ +P +  WA +FF+ML+ LGLDS F   E+++TA+ D +P V RR   R
Sbjct: 2   LVFVAYPEAISTLPGASFWAVIFFLMLLTLGLDSSFGGSEAIITALSDEFP-VLRR--HR 172

Query: 432 ELLILALSIISYFLGLVMLTEGGMYIFQLFDSYAASGMCLLFVAIFECVCIGWVYGSNRF 491
           EL +LAL ++ + +GL    EGG+Y+  L D +AA G  +LF   FE + + W YG +RF
Sbjct: 173 ELFVLALFVLYFIVGLASCAEGGLYVVNLLDQFAA-GYSILFAVFFETLAVSWAYGLDRF 349

Query: 492 YDNIEDMIGYRP 503
            +++E M+G+RP
Sbjct: 350 SEDLEAMLGHRP 385
>33291
          Length = 467

 Score = 71.6 bits (174), Expect(2) = 2e-21,   Method: Composition-based stats.
 Identities = 32/59 (54%), Positives = 42/59 (71%)
 Frame = -1

Query: 327 RDCIMLCCLNSGTSFVAGFAIFSVLGFMAYEQGVPIAEVAESGPGLAFIAYPKAVTMMP 385
           RD I++  +N  TSF AGFAIFS+LGFMA  +GV + +V   G GL F+AYP+A+  MP
Sbjct: 317 RDSIIVPIINCLTSFYAGFAIFSILGFMAASKGVEVEDVTTDGTGLVFVAYPEALARMP 141

 Score = 49.3 bits (116), Expect(2) = 2e-21,   Method: Composition-based stats.
 Identities = 23/41 (56%), Positives = 28/41 (68%)
 Frame = -2

Query: 277 IKFYLYPDLSRLSDPQVWVDAGTQIFFSYAICLGCLTALGS 317
           IKFYL PD S+LS+  VW+ A  QIFFS +   G LTA+ S
Sbjct: 466 IKFYLQPDASKLSESSVWLAAAAQIFFSLSTSTGSLTAMSS 344

 Score = 38.9 bits (89), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 23/70 (32%), Positives = 31/70 (44%)
 Frame = -3

Query: 352 GFMAYEQGVPIAEVAESGPGLAFIAYPKAVTMMPLSPLWATLFFMMLIFLGLDSQFVCVE 411
           GF   +QG           G      P       L  LW+ LFF M+I LG+ +Q    E
Sbjct: 243 GFHGRQQGC*SRRRHHRRHGPGVCGLP*GAGQDALPQLWSVLFFFMMICLGMGTQIPSAE 64

Query: 412 SLVTAVVDMY 421
           +L+TA+ D Y
Sbjct: 63  TLLTALQDEY 34
>26038
          Length = 426

 Score = 96.3 bits (238), Expect = 3e-20,   Method: Compositional matrix adjust.
 Identities = 51/127 (40%), Positives = 76/127 (59%)
 Frame = -2

Query: 390 WATLFFMMLIFLGLDSQFVCVESLVTAVVDMYPKVFRRGYRRELLILALSIISYFLGLVM 449
           WA +FF ML+ LG+DS F  +ES +T + D    V R  Y RE+L L +   ++F  L  
Sbjct: 416 WAIIFFFMLLTLGIDSAFGGLESPLTGLHDELKTVMRMRYSREVLTLVVVGSAFFCSLPC 237

Query: 450 LTEGGMYIFQLFDSYAASGMCLLFVAIFECVCIGWVYGSNRFYDNIEDMIGYRPLSLIKW 509
           LTEGG+Y+F + D++AA G  +LF  + + + + W YG N+F  ++E M G +P    + 
Sbjct: 236 LTEGGIYVFTILDTFAA-GTSILFTVLCQVIAVSWFYGINQFCRDVEKMTGSQPSMYWRV 60

Query: 510 CWKVVTP 516
           CWK V P
Sbjct: 59  CWKFVCP 39
>25926
          Length = 675

 Score = 84.0 bits (206), Expect = 2e-16,   Method: Compositional matrix adjust.
 Identities = 42/105 (40%), Positives = 60/105 (57%), Gaps = 3/105 (2%)
 Frame = +1

Query: 484 WVYGSNRFYDNIEDMIGYRPLSLIKWCWKVVTPGICAGIFIFFLVKYKPLKYNN---VYT 540
           +VYG NRFYDN+E M G+R    +K CW V+TP     IFI   + Y  L Y      Y 
Sbjct: 1   FVYGVNRFYDNLEMMFGFRVGPWMKICWTVLTPLYTMVIFIMGCISYSDLTYKRKTVTYE 180

Query: 541 YPAWGYGIGWLMALSSMLCIPLWIFIKLWKTEGTLPEKLQKLTVP 585
           YP+W  G+GW M   S++ IPL +  ++   +G+  E+++ LT P
Sbjct: 181 YPSWAIGVGWSMVAMSIIFIPLVMVFRMLTADGSFVERVKHLTKP 315
>14638
          Length = 421

 Score = 81.3 bits (199), Expect = 1e-15,   Method: Compositional matrix adjust.
 Identities = 49/144 (34%), Positives = 73/144 (50%), Gaps = 6/144 (4%)
 Frame = -3

Query: 426 RRGYRRELLILALSIISYFLGLVMLTEGGMYIFQLFDSYAASGMCLLFVAIFECVCIGWV 485
           R  +R  +  +++  + + LGL   T+GG YI  L D +   G  LL V  FE V I WV
Sbjct: 419 RGKWRSIIFRVSMCALGFILGLPQTTQGGTYILDLLDIFV--GFPLLLVGFFEFVAIVWV 246

Query: 486 YGSNRFYDNIEDMIGYRPLSLI------KWCWKVVTPGICAGIFIFFLVKYKPLKYNNVY 539
           YG  R  +++  M+G  P++ +       W W VV+PG+   I +F  V Y P+      
Sbjct: 245 YGFRRISEDVMMMMGDHPITRMVYDFYFSWTWLVVSPGLLLAIIVFDSVNYVPITGPG-- 72

Query: 540 TYPAWGYGIGWLMALSSMLCIPLW 563
            YP W   +GWL+    M+ IP+W
Sbjct: 71  -YPPWAETLGWLVVTFIMMWIPVW 3
>21870
          Length = 347

 Score = 68.6 bits (166), Expect(2) = 9e-13,   Method: Compositional matrix adjust.
 Identities = 28/45 (62%), Positives = 36/45 (80%)
 Frame = -2

Query: 45  RGHWNNKVEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFLIPYVV 89
           R  W   +EF+++  G  +GLGNVWRFPYLCY+NGGGAFLIPY++
Sbjct: 199 RATWGRHLEFIVTCIGFAVGLGNVWRFPYLCYRNGGGAFLIPYLI 65

 Score = 23.1 bits (48), Expect(2) = 9e-13,   Method: Compositional matrix adjust.
 Identities = 10/16 (62%), Positives = 11/16 (68%)
 Frame = -3

Query: 95  GIPVFFLETALGQFTS 110
           GIP+F LE   GQF S
Sbjct: 48  GIPLFCLEITFGQFAS 1
>31151
          Length = 322

 Score = 52.4 bits (124), Expect = 6e-07,   Method: Compositional matrix adjust.
 Identities = 29/79 (36%), Positives = 45/79 (56%)
 Frame = -2

Query: 483 GWVYGSNRFYDNIEDMIGYRPLSLIKWCWKVVTPGICAGIFIFFLVKYKPLKYNNVYTYP 542
           GW+YG  R  ++I  M+G+ P  ++   WK +TP +   + +F L+ Y P  Y   Y Y 
Sbjct: 321 GWIYGVARIREDICLMLGHGPPFILTVFWKFITPALLLVVLVFTLMNYTPPSYGQ-YVYG 145

Query: 543 AWGYGIGWLMALSSMLCIP 561
             G+  GW++ALSS+L  P
Sbjct: 144 TGGHVFGWVVALSSLLPSP 88
>05476
          Length = 689

 Score = 29.3 bits (64), Expect = 5.4,   Method: Compositional matrix adjust.
 Identities = 24/73 (32%), Positives = 35/73 (47%), Gaps = 7/73 (9%)
 Frame = -2

Query: 542 PAWGYGIGWLMALSSM-----LCIPLWIFIKLWKTEGTLPEKLQKLTV--PSADLKMRGK 594
           P W  G   ++A+SS      LC+PLW+F+ L+ T       +Q L+   PS D      
Sbjct: 622 PRWDAGAS-VLAMSSFTVTL*LCLPLWVFMSLFFTIFHSACFIQSLSTISPSRDXXDN-- 452

Query: 595 LGASPRTVTVNDC 607
            GA P +  + DC
Sbjct: 451 -GAFPCSXXI*DC 416
>37391
          Length = 199

 Score = 28.5 bits (62), Expect = 8.1,   Method: Composition-based stats.
 Identities = 11/23 (47%), Positives = 16/23 (69%)
 Frame = +2

Query: 223 LALCLLAAWTICYFCIWKGTKST 245
           L  CL+A  ++CYF +WK  +ST
Sbjct: 119 LVFCLVAVSSVCYFFLWKEFRST 187
>04357
          Length = 1093

 Score = 28.5 bits (62), Expect = 8.1,   Method: Compositional matrix adjust.
 Identities = 12/28 (42%), Positives = 14/28 (50%)
 Frame = -3

Query: 155  NCFTTELPWATCGHEWNTEKCVEFQKLN 182
            N F T     TC H WN++K  E  K N
Sbjct: 1007 NQFPTHASTNTCKHSWNSQKTCEHSKHN 924
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31981690|ref|NP_112442.2| heat shock protein 8 [Mus
musculus]
         (646 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

30255                                                                 295   e-112
21024                                                                 224   1e-58
37715                                                                 152   2e-56
27378                                                                 200   2e-51
26390                                                                 168   6e-42
24750                                                                 141   1e-33
06909                                                                 100   4e-26
31218                                                                  95   7e-20
09881                                                                  89   6e-18
20979                                                                  83   3e-16
12271                                                                  62   5e-10
13684                                                                  56   4e-08
03996                                                                  51   2e-06
34036                                                                  48   1e-05
13300                                                                  46   6e-05
>30255
          Length = 1761

 Score =  295 bits (756), Expect(2) = e-112,   Method: Compositional matrix adjust.
 Identities = 150/199 (75%), Positives = 155/199 (77%)
 Frame = -1

Query: 328  KSQIHDIVLVGGSTRIPKIQKLLQDFFNGKELNKSINPDEXXXXXXXXXXXILSGDKSEN 387
            K  IH+IVLVGGSTRIPKIQKLLQDFFNGKEL KSINPDE           IL GDKSE 
Sbjct: 1644 KPGIHEIVLVGGSTRIPKIQKLLQDFFNGKELCKSINPDEAVAYGACVQAAILHGDKSEE 1465

Query: 388  VQDXXXXXXXXXXXGIETAGGVMTVLIKRNXXXXXXXXXXXXXYSDNQPGVLIQVYEGER 447
            VQD           GIETAGGVMT LIKRN             YSDNQPGVLIQVYEGER
Sbjct: 1464 VQDLLLLDVAPLSMGIETAGGVMTALIKRNTTIPTKQTQTFTTYSDNQPGVLIQVYEGER 1285

Query: 448  AMTKDNNLLGKFELTGIPPAPRGVPQIEVTFDIDANGILNVSAVDKSTGKENKITITNDK 507
            AMT+DNNLLGKFELTGIPPAPRGVPQIEVTFDIDANGILNVSA DKSTGKENKITITNDK
Sbjct: 1284 AMTRDNNLLGKFELTGIPPAPRGVPQIEVTFDIDANGILNVSAADKSTGKENKITITNDK 1105

Query: 508  GRLSKEDIERMVQEAEKYK 526
            GRLSKE+IERMV +AEK +
Sbjct: 1104 GRLSKEEIERMVNDAEKSR 1048

 Score =  128 bits (322), Expect(2) = e-112,   Method: Compositional matrix adjust.
 Identities = 58/79 (73%), Positives = 74/79 (93%)
 Frame = -3

Query: 534  DKVSSKNSLESYAFNMKATVEDEKLQGKINDEDKQKILDKCNEIISWLDKNQTAEKEEFE 593
            +++SSKNSLESYAF+MK+T+EDEK++ KI +EDK+ I+DKCNE+ISWLD NQTAEK+E++
Sbjct: 1027 NRISSKNSLESYAFHMKSTIEDEKIKDKIGEEDKKTIVDKCNEVISWLDANQTAEKDEYD 848

Query: 594  HQQKELEKVCNPIITKLYQ 612
             +QKELEKVCNPIITKLYQ
Sbjct: 847  DKQKELEKVCNPIITKLYQ 791
>21024
          Length = 3220

 Score =  224 bits (570), Expect = 1e-58,   Method: Compositional matrix adjust.
 Identities = 167/457 (36%), Positives = 242/457 (52%), Gaps = 22/457 (4%)
 Frame = +1

Query: 166  GLNVLRIINEPTAAAIA--YGL-----DKKVGAER----NVLIFDLGGGTFDVSILTIED 214
            G NVLR+INEPTAAA+A  +G      D  V   R    ++ + D  G        ++  
Sbjct: 727  G*NVLRVINEPTAAALALWHGQV*R*SDSGV*FRRRDV*HLYLGDPEG--------SV*S 882

Query: 215  GIFEVKSTAGDTHLGGEDFDNRMVNHFIAEFKRKHKKDISENKRAVRRLRTACERAKRTL 274
             I + +   G   L    +      +      RK K   S+  + + R     +++K  L
Sbjct: 883  QINQRRHIPGRRGLLTTTWSTSWHQNL-----RKSKD*TSQRIQWLCRDYVRQQKSKIEL 1047

Query: 275  SSSTQASIEIDSLYEGID------FYTSITRARFEELNADLFRGTLDPVEKALRDAKLDK 328
            SSS Q  I +   Y  +D          ++R++FE L   L + T+ P +KAL+DA++ K
Sbjct: 1048 SSSLQTDINLP--YLTMDASGPKHMNLKLSRSKFESLVESLVKRTVGPCQKALQDAEVKK 1221

Query: 329  SQIHDIVLVGGSTRIPKIQKLLQDFFNGKELNKSINPDEXXXXXXXXXXXILSGDKSENV 388
            S I +++LVGG +R+PK+Q  +QD F G+  +KS+NPDE           +L+GD    V
Sbjct: 1222 SDIGEVILVGGMSRMPKVQSTVQDLF-GRTPSKSVNPDEAVAIGAAIQGGVLAGD----V 1386

Query: 389  QDXXXXXXXXXXXGIETAGGVMTVLIKRNXXXXXXXXXXXXXYSDNQPGVLIQVYEGERA 448
             D           GIET GGV T LI RN              +D Q  V I+V++GER 
Sbjct: 1387 TDVLLLDVTPLSLGIETLGGVFTKLINRNTTIPTKKSQVFSTAADGQTQVEIKVHQGERE 1566

Query: 449  MTKDNNLLGKFELTGIPPAPRGVPQIEVTFDIDANGILNVSAVDKSTGKENKITITNDKG 508
            M  DN LLG+F L GIPPAPRGVPQ+EVTFDIDANGI+NVSA DK TGKE +I I +  G
Sbjct: 1567 MANDNKLLGQFTLVGIPPAPRGVPQVEVTFDIDANGIVNVSARDKGTGKEQQIVIQSSGG 1746

Query: 509  RLSKEDIERMVQEAEKYKAEDEKQRDKVSSKNSLESYAFNMKATVEDEKLQGKINDEDKQ 568
             LSK++IE M++ AE +  +D ++++ V   N  +S   + ++ +E+ K Q  +  E+  
Sbjct: 1747 -LSKDEIENMIKNAEAHAEDDRRKKELVEVLNQADSIIHDTESKMEEFKDQ--LPQEECD 1917

Query: 569  KILDKCNEIISWL--DKNQTAEK---EEFEHQQKELE 600
            K+ +K NE+   L    N+  EK   E  + QQK L+
Sbjct: 1918 KLREKINEVKQLLANKDNEAPEKIREETSDLQQKSLK 2028

 Score =  188 bits (477), Expect = 7e-48,   Method: Compositional matrix adjust.
 Identities = 115/269 (42%), Positives = 158/269 (58%), Gaps = 2/269 (0%)
 Frame = +3

Query: 3   KGPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFT-DTERLIGDAAKNQVAM 61
           KG  +GIDLGTT SCV + +  + +++ N +G+RTTPS +AFT D ER+ G  AK Q   
Sbjct: 243 KGHVIGIDLGTTNSCVALMEGKQAKVLENSEGSRTTPSVIAFTKDGERISGMPAKRQAVT 422

Query: 62  NPTNTVFDAKRLIGRRFDDAVVQSDMKHWPFMVVNDAGRPKVQVEYKGETKSFYPEEVSS 121
           N  NT+   KRLIGRRF+D  VQ DMK+  + +V  A      VE +G  K + P +V +
Sbjct: 423 NAENTLSATKRLIGRRFEDPEVQKDMKNVSYKIVK-ASNGDAWVEAQG--KMYSPSQVGA 593

Query: 122 MVLTKMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAI 181
            VL KMKE AE+YLG  V NAVVTVPAYFNDSQRQATKDAG I+GL  +       + + 
Sbjct: 594 FVLMKMKETAESYLGSKVNNAVVTVPAYFNDSQRQATKDAGQISGLKCVACDQRTHSCSS 773

Query: 182 AYGLDKKVGAERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGE-DFDNRMVNH 240
            +     +  +    +    G    +S  +  + +   + T  +TH   E  FDN MVN 
Sbjct: 774 CFMAWTSLKIK**RCLI*AEGRLTSLSWRSRRECLKSNQPT--ETHSWEERTFDNYMVNF 947

Query: 241 FIAEFKRKHKKDISENKRAVRRLRTACER 269
             +EFK++   DI+++  AV+RLR A E+
Sbjct: 948 LASEFKKEQGLDITKDPMAVQRLREAAEK 1034
>37715
          Length = 468

 Score =  152 bits (384), Expect(2) = 2e-56,   Method: Compositional matrix adjust.
 Identities = 71/97 (73%), Positives = 84/97 (86%)
 Frame = -2

Query: 94  VVNDAGRPKVQVEYKGETKSFYPEEVSSMVLTKMKEIAEAYLGKTVTNAVVTVPAYFNDS 153
           V+N + +P +Q    G TK+F PEE+S+MVL KM++IAEAYLGK + NAVVTVPAYFND+
Sbjct: 452 VINKSNKPHIQALVSGATKTFAPEEISAMVLGKMRDIAEAYLGKKIDNAVVTVPAYFNDA 273

Query: 154 QRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKVG 190
           QRQATKDAGTIAGLNV+RIINEPTAAAIAYGLDK+ G
Sbjct: 272 QRQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKRDG 162

 Score = 85.5 bits (210), Expect(2) = 2e-56,   Method: Composition-based stats.
 Identities = 36/49 (73%), Positives = 46/49 (93%)
 Frame = -1

Query: 194 NVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNHFI 242
           N+L+FDLGGGTFDVS+LTI++G+FEV +T GDTHLGGEDFD R+++HFI
Sbjct: 156 NILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMDHFI 10
>27378
          Length = 410

 Score =  200 bits (508), Expect = 2e-51,   Method: Compositional matrix adjust.
 Identities = 96/124 (77%), Positives = 107/124 (86%)
 Frame = -1

Query: 244 EFKRKHKKDISENKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGIDFYTSITRARFE 303
           EFKRK+KKD+  N RA+RRLRTA ERAKRTLSSST+A+IE+D+L+EG DFYT I+RARFE
Sbjct: 410 EFKRKYKKDLRSNPRALRRLRTAAERAKRTLSSSTEATIEVDALFEGHDFYTKISRARFE 231

Query: 304 ELNADLFRGTLDPVEKALRDAKLDKSQIHDIVLVGGSTRIPKIQKLLQDFFNGKELNKSI 363
           EL ADLFR TL PVEKAL DAK+DK  IHDIVLVGGSTRIPK+Q LLQ FF GK LN SI
Sbjct: 230 ELCADLFRQTLAPVEKALNDAKMDKQMIHDIVLVGGSTRIPKVQNLLQQFFGGKSLNLSI 51

Query: 364 NPDE 367
           NPDE
Sbjct: 50  NPDE 39
>26390
          Length = 665

 Score =  168 bits (426), Expect = 6e-42,   Method: Compositional matrix adjust.
 Identities = 84/154 (54%), Positives = 102/154 (66%)
 Frame = +2

Query: 402 GIETAGGVMTVLIKRNXXXXXXXXXXXXXYSDNQPGVLIQVYEGERAMTKDNNLLGKFEL 461
           GIET GGVMT LI R                DNQ  V IQVYEGER+ TKDN+LLG+F+L
Sbjct: 50  GIETVGGVMTTLIARGTTIPARKAKVFSTAQDNQDSVTIQVYEGERSRTKDNHLLGRFDL 229

Query: 462 TGIPPAPRGVPQIEVTFDIDANGILNVSAVDKSTGKENKITITNDKGRLSKEDIERMVQE 521
           TGIP APRGVPQIEVTF +DANG++ VSA DK TG++N I I      LS ED+ERMVQE
Sbjct: 230 TGIPAAPRGVPQIEVTFQVDANGVMQVSAEDKGTGQKNDIIIQQSGSGLSPEDVERMVQE 409

Query: 522 AEKYKAEDEKQRDKVSSKNSLESYAFNMKATVED 555
           A+ +  ED K R+   S+  LES A+  +  ++D
Sbjct: 410 AQDFAEEDRKFRELTESRTGLESLAYTAQHQLQD 511
>24750
          Length = 552

 Score =  141 bits (355), Expect = 1e-33,   Method: Compositional matrix adjust.
 Identities = 66/71 (92%), Positives = 70/71 (98%)
 Frame = +1

Query: 439 LIQVYEGERAMTKDNNLLGKFELTGIPPAPRGVPQIEVTFDIDANGILNVSAVDKSTGKE 498
           ++QVYEGERAMT+DNNLLGKFELTGIPPAPRGVPQIEVTFDIDANGILNVSA DKSTGKE
Sbjct: 154 MLQVYEGERAMTRDNNLLGKFELTGIPPAPRGVPQIEVTFDIDANGILNVSAADKSTGKE 333

Query: 499 NKITITNDKGR 509
           NKITITNDKG+
Sbjct: 334 NKITITNDKGQ 366
>06909
          Length = 456

 Score =  100 bits (249), Expect(2) = 4e-26,   Method: Compositional matrix adjust.
 Identities = 44/66 (66%), Positives = 59/66 (89%)
 Frame = -3

Query: 547 FNMKATVEDEKLQGKINDEDKQKILDKCNEIISWLDKNQTAEKEEFEHQQKELEKVCNPI 606
            +MK+T+EDEK++ KI+ EDK+ ILDKC+E+I+WLD NQ AEK+E++ +QKE+EKVCNPI
Sbjct: 388 LHMKSTIEDEKIKDKISTEDKKTILDKCDEVIAWLDANQLAEKDEYDDKQKEIEKVCNPI 209

Query: 607 ITKLYQ 612
           ITKLYQ
Sbjct: 208 ITKLYQ 191

 Score = 36.2 bits (82), Expect(2) = 4e-26,   Method: Compositional matrix adjust.
 Identities = 16/23 (69%), Positives = 21/23 (91%)
 Frame = -1

Query: 524 KYKAEDEKQRDKVSSKNSLESYA 546
           KYK +DEKQ+ ++S+KNSLESYA
Sbjct: 456 KYKEDDEKQKSRISAKNSLESYA 388
>31218
          Length = 322

 Score = 95.1 bits (235), Expect = 7e-20,   Method: Compositional matrix adjust.
 Identities = 47/100 (47%), Positives = 68/100 (68%)
 Frame = +2

Query: 225 DTHLGGEDFDNRMVNHFIAEFKRKHKKDISENKRAVRRLRTACERAKRTLSSSTQASIEI 284
           DTHLGGEDFD R+V++ +   K+K  +D+  + RA+ RLR + E+AKR LSS     +++
Sbjct: 2   DTHLGGEDFDQRLVDYLVKLIKQKTGRDVRHDTRAMSRLRRSAEKAKRALSSQHSTKVDL 181

Query: 285 DSLYEGIDFYTSITRARFEELNADLFRGTLDPVEKALRDA 324
           D +   +   T +TRA+FEELN DLFR TL  V++AL D+
Sbjct: 182 DGVTSDLADLT-LTRAKFEELNTDLFRSTLTTVKRALEDS 298
>09881
          Length = 600

 Score = 89.0 bits (219), Expect = 6e-18,   Method: Composition-based stats.
 Identities = 44/109 (40%), Positives = 64/109 (58%)
 Frame = +3

Query: 3   KGPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMN 62
           K  A G+ LGT  +C+ V++ GK  + AND G+R+TP  VAFT  +  +G +AK  +  N
Sbjct: 177 KMAAYGVHLGTCSACLAVYKDGKTSVAANDAGDRSTPCVVAFTACDAEVGASAKQGIVSN 356

Query: 63  PTNTVFDAKRLIGRRFDDAVVQSDMKHWPFMVVNDAGRPKVQVEYKGET 111
             NTV + KR++G  F+D V Q  +   P  VVN   +P  +VE+K  T
Sbjct: 357 VKNTVCNVKRILGLTFEDPVTQEYLASSPVKVVNQKNQPMFEVEFKERT 503

 Score = 49.7 bits (117), Expect = 3e-06,   Method: Composition-based stats.
 Identities = 27/54 (50%), Positives = 37/54 (68%)
 Frame = +2

Query: 136 GKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKV 189
           GK + +AV+ VP+ F+D QR A   A + AG  VLR+INE +AAA+AY L + V
Sbjct: 2   GKGIQDAVLAVPSDFSDKQRAAASAAASKAGFKVLRLINECSAAALAYDLGQTV 163
>20979
          Length = 976

 Score = 83.2 bits (204), Expect = 3e-16,   Method: Compositional matrix adjust.
 Identities = 45/140 (32%), Positives = 79/140 (56%), Gaps = 2/140 (1%)
 Frame = +1

Query: 230 GEDFDNRMVNHFIAEFKRKHKKD--ISENKRAVRRLRTACERAKRTLSSSTQASIEIDSL 287
           G +   R+ +H    F  + K+   + +N RA+ +L    ER K+ LS+++    +++ L
Sbjct: 70  GVEMTLRLRDHLAKVFNGQKKRSFKLEDNPRAMAKLLKEAERVKKVLSANSDHKAQVEGL 249

Query: 288 YEGIDFYTSITRARFEELNADLFRGTLDPVEKALRDAKLDKSQIHDIVLVGGSTRIPKIQ 347
            EG DF   ++R  + EL  DL      P+E AL+ +++   +I +I+L+GG +R+P++Q
Sbjct: 250 VEGEDFAAKVSREDYLELIKDLLARVTKPMEDALKVSEITMPEITEIILMGGGSRVPRVQ 429

Query: 348 KLLQDFFNGKELNKSINPDE 367
           + L  F    +L KSIN DE
Sbjct: 430 EELLKFSGKSDLGKSINTDE 489
>12271
          Length = 1762

 Score = 62.4 bits (150), Expect = 5e-10,   Method: Compositional matrix adjust.
 Identities = 29/76 (38%), Positives = 48/76 (63%)
 Frame = +2

Query: 292 DFYTSITRARFEELNADLFRGTLDPVEKALRDAKLDKSQIHDIVLVGGSTRIPKIQKLLQ 351
           DF   +TR ++  L  DL      PV++ L  +++  ++I +I+L+GG +R+PKI ++L 
Sbjct: 41  DFSCKVTRDKYLHLIQDLLDRVTLPVQQVLTASQITWAEITEIILMGGGSRLPKIHEILL 220

Query: 352 DFFNGKELNKSINPDE 367
           D+   KEL KS+N DE
Sbjct: 221 DYSGKKELGKSLNTDE 268

 Score = 32.7 bits (73), Expect = 0.49,   Method: Compositional matrix adjust.
 Identities = 26/121 (21%), Positives = 52/121 (42%), Gaps = 3/121 (2%)
 Frame = +1

Query: 487  NVSAVDKSTGKENKITIT---NDKGRLSKEDIERMVQEAEKYKAEDEKQRDKVSSKNSLE 543
            N  A     G   K+ +T    D   LSK+ +++  +    ++  DE++     ++N +E
Sbjct: 937  NKKAASAGKGFNEKLKVTVKVKDMAELSKDQVKQSKKRLTDWRKRDEEKAAVQKARNEVE 1116

Query: 544  SYAFNMKATVEDEKLQGKINDEDKQKILDKCNEIISWLDKNQTAEKEEFEHQQKELEKVC 603
            S+    +  + +E       DE++  ILD+ ++   WL +     K+ F     E    C
Sbjct: 1117 SFIITAQDKMSEETYLASSTDEERAXILDQLSQASDWLYEQSHQAKKWFSPTNTET*GTC 1296

Query: 604  N 604
            +
Sbjct: 1297 S 1299
>13684
          Length = 438

 Score = 56.2 bits (134), Expect = 4e-08,   Method: Composition-based stats.
 Identities = 25/60 (41%), Positives = 37/60 (61%)
 Frame = -3

Query: 3   KGPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMN 62
           K  A G+ LGT  +C+ V++ GK  + AND G+R+TP  VAFT  +  +G +AK  +  N
Sbjct: 181 KMAAYGVHLGTCSACLAVYKDGKTSVAANDAGDRSTPCVVAFTACDAEVGASAKQGIVSN 2
>03996
          Length = 1105

 Score = 50.8 bits (120), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 25/64 (39%), Positives = 40/64 (62%)
 Frame = -2

Query: 304  ELNADLFRGTLDPVEKALRDAKLDKSQIHDIVLVGGSTRIPKIQKLLQDFFNGKELNKSI 363
            EL  DL      P+E AL+ +++   +I +I+L+GG +R+P++Q+ L  F    +L KSI
Sbjct: 1056 ELIKDLLARVTKPMEDALKVSEITMPEITEIILMGGGSRVPRVQEELLKFSGKSDLGKSI 877

Query: 364  NPDE 367
            N DE
Sbjct: 876  NTDE 865
>34036
          Length = 363

 Score = 48.1 bits (113), Expect = 1e-05,   Method: Composition-based stats.
 Identities = 19/25 (76%), Positives = 24/25 (96%)
 Frame = +2

Query: 588 EKEEFEHQQKELEKVCNPIITKLYQ 612
           EK+E++ +QKE+EKVCNPIITKLYQ
Sbjct: 2   EKDEYDDKQKEIEKVCNPIITKLYQ 76
>13300
          Length = 453

 Score = 45.8 bits (107), Expect = 6e-05,   Method: Compositional matrix adjust.
 Identities = 32/149 (21%), Positives = 72/149 (48%), Gaps = 17/149 (11%)
 Frame = +3

Query: 154 QRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKVG---AERNVLIFDLGGGTFDVSIL 210
           +R+A   A    G+NVL+++ +  A A+ YG+ ++       +  + +D+G  +   +++
Sbjct: 3   ERRAIMTAADXVGINVLQLMTDSAAVALNYGVFRRKNFNTTAQYYMFYDMGATSTVATVV 182

Query: 211 T-----IEDGI-------FEVKSTAGDTHLGGEDFDNRMVNHFIAEFKRKHKKD--ISEN 256
           +     +++G          +K    D  LGG +   R+ +H    F  + K+   + +N
Sbjct: 183 SYQVVKVKEGTRVESNPQLTIKGVGFDRTLGGLEMTLRLRDHLAKVFNGQKKRSFKLEDN 362

Query: 257 KRAVRRLRTACERAKRTLSSSTQASIEID 285
            RA+ +L    ER K+ LS+++    +++
Sbjct: 363 PRAMAKLLKEAERVKKVLSANSDHKAQVE 449
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|54261793|ref|NP_998781.1| plasma membrane calcium
ATPase 4 [Mus musculus]
         (1205 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

12151                                                                 276   e-112
06342                                                                 262   6e-70
29829                                                                 223   3e-58
00499                                                                 207   2e-53
21541                                                                 146   4e-35
36566                                                                 129   1e-29
35407                                                                 110   2e-28
08160                                                                  67   4e-11
28890                                                                  59   9e-09
14773                                                                  59   9e-09
04985                                                                  53   7e-07
33697                                                                  43   8e-04
13525                                                                  43   9e-04
14321                                                                  40   0.007
07486                                                                  39   0.015
32708                                                                  30   6.0  
26294                                                                  30   6.4  
>12151
          Length = 880

 Score =  276 bits (707), Expect(2) = e-112,   Method: Compositional matrix adjust.
 Identities = 144/198 (72%), Positives = 167/198 (84%), Gaps = 4/198 (2%)
 Frame = +3

Query: 795 KKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNVV 854
           +KADVGFAMGI+GTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSI+KFLQFQLTVNVV
Sbjct: 288 QKADVGFAMGISGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSIAKFLQFQLTVNVV 467

Query: 855 AVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLLRRRPYGRNKPLIS 914
           AV VAF GAC   DSPLKA+QMLWVNLIMDT ASLALATE P+  LL+RRPYGR KPLIS
Sbjct: 468 AVFVAFVGACSIGDSPLKAIQMLWVNLIMDTLASLALATELPSSELLKRRPYGRTKPLIS 647

Query: 915 RTMMKNILGHAVYQLLIVFLLVFAG-DTLFDID---SGRKAPLNSPPSQHYTIVFNTFVL 970
           +TM KNILGHA YQ+L++ LL+F G   ++D     + R+ P   P +QH+TI+FN FV+
Sbjct: 648 KTMWKNILGHAFYQILVILLLLFQGAKAVWDRRWHPTSRETP--RPTNQHFTIIFNAFVM 821

Query: 971 MQLFNEINARKIHGEKNV 988
           M LFNE+NARKIH ++N+
Sbjct: 822 MTLFNEVNARKIHDQRNI 875

 Score =  150 bits (378), Expect(2) = e-112,   Method: Compositional matrix adjust.
 Identities = 71/98 (72%), Positives = 82/98 (83%)
 Frame = +1

Query: 699 DNVNTARAIATKCGILTPKDDFLCLEGKEFNSLIRNEKGEVEQEKLDKIWPKLRVLARSS 758
           DNVNTAR+IA+KCGI+ P DD L LEGKEFN LIR+ +GE+ QEK+D++WP LRVLARSS
Sbjct: 1   DNVNTARSIASKCGIIQPGDDGLVLEGKEFNQLIRDAEGEISQEKVDEVWPNLRVLARSS 180

Query: 759 PTDKHTLVKGIIDSTAGEQRQVVAVTGDGTNDGPALKK 796
           P DK+ LVK IIDS     R+VVAVTGDGTNDGPALKK
Sbjct: 181 PQDKYILVKHIIDSKVSTSREVVAVTGDGTNDGPALKK 294
>06342
          Length = 2428

 Score =  262 bits (670), Expect = 6e-70,   Method: Compositional matrix adjust.
 Identities = 236/781 (30%), Positives = 357/781 (45%), Gaps = 59/781 (7%)
 Frame = +2

Query: 206 IVVGDIAQIKYGDLLPADG--ILIQGNDLKIDESSLTGESDHVKKTLDKDP--------- 254
           +V GDI ++  GD +PAD   + I    L+ID++ LTGES  V K  D  P         
Sbjct: 5   LVPGDIVEVSVGDKVPADIRILKIHSTTLRIDQAILTGESVSVMKHTDPIPDPRAVNQDK 184

Query: 255 --MLLSGTHVMEGSGRMVVTAVGVNSQTGIIFTLLGASXXXXXXXXXXXXXXQGAPENRN 312
             +L SGT+V  G  + +V   G+ ++ G I                           RN
Sbjct: 185 KNLLFSGTNVAAGKCKGLVIGTGLTTEIGKI---------------------------RN 283

Query: 313 KAKTQDGVALEIQPLNSQEGLDSEDKEKKIARIPKKEKSVLQGKLTRLAVQIGKAGLIMS 372
                             E +D+E           +EK+ LQ KL   + Q+ K   I+ 
Sbjct: 284 ------------------EMMDTE-----------QEKTPLQQKLDEFSNQLSKVITIIC 376

Query: 373 VLTVVILILYFVVDNFVIQRREWLPECTPVYIQYFVKFFIIGVTVLVVAVPEGLPLAVTI 432
           +    I I +F   N       W        I+  + +F I V + V A+PEGLP  +T 
Sbjct: 377 IAVWAINIGHF---NDPAHGGSW--------IKGAIYYFKIAVALAVAAIPEGLPAVITT 523

Query: 433 SLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTMNRMTVVQAYIGG---THYR 489
            LA   ++M K N +VR L + ET+G  + ICSDKTGTLT N+M+V + +I     T+  
Sbjct: 524 CLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCKLFIFSQIDTNQI 703

Query: 490 QIPQPDV----FPPKVLELIVNGISIN-------------CAYTSKIQPPEKEGGLP-RQ 531
           +  Q +V    + P   EL  NG  +              C   +       E      +
Sbjct: 704 KTTQFEVTGSTYAPDG-ELYQNGKKVKASDYPGLEELCTICGMCNDSSVDYNEAKTQYEK 880

Query: 532 VGNKTECGLLGFVTDL-----------KQDYQAVRNEVPEEKLFKVYT--FNSVRKSMST 578
           VG  TE  L      L           K++   V N V ++   K +T  F+  RKSMS 
Sbjct: 881 VGEATETALTVLAEKLNFYNTDKSSLNKREMGTVCNHVIQDMWRKEFTLEFSRDRKSMSV 1060

Query: 579 --VIRKPE---GGFRMFSKGASEIMLRRCDRILNKEGEIKSFRSKDRDNMVRNVIEPMAS 633
             V  KP    GG RMF+KGA E +L RC  +     ++    +   + M    I     
Sbjct: 1061FCVPNKPTRVPGGARMFAKGAPEGLLDRCTHVRIGNNKVPMSPAIKNEIMKLTKIYGTGR 1240

Query: 634 EGLRTICLAYRDFDGTEPSWDIEG-----EILTSLICIAVVGIEDPVRPEVPDAIAKCKR 688
           + LR + LA  D        D+E      E  T++  + VVG+ DP R EV  +I  C+ 
Sbjct: 1241DTLRCLALATIDNPPRREDMDLEDSRKFIEYETNMTFVGVVGMLDPPREEVMASIKNCRA 1420

Query: 689 AGITVRMVTGDNVNTARAIATKCGILTPKDDF--LCLEGKEFNSLIRNEKGEVEQEKLDK 746
           AGI V ++TGDN  TA AI  + G+ +  ++   L   G+EF+        E+  E    
Sbjct: 1421AGIRVIVITGDNKATAEAICRRIGVFSESENTEGLAYTGREFD--------ELPPEDQRA 1576

Query: 747 IWPKLRVLARSSPTDKHTLVKGIIDSTAGEQRQVVAVTGDGTNDGPALKKADVGFAMGIA 806
              + R+ AR  P  K  +V+ +       + ++ A+TGDG ND PALKKA++G AMG +
Sbjct: 1577AVMRARLFARVEPAHKSKIVEYL-----QAEGEISAMTGDGVNDAPALKKAEIGIAMG-S 1738

Query: 807 GTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACIT 866
           GT VAK AS+++L DDNF++IV AV  GR +Y+++ +F+++ ++ N+  V+  F  A + 
Sbjct: 1739GTAVAKSASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNIGEVVCIFLTAALG 1918

Query: 867 QDSPLKAVQMLWVNLIMDTFASLALATEPPTESLLRRRPYGRNKPLISRTMMKNILGHAV 926
               L  VQ+LWVNL+ D F + AL   PP   ++++ P    + LI+  +    +   +
Sbjct: 1919IPEALIPVQLLWVNLVTDGFPATALGFNPPDLDIMQKPPRNPREGLITGWLFFRYMAIGI 2098

Query: 927 Y 927
           Y
Sbjct: 2099Y 2101
>29829
          Length = 465

 Score =  223 bits (569), Expect = 3e-58,   Method: Compositional matrix adjust.
 Identities = 115/150 (76%), Positives = 131/150 (87%)
 Frame = -3

Query: 799 VGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIV 858
           +GFAMGI+GTDVAKEASDIILTDDNFTSIVKAV WGRNVYDSI+KFLQFQLTVNVVAV V
Sbjct: 460 LGFAMGISGTDVAKEASDIILTDDNFTSIVKAVXWGRNVYDSIAKFLQFQLTVNVVAVFV 281

Query: 859 AFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLLRRRPYGRNKPLISRTMM 918
           AF GAC   DSPL+A+QMLWVNLIMDT ASLALATE P+  LL+R+PYGR KPLIS+TM 
Sbjct: 280 AFVGACSIGDSPLEAIQMLWVNLIMDTLASLALATELPSNELLKRKPYGRTKPLISKTMF 101

Query: 919 KNILGHAVYQLLIVFLLVFAGDTLFDIDSG 948
           KNI GH+VYQ++I+ +++F G  LF ID G
Sbjct: 100 KNIAGHSVYQIIIILVILFKGADLFGIDDG 11
>00499
          Length = 4026

 Score =  207 bits (527), Expect = 2e-53,   Method: Compositional matrix adjust.
 Identities = 174/541 (32%), Positives = 269/541 (49%), Gaps = 60/541 (11%)
 Frame = +2

Query: 425 GLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTMNRMTVVQAYIG 484
           GL   VT+ L  + K+M + N LV++L+A ET+G+ + ICSDKTGTLT NRMTV   +  
Sbjct: 2   GLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFD 181

Query: 485 G--------------THYRQIPQPDVFPPKVLELIVNGISINCAYTSKIQPPEKEGGLPR 530
           G              T+ R  P           + ++ +++ C         +    L R
Sbjct: 182 GRIVEADTSDDQSNATYSRSDPT---------WMALSRVAMLCNRAEFKGNQDNVPILKR 334

Query: 531 QV-GNKTECGLL-------GFVTDLKQDYQAVRNEVPEEKLFKVYTFNSVRKSMSTV--I 580
           +  G+ +E  LL       G VT+ ++     RNE    K+ ++  FNS  K   ++   
Sbjct: 335 ECNGDASESALLKCVELSIGHVTEYRR-----RNE----KIVEI-PFNSSNKYQVSIHET 484

Query: 581 RKPEG-GFRMFSKGASEIMLRRCDRILNKEGEIKSFRSKDRDNMVRNVIEPMASEGLRTI 639
             P+   + +  KGA E ++ RC  IL   G+ +      R+      +E +   G R +
Sbjct: 485 EDPDDPRYLLVMKGAPERIMDRCSTIL-LNGKEQPLDDNFREAFNAAYLE-LGGLGERVL 658

Query: 640 --CLAYRDFDGTEPSWDIEGE----ILTSLICIAVVGIEDPVRPEVPDAIAKCKRAGITV 693
             C  +   D   P ++ + E     +T L  + ++ + DP R  VPDA+ KC+ AGI V
Sbjct: 659 GFCDYFLPVDQFPPGYEFDPEGPNFPITGLRFVGLMAMIDPPRAAVPDAVGKCRSAGIKV 838

Query: 694 RMVTGDNVNTARAIATKCGILTPKDDFLCLEGKEFNSLIRNEKG---------------- 737
            MVTGD+  TA+AIA   GI++        EG +    I +E+G                
Sbjct: 839 IMVTGDHPITAKAIARGVGIIS--------EGSKTVEDIASERGIPVEEVDPREAKAAVI 994

Query: 738 ------EVEQEKLDKIWPKLR-----VLARSSPTDKHTLVKGIIDSTAGEQRQVVAVTGD 786
                 ++   ++D+I   LR     V AR+SP  K  +V+G        Q Q+VAVTGD
Sbjct: 995 HGGDLRDMTPAQIDEI---LRNHSEIVFARTSPQQKLIIVEG-----CQRQGQIVAVTGD 1150

Query: 787 GTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQ 846
           G ND PALKKAD+G AMGIAG+DV+K+A+D+IL DDNF SIV  V  GR ++D++ K + 
Sbjct: 1151GVNDSPALKKADIGVAMGIAGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIA 1330

Query: 847 FQLTVNV--VAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLLRRR 904
           + LT N+  ++  + F  A I    PL  + +L ++L  D   +++LA E     +++R+
Sbjct: 1331YTLTSNIPEISPFLLFILADIPL--PLGTITILCIDLGTDMVPAISLAYEKAENDIMKRQ 1504

Query: 905 P 905
           P
Sbjct: 1505P 1507
>21541
          Length = 445

 Score =  146 bits (369), Expect = 4e-35,   Method: Compositional matrix adjust.
 Identities = 74/123 (60%), Positives = 88/123 (71%)
 Frame = +3

Query: 168 FNDWSKEKQFRGLQSRIELEQKFSIIRNGQLIQLPVAEIVVGDIAQIKYGDLLPADGILI 227
           FNDWSKEKQFRGLQS+IE E +F++IRNG+L Q+PV EI+VG+I QIKYGDLLPADG++I
Sbjct: 60  FNDWSKEKQFRGLQSKIEHEHRFTVIRNGELHQIPVGEILVGEICQIKYGDLLPADGVII 239

Query: 228 QGNDLKIDESSLTGESDHVKKTLDKDPMLLSGTHVMEGSGRMVVTAVGVNSQTGIIFTLL 287
           Q NDLK     +       +K   + P          G  +MVVTAVGVNSQTGIIF LL
Sbjct: 240 QSNDLKNRREFVNRRVGPCEKGRGQGPHAFVRHPCNGGQWKMVVTAVGVNSQTGIIFALL 419

Query: 288 GAS 290
           GAS
Sbjct: 420 GAS 428
>36566
          Length = 589

 Score =  129 bits (323), Expect = 1e-29,   Method: Compositional matrix adjust.
 Identities = 59/147 (40%), Positives = 100/147 (68%)
 Frame = +3

Query: 780 VVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYD 839
           VV +TGDG ND  ALK A++G +MG++GTDV+KEASD+IL DD+FT+I+ A+  G+ ++ 
Sbjct: 126 VVGMTGDGVNDAVALKSAEIGISMGVSGTDVSKEASDMILVDDDFTTILNAIEEGKGIFY 305

Query: 840 SISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTES 899
           +I  F++FQL+ ++ A+ +      +   +PL A+Q+LW+N+IMD   + +L  EP    
Sbjct: 306 NIRNFVRFQLSTSIAALSLIAVSTLLRLPNPLNAMQILWINIIMDGPPAQSLGVEPVDHD 485

Query: 900 LLRRRPYGRNKPLISRTMMKNILGHAV 926
           ++++ P     P+I+R ++ N+L  A+
Sbjct: 486 VIKQPPRHVGDPIITRRLIINVLSSAL 566
>35407
          Length = 562

 Score =  110 bits (276), Expect(2) = 2e-28,   Method: Compositional matrix adjust.
 Identities = 66/158 (41%), Positives = 83/158 (52%), Gaps = 1/158 (0%)
 Frame = +1

Query: 57  RLKTSPIEGLSGNPADLEKRRLVFGKNVIPPKRPKTFLELVWEALQDVTXXXXXXXXXXX 116
           +LKTSP EGL G+    E+ R  +G NVIPPK PK+FL LVWEALQDVT           
Sbjct: 91  KLKTSPTEGLVGDLGKEERVRF-YGSNVIPPKPPKSFLRLVWEALQDVTLLILIVAAIIS 267

Query: 117 XXXXFYR-PPGGDNEICGHIASSPXXXXXXXXXXXXXXXXXXXXXXXXXXXXFNDWSKEK 175
               FY+     D        +                              FNDWSKEK
Sbjct: 268 LGLSFYKGDEEEDETEDESYRAKADSSLEEKVGWIDGLAILVAVAVVVLVTAFNDWSKEK 447

Query: 176 QFRGLQSRIELEQKFSIIRNGQLIQLPVAEIVVGDIAQ 213
           QFRGLQS+IE E +F++IR+G+L Q+PV +I+VG+I Q
Sbjct: 448 QFRGLQSKIEHEHRFTVIRDGELHQIPVGDILVGEICQ 561

 Score = 34.7 bits (78), Expect(2) = 2e-28,   Method: Composition-based stats.
 Identities = 16/38 (42%), Positives = 23/38 (60%)
 Frame = +2

Query: 28 DLRKLMELRGADAVAQISAHYGGVQEICTRLKTSPIEG 65
          +LR+LME R  +A   I+  YGGV E+C   K  P++ 
Sbjct: 5  ELRELMEHRSHEAYNIIATKYGGVLEMCKS*KRHPLKA 118
>08160
          Length = 459

 Score = 67.4 bits (163), Expect = 4e-11,   Method: Compositional matrix adjust.
 Identities = 31/61 (50%), Positives = 42/61 (68%)
 Frame = +2

Query: 425 GLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTMNRMTVVQAYIG 484
           GL   VT+ L  + K+M + N LV++L+A ET+G+ + ICSDKTGTLT NRMTV   +  
Sbjct: 2   GLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFD 181

Query: 485 G 485
           G
Sbjct: 182 G 184
>28890
          Length = 552

 Score = 59.3 bits (142), Expect = 9e-09,   Method: Compositional matrix adjust.
 Identities = 39/128 (30%), Positives = 68/128 (53%), Gaps = 9/128 (7%)
 Frame = -3

Query: 168 FNDWSKEKQFRGLQSRIELEQKFSII-RNGQLIQLPVAEIVVGDIAQIKYGDLLPADGIL 226
           F+ + + K  + + S   L  +F+++ R  Q + +   E+VVGDI + K+GD +PAD  +
Sbjct: 538 FSYYQEAKSSKIMDSFKNLVPQFAVVVRGDQKLSVKAEELVVGDIVECKFGDRVPADLRV 359

Query: 227 IQGNDLKIDESSLTGESDHVKKT--------LDKDPMLLSGTHVMEGSGRMVVTAVGVNS 278
           I  +  K+D SSLTGES+   ++        L+   +    T+ +EG+ R +V   G ++
Sbjct: 358 ISAHGFKVDNSSLTGESEPQSRSAEFTHENPLETRNICFFSTNAVEGTCRGIVIKTGDDT 179

Query: 279 QTGIIFTL 286
             G I  L
Sbjct: 178 VMGRIANL 155
>14773
          Length = 794

 Score = 59.3 bits (142), Expect = 9e-09,   Method: Compositional matrix adjust.
 Identities = 34/117 (29%), Positives = 63/117 (53%)
 Frame = +2

Query: 808 TDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQ 867
           +DV+K+A+D+IL DDNF SIV  V  GR ++D++ K + + LT N+  +           
Sbjct: 2   SDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEISPFLVYILFGT 181

Query: 868 DSPLKAVQMLWVNLIMDTFASLALATEPPTESLLRRRPYGRNKPLISRTMMKNILGH 924
             PL  + +L+++L  D   +++LA E     +++R P   +  L++  ++    G 
Sbjct: 182 PLPLGVITILFIDLGTDMVPAISLAYEMAESDIMKRPPRTISDRLVNERLIAMSYGQ 352
>04985
          Length = 1671

 Score = 53.1 bits (126), Expect = 7e-07,   Method: Compositional matrix adjust.
 Identities = 57/205 (27%), Positives = 92/205 (44%), Gaps = 11/205 (5%)
 Frame = -1

Query: 742  EKLDKIWPKLRVLARSSPTDKHTLVKGIIDSTAGEQRQVVAVTGDGTNDGPALKKADVGF 801
            E L K+  +  V AR +P  K  L++ +          +V + GDG ND  ALK A  G 
Sbjct: 1641 ELLPKVCTQGTVFARMAPDQKCALIENL-----QSYDYIVGMCGDGANDCEALKAAHAGI 1477

Query: 802  AMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNV---------YDSISKFLQFQLTVN 852
            ++  A   VA   +  I   +N   +V A+  GR           Y ++  F+QF     
Sbjct: 1476 SLSEAEASVAAPFTSRI---NNIECVVTAMREGRAALVTSFGCFKYMALYSFIQF----- 1321

Query: 853  VVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLLRRRPYGRNKPL 912
             ++V++ +T  C T  S L   + L+++LI+ T  ++ L      + L+R +P      L
Sbjct: 1320 -ISVLILYT--CQTNLSDL---EFLYIDLIITTTIAVLLGYTGAYDKLVRHKPPDSLMKL 1159

Query: 913  --ISRTMMKNILGHAVYQLLIVFLL 935
              I   +M+  L  A YQL  +F L
Sbjct: 1158 SNIISILMQVTLT-AAYQLSTLFYL 1087
>33697
          Length = 310

 Score = 42.7 bits (99), Expect = 8e-04,   Method: Composition-based stats.
 Identities = 25/58 (43%), Positives = 31/58 (53%)
 Frame = -2

Query: 649 TEPSWDIEGEILTSLICIAVVGIEDPVRPEVPDAIAKCKRAGITVRMVTGDNVNTARA 706
           T PS D       S+I        DP R  VPDA+ KC+ AGI V MVTGD+  T++ 
Sbjct: 243 TSPSLDSASSASWSMI--------DPPRAAVPDAVGKCRSAGIKVIMVTGDHPITSQG 94
>13525
          Length = 645

 Score = 42.7 bits (99), Expect = 9e-04,   Method: Composition-based stats.
 Identities = 17/33 (51%), Positives = 26/33 (78%)
 Frame = +2

Query: 437 SVKKMMKDNNLVRHLDACETMGNATAICSDKTG 469
           + K+M + N LV++L+A ET+G+ + ICSDKTG
Sbjct: 5   TAKRMARKNCLVKNLEAVETLGSTSTICSDKTG 103
>14321
          Length = 568

 Score = 39.7 bits (91), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 33/89 (37%), Positives = 44/89 (49%), Gaps = 1/89 (1%)
 Frame = +2

Query: 716 PKDDFLCLEGKEFNSLIRNEKGEVEQEKLDKIW-PKLRVLARSSPTDKHTLVKGIIDSTA 774
           PK D LCL G+    L      + +  KL ++  P  RV AR +P  K  ++     +  
Sbjct: 173 PKYD-LCLTGESLTFL------QSDHPKLLRLLLPNTRVFARVAPKQKELII-----TVL 316

Query: 775 GEQRQVVAVTGDGTNDGPALKKADVGFAM 803
             Q  V  + GDGTND  ALK ADVG A+
Sbjct: 317 KAQGFVTLMCGDGTNDVGALKHADVGVAL 403
>07486
          Length = 763

 Score = 38.5 bits (88), Expect = 0.015,   Method: Composition-based stats.
 Identities = 20/43 (46%), Positives = 27/43 (62%)
 Frame = -1

Query: 793 ALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGR 835
           AL +ADVG A+G  GTDVA EA+DI+L   +   +  A+   R
Sbjct: 742 ALAQADVGIAIG-TGTDVAVEAADIVLMKSDLVDVYAAIKLSR 617
>32708
          Length = 860

 Score = 30.0 bits (66), Expect = 6.0,   Method: Composition-based stats.
 Identities = 15/48 (31%), Positives = 26/48 (54%), Gaps = 2/48 (4%)
 Frame = +3

Query: 966  NTFV--LMQLFNEINARKIHGEKNVFAGVYRNIIFCTVVLGTFFCQIM 1011
            NTF+  L+ L +    R   G+ NVFA    + +FC++   +F  Q++
Sbjct: 132  NTFISALLNLSDTNGLRSTGGDCNVFASAPLSFLFCSLAFNSFSQQVL 275
>26294
          Length = 430

 Score = 30.0 bits (66), Expect = 6.4,   Method: Composition-based stats.
 Identities = 10/22 (45%), Positives = 13/22 (59%)
 Frame = -3

Query: 1016 GGKPFSCTSLTMEQWMWCLFIG 1037
            GG P SC S  ++ W WC  +G
Sbjct: 98   GGSPQSCQSCCLDCWAWCCPLG 33
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|54873604|ref|NP_001003815.1| erythrocyte protein band
4.1-like 1 isoform b [Mus musculus]
         (866 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

00990                                                                 402   e-112
18811                                                                 191   1e-48
11374                                                                 186   3e-47
17332                                                                 152   8e-37
13951                                                                  64   3e-19
28244                                                                  78   1e-14
05888                                                                  54   2e-07
08363                                                                  37   0.024
03469                                                                  37   0.029
19662                                                                  30   3.6  
17284                                                                  29   6.9  
>00990
          Length = 3161

 Score =  402 bits (1034), Expect = e-112,   Method: Compositional matrix adjust.
 Identities = 197/365 (53%), Positives = 254/365 (69%), Gaps = 11/365 (3%)
 Frame = +3

Query: 85  KSPQKIAKKFKSAICRVTLLDASEYECEVEKHGRGQVLFDLVCEHLNLLEKDYFGLTYCD 144
           KSPQK  +  K     V LLD      E++++  G+ LFD VC+HL+L+EKDYFGL + D
Sbjct: 225 KSPQK-QRTGKGFNYEVVLLDGEHVNFELDRNAEGRELFDKVCQHLDLIEKDYFGLQFVD 401

Query: 145 ---ADSQKNWLDPSKEIKKQIRSSPWNFAFTVKFYPPDPAQLTEDITRYYLCLQLRADII 201
              ++  K WL P K I KQ +  PW F F +KFYPPDP QL E +TR+ + LQ R DI+
Sbjct: 402 ERISNHLKCWLSPDKRISKQKKGGPWLFDFALKFYPPDPTQLRESLTRWLVVLQTRRDIL 581

Query: 202 TGRLPCSFVTHALLGSYAVQAELGDYDAEEHVG-NYVSELRFAPNQTRELEERIMELHKT 260
           +G+LP +++T A+LGSY VQA++GDYD  EH G  Y+ +  FAPNQT +L E+I+ELH+ 
Sbjct: 582 SGKLPATYLTQAMLGSYCVQADVGDYDPNEHRGVEYIRDTPFAPNQTIDLLEKIVELHRQ 761

Query: 261 YRGMTPGEAEIHFLENAKKLSMYGVDLHHAKDSEGIDIMLGVCANGLLIYRDRLRINRFA 320
           ++G TP EAE +FLENAKKL+MYGVDLH A+D   +DIMLGVCA+GL +YR++LRI+RF 
Sbjct: 762 HKGQTPDEAETNFLENAKKLAMYGVDLHAAQDVNNVDIMLGVCASGLQVYREKLRISRFV 941

Query: 321 WPKILKISYKRSNFYIKIRPGEYEQFESTIGFKLPNHRSAKRLWKVCIEHHTFFRLVSPE 380
           WPKILKISYKR  FYIK+RP +    E++  FKL  HR AKRLWK+C+EHH FFRL   E
Sbjct: 942 WPKILKISYKRRQFYIKVRPSDNSAMENSFCFKLATHRLAKRLWKICVEHHAFFRLREAE 1121

Query: 381 PPPKG--FLVMGSKFRYSGRTQAQTRQASALIDRPAPFFERSSSKRYTM-----SRSLDG 433
                  F  +GSKFRYSGRT  QTRQ+S ++DRP P+FERS   R +      + SLD 
Sbjct: 1122QSQNAAMFPRLGSKFRYSGRTLYQTRQSSQILDRPNPYFERSQPARSSFAPPAKASSLDE 1301

Query: 434 EFSRP 438
             +RP
Sbjct: 1302LSNRP 1316

 Score = 33.5 bits (75), Expect = 0.35,   Method: Compositional matrix adjust.
 Identities = 17/43 (39%), Positives = 26/43 (60%), Gaps = 2/43 (4%)
 Frame = +3

Query: 803  GFSETRIEKRIIITG--DEDVDQDQALALAIKEAKLQHPDMLV 843
            G   TR+E +++++   DE+ D D ALA AI+     +PDM V
Sbjct: 2151 GIQHTRVEHKVVLSSADDEEFDYDAALADAIRSVTEFNPDMSV 2279
>18811
          Length = 478

 Score =  191 bits (484), Expect = 1e-48,   Method: Compositional matrix adjust.
 Identities = 82/138 (59%), Positives = 111/138 (80%)
 Frame = -2

Query: 228 DAEEHVGNYVSELRFAPNQTRELEERIMELHKTYRGMTPGEAEIHFLENAKKLSMYGVDL 287
           D   H  +Y+ ++ FAPNQ  EL E+I+ELH+ ++G TP EAE+++LENAKKLSMYGVDL
Sbjct: 414 D*RHHGADYIKDIPFAPNQAPELLEKIVELHRQHKGQTPDEAEVNYLENAKKLSMYGVDL 235

Query: 288 HHAKDSEGIDIMLGVCANGLLIYRDRLRINRFAWPKILKISYKRSNFYIKIRPGEYEQFE 347
           H A+D   +DIMLGVC++GL +YRD+LRI+RF WPKI+KISYKR +FY+K+RP + +  E
Sbjct: 234 HAAQDVNNVDIMLGVCSSGLQVYRDKLRISRFVWPKIIKISYKRKHFYVKVRPADNKGLE 55

Query: 348 STIGFKLPNHRSAKRLWK 365
           +++ F+LP HR AKRLWK
Sbjct: 54  TSVSFRLPTHRLAKRLWK 1
>11374
          Length = 800

 Score =  186 bits (473), Expect = 3e-47,   Method: Compositional matrix adjust.
 Identities = 92/169 (54%), Positives = 113/169 (66%), Gaps = 8/169 (4%)
 Frame = +3

Query: 287 LHHAKDSEGIDIMLGVCANGLLIYRDRLRINRFAWPKILKISYKRSNFYIKIRPGEYEQF 346
           LH A+D   +DIMLGVCA+GL +YR++LRI+RF WPKILKISYKR  FYIK+RP +    
Sbjct: 3   LHAAQDVNNVDIMLGVCASGLQVYREKLRISRFVWPKILKISYKRRQFYIKVRPSDNSAM 182

Query: 347 ESTIGFKLPNHRSAKRLWKVCIEHHTFFRLVSPEPPPKG--FLVMGSKFRYSGRTQAQTR 404
           E++  FKL  HR AKRLWK+C+EHH FFRL   E       F  +GSKFRYSGRT  QTR
Sbjct: 183 ENSFCFKLATHRLAKRLWKICVEHHAFFRLREAEQSQNAAMFPRLGSKFRYSGRTLYQTR 362

Query: 405 QASALIDRPAPFFERSSSKRYTM------SRSLDGEFSRPASVSENHDA 447
            +S  +DRP P+FERS   R T       SRS+D   +RP    ++ DA
Sbjct: 363 HSSQTLDRPDPYFERSQPARNTYAAPSTRSRSVDELTNRPDYWKDDLDA 509
>17332
          Length = 473

 Score =  152 bits (383), Expect = 8e-37,   Method: Composition-based stats.
 Identities = 75/157 (47%), Positives = 104/157 (66%), Gaps = 2/157 (1%)
 Frame = +2

Query: 105 DASEYECEVEKHGRGQVLFDLVCEHLNLLEKDYFGLTYCDADSQKNWLDPSKEIKKQIR- 163
           D S+++ +V+ + +G +L + VCE LNL EKDYFGL + DA  Q +WLD +K +  Q++ 
Sbjct: 2   DDSDHQLQVKGNWKGILLQEKVCELLNLHEKDYFGLRFIDASGQTHWLDGNKSLSSQLKG 181

Query: 164 -SSPWNFAFTVKFYPPDPAQLTEDITRYYLCLQLRADIITGRLPCSFVTHALLGSYAVQA 222
             +P    F VKFY  DP +L E+ITRY   LQ++ DI+ GRLP +F   + L +YAVQ+
Sbjct: 182 CQTPHKLYFGVKFYAADPCKLREEITRYLFFLQVKQDILQGRLPVTFDEASELCAYAVQS 361

Query: 223 ELGDYDAEEHVGNYVSELRFAPNQTRELEERIMELHK 259
           ELGD+D  +H   YVSE  F PNQT ELE R+  LH+
Sbjct: 362 ELGDFDPRQHTDGYVSEFCFIPNQTEELERRVAGLHR 472
>13951
          Length = 720

 Score = 63.9 bits (154), Expect(2) = 3e-19,   Method: Compositional matrix adjust.
 Identities = 35/79 (44%), Positives = 47/79 (59%), Gaps = 3/79 (3%)
 Frame = -2

Query: 85  KSPQKIAKKFKSAICRVTLLDASEYECEVEKHGRGQVLFDLVCEHLNLLEKDYFGLTYCD 144
           KSPQK  +  K     V LLD      E++++  G+ LFD VC+HL+L+EKDYFGL + D
Sbjct: 425 KSPQK-QRTGKGFNYEVVLLDGEHVNFELDRNAEGRELFDKVCQHLDLIEKDYFGLQFVD 249

Query: 145 ---ADSQKNWLDPSKEIKK 160
              ++  K WL P K I K
Sbjct: 248 ERISNHLKCWLSPDKRISK 192

 Score = 50.4 bits (119), Expect(2) = 3e-19,   Method: Composition-based stats.
 Identities = 18/45 (40%), Positives = 29/45 (64%)
 Frame = -1

Query: 156 KEIKKQIRSSPWNFAFTVKFYPPDPAQLTEDITRYYLCLQLRADI 200
           K+ + + +  PW F F +KFYPPDP QL E +TR+ + L +  ++
Sbjct: 204 KDFQNRKKGGPWLFDFALKFYPPDPTQLRESLTRWLVVLHVAGEL 70
>28244
          Length = 422

 Score = 78.2 bits (191), Expect = 1e-14,   Method: Composition-based stats.
 Identities = 45/124 (36%), Positives = 67/124 (54%), Gaps = 5/124 (4%)
 Frame = -1

Query: 308 LIYRDRLRINRFAWPKILKISYKRSNF-YIKIRPGEYEQFESTIG-FKLPNHRSAKRLWK 365
           L++    +I  F WPK+ ++ +K      + +   E  Q +  I  F+L + ++ K LWK
Sbjct: 422 LVFEGNXKIGLFFWPKMTRLDFKGKKLTLVAVEDDENGQSQDHIFVFRLQSEKACKHLWK 243

Query: 366 VCIEHHTFFRLVSPEPPP---KGFLVMGSKFRYSGRTQAQTRQASALIDRPAPFFERSSS 422
             +EHH FFRL  P   P   + F  MGS+FRYSGRT+ QT   +    R +  FER  S
Sbjct: 242 CAVEHHAFFRLKGPVQGPNARQNFFRMGSRFRYSGRTEYQTSTMNRA--RRSVKFERKPS 69

Query: 423 KRYT 426
           +RY+
Sbjct: 68  QRYS 57
>05888
          Length = 490

 Score = 54.3 bits (129), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 31/65 (47%), Positives = 39/65 (60%), Gaps = 6/65 (9%)
 Frame = -2

Query: 389 MGSKFRYSGRTQAQTRQASALIDRPAPFFERSSSKRYTM------SRSLDGEFSRPASVS 442
           +GSKFRYSGRT  Q R +S  +DRP P+FERS   R T       SRS+D   +RP    
Sbjct: 489 LGSKFRYSGRTLYQARHSSQTLDRPDPYFERSQPARNTYAAPSTRSRSVDELTNRPDYWK 310

Query: 443 ENHDA 447
           ++ DA
Sbjct: 309 DDLDA 295
>08363
          Length = 1878

 Score = 37.4 bits (85), Expect = 0.024,   Method: Compositional matrix adjust.
 Identities = 19/42 (45%), Positives = 27/42 (64%), Gaps = 1/42 (2%)
 Frame = +1

Query: 803 GFSETRIEKRIIITG-DEDVDQDQALALAIKEAKLQHPDMLV 843
           G  ETR+E R++++  D+D D D ALA AI+     +PDM V
Sbjct: 337 GVQETRVEHRVVLSSTDDDFDYDAALADAIRSVTEFNPDMSV 462
>03469
          Length = 1275

 Score = 37.4 bits (85), Expect = 0.029,   Method: Compositional matrix adjust.
 Identities = 19/42 (45%), Positives = 27/42 (64%), Gaps = 1/42 (2%)
 Frame = -3

Query: 803  GFSETRIEKRIIITG-DEDVDQDQALALAIKEAKLQHPDMLV 843
            G  ETR+E R++++  D+D D D ALA AI+     +PDM V
Sbjct: 1093 GVQETRVEHRVVLSSTDDDFDYDAALADAIRSVTEFNPDMSV 968
>19662
          Length = 698

 Score = 30.4 bits (67), Expect = 3.6,   Method: Composition-based stats.
 Identities = 18/57 (31%), Positives = 24/57 (42%)
 Frame = +3

Query: 374 FRLVSPEPPPKGFLVMGSKFRYSGRTQAQTRQASALIDRPAPFFERSSSKRYTMSRS 430
           FRL S  P PKG L      + SG T  Q   A  L+    PF+  S    +   ++
Sbjct: 231 FRLRSSGPEPKGILHFSEHLQLSGETSVQYVAAMVLV----PFYPASMGSLFQXGKT 389
>17284
          Length = 489

 Score = 29.3 bits (64), Expect = 6.9,   Method: Composition-based stats.
 Identities = 11/29 (37%), Positives = 19/29 (65%)
 Frame = +3

Query: 300 LGVCANGLLIYRDRLRINRFAWPKILKIS 328
           L VC N  ++ +  L+I++  WPK+L +S
Sbjct: 75  LNVCLNSCVL*K*ILKIDKLRWPKVLTVS 161
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|134031994|ref|NP_032970.2| proteasome (prosome,
macropain) subunit, alpha type 2 [Mus musculus]
         (234 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

14551                                                                 396   e-111
28971                                                                 114   5e-52
02448                                                                 168   1e-42
24591                                                                 168   2e-42
00789                                                                 158   2e-39
20771                                                                 134   3e-32
17033                                                                 125   2e-29
04255                                                                 103   7e-23
19133                                                                  77   7e-15
37174                                                                  51   4e-07
11023                                                                  37   0.008
26690                                                                  30   1.2  
>14551
          Length = 1344

 Score =  396 bits (1018), Expect = e-111,   Method: Compositional matrix adjust.
 Identities = 188/236 (79%), Positives = 213/236 (90%), Gaps = 2/236 (0%)
 Frame = +3

Query: 1   MAERGYSFSLTTFSPSGKLVQIEYALAAVAGGAPSVGIKAANGVVLATEKKQKSILYDER 60
           M ER YSFSLTTFSPSGKLVQIEYALAAV  GAPSVGIKA NGVVLATEKKQKS+ YDE 
Sbjct: 141 MTER-YSFSLTTFSPSGKLVQIEYALAAVGAGAPSVGIKATNGVVLATEKKQKSVXYDEH 317

Query: 61  SVHKVEPITKHIGLVYSGMGPDYRVLVHRARKLAQQYYLVYQEPIPTAQLVQRVASVMQE 120
           S++KVE ITK+IG+VYSGMGPDYRVL  RARKLA+QY  VY E IPTAQLVQRVA+VMQE
Sbjct: 318 SINKVETITKNIGIVYSGMGPDYRVLCRRARKLAEQYKRVYNEQIPTAQLVQRVAAVMQE 497

Query: 121 YTQSGGVRPFGVSLLICGWNEG--RPYLFQSDPSGAYFAWKATAMGKNYVNGKTFLEKRY 178
           +TQSGGVRPFGVSLL+ GW+E   +P+L+Q DPSGAYFAWKATAMGKN++NGKTFLEKRY
Sbjct: 498 FTQSGGVRPFGVSLLMAGWDEDDKKPFLYQCDPSGAYFAWKATAMGKNHINGKTFLEKRY 677

Query: 179 NEDLELEDAIHTAILTLKESFEGQMTEDNIEVGICNEAGFRRLTPTEVRDYLAAIA 234
           +E LELEDA+HTAIL LKESFEGQMTEDNIE+GICN +GFRRL P+E++DYLA+++
Sbjct: 678 SETLELEDAVHTAILALKESFEGQMTEDNIEIGICNSSGFRRLEPSEIKDYLASVS 845
>28971
          Length = 437

 Score =  114 bits (285), Expect(2) = 5e-52,   Method: Compositional matrix adjust.
 Identities = 52/59 (88%), Positives = 54/59 (91%)
 Frame = +1

Query: 118 MQEYTQSGGVRPFGVSLLICGWNEGRPYLFQSDPSGAYFAWKATAMGKNYVNGKTFLEK 176
           MQEYTQSGGVRPFGVSLLICGW+  RPYL+QSDPSGAYFAWKATAMGKN VNGK FL K
Sbjct: 1   MQEYTQSGGVRPFGVSLLICGWDNERPYLYQSDPSGAYFAWKATAMGKNAVNGKNFLGK 177

 Score =  107 bits (267), Expect(2) = 5e-52,   Method: Compositional matrix adjust.
 Identities = 48/64 (75%), Positives = 56/64 (87%)
 Frame = +2

Query: 170 GKTFLEKRYNEDLELEDAIHTAILTLKESFEGQMTEDNIEVGICNEAGFRRLTPTEVRDY 229
            KTFLEKRY+EDLELEDA+HTAILTLKE FEG+MT DNIEVGIC++ GF+RL P  ++DY
Sbjct: 158 AKTFLEKRYSEDLELEDAVHTAILTLKEGFEGKMTSDNIEVGICDQNGFKRLDPATIKDY 337

Query: 230 LAAI 233
           LA I
Sbjct: 338 LANI 349
>02448
          Length = 1302

 Score =  168 bits (426), Expect = 1e-42,   Method: Compositional matrix adjust.
 Identities = 89/233 (38%), Positives = 138/233 (59%), Gaps = 3/233 (1%)
 Frame = +2

Query: 1   MAERGYSFSLTTFSPSGKLVQIEYALAAVAGGAPSVGIKAANGVVLATEKKQKSILYDER 60
           M++R Y  ++T FSP G L Q+EYA  AV  G+ +VG++  N VVL  EKK  + L +ER
Sbjct: 251 MSDR-YDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGNNLVVLGVEKKAVAKLQEER 427

Query: 61  SVHKVEPITKHIGLVYSGMGPDYRVLVHRARKLAQQYYLVYQEPIPTAQLVQRVASVMQE 120
           +V K+  + +H+ L ++G+  D R+L++RAR   Q + L  ++P+    + + +A + Q+
Sbjct: 428 TVRKIALLDEHVALAFAGLTADARILINRARIECQSHKLTVEDPVTVEYITRHIAQLKQK 607

Query: 121 YTQSGGVRPFGVSLLICGWN-EGRPYLFQSDPSGAYFAWKATAMGKNYVNGKTFLEKRYN 179
           YTQS G RPFG+S LI G++ +G P+L+Q+DPSG Y  WKA  +G+N    + FLEK Y 
Sbjct: 608 YTQSNGRRPFGLSSLIIGFDYDGSPHLYQTDPSGTYHEWKANTIGRNAKTVREFLEKHYT 787

Query: 180 EDLELEDAIHTAILTLKESFE-GQMTEDNIEVGICNEA-GFRRLTPTEVRDYL 230
           +++   D   T  L LK   E  Q    N+EV +       + L   E+  Y+
Sbjct: 788 DEVAASDK-ETIKLALKALLEVVQSGAKNMEVAVMRRGQALQMLESDEIEKYI 943
>24591
          Length = 1801

 Score =  168 bits (425), Expect = 2e-42,   Method: Compositional matrix adjust.
 Identities = 89/233 (38%), Positives = 138/233 (59%), Gaps = 3/233 (1%)
 Frame = +1

Query: 1   MAERGYSFSLTTFSPSGKLVQIEYALAAVAGGAPSVGIKAANGVVLATEKKQKSILYDER 60
           M++R Y  ++T FSP G L Q+EYA  AV  G+ +VG++  N VVL  EKK  + L +ER
Sbjct: 28  MSDR-YDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGDNLVVLGVEKKAVAKLQEER 204

Query: 61  SVHKVEPITKHIGLVYSGMGPDYRVLVHRARKLAQQYYLVYQEPIPTAQLVQRVASVMQE 120
           +V K+  + +H+ L ++G+  D R+L++RAR   Q + L  ++P+    + + +A + Q+
Sbjct: 205 TVRKIALLDEHVALAFAGLTADARILINRARIECQSHKLTVEDPVTVEYITRHIAQLKQK 384

Query: 121 YTQSGGVRPFGVSLLICGWN-EGRPYLFQSDPSGAYFAWKATAMGKNYVNGKTFLEKRYN 179
           YTQS G RPFG+S LI G++ +G P+L+Q+DPSG Y  WKA  +G+N    + FLEK Y 
Sbjct: 385 YTQSNGRRPFGLSSLIIGFDYDGTPHLYQTDPSGTYHEWKANTIGRNAKTVREFLEKHYT 564

Query: 180 EDLELEDAIHTAILTLKESFE-GQMTEDNIEVGICNEA-GFRRLTPTEVRDYL 230
           +++   D   T  L LK   E  Q    N+EV +       + L   E+  Y+
Sbjct: 565 DEVAASDK-ETIKLALKALLEVVQSGAKNMEVAVMRRGQALQMLESDEIEKYI 720
>00789
          Length = 1584

 Score =  158 bits (399), Expect = 2e-39,   Method: Compositional matrix adjust.
 Identities = 84/212 (39%), Positives = 126/212 (59%), Gaps = 4/212 (1%)
 Frame = +1

Query: 4   RGYSFSLTTFSPSGKLVQIEYALAAVAGGAPSVGIKAANGVVLATEKKQKSILYDERS-V 62
           R Y    T FSP G+L Q+EYA+ A+      +GI A +G+VLA E++  + L DE S  
Sbjct: 28  RRYDSRTTIFSPEGRLYQVEYAMEAIGHAGTCLGILAKDGIVLAAERRNTNKLLDEVSYS 207

Query: 63  HKVEPITKHIGLVYSGMGPDYRVLVHRARKLAQQYYLVYQEPIPTAQLVQRVASVMQEYT 122
            K+  ++  +    +G+  D  VL +  R +AQ+Y L YQEPIP  Q+V  +  + Q YT
Sbjct: 208 EKIYRLSDDMACSVAGITSDANVLTNELRLIAQRYLLQYQEPIPCEQVVATLCDIKQAYT 387

Query: 123 QSGGVRPFGVSLLICGWNEGRPY-LFQSDPSGAYFAWKATAMGKNYVNGKTFLEKRYNED 181
           Q GG RPFGVS+L  GW++   + L+QSDPSG Y  WKAT +G N  N  + L++ Y ED
Sbjct: 388 QFGGKRPFGVSILYMGWDKHYGFQLYQSDPSGNYGGWKATCIGNNSANAVSLLKQEYKED 567

Query: 182 -LELEDAIHTAILTLKESFE-GQMTEDNIEVG 211
              L++A+  +I  L ++ +  ++T D +E+ 
Sbjct: 568 ESSLDEALALSIKVLGKTLDLTKLTPDKVEMA 663
>20771
          Length = 674

 Score =  134 bits (337), Expect = 3e-32,   Method: Compositional matrix adjust.
 Identities = 70/191 (36%), Positives = 109/191 (57%), Gaps = 5/191 (2%)
 Frame = +2

Query: 6   YSFSLTTFSPSGKLVQIEYALAAVAGGAPSVGIKAANGVVLATEKKQKSILYDERSVHKV 65
           Y   + TFSP G+L Q+EYA+ A+  G+ ++GI+   GVVLA EK+  S L +  S+ K+
Sbjct: 101 YDRGVNTFSPEGRLFQVEYAIEAIKLGSTAIGIQTNEGVVLAVEKRVTSSLIEPTSIEKI 280

Query: 66  EPITKHIGLVYSGMGPDYRVLVHRARKLAQQYYLVYQEPIPTAQLVQRVASVMQEYTQS- 124
             + KHIG   SG+  D R L+ RAR  AQ ++  Y E +    + Q V+++   +    
Sbjct: 281 MEVDKHIGCAMSGLIADSRTLIDRARVEAQNHWFTYNENMSVESVTQAVSNLALAFGDDD 460

Query: 125 ---GGV-RPFGVSLLICGWNEGRPYLFQSDPSGAYFAWKATAMGKNYVNGKTFLEKRYNE 180
              G + RPFGV+LLI G +   P LF  DPSG +  + A A+G      +  L+++Y++
Sbjct: 461 PDPGAMSRPFGVALLIAGVDSNGPRLFHMDPSGTFIQYDAKAIGSGSEGAQQALQEQYHK 640

Query: 181 DLELEDAIHTA 191
            + L+DA  +A
Sbjct: 641 SITLKDACKSA 673
>17033
          Length = 2217

 Score =  125 bits (314), Expect = 2e-29,   Method: Compositional matrix adjust.
 Identities = 64/184 (34%), Positives = 102/184 (55%)
 Frame = -3

Query: 5    GYSFSLTTFSPSGKLVQIEYALAAVAGGAPSVGIKAANGVVLATEKKQKSILYDERSVHK 64
            GY  S + FSP G++ Q+EYA  AV     ++GI+  +GVV+  EK   S LY++ +  +
Sbjct: 2152 GYDLSASHFSPDGRVFQVEYAQKAVENSGTAIGIRGKDGVVMGVEKLVTSKLYEQGANKR 1973

Query: 65   VEPITKHIGLVYSGMGPDYRVLVHRARKLAQQYYLVYQEPIPTAQLVQRVASVMQEYTQS 124
            +  I +HIG   +G+  D R L+ RA++ +  Y   Y  P+P   L  RVA  +  YT  
Sbjct: 1972 LFNIDRHIGGAVAGLLADARQLMERAKEESSNYRFNYGSPVPLKYLTDRVAGYVHAYTLH 1793

Query: 125  GGVRPFGVSLLICGWNEGRPYLFQSDPSGAYFAWKATAMGKNYVNGKTFLEKRYNEDLEL 184
              VRPFG S+++  ++   P +F  +PSG  + +   A+GK     KT +EK   +DL +
Sbjct: 1792 SAVRPFGTSMIVASYDAVGPQMFLVEPSGVSWGYYGCAIGKAKQTAKTEIEKLKMKDLTM 1613

Query: 185  EDAI 188
            +D +
Sbjct: 1612 QDLV 1601
>04255
          Length = 1758

 Score =  103 bits (256), Expect = 7e-23,   Method: Compositional matrix adjust.
 Identities = 72/240 (30%), Positives = 112/240 (46%), Gaps = 9/240 (3%)
 Frame = -2

Query: 4    RGYSFSLTTFSPSGKLVQIEYALAAVAGGAPS----VGIKAANGVVLATEKKQKSILYDE 59
            RG S  LT    S    QI  +   + G  P      G +          +K    L D 
Sbjct: 1622 RGSSAGLTVSLQSFS*RQIVSSRVCLQGYQPGRTDFCGCQRKRQRCYCHTEKVPDKLLDP 1443

Query: 60   RSVHKVEPITKHIGLVYSGMGPDYRVLVHRARKLAQQYYLVYQEPIPTAQLVQRVASVMQ 119
             +V  +  +T+ IG V +GM  D +  V RAR  A ++   Y   IP   L +R+A++ Q
Sbjct: 1442 TTVTHLYSLTERIGCVMTGMIADSQSQVQRARYEAAKWKYTYGYDIPVDMLCKRIANINQ 1263

Query: 120  EYTQSGGVRPFGVSLLICGWNEGR-PYLFQSDPSGAYFAWKATAMGKNYVNGKTFLEKRY 178
             YTQS  +RP G  +++ G+++ + P ++++DP+G Y  +KAT+ G   +    FLEK+ 
Sbjct: 1262 VYTQSAEMRPLGCCMILIGYDDEKGPEVYKTDPAGYYCGFKATSAGSKQLEANGFLEKKI 1083

Query: 179  --NEDLELEDAIHTAILTLKESFEGQMTEDNIEVGIC--NEAGFRRLTPTEVRDYLAAIA 234
               +D    +A   AI  L            +EVGI   +   FR LT  ++  +L AIA
Sbjct: 1082 KKKQDFTYNEAAEIAITCLSTVLSADFKASEVEVGIVTKDNPNFRILTEADIDVHLTAIA 903
>19133
          Length = 692

 Score = 76.6 bits (187), Expect = 7e-15,   Method: Compositional matrix adjust.
 Identities = 45/157 (28%), Positives = 82/157 (52%), Gaps = 5/157 (3%)
 Frame = +1

Query: 82  DYRVLVHRARKLAQQYYLVYQEPIPTAQLVQRVASVMQEYTQSGGVRPFGVSLLICGWNE 141
           D R+L +  +         YQ+P+P ++LV  + + +Q  T   G RPFGV LLI G++ 
Sbjct: 10  DARLLCNFMQTECLDSRWAYQQPLPVSRLVSAIGNKLQIPTHRYGRRPFGVGLLIAGYDW 189

Query: 142 GRPYLFQSDPSGAYFAWKATAMGKNYVNGKTFLEKRYNE--DLELEDAIHTAILTLKESF 199
             P+++Q+ PS  Y+  KA A+G    + +T+LE+  ++     L++ +   +  L+++ 
Sbjct: 190 SGPHIYQTCPSANYYDCKAMAIGARSQSARTYLERHLDQFPQCSLDELVKHGLRALRDTL 369

Query: 200 EGQMT--EDNIEVGICN-EAGFRRLTPTEVRDYLAAI 233
             ++T    N  +GI + +  F+      V  YLA I
Sbjct: 370 PSEVTLSTKNCSLGIVDKDMKFKIYDDENVASYLALI 480
>37174
          Length = 146

 Score = 50.8 bits (120), Expect = 4e-07,   Method: Compositional matrix adjust.
 Identities = 25/32 (78%), Positives = 27/32 (84%)
 Frame = +1

Query: 15 PSGKLVQIEYALAAVAGGAPSVGIKAANGVVL 46
          P+ +LVQIEYALAAV  GAP VGIKA NGVVL
Sbjct: 43 PTAQLVQIEYALAAVGAGAPVVGIKATNGVVL 138

 Score = 33.1 bits (74), Expect = 0.089,   Method: Compositional matrix adjust.
 Identities = 16/21 (76%), Positives = 17/21 (80%)
 Frame = +1

Query: 92  KLAQQYYLVYQEPIPTAQLVQ 112
           KLA+QY  VY E IPTAQLVQ
Sbjct: 1   KLAEQYKRVYNEQIPTAQLVQ 63
>11023
          Length = 1057

 Score = 36.6 bits (83), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 15/45 (33%), Positives = 30/45 (66%), Gaps = 1/45 (2%)
 Frame = -2

Query: 134 LLICGWNEGR-PYLFQSDPSGAYFAWKATAMGKNYVNGKTFLEKR 177
           +++ G+++ + P ++++DP+G Y  +KAT+ G   +    FLEKR
Sbjct: 996 MILIGYDDEKGPEVYKTDPAGYYCGFKATSAGSKQLEANGFLEKR 862
>26690
          Length = 450

 Score = 29.6 bits (65), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 20/57 (35%), Positives = 29/57 (50%), Gaps = 1/57 (1%)
 Frame = +2

Query: 159 KATAMGKNYVNGKT-FLEKRYNEDLELEDAIHTAILTLKESFEGQMTEDNIEVGICN 214
           K  +  K+ V GK+  LE+     LEL      AI    +++ G+MT  +I  GICN
Sbjct: 65  KVRSCYKDVVKGKSDLLEQDRRTMLELGVVTQPAITINNQTYRGEMTGFDIFKGICN 235
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|22550094|ref|NP_032950.1| protein kinase, cAMP
dependent regulatory, type II alpha [Mus musculus]
         (402 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

08195                                                                 398   e-111
27710                                                                 132   2e-31
18204                                                                  91   7e-19
20517                                                                  46   2e-05
27853                                                                  34   0.095
27148                                                                  29   2.7  
>08195
          Length = 2165

 Score =  398 bits (1023), Expect = e-111,   Method: Compositional matrix adjust.
 Identities = 199/396 (50%), Positives = 259/396 (65%), Gaps = 2/396 (0%)
 Frame = -3

Query: 6    IPAGLTELLQGYTVEVLRQQPPDLVDFAVEYFTRLREARRQESDTFIVSPTTFHTQESSA 65
            IP GLTELLQ +TV  LR++P DLVDFA  YF RLR       D    +     +Q  S 
Sbjct: 2019 IPPGLTELLQEFTVAALRERPSDLVDFAASYFNRLRLLNGDAVDPKCFTGGVRFSQTGSH 1840

Query: 66   VPVIXXXXXXXXXXXXXXXXVPVPSKFTR--RVSVCAETFXXXXXXXXXXXRVVHPKTDE 123
            +                    P PS   R  R SV AE +           ++V+PK+D 
Sbjct: 1839 ILAHNGTFAQNNSDDDEAMLEPPPSNTARFRRKSVSAEAYNPETDEDGGEAKIVNPKSDI 1660

Query: 124  QRCRLQEACKDILLFKNLDQEQLSQVLDAMFEKIVKTDEHVIDQGDDGDNFYVIERGTYD 183
            QR RL +  K+ILLF++LD EQ+ +VLDAMFEK V+  EH+IDQGDDGDNFYVI+ GTYD
Sbjct: 1659 QRQRLADVVKNILLFRSLDPEQMQEVLDAMFEKSVQPGEHIIDQGDDGDNFYVIDSGTYD 1480

Query: 184  ILVTKDNQTRSVGQYDNRGSFGELALMYNTPRAATIIATSEGSLWGLDRVTFRRIIVKNN 243
            I V  + Q + VG YDN G FGELALMYN PRAATIIA+S G++W LDR TFRRI++K  
Sbjct: 1479 IYVDVEGQAKLVGNYDNSGFFGELALMYNMPRAATIIASSTGTIWALDRTTFRRIVLKTA 1300

Query: 244  AKKRKMFESFIESVPLFKSLEMSERMKIVDVIGEKIYKDGERIIAQGEKADSFYIIESGE 303
             +KRK +ES +ESVPL KSL++ ERM + D +  + Y+DG +II QG+ AD  Y +ESG+
Sbjct: 1299 FQKRKKYESLLESVPLLKSLDLYERMNVADALQTRTYEDGVQIIKQGDAADVMYFVESGQ 1120

Query: 304  VSILIRSKTKSNKNGGNQEVEIAHCHKGQYFGELALVTNKPRAASAYAVGDVKCLVMDVQ 363
            V I + +K  ++ + G  E ++    KG YFGELAL+T++PRAASAYA G VKC V+DV 
Sbjct: 1119 VRIAMTNKESTDPSAG--ETDVTVLEKGGYFGELALITHQPRAASAYAQGTVKCAVLDVH 946

Query: 364  AFERLLGPCMDIMKRNISHYEEQLVKMFGSNLDLMD 399
            AFERL+GPCMD++KRNI  Y+ Q+  +FG ++ + D
Sbjct: 945  AFERLMGPCMDVLKRNIDDYDSQISSIFGKSVSMKD 838
>27710
          Length = 429

 Score =  132 bits (332), Expect = 2e-31,   Method: Compositional matrix adjust.
 Identities = 66/146 (45%), Positives = 93/146 (63%)
 Frame = +2

Query: 162 EHVIDQGDDGDNFYVIERGTYDILVTKDNQTRSVGQYDNRGSFGELALMYNTPRAATIIA 221
           E++I QGD+GDNFYVI+ G  D+ V     +  V      GSFGELAL+Y TPRAAT+ A
Sbjct: 2   ENIIQQGDEGDNFYVIDVGEVDVFV----NSELVTTISEGGSFGELALIYGTPRAATVRA 169

Query: 222 TSEGSLWGLDRVTFRRIIVKNNAKKRKMFESFIESVPLFKSLEMSERMKIVDVIGEKIYK 281
            S+  LWG+DR ++RRI++ +  +KRKM+E F+  V + +SL+  ER+ + D +    + 
Sbjct: 170 KSDVKLWGIDRDSYRRILMGSTIRKRKMYEEFLSRVSILESLDKWERLTVADSLETCAFD 349

Query: 282 DGERIIAQGEKADSFYIIESGEVSIL 307
           DGE I+ QG   D FYII  G   +L
Sbjct: 350 DGETIVKQGAAGDDFYIILEGCAVVL 427

 Score = 60.5 bits (145), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 37/107 (34%), Positives = 55/107 (51%)
 Frame = +2

Query: 284 ERIIAQGEKADSFYIIESGEVSILIRSKTKSNKNGGNQEVEIAHCHKGQYFGELALVTNK 343
           E II QG++ D+FY+I+ GEV + + S+             +    +G  FGELAL+   
Sbjct: 2   ENIIQQGDEGDNFYVIDVGEVDVFVNSEL------------VTTISEGGSFGELALIYGT 145

Query: 344 PRAASAYAVGDVKCLVMDVQAFERLLGPCMDIMKRNISHYEEQLVKM 390
           PRAA+  A  DVK   +D  ++ R+L   M    R    YEE L ++
Sbjct: 146 PRAATVRAKSDVKLWGIDRDSYRRIL---MGSTIRKRKMYEEFLSRV 277

 Score = 31.2 bits (69), Expect = 0.75,   Method: Compositional matrix adjust.
 Identities = 18/71 (25%), Positives = 35/71 (49%)
 Frame = +2

Query: 115 RVVHPKTDEQRCRLQEACKDILLFKNLDQEQLSQVLDAMFEKIVKTDEHVIDQGDDGDNF 174
           R++   T  +R   +E    + + ++LD+ +   V D++        E ++ QG  GD+F
Sbjct: 215 RILMGSTIRKRKMYEEFLSRVSILESLDKWERLTVADSLETCAFDDGETIVKQGAAGDDF 394

Query: 175 YVIERGTYDIL 185
           Y+I  G   +L
Sbjct: 395 YIILEGCAVVL 427
>18204
          Length = 429

 Score = 91.3 bits (225), Expect = 7e-19,   Method: Compositional matrix adjust.
 Identities = 52/150 (34%), Positives = 84/150 (56%), Gaps = 1/150 (0%)
 Frame = -1

Query: 203 SFGELALMYNTPRAATIIATSEGSLWGLDRVTFRRIIVKNNAKKRKMFESFIESVPLFKS 262
           +FGELA++YN  R A++ A ++  +W LDR  F+ I++K   ++R+    F++SV + + 
Sbjct: 429 AFGELAILYNCTRTASVKAVTDVKVWVLDRQMFQAIMMKTGLQRREENIRFLKSVSVLRD 250

Query: 263 LEMSERMKIVDVIGEKIYKDGERIIAQGEKADSFYIIESGEVSILIRSKTKSNKNGGNQE 322
           L   +  KI DV+    + +GE II +G   D+F++I  GEV +       +    G++E
Sbjct: 249 LPSDKLAKIADVLEIDFFHEGEFIIREGCTGDTFFLINKGEVRV-------TQTVAGHEE 91

Query: 323 -VEIAHCHKGQYFGELALVTNKPRAASAYA 351
             EI    +G YFGE AL+    R AS  A
Sbjct: 90  PQEIRKLKRGDYFGEKALLGEDRRTASCIA 1

 Score = 38.9 bits (89), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 22/54 (40%), Positives = 30/54 (55%)
 Frame = -1

Query: 334 FGELALVTNKPRAASAYAVGDVKCLVMDVQAFERLLGPCMDIMKRNISHYEEQL 387
           FGELA++ N  R AS  AV DVK  V+D Q F+ ++      MK  +   EE +
Sbjct: 426 FGELAILYNCTRTASVKAVTDVKVWVLDRQMFQAIM------MKTGLQRREENI 283
>20517
          Length = 749

 Score = 46.2 bits (108), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 42/175 (24%), Positives = 80/175 (45%), Gaps = 11/175 (6%)
 Frame = +3

Query: 169 DDGDNFYVIERGTYDILVTK----DNQTRSVGQYDNRGSFGELALMYNTPRAATIIATSE 224
           D   +FY I  GT  ++VT+     + TR++   D   SFGELA++  + R AT+   +E
Sbjct: 6   DPPRSFYFILSGT--VVVTQFERQYSTTRTLVTLDQGMSFGELAVITGSRRQATVSTMTE 179

Query: 225 GSLWGLDRVTFRRIIVKNNAKKRKMF-----ESFIESVPLFKSLEMSERMKIVDVIGEKI 279
             L  +    F  I +   A  RK+        F+ SV   K+  + +  +         
Sbjct: 180 VELLCISAKDFEDIFM---AGGRKIITDPDHNKFLRSVDFLKAWPVQQLAQHPHACMFHY 350

Query: 280 YKDGERIIAQGEKADSFYIIESGEVSIL--IRSKTKSNKNGGNQEVEIAHCHKGQ 332
           +  G+ ++     +D  YI++SG +S++  +   T ++++    + E+A   K +
Sbjct: 351 FNRGQVLVRDSNNSDWIYIVKSGSLSVMKKLHHATATDRHSTEGKSEVAEASKSK 515
>27853
          Length = 864

 Score = 34.3 bits (77), Expect = 0.095,   Method: Compositional matrix adjust.
 Identities = 20/80 (25%), Positives = 42/80 (52%)
 Frame = +2

Query: 278 KIYKDGERIIAQGEKADSFYIIESGEVSILIRSKTKSNKNGGNQEVEIAHCHKGQYFGEL 337
           ++ + G+ +  QG+ +DS YI+ +G      R ++     GG +EV +    +G+  G +
Sbjct: 227 QMTEAGKALFRQGDNSDSVYIVLTG------RLRSVITLLGGKKEV-VGEYGRGELVGIV 385

Query: 338 ALVTNKPRAASAYAVGDVKC 357
            ++T+  RA +  A+ D + 
Sbjct: 386 EVLTHTERATTNMAIRDTEV 445
>27148
          Length = 718

 Score = 29.3 bits (64), Expect = 2.7,   Method: Compositional matrix adjust.
 Identities = 15/25 (60%), Positives = 19/25 (76%), Gaps = 1/25 (4%)
 Frame = -3

Query: 198 YDNRG-SFGELALMYNTPRAATIIA 221
           Y NRG SFGELA+M  T R +T+I+
Sbjct: 293 YYNRGDSFGELAIMNATRRQSTVIS 219
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|56699478|ref|NP_796210.2| plasma membrane calcium
ATPase 3 [Mus musculus]
         (1220 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

12151                                                                 270   e-111
06342                                                                 258   1e-68
29829                                                                 219   5e-57
00499                                                                 207   3e-53
35407                                                                 130   3e-30
21541                                                                 127   2e-29
36566                                                                 127   3e-29
08160                                                                  64   3e-10
14773                                                                  58   2e-08
04985                                                                  54   4e-07
28890                                                                  50   5e-06
13525                                                                  43   8e-04
33697                                                                  40   0.004
07486                                                                  39   0.018
14321                                                                  37   0.056
>12151
          Length = 880

 Score =  270 bits (691), Expect(2) = e-111,   Method: Compositional matrix adjust.
 Identities = 145/198 (73%), Positives = 163/198 (82%), Gaps = 4/198 (2%)
 Frame = +3

Query: 803 KKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNVV 862
           +KADVGFAMGI+GTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSI+KFLQFQLTVNVV
Sbjct: 288 QKADVGFAMGISGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSIAKFLQFQLTVNVV 467

Query: 863 AVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLLLRKPYGRDKPLIS 922
           AV VAF GAC   DSPLKA+QMLWVNLIMDT ASLALATE P+  LL R+PYGR KPLIS
Sbjct: 468 AVFVAFVGACSIGDSPLKAIQMLWVNLIMDTLASLALATELPSSELLKRRPYGRTKPLIS 647

Query: 923 RTMMKNILGHAVYQLTIIFTLLFVG-ELFFDID---SGRNAPLHSPPSEHYTIIFNTFVM 978
           +TM KNILGHA YQ+ +I  LLF G +  +D     + R  P   P ++H+TIIFN FVM
Sbjct: 648 KTMWKNILGHAFYQILVILLLLFQGAKAVWDRRWHPTSRETP--RPTNQHFTIIFNAFVM 821

Query: 979 MQLFNEINARKIHGERNV 996
           M LFNE+NARKIH +RN+
Sbjct: 822 MTLFNEVNARKIHDQRNI 875

 Score =  152 bits (384), Expect(2) = e-111,   Method: Compositional matrix adjust.
 Identities = 72/98 (73%), Positives = 84/98 (85%)
 Frame = +1

Query: 707 DNINTARAIAAKCGIIQPGEDFLCLEGKEFNRRIRNEKGEIEQERLDKVWPKLRVLARSS 766
           DN+NTAR+IA+KCGIIQPG+D L LEGKEFN+ IR+ +GEI QE++D+VWP LRVLARSS
Sbjct: 1   DNVNTARSIASKCGIIQPGDDGLVLEGKEFNQLIRDAEGEISQEKVDEVWPNLRVLARSS 180

Query: 767 PTDKHTLVKGIIDSTTGEQRQVVAVTGDGTNDGPALKK 804
           P DK+ LVK IIDS     R+VVAVTGDGTNDGPALKK
Sbjct: 181 PQDKYILVKHIIDSKVSTSREVVAVTGDGTNDGPALKK 294
>06342
          Length = 2428

 Score =  258 bits (659), Expect = 1e-68,   Method: Compositional matrix adjust.
 Identities = 232/796 (29%), Positives = 362/796 (45%), Gaps = 74/796 (9%)
 Frame = +2

Query: 214 GDIAQVKYGDLLPADGVL--IQGNDLKIDESSLTGESDHVRKSADKDP-----------M 260
           GDI +V  GD +PAD  +  I    L+ID++ LTGES  V K  D  P           +
Sbjct: 14  GDIVEVSVGDKVPADIRILKIHSTTLRIDQAILTGESVSVMKHTDPIPDPRAVNQDKKNL 193

Query: 261 LLSGTHVMEGSGRMVVTAVGVNSQTGIIFTLLXXXXXXXXXXXXXXXXXXXXMDSSQTRA 320
           L SGT+V  G  + +V   G+ ++ G I   +                    MD+ Q + 
Sbjct: 194 LFSGTNVAAGKCKGLVIGTGLTTEIGKIRNEM--------------------MDTEQEK- 310

Query: 321 KKQDGAVAMEMQPLKSAXXXXXXXXXXXXXXXXXXXXSVLQGKLTKLAVQIGKAGLVMSA 380
                                                + LQ KL + + Q+ K       
Sbjct: 311 -------------------------------------TPLQQKLDEFSNQLSKV------ 361

Query: 381 ITVIILVLYFVIETFVVD---GRVWLAECTPVYVQYFVKFFIIGVTVLVVAVPEGLPLAV 437
           IT+I + ++ +      D   G  W        ++  + +F I V + V A+PEGLP  +
Sbjct: 362 ITIICIAVWAINIGHFNDPAHGGSW--------IKGAIYYFKIAVALAVAAIPEGLPAVI 517

Query: 438 TISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTTNRMTVVQSYL------- 490
           T  LA   ++M K N +VR L + ET+G  + ICSDKTGTLTTN+M+V + ++       
Sbjct: 518 TTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCKLFIFSQIDTN 697

Query: 491 -----------------GDTHYKEIPAPSALTPKILDLLV-------HAISINSAYTTKI 526
                            G+ +       ++  P + +L          ++  N A T   
Sbjct: 698 QIKTTQFEVTGSTYAPDGELYQNGKKVKASDYPGLEELCTICGMCNDSSVDYNEAKTQY- 874

Query: 527 LPPEKEGALPRQVGNKTECALLGFVLDL-----------KRDFQPVREQIPEDQLYKVYT 575
                      +VG  TE AL      L           KR+   V   + +D   K +T
Sbjct: 875 ----------EKVGEATETALTVLAEKLNFYNTDKSSLNKREMGTVCNHVIQDMWRKEFT 1024

Query: 576 --FNSVRKSMSTV------IRMPDGGFRLFSKGASEILLKKCTNILNSNGELRGFRPRDR 627
             F+  RKSMS         R+P GG R+F+KGA E LL +CT++   N ++    P  +
Sbjct: 1025LEFSRDRKSMSVFCVPNKPTRVP-GGARMFAKGAPEGLLDRCTHVRIGNNKVP-MSPAIK 1198

Query: 628 DDMVKKI-IEPMACDGLRTICIAYRDFSAIQEPDWDNEN-----EVVGDLTCIAVVGIED 681
           ++++K   I     D LR + +A  D    +E D D E+     E   ++T + VVG+ D
Sbjct: 1199NEIMKLTKIYGTGRDTLRCLALATIDNPPRRE-DMDLEDSRKFIEYETNMTFVGVVGMLD 1375

Query: 682 PVRPEVPEAIRKCQRAGITVRMVTGDNINTARAIAAKCGIIQPGEDF--LCLEGKEFNRR 739
           P R EV  +I+ C+ AGI V ++TGDN  TA AI  + G+    E+   L   G+EF+  
Sbjct: 1376PPREEVMASIKNCRAAGIRVIVITGDNKATAEAICRRIGVFSESENTEGLAYTGREFD-- 1549

Query: 740 IRNEKGEIEQERLDKVWPKLRVLARSSPTDKHTLVKGIIDSTTGEQRQVVAVTGDGTNDG 799
                 E+  E       + R+ AR  P  K  +V+ +       + ++ A+TGDG ND 
Sbjct: 1550------ELPPEDQRAAVMRARLFARVEPAHKSKIVEYL-----QAEGEISAMTGDGVNDA 1696

Query: 800 PALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTV 859
           PALKKA++G AMG +GT VAK AS+++L DDNF++IV AV  GR +Y+++ +F+++ ++ 
Sbjct: 1697PALKKAEIGIAMG-SGTAVAKSASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISS 1873

Query: 860 NVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLLLRKPYGRDKP 919
           N+  V+  F  A +     L  VQ+LWVNL+ D F + AL   PP   ++ + P    + 
Sbjct: 1874NIGEVVCIFLTAALGIPEALIPVQLLWVNLVTDGFPATALGFNPPDLDIMQKPPRNPREG 2053

Query: 920 LISRTMMKNILGHAVY 935
           LI+  +    +   +Y
Sbjct: 2054LITGWLFFRYMAIGIY 2101
>29829
          Length = 465

 Score =  219 bits (559), Expect = 5e-57,   Method: Compositional matrix adjust.
 Identities = 117/150 (78%), Positives = 127/150 (84%)
 Frame = -3

Query: 807 VGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIV 866
           +GFAMGI+GTDVAKEASDIILTDDNFTSIVKAV WGRNVYDSI+KFLQFQLTVNVVAV V
Sbjct: 460 LGFAMGISGTDVAKEASDIILTDDNFTSIVKAVXWGRNVYDSIAKFLQFQLTVNVVAVFV 281

Query: 867 AFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLLLRKPYGRDKPLISRTMM 926
           AF GAC   DSPL+A+QMLWVNLIMDT ASLALATE P+  LL RKPYGR KPLIS+TM 
Sbjct: 280 AFVGACSIGDSPLEAIQMLWVNLIMDTLASLALATELPSNELLKRKPYGRTKPLISKTMF 101

Query: 927 KNILGHAVYQLTIIFTLLFVGELFFDIDSG 956
           KNI GH+VYQ+ II  +LF G   F ID G
Sbjct: 100 KNIAGHSVYQIIIILVILFKGADLFGIDDG 11
>00499
          Length = 4026

 Score =  207 bits (526), Expect = 3e-53,   Method: Compositional matrix adjust.
 Identities = 184/552 (33%), Positives = 276/552 (50%), Gaps = 43/552 (7%)
 Frame = +2

Query: 432 GLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTTNRMTVVQSYL- 490
           GL   VT+ L  + K+M + N LV++L+A ET+G+ + ICSDKTGTLT NRMTV   +  
Sbjct: 2   GLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFD 181

Query: 491 -----GDTHYKEIPAPSALT-PKILDLLVHAISINSAYTTKILPPEKEGALPRQV-GNKT 543
                 DT   +  A  + + P  + L   A+  N A        +    L R+  G+ +
Sbjct: 182 GRIVEADTSDDQSNATYSRSDPTWMALSRVAMLCNRAEFKG--NQDNVPILKRECNGDAS 355

Query: 544 ECALL-------GFVLDLKRDFQPVREQIPEDQLYKVYTFNSVRKSMSTVIRMPDGG--- 593
           E ALL       G V + +R  + + E IP         FNS  K   ++    D     
Sbjct: 356 ESALLKCVELSIGHVTEYRRRNEKIVE-IP---------FNSSNKYQVSIHETEDPDDPR 505

Query: 594 FRLFSKGASEILLKKCTNILNSNGELRGFRPRDRDDMVKKIIEPMACDGLRTICIAYRD- 652
           + L  KGA E ++ +C+ IL  NG+ +      R+      +E     GL    + + D 
Sbjct: 506 YLLVMKGAPERIMDRCSTIL-LNGKEQPLDDNFREAFNAAYLE---LGGLGERVLGFCDY 673

Query: 653 ------FSAIQEPDWDNENEVVGDLTCIAVVGIEDPVRPEVPEAIRKCQRAGITVRMVTG 706
                 F    E D +  N  +  L  + ++ + DP R  VP+A+ KC+ AGI V MVTG
Sbjct: 674 FLPVDQFPPGYEFDPEGPNFPITGLRFVGLMAMIDPPRAAVPDAVGKCRSAGIKVIMVTG 853

Query: 707 DNINTARAIAAKCGIIQPG----EDFLCLEG---KEFNRRIRN----EKGEIEQERLDKV 755
           D+  TA+AIA   GII  G    ED     G   +E + R         G++      ++
Sbjct: 854 DHPITAKAIARGVGIISEGSKTVEDIASERGIPVEEVDPREAKAAVIHGGDLRDMTPAQI 1033

Query: 756 WPKLR-----VLARSSPTDKHTLVKGIIDSTTGEQRQVVAVTGDGTNDGPALKKADVGFA 810
              LR     V AR+SP  K  +V+G        Q Q+VAVTGDG ND PALKKAD+G A
Sbjct: 1034DEILRNHSEIVFARTSPQQKLIIVEG-----CQRQGQIVAVTGDGVNDSPALKKADIGVA 1198

Query: 811 MGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNV--VAVIVAF 868
           MGIAG+DV+K+A+D+IL DDNF SIV  V  GR ++D++ K + + LT N+  ++  + F
Sbjct: 1199MGIAGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEISPFLLF 1378

Query: 869 TGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLLLRKPYGRDKPLISRTMMKN 928
             A I    PL  + +L ++L  D   +++LA E     ++ R+P  RD P+  + + + 
Sbjct: 1379ILADIPL--PLGTITILCIDLGTDMVPAISLAYEKAENDIMKRQP--RD-PVKDKLVNER 1543

Query: 929 ILGHAVYQLTII 940
           ++  A  Q+ +I
Sbjct: 1544LISMAYGQIGMI 1579
>35407
          Length = 562

 Score =  130 bits (327), Expect = 3e-30,   Method: Compositional matrix adjust.
 Identities = 84/162 (51%), Positives = 101/162 (62%), Gaps = 1/162 (0%)
 Frame = +1

Query: 58  GLCRRLKTSPTEGLADNTNDLEKRRQIYGQNFIPPKQPKTFLQLVWEALQDVTLIILEVA 117
           G  ++LKTSPTEGL  +    E+R + YG N IPPK PK+FL+LVWEALQDVTL+IL VA
Sbjct: 79  GNVQKLKTSPTEGLVGDLGK-EERVRFYGSNVIPPKPPKSFLRLVWEALQDVTLLILIVA 255

Query: 118 AIVSLGLSFY-APPGEESEACGNVSXXXXXXXXXXXXXXXXXXILLSVICVVLVTAFNDW 176
           AI+SLGLSFY     E+     +                    IL++V  VVLVTAFNDW
Sbjct: 256 AIISLGLSFYKGDEEEDETEDESYRAKADSSLEEKVGWIDGLAILVAVAVVVLVTAFNDW 435

Query: 177 SKEKQFRGLQSRIEQEQKFTVIRNGXXXXXXXXXXXXGDIAQ 218
           SKEKQFRGLQS+IE E +FTVIR+G            G+I Q
Sbjct: 436 SKEKQFRGLQSKIEHEHRFTVIRDGELHQIPVGDILVGEICQ 561
>21541
          Length = 445

 Score =  127 bits (320), Expect = 2e-29,   Method: Compositional matrix adjust.
 Identities = 68/122 (55%), Positives = 76/122 (62%)
 Frame = +3

Query: 171 TAFNDWSKEKQFRGLQSRIEQEQKFTVIRNGXXXXXXXXXXXXGDIAQVKYGDLLPADGV 230
           TAFNDWSKEKQFRGLQS+IE E +FTVIRNG            G+I Q+KYGDLLPADGV
Sbjct: 54  TAFNDWSKEKQFRGLQSKIEHEHRFTVIRNGELHQIPVGEILVGEICQIKYGDLLPADGV 233

Query: 231 LIQGNDLKIDESSLTGESDHVRKSADKDPMLLSGTHVMEGSGRMVVTAVGVNSQTGIIFT 290
           +IQ NDLK     +        K   + P          G  +MVVTAVGVNSQTGIIF 
Sbjct: 234 IIQSNDLKNRREFVNRRVGPCEKGRGQGPHAFVRHPCNGGQWKMVVTAVGVNSQTGIIFA 413

Query: 291 LL 292
           LL
Sbjct: 414 LL 419
>36566
          Length = 589

 Score =  127 bits (319), Expect = 3e-29,   Method: Compositional matrix adjust.
 Identities = 59/147 (40%), Positives = 99/147 (67%)
 Frame = +3

Query: 788 VVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYD 847
           VV +TGDG ND  ALK A++G +MG++GTDV+KEASD+IL DD+FT+I+ A+  G+ ++ 
Sbjct: 126 VVGMTGDGVNDAVALKSAEIGISMGVSGTDVSKEASDMILVDDDFTTILNAIEEGKGIFY 305

Query: 848 SISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTES 907
           +I  F++FQL+ ++ A+ +      +   +PL A+Q+LW+N+IMD   + +L  EP    
Sbjct: 306 NIRNFVRFQLSTSIAALSLIAVSTLLRLPNPLNAMQILWINIIMDGPPAQSLGVEPVDHD 485

Query: 908 LLLRKPYGRDKPLISRTMMKNILGHAV 934
           ++ + P     P+I+R ++ N+L  A+
Sbjct: 486 VIKQPPRHVGDPIITRRLIINVLSSAL 566
>08160
          Length = 459

 Score = 64.3 bits (155), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 30/59 (50%), Positives = 41/59 (69%)
 Frame = +2

Query: 432 GLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTTNRMTVVQSYL 490
           GL   VT+ L  + K+M + N LV++L+A ET+G+ + ICSDKTGTLT NRMTV   + 
Sbjct: 2   GLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWF 178
>14773
          Length = 794

 Score = 58.2 bits (139), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 32/98 (32%), Positives = 55/98 (56%)
 Frame = +2

Query: 816 TDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQ 875
           +DV+K+A+D+IL DDNF SIV  V  GR ++D++ K + + LT N+  +           
Sbjct: 2   SDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEISPFLVYILFGT 181

Query: 876 DSPLKAVQMLWVNLIMDTFASLALATEPPTESLLLRKP 913
             PL  + +L+++L  D   +++LA E     ++ R P
Sbjct: 182 PLPLGVITILFIDLGTDMVPAISLAYEMAESDIMKRPP 295
>04985
          Length = 1671

 Score = 53.9 bits (128), Expect = 4e-07,   Method: Compositional matrix adjust.
 Identities = 62/228 (27%), Positives = 101/228 (44%), Gaps = 19/228 (8%)
 Frame = -1

Query: 750  ERLDKVWPKLRVLARSSPTDKHTLVKGIIDSTTGEQRQVVAVTGDGTNDGPALKKADVGF 809
            E L KV  +  V AR +P  K  L++ +          +V + GDG ND  ALK A  G 
Sbjct: 1641 ELLPKVCTQGTVFARMAPDQKCALIENL-----QSYDYIVGMCGDGANDCEALKAAHAGI 1477

Query: 810  AMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNV---------YDSISKFLQFQLTVN 860
            ++  A   VA   +  I   +N   +V A+  GR           Y ++  F+QF     
Sbjct: 1476 SLSEAEASVAAPFTSRI---NNIECVVTAMREGRAALVTSFGCFKYMALYSFIQF----- 1321

Query: 861  VVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLLLRKPYGRDKPL 920
             ++V++ +T  C T  S L   + L+++LI+ T  ++ L      + L+      R KP 
Sbjct: 1320 -ISVLILYT--CQTNLSDL---EFLYIDLIITTTIAVLLGYTGAYDKLV------RHKPP 1177

Query: 921  ISRTMMKNILG-------HAVYQLTIIFTLLFVGELFF---DIDSGRN 958
             S   + NI+         A YQL+ +F L    +LF+   ++D  R+
Sbjct: 1176 DSLMKLSNIISILMQVTLTAAYQLSTLFYLR--SQLFYQNQEVDPLRD 1039
>28890
          Length = 552

 Score = 50.4 bits (119), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 31/86 (36%), Positives = 49/86 (56%), Gaps = 8/86 (9%)
 Frame = -3

Query: 214 GDIAQVKYGDLLPADGVLIQGNDLKIDESSLTGESDHVRKSAD---KDPM-----LLSGT 265
           GDI + K+GD +PAD  +I  +  K+D SSLTGES+   +SA+   ++P+         T
Sbjct: 412 GDIVECKFGDRVPADLRVISAHGFKVDNSSLTGESEPQSRSAEFTHENPLETRNICFFST 233

Query: 266 HVMEGSGRMVVTAVGVNSQTGIIFTL 291
           + +EG+ R +V   G ++  G I  L
Sbjct: 232 NAVEGTCRGIVIKTGDDTVMGRIANL 155
>13525
          Length = 645

 Score = 42.7 bits (99), Expect = 8e-04,   Method: Composition-based stats.
 Identities = 17/33 (51%), Positives = 26/33 (78%)
 Frame = +2

Query: 444 SVKKMMKDNNLVRHLDACETMGNATAICSDKTG 476
           + K+M + N LV++L+A ET+G+ + ICSDKTG
Sbjct: 5   TAKRMARKNCLVKNLEAVETLGSTSTICSDKTG 103
>33697
          Length = 310

 Score = 40.4 bits (93), Expect = 0.004,   Method: Composition-based stats.
 Identities = 23/49 (46%), Positives = 30/49 (61%)
 Frame = -2

Query: 681 DPVRPEVPEAIRKCQRAGITVRMVTGDNINTARAIAAKCGIIQPGEDFL 729
           DP R  VP+A+ KC+ AGI V MVTGD+  T++      G  Q G D+L
Sbjct: 195 DPPRAAVPDAVGKCRSAGIKVIMVTGDHPITSQ------GHRQRGGDYL 67
>07486
          Length = 763

 Score = 38.5 bits (88), Expect = 0.018,   Method: Compositional matrix adjust.
 Identities = 20/44 (45%), Positives = 27/44 (61%)
 Frame = -1

Query: 801 ALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRN 844
           AL +ADVG A+G  GTDVA EA+DI+L   +   +  A+   R 
Sbjct: 742 ALAQADVGIAIG-TGTDVAVEAADIVLMKSDLVDVYAAIKLSRK 614
>14321
          Length = 568

 Score = 36.6 bits (83), Expect = 0.056,   Method: Compositional matrix adjust.
 Identities = 23/55 (41%), Positives = 29/55 (52%)
 Frame = +2

Query: 757 PKLRVLARSSPTDKHTLVKGIIDSTTGEQRQVVAVTGDGTNDGPALKKADVGFAM 811
           P  RV AR +P  K  ++     +    Q  V  + GDGTND  ALK ADVG A+
Sbjct: 254 PNTRVFARVAPKQKELII-----TVLKAQGFVTLMCGDGTNDVGALKHADVGVAL 403
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6681159|ref|NP_031867.1| DEAD (Asp-Glu-Ala-Asp) box
polypeptide 6 [Mus musculus]
         (483 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

07310                                                                 399   e-111
01062                                                                 285   2e-77
09316                                                                 235   3e-62
02498                                                                 108   1e-48
00621                                                                 186   2e-47
00739                                                                 138   6e-33
00162                                                                 119   4e-32
09327                                                                 115   4e-26
04883                                                                 115   5e-26
01517                                                                 108   4e-24
22006                                                                  98   8e-21
02054                                                                  97   2e-20
08036                                                                  60   2e-19
14337                                                                  90   2e-18
19640                                                                  88   7e-18
31899                                                                  86   3e-17
34295                                                                  81   1e-15
12995                                                                  81   1e-15
19525                                                                  79   3e-15
11624                                                                  76   3e-14
00617                                                                  75   5e-14
19151                                                                  70   1e-12
17708                                                                  66   3e-11
11160                                                                  64   1e-10
30136                                                                  64   2e-10
17544                                                                  58   1e-08
33025                                                                  57   2e-08
10649                                                                  55   7e-08
39583                                                                  55   7e-08
31220                                                                  54   2e-07
33543                                                                  48   9e-06
19172                                                                  47   2e-05
12121                                                                  45   5e-05
03381                                                                  45   5e-05
11423                                                                  45   7e-05
06438                                                                  44   2e-04
34134                                                                  39   0.005
33083                                                                  38   0.011
28851                                                                  32   0.45 
>07310
          Length = 712

 Score =  399 bits (1025), Expect = e-111,   Method: Compositional matrix adjust.
 Identities = 187/237 (78%), Positives = 215/237 (90%)
 Frame = +2

Query: 225 RILDLIKKGVAKVDHVQMIVLDEADKLLSQDFVQIMEDIILTLPKNRQILLYSATFPLSV 284
           RILDL+ K + K D   ++VLDEADKLLSQDF  ++++II  LP  RQILLYSATFPLSV
Sbjct: 2   RILDLMNKRLVKPDTCGILVLDEADKLLSQDFKGMLDNIIAHLPPQRQILLYSATFPLSV 181

Query: 285 QKFMNSHLQKPYEINLMEELTLKGVTQYYAYVTERQKVHCLNTLFSRLQINQSIIFCNSS 344
           ++FM  +L+ PYEINLMEELTLKGVTQYYA+V E+QKVHCLNTLFS+LQINQSIIFCNS+
Sbjct: 182 EQFMKKYLKNPYEINLMEELTLKGVTQYYAFVQEKQKVHCLNTLFSKLQINQSIIFCNST 361

Query: 345 QRVELLAKKISQLGYSCFYIHAKMRQEHRNRVFHDFRNGLCRNLVCTDLFTRGIDIQAVN 404
           QRVELLAKKI++LGYSC+YIHAKM Q+HRNRVFHDFR GLCRNLVC+DLFTRGIDIQAVN
Sbjct: 362 QRVELLAKKITELGYSCYYIHAKMNQQHRNRVFHDFRQGLCRNLVCSDLFTRGIDIQAVN 541

Query: 405 VVINFDFPKLAETYLHRIGRSGRFGHLGLAINLITYDDRFNLKSIEEQLGTEIKPIP 461
           VVINFDFPK AETYLHRIGRSGR+GHLG+AINLIT++DRF+L  IE++LGTEIKPIP
Sbjct: 542 VVINFDFPKHAETYLHRIGRSGRYGHLGVAINLITFEDRFSLHKIEQELGTEIKPIP 712
>01062
          Length = 2138

 Score =  285 bits (730), Expect = 2e-77,   Method: Compositional matrix adjust.
 Identities = 141/369 (38%), Positives = 233/369 (63%), Gaps = 2/369 (0%)
 Frame = -3

Query: 98   FEDYCLKRELLMGIFEMGWEKPSPIQEESIPIALSGRDILARAKNGTGKSGAYLIPLLER 157
            F++  ++ ELL GI+  G+EKPS IQ+ ++   + GRD++A+A++GTGK+  + I +L+ 
Sbjct: 2073 FDNMGIREELLRGIYAYGFEKPSAIQQRAVKPIVKGRDVIAQAQSGTGKTATFSISVLQC 1894

Query: 158  LDLKKDNIQAMVIVPTRELALQVSQICIQVSKHMGGAKVMATTGGTNLRDDIMRLDDTVH 217
            LD++    QA+++ PTRELA Q+ ++ + +  +M   +  +  GGTN+ +DI +LD   H
Sbjct: 1893 LDIQLRETQALILSPTRELATQIQKVMLALGDYMN-VQCHSCIGGTNIGEDIRKLDYGQH 1717

Query: 218  VVIATPGRILDLIKKGVAKVDHVQMIVLDEADKLLSQDFVQIMEDIILTLPKNRQILLYS 277
            +V  TPGR+ D+IK+   +   ++M++LDEAD++L++ F + + D+   LP   Q++L S
Sbjct: 1716 IVSGTPGRVFDMIKRRNLRTRSIKMMILDEADEMLNKGFKEQIYDVYRYLPPATQVILIS 1537

Query: 278  ATFPLSVQKFMNSHLQKPYEINL-MEELTLKGVTQYYAYVT-ERQKVHCLNTLFSRLQIN 335
            AT P  + +  N  +  P  I +  +ELTL+G+ Q++  V  E  K   L  L+  L I 
Sbjct: 1536 ATLPHEILEMTNKFMTDPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTIT 1357

Query: 336  QSIIFCNSSQRVELLAKKISQLGYSCFYIHAKMRQEHRNRVFHDFRNGLCRNLVCTDLFT 395
            Q++IFCN+ ++V+ L +K+ +  ++   +H  M Q+ R  +   FR G  R L+ TD++ 
Sbjct: 1356 QAVIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKEREAIMKVFRAGDSRVLITTDVWA 1177

Query: 396  RGIDIQAVNVVINFDFPKLAETYLHRIGRSGRFGHLGLAINLITYDDRFNLKSIEEQLGT 455
            RGID+Q V++VIN+D P   E Y+HRIGRSGRFG  G+AIN +  DD   L+ IE+   T
Sbjct: 1176 RGIDVQQVSLVINYDLPNNRELYIHRIGRSGRFGRKGVAINFVKNDDIRILRDIEQYYST 997

Query: 456  EIKPIPSNI 464
            +I  +P N+
Sbjct: 996  QIDEMPMNV 970
>09316
          Length = 2312

 Score =  235 bits (599), Expect = 3e-62,   Method: Compositional matrix adjust.
 Identities = 131/385 (34%), Positives = 216/385 (56%), Gaps = 5/385 (1%)
 Frame = +2

Query: 91   TSTKGNEFEDYCLKRELLMGIFEMGWEKPSPIQEESIPIALSGRDILARAKNGTGKSGAY 150
             S   + F D+ LK ELL  I + G+E PS +Q E IP A+   D+L +AK+G GK+  +
Sbjct: 830  VSIHSSGFRDFLLKPELLRAIIDCGFEHPSEVQHECIPQAILSMDVLCQAKSGMGKTAVF 1009

Query: 151  LIPLLERLDLKKDNIQAMVIVPTRELALQVSQICIQVSKHMGGAKVMATTGGTNLRDDIM 210
            ++  L++L+     +  +V+  TRELA Q+S+   + SK+M   K+    GG +++ D  
Sbjct: 1010 VLATLQQLEPVDGQVSVLVMAHTRELAFQISKEYERFSKYMNNVKIAVFFGGMSVKKDEE 1189

Query: 211  RLDDTV-HVVIATPGRILDLIKKGVAKVDHVQMIVLDEADKLLSQ-DFVQIMEDIILTLP 268
             L     H+V+ TPGR+  L K     +  ++  +LDE DK+L+  D  + +++I    P
Sbjct: 1190 VLSKNCPHIVVGTPGRLHALAKANNLNLKKIKHFILDECDKMLADLDMRRDVQEIFRLTP 1369

Query: 269  KNRQILLYSATFPLSVQKFMNSHLQKPYEINLMEE--LTLKGVTQYYAYVTERQKVHCLN 326
              +Q++++SAT    ++      +Q P E+ + ++  LTL G+ Q+Y  + + +K   L 
Sbjct: 1370 HEKQVMMFSATLSKEIRPICKKFMQDPMEVYVDDDSKLTLHGLQQHYCKLKDNEKNRKLF 1549

Query: 327  TLFSRLQINQSIIFCNSSQRVELLAKKISQLGYSCFYIHAKMRQEHRNRVFHDFRNGLCR 386
             L   L+ NQ IIF  S  R   L++ + +  +    IH +M QE R   +  F++   R
Sbjct: 1550 ELLDVLEFNQVIIFVKSVPRCMALSQLLLEQNFPAIAIHRQMTQEERLSRYQQFKDFQKR 1729

Query: 387  NLVCTDLFTRGIDIQAVNVVINFDFPKLAETYLHRIGRSGRFGHLGLAINLIT-YDDRFN 445
             LV T+LF RG+DI+ VN+V N+D P+ ++TYLHR+ R+GRFG  GLAI  ++  +D   
Sbjct: 1730 ILVATNLFGRGMDIERVNIVFNYDMPEDSDTYLHRVARAGRFGTKGLAITFVSDENDAKI 1909

Query: 446  LKSIEEQLGTEIKPIPSNIDKSLYV 470
            L  ++E+    I  +P  ID S Y+
Sbjct: 1910 LNDVQERFEVNITELPDEIDISSYI 1984
>02498
          Length = 1955

 Score =  108 bits (269), Expect(2) = 1e-48,   Method: Compositional matrix adjust.
 Identities = 66/195 (33%), Positives = 118/195 (60%), Gaps = 5/195 (2%)
 Frame = +1

Query: 98  FEDYCLKRELLMGIFEMGWEKPSPIQEESIPIALSGR--DILARAKNGTGKSGAYLIPLL 155
           FE   LK +LL G+++MG+  PS IQE ++PI L+    +++A++++GTGK+ A+++ +L
Sbjct: 139 FEALNLKPQLLKGVYDMGFNAPSKIQETALPILLADPPVNMIAQSQSGTGKTAAFVLTML 318

Query: 156 ERLDLKKDNIQAMVIVPTRELALQVSQICIQVSKHMGGAKVMATTGGTNL-RDDIMRLDD 214
            R+D+ +   Q + + PT ELALQ+ ++  ++SKHM G ++     G  + R +++    
Sbjct: 319 SRVDISQTFPQCLCLAPTYELALQIGEVIEKMSKHMTGLEIRYAVRGERVNRGEVL---- 486

Query: 215 TVHVVIATPGRILDLIKKGVA-KVDHVQMIVLDEADKLLSQDFVQIMEDIILT-LPKNRQ 272
           +  +VI TPG ++D   +  A  ++ +++ VLDEAD ++S    Q     I   L    Q
Sbjct: 487 SEQIVIGTPGTVMDWSHRFKALPLEKLRVFVLDEADVMISMQGHQDQSTRIQKRLSSGCQ 666

Query: 273 ILLYSATFPLSVQKF 287
           +LL+SAT+   V +F
Sbjct: 667 MLLFSATYDQVVMQF 711

 Score =  103 bits (258), Expect(2) = 1e-48,   Method: Compositional matrix adjust.
 Identities = 60/179 (33%), Positives = 99/179 (55%), Gaps = 9/179 (5%)
 Frame = +3

Query: 291 HLQKPYEINL-MEELTLKGVTQYYAYV-TERQKVHCLNTLFSRLQINQSIIFCNSSQRVE 348
           H Q P  I+L  EE +L  + QYY    ++ +K   L  ++  + + QS+IFC+      
Sbjct: 723 HPQDPVIISLKREEESLDNIKQYYIDCNSQEEKYVALCNIYGSISVGQSMIFCHKRSTAA 902

Query: 349 LLAKKISQLGYSCFYIHAKMRQEHRNRVFHDFRNGLCRNLVCTDLFTRGIDIQAVNVVIN 408
            LA++++   ++   +  ++  E R  +   FR G  + L+ T++  RGID++ V VV+N
Sbjct: 903 WLAERMTADHHAVGLLTGELTIEQRAAIIKRFREGKEKVLITTNVSARGIDVEMVTVVVN 1082

Query: 409 FDFPKL------AETYLHRIGRSGRFGHLGLAINLITYDDRFN-LKSIEEQLGTEIKPI 460
           FD P         ETYLHRIGR+GRFG  G+AIN++        ++SIE+  G +I+ +
Sbjct: 1083FDLPVTQDWRPDCETYLHRIGRTGRFGKNGIAINMVDNSRSMAIMRSIEKHFGRKIEKL 1259
>00621
          Length = 2263

 Score =  186 bits (471), Expect = 2e-47,   Method: Compositional matrix adjust.
 Identities = 123/421 (29%), Positives = 216/421 (51%), Gaps = 48/421 (11%)
 Frame = +1

Query: 77  KLPPKDLRIKTSDVT-STKGNE-------FEDYCLKRELLMGIFEMGWEKPSPIQEESIP 128
           ++  +D RI   D   S KG         +++  L  +++  I  +G+++P+PIQ ++IP
Sbjct: 172 EMAERDWRIFREDYNISCKGGRIPNPIRFWKESDLGADIMEVIDRVGYKEPTPIQMQAIP 351

Query: 129 IALSGRDILARAKNGTGKSGAYLIPLL---------ERLDLKKDNIQAMVIVPTRELALQ 179
           I L  RDI+  A+ G+GK+ A+LIPLL         ERL+       A+++ PTRELA Q
Sbjct: 352 IGLQNRDIIGVAETGSGKTAAFLIPLLVWIQSLPKIERLEDADQGPYAVILAPTRELAQQ 531

Query: 180 VSQICIQVSKHMGGAKVMATTGGTNLRDDIMRLDDTVHVVIATPGRILDLIKKGVAKVDH 239
           + +   +  + +G  +V++  GG +  +   +L     VVIATPGR++D+++     ++ 
Sbjct: 532 IEEETRKFGEGLG-IRVVSVIGGISREEQGFKLQQGCEVVIATPGRMIDVLENRYLVLNQ 708

Query: 240 VQMIVLDEADKLLSQDFVQIMEDIILTLP-------------------------KNRQIL 274
              +V+DEAD++++  F   +  I+  LP                         K RQ +
Sbjct: 709 CTYVVMDEADRMINMGFEPEVRKILDYLPVSNQKPDNDDAEDDLKMLQNFKSKHKYRQTV 888

Query: 275 LYSATFPLSVQKFMNSHLQKP---YEINLMEELTLKGVTQYYAYVTERQKVHCLNTLFSR 331
           +++AT P  V++   + L++P   Y  N+ +   ++ V Q    +TE +K   L  + + 
Sbjct: 889 MFTATMPPQVERLARTFLRRPTVVYIGNVGK--PVERVEQIVYMLTESEKRKKLIEVLNA 1062

Query: 332 LQINQSIIFCNSSQRVELLAKKISQLGYSCFYIHAKMRQEHRNRVFHDFRNGLCRNLVCT 391
                 IIF N  +  ++LAK + ++G++   +H    QE R       + G    +V T
Sbjct: 1063GVDPPIIIFVNQKKGADVLAKSLEKMGFNATTLHGGKGQEQREYALASLKGGAKDIMVAT 1242

Query: 392 DLFTRGIDIQAVNVVINFDFPKLAETYLHRIGRSGRFGHLGLAINLITYDDR---FNLKS 448
           D+  RGIDI+ V++V+N+D  +  E Y HRIGR+GR G  G +I  +T +D    ++LK 
Sbjct: 1243DVAGRGIDIKDVSLVLNYDMARTIEDYTHRIGRTGRAGKEGTSITFLTKEDSMVFYDLKQ 1422

Query: 449 I 449
           +
Sbjct: 1423L 1425
>00739
          Length = 1313

 Score =  138 bits (347), Expect = 6e-33,   Method: Compositional matrix adjust.
 Identities = 83/251 (33%), Positives = 133/251 (52%), Gaps = 6/251 (2%)
 Frame = +3

Query: 217 HVVIATPGRILDLIKK-GVAKVDHVQMIVLDEADKLLSQDFVQIMEDIILTLPKNRQILL 275
           H+VI+TPGR+ D I       +  V+ +V+DEAD+LL  +F   +E I+  LP  RQ LL
Sbjct: 45  HIVISTPGRLADHIDSCDTFSLKRVKFLVMDEADRLLDDNFGAQLEPILTRLPSARQTLL 224

Query: 276 YSATFPLSVQKFMNSHLQKPY-EINLMEELTLKGVTQYYAYVTERQK----VHCLNTLFS 330
           +SAT   +V    +S L KP+  I   E  T+  + + Y  V    K    VH L+    
Sbjct: 225 FSATLSPTVNALRDSVLNKPFVWIQQSERATVDELQEDYVLVPASMKDAYMVHILDHWLK 404

Query: 331 RLQINQSIIFCNSSQRVELLAKKISQLGYSCFYIHAKMRQEHRNRVFHDFRNGLCRNLVC 390
               +  IIF  + +  ++L   + +L +SC  +H+ + Q  R      F++   R L+ 
Sbjct: 405 DHPRSSLIIFTXTCKYAQILGMMLEKLQFSCAVLHSMIPQRFRLSSLSRFKSNQTRILIS 584

Query: 391 TDLFTRGIDIQAVNVVINFDFPKLAETYLHRIGRSGRFGHLGLAINLITYDDRFNLKSIE 450
           TD+ +RG+DI  V+++IN + P     Y+HR+GR+ R G  G +I+L+T  D   +KSIE
Sbjct: 585 TDVASRGLDIPTVDLIINHNIPNRPRDYVHRVGRTARAGRCGQSISLVTEFDIKLIKSIE 764

Query: 451 EQLGTEIKPIP 461
             +  ++   P
Sbjct: 765 SHINCQMTEHP 797
>00162
          Length = 2322

 Score =  119 bits (299), Expect(2) = 4e-32,   Method: Compositional matrix adjust.
 Identities = 92/313 (29%), Positives = 154/313 (49%), Gaps = 11/313 (3%)
 Frame = +3

Query: 165 IQAMVIVPTRELALQVSQICIQVSKHMGGAKVMATTGGTNLRDDIMRLDDTVHVVIATPG 224
           ++A++I PTRELA Q+ ++  ++      +  +   G    R+    L    ++VI T G
Sbjct: 138 MEALIITPTRELAFQIYEVLNKIRTFHDFSANLVIGGKFMWRET--HLMGKTNIVICTVG 311

Query: 225 RILDLIKKGVA-KVDHVQMIVLDEADKLLSQDFVQIMEDIILTLPKNRQILLYSATFPLS 283
           R+L  ++   A  V  ++++VLDEAD+++   F Q M+ I+  LP  RQ LL+SAT  +S
Sbjct: 312 RLLHHLESTQAFDVSELKVLVLDEADRIMDSKFAQDMDSIMSHLPP-RQTLLFSATQTMS 488

Query: 284 VQKFMNSHLQKPYEINL---MEELTLKGVTQYYAYVTERQKVHCLNTLFSRLQINQSIIF 340
           V+      L+ P  +++    E +T  G+ Q Y      +K+  L +       N+ ++F
Sbjct: 489 VKTLARLSLKDPSYVSVDRHAEYVTPTGLEQSYIVCELHEKLSLLYSFLKNHPNNKIMVF 668

Query: 341 ---CNSSQRVELLAKKISQLGYSCFYIHAKMRQEHRNRVFHDFRNGLCRN----LVCTDL 393
              C  ++ V  + K+  + G S   +H  + Q  R  ++ +F    CR     L+ TDL
Sbjct: 669 LQTCKQARYVHTVIKR-ERPGMSVLVLHGGIPQLRRLDIYREF----CRKQHVILITTDL 833

Query: 394 FTRGIDIQAVNVVINFDFPKLAETYLHRIGRSGRFGHLGLAINLITYDDRFNLKSIEEQL 453
             RG+D  AVN VI  D P    TY+HR GR+ RF   G A+ ++   +  ++     + 
Sbjct: 834 ACRGLDFPAVNWVIQLDCPVDVNTYIHRAGRTARFECNGQALLVLLPSEEEHMVEALHRK 1013

Query: 454 GTEIKPIPSNIDK 466
              IK I  N  K
Sbjct: 1014KIPIKKISVNTKK 1052

 Score = 36.6 bits (83), Expect(2) = 4e-32,   Method: Compositional matrix adjust.
 Identities = 19/38 (50%), Positives = 26/38 (68%)
 Frame = +2

Query: 129 IALSGRDILARAKNGTGKSGAYLIPLLERLDLKKDNIQ 166
           +A  G D+L  AK G+GK+ A+LIP+LE L  K+D I 
Sbjct: 20  LACRGLDVLGAAKTGSGKTLAFLIPILETLS-KQDIIS 130
>09327
          Length = 1087

 Score =  115 bits (288), Expect = 4e-26,   Method: Compositional matrix adjust.
 Identities = 68/237 (28%), Positives = 125/237 (52%), Gaps = 6/237 (2%)
 Frame = +2

Query: 168 MVIVPTRELALQVSQICIQVSKHMGGAKVMATTGGTNLRDDIMRLDDTVHVVIATPGRIL 227
            ++VPTRELA QV ++ ++   H    + +   GG      +  LD    + IATPGR++
Sbjct: 17  WLLVPTRELAQQVQEVAVEFG-HSSRVRSVCVYGGAQRGPQLRELDRGAEICIATPGRLI 193

Query: 228 DLIKKGVAKVDHVQMIVLDEADKLLSQDFVQIMEDIILTLPKNRQILLYSATFPLSVQKF 287
           D ++     +     +VLDEAD++L   F   +  I+  +  +RQ L++SAT+P  V+K 
Sbjct: 194 DFLESNRTNLRRCTYLVLDEADRMLDMGFEPQIRKIVEQIRPDRQTLMWSATWPKEVRKL 373

Query: 288 MNSHLQKPYEINLME-ELT-----LKGVTQYYAYVTERQKVHCLNTLFSRLQINQSIIFC 341
               + +  +IN+   +LT     L+ +     +  E + V  LN +    + N+++IF 
Sbjct: 374 AEDFIMEYTQINIGALQLTANHNILQIIDVCMDHEKEEKLVKLLNEIMQEKE-NRTLIFV 550

Query: 342 NSSQRVELLAKKISQLGYSCFYIHAKMRQEHRNRVFHDFRNGLCRNLVCTDLFTRGI 398
            + ++ + + +++ + G+    IH    Q+ R+ V +DFRNG C  L+ TD+ +RG+
Sbjct: 551 ETKRKCDDIHRRMKRDGWPVLCIHGDKSQQERDWVLNDFRNGRCPVLLATDVASRGL 721
>04883
          Length = 1155

 Score =  115 bits (287), Expect = 5e-26,   Method: Compositional matrix adjust.
 Identities = 73/261 (27%), Positives = 132/261 (50%), Gaps = 11/261 (4%)
 Frame = +3

Query: 98  FEDYCLKRELLMGIFEMGWEKPSPIQEESIPIALSGRDILARAKNGTGKSGAYLIPLLER 157
           F DY + +     +    W  P+PIQ +S P+A++G+D++  A+ G+GK+ A+++P +  
Sbjct: 381 FPDYVMNQ-----VRRNSWTAPTPIQSQSWPVAMAGKDLVGIAQTGSGKTLAFMLPAIVH 545

Query: 158 LDL-----KKDNIQAMVIVPTRELALQVSQICIQVSKHMGGAKVMATTGGTNLRDDIMRL 212
           ++      + D    + +VPTRELA QV ++  Q   H    + +   GG      +  L
Sbjct: 546 INHQAYLERGDGPIVLALVPTRELAQQVQEVA-QEFGHASRVRSVCVYGGAPRGPQLRDL 722

Query: 213 DDTVHVVIATPGRILDLIKKGVAKVDHVQMIVLDEADKLLSQDFVQIMEDIILTLPKNRQ 272
           +    + IATPGR++D ++     +     +VLDEAD++L   F   +  II  +  +RQ
Sbjct: 723 ERGAEICIATPGRLIDFLESNRTNLRRCTYLVLDEADRMLDMGFEPQIRKIIEQIRPDRQ 902

Query: 273 ILLYSATFPLSVQKFMNSHLQKPYEINLME-ELTLK-GVTQYYAYVTERQK----VHCLN 326
            L++SAT+P  V+K     + +  ++N+   ELT    + Q      E +K    V  LN
Sbjct: 903 TLMWSATWPKEVRKLAEDFIDEYVQVNIGALELTANHNILQIIDVCMEHEKEDKLVKLLN 1082

Query: 327 TLFSRLQINQSIIFCNSSQRV 347
            + +R +  +   FC   +++
Sbjct: 1083EIMTRKKRTKP-SFCGDQEKM 1142
>01517
          Length = 2605

 Score =  108 bits (271), Expect = 4e-24,   Method: Compositional matrix adjust.
 Identities = 75/251 (29%), Positives = 119/251 (47%), Gaps = 8/251 (3%)
 Frame = +2

Query: 227 LDLIKKGVAKVDHVQMIVLDEADKLLSQDFV----QIMEDIILTLPKNRQILLYSATFPL 282
           +D++++G   +DH   +VLDEAD++L   F     +I+E   +     RQ L++SATFP 
Sbjct: 2   VDMMERGKIGMDHCNYLVLDEADRMLDMGFEPQIRRIVEKDTMPPTGQRQTLMFSATFPK 181

Query: 283 SVQKFMNSHLQKPYEINLME-ELTLKGVTQYYAYVTERQKVHCLNTLFSRLQINQ---SI 338
            +Q      L     + +     T + +TQ   +V E +K   L  L           ++
Sbjct: 182 EIQLLARDFLDNYIFLAVGRVGSTSENITQKVVWVEEPEKRSFLLDLLMASGTGPESLTL 361

Query: 339 IFCNSSQRVELLAKKISQLGYSCFYIHAKMRQEHRNRVFHDFRNGLCRNLVCTDLFTRGI 398
           +F  + +  + L + +    Y    IH    Q  R      F+NG    LV T +  RG+
Sbjct: 362 VFVETKKGADSLEQFLMYENYPATSIHGDRSQREREDALRVFKNGDRPILVATAVAARGL 541

Query: 399 DIQAVNVVINFDFPKLAETYLHRIGRSGRFGHLGLAINLITYDDRFNLKSIEEQLGTEIK 458
           DI  V  VINFD P   E Y+HRIGR+GR G+LGLA +     +R   + + + L    +
Sbjct: 542 DIPNVRHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNDKNRNIARDMLDLLTEANQ 721

Query: 459 PIPSNIDKSLY 469
            +PS ++   Y
Sbjct: 722 EVPSWLESLAY 754
>22006
          Length = 3414

 Score = 97.8 bits (242), Expect = 8e-21,   Method: Compositional matrix adjust.
 Identities = 48/135 (35%), Positives = 82/135 (60%), Gaps = 1/135 (0%)
 Frame = +2

Query: 119  PSPIQEESIPIALSGRDILARAKNGTGKSGAYLIPLLERLDL-KKDNIQAMVIVPTRELA 177
            P+PIQ ++IP+ + G+D++A A+ G+GK+ A+L+P+LERL +      +A+++ PTRELA
Sbjct: 3005 PTPIQRKTIPVIMEGKDMVAMARTGSGKTAAFLVPMLERLKMHSSKGARALILSPTRELA 3184

Query: 178  LQVSQICIQVSKHMGGAKVMATTGGTNLRDDIMRLDDTVHVVIATPGRILDLIKKGVAKV 237
            LQ  +   ++ K +   +     GG  + D    L     ++IATPGR+L ++ +    +
Sbjct: 3185 LQTLKFTKELGKFL-DLRAAVILGGDRMEDQFSALHQNPDIIIATPGRLLHVLVEMKKSL 3361

Query: 238  DHVQMIVLDEADKLL 252
              V  +V DEAD+L 
Sbjct: 3362 KEVIYVVFDEADRLF 3406
>02054
          Length = 1110

 Score = 97.1 bits (240), Expect = 2e-20,   Method: Compositional matrix adjust.
 Identities = 57/200 (28%), Positives = 107/200 (53%), Gaps = 4/200 (2%)
 Frame = -3

Query: 281 PLSVQKFMNSHLQKPYEINLMEEL-TLKGVTQYYAYVTERQKVHCLNTLFSRLQINQSII 339
           P+   K   + L+ P ++ +  +  T+  + Q Y ++  + K   L ++ + L  N  ++
Sbjct: 802 PIRWPKLQRASLRDPVKVEVSNKYQTVDTLQQSYLFIPAKYKDAYLVSILNELAGNSFMV 623

Query: 340 FCNS---SQRVELLAKKISQLGYSCFYIHAKMRQEHRNRVFHDFRNGLCRNLVCTDLFTR 396
           FC++   +QRV LL   +  LG++   +H +M Q  R    + F++     L+ TD+ +R
Sbjct: 622 FCSTCANTQRVALL---LRNLGFTAIPLHGQMSQAKRLGSLNKFKSKDRSILIATDVASR 452

Query: 397 GIDIQAVNVVINFDFPKLAETYLHRIGRSGRFGHLGLAINLITYDDRFNLKSIEEQLGTE 456
           G+DI  V+VV+N D P  ++ Y+HR+GR+ R G  G AI  ++  D    + IE  +G +
Sbjct: 451 GLDIPHVDVVLNLDIPTHSKDYMHRVGRTARAGRSGRAITFVSQYDVELYQRIEHLIGKK 272

Query: 457 IKPIPSNIDKSLYVAEYHSE 476
           +   P+  D+ + +AE  +E
Sbjct: 271 LSEYPTEKDQVMQLAERVAE 212

 Score = 52.4 bits (124), Expect = 4e-07,   Method: Compositional matrix adjust.
 Identities = 30/96 (31%), Positives = 55/96 (57%), Gaps = 2/96 (2%)
 Frame = -2

Query: 202  GTNLRDDIMRLDDTVHVVIATPGRILDLIK--KGVAKVDHVQMIVLDEADKLLSQDFVQI 259
            G ++    + L    H++IATPGR++D ++  KG + +  ++ +V+DEAD++L  +F   
Sbjct: 1043 GIDMSTQALMLGKKPHIIIATPGRLVDHLENTKGFS-LRALKFLVMDEADRILDMNFQDE 867

Query: 260  MEDIILTLPKNRQILLYSATFPLSVQKFMNSHLQKP 295
            ++ I+  +P+ R   L+SAT    V K   S  + P
Sbjct: 866  VDKILKVIPRERNTYLFSATMTNKVAKTTASITEGP 759
>08036
          Length = 1226

 Score = 60.5 bits (145), Expect(2) = 2e-19,   Method: Compositional matrix adjust.
 Identities = 29/68 (42%), Positives = 43/68 (63%)
 Frame = +3

Query: 395 TRGIDIQAVNVVINFDFPKLAETYLHRIGRSGRFGHLGLAINLITYDDRFNLKSIEEQLG 454
            RGID Q V+ VINF+FPK  + Y+HR+GR+ R    G A++LI+  +    +++EE   
Sbjct: 612 ARGIDFQNVSNVINFEFPKTVDAYIHRVGRTARGDKQGCALSLISRHENDQFEAVEEAQK 791

Query: 455 TEIKPIPS 462
           T+ K  PS
Sbjct: 792 TD-KDSPS 812

 Score = 53.5 bits (127), Expect(2) = 2e-19,   Method: Compositional matrix adjust.
 Identities = 46/177 (25%), Positives = 78/177 (44%), Gaps = 3/177 (1%)
 Frame = +1

Query: 219 VIATPGRILDLIKKGVAKVDHVQMIVLDEADKLLSQDFVQIMEDIILTLPKNRQILLYSA 278
           V+ TP RIL  ++ G  ++  VQM+V+DEAD + S      M+ ++  LP+  Q  L SA
Sbjct: 1   VVGTPSRILAHLRAGHLELHTVQMLVVDEADLVFSFGHEADMKKLMEELPRIYQAFLMSA 180

Query: 279 TFPLSVQKFMNSHLQKPYEINLMEELTLKG--VTQYYAYVTERQKVHCLNTLFSR-LQIN 335
           T    V+      L  P  + L E    +   +TQY+       K   +  +    L   
Sbjct: 181 TLSEDVKALKKMVLHNPVILKLKESQLPESTQLTQYHVKCEVDDKFTLMVAVLKLGLVRG 360

Query: 336 QSIIFCNSSQRVELLAKKISQLGYSCFYIHAKMRQEHRNRVFHDFRNGLCRNLVCTD 392
           +SI+F NS      L   +   G     +++++  + R  +   F  GL   ++ +D
Sbjct: 361 KSILFVNSVDSCYKLKLFLEPFGIPACVLNSELPVKSRCHIVSQFNEGLYDIIIASD 531
>14337
          Length = 693

 Score = 90.1 bits (222), Expect = 2e-18,   Method: Compositional matrix adjust.
 Identities = 50/133 (37%), Positives = 70/133 (52%)
 Frame = +2

Query: 317 TERQKVHCLNTLFSRLQINQSIIFCNSSQRVELLAKKISQLGYSCFYIHAKMRQEHRNRV 376
           +E  K+  +  LF+       ++F  S QR + L  +     +    IHA   Q  R+  
Sbjct: 5   SEAGKLMAMRNLFTEGITPPVLVFVQSKQRAKELYSEFMFDKHKVDAIHADKPQAERDAT 184

Query: 377 FHDFRNGLCRNLVCTDLFTRGIDIQAVNVVINFDFPKLAETYLHRIGRSGRFGHLGLAIN 436
              F  G    LVCT+L  RGID + +N+VIN+DFP  A +Y+HRIGR+GR G  G AI 
Sbjct: 185 VRAFTEGRVWVLVCTELMGRGIDFKGINLVINYDFPTNAVSYIHRIGRTGRAGVPGRAIT 364

Query: 437 LITYDDRFNLKSI 449
             T  D  +L+SI
Sbjct: 365 FFTEQDVTHLRSI 403
>19640
          Length = 456

 Score = 88.2 bits (217), Expect = 7e-18,   Method: Compositional matrix adjust.
 Identities = 38/88 (43%), Positives = 56/88 (63%)
 Frame = -1

Query: 339 IFCNSSQRVELLAKKISQLGYSCFYIHAKMRQEHRNRVFHDFRNGLCRNLVCTDLFTRGI 398
           IFCN+ ++V+ L +++S   ++   +H  M Q  R  +   FR+G  R L+ TDL  RGI
Sbjct: 456 IFCNTRRKVDQLTQEMSSHNFTVSAMHGDMEQRDREVIMKQFRSGSSRVLITTDLLARGI 277

Query: 399 DIQAVNVVINFDFPKLAETYLHRIGRSG 426
           D+Q V++VIN+D P   E Y+HRIGR G
Sbjct: 276 DVQQVSLVINYDLPSNRENYIHRIGRGG 193

 Score = 42.7 bits (99), Expect = 4e-04,   Method: Composition-based stats.
 Identities = 25/47 (53%), Positives = 30/47 (63%), Gaps = 1/47 (2%)
 Frame = -3

Query: 419 LHRIGRSG-RFGHLGLAINLITYDDRFNLKSIEEQLGTEIKPIPSNI 464
           LH   RS  RFG  G+AIN IT DDR  LK IE+   T I+ +P+NI
Sbjct: 220 LHS*NRSRWRFGRKGVAINFITDDDRRILKDIEQFYHTTIEEMPANI 80
>31899
          Length = 453

 Score = 85.9 bits (211), Expect = 3e-17,   Method: Compositional matrix adjust.
 Identities = 40/125 (32%), Positives = 75/125 (60%)
 Frame = -1

Query: 84  RIKTSDVTSTKGNEFEDYCLKRELLMGIFEMGWEKPSPIQEESIPIALSGRDILARAKNG 143
           + +T+DV +++  +F    L + +L G+   G+E+PSPIQ ++IP+   G D++ +AK+G
Sbjct: 381 KARTNDVMTSESVDFASLLLSKPVLNGLKNAGFERPSPIQLKAIPLGRCGLDLIVQAKSG 202

Query: 144 TGKSGAYLIPLLERLDLKKDNIQAMVIVPTRELALQVSQICIQVSKHMGGAKVMATTGGT 203
           TGK+  + +  LE ++    + Q +V+ PTRE+ALQ+ ++   +   M G +     GG 
Sbjct: 201 TGKTCVFSVVALEGIETTARSTQVLVLAPTREIALQIWEVINSIGSAMSGLQCHTFIGGL 22

Query: 204 NLRDD 208
            + +D
Sbjct: 21  PVHED 7
>34295
          Length = 694

 Score = 80.9 bits (198), Expect = 1e-15,   Method: Compositional matrix adjust.
 Identities = 42/130 (32%), Positives = 74/130 (56%), Gaps = 1/130 (0%)
 Frame = -1

Query: 333 QINQSIIFCNSSQRVELLAKKISQLGYSCFYIHAKMRQEHRNRVFHDFRNGLCRNLVCTD 392
           +I   +IF N+ +  +LL+  ++ +      +H  MRQ+ R      F++   R L+ TD
Sbjct: 547 KIPNVMIFTNTKKYCQLLSMTLTNMEIENVCLHGFMRQKERVSALSRFKSNHIRTLIATD 368

Query: 393 LFTRGIDIQAVNVVINFDFPKLAETYLHRIGRSGRFGHLGLAINLITY-DDRFNLKSIEE 451
           +  RG+DI +V +VIN   P+  + Y+HR+GR+ R G  G+AI++  +  D   L +IEE
Sbjct: 367 VAARGLDIPSVQLVINHMLPRTPKEYIHRVGRTARAGRKGVAISIFRFPRDLELLGAIEE 188

Query: 452 QLGTEIKPIP 461
           ++ T++   P
Sbjct: 187 EINTKLTEHP 158
>12995
          Length = 1072

 Score = 80.9 bits (198), Expect = 1e-15,   Method: Compositional matrix adjust.
 Identities = 40/127 (31%), Positives = 69/127 (54%)
 Frame = +3

Query: 337 SIIFCNSSQRVELLAKKISQLGYSCFYIHAKMRQEHRNRVFHDFRNGLCRNLVCTDLFTR 396
           +++F  +   VE L   +++ G +C YI++ + Q  R      F +   + ++ TDL  R
Sbjct: 138 TVVFVATKHHVEYLNTLLTKCGIACTYIYSSLDQTARKIHVAKFTHKQVKVMLVTDLAAR 317

Query: 397 GIDIQAVNVVINFDFPKLAETYLHRIGRSGRFGHLGLAINLITYDDRFNLKSIEEQLGTE 456
           GIDI  ++ V+NF FP  A+ ++HR+GR  R G  G A +L+  D+  +L  +   LG  
Sbjct: 318 GIDIPQLDNVVNFHFPAKAKLFVHRVGRVARAGRSGTAYSLVAMDEVAHLVDLHVFLGRP 497

Query: 457 IKPIPSN 463
           +K  P +
Sbjct: 498 LKTAPQS 518
>19525
          Length = 585

 Score = 79.3 bits (194), Expect = 3e-15,   Method: Compositional matrix adjust.
 Identities = 53/185 (28%), Positives = 104/185 (56%), Gaps = 5/185 (2%)
 Frame = +2

Query: 161 KKDNIQAMVIVPTRELALQVSQICIQVSKHMGGAKVMATTGGTNLRDDIMRLDDTVHVVI 220
           ++   + +V+VPTRELA+QV Q+  Q+S++   +  +A  GG +++     L     +V+
Sbjct: 2   ERATTRVLVLVPTRELAVQVYQVGQQISQYTKISICLAA-GGLDIKGQEAALRLCPDIVV 178

Query: 221 ATPGRILDLIKKGVA-KVDHVQMIVLDEADKLLSQDFVQIMEDIILTLPKNRQILLYSAT 279
           ATPGR++D +       + HV+++VLDEAD++L + F   M +II      RQ +L+SAT
Sbjct: 179 ATPGRLIDHLHNAPNFTIAHVEILVLDEADRMLDEYFAAQMTEIIRMCNFQRQTMLFSAT 358

Query: 280 FPLSVQKFMNSHLQKPYEINLMEELTLK-GVTQYYAYVTERQ---KVHCLNTLFSRLQIN 335
              +VQ   +  L++  ++ + +   +  G+ Q +  + E +   +   +++L SR   +
Sbjct: 359 MSDAVQDLASVSLKEAVKVFVNQNTDIALGLQQEFVRIRENKEGDREAIVSSLVSRTFCD 538

Query: 336 QSIIF 340
           + ++F
Sbjct: 539 KCMVF 553
>11624
          Length = 2257

 Score = 76.3 bits (186), Expect = 3e-14,   Method: Compositional matrix adjust.
 Identities = 46/153 (30%), Positives = 75/153 (49%), Gaps = 3/153 (1%)
 Frame = -1

Query: 305 TLKGVTQYYAYVTERQKVHCLNTLFSRLQINQSIIFCNS---SQRVELLAKKISQLGYSC 361
           T +G+T+Y       +K   +      L+    + F NS   + R+ LL K    L    
Sbjct: 991 TPEGLTEYIVESDSSEKPLLVLHFLHNLKFRSVLCFTNSVETTHRLCLLVKLYGGLSVKE 812

Query: 362 FYIHAKMRQEHRNRVFHDFRNGLCRNLVCTDLFTRGIDIQAVNVVINFDFPKLAETYLHR 421
           F   +++  E R ++   F  G    LVC+D   RG+D+  V  VI++D P   +TY+HR
Sbjct: 811 F--SSRLPGERRKKILKQFSKGKIDLLVCSDAMARGMDVDNVKYVISYDNPPYIKTYIHR 638

Query: 422 IGRSGRFGHLGLAINLITYDDRFNLKSIEEQLG 454
           +GR+ R G  G AI+L+   + F+ K +  + G
Sbjct: 637 VGRTARAGRAGTAISLLEKKEFFHFKQMMREAG 539

 Score = 65.1 bits (157), Expect = 6e-11,   Method: Compositional matrix adjust.
 Identities = 67/257 (26%), Positives = 114/257 (44%), Gaps = 28/257 (10%)
 Frame = -3

Query: 43   NQLKNTSTINNGTPQQAQSMAATIKPGDDWKKTLKLPPKDLRIKTSDVTSTKGNEFEDYC 102
            N +   S + N T   A+ +   +    DW  T  +    L+    D    +  E     
Sbjct: 2120 NAIGGFSXLGNFTHDNARPVKRKLP---DWLATPTIIGGALKKHRHDTDLKEEGEDNMSV 1950

Query: 103  LKRELLMGIFEMGWEKPSPIQEESIP--------------IALSGRDILARAKNGTGKSG 148
            L  +L   + + G ++  P+Q E IP                L  RDI   A  G+GK+ 
Sbjct: 1949 LDDQLRGKLHDSGIDRLFPVQREFIPELWKDVRYSLTAGRYGLRPRDICVSAPTGSGKTL 1770

Query: 149  AYLIPLLERLDLKK-DNIQAMVIVPTRELALQVSQICIQVSKHMGGAKVMATTGGT--NL 205
            AY +P+++ L  +   +++A++++P R+LA QV Q+           KV    G T  N+
Sbjct: 1769 AYTLPIIQCLKQRMVPHVRAVIVLPVRDLAEQVYQVFCHYCADT-PLKVGIVVGKTVFNV 1593

Query: 206  RDDIM---RLDDTVHVVI----ATPGRILDLIKKGVA-KVDHVQMIVLDEADKLLSQ--- 254
              D +   R     H VI    ATPGR++D I       + H++ +V+DEAD+++     
Sbjct: 1592 EQDTLVKKRYGGVYHSVIDILVATPGRLVDHINSTPGFDLSHLRFLVIDEADRMMEDIKL 1413

Query: 255  DFVQIMEDIILTLPKNR 271
            D++ ++E    T P +R
Sbjct: 1412 DWLSVVETAAFT-PTHR 1365
>00617
          Length = 1505

 Score = 75.1 bits (183), Expect = 5e-14,   Method: Compositional matrix adjust.
 Identities = 36/108 (33%), Positives = 62/108 (57%)
 Frame = -3

Query: 354  ISQLGYSCFYIHAKMRQEHRNRVFHDFRNGLCRNLVCTDLFTRGIDIQAVNVVINFDFPK 413
            + +L +SC  +H+ + Q  R      F++   R L+ TD+ +RG+DI  V+++IN + P 
Sbjct: 1497 LEKLQFSCAVLHSMIPQRFRLSSLSRFKSNQTRILISTDVASRGLDIPTVDLIINHNIPN 1318

Query: 414  LAETYLHRIGRSGRFGHLGLAINLITYDDRFNLKSIEEQLGTEIKPIP 461
                Y+HR+GR+ R G  G +I+L+T  D   +KSIE  +  ++   P
Sbjct: 1317 RPRDYVHRVGRTARAGRCGQSISLVTEFDIKLIKSIESHINCQMTEHP 1174
>19151
          Length = 625

 Score = 70.5 bits (171), Expect = 1e-12,   Method: Compositional matrix adjust.
 Identities = 36/77 (46%), Positives = 51/77 (66%), Gaps = 7/77 (9%)
 Frame = -3

Query: 388 LVCTDLFTRGIDIQAVNVVINFDFP------KLAETYLHRIGRSGRFGHLGLAINLITYD 441
           L+ T++ +RGIDI+ V +V+NFD P         ETYLHRIGR+GRFG  G+AINLI  +
Sbjct: 617 LITTNVLSRGIDIEQVTIVVNFDLPIDLRGNADCETYLHRIGRTGRFGKSGIAINLIDGE 438

Query: 442 DRFNL-KSIEEQLGTEI 457
              N+ ++IE+    +I
Sbjct: 437 KSMNVCRAIEKHFQKDI 387
>17708
          Length = 882

 Score = 65.9 bits (159), Expect = 3e-11,   Method: Compositional matrix adjust.
 Identities = 35/101 (34%), Positives = 61/101 (60%), Gaps = 6/101 (5%)
 Frame = +1

Query: 134 RDILARAKNGTGKSGAYLIPLLERLD----LKKDNIQAMVIVPTRELALQVSQICIQVSK 189
           RD++  AK G+GK+ A+LIP +E +     + ++    ++I PTREL++Q   +  ++ K
Sbjct: 553 RDLMGAAKTGSGKTLAFLIPAIELMYKLKFMPRNGTGCIIISPTRELSMQTFNVLTELLK 732

Query: 190 --HMGGAKVMATTGGTNLRDDIMRLDDTVHVVIATPGRILD 228
             H     +M   GG N  D++ +L   V++++ATPGR+LD
Sbjct: 733 YHHHTFGLIM---GGVNRHDEVKKLKKGVNIIVATPGRLLD 846
>11160
          Length = 646

 Score = 64.3 bits (155), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 53/191 (27%), Positives = 92/191 (48%), Gaps = 17/191 (8%)
 Frame = -1

Query: 201 GGTNLRDDIMR-LDDTVHVVIATPGRILDLIKKG------VAKVDHVQMIVLDEADKLLS 253
           GG +   DI + +     ++IATPGR+ DL  +        A V  ++++VLDEAD+LL 
Sbjct: 646 GGVSCSHDISKFMKSGGSILIATPGRLDDLFSRKESGFNLAASVKALEVLVLDEADRLLD 467

Query: 254 QDFVQIMEDIILTLPKNRQILLYSATFPLSVQKFMNSHLQKPYEINLME--------ELT 305
             F   +  I+  LPK R+  L+SAT    V+  + + L+ P  + + E        + T
Sbjct: 466 MGFEASINTILGHLPKLRRTGLFSATQTDEVENLIRAGLRNPLRVTVKEKKLAGEADQRT 287

Query: 306 LKGVTQYYAYVTERQKVHCLNTLFSRLQINQSIIFCNSSQRVELLAKKISQL--GYSCFY 363
              ++ YY  V   +K   L         ++ ++F ++   V+  +  ++QL        
Sbjct: 286 PSTLSNYYMIVEAEEKFSQLVKFLKTHHRDKLLLFFSTCACVDYFSMCLTQLLKHMQVLS 107

Query: 364 IHAKMRQEHRN 374
           IH+KM+Q+ RN
Sbjct: 106 IHSKMKQK-RN 77
>30136
          Length = 524

 Score = 63.5 bits (153), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 40/134 (29%), Positives = 68/134 (50%), Gaps = 8/134 (5%)
 Frame = +2

Query: 97  EFEDYCLKRELLMGIFEMGWEKPSPIQEESIPIALSGRDILARAKNGTGKSGAYLIPLLE 156
           +F +  L   ++  I   G++ P+PIQ +  PIA+SG + +  AK G+GK+  Y++P + 
Sbjct: 134 DFAEAYLPDYVIKEIRRQGYKSPTPIQAQGWPIAMSGANFVGIAKTGSGKTLGYILPAIV 313

Query: 157 RLD-----LKKDNIQAMVIVPTRELALQVSQICIQVSKHMGGAKVMATT---GGTNLRDD 208
            ++      + +   A+V+ PTRELA Q+     QV+   G +  +  T   GG      
Sbjct: 314 HINNQQPLQRGEGPIALVLAPTRELAQQIQ----QVATEFGSSSYVRNTCVFGGAPKGGQ 481

Query: 209 IMRLDDTVHVVIAT 222
           +  L     +VIAT
Sbjct: 482 MRDLQRGCEIVIAT 523
>17544
          Length = 1047

 Score = 57.8 bits (138), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 42/150 (28%), Positives = 74/150 (49%), Gaps = 19/150 (12%)
 Frame = +2

Query: 87  TSDVTSTKGNEFEDYCLKRELLMGIFEMGWEKPSPIQEESIPIALSGRDILARAKNGTGK 146
           T D      N FE+  L   +   I    + KP+P+Q+ ++PI L  RD++A A+ G+GK
Sbjct: 605 TGDSPPPHINSFEECTLGEIIRNNIVLSKYNKPTPVQKFALPIVLGKRDLMACAQTGSGK 784

Query: 147 SGAYLIPLLERL--------DLKKDNIQ---------AMVIVPTRELALQVSQICIQVSK 189
           + A+L+P+L ++         L+++  +         A+++ PTRELA   SQI  +  K
Sbjct: 785 TAAFLLPILNQVYENGPTPEALQQNQSRGYRRKMYPIALILAPTRELA---SQIYDEARK 955

Query: 190 HMGGAKVMATT--GGTNLRDDIMRLDDTVH 217
               +++      GG ++   +  LD   H
Sbjct: 956 FAYRSRLRPCVVYGGADIGAQMRDLDKGCH 1045
>33025
          Length = 558

 Score = 57.0 bits (136), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 43/148 (29%), Positives = 69/148 (46%), Gaps = 5/148 (3%)
 Frame = +3

Query: 201 GGTNLRDDIMRLDDTVHVVIATPGRILDLIKKGVAKVDHVQMIVLDEADKLLSQDF---V 257
           G T+ R    R+    ++V+ TPGR+LD I      +   Q ++LDEAD++L   F   +
Sbjct: 63  GATDRRYQKSRIMKGANLVVGTPGRLLDFIGDQTISLGKCQYLILDEADRMLDMGFEPEI 242

Query: 258 QIMEDIILTLPKN-RQILLYSATFPLSVQKFMNSHLQKPYEINL-MEELTLKGVTQYYAY 315
           + + D     PK  RQ L++SATF   +Q+     L     I + +       VTQ +  
Sbjct: 243 RKLVDTHGMPPKTQRQTLMFSATFKEDIQRLAGDFLNDYLFITVGIVGGACSDVTQTFLE 422

Query: 316 VTERQKVHCLNTLFSRLQINQSIIFCNS 343
           V   QK   L  + + +   +S+  C S
Sbjct: 423 VDRLQKRDHLCEILNEMGTAKSVGVCWS 506
>10649
          Length = 472

 Score = 55.1 bits (131), Expect = 7e-08,   Method: Compositional matrix adjust.
 Identities = 37/113 (32%), Positives = 53/113 (46%), Gaps = 4/113 (3%)
 Frame = +1

Query: 358 GYSCFYIHAKMRQEHRNRVFHDFRNGLCRN----LVCTDLFTRGIDIQAVNVVINFDFPK 413
           G S   +H  + Q  R  ++ +F    CR     L+ TDL  RG+D  AVN VI  D P 
Sbjct: 64  GMSVLVLHGGIPQLRRLDIYREF----CRKQHVILITTDLACRGLDFPAVNWVIQLDCPV 231

Query: 414 LAETYLHRIGRSGRFGHLGLAINLITYDDRFNLKSIEEQLGTEIKPIPSNIDK 466
              TY+HR GR+ RF   G A+ ++   +  ++     +    IK I  N  K
Sbjct: 232 DVNTYIHRAGRTARFECNGQALLVLLPSEEEHMVEALHRKKIPIKKISVNTKK 390
>39583
          Length = 234

 Score = 54.7 bits (130), Expect = 7e-08,   Method: Composition-based stats.
 Identities = 26/64 (40%), Positives = 35/64 (54%)
 Frame = -3

Query: 366 AKMRQEHRNRVFHDFRNGLCRNLVCTDLFTRGIDIQAVNVVINFDFPKLAETYLHRIGRS 425
           A  R   R      F+ G    L+ TDL +RG+DI+ V  VINF  P   + Y+HR+GR+
Sbjct: 193 ATCR*AQRLEALKRFKEGEIDVLLATDLASRGLDIEGVKTVINFTMPSTLKHYVHRVGRT 14

Query: 426 GRFG 429
            R G
Sbjct: 13  ARAG 2
>31220
          Length = 818

 Score = 53.5 bits (127), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 27/77 (35%), Positives = 44/77 (57%), Gaps = 10/77 (12%)
 Frame = +2

Query: 395 TRGIDIQAVNVVINFDFPKLAETYLHRIGRSGRFGHLGLAINLITYDDRFNLKSIEEQLG 454
           +RGID Q VN VINFDFP    +Y+HR GR+ R  + G  ++ ++  +    +++EE+L 
Sbjct: 164 SRGIDFQGVNNVINFDFPLDVTSYIHRAGRTARGNNTGSVLSFVSVKELPINQAVEEKLR 343

Query: 455 T----------EIKPIP 461
           +          + KP+P
Sbjct: 344 SCFGREPLLKRDTKPLP 394
>33543
          Length = 471

 Score = 47.8 bits (112), Expect = 9e-06,   Method: Composition-based stats.
 Identities = 26/68 (38%), Positives = 38/68 (55%), Gaps = 2/68 (2%)
 Frame = +3

Query: 417 TYLHRIGRSGRFGHLGLAINLITYDDRFN-LKSIEEQLGTEIKPIPSNIDKSLYVAEYHS 475
           TYLHR+GR+GRFG  GLAI  ++ +   + L S++E+    +  +P  I  S Y     S
Sbjct: 3   TYLHRVGRAGRFGTRGLAITFVSNETEADVLNSVQERFEVSVTDLPEQISVSTYTEGQ*S 182

Query: 476 E-PAEDEK 482
             P E E+
Sbjct: 183 RMPVEGEE 206
>19172
          Length = 484

 Score = 47.0 bits (110), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 23/63 (36%), Positives = 36/63 (57%)
 Frame = -1

Query: 336 QSIIFCNSSQRVELLAKKISQLGYSCFYIHAKMRQEHRNRVFHDFRNGLCRNLVCTDLFT 395
           ++IIF  + +RV+ + + IS+ G+    IH    Q+ R+ V   FRNG    LV TD+  
Sbjct: 331 KTIIFVETKKRVDEITRNISRQGWRACAIHGDKSQQERDFVLSSFRNGRHSILVATDVAA 152

Query: 396 RGI 398
           RG+
Sbjct: 151 RGL 143
>12121
          Length = 465

 Score = 45.4 bits (106), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 19/48 (39%), Positives = 30/48 (62%)
 Frame = -2

Query: 98  FEDYCLKRELLMGIFEMGWEKPSPIQEESIPIALSGRDILARAKNGTG 145
           FE+  L   ++  I    W  P+PIQ +S PIA+SG+D++  A+ G+G
Sbjct: 146 FEEANLPDYVMSQIHRNNWTSPTPIQSQSWPIAMSGKDLVGIAQTGSG 3

 Score = 37.4 bits (85), Expect = 0.013,   Method: Composition-based stats.
 Identities = 15/39 (38%), Positives = 24/39 (61%)
 Frame = -3

Query: 218 VVIATPGRILDLIKKGVAKVDHVQMIVLDEADKLLSQDF 256
           + IATPGR++D ++     +     +VLDEAD++L   F
Sbjct: 463 ICIATPGRLIDFLESNRTNLRRCTYLVLDEADRMLDMGF 347
>03381
          Length = 1206

 Score = 45.4 bits (106), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 24/69 (34%), Positives = 37/69 (53%), Gaps = 1/69 (1%)
 Frame = +3

Query: 398 IDIQAVNVVINFDFPKLAETYLHRIGRSGRFGHLGLAINLITYDDR-FNLKSIEEQLGTE 456
           +DI  +  V+N+D  +  +T+ HR+GR+GR G  G A  LIT  D+ F    +    G  
Sbjct: 3   LDIPHIRTVVNYDVARDIDTHTHRVGRTGRAGEKGSAYTLITDKDKEFAPLLVRNLEGAN 182

Query: 457 IKPIPSNID 465
             P P+ +D
Sbjct: 183 QTPPPALLD 209
>11423
          Length = 1434

 Score = 45.1 bits (105), Expect = 7e-05,   Method: Compositional matrix adjust.
 Identities = 19/51 (37%), Positives = 31/51 (60%)
 Frame = -2

Query: 404  NVVINFDFPKLAETYLHRIGRSGRFGHLGLAINLITYDDRFNLKSIEEQLG 454
              VI++D P   +TY+HR+GR+ R G  G AI+L+   + F+ K +  + G
Sbjct: 1397 KYVISYDNPPYIKTYIHRVGRTARAGRAGTAISLLEKKEFFHFKQMMREAG 1245
>06438
          Length = 989

 Score = 43.9 bits (102), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 21/43 (48%), Positives = 25/43 (58%)
 Frame = +1

Query: 393 LFTRGIDIQAVNVVINFDFPKLAETYLHRIGRSGRFGHLGLAI 435
           L  RG+D  AVN VI  D P    TY+HR GR+ RF   G A+
Sbjct: 37  LACRGLDFPAVNWVIQLDCPVDVNTYIHRAGRTARFECNGQAL 165
>34134
          Length = 271

 Score = 38.9 bits (89), Expect = 0.005,   Method: Composition-based stats.
 Identities = 18/52 (34%), Positives = 34/52 (65%), Gaps = 5/52 (9%)
 Frame = +3

Query: 127 IPIALSGRDILARAKNGTGKSGAYLIPLLERLDL-----KKDNIQAMVIVPT 173
           +PIA+SGRD +  A+ G+GK+ ++++P +  ++      + D   A+V+VPT
Sbjct: 84  VPIAMSGRDCVGIAQTGSGKTLSFILPAIVHINHQPTLERGDGPIALVLVPT 239
>33083
          Length = 1931

 Score = 37.7 bits (86), Expect = 0.011,   Method: Compositional matrix adjust.
 Identities = 13/32 (40%), Positives = 23/32 (71%)
 Frame = +1

Query: 396 RGIDIQAVNVVINFDFPKLAETYLHRIGRSGR 427
           RG+DI  V+ ++ +D P  ++ Y+HR+GR+ R
Sbjct: 1   RGLDIPQVDWIVQYDPPDESKEYIHRVGRTAR 96
>28851
          Length = 328

 Score = 32.3 bits (72), Expect = 0.45,   Method: Compositional matrix adjust.
 Identities = 16/36 (44%), Positives = 23/36 (63%)
 Frame = +1

Query: 98  FEDYCLKRELLMGIFEMGWEKPSPIQEESIPIALSG 133
           F D  + R L+ G+  M +EKP+PIQ  + P +LSG
Sbjct: 223 FSDLDIARPLMKGLSTMQFEKPTPIQAPASP-SLSG 327
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6753548|ref|NP_034110.1| C-terminal binding protein 2
[Mus musculus]
         (445 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

05955                                                                 244   e-111
02672                                                                  71   1e-12
25533                                                                  69   3e-12
12358                                                                  48   1e-05
20523                                                                  33   0.30 
>05955
          Length = 1009

 Score =  244 bits (623), Expect(2) = e-111,   Method: Compositional matrix adjust.
 Identities = 115/157 (73%), Positives = 136/157 (86%)
 Frame = -1

Query: 6   KHKVKRQRLDRICEGIRPQIMNGPLHPRPLVALLDGRDCTVEMPILKDLATVAFCDAQST 65
           + +VKR R++     IR  I NGP+HPRPLVALLDGRDC+VEMPILKD+ATVAFCDAQST
Sbjct: 847 QSQVKRNRIEAPM-SIRGPIPNGPMHPRPLVALLDGRDCSVEMPILKDVATVAFCDAQST 671

Query: 66  QEIHEKVLNEAVGAMMYHTITLTREDLEKFKALRVIVRIGSGYDNVDIKAAGELGIAVCN 125
           QEIHEKVLNEAVGA+M+HTITLT+EDL+KFK+LRVI+RIGSG+DNVD+KAAGE+GIAVCN
Sbjct: 670 QEIHEKVLNEAVGALMWHTITLTKEDLDKFKSLRVIIRIGSGFDNVDVKAAGEMGIAVCN 491

Query: 126 IPSAAVEETADSTVCHILNLYRRNTWLYQALREGTRV 162
           +P   VEE ADST+C ILNLYRR  WL   +REG ++
Sbjct: 490 VPGYGVEEVADSTLCLILNLYRRTYWLANMVREGKKL 380

 Score =  174 bits (441), Expect(2) = e-111,   Method: Compositional matrix adjust.
 Identities = 84/128 (65%), Positives = 99/128 (77%)
 Frame = -3

Query: 161 RVQSVEQIREVASGAARIRGETLGLIGFGRTGQAVAVRAKAFGFSVIFYDPYLQDGIERS 220
           ++   EQ+RE A G+ARIRG+TLG++G GR G AVAVRAK FGF+VIFYDPYL DGIE+S
Sbjct: 386 KINGPEQLREAAQGSARIRGDTLGIVGLGRVGTAVAVRAKVFGFNVIFYDPYLADGIEKS 207

Query: 221 LGVQRVYTLQDLLYQSDCVSXXXXXXXXXXXXXXDFTIKQMRQGAFLVNAARGGLVDEKA 280
           LG+ RVYTLQ+LL+QSDCVS              D+TIKQMR GAFL+N ARGGLVDE A
Sbjct: 206 LGITRVYTLQELLFQSDCVSLHCTLNEHNHHLINDYTIKQMRPGAFLINTARGGLVDEHA 27

Query: 281 LAQALKEG 288
           LA ALK+G
Sbjct: 26  LAVALKDG 3
>02672
          Length = 2522

 Score = 70.9 bits (172), Expect = 1e-12,   Method: Compositional matrix adjust.
 Identities = 32/64 (50%), Positives = 41/64 (64%)
 Frame = -2

Query: 299  ESEPFSFAQGPLKDAPNLICTPHTAWYSEQASLEMXXXXXXXXXXXXXXXXPESLRNCVN 358
            ESEPFS A  P+KD PNL+ TPH+++YSEQ+  E+                P+SLRNCVN
Sbjct: 2521 ESEPFSLASSPVKDCPNLMITPHSSFYSEQSVSELREMAAGEVRRAILGRIPDSLRNCVN 2342

Query: 359  KEFF 362
            KE+F
Sbjct: 2341 KEYF 2330
>25533
          Length = 437

 Score = 69.3 bits (168), Expect = 3e-12,   Method: Compositional matrix adjust.
 Identities = 38/121 (31%), Positives = 66/121 (54%)
 Frame = +2

Query: 178 IRGETLGLIGFGRTGQAVAVRAKAFGFSVIFYDPYLQDGIERSLGVQRVYTLQDLLYQSD 237
           + G+TL +IG GR G+ VA+R ++FG + I YDP +   +      + +  L+ +  ++D
Sbjct: 74  LNGKTLAIIGLGRIGREVALRMQSFGMTTIGYDPIIGADVAAEFDTEWL-PLEQIWQRAD 250

Query: 238 CVSXXXXXXXXXXXXXXDFTIKQMRQGAFLVNAARGGLVDEKALAQALKEGRIRGAALDV 297
            ++              D    + ++G  +VN ARGG+++E AL +AL+ G+  GA LDV
Sbjct: 251 FITVHTPLIPATTNLINDAVFAKCKKGIRVVNCARGGIIEEAALLRALESGQCGGAGLDV 430

Query: 298 H 298
            
Sbjct: 431 F 433
>12358
          Length = 598

 Score = 47.8 bits (112), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 27/61 (44%), Positives = 32/61 (52%), Gaps = 3/61 (4%)
 Frame = -2

Query: 272 RGGLVDEKALAQALKEGRIRGAALDVHESEPFSFAQGPLKDAPNLICTPH---TAWYSEQ 328
           RGG+++   LA ALK G I GA LDV E EP      PL   PN + TPH     W S  
Sbjct: 549 RGGVINHDHLAVALKTGVIGGAGLDVTEPEPLPPTH-PLVHLPNCVVTPHMGSNTWDSRN 373

Query: 329 A 329
           +
Sbjct: 372 S 370
>20523
          Length = 422

 Score = 32.7 bits (73), Expect = 0.30,   Method: Compositional matrix adjust.
 Identities = 18/51 (35%), Positives = 27/51 (52%), Gaps = 1/51 (1%)
 Frame = -1

Query: 284 ALKEGRIRGAALDVHESE-PFSFAQGPLKDAPNLICTPHTAWYSEQASLEM 333
           ALK G+  GAA DV+  E P S     L + P ++ TPH    + +A + +
Sbjct: 419 ALKSGKCAGAAFDVYAEEPPKSEVTKALINHPKVVATPHLGASTSEAQVRV 267
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6755196|ref|NP_036096.1| proteasome (prosome,
macropain) subunit, alpha type 4 [Mus musculus]
         (261 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

00789                                                                 397   e-111
02448                                                                 155   2e-38
24591                                                                 152   1e-37
14551                                                                 135   2e-32
20771                                                                 118   2e-27
04255                                                                  81   7e-22
17033                                                                  99   2e-21
19133                                                                  65   3e-11
28971                                                                  65   4e-11
11023                                                                  39   0.003
37174                                                                  34   0.070
05451                                                                  33   0.16 
06516                                                                  32   0.30 
00040                                                                  28   4.3  
>00789
          Length = 1584

 Score =  397 bits (1019), Expect = e-111,   Method: Compositional matrix adjust.
 Identities = 184/237 (77%), Positives = 209/237 (88%)
 Frame = +1

Query: 1   MSRRYDSRTTIFSPEGRLYQVEYAMEAIGHAGTCLGILANDGVLLAAERRNIHKLLDEVF 60
           M+RRYDSRTTIFSPEGRLYQVEYAMEAIGHAGTCLGILA DG++LAAERRN +KLLDEV 
Sbjct: 22  MARRYDSRTTIFSPEGRLYQVEYAMEAIGHAGTCLGILAKDGIVLAAERRNTNKLLDEVS 201

Query: 61  FSEKIYKLNEDMACSVAGITSDANVLTNELRLIAQRYLLQYQEPIPCEQLVTALCDIKQA 120
           +SEKIY+L++DMACSVAGITSDANVLTNELRLIAQRYLLQYQEPIPCEQ+V  LCDIKQA
Sbjct: 202 YSEKIYRLSDDMACSVAGITSDANVLTNELRLIAQRYLLQYQEPIPCEQVVATLCDIKQA 381

Query: 121 YTQFGGKRPFGVSLLYIGWDKHYGFQLYQSDPSGNYGGWKATCIGNNSAAAVSMLKQDYK 180
           YTQFGGKRPFGVS+LY+GWDKHYGFQLYQSDPSGNYGGWKATCIGNNSA AVS+LKQ+YK
Sbjct: 382 YTQFGGKRPFGVSILYMGWDKHYGFQLYQSDPSGNYGGWKATCIGNNSANAVSLLKQEYK 561

Query: 181 EGEMTXXXXXXXXXXXXNKTMDVSKLSAEKVEIATLTRESGKTVIRVLKQKEVEQLI 237
           E E +             KT+D++KL+ +KVE+ATLTR+ GKTV+ +L   +V+ LI
Sbjct: 562 EDESSLDEALALSIKVLGKTLDLTKLTPDKVEMATLTRKDGKTVMTILPDNQVDTLI 732
>02448
          Length = 1302

 Score =  155 bits (391), Expect = 2e-38,   Method: Compositional matrix adjust.
 Identities = 84/237 (35%), Positives = 131/237 (55%)
 Frame = +2

Query: 1   MSRRYDSRTTIFSPEGRLYQVEYAMEAIGHAGTCLGILANDGVLLAAERRNIHKLLDEVF 60
           MS RYD   T+FSP+G L+QVEYA EA+    T +G+  N+ V+L  E++ + KL +E  
Sbjct: 251 MSDRYDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGNNLVVLGVEKKAVAKLQEERT 430

Query: 61  FSEKIYKLNEDMACSVAGITSDANVLTNELRLIAQRYLLQYQEPIPCEQLVTALCDIKQA 120
              KI  L+E +A + AG+T+DA +L N  R+  Q + L  ++P+  E +   +  +KQ 
Sbjct: 431 V-RKIALLDEHVALAFAGLTADARILINRARIECQSHKLTVEDPVTVEYITRHIAQLKQK 607

Query: 121 YTQFGGKRPFGVSLLYIGWDKHYGFQLYQSDPSGNYGGWKATCIGNNSAAAVSMLKQDYK 180
           YTQ  G+RPFG+S L IG+D      LYQ+DPSG Y  WKA  IG N+      L++ Y 
Sbjct: 608 YTQSNGRRPFGLSSLIIGFDYDGSPHLYQTDPSGTYHEWKANTIGRNAKTVREFLEKHYT 787

Query: 181 EGEMTXXXXXXXXXXXXNKTMDVSKLSAEKVEIATLTRESGKTVIRVLKQKEVEQLI 237
             +                 ++V +  A+ +E+A + R      +++L+  E+E+ I
Sbjct: 788 --DEVAASDKETIKLALKALLEVVQSGAKNMEVAVMRRGQA---LQMLESDEIEKYI 943
>24591
          Length = 1801

 Score =  152 bits (385), Expect = 1e-37,   Method: Compositional matrix adjust.
 Identities = 83/237 (35%), Positives = 131/237 (55%)
 Frame = +1

Query: 1   MSRRYDSRTTIFSPEGRLYQVEYAMEAIGHAGTCLGILANDGVLLAAERRNIHKLLDEVF 60
           MS RYD   T+FSP+G L+QVEYA EA+    T +G+  ++ V+L  E++ + KL +E  
Sbjct: 28  MSDRYDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGDNLVVLGVEKKAVAKLQEERT 207

Query: 61  FSEKIYKLNEDMACSVAGITSDANVLTNELRLIAQRYLLQYQEPIPCEQLVTALCDIKQA 120
              KI  L+E +A + AG+T+DA +L N  R+  Q + L  ++P+  E +   +  +KQ 
Sbjct: 208 V-RKIALLDEHVALAFAGLTADARILINRARIECQSHKLTVEDPVTVEYITRHIAQLKQK 384

Query: 121 YTQFGGKRPFGVSLLYIGWDKHYGFQLYQSDPSGNYGGWKATCIGNNSAAAVSMLKQDYK 180
           YTQ  G+RPFG+S L IG+D      LYQ+DPSG Y  WKA  IG N+      L++ Y 
Sbjct: 385 YTQSNGRRPFGLSSLIIGFDYDGTPHLYQTDPSGTYHEWKANTIGRNAKTVREFLEKHYT 564

Query: 181 EGEMTXXXXXXXXXXXXNKTMDVSKLSAEKVEIATLTRESGKTVIRVLKQKEVEQLI 237
             +                 ++V +  A+ +E+A + R      +++L+  E+E+ I
Sbjct: 565 --DEVAASDKETIKLALKALLEVVQSGAKNMEVAVMRRGQA---LQMLESDEIEKYI 720
>14551
          Length = 1344

 Score =  135 bits (340), Expect = 2e-32,   Method: Compositional matrix adjust.
 Identities = 73/182 (40%), Positives = 102/182 (56%), Gaps = 1/182 (0%)
 Frame = +3

Query: 1   MSRRYDSRTTIFSPEGRLYQVEYAMEAIGHAGTCLGILANDGVLLAAERRNIHKLLDEVF 60
           M+ RY    T FSP G+L Q+EYA+ A+G     +GI A +GV+LA E++      DE  
Sbjct: 141 MTERYSFSLTTFSPSGKLVQIEYALAAVGAGAPSVGIKATNGVVLATEKKQKSVXYDEHS 320

Query: 61  FSEKIYKLNEDMACSVAGITSDANVLTNELRLIAQRYLLQYQEPIPCEQLVTALCDIKQA 120
            + K+  + +++    +G+  D  VL    R +A++Y   Y E IP  QLV  +  + Q 
Sbjct: 321 IN-KVETITKNIGIVYSGMGPDYRVLCRRARKLAEQYKRVYNEQIPTAQLVQRVAAVMQE 497

Query: 121 YTQFGGKRPFGVSLLYIGWDKHYGFQ-LYQSDPSGNYGGWKATCIGNNSAAAVSMLKQDY 179
           +TQ GG RPFGVSLL  GWD+      LYQ DPSG Y  WKAT +G N     + L++ Y
Sbjct: 498 FTQSGGVRPFGVSLLMAGWDEDDKKPFLYQCDPSGAYFAWKATAMGKNHINGKTFLEKRY 677

Query: 180 KE 181
            E
Sbjct: 678 SE 683
>20771
          Length = 674

 Score =  118 bits (296), Expect = 2e-27,   Method: Compositional matrix adjust.
 Identities = 65/182 (35%), Positives = 103/182 (56%), Gaps = 5/182 (2%)
 Frame = +2

Query: 5   YDSRTTIFSPEGRLYQVEYAMEAIGHAGTCLGILANDGVLLAAERRNIHKLLDEVFFSEK 64
           YD     FSPEGRL+QVEYA+EAI    T +GI  N+GV+LA E+R    L++     EK
Sbjct: 101 YDRGVNTFSPEGRLFQVEYAIEAIKLGSTAIGIQTNEGVVLAVEKRVTSSLIEPTSI-EK 277

Query: 65  IYKLNEDMACSVAGITSDANVLTNELRLIAQRYLLQYQEPIPCEQLVTALCDIKQAY--- 121
           I ++++ + C+++G+ +D+  L +  R+ AQ +   Y E +  E +  A+ ++  A+   
Sbjct: 278 IMEVDKHIGCAMSGLIADSRTLIDRARVEAQNHWFTYNENMSVESVTQAVSNLALAFGDD 457

Query: 122 --TQFGGKRPFGVSLLYIGWDKHYGFQLYQSDPSGNYGGWKATCIGNNSAAAVSMLKQDY 179
                   RPFGV+LL  G D + G +L+  DPSG +  + A  IG+ S  A   L++ Y
Sbjct: 458 DPDPGAMSRPFGVALLIAGVDSN-GPRLFHMDPSGTFIQYDAKAIGSGSEGAQQALQEQY 634

Query: 180 KE 181
            +
Sbjct: 635 HK 640
>04255
          Length = 1758

 Score = 80.9 bits (198), Expect(2) = 7e-22,   Method: Compositional matrix adjust.
 Identities = 48/181 (26%), Positives = 87/181 (48%)
 Frame = -2

Query: 54   KLLDEVFFSEKIYKLNEDMACSVAGITSDANVLTNELRLIAQRYLLQYQEPIPCEQLVTA 113
            KLLD    +  +Y L E + C + G+ +D+       R  A ++   Y   IP + L   
Sbjct: 1457 KLLDPTTVTH-LYSLTERIGCVMTGMIADSQSQVQRARYEAAKWKYTYGYDIPVDMLCKR 1281

Query: 114  LCDIKQAYTQFGGKRPFGVSLLYIGWDKHYGFQLYQSDPSGNYGGWKATCIGNNSAAAVS 173
            + +I Q YTQ    RP G  ++ IG+D   G ++Y++DP+G Y G+KAT  G+    A  
Sbjct: 1280 IANINQVYTQSAEMRPLGCCMILIGYDDEKGPEVYKTDPAGYYCGFKATSAGSKQLEANG 1101

Query: 174  MLKQDYKEGEMTXXXXXXXXXXXXNKTMDVSKLSAEKVEIATLTRESGKTVIRVLKQKEV 233
             L++  K+ +                T+  +   A +VE+  +T+++     R+L + ++
Sbjct: 1100 FLEKKIKKKQDFTYNEAAEIAITCLSTVLSADFKASEVEVGIVTKDNPN--FRILTEADI 927

Query: 234  E 234
            +
Sbjct: 926  D 924

 Score = 40.0 bits (92), Expect(2) = 7e-22,   Method: Compositional matrix adjust.
 Identities = 17/40 (42%), Positives = 25/40 (62%), Gaps = 1/40 (2%)
 Frame = -3

Query: 12   FSPEGRLYQVEYAMEAIGHAG-TCLGILANDGVLLAAERR 50
             SPEGRLYQVEYA +AI   G T + +   D  ++  +++
Sbjct: 1585 LSPEGRLYQVEYAFKAINQGGLTSVAVRGKDSAVIVTQKK 1466
>17033
          Length = 2217

 Score = 98.6 bits (244), Expect = 2e-21,   Method: Compositional matrix adjust.
 Identities = 52/167 (31%), Positives = 89/167 (53%)
 Frame = -3

Query: 5    YDSRTTIFSPEGRLYQVEYAMEAIGHAGTCLGILANDGVLLAAERRNIHKLLDEVFFSEK 64
            YD   + FSP+GR++QVEYA +A+ ++GT +GI   DGV++  E+    KL ++   +++
Sbjct: 2149 YDLSASHFSPDGRVFQVEYAQKAVENSGTAIGIRGKDGVVMGVEKLVTSKLYEQ-GANKR 1973

Query: 65   IYKLNEDMACSVAGITSDANVLTNELRLIAQRYLLQYQEPIPCEQLVTALCDIKQAYTQF 124
            ++ ++  +  +VAG+ +DA  L    +  +  Y   Y  P+P + L   +     AYT  
Sbjct: 1972 LFNIDRHIGGAVAGLLADARQLMERAKEESSNYRFNYGSPVPLKYLTDRVAGYVHAYTLH 1793

Query: 125  GGKRPFGVSLLYIGWDKHYGFQLYQSDPSGNYGGWKATCIGNNSAAA 171
               RPFG S++   +D   G Q++  +PSG   G+    IG     A
Sbjct: 1792 SAVRPFGTSMIVASYDA-VGPQMFLVEPSGVSWGYYGCAIGKAKQTA 1655
>19133
          Length = 692

 Score = 64.7 bits (156), Expect = 3e-11,   Method: Compositional matrix adjust.
 Identities = 38/99 (38%), Positives = 57/99 (57%)
 Frame = +1

Query: 79  ITSDANVLTNELRLIAQRYLLQYQEPIPCEQLVTALCDIKQAYTQFGGKRPFGVSLLYIG 138
           +T+DA +L N ++         YQ+P+P  +LV+A+ +  Q  T   G+RPFGV LL  G
Sbjct: 1   LTADARLLCNFMQTECLDSRWAYQQPLPVSRLVSAIGNKLQIPTHRYGRRPFGVGLLIAG 180

Query: 139 WDKHYGFQLYQSDPSGNYGGWKATCIGNNSAAAVSMLKQ 177
           +D   G  +YQ+ PS NY   KA  IG  S +A + L++
Sbjct: 181 YDWS-GPHIYQTCPSANYYDCKAMAIGARSQSARTYLER 294
>28971
          Length = 437

 Score = 64.7 bits (156), Expect = 4e-11,   Method: Compositional matrix adjust.
 Identities = 33/57 (57%), Positives = 37/57 (64%)
 Frame = +1

Query: 119 QAYTQFGGKRPFGVSLLYIGWDKHYGFQLYQSDPSGNYGGWKATCIGNNSAAAVSML 175
           Q YTQ GG RPFGVSLL  GWD    + LYQSDPSG Y  WKAT +G N+    + L
Sbjct: 4   QEYTQSGGVRPFGVSLLICGWDNERPY-LYQSDPSGAYFAWKATAMGKNAVNGKNFL 171
>11023
          Length = 1057

 Score = 38.5 bits (88), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 16/44 (36%), Positives = 28/44 (63%)
 Frame = -2

Query: 134 LLYIGWDKHYGFQLYQSDPSGNYGGWKATCIGNNSAAAVSMLKQ 177
           ++ IG+D   G ++Y++DP+G Y G+KAT  G+    A   L++
Sbjct: 996 MILIGYDDEKGPEVYKTDPAGYYCGFKATSAGSKQLEANGFLEK 865
>37174
          Length = 146

 Score = 33.9 bits (76), Expect = 0.070,   Method: Compositional matrix adjust.
 Identities = 14/32 (43%), Positives = 21/32 (65%)
 Frame = +1

Query: 14 PEGRLYQVEYAMEAIGHAGTCLGILANDGVLL 45
          P  +L Q+EYA+ A+G     +GI A +GV+L
Sbjct: 43 PTAQLVQIEYALAAVGAGAPVVGIKATNGVVL 138
>05451
          Length = 769

 Score = 32.7 bits (73), Expect = 0.16,   Method: Compositional matrix adjust.
 Identities = 20/63 (31%), Positives = 30/63 (47%), Gaps = 2/63 (3%)
 Frame = +2

Query: 57  DEVFFSEKIYKLNEDMACSVAGITSDANVLTNELRLIAQRYLL--QYQEPIPCEQLVTAL 114
           DEVF+  +I KL ++  C V  I    N +TNE R +     +  +Y +    E    A 
Sbjct: 2   DEVFYRAEIVKLLDEGKCEVHFIDFGNNAITNEFRQLPDELAIAPRYSKHCELESATIAK 181

Query: 115 CDI 117
           CD+
Sbjct: 182 CDV 190
>06516
          Length = 835

 Score = 31.6 bits (70), Expect = 0.30,   Method: Compositional matrix adjust.
 Identities = 27/124 (21%), Positives = 55/124 (44%), Gaps = 1/124 (0%)
 Frame = +1

Query: 33  TCLGILANDGVLLAAERRNIHKLLDEVFFSEKIYKLNEDMACSVAGITSDANVLTNELRL 92
           T + +   DGV++ A+ R           ++K+ K+ + + C  +G  +D   + + ++ 
Sbjct: 127 TIMAVEYEDGVVIGADSRTTTGAYIANRVTDKLTKVTDRIYCCRSGSAADTQAIADIVKY 306

Query: 93  IAQRYLLQY-QEPIPCEQLVTALCDIKQAYTQFGGKRPFGVSLLYIGWDKHYGFQLYQSD 151
               Y ++  +EP    Q+ TA    ++    +  +      ++  GWDK  G Q+Y S 
Sbjct: 307 HLDFYRMEMGEEP----QVQTAANVFRELC--YDNRDSLTAGIIVAGWDKRTGGQVY-SV 465

Query: 152 PSGN 155
           P G 
Sbjct: 466 PIGG 477
>00040
          Length = 521

 Score = 27.7 bits (60), Expect = 4.3,   Method: Compositional matrix adjust.
 Identities = 13/42 (30%), Positives = 21/42 (50%)
 Frame = +1

Query: 74  CSVAGITSDANVLTNELRLIAQRYLLQYQEPIPCEQLVTALC 115
           CS+  +  D N+    + L+A  +     E IPC ++V  LC
Sbjct: 301 CSLDTMNVDFNIFNGIMTLVALSFSRFSSEEIPCLEIVLILC 426
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|23956078|ref|NP_038881.1| ATP-binding cassette,
sub-family F (GCN20), member 2 [Mus musculus]
         (628 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

38795                                                                 392   e-109
33929                                                                 119   4e-27
03538                                                                 117   1e-26
22801                                                                 101   1e-21
01623                                                                  49   8e-06
05764                                                                  44   2e-04
02301                                                                  44   3e-04
20290                                                                  37   0.029
12308                                                                  35   0.064
30281                                                                  32   0.72 
22529                                                                  32   0.86 
01142                                                                  32   0.86 
18248                                                                  32   1.1  
19618                                                                  31   1.6  
27295                                                                  30   2.4  
29130                                                                  30   3.7  
06358                                                                  28   8.1  
>38795
          Length = 792

 Score =  392 bits (1007), Expect = e-109,   Method: Compositional matrix adjust.
 Identities = 188/251 (74%), Positives = 220/251 (87%)
 Frame = +1

Query: 192 EKLMELYERLEELDADKAEMRASRILHGLGFTPAMQRKKLKDFSGGWRMRVALARALFIR 251
           ++L+ +Y+RL+ELD+ KA  +A  ILHGLGF+  MQ  K+K+FSGGWRMR+ LARAL++R
Sbjct: 7   DRLLAVYDRLDELDSTKALAKAGFILHGLGFSKDMQHTKVKNFSGGWRMRIGLARALYLR 186

Query: 252 PFMLLLDEPTNHLDLDACVWLEEELKTFKRILVLVSHSQDFLNGVCTNIIHMHNKKLKYY 311
           P +LLLDEPTNHLDL+ACVWLEEELK + RILV++SHSQDFLNGVC +IIHM+ KKL+YY
Sbjct: 187 PSLLLLDEPTNHLDLNACVWLEEELKNYPRILVIISHSQDFLNGVCNSIIHMNQKKLQYY 366

Query: 312 TGNYDQYVKTRLELEENQMKRFHWEQDQIAHMKNYIARFGHGSAKLARQAQSKEKTLQKM 371
            GNYD YV+TRLEL ENQ KR+ WEQDQI+HMKNYIARFGHGSAKLARQAQSKEKTL+KM
Sbjct: 367 GGNYDSYVQTRLELLENQAKRYKWEQDQISHMKNYIARFGHGSAKLARQAQSKEKTLKKM 546

Query: 372 MASGLTERVVSDKTLSFYFPPCGKIPPPVIMVQNVSFKYTKDGPCIYNNLEFGIDLDTRV 431
           +  GLTE+V SDKTLSFYFP CG IPPPVIMVQ+VSF+Y +  P IY NL+FGIDLDTRV
Sbjct: 547 VDGGLTEKVTSDKTLSFYFPSCGTIPPPVIMVQHVSFRYNETKPYIYQNLDFGIDLDTRV 726

Query: 432 ALVGPNGAGKS 442
           ALVGPNGAGKS
Sbjct: 727 ALVGPNGAGKS 759

 Score = 42.4 bits (98), Expect = 6e-04,   Method: Compositional matrix adjust.
 Identities = 26/98 (26%), Positives = 49/98 (50%)
 Frame = +1

Query: 509 GLTGKQQVSPIRNLSDGQKCRVCLAWLAWQNPHMLFLDEPTNHLDIETIDALADAINEFE 568
           G +   Q + ++N S G + R+ LA   +  P +L LDEPTNHLD+     L + +  + 
Sbjct: 94  GFSKDMQHTKVKNFSGGWRMRIGLARALYLRPSLLLLDEPTNHLDLNACVWLEEELKNYP 273

Query: 569 GGMMLVSHDFRLIQQVAQEIWVCEKQTITKWPGDILAY 606
             ++++SH    +  V   I    ++ +  + G+  +Y
Sbjct: 274 RILVIISHSQDFLNGVCNSIIHMNQKKLQYYGGNYDSY 387
>33929
          Length = 408

 Score =  119 bits (298), Expect = 4e-27,   Method: Compositional matrix adjust.
 Identities = 59/109 (54%), Positives = 82/109 (75%), Gaps = 1/109 (0%)
 Frame = +1

Query: 51  ETTGDG-EVDLLTKELEDFEMKKAAARAVTGVLASHPNSTDVHIINLSLTFHGQELLSDT 109
           ET G G  ++++TK+L++ ++  A  R+VTGVLASH +S D+HI N+S+ FHG ELL D+
Sbjct: 82  ETNGTGASIEVVTKQLDEMDIA-AQHRSVTGVLASHGDSRDLHIHNMSILFHGAELLMDS 258

Query: 110 KLELNSGRRYGLIGLNGIGKSMLLSAIGKREVPIPEHIDIYHLTREMPP 158
           KLE+N G+RYGLIGLNG GKS LL+A+  +EV IP+HIDI+    +  P
Sbjct: 259 KLEMNVGKRYGLIGLNGCGKSSLLAALANKEVAIPDHIDIFCFGEKCHP 405
>03538
          Length = 1974

 Score =  117 bits (293), Expect = 1e-26,   Method: Compositional matrix adjust.
 Identities = 66/177 (37%), Positives = 90/177 (50%)
 Frame = -1

Query: 438  GAGKSXXXXXXXXXXXXXDGMIRKHSHVKIGRYXXXXXXXXXXXXSPLEYMMKCYPXXXX 497
            G GKS              G  R +  +++G+Y            SP+EY+ + +     
Sbjct: 1971 GVGKSTLLKLLMGDLQPSQGEKRMNHRLRVGKYDQHSADQLNLDESPVEYLKRLFDLQYQ 1792

Query: 498  XXXXXXXXGRYGLTGKQQVSPIRNLSDGQKCRVCLAWLAWQNPHMLFLDEPTNHLDIETI 557
                    GR GL         R+LS GQ+ RV LA L+ + P +L LDEPTN+LDIE+I
Sbjct: 1791 DARKML--GRVGLASHAHTILNRDLSGGQRARVALAELSCRAPDVLVLDEPTNNLDIESI 1618

Query: 558  DALADAINEFEGGMMLVSHDFRLIQQVAQEIWVCEKQTITKWPGDILAYKEHLKSKL 614
            DALADAI  F GG+++VSHD RLI+    ++WV E  TI +  GD   Y+  L   L
Sbjct: 1617 DALADAIKNFTGGVIIVSHDERLIRDTNCQLWVVEDNTINEVDGDFDDYRRELLEAL 1447

 Score = 61.2 bits (147), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 34/112 (30%), Positives = 58/112 (51%)
 Frame = -1

Query: 213  ASRILHGLGFTPAMQRKKLKDFSGGWRMRVALARALFIRPFMLLLDEPTNHLDLDACVWL 272
            A ++L  +G          +D SGG R RVALA      P +L+LDEPTN+LD+++   L
Sbjct: 1788 ARKMLGRVGLASHAHTILNRDLSGGQRARVALAELSCRAPDVLVLDEPTNNLDIESIDAL 1609

Query: 273  EEELKTFKRILVLVSHSQDFLNGVCTNIIHMHNKKLKYYTGNYDQYVKTRLE 324
             + +K F   +++VSH +  +      +  + +  +    G++D Y +  LE
Sbjct: 1608 ADAIKNFTGGVIIVSHDERLIRDTNCQLWVVEDNTINEVDGDFDDYRRELLE 1453
>22801
          Length = 753

 Score =  101 bits (251), Expect = 1e-21,   Method: Compositional matrix adjust.
 Identities = 50/95 (52%), Positives = 65/95 (68%)
 Frame = -1

Query: 520 RNLSDGQKCRVCLAWLAWQNPHMLFLDEPTNHLDIETIDALADAINEFEGGMMLVSHDFR 579
           R+LS GQ+ RV LA L+ + P +L LDEPTN+LDIE+IDALADAI  F GG+++VSHD R
Sbjct: 738 RDLSGGQRARVALAELSCRAPDVLVLDEPTNNLDIESIDALADAIKNFTGGVIIVSHDER 559

Query: 580 LIQQVAQEIWVCEKQTITKWPGDILAYKEHLKSKL 614
           LI+    ++WV E  TI +  GD   Y+  L   L
Sbjct: 558 LIRDTNCQLWVVEDNTINEVDGDFDDYRRELLEAL 454

 Score = 60.8 bits (146), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 31/93 (33%), Positives = 52/93 (55%)
 Frame = -1

Query: 232 KDFSGGWRMRVALARALFIRPFMLLLDEPTNHLDLDACVWLEEELKTFKRILVLVSHSQD 291
           +D SGG R RVALA      P +L+LDEPTN+LD+++   L + +K F   +++VSH + 
Sbjct: 738 RDLSGGQRARVALAELSCRAPDVLVLDEPTNNLDIESIDALADAIKNFTGGVIIVSHDER 559

Query: 292 FLNGVCTNIIHMHNKKLKYYTGNYDQYVKTRLE 324
            +      +  + +  +    G++D Y +  LE
Sbjct: 558 LIRDTNCQLWVVEDNTINEVDGDFDDYRRELLE 460
>01623
          Length = 1414

 Score = 48.5 bits (114), Expect = 8e-06,   Method: Compositional matrix adjust.
 Identities = 30/100 (30%), Positives = 53/100 (53%), Gaps = 3/100 (3%)
 Frame = +3

Query: 522 LSDGQKCRVCLAWLAWQNPHMLFLDEPTNHLDIETIDALADAINEFEGGMMLVSHDFRLI 581
           LS GQ+ R+ +A    +NP +L LDE T+ LD E+   + DA+ +  GG  +++   RL 
Sbjct: 453 LSGGQRQRIAIARAILKNPEILLLDEATSALDAESEYLVQDALEKLMGGRTVITIAHRLS 632

Query: 582 Q-QVAQEIWVCEKQTITKWPG--DILAYKEHLKSKLVDEE 618
             + A +I V     + +     D++A  + +  KLV+ +
Sbjct: 633 TIKTANQIAVLTDGVVAEMGSYQDLIAINDGIFRKLVERQ 752

 Score = 43.5 bits (101), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 21/57 (36%), Positives = 36/57 (63%), Gaps = 2/57 (3%)
 Frame = +3

Query: 234 FSGGWRMRVALARALFIRPFMLLLDEPTNHLDLDACVWLEEELKTF--KRILVLVSH 288
            SGG R R+A+ARA+   P +LLLDE T+ LD ++   +++ L+     R ++ ++H
Sbjct: 453 LSGGQRQRIAIARAILKNPEILLLDEATSALDAESEYLVQDALEKLMGGRTVITIAH 623
>05764
          Length = 1395

 Score = 43.5 bits (101), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 23/61 (37%), Positives = 36/61 (59%), Gaps = 2/61 (3%)
 Frame = -2

Query: 230 KLKDFSGGWRMRVALARALFIRPFMLLLDEPTNHLDLDACVWLEEELKTFK--RILVLVS 287
           K    SGG + RVA+ARAL   P +LLLDE T+ LD ++   ++  L   +  R  ++++
Sbjct: 725 KGTQLSGGQKQRVAIARALVRNPIILLLDEATSALDTESEKLVQAALDNAREGRTCIVIA 546

Query: 288 H 288
           H
Sbjct: 545 H 543

 Score = 41.6 bits (96), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 28/77 (36%), Positives = 41/77 (53%), Gaps = 2/77 (2%)
 Frame = -2

Query: 522 LSDGQKCRVCLAWLAWQNPHMLFLDEPTNHLDIETIDALADAINEFEGG--MMLVSHDFR 579
           LS GQK RV +A    +NP +L LDE T+ LD E+   +  A++    G   ++++H   
Sbjct: 713 LSGGQKQRVAIARALVRNPIILLLDEATSALDTESEKLVQAALDNAREGRTCIVIAHRLS 534

Query: 580 LIQQVAQEIWVCEKQTI 596
            IQ  A  I+V E   I
Sbjct: 533 TIQN-ADVIFVMENGQI 486

 Score = 29.6 bits (65), Expect = 3.5,   Method: Compositional matrix adjust.
 Identities = 11/31 (35%), Positives = 22/31 (70%)
 Frame = -2

Query: 104  ELLSDTKLELNSGRRYGLIGLNGIGKSMLLS 134
            ++L    LE+++G+   L+G++G GKS ++S
Sbjct: 1085 QVLKGISLEISAGQTAALVGISGCGKSTIIS 993
>02301
          Length = 1098

 Score = 43.5 bits (101), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 22/57 (38%), Positives = 36/57 (63%), Gaps = 2/57 (3%)
 Frame = -2

Query: 234 FSGGWRMRVALARALFIRPFMLLLDEPTNHLDLDACVWLEEELK--TFKRILVLVSH 288
            SGG + R+A+ARAL  +P +LLLDE T+ LD  +   ++  +   T  R +V+++H
Sbjct: 686 LSGGQKQRLAIARALVRQPAILLLDEATSALDTQSESLVQSAINECTRGRTVVIIAH 516

 Score = 40.8 bits (94), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 24/79 (30%), Positives = 43/79 (54%), Gaps = 2/79 (2%)
 Frame = -2

Query: 522 LSDGQKCRVCLAWLAWQNPHMLFLDEPTNHLDIETIDALADAINEFEGG--MMLVSHDFR 579
           LS GQK R+ +A    + P +L LDE T+ LD ++   +  AINE   G  +++++H   
Sbjct: 686 LSGGQKQRLAIARALVRQPAILLLDEATSALDTQSESLVQSAINECTRGRTVVIIAHRLT 507

Query: 580 LIQQVAQEIWVCEKQTITK 598
            +++ A  + V  K  + +
Sbjct: 506 TVEK-ADRVLVINKGRVVE 453
>20290
          Length = 1550

 Score = 36.6 bits (83), Expect = 0.029,   Method: Compositional matrix adjust.
 Identities = 26/94 (27%), Positives = 42/94 (44%), Gaps = 8/94 (8%)
 Frame = +3

Query: 519  IRNLSDGQKCRVCLAWLAWQNPHMLFLDEPTNHLDIETIDALADAINEF----EGGMMLV 574
            ++NLS G+  RV L     +   +  +DEP+ +LD E     A  I  +    +    +V
Sbjct: 1038 VQNLSGGELQRVALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRYILHAKKTGFVV 1217

Query: 575  SHDFRLIQQVAQEIWVCEKQ----TITKWPGDIL 604
             HDF +   +A  + V E Q    T+   P  +L
Sbjct: 1218 EHDFIMATYLADRVIVIEGQPSVKTVAYSPQSLL 1319
>12308
          Length = 698

 Score = 35.4 bits (80), Expect = 0.064,   Method: Compositional matrix adjust.
 Identities = 43/187 (22%), Positives = 76/187 (40%), Gaps = 10/187 (5%)
 Frame = -3

Query: 92  HIINLS----LTFHGQELLSDTKLELNSGRRYGLIGLNGIGKSMLLSAIGK------REV 141
           H+I       +T +G  L+ +   E+ +G    + G NG GKS L   +G+        +
Sbjct: 543 HVIKFDKVPLVTPNGDVLIPELSFEVKAGMNVLVCGPNGCGKSSLFRILGELWPLFGGSL 364

Query: 142 PIPEHIDIYHLTREMPPSEKTPLQCVMEVDTXXXXXXXXXXXXXXXXXXCEKLMELYERL 201
             PE   ++++          P +  M V T                   E+ +    R 
Sbjct: 363 TKPEKGKLFYI----------PQRPYMTVGTLRDQVTYPDSH--------EEQLRKGTRD 238

Query: 202 EELDADKAEMRASRILHGLGFTPAMQRKKLKDFSGGWRMRVALARALFIRPFMLLLDEPT 261
           EEL     +++   +L   G   A+Q   +   SGG + R+A+AR  + +P   +LDE T
Sbjct: 237 EELADILGKVQLDYVLQREGGWDAVQ-DWMDVLSGGEKQRIAMARLFYHKPQFAILDECT 61

Query: 262 NHLDLDA 268
           + + +D 
Sbjct: 60  SAVSVDV 40
>30281
          Length = 821

 Score = 32.0 bits (71), Expect = 0.72,   Method: Compositional matrix adjust.
 Identities = 30/114 (26%), Positives = 55/114 (48%), Gaps = 17/114 (14%)
 Frame = -2

Query: 233 DFSGGWRMRVALARALFIRPFMLLLDEPTNHLDLDACVWLEEELKTFKRIL-----VLVS 287
           + SGG + RV++ARA++    + LLD+P + +D      +  ++     +L     VLV+
Sbjct: 637 NLSGGQKQRVSVARAVYSDSDVYLLDDPLSAVDSHVGKAIFSKVIGPNGLLRGTTRVLVT 458

Query: 288 HSQDFLNGVCTNIIHMHNK--------KLKYYTGNYDQYVKTRL----ELEENQ 329
           H   +L  V   ++ M  K        +L  + G +  ++KT L    E+EE +
Sbjct: 457 HGVHWLPMVDEILVLMDGKISERGSYEELVSHDGPFAHFLKTYLTEVFEVEEQE 296
>22529
          Length = 312

 Score = 32.0 bits (71), Expect = 0.86,   Method: Compositional matrix adjust.
 Identities = 15/47 (31%), Positives = 29/47 (61%), Gaps = 2/47 (4%)
 Frame = +3

Query: 538 QNPHMLFLDEPTNHLDIETIDALADAINEFEGG--MMLVSHDFRLIQ 582
           +NP +L LDE T+ LD+E+   + DA+++   G   ++++H    I+
Sbjct: 9   RNPKILLLDEATSALDMESEKTVQDALDKARQGRTTIVIAHRLSTIK 149
>01142
          Length = 729

 Score = 32.0 bits (71), Expect = 0.86,   Method: Compositional matrix adjust.
 Identities = 19/40 (47%), Positives = 25/40 (62%)
 Frame = -1

Query: 521 NLSDGQKCRVCLAWLAWQNPHMLFLDEPTNHLDIETIDAL 560
           +LS GQ+  VCLA    +   +L LDE T  +D+ET DAL
Sbjct: 489 SLSVGQRQLVCLARTLLRRSRVLILDEATAAVDMET-DAL 373

 Score = 30.4 bits (67), Expect = 2.3,   Method: Compositional matrix adjust.
 Identities = 16/45 (35%), Positives = 25/45 (55%)
 Frame = -1

Query: 234 FSGGWRMRVALARALFIRPFMLLLDEPTNHLDLDACVWLEEELKT 278
            S G R  V LAR L  R  +L+LDE T  +D++    ++  L++
Sbjct: 486 LSVGQRQLVCLARTLLRRSRVLILDEATAAVDMETDALIQNTLRS 352
>18248
          Length = 466

 Score = 31.6 bits (70), Expect = 1.1,   Method: Composition-based stats.
 Identities = 17/37 (45%), Positives = 22/37 (59%)
 Frame = +1

Query: 229 KKLKDFSGGWRMRVALARALFIRPFMLLLDEPTNHLD 265
           KK K+ SGG   RVAL   L     + L+DEP+ +LD
Sbjct: 355 KKYKNLSGGELQRVALTLCLGKPADVYLIDEPSAYLD 465
>19618
          Length = 974

 Score = 30.8 bits (68), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 13/35 (37%), Positives = 22/35 (62%)
 Frame = +2

Query: 234 FSGGWRMRVALARALFIRPFMLLLDEPTNHLDLDA 268
            SGG + R+A+AR  + +P   +LDE T+ + +D 
Sbjct: 197 LSGGEKQRIAMARLFYHKPQFAILDECTSAVSVDV 301

 Score = 30.0 bits (66), Expect = 2.8,   Method: Compositional matrix adjust.
 Identities = 17/58 (29%), Positives = 27/58 (46%)
 Frame = +2

Query: 519 IRNLSDGQKCRVCLAWLAWQNPHMLFLDEPTNHLDIETIDALADAINEFEGGMMLVSH 576
           I  LS G+K R+ +A L +  P    LDE T+ + ++    +     E    +  VSH
Sbjct: 188 IDVLSGGEKQRIAMARLFYHKPQFAILDECTSAVSVDVEGKMYSYCREVGITLFTVSH 361
>27295
          Length = 384

 Score = 30.4 bits (67), Expect = 2.4,   Method: Composition-based stats.
 Identities = 18/49 (36%), Positives = 27/49 (55%), Gaps = 1/49 (2%)
 Frame = +3

Query: 506 GRYGLTGKQQVSPIRNLSDGQK-CRVCLAWLAWQNPHMLFLDEPTNHLD 553
           G+   +G Q VSP RN   G +      A L+  +P + +LDEPT+ +D
Sbjct: 237 GKGSRSGVQAVSPGRNTVWGDRNVNSASASLSLVDPRL*YLDEPTSGMD 383
>29130
          Length = 436

 Score = 29.6 bits (65), Expect = 3.7,   Method: Composition-based stats.
 Identities = 13/32 (40%), Positives = 19/32 (59%)
 Frame = +3

Query: 105 LLSDTKLELNSGRRYGLIGLNGIGKSMLLSAI 136
           +L D   E+N G + G++G  G GKS L  A+
Sbjct: 39  VLRDLTYEINPGEKVGIVGRTGAGKSSLTLAL 134
>06358
          Length = 1517

 Score = 28.5 bits (62), Expect = 8.1,   Method: Compositional matrix adjust.
 Identities = 13/29 (44%), Positives = 19/29 (65%), Gaps = 1/29 (3%)
 Frame = -1

Query: 78  VTGVLASHPNSTDVHIIN-LSLTFHGQEL 105
           ++ VL  HP  TD H+   LS+TF G++L
Sbjct: 806 ISQVLRHHPQQTDTHVTQLLSVTFKGRQL 720
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|225543576|ref|NP_032213.2| gene trap locus 3 [Mus
musculus]
         (193 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

05616                                                                 385   e-108
07552                                                                 278   1e-75
>05616
          Length = 1678

 Score =  385 bits (990), Expect = e-108,   Method: Compositional matrix adjust.
 Identities = 185/188 (98%), Positives = 187/188 (99%)
 Frame = -1

Query: 1    MFKNTFQSGFLSILYSIGSKPLQIWDKKVRNGHIKRITDNDIQSLVLEIEGTNVSTTYIT 60
            MFKNTFQSGFLSILYSIGSKPLQIWDKKVRNGHIKRITDNDIQSLVLEI GTNVSTT+IT
Sbjct: 1552 MFKNTFQSGFLSILYSIGSKPLQIWDKKVRNGHIKRITDNDIQSLVLEIVGTNVSTTFIT 1373

Query: 61   CPADPKKTLGIKLPFLVMIIKNLKKYFTFEVQVLDDKNVRRRFRASNYQSTTRVKPFICT 120
            CPADPKKTLGIKLPFLVMIIKNLKKYFTFEVQVLDDKNVRRRFRASNYQSTTRVKPFICT
Sbjct: 1372 CPADPKKTLGIKLPFLVMIIKNLKKYFTFEVQVLDDKNVRRRFRASNYQSTTRVKPFICT 1193

Query: 121  MPMRLDDGWNQIQFNLSDFTRRAYGTNYIETLRVQIHANCRIRRVYFSDRLYSEDELPAE 180
            MPMRLDDGWNQIQFNLSDFTRRAYGTNYIETLRVQIHANCRIRRVYFSDRLYSEDELPAE
Sbjct: 1192 MPMRLDDGWNQIQFNLSDFTRRAYGTNYIETLRVQIHANCRIRRVYFSDRLYSEDELPAE 1013

Query: 181  FKLYLPVQ 188
            FKLYLP+Q
Sbjct: 1012 FKLYLPLQ 989
>07552
          Length = 1455

 Score =  278 bits (710), Expect = 1e-75,   Method: Compositional matrix adjust.
 Identities = 132/136 (97%), Positives = 134/136 (98%)
 Frame = -2

Query: 55   STTYITCPADPKKTLGIKLPFLVMIIKNLKKYFTFEVQVLDDKNVRRRFRASNYQSTTRV 114
            STT+ITCPADPKKTLGIKLPFLVMIIKNLKKYFTFEVQVLDDKNVRRRFRASNYQSTTRV
Sbjct: 1454 STTFITCPADPKKTLGIKLPFLVMIIKNLKKYFTFEVQVLDDKNVRRRFRASNYQSTTRV 1275

Query: 115  KPFICTMPMRLDDGWNQIQFNLSDFTRRAYGTNYIETLRVQIHANCRIRRVYFSDRLYSE 174
            KPFICTMPMRLDDGWNQIQFNLSDFTRRAYGTNYIETLRVQIHANCRIRRVYFSDRLYSE
Sbjct: 1274 KPFICTMPMRLDDGWNQIQFNLSDFTRRAYGTNYIETLRVQIHANCRIRRVYFSDRLYSE 1095

Query: 175  DELPAEFKLYLPVQNK 190
            +ELPAEFKLYLPV  K
Sbjct: 1094 EELPAEFKLYLPVTKK 1047
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|26326643|dbj|BAC27065.1| unnamed protein product [Mus
musculus]
         (836 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

15907                                                                 389   e-108
16054                                                                 211   1e-54
30195                                                                 108   7e-24
26962                                                                  32   0.77 
>15907
          Length = 905

 Score =  389 bits (1000), Expect = e-108,   Method: Compositional matrix adjust.
 Identities = 177/296 (59%), Positives = 230/296 (77%)
 Frame = +1

Query: 538 DASQVIGPLTEGQKRNVGVVNSLFKLHQSVTKVVASQSSFSATAEQTIMSALKTIHDLMG 597
           +ASQVIGP + GQ RN   VN+LF+ H +V+KV++  + F   A  ++ ++L+ +  LMG
Sbjct: 1   EASQVIGPPSAGQNRNSSTVNTLFQFHMAVSKVLSGLNHFPEEARTSVDASLEKVGQLMG 180

Query: 598 NAIQPLLTSVADAIEAIIITMHQEDFSGASSSSGKPDVPCSLYMKELQGFIARVMNDYFK 657
            AI PLL+S++DA+EAII+TMHQEDFSG + +  +   PCSL+MKELQGFI+R   DY  
Sbjct: 181 AAISPLLSSLSDALEAIILTMHQEDFSGPAPAGNQEAAPCSLFMKELQGFISRCQADYLS 360

Query: 658 HFECMDFVFDNTEAIAQRAIELFIRNASLIRPLGEGGKLRLAADFAQMELAVGPLCRRVS 717
            F C DFV D+   +A+  +ELF+R+ASLIRPLGEGGKLRLAADFAQME+A+ P CRRV+
Sbjct: 361 PFMCRDFVMDHLLPVARHCVELFVRHASLIRPLGEGGKLRLAADFAQMEMAISPFCRRVA 540

Query: 718 DLGKSYRMLRSFRPLLFQTSEHVADSPAVGDIIPFSIIIQFLFTRAPAELKSPFQRAEWS 777
           DLG+ YR+LR+FRPLLFQT EHVA SPA+G+IIP+S  + FLF RAPAEL+SP Q ++WS
Sbjct: 541 DLGRDYRILRAFRPLLFQTVEHVAQSPALGEIIPYSCALHFLFARAPAELRSPHQVSDWS 720

Query: 778 HARFSQWLDDHPSEKDRLLLLRGALEAYVQSVRSRDGKEFAPVYPIMVQLLQKAMY 833
            +R+S WLDDHPSE DRL  ++GALEAY + VR R  KE+APVYPIM+ LLQK ++
Sbjct: 721 VSRYSAWLDDHPSEADRLQFIKGALEAYAKLVRQRQSKEYAPVYPIMLDLLQKGLH 888
>16054
          Length = 739

 Score =  211 bits (537), Expect = 1e-54,   Method: Compositional matrix adjust.
 Identities = 114/212 (53%), Positives = 139/212 (65%), Gaps = 15/212 (7%)
 Frame = -1

Query: 287 GPGRAAMPTPGSTAGFRASLWTNMEKLMDHICAACGQVQHLQKVLTKKRDPVSHICFIEE 346
           GPGRAAM  PG+TA  RASLWTNMEKLMD I +AC QVQHLQKVL KKRDPV+H+CFI+E
Sbjct: 631 GPGRAAMAAPGNTAAMRASLWTNMEKLMDSIYSACAQVQHLQKVLAKKRDPVTHVCFIDE 452

Query: 347 IIK--DGQPEILYMFWNAVTLALSSHFHSATNSSMFLKQAFEGEYPKLLRLYNDLWKRLQ 404
           + K   G   I+  FW  VT  L+  F+ A  SS FLKQAFEGEYPKLLRLY DLW+RLQ
Sbjct: 451 LAKHRQGNVNIVQAFWEDVTRMLTKEFNDAAESSSFLKQAFEGEYPKLLRLYCDLWRRLQ 272

Query: 405 QSSQNTQGTFSPSGTPDLCVDLPHMEDDTQDMYRLKRPD---YDPEKALKDSLQPYEAAY 461
           Q S  T    + +G  +L    P   +  +D++         YD EKAL+D+L  +E AY
Sbjct: 271 QFSL-TMSVSASAGAAELVP--PESTEKEEDIFCAADKTNVAYDSEKALRDTLSEFETAY 101

Query: 462 LSKSLSRLFDP------INLVFPP----GGRN 483
           LS+SLSRLF P      + L+ PP    GG++
Sbjct: 100 LSRSLSRLF*PHQPGVHLQLL*PPHQ*RGGQH 5

 Score = 35.0 bits (79), Expect = 0.12,   Method: Composition-based stats.
 Identities = 14/24 (58%), Positives = 18/24 (75%)
 Frame = -2

Query: 470 FDPINLVFPPGGRNPPSSDELDGI 493
           FDPINLVF     +PP+S+E+D I
Sbjct: 75  FDPINLVFTSSSCDPPTSEEVDNI 4
>30195
          Length = 294

 Score =  108 bits (271), Expect = 7e-24,   Method: Compositional matrix adjust.
 Identities = 53/85 (62%), Positives = 66/85 (77%)
 Frame = -2

Query: 33  QAILQDDCYSEFLNEDFDVKTYTSQSIHQAVIAEQLAKLAQGISQLDKELHLQVVARHED 92
           Q I  DD + +FL+EDFDVK + ++ I    I EQLAKLA+GIS LDKE+H Q+V RH D
Sbjct: 257 QLINNDDAFKQFLSEDFDVKDHANKVIQGMAITEQLAKLAEGISLLDKEIHTQIVNRHGD 78

Query: 93  LLAQATGIESLEGVLQMMQTRIGAL 117
           LL+QAT +E+LEGVLQMMQTRI +L
Sbjct: 77  LLSQATSVETLEGVLQMMQTRIQSL 3
>26962
          Length = 398

 Score = 32.3 bits (72), Expect = 0.77,   Method: Composition-based stats.
 Identities = 12/27 (44%), Positives = 18/27 (66%)
 Frame = +3

Query: 647 FIARVMNDYFKHFECMDFVFDNTEAIA 673
           +IA V N +F HF C  F+ D +E++A
Sbjct: 102 YIAYVENSFFDHFRCTHFLVDLSESLA 182
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6753670|ref|NP_034202.1| dolichol-phosphate (beta-D)
mannosyltransferase 1 [Mus musculus]
         (260 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

01373                                                                 372   e-108
04191                                                                 270   3e-73
20453                                                                  55   2e-08
32642                                                                  27   9.7  
>01373
          Length = 1402

 Score =  372 bits (955), Expect(2) = e-108,   Method: Compositional matrix adjust.
 Identities = 171/213 (80%), Positives = 195/213 (91%)
 Frame = -2

Query: 48   VKSFSESAINYEIIIIDDGSPDGTREVAEQLAEIYGPDRILLRPREKKLGLGTAYIHGIK 107
             K FSES  ++EII+IDDGSPDGT +VAE+L  IYG DRI+LRPR KKLGLGTAY+HGIK
Sbjct: 1335 CKDFSESGYDFEIIVIDDGSPDGTLQVAEELQRIYGKDRIVLRPRGKKLGLGTAYVHGIK 1156

Query: 108  HATGNYVIIMDADLSHHPKFIPEFIRKQKEGNFDIVSGTRYKGNGGVYGWDLKRKIISRG 167
            HATGN++ IMDAD+SHHPKFIPEFI+KQ+EGN+D+V+GTRY G+GGV+GWDLKRK ISRG
Sbjct: 1155 HATGNFIFIMDADMSHHPKFIPEFIKKQEEGNYDVVTGTRYSGDGGVFGWDLKRKCISRG 976

Query: 168  ANFITQILLRPGASDLTGSFRLYRKEVLQKLIEKCVSKGYVFQMEMIVRARQMNYTIGEV 227
            ANFITQ+LLRPG SDLTGSFRLYRKEVLQ+LI+ CVSKGYVFQMEMIVRARQ +Y+IGEV
Sbjct: 975  ANFITQVLLRPGVSDLTGSFRLYRKEVLQRLIDSCVSKGYVFQMEMIVRARQFHYSIGEV 796

Query: 228  PISFVDRVYGESKLGGNEIVSFLKGLLTLFATT 260
            PISFVDRVYGESKLGG E+V FLKG+L LFATT
Sbjct: 795  PISFVDRVYGESKLGGQEVVDFLKGVLYLFATT 697

 Score = 37.7 bits (86), Expect(2) = e-108,   Method: Compositional matrix adjust.
 Identities = 18/28 (64%), Positives = 19/28 (67%)
 Frame = -3

Query: 26   KYSVLLPTYNERENLPLIVWLLVKSFSE 53
            KYSVLLPTY      P IVWLLVK F +
Sbjct: 1400 KYSVLLPTYEVEXKPPFIVWLLVKIFQK 1317
>04191
          Length = 616

 Score =  270 bits (691), Expect = 3e-73,   Method: Compositional matrix adjust.
 Identities = 123/149 (82%), Positives = 140/149 (93%)
 Frame = +1

Query: 112 NYVIIMDADLSHHPKFIPEFIRKQKEGNFDIVSGTRYKGNGGVYGWDLKRKIISRGANFI 171
           N++ IMDAD+SHHPKFIPEFI+KQ+EGN+D+V+GTRY G+GGV+GWDLKRK ISRGANFI
Sbjct: 1   NFIFIMDADMSHHPKFIPEFIKKQEEGNYDVVTGTRYSGDGGVFGWDLKRKCISRGANFI 180

Query: 172 TQILLRPGASDLTGSFRLYRKEVLQKLIEKCVSKGYVFQMEMIVRARQMNYTIGEVPISF 231
           TQ+LLRPG SDLTGSFRLYRKEVLQ+LI+ CVSKGYVFQMEMIVRARQ +Y+IGEVPISF
Sbjct: 181 TQVLLRPGVSDLTGSFRLYRKEVLQRLIDSCVSKGYVFQMEMIVRARQFHYSIGEVPISF 360

Query: 232 VDRVYGESKLGGNEIVSFLKGLLTLFATT 260
           VDRVYGESKLGG E+V FLKG+L LFATT
Sbjct: 361 VDRVYGESKLGGQEVVDFLKGVLYLFATT 447
>20453
          Length = 462

 Score = 55.5 bits (132), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 33/98 (33%), Positives = 53/98 (54%), Gaps = 5/98 (5%)
 Frame = +2

Query: 28  SVLLPTYNERENLPLIV-----WLLVKSFSESAINYEIIIIDDGSPDGTREVAEQLAEIY 82
           SV++P YNE + LP ++     +L  K+  +    YEII++ DGS D T  VA + ++I+
Sbjct: 155 SVIVPAYNEEQRLPAMLDECLGFLNEKAAKQPDFTYEIIVVSDGSSDATVSVALKYSKIH 334

Query: 83  GPDRILLRPREKKLGLGTAYIHGIKHATGNYVIIMDAD 120
           G D+  +    +  G G A   G+  A G  ++  DAD
Sbjct: 335 GADKFRVLELVENRGKGGAVRLGMLSARGRQLLFADAD 448
>32642
          Length = 627

 Score = 26.6 bits (57), Expect = 9.7,   Method: Compositional matrix adjust.
 Identities = 24/84 (28%), Positives = 35/84 (41%), Gaps = 4/84 (4%)
 Frame = +2

Query: 57  NYEIIIIDDGSPDGTREVAEQLAEIYGPDRILLRPRE----KKLGLGTAYIHGIKHATGN 112
           N  ++I D+GSP GTR        I  P   +LR +E    K L L T ++  I      
Sbjct: 200 NNVVLIEDNGSPVGTR--------ITVPVPSMLRSKEGDFTKILSLATKFV*AIIWGVYF 355

Query: 113 YVIIMDADLSHHPKFIPEFIRKQK 136
           YV+    D      ++P     Q+
Sbjct: 356 YVLSSFEDPPRQMTYVPHLSYXQQ 427
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|76559903|ref|NP_079681.2| hypothetical protein
LOC66184 [Mus musculus]
         (262 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

02793                                                                 388   e-108
33444                                                                 126   7e-30
00106                                                                 112   2e-25
24890                                                                  59   2e-09
36799                                                                  28   4.5  
>02793
          Length = 980

 Score =  388 bits (996), Expect = e-108,   Method: Compositional matrix adjust.
 Identities = 182/259 (70%), Positives = 218/259 (84%)
 Frame = -3

Query: 3   RGPKKHLKRVAAPRHWMLDKLTGVFAPRPSAGPHRLRECLPLAIFLRNRLKYALTGDEVK 62
           RG +K LKR  AP+ WMLDKL G FAP+PSAGPH+ RECLP+AI LRNRLKYALT DE K
Sbjct: 870 RGRRKSLKRCTAPKSWMLDKLGGNFAPKPSAGPHKSRECLPMAILLRNRLKYALTYDECK 691

Query: 63  KICMQRLIKVDGKVRTDVAYPAGFMDVISIDKSGENFRLVYDTKGRFAVHRITPEEAKYK 122
           KI MQRL+KVDG+VRTD  YP GFMDVI+I+++ E FR++YD KGRF VHRI  EEAKYK
Sbjct: 690 KIVMQRLVKVDGRVRTDKTYPCGFMDVITIERTNEFFRILYDVKGRFVVHRIKAEEAKYK 511

Query: 123 LCKVRKVFVGTKGIPHLVTHDARTIRYPDPLIKVNDTVQISLDSGKITDAIKFDTGNLCM 182
           LC+V++V VG KG+P +VT D RTIRYPDPL+KVND++ + + +GK+ D IKFD+GNL M
Sbjct: 510 LCRVKRVQVGPKGVPFIVTDDGRTIRYPDPLVKVNDSIVLDIATGKMKDFIKFDSGNLVM 331

Query: 183 VTGGANLGRIGVITNRERHPGSFDVVHVKDANGNGFATRLSNIFVIGKGNKPWISLPRGK 242
           VTGG NLGR+G IT+RERHPGSFD+VH+KD  G+ FATRLS +FVIGKG+K WISLP+GK
Sbjct: 330 VTGGHNLGRVGTITHRERHPGSFDIVHIKDTLGHTFATRLSYVFVIGKGSKQWISLPKGK 151

Query: 243 GIRLTIAEERDKRLAAKQS 261
           G+RLTIAEERD+RLAAK  
Sbjct: 150 GVRLTIAEERDRRLAAKSQ 94
>33444
          Length = 354

 Score =  126 bits (317), Expect = 7e-30,   Method: Compositional matrix adjust.
 Identities = 55/75 (73%), Positives = 70/75 (93%)
 Frame = -1

Query: 185 GGANLGRIGVITNRERHPGSFDVVHVKDANGNGFATRLSNIFVIGKGNKPWISLPRGKGI 244
           GG NLGR+G + NRERHPGSFD+VH+KD+ G+ FATRL+N+F+IGKGNKP+ISLP+GKG+
Sbjct: 354 GGRNLGRVGTVVNRERHPGSFDIVHIKDSQGHVFATRLTNVFIIGKGNKPYISLPKGKGV 175

Query: 245 RLTIAEERDKRLAAK 259
           +L+I+EERDKRLAAK
Sbjct: 174 KLSISEERDKRLAAK 130
>00106
          Length = 473

 Score =  112 bits (279), Expect = 2e-25,   Method: Compositional matrix adjust.
 Identities = 50/68 (73%), Positives = 61/68 (89%)
 Frame = +2

Query: 194 VITNRERHPGSFDVVHVKDANGNGFATRLSNIFVIGKGNKPWISLPRGKGIRLTIAEERD 253
           ++T+RERHPGSFD+VH+KD  G+ FATRLS +FVIGKG+K WISLP+GKG+RLTIAEERD
Sbjct: 182 LLTHRERHPGSFDIVHIKDTLGHTFATRLSYVFVIGKGSKQWISLPKGKGVRLTIAEERD 361

Query: 254 KRLAAKQS 261
           +RLAAK  
Sbjct: 362 RRLAAKSQ 385
>24890
          Length = 425

 Score = 58.9 bits (141), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 26/38 (68%), Positives = 30/38 (78%)
 Frame = +1

Query: 3   RGPKKHLKRVAAPRHWMLDKLTGVFAPRPSAGPHRLRE 40
           RG +K LKR  AP+ WMLDKL G FAP+PSAGPH+ RE
Sbjct: 310 RGRRKSLKRCTAPKSWMLDKLGGNFAPKPSAGPHKSRE 423
>36799
          Length = 646

 Score = 27.7 bits (60), Expect = 4.5,   Method: Compositional matrix adjust.
 Identities = 11/30 (36%), Positives = 17/30 (56%)
 Frame = -3

Query: 208 VHVKDANGNGFATRLSNIFVIGKGNKPWIS 237
           +HV++ N N F  R+ N  ++     PWIS
Sbjct: 374 IHVQELNPNHFDARVINASLLRSARCPWIS 285
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|190684669|ref|NP_906273.3| erythrocyte protein band
4.1 isoform 1 [Mus musculus]
         (858 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

00990                                                                 384   e-107
18811                                                                 186   3e-47
11374                                                                 177   2e-44
17332                                                                 146   3e-35
13951                                                                  54   1e-16
28244                                                                  77   4e-14
08363                                                                  65   8e-11
03469                                                                  64   2e-10
05888                                                                  49   7e-06
12829                                                                  30   3.1  
>00990
          Length = 3161

 Score =  384 bits (987), Expect = e-107,   Method: Compositional matrix adjust.
 Identities = 183/368 (49%), Positives = 260/368 (70%), Gaps = 5/368 (1%)
 Frame = +3

Query: 179 EECSGTEVKEDPESRAEREPEASQKPVRRHRNMHCKVSLLDDTVYECVVEKHAKGQDLLK 238
           ++ S +EV E+ +    ++   S +  R  +  + +V LLD       ++++A+G++L  
Sbjct: 162 DKIS*SEV*EESQ*NGRQDGSKSPQKQRTGKGFNYEVVLLDGEHVNFELDRNAEGRELFD 341

Query: 239 RVCEHLNLLEEDYFGLALWDSATS---KTWLDSAKEIKKQVRGVPWNFTFNVKFYPPDPA 295
           +VC+HL+L+E+DYFGL   D   S   K WL   K I KQ +G PW F F +KFYPPDP 
Sbjct: 342 KVCQHLDLIEKDYFGLQFVDERISNHLKCWLSPDKRISKQKKGGPWLFDFALKFYPPDPT 521

Query: 296 QLTEDITRYYLCLQLRQDIVAGRLPCSFATLALLGSYTIQSELGDYDPELH-GMDYVSDF 354
           QL E +TR+ + LQ R+DI++G+LP ++ T A+LGSY +Q+++GDYDP  H G++Y+ D 
Sbjct: 522 QLRESLTRWLVVLQTRRDILSGKLPATYLTQAMLGSYCVQADVGDYDPNEHRGVEYIRDT 701

Query: 355 KLAPNQTKELEEKVMELHKSYRSMTPAQADLEFLENAKKLSMYGVDLHKAKDLEGVDIIL 414
             APNQT +L EK++ELH+ ++  TP +A+  FLENAKKL+MYGVDLH A+D+  VDI+L
Sbjct: 702 PFAPNQTIDLLEKIVELHRQHKGQTPDEAETNFLENAKKLAMYGVDLHAAQDVNNVDIML 881

Query: 415 GVCSSGLLVYKDKLRINRFPWPKVLKISYKRSSFFIKIRPGEQEHYESTIGFKLPSYRAA 474
           GVC+SGL VY++KLRI+RF WPK+LKISYKR  F+IK+RP +    E++  FKL ++R A
Sbjct: 882 GVCASGLQVYREKLRISRFVWPKILKISYKRRQFYIKVRPSDNSAMENSFCFKLATHRLA 1061

Query: 475 KKLWKVCVEHHTFFRLTSTD-TIPKSKFLALGSKFRYSGRTQAQTRQASALIDRPAPHFE 533
           K+LWK+CVEHH FFRL   + +   + F  LGSKFRYSGRT  QTRQ+S ++DRP P+FE
Sbjct: 1062KRLWKICVEHHAFFRLREAEQSQNAAMFPRLGSKFRYSGRTLYQTRQSSQILDRPNPYFE 1241

Query: 534 RTASKRAS 541
           R+   R+S
Sbjct: 1242RSQPARSS 1265

 Score = 42.0 bits (97), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 21/55 (38%), Positives = 33/55 (60%), Gaps = 2/55 (3%)
 Frame = +3

Query: 802  KGGISETRIEKRIVITG--DADIDHDQVLVQAIKEAKEQHPDMSVTKVVVHQETE 854
            K GI  TR+E ++V++   D + D+D  L  AI+   E +PDMSV ++   Q+ E
Sbjct: 2145 KDGIQHTRVEHKVVLSSADDEEFDYDAALADAIRSVTEFNPDMSVERIECVQQIE 2309
>18811
          Length = 478

 Score =  186 bits (472), Expect = 3e-47,   Method: Compositional matrix adjust.
 Identities = 79/134 (58%), Positives = 108/134 (80%)
 Frame = -2

Query: 346 HGMDYVSDFKLAPNQTKELEEKVMELHKSYRSMTPAQADLEFLENAKKLSMYGVDLHKAK 405
           HG DY+ D   APNQ  EL EK++ELH+ ++  TP +A++ +LENAKKLSMYGVDLH A+
Sbjct: 402 HGADYIKDIPFAPNQAPELLEKIVELHRQHKGQTPDEAEVNYLENAKKLSMYGVDLHAAQ 223

Query: 406 DLEGVDIILGVCSSGLLVYKDKLRINRFPWPKVLKISYKRSSFFIKIRPGEQEHYESTIG 465
           D+  VDI+LGVCSSGL VY+DKLRI+RF WPK++KISYKR  F++K+RP + +  E+++ 
Sbjct: 222 DVNNVDIMLGVCSSGLQVYRDKLRISRFVWPKIIKISYKRKHFYVKVRPADNKGLETSVS 43

Query: 466 FKLPSYRAAKKLWK 479
           F+LP++R AK+LWK
Sbjct: 42  FRLPTHRLAKRLWK 1
>11374
          Length = 800

 Score =  177 bits (449), Expect = 2e-44,   Method: Compositional matrix adjust.
 Identities = 80/140 (57%), Positives = 104/140 (74%), Gaps = 1/140 (0%)
 Frame = +3

Query: 401 LHKAKDLEGVDIILGVCSSGLLVYKDKLRINRFPWPKVLKISYKRSSFFIKIRPGEQEHY 460
           LH A+D+  VDI+LGVC+SGL VY++KLRI+RF WPK+LKISYKR  F+IK+RP +    
Sbjct: 3   LHAAQDVNNVDIMLGVCASGLQVYREKLRISRFVWPKILKISYKRRQFYIKVRPSDNSAM 182

Query: 461 ESTIGFKLPSYRAAKKLWKVCVEHHTFFRLTSTD-TIPKSKFLALGSKFRYSGRTQAQTR 519
           E++  FKL ++R AK+LWK+CVEHH FFRL   + +   + F  LGSKFRYSGRT  QTR
Sbjct: 183 ENSFCFKLATHRLAKRLWKICVEHHAFFRLREAEQSQNAAMFPRLGSKFRYSGRTLYQTR 362

Query: 520 QASALIDRPAPHFERTASKR 539
            +S  +DRP P+FER+   R
Sbjct: 363 HSSQTLDRPDPYFERSQPAR 422
>17332
          Length = 473

 Score =  146 bits (369), Expect = 3e-35,   Method: Composition-based stats.
 Identities = 74/157 (47%), Positives = 101/157 (64%), Gaps = 2/157 (1%)
 Frame = +2

Query: 219 DDTVYECVVEKHAKGQDLLKRVCEHLNLLEEDYFGLALWDSATSKTWLDSAKEIKKQVRG 278
           DD+ ++  V+ + KG  L ++VCE LNL E+DYFGL   D++    WLD  K +  Q++G
Sbjct: 2   DDSDHQLQVKGNWKGILLQEKVCELLNLHEKDYFGLRFIDASGQTHWLDGNKSLSSQLKG 181

Query: 279 --VPWNFTFNVKFYPPDPAQLTEDITRYYLCLQLRQDIVAGRLPCSFATLALLGSYTIQS 336
              P    F VKFY  DP +L E+ITRY   LQ++QDI+ GRLP +F   + L +Y +QS
Sbjct: 182 CQTPHKLYFGVKFYAADPCKLREEITRYLFFLQVKQDILQGRLPVTFDEASELCAYAVQS 361

Query: 337 ELGDYDPELHGMDYVSDFKLAPNQTKELEEKVMELHK 373
           ELGD+DP  H   YVS+F   PNQT+ELE +V  LH+
Sbjct: 362 ELGDFDPRQHTDGYVSEFCFIPNQTEELERRVAGLHR 472
>13951
          Length = 720

 Score = 53.5 bits (127), Expect(2) = 1e-16,   Method: Compositional matrix adjust.
 Identities = 29/88 (32%), Positives = 48/88 (54%), Gaps = 3/88 (3%)
 Frame = -2

Query: 190 PESRAEREPEASQKPVRRHRNMHCKVSLLDDTVYECVVEKHAKGQDLLKRVCEHLNLLEE 249
           P    ++  + S +  R  +  + +V LLD       ++++A+G++L  +VC+HL+L+E+
Sbjct: 455 PSEMGDKTEDKSPQKQRTGKGFNYEVVLLDGEHVNFELDRNAEGRELFDKVCQHLDLIEK 276

Query: 250 DYFGLALWDSATS---KTWLDSAKEIKK 274
           DYFGL   D   S   K WL   K I K
Sbjct: 275 DYFGLQFVDERISNHLKCWLSPDKRISK 192

 Score = 51.6 bits (122), Expect(2) = 1e-16,   Method: Composition-based stats.
 Identities = 23/50 (46%), Positives = 31/50 (62%)
 Frame = -1

Query: 270 KEIKKQVRGVPWNFTFNVKFYPPDPAQLTEDITRYYLCLQLRQDIVAGRL 319
           K+ + + +G PW F F +KFYPPDP QL E +TR+ + L      VAG L
Sbjct: 204 KDFQNRKKGGPWLFDFALKFYPPDPTQLRESLTRWLVVLH-----VAGEL 70
>28244
          Length = 422

 Score = 76.6 bits (187), Expect = 4e-14,   Method: Composition-based stats.
 Identities = 46/124 (37%), Positives = 66/124 (53%), Gaps = 4/124 (3%)
 Frame = -1

Query: 422 LVYKDKLRINRFPWPKVLKISYKRSSF-FIKIRPGEQEHYESTIG-FKLPSYRAAKKLWK 479
           LV++   +I  F WPK+ ++ +K      + +   E    +  I  F+L S +A K LWK
Sbjct: 422 LVFEGNXKIGLFFWPKMTRLDFKGKKLTLVAVEDDENGQSQDHIFVFRLQSEKACKHLWK 243

Query: 480 VCVEHHTFFRLTSTDTIPKSK--FLALGSKFRYSGRTQAQTRQASALIDRPAPHFERTAS 537
             VEHH FFRL      P ++  F  +GS+FRYSGRT+ QT   +    R +  FER  S
Sbjct: 242 CAVEHHAFFRLKGPVQGPNARQNFFRMGSRFRYSGRTEYQTSTMNRA--RRSVKFERKPS 69

Query: 538 KRAS 541
           +R S
Sbjct: 68  QRYS 57
>08363
          Length = 1878

 Score = 65.5 bits (158), Expect = 8e-11,   Method: Compositional matrix adjust.
 Identities = 47/133 (35%), Positives = 66/133 (49%), Gaps = 1/133 (0%)
 Frame = +1

Query: 723 PPLVKTQTVTISDTANAVKSEIPTKDVPIVHTETKTITYEAAQTEDSNGDLDPGVLLXXX 782
           PP V T++V        V   +PTK+VP+V TET+T+TYE    E    D + GVL+   
Sbjct: 115 PPTVATESVHYQPDVEEVP--VPTKNVPLVKTETRTVTYER---EGFPFDGEDGVLVSAS 279

Query: 783 XXXXXXXXXXXXXXXXXXVKGGISETRIEKRIVITG-DADIDHDQVLVQAIKEAKEQHPD 841
                              K G+ ETR+E R+V++  D D D+D  L  AI+   E +PD
Sbjct: 280 SHSTRMQTIETTTYKTE--KDGVQETRVEHRVVLSSTDDDFDYDAALADAIRSVTEFNPD 453

Query: 842 MSVTKVVVHQETE 854
           MSV ++   Q  E
Sbjct: 454 MSVERIECVQXIE 492
>03469
          Length = 1275

 Score = 64.3 bits (155), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 41/112 (36%), Positives = 59/112 (52%), Gaps = 1/112 (0%)
 Frame = -3

Query: 744  IPTKDVPIVHTETKTITYEAAQTEDSNGDLDPGVLLXXXXXXXXXXXXXXXXXXXXXVKG 803
            +PTK+VP+V TET+T+TYE    E    D + GVL+                      K 
Sbjct: 1258 VPTKNVPLVKTETRTVTYER---EGFPFDGEDGVLVSASSHSTRMQTIETTTYKTE--KD 1094

Query: 804  GISETRIEKRIVITG-DADIDHDQVLVQAIKEAKEQHPDMSVTKVVVHQETE 854
            G+ ETR+E R+V++  D D D+D  L  AI+   E +PDMSV ++   Q+ E
Sbjct: 1093 GVQETRVEHRVVLSSTDDDFDYDAALADAIRSVTEFNPDMSVERIECVQQIE 938
>05888
          Length = 490

 Score = 49.3 bits (116), Expect = 7e-06,   Method: Compositional matrix adjust.
 Identities = 22/36 (61%), Positives = 26/36 (72%)
 Frame = -2

Query: 504 LGSKFRYSGRTQAQTRQASALIDRPAPHFERTASKR 539
           LGSKFRYSGRT  Q R +S  +DRP P+FER+   R
Sbjct: 489 LGSKFRYSGRTLYQARHSSQTLDRPDPYFERSQPAR 382
>12829
          Length = 2357

 Score = 30.4 bits (67), Expect = 3.1,   Method: Compositional matrix adjust.
 Identities = 13/40 (32%), Positives = 24/40 (60%)
 Frame = -2

Query: 126  EDIILKAPIAAPEPELKTDPSLDLHSLSSIETQPAQEEHR 165
            E+I+L +P+A+P+P+    PS+ +  + S   Q A+   R
Sbjct: 1669 EEIVLVSPLASPQPDFPMSPSVSVLGVPSPRIQTARSPSR 1550
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|20270275|ref|NP_620084.1| methylenetetrahydrofolate
dehydrogenase 1 [Mus musculus]
         (935 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

11972                                                                 385   e-107
06310                                                                 207   2e-53
05632                                                                  87   2e-17
32635                                                                  32   0.99 
14749                                                                  32   0.99 
07549                                                                  31   2.5  
>11972
          Length = 736

 Score =  385 bits (988), Expect = e-107,   Method: Compositional matrix adjust.
 Identities = 185/239 (77%), Positives = 207/239 (86%)
 Frame = -3

Query: 550 PTEKGHTRTAQFDISVASEIMAVLALTSSLEDMRERLGRMVVASSKKGEPISCEDLGVSG 609
           P EK  TR  QFDI+VASEIMA+LALTS L DMRERLG+MVVASSK GEP++ +DLGVSG
Sbjct: 734 PQEKNMTRETQFDITVASEIMAILALTSDLRDMRERLGKMVVASSKAGEPVTADDLGVSG 555

Query: 610 TLTVLMKDAIKPNLMQTLEGTPVFVHAGPFANIAHGNSSIIADRIALKLVGPEGFVVTEA 669
            LTVLM+DA++PNLMQTLEGTPVFVHAGPFANIAHGNSSI+AD++ALK+VG +GFVVTEA
Sbjct: 554 ALTVLMRDALRPNLMQTLEGTPVFVHAGPFANIAHGNSSILADKLALKIVGEKGFVVTEA 375

Query: 670 GFGADIGMEKFFNIKCRYSGLQPHVVVLVATVRALKMHGGGPTVTAGLPLPKAYTEEDLD 729
           GFGADIGMEKFFNIKCRYSGL P+ VVLVATVRALKMHGGGPTVTAG+PLPK YTEE+L+
Sbjct: 374 GFGADIGMEKFFNIKCRYSGLVPNAVVLVATVRALKMHGGGPTVTAGVPLPKDYTEENLE 195

Query: 730 LVEKGFSNLRKQIENARMFGXXXXXXXXXFKTDTDAELDLVSRLSREHGAFDAVKCTHW 788
           LVEKG SNL KQIENA  FG         F TDT AEL+LV RL+RE+GAFDAV  +HW
Sbjct: 194 LVEKGCSNLLKQIENANYFGIPVVVAVNAFATDTQAELELVQRLARENGAFDAVISSHW 18
>06310
          Length = 1575

 Score =  207 bits (526), Expect = 2e-53,   Method: Compositional matrix adjust.
 Identities = 92/126 (73%), Positives = 112/126 (88%)
 Frame = +2

Query: 809 PSSFQLLYDLKLSIEDKIRIIAQRIYGADDIELLPEAQNKAEIYTKQGFGNLPICMAKTH 868
           PS+FQ LYD+KL IE+KI IIA++IYGAD +EL P A+ + E YT+QGF +LPICMAKTH
Sbjct: 8   PSNFQFLYDVKLPIEEKIAIIAKKIYGADGVELEPLAKEQVERYTRQGFNDLPICMAKTH 187

Query: 869 LSLSHNPEQKGVPTGFVLPIRDIRASVGAGFLYPLVGTMSTMPGLPTRPCFYDIDLDPET 928
           LSLSH PE+KG P GFVLPIR++RAS+GAGF+YPL+GTMSTMPGLPTRPCFYDID+DP+T
Sbjct: 188 LSLSHMPEKKGAPKGFVLPIREVRASIGAGFIYPLIGTMSTMPGLPTRPCFYDIDIDPDT 367

Query: 929 EQVNGL 934
           E++ GL
Sbjct: 368 EEIVGL 385
>05632
          Length = 930

 Score = 87.4 bits (215), Expect = 2e-17,   Method: Composition-based stats.
 Identities = 35/45 (77%), Positives = 44/45 (97%)
 Frame = -1

Query: 890 DIRASVGAGFLYPLVGTMSTMPGLPTRPCFYDIDLDPETEQVNGL 934
           ++RAS+GAGF+YPL+GTMSTMPGLPTRPCFYDID+DP+TE++ GL
Sbjct: 930 EVRASIGAGFIYPLIGTMSTMPGLPTRPCFYDIDIDPDTEEIVGL 796
>32635
          Length = 574

 Score = 32.3 bits (72), Expect = 0.99,   Method: Composition-based stats.
 Identities = 13/39 (33%), Positives = 23/39 (58%)
 Frame = +1

Query: 885 VLPIRDIRASVGAGFLYPLVGTMSTMPGLPTRPCFYDID 923
           + P+RD+R+S G  +L       +T+  +P+R   YD+D
Sbjct: 22  LFPVRDMRSSSGDSYLMNTHKFSNTVLAMPSRRQLYDVD 138
>14749
          Length = 810

 Score = 32.3 bits (72), Expect = 0.99,   Method: Composition-based stats.
 Identities = 13/39 (33%), Positives = 23/39 (58%)
 Frame = -3

Query: 885 VLPIRDIRASVGAGFLYPLVGTMSTMPGLPTRPCFYDID 923
           + P+RD+R+S G  +L       +T+  +P+R   YD+D
Sbjct: 517 LFPVRDMRSSSGDSYLMNTHKFSNTVLAMPSRRQLYDVD 401
>07549
          Length = 949

 Score = 30.8 bits (68), Expect = 2.5,   Method: Compositional matrix adjust.
 Identities = 14/48 (29%), Positives = 22/48 (45%)
 Frame = +1

Query: 151 GCLELIKEAGVQIAGRHAVVVGRSKIVGAPMHDLLLWNNATVTTCHSK 198
           G L+L+K  G     RH   + + + +G P H    WN+   T   +K
Sbjct: 649 GRLDLVKNEGTXAEPRHHKPIDQPRPLGKPPHSHRQWNSVGHTDAKAK 792
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|56699423|ref|NP_035020.2| neural precursor cell
expressed, developmentally down-regulated gene 4 [Mus musculus]
         (887 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

05501                                                                 387   e-107
02386                                                                 305   6e-83
13725                                                                 219   4e-57
21239                                                                 103   3e-22
26162                                                                  88   2e-17
19738                                                                  79   8e-15
29179                                                                  65   1e-10
05524                                                                  52   1e-09
33148                                                                  50   4e-06
28454                                                                  44   4e-04
37652                                                                  43   7e-04
30322                                                                  39   0.009
31463                                                                  39   0.009
19350                                                                  39   0.011
01494                                                                  38   0.017
07591                                                                  37   0.032
13896                                                                  36   0.065
22144                                                                  36   0.087
14539                                                                  35   0.095
25750                                                                  35   0.13 
12851                                                                  35   0.14 
00178                                                                  35   0.16 
30040                                                                  34   0.27 
28393                                                                  31   1.7  
01656                                                                  30   2.9  
06273                                                                  30   5.9  
18322                                                                  29   6.6  
20379                                                                  29   7.9  
25445                                                                  29   8.4  
>05501
          Length = 1740

 Score =  387 bits (993), Expect = e-107,   Method: Compositional matrix adjust.
 Identities = 189/345 (54%), Positives = 254/345 (73%), Gaps = 2/345 (0%)
 Frame = -1

Query: 541  EDSYRRIMGVKRADLLKARLWIEFDGEKGLDYGGVAREWFFLISKEMFNPYYGLFEYSAT 600
            EDS+ +IM ++  DL + RL+I F GE+GLDYGGVAREWFF +S ++ NP Y LFEY++ 
Sbjct: 1680 EDSFAQIMRLQPFDL-RRRLYIIFKGEEGLDYGGVAREWFFHLSHDVLNPMYCLFEYASN 1504

Query: 601  DNYTLQINPNSGLCNEDHLSYFKFIGRVAGMAVYHGKLLDGFFIRPFYKMMLQKLITLHD 660
            +NY+LQINP S + N DHL YF+FIGR   MA+YHGK +D  F  PFYK ML K +TL D
Sbjct: 1503 NNYSLQINPASSV-NPDHLLYFRFIGRFIAMALYHGKFIDSGFTLPFYKRMLSKKLTLKD 1327

Query: 661  MESVDSEYYSSLRWILENDPTE--LDLRFIIDEELFGQTHQHELKTGGSEIVVTNKNKKE 718
            +E++D EY+ SL+W+ +N+  E  L+L F  D E+ G+   HELK GGSEI VT +NK+E
Sbjct: 1326 LETIDGEYFQSLQWVKDNNVEESGLELFFCADFEVLGKVENHELKPGGSEIKVTEENKEE 1147

Query: 719  YIYLVIQWRFVNRIQKQMAAFKEGFFELIPQDLIKIFDENELELLMCGLGDVDVNDWREH 778
            Y+ L+ QWRF   +++Q  AF EGF E++P   ++ FDE ELEL++CG+ +VDV+DW  +
Sbjct: 1146 YLNLMTQWRFSRGVEEQTKAFLEGFNEVVPLQWLQYFDERELELMLCGMQEVDVDDWERN 967

Query: 779  TKYKNGYSMNHQVIHWFWKAVWMMDSEKRIRLLQFVTGTSRVPMNGFAELYGSNGPQSFT 838
            T Y++ Y  N + + WFWK V  +D+EKR RLLQFVTGT R+P+ GFAEL GSNGPQ F 
Sbjct: 966  TIYRH-YQRNSKQVTWFWKFVREIDNEKRTRLLQFVTGTCRLPVGGFAELMGSNGPQRFC 790

Query: 839  VEQWGTPDKLPRAHTCFNRLDLPPYESFDELWDKLQMAIENTQGF 883
            +E+ G    LPR+HTCFNR+DLPPY S+++L +KL +AIE T+GF
Sbjct: 789  IEKVGKETWLPRSHTCFNRIDLPPYRSYEQLVEKLNLAIEETEGF 655
>02386
          Length = 2222

 Score =  305 bits (781), Expect = 6e-83,   Method: Compositional matrix adjust.
 Identities = 168/389 (43%), Positives = 244/389 (62%), Gaps = 13/389 (3%)
 Frame = +2

Query: 508 DYKRKYEFFRRKLKK------QTDIPNKFEMKLRRANILEDSYRRIMGVKRADLLKARLW 561
           D KR+Y  FR++L++      + D+P    + +RR ++ EDS+R +   +  D  K R +
Sbjct: 263 DVKRRY--FRQELERMEEGMRREDLP----VHVRREHVFEDSFRELFR-RNPDEWKQRFY 421

Query: 562 IEFDGEKGLDYGGVAREWFFLISKEMFNPYYGLFEYSATDNYTLQINPNSGLCNEDHLSY 621
           I F+GE+G D GG+ REW+ +IS+E+FN  Y LF+    D  T  INP+S   N +HLSY
Sbjct: 422 IVFEGEEGQDAGGLLREWYLIISREIFNENYVLFKRYPRDGVTYTINPSSHF-NSNHLSY 598

Query: 622 FKFIGRVAGMAVYHGKLLDGFFIRPFYKMMLQKLITLHDMESVDSEYYSSLRWILENDPT 681
           FKF+GR+   A+Y  KLL+ +F R FYK +L   +   DME  D  +Y SL ++LEND T
Sbjct: 599 FKFVGRIIAKAIYDNKLLECYFTRSFYKHVLGLPVKYTDMECEDIMFYQSLVFLLENDIT 778

Query: 682 EL-----DLRFIIDEELFGQTHQHELKTGGSEIVVTNKNKKEYIYLVIQWRFVNRIQKQM 736
           ++     DL F  + E FG     +L   GS I VT +NK+EY+ LV Q +    I++Q+
Sbjct: 779 DMGAALGDLNFSAEVEEFGVRETRDLIENGSNIGVTEENKREYVKLVCQMKMTGAIRQQL 958

Query: 737 AAFKEGFFELIPQDLIKIFDENELELLMCGLGDVDVNDWREHTKYKNGYSMNHQVIHWFW 796
            AF EGF+++IP+ L+ IF E ELELL+ GL  +D++D + +T+Y + Y      I WFW
Sbjct: 959 NAFLEGFYDIIPKKLVAIFTEQELELLISGLPTIDIDDLKANTEY-HKYQPTSLQIQWFW 1135

Query: 797 KAVWMMDSEKRIRLLQFVTGTSRVPMNGFAELYGSNGPQSFTVEQWG-TPDKLPRAHTCF 855
           +A+   D  +R   LQFVTGTS+VP+ GFA L G NG Q F + +   + D+LP AHTCF
Sbjct: 1136RALRSFDQAERANFLQFVTGTSKVPLQGFATLEGMNGHQKFQIHRDDRSTDRLPSAHTCF 1315

Query: 856 NRLDLPPYESFDELWDKLQMAI-ENTQGF 883
           N+LDLP YE++D+L   L +A+ E ++GF
Sbjct: 1316NQLDLPAYETYDKLRKMLLLAVSECSEGF 1402
>13725
          Length = 700

 Score =  219 bits (558), Expect = 4e-57,   Method: Compositional matrix adjust.
 Identities = 113/225 (50%), Positives = 154/225 (68%), Gaps = 1/225 (0%)
 Frame = +2

Query: 532 MKLRRANILEDSYRRIMGVKRADLLKARLWIEFDGEKGLDYGGVAREWFFLISKEMFNPY 591
           +++ R  I EDSYR++M + R+  L+ RL ++F GE+GLDYGGVAREWF+L+S EM NPY
Sbjct: 56  LEVSREEIFEDSYRQVMKM-RSKELRKRLMVKFHGEEGLDYGGVAREWFYLLSHEMLNPY 232

Query: 592 YGLFEYSATDNYTLQINPNSGLCNEDHLSYFKFIGRVAGMAVYHGKLLDGFFIRPFYKMM 651
           YGLF+YS  D YTLQINP+SG+ N +HLSYF F+GRV GMA++HG  LDG F  PFYK +
Sbjct: 233 YGLFQYSREDIYTLQINPDSGV-NPEHLSYFHFVGRVIGMAIFHGHYLDGGFTMPFYKQL 409

Query: 652 LQKLITLHDMESVDSEYYSSLRWILEND-PTELDLRFIIDEELFGQTHQHELKTGGSEIV 710
           L K  TL D+ESVD + + SL W+LEN+    L+  F ++   FG+  ++ELK GG++  
Sbjct: 410 LGKPATLEDLESVDPDLHRSLCWMLENNIENVLEHTFSVEHNSFGKLREYELKPGGNDTK 589

Query: 711 VTNKNKKEYIYLVIQWRFVNRIQKQMAAFKEGFFELIPQDLIKIF 755
           VT  NK EY+ L + WR +  I+ Q  A        + +DL+K F
Sbjct: 590 VTEDNKHEYVRLYVHWRLMRGIEAQFLA--------LXKDLMKSF 700
>21239
          Length = 1264

 Score =  103 bits (257), Expect = 3e-22,   Method: Compositional matrix adjust.
 Identities = 65/184 (35%), Positives = 92/184 (50%), Gaps = 3/184 (1%)
 Frame = +1

Query: 701 ELKTGGSEIVVTNKNKKEYIYLVIQWRFVNRIQKQMAAFKEGFFELIPQDLIKIFDENEL 760
           ELK GG +I VT  N  EY+ LVI W  V  + +Q  AF+EGF  +     ++ F   EL
Sbjct: 121 ELKKGGKDIPVTLHNLHEYLQLVIHWSLVEGVSRQFEAFREGFESVFSLSSLQCFYPEEL 300

Query: 761 ELLMCG--LGDVDVNDWREHTKYKNGYSMNHQVIHWFWKAVWMMDSEKRIRLLQFVTGTS 818
           E L CG   G  +V    E+ +  +GY+ + + + + ++ +   D +++   LQFVTG+ 
Sbjct: 301 EQLFCGSQWGPWEVKMLMENCRPDHGYTHDSKAVVFLYQLLASFDLQQQRHFLQFVTGSP 480

Query: 819 RVPMNGFAELYGSNGPQSFTVEQWGTPDK-LPRAHTCFNRLDLPPYESFDELWDKLQMAI 877
           R+P+ GF  L         T E    PD  LP   TC N L LP Y S D +  KL  A 
Sbjct: 481 RLPVGGFRSLTPPLTIVRKTFEAGENPDDFLPSVMTCVNYLKLPDYSSIDIMRHKLHTAA 660

Query: 878 ENTQ 881
              Q
Sbjct: 661 SEGQ 672
>26162
          Length = 608

 Score = 87.8 bits (216), Expect = 2e-17,   Method: Compositional matrix adjust.
 Identities = 55/164 (33%), Positives = 74/164 (45%), Gaps = 24/164 (14%)
 Frame = +1

Query: 362 LAVCGNPATSQPVTS-----SNHSSRGGSLQTCIFEEQPTLPVLLPTSSGLPPGWEEKQD 416
           L   G+ +T+ P        +   +R  S     F +  T          LP GWE + D
Sbjct: 28  LPTSGDGSTASPADPDHPLPNGWEARKDSQGRTYFVDHNTRTTTWERPQPLPAGWERRID 207

Query: 417 DRGRSYYVDHNSKTTTWSKPTMQD-------------------DPRSKIPAHLRGKTDSN 457
             GR YYVDHN++TTTW +P  +                    + R   P   +   D++
Sbjct: 208 QHGRVYYVDHNTRTTTWQRPNTEMVTNWNNWQQWRNNRTMDAMNQRFLFPQTAQPSVDND 387

Query: 458 DLGPLPPGWEERTHTDGRVFFINHNIKKTQWEDPRLQNVAITGP 501
            LGPL  GWE+RT   GRV+F+NH  + TQWEDPR Q V    P
Sbjct: 388 PLGPLLDGWEKRTDATGRVYFVNHKNRTTQWEDPRTQGVMQEDP 519

 Score = 49.3 bits (116), Expect = 6e-06,   Method: Compositional matrix adjust.
 Identities = 54/188 (28%), Positives = 75/188 (39%), Gaps = 9/188 (4%)
 Frame = +1

Query: 254 GWEERQDVLGRTYYVNHESRRTQWKRPSPXXXXXXXXXXXMQL-----QAQRAFTTRRQI 308
           GWE R+D  GRTY+V+H +R T W+RP P                      R  T +R  
Sbjct: 91  GWEARKDSQGRTYFVDHNTRTTTWERPQPLPAGWERRIDQHGRVYYVDHNTRTTTWQRPN 270

Query: 309 SEDVDGPDNRESPENWEIVREDENTEYSGQAVQSP----PSGHIDVQTHLAEEFNTRLAV 364
           +E V       +  NW+  R +   +   Q    P    PS   D    L + +  R   
Sbjct: 271 TEMV------TNWNNWQQWRNNRTMDAMNQRFLFPQTAQPSVDNDPLGPLLDGWEKRTDA 432

Query: 365 CGNPATSQPVTSSNHSSRGGSLQTCIFEEQPTLPVLLPTSSGLPPGWEEKQDDRGRSYYV 424
            G       V   NH +R     T  +E+  T  V+      L  GWE +    G  Y+V
Sbjct: 433 TGR------VYFVNHKNR-----TTQWEDPRTQGVMQ--EDPLQEGWEMRYTQEGVRYFV 573

Query: 425 DHNSKTTT 432
           DHN++TTT
Sbjct: 574 DHNTRTTT 597
>19738
          Length = 375

 Score = 79.0 bits (193), Expect = 8e-15,   Method: Composition-based stats.
 Identities = 36/78 (46%), Positives = 51/78 (65%)
 Frame = +2

Query: 701 ELKTGGSEIVVTNKNKKEYIYLVIQWRFVNRIQKQMAAFKEGFFELIPQDLIKIFDENEL 760
           EL  GG  I VTNKNK  Y+  + Q+R    +++++ +F  G  ELIP +L+ IFDE EL
Sbjct: 8   ELMPGGGNIRVTNKNKLSYLDCLAQYRLATSVKEEVESFLRGLNELIPDNLLSIFDEYEL 187

Query: 761 ELLMCGLGDVDVNDWREH 778
           ELLMCG+G   + D++ H
Sbjct: 188 ELLMCGMGTYSLADFKIH 241

 Score = 35.8 bits (81), Expect = 0.075,   Method: Compositional matrix adjust.
 Identities = 21/63 (33%), Positives = 29/63 (46%), Gaps = 9/63 (14%)
 Frame = +1

Query: 768 GDVDVNDWREHTKYKNGYSMNH---------QVIHWFWKAVWMMDSEKRIRLLQFVTGTS 818
           G VDV  W  H +       +H         +V+ WFW  +     E+  RLLQF TG S
Sbjct: 187 GVVDV--WHGHVQSGRLQDSSHRVRPJPSFNKVLDWFWTVIASFTEEQMARLLQFTTGCS 360

Query: 819 RVP 821
           ++P
Sbjct: 361 QLP 369
>29179
          Length = 1113

 Score = 64.7 bits (156), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 48/151 (31%), Positives = 73/151 (48%), Gaps = 5/151 (3%)
 Frame = -3

Query: 82  VKVIAGIGLAKKDILGASDPYVRVTLY-DPMSGILTSVQTKTIKKSLNPKWNEEILFRVL 140
           +++I  + L  KD+ G SDPYV++ L  D    +LT V+    K++LNP WNE  LF   
Sbjct: 487 LRIIRAVDLPAKDVTGTSDPYVKILLLPDKKHKLLTKVK----KRNLNPHWNECFLFEGW 320

Query: 141 PQ----RHRILFEVFDENRLTRDDFLGQVDVPLYPLPTENPRMERPYTFKDFVLHPRSHK 196
           P        +  +V D +R +RDD +G+  +PL     E    + P ++K   L P    
Sbjct: 319 PHNKLLEKTLYLQVIDYDRFSRDDPIGETYLPL----NEIDLSQSPVSWK--YLQPCKDT 158

Query: 197 SRVKGYLRLKMTYLPKNGSEDENADQAEELE 227
               G L L M Y PK+ S   +  + +  E
Sbjct: 157 RGKLGELLLSMCYQPKHWSSHRDRHEGQGTE 65
>05524
          Length = 2623

 Score = 52.0 bits (123), Expect(2) = 1e-09,   Method: Compositional matrix adjust.
 Identities = 36/126 (28%), Positives = 60/126 (47%), Gaps = 1/126 (0%)
 Frame = +2

Query: 763 LMCGLGDVDVNDWREHTKYKNGYSMNHQVIHWFWKAVWMMDSEKRIRLLQFVTGTSRVPM 822
           L CG  D+ +   +    YK G      ++ WFW+ +    + +R   L+FV G +R+P 
Sbjct: 485 LWCGSPDIPLTLLKSVATYK-GIEATAPLVQWFWEVMDEFSTAERSLFLRFVWGRTRLP- 658

Query: 823 NGFAELYGSNGPQSFTVEQWGTPDK-LPRAHTCFNRLDLPPYESFDELWDKLQMAIENTQ 881
              A+  G +      ++++  PD  LP ++TCF  L +P Y     L +KL+ AI   +
Sbjct: 659 RTIADFRGRDFVLQ-VLDKYNPPDHFLPESYTCFFLLKMPRYSDKLVLKEKLKYAIHFCK 835

Query: 882 GFDGVD 887
             D  D
Sbjct: 836 SIDTDD 853

 Score = 29.6 bits (65), Expect(2) = 1e-09,   Method: Compositional matrix adjust.
 Identities = 15/50 (30%), Positives = 27/50 (54%)
 Frame = +1

Query: 715 NKKEYIYLVIQWRFVNRIQKQMAAFKEGFFELIPQDLIKIFDENELELLM 764
           N+ +YI + I +R      +Q+   +EG   +IP  L+ +F   ELE ++
Sbjct: 346 NRADYIKMAINYRL-QEFDQQVRWVREGMSRVIPVPLLSLFTGLELETMV 492
>33148
          Length = 687

 Score = 50.1 bits (118), Expect = 4e-06,   Method: Composition-based stats.
 Identities = 31/93 (33%), Positives = 43/93 (46%)
 Frame = +3

Query: 792 IHWFWKAVWMMDSEKRIRLLQFVTGTSRVPMNGFAELYGSNGPQSFTVEQWGTPDKLPRA 851
           + +FW+A+    +E R R L+FVTG  R+P            P   +  +  T D LP +
Sbjct: 66  VKYFWEAMKAFSNEDRSRFLRFVTGRRRLP-----------APLVISTGKGDTIDSLPES 212

Query: 852 HTCFNRLDLPPYESFDELWDKLQMAIENTQGFD 884
            TC N L LP Y S     +KL+ A  N    D
Sbjct: 213 STCANMLYLPYYSSAKVAEEKLRYAAYNCIAID 311
>28454
          Length = 472

 Score = 43.5 bits (101), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 23/65 (35%), Positives = 35/65 (53%), Gaps = 3/65 (4%)
 Frame = -2

Query: 461 PLPPGWEERTHTDGRVFFINHNIKKTQWEDPRL--QNVAITGPAVPYSRDY-KRKYEFFR 517
           PLP GWE R  + GR+F+I+H  + T W+ P++  QNV          R    R+Y+  R
Sbjct: 306 PLPSGWEARVDSHGRIFYIDHMNRTTTWQRPQVGTQNVQRRPTLSSEQRQQLDRRYQSIR 127

Query: 518 RKLKK 522
           R + +
Sbjct: 126 RTITQ 112

 Score = 42.7 bits (99), Expect = 6e-04,   Method: Compositional matrix adjust.
 Identities = 16/32 (50%), Positives = 23/32 (71%)
 Frame = -2

Query: 407 LPPGWEEKQDDRGRSYYVDHNSKTTTWSKPTM 438
           LP GWE + D  GR +Y+DH ++TTTW +P +
Sbjct: 303 LPSGWEARVDSHGRIFYIDHMNRTTTWQRPQV 208

 Score = 36.6 bits (83), Expect = 0.051,   Method: Compositional matrix adjust.
 Identities = 14/27 (51%), Positives = 19/27 (70%)
 Frame = -2

Query: 254 GWEERQDVLGRTYYVNHESRRTQWKRP 280
           GWE R D  GR +Y++H +R T W+RP
Sbjct: 294 GWEARVDSHGRIFYIDHMNRTTTWQRP 214
>37652
          Length = 229

 Score = 42.7 bits (99), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 18/34 (52%), Positives = 21/34 (61%)
 Frame = -3

Query: 458 DLGPLPPGWEERTHTDGRVFFINHNIKKTQWEDP 491
           D   LP GWEER    GRV ++NH  + TQWE P
Sbjct: 107 DPNELPEGWEERRSASGRVHYVNHVTRTTQWETP 6

 Score = 41.2 bits (95), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 16/28 (57%), Positives = 21/28 (75%)
 Frame = -3

Query: 254 GWEERQDVLGRTYYVNHESRRTQWKRPS 281
           GWEER+   GR +YVNH +R TQW+ P+
Sbjct: 86  GWEERRSASGRVHYVNHVTRTTQWETPN 3

 Score = 38.9 bits (89), Expect = 0.009,   Method: Compositional matrix adjust.
 Identities = 15/30 (50%), Positives = 21/30 (70%)
 Frame = -3

Query: 407 LPPGWEEKQDDRGRSYYVDHNSKTTTWSKP 436
           LP GWEE++   GR +YV+H ++TT W  P
Sbjct: 95  LPEGWEERRSASGRVHYVNHVTRTTQWETP 6
>30322
          Length = 531

 Score = 38.9 bits (89), Expect = 0.009,   Method: Composition-based stats.
 Identities = 15/28 (53%), Positives = 21/28 (75%)
 Frame = +2

Query: 856 NRLDLPPYESFDELWDKLQMAIENTQGF 883
           NRLD+PPYE++++   KL  A+E T GF
Sbjct: 2   NRLDIPPYETYEKFLSKLTCAVEETCGF 85
>31463
          Length = 495

 Score = 38.9 bits (89), Expect = 0.009,   Method: Composition-based stats.
 Identities = 19/42 (45%), Positives = 24/42 (57%)
 Frame = +1

Query: 843 GTPDKLPRAHTCFNRLDLPPYESFDELWDKLQMAIENTQGFD 884
           G  D+LP A TC N L LP ++    L  KL  AIE+  GF+
Sbjct: 7   GQEDRLPTASTCMNLLKLPEFKDEKTLRTKLLYAIESGAGFE 132
>19350
          Length = 428

 Score = 38.5 bits (88), Expect = 0.011,   Method: Compositional matrix adjust.
 Identities = 19/69 (27%), Positives = 36/69 (52%)
 Frame = -3

Query: 608 NPNSGLCNEDHLSYFKFIGRVAGMAVYHGKLLDGFFIRPFYKMMLQKLITLHDMESVDSE 667
           +P +G    + L+ F+ +GR+ G+ +   ++   F  R   K +L + I+ HD+   D  
Sbjct: 222 SPRAGRNTPERLNAFRNVGRIMGLCLLQNEICPLFLNRHVLKYVLGRSISWHDLAFFDPV 43

Query: 668 YYSSLRWIL 676
            Y SLR ++
Sbjct: 42  MYESLRGLV 16
>01494
          Length = 2122

 Score = 38.1 bits (87), Expect = 0.017,   Method: Compositional matrix adjust.
 Identities = 27/95 (28%), Positives = 39/95 (41%), Gaps = 1/95 (1%)
 Frame = +1

Query: 84   VIAGIGLAKKDILGASDPYVRVTLYDPMSGILTSVQTKTIKKSLNPKWNEEILFRVL-PQ 142
             I G     K   G + P+V + +               +   LNP WNE  +F VL P+
Sbjct: 1174 TIVGARHLVKSGRGIASPFVEIEVTGXECDNQKFKTGTRVDNGLNPVWNENCVFDVLCPE 1353

Query: 143  RHRILFEVFDENRLTRDDFLGQVDVPLYPLPTENP 177
               + F V DE+     +FLGQ     +P+P   P
Sbjct: 1354 MALLRFAVMDEDIFGDPNFLGQAX---FPVPCIRP 1449
>07591
          Length = 796

 Score = 37.0 bits (84), Expect = 0.032,   Method: Compositional matrix adjust.
 Identities = 25/78 (32%), Positives = 38/78 (48%), Gaps = 4/78 (5%)
 Frame = +2

Query: 90  LAKKDILGASDPYVRVTLYDPMSGILTSVQTKTIKKSLNPKWNE-EILFRVLP---QRHR 145
           L KKD LG SDPY+ V             +T+ +K +LNP W   E+  + L     +  
Sbjct: 488 LDKKDFLGKSDPYLEVLRATSDGSWQMVHRTEVVKNNLNPSWRPFELSMQTLCGGNHQQN 667

Query: 146 ILFEVFDENRLTRDDFLG 163
           I F+V+D +     D++G
Sbjct: 668 IKFDVYDWDSDGSHDYIG 721

 Score = 34.7 bits (78), Expect = 0.16,   Method: Compositional matrix adjust.
 Identities = 25/98 (25%), Positives = 50/98 (51%), Gaps = 6/98 (6%)
 Frame = +2

Query: 89  GLAKKDILGASDPYVRVTLYDPMSGILTSV-QTKTIKKSLNPKWNEE-ILFRVLPQRHRI 146
           GL  KD+L  SDP     LY   +G      +T+ +K  L+P++    ++     +  ++
Sbjct: 89  GLLNKDVLSKSDPC--AVLYLHRAGHYEEFGRTENVKNCLDPRFARSFVMDYYFEEVQKL 262

Query: 147 LFEVFDENR----LTRDDFLGQVDVPLYPLPTENPRME 180
           +  V+D +     L+ DDFLG+++  L  + + +P ++
Sbjct: 263 MICVYDIDNTTPDLSDDDFLGKIETTLGQIVSNSPYIK 376
>13896
          Length = 827

 Score = 36.2 bits (82), Expect = 0.065,   Method: Compositional matrix adjust.
 Identities = 34/127 (26%), Positives = 56/127 (44%), Gaps = 1/127 (0%)
 Frame = +2

Query: 84  VIAGIGLAKKDILGASDPYVRVTLYDPMSGILTSVQTKTIKKSLNPKWNEEILFRVLPQR 143
           V+    L  K   G +D YV + L           QT TI+ + NP+W EE    +    
Sbjct: 170 VLRARNLISKGKSGNNDVYVTIQLGKE------KYQTSTIRNAHNPEWFEECDLPIPHLH 331

Query: 144 HRILFEVFDENRLTRDDFLGQVDVPLYPLPTENPRMERPYTFKDFVLHP-RSHKSRVKGY 202
             I   V+    L+ DDFLG   +PL+    E+    +  + K+    P R   ++ +G 
Sbjct: 332 SEIEVSVYHXGVLS-DDFLGYTSLPLWEQRLEDTTKTQWISLKN---KPNRGLDNKYRGE 499

Query: 203 LRLKMTY 209
           + +K+T+
Sbjct: 500 IEVKVTF 520
>22144
          Length = 634

 Score = 35.8 bits (81), Expect = 0.087,   Method: Compositional matrix adjust.
 Identities = 23/61 (37%), Positives = 31/61 (50%)
 Frame = -1

Query: 79  VVRVKVIAGIGLAKKDILGASDPYVRVTLYDPMSGILTSVQTKTIKKSLNPKWNEEILFR 138
           V +VKVI  IGL K+D  GA DPY  ++           V TK     ++P+W E  +F 
Sbjct: 397 VTQVKVIKAIGLQKQDAQGA-DPYCVISCEG------ERVTTKVEXNXVDPEWGEAAVFI 239

Query: 139 V 139
           V
Sbjct: 238 V 236
>14539
          Length = 436

 Score = 35.4 bits (80), Expect = 0.095,   Method: Composition-based stats.
 Identities = 19/52 (36%), Positives = 28/52 (53%), Gaps = 1/52 (1%)
 Frame = +3

Query: 123 IKKSLNPKWNEEILFRVL-PQRHRILFEVFDENRLTRDDFLGQVDVPLYPLP 173
           +   LNP WN+  +F VL P+   + F V DE+     +FLGQ     +P+P
Sbjct: 150 VDNGLNPVWNKNCVFDVLCPELALLRFAVMDEDTFGDPNFLGQ---GCFPVP 296
>25750
          Length = 428

 Score = 35.0 bits (79), Expect = 0.13,   Method: Compositional matrix adjust.
 Identities = 20/61 (32%), Positives = 33/61 (54%)
 Frame = +3

Query: 407 LPPGWEEKQDDRGRSYYVDHNSKTTTWSKPTMQDDPRSKIPAHLRGKTDSNDLGPLPPGW 466
           LP G+E+++  +G+ Y++   +  +TW  P +   PR      LR +    DLGP+  GW
Sbjct: 264 LPDGYEQRRTQQGQIYFLHTRTGVSTWHDPRV---PREASNLELRDE----DLGPMLHGW 422

Query: 467 E 467
           E
Sbjct: 423 E 425

 Score = 33.1 bits (74), Expect = 0.50,   Method: Compositional matrix adjust.
 Identities = 13/41 (31%), Positives = 24/41 (58%)
 Frame = +3

Query: 457 NDLGPLPPGWEERTHTDGRVFFINHNIKKTQWEDPRLQNVA 497
           +D+  LP G+E+R    G+++F++     + W DPR+   A
Sbjct: 249 HDMMELPDGYEQRRTQQGQIYFLHTRTGVSTWHDPRVPREA 371
>12851
          Length = 1291

 Score = 35.0 bits (79), Expect = 0.14,   Method: Compositional matrix adjust.
 Identities = 21/82 (25%), Positives = 36/82 (43%)
 Frame = +1

Query: 411 WEEKQDDRGRSYYVDHNSKTTTWSKPTMQDDPRSKIPAHLRGKTDSNDLGPLPPGWEERT 470
           W E +   GR+YY +  +K ++W KP             L+  T+     P    W+E  
Sbjct: 334 WGEFKAPDGRTYYYNSVTKKSSWEKPN-----------ELKSSTEXLSQCP----WKEYK 468

Query: 471 HTDGRVFFINHNIKKTQWEDPR 492
              G+V++ N   K++ W  P+
Sbjct: 469 SDSGKVYYHNSQTKESCWTKPK 534
>00178
          Length = 944

 Score = 34.7 bits (78), Expect = 0.16,   Method: Compositional matrix adjust.
 Identities = 16/44 (36%), Positives = 24/44 (54%), Gaps = 3/44 (6%)
 Frame = -3

Query: 453 KTDSNDLGPLPPG---WEERTHTDGRVFFINHNIKKTQWEDPRL 493
           K  S+ L P PP    W E  +TDGR ++ N    ++ WE P++
Sbjct: 180 KPPSSQLPPKPPEVLEWSEHKNTDGRSYYYNSRTMESTWEKPQV 49

 Score = 34.7 bits (78), Expect = 0.18,   Method: Compositional matrix adjust.
 Identities = 20/54 (37%), Positives = 28/54 (51%), Gaps = 6/54 (11%)
 Frame = -3

Query: 399 VLLPTSSGLPPG------WEEKQDDRGRSYYVDHNSKTTTWSKPTMQDDPRSKI 446
           V  P SS LPP       W E ++  GRSYY +  +  +TW KP +  D  +K+
Sbjct: 186 VQKPPSSQLPPKPPEVLEWSEHKNTDGRSYYYNSRTMESTWEKPQVLIDWEAKV 25
>30040
          Length = 652

 Score = 33.9 bits (76), Expect = 0.27,   Method: Composition-based stats.
 Identities = 22/71 (30%), Positives = 39/71 (54%), Gaps = 1/71 (1%)
 Frame = -3

Query: 98  ASDPYVRVTLYDPMSGILTSVQTKTIKK-SLNPKWNEEILFRVLPQRHRILFEVFDENRL 156
           ++DP+VRV+L   + G     +  ++++ S+NP WNE + F V  +   +L +V  E  +
Sbjct: 557 SADPFVRVSLL--VEGKKVKRKKTSVRRASINPVWNEALAFNVPAE---VLPKVTLEVSV 393

Query: 157 TRDDFLGQVDV 167
              D +G  DV
Sbjct: 392 LDHDLIGHGDV 360
>28393
          Length = 726

 Score = 31.2 bits (69), Expect = 1.7,   Method: Compositional matrix adjust.
 Identities = 17/52 (32%), Positives = 28/52 (53%)
 Frame = -3

Query: 79  VVRVKVIAGIGLAKKDILGASDPYVRVTLYDPMSGILTSVQTKTIKKSLNPK 130
           V +VKV+  +GL K+D+ GA DPY  ++           V T+    ++NP+
Sbjct: 136 VTQVKVVKAVGLEKQDVQGA-DPYCVISCEGE------KVSTRVESNTVNPE 2
>01656
          Length = 2498

 Score = 30.4 bits (67), Expect = 2.9,   Method: Compositional matrix adjust.
 Identities = 10/27 (37%), Positives = 21/27 (77%), Gaps = 1/27 (3%)
 Frame = +2

Query: 466 WEER-THTDGRVFFINHNIKKTQWEDP 491
           WE++ + + GR +++N + K++QWE+P
Sbjct: 2   WEQKVSRSTGRAYYLNIHTKESQWEEP 82
>06273
          Length = 1677

 Score = 29.6 bits (65), Expect = 5.9,   Method: Composition-based stats.
 Identities = 14/31 (45%), Positives = 19/31 (61%)
 Frame = -1

Query: 618 HLSYFKFIGRVAGMAVYHGKLLDGFFIRPFY 648
           HLSYF  +G V G+ VY G +   F +R +Y
Sbjct: 279 HLSYFPLVGXVXGVXVYLGGI---FAVRMWY 196
>18322
          Length = 501

 Score = 29.3 bits (64), Expect = 6.6,   Method: Composition-based stats.
 Identities = 13/42 (30%), Positives = 27/42 (64%)
 Frame = -1

Query: 124 KKSLNPKWNEEILFRVLPQRHRILFEVFDENRLTRDDFLGQV 165
           +++L PKWNE +   +      +  +VFD++ +++ DF+G+V
Sbjct: 390 EETLFPKWNELVTVEMKDDGSTLTIDVFDKDMISK-DFMGKV 268
>20379
          Length = 1354

 Score = 29.3 bits (64), Expect = 7.9,   Method: Compositional matrix adjust.
 Identities = 17/49 (34%), Positives = 25/49 (51%)
 Frame = +2

Query: 315 PDNRESPENWEIVREDENTEYSGQAVQSPPSGHIDVQTHLAEEFNTRLA 363
           P  +E+    E+  + +N E   + VQS   G I + TH AE+F   LA
Sbjct: 530 PATQETVHQEELADDVDNIEQFNENVQSDEIGAISLSTHEAEDFGEALA 676
>25445
          Length = 460

 Score = 28.9 bits (63), Expect = 8.4,   Method: Compositional matrix adjust.
 Identities = 12/23 (52%), Positives = 15/23 (65%)
 Frame = -1

Query: 118 VQTKTIKKSLNPKWNEEILFRVL 140
            +TKTIK SLNP+W+E      L
Sbjct: 73  TETKTIKSSLNPQWDETFTLTCL 5
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|124339838|ref|NP_038586.2| heat shock 70kDa protein
1-like [Mus musculus]
         (641 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

30255                                                                 308   e-106
21024                                                                 236   2e-62
37715                                                                 140   4e-53
27378                                                                 201   1e-51
26390                                                                 177   7e-45
24750                                                                 135   4e-32
31218                                                                  91   1e-18
06909                                                                  77   2e-18
09881                                                                  89   7e-18
20979                                                                  85   9e-17
12271                                                                  63   4e-10
13684                                                                  55   7e-08
03996                                                                  52   7e-07
34036                                                                  49   2e-06
13300                                                                  46   6e-05
>30255
          Length = 1761

 Score =  308 bits (788), Expect(2) = e-106,   Method: Compositional matrix adjust.
 Identities = 152/199 (76%), Positives = 165/199 (82%)
 Frame = -1

Query: 330  KAKIHDIVLVGGSTRIPKVQKLLQDYFNGRDLNKSINPDEXXXXXXXXXXXILMGDKSEK 389
            K  IH+IVLVGGSTRIPK+QKLLQD+FNG++L KSINPDE           IL GDKSE+
Sbjct: 1644 KPGIHEIVLVGGSTRIPKIQKLLQDFFNGKELCKSINPDEAVAYGACVQAAILHGDKSEE 1465

Query: 390  VQDXXXXXXXXXXXXXETAGGVMTVLIKRNSTIPTKQTQIFTTYSDNQPGVLIQVYEGER 449
            VQD             ETAGGVMT LIKRN+TIPTKQTQ FTTYSDNQPGVLIQVYEGER
Sbjct: 1464 VQDLLLLDVAPLSMGIETAGGVMTALIKRNTTIPTKQTQTFTTYSDNQPGVLIQVYEGER 1285

Query: 450  AMTRDNNLLGRFDLTGIPPAPRGVPQIEVTFDIDANGILNVTAMDKSTGKANKITITNDK 509
            AMTRDNNLLG+F+LTGIPPAPRGVPQIEVTFDIDANGILNV+A DKSTGK NKITITNDK
Sbjct: 1284 AMTRDNNLLGKFELTGIPPAPRGVPQIEVTFDIDANGILNVSAADKSTGKENKITITNDK 1105

Query: 510  GRLSKEEIERMVQEAERYK 528
            GRLSKEEIERMV +AE+ +
Sbjct: 1104 GRLSKEEIERMVNDAEKSR 1048

 Score = 96.7 bits (239), Expect(2) = e-106,   Method: Compositional matrix adjust.
 Identities = 45/79 (56%), Positives = 57/79 (72%)
 Frame = -3

Query: 537  KIAAKNALESYAFNMKSAVGDEGXXXXXXXXXXXXXXXXCNEVLSWLEANQLAEKDEFDH 596
            +I++KN+LESYAF+MKS + DE                 CNEV+SWL+ANQ AEKDE+D 
Sbjct: 1024 RISSKNSLESYAFHMKSTIEDEKIKDKIGEEDKKTIVDKCNEVISWLDANQTAEKDEYDD 845

Query: 597  KRKELENMCNPIITKLYQS 615
            K+KELE +CNPIITKLYQ+
Sbjct: 844  KQKELEKVCNPIITKLYQA 788
>21024
          Length = 3220

 Score =  236 bits (603), Expect = 2e-62,   Method: Compositional matrix adjust.
 Identities = 157/403 (38%), Positives = 224/403 (55%), Gaps = 17/403 (4%)
 Frame = +1

Query: 168  GLNVLRIINEPTAAAIA--YGL-----DKGSHGER----HVLIFDLGGGTFDVSILTIDD 216
            G NVLR+INEPTAAA+A  +G      D G    R    H+ + D  G        ++  
Sbjct: 727  G*NVLRVINEPTAAALALWHGQV*R*SDSGV*FRRRDV*HLYLGDPEG--------SV*S 882

Query: 217  GIFEVKATAGDTHLGGEDFDNRLVSHFVEEFKRKHKKDISQNKRAVRRLRTACERAKRTL 276
             I + +   G   L    +      +      RK K   SQ  + + R     +++K  L
Sbjct: 883  QINQRRHIPGRRGLLTTTWSTSWHQNL-----RKSKD*TSQRIQWLCRDYVRQQKSKIEL 1047

Query: 277  SSSTQANLEIDSLYEGID------FYTSITRARFEELCADLFRGTLEPVEKSLRDAKMDK 330
            SSS Q ++ +   Y  +D          ++R++FE L   L + T+ P +K+L+DA++ K
Sbjct: 1048 SSSLQTDINLP--YLTMDASGPKHMNLKLSRSKFESLVESLVKRTVGPCQKALQDAEVKK 1221

Query: 331  AKIHDIVLVGGSTRIPKVQKLLQDYFNGRDLNKSINPDEXXXXXXXXXXXILMGDKSEKV 390
            + I +++LVGG +R+PKVQ  +QD F GR  +KS+NPDE           +L GD    V
Sbjct: 1222 SDIGEVILVGGMSRMPKVQSTVQDLF-GRTPSKSVNPDEAVAIGAAIQGGVLAGD----V 1386

Query: 391  QDXXXXXXXXXXXXXETAGGVMTVLIKRNSTIPTKQTQIFTTYSDNQPGVLIQVYEGERA 450
             D             ET GGV T LI RN+TIPTK++Q+F+T +D Q  V I+V++GER 
Sbjct: 1387 TDVLLLDVTPLSLGIETLGGVFTKLINRNTTIPTKKSQVFSTAADGQTQVEIKVHQGERE 1566

Query: 451  MTRDNNLLGRFDLTGIPPAPRGVPQIEVTFDIDANGILNVTAMDKSTGKANKITITNDKG 510
            M  DN LLG+F L GIPPAPRGVPQ+EVTFDIDANGI+NV+A DK TGK  +I I +  G
Sbjct: 1567 MANDNKLLGQFTLVGIPPAPRGVPQVEVTFDIDANGIVNVSARDKGTGKEQQIVIQSSGG 1746

Query: 511  RLSKEEIERMVQEAERYKAEDEGQREKIAAKNALESYAFNMKS 553
             LSK+EIE M++ AE +  +D  ++E +   N  +S   + +S
Sbjct: 1747 -LSKDEIENMIKNAEAHAEDDRRKKELVEVLNQADSIIHDTES 1872

 Score =  182 bits (463), Expect = 2e-46,   Method: Compositional matrix adjust.
 Identities = 110/269 (40%), Positives = 158/269 (58%), Gaps = 2/269 (0%)
 Frame = +3

Query: 5   KGMAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFT-DTERLIGDAAKNQVAM 63
           KG  IGIDLGTT SCV + +  + +++ N +G+RTTPS +AFT D ER+ G  AK Q   
Sbjct: 243 KGHVIGIDLGTTNSCVALMEGKQAKVLENSEGSRTTPSVIAFTKDGERISGMPAKRQAVT 422

Query: 64  NPQNTVFDAKRLIGRKFNDPVVQSDMKLWPFQVINEAGKPKVMVSYKGEKKAFYPEEISS 123
           N +NT+   KRLIGR+F DP VQ DMK   ++++ +A      V  +G  K + P ++ +
Sbjct: 423 NAENTLSATKRLIGRRFEDPEVQKDMKNVSYKIV-KASNGDAWVEAQG--KMYSPSQVGA 593

Query: 124 MVLTKMKETAEAFLGHNVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAI 183
            VL KMKETAE++LG  V NAV+TVPAYFNDSQRQATKDAG I+GL  +       + + 
Sbjct: 594 FVLMKMKETAESYLGSKVNNAVVTVPAYFNDSQRQATKDAGQISGLKCVACDQRTHSCSS 773

Query: 184 AYGLDKGSHGERHVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGE-DFDNRLVSH 242
            +        +    +    G    +S  +  + +   + T  +TH   E  FDN +V+ 
Sbjct: 774 CFMAWTSLKIK**RCLI*AEGRLTSLSWRSRRECLKSNQPT--ETHSWEERTFDNYMVNF 947

Query: 243 FVEEFKRKHKKDISQNKRAVRRLRTACER 271
              EFK++   DI+++  AV+RLR A E+
Sbjct: 948 LASEFKKEQGLDITKDPMAVQRLREAAEK 1034
>37715
          Length = 468

 Score =  140 bits (354), Expect(2) = 4e-53,   Method: Compositional matrix adjust.
 Identities = 66/96 (68%), Positives = 78/96 (81%)
 Frame = -2

Query: 94  FQVINEAGKPKVMVSYKGEKKAFYPEEISSMVLTKMKETAEAFLGHNVTNAVITVPAYFN 153
            +VIN++ KP +     G  K F PEEIS+MVL KM++ AEA+LG  + NAV+TVPAYFN
Sbjct: 458 LKVINKSNKPHIQALVSGATKTFAPEEISAMVLGKMRDIAEAYLGKKIDNAVVTVPAYFN 279

Query: 154 DSQRQATKDAGVIAGLNVLRIINEPTAAAIAYGLDK 189
           D+QRQATKDAG IAGLNV+RIINEPTAAAIAYGLDK
Sbjct: 278 DAQRQATKDAGTIAGLNVMRIINEPTAAAIAYGLDK 171

 Score = 86.3 bits (212), Expect(2) = 4e-53,   Method: Composition-based stats.
 Identities = 36/52 (69%), Positives = 47/52 (90%)
 Frame = -1

Query: 196 HVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLVSHFVEEF 247
           ++L+FDLGGGTFDVS+LTID+G+FEV AT GDTHLGGEDFD R++ HF++ +
Sbjct: 156 NILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMDHFIKLY 1
>27378
          Length = 410

 Score =  201 bits (510), Expect = 1e-51,   Method: Compositional matrix adjust.
 Identities = 95/124 (76%), Positives = 107/124 (86%)
 Frame = -1

Query: 246 EFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQANLEIDSLYEGIDFYTSITRARFE 305
           EFKRK+KKD+  N RA+RRLRTA ERAKRTLSSST+A +E+D+L+EG DFYT I+RARFE
Sbjct: 410 EFKRKYKKDLRSNPRALRRLRTAAERAKRTLSSSTEATIEVDALFEGHDFYTKISRARFE 231

Query: 306 ELCADLFRGTLEPVEKSLRDAKMDKAKIHDIVLVGGSTRIPKVQKLLQDYFNGRDLNKSI 365
           ELCADLFR TL PVEK+L DAKMDK  IHDIVLVGGSTRIPKVQ LLQ +F G+ LN SI
Sbjct: 230 ELCADLFRQTLAPVEKALNDAKMDKQMIHDIVLVGGSTRIPKVQNLLQQFFGGKSLNLSI 51

Query: 366 NPDE 369
           NPDE
Sbjct: 50  NPDE 39
>26390
          Length = 665

 Score =  177 bits (450), Expect(2) = 7e-45,   Method: Compositional matrix adjust.
 Identities = 85/152 (55%), Positives = 108/152 (71%)
 Frame = +2

Query: 406 ETAGGVMTVLIKRNSTIPTKQTQIFTTYSDNQPGVLIQVYEGERAMTRDNNLLGRFDLTG 465
           ET GGVMT LI R +TIP ++ ++F+T  DNQ  V IQVYEGER+ T+DN+LLGRFDLTG
Sbjct: 56  ETVGGVMTTLIARGTTIPARKAKVFSTAQDNQDSVTIQVYEGERSRTKDNHLLGRFDLTG 235

Query: 466 IPPAPRGVPQIEVTFDIDANGILNVTAMDKSTGKANKITITNDKGRLSKEEIERMVQEAE 525
           IP APRGVPQIEVTF +DANG++ V+A DK TG+ N I I      LS E++ERMVQEA+
Sbjct: 236 IPAAPRGVPQIEVTFQVDANGVMQVSAEDKGTGQKNDIIIQQSGSGLSPEDVERMVQEAQ 415

Query: 526 RYKAEDEGQREKIAAKNALESYAFNMKSAVGD 557
            +  ED   RE   ++  LES A+  +  + D
Sbjct: 416 DFAEEDRKFRELTESRTGLESLAYTAQHQLQD 511

 Score = 21.9 bits (45), Expect(2) = 7e-45,   Method: Compositional matrix adjust.
 Identities = 8/23 (34%), Positives = 15/23 (65%)
 Frame = +3

Query: 580 LSWLEANQLAEKDEFDHKRKELE 602
           + WLEA+  A  +E D ++ +L+
Sbjct: 597 IQWLEAHPSASVEEVDERKSQLQ 665
>24750
          Length = 552

 Score =  135 bits (341), Expect = 4e-32,   Method: Compositional matrix adjust.
 Identities = 63/71 (88%), Positives = 69/71 (97%)
 Frame = +1

Query: 441 LIQVYEGERAMTRDNNLLGRFDLTGIPPAPRGVPQIEVTFDIDANGILNVTAMDKSTGKA 500
           ++QVYEGERAMTRDNNLLG+F+LTGIPPAPRGVPQIEVTFDIDANGILNV+A DKSTGK 
Sbjct: 154 MLQVYEGERAMTRDNNLLGKFELTGIPPAPRGVPQIEVTFDIDANGILNVSAADKSTGKE 333

Query: 501 NKITITNDKGR 511
           NKITITNDKG+
Sbjct: 334 NKITITNDKGQ 366
>31218
          Length = 322

 Score = 91.3 bits (225), Expect = 1e-18,   Method: Compositional matrix adjust.
 Identities = 47/100 (47%), Positives = 67/100 (67%)
 Frame = +2

Query: 227 DTHLGGEDFDNRLVSHFVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQANLEI 286
           DTHLGGEDFD RLV + V+  K+K  +D+  + RA+ RLR + E+AKR LSS     +++
Sbjct: 2   DTHLGGEDFDQRLVDYLVKLIKQKTGRDVRHDTRAMSRLRRSAEKAKRALSSQHSTKVDL 181

Query: 287 DSLYEGIDFYTSITRARFEELCADLFRGTLEPVEKSLRDA 326
           D +   +   T +TRA+FEEL  DLFR TL  V+++L D+
Sbjct: 182 DGVTSDLADLT-LTRAKFEELNTDLFRSTLTTVKRALEDS 298
>06909
          Length = 456

 Score = 77.4 bits (189), Expect(2) = 2e-18,   Method: Compositional matrix adjust.
 Identities = 34/67 (50%), Positives = 45/67 (67%)
 Frame = -3

Query: 549 FNMKSAVGDEGXXXXXXXXXXXXXXXXCNEVLSWLEANQLAEKDEFDHKRKELENMCNPI 608
            +MKS + DE                 C+EV++WL+ANQLAEKDE+D K+KE+E +CNPI
Sbjct: 388 LHMKSTIEDEKIKDKISTEDKKTILDKCDEVIAWLDANQLAEKDEYDDKQKEIEKVCNPI 209

Query: 609 ITKLYQS 615
           ITKLYQ+
Sbjct: 208 ITKLYQA 188

 Score = 33.9 bits (76), Expect(2) = 2e-18,   Method: Compositional matrix adjust.
 Identities = 14/23 (60%), Positives = 20/23 (86%)
 Frame = -1

Query: 526 RYKAEDEGQREKIAAKNALESYA 548
           +YK +DE Q+ +I+AKN+LESYA
Sbjct: 456 KYKEDDEKQKSRISAKNSLESYA 388
>09881
          Length = 600

 Score = 88.6 bits (218), Expect = 7e-18,   Method: Composition-based stats.
 Identities = 42/106 (39%), Positives = 64/106 (60%)
 Frame = +3

Query: 5   KGMAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMN 64
           K  A G+ LGT  +C+ V++ GK  + AND G+R+TP  VAFT  +  +G +AK  +  N
Sbjct: 177 KMAAYGVHLGTCSACLAVYKDGKTSVAANDAGDRSTPCVVAFTACDAEVGASAKQGIVSN 356

Query: 65  PQNTVFDAKRLIGRKFNDPVVQSDMKLWPFQVINEAGKPKVMVSYK 110
            +NTV + KR++G  F DPV Q  +   P +V+N+  +P   V +K
Sbjct: 357 VKNTVCNVKRILGLTFEDPVTQEYLASSPVKVVNQKNQPMFEVEFK 494

 Score = 47.0 bits (110), Expect = 2e-05,   Method: Composition-based stats.
 Identities = 25/50 (50%), Positives = 33/50 (66%)
 Frame = +2

Query: 138 GHNVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAYGL 187
           G  + +AV+ VP+ F+D QR A   A   AG  VLR+INE +AAA+AY L
Sbjct: 2   GKGIQDAVLAVPSDFSDKQRAAASAAASKAGFKVLRLINECSAAALAYDL 151
>20979
          Length = 976

 Score = 85.1 bits (209), Expect = 9e-17,   Method: Compositional matrix adjust.
 Identities = 46/140 (32%), Positives = 79/140 (56%), Gaps = 2/140 (1%)
 Frame = +1

Query: 232 GEDFDNRLVSHFVEEFKRKHKKD--ISQNKRAVRRLRTACERAKRTLSSSTQANLEIDSL 289
           G +   RL  H  + F  + K+   +  N RA+ +L    ER K+ LS+++    +++ L
Sbjct: 70  GVEMTLRLRDHLAKVFNGQKKRSFKLEDNPRAMAKLLKEAERVKKVLSANSDHKAQVEGL 249

Query: 290 YEGIDFYTSITRARFEELCADLFRGTLEPVEKSLRDAKMDKAKIHDIVLVGGSTRIPKVQ 349
            EG DF   ++R  + EL  DL     +P+E +L+ +++   +I +I+L+GG +R+P+VQ
Sbjct: 250 VEGEDFAAKVSREDYLELIKDLLARVTKPMEDALKVSEITMPEITEIILMGGGSRVPRVQ 429

Query: 350 KLLQDYFNGRDLNKSINPDE 369
           + L  +    DL KSIN DE
Sbjct: 430 EELLKFSGKSDLGKSINTDE 489
>12271
          Length = 1762

 Score = 62.8 bits (151), Expect = 4e-10,   Method: Compositional matrix adjust.
 Identities = 28/76 (36%), Positives = 48/76 (63%)
 Frame = +2

Query: 294 DFYTSITRARFEELCADLFRGTLEPVEKSLRDAKMDKAKIHDIVLVGGSTRIPKVQKLLQ 353
           DF   +TR ++  L  DL      PV++ L  +++  A+I +I+L+GG +R+PK+ ++L 
Sbjct: 41  DFSCKVTRDKYLHLIQDLLDRVTLPVQQVLTASQITWAEITEIILMGGGSRLPKIHEILL 220

Query: 354 DYFNGRDLNKSINPDE 369
           DY   ++L KS+N DE
Sbjct: 221 DYSGKKELGKSLNTDE 268
>13684
          Length = 438

 Score = 55.5 bits (132), Expect = 7e-08,   Method: Composition-based stats.
 Identities = 25/60 (41%), Positives = 37/60 (61%)
 Frame = -3

Query: 5   KGMAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMN 64
           K  A G+ LGT  +C+ V++ GK  + AND G+R+TP  VAFT  +  +G +AK  +  N
Sbjct: 181 KMAAYGVHLGTCSACLAVYKDGKTSVAANDAGDRSTPCVVAFTACDAEVGASAKQGIVSN 2
>03996
          Length = 1105

 Score = 52.0 bits (123), Expect = 7e-07,   Method: Compositional matrix adjust.
 Identities = 25/64 (39%), Positives = 41/64 (64%)
 Frame = -2

Query: 306  ELCADLFRGTLEPVEKSLRDAKMDKAKIHDIVLVGGSTRIPKVQKLLQDYFNGRDLNKSI 365
            EL  DL     +P+E +L+ +++   +I +I+L+GG +R+P+VQ+ L  +    DL KSI
Sbjct: 1056 ELIKDLLARVTKPMEDALKVSEITMPEITEIILMGGGSRVPRVQEELLKFSGKSDLGKSI 877

Query: 366  NPDE 369
            N DE
Sbjct: 876  NTDE 865
>34036
          Length = 363

 Score = 48.5 bits (114), Expect(2) = 2e-06,   Method: Composition-based stats.
 Identities = 19/26 (73%), Positives = 24/26 (92%)
 Frame = +2

Query: 590 EKDEFDHKRKELENMCNPIITKLYQS 615
           EKDE+D K+KE+E +CNPIITKLYQ+
Sbjct: 2   EKDEYDDKQKEIEKVCNPIITKLYQA 79

 Score = 21.6 bits (44), Expect(2) = 2e-06,   Method: Composition-based stats.
 Identities = 8/11 (72%), Positives = 9/11 (81%)
 Frame = +1

Query: 631 AATGPTIEEVD 641
            + GPTIEEVD
Sbjct: 145 GSAGPTIEEVD 177
>13300
          Length = 453

 Score = 45.8 bits (107), Expect = 6e-05,   Method: Compositional matrix adjust.
 Identities = 33/149 (22%), Positives = 69/149 (46%), Gaps = 17/149 (11%)
 Frame = +3

Query: 156 QRQATKDAGVIAGLNVLRIINEPTAAAIAYGLDKGSH---GERHVLIFDLGGGT-----F 207
           +R+A   A    G+NVL+++ +  A A+ YG+ +  +     ++ + +D+G  +      
Sbjct: 3   ERRAIMTAADXVGINVLQLMTDSAAVALNYGVFRRKNFNTTAQYYMFYDMGATSTVATVV 182

Query: 208 DVSILTIDDGI-------FEVKATAGDTHLGGEDFDNRLVSHFVEEFKRKHKKD--ISQN 258
              ++ + +G          +K    D  LGG +   RL  H  + F  + K+   +  N
Sbjct: 183 SYQVVKVKEGTRVESNPQLTIKGVGFDRTLGGLEMTLRLRDHLAKVFNGQKKRSFKLEDN 362

Query: 259 KRAVRRLRTACERAKRTLSSSTQANLEID 287
            RA+ +L    ER K+ LS+++    +++
Sbjct: 363 PRAMAKLLKEAERVKKVLSANSDHKAQVE 449
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|157041260|ref|NP_038539.2| erythrocyte protein band
4.1-like 2 [Mus musculus]
         (988 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

00990                                                                 384   e-106
11374                                                                 180   2e-45
18811                                                                 174   1e-43
17332                                                                 129   6e-30
13951                                                                  60   8e-19
28244                                                                  80   4e-15
08363                                                                  53   6e-07
05888                                                                  47   3e-05
03469                                                                  47   4e-05
17284                                                                  30   4.0  
>00990
          Length = 3161

 Score =  384 bits (986), Expect = e-106,   Method: Compositional matrix adjust.
 Identities = 182/328 (55%), Positives = 238/328 (72%), Gaps = 5/328 (1%)
 Frame = +3

Query: 219 DGTEYSCDLEKRAKGQVLFDRVCEHLNLLEKDYFGLLFQDH---PEQKNWLDPAKEIKRQ 275
           DG   + +L++ A+G+ LFD+VC+HL+L+EKDYFGL F D       K WL P K I +Q
Sbjct: 282 DGEHVNFELDRNAEGRELFDKVCQHLDLIEKDYFGLQFVDERISNHLKCWLSPDKRISKQ 461

Query: 276 LKNLPWLFTFNVKFYPPDPSQLTEDITRYFLCLQLRQDIASGRLPCSFVTHALLGSYTLQ 335
            K  PWLF F +KFYPPDP+QL E +TR+ + LQ R+DI SG+LP +++T A+LGSY +Q
Sbjct: 462 KKGGPWLFDFALKFYPPDPTQLRESLTRWLVVLQTRRDILSGKLPATYLTQAMLGSYCVQ 641

Query: 336 AEHGDYDPEEYDSID-LGDFQFAPAHTKELEEKVSELHKTHRGLSPAQADSQFLENAKRL 394
           A+ GDYDP E+  ++ + D  FAP  T +L EK+ ELH+ H+G +P +A++ FLENAK+L
Sbjct: 642 ADVGDYDPNEHRGVEYIRDTPFAPNQTIDLLEKIVELHRQHKGQTPDEAETNFLENAKKL 821

Query: 395 SMYGVDLHHAKDSEGVDIKLGVCANGLLIYKDRLRINRFAWPKILKISYKRSNFYIKVRP 454
           +MYGVDLH A+D   VDI LGVCA+GL +Y+++LRI+RF WPKILKISYKR  FYIKVRP
Sbjct: 822 AMYGVDLHAAQDVNNVDIMLGVCASGLQVYREKLRISRFVWPKILKISYKRRQFYIKVRP 1001

Query: 455 AELEQFESTIGFKLPNHRAAKRLWKVCVEHHTFYRLVSPEQPPKTK-FLTLGSKFRYSGR 513
           ++    E++  FKL  HR AKRLWK+CVEHH F+RL   EQ      F  LGSKFRYSGR
Sbjct: 1002SDNSAMENSFCFKLATHRLAKRLWKICVEHHAFFRLREAEQSQNAAMFPRLGSKFRYSGR 1181

Query: 514 TQAQTREASTLIDRPAPQFERASSKRVS 541
           T  QTR++S ++DRP P FER+   R S
Sbjct: 1182TLYQTRQSSQILDRPNPYFERSQPARSS 1265
>11374
          Length = 800

 Score =  180 bits (457), Expect = 2e-45,   Method: Compositional matrix adjust.
 Identities = 84/140 (60%), Positives = 100/140 (71%), Gaps = 1/140 (0%)
 Frame = +3

Query: 401 LHHAKDSEGVDIKLGVCANGLLIYKDRLRINRFAWPKILKISYKRSNFYIKVRPAELEQF 460
           LH A+D   VDI LGVCA+GL +Y+++LRI+RF WPKILKISYKR  FYIKVRP++    
Sbjct: 3   LHAAQDVNNVDIMLGVCASGLQVYREKLRISRFVWPKILKISYKRRQFYIKVRPSDNSAM 182

Query: 461 ESTIGFKLPNHRAAKRLWKVCVEHHTFYRLVSPEQPPKTK-FLTLGSKFRYSGRTQAQTR 519
           E++  FKL  HR AKRLWK+CVEHH F+RL   EQ      F  LGSKFRYSGRT  QTR
Sbjct: 183 ENSFCFKLATHRLAKRLWKICVEHHAFFRLREAEQSQNAAMFPRLGSKFRYSGRTLYQTR 362

Query: 520 EASTLIDRPAPQFERASSKR 539
            +S  +DRP P FER+   R
Sbjct: 363 HSSQTLDRPDPYFERSQPAR 422
>18811
          Length = 478

 Score =  174 bits (441), Expect = 1e-43,   Method: Compositional matrix adjust.
 Identities = 76/129 (58%), Positives = 101/129 (78%)
 Frame = -2

Query: 351 LGDFQFAPAHTKELEEKVSELHKTHRGLSPAQADSQFLENAKRLSMYGVDLHHAKDSEGV 410
           + D  FAP    EL EK+ ELH+ H+G +P +A+  +LENAK+LSMYGVDLH A+D   V
Sbjct: 387 IKDIPFAPNQAPELLEKIVELHRQHKGQTPDEAEVNYLENAKKLSMYGVDLHAAQDVNNV 208

Query: 411 DIKLGVCANGLLIYKDRLRINRFAWPKILKISYKRSNFYIKVRPAELEQFESTIGFKLPN 470
           DI LGVC++GL +Y+D+LRI+RF WPKI+KISYKR +FY+KVRPA+ +  E+++ F+LP 
Sbjct: 207 DIMLGVCSSGLQVYRDKLRISRFVWPKIIKISYKRKHFYVKVRPADNKGLETSVSFRLPT 28

Query: 471 HRAAKRLWK 479
           HR AKRLWK
Sbjct: 27  HRLAKRLWK 1
>17332
          Length = 473

 Score =  129 bits (324), Expect = 6e-30,   Method: Compositional matrix adjust.
 Identities = 69/157 (43%), Positives = 97/157 (61%), Gaps = 2/157 (1%)
 Frame = +2

Query: 219 DGTEYSCDLEKRAKGQVLFDRVCEHLNLLEKDYFGLLFQDHPEQKNWLDPAKEIKRQLKN 278
           D +++   ++   KG +L ++VCE LNL EKDYFGL F D   Q +WLD  K +  QLK 
Sbjct: 2   DDSDHQLQVKGNWKGILLQEKVCELLNLHEKDYFGLRFIDASGQTHWLDGNKSLSSQLKG 181

Query: 279 L--PWLFTFNVKFYPPDPSQLTEDITRYFLCLQLRQDIASGRLPCSFVTHALLGSYTLQA 336
              P    F VKFY  DP +L E+ITRY   LQ++QDI  GRLP +F   + L +Y +Q+
Sbjct: 182 CQTPHKLYFGVKFYAADPCKLREEITRYLFFLQVKQDILQGRLPVTFDEASELCAYAVQS 361

Query: 337 EHGDYDPEEYDSIDLGDFQFAPAHTKELEEKVSELHK 373
           E GD+DP ++    + +F F P  T+ELE +V+ LH+
Sbjct: 362 ELGDFDPRQHTDGYVSEFCFIPNQTEELERRVAGLHR 472
>13951
          Length = 720

 Score = 59.7 bits (143), Expect(2) = 8e-19,   Method: Compositional matrix adjust.
 Identities = 28/59 (47%), Positives = 39/59 (66%), Gaps = 3/59 (5%)
 Frame = -2

Query: 219 DGTEYSCDLEKRAKGQVLFDRVCEHLNLLEKDYFGLLFQDH---PEQKNWLDPAKEIKR 274
           DG   + +L++ A+G+ LFD+VC+HL+L+EKDYFGL F D       K WL P K I +
Sbjct: 368 DGEHVNFELDRNAEGRELFDKVCQHLDLIEKDYFGLQFVDERISNHLKCWLSPDKRISK 192

 Score = 53.1 bits (126), Expect(2) = 8e-19,   Method: Composition-based stats.
 Identities = 20/41 (48%), Positives = 29/41 (70%)
 Frame = -1

Query: 270 KEIKRQLKNLPWLFTFNVKFYPPDPSQLTEDITRYFLCLQL 310
           K+ + + K  PWLF F +KFYPPDP+QL E +TR+ + L +
Sbjct: 204 KDFQNRKKGGPWLFDFALKFYPPDPTQLRESLTRWLVVLHV 82
>28244
          Length = 422

 Score = 80.1 bits (196), Expect = 4e-15,   Method: Composition-based stats.
 Identities = 47/124 (37%), Positives = 69/124 (55%), Gaps = 4/124 (3%)
 Frame = -1

Query: 422 LIYKDRLRINRFAWPKILKISYKRSNF-YIKVRPAELEQFESTIG-FKLPNHRAAKRLWK 479
           L+++   +I  F WPK+ ++ +K      + V   E  Q +  I  F+L + +A K LWK
Sbjct: 422 LVFEGNXKIGLFFWPKMTRLDFKGKKLTLVAVEDDENGQSQDHIFVFRLQSEKACKHLWK 243

Query: 480 VCVEHHTFYRLVSPEQPPKTK--FLTLGSKFRYSGRTQAQTREASTLIDRPAPQFERASS 537
             VEHH F+RL  P Q P  +  F  +GS+FRYSGRT+ QT   +    R + +FER  S
Sbjct: 242 CAVEHHAFFRLKGPVQGPNARQNFFRMGSRFRYSGRTEYQTSTMNRA--RRSVKFERKPS 69

Query: 538 KRVS 541
           +R S
Sbjct: 68  QRYS 57
>08363
          Length = 1878

 Score = 53.1 bits (126), Expect = 6e-07,   Method: Compositional matrix adjust.
 Identities = 39/124 (31%), Positives = 55/124 (44%), Gaps = 1/124 (0%)
 Frame = +1

Query: 852 EPPVVKTEMVTISDASQRTEISTKEVPIVQTETKTITYESPQIDGGAGGDSGVLLXXXXX 911
           +PP V TE V      +   + TK VP+V+TET+T+TYE         G+ GVL+     
Sbjct: 112 DPPTVATESVHYQPDVEEVPVPTKNVPLVKTETRTVTYEREGF--PFDGEDGVLVSASSH 285

Query: 912 XXXXXXXXXXXXXXXXVKGGISETRIEKRIVITGXXXX-XXXXXXXXXIREAREQHPDMS 970
                            K G+ ETR+E R+V++               IR   E +PDMS
Sbjct: 286 STRMQTIETTTYKTE--KDGVQETRVEHRVVLSSTDDDFDYDAALADAIRSVTEFNPDMS 459

Query: 971 VTRV 974
           V R+
Sbjct: 460 VERI 471
>05888
          Length = 490

 Score = 47.4 bits (111), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 22/36 (61%), Positives = 25/36 (69%)
 Frame = -2

Query: 504 LGSKFRYSGRTQAQTREASTLIDRPAPQFERASSKR 539
           LGSKFRYSGRT  Q R +S  +DRP P FER+   R
Sbjct: 489 LGSKFRYSGRTLYQARHSSQTLDRPDPYFERSQPAR 382
>03469
          Length = 1275

 Score = 46.6 bits (109), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 33/104 (31%), Positives = 47/104 (45%), Gaps = 1/104 (0%)
 Frame = -3

Query: 872  ISTKEVPIVQTETKTITYESPQIDGGAGGDSGVLLXXXXXXXXXXXXXXXXXXXXXVKGG 931
            + TK VP+V+TET+T+TYE         G+ GVL+                      K G
Sbjct: 1258 VPTKNVPLVKTETRTVTYEREGF--PFDGEDGVLVSASSHSTRMQTIETTTYKTE--KDG 1091

Query: 932  ISETRIEKRIVITGXXXX-XXXXXXXXXIREAREQHPDMSVTRV 974
            + ETR+E R+V++               IR   E +PDMSV R+
Sbjct: 1090 VQETRVEHRVVLSSTDDDFDYDAALADAIRSVTEFNPDMSVERI 959
>17284
          Length = 489

 Score = 30.4 bits (67), Expect = 4.0,   Method: Composition-based stats.
 Identities = 12/29 (41%), Positives = 19/29 (65%)
 Frame = +3

Query: 414 LGVCANGLLIYKDRLRINRFAWPKILKIS 442
           L VC N  ++ K  L+I++  WPK+L +S
Sbjct: 75  LNVCLNSCVL*K*ILKIDKLRWPKVLTVS 161
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|176866245|ref|NP_291030.2| solute carrier family 4,
sodium bicarbonate cotransporter-like, member 10 [Mus musculus]
         (1088 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

14939                                                                 211   e-106
17976                                                                 184   3e-54
18083                                                                 132   9e-31
00560                                                                  33   0.75 
36201                                                                  31   2.2  
>14939
          Length = 1186

 Score =  211 bits (538), Expect(2) = e-106,   Method: Compositional matrix adjust.
 Identities = 108/218 (49%), Positives = 151/218 (69%), Gaps = 8/218 (3%)
 Frame = -3

Query: 866  APGEQPKFLGIREQRVTGLMIFILMGSSVFMTSILKFIPMPVLYGVFLYMGASSLKGIQL 925
             PGEQPKFLG+REQRVTG+ IF+L+G SV +TS+LKFIPMPVLYGVFLYMG SSL+G+QL
Sbjct: 683  CPGEQPKFLGVREQRVTGITIFLLIGISVMLTSVLKFIPMPVLYGVFLYMGVSSLRGMQL 504

Query: 926  FDRIKLFWMPAKHQPDFIYLRHVPLRKVHLFTVIQMSCLGLLWIIK-VSRAAIVFPMMVL 984
              R+ +++MPAK+Q D ++LRHV   +VHLFT+IQ+ CL  LW IK   + +I FP+MVL
Sbjct: 503  VHRVLIWFMPAKYQWDLMFLRHVRTNRVHLFTIIQIFCLLCLWGIKSYKKISIAFPIMVL 324

Query: 985  ALVFVRKLMDFLFTKRELSWLDDLMPXXXXXXXXXXXXXXXQSMLAMEDEGTVQLPLE-G 1043
            A+ FVRK +D++F +REL WLDD+MP               +   ++  EG+  +PL  G
Sbjct: 323  AMCFVRKALDWVFDQRELKWLDDIMPEAHKRAKEDEIKKQEEQRFSL-IEGSTSIPLAMG 147

Query: 1044 HYRDDPSV------INISDEMSKTAMWGNLLVTADNSK 1075
               +  ++      +NIS+EMS+TA+W +++    +S 
Sbjct: 146  LNMEHITIQAEMDQVNISEEMSRTALWKSIMHNESSSN 33

 Score =  193 bits (490), Expect(2) = e-106,   Method: Compositional matrix adjust.
 Identities = 88/150 (58%), Positives = 107/150 (71%)
 Frame = -1

Query: 722  FPTKVRSIVSDFAVFLTILCMVLIDYAIGIPSPKLQVPSVFKPTRDDRGWFVTPLGPNPW 781
            FPT VR+ +SDF+V + IL MV+ D  +G+P+PKL VP  F PT   RGW + P+G NPW
Sbjct: 1114 FPTMVRATLSDFSVLIAILSMVVFDICVGLPTPKLHVPETFAPTNPKRGWLINPVGENPW 935

Query: 782  WTXXXXXXXXXXXXXXXFMDQQITAVIINRKEHKLKKGCGYHLDLLMVAVMLGVCSIMGL 841
            WT               FMDQQITAVI+NRKE+KL KG GYHLDL +V+V++ +CS +GL
Sbjct: 934  WTTLAAVIPALLAVILIFMDQQITAVIVNRKENKLVKGRGYHLDLFIVSVLIILCSFLGL 755

Query: 842  PWFVAATVLSITHVNSLKLESECSAPGEQP 871
            PWFVAATVLSI HVNSLK ES+CSAP   P
Sbjct: 754  PWFVAATVLSINHVNSLKKESQCSAPANNP 665
>17976
          Length = 781

 Score =  184 bits (466), Expect(2) = 3e-54,   Method: Compositional matrix adjust.
 Identities = 84/137 (61%), Positives = 109/137 (79%), Gaps = 1/137 (0%)
 Frame = +1

Query: 875  GIREQRVTGLMIFILMGSSVFMTSILKFIPMPVLYGVFLYMGASSLKGIQLFDRIKLFWM 934
            G+REQR+TGLM+ +L G +V  T++LKFIPM VLYGVFLYMG ++LKG+Q  DRI L   
Sbjct: 139  GVREQRLTGLMVGLLSGLTVLFTAVLKFIPMAVLYGVFLYMGMAALKGMQFIDRILLMLK 318

Query: 935  PAKHQPDFIYLRHVPLRKVHLFTVIQMSCLGLLWIIK-VSRAAIVFPMMVLALVFVRKLM 993
            PAK+QPD  YLRHVP+++VH+FT IQ+ CL +LW+IK V   +I+FP+MVL   FVRK +
Sbjct: 319  PAKYQPDTTYLRHVPIKRVHIFTAIQVVCLAVLWVIKSVKSVSIIFPIMVLGTCFVRKGL 498

Query: 994  DFLFTKRELSWLDDLMP 1010
            D+LFT+ EL WLDD+MP
Sbjct: 499  DYLFTQGELKWLDDIMP 549

 Score = 47.4 bits (111), Expect(2) = 3e-54,   Method: Compositional matrix adjust.
 Identities = 24/37 (64%), Positives = 29/37 (78%), Gaps = 1/37 (2%)
 Frame = +3

Query: 840 GLP-WFVAATVLSITHVNSLKLESECSAPGEQPKFLG 875
           GLP   VAATV ++ H+ SLK ESEC+APGE+P FLG
Sbjct: 30  GLPLGTVAATVSALAHIMSLKKESECTAPGERPTFLG 140
>18083
          Length = 865

 Score =  132 bits (332), Expect = 9e-31,   Method: Composition-based stats.
 Identities = 75/199 (37%), Positives = 120/199 (60%), Gaps = 4/199 (2%)
 Frame = -3

Query: 799 FMDQQITAVIINRKEHKLKKGCGYHLDLLMVAVMLGVCSIMGLPWFVAATVLSITHVNSL 858
           FMDQ I+A ++N  ++K+KKG  YH DLL++AV+  V S+   P   AA   S  HV +L
Sbjct: 854 FMDQNISAALVNAPQNKMKKGTAYHWDLLVIAVVNAVISVFAFPMVHAALPHSPLHVRAL 675

Query: 859 KLESECSAPGEQPK-FLGIREQRVTGLMIFILMGSSVFMTSILKFIPMPVLYGVFLYMGA 917
               E    G   +  + +RE R+T ++  IL+G S+ +  +L +IP PVLYG+FLY+  
Sbjct: 674 ADVEERVVQGHITQTVVRVRETRITAILSHILIGLSILIMFVLAYIPTPVLYGLFLYVAI 495

Query: 918 SSLKGIQLFDRIKLFWMPAKHQPDFIYLRHVPLRKVHLFTVIQMSCLGLLWI---IKVSR 974
           ++L   Q+F+RI LF+      P   Y+RHVP RKVH+FT+IQ+  L +L +   +  + 
Sbjct: 494 TALYDNQMFERITLFFTEQSAYPPTHYIRHVPQRKVHIFTLIQLLQLVVLCVFGFVSFAY 315

Query: 975 AAIVFPMMVLALVFVRKLM 993
             + FP+++  L+ +R ++
Sbjct: 314 LKMFFPVLIFLLIPIRHMV 258
>00560
          Length = 886

 Score = 32.7 bits (73), Expect = 0.75,   Method: Composition-based stats.
 Identities = 28/115 (24%), Positives = 47/115 (40%), Gaps = 3/115 (2%)
 Frame = +3

Query: 877 REQRVTGLMIFILMGSSVFMTSILKFIPMPVLYGVFLYMGASSLKGIQLFDRIKLFWMPA 936
           ++QR+ G    ILMG+  F  + L ++PM +L      M   +L  + +       W P 
Sbjct: 216 KKQRIVGFFTCILMGTFCFSVASL-YLPMLLLKARKFAM-LYTLGSLFVISSFAFLWGPY 389

Query: 937 KHQPDFIYLRHVPLRKVH---LFTVIQMSCLGLLWIIKVSRAAIVFPMMVLALVF 988
            H      +  +P   V+   +F  I  S    +WI       I     ++ALV+
Sbjct: 390 NHLKHLFSMSRLPFTIVYFGTMFATIYFS----MWIHSTVLTVICALGQIIALVW 542
>36201
          Length = 571

 Score = 31.2 bits (69), Expect = 2.2,   Method: Composition-based stats.
 Identities = 26/87 (29%), Positives = 40/87 (45%), Gaps = 1/87 (1%)
 Frame = +3

Query: 457 ILDIKRKAPFFWSDFRDAFSLQCLASFLFLYCACMSPVITFGGL-LGEATEGRISAIESL 515
           IL +KR  P    +F   F ++C  +F+    A  +  + F  L LG A++GR+  +E L
Sbjct: 171 ILSLKR*RPA*GENF---FPVKCSVNFII---AMAAXTVXFSPLCLGXASKGRVGGLEML 332

Query: 516 FGASMTGIAYSLFGGQPLTILGSTGPV 542
             A   G+A          + G T PV
Sbjct: 333 VDADXPGVA---------QLAGDTAPV 386
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|225690606|ref|NP_778190.3| calcium-transporting
ATPase 2C1 [Mus musculus]
         (918 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

06342                                                                 382   e-106
00499                                                                 239   5e-63
36566                                                                 211   8e-55
26683                                                                 127   2e-29
30333                                                                 113   3e-25
12151                                                                  87   1e-22
28890                                                                  83   6e-16
29829                                                                  81   2e-15
14773                                                                  75   2e-13
08160                                                                  71   2e-12
04985                                                                  64   3e-10
14321                                                                  55   1e-07
13525                                                                  40   0.004
07486                                                                  39   0.009
21541                                                                  38   0.020
17925                                                                  37   0.044
33697                                                                  36   0.057
>06342
          Length = 2428

 Score =  382 bits (981), Expect = e-106,   Method: Compositional matrix adjust.
 Identities = 253/691 (36%), Positives = 365/691 (52%), Gaps = 74/691 (10%)
 Frame = +2

Query: 155 LVPGDTVCLSVGDRVPADLRLFE--AVDLSVDESSLTGETAPCSKVTAPQPAANGDLASR 212
           LVPGD V +SVGD+VPAD+R+ +  +  L +D++ LTGE+    K T P P        +
Sbjct: 5   LVPGDIVEVSVGDKVPADIRILKIHSTTLRIDQAILTGESVSVMKHTDPIPDPRAVNQDK 184

Query: 213 SNIAFMGTLVRCGKAKGIVIGTGENSEFGEVFKMMQAEEAPKTPLQKSMDLLGKQLSFYS 272
            N+ F GT V  GK KG+VIGTG  +E G++   M   E  KTPLQ+ +D    QLS   
Sbjct: 185 KNLLFSGTNVAAGKCKGLVIGTGLTTEIGKIRNEMMDTEQEKTPLQQKLDEFSNQLS--- 355

Query: 273 FGIIGIIMLVGWLLG--------------KDILEMFTISVSLAVAAIPEGLPIVVTVTLA 318
             +I II +  W +               K  +  F I+V+LAVAAIPEGLP V+T  LA
Sbjct: 356 -KVITIICIAVWAINIGHFNDPAHGGSWIKGAIYYFKIAVALAVAAIPEGLPAVITTCLA 532

Query: 319 LGVMRMVKKRAIVKKLPIVETLGCCNVICSDKTGTLTKNEMTVTHILTSDGLHA------ 372
           LG  RM KK AIV+ LP VETLGC +VICSDKTGTLT N+M+V  +     +        
Sbjct: 533 LGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCKLFIFSQIDTNQIKTT 712

Query: 373 --EVTGVGYNQFGEVIVDGDVVHGFYNPAVSRIVEAGCVCNDAVIRNNTL------MGKP 424
             EVTG  Y   GE+  +G  V     P +  +     +CND+ +  N        +G+ 
Sbjct: 713 QFEVTGSTYAPDGELYQNGKKVKASDYPGLEELCTICGMCNDSSVDYNEAKTQYEKVGEA 892

Query: 425 TEGALIALAMKMGLDGLQQDYIRKAE------------------YPFSSEQKWMAVKCVH 466
           TE AL  LA K+      +  + K E                    FS ++K M+V CV 
Sbjct: 893 TETALTVLAEKLNFYNTDKSSLNKREMGTVCNHVIQDMWRKEFTLEFSRDRKSMSVFCVP 1072

Query: 467 RTQQDRP--EICFMKGAYEQVIKYCTTYNSKGQTLALTQQQRDLYQQEKARMGSA--GLR 522
                 P     F KGA E ++  CT        + ++   ++   +     G+    LR
Sbjct: 1073NKPTRVPGGARMFAKGAPEGLLDRCTHVRIGNNKVPMSPAIKNEIMKLTKIYGTGRDTLR 1252

Query: 523 VLALAS--GPELGQ----------------LTFLGLVGIIDPPRTGVKEAVTTLIASGVS 564
            LALA+   P   +                +TF+G+VG++DPPR  V  ++    A+G+ 
Sbjct: 1253CLALATIDNPPRREDMDLEDSRKFIEYETNMTFVGVVGMLDPPREEVMASIKNCRAAGIR 1432

Query: 565 IKMITGDSQETAIAIASRLGLYSKTSQS----VSGEEVDTMEVQHLSQIVPKVAVFYRAS 620
           + +ITGD++ TA AI  R+G++S++  +     +G E D +  +     V +  +F R  
Sbjct: 1433VIVITGDNKATAEAICRRIGVFSESENTEGLAYTGREFDELPPEDQRAAVMRARLFARVE 1612

Query: 621 PRHKMKIIKSLQKNGAVVAMTGDGVNDAVALKAADIGVAMGQTGTDVCKEAADMILVDDD 680
           P HK KI++ LQ  G + AMTGDGVNDA ALK A+IG+AMG +GT V K A++M+L DD+
Sbjct: 1613PAHKSKIVEYLQAEGEISAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKSASEMVLADDN 1789

Query: 681 FQTIMSAIEEGKGIYNNIKNFVRFQXXXXXXXXXXXXXXXXMNFPNPLNAMQILWINIIM 740
           F TI++A+EEG+ IYNN+K F+R+                 +  P  L  +Q+LW+N++ 
Sbjct: 1790FSTIVAAVEEGRAIYNNMKQFIRYLISSNIGEVVCIFLTAALGIPEALIPVQLLWVNLVT 1969

Query: 741 DGPPAQSLGVEPVDKDVIRKPPRNWKDSILT 771
           DG PA +LG  P D D+++KPPRN ++ ++T
Sbjct: 1970DGFPATALGFNPPDLDIMQKPPRNPREGLIT 2062
>00499
          Length = 4026

 Score =  239 bits (609), Expect = 5e-63,   Method: Compositional matrix adjust.
 Identities = 174/524 (33%), Positives = 253/524 (48%), Gaps = 67/524 (12%)
 Frame = +2

Query: 308 GLPIVVTVTLALGVMRMVKKRAIVKKLPIVETLGCCNVICSDKTGTLTKNEMTVTHILTS 367
           GL   VTV L L   RM +K  +VK L  VETLG  + ICSDKTGTLT+N MTV H+   
Sbjct: 2   GLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMW-- 175

Query: 368 DGLHAEVTGVGYNQFGEVIVDGDVVHGFYNPAVSR-------IVEAGCVCNDAVIRNNT- 419
                         F   IV+ D      N   SR       +     +CN A  + N  
Sbjct: 176 --------------FDGRIVEADTSDDQSNATYSRSDPTWMALSRVAMLCNRAEFKGNQD 313

Query: 420 --------LMGKPTEGALIALAMKMGLDGLQQDYIRK----AEYPFSSEQKWMAVKCVHR 467
                     G  +E AL+   +++ + G   +Y R+     E PF+S  K+     +H 
Sbjct: 314 NVPILKRECNGDASESALLK-CVELSI-GHVTEYRRRNEKIVEIPFNSSNKYQV--SIHE 481

Query: 468 TQQ-DRPE-ICFMKGAYEQVIKYCTTYNSKGQTLALTQQQRDLYQQEKARMGSAGLRVLA 525
           T+  D P  +  MKGA E+++  C+T    G+   L    R+ +      +G  G RVL 
Sbjct: 482 TEDPDDPRYLLVMKGAPERIMDRCSTILLNGKEQPLDDNFREAFNAAYLELGGLGERVLG 661

Query: 526 LAS-----------------GPE--LGQLTFLGLVGIIDPPRTGVKEAVTTLIASGVSIK 566
                               GP   +  L F+GL+ +IDPPR  V +AV    ++G+ + 
Sbjct: 662 FCDYFLPVDQFPPGYEFDPEGPNFPITGLRFVGLMAMIDPPRAAVPDAVGKCRSAGIKVI 841

Query: 567 MITGDSQETAIAIASRLGLYSKTSQSVSG---------EEVDTMEVQ-------HLSQIV 610
           M+TGD   TA AIA  +G+ S+ S++V           EEVD  E +        L  + 
Sbjct: 842 MVTGDHPITAKAIARGVGIISEGSKTVEDIASERGIPVEEVDPREAKAAVIHGGDLRDMT 1021

Query: 611 P----------KVAVFYRASPRHKMKIIKSLQKNGAVVAMTGDGVNDAVALKAADIGVAM 660
           P             VF R SP+ K+ I++  Q+ G +VA+TGDGVND+ ALK ADIGVAM
Sbjct: 1022PAQIDEILRNHSEIVFARTSPQQKLIIVEGCQRQGQIVAVTGDGVNDSPALKKADIGVAM 1201

Query: 661 GQTGTDVCKEAADMILVDDDFQTIMSAIEEGKGIYNNIKNFVRFQXXXXXXXXXXXXXXX 720
           G  G+DV K+AADMIL+DD+F +I++ +EEG+ I++N+K  + +                
Sbjct: 1202GIAGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEISPFLLFI 1381

Query: 721 XMNFPNPLNAMQILWINIIMDGPPAQSLGVEPVDKDVIRKPPRN 764
             + P PL  + IL I++  D  PA SL  E  + D++++ PR+
Sbjct: 1382LADIPLPLGTITILCIDLGTDMVPAISLAYEKAENDIMKRQPRD 1513
>36566
          Length = 589

 Score =  211 bits (538), Expect = 8e-55,   Method: Compositional matrix adjust.
 Identities = 100/162 (61%), Positives = 118/162 (72%)
 Frame = +3

Query: 629 KSLQKNGAVVAMTGDGVNDAVALKAADIGVAMGQTGTDVCKEAADMILVDDDFQTIMSAI 688
           + LQ+NG VV MTGDGVNDAVALK+A+IG++MG +GTDV KEA+DMILVDDDF TI++AI
Sbjct: 102 RRLQQNGLVVGMTGDGVNDAVALKSAEIGISMGVSGTDVSKEASDMILVDDDFTTILNAI 281

Query: 689 EEGKGIYNNIKNFVRFQXXXXXXXXXXXXXXXXMNFPNPLNAMQILWINIIMDGPPAQSL 748
           EEGKGI+ NI+NFVRFQ                +  PNPLNAMQILWINIIMDGPPAQSL
Sbjct: 282 EEGKGIFYNIRNFVRFQLSTSIAALSLIAVSTLLRLPNPLNAMQILWINIIMDGPPAQSL 461

Query: 749 GVEPVDKDVIRKPPRNWKDSILTKNXXXXXXXXXXXXXCGTL 790
           GVEPVD DVI++PPR+  D I+T+               GTL
Sbjct: 462 GVEPVDHDVIKQPPRHVGDPIITRRLIINVLSSALIIVSGTL 587
>26683
          Length = 397

 Score =  127 bits (319), Expect = 2e-29,   Method: Compositional matrix adjust.
 Identities = 64/101 (63%), Positives = 71/101 (70%)
 Frame = +2

Query: 803 TPRDTTMTFTCFVFFDMFNALSSRSQTKSVFEIGLCSNKMFCYAVLGSIMGQLLVIYFPP 862
           T RDTTMTFTCFVFFDMFNALS RSQTKSVF IGL +N+MF  AV  SI+GQ+LV+YFPP
Sbjct: 5   TKRDTTMTFTCFVFFDMFNALSCRSQTKSVFTIGLTTNRMFLLAVAFSIIGQMLVVYFPP 184

Query: 863 LQKVFQTEXXXXXXXXXXXXXXXXVCIVSEIIKKVERSREK 903
           LQ VFQTE                V +VSEI K  ERS E+
Sbjct: 185 LQMVFQTEALTAYDILFLVTLTSSVLVVSEIKKWFERSLER 307
>30333
          Length = 386

 Score =  113 bits (283), Expect = 3e-25,   Method: Composition-based stats.
 Identities = 57/95 (60%), Positives = 64/95 (67%)
 Frame = +2

Query: 809 MTFTCFVFFDMFNALSSRSQTKSVFEIGLCSNKMFCYAVLGSIMGQLLVIYFPPLQKVFQ 868
           MTFTCFVFFDMFNAL SRSQ KSV +IGL SNK+F  AV GS++GQLLVIYFPPLQ +FQ
Sbjct: 2   MTFTCFVFFDMFNALGSRSQAKSVLQIGLLSNKVFVLAVGGSLVGQLLVIYFPPLQAIFQ 181

Query: 869 TEXXXXXXXXXXXXXXXXVCIVSEIIKKVERSREK 903
           TE                V I SEI K   R+ E+
Sbjct: 182 TEALYASDLVFLVCLTSTVFIFSEIRKWFSRTHER 286
>12151
          Length = 880

 Score = 87.0 bits (214), Expect(2) = 1e-22,   Method: Compositional matrix adjust.
 Identities = 55/188 (29%), Positives = 92/188 (48%), Gaps = 13/188 (6%)
 Frame = +3

Query: 652 KAADIGVAMGQTGTDVCKEAADMILVDDDFQTIMSAIEEGKGIYNNIKNFVRFQXXXXXX 711
           + AD+G AMG +GTDV KEA+D+IL DD+F +I+ A+  G+ +Y++I  F++FQ      
Sbjct: 288 QKADVGFAMGISGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSIAKFLQFQLTVNVV 467

Query: 712 XXXXXXXXXXMNFPNPLNAMQILWINIIMDGPPAQSLGVEPVDKDVIRKPPRNWKDSILT 771
                         +PL A+Q+LW+N+IMD   + +L  E    +++++ P      +++
Sbjct: 468 AVFVAFVGACSIGDSPLKAIQMLWVNLIMDTLASLALATELPSSELLKRRPYGRTKPLIS 647

Query: 772 KNXXXXXXXXXXXXXCGTLFVF-------W--RELRDNVITPRDT----TMTFTCFVFFD 818
           K                 L +        W  R    +  TPR T    T+ F  FV   
Sbjct: 648 KTMWKNILGHAFYQILVILLLLFQGAKAVWDRRWHPTSRETPRPTNQHFTIIFNAFVMMT 827

Query: 819 MFNALSSR 826
           +FN +++R
Sbjct: 828 LFNEVNAR 851

 Score = 38.5 bits (88), Expect(2) = 1e-22,   Method: Composition-based stats.
 Identities = 28/97 (28%), Positives = 48/97 (49%), Gaps = 15/97 (15%)
 Frame = +1

Query: 571 DSQETAIAIASRLGLYSKTSQSV--SGEEVDTM--------EVQHLSQIVPKVAVFYRAS 620
           D+  TA +IAS+ G+       +   G+E + +          + + ++ P + V  R+S
Sbjct: 1   DNVNTARSIASKCGIIQPGDDGLVLEGKEFNQLIRDAEGEISQEKVDEVWPNLRVLARSS 180

Query: 621 PRHKMKIIKSL-----QKNGAVVAMTGDGVNDAVALK 652
           P+ K  ++K +       +  VVA+TGDG ND  ALK
Sbjct: 181 PQDKYILVKHIIDSKVSTSREVVAVTGDGTNDGPALK 291
>28890
          Length = 552

 Score = 82.8 bits (203), Expect = 6e-16,   Method: Compositional matrix adjust.
 Identities = 60/172 (34%), Positives = 83/172 (48%), Gaps = 6/172 (3%)
 Frame = -3

Query: 120 QEYRSEKSLEELSKLVPPECHCVREGKLEHTLARDLVPGDTVCLSVGDRVPADLRLFEAV 179
           QE +S K ++    LVP     VR  +     A +LV GD V    GDRVPADLR+  A 
Sbjct: 526 QEAKSSKIMDSFKNLVPQFAVVVRGDQKLSVKAEELVVGDIVECKFGDRVPADLRVISAH 347

Query: 180 DLSVDESSLTGETAPCSKVTAPQPAANGDLASRSNIAFMGTLVRCGKAKGIVIGTGENSE 239
              VD SSLTGE+ P S+  + +      L +R NI F  T    G  +GIVI TG+++ 
Sbjct: 346 GFKVDNSSLTGESEPQSR--SAEFTHENPLETR-NICFFSTNAVEGTCRGIVIKTGDDTV 176

Query: 240 FGEVFKMMQAEEAPKTPLQKS----MDLLGKQLSFY--SFGIIGIIMLVGWL 285
            G +  +    E   TP+ K     + ++     F   SF +I  I+   WL
Sbjct: 175 MGRIANLASGLEVGDTPIAKEIAHFIHIITGVAVFLGVSFFVIAFILGYFWL 20
>29829
          Length = 465

 Score = 80.9 bits (198), Expect = 2e-15,   Method: Compositional matrix adjust.
 Identities = 39/117 (33%), Positives = 68/117 (58%)
 Frame = -3

Query: 656 IGVAMGQTGTDVCKEAADMILVDDDFQTIMSAIEEGKGIYNNIKNFVRFQXXXXXXXXXX 715
           +G AMG +GTDV KEA+D+IL DD+F +I+ A+  G+ +Y++I  F++FQ          
Sbjct: 460 LGFAMGISGTDVAKEASDIILTDDNFTSIVKAVXWGRNVYDSIAKFLQFQLTVNVVAVFV 281

Query: 716 XXXXXXMNFPNPLNAMQILWINIIMDGPPAQSLGVEPVDKDVIRKPPRNWKDSILTK 772
                     +PL A+Q+LW+N+IMD   + +L  E    +++++ P      +++K
Sbjct: 280 AFVGACSIGDSPLEAIQMLWVNLIMDTLASLALATELPSNELLKRKPYGRTKPLISK 110
>14773
          Length = 794

 Score = 74.7 bits (182), Expect = 2e-13,   Method: Compositional matrix adjust.
 Identities = 36/108 (33%), Positives = 62/108 (57%)
 Frame = +2

Query: 665 TDVCKEAADMILVDDDFQTIMSAIEEGKGIYNNIKNFVRFQXXXXXXXXXXXXXXXXMNF 724
           +DV K+AADMIL+DD+F +I++ +EEG+ I++N+K  + +                    
Sbjct: 2   SDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEISPFLVYILFGT 181

Query: 725 PNPLNAMQILWINIIMDGPPAQSLGVEPVDKDVIRKPPRNWKDSILTK 772
           P PL  + IL+I++  D  PA SL  E  + D++++PPR   D ++ +
Sbjct: 182 PLPLGVITILFIDLGTDMVPAISLAYEMAESDIMKRPPRTISDRLVNE 325
>08160
          Length = 459

 Score = 71.2 bits (173), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 57/168 (33%), Positives = 75/168 (44%), Gaps = 20/168 (11%)
 Frame = +2

Query: 308 GLPIVVTVTLALGVMRMVKKRAIVKKLPIVETLGCCNVICSDKTGTLTKNEMTVTHILTS 367
           GL   VTV L L   RM +K  +VK L  VETLG  + ICSDKTGTLT+N MTV H+   
Sbjct: 2   GLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMW-- 175

Query: 368 DGLHAEVTGVGYNQFGEVIVDGDVVHGFYNPAVSR-------IVEAGCVCNDAVIRNNT- 419
                         F   IV+ D      N   SR       +   G +CN A  + N  
Sbjct: 176 --------------FDGRIVEADTSDDQSNATYSRTDVTWMALARVGMLCNRAEFKGNQD 313

Query: 420 --------LMGKPTEGALIALAMKMGLDGLQQDYIRK----AEYPFSS 455
                     G  +E AL+  A+++ + G   +Y R+     E PF+S
Sbjct: 314 NVPILKRECNGDASESALLK-AVELSI-GQVTEYRRRNKKIVEIPFNS 451
>04985
          Length = 1671

 Score = 63.5 bits (153), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 45/164 (27%), Positives = 75/164 (45%), Gaps = 5/164 (3%)
 Frame = -1

Query: 604  QHLSQIVPKV----AVFYRASPRHKMKIIKSLQKNGAVVAMTGDGVNDAVALKAADIGVA 659
             H  +++PKV     VF R +P  K  +I++LQ    +V M GDG ND  ALKAA  G++
Sbjct: 1653 NHFPELLPKVCTQGTVFARMAPDQKCALIENLQSYDYIVGMCGDGANDCEALKAAHAGIS 1474

Query: 660  MGQTGTDVCKEAADMILVDDDFQTIMSAIEEGKGIYNNIKNFVRFQXXXXXXXXXXXXXX 719
            + +    V       I   ++ + +++A+ EG+     + +F  F+              
Sbjct: 1473 LSEAEASVAAPFTSRI---NNIECVVTAMREGRAAL--VTSFGCFKYMALYSFIQFISVL 1309

Query: 720  XXMNFPNPLNAMQILWINIIMDGPPAQSLGVE-PVDKDVIRKPP 762
                    L+ ++ L+I++I+    A  LG     DK V  KPP
Sbjct: 1308 ILYTCQTNLSDLEFLYIDLIITTTIAVLLGYTGAYDKLVRHKPP 1177
>14321
          Length = 568

 Score = 55.1 bits (131), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 31/82 (37%), Positives = 44/82 (53%), Gaps = 3/82 (3%)
 Frame = +2

Query: 582 RLGLYSKTSQSVSGEEVDTMEVQH---LSQIVPKVAVFYRASPRHKMKIIKSLQKNGAVV 638
           R  +  K    ++GE +  ++  H   L  ++P   VF R +P+ K  II  L+  G V 
Sbjct: 158 RKSIIPKYDLCLTGESLTFLQSDHPKLLRLLLPNTRVFARVAPKQKELIITVLKAQGFVT 337

Query: 639 AMTGDGVNDAVALKAADIGVAM 660
            M GDG ND  ALK AD+GVA+
Sbjct: 338 LMCGDGTNDVGALKHADVGVAL 403
>13525
          Length = 645

 Score = 40.0 bits (92), Expect = 0.004,   Method: Composition-based stats.
 Identities = 19/34 (55%), Positives = 22/34 (64%)
 Frame = +2

Query: 319 LGVMRMVKKRAIVKKLPIVETLGCCNVICSDKTG 352
           L   RM +K  +VK L  VETLG  + ICSDKTG
Sbjct: 2   LTAKRMARKNCLVKNLEAVETLGSTSTICSDKTG 103
>07486
          Length = 763

 Score = 38.9 bits (89), Expect = 0.009,   Method: Compositional matrix adjust.
 Identities = 20/40 (50%), Positives = 29/40 (72%)
 Frame = -1

Query: 650 ALKAADIGVAMGQTGTDVCKEAADMILVDDDFQTIMSAIE 689
           AL  AD+G+A+G TGTDV  EAAD++L+  D   + +AI+
Sbjct: 742 ALAQADVGIAIG-TGTDVAVEAADIVLMKSDLVDVYAAIK 626
>21541
          Length = 445

 Score = 37.7 bits (86), Expect = 0.020,   Method: Composition-based stats.
 Identities = 26/108 (24%), Positives = 45/108 (41%)
 Frame = +3

Query: 142 VREGKLEHTLARDLVPGDTVCLSVGDRVPADLRLFEAVDLSVDESSLTGETAPCSKVTAP 201
           +R G+L      +++ G+   +  GD +PAD  + ++ DL      +     PC K    
Sbjct: 135 IRNGELHQIPVGEILVGEICQIKYGDLLPADGVIIQSNDLKNRREFVNRRVGPCEKGRGQ 314

Query: 202 QPAANGDLASRSNIAFMGTLVRCGKAKGIVIGTGENSEFGEVFKMMQA 249
            P            AF+      G+ K +V   G NS+ G +F ++ A
Sbjct: 315 GPH-----------AFVRHPCNGGQWKMVVTAVGVNSQTGIIFALLGA 425
>17925
          Length = 510

 Score = 36.6 bits (83), Expect = 0.044,   Method: Compositional matrix adjust.
 Identities = 17/53 (32%), Positives = 32/53 (60%), Gaps = 2/53 (3%)
 Frame = +3

Query: 593 VSGEEVDTMEVQHLSQIVPKVA--VFYRASPRHKMKIIKSLQKNGAVVAMTGD 643
           + G ++  M+ + +  I+      VF R SP+ K+ I++  Q+NG +VA+TG+
Sbjct: 336 IHGGDLKNMDAKDIDDILHNFVEIVFARTSPQQKLIIVEGCQRNGQIVAVTGE 494
>33697
          Length = 310

 Score = 36.2 bits (82), Expect = 0.057,   Method: Composition-based stats.
 Identities = 19/53 (35%), Positives = 27/53 (50%)
 Frame = -2

Query: 543 IIDPPRTGVKEAVTTLIASGVSIKMITGDSQETAIAIASRLGLYSKTSQSVSG 595
           +IDPPR  V +AV    ++G+ + M+TGD   T+     R G Y    Q   G
Sbjct: 201 MIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITSQGHRQRGGDYLGGQQDSGG 43
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6754900|ref|NP_035981.1| 5' nucleotidase, ecto [Mus
musculus]
         (576 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

19065                                                                 381   e-106
29237                                                                 106   3e-23
18163                                                                  96   3e-20
18141                                                                  72   8e-13
34373                                                                  36   0.046
06432                                                                  33   0.39 
18153                                                                  28   7.5  
>19065
          Length = 1859

 Score =  381 bits (979), Expect = e-106,   Method: Compositional matrix adjust.
 Identities = 202/438 (46%), Positives = 283/438 (64%), Gaps = 3/438 (0%)
 Frame = +1

Query: 116 ALGNHEFDNGVEGLIDPLLRNVKFPILSANIKARGPLAHQISGLFLPSKVLSVGGEVVGI 175
            LGNHEFD G  G +D  L   +FP+LS+N+ A   L H I      S ++ +GG+ VGI
Sbjct: 529 GLGNHEFDLGETG-VDEFLSLAQFPVLSSNLNA-SQLPH-IESRVKRSVIVQIGGQAVGI 699

Query: 176 VGYTSKETPFLSNPGTNLVFEDEISALQPEVDKLKTLNVNKIIALGHSGFEMDKLIAQKV 235
           VGYT+ +T  +S PG  L F DE+ A++ EV KL +  V K++ +GH+GF  D +IA+ V
Sbjct: 700 VGYTTTDTAIISKPG-RLTFSDEVEAVRSEVTKLTSQGVTKVVCVGHAGFMTDLMIARNV 876

Query: 236 RGVDIVVGGHSNTFLYTGNPPSKEVPAGKYPFIVTADDGRQVPVVQAYAFGKYLGYLKVE 295
            GVD+VVGGH+NTFLYTG  P  E P G YP +V  +DG +  VVQ YAFGKYLG+L+VE
Sbjct: 877 SGVDVVVGGHTNTFLYTGTAPGHEEPEGDYPQVVEREDGSRALVVQDYAFGKYLGFLQVE 1056

Query: 296 FDDKGNVITSYGNPILLNSSIPEDATIKADINQWRIKLDNYSTQELGRTIVYLDGSTQTC 355
           FDD G V +  GNPILL++S+P DA ++ ++ +WR  ++  + Q +G T+V L G    C
Sbjct: 1057FDDAGQVTSWSGNPILLDNSVPRDAAMQTELAKWRAGVEEMAQQVVGSTLVQLVGEPSVC 1236

Query: 356 RFRECNMGNLICDAMINNNLRHPDEMFWNHVSMCIVNGGGIRSPIDEKNNGTITWENLAA 415
           R  ECN+GNLI DAM+  NLRH D + WNHV++ I NGGGIR  +   + G IT  ++ +
Sbjct: 1237RMGECNLGNLITDAMVVQNLRHSDSVEWNHVAIAIFNGGGIRYSV---SKGDITVADVLS 1407

Query: 416 VLPFGGTFDLVQLKGSTLKKAFEHSVHRYG--QSTGEFLQVGGIHVVYDINRKPWNRVVQ 473
           V PF  + D+V+L G+ L    EHS   +   +  G FLQ  G+HVVY++++    RV  
Sbjct: 1408VSPFRNSIDIVELNGTALWAVMEHSASLWDPLEHQGGFLQHSGLHVVYNMSQPKGQRVXS 1587

Query: 474 LEVLCTKCRVPIYEPLEMDKVYKVTLPSYLANGGDGFQMIKDELLKHD-SGDQDISVVSE 532
           ++V C  C VP  E LE+ KVYKV +P++L  GGDG+ +I D ++KH  +GD D  V++E
Sbjct: 1588IKVKCADCEVPQMEGLELSKVYKVVVPNFLVVGGDGYNVIADNMIKHHLNGDLDTDVITE 1767

Query: 533 YISKMKVVYPAVEGRIKF 550
           Y+ K   +   +EGRI+F
Sbjct: 1768YVKKFSPITQGLEGRIRF 1821
>29237
          Length = 419

 Score =  106 bits (264), Expect = 3e-23,   Method: Compositional matrix adjust.
 Identities = 53/140 (37%), Positives = 82/140 (58%), Gaps = 1/140 (0%)
 Frame = +1

Query: 303 ITSY-GNPILLNSSIPEDATIKADINQWRIKLDNYSTQELGRTIVYLDGSTQTCRFRECN 361
           I SY G P L ++S+ +D      +  WR  ++    Q +G+++V L+G    CR RECN
Sbjct: 1   IVSYEGKPHLQDASVAQDNATLEKLQPWREGIEGMRNQTVGQSLVRLEGDRTVCRRRECN 180

Query: 362 MGNLICDAMINNNLRHPDEMFWNHVSMCIVNGGGIRSPIDEKNNGTITWENLAAVLPFGG 421
           MGN++ D M+  NLR  +   W+ VS+ I N GGIR  I     GTIT+ ++ +V PFG 
Sbjct: 181 MGNVLSDGMLYYNLRKGNSSGWSEVSIAISNAGGIRESI---QTGTITYGDVLSVQPFGN 351

Query: 422 TFDLVQLKGSTLKKAFEHSV 441
             D ++++G  LK+AF  ++
Sbjct: 352 KIDAIRIEGRYLKQAFXSAL 411
>18163
          Length = 477

 Score = 96.3 bits (238), Expect = 3e-20,   Method: Compositional matrix adjust.
 Identities = 53/140 (37%), Positives = 78/140 (55%), Gaps = 2/140 (1%)
 Frame = -3

Query: 341 LGRTIVYLDGSTQTCRFRECNMGNLICDAMINNN-LRHPDEMFWNHVSMCIVNGGGIRSP 399
           +G T V L+G +  CR RECN+GNLI D+M++   L +    +W    + ++ GGGIR+ 
Sbjct: 418 VGYTKVKLEGGS-ICRRRECNLGNLIADSMVHTRVLEYKGGDYWTDAPIALLQGGGIRTT 242

Query: 400 IDEKNNGTITWENLAAVLPFGGTFDLVQLKGSTLKKAFEHSVHRYG-QSTGEFLQVGGIH 458
           ID+  NG+IT  ++  VLP+     + ++ G TL+ A E S    G  S G FLQ+ GI 
Sbjct: 241 IDKNLNGSITGSDILTVLPYENNLYVTRISGKTLRNALERSAFVRGTDSDGGFLQLAGIR 62

Query: 459 VVYDINRKPWNRVVQLEVLC 478
           V YD  +    +V    V C
Sbjct: 61  VEYDYGKAAGQQVTSALVRC 2
>18141
          Length = 433

 Score = 71.6 bits (174), Expect = 8e-13,   Method: Compositional matrix adjust.
 Identities = 39/115 (33%), Positives = 66/115 (57%), Gaps = 1/115 (0%)
 Frame = -2

Query: 461 YDINRKPWNRVVQLEVLCTKCRVPIYEPLEMDKVYKVTLPSYLANGGDGFQMIKDELLKH 520
           Y++ +    RVV L+ LCT C+VP ++P+E + VYKV L +++  GGDG+ + +++  ++
Sbjct: 429 YNLAKPDGQRVVSLKALCTDCQVPEFKPVEDNTVYKVILSNFVYKGGDGYTVFREKSTEY 250

Query: 521 -DSGDQDISVVSEYISKMKVVYPAVEGRIKFSAASHYQGSFPLVILSFWAMILIL 574
            + GD D  V   YI     +Y AVE RI+F   +    S   +  +   ++LIL
Sbjct: 249 INLGDLDSDVFIHYIRDYSPLYTAVEERIQFVHDNCDSTSLASLPCALRPLLLIL 85
>34373
          Length = 668

 Score = 35.8 bits (81), Expect = 0.046,   Method: Compositional matrix adjust.
 Identities = 28/68 (41%), Positives = 37/68 (54%), Gaps = 6/68 (8%)
 Frame = +2

Query: 505 NGGDGFQMIKD-ELLKHDSGDQDISVVSEYISKMKVVYPAVEGRI-----KFSAASHYQG 558
           NGGDG+++I+D E         D    S+Y+     VYP +E RI     K SAAS + G
Sbjct: 5   NGGDGYKLIEDKEPFSELMLLNDQFAFSKYLEARHYVYPEIEDRIVMHEPKNSAASIF-G 181

Query: 559 SFPLVILS 566
           S  LV+LS
Sbjct: 182 SIVLVMLS 205
>06432
          Length = 1334

 Score = 32.7 bits (73), Expect = 0.39,   Method: Compositional matrix adjust.
 Identities = 14/54 (25%), Positives = 29/54 (53%), Gaps = 1/54 (1%)
 Frame = -3

Query: 462  DINRKPWNRVVQLEVLCTKCRVPI-YEPLEMDKVYKVTLPSYLANGGDGFQMIK 514
            D  ++ WNRV+ + +LC   R+ I + P +  +++K+           GFQ+++
Sbjct: 1083 DFRQEIWNRVISVSMLCVNYRLNIDFFPFQFSRIFKLCFRLV-----SGFQLLE 937
>18153
          Length = 1018

 Score = 28.5 bits (62), Expect = 7.5,   Method: Compositional matrix adjust.
 Identities = 15/46 (32%), Positives = 24/46 (52%), Gaps = 1/46 (2%)
 Frame = -1

Query: 458 HVVYDINRKPWNRVVQLEVLCTKC-RVPIYEPLEMDKVYKVTLPSY 502
           H +Y IN + WN+ +++        RV  +EP+E+D V      SY
Sbjct: 352 HGLYQINHQLWNKRIEIYSHSLLLYRVVYFEPVELDSV*SAATLSY 215
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6755863|ref|NP_035761.1| tumor rejection antigen gp96
[Mus musculus]
         (802 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

01628                                                                 381   e-106
11278                                                                 376   e-104
15623                                                                 197   2e-55
27487                                                                 104   1e-22
25874                                                                  70   4e-12
>01628
          Length = 2109

 Score =  381 bits (979), Expect = e-106,   Method: Compositional matrix adjust.
 Identities = 189/417 (45%), Positives = 276/417 (66%), Gaps = 1/417 (0%)
 Frame = -3

Query: 334  ELMNDIKPIWQRPSKEVEEDEYKAFYKSFSKESDDPMAYIHFTAEGEVTFKSILFVPTSA 393
            E +N  KP+W R   ++  +EY  FYKS + + +D +A  HF+ EG++ F+++LF+P  A
Sbjct: 1957 EELNKTKPLWTRNPDDITAEEYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPKRA 1778

Query: 394  PRGLFDEYGSKKSDYIKLYVRRVFITDDFHDMMPKYLNFVKGVVDSDDLPLNVSRETLQQ 453
            P  +F+    K +  IKLYVRRVFI D+  D++P+YLNFVKGVVDS+DLPLN+SRE LQQ
Sbjct: 1777 PFDMFENKKKKNN--IKLYVRRVFIMDNCEDIIPEYLNFVKGVVDSEDLPLNISREMLQQ 1604

Query: 454  HXXXXXXXXXXXXXXXDMIKKIADEKYN-DTFWKEFGTNIKLGVIEDHSNRTRLAKLLRF 512
                            ++I  +A++K N + F+++F  N+KLG+ ED +NR +++  LR+
Sbjct: 1603 SKILKVIRKNLVKKCMELIDDLAEDKDNYNKFYEQFAKNLKLGIHEDSTNRKKISDFLRY 1424

Query: 513  QSSHHSTDITSLDQYVERMKEKQDKIYFMAGSSRKEAESSPFVERLLKKGYEVIYLTEPV 572
             SS  + ++ +  +YV RMK+ Q  IY++ G +R+  ++S FVER+ K+G+EV+Y+ +P+
Sbjct: 1423 HSSQSADEMVTFKEYVSRMKDNQKDIYYITGETREAVQNSAFVERVKKRGFEVLYMVDPI 1244

Query: 573  DEYCIQALPEFDGKRFQNVAKEGVKFDESEKTKESREATEKEFEPLLNWMKDKALKDKIE 632
            DEYC+Q L E+DGK    V KEG++  E E  K+  E  + EFE L   MK+  L  K+E
Sbjct: 1243 DEYCVQQLKEYDGKNLVCVTKEGLELPEDEAEKKKFEEAKAEFEGLCKAMKE-ILDKKVE 1067

Query: 633  KAVVSQRLTESPCALVASQYGWSGNMERIMKAQAYQTGKDISTNYYASQKKTFEINPRHP 692
            K  VSQRL  SPC +V SQYGWS NMERIMKAQA    +D ST  Y + KK FEINP HP
Sbjct: 1066 KVTVSQRLVSSPCCIVTSQYGWSANMERIMKAQAL---RDTSTMGYMAAKKHFEINPDHP 896

Query: 693  LIRDMLRRIKEDEDDKTVMDLAVVLFETATLRSGYLLPDTKAYGDRIERMLRLSLNI 749
            +++ +  +   D++DK+V DL ++LFETA L SG+ L D  ++ +RI RM++L L I
Sbjct: 895  IVKTLKVKCDADKNDKSVKDLCMLLFETALLSSGFTLEDPTSHANRIHRMVKLGLGI 725
>11278
          Length = 988

 Score =  376 bits (966), Expect = e-104,   Method: Compositional matrix adjust.
 Identities = 184/250 (73%), Positives = 216/250 (86%)
 Frame = +1

Query: 35  LGKSREGSRTDDEVVQREEEAIQLDGLNASQIRELREKSEKFAFQAEVNRMMKLIINSLY 94
           LGKS E SRTDDE VQ+EEEAI+LDGLN +Q++ELREKSEKFAFQAEVNRMMKLIINSLY
Sbjct: 142 LGKSMEASRTDDETVQKEEEAIKLDGLNVAQMKELREKSEKFAFQAEVNRMMKLIINSLY 321

Query: 95  KNKEIFLRELISNASDALDKIRLISLTDENALAGNEELTVKIKCDKEKNLLHVTDTGVGM 154
           KNKEIFLRELISNASDALDKIR +SLT+++ L   +EL++KIK D E ++LHVTDTG+GM
Sbjct: 322 KNKEIFLRELISNASDALDKIRFMSLTNKDVLHATDELSIKIKADTENHVLHVTDTGIGM 501

Query: 155 TREELVKNLGTIAKSGTSEFLNKMTEAQEDGQSTSELIGQFGVGFYSAFLVADKVIVTSK 214
           T  +LVKNLGTIAKSGTS+FL KM EA       ++LIGQFGVGFYS+FLVAD+V+VTSK
Sbjct: 502 TYNDLVKNLGTIAKSGTSDFLAKMGEASP--TELNDLIGQFGVGFYSSFLVADRVVVTSK 675

Query: 215 HNNDTQHIWESDSNEFSVIADPRGNTLGRGTTITLVLKEEASDYLELDTIKNLVRKYSQF 274
           HN+D Q++WESD+  FSV  DPRGNTLGRGTTI+L LKEEA D+LE  T+ +LV+KYSQF
Sbjct: 676 HNDDEQYVWESDAESFSVAKDPRGNTLGRGTTISLHLKEEAHDFLEAGTLTSLVKKYSQF 855

Query: 275 INFPIYVWSS 284
           INF IY+WSS
Sbjct: 856 INFNIYMWSS 885
>15623
          Length = 2811

 Score =  197 bits (502), Expect(2) = 2e-55,   Method: Compositional matrix adjust.
 Identities = 101/184 (54%), Positives = 133/184 (72%)
 Frame = -1

Query: 96  NKEIFLRELISNASDALDKIRLISLTDENALAGNEELTVKIKCDKEKNLLHVTDTGVGMT 155
            +EIFLRELISN+SDALDKIR  SLTD + L   ++L ++I  DKE+  L + D+G+GMT
Sbjct: 588 QQEIFLRELISNSSDALDKIRYESLTDPSKLDAGKDLHIRIVPDKERKTLTIEDSGIGMT 409

Query: 156 REELVKNLGTIAKSGTSEFLNKMTEAQEDGQSTSELIGQFGVGFYSAFLVADKVIVTSKH 215
           + +LV NLGTIAKSGT  F+    EA + G   S +IGQFGVGFYSA+LVAD+V+V SK+
Sbjct: 408 KADLVNNLGTIAKSGTKAFM----EALQAGADIS-MIGQFGVGFYSAYLVADRVVVESKN 244

Query: 216 NNDTQHIWESDSNEFSVIADPRGNTLGRGTTITLVLKEEASDYLELDTIKNLVRKYSQFI 275
           N+D Q+ WES +     IA P G  +GRGT ITL +KE+  +YLE   IK +++K+SQFI
Sbjct: 243 NDDEQYTWESSAGGSFTIAAPTGTPMGRGTRITLFMKEDQQEYLEERRIKEVIKKHSQFI 64

Query: 276 NFPI 279
            +PI
Sbjct: 63  GYPI 52

 Score = 37.4 bits (85), Expect(2) = 2e-55,   Method: Compositional matrix adjust.
 Identities = 15/25 (60%), Positives = 20/25 (80%)
 Frame = -2

Query: 74  EKFAFQAEVNRMMKLIINSLYKNKE 98
           E FAFQAE+ ++M LIIN+ Y NK+
Sbjct: 653 ETFAFQAEIAQLMSLIINTFYSNKK 579
>27487
          Length = 377

 Score =  104 bits (260), Expect = 1e-22,   Method: Compositional matrix adjust.
 Identities = 53/127 (41%), Positives = 78/127 (61%), Gaps = 3/127 (2%)
 Frame = -3

Query: 450 TLQQHXXXXXXXXXXXXXXXDMIKKIADEKYND---TFWKEFGTNIKLGVIEDHSNRTRL 506
           TLQQ+               +M  +IA+   ND    F+++F  N+KLG+ ED +NRT+L
Sbjct: 375 TLQQNKILKVIKKNIVKKCLEMFAEIAEN--NDDYKKFYEQFSKNLKLGIHEDTTNRTKL 202

Query: 507 AKLLRFQSSHHSTDITSLDQYVERMKEKQDKIYFMAGSSRKEAESSPFVERLLKKGYEVI 566
             L+RF +S    D  SL +Y+ RMKE Q  I+++ G SR   ++SPF+E+L KKGYEV+
Sbjct: 201 VDLMRFHTSKSGEDQISLKEYIARMKEGQKDIFYITGESRAAVQASPFIEQLRKKGYEVL 22

Query: 567 YLTEPVD 573
           YL +P+D
Sbjct: 21  YLVDPID 1
>25874
          Length = 476

 Score = 69.7 bits (169), Expect = 4e-12,   Method: Compositional matrix adjust.
 Identities = 37/93 (39%), Positives = 57/93 (61%), Gaps = 2/93 (2%)
 Frame = +1

Query: 191 LIGQFGVGFYSAFLVADKV-IVTSKHNNDTQHI-WESDSNEFSVIADPRGNTLGRGTTIT 248
           LIGQFGVGFYS F+V D+V + T  H   +  + W SD +    +++  G  + RGT I 
Sbjct: 1   LIGQFGVGFYSTFMVGDRVDVFTKSHQPGSPALKWSSDGSGAYEVSEAEG--VQRGTKIV 174

Query: 249 LVLKEEASDYLELDTIKNLVRKYSQFINFPIYV 281
           + LK ++ D+ + + I  +V+KYS F+  PIY+
Sbjct: 175 VHLKGDSYDFAKEEIITGVVKKYSNFVGVPIYL 273
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|71067352|ref|NP_032161.2| solute carrier family 6
member 9 [Mus musculus]
         (633 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

08387                                                                 267   e-106
15924                                                                 358   4e-99
08953                                                                 330   1e-90
18526                                                                 229   4e-60
32211                                                                 129   2e-54
14556                                                                 183   2e-46
19604                                                                 159   2e-39
33291                                                                  86   5e-25
02570                                                                 100   2e-21
21405                                                                  85   3e-20
21870                                                                  84   6e-20
25926                                                                  76   5e-14
14638                                                                  69   4e-12
26038                                                                  66   4e-11
26872                                                                  54   1e-07
31151                                                                  53   3e-07
28188                                                                  29   4.5  
>08387
          Length = 4991

 Score =  267 bits (683), Expect(3) = e-106,   Method: Compositional matrix adjust.
 Identities = 159/432 (36%), Positives = 241/432 (55%), Gaps = 13/432 (3%)
 Frame = -2

Query: 200  VLKLSDDIGNFGEVRLPLLGCLGVSWVVVFLCLIRGVKSSGKVVYFTATFPYVVLTILFV 259
            VLK+SD I + G V+  L  CL ++WVVV+ C+ +G++SSGKV+Y TAT PY+ + IL +
Sbjct: 4417 VLKISDGIDDMGTVKWDLALCLLLAWVVVYACICKGIRSSGKVMYVTATSPYIFMLILLI 4238

Query: 260  RGVTLEGAFTGIMYYLTPQWDKILEAKVWGDAASQIFYSLGCAWGGLITMASYNKFHNNC 319
            R   L+GA  G+ +YLTP   K+ E +VW DA +QIF+S   A G L  + SYNKF +N 
Sbjct: 4237 RNSLLDGAKEGVDFYLTPNMTKLGEMEVWVDAGTQIFFSSSIALGTLTALGSYNKFKHNS 4058

Query: 320  YRDSVIISITNCATSVYAGFVIFSILGFMANHLGVDVSRVADHGPGLAFVAYPEALTLLP 379
            YRDSVI ++ N  TS +AGF++F+ILG+MA      +  VA+ GPGLAF+AYP+A+  +P
Sbjct: 4057 YRDSVIFALVNSVTSFFAGFIVFTILGYMAKLQNRPIKDVAESGPGLAFIAYPKAVAQMP 3878

Query: 380  ISPXXXXXXXXXXXXXXXGTQFCLLETLVTAIVDEVGNEWILQK--KTYVTLG-VAVAGF 436
            +SP                +QF  +E +VT IVD+     +L+K  +  + +G + +  F
Sbjct: 3877 LSPLWSILFFLMVILLGLDSQFVGVEGVVTTIVDQYPR--LLRKGYRKEIFIGFICIIMF 3704

Query: 437  LLGIPLTSQAGIYWLLLMDNYAASFSLVVISCIMCVSIMYIYGHRNYFQDIQMMLG---- 492
             +G+ + S  G+Y   L D Y+ S  +++++    + I YIYG   +  +I+MMLG    
Sbjct: 3703 FVGLAMVSNGGMYVFQLFDYYSGSRIILLVAFFELIGISYIYGVFRFLDNIKMMLGDHWM 3524

Query: 493  FPPPLFFQICWRFVSPAIIFFILIFTVIQY------RPITYNHYQYPGWAVAIGFLMALS 546
                 F  +CW  +SPA    I + + I Y      RP +   Y YP WAV IG+ +A S
Sbjct: 3523 VKTLPFMVVCWTVLSPAFCIAIFVMSAINYSELDYARPGSKGTYVYPDWAVGIGWALAAS 3344

Query: 547  SVICIPLYALFQLCRTDGDTLLQRLKNATKPSRDWGPALLEHRTGRYAPTTTPSPEDGFE 606
            S + IP+ A+++  + +G T L+ LK   KP       L E   G            G +
Sbjct: 3343 SAVWIPIVAIYKWVK-NGAT-LEALKLLCKPYGLKEHQLREQDKGERTLADLERERAGEQ 3170

Query: 607  VQPLHPDKAQIP 618
                + ++A +P
Sbjct: 3169 SYNGNVNQAYVP 3134

 Score = 98.6 bits (244), Expect(3) = e-106,   Method: Compositional matrix adjust.
 Identities = 44/108 (40%), Positives = 66/108 (61%)
 Frame = -1

Query: 64   AFMFPYFIMLIFCGIPLFFMELSFGQFASQGCLGVWRISPMFKGVGYGMMVVSTYIGIYY 123
            AF+ PYFI +IF GIPLF++E++ GQF ++G L  W + P+ +G+G    ++  ++  YY
Sbjct: 4790 AFLIPYFICVIFGGIPLFYLEVAVGQFMNRGGLQAWNLVPILQGIGLASCIIVFFLNCYY 4611

Query: 124  NVVICIAFYYFFSSMTHVLPWAYCNNPWNTPDCAGVLDASNLTNGSRP 171
            NV++  AFYYFFSS T  LPW  C++ WN      V   + +     P
Sbjct: 4610 NVILTWAFYYFFSSFTSELPWETCDHDWNNKTVCAVDFQAKVNETGDP 4467

 Score = 60.1 bits (144), Expect(3) = e-106,   Method: Compositional matrix adjust.
 Identities = 26/56 (46%), Positives = 34/56 (60%)
 Frame = -3

Query: 8    GMLNGAVPSEATKKDQNLTRGNWGNQIEFVLTSVGYAVGLGNVWRFPYLCYRNGGG 63
            G  +G    E  +      R  WG   +F+L  +G++VGLGNVWRFPYLCY+NG G
Sbjct: 4956 GRADGVKEGEDEEGKDLNKREQWGRAFDFLLACIGFSVGLGNVWRFPYLCYKNGEG 4789
>15924
          Length = 2588

 Score =  358 bits (919), Expect = 4e-99,   Method: Compositional matrix adjust.
 Identities = 182/412 (44%), Positives = 264/412 (64%), Gaps = 2/412 (0%)
 Frame = +3

Query: 190 SPSEEYWRLYVLKLSD--DIGNFGEVRLPLLGCLGVSWVVVFLCLIRGVKSSGKVVYFTA 247
           SP+ +Y   YVL+L++  D+ N G + L ++  L ++W+++F CL++GVKSSGKVVYFTA
Sbjct: 69  SPAADYLSQYVLRLNEATDMANLGGISLKMILTLALAWLLIFFCLMKGVKSSGKVVYFTA 248

Query: 248 TFPYVVLTILFVRGVTLEGAFTGIMYYLTPQWDKILEAKVWGDAASQIFYSLGCAWGGLI 307
           TFPYV+L +L VRGVTLEG   G+ +Y+ P+WDK+ +AKVWGDAA+QIFYSLG  +GGL+
Sbjct: 249 TFPYVILVVLLVRGVTLEGHLDGVKFYVIPEWDKLADAKVWGDAATQIFYSLGVGFGGLL 428

Query: 308 TMASYNKFHNNCYRDSVIISITNCATSVYAGFVIFSILGFMANHLGVDVSRVADHGPGLA 367
           TMASYNKF NNCYRD++++++ NC+TS++AGF IFS+LG MA+     V  VA  GPGLA
Sbjct: 429 TMASYNKFKNNCYRDAIMVAVINCSTSIFAGFAIFSLLGHMAHVNNQAVEDVASSGPGLA 608

Query: 368 FVAYPEALTLLPISPXXXXXXXXXXXXXXXGTQFCLLETLVTAIVDEVGNEWILQKKTYV 427
           FVAYPE +T LP                   +QF ++ET+++ I D      + ++K   
Sbjct: 609 FVAYPEGITKLPAQSLWSFLFFFMILTLGLDSQFAMMETVISGISDMFPRT-LRKRKVLF 785

Query: 428 TLGVAVAGFLLGIPLTSQAGIYWLLLMDNYAASFSLVVISCIMCVSIMYIYGHRNYFQDI 487
           T    + GFLLGIP  ++ G++ L LMD Y+ S++L+ ++    + IMY+YG RN+  D+
Sbjct: 786 TFCACLVGFLLGIPQATKGGMWVLTLMDWYSGSYNLMFVALAELICIMYVYGWRNFSNDV 965

Query: 488 QMMLGFPPPLFFQICWRFVSPAIIFFILIFTVIQYRPITYNHYQYPGWAVAIGFLMALSS 547
           +MM+GF P +++   W  ++P  I FI+I   IQY P +Y+ Y++  W   +G++M    
Sbjct: 966 EMMVGFKPNIYWLANWLVITPIAIGFIIIIGAIQYTPASYDGYEFEDWVQGLGWVMVTVP 1145

Query: 548 VICIPLYALFQLCRTDGDTLLQRLKNATKPSRDWGPALLEHRTGRYAPTTTP 599
           +  I +    Q+ R         +    K   DWGPA  E RTGRYAP   P
Sbjct: 1146IASIFVVGFVQMARYG-------VPGCFKAQPDWGPANPEDRTGRYAPVGLP 1280
>08953
          Length = 2245

 Score =  330 bits (846), Expect = 1e-90,   Method: Compositional matrix adjust.
 Identities = 167/376 (44%), Positives = 247/376 (65%)
 Frame = +1

Query: 221 LGVSWVVVFLCLIRGVKSSGKVVYFTATFPYVVLTILFVRGVTLEGAFTGIMYYLTPQWD 280
           L ++W+++F CL++GVKSSGKVVYFTATFPYV+L +L VRGVTL G   GI +Y  P+WD
Sbjct: 16  LALAWILIFFCLMKGVKSSGKVVYFTATFPYVILLVLLVRGVTLSGHLEGIKFYTIPKWD 195

Query: 281 KILEAKVWGDAASQIFYSLGCAWGGLITMASYNKFHNNCYRDSVIISITNCATSVYAGFV 340
           K+ +AKVWGDAA+QIFYSLG  +GGL+TM+SY+KF NNC+RD++++++ NC TS++AGF 
Sbjct: 196 KLADAKVWGDAATQIFYSLGVGFGGLLTMSSYSKFKNNCHRDAIMVALINCGTSIFAGFA 375

Query: 341 IFSILGFMANHLGVDVSRVADHGPGLAFVAYPEALTLLPISPXXXXXXXXXXXXXXXGTQ 400
           IF++LG MA     DV +VAD GPGLAFVAYPE +T LP                   +Q
Sbjct: 376 IFALLGHMAYVTNQDVDKVADSGPGLAFVAYPEGITKLPAMSLWAFLFFFMILTLGLDSQ 555

Query: 401 FCLLETLVTAIVDEVGNEWILQKKTYVTLGVAVAGFLLGIPLTSQAGIYWLLLMDNYAAS 460
           F ++ET+++ I D      + + KT+ T    + GFLLGIP  ++ G++ L LMD Y+ S
Sbjct: 556 FAMMETVISGISDMF-PRLLRKHKTFFTFICCLVGFLLGIPQATKGGMWVLTLMDWYSGS 732

Query: 461 FSLVVISCIMCVSIMYIYGHRNYFQDIQMMLGFPPPLFFQICWRFVSPAIIFFILIFTVI 520
           ++L+ ++    + +MY+YG   +++DI+MM+G  P  +++I W  ++P  I FI++   +
Sbjct: 733 YNLMFVALAEIICLMYVYGFNKFYEDIEMMIGHKPNYYWRIHWLAITPIAIIFIIVIGAV 912

Query: 521 QYRPITYNHYQYPGWAVAIGFLMALSSVICIPLYALFQLCRTDGDTLLQRLKNATKPSRD 580
           QY P +Y+ Y++  W   +G++M    +  I +    Q+ R         +    KP+ D
Sbjct: 913 QYTPASYSGYEFEBWVQGLGWVMVSVPIALIFIVGFVQMFRYG-------VPGCFKPTPD 1071

Query: 581 WGPALLEHRTGRYAPT 596
           WGPA  E+RTGRYAPT
Sbjct: 1072WGPADPENRTGRYAPT 1119
>18526
          Length = 537

 Score =  229 bits (583), Expect = 4e-60,   Method: Compositional matrix adjust.
 Identities = 109/174 (62%), Positives = 137/174 (78%)
 Frame = -2

Query: 209 NFGEVRLPLLGCLGVSWVVVFLCLIRGVKSSGKVVYFTATFPYVVLTILFVRGVTLEGAF 268
           + G VR  LL  L VSW+ VFLCL +GVK  GKV++F A FPY+VL +L +RGVTL GA 
Sbjct: 536 SLGTVRWQLLITLAVSWLCVFLCLFKGVKVLGKVMHFAAPFPYMVLLVLLIRGVTLPGAI 357

Query: 269 TGIMYYLTPQWDKILEAKVWGDAASQIFYSLGCAWGGLITMASYNKFHNNCYRDSVIISI 328
            GI +Y+ P+W+K+LE +VWGDAA QIFYS+G AWGG+ITMASYNKF+NN YRD++I+ +
Sbjct: 356 DGISFYIIPRWEKLLEFQVWGDAALQIFYSVGMAWGGIITMASYNKFNNNVYRDAMIVPL 177

Query: 329 TNCATSVYAGFVIFSILGFMANHLGVDVSRVADHGPGLAFVAYPEALTLLPISP 382
            NC TS++AGFVIFSILGFMA+  G +V  +   GPGL FVAYPEA++ LPISP
Sbjct: 176 INCGTSIFAGFVIFSILGFMAHEAGKNVEDIVTQGPGLTFVAYPEAVSKLPISP 15
>32211
          Length = 836

 Score =  129 bits (325), Expect(2) = 2e-54,   Method: Compositional matrix adjust.
 Identities = 60/112 (53%), Positives = 83/112 (74%)
 Frame = -2

Query: 231 CLIRGVKSSGKVVYFTATFPYVVLTILFVRGVTLEGAFTGIMYYLTPQWDKILEAKVWGD 290
           C+ +G+KSSGKV+YFTAT PYV++ +L +RGVTLEGA TG+ YYL P+W ++ + +VW D
Sbjct: 835 CIWKGIKSSGKVMYFTATTPYVLMFVLLIRGVTLEGASTGLKYYLLPEWSRLKDPQVWVD 656

Query: 291 AASQIFYSLGCAWGGLITMASYNKFHNNCYRDSVIISITNCATSVYAGFVIF 342
           A +QIF+S   + G L  + SYN+F +N +RDSV  ++ N  TS  AGFVIF
Sbjct: 655 AGTQIFFSYSISLGTLTALGSYNRFTHNVFRDSVCFAVINTFTSFLAGFVIF 500

 Score =  101 bits (252), Expect(2) = 2e-54,   Method: Compositional matrix adjust.
 Identities = 54/162 (33%), Positives = 90/162 (55%), Gaps = 1/162 (0%)
 Frame = -1

Query: 343 SILGFMANHLGVDVSRVADHGPGLAFVAYPEALTLLPISPXXXXXXXXXXXXXXXGTQFC 402
           SILGFMA   G+DV+ VA+ GPGLAF+AYPEA+  LPI+P                +QF 
Sbjct: 500 SILGFMAVRQGLDVADVAESGPGLAFIAYPEAVAQLPIAPLWSVMFFVMVILLGLDSQFV 321

Query: 403 LLETLVTAIVDEVGNEWILQKKTYVTLG-VAVAGFLLGIPLTSQAGIYWLLLMDNYAASF 461
            +E  +TA+VD          +  V +  + V  + +G+ + ++ G+Y   L D Y+AS 
Sbjct: 320 GVEGFITAVVDLYPRVLRRGHRREVFIAIICVIAYFIGLSMVTEGGMYVFQLFDYYSASR 141

Query: 462 SLVVISCIMCVSIMYIYGHRNYFQDIQMMLGFPPPLFFQICW 503
            ++V++   C+++ Y+YG   ++ +++MM GF      ++ W
Sbjct: 140 IVLVVAFFECITVAYVYGVDRFYDNLEMMFGFRMGPLMKVSW 15
>14556
          Length = 552

 Score =  183 bits (464), Expect = 2e-46,   Method: Compositional matrix adjust.
 Identities = 82/144 (56%), Positives = 108/144 (75%), Gaps = 3/144 (2%)
 Frame = -2

Query: 16  SEATKKDQNLTRGNWGNQIEFVLTSVGYAVGLGNVWRFPYLCYRNGGGAFMFPYFIMLIF 75
           SE+    +++ RGNWG+Q++F+L+ VGYAVGLGNVWRFPYL YRNGG  F+FPY IMLI 
Sbjct: 452 SESKMGSEDIERGNWGSQLDFLLSCVGYAVGLGNVWRFPYLAYRNGGATFLFPYIIMLII 273

Query: 76  CGIPLFFMELSFGQFASQGCLGVWRISPMFKGVGYGMMVVSTYIGIYYNVVICIAFYYFF 135
            G+PLFF+EL+ GQFAS+G + VW++SP F G+G+ M ++S  + IYYNV+I  A YY F
Sbjct: 272 AGLPLFFLELALGQFASEGPITVWKMSPFFSGIGFAMCIISGVVSIYYNVIITYAIYYMF 93

Query: 136 SSMTHV---LPWAYCNNPWNTPDC 156
            S  ++   LPWA CN+ W TP C
Sbjct: 92  VSFVNLDNDLPWASCNHTWATPSC 21
>19604
          Length = 419

 Score =  159 bits (403), Expect = 2e-39,   Method: Compositional matrix adjust.
 Identities = 76/133 (57%), Positives = 100/133 (75%)
 Frame = -3

Query: 211 GEVRLPLLGCLGVSWVVVFLCLIRGVKSSGKVVYFTATFPYVVLTILFVRGVTLEGAFTG 270
           G  R  L  CL +SWVVV LCLI+G+KSSGKVVYFTATFPYV+L IL +RG  LEGA  G
Sbjct: 399 GTPRWRLALCLLLSWVVVILCLIKGIKSSGKVVYFTATFPYVILIILLIRGALLEGAKEG 220

Query: 271 IMYYLTPQWDKILEAKVWGDAASQIFYSLGCAWGGLITMASYNKFHNNCYRDSVIISITN 330
           + +++ P+WDK+ + KVW  AA Q+F+SL  ++GG+I   SYNKF NN Y D+++IS+ +
Sbjct: 219 VEFFIIPEWDKLTDVKVWVAAAGQMFFSLSVSFGGIIMFGSYNKFTNNVYGDALLISVMD 40

Query: 331 CATSVYAGFVIFS 343
             TSV AGFV+F+
Sbjct: 39  LVTSVIAGFVVFT 1
>33291
          Length = 467

 Score = 85.5 bits (210), Expect(3) = 5e-25,   Method: Composition-based stats.
 Identities = 40/67 (59%), Positives = 46/67 (68%)
 Frame = -1

Query: 313 NKFHNNCYRDSVIISITNCATSVYAGFVIFSILGFMANHLGVDVSRVADHGPGLAFVAYP 372
           ++  NN  RDS+I+ I NC TS YAGF IFSILGFMA   GV+V  V   G GL FVAYP
Sbjct: 341 HQVQNNAIRDSIIVPIINCLTSFYAGFAIFSILGFMAASKGVEVEDVTTDGTGLVFVAYP 162

Query: 373 EALTLLP 379
           EAL  +P
Sbjct: 161 EALARMP 141

 Score = 46.2 bits (108), Expect(3) = 5e-25,   Method: Composition-based stats.
 Identities = 22/45 (48%), Positives = 29/45 (64%)
 Frame = -2

Query: 271 IMYYLTPQWDKILEAKVWGDAASQIFYSLGCAWGGLITMASYNKF 315
           I +YL P   K+ E+ VW  AA+QIF+SL  + G L  M+SY KF
Sbjct: 466 IKFYLQPDASKLSESSVWLAAAAQIFFSLSTSTGSLTAMSSYTKF 332

 Score = 21.6 bits (44), Expect(3) = 5e-25,   Method: Composition-based stats.
 Identities = 10/17 (58%), Positives = 12/17 (70%)
 Frame = -3

Query: 398 GTQFCLLETLVTAIVDE 414
           GTQ    ETL+TA+ DE
Sbjct: 87  GTQIPSAETLLTALQDE 37
>02570
          Length = 1067

 Score =  100 bits (249), Expect = 2e-21,   Method: Compositional matrix adjust.
 Identities = 65/227 (28%), Positives = 118/227 (51%), Gaps = 10/227 (4%)
 Frame = -3

Query: 368  FVAYPEALTLLPISPXXXXXXXXXXXXXXXGTQFCLLETLVTAIVDEVGNEWILQKKTYV 427
            FVAYPEAL+ LP                   ++F L+ET++T I DE+      + K+ +
Sbjct: 1065 FVAYPEALSNLPPPQLWSVLFFFMLFTLGLDSEFGLMETILTCIQDEMPR--XRKYKSVM 892

Query: 428  TLGVAVAGFLLGIPLTSQAGIYWLLLMDNYAASFSLVVISCIMCVSIMYIYGHRNYFQDI 487
             +G  +  + L +P     G Y + LMD+Y A FS++++SC   +S+M+ YG   + +D+
Sbjct: 891  CIGFGIGCYFLALPCVCNGGDYVVTLMDHYGADFSVLILSCFEVMSVMWXYGVMRFQKDL 712

Query: 488  QMMLGFPP---PLFFQICWRFVSPAIIFFILIFTVIQYRPITYNH---YQYPGWAVAIGF 541
            + MLG  P   P ++  CW  ++P +I  + ++ +++Y P  Y+    + YP +A  IG+
Sbjct: 711  EYMLGRRPMGWP-YWVFCWS-IAPILIAALFLYRMVEYVPPHYDSEKLHPYPQFAQNIGW 538

Query: 542  LMALSSVICIPLYALFQLCRTDGDTLLQRLKNAT----KPSRDWGPA 584
             + +  +  IPL+ ++   RT      Q +        +P+++W PA
Sbjct: 537  FLLVVVLCPIPLWFIYHAVRTYRQNSDQPISEIIAIMFRPTKEWRPA 397
>21405
          Length = 542

 Score = 85.1 bits (209), Expect(2) = 3e-20,   Method: Compositional matrix adjust.
 Identities = 43/131 (32%), Positives = 76/131 (58%), Gaps = 1/131 (0%)
 Frame = +2

Query: 416 GNEWILQKKTYVTLGVAVAGFLLGIPLTSQAGIYWLLLMDNYAAS-FSLVVISCIMCVSI 474
           G+ + +++K      V +  +L+G+   +Q G+Y   ++D+YA S F L+ +    CVSI
Sbjct: 149 GHNYSVKRKEIFIAIVCMLSYLVGLTCITQGGMYIFQILDSYAVSGFCLLWLIFFECVSI 328

Query: 475 MYIYGHRNYFQDIQMMLGFPPPLFFQICWRFVSPAIIFFILIFTVIQYRPITYNHYQYPG 534
            + YG   ++  I+ M+G+ P ++++ CW F +PAI   +  F ++Q++ I Y  Y YP 
Sbjct: 329 SWCYGVDRFYDGIKDMIGYYPTVWWKFCWCFTTPAICLGVFFFNIVQWKSIKYLDYSYPW 508

Query: 535 WAVAIGFLMAL 545
           WA A G+  AL
Sbjct: 509 WAHAFGWFTAL 541

 Score = 32.0 bits (71), Expect(2) = 3e-20,   Method: Compositional matrix adjust.
 Identities = 15/46 (32%), Positives = 22/46 (47%)
 Frame = +1

Query: 369 VAYPEALTLLPISPXXXXXXXXXXXXXXXGTQFCLLETLVTAIVDE 414
           + YP A+  LP SP                +QFC +E  +TA++DE
Sbjct: 10  LVYPSAVLQLPGSPMWSCLFFFMLLLIGLDSQFCTMEGFITAVIDE 147
>21870
          Length = 347

 Score = 83.6 bits (205), Expect(2) = 6e-20,   Method: Compositional matrix adjust.
 Identities = 35/54 (64%), Positives = 44/54 (81%)
 Frame = -2

Query: 22  DQNLTRGNWGNQIEFVLTSVGYAVGLGNVWRFPYLCYRNGGGAFMFPYFIMLIF 75
           +++ TR  WG  +EF++T +G+AVGLGNVWRFPYLCYRNGGGAF+ PY I L F
Sbjct: 214 EESGTRATWGRHLEFIVTCIGFAVGLGNVWRFPYLCYRNGGGAFLIPYLISLGF 53

 Score = 32.3 bits (72), Expect(2) = 6e-20,   Method: Compositional matrix adjust.
 Identities = 14/20 (70%), Positives = 18/20 (90%)
 Frame = -3

Query: 73 LIFCGIPLFFMELSFGQFAS 92
          L+F GIPLF +E++FGQFAS
Sbjct: 60 LVFIGIPLFCLEITFGQFAS 1
>25926
          Length = 675

 Score = 75.9 bits (185), Expect = 5e-14,   Method: Compositional matrix adjust.
 Identities = 36/106 (33%), Positives = 61/106 (57%), Gaps = 4/106 (3%)
 Frame = +1

Query: 476 YIYGHRNYFQDIQMMLGFPPPLFFQICWRFVSPAIIFFILIFTVIQYRPITYNH----YQ 531
           ++YG   ++ +++MM GF    + +ICW  ++P     I I   I Y  +TY      Y+
Sbjct: 1   FVYGVNRFYDNLEMMFGFRVGPWMKICWTVLTPLYTMVIFIMGCISYSDLTYKRKTVTYE 180

Query: 532 YPGWAVAIGFLMALSSVICIPLYALFQLCRTDGDTLLQRLKNATKP 577
           YP WA+ +G+ M   S+I IPL  +F++   DG + ++R+K+ TKP
Sbjct: 181 YPSWAIGVGWSMVAMSIIFIPLVMVFRMLTADG-SFVERVKHLTKP 315
>14638
          Length = 421

 Score = 69.3 bits (168), Expect = 4e-12,   Method: Compositional matrix adjust.
 Identities = 43/126 (34%), Positives = 71/126 (56%), Gaps = 6/126 (4%)
 Frame = -3

Query: 435 GFLLGIPLTSQAGIYWLLLMDNYAASFSLVVISCIMCVSIMYIYGHRNYFQDIQMMLGFP 494
           GF+LG+P T+Q G Y L L+D +   F L+++     V+I+++YG R   +D+ MM+G  
Sbjct: 371 GFILGLPQTTQGGTYILDLLDIFVG-FPLLLVGFFEFVAIVWVYGFRRISEDVMMMMGDH 195

Query: 495 P------PLFFQICWRFVSPAIIFFILIFTVIQYRPITYNHYQYPGWAVAIGFLMALSSV 548
           P        +F   W  VSP ++  I++F  + Y PIT     YP WA  +G+L+    +
Sbjct: 194 PITRMVYDFYFSWTWLVVSPGLLLAIIVFDSVNYVPITGP--GYPPWAETLGWLVVTFIM 21

Query: 549 ICIPLY 554
           + IP++
Sbjct: 20  MWIPVW 3
>26038
          Length = 426

 Score = 66.2 bits (160), Expect = 4e-11,   Method: Compositional matrix adjust.
 Identities = 32/118 (27%), Positives = 68/118 (57%), Gaps = 1/118 (0%)
 Frame = -2

Query: 404 LETLVTAIVDEVGNEWILQ-KKTYVTLGVAVAGFLLGIPLTSQAGIYWLLLMDNYAASFS 462
           LE+ +T + DE+     ++  +  +TL V  + F   +P  ++ GIY   ++D +AA  S
Sbjct: 356 LESPLTGLHDELKTVMRMRYSREVLTLVVVGSAFFCSLPCLTEGGIYVFTILDTFAAGTS 177

Query: 463 LVVISCIMCVSIMYIYGHRNYFQDIQMMLGFPPPLFFQICWRFVSPAIIFFILIFTVI 520
           ++       +++ + YG   + +D++ M G  P +++++CW+FV P ++F I+I ++I
Sbjct: 176 ILFTVLCQVIAVSWFYGINQFCRDVEKMTGSQPSMYWRVCWKFVCPILLFIIVISSII 3
>26872
          Length = 406

 Score = 54.3 bits (129), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 34/130 (26%), Positives = 65/130 (50%)
 Frame = +2

Query: 366 LAFVAYPEALTLLPISPXXXXXXXXXXXXXXXGTQFCLLETLVTAIVDEVGNEWILQKKT 425
           L FVAYPEA++ LP +                 + F   E ++TA+ DE     + + + 
Sbjct: 2   LVFVAYPEAISTLPGASFWAVIFFLMLLTLGLDSSFGGSEAIITALSDEF--PVLRRHRE 175

Query: 426 YVTLGVAVAGFLLGIPLTSQAGIYWLLLMDNYAASFSLVVISCIMCVSIMYIYGHRNYFQ 485
              L + V  F++G+   ++ G+Y + L+D +AA +S++       +++ + YG   + +
Sbjct: 176 LFVLALFVLYFIVGLASCAEGGLYVVNLLDQFAAGYSILFAVFFETLAVSWAYGLDRFSE 355

Query: 486 DIQMMLGFPP 495
           D++ MLG  P
Sbjct: 356 DLEAMLGHRP 385
>31151
          Length = 322

 Score = 53.1 bits (126), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 28/77 (36%), Positives = 47/77 (61%)
 Frame = -2

Query: 476 YIYGHRNYFQDIQMMLGFPPPLFFQICWRFVSPAIIFFILIFTVIQYRPITYNHYQYPGW 535
           +IYG     +DI +MLG  PP    + W+F++PA++  +L+FT++ Y P +Y  Y Y   
Sbjct: 318 WIYGVARIREDICLMLGHGPPFILTVFWKFITPALLLVVLVFTLMNYTPPSYGQYVYGTG 139

Query: 536 AVAIGFLMALSSVICIP 552
               G+++ALSS++  P
Sbjct: 138 GHVFGWVVALSSLLPSP 88
>28188
          Length = 1255

 Score = 29.3 bits (64), Expect = 4.5,   Method: Compositional matrix adjust.
 Identities = 14/48 (29%), Positives = 23/48 (47%)
 Frame = +1

Query: 319 CYRDSVIISITNCATSVYAGFVIFSILGFMANHLGVDVSRVADHGPGL 366
           C   +V   +T  + S++          F+  H+G D SR+ DH PG+
Sbjct: 598 CLHXAVTHLLTTLSWSIWTFLSPRIWASFVQLHMGWDCSRMVDHNPGI 741
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|111154063|ref|NP_892035.2| structure specific
recognition protein 1 isoform 1 [Mus musculus]
         (708 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

00782                                                                 378   e-105
19432                                                                 205   4e-53
26689                                                                 147   2e-35
11933                                                                  57   2e-08
33187                                                                  57   3e-08
24607                                                                  47   2e-05
14405                                                                  42   7e-04
21088                                                                  37   0.030
30503                                                                  35   0.12 
27304                                                                  32   0.61 
00223                                                                  30   4.7  
29687                                                                  29   6.2  
>00782
          Length = 1035

 Score =  378 bits (970), Expect = e-105,   Method: Compositional matrix adjust.
 Identities = 171/273 (62%), Positives = 224/273 (82%), Gaps = 3/273 (1%)
 Frame = +3

Query: 195 TGDAICIFRELQCLTPRGRYDIRIYPTFLHLHGKTFDYKIPYTTVLRLFLLPHKDQRQMF 254
           TGDA+    E+QCLTPRGRYDI++YPTFL LHGKTFDYKIPYTT+LRLFLLPHKD RQMF
Sbjct: 3   TGDAVVTLSEMQCLTPRGRYDIKMYPTFLQLHGKTFDYKIPYTTILRLFLLPHKDGRQMF 182

Query: 255 FVISLDPPIKQGQTRYHFLILLFSKDEDISLTLNMNEEEVEKRFEGRLTKNMSGSLYEMV 314
           FV+SLDPPIKQGQTRYHFLILLF+K++++++ + MNEE++++++E +L   MSG  YE+V
Sbjct: 183 FVVSLDPPIKQGQTRYHFLILLFNKEDEMTVEMGMNEEDLKQKYEDQLQSEMSGFEYEIV 362

Query: 315 SRVMKALVNRKITVPGNFQGHSGAQCITCSYKASSGLLYPLERGFIYVHKPPVHIRFDEI 374
           SR+ K +  RKITVPGNF GHSG Q ++CSYKA++G LYPLERGFI+VHKPP+HIRFDEI
Sbjct: 363 SRIFKVITQRKITVPGNFIGHSGTQAVSCSYKAATGFLYPLERGFIFVHKPPLHIRFDEI 542

Query: 375 SFVNFARGTTTTRSFDFEIETKQGTQYTFSSIEREEYGKLFDFVNAKKLNIKN-RGLKEG 433
             VNFAR   TTRSFDF++ETK G  Y F  IE+ E+ KL+++V++KKL +KN  G  + 
Sbjct: 543 VVVNFARNAGTTRSFDFDVETKTGNVYNFVGIEKNEFNKLYEYVSSKKLRVKNIGGPMDK 722

Query: 434 INPGYDDYADSDEDQ--HDAYLERMKEEGKIRE 464
            +  Y++ + SD+D+  HDAY+E+M++EG+ R+
Sbjct: 723 SSVTYEEMSGSDDDKGDHDAYMEKMRKEGQQRQ 821
>19432
          Length = 629

 Score =  205 bits (522), Expect = 4e-53,   Method: Compositional matrix adjust.
 Identities = 91/172 (52%), Positives = 128/172 (74%)
 Frame = +2

Query: 1   MAETLEFNDIFQEVKGSMNDGRLRLSRQGIIFKNSKTGKVDNIQAGELTEGIWRRVALGH 60
           M++  E++D+ QE++GS+N GRL+L R  +IFKN+KTGKVD  Q+ ++ +  W + A GH
Sbjct: 86  MSDFQEYSDVVQEIRGSLNPGRLKLQRNSVIFKNNKTGKVDQFQSSDIEKSQWLKRARGH 265

Query: 61  GLKLLTKNGHVYKYDGFRESEFEKLSDFFKTHYRLELMEKDLCVKGWNWGTVKFGGQLLS 120
            LK++ K G+ ++YDGF+E +FE+LS F +  Y + L + DL +KGWNWG  KF G  L+
Sbjct: 266 CLKMVLKTGNTHRYDGFKEPDFERLSKFLQEFYEMSLEKVDLSIKGWNWGLAKFEGNSLN 445

Query: 121 FDIGDQPVFEIPLSNVSQCTTGKNEVTLEFHQNDDAEVSLMEVRFYVPPTQE 172
           F++    VF+IPL+NVS  TT KNEVTLEFHQNDDA V+LMEVRF++PP Q+
Sbjct: 446 FELDQSLVFDIPLTNVSHSTTSKNEVTLEFHQNDDAAVNLMEVRFHIPPEQQ 601
>26689
          Length = 461

 Score =  147 bits (370), Expect = 2e-35,   Method: Compositional matrix adjust.
 Identities = 74/138 (53%), Positives = 96/138 (69%), Gaps = 2/138 (1%)
 Frame = +3

Query: 332 FQGHSGAQCITCSYKASSGLLYPLERGFIYVHKPPVHIRFDEISFVNFARGTTTTRSFDF 391
           F GHSG   + CS+KA++G LYPLERGFIY+HKPP+HIRF+EIS VNFAR   +TRSFDF
Sbjct: 21  FIGHSGTAAVGCSFKAAAGYLYPLERGFIYIHKPPLHIRFEEISSVNFARSGGSTRSFDF 200

Query: 392 EIETKQGTQYTFSSIEREEYGKLFDFVNAKKLNIKNRGLKEGINP--GYDDYADSDEDQH 449
           E+  K GT + FSSIE+EEY KLFD++  KKL++ N G  +G N   G   +      + 
Sbjct: 201 EVTLKNGTVHIFSSIEKEEYAKLFDYITQKKLHVSNIG--QG*NRL*GCRLWRFGQ*KRP 374

Query: 450 DAYLERMKEEGKIREENA 467
           DAYL R+K E + + E+ 
Sbjct: 375 DAYLARLKAEAREKXEDG 428
>11933
          Length = 1516

 Score = 57.0 bits (136), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 31/77 (40%), Positives = 49/77 (63%)
 Frame = +2

Query: 543 DPNAPKRPMSAYMLWLNASREKIKSDHPGISITDLSKKAGEIWKGMSKEKKEEWDRKAED 602
           DPN PKRPM+AY L+L   R  IK  + G+   ++ + AGE W+ MS E K+ +++++ +
Sbjct: 866 DPNKPKRPMTAYFLFLGDFR--IKMKNRGVDHKEILRLAGEEWRNMSAEDKKPYEKRSVE 1039

Query: 603 ARREYEKAMKEYEGGRG 619
           A ++YE  M+EY    G
Sbjct: 1040AGKKYEVEMEEYRKNEG 1090

 Score = 35.4 bits (80), Expect = 0.086,   Method: Compositional matrix adjust.
 Identities = 25/79 (31%), Positives = 37/79 (46%), Gaps = 1/79 (1%)
 Frame = +2

Query: 543 DPNAPKRPMSAYMLWLNASREKIKSDHPGIS-ITDLSKKAGEIWKGMSKEKKEEWDRKAE 601
           D N PKR  SAY  +L   RE        IS I + +K+    W+ M   +K+ ++  A 
Sbjct: 632 DANKPKRSTSAYXYFLAHCREVSAKQGKTISRIAEFTKECSAKWREMGGAQKKPFEESAA 811

Query: 602 DARREYEKAMKEYEGGRGD 620
             +  Y+K M  Y+G   D
Sbjct: 812 KDKARYDKEMALYKGKSTD 868
>33187
          Length = 644

 Score = 56.6 bits (135), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 27/73 (36%), Positives = 45/73 (61%)
 Frame = +3

Query: 543 DPNAPKRPMSAYMLWLNASREKIKSDHPGISITDLSKKAGEIWKGMSKEKKEEWDRKAED 602
           DPNAPKR +SA+  + N  R K+K+ +P   + D++K+ G  W  +  E K++++  AE 
Sbjct: 84  DPNAPKRSLSAFFWFCNDERNKVKALNPEFGVGDIAKELGRKWSDVDPEVKQKYESMAER 263

Query: 603 ARREYEKAMKEYE 615
            +  YE+ M EY+
Sbjct: 264 DKARYEREMTEYK 302
>24607
          Length = 1354

 Score = 47.4 bits (111), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 20/55 (36%), Positives = 36/55 (65%)
 Frame = -2

Query: 548 KRPMSAYMLWLNASREKIKSDHPGISITDLSKKAGEIWKGMSKEKKEEWDRKAED 602
           +R  +AYML+ N+ R K+ ++ PGI    +S+  G +W+ +SK++K  W RK++ 
Sbjct: 393 RRAPTAYMLYCNSQRPKVVAESPGIDFAQISRTLGVMWQCLSKKEKMMWRRKSKK 229
>14405
          Length = 600

 Score = 42.4 bits (98), Expect = 7e-04,   Method: Composition-based stats.
 Identities = 17/48 (35%), Positives = 31/48 (64%)
 Frame = -2

Query: 548 KRPMSAYMLWLNASREKIKSDHPGISITDLSKKAGEIWKGMSKEKKEE 595
           +R  +AYML+ N+ R K+ ++ PGI    +S+  G +W+ +SK+ K +
Sbjct: 254 RRAPTAYMLYCNSQRPKVVAESPGIDFAQISRTLGVMWQCLSKKGKND 111
>21088
          Length = 490

 Score = 37.0 bits (84), Expect = 0.030,   Method: Composition-based stats.
 Identities = 16/70 (22%), Positives = 38/70 (54%)
 Frame = -3

Query: 546 APKRPMSAYMLWLNASREKIKSDHPGISITDLSKKAGEIWKGMSKEKKEEWDRKAEDARR 605
           A KRPM+A+M++    R ++ +  P +    +SK  G++W+   +  ++ + + A+  + 
Sbjct: 332 AVKRPMNAFMVFAKMERRQMMAAQPELHNARISKHLGDVWRQCPQPLQDPYKQLAQCLKD 153

Query: 606 EYEKAMKEYE 615
            + +   EY+
Sbjct: 152 LHRQEHPEYK 123
>30503
          Length = 739

 Score = 34.7 bits (78), Expect = 0.12,   Method: Compositional matrix adjust.
 Identities = 16/65 (24%), Positives = 37/65 (56%)
 Frame = +1

Query: 551 MSAYMLWLNASREKIKSDHPGISITDLSKKAGEIWKGMSKEKKEEWDRKAEDARREYEKA 610
           ++ Y ++L +        HP +   ++ KK    +  +S EKK++W +KA +A  E+++ 
Sbjct: 16  LTPYNMFLKSKMPPYLQKHPELPRIEVQKKMKAKYMKLSAEKKKKWIQKAHNAVPEFDEE 195

Query: 611 MKEYE 615
           +++Y+
Sbjct: 196 VRQYQ 210
>27304
          Length = 512

 Score = 32.3 bits (72), Expect = 0.61,   Method: Composition-based stats.
 Identities = 14/42 (33%), Positives = 23/42 (54%)
 Frame = +3

Query: 548 KRPMSAYMLWLNASREKIKSDHPGISITDLSKKAGEIWKGMS 589
           KRPM+A+M +    R+ +    P +    +SK  G +WK +S
Sbjct: 387 KRPMNAFMAFAQFERKALMQVRPTLHNAVISKHLGSVWKRLS 512
>00223
          Length = 1944

 Score = 29.6 bits (65), Expect = 4.7,   Method: Compositional matrix adjust.
 Identities = 13/31 (41%), Positives = 19/31 (61%)
 Frame = +2

Query: 347 ASSGLLYPLERGFIYVHKPPVHIRFDEISFV 377
           A   + YPL R F+++     HIR +EISF+
Sbjct: 401 ARVHVFYPLTRVFLFLTNSSPHIRVEEISFI 493
>29687
          Length = 434

 Score = 29.3 bits (64), Expect = 6.2,   Method: Compositional matrix adjust.
 Identities = 15/38 (39%), Positives = 21/38 (55%)
 Frame = -2

Query: 559 NASREKIKSDHPGISITDLSKKAGEIWKGMSKEKKEEW 596
           NA RE   S   G  IT++S++ G  W+G    KK+ W
Sbjct: 271 NAKREDELSFCKGAIITNVSRQDGGWWRGDYGTKKQHW 158
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|13385624|ref|NP_080390.1| eukaryotic translation
initiation factor 2, subunit 1 alpha [Mus musculus]
         (315 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

07626                                                                 379   e-105
>07626
          Length = 1423

 Score =  379 bits (973), Expect = e-105,   Method: Compositional matrix adjust.
 Identities = 182/279 (65%), Positives = 223/279 (79%)
 Frame = +1

Query: 4   LSCRFYQHKFPEVEDVVMVNVRSIAEMGAYVSLLEYNNIEGMXXXXXXXXXXXXXXNKLI 63
           L+CRFY+++FPE++DVVMVNVRSIAEMGAYV LLEYNNIEGM              NKLI
Sbjct: 58  LTCRFYKNRFPEIDDVVMVNVRSIAEMGAYVHLLEYNNIEGMILLSELSRRRIRSINKLI 237

Query: 64  RIGRNECVVVIRVDKEKGYIDLSKRRVSPEEAIKCEDKFTKSKTVYSILRHVAEVLEYTK 123
           R+GRNECVVVIRVDK+KGYIDLSKRRVS EE +KCE+KF K+K V SILRHVAE+L Y+ 
Sbjct: 238 RVGRNECVVVIRVDKDKGYIDLSKRRVSAEEVLKCEEKFAKAKAVNSILRHVAELLGYSS 417

Query: 124 DEQLESLFQRTAWVFDDKYKRPGYGAYDAFKHAVSDPSILDSLDLNEDEREVLINNINRR 183
             +LE L+++TAW FD+KYK+PG  +Y+AFKHAVS+P +LD  ++++  +EVL+ NI R+
Sbjct: 418 SAKLEELYEKTAWYFDEKYKKPG-SSYEAFKHAVSNPEVLDECEIDDQTKEVLLENICRK 594

Query: 184 LTPQAVKIRADIEVACYGYEGIDAVKEALRAGLNCSTETMPIKINLIAPPRYVMTTTTLE 243
           L PQ+VKIRADIEVAC  YEG+DAVK AL+ GL  +TE MPIKINLIAPP YV+TT T+E
Sbjct: 595 LKPQSVKIRADIEVACTKYEGVDAVKRALKKGLEFTTEAMPIKINLIAPPLYVVTTQTME 774

Query: 244 RTEGLSVLNQAMAVIKEKIEEKRGVFNVQMEPKVVTDTD 282
           R+EGL VLN+A+  IKE I    GVFNVQ  P+VV+D D
Sbjct: 775 RSEGLEVLNKAVEAIKEDITGAGGVFNVQEAPRVVSDID 891
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|27369782|ref|NP_766146.1| gem (nuclear organelle)
associated protein 5 [Mus musculus]
         (1502 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

01598                                                                 381   e-105
17880                                                                  97   9e-25
10264                                                                  99   1e-20
19498                                                                  68   3e-11
29912                                                                  66   8e-11
03387                                                                  50   5e-06
13335                                                                  49   1e-05
28359                                                                  38   7e-05
16105                                                                  45   2e-04
03156                                                                  44   5e-04
01805                                                                  44   5e-04
01327                                                                  44   6e-04
02960                                                                  44   7e-04
27475                                                                  44   7e-04
19949                                                                  43   0.001
01768                                                                  42   0.001
00561                                                                  42   0.001
12841                                                                  40   0.009
27465                                                                  40   0.009
12806                                                                  38   0.032
30256                                                                  38   0.040
12574                                                                  37   0.042
13278                                                                  37   0.061
03395                                                                  37   0.089
15337                                                                  36   0.11 
20662                                                                  36   0.13 
30295                                                                  36   0.15 
26107                                                                  35   0.25 
17266                                                                  35   0.27 
02147                                                                  35   0.27 
02090                                                                  35   0.28 
04395                                                                  34   0.47 
19140                                                                  34   0.50 
17602                                                                  33   0.59 
01557                                                                  33   0.72 
20271                                                                  33   1.2  
15056                                                                  32   1.3  
17598                                                                  32   1.4  
14500                                                                  32   1.5  
31474                                                                  32   1.8  
31054                                                                  32   2.4  
07741                                                                  32   2.5  
25880                                                                  31   3.4  
06614                                                                  31   3.7  
06576                                                                  31   3.7  
26939                                                                  31   4.5  
11915                                                                  31   4.5  
10162                                                                  30   5.0  
15745                                                                  30   5.2  
30108                                                                  30   5.5  
11493                                                                  30   6.2  
00825                                                                  30   6.4  
14555                                                                  30   9.7  
32784                                                                  30   9.9  
>01598
          Length = 1545

 Score =  381 bits (978), Expect = e-105,   Method: Compositional matrix adjust.
 Identities = 210/531 (39%), Positives = 307/531 (57%), Gaps = 13/531 (2%)
 Frame = +1

Query: 198 IHSIAWCPLSGEDCLSISQEENSEEPDIPNGKLIAETPITKGCYLATGSKDQTIRIWSCS 257
           + S++WCP+ GE  L  SQ       D  NG    E   T GC +ATGSKD+TIR+W+ S
Sbjct: 1   VMSVSWCPVQGETFLKESQ-------DATNGLTDPERD-TGGCLIATGSKDRTIRVWTLS 156

Query: 258 RGRGVMVLKLPFLKRRSGGVDPTVKERLWLTLHWPKNQPTQLVSSCFGGELLLWDLTQSW 317
           +G+ + + KLP  +R +G  D   + ++WL +HW K+ P QLVSS  GG+LLLW L  + 
Sbjct: 157 QGKQIFMKKLPNQRREAG--DTGSRFKVWLAIHWLKSNPEQLVSSSSGGDLLLWSLRYTK 330

Query: 318 RRKYTLFSTSAEGHNHSRIVFNLCSLKTEDGKQLLLSTSMDRDVKCWDMATLECCWTLPS 377
            + Y  F TS +   H R VFN+C+   +   + L + + DR V  WD+ T+E   ++ +
Sbjct: 331 GQAYQTFQTS-DYRPHMRPVFNICASGPD--SKTLCTFAQDRQVVLWDLETMEAVASMAT 501

Query: 378 LGGFAYSLAFSPVDVGSLAIGVGDGMIRVWNTLSIKNNYDVKNFWQGVKSKVTALCWHPN 437
           LGG  Y +  SP+D G +A+GVGD MIR WN  +  N YDV   WQG+KSKVTA+ WHP 
Sbjct: 502 LGGHVYCVRTSPIDPGRVAVGVGDSMIRTWNMSNKTNPYDVTTLWQGIKSKVTAVAWHPT 681

Query: 438 KEGCLAFGTDDGKVGLYDTCSNKPPQISSTYHKKTVYRLAWGPP-VPPMSLGGEGDRPSL 496
           KEG L FGTDDG++G++D  S+K P +S+T+H +T Y + WGP  + P       D  S 
Sbjct: 682 KEGWLGFGTDDGRIGVFDVLSHKMPTLSNTFHHRTAYVVCWGPASLSPT------DGKSF 843

Query: 497 TLYSCGGEGVVLQHNPWKLS-----GEAFDINKLVRDTNSIRYKLPVHTEISWKGDGKVL 551
           +LYS  G+  +L+H+   LS       A DI + +   NS + K    TE+SW  D    
Sbjct: 844 SLYSV-GDCKILEHSSAVLSRGEKKANAIDITQKIGAVNSDQVKGLKATELSWSPDQNAA 1020

Query: 552 ALGNEDGSIEIFQVPNLRLLCTIQQHHKLVNAIVWHHEHGSRPELSC----LLASGSNNA 607
           A+G ++GS+ +  + +L+++  I+   KL+N + WH     +          LA+  N+ 
Sbjct: 1021AVGTDEGSVYVVTIQDLKIVAAIRTQQKLINCVRWHPRLTDQSPAGSPCCHWLAAAGNDQ 1200

Query: 608 VIYVHNLKAVL---ESNPESPITITEPYRTLSGHTAKITSLAWSPHHDGRLVSACYDGTA 664
           VI+V +L +V    E + E+ + +T   R LSGH+ ++T ++WSPHHD RLVS  YD  A
Sbjct: 1201VIHVVDLASVFAEREGDKETSLILTS-LRELSGHSQRVTDMSWSPHHDARLVSVGYDAEA 1377

Query: 665 QVWDALREEPLFNFRGHRGRLLCVAWSPVDPECIYSGADDFCVYRWLTSMQ 715
            VWD  +   L  F+GH GRLL   +S +DP+ + +G  D  V+ W  S Q
Sbjct: 1378FVWDVQKGTALAQFKGHMGRLLTCQFSGLDPDLVMTGGSDASVHVWRVSQQ 1530

 Score = 36.6 bits (83), Expect = 0.078,   Method: Compositional matrix adjust.
 Identities = 41/177 (23%), Positives = 76/177 (42%), Gaps = 29/177 (16%)
 Frame = +1

Query: 63   HTERVSGFT---FSHHPGQYNLCATSSDDGTVKVWDVETKTVVTEHTLHQHTISALHWSP 119
            ++++V G      S  P Q N  A  +D+G+V V  ++   +V      Q  I+ + W P
Sbjct: 955  NSDQVKGLKATELSWSPDQ-NAAAVGTDEGSVYVVTIQDLKIVAAIRTQQKLINCVRWHP 1131

Query: 120  TVKD-----------LIVSGDEKGV-------VFCYWLNRNDSQHLFTEPR-------TI 154
             + D           L  +G+++ +       VF       ++  + T  R        +
Sbjct: 1132 RLTDQSPAGSPCCHWLAAAGNDQVIHVVDLASVFAEREGDKETSLILTSLRELSGHSQRV 1311

Query: 155  FCLTCSPHHE-NLVAIGYKDGIVVIIDISKKGEVIHRLRGHDDEIHSIAWCPLSGED 210
              ++ SPHH+  LV++GY D    + D+ +KG  + + +GH   + +   C  SG D
Sbjct: 1312 TDMSWSPHHDARLVSVGY-DAEAFVWDV-QKGTALAQFKGHMGRLLT---CQFSGLD 1467
>17880
          Length = 480

 Score = 96.7 bits (239), Expect(2) = 9e-25,   Method: Compositional matrix adjust.
 Identities = 51/107 (47%), Positives = 66/107 (61%)
 Frame = -2

Query: 952  APVAGYSVWLWAVEAFAKQLCFQDQYVKAASYLLSIHKVYEAVELLKSNHLYREAIAVAK 1011
            AP+A Y  W    E ++KQL    QY KA SYLL  HK+Y A++L + + LYREA+A+A 
Sbjct: 323  APLASYETWEVVCEEYSKQLEEDGQYHKAVSYLLVSHKLYPAIDLFRRHKLYREAVALAH 144

Query: 1012 ARLRPEDPVLKELYLSWGSILERDGHYAIAAKCYLGATSAYDAAKVL 1058
             RL   DPV +++Y  W   L RDG Y  AAKCYL      +AAKV+
Sbjct: 143  VRLSLRDPVWEDIYTEWSEQLMRDGAYEQAAKCYLAMRRIQEAAKVI 3

 Score = 37.0 bits (84), Expect(2) = 9e-25,   Method: Composition-based stats.
 Identities = 14/29 (48%), Positives = 24/29 (82%)
 Frame = -3

Query: 923 QLMLWKGDLKGVLQAAAERGELTDSLVAV 951
           Q+ LWKG++ GV+Q A +RG+L+D +V++
Sbjct: 409 QMELWKGNITGVIQLARQRGQLSDWIVSL 323
>10264
          Length = 416

 Score = 99.0 bits (245), Expect = 1e-20,   Method: Compositional matrix adjust.
 Identities = 50/124 (40%), Positives = 72/124 (58%), Gaps = 8/124 (6%)
 Frame = -1

Query: 600 LASGSNNAVIYVHNLKAVL--------ESNPESPITITEPYRTLSGHTAKITSLAWSPHH 651
           LA+  N+ VI+V +L +V         E + E+ + +T   R LSGH+ ++T ++WSPHH
Sbjct: 383 LAAAGNDQVIHVVDLASVFGEMGATEREGDKETLLILTS-LRELSGHSQRVTDMSWSPHH 207

Query: 652 DGRLVSACYDGTAQVWDALREEPLFNFRGHRGRLLCVAWSPVDPECIYSGADDFCVYRWL 711
           D RLVS  YD  A VWD  +   L  F+GH GRLL   +S +DP+ + +G  D  V+ W 
Sbjct: 206 DARLVSVGYDAEAFVWDVQKGTALAQFKGHMGRLLTCQFSGLDPDLVMTGGSDASVHVWR 27

Query: 712 TSMQ 715
            S Q
Sbjct: 26  VSQQ 15

 Score = 32.0 bits (71), Expect = 1.8,   Method: Compositional matrix adjust.
 Identities = 21/85 (24%), Positives = 40/85 (47%), Gaps = 1/85 (1%)
 Frame = -1

Query: 59  ELVGHTERVSGFTFS-HHPGQYNLCATSSDDGTVKVWDVETKTVVTEHTLHQHTISALHW 117
           EL GH++RV+  ++S HH  +     +   D    VWDV+  T + +   H   +    +
Sbjct: 260 ELSGHSQRVTDMSWSPHHDARL---VSVGYDAEAFVWDVQKGTALAQFKGHMGRLLTCQF 90

Query: 118 SPTVKDLIVSGDEKGVVFCYWLNRN 142
           S    DL+++G     V  + +++ 
Sbjct: 89  SGLDPDLVMTGGSDASVHVWRVSQQ 15
>19498
          Length = 903

 Score = 68.2 bits (165), Expect = 3e-11,   Method: Compositional matrix adjust.
 Identities = 53/151 (35%), Positives = 72/151 (47%), Gaps = 6/151 (3%)
 Frame = -1

Query: 569 RLLCTIQQHHKLVNAIVWHHEHGSRPELSCLLASGSNNAVIYVHNLKAVLESNPE--SPI 626
           R+LC +  H   VN + W  E+G        LASG ++ +I +  +     S     S +
Sbjct: 813 RVLCQMDSHLGCVNCVRWS-ENGK------FLASGGDDKLIMIWQISRGFGSGKSFGSNV 655

Query: 627 TITEPYR---TLSGHTAKITSLAWSPHHDGRLVSACYDGTAQVWDALR-EEPLFNFRGHR 682
           TI E +R   TL GH   +  LAWSP  D  L S   D T  VW+AL+  E +   RGH 
Sbjct: 654 TILEHWRSVATLRGHAGDVLDLAWSPQ-DLWLASCSVDNTIVVWNALKFSEQVAVIRGHA 478

Query: 683 GRLLCVAWSPVDPECIYSGADDFCVYRWLTS 713
           G +  V W PV    + S +DD  +  W TS
Sbjct: 477 GMVKGVTWDPVG-RYLASQSDDKTLRVWRTS 388

 Score = 30.8 bits (68), Expect = 4.8,   Method: Compositional matrix adjust.
 Identities = 33/133 (24%), Positives = 57/133 (42%), Gaps = 31/133 (23%)
 Frame = -1

Query: 156 CLTCSPHHEN--LVAIGYKDGIVVIIDISK----------------KGEVIHRLRGHDDE 197
           C+ C    EN   +A G  D +++I  IS+                    +  LRGH  +
Sbjct: 780 CVNCVRWSENGKFLASGGDDKLIMIWQISRGFGSGKSFGSNVTILEHWRSVATLRGHAGD 601

Query: 198 IHSIAWCP-------LSGEDCLSI-SQEENSEEPDIPNG-----KLIAETPITKGCYLAT 244
           +  +AW P        S ++ + + +  + SE+  +  G     K +   P+  G YLA+
Sbjct: 600 VLDLAWSPQDLWLASCSVDNTIVVWNALKFSEQVAVIRGHAGMVKGVTWDPV--GRYLAS 427

Query: 245 GSKDQTIRIWSCS 257
            S D+T+R+W  S
Sbjct: 426 QSDDKTLRVWRTS 388
>29912
          Length = 510

 Score = 66.2 bits (160), Expect = 8e-11,   Method: Compositional matrix adjust.
 Identities = 48/172 (27%), Positives = 77/172 (44%), Gaps = 6/172 (3%)
 Frame = +3

Query: 542 ISWKGDGKVLALGNEDGSIEIFQVPNLRLLCTIQQHHKLVNAIVWHHEHGSRPELSCLLA 601
           +SW  +G  LALG   G ++++ V   + L T+  H   V ++ W+         S +++
Sbjct: 27  VSWIKEGNYLALGTSTGEVQVWDVTQQKKLRTMAGHAARVGSLSWN---------SFIVS 179

Query: 602 SGSNNAVIYVHNLKAVLESNPESPITITEPYRTLSGHTAKITSLAWSPHHDGR-LVSACY 660
           SGS +  I+ H+++                  TLSGH+ ++  L WSP  DG+ L S   
Sbjct: 180 SGSRSGNIHHHDVRVA-----------DHHVGTLSGHSQEVCGLRWSP--DGKYLASGAN 320

Query: 661 DGTAQVWDAL-----REEPLFNFRGHRGRLLCVAWSPVDPECIYSGADDFCV 707
           D    VW A        +PL  F  H+  +  +AW P  P  + SG  D  +
Sbjct: 321 DNLLCVWPAQVTGGNSTQPLHTFSQHQAAVKALAWCPWQPSXLASGGGDVLI 476

 Score = 32.7 bits (73), Expect = 1.0,   Method: Compositional matrix adjust.
 Identities = 31/133 (23%), Positives = 55/133 (41%), Gaps = 7/133 (5%)
 Frame = +3

Query: 80  NLCATSSDDGTVKVWDVETKTVVTEHTLHQHTISALHWSPTVKDLIVSGDEKGVVFCYWL 139
           N  A  +  G V+VWDV  +  +     H   + +L W+  +   + SG   G +  + +
Sbjct: 48  NYLALGTSTGEVQVWDVTQQKKLRTMAGHAARVGSLSWNSFI---VSSGSRSGNIHHHDV 218

Query: 140 NRNDSQHLFT---EPRTIFCLTCSPHHENLVAIGYKDGIVVIIDISKKG----EVIHRLR 192
              D  H+ T     + +  L  SP  + L A G  D ++ +      G    + +H   
Sbjct: 219 RVAD-HHVGTLSGHSQEVCGLRWSPDGKYL-ASGANDNLLCVWPAQVTGGNSTQPLHTFS 392

Query: 193 GHDDEIHSIAWCP 205
            H   + ++AWCP
Sbjct: 393 QHQAAVKALAWCP 431
>03387
          Length = 1891

 Score = 50.4 bits (119), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 40/157 (25%), Positives = 69/157 (43%), Gaps = 11/157 (7%)
 Frame = +1

Query: 60  LVGHTERVSGFTFSHHPGQYNLCATSSDDGTVKVWDVETKT----VVTEHTL---HQHTI 112
           L GH +   G+  S +P       ++SDD T+ +WD+ +      VV  HT+   H   +
Sbjct: 349 LKGHQKE--GYGLSWNPNLNGHLLSASDDHTICLWDINSTQRESRVVDAHTIFTGHTSVV 522

Query: 113 SALHWSPTVKDLI--VSGDEKGVVFCYWLNRNDSQHLFTEPRT--IFCLTCSPHHENLVA 168
             + W    + L   V+ D+K +++    N         +  T  + CL+ +P+ E ++A
Sbjct: 523 EDVAWHLLHESLFGSVADDQKLMIWDTRSNTTSKPSHVVDAHTAEVNCLSFNPYSEFILA 702

Query: 169 IGYKDGIVVIIDISKKGEVIHRLRGHDDEIHSIAWCP 205
            G  D  V + D+      +H    H DEI  + W P
Sbjct: 703 TGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSP 813

 Score = 46.2 bits (108), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 58/264 (21%), Positives = 101/264 (38%), Gaps = 19/264 (7%)
 Frame = +1

Query: 423 QGVKSKVTALCWHPNKEGCLAFGTDDGKVGLYDTCSNKPPQISSTYHKKTVYRLAWGPPV 482
           +G + +   L W+PN  G L   +DD  + L+D        I+ST  +  V         
Sbjct: 352 KGHQKEGYGLSWNPNLNGHLLSASDDHTICLWD--------INSTQRESRVVD------- 486

Query: 483 PPMSLGGEGDRPSLTLYSCGGEGVVLQHNPWKLSGEAF------DINKLVRDTNSIRYKL 536
                       + T+++  G   V++   W L  E+       D   ++ DT S     
Sbjct: 487 ------------AHTIFT--GHTSVVEDVAWHLLHESLFGSVADDQKLMIWDTRSNTTSK 624

Query: 537 PVHTEISWKGDGK----------VLALGNEDGSIEIFQVPNLRL-LCTIQQHHKLVNAIV 585
           P H   +   +            +LA G+ D ++ ++ + NL+L L + + H   +  + 
Sbjct: 625 PSHVVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQ 804

Query: 586 WHHEHGSRPELSCLLASGSNNAVIYVHNLKAVLESNPESPITITEPYRTL--SGHTAKIT 643
           W       P    +LAS   +  ++V +L  + E           P       GHTAKI+
Sbjct: 805 W------SPHNETILASSGTDRRLHVWDLSKIGEEQLPEDAEDGPPELLFIHGGHTAKIS 966

Query: 644 SLAWSPHHDGRLVSACYDGTAQVW 667
             +W+P+    + S   D   QVW
Sbjct: 967 DFSWNPNEPWIVCSVSEDNIMQVW 1038

 Score = 45.1 bits (105), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 32/136 (23%), Positives = 62/136 (45%), Gaps = 2/136 (1%)
 Frame = +1

Query: 577 HHKLVNAIVWHHEHGSRPELSCLLASGSNNAVIYVHNLKAVLESNPESPITITEPYRTLS 636
           H  +V  + WH  H S      L  S +++  + + + ++          T ++P   + 
Sbjct: 508 HTSVVEDVAWHLLHES------LFGSVADDQKLMIWDTRSN---------TTSKPSHVVD 642

Query: 637 GHTAKITSLAWSPHHDGRLVSACYDGTAQVWDALR--EEPLFNFRGHRGRLLCVAWSPVD 694
            HTA++  L+++P+ +  L +   D T  +WD LR  +  L +F  H+  +  V WSP +
Sbjct: 643 AHTAEVNCLSFNPYSEFILATGSADKTVALWD-LRNLKLKLHSFESHKDEIFQVQWSPHN 819

Query: 695 PECIYSGADDFCVYRW 710
              + S   D  ++ W
Sbjct: 820 ETILASSGTDRRLHVW 867

 Score = 44.3 bits (103), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 38/136 (27%), Positives = 61/136 (44%), Gaps = 9/136 (6%)
 Frame = +1

Query: 594 PELSCLLASGSNNAVIYVHNLKAVLESNPESPITITE--PYRTLSGHTAKITSLAWSPHH 651
           P+  C++A+ + ++ + V +       +P  P    E  P   L GH  +   L+W+P+ 
Sbjct: 232 PQNPCIIATKTPSSDVLVFDYT----KHPSKPDPSGECIPELRLKGHQKEGYGLSWNPNL 399

Query: 652 DGRLVSACYDGTAQVWD---ALREEPLFN----FRGHRGRLLCVAWSPVDPECIYSGADD 704
           +G L+SA  D T  +WD     RE  + +    F GH   +  VAW  +      S ADD
Sbjct: 400 NGHLLSASDDHTICLWDINSTQRESRVVDAHTIFTGHTSVVEDVAWHLLHESLFGSVADD 579

Query: 705 FCVYRWLTSMQDHSRP 720
             +  W T     S+P
Sbjct: 580 QKLMIWDTRSNTTSKP 627

 Score = 39.7 bits (91), Expect = 0.009,   Method: Compositional matrix adjust.
 Identities = 29/132 (21%), Positives = 53/132 (40%), Gaps = 14/132 (10%)
 Frame = +1

Query: 593 RPELSCLLASGSNNAVIYVHNLKAVLESNPESPITITEPYRTLSGHTAKITSLAWSPHHD 652
            P    +LA+GS +  + + +L+            +     +   H  +I  + WSPH++
Sbjct: 676 NPYSEFILATGSADKTVALWDLR-----------NLKLKLHSFESHKDEIFQVQWSPHNE 822

Query: 653 GRLVSACYDGTAQVWDALR--------------EEPLFNFRGHRGRLLCVAWSPVDPECI 698
             L S+  D    VWD  +               E LF   GH  ++   +W+P +P  +
Sbjct: 823 TILASSGTDRRLHVWDLSKIGEEQLPEDAEDGPPELLFIHGGHTAKISDFSWNPNEPWIV 1002

Query: 699 YSGADDFCVYRW 710
            S ++D  +  W
Sbjct: 1003CSVSEDNIMQVW 1038

 Score = 37.7 bits (86), Expect = 0.038,   Method: Compositional matrix adjust.
 Identities = 46/218 (21%), Positives = 89/218 (40%), Gaps = 23/218 (10%)
 Frame = +1

Query: 289 LHWPKNQPTQLVSSCFGGELLLWDLTQSWRRK-----YTLFSTSAEGHNHSRIVFNLCSL 343
           L W  N    L+S+     + LWD+  + R       +T+F+       H+ +V ++   
Sbjct: 379 LSWNPNLNGHLLSASDDHTICLWDINSTQRESRVVDAHTIFT------GHTSVVEDVAWH 540

Query: 344 KTEDGKQLLLSTSMDRDVKCWDMATLECCWTLPSLGGFAYS-----LAFSPVDVGSLAIG 398
              +   L  S + D+ +  WD  T     + PS    A++     L+F+P     LA G
Sbjct: 541 LLHES--LFGSVADDQKLMIWD--TRSNTTSKPSHVVDAHTAEVNCLSFNPYSEFILATG 708

Query: 399 VGDGMIRVWNTLSIKNNYDVKNFWQGVKSKVTALCWHPNKEGCLAFGTDDGKVGLYD--- 455
             D  + +W+  ++K    + +F +  K ++  + W P+ E  LA    D ++ ++D   
Sbjct: 709 SADKTVALWDLRNLK--LKLHSF-ESHKDEIFQVQWSPHNETILASSGTDRRLHVWDLSK 879

Query: 456 --------TCSNKPPQISSTY--HKKTVYRLAWGPPVP 483
                      + PP++   +  H   +   +W P  P
Sbjct: 880 IGEEQLPEDAEDGPPELLFIHGGHTAKISDFSWNPNEP 993

 Score = 34.7 bits (78), Expect = 0.27,   Method: Compositional matrix adjust.
 Identities = 31/118 (26%), Positives = 47/118 (39%), Gaps = 6/118 (5%)
 Frame = +1

Query: 382 AYSLAFSPVDVGSLAIGVGDGMIRVWNTLSIKNN---YDVKNFWQGVKSKVTALCWHPNK 438
            Y L+++P   G L     D  I +W+  S +      D    + G  S V  + WH   
Sbjct: 370 GYGLSWNPNLNGHLLSASDDHTICLWDINSTQRESRVVDAHTIFTGHTSVVEDVAWHLLH 549

Query: 439 EGCLAFGTDDGKVGLYDTCSN---KPPQISSTYHKKTVYRLAWGPPVPPMSLGGEGDR 493
           E       DD K+ ++DT SN   KP  +    H   V  L++ P    +   G  D+
Sbjct: 550 ESLFGSVADDQKLMIWDTRSNTTSKPSHVVDA-HTAEVNCLSFNPYSEFILATGSADK 720
>13335
          Length = 863

 Score = 48.9 bits (115), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 76/285 (26%), Positives = 108/285 (37%), Gaps = 9/285 (3%)
 Frame = +1

Query: 91  VKVWDVETKTVVTEHTLHQH----TISALHWSPTVKDLIVSGDEKGVVFCYW--LNRNDS 144
           V VWDV+T ++  E+   QH    +I    +SP+   L+   D+  +  C W    +   
Sbjct: 4   VIVWDVKTGSIKGEY---QHASKSSIRVCKFSPSSSHLVSGSDDDTI--CMWEVATQKLV 168

Query: 145 QHLFTEPRTIFCLTCSPHHENLVAIGYKDGIVVIIDISKKGEVIH---RLRGHDDEIHSI 201
           +       ++  L  SP+   LV+ G  +G + + D S  G   H   R+  HD  +   
Sbjct: 169 RSYVGHEDSVMALAYSPNGHYLVS-GSPNGDLYVWDASF-GHCRHLTLRVDAHDLGVTCC 342

Query: 202 AWCPLSGEDCLSISQEENSEEPDIPNGKLIAETPITKGCYLATGSKDQTIRIWSCSRGRG 261
            + P  G  C                    AE   T    LATG KD  I++W+ S   G
Sbjct: 343 EFSPTFGTAC--------------------AENSSTCNLLLATGGKDNLIKLWTFSAQVG 462

Query: 262 VMVLKLPFLKRRSGGVDPTVKERLWLTLHWPKNQPTQLVSSCFGGELLLWDLTQSWRRKY 321
              + L      SG  D  +                 L S  F   + LWD      +  
Sbjct: 463 SPEVTLQCRDILSGHSDLVMACAF-------SPSSALLASGSFDKSVRLWDSV----KGV 609

Query: 322 TLFSTSAEGHNHSRIVFNLCSLKTEDGKQLLLSTSMDRDVKCWDM 366
            LFS  A    HSR V   C   + DG  LL S SMDR +K W +
Sbjct: 610 ALFSIEA---CHSRFV--TCCAFSIDG-TLLASGSMDRIIKIWKL 726
>28359
          Length = 444

 Score = 37.7 bits (86), Expect(2) = 7e-05,   Method: Composition-based stats.
 Identities = 15/35 (42%), Positives = 24/35 (68%)
 Frame = -3

Query: 156 CLTCSPHHENLVAIGYKDGIVVIIDISKKGEVIHR 190
           CL+CSPH    VA+G K G+V ++D++ +G+   R
Sbjct: 208 CLSCSPHIPLNVAVGTKQGVVFVLDLNNQGKFCIR 104

 Score = 28.1 bits (61), Expect(2) = 7e-05,   Method: Composition-based stats.
 Identities = 7/20 (35%), Positives = 16/20 (80%)
 Frame = -2

Query: 186 EVIHRLRGHDDEIHSIAWCP 205
           ++++++RG DD+   ++WCP
Sbjct: 119 KILYKIRGQDDDGCDVSWCP 60
>16105
          Length = 960

 Score = 45.4 bits (106), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 35/127 (27%), Positives = 58/127 (45%), Gaps = 7/127 (5%)
 Frame = -2

Query: 76  PGQYNLCATSSDDGTVKVWDVETKTVVTEHT-------LHQHTISALHWSPTVKDLIVSG 128
           P   N+ A++SDD TVKVW +    +VT  T        HQ     + W P+ ++++VS 
Sbjct: 545 PHNDNVIASASDDCTVKVWQIPDSGLVTNLTDPVVDLVGHQKRCCLIVWHPSAQNVLVSA 366

Query: 129 DEKGVVFCYWLNRNDSQHLFTEPRTIFCLTCSPHHENLVAIGYKDGIVVIIDISKKGEVI 188
                +  + +   +       P  I+C++ + +   LV    KD  + IID S  G V+
Sbjct: 365 GADNKILFWNVGTGEPMLEVDVPDMIYCMSFNFNGSRLVCT-CKDKKLRIID-SHSGAVL 192

Query: 189 HRLRGHD 195
              + HD
Sbjct: 191 KEGKCHD 171

 Score = 43.1 bits (100), Expect = 9e-04,   Method: Compositional matrix adjust.
 Identities = 21/83 (25%), Positives = 35/83 (42%), Gaps = 7/83 (8%)
 Frame = -2

Query: 635 LSGHTAKITSLAWSPHHDGRLVSACYDGTAQVWDALRE-------EPLFNFRGHRGRLLC 687
           ++GH   +  + W PH+D  + SA  D T +VW            +P+ +  GH+ R   
Sbjct: 587 VAGHKGAVLDIQWCPHNDNVIASASDDCTVKVWQIPDSGLVTNLTDPVVDLVGHQKRCCL 408

Query: 688 VAWSPVDPECIYSGADDFCVYRW 710
           + W P     + S   D  +  W
Sbjct: 407 IVWHPSAQNVLVSAGADNKILFW 339

 Score = 36.6 bits (83), Expect = 0.087,   Method: Compositional matrix adjust.
 Identities = 29/109 (26%), Positives = 44/109 (40%), Gaps = 15/109 (13%)
 Frame = -2

Query: 594 PELSCLLASGSNNAVIYVHNLKAVLESNPESPIT--ITEPYRTLSGHTAKITSLAWSPHH 651
           P    ++AS S++  + V  +       P+S +   +T+P   L GH  +   + W P  
Sbjct: 545 PHNDNVIASASDDCTVKVWQI-------PDSGLVTNLTDPVVDLVGHQKRCCLIVWHPSA 387

Query: 652 DGRLVSACYDGTAQVWDALREEPL-------------FNFRGHRGRLLC 687
              LVSA  D     W+    EP+             FNF G   RL+C
Sbjct: 386 QNVLVSAGADNKILFWNVGTGEPMLEVDVPDMIYCMSFNFNG--SRLVC 246
>03156
          Length = 1014

 Score = 43.9 bits (102), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 40/165 (24%), Positives = 70/165 (42%), Gaps = 16/165 (9%)
 Frame = +1

Query: 57  VGELVGHTERVSGFTFSHHPGQYNLCATSSDDGTVKVWDVETKTVVTEHTLHQHTISALH 116
           + + +GH   V+     H      L  + S D TV++WDVET   + ++ + Q+ ++ + 
Sbjct: 160 IRDFIGHDMVVTAI---HLNTDNTLLCSGSRDNTVRIWDVETGACLRQNNIPQNLVTDVK 330

Query: 117 WSPTVKDLIVSGDEKGVVFCYWLNRNDSQHL-----FTEPRTI-----------FCLTCS 160
           W P    +I +G++K V         DS+ L     FT+ + I           FCLTCS
Sbjct: 331 WLPGSHLIIQAGEDKEVRI------YDSRTLGIVRSFTKKQYIQMSCDVTADGQFCLTCS 492

Query: 161 PHHENLVAIGYKDGIVVIIDISKKGEVIHRLRGHDDEIHSIAWCP 205
                    G       +  +S  G + +  +GH + I +  + P
Sbjct: 493 N------GFGGNGCEATLWQLS-DGSIQNEFKGHREAIEACLFLP 606

 Score = 38.9 bits (89), Expect = 0.014,   Method: Compositional matrix adjust.
 Identities = 61/265 (23%), Positives = 97/265 (36%), Gaps = 46/265 (17%)
 Frame = +1

Query: 181 ISKKGEVIHRLRGHDDEIHSIAW---C----PLSGEDCLSISQEENSEEPDIPNGKLIAE 233
           +SK G +  R  GHD EI  + +   C      S +  + + Q  NS       G  +  
Sbjct: 13  LSKMGRLEDRWTGHDREITKVCYGASCNGMFSASRDKTIKMWQRGNSHSIRDFIGHDMVV 192

Query: 234 TPI---TKGCYLATGSKDQTIRIW-----SCSRGRGV---MVLKLPFL------------ 270
           T I   T    L +GS+D T+RIW     +C R   +   +V  + +L            
Sbjct: 193 TAIHLNTDNTLLCSGSRDNTVRIWDVETGACLRQNNIPQNLVTDVKWLPGSHLIIQAGED 372

Query: 271 ------KRRSGGVDPTVKERLWLTLHWPKNQPTQLVSSC---FGG---ELLLWDLTQSWR 318
                   R+ G+  +  ++ ++ +        Q   +C   FGG   E  LW L+    
Sbjct: 373 KEVRIYDSRTLGIVRSFTKKQYIQMSCDVTADGQFCLTCSNGFGGNGCEATLWQLSDG-- 546

Query: 319 RKYTLFSTSAEGHNHSRIVFNLCSLKTEDGKQLLLSTSMDRDVKCWDMATLECCW--TLP 376
                 S   E   H   +     L +     L+ + S D  V+ W+M T EC       
Sbjct: 547 ------SIQNEFKGHREAIEACLFLPSNQDMTLIATASRDCSVRVWNMFTKECVCEQNFE 708

Query: 377 SLGGFAYSLAF--SPVDVGSLAIGV 399
             G     +A+    V VG+  +GV
Sbjct: 709 GTGPLTSMIAYGDGSVLVGTFNLGV 783

 Score = 31.6 bits (70), Expect = 2.4,   Method: Compositional matrix adjust.
 Identities = 17/52 (32%), Positives = 24/52 (46%)
 Frame = +1

Query: 56  VVGELVGHTERVSGFTFSHHPGQYNLCATSSDDGTVKVWDVETKTVVTEHTL 107
           +  E  GH E +    F        L AT+S D +V+VW++ TK  V E   
Sbjct: 550 IQNEFKGHREAIEACLFLPSNQDMTLIATASRDCSVRVWNMFTKECVCEQNF 705
>01805
          Length = 2124

 Score = 43.9 bits (102), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 21/75 (28%), Positives = 36/75 (48%)
 Frame = -1

Query: 633 RTLSGHTAKITSLAWSPHHDGRLVSACYDGTAQVWDALREEPLFNFRGHRGRLLCVAWSP 692
            +++GHT  +  L+W+ +    L SA  D T  +WD    +   NF  H   + C  W P
Sbjct: 594 ESVTGHTQAVLDLSWNRNARHVLASASADTTVALWDLSEGKMAMNFTQHSREVQCCNWHP 415

Query: 693 VDPECIYSGADDFCV 707
            + + + +G+ D  V
Sbjct: 414 QEEQTLLTGSFDNTV 370

 Score = 34.7 bits (78), Expect = 0.31,   Method: Compositional matrix adjust.
 Identities = 35/171 (20%), Positives = 72/171 (42%), Gaps = 1/171 (0%)
 Frame = -1

Query: 541 EISWKGDGK-VLALGNEDGSIEIFQVPNLRLLCTIQQHHKLVNAIVWHHEHGSRPELSCL 599
           ++SW  + + VLA  + D ++ ++ +   ++     QH + V    WH      P+    
Sbjct: 561 DLSWNRNARHVLASASADTTVALWDLSEGKMAMNFTQHSREVQCCNWH------PQEEQT 400

Query: 600 LASGSNNAVIYVHNLKAVLESNPESPITITEPYRTLSGHTAKITSLAWSPHHDGRLVSAC 659
           L +GS +  + V + +        S  T  + + T+ G   K     W+ H+  +L++  
Sbjct: 399 LLTGSFDNTVKVVDCR--------SAETCHKSW-TVEGEVEKA---VWNHHNPLQLLACT 256

Query: 660 YDGTAQVWDALREEPLFNFRGHRGRLLCVAWSPVDPECIYSGADDFCVYRW 710
             G    +D   E+P+F+   H   +  V  S   P  + + ++D  +  W
Sbjct: 255 DKGMVYCFDIRHEKPVFSVGAHSSCVTGVCLSSQIPGLMITTSEDKTMKVW 103

 Score = 32.3 bits (72), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 43/180 (23%), Positives = 73/180 (40%)
 Frame = -1

Query: 287 LTLHWPKNQPTQLVSSCFGGELLLWDLTQSWRRKYTLFSTSAEGHNHSRIVFNLCSLKTE 346
           L L W +N    L S+     + LWDL++    K  +  T      HSR V   C+   +
Sbjct: 564 LDLSWNRNARHVLASASADTTVALWDLSEG---KMAMNFTQ-----HSREV-QCCNWHPQ 412

Query: 347 DGKQLLLSTSMDRDVKCWDMATLECCWTLPSLGGFAYSLAFSPVDVGSLAIGVGDGMIRV 406
           + +Q LL+ S D  VK  D  + E C    ++ G      ++  +   L      GM+  
Sbjct: 411 E-EQTLLTGSFDNTVKVVDCRSAETCHKSWTVEGEVEKAVWNHHNPLQLLACTDKGMVYC 235

Query: 407 WNTLSIKNNYDVKNFWQGVKSKVTALCWHPNKEGCLAFGTDDGKVGLYDTCSNKPPQISS 466
           ++    K  + V        S VT +C      G +   ++D  + ++D   +KP  + S
Sbjct: 234 FDIRHEKPVFSVG----AHSSCVTGVCLSSQIPGLMITTSEDKTMKVWDIQDDKPTHVFS 67

 Score = 32.0 bits (71), Expect = 2.1,   Method: Compositional matrix adjust.
 Identities = 17/75 (22%), Positives = 36/75 (48%)
 Frame = -1

Query: 60  LVGHTERVSGFTFSHHPGQYNLCATSSDDGTVKVWDVETKTVVTEHTLHQHTISALHWSP 119
           + GHT+ V   +++ +    ++ A++S D TV +WD+    +    T H   +   +W P
Sbjct: 588 VTGHTQAVLDLSWNRNA--RHVLASASADTTVALWDLSEGKMAMNFTQHSREVQCCNWHP 415

Query: 120 TVKDLIVSGDEKGVV 134
             +  +++G     V
Sbjct: 414 QEEQTLLTGSFDNTV 370
>01327
          Length = 2215

 Score = 43.5 bits (101), Expect = 6e-04,   Method: Compositional matrix adjust.
 Identities = 40/165 (24%), Positives = 70/165 (42%), Gaps = 16/165 (9%)
 Frame = +3

Query: 57  VGELVGHTERVSGFTFSHHPGQYNLCATSSDDGTVKVWDVETKTVVTEHTLHQHTISALH 116
           + + +GH   V+     H      L  + S D TV++WDVET   + ++ + Q+ ++ + 
Sbjct: 270 IRDFIGHDMVVTAI---HLNTDNTLLCSGSRDNTVRIWDVETGACLRQNNIPQNLVTDVK 440

Query: 117 WSPTVKDLIVSGDEKGVVFCYWLNRNDSQHL-----FTEPRTI-----------FCLTCS 160
           W P    +I +G++K V         DS+ L     FT+ + I           FCLTCS
Sbjct: 441 WLPGSHLIIQAGEDKEVRI------YDSRTLGIVRSFTKKQYIQMSCDVTADGQFCLTCS 602

Query: 161 PHHENLVAIGYKDGIVVIIDISKKGEVIHRLRGHDDEIHSIAWCP 205
                    G       +  +S  G + +  +GH + I +  + P
Sbjct: 603 N------GFGGNGCEATLWQLS-DGSIQNEFKGHREAIEACLFLP 716

 Score = 40.8 bits (94), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 63/276 (22%), Positives = 97/276 (35%), Gaps = 46/276 (16%)
 Frame = +3

Query: 170 GYKDGIVVIIDISKKGEVIHRLRGHDDEIHSIAW---C----PLSGEDCLSISQEENSEE 222
           G KD  VV+ D  + G +  R  GHD EI  + +   C      S +  + + Q  NS  
Sbjct: 93  GSKDKSVVLYDY-QNGRLEDRWTGHDREITKVCYGASCNGMFSASRDKTIKMWQRGNSHS 269

Query: 223 PDIPNGKLIAETPI---TKGCYLATGSKDQTIRIWSCSRGRGVMVLKLP----------- 268
                G  +  T I   T    L +GS+D T+RIW    G  +    +P           
Sbjct: 270 IRDFIGHDMVVTAIHLNTDNTLLCSGSRDNTVRIWDVETGACLRQNNIPQNLVTDVKWLP 449

Query: 269 ---------------FLKRRSGGVDPTVKERLWLTLHWPKNQPTQLVSSC---FGG---E 307
                              R+ G+  +  ++ ++ +        Q   +C   FGG   E
Sbjct: 450 GSHLIIQAGEDKEVRIYDSRTLGIVRSFTKKQYIQMSCDVTADGQFCLTCSNGFGGNGCE 629

Query: 308 LLLWDLTQSWRRKYTLFSTSAEGHNHSRIVFNLCSLKTEDGKQLLLSTSMDRDVKCWDMA 367
             LW L+          S   E   H   +     L +     L+ + S D  V+ W+M 
Sbjct: 630 ATLWQLSDG--------SIQNEFKGHREAIEACLFLPSNQDMTLIATASRDCSVRVWNMF 785

Query: 368 TLECCW--TLPSLGGFAYSLAF--SPVDVGSLAIGV 399
           T EC         G     +A+    V VG+  +GV
Sbjct: 786 TKECVCEQNFEGTGPLTSMIAYGDGSVLVGTFNLGV 893

 Score = 31.6 bits (70), Expect = 2.7,   Method: Compositional matrix adjust.
 Identities = 17/52 (32%), Positives = 24/52 (46%)
 Frame = +3

Query: 56  VVGELVGHTERVSGFTFSHHPGQYNLCATSSDDGTVKVWDVETKTVVTEHTL 107
           +  E  GH E +    F        L AT+S D +V+VW++ TK  V E   
Sbjct: 660 IQNEFKGHREAIEACLFLPSNQDMTLIATASRDCSVRVWNMFTKECVCEQNF 815
>02960
          Length = 1577

 Score = 43.5 bits (101), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 23/71 (32%), Positives = 35/71 (49%), Gaps = 1/71 (1%)
 Frame = +2

Query: 635  LSGHTAKITSLAWSPHHDGRLVSACYDGTAQVWDALR-EEPLFNFRGHRGRLLCVAWSPV 693
             + HT  +T + WSP  +   +S  YD   ++WD    +  L++   H  R+L V WS  
Sbjct: 1202 FTSHTGWVTGVDWSPTREHLFLSGSYDNVLKLWDTRSPKATLYDMNWHEDRILAVDWSI- 1378

Query: 694  DPECIYSGADD 704
             PE + SG  D
Sbjct: 1379 -PELLLSGGVD 1408

 Score = 38.9 bits (89), Expect = 0.014,   Method: Compositional matrix adjust.
 Identities = 29/91 (31%), Positives = 44/91 (48%), Gaps = 8/91 (8%)
 Frame = +2

Query: 630 EPYRTLSGHTAKITSLAWSPHHDGR----LVSACYDGTAQVWDALRE----EPLFNFRGH 681
           E   T+ GHT+ +  +AW  H +       V+  +D TA VW   RE    +   + RGH
Sbjct: 575 EAIMTIPGHTSPVKCVAWIKHDESSGVSTFVTGSHDQTALVWQWQRETNEVDCRLSCRGH 754

Query: 682 RGRLLCVAWSPVDPECIYSGADDFCVYRWLT 712
              + CVA SP D + + +G+ D  +  W T
Sbjct: 755 AASVDCVAVSP-DSQQMCTGSWDKMLKLWST 844

 Score = 35.4 bits (80), Expect = 0.16,   Method: Compositional matrix adjust.
 Identities = 36/154 (23%), Positives = 65/154 (42%)
 Frame = +2

Query: 352  LLSTSMDRDVKCWDMATLECCWTLPSLGGFAYSLAFSPVDVGSLAIGVGDGMIRVWNTLS 411
            ++++S D  ++ WD+ T +   +L         +A+SP+    L  G  D  +R+ +   
Sbjct: 1001 VVTSSWDHSLRLWDLHTAQQT-SLIQGSKAVLDVAYSPLS-HMLITGSADRHVRLVDP-R 1171

Query: 412  IKNNYDVKNFWQGVKSKVTALCWHPNKEGCLAFGTDDGKVGLYDTCSNKPPQISSTYHKK 471
                  VK  +      VT + W P +E     G+ D  + L+DT S K       +H+ 
Sbjct: 1172 CSEGETVKCAFTSHTGWVTGVDWSPTREHLFLSGSYDNVLKLWDTRSPKATLYDMNWHED 1351

Query: 472  TVYRLAWGPPVPPMSLGGEGDRPSLTLYSCGGEG 505
             +  + W  P   +S GG  ++  +  YS    G
Sbjct: 1352 RILAVDWSIPELLLS-GGVDNKLHVFSYSSAKLG 1450

 Score = 35.0 bits (79), Expect = 0.21,   Method: Compositional matrix adjust.
 Identities = 23/74 (31%), Positives = 40/74 (54%), Gaps = 1/74 (1%)
 Frame = +2

Query: 631  PYRTLSGHTAKITSLAW-SPHHDGRLVSACYDGTAQVWDALREEPLFNFRGHRGRLLCVA 689
            P  TLSGH   ++++ W  PH   R+V++ +D + ++WD    +     +G +  +L VA
Sbjct: 935  PVLTLSGHAEAVSAVRWLDPH---RVVTSSWDHSLRLWDLHTAQQTSLIQGSKA-VLDVA 1102

Query: 690  WSPVDPECIYSGAD 703
            +SP+    I   AD
Sbjct: 1103 YSPLSHMLITGSAD 1144

 Score = 32.0 bits (71), Expect = 1.8,   Method: Compositional matrix adjust.
 Identities = 14/40 (35%), Positives = 21/40 (52%)
 Frame = +2

Query: 651 HDGRLVSACYDGTAQVWDALREEPLFNFRGHRGRLLCVAW 690
           H G  +S  YD T ++W + + E +    GH   + CVAW
Sbjct: 512 HTGXXLSGSYDNTVRLW-STKGEAIMTIPGHTSPVKCVAW 628
>27475
          Length = 369

 Score = 43.5 bits (101), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 23/71 (32%), Positives = 35/71 (49%), Gaps = 1/71 (1%)
 Frame = +2

Query: 635 LSGHTAKITSLAWSPHHDGRLVSACYDGTAQVWDALR-EEPLFNFRGHRGRLLCVAWSPV 693
            + HT  +T + WSP  +   +S  YD   ++WD    +  L++   H  R+L V WS  
Sbjct: 56  FTSHTGWVTGVDWSPTREHLFLSGSYDNVLKLWDTRSPKATLYDMNWHEDRILAVDWSI- 232

Query: 694 DPECIYSGADD 704
            PE + SG  D
Sbjct: 233 -PELLLSGGVD 262

 Score = 30.4 bits (67), Expect = 5.5,   Method: Compositional matrix adjust.
 Identities = 18/65 (27%), Positives = 29/65 (44%)
 Frame = +2

Query: 429 VTALCWHPNKEGCLAFGTDDGKVGLYDTCSNKPPQISSTYHKKTVYRLAWGPPVPPMSLG 488
           VT + W P +E     G+ D  + L+DT S K       +H+  +  + W   +P + L 
Sbjct: 77  VTGVDWSPTREHLFLSGSYDNVLKLWDTRSPKATLYDMNWHEDRILAVDWS--IPELLLS 250

Query: 489 GEGDR 493
           G  D 
Sbjct: 251 GGVDN 265
>19949
          Length = 903

 Score = 42.7 bits (99), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 33/102 (32%), Positives = 50/102 (49%)
 Frame = +2

Query: 354 STSMDRDVKCWDMATLECCWTLPSLGGFAYSLAFSPVDVGSLAIGVGDGMIRVWNTLSIK 413
           S SMD +VK WD+    C +T     G    L FSP D   +A    DG++++W+  + K
Sbjct: 44  SGSMDCNVKLWDIRRKGCIYTYKGHTGCVCCLRFSP-DGRWIASASEDGLVKLWDLTAGK 220

Query: 414 NNYDVKNFWQGVKSKVTALCWHPNKEGCLAFGTDDGKVGLYD 455
              D+K      +  V  + +HP+ E  LA G+ D  V  +D
Sbjct: 221 LLTDLKLH----RDAVNTIEFHPH-EFLLASGSADRTVKFWD 331

 Score = 35.4 bits (80), Expect = 0.19,   Method: Compositional matrix adjust.
 Identities = 20/69 (28%), Positives = 35/69 (50%)
 Frame = +2

Query: 642 ITSLAWSPHHDGRLVSACYDGTAQVWDALREEPLFNFRGHRGRLLCVAWSPVDPECIYSG 701
           + SL + P+      S   D   ++WD  R+  ++ ++GH G + C+ +SP D   I S 
Sbjct: 2   VKSLDFHPY-GAYTASGSMDCNVKLWDIRRKGCIYTYKGHTGCVCCLRFSP-DGRWIASA 175

Query: 702 ADDFCVYRW 710
           ++D  V  W
Sbjct: 176 SEDGLVKLW 202

 Score = 35.0 bits (79), Expect = 0.21,   Method: Compositional matrix adjust.
 Identities = 26/86 (30%), Positives = 43/86 (50%), Gaps = 1/86 (1%)
 Frame = +2

Query: 547 DGKVLALGNEDGSIEIFQVPNLRLLCTIQQHHKLVNAIVWH-HEHGSRPELSCLLASGSN 605
           DG+ +A  +EDG ++++ +   +LL  ++ H   VN I +H HE         LLASGS 
Sbjct: 152 DGRWIASASEDGLVKLWDLTAGKLLTDLKLHRDAVNTIEFHPHEF--------LLASGSA 307

Query: 606 NAVIYVHNLKAVLESNPESPITITEP 631
           +  +   +L+          I+ TEP
Sbjct: 308 DRTVKFWDLETF------QLISTTEP 367

 Score = 32.7 bits (73), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 19/58 (32%), Positives = 34/58 (58%)
 Frame = +2

Query: 62  GHTERVSGFTFSHHPGQYNLCATSSDDGTVKVWDVETKTVVTEHTLHQHTISALHWSP 119
           GHT  V    FS   G++   A++S+DG VK+WD+    ++T+  LH+  ++ + + P
Sbjct: 113 GHTGCVCCLRFSPD-GRW--IASASEDGLVKLWDLTAGKLLTDLKLHRDAVNTIEFHP 277

 Score = 32.0 bits (71), Expect = 2.2,   Method: Compositional matrix adjust.
 Identities = 19/65 (29%), Positives = 37/65 (56%)
 Frame = +2

Query: 55  RVVGELVGHTERVSGFTFSHHPGQYNLCATSSDDGTVKVWDVETKTVVTEHTLHQHTISA 114
           +++ +L  H + V+   F  HP ++ L A+ S D TVK WD+ET  +++      ++I +
Sbjct: 218 KLLTDLKLHRDAVNTIEF--HPHEF-LLASGSADRTVKFWDLETFQLISTTEPEANSIRS 388

Query: 115 LHWSP 119
           + + P
Sbjct: 389 ILFHP 403
>01768
          Length = 1424

 Score = 42.4 bits (98), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 45/189 (23%), Positives = 81/189 (42%), Gaps = 20/189 (10%)
 Frame = +3

Query: 541  EISWK-GDGKVLALGNEDGSIEIF---QVPNLRLLCTI-QQHHKLVNAIVWHHEHGSRPE 595
            ++ W   +G V A  + D ++ I+   Q P+   + T+ + H + +N I W+      P 
Sbjct: 852  DVQWSPNEGNVFASCSVDRTLRIWNTQQKPSKANVLTVPEAHSRDINVINWN------PI 1013

Query: 596  LSCLLASGSNNAVIYVHNLKAVLESNPESPITITEPYRTLSGHTAKITSLAWSPHHDGRL 655
               LLASG ++ +I + +L+         P++    ++    H+  +TSL W+P     L
Sbjct: 1014 EKHLLASGGDDGIIKIWDLRMFRNK----PVSAQASFKL---HSQPVTSLEWNPQDSSVL 1172

Query: 656  VSACYDGTAQVWDALRE--------------EPLFNFRGHRGRLLCVAWSPVDPECIYSG 701
             ++  D    +WD   E              + LF   G +  +  V W P  P  + S 
Sbjct: 1173 AASGEDDQITIWDFSVERDEGEGEEELDVPAQLLFQHCG-QTDIKEVHWHPQLPGVLIST 1349

Query: 702  A-DDFCVYR 709
            A  DF ++R
Sbjct: 1350 AKSDFNIFR 1376

 Score = 42.4 bits (98), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 32/122 (26%), Positives = 55/122 (45%), Gaps = 5/122 (4%)
 Frame = +3

Query: 385 LAFSPVDVGSLAIGVGDGMIRVWNTLSIKNNYDVKNFWQGVKSKVTALCWHPNKEGCLAF 444
           + +SP +    A    D  +R+WNT    +  +V    +     +  + W+P ++  LA 
Sbjct: 855 VQWSPNEGNVFASCSVDRTLRIWNTQQKPSKANVLTVPEAHSRDINVINWNPIEKHLLAS 1034

Query: 445 GTDDGKVGLYD--TCSNKP--PQISSTYHKKTVYRLAWGP-PVPPMSLGGEGDRPSLTLY 499
           G DDG + ++D     NKP   Q S   H + V  L W P     ++  GE D+ ++  +
Sbjct: 1035GGDDGIIKIWDLRMFRNKPVSAQASFKLHSQPVTSLEWNPQDSSVLAASGEDDQITIWDF 1214

Query: 500 SC 501
           S 
Sbjct: 1215SV 1220

 Score = 41.2 bits (95), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 54/256 (21%), Positives = 88/256 (34%), Gaps = 27/256 (10%)
 Frame = +3

Query: 86  SDDGTVKVWDVETKTVVTE----------------HTLHQHTIS--ALHWSPTVKDLIVS 127
           SD G+V V+D+  +T + +                HT+  HT    A+ WSP  K  +V+
Sbjct: 576 SDKGSVYVYDITXQTAIVDDAEAAGKYDSTQKSIVHTVTHHTTEGFAIDWSPAAKGWLVT 755

Query: 128 GDEKGVVFCY------WLNRNDSQHLFTEPRTIFCLTCSPHHENLVAIGYKDGIVVIIDI 181
           GD  G ++        W     S    T+  ++  +  SP+  N+ A    D  + I + 
Sbjct: 756 GDCTGAIYISQPSSSGWTTEKSSYAAHTD--SVEDVQWSPNEGNVFASCSVDRTLRIWNT 929

Query: 182 SK---KGEVIHRLRGHDDEIHSIAWCPLSGEDCLSISQEENSEEPDIPNGKLIAETPITK 238
            +   K  V+     H  +I+ I W P+                                
Sbjct: 930 QQKPSKANVLTVPEAHSRDINVINWNPIEKH----------------------------- 1022

Query: 239 GCYLATGSKDQTIRIWSCSRGRGVMVLKLPFLKRRSGGVDPTVKERLWLTLHWPKNQPTQ 298
              LA+G  D  I+IW     R   V      K  S  V          +L W     + 
Sbjct: 1023--LLASGGDDGIIKIWDLRMFRNKPVSAQASFKLHSQPV---------TSLEWNPQDSSV 1169

Query: 299 LVSSCFGGELLLWDLT 314
           L +S    ++ +WD +
Sbjct: 1170LAASGEDDQITIWDFS 1217

 Score = 36.2 bits (82), Expect = 0.11,   Method: Compositional matrix adjust.
 Identities = 25/111 (22%), Positives = 53/111 (47%), Gaps = 5/111 (4%)
 Frame = +3

Query: 350 QLLLSTSMDRDVKCWDMA---TLECCWTLPSLGGFAYS-LAFSPVDVGSLAIGVGDGMIR 405
            +  S S+DR ++ W+     +     T+P       + + ++P++   LA G  DG+I+
Sbjct: 879 NVFASCSVDRTLRIWNTQQKPSKANVLTVPEAHSRDINVINWNPIEKHLLASGGDDGIIK 1058

Query: 406 VWNTLSIKNN-YDVKNFWQGVKSKVTALCWHPNKEGCLAFGTDDGKVGLYD 455
           +W+    +N     +  ++     VT+L W+P     LA   +D ++ ++D
Sbjct: 1059IWDLRMFRNKPVSAQASFKLHSQPVTSLEWNPQDSSVLAASGEDDQITIWD 1211

 Score = 32.7 bits (73), Expect = 1.00,   Method: Compositional matrix adjust.
 Identities = 17/68 (25%), Positives = 35/68 (51%), Gaps = 5/68 (7%)
 Frame = +3

Query: 75   HPGQYNLCATSSDDGTVKVWDV---ETKTVVTEHT--LHQHTISALHWSPTVKDLIVSGD 129
            +P + +L A+  DDG +K+WD+     K V  + +  LH   +++L W+P    ++ +  
Sbjct: 1005 NPIEKHLLASGGDDGIIKIWDLRMFRNKPVSAQASFKLHSQPVTSLEWNPQDSSVLAASG 1184

Query: 130  EKGVVFCY 137
            E   +  +
Sbjct: 1185 EDDQITIW 1208
>00561
          Length = 1003

 Score = 42.4 bits (98), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 39/165 (23%), Positives = 70/165 (42%), Gaps = 1/165 (0%)
 Frame = -3

Query: 540 TEISWKGDGKVLALGNEDGSIEIFQVPNLRLLCTIQQHHKLVNAIVWHHEHGSRPELSCL 599
           +++    DG     G+ D ++ ++ +   +     + H K V ++ +  ++         
Sbjct: 854 SDVVLSSDGNYALSGSWDQTLRLWDLAAGKTTRRFEGHTKDVLSVAFSADNRQ------- 696

Query: 600 LASGSNNAVIYVHNLKAVLESNPESPITITEPYRTLSGHTAKITSLAWSPHHDGRLVSAC 659
           + SGS +  I + N  A      E   TI E      GHT  ++ + +SP+H   ++ +C
Sbjct: 695 IVSGSRDKTIKLWNTLA------ECKFTIQE-----DGHTDWVSCVRFSPNHSNPIIVSC 549

Query: 660 -YDGTAQVWDALREEPLFNFRGHRGRLLCVAWSPVDPECIYSGAD 703
            +D T +VW+    +   N  GH G L  V  SP    C   G D
Sbjct: 548 GWDRTVKVWNLANCKLKNNHHGHNGYLNTVTVSPDGSLCTSGGKD 414

 Score = 41.2 bits (95), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 59/256 (23%), Positives = 102/256 (39%), Gaps = 6/256 (2%)
 Frame = -3

Query: 237 TKGCYLATGSKDQTIRIWSCSRGRGVMVLKLPFLKRRSGGVDPTVKERLWLTLHWPKNQP 296
           + G Y  +GS DQT+R+W  + G+           RR  G    V     L++ +  +  
Sbjct: 836 SDGNYALSGSWDQTLRLWDLAAGKTT---------RRFEGHTKDV-----LSVAFSADN- 702

Query: 297 TQLVSSCFGGELLLWDLTQSWRRKYTLFSTSAEGHNHSRIVFNLCSLKTEDGKQLLLSTS 356
            Q+VS      + LW+     +     F+   +GH       +           +++S  
Sbjct: 701 RQIVSGSRDKTIKLWNTLAECK-----FTIQEDGHTD---WVSCVRFSPNHSNPIIVSCG 546

Query: 357 MDRDVKCWDMATLECCWTLPSLGGFAYSLAFSPVDVGSLAIGVG-DGMIRVWNTLSIKNN 415
            DR VK W++A  +         G+  ++  SP   GSL    G D    +W+    KN 
Sbjct: 545 WDRTVKVWNLANCKLKNNHHGHNGYLNTVTVSP--DGSLCTSGGKDSKALLWDLNDGKNL 372

Query: 416 YDVKNFWQGVKSKVTALCWHPNKEG-CLAFGTDDGKVGLYDTCSNKPPQISSTY----HK 470
           Y +++        + ALC+ PN+   C+A+G     + ++D    KP +         H+
Sbjct: 371 YTLEH-----NDIINALCFSPNRYWLCVAYGP---SIKIWDLACKKPSRSCXLRSSRPHQ 216

Query: 471 KTVYRLAWGPPVPPMS 486
           +     A   P PPM+
Sbjct: 215 RPSSHSACPWPGPPMA 168

 Score = 38.5 bits (88), Expect = 0.019,   Method: Compositional matrix adjust.
 Identities = 35/122 (28%), Positives = 55/122 (45%), Gaps = 2/122 (1%)
 Frame = -3

Query: 292 PKNQPTQLVSSCFGGELLLWDLTQSWRRKYTLFSTSAEGHNH--SRIVFNLCSLKTEDGK 349
           PK+ P  ++S+     L++W LT+     Y        GH+H  S +V       + DG 
Sbjct: 983 PKD-PDTIISASRDKTLIVWKLTRDEDTNYGYPQKRLYGHSHFISDVVL------SSDG- 828

Query: 350 QLLLSTSMDRDVKCWDMATLECCWTLPSLGGFAYSLAFSPVDVGSLAIGVGDGMIRVWNT 409
              LS S D+ ++ WD+A  +             S+AFS  D   +  G  D  I++WNT
Sbjct: 827 NYALSGSWDQTLRLWDLAAGKTTRRFEGHTKDVLSVAFS-ADNRQIVSGSRDKTIKLWNT 651

Query: 410 LS 411
           L+
Sbjct: 650 LA 645

 Score = 31.2 bits (69), Expect = 3.4,   Method: Compositional matrix adjust.
 Identities = 33/120 (27%), Positives = 53/120 (44%), Gaps = 4/120 (3%)
 Frame = -3

Query: 62  GHTERVSGFTFSHHPGQYN-LCATSSDDGTVKVWDVETKTVVTEHTLHQHTISALHWSPT 120
           GHT+ VS   FS  P   N +  +   D TVKVW++    +   H  H   ++ +  SP 
Sbjct: 617 GHTDWVSCVRFS--PNHSNPIIVSCGWDRTVKVWNLANCKLKNNHHGHNGYLNTVTVSPD 444

Query: 121 VKDLIVSG--DEKGVVFCYWLNRNDSQHLFT-EPRTIFCLTCSPHHENLVAIGYKDGIVV 177
              L  SG  D K +++    + ND ++L+T E   I    C   +   + + Y   I +
Sbjct: 443 -GSLCTSGGKDSKALLW----DLNDGKNLYTLEHNDIINALCFSPNRYWLCVAYGPSIKI 279
>12841
          Length = 1364

 Score = 39.7 bits (91), Expect = 0.009,   Method: Compositional matrix adjust.
 Identities = 22/72 (30%), Positives = 32/72 (44%), Gaps = 3/72 (4%)
 Frame = +1

Query: 634  TLSGHTAKITSLAWSPHHDGRLVSACYDGTAQVWDALREEPLFNFRGHRGRLLCVAWSPV 693
            T SGHTA +  + WSP      +S   D + ++W   R  P+  F      +  V WSP 
Sbjct: 1033 TYSGHTAPVYHIRWSPFVSDIFLSCSADWSIRLWHQDRTTPILTFHSSTKTVHDVCWSPR 1212

Query: 694  DPE---CIYSGA 702
                  C++ GA
Sbjct: 1213 SSTVFACVHEGA 1248

 Score = 32.7 bits (73), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 46/198 (23%), Positives = 79/198 (39%), Gaps = 23/198 (11%)
 Frame = +1

Query: 546 GDGKVLALGNEDGSIEIFQV------PNLRLLCTIQQHHKLVNAIVW-HHEHGSRPELSC 598
            +  +LA G  DG + I+ V      P L    T  +H   V  I W   E GS  E + 
Sbjct: 586 ANANILAAGYYDGGVAIYNVRSTSDEPILDNQETHGKHLGPVWQIQWIEKERGSGEERAE 765

Query: 599 LLASGSNNAVIYVHNLKAVLESNPESPITITEPYRTLSGHTAKITSLAWSPHHDGRLVSA 658
           +L S S +  +   +++   ESN  + + + +    ++G   +    A+   H G L   
Sbjct: 766 VLISISTDGRVTQWSIRKGFESN--NIMRLKKLPTRMAGKAREKKGEAFISRHAGGL--- 930

Query: 659 CYD-----------GTAQVWD-----ALREEPLFNFRGHRGRLLCVAWSPVDPECIYSGA 702
           C+D           GT + +      +  E+ L  + GH   +  + WSP   +   S +
Sbjct: 931 CFDFHSRDLNVYLAGTEEGYIHKCSCSYNEQYLETYSGHTAPVYHIRWSPFVSDIFLSCS 1110

Query: 703 DDFCVYRWLTSMQDHSRP 720
            D+ +  W    QD + P
Sbjct: 1111ADWSIRLW---HQDRTTP 1155
>27465
          Length = 658

 Score = 39.7 bits (91), Expect = 0.009,   Method: Compositional matrix adjust.
 Identities = 19/81 (23%), Positives = 39/81 (48%)
 Frame = -1

Query: 630 EPYRTLSGHTAKITSLAWSPHHDGRLVSACYDGTAQVWDALREEPLFNFRGHRGRLLCVA 689
           E   TL GH   + ++A++     ++++  +D T ++W     +     RGH   ++CV+
Sbjct: 262 EELHTLEGHRNVVYAIAFNNPFGDKVITGSFDKTCKLWSTADGKCYHTLRGHTAEIVCVS 83

Query: 690 WSPVDPECIYSGADDFCVYRW 710
           ++P     I +G+ D     W
Sbjct: 82  FNP-SSTLIATGSMDTTCRLW 23

 Score = 38.5 bits (88), Expect = 0.023,   Method: Compositional matrix adjust.
 Identities = 19/82 (23%), Positives = 39/82 (47%)
 Frame = -1

Query: 632 YRTLSGHTAKITSLAWSPHHDGRLVSACYDGTAQVWDALREEPLFNFRGHRGRLLCVAWS 691
           ++ L  H   +T++A++       ++  YD T ++WD    E L    GHR  +  +A++
Sbjct: 382 FKVLRAHILPLTNVAFNKS-GSSFITGSYDRTCKIWDTASAEELHTLEGHRNVVYAIAFN 206

Query: 692 PVDPECIYSGADDFCVYRWLTS 713
               + + +G+ D     W T+
Sbjct: 205 NPFGDKVITGSFDKTCKLWSTA 140
>12806
          Length = 961

 Score = 37.7 bits (86), Expect = 0.032,   Method: Composition-based stats.
 Identities = 23/76 (30%), Positives = 39/76 (51%)
 Frame = +3

Query: 62  GHTERVSGFTFSHHPGQYNLCATSSDDGTVKVWDVETKTVVTEHTLHQHTISALHWSPTV 121
            HT+ V+   F H   +  +  ++S+D T+KVWD  T T+      H+  I+AL  S   
Sbjct: 414 AHTDWVTCVRF-HQDTKNPIVVSASNDKTIKVWDNHTMTLKNTFVGHKAQITALDMS--- 581

Query: 122 KDLIVSGDEKGVVFCY 137
            + +VSG + G+   +
Sbjct: 582 TNYLVSGSKDGIAMTW 629
>30256
          Length = 961

 Score = 37.7 bits (86), Expect = 0.040,   Method: Composition-based stats.
 Identities = 63/255 (24%), Positives = 94/255 (36%), Gaps = 38/255 (14%)
 Frame = +3

Query: 239 GCYLATGSKDQTIRIWSCSRGRGVMVLKLPFLKRRSGGVDPTVKERLWLTLHWPKNQPTQ 298
           G  + +GS D+++++W+   G     L          G   TV+    L+L   K     
Sbjct: 72  GNTVISGSTDRSLKVWNADTGVCTHTLY---------GHSSTVR---CLSLSGKK----- 200

Query: 299 LVSSCFGGELLLWDLTQSWRRKYTLFSTSAEGHNHSRIVFNLCSLK--TEDGKQLLLSTS 356
           +VS      L +WD+                GH  + ++ ++ +++    DGK+++ S +
Sbjct: 201 VVSGSRDATLRVWDIES--------------GHCLNVLLGHMAAVRCVQYDGKRVV-SGA 335

Query: 357 MDRDVKCWDMATLECCWTLPSLGGFAYSLAFSPVDVGSLAIGVGDGMIRVWNT------- 409
            D  V+ WD  T  C  TL       YSL F  V V S   G  D  IRVW+        
Sbjct: 336 XDYTVRVWDPDTASCLHTLQGHTNRVYSLQFDGVYVVS---GSLDTSIRVWDVRCGKLVH 506

Query: 410 -----------LSIKNNYDVK-------NFWQGVKSKVTALCWHPNKE----GCLAFG-- 445
                      L +K+N  V          W     K       PNK      CL F   
Sbjct: 507 TLMGHQSLTSGLELKDNLLVSGNADSTVKVWDVHTGKCLQTLLGPNKHRSAVTCLQFNKK 686

Query: 446 -----TDDGKVGLYD 455
                +DDG V L+D
Sbjct: 687 FVVTCSDDGTVKLWD 731

 Score = 37.0 bits (84), Expect = 0.059,   Method: Composition-based stats.
 Identities = 36/131 (27%), Positives = 62/131 (47%), Gaps = 11/131 (8%)
 Frame = +3

Query: 55  RVVGELVGHTERVSGFTFSHHPGQYNLCATSSDDGTVKVWDVETKTVVTEHTL-----HQ 109
           ++V  L+GH    SG          NL  + + D TVKVWDV T   +   TL     H+
Sbjct: 495 KLVHTLMGHQSLTSGLELKD-----NLLVSGNADSTVKVWDVHTGKCL--QTLLGPNKHR 653

Query: 110 HTISALHWSPTVKDLIVSGDEKGVVFCYWLNRND-SQHLFTEPR-----TIFCLTCSPHH 163
             ++ L ++   K  +V+  + G V  + LN  D  ++L T P       ++ L C+ + 
Sbjct: 654 SAVTCLQFN---KKFVVTCSDDGTVKLWDLNTGDFIRNLITLPSGGSGGVVWRLRCN-NT 821

Query: 164 ENLVAIGYKDG 174
           + + A+G ++G
Sbjct: 822 KMVCAVGSRNG 854

 Score = 31.2 bits (69), Expect = 2.9,   Method: Composition-based stats.
 Identities = 32/131 (24%), Positives = 53/131 (40%), Gaps = 7/131 (5%)
 Frame = +3

Query: 587 HHEHGSRPELSCL------LASGSNNAVIYVHNLKAVLESNPESPITITEPYRTLSGHTA 640
           H  +G    + CL      + SGS +A + V ++++                  L GH A
Sbjct: 144 HTLYGHSSTVRCLSLSGKKVVSGSRDATLRVWDIES------------GHCLNVLLGHMA 287

Query: 641 KITSLAWSPHHDG-RLVSACYDGTAQVWDALREEPLFNFRGHRGRLLCVAWSPVDPECIY 699
            +  +     +DG R+VS   D T +VWD      L   +GH  R+  + +  V    + 
Sbjct: 288 AVRCV----QYDGKRVVSGAXDYTVRVWDPDTASCLHTLQGHTNRVYSLQFDGV---YVV 446

Query: 700 SGADDFCVYRW 710
           SG+ D  +  W
Sbjct: 447 SGSLDTSIRVW 479

 Score = 31.2 bits (69), Expect = 3.5,   Method: Composition-based stats.
 Identities = 49/223 (21%), Positives = 83/223 (37%), Gaps = 23/223 (10%)
 Frame = +3

Query: 60  LVGHTERVSGFTFSHHPGQYNLCATSSDDGTVKVWDVETKTVVTEHTLHQHTISALHWSP 119
           L GH+  V   + S          + S D T++VWD+E+   +     H   +  + +  
Sbjct: 150 LYGHSSTVRCLSLSGKK-----VVSGSRDATLRVWDIESGHCLNVLLGHMAAVRCVQYD- 311

Query: 120 TVKDLIVSGDEKGVVFCYWLNRNDSQHLFTEPRTIFCLTCSPHHENLVAIGYKDGIVVI- 178
                +VSG     V  +            +P T  CL     H N V     DG+ V+ 
Sbjct: 312 --GKRVVSGAXDYTVRVW------------DPDTASCLHTLQGHTNRVYSLQFDGVYVVS 449

Query: 179 --IDISKK------GEVIHRLRGHDDEIHSIAWCPLSGEDCLSISQEENSEEP--DIPNG 228
             +D S +      G+++H L GH           L  +D L +S   +S     D+  G
Sbjct: 450 GSLDTSIRVWDVRCGKLVHTLMGHQSLTSG-----LELKDNLLVSGNADSTVKVWDVHTG 614

Query: 229 KLIA--------ETPIT----KGCYLATGSKDQTIRIWSCSRG 259
           K +          + +T       ++ T S D T+++W  + G
Sbjct: 615 KCLQTLLGPNKHRSAVTCLQFNKKFVVTCSDDGTVKLWDLNTG 743
>12574
          Length = 521

 Score = 37.4 bits (85), Expect = 0.042,   Method: Composition-based stats.
 Identities = 25/77 (32%), Positives = 41/77 (53%)
 Frame = +3

Query: 634 TLSGHTAKITSLAWSPHHDGRLVSACYDGTAQVWDALREEPLFNFRGHRGRLLCVAWSPV 693
           TL+GHT  ++++ +SP+ D  L S+  D   ++W A   +      GH+  L  VAWS  
Sbjct: 171 TLAGHTKALSAVKFSPNGDW-LASSSADKLIKIWGAYDGKFEKTIAGHKLGLSDVAWSS- 344

Query: 694 DPECIYSGADDFCVYRW 710
           D + + S +DD  +  W
Sbjct: 345 DSKLLCSASDDKTLKIW 395

 Score = 33.9 bits (76), Expect = 0.45,   Method: Composition-based stats.
 Identities = 17/61 (27%), Positives = 34/61 (55%), Gaps = 1/61 (1%)
 Frame = +3

Query: 633 RTLSGHTAKITSLAWSPHHDGRLV-SACYDGTAQVWDALREEPLFNFRGHRGRLLCVAWS 691
           +T++GH   ++ +AWS   D +L+ SA  D T ++W+    + +   +GH   + C  ++
Sbjct: 294 KTIAGHKLGLSDVAWSS--DSKLLCSASDDKTLKIWEFSTGKCMKTLKGHSNYVFCCNFN 467

Query: 692 P 692
           P
Sbjct: 468 P 470

 Score = 29.6 bits (65), Expect = 9.0,   Method: Composition-based stats.
 Identities = 17/66 (25%), Positives = 28/66 (42%)
 Frame = +3

Query: 324 FSTSAEGHNHSRIVFNLCSLKTEDGKQLLLSTSMDRDVKCWDMATLECCWTLPSLGGFAY 383
           F  +  GH        L  +      +LL S S D+ +K W+ +T +C  TL     + +
Sbjct: 288 FEKTIAGHK-----LGLSDVAWSSDSKLLCSASDDKTLKIWEFSTGKCMKTLKGHSNYVF 452

Query: 384 SLAFSP 389
              F+P
Sbjct: 453 CCNFNP 470
>13278
          Length = 870

 Score = 37.0 bits (84), Expect = 0.061,   Method: Compositional matrix adjust.
 Identities = 30/109 (27%), Positives = 50/109 (45%)
 Frame = +1

Query: 75  HPGQYNLCATSSDDGTVKVWDVETKTVVTEHTLHQHTISALHWSPTVKDLIVSGDEKGVV 134
           +P    + A++S D TV++W+VE    +   T HQ  + ++ +SP  K L  SG     V
Sbjct: 100 NPNTSLILASASFDSTVRLWEVERGLCLHTLTKHQEPVYSVAFSPDGKYL-ASGSFDKCV 276

Query: 135 FCYWLNRNDSQHLFTEPRTIFCLTCSPHHENLVAIGYKDGIVVIIDISK 183
             + +      H +     IF + C  H  + V     DG V ++D+ K
Sbjct: 277 HIWNVQTGSLVHSYKGTGGIFEV-CWNHRGDKVGASASDGSVFVLDLRK 420

 Score = 33.9 bits (76), Expect = 0.53,   Method: Compositional matrix adjust.
 Identities = 22/58 (37%), Positives = 29/58 (50%)
 Frame = +1

Query: 351 LLLSTSMDRDVKCWDMATLECCWTLPSLGGFAYSLAFSPVDVGSLAIGVGDGMIRVWN 408
           +L S S D  V+ W++    C  TL       YS+AFSP D   LA G  D  + +WN
Sbjct: 118 ILASASFDSTVRLWEVERGLCLHTLTKHQEPVYSVAFSP-DGKYLASGSFDKCVHIWN 288
>03395
          Length = 2795

 Score = 36.6 bits (83), Expect = 0.089,   Method: Composition-based stats.
 Identities = 25/74 (33%), Positives = 37/74 (50%), Gaps = 4/74 (5%)
 Frame = +2

Query: 395 LAIGVGDGMIRVWN----TLSIKNNYDVKNFWQGVKSKVTALCWHPNKEGCLAFGTDDGK 450
           L  G G+G +RVW+     L+ K   D+    +  K KVTA+  H N   C++  T DG 
Sbjct: 41  LVSGGGEGQVRVWDIVKDMLTGKTRGDLVANMKEHKGKVTAIQIHTNDRCCVSAST-DGS 217

Query: 451 VGLYDTCSNKPPQI 464
             ++D  +N   QI
Sbjct: 218 TIIWDLITNTRSQI 259
>15337
          Length = 860

 Score = 36.2 bits (82), Expect = 0.11,   Method: Compositional matrix adjust.
 Identities = 27/79 (34%), Positives = 39/79 (49%)
 Frame = -1

Query: 632 YRTLSGHTAKITSLAWSPHHDGRLVSACYDGTAQVWDALREEPLFNFRGHRGRLLCVAWS 691
           YR + G T  I+  A+SP     L     DG  +V++    E +   + + G LLCV WS
Sbjct: 347 YRWVVG-TGAISEFAFSPCSR-YLAVVGQDGHLRVFNYNSMELIGTMKSYFGGLLCVCWS 174

Query: 692 PVDPECIYSGADDFCVYRW 710
           P D + I +G +D  V  W
Sbjct: 173 P-DGKYIVTGGEDDLVTVW 120

 Score = 30.8 bits (68), Expect = 4.0,   Method: Compositional matrix adjust.
 Identities = 12/45 (26%), Positives = 21/45 (46%)
 Frame = -1

Query: 542 ISWKGDGKVLALGNEDGSIEIFQVPNLRLLCTIQQHHKLVNAIVW 586
           + W  DGK +  G ED  + ++     R++C    H   VN + +
Sbjct: 185 VCWSPDGKYIVTGGEDDLVTVWSFHEKRVVCRGHGHKSWVNVVAF 51
>20662
          Length = 1220

 Score = 35.8 bits (81), Expect = 0.13,   Method: Compositional matrix adjust.
 Identities = 34/168 (20%), Positives = 69/168 (41%), Gaps = 10/168 (5%)
 Frame = +2

Query: 54  FRVVGELVGHTERVSGFTFSHHPGQYNLCATSSDDGTVKVWDVETKTVVTEHTLHQHTIS 113
           F ++     H +  +  + +     Y    ++S D  +KVW+ +  ++ T +  H   + 
Sbjct: 356 FSMLSSACEHDDMTASVSINSDXSHY---LSASYDHGIKVWNTDLTSLYT-YRAHSDIVW 523

Query: 114 ALHWSPTVKDLIVSGDEKGVVFCYWLNRNDSQHLFTEPRTIFCLTC---SPHHENLVAIG 170
            +   PT   L +S  + G +  + +  +       +  + F  TC    P+  N+ A+G
Sbjct: 524 DVQCHPTEPALFLSCSQDGKIVLWDVRESKPATCLPKCSSGFKPTCVQWQPNARNMYAVG 703

Query: 171 YKDGIVVIIDISKKGEVIHRLRGHDDEIHSIAWCPLS-------GEDC 211
            + G V + D+    E     + H+  +  +A+CP         GEDC
Sbjct: 704 DEGGHVSVQDLRMVVEKNVSYQSHNRVVTRLAFCPQRPSMLASIGEDC 847
>30295
          Length = 593

 Score = 35.8 bits (81), Expect = 0.15,   Method: Composition-based stats.
 Identities = 26/88 (29%), Positives = 38/88 (43%), Gaps = 1/88 (1%)
 Frame = +2

Query: 633 RTLSGHTAKITSLAWSPHHDGR-LVSACYDGTAQVWDALREEPLFNFRGHRGRLLCVAWS 691
           RTL  H AKI ++ W+   D R LVSA  DG   VWD      +         ++  A++
Sbjct: 227 RTLRXHLAKIYAMHWAT--DSRNLVSASQDGKLIVWDGYTTNKVHAIPLRSSWVMTCAYA 400

Query: 692 PVDPECIYSGADDFCVYRWLTSMQDHSR 719
           P        G D+ C    L + + + R
Sbjct: 401 PSGGYVACGGLDNICSIYSLKTREGNVR 484
>26107
          Length = 1338

 Score = 35.0 bits (79), Expect = 0.25,   Method: Compositional matrix adjust.
 Identities = 19/54 (35%), Positives = 28/54 (51%)
 Frame = -3

Query: 82   CATSSDDGTVKVWDVETKTVVTEHTLHQHTISALHWSPTVKDLIVSGDEKGVVF 135
            C T+S D TV +WDVET T VT    H+ ++ ++   P+      SG   G + 
Sbjct: 1042 CLTASGDQTVALWDVETTTKVTTFIGHKCSVRSVASCPSSPAQCASGARDGHIM 881

 Score = 32.0 bits (71), Expect = 2.0,   Method: Compositional matrix adjust.
 Identities = 20/74 (27%), Positives = 31/74 (41%)
 Frame = -3

Query: 637  GHTAKITSLAWSPHHDGRLVSACYDGTAQVWDALREEPLFNFRGHRGRLLCVAWSPVDPE 696
             H   +   +W  + D + ++A  D T  +WD      +  F GH+  +  VA  P  P 
Sbjct: 1093 AHNNAVFDYSWISN-DSQCLTASGDQTVALWDVETTTKVTTFIGHKCSVRSVASCPSSPA 917

Query: 697  CIYSGADDFCVYRW 710
               SGA D  +  W
Sbjct: 916  QCASGARDGHIMLW 875
>17266
          Length = 480

 Score = 34.7 bits (78), Expect = 0.27,   Method: Composition-based stats.
 Identities = 37/149 (24%), Positives = 61/149 (40%), Gaps = 1/149 (0%)
 Frame = -1

Query: 542 ISWKGDGKVLALGNEDGSIEIFQVPNLRLLCTIQQHHKLVNAIVWHHEHGSRPELSCLLA 601
           +S   D +    G  D S +++ V +     T   H   +NAI +     +        A
Sbjct: 441 LSLAPDMRTFVSGACDASAKLWDVRDGMCKQTFSGHESDINAITYFPNGHA-------FA 283

Query: 602 SGSNNAVIYVHNLKAVLESNPESPITITEPYRTLSGHTAKITSLAWSPHHDGRLVSACYD 661
           +GS++A   + +++A  E    S   I             ITS+A+S    GRL+   YD
Sbjct: 282 TGSDDATCRLFDIRADQEIGMYSHDNII----------CGITSVAFS--KSGRLLLGGYD 139

Query: 662 G-TAQVWDALREEPLFNFRGHRGRLLCVA 689
                +WD L++E      GH  R+ C+ 
Sbjct: 138 DFNCNIWDVLKQERTGVLAGHDNRVSCLG 52
>02147
          Length = 1547

 Score = 34.7 bits (78), Expect = 0.27,   Method: Compositional matrix adjust.
 Identities = 48/201 (23%), Positives = 76/201 (37%)
 Frame = +2

Query: 60  LVGHTERVSGFTFSHHPGQYNLCATSSDDGTVKVWDVETKTVVTEHTLHQHTISALHWSP 119
             GHT  + G  F     +     ++SDD TV++W +ET   V + T      S L  SP
Sbjct: 413 FAGHTSNIKGALFLSDGKR---IISASDDKTVRLWSLETCQEVQQLTFDTPPTS-LTLSP 580

Query: 120 TVKDLIVSGDEKGVVFCYWLNRNDSQHLFTEPRTIFCLTCSPHHENLVAIGYKDGIVVII 179
               +IV+  +    +     R   +     P +   L  S   E     G +D  +   
Sbjct: 581 DKNTIIVTHSQNIAFYQADTLREMKKFEAEAPISSASLHQS---ERFFVAGGEDFKMYKF 751

Query: 180 DISKKGEVIHRLRGHDDEIHSIAWCPLSGEDCLSISQEENSEEPDIPNGKLIAETPITKG 239
           D  + G+ I   +GH   +H           C+  S          P+G+L         
Sbjct: 752 DY-ETGKEIESFKGHFGPVH-----------CVRFS----------PDGEL--------- 838

Query: 240 CYLATGSKDQTIRIWSCSRGR 260
              A+GS+D T+R+W  + GR
Sbjct: 839 --YASGSEDGTLRLWQTTIGR 895
>02090
          Length = 1841

 Score = 34.7 bits (78), Expect = 0.28,   Method: Compositional matrix adjust.
 Identities = 24/68 (35%), Positives = 34/68 (50%), Gaps = 1/68 (1%)
 Frame = -3

Query: 644  SLAWSPHHDGRL-VSACYDGTAQVWDALREEPLFNFRGHRGRLLCVAWSPVDPECIYSGA 702
            +LA SP  DG++  S C DG   VWD   +  +  F+GH     C+  SP D   +++G 
Sbjct: 1611 ALAISP--DGKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISP-DGTKLWTGG 1441

Query: 703  DDFCVYRW 710
             D  V  W
Sbjct: 1440 LDNTVRSW 1417
>04395
          Length = 1145

 Score = 33.9 bits (76), Expect = 0.47,   Method: Compositional matrix adjust.
 Identities = 13/22 (59%), Positives = 17/22 (77%)
 Frame = +3

Query: 75  HPGQYNLCATSSDDGTVKVWDV 96
           HPGQ ++ AT S DGT+ VWD+
Sbjct: 501 HPGQLHIVATGSQDGTLTVWDL 566
>19140
          Length = 573

 Score = 33.9 bits (76), Expect = 0.50,   Method: Compositional matrix adjust.
 Identities = 23/103 (22%), Positives = 43/103 (41%)
 Frame = -3

Query: 59  ELVGHTERVSGFTFSHHPGQYNLCATSSDDGTVKVWDVETKTVVTEHTLHQHTISALHWS 118
           +L GHT+ V     +    Q   C + S DGT+++W +  +  V    +H   + AL  +
Sbjct: 502 KLKGHTDNVKALVLNRDGTQ---CLSGSSDGTIRLWSLGQQRCVATFRVHDEGVWALQAN 332

Query: 119 PTVKDLIVSGDEKGVVFCYWLNRNDSQHLFTEPRTIFCLTCSP 161
            +   L   G +  V      N ++ + +  E   +  L  +P
Sbjct: 331 ESFTTLYSGGRDHQVWATDIKNPDNRELICEEKAPVLKLELTP 203
>17602
          Length = 481

 Score = 33.5 bits (75), Expect = 0.59,   Method: Compositional matrix adjust.
 Identities = 18/58 (31%), Positives = 31/58 (53%), Gaps = 2/58 (3%)
 Frame = +3

Query: 655 LVSACYDGTAQVWDALREEPLFNFRGHRGRLLCV--AWSPVDPECIYSGADDFCVYRW 710
           +++A  D T ++WD  + + L  + GHR    C+   +S    + I SG++D  VY W
Sbjct: 228 ILAATLDNTLKLWDYSKGKCLKTYVGHRNEKYCIFANFSVTGGKWIVSGSEDNMVYIW 401
>01557
          Length = 953

 Score = 33.5 bits (75), Expect = 0.72,   Method: Compositional matrix adjust.
 Identities = 26/114 (22%), Positives = 45/114 (39%), Gaps = 20/114 (17%)
 Frame = +2

Query: 598 CLLASGSNNAVIYVHNLKAVLESNPESPIT----------------ITEPYRTLSGHTAK 641
           CL   G ++A     N   V +S P+  ++                +   YR  + HT K
Sbjct: 188 CLFLVGDDSAHKAPINQLCVFKSRPQQAVSTCLDNTLNVWDLSGADLCSVYRARAAHTNK 367

Query: 642 ITSLAWSPHHDGRLVSACYDGTAQVWDALREEP----LFNFRGHRGRLLCVAWS 691
           +T LA S     +L++    G A++WD     P    L++ + +     C  W+
Sbjct: 368 LTGLALSATTAAQLITCDRGGCARLWDLRSSSPSSCCLYDNKTNLLSFSCATWA 529
>20271
          Length = 567

 Score = 32.7 bits (73), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 23/83 (27%), Positives = 37/83 (44%), Gaps = 3/83 (3%)
 Frame = -1

Query: 62  GHTERVSGFTFSHHPGQYNLC---ATSSDDGTVKVWDVETKTVVTEHTLHQHTISALHWS 118
           GH   ++     H  GQ +      T+S D TVK+W+++ +  V     +   +S + WS
Sbjct: 291 GHQGPITAIDTHHAAGQIDFSPFFLTASFDWTVKLWNIKEQKYVCSFEDNSDYVSDVQWS 112

Query: 119 PTVKDLIVSGDEKGVVFCYWLNR 141
           PT   L    D  G +  + LN 
Sbjct: 111 PTNPALFSCVDIMGRLDLWHLNH 43

 Score = 32.0 bits (71), Expect = 2.0,   Method: Compositional matrix adjust.
 Identities = 24/103 (23%), Positives = 46/103 (44%), Gaps = 6/103 (5%)
 Frame = -1

Query: 599 LLASGSNNAVIYVHNLKAVLESNPESPITITEPYRTLSGHTAKITSLAWSPHHDGRL--- 655
            L+  +NN ++          S   S   I E Y    GH   IT++  + H  G++   
Sbjct: 396 FLSGDANNFIVGSEECLVYSASRHGSKAGINEAYE---GHQGPITAID-THHAAGQIDFS 229

Query: 656 ---VSACYDGTAQVWDALREEPLFNFRGHRGRLLCVAWSPVDP 695
              ++A +D T ++W+   ++ + +F  +   +  V WSP +P
Sbjct: 228 PFFLTASFDWTVKLWNIKEQKYVCSFEDNSDYVSDVQWSPTNP 100
>15056
          Length = 445

 Score = 32.3 bits (72), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 20/69 (28%), Positives = 32/69 (46%), Gaps = 18/69 (26%)
 Frame = -2

Query: 86  SDDGTVKVWDVETKTVVTE----------------HTLHQHTIS--ALHWSPTVKDLIVS 127
           SD G+V V+D+  +T + +                HT+  HT    A+ WSP  K  +V+
Sbjct: 282 SDKGSVYVYDITXQTXIVDDAEAAGKYDSTQKSIVHTVTHHTTEGFAIDWSPAAKGWLVT 103

Query: 128 GDEKGVVFC 136
           GD  G ++ 
Sbjct: 102 GDCTGAIYI 76
>17598
          Length = 875

 Score = 32.3 bits (72), Expect = 1.4,   Method: Composition-based stats.
 Identities = 51/214 (23%), Positives = 84/214 (39%), Gaps = 5/214 (2%)
 Frame = +1

Query: 241 YLATGSKDQTIRIWSCSRGRGVMVLKLPFLKRRSGGVDPTVKERLWLTLHWPKNQPTQLV 300
           Y+ + S D T+R+W   +G            RR        ++ L +    P N+  Q+ 
Sbjct: 163 YVLSSSWDATLRLWDIKKGNTT---------RR---FISHTRDALAVAFS-PDNR--QIA 297

Query: 301 SSCFGGELLLWDLTQSWRRKYTLFSTSAEGHNHSRIVFNLCSLKTEDGKQ-LLLSTSMDR 359
           S      L +W+     +     F+  A  H      +  C    +D K  L++S SMD+
Sbjct: 298 SGGRDKALKIWNTVGECK-----FTVDANSHQD----WVTCVKFHQDAKSPLVVSASMDK 450

Query: 360 DVKCWDMATLECCWTLPSLGGFAYSLAFSPVDVG----SLAIGVGDGMIRVWNTLSIKNN 415
            +K WD  T+    T        +    + +D+      LA G  DG++  WN   I+N 
Sbjct: 451 TIKVWDNQTMTLKHTF-----VGHKTQINAIDLALKTYYLASGSKDGIVMTWN---IQNG 606

Query: 416 YDVKNFWQGVKSKVTALCWHPNKEGCLAFGTDDG 449
             +         +V A+ + PNK   L  GT +G
Sbjct: 607 TFLGKI--DCDCEVNAVKFSPNKY-WLFVGTSEG 699

 Score = 32.0 bits (71), Expect = 2.0,   Method: Composition-based stats.
 Identities = 22/75 (29%), Positives = 37/75 (49%)
 Frame = +1

Query: 63  HTERVSGFTFSHHPGQYNLCATSSDDGTVKVWDVETKTVVTEHTLHQHTISALHWSPTVK 122
           H + V+   F H   +  L  ++S D T+KVWD +T T+      H+  I+A+  +    
Sbjct: 373 HQDWVTCVKF-HQDAKSPLVVSASMDKTIKVWDNQTMTLKHTFVGHKTQINAIDLALKTY 549

Query: 123 DLIVSGDEKGVVFCY 137
            L  SG + G+V  +
Sbjct: 550 YL-ASGSKDGIVMTW 591
>14500
          Length = 1238

 Score = 32.3 bits (72), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 37/130 (28%), Positives = 54/130 (41%), Gaps = 6/130 (4%)
 Frame = +3

Query: 599 LLASGSNNAVIYVHNLKAVLESNPESPITITEPYRTLSGHTAKITSLAWSPHHDGRLVSA 658
           LLASG   A  ++H       +N  S  T            +++ +L WS  H   L+S+
Sbjct: 246 LLASGGGTADRHIHFWNCNTGTNLSSVDT-----------KSQVCALLWSKEHR-ELISS 389

Query: 659 CYDGTAQ----VWDALREEPLFNFRGHRGRLLCVAWSPVDPECIYSGADDFCVYRW--LT 712
              G AQ    +W       +    GH  R+L +A SP D E + S A D  +  W   T
Sbjct: 390 --HGFAQNQLIIWKYPAMSRVAELTGHTARVLHMAMSP-DGETVVSAAADETLRLWKCFT 560

Query: 713 SMQDHSRPPQ 722
             ++  RP Q
Sbjct: 561 VDKEKKRPKQ 590

 Score = 30.4 bits (67), Expect = 5.2,   Method: Compositional matrix adjust.
 Identities = 22/62 (35%), Positives = 30/62 (48%), Gaps = 6/62 (9%)
 Frame = +2

Query: 634 TLSGHTAKITSLAWSPHHDGR-LVSACYDGTAQVWDAL-----REEPLFNFRGHRGRLLC 687
           TLSGH+ ++  L WSP  DG+ L S   D    VW A        +PL  F  H+  +  
Sbjct: 44  TLSGHSQEVCGLRWSP--DGKYLASGANDNLLCVWPAQVTGGNSTQPLHTFSQHQAAVKA 217

Query: 688 VA 689
           +A
Sbjct: 218 LA 223
>31474
          Length = 403

 Score = 32.0 bits (71), Expect = 1.8,   Method: Compositional matrix adjust.
 Identities = 32/131 (24%), Positives = 51/131 (38%), Gaps = 2/131 (1%)
 Frame = -3

Query: 563 FQVPNLRLLCTIQQHHKLVNAIVWHHEHGSRPELSCLLASGSNNAVIYVHNLKAVLESNP 622
             +  L  +C +  H +    + W+           LLAS  ++ +I +   +     N 
Sbjct: 350 MAMATLEEVCCLSAHDEHAWCVAWN-------PTGTLLASCGSDKIIKIWGKEG---DNW 201

Query: 623 ESPITITEPYRTLSGHTAKITSLAWSPHHDGRLVSACYDGTAQVWD--ALREEPLFNFRG 680
               T+T+       HT  + SL WSP  +  L SA +D T  VW       E +    G
Sbjct: 200 VCKSTLTDA------HTRTVRSLGWSPCGN-YLSSASFDATTAVWSRKGGEFECIATLEG 42

Query: 681 HRGRLLCVAWS 691
           H   +  VAW+
Sbjct: 41  HENEVKAVAWA 9
>31054
          Length = 392

 Score = 31.6 bits (70), Expect = 2.4,   Method: Compositional matrix adjust.
 Identities = 17/36 (47%), Positives = 22/36 (61%)
 Frame = -2

Query: 633 RTLSGHTAKITSLAWSPHHDGRLVSACYDGTAQVWD 668
           + LSGH A I +LA   + DG LVS   +GT  +WD
Sbjct: 307 QNLSGHNAIINTLA--VNSDGVLVSGADNGTMHLWD 206
>07741
          Length = 2119

 Score = 31.6 bits (70), Expect = 2.5,   Method: Compositional matrix adjust.
 Identities = 22/88 (25%), Positives = 36/88 (40%), Gaps = 13/88 (14%)
 Frame = +1

Query: 634 TLSGHTAKITSLAWSPHHDGRLVSACYDGTAQVW-----------DALREEPLFNFRGHR 682
           TL  H   +  +AW+ +H     +   D   ++W           D+L  +PLF+F  + 
Sbjct: 226 TLDSHNMAVYKVAWNHYHPKIYATCSADWNVKIWENGGKPTDTGXDSLSRKPLFSFDLNN 405

Query: 683 GRLLCVAWSPVDPECIYSGADD--FCVY 708
             +  VAW+P       +   D   CVY
Sbjct: 406 S-VGDVAWAPYSSTVFAAVTADGKVCVY 486
>25880
          Length = 423

 Score = 31.2 bits (69), Expect = 3.4,   Method: Compositional matrix adjust.
 Identities = 24/81 (29%), Positives = 39/81 (48%), Gaps = 5/81 (6%)
 Frame = +2

Query: 185 GEVIHRLRGHDDEIHSIAWCPLSGEDCLSISQEE-----NSEEPDIPNGKLIAETPITKG 239
           G  IH  + H   + S+A+   S E+ ++ S E+     N E+PD         T   K 
Sbjct: 29  GAEIHSFQ-HKHIVKSVAFDN-SSENIVTGSNEKLVRVFNLEQPDAEPELYGGHTGAIKR 202

Query: 240 CYLATGSKDQTIRIWSCSRGR 260
              A+GS+D T+R+W  + G+
Sbjct: 203 ALYASGSEDGTLRLWQTTVGK 265
>06614
          Length = 936

 Score = 31.2 bits (69), Expect = 3.7,   Method: Compositional matrix adjust.
 Identities = 21/43 (48%), Positives = 23/43 (53%), Gaps = 4/43 (9%)
 Frame = -2

Query: 880 EDVSADLEERFHL----GLFTDRATLYRMMETEGKGHLESGHP 918
           ED    LEE  HL     L TD     R+   EG+GHLESGHP
Sbjct: 905 EDTHVPLEE-VHLVAGPALLTD----ARVRLAEGQGHLESGHP 792
>06576
          Length = 1547

 Score = 31.2 bits (69), Expect = 3.7,   Method: Compositional matrix adjust.
 Identities = 25/89 (28%), Positives = 42/89 (47%), Gaps = 4/89 (4%)
 Frame = -2

Query: 381  FAYSLAFSPVDVGSLAIGVGDGMIRVWNTLSIKNNYDVKNFWQGVKSKVTA----LCWHP 436
            F  S+ FSP +   +     D   RVW     K+  D + + + V  ++TA    +CWH 
Sbjct: 1078 FVNSVTFSPTEEDQVXSTGDDLTCRVWTG---KDGQDGR-YGESVIFRLTAPGMAVCWHA 911

Query: 437  NKEGCLAFGTDDGKVGLYDTCSNKPPQIS 465
            ++   L  G  DG +  + + SN+ P +S
Sbjct: 910  DEPLKLMVGQKDGIIRFF-SLSNQQPIMS 827
>26939
          Length = 388

 Score = 30.8 bits (68), Expect = 4.5,   Method: Composition-based stats.
 Identities = 11/32 (34%), Positives = 20/32 (62%)
 Frame = +2

Query: 84  TSSDDGTVKVWDVETKTVVTEHTLHQHTISAL 115
           ++SDD T++VWD+  K  +     HQH  +++
Sbjct: 17  SASDDKTIRVWDLRNKRCMKTLYAHQHFCTSI 112
>11915
          Length = 737

 Score = 30.8 bits (68), Expect = 4.5,   Method: Compositional matrix adjust.
 Identities = 17/71 (23%), Positives = 33/71 (46%)
 Frame = +1

Query: 83  ATSSDDGTVKVWDVETKTVVTEHTLHQHTISALHWSPTVKDLIVSGDEKGVVFCYWLNRN 142
           AT    G +K+W+ ET  ++ E   H+ T+  LH++      ++S    G V  +  +  
Sbjct: 454 ATGHVSGRIKLWNCETGKLLIEMMDHKATVHDLHFAADNSLCLMSASHDGTVKLWEFDDQ 633

Query: 143 DSQHLFTEPRT 153
              +++   RT
Sbjct: 634 GDCNMYLTLRT 666
>10162
          Length = 1629

 Score = 30.4 bits (67), Expect = 5.0,   Method: Compositional matrix adjust.
 Identities = 23/69 (33%), Positives = 30/69 (43%), Gaps = 2/69 (2%)
 Frame = +3

Query: 638 HTAKITSLAWSPHHDGRLVSACYDGTAQVWDALREEPLFNFRGHRGRLLCVAWSPV--DP 695
           H   +  L WS      L +AC DG  +VWDA          GH  R  C+    V  D 
Sbjct: 639 HPEGVCKLQWSSS-TALLYTACLDGVMRVWDARSGASKAVLTGH-ARNSCILDFDVTRDG 812

Query: 696 ECIYSGADD 704
            C+ SG++D
Sbjct: 813 TCLVSGSED 839
>15745
          Length = 1183

 Score = 30.4 bits (67), Expect = 5.2,   Method: Compositional matrix adjust.
 Identities = 31/144 (21%), Positives = 57/144 (39%), Gaps = 3/144 (2%)
 Frame = +2

Query: 572 CTIQQHHKLVNAIVWHHEHGSRPELSCLLASGSNNAVIYVHNLKAVL-ESNPESPITITE 630
           C +      V  I+WH              +G +  V+ V   + ++ + N  S      
Sbjct: 410 CHLHSSDHDVKGILWH-------------PTGDSQTVLGVCEDRVIMWDLNVASSSAQQT 550

Query: 631 PYRTLSGH-TAKITSLAWSPHHDGRLVSACYDGTAQVWDALREEPLFNFRGHRGRLL-CV 688
              TL G    ++T   W+PHH+   ++   + T + WD   ++  +   G  G+L+  +
Sbjct: 551 DMITLEGKGQPRLTCGRWNPHHNCAQIATANEATIRGWDLRSKQQTYQMEGAHGQLVRDL 730

Query: 689 AWSPVDPECIYSGADDFCVYRWLT 712
            ++P     + S  DD  V  W T
Sbjct: 731 DFNPNRQYYLASCGDDCRVKFWDT 802
>30108
          Length = 1032

 Score = 30.4 bits (67), Expect = 5.5,   Method: Compositional matrix adjust.
 Identities = 26/105 (24%), Positives = 40/105 (38%)
 Frame = +1

Query: 351 LLLSTSMDRDVKCWDMATLECCWTLPSLGGFAYSLAFSPVDVGSLAIGVGDGMIRVWNTL 410
           LL ++ +D  V  W +   E C  L  LGG   SL     D   +       + RVW+T 
Sbjct: 424 LLSASPVDTAVMAWSVGG-EACTALRYLGGGGVSLLACSPDGSKVMAATPATLFRVWDTT 600

Query: 411 SIKNNYDVKNFWQGVKSKVTALCWHPNKEGCLAFGTDDGKVGLYD 455
           S          W  +  + T+ CW           + DG+V ++ 
Sbjct: 601 SWHC-----EVWSQLSGRCTSACW-----------SHDGQVXVFS 687
>11493
          Length = 535

 Score = 30.4 bits (67), Expect = 6.2,   Method: Compositional matrix adjust.
 Identities = 23/65 (35%), Positives = 32/65 (49%), Gaps = 1/65 (1%)
 Frame = -2

Query: 644 SLAWSPHHDGRL-VSACYDGTAQVWDALREEPLFNFRGHRGRLLCVAWSPVDPECIYSGA 702
           +LA SP  D ++  S C DG   VWD   E  +  F+GH     C+  SP D   +++G 
Sbjct: 192 ALAISP--DSKVCFSCCSDGNIAVWDLHNEILVRQFQGHTDGASCIDISP-DGSRLWTGG 22

Query: 703 DDFCV 707
            D  V
Sbjct: 21  LDNTV 7
>00825
          Length = 1821

 Score = 30.4 bits (67), Expect = 6.4,   Method: Compositional matrix adjust.
 Identities = 37/154 (24%), Positives = 60/154 (38%)
 Frame = -2

Query: 554  GNEDGSIEIFQVPNLRLLCTIQQHHKLVNAIVWHHEHGSRPELSCLLASGSNNAVIYVHN 613
            G  DG +  + +P  ++ C +Q H  +V+ +  H     +   SC    GS+  +     
Sbjct: 1817 GACDGELICWNLPKQQMACRVQAHDGIVHGMAAHS--SGQYFFSC----GSDKTI----- 1671

Query: 614  LKAVLESNPESPITITEPYRTLSGHTAKITSLAWSPHHDGRLVSACYDGTAQVWDALREE 673
                   +PE  I   EP  TL       TSL    HH    +         VWD  R E
Sbjct: 1670 --KQWSLDPEGTIA-PEPVNTLLAKCI-YTSL---DHHWKDDIFVTSGSRVDVWDEKRSE 1512

Query: 674  PLFNFRGHRGRLLCVAWSPVDPECIYSGADDFCV 707
            P+ +F      +  V ++PV+   + + A D  +
Sbjct: 1511 PMRSFSWGVESVHHVKFNPVETYLLGAAAHDRSI 1410
>14555
          Length = 627

 Score = 29.6 bits (65), Expect = 9.7,   Method: Composition-based stats.
 Identities = 17/50 (34%), Positives = 25/50 (50%)
 Frame = -3

Query: 661 DGTAQVWDALREEPLFNFRGHRGRLLCVAWSPVDPECIYSGADDFCVYRW 710
           D T  VWDAL+        GH  R+ C+  SP D   + +G+ D+ +  W
Sbjct: 403 DYTVNVWDALKGMRSTILYGHDNRVSCLRISP-DGTSLCTGSWDYTLRIW 257
>32784
          Length = 523

 Score = 29.6 bits (65), Expect = 9.9,   Method: Composition-based stats.
 Identities = 16/40 (40%), Positives = 20/40 (50%)
 Frame = -3

Query: 340 LCSLKTEDGKQLLLSTSMDRDVKCWDMATLECCWTLPSLG 379
           LCS K E    L + T ++R + CW   T   CWT  S G
Sbjct: 122 LCSQKMEG---LTILTKINRTLHCWMTKTTTLCWTWLSSG 12
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|7106389|ref|NP_036099.1| proteasome (prosome,
macropain) subunit, alpha type 7 [Mus musculus]
         (248 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

24591                                                                 376   e-105
02448                                                                 376   e-105
00789                                                                 155   2e-38
20771                                                                 153   8e-38
14551                                                                 145   2e-35
17033                                                                 138   2e-33
04255                                                                  85   1e-23
19133                                                                  91   3e-19
28971                                                                  72   3e-13
11023                                                                  39   0.002
37174                                                                  33   0.11 
09721                                                                  30   1.2  
09881                                                                  29   1.7  
10729                                                                  28   4.3  
>24591
          Length = 1801

 Score =  376 bits (966), Expect = e-105,   Method: Compositional matrix adjust.
 Identities = 175/218 (80%), Positives = 200/218 (91%)
 Frame = +1

Query: 3   YDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGKDIVVLGVEKKSVAKLQDERTVRKI 62
           YDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRG ++VVLGVEKK+VAKLQ+ERTVRKI
Sbjct: 40  YDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGDNLVVLGVEKKAVAKLQEERTVRKI 219

Query: 63  CALDDNVCMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQSN 122
             LD++V +AFAGLTADARI+INRAR+ECQSH+LTVEDPVTVEYITR+IA LKQ+YTQSN
Sbjct: 220 ALLDEHVALAFAGLTADARILINRARIECQSHKLTVEDPVTVEYITRHIAQLKQKYTQSN 399

Query: 123 GRRPFGISALIVGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLEKNYTDDAIE 182
           GRRPFG+S+LI+GFD+DGTP LYQTDPSGTYH WKAN IGR AK+VREFLEK+YTD+   
Sbjct: 400 GRRPFGLSSLIIGFDYDGTPHLYQTDPSGTYHEWKANTIGRNAKTVREFLEKHYTDEVAA 579

Query: 183 TDDLTIKLVIKALLEVVQSGGKNIELAVMRRDQPLKIL 220
           +D  TIKL +KALLEVVQSG KN+E+AVMRR Q L++L
Sbjct: 580 SDKETIKLALKALLEVVQSGAKNMEVAVMRRGQALQML 693
>02448
          Length = 1302

 Score =  376 bits (965), Expect = e-105,   Method: Compositional matrix adjust.
 Identities = 174/218 (79%), Positives = 200/218 (91%)
 Frame = +2

Query: 3   YDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGKDIVVLGVEKKSVAKLQDERTVRKI 62
           YDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRG ++VVLGVEKK+VAKLQ+ERTVRKI
Sbjct: 263 YDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGNNLVVLGVEKKAVAKLQEERTVRKI 442

Query: 63  CALDDNVCMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQSN 122
             LD++V +AFAGLTADARI+INRAR+ECQSH+LTVEDPVTVEYITR+IA LKQ+YTQSN
Sbjct: 443 ALLDEHVALAFAGLTADARILINRARIECQSHKLTVEDPVTVEYITRHIAQLKQKYTQSN 622

Query: 123 GRRPFGISALIVGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLEKNYTDDAIE 182
           GRRPFG+S+LI+GFD+DG+P LYQTDPSGTYH WKAN IGR AK+VREFLEK+YTD+   
Sbjct: 623 GRRPFGLSSLIIGFDYDGSPHLYQTDPSGTYHEWKANTIGRNAKTVREFLEKHYTDEVAA 802

Query: 183 TDDLTIKLVIKALLEVVQSGGKNIELAVMRRDQPLKIL 220
           +D  TIKL +KALLEVVQSG KN+E+AVMRR Q L++L
Sbjct: 803 SDKETIKLALKALLEVVQSGAKNMEVAVMRRGQALQML 916
>00789
          Length = 1584

 Score =  155 bits (391), Expect = 2e-38,   Method: Compositional matrix adjust.
 Identities = 80/215 (37%), Positives = 127/215 (59%), Gaps = 4/215 (1%)
 Frame = +1

Query: 3   YDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGKDIVVLGVEKKSVAKLQDERTV-RK 61
           YD   T+FSP+G L+QVEYA EA+    T +G+  KD +VL  E+++  KL DE +   K
Sbjct: 34  YDSRTTIFSPEGRLYQVEYAMEAIGHAGTCLGILAKDGIVLAAERRNTNKLLDEVSYSEK 213

Query: 62  ICALDDNVCMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQS 121
           I  L D++  + AG+T+DA ++ N  R+  Q + L  ++P+  E +   +  +KQ YTQ 
Sbjct: 214 IYRLSDDMACSVAGITSDANVLTNELRLIAQRYLLQYQEPIPCEQVVATLCDIKQAYTQF 393

Query: 122 NGRRPFGISALIVGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLEKNYTDDAI 181
            G+RPFG+S L +G+D     +LYQ+DPSG Y  WKA  IG  + +    L++ Y +D  
Sbjct: 394 GGKRPFGVSILYMGWDKHYGFQLYQSDPSGNYGGWKATCIGNNSANAVSLLKQEYKEDES 573

Query: 182 ETDD---LTIKLVIKALLEVVQSGGKNIELAVMRR 213
             D+   L+IK++ K  L++ +     +E+A + R
Sbjct: 574 SLDEALALSIKVLGKT-LDLTKLTPDKVEMATLTR 675
>20771
          Length = 674

 Score =  153 bits (386), Expect = 8e-38,   Method: Compositional matrix adjust.
 Identities = 75/179 (41%), Positives = 117/179 (65%), Gaps = 5/179 (2%)
 Frame = +2

Query: 3   YDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGKDIVVLGVEKKSVAKLQDERTVRKI 62
           YDR +  FSP+G LFQVEYA EA+K GSTA+G++  + VVL VEK+  + L +  ++ KI
Sbjct: 101 YDRGVNTFSPEGRLFQVEYAIEAIKLGSTAIGIQTNEGVVLAVEKRVTSSLIEPTSIEKI 280

Query: 63  CALDDNVCMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQSN 122
             +D ++  A +GL AD+R +I+RARVE Q+H  T  + ++VE +T+ +++L   +   +
Sbjct: 281 MEVDKHIGCAMSGLIADSRTLIDRARVEAQNHWFTYNENMSVESVTQAVSNLALAFGDDD 460

Query: 123 G-----RRPFGISALIVGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLEKNY 176
                  RPFG++ LI G D +G PRL+  DPSGT+  + A AIG G++  ++ L++ Y
Sbjct: 461 PDPGAMSRPFGVALLIAGVDSNG-PRLFHMDPSGTFIQYDAKAIGSGSEGAQQALQEQY 634
>14551
          Length = 1344

 Score =  145 bits (365), Expect = 2e-35,   Method: Compositional matrix adjust.
 Identities = 80/228 (35%), Positives = 127/228 (55%), Gaps = 11/228 (4%)
 Frame = +3

Query: 3   YDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGKDIVVLGVEKKSVAKLQDERTVRKI 62
           Y  ++T FSP G L Q+EYA  AV  G+ +VG++  + VVL  EKK  +   DE ++ K+
Sbjct: 153 YSFSLTTFSPSGKLVQIEYALAAVGAGAPSVGIKATNGVVLATEKKQKSVXYDEHSINKV 332

Query: 63  CALDDNVCMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQSN 122
             +  N+ + ++G+  D R++  RAR   + ++    + +    + + +A++ Q +TQS 
Sbjct: 333 ETITKNIGIVYSGMGPDYRVLCRRARKLAEQYKRVYNEQIPTAQLVQRVAAVMQEFTQSG 512

Query: 123 GRRPFGISALIVGFDF-DGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLEKNYT---- 177
           G RPFG+S L+ G+D  D  P LYQ DPSG Y AWKA A+G+   + + FLEK Y+    
Sbjct: 513 GVRPFGVSLLMAGWDEDDKKPFLYQCDPSGAYFAWKATAMGKNHINGKTFLEKRYSETLE 692

Query: 178 -DDAIETDDLTIKLVIKALLEVVQSGGKNIELAV-----MRRDQPLKI 219
            +DA+ T  L +K   +      Q    NIE+ +      RR +P +I
Sbjct: 693 LEDAVHTAILALKESFEG-----QMTEDNIEIGICNSSGFRRLEPSEI 821
>17033
          Length = 2217

 Score =  138 bits (347), Expect = 2e-33,   Method: Compositional matrix adjust.
 Identities = 71/197 (36%), Positives = 120/197 (60%)
 Frame = -3

Query: 3    YDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGKDIVVLGVEKKSVAKLQDERTVRKI 62
            YD + + FSPDG +FQVEYAQ+AV+   TA+G+RGKD VV+GVEK   +KL ++   +++
Sbjct: 2149 YDLSASHFSPDGRVFQVEYAQKAVENSGTAIGIRGKDGVVMGVEKLVTSKLYEQGANKRL 1970

Query: 63   CALDDNVCMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQSN 122
              +D ++  A AGL ADAR ++ RA+ E  ++R     PV ++Y+T  +A     YT  +
Sbjct: 1969 FNIDRHIGGAVAGLLADARQLMERAKEESSNYRFNYGSPVPLKYLTDRVAGYVHAYTLHS 1790

Query: 123  GRRPFGISALIVGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLEKNYTDDAIE 182
              RPFG S ++  +D  G P+++  +PSG    +   AIG+  ++ +  +EK      ++
Sbjct: 1789 AVRPFGTSMIVASYDAVG-PQMFLVEPSGVSWGYYGCAIGKAKQTAKTEIEK------LK 1631

Query: 183  TDDLTIKLVIKALLEVV 199
              DLT++ ++K +  ++
Sbjct: 1630 MKDLTMQDLVKEVARII 1580
>04255
          Length = 1758

 Score = 84.7 bits (208), Expect(2) = 1e-23,   Method: Compositional matrix adjust.
 Identities = 49/167 (29%), Positives = 84/167 (50%), Gaps = 2/167 (1%)
 Frame = -2

Query: 52   KLQDERTVRKICALDDNVCMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYI 111
            KL D  TV  + +L + +     G+ AD++  + RAR E    + T    + V+ + + I
Sbjct: 1457 KLLDPTTVTHLYSLTERIGCVMTGMIADSQSQVQRARYEAAKWKYTYGYDIPVDMLCKRI 1278

Query: 112  ASLKQRYTQSNGRRPFGISALIVGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREF 171
            A++ Q YTQS   RP G   +++G+D +  P +Y+TDP+G Y  +KA + G        F
Sbjct: 1277 ANINQVYTQSAEMRPLGCCMILIGYDDEKGPEVYKTDPAGYYCGFKATSAGSKQLEANGF 1098

Query: 172  LEKNYTDDAIETDDLTIKLVIKALLEVVQSGGK--NIELAVMRRDQP 216
            LEK        T +   ++ I  L  V+ +  K   +E+ ++ +D P
Sbjct: 1097 LEKKIKKKQDFTYNEAAEIAITCLSTVLSADFKASEVEVGIVTKDNP 957

 Score = 42.0 bits (97), Expect(2) = 1e-23,   Method: Compositional matrix adjust.
 Identities = 21/40 (52%), Positives = 29/40 (72%), Gaps = 1/40 (2%)
 Frame = -3

Query: 10   FSPDGHLFQVEYAQEAVKKGS-TAVGVRGKDIVVLGVEKK 48
             SP+G L+QVEYA +A+ +G  T+V VRGKD  V+  +KK
Sbjct: 1585 LSPEGRLYQVEYAFKAINQGGLTSVAVRGKDSAVIVTQKK 1466
>19133
          Length = 692

 Score = 91.3 bits (225), Expect = 3e-19,   Method: Compositional matrix adjust.
 Identities = 53/150 (35%), Positives = 80/150 (53%), Gaps = 4/150 (2%)
 Frame = +1

Query: 76  LTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQSNGRRPFGISALIVG 135
           LTADAR++ N  + EC   R   + P+ V  +   I +  Q  T   GRRPFG+  LI G
Sbjct: 1   LTADARLLCNFMQTECLDSRWAYQQPLPVSRLVSAIGNKLQIPTHRYGRRPFGVGLLIAG 180

Query: 136 FDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLEKNYTDDAIETDDLTIKLVIKAL 195
           +D+ G P +YQT PS  Y+  KA AIG  ++S R +LE++       + D  +K  ++AL
Sbjct: 181 YDWSG-PHIYQTCPSANYYDCKAMAIGARSQSARTYLERHLDQFPQCSLDELVKHGLRAL 357

Query: 196 LEVVQS----GGKNIELAVMRRDQPLKILN 221
            + + S      KN  L ++ +D   KI +
Sbjct: 358 RDTLPSEVTLSTKNCSLGIVDKDMKFKIYD 447
>28971
          Length = 437

 Score = 71.6 bits (174), Expect = 3e-13,   Method: Compositional matrix adjust.
 Identities = 34/59 (57%), Positives = 42/59 (71%)
 Frame = +1

Query: 116 QRYTQSNGRRPFGISALIVGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLEK 174
           Q YTQS G RPFG+S LI G+D +  P LYQ+DPSG Y AWKA A+G+ A + + FL K
Sbjct: 4   QEYTQSGGVRPFGVSLLICGWDNE-RPYLYQSDPSGAYFAWKATAMGKNAVNGKNFLGK 177
>11023
          Length = 1057

 Score = 38.9 bits (89), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 19/47 (40%), Positives = 28/47 (59%), Gaps = 1/47 (2%)
 Frame = -2

Query: 129  ISALI-VGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLEK 174
            IS +I +G+D +  P +Y+TDP+G Y  +KA + G        FLEK
Sbjct: 1005 ISGMILIGYDDEKGPEVYKTDPAGYYCGFKATSAGSKQLEANGFLEK 865
>37174
          Length = 146

 Score = 33.1 bits (74), Expect = 0.11,   Method: Compositional matrix adjust.
 Identities = 17/42 (40%), Positives = 22/42 (52%)
 Frame = +1

Query: 3  YDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGKDIVVLG 44
          Y R      P   L Q+EYA  AV  G+  VG++  + VVLG
Sbjct: 16 YKRVYNEQIPTAQLVQIEYALAAVGAGAPVVGIKATNGVVLG 141
>09721
          Length = 919

 Score = 29.6 bits (65), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 13/38 (34%), Positives = 20/38 (52%)
 Frame = -1

Query: 76  LTADARIVINRARVECQSHRLTVEDPVTVEYITRYIAS 113
           LTADAR++ N  + EC   R   + P+ V  +   I +
Sbjct: 919 LTADARLLCNFMQTECLDSRWAYQQPLPVSRLVSAIGN 806
>09881
          Length = 600

 Score = 29.3 bits (64), Expect = 1.7,   Method: Compositional matrix adjust.
 Identities = 19/48 (39%), Positives = 22/48 (45%), Gaps = 3/48 (6%)
 Frame = +3

Query: 63  CALDDNVCMAFAGLTADARIVINRARVECQSHR---LTVEDPVTVEYI 107
           C +    C A  G +A   IV N     C   R   LT EDPVT EY+
Sbjct: 288 CVVAFTACDAEVGASAKQGIVSNVKNTVCNVKRILGLTFEDPVTQEYL 431
>10729
          Length = 363

 Score = 27.7 bits (60), Expect = 4.3,   Method: Compositional matrix adjust.
 Identities = 12/15 (80%), Positives = 14/15 (93%)
 Frame = +1

Query: 33  VGVRGKDIVVLGVEK 47
           VGVRG ++VVLGVEK
Sbjct: 319 VGVRGNNLVVLGVEK 363
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|80861454|ref|NP_001031761.1| plasma membrane calcium
ATPase 2 isoform 2 [Mus musculus]
         (1198 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

12151                                                                 251   e-105
06342                                                                 241   1e-63
29829                                                                 200   3e-51
00499                                                                 199   6e-51
21541                                                                 142   9e-34
36566                                                                 115   7e-26
35407                                                                 114   3e-25
08160                                                                  65   2e-10
28890                                                                  59   1e-08
14773                                                                  51   3e-06
04985                                                                  48   2e-05
13525                                                                  43   0.001
33697                                                                  39   0.013
07486                                                                  38   0.021
14321                                                                  37   0.051
06247                                                                  31   3.1  
26294                                                                  30   6.4  
>12151
          Length = 880

 Score =  251 bits (642), Expect(2) = e-105,   Method: Compositional matrix adjust.
 Identities = 135/198 (68%), Positives = 151/198 (76%), Gaps = 4/198 (2%)
 Frame = +3

Query: 784 KKADVGFAMGIAGTDVAKEASDIILTDDNFSSIVKAVMWGRNVYDSISKFLQFQLTVNVV 843
           +KADVGFAMGI+GTDVAKEASDIILTDDNF+SIVKAVMWGRNVYDSI+KFLQFQLTVNVV
Sbjct: 288 QKADVGFAMGISGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSIAKFLQFQLTVNVV 467

Query: 844 AVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASXXXXXXXXXXXXXXRKPYGRNKPLIS 903
           AV VAF GAC   DSPLKA+QMLWVNLIMDT AS              R+PYGR KPLIS
Sbjct: 468 AVFVAFVGACSIGDSPLKAIQMLWVNLIMDTLASLALATELPSSELLKRRPYGRTKPLIS 647

Query: 904 RTMMKNILGHAVYQLTLIFTLLFVGEKMF----QIDSGRNAPLHSPPSEHYTIIFNTFVM 959
           +TM KNILGHA YQ+ +I  LLF G K         + R  P   P ++H+TIIFN FVM
Sbjct: 648 KTMWKNILGHAFYQILVILLLLFQGAKAVWDRRWHPTSRETP--RPTNQHFTIIFNAFVM 821

Query: 960 MQLFNEINARKIHGERNV 977
           M LFNE+NARKIH +RN+
Sbjct: 822 MTLFNEVNARKIHDQRNI 875

 Score =  149 bits (376), Expect(2) = e-105,   Method: Compositional matrix adjust.
 Identities = 70/98 (71%), Positives = 83/98 (84%)
 Frame = +1

Query: 688 DNINTARAIAIKCGIIHPGEDFLCLEGKEFNRRIRNEKGEIEQERIDKIWPKLRVLARSS 747
           DN+NTAR+IA KCGII PG+D L LEGKEFN+ IR+ +GEI QE++D++WP LRVLARSS
Sbjct: 1   DNVNTARSIASKCGIIQPGDDGLVLEGKEFNQLIRDAEGEISQEKVDEVWPNLRVLARSS 180

Query: 748 PTDKHTLVKGIIDSTHTEQRQVVAVTGDGTNDGPALKK 785
           P DK+ LVK IIDS  +  R+VVAVTGDGTNDGPALKK
Sbjct: 181 PQDKYILVKHIIDSKVSTSREVVAVTGDGTNDGPALKK 294
>06342
          Length = 2428

 Score =  241 bits (615), Expect = 1e-63,   Method: Compositional matrix adjust.
 Identities = 218/739 (29%), Positives = 344/739 (46%), Gaps = 69/739 (9%)
 Frame = +2

Query: 208 IVVGDIAQIKYGDLLPADG--LFIQGNDLKIDESSLTGESDQVRKSVDKDP--------- 256
           +V GDI ++  GD +PAD   L I    L+ID++ LTGES  V K  D  P         
Sbjct: 5   LVPGDIVEVSVGDKVPADIRILKIHSTTLRIDQAILTGESVSVMKHTDPIPDPRAVNQDK 184

Query: 257 --MLLSGTHVMEGSGRMVVTAVGVNSQTGIIFTLLXXXXXXXXXXXXXXXXXXXXXXMEM 314
             +L SGT+V  G  + +V   G+ ++ G I                             
Sbjct: 185 KNLLFSGTNVAAGKCKGLVIGTGLTTEIGKI----------------------------- 277

Query: 315 QPLKSAEGGDADDKKKANMHKKEKSVLQGKLTKLAVQIGKAGLVMSAITVIILVLYFTVD 374
                        + +    ++EK+ LQ KL + + Q+ K       +  II +  + ++
Sbjct: 278 -------------RNEMMDTEQEKTPLQQKLDEFSNQLSK-------VITIICIAVWAIN 397

Query: 375 TFVVNKKPWLTECTPVYVQYFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNN 434
               N           +++  + +F I V + V A+PEGLP  +T  LA   ++M K N 
Sbjct: 398 IGHFNDPAHGGS----WIKGAIYYFKIAVALAVAAIPEGLPAVITTCLALGTRRMAKKNA 565

Query: 435 LVRHLDACETMGNATAICSDKTGTLTTNRMTVVQAYVGDVHYKEIPDPSSINAKTLELLV 494
           +VR L + ET+G  + ICSDKTGTLTTN+M+V + ++    + +I D + I     E+  
Sbjct: 566 IVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCKLFI----FSQI-DTNQIKTTQFEVTG 730

Query: 495 NAIAINSAYTTKILPPEKEGALPRQVGNKTECGLLGFVLDLRQDYEPVRSQMPE------ 548
           +  A +     ++    K+       G +  C + G   D   DY   ++Q  +      
Sbjct: 731 STYAPDG----ELYQNGKKVKASDYPGLEELCTICGMCNDSSVDYNEAKTQYEKVGEATE 898

Query: 549 -------EKL---------------------------YKVYT--FNSVRKSMSTVIKMPD 572
                  EKL                            K +T  F+  RKSMS V  +P+
Sbjct: 899 TALTVLAEKLNFYNTDKSSLNKREMGTVCNHVIQDMWRKEFTLEFSRDRKSMS-VFCVPN 1075

Query: 573 E------SFRMYSKGASEIVLKKCCKILSGAGEARVFRPRDRDEMVKKV-IEPMACDGLR 625
           +        RM++KGA E +L +C  +  G  +  +  P  ++E++K   I     D LR
Sbjct: 1076KPTRVPGGARMFAKGAPEGLLDRCTHVRIGNNKVPM-SPAIKNEIMKLTKIYGTGRDTLR 1252

Query: 626 TICVAYRDFPSSPEPDWDNEN-----DILNELTCICVVGIEDPVRPEVPEAIRKCQRAGI 680
            + +A  D P   E D D E+     +    +T + VVG+ DP R EV  +I+ C+ AGI
Sbjct: 1253CLALATIDNPPRRE-DMDLEDSRKFIEYETNMTFVGVVGMLDPPREEVMASIKNCRAAGI 1429

Query: 681 TVRMVTGDNINTARAIAIKCGIIHPGEDF--LCLEGKEFNRRIRNEKGEIEQERIDKIWP 738
            V ++TGDN  TA AI  + G+    E+   L   G+EF+        E+  E       
Sbjct: 1430RVIVITGDNKATAEAICRRIGVFSESENTEGLAYTGREFD--------ELPPEDQRAAVM 1585

Query: 739 KLRVLARSSPTDKHTLVKGIIDSTHTEQRQVVAVTGDGTNDGPALKKADVGFAMGIAGTD 798
           + R+ AR  P  K  +V+ +       + ++ A+TGDG ND PALKKA++G AMG +GT 
Sbjct: 1586RARLFARVEPAHKSKIVEYL-----QAEGEISAMTGDGVNDAPALKKAEIGIAMG-SGTA 1747

Query: 799 VAKEASDIILTDDNFSSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDS 858
           VAK AS+++L DDNFS+IV AV  GR +Y+++ +F+++ ++ N+  V+  F  A +    
Sbjct: 1748VAKSASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNIGEVVCIFLTAALGIPE 1927

Query: 859 PLKAVQMLWVNLIMDTFAS 877
            L  VQ+LWVNL+ D F +
Sbjct: 1928ALIPVQLLWVNLVTDGFPA 1984
>29829
          Length = 465

 Score =  200 bits (508), Expect = 3e-51,   Method: Compositional matrix adjust.
 Identities = 106/150 (70%), Positives = 118/150 (78%)
 Frame = -3

Query: 788 VGFAMGIAGTDVAKEASDIILTDDNFSSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIV 847
           +GFAMGI+GTDVAKEASDIILTDDNF+SIVKAV WGRNVYDSI+KFLQFQLTVNVVAV V
Sbjct: 460 LGFAMGISGTDVAKEASDIILTDDNFTSIVKAVXWGRNVYDSIAKFLQFQLTVNVVAVFV 281

Query: 848 AFTGACITQDSPLKAVQMLWVNLIMDTFASXXXXXXXXXXXXXXRKPYGRNKPLISRTMM 907
           AF GAC   DSPL+A+QMLWVNLIMDT AS              RKPYGR KPLIS+TM 
Sbjct: 280 AFVGACSIGDSPLEAIQMLWVNLIMDTLASLALATELPSNELLKRKPYGRTKPLISKTMF 101

Query: 908 KNILGHAVYQLTLIFTLLFVGEKMFQIDSG 937
           KNI GH+VYQ+ +I  +LF G  +F ID G
Sbjct: 100 KNIAGHSVYQIIIILVILFKGADLFGIDDG 11
>00499
          Length = 4026

 Score =  199 bits (505), Expect = 6e-51,   Method: Compositional matrix adjust.
 Identities = 180/572 (31%), Positives = 269/572 (47%), Gaps = 49/572 (8%)
 Frame = +2

Query: 413 GLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTTNRMTVVQAYV- 471
           GL   VT+ L  + K+M + N LV++L+A ET+G+ + ICSDKTGTLT NRMTV   +  
Sbjct: 2   GLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFD 181

Query: 472 ------------GDVHYKEIPDPSSINAKTLELLVNAIAINSAY-TTKILPPEKEGALPR 518
                        +  Y    DP+ +    + +L N            IL  E  G    
Sbjct: 182 GRIVEADTSDDQSNATYSR-SDPTWMALSRVAMLCNRAEFKGNQDNVPILKRECNGDASE 358

Query: 519 QVGNKTECGLLGFVLDLRQDYEPVRSQMPEEKLYKVYTFNSVRKSMSTVIKM--PDE-SF 575
               K     +G V + R+  E +  ++P         FNS  K   ++ +   PD+  +
Sbjct: 359 SALLKCVELSIGHVTEYRRRNEKI-VEIP---------FNSSNKYQVSIHETEDPDDPRY 508

Query: 576 RMYSKGASEIVLKKCCKILSGAGEARVFRPRDRDEMVKKVIEPMACDGLRTICVAYRD-- 633
            +  KGA E ++ +C  IL    E    +P D +         +   GL    + + D  
Sbjct: 509 LLVMKGAPERIMDRCSTILLNGKE----QPLDDNFREAFNAAYLELGGLGERVLGFCDYF 676

Query: 634 -----FPSSPEPDWDNENDILNELTCICVVGIEDPVRPEVPEAIRKCQRAGITVRMVTGD 688
                FP   E D +  N  +  L  + ++ + DP R  VP+A+ KC+ AGI V MVTGD
Sbjct: 677 LPVDQFPPGYEFDPEGPNFPITGLRFVGLMAMIDPPRAAVPDAVGKCRSAGIKVIMVTGD 856

Query: 689 NINTARAIAIKCGIIHPG----EDFLCLEG---KEFNRRIRN----EKGEIEQERIDKIW 737
           +  TA+AIA   GII  G    ED     G   +E + R         G++      +I 
Sbjct: 857 HPITAKAIARGVGIISEGSKTVEDIASERGIPVEEVDPREAKAAVIHGGDLRDMTPAQID 1036

Query: 738 PKLR-----VLARSSPTDKHTLVKGIIDSTHTEQRQVVAVTGDGTNDGPALKKADVGFAM 792
             LR     V AR+SP  K  +V+G        Q Q+VAVTGDG ND PALKKAD+G AM
Sbjct: 1037EILRNHSEIVFARTSPQQKLIIVEGC-----QRQGQIVAVTGDGVNDSPALKKADIGVAM 1201

Query: 793 GIAGTDVAKEASDIILTDDNFSSIVKAVMWGRNVYDSISKFLQFQLTVNV--VAVIVAFT 850
           GIAG+DV+K+A+D+IL DDNF+SIV  V  GR ++D++ K + + LT N+  ++  + F 
Sbjct: 1202GIAGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEISPFLLFI 1381

Query: 851 GACITQDSPLKAVQMLWVNLIMDTFASXXXXXXXXXXXXXXRKPYGRNKPLISRTMMKNI 910
            A I    PL  + +L ++L  D   +              R+P     P+  + + + +
Sbjct: 1382LADIPL--PLGTITILCIDLGTDMVPAISLAYEKAENDIMKRQP---RDPVKDKLVNERL 1546

Query: 911 LGHAVYQLTLI------FT-LLFVGEKMFQID 935
           +  A  Q+ +I      FT  + +GE  F  D
Sbjct: 1547ISMAYGQIGMIQASAGFFTYFVIMGENGFWYD 1642
>21541
          Length = 445

 Score =  142 bits (357), Expect = 9e-34,   Method: Compositional matrix adjust.
 Identities = 73/122 (59%), Positives = 84/122 (68%)
 Frame = +3

Query: 168 TAFNDWSKEKQFRGLQSRIEQEQKFTVVRAGQVVQIPVAEIVVGDIAQIKYGDLLPADGL 227
           TAFNDWSKEKQFRGLQS+IE E +FTV+R G++ QIPV EI+VG+I QIKYGDLLPADG+
Sbjct: 54  TAFNDWSKEKQFRGLQSKIEHEHRFTVIRNGELHQIPVGEILVGEICQIKYGDLLPADGV 233

Query: 228 FIQGNDLKIDESSLTGESDQVRKSVDKDPMLLSGTHVMEGSGRMVVTAVGVNSQTGIIFT 287
            IQ NDLK     +        K   + P          G  +MVVTAVGVNSQTGIIF 
Sbjct: 234 IIQSNDLKNRREFVNRRVGPCEKGRGQGPHAFVRHPCNGGQWKMVVTAVGVNSQTGIIFA 413

Query: 288 LL 289
           LL
Sbjct: 414 LL 419
>36566
          Length = 589

 Score =  115 bits (289), Expect = 7e-26,   Method: Compositional matrix adjust.
 Identities = 55/147 (37%), Positives = 93/147 (63%)
 Frame = +3

Query: 769 VVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFSSIVKAVMWGRNVYD 828
           VV +TGDG ND  ALK A++G +MG++GTDV+KEASD+IL DD+F++I+ A+  G+ ++ 
Sbjct: 126 VVGMTGDGVNDAVALKSAEIGISMGVSGTDVSKEASDMILVDDDFTTILNAIEEGKGIFY 305

Query: 829 SISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASXXXXXXXXXXX 888
           +I  F++FQL+ ++ A+ +      +   +PL A+Q+LW+N+IMD   +           
Sbjct: 306 NIRNFVRFQLSTSIAALSLIAVSTLLRLPNPLNAMQILWINIIMDGPPAQSLGVEPVDHD 485

Query: 889 XXXRKPYGRNKPLISRTMMKNILGHAV 915
              + P     P+I+R ++ N+L  A+
Sbjct: 486 VIKQPPRHVGDPIITRRLIINVLSSAL 566
>35407
          Length = 562

 Score =  114 bits (284), Expect = 3e-25,   Method: Compositional matrix adjust.
 Identities = 78/162 (48%), Positives = 96/162 (59%), Gaps = 3/162 (1%)
 Frame = +1

Query: 57  CRRLKTSPVEGLPGTAPDL--EKRKQIFGQNFIPPKKPKTFLQLVWEALQDVTXXXXXXX 114
            ++LKTSP EGL G   DL  E+R + +G N IPPK PK+FL+LVWEALQDVT       
Sbjct: 85  VQKLKTSPTEGLVG---DLGKEERVRFYGSNVIPPKPPKSFLRLVWEALQDVTLLILIVA 255

Query: 115 XXXXXXXXFYHPPGESNEGCXXXXXXXXXXXXXXXXX-XXXXXILLSVICVVLVTAFNDW 173
                   FY    E +E                         IL++V  VVLVTAFNDW
Sbjct: 256 AIISLGLSFYKGDEEEDETEDESYRAKADSSLEEKVGWIDGLAILVAVAVVVLVTAFNDW 435

Query: 174 SKEKQFRGLQSRIEQEQKFTVVRAGQVVQIPVAEIVVGDIAQ 215
           SKEKQFRGLQS+IE E +FTV+R G++ QIPV +I+VG+I Q
Sbjct: 436 SKEKQFRGLQSKIEHEHRFTVIRDGELHQIPVGDILVGEICQ 561

 Score = 30.0 bits (66), Expect = 6.1,   Method: Composition-based stats.
 Identities = 15/39 (38%), Positives = 20/39 (51%)
 Frame = +2

Query: 29 EELRSLMELRGTEAVVKIKETYGDTEAICRRLKTSPVEG 67
          +ELR LME R  EA   I   YG    +C+  K  P++ 
Sbjct: 2  QELRELMEHRSHEAYNIIATKYGGVLEMCKS*KRHPLKA 118
>08160
          Length = 459

 Score = 64.7 bits (156), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 30/58 (51%), Positives = 41/58 (70%)
 Frame = +2

Query: 413 GLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTTNRMTVVQAY 470
           GL   VT+ L  + K+M + N LV++L+A ET+G+ + ICSDKTGTLT NRMTV   +
Sbjct: 2   GLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMW 175
>28890
          Length = 552

 Score = 59.3 bits (142), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 38/107 (35%), Positives = 58/107 (54%), Gaps = 8/107 (7%)
 Frame = -3

Query: 190 QKFTVVRAGQVVQIPVAEIVVGDIAQIKYGDLLPADGLFIQGNDLKIDESSLTGESDQVR 249
           Q   VVR  Q + +   E+VVGDI + K+GD +PAD   I  +  K+D SSLTGES+   
Sbjct: 475 QFAVVVRGDQKLSVKAEELVVGDIVECKFGDRVPADLRVISAHGFKVDNSSLTGESEPQS 296

Query: 250 KSVD---KDPM-----LLSGTHVMEGSGRMVVTAVGVNSQTGIIFTL 288
           +S +   ++P+         T+ +EG+ R +V   G ++  G I  L
Sbjct: 295 RSAEFTHENPLETRNICFFSTNAVEGTCRGIVIKTGDDTVMGRIANL 155
>14773
          Length = 794

 Score = 50.8 bits (120), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 27/77 (35%), Positives = 46/77 (59%)
 Frame = +2

Query: 797 TDVAKEASDIILTDDNFSSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQ 856
           +DV+K+A+D+IL DDNF+SIV  V  GR ++D++ K + + LT N+  +           
Sbjct: 2   SDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEISPFLVYILFGT 181

Query: 857 DSPLKAVQMLWVNLIMD 873
             PL  + +L+++L  D
Sbjct: 182 PLPLGVITILFIDLGTD 232
>04985
          Length = 1671

 Score = 47.8 bits (112), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 68/288 (23%), Positives = 117/288 (40%), Gaps = 16/288 (5%)
 Frame = -1

Query: 731  ERIDKIWPKLRVLARSSPTDKHTLVKGIIDSTHTEQRQVVAVTGDGTNDGPALKKADVGF 790
            E + K+  +  V AR +P  K  L++ +    +     +V + GDG ND  ALK A  G 
Sbjct: 1641 ELLPKVCTQGTVFARMAPDQKCALIENLQSYDY-----IVGMCGDGANDCEALKAAHAGI 1477

Query: 791  AMGIAGTDVAKEASDIILTDDNFSSIVKAVMWGRNV---------YDSISKFLQFQLTVN 841
            ++  A   VA   +  I   +N   +V A+  GR           Y ++  F+QF     
Sbjct: 1476 SLSEAEASVAAPFTSRI---NNIECVVTAMREGRAALVTSFGCFKYMALYSFIQF----- 1321

Query: 842  VVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASXXXXXXXXXXXXXXRKPYGRNKPL 901
             ++V++ +T  C T  S L   + L+++LI+ T                      R+KP 
Sbjct: 1320 -ISVLILYT--CQTNLSDL---EFLYIDLIITT------TIAVLLGYTGAYDKLVRHKPP 1177

Query: 902  ISRTMMKNILG-------HAVYQLTLIFTLLFVGEKMFQIDSGRNAPLHSPPSEHYTIIF 954
             S   + NI+         A YQL+   TL ++  ++F  +   +       +   TIIF
Sbjct: 1176 DSLMKLSNIISILMQVTLTAAYQLS---TLFYLRSQLFYQNQEVDPLRDETDAWESTIIF 1006

Query: 955  NTFVMMQLFNEINARKIHGERNVFDGIFRNPIFCTIVLGTFAIQIVIV 1002
             T   M +   ++  K           FR PI+  +    F + I+++
Sbjct: 1005 LTSTFMYVSVAVSFSK--------GPPFRKPIYTNV---PFLVSIIVL 895
>13525
          Length = 645

 Score = 42.7 bits (99), Expect = 0.001,   Method: Composition-based stats.
 Identities = 17/33 (51%), Positives = 26/33 (78%)
 Frame = +2

Query: 425 SVKKMMKDNNLVRHLDACETMGNATAICSDKTG 457
           + K+M + N LV++L+A ET+G+ + ICSDKTG
Sbjct: 5   TAKRMARKNCLVKNLEAVETLGSTSTICSDKTG 103
>33697
          Length = 310

 Score = 38.9 bits (89), Expect = 0.013,   Method: Composition-based stats.
 Identities = 18/34 (52%), Positives = 24/34 (70%)
 Frame = -2

Query: 662 DPVRPEVPEAIRKCQRAGITVRMVTGDNINTARA 695
           DP R  VP+A+ KC+ AGI V MVTGD+  T++ 
Sbjct: 195 DPPRAAVPDAVGKCRSAGIKVIMVTGDHPITSQG 94
>07486
          Length = 763

 Score = 38.1 bits (87), Expect = 0.021,   Method: Composition-based stats.
 Identities = 20/43 (46%), Positives = 27/43 (62%)
 Frame = -1

Query: 782 ALKKADVGFAMGIAGTDVAKEASDIILTDDNFSSIVKAVMWGR 824
           AL +ADVG A+G  GTDVA EA+DI+L   +   +  A+   R
Sbjct: 742 ALAQADVGIAIG-TGTDVAVEAADIVLMKSDLVDVYAAIKLSR 617
>14321
          Length = 568

 Score = 37.0 bits (84), Expect = 0.051,   Method: Compositional matrix adjust.
 Identities = 23/57 (40%), Positives = 30/57 (52%)
 Frame = +2

Query: 736 IWPKLRVLARSSPTDKHTLVKGIIDSTHTEQRQVVAVTGDGTNDGPALKKADVGFAM 792
           + P  RV AR +P  K  ++     +    Q  V  + GDGTND  ALK ADVG A+
Sbjct: 248 LLPNTRVFARVAPKQKELII-----TVLKAQGFVTLMCGDGTNDVGALKHADVGVAL 403
>06247
          Length = 458

 Score = 30.8 bits (68), Expect = 3.1,   Method: Compositional matrix adjust.
 Identities = 17/44 (38%), Positives = 25/44 (56%)
 Frame = +2

Query: 988  CTIVLGTFAIQIVIVQFGGKPFSCSPLQLDQWMWCIFIGLGELV 1031
            C+ V G ++  I  V  GG+  +CSP Q++QW  C   GL  +V
Sbjct: 239  CSKVSGGYSTNIENVPQGGR--TCSP*QVNQWRTCEPRGLQGIV 364
>26294
          Length = 430

 Score = 30.0 bits (66), Expect = 6.4,   Method: Composition-based stats.
 Identities = 11/22 (50%), Positives = 12/22 (54%)
 Frame = -3

Query: 1005 GGKPFSCSPLQLDQWMWCIFIG 1026
            GG P SC    LD W WC  +G
Sbjct: 98   GGSPQSCQSCCLDCWAWCCPLG 33
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|50345978|ref|NP_001002012.1| heat shock protein 2
[Mus musculus]
         (633 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

30255                                                                 280   e-104
21024                                                                 218   7e-57
27378                                                                 194   1e-49
26390                                                                 164   1e-40
37715                                                                 147   1e-35
24750                                                                 139   3e-33
06909                                                                  99   2e-24
31218                                                                  89   5e-18
09881                                                                  87   2e-17
20979                                                                  86   3e-17
12271                                                                  64   2e-10
13684                                                                  55   6e-08
03996                                                                  52   7e-07
34036                                                                  50   3e-06
13300                                                                  49   5e-06
>30255
          Length = 1761

 Score =  280 bits (716), Expect(2) = e-104,   Method: Compositional matrix adjust.
 Identities = 143/200 (71%), Positives = 154/200 (77%)
 Frame = -1

Query: 331  KGQIQEIVLVGGSTRIPKIQKLLQDFFNGKELNKSINPDEXXXXXXXXXXXILIGDKSEN 390
            K  I EIVLVGGSTRIPKIQKLLQDFFNGKEL KSINPDE           IL GDKSE 
Sbjct: 1644 KPGIHEIVLVGGSTRIPKIQKLLQDFFNGKELCKSINPDEAVAYGACVQAAILHGDKSEE 1465

Query: 391  VQDXXXXXXXXXXXGIETAGGVMTPLIKRNXXXXXXXXXXXXXYSDNQSSVLVQVYEGER 450
            VQD           GIETAGGVMT LIKRN             YSDNQ  VL+QVYEGER
Sbjct: 1464 VQDLLLLDVAPLSMGIETAGGVMTALIKRNTTIPTKQTQTFTTYSDNQPGVLIQVYEGER 1285

Query: 451  AMTKDNNLLGKFDLTGIPPAPRGVPQIEVTFDIDANGILNVTAADKSTGKENKITITNDK 510
            AMT+DNNLLGKF+LTGIPPAPRGVPQIEVTFDIDANGILNV+AADKSTGKENKITITNDK
Sbjct: 1284 AMTRDNNLLGKFELTGIPPAPRGVPQIEVTFDIDANGILNVSAADKSTGKENKITITNDK 1105

Query: 511  GRLSKDDIDRMVQEAERYKS 530
            GRLSK++I+RMV +AE+ ++
Sbjct: 1104 GRLSKEEIERMVNDAEKSRT 1045

 Score =  116 bits (290), Expect(2) = e-104,   Method: Compositional matrix adjust.
 Identities = 51/79 (64%), Positives = 69/79 (87%)
 Frame = -3

Query: 537  DRVAAKNAVESYTYNIKQTVEDEKLRGKISEQDKNKILDKCQEVINWLDRNQMAEKDEYE 596
            +R+++KN++ESY +++K T+EDEK++ KI E+DK  I+DKC EVI+WLD NQ AEKDEY+
Sbjct: 1027 NRISSKNSLESYAFHMKSTIEDEKIKDKIGEEDKKTIVDKCNEVISWLDANQTAEKDEYD 848

Query: 597  HKQKELERVCNPIISKLYQ 615
             KQKELE+VCNPII+KLYQ
Sbjct: 847  DKQKELEKVCNPIITKLYQ 791
>21024
          Length = 3220

 Score =  218 bits (554), Expect = 7e-57,   Method: Compositional matrix adjust.
 Identities = 127/331 (38%), Positives = 189/331 (57%), Gaps = 10/331 (3%)
 Frame = +1

Query: 264  RRLRTAC------ERAKRTLSSSTQASIEIDSLYEGVD----FYTSITRARFEELNADLF 313
            +R++  C      +++K  LSSS Q  I +  L             ++R++FE L   L 
Sbjct: 988  QRIQWLCRDYVRQQKSKIELSSSLQTDINLPYLTMDASGPKHMNLKLSRSKFESLVESLV 1167

Query: 314  RGTLEPVEKALRDAKLDKGQIQEIVLVGGSTRIPKIQKLLQDFFNGKELNKSINPDEXXX 373
            + T+ P +KAL+DA++ K  I E++LVGG +R+PK+Q  +QD F G+  +KS+NPDE   
Sbjct: 1168 KRTVGPCQKALQDAEVKKSDIGEVILVGGMSRMPKVQSTVQDLF-GRTPSKSVNPDEAVA 1344

Query: 374  XXXXXXXXILIGDKSENVQDXXXXXXXXXXXGIETAGGVMTPLIKRNXXXXXXXXXXXXX 433
                    +L GD    V D           GIET GGV T LI RN             
Sbjct: 1345 IGAAIQGGVLAGD----VTDVLLLDVTPLSLGIETLGGVFTKLINRNTTIPTKKSQVFST 1512

Query: 434  YSDNQSSVLVQVYEGERAMTKDNNLLGKFDLTGIPPAPRGVPQIEVTFDIDANGILNVTA 493
             +D Q+ V ++V++GER M  DN LLG+F L GIPPAPRGVPQ+EVTFDIDANGI+NV+A
Sbjct: 1513 AADGQTQVEIKVHQGEREMANDNKLLGQFTLVGIPPAPRGVPQVEVTFDIDANGIVNVSA 1692

Query: 494  ADKSTGKENKITITNDKGRLSKDDIDRMVQEAERYKSEDEANRDRVAAKNAVESYTYNIK 553
             DK TGKE +I I +  G LSKD+I+ M++ AE +  +D   ++ V   N  +S  ++ +
Sbjct: 1693 RDKGTGKEQQIVIQSSGG-LSKDEIENMIKNAEAHAEDDRRKKELVEVLNQADSIIHDTE 1869

Query: 554  QTVEDEKLRGKISEQDKNKILDKCQEVINWL 584
              +E+   + ++ +++ +K+ +K  EV   L
Sbjct: 1870 SKMEE--FKDQLPQEECDKLREKINEVKQLL 1956

 Score =  185 bits (469), Expect = 6e-47,   Method: Compositional matrix adjust.
 Identities = 117/271 (43%), Positives = 163/271 (60%), Gaps = 2/271 (0%)
 Frame = +3

Query: 4   RGPAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFT-DTERLIGDAAKNQVAM 62
           +G  IGIDLGTT SCV + +  + +++ N +G+RTTPS +AFT D ER+ G  AK Q   
Sbjct: 243 KGHVIGIDLGTTNSCVALMEGKQAKVLENSEGSRTTPSVIAFTKDGERISGMPAKRQAVT 422

Query: 63  NPTNTIFDAKRLIGRKFEDATVQSDMKHWPFRVVSEGGKPKVQVEYKGEMKTFFPEEISS 122
           N  NT+   KRLIGR+FED  VQ DMK+  +++V +       VE +G+M  + P ++ +
Sbjct: 423 NAENTLSATKRLIGRRFEDPEVQKDMKNVSYKIV-KASNGDAWVEAQGKM--YSPSQVGA 593

Query: 123 MVLTKMKEIAEAYLGGKVQSAVITVPAYFNDSQRQATKDAGTITGLNVLRIINEPTAAAI 182
            VL KMKE AE+YLG KV +AV+TVPAYFNDSQRQATKDAG I+GL  +   ++ T +  
Sbjct: 594 FVLMKMKETAESYLGSKVNNAVVTVPAYFNDSQRQATKDAGQISGLKCV-ACDQRTHSCS 770

Query: 183 AYGLDKKGCAGGEKNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGE-DFDNRMV 241
           +  +            LI   G  T  +S  +  + +   + T  +TH   E  FDN MV
Sbjct: 771 SCFMAWTSLKIK**RCLI*AEGRLT-SLSWRSRRECLKSNQPT--ETHSWEERTFDNYMV 941

Query: 242 SHLAEEFKRKHKKDIGPNKRAVRRLRTACER 272
           + LA EFK++   DI  +  AV+RLR A E+
Sbjct: 942 NFLASEFKKEQGLDITKDPMAVQRLREAAEK 1034
>27378
          Length = 410

 Score =  194 bits (492), Expect = 1e-49,   Method: Compositional matrix adjust.
 Identities = 94/124 (75%), Positives = 106/124 (85%)
 Frame = -1

Query: 247 EFKRKHKKDIGPNKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGVDFYTSITRARFE 306
           EFKRK+KKD+  N RA+RRLRTA ERAKRTLSSST+A+IE+D+L+EG DFYT I+RARFE
Sbjct: 410 EFKRKYKKDLRSNPRALRRLRTAAERAKRTLSSSTEATIEVDALFEGHDFYTKISRARFE 231

Query: 307 ELNADLFRGTLEPVEKALRDAKLDKGQIQEIVLVGGSTRIPKIQKLLQDFFNGKELNKSI 366
           EL ADLFR TL PVEKAL DAK+DK  I +IVLVGGSTRIPK+Q LLQ FF GK LN SI
Sbjct: 230 ELCADLFRQTLAPVEKALNDAKMDKQMIHDIVLVGGSTRIPKVQNLLQQFFGGKSLNLSI 51

Query: 367 NPDE 370
           NPDE
Sbjct: 50  NPDE 39
>26390
          Length = 665

 Score =  164 bits (414), Expect = 1e-40,   Method: Compositional matrix adjust.
 Identities = 86/183 (46%), Positives = 112/183 (61%), Gaps = 6/183 (3%)
 Frame = +2

Query: 405 GIETAGGVMTPLIKRNXXXXXXXXXXXXXYSDNQSSVLVQVYEGERAMTKDNNLLGKFDL 464
           GIET GGVMT LI R                DNQ SV +QVYEGER+ TKDN+LLG+FDL
Sbjct: 50  GIETVGGVMTTLIARGTTIPARKAKVFSTAQDNQDSVTIQVYEGERSRTKDNHLLGRFDL 229

Query: 465 TGIPPAPRGVPQIEVTFDIDANGILNVTAADKSTGKENKITITNDKGRLSKDDIDRMVQE 524
           TGIP APRGVPQIEVTF +DANG++ V+A DK TG++N I I      LS +D++RMVQE
Sbjct: 230 TGIPAAPRGVPQIEVTFQVDANGVMQVSAEDKGTGQKNDIIIQQSGSGLSPEDVERMVQE 409

Query: 525 AERYKSEDEANRDRVAAKNAVESYTYNIKQTVED------EKLRGKISEQDKNKILDKCQ 578
           A+ +  ED   R+   ++  +ES  Y  +  ++D       +  G +S+ D    L   Q
Sbjct: 410 AQDFAEEDRKFRELTESRTGLESLAYTAQHQLQDLHKMXASERPGTLSDDD----LHXAQ 577

Query: 579 EVI 581
           EV+
Sbjct: 578 EVV 586
>37715
          Length = 468

 Score =  147 bits (370), Expect = 1e-35,   Method: Compositional matrix adjust.
 Identities = 71/113 (62%), Positives = 85/113 (75%)
 Frame = -2

Query: 93  FRVVSEGGKPKVQVEYKGEMKTFFPEEISSMVLTKMKEIAEAYLGGKVQSAVITVPAYFN 152
            +V+++  KP +Q    G  KTF PEEIS+MVL KM++IAEAYLG K+ +AV+TVPAYFN
Sbjct: 458 LKVINKSNKPHIQALVSGATKTFAPEEISAMVLGKMRDIAEAYLGKKIDNAVVTVPAYFN 279

Query: 153 DSQRQATKDAGTITGLNVLRIINEPTAAAIAYGLDKKGCAGGEKNVLIFDLGG 205
           D+QRQATKDAGTI GLNV+RIINEPTAAAIAYGLDK+    GEK         
Sbjct: 278 DAQRQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKR---DGEKTFWCLTWAA 129

 Score = 81.3 bits (199), Expect = 1e-15,   Method: Composition-based stats.
 Identities = 34/49 (69%), Positives = 44/49 (89%)
 Frame = -1

Query: 196 KNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVSHL 244
           +N+L+FDLGGGTFDVS+LTI++G+FEV +T GDTHLGGEDFD R++ H 
Sbjct: 159 ENILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMDHF 13
>24750
          Length = 552

 Score =  139 bits (350), Expect = 3e-33,   Method: Compositional matrix adjust.
 Identities = 65/71 (91%), Positives = 71/71 (100%)
 Frame = +1

Query: 442 LVQVYEGERAMTKDNNLLGKFDLTGIPPAPRGVPQIEVTFDIDANGILNVTAADKSTGKE 501
           ++QVYEGERAMT+DNNLLGKF+LTGIPPAPRGVPQIEVTFDIDANGILNV+AADKSTGKE
Sbjct: 154 MLQVYEGERAMTRDNNLLGKFELTGIPPAPRGVPQIEVTFDIDANGILNVSAADKSTGKE 333

Query: 502 NKITITNDKGR 512
           NKITITNDKG+
Sbjct: 334 NKITITNDKGQ 366
>06909
          Length = 456

 Score = 99.4 bits (246), Expect(2) = 2e-24,   Method: Compositional matrix adjust.
 Identities = 45/65 (69%), Positives = 56/65 (86%)
 Frame = -3

Query: 551 NIKQTVEDEKLRGKISEQDKNKILDKCQEVINWLDRNQMAEKDEYEHKQKELERVCNPII 610
           ++K T+EDEK++ KIS +DK  ILDKC EVI WLD NQ+AEKDEY+ KQKE+E+VCNPII
Sbjct: 385 HMKSTIEDEKIKDKISTEDKKTILDKCDEVIAWLDANQLAEKDEYDDKQKEIEKVCNPII 206

Query: 611 SKLYQ 615
           +KLYQ
Sbjct: 205 TKLYQ 191

 Score = 31.2 bits (69), Expect(2) = 2e-24,   Method: Composition-based stats.
 Identities = 11/22 (50%), Positives = 18/22 (81%)
 Frame = -1

Query: 527 RYKSEDEANRDRVAAKNAVESY 548
           +YK +DE  + R++AKN++ESY
Sbjct: 456 KYKEDDEKQKSRISAKNSLESY 391
>31218
          Length = 322

 Score = 89.4 bits (220), Expect = 5e-18,   Method: Composition-based stats.
 Identities = 48/100 (48%), Positives = 68/100 (68%)
 Frame = +2

Query: 228 DTHLGGEDFDNRMVSHLAEEFKRKHKKDIGPNKRAVRRLRTACERAKRTLSSSTQASIEI 287
           DTHLGGEDFD R+V +L +  K+K  +D+  + RA+ RLR + E+AKR LSS     +++
Sbjct: 2   DTHLGGEDFDQRLVDYLVKLIKQKTGRDVRHDTRAMSRLRRSAEKAKRALSSQHSTKVDL 181

Query: 288 DSLYEGVDFYTSITRARFEELNADLFRGTLEPVEKALRDA 327
           D +   +   T +TRA+FEELN DLFR TL  V++AL D+
Sbjct: 182 DGVTSDLADLT-LTRAKFEELNTDLFRSTLTTVKRALEDS 298
>09881
          Length = 600

 Score = 86.7 bits (213), Expect = 2e-17,   Method: Composition-based stats.
 Identities = 40/103 (38%), Positives = 63/103 (61%)
 Frame = +3

Query: 7   AIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTN 66
           A G+ LGT  +C+ V++ GK  + AND G+R+TP  VAFT  +  +G +AK  +  N  N
Sbjct: 186 AYGVHLGTCSACLAVYKDGKTSVAANDAGDRSTPCVVAFTACDAEVGASAKQGIVSNVKN 365

Query: 67  TIFDAKRLIGRKFEDATVQSDMKHWPFRVVSEGGKPKVQVEYK 109
           T+ + KR++G  FED   Q  +   P +VV++  +P  +VE+K
Sbjct: 366 TVCNVKRILGLTFEDPVTQEYLASSPVKVVNQKNQPMFEVEFK 494

 Score = 47.8 bits (112), Expect = 1e-05,   Method: Composition-based stats.
 Identities = 25/50 (50%), Positives = 33/50 (66%)
 Frame = +2

Query: 137 GGKVQSAVITVPAYFNDSQRQATKDAGTITGLNVLRIINEPTAAAIAYGL 186
           G  +Q AV+ VP+ F+D QR A   A +  G  VLR+INE +AAA+AY L
Sbjct: 2   GKGIQDAVLAVPSDFSDKQRAAASAAASKAGFKVLRLINECSAAALAYDL 151
>20979
          Length = 976

 Score = 86.3 bits (212), Expect = 3e-17,   Method: Compositional matrix adjust.
 Identities = 48/140 (34%), Positives = 81/140 (57%), Gaps = 2/140 (1%)
 Frame = +1

Query: 233 GEDFDNRMVSHLAEEF--KRKHKKDIGPNKRAVRRLRTACERAKRTLSSSTQASIEIDSL 290
           G +   R+  HLA+ F  ++K    +  N RA+ +L    ER K+ LS+++    +++ L
Sbjct: 70  GVEMTLRLRDHLAKVFNGQKKRSFKLEDNPRAMAKLLKEAERVKKVLSANSDHKAQVEGL 249

Query: 291 YEGVDFYTSITRARFEELNADLFRGTLEPVEKALRDAKLDKGQIQEIVLVGGSTRIPKIQ 350
            EG DF   ++R  + EL  DL     +P+E AL+ +++   +I EI+L+GG +R+P++Q
Sbjct: 250 VEGEDFAAKVSREDYLELIKDLLARVTKPMEDALKVSEITMPEITEIILMGGGSRVPRVQ 429

Query: 351 KLLQDFFNGKELNKSINPDE 370
           + L  F    +L KSIN DE
Sbjct: 430 EELLKFSGKSDLGKSINTDE 489
>12271
          Length = 1762

 Score = 63.9 bits (154), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 30/76 (39%), Positives = 47/76 (61%)
 Frame = +2

Query: 295 DFYTSITRARFEELNADLFRGTLEPVEKALRDAKLDKGQIQEIVLVGGSTRIPKIQKLLQ 354
           DF   +TR ++  L  DL      PV++ L  +++   +I EI+L+GG +R+PKI ++L 
Sbjct: 41  DFSCKVTRDKYLHLIQDLLDRVTLPVQQVLTASQITWAEITEIILMGGGSRLPKIHEILL 220

Query: 355 DFFNGKELNKSINPDE 370
           D+   KEL KS+N DE
Sbjct: 221 DYSGKKELGKSLNTDE 268

 Score = 34.3 bits (77), Expect = 0.17,   Method: Compositional matrix adjust.
 Identities = 24/98 (24%), Positives = 44/98 (44%), Gaps = 3/98 (3%)
 Frame = +1

Query: 490  NVTAADKSTGKENKITIT---NDKGRLSKDDIDRMVQEAERYKSEDEANRDRVAAKNAVE 546
            N  AA    G   K+ +T    D   LSKD + +  +    ++  DE       A+N VE
Sbjct: 937  NKKAASAGKGFNEKLKVTVKVKDMAELSKDQVKQSKKRLTDWRKRDEEKAAVQKARNEVE 1116

Query: 547  SYTYNIKQTVEDEKLRGKISEQDKNKILDKCQEVINWL 584
            S+    +  + +E      +++++  ILD+  +  +WL
Sbjct: 1117 SFIITAQDKMSEETYLASSTDEERAXILDQLSQASDWL 1230
>13684
          Length = 438

 Score = 55.5 bits (132), Expect = 6e-08,   Method: Composition-based stats.
 Identities = 24/57 (42%), Positives = 36/57 (63%)
 Frame = -3

Query: 7   AIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMN 63
           A G+ LGT  +C+ V++ GK  + AND G+R+TP  VAFT  +  +G +AK  +  N
Sbjct: 172 AYGVHLGTCSACLAVYKDGKTSVAANDAGDRSTPCVVAFTACDAEVGASAKQGIVSN 2
>03996
          Length = 1105

 Score = 52.0 bits (123), Expect = 7e-07,   Method: Compositional matrix adjust.
 Identities = 26/64 (40%), Positives = 41/64 (64%)
 Frame = -2

Query: 307  ELNADLFRGTLEPVEKALRDAKLDKGQIQEIVLVGGSTRIPKIQKLLQDFFNGKELNKSI 366
            EL  DL     +P+E AL+ +++   +I EI+L+GG +R+P++Q+ L  F    +L KSI
Sbjct: 1056 ELIKDLLARVTKPMEDALKVSEITMPEITEIILMGGGSRVPRVQEELLKFSGKSDLGKSI 877

Query: 367  NPDE 370
            N DE
Sbjct: 876  NTDE 865
>34036
          Length = 363

 Score = 50.1 bits (118), Expect = 3e-06,   Method: Composition-based stats.
 Identities = 20/25 (80%), Positives = 24/25 (96%)
 Frame = +2

Query: 591 EKDEYEHKQKELERVCNPIISKLYQ 615
           EKDEY+ KQKE+E+VCNPII+KLYQ
Sbjct: 2   EKDEYDDKQKEIEKVCNPIITKLYQ 76
>13300
          Length = 453

 Score = 49.3 bits (116), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 35/149 (23%), Positives = 73/149 (48%), Gaps = 15/149 (10%)
 Frame = +3

Query: 155 QRQATKDAGTITGLNVLRIINEPTAAAIAYGL-DKKGCAGGEKNVLIFDLGGGTFDVSIL 213
           +R+A   A    G+NVL+++ +  A A+ YG+  +K      +  + +D+G  +   +++
Sbjct: 3   ERRAIMTAADXVGINVLQLMTDSAAVALNYGVFRRKNFNTTAQYYMFYDMGATSTVATVV 182

Query: 214 T-----IEDGI-------FEVKSTAGDTHLGGEDFDNRMVSHLAEEFKRKHKKD--IGPN 259
           +     +++G          +K    D  LGG +   R+  HLA+ F  + K+   +  N
Sbjct: 183 SYQVVKVKEGTRVESNPQLTIKGVGFDRTLGGLEMTLRLRDHLAKVFNGQKKRSFKLEDN 362

Query: 260 KRAVRRLRTACERAKRTLSSSTQASIEID 288
            RA+ +L    ER K+ LS+++    +++
Sbjct: 363 PRAMAKLLKEAERVKKVLSANSDHKAQVE 449
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6678365|ref|NP_033417.1| RAN, member RAS oncogene
family [Mus musculus]
         (216 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

01972                                                                 339   e-104
34359                                                                 224   5e-91
08428                                                                  92   1e-19
14456                                                                  89   1e-18
05468                                                                  89   2e-18
17511                                                                  87   6e-18
33374                                                                  72   1e-17
34468                                                                  85   2e-17
13901                                                                  83   7e-17
07465                                                                  79   1e-15
11728                                                                  79   1e-15
26083                                                                  79   2e-15
11257                                                                  73   1e-13
19006                                                                  72   1e-13
07580                                                                  62   1e-12
30760                                                                  66   9e-12
33794                                                                  64   6e-11
13745                                                                  64   6e-11
12339                                                                  62   2e-10
19656                                                                  59   2e-09
33380                                                                  58   4e-09
35581                                                                  55   3e-08
01398                                                                  52   1e-07
32723                                                                  52   1e-07
26536                                                                  52   2e-07
13750                                                                  52   2e-07
31291                                                                  52   3e-07
27191                                                                  51   4e-07
00858                                                                  50   5e-07
19046                                                                  50   9e-07
29380                                                                  47   5e-06
24619                                                                  47   6e-06
00552                                                                  42   2e-04
36482                                                                  41   3e-04
08153                                                                  39   0.001
14775                                                                  38   0.003
09204                                                                  37   0.005
09827                                                                  37   0.008
33605                                                                  35   0.019
10708                                                                  35   0.019
20290                                                                  33   0.10 
10862                                                                  32   0.16 
13795                                                                  30   0.97 
18248                                                                  29   1.5  
33029                                                                  29   1.7  
11357                                                                  27   4.6  
02253                                                                  27   6.0  
>01972
          Length = 2359

 Score =  339 bits (869), Expect(2) = e-104,   Method: Compositional matrix adjust.
 Identities = 157/180 (87%), Positives = 169/180 (93%)
 Frame = +3

Query: 37  KKYVATLGVEVHPLVFHTNRGPIKFNVWDTAGQEKFGGLRDGYYIQAQCAIIMFDVTSRV 96
           KKYVATLGVEVHPL+FHT+RG +KFNVWDTAGQEKFGGLRDGYYIQ QCA+IMFDVTSRV
Sbjct: 381 KKYVATLGVEVHPLLFHTSRGKLKFNVWDTAGQEKFGGLRDGYYIQGQCAVIMFDVTSRV 560

Query: 97  TYKNVPNWHRDLVRVCENIPIVLCGNKVDIKDRKVKAKSIVFHRKKNLQYYDISAKSNYN 156
           TYKNVPNWHRDLVRVCENIPIVLCGNKVDIKDRKVKAK+IVFHRKKNLQYYDISAKSNYN
Sbjct: 561 TYKNVPNWHRDLVRVCENIPIVLCGNKVDIKDRKVKAKAIVFHRKKNLQYYDISAKSNYN 740

Query: 157 FEKPFLWLARKLIGDPNLEFVAMPALAPPEVVMDPALAAQYEHDLEVAQTTALPDEDDDL 216
           FEKPFLWLARKL+GDPNLEFV MPAL PPEV MD  LA +YE +L+VAQ  ALPD+D+D+
Sbjct: 741 FEKPFLWLARKLVGDPNLEFVEMPALLPPEVAMDAVLAKKYEEELKVAQEVALPDDDEDI 920

 Score = 55.5 bits (132), Expect(2) = e-104,   Method: Compositional matrix adjust.
 Identities = 26/32 (81%), Positives = 28/32 (87%)
 Frame = +1

Query: 6   EPQVQFKLVLVGDGGTGKTTFVKRHLTGEFEK 37
           E +  FKLVLVGDGG GKTTFVKRH+TGEFEK
Sbjct: 289 EQEPTFKLVLVGDGGVGKTTFVKRHVTGEFEK 384
>34359
          Length = 1042

 Score =  224 bits (572), Expect(2) = 5e-91,   Method: Compositional matrix adjust.
 Identities = 109/136 (80%), Positives = 116/136 (85%)
 Frame = +3

Query: 10  QFKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIKFNVWDTAGQ 69
            FKLVLVG         VKRH+TG   KKYVATLGVEVHPL F+T+RG ++FNVWDTAGQ
Sbjct: 51  NFKLVLVGGRWEWANNIVKRHVTGS*-KKYVATLGVEVHPLQFNTSRGLLRFNVWDTAGQ 227

Query: 70  EKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLVRVCENIPIVLCGNKVDIKDR 129
           EKFGGLRDGYYIQ  CAIIMFDVTSRVTYKNVPNWHRDLVRVCENIPIVLCGNKVDIKDR
Sbjct: 228 EKFGGLRDGYYIQGTCAIIMFDVTSRVTYKNVPNWHRDLVRVCENIPIVLCGNKVDIKDR 407

Query: 130 KVKAKSIVFHRKKNLQ 145
           KVKAK+IVFHRK+   
Sbjct: 408 KVKAKAIVFHRKRTCS 455

 Score =  127 bits (318), Expect(2) = 5e-91,   Method: Compositional matrix adjust.
 Identities = 58/79 (73%), Positives = 68/79 (86%)
 Frame = +2

Query: 138 FHRKKNLQYYDISAKSNYNFEKPFLWLARKLIGDPNLEFVAMPALAPPEVVMDPALAAQY 197
             ++KNLQYYDISAKSNYNFEKPFLWLARKL+GDPNL FV MPAL PPEV MDP +A +Y
Sbjct: 431 LSQEKNLQYYDISAKSNYNFEKPFLWLARKLVGDPNLXFVEMPALLPPEVAMDPNMAKRY 610

Query: 198 EHDLEVAQTTALPDEDDDL 216
           E +L+VAQ  ALPD+D+D+
Sbjct: 611 EDELKVAQEVALPDDDEDI 667
>08428
          Length = 1109

 Score = 92.4 bits (228), Expect = 1e-19,   Method: Compositional matrix adjust.
 Identities = 53/160 (33%), Positives = 87/160 (54%), Gaps = 3/160 (1%)
 Frame = -3

Query: 12   KLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIKFNVWDTAGQEK 71
            K+ L+GD G GK++ V R +TG +     +T+G          +    +F +WDTAGQEK
Sbjct: 1065 KVCLLGDSGVGKSSIVLRFVTGSYRPSQESTIGASFMSKSLVVDGAGYRFQIWDTAGQEK 886

Query: 72   FGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLVRVC-ENIPIVLCGNKVDIKDRK 130
            F  L   YY  A  A+I++DVT   T+K+V +W ++L      NI + + GNK D+++ +
Sbjct: 885  FRALAPMYYRGAAAAVIVYDVTRPRTFKSVKSWIQELRSFGPPNIVLAIAGNKCDLEELR 706

Query: 131  --VKAKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKL 168
              V+  +  +    +  + + SA +  N E+ F  LAR+L
Sbjct: 705  EVVEKDAQEYASSISAIFGETSAMTAVNVEEMFTELARQL 586
>14456
          Length = 1867

 Score = 89.4 bits (220), Expect = 1e-18,   Method: Compositional matrix adjust.
 Identities = 49/158 (31%), Positives = 83/158 (52%), Gaps = 8/158 (5%)
 Frame = -1

Query: 19   GGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIKFNVWDTAGQEKFGGLRDG 78
            GG GK++ + R ++ +F+ +   T+GVE        +       +WDTAGQE+F  LR  
Sbjct: 1114 GGVGKSSLMNRFVSNKFDAQSFHTIGVEFLNKDVVVDDETYTMQIWDTAGQERFKSLRTP 935

Query: 79   YYIQAQCAIIMFDVTSRVTYKNVPNWHRDLVRVCE-----NIPIVLCGNKVDIKDRKV-- 131
            +Y  A C ++ F V S  +++N+  W ++ +   +       P V+ GNK+D++ R+V  
Sbjct: 934  FYRGADCCLLTFSVDSMQSFRNLSMWRKEFLYYADIQDGVTFPFVVLGNKIDVEGRQVTN 755

Query: 132  -KAKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKL 168
             +A+S       N  Y++ SAK   N EK FL   ++L
Sbjct: 754  EEARSWC-TANSNAPYFETSAKDATNVEKAFLAAVQRL 644
>05468
          Length = 1558

 Score = 89.0 bits (219), Expect = 2e-18,   Method: Compositional matrix adjust.
 Identities = 57/169 (33%), Positives = 96/169 (56%), Gaps = 10/169 (5%)
 Frame = -3

Query: 11   FKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGP-IKFNVWDTAGQ 69
            +K++++G+ GTGKT+ +KR++   F + Y AT+GV+    V + +    I+  +WD AGQ
Sbjct: 1538 YKILVIGELGTGKTSIIKRYVHQFFSQHYRATIGVDFALKVLNWDADTLIRLQLWDIAGQ 1359

Query: 70   EKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDL---VRVCEN--IPIVLCGNKV 124
            E+FG +   YY +A  A ++FDVT   T+  V  W  DL   V++ +   +P VL  NK 
Sbjct: 1358 ERFGNMTRVYYKEAVGAFVVFDVTRASTFDAVTKWKNDLDSKVQLADGSPVPCVLLANKC 1179

Query: 125  D-IKDRKVKAKSIV--FHRKKN-LQYYDISAKSNYNFEKPFLWLARKLI 169
            D  K+  V   S +  F  +K  + +Y+ SAK N N ++   +L  +++
Sbjct: 1178 DQAKEGLVNNTSQMDEFCSEKGFIGWYETSAKENINIDEAARFLVTRIL 1032
>17511
          Length = 483

 Score = 86.7 bits (213), Expect = 6e-18,   Method: Compositional matrix adjust.
 Identities = 40/124 (32%), Positives = 72/124 (58%), Gaps = 5/124 (4%)
 Frame = -3

Query: 8   QVQFKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIKFNVWDTA 67
           +V  K++++GD G GKT+ + +++  +F  +Y AT+G +        +   +   +WDTA
Sbjct: 373 KVLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQIWDTA 194

Query: 68  GQEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLV-----RVCENIPIVLCGN 122
           GQE+F  L   +Y  A C +++FDVT   T++++ +W  + +     R  EN P V+ GN
Sbjct: 193 GQERFQSLGVAFYRGADCCVLVFDVTMPNTFRSLDSWRDEFLIQASPRDPENFPFVVIGN 14

Query: 123 KVDI 126
           K+D+
Sbjct: 13  KIDL 2
>33374
          Length = 489

 Score = 71.6 bits (174), Expect(2) = 1e-17,   Method: Compositional matrix adjust.
 Identities = 35/101 (34%), Positives = 61/101 (60%), Gaps = 3/101 (2%)
 Frame = +1

Query: 59  IKFNVWDTAGQEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLVRVCE-NIPI 117
           +KF +WDTAGQE++  L   YY  AQ AI+++D+T++ T+     W ++L R    NI I
Sbjct: 175 VKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNQDTFGRAKTWVKELQRQASPNIVI 354

Query: 118 VLCGNKVDIKDRKVK--AKSIVFHRKKNLQYYDISAKSNYN 156
            L GNK D+ ++++    ++  +  + +L + + SAK+  N
Sbjct: 355 ALAGNKADLANKRMVEFEEAQAYAEENSLLFMETSAKTAMN 477

 Score = 34.3 bits (77), Expect(2) = 1e-17,   Method: Compositional matrix adjust.
 Identities = 18/43 (41%), Positives = 28/43 (65%)
 Frame = +2

Query: 2  AAQGEPQVQFKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLG 44
          A QG+   QFKLVL+G+   GK++ V R + G+F +   +T+G
Sbjct: 8  ATQGKI-CQFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIG 133
>34468
          Length = 1502

 Score = 84.7 bits (208), Expect = 2e-17,   Method: Compositional matrix adjust.
 Identities = 54/193 (27%), Positives = 94/193 (48%), Gaps = 11/193 (5%)
 Frame = +1

Query: 6   EPQVQ---FKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIKFN 62
           E Q Q   FK++++GD   GKT    R   G+F  K  AT+GV+        +   +K  
Sbjct: 472 EKQTQRRIFKIIVIGDSNVGKTCLTYRFCLGKFPDKTEATIGVDFREKSIQVDSEHLKLQ 651

Query: 63  VWDTAGQEKF-GGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLVR--VCENIPIVL 119
           +WDTAGQE+F   +   YY      + ++D+T   +++N+P W  +  R  + + IP +L
Sbjct: 652 LWDTAGQERFRKSMVQHYYRNVHAVVFVYDMTKMSSFENMPAWIEECDRHNLTKYIPRIL 831

Query: 120 CGNKVDIKDRKVKAKSIV--FHRKKNLQYYDISAKSNY---NFEKPFLWLARKLIGDPNL 174
            GNK D+ +R     ++   F    N+  ++ SAK +    + +  F+ +A KL     +
Sbjct: 832 VGNKCDVVERIAVNTNLAQKFADAHNMPLFETSAKDDEKANHVDAIFMTVAHKLKXSKPM 1011

Query: 175 EFVAMPALAPPEV 187
               +  + P +V
Sbjct: 1012MPAHLSEMVPGDV 1050
>13901
          Length = 962

 Score = 83.2 bits (204), Expect = 7e-17,   Method: Compositional matrix adjust.
 Identities = 38/100 (38%), Positives = 60/100 (60%), Gaps = 1/100 (1%)
 Frame = -3

Query: 6   EPQVQFKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFH-TNRGPIKFNVW 64
             +V FK++++GD   GKT+FV+R++   F + Y  T+GV+    V   +++  IK  +W
Sbjct: 300 SEEVLFKVIIIGDPTVGKTSFVQRYVNDSFRRDYKMTIGVDFALKVIRWSDKCNIKLQLW 121

Query: 65  DTAGQEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNW 104
           D AGQE+F  +   YY  A   I+MFD+T + TY+N   W
Sbjct: 120 DIAGQERFTSMTRVYYKDAHACIVMFDLTQKNTYQNAIRW 1
>07465
          Length = 1103

 Score = 79.0 bits (193), Expect = 1e-15,   Method: Compositional matrix adjust.
 Identities = 44/154 (28%), Positives = 78/154 (50%), Gaps = 4/154 (2%)
 Frame = +3

Query: 24  TTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIKFNVWDTAGQEKFGGLRDGYYIQA 83
           ++ ++R+  G F K Y  T+GV+            ++  +WDTAGQE+F  +   YY  A
Sbjct: 240 SSMIQRYCKGIFTKDYKKTIGVDFLERQIEVGGEDVRLMLWDTAGQEEFDAITKAYYRGA 419

Query: 84  QCAIIMFDVTSRVTYKNVPNWHRDLVRVCENIPIVLCGNKVDIKD----RKVKAKSIVFH 139
           Q  ++ F    R +++ +  W R +      I +V+  NK+D+ D    R  +A+++   
Sbjct: 420 QACVLAFSTVDRDSFEALETWKRKVEDEVGEIGMVIVQNKIDLIDDAVVRPEEAENLA-- 593

Query: 140 RKKNLQYYDISAKSNYNFEKPFLWLARKLIGDPN 173
           +K  L++Y  S K N N ++ F +LA K +   N
Sbjct: 594 KKLRLRFYRTSVKENMNVDEVFRYLADKYLHQLN 695
>11728
          Length = 635

 Score = 79.0 bits (193), Expect = 1e-15,   Method: Compositional matrix adjust.
 Identities = 41/121 (33%), Positives = 65/121 (53%), Gaps = 1/121 (0%)
 Frame = -1

Query: 11  FKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIKFNVWDTAGQE 70
            K V+VGDG  GKT  +  + T  F  +Y+ T+  + +      +  PI   +WDTAGQE
Sbjct: 488 IKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTV-FDNYSANVMVDSKPINLGLWDTAGQE 312

Query: 71  KFGGLRDGYYIQAQCAIIMFDVTSRVTYKNV-PNWHRDLVRVCENIPIVLCGNKVDIKDR 129
            +  LR   Y Q    +I F + S  +++NV   W+ ++   C N PI+L G K+D+++ 
Sbjct: 311 DYDRLRPLSYPQTDVFLICFSLISPASFENVKAKWYPEVSHHCPNTPIILVGTKLDLRED 132

Query: 130 K 130
           K
Sbjct: 131 K 129
>26083
          Length = 432

 Score = 78.6 bits (192), Expect = 2e-15,   Method: Compositional matrix adjust.
 Identities = 37/120 (30%), Positives = 64/120 (53%), Gaps = 1/120 (0%)
 Frame = +1

Query: 5   GEPQVQFKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIKFNVW 64
           G P  +FKLV +G+   GKT+ + R +   F+  Y AT+G++      +     I+  +W
Sbjct: 61  GNPLRKFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTIRLQLW 240

Query: 65  DTAGQEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDL-VRVCENIPIVLCGNK 123
           DTAGQE+F  L   Y   +  A++++D+T+  ++     W  D+      ++ I+L GNK
Sbjct: 241 DTAGQERFRSLIPSYIRDSSVAVVVYDITNANSFHQTSKWIDDVRTERGSDVIIMLVGNK 420
>11257
          Length = 1102

 Score = 72.8 bits (177), Expect = 1e-13,   Method: Compositional matrix adjust.
 Identities = 35/113 (30%), Positives = 64/113 (56%), Gaps = 7/113 (6%)
 Frame = -2

Query: 63   VWDTAGQEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLVRVCE-----NIPI 117
            +WDTAGQE++  LR  +Y    C ++ F V +  + +++ +W+ + V   +     + P 
Sbjct: 1014 IWDTAGQERYKSLRTPFYRGTDCCLLTFSVDNLKSLQSLSDWYDEFVNYADIQDSASFPF 835

Query: 118  VLCGNKVDIKDRKVKAKSIV--FHRKKNLQYYDISAKSNYNFEKPFLWLARKL 168
            V+ GNK DI++R+V ++          NL Y++ SAK + N ++ FL + R+L
Sbjct: 834  VIIGNKADIEEREVSSEDAYNWCRTHGNLPYFETSAKDSLNVQQAFLAVVRRL 676
>19006
          Length = 568

 Score = 72.4 bits (176), Expect = 1e-13,   Method: Compositional matrix adjust.
 Identities = 39/118 (33%), Positives = 63/118 (53%), Gaps = 1/118 (0%)
 Frame = -2

Query: 12  KLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIKFNVWDTAGQEK 71
           KLV+VGDG  GKT  +      +F + YV T+  E +      +   ++  +WDTAGQE 
Sbjct: 432 KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTV-FENYVADIEVDSKQVELALWDTAGQED 256

Query: 72  FGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPN-WHRDLVRVCENIPIVLCGNKVDIKD 128
           +  LR   Y      ++ F + S  + +N+P  W  ++   C N+PI+L GNK D+++
Sbjct: 255 YDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVRHFCPNVPIILVGNKKDLRN 82
>07580
          Length = 921

 Score = 62.0 bits (149), Expect(2) = 1e-12,   Method: Compositional matrix adjust.
 Identities = 31/112 (27%), Positives = 62/112 (55%), Gaps = 4/112 (3%)
 Frame = +3

Query: 61  FNVWDTAGQEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLVRV--CENIPIV 118
             + DTAG E+F  +RD Y    Q  ++ + +T++ T+ ++      ++RV   +++P++
Sbjct: 210 LEILDTAGTEQFTAMRDLYMKNGQGFLLAYSITAQSTFNDLQELREQILRVKDTDDVPML 389

Query: 119 LCGNKVDIKDRKV--KAKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKL 168
           L GNK D++D +V  K +     R  +  + + SAK+  N  + F+ L R++
Sbjct: 390 LVGNKCDLEDERVVGKDQGQGLARSFSCAFLETSAKARINVNEIFMDLVRQI 545

 Score = 27.3 bits (59), Expect(2) = 1e-12,   Method: Compositional matrix adjust.
 Identities = 11/30 (36%), Positives = 19/30 (63%)
 Frame = +2

Query: 6  EPQVQFKLVLVGDGGTGKTTFVKRHLTGEF 35
          E   ++KLV++G GG GK+    + + G+F
Sbjct: 47 ETMREYKLVVLGSGGVGKSALTVQFVQGDF 136
>30760
          Length = 596

 Score = 66.2 bits (160), Expect = 9e-12,   Method: Compositional matrix adjust.
 Identities = 44/162 (27%), Positives = 78/162 (48%), Gaps = 8/162 (4%)
 Frame = -1

Query: 12  KLVLVGDGGTGKTTFVK--RHLTGEFEKKYVATLGVEVHPLVFHT--NRGPIKFNVWDTA 67
           K ++ GD G GK++  +     +  F K Y  T GVEV   + +   +R  ++  ++D+A
Sbjct: 524 KCIVTGDSGVGKSSICQVFHSDSAHFPKNYSMTTGVEVLVKLVNIPDSRDQVELYLFDSA 345

Query: 68  GQEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLVRVCEN--IPIVLCGNKVD 125
           G+E F      ++ Q    ++++DVT   ++     W   +     N  IP VL  NK D
Sbjct: 344 GKEIFSENVTKFWDQPSVVMVVYDVTDETSFSGCVRWLERVRAAKPNTVIPGVLVANKTD 165

Query: 126 IKDRK--VKAKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLA 165
           + +R+   + +     +   L+Y++ SAK   N + PF  LA
Sbjct: 164 LDERRRVSRKEGKDLAQSHGLEYFECSAKEMQNTDTPFFCLA 39
>33794
          Length = 779

 Score = 63.5 bits (153), Expect = 6e-11,   Method: Compositional matrix adjust.
 Identities = 33/121 (27%), Positives = 65/121 (53%), Gaps = 2/121 (1%)
 Frame = -1

Query: 59  IKFNVWDTAGQEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLVRVCENIPIV 118
           +K  +WDT+GQ +F  +   Y   AQ  I+++D+T++ ++  +  W +++      IP V
Sbjct: 650 VKLQIWDTSGQGRFCTIIRSYSRGAQGIILVYDITNKWSFDGIDRWLKEVEEHAPGIPKV 471

Query: 119 LCGNKVDIK-DRKVKAKSI-VFHRKKNLQYYDISAKSNYNFEKPFLWLARKLIGDPNLEF 176
           L GN++ +   R+V AK    +  + N+  ++IS   ++N  + F  LAR  +    +E 
Sbjct: 470 LVGNRLHLAYKRQVAAKQAETYASRNNMSCFEISPLCDFNIRESFCELARMALHRNGMEH 291

Query: 177 V 177
           +
Sbjct: 290 I 288
>13745
          Length = 1045

 Score = 63.5 bits (153), Expect = 6e-11,   Method: Compositional matrix adjust.
 Identities = 34/108 (31%), Positives = 59/108 (54%), Gaps = 7/108 (6%)
 Frame = +2

Query: 69  QEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLV-----RVCENIPIVLCGNK 123
           QE+F  L   +Y  A C ++++DVT+  ++KN+ +W  + +     R  E+ P V+ GNK
Sbjct: 2   QERFQSLGVAFYRGADCCVLVYDVTAPNSFKNLDSWRDEFLIQASPRDPEHFPFVVLGNK 181

Query: 124 VDIKDRKVKAKSIV--FHRKKNLQYYDISAKSNYNFEKPFLWLARKLI 169
           VD+ +R+V  +        K ++ YY+ SAK   N E  F  +A+  +
Sbjct: 182 VDLDNRQVSTRRAQQWCQSKNDIPYYETSAKEGINVEMAFQTIAKNAL 325
>12339
          Length = 578

 Score = 61.6 bits (148), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 35/109 (32%), Positives = 58/109 (53%), Gaps = 7/109 (6%)
 Frame = -2

Query: 69  QEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLV-----RVCENIPIVLCGNK 123
           QE+F  L   +Y  A C I+++DVT   T+ ++ +W R+ +     R  E+ P V+ GNK
Sbjct: 577 QERFQSLGVAFYRGADCCILVYDVTEXKTFDSLDSWQREFLNQASPRDPEHFPFVVIGNK 398

Query: 124 VDIKDRKVKAK--SIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKLIG 170
           +D+ +R V AK        K  + Y++ SAK   N E+ F  +A+  + 
Sbjct: 397 IDLDNRVVTAKRGQGWCSTKGGIPYFETSAKEAINVEQAFQTVAKNALA 251
>19656
          Length = 428

 Score = 58.9 bits (141), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 33/102 (32%), Positives = 51/102 (50%), Gaps = 1/102 (0%)
 Frame = +3

Query: 12  KLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIKFNVWDTAGQEK 71
           K V+VGDG  GKT  +  + T  F  +Y+ T+       V    R P+   +WDTAGQE 
Sbjct: 117 KCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGR-PVNLGLWDTAGQED 293

Query: 72  FGGLRDGYYIQAQCAIIMFDVTSRVTYKNV-PNWHRDLVRVC 112
           +  LR   Y Q    ++ F V S  +++N+   W+ ++   C
Sbjct: 294 YDRLRPLSYPQTDVFLLCFSVASPASFENIRAKWYPEVNHHC 419
>33380
          Length = 282

 Score = 57.8 bits (138), Expect = 4e-09,   Method: Compositional matrix adjust.
 Identities = 29/82 (35%), Positives = 48/82 (58%), Gaps = 1/82 (1%)
 Frame = +3

Query: 51  VFHTNRGPIKFNVWDTAGQEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDL-V 109
           VF  ++  +K  +WDTAGQE++  +   YY  A   I+M+DVT+  ++  V +W   +  
Sbjct: 39  VFRQDK-RVKLQIWDTAGQERYRTITTAYYRGAMGFILMYDVTNEESFNAVQDWCTQIKT 215

Query: 110 RVCENIPIVLCGNKVDIKDRKV 131
              +N  +VL GNK D++D +V
Sbjct: 216 YSWDNAQVVLVGNKCDLEDERV 281
>35581
          Length = 364

 Score = 54.7 bits (130), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 28/88 (31%), Positives = 43/88 (48%), Gaps = 1/88 (1%)
 Frame = +2

Query: 5   GEPQVQFKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPI-KFNV 63
           G   + FK VL+GD G GKT  + R  T +F    + +L             G +   ++
Sbjct: 29  GNDTLYFKCVLLGDAGVGKTCLLNRLATDKFLDSPLTSLTTASLLTTVTLTSGVMASVDL 208

Query: 64  WDTAGQEKFGGLRDGYYIQAQCAIIMFD 91
           WDTAGQE++  L   YY   +  +I++D
Sbjct: 209 WDTAGQERYRSLTSSYYRDTKAVLIVYD 292
>01398
          Length = 1421

 Score = 52.4 bits (124), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 34/103 (33%), Positives = 59/103 (57%), Gaps = 5/103 (4%)
 Frame = -2

Query: 69   QEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWH---RDLVRVCENIPIVLCGNKVD 125
            QE+F  +   YY  +   II++D+T R T++N+  W+   R+ +   + I +VL G+K D
Sbjct: 1420 QERFRSITRSYYRNSVGVIIVYDITKRSTFENLKQWYEEARNHIEPHKAIFLVL-GHKSD 1244

Query: 126  IKD-RKVKAKS-IVFHRKKNLQYYDISAKSNYNFEKPFLWLAR 166
             +D R+V A+    F     L++++ SAKS +N E  F  +A+
Sbjct: 1243 REDARQVTAREGRRFAEMHGLKFFETSAKSGHNIEDVFAQIAK 1115
>32723
          Length = 384

 Score = 52.4 bits (124), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 31/108 (28%), Positives = 53/108 (49%), Gaps = 3/108 (2%)
 Frame = +2

Query: 69  QEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNW-HRDLVRVCENIPIVLCGNKVDIK 127
           QE+F  +   YY  A   I+++DV S+ +Y+++P W H   +     +   L GNK+D  
Sbjct: 2   QERFRSITQSYYRSANALILVYDVCSQQSYESLPQWIHEIELYAGTKVLAFLVGNKIDQT 181

Query: 128 DRKVKAKSI--VFHRKKNLQYYDISAKSNYNFEKPFLWLARKLIGDPN 173
           D++     I   F  +  +++ + SAK   N EK F  +A +L     
Sbjct: 182 DKREIPTHIGKEFAERYEMRFLETSAKEADNVEKLFSTIAYQLTAQAQ 325
>26536
          Length = 829

 Score = 52.4 bits (124), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 33/114 (28%), Positives = 56/114 (49%), Gaps = 4/114 (3%)
 Frame = +2

Query: 59  IKFNVWDTAGQEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLVRVCENIPI- 117
           + +   DTAGQE++  +R+ Y       I+++ VT   +++      R L R  +   I 
Sbjct: 128 VSWTFLDTAGQEEYSSMREHYTRSGDGFIVVYSVTDVTSFQEAEAVFRWLTRFQDETSIH 307

Query: 118 -VLCGNKVDI-KDRKVK-AKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKL 168
            VLCGNK D+  DRKV   +      +  + Y++ SAK+  N  + +  L R +
Sbjct: 308 AVLCGNKTDLTSDRKVTPEEGRKMADRLGMLYFETSAKTGDNVSQVYHGLLRSI 469
>13750
          Length = 503

 Score = 51.6 bits (122), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 34/148 (22%), Positives = 74/148 (50%), Gaps = 9/148 (6%)
 Frame = -2

Query: 23  KTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGP---IKFNVWDTAGQEKFGGLRDGY 79
           KT  ++R+  G F  + + T+ V      F+ +R     +++ +WDT G E +  L   +
Sbjct: 502 KTCLLRRYQKGFFMDRTMPTIAVLCSE--FNESRTDPLNVRYTLWDTGGAETYRSLWVSH 329

Query: 80  YIQAQCAIIMFDVTSRVTYKNVPN-WHRDLVRVCENIP---IVLCGNKVDIKDRKVKA-- 133
           +  AQ A++++DVT   ++      W + L++   NIP   ++  G+K D+++ +V +  
Sbjct: 328 FRGAQVALLVYDVTCEWSFLTATTVWRKALMK---NIPEAQVIFVGSKTDLEENRVISTE 158

Query: 134 KSIVFHRKKNLQYYDISAKSNYNFEKPF 161
           +   F  +    +++ S+ +  N +  F
Sbjct: 157 RGQAFATQCGYTFFETSSVTGKNVDAVF 74
>31291
          Length = 446

 Score = 51.6 bits (122), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 31/117 (26%), Positives = 54/117 (46%), Gaps = 16/117 (13%)
 Frame = -1

Query: 61  FNVWDTAGQEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVP-NWHRDLVRVCENIPIVL 119
             +WDTAGQE +  LR   Y      ++ F + S  + KNV   W+ ++     ++PIVL
Sbjct: 446 LQLWDTAGQEDYDRLRPLAYPNTDVFMLXFSLMSEASMKNVKVKWYPEIRHHDPHVPIVL 267

Query: 120 CGNKVDIKDRKVKAKSIVFHRK---------------KNLQYYDISAKSNYNFEKPF 161
            G K+D++  K   + +   R+               K  +Y++ S+K+  N +  F
Sbjct: 266 VGTKLDLRQDKEAVRKLRSSRQDPVSSNQGNDLAKAIKAKRYFECSSKTQENLKTAF 96
>27191
          Length = 443

 Score = 50.8 bits (120), Expect = 4e-07,   Method: Compositional matrix adjust.
 Identities = 26/103 (25%), Positives = 55/103 (53%), Gaps = 1/103 (0%)
 Frame = +1

Query: 23  KTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIKFNVWDTAGQEKFGGLRDGYYIQ 82
           KT  +K     +F + Y  T+GV+    +   N   ++ ++WD +G  ++  +R+  Y  
Sbjct: 1   KTCLIKHFCESKFNQGYQPTVGVDYGFKIQTVNGVDMRVHMWDLSGSNEYLDVRNELYTG 180

Query: 83  AQCAIIMFDVTSRVTYKNVPNWHRDLVRVCENIPI-VLCGNKV 124
           +    I+FDV++  +++ + +W R++ R     P+ V+ GN+V
Sbjct: 181 SDAIFIVFDVSNTPSFEALDSWLREINRFATGSPLNVIVGNRV 309
>00858
          Length = 1658

 Score = 50.4 bits (119), Expect = 5e-07,   Method: Compositional matrix adjust.
 Identities = 30/115 (26%), Positives = 60/115 (52%), Gaps = 7/115 (6%)
 Frame = -2

Query: 61   FNVWDTAGQEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLVRV--CENIPIV 118
             ++ DTAGQE+   +RD      +  + +F V +  +++++  +   + RV   + +P+V
Sbjct: 1441 LDILDTAGQEEXSAMRDQCMRTGEGFLCVFAVXNLKSFEDINQYREQIKRVKDADEVPMV 1262

Query: 119  LCGNKVD-----IKDRKVKAKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKL 168
            L GNKVD     ++ R+ K  + ++H    + Y + SAK+    +  F  L R++
Sbjct: 1261 LVGNKVDLPIRNVEQRQGKHMAELYH----IPYVETSAKTRQGVDDAFYTLVREI 1109
>19046
          Length = 445

 Score = 49.7 bits (117), Expect = 9e-07,   Method: Compositional matrix adjust.
 Identities = 27/88 (30%), Positives = 51/88 (57%), Gaps = 4/88 (4%)
 Frame = -2

Query: 69  QEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLVRV--CENIPIVLCGNKVD- 125
           QE+F  +R+ Y  +    +++F VT   +++N+ N+H  ++RV   ++ P++LC NKVD 
Sbjct: 444 QEEFSAMREQYMRKGDGFLLVFSVTDFRSFENMANFHTQILRVKDRDSYPMILCANKVDL 265

Query: 126 IKDRKVKAKSIV-FHRKKNLQYYDISAK 152
           +  RKV  + +     +  + Y + SAK
Sbjct: 264 VHQRKVSEEQVRDLATRLRIPYIETSAK 181
>29380
          Length = 853

 Score = 47.4 bits (111), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 32/93 (34%), Positives = 52/93 (55%), Gaps = 6/93 (6%)
 Frame = -2

Query: 83  AQCAIIMFDVTSRVTYKNVPNWHRDLVRV-CENIPIVLCGNKVDI--KDRKVK---AKSI 136
           A  AII++DV    T+     W ++L +   E++ I+L GNKVD+  + R V    A+S 
Sbjct: 852 ASAAIIVYDVNIADTFSRALAWVKELRQQNTESVLIILAGNKVDLATQHRAVSFEDAQS- 676

Query: 137 VFHRKKNLQYYDISAKSNYNFEKPFLWLARKLI 169
            F R+  L + ++SAK+     + F+ LA +LI
Sbjct: 675 -FARENGLLFAEVSAKTGMAVNEIFMTLANQLI 580
>24619
          Length = 509

 Score = 47.0 bits (110), Expect = 6e-06,   Method: Compositional matrix adjust.
 Identities = 30/109 (27%), Positives = 56/109 (51%), Gaps = 5/109 (4%)
 Frame = -2

Query: 69  QEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLVRV--CENIPIVLCGNKVD- 125
           QE+F  +R+ Y  +    +++F V    +++N+ N+H  ++RV   +  P++LC NKVD 
Sbjct: 508 QEEFSAMREQYMRKGDGFLLVFSVIDYQSFENMVNFHTQILRVKDRDTYPMILCANKVDL 329

Query: 126 IKDRKVKAKSIV-FHRKKNLQYYDISAKS-NYNFEKPFLWLARKLIGDP 172
           +  RKV  + +     +  + Y + SAK    N +  F  + R +   P
Sbjct: 328 VHQRKVSEEQVRDLATRLRIPYIETSAKDPPLNVDLAFHQVVRVIRAQP 182
>00552
          Length = 455

 Score = 42.0 bits (97), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 19/65 (29%), Positives = 34/65 (52%)
 Frame = -3

Query: 45  VEVHPLVFHTNRGPIKFNVWDTAGQEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNW 104
           V   P V+H         +WDTAGQE++  LR  +Y    C ++ F V +  + +++ +W
Sbjct: 180 VAASPDVWH-------HGIWDTAGQERYKSLRTPFYRGTDCCLLTFSVDNLKSLQSLSDW 22

Query: 105 HRDLV 109
           + + V
Sbjct: 21  YDEFV 7

 Score = 37.0 bits (84), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 15/36 (41%), Positives = 26/36 (72%)
 Frame = -1

Query: 11  FKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVE 46
            K+VL+GDGG GK++ + R ++ +F+ +   T+GVE
Sbjct: 443 LKVVLLGDGGVGKSSLMNRFVSNKFDAQSFHTIGVE 336
>36482
          Length = 686

 Score = 41.2 bits (95), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 32/111 (28%), Positives = 53/111 (47%), Gaps = 5/111 (4%)
 Frame = +2

Query: 29  RHLTGEFEKKYVATLGVEVHPLVFHT--NRGPIKFNVWDTAGQEKFGGLRDGYYIQAQCA 86
           R LT  F  +Y  TL        +HT      ++  + DTAGQ  +   ++GY + A C 
Sbjct: 11  RFLTRRFIGEYCPTLE---SVYKYHTVIEDDDVRLEILDTAGQGTYP-WKEGYALWADCF 178

Query: 87  IIMFDVTSRVTYKNVPNWHRDL--VRVCENIPIVLCGNKVD-IKDRKVKAK 134
           + ++ +  R +Y+ +    R +  VR   ++  VL  NK D + DR+V  K
Sbjct: 179 VFVYSINDRQSYEELVQVKRQVESVRKSTSLTAVLAANKTDLLHDRQVTQK 331
>08153
          Length = 1703

 Score = 39.3 bits (90), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 25/86 (29%), Positives = 39/86 (45%)
 Frame = +1

Query: 10  QFKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIKFNVWDTAGQ 69
           + ++++VG    GKTT + +   GE     + T+G  V  + +      I F VWD  GQ
Sbjct: 82  EVRILMVGLDAAGKTTILYKLKLGEIVTT-IPTIGFNVETVEYKN----ISFTVWDVGGQ 246

Query: 70  EKFGGLRDGYYIQAQCAIIMFDVTSR 95
           +K   L   Y+   Q  I + D   R
Sbjct: 247 DKIRPLWRHYFQNTQGLIFVVDSNDR 324
>14775
          Length = 380

 Score = 38.1 bits (87), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 21/74 (28%), Positives = 40/74 (54%), Gaps = 3/74 (4%)
 Frame = -2

Query: 23  KTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGP---IKFNVWDTAGQEKFGGLRDGY 79
           KT  ++R+  G F  + + T+ V      F+ +R     +++ +WDT G E +  L   +
Sbjct: 379 KTCLLRRYQKGFFMDRTMPTIAVLCSE--FNESRTDPLNVRYTLWDTGGAETYRSLWVSH 206

Query: 80  YIQAQCAIIMFDVT 93
           +  AQ A++++DVT
Sbjct: 205 FRGAQVALLVYDVT 164
>09204
          Length = 1051

 Score = 37.0 bits (84), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 24/101 (23%), Positives = 49/101 (48%), Gaps = 6/101 (5%)
 Frame = -3

Query: 71   KFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLVRVCENIPIVLCGNKVDI---- 126
            ++  +   YY  A+ AI+ FD+T + ++  +  W  +L +  E   + +CG K D+    
Sbjct: 1049 RYEAMSRIYYRGAKAAILCFDLTDKSSFDRIRFWIGELRQHEEECKLYICGTKFDLVHDD 870

Query: 127  KDRKVKAKSIVFHRKKNL--QYYDISAKSNYNFEKPFLWLA 165
             +R+   +S+      +   + Y+ S+ +  N EK F  +A
Sbjct: 869  PERRAVPRSVAKALADDCMAEIYETSSMTGDNIEKLFTKIA 747
>09827
          Length = 1201

 Score = 36.6 bits (83), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 38/168 (22%), Positives = 68/168 (40%), Gaps = 10/168 (5%)
 Frame = -3

Query: 11   FKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIKFNVWDTAGQE 70
             ++++VG    GKTT + +   GE     + T+G  V  + +      I F VWD  GQ+
Sbjct: 1112 MRILMVGLDAAGKTTILYKLKLGEIVTT-IPTIGFNVETVEYKN----ISFTVWDVGGQD 948

Query: 71   KFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLVRV-----CENIPIVLCGNKVD 125
            K   L   Y+   Q  I + D   +   + V     +L R+       +  +++  NK D
Sbjct: 947  KIRPLWRHYFQNTQGLIFVVDSNDK---ERVQEAREELTRMLNEDELRDAVLLVFANKQD 777

Query: 126  IKDRKVKA---KSIVFHRKKNLQYY--DISAKSNYNFEKPFLWLARKL 168
            +      A   + +  H  +N  +Y     A +     +   WL+ +L
Sbjct: 776  LPHAMATAEITEKLGLHGLRNRTWYIQSTCATTGDGLYEGLDWLSNQL 633
>33605
          Length = 888

 Score = 35.4 bits (80), Expect = 0.019,   Method: Compositional matrix adjust.
 Identities = 25/91 (27%), Positives = 41/91 (45%)
 Frame = +1

Query: 6   EPQVQFKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIKFNVWD 65
           + + + +L+++G    GKTT +K+   GE       TLG  +  L    +RG  K NVWD
Sbjct: 484 QKEKEVRLLMLGLDNAGKTTILKK-FNGEDIDTISPTLGFNIKTL---EHRG-FKLNVWD 648

Query: 66  TAGQEKFGGLRDGYYIQAQCAIIMFDVTSRV 96
             GQ+        Y+      + + D   R+
Sbjct: 649 VGGQQSLRSYWRNYFESTDGLVWVVDSADRM 741
>10708
          Length = 2775

 Score = 35.4 bits (80), Expect = 0.019,   Method: Compositional matrix adjust.
 Identities = 14/44 (31%), Positives = 24/44 (54%)
 Frame = -2

Query: 59   IKFNVWDTAGQEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVP 102
            ++  +WDTAGQE +  LR   Y      ++ F + S  + +N+P
Sbjct: 2723 VELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIP 2592

 Score = 30.4 bits (67), Expect = 0.52,   Method: Compositional matrix adjust.
 Identities = 14/48 (29%), Positives = 28/48 (58%)
 Frame = -3

Query: 81   IQAQCAIIMFDVTSRVTYKNVPNWHRDLVRVCENIPIVLCGNKVDIKD 128
            + + CA  +  +T+  T  ++  W  ++   C N+PI+L GNK D+++
Sbjct: 2647 MSSLCASPLTALTAWRT--SLKKWTPEVRHFCPNVPIILVGNKKDLRN 2510
>20290
          Length = 1550

 Score = 32.7 bits (73), Expect = 0.10,   Method: Compositional matrix adjust.
 Identities = 19/46 (41%), Positives = 26/46 (56%), Gaps = 3/46 (6%)
 Frame = +1

Query: 13  LVLVGDGGTGKTTFVKRHLTGEFE---KKYVATLGVEVHPLVFHTN 55
           LVL+G+ GTGKTTF+ R L G  +   +  +  L +   P  FH N
Sbjct: 787 LVLLGENGTGKTTFI-RMLAGNLQPDGEVELPMLNISYKPQKFHRN 921
>10862
          Length = 2896

 Score = 32.3 bits (72), Expect = 0.16,   Method: Compositional matrix adjust.
 Identities = 15/36 (41%), Positives = 18/36 (50%)
 Frame = -3

Query: 60   KFNVWDTAGQEKFGGLRDGYYIQAQCAIIMFDVTSR 95
            +FNVWD  GQ+K   L   YY   Q  I + D   R
Sbjct: 2483 QFNVWDVGGQDKIRPLWRHYYTGTQGLIFVVDCADR 2376
>13795
          Length = 642

 Score = 29.6 bits (65), Expect = 0.97,   Method: Compositional matrix adjust.
 Identities = 17/33 (51%), Positives = 20/33 (60%), Gaps = 1/33 (3%)
 Frame = -1

Query: 1   MAAQGEPQVQFK-LVLVGDGGTGKTTFVKRHLT 32
           M A  E Q Q K L ++GDGGT  T+FV   LT
Sbjct: 204 MTAGSEVQAQAKRLQILGDGGTQPTSFVNSVLT 106
>18248
          Length = 466

 Score = 28.9 bits (63), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 13/24 (54%), Positives = 19/24 (79%)
 Frame = +3

Query: 13  LVLVGDGGTGKTTFVKRHLTGEFE 36
           +V++G+ GTGKTTF+K  L G+ E
Sbjct: 108 IVMLGENGTGKTTFIKM-LAGKLE 176
>33029
          Length = 1133

 Score = 28.9 bits (63), Expect = 1.7,   Method: Compositional matrix adjust.
 Identities = 11/30 (36%), Positives = 16/30 (53%)
 Frame = +1

Query: 77  DGYYIQAQCAIIMFDVTSRVTYKNVPNWHR 106
           D  +I   CAI M    ++ ++KN P W R
Sbjct: 682 DCKFILGTCAIFMQQTDTKPSHKNTPQWAR 771
>11357
          Length = 1307

 Score = 27.3 bits (59), Expect = 4.6,   Method: Compositional matrix adjust.
 Identities = 14/42 (33%), Positives = 27/42 (64%), Gaps = 4/42 (9%)
 Frame = -2

Query: 145 QYYDISA---KSNYNFEKPFLWLAR-KLIGDPNLEFVAMPAL 182
           ++YD S+   K+NY+F+K F+W +  +L    +LE++ +  L
Sbjct: 733 EHYDFSSCISKNNYSFKKGFIWFSCIQLFKRGSLEYMLVFVL 608
>02253
          Length = 1110

 Score = 26.9 bits (58), Expect = 6.0,   Method: Compositional matrix adjust.
 Identities = 18/61 (29%), Positives = 26/61 (42%), Gaps = 1/61 (1%)
 Frame = +3

Query: 38  KYVATLG-VEVHPLVFHTNRGPIKFNVWDTAGQEKFGGLRDGYYIQAQCAIIMFDVTSRV 96
           +Y+A L  + VH  V   +    KFN+ DT+ +  F       +I   C       T RV
Sbjct: 213 EYLAQLDKLFVHQKVERNDLASTKFNIMDTSQKPAFEAAESSSFISRLCCFGFRGFTYRV 392

Query: 97  T 97
           T
Sbjct: 393 T 395
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|116174793|ref|NP_115999.2| spectrin beta 4 [Mus
musculus]
         (2561 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

19002                                                                 373   e-103
26578                                                                 145   2e-34
17613                                                                  85   1e-31
19147                                                                 122   2e-28
34010                                                                 113   1e-24
29446                                                                  94   1e-18
05733                                                                  76   2e-13
34417                                                                  73   2e-12
09711                                                                  64   6e-10
11159                                                                  63   2e-09
09100                                                                  62   2e-09
22703                                                                  62   4e-09
19246                                                                  61   6e-09
25051                                                                  60   1e-08
28965                                                                  55   3e-07
32371                                                                  38   5e-07
38533                                                                  53   2e-06
04951                                                                  47   7e-05
29517                                                                  46   3e-04
18202                                                                  44   0.001
32088                                                                  37   0.071
18556                                                                  34   0.75 
11916                                                                  32   4.6  
17567                                                                  31   5.2  
>19002
          Length = 842

 Score =  373 bits (957), Expect = e-103,   Method: Composition-based stats.
 Identities = 184/280 (65%), Positives = 219/280 (78%)
 Frame = -2

Query: 92  DGFVLTRLLEVLSGEQLPRPTRGRMRIHSLENVDKALQFLKEQRVHLENVGSHDIVDGNH 151
           DG +L +LLEV    ++    +G+MRIH LENVDKAL FL EQRVHLEN+G+HDIVDG+ 
Sbjct: 841 DGKMLMKLLEVRVRGEIASDXKGKMRIHCLENVDKALTFLHEQRVHLENMGAHDIVDGSS 662

Query: 152 RLTLGLVWTIILRFQIQVIKIETEDNRETRSAKDALLLWCQMKTAGYPEVNIQNFTTSWR 211
           RLTLGL+WTIILRFQIQ I IE  DN ET+SAKDALLLWCQMKTAGYP VN++NFTTSWR
Sbjct: 661 RLTLGLIWTIILRFQIQDIMIEEVDNSETKSAKDALLLWCQMKTAGYPNVNVRNFTTSWR 482

Query: 212 DGLAFNALIHRHRPDLVDLSKLTKSNANYNLQRAFRTAEQHLGLARLLDPEDVNMEAPDE 271
           DGLAFNA+IH+HRPDLV   +L KS+A  NLQ AF  AE  LGL  LL+PEDVN+E PDE
Sbjct: 481 DGLAFNAIIHKHRPDLVQYDRLHKSSAIQNLQNAFTVAEDKLGLTALLEPEDVNVEYPDE 302

Query: 272 KSIITYVVSFYHYFSKMKALAVEGKRIGKVLDQVLEVDKIIERYXXXXXXXXXWIHRTVD 331
           KSIITYVV++YHYFSKMKA +V+GKRIGKV+D  +  +  IE Y         WI +T+ 
Sbjct: 301 KSIITYVVTYYHYFSKMKADSVQGKRIGKVIDNAINTENSIEEYETLTSDLLEWIEQTIV 122

Query: 332 LISNQKFANSLSGVQQQLQAFTAYCTLEKPVKFQEKGNLE 371
           ++ +++FANSL+GVQQQL AF  Y  +EKP KF EKGNLE
Sbjct: 121 ILRDRQFANSLTGVQQQLAAFNTYRIVEKPPKFDEKGNLE 2
>26578
          Length = 430

 Score =  145 bits (365), Expect = 2e-34,   Method: Compositional matrix adjust.
 Identities = 70/137 (51%), Positives = 101/137 (73%)
 Frame = +1

Query: 1714 ERRVSLEQQYWLYQLSRQVDELEHWIAEKEVVAGSPELGQDFEHVSVLQEKFSEFASETG 1773
            ERR  LE+ + LY L R++ +L  WIAEK +VAGS + GQD+EHVS+L+E+F EFA +T 
Sbjct: 1    ERRGKLEEVFKLYTLHREIYDLLQWIAEKSLVAGSNDPGQDYEHVSMLKEQFKEFARDTE 180

Query: 1774 TAGRERLAAVNQMVDELIECGHTAAATMAEWKDGLNEAWAELLELMGTRAQLLAASRELH 1833
            + G+ER+A+ N++ D+LI   H+ +A++AEWKD +NEAWA+LLEL+ TR QLL +S ELH
Sbjct: 181  SMGQERVASANEICDQLIALDHSDSASIAEWKDNVNEAWADLLELIDTRTQLLQSSWELH 360

Query: 1834 KFFSDARELQGQIEEKR 1850
            KF  + ++   +I   R
Sbjct: 361  KFLYECKDTLERITRNR 411

 Score = 36.2 bits (82), Expect = 0.16,   Method: Compositional matrix adjust.
 Identities = 26/121 (21%), Positives = 56/121 (46%), Gaps = 1/121 (0%)
 Frame = +1

Query: 1609 RQQTLDAAFQVEQYYFDVAEVEAWLGEQELLMMSEDKGKDEQSTXXXXXXXXXXEQGVEN 1668
            R+  L+  F++   + ++ ++  W+ E+ L+  S D G+D +             +  E+
Sbjct: 4    RRGKLEEVFKLYTLHREIYDLLQWIAEKSLVAGSNDPGQDYEHVSMLKEQFKEFARDTES 183

Query: 1669 Y-EESIAQLSRQCRALLEMGHPDSEQISRRQSQVDRLYVALKELGEERRVSLEQQYWLYQ 1727
              +E +A  +  C  L+ + H DS  I+  +  V+  +  L EL + R   L+  + L++
Sbjct: 184  MGQERVASANEICDQLIALDHSDSASIAEWKDNVNEAWADLLELIDTRTQLLQSSWELHK 363

Query: 1728 L 1728
             
Sbjct: 364  F 366
>17613
          Length = 1108

 Score = 84.7 bits (208), Expect(2) = 1e-31,   Method: Compositional matrix adjust.
 Identities = 45/132 (34%), Positives = 67/132 (50%), Gaps = 1/132 (0%)
 Frame = +3

Query: 243 QRAFRTAEQHLGLARLLDPED-VNMEAPDEKSIITYVVSFYHYFSKMKALAVEGKRIGKV 301
           Q  F    +HL + R+LDPED VN   PDE+S++ YV S+YH FS  +       RI KV
Sbjct: 366 QHCF*HRRKHLDIPRMLDPEDMVNSAKPDERSVMAYVSSYYHAFSGAQQAETAANRICKV 545

Query: 302 LDQVLEVDKIIERYXXXXXXXXXWIHRTVDLISNQKFANSLSGVQQQLQAFTAYCTLEKP 361
           L    E ++++E Y         WI RT   + N+   N+L G + +L  F  Y   +KP
Sbjct: 546 LKVNQENERLMEEYERLASDLLEWIRRTRPWLENRVTDNTLPGTRHKLDEFRDYRRKQKP 725

Query: 362 VKFQEKGNLEVL 373
             ++ + +   L
Sbjct: 726 PSWRTRPSWRTL 761

 Score = 72.8 bits (177), Expect(2) = 1e-31,   Method: Composition-based stats.
 Identities = 52/139 (37%), Positives = 70/139 (50%), Gaps = 4/139 (2%)
 Frame = +1

Query: 116 MRIHSLENVDKALQFLKEQRVHLENVGSHDIVDGNHRLTLGLVWTIILRFQI----QVIK 171
           MR H + NV+KAL ++  QR      G H       R          +R+ +    QV  
Sbjct: 4   MRFHKIANVNKALDYIDLQR---GQTGLH-----RSRRNC*RQRKDDIRYDLDNYPQVCH 159

Query: 172 IETEDNRETRSAKDALLLWCQMKTAGYPEVNIQNFTTSWRDGLAFNALIHRHRPDLVDLS 231
                +R T   +  +++    KTA Y  VN+QNF  S++DGLAF ALIHRHRP+L+D  
Sbjct: 160 -PRHHSRRTHCQRRTVIV-VPAKTAPYKNVNVQNFHLSFKDGLAFCALIHRHRPELIDYH 333

Query: 232 KLTKSNANYNLQRAFRTAE 250
            L+K N   NL  AF  AE
Sbjct: 334 SLSKDNPLENLNTAFDIAE 390

 Score = 47.0 bits (110), Expect = 9e-05,   Method: Compositional matrix adjust.
 Identities = 31/111 (27%), Positives = 50/111 (45%), Gaps = 1/111 (0%)
 Frame = +2

Query: 363 KFQEKGNLEVLLFSIQSKLRAHNRRLFVPREGCGIWDIDKAWGXXXXXXXXXXXXXXXXX 422
           K ++K  LE    ++Q++LR  NR  ++P EG  + DI  AW                  
Sbjct: 728 KLEDKAKLENSFNTLQTRLRLSNRPAYLPTEGKMVSDIANAWKGLEHAEKGFEEWLLSEL 907

Query: 423 XXXXKLELLAQRFDHKVAMRESWLNENQRLVSQDNFG-YELPAVEAAMKKH 472
               +L+ LAQ+F HK  + E W    + ++   +F    L  ++A  KKH
Sbjct: 908 QRLERLDHLAQKFRHKCEIHEEWSQGKEDMLQSRDFKQCRLNELKAMKKKH 1060
>19147
          Length = 474

 Score =  122 bits (307), Expect(2) = 2e-28,   Method: Composition-based stats.
 Identities = 57/106 (53%), Positives = 77/106 (72%)
 Frame = +1

Query: 130 FLKEQRVHLENVGSHDIVDGNHRLTLGLVWTIILRFQIQVIKIETEDNRETRSAKDALLL 189
           ++  + V L ++G+ +IVDGN ++TLG++WTIILRF IQ I +E        +AK+ LLL
Sbjct: 49  YIASKGVKLVSIGAEEIVDGNVKMTLGMIWTIILRFAIQDITVEE------LTAKEGLLL 210

Query: 190 WCQMKTAGYPEVNIQNFTTSWRDGLAFNALIHRHRPDLVDLSKLTK 235
           WCQ KTA Y  VN+QNF  S++DGLAF ALIHRHRP+L+D   L+K
Sbjct: 211 WCQRKTAPYKNVNVQNFHLSFKDGLAFCALIHRHRPELIDYHSLSK 348

 Score = 24.3 bits (51), Expect(2) = 2e-28,   Method: Composition-based stats.
 Identities = 10/21 (47%), Positives = 15/21 (71%)
 Frame = +3

Query: 115 RMRIHSLENVDKALQFLKEQR 135
           +MR H + NV+KAL+  + QR
Sbjct: 3   KMRFHKIANVNKALELHRLQR 65
>34010
          Length = 832

 Score =  113 bits (282), Expect = 1e-24,   Method: Compositional matrix adjust.
 Identities = 61/146 (41%), Positives = 89/146 (60%)
 Frame = +3

Query: 1964 ADKPRDVSSVEVLMNYHQGLKTELEARVPELATCQELGRSLLLNKSAMADEIQAQLDKLG 2023
            A KPRDVS VE+LMN HQ LK E++AR    A C  LGR LL  K    +E++ +L +L 
Sbjct: 78   AGKPRDVSGVELLMNNHQSLKAEIDAREENFAICINLGRDLLNRKHYRQEEVREKLIQLT 257

Query: 2024 SRKEEVSEKWDRHWEWLQQMLEVHQFAQEAVVADAWLTAQEPLLQSRELGSSVDEVEQLI 2083
              + ++++ W   WE LQ +LEV+QFA++A VA+AWL AQE    +++LG ++D VE LI
Sbjct: 258  LERLDMTDLWKDRWEHLQLILEVYQFARDAAVAEAWLVAQEQYFLNQDLGDTLDAVENLI 437

Query: 2084 RRHEAFRKAAAAWEERFSSLRRLTTI 2109
            +  +  +    A   +   LR+   I
Sbjct: 438  KSMKPLKSCCHA-RRKICCLRKTNHI 512

 Score = 34.7 bits (78), Expect = 0.53,   Method: Compositional matrix adjust.
 Identities = 36/122 (29%), Positives = 54/122 (44%), Gaps = 1/122 (0%)
 Frame = +3

Query: 1115 PRSLEEADGLLARHAALKEEVDQREEDYARIVXXXXXXXXXXXXXXXXXXXXDEWLPHLE 1174
            PR +   + L+  H +LK E+D REE++A  +                     E L  L 
Sbjct: 87   PRDVSGVELLMNNHQSLKAEIDAREENFAICINLGRDLLNRKHYRQEEVR---EKLIQLT 257

Query: 1175 VGWHKLLGLWEERREAL-VQAHVYQLFLRDLCQALAVLRNQEVALSGAELPCTVESVEEA 1233
            +    +  LW++R E L +   VYQ F RD   A A L  QE      +L  T+++VE  
Sbjct: 258  LERLDMTDLWKDRWEHLQLILEVYQ-FARDAAVAEAWLVAQEQYFLNQDLGDTLDAVENL 434

Query: 1234 MK 1235
            +K
Sbjct: 435  IK 440
>29446
          Length = 1445

 Score = 93.6 bits (231), Expect = 1e-18,   Method: Compositional matrix adjust.
 Identities = 55/138 (39%), Positives = 75/138 (54%), Gaps = 5/138 (3%)
 Frame = +3

Query: 63   VQKKTFTKWVNSHLARVGCHIGDLYADLRDGFVLTRLLEVLSGEQLPRPT-RGRMRIHSL 121
            +QK TFT+W N HL  V   I DL +D  DG  L  L+EVLSG++      R   R   L
Sbjct: 999  IQKNTFTRWANEHLRTVNKAIADLESDFSDGLRLVALIEVLSGKKFKHVNKRPNFRTQKL 1178

Query: 122  ENVDKALQFLKEQR-VHLENVGSHDIVDGNHRLTLGLVWTIILRFQIQVIKIETEDNRET 180
            ENV   L+FL++   + + N+ S DIVD   +L LGL+WT+IL + I +   E E+   +
Sbjct: 1179 ENVTLTLKFLEDDEGIRIVNIDSTDIVDKKLKLILGLIWTLILHYSISMPMWEGEEPTPS 1358

Query: 181  R---SAKDALLLWCQMKT 195
                + K  LL W Q K 
Sbjct: 1359 EGGPTPKQRLLNWIQSKV 1412
>05733
          Length = 1021

 Score = 76.3 bits (186), Expect = 2e-13,   Method: Compositional matrix adjust.
 Identities = 41/103 (39%), Positives = 61/103 (59%), Gaps = 3/103 (2%)
 Frame = +2

Query: 186 ALLLWCQ--MKTAGYPEVNIQNFTTSWRDGLAFNALIHRHRPDLVDLSKLTKSNANYNLQ 243
           +LL WCQ  +    Y  V+I +FT+SWR GLAF ALIH  RP L+  + L +     N Q
Sbjct: 467 SLLRWCQRVLNXGTYRGVHIIDFTSSWRSGLAFCALIHAFRPHLISPASLMECETVKNNQ 646

Query: 244 RAFRTAEQHLGLARLLDPEDVNMEA-PDEKSIITYVVSFYHYF 285
            AF  A++ LG+A ++  ED+   A PD+ +++ Y+  F+  F
Sbjct: 647 LAFDVAQKELGIAPVMRGEDMAACAVPDKLTMVAYLSQFHELF 775
>34417
          Length = 1096

 Score = 72.8 bits (177), Expect = 2e-12,   Method: Composition-based stats.
 Identities = 37/81 (45%), Positives = 49/81 (60%), Gaps = 1/81 (1%)
 Frame = +2

Query: 206 FTTSWRDGLAFNALIHRHRPDLVDLSKLTKSNANYNLQRAFRTAEQHLGLARLLDPED-V 264
            ++ W +GLAF ALIH   PD  D S+L   N  YN + AF TAE+   ++ LLD ED +
Sbjct: 35  LSSCWNNGLAFCALIHHFYPDAFDYSQLQPQNRRYNFELAFDTAEKLADISPLLDVEDMI 214

Query: 265 NMEAPDEKSIITYVVSFYHYF 285
            M+ PD K + TYV SFY + 
Sbjct: 215 KMKNPDWKCVFTYVQSFYRHL 277
>09711
          Length = 3041

 Score = 64.3 bits (155), Expect = 6e-10,   Method: Composition-based stats.
 Identities = 56/222 (25%), Positives = 104/222 (46%), Gaps = 16/222 (7%)
 Frame = +1

Query: 59   EREAVQKKTFTKWVNSHLARVGCHIGDLYADLRDGFVLTRLLEVLS------GEQLPRPT 112
            + E+ ++KT+  W+NS    V   +  LY+DL DG ++ +L + +        +   +  
Sbjct: 835  KEESREEKTYRNWMNS--LGVSPFVHHLYSDLYDGLIIFQLYDYIQPGLVDWSKVKKKFN 1008

Query: 113  RGRMRIHSLENVDKALQF---LKEQRVHLENVGSHDIVDGNHRLTLGLVWTIILRFQIQV 169
            + + R   +EN + A++    +K  +V L  +   DI+DGN  LTLGLVW ++  + + +
Sbjct: 1009 KLKARFERIENCNYAVELGPQVKLVKVKLVGIAGQDILDGNPVLTLGLVWQLMRAYTLAI 1188

Query: 170  IKIETEDNRETRSAKDALLLWCQMKTAGYPEVNIQNFTT-SWRDGLAFNALIHRHRPDLV 228
            +   TE+N+    + + ++ W   K     +  I  F      DG+    +I   +P +V
Sbjct: 1189 LSKITENNKPI--SDNEIITWVNSKIK--KDDRISGFQDRKLNDGVIVARVIEAIKPGIV 1356

Query: 229  DLSKLTKSNANYNLQRAFRTAEQHLGLARLLD------PEDV 264
            +   +  S  +Y  Q     A   +GLAR +       PED+
Sbjct: 1357 NWDNIDCSARDY--QDRLTNARYAIGLARKIGAGVYALPEDI 1476

 Score = 38.9 bits (89), Expect = 0.030,   Method: Composition-based stats.
 Identities = 60/269 (22%), Positives = 111/269 (41%), Gaps = 29/269 (10%)
 Frame = +1

Query: 61  EAVQKKTFTKWVNSHLARV-GC-HIGDLYAD-------LRDGFVLTRLLEVLSGEQLPRP 111
           +A ++K F +W+N HL+    C H+  L AD       + DG +L +L+       +   
Sbjct: 43  KAGEQKAFAEWINRHLSDXPDCKHLLPLDADGTQLFGQMADGVLLCKLINHSVSNTIDER 222

Query: 112 TRGRMRI---HSLENVDKALQFLKEQRVHLENVGSHDIVDGNHRLTLGLVWTIILRFQIQ 168
           T  +  +      EN+  A+           N+G  D+  G   L LGL+W II    + 
Sbjct: 223 TINKQNLSLYRRHENLTLAVNSAGAIGCTTVNIGPEDLAAGRPHLVLGLLWQIIRIGLLS 402

Query: 169 VIKI-------------ETEDNRETRSAKDALLLWC--QMKTAGYPEVNIQNFTTSWRDG 213
            I +             ET ++    S +  LL W    +  AG  +  I NF    +D 
Sbjct: 403 DINLAHHPGLVNLLLDGETIEDLIRLSPEQILLRWVNYHLNRAGC-DRQIXNFGEDIKDS 579

Query: 214 LAFNALIHRHRPDL--VDLSKLTKSNANYNLQRAFRTAEQHLGLARLLDPEDVNMEAPDE 271
            A+  L+ +  P    V LS L+  + +   +   + A++ +G    +   DV   + ++
Sbjct: 580 EAYTHLLKQISPPSAGVTLSPLSVGDVHQRAECMLQEADK-IGCRSFVGASDV--VSGNQ 750

Query: 272 KSIITYVVSFYHYFSKMKALAVEGKRIGK 300
           K  + +V + ++ +  +    VE + + K
Sbjct: 751 KLNLAFVANLFNNYPALDTPQVEVEDVMK 837
>11159
          Length = 520

 Score = 62.8 bits (151), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 31/87 (35%), Positives = 47/87 (54%), Gaps = 4/87 (4%)
 Frame = +2

Query: 2437 RSWVSLYCVLSKGELGFYKDSKG----PASGGTHGGEPLLSLHKATSEVASDYKKKKHVF 2492
            RSW   +  L    L  +KD  G      S   H     + +H A + +A+DY KK+HVF
Sbjct: 65   RSWKMFFITLRDLVLYLHKDEHGFRKSQMSDNLHNA---IRIHHALATMANDYTKKQHVF 235

Query: 2493 KLQTQDGSEFLLQAKDEEEMNGWLEAV 2519
            +LQT D +E+L Q  D +E++ W+E +
Sbjct: 236  RLQTADQAEYLFQTSDSKELHSWVETI 316
>09100
          Length = 930

 Score = 62.4 bits (150), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 34/110 (30%), Positives = 58/110 (52%), Gaps = 7/110 (6%)
 Frame = +1

Query: 64  QKKTFTKWVNSHLAR-VGCH-IGDLYADLRDGFVLTRLLEVLSGEQLP-----RPTRGRM 116
           Q   +  W+NS L +  G H I DL  D+RDG V   ++ ++S +Q+P       T   M
Sbjct: 463 QLSAYMAWINSQLKKKPGAHLIEDLRHDMRDGVVFADVIHIVSKQQIPGIQNVPTTLDEM 642

Query: 117 RIHSLENVDKALQFLKEQRVHLENVGSHDIVDGNHRLTLGLVWTIILRFQ 166
           R    +NVD+ L F+ + R+ +  + S DIV+GN +  + L+  +   ++
Sbjct: 643 R----QNVDRVLHFMTQNRIKMHRISSRDIVEGNLKAVMRLILALAAHYK 780
>22703
          Length = 906

 Score = 61.6 bits (148), Expect = 4e-09,   Method: Compositional matrix adjust.
 Identities = 33/105 (31%), Positives = 59/105 (56%)
 Frame = -3

Query: 2001 GRSLLLNKSAMADEIQAQLDKLGSRKEEVSEKWDRHWEWLQQMLEVHQFAQEAVVADAWL 2060
            GRS + N   ++ EI+ ++ +L    E +    +   +  QQ LE  Q   E    +AW+
Sbjct: 859  GRSFIANGHFLSKEIEEKIKQLDQSLEGLIRNLEHRRKLHQQNLEAQQLRHEMEQIEAWM 680

Query: 2061 TAQEPLLQSRELGSSVDEVEQLIRRHEAFRKAAAAWEERFSSLRR 2105
              +EPLL+ ++ G S++  E+++RRH+ F K   A E+R ++L+R
Sbjct: 679  NLREPLLKEKKFGESIEGAEEMLRRHD*F*KTVTAQEDRVNALQR 545

 Score = 35.8 bits (81), Expect = 0.25,   Method: Compositional matrix adjust.
 Identities = 24/78 (30%), Positives = 41/78 (52%), Gaps = 3/78 (3%)
 Frame = -3

Query: 521 LTGLVGA---RRTRLEQNLALQKVFQEMVYMVDWMEEMQTQLLSRECGQHLVEADDLLQK 577
           L GL+     RR   +QNL  Q++  EM  +  WM   +  L  ++ G+ +  A+++L++
Sbjct: 784 LEGLIRNLEHRRKLHQQNLEAQQLRHEMEQIEAWMNLREPLLKEKKFGESIEGAEEMLRR 605

Query: 578 HGLLEGDIAAQSERVEAL 595
           H      + AQ +RV AL
Sbjct: 604 HD*F*KTVTAQEDRVNAL 551
>19246
          Length = 440

 Score = 60.8 bits (146), Expect = 6e-09,   Method: Composition-based stats.
 Identities = 39/106 (36%), Positives = 58/106 (54%), Gaps = 5/106 (4%)
 Frame = +2

Query: 2419 EGFLLRKRELDANRKSSNRSWVSLYCVLSKGELGFYKDSKGPASGGTHGG----EPLLSL 2474
            EG L  K  +   +K S+RSW  ++ VL    L   KD +    G TH      EP +S+
Sbjct: 8    EGPLWCKTAVSDGKKCSDRSWKQVWAVLRGHALFLIKDRR---DGSTHPTFSFEEPPISI 178

Query: 2475 HKATSEVASDY-KKKKHVFKLQTQDGSEFLLQAKDEEEMNGWLEAV 2519
                 ++A DY +K+KHVF+L T   S +LLQA+D+  M  W++A+
Sbjct: 179  KSCLVDIAHDYSRKRKHVFRLTTYSESVYLLQAEDKGTMMSWIQAI 316
>25051
          Length = 1017

 Score = 60.5 bits (145), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 38/115 (33%), Positives = 63/115 (54%), Gaps = 5/115 (4%)
 Frame = -2

Query: 2415 TVQHE-GFLLRKRELDANRKSS---NRSWVSLYCVLSKGELGFYKDSKGPASG-GTHGGE 2469
            TV+++ G+++RK  ++  R+ +    R W  +Y +L    L  YKD      G      +
Sbjct: 920  TVEYKKGYVMRKSCMEPGRRKTPFGKRGWRMVYTILRDLILYQYKDEHQVKKGQFVESSQ 741

Query: 2470 PLLSLHKATSEVASDYKKKKHVFKLQTQDGSEFLLQAKDEEEMNGWLEAVANSVA 2524
             ++ +H A +  ASDY KK+HVF+LQT D +E+L Q     E+  W++ + N VA
Sbjct: 740  NVVRIHHALATKASDYTKKQHVFRLQTADWAEYLFQTGGTIELQEWIDTI-NLVA 579
>28965
          Length = 421

 Score = 55.5 bits (132), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 38/138 (27%), Positives = 70/138 (50%)
 Frame = +2

Query: 1557 RREIQAHGPRLEEVLERAGVLASLRSPEAEAVRRGQEQLQSAWTGLREAAERRQQTLDAA 1616
            ++++Q H  ++ EV   A  L +   PE E +R+ QE++  AW  LR+ +  RQ+ L  A
Sbjct: 2    QKDLQNHEDKVVEVNTLAEQLVTDGHPEEETIRQKQEEVNEAWKRLRQLSLLRQERLYGA 181

Query: 1617 FQVEQYYFDVAEVEAWLGEQELLMMSEDKGKDEQSTXXXXXXXXXXEQGVENYEESIAQL 1676
             +++++  D  E  AW+ E++ ++ ++D G+D  S           E+ +   EE +  L
Sbjct: 182  HEIQRFNRDADETIAWIQEKDAVLSTDDYGRDLASVQTLQRKHEGVERDLAALEEKVNAL 361

Query: 1677 SRQCRALLEMGHPDSEQI 1694
              +   L  +    SEQI
Sbjct: 362  GTESVRLQGIHGDQSEQI 415

 Score = 50.8 bits (120), Expect = 8e-06,   Method: Compositional matrix adjust.
 Identities = 36/129 (27%), Positives = 67/129 (51%), Gaps = 1/129 (0%)
 Frame = +2

Query: 1663 EQGVENYEESIAQLSRQCRALLEMGHPDSEQISRRQSQVDRLYVALKELGEERRVSLEQQ 1722
            ++ ++N+E+ + +++     L+  GHP+ E I ++Q +V+  +  L++L   R+  L   
Sbjct: 2    QKDLQNHEDKVVEVNTLAEQLVTDGHPEEETIRQKQEEVNEAWKRLRQLSLLRQERLYGA 181

Query: 1723 YWLYQLSRQVDELEHWIAEKEVVAGSPELGQDFEHVSVLQEKFSEFASETGTAGRER-LA 1781
            + + + +R  DE   WI EK+ V  + + G+D   V  LQ K           G ER LA
Sbjct: 182  HEIQRFNRDADETIAWIQEKDAVLSTDDYGRDLASVQTLQRKHE---------GVERDLA 334

Query: 1782 AVNQMVDEL 1790
            A+ + V+ L
Sbjct: 335  ALEEKVNAL 361

 Score = 44.7 bits (104), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 33/126 (26%), Positives = 60/126 (47%)
 Frame = +2

Query: 485 RVQGVAELAQALAAEGYYDARRVAAQRDSVLRQWALLTGLVGARRTRLEQNLALQKVFQE 544
           +V  V  LA+ L  +G+ +   +  +++ V   W  L  L   R+ RL     +Q+  ++
Sbjct: 29  KVVEVNTLAEQLVTDGHPEEETIRQKQEEVNEAWKRLRQLSLLRQERLYGAHEIQRFNRD 208

Query: 545 MVYMVDWMEEMQTQLLSRECGQHLVEADDLLQKHGLLEGDIAAQSERVEALNAAALRFSQ 604
               + W++E    L + + G+ L     L +KH  +E D+AA  E+V AL   ++R   
Sbjct: 209 ADETIAWIQEKDAVLSTDDYGRDLASVQTLQRKHEGVERDLAALEEKVNALGTESVRLQG 388

Query: 605 LQGYQP 610
           + G Q 
Sbjct: 389 IHGDQS 406

 Score = 40.8 bits (94), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 30/104 (28%), Positives = 51/104 (49%), Gaps = 2/104 (1%)
 Frame = +2

Query: 1778 ERLAAVNQMVDELIECGHTAAATMAEWKDGLNEAWAELLELMGTRAQLLAASRELHKFFS 1837
            +++  VN + ++L+  GH    T+ + ++ +NEAW  L +L   R + L  + E+ +F  
Sbjct: 26   DKVVEVNTLAEQLVTDGHPEEETIRQKQEEVNEAWKRLRQLSLLRQERLYGAHEIQRFNR 205

Query: 1838 DARELQGQIEEKRRRLPRLTAPPEPRPSAS--SMQRTLRAFEHD 1879
            DA E    I+EK      L+     R  AS  ++QR     E D
Sbjct: 206  DADETIAWIQEKD---AVLSTDDYGRDLASVQTLQRKHEGVERD 328

 Score = 38.5 bits (88), Expect = 0.032,   Method: Compositional matrix adjust.
 Identities = 25/86 (29%), Positives = 45/86 (52%), Gaps = 7/86 (8%)
 Frame = +2

Query: 2025 RKEEVSEKWDR-------HWEWLQQMLEVHQFAQEAVVADAWLTAQEPLLQSRELGSSVD 2077
            ++EEV+E W R         E L    E+ +F ++A    AW+  ++ +L + + G  + 
Sbjct: 104  KQEEVNEAWKRLRQLSLLRQERLYGAHEIQRFNRDADETIAWIQEKDAVLSTDDYGRDLA 283

Query: 2078 EVEQLIRRHEAFRKAAAAWEERFSSL 2103
             V+ L R+HE   +  AA EE+ ++L
Sbjct: 284  SVQTLQRKHEGVERDLAALEEKVNAL 361

 Score = 37.7 bits (86), Expect = 0.068,   Method: Compositional matrix adjust.
 Identities = 27/95 (28%), Positives = 48/95 (50%), Gaps = 5/95 (5%)
 Frame = +2

Query: 1907 EAIASREQEVLQGWKEL--LAACEDARLHVSSTADALRFHSQARDLLSWMDGIAGQIGAA 1964
            E I  +++EV + WK L  L+     RL+     +  RF+  A + ++W+      +   
Sbjct: 89   ETIRQKQEEVNEAWKRLRQLSLLRQERLY--GAHEIQRFNRDADETIAWIQEKDAVLSTD 262

Query: 1965 DKPRDVSSVEVLMNYHQGLKTE---LEARVPELAT 1996
            D  RD++SV+ L   H+G++ +   LE +V  L T
Sbjct: 263  DYGRDLASVQTLQRKHEGVERDLAALEEKVNALGT 367

 Score = 36.2 bits (82), Expect = 0.16,   Method: Compositional matrix adjust.
 Identities = 20/71 (28%), Positives = 38/71 (53%)
 Frame = +2

Query: 932  RVLDVNQTVQELVEGGHPSSDEVRSCQDHLNSRWNRIVELVEQRKEEMSAVLLVENHVLE 991
            +V++VN   ++LV  GHP  + +R  Q+ +N  W R+ +L   R+E +     ++    +
Sbjct: 29   KVVEVNTLAEQLVTDGHPEEETIRQKQEEVNEAWKRLRQLSLLRQERLYGAHEIQRFNRD 208

Query: 992  VAEVRAQVREK 1002
              E  A ++EK
Sbjct: 209  ADETIAWIQEK 241

 Score = 32.3 bits (72), Expect = 2.9,   Method: Compositional matrix adjust.
 Identities = 18/67 (26%), Positives = 31/67 (46%)
 Frame = +2

Query: 774 FGADLDGLLDWLRDAYRLAAAGDFGHDEASSRRLARQHRALTGEVEAHRGPVGGLRRQLA 833
           F  D D  + W+++   + +  D+G D AS + L R+H  +  ++ A    V  L  +  
Sbjct: 197 FNRDADETIAWIQEKDAVLSTDDYGRDLASVQTLQRKHEGVERDLAALEEKVNALGTESV 376

Query: 834 TLGGASG 840
            L G  G
Sbjct: 377 RLQGIHG 397

 Score = 30.8 bits (68), Expect = 7.2,   Method: Compositional matrix adjust.
 Identities = 12/40 (30%), Positives = 23/40 (57%)
 Frame = +2

Query: 433 QRFDHKVAMRESWLNENQRLVSQDNFGYELPAVEAAMKKH 472
           QRF+       +W+ E   ++S D++G +L +V+   +KH
Sbjct: 191 QRFNRDADETIAWIQEKDAVLSTDDYGRDLASVQTLQRKH 310

 Score = 30.8 bits (68), Expect = 7.3,   Method: Compositional matrix adjust.
 Identities = 15/54 (27%), Positives = 31/54 (57%)
 Frame = +2

Query: 1509 ASKELHQVAHDLDDELAWVQERLPLAMQTERGTGLQAVQQHIKKNQGLRREIQA 1562
             + E+ +   D D+ +AW+QE+  +    + G  L +VQ   +K++G+ R++ A
Sbjct: 176  GAHEIQRFNRDADETIAWIQEKDAVLSTDDYGRDLASVQTLQRKHEGVERDLAA 337
>32371
          Length = 625

 Score = 37.7 bits (86), Expect(2) = 5e-07,   Method: Compositional matrix adjust.
 Identities = 20/48 (41%), Positives = 26/48 (54%), Gaps = 1/48 (2%)
 Frame = -2

Query: 225 PDLVDLSKLTKSNANYNLQRAFRTAEQHLGLARLLDPED-VNMEAPDE 271
           PDL+D   L+K N  YN   AF  AEQ L +   L+  D V +  PD+
Sbjct: 549 PDLIDYDSLSKENVLYNNNLAFTVAEQELDIPAFLEAADMVALRTPDK 406

 Score = 36.2 bits (82), Expect(2) = 5e-07,   Method: Composition-based stats.
 Identities = 14/24 (58%), Positives = 19/24 (79%)
 Frame = -1

Query: 201 VNIQNFTTSWRDGLAFNALIHRHR 224
           V+I++   SWR+GLAF A+IHR R
Sbjct: 622 VDIKDLLVSWRNGLAFCAIIHRFR 551
>38533
          Length = 380

 Score = 52.8 bits (125), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 37/125 (29%), Positives = 58/125 (46%), Gaps = 8/125 (6%)
 Frame = +1

Query: 1520 LDDELAWVQ-ERLPLAMQTERGTGLQAVQQHIKKNQGLRREIQAHGPRLEEVLERAGVLA 1578
            ++DEL+W   +R P+A  T+ G  L AVQ  +KK+Q L  EI AH P ++ V   A  + 
Sbjct: 1    VEDELSWYY*DRKPIAESTDLGNSLTAVQNLMKKHQALESEIVAHEPLIDAVATSAQQMI 180

Query: 1579 SLRSPEAEAVRRGQEQLQSAWTGLREAAERRQQTL-------DAAFQVEQYYFDVAEVEA 1631
              +             +Q+    L   A+R Q             F  +++Y +V EVE 
Sbjct: 181  RTK-------HFATADIQTRLDDLTSPAQRSQVFYLL*KVETAGCFGAQKFYMEVNEVEL 339

Query: 1632 WLGEQ 1636
            W+ E+
Sbjct: 340  WMNEK 354
>04951
          Length = 2852

 Score = 47.4 bits (111), Expect = 7e-05,   Method: Composition-based stats.
 Identities = 41/154 (26%), Positives = 75/154 (48%), Gaps = 10/154 (6%)
 Frame = +1

Query: 121 LENVDKALQF---LKEQRVHLENVGSHDIVDGNHRLTLGLVWTIILRFQIQVIKIETEDN 177
           +EN + A+Q    +K  ++ L  +G  DI DGN  LTLGLVW ++  + + ++   TED 
Sbjct: 7   IENCEYAVQLGPQMKVCKMKLVGIGGKDIHDGNPVLTLGLVWQLMRAYTLAILSKLTEDK 186

Query: 178 RETRSAKDALLLWCQMKTAGYPEVNIQNFTTS-WRDGLAFNALIHRHRPDLVDLSKLTKS 236
           +  + ++  ++ W   K     +  I +F  S   DG+    +I   +P +V+   +  +
Sbjct: 187 KPIQDSE--IVDWVNSKVK--KDERIGSFQDSKLNDGVIVAKVIESIKPGIVNWENINPN 354

Query: 237 NANYNLQRAFRTAEQHLGLARLLD------PEDV 264
            +  + + A   A   +GLAR +       PED+
Sbjct: 355 ASEPDDRLA--NARYAIGLARKIGAGVYALPEDI 450
>29517
          Length = 622

 Score = 45.8 bits (107), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 22/49 (44%), Positives = 31/49 (63%)
 Frame = -1

Query: 2482 ASDYKKKKHVFKLQTQDGSEFLLQAKDEEEMNGWLEAVANSVAEHAEIA 2530
            A+DY K+ +VF+L+   GSE+L QAKD  E + W+  + NSV    E A
Sbjct: 589  AADYSKRPYVFRLKLSSGSEYLFQAKDAAERDTWIGRI-NSVTGGREPA 446
>18202
          Length = 424

 Score = 43.9 bits (102), Expect = 0.001,   Method: Composition-based stats.
 Identities = 34/133 (25%), Positives = 59/133 (44%), Gaps = 6/133 (4%)
 Frame = -1

Query: 66  KTFTKWVNSHLARVGCHIGDLYADLRDGFVLTRLLEVLSGEQLPRPTRGRMRIHSLENVD 125
           + +  W NS L  V   + ++ + +++G VL  L++VL+      P  G +         
Sbjct: 385 QVYLSWANSVLCEVNSSVENV-SSIQEGRVLCELIDVLA------PEAGLLDKVQASGKS 227

Query: 126 KALQFLKEQRVHLENVG------SHDIVDGNHRLTLGLVWTIILRFQIQVIKIETEDNRE 179
               F+     H++N G      + DI+DG+ +  L ++W +IL + I  I       R 
Sbjct: 226 GQRAFIYAALDHMKNHGIKIVFSTQDIMDGDIKSLLDVMWLLILNYGIHFIG-NNSFQRS 50

Query: 180 TRSAKDALLLWCQ 192
             + K  LL WCQ
Sbjct: 49  VGAGKKNLLDWCQ 11
>32088
          Length = 1928

 Score = 37.4 bits (85), Expect = 0.071,   Method: Composition-based stats.
 Identities = 28/111 (25%), Positives = 44/111 (39%), Gaps = 12/111 (10%)
 Frame = +1

Query: 64   QKKTFTKWVN---------SHLARVGCHIGDLYADLRDGFVLTRLLEVLSGEQLPRPTRG 114
            ++K F  W+N          HL  V     DL+  + DG +L +L+       +      
Sbjct: 1264 EQKAFAAWINRHLKDDPDCKHLMEVNEEGDDLFKKVGDGILLCKLINHSVSNTIDERAIN 1443

Query: 115  RMRI---HSLENVDKALQFLKEQRVHLENVGSHDIVDGNHRLTLGLVWTII 162
            +  +   H  EN+  A+           N+G  D+  G   L LGL+W II
Sbjct: 1444 KSNLNVYHRHENLTLAVNSAGSIGCTTVNIGPEDLAAGRPHLVLGLLWQII 1596
>18556
          Length = 799

 Score = 34.3 bits (77), Expect = 0.75,   Method: Compositional matrix adjust.
 Identities = 21/75 (28%), Positives = 37/75 (49%), Gaps = 1/75 (1%)
 Frame = +2

Query: 186 ALLLWCQMKTAGYP-EVNIQNFTTSWRDGLAFNALIHRHRPDLVDLSKLTKSNANYNLQR 244
           +LL W  ++ A Y     ++  +  +R+G    ALI R RPDL+D +     +     + 
Sbjct: 44  SLLRWISVQLAAYQFTAELKEPSDVFRNGRVLCALISRFRPDLIDYAATKDMSPLECNEL 223

Query: 245 AFRTAEQHLGLARLL 259
           AF   E+ L + R++
Sbjct: 224 AFAVLERELHIDRIM 268
>11916
          Length = 2024

 Score = 31.6 bits (70), Expect = 4.6,   Method: Composition-based stats.
 Identities = 23/87 (26%), Positives = 46/87 (52%), Gaps = 1/87 (1%)
 Frame = +1

Query: 278 VVSFYHYFSKMKALAVEGKRIGKVLDQVLEVDKIIERYXXXXXXXXXWIHRTVDLISNQK 337
           +V  YH+FS +    +  ++  K++D +L++D+   +            + T  ++ NQK
Sbjct: 208 LVHNYHFFS-LSTFILNKQQ--KMIDSLLDMDQSHTKLTT---------NETNKIMLNQK 351

Query: 338 FANSLSGVQQQ-LQAFTAYCTLEKPVK 363
           ++ +  G Q+Q L  F+++C L  PVK
Sbjct: 352 YSITSHGKQKQYLDFFSSFCCLACPVK 432
>17567
          Length = 448

 Score = 31.2 bits (69), Expect = 5.2,   Method: Compositional matrix adjust.
 Identities = 34/153 (22%), Positives = 63/153 (41%), Gaps = 5/153 (3%)
 Frame = -3

Query: 1607 ERRQQTLDAAFQVEQYYFDVAEVEAWLGEQELLMMSEDKGKDEQSTXXXXXXXXXXEQGV 1666
            E R+ TL     +   + ++  ++  L E +  ++ ED GK  Q+T          E  +
Sbjct: 428  ESRKSTLSGYNNLMAMFREIESIQEELKEVQSKVVGEDYGKHLQATQDMLEQHSLQEAQL 249

Query: 1667 ENYEESIAQLSRQCRALLEMGHPD-----SEQISRRQSQVDRLYVALKELGEERRVSLEQ 1721
            +     + +L+R+ +   E          + Q++  Q+Q D+           RR  LE 
Sbjct: 248  QALTRRVRKLNRKSQGAQEQSLDKRLEALNAQLNNVQAQSDK-----------RRQGLET 102

Query: 1722 QYWLYQLSRQVDELEHWIAEKEVVAGSPELGQD 1754
                YQ  +  +E + W+ E+     SP LG+D
Sbjct: 101  AQQYYQFLQDTEEEDRWVGERIDAVRSPSLGKD 3
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31982302|ref|NP_032240.2| histidyl-tRNA synthetase
[Mus musculus]
         (509 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

18389                                                                 371   e-103
12536                                                                  33   0.002
20113                                                                  29   4.3  
30183                                                                  29   5.1  
>18389
          Length = 664

 Score =  371 bits (953), Expect = e-103,   Method: Compositional matrix adjust.
 Identities = 172/221 (77%), Positives = 193/221 (87%)
 Frame = +2

Query: 76  VFDVIIRCFKRHGAEVIDTPVFELKETLTGKYGEDSKLIYDLKDQGGELLSLRYDLTVPF 135
           VF  II+CFKRHGAE IDTPVFELKETLTGKYGEDSKLIYDL DQGGE+ SLRYDLTVPF
Sbjct: 2   VFAKIIQCFKRHGAETIDTPVFELKETLTGKYGEDSKLIYDLADQGGEIASLRYDLTVPF 181

Query: 136 ARYLAMNKLTNIKRYHIAKVYRRDNPAMTRGRYREFYQCDFDIAGQFDPMIPDAECLKIM 195
           ARYLAMNK+TNIKRYHIAKVYRRDNPAMT+GRYREFYQCDFDIAGQ+DPM+PDAEC+K++
Sbjct: 182 ARYLAMNKVTNIKRYHIAKVYRRDNPAMTKGRYREFYQCDFDIAGQYDPMLPDAECVKLV 361

Query: 196 CEILSSLQIGNFLVKVNDRRILDGMFAVCGVPDSKFRTICSSVDKLDKVSWEEVKNEMVG 255
            EI+SSL IG+F+VKVN RR+LDGMFA CGVPD KFR ICS+VDKLDK  WE+V+ EMV 
Sbjct: 362 AEIMSSLNIGDFVVKVNHRRLLDGMFAACGVPDGKFRPICSAVDKLDKSPWEDVRXEMVE 541

Query: 256 EKGLAPEVADRIGDYVQQHGGVSLVEQLLQDPKLSQNKQAV 296
           EKGL P  ADRIG+YV+  GG  L + LL+DP L + K AV
Sbjct: 542 EKGLDPAAADRIGEYVRLQGGSELADDLLRDPNLQKQKSAV 664
>12536
          Length = 495

 Score = 32.7 bits (73), Expect(2) = 0.002,   Method: Compositional matrix adjust.
 Identities = 15/18 (83%), Positives = 16/18 (88%)
 Frame = -3

Query: 422 EERLKLVSELWDAGIKAE 439
           EERLKL +ELWDA IKAE
Sbjct: 493 EERLKLCAELWDADIKAE 440

 Score = 26.2 bits (56), Expect(2) = 0.002,   Method: Composition-based stats.
 Identities = 10/18 (55%), Positives = 11/18 (61%)
 Frame = -2

Query: 442 YKKNPKLLNQLQYWEEAG 459
           YK+NPK L Q QY E   
Sbjct: 434 YKRNPKALTQFQYCERGA 381
>20113
          Length = 1344

 Score = 29.3 bits (64), Expect = 4.3,   Method: Compositional matrix adjust.
 Identities = 12/32 (37%), Positives = 17/32 (53%)
 Frame = +3

Query: 220 MFAVCGVPDSKFRTICSSVDKLDKVSWEEVKN 251
           MF  C + + +FRT+CS + K     W  V N
Sbjct: 24  MFYFC*ISNERFRTLCSQISKSFV*RWRTVCN 119
>30183
          Length = 463

 Score = 28.9 bits (63), Expect = 5.1,   Method: Compositional matrix adjust.
 Identities = 12/31 (38%), Positives = 21/31 (67%)
 Frame = -1

Query: 263 VADRIGDYVQQHGGVSLVEQLLQDPKLSQNK 293
           V D +GD+ +QH G S + Q ++D K+S ++
Sbjct: 361 VLDNMGDWCKQHHGQSGLTQAVRDSKISASE 269
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6679995|ref|NP_032142.1| gamma-glutamyltransferase 1
[Mus musculus]
         (568 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

10880                                                                 372   e-103
28633                                                                 135   6e-32
28479                                                                  53   3e-07
>10880
          Length = 1352

 Score =  372 bits (954), Expect = e-103,   Method: Compositional matrix adjust.
 Identities = 206/450 (45%), Positives = 279/450 (62%), Gaps = 4/450 (0%)
 Frame = -1

Query: 107  EVAPRLANTTMF-NNSKDSEEGGLSVAVPGEIRGYELAHQRHGRLPWARLFQPSIQLARH 165
            E AP  A   M+  N   S  GGL+VA+PG+++G    HQR+G + W  L QPSI L   
Sbjct: 1352 ETAPAAATADMYVANMTLSTLGGLAVAIPGQLKGLWTLHQRYGSVAWRDLVQPSIDLCTD 1173

Query: 166  GFPVGKGLAIALDKKRDVIEKTPALCEVFCRQGKVLQEGETVTMPKLADTLQILAQEGAK 225
            G P+ + L     +  DV+   P     F   GKV   G  +  PKLA TL+++A +G  
Sbjct: 1172 GVPLSEALRERAIQYYDVLRDDPEYSMFFDGDGKVPALGTKLQRPKLAATLRVVADQGVH 993

Query: 226  AFYNGSLTAQIVKDIQEAGGIMTVEDLNNYRAELIEHPMSIGL--GDATLYVPSAPLSGP 283
            AFYNGSLT  IV DI+ AGGI+T  DL +Y+ ++ + P++  L     TL+    P SG 
Sbjct: 992  AFYNGSLTDNIVADIRGAGGIITRADLEDYQVDMPD-PVTFNLTHDGLTLFSMPPPGSGV 816

Query: 284  VLILILNILKGYNFSPKSVATPEQKALTYHRIVEAFRFAYAKRTMLGDPKFVDVSQVIRN 343
            VL  ILNIL GY F+  SV   E   LTYHRIVEA +FAYAKRT LGD + V+V++++ N
Sbjct: 815  VLEYILNILSGYRFNEDSVKK-EHAVLTYHRIVEAMKFAYAKRTQLGDMRVVNVTELVAN 639

Query: 344  MSSEFYATQLRARITDETTHPAAYYEPEFYLQDDGGTAHLSAVSEDGSAVAATSTINLYF 403
            M+S     ++R+ ITD  T   AYY P F    D GT+H+S V   G+AV+ TSTIN  F
Sbjct: 638  MTSSEKGEEIRSMITDSMTXDLAYYGPAFSDVTDAGTSHISVVDGSGNAVSITSTINTSF 459

Query: 404  GSKVLSRVSGILFNDEMDDFSSPNFINQFRVAPSPANFIKPGKQPLSSMCPSIILDKD-G 462
            GSKV    +GI+FN+EMDDFS+PN  N + V  SP NFI PGK+P+SSM P++ +D + G
Sbjct: 458  GSKVKGSRTGIIFNNEMDDFSTPNTTNFYGVPASPTNFIAPGKRPMSSMSPTVAVDXNSG 279

Query: 463  QVRMVVGASGGTQITTSVALAIINSLWFGYDVKRAVEEPRLHNQLLPNTTTVEKDIDQVV 522
             V +V+GA+GGT ITTSVAL  +++LWF  DV  A++ PR+H+QLLP   T+E    + +
Sbjct: 278  DVELVLGAAGGTMITTSVALVTMDTLWFKMDVPEAIDAPRIHHQLLPPEITMEDGFPEYI 99

Query: 523  TAGLKIRHHHTEVTPTFIAVVQAVVRASGG 552
              GLK +  H+   P + +VV A+ R + G
Sbjct: 98   REGLK-QKGHSVTAPXWKSVVTAIHRTADG 12
>28633
          Length = 459

 Score =  135 bits (339), Expect = 6e-32,   Method: Compositional matrix adjust.
 Identities = 68/149 (45%), Positives = 95/149 (63%), Gaps = 1/149 (0%)
 Frame = -3

Query: 263 PMSIGLGDA-TLYVPSAPLSGPVLILILNILKGYNFSPKSVATPEQKALTYHRIVEAFRF 321
           P+ + L D  T++ P  P SG VL  +LN+L GYN +   +   +    T HRIVE F+F
Sbjct: 457 PIQVTLDDGLTVFSPPPPSSGAVLSFMLNVLDGYNMTSXDLDGADNSVRTLHRIVETFKF 278

Query: 322 AYAKRTMLGDPKFVDVSQVIRNMSSEFYATQLRARITDETTHPAAYYEPEFYLQDDGGTA 381
           AYA RT LGD  F +V++V+ N++S  +A  +R++ITD  TH  +YY P  Y +   GTA
Sbjct: 277 AYAIRTDLGDEDFYNVTEVVXNLTSRNFANYIRSKITDNMTHNVSYYGPTIYDRYTTGTA 98

Query: 382 HLSAVSEDGSAVAATSTINLYFGSKVLSR 410
           H+S V ++G+AV+ATSTIN  FGSK   R
Sbjct: 97  HISIVDDEGNAVSATSTINTKFGSKRRGR 11
>28479
          Length = 399

 Score = 53.1 bits (126), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 34/110 (30%), Positives = 54/110 (49%), Gaps = 10/110 (9%)
 Frame = +1

Query: 469 GASGGTQITTSVALAIINSLWFGYDVKRAVEEPRLHNQLLPNTTTVEKDIDQVVTAG--- 525
           GAS  T+I T V   ++N   F  ++K A++ PRLH QL P   T  +D+      G   
Sbjct: 4   GASNATRIITGVVETLVNMFIFDMNLKEAIDFPRLHQQLYPTDHTEYEDVASAPVPGGKD 183

Query: 526 ------LKIRHHHTEV-TPTFIAVVQAVVRASGGWAAASDSRKGGEPAGY 568
                 +K     T V  P  ++ V ++++ +   +A +D RKGG+ A Y
Sbjct: 184 VFPLDVVKALTSQTMVPVPEGLSCVNSIMKINDNVSAIADWRKGGKSAFY 333
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|124339829|ref|NP_034609.2| heat shock 70kDa protein
1A [Mus musculus]
         (641 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

30255                                                                 284   e-102
21024                                                                 216   3e-56
37715                                                                 145   6e-55
27378                                                                 202   2e-52
26390                                                                 157   2e-38
24750                                                                 136   3e-32
06909                                                                  86   2e-21
31218                                                                  92   5e-19
09881                                                                  87   3e-17
20979                                                                  87   3e-17
12271                                                                  61   1e-09
13684                                                                  55   7e-08
03996                                                                  54   2e-07
13300                                                                  45   8e-05
34036                                                                  34   0.039
02981                                                                  30   2.6  
>30255
          Length = 1761

 Score =  284 bits (727), Expect(2) = e-102,   Method: Compositional matrix adjust.
 Identities = 142/199 (71%), Positives = 154/199 (77%)
 Frame = -1

Query: 328  KAQIHDLVLVGGSTRIPKVQKLLQDFFNGRDLNKSINPDEXXXXXXXXXXXILMGDKSEN 387
            K  IH++VLVGGSTRIPK+QKLLQDFFNG++L KSINPDE           IL GDKSE 
Sbjct: 1644 KPGIHEIVLVGGSTRIPKIQKLLQDFFNGKELCKSINPDEAVAYGACVQAAILHGDKSEE 1465

Query: 388  VQDXXXXXXXXXXXXXETAGGVMTALIKRNSXXXXXXXXXXXXYSDNQPGVLIQVYEGER 447
            VQD             ETAGGVMTALIKRN+            YSDNQPGVLIQVYEGER
Sbjct: 1464 VQDLLLLDVAPLSMGIETAGGVMTALIKRNTTIPTKQTQTFTTYSDNQPGVLIQVYEGER 1285

Query: 448  AMTRDNNLLGRFELSGIPPAPRGVPQIEVTFDIDANGILNVTATDKSTGKANKITITNDK 507
            AMTRDNNLLG+FEL+GIPPAPRGVPQIEVTFDIDANGILNV+A DKSTGK NKITITNDK
Sbjct: 1284 AMTRDNNLLGKFELTGIPPAPRGVPQIEVTFDIDANGILNVSAADKSTGKENKITITNDK 1105

Query: 508  GRLSKEEIERMVQEAERYK 526
            GRLSKEEIERMV +AE+ +
Sbjct: 1104 GRLSKEEIERMVNDAEKSR 1048

 Score =  106 bits (264), Expect(2) = e-102,   Method: Compositional matrix adjust.
 Identities = 46/78 (58%), Positives = 66/78 (84%)
 Frame = -3

Query: 534  DRVAAKNALESYAFNMKSAVEDEGLKGKLSEADKKKVLDKCQEVISWLDSNTLADKEEFV 593
            +R+++KN+LESYAF+MKS +EDE +K K+ E DKK ++DKC EVISWLD+N  A+K+E+ 
Sbjct: 1027 NRISSKNSLESYAFHMKSTIEDEKIKDKIGEEDKKTIVDKCNEVISWLDANQTAEKDEYD 848

Query: 594  HKREELERVCSPIISGLY 611
             K++ELE+VC+PII+ LY
Sbjct: 847  DKQKELEKVCNPIITKLY 794
>21024
          Length = 3220

 Score =  216 bits (549), Expect = 3e-56,   Method: Compositional matrix adjust.
 Identities = 156/422 (36%), Positives = 222/422 (52%), Gaps = 6/422 (1%)
 Frame = +1

Query: 166  GLNVLRIINEPTAAAIAYGLDRTGKGERNVLIFDLGGGTFDVSILTIDDGIFEVKATAGD 225
            G NVLR+INEPTAAA+A    +  +   + + F       DV  L + D    V +    
Sbjct: 727  G*NVLRVINEPTAAALALWHGQV*R*SDSGV*FR----RRDV*HLYLGDPEGSV*SQINQ 894

Query: 226  T-HLGGE-DFDNRLVSHFVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQASLE 283
              H+ G         S    +  RK K   SQ  + + R     +++K  LSSS Q  + 
Sbjct: 895  RRHIPGRRGLLTTTWSTSWHQNLRKSKD*TSQRIQWLCRDYVRQQKSKIELSSSLQTDIN 1074

Query: 284  IDSLFEGID----FYTSITRARFEELCSDLFRGTLEPVEKALRDAKMDKAQIHDLVLVGG 339
            +  L             ++R++FE L   L + T+ P +KAL+DA++ K+ I +++LVGG
Sbjct: 1075 LPYLTMDASGPKHMNLKLSRSKFESLVESLVKRTVGPCQKALQDAEVKKSDIGEVILVGG 1254

Query: 340  STRIPKVQKLLQDFFNGRDLNKSINPDEXXXXXXXXXXXILMGDKSENVQDXXXXXXXXX 399
             +R+PKVQ  +QD F GR  +KS+NPDE           +L GD    V D         
Sbjct: 1255 MSRMPKVQSTVQDLF-GRTPSKSVNPDEAVAIGAAIQGGVLAGD----VTDVLLLDVTPL 1419

Query: 400  XXXXETAGGVMTALIKRNSXXXXXXXXXXXXYSDNQPGVLIQVYEGERAMTRDNNLLGRF 459
                ET GGV T LI RN+             +D Q  V I+V++GER M  DN LLG+F
Sbjct: 1420 SLGIETLGGVFTKLINRNTTIPTKKSQVFSTAADGQTQVEIKVHQGEREMANDNKLLGQF 1599

Query: 460  ELSGIPPAPRGVPQIEVTFDIDANGILNVTATDKSTGKANKITITNDKGRLSKEEIERMV 519
             L GIPPAPRGVPQ+EVTFDIDANGI+NV+A DK TGK  +I I +  G LSK+EIE M+
Sbjct: 1600 TLVGIPPAPRGVPQVEVTFDIDANGIVNVSARDKGTGKEQQIVIQSSGG-LSKDEIENMI 1776

Query: 520  QEAERYKAEDEVQRDRVAAKNALESYAFNMKSAVEDEGLKGKLSEADKKKVLDKCQEVIS 579
            + AE +  +D  +++ V   N  +S   + +S +E+   K +L + +  K+ +K  EV  
Sbjct: 1777 KNAEAHAEDDRRKKELVEVLNQADSIIHDTESKMEE--FKDQLPQEECDKLREKINEVKQ 1950

Query: 580  WL 581
             L
Sbjct: 1951 LL 1956

 Score =  177 bits (450), Expect = 8e-45,   Method: Compositional matrix adjust.
 Identities = 108/271 (39%), Positives = 159/271 (58%), Gaps = 4/271 (1%)
 Frame = +3

Query: 3   KNTAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFT-DTERLIGDAAKNQVAL 61
           K   IGIDLGTT SCV + +  + +++ N +G+RTTPS +AFT D ER+ G  AK Q   
Sbjct: 243 KGHVIGIDLGTTNSCVALMEGKQAKVLENSEGSRTTPSVIAFTKDGERISGMPAKRQAVT 422

Query: 62  NPQNTVFDAKRLIGRKFGDAVVQSDMKHWPFQVV--NDGDKPKVQVNYKGESRSFFPEEI 119
           N +NT+   KRLIGR+F D  VQ DMK+  +++V  ++GD        + + + + P ++
Sbjct: 423 NAENTLSATKRLIGRRFEDPEVQKDMKNVSYKIVKASNGD-----AWVEAQGKMYSPSQV 587

Query: 120 SSMVLTKMKEIAEAYLGHPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAA 179
            + VL KMKE AE+YLG  V NAV+TVPAYFNDSQRQATKDAG I+GL  +       + 
Sbjct: 588 GAFVLMKMKETAESYLGSKVNNAVVTVPAYFNDSQRQATKDAGQISGLKCVACDQRTHSC 767

Query: 180 AIAYGLDRTGKGERNVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGE-DFDNRLV 238
           +  +    + K +    +    G    +S  +  + +   + T  +TH   E  FDN +V
Sbjct: 768 SSCFMAWTSLKIK**RCLI*AEGRLTSLSWRSRRECLKSNQPT--ETHSWEERTFDNYMV 941

Query: 239 SHFVEEFKRKHKKDISQNKRAVRRLRTACER 269
           +    EFK++   DI+++  AV+RLR A E+
Sbjct: 942 NFLASEFKKEQGLDITKDPMAVQRLREAAEK 1034
>37715
          Length = 468

 Score =  145 bits (367), Expect(2) = 6e-55,   Method: Compositional matrix adjust.
 Identities = 66/96 (68%), Positives = 81/96 (84%)
 Frame = -2

Query: 92  FQVVNDGDKPKVQVNYKGESRSFFPEEISSMVLTKMKEIAEAYLGHPVTNAVITVPAYFN 151
            +V+N  +KP +Q    G +++F PEEIS+MVL KM++IAEAYLG  + NAV+TVPAYFN
Sbjct: 458 LKVINKSNKPHIQALVSGATKTFAPEEISAMVLGKMRDIAEAYLGKKIDNAVVTVPAYFN 279

Query: 152 DSQRQATKDAGVIAGLNVLRIINEPTAAAIAYGLDR 187
           D+QRQATKDAG IAGLNV+RIINEPTAAAIAYGLD+
Sbjct: 278 DAQRQATKDAGTIAGLNVMRIINEPTAAAIAYGLDK 171

 Score = 87.8 bits (216), Expect(2) = 6e-55,   Method: Composition-based stats.
 Identities = 37/52 (71%), Positives = 47/52 (90%)
 Frame = -1

Query: 194 NVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLVSHFVEEF 245
           N+L+FDLGGGTFDVS+LTID+G+FEV AT GDTHLGGEDFD R++ HF++ +
Sbjct: 156 NILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMDHFIKLY 1
>27378
          Length = 410

 Score =  202 bits (515), Expect = 2e-52,   Method: Compositional matrix adjust.
 Identities = 96/124 (77%), Positives = 108/124 (87%)
 Frame = -1

Query: 244 EFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQASLEIDSLFEGIDFYTSITRARFE 303
           EFKRK+KKD+  N RA+RRLRTA ERAKRTLSSST+A++E+D+LFEG DFYT I+RARFE
Sbjct: 410 EFKRKYKKDLRSNPRALRRLRTAAERAKRTLSSSTEATIEVDALFEGHDFYTKISRARFE 231

Query: 304 ELCSDLFRGTLEPVEKALRDAKMDKAQIHDLVLVGGSTRIPKVQKLLQDFFNGRDLNKSI 363
           ELC+DLFR TL PVEKAL DAKMDK  IHD+VLVGGSTRIPKVQ LLQ FF G+ LN SI
Sbjct: 230 ELCADLFRQTLAPVEKALNDAKMDKQMIHDIVLVGGSTRIPKVQNLLQQFFGGKSLNLSI 51

Query: 364 NPDE 367
           NPDE
Sbjct: 50  NPDE 39
>26390
          Length = 665

 Score =  157 bits (396), Expect = 2e-38,   Method: Compositional matrix adjust.
 Identities = 85/181 (46%), Positives = 109/181 (60%), Gaps = 6/181 (3%)
 Frame = +2

Query: 404 ETAGGVMTALIKRNSXXXXXXXXXXXXYSDNQPGVLIQVYEGERAMTRDNNLLGRFELSG 463
           ET GGVMT LI R +              DNQ  V IQVYEGER+ T+DN+LLGRF+L+G
Sbjct: 56  ETVGGVMTTLIARGTTIPARKAKVFSTAQDNQDSVTIQVYEGERSRTKDNHLLGRFDLTG 235

Query: 464 IPPAPRGVPQIEVTFDIDANGILNVTATDKSTGKANKITITNDKGRLSKEEIERMVQEAE 523
           IP APRGVPQIEVTF +DANG++ V+A DK TG+ N I I      LS E++ERMVQEA+
Sbjct: 236 IPAAPRGVPQIEVTFQVDANGVMQVSAEDKGTGQKNDIIIQQSGSGLSPEDVERMVQEAQ 415

Query: 524 RYKAEDEVQRDRVAAKNALESYAFNMKSAVED------EGLKGKLSEADKKKVLDKCQEV 577
            +  ED   R+   ++  LES A+  +  ++D          G LS+ D    L   QEV
Sbjct: 416 DFAEEDRKFRELTESRTGLESLAYTAQHQLQDLHKMXASERPGTLSDDD----LHXAQEV 583

Query: 578 I 578
           +
Sbjct: 584 V 586
>24750
          Length = 552

 Score =  136 bits (342), Expect = 3e-32,   Method: Compositional matrix adjust.
 Identities = 63/71 (88%), Positives = 69/71 (97%)
 Frame = +1

Query: 439 LIQVYEGERAMTRDNNLLGRFELSGIPPAPRGVPQIEVTFDIDANGILNVTATDKSTGKA 498
           ++QVYEGERAMTRDNNLLG+FEL+GIPPAPRGVPQIEVTFDIDANGILNV+A DKSTGK 
Sbjct: 154 MLQVYEGERAMTRDNNLLGKFELTGIPPAPRGVPQIEVTFDIDANGILNVSAADKSTGKE 333

Query: 499 NKITITNDKGR 509
           NKITITNDKG+
Sbjct: 334 NKITITNDKGQ 366
>06909
          Length = 456

 Score = 86.3 bits (212), Expect(2) = 2e-21,   Method: Compositional matrix adjust.
 Identities = 37/65 (56%), Positives = 53/65 (81%)
 Frame = -3

Query: 547 FNMKSAVEDEGLKGKLSEADKKKVLDKCQEVISWLDSNTLADKEEFVHKREELERVCSPI 606
            +MKS +EDE +K K+S  DKK +LDKC EVI+WLD+N LA+K+E+  K++E+E+VC+PI
Sbjct: 388 LHMKSTIEDEKIKDKISTEDKKTILDKCDEVIAWLDANQLAEKDEYDDKQKEIEKVCNPI 209

Query: 607 ISGLY 611
           I+ LY
Sbjct: 208 ITKLY 194

 Score = 34.7 bits (78), Expect(2) = 2e-21,   Method: Compositional matrix adjust.
 Identities = 14/23 (60%), Positives = 20/23 (86%)
 Frame = -1

Query: 524 RYKAEDEVQRDRVAAKNALESYA 546
           +YK +DE Q+ R++AKN+LESYA
Sbjct: 456 KYKEDDEKQKSRISAKNSLESYA 388
>31218
          Length = 322

 Score = 92.4 bits (228), Expect = 5e-19,   Method: Compositional matrix adjust.
 Identities = 48/100 (48%), Positives = 68/100 (68%)
 Frame = +2

Query: 225 DTHLGGEDFDNRLVSHFVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQASLEI 284
           DTHLGGEDFD RLV + V+  K+K  +D+  + RA+ RLR + E+AKR LSS     +++
Sbjct: 2   DTHLGGEDFDQRLVDYLVKLIKQKTGRDVRHDTRAMSRLRRSAEKAKRALSSQHSTKVDL 181

Query: 285 DSLFEGIDFYTSITRARFEELCSDLFRGTLEPVEKALRDA 324
           D +   +   T +TRA+FEEL +DLFR TL  V++AL D+
Sbjct: 182 DGVTSDLADLT-LTRAKFEELNTDLFRSTLTTVKRALEDS 298
>09881
          Length = 600

 Score = 86.7 bits (213), Expect = 3e-17,   Method: Composition-based stats.
 Identities = 42/106 (39%), Positives = 64/106 (60%)
 Frame = +3

Query: 3   KNTAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVALN 62
           K  A G+ LGT  +C+ V++ GK  + AND G+R+TP  VAFT  +  +G +AK  +  N
Sbjct: 177 KMAAYGVHLGTCSACLAVYKDGKTSVAANDAGDRSTPCVVAFTACDAEVGASAKQGIVSN 356

Query: 63  PQNTVFDAKRLIGRKFGDAVVQSDMKHWPFQVVNDGDKPKVQVNYK 108
            +NTV + KR++G  F D V Q  +   P +VVN  ++P  +V +K
Sbjct: 357 VKNTVCNVKRILGLTFEDPVTQEYLASSPVKVVNQKNQPMFEVEFK 494

 Score = 47.8 bits (112), Expect = 1e-05,   Method: Composition-based stats.
 Identities = 26/53 (49%), Positives = 35/53 (66%)
 Frame = +2

Query: 136 GHPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAYGLDRT 188
           G  + +AV+ VP+ F+D QR A   A   AG  VLR+INE +AAA+AY L +T
Sbjct: 2   GKGIQDAVLAVPSDFSDKQRAAASAAASKAGFKVLRLINECSAAALAYDLGQT 160
>20979
          Length = 976

 Score = 86.7 bits (213), Expect = 3e-17,   Method: Compositional matrix adjust.
 Identities = 47/140 (33%), Positives = 79/140 (56%), Gaps = 2/140 (1%)
 Frame = +1

Query: 230 GEDFDNRLVSHFVEEFKRKHKKD--ISQNKRAVRRLRTACERAKRTLSSSTQASLEIDSL 287
           G +   RL  H  + F  + K+   +  N RA+ +L    ER K+ LS+++    +++ L
Sbjct: 70  GVEMTLRLRDHLAKVFNGQKKRSFKLEDNPRAMAKLLKEAERVKKVLSANSDHKAQVEGL 249

Query: 288 FEGIDFYTSITRARFEELCSDLFRGTLEPVEKALRDAKMDKAQIHDLVLVGGSTRIPKVQ 347
            EG DF   ++R  + EL  DL     +P+E AL+ +++   +I +++L+GG +R+P+VQ
Sbjct: 250 VEGEDFAAKVSREDYLELIKDLLARVTKPMEDALKVSEITMPEITEIILMGGGSRVPRVQ 429

Query: 348 KLLQDFFNGRDLNKSINPDE 367
           + L  F    DL KSIN DE
Sbjct: 430 EELLKFSGKSDLGKSINTDE 489
>12271
          Length = 1762

 Score = 61.2 bits (147), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 26/76 (34%), Positives = 48/76 (63%)
 Frame = +2

Query: 292 DFYTSITRARFEELCSDLFRGTLEPVEKALRDAKMDKAQIHDLVLVGGSTRIPKVQKLLQ 351
           DF   +TR ++  L  DL      PV++ L  +++  A+I +++L+GG +R+PK+ ++L 
Sbjct: 41  DFSCKVTRDKYLHLIQDLLDRVTLPVQQVLTASQITWAEITEIILMGGGSRLPKIHEILL 220

Query: 352 DFFNGRDLNKSINPDE 367
           D+   ++L KS+N DE
Sbjct: 221 DYSGKKELGKSLNTDE 268

 Score = 30.4 bits (67), Expect = 2.5,   Method: Compositional matrix adjust.
 Identities = 22/106 (20%), Positives = 48/106 (45%), Gaps = 1/106 (0%)
 Frame = +1

Query: 500  KITI-TNDKGRLSKEEIERMVQEAERYKAEDEVQRDRVAAKNALESYAFNMKSAVEDEGL 558
            K+T+   D   LSK+++++  +    ++  DE +     A+N +ES+    +  + +E  
Sbjct: 982  KVTVKVKDMAELSKDQVKQSKKRLTDWRKRDEEKAAVQKARNEVESFIITAQDKMSEETY 1161

Query: 559  KGKLSEADKKKVLDKCQEVISWLDSNTLADKEEFVHKREELERVCS 604
                ++ ++  +LD+  +   WL   +   K+ F     E    CS
Sbjct: 1162 LASSTDEERAXILDQLSQASDWLYEQSHQAKKWFSPTNTET*GTCS 1299
>13684
          Length = 438

 Score = 55.5 bits (132), Expect = 7e-08,   Method: Composition-based stats.
 Identities = 25/60 (41%), Positives = 37/60 (61%)
 Frame = -3

Query: 3   KNTAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVALN 62
           K  A G+ LGT  +C+ V++ GK  + AND G+R+TP  VAFT  +  +G +AK  +  N
Sbjct: 181 KMAAYGVHLGTCSACLAVYKDGKTSVAANDAGDRSTPCVVAFTACDAEVGASAKQGIVSN 2
>03996
          Length = 1105

 Score = 54.3 bits (129), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 26/64 (40%), Positives = 41/64 (64%)
 Frame = -2

Query: 304  ELCSDLFRGTLEPVEKALRDAKMDKAQIHDLVLVGGSTRIPKVQKLLQDFFNGRDLNKSI 363
            EL  DL     +P+E AL+ +++   +I +++L+GG +R+P+VQ+ L  F    DL KSI
Sbjct: 1056 ELIKDLLARVTKPMEDALKVSEITMPEITEIILMGGGSRVPRVQEELLKFSGKSDLGKSI 877

Query: 364  NPDE 367
            N DE
Sbjct: 876  NTDE 865
>13300
          Length = 453

 Score = 45.1 bits (105), Expect = 8e-05,   Method: Compositional matrix adjust.
 Identities = 34/149 (22%), Positives = 69/149 (46%), Gaps = 17/149 (11%)
 Frame = +3

Query: 154 QRQATKDAGVIAGLNVLRIINEPTAAAIAYGLDRT---GKGERNVLIFDLGGGTFDVSIL 210
           +R+A   A    G+NVL+++ +  A A+ YG+ R        +  + +D+G  +   +++
Sbjct: 3   ERRAIMTAADXVGINVLQLMTDSAAVALNYGVFRRKNFNTTAQYYMFYDMGATSTVATVV 182

Query: 211 T-----IDDGI-------FEVKATAGDTHLGGEDFDNRLVSHFVEEFKRKHKKD--ISQN 256
           +     + +G          +K    D  LGG +   RL  H  + F  + K+   +  N
Sbjct: 183 SYQVVKVKEGTRVESNPQLTIKGVGFDRTLGGLEMTLRLRDHLAKVFNGQKKRSFKLEDN 362

Query: 257 KRAVRRLRTACERAKRTLSSSTQASLEID 285
            RA+ +L    ER K+ LS+++    +++
Sbjct: 363 PRAMAKLLKEAERVKKVLSANSDHKAQVE 449
>34036
          Length = 363

 Score = 33.9 bits (76), Expect(2) = 0.039,   Method: Composition-based stats.
 Identities = 12/24 (50%), Positives = 21/24 (87%)
 Frame = +2

Query: 588 DKEEFVHKREELERVCSPIISGLY 611
           +K+E+  K++E+E+VC+PII+ LY
Sbjct: 2   EKDEYDDKQKEIEKVCNPIITKLY 73

 Score = 21.6 bits (44), Expect(2) = 0.039,   Method: Composition-based stats.
 Identities = 8/9 (88%), Positives = 9/9 (100%)
 Frame = +1

Query: 633 SGPTIEEVD 641
           +GPTIEEVD
Sbjct: 151 AGPTIEEVD 177
>02981
          Length = 1736

 Score = 30.4 bits (67), Expect = 2.6,   Method: Compositional matrix adjust.
 Identities = 22/33 (66%), Positives = 25/33 (75%), Gaps = 1/33 (3%)
 Frame = -1

Query: 507  KGRLSKEEIERMVQ-EAERYKAEDEVQRDRVAA 538
            KGR+ KEE ER+ + EAER KAEDE QR R AA
Sbjct: 1055 KGRM-KEEAERLAEIEAERKKAEDE-QRAREAA 963
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|30519997|ref|NP_848760.1| bleomycin hydrolase [Mus
musculus]
         (455 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

19078                                                                 369   e-102
27397                                                                  33   0.33 
34509                                                                  33   0.34 
17854                                                                  29   3.9  
26028                                                                  29   4.8  
16373                                                                  28   6.3  
03747                                                                  28   6.8  
39186                                                                  28   6.9  
>19078
          Length = 872

 Score =  369 bits (946), Expect = e-102,   Method: Compositional matrix adjust.
 Identities = 164/286 (57%), Positives = 218/286 (76%)
 Frame = +2

Query: 65  TNQKSSGRCWIFSCLNVMRLPFMKKFNIEEFEFSQSYLFFWDKVERCYFFLNAFVDTAQK 124
           TNQ+SSGRCW+F+ LN +RLPFMK +N++EFEFSQ++LF+WDK+ERC +FLN  V TA++
Sbjct: 2   TNQRSSGRCWLFAALNCIRLPFMKNYNLDEFEFSQAFLFYWDKIERCNYFLNNIVKTAKR 181

Query: 125 KEPEDGRLVQYLLMNPTNDGGQWDMLVNIVEKYGVVPKKCFPESHTTEATRRMNDILNHK 184
            E  DGRLV +LL++PT+DGGQW MLVN++ K+G++PKKCFPES + E++ RMN IL  K
Sbjct: 182 GEEVDGRLVSFLLLDPTSDGGQWHMLVNLITKHGLMPKKCFPESFSCESSIRMNAILKSK 361

Query: 185 MREFCIRLRNLVHSGATKGEISSTQDAMMEEIFRVVCICLGNPPETFTWEYRDKDKNYHK 244
           +RE+   LR L+    +  EI+S     M EI++VV ICLG P ETFTWEY DK KN+  
Sbjct: 362 LREYARNLRELLEKKPSDEEITSKIQEQMAEIYKVVGICLGIPAETFTWEYYDKSKNFQS 541

Query: 245 IGPITPLQFYKEHVKPLFNMEDKICFVNDPRPQHKYNKLYTVDYLSNMVGGRKTLYNNQP 304
           IGPI+ L+FY+ +VKP FN+EDK+C V DPRP  +Y+++YTVD L N+VGGR  LYNNQ 
Sbjct: 542 IGPISSLEFYENYVKPHFNVEDKVCLVTDPRPTSRYDQVYTVDCLGNVVGGRPVLYNNQN 721

Query: 305 IDFLKKMVAASIKDGEAVWFGCDVGKHFNGKLGLSDMNVYDHELVF 350
           +D L  MV  S++ GEAVWFGC+V K F  K G+ DM+V++ +LV 
Sbjct: 722 VDLLLAMVTKSLQAGEAVWFGCEVSKRFASKQGIEDMDVHNFKLVL 859
>27397
          Length = 375

 Score = 32.7 bits (73), Expect = 0.33,   Method: Composition-based stats.
 Identities = 11/33 (33%), Positives = 22/33 (66%)
 Frame = -2

Query: 74  WIFSCLNVMRLPFMKKFNIEEFEFSQSYLFFWD 106
           +IF C++V+ + FM  F    F+F++++  FW+
Sbjct: 146 YIFVCVSVLSIQFMVFFGGNNFDFNRTFFSFWN 48
>34509
          Length = 408

 Score = 32.7 bits (73), Expect = 0.34,   Method: Composition-based stats.
 Identities = 16/55 (29%), Positives = 25/55 (45%)
 Frame = +1

Query: 362 RLAFGESLMTHAMTFTAVSEKDNQEGTFVKWRVENSWGEDHGHKGYLCMTDEWFS 416
           R++F  S+  H       +E D +E  F         GEDHG +  LC   +W++
Sbjct: 121 RVSFQRSIHRHCDGSAEAAEPDREEDMF--------QGEDHGPQALLCAPQQWYT 261
>17854
          Length = 759

 Score = 28.9 bits (63), Expect = 3.9,   Method: Compositional matrix adjust.
 Identities = 23/87 (26%), Positives = 43/87 (49%), Gaps = 3/87 (3%)
 Frame = +2

Query: 225 GNPPETFTWEYRDKDKNYHKIGPITPLQFY-KEHVKPLFNME--DKICFVNDPRPQHKYN 281
           G P +  + +    D +Y + G +  +++  K+ V  L  +   + +  V+  RP+ K  
Sbjct: 287 GLPEDLMSTDLXRGDMDYRRKGKMVAVRWRDKKDVNFLSTIHKPEMVEVVSRSRPERKRK 466

Query: 282 KLYTVDYLSNMVGGRKTLYNNQPIDFL 308
              TVDY++NM G     ++NQ I +L
Sbjct: 467 PTATVDYINNMAG---VNHSNQLISYL 538
>26028
          Length = 414

 Score = 28.9 bits (63), Expect = 4.8,   Method: Composition-based stats.
 Identities = 13/30 (43%), Positives = 16/30 (53%)
 Frame = -3

Query: 378 AVSEKDNQEGTFVKWRVENSWGEDHGHKGY 407
            VS+  N   T   W V+NSWG   G +GY
Sbjct: 199 GVSDYPNFHKTLPYWIVKNSWGPRWGEQGY 110
>16373
          Length = 996

 Score = 28.5 bits (62), Expect = 6.3,   Method: Compositional matrix adjust.
 Identities = 14/28 (50%), Positives = 16/28 (57%), Gaps = 3/28 (10%)
 Frame = -2

Query: 387 GTFVK---WRVENSWGEDHGHKGYLCMT 411
           GTF     W V+NSWG D G  GY+ M 
Sbjct: 575 GTFQSQQYWLVKNSWGVDWGMXGYIMMA 492
>03747
          Length = 1915

 Score = 28.1 bits (61), Expect = 6.8,   Method: Compositional matrix adjust.
 Identities = 14/42 (33%), Positives = 21/42 (50%)
 Frame = +3

Query: 370 MTHAMTFTAVSEKDNQEGTFVKWRVENSWGEDHGHKGYLCMT 411
           + H +       +D +E     W V+NSWG   G KGY+ M+
Sbjct: 276 LDHGVLAVGYGSEDGKE----FWLVKNSWGLSWGEKGYIKMS 389
>39186
          Length = 728

 Score = 28.1 bits (61), Expect = 6.9,   Method: Compositional matrix adjust.
 Identities = 10/20 (50%), Positives = 13/20 (65%)
 Frame = -1

Query: 392 WRVENSWGEDHGHKGYLCMT 411
           W V+NSWG D G  GY+ + 
Sbjct: 533 WIVKNSWGTDWGMNGYILIA 474
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|33563256|ref|NP_034436.1| guanine nucleotide binding
protein (G protein), alpha inhibiting 3 [Mus musculus]
         (354 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

11965                                                                 367   e-102
13527                                                                 235   2e-62
29196                                                                 141   4e-34
20516                                                                 114   6e-26
34094                                                                  70   9e-13
08153                                                                  51   9e-07
09827                                                                  49   2e-06
10862                                                                  49   2e-06
18949                                                                  42   3e-04
11378                                                                  40   0.002
18208                                                                  32   0.44 
15546                                                                  32   0.50 
08297                                                                  30   1.3  
20750                                                                  30   1.3  
>11965
          Length = 3256

 Score =  367 bits (942), Expect = e-102,   Method: Compositional matrix adjust.
 Identities = 172/222 (77%), Positives = 191/222 (86%)
 Frame = +1

Query: 133 DGGVQACFSRSREYQLNDSASYYLNDLDRISQTNYIPTQQDVLRTRVKTTGIVETHFTFK 192
           D GVQ CFSRS EYQLNDSA Y+L+DLDR+   +Y+PT+QD+LRTRVKTTGIVE HF+FK
Sbjct: 1   DSGVQDCFSRSNEYQLNDSAKYFLDDLDRLGTKDYMPTEQDILRTRVKTTGIVEVHFSFK 180

Query: 193 ELYFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAEDEEMNRMHESMKLFDS 252
            L FK+FDVGGQRSERKKWIHCFE VTAIIFCVA+S+YD VL EDE  NRM ES+KLFDS
Sbjct: 181 NLNFKLFDVGGQRSERKKWIHCFEDVTAIIFCVAMSEYDQVLHEDETTNRMQESLKLFDS 360

Query: 253 ICNNKWFTDTSIILFLNKKDLFEEKIKRSPLTICYPEYTGSNTYEEAAAYIQCQFEDLNR 312
           ICNNKWFTDTSIILFLNKKDLFEEKIK+SPLT+C+PEYTG  TYEE AAYIQ QFE  N+
Sbjct: 361 ICNNKWFTDTSIILFLNKKDLFEEKIKKSPLTVCFPEYTGKQTYEEVAAYIQAQFEAKNK 540

Query: 313 RKDTKEVYTHFTCATDTKNVQFVFDAVTDVIIKNNLKECGLY 354
               KE+Y H TCATDT N+QFVFDAVTDVII NNL+ CGLY
Sbjct: 541 SSQ-KEIYCHQTCATDTNNIQFVFDAVTDVIIANNLRGCGLY 663
>13527
          Length = 1091

 Score =  235 bits (600), Expect = 2e-62,   Method: Compositional matrix adjust.
 Identities = 114/198 (57%), Positives = 145/198 (73%), Gaps = 1/198 (0%)
 Frame = -2

Query: 1    MGCTLSAEDKAAVERSKMIDRNLREDXXXXXXXXXXXXXXXXXSGKSTIVKQMKIIHEDG 60
            MGCTLSAE++AA+ERSK I++NL+ED                 SGKSTIVKQMKIIHE G
Sbjct: 1042 MGCTLSAEERAAMERSKAIEKNLKEDGMQAAKDIKLLLLGAGESGKSTIVKQMKIIHEGG 863

Query: 61   YSEDECKQYKVVVYSNTIQSIIAIIRAMGRLKIDFGESARADDARQLF-VLAGSAEEGVM 119
            ++ ++ KQY+ VV+SNTIQS++AIIRAMG L I FG++ R  DA+ +  V+A   +    
Sbjct: 862  FTSEDNKQYRPVVFSNTIQSLVAIIRAMGTLSIPFGDNERESDAKMVLDVIARMEDTEPF 683

Query: 120  TSELAGVIKRLWRDGGVQACFSRSREYQLNDSASYYLNDLDRISQTNYIPTQQDVLRTRV 179
            + EL   ++RLW D GVQ CFSRS EYQLNDSA Y+L+DLDR+   +Y+PT+QD+LRTRV
Sbjct: 682  SEELLAAMERLWMDSGVQDCFSRSNEYQLNDSAKYFLDDLDRLGTKDYMPTEQDILRTRV 503

Query: 180  KTTGIVETHFTFKELYFK 197
            KTTGIVE HF+FK L FK
Sbjct: 502  KTTGIVEVHFSFKNLNFK 449
>29196
          Length = 431

 Score =  141 bits (356), Expect = 4e-34,   Method: Compositional matrix adjust.
 Identities = 83/149 (55%), Positives = 93/149 (62%), Gaps = 6/149 (4%)
 Frame = -2

Query: 125 GVIKRLWRDGGVQACFSRSRE-----YQLNDSASYYLNDLDRI-SQTNYIPTQQDVLRTR 178
             +KRLW D GVQ C SR+         LN S    +    RI SQ N     +      
Sbjct: 430 AAMKRLWLDSGVQEC-SRAATNTN*TIPLNISWMI*IG*ALRITSQPN-----RTFCAPE 269

Query: 179 VKTTGIVETHFTFKELYFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAEDE 238
            +   +       K L FK+FDVGGQRSERKKWIHCFE VTAIIFCVA+S+YD VL EDE
Sbjct: 268 SRPPAL*RFISPLKNLNFKLFDVGGQRSERKKWIHCFEDVTAIIFCVAMSEYDQVLHEDE 89

Query: 239 EMNRMHESMKLFDSICNNKWFTDTSIILF 267
             NRM ES+KLFDSICNNKWFTDTSIILF
Sbjct: 88  TTNRMQESLKLFDSICNNKWFTDTSIILF 2
>20516
          Length = 534

 Score =  114 bits (285), Expect = 6e-26,   Method: Compositional matrix adjust.
 Identities = 63/162 (38%), Positives = 95/162 (58%), Gaps = 1/162 (0%)
 Frame = +2

Query: 190 TFKELYFKMFDV-GGQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAEDEEMNRMHESMK 248
           TF+ ++F + +V GGQRS+R+KW  CF G+T+I+F  A S++D VL ED + NR+ ES  
Sbjct: 41  TFRNIFFLVGEVTGGQRSQRQKWYQCFVGITSILFLAASSEFDQVLMEDRKTNRLQESCD 220

Query: 249 LFDSICNNKWFTDTSIILFLNKKDLFEEKIKRSPLTICYPEYTGSNTYEEAAAYIQCQFE 308
           +F++I NNK F+  SIILFLNK DL ++K     L   +  ++G +     +  I     
Sbjct: 221 IFETIINNKSFSGVSIILFLNKMDLLQDKN*ACQLRRLFSRFSG*SQGH*CSQSI*ASAV 400

Query: 309 DLNRRKDTKEVYTHFTCATDTKNVQFVFDAVTDVIIKNNLKE 350
                   +    HFT A DT+N++ VF  V D I+ +NL+ 
Sbjct: 401 *FAPT*SKQTFVHHFTTAIDTENIKHVFQDVKDTILHDNLRS 526
>34094
          Length = 452

 Score = 70.5 bits (171), Expect = 9e-13,   Method: Compositional matrix adjust.
 Identities = 31/48 (64%), Positives = 38/48 (79%)
 Frame = +1

Query: 54  KIIHEDGYSEDECKQYKVVVYSNTIQSIIAIIRAMGRLKIDFGESARA 101
           +IIHE GYS++EC QYK VVYSN IQS+IAI+RAM  L ++FG   RA
Sbjct: 103 RIIHEKGYSQEECLQYKPVVYSNAIQSMIAIVRAMNLLSVEFGHPDRA 246
>08153
          Length = 1703

 Score = 50.8 bits (120), Expect = 9e-07,   Method: Compositional matrix adjust.
 Identities = 41/151 (27%), Positives = 58/151 (38%)
 Frame = +1

Query: 177 TRVKTTGIVETHFTFKELYFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAE 236
           T + T G       +K + F ++DVGGQ   R  W H F+    +IF V  +D + +   
Sbjct: 163 TTIPTIGFNVETVEYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERINEA 342

Query: 237 DEEMNRMHESMKLFDSICNNKWFTDTSIILFLNKKDLFEEKIKRSPLTICYPEYTGSNTY 296
            EE+ RM     L D+I          I++F NK+DL                    N Y
Sbjct: 343 KEELARMLNEDDLRDAI----------ILVFANKQDL-------------------PNAY 435

Query: 297 EEAAAYIQCQFEDLNRRKDTKEVYTHFTCAT 327
             +         +L  RK     Y   TCAT
Sbjct: 436 SASEVTAHLGLANLKGRK----WYMQATCAT 516
>09827
          Length = 1201

 Score = 49.3 bits (116), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 30/97 (30%), Positives = 47/97 (48%)
 Frame = -3

Query: 177  TRVKTTGIVETHFTFKELYFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAE 236
            T + T G       +K + F ++DVGGQ   R  W H F+    +IF V  +D + V   
Sbjct: 1034 TTIPTIGFNVETVEYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDKERVQEA 855

Query: 237  DEEMNRMHESMKLFDSICNNKWFTDTSIILFLNKKDL 273
             EE+ RM    +L D++          +++F NK+DL
Sbjct: 854  REELTRMLNEDELRDAV----------LLVFANKQDL 774
>10862
          Length = 2896

 Score = 49.3 bits (116), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 27/83 (32%), Positives = 42/83 (50%)
 Frame = -3

Query: 191  FKELYFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAEDEEMNRMHESMKLF 250
             +E  F ++DVGGQ   R  W H + G   +IF V  +D D +    +E++R        
Sbjct: 2495 LQECQFNVWDVGGQDKIRPLWRHYYTGTQGLIFVVDCADRDRIDEARQELHR-------- 2340

Query: 251  DSICNNKWFTDTSIILFLNKKDL 273
              I N++   D  I++F NK+DL
Sbjct: 2339 --IINDREMRDAIILIFANKQDL 2277
>18949
          Length = 414

 Score = 42.4 bits (98), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 24/94 (25%), Positives = 41/94 (43%), Gaps = 1/94 (1%)
 Frame = +3

Query: 180 KTTGIVETH-FTFKELYFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAEDE 238
           + TG+  +   +   + F  FD+GG R  R+ W   F  V  I+F V + D +       
Sbjct: 12  RPTGLPTSEELSMGGMTFTTFDLGGHRQARRVWKDYFPAVDGIVFIVDVHDTE------- 170

Query: 239 EMNRMHESMKLFDSICNNKWFTDTSIILFLNKKD 272
              R+ E+    DS+  +    D  +++  NK D
Sbjct: 171 ---RITEAKAELDSLLRDDQIADIPVLVLGNKMD 263
>11378
          Length = 1688

 Score = 40.0 bits (92), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 28/115 (24%), Positives = 47/115 (40%), Gaps = 1/115 (0%)
 Frame = +3

Query: 159 LDRISQTNYIPT-QQDVLRTRVKTTGIVETHFTFKELYFKMFDVGGQRSERKKWIHCFEG 217
           LD   +T  +   + D +   V T        +   + F  FD+GG R  R+ W   F  
Sbjct: 345 LDNAGKTTLLHMLKDDKMAQHVPTLHPTSEELSMGGMRFTTFDLGGHRQARRVWKDYFPA 524

Query: 218 VTAIIFCVALSDYDLVLAEDEEMNRMHESMKLFDSICNNKWFTDTSIILFLNKKD 272
           V  I+F V + D +          R+ E+    DS+  ++   +  I++  NK D
Sbjct: 525 VDGIVFLVDVHDRE----------RLVEAKAELDSLMTDEQVANAPILVLGNKID 659
>18208
          Length = 458

 Score = 32.0 bits (71), Expect = 0.44,   Method: Compositional matrix adjust.
 Identities = 13/38 (34%), Positives = 20/38 (52%)
 Frame = -1

Query: 192 KELYFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSD 229
           K     ++D+GGQR  R  W + FE    +I+ +  SD
Sbjct: 176 KGFKLNVWDIGGQRRIRPYWKNYFENTDLLIYVIDSSD 63
>15546
          Length = 1563

 Score = 31.6 bits (70), Expect = 0.50,   Method: Compositional matrix adjust.
 Identities = 16/49 (32%), Positives = 28/49 (57%), Gaps = 2/49 (4%)
 Frame = +3

Query: 110 LAGSAEEGVMT-SELAGVIKRLWRDGGVQACFSRSRE-YQLNDSASYYL 156
           + G  EEG  + S+++GV+ R+W  G VQ  F  + + + L+D   + L
Sbjct: 24  IVGVTEEGAQSESQVSGVVSRIW-PGSVQVAFEENEDVFSLDDDKPFRL 167
>08297
          Length = 541

 Score = 30.4 bits (67), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 14/34 (41%), Positives = 19/34 (55%)
 Frame = +2

Query: 319 VYTHFTCATDTKNVQFVFDAVTDVIIKNNLKECG 352
           ++ HFTCAT  K   FV   +T +I+ N   E G
Sbjct: 5   IFHHFTCATPRKKSPFVVCFITQIILINYDHEAG 106
>20750
          Length = 541

 Score = 30.0 bits (66), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 19/58 (32%), Positives = 27/58 (46%)
 Frame = -2

Query: 122 ELAGVIKRLWRDGGVQACFSRSREYQLNDSASYYLNDLDRISQTNYIPTQQDVLRTRV 179
           E  G+IK +   G     +  S   QLN + +Y+L   D  S TN +P   D L+  V
Sbjct: 429 EKGGIIKTMENLGHKTLPYKMSMHGQLNSTGNYFLVHFD--SSTNALPDVHDELKRDV 262
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|33859640|ref|NP_035658.1| transaldolase 1 [Mus
musculus]
         (337 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

13340                                                                 214   e-102
09812                                                                  69   2e-12
06638                                                                  32   0.47 
38660                                                                  31   0.64 
>13340
          Length = 934

 Score =  214 bits (545), Expect(3) = e-102,   Method: Compositional matrix adjust.
 Identities = 98/146 (67%), Positives = 121/146 (82%)
 Frame = -1

Query: 69  GKKLGGPQEEQIKNAIDKLFVLFGAEILKKIPGRVSTEVDARLSFDKDAMVARARRLIEL 128
           G +  G +EEQ+ NA+DK+ + FG +IL+ IPGRVSTEVDARLSFDK+ MV +A++LIEL
Sbjct: 847 GPRKRGSEEEQLSNAMDKVCINFGRKILEIIPGRVSTEVDARLSFDKEGMVKKAKQLIEL 668

Query: 129 YKEAGVGKDRILIKLSSTWEGIQAGKELEEQHGIHCNMTLLFSFAQAVACAEAGVTLISP 188
           YK  GVGK+RILIKLSSTWEG+QA +ELE ++GIHCNMTL+F+F QA+AC EA  TLISP
Sbjct: 667 YKAEGVGKERILIKLSSTWEGVQAARELESKYGIHCNMTLIFNFHQAIACGEAKATLISP 488

Query: 189 FVGRILDWHVANTDKKSYEPQEDPGV 214
           FVGRI DW V N D+KS+EP +DPG 
Sbjct: 487 FVGRIFDWFVKNKDQKSFEPLDDPGC 410

 Score =  150 bits (378), Expect(3) = e-102,   Method: Compositional matrix adjust.
 Identities = 71/117 (60%), Positives = 88/117 (75%)
 Frame = -3

Query: 214 VKSVTKIYNYYKKFGYKTIVMGASFRNTGEIKALAGCDFLTISPKLLGELLKDNSKLAPA 273
           V+SVT IYNYYKKFGYKT+VMGASFRNTG+I  LAGCD LTISP LL +L +    +   
Sbjct: 413 VRSVTXIYNYYKKFGYKTVVMGASFRNTGQIMGLAGCDLLTISPGLLEKLSQSTDSVEVY 234

Query: 274 LSVKAAQTSDSEKIHLDEKAFRWLHNEDQMAVEKLSDGIRKFAADAIKLERMLTERM 330
           L+   A   D +++ +DEK FRW  NED+MA +KL++GIRKFA DA+KLE ML ER+
Sbjct: 233 LNKDKAADLDIDQVTVDEKVFRWQMNEDEMANDKLAEGIRKFAVDAVKLENMLKERL 63

 Score = 48.5 bits (114), Expect(3) = e-102,   Method: Compositional matrix adjust.
 Identities = 21/33 (63%), Positives = 26/33 (78%)
 Frame = -3

Query: 41  DATTNPSLILAAAQMPAYQELVEEAIAYGKKLG 73
           DATTNPSLI AA+ MPAYQ L++ AI + K+ G
Sbjct: 929 DATTNPSLIFAASSMPAYQSLIDNAIDWAKEKG 831
>09812
          Length = 400

 Score = 68.9 bits (167), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 31/56 (55%), Positives = 43/56 (76%)
 Frame = -2

Query: 44  TNPSLILAAAQMPAYQELVEEAIAYGKKLGGPQEEQIKNAIDKLFVLFGAEILKKI 99
           TNPSLI AA+ MPAYQ L++ AI + K+ GG +EEQ+ NA+DK+ + FG +IL+ I
Sbjct: 168 TNPSLIFAASSMPAYQSLIDNAIDWAKEKGGSEEEQLSNAMDKVCINFGRKILEII 1
>06638
          Length = 2408

 Score = 31.6 bits (70), Expect = 0.47,   Method: Compositional matrix adjust.
 Identities = 19/74 (25%), Positives = 31/74 (41%)
 Frame = +2

Query: 137 DRILIKLSSTWEGIQAGKELEEQHGIHCNMTLLFSFAQAVACAEAGVTLISPFVGRILDW 196
           D+I+++L S  E  Q  ++L E         L+  F    + A      +  FVGR+   
Sbjct: 749 DKIVVRLXSELETYQKEEKLSEDQAFEIGKYLILQFRGLFSNAHRFAKAVEDFVGRLHGG 928

Query: 197 HVANTDKKSYEPQE 210
                D+ +  PQE
Sbjct: 929 QNGGADENNGGPQE 970
>38660
          Length = 744

 Score = 31.2 bits (69), Expect = 0.64,   Method: Compositional matrix adjust.
 Identities = 22/83 (26%), Positives = 38/83 (45%), Gaps = 1/83 (1%)
 Frame = +2

Query: 52  AAQMPAYQELVEEAIAYGKKLGGPQEEQIKNAIDKLFVLFGAEILKKIPGRVS-TEVDAR 110
           + Q   Y+ LV   + Y   +  PQ++ ++ ++DK+       IL       S TE+ +R
Sbjct: 425 STQTTCYKGLVRPVLEYVSSVWDPQQQYLQTSLDKVQRRSARRILHDFSLTSSATELVSR 604

Query: 111 LSFDKDAMVARARRLIELYKEAG 133
           L+ D  +    A R   +YK  G
Sbjct: 605 LNLDPLSFRRTAARATMMYKIMG 673
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|41235738|ref|NP_958745.1| tumor suppressing
subtransferable candidate 1 [Mus musculus]
         (386 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

15745                                                                 253   e-102
21476                                                                 119   1e-27
03387                                                                  67   2e-11
01768                                                                  53   2e-07
04395                                                                  40   0.001
12806                                                                  39   0.004
16105                                                                  38   0.006
19498                                                                  38   0.008
26939                                                                  38   0.009
01805                                                                  37   0.009
07781                                                                  37   0.013
20662                                                                  37   0.019
17602                                                                  35   0.041
10264                                                                  35   0.049
02960                                                                  35   0.068
30256                                                                  34   0.080
27475                                                                  34   0.082
12140                                                                  34   0.083
27465                                                                  34   0.091
00561                                                                  34   0.12 
19949                                                                  33   0.22 
09883                                                                  33   0.23 
31474                                                                  32   0.48 
01598                                                                  32   0.55 
16199                                                                  31   0.66 
33180                                                                  31   0.85 
17598                                                                  31   0.92 
12960                                                                  31   1.1  
04358                                                                  30   2.0  
12574                                                                  30   2.0  
00825                                                                  30   2.1  
37142                                                                  30   2.1  
19863                                                                  29   3.1  
21763                                                                  28   4.9  
20271                                                                  28   6.0  
13890                                                                  28   9.2  
>15745
          Length = 1183

 Score =  253 bits (645), Expect(3) = e-102,   Method: Compositional matrix adjust.
 Identities = 118/216 (54%), Positives = 158/216 (73%)
 Frame = +2

Query: 63  QAGEIWHISASPADKGVLATCYNKTTDSRVQACAAVWRMPKELESGSHESPDDPASTAQT 122
           Q GE+WHISA+  D  +LATCYNKT++S+ +  AAVWR+P +++  S    DD +S+  +
Sbjct: 224 QGGEVWHISAATFDSSLLATCYNKTSESKSELRAAVWRLPGDVDPSS--PADDQSSSHSS 397

Query: 123 LELLCHLDNSAQGNVACVVWEPMGDGKKVISLADSHILLWDLQPSSSQAVLASSATLEGR 182
           L  LCHL +S+  +V  ++W P GD + V+ + +  +++WDL  +SS A      TLEG+
Sbjct: 398 LLPLCHL-HSSDHDVKGILWHPTGDSQTVLGVCEDRVIMWDLNVASSSAQQTDMITLEGK 574

Query: 183 GQLKFTAGRWSPHHNCTQVATASDTTLRGWDTRSMSQIYCIENAHGQLVRDLDFNPNKQY 242
           GQ + T GRW+PHHNC Q+ATA++ T+RGWD RS  Q Y +E AHGQLVRDLDFNPN+QY
Sbjct: 575 GQPRLTCGRWNPHHNCAQIATANEATIRGWDLRSKQQTYQMEGAHGQLVRDLDFNPNRQY 754

Query: 243 YLASCGDDCKVKFWDTRNVTEPVKTLEEHSHWVWSV 278
           YLASCGDDC+VKFWDTRN +EP+K L +HSHWVW  
Sbjct: 755 YLASCGDDCRVKFWDTRNCSEPLKVLSDHSHWVWGC 862

 Score =  109 bits (273), Expect(3) = e-102,   Method: Compositional matrix adjust.
 Identities = 61/89 (68%), Positives = 74/89 (83%)
 Frame = +1

Query: 278 VRYNHSHDQLVLTGSSDSRVILSNMVSISSEPFGHLVDDDDVSDPEEHHAEKSKEPLQDN 337
           VRYNH HDQLVLT SSDSRVIL+N+V++SSEP+GHL+D DD SD +  H E+ +EP  D 
Sbjct: 859 VRYNHFHDQLVLTSSSDSRVILNNVVTLSSEPYGHLLDKDDDSDSDSLH-ERPQEPPTDG 1035

Query: 338 VIATYEEHEDSVYAVDWASADPWLFASLS 366
           VIATYEEHEDSVYAV W++ADPW+F  L+
Sbjct: 1036VIATYEEHEDSVYAVAWSTADPWVFLRLA 1122

 Score = 48.1 bits (113), Expect(3) = e-102,   Method: Compositional matrix adjust.
 Identities = 23/28 (82%), Positives = 24/28 (85%)
 Frame = +3

Query: 359  PWLFASLSYDGRLVINRVPRALKYHILL 386
            P  F+SLSYDGRLVINRVPRA KY ILL
Sbjct: 1098 PLGFSSLSYDGRLVINRVPRAEKYKILL 1181

 Score = 83.6 bits (205), Expect = 1e-16,   Method: Compositional matrix adjust.
 Identities = 48/107 (44%), Positives = 58/107 (54%), Gaps = 8/107 (7%)
 Frame = +3

Query: 1   MEDDAPVIYGLEFQARALTPQTAETDAIRFLVGTQSLKYDNQXXXXXXXXXXXXXXKNVL 60
           MED+APVIYGLEFQAR+LT QTAETD IRFLVGTQSL+ +NQ              KNV 
Sbjct: 39  MEDEAPVIYGLEFQARSLTAQTAETDRIRFLVGTQSLRSENQVHHIDFDDENNVINKNVF 218

Query: 61  LHQAGEIWH--------ISASPADKGVLATCYNKTTDSRVQACAAVW 99
           LH+ G            +S+ PA         N++ + R   C   W
Sbjct: 219 LHREGRYGTSVLPPSTALSSQPATTKRQRA--NQSCERRCGGCRVTW 353
>21476
          Length = 431

 Score =  119 bits (299), Expect = 1e-27,   Method: Compositional matrix adjust.
 Identities = 55/117 (47%), Positives = 82/117 (70%)
 Frame = +3

Query: 270 EHSHWVWSVRYNHSHDQLVLTGSSDSRVILSNMVSISSEPFGHLVDDDDVSDPEEHHAEK 329
           +HSHWVWSVR+N  HDQL+L+ SSD +V+L+   S+SSE  G    +   +  +E H   
Sbjct: 9   DHSHWVWSVRFNTFHDQLILSSSSDCKVLLTCAGSVSSETQGTETGEVGAAVNQERH--- 179

Query: 330 SKEPLQDNVIATYEEHEDSVYAVDWASADPWLFASLSYDGRLVINRVPRALKYHILL 386
             + L D ++ T+++HEDSVY  +W++ DPW+FASLSYDGR++I++VP+  KY I+ 
Sbjct: 180 --KVLSDGLLQTFDQHEDSVYCAEWSNVDPWIFASLSYDGRVLISKVPKQYKYQIIF 344
>03387
          Length = 1891

 Score = 66.6 bits (161), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 53/234 (22%), Positives = 99/234 (42%), Gaps = 2/234 (0%)
 Frame = +1

Query: 142 WEPMGDGKKVISLADSHILLWDLQPSSSQAVLASSATLEGRGQLKFTAGRWSPHHNCTQV 201
           W P  +G  + +  D  I LWD+  +  ++ +  + T+            W   H     
Sbjct: 385 WNPNLNGHLLSASDDHTICLWDINSTQRESRVVDAHTIFTGHTSVVEDVAWHLLHESLFG 564

Query: 202 ATASDTTLRGWDTRS--MSQIYCIENAHGQLVRDLDFNPNKQYYLASCGDDCKVKFWDTR 259
           + A D  L  WDTRS   S+   + +AH   V  L FNP  ++ LA+   D  V  WD R
Sbjct: 565 SVADDQKLMIWDTRSNTTSKPSHVVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLR 744

Query: 260 NVTEPVKTLEEHSHWVWSVRYNHSHDQLVLTGSSDSRVILSNMVSISSEPFGHLVDDDDV 319
           N+   + + E H   ++ V+++  ++ ++ +  +D R+ + ++  I  E    L +D + 
Sbjct: 745 NLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLHVWDLSKIGEE---QLPEDAED 915

Query: 320 SDPEEHHAEKSKEPLQDNVIATYEEHEDSVYAVDWASADPWLFASLSYDGRLVI 373
             PE              ++  +  H   +    W   +PW+  S+S D  + +
Sbjct: 916 GPPE--------------LLFIHGGHTAKISDFSWNPNEPWIVCSVSEDNIMQV 1035

 Score = 37.0 bits (84), Expect = 0.015,   Method: Compositional matrix adjust.
 Identities = 37/168 (22%), Positives = 69/168 (41%), Gaps = 30/168 (17%)
 Frame = +1

Query: 234 LDFNPNKQYYLASCGDDCKVKFWDTRNVTEPVKTLEEHSHW------VWSVRYNHSHDQL 287
           L +NPN   +L S  DD  +  WD  +     + ++ H+ +      V  V ++  H+ L
Sbjct: 379 LSWNPNLNGHLLSASDDHTICLWDINSTQRESRVVDAHTIFTGHTSVVEDVAWHLLHESL 558

Query: 288 VLTGSSDSRVILSNMVSISSEPFGHLVDDDDVSDPEEHHAEK---SKEPLQDNVIAT--- 341
             + + D ++++ +  S ++    H+VD         H AE    S  P  + ++AT   
Sbjct: 559 FGSVADDQKLMIWDTRSNTTSKPSHVVD--------AHTAEVNCLSFNPYSEFILATGSA 714

Query: 342 ------------------YEEHEDSVYAVDWASADPWLFASLSYDGRL 371
                             +E H+D ++ V W+  +  + AS   D RL
Sbjct: 715 DKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRL 858
>01768
          Length = 1424

 Score = 53.1 bits (126), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 32/116 (27%), Positives = 60/116 (51%), Gaps = 7/116 (6%)
 Frame = +3

Query: 191 RWSPHHNCTQVATASDTTLRGWDTR---SMSQIYCIENAHGQLVRDLDFNPNKQYYLASC 247
           +WSP+      + + D TLR W+T+   S + +  +  AH + +  +++NP +++ LAS 
Sbjct: 858 QWSPNEGNVFASCSVDRTLRIWNTQQKPSKANVLTVPEAHSRDINVINWNPIEKHLLASG 1037

Query: 248 GDDCKVKFWDTRNV-TEPVK---TLEEHSHWVWSVRYNHSHDQLVLTGSSDSRVIL 299
           GDD  +K WD R    +PV    + + HS  V S+ +N     ++     D ++ +
Sbjct: 1038GDDGIIKIWDLRMFRNKPVSAQASFKLHSQPVTSLEWNPQDSSVLAASGEDDQITI 1205

 Score = 36.2 bits (82), Expect = 0.021,   Method: Compositional matrix adjust.
 Identities = 29/126 (23%), Positives = 46/126 (36%), Gaps = 4/126 (3%)
 Frame = +3

Query: 136 NVACVVWEPMGDGKKVISLADSHILLWDLQPSSSQAVLASSATLEGRGQLKFTAGRWSPH 195
           +V  V W P           D  + +W+ Q   S+A + +      R         W+P 
Sbjct: 843 SVEDVQWSPNEGNVFASCSVDRTLRIWNTQQKPSKANVLTVPEAHSR---DINVINWNPI 1013

Query: 196 HNCTQVATASDTTLRGWDTRSMSQIYCIENA----HGQLVRDLDFNPNKQYYLASCGDDC 251
                 +   D  ++ WD R          A    H Q V  L++NP     LA+ G+D 
Sbjct: 1014EKHLLASGGDDGIIKIWDLRMFRNKPVSAQASFKLHSQPVTSLEWNPQDSSVLAASGEDD 1193

Query: 252 KVKFWD 257
           ++  WD
Sbjct: 1194QITIWD 1211
>04395
          Length = 1145

 Score = 40.4 bits (93), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 26/93 (27%), Positives = 46/93 (49%), Gaps = 4/93 (4%)
 Frame = +3

Query: 209 LRGWDTRSMS----QIYCIENAHGQLVRDLDFNPNKQYYLASCGDDCKVKFWDTRNVTEP 264
           L+ +D R  S    QI+   + H  L+  +D +P + + +A+   D  +  WD R+   P
Sbjct: 408 LKLFDVRQNSDEPAQIFSATDDHWSLLC-VDKHPGQLHIVATGSQDGTLTVWDLRHHRFP 584

Query: 265 VKTLEEHSHWVWSVRYNHSHDQLVLTGSSDSRV 297
           + TL+ H   +W VR++  H   + T S D  +
Sbjct: 585 MTTLDAHHSSMWEVRFHQQHTPHLFTCSEDGSL 683
>12806
          Length = 961

 Score = 38.9 bits (89), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 38/148 (25%), Positives = 65/148 (43%), Gaps = 5/148 (3%)
 Frame = +3

Query: 156 DSHILLWDLQPSSS----QAVLASSATLEGRGQLKFTAGRWSPHHNCTQVATASDTTLRG 211
           D++I++WDL P       Q       TL G     F +       +   ++++ D TLR 
Sbjct: 72  DNNIIVWDL*PKKDGDEDQTWGVPRKTLTGHSH--FISDLALSADSRFALSSSWDATLRL 245

Query: 212 WDTRSMSQIYCIENAHGQLVRDLDFNP-NKQYYLASCGDDCKVKFWDTRNVTEPVKTLEE 270
           WD +  S      N H + V  + F+P N+Q  +AS G D  +K W+     +       
Sbjct: 246 WDIKKGSTTSRFIN-HTRDVLTVAFSPDNRQ--IASGGRDKNLKIWNIMGECKYTVDANA 416

Query: 271 HSHWVWSVRYNHSHDQLVLTGSSDSRVI 298
           H+ WV  VR++      ++  +S+ + I
Sbjct: 417 HTDWVTCVRFHQDTKNPIVVSASNDKTI 500
>16105
          Length = 960

 Score = 38.1 bits (87), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 21/83 (25%), Positives = 40/83 (48%), Gaps = 6/83 (7%)
 Frame = -2

Query: 226 AHGQLVRDLDFNPNKQYYLASCGDDCKVKFWD------TRNVTEPVKTLEEHSHWVWSVR 279
            H   V D+ + P+    +AS  DDC VK W         N+T+PV  L  H      + 
Sbjct: 581 GHKGAVLDIQWCPHNDNVIASASDDCTVKVWQIPDSGLVTNLTDPVVDLVGHQKRCCLIV 402

Query: 280 YNHSHDQLVLTGSSDSRVILSNM 302
           ++ S   ++++  +D++++  N+
Sbjct: 401 WHPSAQNVLVSAGADNKILFWNV 333
>19498
          Length = 903

 Score = 37.7 bits (86), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 40/151 (26%), Positives = 66/151 (43%), Gaps = 11/151 (7%)
 Frame = -1

Query: 124 ELLCHLDNSAQGNVACVVWEPMGDGKKVISLADSH-ILLWDLQPS-SSQAVLASSATL-- 179
            +LC +D S  G V CV W    +GK + S  D   I++W +     S     S+ T+  
Sbjct: 813 RVLCQMD-SHLGCVNCVRWSE--NGKFLASGGDDKLIMIWQISRGFGSGKSFGSNVTILE 643

Query: 180 --EGRGQLKFTAG-----RWSPHHNCTQVATASDTTLRGWDTRSMSQIYCIENAHGQLVR 232
                  L+  AG      WSP  +    + + D T+  W+    S+   +   H  +V+
Sbjct: 642 HWRSVATLRGHAGDVLDLAWSPQ-DLWLASCSVDNTIVVWNALKFSEQVAVIRGHAGMVK 466

Query: 233 DLDFNPNKQYYLASCGDDCKVKFWDTRNVTE 263
            + ++P  +Y LAS  DD  ++ W T +  E
Sbjct: 465 GVTWDPVGRY-LASQSDDKTLRVWRTSDWKE 376
>26939
          Length = 388

 Score = 37.7 bits (86), Expect = 0.009,   Method: Compositional matrix adjust.
 Identities = 21/55 (38%), Positives = 31/55 (56%)
 Frame = +2

Query: 243 YLASCGDDCKVKFWDTRNVTEPVKTLEEHSHWVWSVRYNHSHDQLVLTGSSDSRV 297
           YL S  DD  ++ WD RN    +KTL  H H+  S+ ++ +H   V++GS D  V
Sbjct: 8   YLVSASDDKTIRVWDLRN-KRCMKTLYAHQHFCTSIDFHKAH-PYVISGSVDQTV 166
>01805
          Length = 2124

 Score = 37.4 bits (85), Expect = 0.009,   Method: Compositional matrix adjust.
 Identities = 24/72 (33%), Positives = 34/72 (47%)
 Frame = -1

Query: 226 AHGQLVRDLDFNPNKQYYLASCGDDCKVKFWDTRNVTEPVKTLEEHSHWVWSVRYNHSHD 285
            H Q V DL +N N ++ LAS   D  V  WD     +      +HS  V    ++   +
Sbjct: 582 GHTQAVLDLSWNRNARHVLASASADTTVALWDLSE-GKMAMNFTQHSREVQCCNWHPQEE 406

Query: 286 QLVLTGSSDSRV 297
           Q +LTGS D+ V
Sbjct: 405 QTLLTGSFDNTV 370
>07781
          Length = 1269

 Score = 37.0 bits (84), Expect = 0.013,   Method: Compositional matrix adjust.
 Identities = 35/130 (26%), Positives = 51/130 (39%), Gaps = 18/130 (13%)
 Frame = -2

Query: 244 LASCGDDCKVKFWDTRNVTEPVKTLEEHSHWVWSVRYNHSHDQLVLTGSSDSRVILSNMV 303
           + S  DDCK+K WD R  T PV T    +  V S++     + L+  GS D  + L +  
Sbjct: 746 IYSGSDDCKLKVWDLRVGTTPVLTNSRFTMGVTSIQSCPQREHLLAVGSYDENLRLFDTR 567

Query: 304 SISSEPFGHLVDDDDV----SDP------------EEHHAEKSKEPLQD--NVIATYEEH 345
            +  +P      +  V     DP               H   S +P +D   V++ Y  H
Sbjct: 566 HM-RQPLSTTALEGGVWRVKWDPFXARYVLTATMHNGFHIVDSSKPEEDCLRVVSHYTNH 390

Query: 346 EDSVYAVDWA 355
               Y VDW 
Sbjct: 389 TSLAYGVDWC 360
>20662
          Length = 1220

 Score = 36.6 bits (83), Expect = 0.019,   Method: Compositional matrix adjust.
 Identities = 25/97 (25%), Positives = 40/97 (41%)
 Frame = +2

Query: 156 DSHILLWDLQPSSSQAVLASSATLEGRGQLKFTAGRWSPHHNCTQVATASDTTLRGWDTR 215
           D  I+LWD++ S     L   ++       K T  +W P+             +   D R
Sbjct: 575 DGKIVLWDVRESKPATCLPKCSS-----GFKPTCVQWQPNARNMYAVGDEGGHVSVQDLR 739

Query: 216 SMSQIYCIENAHGQLVRDLDFNPNKQYYLASCGDDCK 252
            + +      +H ++V  L F P +   LAS G+DCK
Sbjct: 740 MVVEKNVSYQSHNRVVTRLAFCPQRPSMLASIGEDCK 850

 Score = 35.4 bits (80), Expect = 0.041,   Method: Compositional matrix adjust.
 Identities = 29/124 (23%), Positives = 53/124 (42%)
 Frame = +2

Query: 149 KKVISLADSHILLWDLQPSSSQAVLASSATLEGRGQLKFTAGRWSPHHNCTQVATASDTT 208
           K ++ L    + LW+LQ       + SSA          +      H+    ++ + D  
Sbjct: 290 KVLVGLDTGGVALWELQDEDKMFSMLSSACEHDDMTASVSINSDXSHY----LSASYDHG 457

Query: 209 LRGWDTRSMSQIYCIENAHGQLVRDLDFNPNKQYYLASCGDDCKVKFWDTRNVTEPVKTL 268
           ++ W+T  ++ +Y    AH  +V D+  +P +     SC  D K+  WD R  ++P   L
Sbjct: 458 IKVWNT-DLTSLYTYR-AHSDIVWDVQCHPTEPALFLSCSQDGKIVLWDVRE-SKPATCL 628

Query: 269 EEHS 272
            + S
Sbjct: 629 PKCS 640

 Score = 30.0 bits (66), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 14/35 (40%), Positives = 20/35 (57%)
 Frame = +2

Query: 339 IATYEEHEDSVYAVDWASADPWLFASLSYDGRLVI 373
           + TY  H D V+ V     +P LF S S DG++V+
Sbjct: 488 LYTYRAHSDIVWDVQCHPTEPALFLSCSQDGKIVL 592
>17602
          Length = 481

 Score = 35.4 bits (80), Expect = 0.041,   Method: Compositional matrix adjust.
 Identities = 28/105 (26%), Positives = 53/105 (50%), Gaps = 2/105 (1%)
 Frame = +3

Query: 201 VATASDTTLRGWDTRSMSQIYCIENAHGQLVRDLDFNPNKQYYLASCGDDCKVKFWDTRN 260
           V+++ D   R WDT S   +  + +     V  + F+PN +Y LA+  D+  +K WD   
Sbjct: 102 VSSSYDGLCRIWDTASGQCLXTLIDDDNPPVSFVKFSPNGKYILAATLDN-TLKLWDYSK 278

Query: 261 VTEPVKTLEEHSHWVWSVRYNHS--HDQLVLTGSSDSRVILSNMV 303
             + +KT   H +  + +  N S    + +++GS D+ V + N++
Sbjct: 279 -GKCLKTYVGHRNEKYCIFANFSVTGGKWIVSGSEDNMVYIWNLL 410
>10264
          Length = 416

 Score = 35.0 bits (79), Expect = 0.049,   Method: Compositional matrix adjust.
 Identities = 20/73 (27%), Positives = 36/73 (49%)
 Frame = -1

Query: 225 NAHGQLVRDLDFNPNKQYYLASCGDDCKVKFWDTRNVTEPVKTLEEHSHWVWSVRYNHSH 284
           + H Q V D+ ++P+    L S G D +   WD +  T  +   + H   + + +++   
Sbjct: 254 SGHSQRVTDMSWSPHHDARLVSVGYDAEAFVWDVQKGT-ALAQFKGHMGRLLTCQFSGLD 78

Query: 285 DQLVLTGSSDSRV 297
             LV+TG SD+ V
Sbjct: 77  PDLVMTGGSDASV 39

 Score = 32.3 bits (72), Expect = 0.35,   Method: Compositional matrix adjust.
 Identities = 23/93 (24%), Positives = 36/93 (38%)
 Frame = -1

Query: 172 VLASSATLEGRGQLKFTAGRWSPHHNCTQVATASDTTLRGWDTRSMSQIYCIENAHGQLV 231
           +L S   L G  Q + T   WSPHH+   V+   D     WD +  + +   +   G+L+
Sbjct: 278 ILTSLRELSGHSQ-RVTDMSWSPHHDARLVSVGYDAEAFVWDVQKGTALAQFKGHMGRLL 102

Query: 232 RDLDFNPNKQYYLASCGDDCKVKFWDTRNVTEP 264
               F+      + + G D  V  W       P
Sbjct: 101 -TCQFSGLDPDLVMTGGSDASVHVWRVSQQAAP 6
>02960
          Length = 1577

 Score = 34.7 bits (78), Expect = 0.068,   Method: Compositional matrix adjust.
 Identities = 23/92 (25%), Positives = 46/92 (50%)
 Frame = +2

Query: 220  IYCIENAHGQLVRDLDFNPNKQYYLASCGDDCKVKFWDTRNVTEPVKTLEEHSHWVWSVR 279
            + C   +H   V  +D++P +++   S   D  +K WDTR+    +  +  H   + +V 
Sbjct: 1190 VKCAFTSHTGWVTGVDWSPTREHLFLSGSYDNVLKLWDTRSPKATLYDMNWHEDRILAVD 1369

Query: 280  YNHSHDQLVLTGSSDSRVILSNMVSISSEPFG 311
            +  S  +L+L+G  D+++   ++ S SS   G
Sbjct: 1370 W--SIPELLLSGGVDNKL---HVFSYSSAKLG 1450

 Score = 28.5 bits (62), Expect = 4.3,   Method: Compositional matrix adjust.
 Identities = 34/138 (24%), Positives = 55/138 (39%), Gaps = 19/138 (13%)
 Frame = +2

Query: 264  PVKTLEEHSHWVWSVRYNHSHDQLVLTGSSDSRVILSNM---------------VSISSE 308
            PV TL  H+  V +VR+   H   V+T S D  + L ++               + ++  
Sbjct: 935  PVLTLSGHAEAVSAVRWLDPHR--VVTSSWDHSLRLWDLHTAQQTSLIQGSKAVLDVAYS 1108

Query: 309  PFGHLVDDDDVSDPEEHHAE--KSKEPLQDNVIATYEEHEDSVYAVDWASADPWLFASLS 366
            P  H++    ++   + H      +    + V   +  H   V  VDW+     LF S S
Sbjct: 1109 PLSHML----ITGSADRHVRLVDPRCSEGETVKCAFTSHTGWVTGVDWSPTREHLFLSGS 1276

Query: 367  YDGRLVI--NRVPRALKY 382
            YD  L +   R P+A  Y
Sbjct: 1277 YDNVLKLWDTRSPKATLY 1330
>30256
          Length = 961

 Score = 34.3 bits (77), Expect = 0.080,   Method: Compositional matrix adjust.
 Identities = 40/150 (26%), Positives = 64/150 (42%), Gaps = 7/150 (4%)
 Frame = +3

Query: 141 VWEPMGDGKKVISLA-DSHILLWDLQPSSSQAVLASSATLEGRGQLKFTAGRWSPHHNCT 199
           V+    DG  V+S + D+ I +WD++       L    +L    +LK          +  
Sbjct: 411 VYSLQFDGVYVVSGSLDTSIRVWDVRCGKLVHTLMGHQSLTSGLELK----------DNL 560

Query: 200 QVATASDTTLRGWD--TRSMSQIYCIENAHGQLVRDLDFNPNKQYYLASCGDDCKVKFWD 257
            V+  +D+T++ WD  T    Q     N H   V  L FN   + ++ +C DD  VK WD
Sbjct: 561 LVSGNADSTVKVWDVHTGKCLQTLLGPNKHRSAVTCLQFN---KKFVVTCSDDGTVKLWD 731

Query: 258 --TRNVTEPVKTLEEHSHW--VWSVRYNHS 283
             T +    + TL        VW +R N++
Sbjct: 732 LNTGDFIRNLITLPSGGSGGVVWRLRCNNT 821
>27475
          Length = 369

 Score = 34.3 bits (77), Expect = 0.082,   Method: Compositional matrix adjust.
 Identities = 23/92 (25%), Positives = 46/92 (50%)
 Frame = +2

Query: 220 IYCIENAHGQLVRDLDFNPNKQYYLASCGDDCKVKFWDTRNVTEPVKTLEEHSHWVWSVR 279
           + C   +H   V  +D++P +++   S   D  +K WDTR+    +  +  H   + +V 
Sbjct: 44  VKCAFTSHTGWVTGVDWSPTREHLFLSGSYDNVLKLWDTRSPKATLYDMNWHEDRILAVD 223

Query: 280 YNHSHDQLVLTGSSDSRVILSNMVSISSEPFG 311
           +  S  +L+L+G  D+++   ++ S SS   G
Sbjct: 224 W--SIPELLLSGGVDNKL---HVFSYSSAKLG 304

 Score = 27.7 bits (60), Expect = 9.2,   Method: Compositional matrix adjust.
 Identities = 17/51 (33%), Positives = 23/51 (45%), Gaps = 2/51 (3%)
 Frame = +2

Query: 336 DNVIATYEEHEDSVYAVDWASADPWLFASLSYDGRLVI--NRVPRALKYHI 384
           + V   +  H   V  VDW+     LF S SYD  L +   R P+A  Y +
Sbjct: 38  ETVKCAFTSHTGWVTGVDWSPTREHLFLSGSYDNVLKLWDTRSPKATLYDM 190
>12140
          Length = 727

 Score = 34.3 bits (77), Expect = 0.083,   Method: Compositional matrix adjust.
 Identities = 33/126 (26%), Positives = 56/126 (44%), Gaps = 16/126 (12%)
 Frame = +2

Query: 226 AHGQLVRDLDFNPN---KQYYLASCGDDCKVKFW--DTRNVTEPVKTLEEHSHWVWSVRY 280
            H   VRD+ + P+    +  +ASC  DC+V  W  D  +     + L + S  VW V +
Sbjct: 350 GHSDWVRDVAWAPSIGLPRNVIASCSQDCRVIIWTNDGSSNQWTSRILNKFSDVVWHVSW 529

Query: 281 NHSHDQLVLTGSSDSRVILSN--------MVSISSEPFGHLVDDDDVSDP---EEHHAEK 329
           + + + L ++G  D++V L           +S  ++  GH+ D    S+P        E 
Sbjct: 530 SVTGNILAVSG-GDNKVTLWKESVEGQWTCISDVNKGQGHITDQRSSSEPSYNSRRRIEL 706

Query: 330 SKEPLQ 335
            K+P Q
Sbjct: 707 *KKPSQ 724
>27465
          Length = 658

 Score = 34.3 bits (77), Expect = 0.091,   Method: Compositional matrix adjust.
 Identities = 23/81 (28%), Positives = 42/81 (51%), Gaps = 1/81 (1%)
 Frame = -1

Query: 220 IYCIENAHGQLVRDLDFNPNKQYYLASCGD-DCKVKFWDTRNVTEPVKTLEEHSHWVWSV 278
           ++ +  AH   + ++ FN +   ++    D  CK+  WDT +  E + TLE H + V+++
Sbjct: 385 LFKVLRAHILPLTNVAFNKSGSSFITGSYDRTCKI--WDTASA-EELHTLEGHRNVVYAI 215

Query: 279 RYNHSHDQLVLTGSSDSRVIL 299
            +N+     V+TGS D    L
Sbjct: 214 AFNNPFGDKVITGSFDKTCKL 152
>00561
          Length = 1003

 Score = 33.9 bits (76), Expect = 0.12,   Method: Compositional matrix adjust.
 Identities = 32/117 (27%), Positives = 47/117 (40%), Gaps = 2/117 (1%)
 Frame = -3

Query: 147 DGKKVISLA-DSHILLWDLQPSSSQAVLASSATLEGRGQLKFTAGRWSPHHNCTQVATAS 205
           DG   +S + D  + LWDL         A   T    G  K          N   V+ + 
Sbjct: 833 DGNYALSGSWDQTLRLWDLA--------AGKTTRRFEGHTKDVLSVAFSADNRQIVSGSR 678

Query: 206 DTTLRGWDTRSMSQIYCIENAHGQLVRDLDFNPN-KQYYLASCGDDCKVKFWDTRNV 261
           D T++ W+T +  +    E+ H   V  + F+PN     + SCG D  VK W+  N 
Sbjct: 677 DKTIKLWNTLAECKFTIQEDGHTDWVSCVRFSPNHSNPIIVSCGWDRTVKVWNLANC 507
>19949
          Length = 903

 Score = 33.1 bits (74), Expect = 0.22,   Method: Compositional matrix adjust.
 Identities = 37/140 (26%), Positives = 67/140 (47%), Gaps = 9/140 (6%)
 Frame = +2

Query: 185 LKFTA-GRWSPHHNCTQVATAS-DTTLRGWDTRSMSQIYCIENAHGQLVRDLDFNPNKQY 242
           L+F+  GRW        +A+AS D  ++ WD  +  ++      H   V  ++F+P+ ++
Sbjct: 137 LRFSPDGRW--------IASASEDGLVKLWDL-TAGKLLTDLKLHRDAVNTIEFHPH-EF 286

Query: 243 YLASCGDDCKVKFWDTRNVTEPVKTLEEHSHWVWSVRYNHSHDQLVLTGSSDSRVI---- 298
            LAS   D  VKFWD     + + T E  ++ + S+ + H     + +GS D+  +    
Sbjct: 287 LLASGSADRTVKFWDLETF-QLISTTEPEANSIRSILF-HPDGVCLYSGSKDTLKVYHWE 460

Query: 299 ---LSNMVSISSEPFGHLVD 315
              L + VS+   P+G + D
Sbjct: 461 PLELYDTVSV---PWGQVCD 511

 Score = 31.6 bits (70), Expect = 0.58,   Method: Compositional matrix adjust.
 Identities = 19/51 (37%), Positives = 27/51 (52%)
 Frame = +2

Query: 231 VRDLDFNPNKQYYLASCGDDCKVKFWDTRNVTEPVKTLEEHSHWVWSVRYN 281
           V+ LDF+P   Y  AS   DC VK WD R     + T + H+  V  +R++
Sbjct: 2   VKSLDFHPYGAY-TASGSMDCNVKLWDIRR-KGCIYTYKGHTGCVCCLRFS 148
>09883
          Length = 650

 Score = 32.7 bits (73), Expect = 0.23,   Method: Compositional matrix adjust.
 Identities = 20/82 (24%), Positives = 40/82 (48%), Gaps = 1/82 (1%)
 Frame = +3

Query: 169 SQAVLASSATLEGRGQLKFTA-GRWSPHHNCTQVATASDTTLRGWDTRSMSQIYCIENAH 227
           ++ + +   TLEG   +  +  GR         VA  S +++  WD  +  +++ + + H
Sbjct: 9   AKLLFSGPVTLEGASLIALSPDGR--------TVAICSQSSVVFWDAVACEEMHTLHSLH 164

Query: 228 GQLVRDLDFNPNKQYYLASCGD 249
            + +  L F+ N  +YL +CGD
Sbjct: 165 AEPITALAFD-NSNHYLVTCGD 227
>31474
          Length = 403

 Score = 32.0 bits (71), Expect = 0.48,   Method: Compositional matrix adjust.
 Identities = 34/140 (24%), Positives = 55/140 (39%)
 Frame = -3

Query: 216 SMSQIYCIENAHGQLVRDLDFNPNKQYYLASCGDDCKVKFWDTRNVTEPVKTLEEHSHWV 275
           ++ ++ C+ +AH +    + +NP     LASCG D  +K W            +E  +WV
Sbjct: 338 TLEEVCCL-SAHDEHAWCVAWNPTGTL-LASCGSDKIIKIWG-----------KEGDNWV 198

Query: 276 WSVRYNHSHDQLVLTGSSDSRVILSNMVSISSEPFGHLVDDDDVSDPEEHHAEKSKEPLQ 335
                  +H + V               S+   P G+ +            A  S++  +
Sbjct: 197 CKSTLTDAHTRTVR--------------SLGWSPCGNYLSSASFDATT---AVWSRKGGE 69

Query: 336 DNVIATYEEHEDSVYAVDWA 355
              IAT E HE+ V AV WA
Sbjct: 68  FECIATLEGHENEVKAVAWA 9
>01598
          Length = 1545

 Score = 31.6 bits (70), Expect = 0.55,   Method: Compositional matrix adjust.
 Identities = 23/93 (24%), Positives = 36/93 (38%)
 Frame = +1

Query: 172  VLASSATLEGRGQLKFTAGRWSPHHNCTQVATASDTTLRGWDTRSMSQIYCIENAHGQLV 231
            +L S   L G  Q + T   WSPHH+   V+   D     WD +  + +   +   G+L+
Sbjct: 1267 ILTSLRELSGHSQ-RVTDMSWSPHHDARLVSVGYDAEAFVWDVQKGTALAQFKGHMGRLL 1443

Query: 232  RDLDFNPNKQYYLASCGDDCKVKFWDTRNVTEP 264
                F+      + + G D  V  W       P
Sbjct: 1444 T-CQFSGLDPDLVMTGGSDASVHVWRVSQQAAP 1539
>16199
          Length = 694

 Score = 31.2 bits (69), Expect = 0.66,   Method: Compositional matrix adjust.
 Identities = 22/59 (37%), Positives = 33/59 (55%), Gaps = 1/59 (1%)
 Frame = +1

Query: 242 YYLASCGDDCKVKFWDTRNVTEPVKTLEEHSHW-VWSVRYNHSHDQLVLTGSSDSRVIL 299
           YYLA+  +D  VK WD R + +  KTL+    + V ++ ++ S   L + G SD RV L
Sbjct: 235 YYLATSAEDSVVKLWDLRKL-KNFKTLQLGDKYEVKALCFDQSGTYLAVAG-SDVRVYL 405
>33180
          Length = 460

 Score = 30.8 bits (68), Expect = 0.85,   Method: Compositional matrix adjust.
 Identities = 27/83 (32%), Positives = 35/83 (42%), Gaps = 4/83 (4%)
 Frame = -2

Query: 197 NCTQVATASDTTLRGWDTRSMSQIYCIENAHGQLVRDLDFNPNKQYYLASCGDDCKVKFW 256
           N   V  A+D  L  +D  S  +   I+ AH   V  + F  +    L S GDD   K W
Sbjct: 417 NTEIVGGANDGCLYVYDRESNQRTLKID-AHDDDVNAVAFADDSSQILYSGGDDGLCKVW 241

Query: 257 DTRNVTE----PVKTLEEHSHWV 275
           D R + E    PV  +  HS  V
Sbjct: 240 DRRTLREDNPLPVGIMAGHSDGV 172
>17598
          Length = 875

 Score = 30.8 bits (68), Expect = 0.92,   Method: Compositional matrix adjust.
 Identities = 44/180 (24%), Positives = 85/180 (47%), Gaps = 14/180 (7%)
 Frame = +1

Query: 201 VATASDTTLRGWDTRSMSQIYCIENAHGQLVRDLDFNP-NKQYYLASCGDDCKVKFWDTR 259
           ++++ D TLR WD +  +       +H +    + F+P N+Q  +AS G D  +K W+T 
Sbjct: 169 LSSSWDATLRLWDIKKGNTTRRFI-SHTRDALAVAFSPDNRQ--IASGGRDKALKIWNT- 336

Query: 260 NVTEPVKTLEEHSH--WVWSVRYNH-SHDQLVLTGSSDSRVIL--SNMVSISSEPFGHL- 313
            V E   T++ +SH  WV  V+++  +   LV++ S D  + +  +  +++     GH  
Sbjct: 337 -VGECKFTVDANSHQDWVTCVKFHQDAKSPLVVSASMDKTIKVWDNQTMTLKHTFVGHKT 513

Query: 314 -VDDDDVSDPEEHHAEKSKEP------LQDNVIATYEEHEDSVYAVDWASADPWLFASLS 366
            ++  D++    + A  SK+       +Q+       + +  V AV ++    WLF   S
Sbjct: 514 QINAIDLALKTYYLASGSKDGIVMTWNIQNGTFLGKIDCDCEVNAVKFSPNKYWLFVGTS 693
>12960
          Length = 550

 Score = 30.8 bits (68), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 23/80 (28%), Positives = 39/80 (48%)
 Frame = +2

Query: 225 NAHGQLVRDLDFNPNKQYYLASCGDDCKVKFWDTRNVTEPVKTLEEHSHWVWSVRYNHSH 284
           N   Q VR + F+ + +Y + +CG D  VK W+       +KT   H H V   + +  +
Sbjct: 164 NCKQQAVRAVRFSVDSRYCM-TCGSDKSVKLWNPHR-ELFLKTYIGHGHEVLDAQGSGDN 337

Query: 285 DQLVLTGSSDSRVILSNMVS 304
            Q + +G  D  V+L ++ S
Sbjct: 338 SQ-ICSGGIDKTVVLFDVAS 394
>04358
          Length = 2430

 Score = 29.6 bits (65), Expect = 2.0,   Method: Compositional matrix adjust.
 Identities = 16/58 (27%), Positives = 24/58 (41%)
 Frame = +1

Query: 206  DTTLRGWDTRSMSQIYCIENAHGQLVRDLDFNPNKQYYLASCGDDCKVKFWDTRNVTE 263
            D  L  WD R    + C E++H   +  + F P  +  L +   D  V  +D    TE
Sbjct: 1639 DAYLLFWDRRKDKLLGCYEDSHHDDITQVHFGPTSEKTLLTGSTDGLVNVFDVMQTTE 1812
>12574
          Length = 521

 Score = 29.6 bits (65), Expect = 2.0,   Method: Compositional matrix adjust.
 Identities = 35/136 (25%), Positives = 66/136 (48%), Gaps = 9/136 (6%)
 Frame = +3

Query: 166 PSSSQAVLASSATLEGRGQLKFT---------AGRWSPHHNCTQVATASDTTLRGWDTRS 216
           P+S+ +   SSAT +    LKFT         A ++SP+ +    ++A D  ++ W    
Sbjct: 105 PASATSGTKSSATQKPTYTLKFTLAGHTKALSAVKFSPNGDWLASSSA-DKLIKIWGAYD 281

Query: 217 MSQIYCIENAHGQLVRDLDFNPNKQYYLASCGDDCKVKFWDTRNVTEPVKTLEEHSHWVW 276
                 I   H   + D+ ++ + +  L S  DD  +K W+  +  + +KTL+ HS++V+
Sbjct: 282 GKFEKTIA-GHKLGLSDVAWSSDSKL-LCSASDDKTLKIWE-FSTGKCMKTLKGHSNYVF 452

Query: 277 SVRYNHSHDQLVLTGS 292
              +N     L+++GS
Sbjct: 453 CCNFN-PQSNLIVSGS 497
>00825
          Length = 1821

 Score = 29.6 bits (65), Expect = 2.1,   Method: Compositional matrix adjust.
 Identities = 22/69 (31%), Positives = 31/69 (44%), Gaps = 4/69 (5%)
 Frame = -2

Query: 204  ASDTTLRGWDTRSMSQIYCIENAHGQLVRDLDFNPNKQYYLASCGDDCKVKFW----DTR 259
            A D  L  W+     Q+ C   AH  +V  +  + + QY+  SCG D  +K W    +  
Sbjct: 1814 ACDGELICWNL-PKQQMACRVQAHDGIVHGMAAHSSGQYFF-SCGSDKTIKQWSLDPEGT 1641

Query: 260  NVTEPVKTL 268
               EPV TL
Sbjct: 1640 IAPEPVNTL 1614
>37142
          Length = 327

 Score = 29.6 bits (65), Expect = 2.1,   Method: Compositional matrix adjust.
 Identities = 18/62 (29%), Positives = 27/62 (43%), Gaps = 6/62 (9%)
 Frame = +2

Query: 227 HGQLVRDLDFNPNKQYYLASCGDDCKVKFWDTRNVTEPV------KTLEEHSHWVWSVRY 280
           H   V+ LDFNP +   LAS   + ++  WD      P+      +  EE S   W+ + 
Sbjct: 101 HTGAVKALDFNPFQTNLLASGASESEIYIWDLNKPDNPMTPGQKSQPPEEVSCVAWNRQV 280

Query: 281 NH 282
            H
Sbjct: 281 QH 286
>19863
          Length = 502

 Score = 29.3 bits (64), Expect = 3.1,   Method: Compositional matrix adjust.
 Identities = 19/71 (26%), Positives = 37/71 (52%)
 Frame = +1

Query: 201 VATASDTTLRGWDTRSMSQIYCIENAHGQLVRDLDFNPNKQYYLASCGDDCKVKFWDTRN 260
           V+ +SD ++  WD  +  Q   ++  H   V D+ F+ + Q +L SC +D  V+ W+   
Sbjct: 19  VSGSSDMSIVVWDVENGVQKLRLQ-GHAGWVNDVHFSQD-QCWLLSCSNDNTVRIWNIEE 192

Query: 261 VTEPVKTLEEH 271
            ++ +  + EH
Sbjct: 193 -SDQIPIVMEH 222
>21763
          Length = 923

 Score = 28.5 bits (62), Expect = 4.9,   Method: Compositional matrix adjust.
 Identities = 17/52 (32%), Positives = 26/52 (50%)
 Frame = +1

Query: 250 DCKVKFWDTRNVTEPVKTLEEHSHWVWSVRYNHSHDQLVLTGSSDSRVILSN 301
           DCK  ++D    T+P K L  H   V  V Y+H +  L  + S D  +I+ +
Sbjct: 505 DCKSCWFDLDLSTKPYKILRHHKRAVRHVSYHHRYP-LFASASDDGSIIVCH 657
>20271
          Length = 567

 Score = 28.1 bits (61), Expect = 6.0,   Method: Compositional matrix adjust.
 Identities = 11/33 (33%), Positives = 20/33 (60%)
 Frame = -1

Query: 339 IATYEEHEDSVYAVDWASADPWLFASLSYDGRL 371
           + ++E++ D V  V W+  +P LF+ +   GRL
Sbjct: 162 VCSFEDNSDYVSDVQWSPTNPALFSCVDIMGRL 64
>13890
          Length = 630

 Score = 27.7 bits (60), Expect = 9.2,   Method: Compositional matrix adjust.
 Identities = 36/160 (22%), Positives = 65/160 (40%), Gaps = 24/160 (15%)
 Frame = +1

Query: 236 FNPNKQYYLASCGDDCKVKFWDTRNVTEPVKTL--EEHSHWVWSVRYNHSHDQLVLTGSS 293
           F+P   + +A+   DC ++ WD R+   PV+ L  +E    V  V ++H   ++   G  
Sbjct: 4   FHPVTPHLVATGTTDC-IQVWDVRHPEVPVRVLTHKEQLGQVQDVMFSHDGQEVFSCGDV 180

Query: 294 DSR---------------VILSNMV----SISSEPFGHLVDDDDVSDPEEHHAE--KSKE 332
            SR               VILSN +       +    H      ++  +  +     ++ 
Sbjct: 181 VSRESSDRSIMAWDFRTGVILSNQIFQERYTVTRLMLHPYQSQFLAQTQAGYIAVFSTQR 360

Query: 333 PLQDNVIATYEEHEDSVYAVDWA-SADPWLFASLSYDGRL 371
           P + N    +E H+ + Y +  + S D  +  S S DG+L
Sbjct: 361 PYKMNKNKRFEGHKTAGYNIGASLSQDGSIVYSGSSDGKL 480
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|46909607|ref|NP_631883.2| O-linked
N-acetylglucosamine transferase [Mus musculus]
         (1046 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

20328                                                                 368   e-102
33552                                                                  77   3e-14
18426                                                                  63   5e-10
18279                                                                  56   1e-07
30337                                                                  49   7e-06
04645                                                                  43   7e-04
13793                                                                  43   8e-04
28154                                                                  42   0.001
27726                                                                  40   0.006
17595                                                                  39   0.007
35264                                                                  39   0.013
10994                                                                  37   0.052
35348                                                                  35   0.21 
31632                                                                  30   4.1  
00599                                                                  30   4.1  
>20328
          Length = 1143

 Score =  368 bits (945), Expect = e-102,   Method: Compositional matrix adjust.
 Identities = 175/277 (63%), Positives = 208/277 (75%)
 Frame = -2

Query: 762  GDNPDSSNTALNMPVIPMNTIAEAVIEMINRGQIQITINGFSISNGLATTQINNKAATGE 821
            G+  + + T + +PV  + T+      MI   Q Q  +    + NGL T Q NNKAATGE
Sbjct: 1127 GEVGEVTTTVVELPVAMVQTLQT----MITSSQPQCNVGTVLVQNGLTTNQTNNKAATGE 960

Query: 822  EVPRTIIVTTRSQYGLPEDAIVYCNFNQLYKIDPSTLQMWANILKRVPNSVLWLLRFPAV 881
            EVPR ++++ R+QYGLPEDA+VYCNFNQLYKI+P+TL MW  ILK+VPN VLWLLRFPAV
Sbjct: 959  EVPRCVVLSARAQYGLPEDAVVYCNFNQLYKIEPATLDMWVQILKQVPNGVLWLLRFPAV 780

Query: 882  GEPNIQQYAQNMGLPQNRIIFSPVAPKEEHVRRGQLADVCLDTPLCNGHTTGMDVLWAGT 941
            GE NI Q A + GLP  RI+FS VAPKEEHVRRGQLADVCLDTPLCNGHTTGMDVLWAGT
Sbjct: 779  GETNITQAATSFGLPAGRIVFSNVAPKEEHVRRGQLADVCLDTPLCNGHTTGMDVLWAGT 600

Query: 942  PMVTMPGETLASRVAASQLTCLGCLELIAKSRQEYEDIAVKLGTDLEYLKKIRGKVWKQR 1001
            PMVT PGETLASRVA+SQL  LGC EL+A SR++Y  IAV+LGTDLEYL+ ++ KV   R
Sbjct: 599  PMVTFPGETLASRVASSQLHSLGCPELVANSREDYIRIAVQLGTDLEYLRGMQAKVSLAR 420

Query: 1002 ISSPLFNTKQYTMELERLYLQMWEHYAAGNKPDHMIK 1038
             SSPLFNTK Y   LE L+ QMW+ +     PDH+ +
Sbjct: 419  KSSPLFNTKTYATNLETLFYQMWKQHERAGVPDHLTE 309
>33552
          Length = 373

 Score = 77.4 bits (189), Expect = 3e-14,   Method: Compositional matrix adjust.
 Identities = 37/73 (50%), Positives = 49/73 (67%)
 Frame = -1

Query: 970  AKSRQEYEDIAVKLGTDLEYLKKIRGKVWKQRISSPLFNTKQYTMELERLYLQMWEHYAA 1029
            A+SRQ+Y DIAVKLGT+L YL+ ++ KV   R +SPLFNT+ YT  LE LY +MW     
Sbjct: 373  AQSRQDYVDIAVKLGTNLPYLRGMQAKVNLARSTSPLFNTRTYTQNLEDLYCRMWNQKQQ 194

Query: 1030 GNKPDHMIKPVEV 1042
             ++ DH+    EV
Sbjct: 193  QDEADHLTNNTEV 155
>18426
          Length = 451

 Score = 63.2 bits (152), Expect = 5e-10,   Method: Compositional matrix adjust.
 Identities = 26/52 (50%), Positives = 36/52 (69%)
 Frame = +2

Query: 985  TDLEYLKKIRGKVWKQRISSPLFNTKQYTMELERLYLQMWEHYAAGNKPDHM 1036
            T+ EYLK +R KVWK R+ SPLF+  QY   LE L+L+MW+ +    +PDH+
Sbjct: 2    TEREYLKALRAKVWKARVDSPLFDCSQYAKGLENLFLRMWDRFHNNEEPDHI 157
>18279
          Length = 706

 Score = 55.8 bits (133), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 57/219 (26%), Positives = 91/219 (41%), Gaps = 16/219 (7%)
 Frame = +3

Query: 171 GRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDAY-- 228
           G++ EA   + +A++   +   AWS +G +  A+ E       FE+ +       DAY  
Sbjct: 6   GQIYEASDWFKEALQINQDHPDAWSLIGSLHLAKQEWGPGQKKFERILQRTQTKDDAYSL 185

Query: 229 INLGNVL------------KEARIFDRAVAAYLRALSLSPNHAVVHGNLACVYYEQGLID 276
           I LGNV             KE R  DRA+A Y + L   P +      + CV   +G I+
Sbjct: 186 IALGNVWLQTLHQPMRDKDKEKRHQDRALAMYKQVLRNDPKNIWAANGIGCVLAHKGCIN 365

Query: 277 LAIDTYRRAIELQPHFPDAYCNLANALKEKGSVAEAEDCYNTAL-RLCPTH-ADSLNNLA 334
            + D + +  E    F D + N+A+   E+     A   Y  AL +    H  + +  LA
Sbjct: 366 ESRDVFAQVREATADFCDVWLNIAHIYVEQRQFVAAVQMYENALKKFSRNHNVEVMVYLA 545

Query: 335 NIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQ 373
               + G +++      KA  V P       N+A V Q+
Sbjct: 546 RAYYKCGKLQDCKTTLLKARHVAPHDTVLLYNIALVQQK 662
>30337
          Length = 493

 Score = 49.3 bits (116), Expect = 7e-06,   Method: Compositional matrix adjust.
 Identities = 30/101 (29%), Positives = 49/101 (48%)
 Frame = -1

Query: 164 GNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPN 223
           GN L A  + E+A  CY KAI   PN A  ++N    +       LA    ++A+ LD N
Sbjct: 310 GNKLFAARKYEDAIHCYTKAIMKNPNTATYFTNRALCYIKLRNWELASQDCQRALELDRN 131

Query: 224 FLDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGN 264
            +  +  LG  L E  ++D A+   ++A  L+ +  +  G+
Sbjct: 130 LVKGHFFLGQALVELAMYDEAITHLMKAHDLAKDQKLNFGD 8
>04645
          Length = 1075

 Score = 42.7 bits (99), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 32/132 (24%), Positives = 63/132 (47%)
 Frame = +3

Query: 330 LNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIR 389
           L+N   I  +  ++ E   +  +  +   + A+ + N A     +G+L++A+  + +AI+
Sbjct: 351 LDNTGVITDDDEDMPEYADVNIEVTDDMIDQASDNRNQAMDAMAEGRLEDAIGFFTDAIK 530

Query: 390 ISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAI 449
            +PT A  Y+  G+   +M   + A+   ++AI++NP  A  +      HK  G+  E+ 
Sbjct: 531 SNPTSALLYAKRGSAYLKMGKPKKAIHDCSKAIELNPDSAQGYKWRGKAHKLLGHWEESY 710

Query: 450 ASYRTALKLKPD 461
                A KL  D
Sbjct: 711 HDLTLACKLDYD 746

 Score = 40.0 bits (92), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 22/68 (32%), Positives = 34/68 (50%)
 Frame = +3

Query: 169 ALGRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDAY 228
           A GRLE+A   +  AI++ P  A+ ++  G  +   G+   AIH   KA+ L+P+    Y
Sbjct: 480 AEGRLEDAIGFFTDAIKSNPTSALLYAKRGSAYLKMGKPKKAIHDCSKAIELNPDSAQGY 659

Query: 229 INLGNVLK 236
              G   K
Sbjct: 660 KWRGKAHK 683

 Score = 38.9 bits (89), Expect = 0.010,   Method: Compositional matrix adjust.
 Identities = 22/57 (38%), Positives = 31/57 (54%)
 Frame = +3

Query: 70  RLDRSAHFSTLAIKQNPLLAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDGY 126
           RL+ +  F T AIK NP  A  Y+  G+ Y + G+ ++AI     A+ L PD   GY
Sbjct: 489 RLEDAIGFFTDAIKSNPTSALLYAKRGSAYLKMGKPKKAIHDCSKAIELNPDSAQGY 659
>13793
          Length = 754

 Score = 42.7 bits (99), Expect = 8e-04,   Method: Compositional matrix adjust.
 Identities = 35/102 (34%), Positives = 49/102 (48%), Gaps = 3/102 (2%)
 Frame = +1

Query: 170 LGRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQGEI--WL-AIHHFEKAVTLDPNFLD 226
           LGRLE+A      A++  P+ A  W N   V N QG++  W  +   F  A+ LD     
Sbjct: 256 LGRLEQAVKMADVALKHLPSSASLWFN---VANVQGKLERWTDSEQSFLNAIRLDAREAR 426

Query: 227 AYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGNLACV 268
            ++NLG +       D+A  AY  AL  SPN   +  NLA +
Sbjct: 427 YHLNLGVLYHRWGKLDQAEKAYQVALQYSPNDRTIQDNLAML 552

 Score = 40.8 bits (94), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 26/99 (26%), Positives = 52/99 (52%)
 Frame = +1

Query: 70  RLDRSAHFSTLAIKQNPLLAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDGYINL 129
           RL+++   + +A+K  P  A  + N+ NV  +  +  ++ + + +A+RL       ++NL
Sbjct: 262 RLEQAVKMADVALKHLPSSASLWFNVANVQGKLERWTDSEQSFLNAIRLDAREARYHLNL 441

Query: 130 AAALVAAGDMEGAVQAYVSALQYNPDLYCVRSDLGNLLK 168
                  G ++ A +AY  ALQY+P+   ++ +L  L K
Sbjct: 442 GVLYHRWGKLDQAEKAYQVALQYSPNDRTIQDNLAMLAK 558

 Score = 36.2 bits (82), Expect = 0.080,   Method: Compositional matrix adjust.
 Identities = 30/103 (29%), Positives = 50/103 (48%), Gaps = 3/103 (2%)
 Frame = +1

Query: 341 GNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQ---EALMHYKEAIRISPTFADA 397
           G +E+AV++   AL+  P  A+   N+A+V   QGKL+   ++   +  AIR+    A  
Sbjct: 259 GRLEQAVKMADVALKHLPSSASLWFNVANV---QGKLERWTDSEQSFLNAIRLDAREARY 429

Query: 398 YSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHK 440
           + N+G        +  A + Y  A+Q +P       NLA + K
Sbjct: 430 HLNLGVLYHRWGKLDQAEKAYQVALQYSPNDRTIQDNLAMLAK 558

 Score = 30.0 bits (66), Expect(2) = 0.16,   Method: Compositional matrix adjust.
 Identities = 22/93 (23%), Positives = 45/93 (48%)
 Frame = +1

Query: 131 AALVAAGDMEGAVQAYVSALQYNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQPNF 190
           ++ +  G +E AV+    AL++ P    +  ++ N+   L R  +++  +L AI      
Sbjct: 241 SSWIILGRLEQAVKMADVALKHLPSSASLWFNVANVQGKLERWTDSEQSFLNAIRLDARE 420

Query: 191 AVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPN 223
           A    NLG +++  G++  A   ++ A+   PN
Sbjct: 421 ARYHLNLGVLYHRWGKLDQAEKAYQVALQYSPN 519

 Score = 23.5 bits (49), Expect(2) = 0.16,   Method: Composition-based stats.
 Identities = 10/31 (32%), Positives = 18/31 (58%)
 Frame = +3

Query: 98  VYKERGQLQEAIEHYRHALRLKPDFIDGYIN 128
           +Y E  + QEA+  + +A  LKP  ++ + N
Sbjct: 141 LYLEEKRHQEALTAWHNATLLKPQHVNAWSN 233

 Score = 31.6 bits (70), Expect(2) = 0.17,   Method: Compositional matrix adjust.
 Identities = 19/46 (41%), Positives = 21/46 (45%)
 Frame = +2

Query: 358 PEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGN 403
           P FAAA  NL  V  Q  K  EA   Y   I     + D Y N+GN
Sbjct: 2   PIFAAAWMNLGIVQVQLKKYAEAERSYYTTISHRRNYPDCYYNLGN 139

 Score = 22.3 bits (46), Expect(2) = 0.17,   Method: Compositional matrix adjust.
 Identities = 11/42 (26%), Positives = 20/42 (47%)
 Frame = +1

Query: 443 GNIPEAIASYRTALKLKPDFPDAYCNLAHCLQIVCDWTDYDE 484
           G + +A+     ALK  P     + N+A+    +  WTD ++
Sbjct: 259 GRLEQAVKMADVALKHLPSSASLWFNVANVQGKLERWTDSEQ 384

 Score = 30.0 bits (66), Expect = 4.5,   Method: Compositional matrix adjust.
 Identities = 17/48 (35%), Positives = 23/48 (47%)
 Frame = +2

Query: 188 PNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVL 235
           P FA AW NLG V     +   A   +   ++   N+ D Y NLGN +
Sbjct: 2   PIFAAAWMNLGIVQVQLKKYAEAERSYYTTISHRRNYPDCYYNLGNFV 145
>28154
          Length = 374

 Score = 42.4 bits (98), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 22/74 (29%), Positives = 36/74 (48%)
 Frame = +1

Query: 159 VRSDLGNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAV 218
           V+ +LG L    G   +A  C+  A++ +P  A+ W+ LG      G    A+  +  A+
Sbjct: 100 VQCNLGVLFNLSGEYNKAVDCFQAALQARPKDALLWNKLGATLANGGRSEEAVDAYHNAL 279

Query: 219 TLDPNFLDAYINLG 232
            L P F+ +  NLG
Sbjct: 280 QLSPGFIRSRYNLG 321

 Score = 41.6 bits (96), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 26/75 (34%), Positives = 32/75 (42%)
 Frame = +1

Query: 294 DAYCNLANALKEKGSVAEAEDCYNTALRLCPTHADSLNNLANIKREQGNIEEAVRLYRKA 353
           D  CNL       G   +A DC+  AL+  P  A   N L       G  EEAV  Y  A
Sbjct: 97  DVQCNLGVLFNLSGEYNKAVDCFQAALQARPKDALLWNKLGATLANGGRSEEAVDAYHNA 276

Query: 354 LEVFPEFAAAHSNLA 368
           L++ P F  +  NL 
Sbjct: 277 LQLSPGFIRSRYNLG 321

 Score = 39.3 bits (90), Expect = 0.009,   Method: Compositional matrix adjust.
 Identities = 26/96 (27%), Positives = 48/96 (50%), Gaps = 4/96 (4%)
 Frame = +1

Query: 311 EAEDCYNTALRLC----PTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSN 366
           E ++ Y +A+++        AD   NL  +    G   +AV  ++ AL+  P+ A   + 
Sbjct: 34  EVQNLYLSAVQMAAPQESVDADVQCNLGVLFNLSGEYNKAVDCFQAALQARPKDALLWNK 213

Query: 367 LASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMG 402
           L + L   G+ +EA+  Y  A+++SP F  +  N+G
Sbjct: 214 LGATLANGGRSEEAVDAYHNALQLSPGFIRSRYNLG 321

 Score = 38.5 bits (88), Expect = 0.013,   Method: Compositional matrix adjust.
 Identities = 34/106 (32%), Positives = 46/106 (43%), Gaps = 11/106 (10%)
 Frame = +1

Query: 174 EEAKACYLKAIE-TQPNFAV---AWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYI 229
           EE +  YL A++   P  +V      NLG +FN  GE   A+  F+ A+   P     + 
Sbjct: 31  EEVQNLYLSAVQMAAPQESVDADVQCNLGVLFNLSGEYNKAVDCFQAALQARPKDALLWN 210

Query: 230 NLGNVLKEARIFDRAVAAYLRALSLSP-------NHAVVHGNLACV 268
            LG  L      + AV AY  AL LSP       N  +   NL C+
Sbjct: 211 KLGATLANGGRSEEAVDAYHNALQLSPGFIRSRYNLGIACINLGCI 348

 Score = 37.7 bits (86), Expect = 0.025,   Method: Compositional matrix adjust.
 Identities = 27/84 (32%), Positives = 37/84 (44%), Gaps = 7/84 (8%)
 Frame = +1

Query: 124 DGYINLAAALVAAGDMEGAVQAYVSALQYNPDLYCVRSDLGNLLKALGRLEEAKACYLKA 183
           D   NL      +G+   AV  + +ALQ  P    + + LG  L   GR EEA   Y  A
Sbjct: 97  DVQCNLGVLFNLSGEYNKAVDCFQAALQARPKDALLWNKLGATLANGGRSEEAVDAYHNA 276

Query: 184 IETQPNF-------AVAWSNLGCV 200
           ++  P F        +A  NLGC+
Sbjct: 277 LQLSPGFIRSRYNLGIACINLGCI 348

 Score = 36.2 bits (82), Expect = 0.080,   Method: Compositional matrix adjust.
 Identities = 27/91 (29%), Positives = 43/91 (47%), Gaps = 4/91 (4%)
 Frame = +1

Query: 248 YLRALSLS-PNHAV---VHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANAL 303
           YL A+ ++ P  +V   V  NL  ++   G  + A+D ++ A++ +P     +  L   L
Sbjct: 49  YLSAVQMAAPQESVDADVQCNLGVLFNLSGEYNKAVDCFQAALQARPKDALLWNKLGATL 228

Query: 304 KEKGSVAEAEDCYNTALRLCPTHADSLNNLA 334
              G   EA D Y+ AL+L P    S  NL 
Sbjct: 229 ANGGRSEEAVDAYHNALQLSPGFIRSRYNLG 321
>27726
          Length = 366

 Score = 39.7 bits (91), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 19/57 (33%), Positives = 31/57 (54%)
 Frame = -2

Query: 402 GNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKL 458
            N L +++    A   Y R I+I+P     H+NL  ++     IPEA+ SY+TA+ +
Sbjct: 350 ANVLGKLKQYMEAETLYKRVIEIDPRNMLYHTNLGVLYHRWEKIPEAMESYQTAISI 180

 Score = 33.5 bits (75), Expect = 0.50,   Method: Compositional matrix adjust.
 Identities = 22/76 (28%), Positives = 39/76 (51%), Gaps = 1/76 (1%)
 Frame = -2

Query: 334 ANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPT 393
           AN+  +     EA  LY++ +E+ P     H+NL  +  +  K+ EA+  Y+ AI I+ +
Sbjct: 350 ANVLGKLKQYMEAETLYKRVIEIDPRNMLYHTNLGVLYHRWEKIPEAMESYQTAISINFS 171

Query: 394 FA-DAYSNMGNTLKEM 408
            A  A  N+   +K +
Sbjct: 170 RATTARDNLNKLMKRL 123
>17595
          Length = 483

 Score = 39.3 bits (90), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 26/103 (25%), Positives = 46/103 (44%)
 Frame = -2

Query: 283 RRAIELQPHFPDAYCNLANALKEKGSVAEAEDCYNTALRLCPTHADSLNNLANIKREQGN 342
           +RA+   PH PD Y        + G   +A   Y  A+ L    + ++ N A   RE G 
Sbjct: 326 KRALTYHPHLPDLYNFYGIVFHKTGQYEQAVASYERAVSLDNKFSHAMTNAAASLRELGR 147

Query: 343 IEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYK 385
             EA    ++A++   +  A    L  + Q+ G+ Q+A+  ++
Sbjct: 146 HREAELFLKRAVDTTADLDAM-GQLGRLYQRMGRTQDAVNMFR 21
>35264
          Length = 867

 Score = 38.5 bits (88), Expect = 0.013,   Method: Compositional matrix adjust.
 Identities = 24/86 (27%), Positives = 40/86 (46%)
 Frame = +3

Query: 373 QQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAH 432
           Q  K +EAL  Y  AI + P+ A  Y N   T   ++  +  L+   +A+Q++P F   +
Sbjct: 75  QAAKYKEALECYTCAINLCPSCAAYYGNRAATYMMLKKYREGLKDAQQAVQLDPTFVKGY 254

Query: 433 SNLASIHKDSGNIPEAIASYRTALKL 458
                 H   GN   A +++   L+L
Sbjct: 255 IREGKCHLMLGNSMAASSNFNRVLEL 332

 Score = 31.6 bits (70), Expect = 1.7,   Method: Compositional matrix adjust.
 Identities = 16/49 (32%), Positives = 24/49 (48%)
 Frame = +3

Query: 79  TLAIKQNPLLAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDGYI 127
           T AI   P  A  Y N    Y    + +E ++  + A++L P F+ GYI
Sbjct: 111 TCAINLCPSCAAYYGNRAATYMMLKKYREGLKDAQQAVQLDPTFVKGYI 257

 Score = 30.0 bits (66), Expect = 4.8,   Method: Compositional matrix adjust.
 Identities = 25/128 (19%), Positives = 46/128 (35%)
 Frame = +3

Query: 311 EAEDCYNTALRLCPTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASV 370
           EA +CY  A+ LCP+                                   AA + N A+ 
Sbjct: 93  EALECYTCAINLCPS----------------------------------CAAYYGNRAAT 170

Query: 371 LQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFAD 430
                K +E L   ++A+++ PTF   Y   G     + +   A   + R ++++   + 
Sbjct: 171 YMMLKKYREGLKDAQQAVQLDPTFVKGYIREGKCHLMLGNSMAASSNFNRVLELDAGNST 350

Query: 431 AHSNLASI 438
           A + L  +
Sbjct: 351 AVTELKRV 374
>10994
          Length = 2182

 Score = 36.6 bits (83), Expect = 0.052,   Method: Compositional matrix adjust.
 Identities = 31/115 (26%), Positives = 48/115 (41%), Gaps = 8/115 (6%)
 Frame = -3

Query: 187  QPNFAVAWSNL-GCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAV 245
            Q N  V +S + G     +G+   AI H   A+ +DP   +A +  G V      + +A+
Sbjct: 1670 QTNKQVHYSVVQGVEMVKKGQHLEAIQHLNLALKIDPLHTEALVARGAVYANNASYGKAI 1491

Query: 246  AAYLRALSLSPNHAVVHGNL-------ACVYYEQGLIDLAIDTYRRAIELQPHFP 293
              + +AL   P H      L       A  Y E+G I  AI+ Y+   E +   P
Sbjct: 1490 EDFEKALEGDPKHVNAKKYLMETKIASARRYEEEGNIXEAINNYKSRTEARRSVP 1326

 Score = 36.2 bits (82), Expect = 0.075,   Method: Compositional matrix adjust.
 Identities = 23/98 (23%), Positives = 47/98 (47%), Gaps = 7/98 (7%)
 Frame = -3

Query: 373  QQGKLQEALMHYKEAIRISPTFADA-------YSNMGNTLKEMQDVQGALQCYTRAIQIN 425
            ++G+  EA+ H   A++I P   +A       Y+N  +  K ++D + AL+   + +   
Sbjct: 1619 KKGQHLEAIQHLNLALKIDPLHTEALVARGAVYANNASYGKAIEDFEKALEGDPKHVNAK 1440

Query: 426  PAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFP 463
                +     A  +++ GNI EAI +Y++  + +   P
Sbjct: 1439 KYLMETKIASARRYEEEGNIXEAINNYKSRTEARRSVP 1326

 Score = 31.2 bits (69), Expect = 2.2,   Method: Compositional matrix adjust.
 Identities = 28/98 (28%), Positives = 45/98 (45%), Gaps = 10/98 (10%)
 Frame = -3

Query: 305  EKGSVAEAEDCYNTALRLCPTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAH 364
            +KG   EA    N AL++ P H ++L     +     +  +A+  + KALE  P+   A 
Sbjct: 1619 KKGQHLEAIQHLNLALKIDPLHTEALVARGAVYANNASYGKAIEDFEKALEGDPKHVNAK 1440

Query: 365  SNL-------ASVLQQQGKLQEALMHYK---EAIRISP 392
              L       A   +++G + EA+ +YK   EA R  P
Sbjct: 1439 KYLMETKIASARRYEEEGNIXEAINNYKSRTEARRSVP 1326
>35348
          Length = 627

 Score = 34.7 bits (78), Expect = 0.21,   Method: Composition-based stats.
 Identities = 24/111 (21%), Positives = 55/111 (49%), Gaps = 5/111 (4%)
 Frame = -2

Query: 305 EKGSVAEAEDCYNTALRLCP-----THADSLNNLANIKREQGNIEEAVRLYRKALEVFPE 359
           + G  AEA + Y+  L +CP       +  L+N A  + ++ + ++AV    K++++ P 
Sbjct: 548 KSGQYAEALELYSEGLDICPLKYVQQRSVMLSNRAACRIKKEDYQKAVGDCTKSIDLNPA 369

Query: 360 FAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQD 410
           +  A+   A   ++  KL +AL  +++ + +  +  D+        KE+++
Sbjct: 368 YIKAYFRRADAYEKLEKLDDALKDHRQVVEMDRSQIDSIQACLRLEKEIEE 216
>31632
          Length = 390

 Score = 30.4 bits (67), Expect = 4.1,   Method: Composition-based stats.
 Identities = 18/76 (23%), Positives = 35/76 (46%)
 Frame = +1

Query: 642 YTKGARNELFALRPAPIQAMWLGYPGTSGALFMDYIITDQETSPAEVAEQYSEKLAYMPH 701
           + K  R++ FA +    +  +  +PG +   +MD  + +QE+          ++ A   H
Sbjct: 118 WKKSERHDHFASKNRLEKRKYTLHPGVTD--YMDRFLDEQESGALPGTLPGRDRSASPIH 291

Query: 702 TFFIGDHANMFPHLKK 717
           +   GDH    PHL++
Sbjct: 292 SLMYGDHKRSVPHLRQ 339
>00599
          Length = 1505

 Score = 30.4 bits (67), Expect = 4.1,   Method: Compositional matrix adjust.
 Identities = 12/25 (48%), Positives = 17/25 (68%)
 Frame = +2

Query: 445 IPEAIASYRTALKLKPDFPDAYCNL 469
           IP+A+AS+R   K +PD  D+ C L
Sbjct: 68  IPDAVASFRDTNKCRPDTADSTCYL 142
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6753540|ref|NP_034104.1| casein kinase 2, alpha prime
polypeptide [Mus musculus]
         (350 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

03508                                                                 369   e-102
00638                                                                 131   2e-43
01060                                                                 114   4e-26
12704                                                                 107   8e-24
14126                                                                 102   3e-22
04138                                                                  96   2e-20
01707                                                                  95   4e-20
29581                                                                  94   7e-20
04591                                                                  94   1e-19
32000                                                                  87   1e-17
01756                                                                  82   4e-16
21079                                                                  73   2e-13
15910                                                                  72   3e-13
23319                                                                  71   6e-13
26560                                                                  70   1e-12
01392                                                                  68   5e-12
00300                                                                  65   6e-11
01966                                                                  64   9e-11
12786                                                                  64   1e-10
12721                                                                  63   2e-10
03294                                                                  60   2e-09
14420                                                                  59   2e-09
31885                                                                  59   4e-09
30755                                                                  59   4e-09
13212                                                                  57   8e-09
19761                                                                  57   1e-08
18287                                                                  57   1e-08
18921                                                                  57   1e-08
27405                                                                  57   1e-08
26711                                                                  57   2e-08
13592                                                                  55   5e-08
28638                                                                  55   6e-08
09606                                                                  54   8e-08
03240                                                                  54   1e-07
18484                                                                  54   1e-07
19094                                                                  53   2e-07
21433                                                                  52   3e-07
18401                                                                  50   1e-06
07940                                                                  46   3e-05
13078                                                                  45   4e-05
37602                                                                  45   4e-05
31489                                                                  44   1e-04
13066                                                                  43   2e-04
11185                                                                  42   3e-04
01718                                                                  42   3e-04
05084                                                                  42   3e-04
26009                                                                  42   4e-04
17975                                                                  42   5e-04
00715                                                                  41   7e-04
00392                                                                  40   0.001
12453                                                                  37   0.009
14116                                                                  37   0.009
27546                                                                  37   0.009
32359                                                                  28   0.010
06358                                                                  37   0.013
01106                                                                  36   0.019
18481                                                                  36   0.019
21800                                                                  35   0.031
28157                                                                  35   0.035
02638                                                                  35   0.052
20773                                                                  33   0.13 
15931                                                                  33   0.19 
35032                                                                  33   0.24 
19301                                                                  33   0.24 
26909                                                                  32   0.27 
29590                                                                  30   0.98 
14104                                                                  30   1.0  
37063                                                                  30   1.1  
17644                                                                  29   2.8  
36481                                                                  29   3.1  
18663                                                                  29   3.1  
29360                                                                  29   3.6  
37603                                                                  28   6.3  
20152                                                                  28   7.0  
12045                                                                  28   7.0  
>03508
          Length = 1463

 Score =  369 bits (946), Expect = e-102,   Method: Compositional matrix adjust.
 Identities = 173/234 (73%), Positives = 192/234 (82%)
 Frame = +1

Query: 1   MPGPAAGSRARVYAEVNSLRSREYWDYEAHVPSWGNQDDYQLVRKLGRGKYSEVFEAINI 60
           MP P   SRARVYA+VN+ ++REYWDYE+HV  WGNQDDYQ+VRKLGRGKYSEVFEAIN+
Sbjct: 487 MPLP---SRARVYADVNTHKAREYWDYESHVVEWGNQDDYQIVRKLGRGKYSEVFEAINV 657

Query: 61  TNNEXXXXXXXXXXXXXXXXXXXXXXXNLRGGTNIIKLIDTVKDPVSKTPALVFEYINNT 120
           TNNE                       NLRGGTN+I L+  VKDPVS+TPAL+FE++NNT
Sbjct: 658 TNNEKCVIKILKPVKKKKIKREIKILENLRGGTNVITLLAIVKDPVSRTPALIFEHVNNT 837

Query: 121 DFKQLYQILTDFDIRFYMYELLKALDYCHSKGIMHRDVKPHNVMIDHQQKKLRLIDWGLA 180
           DFKQLYQ  TD+DIRFY+YEL+KALD+CHS GIMHRDVKPHNVMIDH+ KKLRLIDWGLA
Sbjct: 838 DFKQLYQTFTDYDIRFYLYELMKALDFCHSMGIMHRDVKPHNVMIDHENKKLRLIDWGLA 1017

Query: 181 EFYHPAQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFF 234
           EFYHP  EYNVRVASRYFKGPELL+DYQMYDYSLDMWSLGCM ASMIFRKEP  
Sbjct: 1018EFYHPGMEYNVRVASRYFKGPELLLDYQMYDYSLDMWSLGCMFASMIFRKEPLL 1179

 Score =  179 bits (454), Expect = 2e-45,   Method: Compositional matrix adjust.
 Identities = 83/115 (72%), Positives = 96/115 (83%), Gaps = 3/115 (2%)
 Frame = +2

Query: 217  WSLGCMLASM---IFRKEPFFHGQDNYDQLVRIAKVLGTDELYGYLKKYHIDLDPHFNDI 273
            W+ G   A +      K PFFHG DNYDQLVRIAKVLGTD+LYGY++KY IDLDP FNDI
Sbjct: 1118 WTCGVWAACLPA*SSGKSPFFHGHDNYDQLVRIAKVLGTDDLYGYIEKYQIDLDPRFNDI 1297

Query: 274  LGQHSRKRWENFIHSENRHLVSPEALDLLDKLLRYDHQQRLTAKEAMEHPYFYPV 328
            LG+HSRKRWE F+HSEN+HL+SPEALD LDKLLRYDH +RLTA+EAM+HPYF P+
Sbjct: 1298 LGRHSRKRWERFVHSENQHLISPEALDFLDKLLRYDHNERLTAREAMDHPYFXPI 1462
>00638
          Length = 1595

 Score =  131 bits (330), Expect(2) = 2e-43,   Method: Compositional matrix adjust.
 Identities = 57/79 (72%), Positives = 70/79 (88%)
 Frame = +2

Query: 88  NLRGGTNIIKLIDTVKDPVSKTPALVFEYINNTDFKQLYQILTDFDIRFYMYELLKALDY 147
           NLRGGTN+I L+  VKDPVS+TPAL+FE++NNTDFKQLYQ  TD+DIRFY+YEL+KALD+
Sbjct: 284 NLRGGTNVITLLAIVKDPVSRTPALIFEHVNNTDFKQLYQTFTDYDIRFYLYELMKALDF 463

Query: 148 CHSKGIMHRDVKPHNVMID 166
           CHS GIMHRDVKP   +++
Sbjct: 464 CHSMGIMHRDVKPSPPLVN 520

 Score = 62.4 bits (150), Expect(2) = 2e-43,   Method: Compositional matrix adjust.
 Identities = 29/37 (78%), Positives = 32/37 (86%)
 Frame = +1

Query: 28  EAHVPSWGNQDDYQLVRKLGRGKYSEVFEAINITNNE 64
           E  + S  NQDDYQ+VRKLGRGKYSEVFEAIN+TNNE
Sbjct: 103 EVRLLSRRNQDDYQIVRKLGRGKYSEVFEAINVTNNE 213
>01060
          Length = 1800

 Score =  114 bits (286), Expect = 4e-26,   Method: Compositional matrix adjust.
 Identities = 73/258 (28%), Positives = 135/258 (52%), Gaps = 10/258 (3%)
 Frame = +1

Query: 93  TNIIKLIDTVKDPVSKTPALVFEYINNTDFKQLYQ------ILTDFDIRFYMYELLKALD 146
           TNI+ L D + +   +   LVFE+++  D K          +L    ++ Y+++++  + 
Sbjct: 250 TNIVCLEDVIME--DERLFLVFEFLS-MDLKMYIDKFPEGVVLDRRLVKSYVFQIVTGIX 420

Query: 147 YCHSKGIMHRDVKPHNVMIDHQQKKLRLIDWGLAE-FYHPAQEYNVRVASRYFKGPELLV 205
           +CH + I+HRD+KP N++I+H    +++ D+G+A  F  P + Y   V + +++ PE+L+
Sbjct: 421 FCHQRRIVHRDLKPQNLLINH-TGAIKIADFGMARTFALPVRAYTHEVVTLWYRAPEILM 597

Query: 206 DYQMYDYSLDMWSLGCMLASMIFRKEPFFHGQDNYDQLVRIAKVLGTDELYGYLKKYHID 265
               Y   +D+WS+G + A M+ R  P F G    DQL +I +++GT     + + + + 
Sbjct: 598 GASKYSTPVDVWSIGTIFADMLIRT-PIFKGDSEIDQLFKIFRIIGTPTEQTWPEFHKL- 771

Query: 266 LDPHFNDILGQHSRKRWENFIHSENRHLVSPEALDLLDKLLRYDHQQRLTAKEAMEHPYF 325
             P FN +        W+    SE    +    LDL+++ L+ D  QR++ K+ ++H YF
Sbjct: 772 --PAFNGMF-----PLWKEGKLSETLTDLDSLGLDLIERTLKCDPAQRISCKKMLQHAYF 930

Query: 326 YPV---VKEQSQPCAENT 340
             V   VK    P  E++
Sbjct: 931 LNVDTSVKPVDVPSPEHS 984
>12704
          Length = 641

 Score =  107 bits (266), Expect = 8e-24,   Method: Compositional matrix adjust.
 Identities = 51/64 (79%), Positives = 56/64 (87%)
 Frame = +3

Query: 1   MPGPAAGSRARVYAEVNSLRSREYWDYEAHVPSWGNQDDYQLVRKLGRGKYSEVFEAINI 60
           MP P   SRARVYA+VN+ + REYWDYE+HV  WGNQDDYQ+VRKLGRGKYSEVFEAINI
Sbjct: 429 MPLP---SRARVYADVNTHKPREYWDYESHVVEWGNQDDYQIVRKLGRGKYSEVFEAINI 599

Query: 61  TNNE 64
           TNNE
Sbjct: 600 TNNE 611
>14126
          Length = 1265

 Score =  102 bits (254), Expect = 3e-22,   Method: Compositional matrix adjust.
 Identities = 67/239 (28%), Positives = 122/239 (51%), Gaps = 7/239 (2%)
 Frame = +3

Query: 94  NIIKLIDTVKDPVSKTPA---LVFEYINNTDFKQLYQI----LTDFDIRFYMYELLKALD 146
           N+++L+D   + ++       LVFEYI +     L +     L    I+  M +LL  +D
Sbjct: 381 NVVRLLDVSHNTITDREIRLNLVFEYIEHDLATYLAKCPSPGLGPDRIKDLMLQLLNGVD 560

Query: 147 YCHSKGIMHRDVKPHNVMIDHQQKKLRLIDWGLAEFYHPAQEYNVRVASRYFKGPELLVD 206
           + HS  I+HRD+KP N++I  +  +L+L D+GLA  Y         V + +++ PE+L+ 
Sbjct: 561 FLHSNRIVHRDLKPQNLLIS-KDGRLKLADFGLARIYSFHMALTTVVVTLWYRSPEVLMQ 737

Query: 207 YQMYDYSLDMWSLGCMLASMIFRKEPFFHGQDNYDQLVRIAKVLGTDELYGYLKKYHIDL 266
            + Y  S+D+WS GC+ A + F +   F G   +DQL +I +V+G      + +   +  
Sbjct: 738 AE-YGTSVDIWSCGCIFAEL-FTRRALFKGSSEFDQLKKIFEVIGLPPAGDWPEGVSV-- 905

Query: 267 DPHFNDILGQHSRKRWENFIHSENRHLVSPEALDLLDKLLRYDHQQRLTAKEAMEHPYF 325
             H N           +  +       + P+A DL++K+L +   +R++++E++ HPY 
Sbjct: 906 --HRNSFRPTPPVP-LQTLVPE-----MDPQAKDLMEKMLVFKSGRRISSRESLLHPYL 1058
>04138
          Length = 800

 Score = 95.9 bits (237), Expect = 2e-20,   Method: Compositional matrix adjust.
 Identities = 62/196 (31%), Positives = 104/196 (53%), Gaps = 7/196 (3%)
 Frame = +1

Query: 145 LDYCHSKGIMHRDVKPHNVMIDHQQKKLRLIDWGLAEFY----HPAQEYNVRVASRYFKG 200
           L Y H   I+HRD+K  N++I  +Q  L+L D+GLA  +         Y  RV + +++ 
Sbjct: 52  LYYIHRNKILHRDMKAANILIT-KQGVLKLADFGLARAFSVNLRQPNRYTNRVVTLWYRP 228

Query: 201 PELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGQDNYDQLVRIAKVLG--TDELYGY 258
           PELL+  + Y  ++D W  GC++A M + + P   G    +QL  I ++ G  T E++  
Sbjct: 229 PELLLGDRNYSTAIDQWGAGCIMAEM-WTRNPIMQGTTEQNQLTLITQLCGSITPEVWPG 405

Query: 259 LKKYHIDLDPHFNDILGQHSRKRWENFIHSE-NRHLVSPEALDLLDKLLRYDHQQRLTAK 317
           + +  +     ++ I G  +  R +N I     R L  P  LDL ++LL+ D  QR++A 
Sbjct: 406 VTQLSM-----YHQIKGALAAGR-KNIIRDRFARILKDPYGLDLFERLLKMDPSQRISAD 567

Query: 318 EAMEHPYFYPVVKEQS 333
           EA+ H +F+  V+ +S
Sbjct: 568 EALNHDFFWVGVEPKS 615
>01707
          Length = 757

 Score = 95.1 bits (235), Expect = 4e-20,   Method: Compositional matrix adjust.
 Identities = 54/162 (33%), Positives = 96/162 (59%), Gaps = 4/162 (2%)
 Frame = +1

Query: 94  NIIKLIDTVKDPVSKTPALVFEYINNTDFKQLYQI---LTDFDIRFYMYELLKALDYCHS 150
           N+++LI+  +    K   LVF+Y+++T   +L +    L +  ++  +Y+ L A+++CH 
Sbjct: 244 NLVRLIEVFRR--KKRLHLVFDYVDHTLLNELDRYPRGLPEPMVKRIIYQTLLAVNFCHQ 417

Query: 151 KGIMHRDVKPHNVMIDHQQKKLRLIDWGLAEFYH-PAQEYNVRVASRYFKGPELLVDYQM 209
              +HRDVKP N++I  +Q +++L D+G A     P  EY   VA+R+++ PELLV    
Sbjct: 418 YNTIHRDVKPENILIT-RQGQVKLCDFGFARILTGPGDEYTDYVATRWYRAPELLVGDTQ 594

Query: 210 YDYSLDMWSLGCMLASMIFRKEPFFHGQDNYDQLVRIAKVLG 251
           Y   +D+W++GC+ A ++   +  + G+ + DQL  I K LG
Sbjct: 595 YGPPVDVWAIGCVFAELL-TGQALWPGRSDVDQLHLIRKTLG 717
>29581
          Length = 1278

 Score = 94.4 bits (233), Expect = 7e-20,   Method: Compositional matrix adjust.
 Identities = 74/255 (29%), Positives = 126/255 (49%), Gaps = 6/255 (2%)
 Frame = -2

Query: 88   NLRGGTNIIKLIDTVKDPVSKTPALVFEYINNTDFKQLYQILTDFD---IRFYMYELLKA 144
            NLR   NI++L + V      +  LV EY        L  +   F    ++  + +LLK 
Sbjct: 1187 NLRH-QNIVQLQEVVVGKSLDSLFLVMEYCEQDLASLLDNMPAPFSESQVKCIVLQLLKG 1011

Query: 145  LDYCHSKGIMHRDVKPHNVMIDHQQKKLRLIDWGLAEFY-HPAQEYNVRVASRYFKGPEL 203
            L Y H   I+HRD+K  N+++   +  +++ D+GLA  Y  P +    +V + +++ PEL
Sbjct: 1010 LRYLHEAFIIHRDLKVSNLLMT-DKGCVKIADFGLARNYGKPQKPMTPKVVTLWYRAPEL 834

Query: 204  LVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGQDNYDQLVRIAKVLGT--DELYGYLKK 261
            L   + +  ++DMWS GC+L  ++  K P   G+ +  Q+  I ++LGT  D ++    +
Sbjct: 833  LFGSKTHSTAIDMWSAGCILGELLGHK-PLMPGRSDLQQIELIMELLGTPNDTIWPGFSQ 657

Query: 262  YHIDLDPHFNDILGQHSRKRWENFIHSENRHLVSPEALDLLDKLLRYDHQQRLTAKEAME 321
                  P F     +  ++ + N  H+     +S   + LL+ L  Y  Q+R TA++ +E
Sbjct: 656  L-----PAFEQFTLK--KQPYNNLRHT--FPWLSESGIRLLNGLFMYHPQKRATAEDCLE 504

Query: 322  HPYFYPVVKEQSQPC 336
            H YF    KEQ  PC
Sbjct: 503  HSYF----KEQPYPC 471
>04591
          Length = 1117

 Score = 93.6 bits (231), Expect = 1e-19,   Method: Compositional matrix adjust.
 Identities = 68/229 (29%), Positives = 108/229 (47%), Gaps = 14/229 (6%)
 Frame = -2

Query: 112 LVFEYINNTDFKQLYQILTDF---DIRFYMYELLKALDYCHSKGIMHRDVKPHNVMIDHQ 168
           L+FEY +      L  +   F   D +  M +LL  L Y H+K I+HRD+K  N+++  +
Sbjct: 966 LIFEYCDYDLAGLLNNLRVKFSLADKKNLMSQLLNGLFYIHTKQILHRDIKAANILLT-R 790

Query: 169 QKKLRLIDWGLAEFYHPAQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIF 228
              L+L D+GL+  +  ++    RV + +++ PELL+  + Y   +DMW +GC++A M  
Sbjct: 789 DGVLKLADFGLSRPWVKSKRLTNRVVTLWYRPPELLLGEREYGPEIDMWGVGCIMAEMWS 610

Query: 229 RKEPFFHGQDNYDQLVRIAKVLGT-----------DELYGYLKKYHIDLDPHFNDILGQH 277
           RK P   G+    QL  I  + G+            ELYG L            D+    
Sbjct: 609 RK-PLMQGRSEQHQLSLITDLCGSLNAEVWPGVTKLELYGKL------------DLPQGK 469

Query: 278 SRKRWENFIHSENRHLVSPEALDLLDKLLRYDHQQRLTAKEAMEHPYFY 326
            RK  E  +      L + E  +L+D  LR D  QR+    A+ H +F+
Sbjct: 468 PRKVKERMLDL----LKNKEGAELIDIFLRLDPGQRMNCDNALSHDFFW 334
>32000
          Length = 644

 Score = 87.0 bits (214), Expect = 1e-17,   Method: Compositional matrix adjust.
 Identities = 49/158 (31%), Positives = 84/158 (53%), Gaps = 3/158 (1%)
 Frame = -1

Query: 171 KLRLIDWGLAEFYH-PAQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFR 229
           K+++ D+GLA  +  P + Y   V + +++ PE+L+  + Y   +D+WSLGC+   M+ R
Sbjct: 575 KMKIADFGLARVFGLPVRTYTHEVITLWYRAPEILLGCRFYSVPVDIWSLGCIFVEMMTR 396

Query: 230 KEPFFHGQDNYDQLVRIAKVLGT--DELYGYLKKYHIDLDPHFNDILGQHSRKRWENFIH 287
           +   F G    DQL RI + LGT  ++++  + K      P +     +   K  E  + 
Sbjct: 395 RA-LFPGDSEIDQLYRIFRTLGTPDEKVWPGVSKL-----PDYKPTFPKWPLKNLETVVS 234

Query: 288 SENRHLVSPEALDLLDKLLRYDHQQRLTAKEAMEHPYF 325
                 +S   LDLL ++L Y+  +R++A+ AM HPYF
Sbjct: 233 ------LSKVGLDLLKRMLTYNPNRRISARSAMRHPYF 138
>01756
          Length = 1858

 Score = 82.0 bits (201), Expect = 4e-16,   Method: Compositional matrix adjust.
 Identities = 68/270 (25%), Positives = 116/270 (42%), Gaps = 18/270 (6%)
 Frame = -3

Query: 1    MPGPAAGSRARVYAEVNSLRSREYWDYEAHVPSWGNQD-DYQLVRKLGRGKYSEVFEAIN 59
            M   A+ SR R   +     S+ Y  YE     + ++D  Y+ + K+G+G + EVF+A  
Sbjct: 1841 MSSTASASREREQKD-----SQRYSPYETLKFPFCDEDAKYEKLAKIGQGTFGEVFKARC 1677

Query: 60   ITNNEXXXXXXXXXXXXXX----XXXXXXXXXNLRGGTNIIKLIDTVKDPVSKTPA---- 111
                +                            L    N++ LI+      +        
Sbjct: 1676 KKTKQVVAMKKVLMDNEKEGFPITALREIKILQLLNHENVVDLIEICSTKATSANRYKSM 1497

Query: 112  --LVFEYINNTDFKQLYQILTDF---DIRFYMYELLKALDYCHSKGIMHRDVKPHNVMID 166
              LVFE+  +     L  +   F   +I+  M +L+  L Y H   I+HRD+K  N++I 
Sbjct: 1496 FYLVFEFCEHDLAGLLSNMSVVFNLPEIKEVMKQLMNGLYYIHRNKILHRDMKAANILIT 1317

Query: 167  HQQKKLRLIDWGLAEFY----HPAQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCM 222
             +Q  L+L D+GLA  +         Y  RV + +++ PELL+  + Y  ++D W  GC+
Sbjct: 1316 -KQGVLKLADFGLARAFSVNLRQPNRYTNRVVTLWYRPPELLLGDRNYSTAIDQWGAGCI 1140

Query: 223  LASMIFRKEPFFHGQDNYDQLVRIAKVLGT 252
            +A M + + P   G    +QL  I ++ G+
Sbjct: 1139 MAEM-WTRNPIMQGTTEQNQLTLITQLCGS 1053
>21079
          Length = 878

 Score = 72.8 bits (177), Expect = 2e-13,   Method: Compositional matrix adjust.
 Identities = 39/133 (29%), Positives = 76/133 (57%), Gaps = 5/133 (3%)
 Frame = +1

Query: 95  IIKLIDTVKDPVSKTPALVFEYINNTD-FKQLYQ---ILTDFDIRFYMYELLKALDYCHS 150
           ++ L D  + P  +T  LV E++   + F+++ +   +LT+ D   ++ ++   + Y H+
Sbjct: 10  LLMLWDAFEAP--RTMVLVMEFVGAGELFERVIRDDFVLTERDCVHFVRQICSGVGYMHT 183

Query: 151 KGIMHRDVKPHNVM-IDHQQKKLRLIDWGLAEFYHPAQEYNVRVASRYFKGPELLVDYQM 209
           + I+H D+KP NV+ +     ++++ID+GLA FY P     V   +  F  PE +V+Y  
Sbjct: 184 QSILHLDLKPENVLCVSDNSNQIKIIDFGLARFYKPGDSLQVLFGTPEFIAPE-VVNYDE 360

Query: 210 YDYSLDMWSLGCM 222
            +++ DMWS+G +
Sbjct: 361 INFTTDMWSIGVI 399
>15910
          Length = 1361

 Score = 72.0 bits (175), Expect = 3e-13,   Method: Compositional matrix adjust.
 Identities = 53/207 (25%), Positives = 94/207 (45%), Gaps = 2/207 (0%)
 Frame = +2

Query: 130 TDFDIRFYMYELLKALDYCHSKGIMHRDVKPHNVMIDHQQ--KKLRLIDWGLAEFYHPAQ 187
           T+ D    + ++L  + Y H+ G++HRD+KP N++ +      KL+L D+GL+    P  
Sbjct: 458 TEKDAARAISDILHGVQYIHANGVVHRDLKPENLLYECMTDDSKLKLADFGLSRIIEPEV 637

Query: 188 EYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGQDNYDQLVRIA 247
           + +    +  +  PE+L   + Y  S+DMWS+G +   ++   EPFF  ++ +       
Sbjct: 638 QMSTVCGTPGYCAPEVLKGDK-YTPSVDMWSVGVIAYILLCGYEPFF-AENEF------- 790

Query: 248 KVLGTDELYGYLKKYHIDLDPHFNDILGQHSRKRWENFIHSENRHLVSPEALDLLDKLLR 307
                 E+Y  + K     D  +           W           +S  A D++ KLL 
Sbjct: 791 ------EMYRKIIKGEYKFDEEY-----------WSE---------ISENAKDVVRKLLV 892

Query: 308 YDHQQRLTAKEAMEHPYFYPVVKEQSQ 334
            D ++RLTA EA+  P+   V  + + 
Sbjct: 893 IDPKKRLTATEALRLPWVKGVATKTTN 973
>23319
          Length = 2235

 Score = 71.2 bits (173), Expect = 6e-13,   Method: Compositional matrix adjust.
 Identities = 45/135 (33%), Positives = 65/135 (48%), Gaps = 3/135 (2%)
 Frame = +3

Query: 208 QMYDYSLDMWSLGCMLASMIFRKEPFFHGQDNYDQLVRIAKVLGT---DELYGYLKKYHI 264
           +MY  S+DMWS GC+ A +     P F G D+ DQL RI K+LGT   D+  G  +  + 
Sbjct: 21  KMYSTSIDMWSAGCIFAELANAGRPLFPGNDDDDQLKRIFKLLGTPTEDQWPGMTQLPNY 200

Query: 265 DLDPHFNDILGQHSRKRWENFIHSENRHLVSPEALDLLDKLLRYDHQQRLTAKEAMEHPY 324
            + P +      H    W+  +   N      +  DLL  LL      R++A EA++HPY
Sbjct: 201 RMFPMY------HVTTTWQQVVPKLNS-----KGRDLLQCLLVCCPSDRMSADEALQHPY 347

Query: 325 FYPVVKEQSQPCAEN 339
           F  +     QP  +N
Sbjct: 348 FADLPPLVRQP*TQN 392
>26560
          Length = 398

 Score = 70.1 bits (170), Expect = 1e-12,   Method: Compositional matrix adjust.
 Identities = 35/108 (32%), Positives = 65/108 (60%)
 Frame = -1

Query: 126 YQILTDFDIRFYMYELLKALDYCHSKGIMHRDVKPHNVMIDHQQKKLRLIDWGLAEFYHP 185
           + + T+ ++RFY  E++  L++ HS+ +++RD+KP N+++D +   +R+ D GLA  +  
Sbjct: 374 HGVFTEKEVRFYAAEVMLGLEHMHSRFVVYRDLKPANILLD-ENGHVRISDLGLACDFSK 198

Query: 186 AQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPF 233
            + +   V +  +  PE+L+  Q YD S D +S GCML  ++    PF
Sbjct: 197 KRPH-ASVGTHGYMAPEVLMKGQSYDSSADWFSFGCMLYKLLKGHSPF 57
>01392
          Length = 1806

 Score = 68.2 bits (165), Expect = 5e-12,   Method: Compositional matrix adjust.
 Identities = 59/224 (26%), Positives = 97/224 (43%), Gaps = 17/224 (7%)
 Frame = -1

Query: 129  LTDFDIRFYMYELLKALDYCHSKGIMHRDVKPHNVMIDHQQK--KLRLIDWGLAEFYH-- 184
            L + +    +  + +ALD+ HSKGI HRD+KP N++ +H      +++ D+ LA      
Sbjct: 1800 LCEREASLVVRHIARALDFLHSKGIAHRDLKPENILCEHLDDVVPVKICDFDLASGISCD 1621

Query: 185  ----PAQEYNVRVASRYFKGPEL----LVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHG 236
                   E    V S  +  PE+    + D   YD   D+WSLG +L  M+    PF+ G
Sbjct: 1620 GDGTKTPELLTPVGSAEYMAPEVVDAWVGDSFSYDKRCDLWSLGIILYIMLCGYPPFY-G 1444

Query: 237  QDNYDQLVRIAKVLGTDELYGYLKKYHIDLDPHFNDILGQHSR---KRWENFIHSENRHL 293
            Q             G D  +   +  H   D  FN I   H +   + W +         
Sbjct: 1443 Q------------CGEDCGWNRGEACHDCQDMLFNSIQDGHYKFPSQEWTS--------- 1327

Query: 294  VSPEALDLLDKLLRYDHQQRLTAKEAMEHPYFY--PVVKEQSQP 335
            +S  A DL+  LL  + ++R +A + ++HP+    P   + + P
Sbjct: 1326 ISSSAKDLIRHLLVREPRKRYSAADVLKHPWICTPPAATQLATP 1195
>00300
          Length = 2318

 Score = 64.7 bits (156), Expect = 6e-11,   Method: Compositional matrix adjust.
 Identities = 52/226 (23%), Positives = 102/226 (45%), Gaps = 18/226 (7%)
 Frame = -1

Query: 40   YQLVRKLGRGKYSEVFEAINITNNEXXXXXXXXXXXXXXXXXXXXXXXNLRGGTNIIKLI 99
            +Q   K+G G++ +V+ A+N++  E                        LR   + IK+ 
Sbjct: 1652 WQRGNKIGEGQFGKVYTAVNMSTGELMALKEMKFQPNDLQ--------QLREMCDEIKIF 1497

Query: 100  DTVKDP---------VSKTPALVF-EYINNTDFKQLYQI-LTDFDIRFYMYELLKALDYC 148
            + ++           V K   L+F EY +    ++  ++ L ++ IR Y  E++ A+++ 
Sbjct: 1496 EGIQHENLVKYYGVEVHKDEMLMFMEYCDTGTIEEAAKMGLPEYLIRRYTREIVLAVNHL 1317

Query: 149  HSKGIMHRDVKPHNVMIDHQQKKLRLIDWGL-----AEFYHPAQEYNVRVASRYFKGPEL 203
            H   I+HRD+K  N+ +      ++L D+G      +    P + +N+ V +  +  PE+
Sbjct: 1316 HENSIVHRDIKGANIFLT-SNGHVKLGDFGCSVKLKSHTTMPGEFHNL-VGTTAYMAPEV 1143

Query: 204  LV--DYQMYDYSLDMWSLGCMLASMIFRKEPFFHGQDNYDQLVRIA 247
                D   Y  + D+WSLGC++  M   K P+    +NY  + ++ 
Sbjct: 1142 FTQNDQGGYGRAADIWSLGCVVIEMATGKRPWHDLDNNYQIMYKVG 1005
>01966
          Length = 1735

 Score = 63.9 bits (154), Expect = 9e-11,   Method: Compositional matrix adjust.
 Identities = 37/137 (27%), Positives = 76/137 (55%), Gaps = 7/137 (5%)
 Frame = -1

Query: 93   TNIIKLIDTVKDPVSKTPALVFEYINNTDFKQLYQ------ILTDFDIRFYMYELLKALD 146
            TNI+ L D + +   +   LVFE+++  D K          +L    ++ Y+++++  ++
Sbjct: 1534 TNIVCLEDVIME--DERLFLVFEFLS-MDLKMYIDKFPEGVVLDRRLVKSYVFQIVTGIN 1364

Query: 147  YCHSKGIMHRDVKPHNVMIDHQQKKLRLIDWGLAE-FYHPAQEYNVRVASRYFKGPELLV 205
            +CH + I+HRD+KP N++I+H    +++ D+G+A  F  P + Y   V + +++ PE+L+
Sbjct: 1363 FCHQRRIVHRDLKPQNLLINH-TGAIKIADFGMARTFALPVRAYTHEVVTLWYRAPEILM 1187

Query: 206  DYQMYDYSLDMWSLGCM 222
              Q    +   W+ G +
Sbjct: 1186 GPQ---STPPXWTCGAL 1145

 Score = 61.6 bits (148), Expect = 4e-10,   Method: Compositional matrix adjust.
 Identities = 39/134 (29%), Positives = 65/134 (48%), Gaps = 3/134 (2%)
 Frame = -3

Query: 210  YDYSLDMWSLGCMLASMIFRKEPFFHGQDNYDQLVRIAKVLGTDELYGYLKKYHIDLDPH 269
            Y   +D+WS+G + A M+ R  P F G    DQL +I +++GT     + + + +   P 
Sbjct: 1175 YSTPVDVWSIGTIFADMLIRT-PIFKGDSEIDQLFKIFRIIGTPTEQTWPEFHKL---PA 1008

Query: 270  FNDILGQHSRKRWENFIHSENRHLVSPEALDLLDKLLRYDHQQRLTAKEAMEHPYFYPV- 328
            FN +        W+    SE    +    LDL+++ L+ D  QR++ K+ ++H YF  V 
Sbjct: 1007 FNGMF-----PLWKEGKLSETLTDLDSLGLDLIERTLKCDPAQRISCKKMLQHAYFLNVD 843

Query: 329  --VKEQSQPCAENT 340
              VK    P  E +
Sbjct: 842  TSVKPVDVPSPEQS 801
>12786
          Length = 460

 Score = 63.5 bits (153), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 41/136 (30%), Positives = 71/136 (52%), Gaps = 22/136 (16%)
 Frame = -3

Query: 134 IRFYMYELLKALDYCHSKGIMHRDVKPHNVMIDHQQKKLRLIDWGLAEFYHPAQEY---N 190
           I+FY  E+L+A+   H++G++H D+KP N M+      L+LID+G+A      +     +
Sbjct: 404 IKFYWREMLRAVKALHNEGVIHSDLKPANFML--VAGNLKLIDFGIANTLQQDKTSVLKD 231

Query: 191 VRVASRYFKGPELLV-------DYQMYD--------YSL----DMWSLGCMLASMIFRKE 231
            RV +  +  PE ++       D  M +        Y +    D+WSLGC+L +M++ + 
Sbjct: 230 SRVGTPSYMSPEAIMAACDDSADDSMEEDGHRTKPKYKVGVRSDVWSLGCILYNMVYGRT 51

Query: 232 PFFHGQDNYDQLVRIA 247
           PF H ++N  +L  I 
Sbjct: 50  PFQHIKNNMGKLQAIT 3
>12721
          Length = 821

 Score = 62.8 bits (151), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 33/95 (34%), Positives = 56/95 (58%), Gaps = 1/95 (1%)
 Frame = +1

Query: 142 LKALDYCHSKGIMHRDVKPHNVMIDHQQKKLRLIDWGL-AEFYHPAQEYNVRVASRYFKG 200
           LKAL + H+ G++HRD+K  ++++ H   K++L D+G  A+     Q+    V + Y+  
Sbjct: 403 LKALAFLHANGVIHRDIKSDSILLSH-DGKVKLXDFGFCAQVTQDLQKRKSLVGTPYWMA 579

Query: 201 PELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFH 235
           PE++     Y   +D+WSLG M+  MI  + PFF+
Sbjct: 580 PEVISRLP-YGPEVDIWSLGIMVMEMIDAEPPFFN 681
>03294
          Length = 1684

 Score = 59.7 bits (143), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 38/132 (28%), Positives = 66/132 (50%), Gaps = 3/132 (2%)
 Frame = -1

Query: 212  YSLDMWSLGCMLASMIFRKEPFFHGQDNYDQLVRIAKVLGTDELYGYLKKYHIDLDPHFN 271
            + +D+WS+G + A M+ R  P F G    DQL +I +++GT     + + + +   P FN
Sbjct: 1678 HPVDVWSIGTIFADMLIRT-PIFKGDSEIDQLFKIFRIIGTPTEQTWPEFHKL---PAFN 1511

Query: 272  DILGQHSRKRWENFIHSENRHLVSPEALDLLDKLLRYDHQQRLTAKEAMEHPYFYPV--- 328
             +        W+    SE    +    LDL+++ L+ D  QR++ K+ ++H YF  V   
Sbjct: 1510 GMF-----PLWKEGKLSETLTDLDSLGLDLIERTLKCDPAQRISCKKMLQHAYFLNVDTS 1346

Query: 329  VKEQSQPCAENT 340
            VK    P  E++
Sbjct: 1345 VKPVDVPSPEHS 1310
>14420
          Length = 528

 Score = 59.3 bits (142), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 30/97 (30%), Positives = 54/97 (55%), Gaps = 1/97 (1%)
 Frame = +2

Query: 140 ELLKALDYCHSKGIMHRDVKPHNVMIDHQQKKLRLIDWGLAEFYHPAQ-EYNVRVASRYF 198
           E L+AL++ H   ++HRD+K  N+++      ++L D+G      P Q + +  V + Y+
Sbjct: 221 ECLQALEFLHENQVIHRDIKSDNILLG-MDGSVKLTDFGFCAQLSPEQSKRSTMVGTPYW 397

Query: 199 KGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFH 235
             PE++   Q Y  ++D+WSLG M   MI  + P+ +
Sbjct: 398 MAPEVVTRKQ-YGPTVDIWSLGVMCIEMIEGEPPYLN 505
>31885
          Length = 529

 Score = 58.5 bits (140), Expect = 4e-09,   Method: Compositional matrix adjust.
 Identities = 30/104 (28%), Positives = 57/104 (54%), Gaps = 4/104 (3%)
 Frame = -2

Query: 134 IRFYMYELLKALDYCHSKGIMHRDVKPHNVMIDHQQKKLRLIDWGLAEFYHPAQEYNVRV 193
           ++FY+ +L   LDY  S+ I+HRD+KP N+++D +Q    + D+ +A      +      
Sbjct: 366 VKFYLCQLALVLDYLRSQKIVHRDIKPDNILLD-EQGHCHVTDFNIATQLEDDELATSTS 190

Query: 194 ASRYFKGPEL----LVDYQMYDYSLDMWSLGCMLASMIFRKEPF 233
            +R +  PE+    + + + Y + +D WSLG  L  ++ ++ PF
Sbjct: 189 GTRPYMAPEVYGVAINERRGYGFPVDWWSLGVSLFELLKKRRPF 58
>30755
          Length = 1137

 Score = 58.5 bits (140), Expect = 4e-09,   Method: Compositional matrix adjust.
 Identities = 34/110 (30%), Positives = 61/110 (55%), Gaps = 1/110 (0%)
 Frame = +2

Query: 127 QILTDFDIRFYMYELLKALDYCHSKGIMHRDVKPHNVMIDHQQKKLRLIDWGLA-EFYHP 185
           +I T+   RFY  E++ AL Y HS+GI++RD+K  N+++D +   +++ D+GL  E    
Sbjct: 17  RIFTEERTRFYGAEIISALGYLHSQGIIYRDLKLENLLLD-KDGHIKVADFGLCKEDITY 193

Query: 186 AQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFH 235
            +       +  +  PE+L D   Y  ++D W  G ++  MI  + PF++
Sbjct: 194 GRTTKTFCGTPEYLAPEVLDDND-YGRAVDWWGTGVVMYEMICGRLPFYN 340
>13212
          Length = 1067

 Score = 57.4 bits (137), Expect = 8e-09,   Method: Compositional matrix adjust.
 Identities = 51/208 (24%), Positives = 87/208 (41%), Gaps = 7/208 (3%)
 Frame = -1

Query: 125  LYQILTDFDIRFYMYELLKALDYCHSKGIMHRDVKPHNVM--IDHQQKKLRLIDWGL-AE 181
            L + +T+  I +  +E+  ALD+ H   ++HRD+K  NV+  ID +   ++L D+G+ A+
Sbjct: 1001 LEKPMTEAQICYVCHEMCMALDFLHRHHVIHRDIKAGNVLLTIDGE---VKLADFGVSAK 831

Query: 182  FYHPAQEYNVRVASRYFKGPELLVDYQM----YDYSLDMWSLGCMLASMIFRKEPFFHGQ 237
                 Q+ +  + + Y+  PE+++   +    YD+  D+WSLG  L     + EP     
Sbjct: 830  NTQTQQKRDTFIGTPYWMAPEVVLCETLKDTPYDFKADIWSLGVTLIEFA-QIEPPNKEM 654

Query: 238  DNYDQLVRIAKVLGTDELYGYLKKYHIDLDPHFNDILGQHSRKRWENFIHSENRHLVSPE 297
                 L++I                      H +D       K+W               
Sbjct: 653  HPMRVLIKI----------------------HKSDPPTLEKPKKWTKLFK---------- 570

Query: 298  ALDLLDKLLRYDHQQRLTAKEAMEHPYF 325
              D + K L  D   R TA E +EHP+ 
Sbjct: 569  --DFIAKCLVKDPNLRPTAAELLEHPFM 492
>19761
          Length = 473

 Score = 57.0 bits (136), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 38/125 (30%), Positives = 65/125 (52%), Gaps = 3/125 (2%)
 Frame = -3

Query: 134 IRFYMYELLKALDYCHSKG--IMHRDVKPHNVMIDHQQKKLRLIDWGLA-EFYHPAQEYN 190
           I  ++ +   AL+Y H+    I+HRD+KP N+ +  ++  +RL D GLA +   PA    
Sbjct: 417 IVCWLMQTASALNYMHTHTPVILHRDLKPQNIYVT-EKGDVRLGDLGLARKLTGPADFAT 241

Query: 191 VRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGQDNYDQLVRIAKVL 250
            +V +  +  PE+L   Q Y+   D+WSLGC+   +  +K     G D    +  + +V+
Sbjct: 240 SQVGTIMYLSPEIL-SQQPYNSKSDIWSLGCVFYDITGKK-----GSDEMGVMFLLVQVM 79

Query: 251 GTDEL 255
           G  +L
Sbjct: 78  GGRKL 64
>18287
          Length = 678

 Score = 57.0 bits (136), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 36/116 (31%), Positives = 63/116 (54%)
 Frame = -3

Query: 210 YDYSLDMWSLGCMLASMIFRKEPFFHGQDNYDQLVRIAKVLGTDELYGYLKKYHIDLDPH 269
           YDYS+D+WS+GC+ A ++ R+   F  Q    QL  I  ++GT       +      +  
Sbjct: 673 YDYSIDIWSVGCIFAELLSRRI-LFQAQGPVQQLDMIINLVGTPRPEDMERA----CEGA 509

Query: 270 FNDILGQHSRKRWENFIHSENRHLVSPEALDLLDKLLRYDHQQRLTAKEAMEHPYF 325
            N IL Q  R++    +++ + H  + EA+ LL ++L  + + R++A+EA+ HPY 
Sbjct: 508 RNHILNQPFRRQNLLTLYNLSPH-ATHEAVRLLTRMLILNPKNRISAEEALSHPYL 344
>18921
          Length = 697

 Score = 56.6 bits (135), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 35/129 (27%), Positives = 63/129 (48%), Gaps = 5/129 (3%)
 Frame = +2

Query: 112 LVFEYINNTDFKQLYQI----LTDFDIRFYMYELLKALDYCHSKGIMHRDVKPHNVMIDH 167
           +V EY        + ++    L + +I   +Y  LK L Y HS+  +HRD+K  N+++++
Sbjct: 245 IVMEYCGAGSVSDIMRLRNKTLVEREIATILYYTLKGLXYLHSRRKIHRDIKAGNILLNN 424

Query: 168 QQKKLRLIDWGLA-EFYHPAQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASM 226
           +    +L D+G+A +      + N  + + Y+  PE++ +   YD   D+WSLG     M
Sbjct: 425 EGHA-KLADFGVAGQLTDTMAKRNTVIGTPYWMAPEVIQEIG-YDCVADIWSLGITALEM 598

Query: 227 IFRKEPFFH 235
              K P   
Sbjct: 599 AEGKPPVME 625
>27405
          Length = 532

 Score = 56.6 bits (135), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 32/114 (28%), Positives = 63/114 (55%), Gaps = 6/114 (5%)
 Frame = -3

Query: 108 KTP---ALVFEYINNTDFK---QLYQILTDFDIRFYMYELLKALDYCHSKGIMHRDVKPH 161
           +TP     + + +N  D       + + T+ ++RFY  E++  L++ HS+ +++RD+KP 
Sbjct: 344 QTPEKLCFILDLMNGGDLHYHLSQHGVFTEKEVRFYAAEVMLGLEHMHSRFVVYRDLKPA 165

Query: 162 NVMIDHQQKKLRLIDWGLAEFYHPAQEYNVRVASRYFKGPELLVDYQMYDYSLD 215
           N+++D +   +R+ D GLA  +   + +   V +  +  PE+L+  Q YD S D
Sbjct: 164 NILLD-ENGHVRISDLGLACDFSKKKPH-ASVGTHGYMAPEVLMKGQAYDSSAD 9
>26711
          Length = 405

 Score = 56.6 bits (135), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 28/95 (29%), Positives = 54/95 (56%), Gaps = 1/95 (1%)
 Frame = -2

Query: 140 ELLKALDYCHSKGIMHRDVKPHNVMIDHQQ-KKLRLIDWGLAEFYHPAQEYNVRVASRYF 198
           ++L  L + H++G++H D+KP N+++   +   ++LID+GLA   +P QE  +   +  F
Sbjct: 392 QVLDILQHVHAQGVVHMDLKPSNLLLSGDKLDSVQLIDFGLARKLYPPQETFLNHGTPGF 213

Query: 199 KGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPF 233
             PE L D +    + D+W +G +   ++  + PF
Sbjct: 212 TSPEAL-DVKPISTASDVWGVGVLAYILLSGQSPF 111
>13592
          Length = 980

 Score = 54.7 bits (130), Expect = 5e-08,   Method: Compositional matrix adjust.
 Identities = 59/299 (19%), Positives = 111/299 (37%), Gaps = 19/299 (6%)
 Frame = +2

Query: 45  KLGRGKYSEVFEAINITNNEXXXXXXXXXXXXXXXXXXXXXXXNLRGGTNIIKLIDTVKD 104
           K+G+G++ +V+ A+N    E                        L+     +K+++ +K 
Sbjct: 5   KIGQGRFGKVYTAVNNNTGELMAMKEIAIQPGETRA--------LKNVAEELKILEGIKH 160

Query: 105 P---------VSKTPALVF-EYINNTDFKQLYQI---LTDFDIRFYMYELLKALDYCHSK 151
                     V +   L+F E  +    + L ++   L +   R +  +LL  +   H  
Sbjct: 161 KNLVRYYGIEVHREELLIFMELCSEGTLESLVELTGGLPEALSRRFTAQLLSGVAELHKH 340

Query: 152 GIMHRDVKPHNVMIDHQQKKLRLIDWGLAEFYHP----AQEYNVRVASRYFKGPELLVDY 207
           GI+HRD+K  N+ +      L+L D+G A           E    V ++ +  PE+    
Sbjct: 341 GIVHRDIKTANIFLVDGSNSLKLGDFGSAVKIQAHTTVPGELQGYVGTQAYMAPEVFTKT 520

Query: 208 QMYDYS--LDMWSLGCMLASMIFRKEPFFHGQDNYDQLVRIAKVLGTDELYGYLKKYHID 265
               +    D+WS+GC++  M   K P+     N+  + ++                 + 
Sbjct: 521 NSDGHGRLADIWSVGCVVVEMASGKRPWAQFDSNFQIMFKVG----------------MG 652

Query: 266 LDPHFNDILGQHSRKRWENFIHSENRHLVSPEALDLLDKLLRYDHQQRLTAKEAMEHPY 324
             P   + L Q                    E  D +D  L++D +QRL+A E +E  +
Sbjct: 653 EKPQAPESLSQ--------------------EGHDFIDHCLQHDPKQRLSAIELLEQNF 769
>28638
          Length = 1458

 Score = 54.7 bits (130), Expect = 6e-08,   Method: Compositional matrix adjust.
 Identities = 25/75 (33%), Positives = 47/75 (62%), Gaps = 1/75 (1%)
 Frame = -1

Query: 153 IMHRDVKPHNVMIDHQQKK-LRLIDWGLAEFYHPAQEYNVRVASRYFKGPELLVDYQMYD 211
           I+H D+KP N+++ + ++  ++++D+G        Q     + SR+++ PE+L+    YD
Sbjct: 768 IIHCDLKPENILLCNPKRSAIKIVDFG--SSCQLGQRIYQYIQSRFYRSPEVLLGVP-YD 598

Query: 212 YSLDMWSLGCMLASM 226
            ++DMWSLGC+L  M
Sbjct: 597 LAIDMWSLGCILVEM 553

 Score = 28.9 bits (63), Expect = 2.9,   Method: Compositional matrix adjust.
 Identities = 29/139 (20%), Positives = 58/139 (41%), Gaps = 30/139 (21%)
 Frame = -2

Query: 217 WSLGCMLASMIFRK----EPFFHGQDNYDQLVRIAKVLGT------DELYGYLKKYHIDL 266
           W L C   ++ + +     P F G + +DQ+++I +VLG       D+     K + +  
Sbjct: 596 WPLTCGXWAVYWWRCTXGNPLFAGSNEFDQMMKIVEVLGVPPRHILDQAQKTRKYFDLLP 417

Query: 267 D-------PHFNDILGQHSRKRWENFIHSE-----NRHLVSP--------EALDLLDKLL 306
           D       P  N      S ++    + +E      R +  P        +  DL+ ++L
Sbjct: 416 DGTYAPKKPRDNKKYKSPSSRKLHEVLGAEKGGPGGRRMGEPGHTVADYLKFKDLILRML 237

Query: 307 RYDHQQRLTAKEAMEHPYF 325
            +D + R++   A++H +F
Sbjct: 236 DFDPKTRISPYYALQHNFF 180
>09606
          Length = 1300

 Score = 54.3 bits (129), Expect = 8e-08,   Method: Compositional matrix adjust.
 Identities = 53/222 (23%), Positives = 90/222 (40%), Gaps = 25/222 (11%)
 Frame = -3

Query: 129 LTDFDIRFYMYELLKALDYCHSKGIMHRDVKPHNVMIDHQQKKLRLIDWGLAE------- 181
           L +  IR +   L+  L Y HS GI+  D++P  V++D     L+  D+GL++       
Sbjct: 842 LPETSIRDFGIHLVTGLHYIHSLGILFHDLRPSKVLLD-TSGVLKFADFGLSKVEGENLE 666

Query: 182 -----FYHPAQEYNVRVASRYFK-----------GPELLVDYQMYDYSL--DMWSLGCML 223
                F     ++N++ A    K            PE+   +Q  + S+  D+W+LGC+ 
Sbjct: 665 ELFFKFAEAGDQWNIQSAEEMMKQVPTSGSPTYMAPEV---FQGAEPSIMSDLWALGCVF 495

Query: 224 ASMIFRKEPFFHGQDNYDQLVRIAKVLGTDELYGYLKKYHIDLDPHFNDILGQHSRKRWE 283
             M     PF    + YD  +   KVL  +     +K   +   P               
Sbjct: 494 YEMFSGHPPFL--GETYD--ITKDKVLNKEFPLPKVKGSRLSAKP--------------- 372

Query: 284 NFIHSENRHLVSPEALDLLDKLLRYDHQQRLTAKEAMEHPYF 325
                      SPE L+LL+ LL+ D  +RL+    ++H ++
Sbjct: 371 -----------SPEFLNLLESLLQKDSTRRLSWASLVKHAFW 279
>03240
          Length = 1683

 Score = 53.9 bits (128), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 42/171 (24%), Positives = 67/171 (39%), Gaps = 48/171 (28%)
 Frame = -3

Query: 112  LVFEYINNTDFKQL---YQILTDFDIRFYMYELLKALDYCHSKGIMHRDVKPHNVMIDHQ 168
             V +Y+   D   L    +IL +   RFY+ EL++A++  H  G +HRD+KP N++ID +
Sbjct: 1060 FVMDYVPGGDLMGLLIRMEILDEPLARFYVAELVQAIESVHRMGFIHRDIKPDNILID-R 884

Query: 169  QKKLRLIDWGL------------------------------------AEFYHPAQEYNVR 192
               ++L D+GL                                     E   P +    R
Sbjct: 883  NGHIKLTDFGLCTGFRWTHNSKYYQRDGTHARQDSMEVKCQLDEQCQCEILKPLERRRKR 704

Query: 193  ---------VASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFF 234
                     V +  +  PE+L     Y    D WS+G +L  M+    PF+
Sbjct: 703  EQRCLAHSLVGTPNYIAPEVLSRLGGYTSVCDWWSVGVILFEMLVGHPPFY 551
>18484
          Length = 635

 Score = 53.5 bits (127), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 34/110 (30%), Positives = 59/110 (53%), Gaps = 6/110 (5%)
 Frame = +1

Query: 136 FYMYELLKALDYCHSKGIMHRDVKPHNVMIDHQQKKLRLIDWGLAEFYHPAQEYNVRVAS 195
           FY  E+   L + H +GI++RD+K  NVM+D  +  +++ D+G+ +     +       +
Sbjct: 55  FYAAEIAVGLFFLHDQGIIYRDLKLDNVMLD-SEGHIKIADFGMCK-----EGMTGDATT 216

Query: 196 RYFKG------PELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGQDN 239
           R F G      PE+++ YQ Y  S+D W+ G +L  M+  + P F G+D 
Sbjct: 217 RTFCGTPDYIAPEIVL-YQPYSKSVDWWAYGVLLFEMLAGQPP-FDGEDE 360
>19094
          Length = 898

 Score = 52.8 bits (125), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 30/101 (29%), Positives = 55/101 (54%), Gaps = 1/101 (0%)
 Frame = +1

Query: 127 QILTDFDIRFYMYELLKALDYCHSKGIMHRDVKPHNVMIDHQQKKLRLIDWGLA-EFYHP 185
           + L + +I   +Y  LK L Y HS+  +HRD+K  N++++++    +L D+G+A +    
Sbjct: 43  KTLVEREIATILYYTLKGL*YLHSRRKIHRDIKAGNILLNNEGHA-KLADFGVAGQLTDT 219

Query: 186 AQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASM 226
             + N  + + Y+  PE++ +   YD   D+WSLG     M
Sbjct: 220 MAKRNTVIGTPYWMAPEVIQEIG-YDCVADIWSLGITALEM 339
>21433
          Length = 590

 Score = 52.0 bits (123), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 28/97 (28%), Positives = 56/97 (57%)
 Frame = +2

Query: 137 YMYELLKALDYCHSKGIMHRDVKPHNVMIDHQQKKLRLIDWGLAEFYHPAQEYNVRVASR 196
           Y+Y+L  AL+YCH + ++HRD+KP N+++   +  L++ D+G +  + P+        + 
Sbjct: 182 YIYQLSSALEYCHYRKVIHRDIKPENLLLG-LKGDLKIADFGWS-VHAPSSRRTTMCGTL 355

Query: 197 YFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPF 233
            +  PE +V+ + +D ++D+WSLG +    +    P 
Sbjct: 356 DYLPPE-MVEGKTHDENVDLWSLGVLCYEFLVGTPPL 463
>18401
          Length = 463

 Score = 50.4 bits (119), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 36/146 (24%), Positives = 74/146 (50%), Gaps = 11/146 (7%)
 Frame = -3

Query: 193 VASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGQDNYDQLVRIAKVLGT 252
           V++R+++ PE++++   + +  D+WS+GC++   ++     F   DN + L  + ++LG+
Sbjct: 449 VSTRHYRAPEVILELG-WSHPCDVWSVGCIMFE-LYTGYTLFQTHDNKEHLAMMERILGS 276

Query: 253 DELYGYLKK-------YHIDLDPHFNDILGQHSRKRWENFIH----SENRHLVSPEALDL 301
              Y   KK       +H  LD      + ++ R+  +  +      EN+     +  DL
Sbjct: 275 LP-YRMAKKTKKQKYFHHGRLDVPERSSMARYVRENTKPLLRYVKDRENKD--HQQLFDL 105

Query: 302 LDKLLRYDHQQRLTAKEAMEHPYFYP 327
           + KLL Y+   R +  +A++HP+F P
Sbjct: 104 MKKLLAYEASSRYSLLQALQHPFFSP 27
>07940
          Length = 1336

 Score = 45.8 bits (107), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 29/105 (27%), Positives = 58/105 (55%), Gaps = 4/105 (3%)
 Frame = -3

Query: 123 KQLYQILTDFDIRFYMYELLKALDYCHSKGIMHRDVKPHNVMIDHQQKKLRLIDWGLA-- 180
           + + ++LT  D+  Y Y++ + ++Y  SK  +HRD+   NV++  ++  L++ D+GL   
Sbjct: 374 QDMLKMLTPKDLISYAYQVARGMEYLASKQCIHRDLAARNVLV-AEEYVLKIADFGLTRN 198

Query: 181 --EFYHPAQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCML 223
             +F +  +  + R+  ++   PE L D + Y    D+WS G +L
Sbjct: 197 LQQFDYYRKTTDGRLPVKWM-APEALFDRK-YTSKSDVWSYGVLL 69
>13078
          Length = 773

 Score = 45.1 bits (105), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 34/125 (27%), Positives = 58/125 (46%), Gaps = 13/125 (10%)
 Frame = -1

Query: 214 LDMWSLGCMLASMIFRKEPFFHGQDNYDQLVRIAKVLGTDELYGYLKK-------YHIDL 266
            D+WS+GC++   ++     F   DN + L  + ++LG+   Y   KK       YH  L
Sbjct: 734 CDVWSIGCIMFE-LYTGYTLFQTHDNKEHLAMMERILGSLP-YRMAKKTKKQKYFYHGRL 561

Query: 267 DPHFNDILGQHSRKRWENFIHSENRHLVSP------EALDLLDKLLRYDHQQRLTAKEAM 320
           D       G++ R      +    R++  P      +  DL+DK+L Y+   R + ++AM
Sbjct: 560 DWDEKSSAGRYVRDN----VKPLRRYVKDPDNEDHQQLFDLMDKMLSYEVSTRYSLRQAM 393

Query: 321 EHPYF 325
            HP+F
Sbjct: 392 RHPFF 378
>37602
          Length = 804

 Score = 45.1 bits (105), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 26/90 (28%), Positives = 43/90 (47%), Gaps = 3/90 (3%)
 Frame = -1

Query: 112 LVFEYINNTDFKQLYQI---LTDFDIRFYMYELLKALDYCHSKGIMHRDVKPHNVMIDHQ 168
           +  EY      + +Y +   LT+  I F   E LK L Y H +G MHRD+K  N+++  +
Sbjct: 288 IAMEYCGGGSMQDIYHVTGPLTEPQIAFVCRETLKGLHYLHRRGKMHRDIKGANILLTEE 109

Query: 169 QKKLRLIDWGLAEFYHPAQEYNVRVASRYF 198
                  D  LA+F+  +  ++  V  + F
Sbjct: 108 G------DVKLADFWRVSSNHSHNVQKKVF 37
>31489
          Length = 329

 Score = 43.9 bits (102), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 26/77 (33%), Positives = 47/77 (61%), Gaps = 6/77 (7%)
 Frame = +3

Query: 94  NIIKLIDTVKDPVS----KTPALVFEYINNTDFKQLY--QILTDFDIRFYMYELLKALDY 147
           NII + + +K   S    K   +VF+ + +   + +Y  Q LT+  IR+++Y++L+ L Y
Sbjct: 33  NIISIREILKPKDSYHDFKDIHVVFDLMESDLHRIIYSDQPLTEEHIRYFLYQILRGLKY 212

Query: 148 CHSKGIMHRDVKPHNVM 164
            HS  ++HRD+KP N++
Sbjct: 213 IHSANVVHRDLKPSNLL 263
>13066
          Length = 551

 Score = 42.7 bits (99), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 25/89 (28%), Positives = 41/89 (46%), Gaps = 3/89 (3%)
 Frame = +3

Query: 135 RFYMYELLKALDYCHSKGIMHRDVKPHNVMI-DHQQKKLRLIDWGLAEFYHPAQEYNVR- 192
           + + Y++  AL+Y HS  + HRD+K  N+++  H   KL    +  A      ++Y  R 
Sbjct: 285 KIWFYQMTTALNYLHSYDVAHRDLKCENILLSSHFNVKLADFGFACACITESGEKYMSRT 464

Query: 193 -VASRYFKGPELLVDYQMYDYSLDMWSLG 220
              S  +  PE++          D WSLG
Sbjct: 465 YCGSAAYAAPEIVYGAPYAPKVADAWSLG 551
>11185
          Length = 473

 Score = 42.4 bits (98), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 31/120 (25%), Positives = 53/120 (44%), Gaps = 25/120 (20%)
 Frame = +1

Query: 133 DIRFYMYELLKALDYCHSKGIMHRDVKPHNVMIDHQQKKLRLIDWGLAE----------- 181
            IR +   L+  L Y HS GI+  D++P  V++D     L+  D+GL++           
Sbjct: 4   SIRDFGIHLVTGLHYIHSLGILFHDLRPSKVLLD-TSGVLKFADFGLSKVEGENLEELFF 180

Query: 182 -FYHPAQEYNVRVASRYFK-----------GPELLVDYQMYDYSL--DMWSLGCMLASMI 227
            F     ++N++ A    K            PE+   +Q  + S+  D+W+LGC+   M 
Sbjct: 181 KFAEAGDQWNIQSAEEMMKQVPTSGSPTYMAPEV---FQGAEPSIMSDLWALGCVFYEMF 351
>01718
          Length = 959

 Score = 42.4 bits (98), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 49/208 (23%), Positives = 89/208 (42%), Gaps = 9/208 (4%)
 Frame = +3

Query: 31  VPSWGNQDDYQLVRKLGRGKYSEVFEAINITNNEXXXXXXXXXXXXXXXXXXXXXXXNLR 90
           V +    DD+ +  K+G G +SEVF+  +    +                       N  
Sbjct: 129 VSALTRLDDF-ICEKIGAGFFSEVFKVTHRITGQVMALKMNTMTSNRHNMLREVQLLNRL 305

Query: 91  GGTNIIKLIDTVKDPVSKTPALVFEYINNTDFKQLYQILTD---FDIRFYM-YELLKALD 146
              NI++ +        +  AL  EYI + + +QL +   +   +  R  +   L + LD
Sbjct: 306 QHANILRFMGVCVHE-GQLHALT-EYIPSGNLEQLLEKKDEELPWTQRIQLTLGLARGLD 479

Query: 147 YCHSKGIMHRDVKPHNVMI---DHQQKKLRLIDWGLA-EFYHPAQEYNV-RVASRYFKGP 201
           Y HS   +HRD+   N++I   D+      + D+GLA +   P  +  +  V S Y+  P
Sbjct: 480 YLHSTRFIHRDLTSKNILIRREDNHGYHAVIADFGLATKIPDPLDKEKLPTVGSPYWMAP 659

Query: 202 ELLVDYQMYDYSLDMWSLGCMLASMIFR 229
           E+L +   Y+   D++S+G ++  +  R
Sbjct: 660 EVL-NGHFYNERADLFSVGIIMCEITAR 740
>05084
          Length = 1324

 Score = 42.4 bits (98), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 27/91 (29%), Positives = 41/91 (45%), Gaps = 1/91 (1%)
 Frame = +2

Query: 236 GQDNYDQLVRIAKVLGTDELYGYLKKYHIDLDPHFNDI-LGQHSRKRWENFIHSENRHLV 294
           G    DQLV I KVLGT       ++   +++P++++    Q     W        R   
Sbjct: 8   GDSGVDQLVEIIKVLGTPT-----REQIREMNPNYSEFKFPQIKAHPWTKVF----RPRT 160

Query: 295 SPEALDLLDKLLRYDHQQRLTAKEAMEHPYF 325
            PEA+ L+ +LL Y    R+   EA  H +F
Sbjct: 161 PPEAIQLVSRLLEYTPSARIQPMEACAHAFF 253
>26009
          Length = 886

 Score = 42.0 bits (97), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 16/33 (48%), Positives = 25/33 (75%)
 Frame = +3

Query: 133 DIRFYMYELLKALDYCHSKGIMHRDVKPHNVMI 165
           + +  M +L+ ALD+ HSK ++HRD+KP NV+I
Sbjct: 714 EAKSVMKQLVSALDFMHSKQLVHRDIKPENVLI 812
>17975
          Length = 449

 Score = 41.6 bits (96), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 17/55 (30%), Positives = 33/55 (60%)
 Frame = +3

Query: 137 YMYELLKALDYCHSKGIMHRDVKPHNVMIDHQQKKLRLIDWGLAEFYHPAQEYNV 191
           Y  ++++A+ YCH   ++HRD+KP NV+   +   ++L D+G +     A+  N+
Sbjct: 282 YFRQIVEAISYCHKLHVVHRDLKPENVVFFEKPGLVKLTDFGFSTCLLQAKA*NI 446
>00715
          Length = 1788

 Score = 40.8 bits (94), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 37/149 (24%), Positives = 61/149 (40%), Gaps = 27/149 (18%)
 Frame = +1

Query: 112 LVFEYINNTDFKQL---YQILTDFDIRFYM-YELLKALDYCHSKGIMHRDVKPHNVMIDH 167
           L  EY+   + + +   +Q   D  +R  +  ++ + L Y HS  I+H D+KP N ++  
Sbjct: 166 LAMEYVGPLNLQTILNDHQQDIDSSMRLSLALQMARGLHYLHSINIVHLDLKPANCLLT- 342

Query: 168 QQKKLRLIDWGLAEFYHP-----------------------AQEYNVRVASRYFKGPELL 204
           +  KLR+ D+G      P                           N    +  ++ PELL
Sbjct: 343 RDLKLRIADFGCCHQLTPTGLDMGEREGGMAGNELELTPVQGAWKNELAGTLAYRAPELL 522

Query: 205 VDYQMYDYSLDMWSLGCMLASMIFRKEPF 233
              Q    S D++SLG  L  M  R+ P+
Sbjct: 523 KGLQPSVRS-DVYSLGITLWQMCTRQGPY 606
>00392
          Length = 668

 Score = 40.4 bits (93), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 25/93 (26%), Positives = 53/93 (56%), Gaps = 3/93 (3%)
 Frame = +3

Query: 134 IRFYMYELLKALDYCHSKG--IMHRDVKPHNVMIDHQQKKLRLIDWGLAEFYHPAQEYNV 191
           ++ +  ++LK L + H++   ++HRD+K  N+ I      +++ D GLA   + +   +V
Sbjct: 252 LKNWCRQVLKGLYFLHTRTPPVIHRDLKCDNIFITGPTGSVKIGDLGLATLKNQSFAKSV 431

Query: 192 RVASRYFKGPELLVDYQMYDYSLDMWSLG-CML 223
            + +  F  PE+  ++  YD ++D+++ G CML
Sbjct: 432 -IGTPEFMAPEMYEEH--YDEAVDVYAFGMCML 521
>12453
          Length = 680

 Score = 37.4 bits (85), Expect = 0.009,   Method: Compositional matrix adjust.
 Identities = 32/116 (27%), Positives = 52/116 (44%), Gaps = 9/116 (7%)
 Frame = +3

Query: 219 LGCMLASMIFRKEPFFHGQDNYDQLVRIAKVLGT---DELYGYLKKYHIDLDPHFNDILG 275
           +GC+   M   + P F G    D+L  I K LGT   D L        I  +P F  +  
Sbjct: 6   VGCIFYEMACGR-PLFPGSTVEDELHLIFKTLGTPTEDSLP------SISRNPDFLAL-- 158

Query: 276 QHSRKRWENFIHSENRHLVS------PEALDLLDKLLRYDHQQRLTAKEAMEHPYF 325
                   N  H +   L++       + LDLL K L+Y+ + R++A ++++H +F
Sbjct: 159 --------NLPHYQGEALITIAPRLDSDGLDLLAKFLKYNAKIRVSAADSLKHSFF 302
>14116
          Length = 1017

 Score = 37.4 bits (85), Expect = 0.009,   Method: Compositional matrix adjust.
 Identities = 24/102 (23%), Positives = 50/102 (49%), Gaps = 5/102 (4%)
 Frame = -1

Query: 133 DIRFYMYELLKALDYCHSKGIMHRDVKPHNVMIDHQQKKLRLIDWGLA-----EFYHPAQ 187
           D+  Y  ++ + +DY      +HRD+   N M+D +   +++ D+GLA     + Y+ ++
Sbjct: 318 DLIMYGVDIARGMDYLAGLKFVHRDLAARNCMLD-EDFHVKVADFGLARDIYEKEYYSSE 142

Query: 188 EYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFR 229
               ++  ++     L  +   YD   D+WS G +L  ++ R
Sbjct: 141 NKKAKLPVKWMALESL--EKGNYDSKTDVWSYGVVLWELLTR 22
>27546
          Length = 426

 Score = 37.4 bits (85), Expect = 0.009,   Method: Compositional matrix adjust.
 Identities = 16/58 (27%), Positives = 35/58 (60%)
 Frame = -1

Query: 135 RFYMYELLKALDYCHSKGIMHRDVKPHNVMIDHQQKKLRLIDWGLAEFYHPAQEYNVR 192
           + + +++ KAL Y HS  I HRD+K  N+++  ++  +++ D+G A +   A   +++
Sbjct: 171 KVWFFQMAKALQYLHSHDIAHRDLKCENILLS-KRLNVKIADFGFARYCRDAAGMDLK 1
>32359
          Length = 928

 Score = 28.5 bits (62), Expect(2) = 0.010,   Method: Compositional matrix adjust.
 Identities = 15/49 (30%), Positives = 26/49 (53%), Gaps = 6/49 (12%)
 Frame = -1

Query: 112 LVFEYINNTDFK------QLYQILTDFDIRFYMYELLKALDYCHSKGIM 154
           LV EY+  T ++      +  Q +    I+ YMY+L ++L Y HS+  +
Sbjct: 202 LVLEYVPETVYRVARHYSKSKQTIPILYIKLYMYQLFRSLAYIHSQACV 56

 Score = 27.3 bits (59), Expect(2) = 0.010,   Method: Compositional matrix adjust.
 Identities = 9/21 (42%), Positives = 15/21 (71%)
 Frame = -3

Query: 152 GIMHRDVKPHNVMIDHQQKKL 172
           G+ HRD+KP N+++D +   L
Sbjct: 65  GVCHRDIKPQNLLLDPETGVL 3
>06358
          Length = 1517

 Score = 37.0 bits (84), Expect = 0.013,   Method: Compositional matrix adjust.
 Identities = 34/127 (26%), Positives = 58/127 (45%), Gaps = 20/127 (15%)
 Frame = +3

Query: 129 LTDFDIRFYMYELLKALDYCHSKG-IMHRDVKPHNVMIDHQQKKLRLIDWGLA--EFY-- 183
           L D +I+  + ++ +AL + H+   +MHR+V P  +M+       +L  W LA  EF   
Sbjct: 351 LYDVEIKHGLLQVTEALGFLHNDAKMMHRNVCPEAIMLT------KLGSWKLAGYEFCVR 512

Query: 184 ----------HPAQEYNVRVASRY-----FKGPELLVDYQMYDYSLDMWSLGCMLASMIF 228
                     +P  E+   +A        F  PE ++  Q    S DM+SLG ++ S+  
Sbjct: 513 SSDPQSTDPSYPFYEWRSDIAPVTQPHLDFMAPEYVLTMQCGTGS-DMFSLGLLVYSVFA 689

Query: 229 RKEPFFH 235
           + +P F 
Sbjct: 690 KGKPLFE 710
>01106
          Length = 878

 Score = 36.2 bits (82), Expect = 0.019,   Method: Compositional matrix adjust.
 Identities = 19/60 (31%), Positives = 35/60 (58%), Gaps = 5/60 (8%)
 Frame = +3

Query: 111 ALVFEYINNTDFKQL----YQILTDFDIRFYMYELLKALDYCHSKG-IMHRDVKPHNVMI 165
           A+VFE +     K +    YQ +   +++  + ++L+ L Y H+K  I+H D+KP N++I
Sbjct: 570 AMVFEVLGYNLLKLIIRSNYQGIPIHNVKLIIRQVLEGLSYMHAKCRIIHTDIKPENILI 749
>18481
          Length = 437

 Score = 36.2 bits (82), Expect = 0.019,   Method: Compositional matrix adjust.
 Identities = 18/50 (36%), Positives = 30/50 (60%), Gaps = 2/50 (4%)
 Frame = -1

Query: 140 ELLKALDYCHSKGIMHRDVKPHNVM--IDHQQKKLRLIDWGLAEFYHPAQ 187
           +LL  L++ H K  +HRD+KP N +  +     +L +ID+GL++ Y   Q
Sbjct: 173 QLLSRLEFIHQKCFIHRDLKPDNFLMGLGRHCHRLYIIDFGLSKRYKDTQ 24
>21800
          Length = 855

 Score = 35.4 bits (80), Expect = 0.031,   Method: Compositional matrix adjust.
 Identities = 18/60 (30%), Positives = 35/60 (58%), Gaps = 5/60 (8%)
 Frame = +2

Query: 111 ALVFEYINNTDFKQL----YQILTDFDIRFYMYELLKALDYCHSK-GIMHRDVKPHNVMI 165
            +VFE +     K +    YQ +   +++  + ++L+ L+Y H+K  I+H D+KP N++I
Sbjct: 557 CMVFEVLGYNLLKLIIRSNYQGIPVHNVKLIIRQVLEGLNYLHAKCNIIHTDIKPENILI 736
>28157
          Length = 400

 Score = 35.4 bits (80), Expect = 0.035,   Method: Compositional matrix adjust.
 Identities = 29/104 (27%), Positives = 47/104 (45%), Gaps = 13/104 (12%)
 Frame = +3

Query: 94  NIIKLIDTVKD-PVSKTPALVFEYINNTDFKQLYQIL---------TDFDIRFYMYELLK 143
           NI+ L    +D PV     LV EY    +   LY +L         T      ++ +   
Sbjct: 93  NIVCLYGACRDHPV----CLVMEY---AEGGSLYNVLHGSGPQPQYTAAHAMNWLLQCAL 251

Query: 144 ALDYCHS---KGIMHRDVKPHNVMIDHQQKKLRLIDWGLAEFYH 184
            ++Y H    K ++HRD+KP N+++     KL++ D+G A   H
Sbjct: 252 GVEYLHGMKPKALIHRDLKPPNLLLIQCGTKLKICDFGTACDIH 383
>02638
          Length = 1490

 Score = 34.7 bits (78), Expect = 0.052,   Method: Compositional matrix adjust.
 Identities = 32/128 (25%), Positives = 52/128 (40%)
 Frame = +1

Query: 198 FKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGQDNYDQLVRIAKVLGTDELYG 257
           F  PE+L   + Y  + D+WS+GC++  M   + P ++  D  + L  I K+  +     
Sbjct: 34  FMAPEVL-RGESYGRACDVWSVGCVMIEMCTCRPP-WNSHDISNHLALIFKIASS----- 192

Query: 258 YLKKYHIDLDPHFNDILGQHSRKRWENFIHSENRHLVSPEALDLLDKLLRYDHQQRLTAK 317
                 +D  P                    EN   +SP   DL+ + L  D   R +AK
Sbjct: 193 ------VDPPP------------------IPEN---MSPPVRDLMLRCLEQDSDFRPSAK 291

Query: 318 EAMEHPYF 325
           + + HP F
Sbjct: 292 DLLMHPLF 315
>20773
          Length = 391

 Score = 33.5 bits (75), Expect = 0.13,   Method: Compositional matrix adjust.
 Identities = 18/50 (36%), Positives = 27/50 (54%)
 Frame = -1

Query: 275 GQHSRKRWENFIHSENRHLVSPEALDLLDKLLRYDHQQRLTAKEAMEHPY 324
           G H R+    F H+    +V+    +L+ +LL YD  QRLT   A+ HP+
Sbjct: 370 GLHRRRSRPVFPHTT---VVTQHFYNLVQRLLTYDPSQRLTPDLALSHPF 230
>15931
          Length = 447

 Score = 33.1 bits (74), Expect = 0.19,   Method: Compositional matrix adjust.
 Identities = 12/29 (41%), Positives = 20/29 (68%)
 Frame = +1

Query: 297 EALDLLDKLLRYDHQQRLTAKEAMEHPYF 325
           +  DL+DK+L Y+   R + ++AM HP+F
Sbjct: 70  QLFDLMDKMLSYEVSTRYSLRQAMRHPFF 156
>35032
          Length = 465

 Score = 32.7 bits (73), Expect = 0.24,   Method: Compositional matrix adjust.
 Identities = 13/27 (48%), Positives = 18/27 (66%)
 Frame = +3

Query: 300 DLLDKLLRYDHQQRLTAKEAMEHPYFY 326
           DL+ +LL YD  +RLT   A+ HP+ Y
Sbjct: 147 DLVKRLLNYDPSKRLTPXXALAHPFLY 227
>19301
          Length = 712

 Score = 32.7 bits (73), Expect = 0.24,   Method: Compositional matrix adjust.
 Identities = 19/76 (25%), Positives = 40/76 (52%), Gaps = 6/76 (7%)
 Frame = +2

Query: 111 ALVFEYINNTDFKQLYQILTDFD------IRFYMYELLKALDYCHSKGIMHRDVKPHNVM 164
            ++ EY     + QLY++L D        +  +  ++   ++Y HS  I+HRD+K  NV+
Sbjct: 497 CIIMEY---CPYGQLYEVLRDGKEIPPALVLDWSKQIASGMNYLHSHKIIHRDLKSPNVL 667

Query: 165 IDHQQKKLRLIDWGLA 180
           +  +   +++ D+G +
Sbjct: 668 V-AKNDVVKISDFGTS 712
>26909
          Length = 394

 Score = 32.3 bits (72), Expect = 0.27,   Method: Compositional matrix adjust.
 Identities = 31/112 (27%), Positives = 49/112 (43%), Gaps = 13/112 (11%)
 Frame = +2

Query: 227 IFRKEPFFHGQD---------NYDQLVRIAKVLGTDELYGYLKKYHIDLDPHFNDILGQH 277
           +   EP FH +          ++DQL RI  V+G  +   +     I   P    +    
Sbjct: 14  LLTSEPIFHCRQEDIKTSNPYHHDQLDRIFNVMGFPQEKDW---EDIRRMPEHQQLTKDF 184

Query: 278 SRKRWEN--FIHSENRHLVSPE--ALDLLDKLLRYDHQQRLTAKEAMEHPYF 325
            R  + N   +    +H V  +  A  LL KLL  D  +R+T+++AM+ PYF
Sbjct: 185 KRSSYVNCNLMKYMEKHKVKADSKAFHLLQKLLTMDPVKRITSEQAMKDPYF 340
>29590
          Length = 320

 Score = 30.4 bits (67), Expect = 0.98,   Method: Composition-based stats.
 Identities = 17/58 (29%), Positives = 27/58 (46%)
 Frame = +3

Query: 176 DWGLAEFYHPAQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPF 233
           D G A   +  ++    + +  +  PE+L DY+      DMWSLG +   M+    PF
Sbjct: 6   DLGFACLTNTGEDIRDIIGTPDYVAPEVL-DYEPLSIQTDMWSLGVLSYVMLTACSPF 176
>14104
          Length = 573

 Score = 30.4 bits (67), Expect = 1.0,   Method: Compositional matrix adjust.
 Identities = 10/32 (31%), Positives = 19/32 (59%)
 Frame = +1

Query: 294 VSPEALDLLDKLLRYDHQQRLTAKEAMEHPYF 325
            +P+A+  +   L+ D  +RLT  + ++HPY 
Sbjct: 88  AAPQAMSFMQSCLKMDPAERLTCHQLLQHPYM 183
>37063
          Length = 455

 Score = 30.4 bits (67), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 24/79 (30%), Positives = 37/79 (46%), Gaps = 13/79 (16%)
 Frame = -2

Query: 158 VKPHNVMIDHQQK--KLRLIDWGLAEFYHP------AQEYNVRVASRYFKGPELLVDYQM 209
           +KP N++ +H  +   L++ D+ LA   +         E    V S  +  PE+ VD  +
Sbjct: 454 LKPENILCEHLDEVVPLKICDFDLASGINCDGDGTKTPELLTPVGSAEYMAPEV-VDAWV 278

Query: 210 -----YDYSLDMWSLGCML 223
                YD   DMWSLG +L
Sbjct: 277 GESFSYDKRCDMWSLGIIL 221
>17644
          Length = 463

 Score = 29.3 bits (64), Expect = 2.8,   Method: Compositional matrix adjust.
 Identities = 12/24 (50%), Positives = 16/24 (66%)
 Frame = +3

Query: 301 LLDKLLRYDHQQRLTAKEAMEHPY 324
           L+ +LL YD  QRLT   A+ HP+
Sbjct: 90  LVQRLLTYDPSQRLTPDLALSHPF 161
>36481
          Length = 806

 Score = 28.9 bits (63), Expect = 3.1,   Method: Compositional matrix adjust.
 Identities = 12/36 (33%), Positives = 22/36 (61%), Gaps = 1/36 (2%)
 Frame = +2

Query: 134 IRFYMYELLKALDYCHSKGIMHRDVKPHNVM-IDHQ 168
           +R   Y+L  A+++ H   + H D+KP N++ +D Q
Sbjct: 677 VRHISYQLCYAVNFLHENQLTHTDLKPENILFVDSQ 784
>18663
          Length = 600

 Score = 28.9 bits (63), Expect = 3.1,   Method: Compositional matrix adjust.
 Identities = 13/34 (38%), Positives = 21/34 (61%)
 Frame = +2

Query: 200 GPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPF 233
            PE+L   + Y +S+D W+LG +L  M+  + PF
Sbjct: 32  APEILRG-EDYGFSVDWWALGVLLYEMLAGRSPF 130
>29360
          Length = 363

 Score = 28.9 bits (63), Expect = 3.6,   Method: Compositional matrix adjust.
 Identities = 21/59 (35%), Positives = 31/59 (52%), Gaps = 4/59 (6%)
 Frame = +3

Query: 111 ALVFEYI--NNTDF--KQLYQILTDFDIRFYMYELLKALDYCHSKGIMHRDVKPHNVMI 165
            LVFE +  N  DF  +  +Q L    IR    ++L AL      G++H D+KP N+M+
Sbjct: 183 CLVFEMLEQNLYDFLKQNKFQPLPLKYIRPITQQVLTALRKLKQLGLIHADLKPENIML 359
>37603
          Length = 1005

 Score = 28.1 bits (61), Expect = 6.3,   Method: Compositional matrix adjust.
 Identities = 10/25 (40%), Positives = 15/25 (60%)
 Frame = +2

Query: 139 YELLKALDYCHSKGIMHRDVKPHNV 163
           Y +   L +CH +GI  RD +PH +
Sbjct: 551 YHVRIQLSFCHVEGIKRRDGRPHAI 625
>20152
          Length = 445

 Score = 27.7 bits (60), Expect = 7.0,   Method: Compositional matrix adjust.
 Identities = 12/39 (30%), Positives = 22/39 (56%)
 Frame = +1

Query: 201 PELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGQDN 239
           PE+L+       ++D+WSLG +L  ++  + PF    D+
Sbjct: 1   PEILLGDSYDAPAVDVWSLGVILYMLVVGEAPFQEANDS 117
>12045
          Length = 1137

 Score = 27.7 bits (60), Expect = 7.0,   Method: Compositional matrix adjust.
 Identities = 17/47 (36%), Positives = 28/47 (59%), Gaps = 1/47 (2%)
 Frame = -2

Query: 243 LVRIAKVLGTDELYGYLKKYHIDLDP-HFNDILGQHSRKRWENFIHS 288
           ++++A+V  T  +Y Y K  H  L   +   ILG  ++KR E+F+HS
Sbjct: 302 VIKLARVKNTC-IY*YTKMIHFFLAVFYLPQILGSRTKKRREDFLHS 165
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|88196800|ref|NP_001034635.1| myosin VI [Mus musculus]
         (1262 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

01284                                                                 370   e-102
25922                                                                 113   5e-25
14047                                                                 110   3e-24
30605                                                                  97   3e-20
05656                                                                  32   1.1  
07324                                                                  32   1.5  
>01284
          Length = 1603

 Score =  370 bits (951), Expect = e-102,   Method: Compositional matrix adjust.
 Identities = 168/267 (62%), Positives = 220/267 (82%)
 Frame = +2

Query: 637 KLSFISVGNKFKTQLNLLLDKLRSTGASFIRCIKPNLKMTSHHFEGAQILSQLQCSGMVS 696
           KL+FISVG KF+ QL +L+DKL+STG +FIRCIKPN+KM  H FEGA ILSQLQC+GMVS
Sbjct: 2   KLNFISVGTKFRKQLLVLMDKLKSTGTNFIRCIKPNVKMVDHLFEGANILSQLQCAGMVS 181

Query: 697 VLDLMQGGFPSRASFHELYNMYKKYMPEKLARLDPRLFCKALFKALGLNEVDYKFGLTKV 756
           VL+LMQ GFPSR  F ELYNMYKKY+P +L+RLDPRLFCK+LFKALGL++ D+KFGLTKV
Sbjct: 182 VLELMQQGFPSRTPFSELYNMYKKYLPPELSRLDPRLFCKSLFKALGLDDKDFKFGLTKV 361

Query: 757 FFRPGKFAEFDQIMKSDPDHLAELVKRVNLWLVCSRWKKVQWCSLSVIKLKNKIKYRAEA 816
           FFRPGKFAEFDQIMKSDP++LAELVK+V  WL+CSRWKK QWC+LSVIKLKNKI+YRAE 
Sbjct: 362 FFRPGKFAEFDQIMKSDPENLAELVKKVKKWLLCSRWKKAQWCTLSVIKLKNKIRYRAEQ 541

Query: 817 CIKMQKTIRMWLCKRRHKPRIDGLVKVGTLKKRLDKFNEVVSALKDGKPEVNRQIKNLEI 876
            + +QK+IRMW+C R+ KP+ + + KV +L+ +L+  +++V  +K  K    +Q+K LE 
Sbjct: 542 FVMIQKSIRMWICVRKFKPKYEMIQKVKSLQAQLNLMSQIVGQMKKDKETATKQVKELEA 721

Query: 877 SIDALMAKIKSTMMTREQIQKEYDALV 903
           ++ A + KI++T ++RE++ +  + L+
Sbjct: 722 ALTAYIHKIRTTNISREEMSRTTNQLM 802

 Score =  137 bits (344), Expect = 4e-32,   Method: Compositional matrix adjust.
 Identities = 69/116 (59%), Positives = 82/116 (70%)
 Frame = +2

Query: 1003 LAQECRDRELALRIAQNESELISDEAQGDMALRRGPAVQATKAAAGTKKHDLSKWKYAEL 1062
            L QE RDRELALR+A  +   + D +     L R   V+A + AA  KK+DL KWKYAEL
Sbjct: 1109 LDQEHRDRELALRLAMEDQNAVEDVSLPP-PLPRSDEVRAMQQAAANKKYDLQKWKYAEL 1285

Query: 1063 RDTINTSCDIELLAACREEFHRRLKVYHAWKSKNKKRNTETEQRAPKSVTDYDFAP 1118
            RD INTSCD+ELL +CREEFHRRLKVYHAWKSKNK+R  + E RAPK+V +    P
Sbjct: 1286 RDAINTSCDLELLDSCREEFHRRLKVYHAWKSKNKRRTDKGEHRAPKAVEEAGSVP 1453
>25922
          Length = 422

 Score =  113 bits (283), Expect = 5e-25,   Method: Compositional matrix adjust.
 Identities = 61/126 (48%), Positives = 79/126 (62%), Gaps = 2/126 (1%)
 Frame = -2

Query: 401 GTKGTVIKVPLKVEQANNARDALAKTVYSHLFDHVVNRVNQCFPFETS--SYFIGVLDIA 458
             KG ++   L V +++ ARDAL K +YS +F  +V+R+N       +  +  +GVLDI 
Sbjct: 379 AVKGDMVTTDLSVSESSYARDALCKALYSRMFSWLVHRINDSIKVRGAQRTKVMGVLDIY 200

Query: 459 GFEYFEHNSFEQFCINYCNEKLQQFFNERILKEEQELYQKEGLGVNEVHYVDNQDCIDLI 518
           GFE FE+NSFEQF INYCNEKLQQ F E  LKEEQE Y KEG+    V Y +N    +LI
Sbjct: 199 GFEVFENNSFEQFIINYCNEKLQQIFIELTLKEEQEEYIKEGIEWIHVEYFNNAVICELI 20

Query: 519 EVKLVG 524
           E  + G
Sbjct: 19  EKSVSG 2
>14047
          Length = 882

 Score =  110 bits (276), Expect = 3e-24,   Method: Compositional matrix adjust.
 Identities = 49/72 (68%), Positives = 59/72 (81%)
 Frame = -1

Query: 1172 AHFDGPWIARQMELHPDKPPILLVAGKDDMEMCELNLEETGLTRKRGAEILPRQFEEIWE 1231
            AHFDG WIARQME++PDKP ILL+AG DDM+MCEL+LEETGLTRK+GAEIL  +FEE W 
Sbjct: 882  AHFDGKWIARQMEVYPDKPAILLLAGVDDMQMCELSLEETGLTRKKGAEILENEFEEDWH 703

Query: 1232 RCGGIQYLQSAI 1243
            +  G  YL+  +
Sbjct: 702  KFNGATYLKKTL 667
>30605
          Length = 336

 Score = 97.4 bits (241), Expect = 3e-20,   Method: Composition-based stats.
 Identities = 55/113 (48%), Positives = 75/113 (66%), Gaps = 1/113 (0%)
 Frame = -3

Query: 311 LDDHGDFIRMCTAMKKIGLDDEGKLDLFRVVAGVLHLGNIDFE-EAGSTSGGCNLKNKSA 369
           LDD  DF     AM ++G+ D  K+ +F +VA VLHLGNI FE +   T GGC +  ++ 
Sbjct: 334 LDDVRDFKVCDEAMTRMGVSDADKMAIFMLVAAVLHLGNIAFEDDHDDTKGGCKVLEEAE 155

Query: 370 PSLEYCAELLGLDQDDLRVSLTTRVMLTTAGGTKGTVIKVPLKVEQANNARDA 422
            SL   A LLG+D+ +LR SLT+R+M   +GG KG+ IKVPLK  +A++ARDA
Sbjct: 154 DSLATAAVLLGVDKMELRDSLTSRIM--QSGGIKGSAIKVPLKPSEASSARDA 2
>05656
          Length = 1621

 Score = 32.3 bits (72), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 21/67 (31%), Positives = 32/67 (47%), Gaps = 12/67 (17%)
 Frame = -2

Query: 733  LFCKALFKALGLNEVD-------YKFGLTKVFFRPGKFAE-----FDQIMKSDPDHLAEL 780
            L CK  +K  GL  +D       ++FG  K  F P +F +     F  ++K  PD    L
Sbjct: 1368 LKCKPEYKVPGLYVIDSVVRQSRHQFGEDKDVFGP-RFTKNIVTTFQSLLKCPPDEKGRL 1192

Query: 781  VKRVNLW 787
            ++ +NLW
Sbjct: 1191 IRVLNLW 1171
>07324
          Length = 1291

 Score = 32.0 bits (71), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 18/50 (36%), Positives = 25/50 (50%)
 Frame = -1

Query: 1068 TSCDIELLAACREEFHRRLKVYHAWKSKNKKRNTETEQRAPKSVTDYDFA 1117
            T C +EL A   E+FH    VY   K+K K + T   Q   +  +DY F+
Sbjct: 304  TKCSVELNARVFEQFHDFKCVYTQLKNKTKNKQTNHPQNPMR*CSDYKFS 155
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|13386106|ref|NP_080899.1| nudix (nucleoside
diphosphate linked moiety X)-type motif 21 [Mus musculus]
         (227 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

06241                                                                 362   e-101
>06241
          Length = 2064

 Score =  362 bits (929), Expect = e-101,   Method: Compositional matrix adjust.
 Identities = 175/229 (76%), Positives = 193/229 (84%), Gaps = 10/229 (4%)
 Frame = +2

Query: 8   RSQTGWPR-------GVNQFGNKYIQQTKP---LTLERTINLYPLTNYTFGTKEPLYEKD 57
           R Q+GWPR       G + +   Y   T     LTLERT+NLYPL+NYTFGTKEPLYE+D
Sbjct: 11  RGQSGWPRDNKGPMSGGSSYSKAYNSSTSSPLNLTLERTVNLYPLSNYTFGTKEPLYERD 190

Query: 58  SSVAARFQRMREEFDKIGMRRTVEGVLIVHEHRLPHVLLLQLGTTFFKLPGGELNPGEDE 117
           SSV ARFQRMREEFD++GMRR+VEGVLIVHEH LPHVLLLQLGTTFFKLPGGEL  GE++
Sbjct: 191 SSVTARFQRMREEFDRMGMRRSVEGVLIVHEHGLPHVLLLQLGTTFFKLPGGELAAGEEQ 370

Query: 118 VEGLKRLMTEILGRQDGVLQDWVIDDCIGNWWRPNFEPPQYPYIPAHITKPKEHKKLFLV 177
             GLKRL+TE LGRQDG   +WV++D IGNWWRPNFEPPQYPYIPAHITKPKEHK+LFLV
Sbjct: 371 TAGLKRLLTETLGRQDGAPMNWVVEDTIGNWWRPNFEPPQYPYIPAHITKPKEHKRLFLV 550

Query: 178 QLQEKALFAVPKNYKLVAAPLFELYDNAPGYGPIISSLPQLLSRFNFIY 226
           QL EKALFAVP+NYKLVAAPLFELYDN+ GYGPIISSLPQ L RFNFIY
Sbjct: 551 QLPEKALFAVPRNYKLVAAPLFELYDNSAGYGPIISSLPQALGRFNFIY 697
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|22122825|ref|NP_666355.1| actin-related protein 2
[Mus musculus]
         (394 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

01436                                                                 365   e-101
04742                                                                 343   8e-95
39562                                                                 279   1e-75
02757                                                                 161   1e-46
12322                                                                 175   3e-44
00608                                                                 121   6e-28
32273                                                                  91   7e-19
19721                                                                  55   3e-17
13361                                                                  68   7e-12
36954                                                                  67   1e-11
11487                                                                  52   5e-07
18926                                                                  50   2e-06
>01436
          Length = 2563

 Score =  365 bits (937), Expect = e-101,   Method: Compositional matrix adjust.
 Identities = 174/201 (86%), Positives = 188/201 (93%)
 Frame = +3

Query: 189 ITRYLIKLLLLRGYAFNHSADFETVRMIKEKLCYVGYNIEQEQKLALETTVLVESYTLPD 248
           ITRYLIKLLLLRGYAFNHSADFETVRM+KEKLCY  Y++EQEQKLALETTVLVE Y LPD
Sbjct: 3   ITRYLIKLLLLRGYAFNHSADFETVRMLKEKLCYTAYDVEQEQKLALETTVLVEPYILPD 182

Query: 249 GRIIKVGGERFEAPEALFQPHLINVEGVGVAELLFNTIQAADIDTRSEFYKHIVLSGGST 308
           GR+IKVGGERFEAPEALFQPHLINV+GVGVAELLFNTIQAAD+D R +FYKHIVLSGGST
Sbjct: 183 GRVIKVGGERFEAPEALFQPHLINVDGVGVAELLFNTIQAADMDIRPDFYKHIVLSGGST 362

Query: 309 MYPGLPSRLERELKQLYLERVLKGDVEKLSKFKIRIEDPPRRKHMVFLGGAVLADIMKDK 368
           MYPGLPSRLERE+KQLYLERVL GD  +LSKFKIRIEDPPRRKHMVFLGG+V ADIMKDK
Sbjct: 363 MYPGLPSRLEREIKQLYLERVLXGDTSRLSKFKIRIEDPPRRKHMVFLGGSVXADIMKDK 542

Query: 369 DNFWMTRQEYQEKGVRVLEKL 389
           D+FWM R EY+E GV+VL+KL
Sbjct: 543 DDFWMMRSEYEEMGVKVLDKL 605
>04742
          Length = 2111

 Score =  343 bits (879), Expect = 8e-95,   Method: Compositional matrix adjust.
 Identities = 168/381 (44%), Positives = 238/381 (62%)
 Frame = +2

Query: 8   VVVCDNGTGFVKCGYAGSNFPEHIFPALVGRPIIRSTTKVGNIEIKDLMVGDEASELRSM 67
            +V DNG+G  K G+AG + P  +FP++VGRP  R    +  +  KD  VGDEA   R +
Sbjct: 113 ALVIDNGSGMCKAGFAGDDAPRAVFPSIVGRP--RHQGVMVGMGQKDSYVGDEAQSKRGI 286

Query: 68  LEVNYPMENGIVRNWDDMKHLWDYTFGPEKLNIDTRNCKILLTEPPMNPTKNREKIVEVM 127
           L + YP+E+GIV NWDDM+ +W +TF  E L +      +LLTE P+NP  NREK+ ++M
Sbjct: 287 LTLKYPIEHGIVTNWDDMEKIWHHTFYNE-LRVAPEEHPVLLTEAPLNPKANREKMTQIM 463

Query: 128 FETYQFSGVYVAIQAVLTLYAQXXXXXXXXXXXXXXXHICPVYEGFSLPHLTRRLDIAGR 187
           FET+    +YVAIQAVL+LYA                H  P+YEG++LPH   RLD+AGR
Sbjct: 464 FETFNSPAMYVAIQAVLSLYASGRTTGIVLDSGDGVXHTVPIYEGYALPHAISRLDLAGR 643

Query: 188 DITRYLIKLLLLRGYAFNHSADFETVRMIKEKLCYVGYNIEQEQKLALETTVLVESYTLP 247
           D+T YL+K+L  RGY+F  +A+ E VR IKEKLCYV  + EQE + A  ++ L +SY LP
Sbjct: 644 DLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMQTAASSSSLEKSYELP 823

Query: 248 DGRIIKVGGERFEAPEALFQPHLINVEGVGVAELLFNTIQAADIDTRSEFYKHIVLSGGS 307
           DG++I +G ERF  PEA+FQP  + +E  G  E  +N+I   D+D R + Y + VLSGGS
Sbjct: 824 DGQVITIGNERFRCPEAMFQPSFLGMESAGXHETTYNSIMKCDVDIRKDLYANTVLSGGS 1003

Query: 308 TMYPGLPSRLERELKQLYLERVLKGDVEKLSKFKIRIEDPPRRKHMVFLGGAVLADIMKD 367
           TMYPG+  R+++E+  L                KI+I  PP RK+ V++GG++LA +   
Sbjct: 1004TMYPGIADRMQKEITAL-----------APPTMKIKIIAPPERKYSVWIGGSILASLSTF 1150

Query: 368 KDNFWMTRQEYQEKGVRVLEK 388
           +   W+++QEY E G  ++ +
Sbjct: 1151Q-QMWISKQEYDESGPSIVHR 1210
>39562
          Length = 1438

 Score =  279 bits (714), Expect = 1e-75,   Method: Compositional matrix adjust.
 Identities = 136/311 (43%), Positives = 192/311 (61%)
 Frame = -2

Query: 78   IVRNWDDMKHLWDYTFGPEKLNIDTRNCKILLTEPPMNPTKNREKIVEVMFETYQFSGVY 137
            IV NWDDM+ +W +TF  E L +      +LLTE P+NP  NREK+ ++MFET+    +Y
Sbjct: 1437 IVTNWDDMEKIWHHTFYNE-LRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNSPAMY 1261

Query: 138  VAIQAVLTLYAQXXXXXXXXXXXXXXXHICPVYEGFSLPHLTRRLDIAGRDITRYLIKLL 197
            VAIQAVL+LYA                H  P+YEG++LPH   RLD+AGRD+T YL+K+L
Sbjct: 1260 VAIQAVLSLYASGRTTGIVLDSGDGVTHTVPIYEGYALPHAIMRLDLAGRDLTDYLMKIL 1081

Query: 198  LLRGYAFNHSADFETVRMIKEKLCYVGYNIEQEQKLALETTVLVESYTLPDGRIIKVGGE 257
              RGY+F  +A+ E VR IKEKL YV  + EQE   A  ++ L +SY LPDG++I +G E
Sbjct: 1080 TERGYSFTTTAEREIVRDIKEKLDYVALDFEQEMLTAASSSSLEKSYELPDGQVITIGNE 901

Query: 258  RFEAPEALFQPHLINVEGVGVAELLFNTIQAADIDTRSEFYKHIVLSGGSTMYPGLPSRL 317
            RF  PEA+FQP  + +E  G+ E  +N+I   D+D R + Y + VLSGGSTMYPG+  R+
Sbjct: 900  RFRCPEAMFQPSFLGMESAGIHETTYNSIMKCDVDIRKDLYANTVLSGGSTMYPGIADRM 721

Query: 318  ERELKQLYLERVLKGDVEKLSKFKIRIEDPPRRKHMVFLGGAVLADIMKDKDNFWMTRQE 377
            ++E+  L                KI+I  PP RK+ V++GG++LA  +      W+++QE
Sbjct: 720  QKEITAL-----------APPTMKIKIIAPPERKYSVWIGGSILAS-LSTFQQMWISKQE 577

Query: 378  YQEKGVRVLEK 388
            Y E G  ++ +
Sbjct: 576  YDESGPSIVHR 544
>02757
          Length = 1094

 Score =  161 bits (408), Expect(2) = 1e-46,   Method: Compositional matrix adjust.
 Identities = 73/158 (46%), Positives = 103/158 (65%)
 Frame = -2

Query: 167  CPVYEGFSLPHLTRRLDIAGRDITRYLIKLLLLRGYAFNHSADFETVRMIKEKLCYVGYN 226
            CP       P    RLD+AGRD+T YL+K+L  RGY+F  +A+ E V  IKEKLCYV  +
Sbjct: 1024 CPSTRVTPCPTAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVXDIKEKLCYVALD 845

Query: 227  IEQEQKLALETTVLVESYTLPDGRIIKVGGERFEAPEALFQPHLINVEGVGVAELLFNTI 286
             EQE   A  ++ L +SY LPDG++I +G ERF  PE+LFQP  + +E  G+ E  +N+I
Sbjct: 844  FEQEMATAASSSSLEKSYELPDGQVITIGNERFRCPESLFQPSFLGMESAGIHETTYNSI 665

Query: 287  QAADIDTRSEFYKHIVLSGGSTMYPGLPSRLERELKQL 324
               D+D R + Y + VLSGG+TM+PG+  R+++E+  L
Sbjct: 664  MKCDVDIRKDLYANTVLSGGTTMFPGIADRMQKEITAL 551

 Score = 43.1 bits (100), Expect(2) = 1e-46,   Method: Compositional matrix adjust.
 Identities = 18/51 (35%), Positives = 31/51 (60%)
 Frame = -3

Query: 338 SKFKIRIEDPPRRKHMVFLGGAVLADIMKDKDNFWMTRQEYQEKGVRVLEK 388
           S  KI+   PP RK+ V++GG++LA  +      W+++QEY E G  ++ +
Sbjct: 543 STMKIKXIAPPERKYSVWIGGSILAS-LSTFQQMWISKQEYDESGPSIVHR 394

 Score = 28.9 bits (63), Expect = 3.5,   Method: Compositional matrix adjust.
 Identities = 12/34 (35%), Positives = 16/34 (47%)
 Frame = -1

Query: 144  LTLYAQXXXXXXXXXXXXXXXHICPVYEGFSLPH 177
            L+LYA                H  P+YEG++LPH
Sbjct: 1094 LSLYASGRTTGIVLDSGDGVTHTVPIYEGYALPH 993
>12322
          Length = 849

 Score =  175 bits (443), Expect = 3e-44,   Method: Compositional matrix adjust.
 Identities = 95/227 (41%), Positives = 137/227 (60%), Gaps = 3/227 (1%)
 Frame = +1

Query: 165 HICPVYEGFSLPHLTRRLDIAGRDITRYLIKLLLLRGYAFNHSADFETVRMIKEKLCYVG 224
           H  PVYEGF++PH   R+D+AGRD+TRYL  LL   G   + +A+FE V+ IKE+ CY+ 
Sbjct: 7   HAVPVYEGFAMPHSIMRVDVAGRDVTRYLRLLLRKEGMDLHTTAEFEVVKHIKERTCYLS 186

Query: 225 YNIEQEQKLALETTVLVESYTLPDGRIIKVGGERFEAPEALFQPHLINVEGVGVAELLFN 284
            N  +E+ +  E      SYTLPDG  ++VG  RF APE LF+P LI  E  G+ E+L  
Sbjct: 187 INPLKEESVDTEKV----SYTLPDGNTVEVGPARFRAPELLFRPDLIGEECEGIHEVLSY 354

Query: 285 TIQAADIDTRSEFYKHIVLSGGSTMYPGLPSRLERELKQLYLERVLKGDVEKLSKFKIRI 344
           +IQ +D+D R   Y +IVLSGGST++ G   RL  ELK+L  + +           KIRI
Sbjct: 355 SIQKSDVDLRKTLYSNIVLSGGSTLFKGFGDRLLSELKKLAPKDI-----------KIRI 501

Query: 345 EDPPRRKHMVFLGGAVLADIMKDKDNF---WMTRQEYQEKGVRVLEK 388
             P  R +  ++G ++LA +    D F   W++++EY E+GV+ + +
Sbjct: 502 SAPQERLYSTWIGXSILASL----DTFRKMWVSKREYHEEGVKAIHR 630
>00608
          Length = 1930

 Score =  121 bits (303), Expect = 6e-28,   Method: Compositional matrix adjust.
 Identities = 103/330 (31%), Positives = 165/330 (50%), Gaps = 25/330 (7%)
 Frame = +3

Query: 78  IVRNWDDMKHLWDYTFGPEKLNIDTRNCKILLTEPPMNPTKNREKIVEVMFETYQFSGVY 137
           I+ +WD M+  ++     + L  +  +   LLTEPP+N  +NRE   E+MFE++   G+Y
Sbjct: 3   IIDDWDLMERFYEQVIF-KYLRAEPEDHYFLLTEPPLNTPENREYTAEIMFESFNVPGLY 179

Query: 138 VAIQAVLTLY--------AQXXXXXXXXXXXXXXXHICPVYEGFSLPHLTRRLDIAGRDI 189
           +A+QAVL L          +               H+ PV EG+ +    + + IAGRDI
Sbjct: 180 IAVQAVLALAASWTSRNVGERTLTGTVIDSGDGVTHVIPVAEGYVIGSCIKHIPIAGRDI 359

Query: 190 TRYLIKLLLLRGYAFNHSADFETVRMIKEKLCYVGYNIEQE-QKLALETTVLVESYTLPD 248
           T ++ +LL  R          ET + IKE+  YV  +I +E  K   + +  ++ Y   +
Sbjct: 360 TYFIQQLLREREVGIPPEQSLETAKAIKERFSYVCPDIAKEFSKYDTDPSKWMKKY---E 530

Query: 249 GR--------IIKVGGERFEAPEALFQPHLINVE-GVGVAELLFNTIQAADIDTRSEFYK 299
           GR         + VG ERF  PE  F P   N +  + +++++ + IQ   ID R   YK
Sbjct: 531 GRNTISKQLFSVDVGYERFLGPEIFFHPEFSNPDFTMPISDVVDDVIQNCPIDVRRGLYK 710

Query: 300 HIVLSGGSTMYPGLPSRLERELKQLYLERVLKGDVEKLSKFKIR---IEDPPRRKHM--- 353
           +IVLSGGSTM+     +++R++K++   R LK   E+LS+ +I+   IE      HM   
Sbjct: 711 NIVLSGGSTMFRDFGRKIQRDVKRVVDGR-LKAS-EELSQGRIKPKPIEVQVITHHMQRY 884

Query: 354 -VFLGGAVLADIMKDKDNFWMTRQEYQEKG 382
            V+ GG++LA    +      T+ +Y E G
Sbjct: 885 AVWFGGSMLAS-TPEFYQVCHTKADYDEHG 971
>32273
          Length = 265

 Score = 90.9 bits (224), Expect = 7e-19,   Method: Compositional matrix adjust.
 Identities = 34/82 (41%), Positives = 59/82 (71%)
 Frame = -2

Query: 67  MLEVNYPMENGIVRNWDDMKHLWDYTFGPEKLNIDTRNCKILLTEPPMNPTKNREKIVEV 126
           ++ + YPME+GIV++W+DM+ +W Y +  ++L   +    +LLTE P+NP +NREK  E+
Sbjct: 264 LMSIRYPMEHGIVKDWNDMERIWQYIYSKDQLQTFSEEHPVLLTEAPLNPRRNREKAAEI 85

Query: 127 MFETYQFSGVYVAIQAVLTLYA 148
            F+T+    +++++QAVL+LYA
Sbjct: 84  FFDTFNVPALFISMQAVLSLYA 19
>19721
          Length = 757

 Score = 55.1 bits (131), Expect(2) = 3e-17,   Method: Compositional matrix adjust.
 Identities = 35/111 (31%), Positives = 57/111 (51%), Gaps = 8/111 (7%)
 Frame = +3

Query: 211 ETVRMIKEKLCYVGYNIEQE-------QKLALETTVLVESYTLPDGRIIKVGGERFEAPE 263
           E  + IKE+  YV  +I +E        +  ++   +  S   PD     VG E+F  PE
Sbjct: 420 EAAKQIKERYSYVCPDIAKEFAKYDSDPEKWIKAHKMSGSSKYPDFSF-DVGYEKFLGPE 596

Query: 264 ALFQPHLINVE-GVGVAELLFNTIQAADIDTRSEFYKHIVLSGGSTMYPGL 313
             F+P  +N +    +++++   IQ+  ID+R   Y +IVLSGGS+M+  L
Sbjct: 597 VFFRPEFVNGDFQASISDVVDTVIQSCPIDSRRPLYNNIVLSGGSSMFKHL 749

 Score = 51.2 bits (121), Expect(2) = 3e-17,   Method: Compositional matrix adjust.
 Identities = 39/121 (32%), Positives = 60/121 (49%), Gaps = 8/121 (6%)
 Frame = +2

Query: 78  IVRNWDDMKHLWDYTFGPEKLNIDTRNCKILLTEPPMNPTKNREKIVEVMFETYQFSGVY 137
           +V +WD  +   +     + L  +  +   LLTEPP+N  +NRE   E+MFET+   G+Y
Sbjct: 2   VVEDWDLHERFMEQAIF-KYLRAEPEDHYFLLTEPPLNTPENREFTAEIMFETFNIPGLY 178

Query: 138 VAIQAVLTLYA--------QXXXXXXXXXXXXXXXHICPVYEGFSLPHLTRRLDIAGRDI 189
           +A+QAVL L A        +               H+ PV +G+ +    + + IAGRDI
Sbjct: 179 IAVQAVLALAASWTSRPPNERTLTGTVIDSGDGVTHVIPVVDGYVIGSAIKHIPIAGRDI 358

Query: 190 T 190
           T
Sbjct: 359 T 361
>13361
          Length = 1217

 Score = 67.8 bits (164), Expect = 7e-12,   Method: Compositional matrix adjust.
 Identities = 47/154 (30%), Positives = 76/154 (49%), Gaps = 12/154 (7%)
 Frame = +3

Query: 221 CYVGYNIEQE-QKLALETTVLVESYT-----LPDGRIIKVGGERFEAPEALFQPHLINVE 274
           CY+  +I +E  K   E +  + +YT           + VG ERF  PE  F P   N +
Sbjct: 42  CYICPDIAKEFAKYDSEPSKWIRNYTGMNTVTKQAFNVDVGYERFLGPEIFFHPEFSNPD 221

Query: 275 -GVGVAELLFNTIQAADIDTRSEFYKHIVLSGGSTMYPGLPSRLERELK-----QLYLER 328
             + ++E++ N IQ   ID R   Y +IVLSGGSTM+     RL+R++K     +L +  
Sbjct: 222 FTIPLSEIVDNVIQNCPIDVRRHLYNNIVLSGGSTMFKDFGRRLQRDIKRSVDTRLRISE 401

Query: 329 VLKGDVEKLSKFKIRIEDPPRRKHMVFLGGAVLA 362
            L     K     +++     +++ V+ GG++LA
Sbjct: 402 NLSEGRIKPKPIDVQVITHHMQRYAVWFGGSMLA 503
>36954
          Length = 892

 Score = 67.0 bits (162), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 52/193 (26%), Positives = 87/193 (45%), Gaps = 9/193 (4%)
 Frame = -1

Query: 8   VVVCDNGTGFVKCGYAGSNFPEHIFPALVG-RPIIRST--TKVGNI----EIKDLMVGDE 60
            +V D G+   + GYAG + P+   P  VG    I +T  T  G+     E K L+    
Sbjct: 805 ALVFDIGSYSFRAGYAGEDTPKAEIPTHVGVMEDIETTMDTDGGDAPPQPEKKYLIDTVY 626

Query: 61  ASELRSMLEVNYPMENGIVRNWDDMKHLWDYTFGPEKLNIDTRNC--KILLTEPPMNPTK 118
               R  + +N  +++G+V +WD  + + DY +     +I + +C   +L++EP  N   
Sbjct: 625 MKHPRKGMHLNSFLKDGMVEDWDMFEKVIDYAY---NRSIKSESCLHPLLMSEPAWNTKA 455

Query: 119 NREKIVEVMFETYQFSGVYVAIQAVLTLYAQXXXXXXXXXXXXXXXHICPVYEGFSLPHL 178
            REK+ E+MFE Y     ++   +VL+ +A                   PVY+G+ L   
Sbjct: 454 KREKLTEIMFEKYNIPAFFLRKNSVLSAFANGRSTALILDSGATHTSAVPVYDGYVLTQG 275

Query: 179 TRRLDIAGRDITR 191
             +  +AG  I R
Sbjct: 274 IVKSPLAGDFIAR 236
>11487
          Length = 771

 Score = 51.6 bits (122), Expect = 5e-07,   Method: Compositional matrix adjust.
 Identities = 21/47 (44%), Positives = 33/47 (70%)
 Frame = -1

Query: 280 ELLFNTIQAADIDTRSEFYKHIVLSGGSTMYPGLPSRLERELKQLYL 326
           E  +N+I   D+D R + Y + VLSGG+TM+PG+  R+++E  QL+L
Sbjct: 771 ETAYNSIMKCDVDIRKDLYANTVLSGGTTMFPGIADRMQKE-SQLWL 634

 Score = 37.0 bits (84), Expect = 0.013,   Method: Compositional matrix adjust.
 Identities = 22/76 (28%), Positives = 37/76 (48%), Gaps = 1/76 (1%)
 Frame = -2

Query: 314 PSRLERELKQL-YLERVLKGDVEKLSKFKIRIEDPPRRKHMVFLGGAVLADIMKDKDNFW 372
           P  LE  L  L  L    K      S  + +    P RK+ V++GG++LA +   +   W
Sbjct: 707 PCCLEARLCSLALLTECRKNHSSGSSHHEDQDHRSPERKYSVWIGGSILASLSTFQ-QMW 531

Query: 373 MTRQEYQEKGVRVLEK 388
           +++QEY E G  ++ +
Sbjct: 530 ISKQEYDESGPSIVHR 483
>18926
          Length = 478

 Score = 49.7 bits (117), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 32/128 (25%), Positives = 56/128 (43%), Gaps = 1/128 (0%)
 Frame = +1

Query: 262 PEALFQPHLINVEGVGVAELLFNTIQAADIDTRSEFYKHIVLSGGSTMYPGLPSRLEREL 321
           P +   P    V GVG   ++  ++   DID R   Y  ++  GG+++  G   RL R+L
Sbjct: 58  PPSSRNPKATPVLGVG--HVVTTSVGMCDIDIRPSLYGGVIAVGGNSLIQGFTERLNRDL 231

Query: 322 KQLYLERVLKGDVEKLSKFK-IRIEDPPRRKHMVFLGGAVLADIMKDKDNFWMTRQEYQE 380
                            + K I       R+   ++GG++LA  +      W+++QEY+E
Sbjct: 232 SN---------KTPPSMRLKIIAAASTAERRFSSWIGGSILAS-LGSFQQMWVSKQEYEE 381

Query: 381 KGVRVLEK 388
            G   +E+
Sbjct: 382 GGKSCVER 405
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31981534|ref|NP_035314.2| proteasome (prosome,
macropain) subunit, alpha type 3 [Mus musculus]
         (255 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

17033                                                                 363   e-101
20771                                                                 132   1e-31
02448                                                                 124   3e-29
24591                                                                 124   4e-29
14551                                                                 115   2e-26
00789                                                                 103   5e-23
04255                                                                  79   7e-21
37174                                                                  32   0.18 
16035                                                                  30   0.97 
>17033
          Length = 2217

 Score =  363 bits (932), Expect = e-101,   Method: Compositional matrix adjust.
 Identities = 171/232 (73%), Positives = 205/232 (88%)
 Frame = -3

Query: 1    MSSIGTGYDLSASTFSPDGRVFQVEYAMKAVENSSTAIGIRCKDGVVFGVEKLVLSKLYE 60
            MSSIGTGYDLSAS FSPDGRVFQVEYA KAVENS TAIGIR KDGVV GVEKLV SKLYE
Sbjct: 2170 MSSIGTGYDLSASHFSPDGRVFQVEYAQKAVENSGTAIGIRGKDGVVMGVEKLVTSKLYE 1991

Query: 61   EGSNKRLFNVDRHVGMAVAGLLADARSLADIAREEASNFRSNFGYNIPLKHLADRVAMYV 120
            +G+NKRLFN+DRH+G AVAGLLADAR L + A+EE+SN+R N+G  +PLK+L DRVA YV
Sbjct: 1990 QGANKRLFNIDRHIGGAVAGLLADARQLMERAKEESSNYRFNYGSPVPLKYLTDRVAGYV 1811

Query: 121  HAYTLYSAVRPFGCSFMLGSYSANDGAQLYMIDPSGVSYGYWGCAIGKRRQAAKTEIEKL 180
            HAYTL+SAVRPFG S ++ SY A  G Q+++++PSGVS+GY+GCAIGK +Q AKTEIEKL
Sbjct: 1810 HAYTLHSAVRPFGTSMIVASYDAV-GPQMFLVEPSGVSWGYYGCAIGKAKQTAKTEIEKL 1634

Query: 181  QMKEMTCRDVVKEVAKIIYIVHDEVKDKAFELELSWVGELTKGRHEIVPKDI 232
            +MK++T +D+VKEVA+IIY+VHDEVKDK+FELELSWVGE T G+H++VPKD+
Sbjct: 1633 KMKDLTMQDLVKEVARIIYVVHDEVKDKSFELELSWVGEATGGKHQLVPKDV 1478
>20771
          Length = 674

 Score =  132 bits (332), Expect = 1e-31,   Method: Compositional matrix adjust.
 Identities = 72/190 (37%), Positives = 113/190 (59%), Gaps = 5/190 (2%)
 Frame = +2

Query: 8   YDLSASTFSPDGRVFQVEYAMKAVENSSTAIGIRCKDGVVFGVEKLVLSKLYEEGSNKRL 67
           YD   +TFSP+GR+FQVEYA++A++  STAIGI+  +GVV  VEK V S L E  S +++
Sbjct: 101 YDRGVNTFSPEGRLFQVEYAIEAIKLGSTAIGIQTNEGVVLAVEKRVTSSLIEPTSIEKI 280

Query: 68  FNVDRHVGMAVAGLLADARSLADIAREEASNFRSNFGYNIPLKHLADRVAMYVHAY---- 123
             VD+H+G A++GL+AD+R+L D AR EA N    +  N+ ++ +   V+    A+    
Sbjct: 281 MEVDKHIGCAMSGLIADSRTLIDRARVEAQNHWFTYNENMSVESVTQAVSNLALAFGDDD 460

Query: 124 -TLYSAVRPFGCSFMLGSYSANDGAQLYMIDPSGVSYGYWGCAIGKRRQAAKTEIEKLQM 182
               +  RPFG + ++    +N G +L+ +DPSG    Y   AIG   + A+  +++   
Sbjct: 461 PDPGAMSRPFGVALLIAGVDSN-GPRLFHMDPSGTFIQYDAKAIGSGSEGAQQALQEQYH 637

Query: 183 KEMTCRDVVK 192
           K +T +D  K
Sbjct: 638 KSITLKDACK 667
>02448
          Length = 1302

 Score =  124 bits (312), Expect = 3e-29,   Method: Compositional matrix adjust.
 Identities = 68/196 (34%), Positives = 109/196 (55%)
 Frame = +2

Query: 2   SSIGTGYDLSASTFSPDGRVFQVEYAMKAVENSSTAIGIRCKDGVVFGVEKLVLSKLYEE 61
           +++   YD + + FSPDG +FQVEYA +AV+  STA+G+R  + VV GVEK  ++KL EE
Sbjct: 245 ATMSDRYDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGNNLVVLGVEKKAVAKLQEE 424

Query: 62  GSNKRLFNVDRHVGMAVAGLLADARSLADIAREEASNFRSNFGYNIPLKHLADRVAMYVH 121
            + +++  +D HV +A AGL ADAR L + AR E  + +      + ++++   +A    
Sbjct: 425 RTVRKIALLDEHVALAFAGLTADARILINRARIECQSHKLTVEDPVTVEYITRHIAQLKQ 604

Query: 122 AYTLYSAVRPFGCSFMLGSYSANDGAQLYMIDPSGVSYGYWGCAIGKRRQAAKTEIEKLQ 181
            YT  +  RPFG S ++  +  +    LY  DPSG  + +    IG+  +  +  +EK  
Sbjct: 605 KYTQSNGRRPFGLSSLIIGFDYDGSPHLYQTDPSGTYHEWKANTIGRNAKTVREFLEKHY 784

Query: 182 MKEMTCRDVVKEVAKI 197
             E+   D  KE  K+
Sbjct: 785 TDEVAASD--KETIKL 826
>24591
          Length = 1801

 Score =  124 bits (311), Expect = 4e-29,   Method: Compositional matrix adjust.
 Identities = 68/190 (35%), Positives = 106/190 (55%)
 Frame = +1

Query: 8   YDLSASTFSPDGRVFQVEYAMKAVENSSTAIGIRCKDGVVFGVEKLVLSKLYEEGSNKRL 67
           YD + + FSPDG +FQVEYA +AV+  STA+G+R  + VV GVEK  ++KL EE + +++
Sbjct: 40  YDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGDNLVVLGVEKKAVAKLQEERTVRKI 219

Query: 68  FNVDRHVGMAVAGLLADARSLADIAREEASNFRSNFGYNIPLKHLADRVAMYVHAYTLYS 127
             +D HV +A AGL ADAR L + AR E  + +      + ++++   +A     YT  +
Sbjct: 220 ALLDEHVALAFAGLTADARILINRARIECQSHKLTVEDPVTVEYITRHIAQLKQKYTQSN 399

Query: 128 AVRPFGCSFMLGSYSANDGAQLYMIDPSGVSYGYWGCAIGKRRQAAKTEIEKLQMKEMTC 187
             RPFG S ++  +  +    LY  DPSG  + +    IG+  +  +  +EK    E+  
Sbjct: 400 GRRPFGLSSLIIGFDYDGTPHLYQTDPSGTYHEWKANTIGRNAKTVREFLEKHYTDEVAA 579

Query: 188 RDVVKEVAKI 197
            D  KE  K+
Sbjct: 580 SD--KETIKL 603
>14551
          Length = 1344

 Score =  115 bits (287), Expect = 2e-26,   Method: Compositional matrix adjust.
 Identities = 62/191 (32%), Positives = 100/191 (52%), Gaps = 1/191 (0%)
 Frame = +3

Query: 2   SSIGTGYDLSASTFSPDGRVFQVEYAMKAVENSSTAIGIRCKDGVVFGVEKLVLSKLYEE 61
           S++   Y  S +TFSP G++ Q+EYA+ AV   + ++GI+  +GVV   EK   S  Y+E
Sbjct: 135 SNMTERYSFSLTTFSPSGKLVQIEYALAAVGAGAPSVGIKATNGVVLATEKKQKSVXYDE 314

Query: 62  GSNKRLFNVDRHVGMAVAGLLADARSLADIAREEASNFRSNFGYNIPLKHLADRVAMYVH 121
            S  ++  + +++G+  +G+  D R L   AR+ A  ++  +   IP   L  RVA  + 
Sbjct: 315 HSINKVETITKNIGIVYSGMGPDYRVLCRRARKLAEQYKRVYNEQIPTAQLVQRVAAVMQ 494

Query: 122 AYTLYSAVRPFGCSFMLGSYSANDGAQ-LYMIDPSGVSYGYWGCAIGKRRQAAKTEIEKL 180
            +T    VRPFG S ++  +  +D    LY  DPSG  + +   A+GK     KT +EK 
Sbjct: 495 EFTQSGGVRPFGVSLLMAGWDEDDKKPFLYQCDPSGAYFAWKATAMGKNHINGKTFLEKR 674

Query: 181 QMKEMTCRDVV 191
             + +   D V
Sbjct: 675 YSETLELEDAV 707
>00789
          Length = 1584

 Score =  103 bits (258), Expect = 5e-23,   Method: Compositional matrix adjust.
 Identities = 60/184 (32%), Positives = 97/184 (52%), Gaps = 1/184 (0%)
 Frame = +1

Query: 2   SSIGTGYDLSASTFSPDGRVFQVEYAMKAVENSSTAIGIRCKDGVVFGVEKLVLSKLYEE 61
           S +   YD   + FSP+GR++QVEYAM+A+ ++ T +GI  KDG+V   E+   +KL +E
Sbjct: 16  SKMARRYDSRTTIFSPEGRLYQVEYAMEAIGHAGTCLGILAKDGIVLAAERRNTNKLLDE 195

Query: 62  GS-NKRLFNVDRHVGMAVAGLLADARSLADIAREEASNFRSNFGYNIPLKHLADRVAMYV 120
            S +++++ +   +  +VAG+ +DA  L +  R  A  +   +   IP + +   +    
Sbjct: 196 VSYSEKIYRLSDDMACSVAGITSDANVLTNELRLIAQRYLLQYQEPIPCEQVVATLCDIK 375

Query: 121 HAYTLYSAVRPFGCSFMLGSYSANDGAQLYMIDPSGVSYGYWGCAIGKRRQAAKTEIEKL 180
            AYT +   RPFG S +   +  + G QLY  DPSG +YG W         A    + K 
Sbjct: 376 QAYTQFGGKRPFGVSILYMGWDKHYGFQLYQSDPSG-NYGGWKATCIGNNSANAVSLLKQ 552

Query: 181 QMKE 184
           + KE
Sbjct: 553 EYKE 564
>04255
          Length = 1758

 Score = 79.3 bits (194), Expect(2) = 7e-21,   Method: Compositional matrix adjust.
 Identities = 38/126 (30%), Positives = 67/126 (53%)
 Frame = -2

Query: 54   VLSKLYEEGSNKRLFNVDRHVGMAVAGLLADARSLADIAREEASNFRSNFGYNIPLKHLA 113
            V  KL +  +   L+++   +G  + G++AD++S    AR EA+ ++  +GY+IP+  L 
Sbjct: 1466 VPDKLLDPTTVTHLYSLTERIGCVMTGMIADSQSQVQRARYEAAKWKYTYGYDIPVDMLC 1287

Query: 114  DRVAMYVHAYTLYSAVRPFGCSFMLGSYSANDGAQLYMIDPSGVSYGYWGCAIGKRRQAA 173
             R+A     YT  + +RP GC  +L  Y    G ++Y  DP+G   G+   + G ++  A
Sbjct: 1286 KRIANINQVYTQSAEMRPLGCCMILIGYDDEKGPEVYKTDPAGYYCGFKATSAGSKQLEA 1107

Query: 174  KTEIEK 179
               +EK
Sbjct: 1106 NGFLEK 1089

 Score = 38.1 bits (87), Expect(2) = 7e-21,   Method: Compositional matrix adjust.
 Identities = 17/39 (43%), Positives = 25/39 (64%), Gaps = 1/39 (2%)
 Frame = -3

Query: 15   FSPDGRVFQVEYAMKAVENSS-TAIGIRCKDGVVFGVEK 52
             SP+GR++QVEYA KA+     T++ +R KD  V   +K
Sbjct: 1585 LSPEGRLYQVEYAFKAINQGGLTSVAVRGKDSAVIVTQK 1469
>37174
          Length = 146

 Score = 32.3 bits (72), Expect = 0.18,   Method: Composition-based stats.
 Identities = 13/33 (39%), Positives = 21/33 (63%)
 Frame = +1

Query: 17 PDGRVFQVEYAMKAVENSSTAIGIRCKDGVVFG 49
          P  ++ Q+EYA+ AV   +  +GI+  +GVV G
Sbjct: 43 PTAQLVQIEYALAAVGAGAPVVGIKATNGVVLG 141
>16035
          Length = 1206

 Score = 30.0 bits (66), Expect = 0.97,   Method: Compositional matrix adjust.
 Identities = 14/46 (30%), Positives = 25/46 (54%), Gaps = 8/46 (17%)
 Frame = +2

Query: 137  MLGSYSANDGAQLYM--------IDPSGVSYGYWGCAIGKRRQAAK 174
            M G  +A++G  +YM        + P+G SYG +G  I  + ++A+
Sbjct: 1010 MFGGAAADEGKAMYMDAFRRLNSLGPAGSSYGQFGSTIQPQNESAE 1147
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|51491845|ref|NP_001003908.1| clathrin, heavy
polypeptide (Hc) [Mus musculus]
         (1675 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

32593                                                                 305   e-101
30738                                                                 200   4e-51
34414                                                                 195   1e-49
23440                                                                  32   1.7  
14635                                                                  31   3.9  
>32593
          Length = 904

 Score =  305 bits (781), Expect(2) = e-101,   Method: Composition-based stats.
 Identities = 139/175 (79%), Positives = 155/175 (88%)
 Frame = +2

Query: 83  KAGKTLQIFNIEMKSKMKAHTMTDDVTFWKWISLNTVALVTDNAVYHWSMEGESQPVKMF 142
           ++GKTLQIFNIEMKSKMKAHTMT++V FWKWIS+N + LVTD AVYHW+MEG+SQP K+F
Sbjct: 119 QSGKTLQIFNIEMKSKMKAHTMTEEVIFWKWISVNIIGLVTDQAVYHWTMEGDSQPQKVF 298

Query: 143 DRHSSLAGCQIINYRTDAKQKWLLLTGISAQQNRVVGAMQLYSVDRKVSQPIEGHAASFA 202
           DRHS+L GCQIINYRTDAKQ+WLLL GISAQQNRVVGAMQLYSV+RKVSQPIEGHAA+FA
Sbjct: 299 DRHSNLTGCQIINYRTDAKQQWLLLVGISAQQNRVVGAMQLYSVERKVSQPIEGHAAAFA 478

Query: 203 QFKMEGNAEESTLFCFAVRGQAGGKLHIIEVGTPPTGNQPFPKKAVDVFFPPEAQ 257
              +EGN + STLF FAVRG  GGKLH+IEVG PP GNQ F KKAVDVFFP EAQ
Sbjct: 479 THTVEGNPQPSTLFMFAVRGPQGGKLHVIEVGQPPQGNQAFTKKAVDVFFPVEAQ 643

 Score = 84.0 bits (206), Expect(2) = e-101,   Method: Composition-based stats.
 Identities = 40/43 (93%), Positives = 41/43 (95%)
 Frame = +3

Query: 44 VGEQAQVVIIDMNDPSNPIRRPISADSAIMNPASKVIALKAGK 86
          VGE AQVVIIDMND +NPIRRPISADSAIMNPASKVIALKAGK
Sbjct: 3  VGETAQVVIIDMNDSANPIRRPISADSAIMNPASKVIALKAGK 131

 Score =  167 bits (422), Expect = 5e-41,   Method: Composition-based stats.
 Identities = 81/124 (65%), Positives = 93/124 (75%)
 Frame = +1

Query: 221 RGQAGGKLHIIEVGTPPTGNQPFPKKAVDVFFPPEAQNDFPVAMQISEKHDVVFLITKYG 280
           +G  GG+      GT  +      +++     P    +DFPVAMQ S+KH VVFLITKYG
Sbjct: 532 QGPTGGQAPCD*GGTASSRQPGVHQESCGCVLPCGGSDDFPVAMQTSQKHGVVFLITKYG 711

Query: 281 YIHLYDLETGTCIYMNRISGETIFVTAPHEATAGIIGVNRKGQVLSVCVEEENIIPYITN 340
           YIHLYD+ETGTCIYMNRISG+TIFVTA HEAT+GIIGVNRKGQVLSV VEEENI+ YITN
Sbjct: 712 YIHLYDIETGTCIYMNRISGDTIFVTASHEATSGIIGVNRKGQVLSVSVEEENIVSYITN 891

Query: 341 VLQN 344
            LQN
Sbjct: 892 TLQN 903
>30738
          Length = 425

 Score =  200 bits (509), Expect = 4e-51,   Method: Compositional matrix adjust.
 Identities = 100/136 (73%), Positives = 105/136 (77%)
 Frame = +1

Query: 375 GNYSEAAKVAANAPKGILRTPDTIRRFQSVPAQPGQTSPLLQYFGILLDQGQLNKYESLE 434
             Y EAAK    APKGILRTP TI+RFQ VP   G TSPLLQYFGILLD+GQLNKYESLE
Sbjct: 19  AQYQEAAKSPPRAPKGILRTPQTIQRFQQVPTTSG-TSPLLQYFGILLDKGQLNKYESLE 195

Query: 435 LCRPVLQQGRXXXXXXXXXXXXXXCSEELGDLVKSVDPTLALSVYLRANVPNKVIQCFAE 494
           LCRPVLQQGR              C EELGDLVK+ DPTLALSVYLRANVP KVIQCFAE
Sbjct: 196 LCRPVLQQGRKQLLEKWLKEDKLECCEELGDLVKTADPTLALSVYLRANVPQKVIQCFAE 375

Query: 495 TGQVQKIVLYAKKVGY 510
           TGQ QKI+LYAKKVG+
Sbjct: 376 TGQFQKIILYAKKVGF 423
>34414
          Length = 384

 Score =  195 bits (496), Expect = 1e-49,   Method: Composition-based stats.
 Identities = 96/127 (75%), Positives = 104/127 (81%)
 Frame = +3

Query: 380 AAKVAANAPKGILRTPDTIRRFQSVPAQPGQTSPLLQYFGILLDQGQLNKYESLELCRPV 439
           AAKVAA+APKGILRTP TI+RFQ VP+  G TSPLLQYFGILLD+GQLNKYESLELCRPV
Sbjct: 3   AAKVAASAPKGILRTPQTIQRFQQVPSTAGTTSPLLQYFGILLDKGQLNKYESLELCRPV 182

Query: 440 LQQGRXXXXXXXXXXXXXXCSEELGDLVKSVDPTLALSVYLRANVPNKVIQCFAETGQVQ 499
           LQQGR              C EELGDLVK+ DPTLALSVYLRA+VP KVIQCFAETGQ Q
Sbjct: 183 LQQGRKQLLEKWLKEDKLECCEELGDLVKAADPTLALSVYLRASVPQKVIQCFAETGQFQ 362

Query: 500 KIVLYAK 506
           KI+LY+K
Sbjct: 363 KIILYSK 383
>23440
          Length = 2048

 Score = 32.3 bits (72), Expect = 1.7,   Method: Compositional matrix adjust.
 Identities = 26/87 (29%), Positives = 44/87 (50%), Gaps = 6/87 (6%)
 Frame = +3

Query: 576 SEGPLQTRLLEMNLMHAPQVADAILGNQMFTHYD-RAHIAQL-CEKAGLLQRA-LEHFTD 632
           S G LQ  + + N+ H P  AD I      + ++   +I++L C+   LL +  L+H T 
Sbjct: 279 SRGCLQRHMNKCNMYHPP--ADEIYRQGSLSVFEVDGNISKLYCQNLCLLAKLFLDHKTL 452

Query: 633 LYDIKRAVVHTHLLNPEW---LVNYFG 656
            YD++  + +   +N EW   +V YF 
Sbjct: 453 YYDVEPFLFYVLTVNDEWGSHIVGYFS 533
>14635
          Length = 1002

 Score = 31.2 bits (69), Expect = 3.9,   Method: Composition-based stats.
 Identities = 17/56 (30%), Positives = 31/56 (55%)
 Frame = -3

Query: 372 FAQGNYSEAAKVAANAPKGILRTPDTIRRFQSVPAQPGQTSPLLQYFGILLDQGQL 427
           F+  ++S  A +    P G+L TP+ +++  SV + P    P+L  + +L+  GQL
Sbjct: 172 FSPPSFSTTAPLCRPLPLGVLHTPEIVKQSFSVKSAP---KPVLMKWFLLVFPGQL 14
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6754724|ref|NP_034947.1| proteasome (prosome,
macropain) 26S subunit, non-ATPase, 7 [Mus musculus]
         (321 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

14533                                                                 364   e-101
20649                                                                 210   7e-55
13866                                                                  42   5e-04
02425                                                                  30   1.6  
05855                                                                  29   2.5  
15076                                                                  28   5.2  
>14533
          Length = 1436

 Score =  364 bits (935), Expect = e-101,   Method: Compositional matrix adjust.
 Identities = 170/230 (73%), Positives = 200/230 (86%)
 Frame = -2

Query: 54   FAVPFDEDDKDDSVWFLDHDYLENMYGMFKKVNARERIVGWYHTGPKLHKNDIAINELMK 113
            F  PFDEDDKD +VWFLDHDYLENMYGMFKKVNARE++VGWYHTGPKLH NDIAINE+++
Sbjct: 1306 FFSPFDEDDKDRNVWFLDHDYLENMYGMFKKVNAREKVVGWYHTGPKLHHNDIAINEMIR 1127

Query: 114  RYCPNSVLVIIDVKPKDLGLPTEAYISVEEVHDDGTPTSKTFEHVTSEIXXXXXXXXXXX 173
            +YCPNSVLV+ID KPKDLGLPTE YI+VEEVHDDG+PT+KTF+HV S+I           
Sbjct: 1126 KYCPNSVLVVIDAKPKDLGLPTEGYIAVEEVHDDGSPTTKTFDHVPSDIGAEEAEEVGVE 947

Query: 174  HLLRDIKDTTVGTLSQRITNQVHGLKGLNSKLLDIRSYLEKVASGKLPINHQIIYQLQDV 233
            HLLRDIKDTTVGTLSQRIT+Q+ GLKGL+S + +I SY+ KV SGKLPINHQ++Y LQD+
Sbjct: 946  HLLRDIKDTTVGTLSQRITSQLMGLKGLHSHIREIDSYVGKVVSGKLPINHQVVYLLQDI 767

Query: 234  FNLLPDASLQEFVKAFYLKTNDQMVVVYLASLIRSVVALHNLINNKIANR 283
            FNLLPD  L +FV++ ++KTNDQM+VVYLASLIRSV+ALHNLI+NKI NR
Sbjct: 766  FNLLPDVKLADFVRSMHIKTNDQMLVVYLASLIRSVIALHNLIDNKIQNR 617
>20649
          Length = 549

 Score =  210 bits (534), Expect = 7e-55,   Method: Compositional matrix adjust.
 Identities = 95/114 (83%), Positives = 107/114 (93%)
 Frame = -3

Query: 21  DHFNRIGKVGNQKRVVGVLLGSWQKKVLDVSNSFAVPFDEDDKDDSVWFLDHDYLENMYG 80
           DHFNR+GKVGN KRVVGVLLG+ +  +LDVSNSFAVPFDEDDKD +VWFLDHDYLENMYG
Sbjct: 343 DHFNRMGKVGNVKRVVGVLLGANKGGILDVSNSFAVPFDEDDKDRNVWFLDHDYLENMYG 164

Query: 81  MFKKVNARERIVGWYHTGPKLHKNDIAINELMKRYCPNSVLVIIDVKPKDLGLP 134
           MFKKVNARE++VGWYHTGPKLH NDIAINE++++YCPNSVLV+ID KPKDLGLP
Sbjct: 163 MFKKVNAREKVVGWYHTGPKLHHNDIAINEMIRKYCPNSVLVVIDAKPKDLGLP 2
>13866
          Length = 855

 Score = 41.6 bits (96), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 31/107 (28%), Positives = 50/107 (46%), Gaps = 8/107 (7%)
 Frame = -2

Query: 27  GKVGNQKRVVGVLLGS----WQKKVLDVSNSFAVPFDEDDKDDSVWFLDHDYLENMYGMF 82
           G+ G    V+G++LG     +  +V+DV   FA+P  +     SV  +D  +   M  M 
Sbjct: 656 GRAGVPMEVMGLMLGEFVDDYTVRVIDV---FAMP--QSGTGVSVEAVDPVFQAKMLDML 492

Query: 83  KKVNARERIVGWYHTGPK----LHKNDIAINELMKRYCPNSVLVIID 125
           K+    E +VGWYH+ P     L   DI   +  +     +V V++D
Sbjct: 491 KQTGRPEMVVGWYHSHPGFGCWLSGVDINTQQSFEALSERAVAVVVD 351
>02425
          Length = 1374

 Score = 29.6 bits (65), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 13/42 (30%), Positives = 23/42 (54%)
 Frame = -3

Query: 225 QIIYQLQDVFNLLPDASLQEFVKAFYLKTNDQMVVVYLASLI 266
           +IIY LQ++F     + +  + K  YLKT++   ++Y    I
Sbjct: 652 RIIYSLQELFIYFSLSFINSYSKNIYLKTSNLGTIIYFCCFI 527
>05855
          Length = 1374

 Score = 28.9 bits (63), Expect = 2.5,   Method: Compositional matrix adjust.
 Identities = 17/64 (26%), Positives = 30/64 (46%)
 Frame = +3

Query: 195 VHGLKGLNSKLLDIRSYLEKVASGKLPINHQIIYQLQDVFNLLPDASLQEFVKAFYLKTN 254
           + GLK   +KL    + + K  +     NH+II+  +  FN+  +     F+K F  KT 
Sbjct: 378 IAGLKKTANKLTYEHANMHKRTNQSYQTNHKIIFLYKRGFNIYFNRGKHRFIKWF*KKTC 557

Query: 255 DQMV 258
             ++
Sbjct: 558 GGLI 569
>15076
          Length = 2760

 Score = 28.1 bits (61), Expect = 5.2,   Method: Compositional matrix adjust.
 Identities = 11/30 (36%), Positives = 17/30 (56%)
 Frame = -2

Query: 215 VASGKLPINHQIIYQLQDVFNLLPDASLQE 244
           V  G  P+NHQ++Y   DV + L   +L +
Sbjct: 248 VNHGFFPVNHQLLYDFLDVLHFLALVTLDD 159
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|7948999|ref|NP_058044.1| peroxiredoxin 4 [Mus
musculus]
         (274 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

09130                                                                 363   e-101
10721                                                                 280   3e-76
09123                                                                  62   3e-10
>09130
          Length = 1000

 Score =  363 bits (932), Expect = e-101,   Method: Compositional matrix adjust.
 Identities = 169/222 (76%), Positives = 191/222 (86%)
 Frame = +1

Query: 51  ENECHFYAGGQVYPGEASRVSVADHSLHLSKAKISKPAPYWEGTAVINGEFKELKLTDYR 110
           E  C+ YAGG V+P E  R S   HS+  S+A ISKPAP W GTAVI+GEFK++KL+D+R
Sbjct: 106 EESCYSYAGGSVFPQETRRTS--GHSIQWSQAVISKPAPDWNGTAVIDGEFKDIKLSDFR 279

Query: 111 GKYLVFFFYPLDFTFVCPTEIIAFGDRIEEFKSINTEVVACSVDSQFTHLAWINTPRRQG 170
           GKYLVFFFYPLDFTFVCPTEI+AF D + +FKSINTEVVACSVDSQFTHLAWINTPR QG
Sbjct: 280 GKYLVFFFYPLDFTFVCPTEIVAFSDNVGKFKSINTEVVACSVDSQFTHLAWINTPRNQG 459

Query: 171 GLGPIRIPLLSDLNHQISKDYGVYLEDSGHTLRGLFIIDDKGVLRQITLNDLPVGRSVDE 230
           GLGP++IPLLSD+ H I+K YGVYL+D GH+LRGLFIID KG+LRQIT+NDLPVGRSVDE
Sbjct: 460 GLGPLKIPLLSDITHDIAKAYGVYLQDLGHSLRGLFIIDPKGILRQITMNDLPVGRSVDE 639

Query: 231 TLRLVQAFQYTDKHGEVCPAGWKPGSETIIPDPAGKLKYFDK 272
           TLRLVQAFQYTD HGEVCP GWKPGS+TIIPDP    KYF+K
Sbjct: 640 TLRLVQAFQYTDAHGEVCPVGWKPGSDTIIPDPKQSKKYFNK 765
>10721
          Length = 1542

 Score =  280 bits (717), Expect = 3e-76,   Method: Compositional matrix adjust.
 Identities = 128/197 (64%), Positives = 156/197 (79%)
 Frame = -2

Query: 78   HLSKAKISKPAPYWEGTAVINGEFKELKLTDYRGKYLVFFFYPLDFTFVCPTEIIAFGDR 137
             + +  I KPAP +   AV++G+FK +KL+DY+GKY+V FFYPLDFTFVCPTEIIAF DR
Sbjct: 1469 QIGQLAIQKPAPEFSVQAVVDGDFKTVKLSDYKGKYVVLFFYPLDFTFVCPTEIIAFSDR 1290

Query: 138  IEEFKSINTEVVACSVDSQFTHLAWINTPRRQGGLGPIRIPLLSDLNHQISKDYGVYLED 197
            +EEF+SI  EV+A S DS F+HLAW+NTPR+QGGLG ++IPLL+D   ++S+ YG   ED
Sbjct: 1289 VEEFRSIQCEVLAASTDSVFSHLAWVNTPRKQGGLGNMKIPLLADKTLELSRMYGCLKED 1110

Query: 198  SGHTLRGLFIIDDKGVLRQITLNDLPVGRSVDETLRLVQAFQYTDKHGEVCPAGWKPGSE 257
             G   R L+IIDDKG LRQIT+NDLPVGRSVDETLRLVQAFQ+TDKHGEVCPAGWKPG++
Sbjct: 1109 EGIAYRALYIIDDKGTLRQITMNDLPVGRSVDETLRLVQAFQFTDKHGEVCPAGWKPGAD 930

Query: 258  TIIPDPAGKLKYFDKLN 274
            TI P       +F K N
Sbjct: 929  TIKPSVKDSKTFFSKAN 879
>09123
          Length = 1944

 Score = 61.6 bits (148), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 41/159 (25%), Positives = 69/159 (43%), Gaps = 11/159 (6%)
 Frame = -3

Query: 113  YLVFFFYPLDFTFVCPTEIIAFGDRIEEFKSINTEVVACSVDSQFTHLAWINTPRRQGGL 172
            + + F +P D+T VC TE+    + I EF+    +V A S D   +H  W    ++  G+
Sbjct: 1606 WAILFSHPADYTPVCTTELGRVLNLIGEFEKRKCKVFALSCDGPESHKGWAKDVQKYAGV 1427

Query: 173  G---PIRIPLLSDLNHQISKDYGVYLEDSGH--------TLRGLFIIDDKGVLRQITLND 221
                    P+++D    ++   G+   D           T R +FII     L+   L  
Sbjct: 1426 DTDTKFPYPIIADEKRDLAVQLGMV--DPAEKTKDGLPLTCRAVFIIGPDKKLKLSLLYP 1253

Query: 222  LPVGRSVDETLRLVQAFQYTDKHGEVCPAGWKPGSETII 260
               GR+ DE LR++ + Q T       P  W+PG + ++
Sbjct: 1252 ATTGRNFDEILRVLDSLQLTATKKVATPENWQPGGKCMV 1136
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|114145493|ref|NP_062640.2| NS1-associated protein 1
isoform 1 [Mus musculus]
         (623 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

28652                                                                 360   e-100
31265                                                                 138   6e-33
11687                                                                  62   8e-10
17905                                                                  59   5e-09
03000                                                                  59   6e-09
17775                                                                  59   8e-09
39083                                                                  57   3e-08
21096                                                                  54   1e-07
03406                                                                  52   7e-07
23322                                                                  50   4e-06
17681                                                                  49   6e-06
25691                                                                  47   2e-05
16016                                                                  44   2e-05
08670                                                                  46   4e-05
31310                                                                  46   6e-05
12350                                                                  45   7e-05
02415                                                                  45   9e-05
31618                                                                  43   3e-04
30672                                                                  43   4e-04
00556                                                                  42   5e-04
08958                                                                  42   5e-04
16427                                                                  42   5e-04
19868                                                                  42   0.001
01278                                                                  41   0.001
00817                                                                  40   0.002
23250                                                                  40   0.003
11019                                                                  40   0.003
00029                                                                  39   0.005
04988                                                                  39   0.005
00302                                                                  39   0.005
23720                                                                  39   0.006
33516                                                                  39   0.006
02140                                                                  38   0.010
35180                                                                  37   0.018
25632                                                                  37   0.019
01937                                                                  37   0.021
32386                                                                  37   0.026
17175                                                                  36   0.036
12506                                                                  36   0.046
29364                                                                  35   0.064
24983                                                                  35   0.073
26197                                                                  35   0.077
30934                                                                  35   0.098
03903                                                                  34   0.14 
01065                                                                  33   0.30 
25950                                                                  33   0.33 
00738                                                                  33   0.34 
28605                                                                  32   0.67 
11126                                                                  31   1.7  
05273                                                                  30   2.1  
02809                                                                  30   2.1  
20169                                                                  30   2.9  
00781                                                                  30   3.1  
13457                                                                  28   7.7  
19556                                                                  28   8.7  
>28652
          Length = 918

 Score =  360 bits (925), Expect = e-100,   Method: Compositional matrix adjust.
 Identities = 176/310 (56%), Positives = 233/310 (75%), Gaps = 1/310 (0%)
 Frame = -2

Query: 95  LCGVMKTYRQREKQGTKVADSSKGPDEAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYS 154
           LCG MK  + +   G      +K PDEAKI+A+L+RTGY LDVTTGQRKYGGPPP   ++
Sbjct: 917 LCGKMKNLKTK---GAGGGAQTKKPDEAKIQAILKRTGYELDVTTGQRKYGGPPPG--WT 753

Query: 155 GQQPSVGTEIFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKE 214
             QP  G E+F GKIPRD+FEDEL+PLFE  G IWDLRLMMDP++ LNRGY FVT+ TKE
Sbjct: 752 DPQPGSGHEVFCGKIPRDIFEDELIPLFEDCGTIWDLRLMMDPVSNLNRGYCFVTYTTKE 573

Query: 215 AAQEAVKLYNNHEIRSGKHIGVCISVANNRLFVGSIPKSKTKEQILEEFSKVTEGLTDVI 274
           AA EAVK ++ +EIR GK + V IS+ N RLFVG+IPKSKTKE+IL+EF K +EGL DVI
Sbjct: 572 AAAEAVKQHDGYEIRKGKKLKVNISIPNLRLFVGNIPKSKTKEEILKEFEKHSEGLMDVI 393

Query: 275 LYHQPDDKK-KNRGFCFLEYEDHKTAAQARRRLMSGKVKVWGNVGTVEWADPIEDPDPEV 333
           +Y   D+ K KNRGF FLEY+ HK A+ A+RR  +G+ +VW     V+WAD  E+P+ E 
Sbjct: 392 VYGSADNPKLKNRGFAFLEYDTHKNASAAKRRFTTGRFRVWQCDVIVDWADLQEEPNEET 213

Query: 334 MAKVKVLFVRNLANTVTEEILEKSFSQFGKLERVKKLKDYAFIHFDERDGAVKAMEEMNG 393
           M+KVKVL+VRNL   VTE+ L++ F  +GK+ERVKK+KDY F+H+++R+ A+KA+++++G
Sbjct: 212 MSKVKVLYVRNLTGDVTEDDLKEKFGAYGKVERVKKIKDYGFVHYEDREDALKALDDLHG 33

Query: 394 KDLEGENIEI 403
           + +    I++
Sbjct: 32  EKIGNLEIDV 3
>31265
          Length = 540

 Score =  138 bits (348), Expect = 6e-33,   Method: Compositional matrix adjust.
 Identities = 62/129 (48%), Positives = 93/129 (72%), Gaps = 3/129 (2%)
 Frame = +2

Query: 286 RGFCFLEYEDHKTAAQARRRLMSGKVKVWGNVGTVEWADPIEDPDPEVMAKVKVLFVRNL 345
           RGF F+EY  H+ AA ARR+L+ G++++WG+   V+WA+P +D D + M++VK+L VRNL
Sbjct: 2   RGFAFVEYTSHRAAAMARRKLIPGRIQLWGHQIAVDWAEPEQDVDEDTMSQVKILXVRNL 181

Query: 346 ANTVTEEILEKSFSQFG---KLERVKKLKDYAFIHFDERDGAVKAMEEMNGKDLEGENIE 402
             T TEE L+  FS+     ++ERVKK++DYAF+HF  R+ A+KAM+  +G  +EG  +E
Sbjct: 182 MLTTTEETLKDVFSRAAGGREIERVKKIRDYAFVHFRSREDAIKAMDVTDGSTIEGSQVE 361

Query: 403 IVFAKPPDQ 411
           +V AKP D+
Sbjct: 362 VVLAKPVDK 388
>11687
          Length = 676

 Score = 62.0 bits (149), Expect = 8e-10,   Method: Compositional matrix adjust.
 Identities = 47/171 (27%), Positives = 82/171 (47%), Gaps = 16/171 (9%)
 Frame = +3

Query: 148 PPDSVYSGQQPSVGT-EIFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYA 206
           P   V S  +P   + ++FVG+IPR++ E+EL  +FE  GP+  L ++ D  TG ++G  
Sbjct: 105 PSTQVTSQGEPDADSIKMFVGQIPRNMDENELRKMFEDYGPVHSLNILRDKNTGQSKGCC 284

Query: 207 FVTFCTKEAAQEAVKLYNNHEIRSGKHIGVCISVANN------------RLFVGSIPKSK 254
           FVTF T++AA +A    +N +     H  V +  A++            +LFVG + K  
Sbjct: 285 FVTFFTRKAALDAQNALHNVKTMPMMHHPVQMKPADSEKRNGERNVEERKLFVGMLSKKL 464

Query: 255 TKEQI---LEEFSKVTEGLTDVILYHQPDDKKKNRGFCFLEYEDHKTAAQA 302
           ++  +    E F  + +     +L    D    +RG  F+ +   + A  +
Sbjct: 465 SENDVRMLFESFGSIDDC---TVLR---DSNGTSRGCAFITFASRQCAMNS 599

 Score = 45.1 bits (105), Expect = 8e-05,   Method: Compositional matrix adjust.
 Identities = 22/69 (31%), Positives = 41/69 (59%)
 Frame = +3

Query: 163 EIFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKL 222
           ++FVG + + L E+++  LFE  G I D  ++ D   G +RG AF+TF +++ A  ++K 
Sbjct: 432 KLFVGMLSKKLSENDVRMLFESFGSIDDCTVLRDS-NGTSRGCAFITFASRQCAMNSIKG 608

Query: 223 YNNHEIRSG 231
            ++ +   G
Sbjct: 609 MHHSQTMEG 635
>17905
          Length = 454

 Score = 59.3 bits (142), Expect = 5e-09,   Method: Compositional matrix adjust.
 Identities = 29/49 (59%), Positives = 39/49 (79%)
 Frame = -1

Query: 24  SENFQTLLDAGLPQKVAEKLDEIYVAGLVAHSDLDERAIEALKEFNEDG 72
           +E++  LL+ GL +KVA KLDEIY  G +AH++LDERA++ALKEF  DG
Sbjct: 148 TEDYPKLLEYGLDKKVAGKLDEIYKTGKLAHAELDERALDALKEFPVDG 2
>03000
          Length = 778

 Score = 58.9 bits (141), Expect = 6e-09,   Method: Compositional matrix adjust.
 Identities = 44/162 (27%), Positives = 80/162 (49%), Gaps = 15/162 (9%)
 Frame = +3

Query: 164 IFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLY 223
           +F+G +  +  ED L   FE  G I D  +M D  +  +RG+ F+T+   E+  +A +  
Sbjct: 93  LFIGGLSYETDEDSLRSHFETWGEIVDCIVMRDSNSKRSRGFGFITYKDAESIDQA-QAN 269

Query: 224 NNHEIRSGKHIGVC------------ISVANNRLFVGSIPKSKTKEQILEEFSKVTEGLT 271
             H+I  G+ +               +  +  ++FVG + +  T++ I + F++  E +T
Sbjct: 270 RPHKI-DGREVDTKRAMPREESGRSEVQQSVKKMFVGGVKEDTTEDMIRDTFNEFGE-IT 443

Query: 272 DVILYHQPDDKKKNRGFCFLEYEDHKTAAQA---RRRLMSGK 310
            V L  Q     KNRGFCF+ + DH +  +A   +R  ++G+
Sbjct: 444 GVDLI-QDKGTGKNRGFCFVTFGDHDSVDKAVLKKRHDLNGR 566

 Score = 51.6 bits (122), Expect = 8e-07,   Method: Compositional matrix adjust.
 Identities = 43/169 (25%), Positives = 82/169 (48%), Gaps = 9/169 (5%)
 Frame = +3

Query: 244 RLFVGSIPKSKTKEQILEEFSKVTEGLTDVILYHQPDDKKKNRGFCFLEYEDHKTAAQAR 303
           +LF+G +     ++ +   F    E + D I+    +  K++RGF F+ Y+D ++  QA+
Sbjct: 90  KLFIGGLSYETDEDSLRSHFETWGE-IVDCIVMRDSN-SKRSRGFGFITYKDAESIDQAQ 263

Query: 304 RRLMSGKVKVWGNVGTVEWADPIEDPD-PEVMAKVKVLFVRNLANTVTEEILEKSFSQFG 362
               +   K+ G     + A P E+    EV   VK +FV  +    TE+++  +F++FG
Sbjct: 264 ---ANRPHKIDGREVDTKRAMPREESGRSEVQQSVKKMFVGGVKEDTTEDMIRDTFNEFG 434

Query: 363 KLERVKKLKD--------YAFIHFDERDGAVKAMEEMNGKDLEGENIEI 403
           ++  V  ++D        + F+ F + D   KA+ +    DL G  +E+
Sbjct: 435 EITGVDLIQDKGTGKNRGFCFVTFGDHDSVDKAVLKKR-HDLNGRQVEV 578

 Score = 48.5 bits (114), Expect = 9e-06,   Method: Compositional matrix adjust.
 Identities = 32/90 (35%), Positives = 49/90 (54%)
 Frame = +3

Query: 147 PPPDSVYSGQQPSVGTEIFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYA 206
           P  +S  S  Q SV  ++FVG +  D  ED +   F + G I  + L+ D  TG NRG+ 
Sbjct: 318 PREESGRSEVQQSV-KKMFVGGVKEDTTEDMIRDTFNEFGEITGVDLIQDKGTGKNRGFC 494

Query: 207 FVTFCTKEAAQEAVKLYNNHEIRSGKHIGV 236
           FVTF   ++  +AV L   H++ +G+ + V
Sbjct: 495 FVTFGDHDSVDKAV-LKKRHDL-NGRQVEV 578
>17775
          Length = 1282

 Score = 58.5 bits (140), Expect = 8e-09,   Method: Compositional matrix adjust.
 Identities = 73/307 (23%), Positives = 134/307 (43%), Gaps = 33/307 (10%)
 Frame = -2

Query: 146 GPPPDSVYSGQQPSVGTE----IFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGL 201
           G P   ++S + PSV       +F+  + + +    L   F   G I   ++  D     
Sbjct: 990 GRPIRIMWSQRDPSVRKSGVGNVFIKNLDKTIDNKALYDTFSAFGNILSCKIACDEQG-- 817

Query: 202 NRGYAFVTFCTKEAAQEAVKLYNNHEIRSGK-HIGVCISVANNRLFVGSIPKSKTKEQIL 260
           ++GY FV F T+EAA++A+   N   +   K ++G  I      + +G   K +     +
Sbjct: 816 SKGYGFVHFETEEAARQAIDKVNGMLLNGKKVYVGRFIPRKERIMMMGDKLK-RFNNVYV 640

Query: 261 EEFSKVTEGLTDVILYHQP-----------DDKKKNRGFCFLEYEDHKTAAQARRRL--- 306
           + F   T       L  Q             +  K+RGF F+ +E+ + A +A   +   
Sbjct: 639 KNFC*GTG*RPAA*LVWQARQDHLXXGACRGEDGKSRGFGFVSFEEPEGAEKAVDEINGT 460

Query: 307 -MSGKVKVWGNVGT-----VEWADPIEDPDPEVMAKVK--VLFVRNLANTVTEEILEKSF 358
            +SG++   G          E  +  E    E + + +   L+V+NL +++ +E L K F
Sbjct: 459 EVSGRIIYCGRAQKRAERQAELKERFEKIKLERINRYQGVNLYVKNLDDSIDDERLRKEF 280

Query: 359 SQFGKLERVKKL------KDYAFIHFDERDGAVKAMEEMNGKDLEGENIEIVFAKPPDQK 412
           S FG +   K +      K + F+ F   + A KA+ EMNG+ +  + + +  A    Q+
Sbjct: 279 SNFGTITSAKIMTEGGRSKGFGFVCFSSPEEATKAVTEMNGRIIVAKPLYVALA----QR 112

Query: 413 RKERKAQ 419
           +++R+AQ
Sbjct: 111 KEDRRAQ 91

 Score = 56.2 bits (134), Expect = 4e-08,   Method: Compositional matrix adjust.
 Identities = 68/280 (24%), Positives = 126/280 (45%), Gaps = 23/280 (8%)
 Frame = -2

Query: 163  EIFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKL 222
             ++VG +  D+ E  L   F  AGP+  +R+  D +T  + GYA+V F     A+ A+  
Sbjct: 1191 SLYVGDLHPDVTEAMLFEKFSTAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDT 1012

Query: 223  YNNHEIRSGKHIGVCIS----------VANNRLFVGSIPKSKTKEQILEEFSKVTEGLTD 272
             N   ++ G+ I +  S          V N  +F+ ++ K+   + + + FS     L+ 
Sbjct: 1011 MNFDTVK-GRPIRIMWSQRDPSVRKSGVGN--VFIKNLDKTIDNKALYDTFSAFGNILSC 841

Query: 273  VILYHQPDDKKKNRGFCFLEYEDHKTAAQARRR----LMSG-KVKVWGNVGTVEWADPIE 327
             I      D++ ++G+ F+ +E  + A QA  +    L++G KV V   +   E    + 
Sbjct: 840  KIAC----DEQGSKGYGFVHFETEEAARQAIDKVNGMLLNGKKVYVGRFIPRKERIMMMG 673

Query: 328  DPDPEVMAKVKVLFVRNL--------ANTVTEEILEKSFSQFGKLERVKKLKDYAFIHFD 379
            D     + +   ++V+N         A  +  +  +             K + + F+ F+
Sbjct: 672  DK----LKRFNNVYVKNFC*GTG*RPAA*LVWQARQDHLXXGACRGEDGKSRGFGFVSFE 505

Query: 380  ERDGAVKAMEEMNGKDLEGENIEIVFAKPPDQKRKERKAQ 419
            E +GA KA++E+NG ++ G  I    A    QKR ER+A+
Sbjct: 504  EPEGAEKAVDEINGTEVSGRIIYCGRA----QKRAERQAE 397
>39083
          Length = 1400

 Score = 56.6 bits (135), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 32/61 (52%), Positives = 40/61 (65%), Gaps = 2/61 (3%)
 Frame = -3

Query: 564  KRKADG-YNQPDTKRRQTNNQNWGSQPIAQQPL-QGGDHSGNYGYKSENQEFYQDTFGQQ 621
            KRKA   ++Q  TKR  T   NWG++PIAQQPL Q G  SG Y Y   + ++YQD+FGQ 
Sbjct: 1200 KRKAGSDFSQGVTKRPYTRAGNWGNEPIAQQPLDQSGYGSGGYDYSGNDAQWYQDSFGQN 1021

Query: 622  W 622
            W
Sbjct: 1020 W 1018
>21096
          Length = 1186

 Score = 54.3 bits (129), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 30/100 (30%), Positives = 56/100 (56%), Gaps = 2/100 (2%)
 Frame = +3

Query: 314 WGNVGTVEWADPIEDPDPEVMAKVKVLFVRNLANTVTEEILEKSFSQFGKLERVKKL--K 371
           + N+  +    P+ + D  V   VK LFV     +V E +L  +FS+FG L  V  L  +
Sbjct: 12  YCNIA-LPLTQPLVNDDSTV---VKRLFVVCQPGSVPERVLRDAFSRFGNLISVYLLSGR 179

Query: 372 DYAFIHFDERDGAVKAMEEMNGKDLEGENIEIVFAKPPDQ 411
           +Y +  +   + A+KA++ ++G+ L G+ ++++ A+PP Q
Sbjct: 180 NYGYAKYANHESAMKALQTLHGQSLSGQRLKVLEAEPPKQ 299
>03406
          Length = 1292

 Score = 52.0 bits (123), Expect = 7e-07,   Method: Compositional matrix adjust.
 Identities = 45/147 (30%), Positives = 66/147 (44%), Gaps = 7/147 (4%)
 Frame = +3

Query: 163 EIFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKL 222
           +IFVG +  +     L   FEK G +    L  D  +G +RG+ FV F  KEAA     +
Sbjct: 243 KIFVGGLSWETXSKHLREYFEKFGEVTSCTLKTDLDSGKSRGFGFVVF--KEAATVDAVV 416

Query: 223 YNNHEIRSGKHIGVCISVANNR-----LFVGSIPKSKTKEQILEEFSKVTEGLTDVILYH 277
            N      G+ I      AN R     +FVG +     +E +   F+K       V+   
Sbjct: 417 KNKEHKLQGRKIDP--KPANPRKGMRKIFVGKLDPGVPQEDVESYFAK----FGKVVNVE 578

Query: 278 QPDDKKKN--RGFCFLEYEDHKTAAQA 302
            P DK K+  R FCF+E+++ KT  + 
Sbjct: 579 LPYDKVKDQRRAFCFVEFDNDKTVKKV 659
>23322
          Length = 471

 Score = 49.7 bits (117), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 33/99 (33%), Positives = 53/99 (53%)
 Frame = -2

Query: 147 PPPDSVYSGQQPSVGTEIFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYA 206
           P  +S  S  Q SV  ++FVG +  D  ED +   F + G I  + L+ D  TG NRG+ 
Sbjct: 452 PREESGRSEVQQSV-KKMFVGGVKEDTTEDMIRDTFNEFGEITGVDLIQDKGTGKNRGFC 276

Query: 207 FVTFCTKEAAQEAVKLYNNHEIRSGKHIGVCISVANNRL 245
           FVTF   ++  +AV L   H++ +G+ + V  + + N +
Sbjct: 275 FVTFGDHDSVDKAV-LKKRHDL-NGRQVEVKKAQSKNDM 165

 Score = 40.0 bits (92), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 21/59 (35%), Positives = 35/59 (59%)
 Frame = -2

Query: 244 RLFVGSIPKSKTKEQILEEFSKVTEGLTDVILYHQPDDKKKNRGFCFLEYEDHKTAAQA 302
           ++FVG + +  T++ I + F++  E +T V L  Q     KNRGFCF+ + DH +  +A
Sbjct: 407 KMFVGGVKEDTTEDMIRDTFNEFGE-ITGVDLI-QDKGTGKNRGFCFVTFGDHDSVDKA 237
>17681
          Length = 964

 Score = 48.9 bits (115), Expect = 6e-06,   Method: Compositional matrix adjust.
 Identities = 29/86 (33%), Positives = 48/86 (55%), Gaps = 1/86 (1%)
 Frame = +2

Query: 150 DSVYSGQQPSVGTEIFVGKIPRDLFEDELV-PLFEKAGPIWDLRLMMDPLTGLNRGYAFV 208
           + VY+   P+  T ++ G  P ++  DEL+   F + GPI D+R+  D      +G+AF+
Sbjct: 389 EEVYNQSSPT-NTTVYCGGFPPNVISDELMHKHFMQFGPIQDVRVFKD------KGFAFI 547

Query: 209 TFCTKEAAQEAVKLYNNHEIRSGKHI 234
            F TKEAA  A++  +  E+  G H+
Sbjct: 548 KFVTKEAAARAIEHTHISEVH-GNHV 622

 Score = 44.7 bits (104), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 24/68 (35%), Positives = 37/68 (54%)
 Frame = +2

Query: 163 EIFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKL 222
            IFVG +  ++  + L   F   G I + R++ DP T  ++GYAFV+F  K  A+ A++ 
Sbjct: 35  HIFVGDLSPEIETETLREAFAPFGEISNCRIVRDPQTMKSKGYAFVSFVKKAEAENAIQA 214

Query: 223 YNNHEIRS 230
            N   I S
Sbjct: 215 MNGQWIGS 238

 Score = 37.7 bits (86), Expect = 0.014,   Method: Compositional matrix adjust.
 Identities = 22/87 (25%), Positives = 45/87 (51%), Gaps = 12/87 (13%)
 Frame = +2

Query: 340 LFVRNLANTVTEEILEKSFSQFGKLERVKKLKD--------YAFIHFDERDGAVKAMEEM 391
           +FV +L+  +  E L ++F+ FG++   + ++D        YAF+ F ++  A  A++ M
Sbjct: 38  IFVGDLSPEIETETLREAFAPFGEISNCRIVRDPQTMKSKGYAFVSFVKKAEAENAIQAM 217

Query: 392 NGKDLEGENIEIVFAK----PPDQKRK 414
           NG+ +   +I   ++     PP +  K
Sbjct: 218 NGQWIGSRSIRTNWSTRKLPPPRESSK 298
>25691
          Length = 768

 Score = 47.4 bits (111), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 21/66 (31%), Positives = 37/66 (56%)
 Frame = -2

Query: 161 GTEIFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAV 220
           G  +++  +P+ L + +L  LF   G I   R++ D  TGL++G  F+ F  +  A+ A+
Sbjct: 263 GANLYISGLPKSLTQLDLENLFTDCGNIITSRILYDQTTGLSKGVGFIRFDQRIEAERAI 84

Query: 221 KLYNNH 226
           +  NNH
Sbjct: 83  QKLNNH 66

 Score = 42.4 bits (98), Expect = 6e-04,   Method: Compositional matrix adjust.
 Identities = 30/103 (29%), Positives = 46/103 (44%), Gaps = 5/103 (4%)
 Frame = -2

Query: 191 LRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLYN-----NHEIRSGKHIGVCISVANNRL 245
            +L+ D  TG + GY FV +  +E A +A+   N     N  I+       C S+    L
Sbjct: 431 CKLIRDKPTGQSLGYGFVNYKRQEDADKAIHTLNGLRLQNKTIKVSLARPSCESIKGANL 252

Query: 246 FVGSIPKSKTKEQILEEFSKVTEGLTDVILYHQPDDKKKNRGF 288
           ++  +PKS T+  +   F+     +T  ILY Q     K  GF
Sbjct: 251 YISGLPKSLTQLDLENLFTDCGNIITSRILYDQTTGLSKGVGF 123

 Score = 31.2 bits (69), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 11/36 (30%), Positives = 23/36 (63%)
 Frame = -2

Query: 373 YAFIHFDERDGAVKAMEEMNGKDLEGENIEIVFAKP 408
           Y F+++  ++ A KA+  +NG  L+ + I++  A+P
Sbjct: 389 YGFVNYKRQEDADKAIHTLNGLRLQNKTIKVSLARP 282
>16016
          Length = 1364

 Score = 43.9 bits (102), Expect(2) = 2e-05,   Method: Compositional matrix adjust.
 Identities = 33/115 (28%), Positives = 56/115 (48%), Gaps = 10/115 (8%)
 Frame = -2

Query: 164  IFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLY 223
            +F+G +  D  E  L   FEK G I +  ++ DP T  +R ++F+TF   E   E V+  
Sbjct: 1303 VFIGGMHPDTDESSLRSYFEKYGDIRECIVVKDPATKRSRCFSFITFGNAENVDE-VQKD 1127

Query: 224  NNHEIRSGKHIGVCISVA---------NNRLFVGSIPKSKTKEQILEEFS-KVTE 268
              H I  G+ +    ++            ++FVG +    T+E + +EF+ K+TE
Sbjct: 1126 RPHTI-DGRTVETKRAMPREDTENHHQTKKMFVGGLKDDTTEEMLRKEFTGKITE 965

 Score = 22.7 bits (47), Expect(2) = 2e-05,   Method: Compositional matrix adjust.
 Identities = 7/13 (53%), Positives = 10/13 (76%)
 Frame = -1

Query: 286 RGFCFLEYEDHKT 298
           RGFCF+ ++D  T
Sbjct: 929 RGFCFVSFDDCDT 891

 Score = 32.0 bits (71), Expect = 0.77,   Method: Compositional matrix adjust.
 Identities = 30/121 (24%), Positives = 53/121 (43%), Gaps = 3/121 (2%)
 Frame = -2

Query: 242  NNRLFVGSIPKSKTKEQILEEFSKVTEGLTDVILYHQPDDKKKNRGFCFLEY---EDHKT 298
            N ++F+G +    T E  L  + +    + + I+   P   K++R F F+ +   E+   
Sbjct: 1312 NRKVFIGGM-HPDTDESSLRSYFEKYGDIRECIVVKDPA-TKRSRCFSFITFGNAENVDE 1139

Query: 299  AAQARRRLMSGKVKVWGNVGTVEWADPIEDPDPEVMAKVKVLFVRNLANTVTEEILEKSF 358
              + R   + G+        TVE    +   D E   + K +FV  L +  TEE+L K F
Sbjct: 1138 VQKDRPHTIDGR--------TVETKRAMPREDTENHHQTKKMFVGGLKDDTTEEMLRKEF 983

Query: 359  S 359
            +
Sbjct: 982  T 980
>08670
          Length = 1307

 Score = 45.8 bits (107), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 37/134 (27%), Positives = 64/134 (47%), Gaps = 21/134 (15%)
 Frame = +2

Query: 293 YEDHKTAAQARRRLMSGKV--KVWGNVGTVEWAD-------PIEDP----------DPEV 333
           Y+ H T   A   L+SG V   + G V   +  D       P+  P          DP+ 
Sbjct: 761 YKKHSTVPAALEALLSGTVDESLAGEVYLSDEEDYVAPKSIPVPQPLASMPADSKMDPKN 940

Query: 334 MAKVKVLFVRNLANTVTEEILEKSFSQFGKLERVKKL--KDYAFIHFDERDGAVKAMEEM 391
              +  L+V N+   VTE+ L + F++ G +  V+ L  K  AFI++  ++ A +AM+ +
Sbjct: 941 PEGLTALWVGNVLPQVTEKRLTQMFAKHGPVASVRMLPEKYCAFINYKLKESAGRAMQYL 1120

Query: 392 NGKDLEGENIEIVF 405
             ++ EG+++ I F
Sbjct: 1121QNQECEGQHLLIRF 1162
>31310
          Length = 469

 Score = 45.8 bits (107), Expect = 6e-05,   Method: Compositional matrix adjust.
 Identities = 28/87 (32%), Positives = 48/87 (55%)
 Frame = -3

Query: 150 DSVYSGQQPSVGTEIFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVT 209
           ++V   Q  ++   I+VG I  ++ ED +   F   GPI  + L  DP+T  ++G++F+ 
Sbjct: 359 NTVQRQQALALMCRIYVGSINFEIREDTIKQAFLPFGPIKSVNLSWDPITNKHKGFSFIE 180

Query: 210 FCTKEAAQEAVKLYNNHEIRSGKHIGV 236
           +   EAAQ A++  N   I  G++I V
Sbjct: 179 YDVPEAAQLALEQMNGVMI-GGRNIKV 102
>12350
          Length = 975

 Score = 45.4 bits (106), Expect = 7e-05,   Method: Compositional matrix adjust.
 Identities = 40/161 (24%), Positives = 69/161 (42%), Gaps = 8/161 (4%)
 Frame = -2

Query: 147 PPPDSVYSGQQPSVGTEIFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYA 206
           P P  V S  +      I +G +P    ED+L   F + G +  +++  DP TG ++G+ 
Sbjct: 662 PGPKVVKSSSRQKCSDLIVLG-LPWKSTEDDLRSYFSQFGDLLMVQVKKDPKTGQSKGFG 486

Query: 207 FVTFCTKEAAQEAVKLYNNHEIRSGKHIGVCI--------SVANNRLFVGSIPKSKTKEQ 258
           F+ F   E+    +K      +  G+   V I         + N ++FVG      T + 
Sbjct: 485 FIRFAEYESQ---LKCMAQRHMIDGRWCDVRIPNSKEGAQQLMNRKIFVGRCTDDMTADD 315

Query: 259 ILEEFSKVTEGLTDVILYHQPDDKKKNRGFCFLEYEDHKTA 299
           + + FSK  E + DV +       +  R F F+ + D + A
Sbjct: 314 LRQFFSKFGE-VVDVFI------PRPFRAFAFVSFADPEVA 213
>02415
          Length = 2763

 Score = 45.1 bits (105), Expect = 9e-05,   Method: Compositional matrix adjust.
 Identities = 31/99 (31%), Positives = 50/99 (50%)
 Frame = -1

Query: 154  SGQQPSVGTEIFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTK 213
            +GQ+ +  T+IFVG +P    +  L   F+K G I +  ++ D  TG +RGY FVT   +
Sbjct: 1950 TGQKDTTYTKIFVGGLPYHTTDHSLREYFDKFGDIDEAVVITDRQTGKSRGYGFVTMADR 1771

Query: 214  EAAQEAVKLYNNHEIRSGKHIGVCISVANNRLFVGSIPK 252
              A  A K  + + I  G+   V      N  ++G+ P+
Sbjct: 1770 TGADRACK--DPNPIIDGRKANV------NLAYIGAKPR 1678
>31618
          Length = 716

 Score = 43.1 bits (100), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 39/141 (27%), Positives = 63/141 (44%), Gaps = 3/141 (2%)
 Frame = +1

Query: 163 EIFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKL 222
           ++FVG +  +  E EL   F K G I  + +  DP TG +RG+AF+ F   EA  + V  
Sbjct: 295 KLFVGGLSWETTEKELRDHFGKYGEIESINVKTDPQTGRSRGFAFIVFTNTEAIDQ-VSA 471

Query: 223 YNNHEIRSGKHIGVCISVANNRLFVGSIPKSKTKEQILEEFSKVTE-GLTDVILYHQPDD 281
              H I S K           RL +         +++    SK T   L +++    P D
Sbjct: 472 AEEHIINSKK----VDPKKKPRLAMARFLSVA*PQRLAMRKSKPTSVNLDNIVEVEMPFD 639

Query: 282 KKKN--RGFCFLEYEDHKTAA 300
           K+K+  +GF F+ ++  +   
Sbjct: 640 KQKSHRKGFXFITFDSEQVVT 702
>30672
          Length = 877

 Score = 42.7 bits (99), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 49/212 (23%), Positives = 87/212 (41%), Gaps = 45/212 (21%)
 Frame = +3

Query: 245 LFVGSIPKSKTKEQILEEFSKVTEGLTDVILYHQPDDKKKNRGFCFLEYEDHKTAAQARR 304
           LFV ++P   + E++LE F +V    T  ++  +  +  K RGF ++++   + A +A+ 
Sbjct: 18  LFVRNLPFETSNEKLLEAFEQVGPLKTAFVVAGK--EPGKCRGFGYVQFSMLEDAIKAKD 191

Query: 305 RL--MSGKV---------KVWGNV--GTVEWADPI----------------EDPDPEV-- 333
            +   SG+          K W     G  E +D +                 +P PE   
Sbjct: 192 TVTHCSGRKISLSFADTKKSWKTKQKGGTETSDALGLGKKLPSQTAVTDGEPNPKPEKKK 371

Query: 334 -------MAKVKVLFVRNLANTVTEEILEKSFSQFGKLERVK-------KLKDYAFIHFD 379
                  + K   L +RNLA    E  +   F +FG +  V        + + +AF+ F 
Sbjct: 372 TKQPKQELGKRCRLIIRNLAFKCKEADIRSHFGKFGTISEVTIPLKQGDRSRGFAFVQFT 551

Query: 380 ERDGAVKAMEEMNGKDLEGENIEIVFAKPPDQ 411
           E   A KA+ +MNG  +    + + +A   D+
Sbjct: 552 EVKAAQKAISDMNGTAIMDRPVAVDWAVAKDR 647

 Score = 33.5 bits (75), Expect = 0.23,   Method: Compositional matrix adjust.
 Identities = 22/77 (28%), Positives = 35/77 (45%), Gaps = 8/77 (10%)
 Frame = +3

Query: 338 KVLFVRNLANTVTEEILEKSFSQFGKLERV--------KKLKDYAFIHFDERDGAVKAME 389
           K LFVRNL    + E L ++F Q G L+           K + + ++ F   + A+KA +
Sbjct: 12  KTLFVRNLPFETSNEKLLEAFEQVGPLKTAFVVAGKEPGKCRGFGYVQFSMLEDAIKAKD 191

Query: 390 EMNGKDLEGENIEIVFA 406
            +      G  I + FA
Sbjct: 192 TVT--HCSGRKISLSFA 236

 Score = 31.6 bits (70), Expect = 0.91,   Method: Compositional matrix adjust.
 Identities = 19/76 (25%), Positives = 37/76 (48%)
 Frame = +3

Query: 164 IFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLY 223
           +FV  +P +   ++L+  FE+ GP+    ++     G  RG+ +V F   E   +A+K  
Sbjct: 18  LFVRNLPFETSNEKLLEAFEQVGPLKTAFVVAGKEPGKCRGFGYVQFSMLE---DAIKAK 188

Query: 224 NNHEIRSGKHIGVCIS 239
           +     SG+ I +  +
Sbjct: 189 DTVTHCSGRKISLSFA 236

 Score = 28.5 bits (62), Expect = 7.5,   Method: Compositional matrix adjust.
 Identities = 16/44 (36%), Positives = 25/44 (56%)
 Frame = +3

Query: 202 NRGYAFVTFCTKEAAQEAVKLYNNHEIRSGKHIGVCISVANNRL 245
           +RG+AFV F   +AAQ+A+   N   I   + + V  +VA +R 
Sbjct: 522 SRGFAFVQFTEVKAAQKAISDMNGTAIMD-RPVAVDWAVAKDRF 650
>00556
          Length = 2189

 Score = 42.4 bits (98), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 22/72 (30%), Positives = 36/72 (50%)
 Frame = +3

Query: 163 EIFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKL 222
           +IF+G +P  L ED++  L    GP+    L+ D  TGL++G+AF  +       +A   
Sbjct: 762 KIFMGGLPSYLSEDQMKELLLSFGPLKSFNLVRDNATGLSKGFAFCEYLDPSVTDQACAG 941

Query: 223 YNNHEIRSGKHI 234
            N  ++   K I
Sbjct: 942 LNGMQLGDKKLI 977
>08958
          Length = 680

 Score = 42.4 bits (98), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 51/200 (25%), Positives = 88/200 (44%), Gaps = 11/200 (5%)
 Frame = +2

Query: 227 EIRSGKHIGVCISVANNRLFVGSIPKSKTKE---QILEEFSKVTEGLTDVILYHQPDDKK 283
           E R  K  G C      RLFVG++    +++   ++   F +V+E   +           
Sbjct: 38  EYRRKKFTGRC------RLFVGNLTPDVSEDDFKKLFSPFGEVSEAYVN----------- 166

Query: 284 KNRGFCFLEYEDHKTAAQARRRLMSGKVKVWGNVGTVEWADPIEDPDPEVMAKVKVLFVR 343
             RGF F+   D++  A+A +  + G ++  G    V +A                L V+
Sbjct: 167 SGRGFGFIRL-DYRHNAEAAKAALDG-LQRKGRSLRVRYA-----------THGAALKVK 307

Query: 344 NLANTVTEEILEKSFSQFGKLERVKKLKD-------YAFIHFDERDGAVKAMEEMN-GKD 395
           NL   V+ E+LE++F+QFG LER   + D          + F  + GA +A+  +N G  
Sbjct: 308 NLHPYVSNELLEQAFTQFGDLERAIVIVDERGRSTGEGVVEFVRKPGAQQALRRINEGVF 487

Query: 396 LEGENIEIVFAKPPDQKRKE 415
           L G + + +  +P + K +E
Sbjct: 488 LFGADPKPIEVEPLEHKDEE 547

 Score = 33.1 bits (74), Expect = 0.35,   Method: Compositional matrix adjust.
 Identities = 37/169 (21%), Positives = 72/169 (42%)
 Frame = +2

Query: 164 IFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLY 223
           +FVG +  D+ ED+   LF   G +       +      RG+ F+    +  A EA K  
Sbjct: 74  LFVGNLTPDVSEDDFKKLFSPFGEV------SEAYVNSGRGFGFIRLDYRHNA-EAAKAA 232

Query: 224 NNHEIRSGKHIGVCISVANNRLFVGSIPKSKTKEQILEEFSKVTEGLTDVILYHQPDDKK 283
            +   R G+ + V  +     L V ++    + E + + F++  +    +++    D++ 
Sbjct: 233 LDGLQRKGRSLRVRYATHGAALKVKNLHPYVSNELLEQAFTQFGDLERAIVIV---DERG 403

Query: 284 KNRGFCFLEYEDHKTAAQARRRLMSGKVKVWGNVGTVEWADPIEDPDPE 332
           ++ G   +E+     A QA RR+  G      +   +E  +P+E  D E
Sbjct: 404 RSTGEGVVEFVRKPGAQQALRRINEGVFLFGADPKPIE-VEPLEHKDEE 547
>16427
          Length = 1313

 Score = 42.4 bits (98), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 20/72 (27%), Positives = 42/72 (58%), Gaps = 8/72 (11%)
 Frame = +1

Query: 340 LFVRNLANTVTEEILEKSFSQFGKLERVKKLKD--------YAFIHFDERDGAVKAMEEM 391
           LFV  LA  + E++LE+ FS+FG++     ++D        + F+ ++    A +A++ M
Sbjct: 142 LFVGGLAEEIDEKVLEREFSKFGRITESMVIRDKVRQVSRGFGFVTYENPMDAEEAVKHM 321

Query: 392 NGKDLEGENIEI 403
           +GK++ G+ + +
Sbjct: 322 DGKEILGKKLHV 357

 Score = 36.6 bits (83), Expect = 0.033,   Method: Compositional matrix adjust.
 Identities = 22/66 (33%), Positives = 37/66 (56%)
 Frame = +1

Query: 163 EIFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKL 222
           ++FVG +  ++ E  L   F K G I +  ++ D +  ++RG+ FVT+     A+EAVK 
Sbjct: 139 KLFVGGLAEEIDEKVLEREFSKFGRITESMVIRDKVRQVSRGFGFVTYENPMDAEEAVKH 318

Query: 223 YNNHEI 228
            +  EI
Sbjct: 319 MDGKEI 336
>19868
          Length = 434

 Score = 41.6 bits (96), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 34/147 (23%), Positives = 65/147 (44%), Gaps = 13/147 (8%)
 Frame = +2

Query: 163 EIFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKL 222
           ++FVG +      + L   F K G I ++ +M DP T  +RG+ F+TF    A+ + V  
Sbjct: 2   KMFVGGLSWQTSPESLRDYFNKFGEITEVMVMKDPTTRRSRGFGFITFG-DPASVDKVLA 178

Query: 223 YNNHEIRSGKHIGVCISVA----------NNRLFVGSIPKSKTKEQI---LEEFSKVTEG 269
              HE+  GK I   ++              ++FVG +    T E +    E+F  + + 
Sbjct: 179 QATHEL-DGKKIDPKVAFPRRAHPRMVTRTKKIFVGGLSAPTTLEDVKNYFEQFGPIEDA 355

Query: 270 LTDVILYHQPDDKKKNRGFCFLEYEDH 296
           +   +++ +  ++ +  GF  +    H
Sbjct: 356 M---LMFDKQTNRHRGFGFVTISKRRH 427
>01278
          Length = 1082

 Score = 41.2 bits (95), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 21/57 (36%), Positives = 31/57 (54%)
 Frame = +2

Query: 164 IFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAV 220
           I V  +  D  E +L  LF   GPI  + L  D +TG ++G+AF+ F  +E A  A+
Sbjct: 641 IRVTNLSEDTRESDLQELFRPFGPISRIYLAKDKVTGQSKGFAFINFHRREDASRAI 811

 Score = 36.6 bits (83), Expect = 0.032,   Method: Compositional matrix adjust.
 Identities = 23/82 (28%), Positives = 41/82 (50%), Gaps = 8/82 (9%)
 Frame = +2

Query: 339 VLFVRNLANTVTEEILEKSFSQFGKLERVKKLKD--------YAFIHFDERDGAVKAMEE 390
            + V NL+    E  L++ F  FG + R+   KD        +AFI+F  R+ A +A+  
Sbjct: 638 TIRVTNLSEDTRESDLQELFRPFGPISRIYLAKDKVTGQSKGFAFINFHRREDASRAIAG 817

Query: 391 MNGKDLEGENIEIVFAKPPDQK 412
           ++G   +   + + +AKP  Q+
Sbjct: 818 VSGFGYDHLILNVEWAKPSGQQ 883
>00817
          Length = 2606

 Score = 40.4 bits (93), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 20/58 (34%), Positives = 30/58 (51%)
 Frame = -2

Query: 164  IFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVK 221
            +F+G +  D  E  L   FEK G I +  ++ DP T  +R ++F+TF   E   E  K
Sbjct: 2545 VFIGGMHPDTDESSLRSYFEKYGDIRECIVVKDPATKRSRCFSFITFGNAENVDEVQK 2372
>23250
          Length = 1617

 Score = 40.0 bits (92), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 18/54 (33%), Positives = 30/54 (55%)
 Frame = -1

Query: 164  IFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQ 217
            +++G IP   +E ++   F + G +  LRL     TG ++GYAF+ F T+   Q
Sbjct: 1329 VYLGHIPAGFYEPQMKRFFSQFGRVTRLRLSRSTKTGGSKGYAFLEF*TRGCGQ 1168
>11019
          Length = 552

 Score = 39.7 bits (91), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 22/68 (32%), Positives = 37/68 (54%)
 Frame = -1

Query: 163 EIFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKL 222
           +IFVG +      +++   F+  G I +  LM D +T  +RG+AFVTF  +    +  ++
Sbjct: 231 KIFVGGLSSSTTVEDIKNYFKAYGTIEEATLMFDKVTSRHRGFAFVTFDNESTVDKVCEI 52

Query: 223 YNNHEIRS 230
           +  HEI S
Sbjct: 51  H-FHEINS 31

 Score = 38.5 bits (88), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 41/181 (22%), Positives = 73/181 (40%), Gaps = 30/181 (16%)
 Frame = -1

Query: 247 VGSIPKSKTKEQILEEFSKVTEGLTDVILYHQPDDKKKNRGFCFLEYEDHKT-------- 298
           +G +    T E +   F K  E + + ++   P  K+ +RGF F+ Y+D           
Sbjct: 552 IGGLSWQTTTETLRSYFEKFGE-IKESMVMKDPTSKR-SRGFGFVTYKDPSNVDNVLANG 379

Query: 299 --AAQARRRLMSGKVKVWGNVGTVEWADPIEDP--------DPEVMAKVKVLFVRNLANT 348
                ++    S     + N   + +  P  DP        +P ++ K K +FV  L+++
Sbjct: 378 PHCIDSKTLNFSNMTTFYSNQDLLPYP-PQVDPKVAFPRKSNPRMVTKTKKIFVGGLSSS 202

Query: 349 VTEEILEKSFSQFGKLERVKKLKD--------YAFIHFDERDGAVKAME----EMNGKDL 396
            T E ++  F  +G +E    + D        +AF+ FD      K  E    E+N K +
Sbjct: 201 TTVEDIKNYFKAYGTIEEATLMFDKVTSRHRGFAFVTFDNESTVDKVCEIHFHEINSKMV 22

Query: 397 E 397
           E
Sbjct: 21  E 19

 Score = 30.4 bits (67), Expect = 2.3,   Method: Compositional matrix adjust.
 Identities = 15/45 (33%), Positives = 24/45 (53%)
 Frame = -1

Query: 166 VGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTF 210
           +G +      + L   FEK G I +  +M DP +  +RG+ FVT+
Sbjct: 552 IGGLSWQTTTETLRSYFEKFGEIKESMVMKDPTSKRSRGFGFVTY 418
>00029
          Length = 2204

 Score = 39.3 bits (90), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 16/64 (25%), Positives = 34/64 (53%)
 Frame = -3

Query: 340  LFVRNLANTVTEEILEKSFSQFGKLERVKKLKDYAFIHFDERDGAVKAMEEMNGKDLEGE 399
            +F+ NL +    E L   F ++G +     LK++ F+H  ++  A  A+  +NG ++ G+
Sbjct: 2130 IFIGNLGDDTDPEELRALFEKYGSVAECDVLKNFGFVHMVKKGEADDAISNLNGYNIGGQ 1951

Query: 400  NIEI 403
             + +
Sbjct: 1950 RMRV 1939

 Score = 29.3 bits (64), Expect = 4.5,   Method: Compositional matrix adjust.
 Identities = 21/79 (26%), Positives = 37/79 (46%)
 Frame = -3

Query: 163  EIFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKL 222
            +IF+G +  D   +EL  LFEK G + +  ++        + + FV    K  A +A+  
Sbjct: 2133 KIFIGNLGDDTDPEELRALFEKYGSVAECDVL--------KNFGFVHMVKKGEADDAISN 1978

Query: 223  YNNHEIRSGKHIGVCISVA 241
             N + I  G+ + V +S  
Sbjct: 1977 LNGYNI-GGQRMRVELSTG 1924
>04988
          Length = 705

 Score = 39.3 bits (90), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 20/68 (29%), Positives = 37/68 (54%)
 Frame = -3

Query: 340 LFVRNLANTVTEEILEKSFSQFGKLERVKKLKDYAFIHFDERDGAVKAMEEMNGKDLEGE 399
           +++  L     E+ +E+ F  +G++  +     Y F+ F++   A  A+ E+NGKDL GE
Sbjct: 646 VYIGRLPYQAREKDIERFFRGYGRVNDIMLKNGYGFVEFEDFRDADDAVYELNGKDLCGE 467

Query: 400 NIEIVFAK 407
            + I  A+
Sbjct: 466 RVIIEHAR 443
>00302
          Length = 927

 Score = 39.3 bits (90), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 25/67 (37%), Positives = 37/67 (55%)
 Frame = -1

Query: 175 EDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLYNNHEIRSGKHI 234
           E  L  +F + G I +++++ D  TG +RG+AFV F + E A EA    N  EI  G+ I
Sbjct: 426 ERGLREVFGRYGHISEVQVVYDRQTGRSRGFAFVYFKSSEDAHEAKDRCNGIEI-DGRKI 250

Query: 235 GVCISVA 241
            V  S+ 
Sbjct: 249 RVDFSIT 229
>23720
          Length = 739

 Score = 38.9 bits (89), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 20/68 (29%), Positives = 37/68 (54%)
 Frame = -1

Query: 340 LFVRNLANTVTEEILEKSFSQFGKLERVKKLKDYAFIHFDERDGAVKAMEEMNGKDLEGE 399
           +++  L     E+ +E+ F  +G++  +     Y F+ F++   A  A+ E+NGKDL GE
Sbjct: 679 VYIGRLPYQAREKDIERFFRGYGRVNDIMLKNGYGFVEFEDFRDADDAVYELNGKDLCGE 500

Query: 400 NIEIVFAK 407
            + I  A+
Sbjct: 499 RVIIEHAR 476
>33516
          Length = 449

 Score = 38.9 bits (89), Expect = 0.006,   Method: Composition-based stats.
 Identities = 20/48 (41%), Positives = 29/48 (60%)
 Frame = +1

Query: 163 EIFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTF 210
           +IFVG +  D  +D L   F + G I D  +MM+  TG +RG+ FV+F
Sbjct: 157 KIFVGGLSWDTDQDSLQGYFSQFGEITDCIVMMNQQTGKSRGFGFVSF 300
>02140
          Length = 1796

 Score = 38.1 bits (87), Expect = 0.010,   Method: Compositional matrix adjust.
 Identities = 24/87 (27%), Positives = 42/87 (48%), Gaps = 8/87 (9%)
 Frame = +3

Query: 329 PDPEVMAKVKVLFVRNLANTVTEEILEKSFSQFGKLERVKKLKD--------YAFIHFDE 380
           PD +      VLFV  L    T+E LE  FS+FG +   + ++D        YAF+ F++
Sbjct: 774 PDADTKPPDNVLFVCKLNPVTTDEDLEMIFSRFGPITSCEVIRDHKTKESLQYAFVEFEK 953

Query: 381 RDGAVKAMEEMNGKDLEGENIEIVFAK 407
            +    A  +M+   ++   I + F++
Sbjct: 954 PEHCENAYFKMDNVLIDDRRIHVDFSQ 1034

 Score = 32.7 bits (73), Expect = 0.41,   Method: Compositional matrix adjust.
 Identities = 37/130 (28%), Positives = 54/130 (41%), Gaps = 2/130 (1%)
 Frame = +3

Query: 121 EAKIKA-LLERTGYTLDVTTGQRKYGGPPPDSVYSGQQPSVGTEIFVGKIPRDLFEDELV 179
           EA+  A LLE  G   D  T        PPD+V           +FV K+     +++L 
Sbjct: 729 EARANAQLLEMVGDLPDADTK-------PPDNV-----------LFVCKLNPVTTDEDLE 854

Query: 180 PLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLYNNHEIRSGK-HIGVCI 238
            +F + GPI    ++ D  T  +  YAFV F   E  + A    +N  I   + H+    
Sbjct: 855 MIFSRFGPITSCEVIRDHKTKESLQYAFVEFEKPEHCENAYFKMDNVLIDDRRIHVDFSQ 1034

Query: 239 SVANNRLFVG 248
           SV+  R   G
Sbjct: 1035SVSKIRPMDG 1064
>35180
          Length = 2181

 Score = 37.4 bits (85), Expect = 0.018,   Method: Compositional matrix adjust.
 Identities = 38/118 (32%), Positives = 53/118 (44%), Gaps = 10/118 (8%)
 Frame = -2

Query: 121 EAKIKALLERTGYTL----DVTTGQRKYGGPPPDSVYSGQQPSVGTEIFVGKIPRDLFED 176
           EA  KAL + T   +    D+T  +R    P PD+    +       ++V   P D+  D
Sbjct: 395 EAICKALQKSTAGLMEVNEDMTKIRRCPSKPLPDNTKERKDDINSRSVYVKGFPEDITLD 216

Query: 177 ELVPLFEKAGPIWDLRLMMDPLTGLN-RGYAFVTFCTKEAAQEAVKL-----YNNHEI 228
            L+  FE+ G I D  LM       N +G  FVTF  KE  +E V L     YN+ E+
Sbjct: 215 TLMEFFEQHGKI-DTILMRRNRPDKNFKGSVFVTFSNKE--EEDVFLGKDVKYNDTEL 51
>25632
          Length = 864

 Score = 37.4 bits (85), Expect = 0.019,   Method: Compositional matrix adjust.
 Identities = 19/64 (29%), Positives = 34/64 (53%)
 Frame = -2

Query: 340 LFVRNLANTVTEEILEKSFSQFGKLERVKKLKDYAFIHFDERDGAVKAMEEMNGKDLEGE 399
           + +RNL   V    LEK    +G +E    LK+Y F+H   +  A  A+  +NG +++G+
Sbjct: 743 VMIRNLMTFVC--CLEK----YGTVEECDVLKNYGFVHMPTKSEASAAITNLNGYNIKGQ 582

Query: 400 NIEI 403
            + +
Sbjct: 581 RMRV 570
>01937
          Length = 1320

 Score = 37.0 bits (84), Expect = 0.021,   Method: Compositional matrix adjust.
 Identities = 20/62 (32%), Positives = 32/62 (51%)
 Frame = -1

Query: 149  PDSVYSGQQPSVGTEIFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFV 208
            P  + S    +  ++IFVG +      ++    F+  G I +  LM D +T  +RG+AFV
Sbjct: 1254 PHCIDSKTMVTKTSKIFVGGLSSSTTVEDXKNYFKAYGTIEEATLMFDKVTSRHRGFAFV 1075

Query: 209  TF 210
            TF
Sbjct: 1074 TF 1069
>32386
          Length = 674

 Score = 37.0 bits (84), Expect = 0.026,   Method: Compositional matrix adjust.
 Identities = 18/57 (31%), Positives = 31/57 (54%)
 Frame = +1

Query: 163 EIFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEA 219
           ++F+G +  +  ED L   FE  G I D  +M D  +  +RG+ F+T+   E+  +A
Sbjct: 304 KLFIGGLSYETDEDSLRSHFETWGEIVDCIVMRDSNSKRSRGFGFITYKDAESIDQA 474

 Score = 31.2 bits (69), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 28/104 (26%), Positives = 51/104 (49%), Gaps = 1/104 (0%)
 Frame = +1

Query: 244 RLFVGSIPKSKTKEQILEEFSKVTEGLTDVILYHQPDDKKKNRGFCFLEYEDHKTAAQAR 303
           +LF+G +     ++ +   F    E + D I+    +  K++RGF F+ Y+D ++  QA+
Sbjct: 304 KLFIGGLSYETDEDSLRSHFETWGE-IVDCIVMRDSN-SKRSRGFGFITYKDAESIDQAQ 477

Query: 304 RRLMSGKVKVWGNVGTVEWADPIEDPD-PEVMAKVKVLFVRNLA 346
               +   K+ G     + A P E+    EV   VK +FV +L+
Sbjct: 478 ---ANRPHKIDGREVDTKRAMPREESGRSEVQQSVKKMFVGSLS 600
>17175
          Length = 512

 Score = 36.2 bits (82), Expect = 0.036,   Method: Composition-based stats.
 Identities = 18/45 (40%), Positives = 28/45 (62%), Gaps = 1/45 (2%)
 Frame = -3

Query: 148 PPDSVYSGQQPSVGT-EIFVGKIPRDLFEDELVPLFEKAGPIWDL 191
           P   V S  +P   + ++FVG+IPR++ E+EL  +FE  GP+  L
Sbjct: 135 PSTQVTSQGEPDADSIKMFVGQIPRNMDENELRKMFEDYGPVHSL 1
>12506
          Length = 1056

 Score = 35.8 bits (81), Expect = 0.046,   Method: Compositional matrix adjust.
 Identities = 21/71 (29%), Positives = 36/71 (50%), Gaps = 8/71 (11%)
 Frame = -3

Query: 346  ANTVTEEILEKSFSQFGKLERVK--------KLKDYAFIHFDERDGAVKAMEEMNGKDLE 397
            A  V +++L  +F  FG +  ++        K + +AFI F+  + A  A++ MN  +L 
Sbjct: 1039 AGEVDDKVLHAAFLPFGDIVDIQIPLDYETEKHRGFAFIEFELAEDAAAAIDNMNESELF 860

Query: 398  GENIEIVFAKP 408
            G  I +  AKP
Sbjct: 859  GRTIRVNLAKP 827

 Score = 30.4 bits (67), Expect = 2.0,   Method: Compositional matrix adjust.
 Identities = 21/79 (26%), Positives = 38/79 (48%)
 Frame = -3

Query: 161  GTEIFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAV 220
            G+    G++   +     +P     G I D+++ +D  T  +RG+AF+ F   E A  A+
Sbjct: 1054 GSLFTAGEVDDKVLHAAFLPF----GDIVDIQIPLDYETEKHRGFAFIEFELAEDAAAAI 887

Query: 221  KLYNNHEIRSGKHIGVCIS 239
               N  E+  G+ I V ++
Sbjct: 886  DNMNESEL-FGRTIRVNLA 833
>29364
          Length = 1126

 Score = 35.4 bits (80), Expect = 0.064,   Method: Compositional matrix adjust.
 Identities = 18/55 (32%), Positives = 30/55 (54%)
 Frame = +1

Query: 349 VTEEILEKSFSQFGKLERVKKLKDYAFIHFDERDGAVKAMEEMNGKDLEGENIEI 403
           V E  LE+ F  +G+   +     Y F+ F++   A  A+ E+NGK+L GE + +
Sbjct: 1   VRERDLERFFKGYGRTRDILIKNGYGFVEFEDYRDADDAVYELNGKELLGERVVV 165
>24983
          Length = 433

 Score = 35.4 bits (80), Expect = 0.073,   Method: Composition-based stats.
 Identities = 25/88 (28%), Positives = 41/88 (46%)
 Frame = -2

Query: 165 FVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLYN 224
            +G +P    +  L   F+K G I +  ++ D  TG +RGY FVT   +  A  A K  +
Sbjct: 306 LLGGLPYHTTDHSLREYFDKFGDIDEAVVITDRQTGKSRGYGFVTMADRTGADRACK--D 133

Query: 225 NHEIRSGKHIGVCISVANNRLFVGSIPK 252
            + I  G+   V      N  ++G+ P+
Sbjct: 132 PNPIIDGRKANV------NLAYIGAKPR 67
>26197
          Length = 1365

 Score = 35.4 bits (80), Expect = 0.077,   Method: Compositional matrix adjust.
 Identities = 28/95 (29%), Positives = 38/95 (40%), Gaps = 7/95 (7%)
 Frame = -2

Query: 147  PPPDSVYSGQQPSVGTE-------IFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLT 199
               ++V S Q    G E       IFVG +  +     L   FEK G +    L  D  +
Sbjct: 1364 SDSEAVVSTQSGHYGREENEDDRKIFVGGLSWETSSKHLREYFEKFGEVTSCTLKTDLDS 1185

Query: 200  GLNRGYAFVTFCTKEAAQEAVKLYNNHEIRSGKHI 234
            G +RG+ FV F  KEA      + N      G+ I
Sbjct: 1184 GKSRGFGFVVF--KEAVTVDAVVKNKEHKLQGRKI 1086
>30934
          Length = 809

 Score = 35.0 bits (79), Expect = 0.098,   Method: Compositional matrix adjust.
 Identities = 17/37 (45%), Positives = 24/37 (64%)
 Frame = +1

Query: 183 EKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEA 219
           +K GP+ DL L +DP+T   +G+A VTF   E A +A
Sbjct: 19  DKGGPVTDLDLPVDPITKKIKGFAHVTFMFPEHAVKA 129
>03903
          Length = 983

 Score = 34.3 bits (77), Expect = 0.14,   Method: Compositional matrix adjust.
 Identities = 26/81 (32%), Positives = 44/81 (54%), Gaps = 8/81 (9%)
 Frame = -1

Query: 164 IFVGKIPRDLFEDELVPLF--------EKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEA 215
           +++  + + + E++L  +F        E+   I+D+RLM +   G  +G AFVT  T+E 
Sbjct: 452 LYIKNLSKQVTEEDLHWVFGRYVNWDKEEEKSIFDIRLMKE---GRMKGQAFVTLGTEEQ 282

Query: 216 AQEAVKLYNNHEIRSGKHIGV 236
           A++AVK  N   +  GK I V
Sbjct: 281 ARKAVKDTNAF-VFKGKPIAV 222
>01065
          Length = 1033

 Score = 33.5 bits (75), Expect = 0.30,   Method: Compositional matrix adjust.
 Identities = 19/69 (27%), Positives = 36/69 (52%), Gaps = 3/69 (4%)
 Frame = +2

Query: 346 ANTVTEEILEKSFSQFGKLERV---KKLKDYAFIHFDERDGAVKAMEEMNGKDLEGENIE 402
           ++T T EI E+ F +FG +  +   +     AF+ +   + A KA+  M+G+ + G  + 
Sbjct: 41  SSTSTREIREE-FKRFGDIIDLWMPRTQPTIAFVVYRYEEDAEKAIRRMDGESMHGRRVR 217

Query: 403 IVFAKPPDQ 411
           +  A+P  Q
Sbjct: 218 VSLARPRSQ 244
>25950
          Length = 417

 Score = 33.1 bits (74), Expect = 0.33,   Method: Compositional matrix adjust.
 Identities = 19/79 (24%), Positives = 37/79 (46%)
 Frame = -2

Query: 164 IFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLY 223
           ++VG +      +EL   F   G I  + ++ +   G  +G+A++ F +KE  + A+ + 
Sbjct: 275 VYVGNVDYGASAEELEAHFHGCGTINRVTILCNKADGHPKGFAYIEFGSKEYVETALAM- 99

Query: 224 NNHEIRSGKHIGVCISVAN 242
            N  +  G+ I V     N
Sbjct: 98  -NETLFRGRQIKVMTKRTN 45
>00738
          Length = 1559

 Score = 33.1 bits (74), Expect = 0.34,   Method: Compositional matrix adjust.
 Identities = 19/69 (27%), Positives = 36/69 (52%), Gaps = 3/69 (4%)
 Frame = -2

Query: 346  ANTVTEEILEKSFSQFGKLERV---KKLKDYAFIHFDERDGAVKAMEEMNGKDLEGENIE 402
            ++T T EI E+ F +FG +  +   +     AF+ +   + A KA+  M+G+ + G  + 
Sbjct: 1240 SSTSTREIREE-FKRFGDIIDLWMPRTQPTIAFVVYRYEEDAEKAIRRMDGESMHGRRVR 1064

Query: 403  IVFAKPPDQ 411
            +  A+P  Q
Sbjct: 1063 VSLARPRSQ 1037
>28605
          Length = 697

 Score = 32.0 bits (71), Expect = 0.67,   Method: Compositional matrix adjust.
 Identities = 19/56 (33%), Positives = 32/56 (57%), Gaps = 2/56 (3%)
 Frame = -3

Query: 340 LFVRNLANTVTEEI-LEKSFSQFGK-LERVKKLKDYAFIHFDERDGAVKAMEEMNG 393
           +FV NL++  T E  L++ FS++G  L+ +     Y F+ F   +   +A+E MNG
Sbjct: 563 VFVANLSSDETSEAELQELFSKYGNVLDTLVHHNRYGFVQFSTEEEGRRAVEAMNG 396
>11126
          Length = 1061

 Score = 30.8 bits (68), Expect = 1.7,   Method: Compositional matrix adjust.
 Identities = 18/73 (24%), Positives = 34/73 (46%)
 Frame = -3

Query: 164 IFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLY 223
           ++VG +      +EL   F   G +  + ++ D  +G  +G+A+V F  K++   A K  
Sbjct: 624 VYVGNVDYGATAEELEQHFHGCGSVNRVTILCDKYSGHPKGFAYVEFADKDSVVTA-KCT 448

Query: 224 NNHEIRSGKHIGV 236
               +  G+ I V
Sbjct: 447 GMDSLFRGRQIKV 409
>05273
          Length = 1009

 Score = 30.4 bits (67), Expect = 2.1,   Method: Compositional matrix adjust.
 Identities = 16/43 (37%), Positives = 23/43 (53%)
 Frame = -1

Query: 182 FEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLYN 224
           F+K G I +  ++ D  TG +RGY FVT   + A  E  +  N
Sbjct: 139 FDKFGDIDEAVVITDRQTGKSRGYGFVTMADRRARTEPARTPN 11
>02809
          Length = 1475

 Score = 30.4 bits (67), Expect = 2.1,   Method: Compositional matrix adjust.
 Identities = 22/78 (28%), Positives = 39/78 (50%), Gaps = 1/78 (1%)
 Frame = -1

Query: 159  SVGTEIFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQE 218
            S+  +++VG++     + EL   F K GP+ ++ +   P      G+AFV F     A++
Sbjct: 1343 SLDCKVYVGELGHGCAKQELEDKFAKYGPLKNVWVARRPA-----GFAFVEFEDNRDAED 1179

Query: 219  AVK-LYNNHEIRSGKHIG 235
            AV+ L  + + RS    G
Sbjct: 1178 AVQALDGSADXRSAGACG 1125
>20169
          Length = 1364

 Score = 30.0 bits (66), Expect = 2.9,   Method: Compositional matrix adjust.
 Identities = 19/70 (27%), Positives = 35/70 (50%)
 Frame = -1

Query: 159  SVGTEIFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQE 218
            S+  +++VG++     + EL   F K GP+ ++ +   P      G+AFV F     A++
Sbjct: 1079 SLDCKVYVGELGHGCAKQELEDKFAKYGPLKNVWVARRPA-----GFAFVEFEDNRDAED 915

Query: 219  AVKLYNNHEI 228
            AV+  +   I
Sbjct: 914  AVQALDGARI 885
>00781
          Length = 3170

 Score = 30.0 bits (66), Expect = 3.1,   Method: Compositional matrix adjust.
 Identities = 16/44 (36%), Positives = 24/44 (54%)
 Frame = -1

Query: 181  LFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLYN 224
            +F K G +  + L     T   +GYAFV F + E A +AV++ N
Sbjct: 2663 MFSKCGTVTYVSLPCFKTTREIKGYAFVEFQSPEEAVKAVQMLN 2532

 Score = 28.9 bits (63), Expect = 6.7,   Method: Compositional matrix adjust.
 Identities = 16/64 (25%), Positives = 32/64 (50%), Gaps = 8/64 (12%)
 Frame = -1

Query: 337  VKVLFVRNLANTVTEEILEKSFSQFGKLERV--------KKLKDYAFIHFDERDGAVKAM 388
             + ++V       + E + + FS+ G +  V        +++K YAF+ F   + AVKA+
Sbjct: 2723 ARTVYVEGFHKFTSREWISRMFSKCGTVTYVSLPCFKTTREIKGYAFVEFQSPEEAVKAV 2544

Query: 389  EEMN 392
            + +N
Sbjct: 2543 QMLN 2532
>13457
          Length = 4857

 Score = 28.5 bits (62), Expect = 7.7,   Method: Compositional matrix adjust.
 Identities = 25/93 (26%), Positives = 45/93 (48%), Gaps = 10/93 (10%)
 Frame = -1

Query: 340  LFVRNLANTVTEEILEKSFSQFGKLERVKKLKD-------YAFIHFDERDGAVKAMEEMN 392
            LFV  L    TEE + + F  +G +E    L+D        AF+ +     A  A+  ++
Sbjct: 3402 LFVGMLNKQQTEEDVRQLFHPYGAIEECTILRDQNGNSKGCAFVKYSTHSEAQAAINALH 3223

Query: 393  G-KDLEGENIEIV--FAKPPDQKRKERKAQRQA 422
            G + + G +  +V  FA   +++R+ R+ Q+ A
Sbjct: 3222 GSQTMPGASSSLVVKFAD-TEKERQLRRMQQMA 3127
>19556
          Length = 917

 Score = 28.5 bits (62), Expect = 8.7,   Method: Compositional matrix adjust.
 Identities = 20/76 (26%), Positives = 36/76 (47%), Gaps = 9/76 (11%)
 Frame = -1

Query: 341 FVRNLANTVTEEILEKSFSQFGKLERVK--------KLKDYAFIHFD-ERDGAVKAMEEM 391
           F+  L   VTEE L + FS+FG++  V           + +A+++   E +G  K     
Sbjct: 821 FIGGLVKGVTEEELMEKFSRFGQVSNVDIKTRTNGIDSRTFAYVNLTAEENGFKKCFTAY 642

Query: 392 NGKDLEGENIEIVFAK 407
           N    +G  +++ +AK
Sbjct: 641 NNTKWKGGQLKLQYAK 594
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6678483|ref|NP_033483.1| ubiquitin-activating enzyme
E1 isoform 1 [Mus musculus]
         (1058 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

34235                                                                 228   e-100
19711                                                                 173   9e-88
21876                                                                 288   8e-78
25566                                                                 250   2e-66
00369                                                                 120   3e-27
21008                                                                 116   4e-26
06604                                                                 115   1e-25
20367                                                                  76   6e-14
14935                                                                  36   0.066
>34235
          Length = 1026

 Score =  228 bits (580), Expect(3) = e-100,   Method: Compositional matrix adjust.
 Identities = 110/194 (56%), Positives = 134/194 (69%), Gaps = 1/194 (0%)
 Frame = -1

Query: 741 FWSGPKRCPHPLTFDVNNTLHLDYVMAAANLFAQTYGLTGSQDRAAVASLLQSVQVPEFT 800
           FWSGPKRCPH L FD +N LHLDY+ AAAN+     GL   +DRAA+  ++  V VPEF 
Sbjct: 876 FWSGPKRCPHALEFDADNELHLDYIEAAANMKGFMCGLPPVRDRAAIKDMVSKVMVPEFV 697

Query: 801 PKSGVKIHVSDQELQSANA-SVDDSRLEELKATLPSPDKLPGFKMYPIDFEKDDDSNFHM 859
           P+SG+KI V+D E Q+ N  + D   +E+LK+ LPSPD+L G ++  +DFEKDDD+NFHM
Sbjct: 696 PRSGIKIAVTDAEAQAGNNDNFDKDTVEKLKSALPSPDELKGRQLNAVDFEKDDDTNFHM 517

Query: 860 DFIVAASNLRAENYDISPADRHKSKLXXXXXXXXXXXXXXXVVGLVCLELYKVVQGHQQL 919
           DFI AASNLRAENY I PADRHKSKL               VVGLV LEL K+ QGH  +
Sbjct: 516 DFITAASNLRAENYSIPPADRHKSKLIAGRIIPAIATTTAMVVGLVGLELIKLAQGHTNV 337

Query: 920 DSYKNGFLNLALPF 933
           + +KNGF NLALP 
Sbjct: 336 ERFKNGFANLALPL 295

 Score =  124 bits (312), Expect(3) = e-100,   Method: Compositional matrix adjust.
 Identities = 63/107 (58%), Positives = 81/107 (75%)
 Frame = -2

Query: 931  LPFFGFSEPLAAPRHQYYNQEWTLWDRFEVQGLQPNGEEMTLKQFLDYFKTEHKLEITML 990
            L  F FSEP+ AP+ +YY +E+TLWDRF VQG      E+TL+QFLDYF+ EH LEITML
Sbjct: 305  LSLFAFSEPILAPKSKYYEKEFTLWDRFTVQG------EITLQQFLDYFQKEHGLEITML 144

Query: 991  SQGVSMLYSFFMPAAKLKERLDQPMTEIVSRVSKRKLGRHVRALVLE 1037
            SQGV +L+S FM  AK +ER +  ++E+V +VSK+K+  HVRALVLE
Sbjct: 143  SQGVCLLFSNFMQPAKQEERKNLLISELVKKVSKKKIPPHVRALVLE 3

 Score = 55.1 bits (131), Expect(3) = e-100,   Method: Compositional matrix adjust.
 Identities = 25/55 (45%), Positives = 36/55 (65%)
 Frame = -3

Query: 692  QRSLVLQRPQTWGDCVTWACHHWHTQYCNNIRQLLHNFPPDQLTSSGAPFWSGPK 746
            +R++  +   ++  CV WA + + T Y N I+QLL NFP DQ+TSSGAPF  G +
Sbjct: 1024 KRTVNTEFFTSFDKCVEWARNLFQTNYSNQIKQLLFNFPSDQMTSSGAPFLVGSQ 860
>19711
          Length = 1114

 Score =  173 bits (438), Expect(2) = 9e-88,   Method: Compositional matrix adjust.
 Identities = 88/190 (46%), Positives = 121/190 (63%), Gaps = 1/190 (0%)
 Frame = +2

Query: 378 LDEDLIRKLAYVAAGDLAPINAFIGGLAAQEVMKACSGKFMPIMQWLYFDALECLPEDKE 437
           ++E ++R L++ A G LAP+ A +GG+ AQE +KA +GKF+P+ QWLY DA+E +PE   
Sbjct: 545 VEEKIVRCLSHTARGSLAPLCAAMGGIVAQEGLKALTGKFLPLSQWLYLDAMETIPE-LS 721

Query: 438 ALTEEKCLPRQNRYDGQVAVFGSDFQEKLSKQKYFLVGAGAIGCELLKNFAMIGLGCXXX 497
             + E    R +R D      G D  +KL+  + F+VG GAIGCE+LKN+A++GLG    
Sbjct: 722 VTSPEAFQLRNDRLDPLRICVGEDVCQKLADTRLFMVGCGAIGCEMLKNYALLGLGAGQK 901

Query: 498 XXXXXTDMDTIEKSNLNRQFLFRPWDVTKLKSDTAAAAVRQMNPYIQVTSHQNRVGPDTE 557
                TD D IEKSNLNRQFLFR   + K KS TAA +V  +NP + + + QN+V P TE
Sbjct: 902 GQITITDNDLIEKSNLNRQFLFRSHHIQKPKSTTAAQSVLDINPALHIQAQQNKVCPQTE 1081

Query: 558 RI-YDDDFFQ 566
              Y D FF+
Sbjct: 1082STHYPDAFFE 1111

 Score =  170 bits (431), Expect(2) = 9e-88,   Method: Compositional matrix adjust.
 Identities = 86/171 (50%), Positives = 108/171 (63%), Gaps = 2/171 (1%)
 Frame = +3

Query: 200 CDFGEEMVLTDSNGEQPLSAMVSMVTKDNPGVVTCLDEARHGFETGDFVSFSEVQGMIQL 259
           CDFG+   + D  GE+     ++ +TK NPGVVTCLD   HG ETGD V+F EV+GM QL
Sbjct: 3   CDFGDTFEVMDPTGEEAKEVFIANITKANPGVVTCLDNLLHGLETGDLVTFKEVKGMEQL 182

Query: 260 NGCQPMEIKVLGPYTFSICDTSN--FSDYIRGGIVSQVKVPKKISFKSLPASLVEPDFVM 317
           N  Q   IKVL P TFSIC+TS   F  Y  GGI+SQVKVPK + FKSL   LV P  +M
Sbjct: 183 NS-QQCAIKVLSPTTFSICNTSGSEFGAYESGGIISQVKVPKSVHFKSLEEQLVSPSLLM 359

Query: 318 TDFAKYSRPAQLHIGFQALHQFCALHNQPPRPRNEEDATELVGLAQAVNAR 368
            D  K++ P  +H+ FQALHQF A     P+P   + A  +V LA+A +A+
Sbjct: 360 PDLCKFTAPGNIHVAFQALHQFWAETGSLPQPWCSDSADRMVLLAKACSAK 512
>21876
          Length = 894

 Score =  288 bits (737), Expect = 8e-78,   Method: Compositional matrix adjust.
 Identities = 152/306 (49%), Positives = 206/306 (67%), Gaps = 10/306 (3%)
 Frame = -1

Query: 44  NGSEADIDESLYSRQLYVLGHEAMKM---LQTSSVLVSGLRGLGVEIAKNIILGGVKAVT 100
           NG+  DIDE L        GHEAM+    LQ S +   G  GLG+EIAKN++LGGVK+V+
Sbjct: 894 NGAADDIDEGLVXSPAVCAGHEAMRKMAKLQCSDLWAMG--GLGIEIAKNVVLGGVKSVS 721

Query: 101 LHDQGTTQWADLSSQFYLREEDIGKNRAEVSQPRLAELNSYVPVTAYTGPLVEDFLSSFQ 160
           +HD G   + DLSSQF+LR+ED+GKNRAEVSQPRLAELNSYVP+++ TG    DF     
Sbjct: 720 IHDPGKVVFGDLSSQFFLRDEDVGKNRAEVSQPRLAELNSYVPISSSTG----DFG*GLL 553

Query: 161 VVVLTNSPLEAQLRVGEFCHSRGIKLVVADTRGLFG-------QLFCDFGEEMVLTDSNG 213
           V V   S  +  +R  + C   G  L ++  +   G       +   DFG   V+TD +G
Sbjct: 552 VQVSGGSTDQLFVR*TDPC---GRVLSLSQHQVHCGRNAWTVWENLLDFGSNFVITDGDG 382

Query: 214 EQPLSAMVSMVTKDNPGVVTCLDEARHGFETGDFVSFSEVQGMIQLNGCQPMEIKVLGPY 273
           EQP+S M++ + K +  VV  +DE +HG E GD+V+F EVQGM +LNGC+P++IKVLGPY
Sbjct: 381 EQPISCMIADIEKGDNSVVATVDETKHGLEDGDYVTFKEVQGMTELNGCKPVKIKVLGPY 202

Query: 274 TFSICDTSNFSDYIRGGIVSQVKVPKKISFKSLPASLVEPDFVMTDFAKYSRPAQLHIGF 333
           TFSI DT+ ++DYIRGG  +QVK+PK I+FKS+ A++  P+ + +DFAK+ RP QLHI F
Sbjct: 201 TFSIGDTTKYADYIRGGTATQVKMPKTINFKSIKAAMDAPEILPSDFAKFDRPPQLHIAF 22

Query: 334 QALHQF 339
           +AL ++
Sbjct: 21  KALSEY 4
>25566
          Length = 1639

 Score =  250 bits (639), Expect = 2e-66,   Method: Compositional matrix adjust.
 Identities = 168/467 (35%), Positives = 246/467 (52%), Gaps = 11/467 (2%)
 Frame = +2

Query: 600  TLGTKGNVQVVIPFLTESYSSSQDPPEKSIPICTLKNFPNAIEHTLQWARDEFEGLFKQP 659
            T+GTKG+VQV+IP LTESY+S QDP ++  P CT+K+FP  IEH +QWARD+FE L+   
Sbjct: 2    TMGTKGHVQVIIPHLTESYTSQQDPADEDYPYCTVKSFPATIEHCIQWARDKFEELYVNQ 181

Query: 660  AENVNQYLTDSKFVERTLRLAGTQPLEVLEAVQR--SLVLQRPQTWGDCVTWACHHWHTQ 717
                N++L  +   + T  +   +  +V++   R   +   RP +W DCV  A   +   
Sbjct: 182  PNLFNKFLASN--ADMTAVVHKLKSGDVVDGGLRVSKMAATRPHSWEDCVRLARIRFEKY 355

Query: 718  YCNNIRQLLHNFPPDQLTSSGAPFWSGPKRCPHPLTFDVNNTLHLDYVMAAANLFAQTYG 777
            + +  RQLLH FP D      + FW  PKR P PL F+ ++ LH+ +V + A L    Y 
Sbjct: 356  FNHKARQLLHAFPLDIKLPDNSLFWQSPKRPPTPLQFNADDPLHMTFVTSTARLLCDIYA 535

Query: 778  LTGSQDRA--AVASLLQSVQVPEFTPKSGVKIHVSDQ------ELQSANASVDDSRLEEL 829
            ++ S   +  ++ ++L +V VP F P S  KI   +       E QS+   V  +     
Sbjct: 536  ISYSTQVSTDSIKTILHAVTVPAFVP-SDKKIETDETKSQQEAEPQSSGDEVTAAGERLA 712

Query: 830  KATLPSPDKLPGFKMYPIDFEKDDDSNFHMDFIVAASNLRAENYDISPADRHKSKLXXXX 889
            +  + S  +     M  ++FEKDDDSN H++FI A SN+RA+ Y I   DR K K     
Sbjct: 713  QVVMSSQAQSALQPMAALEFEKDDDSNDHINFIAACSNMRAQMYSIENVDRLKIKRIAGR 892

Query: 890  XXXXXXXXXXXVVGLVCLELYKVVQGHQQLDSYKNGFLNLALPFFGFSEPLAAPRHQYYN 949
                       V GLV +EL KV+Q  + LD++KN FLNLALP    SEP A  R     
Sbjct: 893  IVPAIATTTAAVSGLVTIELIKVLQ-QRPLDAFKNAFLNLALPMLLLSEPGACARKVLKE 1069

Query: 950  Q-EWTLWDRFEVQGLQPNGEEMTLKQFLDYFKTEHKLEITMLSQGVSMLYSFFMPAAKLK 1008
                ++WD++ ++G Q    + TL+QFLD  K     E T +  GV ++Y   MP    K
Sbjct: 1070 GLSVSVWDKWTIRGKQ----DFTLQQFLDSCKDSFGFEATAVVNGVKIIYMPIMPPH--K 1231

Query: 1009 ERLDQPMTEIVSRVSKRKLGRHVRALVLELCCNDESGEDVEVPYVRY 1055
            +RL Q M +++      K    +  + L +C  D+ GE++E P VRY
Sbjct: 1232 KRLPQTMMKLI------KPEPGITYVDLVVCFEDDKGEEIEGPPVRY 1354
>00369
          Length = 1082

 Score =  120 bits (302), Expect = 3e-27,   Method: Compositional matrix adjust.
 Identities = 71/207 (34%), Positives = 109/207 (52%), Gaps = 14/207 (6%)
 Frame = +3

Query: 470 KYFLVGAGAIGCELLKNFAMIGLGCXXXXXXXXTDMDTIEKSNLNRQFLFRPWDVTKLKS 529
           K  ++GAG +GCELLK+ A++G            DMDTI+ SNLNRQFLFRP DV   K+
Sbjct: 222 KLLVIGAGGLGCELLKDLALMGF-----FDIHVIDMDTIDVSNLNRQFLFRPKDVGSPKA 386

Query: 530 DTAAAAVRQMNPYIQVTSHQNRVGPDTERIYDDDFFQNLDGVANALDNIDARMYMDRRCV 589
           + AAA +    P  +VT H  ++     + YD+ F++    +   LD+I AR +++   +
Sbjct: 387 EVAAAFINSRVPGCKVTPHFAKI-----QDYDESFYRGFHVIVCGLDSIIARRWINSMLI 551

Query: 590 YYRK------------PLLESGTLGTKGNVQVVIPFLTESYSSSQD--PPEKSIPICTLK 635
                           PL++ GT G KGN +VV+P +T     + D  PP+ + P+CT+ 
Sbjct: 552 SLLNYEDGELDQSSIIPLVDGGTEGFKGNARVVLPGITACIECTLDLYPPQVNFPLCTIA 731

Query: 636 NFPNAIEHTLQWARDEFEGLFKQPAEN 662
           + P   EH +++ R     +   P EN
Sbjct: 732 HTPRLPEHCIEYVR-----ILLWPKEN 797

 Score = 52.0 bits (123), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 47/147 (31%), Positives = 64/147 (43%), Gaps = 18/147 (12%)
 Frame = +3

Query: 69  MLQTSSVLVSGLRGLGVEIAKNIILGGVKAVTLHDQGTTQWADLSSQFYLREEDIGKNRA 128
           M +T  +LV G  GLG E+ K++ L G   + + D  T   ++L+ QF  R +D+G  +A
Sbjct: 207 MKETCKLLVIGAGGLGCELLKDLALMGFFDIHVIDMDTIDVSNLNRQFLFRPKDVGSPKA 386

Query: 129 EVSQPRLAELNSYVPVTAYTGPLV------EDFLSSFQVVVL----------TNSPLEAQ 172
           EV+    A +NS VP    T          E F   F V+V            NS L + 
Sbjct: 387 EVAA---AFINSRVPGCKVTPHFAKIQDYDESFYRGFHVIVCGLDSIIARRWINSMLISL 557

Query: 173 LRV--GEFCHSRGIKLVVADTRGLFGQ 197
           L    GE   S  I LV   T G  G 
Sbjct: 558 LNYEDGELDQSSIIPLVDGGTEGFKGN 638
>21008
          Length = 408

 Score =  116 bits (291), Expect = 4e-26,   Method: Compositional matrix adjust.
 Identities = 63/128 (49%), Positives = 85/128 (66%), Gaps = 2/128 (1%)
 Frame = +3

Query: 19  PGSNCSPAQSALSEVSSVPTNGMAKNGSEADIDESLYSRQLYVLGHEAMKMLQTSSVLVS 78
           PG NC        +++   T  MA   S+ +ID+SLYSRQ YVLG  AMK +  SSVL+ 
Sbjct: 54  PGFNCF-------KINLCNTETMA---SDMEIDDSLYSRQRYVLGDSAMKRMAQSSVLIH 203

Query: 79  GLRGLGVEIAKNIILGGVKAVTLHDQGTTQWADLSSQFYLREEDI--GKNRAEVSQPRLA 136
           GL GLG+EIAKNI+L GVK++T+ D  T+  +DL +QF++R+ D+   KNRAE    +LA
Sbjct: 204 GLGGLGIEIAKNIVLAGVKSLTVQDSKTSCTSDLGTQFFVRQADVDAAKNRAEACAGKLA 383

Query: 137 ELNSYVPV 144
           ELN YV +
Sbjct: 384 ELNPYVKI 407
>06604
          Length = 1748

 Score =  115 bits (287), Expect = 1e-25,   Method: Compositional matrix adjust.
 Identities = 61/154 (39%), Positives = 88/154 (57%), Gaps = 3/154 (1%)
 Frame = -2

Query: 53   SLYSRQLYVLGHEAMKMLQTSSVLVSGLRGLGVEIAKNIILGGVKAVTLHDQGTTQWADL 112
            +LY RQ+ + G +A + L+ +SVL+ G+RGLG E+AKNI+L G+K++TL D       D 
Sbjct: 1735 ALYDRQIRLWGLDAQRRLRAASVLLVGVRGLGAEVAKNIVLAGIKSLTLLDPSLADEEDT 1556

Query: 113  SSQFYLREEDIGKNRAEVSQPRLAELNSYVPVTAYTGPL---VEDFLSSFQVVVLTNSPL 169
            ++QF +   +IGKNRAE S  R   LN  V VTA T  +    +DF++SF VV  T   +
Sbjct: 1555 AAQFLIPRSEIGKNRAEASLERTQLLNPMVTVTADTCSIDDKDDDFVTSFDVVCATGCGV 1376

Query: 170  EAQLRVGEFCHSRGIKLVVADTRGLFGQLFCDFG 203
                R+   C   G+     D  G +G +F D G
Sbjct: 1375 STLRRLDRVCRDAGVMFYAGDVFGFYGYMFADLG 1274

 Score = 46.6 bits (109), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 33/138 (23%), Positives = 58/138 (42%)
 Frame = -2

Query: 451  YDGQVAVFGSDFQEKLSKQKYFLVGAGAIGCELLKNFAMIGLGCXXXXXXXXTDMDTIEK 510
            YD Q+ ++G D Q +L      LVG   +G E+ KN  + G+           D    ++
Sbjct: 1729 YDRQIRLWGLDAQRRLRAASVLLVGVRGLGAEVAKNIVLAGI-----KSLTLLDPSLADE 1565

Query: 511  SNLNRQFLFRPWDVTKLKSDTAAAAVRQMNPYIQVTSHQNRVGPDTERIYDDDFFQNLDG 570
             +   QFL    ++ K +++ +    + +NP + VT+    +        DDDF  + D 
Sbjct: 1564 EDTAAQFLIPRSEIGKNRAEASLERTQLLNPMVTVTADTCSIDDK-----DDDFVTSFDV 1400

Query: 571  VANALDNIDARMYMDRRC 588
            V      +     +DR C
Sbjct: 1399 VCATGCGVSTLRRLDRVC 1346

 Score = 35.4 bits (80), Expect = 0.14,   Method: Compositional matrix adjust.
 Identities = 26/100 (26%), Positives = 43/100 (43%), Gaps = 3/100 (3%)
 Frame = -3

Query: 334  QALHQFCALHNQPPRP---RNEEDATELVGLAQAVNARSPPSVKQNSLDEDLIRKLAYVA 390
            +AL +F  L  Q  RP     E D  +L  L      R        + D  +        
Sbjct: 1044 KALLEF--LEQQKRRPATSSQESDCQQLSKL------RXQXLZSXGAGDNKMAEDFTQYC 889

Query: 391  AGDLAPINAFIGGLAAQEVMKACSGKFMPIMQWLYFDALE 430
             G L+P+ A +GG+  QE++KA S K +P   + +++  +
Sbjct: 888  FGQLSPVCAVVGGILGQEIIKAVSQKDIPHNNFFFYNGTD 769
>20367
          Length = 859

 Score = 76.3 bits (186), Expect = 6e-14,   Method: Composition-based stats.
 Identities = 50/155 (32%), Positives = 74/155 (47%), Gaps = 11/155 (7%)
 Frame = -1

Query: 55  YSRQLYVLGHEAMKMLQTSSVLVSGLRGLGVEIAKNIILGGVKAVTLHDQGTTQWADLSS 114
           Y RQL + G      L+T+ V +      G EI KN+IL G+ + T+ D    Q  D+ +
Sbjct: 814 YDRQLRLWGDHGQSALETARVCLINATATGTEILKNVILPGIGSFTIVDGNKVQGEDVGN 635

Query: 115 QFYLREEDIGKNRAEVSQPRLAELNSYVPVTAYTGPLVE-----------DFLSSFQVVV 163
            F+L+ + IGK+RA+V+   L ELN  V     TG  VE           DF ++F +V+
Sbjct: 634 NFFLQVDSIGKSRAQVATELLGELNDDV-----TGNFVEENVENLLESNADFFTTFSIVI 470

Query: 164 LTNSPLEAQLRVGEFCHSRGIKLVVADTRGLFGQL 198
            TN   +  L++        I L+V    G  G L
Sbjct: 469 ATNLHEKTLLQLAGVLWENNIPLLVCRCYGFIGYL 365

 Score = 41.2 bits (95), Expect = 0.002,   Method: Composition-based stats.
 Identities = 23/96 (23%), Positives = 45/96 (46%)
 Frame = -1

Query: 445 LPRQNRYDGQVAVFGSDFQEKLSKQKYFLVGAGAIGCELLKNFAMIGLGCXXXXXXXXTD 504
           L + N+YD Q+ ++G   Q  L   +  L+ A A G E+LKN  + G+G          D
Sbjct: 832 LDKNNKYDRQLRLWGDHGQSALETARVCLINATATGTEILKNVILPGIG-----SFTIVD 668

Query: 505 MDTIEKSNLNRQFLFRPWDVTKLKSDTAAAAVRQMN 540
            + ++  ++   F  +   + K ++  A   + ++N
Sbjct: 667 GNKVQGEDVGNNFFLQVDSIGKSRAQVATELLGELN 560
>14935
          Length = 378

 Score = 36.2 bits (82), Expect = 0.066,   Method: Compositional matrix adjust.
 Identities = 20/62 (32%), Positives = 31/62 (50%), Gaps = 2/62 (3%)
 Frame = -2

Query: 614 LTESYSSSQDPPEKSIPICTLKNFPNAIEHTLQWARDEFEGLF--KQPAENVNQYLTDSK 671
           LTE Y       +KS P CT++N P+   H + WA+  F  LF  + P ++V+    D +
Sbjct: 377 LTECYECQPKAAQKSFPGCTIRNTPSEPIHCVVWAKHLFNQLFGEEDPDQDVSPDTEDPE 198

Query: 672 FV 673
             
Sbjct: 197 LT 192
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|149255275|ref|XP_893151.3| PREDICTED: similar to
electrogenic sodium bicarbonate cotransporter NBC4c isoform 3 [Mus
musculus]
         (1113 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

14939                                                                 202   1e-99
17976                                                                 177   6e-52
18083                                                                 129   8e-30
30765                                                                  37   0.042
>14939
          Length = 1186

 Score =  202 bits (513), Expect(2) = 1e-99,   Method: Compositional matrix adjust.
 Identities = 93/150 (62%), Positives = 111/150 (74%)
 Frame = -1

Query: 762  FPTKVRTLVADFSIVFSILLFCGIDACFGLQTPKLHVPSVIKPTRPDRGWFVAPFGKNPW 821
            FPT VR  ++DFS++ +IL     D C GL TPKLHVP    PT P RGW + P G+NPW
Sbjct: 1114 FPTMVRATLSDFSVLIAILSMVVFDICVGLPTPKLHVPETFAPTNPKRGWLINPVGENPW 935

Query: 822  WVYPASILPALLVTILIFMDQQITAVIVNRKENKLRKAAGYHLDLFWVGILMALCSFTGL 881
            W   A+++PALL  ILIFMDQQITAVIVNRKENKL K  GYHLDLF V +L+ LCSF GL
Sbjct: 934  WTTLAAVIPALLAVILIFMDQQITAVIVNRKENKLVKGRGYHLDLFIVSVLIILCSFLGL 755

Query: 882  PWYVAATVISIAHIDSLKMETETSAPGEQP 911
            PW+VAATV+SI H++SLK E++ SAP   P
Sbjct: 754  PWFVAATVLSINHVNSLKKESQCSAPANNP 665

 Score =  181 bits (459), Expect(2) = 1e-99,   Method: Compositional matrix adjust.
 Identities = 85/146 (58%), Positives = 110/146 (75%), Gaps = 1/146 (0%)
 Frame = -3

Query: 906  APGEQPQFLGVREQRVTGVMVFILTGISVFLAPILKYIPMPVLYGVFLYMGVASLNGIQF 965
             PGEQP+FLGVREQRVTG+ +F+L GISV L  +LK+IPMPVLYGVFLYMGV+SL G+Q 
Sbjct: 683  CPGEQPKFLGVREQRVTGITIFLLIGISVMLTSVLKFIPMPVLYGVFLYMGVSSLRGMQL 504

Query: 966  WERCKLFLMPAKHQPDHAFLRHVPLRRIHLFTLVQILCLALLWILKS-TMAAIIFPVMIL 1024
              R  ++ MPAK+Q D  FLRHV   R+HLFT++QI CL  LW +KS    +I FP+M+L
Sbjct: 503  VHRVLIWFMPAKYQWDLMFLRHVRTNRVHLFTIIQIFCLLCLWGIKSYKKISIAFPIMVL 324

Query: 1025 GLIIVRRLLDLIFSQHDLAWIDNILP 1050
             +  VR+ LD +F Q +L W+D+I+P
Sbjct: 323  AMCFVRKALDWVFDQRELKWLDDIMP 246
>17976
          Length = 781

 Score =  177 bits (448), Expect(2) = 6e-52,   Method: Compositional matrix adjust.
 Identities = 77/137 (56%), Positives = 112/137 (81%), Gaps = 1/137 (0%)
 Frame = +1

Query: 915  GVREQRVTGVMVFILTGISVFLAPILKYIPMPVLYGVFLYMGVASLNGIQFWERCKLFLM 974
            GVREQR+TG+MV +L+G++V    +LK+IPM VLYGVFLYMG+A+L G+QF +R  L L 
Sbjct: 139  GVREQRLTGLMVGLLSGLTVLFTAVLKFIPMAVLYGVFLYMGMAALKGMQFIDRILLMLK 318

Query: 975  PAKHQPDHAFLRHVPLRRIHLFTLVQILCLALLWILKSTMA-AIIFPVMILGLIIVRRLL 1033
            PAK+QPD  +LRHVP++R+H+FT +Q++CLA+LW++KS  + +IIFP+M+LG   VR+ L
Sbjct: 319  PAKYQPDTTYLRHVPIKRVHIFTAIQVVCLAVLWVIKSVKSVSIIFPIMVLGTCFVRKGL 498

Query: 1034 DLIFSQHDLAWIDNILP 1050
            D +F+Q +L W+D+I+P
Sbjct: 499  DYLFTQGELKWLDDIMP 549

 Score = 47.0 bits (110), Expect(2) = 6e-52,   Method: Composition-based stats.
 Identities = 24/37 (64%), Positives = 29/37 (78%), Gaps = 1/37 (2%)
 Frame = +3

Query: 880 GLPW-YVAATVISIAHIDSLKMETETSAPGEQPQFLG 915
           GLP   VAATV ++AHI SLK E+E +APGE+P FLG
Sbjct: 30  GLPLGTVAATVSALAHIMSLKKESECTAPGERPTFLG 140
>18083
          Length = 865

 Score =  129 bits (323), Expect = 8e-30,   Method: Composition-based stats.
 Identities = 81/217 (37%), Positives = 122/217 (56%), Gaps = 5/217 (2%)
 Frame = -3

Query: 836  ILIFMDQQITAVIVNRKENKLRKAAGYHLDLFWVGILMALCSFTGLPWYVAATVISIAHI 895
            +L FMDQ I+A +VN  +NK++K   YH DL  + ++ A+ S    P   AA   S  H+
Sbjct: 863  LLFFMDQNISAALVNAPQNKMKKGTAYHWDLLVIAVVNAVISVFAFPMVHAALPHSPLHV 684

Query: 896  DSLKMETETSAPGEQPQ-FLGVREQRVTGVMVFILTGISVFLAPILKYIPMPVLYGVFLY 954
             +L    E    G   Q  + VRE R+T ++  IL G+S+ +  +L YIP PVLYG+FLY
Sbjct: 683  RALADVEERVVQGHITQTVVRVRETRITAILSHILIGLSILIMFVLAYIPTPVLYGLFLY 504

Query: 955  MGVASLNGIQFWERCKLFLMPAKHQPDHAFLRHVPLRRIHLFTLVQILCLALLWILKSTM 1014
            + + +L   Q +ER  LF       P   ++RHVP R++H+FTL+Q+L L +L +     
Sbjct: 503  VAITALYDNQMFERITLFFTEQSAYPPTHYIRHVPQRKVHIFTLIQLLQLVVLCVFGFVS 324

Query: 1015 AA---IIFPVMILGLIIVRRL-LDLIFSQHDLAWIDN 1047
             A   + FPV+I  LI +R + +  I  Q  +A ID+
Sbjct: 323  FAYLKMFFPVLIFLLIPIRHMVIPKIVEQKYIAAIDH 213
>30765
          Length = 635

 Score = 37.0 bits (84), Expect = 0.042,   Method: Compositional matrix adjust.
 Identities = 27/98 (27%), Positives = 45/98 (45%), Gaps = 1/98 (1%)
 Frame = -3

Query: 134 WIKFEEKVEEGGERWSKPHVSTLSLHSLFELRTCLQTGTVLLDLDSCSL-PQIIDDVIEK 192
           WI     +      WSKP  ST ++HS    RT L TG + L   +CS+ P     ++  
Sbjct: 420 WISARLPLTRYSPSWSKPFFSTAAMHS----RTKLGTGALSLSHWACSVDPNTASLMMPC 253

Query: 193 QIEDGLLRPELRERVSYVLLRKHRHQTKKPIHRSLADI 230
            +    +   +R+  S +L+   R ++  P+   L+DI
Sbjct: 252 LMRSSWVGLRMRKLSSLLLMPAIRTRSAPPLSAPLSDI 139
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|19923869|ref|NP_612187.1| non-metastatic cells 7,
protein expressed in (nucleoside-diphosphate kinase) isoform 1 [Mus
musculus]
         (395 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

32935                                                                 191   1e-99
02656                                                                 162   2e-40
02733                                                                  81   2e-16
14087                                                                  35   3e-06
31902                                                                  46   2e-05
30332                                                                  31   1.1  
02658                                                                  29   3.6  
17453                                                                  28   4.3  
>32935
          Length = 1188

 Score =  191 bits (485), Expect(2) = 1e-99,   Method: Compositional matrix adjust.
 Identities = 93/150 (62%), Positives = 109/150 (72%), Gaps = 6/150 (4%)
 Frame = +1

Query: 251 NTAKFTNCTCCIIKPHAISEGMLGKNLIAIRDACFGMSAIQMFNLDRANVEEFYEVYKGV 310
           NTA   NCTCCIIKP A   G+ GK + AI +A F + + +MF L++AN EEF EVYKGV
Sbjct: 694 NTASIGNCTCCIIKPSAFKAGVAGKIINAITEAGFRVGSAEMFTLEKANAEEFLEVYKGV 873

Query: 311 VSEYNDMVTELCSGPCVAIEIQQSNPTK------TFREFCGPADPEIARHLRPETLRAIF 364
           V EY  MVTEL SGPC+A+EI   + T        FRE  GP DPEIARHLRP TLRA+F
Sbjct: 874 VHEYPAMVTELTSGPCLALEIVGGSGTNASLLAPAFRELAGPVDPEIARHLRPRTLRAMF 1053

Query: 365 GKTKVQNAVHCTDLPEDGLLEVQYFFKILD 394
           G  K++NAVHCTDLP+DG LEV+YFFKILD
Sbjct: 1054GTDKIKNAVHCTDLPDDGPLEVEYFFKILD 1143

 Score =  190 bits (483), Expect(2) = 1e-99,   Method: Compositional matrix adjust.
 Identities = 97/232 (41%), Positives = 144/232 (62%), Gaps = 6/232 (2%)
 Frame = +2

Query: 24  ERFAFIAEWYDPNASLLRRYELLFYP---VDGSV---EMHDVKNRRTFLKRTKYEDLRLE 77
           ER++FI EWYD  ++   R++  ++    V G V   E  DV   ++  +R +     L 
Sbjct: 11  ERYSFIVEWYDDMSARTLRFQFFYFTNSQVCGDVRHKEPQDVSANQSERQRAQ----SLR 178

Query: 78  DLFIGNKVNVFSRQLVLIDYGDQYTARQLGSRKEKTLALIKPDAVSKAGEIIEMINKSGF 137
            +          R L ++DY D+YT R+L S++E+TL LIKPDAV K G++++ I + GF
Sbjct: 179 PVHWQQHQPPAPRLLTIVDYDDEYTRRKLTSKRERTLGLIKPDAVEKLGQVLDKILQKGF 358

Query: 138 TITKLRMMTLTRKEAADFHVDHHSRPFYNELIQFITSGPVIAMEILRDDAICEWKRLLGP 197
            I++LRM  L R  A +F+ +H S+PF N L+ ++TSGPV+A EI+ ++A+  W+  +GP
Sbjct: 359 LISRLRMCKLDRNTALEFYQEHRSKPFLNALLDYVTSGPVVAFEIVGENAVGAWREAIGP 538

Query: 198 ANSGLSRTDAPGSIRALFGTDGVRNAAHGPDTFASAAREMELFFPSSGGCGP 249
            +  L+R +AP SIRA +GTD   NA HG D+  SAARE+E FFPSSG   P
Sbjct: 539 TDPSLARKEAPTSIRAQYGTDVTCNAVHGSDSPGSAAREVEFFFPSSGSHSP 694

 Score = 82.4 bits (202), Expect = 3e-16,   Method: Compositional matrix adjust.
 Identities = 49/132 (37%), Positives = 70/132 (53%)
 Frame = +2

Query: 259 TCCIIKPHAISEGMLGKNLIAIRDACFGMSAIQMFNLDRANVEEFYEVYKGVVSEYNDMV 318
           T  +IKP A+ +  LG+ L  I    F +S ++M  LDR    EFY+ ++      N ++
Sbjct: 284 TLGLIKPDAVEK--LGQVLDKILQKGFLISRLRMCKLDRNTALEFYQEHRSK-PFLNALL 454

Query: 319 TELCSGPCVAIEIQQSNPTKTFREFCGPADPEIARHLRPETLRAIFGKTKVQNAVHCTDL 378
             + SGP VA EI   N    +RE  GP DP +AR   P ++RA +G     NAVH +D 
Sbjct: 455 DYVTSGPVVAFEIVGENAVGAWREAIGPTDPSLARKEAPTSIRAQYGTDVTCNAVHGSDS 634

Query: 379 PEDGLLEVQYFF 390
           P     EV++FF
Sbjct: 635 PGSAAREVEFFF 670

 Score = 68.9 bits (167), Expect = 3e-12,   Method: Compositional matrix adjust.
 Identities = 46/142 (32%), Positives = 70/142 (49%), Gaps = 13/142 (9%)
 Frame = +1

Query: 113 TLALIKPDAVSK--AGEIIEMINKSGFTITKLRMMTLTRKEAADF-----HVDHHSRPFY 165
           T  +IKP A     AG+II  I ++GF +    M TL +  A +F      V H     Y
Sbjct: 718 TCCIIKPSAFKAGVAGKIINAITEAGFRVGSAEMFTLEKANAEEFLEVYKGVVHE----Y 885

Query: 166 NELIQFITSGPVIAMEILRDDAI------CEWKRLLGPANSGLSRTDAPGSIRALFGTDG 219
             ++  +TSGP +A+EI+             ++ L GP +  ++R   P ++RA+FGTD 
Sbjct: 886 PAMVTELTSGPCLALEIVGGSGTNASLLAPAFRELAGPVDPEIARHLRPRTLRAMFGTDK 1065

Query: 220 VRNAAHGPDTFASAAREMELFF 241
           ++NA H  D       E+E FF
Sbjct: 1066IKNAVHCTDLPDDGPLEVEYFF 1131
>02656
          Length = 2642

 Score =  162 bits (411), Expect = 2e-40,   Method: Compositional matrix adjust.
 Identities = 95/288 (32%), Positives = 154/288 (53%), Gaps = 4/288 (1%)
 Frame = +3

Query: 111 EKTLALIKPDAVSKAGE-IIEMINKSGFTITKLRMMTLTRKEAADFHVDHHSRPFYNELI 169
           ++TLALI+PDA +   + I+E I ++GF I   + ++LT+++A +F+ +H  +P+Y+EL 
Sbjct: 669 QRTLALIRPDAFANNKDAILEKIKEAGFQIALHKEVSLTKEQAEEFYKEHAGQPYYDELT 848

Query: 170 QFITSGPVIAMEILRDDAICEWKRLLGPANSGLSRTDAPGSIRALFGTDGVR-NAAHGPD 228
             ++SGP++A+ + R+DA+  W+ +LGP +   ++T AP  +RA F  D    N  HG D
Sbjct: 849 DRMSSGPLLALGLAREDAVENWREMLGPTDVEEAKTAAPDCLRAQFAVDSTAINQLHGSD 1028

Query: 229 TFASAAREMELFFPSSGGCGPANTAKFTNCTCCIIKPHAISEGMLGKNLI--AIRDACFG 286
           +  SA +E+E FFP                T  +IKP    +G   K+ I   I  A F 
Sbjct: 1029STQSAKKELEFFFP-------------VEQTVAMIKP----DGYGTKDAIIEKIHQAGFR 1157

Query: 287 MSAIQMFNLDRANVEEFYEVYKGVVSEYNDMVTELCSGPCVAIEIQQSNPTKTFREFCGP 346
           ++A +   + R   E FY+  K     Y  +V  + SGP + + + +      +RE  GP
Sbjct: 1158IAARKETTITRDIAESFYDDQKD-KDYYESLVEHMTSGPTMFMVLSREGAVDGWREEIGP 1334

Query: 347 ADPEIARHLRPETLRAIFGKTKVQNAVHCTDLPEDGLLEVQYFFKILD 394
            DP  A+   P +LRA FG   +QNAVH     E+   +++  F  LD
Sbjct: 1335TDPTKAKEQNPNSLRAQFGTDVLQNAVHGASSSEEAKKKIKAVFGDLD 1478

 Score =  141 bits (356), Expect = 4e-34,   Method: Compositional matrix adjust.
 Identities = 85/289 (29%), Positives = 148/289 (51%), Gaps = 9/289 (3%)
 Frame = +3

Query: 113 TLALIKPDAVS--KAGEIIEMINKSGFTITKLRMMTLTRKEAADFHVDHHSRPFYNELIQ 170
           T+A+IKP+ V+  K  EI+  +   G  +       LT  EA +F+       ++ +L+ 
Sbjct: 219 TVAIIKPNVVANGKVDEILAEMKARGINVKAQEERQLTEDEAREFYSHLQGEEYFEDLVA 398

Query: 171 FITSGP---VIAMEILRDDAIC-EWKRLLGPANSGLSRTDAPGSIRALFGTDGVRNAAHG 226
           F+ SGP   ++  E   DD++  +W+ +LGP     ++  AP S+RA +G  G+ NA HG
Sbjct: 399 FMASGPSHVLVLTEGQEDDSVVKDWRDMLGPPTVEDAKEQAPESLRARYGQGGLMNAVHG 578

Query: 227 PDTFASAAREMELFFPSSGGCGPANTAKFTNCTCCIIKPHAISEGMLGKNLI--AIRDAC 284
            D+  +AARE+  FFP           K    T  +I+P A +     K+ I   I++A 
Sbjct: 579 SDSKETAARELAFFFPHMQAPKLQKKKKEVQRTLALIRPDAFAN---NKDAILEKIKEAG 749

Query: 285 FGMSAIQMFNLDRANVEEFYEVYKGVVSEYNDMVTELCSGPCVAIEIQQSNPTKTFREFC 344
           F ++  +  +L +   EEFY+ + G    Y+++   + SGP +A+ + + +  + +RE  
Sbjct: 750 FQIALHKEVSLTKEQAEEFYKEHAGQPY-YDELTDRMSSGPLLALGLAREDAVENWREML 926

Query: 345 GPADPEIARHLRPETLRAIFG-KTKVQNAVHCTDLPEDGLLEVQYFFKI 392
           GP D E A+   P+ LRA F   +   N +H +D  +    E+++FF +
Sbjct: 927 GPTDVEEAKTAAPDCLRAQFAVDSTAINQLHGSDSTQSAKKELEFFFPV 1073
>02733
          Length = 853

 Score = 80.9 bits (198), Expect(2) = 2e-16,   Method: Compositional matrix adjust.
 Identities = 36/110 (32%), Positives = 64/110 (58%)
 Frame = -1

Query: 132 INKSGFTITKLRMMTLTRKEAADFHVDHHSRPFYNELIQFITSGPVIAMEILRDDAICEW 191
           I+++GF I   +  T+TR  A  F+ D   + +Y  L++ +TSGP + M + R+ A+  W
Sbjct: 742 IHQAGFRIAARKETTITRDIAESFYDDQKDKDYYESLVEHMTSGPTMFMVLSREGAVDGW 563

Query: 192 KRLLGPANSGLSRTDAPGSIRALFGTDGVRNAAHGPDTFASAAREMELFF 241
           +  +GP +   ++   P S+RA FGTD ++NA HG  +   A ++++  F
Sbjct: 562 REEIGPTDPTKAKEQNPNSLRAQFGTDVLQNAVHGASSSEEAKKKIKAVF 413

 Score = 22.3 bits (46), Expect(2) = 2e-16,   Method: Compositional matrix adjust.
 Identities = 9/19 (47%), Positives = 14/19 (73%)
 Frame = -2

Query: 111 EKTLALIKPDAVSKAGEII 129
           ++TLALI+PDA +   + I
Sbjct: 807 QRTLALIRPDAFANNKDAI 751

 Score = 59.3 bits (142), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 36/115 (31%), Positives = 55/115 (47%)
 Frame = -1

Query: 280 IRDACFGMSAIQMFNLDRANVEEFYEVYKGVVSEYNDMVTELCSGPCVAIEIQQSNPTKT 339
           I  A F ++A +   + R   E FY+  K     Y  +V  + SGP + + + +      
Sbjct: 742 IHQAGFRIAARKETTITRDIAESFYDDQKDK-DYYESLVEHMTSGPTMFMVLSREGAVDG 566

Query: 340 FREFCGPADPEIARHLRPETLRAIFGKTKVQNAVHCTDLPEDGLLEVQYFFKILD 394
           +RE  GP DP  A+   P +LRA FG   +QNAVH     E+   +++  F  LD
Sbjct: 565 WREEIGPTDPTKAKEQNPNSLRAQFGTDVLQNAVHGASSSEEAKKKIKAVFGDLD 401
>14087
          Length = 2025

 Score = 35.0 bits (79), Expect(2) = 3e-06,   Method: Compositional matrix adjust.
 Identities = 12/36 (33%), Positives = 23/36 (63%)
 Frame = +2

Query: 164 FYNELIQFITSGPVIAMEILRDDAICEWKRLLGPAN 199
           +Y  L++ +TSGP + M + R+ A+  W+  +GP +
Sbjct: 2   YYESLVEHMTSGPTMFMVLSREGAVDGWREEIGPTD 109

 Score = 33.5 bits (75), Expect(2) = 3e-06,   Method: Compositional matrix adjust.
 Identities = 14/34 (41%), Positives = 22/34 (64%)
 Frame = +3

Query: 208 PGSIRALFGTDGVRNAAHGPDTFASAAREMELFF 241
           P S+RA FGTD ++NA HG  +   A ++++  F
Sbjct: 135 PNSLRAQFGTDVLQNAVHGASSSEEAKKKIKAVF 236

 Score = 33.9 bits (76), Expect(2) = 1e-04,   Method: Compositional matrix adjust.
 Identities = 16/43 (37%), Positives = 23/43 (53%)
 Frame = +3

Query: 352 ARHLRPETLRAIFGKTKVQNAVHCTDLPEDGLLEVQYFFKILD 394
           A+   P +LRA FG   +QNAVH     E+   +++  F  LD
Sbjct: 120 AKEQNPNSLRAQFGTDVLQNAVHGASSSEEAKKKIKAVFGDLD 248

 Score = 28.9 bits (63), Expect(2) = 1e-04,   Method: Compositional matrix adjust.
 Identities = 11/36 (30%), Positives = 18/36 (50%)
 Frame = +2

Query: 314 YNDMVTELCSGPCVAIEIQQSNPTKTFREFCGPADP 349
           Y  +V  + SGP + + + +      +RE  GP DP
Sbjct: 5   YESLVEHMTSGPTMFMVLSREGAVDGWREEIGPTDP 112
>31902
          Length = 546

 Score = 46.2 bits (108), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 21/52 (40%), Positives = 30/52 (57%)
 Frame = +1

Query: 191 WKRLLGPANSGLSRTDAPGSIRALFGTDGVRNAAHGPDTFASAAREMELFFP 242
           W+  +GP +  L+R +AP SIRA +GTD   NA HG D+  +    + L  P
Sbjct: 388 WREAIGPTDPSLARKEAPTSIRAQYGTDVTCNAVHGSDSPGNWPVPLTLRLP 543

 Score = 44.3 bits (103), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 26/74 (35%), Positives = 35/74 (47%)
 Frame = +1

Query: 306 VYKGVVSEYNDMVTELCSGPCVAIEIQQSNPTKTFREFCGPADPEIARHLRPETLRAIFG 365
           + KG  S +N  +T  C     A     S     +RE  GP DP +AR   P ++RA +G
Sbjct: 292 MMKGTASSWNGTMT--CQHAPCASSSSTSPTPSLWREAIGPTDPSLARKEAPTSIRAQYG 465

Query: 366 KTKVQNAVHCTDLP 379
                NAVH +D P
Sbjct: 466 TDVTCNAVHGSDSP 507

 Score = 33.1 bits (74), Expect = 0.22,   Method: Compositional matrix adjust.
 Identities = 12/32 (37%), Positives = 20/32 (62%)
 Frame = +3

Query: 24  ERFAFIAEWYDPNASLLRRYELLFYPVDGSVE 55
           ER++FI EWYD  ++   R++  ++    SVE
Sbjct: 297 ERYSFIVEWYDDMSARTLRFQFFYFTNSKSVE 392
>30332
          Length = 401

 Score = 30.8 bits (68), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 28/96 (29%), Positives = 34/96 (35%), Gaps = 19/96 (19%)
 Frame = +1

Query: 196 GPANSGLSRTDAPGSIRALFGTD------GVRNAAHGPDTFASAAR-EMELFFPSSGGCG 248
           GPA +G S T+ PG+     GT       G R   H               F  SSGG G
Sbjct: 4   GPAGTGQS*TEGPGAQTKQTGTSPERYQPGDRQEGHRVQGLGQQGEGRTTKFAKSSGGLG 183

Query: 249 PANTAKFTNC------------TCCIIKPHAISEGM 272
             +T +  NC            T C  +PH  S G 
Sbjct: 184 ALHTKREGNCGRTARQRGYTRQTSCRDRPHERSGGQ 291
>02658
          Length = 1185

 Score = 28.9 bits (63), Expect = 3.6,   Method: Compositional matrix adjust.
 Identities = 16/47 (34%), Positives = 24/47 (51%)
 Frame = +1

Query: 200 SGLSRTDAPGSIRALFGTDGVRNAAHGPDTFASAAREMELFFPSSGG 246
           SG  RTD  G   +LFG+DG ++   G  T    +R +++     GG
Sbjct: 139 SGFGRTDTLGCGGSLFGSDGNQSVHGGDKTARPGSRVLQICGGHYGG 279
>17453
          Length = 469

 Score = 28.5 bits (62), Expect = 4.3,   Method: Compositional matrix adjust.
 Identities = 17/60 (28%), Positives = 28/60 (46%), Gaps = 5/60 (8%)
 Frame = +3

Query: 217 TDGVRNAAHGPDTFASAAREMELFF-----PSSGGCGPANTAKFTNCTCCIIKPHAISEG 271
           T  V+ ++  P   ++   ++ LF      PSSG    +NTA F +     +KP  I +G
Sbjct: 6   TPSVKKSSFQPSVSSATKSKLSLFSAPEPGPSSGESSQSNTASFLHNKLDFLKPDKIRDG 185
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|46049022|ref|NP_079826.2| proteasome, 26S, non-ATPase
regulatory subunit 6 [Mus musculus]
         (389 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

18013                                                                 359   1e-99
>18013
          Length = 1013

 Score =  359 bits (921), Expect = 1e-99,   Method: Compositional matrix adjust.
 Identities = 173/217 (79%), Positives = 191/217 (88%)
 Frame = +1

Query: 173 DWDRRNRLKVYQGLYCVAIRDFKQAAELFLDTVSTFTSYELMDYKTFVTYTVYVSMIALE 232
           DWDRRNRLKVY+G+YC++IR FK+AA LFLDT++TFTSYELMDY  FVTYTV  S+IALE
Sbjct: 1   DWDRRNRLKVYRGVYCMSIRQFKEAATLFLDTIATFTSYELMDYPQFVTYTVICSVIALE 180

Query: 233 RPDLREKVIKGAEILEVLHSLPAVRQYLFSLYECRYSVFFQSLAIVEQEMKKDWLFAPHY 292
           RP LREKV KG+EILEVLH LP V++YLFSLY+C YS FF SLA VE+ M+ D L A HY
Sbjct: 181 RPKLREKVTKGSEILEVLHGLPKVKRYLFSLYDCHYSEFFLSLAEVEEMMQTDRLMAAHY 360

Query: 293 RYYVREMRIHAYSQLLESYRSLTLGYMAEAFGVGVDFIDQELSRFIAAGRLHCKIDKVNE 352
           RYYVREMRI AY+QLLESYRSLTL YMA+AFGV VDFIDQELSRFIAAGRLHCKIDKV  
Sbjct: 361 RYYVREMRIMAYAQLLESYRSLTLDYMADAFGVTVDFIDQELSRFIAAGRLHCKIDKVGG 540

Query: 353 IVETNRPDSKNWQYQETIKKGDLLLNRVQKLSRVINM 389
           IVETNRPDSKNWQYQ TIK GD+LLNRVQKLSRVIN+
Sbjct: 541 IVETNRPDSKNWQYQSTIKHGDILLNRVQKLSRVINI 651
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|28076969|ref|NP_081905.1| phosphoglucomutase 2-like 1
[Mus musculus]
         (621 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

27797                                                                 359   2e-99
04593                                                                  29   5.1  
25536                                                                  28   10.0 
>27797
          Length = 1266

 Score =  359 bits (922), Expect = 2e-99,   Method: Compositional matrix adjust.
 Identities = 186/395 (47%), Positives = 256/395 (64%), Gaps = 1/395 (0%)
 Frame = -2

Query: 206  IEECVEPWNDSWNDNLVDTSPLKKDPLQDICKKYMEDLKKICFYRDLNSKTTLKFVHTSF 265
             +E + P   SW+ +++   PL KDP  ++ +KY    K +C++R+ NS ++L+ V+T+ 
Sbjct: 1226 FQENLVPVASSWDVSILKDHPLCKDPYAEVLEKYNAAAKVLCYHRENNSSSSLRVVYTAM 1047

Query: 266  HGVG-HDYVQLAFQVFGFKPPIPVPEQKDPDPDFSTVKCPNPEEGESVLELSLRLAEKEN 324
            HG G     +   +   F     +  + +    F        +EG   L LS++ A+  N
Sbjct: 1046 HGGGLTPMCRSVSKPSAFICQCQLNNRLNQIRSFPL*FTLILKEGRG-LALSMKKADDTN 870

Query: 325  ARIVLATDPDADRLAVAELQENGRWKVFTGNELAALFGWWMFDCWKKNKPNADVKNVYML 384
              +++A DPDADRLAVAE   NG WK+FTGNEL AL G+W++  +++  P+    +VYML
Sbjct: 869  CPVIVANDPDADRLAVAEKLPNGEWKIFTGNELGALLGYWLWTSFRQQNPDVPGTDVYML 690

Query: 385  ATTVSSKILKAIALKEGFHFEETLPGFKWIGSRIKDLLGNGKEVLFAFEESIGFLCGTSV 444
            A+TVSSKIL+ +AL EGF FEETL GFKW+G+R  +L   GK VLFAFEE+IGF+CG++V
Sbjct: 689  ASTVSSKILQTMALMEGFKFEETLTGFKWMGNRTAELQKMGKTVLFAFEEAIGFMCGSNV 510

Query: 445  LDKDGXXXXXXXXEMASFLDTRKVTLMEQLTKVYEIYGYHMSKTSYFLCYDPPTIKTIFE 504
            LDKDG        E AS L  +  TL +QLT +Y  YGYH+S  SY++C DP TI+ +F 
Sbjct: 509  LDKDGVTAAAVITEFASRLYAQNSTLEKQLTAIYSKYGYHLSSNSYYICNDPATIQRMFT 330

Query: 505  RIRNFESPKEYPKFCGAFAILHVRDITTGYDSSQPNKKSVLPVSKNSQMITFTFQNGCVA 564
             +R      +YPK CG++ I  VRD+T GYDSSQP+ K +LPVSK+SQMITFTF+NGCVA
Sbjct: 329  ELRKCGGENKYPKACGSYKISGVRDLTVGYDSSQPDNKPLLPVSKSSQMITFTFENGCVA 150

Query: 565  TLRTSGTEPKIKYYAEMCASPGQSDTTFLEEELKK 599
            TLRTSGTEPKIKYY E    P ++   ++E E  K
Sbjct: 149  TLRTSGTEPKIKYYTEHRPDPSKN---WIEREQNK 54
>04593
          Length = 1639

 Score = 29.3 bits (64), Expect = 5.1,   Method: Compositional matrix adjust.
 Identities = 12/24 (50%), Positives = 17/24 (70%)
 Frame = +2

Query: 328 VLATDPDADRLAVAELQENGRWKV 351
           V +TDPD + LAVA++ E   WK+
Sbjct: 206 VTSTDPDVNILAVADVMETRGWKI 277
>25536
          Length = 486

 Score = 28.1 bits (61), Expect = 10.0,   Method: Compositional matrix adjust.
 Identities = 20/70 (28%), Positives = 34/70 (48%)
 Frame = +1

Query: 215 DSWNDNLVDTSPLKKDPLQDICKKYMEDLKKICFYRDLNSKTTLKFVHTSFHGVGHDYVQ 274
           D W + L D   L ++ ++ +C+K  E L K    +++    T   V    HG  HD ++
Sbjct: 73  DQWIEQLNDCKQLSENQVKTLCEKAKEILSKESNVQEVKCPVT---VCGDVHGQFHDLME 243

Query: 275 LAFQVFGFKP 284
           L F++ G  P
Sbjct: 244 L-FRIGGKSP 270
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|29825827|ref|NP_821170.1| vacuolar protein sorting 26
homolog B [Mus musculus]
         (336 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

01953                                                                 357   4e-99
01034                                                                 266   9e-72
13123                                                                  67   1e-11
05131                                                                  47   9e-06
11860                                                                  32   0.51 
>01953
          Length = 1732

 Score =  357 bits (916), Expect = 4e-99,   Method: Compositional matrix adjust.
 Identities = 169/222 (76%), Positives = 195/222 (87%), Gaps = 5/222 (2%)
 Frame = -2

Query: 98   EITQSQAFDFEFTHVEKPYESYTGQNVKLRYFLRATISRRLNDVVKEMDIVVHTLSTYPE 157
            ++T +Q++ FEF  VEKPYESYTG NV+LRYFLR TI +R++DVVKE DIVVHTLS YP+
Sbjct: 1731 DLTHNQSYPFEFQQVEKPYESYTGANVRLRYFLRVTIVKRISDVVKEQDIVVHTLSQYPD 1552

Query: 158  LNSSIKMEVGIEDCLHIEFEYNKSKYHLKDVIVGKIYFLLVRIKIKHMEIDIIKRETTGT 217
            +N+SIKMEVGIEDCLHIEFEYNKSKYHLKDVIVGKIYFLLVRIKIKHME+ +IKRETTGT
Sbjct: 1551 MNNSIKMEVGIEDCLHIEFEYNKSKYHLKDVIVGKIYFLLVRIKIKHMELQVIKRETTGT 1372

Query: 218  GPNVYHENDTIAKYEIMDGAPVRGESIPIRLFLAGYELTPTMRDINKKFSVRYYLNLVLI 277
            GPN ++EN+TIAKYEIMDGAPVRGESIPIRLFL+GYELTP+MRDINKKFSV+YYLNLVL+
Sbjct: 1371 GPNTFNENETIAKYEIMDGAPVRGESIPIRLFLSGYELTPSMRDINKKFSVKYYLNLVLV 1192

Query: 278  DEEERRYFKQQEVVLWRKGDIVRKSMS-----HQAAIASQRF 314
            DEEERRYFKQQE++++RK D  RK+       HQ     Q F
Sbjct: 1191 DEEERRYFKQQEIIIFRKADXQRKNYQMALQHHQPVNPPQGF 1066
>01034
          Length = 522

 Score =  266 bits (680), Expect = 9e-72,   Method: Compositional matrix adjust.
 Identities = 122/154 (79%), Positives = 141/154 (91%)
 Frame = -1

Query: 67  KIEFIGQIELYYDRGNHHEFVSLVKDLARPGEITQSQAFDFEFTHVEKPYESYTGQNVKL 126
           K+EFIGQIELYYDRGNHHEF SLVK+LARPG++T +Q++ FEF  VEKPYESYTG NV+L
Sbjct: 465 KVEFIGQIELYYDRGNHHEFTSLVKELARPGDLTHNQSYPFEFQQVEKPYESYTGANVRL 286

Query: 127 RYFLRATISRRLNDVVKEMDIVVHTLSTYPELNSSIKMEVGIEDCLHIEFEYNKSKYHLK 186
           RYFLR TI +R++DVVKE DIVVHTLS YP++N+SIKMEVGIEDCLHIEFEYNKSKYHLK
Sbjct: 285 RYFLRVTIVKRISDVVKEQDIVVHTLSQYPDMNNSIKMEVGIEDCLHIEFEYNKSKYHLK 106

Query: 187 DVIVGKIYFLLVRIKIKHMEIDIIKRETTGTGPN 220
           D IVGKIYFLLVRIKI++ME+ I++RETTG GPN
Sbjct: 105 DAIVGKIYFLLVRIKIRYMELAIVRRETTGAGPN 4
>13123
          Length = 523

 Score = 66.6 bits (161), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 28/49 (57%), Positives = 39/49 (79%)
 Frame = +3

Query: 174 IEFEYNKSKYHLKDVIVGKIYFLLVRIKIKHMEIDIIKRETTGTGPNVY 222
           + + +  ++YHLKD IVGKIYFLLVRIKI++ME+ I++RETTG G   +
Sbjct: 186 LTWSWWTARYHLKDAIVGKIYFLLVRIKIRYMELAIVRRETTGAGTAAW 332
>05131
          Length = 864

 Score = 47.4 bits (111), Expect = 9e-06,   Method: Compositional matrix adjust.
 Identities = 42/183 (22%), Positives = 73/183 (39%), Gaps = 19/183 (10%)
 Frame = +1

Query: 107 FEFTHVEKP----YESYTGQNVKLRYFLRATISRRL--NDVVKEMDIVVH---------- 150
           FE     KP    YE+Y G  V ++Y +R  + R L   D+ K+ + ++           
Sbjct: 31  FEVPLKPKPGKTLYETYHGVFVNIQYMIRVEMKRSLLNKDLQKQCEFIIEYKSQEEKAKP 210

Query: 151 ---TLSTYPELNSSIKMEVGIEDCLHIEFEYNKSKYHLKDVIVGKIYFLLVRIKIKHMEI 207
                S  PE  + +K +  I     ++ +   S   + D + G++      + +K +EI
Sbjct: 211 KPVNFSISPETLAGVKEKQNIPK-FKVKGKLESSCVKITDPLKGELVLEHCEVPVKSIEI 387

Query: 208 DIIKRETTGTGPNVYHENDTIAKYEIMDGAPVRGESIPIRLFLAGYELTPTMRDINKKFS 267
            +++ ET G       +   I   +I DG   R  +IPI +        PT+   N K  
Sbjct: 388 QMVRVETCGCAEGYAKDATEIQNIQIADGDVCRNLAIPIYMIFPRLFTCPTLSTNNFKIG 567

Query: 268 VRY 270
             Y
Sbjct: 568 DTY 576
>11860
          Length = 944

 Score = 31.6 bits (70), Expect = 0.51,   Method: Compositional matrix adjust.
 Identities = 29/121 (23%), Positives = 46/121 (38%), Gaps = 25/121 (20%)
 Frame = +3

Query: 70  FIGQIELYYDRGN-----------HHEFVSLVKDLARPGEITQSQAFDFEFTHVEKPYES 118
           FI + E+YY R             HH+F  L KD+  P    Q Q F   F    K  + 
Sbjct: 192 FINEKEVYYLRALGDDPRKDIADIHHQFPELAKDITFPDFFEQDQFFSSVFRIASKGLQL 371

Query: 119 YTGQNVKLRYFLRATISRRL--------------NDVVKEMDIVVHTLSTYPELNSSIKM 164
           +T  +V     ++ T  +R+               D    +DI    L+ +P    +++M
Sbjct: 372 WTHYDVMDNLLIQVTGKKRVVLFSPQDAEKLYLQGDKSSVLDIDNPDLTRFPLFARAVRM 551

Query: 165 E 165
           E
Sbjct: 552 E 554
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|41054806|ref|NP_032164.2| guanine nucleotide binding
protein (G protein), alpha inhibiting 2 [Mus musculus]
         (355 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

11965                                                                 357   6e-99
13527                                                                 267   4e-72
29196                                                                 140   1e-33
20516                                                                 114   5e-26
34094                                                                  70   1e-12
09827                                                                  49   4e-06
08153                                                                  48   5e-06
10862                                                                  45   3e-05
18949                                                                  40   0.001
11378                                                                  38   0.006
18208                                                                  31   0.61 
08297                                                                  30   2.0  
01191                                                                  29   3.7  
01021                                                                  27   8.7  
>11965
          Length = 3256

 Score =  357 bits (915), Expect = 6e-99,   Method: Compositional matrix adjust.
 Identities = 167/222 (75%), Positives = 189/222 (85%)
 Frame = +1

Query: 134 DHGVQACFGRSREYQLNDSAAYYLNDLERIAQSDYIPTQQDVLRTRVKTTGIVETHFTFK 193
           D GVQ CF RS EYQLNDSA Y+L+DL+R+   DY+PT+QD+LRTRVKTTGIVE HF+FK
Sbjct: 1   DSGVQDCFSRSNEYQLNDSAKYFLDDLDRLGTKDYMPTEQDILRTRVKTTGIVEVHFSFK 180

Query: 194 DLHFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSAYDLVLAEDEEMNRMHESMKLFDS 253
           +L+FK+FDVGGQRSERKKWIHCFE VTAIIFCVA+S YD VL EDE  NRM ES+KLFDS
Sbjct: 181 NLNFKLFDVGGQRSERKKWIHCFEDVTAIIFCVAMSEYDQVLHEDETTNRMQESLKLFDS 360

Query: 254 ICNNKWFTDTSIILFLNKKDLFEEKITQSSLTICFPEYTGANKYDEAASYIQSKFEDLNK 313
           ICNNKWFTDTSIILFLNKKDLFEEKI +S LT+CFPEYTG   Y+E A+YIQ++FE  NK
Sbjct: 361 ICNNKWFTDTSIILFLNKKDLFEEKIKKSPLTVCFPEYTGKQTYEEVAAYIQAQFEAKNK 540

Query: 314 RKDTKEIYTHFTCATDTKNVQFVFDAVTDVIIKNNLKDCGLF 355
               KEIY H TCATDT N+QFVFDAVTDVII NNL+ CGL+
Sbjct: 541 SSQ-KEIYCHQTCATDTNNIQFVFDAVTDVIIANNLRGCGLY 663
>13527
          Length = 1091

 Score =  267 bits (683), Expect = 4e-72,   Method: Compositional matrix adjust.
 Identities = 123/198 (62%), Positives = 158/198 (79%)
 Frame = -2

Query: 1    MGCTVSAEDKAAAERSKMIDKNLREDGEKAAREVKLLLLGAGESGKSTIVKQMKIIHEDG 60
            MGCT+SAE++AA ERSK I+KNL+EDG +AA+++KLLLLGAGESGKSTIVKQMKIIHE G
Sbjct: 1042 MGCTLSAEERAAMERSKAIEKNLKEDGMQAAKDIKLLLLGAGESGKSTIVKQMKIIHEGG 863

Query: 61   YSEEECRQYRAVVYSNTIQSIMAIVKAMGNLQIDFADPQRADDARQLFALSCAAEEQGML 120
            ++ E+ +QYR VV+SNTIQS++AI++AMG L I F D +R  DA+ +  +    E+    
Sbjct: 862  FTSEDNKQYRPVVFSNTIQSLVAIIRAMGTLSIPFGDNERESDAKMVLDVIARMEDTEPF 683

Query: 121  PEDLSGVIRRLWADHGVQACFGRSREYQLNDSAAYYLNDLERIAQSDYIPTQQDVLRTRV 180
             E+L   + RLW D GVQ CF RS EYQLNDSA Y+L+DL+R+   DY+PT+QD+LRTRV
Sbjct: 682  SEELLAAMERLWMDSGVQDCFSRSNEYQLNDSAKYFLDDLDRLGTKDYMPTEQDILRTRV 503

Query: 181  KTTGIVETHFTFKDLHFK 198
            KTTGIVE HF+FK+L+FK
Sbjct: 502  KTTGIVEVHFSFKNLNFK 449
>29196
          Length = 431

 Score =  140 bits (352), Expect = 1e-33,   Method: Compositional matrix adjust.
 Identities = 79/146 (54%), Positives = 95/146 (65%), Gaps = 3/146 (2%)
 Frame = -2

Query: 126 GVIRRLWADHGVQACFGRSRE-YQLNDSAAYYLNDLERIAQSDYIPTQQDVLRTRVKTTG 184
             ++RLW D GVQ C   SR     N +    ++ +  I  +  I +Q +      ++  
Sbjct: 430 AAMKRLWLDSGVQEC---SRAATNTN*TIPLNISWMI*IG*ALRITSQPNRTFCAPESRP 260

Query: 185 IVETHF--TFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSAYDLVLAEDEEMN 242
                F    K+L+FK+FDVGGQRSERKKWIHCFE VTAIIFCVA+S YD VL EDE  N
Sbjct: 259 PAL*RFISPLKNLNFKLFDVGGQRSERKKWIHCFEDVTAIIFCVAMSEYDQVLHEDETTN 80

Query: 243 RMHESMKLFDSICNNKWFTDTSIILF 268
           RM ES+KLFDSICNNKWFTDTSIILF
Sbjct: 79  RMQESLKLFDSICNNKWFTDTSIILF 2
>20516
          Length = 534

 Score =  114 bits (286), Expect = 5e-26,   Method: Compositional matrix adjust.
 Identities = 64/161 (39%), Positives = 96/161 (59%), Gaps = 1/161 (0%)
 Frame = +2

Query: 191 TFKDLHFKMFDV-GGQRSERKKWIHCFEGVTAIIFCVALSAYDLVLAEDEEMNRMHESMK 249
           TF+++ F + +V GGQRS+R+KW  CF G+T+I+F  A S +D VL ED + NR+ ES  
Sbjct: 41  TFRNIFFLVGEVTGGQRSQRQKWYQCFVGITSILFLAASSEFDQVLMEDRKTNRLQESCD 220

Query: 250 LFDSICNNKWFTDTSIILFLNKKDLFEEKITQSSLTICFPEYTGANKYDEAASYIQSKFE 309
           +F++I NNK F+  SIILFLNK DL ++K     L   F  ++G ++    +  I +   
Sbjct: 221 IFETIINNKSFSGVSIILFLNKMDLLQDKN*ACQLRRLFSRFSG*SQGH*CSQSI*ASAV 400

Query: 310 DLNKRKDTKEIYTHFTCATDTKNVQFVFDAVTDVIIKNNLK 350
                   +    HFT A DT+N++ VF  V D I+ +NL+
Sbjct: 401 *FAPT*SKQTFVHHFTTAIDTENIKHVFQDVKDTILHDNLR 523
>34094
          Length = 452

 Score = 70.1 bits (170), Expect = 1e-12,   Method: Compositional matrix adjust.
 Identities = 30/48 (62%), Positives = 38/48 (79%)
 Frame = +1

Query: 54  KIIHEDGYSEEECRQYRAVVYSNTIQSIMAIVKAMGNLQIDFADPQRA 101
           +IIHE GYS+EEC QY+ VVYSN IQS++AIV+AM  L ++F  P RA
Sbjct: 103 RIIHEKGYSQEECLQYKPVVYSNAIQSMIAIVRAMNLLSVEFGHPDRA 246
>09827
          Length = 1201

 Score = 48.5 bits (114), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 43/162 (26%), Positives = 67/162 (41%), Gaps = 12/162 (7%)
 Frame = -3

Query: 178  TRVKTTGIVETHFTFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSAYDLVLAE 237
            T + T G       +K++ F ++DVGGQ   R  W H F+    +IF V  +  + V   
Sbjct: 1034 TTIPTIGFNVETVEYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDKERVQEA 855

Query: 238  DEEMNRMHESMKLFDSICNNKWFTDTSIILFLNKKDLFEEKITQSSLTICFPEYTGANKY 297
             EE+ RM    +L D++          +++F NK+DL       +  T    E  G +  
Sbjct: 854  REELTRMLNEDELRDAV----------LLVFANKQDL-----PHAMATAEITEKLGLHGL 720

Query: 298  DEAASYIQSK--------FEDL----NKRKDTKEIYTHFTCA 327
                 YIQS         +E L    N+ K+ K  +T   C 
Sbjct: 719  RNRTWYIQSTCATTGDGLYEGLDWLSNQLKNNKS*WTCLLCP 594
>08153
          Length = 1703

 Score = 48.1 bits (113), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 30/97 (30%), Positives = 46/97 (47%)
 Frame = +1

Query: 178 TRVKTTGIVETHFTFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSAYDLVLAE 237
           T + T G       +K++ F ++DVGGQ   R  W H F+    +IF V  +  + +   
Sbjct: 163 TTIPTIGFNVETVEYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERINEA 342

Query: 238 DEEMNRMHESMKLFDSICNNKWFTDTSIILFLNKKDL 274
            EE+ RM     L D+I          I++F NK+DL
Sbjct: 343 KEELARMLNEDDLRDAI----------ILVFANKQDL 423
>10862
          Length = 2896

 Score = 45.4 bits (106), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 25/83 (30%), Positives = 41/83 (49%)
 Frame = -3

Query: 192  FKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSAYDLVLAEDEEMNRMHESMKLF 251
             ++  F ++DVGGQ   R  W H + G   +IF V  +  D +    +E++R        
Sbjct: 2495 LQECQFNVWDVGGQDKIRPLWRHYYTGTQGLIFVVDCADRDRIDEARQELHR-------- 2340

Query: 252  DSICNNKWFTDTSIILFLNKKDL 274
              I N++   D  I++F NK+DL
Sbjct: 2339 --IINDREMRDAIILIFANKQDL 2277
>18949
          Length = 414

 Score = 40.4 bits (93), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 23/94 (24%), Positives = 40/94 (42%), Gaps = 1/94 (1%)
 Frame = +3

Query: 181 KTTGIVETH-FTFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSAYDLVLAEDE 239
           + TG+  +   +   + F  FD+GG R  R+ W   F  V  I+F V +           
Sbjct: 12  RPTGLPTSEELSMGGMTFTTFDLGGHRQARRVWKDYFPAVDGIVFIVDV----------H 161

Query: 240 EMNRMHESMKLFDSICNNKWFTDTSIILFLNKKD 273
           +  R+ E+    DS+  +    D  +++  NK D
Sbjct: 162 DTERITEAKAELDSLLRDDQIADIPVLVLGNKMD 263
>11378
          Length = 1688

 Score = 38.1 bits (87), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 27/102 (26%), Positives = 42/102 (41%)
 Frame = +3

Query: 172 QQDVLRTRVKTTGIVETHFTFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSAY 231
           + D +   V T        +   + F  FD+GG R  R+ W   F  V  I+F       
Sbjct: 384 KDDKMAQHVPTLHPTSEELSMGGMRFTTFDLGGHRQARRVWKDYFPAVDGIVF------- 542

Query: 232 DLVLAEDEEMNRMHESMKLFDSICNNKWFTDTSIILFLNKKD 273
            LV   D E  R+ E+    DS+  ++   +  I++  NK D
Sbjct: 543 -LVDVHDRE--RLVEAKAELDSLMTDEQVANAPILVLGNKID 659
>18208
          Length = 458

 Score = 31.2 bits (69), Expect = 0.61,   Method: Compositional matrix adjust.
 Identities = 11/34 (32%), Positives = 18/34 (52%)
 Frame = -1

Query: 193 KDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFCV 226
           K     ++D+GGQR  R  W + FE    +I+ +
Sbjct: 176 KGFKLNVWDIGGQRRIRPYWKNYFENTDLLIYVI 75
>08297
          Length = 541

 Score = 29.6 bits (65), Expect = 2.0,   Method: Compositional matrix adjust.
 Identities = 13/28 (46%), Positives = 17/28 (60%)
 Frame = +2

Query: 320 IYTHFTCATDTKNVQFVFDAVTDVIIKN 347
           I+ HFTCAT  K   FV   +T +I+ N
Sbjct: 5   IFHHFTCATPRKKSPFVVCFITQIILIN 88
>01191
          Length = 1681

 Score = 28.9 bits (63), Expect = 3.7,   Method: Compositional matrix adjust.
 Identities = 14/27 (51%), Positives = 17/27 (62%)
 Frame = -2

Query: 271 KKDLFEEKITQSSLTICFPEYTGANKY 297
           K  +F  KITQS  TI FP Y G +K+
Sbjct: 435 KLGIFVPKITQSVDTIAFPCYWGQSKF 355
>01021
          Length = 2238

 Score = 27.3 bits (59), Expect = 8.7,   Method: Compositional matrix adjust.
 Identities = 12/37 (32%), Positives = 24/37 (64%)
 Frame = +2

Query: 4   TVSAEDKAAAERSKMIDKNLREDGEKAAREVKLLLLG 40
           T+++ ++   + S+M+D  LRED  +A+R +K  + G
Sbjct: 812 TLNSLERDCDQISRMVDDKLREDSARASRNLKARVRG 922
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|21450241|ref|NP_659093.1| propionyl-Coenzyme A
carboxylase, alpha polypeptide [Mus musculus]
         (724 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

07274                                                                 252   1e-98
15060                                                                 250   2e-66
30553                                                                  47   3e-05
34243                                                                  44   3e-04
31960                                                                  43   4e-04
04102                                                                  30   4.4  
>07274
          Length = 1377

 Score =  252 bits (643), Expect(2) = 1e-98,   Method: Compositional matrix adjust.
 Identities = 117/234 (50%), Positives = 162/234 (69%)
 Frame = +1

Query: 367 QEMILVAKGYPLRHKQEDIPISGWAVECRVYAEDPYKSFGLPSIGRLSQYQEPIHLPGVR 426
             M+ VAKG+ L H+Q DIP+ GW+ ECRVYAEDP+K+FG+PSIGRLS+Y EP H+P VR
Sbjct: 1   HHMLRVAKGHELLHQQSDIPVDGWSFECRVYAEDPFKNFGMPSIGRLSRYIEPAHIPNVR 180

Query: 427 VDSGIQPGSDISIYYDPMISKLVTYGSDRAEALKRMEDALDNYVIRGVTHNIPLLREVII 486
            DSGIQ GS+ISIYYDPMI KLVT+G DR  A+  M  ALD+YVI+GVTHNIPLLR+++ 
Sbjct: 181 CDSGIQEGSEISIYYDPMICKLVTFGEDRQSAINTMITALDSYVIKGVTHNIPLLRDIMT 360

Query: 487 NTRFVKGDISTKFLSDVYPDGFKGHTLTLSERNQLLAIASSVFVASQLRAQRFQERSRVP 546
             RFV+GDI+T +L +V+PDGFKG  L+  E  QL+A+A +V      R++ F  ++R+P
Sbjct: 361 EGRFVQGDINTNYLPEVFPDGFKGKQLSEGEVEQLVALACAVHETHNQRSEDFINQTRMP 540

Query: 547 VIRPDVAKWELSVKLHDEDHTVVASNNGPAFTVEVDGSKLNVTSTWNLASPLLS 600
           V +   + W+++V++    +    + +  A+ V V  +   VT     ASP  +
Sbjct: 541 VTKDTRSSWDMAVEMAGTLYPATLTKHNTAYEVTVGDNLYTVTGELAFASPCWT 702

 Score =  127 bits (318), Expect(2) = 1e-98,   Method: Compositional matrix adjust.
 Identities = 62/132 (46%), Positives = 91/132 (68%)
 Frame = +3

Query: 593 NLASPLLSVNVDGTQRTVQCLSREAGGNMSIQFLGTVYKVHILTKLAAELNKFMLEKVPK 652
           +L  PLL + V+G ++ +Q + R  G N  ++  GTV+ V +L  +AA + +FM EK   
Sbjct: 678 SLRFPLLDLMVNGHRQLLQLVERGYGCNYKLRLFGTVFSVRVLDSVAASMQQFMPEKKEV 857

Query: 653 DTSSTLCSPMPGVVVAVSVKPGDMVAEGQEICVIEAMKMQNSMTAGKMGKVKLVHCKAGD 712
           D SS + +PMPG++ +V V+ GD VAEGQE+C++EAMKMQNS+ A K+  VK V+ K G+
Sbjct: 858 DMSSVVLAPMPGMLKSVDVQVGDQVAEGQEVCILEAMKMQNSLVAAKVSTVKKVNFKTGE 1037

Query: 713 TVGEGDLLVELE 724
           TV EGD++VE E
Sbjct: 1038TVNEGDVIVEFE 1073
>15060
          Length = 935

 Score =  250 bits (638), Expect = 2e-66,   Method: Compositional matrix adjust.
 Identities = 139/294 (47%), Positives = 192/294 (65%), Gaps = 3/294 (1%)
 Frame = -2

Query: 139 YGFLSENKEFAKRLAAEDVTFIGPDTHAIQAMGDKIESKLLAKRAKVNTIPGFDGVVKDA 198
           YGFLSE  +FA+      + F+GP    +  MGDK+E++  A  A V  +PG  G V  A
Sbjct: 934 YGFLSERPDFAQACVDAGIHFVGPSPEVVHRMGDKVEARQSAINAGVQVVPGTPGPVASA 755

Query: 199 DEAVRIAREIGYPVMIKASAGGGGKGMRIAWDDEETRDGFRFSSQEAASSFGDDRLLIEK 258
           +EA+   +E G PV+ KA+ GGGG+GMR+  + EE  + F  +  EA ++FGD  L IEK
Sbjct: 754 EEAMEFCKEHGLPVIFKAAFGGGGRGMRVVRNLEEVEENFNRAFSEALAAFGDGSLFIEK 575

Query: 259 FIDNPRHIEIQVLGDKHGNALWLNERECSIQRRNQKVVEEAPSIFLDPETRQAMGEQAVA 318
           FI+ PRHIE+Q+LGD+ GN + L ER+CS+QRR+QKVVE AP+  LD E R  M   AV 
Sbjct: 574 FIERPRHIEVQLLGDRTGNVIHLYERDCSVQRRHQKVVEIAPAPQLDSEVRTKMANDAVR 395

Query: 319 LAKAVKYSSAGTVEFLVDSQKNFYFLEMNTRLQVEHPVTECITGLDLVQEMILVAKGYPL 378
           LAK V Y +AGTVEFL+D    +YF+E+N RLQVEH VTE +TG+DLVQ  I +A+G  L
Sbjct: 394 LAKFVGYENAGTVEFLLDKNGQYYFIEVNARLQVEHTVTEQVTGVDLVQAQIRIAEGKTL 215

Query: 379 RH---KQEDIPISGWAVECRVYAEDPYKSFGLPSIGRLSQYQEPIHLPGVRVDS 429
                 Q+ I ++G A++CR+  EDP ++F  P  GR+  ++    + G+R+DS
Sbjct: 214 SDLDLTQDKIQLNGCAIQCRMTTEDPARNF-QPDTGRIEVFRSGEGM-GIRLDS 59
>30553
          Length = 615

 Score = 47.0 bits (110), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 24/58 (41%), Positives = 36/58 (62%)
 Frame = +2

Query: 649 KVPKDTSSTLCSPMPGVVVAVSVKPGDMVAEGQEICVIEAMKMQNSMTAGKMGKVKLV 706
           K  K    ++ +PMPG V+ + VK GD V +GQ + V+ AMKM+  +TA   G V+L+
Sbjct: 380 KALKGVRGSVGAPMPGEVIDIKVKEGDQVEKGQAVLVLSAMKMEMVVTAPMSGTVRLL 553
>34243
          Length = 503

 Score = 43.5 bits (101), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 26/63 (41%), Positives = 37/63 (58%)
 Frame = -1

Query: 659 CSPMPGVVVAVSVKPGDMVAEGQEICVIEAMKMQNSMTAGKMGKVKLVHCKAGDTVGEGD 718
            +PMPGV+  V V  G  V +G+ + V+ AMKM+  + A + G V+ V   AG TV +G 
Sbjct: 425 VAPMPGVIERVLVSEGATVEQGEPLVVMIAMKMEYIIRAPRAGVVEKVMFAAGQTVAKGT 246

Query: 719 LLV 721
            LV
Sbjct: 245 ALV 237
>31960
          Length = 667

 Score = 43.1 bits (100), Expect = 4e-04,   Method: Composition-based stats.
 Identities = 29/93 (31%), Positives = 41/93 (44%)
 Frame = -2

Query: 447 KLVTYGSDRAEALKRMEDALDNYVIRGVTHNIPLLREVIINTRFVKGDISTKFLSDVYPD 506
           + + +  D   A  +M  AL  + IRGV  NIP L  V+ N +F+ G + T F+ D  P 
Sbjct: 657 RFIAHARDHPTASSKMLRALKEFRIRGVKTNIPFLLNVLQNDKFLTGVVDTYFI-DENPQ 481

Query: 507 GFKGHTLTLSERNQLLAIASSVFVASQLRAQRF 539
            F+                   F ASQ RAQ+ 
Sbjct: 480 LFQ-------------------FQASQNRAQKL 439
>04102
          Length = 1749

 Score = 29.6 bits (65), Expect = 4.4,   Method: Compositional matrix adjust.
 Identities = 13/36 (36%), Positives = 21/36 (58%)
 Frame = +1

Query: 251 DDRLLIEKFIDNPRHIEIQVLGDKHGNALWLNEREC 286
           D  L +E   D   H+ I+ + DKHG A+ ++ R+C
Sbjct: 250 DFLLFVETKTDKQDHVFIKDIFDKHGYAINISSRKC 357
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|60218877|ref|NP_033017.2| ATP-binding cassette,
sub-family D, member 3 [Mus musculus]
         (659 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

12308                                                                 355   3e-98
19618                                                                 202   5e-52
19777                                                                 161   1e-39
05764                                                                  64   2e-10
01623                                                                  57   3e-08
02301                                                                  50   3e-06
30281                                                                  44   1e-04
22801                                                                  36   0.043
03538                                                                  36   0.043
01839                                                                  33   0.52 
38795                                                                  32   0.70 
33929                                                                  30   3.6  
>12308
          Length = 698

 Score =  355 bits (912), Expect = 3e-98,   Method: Compositional matrix adjust.
 Identities = 163/232 (70%), Positives = 200/232 (86%), Gaps = 1/232 (0%)
 Frame = -3

Query: 388 TARITELMQVLKDLNHGRYERTMVSQQEKGIEGAQAS-PLVPGAGEIINTDNIIKFDHVP 446
           TAR+T+L++VL+DLN+GRYERTMV+      +GA++S  L PG G++I  D++IKFD VP
Sbjct: 696 TARVTDLIKVLEDLNNGRYERTMVTSNGPRGDGAESSMKLKPGNGQLIFKDHVIKFDKVP 517

Query: 447 LATPNGDILIQDLSFEVRSGANVLICGPNGCGKSSLFRVLGELWPLFGGRLTKPERGKLF 506
           L TPNGD+LI +LSFEV++G NVL+CGPNGCGKSSLFR+LGELWPLFGG LTKPE+GKLF
Sbjct: 516 LVTPNGDVLIPELSFEVKAGMNVLVCGPNGCGKSSLFRILGELWPLFGGSLTKPEKGKLF 337

Query: 507 YVPQRPYMTLGTLRDQVIYPDGKEDQKKRGISDQVLKEYLDNVQLGHILEREGGWDSVQD 566
           Y+PQRPYMT+GTLRDQV YPD  E+Q ++G  D+ L + L  VQL ++L+REGGWD+VQD
Sbjct: 336 YIPQRPYMTVGTLRDQVTYPDSHEEQLRKGTRDEELADILGKVQLDYVLQREGGWDAVQD 157

Query: 567 WMDVLSGGEKQRMAMARLFYHKPQFAILDECTSAVSVDVEDYIYSHCRKVGI 618
           WMDVLSGGEKQR+AMARLFYHKPQFAILDECTSAVSVDVE ++Y + R+VGI
Sbjct: 156 WMDVLSGGEKQRIAMARLFYHKPQFAILDECTSAVSVDVEGFMYQYSREVGI 1
>19618
          Length = 974

 Score =  202 bits (513), Expect = 5e-52,   Method: Compositional matrix adjust.
 Identities = 93/138 (67%), Positives = 115/138 (83%)
 Frame = +2

Query: 522 QVIYPDGKEDQKKRGISDQVLKEYLDNVQLGHILEREGGWDSVQDWMDVLSGGEKQRMAM 581
           Q+IYP  ++D ++ G SD+ L  +LD VQL ++ +RE G D+++DW+DVLSGGEKQR+AM
Sbjct: 50  QIIYPHTRDDMRRLGKSDEDLLHFLDIVQLTYLEQREHGLDAIEDWIDVLSGGEKQRIAM 229

Query: 582 ARLFYHKPQFAILDECTSAVSVDVEDYIYSHCRKVGITLFTVSHRKSLWKHHEYYLHMDG 641
           ARLFYHKPQFAILDECTSAVSVDVE  +YS+CR+VGITLFTVSHRKSLW HH+YYL  DG
Sbjct: 230 ARLFYHKPQFAILDECTSAVSVDVEGKMYSYCREVGITLFTVSHRKSLWVHHDYYLQFDG 409

Query: 642 RGNYEFKKITEDTVEFGS 659
           RG+YEF+ I +D   FGS
Sbjct: 410 RGSYEFEAIDQDKEHFGS 463
>19777
          Length = 671

 Score =  161 bits (407), Expect = 1e-39,   Method: Compositional matrix adjust.
 Identities = 85/223 (38%), Positives = 130/223 (58%), Gaps = 6/223 (2%)
 Frame = -1

Query: 432 EIINTDNIIKFDHVPLATP-NGDILIQDLSFEVRSGANVLICGPNGCGKSSLFRVLGELW 490
           E+ +T+     + V    P +  +L +DLS ++ SG ++L+ G +GCGK+SL RV+  LW
Sbjct: 662 EMRSTEPAFSIESVTYGPPKSSHVLCRDLSLKLHSGTSILVTGDSGCGKTSLLRVIAGLW 483

Query: 491 PLFGG---RLTKPERGKLFYVPQRPYMTLGTLRDQVIYPDGKEDQKKRGISDQVLKEYLD 547
               G   R+ +    +L Y+PQ+PY+T G+LRDQ+++P  + D       D  +  YL 
Sbjct: 482 KSSTGYVDRIVEQIPSELLYLPQKPYLTTGSLRDQILFPSTEADVVP---DDDKMYRYLS 312

Query: 548 NVQLGHILEREGGWDSVQDW--MDVLSGGEKQRMAMARLFYHKPQFAILDECTSAVSVDV 605
              L  +LER GG D   DW   D  S GE QR++  R F+HKP+FA+LDE TS VS ++
Sbjct: 311 LAGLNQLLERLGGLDVNMDWNWYDEXSPGEMQRLSFVRXFFHKPRFALLDEATSQVSQEM 132

Query: 606 EDYIYSHCRKVGITLFTVSHRKSLWKHHEYYLHMDGRGNYEFK 648
           E  +Y  C+K+ ITL ++ HR S+  +H   LH  G G++  +
Sbjct: 131 EGTLYLQCQKLHITLLSIGHRDSIRPYHPLSLHFHGSGSWSTR 3
>05764
          Length = 1395

 Score = 63.9 bits (154), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 56/215 (26%), Positives = 96/215 (44%), Gaps = 23/215 (10%)
 Frame = -2

Query: 455  LIQDLSFEVRSGANVLICGPNGCGKSSLFRVLGELWPLFGGRL-----------TKPERG 503
            +++ +S E+ +G    + G +GCGKS++  +L   +    GRL               R 
Sbjct: 1082 VLKGISLEISAGQTAALVGISGCGKSTIISLLQRYYDPSKGRLLVDGTDVRDYNITALRS 903

Query: 504  KLFYVPQRPYMTLGTLRDQVIYPDGKEDQKKRGISDQVLKEYLDNVQLGHILE----REG 559
             L  V Q P +   ++RD + Y  G E       SD  + + +   +  +I E       
Sbjct: 902  LLSVVSQEPILFDCSIRDNIQY--GLE-------SDVPMPDIIAACKTANIHEFIASLPQ 750

Query: 560  GWDS-VQDWMDVLSGGEKQRMAMARLFYHKPQFAILDECTSAVSVDVEDYIYSHCRKV-- 616
            G+D+ V      LSGG+KQR+A+AR     P   +LDE TSA+  + E  + +       
Sbjct: 749  GYDTQVGGKGTQLSGGQKQRVAIARALVRNPIILLLDEATSALDTESEKLVQAALDNARE 570

Query: 617  GITLFTVSHRKSLWKHHEYYLHMDG-----RGNYE 646
            G T   ++HR S  ++ +    M+      +GN++
Sbjct: 569  GRTCIVIAHRLSTIQNADVIFVMENGQILEKGNHQ 465
>01623
          Length = 1414

 Score = 56.6 bits (135), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 57/209 (27%), Positives = 94/209 (44%), Gaps = 17/209 (8%)
 Frame = +3

Query: 440 IKFDHVPLATPN-GDILI-QDLSFEVRSGANVLICGPNGCGKSSLFRVLGELWPLFGGRL 497
           I+F  +  A P   D+ I +  + + R+G    + GP+G GKS++  +L   +    G++
Sbjct: 27  IEFRDIHFAYPGRPDVAIFKGFNLQARAGQVTAVVGPSGSGKSTVCGLLLRYYDPNAGQV 206

Query: 498 T---------KPE--RGKLFYVPQRPYMTLGTLRDQVIYPDGKEDQKKRG-ISDQVLKEY 545
                      P   R  +  V Q P +   ++ + + Y     D    G I D   K  
Sbjct: 207 MLDGQNIAELDPTWLRSHIGTVSQEPILFSCSVAENIAYGAVNPDAVTLGQIEDAARKAN 386

Query: 546 LDNVQLGHILEREGGWDS-VQDWMDVLSGGEKQRMAMARLFYHKPQFAILDECTSAVSVD 604
             N      L    G D+ V +   +LSGG++QR+A+AR     P+  +LDE TSA+  +
Sbjct: 387 AFNFVSTFPL----GLDTMVGERGMMLSGGQRQRIAIARAILKNPEILLLDEATSALDAE 554

Query: 605 VEDYIYSHCRKV--GITLFTVSHRKSLWK 631
            E  +     K+  G T+ T++HR S  K
Sbjct: 555 SEYLVQDALEKLMGGRTVITIAHRLSTIK 641
>02301
          Length = 1098

 Score = 49.7 bits (117), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 39/127 (30%), Positives = 61/127 (48%), Gaps = 4/127 (3%)
 Frame = -2

Query: 504 KLFYVPQRPYMTLGTLRDQVIYPDGKEDQKKRGISDQVLKEYLDNVQLGHILEREGGWD- 562
           K+  V Q P +   +++D + Y  G E      I    +K    +     I     G+D 
Sbjct: 872 KMALVGQEPVLFSRSIKDNIGY--GPEQYNDSDIVTAAMKANAHDF----IRALPRGYDT 711

Query: 563 SVQDWMDVLSGGEKQRMAMARLFYHKPQFAILDECTSAVSVDVEDYIYS---HCRKVGIT 619
           SV +   +LSGG+KQR+A+AR    +P   +LDE TSA+    E  + S    C + G T
Sbjct: 710 SVGERGLLLSGGQKQRLAIARALVRQPAILLLDEATSALDTQSESLVQSAINECTR-GRT 534

Query: 620 LFTVSHR 626
           +  ++HR
Sbjct: 533 VVIIAHR 513
>30281
          Length = 821

 Score = 44.3 bits (103), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 46/160 (28%), Positives = 72/160 (45%), Gaps = 16/160 (10%)
 Frame = -2

Query: 503 GKLFYVPQRPYMTLGTLRDQVIYPDGKEDQKKRGISDQVLKE----YLDNVQLGHILERE 558
           G++ YVPQ+ ++   T+RD +++       K + I +Q   E     L    L  I E+ 
Sbjct: 820 GRIAYVPQQAWIQNATVRDNILFGSPYIRSKYKAILEQCELERDVAMLPGGDLTQIGEK- 644

Query: 559 GGWDSVQDWMDVLSGGEKQRMAMARLFYHKPQFAILDECTSAVSVDVEDYIYSHCRKVGI 618
            G +        LSGG+KQR+++AR  Y      +LD+  SAV   V   I+S  + +G 
Sbjct: 643 -GIN--------LSGGQKQRVSVARAVYSDSDVYLLDDPLSAVDSHVGKAIFS--KVIGP 497

Query: 619 TLFTVSHRKSLWKHHEYYLH--------MDG----RGNYE 646
                   + L  H  ++L         MDG    RG+YE
Sbjct: 496 NGLLRGTTRVLVTHGVHWLPMVDEILVLMDGKISERGSYE 377
>22801
          Length = 753

 Score = 36.2 bits (82), Expect = 0.043,   Method: Compositional matrix adjust.
 Identities = 19/67 (28%), Positives = 33/67 (49%)
 Frame = -1

Query: 571 LSGGEKQRMAMARLFYHKPQFAILDECTSAVSVDVEDYIYSHCRKVGITLFTVSHRKSLW 630
           LSGG++ R+A+A L    P   +LDE T+ + ++  D +    +     +  VSH + L 
Sbjct: 732 LSGGQRARVALAELSCRAPDVLVLDEPTNNLDIESIDALADAIKNFTGGVIIVSHDERLI 553

Query: 631 KHHEYYL 637
           +     L
Sbjct: 552 RDTNCQL 532
>03538
          Length = 1974

 Score = 36.2 bits (82), Expect = 0.043,   Method: Compositional matrix adjust.
 Identities = 18/61 (29%), Positives = 32/61 (52%)
 Frame = -1

Query: 571  LSGGEKQRMAMARLFYHKPQFAILDECTSAVSVDVEDYIYSHCRKVGITLFTVSHRKSLW 630
            LSGG++ R+A+A L    P   +LDE T+ + ++  D +    +     +  VSH + L 
Sbjct: 1725 LSGGQRARVALAELSCRAPDVLVLDEPTNNLDIESIDALADAIKNFTGGVIIVSHDERLI 1546

Query: 631  K 631
            +
Sbjct: 1545 R 1543
>01839
          Length = 2346

 Score = 32.7 bits (73), Expect = 0.52,   Method: Compositional matrix adjust.
 Identities = 22/71 (30%), Positives = 33/71 (46%), Gaps = 4/71 (5%)
 Frame = +2

Query: 103  MIQNGTLIESGIIGRSSKDFKRYLFNFIAAMPLISLVNNFLKYGLNELKLC----FRVRL 158
            +I    L+ S I   SS     +LF     +  ++L+NN+L +      LC    F V L
Sbjct: 1118 LISFSVLVFSFIHTASSPA-NLFLFVLFVCLFFLTLLNNYLDFNCMLFHLCTANIFLVNL 1294

Query: 159  TRYLYEEYLQA 169
            T Y +  +LQA
Sbjct: 1295 TDYFFRIFLQA 1327
>38795
          Length = 792

 Score = 32.3 bits (72), Expect = 0.70,   Method: Compositional matrix adjust.
 Identities = 15/36 (41%), Positives = 23/36 (63%), Gaps = 1/36 (2%)
 Frame = +1

Query: 455 LIQDLSFEVRSGANVLICGPNGCGKSSLFRVL-GEL 489
           + Q+L F +     V + GPNG GKS+L +++ GEL
Sbjct: 682 IYQNLDFGIDLDTRVALVGPNGAGKSTLLKLISGEL 789
>33929
          Length = 408

 Score = 29.6 bits (65), Expect = 3.6,   Method: Composition-based stats.
 Identities = 15/37 (40%), Positives = 19/37 (51%)
 Frame = +1

Query: 451 NGDILIQDLSFEVRSGANVLICGPNGCGKSSLFRVLG 487
           +G  L+ D   E+  G    + G NGCGKSSL   L 
Sbjct: 232 HGAELLMDSKLEMNVGKRYGLIGLNGCGKSSLLAALA 342
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|34328138|ref|NP_032469.2| kinesin family member 3A
[Mus musculus]
         (701 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

33215                                                                 354   5e-98
12048                                                                 179   4e-55
34477                                                                 186   2e-47
38050                                                                  80   2e-42
02896                                                                 135   4e-32
28434                                                                 133   3e-31
13148                                                                 124   2e-28
11818                                                                 119   4e-27
15043                                                                 108   6e-24
14618                                                                  95   7e-20
34899                                                                  83   8e-17
17748                                                                  65   4e-16
36593                                                                  52   6e-07
38061                                                                  36   0.042
36649                                                                  29   6.0  
>33215
          Length = 696

 Score =  354 bits (909), Expect = 5e-98,   Method: Compositional matrix adjust.
 Identities = 164/216 (75%), Positives = 193/216 (89%)
 Frame = +1

Query: 149 YLEIYNEEVRDLLGKDQTQRLEVKERPDVGVYIKDLSAYVVNNADDMDRIMTLGHKNRSV 208
           YLEIY EE+RDLL KDQ++RLE+K RPD GVY+KDLS++V  +  +++ +M +G++NRSV
Sbjct: 1   YLEIYQEEIRDLLSKDQSKRLELKXRPDTGVYVKDLSSFVTKSVREIEHVMNVGNQNRSV 180

Query: 209 GATNMNEHSSRSHAIFTITIECSEKGVDGNMHVRMGKLHLVDLAGSERQAKTGATGQRLK 268
           GATNMNEHSSRSHAIF IT+ECSE G DG  H+R+GKL++VDLAGSERQAKTGATG RLK
Sbjct: 181 GATNMNEHSSRSHAIFIITVECSEIGADGENHIRVGKLNMVDLAGSERQAKTGATGDRLK 360

Query: 269 EATKINLSLSTLGNVISALVDGKSTHVPYRNSKLTRLLQDSLGGNSKTMMCANIGPADYN 328
           EATKINLSLS L NVISALVD K+TH+PYR+SKLTRLLQDSLGGNSKT M ANIGPA YN
Sbjct: 361 EATKINLSLSALSNVISALVDAKTTHIPYRDSKLTRLLQDSLGGNSKTTMVANIGPASYN 540

Query: 329 YDETISTLRYANRAKNIKNKARINEDPKDALLRQFQ 364
           +DET++TLRYANRAK+IKNK +INEDPKDALLR+FQ
Sbjct: 541 FDETLTTLRYANRAKSIKNKPKINEDPKDALLREFQ 648
>12048
          Length = 1162

 Score =  179 bits (453), Expect(2) = 4e-55,   Method: Compositional matrix adjust.
 Identities = 112/252 (44%), Positives = 144/252 (57%), Gaps = 7/252 (2%)
 Frame = +2

Query: 103 GTGKTFTMEGVRAVPGLRGVIPNSFAHIFGHIAKAEGDTRFLVRVSYLEIYNEEVRDLLG 162
           G GKTFT+ G       RG+IP S ++I+    K   +  F V +SYLEIYN+   DLL 
Sbjct: 410 GGGKTFTITGGAERYMDRGLIPRSLSYIYEQTEK-NPELSFTVHISYLEIYNDSGYDLLD 586

Query: 163 -KDQTQRLE------VKERPDVGVYIKDLSAYVVNNADDMDRIMTLGHKNRSVGATNMNE 215
            K +  +LE      + E  D  +++++LS +  N+ ++   ++ LG  NR +  T MN+
Sbjct: 587 PKHEAAKLEDLPKVNLLEDSDQNIHLRNLSVHQANSEEEALNLLFLGDTNRMIAETPMNQ 766

Query: 216 HSSRSHAIFTITIECSEKGVDGNMHVRMGKLHLVDLAGSERQAKTGATGQRLKEATKINL 275
            SSRSH IFTI I   E G   +  +R  K HLVDLAGSER AKT   GQ L EA  IN 
Sbjct: 767 ASSRSHCIFTIHITTRETG---SATIRRAKYHLVDLAGSERVAKTNVNGQLLTEARYINS 937

Query: 276 SLSTLGNVISALVDGKSTHVPYRNSKLTRLLQDSLGGNSKTMMCANIGPADYNYDETIST 335
           SL  L  VI AL +    HVPYRNS +T +L+DSLGGN  T M A       N DE+IST
Sbjct: 938 SLHFLELVIIALSEKSRQHVPYRNSMMTSVLRDSLGGNCMTTMIATCSMEKRNMDESIST 1117

Query: 336 LRYANRAKNIKN 347
            R+A R   IKN
Sbjct: 1118CRFAQRVAMIKN 1153

 Score = 55.1 bits (131), Expect(2) = 4e-55,   Method: Compositional matrix adjust.
 Identities = 22/38 (57%), Positives = 32/38 (84%)
 Frame = +1

Query: 66  VFGPESKQLDVYNLTARPIIDSVLEGYNGTIFAYGQTG 103
           +F P++ Q +V+   A+P+ID+VL+GYNGT+FAYGQTG
Sbjct: 298 MF*PKTNQDEVFQNVAKPVIDNVLQGYNGTVFAYGQTG 411
>34477
          Length = 811

 Score =  186 bits (473), Expect = 2e-47,   Method: Compositional matrix adjust.
 Identities = 97/133 (72%), Positives = 107/133 (80%), Gaps = 1/133 (0%)
 Frame = +3

Query: 233 KGVDGNMHVRMGKLHLVDLAGSERQAKTGATGQRLKEATKINLSLSTLGNVISALVDGKS 292
           +G DG  HVR+GKLHLVDLAGSERQAKTGATGQRLKEATKINLSLSTLGNVIS +  G+ 
Sbjct: 162 EGGDGEQHVRVGKLHLVDLAGSERQAKTGATGQRLKEATKINLSLSTLGNVIS-VPGGRQ 338

Query: 293 THV-PYRNSKLTRLLQDSLGGNSKTMMCANIGPADYNYDETISTLRYANRAKNIKNKARI 351
            H  P +  +         G   +T+M AN+GPADYNYDETISTLRYANRAKNIKNKA+I
Sbjct: 339 EHTHPLQELQAHSPAAGLPGRQLQTVMVANMGPADYNYDETISTLRYANRAKNIKNKAKI 518

Query: 352 NEDPKDALLRQFQ 364
           NEDPKDALLRQFQ
Sbjct: 519 NEDPKDALLRQFQ 557

 Score =  160 bits (405), Expect = 1e-39,   Method: Compositional matrix adjust.
 Identities = 79/137 (57%), Positives = 93/137 (67%)
 Frame = +1

Query: 179 VYIKDLSAYVVNNADDMDRIMTLGHKNRSVGATNMNEHSSRSHAIFTITIECSEKGVDGN 238
           VY+KDLSA+VVNNADDMDRIMTLG+KNRSVG+TNMN HSSRSHAIFT+T+ECSEKG  G+
Sbjct: 1   VYVKDLSAFVVNNADDMDRIMTLGNKNRSVGSTNMNMHSSRSHAIFTVTVECSEKGATGS 180

Query: 239 MHVRMGKLHLVDLAGSERQAKTGATGQRLKEATKINLSLSTLGNVISALVDGKSTHVPYR 298
                         G   + +        ++  +             +LVDGKSTH+PYR
Sbjct: 181 SMYVWANCTWWTWXGQRDKPRQEPQASA*RKRPRSTCLCQLWAM*YRSLVDGKSTHIPYR 360

Query: 299 NSKLTRLLQDSLGGNSK 315
           NSKLTRLLQDSLGGNSK
Sbjct: 361 NSKLTRLLQDSLGGNSK 411

 Score = 42.0 bits (97), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 19/30 (63%), Positives = 24/30 (80%)
 Frame = +3

Query: 421 MVEMQAKIDEERKALETKLDMEEEERNKAR 450
           M E+QAKID +R+ LE+K DM EEERNK +
Sbjct: 714 MAEIQAKIDSDRRVLESKKDMAEEERNKVK 803
>38050
          Length = 809

 Score = 79.7 bits (195), Expect(3) = 2e-42,   Method: Compositional matrix adjust.
 Identities = 35/54 (64%), Positives = 43/54 (79%)
 Frame = -3

Query: 311 GGNSKTMMCANIGPADYNYDETISTLRYANRAKNIKNKARINEDPKDALLRQFQ 364
           G NSKT+M A + PAD NY+ET+STLRYA+RAK IK KA +NEDP D L+R+ Q
Sbjct: 300 GWNSKTIMVAALSPADINYEETLSTLRYADRAKQIKTKAMVNEDPTDKLIRELQ 139

 Score = 70.9 bits (172), Expect(3) = 2e-42,   Method: Compositional matrix adjust.
 Identities = 40/96 (41%), Positives = 53/96 (55%)
 Frame = -2

Query: 169 LEVKERPDVGVYIKDLSAYVVNNADDMDRIMTLGHKNRSVGATNMNEHSSRSHAIFTITI 228
           L +++ P  G Y   L    V + +D+++ M  G  NR+V ATNMN  SSR+H I  IT 
Sbjct: 733 LRIRQHPKNGFYADGLQVVPVVSYEDIEKKMEAGTTNRTVAATNMNATSSRAHTIVGITF 554

Query: 229 ECSEKGVDGNMHVRMGKLHLVDLAGSERQAKTGATG 264
               K   G    +   ++LVDLAGSER   TGATG
Sbjct: 553 MQKFKNAAGEETTKSALINLVDLAGSERADSTGATG 446

 Score = 62.0 bits (149), Expect(3) = 2e-42,   Method: Compositional matrix adjust.
 Identities = 31/55 (56%), Positives = 40/55 (72%), Gaps = 3/55 (5%)
 Frame = -1

Query: 264 GQRLKEATKINLSLSTLGNVISALVD---GKSTHVPYRNSKLTRLLQDSLGGNSK 315
           G RLKE   IN SLS LGN ISAL D   GK+  VP+R+S LT+LL+++LGG ++
Sbjct: 449 GDRLKEGAAINQSLSCLGNCISALADKAGGKNVKVPFRDSALTKLLKNALGGTAR 285
>02896
          Length = 2076

 Score =  135 bits (341), Expect = 4e-32,   Method: Compositional matrix adjust.
 Identities = 74/182 (40%), Positives = 110/182 (60%)
 Frame = +1

Query: 179 VYIKDLSAYVVNNADDMDRIMTLGHKNRSVGATNMNEHSSRSHAIFTITIECSEKGVDGN 238
           ++ + L++++  N ++   ++  G  NRS+ A ++N  SSRSH IFT+ +E S   V  +
Sbjct: 10  LWSRGLASHLAQNEEEALNLLFEGETNRSIAAHSLNRMSSRSHCIFTVYLE-SRSRVQSS 186

Query: 239 MHVRMGKLHLVDLAGSERQAKTGATGQRLKEATKINLSLSTLGNVISALVDGKSTHVPYR 298
               + KL+ VDLAGSER  K+ + G+ + EA  IN SLS L  V+ AL D    H+P+R
Sbjct: 187 AKYTVSKLNFVDLAGSERIGKSKSEGKMVTEAMYINKSLSFLEQVVIALADKNRDHIPFR 366

Query: 299 NSKLTRLLQDSLGGNSKTMMCANIGPADYNYDETISTLRYANRAKNIKNKARINEDPKDA 358
            SKLT  L+DS+GGN  T++ AN+       +ET+STLR+A R   + N+  INE    A
Sbjct: 367 QSKLTHYLKDSIGGNCNTVLIANVWGERAQLEETVSTLRFATRMMCVANEPAINEVYDPA 546

Query: 359 LL 360
           LL
Sbjct: 547 LL 552
>28434
          Length = 777

 Score =  133 bits (334), Expect = 3e-31,   Method: Compositional matrix adjust.
 Identities = 72/118 (61%), Positives = 85/118 (72%), Gaps = 3/118 (2%)
 Frame = +2

Query: 250 DLAGSERQAKTGATGQRLKEATKINLSLSTLGNVISALVDG--KSTHVPYRNSKLTRLLQ 307
           DLAGSER  +T A G R KE   IN  L  LGNVISAL +   K  H+PYR+SKLTRLLQ
Sbjct: 62  DLAGSERAKRTRAEGDRFKEGVNINRGLLALGNVISALGEDVQKRGHIPYRDSKLTRLLQ 241

Query: 308 DSLGGNSKTMMCANIGPADYNYDETISTLRYANRAKNIKNKARINEDPK-DALLRQFQ 364
           DSLGGNS T+M A + PAD N +ET++TLRYA+RA+ IKNK  IN DP+ D +LR  Q
Sbjct: 242 DSLGGNSHTLMVACVSPADSNMEETLNTLRYADRARKIKNKPVINRDPQSDEILRLRQ 415
>13148
          Length = 653

 Score =  124 bits (310), Expect = 2e-28,   Method: Compositional matrix adjust.
 Identities = 73/180 (40%), Positives = 103/180 (57%)
 Frame = -3

Query: 97  FAYGQTGTGKTFTMEGVRAVPGLRGVIPNSFAHIFGHIAKAEGDTRFLVRVSYLEIYNEE 156
           F        KT TMEGV     L+G+IP     IF +I   + +  F ++VSY EIY ++
Sbjct: 528 FCLWSNVQWKTHTMEGVLGNESLQGIIPRIVQDIFNYIYGMDENLEFHIKVSYFEIYMDK 349

Query: 157 VRDLLGKDQTQRLEVKERPDVGVYIKDLSAYVVNNADDMDRIMTLGHKNRSVGATNMNEH 216
           +RDLL   +T  L V E  +   Y+K  +   V++ +++  ++  G  NR V  TNMNEH
Sbjct: 348 IRDLLDVTKTN-LSVHEDKNRVPYVKGCTERFVSSPEEVMEVVDEGKSNRHVAVTNMNEH 172

Query: 217 SSRSHAIFTITIECSEKGVDGNMHVRMGKLHLVDLAGSERQAKTGATGQRLKEATKINLS 276
           SSRSH++F I ++      +  +H   GKL+LVDLAGSE+ +KTGA G  L EA  IN S
Sbjct: 171 SSRSHSVFLIHVKQENVDSEKKLH---GKLYLVDLAGSEKVSKTGAEGAVLDEAKNINRS 1

 Score = 65.1 bits (157), Expect = 9e-11,   Method: Composition-based stats.
 Identities = 29/48 (60%), Positives = 33/48 (68%)
 Frame = -1

Query: 59  KTFTFDTVFGPESKQLDVYNLTARPIIDSVLEGYNGTIFAYGQTGTGK 106
           K F FD V  P   Q  VY +TA+PI+  VL GYNGTIFAYGQT +GK
Sbjct: 641 KVFMFDKVLKPNVTQEYVYTVTAKPIVADVLSGYNGTIFAYGQTSSGK 498
>11818
          Length = 657

 Score =  119 bits (298), Expect = 4e-27,   Method: Compositional matrix adjust.
 Identities = 80/184 (43%), Positives = 104/184 (56%), Gaps = 6/184 (3%)
 Frame = -1

Query: 104 TGKTFTMEGVRAVP-----GLRGVIPNSFAHIFGHIAKAEGDTRFLVRVSYLEIYNEEVR 158
           +GKT+TM G           L G+IP     +F  IA+   D  F V VSYLEIYNE++ 
Sbjct: 657 SGKTYTMGGCYDAALSHDDDLVGIIPRILGDLFNGIAE-RSDYTFKVTVSYLEIYNEDLL 481

Query: 159 DLLG-KDQTQRLEVKERPDVGVYIKDLSAYVVNNADDMDRIMTLGHKNRSVGATNMNEHS 217
           DLL    Q Q L ++E  +  + IK L    V + +D    ++ G ++R+ GAT MN+ S
Sbjct: 480 DLLCLPSQRQPLSIREEMNGEIKIKGLKEVEVGSLEDTLMCLSQGARSRTTGATAMNDTS 301

Query: 218 SRSHAIFTITIECSEKGVDGNMHVRMGKLHLVDLAGSERQAKTGATGQRLKEATKINLSL 277
           SRSHAIFT+ IE S+K  D N H  + K HLVDLAGSER  KT A G R KE   I ++ 
Sbjct: 300 SRSHAIFTVHIEKSKK-EDMNDHC-IAKFHLVDLAGSERAKKTRAEGDRFKEGVNITVAC 127

Query: 278 STLG 281
              G
Sbjct: 126 LPWG 115

 Score = 57.8 bits (138), Expect = 2e-08,   Method: Composition-based stats.
 Identities = 32/56 (57%), Positives = 40/56 (71%), Gaps = 2/56 (3%)
 Frame = -3

Query: 264 GQRLKEATKINLSLSTLGNVISALVDG--KSTHVPYRNSKLTRLLQDSLGGNSKTM 317
           G++++   K    L  LGNVISAL +   K  H+PYR+SKLTRLLQDSLGGNS T+
Sbjct: 169 GRQIQRRCKHYRGLLALGNVISALGEDVQKRGHIPYRDSKLTRLLQDSLGGNSHTL 2
>15043
          Length = 973

 Score =  108 bits (271), Expect = 6e-24,   Method: Compositional matrix adjust.
 Identities = 67/162 (41%), Positives = 90/162 (55%), Gaps = 9/162 (5%)
 Frame = +2

Query: 202 GHKNRSVGATNMNEHSSRSHAIFTITIECSEK-----GVDGNMHVRMGKLHLVDLAGSER 256
           G + R +GAT++  H +R+HA+FTIT+E  E+     GV  N       + LV+LAG E 
Sbjct: 26  GRRARRMGATDIKAHRARAHAVFTITVEQKERQSSKVGVRAN-------IMLVELAGCE- 181

Query: 257 QAKTGATGQRLKEATKINLSLSTLG--NVISALVDGKST--HVPYRNSKLTRLLQDSLGG 312
                       +AT   +   T G  NV+ AL D K    HVPYR S +TRLLQD+LGG
Sbjct: 182 ----------AADATDPKILAGTQGVVNVLKALGDSKQIGGHVPYRESLVTRLLQDTLGG 331

Query: 313 NSKTMMCANIGPADYNYDETISTLRYANRAKNIKNKARINED 354
           N+ T+M   + P D +Y  T S L+Y   AK +KN AR+N D
Sbjct: 332 NAMTLMLVTVSPLDKSYQTTQSALQYGQFAKTVKNHARMNLD 457
>14618
          Length = 724

 Score = 95.1 bits (235), Expect = 7e-20,   Method: Compositional matrix adjust.
 Identities = 58/163 (35%), Positives = 97/163 (59%), Gaps = 6/163 (3%)
 Frame = -2

Query: 61  FTFDTVFGPESKQLDVYNLTARPIIDSVLEGYNGTIFAYGQTGTGKTFTME-GVRAVPGL 119
           F+FD VF P++ Q DV+   ++ ++ S L+GYN  IFAYGQTG+GKT+TME G+      
Sbjct: 483 FSFDRVFHPDNTQQDVFEEISQ-LVQSALDGYNVCIFAYGQTGSGKTYTMEGGLVGDEDT 307

Query: 120 RGVIPNSFAHIFGHIAKAEGDT--RFLVRVSYLEIYNEEVRDLLGKDQTQRLEVKER--- 174
           +G+IP + + IF   A+   D   ++    S++EIYNE + DLL  ++ + ++ + R   
Sbjct: 306 KGMIPRAVSQIFS-TARELQDKGWQYKFTTSFVEIYNEMIGDLLSSNKXKNVKHEIRMAG 130

Query: 175 PDVGVYIKDLSAYVVNNADDMDRIMTLGHKNRSVGATNMNEHS 217
            D  V + +L+   V +  ++ +++    +NR+V AT  NE S
Sbjct: 129 RDNNVAVTNLTTVDVTSQHEIAKLLRQASENRAVAATKCNERS 1
>34899
          Length = 564

 Score = 83.2 bits (204), Expect(2) = 8e-17,   Method: Compositional matrix adjust.
 Identities = 47/161 (29%), Positives = 84/161 (52%)
 Frame = +3

Query: 62  TFDTVFGPESKQLDVYNLTARPIIDSVLEGYNGTIFAYGQTGTGKTFTMEGVRAVPGLRG 121
           + D  +GP++K   +Y      ++   LEGYN TI A+G TG+GK+F M G        G
Sbjct: 3   SLDGAYGPDAKNGQIYQEKCDSMVQRALEGYNVTIMAFGATGSGKSFLMNGNDQEI---G 173

Query: 122 VIPNSFAHIFGHIAKAEGDTRFLVRVSYLEIYNEEVRDLLGKDQTQRLEVKERPDVGVYI 181
           V P     +F H+ +   +   +V  S++EI +E++ DLL     + + V++    G+++
Sbjct: 174 VAPMVIQQLFQHL-RQRSNKESMVTASFVEILDEKMTDLL-NPHNRPMAVRQHVIKGIFV 347

Query: 182 KDLSAYVVNNADDMDRIMTLGHKNRSVGATNMNEHSSRSHA 222
             LS  V    +++ ++   G + R +GAT++  H +R  A
Sbjct: 348 DGLSEMVARTGEELSQLYEQGRRARRMGATDIKAHRARYDA 470

 Score = 22.3 bits (46), Expect(2) = 8e-17,   Method: Composition-based stats.
 Identities = 8/16 (50%), Positives = 14/16 (87%)
 Frame = +1

Query: 218 SRSHAIFTITIECSEK 233
           +++HA+FTIT+E  E+
Sbjct: 517 TKAHAVFTITVEQKER 564
>17748
          Length = 621

 Score = 64.7 bits (156), Expect(2) = 4e-16,   Method: Compositional matrix adjust.
 Identities = 49/128 (38%), Positives = 69/128 (53%), Gaps = 7/128 (5%)
 Frame = -3

Query: 87  SVLEGYNGTIFAYGQTGTGKTFTMEGVRAVPGLR------GVIPNSFAHIFGHIAKAEGD 140
           ++ +GYN T+ AYGQTG+GKTF+M G      L+      G+IP     +F  I +   D
Sbjct: 379 ALFKGYNATVLAYGQTGSGKTFSMGGCYEAS-LKLDEEAMGIIPRIIKDLFNGI-QERPD 206

Query: 141 TRFLVRVSYLEIYNEEVRDLLGK-DQTQRLEVKERPDVGVYIKDLSAYVVNNADDMDRIM 199
             F V VSYLEIYNEE+ BLL    Q Q L ++E  +  + IK L    V + DD    +
Sbjct: 205 HTFKVTVSYLEIYNEELLBLLCPLSQRQPLTIREELNGEIKIKGLKEVTVGSVDDTLDCL 26

Query: 200 TLGHKNRS 207
           + G + R+
Sbjct: 25  SQGAQLRT 2

 Score = 38.9 bits (89), Expect(2) = 4e-16,   Method: Composition-based stats.
 Identities = 23/75 (30%), Positives = 38/75 (50%)
 Frame = -2

Query: 15  VKVVVRCRPLNEREKSMCYRQAVSVDEMRGTITVHKTDSSNEPPKTFTFDTVFGPESKQL 74
           V+V +R RPL  +E+S   +  +  +  +  + + K        K FTFD VF P+  Q 
Sbjct: 575 VRVALRARPLIAKEESEGCQTCLWYNSSQPQVVLGKD-------KPFTFDYVFSPKHNQQ 417

Query: 75  DVYNLTARPIIDSVL 89
           DVY  +A+ ++ S  
Sbjct: 416 DVYEKSAQTLVTSTF 372
>36593
          Length = 466

 Score = 52.4 bits (124), Expect = 6e-07,   Method: Composition-based stats.
 Identities = 23/41 (56%), Positives = 33/41 (80%)
 Frame = +1

Query: 301 KLTRLLQDSLGGNSKTMMCANIGPADYNYDETISTLRYANR 341
           KLT LLQ+SLGGNSKT+M  N+ P + N+ ET+++LR+A +
Sbjct: 1   KLTYLLQNSLGGNSKTLMFVNVSPKEENFSETLNSLRFATK 123
>38061
          Length = 206

 Score = 36.2 bits (82), Expect = 0.042,   Method: Compositional matrix adjust.
 Identities = 15/28 (53%), Positives = 22/28 (78%)
 Frame = -3

Query: 318 MCANIGPADYNYDETISTLRYANRAKNI 345
           + A + PAD N +ET++TLRYA+RA+ I
Sbjct: 84  LVACVSPADSNMEETLNTLRYADRARKI 1
>36649
          Length = 712

 Score = 29.3 bits (64), Expect = 6.0,   Method: Compositional matrix adjust.
 Identities = 19/59 (32%), Positives = 27/59 (45%), Gaps = 1/59 (1%)
 Frame = -3

Query: 66  VFGPESKQLDVYNLTARPI-IDSVLEGYNGTIFAYGQTGTGKTFTMEGVRAVPGLRGVI 123
            F  E +Q   Y LT +P+ + S  + + GTIF     GTG  F + G    P   G +
Sbjct: 596 TFSVEPQQTKQYELTYKPVTMTSENKKHQGTIFFPLPDGTGLLFNLVGTAEPPKPNGKV 420
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|21704096|ref|NP_663531.1| TAR DNA binding protein
isoform 1 [Mus musculus]
         (414 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

12350                                                                 353   7e-98
21869                                                                  95   5e-20
03406                                                                  93   2e-19
19868                                                                  86   3e-17
03000                                                                  84   9e-17
31618                                                                  67   2e-14
11019                                                                  68   6e-12
26197                                                                  62   5e-10
32386                                                                  58   9e-09
16016                                                                  56   3e-08
23322                                                                  54   8e-08
02415                                                                  51   1e-06
24983                                                                  50   2e-06
33516                                                                  49   5e-06
25691                                                                  47   1e-05
00302                                                                  44   1e-04
30672                                                                  43   3e-04
35180                                                                  43   3e-04
01937                                                                  42   4e-04
23250                                                                  41   7e-04
20488                                                                  41   0.001
05273                                                                  40   0.001
14637                                                                  40   0.002
20169                                                                  40   0.002
23720                                                                  39   0.003
04988                                                                  39   0.003
03744                                                                  39   0.004
00817                                                                  39   0.005
17681                                                                  39   0.005
11126                                                                  38   0.007
02343                                                                  38   0.007
15371                                                                  38   0.010
17775                                                                  37   0.015
11108                                                                  36   0.025
02809                                                                  36   0.025
13822                                                                  35   0.062
00029                                                                  35   0.064
02064                                                                  34   0.086
00556                                                                  34   0.092
28605                                                                  34   0.11 
09968                                                                  33   0.16 
02347                                                                  33   0.16 
16427                                                                  33   0.29 
08958                                                                  32   0.52 
23655                                                                  32   0.56 
14258                                                                  32   0.62 
09736                                                                  30   1.7  
19556                                                                  30   1.9  
12506                                                                  29   3.1  
25950                                                                  29   3.9  
33504                                                                  29   4.2  
19246                                                                  28   7.6  
>12350
          Length = 975

 Score =  353 bits (906), Expect = 7e-98,   Method: Compositional matrix adjust.
 Identities = 169/266 (63%), Positives = 211/266 (79%), Gaps = 1/266 (0%)
 Frame = -2

Query: 1   MSEYIRVTEDENDEPIEIPSEDDGTVLLSTVTAQFPGACGLRYRNPVSQCMRGVRLVEGI 60
           M++YIR   D+ DE +E+P E+DGT+LLST++AQFPG+CGL+YRNP S  MRG+RL +G 
Sbjct: 917 MNKYIRAVADDGDEALELPIEEDGTILLSTLSAQFPGSCGLKYRNPDSGTMRGIRLSDGR 738

Query: 61  LHAPDAGWGNLVYVVNYPKDNKRKMDETDASSAVKVKRAV-QKTSDLIVLGLPWKTTEQD 119
           L+ PD  WG  V+V  +PK+ K     +D      VK +  QK SDLIVLGLPWK+TE D
Sbjct: 737 LYPPDNHWGKQVFVCVFPKEGK-----SDHPGPKVVKSSSRQKCSDLIVLGLPWKSTEDD 573

Query: 120 LKDYFSTFGEVLMVQVKKDLKTGHSKGFGFVRFTEYETQVKVMSQRHMIDGRWCDCKLPN 179
           L+ YFS FG++LMVQVKKD KTG SKGFGF+RF EYE+Q+K M+QRHMIDGRWCD ++PN
Sbjct: 572 LRSYFSQFGDLLMVQVKKDPKTGQSKGFGFIRFAEYESQLKCMAQRHMIDGRWCDVRIPN 393

Query: 180 SKQSPDEPLRSRKVFVGRCTEDMTAEELQQFFCQYGEVVDVFIPKPFRAFAFVTFADDKV 239
           SK+   + L +RK+FVGRCT+DMTA++L+QFF ++GEVVDVFIP+PFRAFAFV+FAD +V
Sbjct: 392 SKEGAQQ-LMNRKIFVGRCTDDMTADDLRQFFSKFGEVVDVFIPRPFRAFAFVSFADPEV 216

Query: 240 AQSLCGEDLIIKGISVHISNAEPKHN 265
           AQSL GED IIKG SVHIS A PK N
Sbjct: 215 AQSLYGEDHIIKGASVHISGAAPKPN 138
>21869
          Length = 503

 Score = 94.7 bits (234), Expect = 5e-20,   Method: Compositional matrix adjust.
 Identities = 47/134 (35%), Positives = 79/134 (58%), Gaps = 3/134 (2%)
 Frame = -2

Query: 1   MSEYIRVTEDENDEPIEIPSEDDGTVLLSTVTAQFPGACGLRYRNPVSQCMRGVRLVEGI 60
           M+++I+V E+  D+P+EIPSE DGT+LL+T+ AQ+PGACGL+Y++      RG+RL EG+
Sbjct: 400 MAQFIQVCEEIGDDPVEIPSEGDGTLLLTTLNAQYPGACGLKYKSETG-AYRGIRLAEGV 224

Query: 61  LHAPDAGWGNLVYVVNYPKDNKRKMDETDASSAVKVKRAVQKTSDL---IVLGLPWKTTE 117
           L+ PD  WG+  ++  +PK  +    E  A  A   +R     ++    +  G P +   
Sbjct: 223 LYPPDGHWGSHQFIAVFPKQIQPSAKERMALVARPPRRGWWTPTNARISLSWGCPGRAQR 44

Query: 118 QDLKDYFSTFGEVL 131
              +    +FG+++
Sbjct: 43  TTSRPTSVSFGDLV 2
>03406
          Length = 1292

 Score = 93.2 bits (230), Expect = 2e-19,   Method: Compositional matrix adjust.
 Identities = 59/164 (35%), Positives = 87/164 (53%), Gaps = 7/164 (4%)
 Frame = +3

Query: 106 LIVLGLPWKTTEQDLKDYFSTFGEVLMVQVKKDLKTGHSKGFGFVRFTEYET-QVKVMSQ 164
           + V GL W+T  + L++YF  FGEV    +K DL +G S+GFGFV F E  T    V ++
Sbjct: 246 IFVGGLSWETXSKHLREYFEKFGEVTSCTLKTDLDSGKSRGFGFVVFKEAATVDAVVKNK 425

Query: 165 RHMIDGRWCDCKLPNSKQSPDEPLRSRKVFVGRCTEDMTAEELQQFFCQYGEVVDVFIP- 223
            H + GR  D K  N ++        RK+FVG+    +  E+++ +F ++G+VV+V +P 
Sbjct: 426 EHKLQGRKIDPKPANPRKG------MRKIFVGKLDPGVPQEDVESYFAKFGKVVNVELPY 587

Query: 224 ----KPFRAFAFVTFADDK-VAQSLCGEDLIIKGISVHISNAEP 262
                  RAF FV F +DK V + L      I G  V +  A P
Sbjct: 588 DKVKDQRRAFCFVEFDNDKTVKKVLEQTSHKIGGQEVDVKKATP 719

 Score = 30.4 bits (67), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 15/51 (29%), Positives = 27/51 (52%), Gaps = 5/51 (9%)
 Frame = +3

Query: 191 RKVFVGRCTEDMTAEELQQFFCQYGEVVDVFIPKPF-----RAFAFVTFAD 236
           RK+FVG  + +  ++ L+++F ++GEV    +         R F FV F +
Sbjct: 240 RKIFVGGLSWETXSKHLREYFEKFGEVTSCTLKTDLDSGKSRGFGFVVFKE 392
>19868
          Length = 434

 Score = 85.5 bits (210), Expect = 3e-17,   Method: Compositional matrix adjust.
 Identities = 48/137 (35%), Positives = 79/137 (57%), Gaps = 7/137 (5%)
 Frame = +2

Query: 106 LIVLGLPWKTTEQDLKDYFSTFGEVLMVQVKKDLKTGHSKGFGFVRFTEYETQVKVMSQ- 164
           + V GL W+T+ + L+DYF+ FGE+  V V KD  T  S+GFGF+ F +  +  KV++Q 
Sbjct: 5   MFVGGLSWQTSPESLRDYFNKFGEITEVMVMKDPTTRRSRGFGFITFGDPASVDKVLAQA 184

Query: 165 RHMIDGRWCDCKLPNSKQS-PDEPLRSRKVFVGRCTEDMTAEELQQFFCQYGEVVDVFI- 222
            H +DG+  D K+   +++ P    R++K+FVG  +   T E+++ +F Q+G + D  + 
Sbjct: 185 THELDGKKIDPKVAFPRRAHPRMVTRTKKIFVGGLSAPTTLEDVKNYFEQFGPIEDAMLM 364

Query: 223 ----PKPFRAFAFVTFA 235
                   R F FVT +
Sbjct: 365 FDKQTNRHRGFGFVTIS 415

 Score = 41.6 bits (96), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 21/53 (39%), Positives = 30/53 (56%)
 Frame = +2

Query: 98  RAVQKTSDLIVLGLPWKTTEQDLKDYFSTFGEVLMVQVKKDLKTGHSKGFGFV 150
           R V +T  + V GL   TT +D+K+YF  FG +    +  D +T   +GFGFV
Sbjct: 248 RMVTRTKKIFVGGLSAPTTLEDVKNYFEQFGPIEDAMLMFDKQTNRHRGFGFV 406

 Score = 35.8 bits (81), Expect = 0.035,   Method: Compositional matrix adjust.
 Identities = 26/90 (28%), Positives = 41/90 (45%), Gaps = 9/90 (10%)
 Frame = +2

Query: 192 KVFVGRCTEDMTAEELQQFFCQYGEVVDVFIPKP-----FRAFAFVTFAD----DKVAQS 242
           K+FVG  +   + E L+ +F ++GE+ +V + K       R F F+TF D    DKV   
Sbjct: 2   KMFVGGLSWQTSPESLRDYFNKFGEITEVMVMKDPTTRRSRGFGFITFGDPASVDKVLAQ 181

Query: 243 LCGEDLIIKGISVHISNAEPKHNSNRQLER 272
              E   + G  +    A P+    R + R
Sbjct: 182 ATHE---LDGKKIDPKVAFPRRAHPRMVTR 262
>03000
          Length = 778

 Score = 84.0 bits (206), Expect = 9e-17,   Method: Compositional matrix adjust.
 Identities = 55/170 (32%), Positives = 93/170 (54%), Gaps = 10/170 (5%)
 Frame = +3

Query: 106 LIVLGLPWKTTEQDLKDYFSTFGEVLMVQVKKDLKTGHSKGFGFVRFTEYETQVKVMSQR 165
           L + GL ++T E  L+ +F T+GE++   V +D  +  S+GFGF+ + + E+  +  + R
Sbjct: 93  LFIGGLSYETDEDSLRSHFETWGEIVDCIVMRDSNSKRSRGFGFITYKDAESIDQAQANR 272

Query: 166 -HMIDGRWCDCK--LPNSKQSPDEPLRS-RKVFVGRCTEDMTAEELQQFFCQYGEV--VD 219
            H IDGR  D K  +P  +    E  +S +K+FVG   ED T + ++  F ++GE+  VD
Sbjct: 273 PHKIDGREVDTKRAMPREESGRSEVQQSVKKMFVGGVKEDTTEDMIRDTFNEFGEITGVD 452

Query: 220 VFIPK---PFRAFAFVTFAD-DKVAQSLCGEDLIIKGISVHISNAEPKHN 265
           +   K     R F FVTF D D V +++  +   + G  V +  A+ K++
Sbjct: 453 LIQDKGTGKNRGFCFVTFGDHDSVDKAVLKKRHDLNGRQVEVKKAQSKND 602

 Score = 55.8 bits (133), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 36/103 (34%), Positives = 61/103 (59%), Gaps = 1/103 (0%)
 Frame = +3

Query: 80  DNKRKMDETDASSAVKVKRAVQKTSDLIVLGLPWKTTEQDLKDYFSTFGEVLMVQVKKDL 139
           D KR M   + S   +V+++V+K   + V G+   TTE  ++D F+ FGE+  V + +D 
Sbjct: 300 DTKRAM-PREESGRSEVQQSVKK---MFVGGVKEDTTEDMIRDTFNEFGEITGVDLIQDK 467

Query: 140 KTGHSKGFGFVRFTEYETQVK-VMSQRHMIDGRWCDCKLPNSK 181
            TG ++GF FV F ++++  K V+ +RH ++GR  + K   SK
Sbjct: 468 GTGKNRGFCFVTFGDHDSVDKAVLKKRHDLNGRQVEVKKAQSK 596

 Score = 38.9 bits (89), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 24/84 (28%), Positives = 39/84 (46%), Gaps = 6/84 (7%)
 Frame = +3

Query: 191 RKVFVGRCTEDMTAEELQQFFCQYGEVVDVFI-----PKPFRAFAFVTFAD-DKVAQSLC 244
           RK+F+G  + +   + L+  F  +GE+VD  +      K  R F F+T+ D + + Q+  
Sbjct: 87  RKLFIGGLSYETDEDSLRSHFETWGEIVDCIVMRDSNSKRSRGFGFITYKDAESIDQAQA 266

Query: 245 GEDLIIKGISVHISNAEPKHNSNR 268
                I G  V    A P+  S R
Sbjct: 267 NRPHKIDGREVDTKRAMPREESGR 338
>31618
          Length = 716

 Score = 66.6 bits (161), Expect(2) = 2e-14,   Method: Compositional matrix adjust.
 Identities = 32/79 (40%), Positives = 50/79 (63%), Gaps = 1/79 (1%)
 Frame = +1

Query: 99  AVQKTSDLIVLGLPWKTTEQDLKDYFSTFGEVLMVQVKKDLKTGHSKGFGFVRFTEYETQ 158
           +V  T  L V GL W+TTE++L+D+F  +GE+  + VK D +TG S+GF F+ FT  E  
Sbjct: 277 SVMMTEKLFVGGLSWETTEKELRDHFGKYGEIESINVKTDPQTGRSRGFAFIVFTNTEAI 456

Query: 159 VKV-MSQRHMIDGRWCDCK 176
            +V  ++ H+I+ +  D K
Sbjct: 457 DQVSAAEEHIINSKKVDPK 513

 Score = 30.4 bits (67), Expect(2) = 2e-14,   Method: Compositional matrix adjust.
 Identities = 11/28 (39%), Positives = 20/28 (71%)
 Frame = +3

Query: 189 RSRKVFVGRCTEDMTAEELQQFFCQYGE 216
           R  K+FVG  T +++ EE++ +F Q+G+
Sbjct: 528 RHGKIFVGGLTTEISDEEIKTYFSQFGQ 611

 Score = 35.8 bits (81), Expect = 0.033,   Method: Compositional matrix adjust.
 Identities = 31/114 (27%), Positives = 52/114 (45%), Gaps = 20/114 (17%)
 Frame = +1

Query: 162 MSQRHMIDGRWCDCKLPNSKQSPD--------EPLR------SRKVFVGRCTEDMTAEEL 207
           +S R +    W   K+ N    P         +PLR      + K+FVG  + + T +EL
Sbjct: 163 ISLRMLPPTTWRTLKMENRLPLPALQMAAQKMQPLRVTSVMMTEKLFVGGLSWETTEKEL 342

Query: 208 QQFFCQYGEVVDVFI---PKPFRA--FAFVTFAD-DKVAQSLCGEDLIIKGISV 255
           +  F +YGE+  + +   P+  R+  FAF+ F + + + Q    E+ II    V
Sbjct: 343 RDHFGKYGEIESINVKTDPQTGRSRGFAFIVFTNTEAIDQVSAAEEHIINSKKV 504
>11019
          Length = 552

 Score = 68.2 bits (165), Expect = 6e-12,   Method: Compositional matrix adjust.
 Identities = 45/163 (27%), Positives = 73/163 (44%), Gaps = 28/163 (17%)
 Frame = -1

Query: 110 GLPWKTTEQDLKDYFSTFGEVLMVQVKKDLKTGHSKGFGFVRFTEYETQVKVMSQ-RHMI 168
           GL W+TT + L+ YF  FGE+    V KD  +  S+GFGFV + +      V++   H I
Sbjct: 546 GLSWQTTTETLRSYFEKFGEIKESMVMKDPTSKRSRGFGFVTYKDPSNVDNVLANGPHCI 367

Query: 169 DGRWCDCK-----------LPN-----------SKQSPDEPLRSRKVFVGRCTEDMTAEE 206
           D +  +             LP             K +P    +++K+FVG  +   T E+
Sbjct: 366 DSKTLNFSNMTTFYSNQDLLPYPPQVDPKVAFPRKSNPRMVTKTKKIFVGGLSSSTTVED 187

Query: 207 LQQFFCQYGEVVDVF-----IPKPFRAFAFVTFADDKVAQSLC 244
           ++ +F  YG + +       +    R FAFVTF ++     +C
Sbjct: 186 IKNYFKAYGTIEEATLMFDKVTSRHRGFAFVTFDNESTVDKVC 58

 Score = 44.7 bits (104), Expect = 8e-05,   Method: Compositional matrix adjust.
 Identities = 27/80 (33%), Positives = 38/80 (47%), Gaps = 1/80 (1%)
 Frame = -1

Query: 98  RAVQKTSDLIVLGLPWKTTEQDLKDYFSTFGEVLMVQVKKDLKTGHSKGFGFVRFTEYET 157
           R V KT  + V GL   TT +D+K+YF  +G +    +  D  T   +GF FV F    T
Sbjct: 252 RMVTKTKKIFVGGLSSSTTVEDIKNYFKAYGTIEEATLMFDKVTSRHRGFAFVTFDNEST 73

Query: 158 QVKVMS-QRHMIDGRWCDCK 176
             KV     H I+ +  + K
Sbjct: 72  VDKVCEIHFHEINSKMVETK 13
>26197
          Length = 1365

 Score = 62.0 bits (149), Expect = 5e-10,   Method: Compositional matrix adjust.
 Identities = 32/78 (41%), Positives = 46/78 (58%), Gaps = 1/78 (1%)
 Frame = -2

Query: 106  LIVLGLPWKTTEQDLKDYFSTFGEVLMVQVKKDLKTGHSKGFGFVRFTEYET-QVKVMSQ 164
            + V GL W+T+ + L++YF  FGEV    +K DL +G S+GFGFV F E  T    V ++
Sbjct: 1292 IFVGGLSWETSSKHLREYFEKFGEVTSCTLKTDLDSGKSRGFGFVVFKEAVTVDAVVKNK 1113

Query: 165  RHMIDGRWCDCKLPNSKQ 182
             H + GR  D K  N ++
Sbjct: 1112 EHKLQGRKIDPKPANPRK 1059

 Score = 33.9 bits (76), Expect = 0.12,   Method: Compositional matrix adjust.
 Identities = 21/63 (33%), Positives = 35/63 (55%), Gaps = 1/63 (1%)
 Frame = -3

Query: 110  GLPWKTTEQDLKDYFSTFGEVLMVQVKKDLKTGHSKGFGFVRFTEYETQVKVMSQ-RHMI 168
            G+P    ++D++ YF+ FG+V+ V++  D      + F FV F   +T  KV+ Q  H I
Sbjct: 1021 GVP----QEDVESYFAKFGKVVNVELPYDKVKDQRRAFCFVEFDNDKTVKKVLEQTSHKI 854

Query: 169  DGR 171
             G+
Sbjct: 853  GGQ 845

 Score = 32.7 bits (73), Expect = 0.30,   Method: Compositional matrix adjust.
 Identities = 15/51 (29%), Positives = 28/51 (54%), Gaps = 5/51 (9%)
 Frame = -2

Query: 191  RKVFVGRCTEDMTAEELQQFFCQYGEVVDVFIPKPF-----RAFAFVTFAD 236
            RK+FVG  + + +++ L+++F ++GEV    +         R F FV F +
Sbjct: 1298 RKIFVGGLSWETSSKHLREYFEKFGEVTSCTLKTDLDSGKSRGFGFVVFKE 1146
>32386
          Length = 674

 Score = 57.8 bits (138), Expect = 9e-09,   Method: Compositional matrix adjust.
 Identities = 33/95 (34%), Positives = 55/95 (57%), Gaps = 4/95 (4%)
 Frame = +1

Query: 106 LIVLGLPWKTTEQDLKDYFSTFGEVLMVQVKKDLKTGHSKGFGFVRFTEYETQVKVMSQR 165
           L + GL ++T E  L+ +F T+GE++   V +D  +  S+GFGF+ + + E+  +  + R
Sbjct: 307 LFIGGLSYETDEDSLRSHFETWGEIVDCIVMRDSNSKRSRGFGFITYKDAESIDQAQANR 486

Query: 166 -HMIDGRWCDCK--LPNSKQSPDEPLRS-RKVFVG 196
            H IDGR  D K  +P  +    E  +S +K+FVG
Sbjct: 487 PHKIDGREVDTKRAMPREESGRSEVQQSVKKMFVG 591

 Score = 39.7 bits (91), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 24/84 (28%), Positives = 39/84 (46%), Gaps = 6/84 (7%)
 Frame = +1

Query: 191 RKVFVGRCTEDMTAEELQQFFCQYGEVVDVFI-----PKPFRAFAFVTFAD-DKVAQSLC 244
           RK+F+G  + +   + L+  F  +GE+VD  +      K  R F F+T+ D + + Q+  
Sbjct: 301 RKLFIGGLSYETDEDSLRSHFETWGEIVDCIVMRDSNSKRSRGFGFITYKDAESIDQAQA 480

Query: 245 GEDLIIKGISVHISNAEPKHNSNR 268
                I G  V    A P+  S R
Sbjct: 481 NRPHKIDGREVDTKRAMPREESGR 552
>16016
          Length = 1364

 Score = 56.2 bits (134), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 33/113 (29%), Positives = 56/113 (49%), Gaps = 1/113 (0%)
 Frame = -2

Query: 100  VQKTSDLIVLGLPWKTTEQDLKDYFSTFGEVLMVQVKKDLKTGHSKGFGFVRFTEYETQV 159
             ++   + + G+   T E  L+ YF  +G++    V KD  T  S+ F F+ F   E   
Sbjct: 1321 AERNRKVFIGGMHPDTDESSLRSYFEKYGDIRECIVVKDPATKRSRCFSFITFGNAENVD 1142

Query: 160  KVMSQR-HMIDGRWCDCKLPNSKQSPDEPLRSRKVFVGRCTEDMTAEELQQFF 211
            +V   R H IDGR  + K    ++  +   +++K+FVG   +D T E L++ F
Sbjct: 1141 EVQKDRPHTIDGRTVETKRAMPREDTENHHQTKKMFVGGLKDDTTEEMLRKEF 983

 Score = 37.7 bits (86), Expect = 0.009,   Method: Compositional matrix adjust.
 Identities = 23/84 (27%), Positives = 41/84 (48%), Gaps = 6/84 (7%)
 Frame = -2

Query: 189  RSRKVFVGRCTEDMTAEELQQFFCQYGEVVDVFI-----PKPFRAFAFVTFAD-DKVAQS 242
            R+RKVF+G    D     L+ +F +YG++ +  +      K  R F+F+TF + + V + 
Sbjct: 1315 RNRKVFIGGMHPDTDESSLRSYFEKYGDIRECIVVKDPATKRSRCFSFITFGNAENVDEV 1136

Query: 243  LCGEDLIIKGISVHISNAEPKHNS 266
                   I G +V    A P+ ++
Sbjct: 1135 QKDRPHTIDGRTVETKRAMPREDT 1064
>23322
          Length = 471

 Score = 54.3 bits (129), Expect = 8e-08,   Method: Compositional matrix adjust.
 Identities = 32/92 (34%), Positives = 56/92 (60%), Gaps = 1/92 (1%)
 Frame = -2

Query: 91  SSAVKVKRAVQKTSDLIVLGLPWKTTEQDLKDYFSTFGEVLMVQVKKDLKTGHSKGFGFV 150
           S   +V+++V+K   + V G+   TTE  ++D F+ FGE+  V + +D  TG ++GF FV
Sbjct: 440 SGRSEVQQSVKK---MFVGGVKEDTTEDMIRDTFNEFGEITGVDLIQDKGTGKNRGFCFV 270

Query: 151 RFTEYETQVK-VMSQRHMIDGRWCDCKLPNSK 181
            F ++++  K V+ +RH ++GR  + K   SK
Sbjct: 269 TFGDHDSVDKAVLKKRHDLNGRQVEVKKAQSK 174

 Score = 40.8 bits (94), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 29/96 (30%), Positives = 50/96 (52%), Gaps = 7/96 (7%)
 Frame = -2

Query: 177 LPNSKQSPDEPLRS-RKVFVGRCTEDMTAEELQQFFCQYGEV--VDVFIPK---PFRAFA 230
           +P  +    E  +S +K+FVG   ED T + ++  F ++GE+  VD+   K     R F 
Sbjct: 455 MPREESGRSEVQQSVKKMFVGGVKEDTTEDMIRDTFNEFGEITGVDLIQDKGTGKNRGFC 276

Query: 231 FVTFAD-DKVAQSLCGEDLIIKGISVHISNAEPKHN 265
           FVTF D D V +++  +   + G  V +  A+ K++
Sbjct: 275 FVTFGDHDSVDKAVLKKRHDLNGRQVEVKKAQSKND 168
>02415
          Length = 2763

 Score = 50.8 bits (120), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 25/75 (33%), Positives = 41/75 (54%), Gaps = 1/75 (1%)
 Frame = -1

Query: 104  SDLIVLGLPWKTTEQDLKDYFSTFGEVLMVQVKKDLKTGHSKGFGFVRFTEYETQVKVMS 163
            + + V GLP+ TT+  L++YF  FG++    V  D +TG S+G+GFV   +     +   
Sbjct: 1926 TKIFVGGLPYHTTDHSLREYFDKFGDIDEAVVITDRQTGKSRGYGFVTMADRTGADRACK 1747

Query: 164  QRH-MIDGRWCDCKL 177
              + +IDGR  +  L
Sbjct: 1746 DPNPIIDGRKANVNL 1702
>24983
          Length = 433

 Score = 50.1 bits (118), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 24/69 (34%), Positives = 38/69 (55%), Gaps = 1/69 (1%)
 Frame = -2

Query: 110 GLPWKTTEQDLKDYFSTFGEVLMVQVKKDLKTGHSKGFGFVRFTEYETQVKVMSQRH-MI 168
           GLP+ TT+  L++YF  FG++    V  D +TG S+G+GFV   +     +     + +I
Sbjct: 297 GLPYHTTDHSLREYFDKFGDIDEAVVITDRQTGKSRGYGFVTMADRTGADRACKDPNPII 118

Query: 169 DGRWCDCKL 177
           DGR  +  L
Sbjct: 117 DGRKANVNL 91
>33516
          Length = 449

 Score = 48.5 bits (114), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 24/60 (40%), Positives = 35/60 (58%)
 Frame = +1

Query: 106 LIVLGLPWKTTEQDLKDYFSTFGEVLMVQVKKDLKTGHSKGFGFVRFTEYETQVKVMSQR 165
           + V GL W T +  L+ YFS FGE+    V  + +TG S+GFGFV F +  T   ++S +
Sbjct: 160 IFVGGLSWDTDQDSLQGYFSQFGEITDCIVMMNQQTGKSRGFGFVSFKDPSTVDVILSSK 339

 Score = 36.6 bits (83), Expect = 0.018,   Method: Compositional matrix adjust.
 Identities = 22/65 (33%), Positives = 32/65 (49%), Gaps = 7/65 (10%)
 Frame = +1

Query: 179 NSKQSPDEPLRSR--KVFVGRCTEDMTAEELQQFFCQYGEVVDVFI-----PKPFRAFAF 231
           NSK+  +   R    K+FVG  + D   + LQ +F Q+GE+ D  +         R F F
Sbjct: 112 NSKKQFNMGGREEPGKIFVGGLSWDTDQDSLQGYFSQFGEITDCIVMMNQQTGKSRGFGF 291

Query: 232 VTFAD 236
           V+F D
Sbjct: 292 VSFKD 306
>25691
          Length = 768

 Score = 47.0 bits (110), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 25/72 (34%), Positives = 42/72 (58%), Gaps = 3/72 (4%)
 Frame = -2

Query: 102 KTSDLIVLGLPWKTTEQDLKDYFSTFGEVLMVQVKKDLKTGHSKGFGFVRF---TEYETQ 158
           K ++L + GLP   T+ DL++ F+  G ++  ++  D  TG SKG GF+RF    E E  
Sbjct: 266 KGANLYISGLPKSLTQLDLENLFTDCGNIITSRILYDQTTGLSKGVGFIRFDQRIEAERA 87

Query: 159 VKVMSQRHMIDG 170
           ++ ++  H+ DG
Sbjct: 86  IQKLNN-HIPDG 54
>00302
          Length = 927

 Score = 43.9 bits (102), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 26/68 (38%), Positives = 35/68 (51%), Gaps = 2/68 (2%)
 Frame = -1

Query: 106 LIVLGLPWKTTEQDLKDYFSTFGEVLMVQVKKDLKTGHSKGFGFVRFTEYET--QVKVMS 163
           L + GL   T E+ L++ F  +G +  VQV  D +TG S+GF FV F   E   + K   
Sbjct: 459 LGIFGLSLYTQERGLREVFGRYGHISEVQVVYDRQTGRSRGFAFVYFKSSEDAHEAKDRC 280

Query: 164 QRHMIDGR 171
               IDGR
Sbjct: 279 NGIEIDGR 256
>30672
          Length = 877

 Score = 42.7 bits (99), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 25/68 (36%), Positives = 38/68 (55%), Gaps = 1/68 (1%)
 Frame = +3

Query: 97  KRAVQKTSDLIVLGLPWKTTEQDLKDYFSTFGEVLMVQVKKDLKTG-HSKGFGFVRFTEY 155
           K+ + K   LI+  L +K  E D++ +F  FG +  V +   LK G  S+GF FV+FTE 
Sbjct: 384 KQELGKRCRLIIRNLAFKCKEADIRSHFGKFGTISEVTI--PLKQGDRSRGFAFVQFTEV 557

Query: 156 ETQVKVMS 163
           +   K +S
Sbjct: 558 KAAQKAIS 581

 Score = 37.4 bits (85), Expect = 0.012,   Method: Compositional matrix adjust.
 Identities = 21/83 (25%), Positives = 39/83 (46%)
 Frame = +3

Query: 101 QKTSDLIVLGLPWKTTEQDLKDYFSTFGEVLMVQVKKDLKTGHSKGFGFVRFTEYETQVK 160
           +++  L V  LP++T+ + L + F   G +    V    + G  +GFG+V+F+  E  +K
Sbjct: 3   RQSKTLFVRNLPFETSNEKLLEAFEQVGPLKTAFVVAGKEPGKCRGFGYVQFSMLEDAIK 182

Query: 161 VMSQRHMIDGRWCDCKLPNSKQS 183
                    GR       ++K+S
Sbjct: 183 AKDTVTHCSGRKISLSFADTKKS 251
>35180
          Length = 2181

 Score = 42.7 bits (99), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 26/88 (29%), Positives = 46/88 (52%), Gaps = 6/88 (6%)
 Frame = -2

Query: 167 MIDGRWCDCK-LPNSKQSPDEPLRSRKVFVGRCTEDMTAEELQQFFCQYGEVVDVFI--- 222
           M   R C  K LP++ +   + + SR V+V    ED+T + L +FF Q+G++  + +   
Sbjct: 335 MTKIRRCPSKPLPDNTKERKDDINSRSVYVKGFPEDITLDTLMEFFEQHGKIDTILMRRN 156

Query: 223 --PKPFRAFAFVTFADDKVAQSLCGEDL 248
              K F+   FVTF++ +      G+D+
Sbjct: 155 RPDKNFKGSVFVTFSNKEEEDVFLGKDV 72
>01937
          Length = 1320

 Score = 42.4 bits (98), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 25/65 (38%), Positives = 32/65 (49%)
 Frame = -1

Query: 97   KRAVQKTSDLIVLGLPWKTTEQDLKDYFSTFGEVLMVQVKKDLKTGHSKGFGFVRFTEYE 156
            K  V KTS + V GL   TT +D K+YF  +G +    +  D  T   +GF FV F    
Sbjct: 1236 KTMVTKTSKIFVGGLSSSTTVEDXKNYFKAYGTIEEATLMFDKVTSRHRGFAFVTFDNES 1057

Query: 157  TQVKV 161
            T  KV
Sbjct: 1056 TVDKV 1042

 Score = 39.7 bits (91), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 27/107 (25%), Positives = 46/107 (42%), Gaps = 6/107 (5%)
 Frame = -1

Query: 144  SKGFGFVRFTEYETQVKVMSQR-HMIDGRWCDCKLPNSKQSPDEPLRSRKVFVGRCTEDM 202
            ++GFGFV + +      V++   H ID +    K             + K+FVG  +   
Sbjct: 1320 TRGFGFVTYKDPSNVDNVLANGPHCIDSKTMVTK-------------TSKIFVGGLSSST 1180

Query: 203  TAEELQQFFCQYGEVVDVF-----IPKPFRAFAFVTFADDKVAQSLC 244
            T E+ + +F  YG + +       +    R FAFVTF ++     +C
Sbjct: 1179 TVEDXKNYFKAYGTIEEATLMFDKVTSRHRGFAFVTFDNESTVDKVC 1039
>23250
          Length = 1617

 Score = 41.2 bits (95), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 27/75 (36%), Positives = 42/75 (56%), Gaps = 3/75 (4%)
 Frame = -1

Query: 81   NKRKMDETDASSAVKVKRAVQKTSD--LIVLG-LPWKTTEQDLKDYFSTFGEVLMVQVKK 137
            NKR+ D      + K K+A  + SD  ++ LG +P    E  +K +FS FG V  +++ +
Sbjct: 1395 NKRRED------SQKNKKAKGRKSDRGVVYLGHIPAGFYEPQMKRFFSQFGRVTRLRLSR 1234

Query: 138  DLKTGHSKGFGFVRF 152
              KTG SKG+ F+ F
Sbjct: 1233 STKTGGSKGYAFLEF 1189
>20488
          Length = 3281

 Score = 40.8 bits (94), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 28/87 (32%), Positives = 41/87 (47%)
 Frame = +2

Query: 66   AGWGNLVYVVNYPKDNKRKMDETDASSAVKVKRAVQKTSDLIVLGLPWKTTEQDLKDYFS 125
            AG   LV   ++P     +     A+SA K        ++L +  LP +  +QDL   F 
Sbjct: 2597 AGLSGLVNQASFPNAFNPQAQMQQANSAGKHSEG-PDGANLFIYHLPQEFGDQDLMQMFM 2773

Query: 126  TFGEVLMVQVKKDLKTGHSKGFGFVRF 152
             FG V+  +V  D +T  SK FGFV +
Sbjct: 2774 PFGNVVSAKVFIDKQTNLSKCFGFVSY 2854
>05273
          Length = 1009

 Score = 40.4 bits (93), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 17/39 (43%), Positives = 25/39 (64%)
 Frame = -1

Query: 112 PWKTTEQDLKDYFSTFGEVLMVQVKKDLKTGHSKGFGFV 150
           P  TT+  L++YF  FG++    V  D +TG S+G+GFV
Sbjct: 175 PIITTDHSLREYFDKFGDIDEAVVITDRQTGKSRGYGFV 59
>14637
          Length = 455

 Score = 40.0 bits (92), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 24/80 (30%), Positives = 38/80 (47%)
 Frame = -1

Query: 73  YVVNYPKDNKRKMDETDASSAVKVKRAVQKTSDLIVLGLPWKTTEQDLKDYFSTFGEVLM 132
           Y  ++P     +M +  A+   +        S+L +  LP +  +QDL   F  FG V+ 
Sbjct: 284 YTASFPNAFNNQMQQNAAAKQSEGPDG----SNLFIYHLPQEFGDQDLMQMFMPFGNVIS 117

Query: 133 VQVKKDLKTGHSKGFGFVRF 152
            +V  D +T  SK FGFV +
Sbjct: 116 AKVFIDKQTNLSKCFGFVSY 57
>20169
          Length = 1364

 Score = 40.0 bits (92), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 23/72 (31%), Positives = 38/72 (52%), Gaps = 4/72 (5%)
 Frame = -1

Query: 192  KVFVGRCTEDMTAEELQQFFCQYGEVVDVFIPKPFRAFAFVTFADDKVA----QSLCGED 247
            KV+VG        +EL+  F +YG + +V++ +    FAFV F D++ A    Q+L G  
Sbjct: 1067 KVYVGELGHGCAKQELEDKFAKYGPLKNVWVARRPAGFAFVEFEDNRDAEDAVQALDGAR 888

Query: 248  LIIKGISVHISN 259
            +  +   V +SN
Sbjct: 887  INGRRARVEMSN 852
>23720
          Length = 739

 Score = 39.3 bits (90), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 21/66 (31%), Positives = 35/66 (53%), Gaps = 6/66 (9%)
 Frame = -1

Query: 192 KVFVGRCTEDMTAEELQQFFCQYGEVVDVFIPKPFRAFAFVTF--ADDKV----AQSLCG 245
           +V++GR       +++++FF  YG V D+ +   +    F  F  ADD V     + LCG
Sbjct: 682 RVYIGRLPYQAREKDIERFFRGYGRVNDIMLKNGYGFVEFEDFRDADDAVYELNGKDLCG 503

Query: 246 EDLIIK 251
           E +II+
Sbjct: 502 ERVIIE 485
>04988
          Length = 705

 Score = 39.3 bits (90), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 21/66 (31%), Positives = 35/66 (53%), Gaps = 6/66 (9%)
 Frame = -3

Query: 192 KVFVGRCTEDMTAEELQQFFCQYGEVVDVFIPKPFRAFAFVTF--ADDKV----AQSLCG 245
           +V++GR       +++++FF  YG V D+ +   +    F  F  ADD V     + LCG
Sbjct: 649 RVYIGRLPYQAREKDIERFFRGYGRVNDIMLKNGYGFVEFEDFRDADDAVYELNGKDLCG 470

Query: 246 EDLIIK 251
           E +II+
Sbjct: 469 ERVIIE 452
>03744
          Length = 3486

 Score = 38.9 bits (89), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 25/84 (29%), Positives = 39/84 (46%), Gaps = 4/84 (4%)
 Frame = -1

Query: 73   YVVNYPKDNKRKMDETDASSAVKVKRAVQ----KTSDLIVLGLPWKTTEQDLKDYFSTFG 128
            Y  ++P     +     A+SA K     +      ++L +  LP +  +QDL   F  FG
Sbjct: 3321 YAASFPNAFNPQAQMQQANSAGKHSEGPRVPGPDGANLFIYHLPQEFGDQDLMQMFMPFG 3142

Query: 129  EVLMVQVKKDLKTGHSKGFGFVRF 152
             V+  +V  D +T  SK FGFV +
Sbjct: 3141 NVVSAKVFIDKQTNLSKCFGFVSY 3070
>00817
          Length = 2606

 Score = 38.5 bits (88), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 23/84 (27%), Positives = 41/84 (48%), Gaps = 6/84 (7%)
 Frame = -2

Query: 189  RSRKVFVGRCTEDMTAEELQQFFCQYGEVVDVFI-----PKPFRAFAFVTFAD-DKVAQS 242
            R+RKVF+G    D     L+ +F +YG++ +  +      K  R F+F+TF + + V + 
Sbjct: 2557 RNRKVFIGGMHPDTDESSLRSYFEKYGDIRECIVVKDPATKRSRCFSFITFGNAENVDEV 2378

Query: 243  LCGEDLIIKGISVHISNAEPKHNS 266
                   I G +V    A P+ ++
Sbjct: 2377 QKDRPHTIDGRTVETKRAMPREDT 2306
>17681
          Length = 964

 Score = 38.5 bits (88), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 40/188 (21%), Positives = 73/188 (38%), Gaps = 44/188 (23%)
 Frame = +2

Query: 97  KRAVQKTSDLIVLGLPWKTTEQDLKDYFSTFGEVLMVQVKKDLKTGHSKGFGFVRF---T 153
           K  +     + V  L  +   + L++ F+ FGE+   ++ +D +T  SKG+ FV F    
Sbjct: 11  KTDISSHHHIFVGDLSPEIETETLREAFAPFGEISNCRIVRDPQTMKSKGYAFVSFVKKA 190

Query: 154 EYETQVKVMSQR----HMIDGRWCDCKLPNSKQSPDEPLR-------------------- 189
           E E  ++ M+ +      I   W   KLP  ++S     +                    
Sbjct: 191 EAENAIQAMNGQWIGSRSIRTNWSTRKLPPPRESSKSGGQGGGMGGMGGCGGGAGNGIKN 370

Query: 190 ----------------SRKVFVGRCTEDMTAEEL-QQFFCQYGEVVDVFIPKPFRAFAFV 232
                           +  V+ G    ++ ++EL  + F Q+G + DV + K  + FAF+
Sbjct: 371 NQRHTFEEVYNQSSPTNTTVYCGGFPPNVISDELMHKHFMQFGPIQDVRVFKD-KGFAFI 547

Query: 233 TFADDKVA 240
            F   + A
Sbjct: 548 KFVTKEAA 571
>11126
          Length = 1061

 Score = 38.1 bits (87), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 27/76 (35%), Positives = 38/76 (50%), Gaps = 8/76 (10%)
 Frame = -3

Query: 191 RKVFVGRCTEDMTAEELQQFFCQYGEV------VDVFIPKPFRAFAFVTFAD-DKVAQSL 243
           R V+VG      TAEEL+Q F   G V       D +   P + FA+V FAD D V  + 
Sbjct: 630 RSVYVGNVDYGATAEELEQHFHGCGSVNRVTILCDKYSGHP-KGFAYVEFADKDSVVTAK 454

Query: 244 C-GEDLIIKGISVHIS 258
           C G D + +G  + ++
Sbjct: 453 CTGMDSLFRGRQIKVT 406

 Score = 33.9 bits (76), Expect = 0.12,   Method: Compositional matrix adjust.
 Identities = 16/54 (29%), Positives = 29/54 (53%)
 Frame = -3

Query: 106 LIVLGLPWKTTEQDLKDYFSTFGEVLMVQVKKDLKTGHSKGFGFVRFTEYETQV 159
           + V  + +  T ++L+ +F   G V  V +  D  +GH KGF +V F + ++ V
Sbjct: 624 VYVGNVDYGATAEELEQHFHGCGSVNRVTILCDKYSGHPKGFAYVEFADKDSVV 463
>02343
          Length = 1715

 Score = 38.1 bits (87), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 31/122 (25%), Positives = 51/122 (41%), Gaps = 3/122 (2%)
 Frame = -2

Query: 104  SDLIVLGLPWKTTEQDLKDYFSTFGEVLMVQVKKDLKTGHSKGFGFVRFT---EYETQVK 160
            ++L + GL   TT++DL +    FG +   +   D  T   KG+GFV F      E  V+
Sbjct: 1264 TNLYIRGLSPNTTDKDLVNLCQHFGTITSTKAIIDQTTNKCKGYGFVDFDAPGAAERAVQ 1085

Query: 161  VMSQRHMIDGRWCDCKLPNSKQSPDEPLRSRKVFVGRCTEDMTAEELQQFFCQYGEVVDV 220
             + Q   I  +        +KQ   +P     +++       T + L+  F  YG V+  
Sbjct: 1084 AL-QAQGIQAQM-------AKQQEQDP---TNLYIANLPLHFTEKHLEGLFKDYGTVIST 938

Query: 221  FI 222
             I
Sbjct: 937  RI 932
>15371
          Length = 383

 Score = 37.7 bits (86), Expect = 0.010,   Method: Composition-based stats.
 Identities = 25/80 (31%), Positives = 38/80 (47%)
 Frame = -2

Query: 73  YVVNYPKDNKRKMDETDASSAVKVKRAVQKTSDLIVLGLPWKTTEQDLKDYFSTFGEVLM 132
           Y  ++P     +     A+SA K        ++L +  LP +  +QDL   F  FG V+ 
Sbjct: 247 YAASFPNAFNPQAQMQQANSAGKHSEG-PDGANLFIYHLPQEFGDQDLMQMFMPFGNVVS 71

Query: 133 VQVKKDLKTGHSKGFGFVRF 152
            +V  D +T  SK FGFV +
Sbjct: 70  AKVFIDKQTNLSKCFGFVSY 11
>17775
          Length = 1282

 Score = 37.0 bits (84), Expect = 0.015,   Method: Compositional matrix adjust.
 Identities = 28/109 (25%), Positives = 53/109 (48%), Gaps = 1/109 (0%)
 Frame = -2

Query: 69  GNLVYVVNYPKDNKRKMDETDASSAVKVKRAVQ-KTSDLIVLGLPWKTTEQDLKDYFSTF 127
           G ++Y     K  +R+ +  +    +K++R  + +  +L V  L     ++ L+  FS F
Sbjct: 450 GRIIYCGRAQKRAERQAELKERFEKIKLERINRYQGVNLYVKNLDDSIDDERLRKEFSNF 271

Query: 128 GEVLMVQVKKDLKTGHSKGFGFVRFTEYETQVKVMSQRHMIDGRWCDCK 176
           G +   ++  +   G SKGFGFV F+  E   K +++   ++GR    K
Sbjct: 270 GTITSAKIMTE--GGRSKGFGFVCFSSPEEATKAVTE---MNGRIIVAK 139

 Score = 31.2 bits (69), Expect = 0.85,   Method: Compositional matrix adjust.
 Identities = 34/151 (22%), Positives = 58/151 (38%), Gaps = 22/151 (14%)
 Frame = -2

Query: 142 GHSKGFGFVRFTEYETQVKVMSQRH--MIDGRWCDCKLPNSKQSPDEPLRSR-------- 191
           G S+GFGFV F E E   K + + +   + GR   C     +      L+ R        
Sbjct: 540 GKSRGFGFVSFEEPEGAEKAVDEINGTEVSGRIIYCGRAQKRAERQAELKERFEKIKLER 361

Query: 192 -------KVFVGRCTEDMTAEELQQFFCQYGEVVDVFIPKP---FRAFAFVTFADDKVAQ 241
                   ++V    + +  E L++ F  +G +    I       + F FV F+  + A 
Sbjct: 360 INRYQGVNLYVKNLDDSIDDERLRKEFSNFGTITSAKIMTEGGRSKGFGFVCFSSPEEAT 181

Query: 242 SLCGE--DLIIKGISVHISNAEPKHNSNRQL 270
               E    II    ++++ A+ K +   QL
Sbjct: 180 KAVTEMNGRIIVAKPLYVALAQRKEDRRAQL 88

 Score = 30.0 bits (66), Expect = 1.7,   Method: Compositional matrix adjust.
 Identities = 26/93 (27%), Positives = 39/93 (41%)
 Frame = -2

Query: 105 DLIVLGLPWKTTEQDLKDYFSTFGEVLMVQVKKDLKTGHSKGFGFVRFTEYETQVKVMSQ 164
           ++ +  L      + L D FS FG +L  ++  D +   SKG+GFV F   E      + 
Sbjct: 927 NVFIKNLDKTIDNKALYDTFSAFGNILSCKIACDEQG--SKGYGFVHFETEE------AA 772

Query: 165 RHMIDGRWCDCKLPNSKQSPDEPLRSRKVFVGR 197
           R  ID            +     L  +KV+VGR
Sbjct: 771 RQAID------------KVNGMLLNGKKVYVGR 709
>11108
          Length = 493

 Score = 36.2 bits (82), Expect = 0.025,   Method: Compositional matrix adjust.
 Identities = 18/65 (27%), Positives = 33/65 (50%)
 Frame = -1

Query: 98  RAVQKTSDLIVLGLPWKTTEQDLKDYFSTFGEVLMVQVKKDLKTGHSKGFGFVRFTEYET 157
           R +  +  + + G+PW  +EQ L   F  FG + +    K+ +    KG+ ++ F E + 
Sbjct: 310 RMLNYSPKVFLGGIPWDISEQSLIQIFKPFGSIKVEWPGKEQQAAQPKGYVYIIF-ESDK 134

Query: 158 QVKVM 162
           QVK +
Sbjct: 133 QVKAL 119
>02809
          Length = 1475

 Score = 36.2 bits (82), Expect = 0.025,   Method: Compositional matrix adjust.
 Identities = 17/50 (34%), Positives = 29/50 (58%)
 Frame = -1

Query: 192  KVFVGRCTEDMTAEELQQFFCQYGEVVDVFIPKPFRAFAFVTFADDKVAQ 241
            KV+VG        +EL+  F +YG + +V++ +    FAFV F D++ A+
Sbjct: 1331 KVYVGELGHGCAKQELEDKFAKYGPLKNVWVARRPAGFAFVEFEDNRDAE 1182
>13822
          Length = 963

 Score = 35.0 bits (79), Expect = 0.062,   Method: Compositional matrix adjust.
 Identities = 18/47 (38%), Positives = 27/47 (57%)
 Frame = -1

Query: 106 LIVLGLPWKTTEQDLKDYFSTFGEVLMVQVKKDLKTGHSKGFGFVRF 152
           L V  +P++  E DL+     FG +L V++  + +   SKGFGFV F
Sbjct: 336 LHVSNIPFRFREADLRQLLGPFGTILDVEIIFNER--GSKGFGFVTF 202
>00029
          Length = 2204

 Score = 34.7 bits (78), Expect = 0.064,   Method: Compositional matrix adjust.
 Identities = 23/80 (28%), Positives = 39/80 (48%), Gaps = 5/80 (6%)
 Frame = -3

Query: 192  KVFVGRCTEDMTAEELQQFFCQYGEVVDVFIPKPFRAFAFVTF-----ADDKVAQSLCGE 246
            K+F+G   +D   EEL+  F +YG V +  +    + F FV       ADD ++ +L G 
Sbjct: 2133 KIFIGNLGDDTDPEELRALFEKYGSVAECDV---LKNFGFVHMVKKGEADDAIS-NLNGY 1966

Query: 247  DLIIKGISVHISNAEPKHNS 266
            ++  + + V +S    K  S
Sbjct: 1965 NIGGQRMRVELSTGAGKGGS 1906
>02064
          Length = 1195

 Score = 34.3 bits (77), Expect = 0.086,   Method: Compositional matrix adjust.
 Identities = 23/72 (31%), Positives = 34/72 (47%), Gaps = 2/72 (2%)
 Frame = +1

Query: 108 VLGLPWKTTEQDLKDYFSTFGEVLMVQVKKDLKTGHSKGFGFVRFTEYETQVKVMSQ--R 165
           V  LP+  T QDL++ F   G V   ++  D   G S G G VRF   +  V+ ++   R
Sbjct: 91  VKNLPYAITWQDLRERFQEIGVVKYSEITMD--KGRSTGQGLVRFATEDDAVRAINSMDR 264

Query: 166 HMIDGRWCDCKL 177
              +GR    K+
Sbjct: 265 TRYEGRTIGVKM 300
>00556
          Length = 2189

 Score = 34.3 bits (77), Expect = 0.092,   Method: Compositional matrix adjust.
 Identities = 19/60 (31%), Positives = 30/60 (50%), Gaps = 1/60 (1%)
 Frame = +3

Query: 96  VKRAVQKTSDLIVLG-LPWKTTEQDLKDYFSTFGEVLMVQVKKDLKTGHSKGFGFVRFTE 154
           V   VQ +   I +G LP   +E  +K+   +FG +    + +D  TG SKGF F  + +
Sbjct: 732 VSTVVQDSDHKIFMGGLPSYLSEDQMKELLLSFGPLKSFNLVRDNATGLSKGFAFCEYLD 911
>28605
          Length = 697

 Score = 33.9 bits (76), Expect = 0.11,   Method: Compositional matrix adjust.
 Identities = 17/45 (37%), Positives = 26/45 (57%), Gaps = 1/45 (2%)
 Frame = -3

Query: 192 KVFVGRCTEDMTAE-ELQQFFCQYGEVVDVFIPKPFRAFAFVTFA 235
           +VFV   + D T+E ELQ+ F +YG V+D  +      + FV F+
Sbjct: 566 RVFVANLSSDETSEAELQELFSKYGNVLDTLVHH--NRYGFVQFS 438
>09968
          Length = 2913

 Score = 33.5 bits (75), Expect = 0.16,   Method: Compositional matrix adjust.
 Identities = 24/87 (27%), Positives = 35/87 (40%), Gaps = 7/87 (8%)
 Frame = -1

Query: 90   ASSAVKVK-------RAVQKTSDLIVLGLPWKTTEQDLKDYFSTFGEVLMVQVKKDLKTG 142
            A S V VK       +A     +L V GL   T   DLK  F   G+V+  +V  + ++ 
Sbjct: 1455 AKSGVAVKPAKGKDDKATTSIRNLWVSGLSSSTRATDLKSLFGKHGKVIGAKVVTNTRSP 1276

Query: 143  HSKGFGFVRFTEYETQVKVMSQRHMID 169
                FGFV     +   K +   H  +
Sbjct: 1275 GRLCFGFVTMASADETTKCIQHLHRTE 1195
>02347
          Length = 928

 Score = 33.5 bits (75), Expect = 0.16,   Method: Compositional matrix adjust.
 Identities = 16/49 (32%), Positives = 29/49 (59%)
 Frame = -3

Query: 192 KVFVGRCTEDMTAEELQQFFCQYGEVVDVFIPKPFRAFAFVTFADDKVA 240
           K++VG    D + +E+++ F  YG + +V++ +    FAFV F D + A
Sbjct: 743 KIYVGDLPPDASEKEVERAFNYYGHLRNVWVARNPPGFAFVEFEDTRDA 597
>16427
          Length = 1313

 Score = 32.7 bits (73), Expect = 0.29,   Method: Compositional matrix adjust.
 Identities = 22/70 (31%), Positives = 34/70 (48%), Gaps = 3/70 (4%)
 Frame = +1

Query: 102 KTSDLIVLGLPWKTTEQDLKDYFSTFGEVLMVQVKKDLKTGHSKGFGFVRF---TEYETQ 158
           +   L V GL  +  E+ L+  FS FG +    V +D     S+GFGFV +    + E  
Sbjct: 130 RPGKLFVGGLAEEIDEKVLEREFSKFGRITESMVIRDKVRQVSRGFGFVTYENPMDAEEA 309

Query: 159 VKVMSQRHMI 168
           VK M  + ++
Sbjct: 310 VKHMDGKEIL 339
>08958
          Length = 680

 Score = 32.0 bits (71), Expect = 0.52,   Method: Compositional matrix adjust.
 Identities = 18/71 (25%), Positives = 36/71 (50%), Gaps = 2/71 (2%)
 Frame = +2

Query: 192 KVFVGRCTEDMTAEELQQFFCQYGEVVDVFIPKPFRAFAFVT--FADDKVAQSLCGEDLI 249
           ++FVG  T D++ ++ ++ F  +GEV + ++    R F F+   +  +  A     + L 
Sbjct: 71  RLFVGNLTPDVSEDDFKKLFSPFGEVSEAYVNSG-RGFGFIRLDYRHNAEAAKAALDGLQ 247

Query: 250 IKGISVHISNA 260
            KG S+ +  A
Sbjct: 248 RKGRSLRVRYA 280
>23655
          Length = 929

 Score = 31.6 bits (70), Expect = 0.56,   Method: Compositional matrix adjust.
 Identities = 15/42 (35%), Positives = 25/42 (59%)
 Frame = -1

Query: 106 LIVLGLPWKTTEQDLKDYFSTFGEVLMVQVKKDLKTGHSKGF 147
           + V G+   TTE  ++D F+ FGE+  V + +D  TG ++ F
Sbjct: 899 MFVGGVKEDTTEDMIRDTFNEFGEITGVDLIQDKGTGKNRDF 774

 Score = 28.5 bits (62), Expect = 4.8,   Method: Compositional matrix adjust.
 Identities = 14/38 (36%), Positives = 22/38 (57%), Gaps = 4/38 (10%)
 Frame = -1

Query: 187 PLRS----RKVFVGRCTEDMTAEELQQFFCQYGEVVDV 220
           P+RS     K+FVG   ED T + ++  F ++GE+  V
Sbjct: 929 PIRSSTVREKMFVGGVKEDTTEDMIRDTFNEFGEITGV 816
>14258
          Length = 1063

 Score = 31.6 bits (70), Expect = 0.62,   Method: Compositional matrix adjust.
 Identities = 16/36 (44%), Positives = 21/36 (58%)
 Frame = +2

Query: 117 EQDLKDYFSTFGEVLMVQVKKDLKTGHSKGFGFVRF 152
           +QDL   F  FG V+  +V  D +T  SK FGFV +
Sbjct: 101 DQDLMQMFMPFGNVISAKVFIDKQTNLSKCFGFVSY 208
>09736
          Length = 1319

 Score = 30.0 bits (66), Expect = 1.7,   Method: Compositional matrix adjust.
 Identities = 13/30 (43%), Positives = 19/30 (63%)
 Frame = -2

Query: 141  TGHSKGFGFVRFTEYETQVKVMSQRHMIDG 170
            +G SKGFGFVRF+E   Q + + +   + G
Sbjct: 1279 SGKSKGFGFVRFSEENDQQRALVEMQHMTG 1190
>19556
          Length = 917

 Score = 30.0 bits (66), Expect = 1.9,   Method: Compositional matrix adjust.
 Identities = 17/62 (27%), Positives = 31/62 (50%), Gaps = 5/62 (8%)
 Frame = -1

Query: 188 LRSRKVFVGRCTEDMTAEELQQFFCQYGEVVDVFIPK-----PFRAFAFVTFADDKVAQS 242
           L+ ++ F+G   + +T EEL + F ++G+V +V I         R FA+V    ++    
Sbjct: 839 LQRKENFIGGLVKGVTEEELMEKFSRFGQVSNVDIKTRTNGIDSRTFAYVNLTAEENGFK 660

Query: 243 LC 244
            C
Sbjct: 659 KC 654
>12506
          Length = 1056

 Score = 29.3 bits (64), Expect = 3.1,   Method: Compositional matrix adjust.
 Identities = 11/33 (33%), Positives = 19/33 (57%)
 Frame = -3

Query: 120  LKDYFSTFGEVLMVQVKKDLKTGHSKGFGFVRF 152
            L   F  FG+++ +Q+  D +T   +GF F+ F
Sbjct: 1015 LHAAFLPFGDIVDIQIPLDYETEKHRGFAFIEF 917
>25950
          Length = 417

 Score = 28.9 bits (63), Expect = 3.9,   Method: Compositional matrix adjust.
 Identities = 18/78 (23%), Positives = 34/78 (43%), Gaps = 15/78 (19%)
 Frame = -2

Query: 103 TSDLIVLGLPWKTTEQDLKDYFSTFGEVLMVQVKKDLKTGHSKGFGFVRFTEYE------ 156
           T  + V  + +  + ++L+ +F   G +  V +  +   GH KGF ++ F   E      
Sbjct: 284 TRSVYVGNVDYGASAEELEAHFHGCGTINRVTILCNKADGHPKGFAYIEFGSKEYVETAL 105

Query: 157 ---------TQVKVMSQR 165
                     Q+KVM++R
Sbjct: 104 AMNETLFRGRQIKVMTKR 51
>33504
          Length = 282

 Score = 28.9 bits (63), Expect = 4.2,   Method: Composition-based stats.
 Identities = 14/36 (38%), Positives = 21/36 (58%)
 Frame = +1

Query: 185 DEPLRSRKVFVGRCTEDMTAEELQQFFCQYGEVVDV 220
           DE   S  VF+G    D+T  ++   F QYGE+V++
Sbjct: 151 DEYKDSAWVFIGGLPYDLTEGDIICVFSQYGEIVNI 258

 Score = 28.5 bits (62), Expect = 5.0,   Method: Composition-based stats.
 Identities = 11/29 (37%), Positives = 19/29 (65%)
 Frame = +1

Query: 110 GLPWKTTEQDLKDYFSTFGEVLMVQVKKD 138
           GLP+  TE D+   FS +GE++ + + +D
Sbjct: 187 GLPYDLTEGDIICVFSQYGEIVNINLVRD 273
>19246
          Length = 440

 Score = 28.1 bits (61), Expect = 7.6,   Method: Compositional matrix adjust.
 Identities = 11/37 (29%), Positives = 19/37 (51%)
 Frame = -3

Query: 39  CGLRYRNPVSQCMRGVRLVEGILHAPDAGWGNLVYVV 75
           CG    +P+S C+  +R +   L  P + W  L+ V+
Sbjct: 426 CGDACNSPLSDCVLTLRRISSALPMPSSSWSGLLLVL 316
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|20149754|ref|NP_619609.1| UFM1-specific peptidase 2
[Mus musculus]
         (461 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

17875                                                                 352   1e-97
31154                                                                  77   2e-14
33160                                                                  30   1.9  
02203                                                                  30   2.4  
>17875
          Length = 1155

 Score =  352 bits (904), Expect = 1e-97,   Method: Compositional matrix adjust.
 Identities = 162/282 (57%), Positives = 203/282 (71%)
 Frame = -2

Query: 176 ILRYMKGTSIVVPEPLHFQLPGKKNLVTVLYPSGIPDDQLQAYRKELHDLFNLPHDRPYF 235
           ILR M  T      P+HF +P +   +T +YP  I +D L   R+ LH+   LP D+P F
Sbjct: 917 ILRRMSSTH---QSPVHFTIPHRHTCITAVYPRNISEDNLVKRRQYLHEKMCLPLDKPLF 747

Query: 236 KRINAYHFPDELYKDGYIRNPHTYLSPPNIEGSMICVVQGTYAYHHYMQDRIDDNGWGCA 295
           +R N   FP +  + GYI NPH  LSP  + G    VVQG Y+YHHYMQDR DD+ WGCA
Sbjct: 746 RRANTRLFPGQRAEGGYIINPHLGLSPSGVVGGTPHVVQGNYSYHHYMQDRFDDDKWGCA 567

Query: 296 YRSLQTICSWFRHQGYTERSIPTHREIQQALVDAGDKPATFVGSRQWIGSIEVQMVLNQL 355
           YRSLQT+ SWFR QGYT+  +P+HR+IQQALV  GDK ++FVGS++WIGS EV  VL+ L
Sbjct: 566 YRSLQTLVSWFRFQGYTDSPVPSHRDIQQALVAVGDKESSFVGSKKWIGSFEVSFVLDHL 387

Query: 356 IGVTSKILFVNQGSEMASQGRELANHFQNVGTPVMVGGGVLAHTILGVAWNETTGQIKFL 415
           +GVT K L V+ G+E+AS+GRELA HF   GTP+M+GGGVLAHTILGV +NE +G IKFL
Sbjct: 386 LGVTCKFLNVSAGAELASKGRELAQHFDTEGTPIMIGGGVLAHTILGVDYNEMSGDIKFL 207

Query: 416 ILDPHYTGAEDLQVMLEKGWCGWKSPDFWNKDAYYNLCLPQR 457
           ILDPHYTG EDL  + ++GWCGWK P+FWN  A+YN+C+P R
Sbjct: 206 ILDPHYTGGEDLNTIHKEGWCGWKGPEFWNATAHYNMCMPMR 81

 Score = 37.7 bits (86), Expect = 0.009,   Method: Compositional matrix adjust.
 Identities = 22/86 (25%), Positives = 40/86 (46%), Gaps = 1/86 (1%)
 Frame = -1

Query: 117  TPLGAVTPILERENEEHHYINMSLPIDAVVSVAPEESWGKVRKLLVDAILRQLVDVEKCI 176
            T L  + P + +      ++  SLP+DA+V V  ++    ++ L V A+  QL  +  C+
Sbjct: 1107 TLLPHLCPAVHQRTGSFRFLKCSLPLDAIVEVDVKDQVSSLQSLFVTAVTSQLQAMLACL 928

Query: 177  -LRYMKGTSIVVPEPLHFQLPGKKNL 201
             L + K      PEP     P + ++
Sbjct: 927  QLHHSKENEFYTPEPCPLHNPTQTHV 850
>31154
          Length = 422

 Score = 76.6 bits (187), Expect = 2e-14,   Method: Composition-based stats.
 Identities = 41/101 (40%), Positives = 57/101 (56%)
 Frame = +3

Query: 298 SLQTICSWFRHQGYTERSIPTHREIQQALVDAGDKPATFVGSRQWIGSIEVQMVLNQLIG 357
           +LQ  CS       T   +P+  ZIQ+ALV  GDKP  FVGSRQWIGS EV + L+   G
Sbjct: 30  ALQHACS------KTVPDVPSLLZIQRALVRIGDKPDHFVGSRQWIGSYEVCLCLDFFYG 191

Query: 358 VTSKILFVNQGSEMASQGRELANHFQNVGTPVMVGGGVLAH 398
           V  KI+ + QG+++      L  HF    +P+M+G  ++ H
Sbjct: 192 VPCKIIHIKQGADLRQHLSTLQTHFSTKASPIMMGVILMPH 314
>33160
          Length = 788

 Score = 30.0 bits (66), Expect = 1.9,   Method: Compositional matrix adjust.
 Identities = 16/44 (36%), Positives = 22/44 (50%), Gaps = 2/44 (4%)
 Frame = -3

Query: 394 GVLAHTILGVAWNETT--GQIKFLILDPHYTGAEDLQVMLEKGW 435
            VL H   G  W+ T     +  L+LDPHY      +V++EK W
Sbjct: 555 SVLVHCSDG--WDRTAQLTSLAMLMLDPHYRTIRGFEVLVEKEW 430
>02203
          Length = 1671

 Score = 29.6 bits (65), Expect = 2.4,   Method: Compositional matrix adjust.
 Identities = 11/31 (35%), Positives = 17/31 (54%)
 Frame = -3

Query: 48   RVCNSSVYLWPNSDANTGELTDSSACKNVVR 78
            R C +++++WP SD + G    SS C    R
Sbjct: 1585 RFCTNTLWMWPGSDVSFGRSIASSVCWGSFR 1493

 Score = 28.9 bits (63), Expect = 5.1,   Method: Compositional matrix adjust.
 Identities = 11/31 (35%), Positives = 17/31 (54%)
 Frame = -2

Query: 48  RVCNSSVYLWPNSDANTGELTDSSACKNVVR 78
           R C +++++WP SD + G    SS C    R
Sbjct: 521 RFCTNTLWMWPGSDVSFGRSIASSVCWGSFR 429
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6678413|ref|NP_033441.1| triosephosphate isomerase 1
[Mus musculus]
         (249 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

03568                                                                 351   2e-97
07349                                                                  44   5e-05
>03568
          Length = 1712

 Score =  351 bits (901), Expect = 2e-97,   Method: Compositional matrix adjust.
 Identities = 170/245 (69%), Positives = 195/245 (79%)
 Frame = +1

Query: 5   RKFFVGGNWKMNGRKKCLGELICTLNAANVPAGTEVVCAPPTAYIDFARQKLDPKIAVAA 64
           RKFFVGGNWKMNG KK +  +I  L    +   TEVV APPT Y+ +  Q +   + VAA
Sbjct: 85  RKFFVGGNWKMNGNKKSIDGIITFLKDGTLDPNTEVVVAPPTIYLPYVHQNICGTVQVAA 264

Query: 65  QNCYKVTNGAFTGEISPGMIKDLGATWVVLGHSERRHVFGESDELIGQKVSHALAEGLGV 124
           QNCYKV  GAFTGE SP M+KD G +WV+LGHSERRHVFGES+ELIG+K  +AL +GL +
Sbjct: 265 QNCYKVEKGAFTGETSPEMLKDNGISWVILGHSERRHVFGESNELIGEKTKYALEKGLSL 444

Query: 125 IACIGEKLDEREAGITEKVVFEQTKVIADNVKDWSKVVLAYEPVWAIGTGKTATPQQAQE 184
           I CIGEKLDER+AG TE+VVF+Q K IADNV DW +VV+AYEPVWAIGTGKTATP+QAQE
Sbjct: 445 IPCIGEKLDERDAGKTEEVVFKQMKFIADNVSDWKRVVIAYEPVWAIGTGKTATPEQAQE 624

Query: 185 VHEKLRGWLKSNVNDGVAQSTRIIYGGSVTGATCKELASQPDVDGFLVGGASLKPEFVDI 244
           VH+ LR WL  NV+  VAQSTRIIYGGSVT   CKELA +PDVDGFLVGGASLKP+FV I
Sbjct: 625 VHKSLRDWLAKNVSAEVAQSTRIIYGGSVTADNCKELAGKPDVDGFLVGGASLKPDFVKI 804

Query: 245 INAKQ 249
           INAKQ
Sbjct: 805 INAKQ 819
>07349
          Length = 960

 Score = 44.3 bits (103), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 21/24 (87%), Positives = 22/24 (91%)
 Frame = +3

Query: 226 DVDGFLVGGASLKPEFVDIINAKQ 249
           D DGFLVGGASLKP+FV IINAKQ
Sbjct: 18  DGDGFLVGGASLKPDFVKIINAKQ 89
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|7106387|ref|NP_036097.1| proteasome (prosome,
macropain) subunit, alpha type 5 [Mus musculus]
         (241 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

20771                                                                 351   2e-97
02448                                                                 166   1e-41
24591                                                                 165   2e-41
17033                                                                 137   3e-33
00789                                                                 127   3e-30
14551                                                                 127   5e-30
04255                                                                  91   5e-19
19133                                                                  70   1e-12
03425                                                                  42   2e-04
28971                                                                  42   2e-04
01337                                                                  39   0.002
37174                                                                  36   0.015
11023                                                                  33   0.077
00434                                                                  29   1.5  
00497                                                                  27   7.5  
>20771
          Length = 674

 Score =  351 bits (900), Expect = 2e-97,   Method: Compositional matrix adjust.
 Identities = 163/198 (82%), Positives = 182/198 (91%)
 Frame = +2

Query: 1   MFLTRSEYDRGVNTFSPEGRLFQVEYAIEAIKLGSTAIGIQTSEGVCLAVEKRITSPLME 60
           MFLTRSEYDRGVNTFSPEGRLFQVEYAIEAIKLGSTAIGIQT+EGV LAVEKR+TS L+E
Sbjct: 80  MFLTRSEYDRGVNTFSPEGRLFQVEYAIEAIKLGSTAIGIQTNEGVVLAVEKRVTSSLIE 259

Query: 61  PSSIEKIVEIDAHIGCAMSGLIADAKTLIDKARVETQNHWFTYNETMTVESVTQAVSNLA 120
           P+SIEKI+E+D HIGCAMSGLIAD++TLID+ARVE QNHWFTYNE M+VESVTQAVSNLA
Sbjct: 260 PTSIEKIMEVDKHIGCAMSGLIADSRTLIDRARVEAQNHWFTYNENMSVESVTQAVSNLA 439

Query: 121 LQFGEEDADPGAMSRPFGVALLFGGVDEKGPQLFHMDPSGTFVQCDARAIGSASEGAQSS 180
           L FG++D DPGAMSRPFGVALL  GVD  GP+LFHMDPSGTF+Q DA+AIGS SEGAQ +
Sbjct: 440 LAFGDDDPDPGAMSRPFGVALLIAGVDSNGPRLFHMDPSGTFIQYDAKAIGSGSEGAQQA 619

Query: 181 LQEVYHKSMTLKEAIKSS 198
           LQE YHKS+TLK+A KS+
Sbjct: 620 LQEQYHKSITLKDACKSA 673
>02448
          Length = 1302

 Score =  166 bits (419), Expect = 1e-41,   Method: Compositional matrix adjust.
 Identities = 89/234 (38%), Positives = 140/234 (59%), Gaps = 3/234 (1%)
 Frame = +2

Query: 8   YDRGVNTFSPEGRLFQVEYAIEAIKLGSTAIGIQTSEGVCLAVEKRITSPLMEPSSIEKI 67
           YDR +  FSP+G LFQVEYA EA+K GSTA+G++ +  V L VEK+  + L E  ++ KI
Sbjct: 263 YDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGNNLVVLGVEKKAVAKLQEERTVRKI 442

Query: 68  VEIDAHIGCAMSGLIADAKTLIDKARVETQNHWFTYNETMTVESVTQAVSNLALQFGEED 127
             +D H+  A +GL ADA+ LI++AR+E Q+H  T  + +TVE +T+ ++ L  ++ + +
Sbjct: 443 ALLDEHVALAFAGLTADARILINRARIECQSHKLTVEDPVTVEYITRHIAQLKQKYTQSN 622

Query: 128 ADPGAMSRPFGVALLFGGVDEKG-PQLFHMDPSGTFVQCDARAIGSASEGAQSSLQEVYH 186
                  RPFG++ L  G D  G P L+  DPSGT+ +  A  IG  ++  +  L++ Y 
Sbjct: 623 G-----RRPFGLSSLIIGFDYDGSPHLYQTDPSGTYHEWKANTIGRNAKTVREFLEKHYT 787

Query: 187 KSMTL--KEAIKSSLIILKQVMEEKLNATNIELATVQPGQNFHMFTKEELEEVI 238
             +    KE IK +L  L +V++    A N+E+A ++ GQ   M   +E+E+ I
Sbjct: 788 DEVAASDKETIKLALKALLEVVQS--GAKNMEVAVMRRGQALQMLESDEIEKYI 943
>24591
          Length = 1801

 Score =  165 bits (417), Expect = 2e-41,   Method: Compositional matrix adjust.
 Identities = 89/234 (38%), Positives = 139/234 (59%), Gaps = 3/234 (1%)
 Frame = +1

Query: 8   YDRGVNTFSPEGRLFQVEYAIEAIKLGSTAIGIQTSEGVCLAVEKRITSPLMEPSSIEKI 67
           YDR +  FSP+G LFQVEYA EA+K GSTA+G++    V L VEK+  + L E  ++ KI
Sbjct: 40  YDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGDNLVVLGVEKKAVAKLQEERTVRKI 219

Query: 68  VEIDAHIGCAMSGLIADAKTLIDKARVETQNHWFTYNETMTVESVTQAVSNLALQFGEED 127
             +D H+  A +GL ADA+ LI++AR+E Q+H  T  + +TVE +T+ ++ L  ++ + +
Sbjct: 220 ALLDEHVALAFAGLTADARILINRARIECQSHKLTVEDPVTVEYITRHIAQLKQKYTQSN 399

Query: 128 ADPGAMSRPFGVALLFGGVDEKG-PQLFHMDPSGTFVQCDARAIGSASEGAQSSLQEVYH 186
                  RPFG++ L  G D  G P L+  DPSGT+ +  A  IG  ++  +  L++ Y 
Sbjct: 400 G-----RRPFGLSSLIIGFDYDGTPHLYQTDPSGTYHEWKANTIGRNAKTVREFLEKHYT 564

Query: 187 KSMTL--KEAIKSSLIILKQVMEEKLNATNIELATVQPGQNFHMFTKEELEEVI 238
             +    KE IK +L  L +V++    A N+E+A ++ GQ   M   +E+E+ I
Sbjct: 565 DEVAASDKETIKLALKALLEVVQS--GAKNMEVAVMRRGQALQMLESDEIEKYI 720
>17033
          Length = 2217

 Score =  137 bits (346), Expect = 3e-33,   Method: Compositional matrix adjust.
 Identities = 75/214 (35%), Positives = 128/214 (59%), Gaps = 1/214 (0%)
 Frame = -3

Query: 8    YDRGVNTFSPEGRLFQVEYAIEAIKLGSTAIGIQTSEGVCLAVEKRITSPLMEPSSIEKI 67
            YD   + FSP+GR+FQVEYA +A++   TAIGI+  +GV + VEK +TS L E  + +++
Sbjct: 2149 YDLSASHFSPDGRVFQVEYAQKAVENSGTAIGIRGKDGVVMGVEKLVTSKLYEQGANKRL 1970

Query: 68   VEIDAHIGCAMSGLIADAKTLIDKARVETQNHWFTYNETMTVESVTQAVSNLALQFGEED 127
              ID HIG A++GL+ADA+ L+++A+ E+ N+ F Y   + ++ +T  V+     +    
Sbjct: 1969 FNIDRHIGGAVAGLLADARQLMERAKEESSNYRFNYGSPVPLKYLTDRVAGYVHAYTLHS 1790

Query: 128  ADPGAMSRPFGVALLFGGVDEKGPQLFHMDPSGTFVQCDARAIGSASEGAQSSLQEVYHK 187
            A      RPFG +++    D  GPQ+F ++PSG        AIG A + A++ ++++  K
Sbjct: 1789 A-----VRPFGTSMIVASYDAVGPQMFLVEPSGVSWGYYGCAIGKAKQTAKTEIEKLKMK 1625

Query: 188  SMTLKEAIKSSLIILKQVMEE-KLNATNIELATV 220
             +T+++ +K    I+  V +E K  +  +EL+ V
Sbjct: 1624 DLTMQDLVKEVARIIYVVHDEVKDKSFELELSWV 1523
>00789
          Length = 1584

 Score =  127 bits (320), Expect = 3e-30,   Method: Compositional matrix adjust.
 Identities = 79/221 (35%), Positives = 123/221 (55%), Gaps = 7/221 (3%)
 Frame = +1

Query: 7   EYDRGVNTFSPEGRLFQVEYAIEAIKLGSTAIGIQTSEGVCLAVEKRITSPLM-EPSSIE 65
            YD     FSPEGRL+QVEYA+EAI    T +GI   +G+ LA E+R T+ L+ E S  E
Sbjct: 31  RYDSRTTIFSPEGRLYQVEYAMEAIGHAGTCLGILAKDGIVLAAERRNTNKLLDEVSYSE 210

Query: 66  KIVEIDAHIGCAMSGLIADAKTLIDKARVETQNHWFTYNETMTVESVTQAVSNLA---LQ 122
           KI  +   + C+++G+ +DA  L ++ R+  Q +   Y E +  E V   + ++     Q
Sbjct: 211 KIYRLSDDMACSVAGITSDANVLTNELRLIAQRYLLQYQEPIPCEQVVATLCDIKQAYTQ 390

Query: 123 FGEEDADPGAMSRPFGVALLFGGVDEK-GPQLFHMDPSGTFVQCDARAIGSASEGAQSSL 181
           FG +        RPFGV++L+ G D+  G QL+  DPSG +    A  IG+ S  A S L
Sbjct: 391 FGGK--------RPFGVSILYMGWDKHYGFQLYQSDPSGNYGGWKATCIGNNSANAVSLL 546

Query: 182 QEVYHKS-MTLKEAIKSSLIILKQVME-EKLNATNIELATV 220
           ++ Y +   +L EA+  S+ +L + ++  KL    +E+AT+
Sbjct: 547 KQEYKEDESSLDEALALSIKVLGKTLDLTKLTPDKVEMATL 669
>14551
          Length = 1344

 Score =  127 bits (318), Expect = 5e-30,   Method: Compositional matrix adjust.
 Identities = 72/237 (30%), Positives = 124/237 (52%), Gaps = 2/237 (0%)
 Frame = +3

Query: 7   EYDRGVNTFSPEGRLFQVEYAIEAIKLGSTAIGIQTSEGVCLAVEKRITSPLMEPSSIEK 66
            Y   + TFSP G+L Q+EYA+ A+  G+ ++GI+ + GV LA EK+  S   +  SI K
Sbjct: 150 RYSFSLTTFSPSGKLVQIEYALAAVGAGAPSVGIKATNGVVLATEKKQKSVXYDEHSINK 329

Query: 67  IVEIDAHIGCAMSGLIADAKTLIDKARVETQNHWFTYNETMTVESVTQAVSNLALQFGEE 126
           +  I  +IG   SG+  D + L  +AR   + +   YNE +    + Q V+ +  +F + 
Sbjct: 330 VETITKNIGIVYSGMGPDYRVLCRRARKLAEQYKRVYNEQIPTAQLVQRVAAVMQEFTQS 509

Query: 127 DADPGAMSRPFGVALLFGGVDE--KGPQLFHMDPSGTFVQCDARAIGSASEGAQSSLQEV 184
                   RPFGV+LL  G DE  K P L+  DPSG +    A A+G      ++ L++ 
Sbjct: 510 GG-----VRPFGVSLLMAGWDEDDKKPFLYQCDPSGAYFAWKATAMGKNHINGKTFLEKR 674

Query: 185 YHKSMTLKEAIKSSLIILKQVMEEKLNATNIELATVQPGQNFHMFTKEELEEVIKDI 241
           Y +++ L++A+ ++++ LK+  E ++   NIE+        F      E+++ +  +
Sbjct: 675 YSETLELEDAVHTAILALKESFEGQMTEDNIEIGICN-SSGFRRLEPSEIKDYLASV 842
>04255
          Length = 1758

 Score = 90.5 bits (223), Expect = 5e-19,   Method: Compositional matrix adjust.
 Identities = 51/202 (25%), Positives = 100/202 (49%), Gaps = 4/202 (1%)
 Frame = -2

Query: 38   IGIQTSEGVCLAVEKRITSPLMEPSSIEKIVEIDAHIGCAMSGLIADAKTLIDKARVETQ 97
             G Q     C    +++   L++P+++  +  +   IGC M+G+IAD+++ + +AR E  
Sbjct: 1514 CGCQRKRQRCYCHTEKVPDKLLDPTTVTHLYSLTERIGCVMTGMIADSQSQVQRARYEAA 1335

Query: 98   NHWFTYNETMTVESVTQAVSNLALQFGEEDADPGAMSRPFGVAL-LFGGVDEKGPQLFHM 156
               +TY   + V+ + + ++N+   + +      A  RP G  + L G  DEKGP+++  
Sbjct: 1334 KWKYTYGYDIPVDMLCKRIANINQVYTQ-----SAEMRPLGCCMILIGYDDEKGPEVYKT 1170

Query: 157  DPSGTFVQCDARAIGSASEGAQSSLQEVYHK--SMTLKEAIKSSLIILKQVMEEKLNATN 214
            DP+G +    A + GS    A   L++   K    T  EA + ++  L  V+     A+ 
Sbjct: 1169 DPAGYYCGFKATSAGSKQLEANGFLEKKIKKKQDFTYNEAAEIAITCLSTVLSADFKASE 990

Query: 215  IELATV-QPGQNFHMFTKEELE 235
            +E+  V +   NF + T+ +++
Sbjct: 989  VEVGIVTKDNPNFRILTEADID 924

 Score = 37.4 bits (85), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 16/44 (36%), Positives = 27/44 (61%), Gaps = 1/44 (2%)
 Frame = -3

Query: 14   TFSPEGRLFQVEYAIEAIKLGS-TAIGIQTSEGVCLAVEKRITS 56
              SPEGRL+QVEYA +AI  G  T++ ++  +   +  +K+  +
Sbjct: 1588 NLSPEGRLYQVEYAFKAINQGGLTSVAVRGKDSAVIVTQKKFRT 1457
>19133
          Length = 692

 Score = 69.7 bits (169), Expect = 1e-12,   Method: Compositional matrix adjust.
 Identities = 45/162 (27%), Positives = 72/162 (44%), Gaps = 4/162 (2%)
 Frame = +1

Query: 81  LIADAKTLIDKARVETQNHWFTYNETMTVESVTQAVSNLALQFGEEDADPGAMSRPFGVA 140
           L ADA+ L +  + E  +  + Y + + V  +  A+ N  LQ            RPFGV 
Sbjct: 1   LTADARLLCNFMQTECLDSRWAYQQPLPVSRLVSAIGN-KLQIPTHRYG----RRPFGVG 165

Query: 141 LLFGGVDEKGPQLFHMDPSGTFVQCDARAIGSASEGAQSSLQEVYHK--SMTLKEAIKSS 198
           LL  G D  GP ++   PS  +  C A AIG+ S+ A++ L+    +    +L E +K  
Sbjct: 166 LLIAGYDWSGPHIYQTCPSANYYDCKAMAIGARSQSARTYLERHLDQFPQCSLDELVKHG 345

Query: 199 LIILKQVM--EEKLNATNIELATVQPGQNFHMFTKEELEEVI 238
           L  L+  +  E  L+  N  L  V     F ++  E +   +
Sbjct: 346 LRALRDTLPSEVTLSTKNCSLGIVDKDMKFKIYDDENVASYL 471
>03425
          Length = 933

 Score = 42.4 bits (98), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 25/86 (29%), Positives = 45/86 (52%), Gaps = 3/86 (3%)
 Frame = +3

Query: 138 GVALLFGGVDEKGPQLFHMDPSGTFVQCDARAIGSASEGAQSSLQEVYHKSMTLKEAIKS 197
           G AL+ GGVD  GP L+ + P G+  +     +GS S  A ++ ++ +   M+  EA+K 
Sbjct: 6   GAALVLGGVDVTGPHLYSIWPHGSTDKLPFVTMGSGSLAAMATFEDRFKPDMSRDEAMK- 182

Query: 198 SLI---ILKQVMEEKLNATNIELATV 220
            L+   I   +  +  + +NI+L  +
Sbjct: 183 -LVRDAIAAGIFNDLGSGSNIDLCVI 257
>28971
          Length = 437

 Score = 42.0 bits (97), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 18/37 (48%), Positives = 23/37 (62%)
 Frame = +1

Query: 135 RPFGVALLFGGVDEKGPQLFHMDPSGTFVQCDARAIG 171
           RPFGV+LL  G D + P L+  DPSG +    A A+G
Sbjct: 31  RPFGVSLLICGWDNERPYLYQSDPSGAYFAWKATAMG 141
>01337
          Length = 2947

 Score = 38.9 bits (89), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 22/68 (32%), Positives = 29/68 (42%)
 Frame = -3

Query: 128  ADPGAMSRPFGVALLFGGVDEKGPQLFHMDPSGTFVQCDARAIGSASEGAQSSLQEVYHK 187
            AD     RP  V +L  G+D+ GP LF +D  G  +Q      G       S +   Y K
Sbjct: 1097 ADALRSQRPKFVNILMAGMDDSGPALFFLDYLGALIQVPFAVHGYGGMFTLSIMDRYYKK 918

Query: 188  SMTLKEAI 195
             M   EA+
Sbjct: 917  DMNKDEAV 894
>37174
          Length = 146

 Score = 35.8 bits (81), Expect = 0.015,   Method: Composition-based stats.
 Identities = 16/43 (37%), Positives = 25/43 (58%)
 Frame = +1

Query: 7  EYDRGVNTFSPEGRLFQVEYAIEAIKLGSTAIGIQTSEGVCLA 49
          +Y R  N   P  +L Q+EYA+ A+  G+  +GI+ + GV L 
Sbjct: 13 QYKRVYNEQIPTAQLVQIEYALAAVGAGAPVVGIKATNGVVLG 141
>11023
          Length = 1057

 Score = 33.5 bits (75), Expect = 0.077,   Method: Compositional matrix adjust.
 Identities = 17/50 (34%), Positives = 27/50 (54%)
 Frame = -2

Query: 141 LLFGGVDEKGPQLFHMDPSGTFVQCDARAIGSASEGAQSSLQEVYHKSMT 190
           +L G  DEKGP+++  DP+G +    A + GS    A   L++   +S T
Sbjct: 993 ILIGYDDEKGPEVYKTDPAGYYCGFKATSAGSKQLEANGFLEKRSRRSKT 844
>00434
          Length = 892

 Score = 29.3 bits (64), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 13/16 (81%), Positives = 14/16 (87%)
 Frame = +1

Query: 226 FHMFTKEELEEVIKDI 241
           F MF+KEELE VIKDI
Sbjct: 10  FQMFSKEELEAVIKDI 57
>00497
          Length = 1184

 Score = 26.9 bits (58), Expect = 7.5,   Method: Compositional matrix adjust.
 Identities = 31/114 (27%), Positives = 50/114 (43%), Gaps = 3/114 (2%)
 Frame = +3

Query: 94  VETQNHWFTY--NETMTVESVTQAVSNLALQFGEEDADPGAMSRPFGVALLFGGVDEKGP 151
           VET+   F+Y  N+ M   SV   +S + L +            P+    +  G+D +G 
Sbjct: 24  VETRLKMFSYIHNKEMDTSSVAAMLSTI-LYYRR--------FFPYYXYNIVAGLDTEGK 176

Query: 152 Q-LFHMDPSGTFVQCDARAIGSASEGAQSSLQEVYHKSMTLKEAIKSSLIILKQ 204
             +F  DP G++ +   RA GSAS    S LQ +    + +K    +  + L Q
Sbjct: 177 GCVFSFDPVGSYERETYRAGGSAS----SMLQPLLDNQIGMKNQAGAKQVPLSQ 326
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31559887|ref|NP_758512.2| methylenetetrahydrofolate
dehydrogenase (NADP+ dependent) 1-like [Mus musculus]
         (977 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

11972                                                                 352   3e-97
06310                                                                 199   4e-51
05632                                                                  87   4e-17
>11972
          Length = 736

 Score =  352 bits (904), Expect = 3e-97,   Method: Compositional matrix adjust.
 Identities = 169/241 (70%), Positives = 196/241 (81%)
 Frame = -3

Query: 594 EKGYSRQAQFDIAVASEIMAVLALTDSLTDMKERLGRMVVASDKDGQPVTAEDLGVTGAL 653
           EK  +R+ QFDI VASEIMA+LALT  L DM+ERLG+MVVAS K G+PVTA+DLGV+GAL
Sbjct: 728 EKNMTRETQFDITVASEIMAILALTSDLRDMRERLGKMVVASSKAGEPVTADDLGVSGAL 549

Query: 654 TVLMKDAIKPNLMQTLEGTPVFVHAGPFANIAHGNSSVLADKIALKLVGEEGFVVTEAGF 713
           TVLM+DA++PNLMQTLEGTPVFVHAGPFANIAHGNSS+LADK+ALK+VGE+GFVVTEAGF
Sbjct: 548 TVLMRDALRPNLMQTLEGTPVFVHAGPFANIAHGNSSILADKLALKIVGEKGFVVTEAGF 369

Query: 714 GADIGMEKFFNIKCRXXXXXXXXXXXXXXXXXXKMHGGGPSVTAGVPLKKEYTEENIQLV 773
           GADIGMEKFFNIKCR                  KMHGGGP+VTAGVPL K+YTEEN++LV
Sbjct: 368 GADIGMEKFFNIKCRYSGLVPNAVVLVATVRALKMHGGGPTVTAGVPLPKDYTEENLELV 189

Query: 774 ADGCCNLQKQIQIAQLFGVPVVVALNVFKTDTRAEIDLVCELAKRAGAFDAVPCYHWSAG 833
             GC NL KQI+ A  FG+PVVVA+N F TDT+AE++LV  LA+  GAFDAV   HW+ G
Sbjct: 188 EKGCSNLLKQIENANYFGIPVVVAVNAFATDTQAELELVQRLARENGAFDAVISSHWANG 9

Query: 834 G 834
           G
Sbjct: 8   G 6
>06310
          Length = 1575

 Score =  199 bits (506), Expect = 4e-51,   Method: Compositional matrix adjust.
 Identities = 89/125 (71%), Positives = 108/125 (86%)
 Frame = +2

Query: 852 SRFQFLYDVQLPIVEKIRVIAQTVYGAKDIELSPEAQSKIDRYTQQGFGNLPICMAKTHL 911
           S FQFLYDV+LPI EKI +IA+ +YGA  +EL P A+ +++RYT+QGF +LPICMAKTHL
Sbjct: 11  SNFQFLYDVKLPIEEKIAIIAKKIYGADGVELEPLAKEQVERYTRQGFNDLPICMAKTHL 190

Query: 912 SLSHEPDKKGVPRDFTLPISDVRASIGAGFIYPLVGTMSTMPGLPTRPCFYDIDLDTETE 971
           SLSH P+KKG P+ F LPI +VRASIGAGFIYPL+GTMSTMPGLPTRPCFYDID+D +TE
Sbjct: 191 SLSHMPEKKGAPKGFVLPIREVRASIGAGFIYPLIGTMSTMPGLPTRPCFYDIDIDPDTE 370

Query: 972 QVKGL 976
           ++ GL
Sbjct: 371 EIVGL 385
>05632
          Length = 930

 Score = 86.7 bits (213), Expect = 4e-17,   Method: Composition-based stats.
 Identities = 37/45 (82%), Positives = 43/45 (95%)
 Frame = -1

Query: 932 DVRASIGAGFIYPLVGTMSTMPGLPTRPCFYDIDLDTETEQVKGL 976
           +VRASIGAGFIYPL+GTMSTMPGLPTRPCFYDID+D +TE++ GL
Sbjct: 930 EVRASIGAGFIYPLIGTMSTMPGLPTRPCFYDIDIDPDTEEIVGL 796
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31980873|ref|NP_080940.2| vacuolar protein sorting 53
[Mus musculus]
         (832 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

07356                                                                 352   5e-97
20681                                                                  32   0.83 
04107                                                                  30   3.8  
16285                                                                  30   4.2  
>07356
          Length = 860

 Score =  352 bits (902), Expect = 5e-97,   Method: Compositional matrix adjust.
 Identities = 174/266 (65%), Positives = 212/266 (79%), Gaps = 7/266 (2%)
 Frame = +1

Query: 561 YCLATTQQLEEKLKEKVDVSLTERINLTGEMDTFSTVISSSIQLLVQDLDAACDPALIAM 620
           YC+ TT QL +KL+EKVD  L   I+L+ E D F TVISS IQLLVQDL+AAC+PAL AM
Sbjct: 1   YCMETTSQLADKLREKVDPELRSSIDLSAEQDMFHTVISSCIQLLVQDLEAACEPALTAM 180

Query: 621 SKMPWQNVEHVGDQSPYVTSVILHIKQNVPIIRDNLASTRKYFTQFCIKFANSFIPKFIT 680
           SKMPW  +E VGDQS YVT++  H+KQN+P+IRDNL S+RKYFTQFC+KFANSFIPKFI 
Sbjct: 181 SKMPWSTIEAVGDQSGYVTAITAHLKQNLPVIRDNLLSSRKYFTQFCVKFANSFIPKFIH 360

Query: 681 HLFKCKPISMVGAEQLLLDTHSLKMVLLDLPSIGSQVVRKAPASYTKIVVKGMTRAEMIL 740
            LFKCKP S V AEQLLLDTHSLK VLL+LPS+GSQV RKAPAS+TKIVVKGMT+AEMIL
Sbjct: 361 TLFKCKPGSTVAAEQLLLDTHSLKTVLLELPSLGSQVARKAPASFTKIVVKGMTKAEMIL 540

Query: 741 KVVMAPHEPLVVFVDNYIKLLTDCNSETFQKILDMKGLKRSEQSSMLELLRQRLP--APP 798
           KVVM+PH+P   FVDN+I+LLTD +   FQ++L+MKG++R+EQ +++E+ R R+P  A  
Sbjct: 541 KVVMSPHDPPQGFVDNFIRLLTDADVTEFQRVLEMKGVRRAEQGTLIEMYRARVPVSAVI 720

Query: 799 SGTEGSS-----TLSLIAPTPEQESS 819
              +G S     TLS +A +PE ESS
Sbjct: 721 GNAQGQSLPLSPTLSQVA-SPEPESS 795
>20681
          Length = 1217

 Score = 32.3 bits (72), Expect = 0.83,   Method: Compositional matrix adjust.
 Identities = 36/134 (26%), Positives = 61/134 (45%), Gaps = 14/134 (10%)
 Frame = -3

Query: 55  EQSLANIDDVVNKIR--LKIRRLDDNIRTV--VRGQTNVGQDGRQALEEAQKAIQQLFGK 110
           EQ LA+  ++VNK++  L   R+    RT   +   +N+ ++  + LE A +  Q L  K
Sbjct: 555 EQLLADSKNLVNKLQPLLCAERVSQMTRTYNDIDAVSNLLEEKERDLELAARIGQTLLSK 376

Query: 111 IKDIKDKAEKSEQMVKEITRDIKQLDHAKRHLTTSI----------TTLNHLHMLAGGVD 160
            KD+  + E  E+ +   T  IKQL H        +          T  ++L  + GG  
Sbjct: 375 NKDLVGRKEALEEQLSLATDTIKQLKHELSKKVQQLEVYDQDLQYQTCKDNLASVGGGDA 196

Query: 161 SLEAMTRRRQYGEV 174
           SL+    ++Q G +
Sbjct: 195 SLKVEKLQKQVGSL 154
>04107
          Length = 2502

 Score = 30.0 bits (66), Expect = 3.8,   Method: Compositional matrix adjust.
 Identities = 24/86 (27%), Positives = 38/86 (44%), Gaps = 19/86 (22%)
 Frame = +1

Query: 132 IKQLDHAKR-HLTTSITTLNHLHML--------------AGGVDSLEAMTRRRQYGE--- 173
           + +LDH  R HL    T LNH+HM                G + +L+ + RR + G    
Sbjct: 502 VNRLDHDLREHLRPVTTRLNHVHMRMSIHFPELRLIQYDCGKLQTLDVLLRRLKTGSHRV 681

Query: 174 -VANLLQGVMNVLEHFHKYMGIPQIR 198
            +   +  +++VLE F  Y G   +R
Sbjct: 682 LIFTQMTKMLDVLEAFLNYHGHRYLR 759
>16285
          Length = 819

 Score = 30.0 bits (66), Expect = 4.2,   Method: Composition-based stats.
 Identities = 21/59 (35%), Positives = 26/59 (44%), Gaps = 8/59 (13%)
 Frame = +3

Query: 640 SVILHIKQNVPIIRD--------NLASTRKYFTQFCIKFANSFIPKFITHLFKCKPISM 690
           S ILH KQNV + R         NLA  +     FCI F NS +P      F  K + +
Sbjct: 645 SDILHFKQNVHMFRQDFTLKEFHNLAKVQIMTINFCIHF-NSNVPLMFRQDFTLKDVML 818
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|126723336|ref|NP_031557.2| B-cell receptor-associated
protein 37 [Mus musculus]
         (299 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

07529                                                                 349   7e-97
20881                                                                 199   1e-56
30974                                                                  31   0.70 
05679                                                                  30   1.5  
>07529
          Length = 1399

 Score =  349 bits (896), Expect = 7e-97,   Method: Compositional matrix adjust.
 Identities = 169/243 (69%), Positives = 202/243 (83%)
 Frame = +2

Query: 57  GVQQDTILAEGLHFRIPWFQYPIIYDIRARPRKISSPTGSKDLQMVNISLRVLSRPNAQE 116
           GVQ+D +  EGLHFR+PWFQYPIIYDIR+RPRKI+SPTGSKDLQMVNISLRVLSRP A +
Sbjct: 5   GVQED-VYVEGLHFRVPWFQYPIIYDIRSRPRKITSPTGSKDLQMVNISLRVLSRPIASQ 181

Query: 117 LPSMYQRLGLDYEERVLPSIVNEVLKSVVAKFNASQLITQRAQVSLLIRRELTERAKDFS 176
           LP +Y+ LG DY+ERVLPSI NEVLKSVVAKFNASQLITQR QVSLLIRRELTERAKDF+
Sbjct: 182 LPHVYRSLGTDYDERVLPSICNEVLKSVVAKFNASQLITQRQQVSLLIRRELTERAKDFN 361

Query: 177 LILDDVAITELSFSREYTXXXXXXXXXXXXXXXXXFLVEKAKQEQRQKIVQAEGEAEAAK 236
           +ILDDV+ITELSF REYT                 FLVEKAKQE++QK+VQA+GEA+AAK
Sbjct: 362 IILDDVSITELSFGREYTAAVESKQVAQQEAQRAQFLVEKAKQEKQQKMVQADGEAQAAK 541

Query: 237 MLGEALSKNPGYIKLRKIRAAQNISKTIATSQNRIYLTADNLVLNLQDESFTRGSDSLIK 296
           ++G+A+  NPG++KLRKIRAAQNIS+T+A SQNR+YL A  L+LN+ ++ F   +D++ K
Sbjct: 542 LIGQAVQANPGFLKLRKIRAAQNISRTVAQSQNRVYLNASALLLNIGEKEFDEAADAVSK 721

Query: 297 GKK 299
            KK
Sbjct: 722 RKK 730
>20881
          Length = 2017

 Score =  199 bits (505), Expect(2) = 1e-56,   Method: Compositional matrix adjust.
 Identities = 97/203 (47%), Positives = 140/203 (68%), Gaps = 1/203 (0%)
 Frame = +1

Query: 72  IPWFQYPIIYDIRARPRKISSPTGSKDLQMVNISLRVLSRPNAQELPSMYQRLGLDYEER 131
           IPW Q PII+D R+RPR +   TGSKDLQ VNI+LR+L RP    LP ++  LG DY+ER
Sbjct: 208 IPWVQKPIIFDCRSRPRNVPVVTGSKDLQNVNITLRILFRPQVPSLPKIFTNLGTDYDER 387

Query: 132 VLPSIVNEVLKSVVAKFNASQLITQRAQVSLLIRRELTERAKDFSLILDDVAITELSFSR 191
           VLPSI NEVLK++VA+F+AS+LITQR  VS  +  ELT+RA  F L+LDD+++T L+F R
Sbjct: 388 VLPSITNEVLKAIVAQFDASELITQRELVSQKVSEELTDRALQFGLLLDDISLTHLTFGR 567

Query: 192 EYTXXXXXXXXXXXXXXXXXFLVEKAKQEQRQKIVQAEGEAEAAKMLGEALSK-NPGYIK 250
           E+T                 F+VEKA+Q+++  ++ AEG++ AA+ L +A  +   G ++
Sbjct: 568 EFTEAVESKQVAQQEAERARFVVEKAEQQKKAAVISAEGDSLAAEQLAKAFGEAGEGLVE 747

Query: 251 LRKIRAAQNISKTIATSQNRIYL 273
           LRK+ AA++I+  ++ S+N +YL
Sbjct: 748 LRKLEAAEDIAYQLSRSRNVVYL 816

 Score = 38.5 bits (88), Expect(2) = 1e-56,   Method: Compositional matrix adjust.
 Identities = 17/38 (44%), Positives = 25/38 (65%)
 Frame = +2

Query: 38  ESVFTVEGGHRAIFFNRIGGVQQDTILAEGLHFRIPWF 75
            +++ V+GGHRA+ F+R  GV QD +  EG H  +P F
Sbjct: 107 SALYNVDGGHRAVIFDRFRGV-QDAVSGEGTH--VPRF 211
>30974
          Length = 823

 Score = 30.8 bits (68), Expect = 0.70,   Method: Compositional matrix adjust.
 Identities = 12/32 (37%), Positives = 19/32 (59%)
 Frame = -2

Query: 68  LHFRIPWFQYPIIYDIRARPRKISSPTGSKDL 99
           L  R+ W +  ++Y +R + R+ISS T  K L
Sbjct: 126 LWMRVDWSELMLLYQLRMKSRQISSSTSCKAL 31
>05679
          Length = 876

 Score = 29.6 bits (65), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 12/24 (50%), Positives = 19/24 (79%)
 Frame = -2

Query: 260 ISKTIATSQNRIYLTADNLVLNLQ 283
           + K +ATSQN+IY+  + LV+NL+
Sbjct: 713 LDKKLATSQNKIYVNLEYLVMNLK 642
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|189339262|ref|NP_079770.2| ATPase, H+ transporting,
lysosomal V1 subunit C1 [Mus musculus]
         (382 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

22396                                                                 324   7e-97
34639                                                                  32   0.33 
>22396
          Length = 916

 Score =  324 bits (830), Expect(3) = 7e-97,   Method: Compositional matrix adjust.
 Identities = 154/237 (64%), Positives = 189/237 (79%), Gaps = 3/237 (1%)
 Frame = +3

Query: 147 KGNLQNLERKNAGSLLTRSLAEIVKKDDFVLDSEYLVTLLVVVPKLNHNDWIKQYETLAE 206
           KGNLQNLE+K  GSLLTR+LA++VKK+ F+LDSEYL TLLV+VPK N NDW+  YE + +
Sbjct: 126 KGNLQNLEKKKTGSLLTRNLADLVKKEHFILDSEYLTTLLVIVPKANANDWLANYEKITD 305

Query: 207 MVVPRSSNVLSEDQDSYLCNVTLFRKAVDDFRHKARENKFIVRDFQYNEEEMKADKEEMT 266
           M+VPRS+ ++ ED D  L NVTLF+K  ++F+  ARE KFIVRDF YNEEE+ A K EMT
Sbjct: 306 MIVPRSTQLIKEDHDYCLFNVTLFKKVTEEFKLHARERKFIVRDFVYNEEELAAGKNEMT 485

Query: 267 RLSTDKKKQFGPLVRWLKVNFSEAFIAWIHIKALRVFVESVLRYGLPVNFQAMLLQPNKK 326
           +L TDKKKQFGPLVRWLKVNFSEAF A IH+KALRVFVESVLRYGLPVNFQA+L++PNKK
Sbjct: 486 KLMTDKKKQFGPLVRWLKVNFSEAFCALIHVKALRVFVESVLRYGLPVNFQAILIEPNKK 665

Query: 327 SVKKLREVLHELYKHLXXXXXXXXXXP---MDIPGLNLSQQEYYPYVYYKIDCNLLE 380
           SVK+LR+VL++LY HL              +DIPGL   Q EYYPYV+YK++ +++E
Sbjct: 666 SVKRLRDVLNQLYGHLDGASAGGNVSSADNVDIPGLGFGQSEYYPYVFYKVNIDMVE 836

 Score = 41.2 bits (95), Expect(3) = 7e-97,   Method: Compositional matrix adjust.
 Identities = 17/20 (85%), Positives = 20/20 (100%)
 Frame = +2

Query: 106 QWDMAKYPIKQSLKNISEII 125
           QWDMAKYPIKQSL+NI++II
Sbjct: 2   QWDMAKYPIKQSLRNIADII 61

 Score = 28.5 bits (62), Expect(3) = 7e-97,   Method: Compositional matrix adjust.
 Identities = 11/20 (55%), Positives = 16/20 (80%)
 Frame = +1

Query: 126 AKGVTQIDNDLKSRASAYNN 145
           +K + QID DLK+++ AYNN
Sbjct: 61  SKQIGQIDGDLKTKSQAYNN 120
>34639
          Length = 763

 Score = 32.3 bits (72), Expect = 0.33,   Method: Compositional matrix adjust.
 Identities = 21/80 (26%), Positives = 41/80 (51%), Gaps = 2/80 (2%)
 Frame = +3

Query: 105 FQWDMAKYPIKQSLKNISEIIAKGVTQIDNDLKSRASAYNNLKGNLQNLERKNAGSL--L 162
           + WD + +  + SL NISEI A    ++ +   S   +Y++   ++  L    A ++  +
Sbjct: 249 YHWDTSDWAPRPSLPNISEIPAN---EVADSPASTPPSYDS-NEHVPMLASTTASAIDSM 416

Query: 163 TRSLAEIVKKDDFVLDSEYL 182
           T  ++ I    D++ DSEY+
Sbjct: 417 THDISTIPDH-DYMTDSEYV 473
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|9789873|ref|NP_062622.1| methionine aminopeptidase 2
[Mus musculus]
         (478 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

25432                                                                 345   2e-95
28444                                                                 132   4e-31
05442                                                                  90   2e-18
18700                                                                  35   0.075
>25432
          Length = 557

 Score =  345 bits (885), Expect = 2e-95,   Method: Compositional matrix adjust.
 Identities = 160/184 (86%), Positives = 173/184 (94%)
 Frame = -3

Query: 261 IDCAFTVTFNPKYDILLTAVKDATNTGIKCAGIDVRLCDVGEAIQEVMESYEVEIDGKTY 320
           IDCAFT+ FNPKYD LL AVKDATNTGI+ AGIDVRLCDVGE IQEVMESYEVE+DGKTY
Sbjct: 552 IDCAFTLAFNPKYDQLLAAVKDATNTGIREAGIDVRLCDVGERIQEVMESYEVELDGKTY 373

Query: 321 QVKPIRNLNGHSIGPYRIHAGKTVPIVKGGEATRMEEGEVYAIETFGSTGKGVVHDDMEC 380
           QVKPIRNLNGHS+G YRIHAGKTVPIVKGG+ATRMEEGEVYAIETFGSTGKGVVHDDME 
Sbjct: 372 QVKPIRNLNGHSVGQYRIHAGKTVPIVKGGDATRMEEGEVYAIETFGSTGKGVVHDDMET 193

Query: 381 SHYMKNFDVGHVPIRLPRTKHLLNVINENFGTLAFCRRWLDRLGESKYLMALKNLCDLGI 440
           SHYMKNF+VGHVP+RL ++K LLNVIN NF TLAFCRRWLDRLG++KYLMALKNLCD+GI
Sbjct: 192 SHYMKNFEVGHVPLRLAKSKQLLNVINNNFSTLAFCRRWLDRLGQTKYLMALKNLCDVGI 13

Query: 441 VDPY 444
           +DPY
Sbjct: 12  IDPY 1
>28444
          Length = 623

 Score =  132 bits (331), Expect = 4e-31,   Method: Compositional matrix adjust.
 Identities = 57/98 (58%), Positives = 78/98 (79%)
 Frame = +1

Query: 110 KVQTDPPSVPICDLYPNGVFPKGQECEYPPTQDGRTAAWRTTSEEKKALDQASEEIWNDF 169
           K QTDPP++P+C+L+P+G FP+G+ C+YP  QD +TA  R T EEK+ALD+A   ++ + 
Sbjct: 328 KTQTDPPTIPVCELFPDGNFPEGEICKYPVDQDNQTAKDRFTDEEKRALDRAQTYLYQEM 507

Query: 170 REAAEAHRQVRKYVMSWIKPGMTMIEICEKLEDCSRKL 207
           R+A+EAHRQ RKY+ S+IKPGMTMI+ICE LE  SRK+
Sbjct: 508 RQASEAHRQTRKYMQSYIKPGMTMIDICETLESTSRKM 621
>05442
          Length = 1171

 Score = 89.7 bits (221), Expect = 2e-18,   Method: Compositional matrix adjust.
 Identities = 79/277 (28%), Positives = 120/277 (43%), Gaps = 17/277 (6%)
 Frame = +1

Query: 207 LIKENGLNAGLAFPTGCSLNNCAAHYTPNAGDTTV-LQYDDICKIDFGTHISGRIIDCAF 265
           L K  G   G+AFPT  S+NNC  H++P   D  + L+  D+ KID G H+ G I   A 
Sbjct: 100 LQKGQGNEKGIAFPTCVSINNCICHFSPLKSDPDITLKDGDMVKIDLGAHVDGYIGVAAH 279

Query: 266 TVTFNPKYDI--------LLTAVKDATNTGIKCAGIDVRLCDVGEAIQEVMESYEVEIDG 317
           T+      D         ++TA   A    ++          V + IQ+V E+       
Sbjct: 280 TLVVGASKDKKVSGRKADVMTAAHMAVEAALRMVKPGNENDQVTDCIQKVAEA------- 438

Query: 318 KTYQVKPIRNLNGHSIGPYRIHAGKTVPIVKGGEATR-------MEEGEVYAIETFGSTG 370
             Y  KP+  +  H +    I   K   I    EA R        E  EVYAI+   STG
Sbjct: 439 --YNCKPVEGMLSHQLLKDVIDGDKAF-IQNPSEAQRKDHDKCEFEVHEVYAIDVIISTG 609

Query: 371 KGVVHD-DMECSHYMKNFDVGHVPIRLPRTKHLLNVINENFGTLAFCRRWLDRLGESKYL 429
           +G   + D   + Y K   V    +++  ++  L+  ++ FG + F  R L+   E K  
Sbjct: 610 EGKGRELDTRTTVYKKRDMV--YQLKMKASRQFLSETDKKFGLMPFSLRLLE--DEKKAK 777

Query: 430 MALKNLCDLGIVDPYPPLCDIKGSYTAQFEHTILLRP 466
           M +      G++ P+  L D +G   AQF+ T++L P
Sbjct: 778 MGVVECVKHGLMQPFGVLFDREGEVVAQFKTTVILMP 888
>18700
          Length = 1224

 Score = 35.0 bits (79), Expect = 0.075,   Method: Compositional matrix adjust.
 Identities = 19/54 (35%), Positives = 23/54 (42%)
 Frame = +1

Query: 415 FCRRWLDRLGESKYLMALKNLCDLGIVDPYPPLCDIKGSYTAQFEHTILLRPTC 468
           +C  W   +G   Y +A       G  DPYPPLC +  S      H IL  P C
Sbjct: 298 YCGAWCTGMGSDSYTLAACTXWS-GEGDPYPPLCSLPPSGHVYCHHRILKTPRC 456
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6754910|ref|NP_035078.1| nuclear distribution gene C
homolog [Mus musculus]
         (332 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

08585                                                                 344   3e-95
02763                                                                 110   6e-25
22648                                                                  69   2e-12
14697                                                                  45   3e-05
09499                                                                  42   3e-04
23848                                                                  28   4.6  
>08585
          Length = 2828

 Score =  344 bits (883), Expect = 3e-95,   Method: Compositional matrix adjust.
 Identities = 177/345 (51%), Positives = 222/345 (64%), Gaps = 13/345 (3%)
 Frame = -2

Query: 1    MGGEQEEERFDGMLLAMAQQHEGGVQELVNTFFSFLRRKTDFFIGGEEGMAEKLITQTFN 60
            M    + ERFDGML+ MAQQ EGG+ EL+ TFF FL+RKTDFF G     AE+L+  TF 
Sbjct: 1855 MSNNADPERFDGMLMTMAQQCEGGIHELLGTFFGFLQRKTDFFTGTGSAQAEELVMSTFR 1676

Query: 61   HHNQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----XXXXPGPQIKELTDEEAERLQ 116
             H                                           P+IKELTD EAE L+
Sbjct: 1675 KHQATAQKLKKEQMEKEKKKAEKKAKEREEAERKRKEAEQKTEEEPKIKELTDAEAEALE 1496

Query: 117  LEIDQKK---------DAEDQEAQLKNGSLDSPGXXXXXXXXXXXXXXXXXXXXPNLGNG 167
             E+ QKK         DAE Q+ + K  + D                       PN GNG
Sbjct: 1495 KELSQKKQEPEISANGDAEPQKKEEKTKAADD--------XDEEEDEKDKGKIKPNDGNG 1340

Query: 168  ADLPNYRWTQTLAELDLAVPFRVSFRLKGKDVVVDIQRRHLRVGLKGQPPVVDGELYNEV 227
            ADLP Y+WTQTL E+++ +PF V+F LKGKD+VVDI ++H++ GLKG PP++DG++YN V
Sbjct: 1339 ADLPTYKWTQTLGEIEIRIPFNVNFPLKGKDLVVDIGKKHIKAGLKGHPPILDGDMYNSV 1160

Query: 228  KVEESSWLIEDGKVVTVHLEKINKMEWWNRLVTSDPEINTKKINPENSKLSDLDSETRSM 287
            K+EES+W IED K++ ++LEK+N+MEWW+R+VT+DPEINTKK+ PENSKLSDLD ETRSM
Sbjct: 1159 KIEESTWCIEDKKLLLINLEKVNQMEWWSRIVTTDPEINTKKVQPENSKLSDLDGETRSM 980

Query: 288  VEKMMYDQRQKSMGLPTSDEQKKQEILKKFMDQHPEMDFSKAKFN 332
            VEKMMYDQRQK  GLPTSDEQKK++++KKFM QHPEMDFSK KF+
Sbjct: 979  VEKMMYDQRQKERGLPTSDEQKKEDVMKKFMSQHPEMDFSKCKFS 845
>02763
          Length = 2590

 Score =  110 bits (276), Expect = 6e-25,   Method: Compositional matrix adjust.
 Identities = 64/162 (39%), Positives = 102/162 (62%), Gaps = 4/162 (2%)
 Frame = +3

Query: 162 PNLGNGADLPNYRWTQTLAELDLAVPFRVSFRLKGKDVVVDIQRRHLRVGLKGQPPV--- 218
           P   NGA   NY W+Q++ ++D+ V    +  LKGK V VDI ++ L V  KG   V   
Sbjct: 555 PESYNGAVRDNYSWSQSITDVDVRVKVPKTV-LKGKAVQVDIAKKRLCVRYKGSDGVWEE 731

Query: 219 -VDGELYNEVKVEESSWLIEDGKVVTVHLEKINKMEWWNRLVTSDPEINTKKINPENSKL 277
            V G+L  E++ +ES W +  G+ V ++LEK  +  WW+ +   +P+INT+KI+  +  +
Sbjct: 732 GVTGDLTWEIRPDESMWTLSPGQHVYINLEK-KEERWWDGVFVDEPKINTRKIDC-SRPI 905

Query: 278 SDLDSETRSMVEKMMYDQRQKSMGLPTSDEQKKQEILKKFMD 319
           +DLD E ++ +E+MM+++RQK MGLP S EQKK ++L++  D
Sbjct: 906 TDLDDEAQAKIEEMMFNERQKRMGLPQSHEQKKMDMLRQAWD 1031
>22648
          Length = 314

 Score = 69.3 bits (168), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 29/44 (65%), Positives = 37/44 (84%)
 Frame = +2

Query: 162 PNLGNGADLPNYRWTQTLAELDLAVPFRVSFRLKGKDVVVDIQR 205
           PN GNGADLP Y+WTQTL E+++ +PF V+F LKGKD+VVDI +
Sbjct: 182 PNDGNGADLPTYKWTQTLGEIEIRIPFNVNFPLKGKDLVVDIGK 313
>14697
          Length = 553

 Score = 45.4 bits (106), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 45/156 (28%), Positives = 70/156 (44%)
 Frame = +3

Query: 177 QTLAELDLAVPFRVSFRLKGKDVVVDIQRRHLRVGLKGQPPVVDGELYNEVKVEESSWLI 236
           QTL E+++ V       + GK V  DI+ R L+V + G+  ++DGEL   V  ++S+W +
Sbjct: 3   QTLEEVNIEV--NTGKEITGKIVKCDIKPRQLKVVVSGEV-IIDGELNEVVHPDDSTWTV 173

Query: 237 EDGKVVTVHLEKINKMEWWNRLVTSDPEINTKKINPENSKLSDLDSETRSMVEKMMYDQR 296
           ED KV+ + L K         L T+D        +   S L+D                 
Sbjct: 174 EDRKVLRICLSK--------SLTTAD--------HCWKSLLTD----------------- 254

Query: 297 QKSMGLPTSDEQKKQEILKKFMDQHPEMDFSKAKFN 332
                L T DE +K+  L++F  ++P  DFS A   
Sbjct: 255 AYPADLLTLDEMQKKLTLQRFQFENPGFDFSGASVT 362
>09499
          Length = 855

 Score = 42.4 bits (98), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 17/28 (60%), Positives = 21/28 (75%)
 Frame = +1

Query: 10 FDGMLLAMAQQHEGGVQELVNTFFSFLR 37
          FDGML+ MAQQ EGG+ EL+ TF  F +
Sbjct: 1  FDGMLMTMAQQCEGGIHELLGTFLGFCK 84

 Score = 30.8 bits (68), Expect = 0.73,   Method: Compositional matrix adjust.
 Identities = 28/104 (26%), Positives = 39/104 (37%), Gaps = 4/104 (3%)
 Frame = +2

Query: 22  EGGVQELVNTFFSFLRRKTDFFIGGEEGMAEKLITQTFNHHNQXXXXXXXXX----XXXX 77
           EG +   V+++ S   ++TDFF G     AE+L+  TF  H                   
Sbjct: 41  EGFMSCWVHSWVS--AKETDFFTGTGSAQAEELVMSTFRKHQATAQKLKKEQMEKEKKKA 214

Query: 78  XXXXXXXXXXXXXXXXXXXXXXPGPQIKELTDEEAERLQLEIDQ 121
                                   P+IKELTD EAE L+ E+ Q
Sbjct: 215 EKKAKEREEAERKRKEAEQKTEEEPKIKELTDAEAEALEKELSQ 346
>23848
          Length = 717

 Score = 28.1 bits (61), Expect = 4.6,   Method: Compositional matrix adjust.
 Identities = 15/38 (39%), Positives = 22/38 (57%), Gaps = 2/38 (5%)
 Frame = +3

Query: 17  MAQQHEGGVQELVNTF--FSFLRRKTDFFIGGEEGMAE 52
           + +  EGG+ +L N+   FSF RRK   F+ G  G +E
Sbjct: 279 IIRNREGGMGKLGNSVIGFSFARRKVQRFVAGRLGDSE 392
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6755202|ref|NP_036101.1| proteasome beta 3 subunit
[Mus musculus]
         (205 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

09425                                                                 343   3e-95
06516                                                                  76   1e-14
00497                                                                  53   9e-08
14312                                                                  30   0.65 
03425                                                                  28   2.8  
>09425
          Length = 1898

 Score =  343 bits (879), Expect = 3e-95,   Method: Compositional matrix adjust.
 Identities = 155/205 (75%), Positives = 185/205 (90%)
 Frame = -3

Query: 1    MSIMSYNGGAVMAMKGKNCVAIAADRRFGIQAQMVTTDFQKIFPMGDRLYIGLAGLATDV 60
            MSI++YNG A++AMKGK+CVAIAADRRFG+QAQ V+ DF K+F MG  L+IGL GLATDV
Sbjct: 1836 MSILAYNGAAIIAMKGKDCVAIAADRRFGVQAQTVSMDFDKVFEMGPHLFIGLPGLATDV 1657

Query: 61   QTVAQRLKFRLNLYELKEGRQIKPYTLMSMVANLLYEKRFGPYYTEPVIAGLDPKTFKPF 120
            QTV+QRLKFRLNLYEL+E R+IKP T MSMV+NLLYE+RFGPY+ EPVIAGL+PKTFKP+
Sbjct: 1656 QTVSQRLKFRLNLYELRENRRIKPQTFMSMVSNLLYERRFGPYFVEPVIAGLEPKTFKPY 1477

Query: 121  ICSLDLIGCPMVTDDFVVSGTCSEQMYGMCESLWEPNMDPEHLFETISQAMLNAVDRDAV 180
            I S+DLIGCPMVT+DFVVSGTCSEQMYGMCESLWEP+++P+ LFETISQA++NA DRDAV
Sbjct: 1476 IASMDLIGCPMVTEDFVVSGTCSEQMYGMCESLWEPDLEPDDLFETISQALMNAFDRDAV 1297

Query: 181  SGMGVIVHVIEKDKITTRTLKARMD 205
            SG G +V++IEKDK+T + LK RMD
Sbjct: 1296 SGWGGVVYIIEKDKVTKKLLKTRMD 1222
>06516
          Length = 835

 Score = 75.9 bits (185), Expect = 1e-14,   Method: Compositional matrix adjust.
 Identities = 53/194 (27%), Positives = 98/194 (50%)
 Frame = +1

Query: 7   NGGAVMAMKGKNCVAIAADRRFGIQAQMVTTDFQKIFPMGDRLYIGLAGLATDVQTVAQR 66
            G  +MA++ ++ V I AD R    A +      K+  + DR+Y   +G A D Q +A  
Sbjct: 118 TGTTIMAVEYEDGVVIGADSRTTTGAYIANRVTDKLTKVTDRIYCCRSGSAADTQAIADI 297

Query: 67  LKFRLNLYELKEGRQIKPYTLMSMVANLLYEKRFGPYYTEPVIAGLDPKTFKPFICSLDL 126
           +K+ L+ Y ++ G + +  T  ++   L Y+ R        ++AG D +T    + S+  
Sbjct: 298 VKYHLDFYRMEMGEEPQVQTAANVFRELCYDNR-DSLTAGIIVAGWDKRTGGQ-VYSVP- 468

Query: 127 IGCPMVTDDFVVSGTCSEQMYGMCESLWEPNMDPEHLFETISQAMLNAVDRDAVSGMGVI 186
           IG  +    F + G+ S  +YG  ++ ++P+M  +   + +SQA+  A++RD  SG  + 
Sbjct: 469 IGGMLQRQPFAIGGSGSTYLYGYVDAQFKPSMKKDDCLKFVSQAVSLAINRDGSSGGIIR 648

Query: 187 VHVIEKDKITTRTL 200
           + VI K+ +   TL
Sbjct: 649 MAVINKEGVERVTL 690
>00497
          Length = 1184

 Score = 52.8 bits (125), Expect = 9e-08,   Method: Compositional matrix adjust.
 Identities = 40/163 (24%), Positives = 77/163 (47%), Gaps = 17/163 (10%)
 Frame = +3

Query: 60  VQTVAQRLKFRLNLYELKEGRQIKPYTLMSMVANLLYEKRFGPYYTEPVIAGLDPKTFKP 119
           V T+ + ++ RL ++     +++   ++ +M++ +LY +RF PYY   ++AGLD +  K 
Sbjct: 3   VLTLTKVVETRLKMFSYIHNKEMDTSSVAAMLSTILYYRRFFPYYXYNIVAGLDTEG-KG 179

Query: 120 FICSLDLIGCPMVTDDFVVSGTCSEQMYGMCESLWEPNMDPEHLFET--------ISQA- 170
            + S D +G     + +   G+ S        S+ +P +D +   +         +SQA 
Sbjct: 180 CVFSFDPVGS-YERETYRAGGSAS--------SMLQPLLDNQIGMKNQAGAKQVPLSQAK 332

Query: 171 --------MLNAVDRDAVSGMGVIVHVIEKDKITTRTLKARMD 205
                     +A +RD  +G  V++HV+ K  +T  T   R D
Sbjct: 333 AVALVKDVFTSAAERDINTGDAVVIHVVSKQGVTKTTFPLRRD 461
>14312
          Length = 1773

 Score = 30.0 bits (66), Expect = 0.65,   Method: Compositional matrix adjust.
 Identities = 15/31 (48%), Positives = 20/31 (64%)
 Frame = +1

Query: 44  PMGDRLYIGLAGLATDVQTVAQRLKFRLNLY 74
           P+  RLY+ LA  A DV  V+QRL+   +LY
Sbjct: 409 PLPQRLYLTLARAARDVPGVSQRLERPRHLY 501
>03425
          Length = 933

 Score = 28.1 bits (61), Expect = 2.8,   Method: Compositional matrix adjust.
 Identities = 16/60 (26%), Positives = 28/60 (46%)
 Frame = +3

Query: 136 FVVSGTCSEQMYGMCESLWEPNMDPEHLFETISQAMLNAVDRDAVSGMGVIVHVIEKDKI 195
           FV  G+ S       E  ++P+M  +   + +  A+   +  D  SG  + + VI KDK+
Sbjct: 93  FVTMGSGSLAAMATFEDRFKPDMSRDEAMKLVRDAIAAGIFNDLGSGSNIDLCVITKDKV 272
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|33468961|ref|NP_061368.1| tripartite motif protein 3
[Mus musculus]
         (744 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

03572                                                                 343   1e-94
03602                                                                 102   5e-22
11956                                                                  89   8e-18
29117                                                                  73   5e-13
07490                                                                  64   1e-10
20109                                                                  60   3e-09
20514                                                                  54   2e-07
18021                                                                  38   6e-06
27774                                                                  48   2e-05
27230                                                                  47   3e-05
13043                                                                  45   2e-04
14625                                                                  44   2e-04
33436                                                                  40   0.002
18540                                                                  40   0.003
20704                                                                  38   0.011
20092                                                                  38   0.015
10203                                                                  35   0.081
06811                                                                  34   0.19 
03240                                                                  34   0.20 
27368                                                                  34   0.23 
14716                                                                  33   0.36 
12312                                                                  33   0.44 
18689                                                                  33   0.51 
17930                                                                  32   0.64 
23915                                                                  32   1.3  
29288                                                                  32   1.3  
07293                                                                  31   1.4  
15938                                                                  31   1.6  
27237                                                                  31   1.7  
33593                                                                  31   1.7  
31249                                                                  31   1.9  
08613                                                                  30   3.7  
14417                                                                  29   5.7  
07523                                                                  29   6.7  
16700                                                                  29   7.5  
09947                                                                  29   7.6  
27286                                                                  29   8.5  
>03572
          Length = 776

 Score =  343 bits (881), Expect = 1e-94,   Method: Compositional matrix adjust.
 Identities = 157/218 (72%), Positives = 185/218 (84%)
 Frame = -1

Query: 527 GRSPGQLQRPTGVAVDTNGDIIVADYDNRWVSIFSPEGKFKTKIGAGRLMGPKGVAVDRN 586
           GR  G++QRPTGVAV  NG+ +VADYDN+WVS+F+P+GK+ +KIG GRL GPKGVAVD N
Sbjct: 770 GRVAGKIQRPTGVAVTLNGNYLVADYDNKWVSVFAPDGKYISKIGTGRLQGPKGVAVDNN 591

Query: 587 GHIIVVDNKSCCVFTFQPNGKLVGRFGGRGATDRHFAGPHFVAVNNKNEIVVTDFHNHSV 646
           GHIIVVDNK+  V  FQ NGKL+ +FG RG  D  FAGPH+ A+   N+I+V+DFHNHSV
Sbjct: 590 GHIIVVDNKASSVLVFQNNGKLLHKFGSRGNEDYQFAGPHYAAITKNNDIIVSDFHNHSV 411

Query: 647 KVYSADGEFLFKFGSHGEGNGQFNAPTGVAVDSNGNIIVADWGNSRIQVFDSSGSFLSYI 706
           KV+ +DG FLF FGS GEGNGQFNAPTGVAVD NG+I+VADWGNSRIQVFD++GSFLSY+
Sbjct: 410 KVFGSDGSFLFCFGSMGEGNGQFNAPTGVAVDPNGHILVADWGNSRIQVFDANGSFLSYV 231

Query: 707 NTSAEPLYGPQGLALTSDGHVVVADAGNHCFKAYRYLQ 744
           NTSAEPLYGPQGL +TSDG VVVAD+GNHC K Y+YLQ
Sbjct: 230 NTSAEPLYGPQGLGVTSDGQVVVADSGNHCIKFYKYLQ 117

 Score = 94.7 bits (234), Expect = 1e-19,   Method: Compositional matrix adjust.
 Identities = 48/131 (36%), Positives = 75/131 (57%), Gaps = 2/131 (1%)
 Frame = -1

Query: 471 ELVFRVGSRGREKGEFTNLQGVSAASSGRIVVADSNNQCIQVFSNEGQFKFRFGVRGRSP 530
           +L+ + GSRG E  +F      +   +  I+V+D +N  ++VF ++G F F FG  G   
Sbjct: 530 KLLHKFGSRGNEDYQFAGPHYAAITKNNDIIVSDFHNHSVKVFGSDGSFLFCFGSMGEGN 351

Query: 531 GQLQRPTGVAVDTNGDIIVADYDNRWVSIFSPEGKFKTKIG--AGRLMGPKGVAVDRNGH 588
           GQ   PTGVAVD NG I+VAD+ N  + +F   G F + +   A  L GP+G+ V  +G 
Sbjct: 350 GQFNAPTGVAVDPNGHILVADWGNSRIQVFDANGSFLSYVNTSAEPLYGPQGLGVTSDGQ 171

Query: 589 IIVVDNKSCCV 599
           ++V D+ + C+
Sbjct: 170 VVVADSGNHCI 138

 Score = 93.2 bits (230), Expect = 4e-19,   Method: Compositional matrix adjust.
 Identities = 62/199 (31%), Positives = 95/199 (47%), Gaps = 5/199 (2%)
 Frame = -1

Query: 469 EDELVFRVGSRGREKGEFTNLQGVSAASSGRIVVADSNNQCIQVFSNEGQFKFRFGVRGR 528
           + + + ++G+ GR +G     +GV+  ++G I+V D+    + VF N G+   +FG RG 
Sbjct: 662 DGKYISKIGT-GRLQGP----KGVAVDNNGHIIVVDNKASSVLVFQNNGKLLHKFGSRGN 498

Query: 529 SPGQLQRPTGVAVDTNGDIIVADYDNRWVSIFSPEGKFKTKIGA-----GRLMGPKGVAV 583
              Q   P   A+  N DIIV+D+ N  V +F  +G F    G+     G+   P GVAV
Sbjct: 497 EDYQFAGPHYAAITKNNDIIVSDFHNHSVKVFGSDGSFLFCFGSMGEGNGQFNAPTGVAV 318

Query: 584 DRNGHIIVVDNKSCCVFTFQPNGKLVGRFGGRGATDRHFAGPHFVAVNNKNEIVVTDFHN 643
           D NGHI+V D  +  +  F  NG  +        +     GP  + V +  ++VV D  N
Sbjct: 317 DPNGHILVADWGNSRIQVFDANGSFLSYV---NTSAEPLYGPQGLGVTSDGQVVVADSGN 147

Query: 644 HSVKVYSADGEFLFKFGSH 662
           H +K Y     F   F  H
Sbjct: 146 HCIKFYKYLQ*FHLPFNKH 90
>03602
          Length = 1190

 Score =  102 bits (254), Expect = 5e-22,   Method: Compositional matrix adjust.
 Identities = 76/243 (31%), Positives = 114/243 (46%), Gaps = 14/243 (5%)
 Frame = -3

Query: 501  VVADSNNQCIQVFSNEGQFKFRFGVRGRSPGQLQRPTGVAVDTN-GDIIVADYDNRWVSI 559
            VV+DS +  I VF + G+ K                T +  D    D+ V+  +   V +
Sbjct: 1185 VVSDSGSGRIFVFYSHGEVK----------------TTITCDCRIKDVAVSRRNEILVVV 1054

Query: 560  FSPEGKFKTKIGAGRLMG----------PKGVAVDRNGHIIVVDNKSCCVFTFQPNGKLV 609
              P    +     G L+G          P G+    NG  ++   ++  VF F    K  
Sbjct: 1053 NKPSVALQIYTVTGHLLGEHGKFITHEDPHGITALANGGAVITSKQNQNVFIFTDQLKYS 874

Query: 610  GRFGGRGATDRHFAGPHFVAVNNKNEIVVTDFHNHSVKVYSADGEFLFKFGSHGEGNGQF 669
             +FG +G  D +F  P FV  N++N+IVVTD  N +V+V++  GE  F+FG  G   G+F
Sbjct: 873  SKFGRKGTGDGYFHSPQFVTTNSRNQIVVTDDMNDNVQVFNWLGELKFRFGRSGSKPGEF 694

Query: 670  NAPTGVAVDSNGNIIVADWGNSRIQVFDSSGSFLSYINTSAEPL---YGPQGLALTSDGH 726
              P GVA DS+ N+ VAD GN R+Q F+  G + + + +    L     P  +A+TS G 
Sbjct: 693  VRPMGVATDSDDNMYVADSGNCRVQKFNCKGVYQNLVVSDTHCLGQDVXPVNVAVTSAGD 514

Query: 727  VVV 729
            V V
Sbjct: 513  VAV 505

 Score = 72.0 bits (175), Expect = 9e-13,   Method: Compositional matrix adjust.
 Identities = 46/130 (35%), Positives = 71/130 (54%), Gaps = 7/130 (5%)
 Frame = -3

Query: 470 DELVF--RVGSRGREKGEFTNLQGVSAASSGRIVVADSNNQCIQVFSNEGQFKFRFGVRG 527
           D+L +  + G +G   G F + Q V+  S  +IVV D  N  +QVF+  G+ KFRFG  G
Sbjct: 891 DQLKYSSKFGRKGTGDGYFHSPQFVTTNSRNQIVVTDDMNDNVQVFNWLGELKFRFGRSG 712

Query: 528 RSPGQLQRPTGVAVDTNGDIIVADYDNRWVSIFSPEGKFKTKIGA-----GRLMGPKGVA 582
             PG+  RP GVA D++ ++ VAD  N  V  F+ +G ++  + +     G+ + P  VA
Sbjct: 711 SKPGEFVRPMGVATDSDDNMYVADSGNCRVQKFNCKGVYQNLVVSDTHCLGQDVXPVNVA 532

Query: 583 VDRNGHIIVV 592
           V   G + V+
Sbjct: 531 VTSAGDVAVL 502

 Score = 69.7 bits (169), Expect = 5e-12,   Method: Compositional matrix adjust.
 Identities = 57/191 (29%), Positives = 92/191 (48%), Gaps = 4/191 (2%)
 Frame = -3

Query: 548  IVADYDNRWVSIFSPEGKFKTKIGAGRLMGPKGVAVDRNGHIIVVDNK-SCCVFTFQPNG 606
            +V+D  +  + +F   G+ KT I     +  K VAV R   I+VV NK S  +  +   G
Sbjct: 1185 VVSDSGSGRIFVFYSHGEVKTTITCDCRI--KDVAVSRRNEILVVVNKPSVALQIYTVTG 1012

Query: 607  KLVGRFGGRGATDRHFAGPHFVAVNNKNEIVVTDFHNHSVKVYSADGEFLFKFGSHGEGN 666
             L+G  G     +     PH +        V+T   N +V +++   ++  KFG  G G+
Sbjct: 1011 HLLGEHGKFITHED----PHGITALANGGAVITSKQNQNVFIFTDQLKYSSKFGRKGTGD 844

Query: 667  GQFNAPTGVAVDSNGNIIVADWGNSRIQVFDSSGSF-LSYINTSAEP--LYGPQGLALTS 723
            G F++P  V  +S   I+V D  N  +QVF+  G     +  + ++P     P G+A  S
Sbjct: 843  GYFHSPQFVTTNSRNQIVVTDDMNDNVQVFNWLGELKFRFGRSGSKPGEFVRPMGVATDS 664

Query: 724  DGHVVVADAGN 734
            D ++ VAD+GN
Sbjct: 663  DDNMYVADSGN 631
>11956
          Length = 501

 Score = 88.6 bits (218), Expect = 8e-18,   Method: Compositional matrix adjust.
 Identities = 52/131 (39%), Positives = 70/131 (53%)
 Frame = -3

Query: 573 GRLMGPKGVAVDRNGHIIVVDNKSCCVFTFQPNGKLVGRFGGRGATDRHFAGPHFVAVNN 632
           G    P+G+AV  +  I+V D+ +  V  F  NG  V  FG  G  +  F     VAVN 
Sbjct: 490 GSFTWPRGLAVGPDNSIVVADSSNHRVQVFDSNGIFVKEFGEYGNGEGEFDCLAGVAVNR 311

Query: 633 KNEIVVTDFHNHSVKVYSADGEFLFKFGSHGEGNGQFNAPTGVAVDSNGNIIVADWGNSR 692
             + ++ D +NH ++V    G FL  FGS G  +G+FN P GV  D+ G I V D  N R
Sbjct: 310 IGQYIIADRYNHRIQVLDPQGRFLRAFGSQGIADGKFNYPWGVTTDALGFIYVCDKENHR 131

Query: 693 IQVFDSSGSFL 703
           +QVF S GSF+
Sbjct: 130 VQVFQSDGSFV 98

 Score = 87.4 bits (215), Expect = 2e-17,   Method: Compositional matrix adjust.
 Identities = 54/151 (35%), Positives = 75/151 (49%), Gaps = 5/151 (3%)
 Frame = -3

Query: 482 EKGEFTNLQGVSAASSGRIVVADSNNQCIQVFSNEGQFKFRFGVRGRSPGQLQRPTGVAV 541
           E G FT  +G++      IVVADS+N  +QVF + G F   FG  G   G+     GVAV
Sbjct: 496 EPGSFTWPRGLAVGPDNSIVVADSSNHRVQVFDSNGIFVKEFGEYGNGEGEFDCLAGVAV 317

Query: 542 DTNGDIIVADYDNRWVSIFSPEGKFKTKIGA-----GRLMGPKGVAVDRNGHIIVVDNKS 596
           +  G  I+AD  N  + +  P+G+F    G+     G+   P GV  D  G I V D ++
Sbjct: 316 NRIGQYIIADRYNHRIQVLDPQGRFLRAFGSQGIADGKFNYPWGVTTDALGFIYVCDKEN 137

Query: 597 CCVFTFQPNGKLVGRFGGRGATDRHFAGPHF 627
             V  FQ +G  VG+FG  G  +     PH+
Sbjct: 136 HRVQVFQSDGSFVGKFGSCGRGEGQLEHPHY 44

 Score = 84.3 bits (207), Expect = 1e-16,   Method: Compositional matrix adjust.
 Identities = 53/148 (35%), Positives = 70/148 (47%), Gaps = 5/148 (3%)
 Frame = -3

Query: 530 PGQLQRPTGVAVDTNGDIIVADYDNRWVSIFSPEGKFKTKIGA-----GRLMGPKGVAVD 584
           PG    P G+AV  +  I+VAD  N  V +F   G F  + G      G      GVAV+
Sbjct: 493 PGSFTWPRGLAVGPDNSIVVADSSNHRVQVFDSNGIFVKEFGEYGNGEGEFDCLAGVAVN 314

Query: 585 RNGHIIVVDNKSCCVFTFQPNGKLVGRFGGRGATDRHFAGPHFVAVNNKNEIVVTDFHNH 644
           R G  I+ D  +  +    P G+ +  FG +G  D  F  P  V  +    I V D  NH
Sbjct: 313 RIGQYIIADRYNHRIQVLDPQGRFLRAFGSQGIADGKFNYPWGVTTDALGFIYVCDKENH 134

Query: 645 SVKVYSADGEFLFKFGSHGEGNGQFNAP 672
            V+V+ +DG F+ KFGS G G GQ   P
Sbjct: 133 RVQVFQSDGSFVGKFGSCGRGEGQLEHP 50

 Score = 67.8 bits (164), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 45/137 (32%), Positives = 64/137 (46%), Gaps = 5/137 (3%)
 Frame = -3

Query: 472 LVFRVGSRGREKGEFTNLQGVSAASSGRIVVADSNNQCIQVFSNEGQFKFRFGVRGRSPG 531
            V   G  G  +GEF  L GV+    G+ ++AD  N  IQV   +G+F   FG +G + G
Sbjct: 385 FVKEFGEYGNGEGEFDCLAGVAVNRIGQYIIADRYNHRIQVLDPQGRFLRAFGSQGIADG 206

Query: 532 QLQRPTGVAVDTNGDIIVADYDNRWVSIFSPEGKFKTKIGA-----GRLMGPKGVAVDRN 586
           +   P GV  D  G I V D +N  V +F  +G F  K G+     G+L  P        
Sbjct: 205 KFNYPWGVTTDALGFIYVCDKENHRVQVFQSDGSFVGKFGSCGRGEGQLEHP-------- 50

Query: 587 GHIIVVDNKSCCVFTFQ 603
            H   ++ +SC  F F+
Sbjct: 49  -HYSRIEYESCYCFRFE 2
>29117
          Length = 320

 Score = 72.8 bits (177), Expect = 5e-13,   Method: Composition-based stats.
 Identities = 31/78 (39%), Positives = 45/78 (57%), Gaps = 3/78 (3%)
 Frame = +1

Query: 12  VQPMDKQFLVCSICLDRYRCPKVLPCLHTFCERCLQNYIPPQSL---TLSCPVCRQTSIL 68
           V+ +   FL C +CL  +  PK+LPC HTFC  CL+ Y+   +       CP+C++T I+
Sbjct: 46  VEGLKDDFLTCPLCLQLFTEPKILPCQHTFCSHCLRKYLDHNTFLQWQCVCPLCKKTCIV 225

Query: 69  PEQGVSALQNNFFISSLM 86
            E  V+ L NNF I  L+
Sbjct: 226 REGDVTKLPNNFLIVGLL 279
>07490
          Length = 1665

 Score = 64.3 bits (155), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 64/253 (25%), Positives = 104/253 (41%), Gaps = 47/253 (18%)
 Frame = -2

Query: 32   PKVLPCLHTFCERCLQNYIPPQSLTLSCPVCRQTSILPEQ-------GVSALQNNFFISS 84
            PK+LPC H FC+ CL  ++  Q    +CP CR   I P +       GV +L  N  +  
Sbjct: 1652 PKLLPCGHHFCKACLLRWVESQGWRAACPFCRALIISPTKCVDSLVDGVESLPTNHGLEE 1473

Query: 85   LMEAMQ--QAPE------------------------GAHDPEDP----HPLSAV------ 108
            L++A Q  ++P                         G  D  D     HP+ AV      
Sbjct: 1472 LVKARQVVRSPNVCSRCDGSVEAVSYCIQCEAKMCPGCQDTHDQTTXGHPVEAVRTLTEA 1293

Query: 109  --AGRP-LSCPNHEGKTMEFYCEACETAMCGECRAGEHR-EHGTVLLRDVVEQHKAALQR 164
              AG+  + C  H  +   +YC + +T  C +C   +H    G + +  +    ++ LQ 
Sbjct: 1292 KLAGKHVVKCEKHPDRPANYYCRSHQTLACDQCAQDDHSCCSGYLAISKLGPLARSRLQE 1113

Query: 165  QLEAVRGRLPQLSAAIALVGGISQQLQERKAEALAQISAAFEDLEQALQQRKQALVSDLE 224
             ++ ++     L+  I L    S +  ER       I+ AF+DLE  L+ ++Q L+  L 
Sbjct: 1112 TVDVMKQNAANLAYQIKL-AKYSYRETER------DINEAFDDLEDRLESQRQLLLDTLH 954

Query: 225  SICGAKQKVLQTQ 237
             +  A    L+T 
Sbjct: 953  EMKDASTGSLETH 915
>20109
          Length = 418

 Score = 60.1 bits (144), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 28/71 (39%), Positives = 40/71 (56%), Gaps = 1/71 (1%)
 Frame = -1

Query: 13  QPMDKQFLVCSICLDRYRCPKVLPCLHTFCERCLQNYIPPQ-SLTLSCPVCRQTSILPEQ 71
           Q   K+ + C++C + +R P+ LPC HTFC +CL +      S T  CPVCR    +P  
Sbjct: 358 QNASKERVTCTVCFEVFRDPRFLPCHHTFCLQCLADLASRSPSSTFPCPVCRHHVTVPHG 179

Query: 72  GVSALQNNFFI 82
            VS  Q NF++
Sbjct: 178 SVSTFQTNFYL 146
>20514
          Length = 803

 Score = 54.3 bits (129), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 46/153 (30%), Positives = 65/153 (42%), Gaps = 29/153 (18%)
 Frame = -2

Query: 538 GVAVDTNGDIIVADYDNR-W----------------------VSIFSPEGKFKTKIGAGR 574
           G+A+D +G+I +    +R W                      + I  P+G F  K GAGR
Sbjct: 547 GLAIDNDGNIYIFHRGDRSWDQTSFDMNKHFTKQDQPITQNTILILGPDGVFVRKFGAGR 368

Query: 575 LMGPKGVAVDRNGHIIVVDNKSCCVFTFQPNGK-----LVGRFGGRGATDRHFAGPHFVA 629
              P G+ VD  G+I + D     VF   P G       +G     G    HF  P  VA
Sbjct: 367 FFMPHGIEVDHAGNIWLTDVALHQVFRI-PAGSQEADLTLGERFVHGDDHTHFCQPSDVA 191

Query: 630 VNNKNEIVVTD-FHNHSVKVYSADGEFLFKFGS 661
           V    E  V+D + N  +  +S DG+FL ++GS
Sbjct: 190 VLPSGEFFVSDGYCNSRIMKFSKDGQFLKQWGS 92

 Score = 44.3 bits (103), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 40/131 (30%), Positives = 57/131 (43%), Gaps = 8/131 (6%)
 Frame = -2

Query: 581 VAVDRNGHIIVVDN--KSCCVFTFQPNGKLVGRFG-GRGATDRHFAGPHFVAVNNKNEIV 637
            + D N H    D       +    P+G  V +FG GR      F  PH + V++   I 
Sbjct: 481 TSFDMNKHFTKQDQPITQNTILILGPDGVFVRKFGAGR------FFMPHGIEVDHAGNIW 320

Query: 638 VTDFHNHSV-KVYSADGEFLFKFGS---HGEGNGQFNAPTGVAVDSNGNIIVAD-WGNSR 692
           +TD   H V ++ +   E     G    HG+ +  F  P+ VAV  +G   V+D + NSR
Sbjct: 319 LTDVALHQVFRIPAGSQEADLTLGERFVHGDDHTHFCQPSDVAVLPSGEFFVSDGYCNSR 140

Query: 693 IQVFDSSGSFL 703
           I  F   G FL
Sbjct: 139 IMKFSKDGQFL 107
>18021
          Length = 485

 Score = 37.7 bits (86), Expect(2) = 6e-06,   Method: Composition-based stats.
 Identities = 14/39 (35%), Positives = 24/39 (61%)
 Frame = +1

Query: 55  LTLSCPVCRQTSILPEQGVSALQNNFFISSLMEAMQQAP 93
           ++ +CP C++   +PE+GV+A Q NF+I +  E     P
Sbjct: 118 VSFACPTCKKMVAVPEKGVAAFQTNFYIVTEREQPPATP 234

 Score = 30.8 bits (68), Expect(2) = 6e-06,   Method: Compositional matrix adjust.
 Identities = 23/73 (31%), Positives = 32/73 (43%), Gaps = 6/73 (8%)
 Frame = +3

Query: 107 AVAGRPLSCP-----NHEGKTMEFYCEACETAMCGECRAGEHREHGTVLLRDVVEQHKAA 161
           A    PL C        E +   F CE C+  MC  CR    R+H T++  + V  HK+ 
Sbjct: 216 AATSHPLPCQMCEEVEDEARDAVFVCEKCQQRMCQPCR----RKHDTII--NKVANHKST 377

Query: 162 -LQRQLEAVRGRL 173
                L+A RG +
Sbjct: 378 KYSPWLQAARGTM 416
>27774
          Length = 448

 Score = 47.8 bits (112), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 21/39 (53%), Positives = 28/39 (71%)
 Frame = -3

Query: 654 EFLFKFGSHGEGNGQFNAPTGVAVDSNGNIIVADWGNSR 692
           +F+ KFG +G  +GQF  P+GVA+DS   +IVAD  NSR
Sbjct: 119 QFVTKFGEYGNSHGQFTEPSGVAIDSENRLIVADTNNSR 3

 Score = 39.7 bits (91), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 18/37 (48%), Positives = 24/37 (64%)
 Frame = -3

Query: 518 QFKFRFGVRGRSPGQLQRPTGVAVDTNGDIIVADYDN 554
           QF  +FG  G S GQ   P+GVA+D+   +IVAD +N
Sbjct: 119 QFVTKFGEYGNSHGQFTEPSGVAIDSENRLIVADTNN 9

 Score = 33.9 bits (76), Expect = 0.22,   Method: Compositional matrix adjust.
 Identities = 15/37 (40%), Positives = 22/37 (59%)
 Frame = -3

Query: 471 ELVFRVGSRGREKGEFTNLQGVSAASSGRIVVADSNN 507
           + V + G  G   G+FT   GV+  S  R++VAD+NN
Sbjct: 119 QFVTKFGEYGNSHGQFTEPSGVAIDSENRLIVADTNN 9
>27230
          Length = 583

 Score = 47.0 bits (110), Expect = 3e-05,   Method: Composition-based stats.
 Identities = 26/62 (41%), Positives = 36/62 (58%)
 Frame = -1

Query: 358 GSAELCAEITGPDGVRLAVPVVDHKNGTYELVYTARTEGDLLLSVLLYGQPVRGSPFRVR 417
           G  E+ A +T P G +L   V + K+GTY ++YT   EG   L V   G P+ GSPF+V 
Sbjct: 247 GQGEVEAILTTPSGRKLQTLVDNMKDGTYPVLYTPMEEGPQSLDVTYKGIPIPGSPFQVN 68

Query: 418 AL 419
           A+
Sbjct: 67  AV 62
>13043
          Length = 1574

 Score = 44.7 bits (104), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 32/97 (32%), Positives = 49/97 (50%), Gaps = 1/97 (1%)
 Frame = +3

Query: 328 TGEGLRQALVGQ-PASLTVTTKDKDGRLVRTGSAELCAEITGPDGVRLAVPVVDHKNGTY 386
           +G G+R+++    PA  TV T+D        G A+L   +  PDG  +     ++++GTY
Sbjct: 507 SGPGVRRSVPASLPAQFTVDTRD-------AGVADLECMVQRPDGSFIKPYFQNNEDGTY 665

Query: 387 ELVYTARTEGDLLLSVLLYGQPVRGSPFRVRALRPGD 423
           +++YT    G   + V   GQ V  SPF V A   GD
Sbjct: 666 DVIYTPEDLGVYDIIVKYDGQDVPRSPFNVEATPLGD 776

 Score = 40.0 bits (92), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 36/114 (31%), Positives = 47/114 (41%), Gaps = 3/114 (2%)
 Frame = +3

Query: 329 GEGLRQALVGQ--PASLTVTTKDKDGRLVRTGSAELCAEITGP-DGVRLAVPVVDHKNGT 385
           G GL  + V    PA  TV  +D        G A L    T P  G +    +V  + G 
Sbjct: 216 GPGLDASEVAANLPAVFTVDARD-------AGEAPLDVTFTDPLSGAQQEAEIVPVEEGL 374

Query: 386 YELVYTARTEGDLLLSVLLYGQPVRGSPFRVRALRPGDLPPSPDDVKRRVKSPG 439
           Y+  Y  R EG   + V   G+PV  SPF ++ L      P  D  K +V  PG
Sbjct: 375 YQATYMPRAEGKCKVDVKYGGKPVPNSPFHMQVL------PGVDPSKVKVSGPG 518

 Score = 32.7 bits (73), Expect = 0.56,   Method: Compositional matrix adjust.
 Identities = 15/44 (34%), Positives = 24/44 (54%)
 Frame = +3

Query: 380 DHKNGTYELVYTARTEGDLLLSVLLYGQPVRGSPFRVRALRPGD 423
           D+++GT  + Y     G   +SVL   +P++ SPF V+   P D
Sbjct: 63  DNRDGTCRVEYYPTKPGKYDISVLFGDKPIKDSPFSVKIQNPVD 194

 Score = 30.0 bits (66), Expect = 3.2,   Method: Compositional matrix adjust.
 Identities = 26/132 (19%), Positives = 53/132 (40%), Gaps = 2/132 (1%)
 Frame = +3

Query: 290 PHENAQLELVLEVDG--LRRSVLNLGALLTTSATAHETVATGEGLRQALVGQPASLTVTT 347
           P +    +++++ DG  + RS  N+ A  T    A +   T    R   + +   +TV  
Sbjct: 681 PEDLGVYDIIVKYDGQDVPRSPFNVEA--TPLGDASQCRITDGAERVIPIEKETVITVDA 854

Query: 348 KDKDGRLVRTGSAELCAEITGPDGVRLAVPVVDHKNGTYELVYTARTEGDLLLSVLLYGQ 407
            D        G   +   I  P G  + + +VD  +GT+ + +  +  G+ ++ +   G 
Sbjct: 855 AD-------AGKGSVTCRIRSPSGSDIDIDIVDQGDGTFTISFIPQYAGEYIIEIKFGGN 1013

Query: 408 PVRGSPFRVRAL 419
            V    +   A+
Sbjct: 1014FVPDGQYTAEAV 1049
>14625
          Length = 846

 Score = 44.3 bits (103), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 30/130 (23%), Positives = 58/130 (44%)
 Frame = +3

Query: 113 LSCPNHEGKTMEFYCEACETAMCGECRAGEHREHGTVLLRDVVEQHKAALQRQLEAVRGR 172
           + C  H  + +  +CE CE   C +C+  +H+EH    L++  E +KA L   L  ++ R
Sbjct: 252 MLCRVHPKEKLTLFCEKCEVLTCRDCQLLQHQEHKYQFLQEAAESYKAKLTGSLSLMKDR 431

Query: 173 LPQLSAAIALVGGISQQLQERKAEALAQISAAFEDLEQALQQRKQALVSDLESICGAKQK 232
              L      +     +++  K +    I    + + +A++    A++S L S   A  K
Sbjct: 432 REVLWRYQTEIEERLSKVKREKNDLQQDILRQADVIVKAVRTAVWAVLSSLHSFTDAAAK 611

Query: 233 VLQTQLDTLR 242
            L  ++  +R
Sbjct: 612 RLSREVGDVR 641
>33436
          Length = 583

 Score = 40.4 bits (93), Expect = 0.002,   Method: Composition-based stats.
 Identities = 16/46 (34%), Positives = 25/46 (54%)
 Frame = -1

Query: 20  LVCSICLDRYRCPKVLPCLHTFCERCLQNYIPPQSLTLSCPVCRQT 65
           L CSICL+    P    C H FC  C+  ++  +  ++ CP+C+ T
Sbjct: 406 LECSICLELMTSPVATKCEHYFCRFCITEFLEKKR-SVPCPLCKAT 272
>18540
          Length = 988

 Score = 40.0 bits (92), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 33/110 (30%), Positives = 51/110 (46%), Gaps = 9/110 (8%)
 Frame = +3

Query: 621 HFAGPHFVAVNNKNEIVVTD-FHNHSVKVYSADGEFLFKFGSHGEGNGQ-------FNAP 672
           HF  P  VAV    +  V+D + N  V  +S +G  L ++G   +   +       F  P
Sbjct: 78  HFCKPTDVAVLASGDFFVSDGYCNSRVMKFSKEGNLLKQWGRPDQFRARIQPQPNVFTIP 257

Query: 673 TGVAVDSNGNII-VADWGNSRIQVFDSSGSFLSYINTSAEPLYGPQGLAL 721
             +A+  + N++ VAD  N RIQ FD  G+F   I       +GP+  A+
Sbjct: 258 HSLALAEDLNLVCVADRENGRIQCFDLDGTFKFIIQHQQ---FGPRLFAI 398

 Score = 30.4 bits (67), Expect = 2.5,   Method: Compositional matrix adjust.
 Identities = 36/117 (30%), Positives = 48/117 (41%), Gaps = 13/117 (11%)
 Frame = +3

Query: 500 IVVADSNNQCIQVFSNEGQFKF-----RFGVRGRSPGQLQRPTGVAVDTNGDIIVADYDN 554
           + VAD  N  IQ F  +G FKF     +FG R  +     R  G+    NG     D + 
Sbjct: 291 VCVADRENGRIQCFDLDGTFKFIIQHQQFGPRLFAIEYCPRHGGLLYAVNGPTF--DGET 464

Query: 555 RWVSIFSPEGKFKTKI-------GAGRLMGPKGVAVDRNGHIIVV-DNKSCCVFTFQ 603
             V  F+   +  T +       G G L  P  VAVD  GH + V +     V+ FQ
Sbjct: 465 STVQGFTIRVRDNTLLETWTLPTGQG-LQNPHDVAVDVEGHAVYVGELNPSSVWKFQ 632
>20704
          Length = 874

 Score = 38.1 bits (87), Expect = 0.011,   Method: Compositional matrix adjust.
 Identities = 26/89 (29%), Positives = 38/89 (42%), Gaps = 7/89 (7%)
 Frame = -1

Query: 16  DKQFLVCSICLDRYRCPKVLPCLHTFCERCLQNYIPPQSLTLSCPVCRQTSILPEQG--- 72
           DK    C +C + Y   K+LPC HT C +C+  ++        CP+CR   + P      
Sbjct: 352 DKSEFECPVCHEDYDQHKILPCKHTACHKCILTWLQKGGRNRGCPLCRVPILSPSTAHHD 173

Query: 73  ----VSALQNNFFISSLMEAMQQAPEGAH 97
               V AL     +   +E  QQ  +G H
Sbjct: 172 LKLLVDALPTGLVVEIQIEN-QQLLKGPH 89
>20092
          Length = 467

 Score = 37.7 bits (86), Expect = 0.015,   Method: Composition-based stats.
 Identities = 25/70 (35%), Positives = 36/70 (51%), Gaps = 1/70 (1%)
 Frame = +1

Query: 516 EGQFKFRFGVRGRSPGQLQRPTGVAVDTNGDIIVADYDNRWVSIFSPEGKFKTKIGAG-R 574
           +G F+ R     +  G    PTGV V++ GD+IVAD  N  V I +  G+   K GA  +
Sbjct: 250 DGLFEIRAKCVEKIRGDFDHPTGVCVNSKGDVIVADTANHVVKICN-NGRVIKKFGADLK 426

Query: 575 LMGPKGVAVD 584
           +  P  V V+
Sbjct: 427 MWRPSAVVVN 456

 Score = 34.3 bits (77), Expect = 0.18,   Method: Composition-based stats.
 Identities = 17/47 (36%), Positives = 27/47 (57%)
 Frame = +1

Query: 649 YSADGEFLFKFGSHGEGNGQFNAPTGVAVDSNGNIIVADWGNSRIQV 695
           +  DG F  +     +  G F+ PTGV V+S G++IVAD  N  +++
Sbjct: 241 HVGDGLFEIRAKCVEKIRGDFDHPTGVCVNSKGDVIVADTANHVVKI 381

 Score = 32.0 bits (71), Expect = 0.96,   Method: Composition-based stats.
 Identities = 18/60 (30%), Positives = 34/60 (56%)
 Frame = +1

Query: 483 KGEFTNLQGVSAASSGRIVVADSNNQCIQVFSNEGQFKFRFGVRGRSPGQLQRPTGVAVD 542
           +G+F +  GV   S G ++VAD+ N  +++  N G+   +FG    +  ++ RP+ V V+
Sbjct: 292 RGDFDHPTGVCVNSKGDVIVADTANHVVKI-CNNGRVIKKFG----ADLKMWRPSAVVVN 456
>10203
          Length = 2103

 Score = 35.4 bits (80), Expect = 0.081,   Method: Compositional matrix adjust.
 Identities = 15/44 (34%), Positives = 24/44 (54%)
 Frame = -2

Query: 22   CSICLDRYRCPKVLPCLHTFCERCLQNYIPPQSLTLSCPVCRQT 65
            C+IC +     + LPC H F   CL++++   +   SCP CR +
Sbjct: 1109 CAICWEGMEAARKLPCGHLFHNSCLRSWLEQDT---SCPTCRMS 987
>06811
          Length = 674

 Score = 34.3 bits (77), Expect = 0.19,   Method: Composition-based stats.
 Identities = 21/82 (25%), Positives = 41/82 (50%)
 Frame = -2

Query: 171 GRLPQLSAAIALVGGISQQLQERKAEALAQISAAFEDLEQALQQRKQALVSDLESICGAK 230
           G +  L+AA   V    +QL+      L  I+ +F+D+   + +R+   +  +  I   K
Sbjct: 436 GAIKNLNAAYDAVSEELRQLELSVDRTLDGINRSFQDVIAVVDRRRHECLQWVRKIKEEK 257

Query: 231 QKVLQTQLDTLRQGQEHIGSSC 252
           + VL+ QLD ++  ++ + S C
Sbjct: 256 KNVLKEQLDLIQAEKDKVQSEC 191
>03240
          Length = 1683

 Score = 34.3 bits (77), Expect = 0.20,   Method: Compositional matrix adjust.
 Identities = 16/46 (34%), Positives = 21/46 (45%)
 Frame = -3

Query: 574 RLMGPKGVAVDRNGHIIVVDNKSCCVFTFQPNGKLVGRFGGRGATD 619
           R + P  + +DRNGHI + D   C  F +  N K   R G     D
Sbjct: 919 RDIKPDNILIDRNGHIKLTDFGLCTGFRWTHNSKYYQRDGTHARQD 782
>27368
          Length = 394

 Score = 33.9 bits (76), Expect = 0.23,   Method: Composition-based stats.
 Identities = 16/45 (35%), Positives = 24/45 (53%)
 Frame = +1

Query: 20 LVCSICLDRYRCPKVLPCLHTFCERCLQNYIPPQSLTLSCPVCRQ 64
          L+C +C      P    C HTFC  CL++++  Q+L   CP  +Q
Sbjct: 4  LLCQLCHQPLVDPLETKCGHTFCTSCLKSHLAVQAL---CPEDKQ 129
>14716
          Length = 481

 Score = 33.1 bits (74), Expect = 0.36,   Method: Compositional matrix adjust.
 Identities = 20/59 (33%), Positives = 29/59 (49%)
 Frame = +2

Query: 20  LVCSICLDRYRCPKVLPCLHTFCERCLQNYIPPQSLTLSCPVCRQTSILPEQGVSALQN 78
           L CS+CL   R   +  C H FC  C+  +   ++    CP+CR+    P   + ALQN
Sbjct: 146 LKCSLCLGPRRRTTLTVCGHLFCWDCIHQWCQEKA---ECPLCREQ--FPPHRLVALQN 307
>12312
          Length = 477

 Score = 33.1 bits (74), Expect = 0.44,   Method: Composition-based stats.
 Identities = 21/73 (28%), Positives = 34/73 (46%), Gaps = 2/73 (2%)
 Frame = -3

Query: 15  MDKQFLVCSICLDR--YRCPKVLPCLHTFCERCLQNYIPPQSLTLSCPVCRQTSILPEQG 72
           MD Q++   +C+D   Y C  V  C+H     C+ + +P  S+T    + R   I   + 
Sbjct: 223 MDSQYVFVYMCVDVCVYLCVCVHLCVHVCMY*CVNSLLPNCSMTFKPNIGRGICIKHYEV 44

Query: 73  VSALQNNFFISSL 85
            SA   +FF+S  
Sbjct: 43  TSATVLSFFLSKF 5
>18689
          Length = 723

 Score = 32.7 bits (73), Expect = 0.51,   Method: Composition-based stats.
 Identities = 13/22 (59%), Positives = 15/22 (68%)
 Frame = +2

Query: 25  CLDRYRCPKVLPCLHTFCERCL 46
           CL +YR    LPCLHT CE C+
Sbjct: 104 CLTKYR--NFLPCLHTMCEDCI 163
>17930
          Length = 798

 Score = 32.3 bits (72), Expect = 0.64,   Method: Compositional matrix adjust.
 Identities = 14/41 (34%), Positives = 20/41 (48%), Gaps = 1/41 (2%)
 Frame = -2

Query: 6   DSPGPEVQPMDKQF-LVCSICLDRYRCPKVLPCLHTFCERC 45
           D+   E+   D+ F   C IC   +  P V  C H +CE+C
Sbjct: 149 DNQNYEISSEDEDFPFKCFICRKSFVNPVVTKCKHYYCEKC 27
>23915
          Length = 1006

 Score = 31.6 bits (70), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 30/98 (30%), Positives = 42/98 (42%), Gaps = 9/98 (9%)
 Frame = +1

Query: 507 NQCIQVFS-----NEGQFKFRFGVRGRSPGQLQRPTGVAVDTNGDIIVADYDNRWVSIFS 561
           NQ I +FS      +   KF F            P  VAV  NGDIIV+D   R++ IFS
Sbjct: 136 NQSIHLFSFKILKKDAANKFLF----------LSPMDVAVAGNGDIIVSDA-GRFIQIFS 282

Query: 562 PE----GKFKTKIGAGRLMGPKGVAVDRNGHIIVVDNK 595
            +      +++ +    L    GV  D  G + + D K
Sbjct: 283 SDFVLKKSYQSPLADSELW---GVCTDPGGSVYIADWK 387
>29288
          Length = 421

 Score = 31.6 bits (70), Expect = 1.3,   Method: Composition-based stats.
 Identities = 14/43 (32%), Positives = 25/43 (58%)
 Frame = -1

Query: 32  PKVLPCLHTFCERCLQNYIPPQSLTLSCPVCRQTSILPEQGVS 74
           P +L C H+FC+ CL+     +  T+ CP C++ + L  + V+
Sbjct: 400 PMLLRCGHSFCKPCLRKCETTED-TIQCPTCQKPTRLSLKTVN 275
>07293
          Length = 3312

 Score = 31.2 bits (69), Expect = 1.4,   Method: Compositional matrix adjust.
 Identities = 15/28 (53%), Positives = 20/28 (71%)
 Frame = -3

Query: 151  LRDVVEQHKAALQRQLEAVRGRLPQLSA 178
            LR  V+QH AALQ Q + ++G + QLSA
Sbjct: 3181 LRQQVDQHDAALQSQFDHLQGAVQQLSA 3098
>15938
          Length = 752

 Score = 31.2 bits (69), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 19/64 (29%), Positives = 28/64 (43%), Gaps = 1/64 (1%)
 Frame = +1

Query: 4   REDSPGPEVQPMDKQF-LVCSICLDRYRCPKVLPCLHTFCERCLQNYIPPQSLTLSCPVC 62
           + D+   E+   D+ F   C IC   +  P V  C H +CE+C    +     T  C VC
Sbjct: 175 QNDNQNYEISSEDEDFPFKCFICRKSFVNPVVTKCKHYYCEKCA---LAQYKKTQRCFVC 345

Query: 63  RQTS 66
            Q +
Sbjct: 346 GQQT 357
>27237
          Length = 704

 Score = 31.2 bits (69), Expect = 1.7,   Method: Compositional matrix adjust.
 Identities = 23/86 (26%), Positives = 42/86 (48%), Gaps = 3/86 (3%)
 Frame = -1

Query: 115 CPNHEGKTMEFYCEACETAMCGECRAGEHREHGTVLLRDV---VEQHKAALQRQLEAVRG 171
           C +H  ++ + YC A   ++C  C A  HR    V  RD+    E+ +A L++  + +  
Sbjct: 425 CASHPDESCQLYCTAHSVSICHLCAASVHRNCSEV--RDIHGRAEEARAELKKMADKLSA 252

Query: 172 RLPQLSAAIALVGGISQQLQERKAEA 197
              Q++  I  +    Q++ E+K EA
Sbjct: 251 GESQINERINKIDDSLQKM-EKKGEA 177
>33593
          Length = 559

 Score = 31.2 bits (69), Expect = 1.7,   Method: Composition-based stats.
 Identities = 16/60 (26%), Positives = 27/60 (45%), Gaps = 5/60 (8%)
 Frame = -3

Query: 10  PEVQPMDKQ-----FLVCSICLDRYRCPKVLPCLHTFCERCLQNYIPPQSLTLSCPVCRQ 64
           P +Q   +Q      + C +C D    P  + C+H FC  C+ + +     + +CP C Q
Sbjct: 431 PSIQTXCQQRSRADLMECVVCGDWPIHPHHIGCIHXFCYFCIASNLKADP-SYTCPACGQ 255
>31249
          Length = 543

 Score = 30.8 bits (68), Expect = 1.9,   Method: Composition-based stats.
 Identities = 13/43 (30%), Positives = 21/43 (48%)
 Frame = -3

Query: 21  VCSICLDRYRCPKVLPCLHTFCERCLQNYIPPQSLTLSCPVCR 63
           VC++CL      +V  C H F   C++  +   S    CP+C+
Sbjct: 343 VCAVCLGSMGXARVTRCHHLFHAXCIRQLLEVSS---HCPLCK 224
>08613
          Length = 973

 Score = 30.0 bits (66), Expect = 3.7,   Method: Composition-based stats.
 Identities = 13/35 (37%), Positives = 18/35 (51%), Gaps = 1/35 (2%)
 Frame = +2

Query: 31 CPKVL-PCLHTFCERCLQNYIPPQSLTLSCPVCRQ 64
          CP V   C H F   C+  ++  Q +   CP+CRQ
Sbjct: 8  CPLVWGQCSHCFHIHCIVKWLNSQQVHQPCPMCRQ 112
>14417
          Length = 1383

 Score = 29.3 bits (64), Expect = 5.7,   Method: Compositional matrix adjust.
 Identities = 19/60 (31%), Positives = 27/60 (45%)
 Frame = +2

Query: 10  PEVQPMDKQFLVCSICLDRYRCPKVLPCLHTFCERCLQNYIPPQSLTLSCPVCRQTSILP 69
           P+V+ M     V S+   +   PK LPC H FC  CL   +        CP C++   +P
Sbjct: 467 PQVKLMSLTDAVPSVWKKKSHNPK-LPCGHRFCASCLDRAM---INNPRCPKCQRLYGIP 634
>07523
          Length = 1299

 Score = 29.3 bits (64), Expect = 6.7,   Method: Compositional matrix adjust.
 Identities = 15/43 (34%), Positives = 21/43 (48%), Gaps = 1/43 (2%)
 Frame = -1

Query: 22  CSICLDRYRCPKVLPCLH-TFCERCLQNYIPPQSLTLSCPVCR 63
           C IC+   R   +LPC H   C  C ++     S+   CP+CR
Sbjct: 456 CVICMSDMRDTLILPCRHLCLCSACAESLRYQASM---CPICR 337
>16700
          Length = 1234

 Score = 28.9 bits (63), Expect = 7.5,   Method: Compositional matrix adjust.
 Identities = 10/17 (58%), Positives = 12/17 (70%)
 Frame = -1

Query: 27  DRYRCPKVLPCLHTFCE 43
           DR+ CP  LPCL  FC+
Sbjct: 361 DRFTCPPTLPCLLIFCQ 311
>09947
          Length = 860

 Score = 28.9 bits (63), Expect = 7.6,   Method: Compositional matrix adjust.
 Identities = 19/55 (34%), Positives = 27/55 (49%)
 Frame = -1

Query: 507 NQCIQVFSNEGQFKFRFGVRGRSPGQLQRPTGVAVDTNGDIIVADYDNRWVSIFS 561
           NQ ++V   E    F +        Q QR   VAVD NGD+ V  Y+ R  ++F+
Sbjct: 617 NQTLEV---EDSLTFTW--------QDQRGESVAVDPNGDVYVMSYEERGDAMFA 486
>27286
          Length = 454

 Score = 28.9 bits (63), Expect = 8.5,   Method: Compositional matrix adjust.
 Identities = 18/40 (45%), Positives = 21/40 (52%), Gaps = 1/40 (2%)
 Frame = +3

Query: 109 AGRPLSCPNHEGKTMEFYCEACETAMC-GECRAGEHREHG 147
            G P   P H GKT   + +AC+TA C   CR G H  HG
Sbjct: 333 CGTPARAPEHSGKT---F*QACQTAACDSSCRRGCHVGHG 443
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|14010849|ref|NP_109631.1| tripartite motif protein 2
[Mus musculus]
         (744 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

03572                                                                 342   2e-94
03602                                                                 105   7e-23
11956                                                                 100   4e-21
29117                                                                  74   1e-13
20109                                                                  66   5e-11
07490                                                                  57   3e-08
32269                                                                  53   4e-07
17351                                                                  51   1e-06
27774                                                                  46   6e-05
18021                                                                  41   8e-05
13043                                                                  45   1e-04
19277                                                                  44   2e-04
14625                                                                  43   4e-04
20514                                                                  42   8e-04
33436                                                                  42   8e-04
20704                                                                  42   0.001
16231                                                                  40   0.004
20092                                                                  40   0.004
27230                                                                  39   0.008
18540                                                                  39   0.011
14716                                                                  38   0.012
10203                                                                  37   0.020
29755                                                                  37   0.024
27368                                                                  36   0.053
29288                                                                  35   0.14 
33593                                                                  34   0.21 
18689                                                                  34   0.24 
15938                                                                  34   0.24 
03240                                                                  33   0.37 
17930                                                                  33   0.57 
14417                                                                  32   0.67 
21436                                                                  32   1.1  
31249                                                                  32   1.3  
00178                                                                  31   1.7  
07523                                                                  31   1.7  
27069                                                                  30   2.9  
26463                                                                  30   3.4  
23915                                                                  29   6.0  
>03572
          Length = 776

 Score =  342 bits (878), Expect = 2e-94,   Method: Compositional matrix adjust.
 Identities = 157/218 (72%), Positives = 188/218 (86%)
 Frame = -1

Query: 527 GRSPGQLQRPTGVAVHPSGDIIIADYDNKWVSIFSNDGKFKTKIGSGKLMGPKGVSVDRN 586
           GR  G++QRPTGVAV  +G+ ++ADYDNKWVS+F+ DGK+ +KIG+G+L GPKGV+VD N
Sbjct: 770 GRVAGKIQRPTGVAVTLNGNYLVADYDNKWVSVFAPDGKYISKIGTGRLQGPKGVAVDNN 591

Query: 587 GHIIVVDNKACCVFIFQPNGKIVTRFGSRGNGDRQFAGPHFAAVNSNNEIIITDFHNHSV 646
           GHIIVVDNKA  V +FQ NGK++ +FGSRGN D QFAGPH+AA+  NN+II++DFHNHSV
Sbjct: 590 GHIIVVDNKASSVLVFQNNGKLLHKFGSRGNEDYQFAGPHYAAITKNNDIIVSDFHNHSV 411

Query: 647 KVFNQEGEFMLKFGSNGEGNGQFNAPTGVAVDSNGNIIVADWGNSRIQVFDGSGSFLSYI 706
           KVF  +G F+  FGS GEGNGQFNAPTGVAVD NG+I+VADWGNSRIQVFD +GSFLSY+
Sbjct: 410 KVFGSDGSFLFCFGSMGEGNGQFNAPTGVAVDPNGHILVADWGNSRIQVFDANGSFLSYV 231

Query: 707 NTSADPLYGPQGLALTSDGHVVVADSGNHCFKVYRYLQ 744
           NTSA+PLYGPQGL +TSDG VVVADSGNHC K Y+YLQ
Sbjct: 230 NTSAEPLYGPQGLGVTSDGQVVVADSGNHCIKFYKYLQ 117

 Score =  120 bits (302), Expect = 2e-27,   Method: Compositional matrix adjust.
 Identities = 77/224 (34%), Positives = 118/224 (52%), Gaps = 5/224 (2%)
 Frame = -1

Query: 478 TKGRNKGEFTNLQGVAASTSGKILIADSNNQCVQIFSNDGQFKSRFGIRGRSPGQLQRPT 537
           + GR  G+     GVA + +G  L+AD +N+ V +F+ DG++ S+ G      G+LQ P 
Sbjct: 776 SAGRVAGKIQRPTGVAVTLNGNYLVADYDNKWVSVFAPDGKYISKIGT-----GRLQGPK 612

Query: 538 GVAVHPSGDIIIADYDNKWVSIFSNDGKFKTKIGSG-----KLMGPKGVSVDRNGHIIVV 592
           GVAV  +G II+ D     V +F N+GK   K GS      +  GP   ++ +N  IIV 
Sbjct: 611 GVAVDNNGHIIVVDNKASSVLVFQNNGKLLHKFGSRGNEDYQFAGPHYAAITKNNDIIVS 432

Query: 593 DNKACCVFIFQPNGKIVTRFGSRGNGDRQFAGPHFAAVNSNNEIIITDFHNHSVKVFNQE 652
           D     V +F  +G  +  FGS G G+ QF  P   AV+ N  I++ D+ N  ++VF+  
Sbjct: 431 DFHNHSVKVFGSDGSFLFCFGSMGEGNGQFNAPTGVAVDPNGHILVADWGNSRIQVFDAN 252

Query: 653 GEFMLKFGSNGEGNGQFNAPTGVAVDSNGNIIVADWGNSRIQVF 696
           G F+    ++ E       P G+ V S+G ++VAD GN  I+ +
Sbjct: 251 GSFLSYVNTSAE---PLYGPQGLGVTSDGQVVVADSGNHCIKFY 129

 Score = 94.7 bits (234), Expect = 1e-19,   Method: Compositional matrix adjust.
 Identities = 61/192 (31%), Positives = 95/192 (49%), Gaps = 5/192 (2%)
 Frame = -1

Query: 473 IFRVGTKGRNKGEFTNLQGVAASTSGKILIADSNNQCVQIFSNDGQFKSRFGIRGRSPGQ 532
           I ++GT GR +G     +GVA   +G I++ D+    V +F N+G+   +FG RG    Q
Sbjct: 650 ISKIGT-GRLQGP----KGVAVDNNGHIIVVDNKASSVLVFQNNGKLLHKFGSRGNEDYQ 486

Query: 533 LQRPTGVAVHPSGDIIIADYDNKWVSIFSNDGKFKTKIGS-----GKLMGPKGVSVDRNG 587
              P   A+  + DII++D+ N  V +F +DG F    GS     G+   P GV+VD NG
Sbjct: 485 FAGPHYAAITKNNDIIVSDFHNHSVKVFGSDGSFLFCFGSMGEGNGQFNAPTGVAVDPNG 306

Query: 588 HIIVVDNKACCVFIFQPNGKIVTRFGSRGNGDRQFAGPHFAAVNSNNEIIITDFHNHSVK 647
           HI+V D     + +F  NG  ++   +         GP    V S+ ++++ D  NH +K
Sbjct: 305 HILVADWGNSRIQVFDANGSFLSYVNTSA---EPLYGPQGLGVTSDGQVVVADSGNHCIK 135

Query: 648 VFNQEGEFMLKF 659
            +     F L F
Sbjct: 134 FYKYLQ*FHLPF 99

 Score = 86.3 bits (212), Expect = 4e-17,   Method: Compositional matrix adjust.
 Identities = 42/134 (31%), Positives = 75/134 (55%), Gaps = 2/134 (1%)
 Frame = -1

Query: 472 LIFRVGTKGRNKGEFTNLQGVAASTSGKILIADSNNQCVQIFSNDGQFKSRFGIRGRSPG 531
           L+ + G++G    +F      A + +  I+++D +N  V++F +DG F   FG  G   G
Sbjct: 527 LLHKFGSRGNEDYQFAGPHYAAITKNNDIIVSDFHNHSVKVFGSDGSFLFCFGSMGEGNG 348

Query: 532 QLQRPTGVAVHPSGDIIIADYDNKWVSIFSNDGKFKTKIGSGK--LMGPKGVSVDRNGHI 589
           Q   PTGVAV P+G I++AD+ N  + +F  +G F + + +    L GP+G+ V  +G +
Sbjct: 347 QFNAPTGVAVDPNGHILVADWGNSRIQVFDANGSFLSYVNTSAEPLYGPQGLGVTSDGQV 168

Query: 590 IVVDNKACCVFIFQ 603
           +V D+   C+  ++
Sbjct: 167 VVADSGNHCIKFYK 126

 Score = 56.2 bits (134), Expect = 5e-08,   Method: Compositional matrix adjust.
 Identities = 31/72 (43%), Positives = 45/72 (62%)
 Frame = -1

Query: 661 SNGEGNGQFNAPTGVAVDSNGNIIVADWGNSRIQVFDGSGSFLSYINTSADPLYGPQGLA 720
           S G   G+   PTGVAV  NGN +VAD+ N  + VF   G ++S I T    L GP+G+A
Sbjct: 776 SAGRVAGKIQRPTGVAVTLNGNYLVADYDNKWVSVFAPDGKYISKIGTGR--LQGPKGVA 603

Query: 721 LTSDGHVVVADS 732
           + ++GH++V D+
Sbjct: 602 VDNNGHIIVVDN 567

 Score = 48.9 bits (115), Expect = 8e-06,   Method: Compositional matrix adjust.
 Identities = 28/92 (30%), Positives = 43/92 (46%)
 Frame = -1

Query: 469 EDDLIFRVGTKGRNKGEFTNLQGVAASTSGKILIADSNNQCVQIFSNDGQFKSRFGIRGR 528
           +   +F  G+ G   G+F    GVA   +G IL+AD  N  +Q+F  +G F S       
Sbjct: 395 DGSFLFCFGSMGEGNGQFNAPTGVAVDPNGHILVADWGNSRIQVFDANGSFLSYV---NT 225

Query: 529 SPGQLQRPTGVAVHPSGDIIIADYDNKWVSIF 560
           S   L  P G+ V   G +++AD  N  +  +
Sbjct: 224 SAEPLYGPQGLGVTSDGQVVVADSGNHCIKFY 129
>03602
          Length = 1190

 Score =  105 bits (262), Expect = 7e-23,   Method: Compositional matrix adjust.
 Identities = 59/155 (38%), Positives = 85/155 (54%), Gaps = 3/155 (1%)
 Frame = -3

Query: 578 PKGVSVDRNGHIIVVDNKACCVFIFQPNGKIVTRFGSRGNGDRQFAGPHFAAVNSNNEII 637
           P G++   NG  ++   +   VFIF    K  ++FG +G GD  F  P F   NS N+I+
Sbjct: 969 PHGITALANGGAVITSKQNQNVFIFTDQLKYSSKFGRKGTGDGYFHSPQFVTTNSRNQIV 790

Query: 638 ITDFHNHSVKVFNQEGEFMLKFGSNGEGNGQFNAPTGVAVDSNGNIIVADWGNSRIQVFD 697
           +TD  N +V+VFN  GE   +FG +G   G+F  P GVA DS+ N+ VAD GN R+Q F+
Sbjct: 789 VTDDMNDNVQVFNWLGELKFRFGRSGSKPGEFVRPMGVATDSDDNMYVADSGNCRVQKFN 610

Query: 698 GSGSFLSYINTSADPL---YGPQGLALTSDGHVVV 729
             G + + + +    L     P  +A+TS G V V
Sbjct: 609 CKGVYQNLVVSDTHCLGQDVXPVNVAVTSAGDVAV 505

 Score = 70.9 bits (172), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 60/206 (29%), Positives = 97/206 (47%), Gaps = 10/206 (4%)
 Frame = -3

Query: 548  IIADYDNKWVSIFSNDGKFKTKIGSGKLMGPKGVSVDRNGHIIVVDNKACCVF-IFQPNG 606
            +++D  +  + +F + G+ KT I     +  K V+V R   I+VV NK      I+   G
Sbjct: 1185 VVSDSGSGRIFVFYSHGEVKTTITCDCRI--KDVAVSRRNEILVVVNKPSVALQIYTVTG 1012

Query: 607  KIVTRFGSRGNGDRQFAGPHFAAVNSNNEIIITDFHNHSVKVFNQEGEFMLKFGSNGEGN 666
             ++   G     +     PH     +N   +IT   N +V +F  + ++  KFG  G G+
Sbjct: 1011 HLLGEHGKFITHED----PHGITALANGGAVITSKQNQNVFIFTDQLKYSSKFGRKGTGD 844

Query: 667  GQFNAPTGVAVDSNGNIIVADWGNSRIQVFDGSGSF-LSYINTSADP--LYGPQGLALTS 723
            G F++P  V  +S   I+V D  N  +QVF+  G     +  + + P     P G+A  S
Sbjct: 843  GYFHSPQFVTTNSRNQIVVTDDMNDNVQVFNWLGELKFRFGRSGSKPGEFVRPMGVATDS 664

Query: 724  DGHVVVADSGN------HCFKVYRYL 743
            D ++ VADSGN      +C  VY+ L
Sbjct: 663  DDNMYVADSGNCRVQKFNCKGVYQNL 586

 Score = 61.6 bits (148), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 39/123 (31%), Positives = 62/123 (50%), Gaps = 5/123 (4%)
 Frame = -3

Query: 475 RVGTKGRNKGEFTNLQGVAASTSGKILIADSNNQCVQIFSNDGQFKSRFGIRGRSPGQLQ 534
           + G KG   G F + Q V  ++  +I++ D  N  VQ+F+  G+ K RFG  G  PG+  
Sbjct: 870 KFGRKGTGDGYFHSPQFVTTNSRNQIVVTDDMNDNVQVFNWLGELKFRFGRSGSKPGEFV 691

Query: 535 RPTGVAVHPSGDIIIADYDNKWVSIFSNDGKFKTKIGS-----GKLMGPKGVSVDRNGHI 589
           RP GVA     ++ +AD  N  V  F+  G ++  + S     G+ + P  V+V   G +
Sbjct: 690 RPMGVATDSDDNMYVADSGNCRVQKFNCKGVYQNLVVSDTHCLGQDVXPVNVAVTSAGDV 511

Query: 590 IVV 592
            V+
Sbjct: 510 AVL 502

 Score = 43.9 bits (102), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 27/79 (34%), Positives = 38/79 (48%)
 Frame = -3

Query: 471 DLIFRVGTKGRNKGEFTNLQGVAASTSGKILIADSNNQCVQIFSNDGQFKSRFGIRGRSP 530
           +L FR G  G   GEF    GVA  +   + +ADS N  VQ F+  G +++         
Sbjct: 741 ELKFRFGRSGSKPGEFVRPMGVATDSDDNMYVADSGNCRVQKFNCKGVYQNLVVSDTHCL 562

Query: 531 GQLQRPTGVAVHPSGDIII 549
           GQ   P  VAV  +GD+ +
Sbjct: 561 GQDVXPVNVAVTSAGDVAV 505
>11956
          Length = 501

 Score = 99.8 bits (247), Expect = 4e-21,   Method: Composition-based stats.
 Identities = 52/131 (39%), Positives = 73/131 (55%)
 Frame = -3

Query: 573 GKLMGPKGVSVDRNGHIIVVDNKACCVFIFQPNGKIVTRFGSRGNGDRQFAGPHFAAVNS 632
           G    P+G++V  +  I+V D+    V +F  NG  V  FG  GNG+ +F      AVN 
Sbjct: 490 GSFTWPRGLAVGPDNSIVVADSSNHRVQVFDSNGIFVKEFGEYGNGEGEFDCLAGVAVNR 311

Query: 633 NNEIIITDFHNHSVKVFNQEGEFMLKFGSNGEGNGQFNAPTGVAVDSNGNIIVADWGNSR 692
             + II D +NH ++V + +G F+  FGS G  +G+FN P GV  D+ G I V D  N R
Sbjct: 310 IGQYIIADRYNHRIQVLDPQGRFLRAFGSQGIADGKFNYPWGVTTDALGFIYVCDKENHR 131

Query: 693 IQVFDGSGSFL 703
           +QVF   GSF+
Sbjct: 130 VQVFQSDGSFV 98

 Score = 94.4 bits (233), Expect = 2e-19,   Method: Composition-based stats.
 Identities = 56/152 (36%), Positives = 78/152 (51%), Gaps = 5/152 (3%)
 Frame = -3

Query: 484 GEFTNLQGVAASTSGKILIADSNNQCVQIFSNDGQFKSRFGIRGRSPGQLQRPTGVAVHP 543
           G FT  +G+A      I++ADS+N  VQ+F ++G F   FG  G   G+     GVAV+ 
Sbjct: 490 GSFTWPRGLAVGPDNSIVVADSSNHRVQVFDSNGIFVKEFGEYGNGEGEFDCLAGVAVNR 311

Query: 544 SGDIIIADYDNKWVSIFSNDGKFKTKIGS-----GKLMGPKGVSVDRNGHIIVVDNKACC 598
            G  IIAD  N  + +    G+F    GS     GK   P GV+ D  G I V D +   
Sbjct: 310 IGQYIIADRYNHRIQVLDPQGRFLRAFGSQGIADGKFNYPWGVTTDALGFIYVCDKENHR 131

Query: 599 VFIFQPNGKIVTRFGSRGNGDRQFAGPHFAAV 630
           V +FQ +G  V +FGS G G+ Q   PH++ +
Sbjct: 130 VQVFQSDGSFVGKFGSCGRGEGQLEHPHYSRI 35

 Score = 92.4 bits (228), Expect = 6e-19,   Method: Composition-based stats.
 Identities = 51/148 (34%), Positives = 74/148 (50%), Gaps = 5/148 (3%)
 Frame = -3

Query: 530 PGQLQRPTGVAVHPSGDIIIADYDNKWVSIFSNDGKFKTKIGS-----GKLMGPKGVSVD 584
           PG    P G+AV P   I++AD  N  V +F ++G F  + G      G+     GV+V+
Sbjct: 493 PGSFTWPRGLAVGPDNSIVVADSSNHRVQVFDSNGIFVKEFGEYGNGEGEFDCLAGVAVN 314

Query: 585 RNGHIIVVDNKACCVFIFQPNGKIVTRFGSRGNGDRQFAGPHFAAVNSNNEIIITDFHNH 644
           R G  I+ D     + +  P G+ +  FGS+G  D +F  P     ++   I + D  NH
Sbjct: 313 RIGQYIIADRYNHRIQVLDPQGRFLRAFGSQGIADGKFNYPWGVTTDALGFIYVCDKENH 134

Query: 645 SVKVFNQEGEFMLKFGSNGEGNGQFNAP 672
            V+VF  +G F+ KFGS G G GQ   P
Sbjct: 133 RVQVFQSDGSFVGKFGSCGRGEGQLEHP 50

 Score = 68.6 bits (166), Expect = 8e-12,   Method: Composition-based stats.
 Identities = 43/132 (32%), Positives = 63/132 (47%), Gaps = 5/132 (3%)
 Frame = -3

Query: 477 GTKGRNKGEFTNLQGVAASTSGKILIADSNNQCVQIFSNDGQFKSRFGIRGRSPGQLQRP 536
           G  G  +GEF  L GVA +  G+ +IAD  N  +Q+    G+F   FG +G + G+   P
Sbjct: 370 GEYGNGEGEFDCLAGVAVNRIGQYIIADRYNHRIQVLDPQGRFLRAFGSQGIADGKFNYP 191

Query: 537 TGVAVHPSGDIIIADYDNKWVSIFSNDGKFKTKIGS-----GKLMGPKGVSVDRNGHIIV 591
            GV     G I + D +N  V +F +DG F  K GS     G+L  P         H   
Sbjct: 190 WGVTTDALGFIYVCDKENHRVQVFQSDGSFVGKFGSCGRGEGQLEHP---------HYSR 38

Query: 592 VDNKACCVFIFQ 603
           ++ ++C  F F+
Sbjct: 37  IEYESCYCFRFE 2

 Score = 31.6 bits (70), Expect = 1.4,   Method: Composition-based stats.
 Identities = 13/25 (52%), Positives = 18/25 (72%)
 Frame = -3

Query: 716 PQGLALTSDGHVVVADSGNHCFKVY 740
           P+GLA+  D  +VVADS NH  +V+
Sbjct: 475 PRGLAVGPDNSIVVADSSNHRVQVF 401
>29117
          Length = 320

 Score = 74.3 bits (181), Expect = 1e-13,   Method: Composition-based stats.
 Identities = 31/82 (37%), Positives = 47/82 (57%), Gaps = 3/82 (3%)
 Frame = +1

Query: 13  VRQIDKQFLICSICLERYKNPKVLPCLHTFCERCLQNYIPAHSL---TLSCPVCRQTSIL 69
           V  +   FL C +CL+ +  PK+LPC HTFC  CL+ Y+  ++       CP+C++T I+
Sbjct: 46  VEGLKDDFLTCPLCLQLFTEPKILPCQHTFCSHCLRKYLDHNTFLQWQCVCPLCKKTCIV 225

Query: 70  PEKGVAALQNNFFITNLMDVLQ 91
            E  V  L NNF I  L+  ++
Sbjct: 226 REGDVTKLPNNFLIVGLLHFVK 291
>20109
          Length = 418

 Score = 65.9 bits (159), Expect = 5e-11,   Method: Composition-based stats.
 Identities = 26/67 (38%), Positives = 41/67 (61%), Gaps = 1/67 (1%)
 Frame = -1

Query: 18  KQFLICSICLERYKNPKVLPCLHTFCERCLQNYIP-AHSLTLSCPVCRQTSILPEKGVAA 76
           K+ + C++C E +++P+ LPC HTFC +CL +    + S T  CPVCR    +P   V+ 
Sbjct: 346 KERVTCTVCFEVFRDPRFLPCHHTFCLQCLADLASRSPSSTFPCPVCRHHVTVPHGSVST 167

Query: 77  LQNNFFI 83
            Q NF++
Sbjct: 166 FQTNFYL 146
>07490
          Length = 1665

 Score = 57.0 bits (136), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 64/245 (26%), Positives = 98/245 (40%), Gaps = 51/245 (20%)
 Frame = -2

Query: 30   YKNPKVLPCLHTFCERCLQNYIPAHSLTLSCPVCRQTSILPEKGVAALQNNFFITNLMDV 89
            +  PK+LPC H FC+ CL  ++ +     +CP CR   I P K V          +L+D 
Sbjct: 1661 FVEPKLLPCGHHFCKACLLRWVESQGWRAACPFCRALIISPTKCV---------DSLVDG 1509

Query: 90   LQRTPGSNGEDSSILETVTAVAAGK-PLSCPNHDGNVMEF-YCQSCETAMCRECTE---- 143
            ++  P ++G    + E V A    + P  C   DG+V    YC  CE  MC  C +    
Sbjct: 1508 VESLPTNHG----LEELVKARQVVRSPNVCSRCDGSVEAVSYCIQCEAKMCPGCQDTHDQ 1341

Query: 144  -------------------GEHA----EHPTVPLKDVVEQHK--ASLQVQLD-------- 170
                               G+H     +HP  P       H+  A  Q   D        
Sbjct: 1340 TTXGHPVEAVRTLTEAKLAGKHVVKCEKHPDRPANYYCRSHQTLACDQCAQDDHSCCSGY 1161

Query: 171  -AVNK-------RLPE-IDSALQFISEIIHQLTNQKASIVD---DIHSTFDELQKTLNVR 218
             A++K       RL E +D   Q  + + +Q+   K S  +   DI+  FD+L+  L  +
Sbjct: 1160 LAISKLGPLARSRLQETVDVMKQNAANLAYQIKLAKYSYRETERDINEAFDDLEDRLESQ 981

Query: 219  KSVLL 223
            + +LL
Sbjct: 980  RQLLL 966
>32269
          Length = 555

 Score = 53.1 bits (126), Expect = 4e-07,   Method: Compositional matrix adjust.
 Identities = 40/139 (28%), Positives = 60/139 (43%), Gaps = 2/139 (1%)
 Frame = -3

Query: 599 VFIFQPNGKIVTRFGSRGNGDRQFAGPHFAAVNSNNEIIITDFHNHSVKVFNQEGEFMLK 658
           VF+    G +V  F    +       P   AV SN E  + DF  H V VFN+EG F+ +
Sbjct: 520 VFVITEGGDLVKWF----DCSDYMREPSDIAV-SNKEYFVCDFKGHCVVVFNEEGSFVRR 356

Query: 659 FGSNGEGNGQFNAPTGVAVDSNGNIIVADWGNSR--IQVFDGSGSFLSYINTSADPLYGP 716
            G         N P G+ +   G++++ D   +R  + VF   GS           +   
Sbjct: 355 IGC----ENITNYPNGIDLSDAGDVLIGDSHGNRFHVAVFQRDGSLTGEFQCPYVKVSRC 188

Query: 717 QGLALTSDGHVVVADSGNH 735
            GL +TS+G++V     NH
Sbjct: 187 CGLKITSEGYIVTLAKNNH 131

 Score = 37.4 bits (85), Expect = 0.022,   Method: Compositional matrix adjust.
 Identities = 31/119 (26%), Positives = 51/119 (42%), Gaps = 2/119 (1%)
 Frame = -3

Query: 494 ASTSGKILIADSNNQCVQIFSNDGQFKSRFGIRGRSPGQLQRPTGVAVHPSGDIIIAD-Y 552
           A ++ +  + D    CV +F+ +G F  R G    +      P G+ +  +GD++I D +
Sbjct: 442 AVSNKEYFVCDFKGHCVVVFNEEGSFVRRIGCENIT----NYPNGIDLSDAGDVLIGDSH 275

Query: 553 DNKW-VSIFSNDGKFKTKIGSGKLMGPKGVSVDRNGHIIVVDNKACCVFIFQPNGKIVT 610
            N++ V++F  DG       +G+   P  V V R           CC       G IVT
Sbjct: 274 GNRFHVAVFQRDGSL-----TGEFQCPY-VKVSR-----------CCGLKITSEGYIVT 149
>17351
          Length = 654

 Score = 51.2 bits (121), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 28/92 (30%), Positives = 47/92 (51%)
 Frame = -1

Query: 330 ATGEGLRQTIIGQPMSVTITTKDKDGELCKTGNAYLTAELSTPDGSVADGEILDNKNGTY 389
           A G GL + ++G+P    + T++        G   L   +  P  S AD E  D K+G+ 
Sbjct: 432 AGGSGLERGVVGEPAEFNVWTRE-------AGGGSLAISVEGP--SKADIEFKDRKDGSC 280

Query: 390 EFLYTVQKEGDFTLSLRLYDQHIRGSPFKLKV 421
           +  Y V + G++ + L+  D+HI  SPFK+ +
Sbjct: 279 DVSYKVTEPGEYRVGLKFNDRHIPDSPFKVYI 184
>27774
          Length = 448

 Score = 45.8 bits (107), Expect = 6e-05,   Method: Compositional matrix adjust.
 Identities = 21/39 (53%), Positives = 27/39 (69%)
 Frame = -3

Query: 654 EFMLKFGSNGEGNGQFNAPTGVAVDSNGNIIVADWGNSR 692
           +F+ KFG  G  +GQF  P+GVA+DS   +IVAD  NSR
Sbjct: 119 QFVTKFGEYGNSHGQFTEPSGVAIDSENRLIVADTNNSR 3

 Score = 36.2 bits (82), Expect = 0.046,   Method: Compositional matrix adjust.
 Identities = 16/37 (43%), Positives = 23/37 (62%)
 Frame = -3

Query: 518 QFKSRFGIRGRSPGQLQRPTGVAVHPSGDIIIADYDN 554
           QF ++FG  G S GQ   P+GVA+     +I+AD +N
Sbjct: 119 QFVTKFGEYGNSHGQFTEPSGVAIDSENRLIVADTNN 9

 Score = 31.2 bits (69), Expect = 1.8,   Method: Compositional matrix adjust.
 Identities = 12/36 (33%), Positives = 22/36 (61%)
 Frame = -3

Query: 472 LIFRVGTKGRNKGEFTNLQGVAASTSGKILIADSNN 507
            + + G  G + G+FT   GVA  +  ++++AD+NN
Sbjct: 116 FVTKFGEYGNSHGQFTEPSGVAIDSENRLIVADTNN 9
>18021
          Length = 485

 Score = 41.2 bits (95), Expect(2) = 8e-05,   Method: Composition-based stats.
 Identities = 16/39 (41%), Positives = 24/39 (61%)
 Frame = +1

Query: 56  LTLSCPVCRQTSILPEKGVAALQNNFFITNLMDVLQRTP 94
           ++ +CP C++   +PEKGVAA Q NF+I    +    TP
Sbjct: 118 VSFACPTCKKMVAVPEKGVAAFQTNFYIVTEREQPPATP 234

 Score = 23.5 bits (49), Expect(2) = 8e-05,   Method: Composition-based stats.
 Identities = 12/37 (32%), Positives = 19/37 (51%)
 Frame = +3

Query: 128 FYCQSCETAMCRECTEGEHAEHPTVPLKDVVEQHKAS 164
           F C+ C+  MC+ C      +H T+  K  V  HK++
Sbjct: 285 FVCEKCQQRMCQPCRR----KHDTIINK--VANHKST 377
>13043
          Length = 1574

 Score = 44.7 bits (104), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 31/116 (26%), Positives = 56/116 (48%), Gaps = 3/116 (2%)
 Frame = +3

Query: 326 SETVATGEGLRQTIIGQ-PMSVTITTKDKDGELCKTGNAYLTAELSTPDGSVADGEILDN 384
           S+   +G G+R+++    P   T+ T+D        G A L   +  PDGS       +N
Sbjct: 492 SKVKVSGPGVRRSVPASLPAQFTVDTRD-------AGVADLECMVQRPDGSFIKPYFQNN 650

Query: 385 KNGTYEFLYTVQKEGDFTLSLRLYDQHIRGSPFKLKVIRSADVSP--TTEGVKRRV 438
           ++GTY+ +YT +  G + + ++   Q +  SPF ++     D S    T+G +R +
Sbjct: 651 EDGTYDVIYTPEDLGVYDIIVKYDGQDVPRSPFNVEATPLGDASQCRITDGAERVI 818

 Score = 35.0 bits (79), Expect = 0.10,   Method: Compositional matrix adjust.
 Identities = 16/46 (34%), Positives = 25/46 (54%)
 Frame = +3

Query: 383 DNKNGTYEFLYTVQKEGDFTLSLRLYDQHIRGSPFKLKVIRSADVS 428
           DN++GT    Y   K G + +S+   D+ I+ SPF +K+    D S
Sbjct: 63  DNRDGTCRVEYYPTKPGKYDISVLFGDKPIKDSPFSVKIQNPVDAS 200

 Score = 32.7 bits (73), Expect = 0.49,   Method: Compositional matrix adjust.
 Identities = 28/126 (22%), Positives = 48/126 (38%)
 Frame = +3

Query: 282 NELADQDFPLHPRENDQLDFIVETEGLKKSIHNLGTILTTNAVASETVATGEGLRQTIIG 341
           NE    D    P +    D IV+ +G            T    AS+   T    R   I 
Sbjct: 648 NEDGTYDVIYTPEDLGVYDIIVKYDGQDVPRSPFNVEATPLGDASQCRITDGAERVIPIE 827

Query: 342 QPMSVTITTKDKDGELCKTGNAYLTAELSTPDGSVADGEILDNKNGTYEFLYTVQKEGDF 401
           +   +T+   D        G   +T  + +P GS  D +I+D  +GT+   +  Q  G++
Sbjct: 828 KETVITVDAAD-------AGKGSVTCRIRSPSGSDIDIDIVDQGDGTFTISFIPQYAGEY 986

Query: 402 TLSLRL 407
            + ++ 
Sbjct: 987 IIEIKF 1004

 Score = 32.3 bits (72), Expect = 0.64,   Method: Compositional matrix adjust.
 Identities = 17/58 (29%), Positives = 31/58 (53%)
 Frame = +3

Query: 364  YLTAELSTPDGSVADGEILDNKNGTYEFLYTVQKEGDFTLSLRLYDQHIRGSPFKLKV 421
            +++A +  P G  +  +I DN++GT    Y   + G   L ++  ++ I+GSPF   V
Sbjct: 1197 FVSASVIMPSGKTSYPKIEDNRDGTVTVRYQPTETGLHELHVKYNNECIQGSPFFFHV 1370
>19277
          Length = 511

 Score = 44.3 bits (103), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 26/97 (26%), Positives = 47/97 (48%)
 Frame = +2

Query: 325 ASETVATGEGLRQTIIGQPMSVTITTKDKDGELCKTGNAYLTAELSTPDGSVADGEILDN 384
           AS+   +G+GL + +  +     + T++           Y    LS    S AD E  DN
Sbjct: 101 ASKVKVSGDGLTEGMANEVNEFVVDTREA---------GYGGMSLSIEGPSKADIECHDN 253

Query: 385 KNGTYEFLYTVQKEGDFTLSLRLYDQHIRGSPFKLKV 421
           ++GT    Y   + G + ++++  DQH+ GSP+ +K+
Sbjct: 254 EDGTCRVTYKPTEPGTYIINIKFADQHVPGSPYSVKI 364
>14625
          Length = 846

 Score = 43.1 bits (100), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 42/184 (22%), Positives = 70/184 (38%)
 Frame = +3

Query: 43  CERCLQNYIPAHSLTLSCPVCRQTSILPEKGVAALQNNFFITNLMDVLQRTPGSNGEDSS 102
           C  C  N  PA S  + C        +       +  +  +T+L + L    GS+G    
Sbjct: 75  CTGCESN--PATSFCVQCDDWLCADCVNAHKRVRMTKDHQLTSLEEALTNQGGSSGP--- 239

Query: 103 ILETVTAVAAGKPLSCPNHDGNVMEFYCQSCETAMCRECTEGEHAEHPTVPLKDVVEQHK 162
                T V+    + C  H    +  +C+ CE   CR+C   +H EH    L++  E +K
Sbjct: 240 -----TEVS----MLCRVHPKEKLTLFCEKCEVLTCRDCQLLQHQEHKYQFLQEAAESYK 392

Query: 163 ASLQVQLDAVNKRLPEIDSALQFISEIIHQLTNQKASIVDDIHSTFDELQKTLNVRKSVL 222
           A L   L  +  R   +      I E + ++  +K  +  DI    D + K +      +
Sbjct: 393 AKLTGSLSLMKDRREVLWRYQTEIEERLSKVKREKNDLQQDILRQADVIVKAVRTAVWAV 572

Query: 223 LMEL 226
           L  L
Sbjct: 573 LSSL 584
>20514
          Length = 803

 Score = 42.0 bits (97), Expect = 8e-04,   Method: Compositional matrix adjust.
 Identities = 35/126 (27%), Positives = 58/126 (46%), Gaps = 11/126 (8%)
 Frame = -2

Query: 463 RKENPIEDDLIFRVGTKG-----RNKGEFTNLQGVAASTSGKILIAD-SNNQCVQIFSN- 515
           +++ PI  + I  +G  G        G F    G+    +G I + D + +Q  +I +  
Sbjct: 451 KQDQPITQNTILILGPDGVFVRKFGAGRFFMPHGIEVDHAGNIWLTDVALHQVFRIPAGS 272

Query: 516 ---DGQFKSRFGIRGRSPGQLQRPTGVAVHPSGDIIIAD-YDNKWVSIFSNDGKFKTKIG 571
              D     RF + G       +P+ VAV PSG+  ++D Y N  +  FS DG+F  + G
Sbjct: 271 QEADLTLGERF-VHGDDHTHFCQPSDVAVLPSGEFFVSDGYCNSRIMKFSKDGQFLKQWG 95

Query: 572 SGKLMG 577
           S  ++G
Sbjct: 94  SPNIIG 77

 Score = 30.8 bits (68), Expect = 2.2,   Method: Compositional matrix adjust.
 Identities = 15/43 (34%), Positives = 24/43 (55%)
 Frame = -2

Query: 645 SVKVFNQEGEFMLKFGSNGEGNGQFNAPTGVAVDSNGNIIVAD 687
           ++ +   +G F+ KFG+     G+F  P G+ VD  GNI + D
Sbjct: 424 TILILGPDGVFVRKFGA-----GRFFMPHGIEVDHAGNIWLTD 311
>33436
          Length = 583

 Score = 42.0 bits (97), Expect = 8e-04,   Method: Composition-based stats.
 Identities = 17/46 (36%), Positives = 25/46 (54%)
 Frame = -1

Query: 21  LICSICLERYKNPKVLPCLHTFCERCLQNYIPAHSLTLSCPVCRQT 66
           L CSICLE   +P    C H FC  C+  ++     ++ CP+C+ T
Sbjct: 406 LECSICLELMTSPVATKCEHYFCRFCITEFLEKKR-SVPCPLCKAT 272
>20704
          Length = 874

 Score = 41.6 bits (96), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 21/61 (34%), Positives = 29/61 (47%)
 Frame = -1

Query: 10  SPVVRQIDKQFLICSICLERYKNPKVLPCLHTFCERCLQNYIPAHSLTLSCPVCRQTSIL 69
           S   R  DK    C +C E Y   K+LPC HT C +C+  ++        CP+CR   + 
Sbjct: 373 SMAARISDKSEFECPVCHEDYDQHKILPCKHTACHKCILTWLQKGGRNRGCPLCRVPILS 194

Query: 70  P 70
           P
Sbjct: 193 P 191
>16231
          Length = 1393

 Score = 39.7 bits (91), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 42/151 (27%), Positives = 67/151 (44%), Gaps = 9/151 (5%)
 Frame = +3

Query: 315 LGTILTTNAVASETVATGEGLRQTIIGQPMSVTITTKDKDGELCKT---GNAYLTAELST 371
            G  +   + A    ATG G+      QP  V +  KD+      T   G+  +  ++  
Sbjct: 654 FGVQVAPASNAKACYATGRGV------QPRGVRV--KDRADFYVHTKGAGDGEVAVQIIG 809

Query: 372 PDGSVADGEI--LDNKNGTYEFLYTVQKEGDFTLSLRLYDQHIRGSPFKLKVIRSADVSP 429
           P G     ++  + ++   +E +Y   K G++ +++   DQHI  SPFK+      +V P
Sbjct: 810 PGGVEEKCQLKKVPDQPEVWECVYNPSKPGNYIINITFGDQHISKSPFKI------EVGP 971

Query: 430 TTEGVKRRVKSPG--SGHVKQKAV--KRPAS 456
             E  K R   PG   G V+QKAV   RP +
Sbjct: 972 YKES-KIRAYGPGLEGGVVQQKAVLLWRPTA 1061

 Score = 31.6 bits (70), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 19/68 (27%), Positives = 31/68 (45%)
 Frame = +2

Query: 380  EILDNKNGTYEFLYTVQKEGDFTLSLRLYDQHIRGSPFKLKVIRSADVSPTTEGVKRRVK 439
            E LDN +G+ +  Y     G++ + +   D+ I  SPF       AD+ P  +    +V 
Sbjct: 1112 ECLDNGDGSADVWYLPTMPGEYAVHILCSDEDIPKSPFM------ADIKPAADFDAEKVI 1273

Query: 440  SPGSGHVK 447
            + G G  K
Sbjct: 1274 AKGPGLEK 1297
>20092
          Length = 467

 Score = 39.7 bits (91), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 26/70 (37%), Positives = 36/70 (51%), Gaps = 1/70 (1%)
 Frame = +1

Query: 516 DGQFKSRFGIRGRSPGQLQRPTGVAVHPSGDIIIADYDNKWVSIFSNDGKFKTKIGSG-K 574
           DG F+ R     +  G    PTGV V+  GD+I+AD  N  V I  N+G+   K G+  K
Sbjct: 250 DGLFEIRAKCVEKIRGDFDHPTGVCVNSKGDVIVADTANHVVKI-CNNGRVIKKFGADLK 426

Query: 575 LMGPKGVSVD 584
           +  P  V V+
Sbjct: 427 MWRPSAVVVN 456

 Score = 35.8 bits (81), Expect = 0.065,   Method: Compositional matrix adjust.
 Identities = 16/44 (36%), Positives = 27/44 (61%)
 Frame = +1

Query: 652 EGEFMLKFGSNGEGNGQFNAPTGVAVDSNGNIIVADWGNSRIQV 695
           +G F ++     +  G F+ PTGV V+S G++IVAD  N  +++
Sbjct: 250 DGLFEIRAKCVEKIRGDFDHPTGVCVNSKGDVIVADTANHVVKI 381

 Score = 35.4 bits (80), Expect = 0.092,   Method: Compositional matrix adjust.
 Identities = 22/74 (29%), Positives = 41/74 (55%), Gaps = 2/74 (2%)
 Frame = +1

Query: 471 DLIFRVGTKGRNK--GEFTNLQGVAASTSGKILIADSNNQCVQIFSNDGQFKSRFGIRGR 528
           D +F +  K   K  G+F +  GV  ++ G +++AD+ N  V+I  N+G+   +FG    
Sbjct: 250 DGLFEIRAKCVEKIRGDFDHPTGVCVNSKGDVIVADTANHVVKI-CNNGRVIKKFG---- 414

Query: 529 SPGQLQRPTGVAVH 542
           +  ++ RP+ V V+
Sbjct: 415 ADLKMWRPSAVVVN 456

 Score = 29.6 bits (65), Expect = 4.5,   Method: Compositional matrix adjust.
 Identities = 11/24 (45%), Positives = 16/24 (66%)
 Frame = +1

Query: 716 PQGLALTSDGHVVVADSGNHCFKV 739
           P G+ + S G V+VAD+ NH  K+
Sbjct: 310 PTGVCVNSKGDVIVADTANHVVKI 381
>27230
          Length = 583

 Score = 38.9 bits (89), Expect = 0.008,   Method: Composition-based stats.
 Identities = 26/84 (30%), Positives = 40/84 (47%)
 Frame = -1

Query: 361 GNAYLTAELSTPDGSVADGEILDNKNGTYEFLYTVQKEGDFTLSLRLYDQHIRGSPFKLK 420
           G   + A L+TP G      + + K+GTY  LYT  +EG  +L +      I GSPF++ 
Sbjct: 247 GQGEVEAILTTPSGRKLQTLVDNMKDGTYPVLYTPMEEGPQSLDVTYKGIPIPGSPFQVN 68

Query: 421 VIRSADVSPTTEGVKRRVKSPGSG 444
            +   D +        RV++ G G
Sbjct: 67  AVAGYDAN--------RVRAYGPG 20
>18540
          Length = 988

 Score = 38.5 bits (88), Expect = 0.011,   Method: Compositional matrix adjust.
 Identities = 30/110 (27%), Positives = 52/110 (47%), Gaps = 9/110 (8%)
 Frame = +3

Query: 621 QFAGPHFAAVNSNNEIIITD-FHNHSVKVFNQEGEFMLKFGSNGEGNGQ-------FNAP 672
            F  P   AV ++ +  ++D + N  V  F++EG  + ++G   +   +       F  P
Sbjct: 78  HFCKPTDVAVLASGDFFVSDGYCNSRVMKFSKEGNLLKQWGRPDQFRARIQPQPNVFTIP 257

Query: 673 TGVAVDSNGNII-VADWGNSRIQVFDGSGSFLSYINTSADPLYGPQGLAL 721
             +A+  + N++ VAD  N RIQ FD  G+F   I       +GP+  A+
Sbjct: 258 HSLALAEDLNLVCVADRENGRIQCFDLDGTFKFIIQHQQ---FGPRLFAI 398
>14716
          Length = 481

 Score = 38.1 bits (87), Expect = 0.012,   Method: Composition-based stats.
 Identities = 19/59 (32%), Positives = 28/59 (47%)
 Frame = +2

Query: 21  LICSICLERYKNPKVLPCLHTFCERCLQNYIPAHSLTLSCPVCRQTSILPEKGVAALQN 79
           L CS+CL   +   +  C H FC  C+  +    +    CP+CR+    P   + ALQN
Sbjct: 146 LKCSLCLGPRRRTTLTVCGHLFCWDCIHQWCQEKA---ECPLCREQ--FPPHRLVALQN 307
>10203
          Length = 2103

 Score = 37.4 bits (85), Expect = 0.020,   Method: Compositional matrix adjust.
 Identities = 16/44 (36%), Positives = 25/44 (56%)
 Frame = -2

Query: 23   CSICLERYKNPKVLPCLHTFCERCLQNYIPAHSLTLSCPVCRQT 66
            C+IC E  +  + LPC H F   CL++++   +   SCP CR +
Sbjct: 1109 CAICWEGMEAARKLPCGHLFHNSCLRSWLEQDT---SCPTCRMS 987
>29755
          Length = 460

 Score = 37.4 bits (85), Expect = 0.024,   Method: Composition-based stats.
 Identities = 16/37 (43%), Positives = 25/37 (67%)
 Frame = +3

Query: 386 NGTYEFLYTVQKEGDFTLSLRLYDQHIRGSPFKLKVI 422
           +G Y   YTV+++G + L +R  D++I GSPF + VI
Sbjct: 30  SGQYNINYTVKQQGSYMLIVRWGDENIPGSPFAVDVI 140
>27368
          Length = 394

 Score = 36.2 bits (82), Expect = 0.053,   Method: Composition-based stats.
 Identities = 15/45 (33%), Positives = 25/45 (55%)
 Frame = +1

Query: 21 LICSICLERYKNPKVLPCLHTFCERCLQNYIPAHSLTLSCPVCRQ 65
          L+C +C +   +P    C HTFC  CL++++   +L   CP  +Q
Sbjct: 4  LLCQLCHQPLVDPLETKCGHTFCTSCLKSHLAVQAL---CPEDKQ 129
>29288
          Length = 421

 Score = 34.7 bits (78), Expect = 0.14,   Method: Composition-based stats.
 Identities = 16/44 (36%), Positives = 25/44 (56%)
 Frame = -1

Query: 31  KNPKVLPCLHTFCERCLQNYIPAHSLTLSCPVCRQTSILPEKGV 74
           K+P +L C H+FC+ CL+        T+ CP C++ + L  K V
Sbjct: 406 KHPMLLRCGHSFCKPCLRKCETTED-TIQCPTCQKPTRLSLKTV 278
>33593
          Length = 559

 Score = 34.3 bits (77), Expect = 0.21,   Method: Composition-based stats.
 Identities = 19/78 (24%), Positives = 37/78 (47%)
 Frame = -3

Query: 1   MASEGASIPSPVVRQIDKQFLICSICLERYKNPKVLPCLHTFCERCLQNYIPAHSLTLSC 60
           +A    SI +   ++     + C +C +   +P  + C+H FC  C+ + + A   + +C
Sbjct: 446 LAPRSPSIQTXCQQRSRADLMECVVCGDWPIHPHHIGCIHXFCYFCIASNLKADP-SYTC 270

Query: 61  PVCRQTSILPEKGVAALQ 78
           P C Q  +  + GV + Q
Sbjct: 269 PACGQGKM--KDGVVSPQ 222
>18689
          Length = 723

 Score = 33.9 bits (76), Expect = 0.24,   Method: Composition-based stats.
 Identities = 13/22 (59%), Positives = 16/22 (72%)
 Frame = +2

Query: 26  CLERYKNPKVLPCLHTFCERCL 47
           CL +Y+N   LPCLHT CE C+
Sbjct: 104 CLTKYRN--FLPCLHTMCEDCI 163
>15938
          Length = 752

 Score = 33.9 bits (76), Expect = 0.24,   Method: Compositional matrix adjust.
 Identities = 16/45 (35%), Positives = 23/45 (51%)
 Frame = +1

Query: 23  CSICLERYKNPKVLPCLHTFCERCLQNYIPAHSLTLSCPVCRQTS 67
           C IC + + NP V  C H +CE+C    +  +  T  C VC Q +
Sbjct: 232 CFICRKSFVNPVVTKCKHYYCEKCA---LAQYKKTQRCFVCGQQT 357
>03240
          Length = 1683

 Score = 33.1 bits (74), Expect = 0.37,   Method: Compositional matrix adjust.
 Identities = 15/44 (34%), Positives = 21/44 (47%)
 Frame = -3

Query: 576 MGPKGVSVDRNGHIIVVDNKACCVFIFQPNGKIVTRFGSRGNGD 619
           + P  + +DRNGHI + D   C  F +  N K   R G+    D
Sbjct: 913 IKPDNILIDRNGHIKLTDFGLCTGFRWTHNSKYYQRDGTHARQD 782
>17930
          Length = 798

 Score = 32.7 bits (73), Expect = 0.57,   Method: Composition-based stats.
 Identities = 11/24 (45%), Positives = 15/24 (62%)
 Frame = -2

Query: 23 CSICLERYKNPKVLPCLHTFCERC 46
          C IC + + NP V  C H +CE+C
Sbjct: 98 CFICRKSFVNPVVTKCKHYYCEKC 27
>14417
          Length = 1383

 Score = 32.3 bits (72), Expect = 0.67,   Method: Compositional matrix adjust.
 Identities = 21/63 (33%), Positives = 30/63 (47%), Gaps = 3/63 (4%)
 Frame = +2

Query: 11  PVVRQIDKQFL---ICSICLERYKNPKVLPCLHTFCERCLQNYIPAHSLTLSCPVCRQTS 67
           PV+ Q+    L   + S+  ++  NPK LPC H FC  CL     A      CP C++  
Sbjct: 458 PVLPQVKLMSLTDAVPSVWKKKSHNPK-LPCGHRFCASCLDR---AMINNPRCPKCQRLY 625

Query: 68  ILP 70
            +P
Sbjct: 626 GIP 634
>21436
          Length = 546

 Score = 31.6 bits (70), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 15/45 (33%), Positives = 25/45 (55%)
 Frame = -1

Query: 384 NKNGTYEFLYTVQKEGDFTLSLRLYDQHIRGSPFKLKVIRSADVS 428
           N++GT+   Y  +  G +T+ +   D  +  SP K+KV  + DVS
Sbjct: 258 NQDGTFTVEYEPKLPGTYTVMVYFADVEVPSSPVKVKVEPNIDVS 124
>31249
          Length = 543

 Score = 31.6 bits (70), Expect = 1.3,   Method: Composition-based stats.
 Identities = 13/51 (25%), Positives = 24/51 (47%)
 Frame = -3

Query: 14  RQIDKQFLICSICLERYKNPKVLPCLHTFCERCLQNYIPAHSLTLSCPVCR 64
           R++     +C++CL      +V  C H F   C++  +   S    CP+C+
Sbjct: 367 RELKDHNDVCAVCLGSMGXARVTRCHHLFHAXCIRQLLEVSS---HCPLCK 224
>00178
          Length = 944

 Score = 31.2 bits (69), Expect = 1.7,   Method: Compositional matrix adjust.
 Identities = 12/28 (42%), Positives = 18/28 (64%)
 Frame = -1

Query: 353 KDGELCKTGNAYLTAELSTPDGSVADGE 380
           +DGELC+ G  +   EL T DG+ ++G 
Sbjct: 458 QDGELCQGGLVWRHGELRTADGTASNGH 375
>07523
          Length = 1299

 Score = 31.2 bits (69), Expect = 1.7,   Method: Compositional matrix adjust.
 Identities = 14/43 (32%), Positives = 22/43 (51%), Gaps = 1/43 (2%)
 Frame = -1

Query: 23  CSICLERYKNPKVLPCLH-TFCERCLQNYIPAHSLTLSCPVCR 64
           C IC+   ++  +LPC H   C  C ++     S+   CP+CR
Sbjct: 456 CVICMSDMRDTLILPCRHLCLCSACAESLRYQASM---CPICR 337
>27069
          Length = 653

 Score = 30.4 bits (67), Expect = 2.9,   Method: Composition-based stats.
 Identities = 16/54 (29%), Positives = 27/54 (50%), Gaps = 2/54 (3%)
 Frame = -2

Query: 104 LETVTAVAAGKPLSCPNHDGNVMEFYCQSCETAMCRECTEGEHAE--HPTVPLK 155
           ++ + A  A     C ++D ++ EF C +  T+ CR  T   H E  +P VP +
Sbjct: 361 VDVINASTAASTTPCFDYDVSISEFAC*TSHTSPCRH-TAAVHGECDYPAVPAR 203
>26463
          Length = 756

 Score = 30.0 bits (66), Expect = 3.4,   Method: Compositional matrix adjust.
 Identities = 12/32 (37%), Positives = 16/32 (50%)
 Frame = -2

Query: 118 CPNHDGNVMEFYCQSCETAMCRECTEGEHAEH 149
           C  H+  ++  YC +C    C  C E EHA H
Sbjct: 197 CHLHENELLSVYCVTCMVTYCDTCVEKEHAGH 102
>23915
          Length = 1006

 Score = 29.3 bits (64), Expect = 6.0,   Method: Compositional matrix adjust.
 Identities = 20/64 (31%), Positives = 34/64 (53%), Gaps = 4/64 (6%)
 Frame = +1

Query: 536 PTGVAVHPSGDIIIADYDNKWVSIFSND----GKFKTKIGSGKLMGPKGVSVDRNGHIIV 591
           P  VAV  +GDII++D   +++ IFS+D      +++ +   +L    GV  D  G + +
Sbjct: 208 PMDVAVAGNGDIIVSDA-GRFIQIFSSDFVLKKSYQSPLADSELW---GVCTDPGGSVYI 375

Query: 592 VDNK 595
            D K
Sbjct: 376 ADWK 387
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|146219837|ref|NP_034253.3| eukaryotic translation
initiation factor 3, subunit 10 (theta) [Mus musculus]
         (1344 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

09075                                                                 344   2e-94
20901                                                                 322   5e-88
08309                                                                  30   0.13 
01023                                                                  32   1.6  
12696                                                                  30   4.9  
>09075
          Length = 960

 Score =  344 bits (882), Expect = 2e-94,   Method: Compositional matrix adjust.
 Identities = 166/296 (56%), Positives = 221/296 (74%)
 Frame = +1

Query: 244 ELWQEAFKAVEDIHGLFSLSKKPPKPQLMANYYNKVSTVFWKSGNALFHASTLHRLYHLS 303
           ELWQEAFKAVEDIHGL +LSKK PKP LMANYY K+  VF KSGN LFHA+TLHRL++LS
Sbjct: 1   ELWQEAFKAVEDIHGLITLSKKQPKPSLMANYYQKLGLVFAKSGNHLFHATTLHRLFNLS 180

Query: 304 REMRKNLTQEEMQRMSTRVLLATLSIPITPERTDIARLLDMDGIIVEKQRRLATLLGLQA 363
           RE RKNL+ EE+Q+M+ RV+ ATL+IPI   R  +  LL MD   ++KQRRLATLL L +
Sbjct: 181 REQRKNLSPEELQKMANRVVCATLAIPIPASRNAVDSLLAMDETGIDKQRRLATLLMLPS 360

Query: 364 PPTRIGLINDMVRFSVLQYVVPEVKDLYNWLEVEFNPLKLCERVTKVLNWVREQPEKEPE 423
           PPTR  L+ D+V++  LQYV  E+++LY +LEV+F+PL+L   V  ++ ++        +
Sbjct: 361 PPTRQNLVKDLVKYGSLQYVTQELQNLYKYLEVDFHPLRLYPAVQPIIQFI----GANED 528

Query: 424 LQQYVPQLQNNTILRLLQQVAQIYQSIEFSRLTSLVPFVDAFQLERAIVDAARHCDLQVR 483
           L  YVP ++   I R+L+QV+Q+YQ+IEF R  SLVPF D F+LER IV AA++ +LQVR
Sbjct: 529 LAMYVPHMEEIIIARVLKQVSQVYQTIEFKRFASLVPFADKFKLERIIVGAAKNMELQVR 708

Query: 484 IDHTSRTLSFGSDLNYATREDAPVGPHLQSMPSEQIRNQLTAMSSVLAKALEVIRP 539
           +DH + +LSFG+DL  + +++   GP +QSMPSEQIRNQLTA+  VL++A+ VI P
Sbjct: 709 VDHRTLSLSFGTDLGLSQKDETAEGPTIQSMPSEQIRNQLTALGRVLSQAVRVIAP 876
>20901
          Length = 1121

 Score =  322 bits (826), Expect = 5e-88,   Method: Compositional matrix adjust.
 Identities = 159/201 (79%), Positives = 170/201 (84%)
 Frame = -3

Query: 1    MPAYFQRPENALKRANEFLEVGKKQPALDVLYDVMKSKKHRTWQKIHEPIMLKYLELCVD 60
            MP YFQRPENALKRANEF++VGK Q ALD LYDV+KSKKHRTWQKIHEPIM KYLELCVD
Sbjct: 1029 MPTYFQRPENALKRANEFIDVGKAQRALDALYDVIKSKKHRTWQKIHEPIMEKYLELCVD 850

Query: 61   LRKSHLAKEGLYQYKNICQQVNIKSLEDVVRAYXXXXXXXXXXXXXXSQQMVLDIEDLDN 120
            LRKSH+AKEGLYQYKNICQQVNI SL DVVR Y              S Q VLDI+DLD 
Sbjct: 849  LRKSHIAKEGLYQYKNICQQVNINSLVDVVRKYIALAEERTEAARQESHQTVLDIDDLDL 670

Query: 121  IQTPESVLLSAVSGEDTQDRTDRLLLTPWVKFLWESYRQCLDLLRNNSRVERLYHDIAQQ 180
              +PES+LL AVSGEDTQDRTDR +LTPWVKFLWESYRQCLDLLRNNSRVERLY DIAQQ
Sbjct: 669  PDSPESLLLKAVSGEDTQDRTDRAILTPWVKFLWESYRQCLDLLRNNSRVERLYQDIAQQ 490

Query: 181  AFKFCLQYTRKAEFRKLCDNL 201
            AFKFCL+Y+RK EFRKLCDN+
Sbjct: 489  AFKFCLKYSRKTEFRKLCDNV 427

 Score = 37.0 bits (84), Expect = 0.048,   Method: Composition-based stats.
 Identities = 15/25 (60%), Positives = 19/25 (76%)
 Frame = -1

Query: 201 LRMHLSQIQRHHNQSTAINLNNPES 225
           LR HL  + +H +Q TAINLNNP+S
Sbjct: 77  LRTHLGHVYKHQHQQTAINLNNPDS 3
>08309
          Length = 469

 Score = 30.4 bits (67), Expect(2) = 0.13,   Method: Composition-based stats.
 Identities = 13/14 (92%), Positives = 14/14 (100%)
 Frame = -1

Query: 234 LVQLDSAISMELWQ 247
           LVQLDSAI+MELWQ
Sbjct: 436 LVQLDSAINMELWQ 395

 Score = 23.9 bits (50), Expect(2) = 0.13,   Method: Compositional matrix adjust.
 Identities = 9/13 (69%), Positives = 11/13 (84%)
 Frame = -2

Query: 223 PESQSMHLETRLV 235
           P+SQ+MHLET L 
Sbjct: 468 PDSQAMHLETALC 430
>01023
          Length = 2030

 Score = 32.0 bits (71), Expect = 1.6,   Method: Composition-based stats.
 Identities = 24/75 (32%), Positives = 35/75 (46%), Gaps = 1/75 (1%)
 Frame = +1

Query: 233 RLVQLDSAISMELWQEAFKAVEDIHGLFSLSKKPPKPQLMANYY-NKVSTVFWKSGNALF 291
           RLVQ+D  +S+     A +     +GL    +  P PQL  +Y  N +    W     LF
Sbjct: 274 RLVQIDHVVSLVRLCSAKRDSRKKNGLDDF*RLAPAPQLCEHYTKNVICCSRW----VLF 441

Query: 292 HASTLHRLYHLSREM 306
            AS L +   +SRE+
Sbjct: 442 FASRLKKCATISREL 486
>12696
          Length = 3296

 Score = 30.4 bits (67), Expect = 4.9,   Method: Compositional matrix adjust.
 Identities = 13/17 (76%), Positives = 16/17 (94%)
 Frame = -3

Query: 294  STLHRLYHLSREMRKNL 310
            +TLHRL++LSRE RKNL
Sbjct: 3294 TTLHRLFNLSREQRKNL 3244
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|148747410|ref|NP_666097.3| archain 1 [Mus musculus]
         (511 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

14416                                                                 257   2e-94
04701                                                                  26   2.6  
>14416
          Length = 1343

 Score =  257 bits (656), Expect(2) = 2e-94,   Method: Compositional matrix adjust.
 Identities = 113/182 (62%), Positives = 148/182 (81%), Gaps = 1/182 (0%)
 Frame = -3

Query: 331  PNVDKKLFTAESLIGLKNPEKSFPVNSDVGVLKWRLQTTEESFIPLTINCWPSESGNGCD 390
            PNVDKKLF A S + LKNP+K FP+N DVGVLKWRLQT +E+ IPL+INCWPSES +GC+
Sbjct: 1047 PNVDKKLFLATSQVALKNPDKPFPLNQDVGVLKWRLQTQDEALIPLSINCWPSESSSGCE 868

Query: 391  VNIEYELQEDNLELNDVVITIPLPSGVGAPVIGEIDGEYRHDSRRNTLEWCLPVIDAKNK 450
            VNIEYEL++ +++L DVVI+IP PSG+G+PV+G+ DG+Y +D+ +  L+W LP IDA NK
Sbjct: 867  VNIEYELEQADMQLEDVVISIPCPSGMGSPVVGDCDGDYHYDTHKKHLQWSLPFIDATNK 688

Query: 451  SGSLEFSI-PGQPNDFFPVQVSFISKKNYCNIQVTKVTQVDGNSPVRFSTETTFLVDKYE 509
            SGSLEF++  G P+DFFPV VSF SKK YC+IQVT+V Q+  + P +FS++  F VD+YE
Sbjct: 687  SGSLEFTMHGGHPDDFFPVNVSFTSKKPYCDIQVTEVKQLADDQPEKFSSDVVFFVDRYE 508

Query: 510  IL 511
            I+
Sbjct: 507  IV 502

 Score =  107 bits (267), Expect(2) = 2e-94,   Method: Compositional matrix adjust.
 Identities = 50/102 (49%), Positives = 76/102 (74%), Gaps = 1/102 (0%)
 Frame = -1

Query: 231  KGKEVDNFVDKLKSEGETIMSSNMGKRTSEA-TKVHAPPINMESVHMKIEEKITLTCGRD 289
            K K+VD FV +++ EGE ++  + G++ S A +K   P +N ESVH+ IEEK+ LT GRD
Sbjct: 1343 KKKDVDTFVGQIQLEGEKVV--DAGRQGSSAISKSSTPAVNQESVHISIEEKMVLTAGRD 1170

Query: 290  GGLQNMELHGMIMLRISDDKFGRIRLHVENEDKKGVQLQTHP 331
            GGLQN+E+HG++ L++++D  GRI++   N+D KG+Q+QTHP
Sbjct: 1169 GGLQNLEVHGIMKLKVAEDXVGRIKVCTINKDNKGIQIQTHP 1044
>04701
          Length = 4543

 Score = 25.8 bits (55), Expect(2) = 2.6,   Method: Compositional matrix adjust.
 Identities = 20/77 (25%), Positives = 36/77 (46%), Gaps = 5/77 (6%)
 Frame = +3

Query: 5   AAAVCTKAGKAIVSRQFVEMTRTRIE-GLLAAFPKLMNTGKQHT----FVETESVRYVYQ 59
           A  +    GK ++SR +    R  I+  ++  F  L+  G+  +     +   +V +VY 
Sbjct: 99  AIYILDVKGKVLISRNY----RGDIDMSVIDKFMPLVMEGEDDSNVTPIISHGNVTFVYI 266

Query: 60  PMEKLYMVLITTKNSNI 76
               LY+V  T KN+N+
Sbjct: 267 KYNNLYLVSTTRKNANV 317

 Score = 22.3 bits (46), Expect(2) = 2.6,   Method: Compositional matrix adjust.
 Identities = 10/30 (33%), Positives = 16/30 (53%)
 Frame = +2

Query: 92  EYCRALEENEISEHCFDLIFAFDEIVALGY 121
           EY + LEE  I ++   +    DE++  GY
Sbjct: 362 EYFKELEEESIRDNFVIIYELLDEVMDFGY 451
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|19526826|ref|NP_598433.1| vacuolar protein sorting 26
isoform a [Mus musculus]
         (327 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

01953                                                                 341   2e-94
01034                                                                 249   1e-66
13123                                                                  63   2e-10
05131                                                                  44   1e-04
08430                                                                  28   4.4  
29983                                                                  28   4.5  
10713                                                                  27   8.0  
>01953
          Length = 1732

 Score =  341 bits (874), Expect = 2e-94,   Method: Compositional matrix adjust.
 Identities = 167/227 (73%), Positives = 194/227 (85%), Gaps = 6/227 (2%)
 Frame = -2

Query: 100  ELTQSRSYDFEFMQVEKPYESYIGANVRLRYFLKVTIVRRLTDLVKEYDLIVHQLATYPD 159
            +LT ++SY FEF QVEKPYESY GANVRLRYFL+VTIV+R++D+VKE D++VH L+ YPD
Sbjct: 1731 DLTHNQSYPFEFQQVEKPYESYTGANVRLRYFLRVTIVKRISDVVKEQDIVVHTLSQYPD 1552

Query: 160  VNNSIKMEVGIEDCLHIEFEYNKSKYHLKDVIVGKIYFLLVRIKIQHMELQLIKKEITGI 219
            +NNSIKMEVGIEDCLHIEFEYNKSKYHLKDVIVGKIYFLLVRIKI+HMELQ+IK+E TG 
Sbjct: 1551 MNNSIKMEVGIEDCLHIEFEYNKSKYHLKDVIVGKIYFLLVRIKIKHMELQVIKRETTGT 1372

Query: 220  GPSTTTETETIAKYEIMDGAPVKGESIPIRLFLAGYDPTPTMRDVNKKFSVRYFLNLVLV 279
            GP+T  E ETIAKYEIMDGAPV+GESIPIRLFL+GY+ TP+MRD+NKKFSV+Y+LNLVLV
Sbjct: 1371 GPNTFNENETIAKYEIMDGAPVRGESIPIRLFLSGYELTPSMRDINKKFSVKYYLNLVLV 1192

Query: 280  DEEDRRYFKQQEIILWRKAPEKLRKQRTNF------HQRFESPDSQA 320
            DEE+RRYFKQQEII++RKA      QR N+      HQ    P   A
Sbjct: 1191 DEEERRYFKQQEIIIFRKA----DXQRKNYQMALQHHQPVNPPQGFA 1063
>01034
          Length = 522

 Score =  249 bits (636), Expect = 1e-66,   Method: Compositional matrix adjust.
 Identities = 114/155 (73%), Positives = 139/155 (89%)
 Frame = -1

Query: 69  RIEFVGQIELFNDKSNTHEFVNLVKELALPGELTQSRSYDFEFMQVEKPYESYIGANVRL 128
           ++EF+GQIEL+ D+ N HEF +LVKELA PG+LT ++SY FEF QVEKPYESY GANVRL
Sbjct: 465 KVEFIGQIELYYDRGNHHEFTSLVKELARPGDLTHNQSYPFEFQQVEKPYESYTGANVRL 286

Query: 129 RYFLKVTIVRRLTDLVKEYDLIVHQLATYPDVNNSIKMEVGIEDCLHIEFEYNKSKYHLK 188
           RYFL+VTIV+R++D+VKE D++VH L+ YPD+NNSIKMEVGIEDCLHIEFEYNKSKYHLK
Sbjct: 285 RYFLRVTIVKRISDVVKEQDIVVHTLSQYPDMNNSIKMEVGIEDCLHIEFEYNKSKYHLK 106

Query: 189 DVIVGKIYFLLVRIKIQHMELQLIKKEITGIGPST 223
           D IVGKIYFLLVRIKI++MEL ++++E TG GP+T
Sbjct: 105 DAIVGKIYFLLVRIKIRYMELAIVRRETTGAGPNT 1
>13123
          Length = 523

 Score = 62.8 bits (151), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 26/48 (54%), Positives = 38/48 (79%)
 Frame = +3

Query: 176 IEFEYNKSKYHLKDVIVGKIYFLLVRIKIQHMELQLIKKEITGIGPST 223
           + + +  ++YHLKD IVGKIYFLLVRIKI++MEL ++++E TG G + 
Sbjct: 186 LTWSWWTARYHLKDAIVGKIYFLLVRIKIRYMELAIVRRETTGAGTAA 329
>05131
          Length = 864

 Score = 43.9 bits (102), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 40/169 (23%), Positives = 74/169 (43%), Gaps = 14/169 (8%)
 Frame = +1

Query: 118 YESYIGANVRLRYFLKVTIVRRL--TDLVKEYDLIVH-----QLATYPDVNNSIKME--V 168
           YE+Y G  V ++Y ++V + R L   DL K+ + I+      + A    VN SI  E   
Sbjct: 70  YETYHGVFVNIQYMIRVEMKRSLLNKDLQKQCEFIIEYKSQEEKAKPKPVNFSISPETLA 249

Query: 169 GIEDCLHI-----EFEYNKSKYHLKDVIVGKIYFLLVRIKIQHMELQLIKKEITGIGPST 223
           G+++  +I     + +   S   + D + G++      + ++ +E+Q+++ E  G     
Sbjct: 250 GVKEKQNIPKFKVKGKLESSCVKITDPLKGELVLEHCEVPVKSIEIQMVRVETCGCAEGY 429

Query: 224 TTETETIAKYEIMDGAPVKGESIPIRLFLAGYDPTPTMRDVNKKFSVRY 272
             +   I   +I DG   +  +IPI +        PT+   N K    Y
Sbjct: 430 AKDATEIQNIQIADGDVCRNLAIPIYMIFPRLFTCPTLSTNNFKIGDTY 576
>08430
          Length = 1632

 Score = 28.5 bits (62), Expect = 4.4,   Method: Compositional matrix adjust.
 Identities = 15/40 (37%), Positives = 23/40 (57%)
 Frame = +1

Query: 142 DLVKEYDLIVHQLATYPDVNNSIKMEVGIEDCLHIEFEYN 181
           DL+ E  ++    A + D N SI + V IE CL+ +F Y+
Sbjct: 361 DLMLEPVVMAKFQAPHDDANLSIMVLVDIESCLYCQFRYS 480
>29983
          Length = 1021

 Score = 28.1 bits (61), Expect = 4.5,   Method: Compositional matrix adjust.
 Identities = 15/52 (28%), Positives = 27/52 (51%)
 Frame = -1

Query: 257 PTPTMRDVNKKFSVRYFLNLVLVDEEDRRYFKQQEIILWRKAPEKLRKQRTN 308
           P P ++D N   ++RY+L + L +E+     + Q    W+K   +   Q+TN
Sbjct: 763 PHPKIKDSNNNENMRYWLQMNLENEDSLINQELQNDTYWQKLKRQXYSQQTN 608
>10713
          Length = 1615

 Score = 27.3 bits (59), Expect = 8.0,   Method: Compositional matrix adjust.
 Identities = 10/24 (41%), Positives = 15/24 (62%)
 Frame = -1

Query: 280 DEEDRRYFKQQEIILWRKAPEKLR 303
           +++D RYF  Q   +W K P+ LR
Sbjct: 538 NQQDXRYFSFQAPTIWNKLPDSLR 467
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|21313510|ref|NP_079793.1| RNA terminal phosphate
cyclase domain 1 [Mus musculus]
         (366 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

09492                                                                 341   3e-94
00302                                                                  30   1.8  
29742                                                                  28   5.1  
>09492
          Length = 1754

 Score =  341 bits (874), Expect = 3e-94,   Method: Compositional matrix adjust.
 Identities = 159/284 (55%), Positives = 215/284 (75%)
 Frame = +2

Query: 83  KIRGGVHTADTKTAGSVCLLMQVSMPCVLFAASPSELRLKGGTNAEMAPQIDYTMMVFKP 142
           +I+ G + ADTKTAGS+CLLMQ ++PC+LF  +P+++ ++GGTNA+MAPQ+DYTMMVF+P
Sbjct: 2   QIKAGSYRADTKTAGSICLLMQAALPCLLFGGAPTQVSIRGGTNADMAPQVDYTMMVFQP 181

Query: 143 IAEKFGFTFNCDIKTRGYYPKGGGEVIVRVSPVKRLDPINLTDRGSVTKIYGRAFVAGVL 202
           +AEKFG  F C+IK RGYYPKGGGEV+    P+K L    +T+RG VT+IYGR+FVAGVL
Sbjct: 182 MAEKFGMKFECEIKKRGYYPKGGGEVMTTSYPLKVLSATEITNRGEVTRIYGRSFVAGVL 361

Query: 203 PLKVAKDMAAAAVRCIRKEIRDLYVSIQPVQEARDQAFGNGSGIIIVAETSTGCLFAGSS 262
           P+K+A  M  +A R +R++   + + I+ ++E    A GNG+GII+VAET+TGCL AGS+
Sbjct: 362 PMKIAHTMVQSAERLLRQDGACIPIQIEALKEPEHAALGNGTGIILVAETTTGCLLAGSA 541

Query: 263 LGKRGVNADKAGIEAAEMLLANLRHGGTVDEYLQDQLIIFMALANGISRIKTGSVTLHTQ 322
           LGK+GV A+K G +AA ML++NL HGG VDEYLQDQLI+ MALA G SR+  G V+LHT+
Sbjct: 542 LGKKGVPAEKVGADAAHMLISNLHHGGCVDEYLQDQLILLMALARGKSRVLCGPVSLHTE 721

Query: 323 TAIHFAEQLAKAKFTVKKSEEEEDATKDTYVIECEGIGMANPHL 366
           TAIH A+ L +A+F ++K  E       T +IEC+GIG  N  +
Sbjct: 722 TAIHVAKLLTQAQFKIEKVSE------TTNMIECDGIGHENSQM 835
>00302
          Length = 927

 Score = 29.6 bits (65), Expect = 1.8,   Method: Compositional matrix adjust.
 Identities = 23/72 (31%), Positives = 31/72 (43%)
 Frame = -2

Query: 21  RVSTALSCLLGLPLRVQKIRAGRSTPGLRPQHLSGLEMVRDLCGGHLEGAEIGSTEITFT 80
           + ST L  LL + L  Q   A    PGL P H+   +   D     +EGA++        
Sbjct: 812 KCSTNLH-LLNIKLPKQMAMAANLVPGLAPNHVHDPDPGPDTGTAKVEGADLAH---ALV 645

Query: 81  PEKIRGGVHTAD 92
           P  I+G V  AD
Sbjct: 644 PALIQGAVTVAD 609
>29742
          Length = 351

 Score = 28.1 bits (61), Expect = 5.1,   Method: Composition-based stats.
 Identities = 15/33 (45%), Positives = 18/33 (54%)
 Frame = -2

Query: 185 DRGSVTKIYGRAFVAGVLPLKVAKDMAAAAVRC 217
           DRG+V ++ G AFVA V  L V       AV C
Sbjct: 260 DRGAVLEMQGVAFVAHVTDLTVQSRRVVCAVTC 162
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6671539|ref|NP_031464.1| fructose-bisphosphate
aldolase A [Mus musculus]
         (364 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

12684                                                                 211   4e-94
32571                                                                 162   3e-54
04687                                                                 114   6e-26
01154                                                                  89   3e-18
19270                                                                  49   3e-06
09977                                                                  28   8.5  
25431                                                                  27   8.9  
>12684
          Length = 1376

 Score =  211 bits (536), Expect(2) = 4e-94,   Method: Compositional matrix adjust.
 Identities = 97/124 (78%), Positives = 112/124 (90%)
 Frame = +1

Query: 119 TNGETTTQGLDGLSERCAQYKKDGADFAKWRCVLKIGEHTPSALAIMENANVLARYASIC 178
           ++ E+TTQGLDGLSERCAQYKKDGA FAKWRCVLKI ++TPS  A+MENANVLARYASIC
Sbjct: 1   SHDESTTQGLDGLSERCAQYKKDGAQFAKWRCVLKISKNTPSHQAMMENANVLARYASIC 180

Query: 179 QQNGIVPIVEPEILPDGDHDLKRCQYVTEKVLAAVYKALSDHHVYLEGTLLKPNMVTPGH 238
           QQNG+VPIVEPE+LPDG+HDL+  Q VTE+VLA  YKALS+HHVYLEG+LLKPNMVT G 
Sbjct: 181 QQNGLVPIVEPEVLPDGEHDLETAQKVTEQVLAYTYKALSEHHVYLEGSLLKPNMVTAGQ 360

Query: 239 ACTQ 242
           AC++
Sbjct: 361 ACSK 372

 Score =  152 bits (383), Expect(2) = 4e-94,   Method: Compositional matrix adjust.
 Identities = 80/122 (65%), Positives = 90/122 (73%)
 Frame = +2

Query: 243 KFSNEEIAMATVTALRRTVPPAVTGVTFLSGGQSEEEASINLNAINKCPLLKPWALTFSY 302
           K S+E+IA+ATVTAL R VP AV G+ FLSGGQSEE+A+INL+AINK     PWALTFSY
Sbjct: 371 KVSHEQIAIATVTALSRXVPGAVPGICFLSGGQSEEDATINLDAINKYKGKNPWALTFSY 550

Query: 303 GRALQASALKAWGGKKENLKAAQEEYIKRALANSLACQGKYTPSGQSGAAASESLFISNH 362
           GRALQAS LKAW G K N  AAQ E +KRA AN  AC GKY   G  G A  ESLF++ H
Sbjct: 551 GRALQASVLKAWKGNKANTDAAQGELLKRAKANGEACVGKYA-GGVKGTAGGESLFVAGH 727

Query: 363 AY 364
           AY
Sbjct: 728 AY 733
>32571
          Length = 515

 Score =  162 bits (411), Expect(2) = 3e-54,   Method: Compositional matrix adjust.
 Identities = 75/93 (80%), Positives = 84/93 (90%)
 Frame = -1

Query: 115 PLAGTNGETTTQGLDGLSERCAQYKKDGADFAKWRCVLKIGEHTPSALAIMENANVLARY 174
           PLAG++ E TTQGLDGLSERCAQYKKDGA FAKWRCVLKI ++TPS  A+MENANVLARY
Sbjct: 446 PLAGSHNECTTQGLDGLSERCAQYKKDGAQFAKWRCVLKISKNTPSYQAMMENANVLARY 267

Query: 175 ASICQQNGIVPIVEPEILPDGDHDLKRCQYVTE 207
           ASICQQNG+VPIVEPE+LPDG+HDL+  Q VTE
Sbjct: 266 ASICQQNGLVPIVEPEVLPDGEHDLQTAQKVTE 168

 Score = 67.4 bits (163), Expect(2) = 3e-54,   Method: Compositional matrix adjust.
 Identities = 30/44 (68%), Positives = 38/44 (86%)
 Frame = -2

Query: 208 KVLAAVYKALSDHHVYLEGTLLKPNMVTPGHACTQKFSNEEIAM 251
           +VLA  YKAL+DHHV+LEGTLLKPNMVT G +C  K+S+E+IA+
Sbjct: 166 QVLAFQYKALADHHVFLEGTLLKPNMVTAGQSCATKYSHEQIAV 35
>04687
          Length = 1330

 Score =  114 bits (285), Expect = 6e-26,   Method: Compositional matrix adjust.
 Identities = 62/97 (63%), Positives = 72/97 (74%)
 Frame = +2

Query: 268 VTFLSGGQSEEEASINLNAINKCPLLKPWALTFSYGRALQASALKAWGGKKENLKAAQEE 327
           +TFLSGGQSEE+A+INL+AINK     PWA+TFSYGRALQAS L AW GKKEN+ AAQ E
Sbjct: 2   ITFLSGGQSEEDATINLDAINKYKGKNPWAVTFSYGRALQASVLAAWKGKKENVAAAQAE 181

Query: 328 YIKRALANSLACQGKYTPSGQSGAAASESLFISNHAY 364
            + R  ANS AC GKY      GAA  +SLF++ HAY
Sbjct: 182 LLARGKANSEACVGKYAGG-VQGAAGGQSLFVAGHAY 289
>01154
          Length = 2463

 Score = 89.0 bits (219), Expect = 3e-18,   Method: Compositional matrix adjust.
 Identities = 46/70 (65%), Positives = 49/70 (70%)
 Frame = -2

Query: 295  PWALTFSYGRALQASALKAWGGKKENLKAAQEEYIKRALANSLACQGKYTPSGQSGAAAS 354
            PWALTFSYGRALQAS LKAW G K N  AAQ E +KRA AN  AC GKY   G  G A  
Sbjct: 2462 PWALTFSYGRALQASVLKAWKGNKANTDAAQGELLKRAKANGEACVGKY-AGGVKGTAGG 2286

Query: 355  ESLFISNHAY 364
            ESLF++ HAY
Sbjct: 2285 ESLFVAGHAY 2256
>19270
          Length = 442

 Score = 49.3 bits (116), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 22/42 (52%), Positives = 31/42 (73%)
 Frame = -1

Query: 165 MENANVLARYASICQQNGIVPIVEPEILPDGDHDLKRCQYVT 206
           ++N++V   +     QNG+VPIVEPE+LPDG+HDL+  Q VT
Sbjct: 115 LDNSHVCMTFV----QNGLVPIVEPEVLPDGEHDLQTAQKVT 2
>09977
          Length = 1760

 Score = 27.7 bits (60), Expect = 8.5,   Method: Compositional matrix adjust.
 Identities = 10/31 (32%), Positives = 17/31 (54%)
 Frame = -1

Query: 289 KCPLLKPWALTFSYGRALQASALKAWGGKKE 319
           KCP++ P+    + G  L+ +  K WG  K+
Sbjct: 935 KCPIVNPFHTLLNNGETLEETEWKKWGRTKD 843
>25431
          Length = 1623

 Score = 27.3 bits (59), Expect = 8.9,   Method: Compositional matrix adjust.
 Identities = 18/51 (35%), Positives = 25/51 (49%), Gaps = 1/51 (1%)
 Frame = +2

Query: 120 NGETTTQGLDGL-SERCAQYKKDGADFAKWRCVLKIGEHTPSALAIMENAN 169
           NG  T    D L S + A+   +GAD     C LKI    P+ L +++N N
Sbjct: 161 NGVQTMVEFDNLESAKRAKQSLNGADVYSGCCTLKIEYAKPTRLNVVKNDN 313
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|164663791|ref|NP_035231.2| protein kinase C, alpha
[Mus musculus]
         (672 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

18484                                                                 289   4e-93
30755                                                                 216   3e-56
18663                                                                 179   5e-45
25445                                                                 175   4e-44
03240                                                                 164   7e-41
00486                                                                 148   8e-36
26156                                                                 109   1e-31
27405                                                                 117   2e-26
25019                                                                  80   2e-25
12721                                                                 110   1e-24
31885                                                                 107   2e-23
26560                                                                 102   4e-22
09606                                                                 101   9e-22
17722                                                                 100   4e-21
13066                                                                  99   5e-21
14420                                                                  99   5e-21
18921                                                                  99   7e-21
06405                                                                  96   5e-20
15910                                                                  94   2e-19
00300                                                                  94   2e-19
13592                                                                  86   4e-17
01707                                                                  85   1e-16
01392                                                                  82   6e-16
21808                                                                  80   2e-15
01060                                                                  80   3e-15
21079                                                                  79   6e-15
13212                                                                  78   1e-14
29581                                                                  76   4e-14
14126                                                                  72   7e-13
01756                                                                  70   2e-12
27546                                                                  70   3e-12
16549                                                                  70   4e-12
28638                                                                  53   4e-12
21433                                                                  69   6e-12
19094                                                                  69   7e-12
32957                                                                  68   1e-11
00392                                                                  68   1e-11
14116                                                                  67   2e-11
04852                                                                  66   4e-11
37602                                                                  65   7e-11
29179                                                                  65   9e-11
04591                                                                  63   3e-10
17591                                                                  52   3e-10
09007                                                                  63   4e-10
11185                                                                  62   6e-10
38560                                                                  62   8e-10
07940                                                                  60   4e-09
26711                                                                  59   7e-09
12672                                                                  58   1e-08
30339                                                                  58   2e-08
31935                                                                  57   3e-08
35187                                                                  57   4e-08
17300                                                                  56   5e-08
01966                                                                  56   6e-08
03508                                                                  55   9e-08
19761                                                                  55   9e-08
33586                                                                  47   1e-07
12786                                                                  55   1e-07
29590                                                                  54   2e-07
04138                                                                  54   2e-07
26525                                                                  54   3e-07
11353                                                                  54   3e-07
00715                                                                  53   4e-07
17975                                                                  53   4e-07
01718                                                                  53   5e-07
07291                                                                  52   6e-07
19301                                                                  52   9e-07
19361                                                                  52   1e-06
11780                                                                  47   2e-06
30040                                                                  51   2e-06
20640                                                                  51   2e-06
16708                                                                  49   5e-06
22804                                                                  49   5e-06
30743                                                                  45   1e-04
20152                                                                  45   1e-04
27274                                                                  43   5e-04
18996                                                                  42   7e-04
02638                                                                  42   0.001
07836                                                                  41   0.001
14477                                                                  40   0.002
08294                                                                  40   0.003
03942                                                                  40   0.003
12442                                                                  40   0.004
36305                                                                  38   0.012
11404                                                                  38   0.012
22005                                                                  38   0.013
31120                                                                  37   0.030
26304                                                                  37   0.033
13896                                                                  35   0.083
17253                                                                  35   0.093
13155                                                                  35   0.10 
29360                                                                  34   0.16 
18401                                                                  34   0.22 
23319                                                                  33   0.28 
02913                                                                  33   0.36 
17516                                                                  33   0.45 
17932                                                                  33   0.50 
01494                                                                  32   0.96 
02841                                                                  31   1.3  
26009                                                                  31   1.5  
26052                                                                  31   1.8  
13305                                                                  31   2.0  
16300                                                                  30   2.2  
18481                                                                  30   3.2  
17357                                                                  30   3.2  
33692                                                                  30   3.8  
36388                                                                  29   5.4  
17637                                                                  29   5.8  
18567                                                                  29   6.8  
00638                                                                  28   8.3  
32359                                                                  28   9.2  
>18484
          Length = 635

 Score =  289 bits (739), Expect(2) = 4e-93,   Method: Compositional matrix adjust.
 Identities = 133/161 (82%), Positives = 145/161 (90%)
 Frame = +1

Query: 424 DLMYHIQQVGKFKEPQAVFYAAEISIGLFFLHKRGIIYRDLKLDNVMLDSEGHIKIADFG 483
           DLMY IQQ GKFKEP A FYAAEI++GLFFLH +GIIYRDLKLDNVMLDSEGHIKIADFG
Sbjct: 1   DLMYRIQQEGKFKEPVAAFYAAEIAVGLFFLHDQGIIYRDLKLDNVMLDSEGHIKIADFG 180

Query: 484 MCKEHMMDGVTTRTFCGTPDYIAPEIIAYQPYGKSVDWWAYGVLLYEMLAGQPPFDGEDE 543
           MCKE M    TTRTFCGTPDYIAPEI+ YQPY KSVDWWAYGVLL+EMLAGQPPFDGEDE
Sbjct: 181 MCKEGMTGDATTRTFCGTPDYIAPEIVLYQPYSKSVDWWAYGVLLFEMLAGQPPFDGEDE 360

Query: 544 DELFQSIMEHNVSYPKSLSKEAVSICKGLMTKHPAKRLGCG 584
           DELF SI +HNVSYPK++S+EAVS+CKGL+ K+P KRLGCG
Sbjct: 361 DELFSSITDHNVSYPKAMSREAVSLCKGLLMKNPTKRLGCG 483

 Score = 72.0 bits (175), Expect(2) = 4e-93,   Method: Compositional matrix adjust.
 Identities = 32/54 (59%), Positives = 42/54 (77%), Gaps = 1/54 (1%)
 Frame = +2

Query: 581 LGCGPEGERDVREHAFFRRIDWEKLENREIQPPFKPKVCG-KGAENFDKFFTRG 633
           LG    GERD+R+HAFFRRI W+K+++ E+QPP+KPK+   + AENFDK FTR 
Sbjct: 473 LGVVQNGERDIRDHAFFRRIVWDKIKSMEVQPPYKPKITDRRKAENFDKSFTRA 634
>30755
          Length = 1137

 Score =  216 bits (549), Expect = 3e-56,   Method: Compositional matrix adjust.
 Identities = 101/215 (46%), Positives = 142/215 (66%), Gaps = 1/215 (0%)
 Frame = +2

Query: 428 HIQQVGKFKEPQAVFYAAEISIGLFFLHKRGIIYRDLKLDNVMLDSEGHIKIADFGMCKE 487
           H+     F E +  FY AEI   L +LH +GIIYRDLKL+N++LD +GHIK+ADFG+CKE
Sbjct: 2   HLSHERIFTEERTRFYGAEIISALGYLHSQGIIYRDLKLENLLLDKDGHIKVADFGLCKE 181

Query: 488 HMMDGVTTRTFCGTPDYIAPEIIAYQPYGKSVDWWAYGVLLYEMLAGQPPFDGEDEDELF 547
            +  G TT+TFCGTP+Y+APE++    YG++VDWW  GV++YEM+ G+ PF   D D LF
Sbjct: 182 DITYGRTTKTFCGTPEYLAPEVLDDNDYGRAVDWWGTGVVMYEMICGRLPFYNRDHDVLF 361

Query: 548 QSIMEHNVSYPKSLSKEAVSICKGLMTKHPAKRLGCGPEGERDVREHAFFRRIDWEKLEN 607
             I+  +V +P++++ EA S+  GL+ K P  RLG G +  ++++ H FF  I+W  L  
Sbjct: 362 TLILVEDVKFPRNITDEAKSLLSGLLAKDPRNRLGGGQDDVKEIQAHPFFASINWTDLVQ 541

Query: 608 REIQPPFKPKVCG-KGAENFDKFFTRGQPVLTPPD 641
           ++I PPFKP+V        FD+ FT     LTPPD
Sbjct: 542 KKITPPFKPQVTSDTDTRYFDEEFTGESVELTPPD 646
>18663
          Length = 600

 Score =  179 bits (453), Expect = 5e-45,   Method: Compositional matrix adjust.
 Identities = 96/177 (54%), Positives = 118/177 (66%), Gaps = 12/177 (6%)
 Frame = +2

Query: 497 TFCGTPDYIAPEIIAYQPYGKSVDWWAYGVLLYEMLAGQPPF---------DGEDEDELF 547
           TFCGTP+YIAPEI+  + YG SVDWWA GVLLYEMLAG+ PF         D   ED LF
Sbjct: 5   TFCGTPNYIAPEILRGEDYGFSVDWWALGVLLYEMLAGRSPFDIAGASENPDQNTEDYLF 184

Query: 548 QSIMEHNVSYPKSLSKEAVSICKGLMTKHPAKRLGCGPEGE-RDVREHAFFRRIDWEKLE 606
           Q I+E  +  P+SLS +A S+ KG + K+PA RLGC  E    D+  H FF+ IDWE LE
Sbjct: 185 QVILEKTIRIPRSLSVKAASVLKGFLNKNPADRLGCHRESAFMDIVNHPFFKVIDWEMLE 364

Query: 607 NREIQPPFKPKV-CGKGAENFDKFFTRGQPV-LTPPDQLVIANIDQSDFEGFSYVNP 661
            +++ PPFKP++   +   NF   FT G+PV LTP D  VI +IDQS+FEGF YVNP
Sbjct: 365 RKQVSPPFKPRLDSDRDLANFPIEFT-GEPVQLTPDDDHVIDSIDQSEFEGFEYVNP 532
>25445
          Length = 460

 Score =  175 bits (444), Expect = 4e-44,   Method: Compositional matrix adjust.
 Identities = 91/154 (59%), Positives = 109/154 (70%), Gaps = 4/154 (2%)
 Frame = -1

Query: 80  EFVTFSCPGADKGPDTDDPRSKHKFKIHTYGSPTFCDHCGSLLYGLIHQGMKCDTCDMNV 139
           EFV+F+CPGAD GPD+D   + HKFK HTYGSPTFCDHCGSLLYGLIHQG+KCD+CDMN 
Sbjct: 460 EFVSFACPGADNGPDSDA-TNLHKFKAHTYGSPTFCDHCGSLLYGLIHQGLKCDSCDMNC 284

Query: 140 HKQCVINVPSLCGMDHTEKRGRIYLKAEVTDEKLHVTVRDAKN----LIPMDPNGLSDPY 195
           HK+C  +VP LCGMDHTE+RGRIYL+      KL V V++AK      I M    L    
Sbjct: 283 HKRCEKHVPRLCGMDHTERRGRIYLRISPHGSKLLVNVKEAKKPCVPWIQMVWPILIPK* 104

Query: 196 VKLKLIPDPKNESKQKTKTIRSTLNPQWNESFTF 229
               +IP  + E    TKTI+S+LNPQW+E+FT 
Sbjct: 103 S*FHMIPTKQTE----TKTIKSSLNPQWDETFTL 14

 Score = 52.4 bits (124), Expect = 6e-07,   Method: Compositional matrix adjust.
 Identities = 31/92 (33%), Positives = 41/92 (44%)
 Frame = -1

Query: 20  FARKGALRQKNVHEVKDHKFIARFFKQPTFCSHCTDFIWGFGKQGFQCQVCCFVVHKRCH 79
           FA  GA    +      HKF A  +  PTFC HC   ++G   QG +C  C    HKRC 
Sbjct: 448 FACPGADNGPDSDATNLHKFKAHTYGSPTFCDHCGSLLYGLIHQGLKCDSCDMNCHKRCE 269

Query: 80  EFVTFSCPGADKGPDTDDPRSKHKFKIHTYGS 111
           + V   C     G D  + R +   +I  +GS
Sbjct: 268 KHVPRLC-----GMDHTERRGRIYLRISPHGS 188
>03240
          Length = 1683

 Score =  164 bits (416), Expect = 7e-41,   Method: Compositional matrix adjust.
 Identities = 118/387 (30%), Positives = 181/387 (46%), Gaps = 59/387 (15%)
 Frame = -3

Query: 300  ELRQKFEKAKLGPAGNKVISPSEDRKQPSN-NLDRVKLTD--FNFLMVLGKGSFGKVMLA 356
            +L  +  K KL     + +     +K+ +   L R K+    F  +  LG G+FG+V L 
Sbjct: 1411 QLENEMAKVKLSEEAARQMRRMLHQKESNYIRLKRAKMDKCMFEKIKTLGVGAFGEVSLC 1232

Query: 357  DRKGTEELYAIKILKKDVVIQDDDVECTMVEKRVLALLDKPPFLTQLHSCFQTVDRLYFV 416
             +  T  LYA+K L+K  V++ + V     E+ +LA  D   ++ +L+  FQ  + LYFV
Sbjct: 1231 RKNDTGMLYAMKTLRKSDVLKRNQVAHVKAERDILAEADNE-WVVKLYYSFQDHNYLYFV 1055

Query: 417  MEYVNGGDLMYHIQQVGKFKEPQAVFYAAEISIGLFFLHKRGIIYRDLKLDNVMLDSEGH 476
            M+YV GGDLM  + ++    EP A FY AE+   +  +H+ G I+RD+K DN+++D  GH
Sbjct: 1054 MDYVPGGDLMGLLIRMEILDEPLARFYVAELVQAIESVHRMGFIHRDIKPDNILIDRNGH 875

Query: 477  IKIADFGMC---------KEHMMDGVTTR------------------------------- 496
            IK+ DFG+C         K +  DG   R                               
Sbjct: 874  IKLTDFGLCTGFRWTHNSKYYQRDGTHARQDSMEVKCQLDEQCQCEILKPLERRRKREQR 695

Query: 497  ----TFCGTPDYIAPEIIA-YQPYGKSVDWWAYGVLLYEMLAGQPPFDGEDEDELFQSIM 551
                +  GTP+YIAPE+++    Y    DWW+ GV+L+EML G PPF      E    ++
Sbjct: 694  CLAHSLVGTPNYIAPEVLSRLGGYTSVCDWWSVGVILFEMLVGHPPFYANTPAETQYKVI 515

Query: 552  EHNVSYPKSLSKEAVSICKGLMTKHPAK----RLGCGPE------GERDVREHAFFRRID 601
                       K+ + I +      PAK    RL CG +      G  +++ H FF  ++
Sbjct: 514  NW---------KDMLKIPRESNLSQPAKDLILRLCCGSDDRLGLNGAGEIKTHMFFAGVN 362

Query: 602  WEKLENREIQPPFKPKV-CGKGAENFD 627
            +E L  R+ QPP+ P +       NFD
Sbjct: 361  FETL--RKQQPPYVPNIRYATDTSNFD 287
>00486
          Length = 797

 Score =  148 bits (373), Expect = 8e-36,   Method: Compositional matrix adjust.
 Identities = 69/174 (39%), Positives = 106/174 (60%), Gaps = 1/174 (0%)
 Frame = -2

Query: 495 TRTFCGTPDYIAPEIIAYQPYGKSVDWWAYGVLLYEMLAGQPPFDGEDEDELFQSIMEHN 554
           T TFCGT +Y+APEI+    +GK+VDWW+ G L+Y+ML G PPF  E+  +    I++  
Sbjct: 787 THTFCGTIEYMAPEILTRTGHGKAVDWWSLGALMYDMLTGSPPFTAENRKKTIDKILKGK 608

Query: 555 VSYPKSLSKEAVSICKGLMTKHPAKRLGCGPEGERDVREHAFFRRIDWEKLENREIQPPF 614
           ++ P  L+ EA  + K L+ K+PA+RLG G +    +++H FFR  +W  L  R  +PPF
Sbjct: 607 LNLPPYLTNEARGLIKKLLRKNPAERLGGGHDDSGPIKDHQFFRNTNWALLALRRAEPPF 428

Query: 615 KPKVCG-KGAENFDKFFTRGQPVLTPPDQLVIANIDQSDFEGFSYVNPQFVHPI 667
           +P V   +    FD  FTR  PV +P D ++  +I+Q  F+GF+Y+ P  +  +
Sbjct: 427 RPNVTSDEDTSQFDTKFTRQTPVDSPDDTILSDSINQV-FKGFTYIAPSVLEEV 269
>26156
          Length = 479

 Score =  109 bits (273), Expect(2) = 1e-31,   Method: Compositional matrix adjust.
 Identities = 50/111 (45%), Positives = 76/111 (68%)
 Frame = -1

Query: 332 DRVKLTDFNFLMVLGKGSFGKVMLADRKGTEELYAIKILKKDVVIQDDDVECTMVEKRVL 391
           +++ LTDF  L V+G+GS+ KV+  + K T+ +YA+K++KK++V  D+D++    EK V 
Sbjct: 404 NKLGLTDFLLLRVIGRGSYAKVLQVEHKRTKRIYAMKVIKKELVNDDEDIDWVQTEKHVF 225

Query: 392 ALLDKPPFLTQLHSCFQTVDRLYFVMEYVNGGDLMYHIQQVGKFKEPQAVF 442
                 PFL  LHSCFQ+  RL+FV+E+VNGGDLM+H+Q+  +  E  A F
Sbjct: 224 ETATNYPFLVGLHSCFQSESRLFFVIEFVNGGDLMFHMQRQRRLPEEHARF 72

 Score = 45.8 bits (107), Expect(2) = 1e-31,   Method: Composition-based stats.
 Identities = 19/25 (76%), Positives = 22/25 (88%)
 Frame = -3

Query: 442 FYAAEISIGLFFLHKRGIIYRDLKL 466
           FY+AEI + L FLHKRGI+YRDLKL
Sbjct: 75  FYSAEICLALNFLHKRGIVYRDLKL 1
>27405
          Length = 532

 Score =  117 bits (292), Expect = 2e-26,   Method: Compositional matrix adjust.
 Identities = 63/178 (35%), Positives = 101/178 (56%), Gaps = 4/178 (2%)
 Frame = -3

Query: 349 SFGKVMLADRKGTEELYAIKILKKDVVIQDDDVECTMVEKRVLALL---DKPPFLTQLHS 405
            FG+V    +  T ++YA+K L K  +         + E+ +L+L+   +  PF+  +  
Sbjct: 530 GFGEVYGCRKADTGKMYAMKCLDKKRIKMKGGETLALNERIMLSLVSTGEGSPFIVCMTY 351

Query: 406 CFQTVDRLYFVMEYVNGGDLMYHIQQVGKFKEPQAVFYAAEISIGLFFLHKRGIIYRDLK 465
            FQT ++L F+++ +NGGDL YH+ Q G F E +  FYAAE+ +GL  +H R ++YRDLK
Sbjct: 350 AFQTPEKLCFILDLMNGGDLHYHLSQHGVFTEKEVRFYAAEVMLGLEHMHSRFVVYRDLK 171

Query: 466 LDNVMLDSEGHIKIADFGMCKEHMMDGVTTRTFCGTPDYIAPEIIAY-QPYGKSVDWW 522
             N++LD  GH++I+D G+  +            GT  Y+APE++   Q Y  S DW+
Sbjct: 170 PANILLDENGHVRISDLGLACD--FSKKKPHASVGTHGYMAPEVLMKGQAYDSSADWF 3
>25019
          Length = 730

 Score = 79.7 bits (195), Expect(2) = 2e-25,   Method: Compositional matrix adjust.
 Identities = 31/59 (52%), Positives = 44/59 (74%)
 Frame = +3

Query: 467 DNVMLDSEGHIKIADFGMCKEHMMDGVTTRTFCGTPDYIAPEIIAYQPYGKSVDWWAYG 525
           +NV+LD +GH+K+ DFG+CKE +     T TFCGT +Y+APEI+    +GK+VDWW+ G
Sbjct: 261 ENVLLDKDGHVKLTDFGLCKEAITGTRVTHTFCGTIEYMAPEILTRTGHGKAVDWWSLG 437

 Score = 55.1 bits (131), Expect(2) = 2e-25,   Method: Compositional matrix adjust.
 Identities = 23/59 (38%), Positives = 37/59 (62%)
 Frame = +1

Query: 524 YGVLLYEMLAGQPPFDGEDEDELFQSIMEHNVSYPKSLSKEAVSICKGLMTKHPAKRLG 582
           +G L+Y+ML G PPF  E+  +    I++  ++ P  L+ EA  + K L+ K+PA+RLG
Sbjct: 433 WGALMYDMLTGSPPFTAENRKKTIDKILKGKLNLPPYLTNEARGLIKKLLRKNPAERLG 609
>12721
          Length = 821

 Score =  110 bits (276), Expect = 1e-24,   Method: Compositional matrix adjust.
 Identities = 72/240 (30%), Positives = 121/240 (50%), Gaps = 1/240 (0%)
 Frame = +1

Query: 303 QKFEKAKLGPAGNKVISPSEDRKQPSNNLDRVKLTDFNFLMVLGKGSFGKVMLADRKGTE 362
           Q+    +   A   V++P + R           L DF   M +G+GS G V +A  +   
Sbjct: 22  QRLSHEQFRAALQMVVTPGDPR---------TFLDDF---MKIGEGSTGIVCIATSRDGR 165

Query: 363 ELYAIKILKKDVVIQDDDVECTMVEKRVLALLD-KPPFLTQLHSCFQTVDRLYFVMEYVN 421
           ++ A+K  K D+  Q       ++   V+ + D   P + ++++ +   D L+ VME++ 
Sbjct: 166 QM-AVK--KMDLRKQQ---RRELLFNEVVVMRDYHHPNIVEMYNSYLVNDELWVVMEFME 327

Query: 422 GGDLMYHIQQVGKFKEPQAVFYAAEISIGLFFLHKRGIIYRDLKLDNVMLDSEGHIKIAD 481
           GG L   I    +  E Q           L FLH  G+I+RD+K D+++L  +G +K+ D
Sbjct: 328 GGAL-TDIVTNNRMDEVQIATVCRACLKALAFLHANGVIHRDIKSDSILLSHDGKVKLXD 504

Query: 482 FGMCKEHMMDGVTTRTFCGTPDYIAPEIIAYQPYGKSVDWWAYGVLLYEMLAGQPPFDGE 541
           FG C +   D    ++  GTP ++APE+I+  PYG  VD W+ G+++ EM+  +PPF  E
Sbjct: 505 FGFCAQVTQDLQKRKSLVGTPYWMAPEVISRLPYGPEVDIWSLGIMVMEMIDAEPPFFNE 684
>31885
          Length = 529

 Score =  107 bits (266), Expect = 2e-23,   Method: Compositional matrix adjust.
 Identities = 56/146 (38%), Positives = 85/146 (58%), Gaps = 5/146 (3%)
 Frame = -2

Query: 398 PFLTQLHSCFQTVDRLYFVMEYVNGGDLMYHIQQVGKFKEPQAVFYAAEISIGLFFLHKR 457
           PFL  L   FQ  + L+ V++   GGDL YH+QQ   F+E    FY  ++++ L +L  +
Sbjct: 492 PFLVNLWYAFQDEEDLFMVVDLFLGGDLRYHMQQEVSFREDCVKFYLCQLALVLDYLRSQ 313

Query: 458 GIIYRDLKLDNVMLDSEGHIKIADFGMCKEHMMDGVTTRTFCGTPDYIAPEIIAY----- 512
            I++RD+K DN++LD +GH  + DF +  +   D + T T  GT  Y+APE+        
Sbjct: 312 KIVHRDIKPDNILLDEQGHCHVTDFNIATQLEDDELATST-SGTRPYMAPEVYGVAINER 136

Query: 513 QPYGKSVDWWAYGVLLYEMLAGQPPF 538
           + YG  VDWW+ GV L+E+L  + PF
Sbjct: 135 RGYGFPVDWWSLGVSLFELLKKRRPF 58
>26560
          Length = 398

 Score =  102 bits (255), Expect = 4e-22,   Method: Compositional matrix adjust.
 Identities = 48/123 (39%), Positives = 74/123 (60%), Gaps = 1/123 (0%)
 Frame = -1

Query: 424 DLMYHIQQVGKFKEPQAVFYAAEISIGLFFLHKRGIIYRDLKLDNVMLDSEGHIKIADFG 483
           DL YH+ Q G F E +  FYAAE+ +GL  +H R ++YRDLK  N++LD  GH++I+D G
Sbjct: 398 DLHYHLSQHGVFTEKEVRFYAAEVMLGLEHMHSRFVVYRDLKPANILLDENGHVRISDLG 219

Query: 484 MCKEHMMDGVTTRTFCGTPDYIAPEIIAY-QPYGKSVDWWAYGVLLYEMLAGQPPFDGED 542
           +  +            GT  Y+APE++   Q Y  S DW+++G +LY++L G  PF   +
Sbjct: 218 LACD--FSKKRPHASVGTHGYMAPEVLMKGQSYDSSADWFSFGCMLYKLLKGHSPFRQHN 45

Query: 543 EDE 545
           + +
Sbjct: 44  QGQ 36
>09606
          Length = 1300

 Score =  101 bits (252), Expect = 9e-22,   Method: Compositional matrix adjust.
 Identities = 79/298 (26%), Positives = 125/298 (41%), Gaps = 33/298 (11%)
 Frame = -3

Query: 334  VKLTDFNFLMVLGKGSFGKVMLADRKGTEELYAIKILKKDVVIQDDDVECTMVEKRVLAL 393
             ++ +F     LGKG    +    RKGT    AI  ++K    +  +V  T+     ++ 
Sbjct: 1124 TRMENFVLYEELGKGEHSIIYKGRRKGTINFVAIHCIEK---CKRPEVTNTVRMTHDIS- 957

Query: 394  LDKPPFLTQLHSCFQTVDRLYFVMEYVNGGDLMYHIQQVGKFKEPQAVFYAAEISIGLFF 453
                P + Q H  ++T + L+ V+E   GG L   + Q     E     +   +  GL +
Sbjct: 956  ---HPNVVQFHEWYETSNHLWLVVELCTGGSLADILAQDHHLPETSIRDFGIHLVTGLHY 786

Query: 454  LHKRGIIYRDLKLDNVMLDSEGHIKIADFGMCK-------------------------EH 488
            +H  GI++ DL+   V+LD+ G +K ADFG+ K                         E 
Sbjct: 785  IHSLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEAGDQWNIQSAEE 606

Query: 489  MMDGVTTRTFCGTPDYIAPEIIAYQPYGKSVDWWAYGVLLYEMLAGQPPFDGEDEDELFQ 548
            MM  V T    G+P Y+APE+          D WA G + YEM +G PPF GE  D    
Sbjct: 605  MMKQVPT---SGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFSGHPPFLGETYDITKD 435

Query: 549  SIMEHNVSYPK--------SLSKEAVSICKGLMTKHPAKRLGCGPEGERDVREHAFFR 598
             ++      PK          S E +++ + L+ K   +RL         + +HAF++
Sbjct: 434  KVLNKEFPLPKVKGSRLSAKPSPEFLNLLESLLQKDSTRRLSWA-----SLVKHAFWQ 276
>17722
          Length = 680

 Score = 99.8 bits (247), Expect = 4e-21,   Method: Compositional matrix adjust.
 Identities = 43/100 (43%), Positives = 67/100 (67%)
 Frame = -3

Query: 519 VDWWAYGVLLYEMLAGQPPFDGEDEDELFQSIMEHNVSYPKSLSKEAVSICKGLMTKHPA 578
           VDWW  GV++YEM+ G+ PF   D D LF+ I+  NV +P++LS+EA ++  GL+ K+P 
Sbjct: 678 VDWWGTGVVMYEMMCGRLPFYNRDHDVLFELILLQNVKFPRNLSEEAKTLLSGLLAKNPK 499

Query: 579 KRLGCGPEGERDVREHAFFRRIDWEKLENREIQPPFKPKV 618
           +RLG       +++ H FF+ I+W+ L  ++I PP+KP V
Sbjct: 498 RRLGGSEADVTEIKTHPFFQCINWDDLAAKKITPPWKPDV 379
>13066
          Length = 551

 Score = 99.4 bits (246), Expect = 5e-21,   Method: Compositional matrix adjust.
 Identities = 57/160 (35%), Positives = 87/160 (54%), Gaps = 9/160 (5%)
 Frame = +3

Query: 375 VIQDDDVECTMVEK---RVLALLDK--PPFLTQLHSCFQTVDRLYFVMEYVNGGDLMYHI 429
           +I  +      VEK   R L LL K   P++ Q+HS  Q   + +  M +   GDL+ +I
Sbjct: 72  IIDKEKAPVDFVEKFFPRELDLLTKLDHPYIIQIHSILQRXPKNFIFMRFAERGDLLTYI 251

Query: 430 QQVGKFKEPQAVFYAAEISIGLFFLHKRGIIYRDLKLDNVMLDSEGHIKIADFGM---CK 486
           Q+VG  KE QA  +  +++  L +LH   + +RDLK +N++L S  ++K+ADFG    C 
Sbjct: 252 QEVGFVKEKQAKIWFYQMTTALNYLHSYDVAHRDLKCENILLSSHFNVKLADFGFACACI 431

Query: 487 EHMMDGVTTRTFCGTPDYIAPEIIAYQPYG-KSVDWWAYG 525
               +   +RT+CG+  Y APEI+   PY  K  D W+ G
Sbjct: 432 TESGEKYMSRTYCGSAAYAAPEIVYGAPYAPKVADAWSLG 551
>14420
          Length = 528

 Score = 99.4 bits (246), Expect = 5e-21,   Method: Compositional matrix adjust.
 Identities = 48/148 (32%), Positives = 81/148 (54%)
 Frame = +2

Query: 395 DKPPFLTQLHSCFQTVDRLYFVMEYVNGGDLMYHIQQVGKFKEPQAVFYAAEISIGLFFL 454
           ++ P +      +   + L+ VME++ GG L   + +     E Q      E    L FL
Sbjct: 71  NQNPNIVNYLDSYLVGEELWVVMEFLAGGSLTDVVTETC-MDEGQIAAVCRECLQALEFL 247

Query: 455 HKRGIIYRDLKLDNVMLDSEGHIKIADFGMCKEHMMDGVTTRTFCGTPDYIAPEIIAYQP 514
           H+  +I+RD+K DN++L  +G +K+ DFG C +   +     T  GTP ++APE++  + 
Sbjct: 248 HENQVIHRDIKSDNILLGMDGSVKLTDFGFCAQLSPEQSKRSTMVGTPYWMAPEVVTRKQ 427

Query: 515 YGKSVDWWAYGVLLYEMLAGQPPFDGED 542
           YG +VD W+ GV+  EM+ G+PP+  E+
Sbjct: 428 YGPTVDIWSLGVMCIEMIEGEPPYLNEN 511
>18921
          Length = 697

 Score = 98.6 bits (244), Expect = 7e-21,   Method: Compositional matrix adjust.
 Identities = 69/203 (33%), Positives = 105/203 (51%), Gaps = 4/203 (1%)
 Frame = +2

Query: 339 FNFLMVLGKGSFGKVMLADRKGTEELYAIKILKKDVVIQDDDVECTMVEKRVLALLDKPP 398
           F+ L  LG+GS+G V  +  K T ++ AIK      V  D D++  + E  ++   D   
Sbjct: 35  FDILGKLGEGSYGSVFKSLHKETGQVLAIK-----QVPVDTDLQEIIKEISIMQQCDSKY 199

Query: 399 FLTQLHSCFQTVDRLYFVMEYVNGG---DLMYHIQQVGKFKEPQAVFYAAEISIGLFFLH 455
            +    S F+  D L+ VMEY   G   D+M    +    +E   + Y      GL +LH
Sbjct: 200 IVKYYGSYFKNTD-LWIVMEYCGAGSVSDIMRLRNKTLVEREIATILYYT--LKGLXYLH 370

Query: 456 KRGIIYRDLKLDNVMLDSEGHIKIADFGMCKEHMMDGVTTR-TFCGTPDYIAPEIIAYQP 514
            R  I+RD+K  N++L++EGH K+ADFG+  + + D +  R T  GTP ++APE+I    
Sbjct: 371 SRRKIHRDIKAGNILLNNEGHAKLADFGVAGQ-LTDTMAKRNTVIGTPYWMAPEVIQEIG 547

Query: 515 YGKSVDWWAYGVLLYEMLAGQPP 537
           Y    D W+ G+   EM  G+PP
Sbjct: 548 YDCVADIWSLGITALEMAEGKPP 616
>06405
          Length = 1965

 Score = 95.9 bits (237), Expect = 5e-20,   Method: Compositional matrix adjust.
 Identities = 66/235 (28%), Positives = 114/235 (48%), Gaps = 4/235 (1%)
 Frame = +1

Query: 318 ISPSEDRKQPSNNLDRVKLTDFNFLMVLGKGSFGKVMLADRKGTEELYAIKILKKDVVIQ 377
           +SP  DR +       ++ T+      LG G +G V  A  K   ++ A+K LK+D +  
Sbjct: 223 VSPEPDRWE-------IERTEIAMKHRLGGGQYGDVYEAMWKRYNKIVAVKTLKEDTMAL 381

Query: 378 DDDVECTMVEKRVLALLDKPPFLTQLHSCFQTVDRLYFVMEYVNGGDLMYHIQQVGKFKE 437
           +D +E   + K +     K P L QL          Y V E++  G+L+ +++   + + 
Sbjct: 382 NDFLEEAAIMKEM-----KHPNLVQLLGVCTREPPFYIVTEFMPHGNLLDYLRSSTREEN 546

Query: 438 -PQAVFY-AAEISIGLFFLHKRGIIYRDLKLDNVMLDSEGHIKIADFGMCKEHMMDGVTT 495
            P A+ Y A +I+ G+ +L  +  I+RDL   N ++     +K+ADFG+ +    D  T 
Sbjct: 547 GPTALMYMATQIASGMAYLETKNFIHRDLAARNCLVADSNMVKVADFGLARLMKDDTYTA 726

Query: 496 RTFCGTP-DYIAPEIIAYQPYGKSVDWWAYGVLLYEMLA-GQPPFDGEDEDELFQ 548
                 P  + APE +A+  +    D WA+GVLL+E+   G  P+ G +  E++ 
Sbjct: 727 HIGAKFPIKWTAPEGLAFNRFSTRSDIWAFGVLLWELATYGMSPYPGVELTEVYH 891
>15910
          Length = 1361

 Score = 94.0 bits (232), Expect = 2e-19,   Method: Compositional matrix adjust.
 Identities = 53/165 (32%), Positives = 91/165 (55%), Gaps = 7/165 (4%)
 Frame = +2

Query: 424 DLMYHIQQVGKFKEPQAVFYAAEISIGLFFLHKRGIIYRDLKLDNVM---LDSEGHIKIA 480
           +L   I   G++ E  A    ++I  G+ ++H  G+++RDLK +N++   +  +  +K+A
Sbjct: 422 ELFDRIVTRGQYTEKDAARAISDILHGVQYIHANGVVHRDLKPENLLYECMTDDSKLKLA 601

Query: 481 DFGMCKEHMMDGVTTRTFCGTPDYIAPEIIAYQPYGKSVDWWAYGVLLYEMLAGQPPFDG 540
           DFG+ +  +   V   T CGTP Y APE++    Y  SVD W+ GV+ Y +L G  PF  
Sbjct: 602 DFGLSR-IIEPEVQMSTVCGTPGYCAPEVLKGDKYTPSVDMWSVGVIAYILLCGYEPFFA 778

Query: 541 EDEDELFQSIM----EHNVSYPKSLSKEAVSICKGLMTKHPAKRL 581
           E+E E+++ I+    + +  Y   +S+ A  + + L+   P KRL
Sbjct: 779 ENEFEMYRKIIKGEYKFDEEYWSEISENAKDVVRKLLVIDPKKRL 913
>00300
          Length = 2318

 Score = 94.0 bits (232), Expect = 2e-19,   Method: Compositional matrix adjust.
 Identities = 71/248 (28%), Positives = 116/248 (46%), Gaps = 12/248 (4%)
 Frame = -1

Query: 345  LGKGSFGKVMLADRKGTEELYAIKILKKDVVIQDDDVECT--MVEKRVLALLDKPPFLTQ 402
            +G+G FGKV  A    T EL A+K +K     Q +D++    M ++  +    +   L +
Sbjct: 1634 IGEGQFGKVYTAVNMSTGELMALKEMK----FQPNDLQQLREMCDEIKIFEGIQHENLVK 1467

Query: 403  LHSCFQTVDRLYFVMEYVNGGDLMYHIQQVGKFKEPQAVF--YAAEISIGLFFLHKRGII 460
             +      D +   MEY + G     I++  K   P+ +   Y  EI + +  LH+  I+
Sbjct: 1466 YYGVEVHKDEMLMFMEYCDTGT----IEEAAKMGLPEYLIRRYTREIVLAVNHLHENSIV 1299

Query: 461  YRDLKLDNVMLDSEGHIKIADFG---MCKEHMMDGVTTRTFCGTPDYIAPEIIAYQP--- 514
            +RD+K  N+ L S GH+K+ DFG     K H           GT  Y+APE+        
Sbjct: 1298 HRDIKGANIFLTSNGHVKLGDFGCSVKLKSHTTMPGEFHNLVGTTAYMAPEVFTQNDQGG 1119

Query: 515  YGKSVDWWAYGVLLYEMLAGQPPFDGEDEDE--LFQSIMEHNVSYPKSLSKEAVSICKGL 572
            YG++ D W+ G ++ EM  G+ P+   D +   +++  + H  + P SLS E       +
Sbjct: 1118 YGRAADIWSLGCVVIEMATGKRPWHDLDNNYQIMYKVGIGHKPAVPDSLSVEGKHFLDLI 939

Query: 573  MTKHPAKR 580
            M   PA+R
Sbjct: 938  MCHDPAQR 915
>13592
          Length = 980

 Score = 86.3 bits (212), Expect = 4e-17,   Method: Compositional matrix adjust.
 Identities = 68/248 (27%), Positives = 113/248 (45%), Gaps = 11/248 (4%)
 Frame = +2

Query: 345 LGKGSFGKVMLADRKGTEELYAIKILKKDVVIQDDDVECTMVEKRVLALLD--KPPFLTQ 402
           +G+G FGKV  A    T EL A+K    ++ IQ  +          L +L+  K   L +
Sbjct: 8   IGQGRFGKVYTAVNNNTGELMAMK----EIAIQPGETRALKNVAEELKILEGIKHKNLVR 175

Query: 403 LHSCFQTVDRLYFVMEYVNGGDLMYHIQQVGKFKEPQAVFYAAEISIGLFFLHKRGIIYR 462
            +      + L   ME  + G L   ++  G   E  +  + A++  G+  LHK GI++R
Sbjct: 176 YYGIEVHREELLIFMELCSEGTLESLVELTGGLPEALSRRFTAQLLSGVAELHKHGIVHR 355

Query: 463 DLKLDNVML-DSEGHIKIADFGMC---KEHMMDGVTTRTFCGTPDYIAPEIIA---YQPY 515
           D+K  N+ L D    +K+ DFG     + H       + + GT  Y+APE+        +
Sbjct: 356 DIKTANIFLVDGSNSLKLGDFGSAVKIQAHTTVPGELQGYVGTQAYMAPEVFTKTNSDGH 535

Query: 516 GKSVDWWAYGVLLYEMLAGQPPFDGEDED--ELFQSIMEHNVSYPKSLSKEAVSICKGLM 573
           G+  D W+ G ++ EM +G+ P+   D +   +F+  M      P+SLS+E        +
Sbjct: 536 GRLADIWSVGCVVVEMASGKRPWAQFDSNFQIMFKVGMGEKPQAPESLSQEGHDFIDHCL 715

Query: 574 TKHPAKRL 581
              P +RL
Sbjct: 716 QHDPKQRL 739
>01707
          Length = 757

 Score = 84.7 bits (208), Expect = 1e-16,   Method: Compositional matrix adjust.
 Identities = 69/220 (31%), Positives = 108/220 (49%), Gaps = 5/220 (2%)
 Frame = +1

Query: 332 DRV-KLTDFNFLMVLGKGSFGKVMLADRKGTEELYAIKILKKDVVIQDDDV--ECTMVEK 388
           DRV ++  +  +  +G+GS+G V     K T +L AIK   K V  +DD +  +  M E 
Sbjct: 46  DRVDRMEKYEKIGKIGEGSYGVVFKCRNKETSQLVAIK---KFVESEDDPLIKKIAMREI 216

Query: 389 RVLALLDKPPFLTQLHSCFQTVDRLYFVMEYVNGGDLMYHIQQVGKFKEPQAVFYAAEIS 448
           R+L  L K P L +L   F+   RL+ V +YV+   L    +      EP       +  
Sbjct: 217 RMLKQL-KHPNLVRLIEVFRRKKRLHLVFDYVDHTLLNELDRYPRGLPEPMVKRIIYQTL 393

Query: 449 IGLFFLHKRGIIYRDLKLDNVMLDSEGHIKIADFGMCKEHMMDGVTTRTFCGTPDYIAPE 508
           + + F H+   I+RD+K +N+++  +G +K+ DFG  +     G     +  T  Y APE
Sbjct: 394 LAVNFCHQYNTIHRDVKPENILITRQGQVKLCDFGFARILTGPGDEYTDYVATRWYRAPE 573

Query: 509 -IIAYQPYGKSVDWWAYGVLLYEMLAGQPPFDGE-DEDEL 546
            ++    YG  VD WA G +  E+L GQ  + G  D D+L
Sbjct: 574 LLVGDTQYGPPVDVWAIGCVFAELLTGQALWPGRSDVDQL 693
>01392
          Length = 1806

 Score = 82.4 bits (202), Expect = 6e-16,   Method: Compositional matrix adjust.
 Identities = 65/218 (29%), Positives = 94/218 (43%), Gaps = 43/218 (19%)
 Frame = -1

Query: 433  GKFKEPQAVFYAAEISIGLFFLHKRGIIYRDLKLDNVM---LDSEGHIKIADFGMCKEHM 489
            G   E +A      I+  L FLH +GI +RDLK +N++   LD    +KI DF +     
Sbjct: 1806 GHLCEREASLVVRHIARALDFLHSKGIAHRDLKPENILCEHLDDVVPVKICDFDLASGIS 1627

Query: 490  MDGVTTRTF-----CGTPDYIAPEIIAYQ-----PYGKSVDWWAYGVLLYEMLAGQPPF- 538
             DG  T+T       G+ +Y+APE++         Y K  D W+ G++LY ML G PPF 
Sbjct: 1626 CDGDGTKTPELLTPVGSAEYMAPEVVDAWVGDSFSYDKRCDLWSLGIILYIMLCGYPPFY 1447

Query: 539  --DGED------------EDELFQSIMEHNVSYPK----SLSKEAVSICKGLMTKHPAKR 580
               GED            +D LF SI + +  +P     S+S  A  + + L+ + P KR
Sbjct: 1446 GQCGEDCGWNRGEACHDCQDMLFNSIQDGHYKFPSQEWTSISSSAKDLIRHLLVREPRKR 1267

Query: 581  LGCG-----------PEGERDVREHAFFRRIDWEKLEN 607
                           P   +    H   R    + LEN
Sbjct: 1266 YSAADVLKHPWICTPPAATQLATPHVLTRNNSMKDLEN 1153
>21808
          Length = 1011

 Score = 80.5 bits (197), Expect = 2e-15,   Method: Compositional matrix adjust.
 Identities = 54/196 (27%), Positives = 92/196 (46%), Gaps = 3/196 (1%)
 Frame = +1

Query: 366 AIKILKKDVVIQDDDVECTMVEKRVLALLDKPPFLTQLHSCFQTVDRLYFVMEYVNGGDL 425
           AIK LK   +   D +    + K++     + P L QL++     D ++ + E +  G L
Sbjct: 31  AIKTLKSGTMDPKDFLAEAQIMKKL-----RHPKLIQLYAVCTQDDPIFIITELMKNGSL 195

Query: 426 MYHIQQVGK-FKEPQAVFYAAEISIGLFFLHKRGIIYRDLKLDNVMLDSEGHIKIADFGM 484
           +  +Q  G+  K P  +   A+I+ G+ +L  +  I+RDL   N+++     +KIADFG+
Sbjct: 196 LEFLQGKGRVLKLPALIDIGAQIACGMAYLESQNYIHRDLAARNILVSDNNTVKIADFGL 375

Query: 485 CKEHMMDGVTTRTFCGTP-DYIAPEIIAYQPYGKSVDWWAYGVLLYEMLA-GQPPFDGED 542
            +    D    R     P  + APE   Y  +    D W++G+LL E +  G+ P+ G  
Sbjct: 376 ARVIKEDEYEARVGARFPIKWTAPEAANYNRFTIKSDVWSFGILLTETVTYGRVPYPGMT 555

Query: 543 EDELFQSIMEHNVSYP 558
             E+   + EH    P
Sbjct: 556 NAEVLHQV-EHGYRMP 600
>01060
          Length = 1800

 Score = 79.7 bits (195), Expect = 3e-15,   Method: Compositional matrix adjust.
 Identities = 65/221 (29%), Positives = 104/221 (47%), Gaps = 8/221 (3%)
 Frame = +1

Query: 336 LTDFNFLMVLGKGSFGKVMLADRKGTEELYAIKILKKDVVIQDDDVECTMVEKRVLALLD 395
           LTDF     +G+G++G V     + T    A+K  K  +   +D V  + + +  +    
Sbjct: 79  LTDFQ---KIGEGTYGVVYKCRHRATGRKLAMK--KIRLRGSEDGVPSSAIREIAMLREL 243

Query: 396 KPPFLTQLHSCFQTVDRLYFVMEYVNGGDLMYHIQQVGKFKEPQAV------FYAAEISI 449
           +   +  L       +RL+ V E+++    MY    + KF E   +       Y  +I  
Sbjct: 244 RHTNIVCLEDVIMEDERLFLVFEFLSMDLKMY----IDKFPEGVVLDRRLVKSYVFQIVT 411

Query: 450 GLFFLHKRGIIYRDLKLDNVMLDSEGHIKIADFGMCKEHMMDGVTTRTFCGTPDYIAPEI 509
           G+ F H+R I++RDLK  N++++  G IKIADFGM +   +          T  Y APEI
Sbjct: 412 GIXFCHQRRIVHRDLKPQNLLINHTGAIKIADFGMARTFALPVRAYTHEVVTLWYRAPEI 591

Query: 510 I-AYQPYGKSVDWWAYGVLLYEMLAGQPPFDGEDE-DELFQ 548
           +     Y   VD W+ G +  +ML   P F G+ E D+LF+
Sbjct: 592 LMGASKYSTPVDVWSIGTIFADMLIRTPIFKGDSEIDQLFK 714
>21079
          Length = 878

 Score = 79.0 bits (193), Expect = 6e-15,   Method: Compositional matrix adjust.
 Identities = 46/143 (32%), Positives = 76/143 (53%), Gaps = 3/143 (2%)
 Frame = +1

Query: 398 PFLTQLHSCFQTVDRLYFVMEYVNGGDLMYH-IQQVGKFKEPQAVFYAAEISIGLFFLHK 456
           P L  L   F+    +  VME+V  G+L    I+      E   V +  +I  G+ ++H 
Sbjct: 4   PKLLMLWDAFEAPRTMVLVMEFVGAGELFERVIRDDFVLTERDCVHFVRQICSGVGYMHT 183

Query: 457 RGIIYRDLKLDNVML--DSEGHIKIADFGMCKEHMMDGVTTRTFCGTPDYIAPEIIAYQP 514
           + I++ DLK +NV+   D+   IKI DFG+ + +   G + +   GTP++IAPE++ Y  
Sbjct: 184 QSILHLDLKPENVLCVSDNSNQIKIIDFGLARFYK-PGDSLQVLFGTPEFIAPEVVNYDE 360

Query: 515 YGKSVDWWAYGVLLYEMLAGQPP 537
              + D W+ GV+ Y +L+G  P
Sbjct: 361 INFTTDMWSIGVICYILLSGLSP 429
>13212
          Length = 1067

 Score = 78.2 bits (191), Expect = 1e-14,   Method: Compositional matrix adjust.
 Identities = 51/170 (30%), Positives = 84/170 (49%), Gaps = 7/170 (4%)
 Frame = -1

Query: 437 EPQAVFYAAEISIGLFFLHKRGIIYRDLKLDNVMLDSEGHIKIADFGMCKEHMMDGVTTR 496
           E Q  +   E+ + L FLH+  +I+RD+K  NV+L  +G +K+ADFG+  ++        
Sbjct: 983 EAQICYVCHEMCMALDFLHRHHVIHRDIKAGNVLLTIDGEVKLADFGVSAKNTQTQQKRD 804

Query: 497 TFCGTPDYIAPEIIAYQ-----PYGKSVDWWAYGVLLYEMLAGQPPFDGEDEDELFQSIM 551
           TF GTP ++APE++  +     PY    D W+ GV L E    +PP     E    + ++
Sbjct: 803 TFIGTPYWMAPEVVLCETLKDTPYDFKADIWSLGVTLIEFAQIEPP---NKEMHPMRVLI 633

Query: 552 EHNVSYPKSLS--KEAVSICKGLMTKHPAKRLGCGPEGERDVREHAFFRR 599
           + + S P +L   K+   + K  + K   K     P    ++ EH F +R
Sbjct: 632 KIHKSDPPTLEKPKKWTKLFKDFIAKCLVKDPNLRPTA-AELLEHPFMKR 486
>29581
          Length = 1278

 Score = 76.3 bits (186), Expect = 4e-14,   Method: Compositional matrix adjust.
 Identities = 56/222 (25%), Positives = 96/222 (43%), Gaps = 31/222 (13%)
 Frame = -2

Query: 408  QTVDRLYFVMEYVNGGDLMYHIQQVGKFKEPQAVFYAAEISIGLFFLHKRGIIYRDLKLD 467
            +++D L+ VMEY               F E Q      ++  GL +LH+  II+RDLK+ 
Sbjct: 1139 KSLDSLFLVMEYCEQDLASLLDNMPAPFSESQVKCIVLQLLKGLRYLHEAFIIHRDLKVS 960

Query: 468  NVMLDSEGHIKIADFGMCKEHMMDGVTTRTFCGTPDYIAPEII-AYQPYGKSVDWWAYGV 526
            N+++  +G +KIADFG+ + +            T  Y APE++   + +  ++D W+ G 
Sbjct: 959  NLLMTDKGCVKIADFGLARNYGKPQKPMTPKVVTLWYRAPELLFGSKTHSTAIDMWSAGC 780

Query: 527  LLYEMLAGQPPFDGEDEDELFQSIME-----HNVSYP----------------------- 558
            +L E+L  +P   G  + +  + IME     ++  +P                       
Sbjct: 779  ILGELLGHKPLMPGRSDLQQIELIMELLGTPNDTIWPGFSQLPAFEQFTLKKQPYNNLRH 600

Query: 559  --KSLSKEAVSICKGLMTKHPAKRLGCGPEGERDVREHAFFR 598
                LS+  + +  GL   HP KR         D  EH++F+
Sbjct: 599  TFPWLSESGIRLLNGLFMYHPQKR-----ATAEDCLEHSYFK 489
>14126
          Length = 1265

 Score = 72.0 bits (175), Expect = 7e-13,   Method: Compositional matrix adjust.
 Identities = 58/221 (26%), Positives = 101/221 (45%), Gaps = 12/221 (5%)
 Frame = +3

Query: 344 VLGKGSFGKVMLA-DRKGTEELYAIKILKKDVVIQDDDVECTMVEKRVLALL------DK 396
           V+G G++G V  A D +   E  A+K ++    + + +    M+  R +++L      + 
Sbjct: 210 VIGNGAYGTVYKARDLRNQGEFVAMKRIR----LNNTEEGMPMMAIREISMLKQLEQYEH 377

Query: 397 PPFLTQLHSCFQTVD----RLYFVMEYVNGGDLMYHIQQVGKFKEPQAVF-YAAEISIGL 451
           P  +  L     T+     RL  V EY+      Y  +       P  +     ++  G+
Sbjct: 378 PNVVRLLDVSHNTITDREIRLNLVFEYIEHDLATYLAKCPSPGLGPDRIKDLMLQLLNGV 557

Query: 452 FFLHKRGIIYRDLKLDNVMLDSEGHIKIADFGMCKEHMMDGVTTRTFCGTPDYIAPEIIA 511
            FLH   I++RDLK  N+++  +G +K+ADFG+ + +      T T   T  Y +PE++ 
Sbjct: 558 DFLHSNRIVHRDLKPQNLLISKDGRLKLADFGLARIYSFHMALT-TVVVTLWYRSPEVLM 734

Query: 512 YQPYGKSVDWWAYGVLLYEMLAGQPPFDGEDEDELFQSIME 552
              YG SVD W+ G +  E+   +  F G  E +  + I E
Sbjct: 735 QAEYGTSVDIWSCGCIFAELFTRRALFKGSSEFDQLKKIFE 857
>01756
          Length = 1858

 Score = 70.1 bits (170), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 61/251 (24%), Positives = 116/251 (46%), Gaps = 17/251 (6%)
 Frame = -3

Query: 319  SPSEDRKQPSNNLDRVKLTDFNFLMVLGKGSFGKVMLADRKGTEELYAIKILKKDVVIQD 378
            SP E  K P  + D      +  L  +G+G+FG+V  A  K T+++ A+K      V+ D
Sbjct: 1784 SPYETLKFPFCDED----AKYEKLAKIGQGTFGEVFKARCKKTKQVVAMK-----KVLMD 1632

Query: 379  DDVE----CTMVEKRVLALLDKPPFLTQLHSC---FQTVDR----LYFVMEYV--NGGDL 425
            ++ E      + E ++L LL+    +  +  C     + +R     Y V E+   +   L
Sbjct: 1631 NEKEGFPITALREIKILQLLNHENVVDLIEICSTKATSANRYKSMFYLVFEFCEHDLAGL 1452

Query: 426  MYHIQQVGKFKEPQAVFYAAEISIGLFFLHKRGIIYRDLKLDNVMLDSEGHIKIADFGMC 485
            + ++  V  F  P+      ++  GL+++H+  I++RD+K  N+++  +G +K+ADFG+ 
Sbjct: 1451 LSNMSVV--FNLPEIKEVMKQLMNGLYYIHRNKILHRDMKAANILITKQGVLKLADFGLA 1278

Query: 486  KEHMMDGVTTRTFCG---TPDYIAPE-IIAYQPYGKSVDWWAYGVLLYEMLAGQPPFDGE 541
            +   ++      +     T  Y  PE ++  + Y  ++D W  G ++ EM    P   G 
Sbjct: 1277 RAFSVNLRQPNRYTNRVVTLWYRPPELLLGDRNYSTAIDQWGAGCIMAEMWTRNPIMQGT 1098

Query: 542  DEDELFQSIME 552
             E      I +
Sbjct: 1097 TEQNQLTLITQ 1065
>27546
          Length = 426

 Score = 69.7 bits (169), Expect = 3e-12,   Method: Compositional matrix adjust.
 Identities = 34/100 (34%), Positives = 56/100 (56%)
 Frame = -1

Query: 387 EKRVLALLDKPPFLTQLHSCFQTVDRLYFVMEYVNGGDLMYHIQQVGKFKEPQAVFYAAE 446
           E  +L  LD P  + Q+HS  Q   +++  M Y   GD++ HI++ G   E Q   +  +
Sbjct: 330 ELEILTRLDHPN-IIQIHSILQRGPKIFIFMRYAEKGDMLSHIKKTGPIDEAQTKVWFFQ 154

Query: 447 ISIGLFFLHKRGIIYRDLKLDNVMLDSEGHIKIADFGMCK 486
           ++  L +LH   I +RDLK +N++L    ++KIADFG  +
Sbjct: 153 MAKALQYLHSHDIAHRDLKCENILLSKRLNVKIADFGFAR 34
>16549
          Length = 607

 Score = 69.7 bits (169), Expect = 4e-12,   Method: Composition-based stats.
 Identities = 34/109 (31%), Positives = 64/109 (58%), Gaps = 2/109 (1%)
 Frame = +2

Query: 171 EKLHVTVRDAKNLIPMDPNGLSDPYVKLKLIPDPKNESKQKTKTIRSTLNPQWNESFTFK 230
           + LH+ V   ++L       L  PYVK  L+PDP+ ++K+KTK ++ +++P +NE   ++
Sbjct: 2   DSLHIMVMHVRDL--ARSAELPSPYVKTYLLPDPEKQTKRKTKIVKHSVHPTFNEVLQYR 175

Query: 231 LKPSD-KDRRLSVEIWDWDRTTRNDFMGSLSFGVSEL-MKMPASGWYKL 277
           +K ++ + R L V +WD D    N+F+G++   + +L +    + WY L
Sbjct: 176 MKETETRHRTLQVTVWDHDMLKENNFLGAVYLRLRDLELSDDTAKWYTL 322
>28638
          Length = 1458

 Score = 52.8 bits (125), Expect(2) = 4e-12,   Method: Compositional matrix adjust.
 Identities = 32/100 (32%), Positives = 51/100 (51%), Gaps = 4/100 (4%)
 Frame = -1

Query: 443 YAAEISIGLFFLH--KRGIIYRDLKLDNVMLDS--EGHIKIADFGMCKEHMMDGVTTRTF 498
           +A ++   L FL   +  II+ DLK +N++L +     IKI DFG        G     +
Sbjct: 822 FAQQLCTALLFLATPEMNIIHCDLKPENILLCNPKRSAIKIVDFG---SSCQLGQRIYQY 652

Query: 499 CGTPDYIAPEIIAYQPYGKSVDWWAYGVLLYEMLAGQPPF 538
             +  Y +PE++   PY  ++D W+ G +L EM  G+PP 
Sbjct: 651 IQSRFYRSPEVLLGVPYDLAIDMWSLGCILVEMHTGEPPL 532

 Score = 36.6 bits (83), Expect(2) = 4e-12,   Method: Compositional matrix adjust.
 Identities = 36/131 (27%), Positives = 58/131 (44%), Gaps = 4/131 (3%)
 Frame = -3

Query: 292  EGDEEGNMELR---QKFEKAKLGPAGNKVISPSEDRKQPSNNLDRVKLTDFNFLMVLGKG 348
            +GDE GN + +     F         + +I+P E        LDR ++       ++GKG
Sbjct: 1258 QGDESGNKKNKVNIHVFNDGYDDSNHDYIINPGEKW------LDRYEIDS-----LIGKG 1112

Query: 349  SFGKVMLADRKGTEELYAIKILK-KDVVIQDDDVECTMVEKRVLALLDKPPFLTQLHSCF 407
            SFG+V+ A   G +E  AIKI+K K   +    +E  ++E       D   ++ +L   F
Sbjct: 1111 SFGQVVKAYDHGDQEQVAIKIIKNKKPFLNQAQIEVKLLELMNRHDADNXYYIVRLKRHF 932

Query: 408  QTVDRLYFVME 418
               + L  V E
Sbjct: 931  MFRNHLCLVFE 899
>21433
          Length = 590

 Score = 68.9 bits (167), Expect = 6e-12,   Method: Composition-based stats.
 Identities = 40/96 (41%), Positives = 59/96 (61%)
 Frame = +2

Query: 443 YAAEISIGLFFLHKRGIIYRDLKLDNVMLDSEGHIKIADFGMCKEHMMDGVTTRTFCGTP 502
           Y  ++S  L + H R +I+RD+K +N++L  +G +KIADFG    H      T T CGT 
Sbjct: 182 YIYQLSSALEYCHYRKVIHRDIKPENLLLGLKGDLKIADFGW-SVHAPSSRRT-TMCGTL 355

Query: 503 DYIAPEIIAYQPYGKSVDWWAYGVLLYEMLAGQPPF 538
           DY+ PE++  + + ++VD W+ GVL YE L G PP 
Sbjct: 356 DYLPPEMVEGKTHDENVDLWSLGVLCYEFLVGTPPL 463
>19094
          Length = 898

 Score = 68.9 bits (167), Expect = 7e-12,   Method: Compositional matrix adjust.
 Identities = 36/87 (41%), Positives = 53/87 (60%), Gaps = 1/87 (1%)
 Frame = +1

Query: 450 GLFFLHKRGIIYRDLKLDNVMLDSEGHIKIADFGMCKEHMMDGVTTR-TFCGTPDYIAPE 508
           GL +LH R  I+RD+K  N++L++EGH K+ADFG+  + + D +  R T  GTP ++APE
Sbjct: 94  GL*YLHSRRKIHRDIKAGNILLNNEGHAKLADFGVAGQ-LTDTMAKRNTVIGTPYWMAPE 270

Query: 509 IIAYQPYGKSVDWWAYGVLLYEMLAGQ 535
           +I    Y    D W+ G+   EM  G 
Sbjct: 271 VIQEIGYDCVADIWSLGITALEMAEGN 351
>32957
          Length = 645

 Score = 68.2 bits (165), Expect = 1e-11,   Method: Composition-based stats.
 Identities = 29/54 (53%), Positives = 37/54 (68%)
 Frame = +3

Query: 482 FGMCKEHMMDGVTTRTFCGTPDYIAPEIIAYQPYGKSVDWWAYGVLLYEMLAGQ 535
           F +C E    G  TRTFCGT +Y+APE+   + YGK VDWW  G+LL+E+LA Q
Sbjct: 3   FALCVEK--SGGRTRTFCGTREYMAPEVHERKEYGKEVDWWGLGILLHELLAAQ 158
>00392
          Length = 668

 Score = 67.8 bits (164), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 43/162 (26%), Positives = 90/162 (55%), Gaps = 7/162 (4%)
 Frame = +3

Query: 413 LYFVMEYVNGGDLMYHIQQVGKFKEPQAVF---YAAEISIGLFFLHKRG--IIYRDLKLD 467
           +  V E +  G L  +++   +FK+P       +  ++  GL+FLH R   +I+RDLK D
Sbjct: 171 IILVTELMTSGTLKTYLK---RFKKPNVKILKNWCRQVLKGLYFLHTRTPPVIHRDLKCD 341

Query: 468 NVMLDS-EGHIKIADFGMCKEHMMDGVTTRTFCGTPDYIAPEIIAYQPYGKSVDWWAYGV 526
           N+ +    G +KI D G+    + +    ++  GTP+++APE+   + Y ++VD +A+G+
Sbjct: 342 NIFITGPTGSVKIGDLGLAT--LKNQSFAKSVIGTPEFMAPEMYE-EHYDEAVDVYAFGM 512

Query: 527 LLYEMLAGQPPF-DGEDEDELFQSIMEHNVSYPKSLSKEAVS 567
            + EM + + P+ +  +  ++++ +    +  P++L K A++
Sbjct: 513 CMLEMASSEYPYSECSNAAQIYKRVTSGVL--PEALDKVAIT 632
>14116
          Length = 1017

 Score = 67.4 bits (163), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 57/217 (26%), Positives = 105/217 (48%), Gaps = 19/217 (8%)
 Frame = -1

Query: 336 LTDFNFLMV---LGKGSFGKV-----MLADRKGTEELYAIKILKKDVVIQDDDVECTMVE 387
           L D  FL +   +GKG+FG V      L ++KG + L A+K L  +   ++ +++  + E
Sbjct: 648 LIDREFLTMGEEIGKGNFGCVKRGFLTLPEQKG-DILVAVKTLHNNNP-REIELQSFLQE 475

Query: 388 KRVLALLDKPPFLTQLHSCFQTVDRLYFVMEYVNGGDLMYHI---QQVGKFKEPQAVFYA 444
             ++        LT +  C    D    V+ ++  GDL+ +I   Q     K+   + Y 
Sbjct: 474 ALIMKDFHHSNVLTLIGICLNLDDMPLVVLPFMKHGDLLTYIRDDQHQPTIKD--LIMYG 301

Query: 445 AEISIGLFFLHKRGIIYRDLKLDNVMLDSEGHIKIADFGMCKEHMMDGVTTRTFCGTPD- 503
            +I+ G+ +L     ++RDL   N MLD + H+K+ADFG+ ++     +  + +  + + 
Sbjct: 300 VDIARGMDYLAGLKFVHRDLAARNCMLDEDFHVKVADFGLARD-----IYEKEYYSSENK 136

Query: 504 -------YIAPEIIAYQPYGKSVDWWAYGVLLYEMLA 533
                  ++A E +    Y    D W+YGV+L+E+L 
Sbjct: 135 KAKLPVKWMALESLEKGNYDSKTDVWSYGVVLWELLT 25
>04852
          Length = 1462

 Score = 66.2 bits (160), Expect = 4e-11,   Method: Compositional matrix adjust.
 Identities = 60/223 (26%), Positives = 101/223 (45%), Gaps = 29/223 (13%)
 Frame = +1

Query: 366 AIKILKKDV--VIQDDDVECTMVEKRVLALLDKPPFLTQLHSCFQTVDRLYFVMEYVNGG 423
           A+K+L+  V  V + D V+   V K V  +      +  L  C Q    L+ ++E+   G
Sbjct: 31  AVKMLRDIVTAVEEQDFVQELQVMKAVKKMGSHINIVNFLGCCTQG-GPLWVIVEFAKNG 207

Query: 424 DLMYHIQQV-------GKFKEPQ------------------AVFYAAEISIGLFFLHKRG 458
           +L   ++         GKF  PQ                   + YA +I+ G+ FL  R 
Sbjct: 208 NLRDFLESCRDGINGYGKFVSPQDPGWYTKTPGGHVIRRKNLLSYAFQIARGMEFLASRK 387

Query: 459 IIYRDLKLDNVMLDSEGHIKIADFGMCKEHMMDGVTTRTFCGTP-DYIAPEIIAYQPYGK 517
            I+RDL   NV++  E  +KIADFG+ +    D    R+    P  ++APE +    Y  
Sbjct: 388 CIHRDLAARNVLVTEEHVLKIADFGLSRTG--DYYKKRSGGRLPVKWMAPEALFDMRYTT 561

Query: 518 SVDWWAYGVLLYEMLA-GQPPFDGEDEDELFQSIMEHNVSYPK 559
             D W++GV+L+E+ + G  P+     +EL+  +++     P+
Sbjct: 562 KSDVWSFGVVLWEIFSLGGMPYASIPNEELYSKLLDDAYRMPR 690
>37602
          Length = 804

 Score = 65.5 bits (158), Expect = 7e-11,   Method: Compositional matrix adjust.
 Identities = 33/90 (36%), Positives = 50/90 (55%), Gaps = 2/90 (2%)
 Frame = -1

Query: 411 DRLYFVMEYVNGGDL--MYHIQQVGKFKEPQAVFYAAEISIGLFFLHKRGIIYRDLKLDN 468
           ++L+  MEY  GG +  +YH+   G   EPQ  F   E   GL +LH+RG ++RD+K  N
Sbjct: 300 EKLWIAMEYCGGGSMQDIYHV--TGPLTEPQIAFVCRETLKGLHYLHRRGKMHRDIKGAN 127

Query: 469 VMLDSEGHIKIADFGMCKEHMMDGVTTRTF 498
           ++L  EG +K+ADF     +    V  + F
Sbjct: 126 ILLTEEGDVKLADFWRVSSNHSHNVQKKVF 37
>29179
          Length = 1113

 Score = 65.1 bits (157), Expect = 9e-11,   Method: Compositional matrix adjust.
 Identities = 49/134 (36%), Positives = 74/134 (55%), Gaps = 6/134 (4%)
 Frame = -3

Query: 148 PSLCGMDHTEKRGRIYLKAEVTDEKLHVTVR--DAKNLIPMDPNGLSDPYVKLKLIPDPK 205
           P + G+D+  K GRI        + L +T+R   A +L   D  G SDPYVK+ L+PD K
Sbjct: 568 PIVEGVDY--KLGRIQFGLMYDFQNLTLTLRIIRAVDLPAKDVTGTSDPYVKILLLPDKK 395

Query: 206 NESKQKTKTIRSTLNPQWNESFTFKLKPSDK--DRRLSVEIWDWDRTTRNDFMGSLSFGV 263
           +  K  TK  +  LNP WNE F F+  P +K  ++ L +++ D+DR +R+D +G     +
Sbjct: 394 H--KLLTKVKKRNLNPHWNECFLFEGWPHNKLLEKTLYLQVIDYDRFSRDDPIGETYLPL 221

Query: 264 SE--LMKMPASGWY 275
           +E  L + P S  Y
Sbjct: 220 NEIDLSQSPVSWKY 179
>04591
          Length = 1117

 Score = 63.2 bits (152), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 32/109 (29%), Positives = 58/109 (53%), Gaps = 1/109 (0%)
 Frame = -2

Query: 445 AEISIGLFFLHKRGIIYRDLKLDNVMLDSEGHIKIADFGMCKEHMMDGVTTRTFCGTPDY 504
           +++  GLF++H + I++RD+K  N++L  +G +K+ADFG+ +  +     T     T  Y
Sbjct: 876 SQLLNGLFYIHTKQILHRDIKAANILLTRDGVLKLADFGLSRPWVKSKRLTNRVV-TLWY 700

Query: 505 IAPE-IIAYQPYGKSVDWWAYGVLLYEMLAGQPPFDGEDEDELFQSIME 552
             PE ++  + YG  +D W  G ++ EM + +P   G  E      I +
Sbjct: 699 RPPELLLGEREYGPEIDMWGVGCIMAEMWSRKPLMQGRSEQHQLSLITD 553
>17591
          Length = 474

 Score = 51.6 bits (122), Expect(2) = 3e-10,   Method: Compositional matrix adjust.
 Identities = 35/94 (37%), Positives = 55/94 (58%), Gaps = 11/94 (11%)
 Frame = +3

Query: 579 KRLGCGPEGERDVREHAFFRRIDWEKLENREIQPPFKPKVCGK-GAENFDKFFTRGQPV- 636
           +RLG   + E +++E AFF  I+W+ L N+++QPP+ P V G+    +FD  F R +PV 
Sbjct: 153 ERLGAKRDFE-EIQEKAFFADINWDDLYNKKVQPPYNPNVSGQLDLRHFDPEFVR-EPVP 326

Query: 637 -------LTPPDQLVIANIDQSD--FEGFSYVNP 661
                       +LV A++ ++D  F+GFSYV P
Sbjct: 327 ASVGRSGGGSSSKLVSASVMEADAVFDGFSYVPP 428

 Score = 31.6 bits (70), Expect(2) = 3e-10,   Method: Composition-based stats.
 Identities = 15/54 (27%), Positives = 27/54 (50%)
 Frame = +2

Query: 529 YEMLAGQPPFDGEDEDELFQSIMEHNVSYPKSLSKEAVSICKGLMTKHPAKRLG 582
           +EML G PPF   D  E++++I+   +    ++S    +I + L+ K      G
Sbjct: 2   FEMLYGLPPFYSRDTSEMYENILYKPLRLRTNVSAAGRNILEELLKKEKGGETG 163
>09007
          Length = 1440

 Score = 63.2 bits (152), Expect = 4e-10,   Method: Compositional matrix adjust.
 Identities = 61/238 (25%), Positives = 104/238 (43%), Gaps = 13/238 (5%)
 Frame = -1

Query: 345 LGKGSFGKVMLA---DRKGTEELYAIKILKKDVVIQDDDVECTMVEKRVLALLDKPPFLT 401
           LG+G FG V  A      G +   A+K L KD + +D   +  + E  ++ +LD    + 
Sbjct: 855 LGQGHFGTVRQAIWTAESGEKVQVAVKCLSKDKIHKDG--QEFLKETAIMQMLDHENIVR 682

Query: 402 QLHSCFQTVDRLYFVMEYVNGGDLMYHIQQVGK---FKEPQAVFYAAEISIGLFFLHKRG 458
                      +  V E      L+  +++V     F  P+   ++ ++  G+ +L  + 
Sbjct: 681 VYGVVMDNGADIMLVTELAPMRSLLECVKEVSARVDFSVPRLCDFSQQVCDGMSYLESKR 502

Query: 459 IIYRDLKLDNVMLDSEGHIKIADFGMC------KEHMMDGVTTRTFCGTPDYIAPEIIAY 512
           +++RDL   N++L S+  +KI+D G+       KE+     T         + APE    
Sbjct: 501 LVHRDLAARNILLFSKSKVKISDVGVSGALGAGKEYYQSQQTIH-LQNAVAWCAPESFRN 325

Query: 513 QPYGKSVDWWAYGVLLYEMLA-GQPPFDGEDEDELFQSIMEHNVSYPKSLSKEAVSIC 569
             +  + D WA+GVLL+E    G  P+ G +     Q IME  V  P+S   E   +C
Sbjct: 324 LCFSSASDVWAFGVLLWEFFTHGFQPWAGLNG----QQIME-AVDAPQSQRLEQPDLC 166
>11185
          Length = 473

 Score = 62.4 bits (150), Expect = 6e-10,   Method: Composition-based stats.
 Identities = 36/117 (30%), Positives = 52/117 (44%), Gaps = 25/117 (21%)
 Frame = +1

Query: 443 YAAEISIGLFFLHKRGIIYRDLKLDNVMLDSEGHIKIADFGMCK---------------- 486
           +   +  GL ++H  GI++ DL+   V+LD+ G +K ADFG+ K                
Sbjct: 16  FGIHLVTGLHYIHSLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEA 195

Query: 487 ---------EHMMDGVTTRTFCGTPDYIAPEIIAYQPYGKSVDWWAYGVLLYEMLAG 534
                    E MM  V T    G+P Y+APE+          D WA G + YEM +G
Sbjct: 196 GDQWNIQSAEEMMKQVPTS---GSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFSG 357
>38560
          Length = 479

 Score = 62.0 bits (149), Expect = 8e-10,   Method: Compositional matrix adjust.
 Identities = 32/86 (37%), Positives = 47/86 (54%), Gaps = 1/86 (1%)
 Frame = -3

Query: 497 TFCGTPDYIAPEIIAYQPY-GKSVDWWAYGVLLYEMLAGQPPFDGEDEDELFQSIMEHNV 555
           T CG+P Y APE+I+   Y G   D W+ GVLLY +L G  PFD E    L Q   +   
Sbjct: 408 TCCGSPAYAAPELISGLEYLGSEADIWSMGVLLYALLCGYLPFDDEKXSHL*QKNQKRKD 229

Query: 556 SYPKSLSKEAVSICKGLMTKHPAKRL 581
             P+ LS++   + +G++   P+ R+
Sbjct: 228 EVPEWLSEDTTKLLEGMLQTDPSHRI 151
>07940
          Length = 1336

 Score = 59.7 bits (143), Expect = 4e-09,   Method: Compositional matrix adjust.
 Identities = 39/124 (31%), Positives = 65/124 (52%), Gaps = 4/124 (3%)
 Frame = -3

Query: 428 HIQQVGKFKEPQ-AVFYAAEISIGLFFLHKRGIIYRDLKLDNVMLDSEGHIKIADFGMCK 486
           H Q + K   P+  + YA +++ G+ +L  +  I+RDL   NV++  E  +KIADFG+ +
Sbjct: 380 HRQDMLKMLTPKDLISYAYQVARGMEYLASKQCIHRDLAARNVLVAEEYVLKIADFGLTR 201

Query: 487 EHMMDGVTTRTFCGT--PDYIAPEIIAYQPYGKSVDWWAYGVLLYEMLA-GQPPFDGEDE 543
                    +T  G     ++APE +  + Y    D W+YGVLL+E+   G  P+     
Sbjct: 200 NLQQFDYYRKTTDGRLPVKWMAPEALFDRKYTSKSDVWSYGVLLWEIFTLGGNPYPSVPV 21

Query: 544 DELF 547
           ++LF
Sbjct: 20  EDLF 9

 Score = 32.3 bits (72), Expect = 0.66,   Method: Compositional matrix adjust.
 Identities = 23/86 (26%), Positives = 41/86 (47%), Gaps = 5/86 (5%)
 Frame = -3

Query: 345 LGKGSFGKVMLADRKG-----TEELYAIKILKKDVVIQDDDVECTMVEKRVLALLDKPPF 399
           LG+G+FG VM  +  G          A+K+LK+D    D ++   + E  ++ ++ K   
Sbjct: 818 LGEGAFGLVMKGEAMGIFKDNNSVTVAVKMLKEDAT--DREMMDLIREMEMMKVIGKHKN 645

Query: 400 LTQLHSCFQTVDRLYFVMEYVNGGDL 425
           +  L  C      LY ++E+   G+L
Sbjct: 644 IINLLGCCTQRGALYVIVEFAPHGNL 567
>26711
          Length = 405

 Score = 58.9 bits (141), Expect = 7e-09,   Method: Composition-based stats.
 Identities = 30/94 (31%), Positives = 52/94 (55%), Gaps = 2/94 (2%)
 Frame = -2

Query: 454 LHKRGIIYRDLKLDNVML--DSEGHIKIADFGMCKEHMMDGVTTRTFCGTPDYIAPEIIA 511
           +H +G+++ DLK  N++L  D    +++ DFG+ ++ +     T    GTP + +PE + 
Sbjct: 368 VHAQGVVHMDLKPSNLLLSGDKLDSVQLIDFGLARK-LYPPQETFLNHGTPGFTSPEALD 192

Query: 512 YQPYGKSVDWWAYGVLLYEMLAGQPPFDGEDEDE 545
            +P   + D W  GVL Y +L+GQ PF  +   E
Sbjct: 191 VKPISTASDVWGVGVLAYILLSGQSPFQADSATE 90
>12672
          Length = 773

 Score = 57.8 bits (138), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 36/116 (31%), Positives = 61/116 (52%), Gaps = 4/116 (3%)
 Frame = +3

Query: 450 GLFFLHKRGIIYRDLKLDNVMLDSEGHIKIADFG-MCKEHMMDGVTTR---TFCGTPDYI 505
           G+ +L+  G ++RD+K  N++LDSE   K+ DF  +      +G T +      GT  Y+
Sbjct: 27  GIQYLNDNGHVHRDIKTANILLDSEYTAKVGDFATVVSAPSGEGKTVQNASVVIGTAAYL 206

Query: 506 APEIIAYQPYGKSVDWWAYGVLLYEMLAGQPPFDGEDEDELFQSIMEHNVSYPKSL 561
           APE I +    K +D +++GV+L E++ G    D   E+    S +  NV  P+ +
Sbjct: 207 APEAIHFDVSTK-LDSYSFGVVLLEVITGLVAQDYSREERTLSSHIMENVEEPEEI 371
>30339
          Length = 384

 Score = 57.8 bits (138), Expect = 2e-08,   Method: Composition-based stats.
 Identities = 29/42 (69%), Positives = 32/42 (76%)
 Frame = -2

Query: 319 SPSEDRKQPSNNLDRVKLTDFNFLMVLGKGSFGKVMLADRKG 360
           SPS DR + S   DR  L DFNF+ VLGKGSFGKVMLA+RKG
Sbjct: 119 SPSSDRGRSS---DRFHLHDFNFIKVLGKGSFGKVMLAERKG 3
>31935
          Length = 554

 Score = 56.6 bits (135), Expect = 3e-08,   Method: Composition-based stats.
 Identities = 28/82 (34%), Positives = 45/82 (54%)
 Frame = -3

Query: 154 DHTEKRGRIYLKAEVTDEKLHVTVRDAKNLIPMDPNGLSDPYVKLKLIPDPKNESKQKTK 213
           +H   R ++ +      +KL VT+    N+   DP+ + DPYVKL L+P    ESK+KT 
Sbjct: 549 EHGLGRIQLTITYSAQRQKLDVTIHKIMNIPLRDPSSIPDPYVKLHLLPGRSKESKRKTS 370

Query: 214 TIRSTLNPQWNESFTFKLKPSD 235
            I+   NP ++ SF + +  S+
Sbjct: 369 IIKDNCNPVYDASFEYLISISE 304
>35187
          Length = 593

 Score = 56.6 bits (135), Expect = 4e-08,   Method: Compositional matrix adjust.
 Identities = 24/50 (48%), Positives = 31/50 (62%)
 Frame = -3

Query: 37  HKFIARFFKQPTFCSHCTDFIWGFGKQGFQCQVCCFVVHKRCHEFVTFSC 86
           H F  + F +PT+C HCTD +WG    G+ C+VC FVVH RC + V   C
Sbjct: 315 HFFTKKTFHKPTYCHHCTDILWGLIGVGYVCEVCNFVVHDRCMKTVVSPC 166

 Score = 45.8 bits (107), Expect = 6e-05,   Method: Compositional matrix adjust.
 Identities = 23/59 (38%), Positives = 31/59 (52%)
 Frame = -3

Query: 93  PDTDDPRSKHKFKIHTYGSPTFCDHCGSLLYGLIHQGMKCDTCDMNVHKQCVINVPSLC 151
           P   D    H F   T+  PT+C HC  +L+GLI  G  C+ C+  VH +C+  V S C
Sbjct: 342 PVPPDHGHGHFFTKKTFHKPTYCHHCTDILWGLIGVGYVCEVCNFVVHDRCMKTVVSPC 166
>17300
          Length = 480

 Score = 55.8 bits (133), Expect = 5e-08,   Method: Composition-based stats.
 Identities = 31/97 (31%), Positives = 56/97 (57%), Gaps = 5/97 (5%)
 Frame = +1

Query: 447 ISIGLFFLHKRGIIYRDLKLDNVMLDSEGHIKIADFGMCKE---HMMDGVTTRTFCGTP- 502
           IS G+  L   G ++RDL   N++++     K+ADFG+ +E      +G  T      P 
Sbjct: 1   ISSGMGXLADMGYVHRDLAARNILVNEILVCKVADFGLSREIESDTTEGAYTTKGGKIPV 180

Query: 503 DYIAPEIIAYQPYGKSVDWWAYGVLLYEMLA-GQPPF 538
            + APE IAY+ +  + D W++GV+++E+++ G+ P+
Sbjct: 181 RWTAPEAIAYRKFTSASDVWSFGVVMWEVMSYGERPY 291
>01966
          Length = 1735

 Score = 55.8 bits (133), Expect = 6e-08,   Method: Compositional matrix adjust.
 Identities = 36/106 (33%), Positives = 55/106 (51%), Gaps = 6/106 (5%)
 Frame = -1

Query: 411  DRLYFVMEYVNGGDLMYHIQQVGKFKEPQAV------FYAAEISIGLFFLHKRGIIYRDL 464
            +RL+ V E+++    MY    + KF E   +       Y  +I  G+ F H+R I++RDL
Sbjct: 1495 ERLFLVFEFLSMDLKMY----IDKFPEGVVLDRRLVKSYVFQIVTGINFCHQRRIVHRDL 1328

Query: 465  KLDNVMLDSEGHIKIADFGMCKEHMMDGVTTRTFCGTPDYIAPEII 510
            K  N++++  G IKIADFGM +   +          T  Y APEI+
Sbjct: 1327 KPQNLLINHTGAIKIADFGMARTFALPVRAYTHEVVTLWYRAPEIL 1190
>03508
          Length = 1463

 Score = 55.1 bits (131), Expect = 9e-08,   Method: Compositional matrix adjust.
 Identities = 37/126 (29%), Positives = 60/126 (47%), Gaps = 2/126 (1%)
 Frame = +1

Query: 415 FVMEYVNGGDLMYHIQQVGKFKEPQAVFYAAEISIGLFFLHKRGIIYRDLKLDNVMLDSE 474
            + E+VN  D     Q    F +    FY  E+   L F H  GI++RD+K  NVM+D E
Sbjct: 811 LIFEHVNNTDFK---QLYQTFTDYDIRFYLYELMKALDFCHSMGIMHRDVKPHNVMIDHE 981

Query: 475 G-HIKIADFGMCKEHMMDGVTTRTFCGTPDYIAPEIIA-YQPYGKSVDWWAYGVLLYEML 532
              +++ D+G+  E    G+       +  +  PE++  YQ Y  S+D W+ G +   M+
Sbjct: 982 NKKLRLIDWGLA-EFYHPGMEYNVRVASRYFKGPELLLDYQMYDYSLDMWSLGCMFASMI 1158

Query: 533 AGQPPF 538
             + P 
Sbjct: 1159FRKEPL 1176
>19761
          Length = 473

 Score = 55.1 bits (131), Expect = 9e-08,   Method: Compositional matrix adjust.
 Identities = 37/154 (24%), Positives = 69/154 (44%), Gaps = 6/154 (3%)
 Frame = -3

Query: 428 HIQQVGKFKEPQAVFYAAEISIGLFFLHKRG--IIYRDLKLDNVMLDSEGHIKIADFGMC 485
           H+       E   V +  + +  L ++H     I++RDLK  N+ +  +G +++ D G+ 
Sbjct: 453 HLGFTAGLPERLIVCWLMQTASALNYMHTHTPVILHRDLKPQNIYVTEKGDVRLGDLGLA 274

Query: 486 KEHMMDGVTTRTFCGTPDYIAPEIIAYQPYGKSVDWWAYGVLLYEMLAGQPPFDGEDEDE 545
           ++         +  GT  Y++PEI++ QPY    D W+ G + Y++   +    G DE  
Sbjct: 273 RKLTGPADFATSQVGTIMYLSPEILSQQPYNSKSDIWSLGCVFYDITGKK----GSDEMG 106

Query: 546 ----LFQSIMEHNVSYPKSLSKEAVSICKGLMTK 575
               L Q +    +  P   S+E       ++TK
Sbjct: 105 VMFLLVQVMGGRKLPLPDHYSQEFRDTISRMLTK 4
>33586
          Length = 551

 Score = 47.4 bits (111), Expect(2) = 1e-07,   Method: Composition-based stats.
 Identities = 21/53 (39%), Positives = 31/53 (58%), Gaps = 1/53 (1%)
 Frame = +2

Query: 396 KPP-FLTQLHSCFQTVDRLYFVMEYVNGGDLMYHIQQVGKFKEPQAVFYAAEI 447
           +PP F+  LH  FQT  +LY ++E++ GGDL   + +   F E    FY AE+
Sbjct: 392 QPPLFIVHLHYAFQTEGKLYLILEFLRGGDLFTRLSKEVMFTEEDVKFYLAEL 550

 Score = 26.9 bits (58), Expect(2) = 1e-07,   Method: Composition-based stats.
 Identities = 11/22 (50%), Positives = 15/22 (68%)
 Frame = +1

Query: 337 TDFNFLMVLGKGSFGKVMLADR 358
           + F  L VLG+GSFG+V  + R
Sbjct: 214 SQFELLKVLGQGSFGRVFXSGR 279
>12786
          Length = 460

 Score = 54.7 bits (130), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 37/119 (31%), Positives = 53/119 (44%), Gaps = 22/119 (18%)
 Frame = -3

Query: 442 FYAAEISIGLFFLHKRGIIYRDLKLDNVMLDSEGHIKIADFGMCKEHMMD--GVTTRTFC 499
           FY  E+   +  LH  G+I+ DLK  N ML + G++K+ DFG+      D   V   +  
Sbjct: 398 FYWREMLRAVKALHNEGVIHSDLKPANFMLVA-GNLKLIDFGIANTLQQDKTSVLKDSRV 222

Query: 500 GTPDYIAPEIIAYQ--------------------PYGKSVDWWAYGVLLYEMLAGQPPF 538
           GTP Y++PE I                         G   D W+ G +LY M+ G+ PF
Sbjct: 221 GTPSYMSPEAIMAACDDSADDSMEEDGHRTKPKYKVGVRSDVWSLGCILYNMVYGRTPF 45
>29590
          Length = 320

 Score = 54.3 bits (129), Expect = 2e-07,   Method: Composition-based stats.
 Identities = 23/49 (46%), Positives = 28/49 (57%)
 Frame = +3

Query: 492 GVTTRTFCGTPDYIAPEIIAYQPYGKSVDWWAYGVLLYEMLAGQPPFDG 540
           G   R   GTPDY+APE++ Y+P     D W+ GVL Y ML    PF G
Sbjct: 36  GEDIRDIIGTPDYVAPEVLDYEPLSIQTDMWSLGVLSYVMLTACSPFVG 182
>04138
          Length = 800

 Score = 53.5 bits (127), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 27/106 (25%), Positives = 53/106 (50%), Gaps = 4/106 (3%)
 Frame = +1

Query: 451 LFFLHKRGIIYRDLKLDNVMLDSEGHIKIADFGMCKEHMMDGVTTRTFCG---TPDYIAP 507
           L+++H+  I++RD+K  N+++  +G +K+ADFG+ +   ++      +     T  Y  P
Sbjct: 52  LYYIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRVVTLWYRPP 231

Query: 508 E-IIAYQPYGKSVDWWAYGVLLYEMLAGQPPFDGEDEDELFQSIME 552
           E ++  + Y  ++D W  G ++ EM    P   G  E      I +
Sbjct: 232 ELLLGDRNYSTAIDQWGAGCIMAEMWTRNPIMQGTTEQNQLTLITQ 369
>26525
          Length = 455

 Score = 53.5 bits (127), Expect = 3e-07,   Method: Composition-based stats.
 Identities = 26/49 (53%), Positives = 38/49 (77%), Gaps = 1/49 (2%)
 Frame = +1

Query: 182 NLIPMDPN-GLSDPYVKLKLIPDPKNESKQKTKTIRSTLNPQWNESFTF 229
           +L P DP+ G  DPYVKL+L+P+ K+  K KT+ +R TLNP+++E+FTF
Sbjct: 1   DLPPRDPSLGGCDPYVKLQLLPEKKH--KCKTRVVRKTLNPKYDETFTF 141

 Score = 29.3 bits (64), Expect = 4.8,   Method: Composition-based stats.
 Identities = 12/19 (63%), Positives = 16/19 (84%)
 Frame = +2

Query: 180 AKNLIPMDPNGLSDPYVKL 198
           ++NL  MD +GLSDPYVK+
Sbjct: 398 SRNLPKMDISGLSDPYVKI 454
>11353
          Length = 454

 Score = 53.5 bits (127), Expect = 3e-07,   Method: Composition-based stats.
 Identities = 21/50 (42%), Positives = 28/50 (56%)
 Frame = +1

Query: 102 HKFKIHTYGSPTFCDHCGSLLYGLIHQGMKCDTCDMNVHKQCVINVPSLC 151
           H+F+ +TY +PT+CD C  LL+G    G  C  C  N H +C   VP  C
Sbjct: 142 HRFEKYTYTTPTYCDFCQQLLWGFSKTGTHCVDCGYNCHDKCQPLVPKTC 291

 Score = 48.5 bits (114), Expect = 8e-06,   Method: Composition-based stats.
 Identities = 19/59 (32%), Positives = 26/59 (44%)
 Frame = +1

Query: 37  HKFIARFFKQPTFCSHCTDFIWGFGKQGFQCQVCCFVVHKRCHEFVTFSCPGADKGPDT 95
           H+F    +  PT+C  C   +WGF K G  C  C +  H +C   V  +C       DT
Sbjct: 142 HRFEKYTYTTPTYCDFCQQLLWGFSKTGTHCVDCGYNCHDKCQPLVPKTCSKLKSVSDT 318
>00715
          Length = 1788

 Score = 53.1 bits (126), Expect = 4e-07,   Method: Compositional matrix adjust.
 Identities = 42/157 (26%), Positives = 68/157 (43%), Gaps = 27/157 (17%)
 Frame = +1

Query: 411 DRLYFVMEYVNGGDLMY----HIQQVGKFKEPQAVFYAAEISIGLFFLHKRGIIYRDLKL 466
           D  +  MEYV   +L      H Q +        +  A +++ GL +LH   I++ DLK 
Sbjct: 154 DGAWLAMEYVGPLNLQTILNDHQQDI---DSSMRLSLALQMARGLHYLHSINIVHLDLKP 324

Query: 467 DNVMLDSEGHIKIADFGMCKEHM----------------------MDGVTTRTFCGTPDY 504
            N +L  +  ++IADFG C +                        + G       GT  Y
Sbjct: 325 ANCLLTRDLKLRIADFGCCHQLTPTGLDMGEREGGMAGNELELTPVQGAWKNELAGTLAY 504

Query: 505 IAPEII-AYQPYGKSVDWWAYGVLLYEMLAGQPPFDG 540
            APE++   QP  +S D ++ G+ L++M   Q P++G
Sbjct: 505 RAPELLKGLQPSVRS-DVYSLGITLWQMCTRQGPYEG 612
>17975
          Length = 449

 Score = 52.8 bits (125), Expect = 4e-07,   Method: Compositional matrix adjust.
 Identities = 42/138 (30%), Positives = 73/138 (52%), Gaps = 4/138 (2%)
 Frame = +3

Query: 350 FGKVMLADRKGTEELYAIKILKKDVVIQDDDVECTMV--EKRVLALLDKPPFLTQLHSCF 407
           F  V LA    T E  A+K++ K    + D+V  + +  E R + L+  P  + +L+   
Sbjct: 6   FAVVKLARHVFTGEKVAVKVIDKT---KLDEVSRSHLFQEVRCMKLVQHPN-VVRLYEVI 173

Query: 408 QTVDRLYFVMEYVNGGDLM-YHIQQVGKFKEPQAVFYAAEISIGLFFLHKRGIIYRDLKL 466
            T  +LY ++E  +GGD+  Y ++  G  +E  A  Y  +I   + + HK  +++RDLK 
Sbjct: 174 DTQTKLYLILELGDGGDMYDYIMRHSGGLEEKLAKRYFRQIVEAISYCHKLHVVHRDLKP 353

Query: 467 DNVM-LDSEGHIKIADFG 483
           +NV+  +  G +K+ DFG
Sbjct: 354 ENVVFFEKPGLVKLTDFG 407
>01718
          Length = 959

 Score = 52.8 bits (125), Expect = 5e-07,   Method: Compositional matrix adjust.
 Identities = 46/199 (23%), Positives = 91/199 (45%), Gaps = 7/199 (3%)
 Frame = +3

Query: 345 LGKGSFGKVMLADRKGTEELYAIKILKKDVVIQDDDVECTMVEKRVLALLDKPPFLTQLH 404
           +G G F +V     + T ++ A+K+          +    + E ++L  L     L  + 
Sbjct: 171 IGAGFFSEVFKVTHRITGQVMALKM-----NTMTSNRHNMLREVQLLNRLQHANILRFMG 335

Query: 405 SCFQTVDRLYFVMEYVNGGDLMYHIQQVGK-FKEPQAVFYAAEISIGLFFLHKRGIIYRD 463
            C     +L+ + EY+  G+L   +++  +     Q +     ++ GL +LH    I+RD
Sbjct: 336 VCVHE-GQLHALTEYIPSGNLEQLLEKKDEELPWTQRIQLTLGLARGLDYLHSTRFIHRD 512

Query: 464 LKLDNVMLDSEG----HIKIADFGMCKEHMMDGVTTRTF--CGTPDYIAPEIIAYQPYGK 517
           L   N+++  E     H  IADFG+  + + D +        G+P ++APE++    Y +
Sbjct: 513 LTSKNILIRREDNHGYHAVIADFGLATK-IPDPLDKEKLPTVGSPYWMAPEVLNGHFYNE 689

Query: 518 SVDWWAYGVLLYEMLAGQP 536
             D ++ G+++ E+ A  P
Sbjct: 690 RADLFSVGIIMCEITARIP 746
>07291
          Length = 833

 Score = 52.4 bits (124), Expect = 6e-07,   Method: Compositional matrix adjust.
 Identities = 33/147 (22%), Positives = 68/147 (46%), Gaps = 5/147 (3%)
 Frame = +1

Query: 439 QAVFYAAEISIGLFFLHKRGIIYRDLKLDNVMLDSEGHIKIADFGMCKEHMMDGVTTRTF 498
           Q + +  +I+ G+ +L +  +++R+L   N ++  +G ++++D+G+          T   
Sbjct: 52  QLLDFGRQIADGMAYLQEVKVVHRNLAARNCIVTEDGRLQLSDYGVTGSLFPQSYYTADD 231

Query: 499 CGTPD---YIAPEIIAYQPYGKSVDWWAYGVLLYEMLA-GQPPFDGEDEDELFQSIME-H 553
               D   ++APE I    +    D WA+GV+L+E+L  G  P+   +   L   + E H
Sbjct: 232 SPARDLVKWMAPETIDNFHFSSKSDVWAFGVVLWELLTRGITPYPDVENSSLLPYLKEGH 411

Query: 554 NVSYPKSLSKEAVSICKGLMTKHPAKR 580
            +  PK   +    +      + P +R
Sbjct: 412 RMKKPKQSPEPVYEMMTACWNESPEQR 492
>19301
          Length = 712

 Score = 51.6 bits (122), Expect = 9e-07,   Method: Compositional matrix adjust.
 Identities = 47/149 (31%), Positives = 73/149 (48%), Gaps = 1/149 (0%)
 Frame = +2

Query: 336 LTDFNFLMVLGKGSFGKVMLADRKGTEELYAIKILKKDVVIQDDDVECTMVEKRVLALLD 395
           +TD  +L   G G+ G V L   K   E  A+K ++    I++ D+       R L  L+
Sbjct: 311 ITDLEWL---GSGAQGAVFLG--KLCAEEVAVKKVRD---IKETDI-------RNLRKLN 445

Query: 396 KPPFLTQLHSCFQTVDRLYFVMEYVNGGDLMYHIQQVGKFKEPQAVF-YAAEISIGLFFL 454
            P  ++    C Q       +MEY   G L Y + + GK   P  V  ++ +I+ G+ +L
Sbjct: 446 HPNIISFKGVCTQA-PCYCIIMEYCPYGQL-YEVLRDGKEIPPALVLDWSKQIASGMNYL 619

Query: 455 HKRGIIYRDLKLDNVMLDSEGHIKIADFG 483
           H   II+RDLK  NV++     +KI+DFG
Sbjct: 620 HSHKIIHRDLKSPNVLVAKNDVVKISDFG 706
>19361
          Length = 685

 Score = 51.6 bits (122), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 24/84 (28%), Positives = 42/84 (50%), Gaps = 9/84 (10%)
 Frame = -1

Query: 89  ADKGPDTDDPRSK---------HKFKIHTYGSPTFCDHCGSLLYGLIHQGMKCDTCDMNV 139
            +  P+ D+P            H FK+  +    +C+ C + ++GLI QG+KC  C +  
Sbjct: 382 VNSTPEEDEPEQSIDWTQYEKPHVFKVQNFNGLNWCELCANFMWGLIAQGVKCQDCGVQT 203

Query: 140 HKQCVINVPSLCGMDHTEKRGRIY 163
           HK+C   +P+ C M + +   R+Y
Sbjct: 202 HKKCSERMPNEC-MPNMKYVKRLY 134

 Score = 45.4 bits (106), Expect = 7e-05,   Method: Compositional matrix adjust.
 Identities = 19/52 (36%), Positives = 26/52 (50%)
 Frame = -1

Query: 35  KDHKFIARFFKQPTFCSHCTDFIWGFGKQGFQCQVCCFVVHKRCHEFVTFSC 86
           K H F  + F    +C  C +F+WG   QG +CQ C    HK+C E +   C
Sbjct: 322 KPHVFKVQNFNGLNWCELCANFMWGLIAQGVKCQDCGVQTHKKCSERMPNEC 167
>11780
          Length = 1713

 Score = 47.4 bits (111), Expect(2) = 2e-06,   Method: Compositional matrix adjust.
 Identities = 35/155 (22%), Positives = 72/155 (46%), Gaps = 2/155 (1%)
 Frame = +3

Query: 334 VKLTDFNFLMVLGKGSFGKVMLADRKGTEELYAIKILKKDVVIQDDDVECTMVEKRVLAL 393
           +   D      +GKG FG V     +G  +  AIK LK     +D   +  + E  V+  
Sbjct: 588 IAXQDLEIGEAIGKGDFGDVYKGMYRG--QPVAIKQLKD----KDRGEQSFLQEASVMTS 749

Query: 394 LDKPPFLTQLHSCFQTVDRLYFVMEYVNGGDLMYHIQQVGK--FKEPQAVFYAAEISIGL 451
           L     +  +       + ++ V E++  G+L+ +++  G+    +   + +A +    +
Sbjct: 750 LRHDNLVRLIGVVLG--ETIFLVTEFMGKGNLVEYLRSRGRSVITKKDQINFATDTCAAM 923

Query: 452 FFLHKRGIIYRDLKLDNVMLDSEGHIKIADFGMCK 486
            +L  + +++RDL   NV++  +G  K++DFG+ K
Sbjct: 924 EYLESKRLVHRDLAARNVLVHDDGKAKVSDFGLAK 1028

 Score = 23.1 bits (48), Expect(2) = 2e-06,   Method: Compositional matrix adjust.
 Identities = 15/63 (23%), Positives = 30/63 (47%), Gaps = 2/63 (3%)
 Frame = +1

Query: 520  DWWAYGVLLYEMLA-GQPPFDGEDEDELFQSIME-HNVSYPKSLSKEAVSICKGLMTKHP 577
            D W++G+LL+E+ + G+ P+      ++   +   + +  P+    E  SI K      P
Sbjct: 1120 DMWSFGILLWEIYSFGRVPYPRIPLTDVVMHVERGYRMEAPEGCPPEIYSIMKQAWELDP 1299

Query: 578  AKR 580
             +R
Sbjct: 1300 NER 1308
>30040
          Length = 652

 Score = 50.8 bits (120), Expect = 2e-06,   Method: Composition-based stats.
 Identities = 28/94 (29%), Positives = 50/94 (53%), Gaps = 2/94 (2%)
 Frame = -3

Query: 171 EKLHVTVRDAKNLIPMDPNGLSDPYVKLKLIPDPKNESKQKTKTIRSTLNPQWNESFTFK 230
           E+L V +  AK+L     +  +DP+V++ L+ + K   ++KT   R+++NP WNE+  F 
Sbjct: 617 ERLTVVLMKAKDLKMSTSHPSADPFVRVSLLVEGKKVKRKKTSVRRASINPVWNEALAFN 438

Query: 231 LKPSD--KDRRLSVEIWDWDRTTRNDFMGSLSFG 262
           + P++      L V + D D     D +G+   G
Sbjct: 437 V-PAEVLPKVTLEVSVLDHDLIGHGDVLGTCVLG 339
>20640
          Length = 1492

 Score = 50.8 bits (120), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 35/128 (27%), Positives = 60/128 (46%), Gaps = 4/128 (3%)
 Frame = +1

Query: 457 RGIIYRDLKLDNVMLDSEGHIKIADFGMCKE-HMMDGVTTRTFCGTPDYIAP-EIIAYQP 514
           RG ++RDL   N ++  +  +KI+DFG+ +  H +D          P    P E I Y  
Sbjct: 1   RGYVHRDLATRNCLVGHDLVVKISDFGLARSVHSVDYYRGSEHDAIPIRWMPLEAILYNK 180

Query: 515 YGKSVDWWAYGVLLYEMLA-GQPPFDGEDEDELFQSIMEHNV-SYPKSLSKEAVSICKGL 572
           +    D W++GV+L+E+ A    P+ G   +E+ + + E  V + P+        + K  
Sbjct: 181 FSTQSDVWSFGVVLWEIFAFALQPYYGLTHEEVVRFVKEGKVLACPERTPPPMYELMKQC 360

Query: 573 MTKHPAKR 580
             + PA R
Sbjct: 361 WHRRPATR 384
>16708
          Length = 1397

 Score = 49.3 bits (116), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 42/167 (25%), Positives = 78/167 (46%), Gaps = 10/167 (5%)
 Frame = -1

Query: 341  FLMVLGKGSFGKVMLADRKGTEELYAIKILKKDVVIQDDDVECTMVEKRVLALLDKPPFL 400
             L VLGKG FGKV  A    T E  A   LK  ++        ++ E   L  ++   +L
Sbjct: 1391 ILQVLGKGVFGKVYEARLLSTHEKAA---LKTSILCHH-----SLDEVEALGRIEGGFYL 1236

Query: 401  TQLHSCFQTV---DRLYFVMEYVNGGDLM-----YHIQQVG-KFKEPQAVF-YAAEISIG 450
             Q+   + T     ++  ++ +   G L      Y  +++  ++  P  V   A +    
Sbjct: 1235 AQMFGAWVTCLPFPKMNILLHFYEMGPLCNVYAHYKNKEMPIRWSNPAMVCCIAGQXVCA 1056

Query: 451  LFFLHKRGIIYRDLKLDNVMLDSEGHIKIADFGMCKEHMMDGVTTRT 497
            L  +H+ G+++ D+K DNV++D+ G+ K+ D+G+ + + +    T T
Sbjct: 1055 LEHIHELGVVHMDVKADNVLVDAHGNCKLTDYGIAQLYKVYPAPTET 915
>22804
          Length = 967

 Score = 49.3 bits (116), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 21/51 (41%), Positives = 28/51 (54%)
 Frame = -3

Query: 102 HKFKIHTYGSPTFCDHCGSLLYGLIHQGMKCDTCDMNVHKQCVINVPSLCG 152
           H+F+ +TY +PT+CD C  LL+G    G  C  C  N H +C   VP  C 
Sbjct: 830 HRFEKYTYTTPTYCDFCQQLLWGFSKTGTHCVDCGYNCHDKCQPLVPKTCS 678

 Score = 42.7 bits (99), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 17/50 (34%), Positives = 24/50 (48%)
 Frame = -3

Query: 37  HKFIARFFKQPTFCSHCTDFIWGFGKQGFQCQVCCFVVHKRCHEFVTFSC 86
           H+F    +  PT+C  C   +WGF K G  C  C +  H +C   V  +C
Sbjct: 830 HRFEKYTYTTPTYCDFCQQLLWGFSKTGTHCVDCGYNCHDKCQPLVPKTC 681
>30743
          Length = 569

 Score = 44.7 bits (104), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 18/39 (46%), Positives = 23/39 (58%)
 Frame = +2

Query: 106 IHTYGSPTFCDHCGSLLYGLIHQGMKCDTCDMNVHKQCV 144
           +HT+  P  CD CG LL G+  QG  C    M VHK+C+
Sbjct: 338 MHTFEKPKECDVCGKLLRGIFFQGYLCQDNQMAVHKECI 454

 Score = 30.4 bits (67), Expect = 2.4,   Method: Compositional matrix adjust.
 Identities = 14/40 (35%), Positives = 19/40 (47%)
 Frame = +2

Query: 39  FIARFFKQPTFCSHCTDFIWGFGKQGFQCQVCCFVVHKRC 78
           +I   F++P  C  C   + G   QG+ CQ     VHK C
Sbjct: 332 YIMHTFEKPKECDVCGKLLRGIFFQGYLCQDNQMAVHKEC 451
>20152
          Length = 445

 Score = 44.7 bits (104), Expect = 1e-04,   Method: Composition-based stats.
 Identities = 21/75 (28%), Positives = 38/75 (50%), Gaps = 1/75 (1%)
 Frame = +1

Query: 507 PEIIAYQPY-GKSVDWWAYGVLLYEMLAGQPPFDGEDEDELFQSIMEHNVSYPKSLSKEA 565
           PEI+    Y   +VD W+ GV+LY ++ G+ PF   ++ E    IM+     P  +S + 
Sbjct: 1   PEILLGDSYDAPAVDVWSLGVILYMLVVGEAPFQEANDSETLTMIMDCRYQIPPHISHKC 180

Query: 566 VSICKGLMTKHPAKR 580
             + + ++ + P  R
Sbjct: 181 QDLIEKMLQREPVDR 225
>27274
          Length = 396

 Score = 42.7 bits (99), Expect = 5e-04,   Method: Composition-based stats.
 Identities = 27/94 (28%), Positives = 52/94 (55%), Gaps = 5/94 (5%)
 Frame = -1

Query: 508 EIIAYQPYGKSVDWWAYGVLLYEMLAGQPPFDGE-DEDELFQSIMEHNVSYPKSLSKEAV 566
           E++  Q +G +VD W+ G+LL+E+L+G  PF+ E    ++ +++M     Y + +   + 
Sbjct: 375 ELLRGQQHGPTVDMWSLGILLHELLSGHVPFEPERGSRQMARNMM---AVYAQIIRGSSR 205

Query: 567 SICKGL-MTKHPA---KRLGCGPEGERDVREHAF 596
            +C GL ++ H A   +RL    + +R   + AF
Sbjct: 204 DVCDGLALSTHGADFLRRLVQLEDTKRLTSQQAF 103
>18996
          Length = 491

 Score = 42.0 bits (97), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 25/78 (32%), Positives = 41/78 (52%), Gaps = 4/78 (5%)
 Frame = +2

Query: 460 IYRDLKLDNVMLDSEGHIKIADFGMCKEHMMDG----VTTRTFCGTPDYIAPEIIAYQPY 515
           I+RDL   N+++D    +KI+DFG+ +    DG    ++ R       + +PE I    +
Sbjct: 2   IHRDLAARNILVD-RSCVKISDFGLAQFANADGYYYGISQRDI--PIKWYSPEAIETCKF 172

Query: 516 GKSVDWWAYGVLLYEMLA 533
               D W+YGV L+EM +
Sbjct: 173 SSYSDVWSYGVTLFEMFS 226
>02638
          Length = 1490

 Score = 41.6 bits (96), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 15/43 (34%), Positives = 28/43 (65%)
 Frame = +1

Query: 500 GTPDYIAPEIIAYQPYGKSVDWWAYGVLLYEMLAGQPPFDGED 542
           GT  ++APE++  + YG++ D W+ G ++ EM   +PP++  D
Sbjct: 22  GTIAFMAPEVLRGESYGRACDVWSVGCVMIEMCTCRPPWNSHD 150
>07836
          Length = 1478

 Score = 41.2 bits (95), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 36/140 (25%), Positives = 66/140 (47%), Gaps = 20/140 (14%)
 Frame = -1

Query: 412  RLYFVMEYVNGGDLM-YHIQQVGKFKEPQAVFYAAEISIGLFFLH--------KRGIIYR 462
            +L+ + +Y   G L  Y + +V    E  A+ ++A    GL  LH        K  I +R
Sbjct: 1331 QLFLITDYHENGSLHDYLLSRVLDSSEMLALAHSA--ICGLAHLHIEIFGTRGKPAIAHR 1158

Query: 463  DLKLDNVMLDSEGHIKIADFGMCKEHMMDG----VTTRTFCGTPDYIAPEIIA------- 511
            D+K  N+++   G   IAD G+   ++ +     V      GT  Y+APE++        
Sbjct: 1157 DIKSKNILVKKNGTCCIADLGLAVRYISESNEVDVAPNPRQGTKRYMAPEVLEMLLNVKN 978

Query: 512  YQPYGKSVDWWAYGVLLYEM 531
            +  + K  D +A+G++++E+
Sbjct: 977  FDAF-KQADMYAFGLVMWEI 921
>14477
          Length = 493

 Score = 40.4 bits (93), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 42/148 (28%), Positives = 67/148 (45%), Gaps = 6/148 (4%)
 Frame = -1

Query: 345 LGKGSFGKVM-----LADRKGTEELYAIKILKKDVVIQDDDVECTMV-EKRVLALLDKPP 398
           LG G+FG VM     L DR   E   AIK+LK   +  D  V+  ++ E  V+  +D   
Sbjct: 466 LGAGNFGSVMKGVCRLDDR---EIPVAIKVLKNADL--DPSVQSELIKEAEVMKKMDHMH 302

Query: 399 FLTQLHSCFQTVDRLYFVMEYVNGGDLMYHIQQVGKFKEPQAVFYAAEISIGLFFLHKRG 458
            +  +  C    + +  V+E    G L   + +         +    ++S G+ +L    
Sbjct: 301 IVRLIGLC--EGETMMLVLELAKLGPLNKFLPKNKHLPLWNILELMWQVSQGMEYLEANK 128

Query: 459 IIYRDLKLDNVMLDSEGHIKIADFGMCK 486
            ++RDL   N++L  E   KI+DFGM K
Sbjct: 127 FVHRDLAARNILLCDEHFAKISDFGMSK 44
>08294
          Length = 1849

 Score = 40.0 bits (92), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 35/182 (19%), Positives = 76/182 (41%), Gaps = 15/182 (8%)
 Frame = +2

Query: 414  YFVMEYVNGGDLMYHI------------QQVGKFKEPQAVFYAAEISIGLFFLHKRGIIY 461
            + + EY + GDL   +             +V      Q +    +++ G+  L  +G+++
Sbjct: 935  FLITEYCDWGDLKQFLLATRNDNGRGRGTRVPALALSQKLGMGQQVAAGMEALSNQGLVH 1114

Query: 462  RDLKLDNVMLDSEGHIKIADFGMCKE-HMMDGVTTRTFCGTPDYIAPEIIAYQPYGKSVD 520
             DL   NV+L S   +K+A   +  + +  +            ++ PE +         D
Sbjct: 1115 GDLAARNVLLTSRMQLKVARPALSGDVYASEYYPLHQRLVPLRWLPPEGVLEDSATTCGD 1294

Query: 521  WWAYGVLLYEMLA-GQPPFDGEDEDELFQSIMEHNVSYPKSLSKEA-VSICKGLMTKHPA 578
             WA+GV L+E+L     P+    ++E+ +S+     +     +  A +S+ +    + P+
Sbjct: 1295 VWAFGVFLWEVLQLADLPYRLMSDEEVLRSLQHSQAALDSPDAPPALLSLLQRCTAQQPS 1474

Query: 579  KR 580
            +R
Sbjct: 1475 QR 1480
>03942
          Length = 912

 Score = 40.0 bits (92), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 22/63 (34%), Positives = 35/63 (55%), Gaps = 3/63 (4%)
 Frame = +2

Query: 546 LFQSIMEHNVSYPKSLSKEAVSICKGLMTKHPAKRLGCGPE--GERDVREHAFF-RRIDW 602
           L+  ++ +  +Y   +   ++      MTK+PAKRLGC      E+ +  HAFF ++IDW
Sbjct: 29  LYMQVLCNEYAYLVYMFSMSLFCIFQFMTKNPAKRLGCVTSQGAEKAIFIHAFFHQKIDW 208

Query: 603 EKL 605
           E L
Sbjct: 209 EAL 217
>12442
          Length = 468

 Score = 39.7 bits (91), Expect = 0.004,   Method: Composition-based stats.
 Identities = 20/37 (54%), Positives = 25/37 (67%), Gaps = 3/37 (8%)
 Frame = +3

Query: 572 LMTKHPAKRLGC--GPEGERDVREHAFF-RRIDWEKL 605
            MTK+PAKRLGC      E+ +  HAFF ++IDWE L
Sbjct: 105 FMTKNPAKRLGCVTSQGAEKAIFIHAFFHQKIDWEAL 215
>36305
          Length = 586

 Score = 38.1 bits (87), Expect = 0.012,   Method: Compositional matrix adjust.
 Identities = 29/89 (32%), Positives = 42/89 (47%), Gaps = 4/89 (4%)
 Frame = -1

Query: 190 GLSDPYVKLKLIPDPKNESKQKTKTIRSTLNPQWNESFTFKLKPSDKDRRLSVEIWDWDR 249
           G SDPY  + +          KTK I  T+ P+WNE F F +   D  + L + I D D 
Sbjct: 583 GKSDPYTVVTV-----GAQTFKTKVIDDTVEPRWNEVFEFVIDERDG-QILKLNISDKDP 422

Query: 250 TTRNDFMGSLSFGVSEL----MKMPASGW 274
             ++D +GS +  +S +    M M  S W
Sbjct: 421 GNKDDPLGSTTMDISTIFEKAMWMSGSPW 335
>11404
          Length = 563

 Score = 38.1 bits (87), Expect = 0.012,   Method: Compositional matrix adjust.
 Identities = 36/134 (26%), Positives = 62/134 (46%), Gaps = 6/134 (4%)
 Frame = +1

Query: 344 VLGKGSFGKVMLADRKGTEELYAIKILK-KDVVIQDDDVECTMVEKRVLALLDKPPFLTQ 402
           ++GKGSFG+V+ A      E  AIKI+K K   +    +E  ++E       D   ++ +
Sbjct: 160 LIGKGSFGQVVKAYDHTDNEQVAIKIIKNKKPFLNQAQIEVKLLEMMNRHDTDNKYYIVR 339

Query: 403 LHSCFQTVDRLYFVMEYVNGGDLMYHIQQVGKFKEPQAVF---YAAEISIGLFFLH--KR 457
           L   F     L  V E ++    +Y + +   F+         +A ++   L FL   + 
Sbjct: 340 LKRHFMFRSHLCLVFELLSYN--LYDLLRNTNFRGVSLNLTRKFAQQLCTALLFLATPEM 513

Query: 458 GIIYRDLKLDNVML 471
            II+ DLK +N++L
Sbjct: 514 SIIHCDLKPENILL 555
>22005
          Length = 873

 Score = 38.1 bits (87), Expect = 0.013,   Method: Compositional matrix adjust.
 Identities = 27/102 (26%), Positives = 47/102 (46%), Gaps = 2/102 (1%)
 Frame = +1

Query: 433 GKFKEPQAVFYAAEISIGLFFLHKRGIIYRDLKLDNVMLDSEGHIKIADFGMCKE-HMMD 491
           G       ++ + +IS G+ +L ++  ++RDL    V         I+DFG+ +  H +D
Sbjct: 427 GMLXTKDQLYISQQISAGMAYLAQKDYVHRDLATRTVXS-RTT*S*ISDFGLARSVHSVD 603

Query: 492 GVTTRTFCGTPDYIAP-EIIAYQPYGKSVDWWAYGVLLYEML 532
                     P    P E I Y  +    D W++GV+L+E+L
Sbjct: 604 YYRGSEQDAIPIRWMPLEAILYSKFSTQSDVWSFGVVLWEIL 729
>31120
          Length = 439

 Score = 36.6 bits (83), Expect = 0.030,   Method: Composition-based stats.
 Identities = 24/78 (30%), Positives = 38/78 (48%), Gaps = 5/78 (6%)
 Frame = +1

Query: 508 EIIAYQPYG-KSVDWWAYGVLLYEMLAGQPPFDGEDEDELFQSIMEHNVSYPKSL----S 562
           E++   PY  K  D W+ GV+L+ ML G+ PFD  + ++L +       S+ + L    S
Sbjct: 1   EVVCGVPYDPKMADAWSLGVILFIMLNGKMPFDDSNLNKLLEDQRSKKYSFRRKLQDLVS 180

Query: 563 KEAVSICKGLMTKHPAKR 580
             A S    L+  + A R
Sbjct: 181 PNARSTVSVLLEPNSAMR 234
>26304
          Length = 1290

 Score = 36.6 bits (83), Expect = 0.033,   Method: Compositional matrix adjust.
 Identities = 27/85 (31%), Positives = 42/85 (49%), Gaps = 10/85 (11%)
 Frame = +3

Query: 193 DPYVKLKLIPD------PKNESKQKTKTIRSTLNPQW-NESFTFKLKPSDKDRRLSVEIW 245
           DPYVKL ++P       P +  + ++    ST NP W NE+FT +   +D    + +EI 
Sbjct: 906 DPYVKLTVVPSKSYPEKPHHHRELRSSVCPSTTNPVWDNETFTLEAYVTD---LVELEIK 1076

Query: 246 D---WDRTTRNDFMGSLSFGVSELM 267
           D     R T + F+G +   V  +M
Sbjct: 1077DKFSKSRPTMSRFLGKVVIAVQRIM 1151
>13896
          Length = 827

 Score = 35.4 bits (80), Expect = 0.083,   Method: Compositional matrix adjust.
 Identities = 20/50 (40%), Positives = 29/50 (58%)
 Frame = +2

Query: 176 TVRDAKNLIPMDPNGLSDPYVKLKLIPDPKNESKQKTKTIRSTLNPQWNE 225
           TV  A+NLI    +G +D YV ++L      + K +T TIR+  NP+W E
Sbjct: 167 TVLRARNLISKGKSGNNDVYVTIQL-----GKEKYQTSTIRNAHNPEWFE 301
>17253
          Length = 483

 Score = 35.0 bits (79), Expect = 0.093,   Method: Composition-based stats.
 Identities = 24/115 (20%), Positives = 49/115 (42%), Gaps = 15/115 (13%)
 Frame = -1

Query: 387 EKRVLALLDKPPFLTQLHSCFQTVDRLYFVMEYVNGGDLMYHIQQVGKFKEPQAVF---- 442
           E  ++  L + P +     C    D    +ME+   GDL+  ++   K +  + VF    
Sbjct: 399 ELSIMRKLPRHPNVVSFMGCCTMSDPALILMEFCCHGDLLSFLR---KRRPDRTVFLTST 229

Query: 443 -----------YAAEISIGLFFLHKRGIIYRDLKLDNVMLDSEGHIKIADFGMCK 486
                      +A  ++ G+  +    I++RD+   NV++      K++DFG+ +
Sbjct: 228 ANDLTARDFFSFALHVARGMAHVANNKIVHRDVAARNVLISERNVCKVSDFGLSR 64
>13155
          Length = 663

 Score = 35.0 bits (79), Expect = 0.10,   Method: Compositional matrix adjust.
 Identities = 33/134 (24%), Positives = 60/134 (44%), Gaps = 24/134 (17%)
 Frame = -2

Query: 168 VTDEKLHVTVRDAKNLIPMDPNGLSDPYVKLKLIPDP-KNESKQKTKTIRSTLNPQWNES 226
           ++  ++ V V +  +L  +  NG  +PY  + L+    KN   ++T   + T+ PQ++E 
Sbjct: 419 ISSHRMTVRVTECSDLRII--NGACNPYAVVTLLWGKYKNREVRRTAVRKKTICPQFDEV 246

Query: 227 FTFKL--KPSDKDR-----------RLSVEIW-DWDRTTR--------NDFMGSLSFGVS 264
           F+F L  +  ++DR            LSV  W D  R +R          F+G +   + 
Sbjct: 245 FSFDLNNRGQNQDRNNYSFDDVYEGELSVSXWHDDSRVSREVLGNMFPGSFLGEVKIALR 66

Query: 265 EL-MKMPASGWYKL 277
           +L +    + WY L
Sbjct: 65  DLDLATAHTAWYCL 24
>29360
          Length = 363

 Score = 34.3 bits (77), Expect = 0.16,   Method: Compositional matrix adjust.
 Identities = 33/119 (27%), Positives = 56/119 (47%), Gaps = 5/119 (4%)
 Frame = +3

Query: 358 RKGTEELYAIKILKKD-VVIQDDDVECTMVEKRVLALLDKPPFLTQLHSCFQTVDRLYFV 416
           +KGT E+ AIKILK      +   +E +++++      D   F+     CFQ  +    V
Sbjct: 15  KKGTSEIVAIKILKNHPSYARQGQIEVSILQRLSQESADDYNFVRAF-ECFQHKNHTCLV 191

Query: 417 MEYVNGGDLMYHIQQVGKFKEPQAVFY----AAEISIGLFFLHKRGIIYRDLKLDNVML 471
            E +     +Y   +  KF +P  + Y      ++   L  L + G+I+ DLK +N+ML
Sbjct: 192 FEMLEQN--LYDFLKQNKF-QPLPLKYIRPITQQVLTALRKLKQLGLIHADLKPENIML 359
>18401
          Length = 463

 Score = 33.9 bits (76), Expect = 0.22,   Method: Compositional matrix adjust.
 Identities = 20/70 (28%), Positives = 33/70 (47%), Gaps = 1/70 (1%)
 Frame = -3

Query: 497 TFCGTPDYIAPEIIAYQPYGKSVDWWAYGVLLYEMLAGQPPFDGEDEDELFQSIMEHNV- 555
           T   T  Y APE+I    +    D W+ G +++E+  G   F   D  E   ++ME  + 
Sbjct: 455 TIVSTRHYRAPEVILELGWSHPCDVWSVGCIMFELYTGYTLFQTHDNKEHL-AMMERILG 279

Query: 556 SYPKSLSKEA 565
           S P  ++K+ 
Sbjct: 278 SLPYRMAKKT 249
>23319
          Length = 2235

 Score = 33.5 bits (75), Expect = 0.28,   Method: Compositional matrix adjust.
 Identities = 15/47 (31%), Positives = 27/47 (57%), Gaps = 1/47 (2%)
 Frame = +3

Query: 507 PEIIAYQPYGKSVDWWAYGVLLYEML-AGQPPFDGEDEDELFQSIME 552
           P++   + Y  S+D W+ G +  E+  AG+P F G D+D+  + I +
Sbjct: 3   PDVYXAKMYSTSIDMWSAGCIFAELANAGRPLFPGNDDDDQLKRIFK 143
>02913
          Length = 855

 Score = 33.1 bits (74), Expect = 0.36,   Method: Compositional matrix adjust.
 Identities = 16/42 (38%), Positives = 26/42 (61%)
 Frame = +3

Query: 626 FDKFFTRGQPVLTPPDQLVIANIDQSDFEGFSYVNPQFVHPI 667
           FD  FTR  PV +P D ++  +I+Q  F+GF+Y+ P  +  +
Sbjct: 18  FDTKFTRQTPVDSPDDTILSDSINQV-FKGFTYIAPSVLEEV 140
>17516
          Length = 453

 Score = 32.7 bits (73), Expect = 0.45,   Method: Composition-based stats.
 Identities = 15/44 (34%), Positives = 25/44 (56%), Gaps = 1/44 (2%)
 Frame = -3

Query: 497 TFCGTPDYIAPEIIAYQ-PYGKSVDWWAYGVLLYEMLAGQPPFD 539
           T  GTP Y+APE++  +  Y    D ++  ++L+E+  GQ   D
Sbjct: 442 TLAGTPVYMAPEVLLQKGQYDMKADVYSLAIILWELWYGQDAAD 311
>17932
          Length = 597

 Score = 32.7 bits (73), Expect = 0.50,   Method: Composition-based stats.
 Identities = 19/54 (35%), Positives = 28/54 (51%), Gaps = 2/54 (3%)
 Frame = -2

Query: 521 WWAYGVLLYEMLAGQPPFDGEDEDEL--FQSIMEHNVSYPKSLSKEAVSICKGL 572
           WW+ GV  YEML G  PF  +D   +  + +IM +  +   S S++ V    GL
Sbjct: 596 WWSLGVCAYEMLFGCTPFTDDDGSMVATYNNIMNYKTN-SSSPSQQRVQRGAGL 438

 Score = 32.3 bits (72), Expect = 0.61,   Method: Composition-based stats.
 Identities = 22/70 (31%), Positives = 37/70 (52%)
 Frame = -3

Query: 549 SIMEHNVSYPKSLSKEAVSICKGLMTKHPAKRLGCGPEGERDVREHAFFRRIDWEKLENR 608
           +I +  V    S+SKEA  +   L++   + RLG  PE    +++H FF+ +DW  + N 
Sbjct: 496 TIRQTQVPPHSSVSKEARDLISQLLSDGKS-RLGW-PE----LQQHPFFKTVDWANIRN- 338

Query: 609 EIQPPFKPKV 618
              PP+ P +
Sbjct: 337 -AMPPYVPSI 311
>01494
          Length = 2122

 Score = 31.6 bits (70), Expect = 0.96,   Method: Compositional matrix adjust.
 Identities = 28/93 (30%), Positives = 47/93 (50%), Gaps = 2/93 (2%)
 Frame = +1

Query: 173  LHVTVRDAKNLIPMDPNGLSDPYVKLKLIPDPKNESKQKTKT-IRSTLNPQWNESFTFK- 230
            L +T+  A++L+     G++ P+V++++     +  K KT T + + LNP WNE+  F  
Sbjct: 1165 LTLTIVGARHLVK-SGRGIASPFVEIEVTGXECDNQKFKTGTRVDNGLNPVWNENCVFDV 1341

Query: 231  LKPSDKDRRLSVEIWDWDRTTRNDFMGSLSFGV 263
            L P     R +V   D D     +F+G   F V
Sbjct: 1342 LCPEMALLRFAV--MDEDIFGDPNFLGQAXFPV 1434
>02841
          Length = 1442

 Score = 31.2 bits (69), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 14/34 (41%), Positives = 22/34 (64%)
 Frame = -1

Query: 636 VLTPPDQLVIANIDQSDFEGFSYVNPQFVHPILQ 669
           +L P +   +A ID +DF GF++ +P FV P+ Q
Sbjct: 740 ILAPFNXTTVAFIDVADFVGFAFSSPVFV-PVFQ 642
>26009
          Length = 886

 Score = 31.2 bits (69), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 18/50 (36%), Positives = 30/50 (60%), Gaps = 1/50 (2%)
 Frame = +2

Query: 324 RKQPSNNLDRVKLTD-FNFLMVLGKGSFGKVMLADRKGTEELYAIKILKK 372
           R   S+NL  + L + ++    LG+G++GKV+LA  + T    A+K+L K
Sbjct: 374 RNSTSDNLLTLSLREHYDVCKELGRGTYGKVVLARCRHTGTQVALKLLPK 523
>26052
          Length = 562

 Score = 30.8 bits (68), Expect = 1.8,   Method: Composition-based stats.
 Identities = 15/28 (53%), Positives = 17/28 (60%)
 Frame = -1

Query: 341 FLMVLGKGSFGKVMLADRKGTEELYAIK 368
           F  +LG GSFGKVM    K T E  A+K
Sbjct: 379 FXKLLGVGSFGKVMALQHKDTGETLAVK 296
>13305
          Length = 549

 Score = 30.8 bits (68), Expect = 2.0,   Method: Composition-based stats.
 Identities = 14/45 (31%), Positives = 24/45 (53%), Gaps = 1/45 (2%)
 Frame = +2

Query: 504 YIAPEIIAYQPYGKSVDWWAYGVLLYEMLA-GQPPFDGEDEDELF 547
           ++A E +    Y    D W++GV+L+E+   G  P+   D  +LF
Sbjct: 23  WMAVESLFNNTYTTQSDVWSFGVVLWEIFTLGGTPYSSTDTQQLF 157
>16300
          Length = 766

 Score = 30.4 bits (67), Expect = 2.2,   Method: Compositional matrix adjust.
 Identities = 27/96 (28%), Positives = 39/96 (40%), Gaps = 11/96 (11%)
 Frame = -2

Query: 90  DKGPDTDDPRSKHKFKIHTYGSPTFCDHCGSLLYGLIHQGMKCDTCDMNVHKQCVINVPS 149
           ++G   +D  S H   +   GSPTFC   GSL +      +    CD ++       V S
Sbjct: 432 NQGKVIEDFISDHSLCLLNTGSPTFCASSGSLTH------VDLSICDPSLFLDLEWQVHS 271

Query: 150 -LCGMDH----------TEKRGRIYLKAEVTDEKLH 174
            LCG DH          TE+  R + K    +  L+
Sbjct: 270 DLCGSDHFPILTSFKKKTEESCREFWKFRAANWSLY 163
>18481
          Length = 437

 Score = 30.0 bits (66), Expect = 3.2,   Method: Compositional matrix adjust.
 Identities = 16/41 (39%), Positives = 25/41 (60%), Gaps = 3/41 (7%)
 Frame = -1

Query: 451 LFFLHKRGIIYRDLKLDNVMLDSEGH---IKIADFGMCKEH 488
           L F+H++  I+RDLK DN ++    H   + I DFG+ K +
Sbjct: 158 LEFIHQKCFIHRDLKPDNFLMGLGRHCHRLYIIDFGLSKRY 36
>17357
          Length = 482

 Score = 30.0 bits (66), Expect = 3.2,   Method: Composition-based stats.
 Identities = 13/34 (38%), Positives = 21/34 (61%)
 Frame = +2

Query: 246 DWDRTTRNDFMGSLSFGVSELMKMPASGWYKLLN 279
           DWDR T+N+ +G L  GV +     A+ W +++N
Sbjct: 2   DWDRMTKNEVVGRLEIGV-KCGGQEANHWNEVIN 100
>33692
          Length = 426

 Score = 29.6 bits (65), Expect = 3.8,   Method: Composition-based stats.
 Identities = 13/31 (41%), Positives = 15/31 (48%), Gaps = 1/31 (3%)
 Frame = -1

Query: 50  CSHCTDFIWGFGKQGFQCQVCC-FVVHKRCH 79
           C +     WG   QGFQC  CC +VV    H
Sbjct: 228 CRNLLSSFWGKVSQGFQCLNCCWYVVRNTLH 136
>36388
          Length = 834

 Score = 29.3 bits (64), Expect = 5.4,   Method: Compositional matrix adjust.
 Identities = 14/31 (45%), Positives = 18/31 (58%), Gaps = 4/31 (12%)
 Frame = +2

Query: 58  WGFGKQGFQCQVCCFVVHK--RCH--EFVTF 84
           WG+G   F+C++CCF  H    CH   F TF
Sbjct: 257 WGWGDHNFKCRICCFQFHWVLSCHLXXFQTF 349
>17637
          Length = 447

 Score = 29.3 bits (64), Expect = 5.8,   Method: Compositional matrix adjust.
 Identities = 19/79 (24%), Positives = 39/79 (49%), Gaps = 2/79 (2%)
 Frame = +1

Query: 504 YIAPEIIAYQPYGKSVDWWAYGVLLYEMLA-GQPPFDGEDEDELFQSIME-HNVSYPKSL 561
           +++ E +    Y +  D W++GVL++EM   G+ P+   D  E+   + + + ++ P + 
Sbjct: 115 WLSLEALQKSHYNEGSDVWSFGVLMWEMCTLGKLPYAEIDPYEMEHYLKDGYRLAQPFNC 294

Query: 562 SKEAVSICKGLMTKHPAKR 580
             E  +I        PA+R
Sbjct: 295 PDELFTIMAYCWASMPAER 351
>18567
          Length = 437

 Score = 28.9 bits (63), Expect = 6.8,   Method: Compositional matrix adjust.
 Identities = 22/62 (35%), Positives = 26/62 (41%), Gaps = 8/62 (12%)
 Frame = -3

Query: 84  FSCPGADKGPDTDDPRSKHKFKIHTYGSPTFCDHCGSLL--------YGLIHQGMKCDTC 135
           F C   +KG    +   KHKF IHT   P  CD C            + LIH   KC  C
Sbjct: 198 FVCDVCEKGFTLRENLIKHKF-IHTGQKPFVCDVCHKSFTQKYNLDQHKLIHSDQKCYVC 22

Query: 136 DM 137
           D+
Sbjct: 21  DV 16
>00638
          Length = 1595

 Score = 28.5 bits (62), Expect = 8.3,   Method: Compositional matrix adjust.
 Identities = 17/51 (33%), Positives = 24/51 (47%)
 Frame = +2

Query: 415 FVMEYVNGGDLMYHIQQVGKFKEPQAVFYAAEISIGLFFLHKRGIIYRDLK 465
            + E+VN  D     Q    F +    FY  E+   L F H  GI++RD+K
Sbjct: 356 LIFEHVNNTDFK---QLYQTFTDYDIRFYLYELMKALDFCHSMGIMHRDVK 499
>32359
          Length = 928

 Score = 28.5 bits (62), Expect = 9.2,   Method: Compositional matrix adjust.
 Identities = 17/42 (40%), Positives = 22/42 (52%)
 Frame = -1

Query: 332 DRVKLTDFNFLMVLGKGSFGKVMLADRKGTEELYAIKILKKD 373
           DR +   +    V+G GSFG V  A    T EL AIK + +D
Sbjct: 445 DRPQEVSYTDAKVIGNGSFGVVYQAKLVDTSELVAIKKVLQD 320
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31542413|ref|NP_035909.2| coronin, actin binding
protein 1C [Mus musculus]
         (474 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

16105                                                                 337   4e-93
30679                                                                 199   4e-60
03387                                                                  67   2e-11
01805                                                                  58   1e-08
01768                                                                  57   1e-08
19498                                                                  56   2e-08
19949                                                                  52   5e-07
12140                                                                  48   1e-05
30108                                                                  42   4e-04
02960                                                                  42   5e-04
31474                                                                  42   6e-04
12841                                                                  41   8e-04
10264                                                                  40   0.001
29912                                                                  40   0.002
00825                                                                  40   0.002
01598                                                                  40   0.002
27475                                                                  39   0.004
37180                                                                  38   0.007
12574                                                                  38   0.009
37142                                                                  38   0.010
31384                                                                  38   0.010
21921                                                                  38   0.011
27465                                                                  37   0.012
04358                                                                  37   0.022
06576                                                                  37   0.023
28289                                                                  36   0.036
30256                                                                  36   0.036
14516                                                                  35   0.061
17602                                                                  35   0.068
13335                                                                  35   0.096
03156                                                                  34   0.12 
02147                                                                  34   0.12 
01327                                                                  34   0.12 
18981                                                                  34   0.12 
15745                                                                  33   0.20 
04088                                                                  32   0.38 
05642                                                                  32   0.44 
31864                                                                  32   0.45 
03395                                                                  32   0.57 
19863                                                                  30   1.5  
14500                                                                  30   1.9  
15118                                                                  29   4.4  
27681                                                                  29   4.7  
26107                                                                  29   5.0  
25880                                                                  28   6.9  
05303                                                                  28   7.1  
38362                                                                  28   7.2  
>16105
          Length = 960

 Score =  337 bits (865), Expect = 4e-93,   Method: Compositional matrix adjust.
 Identities = 155/269 (57%), Positives = 203/269 (75%)
 Frame = -2

Query: 5   VRQSKFRHVFGQAVKNDQCYDDIRVSRVTWDSSFCAVNPRFVAIIIEASGGGAFLVLPLH 64
           +RQSKFRHVFG+  K DQCYD IR++R +W+S++CAVNP+FVA++ EA+GGGAFLVLPL 
Sbjct: 800 MRQSKFRHVFGKPEKRDQCYDGIRITRTSWESTYCAVNPKFVAVMTEAAGGGAFLVLPLS 621

Query: 65  KTGRIDKSYPTVCGHTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLTLSLTEPVV 124
           + GR+    P V GH G VLDI WCPHND VIAS S+DCTV VWQIP++GL  +LT+PVV
Sbjct: 620 RVGRVPVDNPLVAGHKGAVLDIQWCPHNDNVIASASDDCTVKVWQIPDSGLVTNLTDPVV 441

Query: 125 ILEGHSKRVGIVAWHPTARNVLLSAGCDNAIIIWNVGTGEALINLDDMHSDMIYNVSWSR 184
            L GH KR  ++ WHP+A+NVL+SAG DN I+ WNVGTGE ++ +D    DMIY +S++ 
Sbjct: 440 DLVGHQKRCCLIVWHPSAQNVLVSAGADNKILFWNVGTGEPMLEVD--VPDMIYCMSFNF 267

Query: 185 NGSLICTASKDKKVRVIDPRKQEIVAEKEKAHEGARPMRAIFLADGNVFTTGFSRMSERQ 244
           NGS +    KDKK+R+ID     ++ E  K H+GA+P +A +L DG VFTTGFSRMSERQ
Sbjct: 266 NGSRLVCTCKDKKLRIIDSHSGAVLKEG-KCHDGAKPAQACYLKDGKVFTTGFSRMSERQ 90

Query: 245 LALWNPKNMQEPIALHEMDTSNGVLLPFY 273
            A+W+  ++ E + L E+D+SNGV+  FY
Sbjct: 89  YAIWDENDLSESMTLEEIDSSNGVMFIFY 3
>30679
          Length = 1025

 Score =  199 bits (505), Expect(3) = 4e-60,   Method: Compositional matrix adjust.
 Identities = 89/192 (46%), Positives = 130/192 (67%)
 Frame = +1

Query: 144 NVLLSAGCDNAIIIWNVGTGEALINLDDMHSDMIYNVSWSRNGSLICTASKDKKVRVIDP 203
           N+LLSAG D   ++WNV   E  +N+ D H+D I+++SW+R GS+  T SKDKK+R IDP
Sbjct: 1   NILLSAGFDYKCVVWNVEQAEP-VNIVDCHTDTIFSMSWNRXGSMFATTSKDKKLRTIDP 177

Query: 204 RKQEIVAEKEKAHEGARPMRAIFLADGNVFTTGFSRMSERQLALWNPKNMQEPIALHEMD 263
           R   + AE +  H+G +  + +F  +  + TTGF++M  R+L+LW+ +  +  I   ++D
Sbjct: 178 RTTTVAAESQ-CHKGPKASKVVFADNVKLTTTGFAQMGSRELSLWDLRKSKTAIHTVDLD 354

Query: 264 TSNGVLLPFYDPDTSIIYLCGKGDSSIRYFEITDESPYVHYLNTFSSKEPQRGMGYMPKR 323
           +S GV+LP+YD DT +I+L GKGD +IRYFE++D     H+LN + S  PQRG+G MPKR
Sbjct: 355 SSCGVMLPYYDYDTRVIFLAGKGDGNIRYFEVSDTDSCFHFLNAYQSPSPQRGLGMMPKR 534

Query: 324 GLDVNKCEIARF 335
           G D  +CEI RF
Sbjct: 535 GCDTKRCEIMRF 570

 Score = 39.3 bits (90), Expect(3) = 4e-60,   Method: Compositional matrix adjust.
 Identities = 22/65 (33%), Positives = 30/65 (46%)
 Frame = +3

Query: 362 YPDTAGPEAALEAEEWFEGKNADPILISLKHGYIPGKNRDLKVVKKNILDSKPAANKKSE 421
           YP TA    +L A+EW  G+N +PIL+S+  G +        V    I  SK    +   
Sbjct: 654 YPPTASTIPSLRADEWISGQNREPILVSMVDGTV--------VSSPQITTSKAVQKQDGT 809

Query: 422 LSCAP 426
           L  AP
Sbjct: 810 LQSAP 824

 Score = 32.7 bits (73), Expect(3) = 4e-60,   Method: Compositional matrix adjust.
 Identities = 16/28 (57%), Positives = 19/28 (67%), Gaps = 2/28 (7%)
 Frame = +2

Query: 336 FKLHERK--CEPIIMTVPRKSDLFQDDL 361
            +LH  K   EPI M VPRKSD FQ+D+
Sbjct: 569 LQLHAAKNLVEPISMIVPRKSDAFQEDV 652
>03387
          Length = 1891

 Score = 67.0 bits (162), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 49/234 (20%), Positives = 106/234 (45%), Gaps = 4/234 (1%)
 Frame = +1

Query: 22  QCYDDIRVSRVTWDSSFCAVNPRFVAIIIEASGGGAFLVLPLHKT---GRIDKSYPTVCG 78
           +C  ++R+     +    + NP     ++ AS      +  ++ T    R+  ++    G
Sbjct: 328 ECIPELRLKGHQKEGYGLSWNPNLNGHLLSASDDHTICLWDINSTQRESRVVDAHTIFTG 507

Query: 79  HTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLTLSLTEPVVILEGHSKRVGIVAW 138
           HT  V D+ W   ++ +  S ++D  +M+W    N    + ++P  +++ H+  V  +++
Sbjct: 508 HTSVVEDVAWHLLHESLFGSVADDQKLMIWDTRSN----TTSKPSHVVDAHTAEVNCLSF 675

Query: 139 HPTARNVLLSAGCDNAIIIWNVGTGEALINLDDMHSDMIYNVSWS-RNGSLICTASKDKK 197
           +P +  +L +   D  + +W++   +  ++  + H D I+ V WS  N +++ ++  D++
Sbjct: 676 NPYSEFILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRR 855

Query: 198 VRVIDPRKQEIVAEKEKAHEGARPMRAIFLADGNVFTTGFSRMSERQLALWNPK 251
           + V D  K       E A +G  P   +F+  G+  T   S  S      WNP 
Sbjct: 856 LHVWDLSKIGEEQLPEDAEDG--PPELLFIHGGH--TAKISDFS------WNPN 987

 Score = 44.7 bits (104), Expect = 9e-05,   Method: Compositional matrix adjust.
 Identities = 23/91 (25%), Positives = 42/91 (46%), Gaps = 8/91 (8%)
 Frame = +1

Query: 79  HTGPVLDIDWCPHNDQVIASGSEDCTVMVW--------QIPENGLTLSLTEPVVILEGHS 130
           H   +  + W PHN+ ++AS   D  + VW        Q+PE+       E + I  GH+
Sbjct: 778 HKDEIFQVQWSPHNETILASSGTDRRLHVWDLSKIGEEQLPEDAED-GPPELLFIHGGHT 954

Query: 131 KRVGIVAWHPTARNVLLSAGCDNAIIIWNVG 161
            ++   +W+P    ++ S   DN + +W + 
Sbjct: 955 AKISDFSWNPNEPWIVCSVSEDNIMQVWQMA 1047

 Score = 36.2 bits (82), Expect = 0.028,   Method: Compositional matrix adjust.
 Identities = 15/36 (41%), Positives = 21/36 (58%)
 Frame = +1

Query: 78  GHTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPEN 113
           GHT  + D  W P+   ++ S SED  + VWQ+ EN
Sbjct: 946 GHTAKISDFSWNPNEPWIVCSVSEDNIMQVWQMAEN 1053
>01805
          Length = 2124

 Score = 57.8 bits (138), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 29/91 (31%), Positives = 45/91 (49%)
 Frame = -1

Query: 75  TVCGHTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLTLSLTEPVVILEGHSKRVG 134
           +V GHT  VLD+ W  +   V+AS S D TV +W + E  + ++ T+       HS+ V 
Sbjct: 591 SVTGHTQAVLDLSWNRNARHVLASASADTTVALWDLSEGKMAMNFTQ-------HSREVQ 433

Query: 135 IVAWHPTARNVLLSAGCDNAIIIWNVGTGEA 165
              WHP     LL+   DN + + +  + E 
Sbjct: 432 CCNWHPQEEQTLLTGSFDNTVKVVDCRSAET 340
>01768
          Length = 1424

 Score = 57.4 bits (137), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 38/156 (24%), Positives = 74/156 (47%), Gaps = 8/156 (5%)
 Frame = +3

Query: 55  GGAFLVLPLHKTGRIDKSYPTVCGHTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPENG 114
           G  ++  P       +KS  +   HT  V D+ W P+   V AS S D T+ +W   +  
Sbjct: 768 GAIYISQPSSSGWTTEKS--SYAAHTDSVEDVQWSPNEGNVFASCSVDRTLRIWNTQQKP 941

Query: 115 LTLSLTEPVVILEGHSKRVGIVAWHPTARNVLLSAGCDNAIIIWNVG-------TGEALI 167
              S    + + E HS+ + ++ W+P  +++L S G D  I IW++        + +A  
Sbjct: 942 ---SKANVLTVPEAHSRDINVINWNPIEKHLLASGGDDGIIKIWDLRMFRNKPVSAQASF 1112

Query: 168 NLDDMHSDMIYNVSWS-RNGSLICTASKDKKVRVID 202
            L   HS  + ++ W+ ++ S++  + +D ++ + D
Sbjct: 1113KL---HSQPVTSLEWNPQDSSVLAASGEDDQITIWD 1211
>19498
          Length = 903

 Score = 56.2 bits (134), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 42/132 (31%), Positives = 60/132 (45%), Gaps = 10/132 (7%)
 Frame = -1

Query: 79  HTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPEN-GLTLSLTEPVVILE---------G 128
           H G V  + W   N + +ASG +D  +M+WQI    G   S    V ILE         G
Sbjct: 789 HLGCVNCVRW-SENGKFLASGGDDKLIMIWQISRGFGSGKSFGSNVTILEHWRSVATLRG 613

Query: 129 HSKRVGIVAWHPTARNVLLSAGCDNAIIIWNVGTGEALINLDDMHSDMIYNVSWSRNGSL 188
           H+  V  +AW P     L S   DN I++WN       + +   H+ M+  V+W   G  
Sbjct: 612 HAGDVLDLAWSPQDL-WLASCSVDNTIVVWNALKFSEQVAVIRGHAGMVKGVTWDPVGRY 436

Query: 189 ICTASKDKKVRV 200
           + + S DK +RV
Sbjct: 435 LASQSDDKTLRV 400

 Score = 50.8 bits (120), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 32/88 (36%), Positives = 44/88 (50%)
 Frame = -1

Query: 71  KSYPTVCGHTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLTLSLTEPVVILEGHS 130
           +S  T+ GH G VLD+ W P  D  +AS S D T++VW        L  +E V ++ GH+
Sbjct: 636 RSVATLRGHAGDVLDLAWSPQ-DLWLASCSVDNTIVVWN------ALKFSEQVAVIRGHA 478

Query: 131 KRVGIVAWHPTARNVLLSAGCDNAIIIW 158
             V  V W P  R  L S   D  + +W
Sbjct: 477 GMVKGVTWDPVGR-YLASQSDDKTLRVW 397

 Score = 28.5 bits (62), Expect = 7.0,   Method: Compositional matrix adjust.
 Identities = 22/71 (30%), Positives = 34/71 (47%), Gaps = 1/71 (1%)
 Frame = -1

Query: 71  KSYPTVCGHTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPE-NGLTLSLTEPVVILEGH 129
           KS    CG T  VL ++W P  + V+++ + +      QI E NG   SL        GH
Sbjct: 363 KSCFKECGGTTHVLRLNWSPDGNHVVSAHAMNNAXPTAQIIERNGWGTSLD-----FVGH 199

Query: 130 SKRVGIVAWHP 140
            K + +V ++P
Sbjct: 198 RKAITVVRFNP 166
>19949
          Length = 903

 Score = 52.0 bits (123), Expect = 5e-07,   Method: Compositional matrix adjust.
 Identities = 40/177 (22%), Positives = 79/177 (44%)
 Frame = +2

Query: 83  VLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLTLSLTEPVVILEGHSKRVGIVAWHPTA 142
           V  +D+ P+     ASGS DC V +W I   G        +   +GH+  V  + + P  
Sbjct: 2   VKSLDFHPYG-AYTASGSMDCNVKLWDIRRKGC-------IYTYKGHTGCVCCLRFSPDG 157

Query: 143 RNVLLSAGCDNAIIIWNVGTGEALINLDDMHSDMIYNVSWSRNGSLICTASKDKKVRVID 202
           R  + SA  D  + +W++  G+ L +L  +H D +  + +  +  L+ + S D+ V+  D
Sbjct: 158 R-WIASASEDGLVKLWDLTAGKLLTDL-KLHRDAVNTIEFHPHEFLLASGSADRTVKFWD 331

Query: 203 PRKQEIVAEKEKAHEGARPMRAIFLADGNVFTTGFSRMSERQLALWNPKNMQEPIAL 259
               ++++  E      R +  +F  DG    +G       ++  W P  + + +++
Sbjct: 332 LETFQLISTTEPEANSIRSI--LFHPDGVCLYSG--SKDTLKVYHWEPLELYDTVSV 490
>12140
          Length = 727

 Score = 47.8 bits (112), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 37/110 (33%), Positives = 55/110 (50%), Gaps = 5/110 (4%)
 Frame = +2

Query: 96  IASGSEDCTVMVWQIPENGLTLSLTEPVVILEGHSKRVGIVAWHPTA---RNVLLSAGCD 152
             SG  D  V +W+  E G           LEGHS  V  VAW P+    RNV+ S   D
Sbjct: 269 FVSGGCDNLVKIWREDETGWVEDQK-----LEGHSDWVRDVAWAPSIGLPRNVIASCSQD 433

Query: 153 NAIIIW-NVGTGEALIN-LDDMHSDMIYNVSWSRNGSLICTASKDKKVRV 200
             +IIW N G+     + + +  SD++++VSWS  G+++  +  D KV +
Sbjct: 434 CRVIIWTNDGSSNQWTSRILNKFSDVVWHVSWSVTGNILAVSGGDNKVTL 583

 Score = 39.3 bits (90), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 30/84 (35%), Positives = 42/84 (50%), Gaps = 3/84 (3%)
 Frame = +2

Query: 78  GHTGPVLDIDWCPHND---QVIASGSEDCTVMVWQIPENGLTLSLTEPVVILEGHSKRVG 134
           GH+  V D+ W P       VIAS S+DC V++W    +G +   T    IL   S  V 
Sbjct: 350 GHSDWVRDVAWAPSIGLPRNVIASCSQDCRVIIW--TNDGSSNQWTSR--ILNKFSDVVW 517

Query: 135 IVAWHPTARNVLLSAGCDNAIIIW 158
            V+W  T  N+L  +G DN + +W
Sbjct: 518 HVSWSVTG-NILAVSGGDNKVTLW 586
>30108
          Length = 1032

 Score = 42.4 bits (98), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 38/123 (30%), Positives = 59/123 (47%), Gaps = 3/123 (2%)
 Frame = +1

Query: 83  VLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLTLSLTEPVVILEGHSKRVGI--VAWHP 140
           V  + W P +  V+A   +   V++W I    L    +   V +  HS    I  +AW P
Sbjct: 235 VAHLAWQPLSASVLAVACQS-AVLIWHIEPTSLAARPSSSSVQVLQHSGHCPITHLAWLP 411

Query: 141 TARNVLLSAG-CDNAIIIWNVGTGEALINLDDMHSDMIYNVSWSRNGSLICTASKDKKVR 199
           +A N+LLSA   D A++ W+VG GEA   L  +    +  ++ S +GS +  A+     R
Sbjct: 412 SA-NILLSASPVDTAVMAWSVG-GEACTALRYLGGGGVSLLACSPDGSKVMAATPATLFR 585

Query: 200 VID 202
           V D
Sbjct: 586 VWD 594
>02960
          Length = 1577

 Score = 42.4 bits (98), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 26/88 (29%), Positives = 50/88 (56%), Gaps = 2/88 (2%)
 Frame = +2

Query: 122  PVVILEGHSKRVGIVAWHPTARNVLLSAGCDNAIIIWNVGTGE--ALINLDDMHSDMIYN 179
            PV+ L GH++ V  V W    R  ++++  D+++ +W++ T +  +LI      S  + +
Sbjct: 935  PVLTLSGHAEAVSAVRWLDPHR--VVTSSWDHSLRLWDLHTAQQTSLIQ----GSKAVLD 1096

Query: 180  VSWSRNGSLICTASKDKKVRVIDPRKQE 207
            V++S    ++ T S D+ VR++DPR  E
Sbjct: 1097 VAYSPLSHMLITGSADRHVRLVDPRCSE 1180

 Score = 36.6 bits (83), Expect = 0.025,   Method: Compositional matrix adjust.
 Identities = 28/95 (29%), Positives = 44/95 (46%), Gaps = 5/95 (5%)
 Frame = +2

Query: 79   HTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLTLSLTEPVVILEGHSKRVGIVAW 138
            HTG V  +DW P  + +  SGS D  + +W       TL        +  H  R+  V W
Sbjct: 1211 HTGWVTGVDWSPTREHLFLSGSYDNVLKLWDTRSPKATL------YDMNWHEDRILAVDW 1372

Query: 139  HPTARNVLLSAGCDNAIIIWN-----VGTGEALIN 168
              +   +LLS G DN + +++     +GT + LI+
Sbjct: 1373 --SIPELLLSGGVDNKLHVFSYSSAKLGTTD*LID 1471

 Score = 35.8 bits (81), Expect = 0.037,   Method: Compositional matrix adjust.
 Identities = 22/73 (30%), Positives = 35/73 (47%)
 Frame = +2

Query: 129  HSKRVGIVAWHPTARNVLLSAGCDNAIIIWNVGTGEALINLDDMHSDMIYNVSWSRNGSL 188
            H+  V  V W PT  ++ LS   DN + +W+  + +A +   + H D I  V WS    L
Sbjct: 1211 HTGWVTGVDWSPTREHLFLSGSYDNVLKLWDTRSPKATLYDMNWHEDRILAVDWSIP-EL 1387

Query: 189  ICTASKDKKVRVI 201
            + +   D K+ V 
Sbjct: 1388 LLSGGVDNKLHVF 1426
>31474
          Length = 403

 Score = 42.0 bits (97), Expect = 6e-04,   Method: Composition-based stats.
 Identities = 27/89 (30%), Positives = 42/89 (47%), Gaps = 3/89 (3%)
 Frame = -3

Query: 115 LTLSLTEPVVILEGHSKRVGIVAWHPTARNVLLSAGCDNAIIIWNVGTGEALI---NLDD 171
           + ++  E V  L  H +    VAW+PT   +L S G D  I IW    G+  +    L D
Sbjct: 350 MAMATLEEVCCLSAHDEHAWCVAWNPTG-TLLASCGSDKIIKIWG-KEGDNWVCKSTLTD 177

Query: 172 MHSDMIYNVSWSRNGSLICTASKDKKVRV 200
            H+  + ++ WS  G+ + +AS D    V
Sbjct: 176 AHTRTVRSLGWSPCGNYLSSASFDATTAV 90

 Score = 31.6 bits (70), Expect = 0.81,   Method: Composition-based stats.
 Identities = 21/64 (32%), Positives = 26/64 (40%)
 Frame = -3

Query: 78  GHTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLTLSLTEPVVILEGHSKRVGIVA 137
            HT  V  + W P  +  ++S S D T  VW            E +  LEGH   V  VA
Sbjct: 176 AHTRTVRSLGWSPCGN-YLSSASFDATTAVWSRKGGEF-----ECIATLEGHENEVKAVA 15

Query: 138 WHPT 141
           W  T
Sbjct: 14  WART 3
>12841
          Length = 1364

 Score = 41.2 bits (95), Expect = 8e-04,   Method: Compositional matrix adjust.
 Identities = 27/113 (23%), Positives = 49/113 (43%), Gaps = 2/113 (1%)
 Frame = +1

Query: 75   TVCGHTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLTLSLTEPVVILEGHSKRVG 134
            T  GHT PV  I W P    +  S S D ++ +W           T P++     +K V 
Sbjct: 1033 TYSGHTAPVYHIRWSPFVSDIFLSCSADWSIRLWHQDR-------TTPILTFHSSTKTVH 1191

Query: 135  IVAWHPTARNVLLSAGCDNAIIIWNVG--TGEALINLDDMHSDMIYNVSWSRN 185
             V W P +  V      + A+ +W++   T +A+I +       + +V++ ++
Sbjct: 1192 DVCWSPRSSTVFACVH-EGAVEVWDLAQSTLDAVITITPTSGAKLTSVTFGKH 1347
>10264
          Length = 416

 Score = 40.4 bits (93), Expect = 0.001,   Method: Composition-based stats.
 Identities = 22/88 (25%), Positives = 40/88 (45%)
 Frame = -1

Query: 78  GHTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLTLSLTEPVVILEGHSKRVGIVA 137
           GH+  V D+ W PH+D  + S   D    VW + + G  L+        +GH  R+    
Sbjct: 251 GHSQRVTDMSWSPHHDARLVSVGYDAEAFVWDV-QKGTALAQ------FKGHMGRLLTCQ 93

Query: 138 WHPTARNVLLSAGCDNAIIIWNVGTGEA 165
           +     +++++ G D ++ +W V    A
Sbjct: 92  FSGLDPDLVMTGGSDASVHVWRVSQQAA 9

 Score = 37.7 bits (86), Expect = 0.011,   Method: Composition-based stats.
 Identities = 22/75 (29%), Positives = 32/75 (42%)
 Frame = -1

Query: 126 LEGHSKRVGIVAWHPTARNVLLSAGCDNAIIIWNVGTGEALINLDDMHSDMIYNVSWSRN 185
           L GHS+RV  ++W P     L+S G D    +W+V  G AL         ++       +
Sbjct: 257 LSGHSQRVTDMSWSPHHDARLVSVGYDAEAFVWDVQKGTALAQFKGHMGRLLTCQFSGLD 78

Query: 186 GSLICTASKDKKVRV 200
             L+ T   D  V V
Sbjct: 77  PDLVMTGGSDASVHV 33
>29912
          Length = 510

 Score = 40.4 bits (93), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 40/153 (26%), Positives = 61/153 (39%)
 Frame = +3

Query: 4   VVRQSKFRHVFGQAVKNDQCYDDIRVSRVTWDSSFCAVNPRFVAIIIEASGGGAFLVLPL 63
           V +Q K R + G A          RV  ++W+S   +   R        SG      +  
Sbjct: 96  VTQQKKLRTMAGHAA---------RVGSLSWNSFIVSSGSR--------SGN-----IHH 209

Query: 64  HKTGRIDKSYPTVCGHTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLTLSLTEPV 123
           H     D    T+ GH+  V  + W P + + +ASG+ D  + VW  P      + T+P+
Sbjct: 210 HDVRVADHHVGTLSGHSQEVCGLRWSP-DGKYLASGANDNLLCVW--PAQVTGGNSTQPL 380

Query: 124 VILEGHSKRVGIVAWHPTARNVLLSAGCDNAII 156
                H   V  +AW P   + L S G D  I+
Sbjct: 381 HTFSQHQAAVKALAWCPWQPSXLASGGGDVLIV 479
>00825
          Length = 1821

 Score = 40.0 bits (92), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 31/115 (26%), Positives = 51/115 (44%)
 Frame = -2

Query: 86   IDWCPHNDQVIASGSEDCTVMVWQIPENGLTLSLTEPVVILEGHSKRVGIVAWHPTARNV 145
            + W P     I S +ED  +  + + +      L+ P+ +   H+  V  V + PT R  
Sbjct: 1343 LSWNPMEAFTITSANEDGNLYTFDMRK------LSMPLNMHRDHTAAVMDVDYCPTGRE- 1185

Query: 146  LLSAGCDNAIIIWNVGTGEALINLDDMHSDMIYNVSWSRNGSLICTASKDKKVRV 200
             +SAG D  I I+ V  G +           + +V WSR+   I +AS +  +RV
Sbjct: 1184 FVSAGYDKVIRIFPVDKGHSREVYHTKRMQRVGSVVWSRDSKYIFSASDEMNIRV 1020

 Score = 33.1 bits (74), Expect = 0.28,   Method: Compositional matrix adjust.
 Identities = 23/91 (25%), Positives = 44/91 (48%)
 Frame = -2

Query: 79   HTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLTLSLTEPVVILEGHSKRVGIVAW 138
            HT  V+D+D+CP   + +++G  D  + ++ + + G +  +     +     +RVG V W
Sbjct: 1232 HTAAVMDVDYCPTGREFVSAGY-DKVIRIFPV-DKGHSREVYHTKRM-----QRVGSVVW 1074

Query: 139  HPTARNVLLSAGCDNAIIIWNVGTGEALINL 169
               ++  + SA  +  I +W     EAL  L
Sbjct: 1073 SRDSK-YIFSASDEMNIRVWKAVAWEALGKL 984
>01598
          Length = 1545

 Score = 40.0 bits (92), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 24/96 (25%), Positives = 44/96 (45%)
 Frame = +1

Query: 65   KTGRIDKSYPTVCGHTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLTLSLTEPVV 124
            +T  I  S   + GH+  V D+ W PH+D  + S   D    VW + + G  L+      
Sbjct: 1255 ETSLILTSLRELSGHSQRVTDMSWSPHHDARLVSVGYDAEAFVWDV-QKGTALAQ----- 1416

Query: 125  ILEGHSKRVGIVAWHPTARNVLLSAGCDNAIIIWNV 160
              +GH  R+    +     +++++ G D ++ +W V
Sbjct: 1417 -FKGHMGRLLTCQFSGLDPDLVMTGGSDASVHVWRV 1521

 Score = 37.0 bits (84), Expect = 0.016,   Method: Compositional matrix adjust.
 Identities = 23/81 (28%), Positives = 34/81 (41%)
 Frame = +1

Query: 126  LEGHSKRVGIVAWHPTARNVLLSAGCDNAIIIWNVGTGEALINLDDMHSDMIYNVSWSRN 185
            L GHS+RV  ++W P     L+S G D    +W+V  G AL         ++       +
Sbjct: 1288 LSGHSQRVTDMSWSPHHDARLVSVGYDAEAFVWDVQKGTALAQFKGHMGRLLTCQFSGLD 1467

Query: 186  GSLICTASKDKKVRVIDPRKQ 206
              L+ T   D  V V    +Q
Sbjct: 1468 PDLVMTGGSDASVHVWRVSQQ 1530

 Score = 28.9 bits (63), Expect = 4.9,   Method: Compositional matrix adjust.
 Identities = 27/111 (24%), Positives = 43/111 (38%)
 Frame = +1

Query: 72  SYPTVCGHTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLTLSLTEPVVILEGHSK 131
           S  T+ GH   V  +   P +   +A G  D  +  W +        +T    + +G   
Sbjct: 490 SMATLGGH---VYCVRTSPIDPGRVAVGVGDSMIRTWNMSNKTNPYDVT---TLWQGIKS 651

Query: 132 RVGIVAWHPTARNVLLSAGCDNAIIIWNVGTGEALINLDDMHSDMIYNVSW 182
           +V  VAWHPT    L     D  I +++V + +     +  H    Y V W
Sbjct: 652 KVTAVAWHPTKEGWLGFGTDDGRIGVFDVLSHKMPTLSNTFHHRTAYVVCW 804
>27475
          Length = 369

 Score = 38.9 bits (89), Expect = 0.004,   Method: Composition-based stats.
 Identities = 24/86 (27%), Positives = 40/86 (46%)
 Frame = +2

Query: 79  HTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLTLSLTEPVVILEGHSKRVGIVAW 138
           HTG V  +DW P  + +  SGS D  + +W       T S    +  +  H  R+  V W
Sbjct: 65  HTGWVTGVDWSPTREHLFLSGSYDNVLKLWD------TRSPKATLYDMNWHEDRILAVDW 226

Query: 139 HPTARNVLLSAGCDNAIIIWNVGTGE 164
             +   +LLS G DN + +++  + +
Sbjct: 227 --SIPELLLSGGVDNKLHVFSYSSAK 298

 Score = 37.7 bits (86), Expect = 0.011,   Method: Composition-based stats.
 Identities = 22/72 (30%), Positives = 35/72 (48%)
 Frame = +2

Query: 129 HSKRVGIVAWHPTARNVLLSAGCDNAIIIWNVGTGEALINLDDMHSDMIYNVSWSRNGSL 188
           H+  V  V W PT  ++ LS   DN + +W+  + +A +   + H D I  V WS    L
Sbjct: 65  HTGWVTGVDWSPTREHLFLSGSYDNVLKLWDTRSPKATLYDMNWHEDRILAVDWSIP-EL 241

Query: 189 ICTASKDKKVRV 200
           + +   D K+ V
Sbjct: 242 LLSGGVDNKLHV 277
>37180
          Length = 681

 Score = 38.1 bits (87), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 24/89 (26%), Positives = 44/89 (49%), Gaps = 1/89 (1%)
 Frame = +1

Query: 188 LICTASKDKKVRVIDPRKQEIVAEKEKAHEGARPMRAIFLADGNVFTTGFSRMSERQLAL 247
           L+ T+SKD   R+ D R   ++    + H   +P+ +   A G+   +G     +R + +
Sbjct: 61  LVVTSSKDMTFRLWDFRDSALLVNVFQGH--TQPVTSAVFASGDKVVSG---SDDRTVRV 225

Query: 248 WNPKNMQEPIALHEMDTSNGVLLPF-YDP 275
           W+ +NM+ PIA    D++    + F Y P
Sbjct: 226 WDMRNMRSPIATIRTDSAVNRFV*FQYRP 312

 Score = 36.6 bits (83), Expect = 0.026,   Method: Compositional matrix adjust.
 Identities = 23/81 (28%), Positives = 41/81 (50%)
 Frame = +1

Query: 125 ILEGHSKRVGIVAWHPTARNVLLSAGCDNAIIIWNVGTGEALINLDDMHSDMIYNVSWSR 184
           +L GH + +  V  HPT R V+ S+  D    +W+      L+N+   H+  + +  ++ 
Sbjct: 4   VLNGHDQELSDVHAHPTQRLVVTSSK-DMTFRLWDFRDSALLVNVFQGHTQPVTSAVFA- 177

Query: 185 NGSLICTASKDKKVRVIDPRK 205
           +G  + + S D+ VRV D R 
Sbjct: 178 SGDKVVSGSDDRTVRVWDMRN 240
>12574
          Length = 521

 Score = 38.1 bits (87), Expect = 0.009,   Method: Compositional matrix adjust.
 Identities = 23/75 (30%), Positives = 39/75 (52%)
 Frame = +3

Query: 126 LEGHSKRVGIVAWHPTARNVLLSAGCDNAIIIWNVGTGEALINLDDMHSDMIYNVSWSRN 185
           L GH+K +  V + P   + L S+  D  I IW    G+    +   H   + +V+WS +
Sbjct: 174 LAGHTKALSAVKFSPNG-DWLASSSADKLIKIWGAYDGKFEKTIAG-HKLGLSDVAWSSD 347

Query: 186 GSLICTASKDKKVRV 200
             L+C+AS DK +++
Sbjct: 348 SKLLCSASDDKTLKI 392
>37142
          Length = 327

 Score = 37.7 bits (86), Expect = 0.010,   Method: Compositional matrix adjust.
 Identities = 28/106 (26%), Positives = 51/106 (48%), Gaps = 5/106 (4%)
 Frame = +2

Query: 48  IIIEASGGGAFLVLPLHKT--GRIDKSYPTVCGHTGPVLDIDWCPHNDQVIASGSEDCTV 105
           +I+  +  G+ LV    K   G  D S   +  HTG V  +D+ P    ++ASG+ +  +
Sbjct: 2   VIVGGADNGSVLVYSAQKMIDGDADCSVLQLTKHTGAVKALDFNPFQTNLLASGASESEI 181

Query: 106 MVWQI--PENGLTLSL-TEPVVILEGHSKRVGIVAWHPTARNVLLS 148
            +W +  P+N +T    ++P        + V  VAW+   +++L S
Sbjct: 182 YIWDLNKPDNPMTPGQKSQP-------PEEVSCVAWNRQVQHILAS 298
>31384
          Length = 474

 Score = 37.7 bits (86), Expect = 0.010,   Method: Compositional matrix adjust.
 Identities = 19/58 (32%), Positives = 31/58 (53%), Gaps = 1/58 (1%)
 Frame = -1

Query: 146 LLSAGCDNAIIIWNVG-TGEALINLDDMHSDMIYNVSWSRNGSLICTASKDKKVRVID 202
           L+S   DN +  W V  +G+ +      H+  + +V WS +G+ + TAS DK  +V D
Sbjct: 222 LISGSWDNKVSCWEVQQSGQTIPKAQQTHTGPVLDVDWSDDGTKVFTASCDKTAKVWD 49

 Score = 31.6 bits (70), Expect = 0.77,   Method: Compositional matrix adjust.
 Identities = 16/35 (45%), Positives = 20/35 (57%)
 Frame = -1

Query: 79  HTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPEN 113
           HTGPVLD+DW     +V  + S D T  VW +  N
Sbjct: 138 HTGPVLDVDWSDDGTKVF-TASCDKTAKVWDLNSN 37

 Score = 28.9 bits (63), Expect = 4.5,   Method: Compositional matrix adjust.
 Identities = 17/71 (23%), Positives = 33/71 (46%)
 Frame = -1

Query: 96  IASGSEDCTVMVWQIPENGLTLSLTEPVVILEGHSKRVGIVAWHPTARNVLLSAGCDNAI 155
           + SGS D  V  W++ ++G T+   +     + H+  V  V W      V  +A CD   
Sbjct: 222 LISGSWDNKVSCWEVQQSGQTIPKAQ-----QTHTGPVLDVDWSDDGTKV-FTASCDKTA 61

Query: 156 IIWNVGTGEAL 166
            +W++ + + +
Sbjct: 60  KVWDLNSNQCM 28
>21921
          Length = 1341

 Score = 37.7 bits (86), Expect = 0.011,   Method: Compositional matrix adjust.
 Identities = 26/91 (28%), Positives = 42/91 (46%), Gaps = 1/91 (1%)
 Frame = -1

Query: 78  GHTGPVLDIDWCPH-NDQVIASGSEDCTVMVWQIPENGLTLSLTEPVVILEGHSKRVGIV 136
           GHTG V  I  CP    Q + SGS+D T+  W++       +L             V  V
Sbjct: 489 GHTGIVRSI--CPDPTGQWLVSGSDDGTIRFWEVSSGRCMKTLQV--------GGCVTSV 340

Query: 137 AWHPTARNVLLSAGCDNAIIIWNVGTGEALI 167
           AW+P     +++A  +  +++ N G G+ L+
Sbjct: 339 AWNPNPSLCVVAATLNTTVLLINPGLGDKLV 247
>27465
          Length = 658

 Score = 37.4 bits (85), Expect = 0.012,   Method: Compositional matrix adjust.
 Identities = 31/130 (23%), Positives = 55/130 (42%)
 Frame = -1

Query: 78  GHTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLTLSLTEPVVILEGHSKRVGIVA 137
            H  P+ ++ +       I +GS D T  +W            E +  LEGH   V  +A
Sbjct: 367 AHILPLTNVAFNKSGSSFI-TGSYDRTCKIWDTAS-------AEELHTLEGHRNVVYAIA 212

Query: 138 WHPTARNVLLSAGCDNAIIIWNVGTGEALINLDDMHSDMIYNVSWSRNGSLICTASKDKK 197
           ++    + +++   D    +W+   G+    L   H+  I  VS++ + +LI T S D  
Sbjct: 211 FNNPFGDKVITGSFDKTCKLWSTADGKCYHTLRG-HTAEIVCVSFNPSSTLIATGSMDTT 35

Query: 198 VRVIDPRKQE 207
            R+ D  K +
Sbjct: 34  CRLWDVEKAQ 5
>04358
          Length = 2430

 Score = 36.6 bits (83), Expect = 0.022,   Method: Compositional matrix adjust.
 Identities = 43/211 (20%), Positives = 87/211 (41%), Gaps = 6/211 (2%)
 Frame = +1

Query: 115  LTLSLTEPVVILEGHSKRVGIVAWHPTARNVLLSAGCDNAIIIWNVGTGEALINLDDMHS 174
            ++L  TEP  +L       G+ A H    + L++A   N ++        A  N    H 
Sbjct: 1264 VSLYKTEPHYVL-------GLAAQHTGGADSLVAAASSNFMVRLYSRCRLAQTNTLTGHD 1422

Query: 175  DMIYNVSW-SRNGSLICTASKDKKVRVIDPRKQEIVAEKEKAHEGARPMRAIFLA-DGN- 231
            D+I ++ +   +  LI TAS D  VR+ DPR    V+++ +   G +  +   L+ D N 
Sbjct: 1423 DVISSIRFLHTDPGLIMTASHDHTVRIWDPRAS--VSKEVQRFSGEQNTKCSVLSCDVNI 1596

Query: 232  ---VFTTGFSRMSERQLALWNPKNMQEPIALHEMDTSNGVLLPFYDPDTSIIYLCGKGDS 288
               V   G    ++    L+  +   + +  +E    + +    + P +    L G  D 
Sbjct: 1597 SDRVLCAGTEMSNDDAYLLFWDRRKDKLLGCYEDSHHDDITQVHFGPTSEKTLLTGSTDG 1776

Query: 289  SIRYFEITDESPYVHYLNTFSSKEPQRGMGY 319
             +  F++   +     ++T++++      G+
Sbjct: 1777 LVNVFDVMQTTEDDALMSTYNTEATVERAGW 1869
>06576
          Length = 1547

 Score = 36.6 bits (83), Expect = 0.023,   Method: Compositional matrix adjust.
 Identities = 42/178 (23%), Positives = 74/178 (41%), Gaps = 1/178 (0%)
 Frame = -2

Query: 78   GHTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLTLSLTEPVVILEGHSKRVGIVA 137
            GHT  V  + + P  +  + S  +D T  VW   ++G      E V+           V 
Sbjct: 1090 GHTDFVNSVTFSPTEEDQVXSTGDDLTCRVW-TGKDGQDGRYGESVIFRLTAPGMA--VC 920

Query: 138  WHPTARNVLLSAGCDNAIIIWNVGTGEALINLDDMHSDMIYNVSWSRNGSLICTASKDKK 197
            WH      L+    D  I  +++   + +++L    S ++ +  WS++  L+  A     
Sbjct: 919  WHADEPLKLMVGQKDGIIRFFSLSNQQPIMSLSCGVSPLL-DCDWSKHNCLLVGAVAGAD 743

Query: 198  VRVIDPRKQEIVAEKEKAH-EGARPMRAIFLADGNVFTTGFSRMSERQLALWNPKNMQ 254
              V D     +  +K +AH EGAR  R     +  V T G     +RQ+ ++N ++ Q
Sbjct: 742  WIVFDTSVSSMPLDKRQAHVEGARNFRWSRCHESLVATLG---RPQRQVKVFNTRHQQ 578
>28289
          Length = 349

 Score = 35.8 bits (81), Expect = 0.036,   Method: Composition-based stats.
 Identities = 24/78 (30%), Positives = 40/78 (51%), Gaps = 3/78 (3%)
 Frame = -1

Query: 126 LEGHSKRVGIVAWHPTARNVLLSAGCDNAIIIWNVGTG---EALINLDDMHSDMIYNVSW 182
           LEGHS  V +VAW+   +  L ++     II+W +  G   E +IN  + +  ++  + W
Sbjct: 244 LEGHSGAVQVVAWNEHHQK-LTTSDQYGLIIVWMLYKGSWYEEMIN--NRNKSVVRGMKW 74

Query: 183 SRNGSLICTASKDKKVRV 200
           + +G  IC   +D  V V
Sbjct: 73  TADGQKICIVYEDGAVIV 20
>30256
          Length = 961

 Score = 35.8 bits (81), Expect = 0.036,   Method: Compositional matrix adjust.
 Identities = 32/114 (28%), Positives = 55/114 (48%)
 Frame = +3

Query: 96  IASGSEDCTVMVWQIPENGLTLSLTEPVVILEGHSKRVGIVAWHPTARNVLLSAGCDNAI 155
           + SGS D T+ VW I E+G  L+      +L GH   V  V +       ++S   D  +
Sbjct: 201 VVSGSRDATLRVWDI-ESGHCLN------VLLGHMAAVRCVQYDGKR---VVSGAXDYTV 350

Query: 156 IIWNVGTGEALINLDDMHSDMIYNVSWSRNGSLICTASKDKKVRVIDPRKQEIV 209
            +W+  T   L  L   H++ +Y++ +  +G  + + S D  +RV D R  ++V
Sbjct: 351 RVWDPDTASCLHTLQG-HTNRVYSLQF--DGVYVVSGSLDTSIRVWDVRCGKLV 503

 Score = 28.9 bits (63), Expect = 4.9,   Method: Compositional matrix adjust.
 Identities = 26/118 (22%), Positives = 52/118 (44%), Gaps = 8/118 (6%)
 Frame = +3

Query: 93  DQVIASGSEDCTVMVWQIPENGLTLSLTEPVVILEGHSKRVGIVAWHPTARNVLLSAGCD 152
           D ++ SG+ D TV VW +       +L  P      H   V  + ++   +  +++   D
Sbjct: 552 DNLLVSGNADSTVKVWDVHTGKCLQTLLGP----NKHRSAVTCLQFN---KKFVVTCSDD 710

Query: 153 NAIIIWNVGTGEALINLDDMHSDMIYNVSW---SRNGSLICT-----ASKDKKVRVID 202
             + +W++ TG+ + NL  + S     V W     N  ++C       +++ K+ V+D
Sbjct: 711 GTVKLWDLNTGDFIRNLITLPSGGSGGVVWRLRCNNTKMVCAVGSRNGTEETKLLVLD 884
>14516
          Length = 581

 Score = 35.0 bits (79), Expect = 0.061,   Method: Compositional matrix adjust.
 Identities = 34/103 (33%), Positives = 43/103 (41%)
 Frame = -3

Query: 56  GAFLVLPLHKTGRIDKSYPTVCGHTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPENGL 115
           G F VL  +  G  DK        TG +       H +  I + S D TV   Q+ E GL
Sbjct: 456 GKFEVLQSYDVGHKDKL-------TGVI-------HTEGAIYTSSNDKTV---QVLEPGL 328

Query: 116 TLSLTEPVVILEGHSKRVGIVAWHPTARNVLLSAGCDNAIIIW 158
                 P+  LE H   V  +A+      VL SAGCD  + IW
Sbjct: 327 N---PRPITTLEKHQSGVAGIAYQ---NGVLASAGCDITVGIW 217
>17602
          Length = 481

 Score = 35.0 bits (79), Expect = 0.068,   Method: Compositional matrix adjust.
 Identities = 20/46 (43%), Positives = 29/46 (63%)
 Frame = +3

Query: 157 IWNVGTGEALINLDDMHSDMIYNVSWSRNGSLICTASKDKKVRVID 202
           IW+V TG+ L  L   HSD +  V ++R+GSLI ++S D   R+ D
Sbjct: 6   IWDVKTGKCLKTLP-AHSDPVTAVHFNRDGSLIVSSSYDGLCRIWD 140
>13335
          Length = 863

 Score = 34.7 bits (78), Expect = 0.096,   Method: Compositional matrix adjust.
 Identities = 50/209 (23%), Positives = 80/209 (38%), Gaps = 56/209 (26%)
 Frame = +1

Query: 96  IASGSEDCTVMVWQIPENGLTLSLT---EPVVIL----EGHSKRVG-----IVAW----- 138
           + SGS+D T+ +W++    L  S     + V+ L     GH    G     +  W     
Sbjct: 106 LVSGSDDDTICMWEVATQKLVRSYVGHEDSVMALAYSPNGHYLVSGSPNGDLYVWDASFG 285

Query: 139 ---HPTAR----------------------------NVLLSAGC-DNAIIIWN----VGT 162
              H T R                            N+LL+ G  DN I +W     VG+
Sbjct: 286 HCRHLTLRVDAHDLGVTCCEFSPTFGTACAENSSTCNLLLATGGKDNLIKLWTFSAQVGS 465

Query: 163 GEALINLDDM---HSDMIYNVSWSRNGSLICTASKDKKVRVIDPRKQEIVAEKEKAHEGA 219
            E  +   D+   HSD++   ++S + +L+ + S DK VR+ D  K   +   E  H   
Sbjct: 466 PEVTLQCRDILSGHSDLVMACAFSPSSALLASGSFDKSVRLWDSVKGVALFSIEACHSRF 645

Query: 220 RPMRAIFLADGNVFTTGFSRMSERQLALW 248
               A F  DG +  +G     +R + +W
Sbjct: 646 VTCCA-FSIDGTLLASG---SMDRIIKIW 720
>03156
          Length = 1014

 Score = 34.3 bits (77), Expect = 0.12,   Method: Compositional matrix adjust.
 Identities = 42/160 (26%), Positives = 71/160 (44%), Gaps = 4/160 (2%)
 Frame = +1

Query: 83  VLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLTLSLTEPVVILEGHSKRVGIVAWHPTA 142
           V D+ W P +  +I +G ED  V ++     G+  S T+   I +          +  T 
Sbjct: 316 VTDVKWLPGSHLIIQAG-EDKEVRIYDSRTLGIVRSFTKKQYI-QMSCDVTADGQFCLTC 489

Query: 143 RNVLLSAGCDNAIIIWNVGTGEALINLDDMHSDMIYNVSW---SRNGSLICTASKDKKVR 199
            N     GC+    +W +  G ++ N    H + I    +   +++ +LI TAS+D  VR
Sbjct: 490 SNGFGGNGCE--ATLWQLSDG-SIQNEFKGHREAIEACLFLPSNQDMTLIATASRDCSVR 660

Query: 200 VIDPRKQEIVAEKEKAHEGARPMRA-IFLADGNVFTTGFS 238
           V +   +E V E+    EG  P+ + I   DG+V    F+
Sbjct: 661 VWNMFTKECVCEQN--FEGTGPLTSMIAYGDGSVLVGTFN 774
>02147
          Length = 1547

 Score = 34.3 bits (77), Expect = 0.12,   Method: Compositional matrix adjust.
 Identities = 21/58 (36%), Positives = 35/58 (60%), Gaps = 1/58 (1%)
 Frame = +2

Query: 53  SGGGAFLVLPL-HKTGRIDKSYPTVCGHTGPVLDIDWCPHNDQVIASGSEDCTVMVWQ 109
           +GG  F +    ++TG+  +S+    GH GPV  + + P + ++ ASGSED T+ +WQ
Sbjct: 719 AGGEDFKMYKFDYETGKEIESFK---GHFGPVHCVRFSP-DGELYASGSEDGTLRLWQ 880
>01327
          Length = 2215

 Score = 34.3 bits (77), Expect = 0.12,   Method: Compositional matrix adjust.
 Identities = 42/160 (26%), Positives = 71/160 (44%), Gaps = 4/160 (2%)
 Frame = +3

Query: 83  VLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLTLSLTEPVVILEGHSKRVGIVAWHPTA 142
           V D+ W P +  +I +G ED  V ++     G+  S T+   I +          +  T 
Sbjct: 426 VTDVKWLPGSHLIIQAG-EDKEVRIYDSRTLGIVRSFTKKQYI-QMSCDVTADGQFCLTC 599

Query: 143 RNVLLSAGCDNAIIIWNVGTGEALINLDDMHSDMIYNVSW---SRNGSLICTASKDKKVR 199
            N     GC+    +W +  G ++ N    H + I    +   +++ +LI TAS+D  VR
Sbjct: 600 SNGFGGNGCE--ATLWQLSDG-SIQNEFKGHREAIEACLFLPSNQDMTLIATASRDCSVR 770

Query: 200 VIDPRKQEIVAEKEKAHEGARPMRA-IFLADGNVFTTGFS 238
           V +   +E V E+    EG  P+ + I   DG+V    F+
Sbjct: 771 VWNMFTKECVCEQN--FEGTGPLTSMIAYGDGSVLVGTFN 884
>18981
          Length = 407

 Score = 34.3 bits (77), Expect = 0.12,   Method: Composition-based stats.
 Identities = 25/103 (24%), Positives = 44/103 (42%), Gaps = 9/103 (8%)
 Frame = -2

Query: 91  HNDQV---------IASGSEDCTVMVWQIPENGLTLSLTEPVVILEGHSKRVGIVAWHPT 141
           HND V         + SGS D T++VW++           PV  L GH++ +  V +   
Sbjct: 301 HNDDVECVCIYGRRVVSGSWDKTLIVWEVDTG-------RPVHQLHGHTEAITAVQFD-- 149

Query: 142 ARNVLLSAGCDNAIIIWNVGTGEALINLDDMHSDMIYNVSWSR 184
                +S   D  +  W + TG+ L+ +       +Y V +++
Sbjct: 148 -EGKAVSGSADGDVRTWALDTGQCLLTMTTGQDIEVYCVVYNQ 23
>15745
          Length = 1183

 Score = 33.5 bits (75), Expect = 0.20,   Method: Compositional matrix adjust.
 Identities = 32/138 (23%), Positives = 59/138 (42%), Gaps = 14/138 (10%)
 Frame = +2

Query: 136 VAWHPTARNVLLSAGCDNAIIIW--NVGTGEA----LINLDDMHSDMIYNVSWS--RNGS 187
           + WHPT  +  +   C++ +I+W  NV +  A    +I L+      +    W+   N +
Sbjct: 446 ILWHPTGDSQTVLGVCEDRVIMWDLNVASSSAQQTDMITLEGKGQPRLTCGRWNPHHNCA 625

Query: 188 LICTASKDKKVRVIDPRKQEIVAEKEKAHEGA------RPMRAIFLADGNVFTTGFSRMS 241
            I TA+ +  +R  D R ++   + E AH          P R  +LA         S   
Sbjct: 626 QIATAN-EATIRGWDLRSKQQTYQMEGAHGQLVRDLDFNPNRQYYLA---------SCGD 775

Query: 242 ERQLALWNPKNMQEPIAL 259
           + ++  W+ +N  EP+ +
Sbjct: 776 DCRVKFWDTRNCSEPLKV 829

 Score = 32.0 bits (71), Expect = 0.51,   Method: Compositional matrix adjust.
 Identities = 19/63 (30%), Positives = 30/63 (47%)
 Frame = +2

Query: 71  KSYPTVCGHTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLTLSLTEPVVILEGHS 130
           ++Y     H   V D+D+ P+    +AS  +DC V  W       T + +EP+ +L  HS
Sbjct: 683 QTYQMEGAHGQLVRDLDFNPNRQYYLASCGDDCRVKFWD------TRNCSEPLKVLSDHS 844

Query: 131 KRV 133
             V
Sbjct: 845 HWV 853
>04088
          Length = 511

 Score = 32.3 bits (72), Expect = 0.38,   Method: Compositional matrix adjust.
 Identities = 25/86 (29%), Positives = 34/86 (39%), Gaps = 5/86 (5%)
 Frame = +3

Query: 78  GHTGPVLDIDWCPHN-DQVIASGSEDCTVMVWQIPENGLTLSL----TEPVVILEGHSKR 132
           GH      ID C +N D ++ SGSED  V  W + E  L  +L    T PV  L  H   
Sbjct: 150 GHKHSQYKIDSCLNNEDTLVVSGSEDGKVYFWDLVEAKLVDTLDHKTTRPVHSLSFHHAE 329

Query: 133 VGIVAWHPTARNVLLSAGCDNAIIIW 158
                       + L   C + + +W
Sbjct: 330 ------------LCLMTACADKVFLW 371
>05642
          Length = 445

 Score = 32.3 bits (72), Expect = 0.44,   Method: Composition-based stats.
 Identities = 25/86 (29%), Positives = 34/86 (39%), Gaps = 5/86 (5%)
 Frame = -1

Query: 78  GHTGPVLDIDWCPHN-DQVIASGSEDCTVMVWQIPENGLTLSL----TEPVVILEGHSKR 132
           GH      ID C +N D ++ SGSED  V  W + E  L  +L    T PV  L  H   
Sbjct: 421 GHKHSQYKIDSCLNNEDTLVVSGSEDGKVYFWDLVEAKLVDTLDHKTTRPVHSLSFHHAE 242

Query: 133 VGIVAWHPTARNVLLSAGCDNAIIIW 158
                       + L   C + + +W
Sbjct: 241 ------------LCLMTACADKVFLW 200
>31864
          Length = 545

 Score = 32.3 bits (72), Expect = 0.45,   Method: Compositional matrix adjust.
 Identities = 13/45 (28%), Positives = 27/45 (60%)
 Frame = +2

Query: 158 WNVGTGEALINLDDMHSDMIYNVSWSRNGSLICTASKDKKVRVID 202
           W+V  G+ +++    H+  I ++  S++G++  TASKD   ++ D
Sbjct: 2   WDVRKGQKVVDSGVDHTGGINDMQLSKDGTMFVTASKDTTAKLFD 136
>03395
          Length = 2795

 Score = 32.0 bits (71), Expect = 0.57,   Method: Compositional matrix adjust.
 Identities = 28/117 (23%), Positives = 50/117 (42%)
 Frame = +2

Query: 92  NDQVIASGSEDCTVMVWQIPENGLTLSLTEPVVILEGHSKRVGIVAWHPTARNVLLSAGC 151
           ND+   S S D + ++W +  N      T   ++L   +     V +     ++L S G 
Sbjct: 179 NDRCCVSASTDGSTIIWDLITN------TRSQIVLA--NTLFKCVCFGGKDLHILTS-GT 331

Query: 152 DNAIIIWNVGTGEALINLDDMHSDMIYNVSWSRNGSLICTASKDKKVRVIDPRKQEI 208
           D+ I  W VG G  L  L+   +  I  +   R+G  I T  +D  +++    + E+
Sbjct: 332 DHKIGYWEVGDGGLLRELEGSQTGAINTIDIDRDGQTILTGGEDSLLKLWRYNEGEV 502
>19863
          Length = 502

 Score = 30.4 bits (67), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 22/65 (33%), Positives = 35/65 (53%)
 Frame = +1

Query: 96  IASGSEDCTVMVWQIPENGLTLSLTEPVVILEGHSKRVGIVAWHPTARNVLLSAGCDNAI 155
           + SGS D +++VW + ENG+        + L+GH+  V  V +    +  LLS   DN +
Sbjct: 16  LVSGSSDMSIVVWDV-ENGV------QKLRLQGHAGWVNDVHF-SQDQCWLLSCSNDNTV 171

Query: 156 IIWNV 160
            IWN+
Sbjct: 172 RIWNI 186
>14500
          Length = 1238

 Score = 30.0 bits (66), Expect = 1.9,   Method: Compositional matrix adjust.
 Identities = 33/139 (23%), Positives = 60/139 (43%), Gaps = 11/139 (7%)
 Frame = +3

Query: 88  WCPHNDQVIAS--GSEDCTVMVWQIPENGLTLSLTEPVVILEGHSKRVGIVAWHPTARNV 145
           WCP    ++AS  G+ D  +  W     G  LS  +          +V  + W    R +
Sbjct: 225 WCPWQPSLLASGGGTADRHIHFWNC-NTGTNLSSVDT-------KSQVCALLWSKEHREL 380

Query: 146 LLSAG-CDNAIIIWNVGTGEALINLDDMHSDMIYNVSWSRNGSLICTASKDKKVRV---- 200
           + S G   N +IIW       +  L   H+  + +++ S +G  + +A+ D+ +R+    
Sbjct: 381 ISSHGFAQNQLIIWKYPAMSRVAELTG-HTARVLHMAMSPDGETVVSAAADETLRLWKCF 557

Query: 201 -IDPRK---QEIVAEKEKA 215
            +D  K   ++ V EK +A
Sbjct: 558 TVDKEKKRPKQKVQEKNQA 614
>15118
          Length = 1074

 Score = 28.9 bits (63), Expect = 4.4,   Method: Compositional matrix adjust.
 Identities = 32/135 (23%), Positives = 61/135 (45%)
 Frame = +3

Query: 65  KTGRIDKSYPTVCGHTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLTLSLTEPVV 124
           ++G+   S+     H   V  + +   N  +I +G  DC +  W+         L + + 
Sbjct: 147 QSGKHRGSFGDTVAHVSGVRGVAFDAFNCLLITAGG-DCDIKFWRFGSRDRARVLLKELK 323

Query: 125 ILEGHSKRVGIVAWHPTARNVLLSAGCDNAIIIWNVGTGEALINLDDMHSDMIYNVSWSR 184
           + EG S+    +  H  + N+L     D  + + +V T   ++ +   HS+ I ++S+S 
Sbjct: 324 MSEGISR----ILLHRDS-NMLAVVLEDFTVSVIDVDTLR-VVRVFSGHSNSITDLSFSG 485

Query: 185 NGSLICTASKDKKVR 199
           +G  + TAS D  VR
Sbjct: 486 DGRWLITASMDCTVR 530
>27681
          Length = 465

 Score = 28.9 bits (63), Expect = 4.7,   Method: Composition-based stats.
 Identities = 13/29 (44%), Positives = 17/29 (58%), Gaps = 1/29 (3%)
 Frame = +2

Query: 64  HKTGR-IDKSYPTVCGHTGPVLDIDWCPH 91
           H  GR + + Y TV  H+ P LD+DW  H
Sbjct: 359 HYMGRQLRELYTTVRFHSAPALDVDWQTH 445
>26107
          Length = 1338

 Score = 28.9 bits (63), Expect = 5.0,   Method: Compositional matrix adjust.
 Identities = 13/45 (28%), Positives = 22/45 (48%)
 Frame = -3

Query: 158  WNVGTGEALINLDDMHSDMIYNVSWSRNGSLICTASKDKKVRVID 202
            W  G     ++    H++ +++ SW  N S   TAS D+ V + D
Sbjct: 1135 WRYGQDSPTVHRWXAHNNAVFDYSWISNDSQCLTASGDQTVALWD 1001
>25880
          Length = 423

 Score = 28.5 bits (62), Expect = 6.9,   Method: Composition-based stats.
 Identities = 20/78 (25%), Positives = 36/78 (46%), Gaps = 2/78 (2%)
 Frame = +2

Query: 157 IWNVGTGEALINLDDMHSDMIYNVSWSRNGSLICTASKDKKVRVIDPRKQEIVAEKEKAH 216
           +WN  +G  + +    H  ++ +V++  +   I T S +K VRV +  + +   E    H
Sbjct: 11  VWNAVSGAEIHSFQ--HKHIVKSVAFDNSSENIVTGSNEKLVRVFNLEQPDAEPELYGGH 184

Query: 217 EGA--RPMRAIFLADGNV 232
            GA  R + A    DG +
Sbjct: 185 TGAIKRALYASGSEDGTL 238
>05303
          Length = 782

 Score = 28.1 bits (61), Expect = 7.1,   Method: Compositional matrix adjust.
 Identities = 18/66 (27%), Positives = 31/66 (46%), Gaps = 11/66 (16%)
 Frame = -3

Query: 146 LLSAGCDNAIIIWNVGTGEALINLDDMHS-----------DMIYNVSWSRNGSLICTASK 194
            +  G DN++ +WNV   +AL+ +   HS           + I  V+  +   L+ T SK
Sbjct: 657 FIMGGQDNSVSLWNVNKKKALVCVTSAHSGCSQIEGSKGENWITAVASLQFTDLVATGSK 478

Query: 195 DKKVRV 200
           D  +R+
Sbjct: 477 DGCIRL 460
>38362
          Length = 1255

 Score = 28.1 bits (61), Expect = 7.2,   Method: Compositional matrix adjust.
 Identities = 10/34 (29%), Positives = 20/34 (58%)
 Frame = -1

Query: 167 INLDDMHSDMIYNVSWSRNGSLICTASKDKKVRV 200
           + L D H   ++ VSW+  G+++ ++  D  VR+
Sbjct: 637 VGLFDSHDSQVWRVSWNVTGTILVSSGADGCVRI 536
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31543950|ref|NP_084205.2| vacuolar sorting protein
33a [Mus musculus]
         (598 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

12886                                                                 337   1e-92
13186                                                                  72   5e-13
30185                                                                  31   1.2  
>12886
          Length = 2104

 Score =  337 bits (863), Expect = 1e-92,   Method: Compositional matrix adjust.
 Identities = 160/267 (59%), Positives = 211/267 (79%), Gaps = 8/267 (2%)
 Frame = +1

Query: 335 EIKQFASQLPHMQAARGSLANHTSIAELIKDVTTSEDFFDKLTVEQEFMSGIDTDKVNSY 394
           E+KQF S+LPH+QA+R SLA HTSIAEL+K+ T ++DF D L  +QEF++G++TDKV+  
Sbjct: 1   EMKQFVSKLPHLQASRQSLATHTSIAELVKEFTDTDDFIDALRCQQEFINGLETDKVHPL 180

Query: 395 IEDCIAQKHPLIKVLRLVCLQSVCNSGLKQKVLDYYRREILQTYGYEHILTLNNLEKAGL 454
           IE+ IA+   L KVLRL+C+QS+CN GLK KVLD+YR EILQ YG+EH+LTL+ LE+ GL
Sbjct: 181 IEEYIAKSESLSKVLRLICIQSICNDGLKPKVLDFYRHEILQVYGFEHMLTLHYLEQVGL 360

Query: 455 LKAQTGGRNNYPTIRKTLRLWMDDVNEQNPTDISYVYSGYAPLSVRLAQLLSRPGWRSIE 514
           L+    G  +Y  +RK+L+L +++VNEQNP+DI+YVYSGYAPLSVRLAQ L+RPGWRSI 
Sbjct: 361 LRPH--GARSYQVLRKSLKLIVEEVNEQNPSDIAYVYSGYAPLSVRLAQYLARPGWRSIT 534

Query: 515 EVLRILPGPHFEERQPLPTGLQKKR--------QPGENRVTLVFFLGGVTFAEIAALRFL 566
           EVL +LPGP  EE Q +P  L+K+R          GE ++TLV+FLGGVTFAEIAALRFL
Sbjct: 535 EVLNLLPGPRVEEVQQIPPALRKRRASITSTQSSSGEQKLTLVYFLGGVTFAEIAALRFL 714

Query: 567 SQLEDGGTEYVIATTKLMNGNSWIEAL 593
           +Q +DGGT+YV+AT+ LM+G+  ++ L
Sbjct: 715 AQQDDGGTDYVVATSNLMSGHRLLDCL 795
>13186
          Length = 777

 Score = 72.4 bits (176), Expect = 5e-13,   Method: Compositional matrix adjust.
 Identities = 34/61 (55%), Positives = 47/61 (77%), Gaps = 5/61 (8%)
 Frame = -2

Query: 538 KRQPGENRVTLVFFLGGVTFAEIAALRFLSQLED-----GGTEYVIATTKLMNGNSWIEA 592
           +   GE ++TLV+FLGGVTFAEIAALRFL+Q +D     GGT+YV+AT+ LM+G+  ++ 
Sbjct: 752 QSSSGEQKLTLVYFLGGVTFAEIAALRFLAQQDDEDCFSGGTDYVVATSNLMSGHRLLDC 573

Query: 593 L 593
           L
Sbjct: 572 L 570
>30185
          Length = 397

 Score = 31.2 bits (69), Expect = 1.2,   Method: Composition-based stats.
 Identities = 18/30 (60%), Positives = 19/30 (63%), Gaps = 3/30 (10%)
 Frame = -3

Query: 398 CIA-QKHP--LIKVLRLVCLQSVCNSGLKQ 424
           CI  QKH   LIKV  LVCL+S CN  LK 
Sbjct: 158 CICXQKHTECLIKVCILVCLRSTCNVSLKH 69
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31980808|ref|NP_058572.2| eukaryotic translation
initiation factor 3, subunit G [Mus musculus]
         (320 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

01278                                                                 335   1e-92
29459                                                                  80   8e-16
00302                                                                  53   2e-07
17681                                                                  51   6e-07
25691                                                                  47   1e-05
03744                                                                  46   2e-05
02502                                                                  46   2e-05
20488                                                                  46   2e-05
30672                                                                  45   4e-05
14637                                                                  45   6e-05
11687                                                                  44   8e-05
23322                                                                  44   9e-05
14258                                                                  44   9e-05
12350                                                                  44   1e-04
31618                                                                  44   1e-04
03000                                                                  43   1e-04
12506                                                                  42   2e-04
31310                                                                  42   4e-04
13457                                                                  42   5e-04
33516                                                                  42   5e-04
00556                                                                  41   8e-04
23250                                                                  40   0.001
15371                                                                  40   0.001
02343                                                                  40   0.001
11019                                                                  39   0.002
03059                                                                  39   0.003
11126                                                                  39   0.004
01937                                                                  38   0.007
16427                                                                  37   0.009
11108                                                                  37   0.013
00781                                                                  35   0.038
01065                                                                  35   0.046
39789                                                                  35   0.059
00738                                                                  34   0.077
19733                                                                  33   0.11 
15503                                                                  33   0.18 
00029                                                                  32   0.37 
16016                                                                  32   0.45 
15994                                                                  31   0.68 
31364                                                                  29   2.2  
36030                                                                  29   2.5  
18706                                                                  29   2.8  
12037                                                                  28   4.1  
16077                                                                  28   4.3  
21440                                                                  28   5.7  
31265                                                                  27   7.5  
17775                                                                  27   8.8  
>01278
          Length = 1082

 Score =  335 bits (860), Expect = 1e-92,   Method: Compositional matrix adjust.
 Identities = 166/262 (63%), Positives = 204/262 (77%), Gaps = 7/262 (2%)
 Frame = +2

Query: 64  IKTVTEYKIEEDGKKFKIVRTFRIETRKASKAVARRKNWKKFGNSEFDPPGPNVATTTVS 123
           +K +TE+K  E+GK  K V+T++ +T K SK++A+RK WKKFG +E DPPGPN A T +S
Sbjct: 119 LKKITEFKYNEEGKIVKTVKTYQTKTLKVSKSIAQRKTWKKFGAAEMDPPGPNPANTVIS 298

Query: 124 DDVSMTFITSKEDLNCQEEEDPMNKLKGQKIVSCRICKGDHWTTRCPYKDTLGPMQKELA 183
           +++ M F+ S E    +EE+DP+ KLK QKIV+CRICKGDHWTT+CPYKDTL P+Q++L 
Sbjct: 299 EEIFMQFVNSSEQKQPEEEDDPLGKLKNQKIVTCRICKGDHWTTKCPYKDTLAPLQEKLT 478

Query: 184 EQLGLSTGEKEKLPGELEPVQAAQSKTG------KYVPPSLRDGASR-RGESMQPNRRAD 236
           E         ++ P +  P  +A +  G      KYVPPS+RDGA++ RGESM  N+R D
Sbjct: 479 ED--------QRKPTDT-PAPSAAAGPGPKPAGTKYVPPSMRDGANKGRGESMA-NQRKD 628

Query: 237 DNATIRVTNLSEDTRETDLQELFRPFGSISRIYLAKDKTTGQSKGFAFISFHRREDAARA 296
           + ATIRVTNLSEDTRE+DLQELFRPFG ISRIYLAKDK TGQSKGFAFI+FHRREDA+RA
Sbjct: 629 EAATIRVTNLSEDTRESDLQELFRPFGPISRIYLAKDKVTGQSKGFAFINFHRREDASRA 808

Query: 297 IAGVSGFGYDHLILNVEWAKPS 318
           IAGVSGFGYDHLILNVEWAKPS
Sbjct: 809 IAGVSGFGYDHLILNVEWAKPS 874
>29459
          Length = 466

 Score = 80.5 bits (197), Expect = 8e-16,   Method: Compositional matrix adjust.
 Identities = 38/86 (44%), Positives = 55/86 (63%)
 Frame = -2

Query: 80  KIVRTFRIETRKASKAVARRKNWKKFGNSEFDPPGPNVATTTVSDDVSMTFITSKEDLNC 139
           K++RT++I  +   K VA+R+ W KFG S+ D PGPN  TT VS+++ M F+ SKED   
Sbjct: 246 KVIRTYKISKQVVPKTVAKRRTWTKFGESKNDKPGPNSQTTMVSEEIIMQFLNSKED--- 76

Query: 140 QEEEDPMNKLKGQKIVSCRICKGDHW 165
           ++  DP+     + I  CRIC G+HW
Sbjct: 75  EKANDPLLD-PTKNIAKCRICNGEHW 1
>00302
          Length = 927

 Score = 52.8 bits (125), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 28/80 (35%), Positives = 45/80 (56%)
 Frame = -1

Query: 236 DDNATIRVTNLSEDTRETDLQELFRPFGSISRIYLAKDKTTGQSKGFAFISFHRREDAAR 295
           D N  + +  LS  T+E  L+E+F  +G IS + +  D+ TG+S+GFAF+ F   EDA  
Sbjct: 474 DPNRCLGIFGLSLYTQERGLREVFGRYGHISEVQVVYDRQTGRSRGFAFVYFKSSEDAHE 295

Query: 296 AIAGVSGFGYDHLILNVEWA 315
           A    +G   D   + V+++
Sbjct: 294 AKDRCNGIEIDGRKIRVDFS 235
>17681
          Length = 964

 Score = 51.2 bits (121), Expect = 6e-07,   Method: Compositional matrix adjust.
 Identities = 25/62 (40%), Positives = 38/62 (61%)
 Frame = +2

Query: 241 IRVTNLSEDTRETDLQELFRPFGSISRIYLAKDKTTGQSKGFAFISFHRREDAARAIAGV 300
           I V +LS +     L+E F PFG IS   + +D  T +SKG+AF+SF ++ +A  AI  +
Sbjct: 38  IFVGDLSPEIETETLREAFAPFGEISNCRIVRDPQTMKSKGYAFVSFVKKAEAENAIQAM 217

Query: 301 SG 302
           +G
Sbjct: 218 NG 223

 Score = 33.9 bits (76), Expect = 0.093,   Method: Compositional matrix adjust.
 Identities = 19/43 (44%), Positives = 24/43 (55%)
 Frame = +2

Query: 255 LQELFRPFGSISRIYLAKDKTTGQSKGFAFISFHRREDAARAI 297
           + + F  FG I  + + KDK      GFAFI F  +E AARAI
Sbjct: 473 MHKHFMQFGPIQDVRVFKDK------GFAFIKFVTKEAAARAI 583
>25691
          Length = 768

 Score = 46.6 bits (109), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 31/94 (32%), Positives = 51/94 (54%), Gaps = 3/94 (3%)
 Frame = -2

Query: 230 QPNRRADDNATIRVTNLSEDTRETDLQELFRPFGSISRIYLAKDKTTGQSKGFAFISFHR 289
           +P+  +   A + ++ L +   + DL+ LF   G+I    +  D+TTG SKG  FI F +
Sbjct: 287 RPSCESIKGANLYISGLPKSLTQLDLENLFTDCGNIITSRILYDQTTGLSKGVGFIRFDQ 108

Query: 290 REDAARAIAGVSGFGYDHLI--LNVEWAK-PSTN 320
           R +A RAI  ++    D  I  + V++A  PS+N
Sbjct: 107 RIEAERAIQKLNNHIPDGCIDPITVKFANSPSSN 6

 Score = 45.4 bits (106), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 20/49 (40%), Positives = 32/49 (65%)
 Frame = -2

Query: 270 LAKDKTTGQSKGFAFISFHRREDAARAIAGVSGFGYDHLILNVEWAKPS 318
           L +DK TGQS G+ F+++ R+EDA +AI  ++G    +  + V  A+PS
Sbjct: 425 LIRDKPTGQSLGYGFVNYKRQEDADKAIHTLNGLRLQNKTIKVSLARPS 279
>03744
          Length = 3486

 Score = 46.2 bits (108), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 30/101 (29%), Positives = 48/101 (47%), Gaps = 1/101 (0%)
 Frame = -1

Query: 204  QAAQSKTGKYVPPSLRDGASRRG-ESMQPNRRADDNATIRVTNLSEDTRETDLQELFRPF 262
            Q A S    + P +    A+  G  S  P     D A + + +L ++  + DL ++F PF
Sbjct: 3324 QYAASFPNAFNPQAQMQQANSAGKHSEGPRVPGPDGANLFIYHLPQEFGDQDLMQMFMPF 3145

Query: 263  GSISRIYLAKDKTTGQSKGFAFISFHRREDAARAIAGVSGF 303
            G++    +  DK T  SK F F+S+     A  AI  ++GF
Sbjct: 3144 GNVVSAKVFIDKQTNLSKCFGFVSYDSPLAAQAAITSMNGF 3022
>02502
          Length = 1557

 Score = 46.2 bits (108), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 25/88 (28%), Positives = 41/88 (46%)
 Frame = -3

Query: 232  NRRADDNATIRVTNLSEDTRETDLQELFRPFGSISRIYLAKDKTTGQSKGFAFISFHRRE 291
            N+ +  N T+    ++    E  +   F+ FGSI  + + KDK      GFAFI F+ ++
Sbjct: 1462 NQSSQTNCTVYCGGVNNGLTEELMHNTFKDFGSILEVRIFKDK------GFAFIRFNNKD 1301

Query: 292  DAARAIAGVSGFGYDHLILNVEWAKPST 319
             A  AI  + G   +  ++   W K S 
Sbjct: 1300 AATNAICTIHGTVINDQVVRCSWGKESN 1217
>20488
          Length = 3281

 Score = 45.8 bits (107), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 22/67 (32%), Positives = 37/67 (55%)
 Frame = +2

Query: 237  DNATIRVTNLSEDTRETDLQELFRPFGSISRIYLAKDKTTGQSKGFAFISFHRREDAARA 296
            D A + + +L ++  + DL ++F PFG++    +  DK T  SK F F+S+     A  A
Sbjct: 2702 DGANLFIYHLPQEFGDQDLMQMFMPFGNVVSAKVFIDKQTNLSKCFGFVSYDSPLAAQAA 2881

Query: 297  IAGVSGF 303
            I  ++GF
Sbjct: 2882 ITSMNGF 2902
>30672
          Length = 877

 Score = 45.1 bits (105), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 25/86 (29%), Positives = 45/86 (52%)
 Frame = +3

Query: 230 QPNRRADDNATIRVTNLSEDTRETDLQELFRPFGSISRIYLAKDKTTGQSKGFAFISFHR 289
           QP +       + + NL+   +E D++  F  FG+IS + +   K   +S+GFAF+ F  
Sbjct: 378 QPKQELGKRCRLIIRNLAFKCKEADIRSHFGKFGTISEVTIPL-KQGDRSRGFAFVQFTE 554

Query: 290 REDAARAIAGVSGFGYDHLILNVEWA 315
            + A +AI+ ++G       + V+WA
Sbjct: 555 VKAAQKAISDMNGTAIMDRPVAVDWA 632

 Score = 36.2 bits (82), Expect = 0.016,   Method: Compositional matrix adjust.
 Identities = 18/57 (31%), Positives = 28/57 (49%)
 Frame = +3

Query: 240 TIRVTNLSEDTRETDLQELFRPFGSISRIYLAKDKTTGQSKGFAFISFHRREDAARA 296
           T+ V NL  +T    L E F   G +   ++   K  G+ +GF ++ F   EDA +A
Sbjct: 15  TLFVRNLPFETSNEKLLEAFEQVGPLKTAFVVAGKEPGKCRGFGYVQFSMLEDAIKA 185
>14637
          Length = 455

 Score = 44.7 bits (104), Expect = 6e-05,   Method: Compositional matrix adjust.
 Identities = 25/80 (31%), Positives = 42/80 (52%), Gaps = 5/80 (6%)
 Frame = -1

Query: 229 MQPNRRAD-----DNATIRVTNLSEDTRETDLQELFRPFGSISRIYLAKDKTTGQSKGFA 283
           MQ N  A      D + + + +L ++  + DL ++F PFG++    +  DK T  SK F 
Sbjct: 248 MQQNAAAKQSEGPDGSNLFIYHLPQEFGDQDLMQMFMPFGNVISAKVFIDKQTNLSKCFG 69

Query: 284 FISFHRREDAARAIAGVSGF 303
           F+S+     A  AI+ ++GF
Sbjct: 68  FVSYDSPMSAQDAISSMNGF 9
>11687
          Length = 676

 Score = 43.9 bits (102), Expect = 8e-05,   Method: Compositional matrix adjust.
 Identities = 22/74 (29%), Positives = 39/74 (52%), Gaps = 3/74 (4%)
 Frame = +3

Query: 237 DNATIRVTNLSEDTRETDLQELFRPFGSISRIYLAKDKTTGQSKGFAFISFHRRE---DA 293
           D+  + V  +  +  E +L+++F  +G +  + + +DK TGQSKG  F++F  R+   DA
Sbjct: 144 DSIKMFVGQIPRNMDENELRKMFEDYGPVHSLNILRDKNTGQSKGCCFVTFFTRKAALDA 323

Query: 294 ARAIAGVSGFGYDH 307
             A+  V      H
Sbjct: 324 QNALHNVKTMPMMH 365
>23322
          Length = 471

 Score = 43.9 bits (102), Expect = 9e-05,   Method: Compositional matrix adjust.
 Identities = 19/55 (34%), Positives = 34/55 (61%)
 Frame = -2

Query: 243 VTNLSEDTRETDLQELFRPFGSISRIYLAKDKTTGQSKGFAFISFHRREDAARAI 297
           V  + EDT E  +++ F  FG I+ + L +DK TG+++GF F++F   +   +A+
Sbjct: 398 VGGVKEDTTEDMIRDTFNEFGEITGVDLIQDKGTGKNRGFCFVTFGDHDSVDKAV 234
>14258
          Length = 1063

 Score = 43.9 bits (102), Expect = 9e-05,   Method: Compositional matrix adjust.
 Identities = 23/72 (31%), Positives = 37/72 (51%)
 Frame = +2

Query: 246 LSEDTRETDLQELFRPFGSISRIYLAKDKTTGQSKGFAFISFHRREDAARAIAGVSGFGY 305
           L+    + DL ++F PFG++    +  DK T  SK F F+S+     A  AI+ ++GF  
Sbjct: 83  LAPGVGDQDLMQMFMPFGNVISAKVFIDKQTNLSKCFGFVSYDSPMSAQDAISSMNGFQI 262

Query: 306 DHLILNVEWAKP 317
               L V+  +P
Sbjct: 263 GMKRLKVQLKRP 298
>12350
          Length = 975

 Score = 43.5 bits (101), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 22/56 (39%), Positives = 29/56 (51%)
 Frame = -2

Query: 243 VTNLSEDTRETDLQELFRPFGSISRIYLAKDKTTGQSKGFAFISFHRREDAARAIA 298
           V  L   + E DL+  F  FG +  + + KD  TGQSKGF FI F   E   + +A
Sbjct: 608 VLGLPWKSTEDDLRSYFSQFGDLLMVQVKKDPKTGQSKGFGFIRFAEYESQLKCMA 441
>31618
          Length = 716

 Score = 43.5 bits (101), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 35/96 (36%), Positives = 49/96 (51%), Gaps = 2/96 (2%)
 Frame = +1

Query: 216 PSLRDGASRRGESMQPNRRADDNAT--IRVTNLSEDTRETDLQELFRPFGSISRIYLAKD 273
           P+L+  A +    MQP R      T  + V  LS +T E +L++ F  +G I  I +  D
Sbjct: 229 PALQMAAQK----MQPLRVTSVMMTEKLFVGGLSWETTEKELRDHFGKYGEIESINVKTD 396

Query: 274 KTTGQSKGFAFISFHRREDAARAIAGVSGFGYDHLI 309
             TG+S+GFAFI F   E    AI  VS    +H+I
Sbjct: 397 PQTGRSRGFAFIVFTNTE----AIDQVSA-AEEHII 489
>03000
          Length = 778

 Score = 43.1 bits (100), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 19/55 (34%), Positives = 34/55 (61%)
 Frame = +3

Query: 243 VTNLSEDTRETDLQELFRPFGSISRIYLAKDKTTGQSKGFAFISFHRREDAARAI 297
           V  + EDT E  +++ F  FG I+ + L +DK TG+++GF F++F   +   +A+
Sbjct: 372 VGGVKEDTTEDMIRDTFNEFGEITGVDLIQDKGTGKNRGFCFVTFGDHDSVDKAV 536
>12506
          Length = 1056

 Score = 42.4 bits (98), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 25/63 (39%), Positives = 31/63 (49%)
 Frame = -3

Query: 255  LQELFRPFGSISRIYLAKDKTTGQSKGFAFISFHRREDAARAIAGVSGFGYDHLILNVEW 314
            L   F PFG I  I +  D  T + +GFAFI F   EDAA AI  ++        + V  
Sbjct: 1015 LHAAFLPFGDIVDIQIPLDYETEKHRGFAFIEFELAEDAAAAIDNMNESELFGRTIRVNL 836

Query: 315  AKP 317
            AKP
Sbjct: 835  AKP 827
>31310
          Length = 469

 Score = 41.6 bits (96), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 21/62 (33%), Positives = 36/62 (58%)
 Frame = -3

Query: 241 IRVTNLSEDTRETDLQELFRPFGSISRIYLAKDKTTGQSKGFAFISFHRREDAARAIAGV 300
           I V +++ + RE  +++ F PFG I  + L+ D  T + KGF+FI +   E A  A+  +
Sbjct: 317 IYVGSINFEIREDTIKQAFLPFGPIKSVNLSWDPITNKHKGFSFIEYDVPEAAQLALEQM 138

Query: 301 SG 302
           +G
Sbjct: 137 NG 132
>13457
          Length = 4857

 Score = 41.6 bits (96), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 21/74 (28%), Positives = 39/74 (52%)
 Frame = -1

Query: 229  MQPNRRADDNATIRVTNLSEDTRETDLQELFRPFGSISRIYLAKDKTTGQSKGFAFISFH 288
            + P     ++  + V  L++   E D+++LF P+G+I    + +D+  G SKG AF+ + 
Sbjct: 3438 LTPKMTIGEDRKLFVGMLNKQQTEEDVRQLFHPYGAIEECTILRDQN-GNSKGCAFVKYS 3262

Query: 289  RREDAARAIAGVSG 302
               +A  AI  + G
Sbjct: 3261 THSEAQAAINALHG 3220

 Score = 30.0 bits (66), Expect(2) = 0.063,   Method: Compositional matrix adjust.
 Identities = 12/47 (25%), Positives = 25/47 (53%)
 Frame = -3

Query: 234  RADDNATIRVTNLSEDTRETDLQELFRPFGSISRIYLAKDKTTGQSK 280
            R  +   + + +L +   + +L ++F PFG++    +  D+ T QSK
Sbjct: 2437 RGPEGCNLFIYHLPQXXGDAELAQMFVPFGNVISAKVYVDRATNQSK 2297

 Score = 23.1 bits (48), Expect(2) = 0.063,   Method: Compositional matrix adjust.
 Identities = 12/36 (33%), Positives = 17/36 (47%)
 Frame = -2

Query: 282  FAFISFHRREDAARAIAGVSGFGYDHLILNVEWAKP 317
            F F+SF     A  AI  ++GF      L V+  +P
Sbjct: 2294 FGFVSFDNPASAQAAIQAMNGFQIGMKRLKVQLKRP 2187
>33516
          Length = 449

 Score = 41.6 bits (96), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 20/47 (42%), Positives = 28/47 (59%)
 Frame = +1

Query: 241 IRVTNLSEDTRETDLQELFRPFGSISRIYLAKDKTTGQSKGFAFISF 287
           I V  LS DT +  LQ  F  FG I+   +  ++ TG+S+GF F+SF
Sbjct: 160 IFVGGLSWDTDQDSLQGYFSQFGEITDCIVMMNQQTGKSRGFGFVSF 300
>00556
          Length = 2189

 Score = 40.8 bits (94), Expect = 8e-04,   Method: Compositional matrix adjust.
 Identities = 22/68 (32%), Positives = 32/68 (47%)
 Frame = +3

Query: 236 DDNATIRVTNLSEDTRETDLQELFRPFGSISRIYLAKDKTTGQSKGFAFISFHRREDAAR 295
           D +  I +  L     E  ++EL   FG +    L +D  TG SKGFAF  +       +
Sbjct: 750 DSDHKIFMGGLPSYLSEDQMKELLLSFGPLKSFNLVRDNATGLSKGFAFCEYLDPSVTDQ 929

Query: 296 AIAGVSGF 303
           A AG++G 
Sbjct: 930 ACAGLNGM 953
>23250
          Length = 1617

 Score = 40.4 bits (93), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 20/69 (28%), Positives = 37/69 (53%), Gaps = 4/69 (5%)
 Frame = -1

Query: 223  SRRGESMQPNRRA----DDNATIRVTNLSEDTRETDLQELFRPFGSISRIYLAKDKTTGQ 278
            ++R E  Q N++A     D   + + ++     E  ++  F  FG ++R+ L++   TG 
Sbjct: 1395 NKRREDSQKNKKAKGRKSDRGVVYLGHIPAGFYEPQMKRFFSQFGRVTRLRLSRSTKTGG 1216

Query: 279  SKGFAFISF 287
            SKG+AF+ F
Sbjct: 1215 SKGYAFLEF 1189
>15371
          Length = 383

 Score = 40.4 bits (93), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 17/51 (33%), Positives = 30/51 (58%)
 Frame = -2

Query: 237 DNATIRVTNLSEDTRETDLQELFRPFGSISRIYLAKDKTTGQSKGFAFISF 287
           D A + + +L ++  + DL ++F PFG++    +  DK T  SK F F+S+
Sbjct: 163 DGANLFIYHLPQEFGDQDLMQMFMPFGNVVSAKVFIDKQTNLSKCFGFVSY 11
>02343
          Length = 1715

 Score = 39.7 bits (91), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 20/64 (31%), Positives = 33/64 (51%)
 Frame = -2

Query: 241  IRVTNLSEDTRETDLQELFRPFGSISRIYLAKDKTTGQSKGFAFISFHRREDAARAIAGV 300
            + +  LS +T + DL  L + FG+I+      D+TT + KG+ F+ F     A RA+  +
Sbjct: 1258 LYIRGLSPNTTDKDLVNLCQHFGTITSTKAIIDQTTNKCKGYGFVDFDAPGAAERAVQAL 1079

Query: 301  SGFG 304
               G
Sbjct: 1078 QAQG 1067
>11019
          Length = 552

 Score = 39.3 bits (90), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 19/55 (34%), Positives = 28/55 (50%)
 Frame = -1

Query: 233 RRADDNATIRVTNLSEDTRETDLQELFRPFGSISRIYLAKDKTTGQSKGFAFISF 287
           R       I V  LS  T   D++  F+ +G+I    L  DK T + +GFAF++F
Sbjct: 252 RMVTKTKKIFVGGLSSSTTVEDIKNYFKAYGTIEEATLMFDKVTSRHRGFAFVTF 88
>03059
          Length = 1154

 Score = 38.9 bits (89), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 19/63 (30%), Positives = 34/63 (53%), Gaps = 1/63 (1%)
 Frame = -2

Query: 241 IRVTNLSEDTRETDLQELFRPFGSISRIYLAKDKTT-GQSKGFAFISFHRREDAARAIAG 299
           + V  L+ +  +  +QE+F  +G+I  I L  D+     SKG A++ +   EDA +A+  
Sbjct: 664 VHVGRLTRNVNKDHIQEIFSLYGTIKFIDLPNDRIHPNTSKGHAYVEYENPEDAEKAVKY 485

Query: 300 VSG 302
           + G
Sbjct: 484 MDG 476
>11126
          Length = 1061

 Score = 38.5 bits (88), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 18/67 (26%), Positives = 35/67 (52%)
 Frame = -3

Query: 230 QPNRRADDNATIRVTNLSEDTRETDLQELFRPFGSISRIYLAKDKTTGQSKGFAFISFHR 289
           Q ++   D  ++ V N+       +L++ F   GS++R+ +  DK +G  KGFA++ F  
Sbjct: 657 QEDKIEADLRSVYVGNVDYGATAEELEQHFHGCGSVNRVTILCDKYSGHPKGFAYVEFAD 478

Query: 290 REDAARA 296
           ++    A
Sbjct: 477 KDSVVTA 457
>01937
          Length = 1320

 Score = 37.7 bits (86), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 18/47 (38%), Positives = 26/47 (55%)
 Frame = -1

Query: 241  IRVTNLSEDTRETDLQELFRPFGSISRIYLAKDKTTGQSKGFAFISF 287
            I V  LS  T   D +  F+ +G+I    L  DK T + +GFAF++F
Sbjct: 1209 IFVGGLSSSTTVEDXKNYFKAYGTIEEATLMFDKVTSRHRGFAFVTF 1069
>16427
          Length = 1313

 Score = 37.4 bits (85), Expect = 0.009,   Method: Compositional matrix adjust.
 Identities = 20/67 (29%), Positives = 33/67 (49%)
 Frame = +1

Query: 236 DDNATIRVTNLSEDTRETDLQELFRPFGSISRIYLAKDKTTGQSKGFAFISFHRREDAAR 295
           D    + V  L+E+  E  L+  F  FG I+   + +DK    S+GF F+++    DA  
Sbjct: 127 DRPGKLFVGGLAEEIDEKVLEREFSKFGRITESMVIRDKVRQVSRGFGFVTYENPMDAEE 306

Query: 296 AIAGVSG 302
           A+  + G
Sbjct: 307 AVKHMDG 327
>11108
          Length = 493

 Score = 36.6 bits (83), Expect = 0.013,   Method: Compositional matrix adjust.
 Identities = 16/56 (28%), Positives = 30/56 (53%)
 Frame = -1

Query: 232 NRRADDNATIRVTNLSEDTRETDLQELFRPFGSISRIYLAKDKTTGQSKGFAFISF 287
           +R  + +  + +  +  D  E  L ++F+PFGSI   +  K++   Q KG+ +I F
Sbjct: 313 HRMLNYSPKVFLGGIPWDISEQSLIQIFKPFGSIKVEWPGKEQQAAQPKGYVYIIF 146
>00781
          Length = 3170

 Score = 35.0 bits (79), Expect = 0.038,   Method: Compositional matrix adjust.
 Identities = 18/61 (29%), Positives = 32/61 (52%)
 Frame = -1

Query: 237  DNATIRVTNLSEDTRETDLQELFRPFGSISRIYLAKDKTTGQSKGFAFISFHRREDAARA 296
            D  T+ V    + T    +  +F   G+++ + L   KTT + KG+AF+ F   E+A +A
Sbjct: 2726 DARTVYVEGFHKFTSREWISRMFSKCGTVTYVSLPCFKTTREIKGYAFVEFQSPEEAVKA 2547

Query: 297  I 297
            +
Sbjct: 2546 V 2544
>01065
          Length = 1033

 Score = 34.7 bits (78), Expect = 0.046,   Method: Compositional matrix adjust.
 Identities = 22/80 (27%), Positives = 39/80 (48%)
 Frame = +2

Query: 241 IRVTNLSEDTRETDLQELFRPFGSISRIYLAKDKTTGQSKGFAFISFHRREDAARAIAGV 300
           I V +LS  T   +++E F+ FG I  +++ + + T      AF+ +   EDA +AI  +
Sbjct: 20  IHVGSLSSSTSTREIREEFKRFGDIIDLWMPRTQPT-----IAFVVYRYEEDAEKAIRRM 184

Query: 301 SGFGYDHLILNVEWAKPSTN 320
            G       + V  A+P + 
Sbjct: 185 DGESMHGRRVRVSLARPRSQ 244
>39789
          Length = 361

 Score = 34.7 bits (78), Expect = 0.059,   Method: Compositional matrix adjust.
 Identities = 22/59 (37%), Positives = 34/59 (57%)
 Frame = +1

Query: 239 ATIRVTNLSEDTRETDLQELFRPFGSISRIYLAKDKTTGQSKGFAFISFHRREDAARAI 297
           + + V NLS DT +  L++ F P  + +RI  AK + T + +GF F+ F   +DAA A 
Sbjct: 88  SVLFVGNLSYDTDQYSLKDAF-PGATAARI--AKFQDTQKPRGFGFVEFSTPDDAASAF 255
>00738
          Length = 1559

 Score = 34.3 bits (77), Expect = 0.077,   Method: Compositional matrix adjust.
 Identities = 22/77 (28%), Positives = 38/77 (49%)
 Frame = -2

Query: 241  IRVTNLSEDTRETDLQELFRPFGSISRIYLAKDKTTGQSKGFAFISFHRREDAARAIAGV 300
            I V +LS  T   +++E F+ FG I  +++ + + T      AF+ +   EDA +AI  +
Sbjct: 1261 IHVGSLSSSTSTREIREEFKRFGDIIDLWMPRTQPT-----IAFVVYRYEEDAEKAIRRM 1097

Query: 301  SGFGYDHLILNVEWAKP 317
             G       + V  A+P
Sbjct: 1096 DGESMHGRRVRVSLARP 1046
>19733
          Length = 723

 Score = 33.5 bits (75), Expect = 0.11,   Method: Compositional matrix adjust.
 Identities = 14/36 (38%), Positives = 23/36 (63%)
 Frame = +3

Query: 263 GSISRIYLAKDKTTGQSKGFAFISFHRREDAARAIA 298
           G ++ + L  DK TGQS+G AF+ F  ++ A + +A
Sbjct: 3   GELAYVRLVIDKVTGQSRGTAFVQFKEKDAADQCLA 110
>15503
          Length = 570

 Score = 32.7 bits (73), Expect = 0.18,   Method: Compositional matrix adjust.
 Identities = 24/98 (24%), Positives = 45/98 (45%)
 Frame = +1

Query: 217 SLRDGASRRGESMQPNRRADDNATIRVTNLSEDTRETDLQELFRPFGSISRIYLAKDKTT 276
           + +   S++G    P    + N  + V NL       ++ ++F  +G+I +I +     T
Sbjct: 91  NFKMAMSKKGNVRLP---PEVNRVLYVKNLPYKITAEEMYDIFGKYGAIRQIRVG---NT 252

Query: 277 GQSKGFAFISFHRREDAARAIAGVSGFGYDHLILNVEW 314
            ++KG AF+ +    DA  A   +SGF   +  L V +
Sbjct: 253 PETKGTAFVVYEDIFDAKNACDHLSGFNVCNRYLVVLY 366
>00029
          Length = 2204

 Score = 32.0 bits (71), Expect = 0.37,   Method: Compositional matrix adjust.
 Identities = 19/68 (27%), Positives = 37/68 (54%), Gaps = 2/68 (2%)
 Frame = -3

Query: 238  NATIRV--TNLSEDTRETDLQELFRPFGSISRIYLAKDKTTGQSKGFAFISFHRREDAAR 295
            N TI++   NL +DT   +L+ LF  +GS++   + K+        F F+   ++ +A  
Sbjct: 2145 NMTIKIFIGNLGDDTDPEELRALFEKYGSVAECDVLKN--------FGFVHMVKKGEADD 1990

Query: 296  AIAGVSGF 303
            AI+ ++G+
Sbjct: 1989 AISNLNGY 1966
>16016
          Length = 1364

 Score = 31.6 bits (70), Expect = 0.45,   Method: Compositional matrix adjust.
 Identities = 12/21 (57%), Positives = 17/21 (80%)
 Frame = -1

Query: 267 RIYLAKDKTTGQSKGFAFISF 287
           RI + KDK+TG+ +GF F+SF
Sbjct: 968 RINMIKDKSTGKFRGFCFVSF 906
>15994
          Length = 891

 Score = 30.8 bits (68), Expect = 0.68,   Method: Compositional matrix adjust.
 Identities = 22/80 (27%), Positives = 42/80 (52%), Gaps = 1/80 (1%)
 Frame = +3

Query: 235 ADDNATIRVTNLSEDT-RETDLQELFRPFGSISRIYLAKDKTTGQSKGFAFISFHRREDA 293
           A  N+ + V NL+  T  + D+  +F  +G+++ I +         KG+AF+ ++   +A
Sbjct: 291 ASKNSRVFVGNLNTFTLSKEDVDRIFGAYGAVTGISM--------HKGYAFVQYNHPGEA 446

Query: 294 ARAIAGVSGFGYDHLILNVE 313
            RA+A  +G  Y   IL++ 
Sbjct: 447 RRAVAFENGSSYGGQILDLN 506
>31364
          Length = 370

 Score = 29.3 bits (64), Expect = 2.2,   Method: Compositional matrix adjust.
 Identities = 16/55 (29%), Positives = 24/55 (43%)
 Frame = +2

Query: 90  RKASKAVARRKNWKKFGNSEFDPPGPNVATTTVSDDVSMTFITSKEDLNCQEEED 144
           R+ +  +  RK+W + G+     PG  + T T   DVS+       D N  E  D
Sbjct: 143 RQRNNWLDXRKDWTRXGHVHARSPGKVMTTATKQSDVSLLLSGILHD*NSHEIND 307
>36030
          Length = 479

 Score = 28.9 bits (63), Expect = 2.5,   Method: Compositional matrix adjust.
 Identities = 14/39 (35%), Positives = 23/39 (58%)
 Frame = +2

Query: 88  ETRKASKAVARRKNWKKFGNSEFDPPGPNVATTTVSDDV 126
           +TR+     A  ++ ++ G +E DPPGPN A T +  D+
Sbjct: 362 DTRRPGPDAA--QDVEEVGAAEMDPPGPNPANTVILRDL 472
>18706
          Length = 899

 Score = 28.9 bits (63), Expect = 2.8,   Method: Compositional matrix adjust.
 Identities = 19/51 (37%), Positives = 24/51 (47%)
 Frame = -3

Query: 241 IRVTNLSEDTRETDLQELFRPFGSISRIYLAKDKTTGQSKGFAFISFHRRE 291
           I VTNL     + D+ ELF   G + R  L        SKG A ++F  RE
Sbjct: 135 ILVTNLHASVTQDDIIELFGAIGPLKRAKL-------MSKGQAEVAFIHRE 4
>12037
          Length = 435

 Score = 28.5 bits (62), Expect = 4.1,   Method: Compositional matrix adjust.
 Identities = 15/42 (35%), Positives = 19/42 (45%)
 Frame = -3

Query: 100 KNWKKFGNSEFDPPGPNVATTTVSDDVSMTFITSKEDLNCQE 141
           K +++ G      PGP +  TT    V M F TS    NC E
Sbjct: 160 KEYEQLG------PGPKICFTTTDLLVHMAFTTSGVHCNCSE 53
>16077
          Length = 1159

 Score = 28.1 bits (61), Expect = 4.3,   Method: Compositional matrix adjust.
 Identities = 15/50 (30%), Positives = 23/50 (46%), Gaps = 9/50 (18%)
 Frame = +2

Query: 157 CRICKGD-HWTTRCPYKD--------TLGPMQKELAEQLGLSTGEKEKLP 197
           C +C+   HW   CP+KD        T   + +E+ E   L+   KE+ P
Sbjct: 251 CVVCESVFHWAKHCPHKDQRREEIKMTXAEIGEEMEEMCNLTLFTKEQKP 400
>21440
          Length = 603

 Score = 27.7 bits (60), Expect = 5.7,   Method: Compositional matrix adjust.
 Identities = 10/35 (28%), Positives = 20/35 (57%)
 Frame = -1

Query: 240 TIRVTNLSEDTRETDLQELFRPFGSISRIYLAKDK 274
            + + +L  +  ETD+ +L  PFG ++ + + K K
Sbjct: 342 VVHIRSLPHEVTETDVVQLGMPFGKMTNVLVLKQK 238
>31265
          Length = 540

 Score = 27.3 bits (59), Expect = 7.5,   Method: Compositional matrix adjust.
 Identities = 25/80 (31%), Positives = 37/80 (46%), Gaps = 3/80 (3%)
 Frame = +2

Query: 241 IRVTNLSEDTRETDLQELF-RPFGS--ISRIYLAKDKTTGQSKGFAFISFHRREDAARAI 297
           + V NL   T E  L+++F R  G   I R+   +D        +AF+ F  REDA +A+
Sbjct: 164 LXVRNLMLTTTEETLKDVFSRAAGGREIERVKKIRD--------YAFVHFRSREDAIKAM 319

Query: 298 AGVSGFGYDHLILNVEWAKP 317
               G   +   + V  AKP
Sbjct: 320 DVTDGSTIEGSQVEVVLAKP 379
>17775
          Length = 1282

 Score = 27.3 bits (59), Expect = 8.8,   Method: Compositional matrix adjust.
 Identities = 11/26 (42%), Positives = 18/26 (69%)
 Frame = -2

Query: 277 GQSKGFAFISFHRREDAARAIAGVSG 302
           G+S+GF F+SF   E A +A+  ++G
Sbjct: 540 GKSRGFGFVSFEEPEGAEKAVDEING 463
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6671571|ref|NP_031503.1| ADP-ribosylation factor 2
[Mus musculus]
         (181 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

09827                                                                 333   2e-92
08153                                                                 311   1e-85
10862                                                                 176   6e-45
32860                                                                 102   5e-24
33605                                                                 106   5e-24
11378                                                                 103   3e-23
18208                                                                  99   1e-21
06991                                                                  71   3e-13
19506                                                                  70   4e-13
18949                                                                  68   2e-12
15662                                                                  66   9e-12
11965                                                                  51   3e-07
34468                                                                  47   3e-06
29196                                                                  43   8e-05
14775                                                                  42   1e-04
13750                                                                  42   2e-04
08428                                                                  38   0.002
20877                                                                  37   0.005
19006                                                                  36   0.008
33374                                                                  36   0.009
33380                                                                  36   0.010
35581                                                                  36   0.010
33794                                                                  35   0.024
07465                                                                  34   0.032
26083                                                                  33   0.051
11728                                                                  33   0.053
13901                                                                  33   0.066
26536                                                                  31   0.25 
05468                                                                  31   0.34 
17511                                                                  30   0.53 
01972                                                                  27   3.2  
22540                                                                  27   3.5  
18743                                                                  27   5.7  
34359                                                                  27   6.7  
11257                                                                  26   8.3  
>09827
          Length = 1201

 Score =  333 bits (854), Expect = 2e-92,   Method: Compositional matrix adjust.
 Identities = 161/184 (87%), Positives = 169/184 (91%), Gaps = 3/184 (1%)
 Frame = -3

Query: 1    MGNVFEKLFKSL---FGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVE 57
            MGN F+K+F  L   FGKK+MRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVE
Sbjct: 1172 MGNAFQKIFSGLSFMFGKKDMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVE 993

Query: 58   YKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELTRMLAEDELR 117
            YKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSND+ERV EAREELTRML EDELR
Sbjct: 992  YKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDKERVQEAREELTRMLNEDELR 813

Query: 118  DAVLLVFVNKQDLPNAMNAAEITDKLGLHSLRQRNWYIQATCATSGDGLYEGLDWLSNQL 177
            DAVLLVF NKQDLP+AM  AEIT+KLGLH LR R WYIQ+TCAT+GDGLYEGLDWLSNQL
Sbjct: 812  DAVLLVFANKQDLPHAMATAEITEKLGLHGLRNRTWYIQSTCATTGDGLYEGLDWLSNQL 633

Query: 178  KNQK 181
            KN K
Sbjct: 632  KNNK 621
>08153
          Length = 1703

 Score =  311 bits (796), Expect = 1e-85,   Method: Compositional matrix adjust.
 Identities = 146/176 (82%), Positives = 163/176 (92%)
 Frame = +1

Query: 5   FEKLFKSLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNISFT 64
           F  LFK+LFGKKE+RILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNISFT
Sbjct: 46  FVSLFKNLFGKKEVRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNISFT 225

Query: 65  VWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELTRMLAEDELRDAVLLVF 124
           VWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRER+NEA+EEL RML ED+LRDA++LVF
Sbjct: 226 VWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERINEAKEELARMLNEDDLRDAIILVF 405

Query: 125 VNKQDLPNAMNAAEITDKLGLHSLRQRNWYIQATCATSGDGLYEGLDWLSNQLKNQ 180
            NKQDLPNA +A+E+T  LGL +L+ R WY+QATCATSGDG+YEGL+WLS  LK++
Sbjct: 406 ANKQDLPNAYSASEVTAHLGLANLKGRKWYMQATCATSGDGMYEGLEWLSTTLKHK 573
>10862
          Length = 2896

 Score =  176 bits (445), Expect = 6e-45,   Method: Compositional matrix adjust.
 Identities = 76/129 (58%), Positives = 98/129 (75%)
 Frame = -3

Query: 51   FNVETVEYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELTRM 110
                  + +   F VWDVGGQDKIRPLWRHY+  TQGLIFVVD  DR+R++EAR+EL R+
Sbjct: 2516 IQCRNCQLQECQFNVWDVGGQDKIRPLWRHYYTGTQGLIFVVDCADRDRIDEARQELHRI 2337

Query: 111  LAEDELRDAVLLVFVNKQDLPNAMNAAEITDKLGLHSLRQRNWYIQATCATSGDGLYEGL 170
            + + E+RDA++L+F NKQDLP+AM   EI +KLGL  LR RNWY+Q +CAT+GDGL EGL
Sbjct: 2336 INDREMRDAIILIFANKQDLPDAMKPHEIQEKLGLTRLRDRNWYVQPSCATTGDGLCEGL 2157

Query: 171  DWLSNQLKN 179
             WL++  K+
Sbjct: 2156 TWLTSNHKS 2130

 Score = 88.6 bits (218), Expect = 1e-18,   Method: Compositional matrix adjust.
 Identities = 40/56 (71%), Positives = 49/56 (87%)
 Frame = -1

Query: 7    KLFKSLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNIS 62
            KL   +FG KEMRILM+GLDAAGKTT+LYK+KLG+ VT IPT+GFNVETV +KN++
Sbjct: 2647 KLLSKIFGNKEMRILMLGLDAAGKTTLLYKMKLGQSVTXIPTVGFNVETVSFKNVN 2480
>32860
          Length = 330

 Score =  102 bits (255), Expect(2) = 5e-24,   Method: Compositional matrix adjust.
 Identities = 45/89 (50%), Positives = 64/89 (71%)
 Frame = +2

Query: 78  WRHYFQNTQGLIFVVDSNDRERVNEAREELTRMLAEDELRDAVLLVFVNKQDLPNAMNAA 137
           W  Y+ N++ +I V+DS DRER++  +EEL RMLA +ELR A LLVF NKQD+   M+AA
Sbjct: 8   WNTYYSNSEFIIMVIDSTDRERLSITKEELCRMLATEELRXAALLVFANKQDIKGCMSAA 187

Query: 138 EITDKLGLHSLRQRNWYIQATCATSGDGL 166
           EI+ +L L S++   W+IQA C  +G+G+
Sbjct: 188 EISXQLNLTSVKDHVWHIQACCGLTGEGV 274

 Score = 24.3 bits (51), Expect(2) = 5e-24,   Method: Compositional matrix adjust.
 Identities = 6/16 (37%), Positives = 14/16 (87%)
 Frame = +1

Query: 165 GLYEGLDWLSNQLKNQ 180
           GLY+GL+W+++ ++ +
Sbjct: 271 GLYQGLEWITSHIRRR 318
>33605
          Length = 888

 Score =  106 bits (265), Expect = 5e-24,   Method: Compositional matrix adjust.
 Identities = 47/92 (51%), Positives = 68/92 (73%)
 Frame = +1

Query: 15  KKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNISFTVWDVGGQDKI 74
           +KE+R+LM+GLD AGKTTIL K    +I T  PT+GFN++T+E++     VWDVGGQ  +
Sbjct: 490 EKEVRLLMLGLDNAGKTTILKKFNGEDIDTISPTLGFNIKTLEHRGFKLNVWDVGGQQSL 669

Query: 75  RPLWRHYFQNTQGLIFVVDSNDRERVNEAREE 106
           R  WR+YF++T GL++VVDS DR R+ + + +
Sbjct: 670 RSYWRNYFESTDGLVWVVDSADRMRIADCKRD 765
>11378
          Length = 1688

 Score =  103 bits (258), Expect = 3e-23,   Method: Compositional matrix adjust.
 Identities = 51/134 (38%), Positives = 84/134 (62%)
 Frame = +3

Query: 15  KKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNISFTVWDVGGQDKI 74
           KK  +++ +GLD AGKTT+L+ LK  ++   +PT+    E +    + FT +D+GG  + 
Sbjct: 315 KKSGKLVFLGLDNAGKTTLLHMLKDDKMAQHVPTLHPTSEELSMGGMRFTTFDLGGHRQA 494

Query: 75  RPLWRHYFQNTQGLIFVVDSNDRERVNEAREELTRMLAEDELRDAVLLVFVNKQDLPNAM 134
           R +W+ YF    G++F+VD +DRER+ EA+ EL  ++ ++++ +A +LV  NK D P A 
Sbjct: 495 RRVWKDYFPAVDGIVFLVDVHDRERLVEAKAELDSLMTDEQVANAPILVLGNKIDKPGAA 674

Query: 135 NAAEITDKLGLHSL 148
           +  EI    GL+SL
Sbjct: 675 SEEEIRHWFGLNSL 716
>18208
          Length = 458

 Score = 98.6 bits (244), Expect = 1e-21,   Method: Compositional matrix adjust.
 Identities = 43/88 (48%), Positives = 64/88 (72%)
 Frame = -1

Query: 16  KEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNISFTVWDVGGQDKIR 75
           +E+RIL++GLD AGKTT+L +L   +     PT GFN+++V+ K     VWD+GGQ +IR
Sbjct: 305 RELRILLLGLDNAGKTTLLKQLASEDPSHITPTQGFNIKSVQSKGFKLNVWDIGGQRRIR 126

Query: 76  PLWRHYFQNTQGLIFVVDSNDRERVNEA 103
           P W++YF+NT  LI+V+DS+D +R+ E 
Sbjct: 125 PYWKNYFENTDLLIYVIDSSDTKRMEET 42
>06991
          Length = 1860

 Score = 70.9 bits (172), Expect = 3e-13,   Method: Compositional matrix adjust.
 Identities = 32/67 (47%), Positives = 44/67 (65%)
 Frame = -2

Query: 111  LAEDELRDAVLLVFVNKQDLPNAMNAAEITDKLGLHSLRQRNWYIQATCATSGDGLYEGL 170
            L EDEL+ ++L+VF NKQD+  AM   E+ + LGL  L+ R + I  T A  G+GL E +
Sbjct: 1859 LEEDELKKSILMVFANKQDIEGAMTVTEVANSLGLPGLKNRKYQIFKTSAVKGEGLDEAM 1680

Query: 171  DWLSNQL 177
            +WLSN L
Sbjct: 1679 EWLSNSL 1659
>19506
          Length = 421

 Score = 70.1 bits (170), Expect = 4e-13,   Method: Compositional matrix adjust.
 Identities = 32/51 (62%), Positives = 42/51 (82%)
 Frame = -3

Query: 11  SLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNI 61
           +LF +K + ++  GLDAAGKTT+LY LKLGE+VTTIPTIGFNVET++   +
Sbjct: 155 TLFRQKPVTVIYFGLDAAGKTTLLYNLKLGEVVTTIPTIGFNVETLDMNRV 3
>18949
          Length = 414

 Score = 68.2 bits (165), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 31/83 (37%), Positives = 50/83 (60%)
 Frame = +3

Query: 47  PTIGFNVETVEYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREE 106
           PT     E +    ++FT +D+GG  + R +W+ YF    G++F+VD +D ER+ EA+ E
Sbjct: 15  PTGLPTSEELSMGGMTFTTFDLGGHRQARRVWKDYFPAVDGIVFIVDVHDTERITEAKAE 194

Query: 107 LTRMLAEDELRDAVLLVFVNKQD 129
           L  +L +D++ D  +LV  NK D
Sbjct: 195 LDSLLRDDQIADIPVLVLGNKMD 263
>15662
          Length = 455

 Score = 65.9 bits (159), Expect = 9e-12,   Method: Compositional matrix adjust.
 Identities = 31/76 (40%), Positives = 48/76 (63%)
 Frame = +2

Query: 73  KIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELTRMLAEDELRDAVLLVFVNKQDLPN 132
           + R +W+ YF    G++F+VD +DRER  EA+ EL  ++ ++++ +A +LV  NK D P 
Sbjct: 2   QARRVWKDYFPAVDGIVFLVDVHDRERFVEAKAELDSLMTDEQVANAPILVLGNKIDKPG 181

Query: 133 AMNAAEITDKLGLHSL 148
           A +  EI    GLHSL
Sbjct: 182 AASEDEIRHWFGLHSL 229
>11965
          Length = 3256

 Score = 50.8 bits (120), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 39/155 (25%), Positives = 65/155 (41%), Gaps = 32/155 (20%)
 Frame = +1

Query: 44  TTIPTIGFNVETVEYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEA 103
           T + T G       +KN++F ++DVGGQ   R  W H F++   +IF V  ++ ++V   
Sbjct: 133 TRVKTTGIVEVHFSFKNLNFKLFDVGGQRSERKKWIHCFEDVTAIIFCVAMSEYDQVLHE 312

Query: 104 REELTRMLAEDELRDAV----------LLVFVNKQDL--------PNAMNAAEITDKLGL 145
            E   RM    +L D++          +++F+NK+DL        P  +   E T K   
Sbjct: 313 DETTNRMQESLKLFDSICNNKWFTDTSIILFLNKKDLFEEKIKKSPLTVCFPEYTGKQTY 492

Query: 146 HSL--------------RQRNWYIQATCATSGDGL 166
             +               Q+  Y   TCAT  + +
Sbjct: 493 EEVAAYIQAQFEAKNKSSQKEIYCHQTCATDTNNI 597
>34468
          Length = 1502

 Score = 47.4 bits (111), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 24/85 (28%), Positives = 47/85 (55%), Gaps = 6/85 (7%)
 Frame = +1

Query: 15  KKEMRILMVGLDAAGKTTILYKLKLGEIV-TTIPTIGFNVE----TVEYKNISFTVWDVG 69
           ++  +I+++G    GKT + Y+  LG+    T  TIG +       V+ +++   +WD  
Sbjct: 487 RRIFKIIVIGDSNVGKTCLTYRFCLGKFPDKTEATIGVDFREKSIQVDSEHLKLQLWDTA 666

Query: 70  GQDKIR-PLWRHYFQNTQGLIFVVD 93
           GQ++ R  + +HY++N   ++FV D
Sbjct: 667 GQERFRKSMVQHYYRNVHAVVFVYD 741
>29196
          Length = 431

 Score = 42.7 bits (99), Expect = 8e-05,   Method: Compositional matrix adjust.
 Identities = 21/63 (33%), Positives = 35/63 (55%)
 Frame = -2

Query: 59  KNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELTRMLAEDELRD 118
           KN++F ++DVGGQ   R  W H F++   +IF V  ++ ++V    E   RM    +L D
Sbjct: 229 KNLNFKLFDVGGQRSERKKWIHCFEDVTAIIFCVAMSEYDQVLHEDETTNRMQESLKLFD 50

Query: 119 AVL 121
           ++ 
Sbjct: 49  SIC 41
>14775
          Length = 380

 Score = 42.0 bits (97), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 23/70 (32%), Positives = 36/70 (51%), Gaps = 6/70 (8%)
 Frame = -2

Query: 30  KTTILYKLKLGEIV-TTIPTIG-----FNVETVEYKNISFTVWDVGGQDKIRPLWRHYFQ 83
           KT +L + + G  +  T+PTI      FN    +  N+ +T+WD GG +  R LW  +F+
Sbjct: 379 KTCLLRRYQKGFFMDRTMPTIAVLCSEFNESRTDPLNVRYTLWDTGGAETYRSLWVSHFR 200

Query: 84  NTQGLIFVVD 93
             Q  + V D
Sbjct: 199 GAQVALLVYD 170
>13750
          Length = 503

 Score = 41.6 bits (96), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 23/70 (32%), Positives = 36/70 (51%), Gaps = 6/70 (8%)
 Frame = -2

Query: 30  KTTILYKLKLGEIV-TTIPTIG-----FNVETVEYKNISFTVWDVGGQDKIRPLWRHYFQ 83
           KT +L + + G  +  T+PTI      FN    +  N+ +T+WD GG +  R LW  +F+
Sbjct: 502 KTCLLRRYQKGFFMDRTMPTIAVLCSEFNESRTDPLNVRYTLWDTGGAETYRSLWVSHFR 323

Query: 84  NTQGLIFVVD 93
             Q  + V D
Sbjct: 322 GAQVALLVYD 293
>08428
          Length = 1109

 Score = 38.1 bits (87), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 29/120 (24%), Positives = 55/120 (45%), Gaps = 5/120 (4%)
 Frame = -3

Query: 16   KEMRILMVGLDAAGKTTILYKLKLGEIVTTI-PTIGFNVET----VEYKNISFTVWDVGG 70
            +++++ ++G    GK++I+ +   G    +   TIG +  +    V+     F +WD  G
Sbjct: 1074 RDVKVCLLGDSGVGKSSIVLRFVTGSYRPSQESTIGASFMSKSLVVDGAGYRFQIWDTAG 895

Query: 71   QDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELTRMLAEDELRDAVLLVFVNKQDL 130
            Q+K R L   Y++     + V D   R R  ++ +   + L      + VL +  NK DL
Sbjct: 894  QEKFRALAPMYYRGAAAAVIVYDVT-RPRTFKSVKSWIQELRSFGPPNIVLAIAGNKCDL 718
>20877
          Length = 381

 Score = 36.6 bits (83), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 16/16 (100%), Positives = 16/16 (100%)
 Frame = -1

Query: 164 DGLYEGLDWLSNQLKN 179
           DGLYEGLDWLSNQLKN
Sbjct: 381 DGLYEGLDWLSNQLKN 334
>19006
          Length = 568

 Score = 36.2 bits (82), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 40/151 (26%), Positives = 68/151 (45%), Gaps = 12/151 (7%)
 Frame = -2

Query: 11  SLFGKKEMRILMVGLDAAGKTTILY---KLKLGEIVTTIPTIGFNVET---VEYKNISFT 64
           S  G  + ++++VG  A GKT +L    K +  E+   +PT+  N      V+ K +   
Sbjct: 456 STNGCHKEKLVIVGDGACGKTCLLIVFSKDQFPEVY--VPTVFENYVADIEVDSKQVELA 283

Query: 65  VWDVGGQ---DKIRPLWRHYFQNTQGLI--FVVDSNDR-ERVNEAREELTRMLAEDELRD 118
           +WD  GQ   D++RPL    + +T  ++  F +DS D  E + E      R        +
Sbjct: 282 LWDTAGQEDYDRLRPL---SYPDTDVILMCFSIDSPDSLENIPEKWTPEVRHFCP----N 124

Query: 119 AVLLVFVNKQDLPNAMNAAEITDKLGLHSLR 149
             +++  NK+DL N  N      K+    +R
Sbjct: 123 VPIILVGNKKDLRNDENTKRELMKMKQEPVR 31
>33374
          Length = 489

 Score = 35.8 bits (81), Expect = 0.009,   Method: Compositional matrix adjust.
 Identities = 21/75 (28%), Positives = 36/75 (48%), Gaps = 3/75 (4%)
 Frame = +1

Query: 61  ISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAR---EELTRMLAEDELR 117
           + F +WD  GQ++   L   Y++  Q  I V D  +++    A+   +EL R  +     
Sbjct: 175 VKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNQDTFGRAKTWVKELQRQASP---- 342

Query: 118 DAVLLVFVNKQDLPN 132
           + V+ +  NK DL N
Sbjct: 343 NIVIALAGNKADLAN 387
>33380
          Length = 282

 Score = 35.8 bits (81), Expect = 0.010,   Method: Compositional matrix adjust.
 Identities = 20/74 (27%), Positives = 35/74 (47%)
 Frame = +3

Query: 59  KNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELTRMLAEDELRD 118
           K +   +WD  GQ++ R +   Y++   G I + D  + E  N  ++  T++        
Sbjct: 54  KRVKLQIWDTAGQERYRTITTAYYRGAMGFILMYDVTNEESFNAVQDWCTQIKTYSWDNA 233

Query: 119 AVLLVFVNKQDLPN 132
            V+LV  NK DL +
Sbjct: 234 QVVLVG-NKCDLED 272
>35581
          Length = 364

 Score = 35.8 bits (81), Expect = 0.010,   Method: Compositional matrix adjust.
 Identities = 22/92 (23%), Positives = 47/92 (51%), Gaps = 7/92 (7%)
 Frame = +2

Query: 18  MRILMVGLDAAGKTTILYKLK----LGEIVTTIPTIGFNVETVEYKN---ISFTVWDVGG 70
            + +++G    GKT +L +L     L   +T++ T    + TV   +    S  +WD  G
Sbjct: 47  FKCVLLGDAGVGKTCLLNRLATDKFLDSPLTSLTTASL-LTTVTLTSGVMASVDLWDTAG 223

Query: 71  QDKIRPLWRHYFQNTQGLIFVVDSNDRERVNE 102
           Q++ R L   Y+++T+ ++ V D+  + ++ +
Sbjct: 224 QERYRSLTSSYYRDTKAVLIVYDAEHKLKLTD 319
>33794
          Length = 779

 Score = 34.7 bits (78), Expect = 0.024,   Method: Compositional matrix adjust.
 Identities = 15/48 (31%), Positives = 24/48 (50%), Gaps = 2/48 (4%)
 Frame = -1

Query: 48  TIGFNVETV--EYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVD 93
           T+ +   T+  E K +   +WD  GQ +   + R Y +  QG+I V D
Sbjct: 695 TVAYKTTTILLEGKRVKLQIWDTSGQGRFCTIIRSYSRGAQGIILVYD 552
>07465
          Length = 1103

 Score = 34.3 bits (77), Expect = 0.032,   Method: Compositional matrix adjust.
 Identities = 19/72 (26%), Positives = 38/72 (52%)
 Frame = +3

Query: 59  KNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELTRMLAEDELRD 118
           +++   +WD  GQ++   + + Y++  Q  +    + DR+   EA E   R + EDE+ +
Sbjct: 339 EDVRLMLWDTAGQEEFDAITKAYYRGAQACVLAFSTVDRDSF-EALETWKRKV-EDEVGE 512

Query: 119 AVLLVFVNKQDL 130
             +++  NK DL
Sbjct: 513 IGMVIVQNKIDL 548
>26083
          Length = 432

 Score = 33.5 bits (75), Expect = 0.051,   Method: Compositional matrix adjust.
 Identities = 19/83 (22%), Positives = 41/83 (49%), Gaps = 5/83 (6%)
 Frame = +1

Query: 16  KEMRILMVGLDAAGKTTILYKLKLGEIVTTI-PTIGFNVET----VEYKNISFTVWDVGG 70
           ++ +++ +G  + GKT+++ +        T   TIG +  +    +E + I   +WD  G
Sbjct: 73  RKFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTIRLQLWDTAG 252

Query: 71  QDKIRPLWRHYFQNTQGLIFVVD 93
           Q++ R L   Y +++   + V D
Sbjct: 253 QERFRSLIPSYIRDSSVAVVVYD 321
>11728
          Length = 635

 Score = 33.5 bits (75), Expect = 0.053,   Method: Compositional matrix adjust.
 Identities = 23/73 (31%), Positives = 35/73 (47%), Gaps = 7/73 (9%)
 Frame = -1

Query: 12  LFGKKEMRILMVGLDAAGKTTILYKLKLGEIV-TTIPTIGFNVET---VEYKNISFTVWD 67
            F  + ++ ++VG  A GKT +L            IPT+  N      V+ K I+  +WD
Sbjct: 506 FFNMQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDSKPINLGLWD 327

Query: 68  VGGQ---DKIRPL 77
             GQ   D++RPL
Sbjct: 326 TAGQEDYDRLRPL 288
>13901
          Length = 962

 Score = 33.1 bits (74), Expect = 0.066,   Method: Compositional matrix adjust.
 Identities = 18/90 (20%), Positives = 41/90 (45%), Gaps = 14/90 (15%)
 Frame = -3

Query: 18  MRILMVGLDAAGKTTIL-----------YKLKLGEIVTTIPTIGFNVETVEYK---NISF 63
            +++++G    GKT+ +           YK+ +G        + F ++ + +    NI  
Sbjct: 285 FKVIIIGDPTVGKTSFVQRYVNDSFRRDYKMTIG--------VDFALKVIRWSDKCNIKL 130

Query: 64  TVWDVGGQDKIRPLWRHYFQNTQGLIFVVD 93
            +WD+ GQ++   + R Y+++    I + D
Sbjct: 129 QLWDIAGQERFTSMTRVYYKDAHACIVMFD 40
>26536
          Length = 829

 Score = 31.2 bits (69), Expect = 0.25,   Method: Compositional matrix adjust.
 Identities = 32/121 (26%), Positives = 52/121 (42%), Gaps = 9/121 (7%)
 Frame = +2

Query: 59  KNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELTRMLAEDELRD 118
           + +S+T  D  GQ++   +  HY ++  G I V    D     EA E + R L   +   
Sbjct: 122 RRVSWTFLDTAGQEEYSSMREHYTRSGDGFIVVYSVTDVTSFQEA-EAVFRWLTRFQDET 298

Query: 119 AVLLVFV-NKQDLPN-----AMNAAEITDKLGLHSLRQRNWYIQATCATSGDG---LYEG 169
           ++  V   NK DL +          ++ D+LG+        Y + T A +GD    +Y G
Sbjct: 299 SIHAVLCGNKTDLTSDRKVTPEEGRKMADRLGM-------LYFE-TSAKTGDNVSQVYHG 454

Query: 170 L 170
           L
Sbjct: 455 L 457
>05468
          Length = 1558

 Score = 30.8 bits (68), Expect = 0.34,   Method: Compositional matrix adjust.
 Identities = 23/92 (25%), Positives = 44/92 (47%), Gaps = 13/92 (14%)
 Frame = -3

Query: 15   KKE--MRILMVGLDAAGKTTIL-----------YKLKLGEIVTTIPTIGFNVETVEYKNI 61
            KKE   +IL++G    GKT+I+           Y+  +G +   +  + ++ +T+    I
Sbjct: 1553 KKEHLYKILVIGELGTGKTSIIKRYVHQFFSQHYRATIG-VDFALKVLNWDADTL----I 1389

Query: 62   SFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVD 93
               +WD+ GQ++   + R Y++   G   V D
Sbjct: 1388 RLQLWDIAGQERFGNMTRVYYKEAVGAFVVFD 1293
>17511
          Length = 483

 Score = 30.0 bits (66), Expect = 0.53,   Method: Compositional matrix adjust.
 Identities = 24/127 (18%), Positives = 54/127 (42%), Gaps = 14/127 (11%)
 Frame = -3

Query: 18  MRILMVGLDAAGKTTIL-----------YKLKLGEIVTTIPTIGFNVETVEYKNISFTVW 66
           ++++++G    GKT+++           YK  +G    T   +      V+ + ++  +W
Sbjct: 364 LKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVM------VDDRLVTMQIW 203

Query: 67  DVGGQDKIRPLWRHYFQNTQGLIFVVD---SNDRERVNEAREELTRMLAEDELRDAVLLV 123
           D  GQ++ + L   +++     + V D    N    ++  R+E     +  +  +   +V
Sbjct: 202 DTAGQERFQSLGVAFYRGADCCVLVFDVTMPNTFRSLDSWRDEFLIQASPRDPENFPFVV 23

Query: 124 FVNKQDL 130
             NK DL
Sbjct: 22  IGNKIDL 2
>01972
          Length = 2359

 Score = 27.3 bits (59), Expect = 3.2,   Method: Compositional matrix adjust.
 Identities = 15/56 (26%), Positives = 24/56 (42%), Gaps = 4/56 (7%)
 Frame = +3

Query: 46  IPTIGFNVETVEYKN----ISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDR 97
           + T+G  V  + +      + F VWD  GQ+K   L   Y+   Q  + + D   R
Sbjct: 390 VATLGVEVHPLLFHTSRGKLKFNVWDTAGQEKFGGLRDGYYIQGQCAVIMFDVTSR 557
>22540
          Length = 337

 Score = 27.3 bits (59), Expect = 3.5,   Method: Compositional matrix adjust.
 Identities = 11/14 (78%), Positives = 13/14 (92%)
 Frame = +2

Query: 166 LYEGLDWLSNQLKN 179
           LYEGLDWLSN+L +
Sbjct: 2   LYEGLDWLSNELAS 43
>18743
          Length = 465

 Score = 26.6 bits (57), Expect = 5.7,   Method: Compositional matrix adjust.
 Identities = 22/50 (44%), Positives = 23/50 (46%), Gaps = 6/50 (12%)
 Frame = +2

Query: 20  ILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNV------ETVEYKNISF 63
           I MVGL A GKT I  KL        I T  FNV       T  YKN +F
Sbjct: 131 IAMVGLPARGKTYISKKLTRYLNWIGISTRAFNVGEYRRAATNSYKNHNF 280
>34359
          Length = 1042

 Score = 26.6 bits (57), Expect = 6.7,   Method: Compositional matrix adjust.
 Identities = 15/56 (26%), Positives = 24/56 (42%), Gaps = 4/56 (7%)
 Frame = +3

Query: 46  IPTIGFNVETVEYKN----ISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDR 97
           + T+G  V  +++      + F VWD  GQ+K   L   Y+      I + D   R
Sbjct: 138 VATLGVEVHPLQFNTSRGLLRFNVWDTAGQEKFGGLRDGYYIQGTCAIIMFDVTSR 305
>11257
          Length = 1102

 Score = 26.2 bits (56), Expect = 8.3,   Method: Compositional matrix adjust.
 Identities = 17/95 (17%), Positives = 44/95 (46%), Gaps = 10/95 (10%)
 Frame = -2

Query: 46   IPTIGFNVETVEYKNI-----SFT--VWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRE 98
            +P++  +   V +K++     +FT  +WD  GQ++ + L   +++ T   +     ++ +
Sbjct: 1092 MPSLPHDRRGVPHKDVVVDGETFTMQIWDTAGQERYKSLRTPFYRGTDCCLLTFSVDNLK 913

Query: 99   RVNEAREELTRMLAEDELRDAVLLVFV---NKQDL 130
             +    +     +   +++D+    FV   NK D+
Sbjct: 912  SLQSLSDWYDEFVNYADIQDSASFPFVIIGNKADI 808
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|74218637|dbj|BAE25199.1| unnamed protein product [Mus
musculus]
         (1453 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

13259                                                                 337   2e-92
30880                                                                  92   1e-18
17703                                                                  56   9e-08
11801                                                                  32   1.6  
06426                                                                  31   3.7  
>13259
          Length = 1751

 Score =  337 bits (865), Expect = 2e-92,   Method: Compositional matrix adjust.
 Identities = 162/249 (65%), Positives = 202/249 (81%)
 Frame = +2

Query: 8   SLQRPRYGSIVDDERLSAEEMDERRRQNIAYEYLCHLEEAKRWMEVCLVXXXXXXXXXXX 67
           + ++P Y ++ +D RL+A+EMDE+R++NIAYEYLCHLEEAK W++ C+            
Sbjct: 275 AAEKPHYRTL-EDARLTADEMDEQRKRNIAYEYLCHLEEAKVWIQACINEDLPPTTELEE 451

Query: 68  GLRNGVYLAKLAKFFAPKMVSEKKIYDVEQTRYKKSGLHFRHTDNTVQWLRAMEAIGLPK 127
           GLRNGV+LAKL  FFA  +VS KKIYD +QTRYK  GLHFRHTDN   WLRAME +GLP 
Sbjct: 452 GLRNGVFLAKLGHFFAAXVVSLKKIYDKDQTRYKSRGLHFRHTDNINHWLRAMEEVGLPT 631

Query: 128 IFYPETTDVYDRKNIPRMIYCIHALSLYLFKLGIAPQIQDLLGKVDFTEEEISNMRKELE 187
           IFYPETTD+YDRKNIPR +YC+HALSLYLFKLG+APQIQDL GK++FTEEEIS MR EL+
Sbjct: 632 IFYPETTDIYDRKNIPRAVYCVHALSLYLFKLGLAPQIQDLYGKINFTEEEISAMRSELD 811

Query: 188 KYGIQMPAFSKIGGILANELSVDEAALHAAVIAINEAIEKGVAKQTIITLRNPNAVLTCV 247
           KYGIQMPAFSKIGGILANE++VD+AALHAA+IAINEA+++ VA  T+  ++N +A+L  +
Sbjct: 812 KYGIQMPAFSKIGGILANEMTVDDAALHAAIIAINEAVDQQVAADTMTAMQNASAMLVNL 991

Query: 248 DDSLSQEYQ 256
           D  ++Q YQ
Sbjct: 992 DPDVAQHYQ 1018

 Score = 43.1 bits (100), Expect = 8e-04,   Method: Compositional matrix adjust.
 Identities = 65/286 (22%), Positives = 116/286 (40%), Gaps = 7/286 (2%)
 Frame = +2

Query: 321  NTLLALKKPEAQLPAVYPFAAVMYQNELFNLQKQNTSNYLAHEELLIAVEMLSAVALLNQ 380
            +T+ A++   A L  + P  A  YQ++L++ +         H +  +A   L  +  L Q
Sbjct: 944  DTMTAMQNASAMLVNLDPDVAQHYQDQLYSAK---------HTKAEVARNKLEEIKSLAQ 1096

Query: 381  ALESSDLVAV-QNQLRSPTIGFN------NLDEAHVDRYADALLSVKQEALSQGQDTLSW 433
             L++  L+    +++   T G +      N     +D        V  E L+Q       
Sbjct: 1097 RLQNPSLILYGTHEMTQGTRGGDGMPVKXNGQPGSIDPERSYDHDVYDELLTQA------ 1258

Query: 434  NEIQNCIDMINNQIQEENDRMVVLGYINEAIDAGNXXXXXXXXXXXXANIRDVDPDCAQH 493
             EIQ  I+ +N          V L  +N+A+  G+              +RDV  D A++
Sbjct: 1259 -EIQGXINKVNIS--------VALDRVNDALLKGDLSLLLAALRVPSLGLRDVTDDNAEY 1411

Query: 494  YQDVLFYTKSQKLGDPKNVSKVLWLDEIQQAINEANVDENRAKQWVTLVVDVNECLDRKQ 553
            Y   L      K  +       L  +E+QQAIN+AN++ +   +    V  VN  +D  +
Sbjct: 1412 YAAKLREAHELKKNNNNGEEXQLDKEELQQAINQANLEASAQYEKEQAVKAVNAAIDSGE 1591

Query: 554  SDHILTALKSSPSNIHNILPECANKYYDTLVKAKESKTDNESSEGS 599
            +D +L A ++S +    +       Y + L   K  K ++   EG+
Sbjct: 1592 ADQVLKAFQNSAALFPQVYDFAGXLYLEELACIKAEKQEDLDQEGN 1729

 Score = 38.1 bits (87), Expect = 0.027,   Method: Compositional matrix adjust.
 Identities = 40/106 (37%), Positives = 53/106 (50%), Gaps = 1/106 (0%)
 Frame = +2

Query: 281  ERDAYEELLTQAEIQSNISTVNRMAAVDHINAVLQEGDPENTLLALKKPEAQLPAVYPFA 340
            + D Y+ELLTQAEIQ  I+ VN   A+D +N  L +GD    L AL+ P   L  V    
Sbjct: 1223 DHDVYDELLTQAEIQGXINKVNISVALDRVNDALLKGDLSLLLAALRVPSLGLRDVTDDN 1402

Query: 341  AVMYQNELFNLQKQNTSNYLAHEELLIAVEMLSAVALLNQA-LESS 385
            A  Y  +L    +   +N    E  L   E+  A+   NQA LE+S
Sbjct: 1403 AEYYAAKLREAHELKKNNNNGEEXQLDKEELQQAI---NQANLEAS 1531
>30880
          Length = 671

 Score = 92.0 bits (227), Expect = 1e-18,   Method: Compositional matrix adjust.
 Identities = 51/193 (26%), Positives = 97/193 (50%)
 Frame = +3

Query: 431 LSWNEIQNCIDMINNQIQEENDRMVVLGYINEAIDAGNXXXXXXXXXXXXANIRDVDPDC 490
           L+  +I + I+ ++ ++QEE +R+  +  INEAID G+            A + ++DP  
Sbjct: 96  LTHADIVDTIETVHQKVQEEQERIKAIESINEAIDKGDESETLASLQMPSAKLSNIDPLQ 275

Query: 491 AQHYQDVLFYTKSQKLGDPKNVSKVLWLDEIQQAINEANVDENRAKQWVTLVVDVNECLD 550
           A HYQ +L   K +K    ++   VLWL+EIQ  ++ AN +     +    +  VNE L 
Sbjct: 276 AVHYQVLLAKEKDRKAEKTQDEGAVLWLEEIQSTVDHANRNAEEGLKMSRGIQAVNEALA 455

Query: 551 RKQSDHILTALKSSPSNIHNILPECANKYYDTLVKAKESKTDNESSEGSWVTLNVQEKYN 610
              +D ++  L +  +  H++  EC   Y + L + ++ K ++  S   W+   V +   
Sbjct: 456 TDDTDSLVAGL-TGEAGFHSVKTECGATYAEKLKQLQQEKMESGESGSGWMMNRVADGSK 632

Query: 611 YYYNTDSKEGSWV 623
           ++YN  +++ +W 
Sbjct: 633 FFYNAHTQQYAWA 671

 Score = 50.1 bits (118), Expect = 6e-06,   Method: Compositional matrix adjust.
 Identities = 48/177 (27%), Positives = 78/177 (44%), Gaps = 25/177 (14%)
 Frame = +3

Query: 282 RDAYEELLTQAEIQSNISTVN--------RMAAVDHINAVLQEGDPENTLLALKKPEAQL 333
           R A   LLT A+I   I TV+        R+ A++ IN  + +GD   TL +L+ P A+L
Sbjct: 75  RRAQNPLLTHADIVDTIETVHQKVQEEQERIKAIESINEAIDKGDESETLASLQMPSAKL 254

Query: 334 PAVYPFAAVMYQNELFNLQ------KQNTSNYLAHEELLIAVE-----------MLSAVA 376
             + P  AV YQ  L   +       Q+    L  EE+   V+           M   + 
Sbjct: 255 SNIDPLQAVHYQVLLAKEKDRKAEKTQDEGAVLWLEEIQSTVDHANRNAEEGLKMSRGIQ 434

Query: 377 LLNQALESSDLVAVQNQLRSPTIGFNNLDEAHVDRYADALLSVKQEALSQGQDTLSW 433
            +N+AL + D  ++   L +   GF+++       YA+ L  ++QE +  G+    W
Sbjct: 435 AVNEALATDDTDSLVAGL-TGEAGFHSVKTECGATYAEKLKQLQQEKMESGESGSGW 602

 Score = 34.3 bits (77), Expect = 0.41,   Method: Compositional matrix adjust.
 Identities = 36/146 (24%), Positives = 59/146 (40%), Gaps = 8/146 (5%)
 Frame = +3

Query: 217 AVIAINEAIEKGVAKQTIITLRNPNAVLTCVDDSLSQEYQXXXXXXXXXXXXXXXXXNSC 276
           A+ +INEAI+KG   +T+ +L+ P+A L+ +D   +  YQ                  + 
Sbjct: 171 AIESINEAIDKGDESETLASLQMPSAKLSNIDPLQAVHYQVLLAKEKDRKAEKTQDEGAV 350

Query: 277 ISEEERDAYEELLTQAEIQSNISTVNRMA--------AVDHINAVLQEGDPENTLLALKK 328
           +  E            EIQS +   NR A         +  +N  L   D  ++L+A   
Sbjct: 351 LWLE------------EIQSTVDHANRNAEEGLKMSRGIQAVNEALATDDT-DSLVAGLT 491

Query: 329 PEAQLPAVYPFAAVMYQNELFNLQKQ 354
            EA   +V       Y  +L  LQ++
Sbjct: 492 GEAGFHSVKTECGATYAEKLKQLQQE 569
>17703
          Length = 542

 Score = 56.2 bits (134), Expect = 9e-08,   Method: Compositional matrix adjust.
 Identities = 30/58 (51%), Positives = 46/58 (79%)
 Frame = +3

Query: 1396 ILNEIAKDIRNQRIHRKLRKAELSKLQQTLNALNKKAAFYEDQINYYDTYIETCVDNL 1453
            ++N I +DIRNQR +R  RK EL +++  LN+LN+K +FYE QI++Y+ Y++TC+DNL
Sbjct: 3    LINAIVQDIRNQRRYRNNRKQELLRVRNXLNSLNEKRSFYESQIDFYNQYVKTCLDNL 176
>11801
          Length = 743

 Score = 32.3 bits (72), Expect = 1.6,   Method: Composition-based stats.
 Identities = 13/33 (39%), Positives = 18/33 (54%)
 Frame = -1

Query: 722 DSVVKIQSWFRMVTARKSYLSRLRYFEDHKNEI 754
           D  +K+   +    A+ SYL   RYF+DHK  I
Sbjct: 164 DQFIKLDPQYDYRVAKYSYLQSYRYFDDHKQHI 66
>06426
          Length = 1132

 Score = 30.8 bits (68), Expect = 3.7,   Method: Compositional matrix adjust.
 Identities = 36/137 (26%), Positives = 55/137 (40%), Gaps = 6/137 (4%)
 Frame = +2

Query: 978  QNTLRQLLAPVVKEIIEDKALVINTNPVEVYKAWVNQLETQTGEASKLPYDVTTEQALTY 1037
            +N L     P+++  I D  +V  +       AW N+L    G  S        E  L Y
Sbjct: 170  RNGLXSSFGPIIEPFIMDDCVVPKSQLEMARDAWGNELPAMLGGTS-------FEGLLMY 328

Query: 1038 PEVKNKLEASIENLRKVTDKVLGSIISSLDLLPYGLRYI---AKVLKNS---IREKFPDA 1091
            P VK   + S+++L          ++  L ++P+ LR +    K L NS   I+  F D 
Sbjct: 329  PSVKANJK-SLDSL----------MLDPLQMIPHELRALNTDEKNLXNSHKMIKLYFGDE 475

Query: 1092 TEEELLKIVGNLLYYRY 1108
            T       +  L YY Y
Sbjct: 476  TPSS-THFMKMLDYYSY 523
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31981799|ref|NP_663477.2| ER lipid raft associated 1
[Mus musculus]
         (346 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

32005                                                                 176   6e-92
11691                                                                  29   2.9  
00382                                                                  28   3.6  
>32005
          Length = 1092

 Score =  176 bits (446), Expect(4) = 6e-92,   Method: Compositional matrix adjust.
 Identities = 81/102 (79%), Positives = 92/102 (90%)
 Frame = +3

Query: 80  GGVMIYIDRIEVVNMLAPYAVFDIVRNYTADYDKTLIFNKIHHELNQFCSAHTLQEVYIE 139
           GGV+IY +RIEVVN L   AVFDIV+NYTADYD+TLI+NKIHHELNQFCS H LQEVYI+
Sbjct: 96  GGVIIYFERIEVVNKLDTSAVFDIVKNYTADYDRTLIYNKIHHELNQFCSIHNLQEVYID 275

Query: 140 LFDQIDENLKQALQKDLNTMAPGLTIQAVRVTKPKIPEAIRR 181
           LFDQIDENL+QALQ+DL  +APGLT+QAVRVTKPKIPE IR+
Sbjct: 276 LFDQIDENLRQALQQDLYQLAPGLTVQAVRVTKPKIPEQIRK 401

 Score =  101 bits (252), Expect(4) = 6e-92,   Method: Compositional matrix adjust.
 Identities = 55/78 (70%), Positives = 66/78 (84%), Gaps = 2/78 (2%)
 Frame = +1

Query: 176 PEAIRR--NFELMEAEKTKLLIAAQKQKVVEKEAETERKRAVIEAEKIAQVAKIRFQQKV 233
           P ++ R  N+E ME EKTKLLI+ QKQKVVEKEAETERK+AVIEAEK AQVAKI +QQK+
Sbjct: 376 PRSLNRSANYEAMEGEKTKLLISIQKQKVVEKEAETERKKAVIEAEKQAQVAKITWQQKI 555

Query: 234 MEKETEKRISEIEDAAFL 251
           MEKE+E++I+EIED   L
Sbjct: 556 MEKESEQKIAEIEDLTHL 609

 Score = 65.9 bits (159), Expect(4) = 6e-92,   Method: Compositional matrix adjust.
 Identities = 28/33 (84%), Positives = 31/33 (93%)
 Frame = +2

Query: 49 YHIMLPSITTFRSVQTTLQTDEVKNVPCGTSGG 81
          YH MLP +T++RSVQTTLQTDEVKNVPCGTSGG
Sbjct: 2  YHFMLPVLTSYRSVQTTLQTDEVKNVPCGTSGG 100

 Score = 54.3 bits (129), Expect(4) = 6e-92,   Method: Compositional matrix adjust.
 Identities = 21/37 (56%), Positives = 31/37 (83%)
 Frame = +3

Query: 271 SNKHKLTPEYLELKKYQAIASNSKIYFGSNIPSMFVD 307
           +NK KLT E++E  KYQA+A+N+KI+FG+ IP +F+D
Sbjct: 666 ANKMKLTKEFVEFSKYQALAANTKIFFGNQIPDIFID 776
>11691
          Length = 472

 Score = 28.9 bits (63), Expect = 2.9,   Method: Compositional matrix adjust.
 Identities = 11/28 (39%), Positives = 20/28 (71%)
 Frame = -3

Query: 61  SVQTTLQTDEVKNVPCGTSGGVMIYIDR 88
           S+   L+T +V ++  G SGG++IY++R
Sbjct: 401 SIYFDLRTQKVSDIYSGGSGGILIYLNR 318
>00382
          Length = 808

 Score = 28.5 bits (62), Expect = 3.6,   Method: Compositional matrix adjust.
 Identities = 20/75 (26%), Positives = 32/75 (42%), Gaps = 3/75 (4%)
 Frame = -3

Query: 107 YTADYDKTLIFNKIHHELNQF---CSAHTLQEVYIELFDQIDENLKQALQKDLNTMAPGL 163
           Y+      ++F+ + H L +    C  H LQE          E LKQ L+KD +     L
Sbjct: 206 YSHQQASAIVFSPVRHMLTKLPLTCYPHCLQECV--------ERLKQTLEKDASRPLVAL 51

Query: 164 TIQAVRVTKPKIPEA 178
           T +  +   P++  A
Sbjct: 50  TREKGKTQTPQVDRA 6
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|60687506|ref|NP_033787.2| aldolase C,
fructose-bisphosphate [Mus musculus]
         (363 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

12684                                                                 207   6e-92
32571                                                                 189   3e-62
04687                                                                 104   6e-23
01154                                                                  83   2e-16
19270                                                                  50   1e-06
>12684
          Length = 1376

 Score =  207 bits (527), Expect(2) = 6e-92,   Method: Compositional matrix adjust.
 Identities = 96/119 (80%), Positives = 106/119 (89%)
 Frame = +1

Query: 122 ETTTQGLDGLLERCAQYKKDGADFAKWRCVLKISDRTPSALAILENANVLARYASICQQN 181
           E+TTQGLDGL ERCAQYKKDGA FAKWRCVLKIS  TPS  A++ENANVLARYASICQQN
Sbjct: 10  ESTTQGLDGLSERCAQYKKDGAQFAKWRCVLKISKNTPSHQAMMENANVLARYASICQQN 189

Query: 182 GIVPIVEPEILPDGDHDLKRCQYVTEKVLAAVYKALSDHHVYLEGTLLKPNMVTPGHAC 240
           G+VPIVEPE+LPDG+HDL+  Q VTE+VLA  YKALS+HHVYLEG+LLKPNMVT G AC
Sbjct: 190 GLVPIVEPEVLPDGEHDLETAQKVTEQVLAYTYKALSEHHVYLEGSLLKPNMVTAGQAC 366

 Score =  148 bits (373), Expect(2) = 6e-92,   Method: Compositional matrix adjust.
 Identities = 73/121 (60%), Positives = 89/121 (73%)
 Frame = +2

Query: 243 KYSPEEIAMATVTALRRTVPPAVPGVTFLSGGQSEEEASLNLNAINRCPLPRPWALTFSY 302
           K S E+IA+ATVTAL R VP AVPG+ FLSGGQSEE+A++NL+AIN+     PWALTFSY
Sbjct: 371 KVSHEQIAIATVTALSRXVPGAVPGICFLSGGQSEEDATINLDAINKYKGKNPWALTFSY 550

Query: 303 GRALQASALNAWRGQRDNAGAATEEFIKRAEMNGLAAQGRYEGSGDGGAAAQSLYIANHA 362
           GRALQAS L AW+G + N  AA  E +KRA+ NG A  G+Y G   G A  +SL++A HA
Sbjct: 551 GRALQASVLKAWKGNKANTDAAQGELLKRAKANGEACVGKYAGGVKGTAGGESLFVAGHA 730

Query: 363 Y 363
           Y
Sbjct: 731 Y 733
>32571
          Length = 515

 Score =  189 bits (481), Expect(2) = 3e-62,   Method: Compositional matrix adjust.
 Identities = 89/115 (77%), Positives = 100/115 (86%)
 Frame = -1

Query: 93  PFVRTIQDKGILVGIKVDKGVVPLAGTDGETTTQGLDGLLERCAQYKKDGADFAKWRCVL 152
           PFV  +++KGI+ GIKVDKGVVPLAG+  E TTQGLDGL ERCAQYKKDGA FAKWRCVL
Sbjct: 512 PFVDILKEKGIIPGIKVDKGVVPLAGSHNECTTQGLDGLSERCAQYKKDGAQFAKWRCVL 333

Query: 153 KISDRTPSALAILENANVLARYASICQQNGIVPIVEPEILPDGDHDLKRCQYVTE 207
           KIS  TPS  A++ENANVLARYASICQQNG+VPIVEPE+LPDG+HDL+  Q VTE
Sbjct: 332 KISKNTPSYQAMMENANVLARYASICQQNGLVPIVEPEVLPDGEHDLQTAQKVTE 168

 Score = 67.4 bits (163), Expect(2) = 3e-62,   Method: Compositional matrix adjust.
 Identities = 31/44 (70%), Positives = 37/44 (84%)
 Frame = -2

Query: 208 KVLAAVYKALSDHHVYLEGTLLKPNMVTPGHACPIKYSPEEIAM 251
           +VLA  YKAL+DHHV+LEGTLLKPNMVT G +C  KYS E+IA+
Sbjct: 166 QVLAFQYKALADHHVFLEGTLLKPNMVTAGQSCATKYSHEQIAV 35
>04687
          Length = 1330

 Score =  104 bits (259), Expect = 6e-23,   Method: Compositional matrix adjust.
 Identities = 53/96 (55%), Positives = 69/96 (71%)
 Frame = +2

Query: 268 VTFLSGGQSEEEASLNLNAINRCPLPRPWALTFSYGRALQASALNAWRGQRDNAGAATEE 327
           +TFLSGGQSEE+A++NL+AIN+     PWA+TFSYGRALQAS L AW+G+++N  AA  E
Sbjct: 2   ITFLSGGQSEEDATINLDAINKYKGKNPWAVTFSYGRALQASVLAAWKGKKENVAAAQAE 181

Query: 328 FIKRAEMNGLAAQGRYEGSGDGGAAAQSLYIANHAY 363
            + R + N  A  G+Y G   G A  QSL++A HAY
Sbjct: 182 LLARGKANSEACVGKYAGGVQGAAGGQSLFVAGHAY 289
>01154
          Length = 2463

 Score = 82.8 bits (203), Expect = 2e-16,   Method: Compositional matrix adjust.
 Identities = 40/69 (57%), Positives = 48/69 (69%)
 Frame = -2

Query: 295  PWALTFSYGRALQASALNAWRGQRDNAGAATEEFIKRAEMNGLAAQGRYEGSGDGGAAAQ 354
            PWALTFSYGRALQAS L AW+G + N  AA  E +KRA+ NG A  G+Y G   G A  +
Sbjct: 2462 PWALTFSYGRALQASVLKAWKGNKANTDAAQGELLKRAKANGEACVGKYAGGVKGTAGGE 2283

Query: 355  SLYIANHAY 363
            SL++A HAY
Sbjct: 2282 SLFVAGHAY 2256
>19270
          Length = 442

 Score = 50.1 bits (118), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 23/45 (51%), Positives = 32/45 (71%)
 Frame = -1

Query: 162 LAILENANVLARYASICQQNGIVPIVEPEILPDGDHDLKRCQYVT 206
           +  L+N++V   +     QNG+VPIVEPE+LPDG+HDL+  Q VT
Sbjct: 124 ICALDNSHVCMTFV----QNGLVPIVEPEVLPDGEHDLQTAQKVT 2
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|22203755|ref|NP_666312.1| eukaryotic translation
initiation factor 3, subunit C [Mus musculus]
         (911 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

08941                                                                 334   9e-92
33466                                                                 255   6e-68
05453                                                                 146   4e-35
00147                                                                  42   8e-04
28565                                                                  35   0.16 
38242                                                                  30   4.7  
>08941
          Length = 1327

 Score =  334 bits (857), Expect = 9e-92,   Method: Compositional matrix adjust.
 Identities = 158/216 (73%), Positives = 184/216 (85%)
 Frame = +2

Query: 669 VPFHLHINLELLECVYLVSAMLLEIPYMAAHESDARRRMISKQFHHQLRVGERQPLLGPP 728
           +P+H+HINLELLECVYLVSAMLLEIPYMAAHE D RRRMISK FHH +++ ERQ L GPP
Sbjct: 152 LPYHMHINLELLECVYLVSAMLLEIPYMAAHELDVRRRMISKNFHHVMKMSERQTLTGPP 331

Query: 729 ESMREHVVAASKAMKMGDWKTCHSFIINEKMNGKVWDLFPEADKVRTMLVRKIQEESLRT 788
           ESMREHVVAASKAMK G+W+ C +FIIN+KMN KVWDLF + DKVR ++  KIQEESLRT
Sbjct: 332 ESMREHVVAASKAMKAGNWRACKTFIINDKMNAKVWDLFFQRDKVRDLISSKIQEESLRT 511

Query: 789 YLFTYSSVYDSISMETLSDMFELDLPTVHSIISKMIINEELMASLDQPTQTVVMHRTEPT 848
           YLF YSSVYDS+S+  L+DMFEL+ P VHSIISKMIINEELMAS+D+PTQ + MHRTEPT
Sbjct: 512 YLFCYSSVYDSLSLPLLADMFELERPVVHSIISKMIINEELMASMDEPTQILSMHRTEPT 691

Query: 849 AQQNLALQLAEKLGSLVENNERVFDHKQGTYGGYFR 884
             Q+LALQLAEK+ S VENNER+ + KQG +  YF+
Sbjct: 692 RLQSLALQLAEKVASHVENNERIMEVKQGNF--YFQ 793
>33466
          Length = 612

 Score =  255 bits (651), Expect = 6e-68,   Method: Compositional matrix adjust.
 Identities = 121/200 (60%), Positives = 152/200 (76%)
 Frame = -3

Query: 442 ILTLVERMDEEFTKIMQNTDPHSQEYVEHLKDEAQVCAIIERVQRYLEEKGTTEEICQIY 501
           ILT++ER+DEEFTK++Q  D HS E+V+ LKDE +VC +++ +Q Y+E+ GT EEIC+ Y
Sbjct: 610 ILTVMERLDEEFTKMLQACDAHSTEFVDRLKDEQRVCGLLDTLQAYMEKIGTNEEICRAY 431

Query: 502 LRRILHTYYKFDYKAHQRQLTPPEGSSKSEQDQAENEGEDSAVLMERLCKYIYAKDRTDR 561
           LRRI H Y+KFD  A   ++   + +S+               LM++LCKYIYAKD TDR
Sbjct: 430 LRRIEHVYFKFDQTAFDEKVDKTKVTSEQ--------------LMDKLCKYIYAKDCTDR 293

Query: 562 IRTCAILCHIYHHALHSRWYQARDLMLMSHLQDNIQHADPPVQILYNRTMVQLGICAFRQ 621
           +RT AILC IY HALH RW++ARDLMLMSHLQDNIQH+D P QILYNRT+VQLG+CAFRQ
Sbjct: 292 LRTRAILCQIYXHALHDRWFKARDLMLMSHLQDNIQHSDVPTQILYNRTLVQLGLCAFRQ 113

Query: 622 GLTKDAHNALLDIQSSGRAK 641
           G  +DAHNAL+DIQSS RAK
Sbjct: 112 GHVRDAHNALVDIQSSNRAK 53
>05453
          Length = 1135

 Score =  146 bits (368), Expect = 4e-35,   Method: Compositional matrix adjust.
 Identities = 74/160 (46%), Positives = 100/160 (62%)
 Frame = +2

Query: 1   MSRFFTTXXXXXXXXXXXXXXXVTKPVSGNYGKQPLLLSEDEEDTKRVVRSAKDKRFEEL 60
           MSRFF                   +P   N  K    LS+DEEDT+RVVRS KDKR+++L
Sbjct: 374 MSRFFQAGSDSETESESEEEVQTQRPAVHN--KAAYQLSDDEEDTRRVVRSEKDKRYDDL 547

Query: 61  TNLIRTIRNAMKIRDVTKCLEEFELLGKAYGKAKSIVDKEGVPRFYIRILADLEDYLNEL 120
            N+I+T+RN  KI+D+   L +FE L K+Y KAK +VD+EG+PRFY+R L +L D++NE 
Sbjct: 548 RNIIKTMRNHKKIKDMASVLTDFEGLCKSYDKAKKVVDREGIPRFYLRCLVELLDFVNEC 727

Query: 121 WEDKEGXXXXXXXXXXXLSTLRQKIRKYNRDFESHITNYK 160
           WED+E            L+TLRQK+RKY RDFE+ +  Y+
Sbjct: 728 WEDREWRDTISKNNARGLTTLRQKLRKYCRDFETDLAKYR 847
>00147
          Length = 832

 Score = 42.4 bits (98), Expect = 8e-04,   Method: Composition-based stats.
 Identities = 16/28 (57%), Positives = 24/28 (85%)
 Frame = -3

Query: 138 LSTLRQKIRKYNRDFESHITNYKQNPEQ 165
           L+TLRQK+RKY RDFE+ +  Y++NP++
Sbjct: 89  LTTLRQKLRKYCRDFETDLAKYRENPDE 6
>28565
          Length = 712

 Score = 34.7 bits (78), Expect = 0.16,   Method: Composition-based stats.
 Identities = 14/23 (60%), Positives = 19/23 (82%)
 Frame = +1

Query: 138 LSTLRQKIRKYNRDFESHITNYK 160
           L+TLRQK+RKY RDFE+ +  Y+
Sbjct: 118 LTTLRQKLRKYCRDFETDLAKYR 186
>38242
          Length = 414

 Score = 30.0 bits (66), Expect = 4.7,   Method: Compositional matrix adjust.
 Identities = 24/93 (25%), Positives = 42/93 (45%), Gaps = 4/93 (4%)
 Frame = +3

Query: 481 IERVQRYLEEKGTTEEICQIYLRRILHTYYKFDYKAHQRQLTPPEGSSKSEQDQAENEGE 540
            E++ +  +  G ++E  Q ++  +  T       A   Q    EG     Q QAE +GE
Sbjct: 93  FEKLSQAADTAGDSQEAQQNFMDTLTQTMAGMTQNADGIQEETLEG-----QGQAEGQGE 257

Query: 541 DSAVLMERLCKYIYAKDR----TDRIRTCAILC 569
           +   +M+ L + + +K R    T+R R C + C
Sbjct: 258 EFMPMMQELMQTLLSKKRPLPLTERDR-CQVPC 353
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|46559406|ref|NP_796300.1| p21-activated kinase 2 [Mus
musculus]
         (524 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

14420                                                                 333   9e-92
12721                                                                 301   6e-82
13212                                                                 175   5e-44
18921                                                                 167   8e-42
19094                                                                 115   1e-40
00300                                                                 143   1e-34
28066                                                                 129   4e-30
13592                                                                 127   1e-29
14646                                                                 114   3e-28
01707                                                                 115   5e-26
01060                                                                 106   3e-23
14126                                                                 104   1e-22
09606                                                                 100   2e-21
37602                                                                  85   8e-21
03240                                                                  95   8e-20
15910                                                                  93   2e-19
00392                                                                  93   3e-19
01718                                                                  92   4e-19
30755                                                                  91   9e-19
18484                                                                  90   2e-18
31885                                                                  83   2e-16
06405                                                                  82   5e-16
01756                                                                  80   2e-15
04852                                                                  78   7e-15
02638                                                                  78   8e-15
13066                                                                  78   1e-14
29581                                                                  77   2e-14
21433                                                                  74   2e-13
01392                                                                  72   8e-13
04591                                                                  71   1e-12
01966                                                                  71   1e-12
19761                                                                  70   2e-12
27546                                                                  70   2e-12
21808                                                                  70   2e-12
19301                                                                  69   3e-12
11780                                                                  69   3e-12
09007                                                                  67   1e-11
21079                                                                  66   1e-11
00715                                                                  67   2e-11
12786                                                                  66   4e-11
17975                                                                  65   5e-11
26560                                                                  65   8e-11
07940                                                                  64   1e-10
14116                                                                  62   4e-10
25019                                                                  62   5e-10
26711                                                                  61   9e-10
04138                                                                  60   2e-09
27405                                                                  59   6e-09
07836                                                                  57   1e-08
18663                                                                  57   2e-08
21210                                                                  56   4e-08
07291                                                                  56   4e-08
03508                                                                  55   7e-08
29011                                                                  55   8e-08
28638                                                                  55   1e-07
00486                                                                  54   2e-07
12672                                                                  53   3e-07
14477                                                                  51   1e-06
11185                                                                  50   2e-06
17253                                                                  50   3e-06
20152                                                                  49   4e-06
17300                                                                  49   5e-06
32000                                                                  49   5e-06
28157                                                                  49   5e-06
27274                                                                  47   2e-05
16708                                                                  46   3e-05
20559                                                                  46   5e-05
06358                                                                  45   5e-05
32957                                                                  45   8e-05
01106                                                                  44   1e-04
20640                                                                  44   1e-04
32691                                                                  44   2e-04
00394                                                                  44   2e-04
31789                                                                  43   4e-04
36481                                                                  41   0.001
07833                                                                  41   0.001
26009                                                                  40   0.002
18996                                                                  40   0.003
29590                                                                  39   0.004
31489                                                                  39   0.006
18481                                                                  38   0.008
17516                                                                  38   0.010
16350                                                                  37   0.013
20513                                                                  37   0.017
18401                                                                  35   0.076
14104                                                                  33   0.22 
23319                                                                  33   0.23 
11404                                                                  33   0.27 
03294                                                                  33   0.29 
17637                                                                  32   0.51 
21800                                                                  31   1.0  
37063                                                                  31   1.1  
13305                                                                  31   1.2  
31120                                                                  30   2.3  
22005                                                                  30   3.1  
01970                                                                  28   8.0  
28068                                                                  28   8.9  
>14420
          Length = 528

 Score =  333 bits (854), Expect = 9e-92,   Method: Compositional matrix adjust.
 Identities = 153/175 (87%), Positives = 167/175 (95%)
 Frame = +2

Query: 278 KQINLQKQPKKELIINEILVMKELKNPNIVNFLDSYLVGDELFVVMEYLAGGSLTDVVTE 337
           K +NL +QPKKELIINEILVM+E +NPNIVN+LDSYLVG+EL+VVME+LAGGSLTDVVTE
Sbjct: 2   KTMNLSQQPKKELIINEILVMRENQNPNIVNYLDSYLVGEELWVVMEFLAGGSLTDVVTE 181

Query: 338 TCMDEAQIAAVCRECLQALEFLHANQVIHRDIKSDNVLLGMEGSVKLTDFGFCAQITPEQ 397
           TCMDE QIAAVCRECLQALEFLH NQVIHRDIKSDN+LLGM+GSVKLTDFGFCAQ++PEQ
Sbjct: 182 TCMDEGQIAAVCRECLQALEFLHENQVIHRDIKSDNILLGMDGSVKLTDFGFCAQLSPEQ 361

Query: 398 SKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRAL 452
           SKRSTMVGTPYWMAPEVVTRK YGP VDIWSLG+M IEM+EGEPPYLNENPLRAL
Sbjct: 362 SKRSTMVGTPYWMAPEVVTRKQYGPTVDIWSLGVMCIEMIEGEPPYLNENPLRAL 526
>12721
          Length = 821

 Score =  301 bits (770), Expect = 6e-82,   Method: Compositional matrix adjust.
 Identities = 138/265 (52%), Positives = 196/265 (73%)
 Frame = +1

Query: 227 MTDEEIMEKLRTIVSIGDPKKKYTRYEKIGQGASGTVFTATDVALGQEVAIKQINLQKQP 286
           ++ E+    L+ +V+ GDP+     + KIG+G++G V  AT    G+++A+K+++L+KQ 
Sbjct: 28  LSHEQFRAALQMVVTPGDPRTFLDDFMKIGEGSTGIVCIATSRD-GRQMAVKKMDLRKQQ 204

Query: 287 KKELIINEILVMKELKNPNIVNFLDSYLVGDELFVVMEYLAGGSLTDVVTETCMDEAQIA 346
           ++EL+ NE++VM++  +PNIV   +SYLV DEL+VVME++ GG+LTD+VT   MDE QIA
Sbjct: 205 RRELLFNEVVVMRDYHHPNIVEMYNSYLVNDELWVVMEFMEGGALTDIVTNNRMDEVQIA 384

Query: 347 AVCRECLQALEFLHANQVIHRDIKSDNVLLGMEGSVKLTDFGFCAQITPEQSKRSTMVGT 406
            VCR CL+AL FLHAN VIHRDIKSD++LL  +G VKL DFGFCAQ+T +  KR ++VGT
Sbjct: 385 TVCRACLKALAFLHANGVIHRDIKSDSILLSHDGKVKLXDFGFCAQVTQDLQKRKSLVGT 564

Query: 407 PYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQNP 466
           PYWMAPEV++R  YGP+VDIWSLGIM +EM++ EPP+ NE PL+A+  I     P+L+N 
Sbjct: 565 PYWMAPEVISRLPYGPEVDIWSLGIMVMEMIDAEPPFFNEPPLQAMRRIRDMPPPKLRNT 744

Query: 467 EKLSPIFRDFLNRCLEMDVEKRGSA 491
            K+SP  + F++R L  D  +R +A
Sbjct: 745 HKISPRLQGFIDRMLVRDPHQRATA 819
>13212
          Length = 1067

 Score =  175 bits (443), Expect = 5e-44,   Method: Compositional matrix adjust.
 Identities = 93/205 (45%), Positives = 124/205 (60%), Gaps = 9/205 (4%)
 Frame = -1

Query: 322  VMEYLAGGSLTDVVT--ETCMDEAQIAAVCRECLQALEFLHANQVIHRDIKSDNVLLGME 379
            V   L  G+L  ++   E  M EAQI  VC E   AL+FLH + VIHRDIK+ NVLL ++
Sbjct: 1049 VFRVLWWGALDSIMVDLEKPMTEAQICYVCHEMCMALDFLHRHHVIHRDIKAGNVLLTID 870

Query: 380  GSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKA-----YGPKVDIWSLGIMAI 434
            G VKL DFG  A+ T  Q KR T +GTPYWMAPEVV  +      Y  K DIWSLG+  I
Sbjct: 869  GEVKLADFGVSAKNTQTQQKRDTFIGTPYWMAPEVVLCETLKDTPYDFKADIWSLGVTLI 690

Query: 435  EMVEGEPPYLNENPLRALYLIATNGTPELQNPEKLSPIFRDFLNRCLEMDVEKRGSAKEL 494
            E  + EPP    +P+R L  I  +  P L+ P+K + +F+DF+ +CL  D   R +A EL
Sbjct: 689  EFAQIEPPNKEMHPMRVLIKIHKSDPPTLEKPKKWTKLFKDFIAKCLVKDPNLRPTAAEL 510

Query: 495  LQHPFLKLAKPL--SSLTPLILAAK 517
            L+HPF+K A     +++  LI+ +K
Sbjct: 509  LEHPFMKRATATDKAAICDLIMESK 435
>18921
          Length = 697

 Score =  167 bits (424), Expect = 8e-42,   Method: Compositional matrix adjust.
 Identities = 83/198 (41%), Positives = 124/198 (62%), Gaps = 2/198 (1%)
 Frame = +2

Query: 254 KIGQGASGTVFTATDVALGQEVAIKQINLQKQPKKELIINEILVMKELKNPNIVNFLDSY 313
           K+G+G+ G+VF +     GQ +AIKQ+ +    ++  II EI +M++  +  IV +  SY
Sbjct: 50  KLGEGSYGSVFKSLHKETGQVLAIKQVPVDTDLQE--IIKEISIMQQCDSKYIVKYYGSY 223

Query: 314 LVGDELFVVMEYLAGGSLTDV--VTETCMDEAQIAAVCRECLQALEFLHANQVIHRDIKS 371
               +L++VMEY   GS++D+  +    + E +IA +    L+ L +LH+ + IHRDIK+
Sbjct: 224 FKNTDLWIVMEYCGAGSVSDIMRLRNKTLVEREIATILYYTLKGLXYLHSRRKIHRDIKA 403

Query: 372 DNVLLGMEGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGI 431
            N+LL  EG  KL DFG   Q+T   +KR+T++GTPYWMAPEV+    Y    DIWSLGI
Sbjct: 404 GNILLNNEGHAKLADFGVAGQLTDTMAKRNTVIGTPYWMAPEVIQEIGYDCVADIWSLGI 583

Query: 432 MAIEMVEGEPPYLNENPL 449
            A+EM EG+PP +  + L
Sbjct: 584 TALEMAEGKPPVMETSIL 637
>19094
          Length = 898

 Score =  115 bits (289), Expect(2) = 1e-40,   Method: Compositional matrix adjust.
 Identities = 54/113 (47%), Positives = 74/113 (65%), Gaps = 2/113 (1%)
 Frame = +1

Query: 329 GSLTDV--VTETCMDEAQIAAVCRECLQALEFLHANQVIHRDIKSDNVLLGMEGSVKLTD 386
           GS++D+  +    + E +IA +    L+ L +LH+ + IHRDIK+ N+LL  EG  KL D
Sbjct: 10  GSVSDIMRLRNKTLVEREIATILYYTLKGL*YLHSRRKIHRDIKAGNILLNNEGHAKLAD 189

Query: 387 FGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEG 439
           FG   Q+T   +KR+T++GTPYWMAPEV+    Y    DIWSLGI A+EM EG
Sbjct: 190 FGVAGQLTDTMAKRNTVIGTPYWMAPEVIQEIGYDCVADIWSLGITALEMAEG 348

 Score = 69.3 bits (168), Expect(2) = 1e-40,   Method: Compositional matrix adjust.
 Identities = 33/80 (41%), Positives = 51/80 (63%)
 Frame = +3

Query: 439 GEPPYLNENPLRALYLIATNGTPELQNPEKLSPIFRDFLNRCLEMDVEKRGSAKELLQHP 498
           G+PPY + +P+RA+++I T   P  + P+K S  F DF+++CL  + E R +A +LLQH 
Sbjct: 345 GKPPYGDIHPMRAIFMIPTKPPPSFRQPDKWSTEFIDFVSKCLVKNPENRATAVDLLQHD 524

Query: 499 FLKLAKPLSSLTPLILAAKE 518
           F+K A+    L  +I  AKE
Sbjct: 525 FIKKAEACEILQAMIREAKE 584
>00300
          Length = 2318

 Score =  143 bits (361), Expect = 1e-34,   Method: Compositional matrix adjust.
 Identities = 84/264 (31%), Positives = 143/264 (54%), Gaps = 9/264 (3%)
 Frame = -1

Query: 248  KYTRYEKIGQGASGTVFTATDVALGQEVAIKQINLQKQPKKEL--IINEILVMKELKNPN 305
            ++ R  KIG+G  G V+TA +++ G+ +A+K++  Q    ++L  + +EI + + +++ N
Sbjct: 1655 RWQRGNKIGEGQFGKVYTAVNMSTGELMALKEMKFQPNDLQQLREMCDEIKIFEGIQHEN 1476

Query: 306  IVNFLDSYLVGDELFVVMEYLAGGSLTDVVTETCMDEAQIAAVCRECLQALEFLHANQVI 365
            +V +    +  DE+ + MEY   G++ +   +  + E  I    RE + A+  LH N ++
Sbjct: 1475 LVKYYGVEVHKDEMLMFMEYCDTGTIEEAA-KMGLPEYLIRRYTREIVLAVNHLHENSIV 1299

Query: 366  HRDIKSDNVLLGMEGSVKLTDFGFCAQITPEQS---KRSTMVGTPYWMAPEVVTRK---A 419
            HRDIK  N+ L   G VKL DFG   ++    +   +   +VGT  +MAPEV T+     
Sbjct: 1298 HRDIKGANIFLTSNGHVKLGDFGCSVKLKSHTTMPGEFHNLVGTTAYMAPEVFTQNDQGG 1119

Query: 420  YGPKVDIWSLGIMAIEMVEGEPPYLN-ENPLRALYLIATNGTPELQNPEKLSPIFRDFLN 478
            YG   DIWSLG + IEM  G+ P+ + +N  + +Y +     P +  P+ LS   + FL+
Sbjct: 1118 YGRAADIWSLGCVVIEMATGKRPWHDLDNNYQIMYKVGIGHKPAV--PDSLSVEGKHFLD 945

Query: 479  RCLEMDVEKRGSAKELLQHPFLKL 502
              +  D  +R  A +LL H F K+
Sbjct: 944  LIMCHDPAQRALASQLLDHTFTKV 873
>28066
          Length = 837

 Score =  129 bits (323), Expect = 4e-30,   Method: Compositional matrix adjust.
 Identities = 69/139 (49%), Positives = 88/139 (63%), Gaps = 11/139 (7%)
 Frame = +2

Query: 71  RPEISPPSDFEHTIHVGFDAVTGEFTGMPEQWARLLQTSNITKLEQKKNPQAVLDVLKFY 130
           +P ISPPS+FEHT+HVGFD +TGEFTGMPE WARLLQ++NI+K+EQK+NPQAVLDVL +Y
Sbjct: 371 KPVISPPSNFEHTVHVGFDPLTGEFTGMPESWARLLQSANISKMEQKQNPQAVLDVLNYY 550

Query: 131 DSNTVKQ---KYL-----SFTPPEKDGFPSGTPAL---NTKGSETSAVVTXXXXXXXXAA 179
           D+++ ++   KY+     S     K        AL   N    E +AV            
Sbjct: 551 DTSSKERRESKYMINIKPSSANSSKSNLSEKLSALVIINQNKPEQNAVAALGDGDNNEEP 730

Query: 180 PPVIAPRPDHTKSIYTRSV 198
            P IA RPD TKSIYT+ +
Sbjct: 731 RPSIAARPDKTKSIYTKPI 787
>13592
          Length = 980

 Score =  127 bits (319), Expect = 1e-29,   Method: Compositional matrix adjust.
 Identities = 85/263 (32%), Positives = 143/263 (54%), Gaps = 12/263 (4%)
 Frame = +2

Query: 254 KIGQGASGTVFTATDVALGQEVAIKQINLQKQPKKEL--IINEILVMKELKNPNIVNFLD 311
           KIGQG  G V+TA +   G+ +A+K+I +Q    + L  +  E+ +++ +K+ N+V +  
Sbjct: 5   KIGQGRFGKVYTAVNNNTGELMAMKEIAIQPGETRALKNVAEELKILEGIKHKNLVRYYG 184

Query: 312 SYLVGDELFVVMEYLAGGSLTDVVTETC-MDEAQIAAVCRECLQALEFLHANQVIHRDIK 370
             +  +EL + ME  + G+L  +V  T  + EA       + L  +  LH + ++HRDIK
Sbjct: 185 IEVHREELLIFMELCSEGTLESLVELTGGLPEALSRRFTAQLLSGVAELHKHGIVHRDIK 364

Query: 371 SDNVLLGMEGS--VKLTDFGFCAQITPEQS---KRSTMVGTPYWMAPEVVTR---KAYGP 422
           + N+ L ++GS  +KL DFG   +I    +   +    VGT  +MAPEV T+     +G 
Sbjct: 365 TANIFL-VDGSNSLKLGDFGSAVKIQAHTTVPGELQGYVGTQAYMAPEVFTKTNSDGHGR 541

Query: 423 KVDIWSLGIMAIEMVEGEPPYLN-ENPLRALYLIATNGTPELQNPEKLSPIFRDFLNRCL 481
             DIWS+G + +EM  G+ P+   ++  + ++ +     P  Q PE LS    DF++ CL
Sbjct: 542 LADIWSVGCVVVEMASGKRPWAQFDSNFQIMFKVGMGEKP--QAPESLSQEGHDFIDHCL 715

Query: 482 EMDVEKRGSAKELLQHPFLKLAK 504
           + D ++R SA ELL+  F K  +
Sbjct: 716 QHDPKQRLSAIELLEQNFCKSGR 784
>14646
          Length = 623

 Score =  114 bits (286), Expect(2) = 3e-28,   Method: Compositional matrix adjust.
 Identities = 66/141 (46%), Positives = 85/141 (60%), Gaps = 15/141 (10%)
 Frame = +2

Query: 71  RPEISPPSDFEHTIHVGFDAVTGEFTGMPEQWARLLQTSNITKLEQKKNPQAVLDVLKFY 130
           +P ISPPS+FEHT+HVGFD  TGEFTGMPE WA LLQ++NI+K EQK+NPQAVLDVL +Y
Sbjct: 143 KPVISPPSNFEHTVHVGFDPHTGEFTGMPESWANLLQSANISKTEQKQNPQAVLDVLNYY 322

Query: 131 DSNTVKQ---KYLSFTPP-----EKDGFPSGTPAL------NTKGSETSAVVTXXXXXXX 176
           D+++ ++   KY++   P      K        A+      N    +T            
Sbjct: 323 DTSSKERRGSKYMTNIKPSSGNSSKSNLSDKVSAMLVLSQQNKSEQQTLLGAGXGEGGRR 502

Query: 177 XAAPPV-IAPRPDHTKSIYTR 196
             +P   IA RPD TKSIYT+
Sbjct: 503 MKSPHSPIATRPDKTKSIYTK 565

 Score = 28.9 bits (63), Expect(2) = 3e-28,   Method: Compositional matrix adjust.
 Identities = 20/37 (54%), Positives = 22/37 (59%)
 Frame = +3

Query: 12 PAPPVRMSSTIFSTGGKDPLSANHSLKPLPSVPEEKK 48
          PAPPVR+ S   ST     LS  +  KPLP  PEEKK
Sbjct: 3  PAPPVRLESKREST-----LSQEY--KPLPREPEEKK 92
>01707
          Length = 757

 Score =  115 bits (287), Expect = 5e-26,   Method: Compositional matrix adjust.
 Identities = 68/216 (31%), Positives = 119/216 (55%), Gaps = 4/216 (1%)
 Frame = +1

Query: 244 DPKKKYTRYEKIGQGASGTVFTATDVALGQEVAIKQ-INLQKQPK-KELIINEILVMKEL 301
           D  +KY +  KIG+G+ G VF   +    Q VAIK+ +  +  P  K++ + EI ++K+L
Sbjct: 55  DRMEKYEKIGKIGEGSYGVVFKCRNKETSQLVAIKKFVESEDDPLIKKIAMREIRMLKQL 234

Query: 302 KNPNIVNFLDSYLVGDELFVVMEYLAGGSLTDVVTE-TCMDEAQIAAVCRECLQALEFLH 360
           K+PN+V  ++ +     L +V +Y+    L ++      + E  +  +  + L A+ F H
Sbjct: 235 KHPNLVRLIEVFRRKKRLHLVFDYVDHTLLNELDRYPRGLPEPMVKRIIYQTLLAVNFCH 414

Query: 361 ANQVIHRDIKSDNVLLGMEGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPE-VVTRKA 419
               IHRD+K +N+L+  +G VKL DFGF   +T    + +  V T ++ APE +V    
Sbjct: 415 QYNTIHRDVKPENILITRQGQVKLCDFGFARILTGPGDEYTDYVATRWYRAPELLVGDTQ 594

Query: 420 YGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLI 455
           YGP VD+W++G +  E++ G+  +   + +  L+LI
Sbjct: 595 YGPPVDVWAIGCVFAELLTGQALWPGRSDVDQLHLI 702
>01060
          Length = 1800

 Score =  106 bits (264), Expect = 3e-23,   Method: Compositional matrix adjust.
 Identities = 75/283 (26%), Positives = 132/283 (46%), Gaps = 32/283 (11%)
 Frame = +1

Query: 250 TRYEKIGQGASGTVFTATDVALGQEVAIKQINLQKQPKK--ELIINEILVMKELKNPNIV 307
           T ++KIG+G  G V+     A G+++A+K+I L+          I EI +++EL++ NIV
Sbjct: 82  TDFQKIGEGTYGVVYKCRHRATGRKLAMKKIRLRGSEDGVPSSAIREIAMLRELRHTNIV 261

Query: 308 NFLDSYLVGDELFVVMEYLAGG--SLTDVVTE-TCMDEAQIAAVCRECLQALEFLHANQV 364
              D  +  + LF+V E+L+       D   E   +D   + +   + +  + F H  ++
Sbjct: 262 CLEDVIMEDERLFLVFEFLSMDLKMYIDKFPEGVVLDRRLVKSYVFQIVTGIXFCHQRRI 441

Query: 365 IHRDIKSDNVLLGMEGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKA-YGPK 423
           +HRD+K  N+L+   G++K+ DFG            +  V T ++ APE++   + Y   
Sbjct: 442 VHRDLKPQNLLINHTGAIKIADFGMARTFALPVRAYTHEVVTLWYRAPEILMGASKYSTP 621

Query: 424 VDIWSLGIMAIEMVEGEPPYLNENPLRALYLI-------------------ATNGTPELQ 464
           VD+WS+G +  +M+   P +  ++ +  L+ I                   A NG   L 
Sbjct: 622 VDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIFRIIGTPTEQTWPEFHKLPAFNGMFPLW 801

Query: 465 NPEKLSPIFR-------DFLNRCLEMDVEKRGSAKELLQHPFL 500
              KLS           D + R L+ D  +R S K++LQH + 
Sbjct: 802 KEGKLSETLTDLDSLGLDLIERTLKCDPAQRISCKKMLQHAYF 930
>14126
          Length = 1265

 Score =  104 bits (259), Expect = 1e-22,   Method: Compositional matrix adjust.
 Identities = 89/296 (30%), Positives = 147/296 (49%), Gaps = 40/296 (13%)
 Frame = +3

Query: 246 KKKYTRYEKIGQGASGTVFTATDVA-LGQEVAIKQINLQKQPKKE--LIINEILVMKELK 302
           ++KY     IG GA GTV+ A D+   G+ VA+K+I L    +    + I EI ++K+L+
Sbjct: 186 EQKYEEVAVIGNGAYGTVYKARDLRNQGEFVAMKRIRLNNTEEGMPMMAIREISMLKQLE 365

Query: 303 ---NPNIVNFLD--SYLVGDE---LFVVMEYLAGGSLTDVVTETC----MDEAQIAAVCR 350
              +PN+V  LD     + D    L +V EY+     T +    C    +   +I  +  
Sbjct: 366 QYEHPNVVRLLDVSHNTITDREIRLNLVFEYIEHDLATYLAK--CPSPGLGPDRIKDLML 539

Query: 351 ECLQALEFLHANQVIHRDIKSDNVLLGMEGSVKLTDFGFCAQITPEQSKRSTMVGTPYWM 410
           + L  ++FLH+N+++HRD+K  N+L+  +G +KL DFG  A+I       +T+V T ++ 
Sbjct: 540 QLLNGVDFLHSNRIVHRDLKPQNLLISKDGRLKLADFGL-ARIYSFHMALTTVVVTLWYR 716

Query: 411 APEVVTRKAYGPKVDIWSLGIMAIEM---------------------VEGEPPYLNENPL 449
           +PEV+ +  YG  VDIWS G +  E+                     V G PP  +    
Sbjct: 717 SPEVLMQAEYGTSVDIWSCGCIFAELFTRRALFKGSSEFDQLKKIFEVIGLPPAGDWPEG 896

Query: 450 RALYLIATNGTP--ELQN--PEKLSPIFRDFLNRCLEMDVEKRGSAKELLQHPFLK 501
            +++  +   TP   LQ   PE + P  +D + + L     +R S++E L HP+L+
Sbjct: 897 VSVHRNSFRPTPPVPLQTLVPE-MDPQAKDLMEKMLVFKSGRRISSRESLLHPYLR 1061
>09606
          Length = 1300

 Score = 99.8 bits (247), Expect = 2e-21,   Method: Compositional matrix adjust.
 Identities = 78/305 (25%), Positives = 129/305 (42%), Gaps = 33/305 (10%)
 Frame = -3

Query: 247  KKYTRYEKIGQGASGTVFTATDVALGQEVAIKQINLQKQPKKELIINEILVMKELKNPNI 306
            + +  YE++G+G    ++          VAI  I   K+P+   + N + +  ++ +PN+
Sbjct: 1115 ENFVLYEELGKGEHSIIYKGRRKGTINFVAIHCIEKCKRPE---VTNTVRMTHDISHPNV 945

Query: 307  VNFLDSYLVGDELFVVMEYLAGGSLTDVVTE-TCMDEAQIAAVCRECLQALEFLHANQVI 365
            V F + Y   + L++V+E   GGSL D++ +   + E  I       +  L ++H+  ++
Sbjct: 944  VQFHEWYETSNHLWLVVELCTGGSLADILAQDHHLPETSIRDFGIHLVTGLHYIHSLGIL 765

Query: 366  HRDIKSDNVLLGMEGSVKLTDFGFCA----------------------QITPEQSKRSTM 403
              D++   VLL   G +K  DFG                         Q   E  K+   
Sbjct: 764  FHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEAGDQWNIQSAEEMMKQVPT 585

Query: 404  VGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPEL 463
             G+P +MAPEV          D+W+LG +  EM  G PP+L E      Y I  +     
Sbjct: 584  SGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFSGHPPFLGET-----YDITKDKVLNK 420

Query: 464  QNP----------EKLSPIFRDFLNRCLEMDVEKRGSAKELLQHPFLKLAKPLSSLTPLI 513
            + P           K SP F + L   L+ D  +R S   L++H F +    LSSL    
Sbjct: 419  EFPLPKVKGSRLSAKPSPEFLNLLESLLQKDSTRRLSWASLVKHAFWQ--GGLSSLVKEF 246

Query: 514  LAAKE 518
              ++E
Sbjct: 245  TMSEE 231
>37602
          Length = 804

 Score = 85.1 bits (209), Expect(3) = 8e-21,   Method: Compositional matrix adjust.
 Identities = 41/83 (49%), Positives = 53/83 (63%), Gaps = 1/83 (1%)
 Frame = -1

Query: 306 IVNFLDSYLVGDELFVVMEYLAGGSLTDVVTETC-MDEAQIAAVCRECLQALEFLHANQV 364
            V + DSYL  ++L++ MEY  GGS+ D+   T  + E QIA VCRE L+ L +LH    
Sbjct: 333 FVGYFDSYLRREKLWIAMEYCGGGSMQDIYHVTGPLTEPQIAFVCRETLKGLHYLHRRGK 154

Query: 365 IHRDIKSDNVLLGMEGSVKLTDF 387
           +HRDIK  N+LL  EG VKL DF
Sbjct: 153 MHRDIKGANILLTEEGDVKLADF 85

 Score = 28.1 bits (61), Expect(3) = 8e-21,   Method: Compositional matrix adjust.
 Identities = 12/29 (41%), Positives = 16/29 (55%)
 Frame = -2

Query: 379 EGSVKLTDFGFCAQITPEQSKRSTMVGTP 407
           +G+     FG  AQIT    KR + +GTP
Sbjct: 110 KGTSSWRTFGVSAQITATMCKRKSFIGTP 24

 Score = 25.4 bits (54), Expect(3) = 8e-21,   Method: Compositional matrix adjust.
 Identities = 14/32 (43%), Positives = 19/32 (59%)
 Frame = -3

Query: 276 AIKQINLQKQPKKELIINEILVMKELKNPNIV 307
           A K I L+      +I  EIL+MK+ K+PNI 
Sbjct: 424 AFKVIKLEPGDDFAIIQQEILMMKDCKHPNIC 329

 Score = 41.2 bits (95), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 16/28 (57%), Positives = 19/28 (67%)
 Frame = -1

Query: 386 DFGFCAQITPEQSKRSTMVGTPYWMAPE 413
           DFG  AQIT    KR + +GTPYWMA +
Sbjct: 744 DFGVSAQITATMCKRKSFIGTPYWMARK 661
>03240
          Length = 1683

 Score = 94.7 bits (234), Expect = 8e-20,   Method: Compositional matrix adjust.
 Identities = 71/256 (27%), Positives = 109/256 (42%), Gaps = 52/256 (20%)
 Frame = -3

Query: 252  YEKI---GQGASGTVFTATDVALGQEVAIKQINLQKQPKKELIIN---EILVMKELKNPN 305
            +EKI   G GA G V        G   A+K +      K+  + +   E  ++ E  N  
Sbjct: 1285 FEKIKTLGVGAFGEVSLCRKNDTGMLYAMKTLRKSDVLKRNQVAHVKAERDILAEADNEW 1106

Query: 306  IVNFLDSYLVGDELFVVMEYLAGGSLTDVVTET-CMDEAQIAAVCRECLQALEFLHANQV 364
            +V    S+   + L+ VM+Y+ GG L  ++     +DE        E +QA+E +H    
Sbjct: 1105 VVKLYYSFQDHNYLYFVMDYVPGGDLMGLLIRMEILDEPLARFYVAELVQAIESVHRMGF 926

Query: 365  IHRDIKSDNVLLGMEGSVKLTDFGFCAQ-------------------------------- 392
            IHRDIK DN+L+   G +KLTDFG C                                  
Sbjct: 925  IHRDIKPDNILIDRNGHIKLTDFGLCTGFRWTHNSKYYQRDGTHARQDSMEVKCQLDEQC 746

Query: 393  ----ITPEQSKR--------STMVGTPYWMAPEVVTR-KAYGPKVDIWSLGIMAIEMVEG 439
                + P + +R         ++VGTP ++APEV++R   Y    D WS+G++  EM+ G
Sbjct: 745  QCEILKPLERRRKREQRCLAHSLVGTPNYIAPEVLSRLGGYTSVCDWWSVGVILFEMLVG 566

Query: 440  EPPYLNENPLRALYLI 455
             PP+    P    Y +
Sbjct: 565  HPPFYANTPAETQYKV 518
>15910
          Length = 1361

 Score = 93.2 bits (230), Expect = 2e-19,   Method: Compositional matrix adjust.
 Identities = 57/173 (32%), Positives = 95/173 (54%), Gaps = 5/173 (2%)
 Frame = +2

Query: 334 VVTETCMDEAQIAAVCRECLQALEFLHANQVIHRDIKSDNVL---LGMEGSVKLTDFGFC 390
           +VT     E   A    + L  ++++HAN V+HRD+K +N+L   +  +  +KL DFG  
Sbjct: 437 IVTRGQYTEKDAARAISDILHGVQYIHANGVVHRDLKPENLLYECMTDDSKLKLADFGLS 616

Query: 391 AQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLR 450
             I PE  + ST+ GTP + APEV+    Y P VD+WS+G++A  ++ G  P+  EN   
Sbjct: 617 RIIEPE-VQMSTVCGTPGYCAPEVLKGDKYTPSVDMWSVGVIAYILLCGYEPFFAENEFE 793

Query: 451 ALYLIATNGTPEL--QNPEKLSPIFRDFLNRCLEMDVEKRGSAKELLQHPFLK 501
            +Y     G  +   +   ++S   +D + + L +D +KR +A E L+ P++K
Sbjct: 794 -MYRKIIKGEYKFDEEYWSEISENAKDVVRKLLVIDPKKRLTATEALRLPWVK 949
>00392
          Length = 668

 Score = 92.8 bits (229), Expect = 3e-19,   Method: Compositional matrix adjust.
 Identities = 63/195 (32%), Positives = 101/195 (51%), Gaps = 10/195 (5%)
 Frame = +3

Query: 297 VMKELKNPNIVNFLDSYLVGDE-----LFVVMEYLAGGSLTDVVTETCMDEAQIAA-VCR 350
           ++KEL++PNIV F D +   +      + +V E +  G+L   +        +I    CR
Sbjct: 90  MLKELQHPNIVRFFDYWEEHNHRNRKVIILVTELMTSGTLKTYLKRFKKPNVKILKNWCR 269

Query: 351 ECLQALEFLHANQ--VIHRDIKSDNVLL-GMEGSVKLTDFGFCAQITPEQSKRSTMVGTP 407
           + L+ L FLH     VIHRD+K DN+ + G  GSVK+ D G        QS   +++GTP
Sbjct: 270 QVLKGLYFLHTRTPPVIHRDLKCDNIFITGPTGSVKIGDLGLAT--LKNQSFAKSVIGTP 443

Query: 408 YWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGT-PELQNP 466
            +MAPE+   + Y   VD+++ G+  +EM   E PY   +    +Y   T+G  PE  + 
Sbjct: 444 EFMAPEMY-EEHYDEAVDVYAFGMCMLEMASSEYPYSECSNAAQIYKRVTSGVLPEALDK 620

Query: 467 EKLSPIFRDFLNRCL 481
             ++ I RD ++ C+
Sbjct: 621 VAITEI-RDIIHHCI 662
>01718
          Length = 959

 Score = 92.4 bits (228), Expect = 4e-19,   Method: Compositional matrix adjust.
 Identities = 69/256 (26%), Positives = 124/256 (48%), Gaps = 12/256 (4%)
 Frame = +3

Query: 253 EKIGQGASGTVFTATDVALGQEVAIKQINLQKQPKKELIINEILVMKELKNPNIVNFLDS 312
           EKIG G    VF  T    GQ +A+K   +     +  ++ E+ ++  L++ NI+ F+  
Sbjct: 165 EKIGAGFFSEVFKVTHRITGQVMALKMNTMTS--NRHNMLREVQLLNRLQHANILRFMGV 338

Query: 313 YLVGDELFVVMEYLAGGSLTDVVTETCMDE----AQIAAVCRECLQALEFLHANQVIHRD 368
            +   +L  + EY+  G+L  ++ +   DE     Q   +     + L++LH+ + IHRD
Sbjct: 339 CVHEGQLHALTEYIPSGNLEQLLEKK--DEELPWTQRIQLTLGLARGLDYLHSTRFIHRD 512

Query: 369 IKSDNVLLGMEGS----VKLTDFGFCAQI-TPEQSKRSTMVGTPYWMAPEVVTRKAYGPK 423
           + S N+L+  E +      + DFG   +I  P   ++   VG+PYWMAPEV+    Y  +
Sbjct: 513 LTSKNILIRREDNHGYHAVIADFGLATKIPDPLDKEKLPTVGSPYWMAPEVLNGHFYNER 692

Query: 424 VDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQNPEKLSPIFRDFLN---RC 480
            D++S+GI+  E+    P   +  P      +   G   +   E +S    D+L    +C
Sbjct: 693 ADLFSVGIIMCEITARIPADPDIMP-----RMNNFGVDYVALSEMISYCPLDYLQLAFKC 857

Query: 481 LEMDVEKRGSAKELLQ 496
            ++D +KR    E+++
Sbjct: 858 CQVDPQKRPRGVEIIE 905
>30755
          Length = 1137

 Score = 91.3 bits (225), Expect = 9e-19,   Method: Compositional matrix adjust.
 Identities = 51/169 (30%), Positives = 80/169 (47%), Gaps = 5/169 (2%)
 Frame = +2

Query: 337 ETCMDEAQIAAVCRECLQALEFLHANQVIHRDIKSDNVLLGMEGSVKLTDFGFCAQITPE 396
           E    E +      E + AL +LH+  +I+RD+K +N+LL  +G +K+ DFG C +    
Sbjct: 14  ERIFTEERTRFYGAEIISALGYLHSQGIIYRDLKLENLLLDKDGHIKVADFGLCKEDITY 193

Query: 397 QSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIA 456
                T  GTP ++APEV+    YG  VD W  G++  EM+ G  P+ N +      LI 
Sbjct: 194 GRTTKTFCGTPEYLAPEVLDDNDYGRAVDWWGTGVVMYEMICGRLPFYNRDHDVLFTLIL 373

Query: 457 TNGTPELQNPEKLSPIFRDFLNRCLEMDVEKR-----GSAKELLQHPFL 500
                +++ P  ++   +  L+  L  D   R        KE+  HPF 
Sbjct: 374 VE---DVKFPRNITDEAKSLLSGLLAKDPRNRLGGGQDDVKEIQAHPFF 511
>18484
          Length = 635

 Score = 90.1 bits (222), Expect = 2e-18,   Method: Compositional matrix adjust.
 Identities = 40/102 (39%), Positives = 59/102 (57%)
 Frame = +1

Query: 346 AAVCRECLQALEFLHANQVIHRDIKSDNVLLGMEGSVKLTDFGFCAQITPEQSKRSTMVG 405
           A    E    L FLH   +I+RD+K DNV+L  EG +K+ DFG C +     +   T  G
Sbjct: 52  AFYAAEIAVGLFFLHDQGIIYRDLKLDNVMLDSEGHIKIADFGMCKEGMTGDATTRTFCG 231

Query: 406 TPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNEN 447
           TP ++APE+V  + Y   VD W+ G++  EM+ G+PP+  E+
Sbjct: 232 TPDYIAPEIVLYQPYSKSVDWWAYGVLLFEMLAGQPPFDGED 357
>31885
          Length = 529

 Score = 83.2 bits (204), Expect = 2e-16,   Method: Compositional matrix adjust.
 Identities = 48/153 (31%), Positives = 80/153 (52%), Gaps = 6/153 (3%)
 Frame = -2

Query: 297 VMKELKNPNIVNFLDSYLVGDELFVVMEYLAGGSL-TDVVTETCMDEAQIAAVCRECLQA 355
           ++  L +P +VN   ++   ++LF+V++   GG L   +  E    E  +     +    
Sbjct: 513 MLTRLDHPFLVNLWYAFQDEEDLFMVVDLFLGGDLRYHMQQEVSFREDCVKFYLCQLALV 334

Query: 356 LEFLHANQVIHRDIKSDNVLLGMEGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVV 415
           L++L + +++HRDIK DN+LL  +G   +TDF    Q+  ++   ST    PY MAPEV 
Sbjct: 333 LDYLRSQKIVHRDIKPDNILLDEQGHCHVTDFNIATQLEDDELATSTSGTRPY-MAPEVY 157

Query: 416 -----TRKAYGPKVDIWSLGIMAIEMVEGEPPY 443
                 R+ YG  VD WSLG+   E+++   P+
Sbjct: 156 GVAINERRGYGFPVDWWSLGVSLFELLKKRRPF 58
>06405
          Length = 1965

 Score = 82.4 bits (202), Expect = 5e-16,   Method: Compositional matrix adjust.
 Identities = 63/259 (24%), Positives = 113/259 (43%), Gaps = 10/259 (3%)
 Frame = +1

Query: 253 EKIGQGASGTVFTATDVALGQEVAIKQINLQKQPKKELIINEILVMKELKNPNIVNFLDS 312
            ++G G  G V+ A      + VA+K +        + +  E  +MKE+K+PN+V  L  
Sbjct: 277 HRLGGGQYGDVYEAMWKRYNKIVAVKTLKEDTMALNDFL-EEAAIMKEMKHPNLVQLLGV 453

Query: 313 YLVGDELFVVMEYLAGGSLTDVVTETCMDEAQIAAVCRECLQ---ALEFLHANQVIHRDI 369
                  ++V E++  G+L D +  +  +E    A+     Q    + +L     IHRD+
Sbjct: 454 CTREPPFYIVTEFMPHGNLLDYLRSSTREENGPTALMYMATQIASGMAYLETKNFIHRDL 633

Query: 370 KSDNVLLGMEGSVKLTDFGFCAQITPEQSKRSTMVGTPY---WMAPEVVTRKAYGPKVDI 426
            + N L+     VK+ DFG    +  +    +  +G  +   W APE +    +  + DI
Sbjct: 634 AARNCLVADSNMVKVADFGLARLM--KDDTYTAHIGAKFPIKWTAPEGLAFNRFSTRSDI 807

Query: 427 WSLGIMAIEMVE-GEPPYLNENPLRALYLIATNGTPELQNPEKLSPIFRDFLNRCLEMDV 485
           W+ G++  E+   G  PY     L  +Y +   G   ++ P          + +C + D 
Sbjct: 808 WAFGVLLWELATYGMSPYPGVE-LTEVYHLLERGY-RMERPPGTPADVYILMLKCWQWDP 981

Query: 486 EKRGSAKE---LLQHPFLK 501
           + R + KE   LL++ F K
Sbjct: 982 KDRPTFKEIHFLLENMFEK 1038
>01756
          Length = 1858

 Score = 80.1 bits (196), Expect = 2e-15,   Method: Compositional matrix adjust.
 Identities = 60/219 (27%), Positives = 104/219 (47%), Gaps = 21/219 (9%)
 Frame = -3

Query: 244  DPKKKYTRYEKIGQGASGTVFTATDVALGQEVAIKQINLQKQPKKELI--INEILVMKEL 301
            D   KY +  KIGQG  G VF A      Q VA+K++ +  + +   I  + EI +++ L
Sbjct: 1751 DEDAKYEKLAKIGQGTFGEVFKARCKKTKQVVAMKKVLMDNEKEGFPITALREIKILQLL 1572

Query: 302  KNPNIVNFLD---------------SYLVGDELFVVMEYLAGGSLTDVVTETCMDEAQIA 346
             + N+V+ ++                YLV    F   E+   G L+++      +  +I 
Sbjct: 1571 NHENVVDLIEICSTKATSANRYKSMFYLV----FEFCEHDLAGLLSNM--SVVFNLPEIK 1410

Query: 347  AVCRECLQALEFLHANQVIHRDIKSDNVLLGMEGSVKLTDFGFCA--QITPEQSKRST-M 403
             V ++ +  L ++H N+++HRD+K+ N+L+  +G +KL DFG      +   Q  R T  
Sbjct: 1409 EVMKQLMNGLYYIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNR 1230

Query: 404  VGTPYWMAPEVVT-RKAYGPKVDIWSLGIMAIEMVEGEP 441
            V T ++  PE++   + Y   +D W  G +  EM    P
Sbjct: 1229 VVTLWYRPPELLLGDRNYSTAIDQWGAGCIMAEMWTRNP 1113
>04852
          Length = 1462

 Score = 78.2 bits (191), Expect = 7e-15,   Method: Compositional matrix adjust.
 Identities = 68/256 (26%), Positives = 111/256 (43%), Gaps = 33/256 (12%)
 Frame = +1

Query: 275 VAIKQI-NLQKQPKKELIINEILVMKELK----NPNIVNFLDSYLVGDELFVVMEYLAGG 329
           VA+K + ++    +++  + E+ VMK +K    + NIVNFL     G  L+V++E+   G
Sbjct: 28  VAVKMLRDIVTAVEEQDFVQELQVMKAVKKMGSHINIVNFLGCCTQGGPLWVIVEFAKNG 207

Query: 330 SLTDVVTETCMD---------------------------EAQIAAVCRECLQALEFLHAN 362
           +L D + E+C D                              + +   +  + +EFL + 
Sbjct: 208 NLRDFL-ESCRDGINGYGKFVSPQDPGWYTKTPGGHVIRRKNLLSYAFQIARGMEFLASR 384

Query: 363 QVIHRDIKSDNVLLGMEGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGP 422
           + IHRD+ + NVL+  E  +K+ DFG  ++      KRS       WMAPE +    Y  
Sbjct: 385 KCIHRDLAARNVLVTEEHVLKIADFGL-SRTGDYYKKRSGGRLPVKWMAPEALFDMRYTT 561

Query: 423 KVDIWSLGIMAIEMVE-GEPPYLNENPLRALYLIATNGTPELQNPEKLSPIFRDFLNRCL 481
           K D+WS G++  E+   G  PY +  P   LY    +    +  PE  S      + RC 
Sbjct: 562 KSDVWSFGVVLWEIFSLGGMPYAS-IPNEELYSKLLDDAYRMPRPELASGNLYAIMERCW 738

Query: 482 EMDVEKRGSAKELLQH 497
                 R    +L+ H
Sbjct: 739 LNRPSDRPEFSQLVGH 786
>02638
          Length = 1490

 Score = 78.2 bits (191), Expect = 8e-15,   Method: Compositional matrix adjust.
 Identities = 42/104 (40%), Positives = 62/104 (59%), Gaps = 3/104 (2%)
 Frame = +1

Query: 400 RSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNE---NPLRALYLIA 456
           +  ++GT  +MAPEV+  ++YG   D+WS+G + IEM    PP+ +    N L  ++ IA
Sbjct: 7   QGQLLGTIAFMAPEVLRGESYGRACDVWSVGCVMIEMCTCRPPWNSHDISNHLALIFKIA 186

Query: 457 TNGTPELQNPEKLSPIFRDFLNRCLEMDVEKRGSAKELLQHPFL 500
           ++  P    PE +SP  RD + RCLE D + R SAK+LL HP  
Sbjct: 187 SSVDPP-PIPENMSPPVRDLMLRCLEQDSDFRPSAKDLLMHPLF 315
>13066
          Length = 551

 Score = 77.8 bits (190), Expect = 1e-14,   Method: Compositional matrix adjust.
 Identities = 55/165 (33%), Positives = 83/165 (50%), Gaps = 8/165 (4%)
 Frame = +3

Query: 274 EVAIKQINLQKQPK---KELIINEILVMKELKNPNIVNFLDSYLVGDELFVVMEYLAGGS 330
           ++A K I+ +K P    ++    E+ ++ +L +P I+          + F+ M +   G 
Sbjct: 57  KLACKIIDKEKAPVDFVEKFFPRELDLLTKLDHPYIIQIHSILQRXPKNFIFMRFAERGD 236

Query: 331 LTDVVTET-CMDEAQIAAVCRECLQALEFLHANQVIHRDIKSDNVLLGMEGSVKLTDFGF 389
           L   + E   + E Q      +   AL +LH+  V HRD+K +N+LL    +VKL DFGF
Sbjct: 237 LLTYIQEVGFVKEKQAKIWFYQMTTALNYLHSYDVAHRDLKCENILLSSHFNVKLADFGF 416

Query: 390 -CAQITP--EQSKRSTMVGTPYWMAPEVVTRKAYGPKV-DIWSLG 430
            CA IT   E+    T  G+  + APE+V    Y PKV D WSLG
Sbjct: 417 ACACITESGEKYMSRTYCGSAAYAAPEIVYGAPYAPKVADAWSLG 551
>29581
          Length = 1278

 Score = 77.0 bits (188), Expect = 2e-14,   Method: Compositional matrix adjust.
 Identities = 55/168 (32%), Positives = 87/168 (51%), Gaps = 7/168 (4%)
 Frame = -2

Query: 301  LKNPNIVNFLDSYLVG---DELFVVMEYLAG--GSLTDVVTETCMDEAQIAAVCRECLQA 355
            L++ NIV  L   +VG   D LF+VMEY      SL D +      E+Q+  +  + L+ 
Sbjct: 1184 LRHQNIVQ-LQEVVVGKSLDSLFLVMEYCEQDLASLLDNMPAP-FSESQVKCIVLQLLKG 1011

Query: 356  LEFLHANQVIHRDIKSDNVLLGMEGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVV 415
            L +LH   +IHRD+K  N+L+  +G VK+ DFG        Q   +  V T ++ APE++
Sbjct: 1010 LRYLHEAFIIHRDLKVSNLLMTDKGCVKIADFGLARNYGKPQKPMTPKVVTLWYRAPELL 831

Query: 416  -TRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIA-TNGTP 461
               K +   +D+WS G +  E++  +P     + L+ + LI    GTP
Sbjct: 830  FGSKTHSTAIDMWSAGCILGELLGHKPLMPGRSDLQQIELIMELLGTP 687
>21433
          Length = 590

 Score = 73.6 bits (179), Expect = 2e-13,   Method: Compositional matrix adjust.
 Identities = 40/89 (44%), Positives = 60/89 (67%)
 Frame = +2

Query: 354 QALEFLHANQVIHRDIKSDNVLLGMEGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPE 413
            ALE+ H  +VIHRDIK +N+LLG++G +K+ DFG+   +    S+R+TM GT  ++ PE
Sbjct: 200 SALEYCHYRKVIHRDIKPENLLLGLKGDLKIADFGW--SVHAPSSRRTTMCGTLDYLPPE 373

Query: 414 VVTRKAYGPKVDIWSLGIMAIEMVEGEPP 442
           +V  K +   VD+WSLG++  E + G PP
Sbjct: 374 MVEGKTHDENVDLWSLGVLCYEFLVGTPP 460
>01392
          Length = 1806

 Score = 71.6 bits (174), Expect = 8e-13,   Method: Compositional matrix adjust.
 Identities = 58/210 (27%), Positives = 96/210 (45%), Gaps = 30/210 (14%)
 Frame = -1

Query: 342  EAQIAAVCRECLQALEFLHANQVIHRDIKSDNVLLGMEGS---VKLTDFGFCAQITPEQS 398
            E + + V R   +AL+FLH+  + HRD+K +N+L         VK+ DF   + I+ +  
Sbjct: 1794 EREASLVVRHIARALDFLHSKGIAHRDLKPENILCEHLDDVVPVKICDFDLASGISCDGD 1615

Query: 399  KRS-----TMVGTPYWMAPEVVTRK-----AYGPKVDIWSLGIMAIEMVEGEPPYLNE-- 446
                    T VG+  +MAPEVV        +Y  + D+WSLGI+   M+ G PP+  +  
Sbjct: 1614 GTKTPELLTPVGSAEYMAPEVVDAWVGDSFSYDKRCDLWSLGIILYIMLCGYPPFYGQCG 1435

Query: 447  ------------NPLRALYLIATNGTPEL--QNPEKLSPIFRDFLNRCLEMDVEKRGSAK 492
                        +    L+    +G  +   Q    +S   +D +   L  +  KR SA 
Sbjct: 1434 EDCGWNRGEACHDCQDMLFNSIQDGHYKFPSQEWTSISSSAKDLIRHLLVREPRKRYSAA 1255

Query: 493  ELLQHPFLKLAKPLSSL-TPLILAAKEAMK 521
            ++L+HP++      + L TP +L    +MK
Sbjct: 1254 DVLKHPWICTPPAATQLATPHVLTRNNSMK 1165
>04591
          Length = 1117

 Score = 70.9 bits (172), Expect = 1e-12,   Method: Compositional matrix adjust.
 Identities = 47/167 (28%), Positives = 84/167 (50%), Gaps = 17/167 (10%)
 Frame = -2

Query: 292  INEILVMKELKNPNIVNFLD---------------SYLVGDELFVVMEYLAGGSLTDVVT 336
            + EI ++++L++ N+V   +                YL+    F   +Y   G L ++  
Sbjct: 1077 LREIKILQQLEHENVVQLQEICHTQAGPYNRYKSTFYLI----FEYCDYDLAGLLNNLRV 910

Query: 337  ETCMDEAQIAAVCRECLQALEFLHANQVIHRDIKSDNVLLGMEGSVKLTDFGFCAQITPE 396
            +  +  A    +  + L  L ++H  Q++HRDIK+ N+LL  +G +KL DFG        
Sbjct: 909  KFSL--ADKKNLMSQLLNGLFYIHTKQILHRDIKAANILLTRDGVLKLADFGLSRPWV-- 742

Query: 397  QSKRST-MVGTPYWMAPEVVT-RKAYGPKVDIWSLGIMAIEMVEGEP 441
            +SKR T  V T ++  PE++   + YGP++D+W +G +  EM   +P
Sbjct: 741  KSKRLTNRVVTLWYRPPELLLGEREYGPEIDMWGVGCIMAEMWSRKP 601
>01966
          Length = 1735

 Score = 70.9 bits (172), Expect = 1e-12,   Method: Compositional matrix adjust.
 Identities = 58/235 (24%), Positives = 106/235 (45%), Gaps = 7/235 (2%)
 Frame = -1

Query: 270  ALGQEVAIKQINLQKQPKK--ELIINEILVMKELKNPNIVNFLDSYLVGDELFVVMEYLA 327
            A G+++A+K+I L+          I EI +++EL++ NIV   D  +  + LF+V E+L+
Sbjct: 1642 ATGRKLAMKKIRLRGSEDGVPSSAIREIAMLRELRHTNIVCLEDVIMEDERLFLVFEFLS 1463

Query: 328  GG--SLTDVVTE-TCMDEAQIAAVCRECLQALEFLHANQVIHRDIKSDNVLLGMEGSVKL 384
                   D   E   +D   + +   + +  + F H  +++HRD+K  N+L+   G++K+
Sbjct: 1462 MDLKMYIDKFPEGVVLDRRLVKSYVFQIVTGINFCHQRRIVHRDLKPQNLLINHTGAIKI 1283

Query: 385  TDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVD--IWSLGIMAIEMVEGEPP 442
             DFG            +  V T ++ APE++     GP+     W+ G +     E   P
Sbjct: 1282 ADFGMARTFALPVRAYTHEVVTLWYRAPEILM----GPQSTPPXWTCGAL-----EPSSP 1130

Query: 443  YLNENPLRALYLIATNGTPELQNPEKLSPIFRDFLNRCLEMDVEKRGSAKELLQH 497
              +  PL      ++  TP+L +  + S          L +   +RG +    QH
Sbjct: 1129 ICSSGPL------SSRATPKLTSFLRYSG--------SLALQRNRRGPSFTSCQH 1007

 Score = 34.7 bits (78), Expect = 0.099,   Method: Compositional matrix adjust.
 Identities = 27/107 (25%), Positives = 43/107 (40%), Gaps = 26/107 (24%)
 Frame = -3

Query: 420  YGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLI-------------------ATNGT 460
            Y   VD+WS+G +  +M+   P +  ++ +  L+ I                   A NG 
Sbjct: 1175 YSTPVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIFRIIGTPTEQTWPEFHKLPAFNGM 996

Query: 461  PELQNPEKLSPIFR-------DFLNRCLEMDVEKRGSAKELLQHPFL 500
              L    KLS           D + R L+ D  +R S K++LQH + 
Sbjct: 995  FPLWKEGKLSETLTDLDSLGLDLIERTLKCDPAQRISCKKMLQHAYF 855
>19761
          Length = 473

 Score = 70.5 bits (171), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 40/146 (27%), Positives = 76/146 (52%), Gaps = 3/146 (2%)
 Frame = -3

Query: 342 EAQIAAVCRECLQALEFLHANQ--VIHRDIKSDNVLLGMEGSVKLTDFGFCAQITPEQSK 399
           E  I     +   AL ++H +   ++HRD+K  N+ +  +G V+L D G   ++T     
Sbjct: 426 ERLIVCWLMQTASALNYMHTHTPVILHRDLKPQNIYVTEKGDVRLGDLGLARKLTGPADF 247

Query: 400 RSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALY-LIATN 458
            ++ VGT  +++PE+++++ Y  K DIWSLG +  ++   +      + +  ++ L+   
Sbjct: 246 ATSQVGTIMYLSPEILSQQPYNSKSDIWSLGCVFYDITGKK----GSDEMGVMFLLVQVM 79

Query: 459 GTPELQNPEKLSPIFRDFLNRCLEMD 484
           G  +L  P+  S  FRD ++R L  D
Sbjct: 78  GGRKLPLPDHYSQEFRDTISRMLTKD 1
>27546
          Length = 426

 Score = 70.5 bits (171), Expect = 2e-12,   Method: Composition-based stats.
 Identities = 40/128 (31%), Positives = 68/128 (53%), Gaps = 4/128 (3%)
 Frame = -1

Query: 266 ATDVALGQEVAIKQINLQKQP---KKELIINEILVMKELKNPNIVNFLDSYLVGDELFVV 322
           A +   G  +A K I+  K P    K+    E+ ++  L +PNI+        G ++F+ 
Sbjct: 423 ADESGHGVNLACKIIDKAKAPIDFVKKFFPRELEILTRLDHPNIIQIHSILQRGPKIFIF 244

Query: 323 MEYLAGGSLTDVVTETC-MDEAQIAAVCRECLQALEFLHANQVIHRDIKSDNVLLGMEGS 381
           M Y   G +   + +T  +DEAQ      +  +AL++LH++ + HRD+K +N+LL    +
Sbjct: 243 MRYAEKGDMLSHIKKTGPIDEAQTKVWFFQMAKALQYLHSHDIAHRDLKCENILLSKRLN 64

Query: 382 VKLTDFGF 389
           VK+ DFGF
Sbjct: 63  VKIADFGF 40
>21808
          Length = 1011

 Score = 70.1 bits (170), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 45/173 (26%), Positives = 79/173 (45%), Gaps = 4/173 (2%)
 Frame = +1

Query: 275 VAIKQINLQKQPKKELIINEILVMKELKNPNIVNFLDSYLVGDELFVVMEYLAGGSLTDV 334
           VAIK +       K+ +  E  +MK+L++P ++         D +F++ E +  GSL + 
Sbjct: 28  VAIKTLKSGTMDPKDFLA-EAQIMKKLRHPKLIQLYAVCTQDDPIFIITELMKNGSLLEF 204

Query: 335 VTET--CMDEAQIAAVCRECLQALEFLHANQVIHRDIKSDNVLLGMEGSVKLTDFGFCAQ 392
           +      +    +  +  +    + +L +   IHRD+ + N+L+    +VK+ DFG    
Sbjct: 205 LQGKGRVLKLPALIDIGAQIACGMAYLESQNYIHRDLAARNILVSDNNTVKIADFGLARV 384

Query: 393 ITPEQSKRSTMVGTPY-WMAPEVVTRKAYGPKVDIWSLGIMAIEMVE-GEPPY 443
           I  ++ +       P  W APE      +  K D+WS GI+  E V  G  PY
Sbjct: 385 IKEDEYEARVGARFPIKWTAPEAANYNRFTIKSDVWSFGILLTETVTYGRVPY 543
>19301
          Length = 712

 Score = 69.3 bits (168), Expect = 3e-12,   Method: Compositional matrix adjust.
 Identities = 44/145 (30%), Positives = 77/145 (53%), Gaps = 1/145 (0%)
 Frame = +2

Query: 245 PKKKYTRYEKIGQGASGTVFTATDVALGQEVAIKQINLQKQPKKELIINEILVMKELKNP 304
           P +  T  E +G GA G VF     A  +EVA+K++   K+        +I  +++L +P
Sbjct: 299 PFESITDLEWLGSGAQGAVFLGKLCA--EEVAVKKVRDIKE-------TDIRNLRKLNHP 451

Query: 305 NIVNFLDSYLVGDELFVVMEYLAGGSLTDVVTETC-MDEAQIAAVCRECLQALEFLHANQ 363
           NI++F           ++MEY   G L +V+ +   +  A +    ++    + +LH+++
Sbjct: 452 NIISFKGVCTQAPCYCIIMEYCPYGQLYEVLRDGKEIPPALVLDWSKQIASGMNYLHSHK 631

Query: 364 VIHRDIKSDNVLLGMEGSVKLTDFG 388
           +IHRD+KS NVL+     VK++DFG
Sbjct: 632 IIHRDLKSPNVLVAKNDVVKISDFG 706
>11780
          Length = 1713

 Score = 69.3 bits (168), Expect = 3e-12,   Method: Compositional matrix adjust.
 Identities = 51/168 (30%), Positives = 86/168 (51%), Gaps = 5/168 (2%)
 Frame = +3

Query: 253 EKIGQGASGTVFTATDVALGQEVAIKQINLQKQPKKELIINEILVMKELKNPNIVNFLDS 312
           E IG+G  G V+    +  GQ VAIKQ+   K   ++  + E  VM  L++ N+V  +  
Sbjct: 615 EAIGKGDFGDVYKG--MYRGQPVAIKQLK-DKDRGEQSFLQEASVMTSLRHDNLVRLI-G 782

Query: 313 YLVGDELFVVMEYLAGGSLTDVVTE----TCMDEAQIAAVCRECLQALEFLHANQVIHRD 368
            ++G+ +F+V E++  G+L + +          + QI      C  A+E+L + +++HRD
Sbjct: 783 VVLGETIFLVTEFMGKGNLVEYLRSRGRSVITKKDQINFATDTC-AAMEYLESKRLVHRD 959

Query: 369 IKSDNVLLGMEGSVKLTDFGFCAQITPEQSKRSTMVGTPY-WMAPEVV 415
           + + NVL+  +G  K++DFG        Q    T V  P  W APE +
Sbjct: 960 LAARNVLVHDDGKAKVSDFGLAKFGDFSQ----TSVKFPIKWTAPEAL 1091
>09007
          Length = 1440

 Score = 67.4 bits (163), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 58/256 (22%), Positives = 114/256 (44%), Gaps = 15/256 (5%)
 Frame = -1

Query: 255 IGQGASGTVFTATDVALGQE---VAIKQINLQKQPKK-ELIINEILVMKELKNPNIVNFL 310
           +GQG  GTV  A   A   E   VA+K ++  K  K  +  + E  +M+ L + NIV   
Sbjct: 855 LGQGHFGTVRQAIWTAESGEKVQVAVKCLSKDKIHKDGQEFLKETAIMQMLDHENIVRVY 676

Query: 311 DSYL-VGDELFVVMEYLAGGSLTDVVTETCMD-EAQIAAVC---RECLQALEFLHANQVI 365
              +  G ++ +V E     SL + V E     +  +  +C   ++    + +L + +++
Sbjct: 675 GVVMDNGADIMLVTELAPMRSLLECVKEVSARVDFSVPRLCDFSQQVCDGMSYLESKRLV 496

Query: 366 HRDIKSDNVLLGMEGSVKLTDFGFCAQITP----EQSKRSTMVGTPY-WMAPEVVTRKAY 420
           HRD+ + N+LL  +  VK++D G    +       QS+++  +     W APE      +
Sbjct: 495 HRDLAARNILLFSKSKVKISDVGVSGALGAGKEYYQSQQTIHLQNAVAWCAPESFRNLCF 316

Query: 421 GPKVDIWSLGIMAIE-MVEGEPPYLNENPLRALYLIATNGTPELQNPEKLSPIFRDFLNR 479
               D+W+ G++  E    G  P+   N  + +  +    +  L+ P+     +   + +
Sbjct: 315 SSASDVWAFGVLLWEFFTHGFQPWAGLNGQQIMEAVDAPQSQRLEQPDLCPKEYYAVMLK 136

Query: 480 CLEMDVEKRGSAKELL 495
           C E + ++R +  +L 
Sbjct: 135 CWEQEPQRRPTFSQLF 88
>21079
          Length = 878

 Score = 66.2 bits (160), Expect(2) = 1e-11,   Method: Compositional matrix adjust.
 Identities = 38/144 (26%), Positives = 71/144 (49%), Gaps = 4/144 (2%)
 Frame = +1

Query: 303 NPNIVNFLDSYLVGDELFVVMEYLAGGSLTDVVT--ETCMDEAQIAAVCRECLQALEFLH 360
           +P ++   D++     + +VME++  G L + V   +  + E       R+    + ++H
Sbjct: 1   HPKLLMLWDAFEAPRTMVLVMEFVGAGELFERVIRDDFVLTERDCVHFVRQICSGVGYMH 180

Query: 361 ANQVIHRDIKSDNVLLGMEGS--VKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRK 418
              ++H D+K +NVL   + S  +K+ DFG      P  S +  + GTP ++APEVV   
Sbjct: 181 TQSILHLDLKPENVLCVSDNSNQIKIIDFGLARFYKPGDSLQ-VLFGTPEFIAPEVVNYD 357

Query: 419 AYGPKVDIWSLGIMAIEMVEGEPP 442
                 D+WS+G++   ++ G  P
Sbjct: 358 EINFTTDMWSIGVICYILLSGLSP 429

 Score = 21.2 bits (43), Expect(2) = 1e-11,   Method: Compositional matrix adjust.
 Identities = 8/27 (29%), Positives = 16/27 (59%)
 Frame = +2

Query: 474 RDFLNRCLEMDVEKRGSAKELLQHPFL 500
           +DF+  C   + EKR + ++  +H +L
Sbjct: 524 KDFIGNC*SREKEKRMTIEQCDKHSWL 604
>00715
          Length = 1788

 Score = 67.0 bits (162), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 54/238 (22%), Positives = 108/238 (45%), Gaps = 34/238 (14%)
 Frame = +1

Query: 293 NEILVMK-ELKNPNIVNFLDS---YLVGDELFVVMEYLAGGSLTDVVT--ETCMDEAQIA 346
           NE+L  +  L++ N+V+ L +   +   D  ++ MEY+   +L  ++   +  +D +   
Sbjct: 70  NELLAFRCGLRHVNVVSILGATSLHRFEDGAWLAMEYVGPLNLQTILNDHQQDIDSSMRL 249

Query: 347 AVCRECLQALEFLHANQVIHRDIKSDNVLLGMEGSVKLTDFGFCAQITP----------- 395
           ++  +  + L +LH+  ++H D+K  N LL  +  +++ DFG C Q+TP           
Sbjct: 250 SLALQMARGLHYLHSINIVHLDLKPANCLLTRDLKLRIADFGCCHQLTPTGLDMGEREGG 429

Query: 396 -----------EQSKRSTMVGTPYWMAPEVVTRKAYGPKV--DIWSLGIMAIEMVEGEPP 442
                      + + ++ + GT  + APE++  K   P V  D++SLGI   +M   + P
Sbjct: 430 MAGNELELTPVQGAWKNELAGTLAYRAPELL--KGLQPSVRSDVYSLGITLWQMCTRQGP 603

Query: 443 YLNENPLRALYLIATNGT----PELQNPEKLSPIFRDFLNRCLEMDVEKRGSAKELLQ 496
           Y        +Y + +       P     +    +FRD   +C    VE R ++ +++ 
Sbjct: 604 YEGVPAHAVVYQVVSKDLRPCPPPSTEDDPFEVMFRDLYTQCWARRVEDRPTSLDVVH 777
>12786
          Length = 460

 Score = 65.9 bits (159), Expect = 4e-11,   Method: Compositional matrix adjust.
 Identities = 41/129 (31%), Positives = 64/129 (49%), Gaps = 22/129 (17%)
 Frame = -3

Query: 337 ETCMDEAQIAAVCRECLQALEFLHANQVIHRDIKSDNVLLGMEGSVKLTDFGFCAQITPE 396
           E  +D   I    RE L+A++ LH   VIH D+K  N +L + G++KL DFG    +  +
Sbjct: 428 EQGLDRMMIKFYWREMLRAVKALHNEGVIHSDLKPANFML-VAGNLKLIDFGIANTLQQD 252

Query: 397 QSK--RSTMVGTPYWMAPEVV------------------TRKAY--GPKVDIWSLGIMAI 434
           ++   + + VGTP +M+PE +                  T+  Y  G + D+WSLG +  
Sbjct: 251 KTSVLKDSRVGTPSYMSPEAIMAACDDSADDSMEEDGHRTKPKYKVGVRSDVWSLGCILY 72

Query: 435 EMVEGEPPY 443
            MV G  P+
Sbjct: 71  NMVYGRTPF 45
>17975
          Length = 449

 Score = 65.5 bits (158), Expect = 5e-11,   Method: Composition-based stats.
 Identities = 39/129 (30%), Positives = 71/129 (55%), Gaps = 5/129 (3%)
 Frame = +3

Query: 266 ATDVALGQEVAIKQINLQK--QPKKELIINEILVMKELKNPNIVNFLDSYLVGDELFVVM 323
           A  V  G++VA+K I+  K  +  +  +  E+  MK +++PN+V   +      +L++++
Sbjct: 24  ARHVFTGEKVAVKVIDKTKLDEVSRSHLFQEVRCMKLVQHPNVVRLYEVIDTQTKLYLIL 203

Query: 324 EYLAGGSLTDVVTETC--MDEAQIAAVCRECLQALEFLHANQVIHRDIKSDNVLLGME-G 380
           E   GG + D +      ++E       R+ ++A+ + H   V+HRD+K +NV+   + G
Sbjct: 204 ELGDGGDMYDYIMRHSGGLEEKLAKRYFRQIVEAISYCHKLHVVHRDLKPENVVFFEKPG 383

Query: 381 SVKLTDFGF 389
            VKLTDFGF
Sbjct: 384 LVKLTDFGF 410
>26560
          Length = 398

 Score = 64.7 bits (156), Expect = 8e-11,   Method: Composition-based stats.
 Identities = 33/107 (30%), Positives = 59/107 (55%), Gaps = 1/107 (0%)
 Frame = -1

Query: 342 EAQIAAVCRECLQALEFLHANQVIHRDIKSDNVLLGMEGSVKLTDFGFCAQITPEQSKRS 401
           E ++     E +  LE +H+  V++RD+K  N+LL   G V+++D G     + ++   S
Sbjct: 359 EKEVRFYAAEVMLGLEHMHSRFVVYRDLKPANILLDENGHVRISDLGLACDFSKKRPHAS 180

Query: 402 TMVGTPYWMAPEVVTR-KAYGPKVDIWSLGIMAIEMVEGEPPYLNEN 447
             VGT  +MAPEV+ + ++Y    D +S G M  ++++G  P+   N
Sbjct: 179 --VGTHGYMAPEVLMKGQSYDSSADWFSFGCMLYKLLKGHSPFRQHN 45
>07940
          Length = 1336

 Score = 64.3 bits (155), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 33/93 (35%), Positives = 49/93 (52%), Gaps = 3/93 (3%)
 Frame = -3

Query: 354 QALEFLHANQVIHRDIKSDNVLLGMEGSVKLTDFGFCAQITPEQSKRSTMVGT--PYWMA 411
           + +E+L + Q IHRD+ + NVL+  E  +K+ DFG    +      R T  G     WMA
Sbjct: 314 RGMEYLASKQCIHRDLAARNVLVAEEYVLKIADFGLTRNLQQFDYYRKTTDGRLPVKWMA 135

Query: 412 PEVVTRKAYGPKVDIWSLGIMAIEMVE-GEPPY 443
           PE +  + Y  K D+WS G++  E+   G  PY
Sbjct: 134 PEALFDRKYTSKSDVWSYGVLLWEIFTLGGNPY 36
>14116
          Length = 1017

 Score = 62.4 bits (150), Expect = 4e-10,   Method: Compositional matrix adjust.
 Identities = 57/224 (25%), Positives = 107/224 (47%), Gaps = 15/224 (6%)
 Frame = -1

Query: 229 DEEIMEKLRTIVSIGDPKKKYTRYEKIGQGASGTV----FTATDVALGQEVAIKQINLQK 284
           DE++M KL    S+   ++  T  E+IG+G  G V     T  +      VA+K ++   
Sbjct: 687 DEDMM-KLIENESLLIDREFLTMGEEIGKGNFGCVKRGFLTLPEQKGDILVAVKTLHNNN 511

Query: 285 QPKKEL--IINEILVMKELKNPNIVNFLDSYLVGDEL-FVVMEYLAGGSLTDVVTETCMD 341
             + EL   + E L+MK+  + N++  +   L  D++  VV+ ++  G L   + +   D
Sbjct: 510 PREIELQSFLQEALIMKDFHHSNVLTLIGICLNLDDMPLVVLPFMKHGDLLTYIRD---D 340

Query: 342 EAQ-----IAAVCRECLQALEFLHANQVIHRDIKSDNVLLGMEGSVKLTDFGFCAQITPE 396
           + Q     +     +  + +++L   + +HRD+ + N +L  +  VK+ DFG    I  +
Sbjct: 339 QHQPTIKDLIMYGVDIARGMDYLAGLKFVHRDLAARNCMLDEDFHVKVADFGLARDIYEK 160

Query: 397 Q--SKRSTMVGTPY-WMAPEVVTRKAYGPKVDIWSLGIMAIEMV 437
           +  S  +     P  WMA E + +  Y  K D+WS G++  E++
Sbjct: 159 EYYSSENKKAKLPVKWMALESLEKGNYDSKTDVWSYGVVLWELL 28
>25019
          Length = 730

 Score = 62.4 bits (150), Expect = 5e-10,   Method: Compositional matrix adjust.
 Identities = 29/60 (48%), Positives = 37/60 (61%)
 Frame = +3

Query: 371 SDNVLLGMEGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLG 430
           ++NVLL  +G VKLTDFG C +         T  GT  +MAPE++TR  +G  VD WSLG
Sbjct: 258 AENVLLDKDGHVKLTDFGLCKEAITGTRVTHTFCGTIEYMAPEILTRTGHGKAVDWWSLG 437
>26711
          Length = 405

 Score = 61.2 bits (147), Expect = 9e-10,   Method: Composition-based stats.
 Identities = 33/108 (30%), Positives = 58/108 (53%), Gaps = 2/108 (1%)
 Frame = -2

Query: 347 AVCRECLQALEFLHANQVIHRDIKSDNVLLGME--GSVKLTDFGFCAQITPEQSKRSTMV 404
            V ++ L  L+ +HA  V+H D+K  N+LL  +   SV+L DFG   ++ P Q       
Sbjct: 404 GVVKQVLDILQHVHAQGVVHMDLKPSNLLLSGDKLDSVQLIDFGLARKLYPPQETFLNH- 228

Query: 405 GTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRAL 452
           GTP + +PE +  K      D+W +G++A  ++ G+ P+  ++   +L
Sbjct: 227 GTPGFTSPEALDVKPISTASDVWGVGVLAYILLSGQSPFQADSATESL 84
>04138
          Length = 800

 Score = 60.1 bits (144), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 49/189 (25%), Positives = 83/189 (43%), Gaps = 35/189 (18%)
 Frame = +1

Query: 347 AVCRECLQALEFLHANQVIHRDIKSDNVLLGMEGSVKLTDFGFCA--QITPEQSKRST-M 403
           ++C    + L ++H N+++HRD+K+ N+L+  +G +KL DFG      +   Q  R T  
Sbjct: 25  SIC*AADERLYYIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNR 204

Query: 404 VGTPYWMAPEVVT-RKAYGPKVDIWSLGIMAIEMVEGEPPY---LNENPLRALYLIATNG 459
           V T ++  PE++   + Y   +D W  G +  EM    P       +N L  +  +  + 
Sbjct: 205 VVTLWYRPPELLLGDRNYSTAIDQWGAGCIMAEMWTRNPIMQGTTEQNQLTLITQLCGSI 384

Query: 460 TPEL---------------------QN--PEKLSPIFR-----DFLNRCLEMDVEKRGSA 491
           TPE+                     +N   ++ + I +     D   R L+MD  +R SA
Sbjct: 385 TPEVWPGVTQLSMYHQIKGALAAGRKNIIRDRFARILKDPYGLDLFERLLKMDPSQRISA 564

Query: 492 KELLQHPFL 500
            E L H F 
Sbjct: 565 DEALNHDFF 591
>27405
          Length = 532

 Score = 58.5 bits (140), Expect = 6e-09,   Method: Compositional matrix adjust.
 Identities = 44/176 (25%), Positives = 89/176 (50%), Gaps = 9/176 (5%)
 Frame = -3

Query: 261 GTVFTATDVALGQEVAIKQIN---LQKQPKKELIINEILVMKELK----NPNIVNFLDSY 313
           G V+       G+  A+K ++   ++ +  + L +NE +++  +     +P IV    ++
Sbjct: 524 GEVYGCRKADTGKMYAMKCLDKKRIKMKGGETLALNERIMLSLVSTGEGSPFIVCMTYAF 345

Query: 314 LVGDELFVVMEYLAGGSLTDVVTET-CMDEAQIAAVCRECLQALEFLHANQVIHRDIKSD 372
              ++L  +++ + GG L   +++     E ++     E +  LE +H+  V++RD+K  
Sbjct: 344 QTPEKLCFILDLMNGGDLHYHLSQHGVFTEKEVRFYAAEVMLGLEHMHSRFVVYRDLKPA 165

Query: 373 NVLLGMEGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTR-KAYGPKVDIW 427
           N+LL   G V+++D G     + ++   S  VGT  +MAPEV+ + +AY    D W
Sbjct: 164 NILLDENGHVRISDLGLACDFSKKKPHAS--VGTHGYMAPEVLMKGQAYDSSAD-W 6
>07836
          Length = 1478

 Score = 57.4 bits (137), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 42/160 (26%), Positives = 73/160 (45%), Gaps = 16/160 (10%)
 Frame = -1

Query: 272  GQEVAIKQINLQKQPKKELIINEILVMKELKNPNIVNFLDSYLVGD----ELFVVMEYLA 327
            G+ VA+K I    +        E+     L++ NI+ F+ + + G     +LF++ +Y  
Sbjct: 1478 GENVAVK-IFFTTEEASWFRETELYQTVLLRHENILGFIAADIKGTGSWTQLFLITDYHE 1302

Query: 328  GGSLTDVVTETCMDEAQIAAVCRECLQALEFLHAN--------QVIHRDIKSDNVLLGME 379
             GSL D +    +D +++ A+    +  L  LH           + HRDIKS N+L+   
Sbjct: 1301 NGSLHDYLLSRVLDSSEMLALAHSAICGLAHLHIEIFGTRGKPAIAHRDIKSKNILVKKN 1122

Query: 380  GSVKLTDFGFCAQITPEQSKRSTM----VGTPYWMAPEVV 415
            G+  + D G   +   E ++         GT  +MAPEV+
Sbjct: 1121 GTCCIADLGLAVRYISESNEVDVAPNPRQGTKRYMAPEVL 1002
>18663
          Length = 600

 Score = 56.6 bits (135), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 34/114 (29%), Positives = 58/114 (50%), Gaps = 12/114 (10%)
 Frame = +2

Query: 401 STMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPY----LNENPLRAL--YL 454
           ST  GTP ++APE++  + YG  VD W+LG++  EM+ G  P+     +ENP +    YL
Sbjct: 2   STFCGTPNYIAPEILRGEDYGFSVDWWALGVLLYEMLAGRSPFDIAGASENPDQNTEDYL 181

Query: 455 IATNGTPELQNPEKLS----PIFRDFLNR--CLEMDVEKRGSAKELLQHPFLKL 502
                   ++ P  LS     + + FLN+     +   +  +  +++ HPF K+
Sbjct: 182 FQVILEKTIRIPRSLSVKAASVLKGFLNKNPADRLGCHRESAFMDIVNHPFFKV 343
>21210
          Length = 518

 Score = 55.8 bits (133), Expect = 4e-08,   Method: Composition-based stats.
 Identities = 35/101 (34%), Positives = 52/101 (51%), Gaps = 5/101 (4%)
 Frame = +3

Query: 407 PYWMAPEVVTRKA----YGPKVDIWSLGIMAIEMVEGEPPYLN-ENPLRALYLIATNGTP 461
           PY MAPE +  +A    Y  + D+WSLGI  +E+  G  PY    +    L  +     P
Sbjct: 15  PY-MAPERIDPRASSHGYDVRSDVWSLGITLMELATGRFPYRKWVSIFDQLQQVVRGVAP 191

Query: 462 ELQNPEKLSPIFRDFLNRCLEMDVEKRGSAKELLQHPFLKL 502
            L +    S  F +F+N+CL  D ++R    +LL HPF++L
Sbjct: 192 CLPHDGAFSHDFVNFVNKCLTKDEKQRPKYNKLLAHPFVRL 314
>07291
          Length = 833

 Score = 55.8 bits (133), Expect = 4e-08,   Method: Compositional matrix adjust.
 Identities = 26/104 (25%), Positives = 53/104 (50%), Gaps = 4/104 (3%)
 Frame = +1

Query: 344 QIAAVCRECLQALEFLHANQVIHRDIKSDNVLLGMEGSVKLTDFGFCAQITPEQ---SKR 400
           Q+    R+    + +L   +V+HR++ + N ++  +G ++L+D+G    + P+    +  
Sbjct: 52  QLLDFGRQIADGMAYLQEVKVVHRNLAARNCIVTEDGRLQLSDYGVTGSLFPQSYYTADD 231

Query: 401 STMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMV-EGEPPY 443
           S       WMAPE +    +  K D+W+ G++  E++  G  PY
Sbjct: 232 SPARDLVKWMAPETIDNFHFSSKSDVWAFGVVLWELLTRGITPY 363
>03508
          Length = 1463

 Score = 55.1 bits (131), Expect = 7e-08,   Method: Compositional matrix adjust.
 Identities = 31/105 (29%), Positives = 56/105 (53%), Gaps = 2/105 (1%)
 Frame = +1

Query: 342 EAQIAAVCRECLQALEFLHANQVIHRDIKSDNVLLGMEG-SVKLTDFGFCAQITPEQSKR 400
           +  I     E ++AL+F H+  ++HRD+K  NV++  E   ++L D+G  A+      + 
Sbjct: 868 DYDIRFYLYELMKALDFCHSMGIMHRDVKPHNVMIDHENKKLRLIDWGL-AEFYHPGMEY 1044

Query: 401 STMVGTPYWMAPEVVT-RKAYGPKVDIWSLGIMAIEMVEGEPPYL 444
           +  V + Y+  PE++   + Y   +D+WSLG M   M+  + P L
Sbjct: 1045NVRVASRYFKGPELLLDYQMYDYSLDMWSLGCMFASMIFRKEPLL 1179

 Score = 30.8 bits (68), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 13/37 (35%), Positives = 22/37 (59%)
 Frame = +2

Query: 464  QNPEKLSPIFRDFLNRCLEMDVEKRGSAKELLQHPFL 500
            +N   +SP   DFL++ L  D  +R +A+E + HP+ 
Sbjct: 1343 ENQHLISPEALDFLDKLLRYDHNERLTAREAMDHPYF 1453
>29011
          Length = 374

 Score = 55.1 bits (131), Expect = 8e-08,   Method: Composition-based stats.
 Identities = 29/66 (43%), Positives = 42/66 (63%), Gaps = 5/66 (7%)
 Frame = +2

Query: 460 TPELQNPEKLSPI-----FRDFLNRCLEMDVEKRGSAKELLQHPFLKLAKPLSSLTPLIL 514
           +P  ++P+ L  I     F+ FL++CL+++VE R SA +LL HPFL  A  L +L PLI 
Sbjct: 38  SPLTEDPKSLHGIQRRLIFKTFLDKCLQVEVESRSSAVDLLTHPFLTKALELRTLGPLIR 217

Query: 515 AAKEAM 520
           AAK  +
Sbjct: 218 AAKREL 235

 Score = 42.0 bits (97), Expect = 6e-04,   Method: Composition-based stats.
 Identities = 19/37 (51%), Positives = 27/37 (72%)
 Frame = +1

Query: 443 YLNENPLRALYLIATNGTPELQNPEKLSPIFRDFLNR 479
           YL+E PLRALYLIA++G PE+ + +  SP  +DF  +
Sbjct: 1   YLHEAPLRALYLIASHGRPEITSWDSTSPDLQDFFRQ 111
>28638
          Length = 1458

 Score = 54.7 bits (130), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 31/92 (33%), Positives = 51/92 (55%), Gaps = 4/92 (4%)
 Frame = -1

Query: 355 ALEFLHANQ--VIHRDIKSDNVLLG--MEGSVKLTDFGFCAQITPEQSKRSTMVGTPYWM 410
           AL FL   +  +IH D+K +N+LL      ++K+ DFG   Q+     +    + + ++ 
Sbjct: 801 ALLFLATPEMNIIHCDLKPENILLCNPKRSAIKIVDFGSSCQL---GQRIYQYIQSRFYR 631

Query: 411 APEVVTRKAYGPKVDIWSLGIMAIEMVEGEPP 442
           +PEV+    Y   +D+WSLG + +EM  GEPP
Sbjct: 630 SPEVLLGVPYDLAIDMWSLGCILVEMHTGEPP 535
>00486
          Length = 797

 Score = 53.5 bits (127), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 22/46 (47%), Positives = 30/46 (65%)
 Frame = -2

Query: 402 TMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNEN 447
           T  GT  +MAPE++TR  +G  VD WSLG +  +M+ G PP+  EN
Sbjct: 781 TFCGTIEYMAPEILTRTGHGKAVDWWSLGALMYDMLTGSPPFTAEN 644
>12672
          Length = 773

 Score = 53.1 bits (126), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 36/166 (21%), Positives = 77/166 (46%), Gaps = 19/166 (11%)
 Frame = +3

Query: 348 VCRECLQALEFLHANQVIHRDIKSDNVLLGMEGSVKLTDFGFCAQITPEQSKR----STM 403
           + +     +++L+ N  +HRDIK+ N+LL  E + K+ DF         + K     S +
Sbjct: 6   IVKGTASGIQYLNDNGHVHRDIKTANILLDSEYTAKVGDFATVVSAPSGEGKTVQNASVV 185

Query: 404 VGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPEL 463
           +GT  ++APE +       K+D +S G++ +E++ G    + ++  R    ++++    +
Sbjct: 186 IGTAAYLAPEAIHFDV-STKLDSYSFGVVLLEVITG---LVAQDYSREERTLSSHIMENV 353

Query: 464 QNPEKLSPI---------------FRDFLNRCLEMDVEKRGSAKEL 494
           + PE++                    D   RCL +  ++R + K++
Sbjct: 354 EEPEEIHDFVDQSAGTWPDGAVDKLYDISMRCLNLSKKQRPNVKDI 491
>14477
          Length = 493

 Score = 50.8 bits (120), Expect = 1e-06,   Method: Composition-based stats.
 Identities = 44/166 (26%), Positives = 78/166 (46%), Gaps = 6/166 (3%)
 Frame = -1

Query: 254 KIGQGASGTVFTATDVALGQEVAI-----KQINLQKQPKKELIINEILVMKELKNPNIVN 308
           K+G G  G+V         +E+ +     K  +L    + ELI  E  VMK++ + +IV 
Sbjct: 469 KLGAGNFGSVMKGVCRLDDREIPVAIKVLKNADLDPSVQSELI-KEAEVMKKMDHMHIVR 293

Query: 309 FLDSYLVGDELFVVMEYLAGGSLTDVVTET-CMDEAQIAAVCRECLQALEFLHANQVIHR 367
            +     G+ + +V+E    G L   + +   +    I  +  +  Q +E+L AN+ +HR
Sbjct: 292 LI-GLCEGETMMLVLELAKLGPLNKFLPKNKHLPLWNILELMWQVSQGMEYLEANKFVHR 116

Query: 368 DIKSDNVLLGMEGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPE 413
           D+ + N+LL  E   K++DFG    ++ E +         Y+MA E
Sbjct: 115 DLAARNILLCDEHFAKISDFGMSKTLSRENN---------YYMAQE 5
>11185
          Length = 473

 Score = 50.1 bits (118), Expect = 2e-06,   Method: Composition-based stats.
 Identities = 41/169 (24%), Positives = 62/169 (36%), Gaps = 22/169 (13%)
 Frame = +1

Query: 353 LQALEFLHANQVIHRDIKSDNVLLGMEGSVKLTDFGFCA--------------------- 391
           +  L ++H+  ++  D++   VLL   G +K  DFG                        
Sbjct: 31  VTGLHYIHSLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEAGDQWN 210

Query: 392 -QITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLR 450
            Q   E  K+    G+P +MAPEV          D+W+LG +  EM  G    L+  P  
Sbjct: 211 IQSAEEMMKQVPTSGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFSGS--RLSAKP-- 378

Query: 451 ALYLIATNGTPELQNPEKLSPIFRDFLNRCLEMDVEKRGSAKELLQHPF 499
                              SP F + L   L+ D  +R S   L++H F
Sbjct: 379 -------------------SPEFLNLLESLLQKDSTRRLSWASLVKHAF 468
>17253
          Length = 483

 Score = 49.7 bits (117), Expect = 3e-06,   Method: Composition-based stats.
 Identities = 34/134 (25%), Positives = 63/134 (47%), Gaps = 15/134 (11%)
 Frame = -1

Query: 275 VAIKQIN-LQKQPKKELIINEILVMKEL-KNPNIVNFLDSYLVGDELFVVMEYLAGGSLT 332
           VA+K  N      +K   + E+ +M++L ++PN+V+F+    + D   ++ME+   G L 
Sbjct: 459 VAVKTHNEAATDAEKSEFLRELSIMRKLPRHPNVVSFMGCCTMSDPALILMEFCCHGDLL 280

Query: 333 DVVTETCMDEAQIAAVCRECLQALEF----LHA---------NQVIHRDIKSDNVLLGME 379
             + +   D           L A +F    LH          N+++HRD+ + NVL+   
Sbjct: 279 SFLRKRRPDRTVFLTSTANDLTARDFFSFALHVARGMAHVANNKIVHRDVAARNVLISER 100

Query: 380 GSVKLTDFGFCAQI 393
              K++DFG   ++
Sbjct: 99  NVCKVSDFGLSRRV 58
>20152
          Length = 445

 Score = 49.3 bits (116), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 32/105 (30%), Positives = 51/105 (48%), Gaps = 3/105 (2%)
 Frame = +1

Query: 412 PEVVTRKAY-GPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQNPEKLS 470
           PE++   +Y  P VD+WSLG++   +V GE P+   N    L +I        Q P  +S
Sbjct: 1   PEILLGDSYDAPAVDVWSLGVILYMLVVGEAPFQEANDSETLTMIMDC---RYQIPPHIS 171

Query: 471 PIFRDFLNRCLEMDVEKRGSAKELLQHPFLKLAK--PLSSLTPLI 513
              +D + + L+ +   R S   +L HP+L      P ++  PLI
Sbjct: 172 HKCQDLIEKMLQREPVDRASLPHILAHPWLNDGDLTPTTAYLPLI 306
>17300
          Length = 480

 Score = 48.9 bits (115), Expect = 5e-06,   Method: Composition-based stats.
 Identities = 28/86 (32%), Positives = 43/86 (50%), Gaps = 5/86 (5%)
 Frame = +1

Query: 365 IHRDIKSDNVLLGMEGSVKLTDFGFCAQI---TPEQSKRSTMVGTPY-WMAPEVVTRKAY 420
           +HRD+ + N+L+      K+ DFG   +I   T E +  +     P  W APE +  + +
Sbjct: 40  VHRDLAARNILVNEILVCKVADFGLSREIESDTTEGAYTTKGGKIPVRWTAPEAIAYRKF 219

Query: 421 GPKVDIWSLGIMAIE-MVEGEPPYLN 445
               D+WS G++  E M  GE PY N
Sbjct: 220 TSASDVWSFGVVMWEVMSYGERPYWN 297
>32000
          Length = 644

 Score = 48.9 bits (115), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 41/156 (26%), Positives = 68/156 (43%), Gaps = 26/156 (16%)
 Frame = -1

Query: 378 MEGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTR-KAYGPKVDIWSLGIMAIEM 436
           M   +K+ DFG            +  V T ++ APE++   + Y   VDIWSLG + +EM
Sbjct: 584 MTAKMKIADFGLARVFGLPVRTYTHEVITLWYRAPEILLGCRFYSVPVDIWSLGCIFVEM 405

Query: 437 VEGEPPYLNENPLRALY-LIATNGTPE---------------------LQNPE---KLSP 471
           +     +  ++ +  LY +  T GTP+                     L+N E    LS 
Sbjct: 404 MTRRALFPGDSEIDQLYRIFRTLGTPDEKVWPGVSKLPDYKPTFPKWPLKNLETVVSLSK 225

Query: 472 IFRDFLNRCLEMDVEKRGSAKELLQHPFLKLAKPLS 507
           +  D L R L  +  +R SA+  ++HP+    K ++
Sbjct: 224 VGLDLLKRMLTYNPNRRISARSAMRHPYFNDMKRMT 117
>28157
          Length = 400

 Score = 48.9 bits (115), Expect = 5e-06,   Method: Composition-based stats.
 Identities = 39/129 (30%), Positives = 68/129 (52%), Gaps = 8/129 (6%)
 Frame = +3

Query: 273 QEVAIKQINLQKQPKKELIINEILVMKELKNPNIVNFLDSYLVGDELFVVMEYLAGGSLT 332
           ++VA+K+I  + + +K+  + E+  +  + +PNIV    +      + +VMEY  GGSL 
Sbjct: 3   KDVAVKRI--ESEQEKKSFMQELKQLSRVSHPNIVCLYGA-CRDHPVCLVMEYAEGGSLY 173

Query: 333 DVVTETCMDEAQIAAVCR----ECLQALEFLHANQ---VIHRDIKSDNVLLGMEGS-VKL 384
           +V+  +       AA       +C   +E+LH  +   +IHRD+K  N+LL   G+ +K+
Sbjct: 174 NVLHGSGPQPQYTAAHAMNWLLQCALGVEYLHGMKPKALIHRDLKPPNLLLIQCGTKLKI 353

Query: 385 TDFGFCAQI 393
            DFG    I
Sbjct: 354 CDFGTACDI 380
>27274
          Length = 396

 Score = 47.4 bits (111), Expect = 2e-05,   Method: Composition-based stats.
 Identities = 28/96 (29%), Positives = 52/96 (54%), Gaps = 8/96 (8%)
 Frame = -1

Query: 413 EVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLR-------ALYLIATNGTP-ELQ 464
           E++  + +GP VD+WSLGI+  E++ G  P+  E   R       A+Y     G+  ++ 
Sbjct: 375 ELLRGQQHGPTVDMWSLGILLHELLSGHVPFEPERGSRQMARNMMAVYAQIIRGSSRDVC 196

Query: 465 NPEKLSPIFRDFLNRCLEMDVEKRGSAKELLQHPFL 500
           +   LS    DFL R ++++  KR ++++   HP++
Sbjct: 195 DGLALSTHGADFLRRLVQLEDTKRLTSQQAFSHPWI 88
>16708
          Length = 1397

 Score = 46.2 bits (108), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 19/46 (41%), Positives = 30/46 (65%)
 Frame = -1

Query: 343  AQIAAVCRECLQALEFLHANQVIHRDIKSDNVLLGMEGSVKLTDFG 388
            A +  +  + + ALE +H   V+H D+K+DNVL+   G+ KLTD+G
Sbjct: 1094 AMVCCIAGQXVCALEHIHELGVVHMDVKADNVLVDAHGNCKLTDYG 957
>20559
          Length = 430

 Score = 45.8 bits (107), Expect = 5e-05,   Method: Composition-based stats.
 Identities = 28/69 (40%), Positives = 39/69 (56%), Gaps = 4/69 (5%)
 Frame = -2

Query: 247 KKYTRYEKIGQGASGTVFTATDVALGQEVAIKQINLQKQ----PKKELIINEILVMKELK 302
           +KY + EKIG+G  GTVF A +    + VA+K++ L       P   L   EI ++KELK
Sbjct: 375 QKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSAL--REICLLKELK 202

Query: 303 NPNIVNFLD 311
           + NIV   D
Sbjct: 201 HRNIVRLHD 175
>06358
          Length = 1517

 Score = 45.4 bits (106), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 69/299 (23%), Positives = 128/299 (42%), Gaps = 46/299 (15%)
 Frame = +3

Query: 249 YTRYEKIGQGASGTVFTATDVALGQEVAI-----KQINLQKQPKKELIINEILV----MK 299
           Y +    G G    VF A+  +  +E ++     K ++   +  +E I+  + V    + 
Sbjct: 12  YNQVASAGPGLLWKVFAASKKSTKEEASVFVFEKKSVDRYSRRDREAIVEVLRVGVQQLT 191

Query: 300 ELKNPNIVNFLDSYLVGDELFV-----VMEYLAG--GSLTDVVT------ETCMDEAQIA 346
           +L++P I+  ++      E        V   LA   G L+ + T      +  + + +I 
Sbjct: 192 KLRHPKILAVINPLEESRETLAFATEPVFASLANVLGDLSSIXTVPKELQDYQLYDVEIK 371

Query: 347 AVCRECLQALEFLHAN-QVIHRDIKSDNVLLGMEGSVKLTDFGFCAQITPEQSK------ 399
               +  +AL FLH + +++HR++  + ++L   GS KL  + FC + +  QS       
Sbjct: 372 HGLLQVTEALGFLHNDAKMMHRNVCPEAIMLTKLGSWKLAGYEFCVRSSDPQSTDPSYPF 551

Query: 400 ---RSTM--VGTPY--WMAPEVVTRKAYGPKVDIWSLGIMAIEMV-EGEPPYLNENPLRA 451
              RS +  V  P+  +MAPE V     G   D++SLG++   +  +G+P +     L A
Sbjct: 552 YEWRSDIAPVTQPHLDFMAPEYVLTMQCGTGSDMFSLGLLVYSVFAKGKPLFECNGELSA 731

Query: 452 LYLIATNGTPELQN---------PEKLSPIFRDFLNRCLEMDVEKRGSAKELLQHPFLK 501
                 +   EL++         PE L    RD +   L ++   R  A +L + PF +
Sbjct: 732 F----KSNAEELRHMRVSLLGVVPEDL----RDHVKLLLNIEPAVRPDAAQLSKVPFFE 884
>32957
          Length = 645

 Score = 44.7 bits (104), Expect = 8e-05,   Method: Compositional matrix adjust.
 Identities = 21/51 (41%), Positives = 31/51 (60%)
 Frame = +3

Query: 387 FGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMV 437
           F  C + +  +++  T  GT  +MAPEV  RK YG +VD W LGI+  E++
Sbjct: 3   FALCVEKSGGRTR--TFCGTREYMAPEVHERKEYGKEVDWWGLGILLHELL 149
>01106
          Length = 878

 Score = 44.3 bits (103), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 35/148 (23%), Positives = 72/148 (48%), Gaps = 16/148 (10%)
 Frame = +3

Query: 248 KYTRYEKIGQGASGTVFTATDVALGQEVAIKQINLQKQPKKELIINEILVMKELKNPNI- 306
           +Y    K+G G   TV+   D+   + VA+K +    Q   E  ++E+ ++K ++  ++ 
Sbjct: 321 RYHVIRKLGWGHFSTVWLCWDLTCKRFVALKVVK-SAQHYTETALDEVKLLKCVRESDVA 497

Query: 307 -------VNFLDSYLV----GDELFVVMEYLAGGSLTDVVTETCMDE---AQIAAVCREC 352
                  V  LD + +    G  + +V E L G +L  ++  +         +  + R+ 
Sbjct: 498 DPARAKCVQLLDDFKISGVNGTHVAMVFEVL-GYNLLKLIIRSNYQGIPIHNVKLIIRQV 674

Query: 353 LQALEFLHAN-QVIHRDIKSDNVLLGME 379
           L+ L ++HA  ++IH DIK +N+L+ ++
Sbjct: 675 LEGLSYMHAKCRIIHTDIKPENILICVD 758
>20640
          Length = 1492

 Score = 43.9 bits (102), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 29/121 (23%), Positives = 50/121 (41%), Gaps = 3/121 (2%)
 Frame = +1

Query: 365 IHRDIKSDNVLLGMEGSVKLTDFGFCAQITPEQSKR-STMVGTPY-WMAPEVVTRKAYGP 422
           +HRD+ + N L+G +  VK++DFG    +      R S     P  WM  E +    +  
Sbjct: 10  VHRDLATRNCLVGHDLVVKISDFGLARSVHSVDYYRGSEHDAIPIRWMPLEAILYNKFST 189

Query: 423 KVDIWSLGIMAIEMVE-GEPPYLNENPLRALYLIATNGTPELQNPEKLSPIFRDFLNRCL 481
           + D+WS G++  E+      PY        +  +       L  PE+  P   + + +C 
Sbjct: 190 QSDVWSFGVVLWEIFAFALQPYYGLTHEEVVRFVKEGKV--LACPERTPPPMYELMKQCW 363

Query: 482 E 482
            
Sbjct: 364 H 366
>32691
          Length = 295

 Score = 43.5 bits (101), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 22/51 (43%), Positives = 31/51 (60%)
 Frame = +1

Query: 468 KLSPIFRDFLNRCLEMDVEKRGSAKELLQHPFLKLAKPLSSLTPLILAAKE 518
           K S  F DF+++CL  + E R +A +LLQH F+K A+    L  +I  AKE
Sbjct: 82  KWSTEFIDFVSKCLVKNPENRATAVDLLQHDFIKKAEACEILQAMIREAKE 234
>00394
          Length = 548

 Score = 43.5 bits (101), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 28/95 (29%), Positives = 51/95 (53%), Gaps = 8/95 (8%)
 Frame = -2

Query: 245 PKKKYTRYEK-IGQGASGTVFTATDVALGQEVAIKQINLQKQPK--KELIINEILVMKEL 301
           P  ++ +++K IG+G+  TV+   D  LG  VA  ++  +K  K  ++    E  ++KEL
Sbjct: 307 PDNRFLKFDKEIGRGSFKTVYKGLDTELGVAVAWCELQDKKWNKAERQRFKEEAEMLKEL 128

Query: 302 KNPNIVNFLDSYLVGDE-----LFVVMEYLAGGSL 331
           ++PNIV F D +   +      + +V E +  G+L
Sbjct: 127 QHPNIVRFFDYWEEHNHRNRKVIILVTELMTSGTL 23
>31789
          Length = 676

 Score = 42.7 bits (99), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 31/121 (25%), Positives = 61/121 (50%), Gaps = 9/121 (7%)
 Frame = +2

Query: 245 PKKKYTRYE-KIGQGASGTVFTATDVALGQEVAIKQINLQKQPK--KELIINEILVMKEL 301
           P  ++ +++ +IG+G+  TV+   D  LG  VA  ++  +K  K  ++    E  ++KEL
Sbjct: 311 PDNRFLKFDVEIGRGSFKTVYKGLDTELGVAVAWCELQDKKWNKTERQRFKEEAEMLKEL 490

Query: 302 KNPNIVNFLDSYLVGDE-----LFVVMEYLAGGSLTDVVTE-TCMDEAQIAAVCRECLQA 355
           ++PNIV F D +   +      + +V E +  G+L   +     ++   +   CR+ L+ 
Sbjct: 491 QHPNIVRFFDYWEEHNHRNRKVIILVTELMTSGTLKTYLKRFKKINLKVLKNWCRQILKG 670

Query: 356 L 356
           L
Sbjct: 671 L 673
>36481
          Length = 806

 Score = 41.2 bits (95), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 36/130 (27%), Positives = 63/130 (48%), Gaps = 9/130 (6%)
 Frame = +2

Query: 256 GQGASGTVFTATDVALGQEVAIKQI-NLQK-QPKKELIINEILVMKELKNPN----IVNF 309
           G+G  G V    D+  G ++A+K I N+ K +   +L IN +  ++E K+P+     V  
Sbjct: 389 GEGTFGKVVQCKDLLKGDDIALKIIKNVDKYREAAKLEINVLEKLRE-KDPHAKHMCVQM 565

Query: 310 LDSYLVGDELFVVMEYLAGGSLTDVVTETCMDEA---QIAAVCRECLQALEFLHANQVIH 366
           LD +     + +    L G S+ D + +         Q+  +  +   A+ FLH NQ+ H
Sbjct: 566 LDWFDYHGHVCISFHML-GLSVFDFLKDNSYGAYPIEQVRHISYQLCYAVNFLHENQLTH 742

Query: 367 RDIKSDNVLL 376
            D+K +N+L 
Sbjct: 743 TDLKPENILF 772
>07833
          Length = 1504

 Score = 41.2 bits (95), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 33/154 (21%), Positives = 72/154 (46%), Gaps = 8/154 (5%)
 Frame = -3

Query: 298  MKELKNPNIVNFLDSYLVGDELFVVMEYLAGGSLTDVV---TETCMDEAQIAAVCRECLQ 354
            ++   +PN++  L        L ++ +++  GSL + +   +   +D+ Q      +  +
Sbjct: 1457 LRIFNHPNVLPVLACCNQPPNLVLISQFMPFGSLYNTLHGESGIVVDQNQSLRFAMDIAR 1278

Query: 355  ALEFLHANQ--VIHRDIKSDNVLLGMEGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAP 412
             +EFLH+ +  + +  + S +V++  + + ++    +C     E+ K    V +P WMAP
Sbjct: 1277 GMEFLHSMEPTIPNFLLTSKHVMIDEDLTARINMADYCFSFH-EKGK----VYSPAWMAP 1113

Query: 413  EVVTRK---AYGPKVDIWSLGIMAIEMVEGEPPY 443
            E + R+         D+WS  I+  E+   E P+
Sbjct: 1112 EALQRRPDDINTRAADMWSFAILMWELETREVPF 1011
>26009
          Length = 886

 Score = 40.0 bits (92), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 17/49 (34%), Positives = 29/49 (59%)
 Frame = +3

Query: 328 GGSLTDVVTETCMDEAQIAAVCRECLQALEFLHANQVIHRDIKSDNVLL 376
           G  LT           +  +V ++ + AL+F+H+ Q++HRDIK +NVL+
Sbjct: 666 GTCLTPSRRNKACGSREAKSVMKQLVSALDFMHSKQLVHRDIKPENVLI 812
>18996
          Length = 491

 Score = 39.7 bits (91), Expect = 0.003,   Method: Composition-based stats.
 Identities = 28/87 (32%), Positives = 41/87 (47%), Gaps = 7/87 (8%)
 Frame = +2

Query: 365 IHRDIKSDNVLLGMEGSVKLTDFGFCAQITPEQ------SKRSTMVGTPYWMAPEVVTRK 418
           IHRD+ + N+L+     VK++DFG  AQ           S+R   +    W +PE +   
Sbjct: 2   IHRDLAARNILVD-RSCVKISDFGL-AQFANADGYYYGISQRDIPIK---WYSPEAIETC 166

Query: 419 AYGPKVDIWSLGIMAIEMV-EGEPPYL 444
            +    D+WS G+   EM   GE P L
Sbjct: 167 KFSSYSDVWSYGVTLFEMFSRGEIPNL 247
>29590
          Length = 320

 Score = 39.3 bits (90), Expect = 0.004,   Method: Composition-based stats.
 Identities = 18/59 (30%), Positives = 33/59 (55%)
 Frame = +3

Query: 386 DFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYL 444
           D GF       +  R  ++GTP ++APEV+  +    + D+WSLG+++  M+    P++
Sbjct: 6   DLGFACLTNTGEDIRD-IIGTPDYVAPEVLDYEPLSIQTDMWSLGVLSYVMLTACSPFV 179
>31489
          Length = 329

 Score = 38.9 bits (89), Expect = 0.006,   Method: Composition-based stats.
 Identities = 22/87 (25%), Positives = 44/87 (50%), Gaps = 6/87 (6%)
 Frame = +3

Query: 295 ILVMKELKNPNIVNFL------DSYLVGDELFVVMEYLAGGSLTDVVTETCMDEAQIAAV 348
           I ++K  K+ NI++        DSY    ++ VV + +       + ++  + E  I   
Sbjct: 3   IKILKHFKHDNIISIREILKPKDSYHDFKDIHVVFDLMESDLHRIIYSDQPLTEEHIRYF 182

Query: 349 CRECLQALEFLHANQVIHRDIKSDNVL 375
             + L+ L+++H+  V+HRD+K  N+L
Sbjct: 183 LYQILRGLKYIHSANVVHRDLKPSNLL 263
>18481
          Length = 437

 Score = 38.1 bits (87), Expect = 0.008,   Method: Composition-based stats.
 Identities = 28/82 (34%), Positives = 40/82 (48%), Gaps = 5/82 (6%)
 Frame = -1

Query: 321 VVMEYLAGGSLTD--VVTETCMDEAQIAAVCRECLQALEFLHANQVIHRDIKSDNVLLGM 378
           +VME L G SL +  V+ +       I  V  + L  LEF+H    IHRD+K DN L+G+
Sbjct: 266 LVMELL-GPSLEELFVICKRRFTLKTILMVSDQLLSRLEFIHQKCFIHRDLKPDNFLMGL 90

Query: 379 E---GSVKLTDFGFCAQITPEQ 397
                 + + DFG   +    Q
Sbjct: 89  GRHCHRLYIIDFGLSKRYKDTQ 24
>17516
          Length = 453

 Score = 38.1 bits (87), Expect = 0.010,   Method: Composition-based stats.
 Identities = 18/40 (45%), Positives = 27/40 (67%), Gaps = 1/40 (2%)
 Frame = -3

Query: 402 TMVGTPYWMAPEVVTRKA-YGPKVDIWSLGIMAIEMVEGE 440
           T+ GTP +MAPEV+ +K  Y  K D++SL I+  E+  G+
Sbjct: 442 TLAGTPVYMAPEVLLQKGQYDMKADVYSLAIILWELWYGQ 323
>16350
          Length = 1108

 Score = 37.4 bits (85), Expect = 0.013,   Method: Compositional matrix adjust.
 Identities = 17/30 (56%), Positives = 21/30 (70%)
 Frame = +3

Query: 473 FRDFLNRCLEMDVEKRGSAKELLQHPFLKL 502
           F DFL   LE D E+R +A + LQHP+LKL
Sbjct: 756 FADFLAPMLEFDPEQRATAAQSLQHPWLKL 845

 Score = 30.8 bits (68), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 16/43 (37%), Positives = 21/43 (48%)
 Frame = +2

Query: 404 VGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNE 446
           + T  +   EV+    YG   DIWS   MA E+  G+  YL E
Sbjct: 413 IQTRQYRCLEVLIGAGYGTPADIWSTACMAFELATGD--YLFE 535
>20513
          Length = 405

 Score = 37.0 bits (84), Expect = 0.017,   Method: Compositional matrix adjust.
 Identities = 26/54 (48%), Positives = 31/54 (57%), Gaps = 2/54 (3%)
 Frame = -1

Query: 473 FRDFLNRCLEMDVEKRGSAKELLQHPFLKL-AKPL-SSLTPLILAAKEAMKSNR 524
           F DFL   LE D E+R +A + LQHP+LKL A P  S    LI   KE+M   R
Sbjct: 288 FADFLAPMLEFDPEQRATAAQSLQHPWLKLDA*PEPSGSQQLICLFKESMIGQR 127
>18401
          Length = 463

 Score = 35.0 bits (79), Expect = 0.076,   Method: Composition-based stats.
 Identities = 35/142 (24%), Positives = 54/142 (38%), Gaps = 42/142 (29%)
 Frame = -3

Query: 401 STMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEG----------EPPYLNENPLR 450
           ST+V T ++ APEV+    +    D+WS+G +  E+  G          E   + E  L 
Sbjct: 458 STIVSTRHYRAPEVILELGWSHPCDVWSVGCIMFELYTGYTLFQTHDNKEHLAMMERILG 279

Query: 451 AL-YLIATNGTPE-------LQNPEKLS----------PIFR--------------DFLN 478
           +L Y +A     +       L  PE+ S          P+ R              D + 
Sbjct: 278 SLPYRMAKKTKKQKYFHHGRLDVPERSSMARYVRENTKPLLRYVKDRENKDHQQLFDLMK 99

Query: 479 RCLEMDVEKRGSAKELLQHPFL 500
           + L  +   R S  + LQHPF 
Sbjct: 98  KLLAYEASSRYSLLQALQHPFF 33
>14104
          Length = 573

 Score = 33.5 bits (75), Expect = 0.22,   Method: Compositional matrix adjust.
 Identities = 13/33 (39%), Positives = 21/33 (63%)
 Frame = +1

Query: 470 SPIFRDFLNRCLEMDVEKRGSAKELLQHPFLKL 502
           +P    F+  CL+MD  +R +  +LLQHP++ L
Sbjct: 91  APQAMSFMQSCLKMDPAERLTCHQLLQHPYMDL 189
>23319
          Length = 2235

 Score = 33.5 bits (75), Expect = 0.23,   Method: Compositional matrix adjust.
 Identities = 32/124 (25%), Positives = 49/124 (39%), Gaps = 29/124 (23%)
 Frame = +3

Query: 412 PEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYL----NENPLRALYLIATNGTP-ELQNP 466
           P+V   K Y   +D+WS G +  E+     P      +++ L+ ++ +   GTP E Q P
Sbjct: 3   PDVYXAKMYSTSIDMWSAGCIFAELANAGRPLFPGNDDDDQLKRIFKLL--GTPTEDQWP 176

Query: 467 -------EKLSPIF-----------------RDFLNRCLEMDVEKRGSAKELLQHPFLKL 502
                   ++ P++                 RD L   L      R SA E LQHP+   
Sbjct: 177 GMTQLPNYRMFPMYHVTTTWQQVVPKLNSKGRDLLQCLLVCCPSDRMSADEALQHPYFAD 356

Query: 503 AKPL 506
             PL
Sbjct: 357 LPPL 368
>11404
          Length = 563

 Score = 33.1 bits (74), Expect = 0.27,   Method: Compositional matrix adjust.
 Identities = 40/139 (28%), Positives = 65/139 (46%), Gaps = 13/139 (9%)
 Frame = +1

Query: 251 RYE---KIGQGASGTVFTATDVALGQEVAIKQINLQK----QPKKELIINEILVMKELKN 303
           RYE    IG+G+ G V  A D    ++VAIK I  +K    Q + E+ + E++   +  N
Sbjct: 142 RYEIDSLIGKGSFGQVVKAYDHTDNEQVAIKIIKNKKPFLNQAQIEVKLLEMMNRHDTDN 321

Query: 304 P-NIVNFLDSYLVGDELFVVMEYLAGGSLTDVVTETCMDEAQI---AAVCRECLQALEFL 359
              IV     ++    L +V E L+  +L D++  T      +       ++   AL FL
Sbjct: 322 KYYIVRLKRHFMFRSHLCLVFELLS-YNLYDLLRNTNFRGVSLNLTRKFAQQLCTALLFL 498

Query: 360 HA--NQVIHRDIKSDNVLL 376
                 +IH D+K +N+LL
Sbjct: 499 ATPEMSIIHCDLKPENILL 555
>03294
          Length = 1684

 Score = 33.1 bits (74), Expect = 0.29,   Method: Compositional matrix adjust.
 Identities = 26/103 (25%), Positives = 42/103 (40%), Gaps = 26/103 (25%)
 Frame = -1

Query: 424  VDIWSLGIMAIEMVEGEPPYLNENPLRALYLI-------------------ATNGTPELQ 464
            VD+WS+G +  +M+   P +  ++ +  L+ I                   A NG   L 
Sbjct: 1672 VDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIFRIIGTPTEQTWPEFHKLPAFNGMFPLW 1493

Query: 465  NPEKLSPIFR-------DFLNRCLEMDVEKRGSAKELLQHPFL 500
               KLS           D + R L+ D  +R S K++LQH + 
Sbjct: 1492 KEGKLSETLTDLDSLGLDLIERTLKCDPAQRISCKKMLQHAYF 1364
>17637
          Length = 447

 Score = 32.3 bits (72), Expect = 0.51,   Method: Composition-based stats.
 Identities = 13/41 (31%), Positives = 22/41 (53%), Gaps = 1/41 (2%)
 Frame = +1

Query: 409 WMAPEVVTRKAYGPKVDIWSLGIMAIEMVE-GEPPYLNENP 448
           W++ E + +  Y    D+WS G++  EM   G+ PY   +P
Sbjct: 115 WLSLEALQKSHYNEGSDVWSFGVLMWEMCTLGKLPYAEIDP 237
>21800
          Length = 855

 Score = 31.2 bits (69), Expect = 1.0,   Method: Compositional matrix adjust.
 Identities = 27/110 (24%), Positives = 51/110 (46%), Gaps = 15/110 (13%)
 Frame = +2

Query: 285 QPKKELIINEILVMKELKNPN--------IVNFLDSYLV----GDELFVVMEYLAGGSLT 332
           Q   E  ++EI ++K ++N +         V  LD + +    G  + +V E L    L 
Sbjct: 416 QHYTETALDEIKLLKCVRNSDETDPAREKSVQLLDDFKISGVNGTHVCMVFEVLGYNLLK 595

Query: 333 DVVTETCMD--EAQIAAVCRECLQALEFLHAN-QVIHRDIKSDNVLLGME 379
            ++           +  + R+ L+ L +LHA   +IH DIK +N+L+ ++
Sbjct: 596 LIIRSNYQGIPVHNVKLIIRQVLEGLNYLHAKCNIIHTDIKPENILICVD 745
>37063
          Length = 455

 Score = 31.2 bits (69), Expect = 1.1,   Method: Composition-based stats.
 Identities = 23/64 (35%), Positives = 32/64 (50%), Gaps = 13/64 (20%)
 Frame = -2

Query: 382 VKLTDFGFCAQI--------TPEQSKRSTMVGTPYWMAPEVV-----TRKAYGPKVDIWS 428
           +K+ DF   + I        TPE     T VG+  +MAPEVV        +Y  + D+WS
Sbjct: 406 LKICDFDLASGINCDGDGTKTPELL---TPVGSAEYMAPEVVDAWVGESFSYDKRCDMWS 236

Query: 429 LGIM 432
           LGI+
Sbjct: 235 LGII 224
>13305
          Length = 549

 Score = 30.8 bits (68), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 13/36 (36%), Positives = 19/36 (52%), Gaps = 1/36 (2%)
 Frame = +2

Query: 409 WMAPEVVTRKAYGPKVDIWSLGIMAIEMVE-GEPPY 443
           WMA E +    Y  + D+WS G++  E+   G  PY
Sbjct: 23  WMAVESLFNNTYTTQSDVWSFGVVLWEIFTLGGTPY 130
>31120
          Length = 439

 Score = 30.0 bits (66), Expect = 2.3,   Method: Composition-based stats.
 Identities = 15/36 (41%), Positives = 22/36 (61%), Gaps = 1/36 (2%)
 Frame = +1

Query: 413 EVVTRKAYGPKV-DIWSLGIMAIEMVEGEPPYLNEN 447
           EVV    Y PK+ D WSLG++   M+ G+ P+ + N
Sbjct: 1   EVVCGVPYDPKMADAWSLGVILFIMLNGKMPFDDSN 108
>22005
          Length = 873

 Score = 29.6 bits (65), Expect = 3.1,   Method: Compositional matrix adjust.
 Identities = 48/244 (19%), Positives = 87/244 (35%), Gaps = 61/244 (25%)
 Frame = +1

Query: 255 IGQGASGTV----FTATDVALGQEVAIKQ-----INLQKQPKKEL---IINEILVMKELK 302
           IGQGA G V    F      +G+ +  K+       L++   ++L      E  +M +  
Sbjct: 7   IGQGAFGRVSKLKFLGLASLVGELIPEKRP*LL*KMLKEDASEDLQSDFEREASLMADFD 186

Query: 303 NPNIVNFLDSYLVGDELFVVMEYLAGGSLTD----------------------------- 333
           +PNIV  L    +G  + ++ E+++ G L D                             
Sbjct: 187 HPNIVKLLGVCAIGKPMCLLFEFMSKGDLNDFLRLCSPENYNLPVSRSQNLVVDLEDGLR 366

Query: 334 --VVTETCMDEAQIAAVCRECLQALE----------------FLHANQVIHRDIKSDNVL 375
             V  E C  + Q     R+C   L                 +L     +HRD+ +   +
Sbjct: 367 VEVEAEECEKDTQSED--RDCSGMLXTKDQLYISQQISAGMAYLAQKDYVHRDL-ATRTV 537

Query: 376 LGMEGSVKLTDFGFCAQI-TPEQSKRSTMVGTPY-WMAPEVVTRKAYGPKVDIWSLGIMA 433
                   ++DFG    + + +  + S     P  WM  E +    +  + D+WS G++ 
Sbjct: 538 XSRTT*S*ISDFGLARSVHSVDYYRGSEQDAIPIRWMPLEAILYSKFSTQSDVWSFGVVL 717

Query: 434 IEMV 437
            E++
Sbjct: 718 WEIL 729
>01970
          Length = 2861

 Score = 28.1 bits (61), Expect = 8.0,   Method: Compositional matrix adjust.
 Identities = 16/60 (26%), Positives = 27/60 (45%), Gaps = 1/60 (1%)
 Frame = -1

Query: 366  HRDIKSDNVLLGMEGSVKLTDFGF-CAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKV 424
            +RD  +D V +    ++K  + G  CA ITP++ +         W++P    R   G  V
Sbjct: 2735 YRDQTNDQVTIDSAEAIKKYNVGIKCATITPDEERVEEFKLKKMWLSPNGTIRNILGGTV 2556
>28068
          Length = 450

 Score = 28.1 bits (61), Expect = 8.9,   Method: Compositional matrix adjust.
 Identities = 14/27 (51%), Positives = 19/27 (70%)
 Frame = -3

Query: 1   MSDNGELEDKPPAPPVRMSSTIFSTGG 27
           +S++GE   KPPAPPVR++ST     G
Sbjct: 289 LSEDGE---KPPAPPVRLASTRMVNQG 218
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|165377181|ref|NP_598912.3| tyrosyl-tRNA synthetase
[Mus musculus]
         (528 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

32464                                                                 333   1e-91
17358                                                                 171   3e-57
12674                                                                 171   9e-43
33013                                                                 122   3e-28
36599                                                                  39   0.004
18275                                                                  39   0.005
00180                                                                  28   9.5  
>32464
          Length = 634

 Score =  333 bits (853), Expect = 1e-91,   Method: Compositional matrix adjust.
 Identities = 160/209 (76%), Positives = 174/209 (83%)
 Frame = +2

Query: 64  KAGCEVTILFADLHAYLDNMKAPWELLELRTSYYENVIKAMLESIGVPLEKLKFIKGTDY 123
           +AGCEVT+LFADLHAYLDNMKAPW+LLE R  YYE VIKAML SI VPL+KL F+KGTDY
Sbjct: 2   RAGCEVTVLFADLHAYLDNMKAPWQLLEQRVKYYECVIKAMLRSINVPLDKLHFVKGTDY 181

Query: 124 QLSKEYTLDVYRLSSVVTQHDAKKAGAEVVKQVEHPLLSGLLYPGLQALDEEYLKVDAQF 183
           QLS EYT DVYRLS++VT+HDAKKAGAEVVKQV HPLLSGL+YPGLQALDEEYLKVDAQF
Sbjct: 182 QLSNEYTRDVYRLSTMVTKHDAKKAGAEVVKQVSHPLLSGLIYPGLQALDEEYLKVDAQF 361

Query: 184 GGVDQRKIFTFAEKYLPALGYSKRVHLMNPMVPGLTGSKMXXXXXXXKIXXXXXXXXXXX 243
           GGVDQRKIFTFAEKY+  +GYSKR+HLMNPMVPGLTGSKM       KI           
Sbjct: 362 GGVDQRKIFTFAEKYMTRMGYSKRIHLMNPMVPGLTGSKMSSSEEDSKIDLLDSPXQLKK 541

Query: 244 XXXXAFCEPGNVENNGVLSFIKHVLFPLK 272
               A CEPGNVE+NGVLSF KHVLFPL+
Sbjct: 542 KLSNAXCEPGNVEDNGVLSFCKHVLFPLR 628
>17358
          Length = 635

 Score =  171 bits (434), Expect(2) = 3e-57,   Method: Compositional matrix adjust.
 Identities = 83/122 (68%), Positives = 101/122 (82%)
 Frame = +2

Query: 361 EEVIPSRLDIRVGKILSVEKHPDADSLYVEKIDVGEAEPRTVVSGLVQFVPKEELQDRLV 420
           +EV P+RLD+RVGKI SV+KHP+ADSLY+E +D+GE   RTV+SGL   VP EELQDRL 
Sbjct: 272 DEVSPARLDLRVGKITSVKKHPEADSLYIESVDLGEESERTVISGLAGLVPMEELQDRLG 451

Query: 421 VVLCNLKPQKMRGVDSQGMLLCASVEGVSRQVEPLDPPAGSAPGERVFVQGYEKGQPDEE 480
           V LCNLKP KMRG++S GML+CASV+   R VEPL+PP GS+PG+RVFV+GYEKG PDE+
Sbjct: 452 VFLCNLKPVKMRGIESCGMLMCASVDD-PRAVEPLNPPEGSSPGDRVFVEGYEKGTPDEK 628

Query: 481 LK 482
           L 
Sbjct: 629 LN 634

 Score = 69.3 bits (168), Expect(2) = 3e-57,   Method: Compositional matrix adjust.
 Identities = 36/77 (46%), Positives = 50/77 (64%)
 Frame = +3

Query: 273 SEFVILRDEKWGGNKTYTVYLELEKDFAAEVVHPGDLKNSVEVALNKLLDPIREKFNTPA 332
           + F + R  + GG+  +  Y ELEK FA   +HP DLK++VE  LN LL P+RE+F++P 
Sbjct: 9   NHFTVKRSPENGGDIRFNSYDELEKAFANMELHPADLKSAVEAYLNCLLKPVREQFDSPD 188

Query: 333 LKKLASAAYPDPSKQKP 349
           +K L S AYP   K+KP
Sbjct: 189 MKTLVSKAYP-VQKKKP 236
>12674
          Length = 829

 Score =  171 bits (432), Expect = 9e-43,   Method: Compositional matrix adjust.
 Identities = 88/175 (50%), Positives = 120/175 (68%), Gaps = 1/175 (0%)
 Frame = -2

Query: 355 AKNSEPEEVIPSRLDIRVGKILSVEKHPDADSLYVEKIDVGEAEPRTVVSGLVQFVPKEE 414
           A  +EPE++  SRLD R+GKI +VEKHPDAD+LYVE +D+GE +PRT+VSGLV  +P E+
Sbjct: 630 AGAAEPEKMDVSRLDFRIGKITAVEKHPDADTLYVETVDLGEEKPRTIVSGLVNHIPIEQ 451

Query: 415 LQDRLVVVLCNLKPQKMRGVDSQGMLLCASVEGVSRQVEPLDPPAGSAPGERVFVQGYEK 474
           +Q+RL V +CNLK  KMRGV S+GM++CA  E    +VE L+PP G  PG+R+   GY  
Sbjct: 450 MQNRLAVFMCNLKASKMRGVSSEGMIMCAKNE----KVEILEPPPGVVPGDRITFDGY-P 286

Query: 475 GQPDEELKPKKKVFEKLQADFKISEECIAQWKQTNFMTK-LGFVSCKSLKGGNIS 528
           G PD++L PKKKV+E L+ D + + E +A +K   F  +  G V   +L    IS
Sbjct: 285 GTPDKQLNPKKKVWETLKPDIRTNGERVATFKGAPFKVEGKGIVKAPTLTNAEIS 121
>33013
          Length = 277

 Score =  122 bits (307), Expect = 3e-28,   Method: Composition-based stats.
 Identities = 56/84 (66%), Positives = 69/84 (82%)
 Frame = -1

Query: 361 EEVIPSRLDIRVGKILSVEKHPDADSLYVEKIDVGEAEPRTVVSGLVQFVPKEELQDRLV 420
           +E  P RLDIRVGK++ V +HPDAD+LYV KID+ EA+PRT++SGLV+FV  EEL  RLV
Sbjct: 274 DEDAPHRLDIRVGKVIEVARHPDADTLYVLKIDLAEAQPRTIISGLVKFVTVEELDQRLV 95

Query: 421 VVLCNLKPQKMRGVDSQGMLLCAS 444
            VLCNLKP KMRG+ S+GM+LC S
Sbjct: 94  AVLCNLKPSKMRGIMSEGMVLCTS 23
>36599
          Length = 197

 Score = 39.3 bits (90), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 21/47 (44%), Positives = 30/47 (63%)
 Frame = -3

Query: 440 LLCASVEGVSRQVEPLDPPAGSAPGERVFVQGYEKGQPDEELKPKKK 486
           ++CA  E    +VE L+PP G  PG+R+   GY  G PD++L PK+K
Sbjct: 159 VMCAKNE----KVEILEPPPGVVPGDRITFDGYP-GTPDKQLNPKRK 34
>18275
          Length = 476

 Score = 38.9 bits (89), Expect = 0.005,   Method: Composition-based stats.
 Identities = 18/29 (62%), Positives = 23/29 (79%)
 Frame = +2

Query: 355 AKNSEPEEVIPSRLDIRVGKILSVEKHPD 383
           A  +EPE++  SRLD R+GKI +VEKHPD
Sbjct: 389 AGAAEPEKMDVSRLDFRIGKITAVEKHPD 475
>00180
          Length = 1085

 Score = 28.1 bits (61), Expect = 9.5,   Method: Compositional matrix adjust.
 Identities = 22/60 (36%), Positives = 29/60 (48%), Gaps = 2/60 (3%)
 Frame = +1

Query: 321 LDPIREKFNTPALKKLASAAYPDPSKQKPPAKGPAKNSEPEEVI--PSRLDIRVGKILSV 378
           LDPIR   NTP +KK   A  P  S + PP +GP     PE     P  +   +G  L++
Sbjct: 874 LDPIR---NTPMVKK--GAPNPPASYKNPPKRGPTTYPRPENTSKEPKTMATELGNSLAI 1038
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6680716|ref|NP_031502.1| ADP-ribosylation factor 1
[Mus musculus]
         (181 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

09827                                                                 330   2e-91
08153                                                                 312   5e-86
10862                                                                 176   5e-45
33605                                                                 106   1e-27
32860                                                                 103   1e-24
11378                                                                 105   8e-24
18208                                                                  99   1e-21
06991                                                                  74   5e-14
19506                                                                  71   3e-13
18949                                                                  69   1e-12
15662                                                                  66   7e-12
11965                                                                  48   2e-06
34468                                                                  47   4e-06
29196                                                                  42   1e-04
14775                                                                  42   2e-04
13750                                                                  41   2e-04
08428                                                                  40   6e-04
19006                                                                  38   0.002
33374                                                                  37   0.004
35581                                                                  36   0.009
33380                                                                  36   0.009
20877                                                                  36   0.010
33794                                                                  35   0.022
07465                                                                  35   0.022
26083                                                                  35   0.024
11728                                                                  33   0.061
13901                                                                  33   0.066
26536                                                                  33   0.072
17511                                                                  33   0.081
05468                                                                  31   0.36 
01972                                                                  27   3.7  
22540                                                                  27   4.1  
34359                                                                  27   4.7  
18743                                                                  26   7.3  
>09827
          Length = 1201

 Score =  330 bits (847), Expect = 2e-91,   Method: Compositional matrix adjust.
 Identities = 160/184 (86%), Positives = 169/184 (91%), Gaps = 3/184 (1%)
 Frame = -3

Query: 1    MGNIFANLFKGL---FGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVE 57
            MGN F  +F GL   FGKK+MRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVE
Sbjct: 1172 MGNAFQKIFSGLSFMFGKKDMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVE 993

Query: 58   YKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELR 117
            YKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSND+ERV EAREEL RML EDELR
Sbjct: 992  YKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDKERVQEAREELTRMLNEDELR 813

Query: 118  DAVLLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLSNQL 177
            DAVLLVFANKQDLP+AM  AEIT+KLGLH LR+R WYIQ+TCAT+GDGLYEGLDWLSNQL
Sbjct: 812  DAVLLVFANKQDLPHAMATAEITEKLGLHGLRNRTWYIQSTCATTGDGLYEGLDWLSNQL 633

Query: 178  RNQK 181
            +N K
Sbjct: 632  KNNK 621
>08153
          Length = 1703

 Score =  312 bits (799), Expect = 5e-86,   Method: Compositional matrix adjust.
 Identities = 146/176 (82%), Positives = 164/176 (93%)
 Frame = +1

Query: 5   FANLFKGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNISFT 64
           F +LFK LFGKKE+RILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNISFT
Sbjct: 46  FVSLFKNLFGKKEVRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNISFT 225

Query: 65  VWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAVLLVF 124
           VWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRER+NEA+EEL RML ED+LRDA++LVF
Sbjct: 226 VWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERINEAKEELARMLNEDDLRDAIILVF 405

Query: 125 ANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLSNQLRNQ 180
           ANKQDLPNA +A+E+T  LGL +L+ R WY+QATCATSGDG+YEGL+WLS  L+++
Sbjct: 406 ANKQDLPNAYSASEVTAHLGLANLKGRKWYMQATCATSGDGMYEGLEWLSTTLKHK 573
>10862
          Length = 2896

 Score =  176 bits (446), Expect = 5e-45,   Method: Compositional matrix adjust.
 Identities = 76/125 (60%), Positives = 97/125 (77%)
 Frame = -3

Query: 51   FNVETVEYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRM 110
                  + +   F VWDVGGQDKIRPLWRHY+  TQGLIFVVD  DR+R++EAR+EL R+
Sbjct: 2516 IQCRNCQLQECQFNVWDVGGQDKIRPLWRHYYTGTQGLIFVVDCADRDRIDEARQELHRI 2337

Query: 111  LAEDELRDAVLLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGL 170
            + + E+RDA++L+FANKQDLP+AM   EI +KLGL  LR RNWY+Q +CAT+GDGL EGL
Sbjct: 2336 INDREMRDAIILIFANKQDLPDAMKPHEIQEKLGLTRLRDRNWYVQPSCATTGDGLCEGL 2157

Query: 171  DWLSN 175
             WL++
Sbjct: 2156 TWLTS 2142

 Score = 85.9 bits (211), Expect = 8e-18,   Method: Compositional matrix adjust.
 Identities = 39/55 (70%), Positives = 48/55 (87%)
 Frame = -1

Query: 8    LFKGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNIS 62
            L   +FG KEMRILM+GLDAAGKTT+LYK+KLG+ VT IPT+GFNVETV +KN++
Sbjct: 2644 LLSKIFGNKEMRILMLGLDAAGKTTLLYKMKLGQSVTXIPTVGFNVETVSFKNVN 2480
>33605
          Length = 888

 Score =  106 bits (264), Expect(2) = 1e-27,   Method: Compositional matrix adjust.
 Identities = 47/92 (51%), Positives = 68/92 (73%)
 Frame = +1

Query: 15  KKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNISFTVWDVGGQDKI 74
           +KE+R+LM+GLD AGKTTIL K    +I T  PT+GFN++T+E++     VWDVGGQ  +
Sbjct: 490 EKEVRLLMLGLDNAGKTTILKKFNGEDIDTISPTLGFNIKTLEHRGFKLNVWDVGGQQSL 669

Query: 75  RPLWRHYFQNTQGLIFVVDSNDRERVNEAREE 106
           R  WR+YF++T GL++VVDS DR R+ + + +
Sbjct: 670 RSYWRNYFESTDGLVWVVDSADRMRIADCKRD 765

 Score = 33.1 bits (74), Expect(2) = 1e-27,   Method: Compositional matrix adjust.
 Identities = 17/41 (41%), Positives = 23/41 (56%)
 Frame = +3

Query: 107 LMRMLAEDELRDAVLLVFANKQDLPNAMNAAEITDKLGLHS 147
           L  +L E+ L  A LLVFAN +  P A+ + EI   + L S
Sbjct: 765 LQGLLVEERLAGATLLVFANSRTCPGALXSQEIQQAMDLDS 887
>32860
          Length = 330

 Score =  103 bits (258), Expect(2) = 1e-24,   Method: Compositional matrix adjust.
 Identities = 46/89 (51%), Positives = 65/89 (73%)
 Frame = +2

Query: 78  WRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAVLLVFANKQDLPNAMNAA 137
           W  Y+ N++ +I V+DS DRER++  +EEL RMLA +ELR A LLVFANKQD+   M+AA
Sbjct: 8   WNTYYSNSEFIIMVIDSTDRERLSITKEELCRMLATEELRXAALLVFANKQDIKGCMSAA 187

Query: 138 EITDKLGLHSLRHRNWYIQATCATSGDGL 166
           EI+ +L L S++   W+IQA C  +G+G+
Sbjct: 188 EISXQLNLTSVKDHVWHIQACCGLTGEGV 274

 Score = 25.4 bits (54), Expect(2) = 1e-24,   Method: Compositional matrix adjust.
 Identities = 7/16 (43%), Positives = 14/16 (87%)
 Frame = +1

Query: 165 GLYEGLDWLSNQLRNQ 180
           GLY+GL+W+++ +R +
Sbjct: 271 GLYQGLEWITSHIRRR 318
>11378
          Length = 1688

 Score =  105 bits (263), Expect = 8e-24,   Method: Compositional matrix adjust.
 Identities = 54/140 (38%), Positives = 88/140 (62%)
 Frame = +3

Query: 9   FKGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNISFTVWDV 68
           F GL+ KK  +++ +GLD AGKTT+L+ LK  ++   +PT+    E +    + FT +D+
Sbjct: 300 FLGLY-KKSGKLVFLGLDNAGKTTLLHMLKDDKMAQHVPTLHPTSEELSMGGMRFTTFDL 476

Query: 69  GGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAVLLVFANKQ 128
           GG  + R +W+ YF    G++F+VD +DRER+ EA+ EL  ++ ++++ +A +LV  NK 
Sbjct: 477 GGHRQARRVWKDYFPAVDGIVFLVDVHDRERLVEAKAELDSLMTDEQVANAPILVLGNKI 656

Query: 129 DLPNAMNAAEITDKLGLHSL 148
           D P A +  EI    GL+SL
Sbjct: 657 DKPGAASEEEIRHWFGLNSL 716
>18208
          Length = 458

 Score = 98.6 bits (244), Expect = 1e-21,   Method: Compositional matrix adjust.
 Identities = 43/88 (48%), Positives = 64/88 (72%)
 Frame = -1

Query: 16  KEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNISFTVWDVGGQDKIR 75
           +E+RIL++GLD AGKTT+L +L   +     PT GFN+++V+ K     VWD+GGQ +IR
Sbjct: 305 RELRILLLGLDNAGKTTLLKQLASEDPSHITPTQGFNIKSVQSKGFKLNVWDIGGQRRIR 126

Query: 76  PLWRHYFQNTQGLIFVVDSNDRERVNEA 103
           P W++YF+NT  LI+V+DS+D +R+ E 
Sbjct: 125 PYWKNYFENTDLLIYVIDSSDTKRMEET 42
>06991
          Length = 1860

 Score = 73.6 bits (179), Expect = 5e-14,   Method: Compositional matrix adjust.
 Identities = 33/67 (49%), Positives = 46/67 (68%)
 Frame = -2

Query: 111  LAEDELRDAVLLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGL 170
            L EDEL+ ++L+VFANKQD+  AM   E+ + LGL  L++R + I  T A  G+GL E +
Sbjct: 1859 LEEDELKKSILMVFANKQDIEGAMTVTEVANSLGLPGLKNRKYQIFKTSAVKGEGLDEAM 1680

Query: 171  DWLSNQL 177
            +WLSN L
Sbjct: 1679 EWLSNSL 1659
>19506
          Length = 421

 Score = 70.9 bits (172), Expect = 3e-13,   Method: Compositional matrix adjust.
 Identities = 34/61 (55%), Positives = 45/61 (73%)
 Frame = -3

Query: 1   MGNIFANLFKGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKN 60
           MG+    LF+    +K + ++  GLDAAGKTT+LY LKLGE+VTTIPTIGFNVET++   
Sbjct: 173 MGSALCTLFR----QKPVTVIYFGLDAAGKTTLLYNLKLGEVVTTIPTIGFNVETLDMNR 6

Query: 61  I 61
           +
Sbjct: 5   V 3
>18949
          Length = 414

 Score = 68.6 bits (166), Expect = 1e-12,   Method: Compositional matrix adjust.
 Identities = 31/83 (37%), Positives = 50/83 (60%)
 Frame = +3

Query: 47  PTIGFNVETVEYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREE 106
           PT     E +    ++FT +D+GG  + R +W+ YF    G++F+VD +D ER+ EA+ E
Sbjct: 15  PTGLPTSEELSMGGMTFTTFDLGGHRQARRVWKDYFPAVDGIVFIVDVHDTERITEAKAE 194

Query: 107 LMRMLAEDELRDAVLLVFANKQD 129
           L  +L +D++ D  +LV  NK D
Sbjct: 195 LDSLLRDDQIADIPVLVLGNKMD 263
>15662
          Length = 455

 Score = 66.2 bits (160), Expect = 7e-12,   Method: Compositional matrix adjust.
 Identities = 31/76 (40%), Positives = 48/76 (63%)
 Frame = +2

Query: 73  KIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAVLLVFANKQDLPN 132
           + R +W+ YF    G++F+VD +DRER  EA+ EL  ++ ++++ +A +LV  NK D P 
Sbjct: 2   QARRVWKDYFPAVDGIVFLVDVHDRERFVEAKAELDSLMTDEQVANAPILVLGNKIDKPG 181

Query: 133 AMNAAEITDKLGLHSL 148
           A +  EI    GLHSL
Sbjct: 182 AASEDEIRHWFGLHSL 229
>11965
          Length = 3256

 Score = 48.1 bits (113), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 29/97 (29%), Positives = 49/97 (50%), Gaps = 10/97 (10%)
 Frame = +1

Query: 44  TTIPTIGFNVETVEYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEA 103
           T + T G       +KN++F ++DVGGQ   R  W H F++   +IF V  ++ ++V   
Sbjct: 133 TRVKTTGIVEVHFSFKNLNFKLFDVGGQRSERKKWIHCFEDVTAIIFCVAMSEYDQVLHE 312

Query: 104 REELMRMLAEDELRDAV----------LLVFANKQDL 130
            E   RM    +L D++          +++F NK+DL
Sbjct: 313 DETTNRMQESLKLFDSICNNKWFTDTSIILFLNKKDL 423
>34468
          Length = 1502

 Score = 47.0 bits (110), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 24/81 (29%), Positives = 45/81 (55%), Gaps = 6/81 (7%)
 Frame = +1

Query: 19  RILMVGLDAAGKTTILYKLKLGEIV-TTIPTIGFNVE----TVEYKNISFTVWDVGGQDK 73
           +I+++G    GKT + Y+  LG+    T  TIG +       V+ +++   +WD  GQ++
Sbjct: 499 KIIVIGDSNVGKTCLTYRFCLGKFPDKTEATIGVDFREKSIQVDSEHLKLQLWDTAGQER 678

Query: 74  IR-PLWRHYFQNTQGLIFVVD 93
            R  + +HY++N   ++FV D
Sbjct: 679 FRKSMVQHYYRNVHAVVFVYD 741
>29196
          Length = 431

 Score = 42.0 bits (97), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 21/63 (33%), Positives = 35/63 (55%)
 Frame = -2

Query: 59  KNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRD 118
           KN++F ++DVGGQ   R  W H F++   +IF V  ++ ++V    E   RM    +L D
Sbjct: 229 KNLNFKLFDVGGQRSERKKWIHCFEDVTAIIFCVAMSEYDQVLHEDETTNRMQESLKLFD 50

Query: 119 AVL 121
           ++ 
Sbjct: 49  SIC 41
>14775
          Length = 380

 Score = 41.6 bits (96), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 23/70 (32%), Positives = 36/70 (51%), Gaps = 6/70 (8%)
 Frame = -2

Query: 30  KTTILYKLKLGEIV-TTIPTIG-----FNVETVEYKNISFTVWDVGGQDKIRPLWRHYFQ 83
           KT +L + + G  +  T+PTI      FN    +  N+ +T+WD GG +  R LW  +F+
Sbjct: 379 KTCLLRRYQKGFFMDRTMPTIAVLCSEFNESRTDPLNVRYTLWDTGGAETYRSLWVSHFR 200

Query: 84  NTQGLIFVVD 93
             Q  + V D
Sbjct: 199 GAQVALLVYD 170
>13750
          Length = 503

 Score = 41.2 bits (95), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 23/70 (32%), Positives = 36/70 (51%), Gaps = 6/70 (8%)
 Frame = -2

Query: 30  KTTILYKLKLGEIV-TTIPTIG-----FNVETVEYKNISFTVWDVGGQDKIRPLWRHYFQ 83
           KT +L + + G  +  T+PTI      FN    +  N+ +T+WD GG +  R LW  +F+
Sbjct: 502 KTCLLRRYQKGFFMDRTMPTIAVLCSEFNESRTDPLNVRYTLWDTGGAETYRSLWVSHFR 323

Query: 84  NTQGLIFVVD 93
             Q  + V D
Sbjct: 322 GAQVALLVYD 293
>08428
          Length = 1109

 Score = 39.7 bits (91), Expect = 6e-04,   Method: Compositional matrix adjust.
 Identities = 29/120 (24%), Positives = 56/120 (46%), Gaps = 5/120 (4%)
 Frame = -3

Query: 16   KEMRILMVGLDAAGKTTILYKLKLGEI-VTTIPTIGFNVET----VEYKNISFTVWDVGG 70
            +++++ ++G    GK++I+ +   G    +   TIG +  +    V+     F +WD  G
Sbjct: 1074 RDVKVCLLGDSGVGKSSIVLRFVTGSYRPSQESTIGASFMSKSLVVDGAGYRFQIWDTAG 895

Query: 71   QDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAVLLVFANKQDL 130
            Q+K R L   Y++     + V D   R R  ++ +  ++ L      + VL +  NK DL
Sbjct: 894  QEKFRALAPMYYRGAAAAVIVYDVT-RPRTFKSVKSWIQELRSFGPPNIVLAIAGNKCDL 718
>19006
          Length = 568

 Score = 38.1 bits (87), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 37/146 (25%), Positives = 65/146 (44%), Gaps = 10/146 (6%)
 Frame = -2

Query: 14  GKKEMRILMVGLDAAGKTTILYKLKLGEIVTT-IPTIGFNVET---VEYKNISFTVWDVG 69
           G  + ++++VG  A GKT +L      +     +PT+  N      V+ K +   +WD  
Sbjct: 447 GCHKEKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDSKQVELALWDTA 268

Query: 70  GQ---DKIRPLWRHYFQNTQGLI--FVVDSNDR-ERVNEAREELMRMLAEDELRDAVLLV 123
           GQ   D++RPL    + +T  ++  F +DS D  E + E     +R        +  +++
Sbjct: 267 GQEDYDRLRPL---SYPDTDVILMCFSIDSPDSLENIPEKWTPEVRHFCP----NVPIIL 109

Query: 124 FANKQDLPNAMNAAEITDKLGLHSLR 149
             NK+DL N  N      K+    +R
Sbjct: 108 VGNKKDLRNDENTKRELMKMKQEPVR 31
>33374
          Length = 489

 Score = 37.0 bits (84), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 21/75 (28%), Positives = 36/75 (48%), Gaps = 3/75 (4%)
 Frame = +1

Query: 61  ISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAR---EELMRMLAEDELR 117
           + F +WD  GQ++   L   Y++  Q  I V D  +++    A+   +EL R  +     
Sbjct: 175 VKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNQDTFGRAKTWVKELQRQASP---- 342

Query: 118 DAVLLVFANKQDLPN 132
           + V+ +  NK DL N
Sbjct: 343 NIVIALAGNKADLAN 387
>35581
          Length = 364

 Score = 35.8 bits (81), Expect = 0.009,   Method: Compositional matrix adjust.
 Identities = 22/92 (23%), Positives = 47/92 (51%), Gaps = 7/92 (7%)
 Frame = +2

Query: 18  MRILMVGLDAAGKTTILYKLK----LGEIVTTIPTIGFNVETVEYKN---ISFTVWDVGG 70
            + +++G    GKT +L +L     L   +T++ T    + TV   +    S  +WD  G
Sbjct: 47  FKCVLLGDAGVGKTCLLNRLATDKFLDSPLTSLTTASL-LTTVTLTSGVMASVDLWDTAG 223

Query: 71  QDKIRPLWRHYFQNTQGLIFVVDSNDRERVNE 102
           Q++ R L   Y+++T+ ++ V D+  + ++ +
Sbjct: 224 QERYRSLTSSYYRDTKAVLIVYDAEHKLKLTD 319
>33380
          Length = 282

 Score = 35.8 bits (81), Expect = 0.009,   Method: Compositional matrix adjust.
 Identities = 18/74 (24%), Positives = 35/74 (47%)
 Frame = +3

Query: 59  KNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRD 118
           K +   +WD  GQ++ R +   Y++   G I + D  + E  N A ++    +      +
Sbjct: 54  KRVKLQIWDTAGQERYRTITTAYYRGAMGFILMYDVTNEESFN-AVQDWCTQIKTYSWDN 230

Query: 119 AVLLVFANKQDLPN 132
           A +++  NK DL +
Sbjct: 231 AQVVLVGNKCDLED 272
>20877
          Length = 381

 Score = 35.8 bits (81), Expect = 0.010,   Method: Compositional matrix adjust.
 Identities = 15/16 (93%), Positives = 16/16 (100%)
 Frame = -1

Query: 164 DGLYEGLDWLSNQLRN 179
           DGLYEGLDWLSNQL+N
Sbjct: 381 DGLYEGLDWLSNQLKN 334
>33794
          Length = 779

 Score = 34.7 bits (78), Expect = 0.022,   Method: Compositional matrix adjust.
 Identities = 15/52 (28%), Positives = 26/52 (50%), Gaps = 2/52 (3%)
 Frame = -1

Query: 48  TIGFNVETV--EYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDR 97
           T+ +   T+  E K +   +WD  GQ +   + R Y +  QG+I V D  ++
Sbjct: 695 TVAYKTTTILLEGKRVKLQIWDTSGQGRFCTIIRSYSRGAQGIILVYDITNK 540
>07465
          Length = 1103

 Score = 34.7 bits (78), Expect = 0.022,   Method: Compositional matrix adjust.
 Identities = 19/72 (26%), Positives = 38/72 (52%)
 Frame = +3

Query: 59  KNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRD 118
           +++   +WD  GQ++   + + Y++  Q  +    + DR+   EA E   R + EDE+ +
Sbjct: 339 EDVRLMLWDTAGQEEFDAITKAYYRGAQACVLAFSTVDRDSF-EALETWKRKV-EDEVGE 512

Query: 119 AVLLVFANKQDL 130
             +++  NK DL
Sbjct: 513 IGMVIVQNKIDL 548
>26083
          Length = 432

 Score = 34.7 bits (78), Expect = 0.024,   Method: Compositional matrix adjust.
 Identities = 26/125 (20%), Positives = 58/125 (46%), Gaps = 7/125 (5%)
 Frame = +1

Query: 10  KGLFGK--KEMRILMVGLDAAGKTTILYKLKLGEIVTTI-PTIGFNVET----VEYKNIS 62
            G FG   ++ +++ +G  + GKT+++ +        T   TIG +  +    +E + I 
Sbjct: 49  SGEFGNPLRKFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTIR 228

Query: 63  FTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAVLL 122
             +WD  GQ++ R L   Y +++   + V D  +    ++  + +  +  E    D +++
Sbjct: 229 LQLWDTAGQERFRSLIPSYIRDSSVAVVVYDITNANSFHQTSKWIDDVRTE-RGSDVIIM 405

Query: 123 VFANK 127
           +  NK
Sbjct: 406 LVGNK 420
>11728
          Length = 635

 Score = 33.1 bits (74), Expect = 0.061,   Method: Compositional matrix adjust.
 Identities = 23/73 (31%), Positives = 35/73 (47%), Gaps = 7/73 (9%)
 Frame = -1

Query: 12  LFGKKEMRILMVGLDAAGKTTILYKLKLGEIV-TTIPTIGFNVET---VEYKNISFTVWD 67
            F  + ++ ++VG  A GKT +L            IPT+  N      V+ K I+  +WD
Sbjct: 506 FFNMQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDSKPINLGLWD 327

Query: 68  VGGQ---DKIRPL 77
             GQ   D++RPL
Sbjct: 326 TAGQEDYDRLRPL 288
>13901
          Length = 962

 Score = 33.1 bits (74), Expect = 0.066,   Method: Compositional matrix adjust.
 Identities = 18/90 (20%), Positives = 41/90 (45%), Gaps = 14/90 (15%)
 Frame = -3

Query: 18  MRILMVGLDAAGKTTIL-----------YKLKLGEIVTTIPTIGFNVETVEYK---NISF 63
            +++++G    GKT+ +           YK+ +G        + F ++ + +    NI  
Sbjct: 285 FKVIIIGDPTVGKTSFVQRYVNDSFRRDYKMTIG--------VDFALKVIRWSDKCNIKL 130

Query: 64  TVWDVGGQDKIRPLWRHYFQNTQGLIFVVD 93
            +WD+ GQ++   + R Y+++    I + D
Sbjct: 129 QLWDIAGQERFTSMTRVYYKDAHACIVMFD 40
>26536
          Length = 829

 Score = 33.1 bits (74), Expect = 0.072,   Method: Compositional matrix adjust.
 Identities = 34/122 (27%), Positives = 53/122 (43%), Gaps = 10/122 (8%)
 Frame = +2

Query: 59  KNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLA--EDEL 116
           + +S+T  D  GQ++   +  HY ++  G I V    D     EA E + R L   +DE 
Sbjct: 122 RRVSWTFLDTAGQEEYSSMREHYTRSGDGFIVVYSVTDVTSFQEA-EAVFRWLTRFQDET 298

Query: 117 RDAVLLVFANKQDLPNAMNAA-----EITDKLGLHSLRHRNWYIQATCATSGDG---LYE 168
               +L   NK DL +          ++ D+LG+        Y + T A +GD    +Y 
Sbjct: 299 SIHAVLC-GNKTDLTSDRKVTPEEGRKMADRLGM-------LYFE-TSAKTGDNVSQVYH 451

Query: 169 GL 170
           GL
Sbjct: 452 GL 457
>17511
          Length = 483

 Score = 32.7 bits (73), Expect = 0.081,   Method: Compositional matrix adjust.
 Identities = 24/127 (18%), Positives = 55/127 (43%), Gaps = 14/127 (11%)
 Frame = -3

Query: 18  MRILMVGLDAAGKTTIL-----------YKLKLGEIVTTIPTIGFNVETVEYKNISFTVW 66
           ++++++G    GKT+++           YK  +G    T   +      V+ + ++  +W
Sbjct: 364 LKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVM------VDDRLVTMQIW 203

Query: 67  DVGGQDKIRPLWRHYFQNTQGLIFVVD---SNDRERVNEAREELMRMLAEDELRDAVLLV 123
           D  GQ++ + L   +++     + V D    N    ++  R+E +   +  +  +   +V
Sbjct: 202 DTAGQERFQSLGVAFYRGADCCVLVFDVTMPNTFRSLDSWRDEFLIQASPRDPENFPFVV 23

Query: 124 FANKQDL 130
             NK DL
Sbjct: 22  IGNKIDL 2
>05468
          Length = 1558

 Score = 30.8 bits (68), Expect = 0.36,   Method: Compositional matrix adjust.
 Identities = 23/92 (25%), Positives = 44/92 (47%), Gaps = 13/92 (14%)
 Frame = -3

Query: 15   KKE--MRILMVGLDAAGKTTIL-----------YKLKLGEIVTTIPTIGFNVETVEYKNI 61
            KKE   +IL++G    GKT+I+           Y+  +G +   +  + ++ +T+    I
Sbjct: 1553 KKEHLYKILVIGELGTGKTSIIKRYVHQFFSQHYRATIG-VDFALKVLNWDADTL----I 1389

Query: 62   SFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVD 93
               +WD+ GQ++   + R Y++   G   V D
Sbjct: 1388 RLQLWDIAGQERFGNMTRVYYKEAVGAFVVFD 1293
>01972
          Length = 2359

 Score = 27.3 bits (59), Expect = 3.7,   Method: Compositional matrix adjust.
 Identities = 15/56 (26%), Positives = 24/56 (42%), Gaps = 4/56 (7%)
 Frame = +3

Query: 46  IPTIGFNVETVEYKN----ISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDR 97
           + T+G  V  + +      + F VWD  GQ+K   L   Y+   Q  + + D   R
Sbjct: 390 VATLGVEVHPLLFHTSRGKLKFNVWDTAGQEKFGGLRDGYYIQGQCAVIMFDVTSR 557
>22540
          Length = 337

 Score = 26.9 bits (58), Expect = 4.1,   Method: Compositional matrix adjust.
 Identities = 11/12 (91%), Positives = 12/12 (100%)
 Frame = +2

Query: 166 LYEGLDWLSNQL 177
           LYEGLDWLSN+L
Sbjct: 2   LYEGLDWLSNEL 37
>34359
          Length = 1042

 Score = 26.9 bits (58), Expect = 4.7,   Method: Compositional matrix adjust.
 Identities = 28/130 (21%), Positives = 47/130 (36%), Gaps = 21/130 (16%)
 Frame = +3

Query: 46  IPTIGFNVETVEYKN----ISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDR---E 98
           + T+G  V  +++      + F VWD  GQ+K   L   Y+      I + D   R   +
Sbjct: 138 VATLGVEVHPLQFNTSRGLLRFNVWDTAGQEKFGGLRDGYYIQGTCAIIMFDVTSRVTYK 317

Query: 99  RVNEAREELMRML-------------AEDELRDAVLLVFANKQDLPNAMNAAEITDKLGL 145
            V     +L+R+               +D    A  +VF  K+      +    T  L  
Sbjct: 318 NVPNWHRDLVRVCENIPIVLCGNKVDIKDRKVKAKAIVFHRKRTCSTTTSVPRATTTLRS 497

Query: 146 HSLRHR-NWY 154
            S   R +W+
Sbjct: 498 RSCGWRASWW 527
>18743
          Length = 465

 Score = 26.2 bits (56), Expect = 7.3,   Method: Compositional matrix adjust.
 Identities = 22/50 (44%), Positives = 23/50 (46%), Gaps = 6/50 (12%)
 Frame = +2

Query: 20  ILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNV------ETVEYKNISF 63
           I MVGL A GKT I  KL        I T  FNV       T  YKN +F
Sbjct: 131 IAMVGLPARGKTYISKKLTRYLNWIGISTRAFNVGEYRRAATNSYKNHNF 280
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6680724|ref|NP_031507.1| ADP-ribosylation factor 6
[Mus musculus]
         (175 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

10862                                                                 246   2e-91
09827                                                                 264   1e-71
08153                                                                 257   2e-69
33605                                                                 104   3e-26
11378                                                                 100   6e-22
18208                                                                  97   3e-21
32860                                                                  87   2e-19
19506                                                                  69   7e-13
15973                                                                  64   4e-11
18949                                                                  62   9e-11
15662                                                                  60   6e-10
06991                                                                  56   8e-09
11965                                                                  51   3e-07
34468                                                                  46   7e-06
33374                                                                  45   2e-05
33380                                                                  43   7e-05
07465                                                                  42   1e-04
08428                                                                  41   2e-04
29196                                                                  39   8e-04
26083                                                                  39   0.001
14775                                                                  39   0.001
13750                                                                  39   0.001
33794                                                                  38   0.003
35581                                                                  37   0.003
17511                                                                  35   0.018
13901                                                                  34   0.025
19006                                                                  34   0.027
01972                                                                  34   0.036
27191                                                                  33   0.061
05468                                                                  32   0.13 
34359                                                                  32   0.13 
10402                                                                  30   0.61 
22781                                                                  29   1.2  
26536                                                                  28   1.7  
25960                                                                  28   2.3  
11257                                                                  28   2.8  
18743                                                                  27   4.0  
18169                                                                  26   7.1  
20544                                                                  26   7.9  
>10862
          Length = 2896

 Score =  246 bits (627), Expect(2) = 2e-91,   Method: Compositional matrix adjust.
 Identities = 113/121 (93%), Positives = 118/121 (97%)
 Frame = -3

Query: 55   KNVKFNVWDVGGQDKIRPLWRHYYTGTQGLIFVVDCADRDRIDEARQELHRIINDREMRD 114
            +  +FNVWDVGGQDKIRPLWRHYYTGTQGLIFVVDCADRDRIDEARQELHRIINDREMRD
Sbjct: 2492 QECQFNVWDVGGQDKIRPLWRHYYTGTQGLIFVVDCADRDRIDEARQELHRIINDREMRD 2313

Query: 115  AIILIFANKQDLPDAMKPHEIQEKLGLTRIRDRNWYVQPSCATSGDGLYEGLTWLTSNYK 174
            AIILIFANKQDLPDAMKPHEIQEKLGLTR+RDRNWYVQPSCAT+GDGL EGLTWLTSN+K
Sbjct: 2312 AIILIFANKQDLPDAMKPHEIQEKLGLTRLRDRNWYVQPSCATTGDGLCEGLTWLTSNHK 2133

Query: 175  S 175
            S
Sbjct: 2132 S 2130

 Score =  107 bits (266), Expect(2) = 2e-91,   Method: Compositional matrix adjust.
 Identities = 51/57 (89%), Positives = 56/57 (98%)
 Frame = -1

Query: 1    MGKVLSKIFGNKEMRILMLGLDAAGKTTILYKLKLGQSVTTIPTVGFNVETVTYKNV 57
            MGK+LSKIFGNKEMRILMLGLDAAGKTT+LYK+KLGQSVT IPTVGFNVETV++KNV
Sbjct: 2653 MGKLLSKIFGNKEMRILMLGLDAAGKTTLLYKMKLGQSVTXIPTVGFNVETVSFKNV 2483
>09827
          Length = 1201

 Score =  264 bits (675), Expect = 1e-71,   Method: Compositional matrix adjust.
 Identities = 120/171 (70%), Positives = 146/171 (85%)
 Frame = -3

Query: 5    LSKIFGNKEMRILMLGLDAAGKTTILYKLKLGQSVTTIPTVGFNVETVTYKNVKFNVWDV 64
            LS +FG K+MRILM+GLDAAGKTTILYKLKLG+ VTTIPT+GFNVETV YKN+ F VWDV
Sbjct: 1139 LSFMFGKKDMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNISFTVWDV 960

Query: 65   GGQDKIRPLWRHYYTGTQGLIFVVDCADRDRIDEARQELHRIINDREMRDAIILIFANKQ 124
            GGQDKIRPLWRHY+  TQGLIFVVD  D++R+ EAR+EL R++N+ E+RDA++L+FANKQ
Sbjct: 959  GGQDKIRPLWRHYFQNTQGLIFVVDSNDKERVQEAREELTRMLNEDELRDAVLLVFANKQ 780

Query: 125  DLPDAMKPHEIQEKLGLTRIRDRNWYVQPSCATSGDGLYEGLTWLTSNYKS 175
            DLP AM   EI EKLGL  +R+R WY+Q +CAT+GDGLYEGL WL++  K+
Sbjct: 779  DLPHAMATAEITEKLGLHGLRNRTWYIQSTCATTGDGLYEGLDWLSNQLKN 627
>08153
          Length = 1703

 Score =  257 bits (656), Expect = 2e-69,   Method: Compositional matrix adjust.
 Identities = 115/171 (67%), Positives = 142/171 (83%)
 Frame = +1

Query: 4   VLSKIFGNKEMRILMLGLDAAGKTTILYKLKLGQSVTTIPTVGFNVETVTYKNVKFNVWD 63
           +   +FG KE+RILM+GLDAAGKTTILYKLKLG+ VTTIPT+GFNVETV YKN+ F VWD
Sbjct: 55  LFKNLFGKKEVRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNISFTVWD 234

Query: 64  VGGQDKIRPLWRHYYTGTQGLIFVVDCADRDRIDEARQELHRIINDREMRDAIILIFANK 123
           VGGQDKIRPLWRHY+  TQGLIFVVD  DR+RI+EA++EL R++N+ ++RDAIIL+FANK
Sbjct: 235 VGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERINEAKEELARMLNEDDLRDAIILVFANK 414

Query: 124 QDLPDAMKPHEIQEKLGLTRIRDRNWYVQPSCATSGDGLYEGLTWLTSNYK 174
           QDLP+A    E+   LGL  ++ R WY+Q +CATSGDG+YEGL WL++  K
Sbjct: 415 QDLPNAYSASEVTAHLGLANLKGRKWYMQATCATSGDGMYEGLEWLSTTLK 567
>33605
          Length = 888

 Score =  104 bits (260), Expect(2) = 3e-26,   Method: Compositional matrix adjust.
 Identities = 50/92 (54%), Positives = 69/92 (75%), Gaps = 1/92 (1%)
 Frame = +1

Query: 12  KEMRILMLGLDAAGKTTILYKLKLGQSVTTI-PTVGFNVETVTYKNVKFNVWDVGGQDKI 70
           KE+R+LMLGLD AGKTTIL K   G+ + TI PT+GFN++T+ ++  K NVWDVGGQ  +
Sbjct: 493 KEVRLLMLGLDNAGKTTILKKFN-GEDIDTISPTLGFNIKTLEHRGFKLNVWDVGGQQSL 669

Query: 71  RPLWRHYYTGTQGLIFVVDCADRDRIDEARQE 102
           R  WR+Y+  T GL++VVD ADR RI + +++
Sbjct: 670 RSYWRNYFESTDGLVWVVDSADRMRIADCKRD 765

 Score = 30.0 bits (66), Expect(2) = 3e-26,   Method: Compositional matrix adjust.
 Identities = 12/39 (30%), Positives = 22/39 (56%)
 Frame = +3

Query: 103 LHRIINDREMRDAIILIFANKQDLPDAMKPHEIQEKLGL 141
           L  ++ +  +  A +L+FAN +  P A+   EIQ+ + L
Sbjct: 765 LQGLLVEERLAGATLLVFANSRTCPGALXSQEIQQAMDL 881
>11378
          Length = 1688

 Score = 99.8 bits (247), Expect = 6e-22,   Method: Compositional matrix adjust.
 Identities = 47/133 (35%), Positives = 79/133 (59%)
 Frame = +3

Query: 12  KEMRILMLGLDAAGKTTILYKLKLGQSVTTIPTVGFNVETVTYKNVKFNVWDVGGQDKIR 71
           K  +++ LGLD AGKTT+L+ LK  +    +PT+    E ++   ++F  +D+GG  + R
Sbjct: 318 KSGKLVFLGLDNAGKTTLLHMLKDDKMAQHVPTLHPTSEELSMGGMRFTTFDLGGHRQAR 497

Query: 72  PLWRHYYTGTQGLIFVVDCADRDRIDEARQELHRIINDREMRDAIILIFANKQDLPDAMK 131
            +W+ Y+    G++F+VD  DR+R+ EA+ EL  ++ D ++ +A IL+  NK D P A  
Sbjct: 498 RVWKDYFPAVDGIVFLVDVHDRERLVEAKAELDSLMTDEQVANAPILVLGNKIDKPGAAS 677

Query: 132 PHEIQEKLGLTRI 144
             EI+   GL  +
Sbjct: 678 EEEIRHWFGLNSL 716
>18208
          Length = 458

 Score = 97.1 bits (240), Expect = 3e-21,   Method: Compositional matrix adjust.
 Identities = 43/89 (48%), Positives = 62/89 (69%)
 Frame = -1

Query: 11  NKEMRILMLGLDAAGKTTILYKLKLGQSVTTIPTVGFNVETVTYKNVKFNVWDVGGQDKI 70
           ++E+RIL+LGLD AGKTT+L +L         PT GFN+++V  K  K NVWD+GGQ +I
Sbjct: 308 DRELRILLLGLDNAGKTTLLKQLASEDPSHITPTQGFNIKSVQSKGFKLNVWDIGGQRRI 129

Query: 71  RPLWRHYYTGTQGLIFVVDCADRDRIDEA 99
           RP W++Y+  T  LI+V+D +D  R++E 
Sbjct: 128 RPYWKNYFENTDLLIYVIDSSDTKRMEET 42
>32860
          Length = 330

 Score = 87.0 bits (214), Expect(2) = 2e-19,   Method: Compositional matrix adjust.
 Identities = 34/89 (38%), Positives = 57/89 (64%)
 Frame = +2

Query: 74  WRHYYTGTQGLIFVVDCADRDRIDEARQELHRIINDREMRDAIILIFANKQDLPDAMKPH 133
           W  YY+ ++ +I V+D  DR+R+   ++EL R++   E+R A +L+FANKQD+   M   
Sbjct: 8   WNTYYSNSEFIIMVIDSTDRERLSITKEELCRMLATEELRXAALLVFANKQDIKGCMSAA 187

Query: 134 EIQEKLGLTRIRDRNWYVQPSCATSGDGL 162
           EI  +L LT ++D  W++Q  C  +G+G+
Sbjct: 188 EISXQLNLTSVKDHVWHIQACCGLTGEGV 274

 Score = 24.6 bits (52), Expect(2) = 2e-19,   Method: Compositional matrix adjust.
 Identities = 8/14 (57%), Positives = 12/14 (85%)
 Frame = +1

Query: 161 GLYEGLTWLTSNYK 174
           GLY+GL W+TS+ +
Sbjct: 271 GLYQGLEWITSHIR 312
>19506
          Length = 421

 Score = 69.3 bits (168), Expect = 7e-13,   Method: Compositional matrix adjust.
 Identities = 32/52 (61%), Positives = 40/52 (76%)
 Frame = -3

Query: 1   MGKVLSKIFGNKEMRILMLGLDAAGKTTILYKLKLGQSVTTIPTVGFNVETV 52
           MG  L  +F  K + ++  GLDAAGKTT+LY LKLG+ VTTIPT+GFNVET+
Sbjct: 173 MGSALCTLFRQKPVTVIYFGLDAAGKTTLLYNLKLGEVVTTIPTIGFNVETL 18
>15973
          Length = 493

 Score = 63.5 bits (153), Expect = 4e-11,   Method: Compositional matrix adjust.
 Identities = 28/99 (28%), Positives = 56/99 (56%)
 Frame = -1

Query: 77  YYTGTQGLIFVVDCADRDRIDEARQELHRIINDREMRDAIILIFANKQDLPDAMKPHEIQ 136
           Y  G   ++++VD AD+D+++ +R ELH +++  +++   +L+  NK+DLP A+   E+ 
Sbjct: 487 YCRGVNAIVYMVDAADQDKLEASRNELHNLLDKPQLQGVPVLVLGNKRDLPGALDEKELI 308

Query: 137 EKLGLTRIRDRNWYVQPSCATSGDGLYEGLTWLTSNYKS 175
           +++ L+ I+DR            + +   L WL  + KS
Sbjct: 307 DRMNLSAIQDREICCYSISCKEKENIDITLQWLIQHSKS 191
>18949
          Length = 414

 Score = 62.4 bits (150), Expect = 9e-11,   Method: Compositional matrix adjust.
 Identities = 27/83 (32%), Positives = 47/83 (56%)
 Frame = +3

Query: 43  PTVGFNVETVTYKNVKFNVWDVGGQDKIRPLWRHYYTGTQGLIFVVDCADRDRIDEARQE 102
           PT     E ++   + F  +D+GG  + R +W+ Y+    G++F+VD  D +RI EA+ E
Sbjct: 15  PTGLPTSEELSMGGMTFTTFDLGGHRQARRVWKDYFPAVDGIVFIVDVHDTERITEAKAE 194

Query: 103 LHRIINDREMRDAIILIFANKQD 125
           L  ++ D ++ D  +L+  NK D
Sbjct: 195 LDSLLRDDQIADIPVLVLGNKMD 263
>15662
          Length = 455

 Score = 59.7 bits (143), Expect = 6e-10,   Method: Compositional matrix adjust.
 Identities = 27/73 (36%), Positives = 43/73 (58%)
 Frame = +2

Query: 69  KIRPLWRHYYTGTQGLIFVVDCADRDRIDEARQELHRIINDREMRDAIILIFANKQDLPD 128
           + R +W+ Y+    G++F+VD  DR+R  EA+ EL  ++ D ++ +A IL+  NK D P 
Sbjct: 2   QARRVWKDYFPAVDGIVFLVDVHDRERFVEAKAELDSLMTDEQVANAPILVLGNKIDKPG 181

Query: 129 AMKPHEIQEKLGL 141
           A    EI+   GL
Sbjct: 182 AASEDEIRHWFGL 220
>06991
          Length = 1860

 Score = 55.8 bits (133), Expect = 8e-09,   Method: Compositional matrix adjust.
 Identities = 22/66 (33%), Positives = 43/66 (65%)
 Frame = -2

Query: 107  INDREMRDAIILIFANKQDLPDAMKPHEIQEKLGLTRIRDRNWYVQPSCATSGDGLYEGL 166
            + + E++ +I+++FANKQD+  AM   E+   LGL  +++R + +  + A  G+GL E +
Sbjct: 1859 LEEDELKKSILMVFANKQDIEGAMTVTEVANSLGLPGLKNRKYQIFKTSAVKGEGLDEAM 1680

Query: 167  TWLTSN 172
             WL+++
Sbjct: 1679 EWLSNS 1662
>11965
          Length = 3256

 Score = 50.8 bits (120), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 29/97 (29%), Positives = 47/97 (48%), Gaps = 10/97 (10%)
 Frame = +1

Query: 40  TTIPTVGFNVETVTYKNVKFNVWDVGGQDKIRPLWRHYYTGTQGLIFVVDCADRD----- 94
           T + T G      ++KN+ F ++DVGGQ   R  W H +     +IF V  ++ D     
Sbjct: 133 TRVKTTGIVEVHFSFKNLNFKLFDVGGQRSERKKWIHCFEDVTAIIFCVAMSEYDQVLHE 312

Query: 95  -----RIDEARQELHRIINDREMRDAIILIFANKQDL 126
                R+ E+ +    I N++   D  I++F NK+DL
Sbjct: 313 DETTNRMQESLKLFDSICNNKWFTDTSIILFLNKKDL 423
>34468
          Length = 1502

 Score = 46.2 bits (108), Expect = 7e-06,   Method: Compositional matrix adjust.
 Identities = 27/93 (29%), Positives = 48/93 (51%), Gaps = 6/93 (6%)
 Frame = +1

Query: 3   KVLSKIFGNKEMRILMLGLDAAGKTTILYKLKLGQ-SVTTIPTVGFNVE----TVTYKNV 57
           KV+ K    +  +I+++G    GKT + Y+  LG+    T  T+G +       V  +++
Sbjct: 463 KVVEKQTQRRIFKIIVIGDSNVGKTCLTYRFCLGKFPDKTEATIGVDFREKSIQVDSEHL 642

Query: 58  KFNVWDVGGQDKIR-PLWRHYYTGTQGLIFVVD 89
           K  +WD  GQ++ R  + +HYY     ++FV D
Sbjct: 643 KLQLWDTAGQERFRKSMVQHYYRNVHAVVFVYD 741
>33374
          Length = 489

 Score = 45.1 bits (105), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 25/75 (33%), Positives = 37/75 (49%), Gaps = 3/75 (4%)
 Frame = +1

Query: 57  VKFNVWDVGGQDKIRPLWRHYYTGTQGLIFVVDCADRDRIDEAR---QELHRIINDREMR 113
           VKF +WD  GQ++   L   YY G Q  I V D  ++D    A+   +EL R    +   
Sbjct: 175 VKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNQDTFGRAKTWVKELQR----QASP 342

Query: 114 DAIILIFANKQDLPD 128
           + +I +  NK DL +
Sbjct: 343 NIVIALAGNKADLAN 387
>33380
          Length = 282

 Score = 43.1 bits (100), Expect = 7e-05,   Method: Compositional matrix adjust.
 Identities = 23/74 (31%), Positives = 36/74 (48%)
 Frame = +3

Query: 55  KNVKFNVWDVGGQDKIRPLWRHYYTGTQGLIFVVDCADRDRIDEARQELHRIINDREMRD 114
           K VK  +WD  GQ++ R +   YY G  G I + D  + +  + A Q+    I      +
Sbjct: 54  KRVKLQIWDTAGQERYRTITTAYYRGAMGFILMYDVTNEESFN-AVQDWCTQIKTYSWDN 230

Query: 115 AIILIFANKQDLPD 128
           A +++  NK DL D
Sbjct: 231 AQVVLVGNKCDLED 272
>07465
          Length = 1103

 Score = 42.4 bits (98), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 27/93 (29%), Positives = 46/93 (49%), Gaps = 2/93 (2%)
 Frame = +3

Query: 55  KNVKFNVWDVGGQDKIRPLWRHYYTGTQGLIFVVDCADRDRIDEARQELHRIINDREMRD 114
           ++V+  +WD  GQ++   + + YY G Q  +      DRD   EA +   R + D E+ +
Sbjct: 339 EDVRLMLWDTAGQEEFDAITKAYYRGAQACVLAFSTVDRDSF-EALETWKRKVED-EVGE 512

Query: 115 AIILIFANKQDLPD--AMKPHEIQEKLGLTRIR 145
             ++I  NK DL D   ++P E +      R+R
Sbjct: 513 IGMVIVQNKIDLIDDAVVRPEEAENLAKKLRLR 611
>08428
          Length = 1109

 Score = 41.2 bits (95), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 29/122 (23%), Positives = 56/122 (45%), Gaps = 5/122 (4%)
 Frame = -3

Query: 12   KEMRILMLGLDAAGKTTILYKLKLGQ-SVTTIPTVGFNVET----VTYKNVKFNVWDVGG 66
            +++++ +LG    GK++I+ +   G    +   T+G +  +    V     +F +WD  G
Sbjct: 1074 RDVKVCLLGDSGVGKSSIVLRFVTGSYRPSQESTIGASFMSKSLVVDGAGYRFQIWDTAG 895

Query: 67   QDKIRPLWRHYYTGTQGLIFVVDCADRDRIDEARQELHRIINDREMRDAIILIFANKQDL 126
            Q+K R L   YY G    + V D   R R  ++ +   + +      + ++ I  NK DL
Sbjct: 894  QEKFRALAPMYYRGAAAAVIVYDVT-RPRTFKSVKSWIQELRSFGPPNIVLAIAGNKCDL 718

Query: 127  PD 128
             +
Sbjct: 717  EE 712
>29196
          Length = 431

 Score = 39.3 bits (90), Expect = 8e-04,   Method: Compositional matrix adjust.
 Identities = 22/76 (28%), Positives = 36/76 (47%), Gaps = 10/76 (13%)
 Frame = -2

Query: 55  KNVKFNVWDVGGQDKIRPLWRHYYTGTQGLIFVVDCADRD----------RIDEARQELH 104
           KN+ F ++DVGGQ   R  W H +     +IF V  ++ D          R+ E+ +   
Sbjct: 229 KNLNFKLFDVGGQRSERKKWIHCFEDVTAIIFCVAMSEYDQVLHEDETTNRMQESLKLFD 50

Query: 105 RIINDREMRDAIILIF 120
            I N++   D  I++F
Sbjct: 49  SICNNKWFTDTSIILF 2
>26083
          Length = 432

 Score = 38.9 bits (89), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 27/122 (22%), Positives = 57/122 (46%), Gaps = 7/122 (5%)
 Frame = +1

Query: 9   FGN--KEMRILMLGLDAAGKTTILYKLKLGQSVTTI-PTVGFNVETVTY----KNVKFNV 61
           FGN  ++ +++ LG  + GKT+++ +        T   T+G +  + T     + ++  +
Sbjct: 58  FGNPLRKFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTIRLQL 237

Query: 62  WDVGGQDKIRPLWRHYYTGTQGLIFVVDCADRDRIDEARQELHRIINDREMRDAIILIFA 121
           WD  GQ++ R L   Y   +   + V D  + +   +  + +  +  +R   D II++  
Sbjct: 238 WDTAGQERFRSLIPSYIRDSSVAVVVYDITNANSFHQTSKWIDDVRTERG-SDVIIMLVG 414

Query: 122 NK 123
           NK
Sbjct: 415 NK 420
>14775
          Length = 380

 Score = 38.5 bits (88), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 22/70 (31%), Positives = 35/70 (50%), Gaps = 6/70 (8%)
 Frame = -2

Query: 26  KTTILYKLKLGQSV-TTIPTVG-----FNVETVTYKNVKFNVWDVGGQDKIRPLWRHYYT 79
           KT +L + + G  +  T+PT+      FN       NV++ +WD GG +  R LW  ++ 
Sbjct: 379 KTCLLRRYQKGFFMDRTMPTIAVLCSEFNESRTDPLNVRYTLWDTGGAETYRSLWVSHFR 200

Query: 80  GTQGLIFVVD 89
           G Q  + V D
Sbjct: 199 GAQVALLVYD 170
>13750
          Length = 503

 Score = 38.5 bits (88), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 18/54 (33%), Positives = 27/54 (50%), Gaps = 5/54 (9%)
 Frame = -2

Query: 41  TIPTVG-----FNVETVTYKNVKFNVWDVGGQDKIRPLWRHYYTGTQGLIFVVD 89
           T+PT+      FN       NV++ +WD GG +  R LW  ++ G Q  + V D
Sbjct: 454 TMPTIAVLCSEFNESRTDPLNVRYTLWDTGGAETYRSLWVSHFRGAQVALLVYD 293
>33794
          Length = 779

 Score = 37.7 bits (86), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 19/58 (32%), Positives = 28/58 (48%), Gaps = 2/58 (3%)
 Frame = -1

Query: 42  IPTVGFNVETVTY--KNVKFNVWDVGGQDKIRPLWRHYYTGTQGLIFVVDCADRDRID 97
           + TV +   T+    K VK  +WD  GQ +   + R Y  G QG+I V D  ++   D
Sbjct: 701 LQTVAYKTTTILLEGKRVKLQIWDTSGQGRFCTIIRSYSRGAQGIILVYDITNKWSFD 528
>35581
          Length = 364

 Score = 37.4 bits (85), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 24/83 (28%), Positives = 41/83 (49%), Gaps = 7/83 (8%)
 Frame = +2

Query: 14  MRILMLGLDAAGKTTILYKLK----LGQSVTTIPTVGFNVETVTYKN---VKFNVWDVGG 66
            + ++LG    GKT +L +L     L   +T++ T    + TVT  +      ++WD  G
Sbjct: 47  FKCVLLGDAGVGKTCLLNRLATDKFLDSPLTSLTTASL-LTTVTLTSGVMASVDLWDTAG 223

Query: 67  QDKIRPLWRHYYTGTQGLIFVVD 89
           Q++ R L   YY  T+ ++ V D
Sbjct: 224 QERYRSLTSSYYRDTKAVLIVYD 292
>17511
          Length = 483

 Score = 35.0 bits (79), Expect = 0.018,   Method: Compositional matrix adjust.
 Identities = 28/127 (22%), Positives = 52/127 (40%), Gaps = 14/127 (11%)
 Frame = -3

Query: 14  MRILMLGLDAAGKTTIL-----------YKLKLGQSVTTIPTVGFNVETVTYKNVKFNVW 62
           +++++LG    GKT+++           YK  +G    T   +      V  + V   +W
Sbjct: 364 LKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVM------VDDRLVTMQIW 203

Query: 63  DVGGQDKIRPLWRHYYTGTQGLIFVVDCADRD---RIDEARQELHRIINDREMRDAIILI 119
           D  GQ++ + L   +Y G    + V D    +    +D  R E     + R+  +   ++
Sbjct: 202 DTAGQERFQSLGVAFYRGADCCVLVFDVTMPNTFRSLDSWRDEFLIQASPRDPENFPFVV 23

Query: 120 FANKQDL 126
             NK DL
Sbjct: 22  IGNKIDL 2
>13901
          Length = 962

 Score = 34.3 bits (77), Expect = 0.025,   Method: Compositional matrix adjust.
 Identities = 21/100 (21%), Positives = 43/100 (43%), Gaps = 14/100 (14%)
 Frame = -3

Query: 14  MRILMLGLDAAGKTTIL-----------YKLKLGQSVTTIPTVGFNVETVTYK---NVKF 59
            +++++G    GKT+ +           YK+ +G        V F ++ + +    N+K 
Sbjct: 285 FKVIIIGDPTVGKTSFVQRYVNDSFRRDYKMTIG--------VDFALKVIRWSDKCNIKL 130

Query: 60  NVWDVGGQDKIRPLWRHYYTGTQGLIFVVDCADRDRIDEA 99
            +WD+ GQ++   + R YY      I + D   ++    A
Sbjct: 129 QLWDIAGQERFTSMTRVYYKDAHACIVMFDLTQKNTYQNA 10
>19006
          Length = 568

 Score = 34.3 bits (77), Expect = 0.027,   Method: Compositional matrix adjust.
 Identities = 28/95 (29%), Positives = 44/95 (46%), Gaps = 7/95 (7%)
 Frame = -2

Query: 5   LSKIFGNKEMRILMLGLDAAGKTTILYKLKLGQ-SVTTIPTVGFNVET---VTYKNVKFN 60
           +S   G  + +++++G  A GKT +L      Q     +PTV  N      V  K V+  
Sbjct: 462 ISSTNGCHKEKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDSKQVELA 283

Query: 61  VWDVGGQ---DKIRPLWRHYYTGTQGLIFVVDCAD 92
           +WD  GQ   D++RPL  +  T    + F +D  D
Sbjct: 282 LWDTAGQEDYDRLRPL-SYPDTDVILMCFSIDSPD 181
>01972
          Length = 2359

 Score = 33.9 bits (76), Expect = 0.036,   Method: Compositional matrix adjust.
 Identities = 25/94 (26%), Positives = 41/94 (43%), Gaps = 7/94 (7%)
 Frame = +3

Query: 42  IPTVGFNVETVTYKN----VKFNVWDVGGQDKIRPLWRHYYTGTQGLIFVVDCADR---D 94
           + T+G  V  + +      +KFNVWD  GQ+K   L   YY   Q  + + D   R    
Sbjct: 390 VATLGVEVHPLLFHTSRGKLKFNVWDTAGQEKFGGLRDGYYIQGQCAVIMFDVTSRVTYK 569

Query: 95  RIDEARQELHRIINDREMRDAIILIFANKQDLPD 128
            +    ++L R+       +  I++  NK D+ D
Sbjct: 570 NVPNWHRDLVRVC-----ENIPIVLCGNKVDIKD 656
>27191
          Length = 443

 Score = 33.1 bits (74), Expect = 0.061,   Method: Compositional matrix adjust.
 Identities = 18/78 (23%), Positives = 38/78 (48%), Gaps = 3/78 (3%)
 Frame = +1

Query: 32  KLKLGQSVTTIPTVGFNVETVTYKNVKFNVWDVGGQDKIRPLWRHYYTGTQGLIFVVDCA 91
           K   G   T     GF ++TV   +++ ++WD+ G ++   +    YTG+  +  V D +
Sbjct: 34  KFNQGYQPTVGVDYGFKIQTVNGVDMRVHMWDLSGSNEYLDVRNELYTGSDAIFIVFDVS 213

Query: 92  DR---DRIDEARQELHRI 106
           +    + +D   +E++R 
Sbjct: 214 NTPSFEALDSWLREINRF 267
>05468
          Length = 1558

 Score = 32.0 bits (71), Expect = 0.13,   Method: Compositional matrix adjust.
 Identities = 26/120 (21%), Positives = 52/120 (43%), Gaps = 9/120 (7%)
 Frame = -3

Query: 15   RILMLGLDAAGKTTILYKLK---LGQSVTTIPTVGFNVETVTYKN---VKFNVWDVGGQD 68
            +IL++G    GKT+I+ +       Q       V F ++ + +     ++  +WD+ GQ+
Sbjct: 1535 KILVIGELGTGKTSIIKRYVHQFFSQHYRATIGVDFALKVLNWDADTLIRLQLWDIAGQE 1356

Query: 69   KIRPLWRHYYTGTQGLIFVVD---CADRDRIDEARQELHRIINDREMRDAIILIFANKQD 125
            +   + R YY    G   V D    +  D + + + +L   +   +      ++ ANK D
Sbjct: 1355 RFGNMTRVYYKEAVGAFVVFDVTRASTFDAVTKWKNDLDSKVQLADGSPVPCVLLANKCD 1176
>34359
          Length = 1042

 Score = 32.0 bits (71), Expect = 0.13,   Method: Compositional matrix adjust.
 Identities = 24/94 (25%), Positives = 40/94 (42%), Gaps = 7/94 (7%)
 Frame = +3

Query: 42  IPTVGFNVETVTYKN----VKFNVWDVGGQDKIRPLWRHYYTGTQGLIFVVDCADR---D 94
           + T+G  V  + +      ++FNVWD  GQ+K   L   YY      I + D   R    
Sbjct: 138 VATLGVEVHPLQFNTSRGLLRFNVWDTAGQEKFGGLRDGYYIQGTCAIIMFDVTSRVTYK 317

Query: 95  RIDEARQELHRIINDREMRDAIILIFANKQDLPD 128
            +    ++L R+       +  I++  NK D+ D
Sbjct: 318 NVPNWHRDLVRVCE-----NIPIVLCGNKVDIKD 404
>10402
          Length = 2765

 Score = 29.6 bits (65), Expect = 0.61,   Method: Compositional matrix adjust.
 Identities = 15/45 (33%), Positives = 22/45 (48%), Gaps = 2/45 (4%)
 Frame = +3

Query: 52  VTYKNVKFNVWDVGGQDKIRPL--WRHYYTGTQGLIFVVDCADRD 94
           + Y ++  NVW VGG+ K+  L  W   +T   GL  V  C   +
Sbjct: 393 ILYCHLTCNVWSVGGRVKVSLLAHWEPLWTSAHGLHSVXMCVTLN 527
>22781
          Length = 1750

 Score = 28.9 bits (63), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 11/28 (39%), Positives = 15/28 (53%)
 Frame = -3

Query: 113  RDAIILIFANKQDLPDAMKPHEIQEKLG 140
            +D I+  F  K+  PD +KPH  Q   G
Sbjct: 1550 KDDIVFTFYKKRCCPDTLKPHPKQTVFG 1467
>26536
          Length = 829

 Score = 28.5 bits (62), Expect = 1.7,   Method: Compositional matrix adjust.
 Identities = 21/92 (22%), Positives = 35/92 (38%), Gaps = 5/92 (5%)
 Frame = +2

Query: 55  KNVKFNVWDVGGQDKIRPLWRHYYTGTQGLIFVVDCADRDRIDEARQELHRIINDREMRD 114
           + V +   D  GQ++   +  HY     G I V    D     EA      +   ++   
Sbjct: 122 RRVSWTFLDTAGQEEYSSMREHYTRSGDGFIVVYSVTDVTSFQEAEAVFRWLTRFQDETS 301

Query: 115 AIILIFANKQDLPDAMK--PHE---IQEKLGL 141
              ++  NK DL    K  P E   + ++LG+
Sbjct: 302 IHAVLCGNKTDLTSDRKVTPEEGRKMADRLGM 397
>25960
          Length = 420

 Score = 27.7 bits (60), Expect = 2.3,   Method: Compositional matrix adjust.
 Identities = 11/25 (44%), Positives = 17/25 (68%)
 Frame = -3

Query: 86  FVVDCADRDRIDEARQELHRIINDR 110
           F VD  ++D +DE    LHR+++DR
Sbjct: 337 FPVDSQEKDGVDELEDVLHRLVHDR 263
>11257
          Length = 1102

 Score = 27.7 bits (60), Expect = 2.8,   Method: Compositional matrix adjust.
 Identities = 18/98 (18%), Positives = 40/98 (40%), Gaps = 10/98 (10%)
 Frame = -2

Query: 39   VTTIPTVGFNVETVTYKNV-------KFNVWDVGGQDKIRPLWRHYYTGTQGLIFVVDCA 91
             + +P++  +   V +K+V          +WD  GQ++ + L   +Y GT   +      
Sbjct: 1101 TSLMPSLPHDRRGVPHKDVVVDGETFTMQIWDTAGQERYKSLRTPFYRGTDCCLLTFSVD 922

Query: 92   DRDRIDEARQELHRIINDREMRDAI---ILIFANKQDL 126
            +   +          +N  +++D+     +I  NK D+
Sbjct: 921  NLKSLQSLSDWYDEFVNYADIQDSASFPFVIIGNKADI 808
>18743
          Length = 465

 Score = 26.9 bits (58), Expect = 4.0,   Method: Compositional matrix adjust.
 Identities = 21/50 (42%), Positives = 24/50 (48%), Gaps = 6/50 (12%)
 Frame = +2

Query: 16  ILMLGLDAAGKTTILYKLKLGQSVTTIPTVGFNV------ETVTYKNVKF 59
           I M+GL A GKT I  KL    +   I T  FNV       T +YKN  F
Sbjct: 131 IAMVGLPARGKTYISKKLTRYLNWIGISTRAFNVGEYRRAATNSYKNHNF 280
>18169
          Length = 1219

 Score = 26.2 bits (56), Expect = 7.1,   Method: Compositional matrix adjust.
 Identities = 10/21 (47%), Positives = 14/21 (66%)
 Frame = +2

Query: 79  TGTQGLIFVVDCADRDRIDEA 99
           T T G++FV++C DR R   A
Sbjct: 920 TTTPGIVFVMECLDRTRTASA 982
>20544
          Length = 1132

 Score = 26.2 bits (56), Expect = 7.9,   Method: Compositional matrix adjust.
 Identities = 14/23 (60%), Positives = 15/23 (65%)
 Frame = +2

Query: 119 IFANKQDLPDAMKPHEIQEKLGL 141
           IF  K D+ D M PHEI EKL L
Sbjct: 323 IFKRKVDIHD-MSPHEIXEKLYL 388
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|170172560|ref|NP_035958.3| heparan sulfate
2-O-sulfotransferase 1 [Mus musculus]
         (356 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

11655                                                                 331   3e-91
14674                                                                 150   6e-37
18246                                                                 117   7e-27
34010                                                                  32   0.37 
>11655
          Length = 826

 Score =  331 bits (848), Expect = 3e-91,   Method: Compositional matrix adjust.
 Identities = 145/227 (63%), Positives = 180/227 (79%)
 Frame = -2

Query: 83  KTASTSFTNIAYDLCAKNRYHVLHINTTKNNPVMSLQDQVRFVKNITTWNEMKPGFYHGH 142
           +T STSF  I YDLC  N++HVLH+N TKN  ++SL DQ+RF+ NI++WNE KP FYHGH
Sbjct: 723 ETGSTSFAGIVYDLCQHNKFHVLHMNVTKNAKLLSLADQMRFITNISSWNEKKPAFYHGH 544

Query: 143 ISYLDFAKFGVKKKPIYINVIRDPIERLVSYYYFLRFGDDYRPGLRRRKQGDKKTFDECV 202
           ++++DF KFGV+K PIYIN+IRDPIER+VSYYYFLR+GDD+RP  +RRK GD +TFDECV
Sbjct: 543 LAFIDFNKFGVQKPPIYINMIRDPIERMVSYYYFLRYGDDFRPHAKRRKAGDHETFDECV 364

Query: 203 AEGGSDCAPEKLWLQIPFFCGHSSECWNVGSRWAMDQAKSNLINEYFLVGVTEELEDFIM 262
             G   C PE LW+QIPFFCGH  ECW  GS+WA++QAK N+++ Y LVGVTEEL DFI 
Sbjct: 363 ERGREHCDPENLWMQIPFFCGHIEECWVPGSQWALEQAKQNVLHNYLLVGVTEELADFIA 184

Query: 263 LLEAALPRFFRGATDLYRTGKKSHLRKTTEKKLPTKQTIAKLQQSDI 309
           +LEA LPRFF+GA  L+  G+KSHLRKT +K  P + TI KL QS+I
Sbjct: 183 VLEATLPRFFKGAMQLFNNGRKSHLRKTLKKYPPEQATIDKLHQSNI 43

 Score = 34.3 bits (77), Expect = 0.082,   Method: Compositional matrix adjust.
 Identities = 20/43 (46%), Positives = 25/43 (58%), Gaps = 5/43 (11%)
 Frame = -3

Query: 56  RH-TMDGPRQDATLDEEEDIIIIYNRVPKTAS----TSFTNIA 93
           RH T  G  QD     ++D+I+IYNRVPK A+     SFT  A
Sbjct: 806 RHLTSAGAEQDFLDSSQDDVIVIYNRVPKQAARHLPVSFTTYA 678

 Score = 30.8 bits (68), Expect = 0.82,   Method: Compositional matrix adjust.
 Identities = 14/37 (37%), Positives = 19/37 (51%)
 Frame = -3

Query: 286 HLRKTTEKKLPTKQTIAKLQQSDIWKMENEFYEFALE 322
           H R T + + P+            WKMENEFY+F L+
Sbjct: 101 H*RNTLQNRPPS----TNFTNPTFWKMENEFYDFVLD 3
>14674
          Length = 992

 Score =  150 bits (380), Expect = 6e-37,   Method: Compositional matrix adjust.
 Identities = 66/105 (62%), Positives = 79/105 (75%)
 Frame = +2

Query: 191 KQGDKKTFDECVAEGGSDCAPEKLWLQIPFFCGHSSECWNVGSRWAMDQAKSNLINEYFL 250
           K GD +TFDECV  G   C PE LW+QIPFFCGH  ECW  GS+WA++QAK N+++ Y L
Sbjct: 176 KAGDHETFDECVERGREHCDPENLWMQIPFFCGHIEECWVPGSQWALEQAKQNVLHNYLL 355

Query: 251 VGVTEELEDFIMLLEAALPRFFRGATDLYRTGKKSHLRKTTEKKL 295
           VGVTEEL DFI +LEA LPRFF+GA  L+  G+KSHLRKT +  L
Sbjct: 356 VGVTEELADFIAVLEATLPRFFKGAMQLFNNGRKSHLRKTLKNTL 490

 Score = 93.2 bits (230), Expect = 1e-19,   Method: Compositional matrix adjust.
 Identities = 70/208 (33%), Positives = 94/208 (45%), Gaps = 6/208 (2%)
 Frame = +1

Query: 152 GVKKKPIYINVIRDPIERLVSYYYFLRFGDDYRPGLRRRKQGDKKTF-DECVA-----EG 205
             +  PIYIN+IRDPIER+VSYYYFLR+GDD+RP   +RK    +     C A       
Sbjct: 58  ACRSPPIYINMIRDPIERMVSYYYFLRYGDDFRPQR*KRKSWRSRDV*RVCGAWS*ALRS 237

Query: 206 GSDCAPEKLWLQIPFFCGHSSECWNVGSRWAMDQAKSNLINEYFLVGVTEELEDFIMLLE 265
           G     +   L    + G      +VG R +  +  + L       G    +        
Sbjct: 238 GEPVDADSFLLWP--YRGVLGARQSVGIRTSQAECAAQLS----ACGRH*GIGRLHCCPG 399

Query: 266 AALPRFFRGATDLYRTGKKSHLRKTTEKKLPTKQTIAKLQQSDIWKMENEFYEFALEQFQ 325
           +       G     +   K    K TE+  P + TI KL QS+IWKMENEFY+F L+ F 
Sbjct: 400 SHFASLL*GGHATLQ*WPKVPPEKDTEEYPPEQATIDKLHQSNIWKMENEFYDFVLDHFH 579

Query: 326 FIRAHAVREKDGDLYILAQNFFYEKIYP 353
           +I+       DG+       F YEKI P
Sbjct: 580 YIKQRTFDVIDGEYLEKGHRFQYEKIRP 663
>18246
          Length = 465

 Score =  117 bits (293), Expect = 7e-27,   Method: Compositional matrix adjust.
 Identities = 58/125 (46%), Positives = 85/125 (68%), Gaps = 2/125 (1%)
 Frame = -3

Query: 231 VGSR--WAMDQAKSNLINEYFLVGVTEELEDFIMLLEAALPRFFRGATDLYRTGKKSHLR 288
           +G+R    + QAK NL+NEYFLVGVTE++ +F+ LLE +LPR F+G  + Y+   KSHLR
Sbjct: 463 LGTRQ*LGLKQAKRNLVNEYFLVGVTEQMFEFVDLLERSLPRIFQGFREHYQNSNKSHLR 284

Query: 289 KTTEKKLPTKQTIAKLQQSDIWKMENEFYEFALEQFQFIRAHAVREKDGDLYILAQNFFY 348
            T+ K  P++ T+  +Q+S IW+MEN+ Y+FALEQF+F +   ++  +  L    Q F Y
Sbjct: 283 VTSSKIAPSESTVQTIQRSKIWQMENDLYKFALEQFEFTKKKLMQPDNKHL----QQFMY 116

Query: 349 EKIYP 353
           EK+ P
Sbjct: 115 EKVRP 101
>34010
          Length = 832

 Score = 32.0 bits (71), Expect = 0.37,   Method: Compositional matrix adjust.
 Identities = 18/65 (27%), Positives = 34/65 (52%)
 Frame = +3

Query: 284 KSHLRKTTEKKLPTKQTIAKLQQSDIWKMENEFYEFALEQFQFIRAHAVREKDGDLYILA 343
           + H R+   ++   + T+ +L  +D+WK   E  +  LE +QF R  AV E     +++A
Sbjct: 207 RKHYRQEEVREKLIQLTLERLDMTDLWKDRWEHLQLILEVYQFARDAAVAEA----WLVA 374

Query: 344 QNFFY 348
           Q  ++
Sbjct: 375 QEQYF 389
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|45592934|ref|NP_033033.1| RAS-related C3 botulinum
substrate 1 [Mus musculus]
         (192 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

11728                                                                 328   8e-91
19656                                                                 222   7e-59
19006                                                                 185   1e-47
31291                                                                 169   5e-43
17872                                                                 137   4e-33
10708                                                                  95   1e-20
08428                                                                  78   2e-15
17511                                                                  70   4e-13
00858                                                                  69   1e-12
01972                                                                  57   2e-12
34468                                                                  67   4e-12
26083                                                                  65   2e-11
07580                                                                  64   3e-11
14456                                                                  63   6e-11
09700                                                                  62   2e-10
07465                                                                  58   3e-09
13750                                                                  57   6e-09
32770                                                                  56   9e-09
34359                                                                  56   1e-08
33374                                                                  55   1e-08
30760                                                                  55   2e-08
11257                                                                  53   6e-08
35581                                                                  52   2e-07
13901                                                                  52   2e-07
36757                                                                  50   5e-07
27191                                                                  50   5e-07
33794                                                                  50   7e-07
26536                                                                  49   9e-07
33380                                                                  49   1e-06
36482                                                                  46   7e-06
05468                                                                  44   3e-05
01398                                                                  43   9e-05
00552                                                                  40   4e-04
09204                                                                  40   4e-04
06994                                                                  30   0.43 
14775                                                                  30   0.47 
14139                                                                  27   6.3  
23830                                                                  27   6.7  
>11728
          Length = 635

 Score =  328 bits (841), Expect = 8e-91,   Method: Compositional matrix adjust.
 Identities = 154/165 (93%), Positives = 161/165 (97%)
 Frame = -1

Query: 1   MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAG 60
           MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVD KP+NLGLWDTAG
Sbjct: 497 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDSKPINLGLWDTAG 318

Query: 61  QEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLR 120
           QEDYDRLRPLSYPQTDVFLICFSL+SPASFENV+AKWYPEV HHCPNTPIILVGTKLDLR
Sbjct: 317 QEDYDRLRPLSYPQTDVFLICFSLISPASFENVKAKWYPEVSHHCPNTPIILVGTKLDLR 138

Query: 121 DDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGL 165
           +DK+TIEKLKEKKL PITYPQGLAMAK+IGA KYLECSALTQ+GL
Sbjct: 137 EDKETIEKLKEKKLAPITYPQGLAMAKDIGAGKYLECSALTQKGL 3
>19656
          Length = 428

 Score =  222 bits (566), Expect = 7e-59,   Method: Compositional matrix adjust.
 Identities = 101/108 (93%), Positives = 105/108 (97%)
 Frame = +3

Query: 1   MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAG 60
           MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDG+PVNLGLWDTAG
Sbjct: 105 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGRPVNLGLWDTAG 284

Query: 61  QEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNT 108
           QEDYDRLRPLSYPQTDVFL+CFS+ SPASFEN+RAKWYPEV HHCP T
Sbjct: 285 QEDYDRLRPLSYPQTDVFLLCFSVASPASFENIRAKWYPEVNHHCPGT 428
>19006
          Length = 568

 Score =  185 bits (469), Expect = 1e-47,   Method: Compositional matrix adjust.
 Identities = 86/144 (59%), Positives = 105/144 (72%)
 Frame = -2

Query: 5   KCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDY 64
           K V+VGDGA GKTCLLI ++ + FP  Y+PTVF+NY A++ VD K V L LWDTAGQEDY
Sbjct: 432 KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDSKQVELALWDTAGQEDY 253

Query: 65  DRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKD 124
           DRLRPLSYP TDV L+CFS+ SP S EN+  KW PEVRH CPN PIILVG K DLR+D++
Sbjct: 252 DRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVRHFCPNVPIILVGNKKDLRNDEN 73

Query: 125 TIEKLKEKKLTPITYPQGLAMAKE 148
           T  +L + K  P+   +     +E
Sbjct: 72  TKRELMKMKQEPVRLDRRARHVRE 1
>31291
          Length = 446

 Score =  169 bits (429), Expect = 5e-43,   Method: Compositional matrix adjust.
 Identities = 74/122 (60%), Positives = 94/122 (77%)
 Frame = -1

Query: 53  LGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIIL 112
           L LWDTAGQEDYDRLRPL+YP TDVF++ FSL+S AS +NV+ KWYPE+RHH P+ PI+L
Sbjct: 446 LQLWDTAGQEDYDRLRPLAYPNTDVFMLXFSLMSEASMKNVKVKWYPEIRHHDPHVPIVL 267

Query: 113 VGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEA 172
           VGTKLDLR DK+ + KL+  +  P++  QG  +AK I A +Y ECS+ TQ  LKT F+E 
Sbjct: 266 VGTKLDLRQDKEAVRKLRSSRQDPVSSNQGNDLAKAIKAKRYFECSSKTQENLKTAFEET 87

Query: 173 IR 174
           +R
Sbjct: 86  VR 81
>17872
          Length = 700

 Score =  137 bits (344), Expect = 4e-33,   Method: Compositional matrix adjust.
 Identities = 61/115 (53%), Positives = 86/115 (74%)
 Frame = -1

Query: 61  QEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLR 120
           Q+D+D LRPL YP+T+VFL+CFS+VSP SF NV  KW PE+R+HCP  P+++VGT+ DLR
Sbjct: 700 QDDFDSLRPLCYPETNVFLLCFSVVSPTSFHNVMEKWVPELRYHCPGAPLVVVGTQSDLR 521

Query: 121 DDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRA 175
           +D   + +L + K  P++  + + MA ++GA +Y+ECSALTQ+ LK VFD  I A
Sbjct: 520 NDVKVLIELAKYKEKPVSEEEAVKMADQLGA-QYVECSALTQKNLKEVFDTGILA 359
>10708
          Length = 2775

 Score = 95.1 bits (235), Expect = 1e-20,   Method: Compositional matrix adjust.
 Identities = 47/102 (46%), Positives = 66/102 (64%), Gaps = 1/102 (0%)
 Frame = -3

Query: 75   TDVFLICFS-LVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTIEKLKEKK 133
            T +  +C S L +  ++     KW PEVRH CPN PIILVG K DLR+D++T  +L + K
Sbjct: 2653 TQMSSLCASPLTALTAWRTSLKKWTPEVRHFCPNVPIILVGNKKDLRNDENTKRELMKMK 2474

Query: 134  LTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRA 175
              P+   +G AM+++I A  YLECSA T+ G++ VF+ A RA
Sbjct: 2473 QEPVRLDEGRAMSEKINAYSYLECSAKTKEGVREVFETATRA 2348

 Score = 76.3 bits (186), Expect = 8e-15,   Method: Compositional matrix adjust.
 Identities = 34/46 (73%), Positives = 37/46 (80%)
 Frame = -2

Query: 51   VNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAK 96
            V L LWDTAGQEDYDRLRPLSYP TDV L+CFS+ SP S EN+  K
Sbjct: 2723 VELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEK 2586
>08428
          Length = 1109

 Score = 77.8 bits (190), Expect = 2e-15,   Method: Compositional matrix adjust.
 Identities = 48/176 (27%), Positives = 91/176 (51%), Gaps = 2/176 (1%)
 Frame = -3

Query: 1    MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNY-SANVMVDGKPVNLGLWDTA 59
            M+ +K  ++GD  VGK+ +++ + T ++      T+  ++ S +++VDG      +WDTA
Sbjct: 1077 MRDVKVCLLGDSGVGKSSIVLRFVTGSYRPSQESTIGASFMSKSLVVDGAGYRFQIWDTA 898

Query: 60   GQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHC-PNTPIILVGTKLD 118
            GQE +  L P+ Y      +I + +  P +F++V++ W  E+R    PN  + + G K D
Sbjct: 897  GQEKFRALAPMYYRGAAAAVIVYDVTRPRTFKSVKS-WIQELRSFGPPNIVLAIAGNKCD 721

Query: 119  LRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIR 174
            L + ++ +EK  ++             A  I A+ + E SA+T   ++ +F E  R
Sbjct: 720  LEELREVVEKDAQE------------YASSISAI-FGETSAMTAVNVEEMFTELAR 592
>17511
          Length = 483

 Score = 70.5 bits (171), Expect = 4e-13,   Method: Compositional matrix adjust.
 Identities = 39/122 (31%), Positives = 62/122 (50%), Gaps = 6/122 (4%)
 Frame = -3

Query: 4   IKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTV-FDNYSANVMVDGKPVNLGLWDTAGQE 62
           +K +++GD  VGKT L+  Y    F  +Y  T+  D  +  VMVD + V + +WDTAGQE
Sbjct: 364 LKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQIWDTAGQE 185

Query: 63  DYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCP-----NTPIILVGTKL 117
            +  L    Y   D  ++ F +  P +F ++ + W  E           N P +++G K+
Sbjct: 184 RFQSLGVAFYRGADCCVLVFDVTMPNTFRSLDS-WRDEFLIQASPRDPENFPFVVIGNKI 8

Query: 118 DL 119
           DL
Sbjct: 7   DL 2
>00858
          Length = 1658

 Score = 68.9 bits (167), Expect = 1e-12,   Method: Compositional matrix adjust.
 Identities = 47/161 (29%), Positives = 78/161 (48%), Gaps = 2/161 (1%)
 Frame = -2

Query: 16   KTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQT 75
            K+ L I    N F  EY PT  D+    V++DG+   L + DTAGQE+   +R       
Sbjct: 1552 KSALTIQLXQNHFVEEYDPTXEDSXRKQVVIDGETCLLDILDTAGQEEXSAMRDQCMRTG 1373

Query: 76   DVFLICFSLVSPASFENVRAKWYPEVRH--HCPNTPIILVGTKLDLRDDKDTIEKLKEKK 133
            + FL  F++ +  SFE++  ++  +++        P++LVG K+DL              
Sbjct: 1372 EGFLCVFAVXNLKSFEDIN-QYREQIKRVKDADEVPMVLVGNKVDL-------------P 1235

Query: 134  LTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIR 174
            +  +   QG  MA E+  + Y+E SA T++G+   F   +R
Sbjct: 1234 IRNVEQRQGKHMA-ELYHIPYVETSAKTRQGVDDAFYTLVR 1115
>01972
          Length = 2359

 Score = 56.6 bits (135), Expect(2) = 2e-12,   Method: Compositional matrix adjust.
 Identities = 27/73 (36%), Positives = 42/73 (57%)
 Frame = +3

Query: 51  VNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPI 110
           +   +WDTAGQE +  LR   Y Q    +I F + S  +++NV   W+ ++   C N PI
Sbjct: 447 LKFNVWDTAGQEKFGGLRDGYYIQGQCAVIMFDVTSRVTYKNV-PNWHRDLVRVCENIPI 623

Query: 111 ILVGTKLDLRDDK 123
           +L G K+D++D K
Sbjct: 624 VLCGNKVDIKDRK 662

 Score = 31.2 bits (69), Expect(2) = 2e-12,   Method: Compositional matrix adjust.
 Identities = 13/32 (40%), Positives = 17/32 (53%)
 Frame = +1

Query: 3   AIKCVVVGDGAVGKTCLLISYTTNAFPGEYIP 34
             K V+VGDG VGKT  +  + T  F    +P
Sbjct: 301 TFKLVLVGDGGVGKTTFVKRHVTGEFEKNMLP 396
>34468
          Length = 1502

 Score = 67.4 bits (163), Expect = 4e-12,   Method: Compositional matrix adjust.
 Identities = 41/119 (34%), Positives = 59/119 (49%), Gaps = 4/119 (3%)
 Frame = +1

Query: 5   KCVVVGDGAVGKTCLLISYTTNAFPGEYIPTV-FDNYSANVMVDGKPVNLGLWDTAGQED 63
           K +V+GD  VGKTCL   +    FP +   T+  D    ++ VD + + L LWDTAGQE 
Sbjct: 499 KIIVIGDSNVGKTCLTYRFCLGKFPDKTEATIGVDFREKSIQVDSEHLKLQLWDTAGQER 678

Query: 64  YDR-LRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHH--CPNTPIILVGTKLDL 119
           + + +    Y      +  + +   +SFEN+ A W  E   H      P ILVG K D+
Sbjct: 679 FRKSMVQHYYRNVHAVVFVYDMTKMSSFENMPA-WIEECDRHNLTKYIPRILVGNKCDV 852
>26083
          Length = 432

 Score = 65.1 bits (157), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 36/118 (30%), Positives = 62/118 (52%), Gaps = 2/118 (1%)
 Frame = +1

Query: 1   MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTV-FDNYSANVMVDGKPVNLGLWDTA 59
           ++  K V +G+ +VGKT L+  +  ++F   Y  T+  D  S  + ++ + + L LWDTA
Sbjct: 70  LRKFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTIRLQLWDTA 249

Query: 60  GQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVR-HHCPNTPIILVGTK 116
           GQE +  L P     + V ++ + + +  SF    +KW  +VR     +  I+LVG K
Sbjct: 250 GQERFRSLIPSYIRDSSVAVVVYDITNANSFHQT-SKWIDDVRTERGSDVIIMLVGNK 420
>07580
          Length = 921

 Score = 64.3 bits (155), Expect = 3e-11,   Method: Compositional matrix adjust.
 Identities = 43/162 (26%), Positives = 76/162 (46%), Gaps = 1/162 (0%)
 Frame = +3

Query: 14  VGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYP 73
           + K   L S     F  +Y PT+ D+Y   V VDG+   L + DTAG E +  +R L   
Sbjct: 93  LAKVL*LYSLCKGIFVEKYDPTIEDSYRKQVEVDGQQCMLEILDTAGTEQFTAMRDLYMK 272

Query: 74  QTDVFLICFSLVSPASFENVRAKWYPEVR-HHCPNTPIILVGTKLDLRDDKDTIEKLKEK 132
               FL+ +S+ + ++F +++      +R     + P++LVG K DL D++         
Sbjct: 273 NGQGFLLAYSITAQSTFNDLQELREQILRVKDTDDVPMLLVGNKCDLEDER--------- 425

Query: 133 KLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIR 174
               +   QG  +A+   +  +LE SA  +  +  +F + +R
Sbjct: 426 ---VVGKDQGQGLARSF-SCAFLETSAKARINVNEIFMDLVR 539
>14456
          Length = 1867

 Score = 63.2 bits (152), Expect = 6e-11,   Method: Compositional matrix adjust.
 Identities = 37/125 (29%), Positives = 65/125 (52%), Gaps = 6/125 (4%)
 Frame = -1

Query: 12   GAVGKTCLLISYTTNAFPGEYIPTV-FDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPL 70
            G VGK+ L+  + +N F  +   T+  +  + +V+VD +   + +WDTAGQE +  LR  
Sbjct: 1114 GGVGKSSLMNRFVSNKFDAQSFHTIGVEFLNKDVVVDDETYTMQIWDTAGQERFKSLRTP 935

Query: 71   SYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCP-----NTPIILVGTKLDLRDDKDT 125
             Y   D  L+ FS+ S  SF N+ + W  E  ++         P +++G K+D+   + T
Sbjct: 934  FYRGADCCLLTFSVDSMQSFRNL-SMWRKEFLYYADIQDGVTFPFVVLGNKIDVEGRQVT 758

Query: 126  IEKLK 130
             E+ +
Sbjct: 757  NEEAR 743
>09700
          Length = 1855

 Score = 62.0 bits (149), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 30/71 (42%), Positives = 47/71 (66%)
 Frame = -1

Query: 103  HHCPNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQ 162
            ++ P TP++LVGT+ DLR+D   + +L + K  P++      +A ++GA  Y+ECSALTQ
Sbjct: 1831 NNSPRTPLVLVGTQSDLRNDVKVLIELAKYKEKPVSEDDASKLAHQLGA-SYVECSALTQ 1655

Query: 163  RGLKTVFDEAI 173
            + LK +FD  I
Sbjct: 1654 KNLKEMFDSCI 1622
>07465
          Length = 1103

 Score = 57.8 bits (138), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 33/107 (30%), Positives = 51/107 (47%), Gaps = 1/107 (0%)
 Frame = +3

Query: 17  TCLLISYTTNAFPGEYIPTV-FDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQT 75
           + ++  Y    F  +Y  T+  D     + V G+ V L LWDTAGQE++D +    Y   
Sbjct: 240 SSMIQRYCKGIFTKDYKKTIGVDFLERQIEVGGEDVRLMLWDTAGQEEFDAITKAYYRGA 419

Query: 76  DVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDD 122
              ++ FS V   SFE +   W  +V        +++V  K+DL DD
Sbjct: 420 QACVLAFSTVDRDSFEALET-WKRKVEDEVGEIGMVIVQNKIDLIDD 557
>13750
          Length = 503

 Score = 56.6 bits (135), Expect = 6e-09,   Method: Compositional matrix adjust.
 Identities = 43/158 (27%), Positives = 66/158 (41%), Gaps = 2/158 (1%)
 Frame = -2

Query: 16  KTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNL--GLWDTAGQEDYDRLRPLSYP 73
           KTCLL  Y    F    +PT+    S        P+N+   LWDT G E Y  L    + 
Sbjct: 502 KTCLLRRYQKGFFMDRTMPTIAVLCSEFNESRTDPLNVRYTLWDTGGAETYRSLWVSHFR 323

Query: 74  QTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTIEKLKEKK 133
              V L+ + +    SF      W   +  + P   +I VG+K DL +++          
Sbjct: 322 GAQVALLVYDVTCEWSFLTATTVWRKALMKNIPEAQVIFVGSKTDLEENR---------- 173

Query: 134 LTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDE 171
              I+  +G A A + G   + E S++T + +  VF E
Sbjct: 172 --VISTERGQAFATQCG-YTFFETSSVTGKNVDAVFWE 68
>32770
          Length = 387

 Score = 55.8 bits (133), Expect = 9e-09,   Method: Compositional matrix adjust.
 Identities = 33/80 (41%), Positives = 43/80 (53%), Gaps = 5/80 (6%)
 Frame = +2

Query: 99  PEVRHHCPNTPIILVGTKLDLRD-----DKDTIEKLKEKKLTPITYPQGLAMAKEIGAVK 153
           PE+R + P TP ILVGT+ DLR       KD +   K KKL           A+++GA+ 
Sbjct: 2   PELRDYRPGTPFILVGTQADLRHHSQPASKDMVPAHKGKKL-----------ARKVGALG 148

Query: 154 YLECSALTQRGLKTVFDEAI 173
           Y ECSAL   GL  VF + +
Sbjct: 149 YFECSALIGSGLDRVFRQVV 208
>34359
          Length = 1042

 Score = 55.8 bits (133), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 27/73 (36%), Positives = 42/73 (57%)
 Frame = +3

Query: 51  VNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPI 110
           +   +WDTAGQE +  LR   Y Q    +I F + S  +++NV   W+ ++   C N PI
Sbjct: 195 LRFNVWDTAGQEKFGGLRDGYYIQGTCAIIMFDVTSRVTYKNV-PNWHRDLVRVCENIPI 371

Query: 111 ILVGTKLDLRDDK 123
           +L G K+D++D K
Sbjct: 372 VLCGNKVDIKDRK 410
>33374
          Length = 489

 Score = 55.5 bits (132), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 41/142 (28%), Positives = 65/142 (45%), Gaps = 2/142 (1%)
 Frame = +1

Query: 29  PGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPA 88
           PGEY  + F   +  V +D   V   +WDTAGQE Y  L P+ Y      ++ + + +  
Sbjct: 115 PGEYDWSCF--LTQTVCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNQD 288

Query: 89  SFENVRAK-WYPEV-RHHCPNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMA 146
           +F   RAK W  E+ R   PN  I L G K DL + +             + + +  A A
Sbjct: 289 TFG--RAKTWVKELQRQASPNIVIALAGNKADLANKR------------MVEFEEAQAYA 426

Query: 147 KEIGAVKYLECSALTQRGLKTV 168
           +E  ++ ++E SA T   +  +
Sbjct: 427 EE-NSLLFMETSAKTAMNVNDI 489
>30760
          Length = 596

 Score = 54.7 bits (130), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 49/176 (27%), Positives = 76/176 (43%), Gaps = 11/176 (6%)
 Frame = -1

Query: 5   KCVVVGDGAVGKT--CLLISYTTNAFPGEYIPTVFDNYSANVMV------DGK-PVNLGL 55
           KC+V GD  VGK+  C +    +  FP  Y  T        V+V      D +  V L L
Sbjct: 524 KCIVTGDSGVGKSSICQVFHSDSAHFPKNYSMTT----GVEVLVKLVNIPDSRDQVELYL 357

Query: 56  WDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNT--PIILV 113
           +D+AG+E +       + Q  V ++ + +    SF     +W   VR   PNT  P +LV
Sbjct: 356 FDSAGKEIFSENVTKFWDQPSVVMVVYDVTDETSFSGC-VRWLERVRAAKPNTVIPGVLV 180

Query: 114 GTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVF 169
             K DL + +             ++  +G  +A+  G ++Y ECSA   +   T F
Sbjct: 179 ANKTDLDERR------------RVSRKEGKDLAQSHG-LEYFECSAKEMQNTDTPF 51
>11257
          Length = 1102

 Score = 53.1 bits (126), Expect = 6e-08,   Method: Compositional matrix adjust.
 Identities = 35/137 (25%), Positives = 63/137 (45%), Gaps = 5/137 (3%)
 Frame = -2

Query: 43   NVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVR 102
            +V+VDG+   + +WDTAGQE Y  LR   Y  TD  L+ FS+ +  S +++ + WY E  
Sbjct: 1050 DVVVDGETFTMQIWDTAGQERYKSLRTPFYRGTDCCLLTFSVDNLKSLQSL-SDWYDEFV 874

Query: 103  HHC-----PNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLEC 157
            ++       + P +++G K D+ + +             ++        +  G + Y E 
Sbjct: 873  NYADIQDSASFPFVIIGNKADIEERE-------------VSSEDAYNWCRTHGNLPYFET 733

Query: 158  SALTQRGLKTVFDEAIR 174
            SA     ++  F   +R
Sbjct: 732  SAKDSLNVQQAFLAVVR 682
>35581
          Length = 364

 Score = 51.6 bits (122), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 30/81 (37%), Positives = 39/81 (48%), Gaps = 2/81 (2%)
 Frame = +2

Query: 4   IKCVVVGDGAVGKTCLLISYTTNAFPGEYIP--TVFDNYSANVMVDGKPVNLGLWDTAGQ 61
            KCV++GD  VGKTCLL    T+ F    +   T     +   +  G   ++ LWDTAGQ
Sbjct: 47  FKCVLLGDAGVGKTCLLNRLATDKFLDSPLTSLTTASLLTTVTLTSGVMASVDLWDTAGQ 226

Query: 62  EDYDRLRPLSYPQTDVFLICF 82
           E Y  L    Y  T   LI +
Sbjct: 227 ERYRSLTSSYYRDTKAVLIVY 289
>13901
          Length = 962

 Score = 51.6 bits (122), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 25/91 (27%), Positives = 46/91 (50%), Gaps = 2/91 (2%)
 Frame = -3

Query: 4   IKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVM--VDGKPVNLGLWDTAGQ 61
            K +++GD  VGKT  +  Y  ++F  +Y  T+  +++  V+   D   + L LWD AGQ
Sbjct: 285 FKVIIIGDPTVGKTSFVQRYVNDSFRRDYKMTIGVDFALKVIRWSDKCNIKLQLWDIAGQ 106

Query: 62  EDYDRLRPLSYPQTDVFLICFSLVSPASFEN 92
           E +  +  + Y      ++ F L    +++N
Sbjct: 105 ERFTSMTRVYYKDAHACIVMFDLTQKNTYQN 13
>36757
          Length = 359

 Score = 50.4 bits (119), Expect = 5e-07,   Method: Compositional matrix adjust.
 Identities = 23/24 (95%), Positives = 24/24 (100%)
 Frame = +2

Query: 152 VKYLECSALTQRGLKTVFDEAIRA 175
           VKYLECSALTQ+GLKTVFDEAIRA
Sbjct: 2   VKYLECSALTQKGLKTVFDEAIRA 73
>27191
          Length = 443

 Score = 50.1 bits (118), Expect = 5e-07,   Method: Compositional matrix adjust.
 Identities = 29/104 (27%), Positives = 53/104 (50%), Gaps = 2/104 (1%)
 Frame = +1

Query: 16  KTCLLISYTTNAFPGEYIPTVFDNYSANVM-VDGKPVNLGLWDTAGQEDYDRLRPLSYPQ 74
           KTCL+  +  + F   Y PTV  +Y   +  V+G  + + +WD +G  +Y  +R   Y  
Sbjct: 1   KTCLIKHFCESKFNQGYQPTVGVDYGFKIQTVNGVDMRVHMWDLSGSNEYLDVRNELYTG 180

Query: 75  TDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPI-ILVGTKL 117
           +D   I F + +  SFE + + W  E+      +P+ ++VG ++
Sbjct: 181 SDAIFIVFDVSNTPSFEALDS-WLREINRFATGSPLNVIVGNRV 309
>33794
          Length = 779

 Score = 49.7 bits (117), Expect = 7e-07,   Method: Compositional matrix adjust.
 Identities = 27/92 (29%), Positives = 47/92 (51%), Gaps = 1/92 (1%)
 Frame = -1

Query: 41  SANVMVDGKPVNLGLWDTAGQEDY-DRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYP 99
           +  ++++GK V L +WDT+GQ  +   +R  S     + L+ + + +  SF+ +  +W  
Sbjct: 680 TTTILLEGKRVKLQIWDTSGQGRFCTIIRSYSRGAQGIILV-YDITNKWSFDGI-DRWLK 507

Query: 100 EVRHHCPNTPIILVGTKLDLRDDKDTIEKLKE 131
           EV  H P  P +LVG +L L   +    K  E
Sbjct: 506 EVEEHAPGIPKVLVGNRLHLAYKRQVAAKQAE 411
>26536
          Length = 829

 Score = 49.3 bits (116), Expect = 9e-07,   Method: Compositional matrix adjust.
 Identities = 37/133 (27%), Positives = 60/133 (45%), Gaps = 2/133 (1%)
 Frame = +2

Query: 45  MVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRA--KWYPEVR 102
           M+  + V+    DTAGQE+Y  +R       D F++ +S+    SF+   A  +W    +
Sbjct: 110 MMMERRVSWTFLDTAGQEEYSSMREHYTRSGDGFIVVYSVTDVTSFQEAEAVFRWLTRFQ 289

Query: 103 HHCPNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQ 162
               +   +L G K DL  D         +K+TP    +G  MA  +G + Y E SA T 
Sbjct: 290 DET-SIHAVLCGNKTDLTSD---------RKVTP---EEGRKMADRLGML-YFETSAKTG 427

Query: 163 RGLKTVFDEAIRA 175
             +  V+   +R+
Sbjct: 428 DNVSQVYHGLLRS 466

 Score = 43.1 bits (100), Expect = 7e-05,   Method: Compositional matrix adjust.
 Identities = 19/46 (41%), Positives = 28/46 (60%)
 Frame = +2

Query: 5   KCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKP 50
           K V++G G VGK+ L I +T + F   Y PT+ D+Y   + V G+P
Sbjct: 491 KIVMLGSGGVGKSSLTIRFTQDTFLDVYDPTIEDSYRKMIQVSGQP 628
>33380
          Length = 282

 Score = 48.9 bits (115), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 26/81 (32%), Positives = 42/81 (51%), Gaps = 1/81 (1%)
 Frame = +3

Query: 44  VMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVR- 102
           V    K V L +WDTAGQE Y  +    Y     F++ + + +  SF  V+  W  +++ 
Sbjct: 39  VFRQDKRVKLQIWDTAGQERYRTITTAYYRGAMGFILMYDVTNEESFNAVQ-DWCTQIKT 215

Query: 103 HHCPNTPIILVGTKLDLRDDK 123
           +   N  ++LVG K DL D++
Sbjct: 216 YSWDNAQVVLVGNKCDLEDER 278
>36482
          Length = 686

 Score = 46.2 bits (108), Expect = 7e-06,   Method: Compositional matrix adjust.
 Identities = 40/142 (28%), Positives = 61/142 (42%), Gaps = 1/142 (0%)
 Frame = +2

Query: 19  LLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVF 78
           L + + T  F GEY PT+   Y  + +++   V L + DTAGQ  Y      +    D F
Sbjct: 2   LTVRFLTRRFIGEYCPTLESVYKYHTVIEDDDVRLEILDTAGQGTYPWKEGYALW-ADCF 178

Query: 79  LICFSLVSPASFEN-VRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTIEKLKEKKLTPI 137
           +  +S+    S+E  V+ K   E      +   +L   K DL  D+             +
Sbjct: 179 VFVYSINDRQSYEELVQVKRQVESVRKSTSLTAVLAANKTDLLHDR------------QV 322

Query: 138 TYPQGLAMAKEIGAVKYLECSA 159
           T  +G  +A+EIG   Y E SA
Sbjct: 323 TQKEGEDLAEEIGCRLY-EVSA 385
>05468
          Length = 1558

 Score = 44.3 bits (103), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 26/95 (27%), Positives = 46/95 (48%), Gaps = 2/95 (2%)
 Frame = -3

Query: 5    KCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVM-VDGKP-VNLGLWDTAGQE 62
            K +V+G+   GKT ++  Y    F   Y  T+  +++  V+  D    + L LWD AGQE
Sbjct: 1535 KILVIGELGTGKTSIIKRYVHQFFSQHYRATIGVDFALKVLNWDADTLIRLQLWDIAGQE 1356

Query: 63   DYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKW 97
             +  +  + Y +     + F +   ++F+ V  KW
Sbjct: 1355 RFGNMTRVYYKEAVGAFVVFDVTRASTFDAV-TKW 1254
>01398
          Length = 1421

 Score = 42.7 bits (99), Expect = 9e-05,   Method: Compositional matrix adjust.
 Identities = 32/110 (29%), Positives = 54/110 (49%), Gaps = 5/110 (4%)
 Frame = -2

Query: 65   DRLRPL--SYPQTDV-FLICFSLVSPASFENVRAKWYPEVRHHC-PNTPIILV-GTKLDL 119
            +R R +  SY +  V  +I + +   ++FEN++ +WY E R+H  P+  I LV G K D 
Sbjct: 1417 ERFRSITRSYYRNSVGVIIVYDITKRSTFENLK-QWYEEARNHIEPHKAIFLVLGHKSDR 1241

Query: 120  RDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVF 169
             D +             +T  +G   A E+  +K+ E SA +   ++ VF
Sbjct: 1240 EDAR------------QVTAREGRRFA-EMHGLKFFETSAKSGHNIEDVF 1130
>00552
          Length = 455

 Score = 40.4 bits (93), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 21/51 (41%), Positives = 31/51 (60%)
 Frame = -3

Query: 54  GLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHH 104
           G+WDTAGQE Y  LR   Y  TD  L+ FS+ +  S +++ + WY E  ++
Sbjct: 150 GIWDTAGQERYKSLRTPFYRGTDCCLLTFSVDNLKSLQSL-SDWYDEFVNY 1

 Score = 36.2 bits (82), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 16/51 (31%), Positives = 31/51 (60%), Gaps = 1/51 (1%)
 Frame = -1

Query: 4   IKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNY-SANVMVDGKPVNL 53
           +K V++GDG VGK+ L+  + +N F  +   T+   + + +V+VDG+   +
Sbjct: 443 LKVVLLGDGGVGKSSLMNRFVSNKFDAQSFHTIGVEFLTKDVVVDGETFTM 291
>09204
          Length = 1051

 Score = 40.4 bits (93), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 26/106 (24%), Positives = 48/106 (45%)
 Frame = -3

Query: 64   YDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDK 123
            Y+ +  + Y      ++CF L   +SF+ +R  W  E+R H     + + GTK DL  D 
Sbjct: 1046 YEAMSRIYYRGAKAAILCFDLTDKSSFDRIRF-WIGELRQHEEECKLYICGTKFDLVHDD 870

Query: 124  DTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVF 169
                   E++  P +  + LA   +    +  E S++T   ++ +F
Sbjct: 869  ------PERRAVPRSVAKALA---DDCMAEIYETSSMTGDNIEKLF 759
>06994
          Length = 429

 Score = 30.4 bits (67), Expect = 0.43,   Method: Compositional matrix adjust.
 Identities = 14/30 (46%), Positives = 19/30 (63%)
 Frame = +1

Query: 31  EYIPTVFDNYSANVMVDGKPVNLGLWDTAG 60
           +Y PT+ D+Y   V VDG+   L + DTAG
Sbjct: 139 KYDPTIEDSYRKQVEVDGQQCMLEILDTAG 228
>14775
          Length = 380

 Score = 30.4 bits (67), Expect = 0.47,   Method: Compositional matrix adjust.
 Identities = 22/69 (31%), Positives = 29/69 (42%), Gaps = 2/69 (2%)
 Frame = -2

Query: 16  KTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNL--GLWDTAGQEDYDRLRPLSYP 73
           KTCLL  Y    F    +PT+    S        P+N+   LWDT G E Y  L    + 
Sbjct: 379 KTCLLRRYQKGFFMDRTMPTIAVLCSEFNESRTDPLNVRYTLWDTGGAETYRSLWVSHFR 200

Query: 74  QTDVFLICF 82
              V L+ +
Sbjct: 199 GAQVALLVY 173
>14139
          Length = 472

 Score = 26.6 bits (57), Expect = 6.3,   Method: Compositional matrix adjust.
 Identities = 19/67 (28%), Positives = 27/67 (40%)
 Frame = +3

Query: 69  PLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTIEK 128
           PLS P T + L+C         + +  K Y     H  N+ I L   K+DL      +E 
Sbjct: 228 PLSXPLTQILLVC------NIAQXIHTKLYAVSESHIHNSYIDLPTPKIDLVYSTQ*VES 389

Query: 129 LKEKKLT 135
           +  K  T
Sbjct: 390 IXSKTYT 410
>23830
          Length = 429

 Score = 26.6 bits (57), Expect = 6.7,   Method: Compositional matrix adjust.
 Identities = 18/60 (30%), Positives = 29/60 (48%), Gaps = 4/60 (6%)
 Frame = -1

Query: 77  VFLICFSLV----SPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTIEKLKEK 132
           V L C+++     S  + ++    W+     HC ++P  L  TKLD R +K   +K K K
Sbjct: 426 VNLTCYNIFNVQSSVXTIQSWAKLWHYXHSLHCTHSPCSLFHTKLD-RQNKHQTKKQKPK 250
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6755382|ref|NP_035434.1| RuvB-like protein 2 [Mus
musculus]
         (463 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

01279                                                                 200   1e-90
23413                                                                 322   2e-88
39786                                                                  70   2e-26
14389                                                                 103   2e-22
23766                                                                  33   0.33 
19129                                                                  31   1.1  
17843                                                                  31   1.3  
07243                                                                  30   1.5  
20339                                                                  29   3.8  
13144                                                                  28   7.5  
>01279
          Length = 2183

 Score =  200 bits (509), Expect(3) = 1e-90,   Method: Compositional matrix adjust.
 Identities = 100/226 (44%), Positives = 154/226 (68%), Gaps = 8/226 (3%)
 Frame = -2

Query: 234  KRKEVVHTVSLHEIDVINSRTQG-------FLALFSGDTGEIKSEVREQINAKVAEWREE 286
            ++KEV+  V+LH++DV N+R QG          L      EI  ++R++IN  V ++ ++
Sbjct: 1417 QKKEVIQDVTLHDLDVANARPQGGQDIMSMMGQLMKPKKTEITDKLRKEINKVVNKYIDQ 1238

Query: 287  GKAEIIPGVLFIDEVHMLDIESFSFLNRALESDMAPVLIMATNRGITRIRGT-SYQSPHG 345
            G AE++PGVLFIDEVHMLDIE F++L+RALES +AP++I ATNRG   I+GT    SPHG
Sbjct: 1237 GIAELVPGVLFIDEVHMLDIECFTYLHRALESTIAPIVIFATNRGKCTIKGTEDIISPHG 1058

Query: 346  IPIDLLDRLLIVSTSPYSEKDTKQILRIRCEEEDVEMSEDAYTVLTRIGLETSLRYAIQL 405
            +P+DLLDR++IV T PYS+++  QIL+IR + E++++ E++   L  IG+ T+LRYA+QL
Sbjct: 1057 MPMDLLDRVMIVRTLPYSQEEMTQILQIRSQTENIQVEEESIQHLGNIGVRTTLRYAVQL 878

Query: 406  ITAASLVCRKRKGTEVQVDDIKRVYSLFLDESRSTQYMKEYQDAFL 451
            +T  S++ R      V  ++I+ +  LF D   S + ++E +D +L
Sbjct: 877  LTPGSILARINGKDNVGKEEIEEIDKLFFDAKASAKILQEQEDKYL 740

 Score =  145 bits (367), Expect(3) = 1e-90,   Method: Compositional matrix adjust.
 Identities = 85/201 (42%), Positives = 118/201 (58%), Gaps = 5/201 (2%)
 Frame = -3

Query: 41   QASQGMVGQLAARRAAGVVLEMIREGKIAGRAVLIAGQPGTGKTAIAMGMAQALGPDTPF 100
            Q+S G+VGQ  AR AAGVV+E+I+  K+AGRAVL+AG PGTGKTAIA+ +AQ LG   PF
Sbjct: 2004 QSSAGLVGQEGAREAAGVVVELIKTKKMAGRAVLLAGPPGTGKTAIALAIAQELGNKVPF 1825

Query: 101  TAIAGSEIFSLEMSKTEALTQAFRRSIGVRXXXXXXX---XXXXXXXXXXDRPATGTGSK 157
              + GSE++S E+ KTE L + FRR+IG+R                    + P  G G  
Sbjct: 1824 CPMVGSEVYSSEIKKTEVLMENFRRAIGLRIKETKEVYEGEVTELTPVETENPMGGYGKT 1645

Query: 158  VGKLT--LKTTEMETIYDLGTKMIESLTKDKVQAGDVITIDKATGKISKLGRSFTRARDY 215
            V  +   LKT +      L   + ESL K+KV+ GDVI I+  +G + + GRS + A ++
Sbjct: 1644 VSHVVIGLKTAKGTKQLKLDPSIYESLQKEKVEVGDVIYIEANSGAVKRQGRSDSYATEF 1465

Query: 216  DAMGSQTKFVQCPDGELQKRK 236
            D    +  +V  P G++ KRK
Sbjct: 1464 DLEAEE--YVPLPKGDVHKRK 1408

 Score = 27.3 bits (59), Expect(3) = 1e-90,   Method: Compositional matrix adjust.
 Identities = 9/16 (56%), Positives = 14/16 (87%)
 Frame = -1

Query: 18   RIERIGAHSHIRGLGL 33
            + +RI +HSH++GLGL
Sbjct: 2072 KAQRIASHSHVKGLGL 2025
>23413
          Length = 2343

 Score =  322 bits (825), Expect = 2e-88,   Method: Compositional matrix adjust.
 Identities = 150/182 (82%), Positives = 170/182 (93%), Gaps = 1/182 (0%)
 Frame = -3

Query: 283  WREEGKAEIIPGVLFIDEVHMLDIESFSFLNRALESDMAPVLIMATNRGITRIRGTSYQS 342
            WREEGKAEI+PGVLFIDEVHMLDIE FSFLNRALE+DMAPVLIMATNRGITRIRGT Y S
Sbjct: 2341 WREEGKAEIVPGVLFIDEVHMLDIECFSFLNRALETDMAPVLIMATNRGITRIRGTHYMS 2162

Query: 343  PHGIPIDLLDRLLIVSTSPYSEKDTKQILRIRCEEEDVEMSEDAYTVLTRIGLETSLRYA 402
            PHG+PIDLLDRLLI+ST+PY EK+ KQIL+IRCEEEDVEMS+DA TVLT+IG+E SLRY+
Sbjct: 2161 PHGVPIDLLDRLLIISTTPYDEKEIKQILKIRCEEEDVEMSDDALTVLTKIGVEASLRYS 1982

Query: 403  IQLITAASLVCRKRKGTEVQVDDIKRVYSLFLDESRSTQYMKEYQDAFLFNELKG-ETMD 461
            IQLITAA+LVCRKRKGTEV+++DIKRVYSLFLDESRSTQ++ EYQ AF+FNE+K  E M+
Sbjct: 1981 IQLITAANLVCRKRKGTEVEMEDIKRVYSLFLDESRSTQFLTEYQQAFMFNEVKDQEQME 1802

Query: 462  TS 463
            TS
Sbjct: 1801 TS 1796
>39786
          Length = 467

 Score = 70.5 bits (171), Expect(2) = 2e-26,   Method: Compositional matrix adjust.
 Identities = 33/41 (80%), Positives = 35/41 (85%)
 Frame = +3

Query: 9   KVPEIRDVTRIERIGAHSHIRGLGLDDALEPRQASQGMVGQ 49
           K  E+RD+TRIERIGAHSHIRGLGLDD LE R  SQGMVGQ
Sbjct: 147 KKYEVRDITRIERIGAHSHIRGLGLDDVLEARAVSQGMVGQ 269

 Score = 66.6 bits (161), Expect(2) = 2e-26,   Method: Compositional matrix adjust.
 Identities = 37/65 (56%), Positives = 47/65 (72%), Gaps = 3/65 (4%)
 Frame = +1

Query: 52  ARRAAGVVLEMIREGKIAGRAVLIAGQPGT---GKTAIAMGMAQALGPDTPFTAIAGSEI 108
           ARRAAGVV++M+REGK   R  L +         K  IA+GMAQALG +TPFT+++GSEI
Sbjct: 277 ARRAAGVVVQMVREGK--NRRTLHSTSRRAEYRKKLPIAVGMAQALGTETPFTSMSGSEI 450

Query: 109 FSLEM 113
           +SLEM
Sbjct: 451 YSLEM 465
>14389
          Length = 790

 Score =  103 bits (256), Expect = 2e-22,   Method: Compositional matrix adjust.
 Identities = 62/169 (36%), Positives = 91/169 (53%), Gaps = 5/169 (2%)
 Frame = +3

Query: 81  TGKTAIAMGMAQALGPDTPFTAIAGSEIFSLEMSKTEALTQAFRRSIGVRXXXXXXX--- 137
           TGKTAIA+ +AQ LG   PF  + GSE+FS E+ KTE L + FRRSIG+R          
Sbjct: 3   TGKTAIALAIAQELGNKVPFCPMVGSEVFSNEIKKTEVLMENFRRSIGLRIRETKEVYEG 182

Query: 138 XXXXXXXXXXDRPATGTGSKVGKLT--LKTTEMETIYDLGTKMIESLTKDKVQAGDVITI 195
                     + P  G G  +  +   LKT +      L   + ++L K+KV+ GDVI I
Sbjct: 183 EVTELTPVETENPMGGYGKTISNVVIGLKTAKGTKQLKLDPSIFDALQKEKVEVGDVIYI 362

Query: 196 DKATGKISKLGRSFTRARDYDAMGSQTKFVQCPDGELQKRKEVVHTVSL 244
           +  +G + + GRS T A ++D    +  +V  P G++ K+KEV+  V+L
Sbjct: 363 EANSGAVKRQGRSDTFATEFDLETEE--YVPLPKGDVHKKKEVIQDVTL 503

 Score = 73.6 bits (179), Expect = 1e-13,   Method: Compositional matrix adjust.
 Identities = 33/87 (37%), Positives = 58/87 (66%)
 Frame = +3

Query: 362 YSEKDTKQILRIRCEEEDVEMSEDAYTVLTRIGLETSLRYAIQLITAASLVCRKRKGTEV 421
           YS  D +QI+++R + E +++ E+A++ L+ IG  ++LRYA+QL+T A  +C+      +
Sbjct: 507 YSTSDMEQIIKLRAQTEGLQLEENAFSRLSEIGTSSTLRYAVQLLTPAYQMCKVNGRNLI 686

Query: 422 QVDDIKRVYSLFLDESRSTQYMKEYQD 448
             DDI  V+SLFLD  RS++++ E  +
Sbjct: 687 SKDDIDDVHSLFLDAKRSSKHLSEKNN 767
>23766
          Length = 1463

 Score = 32.7 bits (73), Expect = 0.33,   Method: Compositional matrix adjust.
 Identities = 17/46 (36%), Positives = 25/46 (54%)
 Frame = +1

Query: 64  REGKIAGRAVLIAGQPGTGKTAIAMGMAQALGPDTPFTAIAGSEIF 109
           R+G  A + V++ G PGTGKT +A  +A        F  + GSE+ 
Sbjct: 136 RDGNQAPKGVILYGPPGTGKTLLAKAVANQTS--ATFLRVVGSELI 267
>19129
          Length = 1020

 Score = 30.8 bits (68), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 15/38 (39%), Positives = 23/38 (60%)
 Frame = +1

Query: 71  RAVLIAGQPGTGKTAIAMGMAQALGPDTPFTAIAGSEI 108
           + VL+ G PGTGKT +A  +A     +  F  ++GSE+
Sbjct: 592 KGVLLYGPPGTGKTLLARAVAHHT--ECTFIRVSGSEL 699
>17843
          Length = 772

 Score = 30.8 bits (68), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 11/25 (44%), Positives = 15/25 (60%)
 Frame = +1

Query: 70  GRAVLIAGQPGTGKTAIAMGMAQAL 94
            R +L+ G PGTGKT +   +A  L
Sbjct: 184 NRVILLHGPPGTGKTTLCKALAHKL 258
>07243
          Length = 1112

 Score = 30.4 bits (67), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 17/47 (36%), Positives = 23/47 (48%)
 Frame = +1

Query: 62  MIREGKIAGRAVLIAGQPGTGKTAIAMGMAQALGPDTPFTAIAGSEI 108
            +R G    +  L+ G PGTGKT +A  +A  L  D  F  +  S I
Sbjct: 283 FLRVGITPPKGCLLYGPPGTGKTLLARAVASQL--DANFLKVVSSAI 417
>20339
          Length = 470

 Score = 29.3 bits (64), Expect = 3.8,   Method: Compositional matrix adjust.
 Identities = 19/58 (32%), Positives = 28/58 (48%)
 Frame = +2

Query: 155 GSKVGKLTLKTTEMETIYDLGTKMIESLTKDKVQAGDVITIDKATGKISKLGRSFTRA 212
           G + G L+LKT     + DL  K+IESL        D   I++   K+ K+   F R+
Sbjct: 281 GFQKGALSLKTATQSAVLDLLKKLIESLLVCSEFCFDFFVIEQ---KLQKIPSXFKRS 445
>13144
          Length = 457

 Score = 28.1 bits (61), Expect = 7.5,   Method: Composition-based stats.
 Identities = 9/31 (29%), Positives = 21/31 (67%)
 Frame = +1

Query: 154 TGSKVGKLTLKTTEMETIYDLGTKMIESLTK 184
           +GS++GK+ ++ ++ E  +  GTK++E   +
Sbjct: 283 SGSQIGKINIRASQQEEFFAHGTKLLEPFEQ 375
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|70794809|ref|NP_001020566.1| Rous sarcoma oncogene
isoform 2 [Mus musculus]
         (535 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

21808                                                                 327   8e-90
06405                                                                 303   2e-82
11780                                                                 204   1e-71
09007                                                                 151   6e-37
04852                                                                 150   2e-36
17300                                                                 127   2e-34
07291                                                                 130   2e-30
14116                                                                 127   2e-29
20640                                                                 125   4e-29
07940                                                                 116   3e-26
18996                                                                 100   2e-21
08294                                                                 100   2e-21
14477                                                                  94   1e-19
13592                                                                  92   4e-19
17637                                                                  92   7e-19
01718                                                                  88   9e-18
01756                                                                  86   3e-17
19301                                                                  86   5e-17
00715                                                                  84   2e-16
22005                                                                  84   2e-16
13305                                                                  77   2e-14
17253                                                                  76   3e-14
07833                                                                  75   6e-14
12721                                                                  74   1e-13
18921                                                                  72   8e-13
01060                                                                  70   2e-12
00300                                                                  70   2e-12
29581                                                                  69   4e-12
01707                                                                  66   4e-11
04591                                                                  65   8e-11
27546                                                                  64   1e-10
14126                                                                  64   1e-10
14420                                                                  62   5e-10
31885                                                                  60   2e-09
01966                                                                  59   5e-09
03240                                                                  59   7e-09
09606                                                                  59   7e-09
13066                                                                  58   8e-09
18484                                                                  58   9e-09
07836                                                                  58   1e-08
13212                                                                  57   2e-08
25550                                                                  56   3e-08
12672                                                                  56   3e-08
28157                                                                  55   6e-08
04138                                                                  54   1e-07
11228                                                                  52   6e-07
19761                                                                  51   9e-07
21079                                                                  50   3e-06
14257                                                                  50   3e-06
21210                                                                  49   5e-06
30755                                                                  49   5e-06
06462                                                                  48   1e-05
19094                                                                  47   2e-05
29243                                                                  47   2e-05
26560                                                                  46   3e-05
12324                                                                  46   3e-05
37602                                                                  46   4e-05
15910                                                                  45   5e-05
11185                                                                  45   7e-05
32264                                                                  44   2e-04
16708                                                                  41   0.001
27405                                                                  41   0.001
29687                                                                  41   0.001
16716                                                                  41   0.001
05206                                                                  40   0.002
32000                                                                  40   0.002
35671                                                                  40   0.002
18881                                                                  40   0.002
26711                                                                  40   0.002
18481                                                                  39   0.004
12786                                                                  39   0.004
28638                                                                  39   0.005
38046                                                                  39   0.007
28095                                                                  37   0.014
29636                                                                  37   0.014
07933                                                                  37   0.014
21433                                                                  36   0.030
01392                                                                  36   0.033
13641                                                                  36   0.034
36481                                                                  36   0.035
01494                                                                  36   0.036
30740                                                                  36   0.037
17286                                                                  36   0.048
17516                                                                  35   0.051
20152                                                                  34   0.14 
13664                                                                  34   0.19 
37260                                                                  32   0.43 
27287                                                                  32   0.58 
29360                                                                  32   0.73 
02638                                                                  30   2.0  
23319                                                                  30   2.9  
32357                                                                  30   3.2  
15741                                                                  29   4.9  
30231                                                                  29   5.9  
28929                                                                  28   7.2  
>21808
          Length = 1011

 Score =  327 bits (838), Expect = 8e-90,   Method: Compositional matrix adjust.
 Identities = 155/225 (68%), Positives = 183/225 (81%), Gaps = 1/225 (0%)
 Frame = +1

Query: 286 GTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVS-EEPIYIVTEYMN 344
           G WN TT VAIKTLK GTM P+ FL EAQ+MKKLRH KL+QLYAV + ++PI+I+TE M 
Sbjct: 4   GLWNNTTPVAIKTLKSGTMDPKDFLAEAQIMKKLRHPKLIQLYAVCTQDDPIFIITELMK 183

Query: 345 KGSLLDFLKGETGKYLRLPQLVDMSAQIASGMAYVERMNYVHRDLRAANILVGENLVCKV 404
            GSLL+FL+G+ G+ L+LP L+D+ AQIA GMAY+E  NY+HRDL A NILV +N   K+
Sbjct: 184 NGSLLEFLQGK-GRVLKLPALIDIGAQIACGMAYLESQNYIHRDLAARNILVSDNNTVKI 360

Query: 405 ADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVP 464
           ADFGLAR+I+++EY AR GA+FPIKWTAPEAA Y RFTIKSDVWSFGILLTE  T GRVP
Sbjct: 361 ADFGLARVIKEDEYEARVGARFPIKWTAPEAANYNRFTIKSDVWSFGILLTETVTYGRVP 540

Query: 465 YPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKEPEERP 509
           YPGM N EVL QVE GYRMPCPP CP+ L+D+M +CWRKE  ERP
Sbjct: 541 YPGMTNAEVLHQVEHGYRMPCPPGCPKPLYDIMLECWRKEEMERP 675
>06405
          Length = 1965

 Score =  303 bits (775), Expect = 2e-82,   Method: Compositional matrix adjust.
 Identities = 161/350 (46%), Positives = 226/350 (64%), Gaps = 5/350 (1%)
 Frame = +1

Query: 178 ESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHAD 237
           ESE++ G   +SV  F+      V HY+I + D G  ++T   +FN+L +LV ++S HAD
Sbjct: 1   ESESSPGQRSISVR-FEG----RVYHYRITE-DDGKVFVTQEHRFNTLAELVHHHSIHAD 162

Query: 238 GLCHRLTTVCPT-SKPQTQGLAK--DAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTR- 293
           GL   L    P   KP   G++   D WEI R  + ++ +LG G +G+V+   W    + 
Sbjct: 163 GLVTTLLYPAPKRQKPTVFGVSPEPDRWEIERTEIAMKHRLGGGQYGDVYEAMWKRYNKI 342

Query: 294 VAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEP-IYIVTEYMNKGSLLDFL 352
           VA+KTLK  TM+   FL+EA +MK+++H  LVQL  V + EP  YIVTE+M  G+LLD+L
Sbjct: 343 VAVKTLKEDTMALNDFLEEAAIMKEMKHPNLVQLLGVCTREPPFYIVTEFMPHGNLLDYL 522

Query: 353 KGETGKYLRLPQLVDMSAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARL 412
           +  T +      L+ M+ QIASGMAY+E  N++HRDL A N LV ++ + KVADFGLARL
Sbjct: 523 RSSTREENGPTALMYMATQIASGMAYLETKNFIHRDLAARNCLVADSNMVKVADFGLARL 702

Query: 413 IEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNRE 472
           ++D+ YTA  GAKFPIKWTAPE   + RF+ +SD+W+FG+LL EL T G  PYPG+   E
Sbjct: 703 MKDDTYTAHIGAKFPIKWTAPEGLAFNRFSTRSDIWAFGVLLWELATYGMSPYPGVELTE 882

Query: 473 VLDQVERGYRMPCPPECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYF 522
           V   +ERGYRM  PP  P  ++ LM +CW+ +P++RPTF+ +   LE+ F
Sbjct: 883 VYHLLERGYRMERPPGTPADVYILMLKCWQWDPKDRPTFKEIHFLLENMF 1032
>11780
          Length = 1713

 Score =  204 bits (519), Expect(2) = 1e-71,   Method: Compositional matrix adjust.
 Identities = 130/347 (37%), Positives = 183/347 (52%), Gaps = 15/347 (4%)
 Frame = +3

Query: 104 FKKGERLQIVNNTEGDWWLAHSLSTGQTGYIPSNYVAPSD--SIQAEEWYFGKITRRESE 161
           F+KG+ L I   T    W     S G+ G IP+NYV P    ++ A  W+ GKITR+++E
Sbjct: 111 FQKGDLLVIRRATSDRMWYKACDSNGREGMIPANYVQPRKVVTLHAMPWFHGKITRQQAE 290

Query: 162 RLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIR------KLDSGGFY 215
            LL   E+  G FL+RES    G Y L V          V+HY+I        +D  GF 
Sbjct: 291 ELLKPRED--GLFLIRESSNYPGDYTLCVCHLGK-----VEHYRILYRENQLTIDEEGF- 446

Query: 216 ITSRTQFNSLQQLVAYYSKHADGLCHRLTTVCPTSKP-------QTQGLAKDAWEIPRES 268
                 F +L +LV +Y   ADGLC +LT   P +K          Q      W I  + 
Sbjct: 447 ------FRNLDELVKHYLADADGLCTQLTR--PVTKQGGNFGTVSLQEFKSGGWVIAXQD 602

Query: 269 LRLEVKLGQGCFGEVWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLY 328
           L +   +G+G FG+V+ G + G   VAIK LK      ++FLQEA VM  LRH+ LV+L 
Sbjct: 603 LEIGEAIGKGDFGDVYKGMYRGQP-VAIKQLKDKDRGEQSFLQEASVMTSLRHDNLVRLI 779

Query: 329 AVVSEEPIYIVTEYMNKGSLLDFLKGETGKYLRLPQLVDMSAQIASGMAYVERMNYVHRD 388
            VV  E I++VTE+M KG+L+++L+      +     ++ +    + M Y+E    VHRD
Sbjct: 780 GVVLGETIFLVTEFMGKGNLVEYLRSRGRSVITKKDQINFATDTCAAMEYLESKRLVHRD 959

Query: 389 LRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEA 435
           L A N+LV ++   KV+DFGLA+  +     ++   KFPIKWTAPEA
Sbjct: 960 LAARNVLVHDDGKAKVSDFGLAKFGD----FSQTSVKFPIKWTAPEA 1088

 Score = 85.1 bits (209), Expect(2) = 1e-71,   Method: Compositional matrix adjust.
 Identities = 41/81 (50%), Positives = 55/81 (67%)
 Frame = +1

Query: 440  RFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQ 499
            +FT KSD+WSFGILL E+ + GRVPYP +   +V+  VERGYRM  P  CP  ++ +M Q
Sbjct: 1102 KFTSKSDMWSFGILLWEIYSFGRVPYPRIPLTDVVMHVERGYRMEAPEGCPPEIYSIMKQ 1281

Query: 500  CWRKEPEERPTFEYLQAFLED 520
             W  +P ERPTF+ + A L +
Sbjct: 1282 AWELDPNERPTFKSVLARLNN 1344
>09007
          Length = 1440

 Score =  151 bits (382), Expect = 6e-37,   Method: Compositional matrix adjust.
 Identities = 97/283 (34%), Positives = 150/283 (53%), Gaps = 15/283 (5%)
 Frame = -1

Query: 264 IPRESLRLEVKLGQGCFGEVWMGTWNGTT----RVAIKTLKPGTMSPEA--FLQEAQVMK 317
           I ++ + L   LGQG FG V    W   +    +VA+K L    +  +   FL+E  +M+
Sbjct: 888 ISKDCVALSKSLGQGHFGTVRQAIWTAESGEKVQVAVKCLSKDKIHKDGQEFLKETAIMQ 709

Query: 318 KLRHEKLVQLYAVVSEE--PIYIVTEYMNKGSLLDFLKGETGKY-LRLPQLVDMSAQIAS 374
            L HE +V++Y VV +    I +VTE     SLL+ +K  + +    +P+L D S Q+  
Sbjct: 708 MLDHENIVRVYGVVMDNGADIMLVTELAPMRSLLECVKEVSARVDFSVPRLCDFSQQVCD 529

Query: 375 GMAYVERMNYVHRDLRAANILVGENLVCKVADFGLA-RLIEDNEYTARQGA---KFPIKW 430
           GM+Y+E    VHRDL A NIL+      K++D G++  L    EY   Q     +  + W
Sbjct: 528 GMSYLESKRLVHRDLAARNILLFSKSKVKISDVGVSGALGAGKEYYQSQQTIHLQNAVAW 349

Query: 431 TAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVE--RGYRMPCPPE 488
            APE+     F+  SDVW+FG+LL E  T G  P+ G+  +++++ V+  +  R+  P  
Sbjct: 348 CAPESFRNLCFSSASDVWAFGVLLWEFFTHGFQPWAGLNGQQIMEAVDAPQSQRLEQPDL 169

Query: 489 CPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYFTSTEPQYQP 531
           CP+  + +M +CW +EP+ RPTF   Q FL      T PQ +P
Sbjct: 168 CPKEYYAVMLKCWEQEPQRRPTFS--QLFL------TLPQIRP 64
>04852
          Length = 1462

 Score =  150 bits (378), Expect = 2e-36,   Method: Compositional matrix adjust.
 Identities = 88/263 (33%), Positives = 135/263 (51%), Gaps = 31/263 (11%)
 Frame = +1

Query: 294 VAIKTLKPGTMSPEA--FLQEAQVMKKLR----HEKLVQLYAVVSEE-PIYIVTEYMNKG 346
           VA+K L+    + E   F+QE QVMK ++    H  +V      ++  P++++ E+   G
Sbjct: 28  VAVKMLRDIVTAVEEQDFVQELQVMKAVKKMGSHINIVNFLGCCTQGGPLWVIVEFAKNG 207

Query: 347 SLLDFL-----------------------KGETGKYLRLPQLVDMSAQIASGMAYVERMN 383
           +L DFL                       K   G  +R   L+  + QIA GM ++    
Sbjct: 208 NLRDFLESCRDGINGYGKFVSPQDPGWYTKTPGGHVIRRKNLLSYAFQIARGMEFLASRK 387

Query: 384 YVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTI 443
            +HRDL A N+LV E  V K+ADFGL+R    + Y  R G + P+KW APEA    R+T 
Sbjct: 388 CIHRDLAARNVLVTEEHVLKIADFGLSR--TGDYYKKRSGGRLPVKWMAPEALFDMRYTT 561

Query: 444 KSDVWSFGILLTELTTKGRVPYPGMVNREVLDQ-VERGYRMPCPPECPESLHDLMCQCWR 502
           KSDVWSFG++L E+ + G +PY  + N E+  + ++  YRMP P     +L+ +M +CW 
Sbjct: 562 KSDVWSFGVVLWEIFSLGGMPYASIPNEELYSKLLDDAYRMPRPELASGNLYAIMERCWL 741

Query: 503 KEPEERPTFEYLQAFLEDYFTST 525
             P +RP F  L   ++    ++
Sbjct: 742 NRPSDRPEFSQLVGHIDRLLMTS 810
>17300
          Length = 480

 Score =  127 bits (320), Expect(2) = 2e-34,   Method: Compositional matrix adjust.
 Identities = 63/117 (53%), Positives = 81/117 (69%), Gaps = 4/117 (3%)
 Frame = +1

Query: 372 IASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDN----EYTARQGAKFP 427
           I+SGM  +  M YVHRDL A NILV E LVCKVADFGL+R IE +     YT + G K P
Sbjct: 1   ISSGMGXLADMGYVHRDLAARNILVNEILVCKVADFGLSREIESDTTEGAYTTK-GGKIP 177

Query: 428 IKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMP 484
           ++WTAPEA  Y +FT  SDVWSFG+++ E+ + G  PY    N++V+  VE+GYR+P
Sbjct: 178 VRWTAPEAIAYRKFTSASDVWSFGVVMWEVMSYGERPYWNWSNQDVIKAVEKGYRLP 348

 Score = 36.6 bits (83), Expect(2) = 2e-34,   Method: Composition-based stats.
 Identities = 16/43 (37%), Positives = 22/43 (51%), Gaps = 1/43 (2%)
 Frame = +2

Query: 485 CPP-ECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYFTSTE 526
           CP  +CPE+LH LM   W+KE   RP    +   L+    + E
Sbjct: 344 CPSMDCPEALHQLMLDAWQKERSHRPKMSMVVKTLDKLIRAPE 472
>07291
          Length = 833

 Score =  130 bits (326), Expect = 2e-30,   Method: Compositional matrix adjust.
 Identities = 66/167 (39%), Positives = 101/167 (60%), Gaps = 2/167 (1%)
 Frame = +1

Query: 357 GKYLRLPQLVDMSAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLA-RLIED 415
            K L + QL+D   QIA GMAY++ +  VHR+L A N +V E+   +++D+G+   L   
Sbjct: 31  SKMLTVVQLLDFGRQIADGMAYLQEVKVVHRNLAARNCIVTEDGRLQLSDYGVTGSLFPQ 210

Query: 416 NEYTARQG-AKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVL 474
           + YTA    A+  +KW APE      F+ KSDVW+FG++L EL T+G  PYP + N  +L
Sbjct: 211 SYYTADDSPARDLVKWMAPETIDNFHFSSKSDVWAFGVVLWELLTRGITPYPDVENSSLL 390

Query: 475 DQVERGYRMPCPPECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDY 521
             ++ G+RM  P + PE ++++M  CW + PE+RP F  L   L+ +
Sbjct: 391 PYLKEGHRMKKPKQSPEPVYEMMTACWNESPEQRPDFAELNDQLKTF 531
>14116
          Length = 1017

 Score =  127 bits (318), Expect = 2e-29,   Method: Compositional matrix adjust.
 Identities = 78/216 (36%), Positives = 119/216 (55%), Gaps = 13/216 (6%)
 Frame = -1

Query: 264 IPRESLRLEVKLGQGCFGEVWMGTWN-----GTTRVAIKTL---KPGTMSPEAFLQEAQV 315
           I RE L +  ++G+G FG V  G        G   VA+KTL    P  +  ++FLQEA +
Sbjct: 645 IDREFLTMGEEIGKGNFGCVKRGFLTLPEQKGDILVAVKTLHNNNPREIELQSFLQEALI 466

Query: 316 MKKLRHEKLVQLYAV---VSEEPIYIVTEYMNKGSLLDFLKGETGKYLRLPQLVDMSAQI 372
           MK   H  ++ L  +   + + P+ +V  +M  G LL +++ +  +   +  L+     I
Sbjct: 465 MKDFHHSNVLTLIGICLNLDDMPL-VVLPFMKHGDLLTYIRDDQHQP-TIKDLIMYGVDI 292

Query: 373 ASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQG--AKFPIKW 430
           A GM Y+  + +VHRDL A N ++ E+   KVADFGLAR I + EY + +   AK P+KW
Sbjct: 291 ARGMDYLAGLKFVHRDLAARNCMLDEDFHVKVADFGLARDIYEKEYYSSENKKAKLPVKW 112

Query: 431 TAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYP 466
            A E+   G +  K+DVWS+G++L EL T+G    P
Sbjct: 111 MALESLEKGNYDSKTDVWSYGVVLWELLTRGSDALP 4
>20640
          Length = 1492

 Score =  125 bits (314), Expect = 4e-29,   Method: Compositional matrix adjust.
 Identities = 60/144 (41%), Positives = 85/144 (59%), Gaps = 1/144 (0%)
 Frame = +1

Query: 384 YVHRDLRAANILVGENLVCKVADFGLARLIED-NEYTARQGAKFPIKWTAPEAALYGRFT 442
           YVHRDL   N LVG +LV K++DFGLAR +   + Y   +    PI+W   EA LY +F+
Sbjct: 7   YVHRDLATRNCLVGHDLVVKISDFGLARSVHSVDYYRGSEHDAIPIRWMPLEAILYNKFS 186

Query: 443 IKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWR 502
            +SDVWSFG++L E+      PY G+ + EV+  V+ G  + CP   P  +++LM QCW 
Sbjct: 187 TQSDVWSFGVVLWEIFAFALQPYYGLTHEEVVRFVKEGKVLACPERTPPPMYELMKQCWH 366

Query: 503 KEPEERPTFEYLQAFLEDYFTSTE 526
           + P  RP+F  L   LE+  +  E
Sbjct: 367 RRPATRPSFHTLHKTLENMHSKYE 438
>07940
          Length = 1336

 Score =  116 bits (290), Expect = 3e-26,   Method: Compositional matrix adjust.
 Identities = 84/277 (30%), Positives = 126/277 (45%), Gaps = 70/277 (25%)
 Frame = -3

Query: 262 WEIPRESLRLEVKLGQGCFGEVW----MGTW--NGTTRVAIKTLKPGTMSPEA--FLQEA 313
           WE PRE L L  +LG+G FG V     MG +  N +  VA+K LK      E    ++E 
Sbjct: 857 WEFPRERLVLGDRLGEGAFGLVMKGEAMGIFKDNNSVTVAVKMLKEDATDREMMDLIREM 678

Query: 314 QVMKKL-RHEKLVQLYAVVSEE-PIYIVTEYM---------------------------- 343
           ++MK + +H+ ++ L    ++   +Y++ E+                             
Sbjct: 677 EMMKVIGKHKNIINLLGCCTQRGALYVIVEFAPHGNLRDFLKSHRPHGTSYSCIADYEQP 498

Query: 344 ------------------NKGSLLDFLKG------ETG-------KYLRLPQLVDMSAQI 372
                              +G+ L F+ G       TG       K L    L+  + Q+
Sbjct: 497 VITSSSSSFSHPNSASSSAQGTSLGFIPGTSTVSFSTGSHRQDMLKMLTPKDLISYAYQV 318

Query: 373 ASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQ-GAKFPIKWT 431
           A GM Y+     +HRDL A N+LV E  V K+ADFGL R ++  +Y  +    + P+KW 
Sbjct: 317 ARGMEYLASKQCIHRDLAARNVLVAEEYVLKIADFGLTRNLQQFDYYRKTTDGRLPVKWM 138

Query: 432 APEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGM 468
           APEA    ++T KSDVWS+G+LL E+ T G  PYP +
Sbjct: 137 APEALFDRKYTSKSDVWSYGVLLWEIFTLGGNPYPSV 27
>18996
          Length = 491

 Score = 99.8 bits (247), Expect = 2e-21,   Method: Compositional matrix adjust.
 Identities = 54/136 (39%), Positives = 81/136 (59%), Gaps = 6/136 (4%)
 Frame = +2

Query: 385 VHRDLRAANILVGENLVCKVADFGLARLIE-DNEYTARQGAKFPIKWTAPEAALYGRFTI 443
           +HRDL A NILV  + V K++DFGLA+    D  Y        PIKW +PEA    +F+ 
Sbjct: 2   IHRDLAARNILVDRSCV-KISDFGLAQFANADGYYYGISQRDIPIKWYSPEAIETCKFSS 178

Query: 444 KSDVWSFGILLTELTTKGRVP--YPG--MVNREVLDQVERGYRMPCPPECPESLH-DLMC 498
            SDVWS+G+ L E+ ++G +P   PG  +   E L+++ +G R+P P  C + ++ +LM 
Sbjct: 179 YSDVWSYGVTLFEMFSRGEIPNLLPGHDLTQEEFLNRLRKGERLPKPELCSDFVYSELMR 358

Query: 499 QCWRKEPEERPTFEYL 514
            CW + P+ RPTF  +
Sbjct: 359 PCWHEMPKSRPTFHQI 406
>08294
          Length = 1849

 Score = 99.8 bits (247), Expect = 2e-21,   Method: Compositional matrix adjust.
 Identities = 63/207 (30%), Positives = 97/207 (46%), Gaps = 11/207 (5%)
 Frame = +2

Query: 323  KLVQLYAVVSE-EPIYIVTEYMNKGSLLDFL----------KGETGKYLRLPQLVDMSAQ 371
             +V    V  E EP +++TEY + G L  FL          +G     L L Q + M  Q
Sbjct: 890  NIVHFMGVCREAEPHFLITEYCDWGDLKQFLLATRNDNGRGRGTRVPALALSQKLGMGQQ 1069

Query: 372  IASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKWT 431
            +A+GM  +     VH DL A N+L+   +  KVA   L+  +  +EY        P++W 
Sbjct: 1070 VAAGMEALSNQGLVHGDLAARNVLLTSRMQLKVARPALSGDVYASEYYPLHQRLVPLRWL 1249

Query: 432  APEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPECPE 491
             PE  L    T   DVW+FG+ L E+     +PY  M + EVL  ++        P+ P 
Sbjct: 1250 PPEGVLEDSATTCGDVWAFGVFLWEVLQLADLPYRLMSDEEVLRSLQHSQAALDSPDAPP 1429

Query: 492  SLHDLMCQCWRKEPEERPTFEYLQAFL 518
            +L  L+ +C  ++P +RP F  + + L
Sbjct: 1430 ALLSLLQRCTAQQPSQRPPFSEICSVL 1510
>14477
          Length = 493

 Score = 94.0 bits (232), Expect = 1e-19,   Method: Composition-based stats.
 Identities = 58/160 (36%), Positives = 89/160 (55%), Gaps = 8/160 (5%)
 Frame = -1

Query: 272 EVKLGQGCFGEVWMGTWNGTTR---VAIKTLKPGTMSPEA---FLQEAQVMKKLRHEKLV 325
           E+KLG G FG V  G      R   VAIK LK   + P      ++EA+VMKK+ H  +V
Sbjct: 475 ELKLGAGNFGSVMKGVCRLDDREIPVAIKVLKNADLDPSVQSELIKEAEVMKKMDHMHIV 296

Query: 326 QLYAVVSEEPIYIVTEYMNKGSLLDFLKGETGKYLRLPQLVDMSAQIASGMAYVERMNYV 385
           +L  +   E + +V E    G L  FL     K+L L  ++++  Q++ GM Y+E   +V
Sbjct: 295 RLIGLCEGETMMLVLELAKLGPLNKFLP--KNKHLPLWNILELMWQVSQGMEYLEANKFV 122

Query: 386 HRDLRAANILVGENLVCKVADFGLARLI--EDNEYTARQG 423
           HRDL A NIL+ +    K++DFG+++ +  E+N Y A++ 
Sbjct: 121 HRDLAARNILLCDEHFAKISDFGMSKTLSRENNYYMAQEA 2
>13592
          Length = 980

 Score = 92.4 bits (228), Expect = 4e-19,   Method: Compositional matrix adjust.
 Identities = 74/257 (28%), Positives = 135/257 (52%), Gaps = 21/257 (8%)
 Frame = +2

Query: 273 VKLGQGCFGEVWMGTWNGTTRV-AIK--TLKPG-TMSPEAFLQEAQVMKKLRHEKLVQLY 328
           +K+GQG FG+V+    N T  + A+K   ++PG T + +   +E ++++ ++H+ LV+ Y
Sbjct: 2   IKIGQGRFGKVYTAVNNNTGELMAMKEIAIQPGETRALKNVAEELKILEGIKHKNLVRYY 181

Query: 329 AV-VSEEPIYIVTEYMNKGSLLDFLKGETGKYLRLPQLVD--MSAQIASGMAYVERMNYV 385
            + V  E + I  E  ++G+L   ++   G    LP+ +    +AQ+ SG+A + +   V
Sbjct: 182 GIEVHREELLIFMELCSEGTLESLVELTGG----LPEALSRRFTAQLLSGVAELHKHGIV 349

Query: 386 HRDLRAANI-LVGENLVCKVADFGLARLIEDNE--------YTARQGAKFPIKWTAPEAA 436
           HRD++ ANI LV  +   K+ DFG A  I+ +         Y   Q    P  +T   + 
Sbjct: 350 HRDIKTANIFLVDGSNSLKLGDFGSAVKIQAHTTVPGELQGYVGTQAYMAPEVFTKTNSD 529

Query: 437 LYGRFTIKSDVWSFGILLTELTTKGRVPYPGM-VNREVLDQVERGYRMPCPPECPESL-- 493
            +GR    +D+WS G ++ E+ + G+ P+     N +++ +V  G +    P+ PESL  
Sbjct: 530 GHGRL---ADIWSVGCVVVEMAS-GKRPWAQFDSNFQIMFKVGMGEK----PQAPESLSQ 685

Query: 494 --HDLMCQCWRKEPEER 508
             HD +  C + +P++R
Sbjct: 686 EGHDFIDHCLQHDPKQR 736
>17637
          Length = 447

 Score = 91.7 bits (226), Expect = 7e-19,   Method: Compositional matrix adjust.
 Identities = 46/132 (34%), Positives = 72/132 (54%), Gaps = 1/132 (0%)
 Frame = +1

Query: 393 NILVGENLVCKVADFGLARLIEDNEYTARQGAKF-PIKWTAPEAALYGRFTIKSDVWSFG 451
           N ++ + L  K+ D  L+R +   +Y      ++ PIKW + EA     +   SDVWSFG
Sbjct: 1   NCVIDDQLRVKLTDSALSRDLFSGDYNCLGDGEYRPIKWLSLEALQKSHYNEGSDVWSFG 180

Query: 452 ILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKEPEERPTF 511
           +L+ E+ T G++PY  +   E+   ++ GYR+  P  CP+ L  +M  CW   P ERP+F
Sbjct: 181 VLMWEMCTLGKLPYAEIDPYEMEHYLKDGYRLAQPFNCPDELFTIMAYCWASMPAERPSF 360

Query: 512 EYLQAFLEDYFT 523
             LQ  L ++ T
Sbjct: 361 SQLQICLSEFHT 396
>01718
          Length = 959

 Score = 87.8 bits (216), Expect = 9e-18,   Method: Compositional matrix adjust.
 Identities = 77/265 (29%), Positives = 128/265 (48%), Gaps = 14/265 (5%)
 Frame = +3

Query: 274 KLGQGCFGEVWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAV-VS 332
           K+G G F EV+  T   T +V    +   T +    L+E Q++ +L+H  +++   V V 
Sbjct: 168 KIGAGFFSEVFKVTHRITGQVMALKMNTMTSNRHNMLREVQLLNRLQHANILRFMGVCVH 347

Query: 333 EEPIYIVTEYMNKGSLLDFLKGETGKYLRLPQLVDMSAQIASGMAYVERMNYVHRDLRAA 392
           E  ++ +TEY+  G+L   L+ +  + L   Q + ++  +A G+ Y+    ++HRDL + 
Sbjct: 348 EGQLHALTEYIPSGNLEQLLE-KKDEELPWTQRIQLTLGLARGLDYLHSTRFIHRDLTSK 524

Query: 393 NILV----GENLVCKVADFGLARLIE---DNEYTARQGAKFPIKWTAPEAALYGRF-TIK 444
           NIL+           +ADFGLA  I    D E     G+ +   W APE  L G F   +
Sbjct: 525 NILIRREDNHGYHAVIADFGLATKIPDPLDKEKLPTVGSPY---WMAPE-VLNGHFYNER 692

Query: 445 SDVWSFGILLTELTTKGRVP-----YPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQ 499
           +D++S GI++ E+T   R+P      P M N  V D V     +     CP     L  +
Sbjct: 693 ADLFSVGIIMCEIT--ARIPADPDIMPRMNNFGV-DYVALSEMI---SYCPLDYLQLAFK 854

Query: 500 CWRKEPEERPTFEYLQAFLEDYFTS 524
           C + +P++RP    +  +LE  F +
Sbjct: 855 CCQVDPQKRPRGVEIIEWLEKIFKN 929
>01756
          Length = 1858

 Score = 86.3 bits (212), Expect = 3e-17,   Method: Compositional matrix adjust.
 Identities = 63/212 (29%), Positives = 99/212 (46%), Gaps = 22/212 (10%)
 Frame = -3

Query: 274  KLGQGCFGEVWMGTWNGTTRVAIKTLKPGTMS------PEAFLQEAQVMKKLRHEKLVQL 327
            K+GQG FGEV+      T +V    +K   M       P   L+E ++++ L HE +V L
Sbjct: 1721 KIGQGTFGEVFKARCKKTKQVV--AMKKVLMDNEKEGFPITALREIKILQLLNHENVVDL 1548

Query: 328  YAVVSEEP---------IYIVTEYMNKGSLLDFLKGETGKYLRLPQLVDMSAQIASGMAY 378
              + S +           Y+V E+      L  L         LP++ ++  Q+ +G+ Y
Sbjct: 1547 IEICSTKATSANRYKSMFYLVFEFCEHD--LAGLLSNMSVVFNLPEIKEVMKQLMNGLYY 1374

Query: 379  VERMNYVHRDLRAANILVGENLVCKVADFGLAR-----LIEDNEYTARQGAKFPIKWTAP 433
            + R   +HRD++AANIL+ +  V K+ADFGLAR     L + N YT R        W  P
Sbjct: 1373 IHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNR----VVTLWYRP 1206

Query: 434  EAALYG--RFTIKSDVWSFGILLTELTTKGRV 463
               L G   ++   D W  G ++ E+ T+  +
Sbjct: 1205 PELLLGDRNYSTAIDQWGAGCIMAEMWTRNPI 1110
>19301
          Length = 712

 Score = 85.5 bits (210), Expect = 5e-17,   Method: Compositional matrix adjust.
 Identities = 53/153 (34%), Positives = 83/153 (54%), Gaps = 3/153 (1%)
 Frame = +2

Query: 259 KDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQV--M 316
           +D WEIP ES+     LG G  G V++G       VA+K ++         ++E  +  +
Sbjct: 281 QDDWEIPFESITDLEWLGSGAQGAVFLGKLCAE-EVAVKKVRD--------IKETDIRNL 433

Query: 317 KKLRHEKLVQLYAVVSEEPIY-IVTEYMNKGSLLDFLKGETGKYLRLPQLVDMSAQIASG 375
           +KL H  ++    V ++ P Y I+ EY   G L + L+   GK +    ++D S QIASG
Sbjct: 434 RKLNHPNIISFKGVCTQAPCYCIIMEYCPYGQLYEVLR--DGKEIPPALVLDWSKQIASG 607

Query: 376 MAYVERMNYVHRDLRAANILVGENLVCKVADFG 408
           M Y+     +HRDL++ N+LV +N V K++DFG
Sbjct: 608 MNYLHSHKIIHRDLKSPNVLVAKNDVVKISDFG 706
>00715
          Length = 1788

 Score = 83.6 bits (205), Expect = 2e-16,   Method: Compositional matrix adjust.
 Identities = 71/256 (27%), Positives = 114/256 (44%), Gaps = 39/256 (15%)
 Frame = +1

Query: 294 VAIKTLKPGTMSPEAFLQE-----AQVMKKLRHEKLVQLYAVVS----EEPIYIVTEY-- 342
           VA+K     + +P A  Q            LRH  +V +    S    E+  ++  EY  
Sbjct: 7   VAVKIYHKRSSNPRALRQSYSNELLAFRCGLRHVNVVSILGATSLHRFEDGAWLAMEYVG 186

Query: 343 -MNKGSLLDFLKGETGKYLRLPQLVDMSAQIASGMAYVERMNYVHRDLRAANILVGENLV 401
            +N  ++L+  + +    +RL     ++ Q+A G+ Y+  +N VH DL+ AN L+  +L 
Sbjct: 187 PLNLQTILNDHQQDIDSSMRL----SLALQMARGLHYLHSINIVHLDLKPANCLLTRDLK 354

Query: 402 CKVADFGLARLI----------------EDNEYTARQGA-----KFPIKWTAPEAALYGR 440
            ++ADFG    +                 + E T  QGA        + + APE     +
Sbjct: 355 LRIADFGCCHQLTPTGLDMGEREGGMAGNELELTPVQGAWKNELAGTLAYRAPELLKGLQ 534

Query: 441 FTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPECPES------LH 494
            +++SDV+S GI L ++ T+ + PY G+    V+ QV      PCPP   E         
Sbjct: 535 PSVRSDVYSLGITLWQMCTR-QGPYEGVPAHAVVYQVVSKDLRPCPPPSTEDDPFEVMFR 711

Query: 495 DLMCQCWRKEPEERPT 510
           DL  QCW +  E+RPT
Sbjct: 712 DLYTQCWARRVEDRPT 759
>22005
          Length = 873

 Score = 83.6 bits (205), Expect = 2e-16,   Method: Compositional matrix adjust.
 Identities = 59/193 (30%), Positives = 93/193 (48%), Gaps = 44/193 (22%)
 Frame = +1

Query: 309 FLQEAQVMKKLRHEKLVQLYAVVS-EEPIYIVTEYMNKGSLLDFLKGETGKYLRLP---- 363
           F +EA +M    H  +V+L  V +  +P+ ++ E+M+KG L DFL+  + +   LP    
Sbjct: 151 FEREASLMADFDHPNIVKLLGVCAIGKPMCLLFEFMSKGDLNDFLRLCSPENYNLPVSRS 330

Query: 364 --QLVDM------------------------------------SAQIASGMAYVERMNYV 385
              +VD+                                    S QI++GMAY+ + +YV
Sbjct: 331 QNLVVDLEDGLRVEVEAEECEKDTQSEDRDCSGMLXTKDQLYISQQISAGMAYLAQKDYV 510

Query: 386 HRDLRAANILVGENLVCKVADFGLARLIED-NEYTARQGAKFPIKWTAPEAALYGRFTIK 444
           HRDL A   +        ++DFGLAR +   + Y   +    PI+W   EA LY +F+ +
Sbjct: 511 HRDL-ATRTVXSRTT*S*ISDFGLARSVHSVDYYRGSEQDAIPIRWMPLEAILYSKFSTQ 687

Query: 445 SDVWSFGILLTEL 457
           SDVWSFG++L E+
Sbjct: 688 SDVWSFGVVLWEI 726
>13305
          Length = 549

 Score = 77.0 bits (188), Expect = 2e-14,   Method: Compositional matrix adjust.
 Identities = 36/102 (35%), Positives = 57/102 (55%), Gaps = 4/102 (3%)
 Frame = +2

Query: 423 GAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYR 482
             + PI+W A E+     +T +SDVWSFG++L E+ T G  PY     +++   ++ GYR
Sbjct: 2   STRVPIRWMAVESLFNNTYTTQSDVWSFGVVLWEIFTLGGTPYSSTDTQQLFAFLKDGYR 181

Query: 483 MPCPPECPESLHDLMCQCWRKEPEERPTFE----YLQAFLED 520
           +  P  C ++ + +M QCW +  + RPTF      LQ  L+D
Sbjct: 182 LKRPKLCDQNTYAMMLQCWNENAQRRPTFPELCGRLQRMLDD 307
>17253
          Length = 483

 Score = 76.3 bits (186), Expect = 3e-14,   Method: Composition-based stats.
 Identities = 50/153 (32%), Positives = 71/153 (46%), Gaps = 16/153 (10%)
 Frame = -1

Query: 294 VAIKTLKPGTMSPEA--FLQEAQVMKKL-RHEKLVQLYAVVS-EEPIYIVTEYMNKGSLL 349
           VA+KT        E   FL+E  +M+KL RH  +V      +  +P  I+ E+   G LL
Sbjct: 459 VAVKTHNEAATDAEKSEFLRELSIMRKLPRHPNVVSFMGCCTMSDPALILMEFCCHGDLL 280

Query: 350 DFLKGE----------TGKYLRLPQLVDMSAQIASGMAYVERMNYVHRDLRAANILVGEN 399
            FL+            T   L        +  +A GMA+V     VHRD+ A N+L+ E 
Sbjct: 279 SFLRKRRPDRTVFLTSTANDLTARDFFSFALHVARGMAHVANNKIVHRDVAARNVLISER 100

Query: 400 LVCKVADFGLARLIEDNE--YTARQGAKFPIKW 430
            VCKV+DFGL+R + D    Y        P++W
Sbjct: 99  NVCKVSDFGLSRRVGDQNDVYEIVSRRPLPLRW 1
>07833
          Length = 1504

 Score = 75.1 bits (183), Expect = 6e-14,   Method: Compositional matrix adjust.
 Identities = 61/224 (27%), Positives = 112/224 (50%), Gaps = 13/224 (5%)
 Frame = -3

Query: 309  FLQEAQVMKKLRHEKLVQLYAVVSEEP-IYIVTEYMNKGSLLDFLKGETGKYLRLPQLVD 367
            F++E   ++   H  ++ + A  ++ P + +++++M  GSL + L GE+G  +   Q + 
Sbjct: 1478 FMEEFPRLRIFNHPNVLPVLACCNQPPNLVLISQFMPFGSLYNTLHGESGIVVDQNQSLR 1299

Query: 368  MSAQIASGMAYVERM-----NYVHRDLRAANILVGENLVCKV--ADFGLARLIEDNEYTA 420
             +  IA GM ++  M     N++   L + ++++ E+L  ++  AD+  +          
Sbjct: 1298 FAMDIARGMEFLHSMEPTIPNFL---LTSKHVMIDEDLTARINMADYCFS--------FH 1152

Query: 421  RQGAKFPIKWTAPEAALYGR----FTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQ 476
             +G  +   W APEA L  R     T  +D+WSF IL+ EL T+  VP+  + + EV  +
Sbjct: 1151 EKGKVYSPAWMAPEA-LQRRPDDINTRAADMWSFAILMWELETR-EVPFAELSSMEVGMK 978

Query: 477  VE-RGYRMPCPPECPESLHDLMCQCWRKEPEERPTFEYLQAFLE 519
            V   G R+  PP     +  L+  C  +EP +RP F+ +   LE
Sbjct: 977  VALEGLRISIPPGISLHMSRLIKICMNEEPGKRPRFDMIIPILE 846
>12721
          Length = 821

 Score = 73.9 bits (180), Expect = 1e-13,   Method: Compositional matrix adjust.
 Identities = 60/252 (23%), Positives = 110/252 (43%), Gaps = 13/252 (5%)
 Frame = +1

Query: 248 PTSKPQTQGLAKDAWEI----------PRESLRLEVKLGQGCFGEVWMGTWNGTTRVAIK 297
           P+  P+ Q L+ + +            PR  L   +K+G+G  G V + T     ++A+K
Sbjct: 1   PSPMPEPQRLSHEQFRAALQMVVTPGDPRTFLDDFMKIGEGSTGIVCIATSRDGRQMAVK 180

Query: 298 TLK-PGTMSPEAFLQEAQVMKKLRHEKLVQLYA--VVSEEPIYIVTEYMNKGSLLDFLKG 354
            +        E    E  VM+   H  +V++Y   +V++E +++V E+M  G+L D +  
Sbjct: 181 KMDLRKQQRRELLFNEVVVMRDYHHPNIVEMYNSYLVNDE-LWVVMEFMEGGALTDIV-- 351

Query: 355 ETGKYLRLPQLVDMSAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIE 414
            T   +   Q+  +       +A++     +HRD+++ +IL+  +   K+ DFG    + 
Sbjct: 352 -TNNRMDEVQIATVCRACLKALAFLHANGVIHRDIKSDSILLSHDGKVKLXDFGFCAQVT 528

Query: 415 DNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVL 474
            +    +     P  W APE      +  + D+WS GI++ E+        P   N   L
Sbjct: 529 QDLQKRKSLVGTPY-WMAPEVISRLPYGPEVDIWSLGIMVMEMIDAE----PPFFNEPPL 693

Query: 475 DQVERGYRMPCP 486
             + R   MP P
Sbjct: 694 QAMRRIRDMPPP 729
>18921
          Length = 697

 Score = 71.6 bits (174), Expect = 8e-13,   Method: Compositional matrix adjust.
 Identities = 53/195 (27%), Positives = 91/195 (46%), Gaps = 2/195 (1%)
 Frame = +2

Query: 265 PRESLRLEVKLGQGCFGEVWMGTWNGTTRV-AIKTLKPGTMSPEAFLQEAQVMKKLRHEK 323
           P +   +  KLG+G +G V+      T +V AIK + P     +  ++E  +M++   + 
Sbjct: 23  PEDVFDILGKLGEGSYGSVFKSLHKETGQVLAIKQV-PVDTDLQEIIKEISIMQQCDSKY 199

Query: 324 LVQLY-AVVSEEPIYIVTEYMNKGSLLDFLKGETGKYLRLPQLVDMSAQIASGMAYVERM 382
           +V+ Y +      ++IV EY   GS+ D ++    K L   ++  +      G+ Y+   
Sbjct: 200 IVKYYGSYFKNTDLWIVMEYCGAGSVSDIMRLRN-KTLVEREIATILYYTLKGLXYLHSR 376

Query: 383 NYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFT 442
             +HRD++A NIL+      K+ADFG+A  + D           P  W APE      + 
Sbjct: 377 RKIHRDIKAGNILLNNEGHAKLADFGVAGQLTDTMAKRNTVIGTPY-WMAPEVIQEIGYD 553

Query: 443 IKSDVWSFGILLTEL 457
             +D+WS GI   E+
Sbjct: 554 CVADIWSLGITALEM 598
>01060
          Length = 1800

 Score = 70.1 bits (170), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 62/250 (24%), Positives = 113/250 (45%), Gaps = 6/250 (2%)
 Frame = +1

Query: 244 TTVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTR-VAIKTLK-- 300
           T  C   K   + L  D +E     L    K+G+G +G V+      T R +A+K ++  
Sbjct: 7   TLTCLLLKLNIKRLMMD-FETALSDLTDFQKIGEGTYGVVYKCRHRATGRKLAMKKIRLR 183

Query: 301 -PGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSE-EPIYIVTEYMNKGSLLDFLKGETGK 358
                 P + ++E  ++++LRH  +V L  V+ E E +++V E+++    +   K   G 
Sbjct: 184 GSEDGVPSSAIREIAMLRELRHTNIVCLEDVIMEDERLFLVFEFLSMDLKMYIDKFPEGV 363

Query: 359 YLRLPQLVDMSAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEY 418
            L    +     QI +G+ +  +   VHRDL+  N+L+      K+ADFG+AR       
Sbjct: 364 VLDRRLVKSYVFQIVTGIXFCHQRRIVHRDLKPQNLLINHTGAIKIADFGMARTFA-LPV 540

Query: 419 TARQGAKFPIKWTAPEAAL-YGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQV 477
            A       + + APE  +   +++   DVWS G +  ++  +     P       +DQ+
Sbjct: 541 RAYTHEVVTLWYRAPEILMGASKYSTPVDVWSIGTIFADMLIRT----PIFKGDSEIDQL 708

Query: 478 ERGYRMPCPP 487
            + +R+   P
Sbjct: 709 FKIFRIIGTP 738
>00300
          Length = 2318

 Score = 70.1 bits (170), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 60/234 (25%), Positives = 116/234 (49%), Gaps = 14/234 (5%)
 Frame = -1

Query: 274  KLGQGCFGEVWMGTWNGTTRV-AIKTLK--PGTMSP-EAFLQEAQVMKKLRHEKLVQLYA 329
            K+G+G FG+V+      T  + A+K +K  P  +        E ++ + ++HE LV+ Y 
Sbjct: 1637 KIGEGQFGKVYTAVNMSTGELMALKEMKFQPNDLQQLREMCDEIKIFEGIQHENLVKYYG 1458

Query: 330  V-VSEEPIYIVTEYMNKGSLLDFLKGETGKYLRLPQLVDMSAQIASGMAYVERMNYVHRD 388
            V V ++ + +  EY + G++ +  K    +YL    +   + +I   + ++   + VHRD
Sbjct: 1457 VEVHKDEMLMFMEYCDTGTIEEAAKMGLPEYL----IRRYTREIVLAVNHLHENSIVHRD 1290

Query: 389  LRAANILVGENLVCKVADFGLARLIEDN-----EYTARQGAK---FPIKWTAPEAALYGR 440
            ++ ANI +  N   K+ DFG +  ++ +     E+    G      P  +T  +   YGR
Sbjct: 1289 IKGANIFLTSNGHVKLGDFGCSVKLKSHTTMPGEFHNLVGTTAYMAPEVFTQNDQGGYGR 1110

Query: 441  FTIKSDVWSFGILLTELTTKGRVPYPGMVNR-EVLDQVERGYRMPCPPECPESL 493
                +D+WS G ++ E+ T G+ P+  + N  +++ +V  G++    P  P+SL
Sbjct: 1109 ---AADIWSLGCVVIEMAT-GKRPWHDLDNNYQIMYKVGIGHK----PAVPDSL 972
>29581
          Length = 1278

 Score = 69.3 bits (168), Expect = 4e-12,   Method: Compositional matrix adjust.
 Identities = 59/191 (30%), Positives = 91/191 (47%), Gaps = 11/191 (5%)
 Frame = -2

Query: 299  LKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVV---SEEPIYIVTEYMNK--GSLLDFLK 353
            L+   +SP      +  +  LRH+ +VQL  VV   S + +++V EY  +   SLLD + 
Sbjct: 1244 LERDMVSPSVVCVRSTFLLNLRHQNIVQLQEVVVGKSLDSLFLVMEYCEQDLASLLDNMP 1065

Query: 354  GETGKYLRLPQLVDMSAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLI 413
                +     Q+  +  Q+  G+ Y+     +HRDL+ +N+L+ +    K+ADFGLAR  
Sbjct: 1064 APFSE----SQVKCIVLQLLKGLRYLHEAFIIHRDLKVSNLLMTDKGCVKIADFGLAR-- 903

Query: 414  EDNEYTARQGAKFP----IKWTAPEAALYGRFTIKS--DVWSFGILLTELTTKGRVPYPG 467
                Y   Q    P    + + APE  L+G  T  +  D+WS G +L EL        P 
Sbjct: 902  ---NYGKPQKPMTPKVVTLWYRAPE-LLFGSKTHSTAIDMWSAGCILGELLGHK----PL 747

Query: 468  MVNREVLDQVE 478
            M  R  L Q+E
Sbjct: 746  MPGRSDLQQIE 714
>01707
          Length = 757

 Score = 65.9 bits (159), Expect = 4e-11,   Method: Compositional matrix adjust.
 Identities = 60/214 (28%), Positives = 108/214 (50%), Gaps = 9/214 (4%)
 Frame = +1

Query: 274 KLGQGCFGEVWMGTWNGTTR-VAIKTLKPGTMSP---EAFLQEAQVMKKLRHEKLVQLYA 329
           K+G+G +G V+      T++ VAIK        P   +  ++E +++K+L+H  LV+L  
Sbjct: 85  KIGEGSYGVVFKCRNKETSQLVAIKKFVESEDDPLIKKIAMREIRMLKQLKHPNLVRLIE 264

Query: 330 VVSEEP-IYIVTEYMNKGSLLDFLKGETGKYLRLPQLVDMSAQIASGMAYVERMNYVHRD 388
           V   +  +++V +Y++   L +  +   G  L  P +  +  Q    + +  + N +HRD
Sbjct: 265 VFRRKKRLHLVFDYVDHTLLNELDRYPRG--LPEPMVKRIIYQTLLAVNFCHQYNTIHRD 438

Query: 389 LRAANILVGENLVCKVADFGLARLIE--DNEYTARQGAKFPIKWTAPEAALYG--RFTIK 444
           ++  NIL+      K+ DFG AR++    +EYT     ++   + APE  L G  ++   
Sbjct: 439 VKPENILITRQGQVKLCDFGFARILTGPGDEYTDYVATRW---YRAPE-LLVGDTQYGPP 606

Query: 445 SDVWSFGILLTELTTKGRVPYPGMVNREVLDQVE 478
            DVW+ G +  EL T G+  +PG   R  +DQ+ 
Sbjct: 607 VDVWAIGCVFAELLT-GQALWPG---RSDVDQLH 696
>04591
          Length = 1117

 Score = 65.1 bits (157), Expect = 8e-11,   Method: Compositional matrix adjust.
 Identities = 45/167 (26%), Positives = 82/167 (49%), Gaps = 12/167 (7%)
 Frame = -2

Query: 306  PEAFLQEAQVMKKLRHEKLVQLYAVVSEEP---------IYIVTEYMNKGSLLDFLKGET 356
            P   L+E +++++L HE +VQL  +   +           Y++ EY +   L   L    
Sbjct: 1089 PITALREIKILQQLEHENVVQLQEICHTQAGPYNRYKSTFYLIFEYCDY-DLAGLLNNLR 913

Query: 357  GKYLRLPQLVDMSAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLAR-LIED 415
             K+  L    ++ +Q+ +G+ Y+     +HRD++AANIL+  + V K+ADFGL+R  ++ 
Sbjct: 912  VKF-SLADKKNLMSQLLNGLFYIHTKQILHRDIKAANILLTRDGVLKLADFGLSRPWVKS 736

Query: 416  NEYTARQGAKFPIKWTAPEAALYG--RFTIKSDVWSFGILLTELTTK 460
               T R        W  P   L G   +  + D+W  G ++ E+ ++
Sbjct: 735  KRLTNR----VVTLWYRPPELLLGEREYGPEIDMWGVGCIMAEMWSR 607
>27546
          Length = 426

 Score = 64.3 bits (155), Expect = 1e-10,   Method: Composition-based stats.
 Identities = 35/108 (32%), Positives = 60/108 (55%), Gaps = 1/108 (0%)
 Frame = -1

Query: 309 FLQEAQVMKKLRHEKLVQLYAVVSEEP-IYIVTEYMNKGSLLDFLKGETGKYLRLPQLVD 367
           F +E +++ +L H  ++Q+++++   P I+I   Y  KG +L  +K +TG  +   Q   
Sbjct: 339 FPRELEILTRLDHPNIIQIHSILQRGPKIFIFMRYAEKGDMLSHIK-KTGP-IDEAQTKV 166

Query: 368 MSAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIED 415
              Q+A  + Y+   +  HRDL+  NIL+ + L  K+ADFG AR   D
Sbjct: 165 WFFQMAKALQYLHSHDIAHRDLKCENILLSKRLNVKIADFGFARYCRD 22
>14126
          Length = 1265

 Score = 63.9 bits (154), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 53/237 (22%), Positives = 107/237 (45%), Gaps = 18/237 (7%)
 Frame = +3

Query: 275 LGQGCFGEVW-------MGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLR---HEKL 324
           +G G +G V+        G +    R+ +   + G   P   ++E  ++K+L    H  +
Sbjct: 213 IGNGAYGTVYKARDLRNQGEFVAMKRIRLNNTEEGM--PMMAIREISMLKQLEQYEHPNV 386

Query: 325 VQLYAVVSEEPIYIVTEYMNKGSLLDFLKGETGKYL-RLP-------QLVDMSAQIASGM 376
           V+L  V       I    +    + ++++ +   YL + P       ++ D+  Q+ +G+
Sbjct: 387 VRLLDVSHNT---ITDREIRLNLVFEYIEHDLATYLAKCPSPGLGPDRIKDLMLQLLNGV 557

Query: 377 AYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAA 436
            ++     VHRDL+  N+L+ ++   K+ADFGLAR+   + + A       + + +PE  
Sbjct: 558 DFLHSNRIVHRDLKPQNLLISKDGRLKLADFGLARIY--SFHMALTTVVVTLWYRSPEVL 731

Query: 437 LYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPECPESL 493
           +   +    D+WS G +  EL T+ R  + G    + L ++     +P   + PE +
Sbjct: 732 MQAEYGTSVDIWSCGCIFAELFTR-RALFKGSSEFDQLKKIFEVIGLPPAGDWPEGV 899
>14420
          Length = 528

 Score = 62.0 bits (149), Expect = 5e-10,   Method: Compositional matrix adjust.
 Identities = 40/162 (24%), Positives = 80/162 (49%), Gaps = 3/162 (1%)
 Frame = +2

Query: 307 EAFLQEAQVMKKLRHEKLVQ-LYAVVSEEPIYIVTEYMNKGSLLDFLKGETGKYLRLPQL 365
           E  + E  VM++ ++  +V  L + +  E +++V E++  GSL D +   T   +   Q+
Sbjct: 35  ELIINEILVMRENQNPNIVNYLDSYLVGEELWVVMEFLAGGSLTDVV---TETCMDEGQI 205

Query: 366 VDMSAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLI--EDNEYTARQG 423
             +  +    + ++     +HRD+++ NIL+G +   K+ DFG    +  E ++ +   G
Sbjct: 206 AAVCRECLQALEFLHENQVIHRDIKSDNILLGMDGSVKLTDFGFCAQLSPEQSKRSTMVG 385

Query: 424 AKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPY 465
             +   W APE     ++    D+WS G++  E+  +G  PY
Sbjct: 386 TPY---WMAPEVVTRKQYGPTVDIWSLGVMCIEM-IEGEPPY 499
>31885
          Length = 529

 Score = 60.5 bits (145), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 48/156 (30%), Positives = 71/156 (45%), Gaps = 6/156 (3%)
 Frame = -2

Query: 313 AQVMKKLRHEKLVQL-YAVVSEEPIYIVTEYMNKGSLLDFLKGETGKYLRLPQLVDMSAQ 371
             ++ +L H  LV L YA   EE +++V +    G L   ++ E     R   +     Q
Sbjct: 519 VDMLTRLDHPFLVNLWYAFQDEEDLFMVVDLFLGGDLRYHMQQEVS--FREDCVKFYLCQ 346

Query: 372 IASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKWT 431
           +A  + Y+     VHRD++  NIL+ E   C V DF +A  +ED+E         P  + 
Sbjct: 345 LALVLDYLRSQKIVHRDIKPDNILLDEQGHCHVTDFNIATQLEDDELATSTSGTRP--YM 172

Query: 432 APE---AALYGR--FTIKSDVWSFGILLTELTTKGR 462
           APE    A+  R  +    D WS G+ L EL  K R
Sbjct: 171 APEVYGVAINERRGYGFPVDWWSLGVSLFELLKKRR 64
>01966
          Length = 1735

 Score = 58.9 bits (141), Expect = 5e-09,   Method: Compositional matrix adjust.
 Identities = 32/107 (29%), Positives = 58/107 (54%), Gaps = 1/107 (0%)
 Frame = -1

Query: 306  PEAFLQEAQVMKKLRHEKLVQLYAVVSE-EPIYIVTEYMNKGSLLDFLKGETGKYLRLPQ 364
            P + ++E  ++++LRH  +V L  V+ E E +++V E+++    +   K   G  L    
Sbjct: 1582 PSSAIREIAMLRELRHTNIVCLEDVIMEDERLFLVFEFLSMDLKMYIDKFPEGVVLDRRL 1403

Query: 365  LVDMSAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLAR 411
            +     QI +G+ +  +   VHRDL+  N+L+      K+ADFG+AR
Sbjct: 1402 VKSYVFQIVTGINFCHQRRIVHRDLKPQNLLINHTGAIKIADFGMAR 1262
>03240
          Length = 1683

 Score = 58.5 bits (140), Expect = 7e-09,   Method: Compositional matrix adjust.
 Identities = 47/158 (29%), Positives = 79/158 (50%), Gaps = 9/158 (5%)
 Frame = -3

Query: 275  LGQGCFGEVWMGTWNGTTRV-AIKTLKPGTM---SPEAFLQ-EAQVMKKLRHEKLVQLYA 329
            LG G FGEV +   N T  + A+KTL+   +   +  A ++ E  ++ +  +E +V+LY 
Sbjct: 1267 LGVGAFGEVSLCRKNDTGMLYAMKTLRKSDVLKRNQVAHVKAERDILAEADNEWVVKLYY 1088

Query: 330  VVSEEP-IYIVTEYMNKGSLLDFLKGETGKYLRLPQLVDMSAQIASGMAYVERMNYVHRD 388
               +   +Y V +Y+  G L+  L     + L  P      A++   +  V RM ++HRD
Sbjct: 1087 SFQDHNYLYFVMDYVPGGDLMGLLI--RMEILDEPLARFYVAELVQAIESVHRMGFIHRD 914

Query: 389  LRAANILVGENLVCKVADFGLA---RLIEDNEYTARQG 423
            ++  NIL+  N   K+ DFGL    R   +++Y  R G
Sbjct: 913  IKPDNILIDRNGHIKLTDFGLCTGFRWTHNSKYYQRDG 800
>09606
          Length = 1300

 Score = 58.5 bits (140), Expect = 7e-09,   Method: Compositional matrix adjust.
 Identities = 70/303 (23%), Positives = 130/303 (42%), Gaps = 34/303 (11%)
 Frame = -3

Query: 267  ESLRLEVKLGQGCFGEVWMGTWNGTTR-VAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLV 325
            E+  L  +LG+G    ++ G   GT   VAI  ++     PE      ++   + H  +V
Sbjct: 1115 ENFVLYEELGKGEHSIIYKGRRKGTINFVAIHCIEK-CKRPEV-TNTVRMTHDISHPNVV 942

Query: 326  QLYA-VVSEEPIYIVTEYMNKGSLLDFLKGETGKYLRLPQLVDMSAQIASGMAYVERMNY 384
            Q +    +   +++V E    GSL D L  +   +L    + D    + +G+ Y+  +  
Sbjct: 941  QFHEWYETSNHLWLVVELCTGGSLADILAQD--HHLPETSIRDFGIHLVTGLHYIHSLGI 768

Query: 385  VHRDLRAANILVGENLVCKVADFGLARLIEDNEYT-----ARQGAKFPIK---------- 429
            +  DLR + +L+  + V K ADFGL+++  +N        A  G ++ I+          
Sbjct: 767  LFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEAGDQWNIQSAEEMMKQVP 588

Query: 430  ------WTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPG---------MVNREVL 474
                  + APE       +I SD+W+ G +  E+ + G  P+ G         ++N+E  
Sbjct: 587  TSGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFS-GHPPFLGETYDITKDKVLNKEFP 411

Query: 475  DQVERGYRMPCPPECPESLHDLMCQCWRKEPEERPTFEYL--QAFLEDYFTSTEPQYQPG 532
                +G R+   P  PE L +L+    +K+   R ++  L   AF +   +S   ++   
Sbjct: 410  LPKVKGSRLSAKPS-PEFL-NLLESLLQKDSTRRLSWASLVKHAFWQGGLSSLVKEFTMS 237

Query: 533  ENL 535
            E +
Sbjct: 236  EEI 228
>13066
          Length = 551

 Score = 58.2 bits (139), Expect = 8e-09,   Method: Compositional matrix adjust.
 Identities = 43/179 (24%), Positives = 81/179 (45%), Gaps = 4/179 (2%)
 Frame = +3

Query: 277 QGCFGEVWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEPI 336
            G F + +        ++  K   P     + F +E  ++ KL H  ++Q+++++   P 
Sbjct: 21  HGTFNDGYGRNIKLACKIIDKEKAPVDFVEKFFPRELDLLTKLDHPYIIQIHSILQRXPK 200

Query: 337 -YIVTEYMNKGSLLDFLKGETGKYLRLPQLVDMSAQIASGMAYVERMNYVHRDLRAANIL 395
            +I   +  +G LL +++ E G +++  Q      Q+ + + Y+   +  HRDL+  NIL
Sbjct: 201 NFIFMRFAERGDLLTYIQ-EVG-FVKEKQAKIWFYQMTTALNYLHSYDVAHRDLKCENIL 374

Query: 396 VGENLVCKVADFGL--ARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIK-SDVWSFG 451
           +  +   K+ADFG   A + E  E    +       + APE      +  K +D WS G
Sbjct: 375 LSSHFNVKLADFGFACACITESGEKYMSRTYCGSAAYAAPEIVYGAPYAPKVADAWSLG 551
>18484
          Length = 635

 Score = 58.2 bits (139), Expect = 9e-09,   Method: Compositional matrix adjust.
 Identities = 31/109 (28%), Positives = 57/109 (52%)
 Frame = +1

Query: 369 SAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPI 428
           +A+IA G+ ++     ++RDL+  N+++      K+ADFG+ +     + T R     P 
Sbjct: 61  AAEIAVGLFFLHDQGIIYRDLKLDNVMLDSEGHIKIADFGMCKEGMTGDATTRTFCGTP- 237

Query: 429 KWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQV 477
            + APE  LY  ++   D W++G+LL E+   G+ P+ G    E+   +
Sbjct: 238 DYIAPEIVLYQPYSKSVDWWAYGVLLFEMLA-GQPPFDGEDEDELFSSI 381
>07836
          Length = 1478

 Score = 57.8 bits (138), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 62/239 (25%), Positives = 107/239 (44%), Gaps = 47/239 (19%)
 Frame = -1

Query: 319  LRHEKLVQLYAVV-----SEEPIYIVTEYMNKGSLLDFLKGETGKYLRLPQLVDMSAQIA 373
            LRHE ++   A       S   ++++T+Y   GSL D+L     + L   +++ ++    
Sbjct: 1394 LRHENILGFIAADIKGTGSWTQLFLITDYHENGSLHDYL---LSRVLDSSEMLALAHSAI 1224

Query: 374  SGMAYVE--------RMNYVHRDLRAANILVGENLVCKVADFGLA-RLI-EDNEYTA--- 420
             G+A++         +    HRD+++ NILV +N  C +AD GLA R I E NE      
Sbjct: 1223 CGLAHLHIEIFGTRGKPAIAHRDIKSKNILVKKNGTCCIADLGLAVRYISESNEVDVAPN 1044

Query: 421  -RQGAKFPIKWTAPEAALYGRFTIK-------SDVWSFGILLTEL---------TTKGRV 463
             RQG K   ++ APE  L     +K       +D+++FG+++ E+           + +V
Sbjct: 1043 PRQGTK---RYMAPE-VLEMLLNVKNFDAFKQADMYAFGLVMWEIARCCVIGGVAEEYQV 876

Query: 464  PY-------PGMVNREVLDQVERGYRMPCPPECPES-----LHDLMCQCWRKEPEERPT 510
            P+       P   +  ++  V++  R   P    E      +  +MC+CW   P  R T
Sbjct: 875  PFYNCLPHDPSFEDVRLVVSVDK-VRPDIPLRWQEDPIMKVMVKVMCECWSGNPAARLT 702
>13212
          Length = 1067

 Score = 57.0 bits (136), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 44/172 (25%), Positives = 80/172 (46%), Gaps = 10/172 (5%)
 Frame = -1

Query: 349  LDFLKGETGKYLRLPQLVDMSAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFG 408
            LD +  +  K +   Q+  +  ++   + ++ R + +HRD++A N+L+  +   K+ADFG
Sbjct: 1022 LDSIMVDLEKPMTEAQICYVCHEMCMALDFLHRHHVIHRDIKAGNVLLTIDGEVKLADFG 843

Query: 409  LARLIEDNEYTARQGAKF---PIKWTAPEAALYGR-----FTIKSDVWSFGILLTELTTK 460
            ++     N  T ++   F   P  W APE  L        +  K+D+WS G+ L E   +
Sbjct: 842  VSA---KNTQTQQKRDTFIGTPY-WMAPEVVLCETLKDTPYDFKADIWSLGVTLIEF-AQ 678

Query: 461  GRVPYPGMVNREVLDQVERGY--RMPCPPECPESLHDLMCQCWRKEPEERPT 510
               P   M    VL ++ +     +  P +  +   D + +C  K+P  RPT
Sbjct: 677  IEPPNKEMHPMRVLIKIHKSDPPTLEKPKKWTKLFKDFIAKCLVKDPNLRPT 522
>25550
          Length = 941

 Score = 56.2 bits (134), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 27/63 (42%), Positives = 39/63 (61%)
 Frame = +3

Query: 463 VPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYF 522
           V YPG+   EV   +ERGYRM  P   P  ++ LM +CW+ +P+ERPTF+ +   LE+ F
Sbjct: 36  VXYPGVDLTEVYHLLERGYRMERPQGTPADVYILMLKCWQWDPKERPTFKEIHYLLENMF 215

Query: 523 TST 525
             +
Sbjct: 216 EKS 224
>12672
          Length = 773

 Score = 56.2 bits (134), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 44/165 (26%), Positives = 74/165 (44%), Gaps = 17/165 (10%)
 Frame = +3

Query: 373 ASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPI---K 429
           ASG+ Y+    +VHRD++ ANIL+      KV DF         E    Q A   I    
Sbjct: 21  ASGIQYLNDNGHVHRDIKTANILLDSEYTAKVGDFATVVSAPSGEGKTVQNASVVIGTAA 200

Query: 430 WTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYP-----GMVNREVLDQVERGYRM- 483
           + APE A++   + K D +SFG++L E+ T G V          ++  +++ VE    + 
Sbjct: 201 YLAPE-AIHFDVSTKLDSYSFGVVLLEVIT-GLVAQDYSREERTLSSHIMENVEEPEEIH 374

Query: 484 --------PCPPECPESLHDLMCQCWRKEPEERPTFEYLQAFLED 520
                     P    + L+D+  +C     ++RP  + ++  LE+
Sbjct: 375 DFVDQSAGTWPDGAVDKLYDISMRCLNLSKKQRPNVKDIRPELEE 509
>28157
          Length = 400

 Score = 55.1 bits (131), Expect = 6e-08,   Method: Composition-based stats.
 Identities = 40/128 (31%), Positives = 63/128 (49%), Gaps = 11/128 (8%)
 Frame = +3

Query: 294 VAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVTEYMNKGSLLDFLK 353
           VA+K ++      ++F+QE + + ++ H  +V LY    + P+ +V EY   GSL + L 
Sbjct: 9   VAVKRIE-SEQEKKSFMQELKQLSRVSHPNIVCLYGACRDHPVCLVMEYAEGGSLYNVLH 185

Query: 354 GETGKYLRLPQLVDMSA-----QIASGMAYVERMN---YVHRDLRAANILV---GENLVC 402
           G   +    PQ     A     Q A G+ Y+  M     +HRDL+  N+L+   G  L  
Sbjct: 186 GSGPQ----PQYTAAHAMNWLLQCALGVEYLHGMKPKALIHRDLKPPNLLLIQCGTKL-- 347

Query: 403 KVADFGLA 410
           K+ DFG A
Sbjct: 348 KICDFGTA 371
>04138
          Length = 800

 Score = 54.3 bits (129), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 33/92 (35%), Positives = 48/92 (52%), Gaps = 7/92 (7%)
 Frame = +1

Query: 376 MAYVERMNYVHRDLRAANILVGENLVCKVADFGLAR-----LIEDNEYTARQGAKFPIKW 430
           + Y+ R   +HRD++AANIL+ +  V K+ADFGLAR     L + N YT R        W
Sbjct: 52  LYYIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNR----VVTLW 219

Query: 431 TAPEAALYG--RFTIKSDVWSFGILLTELTTK 460
             P   L G   ++   D W  G ++ E+ T+
Sbjct: 220 YRPPELLLGDRNYSTAIDQWGAGCIMAEMWTR 315
>11228
          Length = 2155

 Score = 52.0 bits (123), Expect = 6e-07,   Method: Compositional matrix adjust.
 Identities = 43/152 (28%), Positives = 76/152 (50%), Gaps = 6/152 (3%)
 Frame = -2

Query: 89   VALYDYESRTETD-LSFKKGERLQIVNNTEGDWWLAHSLSTGQTGYIPSNYVAPSDS--- 144
            VA+  Y   T++D LSF KG+   + N  E  W       T ++G +P+ +V   D    
Sbjct: 1662 VAMLSYRKATDSDELSFCKGDVFVVQNEMEDGWLWVTCERTKESGLVPAPFVKDLDGDYE 1483

Query: 145  -IQAEEWYFGKITRRES-ERLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVK 202
             +++  ++   +++ E+ E+L+L  E   G+FLVR+SE   G Y L    F   K  +V+
Sbjct: 1482 PVESLPYFHSCLSKEEAVEKLMLAGE---GSFLVRQSENYPGDYSLF---FLCEK--DVR 1327

Query: 203  HYKIRKLDSGGFYITSRTQFNSLQQLVAYYSK 234
             ++I +   G  ++     F+SL  ++  Y K
Sbjct: 1326 RFRIER--RGNQFLVGGRLFDSLDGVIKRYMK 1237

 Score = 38.1 bits (87), Expect = 0.009,   Method: Compositional matrix adjust.
 Identities = 21/57 (36%), Positives = 33/57 (57%)
 Frame = -1

Query: 133  YIPSNYVAPSDSIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLS 189
            +I S   AP   +    WY G++ R  +E LL + +   G++LVRESE+  G++ LS
Sbjct: 2011 HINSALTAPDQKL----WYHGRLGRAGAEELLRDQDA--GSYLVRESESKLGSFVLS 1859
>19761
          Length = 473

 Score = 51.2 bits (121), Expect = 9e-07,   Method: Compositional matrix adjust.
 Identities = 39/137 (28%), Positives = 63/137 (45%), Gaps = 3/137 (2%)
 Frame = -3

Query: 371 QIASGMAYVERMN--YVHRDLRAANILVGENLVCKVADFGLAR-LIEDNEYTARQGAKFP 427
           Q AS + Y+       +HRDL+  NI V E    ++ D GLAR L    ++   Q     
Sbjct: 399 QTASALNYMHTHTPVILHRDLKPQNIYVTEKGDVRLGDLGLARKLTGPADFATSQVGT-- 226

Query: 428 IKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPP 487
           I + +PE      +  KSD+WS G +  ++T K      G++   +L QV  G ++P P 
Sbjct: 225 IMYLSPEILSQQPYNSKSDIWSLGCVFYDITGKKGSDEMGVMF--LLVQVMGGRKLPLPD 52

Query: 488 ECPESLHDLMCQCWRKE 504
              +   D + +   K+
Sbjct: 51  HYSQEFRDTISRMLTKD 1
>21079
          Length = 878

 Score = 49.7 bits (117), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 41/142 (28%), Positives = 66/142 (46%), Gaps = 9/142 (6%)
 Frame = +1

Query: 321 HEKLVQLY-AVVSEEPIYIVTEYMNKGSLL------DFLKGETGKYLRLPQLVDMSAQIA 373
           H KL+ L+ A  +   + +V E++  G L       DF+  E          V    QI 
Sbjct: 1   HPKLLMLWDAFEAPRTMVLVMEFVGAGELFERVIRDDFVLTER-------DCVHFVRQIC 159

Query: 374 SGMAYVERMNYVHRDLRAANIL-VGENL-VCKVADFGLARLIEDNEYTARQGAKFPIKWT 431
           SG+ Y+   + +H DL+  N+L V +N    K+ DFGLAR  +  +  + Q      ++ 
Sbjct: 160 SGVGYMHTQSILHLDLKPENVLCVSDNSNQIKIIDFGLARFYKPGD--SLQVLFGTPEFI 333

Query: 432 APEAALYGRFTIKSDVWSFGIL 453
           APE   Y      +D+WS G++
Sbjct: 334 APEVVNYDEINFTTDMWSIGVI 399
>14257
          Length = 919

 Score = 49.7 bits (117), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 31/89 (34%), Positives = 47/89 (52%)
 Frame = -3

Query: 148 EEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIR 207
           EEWY GKI R+E+E+LL       G FLVRE+  +   + LS       +  NV+H  + 
Sbjct: 896 EEWYHGKIGRKEAEKLL----ELDGDFLVREASNSAAQFVLS-----GRQNGNVRHLLL- 747

Query: 208 KLDSGGFYITSRTQFNSLQQLVAYYSKHA 236
            +D  G   T    F+S+  L+ Y+ ++A
Sbjct: 746 -VDPDGIVRTKDFIFDSVSHLINYHRQNA 663
>21210
          Length = 518

 Score = 48.9 bits (115), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 33/89 (37%), Positives = 49/89 (55%), Gaps = 5/89 (5%)
 Frame = +3

Query: 433 PEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYR--MPCPPECP 490
           P A+ +G + ++SDVWS GI L EL T GR PY   V+  + DQ+++  R   PC P   
Sbjct: 42  PRASSHG-YDVRSDVWSLGITLMELAT-GRFPYRKWVS--IFDQLQQVVRGVAPCLPHDG 209

Query: 491 ESLHD---LMCQCWRKEPEERPTFEYLQA 516
              HD    + +C  K+ ++RP +  L A
Sbjct: 210 AFSHDFVNFVNKCLTKDEKQRPKYNKLLA 296
>30755
          Length = 1137

 Score = 48.9 bits (115), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 31/98 (31%), Positives = 52/98 (53%), Gaps = 2/98 (2%)
 Frame = +2

Query: 370 AQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEY--TARQGAKFP 427
           A+I S + Y+     ++RDL+  N+L+ ++   KVADFGL +  ED  Y  T +     P
Sbjct: 53  AEIISALGYLHSQGIIYRDLKLENLLLDKDGHIKVADFGLCK--EDITYGRTTKTFCGTP 226

Query: 428 IKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPY 465
            ++ APE      +    D W  G+++ E+   GR+P+
Sbjct: 227 -EYLAPEVLDDNDYGRAVDWWGTGVVMYEMIC-GRLPF 334
>06462
          Length = 1511

 Score = 47.8 bits (112), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 33/107 (30%), Positives = 49/107 (45%), Gaps = 4/107 (3%)
 Frame = +1

Query: 134  IPSNYVAPSDSIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDF 193
            +PS+    +D    E WY GK++RRE+E+LL       G FLVRES      + LS    
Sbjct: 1048 MPSSETGVTDPPLHELWYHGKMSRREAEKLL----GKDGDFLVRESGHNXSQFVLS---- 1203

Query: 194  DNAKGLNVKHY----KIRKLDSGGFYITSRTQFNSLQQLVAYYSKHA 236
                    KH+     +  +D  G   T    F+++  LV+Y+  H 
Sbjct: 1204 -------GKHHGQFIHLLLVDPDGIVRTKDYIFDNISHLVSYHCHHG 1323
>19094
          Length = 898

 Score = 47.0 bits (110), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 27/83 (32%), Positives = 40/83 (48%)
 Frame = +1

Query: 375 GMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPE 434
           G+ Y+     +HRD++A NIL+      K+ADFG+A  + D           P  W APE
Sbjct: 94  GL*YLHSRRKIHRDIKAGNILLNNEGHAKLADFGVAGQLTDTMAKRNTVIGTP-YWMAPE 270

Query: 435 AALYGRFTIKSDVWSFGILLTEL 457
                 +   +D+WS GI   E+
Sbjct: 271 VIQEIGYDCVADIWSLGITALEM 339
>29243
          Length = 1147

 Score = 46.6 bits (109), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 37/127 (29%), Positives = 61/127 (48%), Gaps = 4/127 (3%)
 Frame = +2

Query: 124 HSLSTGQTGYIPSNYVAPSDSIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESET-- 181
           HS+  G       +YV    S+++  WY G + R  +++ L     P GTFL+R +    
Sbjct: 248 HSVRNG------PDYVNEPCSLESYNWYVGIMERPVAQKXLDTC--PDGTFLIRVTNNPL 403

Query: 182 TKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKH--ADGL 239
            +G   LS+  + NA    V+H K+ +   G FY+     F+++Q LV +Y  +  AD  
Sbjct: 404 RRGELSLSIK-YANA----VRHIKVNRNPQGRFYLADGRYFDNIQSLVDHYENNELADSF 568

Query: 240 CHRLTTV 246
               TT+
Sbjct: 569 PDVTTTL 589

 Score = 42.7 bits (99), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 21/58 (36%), Positives = 32/58 (55%), Gaps = 2/58 (3%)
 Frame = +2

Query: 89  VALYDYESRTETDLSFKKGERLQIV--NNTEGDWWLAHSLSTGQTGYIPSNYVAPSDS 144
           VA+YDY + + + LS K  +R+ I+  N  +  WW   +L T + GY P  YV   D+
Sbjct: 641 VAVYDYAATSTSQLSMKLNDRIAILSKNGQDKGWWKGENLRTQKIGYFPLAYVDEEDA 814
>26560
          Length = 398

 Score = 46.2 bits (108), Expect = 3e-05,   Method: Composition-based stats.
 Identities = 31/98 (31%), Positives = 52/98 (53%), Gaps = 1/98 (1%)
 Frame = -1

Query: 369 SAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPI 428
           +A++  G+ ++     V+RDL+ ANIL+ EN   +++D GLA         A  G     
Sbjct: 338 AAEVMLGLEHMHSRFVVYRDLKPANILLDENGHVRISDLGLACDFSKKRPHASVGTH--- 168

Query: 429 KWTAPEAALYGR-FTIKSDVWSFGILLTELTTKGRVPY 465
            + APE  + G+ +   +D +SFG +L +L  KG  P+
Sbjct: 167 GYMAPEVLMKGQSYDSSADWFSFGCMLYKL-LKGHSPF 57
>12324
          Length = 946

 Score = 46.2 bits (108), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 29/91 (31%), Positives = 42/91 (46%), Gaps = 4/91 (4%)
 Frame = +3

Query: 55  PPAAEPKLFGGFNSSDTVTSPQRAGP----LAGGVTTFVALYDYESRTETDLSFKKGERL 110
           PPAA P+           T P   GP     A  +   VA+YDYE+  + +L+F +   +
Sbjct: 603 PPAAPPE------DPYAATGPGFLGPDEYMPATYIEKVVAIYDYEAEKDDELTFSENSVI 764

Query: 111 QIVNNTEGDWWLAHSLSTGQTGYIPSNYVAP 141
            ++   +  WW    +  G TG  PSNYV P
Sbjct: 765 YVIRKNDDGWW--EGVMDGVTGLFPSNYVEP 851
>37602
          Length = 804

 Score = 45.8 bits (107), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 27/77 (35%), Positives = 41/77 (53%)
 Frame = -1

Query: 331 VSEEPIYIVTEYMNKGSLLDFLKGETGKYLRLPQLVDMSAQIASGMAYVERMNYVHRDLR 390
           +  E ++I  EY   GS+ D     TG  L  PQ+  +  +   G+ Y+ R   +HRD++
Sbjct: 309 LRREKLWIAMEYCGGGSMQDIYH-VTGP-LTEPQIAFVCRETLKGLHYLHRRGKMHRDIK 136

Query: 391 AANILVGENLVCKVADF 407
            ANIL+ E    K+ADF
Sbjct: 135 GANILLTEEGDVKLADF 85
>15910
          Length = 1361

 Score = 45.4 bits (106), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 29/87 (33%), Positives = 46/87 (52%), Gaps = 3/87 (3%)
 Frame = +2

Query: 370 AQIASGMAYVERMNYVHRDLRAANIL---VGENLVCKVADFGLARLIEDNEYTARQGAKF 426
           + I  G+ Y+     VHRDL+  N+L   + ++   K+ADFGL+R+IE  E         
Sbjct: 485 SDILHGVQYIHANGVVHRDLKPENLLYECMTDDSKLKLADFGLSRIIEP-EVQMSTVCGT 661

Query: 427 PIKWTAPEAALYGRFTIKSDVWSFGIL 453
           P  + APE     ++T   D+WS G++
Sbjct: 662 P-GYCAPEVLKGDKYTPSVDMWSVGVI 739
>11185
          Length = 473

 Score = 45.1 bits (105), Expect = 7e-05,   Method: Compositional matrix adjust.
 Identities = 31/128 (24%), Positives = 57/128 (44%), Gaps = 24/128 (18%)
 Frame = +1

Query: 367 DMSAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNE-----YTAR 421
           D    + +G+ Y+  +  +  DLR + +L+  + V K ADFGL+++  +N        A 
Sbjct: 13  DFGIHLVTGLHYIHSLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAE 192

Query: 422 QGAKFPIK----------------WTAPEAALYGRFTIKSDVWSFGILLTELTTKGRV-- 463
            G ++ I+                + APE       +I SD+W+ G +  E+ +  R+  
Sbjct: 193 AGDQWNIQSAEEMMKQVPTSGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFSGSRLSA 372

Query: 464 -PYPGMVN 470
            P P  +N
Sbjct: 373 KPSPEFLN 396
>32264
          Length = 287

 Score = 43.5 bits (101), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 19/44 (43%), Positives = 29/44 (65%)
 Frame = +1

Query: 477 VERGYRMPCPPECPESLHDLMCQCWRKEPEERPTFEYLQAFLED 520
           +E GYR+   P+ P+S++ LM +CW   PE+RP F+ L   L+D
Sbjct: 1   IEDGYRLQQNPQTPDSVYKLMLRCWEYVPEKRPHFKELYTSLKD 132
>16708
          Length = 1397

 Score = 41.2 bits (95), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 37/149 (24%), Positives = 72/149 (48%), Gaps = 11/149 (7%)
 Frame = -1

Query: 275  LGQGCFGEVWMGTWNGT-TRVAIKTLKPGTMSPEAFLQEAQVMKKLRHE-KLVQLY-AVV 331
            LG+G FG+V+      T  + A+KT    ++     L E + + ++     L Q++ A V
Sbjct: 1379 LGKGVFGKVYEARLLSTHEKAALKT----SILCHHSLDEVEALGRIEGGFYLAQMFGAWV 1212

Query: 332  SEEP---IYIVTEYMNKGSLLDFLKGETGKYLRL----PQLVD-MSAQIASGMAYVERMN 383
            +  P   + I+  +   G L +       K + +    P +V  ++ Q    + ++  + 
Sbjct: 1211 TCLPFPKMNILLHFYEMGPLCNVYAHYKNKEMPIRWSNPAMVCCIAGQXVCALEHIHELG 1032

Query: 384  YVHRDLRAANILVGENLVCKVADFGLARL 412
             VH D++A N+LV  +  CK+ D+G+A+L
Sbjct: 1031 VVHMDVKADNVLVDAHGNCKLTDYGIAQL 945
>27405
          Length = 532

 Score = 41.2 bits (95), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 35/124 (28%), Positives = 56/124 (45%), Gaps = 3/124 (2%)
 Frame = -3

Query: 328 YAVVSEEPIYIVTEYMNKGSLLDFLKGE---TGKYLRLPQLVDMSAQIASGMAYVERMNY 384
           YA  + E +  + + MN G L   L      T K +R       +A++  G+ ++     
Sbjct: 353 YAFQTPEKLCFILDLMNGGDLHYHLSQHGVFTEKEVRF-----YAAEVMLGLEHMHSRFV 189

Query: 385 VHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIK 444
           V+RDL+ ANIL+ EN   +++D GLA      +  A  G      + APE  + G+    
Sbjct: 188 VYRDLKPANILLDENGHVRISDLGLACDFSKKKPHASVGTH---GYMAPEVLMKGQAYDS 18

Query: 445 SDVW 448
           S  W
Sbjct: 17  SADW 6
>29687
          Length = 434

 Score = 41.2 bits (95), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 21/55 (38%), Positives = 31/55 (56%)
 Frame = -2

Query: 90  ALYDYESRTETDLSFKKGERLQIVNNTEGDWWLAHSLSTGQTGYIPSNYVAPSDS 144
           AL+DY ++ E +LSF KG  +  V+  +G WW      T +  + PSNYV   D+
Sbjct: 286 ALHDYNAKREDELSFCKGAIITNVSRQDGGWWRG-DYGTKKQHWFPSNYVEEIDT 125
>16716
          Length = 934

 Score = 40.8 bits (94), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 23/84 (27%), Positives = 42/84 (50%)
 Frame = -1

Query: 56  PAAEPKLFGGFNSSDTVTSPQRAGPLAGGVTTFVALYDYESRTETDLSFKKGERLQIVNN 115
           P  EP+      + +   +P ++ P  GG +T +ALYDY++  + +L+F   + +  +  
Sbjct: 553 PQHEPEESPYEMADEEPAAPAQSQP--GGGSTAIALYDYQAADDDELTFDPDDVITDIEM 380

Query: 116 TEGDWWLAHSLSTGQTGYIPSNYV 139
            +  WW       G+ G  P+NYV
Sbjct: 379 IDDGWWRGS--CHGKNGLFPANYV 314
>05206
          Length = 1075

 Score = 40.4 bits (93), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 18/55 (32%), Positives = 30/55 (54%)
 Frame = +1

Query: 85  VTTFVALYDYESRTETDLSFKKGERLQIVNNTEGDWWLAHSLSTGQTGYIPSNYV 139
           + T  ALY +E+  E  +   + E +QI+   +GD W     + G  G++PS+YV
Sbjct: 88  IGTCRALYPFEAMNEGSVPMGENEEMQILEEDQGDGWTRVRKADGSEGFVPSSYV 252
>32000
          Length = 644

 Score = 40.4 bits (93), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 36/113 (31%), Positives = 55/113 (48%), Gaps = 4/113 (3%)
 Frame = -1

Query: 403 KVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRF-TIKSDVWSFGILLTELTTKG 461
           K+ADFGLAR+      T        + + APE  L  RF ++  D+WS G +  E+ T+ 
Sbjct: 569 KIADFGLARVFGLPVRTYTHEV-ITLWYRAPEILLGCRFYSVPVDIWSLGCIFVEMMTR- 396

Query: 462 RVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCW---RKEPEERPTF 511
           R  +PG  + E+ DQ+ R +R    P+          + W    K P+ +PTF
Sbjct: 395 RALFPG--DSEI-DQLYRIFRTLGTPD---------EKVWPGVSKLPDYKPTF 273
>35671
          Length = 567

 Score = 40.4 bits (93), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 17/47 (36%), Positives = 28/47 (59%)
 Frame = -3

Query: 478 ERGYRMPCPPECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYFTS 524
           ++G R+  P  C +  + +M QCW +  EERPTF+ L   +E+ + S
Sbjct: 565 QKGNRLAKPISCTDEAYKVMLQCWTESREERPTFKKLVPVMENLYRS 425
>18881
          Length = 762

 Score = 40.0 bits (92), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 24/66 (36%), Positives = 36/66 (54%)
 Frame = -3

Query: 170 PRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLV 229
           P GTFL+R + T+    C     + NA    V+H K+ +   G FY+     F+S+QQLV
Sbjct: 748 PDGTFLIRVTNTSARESCPQY*-YANA----VRHIKVNRNPQGRFYLADGHYFDSVQQLV 584

Query: 230 AYYSKH 235
            +Y K+
Sbjct: 583 EHYEKN 566

 Score = 33.1 bits (74), Expect = 0.33,   Method: Compositional matrix adjust.
 Identities = 16/47 (34%), Positives = 24/47 (51%), Gaps = 2/47 (4%)
 Frame = -3

Query: 100 TDLSFKKGERLQIV--NNTEGDWWLAHSLSTGQTGYIPSNYVAPSDS 144
           T ++ K  +R+ I+  N  +  WW   +L T + GY P  YV   DS
Sbjct: 442 TQVTLKLNDRISILSKNGQDKGWWKGENLRTKKVGYFPLAYVDEEDS 302
>26711
          Length = 405

 Score = 40.0 bits (92), Expect = 0.002,   Method: Composition-based stats.
 Identities = 34/111 (30%), Positives = 53/111 (47%), Gaps = 3/111 (2%)
 Frame = -2

Query: 371 QIASGMAYVERMNYVHRDLRAANILV-GENL-VCKVADFGLAR-LIEDNEYTARQGAKFP 427
           Q+   + +V     VH DL+ +N+L+ G+ L   ++ DFGLAR L    E     G    
Sbjct: 392 QVLDILQHVHAQGVVHMDLKPSNLLLSGDKLDSVQLIDFGLARKLYPPQETFLNHGTP-- 219

Query: 428 IKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVE 478
             +T+PEA      +  SDVW  G+L   L + G+ P+      E L + +
Sbjct: 218 -GFTSPEALDVKPISTASDVWGVGVLAYILLS-GQSPFQADSATESLKKTQ 72
>18481
          Length = 437

 Score = 39.3 bits (90), Expect = 0.004,   Method: Composition-based stats.
 Identities = 31/113 (27%), Positives = 59/113 (52%), Gaps = 5/113 (4%)
 Frame = -1

Query: 312 EAQVMKKL-RHEKLVQLYAVVSEEPI-YIVTEYMNKGSLLDFLKGETGKYLRLPQLVDMS 369
           EA+V +++ RH  L  +Y   +E+    +V E +  G  L+ L     +   L  ++ +S
Sbjct: 350 EAKVYEQIGRHPGLPTMYHYGTEKHFNALVMELL--GPSLEELFVICKRRFTLKTILMVS 177

Query: 370 AQIASGMAYVERMNYVHRDLRAANILVGENLVCK---VADFGLARLIEDNEYT 419
            Q+ S + ++ +  ++HRDL+  N L+G    C    + DFGL++  +D + T
Sbjct: 176 DQLLSRLEFIHQKCFIHRDLKPDNFLMGLGRHCHRLYIIDFGLSKRYKDTQGT 18
>12786
          Length = 460

 Score = 39.3 bits (90), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 28/108 (25%), Positives = 51/108 (47%), Gaps = 22/108 (20%)
 Frame = -3

Query: 385 VHRDLRAAN-ILVGENLVCKVADFGLARLIEDNEYTARQGAKFPI-KWTAPEAALYG--- 439
           +H DL+ AN +LV  NL  K+ DFG+A  ++ ++ +  + ++     + +PEA +     
Sbjct: 344 IHSDLKPANFMLVAGNL--KLIDFGIANTLQQDKTSVLKDSRVGTPSYMSPEAIMAACDD 171

Query: 440 -----------------RFTIKSDVWSFGILLTELTTKGRVPYPGMVN 470
                            +  ++SDVWS G +L  +   GR P+  + N
Sbjct: 170 SADDSMEEDGHRTKPKYKVGVRSDVWSLGCILYNMVY-GRTPFQHIKN 30
>28638
          Length = 1458

 Score = 38.9 bits (89), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 26/93 (27%), Positives = 47/93 (50%), Gaps = 4/93 (4%)
 Frame = -1

Query: 371 QIASGMAYVE--RMNYVHRDLRAANILVG--ENLVCKVADFGLARLIEDNEYTARQGAKF 426
           Q+ + + ++    MN +H DL+  NIL+   +    K+ DFG +  +    Y   Q ++F
Sbjct: 813 QLCTALLFLATPEMNIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQ-SRF 637

Query: 427 PIKWTAPEAALYGRFTIKSDVWSFGILLTELTT 459
              + +PE  L   + +  D+WS G +L E+ T
Sbjct: 636 ---YRSPEVLLGVPYDLAIDMWSLGCILVEMHT 547
>38046
          Length = 446

 Score = 38.5 bits (88), Expect = 0.007,   Method: Composition-based stats.
 Identities = 16/28 (57%), Positives = 21/28 (75%)
 Frame = -1

Query: 372 IASGMAYVERMNYVHRDLRAANILVGEN 399
           IA  MAY+E+ N++HR+L   NILVG N
Sbjct: 98  IADAMAYMEKENFIHRNLGDRNILVGPN 15
>28095
          Length = 597

 Score = 37.4 bits (85), Expect = 0.014,   Method: Compositional matrix adjust.
 Identities = 17/50 (34%), Positives = 26/50 (52%)
 Frame = +3

Query: 90  ALYDYESRTETDLSFKKGERLQIVNNTEGDWWLAHSLSTGQTGYIPSNYV 139
           A+YDY++    ++SF  G+ +      +  W       TGQ G +PSNYV
Sbjct: 270 AMYDYQAADSDEVSFNDGDTIIECQPVDAGWMTGRVERTGQYGMLPSNYV 419
>29636
          Length = 354

 Score = 37.4 bits (85), Expect = 0.014,   Method: Composition-based stats.
 Identities = 30/107 (28%), Positives = 47/107 (43%), Gaps = 7/107 (6%)
 Frame = +1

Query: 70  DTVTSPQRAGPLAGGVTTFVALYDYESRT-------ETDLSFKKGERLQIVNNTEGDWWL 122
           DT   P       G +    AL++Y+          E  +SF KG+ L  +  ++ +WW 
Sbjct: 43  DTTAKP-------GDIMHLRALFNYDPEDDPYIPCRELGISFLKGDILHAIQLSDSNWWQ 201

Query: 123 AHSLSTGQTGYIPSNYVAPSDSIQAEEWYFGKITRRESERLLLNAEN 169
           AH    G+  ++ +  + PS + Q +         RES R  LNAEN
Sbjct: 202 AH--REGEDAHMLAGLI-PSKAFQEQ---------RESVRQQLNAEN 306
>07933
          Length = 728

 Score = 37.4 bits (85), Expect = 0.014,   Method: Compositional matrix adjust.
 Identities = 15/30 (50%), Positives = 19/30 (63%)
 Frame = +3

Query: 486 PPECPESLHDLMCQCWRKEPEERPTFEYLQ 515
           P  CP  L+++M QCW  EP  RPTF  L+
Sbjct: 3   PNYCPNLLYNIMMQCWSAEPSARPTFHKLE 92
>21433
          Length = 590

 Score = 36.2 bits (82), Expect = 0.030,   Method: Compositional matrix adjust.
 Identities = 24/87 (27%), Positives = 39/87 (44%)
 Frame = +2

Query: 371 QIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKW 430
           Q++S + Y      +HRD++  N+L+G     K+ADFG +     +  T   G    + +
Sbjct: 191 QLSSALEYCHYRKVIHRDIKPENLLLGLKGDLKIADFGWSVHAPSSRRTTMCGT---LDY 361

Query: 431 TAPEAALYGRFTIKSDVWSFGILLTEL 457
             PE           D+WS G+L  E 
Sbjct: 362 LPPEMVEGKTHDENVDLWSLGVLCYEF 442
>01392
          Length = 1806

 Score = 36.2 bits (82), Expect = 0.033,   Method: Compositional matrix adjust.
 Identities = 32/115 (27%), Positives = 51/115 (44%), Gaps = 12/115 (10%)
 Frame = -1

Query: 371  QIASGMAYVERMNYVHRDLRAANIL---VGENLVCKVADFGLARLIE-DNEYTARQGAKF 426
             IA  + ++      HRDL+  NIL   + + +  K+ DF LA  I  D + T       
Sbjct: 1767 HIARALDFLHSKGIAHRDLKPENILCEHLDDVVPVKICDFDLASGISCDGDGTKTPELLT 1588

Query: 427  PI---KWTAPEA--ALYG---RFTIKSDVWSFGILLTELTTKGRVPYPGMVNREV 473
            P+   ++ APE   A  G    +  + D+WS GI+L  +   G  P+ G    + 
Sbjct: 1587 PVGSAEYMAPEVVDAWVGDSFSYDKRCDLWSLGIILY-IMLCGYPPFYGQCGEDC 1426
>13641
          Length = 2081

 Score = 36.2 bits (82), Expect = 0.034,   Method: Compositional matrix adjust.
 Identities = 17/42 (40%), Positives = 24/42 (57%), Gaps = 2/42 (4%)
 Frame = +2

Query: 99  ETDLSFKKGERLQIVNNTEGDWWLA--HSLSTGQTGYIPSNY 138
           E  LSF++G+ L IVN  +  WW A  H  +  + G IPS +
Sbjct: 212 EAGLSFQQGDILHIVNQEDAIWWQAYKHGDAKKRAGLIPSRH 337
>36481
          Length = 806

 Score = 36.2 bits (82), Expect = 0.035,   Method: Compositional matrix adjust.
 Identities = 40/152 (26%), Positives = 64/152 (42%), Gaps = 13/152 (8%)
 Frame = +2

Query: 257 LAKDAWEIPR-----ESLRLEVKLGQGCFGEVWM--GTWNGTTRVAIKTLKPGTMSPEAF 309
           + KD W   R       ++L    G+G FG+V        G   +A+K +K      EA 
Sbjct: 317 MRKDIWCTMRGTSSTNDMKLCPHWGEGTFGKVVQCKDLLKGDD-IALKIIKNVDKYREAA 493

Query: 310 LQEAQVMKKLR----HEK--LVQLYAVVSEEPIYIVTEYMNKGSLLDFLKGETGKYLRLP 363
             E  V++KLR    H K   VQ+           ++ +M   S+ DFLK  +     + 
Sbjct: 494 KLEINVLEKLREKDPHAKHMCVQMLDWFDYHGHVCISFHMLGLSVFDFLKDNSYGAYPIE 673

Query: 364 QLVDMSAQIASGMAYVERMNYVHRDLRAANIL 395
           Q+  +S Q+   + ++      H DL+  NIL
Sbjct: 674 QVRHISYQLCYAVNFLHENQLTHTDLKPENIL 769
>01494
          Length = 2122

 Score = 36.2 bits (82), Expect = 0.036,   Method: Compositional matrix adjust.
 Identities = 18/50 (36%), Positives = 28/50 (56%)
 Frame = +3

Query: 90  ALYDYESRTETDLSFKKGERLQIVNNTEGDWWLAHSLSTGQTGYIPSNYV 139
           AL+DY +  + +LSF KG  +  V+  +G WW     +  Q  + PSN+V
Sbjct: 318 ALHDYNANRDDELSFCKGAIITNVSRQDGGWWRGDYGAKKQH-WFPSNFV 464
>30740
          Length = 488

 Score = 36.2 bits (82), Expect = 0.037,   Method: Compositional matrix adjust.
 Identities = 16/44 (36%), Positives = 24/44 (54%)
 Frame = +2

Query: 92  YDYESRTETDLSFKKGERLQIVNNTEGDWWLAHSLSTGQTGYIP 135
           YD+  R   DL F KG+ L++++  E +WW A     G+ G  P
Sbjct: 203 YDFSGRDPEDLPFSKGDILELISKDEEEWWTARD-KHGRVGQDP 331
>17286
          Length = 489

 Score = 35.8 bits (81), Expect = 0.048,   Method: Composition-based stats.
 Identities = 14/50 (28%), Positives = 30/50 (60%)
 Frame = +3

Query: 90  ALYDYESRTETDLSFKKGERLQIVNNTEGDWWLAHSLSTGQTGYIPSNYV 139
           A+YD+   ++ +L F++G+ + +++  + +W+       G+ GY P NYV
Sbjct: 36  AIYDFLPESDGELGFQEGDMITLISQVDENWF--EGSVHGKVGYFPINYV 179
>17516
          Length = 453

 Score = 35.4 bits (80), Expect = 0.051,   Method: Compositional matrix adjust.
 Identities = 30/102 (29%), Positives = 44/102 (43%), Gaps = 7/102 (6%)
 Frame = -3

Query: 432 APEAALY-GRFTIKSDVWSFGILLTEL--TTKGRVPYPGMVNREVLDQVERGYR----MP 484
           APE  L  G++ +K+DV+S  I+L EL             +   + D V+ G R    M 
Sbjct: 415 APEVLLQKGQYDMKADVYSLAIILWELWYGQDAADHISSHLFGRLEDAVQAGLRPSVTMT 236

Query: 485 CPPECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYFTSTE 526
           C P  P+    L+   W     +RPT      F ED+   T+
Sbjct: 235 CKP--PDDWLKLLQSGWEFHASKRPTSRDAAEFFEDFLERTK 116
>20152
          Length = 445

 Score = 34.3 bits (77), Expect = 0.14,   Method: Composition-based stats.
 Identities = 20/71 (28%), Positives = 33/71 (46%)
 Frame = +1

Query: 446 DVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKEP 505
           DVWS G++L  L   G  P+    + E L  +    R   PP       DL+ +  ++EP
Sbjct: 43  DVWSLGVILYMLVV-GEAPFQEANDSETLTMI-MDCRYQIPPHISHKCQDLIEKMLQREP 216

Query: 506 EERPTFEYLQA 516
            +R +  ++ A
Sbjct: 217 VDRASLPHILA 249
>13664
          Length = 507

 Score = 33.9 bits (76), Expect = 0.19,   Method: Compositional matrix adjust.
 Identities = 14/45 (31%), Positives = 26/45 (57%)
 Frame = +2

Query: 89  VALYDYESRTETDLSFKKGERLQIVNNTEGDWWLAHSLSTGQTGY 133
           VALYDY+++   +L+   G+ + +++     WW+   L  GQ G+
Sbjct: 374 VALYDYKAQRSDELTILSGDVIMLLHKDSESWWMGELLD-GQQGF 505
>37260
          Length = 401

 Score = 32.3 bits (72), Expect = 0.43,   Method: Composition-based stats.
 Identities = 16/56 (28%), Positives = 29/56 (51%)
 Frame = -1

Query: 150 WYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYK 205
           WY+G ++  E+E  L++  +  G+FLVR+S        LS     +     ++H+K
Sbjct: 182 WYWGPLSYEEAESKLMDKRD--GSFLVRDSSNENYILSLSFKSMGHVHHTRIEHHK 21
>27287
          Length = 514

 Score = 32.0 bits (71), Expect = 0.58,   Method: Compositional matrix adjust.
 Identities = 13/40 (32%), Positives = 22/40 (55%)
 Frame = -2

Query: 486 PPECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYFTST 525
           PP     +  +M  CW+++P +RP+F  L   L+   TS+
Sbjct: 504 PPYASSEMFGIMHSCWQEDPNDRPSFSRLVQELDKMLTSS 385
>29360
          Length = 363

 Score = 32.0 bits (71), Expect = 0.73,   Method: Composition-based stats.
 Identities = 26/113 (23%), Positives = 52/113 (46%), Gaps = 6/113 (5%)
 Frame = +3

Query: 290 GTTR-VAIKTLKPGTMSPEAFLQEAQVMKKLRHE-----KLVQLYAVVSEEPIYIVTEYM 343
           GT+  VAIK LK           E  ++++L  E       V+ +     +    +   M
Sbjct: 21  GTSEIVAIKILKNHPSYARQGQIEVSILQRLSQESADDYNFVRAFECFQHKNHTCLVFEM 200

Query: 344 NKGSLLDFLKGETGKYLRLPQLVDMSAQIASGMAYVERMNYVHRDLRAANILV 396
            + +L DFLK    + L L  +  ++ Q+ + +  ++++  +H DL+  NI++
Sbjct: 201 LEQNLYDFLKQNKFQPLPLKYIRPITQQVLTALRKLKQLGLIHADLKPENIML 359
>02638
          Length = 1490

 Score = 30.4 bits (67), Expect = 2.0,   Method: Compositional matrix adjust.
 Identities = 24/94 (25%), Positives = 46/94 (48%), Gaps = 7/94 (7%)
 Frame = +1

Query: 428 IKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPC-- 485
           I + APE      +    DVWS G ++ E+ T  R P+    + ++ + +   +++    
Sbjct: 28  IAFMAPEVLRGESYGRACDVWSVGCVMIEMCT-CRPPW---NSHDISNHLALIFKIASSV 195

Query: 486 -PPECPESL----HDLMCQCWRKEPEERPTFEYL 514
            PP  PE++     DLM +C  ++ + RP+ + L
Sbjct: 196 DPPPIPENMSPPVRDLMLRCLEQDSDFRPSAKDL 297
>23319
          Length = 2235

 Score = 29.6 bits (65), Expect = 2.9,   Method: Compositional matrix adjust.
 Identities = 14/51 (27%), Positives = 26/51 (50%)
 Frame = +3

Query: 433 PEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRM 483
           P+      ++   D+WS G +  EL   GR  +PG    +  DQ++R +++
Sbjct: 3   PDVYXAKMYSTSIDMWSAGCIFAELANAGRPLFPG---NDDDDQLKRIFKL 146
>32357
          Length = 625

 Score = 29.6 bits (65), Expect = 3.2,   Method: Compositional matrix adjust.
 Identities = 14/43 (32%), Positives = 23/43 (53%), Gaps = 1/43 (2%)
 Frame = -2

Query: 270 RLEVKLGQGCFGEVWMGTWNGT-TRVAIKTLKPGTMSPEAFLQ 311
           RL  K+G G FGE+++G  N +   VA+K        P+ + +
Sbjct: 429 RLMKKIGSGSFGEIYLGVHNTSGEEVAVKLELKNAKHPQLYYE 301
>15741
          Length = 402

 Score = 28.9 bits (63), Expect = 4.9,   Method: Composition-based stats.
 Identities = 12/25 (48%), Positives = 16/25 (64%)
 Frame = -3

Query: 371 QIASGMAYVERMNYVHRDLRAANIL 395
            +A GMA+V     VHRD+ A N+L
Sbjct: 76  HVARGMAHVANNKIVHRDVAARNVL 2
>30231
          Length = 340

 Score = 28.9 bits (63), Expect = 5.9,   Method: Composition-based stats.
 Identities = 24/86 (27%), Positives = 34/86 (39%), Gaps = 5/86 (5%)
 Frame = -2

Query: 172 GTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSR-----TQFNSLQ 226
           G+FLVR+SE+   AY L +        L V  Y+I     G   + S        F  L 
Sbjct: 249 GSFLVRDSESVSNAYVLCL-----LFQLRVHQYRILPDKDGRLSVQSEGDMQPLSFIDLP 85

Query: 227 QLVAYYSKHADGLCHRLTTVCPTSKP 252
            L+  Y    D    +   +CP  +P
Sbjct: 84  SLIQVYISKGD----KNGLICPLRRP 19
>28929
          Length = 424

 Score = 28.5 bits (62), Expect = 7.2,   Method: Compositional matrix adjust.
 Identities = 19/56 (33%), Positives = 25/56 (44%)
 Frame = -3

Query: 88  FVALYDYESRTETDLSFKKGERLQIVNNTEGDWWLAHSLSTGQTGYIPSNYVAPSD 143
           F AL D  S T T   F K  R  + + T   WW+A +      G +PS    PS+
Sbjct: 218 FEALCDRRSETVTLFLFFK--RSWVGSETAPRWWIAKTWRNFDAGCVPSPNPKPSN 57
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6679299|ref|NP_032857.1| prohibitin [Mus musculus]
         (272 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

20881                                                                 325   1e-89
07529                                                                 234   4e-62
21462                                                                  28   4.5  
>20881
          Length = 2017

 Score =  325 bits (834), Expect = 1e-89,   Method: Compositional matrix adjust.
 Identities = 155/215 (72%), Positives = 178/215 (82%)
 Frame = +1

Query: 58  IPWVQKPIIFDCRSRPRNVPVITGSKDLQNVNITLRILFRPVASQLPRIYTSIGEDYDER 117
           IPWVQKPIIFDCRSRPRNVPV+TGSKDLQNVNITLRILFRP    LP+I+T++G DYDER
Sbjct: 208 IPWVQKPIIFDCRSRPRNVPVVTGSKDLQNVNITLRILFRPQVPSLPKIFTNLGTDYDER 387

Query: 118 VLPSITTEILKSVVARFDAGELITQRELVSRQVSDDLTERAATFGLILDDVSLTHLTFGK 177
           VLPSIT E+LK++VA+FDA ELITQRELVS++VS++LT+RA  FGL+LDD+SLTHLTFG+
Sbjct: 388 VLPSITNEVLKAIVAQFDASELITQRELVSQKVSEELTDRALQFGLLLDDISLTHLTFGR 567

Query: 178 EFTXXXXXXXXXXXXXXXXXFVVEKAEQQKKAAIISAEGDSKAAELIANSLATAGDGLIE 237
           EFT                 FVVEKAEQQKKAA+ISAEGDS AAE +A +   AG+GL+E
Sbjct: 568 EFTEAVESKQVAQQEAERARFVVEKAEQQKKAAVISAEGDSLAAEQLAKAFGEAGEGLVE 747

Query: 238 LRKLEAAEDIAYQLSRSRNITYLPAGQSVLLQLPQ 272
           LRKLEAAEDIAYQLSRSRN+ YLP GQ  LL LPQ
Sbjct: 748 LRKLEAAEDIAYQLSRSRNVVYLPQGQQTLLSLPQ 852

 Score = 70.5 bits (171), Expect = 7e-13,   Method: Compositional matrix adjust.
 Identities = 46/88 (52%), Positives = 54/88 (61%)
 Frame = +2

Query: 1   MAAKVFESIGKFGLALAVAGGVVNSALYNVDAGHRAVIFDRFRGVQDIVVGEGTHFLIPW 60
           MA ++F S+ K G+ +AV GGVV SALYNVD GHRAVIFDRFRGVQD V GEGTH     
Sbjct: 35  MAQRLFSSLSKLGVGIAVVGGVVQSALYNVDGGHRAVIFDRFRGVQDAVSGEGTH----- 199

Query: 61  VQKPIIFDCRSRPRNVPVITGSKDLQNV 88
                          VP   GSK+L ++
Sbjct: 200 ---------------VPRFPGSKNLSSL 238
>07529
          Length = 1399

 Score =  234 bits (596), Expect = 4e-62,   Method: Compositional matrix adjust.
 Identities = 113/220 (51%), Positives = 157/220 (71%)
 Frame = +2

Query: 44  GVQDIVVGEGTHFLIPWVQKPIIFDCRSRPRNVPVITGSKDLQNVNITLRILFRPVASQL 103
           GVQ+ V  EG HF +PW Q PII+D RSRPR +   TGSKDLQ VNI+LR+L RP+ASQL
Sbjct: 5   GVQEDVYVEGLHFRVPWFQYPIIYDIRSRPRKITSPTGSKDLQMVNISLRVLSRPIASQL 184

Query: 104 PRIYTSIGEDYDERVLPSITTEILKSVVARFDAGELITQRELVSRQVSDDLTERAATFGL 163
           P +Y S+G DYDERVLPSI  E+LKSVVA+F+A +LITQR+ VS  +  +LTERA  F +
Sbjct: 185 PHVYRSLGTDYDERVLPSICNEVLKSVVAKFNASQLITQRQQVSLLIRRELTERAKDFNI 364

Query: 164 ILDDVSLTHLTFGKEFTXXXXXXXXXXXXXXXXXFVVEKAEQQKKAAIISAEGDSKAAEL 223
           ILDDVS+T L+FG+E+T                 F+VEKA+Q+K+  ++ A+G+++AA+L
Sbjct: 365 ILDDVSITELSFGREYTAAVESKQVAQQEAQRAQFLVEKAKQEKQQKMVQADGEAQAAKL 544

Query: 224 IANSLATAGDGLIELRKLEAAEDIAYQLSRSRNITYLPAG 263
           I  ++  A  G ++LRK+ AA++I+  +++S+N  YL A 
Sbjct: 545 IGQAV-QANPGFLKLRKIRAAQNISRTVAQSQNRVYLNAS 661
>21462
          Length = 1155

 Score = 28.1 bits (61), Expect = 4.5,   Method: Compositional matrix adjust.
 Identities = 25/85 (29%), Positives = 43/85 (50%), Gaps = 7/85 (8%)
 Frame = -1

Query: 87  NVNITLR-ILFRPVASQLPRIY-TSIGED---YDERVLPSITTEILKSVVARFDAGELIT 141
           NV ++L  +L  P + QL   Y   +G+      ER++ S+T  +   V+ + DA  + T
Sbjct: 261 NVYMSLSPVLIWPQSGQLTT*Y*NRVGDR**IQKERIMRSVTARLAGVVLRQHDASHIAT 82

Query: 142 QRELVSRQVSDDLT-ERAAT-FGLI 164
              LVS++++  L  E   T FG +
Sbjct: 81  MDCLVSKEIAQCLQIENCCTGFGYL 7
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|11863684|emb|CAC18811.1| neurobeachin [Mus musculus]
         (2936 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

00139                                                                 181   2e-89
27225                                                                 162   2e-39
34256                                                                  77   1e-29
19571                                                                  83   2e-15
30256                                                                  53   2e-06
00561                                                                  42   0.003
27465                                                                  39   0.033
21105                                                                  38   0.047
12806                                                                  38   0.071
18981                                                                  35   0.43 
38177                                                                  34   0.69 
03395                                                                  32   3.2  
16738                                                                  31   7.5  
02147                                                                  31   8.9  
>00139
          Length = 1653

 Score =  181 bits (459), Expect(2) = 2e-89,   Method: Compositional matrix adjust.
 Identities = 82/132 (62%), Positives = 107/132 (81%)
 Frame = +2

Query: 1307 RRQFSPGPRTTMFRIPEFKWSPMHQRLLTDLLFALETDVHVWRSHSTKSVMDFVNSNENI 1366
            R  FSPGPR   FRIPEF+WS +HQ+LL+DLLFA+ETDV VW+SHS+K+V+DFVN++EN 
Sbjct: 719  RAIFSPGPRAPPFRIPEFRWSYLHQKLLSDLLFAVETDVQVWKSHSSKNVIDFVNASENH 898

Query: 1367 IFVHNTIHLISQMVDNIIIACGGILPLLSAATSPTGSKTELENIEVTQGMSAETAVTFLS 1426
            I+V N  H+ISQ+ DN+I +CGG+LPLL+AATSP G   E++ +E  QG+S E AV+ L 
Sbjct: 899  IYVVNVTHMISQLADNLITSCGGLLPLLAAATSPNG---EIDILEPNQGLSIEQAVSILQ 1069

Query: 1427 RLMAMVDVLVFA 1438
            R+MAM D+LVFA
Sbjct: 1070 RIMAMTDILVFA 1105

 Score =  169 bits (428), Expect(2) = 2e-89,   Method: Compositional matrix adjust.
 Identities = 88/151 (58%), Positives = 107/151 (70%), Gaps = 14/151 (9%)
 Frame = +3

Query: 1439 SSLNFSEIEAEKNMSSGGLMRQCLRLVCCVAVRNCLECRQR---------QRDRGSKSSH 1489
            SS NF+E+E EKNM SGG++RQCLRLVC  AVRNCLECR R              S S  
Sbjct: 1107 SSTNFAELEQEKNMPSGGILRQCLRLVCTAAVRNCLECRHRYSRPPSEPPSPGGSSTSGA 1286

Query: 1490 GSSKPQEAP---HSVTAAS--ASKTPLENVPGNLSPIKDPDRLLQDVDINRLRAVVFRDV 1544
               KP        S+   S  ++K  +EN+ G ++PIKDP++LLQD+DINRLRAVV+RDV
Sbjct: 1287 AGGKPVNGVDPIQSLIGGSHPSTKNIVENLAGQVAPIKDPEKLLQDMDINRLRAVVYRDV 1466

Query: 1545 DDSKQAQFLALAVVYFISVLMVSKYRDILEP 1575
            +++KQAQFLALA+VYF SVLMVSKYRDILEP
Sbjct: 1467 EETKQAQFLALAIVYFTSVLMVSKYRDILEP 1559

 Score =  103 bits (256), Expect = 1e-21,   Method: Compositional matrix adjust.
 Identities = 49/104 (47%), Positives = 74/104 (71%), Gaps = 4/104 (3%)
 Frame = +2

Query: 896 SSEEQKITEMVYNIFRILLYHAIKYEWGGWRVWVDTLSIAHSKVTYEAHKEYLAKMYEEY 955
           +SE+QKIT+MV  +FR+LL+HAIK+E+GGWRVW+DTL+I HSKV +E   ++++KMY +Y
Sbjct: 2   NSEQQKITDMVMALFRMLLHHAIKFEFGGWRVWIDTLAILHSKVAFEDFNKHMSKMYHQY 181

Query: 956 QRQEEENIXXXXXXN---VSTISGLSSQTAG-AKGGMEIREIED 995
           ++Q  ++I          +STISG+ +Q     K  ++I EI D
Sbjct: 182 EQQRTDDIVDPSERQQRPISTISGIGAQEKPLPKSTVQISEITD 313
>27225
          Length = 391

 Score =  162 bits (410), Expect = 2e-39,   Method: Compositional matrix adjust.
 Identities = 75/130 (57%), Positives = 100/130 (76%)
 Frame = +2

Query: 631 LQLMHTLKYYYWVINPADSSGIAPKGLDGPRPSQKEIISLRAFMLLFLKQLILKDRGVKE 690
           LQ MH+LK+YYWV++P D SGI PKGLDG RP+  EI+ LR+FMLL+L++LI+K +G+ E
Sbjct: 2   LQTMHSLKFYYWVVSPQDRSGIIPKGLDGARPTHDEIVKLRSFMLLYLRELIVKGQGILE 181

Query: 691 DELQSILNYLLTMHEDENIHDVLQLLVALMSEHPASMIPAFDQRNGIRVIYKLLASKSES 750
           DELQS+LNYL T+HED+NI DVL+LLV LM++HPASM+PAFD+        +      E 
Sbjct: 182 DELQSMLNYLTTLHEDDNIQDVLELLVELMAQHPASMVPAFDREERHHHCLQAAGIAEED 361

Query: 751 IWVQALKVLG 760
           I + AL++LG
Sbjct: 362 IRLLALRLLG 391
>34256
          Length = 485

 Score = 76.6 bits (187), Expect(2) = 1e-29,   Method: Compositional matrix adjust.
 Identities = 44/115 (38%), Positives = 63/115 (54%), Gaps = 9/115 (7%)
 Frame = -1

Query: 2054 DFWRLDYWEDDLXXXXXFVRNAFGSTHAEALLKSAVEYGTEEDVV-KSKKAFRS------ 2106
            +FW+LD WEDD       VRN  GSTH++A LK+A+E+G  ED + ++++AF +      
Sbjct: 335  EFWKLDVWEDDSRRRRRLVRNPLGSTHSQATLKAAIEHGATEDAINQAREAFHAHLSHLR 156

Query: 2107 --QAIVNQNSETELMLEGDDDAVSLLQEKEIDNLAGPVVLSTPAQLIAPVVVAKG 2159
              Q  +   ++ ELM+E  D       E       GPV LST  +L+AP V  KG
Sbjct: 155  KVQKEITDYTDEELMMEEKD----FEPEFSGHYCVGPVALSTACKLVAPGVSVKG 3

 Score = 74.3 bits (181), Expect(2) = 1e-29,   Method: Composition-based stats.
 Identities = 31/46 (67%), Positives = 38/46 (82%)
 Frame = -3

Query: 2005 REEEKMCDHLISAAKHRDHVTANQLKQKILNILTNKHGAWGAVSHS 2050
            REEEK+CDHLI +AK RDH  A +LK+K++NILTNKHGAWG  + S
Sbjct: 483  REEEKLCDHLIKSAKRRDHSVAYKLKEKVINILTNKHGAWGQAATS 346
>19571
          Length = 457

 Score = 83.2 bits (204), Expect = 2e-15,   Method: Composition-based stats.
 Identities = 53/157 (33%), Positives = 73/157 (46%), Gaps = 6/157 (3%)
 Frame = +2

Query: 2762 PRAVLTGHDHEVVCVSVCAELGLVISGAKEGPCLVHTITGDLLRALEGPENCLFPRLISV 2821
            P+AVLTGH  EV C+ V AELG+V+SG+K GP L     G        P     PR + V
Sbjct: 5    PKAVLTGHQAEVTCLGVIAELGIVVSGSKRGPVLGAHTDG------RPPAIARPPRQLPV 166

Query: 2822 SSEGHCII------YYERGRFSNFSINGKLLAQMEINDSTRAILLSSDGQNLVTGGDNGV 2875
                H +       +  +G         +  A      + +   LS DGQ ++  GD GV
Sbjct: 167  PPSHHHLP*SLHPGHLRQGPRLFLHRQRQAAALHAPQSNLQCQTLSRDGQYMIVSGDAGV 346

Query: 2876 VEVWQACDFKQLYIYPGCDAGIRAMDLSHDQRTLITG 2912
                   DF  LY +P CD+ IR++ L+HD +  I G
Sbjct: 347  WRCGATHDFTLLYTFPQCDSSIRSLALTHDHKFXIAG 457
>30256
          Length = 961

 Score = 53.1 bits (126), Expect = 2e-06,   Method: Composition-based stats.
 Identities = 61/204 (29%), Positives = 88/204 (43%), Gaps = 7/204 (3%)
 Frame = +3

Query: 2683 LICGFWDKSFRVYSTETGKLTQIVFGHWDVVTCLARSESYIGGDCYIVSGSRDATLLLWY 2742
            +I G  D+S +V++ +TG  T  ++GH   V CL+ S         +VSGSRDATL +W 
Sbjct: 81   VISGSTDRSLKVWNADTGVCTHTLYGHSSTVRCLSLSGK------KVVSGSRDATLRVWD 242

Query: 2743 WSGRHHIIGDNPNSSDYPAPRAVLTGHDHEVVCVSVCAELGLVISGAKEGPCLV-HTITG 2801
                H +               VL GH   V CV    +   V+SGA +    V    T 
Sbjct: 243  IESGHCL--------------NVLLGHMAAVRCVQYDGK--RVVSGAXDYTVRVWDPDTA 374

Query: 2802 DLLRALEGPENCLFPRLISVSSEGHCIIYYERGRFSNFSIN------GKLLAQMEINDST 2855
              L  L+G  N    R+ S+  +G   +Y   G     SI       GKL+  +  + S 
Sbjct: 375  SCLHTLQGHTN----RVYSLQFDG---VYVVSGSLDT-SIRVWDVRCGKLVHTLMGHQSL 530

Query: 2856 RAILLSSDGQNLVTGGDNGVVEVW 2879
             + L   D   LV+G  +  V+VW
Sbjct: 531  TSGLELKDNL-LVSGNADSTVKVW 599
>00561
          Length = 1003

 Score = 42.4 bits (98), Expect = 0.003,   Method: Composition-based stats.
 Identities = 26/68 (38%), Positives = 37/68 (54%)
 Frame = -3

Query: 2674 VVTADNRYILICGFWDKSFRVYSTETGKLTQIVFGHWDVVTCLARSESYIGGDCYIVSGS 2733
            V+++D  Y L  G WD++ R++    GK T+   GH   V  +A S      +  IVSGS
Sbjct: 845  VLSSDGNYAL-SGSWDQTLRLWDLAAGKTTRRFEGHTKDVLSVAFSAD----NRQIVSGS 681

Query: 2734 RDATLLLW 2741
            RD T+ LW
Sbjct: 680  RDKTIKLW 657

 Score = 31.2 bits (69), Expect = 7.0,   Method: Composition-based stats.
 Identities = 19/61 (31%), Positives = 30/61 (49%)
 Frame = -3

Query: 2729 IVSGSRDATLLLWYWSGRHHIIGDNPNSSDYPAPRAVLTGHDHEVVCVSVCAELGLVISG 2788
            I+S SRD TL++W       +  D   +  YP  R  L GH H +  V + ++    +SG
Sbjct: 965  IISASRDKTLIVW------KLTRDEDTNYGYPQKR--LYGHSHFISDVVLSSDGNYALSG 810

Query: 2789 A 2789
            +
Sbjct: 809  S 807
>27465
          Length = 658

 Score = 38.9 bits (89), Expect = 0.033,   Method: Compositional matrix adjust.
 Identities = 29/112 (25%), Positives = 51/112 (45%)
 Frame = -1

Query: 2683 LICGFWDKSFRVYSTETGKLTQIVFGHWDVVTCLARSESYIGGDCYIVSGSRDATLLLWY 2742
             I G +D++ +++ T + +    + GH +VV  +A +  +  GD  +++GS D T  LW 
Sbjct: 316  FITGSYDRTCKIWDTASAEELHTLEGHRNVVYAIAFNNPF--GD-KVITGSFDKTCKLW- 149

Query: 2743 WSGRHHIIGDNPNSSDYPAPRAVLTGHDHEVVCVSVCAELGLVISGAKEGPC 2794
                         S+        L GH  E+VCVS      L+ +G+ +  C
Sbjct: 148  -------------STADGKCYHTLRGHTAEIVCVSFNPSSTLIATGSMDTTC 32
>21105
          Length = 650

 Score = 38.1 bits (87), Expect = 0.047,   Method: Composition-based stats.
 Identities = 21/60 (35%), Positives = 30/60 (50%)
 Frame = +1

Query: 2682 ILICGFWDKSFRVYSTETGKLTQIVFGHWDVVTCLARSESYIGGDCYIVSGSRDATLLLW 2741
            I I    D+  R +   TGKL   +  H D VT LA   + +    Y++SGS D ++ LW
Sbjct: 106  ITITAHEDRHIRFFDNNTGKLIHAMVAHLDSVTSLAVDPNGL----YLLSGSHDCSIRLW 273
>12806
          Length = 961

 Score = 37.7 bits (86), Expect = 0.071,   Method: Compositional matrix adjust.
 Identities = 47/216 (21%), Positives = 88/216 (40%), Gaps = 20/216 (9%)
 Frame = +3

Query: 2728 YIVSGSRDATLLLWYWSGRHHIIGDNPNSSDYPAPRAVLTGHDHEVVCVSVCAELGLVIS 2787
            +++SG RD  +++W    +     D      +  PR  LTGH H +  +++ A+    +S
Sbjct: 51   FLISGGRDNNIIVWDL*PKK----DGDEDQTWGVPRKTLTGHSHFISDLALSADSRFALS 218

Query: 2788 GA----------KEGPCLVHTI--TGDLLRALEGPENCLFPRLISVSSEGHCIIYYERGR 2835
             +          K+G      I  T D+L     P+N    R I+             GR
Sbjct: 219  SSWDATLRLWDIKKGSTTSRFINHTRDVLTVAFSPDN----RQIASG-----------GR 353

Query: 2836 FSN---FSINGKLLAQMEIN---DSTRAILLSSDGQN--LVTGGDNGVVEVWQACDFKQL 2887
              N   ++I G+    ++ N   D    +    D +N  +V+  ++  ++VW        
Sbjct: 354  DKNLKIWNIMGECKYTVDANAHTDWVTCVRFHQDTKNPIVVSASNDKTIKVWDNHTMTLK 533

Query: 2888 YIYPGCDAGIRAMDLSHDQRTLITGMASGSIVAFNI 2923
              + G  A I A+D+S +   L++G   G  + +N+
Sbjct: 534  NTFVGHKAQITALDMSTNY--LVSGSKDGIAMTWNV 635
>18981
          Length = 407

 Score = 35.0 bits (79), Expect = 0.43,   Method: Composition-based stats.
 Identities = 24/94 (25%), Positives = 38/94 (40%)
 Frame = -2

Query: 2683 LICGFWDKSFRVYSTETGKLTQIVFGHWDVVTCLARSESYIGGDCYIVSGSRDATLLLWY 2742
            ++ G WDK+  V+  +TG+    + GH + +T +   E         VSGS D  +  W 
Sbjct: 259  VVSGSWDKTLIVWEVDTGRPVHQLHGHTEAITAVQFDEG------KAVSGSADGDVRTWA 98

Query: 2743 WSGRHHIIGDNPNSSDYPAPRAVLTGHDHEVVCV 2776
                  ++              + TG D EV CV
Sbjct: 97   LDTGQCLL-------------TMTTGQDIEVYCV 35
>38177
          Length = 430

 Score = 34.3 bits (77), Expect = 0.69,   Method: Compositional matrix adjust.
 Identities = 19/70 (27%), Positives = 32/70 (45%)
 Frame = +3

Query: 2857 AILLSSDGQNLVTGGDNGVVEVWQACDFKQLYIYPGCDAGIRAMDLSHDQRTLITGMASG 2916
             +  + +G+ LVTG  +G   +W    F    I    D  +RAM  S+  + ++T   SG
Sbjct: 3    CLAWTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDVSVRAMRWSNHDQWMVTADHSG 182

Query: 2917 SIVAFNIDFN 2926
             I  +  + N
Sbjct: 183  YIKYWQSNMN 212
>03395
          Length = 2795

 Score = 32.3 bits (72), Expect = 3.2,   Method: Composition-based stats.
 Identities = 19/64 (29%), Positives = 35/64 (54%), Gaps = 2/64 (3%)
 Frame = +2

Query: 2819 ISVSSEGHCIIYYERGRFSNFSINGKLLAQMEINDS--TRAILLSSDGQNLVTGGDNGVV 2876
            I  S   H I Y+E G       +G LL ++E + +     I +  DGQ ++TGG++ ++
Sbjct: 314  ILTSGTDHKIGYWEVG-------DGGLLRELEGSQTGAINTIDIDRDGQTILTGGEDSLL 472

Query: 2877 EVWQ 2880
            ++W+
Sbjct: 473  KLWR 484
>16738
          Length = 737

 Score = 30.8 bits (68), Expect = 7.5,   Method: Composition-based stats.
 Identities = 23/107 (21%), Positives = 42/107 (39%), Gaps = 6/107 (5%)
 Frame = -3

Query: 1276 TQAVQGRSSTQQDRDLRVD-----LGFRGMPMTEEQRRQFSPGPRTTMFRIPEFKWSPMH 1330
            T  + GRS   +    R+       G RG   T + R  ++P P  T          P +
Sbjct: 564  THTINGRSQYTKSSRSRLSGQHNHTGVRGHTHTRQTRTLYTPAPNAT----------PCN 415

Query: 1331 QRLLTDLLFALETDVHVW-RSHSTKSVMDFVNSNENIIFVHNTIHLI 1376
                T L     T ++    +H+  + +  +N N+  +++H   HL+
Sbjct: 414  XHTHTHLXXXAHTHLYTCAHTHTGDTHIKLINKNDTHMYIHIYTHLV 274
>02147
          Length = 1547

 Score = 30.8 bits (68), Expect = 8.9,   Method: Compositional matrix adjust.
 Identities = 21/60 (35%), Positives = 27/60 (45%)
 Frame = +2

Query: 2682 ILICGFWDKSFRVYSTETGKLTQIVFGHWDVVTCLARSESYIGGDCYIVSGSRDATLLLW 2741
              + G  D     +  ETGK  +   GH+  V C+  S     G+ Y  SGS D TL LW
Sbjct: 710  FFVAGGEDFKMYKFDYETGKEIESFKGHFGPVHCVRFSPD---GELY-ASGSEDGTLRLW 877
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6755198|ref|NP_036098.1| proteasome (prosome,
macropain) subunit, alpha type 6 [Mus musculus]
         (246 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

04255                                                                 323   3e-89
14551                                                                 139   9e-34
02448                                                                 132   1e-31
00789                                                                 132   1e-31
24591                                                                 131   2e-31
17033                                                                 127   4e-30
20771                                                                 118   2e-27
11023                                                                  97   6e-21
19133                                                                  58   3e-09
28971                                                                  52   2e-07
15509                                                                  28   2.9  
33143                                                                  28   3.9  
12467                                                                  27   9.3  
>04255
          Length = 1758

 Score =  323 bits (829), Expect = 3e-89,   Method: Compositional matrix adjust.
 Identities = 158/246 (64%), Positives = 187/246 (76%)
 Frame = -2

Query: 1    MSRGSSAGFDRHITIFSPEGRLYQVEYAFKAINQGGLTSVAVRGKDCAVIVTQKKVPDKL 60
            MSRGSSAG    +  FS   ++       +    G       + K        +KVPDKL
Sbjct: 1628 MSRGSSAGLTVSLQSFS*R-QIVSSRVCLQGYQPGRTDFCGCQRKRQRCYCHTEKVPDKL 1452

Query: 61   LDSSTVTHLFKITESIGCVMTGMTADSRSQVQRARYEAANWKYKYGYEIPVDMLCKRIAD 120
            LD +TVTHL+ +TE IGCVMTGM ADS+SQVQRARYEAA WKY YGY+IPVDMLCKRIA+
Sbjct: 1451 LDPTTVTHLYSLTERIGCVMTGMIADSQSQVQRARYEAAKWKYTYGYDIPVDMLCKRIAN 1272

Query: 121  ISQVYTQNAEMRPLGCCMILIGIDEEQGPQVYKCDPAGYYCGFKATAAGVKQTESTSFLE 180
            I+QVYTQ+AEMRPLGCCMILIG D+E+GP+VYK DPAGYYCGFKAT+AG KQ E+  FLE
Sbjct: 1271 INQVYTQSAEMRPLGCCMILIGYDDEKGPEVYKTDPAGYYCGFKATSAGSKQLEANGFLE 1092

Query: 181  KKVKKKFDWTFEQTVETAITCLSTVLSIDFKPSEIEVGVVTVENPKFRILTEAEIDAHLV 240
            KK+KKK D+T+ +  E AITCLSTVLS DFK SE+EVG+VT +NP FRILTEA+ID HL 
Sbjct: 1091 KKIKKKQDFTYNEAAEIAITCLSTVLSADFKASEVEVGIVTKDNPNFRILTEADIDVHLT 912

Query: 241  ALAERD 246
            A+AE+D
Sbjct: 911  AIAEKD 894
>14551
          Length = 1344

 Score =  139 bits (351), Expect = 9e-34,   Method: Compositional matrix adjust.
 Identities = 79/232 (34%), Positives = 124/232 (53%), Gaps = 1/232 (0%)
 Frame = +3

Query: 13  ITIFSPEGRLYQVEYAFKAINQGGLTSVAVRGKDCAVIVTQKKVPDKLLDSSTVTHLFKI 72
           +T FSP G+L Q+EYA  A+  G   SV ++  +  V+ T+KK      D  ++  +  I
Sbjct: 165 LTTFSPSGKLVQIEYALAAVGAGA-PSVGIKATNGVVLATEKKQKSVXYDEHSINKVETI 341

Query: 73  TESIGCVMTGMTADSRSQVQRARYEAANWKYKYGYEIPVDMLCKRIADISQVYTQNAEMR 132
           T++IG V +GM  D R   +RAR  A  +K  Y  +IP   L +R+A + Q +TQ+  +R
Sbjct: 342 TKNIGIVYSGMGPDYRVLCRRARKLAEQYKRVYNEQIPTAQLVQRVAAVMQEFTQSGGVR 521

Query: 133 PLGCCMILIGIDE-EQGPQVYKCDPAGYYCGFKATAAGVKQTESTSFLEKKVKKKFDWTF 191
           P G  +++ G DE ++ P +Y+CDP+G Y  +KATA G       +FLEK+  +  +   
Sbjct: 522 PFGVSLLMAGWDEDDKKPFLYQCDPSGAYFAWKATAMGKNHINGKTFLEKRYSETLE--L 695

Query: 192 EQTVETAITCLSTVLSIDFKPSEIEVGVVTVENPKFRILTEAEIDAHLVALA 243
           E  V TAI  L            IE+G+    +  FR L  +EI  +L +++
Sbjct: 696 EDAVHTAILALKESFEGQMTEDNIEIGICN--SSGFRRLEPSEIKDYLASVS 845
>02448
          Length = 1302

 Score =  132 bits (333), Expect = 1e-31,   Method: Compositional matrix adjust.
 Identities = 72/209 (34%), Positives = 113/209 (54%)
 Frame = +2

Query: 9   FDRHITIFSPEGRLYQVEYAFKAINQGGLTSVAVRGKDCAVIVTQKKVPDKLLDSSTVTH 68
           +DR IT+FSP+G L+QVEYA +A+ +G  T+V VRG +  V+  +KK   KL +  TV  
Sbjct: 263 YDRAITVFSPDGHLFQVEYAQEAVKKGS-TAVGVRGNNLVVLGVEKKAVAKLQEERTVRK 439

Query: 69  LFKITESIGCVMTGMTADSRSQVQRARYEAANWKYKYGYEIPVDMLCKRIADISQVYTQN 128
           +  + E +     G+TAD+R  + RAR E  + K      + V+ + + IA + Q YTQ+
Sbjct: 440 IALLDEHVALAFAGLTADARILINRARIECQSHKLTVEDPVTVEYITRHIAQLKQKYTQS 619

Query: 129 AEMRPLGCCMILIGIDEEQGPQVYKCDPAGYYCGFKATAAGVKQTESTSFLEKKVKKKFD 188
              RP G   ++IG D +  P +Y+ DP+G Y  +KA   G        FLEK    +  
Sbjct: 620 NGRRPFGLSSLIIGFDYDGSPHLYQTDPSGTYHEWKANTIGRNAKTVREFLEKHYTDEVA 799

Query: 189 WTFEQTVETAITCLSTVLSIDFKPSEIEV 217
            + ++T++ A+  L  V+    K  E+ V
Sbjct: 800 ASDKETIKLALKALLEVVQSGAKNMEVAV 886
>00789
          Length = 1584

 Score =  132 bits (332), Expect = 1e-31,   Method: Compositional matrix adjust.
 Identities = 73/237 (30%), Positives = 130/237 (54%), Gaps = 4/237 (1%)
 Frame = +1

Query: 9   FDRHITIFSPEGRLYQVEYAFKAINQGGLTSVAVRGKDCAVIVTQKKVPDKLLDSSTVTH 68
           +D   TIFSPEGRLYQVEYA +AI   G T + +  KD  V+  +++  +KLLD  + + 
Sbjct: 34  YDSRTTIFSPEGRLYQVEYAMEAIGHAG-TCLGILAKDGIVLAAERRNTNKLLDEVSYSE 210

Query: 69  -LFKITESIGCVMTGMTADSRSQVQRARYEAANWKYKYGYEIPVDMLCKRIADISQVYTQ 127
            ++++++ + C + G+T+D+       R  A  +  +Y   IP + +   + DI Q YTQ
Sbjct: 211 KIYRLSDDMACSVAGITSDANVLTNELRLIAQRYLLQYQEPIPCEQVVATLCDIKQAYTQ 390

Query: 128 NAEMRPLGCCMILIGIDEEQGPQVYKCDPAGYYCGFKATAAGVKQTESTSFLEKKVKKKF 187
               RP G  ++ +G D+  G Q+Y+ DP+G Y G+KAT  G     + S L+++ K+  
Sbjct: 391 FGGKRPFGVSILYMGWDKHYGFQLYQSDPSGNYGGWKATCIGNNSANAVSLLKQEYKED- 567

Query: 188 DWTFEQTVETAITCLSTVLSI-DFKPSEIEVGVVTVENPK--FRILTEAEIDAHLVA 241
           + + ++ +  +I  L   L +    P ++E+  +T ++ K    IL + ++D  + A
Sbjct: 568 ESSLDEALALSIKVLGKTLDLTKLTPDKVEMATLTRKDGKTVMTILPDNQVDTLIKA 738
>24591
          Length = 1801

 Score =  131 bits (330), Expect = 2e-31,   Method: Compositional matrix adjust.
 Identities = 72/209 (34%), Positives = 113/209 (54%)
 Frame = +1

Query: 9   FDRHITIFSPEGRLYQVEYAFKAINQGGLTSVAVRGKDCAVIVTQKKVPDKLLDSSTVTH 68
           +DR IT+FSP+G L+QVEYA +A+ +G  T+V VRG +  V+  +KK   KL +  TV  
Sbjct: 40  YDRAITVFSPDGHLFQVEYAQEAVKKGS-TAVGVRGDNLVVLGVEKKAVAKLQEERTVRK 216

Query: 69  LFKITESIGCVMTGMTADSRSQVQRARYEAANWKYKYGYEIPVDMLCKRIADISQVYTQN 128
           +  + E +     G+TAD+R  + RAR E  + K      + V+ + + IA + Q YTQ+
Sbjct: 217 IALLDEHVALAFAGLTADARILINRARIECQSHKLTVEDPVTVEYITRHIAQLKQKYTQS 396

Query: 129 AEMRPLGCCMILIGIDEEQGPQVYKCDPAGYYCGFKATAAGVKQTESTSFLEKKVKKKFD 188
              RP G   ++IG D +  P +Y+ DP+G Y  +KA   G        FLEK    +  
Sbjct: 397 NGRRPFGLSSLIIGFDYDGTPHLYQTDPSGTYHEWKANTIGRNAKTVREFLEKHYTDEVA 576

Query: 189 WTFEQTVETAITCLSTVLSIDFKPSEIEV 217
            + ++T++ A+  L  V+    K  E+ V
Sbjct: 577 ASDKETIKLALKALLEVVQSGAKNMEVAV 663
>17033
          Length = 2217

 Score =  127 bits (319), Expect = 4e-30,   Method: Compositional matrix adjust.
 Identities = 69/190 (36%), Positives = 108/190 (56%), Gaps = 1/190 (0%)
 Frame = -3

Query: 8    GFDRHITIFSPEGRLYQVEYAFKAINQGGLTSVAVRGKDCAVIVTQKKVPDKLLDSSTVT 67
            G+D   + FSP+GR++QVEYA KA+   G T++ +RGKD  V+  +K V  KL +     
Sbjct: 2152 GYDLSASHFSPDGRVFQVEYAQKAVENSG-TAIGIRGKDGVVMGVEKLVTSKLYEQGANK 1976

Query: 68   HLFKITESIGCVMTGMTADSRSQVQRARYEAANWKYKYGYEIPVDMLCKRIADISQVYTQ 127
             LF I   IG  + G+ AD+R  ++RA+ E++N+++ YG  +P+  L  R+A     YT 
Sbjct: 1975 RLFNIDRHIGGAVAGLLADARQLMERAKEESSNYRFNYGSPVPLKYLTDRVAGYVHAYTL 1796

Query: 128  NAEMRPLGCCMILIGIDEEQGPQVYKCDPAGYYCGFKATAAG-VKQTESTSFLEKKVKKK 186
            ++ +RP G  MI+   D   GPQ++  +P+G   G+   A G  KQT  T   + K+K  
Sbjct: 1795 HSAVRPFGTSMIVASYD-AVGPQMFLVEPSGVSWGYYGCAIGKAKQTAKTEIEKLKMK-- 1625

Query: 187  FDWTFEQTVE 196
             D T +  V+
Sbjct: 1624 -DLTMQDLVK 1598
>20771
          Length = 674

 Score =  118 bits (296), Expect = 2e-27,   Method: Compositional matrix adjust.
 Identities = 55/182 (30%), Positives = 106/182 (58%), Gaps = 5/182 (2%)
 Frame = +2

Query: 9   FDRHITIFSPEGRLYQVEYAFKAINQGGLTSVAVRGKDCAVIVTQKKVPDKLLDSSTVTH 68
           +DR +  FSPEGRL+QVEYA +AI  G  T++ ++  +  V+  +K+V   L++ +++  
Sbjct: 101 YDRGVNTFSPEGRLFQVEYAIEAIKLGS-TAIGIQTNEGVVLAVEKRVTSSLIEPTSIEK 277

Query: 69  LFKITESIGCVMTGMTADSRSQVQRARYEAANWKYKYGYEIPVDMLCKRIADISQVYTQN 128
           + ++ + IGC M+G+ ADSR+ + RAR EA N  + Y   + V+ + + +++++  +  +
Sbjct: 278 IMEVDKHIGCAMSGLIADSRTLIDRARVEAQNHWFTYNENMSVESVTQAVSNLALAFGDD 457

Query: 129 -----AEMRPLGCCMILIGIDEEQGPQVYKCDPAGYYCGFKATAAGVKQTESTSFLEKKV 183
                A  RP G  +++ G+D   GP+++  DP+G +  + A A G     +   L+++ 
Sbjct: 458 DPDPGAMSRPFGVALLIAGVD-SNGPRLFHMDPSGTFIQYDAKAIGSGSEGAQQALQEQY 634

Query: 184 KK 185
            K
Sbjct: 635 HK 640
>11023
          Length = 1057

 Score = 97.1 bits (240), Expect = 6e-21,   Method: Compositional matrix adjust.
 Identities = 44/66 (66%), Positives = 55/66 (83%)
 Frame = -1

Query: 181 KKVKKKFDWTFEQTVETAITCLSTVLSIDFKPSEIEVGVVTVENPKFRILTEAEIDAHLV 240
           K++KKK D+T+ +  E AITCLSTVLS DFK SE+EVG+VT +NP FRILTEA+ID HL 
Sbjct: 868 KEIKKKQDFTYNEAAEIAITCLSTVLSADFKASEVEVGIVTKDNPNFRILTEADIDVHLT 689

Query: 241 ALAERD 246
           A+AE+D
Sbjct: 688 AIAEKD 671

 Score = 79.0 bits (193), Expect = 2e-15,   Method: Compositional matrix adjust.
 Identities = 37/65 (56%), Positives = 46/65 (70%), Gaps = 1/65 (1%)
 Frame = -2

Query: 138 MILIGIDEEQGPQVYKCDPAGYYCGFKATAAGVKQTESTSFLEKKVKK-KFDWTFEQTVE 196
           MILIG D+E+GP+VYK DPAGYYCGFKAT+AG KQ E+  FLEK+ ++ K   T  Q   
Sbjct: 996 MILIGYDDEKGPEVYKTDPAGYYCGFKATSAGSKQLEANGFLEKRSRRSKTSPTMRQQRS 817

Query: 197 TAITC 201
            +  C
Sbjct: 816 LSPVC 802
>19133
          Length = 692

 Score = 58.2 bits (139), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 40/167 (23%), Positives = 78/167 (46%), Gaps = 7/167 (4%)
 Frame = +1

Query: 83  MTADSRSQVQRARYEAANWKYKYGYEIPVDMLCKRIADISQVYTQNAEMRPLGCCMILIG 142
           +TAD+R      + E  + ++ Y   +PV  L   I +  Q+ T     RP G  +++ G
Sbjct: 1   LTADARLLCNFMQTECLDSRWAYQQPLPVSRLVSAIGNKLQIPTHRYGRRPFGVGLLIAG 180

Query: 143 IDEEQGPQVYKCDPAGYYCGFKATAAGVKQTESTSFLEKKVKKKFDWTFEQTVETAITCL 202
            D   GP +Y+  P+  Y   KA A G +   + ++LE+ + +    + ++ V+  +  L
Sbjct: 181 YDWS-GPHIYQTCPSANYYDCKAMAIGARSQSARTYLERHLDQFPQCSLDELVKHGLRAL 357

Query: 203 STVLSIDFKPSEI-------EVGVVTVENPKFRILTEAEIDAHLVAL 242
              L     PSE+        +G+V  ++ KF+I  +  + ++L  +
Sbjct: 358 RDTL-----PSEVTLSTKNCSLGIVD-KDMKFKIYDDENVASYLALI 480
>28971
          Length = 437

 Score = 52.0 bits (123), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 24/64 (37%), Positives = 38/64 (59%)
 Frame = +1

Query: 123 QVYTQNAEMRPLGCCMILIGIDEEQGPQVYKCDPAGYYCGFKATAAGVKQTESTSFLEKK 182
           Q YTQ+  +RP G  +++ G D E+ P +Y+ DP+G Y  +KATA G       +FL K 
Sbjct: 4   QEYTQSGGVRPFGVSLLICGWDNER-PYLYQSDPSGAYFAWKATAMGKNAVNGKNFLGKA 180

Query: 183 VKKK 186
           + ++
Sbjct: 181 L*RR 192
>15509
          Length = 344

 Score = 28.5 bits (62), Expect = 2.9,   Method: Compositional matrix adjust.
 Identities = 18/58 (31%), Positives = 27/58 (46%)
 Frame = +1

Query: 137 CMILIGIDEEQGPQVYKCDPAGYYCGFKATAAGVKQTESTSFLEKKVKKKFDWTFEQT 194
           CM  + +D  +   +Y+ +    Y GF+A    V+   ST  LE    +  D TF QT
Sbjct: 100 CMFWLKLDSVRMYAIYRGESCPAYAGFQARTNYVRAVSSTEPLELASFRHKD-TFLQT 270
>33143
          Length = 1469

 Score = 28.1 bits (61), Expect = 3.9,   Method: Compositional matrix adjust.
 Identities = 12/26 (46%), Positives = 17/26 (65%)
 Frame = +2

Query: 213 SEIEVGVVTVENPKFRILTEAEIDAH 238
           ++I   V+ + NP+  ILTEAEI  H
Sbjct: 947 TQIVSAVMNLPNPRLSILTEAEI*TH 1024
>12467
          Length = 468

 Score = 26.6 bits (57), Expect = 9.3,   Method: Compositional matrix adjust.
 Identities = 10/28 (35%), Positives = 17/28 (60%)
 Frame = -3

Query: 23  YQVEYAFKAINQGGLTSVAVRGKDCAVI 50
           Y   Y   + N  G+TSV +RG++C+ +
Sbjct: 442 YTPTYIIVSTNTQGVTSVRMRGRECSAV 359
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|68226731|ref|NP_032968.2| aminopeptidase puromycin
sensitive [Mus musculus]
         (920 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

20340                                                                 326   3e-89
26751                                                                 231   1e-60
33589                                                                 226   4e-59
29830                                                                 111   5e-40
25866                                                                 122   4e-28
12507                                                                 119   7e-27
22981                                                                  54   2e-07
17972                                                                  47   3e-05
13839                                                                  37   0.044
00139                                                                  33   0.36 
36866                                                                  30   3.7  
>20340
          Length = 617

 Score =  326 bits (835), Expect = 3e-89,   Method: Compositional matrix adjust.
 Identities = 148/205 (72%), Positives = 172/205 (83%)
 Frame = -1

Query: 303 LPKIDLIAIADFAAGAMENWGLVTYRETALLIDPKNSCSSSRQWVALVVGHELAHQWFGN 362
           LPK+DL+A  DF  GAMENWGLV YRETALL+D + S S  ++++AL++GHELAH WFGN
Sbjct: 614 LPKLDLVAAPDFPIGAMENWGLVIYRETALLVDTETS-SFLKEYIALIIGHELAHNWFGN 438

Query: 363 LVTMEWWTHLWLNEGFASWIEYLCVDHCFPEYDIWTQFVSADYTRAQELDALDNSHPIEV 422
           LVTM WWTHLWL EGFASWIEYLCVDHCFPEYDIWTQFVS D  RA +LDAL+NSHPIE+
Sbjct: 437 LVTMNWWTHLWLKEGFASWIEYLCVDHCFPEYDIWTQFVSNDLGRALKLDALNNSHPIEI 258

Query: 423 SVGHPSEVDEIFDAISYSKGASVIRMLHDYIGDKDFKKGMNMYLTKFQQKNAATEDLWES 482
            VG+PSEVDEIFDAISYSKGAS+I MLHDYIGD DF+KGM  YL + Q  +A TEDLW++
Sbjct: 257 EVGNPSEVDEIFDAISYSKGASIINMLHDYIGDADFRKGMTAYLQRHQYSSACTEDLWKA 78

Query: 483 LESASGKPIAAVMNTWTKQMGFPLI 507
           LE ASGKP+  +M TWT Q GFP++
Sbjct: 77  LEEASGKPVGTMMTTWTSQKGFPVL 3
>26751
          Length = 491

 Score =  231 bits (588), Expect = 1e-60,   Method: Compositional matrix adjust.
 Identities = 109/163 (66%), Positives = 129/163 (79%), Gaps = 1/163 (0%)
 Frame = +3

Query: 203 ISLVVPKDRVALSNMNVIDRKPYPDDENLVEVKFARTPVMSTYLVAFVVGEYDFVETRSK 262
           ++LV PKDRV LSNM V+       D +   +KF RTP+MSTYL+AFVVGE+D+VE +  
Sbjct: 3   VTLVGPKDRVILSNMPVVSETSLESDSSQKVMKFERTPIMSTYLLAFVVGEFDYVEAKDA 182

Query: 263 DGVCVRVYTPVGKAEQGKFALEVAAKTLPFYKDYFNVPYPLPKIDLIAIADFAAGAMENW 322
           DGV +RVYTP+GK EQG+FALEV+ KTLPFYKDYF + YPLPK+DLIAIADF+AGAMENW
Sbjct: 183 DGVLIRVYTPLGKKEQGQFALEVSVKTLPFYKDYFGIAYPLPKMDLIAIADFSAGAMENW 362

Query: 323 GLVTYRETALLIDPKNSCSSSRQWVALVVGHELA-HQWFGNLV 364
           GLVTYRETALL+DPKN+ +  R WVALVVG       WFGNLV
Sbjct: 363 GLVTYRETALLVDPKNTSTRVRLWVALVVGRRAGVTTWFGNLV 491
>33589
          Length = 686

 Score =  226 bits (575), Expect = 4e-59,   Method: Compositional matrix adjust.
 Identities = 104/184 (56%), Positives = 132/184 (71%)
 Frame = +2

Query: 392 PEYDIWTQFVSADYTRAQELDALDNSHPIEVSVGHPSEVDEIFDAISYSKGASVIRMLHD 451
           PE+D+WTQF++ D  RA ELDAL NSHPIEV VG P EVDEIFDAISYSKGASVIRMLHD
Sbjct: 2   PEFDVWTQFINTDLGRALELDALHNSHPIEVEVGRPDEVDEIFDAISYSKGASVIRMLHD 181

Query: 452 YIGDKDFKKGMNMYLTKFQQKNAATEDLWESLESASGKPIAAVMNTWTKQMGFPLIYVEA 511
           YIGD DF+KGMN+YLT+ +  N  TEDLW++LE ASGKP+  +M TWT Q GFP++ V  
Sbjct: 182 YIGDADFRKGMNLYLTRHKFSNTLTEDLWKALEEASGKPVGTMMATWTSQKGFPVVKVSQ 361

Query: 512 EQVEDDRVLKLSQKKFCASGPYGGEDCPQWMVPITISTSEDPNQAKLKILMDKPEMSVVL 571
           +Q    R L + Q+KFCA G   GE   +W+VP+ +ST   P++     LM+    ++ L
Sbjct: 362 KQEGTTRTLTVEQEKFCADGKQQGEGY-KWLVPVCVSTGSSPDKPVATTLMENTSTTITL 538

Query: 572 KNVK 575
            ++K
Sbjct: 539 NDIK 550

 Score = 60.8 bits (146), Expect = 2e-09,   Method: Composition-based stats.
 Identities = 28/49 (57%), Positives = 35/49 (71%)
 Frame = +3

Query: 565 PEMSVVLKNVKPDQWVKLNLGTVGFYRTQYSSAMLESLLPGIRDLSLPP 613
           P +S +LK    D+WVK+N G VG YR QYSS ML+ L+P I+D SLPP
Sbjct: 528 PSLSTILK---ADEWVKVNTGCVGVYRVQYSSDMLDQLIPAIKDRSLPP 665
>29830
          Length = 1148

 Score =  111 bits (278), Expect(2) = 5e-40,   Method: Compositional matrix adjust.
 Identities = 63/190 (33%), Positives = 105/190 (55%), Gaps = 11/190 (5%)
 Frame = -1

Query: 376 EGFASWIEYLCVDHCFPEYDIWTQFVSADYTRAQELDALDNSHPIEVSVGHPSEVDEIFD 435
           E FAS+ ++  V    PE+    + V+         DAL +SHP+   V   +EV  IFD
Sbjct: 605 EAFASFWDFHSVGALHPEWRETEEAVANGLHSVMTSDALASSHPMTADVMTRAEVSSIFD 426

Query: 436 AISYSKGASVIRMLHDYIGDKDFKKGMNMYLTKFQQKNAATEDLWESLESASGKPIAAVM 495
           A++Y+KG+ +IRM+H  +G+  F + +N YL + Q  N    DLW++L++ +   +  +M
Sbjct: 425 AVTYTKGSFIIRMMHFIMGEDKFIEALNNYLHQHQXDNVEHSDLWQALDNVADVNMTLIM 246

Query: 496 NTWTKQMGFPLIYVEAEQVEDDRVLKLSQKKFCASG-----------PYGGEDCPQWMVP 544
           + W  QMG+P+  V A ++ +  V +L+Q++F               PYG     QW +P
Sbjct: 245 DPWVTQMGYPV--VMASRLGNGGV-RLTQQRFLLGSEDTTDDRYKDPPYG----YQWEIP 87

Query: 545 ITISTSEDPN 554
           IT+++S+DPN
Sbjct: 86  ITVASSDDPN 57

 Score = 72.4 bits (176), Expect(2) = 5e-40,   Method: Compositional matrix adjust.
 Identities = 33/53 (62%), Positives = 38/53 (71%)
 Frame = -3

Query: 313 DFAAGAMENWGLVTYRETALLIDPKNSCSSSRQWVALVVGHELAHQWFGNLVT 365
           DF AGAMENWGL+TYRET LL  P  +  +   W A V+ HE+AH WFGNLVT
Sbjct: 792 DFNAGAMENWGLITYRET-LLYKPGVTSKTDEMWAAEVIAHEIAHMWFGNLVT 637
>25866
          Length = 422

 Score =  122 bits (307), Expect = 4e-28,   Method: Compositional matrix adjust.
 Identities = 59/140 (42%), Positives = 85/140 (60%)
 Frame = +3

Query: 630 GIISTVEVLKVMEAFVNEPNYTVWSDLSCNLGILSTLLSHTDFYEEIQEFVKDVFSPIGE 689
           G  S V+VLKV EA+VNE +YTVW+DLS +L  ++ LL +TD Y + + + + +FS I  
Sbjct: 3   GCCSAVDVLKVTEAYVNEVDYTVWTDLSGSLSSVALLLQYTDSYPQYKAYARKLFSTIAA 182

Query: 690 RLGWDPKPGEXXXXXXXXXXXXXXXXXXXXXXXXEEARRRFKEHVEGKQILSADLRSPVY 749
            +GWDPKP +                         EA++RF++HV G++ L ADLR PVY
Sbjct: 183 SVGWDPKPDDGQLTPMLRDLVLTRMGRYNDVATVAEAKKRFQQHVSGEKTLPADLRGPVY 362

Query: 750 LTVLKHGDGATLDIMLKLHK 769
           +TVL +GD A  D ML+L++
Sbjct: 363 ITVLTNGDAAVFDQMLELYE 422
>12507
          Length = 829

 Score =  119 bits (297), Expect = 7e-27,   Method: Compositional matrix adjust.
 Identities = 50/91 (54%), Positives = 71/91 (78%)
 Frame = -1

Query: 820 GSKHGRKAAWKFIKDNWEELHNRYQGGFLISRLIKLSVEGFAVDKMAGEVKAFFESHPAP 879
           GS  GR  AW+F+K+NW++LH RY+GGFL+SRLIK S E F  ++ A EV+ FF+++P  
Sbjct: 823 GSVKGRDMAWEFVKENWKKLHERYEGGFLLSRLIKSSTENFVTEEKAKEVQEFFKTNPVA 644

Query: 880 SAERTIQQCCENILLNAAWLKRDADSIHQYL 910
           +AERT++Q CENI LNAAWL+R++ ++  YL
Sbjct: 643 AAERTVEQSCENIRLNAAWLERESVAVTTYL 551
>22981
          Length = 564

 Score = 54.3 bits (129), Expect = 2e-07,   Method: Composition-based stats.
 Identities = 38/132 (28%), Positives = 60/132 (45%), Gaps = 4/132 (3%)
 Frame = +2

Query: 786 ATLSPELIQKVLTFALS-EEVRPQDTVSVIGGVAGGSKHGRKAAWKFIKDNWEELHNRYQ 844
           A L+P      L  +L+  E+R QD ++VIG + G +  GR  AW F + +W+ +   + 
Sbjct: 86  ALLTPGFSAGNLELSLNPAEIRKQDALNVIGSIXGNTI-GRALAWDFFRGHWDTIRAEHG 262

Query: 845 GGFL-ISRLIKLSVEGFAVDKMAGEVKAFFESHP-APSAERTIQQCCENILLNAAWLKRD 902
             F   + LI      F       +++ F   HP   S  R  QQ  E    N AW+ ++
Sbjct: 263 ASFFSFTSLISSVTYSFNTQFELKQLQDFIRDHPDQGSGRRAFQQAVEKARSNIAWMDKN 442

Query: 903 ADSIHQYL-LQR 913
              +  +L LQR
Sbjct: 443 YAILTDWLRLQR 478
>17972
          Length = 688

 Score = 47.4 bits (111), Expect = 3e-05,   Method: Composition-based stats.
 Identities = 33/150 (22%), Positives = 61/150 (40%), Gaps = 2/150 (1%)
 Frame = +3

Query: 769 KQADMQEEKNRIERVLGATLSPELIQKVLTFALSEEVRPQDTVSVIGGVAGGSKHGRKAA 828
           K   +  E+  ++   G      LI++V    +S+E+RPQD  SV   +   +       
Sbjct: 42  KTTKVATEETLLQNSFGCVKHHTLIERVFNLIVSDEIRPQDKSSVFNTLYTENNENVSPV 221

Query: 829 WKFIKDNWEELHNRYQGGFLISRLIKLSVEGFAVDKMAGEVKAFFESHPAP--SAERTIQ 886
           +  +   ++EL     G   ++ +I      F  +    ++K F   + A   SA  T++
Sbjct: 222 FALVTKRYDELATALNGYGAVATIISNIASRFTEESQYEDLKKFNTENKAKFGSAASTLE 401

Query: 887 QCCENILLNAAWLKRDADSIHQYLLQRKTS 916
              + +  N AW +    +   YL QR  S
Sbjct: 402 AAEKTVXENLAWAETKLGTFRTYLAQRNGS 491
>13839
          Length = 1440

 Score = 36.6 bits (83), Expect = 0.044,   Method: Compositional matrix adjust.
 Identities = 25/96 (26%), Positives = 49/96 (51%), Gaps = 7/96 (7%)
 Frame = -3

Query: 540  QWMVPITISTSEDPNQAK----LKILMDKPEMSVVLKNV-KPDQWVKLNLGTVGFYRTQY 594
            QW +P+  +TS+ P+  K    +  L    ++ +    V + D W+ +N+ T  + R  Y
Sbjct: 1183 QWEIPVIFATSDKPDMHKSRDDIHWLSKNSDLFIADSQVNETDAWILVNINTTTYCRVLY 1004

Query: 595  SSAMLESLLPGI-RDLS-LPPVDRLGLQNDLFSLAR 628
             +    +L+  + RD S L  ++R  + ND ++LA+
Sbjct: 1003 DAHTWRALIGQLNRDPSVLTAINRGQIINDAWNLAK 896
>00139
          Length = 1653

 Score = 33.5 bits (75), Expect = 0.36,   Method: Compositional matrix adjust.
 Identities = 38/176 (21%), Positives = 71/176 (40%), Gaps = 4/176 (2%)
 Frame = +2

Query: 445 VIRMLHDYIGDKDFKKGMNMYLTKFQQKNAATEDLWESLESASGKPIAAVMNTWTKQMGF 504
            + +LH  +  +DF K M+    +++Q+   T+D+ +  E    +PI+ +     ++   
Sbjct: 107 TLAILHSKVAFEDFNKHMSKMYHQYEQQR--TDDIVDPSERQQ-RPISTISGIGAQEKPL 277

Query: 505 PLIYVEAEQVEDDRVLKL----SQKKFCASGPYGGEDCPQWMVPITISTSEDPNQAKLKI 560
           P   V+  ++ DD    +     +K   A     G++  +     T ST +    +K + 
Sbjct: 278 PKSTVQISEITDDEAAAMQNADGEKPGQAQEKKEGDEKSETAT--TESTDQGSTASKTES 451

Query: 561 LMDKPEMSVVLKNVKPDQWVKLNLGTVGFYRTQYSSAMLESLLPGIRDLSLPPVDR 616
             D+PE S    + K D   +   G VG    +   A      P   +  LPP  R
Sbjct: 452 TNDEPETSAPEADNKEDADKEEERGAVGGAEIEPPGAS----PPEKSNTVLPPSTR 607
>36866
          Length = 688

 Score = 30.4 bits (67), Expect = 3.7,   Method: Composition-based stats.
 Identities = 17/36 (47%), Positives = 21/36 (58%)
 Frame = +3

Query: 46  MPEKRPFERLPAEVSPINYSLCLKPDLLDFTFEGKL 81
           +P+KRP    P  VS I   LC+ P +L F F GKL
Sbjct: 300 VPDKRP----PRIVSDIFTGLCITPLVLLFVFWGKL 395
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|224967109|ref|NP_081628.3| golgi reassembly stacking
protein 2 [Mus musculus]
         (451 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

15120                                                                 322   2e-88
21326                                                                 172   3e-43
>15120
          Length = 928

 Score =  322 bits (824), Expect = 2e-88,   Method: Compositional matrix adjust.
 Identities = 151/234 (64%), Positives = 175/234 (74%)
 Frame = -3

Query: 1   MGSSQSVEIPGGGTEGYHVLRVQENSPGHRAGLEPFFDFIVSINGSRXXXXXXXXXXXXX 60
           MG S S EIPGGGTEGYHVLRVQ++SPG  AGLE FFDFIV+I  +R             
Sbjct: 872 MGGSASTEIPGGGTEGYHVLRVQDSSPGQAAGLEAFFDFIVAIGNTRLNKDNETLKELLK 693

Query: 61  XXVEKPVKMLIYSSKTLELREASVTPSNLWGGQGLLGVSIRFCSFDGANENVWHVLEVES 120
             +EKPVKM +YSSKT  +R+ ++ PS+ WGGQGLLGVSIRFCSF+GANENVWH+LEV+ 
Sbjct: 692 SNIEKPVKMTVYSSKTQGVRDVTIMPSHNWGGQGLLGVSIRFCSFEGANENVWHILEVQP 513

Query: 121 NSPAALAGLRPHSDYIIGADTVMNESEDLFSLIETHEAKPLKLYVYNTDTDNCREVIITP 180
           NSPA LAG++  +DY+IGAD+V++ESEDLFSLIE+HE KPLKLYVYN DTD+CREV ITP
Sbjct: 512 NSPADLAGMKSDTDYVIGADSVLHESEDLFSLIESHEGKPLKLYVYNADTDSCREVTITP 333

Query: 181 NSAWGGEGSLGCGIGYGYLHRIPTRPFEEGKKISLPGQMTGTPITPLKDGFTEV 234
           N AWGGEGSLGC IGYGYLHRIP R F           M   P     DGF+EV
Sbjct: 332 NGAWGGEGSLGCNIGYGYLHRIPKRQFPSDGTKQAANLMIPAPSQTKVDGFSEV 171
>21326
          Length = 388

 Score =  172 bits (435), Expect = 3e-43,   Method: Composition-based stats.
 Identities = 75/111 (67%), Positives = 95/111 (85%)
 Frame = -3

Query: 63  VEKPVKMLIYSSKTLELREASVTPSNLWGGQGLLGVSIRFCSFDGANENVWHVLEVESNS 122
           V+KPV++ +YSSKT  +RE ++TPS  WGGQGLLGVSIRFCSF+GANE+VWH+LEV  NS
Sbjct: 335 VDKPVRITVYSSKTQTVRELTLTPSTSWGGQGLLGVSIRFCSFEGANESVWHILEVHPNS 156

Query: 123 PAALAGLRPHSDYIIGADTVMNESEDLFSLIETHEAKPLKLYVYNTDTDNC 173
           PA LAGLR +SDY+IGAD + +E++DLF+LIE+HE +PLK+YVYN D D C
Sbjct: 155 PAELAGLRAYSDYVIGADAIRHENDDLFTLIESHEQQPLKMYVYNLDDDAC 3

 Score = 45.8 bits (107), Expect = 3e-05,   Method: Composition-based stats.
 Identities = 19/57 (33%), Positives = 37/57 (64%), Gaps = 1/57 (1%)
 Frame = -3

Query: 141 TVMNESEDLF-SLIETHEAKPLKLYVYNTDTDNCREVIITPNSAWGGEGSLGCGIGY 196
           T +++  D+   L+  +  KP+++ VY++ T   RE+ +TP+++WGG+G LG  I +
Sbjct: 386 TRLDQDNDMLKELLRQNVDKPVRITVYSSKTQTVRELTLTPSTSWGGQGLLGVSIRF 216

 Score = 32.3 bits (72), Expect = 0.38,   Method: Composition-based stats.
 Identities = 16/63 (25%), Positives = 28/63 (44%)
 Frame = -3

Query: 11  GGGTEGYHVLRVQENSPGHRAGLEPFFDFIVSINGSRXXXXXXXXXXXXXXXVEKPVKML 70
           G     +H+L V  NSP   AGL  + D+++  +  R                ++P+KM 
Sbjct: 203 GANESVWHILEVHPNSPAELAGLRAYSDYVIGADAIRHENDDLFTLIESHE--QQPLKMY 30

Query: 71  IYS 73
           +Y+
Sbjct: 29  VYN 21
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|171543837|ref|NP_032080.2| protein-tyrosine kinase
fyn isoform b [Mus musculus]
         (534 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

21808                                                                 318   4e-88
06405                                                                 298   5e-81
11780                                                                 192   1e-68
09007                                                                 156   2e-38
04852                                                                 150   1e-36
17300                                                                 123   3e-33
20640                                                                 125   6e-29
07291                                                                 122   3e-28
14116                                                                 121   7e-28
07940                                                                 102   3e-22
08294                                                                 102   4e-22
18996                                                                  98   8e-21
22005                                                                  84   1e-20
01718                                                                  96   3e-20
17637                                                                  92   4e-19
13592                                                                  92   8e-19
14477                                                                  89   5e-18
13305                                                                  81   8e-16
19301                                                                  79   4e-15
01756                                                                  77   1e-14
00715                                                                  77   3e-14
12721                                                                  71   9e-13
17253                                                                  70   2e-12
01060                                                                  70   3e-12
01707                                                                  68   1e-11
18921                                                                  67   1e-11
29581                                                                  66   3e-11
00300                                                                  63   3e-10
25550                                                                  63   3e-10
18484                                                                  63   3e-10
14420                                                                  63   3e-10
14126                                                                  61   9e-10
27546                                                                  61   1e-09
04591                                                                  60   2e-09
01966                                                                  60   3e-09
00392                                                                  59   5e-09
11228                                                                  58   9e-09
31885                                                                  57   1e-08
07836                                                                  57   2e-08
13066                                                                  57   3e-08
09606                                                                  56   4e-08
03240                                                                  55   7e-08
12672                                                                  54   2e-07
13212                                                                  53   3e-07
04138                                                                  52   4e-07
29243                                                                  52   7e-07
21079                                                                  51   9e-07
12324                                                                  49   5e-06
19094                                                                  49   7e-06
15910                                                                  48   1e-05
30755                                                                  47   1e-05
26560                                                                  46   3e-05
21210                                                                  46   5e-05
19761                                                                  45   8e-05
29687                                                                  45   8e-05
11185                                                                  44   1e-04
14257                                                                  44   1e-04
01106                                                                  44   2e-04
28638                                                                  42   5e-04
28095                                                                  42   7e-04
12786                                                                  41   0.001
05206                                                                  41   0.001
26711                                                                  41   0.001
37602                                                                  41   0.001
01494                                                                  40   0.002
18481                                                                  40   0.003
32000                                                                  40   0.003
16708                                                                  39   0.005
32264                                                                  39   0.006
35671                                                                  39   0.008
17286                                                                  38   0.012
16716                                                                  37   0.014
30740                                                                  37   0.017
00394                                                                  37   0.019
38046                                                                  37   0.023
27405                                                                  36   0.034
06462                                                                  36   0.036
31789                                                                  36   0.038
21433                                                                  36   0.045
01392                                                                  36   0.050
18881                                                                  35   0.054
07933                                                                  35   0.069
13664                                                                  35   0.073
29360                                                                  34   0.13 
02638                                                                  34   0.14 
37260                                                                  33   0.20 
18401                                                                  31   1.2  
13641                                                                  31   1.4  
36481                                                                  31   1.4  
23319                                                                  31   1.6  
27287                                                                  30   1.7  
29590                                                                  30   2.4  
18680                                                                  30   2.9  
27568                                                                  29   5.4  
27562                                                                  29   5.5  
18663                                                                  28   7.9  
15741                                                                  28   8.0  
>21808
          Length = 1011

 Score =  318 bits (815), Expect(2) = 4e-88,   Method: Compositional matrix adjust.
 Identities = 152/225 (67%), Positives = 180/225 (80%), Gaps = 1/225 (0%)
 Frame = +1

Query: 285 GTWNGNTKVAIKTLKPGTMSPESFLEEAQIMKKLKHDKLVQLYAVVSEE-PIYIVTEYMS 343
           G WN  T VAIKTLK GTM P+ FL EAQIMKKL+H KL+QLYAV +++ PI+I+TE M 
Sbjct: 4   GLWNNTTPVAIKTLKSGTMDPKDFLAEAQIMKKLRHPKLIQLYAVCTQDDPIFIITELMK 183

Query: 344 KGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKI 403
            GSLL+FL+ G+GR LKLP L+D+ AQ+A GMAY+E  NYIHRDL + NILV +    KI
Sbjct: 184 NGSLLEFLQ-GKGRVLKLPALIDIGAQIACGMAYLESQNYIHRDLAARNILVSDNNTVKI 360

Query: 404 ADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVP 463
           ADFGLAR+I+++EY AR GA+FPIKWTAPEAA Y RFTIKSDVWSFGILLTE VT GRVP
Sbjct: 361 ADFGLARVIKEDEYEARVGARFPIKWTAPEAANYNRFTIKSDVWSFGILLTETVTYGRVP 540

Query: 464 YPGMNNREVLEQVERGYRMPCPQDCPISLHELMIHCWKKDPEERP 508
           YPGM N EVL QVE GYRMPCP  CP  L+++M+ CW+K+  ERP
Sbjct: 541 YPGMTNAEVLHQVEHGYRMPCPPGCPKPLYDIMLECWRKEEMERP 675

 Score = 25.4 bits (54), Expect(2) = 4e-88,   Method: Compositional matrix adjust.
 Identities = 11/22 (50%), Positives = 14/22 (63%)
 Frame = +2

Query: 508 PTFEYLQGFLEDYFTATEPQYQ 529
           PTFE LQ  LE++FT     Y+
Sbjct: 674 PTFETLQWKLEEFFTMDSKDYR 739
>06405
          Length = 1965

 Score =  298 bits (762), Expect = 5e-81,   Method: Compositional matrix adjust.
 Identities = 159/350 (45%), Positives = 220/350 (62%), Gaps = 5/350 (1%)
 Frame = +1

Query: 177 ESETTKGAYSLSIRDWDDMKGDHVKHYKIRKLDNGGYYITTRAQFETLQQLVQHYSEKAD 236
           ESE++ G  S+S+R     +G  V HY+I + D+G  ++T   +F TL +LV H+S  AD
Sbjct: 1   ESESSPGQRSISVR----FEG-RVYHYRITE-DDGKVFVTQEHRFNTLAELVHHHSIHAD 162

Query: 237 GLCFNLTV-VSSSCTPQTSGLAK--DAWEVARDSLFLEKKLGQGCFAEVWLGTWNG-NTK 292
           GL   L         P   G++   D WE+ R  + ++ +LG G + +V+   W   N  
Sbjct: 163 GLVTTLLYPAPKRQKPTVFGVSPEPDRWEIERTEIAMKHRLGGGQYGDVYEAMWKRYNKI 342

Query: 293 VAIKTLKPGTMSPESFLEEAQIMKKLKHDKLVQLYAVVSEEP-IYIVTEYMSKGSLLDFL 351
           VA+KTLK  TM+   FLEEA IMK++KH  LVQL  V + EP  YIVTE+M  G+LLD+L
Sbjct: 343 VAVKTLKEDTMALNDFLEEAAIMKEMKHPNLVQLLGVCTREPPFYIVTEFMPHGNLLDYL 522

Query: 352 KDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARL 411
           +           L+ MA Q+A+GMAY+E  N+IHRDL + N LV +  + K+ADFGLARL
Sbjct: 523 RSSTREENGPTALMYMATQIASGMAYLETKNFIHRDLAARNCLVADSNMVKVADFGLARL 702

Query: 412 IEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNRE 471
           ++D+ YTA  GAKFPIKWTAPE   + RF+ +SD+W+FG+LL EL T G  PYPG+   E
Sbjct: 703 MKDDTYTAHIGAKFPIKWTAPEGLAFNRFSTRSDIWAFGVLLWELATYGMSPYPGVELTE 882

Query: 472 VLEQVERGYRMPCPQDCPISLHELMIHCWKKDPEERPTFEYLQGFLEDYF 521
           V   +ERGYRM  P   P  ++ LM+ CW+ DP++RPTF+ +   LE+ F
Sbjct: 883 VYHLLERGYRMERPPGTPADVYILMLKCWQWDPKDRPTFKEIHFLLENMF 1032
>11780
          Length = 1713

 Score =  192 bits (488), Expect(2) = 1e-68,   Method: Compositional matrix adjust.
 Identities = 124/341 (36%), Positives = 179/341 (52%), Gaps = 9/341 (2%)
 Frame = +3

Query: 103 FHKGEKFQILNSSEGDWWEARSLTTGETGYIPSNYVAP--VDSIQAEEWYFGKLGRKDAE 160
           F KG+   I  ++    W     + G  G IP+NYV P  V ++ A  W+ GK+ R+ AE
Sbjct: 111 FQKGDLLVIRRATSDRMWYKACDSNGREGMIPANYVQPRKVVTLHAMPWFHGKITRQQAE 290

Query: 161 RQLLSFGNPR--GTFLIRESETTKGAYSLSIRDWDDMKGDHVKHYKIRKLDNGGYYITTR 218
             L     PR  G FLIRES    G Y+L +          V+HY+I   +N    I   
Sbjct: 291 ELL----KPREDGLFLIRESSNYPGDYTLCV-----CHLGKVEHYRILYRENQ-LTIDEE 440

Query: 219 AQFETLQQLVQHYSEKADGLCFNLT--VVSSSCTPQTSGLAK---DAWEVARDSLFLEKK 273
             F  L +LV+HY   ADGLC  LT  V        T  L +     W +A   L + + 
Sbjct: 441 GFFRNLDELVKHYLADADGLCTQLTRPVTKQGGNFGTVSLQEFKSGGWVIAXQDLEIGEA 620

Query: 274 LGQGCFAEVWLGTWNGNTKVAIKTLKPGTMSPESFLEEAQIMKKLKHDKLVQLYAVVSEE 333
           +G+G F +V+ G + G   VAIK LK      +SFL+EA +M  L+HD LV+L  VV  E
Sbjct: 621 IGKGDFGDVYKGMYRGQP-VAIKQLKDKDRGEQSFLQEASVMTSLRHDNLVRLIGVVLGE 797

Query: 334 PIYIVTEYMSKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANI 393
            I++VTE+M KG+L+++L+      +   + ++ A    A M Y+E    +HRDL + N+
Sbjct: 798 TIFLVTEFMGKGNLVEYLRSRGRSVITKKDQINFATDTCAAMEYLESKRLVHRDLAARNV 977

Query: 394 LVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEA 434
           LV +    K++DFGLA+  + ++ +     KFPIKWTAPEA
Sbjct: 978 LVHDDGKAKVSDFGLAKFGDFSQTS----VKFPIKWTAPEA 1088

 Score = 86.7 bits (213), Expect(2) = 1e-68,   Method: Compositional matrix adjust.
 Identities = 41/86 (47%), Positives = 56/86 (65%)
 Frame = +1

Query: 439  RFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMIH 498
            +FT KSD+WSFGILL E+ + GRVPYP +   +V+  VERGYRM  P+ CP  ++ +M  
Sbjct: 1102 KFTSKSDMWSFGILLWEIYSFGRVPYPRIPLTDVVMHVERGYRMEAPEGCPPEIYSIMKQ 1281

Query: 499  CWKKDPEERPTFEYLQGFLEDYFTAT 524
             W+ DP ERPTF+ +   L +    T
Sbjct: 1282 AWELDPNERPTFKSVLARLNNQRAVT 1359
>09007
          Length = 1440

 Score =  156 bits (395), Expect = 2e-38,   Method: Compositional matrix adjust.
 Identities = 98/283 (34%), Positives = 152/283 (53%), Gaps = 15/283 (5%)
 Frame = -1

Query: 263 VARDSLFLEKKLGQGCFAEVWLGTWNGNT----KVAIKTLKPGTMSP--ESFLEEAQIMK 316
           +++D + L K LGQG F  V    W   +    +VA+K L    +    + FL+E  IM+
Sbjct: 888 ISKDCVALSKSLGQGHFGTVRQAIWTAESGEKVQVAVKCLSKDKIHKDGQEFLKETAIMQ 709

Query: 317 KLKHDKLVQLYAVVSEE--PIYIVTEYMSKGSLLDFLKDGEGRA-LKLPNLVDMAAQVAA 373
            L H+ +V++Y VV +    I +VTE     SLL+ +K+   R    +P L D + QV  
Sbjct: 708 MLDHENIVRVYGVVMDNGADIMLVTELAPMRSLLECVKEVSARVDFSVPRLCDFSQQVCD 529

Query: 374 GMAYIERMNYIHRDLRSANILVGNGLICKIADFGLA-RLIEDNEYTARQGA---KFPIKW 429
           GM+Y+E    +HRDL + NIL+ +    KI+D G++  L    EY   Q     +  + W
Sbjct: 528 GMSYLESKRLVHRDLAARNILLFSKSKVKISDVGVSGALGAGKEYYQSQQTIHLQNAVAW 349

Query: 430 TAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVE--RGYRMPCPQD 487
            APE+     F+  SDVW+FG+LL E  T G  P+ G+N ++++E V+  +  R+  P  
Sbjct: 348 CAPESFRNLCFSSASDVWAFGVLLWEFFTHGFQPWAGLNGQQIMEAVDAPQSQRLEQPDL 169

Query: 488 CPISLHELMIHCWKKDPEERPTFEYLQGFLEDYFTATEPQYQP 530
           CP   + +M+ CW+++P+ RPTF  L  FL      T PQ +P
Sbjct: 168 CPKEYYAVMLKCWEQEPQRRPTFSQL--FL------TLPQIRP 64
>04852
          Length = 1462

 Score =  150 bits (379), Expect = 1e-36,   Method: Compositional matrix adjust.
 Identities = 88/259 (33%), Positives = 137/259 (52%), Gaps = 31/259 (11%)
 Frame = +1

Query: 291 TKVAIKTLKPGTMSPE--SFLEEAQIMKKLK----HDKLVQLYAVVSEE-PIYIVTEYMS 343
           + VA+K L+    + E   F++E Q+MK +K    H  +V      ++  P++++ E+  
Sbjct: 22  STVAVKMLRDIVTAVEEQDFVQELQVMKAVKKMGSHINIVNFLGCCTQGGPLWVIVEFAK 201

Query: 344 KGSLLDFL---KDG--------------------EGRALKLPNLVDMAAQVAAGMAYIER 380
            G+L DFL   +DG                     G  ++  NL+  A Q+A GM ++  
Sbjct: 202 NGNLRDFLESCRDGINGYGKFVSPQDPGWYTKTPGGHVIRRKNLLSYAFQIARGMEFLAS 381

Query: 381 MNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRF 440
              IHRDL + N+LV    + KIADFGL+R    + Y  R G + P+KW APEA    R+
Sbjct: 382 RKCIHRDLAARNVLVTEEHVLKIADFGLSR--TGDYYKKRSGGRLPVKWMAPEALFDMRY 555

Query: 441 TIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQ-VERGYRMPCPQDCPISLHELMIHC 499
           T KSDVWSFG++L E+ + G +PY  + N E+  + ++  YRMP P+    +L+ +M  C
Sbjct: 556 TTKSDVWSFGVVLWEIFSLGGMPYASIPNEELYSKLLDDAYRMPRPELASGNLYAIMERC 735

Query: 500 WKKDPEERPTFEYLQGFLE 518
           W   P +RP F  L G ++
Sbjct: 736 WLNRPSDRPEFSQLVGHID 792
>17300
          Length = 480

 Score =  123 bits (308), Expect(2) = 3e-33,   Method: Compositional matrix adjust.
 Identities = 56/117 (47%), Positives = 83/117 (70%), Gaps = 4/117 (3%)
 Frame = +1

Query: 371 VAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDN----EYTARQGAKFP 426
           +++GM  +  M Y+HRDL + NILV   L+CK+ADFGL+R IE +     YT + G K P
Sbjct: 1   ISSGMGXLADMGYVHRDLAARNILVNEILVCKVADFGLSREIESDTTEGAYTTK-GGKIP 177

Query: 427 IKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMP 483
           ++WTAPEA  Y +FT  SDVWSFG+++ E+++ G  PY   +N++V++ VE+GYR+P
Sbjct: 178 VRWTAPEAIAYRKFTSASDVWSFGVVMWEVMSYGERPYWNWSNQDVIKAVEKGYRLP 348

 Score = 37.4 bits (85), Expect(2) = 3e-33,   Method: Composition-based stats.
 Identities = 16/43 (37%), Positives = 23/43 (53%), Gaps = 1/43 (2%)
 Frame = +2

Query: 484 CPQ-DCPISLHELMIHCWKKDPEERPTFEYLQGFLEDYFTATE 525
           CP  DCP +LH+LM+  W+K+   RP    +   L+    A E
Sbjct: 344 CPSMDCPEALHQLMLDAWQKERSHRPKMSMVVKTLDKLIRAPE 472
>20640
          Length = 1492

 Score =  125 bits (313), Expect = 6e-29,   Method: Compositional matrix adjust.
 Identities = 59/144 (40%), Positives = 86/144 (59%), Gaps = 1/144 (0%)
 Frame = +1

Query: 383 YIHRDLRSANILVGNGLICKIADFGLARLIED-NEYTARQGAKFPIKWTAPEAALYGRFT 441
           Y+HRDL + N LVG+ L+ KI+DFGLAR +   + Y   +    PI+W   EA LY +F+
Sbjct: 7   YVHRDLATRNCLVGHDLVVKISDFGLARSVHSVDYYRGSEHDAIPIRWMPLEAILYNKFS 186

Query: 442 IKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMIHCWK 501
            +SDVWSFG++L E+      PY G+ + EV+  V+ G  + CP+  P  ++ELM  CW 
Sbjct: 187 TQSDVWSFGVVLWEIFAFALQPYYGLTHEEVVRFVKEGKVLACPERTPPPMYELMKQCWH 366

Query: 502 KDPEERPTFEYLQGFLEDYFTATE 525
           + P  RP+F  L   LE+  +  E
Sbjct: 367 RRPATRPSFHTLHKTLENMHSKYE 438
>07291
          Length = 833

 Score =  122 bits (306), Expect = 3e-28,   Method: Compositional matrix adjust.
 Identities = 60/167 (35%), Positives = 98/167 (58%), Gaps = 2/167 (1%)
 Frame = +1

Query: 356 GRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLA-RLIED 414
            + L +  L+D   Q+A GMAY++ +  +HR+L + N +V      +++D+G+   L   
Sbjct: 31  SKMLTVVQLLDFGRQIADGMAYLQEVKVVHRNLAARNCIVTEDGRLQLSDYGVTGSLFPQ 210

Query: 415 NEYTARQG-AKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVL 473
           + YTA    A+  +KW APE      F+ KSDVW+FG++L EL+T+G  PYP + N  +L
Sbjct: 211 SYYTADDSPARDLVKWMAPETIDNFHFSSKSDVWAFGVVLWELLTRGITPYPDVENSSLL 390

Query: 474 EQVERGYRMPCPQDCPISLHELMIHCWKKDPEERPTFEYLQGFLEDY 520
             ++ G+RM  P+  P  ++E+M  CW + PE+RP F  L   L+ +
Sbjct: 391 PYLKEGHRMKKPKQSPEPVYEMMTACWNESPEQRPDFAELNDQLKTF 531
>14116
          Length = 1017

 Score =  121 bits (304), Expect = 7e-28,   Method: Compositional matrix adjust.
 Identities = 72/216 (33%), Positives = 121/216 (56%), Gaps = 13/216 (6%)
 Frame = -1

Query: 263 VARDSLFLEKKLGQGCFAEVWLGTWN-----GNTKVAIKTL---KPGTMSPESFLEEAQI 314
           + R+ L + +++G+G F  V  G        G+  VA+KTL    P  +  +SFL+EA I
Sbjct: 645 IDREFLTMGEEIGKGNFGCVKRGFLTLPEQKGDILVAVKTLHNNNPREIELQSFLQEALI 466

Query: 315 MKKLKHDKLVQLYAV---VSEEPIYIVTEYMSKGSLLDFLKDGEGRALKLPNLVDMAAQV 371
           MK   H  ++ L  +   + + P+ +V  +M  G LL +++D + +   + +L+     +
Sbjct: 465 MKDFHHSNVLTLIGICLNLDDMPL-VVLPFMKHGDLLTYIRDDQHQP-TIKDLIMYGVDI 292

Query: 372 AAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQG--AKFPIKW 429
           A GM Y+  + ++HRDL + N ++      K+ADFGLAR I + EY + +   AK P+KW
Sbjct: 291 ARGMDYLAGLKFVHRDLAARNCMLDEDFHVKVADFGLARDIYEKEYYSSENKKAKLPVKW 112

Query: 430 TAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYP 465
            A E+   G +  K+DVWS+G++L EL+T+G    P
Sbjct: 111 MALESLEKGNYDSKTDVWSYGVVLWELLTRGSDALP 4
>07940
          Length = 1336

 Score =  102 bits (255), Expect = 3e-22,   Method: Compositional matrix adjust.
 Identities = 79/277 (28%), Positives = 119/277 (42%), Gaps = 70/277 (25%)
 Frame = -3

Query: 261 WEVARDSLFLEKKLGQGCFAEVWLGTW------NGNTKVAIKTLKPGTMSPE--SFLEEA 312
           WE  R+ L L  +LG+G F  V  G        N +  VA+K LK      E    + E 
Sbjct: 857 WEFPRERLVLGDRLGEGAFGLVMKGEAMGIFKDNNSVTVAVKMLKEDATDREMMDLIREM 678

Query: 313 QIMKKL-KHDKLVQ----------LYAVVSEEPIYIVTEYM------------------- 342
           ++MK + KH  ++           LY +V   P   + +++                   
Sbjct: 677 EMMKVIGKHKNIINLLGCCTQRGALYVIVEFAPHGNLRDFLKSHRPHGTSYSCIADYEQP 498

Query: 343 ------------------SKGSLLDFL-------------KDGEGRALKLPNLVDMAAQV 371
                             ++G+ L F+             +    + L   +L+  A QV
Sbjct: 497 VITSSSSSFSHPNSASSSAQGTSLGFIPGTSTVSFSTGSHRQDMLKMLTPKDLISYAYQV 318

Query: 372 AAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQ-GAKFPIKWT 430
           A GM Y+     IHRDL + N+LV    + KIADFGL R ++  +Y  +    + P+KW 
Sbjct: 317 ARGMEYLASKQCIHRDLAARNVLVAEEYVLKIADFGLTRNLQQFDYYRKTTDGRLPVKWM 138

Query: 431 APEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGM 467
           APEA    ++T KSDVWS+G+LL E+ T G  PYP +
Sbjct: 137 APEALFDRKYTSKSDVWSYGVLLWEIFTLGGNPYPSV 27
>08294
          Length = 1849

 Score =  102 bits (253), Expect = 4e-22,   Method: Compositional matrix adjust.
 Identities = 63/207 (30%), Positives = 98/207 (47%), Gaps = 11/207 (5%)
 Frame = +2

Query: 322  KLVQLYAVVSE-EPIYIVTEYMSKGSLLDFL-----KDGEGRALKLPNL-----VDMAAQ 370
             +V    V  E EP +++TEY   G L  FL      +G GR  ++P L     + M  Q
Sbjct: 890  NIVHFMGVCREAEPHFLITEYCDWGDLKQFLLATRNDNGRGRGTRVPALALSQKLGMGQQ 1069

Query: 371  VAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWT 430
            VAAGM  +     +H DL + N+L+ + +  K+A   L+  +  +EY        P++W 
Sbjct: 1070 VAAGMEALSNQGLVHGDLAARNVLLTSRMQLKVARPALSGDVYASEYYPLHQRLVPLRWL 1249

Query: 431  APEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCPI 490
             PE  L    T   DVW+FG+ L E++    +PY  M++ EVL  ++         D P 
Sbjct: 1250 PPEGVLEDSATTCGDVWAFGVFLWEVLQLADLPYRLMSDEEVLRSLQHSQAALDSPDAPP 1429

Query: 491  SLHELMIHCWKKDPEERPTFEYLQGFL 517
            +L  L+  C  + P +RP F  +   L
Sbjct: 1430 ALLSLLQRCTAQQPSQRPPFSEICSVL 1510
>18996
          Length = 491

 Score = 98.2 bits (243), Expect = 8e-21,   Method: Compositional matrix adjust.
 Identities = 55/136 (40%), Positives = 79/136 (58%), Gaps = 6/136 (4%)
 Frame = +2

Query: 384 IHRDLRSANILVGNGLICKIADFGLARLIE-DNEYTARQGAKFPIKWTAPEAALYGRFTI 442
           IHRDL + NILV    + KI+DFGLA+    D  Y        PIKW +PEA    +F+ 
Sbjct: 2   IHRDLAARNILVDRSCV-KISDFGLAQFANADGYYYGISQRDIPIKWYSPEAIETCKFSS 178

Query: 443 KSDVWSFGILLTELVTKGRVP--YPG--MNNREVLEQVERGYRMPCPQDCPISLH-ELMI 497
            SDVWS+G+ L E+ ++G +P   PG  +   E L ++ +G R+P P+ C   ++ ELM 
Sbjct: 179 YSDVWSYGVTLFEMFSRGEIPNLLPGHDLTQEEFLNRLRKGERLPKPELCSDFVYSELMR 358

Query: 498 HCWKKDPEERPTFEYL 513
            CW + P+ RPTF  +
Sbjct: 359 PCWHEMPKSRPTFHQI 406
>22005
          Length = 873

 Score = 83.6 bits (205), Expect(2) = 1e-20,   Method: Compositional matrix adjust.
 Identities = 59/194 (30%), Positives = 91/194 (46%), Gaps = 44/194 (22%)
 Frame = +1

Query: 308 FLEEAQIMKKLKHDKLVQLYAVVS-EEPIYIVTEYMSKGSLLDFLKDGEGRALKLP---- 362
           F  EA +M    H  +V+L  V +  +P+ ++ E+MSKG L DFL+        LP    
Sbjct: 151 FEREASLMADFDHPNIVKLLGVCAIGKPMCLLFEFMSKGDLNDFLRLCSPENYNLPVSRS 330

Query: 363 -NLVD-------------------------------------MAAQVAAGMAYIERMNYI 384
            NLV                                      ++ Q++AGMAY+ + +Y+
Sbjct: 331 QNLVVDLEDGLRVEVEAEECEKDTQSEDRDCSGMLXTKDQLYISQQISAGMAYLAQKDYV 510

Query: 385 HRDLRSANILVGNGLICKIADFGLARLIEDNEY-TARQGAKFPIKWTAPEAALYGRFTIK 443
           HRDL +   +        I+DFGLAR +   +Y    +    PI+W   EA LY +F+ +
Sbjct: 511 HRDL-ATRTVXSRTT*S*ISDFGLARSVHSVDYYRGSEQDAIPIRWMPLEAILYSKFSTQ 687

Query: 444 SDVWSFGILLTELV 457
           SDVWSFG++L E++
Sbjct: 688 SDVWSFGVVLWEIL 729

 Score = 34.3 bits (77), Expect(2) = 1e-20,   Method: Compositional matrix adjust.
 Identities = 15/42 (35%), Positives = 24/42 (57%)
 Frame = +3

Query: 463 PYPGMNNREVLEQVERGYRMPCPQDCPISLHELMIHCWKKDP 504
           PY G+ + EV+  V+ G  +  P   P  ++ELM  CW++ P
Sbjct: 744 PYYGLTHEEVVNYVKAGKILEQPTKTPHQVYELMKQCWQRRP 869
>01718
          Length = 959

 Score = 96.3 bits (238), Expect = 3e-20,   Method: Compositional matrix adjust.
 Identities = 87/291 (29%), Positives = 138/291 (47%), Gaps = 16/291 (5%)
 Frame = +3

Query: 247 SSCTPQTSGLAKDAWEVARDSLFLEKKLGQGCFAEVWLGTWNGNTKVAIKTLKPGTMSPE 306
           SSC      L      + R   F+ +K+G G F+EV+  T     +V    +   T +  
Sbjct: 102 SSC----QALRHAVSALTRLDDFICEKIGAGFFSEVFKVTHRITGQVMALKMNTMTSNRH 269

Query: 307 SFLEEAQIMKKLKHDKLVQLYAV-VSEEPIYIVTEYMSKGSLLDFLKDGEGRALKLP--N 363
           + L E Q++ +L+H  +++   V V E  ++ +TEY+  G+L   L   E +  +LP   
Sbjct: 270 NMLREVQLLNRLQHANILRFMGVCVHEGQLHALTEYIPSGNLEQLL---EKKDEELPWTQ 440

Query: 364 LVDMAAQVAAGMAYIERMNYIHRDLRSANILV----GNGLICKIADFGLARLIE---DNE 416
            + +   +A G+ Y+    +IHRDL S NIL+     +G    IADFGLA  I    D E
Sbjct: 441 RIQLTLGLARGLDYLHSTRFIHRDLTSKNILIRREDNHGYHAVIADFGLATKIPDPLDKE 620

Query: 417 YTARQGAKFPIKWTAPEAALYGRF-TIKSDVWSFGILLTELVTKGRVP-----YPGMNNR 470
                G+ +   W APE  L G F   ++D++S GI++ E+    R+P      P MNN 
Sbjct: 621 KLPTVGSPY---WMAPE-VLNGHFYNERADLFSVGIIMCEIT--ARIPADPDIMPRMNNF 782

Query: 471 EVLEQVERGYRMPCPQDCPISLHELMIHCWKKDPEERPTFEYLQGFLEDYF 521
            V + V     +     CP+   +L   C + DP++RP    +  +LE  F
Sbjct: 783 GV-DYVALSEMI---SYCPLDYLQLAFKCCQVDPQKRPRGVEIIEWLEKIF 923
>17637
          Length = 447

 Score = 92.4 bits (228), Expect = 4e-19,   Method: Compositional matrix adjust.
 Identities = 46/132 (34%), Positives = 74/132 (56%), Gaps = 1/132 (0%)
 Frame = +1

Query: 392 NILVGNGLICKIADFGLARLIEDNEYTARQGAKF-PIKWTAPEAALYGRFTIKSDVWSFG 450
           N ++ + L  K+ D  L+R +   +Y      ++ PIKW + EA     +   SDVWSFG
Sbjct: 1   NCVIDDQLRVKLTDSALSRDLFSGDYNCLGDGEYRPIKWLSLEALQKSHYNEGSDVWSFG 180

Query: 451 ILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMIHCWKKDPEERPTF 510
           +L+ E+ T G++PY  ++  E+   ++ GYR+  P +CP  L  +M +CW   P ERP+F
Sbjct: 181 VLMWEMCTLGKLPYAEIDPYEMEHYLKDGYRLAQPFNCPDELFTIMAYCWASMPAERPSF 360

Query: 511 EYLQGFLEDYFT 522
             LQ  L ++ T
Sbjct: 361 SQLQICLSEFHT 396
>13592
          Length = 980

 Score = 91.7 bits (226), Expect = 8e-19,   Method: Compositional matrix adjust.
 Identities = 70/252 (27%), Positives = 130/252 (51%), Gaps = 17/252 (6%)
 Frame = +2

Query: 273 KLGQGCFAEVWLGTWNGNTKV-AIK--TLKPG-TMSPESFLEEAQIMKKLKHDKLVQLYA 328
           K+GQG F +V+    N   ++ A+K   ++PG T + ++  EE +I++ +KH  LV+ Y 
Sbjct: 5   KIGQGRFGKVYTAVNNNTGELMAMKEIAIQPGETRALKNVAEELKILEGIKHKNLVRYYG 184

Query: 329 V-VSEEPIYIVTEYMSKGSLLDFLKDGEGRALKLPNLVD--MAAQVAAGMAYIERMNYIH 385
           + V  E + I  E  S+G+L   ++   G    LP  +     AQ+ +G+A + +   +H
Sbjct: 185 IEVHREELLIFMELCSEGTLESLVELTGG----LPEALSRRFTAQLLSGVAELHKHGIVH 352

Query: 386 RDLRSANILVGNGL-ICKIADFGLARLIEDNE--------YTARQGAKFPIKWTAPEAAL 436
           RD+++ANI + +G    K+ DFG A  I+ +         Y   Q    P  +T   +  
Sbjct: 353 RDIKTANIFLVDGSNSLKLGDFGSAVKIQAHTTVPGELQGYVGTQAYMAPEVFTKTNSDG 532

Query: 437 YGRFTIKSDVWSFGILLTELVTKGRVPYPGMN-NREVLEQVERGYRMPCPQDCPISLHEL 495
           +GR    +D+WS G ++ E+ + G+ P+   + N +++ +V  G +   P+      H+ 
Sbjct: 533 HGRL---ADIWSVGCVVVEMAS-GKRPWAQFDSNFQIMFKVGMGEKPQAPESLSQEGHDF 700

Query: 496 MIHCWKKDPEER 507
           + HC + DP++R
Sbjct: 701 IDHCLQHDPKQR 736
>14477
          Length = 493

 Score = 89.0 bits (219), Expect = 5e-18,   Method: Composition-based stats.
 Identities = 55/160 (34%), Positives = 89/160 (55%), Gaps = 8/160 (5%)
 Frame = -1

Query: 271 EKKLGQGCFAEVWLGTWNGNTK---VAIKTLKPGTMSPE---SFLEEAQIMKKLKHDKLV 324
           E KLG G F  V  G    + +   VAIK LK   + P      ++EA++MKK+ H  +V
Sbjct: 475 ELKLGAGNFGSVMKGVCRLDDREIPVAIKVLKNADLDPSVQSELIKEAEVMKKMDHMHIV 296

Query: 325 QLYAVVSEEPIYIVTEYMSKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYI 384
           +L  +   E + +V E    G L  FL   + + L L N++++  QV+ GM Y+E   ++
Sbjct: 295 RLIGLCEGETMMLVLELAKLGPLNKFLP--KNKHLPLWNILELMWQVSQGMEYLEANKFV 122

Query: 385 HRDLRSANILVGNGLICKIADFGLARLI--EDNEYTARQG 422
           HRDL + NIL+ +    KI+DFG+++ +  E+N Y A++ 
Sbjct: 121 HRDLAARNILLCDEHFAKISDFGMSKTLSRENNYYMAQEA 2
>13305
          Length = 549

 Score = 81.3 bits (199), Expect = 8e-16,   Method: Compositional matrix adjust.
 Identities = 34/97 (35%), Positives = 58/97 (59%)
 Frame = +2

Query: 422 GAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYR 481
             + PI+W A E+     +T +SDVWSFG++L E+ T G  PY   + +++   ++ GYR
Sbjct: 2   STRVPIRWMAVESLFNNTYTTQSDVWSFGVVLWEIFTLGGTPYSSTDTQQLFAFLKDGYR 181

Query: 482 MPCPQDCPISLHELMIHCWKKDPEERPTFEYLQGFLE 518
           +  P+ C  + + +M+ CW ++ + RPTF  L G L+
Sbjct: 182 LKRPKLCDQNTYAMMLQCWNENAQRRPTFPELCGRLQ 292
>19301
          Length = 712

 Score = 79.3 bits (194), Expect = 4e-15,   Method: Compositional matrix adjust.
 Identities = 50/153 (32%), Positives = 82/153 (53%), Gaps = 3/153 (1%)
 Frame = +2

Query: 258 KDAWEVARDSLFLEKKLGQGCFAEVWLGTWNGNTKVAIKTLKPGTMSPESFLEEAQI--M 315
           +D WE+  +S+   + LG G    V+LG      +VA+K ++         ++E  I  +
Sbjct: 281 QDDWEIPFESITDLEWLGSGAQGAVFLGKLCAE-EVAVKKVRD--------IKETDIRNL 433

Query: 316 KKLKHDKLVQLYAVVSEEPIY-IVTEYMSKGSLLDFLKDGEGRALKLPNLVDMAAQVAAG 374
           +KL H  ++    V ++ P Y I+ EY   G L + L+DG+     L  ++D + Q+A+G
Sbjct: 434 RKLNHPNIISFKGVCTQAPCYCIIMEYCPYGQLYEVLRDGKEIPPAL--VLDWSKQIASG 607

Query: 375 MAYIERMNYIHRDLRSANILVGNGLICKIADFG 407
           M Y+     IHRDL+S N+LV    + KI+DFG
Sbjct: 608 MNYLHSHKIIHRDLKSPNVLVAKNDVVKISDFG 706
>01756
          Length = 1858

 Score = 77.4 bits (189), Expect = 1e-14,   Method: Compositional matrix adjust.
 Identities = 60/212 (28%), Positives = 94/212 (44%), Gaps = 22/212 (10%)
 Frame = -3

Query: 273  KLGQGCFAEVWLGTWNGNTKVAIKTLKPGTMS------PESFLEEAQIMKKLKHDKLVQL 326
            K+GQG F EV+        +V    +K   M       P + L E +I++ L H+ +V L
Sbjct: 1721 KIGQGTFGEVFKARCKKTKQVV--AMKKVLMDNEKEGFPITALREIKILQLLNHENVVDL 1548

Query: 327  YAVVSEEP---------IYIVTEYMSKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAY 377
              + S +           Y+V E+      L  L         LP + ++  Q+  G+ Y
Sbjct: 1547 IEICSTKATSANRYKSMFYLVFEFCEHD--LAGLLSNMSVVFNLPEIKEVMKQLMNGLYY 1374

Query: 378  IERMNYIHRDLRSANILVGNGLICKIADFGLAR-----LIEDNEYTARQGAKFPIKWTAP 432
            I R   +HRD+++ANIL+    + K+ADFGLAR     L + N YT R        W  P
Sbjct: 1373 IHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNR----VVTLWYRP 1206

Query: 433  EAALYG--RFTIKSDVWSFGILLTELVTKGRV 462
               L G   ++   D W  G ++ E+ T+  +
Sbjct: 1205 PELLLGDRNYSTAIDQWGAGCIMAEMWTRNPI 1110
>00715
          Length = 1788

 Score = 76.6 bits (187), Expect = 3e-14,   Method: Compositional matrix adjust.
 Identities = 62/223 (27%), Positives = 103/223 (46%), Gaps = 31/223 (13%)
 Frame = +1

Query: 318 LKHDKLVQLYAVVS----EEPIYIVTEYMSKGSLLDFLKDGEGRALKLPNLVDMAAQVAA 373
           L+H  +V +    S    E+  ++  EY+   +L   L D + + +     + +A Q+A 
Sbjct: 97  LRHVNVVSILGATSLHRFEDGAWLAMEYVGPLNLQTILNDHQ-QDIDSSMRLSLALQMAR 273

Query: 374 GMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLI----------------EDNEY 417
           G+ Y+  +N +H DL+ AN L+   L  +IADFG    +                 + E 
Sbjct: 274 GLHYLHSINIVHLDLKPANCLLTRDLKLRIADFGCCHQLTPTGLDMGEREGGMAGNELEL 453

Query: 418 TARQGA-----KFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREV 472
           T  QGA        + + APE     + +++SDV+S GI L ++ T+ + PY G+    V
Sbjct: 454 TPVQGAWKNELAGTLAYRAPELLKGLQPSVRSDVYSLGITLWQMCTR-QGPYEGVPAHAV 630

Query: 473 LEQVERGYRMPCP----QDCP--ISLHELMIHCWKKDPEERPT 509
           + QV      PCP    +D P  +   +L   CW +  E+RPT
Sbjct: 631 VYQVVSKDLRPCPPPSTEDDPFEVMFRDLYTQCWARRVEDRPT 759
>12721
          Length = 821

 Score = 71.2 bits (173), Expect = 9e-13,   Method: Compositional matrix adjust.
 Identities = 51/217 (23%), Positives = 100/217 (46%), Gaps = 3/217 (1%)
 Frame = +1

Query: 273 KLGQGCFAEVWLGTWNGNTKVAIKTLKPGTMSPESFL-EEAQIMKKLKHDKLVQLYA--V 329
           K+G+G    V + T     ++A+K +          L  E  +M+   H  +V++Y   +
Sbjct: 109 KIGEGSTGIVCIATSRDGRQMAVKKMDLRKQQRRELLFNEVVVMRDYHHPNIVEMYNSYL 288

Query: 330 VSEEPIYIVTEYMSKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLR 389
           V++E +++V E+M  G+L D + +     +++  +     +    +A++     IHRD++
Sbjct: 289 VNDE-LWVVMEFMEGGALTDIVTNNRMDEVQIATVCRACLK---ALAFLHANGVIHRDIK 456

Query: 390 SANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSF 449
           S +IL+ +    K+ DFG    +  +    +     P  W APE      +  + D+WS 
Sbjct: 457 SDSILLSHDGKVKLXDFGFCAQVTQDLQKRKSLVGTPY-WMAPEVISRLPYGPEVDIWSL 633

Query: 450 GILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQ 486
           GI++ E++       P   N   L+ + R   MP P+
Sbjct: 634 GIMVMEMIDAE----PPFFNEPPLQAMRRIRDMPPPK 732
>17253
          Length = 483

 Score = 70.5 bits (171), Expect = 2e-12,   Method: Composition-based stats.
 Identities = 45/153 (29%), Positives = 69/153 (45%), Gaps = 16/153 (10%)
 Frame = -1

Query: 293 VAIKTLKPGTMSPE--SFLEEAQIMKKL-KHDKLVQLYAVVS-EEPIYIVTEYMSKGSLL 348
           VA+KT        E   FL E  IM+KL +H  +V      +  +P  I+ E+   G LL
Sbjct: 459 VAVKTHNEAATDAEKSEFLRELSIMRKLPRHPNVVSFMGCCTMSDPALILMEFCCHGDLL 280

Query: 349 DFLKD----------GEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNG 398
            FL+                L   +    A  VA GMA++     +HRD+ + N+L+   
Sbjct: 279 SFLRKRRPDRTVFLTSTANDLTARDFFSFALHVARGMAHVANNKIVHRDVAARNVLISER 100

Query: 399 LICKIADFGLARLIEDNE--YTARQGAKFPIKW 429
            +CK++DFGL+R + D    Y        P++W
Sbjct: 99  NVCKVSDFGLSRRVGDQNDVYEIVSRRPLPLRW 1
>01060
          Length = 1800

 Score = 69.7 bits (169), Expect = 3e-12,   Method: Compositional matrix adjust.
 Identities = 63/255 (24%), Positives = 117/255 (45%), Gaps = 13/255 (5%)
 Frame = +1

Query: 261 WEVARDSLFLEKKLGQGCFAEVW------LGTWNGNTKVAIKTLKPGTMSPESFLEEAQI 314
           +E A   L   +K+G+G +  V+       G      K+ ++  + G   P S + E  +
Sbjct: 58  FETALSDLTDFQKIGEGTYGVVYKCRHRATGRKLAMKKIRLRGSEDGV--PSSAIREIAM 231

Query: 315 MKKLKHDKLVQLYAVVSE-EPIYIVTEYMSKGSLLDFLKDGEGRALKLPNLVDMAAQVAA 373
           +++L+H  +V L  V+ E E +++V E++S    +   K  EG  L    +     Q+  
Sbjct: 232 LRELRHTNIVCLEDVIMEDERLFLVFEFLSMDLKMYIDKFPEGVVLDRRLVKSYVFQIVT 411

Query: 374 GMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPE 433
           G+ +  +   +HRDL+  N+L+ +    KIADFG+AR        A       + + APE
Sbjct: 412 GIXFCHQRRIVHRDLKPQNLLINHTGAIKIADFGMARTFA-LPVRAYTHEVVTLWYRAPE 588

Query: 434 AAL-YGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCPISL 492
             +   +++   DVWS G +  +++ +  + + G +  + L ++ R    P  Q  P   
Sbjct: 589 ILMGASKYSTPVDVWSIGTIFADMLIRTPI-FKGDSEIDQLFKIFRIIGTPTEQTWP-EF 762

Query: 493 HEL-----MIHCWKK 502
           H+L     M   WK+
Sbjct: 763 HKLPAFNGMFPLWKE 807
>01707
          Length = 757

 Score = 67.8 bits (164), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 63/216 (29%), Positives = 109/216 (50%), Gaps = 10/216 (4%)
 Frame = +1

Query: 273 KLGQGCFAEVWLGTWNGNTK--VAIKTLKPGTMSP---ESFLEEAQIMKKLKHDKLVQLY 327
           K+G+G +  V+    N  T   VAIK        P   +  + E +++K+LKH  LV+L 
Sbjct: 85  KIGEGSYGVVF-KCRNKETSQLVAIKKFVESEDDPLIKKIAMREIRMLKQLKHPNLVRLI 261

Query: 328 AVVSEEP-IYIVTEYMSKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHR 386
            V   +  +++V +Y+   +LL+ L D   R L  P +  +  Q    + +  + N IHR
Sbjct: 262 EVFRRKKRLHLVFDYVDH-TLLNEL-DRYPRGLPEPMVKRIIYQTLLAVNFCHQYNTIHR 435

Query: 387 DLRSANILVGNGLICKIADFGLARLIE--DNEYTARQGAKFPIKWTAPEAALYG--RFTI 442
           D++  NIL+      K+ DFG AR++    +EYT     ++   + APE  L G  ++  
Sbjct: 436 DVKPENILITRQGQVKLCDFGFARILTGPGDEYTDYVATRW---YRAPE-LLVGDTQYGP 603

Query: 443 KSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVER 478
             DVW+ G +  EL+T G+  +PG ++ + L  + +
Sbjct: 604 PVDVWAIGCVFAELLT-GQALWPGRSDVDQLHLIRK 708
>18921
          Length = 697

 Score = 67.4 bits (163), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 53/193 (27%), Positives = 89/193 (46%), Gaps = 2/193 (1%)
 Frame = +2

Query: 273 KLGQGCFAEVWLGTWNGNTKV-AIKTLKPGTMSPESFLEEAQIMKKLKHDKLVQLY-AVV 330
           KLG+G +  V+        +V AIK + P     +  ++E  IM++     +V+ Y +  
Sbjct: 50  KLGEGSYGSVFKSLHKETGQVLAIKQV-PVDTDLQEIIKEISIMQQCDSKYIVKYYGSYF 226

Query: 331 SEEPIYIVTEYMSKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRS 390
               ++IV EY   GS+ D ++    + L    +  +      G+ Y+     IHRD+++
Sbjct: 227 KNTDLWIVMEYCGAGSVSDIMRL-RNKTLVEREIATILYYTLKGLXYLHSRRKIHRDIKA 403

Query: 391 ANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFG 450
            NIL+ N    K+ADFG+A  + D           P  W APE      +   +D+WS G
Sbjct: 404 GNILLNNEGHAKLADFGVAGQLTDTMAKRNTVIGTPY-WMAPEVIQEIGYDCVADIWSLG 580

Query: 451 ILLTELVTKGRVP 463
           I   E+  +G+ P
Sbjct: 581 ITALEM-AEGKPP 616
>29581
          Length = 1278

 Score = 66.2 bits (160), Expect = 3e-11,   Method: Compositional matrix adjust.
 Identities = 59/191 (30%), Positives = 91/191 (47%), Gaps = 11/191 (5%)
 Frame = -2

Query: 298  LKPGTMSPESFLEEAQIMKKLKHDKLVQLYAVV---SEEPIYIVTEYMSK--GSLLDFLK 352
            L+   +SP      +  +  L+H  +VQL  VV   S + +++V EY  +   SLLD + 
Sbjct: 1244 LERDMVSPSVVCVRSTFLLNLRHQNIVQLQEVVVGKSLDSLFLVMEYCEQDLASLLDNMP 1065

Query: 353  DGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLI 412
                 +     +  +  Q+  G+ Y+     IHRDL+ +N+L+ +    KIADFGLAR  
Sbjct: 1064 APFSES----QVKCIVLQLLKGLRYLHEAFIIHRDLKVSNLLMTDKGCVKIADFGLAR-- 903

Query: 413  EDNEYTARQGAKFP----IKWTAPEAALYGRFTIKS--DVWSFGILLTELVTKGRVPYPG 466
                Y   Q    P    + + APE  L+G  T  +  D+WS G +L EL+       P 
Sbjct: 902  ---NYGKPQKPMTPKVVTLWYRAPE-LLFGSKTHSTAIDMWSAGCILGELLGHK----PL 747

Query: 467  MNNREVLEQVE 477
            M  R  L+Q+E
Sbjct: 746  MPGRSDLQQIE 714
>00300
          Length = 2318

 Score = 63.2 bits (152), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 57/251 (22%), Positives = 117/251 (46%), Gaps = 16/251 (6%)
 Frame = -1

Query: 273  KLGQGCFAEVWLGT-WNGNTKVAIKTLK--PGTMSP-ESFLEEAQIMKKLKHDKLVQLYA 328
            K+G+G F +V+     +    +A+K +K  P  +       +E +I + ++H+ LV+ Y 
Sbjct: 1637 KIGEGQFGKVYTAVNMSTGELMALKEMKFQPNDLQQLREMCDEIKIFEGIQHENLVKYYG 1458

Query: 329  V-VSEEPIYIVTEYMSKGSLLDFLKDGEGRALKLPN--LVDMAAQVAAGMAYIERMNYIH 385
            V V ++ + +  EY   G++ +  K G      LP   +     ++   + ++   + +H
Sbjct: 1457 VEVHKDEMLMFMEYCDTGTIEEAAKMG------LPEYLIRRYTREIVLAVNHLHENSIVH 1296

Query: 386  RDLRSANILVGNGLICKIADFGLARLIEDN-----EYTARQGAK---FPIKWTAPEAALY 437
            RD++ ANI + +    K+ DFG +  ++ +     E+    G      P  +T  +   Y
Sbjct: 1295 RDIKGANIFLTSNGHVKLGDFGCSVKLKSHTTMPGEFHNLVGTTAYMAPEVFTQNDQGGY 1116

Query: 438  GRFTIKSDVWSFGILLTELVTKGRVPYPGM-NNREVLEQVERGYRMPCPQDCPISLHELM 496
            GR    +D+WS G ++ E+ T G+ P+  + NN +++ +V  G++   P    +     +
Sbjct: 1115 GR---AADIWSLGCVVIEMAT-GKRPWHDLDNNYQIMYKVGIGHKPAVPDSLSVEGKHFL 948

Query: 497  IHCWKKDPEER 507
                  DP +R
Sbjct: 947  DLIMCHDPAQR 915
>25550
          Length = 941

 Score = 63.2 bits (152), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 29/60 (48%), Positives = 40/60 (66%)
 Frame = +3

Query: 462 VPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMIHCWKKDPEERPTFEYLQGFLEDYF 521
           V YPG++  EV   +ERGYRM  PQ  P  ++ LM+ CW+ DP+ERPTF+ +   LE+ F
Sbjct: 36  VXYPGVDLTEVYHLLERGYRMERPQGTPADVYILMLKCWQWDPKERPTFKEIHYLLENMF 215
>18484
          Length = 635

 Score = 62.8 bits (151), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 37/122 (30%), Positives = 65/122 (53%)
 Frame = +1

Query: 355 EGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIED 414
           EG+  K P     AA++A G+ ++     I+RDL+  N+++ +    KIADFG+ +    
Sbjct: 25  EGK-FKEPVAAFYAAEIAVGLFFLHDQGIIYRDLKLDNVMLDSEGHIKIADFGMCKEGMT 201

Query: 415 NEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLE 474
            + T R     P  + APE  LY  ++   D W++G+LL E++  G+ P+ G +  E+  
Sbjct: 202 GDATTRTFCGTP-DYIAPEIVLYQPYSKSVDWWAYGVLLFEMLA-GQPPFDGEDEDELFS 375

Query: 475 QV 476
            +
Sbjct: 376 SI 381
>14420
          Length = 528

 Score = 62.8 bits (151), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 40/166 (24%), Positives = 81/166 (48%), Gaps = 3/166 (1%)
 Frame = +2

Query: 306 ESFLEEAQIMKKLKHDKLVQ-LYAVVSEEPIYIVTEYMSKGSLLDFLKDGEGRALKLPNL 364
           E  + E  +M++ ++  +V  L + +  E +++V E+++ GSL D + +     +    +
Sbjct: 35  ELIINEILVMRENQNPNIVNYLDSYLVGEELWVVMEFLAGGSLTDVVTE---TCMDEGQI 205

Query: 365 VDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLI--EDNEYTARQG 422
             +  +    + ++     IHRD++S NIL+G     K+ DFG    +  E ++ +   G
Sbjct: 206 AAVCRECLQALEFLHENQVIHRDIKSDNILLGMDGSVKLTDFGFCAQLSPEQSKRSTMVG 385

Query: 423 AKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMN 468
             +   W APE     ++    D+WS G++  E++ +G  PY   N
Sbjct: 386 TPY---WMAPEVVTRKQYGPTVDIWSLGVMCIEMI-EGEPPYLNEN 511
>14126
          Length = 1265

 Score = 61.2 bits (147), Expect = 9e-10,   Method: Compositional matrix adjust.
 Identities = 57/236 (24%), Positives = 106/236 (44%), Gaps = 16/236 (6%)
 Frame = +3

Query: 274 LGQGCFAEVWLG--TWNGNTKVAIKTLKPGTMS---PESFLEEAQIMKKLK---HDKLVQ 325
           +G G +  V+      N    VA+K ++        P   + E  ++K+L+   H  +V+
Sbjct: 213 IGNGAYGTVYKARDLRNQGEFVAMKRIRLNNTEEGMPMMAIREISMLKQLEQYEHPNVVR 392

Query: 326 LYAVV------SEEPIYIVTEYMSKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIE 379
           L  V        E  + +V EY+ +  L  +L       L    + D+  Q+  G+ ++ 
Sbjct: 393 LLDVSHNTITDREIRLNLVFEYI-EHDLATYLAKCPSPGLGPDRIKDLMLQLLNGVDFLH 569

Query: 380 RMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGR 439
               +HRDL+  N+L+      K+ADFGLAR+   + + A       + + +PE  +   
Sbjct: 570 SNRIVHRDLKPQNLLISKDGRLKLADFGLARIY--SFHMALTTVVVTLWYRSPEVLMQAE 743

Query: 440 FTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCP--ISLH 493
           +    D+WS G +  EL T+ R  + G +  + L+++     +P   D P  +S+H
Sbjct: 744 YGTSVDIWSCGCIFAELFTR-RALFKGSSEFDQLKKIFEVIGLPPAGDWPEGVSVH 908
>27546
          Length = 426

 Score = 61.2 bits (147), Expect = 1e-09,   Method: Composition-based stats.
 Identities = 36/114 (31%), Positives = 56/114 (49%), Gaps = 7/114 (6%)
 Frame = -1

Query: 308 FLEEAQIMKKLKHDKLVQLYAVVSEEP-IYIVTEYMSKGSLLDFLKDGEGRALKLPNLVD 366
           F  E +I+ +L H  ++Q+++++   P I+I   Y  KG +L  +K            +D
Sbjct: 339 FPRELEILTRLDHPNIIQIHSILQRGPKIFIFMRYAEKGDMLSHIKK--------TGPID 184

Query: 367 MAA------QVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIED 414
            A       Q+A  + Y+   +  HRDL+  NIL+   L  KIADFG AR   D
Sbjct: 183 EAQTKVWFFQMAKALQYLHSHDIAHRDLKCENILLSKRLNVKIADFGFARYCRD 22
>04591
          Length = 1117

 Score = 60.5 bits (145), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 44/169 (26%), Positives = 82/169 (48%), Gaps = 14/169 (8%)
 Frame = -2

Query: 305  PESFLEEAQIMKKLKHDKLVQLYAVVSEEP---------IYIVTEYMS--KGSLLDFLKD 353
            P + L E +I+++L+H+ +VQL  +   +           Y++ EY       LL+ L+ 
Sbjct: 1089 PITALREIKILQQLEHENVVQLQEICHTQAGPYNRYKSTFYLIFEYCDYDLAGLLNNLR- 913

Query: 354  GEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLAR-LI 412
                   L +  ++ +Q+  G+ YI     +HRD+++ANIL+    + K+ADFGL+R  +
Sbjct: 912  ---VKFSLADKKNLMSQLLNGLFYIHTKQILHRDIKAANILLTRDGVLKLADFGLSRPWV 742

Query: 413  EDNEYTARQGAKFPIKWTAPEAALYG--RFTIKSDVWSFGILLTELVTK 459
            +    T R        W  P   L G   +  + D+W  G ++ E+ ++
Sbjct: 741  KSKRLTNR----VVTLWYRPPELLLGEREYGPEIDMWGVGCIMAEMWSR 607
>01966
          Length = 1735

 Score = 59.7 bits (143), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 33/107 (30%), Positives = 58/107 (54%), Gaps = 1/107 (0%)
 Frame = -1

Query: 305  PESFLEEAQIMKKLKHDKLVQLYAVVSE-EPIYIVTEYMSKGSLLDFLKDGEGRALKLPN 363
            P S + E  ++++L+H  +V L  V+ E E +++V E++S    +   K  EG  L    
Sbjct: 1582 PSSAIREIAMLRELRHTNIVCLEDVIMEDERLFLVFEFLSMDLKMYIDKFPEGVVLDRRL 1403

Query: 364  LVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLAR 410
            +     Q+  G+ +  +   +HRDL+  N+L+ +    KIADFG+AR
Sbjct: 1402 VKSYVFQIVTGINFCHQRRIVHRDLKPQNLLINHTGAIKIADFGMAR 1262
>00392
          Length = 668

 Score = 58.9 bits (141), Expect = 5e-09,   Method: Compositional matrix adjust.
 Identities = 53/174 (30%), Positives = 89/174 (51%), Gaps = 10/174 (5%)
 Frame = +3

Query: 306 ESFLEEAQIMKKLKHDKLVQLYAVVSE------EPIYIVTEYMSKGSLLDFLKDGEGRAL 359
           + F EEA+++K+L+H  +V+ +    E      + I +VTE M+ G+L  +LK  +   +
Sbjct: 66  QRFKEEAEMLKELQHPNIVRFFDYWEEHNHRNRKVIILVTELMTSGTLKTYLKRFKKPNV 245

Query: 360 KLPNLVDMAAQVAAGMAYIERMN--YIHRDLRSANILV-GNGLICKIADFGLARLIEDNE 416
           K+  L +   QV  G+ ++       IHRDL+  NI + G     KI D GLA L   N+
Sbjct: 246 KI--LKNWCRQVLKGLYFLHTRTPPVIHRDLKCDNIFITGPTGSVKIGDLGLATL--KNQ 413

Query: 417 YTARQGAKFPIKWTAPEAALY-GRFTIKSDVWSFGILLTELVTKGRVPYPGMNN 469
             A+     P ++ APE  +Y   +    DV++FG+ + E+ +    PY   +N
Sbjct: 414 SFAKSVIGTP-EFMAPE--MYEEHYDEAVDVYAFGMCMLEMAS-SEYPYSECSN 563
>11228
          Length = 2155

 Score = 58.2 bits (139), Expect = 9e-09,   Method: Compositional matrix adjust.
 Identities = 41/149 (27%), Positives = 75/149 (50%), Gaps = 5/149 (3%)
 Frame = -2

Query: 88   VALYDYEARTE-DDLSFHKGEKFQILNSSEGDWWEARSLTTGETGYIPSNYVAPVDS--- 143
            VA+  Y   T+ D+LSF KG+ F + N  E  W       T E+G +P+ +V  +D    
Sbjct: 1662 VAMLSYRKATDSDELSFCKGDVFVVQNEMEDGWLWVTCERTKESGLVPAPFVKDLDGDYE 1483

Query: 144  -IQAEEWYFGKLGRKDAERQLLSFGNPRGTFLIRESETTKGAYSLSIRDWDDMKGDHVKH 202
             +++  ++   L +++A  +L+  G   G+FL+R+SE   G YSL      D     V+ 
Sbjct: 1482 PVESLPYFHSCLSKEEAVEKLMLAGE--GSFLVRQSENYPGDYSLFFLCEKD-----VRR 1324

Query: 203  YKIRKLDNGGYYITTRAQFETLQQLVQHY 231
            ++I +   G  ++     F++L  +++ Y
Sbjct: 1323 FRIER--RGNQFLVGGRLFDSLDGVIKRY 1243

 Score = 37.0 bits (84), Expect = 0.018,   Method: Compositional matrix adjust.
 Identities = 22/57 (38%), Positives = 31/57 (54%)
 Frame = -1

Query: 132  YIPSNYVAPVDSIQAEEWYFGKLGRKDAERQLLSFGNPRGTFLIRESETTKGAYSLS 188
            +I S   AP   +    WY G+LGR  AE  L       G++L+RESE+  G++ LS
Sbjct: 2011 HINSALTAPDQKL----WYHGRLGRAGAEELLRD--QDAGSYLVRESESKLGSFVLS 1859
>31885
          Length = 529

 Score = 57.4 bits (137), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 46/169 (27%), Positives = 78/169 (46%), Gaps = 6/169 (3%)
 Frame = -2

Query: 312 AQIMKKLKHDKLVQL-YAVVSEEPIYIVTEYMSKGSLLDFLKDGEGRALKLPNLVDMAAQ 370
             ++ +L H  LV L YA   EE +++V +    G L   ++  +  + +   +     Q
Sbjct: 519 VDMLTRLDHPFLVNLWYAFQDEEDLFMVVDLFLGGDLRYHMQ--QEVSFREDCVKFYLCQ 346

Query: 371 VAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWT 430
           +A  + Y+     +HRD++  NIL+     C + DF +A  +ED+E         P  + 
Sbjct: 345 LALVLDYLRSQKIVHRDIKPDNILLDEQGHCHVTDFNIATQLEDDELATSTSGTRP--YM 172

Query: 431 APE---AALYGR--FTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLE 474
           APE    A+  R  +    D WS G+ L EL+ K R P+   +N  + E
Sbjct: 171 APEVYGVAINERRGYGFPVDWWSLGVSLFELLKKRR-PFSVHSNTSLHE 28
>07836
          Length = 1478

 Score = 57.0 bits (136), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 62/217 (28%), Positives = 100/217 (46%), Gaps = 42/217 (19%)
 Frame = -1

Query: 335  IYIVTEYMSKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIE--------RMNYIHR 386
            ++++T+Y   GSL D+L     R L    ++ +A     G+A++         +    HR
Sbjct: 1328 LFLITDYHENGSLHDYLL---SRVLDSSEMLALAHSAICGLAHLHIEIFGTRGKPAIAHR 1158

Query: 387  DLRSANILVGNGLICKIADFGLA-RLI-EDNEYTA----RQGAKFPIKWTAPEAALYGRF 440
            D++S NILV     C IAD GLA R I E NE       RQG K   ++ APE  L    
Sbjct: 1157 DIKSKNILVKKNGTCCIADLGLAVRYISESNEVDVAPNPRQGTK---RYMAPE-VLEMLL 990

Query: 441  TIK-------SDVWSFGILLTEL----VTKG-----RVPY-------PGMNNREVLEQVE 477
             +K       +D+++FG+++ E+    V  G     +VP+       P   +  ++  V+
Sbjct: 989  NVKNFDAFKQADMYAFGLVMWEIARCCVIGGVAEEYQVPFYNCLPHDPSFEDVRLVVSVD 810

Query: 478  RGYRMPCP---QDCPI--SLHELMIHCWKKDPEERPT 509
            +  R   P   Q+ PI   + ++M  CW  +P  R T
Sbjct: 809  K-VRPDIPLRWQEDPIMKVMVKVMCECWSGNPAARLT 702
>13066
          Length = 551

 Score = 56.6 bits (135), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 48/183 (26%), Positives = 81/183 (44%), Gaps = 12/183 (6%)
 Frame = +3

Query: 280 AEVWLGTWNG----NTKVAIKTL----KPGTMSPESFLEEAQIMKKLKHDKLVQLYAVVS 331
           A V  GT+N     N K+A K +     P     + F  E  ++ KL H  ++Q+++++ 
Sbjct: 9   AVVVHGTFNDGYGRNIKLACKIIDKEKAPVDFVEKFFPRELDLLTKLDHPYIIQIHSILQ 188

Query: 332 EEPI-YIVTEYMSKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRS 390
             P  +I   +  +G LL +++  E   +K         Q+   + Y+   +  HRDL+ 
Sbjct: 189 RXPKNFIFMRFAERGDLLTYIQ--EVGFVKEKQAKIWFYQMTTALNYLHSYDVAHRDLKC 362

Query: 391 ANILVGNGLICKIADFGL--ARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIK-SDVW 447
            NIL+ +    K+ADFG   A + E  E    +       + APE      +  K +D W
Sbjct: 363 ENILLSSHFNVKLADFGFACACITESGEKYMSRTYCGSAAYAAPEIVYGAPYAPKVADAW 542

Query: 448 SFG 450
           S G
Sbjct: 543 SLG 551
>09606
          Length = 1300

 Score = 55.8 bits (133), Expect = 4e-08,   Method: Compositional matrix adjust.
 Identities = 52/224 (23%), Positives = 98/224 (43%), Gaps = 23/224 (10%)
 Frame = -3

Query: 266  DSLFLEKKLGQGCFAEVWLGTWNGNTK-VAIKTLKPGTMSPESFLEEAQIMKKLKHDKLV 324
            ++  L ++LG+G  + ++ G   G    VAI  ++     PE      ++   + H  +V
Sbjct: 1115 ENFVLYEELGKGEHSIIYKGRRKGTINFVAIHCIEK-CKRPE-VTNTVRMTHDISHPNVV 942

Query: 325  QLYA-VVSEEPIYIVTEYMSKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNY 383
            Q +    +   +++V E  + GSL D L   +   L   ++ D    +  G+ YI  +  
Sbjct: 941  QFHEWYETSNHLWLVVELCTGGSLADIL--AQDHHLPETSIRDFGIHLVTGLHYIHSLGI 768

Query: 384  IHRDLRSANILVGNGLICKIADFGLARLIEDNEYT-----ARQGAKFPIK---------- 428
            +  DLR + +L+    + K ADFGL+++  +N        A  G ++ I+          
Sbjct: 767  LFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEAGDQWNIQSAEEMMKQVP 588

Query: 429  ------WTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPG 466
                  + APE       +I SD+W+ G +  E+ + G  P+ G
Sbjct: 587  TSGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFS-GHPPFLG 459
>03240
          Length = 1683

 Score = 55.1 bits (131), Expect = 7e-08,   Method: Compositional matrix adjust.
 Identities = 46/161 (28%), Positives = 75/161 (46%), Gaps = 9/161 (5%)
 Frame = -3

Query: 272  KKLGQGCFAEVWLGTWNGNTKV-AIKTLKPGTMSPESFLE----EAQIMKKLKHDKLVQL 326
            K LG G F EV L   N    + A+KTL+   +   + +     E  I+ +  ++ +V+L
Sbjct: 1273 KTLGVGAFGEVSLCRKNDTGMLYAMKTLRKSDVLKRNQVAHVKAERDILAEADNEWVVKL 1094

Query: 327  YAVVSEEP-IYIVTEYMSKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIH 385
            Y    +   +Y V +Y+  G L+  L   E   L  P      A++   +  + RM +IH
Sbjct: 1093 YYSFQDHNYLYFVMDYVPGGDLMGLLIRME--ILDEPLARFYVAELVQAIESVHRMGFIH 920

Query: 386  RDLRSANILVGNGLICKIADFGLA---RLIEDNEYTARQGA 423
            RD++  NIL+      K+ DFGL    R   +++Y  R G 
Sbjct: 919  RDIKPDNILIDRNGHIKLTDFGLCTGFRWTHNSKYYQRDGT 797
>12672
          Length = 773

 Score = 53.5 bits (127), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 40/164 (24%), Positives = 74/164 (45%), Gaps = 16/164 (9%)
 Frame = +3

Query: 372 AAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPI---K 428
           A+G+ Y+    ++HRD+++ANIL+ +    K+ DF         E    Q A   I    
Sbjct: 21  ASGIQYLNDNGHVHRDIKTANILLDSEYTAKVGDFATVVSAPSGEGKTVQNASVVIGTAA 200

Query: 429 WTAPEAALYGRFTIKSDVWSFGILLTELVT----------KGRVPYPGMNNREVLEQVER 478
           + APE A++   + K D +SFG++L E++T          +  +    M N E  E++  
Sbjct: 201 YLAPE-AIHFDVSTKLDSYSFGVVLLEVITGLVAQDYSREERTLSSHIMENVEEPEEIHD 377

Query: 479 GYRMPC---PQDCPISLHELMIHCWKKDPEERPTFEYLQGFLED 519
                    P      L+++ + C     ++RP  + ++  LE+
Sbjct: 378 FVDQSAGTWPDGAVDKLYDISMRCLNLSKKQRPNVKDIRPELEE 509
>13212
          Length = 1067

 Score = 53.1 bits (126), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 45/167 (26%), Positives = 76/167 (45%), Gaps = 11/167 (6%)
 Frame = -1

Query: 370 QVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKF---P 426
           ++   + ++ R + IHRD+++ N+L+      K+ADFG++     N  T ++   F   P
Sbjct: 956 EMCMALDFLHRHHVIHRDIKAGNVLLTIDGEVKLADFGVSA---KNTQTQQKRDTFIGTP 786

Query: 427 IKWTAPEAALY-----GRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERG-- 479
             W APE  L        +  K+D+WS G+ L E   +   P   M+   VL ++ +   
Sbjct: 785 Y-WMAPEVVLCETLKDTPYDFKADIWSLGVTLIEFA-QIEPPNKEMHPMRVLIKIHKSDP 612

Query: 480 YRMPCPQDCPISLHELMIHCWKKDPEERPT-FEYLQGFLEDYFTATE 525
             +  P+       + +  C  KDP  RPT  E L+       TAT+
Sbjct: 611 PTLEKPKKWTKLFKDFIAKCLVKDPNLRPTAAELLEHPFMKRATATD 471
>04138
          Length = 800

 Score = 52.4 bits (124), Expect = 4e-07,   Method: Compositional matrix adjust.
 Identities = 32/93 (34%), Positives = 47/93 (50%), Gaps = 7/93 (7%)
 Frame = +1

Query: 377 YIERMNYIHRDLRSANILVGNGLICKIADFGLAR-----LIEDNEYTARQGAKFPIKWTA 431
           YI R   +HRD+++ANIL+    + K+ADFGLAR     L + N YT R        W  
Sbjct: 58  YIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNR----VVTLWYR 225

Query: 432 PEAALYG--RFTIKSDVWSFGILLTELVTKGRV 462
           P   L G   ++   D W  G ++ E+ T+  +
Sbjct: 226 PPELLLGDRNYSTAIDQWGAGCIMAEMWTRNPI 324
>29243
          Length = 1147

 Score = 51.6 bits (122), Expect = 7e-07,   Method: Compositional matrix adjust.
 Identities = 35/107 (32%), Positives = 55/107 (51%), Gaps = 4/107 (3%)
 Frame = +2

Query: 136 NYVAPVDSIQAEEWYFGKLGRKDAERQLLSFGNPRGTFLIRESETT--KGAYSLSIRDWD 193
           +YV    S+++  WY G + R  A++ L +   P GTFLIR +     +G  SLSI+   
Sbjct: 269 DYVNEPCSLESYNWYVGIMERPVAQKXLDTC--PDGTFLIRVTNNPLRRGELSLSIK--- 433

Query: 194 DMKGDHVKHYKIRKLDNGGYYITTRAQFETLQQLVQHY--SEKADGL 238
               + V+H K+ +   G +Y+     F+ +Q LV HY  +E AD  
Sbjct: 434 --YANAVRHIKVNRNPQGRFYLADGRYFDNIQSLVDHYENNELADSF 568

 Score = 40.4 bits (93), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 20/53 (37%), Positives = 28/53 (52%), Gaps = 2/53 (3%)
 Frame = +2

Query: 88  VALYDYEARTEDDLSFHKGEKFQIL--NSSEGDWWEARSLTTGETGYIPSNYV 138
           VA+YDY A +   LS    ++  IL  N  +  WW+  +L T + GY P  YV
Sbjct: 641 VAVYDYAATSTSQLSMKLNDRIAILSKNGQDKGWWKGENLRTQKIGYFPLAYV 799
>21079
          Length = 878

 Score = 51.2 bits (121), Expect = 9e-07,   Method: Compositional matrix adjust.
 Identities = 39/143 (27%), Positives = 69/143 (48%), Gaps = 4/143 (2%)
 Frame = +1

Query: 320 HDKLVQLY-AVVSEEPIYIVTEYMSKGSLLD-FLKDGEGRALKLPNLVDMAAQVAAGMAY 377
           H KL+ L+ A  +   + +V E++  G L +  ++D     L   + V    Q+ +G+ Y
Sbjct: 1   HPKLLMLWDAFEAPRTMVLVMEFVGAGELFERVIRDD--FVLTERDCVHFVRQICSGVGY 174

Query: 378 IERMNYIHRDLRSANILV--GNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAA 435
           +   + +H DL+  N+L    N    KI DFGLAR  +  +  + Q      ++ APE  
Sbjct: 175 MHTQSILHLDLKPENVLCVSDNSNQIKIIDFGLARFYKPGD--SLQVLFGTPEFIAPEVV 348

Query: 436 LYGRFTIKSDVWSFGILLTELVT 458
            Y      +D+WS G++   L++
Sbjct: 349 NYDEINFTTDMWSIGVICYILLS 417
>12324
          Length = 946

 Score = 48.9 bits (115), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 22/53 (41%), Positives = 32/53 (60%)
 Frame = +3

Query: 88  VALYDYEARTEDDLSFHKGEKFQILNSSEGDWWEARSLTTGETGYIPSNYVAP 140
           VA+YDYEA  +D+L+F +     ++  ++  WWE   +  G TG  PSNYV P
Sbjct: 699 VAIYDYEAEKDDELTFSENSVIYVIRKNDDGWWEG--VMDGVTGLFPSNYVEP 851
>19094
          Length = 898

 Score = 48.5 bits (114), Expect = 7e-06,   Method: Compositional matrix adjust.
 Identities = 28/83 (33%), Positives = 41/83 (49%)
 Frame = +1

Query: 374 GMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPE 433
           G+ Y+     IHRD+++ NIL+ N    K+ADFG+A  + D           P  W APE
Sbjct: 94  GL*YLHSRRKIHRDIKAGNILLNNEGHAKLADFGVAGQLTDTMAKRNTVIGTP-YWMAPE 270

Query: 434 AALYGRFTIKSDVWSFGILLTEL 456
                 +   +D+WS GI   E+
Sbjct: 271 VIQEIGYDCVADIWSLGITALEM 339
>15910
          Length = 1361

 Score = 47.8 bits (112), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 34/114 (29%), Positives = 57/114 (50%), Gaps = 3/114 (2%)
 Frame = +2

Query: 369 AQVAAGMAYIERMNYIHRDLRSANIL---VGNGLICKIADFGLARLIEDNEYTARQGAKF 425
           + +  G+ YI     +HRDL+  N+L   + +    K+ADFGL+R+IE  E         
Sbjct: 485 SDILHGVQYIHANGVVHRDLKPENLLYECMTDDSKLKLADFGLSRIIEP-EVQMSTVCGT 661

Query: 426 PIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERG 479
           P  + APE     ++T   D+WS G++   L+  G  P+   N  E+  ++ +G
Sbjct: 662 P-GYCAPEVLKGDKYTPSVDMWSVGVIAYILLC-GYEPFFAENEFEMYRKIIKG 817
>30755
          Length = 1137

 Score = 47.4 bits (111), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 37/142 (26%), Positives = 66/142 (46%), Gaps = 2/142 (1%)
 Frame = +2

Query: 368 AAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEY--TARQGAKF 425
            A++ + + Y+     I+RDL+  N+L+      K+ADFGL +  ED  Y  T +     
Sbjct: 50  GAEIISALGYLHSQGIIYRDLKLENLLLDKDGHIKVADFGLCK--EDITYGRTTKTFCGT 223

Query: 426 PIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCP 485
           P ++ APE      +    D W  G+++ E++  GR+P+    + +VL  +     +  P
Sbjct: 224 P-EYLAPEVLDDNDYGRAVDWWGTGVVMYEMIC-GRLPFYN-RDHDVLFTLILVEDVKFP 394

Query: 486 QDCPISLHELMIHCWKKDPEER 507
           ++       L+     KDP  R
Sbjct: 395 RNITDEAKSLLSGLLAKDPRNR 460
>26560
          Length = 398

 Score = 46.2 bits (108), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 32/103 (31%), Positives = 52/103 (50%), Gaps = 1/103 (0%)
 Frame = -1

Query: 368 AAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPI 427
           AA+V  G+ ++     ++RDL+ ANIL+      +I+D GLA         A  G     
Sbjct: 338 AAEVMLGLEHMHSRFVVYRDLKPANILLDENGHVRISDLGLACDFSKKRPHASVGTH--- 168

Query: 428 KWTAPEAALYGR-FTIKSDVWSFGILLTELVTKGRVPYPGMNN 469
            + APE  + G+ +   +D +SFG +L +L+ KG  P+   N 
Sbjct: 167 GYMAPEVLMKGQSYDSSADWFSFGCMLYKLL-KGHSPFRQHNQ 42
>21210
          Length = 518

 Score = 45.8 bits (107), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 34/86 (39%), Positives = 47/86 (54%), Gaps = 4/86 (4%)
 Frame = +3

Query: 432 PEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPG-MNNREVLEQVERGYRMPC-PQDCP 489
           P A+ +G + ++SDVWS GI L EL T GR PY   ++  + L+QV RG   PC P D  
Sbjct: 42  PRASSHG-YDVRSDVWSLGITLMELAT-GRFPYRKWVSIFDQLQQVVRGV-APCLPHDGA 212

Query: 490 IS--LHELMIHCWKKDPEERPTFEYL 513
            S      +  C  KD ++RP +  L
Sbjct: 213 FSHDFVNFVNKCLTKDEKQRPKYNKL 290
>19761
          Length = 473

 Score = 45.1 bits (105), Expect = 8e-05,   Method: Compositional matrix adjust.
 Identities = 34/119 (28%), Positives = 54/119 (45%), Gaps = 3/119 (2%)
 Frame = -3

Query: 370 QVAAGMAYIERMN--YIHRDLRSANILVGNGLICKIADFGLAR-LIEDNEYTARQGAKFP 426
           Q A+ + Y+       +HRDL+  NI V      ++ D GLAR L    ++   Q     
Sbjct: 399 QTASALNYMHTHTPVILHRDLKPQNIYVTEKGDVRLGDLGLARKLTGPADFATSQVGT-- 226

Query: 427 IKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCP 485
           I + +PE      +  KSD+WS G +  ++   G+     M    +L QV  G ++P P
Sbjct: 225 IMYLSPEILSQQPYNSKSDIWSLGCVFYDIT--GKKGSDEMGVMFLLVQVMGGRKLPLP 55
>29687
          Length = 434

 Score = 45.1 bits (105), Expect = 8e-05,   Method: Compositional matrix adjust.
 Identities = 22/55 (40%), Positives = 32/55 (58%)
 Frame = -2

Query: 89  ALYDYEARTEDDLSFHKGEKFQILNSSEGDWWEARSLTTGETGYIPSNYVAPVDS 143
           AL+DY A+ ED+LSF KG     ++  +G WW      T +  + PSNYV  +D+
Sbjct: 286 ALHDYNAKREDELSFCKGAIITNVSRQDGGWWRG-DYGTKKQHWFPSNYVEEIDT 125
>11185
          Length = 473

 Score = 44.3 bits (103), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 35/145 (24%), Positives = 63/145 (43%), Gaps = 25/145 (17%)
 Frame = +1

Query: 363 NLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYT---- 418
           ++ D    +  G+ YI  +  +  DLR + +L+    + K ADFGL+++  +N       
Sbjct: 4   SIRDFGIHLVTGLHYIHSLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFK 183

Query: 419 -ARQGAKFPIK----------------WTAPEAALYGRFTIKSDVWSFGILLTELVTKGR 461
            A  G ++ I+                + APE       +I SD+W+ G +  E+ +  R
Sbjct: 184 FAEAGDQWNIQSAEEMMKQVPTSGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFSGSR 363

Query: 462 V---PYPG-MNNREVLEQVERGYRM 482
           +   P P  +N  E L Q +   R+
Sbjct: 364 LSAKPSPEFLNLLESLLQKDSTRRL 438
>14257
          Length = 919

 Score = 44.3 bits (103), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 28/89 (31%), Positives = 47/89 (52%)
 Frame = -3

Query: 147 EEWYFGKLGRKDAERQLLSFGNPRGTFLIRESETTKGAYSLSIRDWDDMKGDHVKHYKIR 206
           EEWY GK+GRK+AE+ L       G FL+RE+  +   + LS R     +  +V+H  + 
Sbjct: 896 EEWYHGKIGRKEAEKLL----ELDGDFLVREASNSAAQFVLSGR-----QNGNVRHLLL- 747

Query: 207 KLDNGGYYITTRAQFETLQQLVQHYSEKA 235
            +D  G   T    F+++  L+ ++ + A
Sbjct: 746 -VDPDGIVRTKDFIFDSVSHLINYHRQNA 663
>01106
          Length = 878

 Score = 43.5 bits (101), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 36/139 (25%), Positives = 67/139 (48%), Gaps = 15/139 (10%)
 Frame = +3

Query: 272 KKLGQGCFAEVWLGTWNGNTK--VAIKTLKPGTMSPESFLEEAQIMKKLKHD-------- 321
           +KLG G F+ VWL  W+   K  VA+K +K      E+ L+E +++K ++          
Sbjct: 336 RKLGWGHFSTVWL-CWDLTCKRFVALKVVKSAQHYTETALDEVKLLKCVRESDVADPARA 512

Query: 322 KLVQL---YAVVSEEPIYIVTEYMSKG-SLLDFLKDGEGRALKLPNLVDMAAQVAAGMAY 377
           K VQL   + +      ++   +   G +LL  +     + + + N+  +  QV  G++Y
Sbjct: 513 KCVQLLDDFKISGVNGTHVAMVFEVLGYNLLKLIIRSNYQGIPIHNVKLIIRQVLEGLSY 692

Query: 378 IE-RMNYIHRDLRSANILV 395
           +  +   IH D++  NIL+
Sbjct: 693 MHAKCRIIHTDIKPENILI 749
>28638
          Length = 1458

 Score = 42.0 bits (97), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 35/109 (32%), Positives = 53/109 (48%), Gaps = 5/109 (4%)
 Frame = -1

Query: 355 EGRALKLPNLVDMAAQVAAGMAYIE--RMNYIHRDLRSANILVGN---GLICKIADFGLA 409
           EG +L L      A Q+   + ++    MN IH DL+  NIL+ N     I KI DFG +
Sbjct: 852 EGVSLNLTR--KFAQQLCTALLFLATPEMNIIHCDLKPENILLCNPKRSAI-KIVDFGSS 682

Query: 410 RLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVT 458
             +    Y   Q ++F   + +PE  L   + +  D+WS G +L E+ T
Sbjct: 681 CQLGQRIYQYIQ-SRF---YRSPEVLLGVPYDLAIDMWSLGCILVEMHT 547
>28095
          Length = 597

 Score = 41.6 bits (96), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 19/54 (35%), Positives = 30/54 (55%)
 Frame = +3

Query: 89  ALYDYEARTEDDLSFHKGEKFQILNSSEGDWWEARSLTTGETGYIPSNYVAPVD 142
           A+YDY+A   D++SF+ G+        +  W   R   TG+ G +PSNYV  ++
Sbjct: 270 AMYDYQAADSDEVSFNDGDTIIECQPVDAGWMTGRVERTGQYGMLPSNYVERIN 431
>12786
          Length = 460

 Score = 41.2 bits (95), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 27/107 (25%), Positives = 51/107 (47%), Gaps = 21/107 (19%)
 Frame = -3

Query: 384 IHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPI-KWTAPEAALYG---- 438
           IH DL+ AN ++  G + K+ DFG+A  ++ ++ +  + ++     + +PEA +      
Sbjct: 344 IHSDLKPANFMLVAGNL-KLIDFGIANTLQQDKTSVLKDSRVGTPSYMSPEAIMAACDDS 168

Query: 439 ----------------RFTIKSDVWSFGILLTELVTKGRVPYPGMNN 469
                           +  ++SDVWS G +L  +V  GR P+  + N
Sbjct: 167 ADDSMEEDGHRTKPKYKVGVRSDVWSLGCILYNMVY-GRTPFQHIKN 30
>05206
          Length = 1075

 Score = 41.2 bits (95), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 19/50 (38%), Positives = 27/50 (54%)
 Frame = +1

Query: 89  ALYDYEARTEDDLSFHKGEKFQILNSSEGDWWEARSLTTGETGYIPSNYV 138
           ALY +EA  E  +   + E+ QIL   +GD W       G  G++PS+YV
Sbjct: 103 ALYPFEAMNEGSVPMGENEEMQILEEDQGDGWTRVRKADGSEGFVPSSYV 252
>26711
          Length = 405

 Score = 41.2 bits (95), Expect = 0.001,   Method: Composition-based stats.
 Identities = 31/111 (27%), Positives = 54/111 (48%), Gaps = 3/111 (2%)
 Frame = -2

Query: 370 QVAAGMAYIERMNYIHRDLRSANILVGNGLI--CKIADFGLAR-LIEDNEYTARQGAKFP 426
           QV   + ++     +H DL+ +N+L+    +   ++ DFGLAR L    E     G    
Sbjct: 392 QVLDILQHVHAQGVVHMDLKPSNLLLSGDKLDSVQLIDFGLARKLYPPQETFLNHGTP-- 219

Query: 427 IKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVE 477
             +T+PEA      +  SDVW  G+L   L++ G+ P+   +  E L++ +
Sbjct: 218 -GFTSPEALDVKPISTASDVWGVGVLAYILLS-GQSPFQADSATESLKKTQ 72
>37602
          Length = 804

 Score = 40.8 bits (94), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 23/77 (29%), Positives = 37/77 (48%)
 Frame = -1

Query: 330 VSEEPIYIVTEYMSKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLR 389
           +  E ++I  EY   GS+ D         L  P +  +  +   G+ Y+ R   +HRD++
Sbjct: 309 LRREKLWIAMEYCGGGSMQDIYH--VTGPLTEPQIAFVCRETLKGLHYLHRRGKMHRDIK 136

Query: 390 SANILVGNGLICKIADF 406
            ANIL+      K+ADF
Sbjct: 135 GANILLTEEGDVKLADF 85
>01494
          Length = 2122

 Score = 40.4 bits (93), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 30/107 (28%), Positives = 49/107 (45%), Gaps = 5/107 (4%)
 Frame = +3

Query: 89  ALYDYEARTEDDLSFHKGEKFQILNSSEGDWWEARSLTTGETGYIPSNYVAPVDS---IQ 145
           AL+DY A  +D+LSF KG     ++  +G WW        +  + PSN+V  +++   + 
Sbjct: 318 ALHDYNANRDDELSFCKGAIITNVSRQDGGWWRG-DYGAKKQHWFPSNFVEEIETHSDVN 494

Query: 146 AEEWYFGKL--GRKDAERQLLSFGNPRGTFLIRESETTKGAYSLSIR 190
           ++    G L  G  D +  L+    PRG          K A+ +S R
Sbjct: 495 SDSMPLGSLQQGSFDIQGCLVEPLAPRG---------DKSAFRISTR 608
>18481
          Length = 437

 Score = 40.0 bits (92), Expect = 0.003,   Method: Composition-based stats.
 Identities = 21/65 (32%), Positives = 37/65 (56%), Gaps = 3/65 (4%)
 Frame = -1

Query: 357 RALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICK---IADFGLARLIE 413
           R   L  ++ ++ Q+ + + +I +  +IHRDL+  N L+G G  C    I DFGL++  +
Sbjct: 212 RRFTLKTILMVSDQLLSRLEFIHQKCFIHRDLKPDNFLMGLGRHCHRLYIIDFGLSKRYK 33

Query: 414 DNEYT 418
           D + T
Sbjct: 32  DTQGT 18
>32000
          Length = 644

 Score = 39.7 bits (91), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 29/85 (34%), Positives = 45/85 (52%), Gaps = 3/85 (3%)
 Frame = -1

Query: 402 KIADFGLARL--IEDNEYTARQGAKFPIKWTAPEAALYGRF-TIKSDVWSFGILLTELVT 458
           KIADFGLAR+  +    YT        + + APE  L  RF ++  D+WS G +  E++T
Sbjct: 569 KIADFGLARVFGLPVRTYTHEVIT---LWYRAPEILLGCRFYSVPVDIWSLGCIFVEMMT 399

Query: 459 KGRVPYPGMNNREVLEQVERGYRMP 483
           + R  +PG +  + L ++ R    P
Sbjct: 398 R-RALFPGDSEIDQLYRIFRTLGTP 327
>16708
          Length = 1397

 Score = 38.9 bits (89), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 35/149 (23%), Positives = 74/149 (49%), Gaps = 11/149 (7%)
 Frame = -1

Query: 274  LGQGCFAEVWLG-TWNGNTKVAIKTLKPGTMSPESFLEEAQIMKKLKHD-KLVQLY-AVV 330
            LG+G F +V+     + + K A+KT    ++     L+E + + +++    L Q++ A V
Sbjct: 1379 LGKGVFGKVYEARLLSTHEKAALKT----SILCHHSLDEVEALGRIEGGFYLAQMFGAWV 1212

Query: 331  SEEP---IYIVTEYMSKGSLLDFLKDGEGRALKL----PNLVD-MAAQVAAGMAYIERMN 382
            +  P   + I+  +   G L +     + + + +    P +V  +A Q    + +I  + 
Sbjct: 1211 TCLPFPKMNILLHFYEMGPLCNVYAHYKNKEMPIRWSNPAMVCCIAGQXVCALEHIHELG 1032

Query: 383  YIHRDLRSANILVGNGLICKIADFGLARL 411
             +H D+++ N+LV     CK+ D+G+A+L
Sbjct: 1031 VVHMDVKADNVLVDAHGNCKLTDYGIAQL 945
>32264
          Length = 287

 Score = 38.5 bits (88), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 18/44 (40%), Positives = 28/44 (63%)
 Frame = +1

Query: 476 VERGYRMPCPQDCPISLHELMIHCWKKDPEERPTFEYLQGFLED 519
           +E GYR+      P S+++LM+ CW+  PE+RP F+ L   L+D
Sbjct: 1   IEDGYRLQQNPQTPDSVYKLMLRCWEYVPEKRPHFKELYTSLKD 132
>35671
          Length = 567

 Score = 38.5 bits (88), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 15/47 (31%), Positives = 28/47 (59%)
 Frame = -3

Query: 477 ERGYRMPCPQDCPISLHELMIHCWKKDPEERPTFEYLQGFLEDYFTA 523
           ++G R+  P  C    +++M+ CW +  EERPTF+ L   +E+ + +
Sbjct: 565 QKGNRLAKPISCTDEAYKVMLQCWTESREERPTFKKLVPVMENLYRS 425
>17286
          Length = 489

 Score = 37.7 bits (86), Expect = 0.012,   Method: Compositional matrix adjust.
 Identities = 17/56 (30%), Positives = 31/56 (55%)
 Frame = +3

Query: 89  ALYDYEARTEDDLSFHKGEKFQILNSSEGDWWEARSLTTGETGYIPSNYVAPVDSI 144
           A+YD+   ++ +L F +G+   +++  + +W+E      G+ GY P NYV  V  I
Sbjct: 36  AIYDFLPESDGELGFQEGDMITLISQVDENWFEGS--VHGKVGYFPINYVEVVVPI 197
>16716
          Length = 934

 Score = 37.4 bits (85), Expect = 0.014,   Method: Compositional matrix adjust.
 Identities = 28/111 (25%), Positives = 44/111 (39%)
 Frame = -1

Query: 28  YRYGTDPTPQHYPSFGVTSIPNYNNFHAAGGQGLTVFGGVNSSSHXXXXXXXXXXXXXXF 87
           Y    +P PQH P      + +      A  Q     GG +++                 
Sbjct: 577 YEVSEEPAPQHEPEESPYEMADEEPAAPAQSQP----GGGSTA----------------- 461

Query: 88  VALYDYEARTEDDLSFHKGEKFQILNSSEGDWWEARSLTTGETGYIPSNYV 138
           +ALYDY+A  +D+L+F   +    +   +  WW  R    G+ G  P+NYV
Sbjct: 460 IALYDYQAADDDELTFDPDDVITDIEMIDDGWW--RGSCHGKNGLFPANYV 314
>30740
          Length = 488

 Score = 37.4 bits (85), Expect = 0.017,   Method: Compositional matrix adjust.
 Identities = 13/33 (39%), Positives = 21/33 (63%)
 Frame = +2

Query: 91  YDYEARTEDDLSFHKGEKFQILNSSEGDWWEAR 123
           YD+  R  +DL F KG+  ++++  E +WW AR
Sbjct: 203 YDFSGRDPEDLPFSKGDILELISKDEEEWWTAR 301
>00394
          Length = 548

 Score = 37.0 bits (84), Expect = 0.019,   Method: Compositional matrix adjust.
 Identities = 30/100 (30%), Positives = 53/100 (53%), Gaps = 13/100 (13%)
 Frame = -2

Query: 266 DSLFL--EKKLGQGCFAEVWLGTWNGNTKVAI-----KTLKPGTMSPESFLEEAQIMKKL 318
           D+ FL  +K++G+G F  V+ G  +    VA+     +  K      + F EEA+++K+L
Sbjct: 304 DNRFLKFDKEIGRGSFKTVYKGL-DTELGVAVAWCELQDKKWNKAERQRFKEEAEMLKEL 128

Query: 319 KHDKLVQLYAVVSE------EPIYIVTEYMSKGSLLDFLK 352
           +H  +V+ +    E      + I +VTE M+ G+L  +LK
Sbjct: 127 QHPNIVRFFDYWEEHNHRNRKVIILVTELMTSGTLKTYLK 8
>38046
          Length = 446

 Score = 36.6 bits (83), Expect = 0.023,   Method: Composition-based stats.
 Identities = 15/26 (57%), Positives = 20/26 (76%)
 Frame = -1

Query: 371 VAAGMAYIERMNYIHRDLRSANILVG 396
           +A  MAY+E+ N+IHR+L   NILVG
Sbjct: 98  IADAMAYMEKENFIHRNLGDRNILVG 21
>27405
          Length = 532

 Score = 36.2 bits (82), Expect = 0.034,   Method: Compositional matrix adjust.
 Identities = 24/80 (30%), Positives = 38/80 (47%)
 Frame = -3

Query: 368 AAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPI 427
           AA+V  G+ ++     ++RDL+ ANIL+      +I+D GLA      +  A  G     
Sbjct: 236 AAEVMLGLEHMHSRFVVYRDLKPANILLDENGHVRISDLGLACDFSKKKPHASVGTH--- 66

Query: 428 KWTAPEAALYGRFTIKSDVW 447
            + APE  + G+    S  W
Sbjct: 65  GYMAPEVLMKGQAYDSSADW 6
>06462
          Length = 1511

 Score = 36.2 bits (82), Expect = 0.036,   Method: Compositional matrix adjust.
 Identities = 27/99 (27%), Positives = 43/99 (43%)
 Frame = +1

Query: 133  IPSNYVAPVDSIQAEEWYFGKLGRKDAERQLLSFGNPRGTFLIRESETTKGAYSLSIRDW 192
            +PS+     D    E WY GK+ R++AE+ L       G FL+RES      + LS +  
Sbjct: 1048 MPSSETGVTDPPLHELWYHGKMSRREAEKLL----GKDGDFLVRESGHNXSQFVLSGK-- 1209

Query: 193  DDMKGDHVKHYKIRKLDNGGYYITTRAQFETLQQLVQHY 231
                  H +   +  +D  G   T    F+ +  LV ++
Sbjct: 1210 -----HHGQFIHLLLVDPDGIVRTKDYIFDNISHLVSYH 1311
>31789
          Length = 676

 Score = 36.2 bits (82), Expect = 0.038,   Method: Compositional matrix adjust.
 Identities = 33/123 (26%), Positives = 61/123 (49%), Gaps = 13/123 (10%)
 Frame = +2

Query: 266 DSLFL--EKKLGQGCFAEVWLGTWNGNTKVAI-----KTLKPGTMSPESFLEEAQIMKKL 318
           D+ FL  + ++G+G F  V+ G  +    VA+     +  K      + F EEA+++K+L
Sbjct: 314 DNRFLKFDVEIGRGSFKTVYKGL-DTELGVAVAWCELQDKKWNKTERQRFKEEAEMLKEL 490

Query: 319 KHDKLVQLYAVVSE------EPIYIVTEYMSKGSLLDFLKDGEGRALKLPNLVDMAAQVA 372
           +H  +V+ +    E      + I +VTE M+ G+L  +LK    + + L  L +   Q+ 
Sbjct: 491 QHPNIVRFFDYWEEHNHRNRKVIILVTELMTSGTLKTYLK--RFKKINLKVLKNWCRQIL 664

Query: 373 AGM 375
            G+
Sbjct: 665 KGL 673
>21433
          Length = 590

 Score = 35.8 bits (81), Expect = 0.045,   Method: Compositional matrix adjust.
 Identities = 25/89 (28%), Positives = 40/89 (44%)
 Frame = +2

Query: 370 QVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKW 429
           Q+++ + Y      IHRD++  N+L+G     KIADFG +     +  T   G    + +
Sbjct: 191 QLSSALEYCHYRKVIHRDIKPENLLLGLKGDLKIADFGWSVHAPSSRRTTMCGT---LDY 361

Query: 430 TAPEAALYGRFTIKSDVWSFGILLTELVT 458
             PE           D+WS G+L  E + 
Sbjct: 362 LPPEMVEGKTHDENVDLWSLGVLCYEFLV 448
>01392
          Length = 1806

 Score = 35.8 bits (81), Expect = 0.050,   Method: Compositional matrix adjust.
 Identities = 32/109 (29%), Positives = 51/109 (46%), Gaps = 12/109 (11%)
 Frame = -1

Query: 370  QVAAGMAYIERMNYIHRDLRSANIL---VGNGLICKIADFGLARLIE-DNEYTARQGAKF 425
             +A  + ++      HRDL+  NIL   + + +  KI DF LA  I  D + T       
Sbjct: 1767 HIARALDFLHSKGIAHRDLKPENILCEHLDDVVPVKICDFDLASGISCDGDGTKTPELLT 1588

Query: 426  PI---KWTAPEA--ALYG---RFTIKSDVWSFGILLTELVTKGRVPYPG 466
            P+   ++ APE   A  G    +  + D+WS GI+L  ++  G  P+ G
Sbjct: 1587 PVGSAEYMAPEVVDAWVGDSFSYDKRCDLWSLGIILYIMLC-GYPPFYG 1444
>18881
          Length = 762

 Score = 35.4 bits (80), Expect = 0.054,   Method: Compositional matrix adjust.
 Identities = 22/67 (32%), Positives = 35/67 (52%), Gaps = 2/67 (2%)
 Frame = -3

Query: 169 PRGTFLIRESETTKGAYSLSIRDWDDMK--GDHVKHYKIRKLDNGGYYITTRAQFETLQQ 226
           P GTFLIR + T       S R+        + V+H K+ +   G +Y+     F+++QQ
Sbjct: 748 PDGTFLIRVTNT-------SARESCPQY*YANAVRHIKVNRNPQGRFYLADGHYFDSVQQ 590

Query: 227 LVQHYSE 233
           LV+HY +
Sbjct: 589 LVEHYEK 569

 Score = 28.9 bits (63), Expect = 6.0,   Method: Compositional matrix adjust.
 Identities = 14/45 (31%), Positives = 22/45 (48%), Gaps = 2/45 (4%)
 Frame = -3

Query: 101 LSFHKGEKFQIL--NSSEGDWWEARSLTTGETGYIPSNYVAPVDS 143
           ++    ++  IL  N  +  WW+  +L T + GY P  YV   DS
Sbjct: 436 VTLKLNDRISILSKNGQDKGWWKGENLRTKKVGYFPLAYVDEEDS 302
>07933
          Length = 728

 Score = 35.0 bits (79), Expect = 0.069,   Method: Compositional matrix adjust.
 Identities = 13/30 (43%), Positives = 18/30 (60%)
 Frame = +3

Query: 485 PQDCPISLHELMIHCWKKDPEERPTFEYLQ 514
           P  CP  L+ +M+ CW  +P  RPTF  L+
Sbjct: 3   PNYCPNLLYNIMMQCWSAEPSARPTFHKLE 92
>13664
          Length = 507

 Score = 35.0 bits (79), Expect = 0.073,   Method: Compositional matrix adjust.
 Identities = 16/45 (35%), Positives = 25/45 (55%)
 Frame = +2

Query: 88  VALYDYEARTEDDLSFHKGEKFQILNSSEGDWWEARSLTTGETGY 132
           VALYDY+A+  D+L+   G+   +L+     WW    L  G+ G+
Sbjct: 374 VALYDYKAQRSDELTILSGDVIMLLHKDSESWWMGE-LLDGQQGF 505
>29360
          Length = 363

 Score = 34.3 bits (77), Expect = 0.13,   Method: Composition-based stats.
 Identities = 28/116 (24%), Positives = 50/116 (43%), Gaps = 7/116 (6%)
 Frame = +3

Query: 287 WNGNTK--VAIKTLKPGTMSPESFLEEAQIMKKLKHD-----KLVQLYAVVSEEPIYIVT 339
           W   T   VAIK LK           E  I+++L  +       V+ +     +    + 
Sbjct: 12  WKKGTSEIVAIKILKNHPSYARQGQIEVSILQRLSQESADDYNFVRAFECFQHKNHTCLV 191

Query: 340 EYMSKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILV 395
             M + +L DFLK  + + L L  +  +  QV   +  ++++  IH DL+  NI++
Sbjct: 192 FEMLEQNLYDFLKQNKFQPLPLKYIRPITQQVLTALRKLKQLGLIHADLKPENIML 359
>02638
          Length = 1490

 Score = 34.3 bits (77), Expect = 0.14,   Method: Compositional matrix adjust.
 Identities = 25/103 (24%), Positives = 49/103 (47%), Gaps = 7/103 (6%)
 Frame = +1

Query: 427 IKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRM---- 482
           I + APE      +    DVWS G ++ E+ T  R P+   N+ ++   +   +++    
Sbjct: 28  IAFMAPEVLRGESYGRACDVWSVGCVMIEMCT-CRPPW---NSHDISNHLALIFKIASSV 195

Query: 483 ---PCPQDCPISLHELMIHCWKKDPEERPTFEYLQGFLEDYFT 522
              P P++    + +LM+ C ++D + RP+ + L   +   FT
Sbjct: 196 DPPPIPENMSPPVRDLMLRCLEQDSDFRPSAKDL--LMHPLFT 318
>37260
          Length = 401

 Score = 33.5 bits (75), Expect = 0.20,   Method: Composition-based stats.
 Identities = 17/56 (30%), Positives = 30/56 (53%)
 Frame = -1

Query: 149 WYFGKLGRKDAERQLLSFGNPRGTFLIRESETTKGAYSLSIRDWDDMKGDHVKHYK 204
           WY+G L  ++AE +L+      G+FL+R+S       SLS +    +    ++H+K
Sbjct: 182 WYWGPLSYEEAESKLMD--KRDGSFLVRDSSNENYILSLSFKSMGHVHHTRIEHHK 21
>18401
          Length = 463

 Score = 31.2 bits (69), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 21/59 (35%), Positives = 30/59 (50%), Gaps = 5/59 (8%)
 Frame = -3

Query: 429 WTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVER-----GYRM 482
           + APE  L   ++   DVWS G ++ EL T G   +   +N+E L  +ER      YRM
Sbjct: 434 YRAPEVILELGWSHPCDVWSVGCIMFELYT-GYTLFQTHDNKEHLAMMERILGSLPYRM 261
>13641
          Length = 2081

 Score = 30.8 bits (68), Expect = 1.4,   Method: Compositional matrix adjust.
 Identities = 15/58 (25%), Positives = 28/58 (48%), Gaps = 9/58 (15%)
 Frame = +2

Query: 89  ALYDYEARTEDD-------LSFHKGEKFQILNSSEGDWWEA--RSLTTGETGYIPSNY 137
           A++ + ++ +D+       LSF +G+   I+N  +  WW+A          G IPS +
Sbjct: 164 AMFSFNSKLDDNIPCKEAGLSFQQGDILHIVNQEDAIWWQAYKHGDAKKRAGLIPSRH 337
>36481
          Length = 806

 Score = 30.8 bits (68), Expect = 1.4,   Method: Compositional matrix adjust.
 Identities = 42/175 (24%), Positives = 70/175 (40%), Gaps = 12/175 (6%)
 Frame = +2

Query: 232 SEKADGLCFNLTVVSSSCTPQTSGLAKDAWEVAR-----DSLFLEKKLGQGCFAEV-WLG 285
           S +ADG   N TV           + KD W   R     + + L    G+G F +V    
Sbjct: 269 SLRADGRLKNRTV--------WMMMRKDIWCTMRGTSSTNDMKLCPHWGEGTFGKVVQCK 424

Query: 286 TWNGNTKVAIKTLKPGTMSPESFLEEAQIMKKLK----HDK--LVQLYAVVSEEPIYIVT 339
                  +A+K +K      E+   E  +++KL+    H K   VQ+           ++
Sbjct: 425 DLLKGDDIALKIIKNVDKYREAAKLEINVLEKLREKDPHAKHMCVQMLDWFDYHGHVCIS 604

Query: 340 EYMSKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANIL 394
            +M   S+ DFLKD    A  +  +  ++ Q+   + ++      H DL+  NIL
Sbjct: 605 FHMLGLSVFDFLKDNSYGAYPIEQVRHISYQLCYAVNFLHENQLTHTDLKPENIL 769
>23319
          Length = 2235

 Score = 30.8 bits (68), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 12/45 (26%), Positives = 24/45 (53%)
 Frame = +3

Query: 432 PEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQV 476
           P+      ++   D+WS G +  EL   GR  +PG ++ + L+++
Sbjct: 3   PDVYXAKMYSTSIDMWSAGCIFAELANAGRPLFPGNDDDDQLKRI 137
>27287
          Length = 514

 Score = 30.4 bits (67), Expect = 1.7,   Method: Compositional matrix adjust.
 Identities = 11/30 (36%), Positives = 19/30 (63%)
 Frame = -2

Query: 495 LMIHCWKKDPEERPTFEYLQGFLEDYFTAT 524
           +M  CW++DP +RP+F  L   L+   T++
Sbjct: 474 IMHSCWQEDPNDRPSFSRLVQELDKMLTSS 385
>29590
          Length = 320

 Score = 30.0 bits (66), Expect = 2.4,   Method: Composition-based stats.
 Identities = 13/43 (30%), Positives = 26/43 (60%)
 Frame = +3

Query: 429 WTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNRE 471
           + APE   Y   +I++D+WS G+L   ++T    P+ G+ +++
Sbjct: 72  YVAPEVLDYEPLSIQTDMWSLGVLSYVMLTACS-PFVGITSKK 197
>18680
          Length = 451

 Score = 29.6 bits (65), Expect = 2.9,   Method: Composition-based stats.
 Identities = 14/36 (38%), Positives = 20/36 (55%)
 Frame = +1

Query: 483 PCPQDCPISLHELMIHCWKKDPEERPTFEYLQGFLE 518
           PC   C ++ + +M  C+K  P  RP F+ LQG  E
Sbjct: 280 PC---CSVNSYCIM*FCFKLTPTSRPQFQPLQGV*E 378
>27568
          Length = 505

 Score = 28.9 bits (63), Expect = 5.4,   Method: Composition-based stats.
 Identities = 13/34 (38%), Positives = 20/34 (58%), Gaps = 3/34 (8%)
 Frame = +1

Query: 231 YSEKADGLCFNLTVVSSS---CTPQTSGLAKDAW 261
           YS+K  GLC ++ V S+    CTP  +   ++AW
Sbjct: 4   YSQKVSGLCGSVCVASNQTIVCTPCRTRHTREAW 105
>27562
          Length = 399

 Score = 28.9 bits (63), Expect = 5.5,   Method: Composition-based stats.
 Identities = 18/54 (33%), Positives = 26/54 (48%), Gaps = 3/54 (5%)
 Frame = -1

Query: 470 REVLEQVERGYRMPCPQDCPISLHELMIH-CWKKDPEERPT--FEYLQGFLEDY 520
           R +  Q+ R      P+ C  SL E++    WKKDP ER     E L  F++ +
Sbjct: 222 RVLWTQMRRRGTQIQPRPCSSSLFEIL*ETAWKKDPSERTENDIEILMDFMQHF 61
>18663
          Length = 600

 Score = 28.5 bits (62), Expect = 7.9,   Method: Compositional matrix adjust.
 Identities = 21/88 (23%), Positives = 36/88 (40%), Gaps = 8/88 (9%)
 Frame = +2

Query: 428 KWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPY--------PGMNNREVLEQVERG 479
            + APE      +    D W+ G+LL E++  GR P+        P  N  + L QV   
Sbjct: 23  NYIAPEILRGEDYGFSVDWWALGVLLYEMLA-GRSPFDIAGASENPDQNTEDYLFQVILE 199

Query: 480 YRMPCPQDCPISLHELMIHCWKKDPEER 507
             +  P+   +    ++     K+P +R
Sbjct: 200 KTIRIPRSLSVKAASVLKGFLNKNPADR 283
>15741
          Length = 402

 Score = 28.5 bits (62), Expect = 8.0,   Method: Composition-based stats.
 Identities = 11/32 (34%), Positives = 18/32 (56%)
 Frame = -3

Query: 363 NLVDMAAQVAAGMAYIERMNYIHRDLRSANIL 394
           +    A  VA GMA++     +HRD+ + N+L
Sbjct: 97  DFFSFALHVARGMAHVANNKIVHRDVAARNVL 2
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31543974|ref|NP_061223.2| tyrosine
3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta
polypeptide [Mus musculus]
         (246 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

12344                                                                 318   1e-87
13465                                                                 177   3e-45
33715                                                                 176   7e-45
17028                                                                 141   2e-34
15092                                                                 129   2e-30
27988                                                                  70   2e-20
03892                                                                  27   7.7  
>12344
          Length = 1658

 Score =  318 bits (816), Expect = 1e-87,   Method: Compositional matrix adjust.
 Identities = 154/237 (64%), Positives = 190/237 (80%)
 Frame = +2

Query: 4   DKSELVQKAKLAEQAERYDDMAAAMKAVTEQGHELSNEERNLLSVAYKNVVGARRSSWRV 63
           D+ + V +AK   +AERYD+M   MK V     EL+ EERNLLSVAYKNV+GARR+SWR+
Sbjct: 62  DREDQVYQAKQLNRAERYDEMVKFMKIVACMDVELTVEERNLLSVAYKNVIGARRASWRI 241

Query: 64  ISSIEQKTERNEKKQQMGKEYREKIEAELQDICNDVLELLDKYLILNATQAESKVFYLKM 123
           +SS+EQK ++ E K+ + KEYR KIE EL+DIC DVL++L+K+LI+NA   ESKVFY KM
Sbjct: 242 VSSLEQKEDKCEDKKAINKEYRMKIEKELKDICEDVLDILEKHLIVNANTGESKVFYYKM 421

Query: 124 KGDYFRYLSEVASGENKQTTVSNSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYEI 183
           KGDY RYL+E A G +++    NS  AY+ A +I+  E+ PTHPIRLGLALNFSVFYYEI
Sbjct: 422 KGDYHRYLAEFAVGNDRKEAAENSLVAYKAASDIAMIELAPTHPIRLGLALNFSVFYYEI 601

Query: 184 LNSPEKACSLAKTAFDEAIAELDTLNEESYKDSTLIMQLLRDNLTLWTSENQGDEGD 240
           LNSP++AC LAK AFD+AIAELDTL+EESYKDSTLIMQLLRDNLTLWTS+ QG+ G+
Sbjct: 602 LNSPDRACRLAKAAFDDAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSDMQGEGGE 772
>13465
          Length = 596

 Score =  177 bits (449), Expect = 3e-45,   Method: Compositional matrix adjust.
 Identities = 85/151 (56%), Positives = 116/151 (76%), Gaps = 2/151 (1%)
 Frame = +2

Query: 4   DKSELVQKAKLAEQAERYDDMAAAMKAVTEQGHELSNEERNLLSVAYKNVVGARRSSWRV 63
           D+ + V +AKLAEQAERYD+M  AMK V   G++L+ EERNLLSVAYKNV+GARR+SWR+
Sbjct: 116 DRDDFVYQAKLAEQAERYDEMVEAMKKVASMGNDLTVEERNLLSVAYKNVIGARRASWRI 295

Query: 64  ISSIEQK--TERNEKKQQMGKEYREKIEAELQDICNDVLELLDKYLILNATQAESKVFYL 121
           +SS+EQK   + +  K +M K YR++IE EL+ IC DVL+++D +LI + TQ ESKVFY 
Sbjct: 296 VSSVEQKDLDKPDPDKGKMTKGYRQQIETELKQICEDVLKIIDDHLIPSTTQGESKVFYY 475

Query: 122 KMKGDYFRYLSEVASGENKQTTVSNSQQAYQ 152
           KMKGDY+RYL+E A+G+ ++    +S  AY+
Sbjct: 476 KMKGDYYRYLAEFATGDPRKEAAESSLVAYK 568
>33715
          Length = 434

 Score =  176 bits (447), Expect = 7e-45,   Method: Compositional matrix adjust.
 Identities = 82/117 (70%), Positives = 99/117 (84%)
 Frame = -1

Query: 121 LKMKGDYFRYLSEVASGENKQTTVSNSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFY 180
           LKMKGDY+RYLSEV+ GE ++  V  S +AY+EA +++K+ +  THPIRLGLALNFSVF+
Sbjct: 374 LKMKGDYYRYLSEVSQGEQRKENVGKSMEAYKEATDMAKERLSSTHPIRLGLALNFSVFH 195

Query: 181 YEILNSPEKACSLAKTAFDEAIAELDTLNEESYKDSTLIMQLLRDNLTLWTSENQGD 237
           YEI N P++AC LAK AFDEAI  LD LNEESYKDSTLIMQLLRDNLTLWTS++QG+
Sbjct: 194 YEIKNCPDEACRLAKIAFDEAIQCLDQLNEESYKDSTLIMQLLRDNLTLWTSDSQGE 24
>17028
          Length = 1078

 Score =  141 bits (356), Expect = 2e-34,   Method: Compositional matrix adjust.
 Identities = 67/102 (65%), Positives = 82/102 (80%), Gaps = 1/102 (0%)
 Frame = +1

Query: 140 KQTTVSNSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYEILNSPEKACSLAKTAFD 199
           +Q  V+ +Q+AY +A E++K+ M PTHP RLGLALN+SVFYYEILNS +KAC LAKTAFD
Sbjct: 25  EQEAVTKAQEAYNKAMEVAKQSMAPTHPNRLGLALNYSVFYYEILNSQDKACDLAKTAFD 204

Query: 200 EAIAELDTLNE-ESYKDSTLIMQLLRDNLTLWTSENQGDEGD 240
           EAI E+D   E +  KDSTLIMQLLRDNLTLWTS++  + GD
Sbjct: 205 EAIQEMDQCGERDDCKDSTLIMQLLRDNLTLWTSDSNAENGD 330
>15092
          Length = 692

 Score =  129 bits (323), Expect = 2e-30,   Method: Compositional matrix adjust.
 Identities = 66/106 (62%), Positives = 78/106 (73%), Gaps = 8/106 (7%)
 Frame = +3

Query: 9   VQKAKLAEQAERYDDMAAAMKAVTEQGHE--------LSNEERNLLSVAYKNVVGARRSS 60
           V  AK+AEQAERYDDMA +M     +G+         L NEERNLLSVAYKNVVGARRS+
Sbjct: 243 VHAAKIAEQAERYDDMAESMHKCVVEGYSANGDKSSTLDNEERNLLSVAYKNVVGARRSA 422

Query: 61  WRVISSIEQKTERNEKKQQMGKEYREKIEAELQDICNDVLELLDKY 106
           WRVISSIEQKTE N+KK +M K+YREK+E EL++IC  VL  +  Y
Sbjct: 423 WRVISSIEQKTENNDKKLEMAKKYREKVEKELKEICTQVLVRIHHY 560
>27988
          Length = 448

 Score = 69.7 bits (169), Expect(2) = 2e-20,   Method: Compositional matrix adjust.
 Identities = 34/58 (58%), Positives = 43/58 (74%)
 Frame = +3

Query: 45  LLSVAYKNVVGARRSSWRVISSIEQKTERNEKKQQMGKEYREKIEAELQDICNDVLEL 102
           L SVAYKNVVGARRSSWRVI  IEQK E   +K++  + +R+ +E EL   CN+VL+L
Sbjct: 276 LFSVAYKNVVGARRSSWRVICMIEQKAETQPRKEK-ARAFRKDVEKELDATCNEVLKL 446

 Score = 46.2 bits (108), Expect(2) = 2e-20,   Method: Compositional matrix adjust.
 Identities = 24/37 (64%), Positives = 26/37 (70%)
 Frame = +2

Query: 7   ELVQKAKLAEQAERYDDMAAAMKAVTEQGHELSNEER 43
           +L+  AKLAEQAERYDDMA AMK VTE    L  E R
Sbjct: 161 DLISFAKLAEQAERYDDMAKAMKKVTENDKTLMQESR 271
>03892
          Length = 1043

 Score = 26.9 bits (58), Expect = 7.7,   Method: Compositional matrix adjust.
 Identities = 13/39 (33%), Positives = 24/39 (61%)
 Frame = +1

Query: 7   ELVQKAKLAEQAERYDDMAAAMKAVTEQGHELSNEERNL 45
           E +Q+++LAE+ E  DD+    K   ++G + S  +R+L
Sbjct: 604 EHLQESRLAEREEDRDDICGRQKRRRQEGPQTSRGQRSL 720
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|38079542|ref|XP_144196.2| PREDICTED: guanine
nucleotide binding protein, alpha transducing 3 [Mus musculus]
         (354 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

11965                                                                 318   1e-87
13527                                                                 195   2e-50
29196                                                                 130   8e-31
20516                                                                 112   3e-25
34094                                                                  59   2e-09
08153                                                                  43   2e-04
09827                                                                  42   3e-04
10862                                                                  40   0.001
18949                                                                  39   0.004
11378                                                                  38   0.005
18208                                                                  31   0.71 
00308                                                                  28   7.3  
01599                                                                  27   9.3  
>11965
          Length = 3256

 Score =  318 bits (816), Expect = 1e-87,   Method: Compositional matrix adjust.
 Identities = 147/222 (66%), Positives = 176/222 (79%)
 Frame = +1

Query: 133 DPGIQACFERASEYQLNDSAAYYLNDLDRLTAPGYVPNEQDVLHSRVKTTGIIETQFSFK 192
           D G+Q CF R++EYQLNDSA Y+L+DLDRL    Y+P EQD+L +RVKTTGI+E  FSFK
Sbjct: 1   DSGVQDCFSRSNEYQLNDSAKYFLDDLDRLGTKDYMPTEQDILRTRVKTTGIVEVHFSFK 180

Query: 193 DLNFRMFDVGGQRSERKKWIHCFEGVTCIIFCAALSAYDMVLVEDEEVNRMHESLHLFNS 252
           +LNF++FDVGGQRSERKKWIHCFE VT IIFC A+S YD VL EDE  NRM ESL LF+S
Sbjct: 181 NLNFKLFDVGGQRSERKKWIHCFEDVTAIIFCVAMSEYDQVLHEDETTNRMQESLKLFDS 360

Query: 253 ICNHKYFATTSIVLFLNKKDLFQEKVAKVHLSICFPEYTGPNTFEDAGNYIKNQFLDLNL 312
           ICN+K+F  TSI+LFLNKKDLF+EK+ K  L++CFPEYTG  T+E+   YI+ QF   N 
Sbjct: 361 ICNNKWFTDTSIILFLNKKDLFEEKIKKSPLTVCFPEYTGKQTYEEVAAYIQAQFEAKN- 537

Query: 313 KKEDKEIYSHMTCATDTQNVKFVFDAVTDIIIKENLKDCGLF 354
           K   KEIY H TCATDT N++FVFDAVTD+II  NL+ CGL+
Sbjct: 538 KSSQKEIYCHQTCATDTNNIQFVFDAVTDVIIANNLRGCGLY 663
>13527
          Length = 1091

 Score =  195 bits (496), Expect = 2e-50,   Method: Compositional matrix adjust.
 Identities = 90/176 (51%), Positives = 131/176 (74%), Gaps = 1/176 (0%)
 Frame = -2

Query: 23  LQEDAERDARTVKLLLLGAGESGKSTIVKQMKIIHKNGYSKQECMEFKAVIYSNTLQSIL 82
           L+ED  + A+ +KLLLLGAGESGKSTIVKQMKIIH+ G++ ++  +++ V++SNT+QS++
Sbjct: 976 LKEDGMQAAKDIKLLLLGAGESGKSTIVKQMKIIHEGGFTSEDNKQYRPVVFSNTIQSLV 797

Query: 83  AIVKAMATLGIDYVNPRSREDQEQLHSMANTLEDGD-MTPQLAEIIKRLWGDPGIQACFE 141
           AI++AM TL I + +     D + +  +   +ED +  + +L   ++RLW D G+Q CF 
Sbjct: 796 AIIRAMGTLSIPFGDNERESDAKMVLDVIARMEDTEPFSEELLAAMERLWMDSGVQDCFS 617

Query: 142 RASEYQLNDSAAYYLNDLDRLTAPGYVPNEQDVLHSRVKTTGIIETQFSFKDLNFR 197
           R++EYQLNDSA Y+L+DLDRL    Y+P EQD+L +RVKTTGI+E  FSFK+LNF+
Sbjct: 616 RSNEYQLNDSAKYFLDDLDRLGTKDYMPTEQDILRTRVKTTGIVEVHFSFKNLNFK 449
>29196
          Length = 431

 Score =  130 bits (327), Expect = 8e-31,   Method: Compositional matrix adjust.
 Identities = 72/145 (49%), Positives = 89/145 (61%), Gaps = 4/145 (2%)
 Frame = -2

Query: 127 IKRLWGDPGIQACFERASEYQ----LNDSAAYYLNDLDRLTAPGYVPNEQDVLHSRVKTT 182
           +KRLW D G+Q C   A+       LN S    +    R+T+    PN +       +  
Sbjct: 424 MKRLWLDSGVQECSRAATNTN*TIPLNISWMI*IG*ALRITSQ---PN-RTFCAPESRPP 257

Query: 183 GIIETQFSFKDLNFRMFDVGGQRSERKKWIHCFEGVTCIIFCAALSAYDMVLVEDEEVNR 242
            +       K+LNF++FDVGGQRSERKKWIHCFE VT IIFC A+S YD VL EDE  NR
Sbjct: 256 AL*RFISPLKNLNFKLFDVGGQRSERKKWIHCFEDVTAIIFCVAMSEYDQVLHEDETTNR 77

Query: 243 MHESLHLFNSICNHKYFATTSIVLF 267
           M ESL LF+SICN+K+F  TSI+LF
Sbjct: 76  MQESLKLFDSICNNKWFTDTSIILF 2
>20516
          Length = 534

 Score =  112 bits (279), Expect = 3e-25,   Method: Compositional matrix adjust.
 Identities = 63/161 (39%), Positives = 93/161 (57%), Gaps = 1/161 (0%)
 Frame = +2

Query: 190 SFKDLNFRMFDV-GGQRSERKKWIHCFEGVTCIIFCAALSAYDMVLVEDEEVNRMHESLH 248
           +F+++ F + +V GGQRS+R+KW  CF G+T I+F AA S +D VL+ED + NR+ ES  
Sbjct: 41  TFRNIFFLVGEVTGGQRSQRQKWYQCFVGITSILFLAASSEFDQVLMEDRKTNRLQESCD 220

Query: 249 LFNSICNHKYFATTSIVLFLNKKDLFQEKVAKVHLSICFPEYTGPNTFEDAGNYIKNQFL 308
           +F +I N+K F+  SI+LFLNK DL Q+K     L   F  ++G +        I    +
Sbjct: 221 IFETIINNKSFSGVSIILFLNKMDLLQDKN*ACQLRRLFSRFSG*SQGH*CSQSI*ASAV 400

Query: 309 DLNLKKEDKEIYSHMTCATDTQNVKFVFDAVTDIIIKENLK 349
                   +    H T A DT+N+K VF  V D I+ +NL+
Sbjct: 401 *FAPT*SKQTFVHHFTTAIDTENIKHVFQDVKDTILHDNLR 523
>34094
          Length = 452

 Score = 59.3 bits (142), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 22/45 (48%), Positives = 38/45 (84%)
 Frame = +1

Query: 54  KIIHKNGYSKQECMEFKAVIYSNTLQSILAIVKAMATLGIDYVNP 98
           +IIH+ GYS++EC+++K V+YSN +QS++AIV+AM  L +++ +P
Sbjct: 103 RIIHEKGYSQEECLQYKPVVYSNAIQSMIAIVRAMNLLSVEFGHP 237
>08153
          Length = 1703

 Score = 42.7 bits (99), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 25/97 (25%), Positives = 45/97 (46%)
 Frame = +1

Query: 177 SRVKTTGIIETQFSFKDLNFRMFDVGGQRSERKKWIHCFEGVTCIIFCAALSAYDMVLVE 236
           + + T G       +K+++F ++DVGGQ   R  W H F+    +IF          +V+
Sbjct: 163 TTIPTIGFNVETVEYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIF----------VVD 312

Query: 237 DEEVNRMHESLHLFNSICNHKYFATTSIVLFLNKKDL 273
             +  R++E+      + N        I++F NK+DL
Sbjct: 313 SNDRERINEAKEELARMLNEDDLRDAIILVFANKQDL 423
>09827
          Length = 1201

 Score = 42.0 bits (97), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 24/97 (24%), Positives = 44/97 (45%)
 Frame = -3

Query: 177  SRVKTTGIIETQFSFKDLNFRMFDVGGQRSERKKWIHCFEGVTCIIFCAALSAYDMVLVE 236
            + + T G       +K+++F ++DVGGQ   R  W H F+    +IF          +V+
Sbjct: 1034 TTIPTIGFNVETVEYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIF----------VVD 885

Query: 237  DEEVNRMHESLHLFNSICNHKYFATTSIVLFLNKKDL 273
              +  R+ E+      + N        +++F NK+DL
Sbjct: 884  SNDKERVQEAREELTRMLNEDELRDAVLLVFANKQDL 774
>10862
          Length = 2896

 Score = 40.0 bits (92), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 23/84 (27%), Positives = 40/84 (47%)
 Frame = -3

Query: 190  SFKDLNFRMFDVGGQRSERKKWIHCFEGVTCIIFCAALSAYDMVLVEDEEVNRMHESLHL 249
              ++  F ++DVGGQ   R  W H + G   +IF          +V+  + +R+ E+   
Sbjct: 2498 QLQECQFNVWDVGGQDKIRPLWRHYYTGTQGLIF----------VVDCADRDRIDEARQE 2349

Query: 250  FNSICNHKYFATTSIVLFLNKKDL 273
             + I N +      I++F NK+DL
Sbjct: 2348 LHRIINDREMRDAIILIFANKQDL 2277
>18949
          Length = 414

 Score = 38.5 bits (88), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 24/97 (24%), Positives = 43/97 (44%), Gaps = 1/97 (1%)
 Frame = +3

Query: 177 SRVKTTGIIETQ-FSFKDLNFRMFDVGGQRSERKKWIHCFEGVTCIIFCAALSAYDMVLV 235
           S+ + TG+  ++  S   + F  FD+GG R  R+ W   F  V  I+F          +V
Sbjct: 3   SQHRPTGLPTSEELSMGGMTFTTFDLGGHRQARRVWKDYFPAVDGIVF----------IV 152

Query: 236 EDEEVNRMHESLHLFNSICNHKYFATTSIVLFLNKKD 272
           +  +  R+ E+    +S+      A   +++  NK D
Sbjct: 153 DVHDTERITEAKAELDSLLRDDQIADIPVLVLGNKMD 263
>11378
          Length = 1688

 Score = 38.1 bits (87), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 28/102 (27%), Positives = 43/102 (42%)
 Frame = +3

Query: 171 EQDVLHSRVKTTGIIETQFSFKDLNFRMFDVGGQRSERKKWIHCFEGVTCIIFCAALSAY 230
           + D +   V T      + S   + F  FD+GG R  R+ W   F  V  I+F       
Sbjct: 384 KDDKMAQHVPTLHPTSEELSMGGMRFTTFDLGGHRQARRVWKDYFPAVDGIVF------- 542

Query: 231 DMVLVEDEEVNRMHESLHLFNSICNHKYFATTSIVLFLNKKD 272
            +V V D E  R+ E+    +S+   +  A   I++  NK D
Sbjct: 543 -LVDVHDRE--RLVEAKAELDSLMTDEQVANAPILVLGNKID 659
>18208
          Length = 458

 Score = 31.2 bits (69), Expect = 0.71,   Method: Compositional matrix adjust.
 Identities = 14/55 (25%), Positives = 24/55 (43%)
 Frame = -1

Query: 192 KDLNFRMFDVGGQRSERKKWIHCFEGVTCIIFCAALSAYDMVLVEDEEVNRMHES 246
           K     ++D+GGQR  R  W + FE    +I+           ++  +  RM E+
Sbjct: 176 KGFKLNVWDIGGQRRIRPYWKNYFENTDLLIYV----------IDSSDTKRMEET 42
>00308
          Length = 1759

 Score = 27.7 bits (60), Expect = 7.3,   Method: Compositional matrix adjust.
 Identities = 18/71 (25%), Positives = 31/71 (43%), Gaps = 2/71 (2%)
 Frame = +3

Query: 159  LDRLTAPGYVPNEQDVLHSRVKTTGIIETQFSFKDLNFR--MFDVGGQRSERKKWIHCFE 216
                +  GY  N   +LH  ++   I++  + F + N    M  V  Q    +    CF 
Sbjct: 1143 FSEFSVIGYCTNAY-ILH*AIQDV-IVQLDYYFNECNVSCYMMPVYSQLKWNE*SAACFR 1316

Query: 217  GVTCIIFCAAL 227
             VTC++ CA++
Sbjct: 1317 SVTCVLICASI 1349
>01599
          Length = 1883

 Score = 27.3 bits (59), Expect = 9.3,   Method: Compositional matrix adjust.
 Identities = 18/67 (26%), Positives = 28/67 (41%)
 Frame = +3

Query: 164 APGYVPNEQDVLHSRVKTTGIIETQFSFKDLNFRMFDVGGQRSERKKWIHCFEGVTCIIF 223
           APG+     +  H+   T    + +  F  L    FD    R ER++W H  + V  I  
Sbjct: 354 APGWSIKRDENTHTHTNTK---KNKLCFLKLTIARFDF--PRGERERWYHPCKHVLWISL 518

Query: 224 CAALSAY 230
           CA  + +
Sbjct: 519 CACGTVF 539
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6680041|ref|NP_032166.1| rod-type transducin alpha
subunit [Mus musculus]
         (350 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

11965                                                                 318   2e-87
13527                                                                 203   6e-53
29196                                                                 120   9e-28
20516                                                                 107   8e-24
34094                                                                  59   3e-09
08153                                                                  45   6e-05
09827                                                                  42   3e-04
10862                                                                  41   9e-04
18949                                                                  39   0.004
11378                                                                  37   0.010
18208                                                                  32   0.52 
08487                                                                  28   7.2  
31464                                                                  27   8.4  
>11965
          Length = 3256

 Score =  318 bits (814), Expect = 2e-87,   Method: Compositional matrix adjust.
 Identities = 146/222 (65%), Positives = 178/222 (80%)
 Frame = +1

Query: 129 DSGIQACFDRASEYQLNDSAGYYLSDLERLVTPGYVPTEQDVLRSRVKTTGIIETQFSFK 188
           DSG+Q CF R++EYQLNDSA Y+L DL+RL T  Y+PTEQD+LR+RVKTTGI+E  FSFK
Sbjct: 1   DSGVQDCFSRSNEYQLNDSAKYFLDDLDRLGTKDYMPTEQDILRTRVKTTGIVEVHFSFK 180

Query: 189 DLNFRMFDVGGQRSERKKWIHCFEGVTCIIFIAALSAYDMVLVEDDEVNRMHESLHLFNS 248
           +LNF++FDVGGQRSERKKWIHCFE VT IIF  A+S YD VL ED+  NRM ESL LF+S
Sbjct: 181 NLNFKLFDVGGQRSERKKWIHCFEDVTAIIFCVAMSEYDQVLHEDETTNRMQESLKLFDS 360

Query: 249 ICNHRYFATTSIVLFLNKKDVFSEKIKKAHLSICFPDYDGPNTYEDAGNYIKVQFLELNM 308
           ICN+++F  TSI+LFLNKKD+F EKIKK+ L++CFP+Y G  TYE+   YI+ QF E   
Sbjct: 361 ICNNKWFTDTSIILFLNKKDLFEEKIKKSPLTVCFPEYTGKQTYEEVAAYIQAQF-EAKN 537

Query: 309 RRDVKEIYSHMTCATDTQNVKFVFDAVTDIIIKENLKDCGLF 350
           +   KEIY H TCATDT N++FVFDAVTD+II  NL+ CGL+
Sbjct: 538 KSSQKEIYCHQTCATDTNNIQFVFDAVTDVIIANNLRGCGLY 663
>13527
          Length = 1091

 Score =  203 bits (517), Expect = 6e-53,   Method: Compositional matrix adjust.
 Identities = 101/199 (50%), Positives = 143/199 (71%), Gaps = 6/199 (3%)
 Frame = -2

Query: 1    MGAGASAEEK----HSRXXXXXXXXXXXXXXRTVKLLLLGAGESGKSTIVKQMKIIHQDG 56
            MG   SAEE+     S+              + +KLLLLGAGESGKSTIVKQMKIIH+ G
Sbjct: 1042 MGCTLSAEERAAMERSKAIEKNLKEDGMQAAKDIKLLLLGAGESGKSTIVKQMKIIHEGG 863

Query: 57   YSLEECLEFIAIIYGNTLQSILAIVRAMTTLNIQYGDSARQDDARKLMHMADTIEEGTMP 116
            ++ E+  ++  +++ NT+QS++AI+RAM TL+I +GD+ R+ DA+ ++ +   +E+ T P
Sbjct: 862  FTSEDNKQYRPVVFSNTIQSLVAIIRAMGTLSIPFGDNERESDAKMVLDVIARMED-TEP 686

Query: 117  --KEMSDIIQRLWKDSGIQACFDRASEYQLNDSAGYYLSDLERLVTPGYVPTEQDVLRSR 174
              +E+   ++RLW DSG+Q CF R++EYQLNDSA Y+L DL+RL T  Y+PTEQD+LR+R
Sbjct: 685  FSEELLAAMERLWMDSGVQDCFSRSNEYQLNDSAKYFLDDLDRLGTKDYMPTEQDILRTR 506

Query: 175  VKTTGIIETQFSFKDLNFR 193
            VKTTGI+E  FSFK+LNF+
Sbjct: 505  VKTTGIVEVHFSFKNLNFK 449
>29196
          Length = 431

 Score =  120 bits (301), Expect = 9e-28,   Method: Compositional matrix adjust.
 Identities = 67/145 (46%), Positives = 87/145 (60%), Gaps = 4/145 (2%)
 Frame = -2

Query: 123 IQRLWKDSGIQACFDRASEYQ----LNDSAGYYLSDLERLVTPGYVPTEQDVLRSRVKTT 178
           ++RLW DSG+Q C   A+       LN S    +    R+ +    P  +       +  
Sbjct: 424 MKRLWLDSGVQECSRAATNTN*TIPLNISWMI*IG*ALRITSQ---PN-RTFCAPESRPP 257

Query: 179 GIIETQFSFKDLNFRMFDVGGQRSERKKWIHCFEGVTCIIFIAALSAYDMVLVEDDEVNR 238
            +       K+LNF++FDVGGQRSERKKWIHCFE VT IIF  A+S YD VL ED+  NR
Sbjct: 256 AL*RFISPLKNLNFKLFDVGGQRSERKKWIHCFEDVTAIIFCVAMSEYDQVLHEDETTNR 77

Query: 239 MHESLHLFNSICNHRYFATTSIVLF 263
           M ESL LF+SICN+++F  TSI+LF
Sbjct: 76  MQESLKLFDSICNNKWFTDTSIILF 2
>20516
          Length = 534

 Score =  107 bits (266), Expect = 8e-24,   Method: Compositional matrix adjust.
 Identities = 60/161 (37%), Positives = 92/161 (57%), Gaps = 1/161 (0%)
 Frame = +2

Query: 186 SFKDLNFRMFDV-GGQRSERKKWIHCFEGVTCIIFIAALSAYDMVLVEDDEVNRMHESLH 244
           +F+++ F + +V GGQRS+R+KW  CF G+T I+F+AA S +D VL+ED + NR+ ES  
Sbjct: 41  TFRNIFFLVGEVTGGQRSQRQKWYQCFVGITSILFLAASSEFDQVLMEDRKTNRLQESCD 220

Query: 245 LFNSICNHRYFATTSIVLFLNKKDVFSEKIKKAHLSICFPDYDGPNTYEDAGNYIKVQFL 304
           +F +I N++ F+  SI+LFLNK D+  +K     L   F  + G +        I    +
Sbjct: 221 IFETIINNKSFSGVSIILFLNKMDLLQDKN*ACQLRRLFSRFSG*SQGH*CSQSI*ASAV 400

Query: 305 ELNMRRDVKEIYSHMTCATDTQNVKFVFDAVTDIIIKENLK 345
                   +    H T A DT+N+K VF  V D I+ +NL+
Sbjct: 401 *FAPT*SKQTFVHHFTTAIDTENIKHVFQDVKDTILHDNLR 523
>34094
          Length = 452

 Score = 59.3 bits (142), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 23/47 (48%), Positives = 36/47 (76%)
 Frame = +1

Query: 50  KIIHQDGYSLEECLEFIAIIYGNTLQSILAIVRAMTTLNIQYGDSAR 96
           +IIH+ GYS EECL++  ++Y N +QS++AIVRAM  L++++G   R
Sbjct: 103 RIIHEKGYSQEECLQYKPVVYSNAIQSMIAIVRAMNLLSVEFGHPDR 243
>08153
          Length = 1703

 Score = 44.7 bits (104), Expect = 6e-05,   Method: Compositional matrix adjust.
 Identities = 28/113 (24%), Positives = 52/113 (46%), Gaps = 3/113 (2%)
 Frame = +1

Query: 173 SRVKTTGIIETQFSFKDLNFRMFDVGGQRSERKKWIHCFEGVTCIIFIAALSAYDMVLVE 232
           + + T G       +K+++F ++DVGGQ   R  W H F+    +IF+          V+
Sbjct: 163 TTIPTIGFNVETVEYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFV----------VD 312

Query: 233 DDEVNRMHESLHLFNSICNHRYFATTSIVLFLNKKDV---FSEKIKKAHLSIC 282
            ++  R++E+      + N        I++F NK+D+   +S     AHL + 
Sbjct: 313 SNDRERINEAKEELARMLNEDDLRDAIILVFANKQDLPNAYSASEVTAHLGLA 471
>09827
          Length = 1201

 Score = 42.4 bits (98), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 23/97 (23%), Positives = 45/97 (46%)
 Frame = -3

Query: 173  SRVKTTGIIETQFSFKDLNFRMFDVGGQRSERKKWIHCFEGVTCIIFIAALSAYDMVLVE 232
            + + T G       +K+++F ++DVGGQ   R  W H F+    +IF+          V+
Sbjct: 1034 TTIPTIGFNVETVEYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFV----------VD 885

Query: 233  DDEVNRMHESLHLFNSICNHRYFATTSIVLFLNKKDV 269
             ++  R+ E+      + N        +++F NK+D+
Sbjct: 884  SNDKERVQEAREELTRMLNEDELRDAVLLVFANKQDL 774
>10862
          Length = 2896

 Score = 40.8 bits (94), Expect = 9e-04,   Method: Compositional matrix adjust.
 Identities = 23/84 (27%), Positives = 38/84 (45%)
 Frame = -3

Query: 186  SFKDLNFRMFDVGGQRSERKKWIHCFEGVTCIIFIAALSAYDMVLVEDDEVNRMHESLHL 245
              ++  F ++DVGGQ   R  W H + G   +IF+   +  D          R+ E+   
Sbjct: 2498 QLQECQFNVWDVGGQDKIRPLWRHYYTGTQGLIFVVDCADRD----------RIDEARQE 2349

Query: 246  FNSICNHRYFATTSIVLFLNKKDV 269
             + I N R      I++F NK+D+
Sbjct: 2348 LHRIINDREMRDAIILIFANKQDL 2277
>18949
          Length = 414

 Score = 38.5 bits (88), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 28/97 (28%), Positives = 44/97 (45%), Gaps = 1/97 (1%)
 Frame = +3

Query: 173 SRVKTTGIIETQ-FSFKDLNFRMFDVGGQRSERKKWIHCFEGVTCIIFIAALSAYDMVLV 231
           S+ + TG+  ++  S   + F  FD+GG R  R+ W   F  V  I+FI        V V
Sbjct: 3   SQHRPTGLPTSEELSMGGMTFTTFDLGGHRQARRVWKDYFPAVDGIVFI--------VDV 158

Query: 232 EDDEVNRMHESLHLFNSICNHRYFATTSIVLFLNKKD 268
            D E  R+ E+    +S+      A   +++  NK D
Sbjct: 159 HDTE--RITEAKAELDSLLRDDQIADIPVLVLGNKMD 263
>11378
          Length = 1688

 Score = 37.4 bits (85), Expect = 0.010,   Method: Compositional matrix adjust.
 Identities = 28/102 (27%), Positives = 42/102 (41%)
 Frame = +3

Query: 167 EQDVLRSRVKTTGIIETQFSFKDLNFRMFDVGGQRSERKKWIHCFEGVTCIIFIAALSAY 226
           + D +   V T      + S   + F  FD+GG R  R+ W   F  V  I+F+      
Sbjct: 384 KDDKMAQHVPTLHPTSEELSMGGMRFTTFDLGGHRQARRVWKDYFPAVDGIVFL------ 545

Query: 227 DMVLVEDDEVNRMHESLHLFNSICNHRYFATTSIVLFLNKKD 268
             V V D E  R+ E+    +S+      A   I++  NK D
Sbjct: 546 --VDVHDRE--RLVEAKAELDSLMTDEQVANAPILVLGNKID 659
>18208
          Length = 458

 Score = 31.6 bits (70), Expect = 0.52,   Method: Compositional matrix adjust.
 Identities = 14/55 (25%), Positives = 25/55 (45%)
 Frame = -1

Query: 188 KDLNFRMFDVGGQRSERKKWIHCFEGVTCIIFIAALSAYDMVLVEDDEVNRMHES 242
           K     ++D+GGQR  R  W + FE    +I++          ++  +  RM E+
Sbjct: 176 KGFKLNVWDIGGQRRIRPYWKNYFENTDLLIYV----------IDSSDTKRMEET 42
>08487
          Length = 1198

 Score = 27.7 bits (60), Expect = 7.2,   Method: Compositional matrix adjust.
 Identities = 13/34 (38%), Positives = 22/34 (64%), Gaps = 2/34 (5%)
 Frame = -3

Query: 292 YEDAGNYIKVQFLELNMR--RDVKEIYSHMTCAT 323
           Y +  NYIK + LEL ++  +D++ I+   TC+T
Sbjct: 185 YVNCKNYIKTEHLELTIKVVKDIEIIFLICTCST 84
>31464
          Length = 946

 Score = 27.3 bits (59), Expect = 8.4,   Method: Compositional matrix adjust.
 Identities = 10/18 (55%), Positives = 12/18 (66%)
 Frame = +1

Query: 124 QRLWKDSGIQACFDRASE 141
           +R W D+G   CFDRA E
Sbjct: 841 ERAWHDAGEAVCFDRAGE 894
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6756041|ref|NP_035870.1| tyrosine
3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
polypeptide [Mus musculus]
         (245 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

12344                                                                 318   2e-87
13465                                                                 178   2e-45
33715                                                                 171   3e-43
17028                                                                 136   9e-33
15092                                                                 124   4e-29
27988                                                                  70   5e-20
03892                                                                  27   9.1  
>12344
          Length = 1658

 Score =  318 bits (814), Expect = 2e-87,   Method: Compositional matrix adjust.
 Identities = 157/232 (67%), Positives = 185/232 (79%)
 Frame = +2

Query: 2   DKNELVQKAKLAEQAERYDDMAACMKSVTEQGAELSNEERNLLSVAYKNVVGARRSSWRV 61
           D+ + V +AK   +AERYD+M   MK V     EL+ EERNLLSVAYKNV+GARR+SWR+
Sbjct: 62  DREDQVYQAKQLNRAERYDEMVKFMKIVACMDVELTVEERNLLSVAYKNVIGARRASWRI 241

Query: 62  VSSIEQKTEGAEKKQQMAREYREKIETELRDICNDVLSLLEKFLIPNASQPESKVFYLKM 121
           VSS+EQK +  E K+ + +EYR KIE EL+DIC DVL +LEK LI NA+  ESKVFY KM
Sbjct: 242 VSSLEQKEDKCEDKKAINKEYRMKIEKELKDICEDVLDILEKHLIVNANTGESKVFYYKM 421

Query: 122 KGDYYRYLAEVAAGDDKKGIVDQSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYEI 181
           KGDY+RYLAE A G+D+K   + S  AY+ A +I+  E+ PTHPIRLGLALNFSVFYYEI
Sbjct: 422 KGDYHRYLAEFAVGNDRKEAAENSLVAYKAASDIAMIELAPTHPIRLGLALNFSVFYYEI 601

Query: 182 LNSPEKACSLAKTAFDEAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSDTQ 233
           LNSP++AC LAK AFD+AIAELDTLSEESYKDSTLIMQLLRDNLTLWTSD Q
Sbjct: 602 LNSPDRACRLAKAAFDDAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSDMQ 757
>13465
          Length = 596

 Score =  178 bits (451), Expect = 2e-45,   Method: Compositional matrix adjust.
 Identities = 88/151 (58%), Positives = 113/151 (74%), Gaps = 2/151 (1%)
 Frame = +2

Query: 2   DKNELVQKAKLAEQAERYDDMAACMKSVTEQGAELSNEERNLLSVAYKNVVGARRSSWRV 61
           D+++ V +AKLAEQAERYD+M   MK V   G +L+ EERNLLSVAYKNV+GARR+SWR+
Sbjct: 116 DRDDFVYQAKLAEQAERYDEMVEAMKKVASMGNDLTVEERNLLSVAYKNVIGARRASWRI 295

Query: 62  VSSIEQK--TEGAEKKQQMAREYREKIETELRDICNDVLSLLEKFLIPNASQPESKVFYL 119
           VSS+EQK   +    K +M + YR++IETEL+ IC DVL +++  LIP+ +Q ESKVFY 
Sbjct: 296 VSSVEQKDLDKPDPDKGKMTKGYRQQIETELKQICEDVLKIIDDHLIPSTTQGESKVFYY 475

Query: 120 KMKGDYYRYLAEVAAGDDKKGIVDQSQQAYQ 150
           KMKGDYYRYLAE A GD +K   + S  AY+
Sbjct: 476 KMKGDYYRYLAEFATGDPRKEAAESSLVAYK 568
>33715
          Length = 434

 Score =  171 bits (432), Expect = 3e-43,   Method: Compositional matrix adjust.
 Identities = 81/115 (70%), Positives = 98/115 (85%)
 Frame = -1

Query: 119 LKMKGDYYRYLAEVAAGDDKKGIVDQSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFY 178
           LKMKGDYYRYL+EV+ G+ +K  V +S +AY+EA +++K+ +  THPIRLGLALNFSVF+
Sbjct: 374 LKMKGDYYRYLSEVSQGEQRKENVGKSMEAYKEATDMAKERLSSTHPIRLGLALNFSVFH 195

Query: 179 YEILNSPEKACSLAKTAFDEAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSDTQ 233
           YEI N P++AC LAK AFDEAI  LD L+EESYKDSTLIMQLLRDNLTLWTSD+Q
Sbjct: 194 YEIKNCPDEACRLAKIAFDEAIQCLDQLNEESYKDSTLIMQLLRDNLTLWTSDSQ 30
>17028
          Length = 1078

 Score =  136 bits (342), Expect = 9e-33,   Method: Compositional matrix adjust.
 Identities = 65/92 (70%), Positives = 77/92 (83%), Gaps = 1/92 (1%)
 Frame = +1

Query: 142 VDQSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYEILNSPEKACSLAKTAFDEAIA 201
           V ++Q+AY +A E++K+ M PTHP RLGLALN+SVFYYEILNS +KAC LAKTAFDEAI 
Sbjct: 37  VTKAQEAYNKAMEVAKQSMAPTHPNRLGLALNYSVFYYEILNSQDKACDLAKTAFDEAIQ 216

Query: 202 ELDTLSE-ESYKDSTLIMQLLRDNLTLWTSDT 232
           E+D   E +  KDSTLIMQLLRDNLTLWTSD+
Sbjct: 217 EMDQCGERDDCKDSTLIMQLLRDNLTLWTSDS 312
>15092
          Length = 692

 Score =  124 bits (311), Expect = 4e-29,   Method: Compositional matrix adjust.
 Identities = 63/106 (59%), Positives = 77/106 (72%), Gaps = 8/106 (7%)
 Frame = +3

Query: 7   VQKAKLAEQAERYDDMAACMKSVTEQG--------AELSNEERNLLSVAYKNVVGARRSS 58
           V  AK+AEQAERYDDMA  M     +G        + L NEERNLLSVAYKNVVGARRS+
Sbjct: 243 VHAAKIAEQAERYDDMAESMHKCVVEGYSANGDKSSTLDNEERNLLSVAYKNVVGARRSA 422

Query: 59  WRVVSSIEQKTEGAEKKQQMAREYREKIETELRDICNDVLSLLEKF 104
           WRV+SSIEQKTE  +KK +MA++YREK+E EL++IC  VL  +  +
Sbjct: 423 WRVISSIEQKTENNDKKLEMAKKYREKVEKELKEICTQVLVRIHHY 560
>27988
          Length = 448

 Score = 69.7 bits (169), Expect(2) = 5e-20,   Method: Compositional matrix adjust.
 Identities = 35/58 (60%), Positives = 43/58 (74%)
 Frame = +3

Query: 43  LLSVAYKNVVGARRSSWRVVSSIEQKTEGAEKKQQMAREYREKIETELRDICNDVLSL 100
           L SVAYKNVVGARRSSWRV+  IEQK E   +K++ AR +R+ +E EL   CN+VL L
Sbjct: 276 LFSVAYKNVVGARRSSWRVICMIEQKAETQPRKEK-ARAFRKDVEKELDATCNEVLKL 446

 Score = 44.7 bits (104), Expect(2) = 5e-20,   Method: Compositional matrix adjust.
 Identities = 23/37 (62%), Positives = 25/37 (67%)
 Frame = +2

Query: 5   ELVQKAKLAEQAERYDDMAACMKSVTEQGAELSNEER 41
           +L+  AKLAEQAERYDDMA  MK VTE    L  E R
Sbjct: 161 DLISFAKLAEQAERYDDMAKAMKKVTENDKTLMQESR 271
>03892
          Length = 1043

 Score = 26.6 bits (57), Expect = 9.1,   Method: Compositional matrix adjust.
 Identities = 13/39 (33%), Positives = 24/39 (61%)
 Frame = +1

Query: 5   ELVQKAKLAEQAERYDDMAACMKSVTEQGAELSNEERNL 43
           E +Q+++LAE+ E  DD+    K   ++G + S  +R+L
Sbjct: 604 EHLQESRLAEREEDRDDICGRQKRRRQEGPQTSRGQRSL 720
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|12963737|ref|NP_076054.1| chromosome segregation
1-like [Mus musculus]
         (971 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

11161                                                                 319   4e-87
13992                                                                 176   5e-44
20038                                                                  59   9e-09
06312                                                                  29   7.2  
>11161
          Length = 882

 Score =  319 bits (817), Expect = 4e-87,   Method: Compositional matrix adjust.
 Identities = 151/237 (63%), Positives = 189/237 (79%)
 Frame = +1

Query: 545 EIAPFVEILLTNLFKALTLPGSSENEYIMKAIMRSFSLLQEAIIPYIPTLITQLTQKLLA 604
           ++ PF   L+ NLF A+    S+ENEYIMKA+MR+ SLLQ+ I+P +P L+  LTQKL+ 
Sbjct: 1   DVKPFATELMVNLFGAMNKENSAENEYIMKAVMRTMSLLQDNILPMVPQLLQGLTQKLIL 180

Query: 605 VSKNPSKPHFNHYMFEAICLSIRITCKANPAAVVNFEEALFLVFTEILQNDVQEFIPYVF 664
           VSKNPSKPHFNHY+FE++C++IR  CK +  AV  FEEALF  FT+ILQ DVQEFIPYVF
Sbjct: 181 VSKNPSKPHFNHYLFESLCVAIRSACKHSAEAVTTFEEALFTPFTDILQQDVQEFIPYVF 360

Query: 665 QVMSLLLETHKNDIPSSYMALFPHLLQPVLWERTGNIPALVRLLQAFLERGSSTIATAAA 724
           Q++SLL+E H + +P +YMALFPHLL PVLWER GNIP LVRL+QAF+ +G++ I     
Sbjct: 361 QILSLLMELHTSTVPETYMALFPHLLAPVLWERPGNIPPLVRLIQAFITQGAAQI---EG 531

Query: 725 DKIPGLLGVFQKLIASKANDHQGFYLLNSIIEHMPPESVDQYRKQIFILLFQRLQNS 781
           DK+ GLLGVFQKL+ASK +DH+GFY+LNSIIE MP + V QY +QIFILLFQRLQ+S
Sbjct: 532 DKLNGLLGVFQKLLASKTHDHEGFYILNSIIEFMPQQLVSQYTRQIFILLFQRLQSS 702

 Score = 68.6 bits (166), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 32/55 (58%), Positives = 38/55 (69%)
 Frame = -2

Query: 223 NFQDLPEFFEDNMETWMNNFHTLLTLDNKLLQTDDXXXXXXXXXXKSQICDNAAL 277
           NFQDLPE FEDN++TWM+NF  LL  DNKLL+T+D          KSQ+CDN  L
Sbjct: 860 NFQDLPEHFEDNIKTWMDNFLQLLAADNKLLKTEDEEEAGLLEQVKSQVCDNVEL 696
>13992
          Length = 468

 Score =  176 bits (445), Expect = 5e-44,   Method: Compositional matrix adjust.
 Identities = 88/149 (59%), Positives = 99/149 (66%)
 Frame = +1

Query: 149 VLRTAHSLFKRYRHEFKSNELWTEIKLVLDAFALPLTNLFKATIELCSTHANDAXXXXXX 208
           +LRTAHS+FKRYRHEFKS ELW EIK VLD FA   T LFKAT+ L +THA+D       
Sbjct: 1   ILRTAHSIFKRYRHEFKSQELWEEIKFVLDNFASHFTELFKATMGLATTHASDPAALRVI 180

Query: 209 XXXXXXXXXXXXXXNFQDLPEFFEDNMETWMNNFHTLLTLDNKLLQTDDXXXXXXXXXXK 268
                         NFQDLPE FEDN++TWM+NF  LL  DNKLL+T+D          K
Sbjct: 181 FSSILLICKIFYSLNFQDLPEHFEDNIKTWMDNFLQLLAADNKLLKTEDEEEAGLLEQVK 360

Query: 269 SQICDNAALYAQKYDEEFQRYLPRFVTAI 297
           SQ+CDN ALYAQKYDEEF  YLP FVTAI
Sbjct: 361 SQVCDNVALYAQKYDEEFSPYLPGFVTAI 447
>20038
          Length = 986

 Score = 58.9 bits (141), Expect = 9e-09,   Method: Compositional matrix adjust.
 Identities = 52/195 (26%), Positives = 89/195 (45%), Gaps = 7/195 (3%)
 Frame = +3

Query: 7   NLQTLTEYLKKTLDPDPAIRRPAEKFLESVEGNQNY-PXXXXXXXEKSQDNVIKVCASVT 65
           ++  L E L+ TLDP+   R  AEK L  +     + P           D  ++    + 
Sbjct: 186 DVAKLVEILRATLDPNH--REEAEKQLTEIHKIIGFGPVLLQVVMADPIDMPVRQAGVIY 359

Query: 66  FKNYIKRNWRIVEDE------PNKICEADRVAIKANIVHLMLSSPEQIQKQLSDAISIIG 119
            KN + + W   E E      P  I E DR  I+ + +  ++ +P+ ++ QL   IS I 
Sbjct: 360 LKNMVTQFWSEKEVENPADPVPFSIHEQDRKHIRDHSIEAIIHAPDPVRVQLCVCISHII 539

Query: 120 REDFPQKWPDLLTEMVNRFQSGDFHVINGVLRTAHSLFKRYRHEFKSNELWTEIKLVLDA 179
           + D+P +WPD   +M    QS +     G L + + L K Y  E+K +E    + + + A
Sbjct: 540 KCDYPGRWPDAPEKMALYIQSDNHATWMGALLSIYQLVKVY--EYKRSEERNVMDMAMKA 713

Query: 180 FALPLTNLFKATIEL 194
             LP+  L++  I++
Sbjct: 714 M-LPM--LYQRIIQM 749
>06312
          Length = 822

 Score = 29.3 bits (64), Expect = 7.2,   Method: Composition-based stats.
 Identities = 16/52 (30%), Positives = 26/52 (50%)
 Frame = -3

Query: 892 DIEDTPGYQTAFSQLAFAGKKEHDPVGQMVNNPKIHLAQSLHKLSTACPGRV 943
           D+E  P    +   LA      H   GQ ++N  + LA++LH ++T   G+V
Sbjct: 394 DVEGVPDDAHSQQLLAVVAAVHHQAAGQTLHNGALGLAETLHLVTT*RVGQV 239
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6754474|ref|NP_034785.1| karyopherin (importin) alpha
2 [Mus musculus]
         (529 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

06072                                                                 219   5e-87
29389                                                                 220   9e-58
03757                                                                 136   1e-53
05915                                                                 169   3e-42
17435                                                                 152   3e-37
19838                                                                 124   2e-32
06510                                                                 122   5e-28
15699                                                                  99   6e-21
22653                                                                  42   8e-04
09672                                                                  40   0.002
05045                                                                  31   1.3  
>06072
          Length = 1397

 Score =  219 bits (558), Expect(2) = 5e-87,   Method: Compositional matrix adjust.
 Identities = 109/234 (46%), Positives = 145/234 (61%)
 Frame = +1

Query: 165 PAFISLLASPHAHISEQAVWALGNIAGDGSAFRDLVIKHGAIXXXXXXXXXXXXSTLACG 224
           P F+ LL+S    + EQAVWALGNIAGD    R+ V+    +             +++  
Sbjct: 421 PIFVRLLSSEVEDVQEQAVWALGNIAGDSPECREYVLNENILVPLLQLLSKTTSLSMS-- 594

Query: 225 YLRNLTWTLSNLCRNKNPAPPLDAVEQILPTLVRLLHHNDPEVLADSCWAISYLTDGPNE 284
             RN  W LSNLCR KNP P    V   LP L RLL H D +VLAD+CWA+SYL+DGPNE
Sbjct: 595 --RNAVWCLSNLCRGKNPPPDFTKVSPALPVLARLLFHTDKDVLADACWALSYLSDGPNE 768

Query: 285 RIEMVVKKGVVPQLVKLLGATELPIVTPALRAIGNIVTGTDEQTQKVIDAGALAVFPSLL 344
           +I+ V+  GV  +LV+LL      +V  ALR +GNIVTG D QTQ ++   AL     LL
Sbjct: 769 KIQTVIDSGVCRRLVELLMHNHQSVVAAALRVVGNIVTGDDSQTQVILSCSALPCLLHLL 948

Query: 345 TNPKTNIQKEATWTMSNITAGRQDQIQQVVNHGLVPFLVGVLSKADFKTQKEAA 398
           ++ K  I+KEA WT+SNITAG ++QIQ V++  + P L+ +L KA+FKT+K  +
Sbjct: 949 SSNKETIRKEACWTISNITAGNRNQIQDVIDTNIFPVLIEILGKAEFKTEKRGS 1110

 Score =  120 bits (301), Expect(2) = 5e-87,   Method: Compositional matrix adjust.
 Identities = 68/133 (51%), Positives = 91/133 (68%), Gaps = 3/133 (2%)
 Frame = +3

Query: 36  VELRKAKKDEQMLKRRNVS-SFPDDAT-SPLQE-NRNNQGTVNWSVEDIVKGINSNNLES 92
           ++LRK K+DE + KRRNVS S  DD T   +QE   ++ G ++    D+++ + S+ LE 
Sbjct: 33  IQLRKQKRDEHLNKRRNVSVSEVDDMTMGDIQEPTVSSTGGIS---ADMIQALYSDVLED 203

Query: 93  QLQATQAARKLLSREKQPPIDNIIRAGLIPKFVSFLGKTDCSPIQFESAWALTNIASGTS 152
           Q  ATQ  RKLLSRE  PPID +I+ G+IP+FV FL K     +QFE+AWALTNIASGTS
Sbjct: 204 QEAATQKFRKLLSREPNPPIDEVIQTGIIPRFVEFLQKETSWTLQFEAAWALTNIASGTS 383

Query: 153 EQTKAVVDGGAIP 165
            QT+ V+  GA+P
Sbjct: 384 IQTRMVIHAGAVP 422

 Score = 72.0 bits (175), Expect = 5e-13,   Method: Compositional matrix adjust.
 Identities = 37/84 (44%), Positives = 53/84 (63%), Gaps = 4/84 (4%)
 Frame = +2

Query: 388  KADFKTQKEAAWAITNYTSGGTVEQIVYLVHCGIIEPLMNLLSAKDTKIIQVILDAISNI 447
            + + + +KEAAWAITN TSGG+ EQI +LV  G I PL +LL+  D+KI+ V L  + NI
Sbjct: 1079 RQNSRRRKEAAWAITNATSGGSPEQIRFLVEQGCISPLCDLLTVMDSKIVMVALSGLENI 1258

Query: 448  FQAAEKLGE----TEKLSIMIEEC 467
             +  E+  +        ++MIEEC
Sbjct: 1259 LRLGEQDSKFNNAVNPYAVMIEEC 1330

 Score = 61.2 bits (147), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 49/205 (23%), Positives = 80/205 (39%), Gaps = 1/205 (0%)
 Frame = +1

Query: 104 LSREKQPPIDNIIRAGLIPKFVSFLGKTDCSPIQFESAWALTNIASGTSEQTKAVVDGGA 163
           L R K PP D    +  +P     L  TD   +  ++ WAL+ ++ G +E+ + V+D G 
Sbjct: 622 LCRGKNPPPDFTKVSPALPVLARLLFHTD-KDVLADACWALSYLSDGPNEKIQTVIDSGV 798

Query: 164 IPAFISLLASPHAHISEQAVWALGNIA-GDGSAFRDLVIKHGAIXXXXXXXXXXXXSTLA 222
               + LL   H  +   A+  +GNI  GD S  + +                     L+
Sbjct: 799 CRRLVELLMHNHQSVVAAALRVVGNIVTGDDSQTQVI---------------------LS 915

Query: 223 CGYLRNLTWTLSNLCRNKNPAPPLDAVEQILPTLVRLLHHNDPEVLADSCWAISYLTDGP 282
           C                             LP L+ LL  N   +  ++CW IS +T G 
Sbjct: 916 CSA---------------------------LPCLLHLLSSNKETIRKEACWTISNITAGN 1014

Query: 283 NERIEMVVKKGVVPQLVKLLGATEL 307
             +I+ V+   + P L+++LG  E 
Sbjct: 1015RNQIQDVIDTNIFPVLIEILGKAEF 1089

 Score = 38.9 bits (89), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 20/54 (37%), Positives = 31/54 (57%), Gaps = 1/54 (1%)
 Frame = +3

Query: 370 IQQVVNHGLVPFLVGVLSK-ADFKTQKEAAWAITNYTSGGTVEQIVYLVHCGII 422
           I +V+  G++P  V  L K   +  Q EAAWA+TN  SG ++ Q   ++H G +
Sbjct: 261 IDEVIQTGIIPRFVEFLQKETSWTLQFEAAWALTNIASGTSI-QTRMVIHAGAV 419

 Score = 33.9 bits (76), Expect = 0.15,   Method: Compositional matrix adjust.
 Identities = 21/52 (40%), Positives = 28/52 (53%), Gaps = 1/52 (1%)
 Frame = +2

Query: 139  ESAWALTNIASGTS-EQTKAVVDGGAIPAFISLLASPHAHISEQAVWALGNI 189
            E+AWA+TN  SG S EQ + +V+ G I     LL    + I   A+  L NI
Sbjct: 1103 EAAWAITNATSGGSPEQIRFLVEQGCISPLCDLLTVMDSKIVMVALSGLENI 1258
>29389
          Length = 1070

 Score =  220 bits (561), Expect = 9e-58,   Method: Compositional matrix adjust.
 Identities = 110/212 (51%), Positives = 145/212 (68%), Gaps = 1/212 (0%)
 Frame = +2

Query: 319 NIVTGTDEQTQKVIDAGALAVFPSLLTNPKTNIQKEATWTMSNITAGRQDQIQQVVNHGL 378
           NIVTG D QTQ V+D+GAL VF  LL +PK ++QKEA WT+SNITAG +DQIQ V++ GL
Sbjct: 2   NIVTGNDTQTQVVLDSGALQVFSYLLRHPKASLQKEAAWTLSNITAGNRDQIQAVIDAGL 181

Query: 379 VPFLVGVLSKADFKTQKEAAWAITNYTSGGTVEQIVYLVHCGIIEPLMNLLSAKDTKIIQ 438
           VP L+ ++ + DFK+QKEA WAITN TSGG++ Q+ + +    + PL +LL AKDTKII 
Sbjct: 182 VPLLIELMHRGDFKSQKEAVWAITNLTSGGSIPQVGHCMEHNCLPPLCSLLGAKDTKIIL 361

Query: 439 VILDAISNIFQAAEKLGETEKLSIMIEECGGLDKIEALQRHENESVYKASLNLIEKYFSV 498
           VILDAISN+   A+ +G+ + L   +EE GGLD+IE LQ HEN+ VYK + +LI++YF V
Sbjct: 362 VILDAISNVCSMAKTMGQLDSLCQHLEEMGGLDRIEQLQEHENQQVYKVAQSLIDQYFGV 541

Query: 499 EEEEDQNVVPETTSEGFAFQVQDGAP-GTFNF 529
           E+E      P      + F      P G F F
Sbjct: 542 EDEVGDMEAPTVEGNTYQFNEPQNVPSGGFEF 637

 Score = 55.5 bits (132), Expect = 6e-08,   Method: Compositional matrix adjust.
 Identities = 27/80 (33%), Positives = 47/80 (58%)
 Frame = +2

Query: 115 IIRAGLIPKFVSFLGKTDCSPIQFESAWALTNIASGTSEQTKAVVDGGAIPAFISLLASP 174
           ++ +G +  F S+L +   + +Q E+AW L+NI +G  +Q +AV+D G +P  I L+   
Sbjct: 38  VLDSGALQVF-SYLLRHPKASLQKEAAWTLSNITAGNRDQIQAVIDAGLVPLLIELMHRG 214

Query: 175 HAHISEQAVWALGNIAGDGS 194
                ++AVWA+ N+   GS
Sbjct: 215 DFKSQKEAVWAITNLTSGGS 274

 Score = 51.6 bits (122), Expect = 8e-07,   Method: Compositional matrix adjust.
 Identities = 42/178 (23%), Positives = 68/178 (38%), Gaps = 1/178 (0%)
 Frame = +2

Query: 146 NIASGTSEQTKAVVDGGAIPAFISLLASPHAHISEQAVWALGNIAGDGSAFRDLVIKHGA 205
           NI +G   QT+ V+D GA+  F  LL  P A + ++A                       
Sbjct: 2   NIVTGNDTQTQVVLDSGALQVFSYLLRHPKASLQKEA----------------------- 112

Query: 206 IXXXXXXXXXXXXSTLACGYLRNLTWTLSNLCRNKNPAPPLDAVEQILPTLVRLLHHNDP 265
                                    WTLSN+               ++P L+ L+H  D 
Sbjct: 113 ------------------------AWTLSNITAGNRDQIQAVIDAGLVPLLIELMHRGDF 220

Query: 266 EVLADSCWAISYLTDGPN-ERIEMVVKKGVVPQLVKLLGATELPIVTPALRAIGNIVT 322
           +   ++ WAI+ LT G +  ++   ++   +P L  LLGA +  I+   L AI N+ +
Sbjct: 221 KSQKEAVWAITNLTSGGSIPQVGHCMEHNCLPPLCSLLGAKDTKIILVILDAISNVCS 394
>03757
          Length = 2670

 Score =  136 bits (343), Expect(2) = 1e-53,   Method: Compositional matrix adjust.
 Identities = 67/139 (48%), Positives = 95/139 (68%)
 Frame = +3

Query: 386 LSKADFKTQKEAAWAITNYTSGGTVEQIVYLVHCGIIEPLMNLLSAKDTKIIQVILDAIS 445
           L+  DF+TQKEAAWAI+N T  G  +Q+ Y+V  G+I P  +LL  KDT+++ V+LD I+
Sbjct: 279 LAGGDFQTQKEAAWAISNLTISGKKDQVGYVVSQGVISPFCSLLGVKDTQVVNVVLDGIN 458

Query: 446 NIFQAAEKLGETEKLSIMIEECGGLDKIEALQRHENESVYKASLNLIEKYFSVEEEEDQN 505
           NI + A    + E L   IEECGGLDKIE+LQ HENE +YK + ++I+ YFS +E E+++
Sbjct: 459 NILKMATD--DLEPLCQAIEECGGLDKIESLQTHENEEIYKLAYDIIDHYFS-DEPEEED 629

Query: 506 VVPETTSEGFAFQVQDGAP 524
           ++P   +EGF F  Q   P
Sbjct: 630 LLPTQNTEGFQFDPQTMVP 686

 Score = 92.4 bits (228), Expect(2) = 1e-53,   Method: Compositional matrix adjust.
 Identities = 48/92 (52%), Positives = 65/92 (70%), Gaps = 4/92 (4%)
 Frame = +1

Query: 301 LLGATELPIVTPALRAIGNIVTGTDEQTQKVIDAGALAVFPSLLTNPKTNIQKEATWTMS 360
           LL   ++ + T ALRA+GNIVTGTDEQTQ V++ GAL  F +LLT+PK  I KEA   +S
Sbjct: 25  LLSHQDVKVQTAALRAVGNIVTGTDEQTQIVLNCGALTHFRALLTHPKEKINKEAVXFLS 204

Query: 361 NITAGRQDQIQQVVNHGLVPFLV----GVLSK 388
           NITAG Q Q+Q V++  L+P ++    GV+S+
Sbjct: 205 NITAGNQQQVQAVIDAELIPLIIHHLQGVISR 300

 Score = 39.7 bits (91), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 33/105 (31%), Positives = 48/105 (45%), Gaps = 10/105 (9%)
 Frame = +3

Query: 261 HH-----NDPEVLADSCWAISYLT-DGPNERIEMVVKKGVVPQLVKLLGATELPIVTPAL 314
           HH      D +   ++ WAIS LT  G  +++  VV +GV+     LLG  +  +V   L
Sbjct: 267 HHPPLAGGDFQTQKEAAWAISNLTISGKKDQVGYVVSQGVISPFCSLLGVKDTQVVNVVL 446

Query: 315 RAIGNIV-TGTDE---QTQKVIDAGALAVFPSLLTNPKTNIQKEA 355
             I NI+   TD+     Q + + G L    SL T+    I K A
Sbjct: 447 DGINNILKMATDDLEPLCQAIEECGGLDKIESLQTHENEEIYKLA 581

 Score = 31.6 bits (70), Expect = 0.87,   Method: Compositional matrix adjust.
 Identities = 25/90 (27%), Positives = 43/90 (47%), Gaps = 4/90 (4%)
 Frame = +1

Query: 385 VLSKADFKTQKEAAWAITNYTSGGTVEQIVYLVHCGIIEPLMNLLSAKDTKIIQVILDAI 444
           +LS  D K Q  A  A+ N  +G T EQ   +++CG +     LL+    KI +  +  +
Sbjct: 25  LLSHQDVKVQTAALRAVGNIVTG-TDEQTQIVLNCGALTHFRALLTHPKEKINKEAVXFL 201

Query: 445 SNIF----QAAEKLGETEKLSIMIEECGGL 470
           SNI     Q  + + + E + ++I    G+
Sbjct: 202 SNITAGNQQQVQAVIDAELIPLIIHHLQGV 291
>05915
          Length = 1020

 Score =  169 bits (427), Expect = 3e-42,   Method: Compositional matrix adjust.
 Identities = 121/319 (37%), Positives = 166/319 (52%), Gaps = 20/319 (6%)
 Frame = +1

Query: 13  RLNRFKNKGKDSTEMRRRRIEVNVELRKAKKDEQMLKRRNVSSFPDD-ATSPLQENRNNQ 71
           R+  +KNKG+D+ EMRRRR E +VELRKAKK+E +LKRRNV    DD ATSP+ +     
Sbjct: 151 RIKTYKNKGRDAEEMRRRRNETSVELRKAKKEESLLKRRNVVLSEDDLATSPVHD----- 315

Query: 72  GTVNWSVEDIVKGINSNNLESQLQATQAARKLLSREKQPPIDNIIRAGLIPKFVSFLGKT 131
            +   +++DIV GI  +++  Q +ATQA RK+LSRE+ PPI+++I++G++ + V +L K 
Sbjct: 316 ASKAPTLQDIVAGIQCSDVNKQHEATQACRKMLSRERNPPINDVIKSGVVSRLV-YLWK- 489

Query: 132 DCSPIQFESAWALTNIASGTSEQTKAVVD--GGAIPAFISLLASPHAHISEQAVWALGNI 189
            CS  +   A    ++ S          D  GG      SL  SP      + V      
Sbjct: 490 -CSKCR---AAV*GSVGSDKHSVWHQ*PDQGGGQCRRCSSLYPSPQLL---RHVCL*AGC 648

Query: 190 AGDG---------SAFRDLVIKHGAIXXXXXXXXXXXXSTLACGYLRNLTWTLSNLCR-- 238
            G G            RD     GAI               A G ++   W  +  C   
Sbjct: 649 LGPGQYCRRWAWIERLRDQQWNSGAIA--------------AVGNIQCFCWVYAQ-CDVD 783

Query: 239 ------NKNPAPPLDAVEQILPTLVRLLHHNDPEVLADSCWAISYLTDGPNERIEMVVKK 292
                  + P    D V Q LP L  LL H D EVLADSCWA+SYLTDG NE+I+ V+  
Sbjct: 784 HLQPVPQQGPPSKFDVVNQCLPALRTLLQHTDREVLADSCWALSYLTDGSNEQIQAVIDS 963

Query: 293 GVVPQLVKLLGATELPIVT 311
           GVV +LV+LLG+ E  ++T
Sbjct: 964 GVVLRLVELLGSNEPSVLT 1020

 Score = 60.5 bits (145), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 30/78 (38%), Positives = 46/78 (58%)
 Frame = +2

Query: 351 IQKEATWTMSNITAGRQDQIQQVVNHGLVPFLVGVLSKADFKTQKEAAWAITNYTSGGTV 410
           +Q EA W ++NI +G  DQ + VVN G VP  + +LS +D    ++A WA+ N    G  
Sbjct: 506 LQFEAAWALTNIASGTSDQTKVVVNAGAVPHFIRLLSSSDMSVCEQAVWALGNIAGDGPG 685

Query: 411 EQIVYLVHCGIIEPLMNL 428
            +  Y+ + GI+EPL+ L
Sbjct: 686 LRD-YVTNNGILEPLLQL 736

 Score = 48.1 bits (113), Expect = 9e-06,   Method: Compositional matrix adjust.
 Identities = 28/92 (30%), Positives = 47/92 (51%), Gaps = 1/92 (1%)
 Frame = +2

Query: 313 ALRAIGNIVTGTDEQTQKVIDAGALAVFPSLLTNPKTNIQKEATWTMSNITAGRQDQIQQ 372
           A  A+ NI +GT +QT+ V++AGA+  F  LL++   ++ ++A W + NI          
Sbjct: 518 AAWALTNIASGTSDQTKVVVNAGAVPHFIRLLSSSDMSVCEQAVWALGNIAGDGPGLRDY 697

Query: 373 VVNHGLV-PFLVGVLSKADFKTQKEAAWAITN 403
           V N+G++ P L    S       +   W I+N
Sbjct: 698 VTNNGILEPLLQLATSNVSAGFMRNVTWTISN 793

 Score = 32.3 bits (72), Expect = 0.46,   Method: Compositional matrix adjust.
 Identities = 16/51 (31%), Positives = 28/51 (54%)
 Frame = +1

Query: 336 ALAVFPSLLTNPKTNIQKEATWTMSNITAGRQDQIQQVVNHGLVPFLVGVL 386
            L    +LL +    +  ++ W +S +T G  +QIQ V++ G+V  LV +L
Sbjct: 841 CLPALRTLLQHTDREVLADSCWALSYLTDGSNEQIQAVIDSGVVLRLVELL 993
>17435
          Length = 1280

 Score =  152 bits (384), Expect = 3e-37,   Method: Compositional matrix adjust.
 Identities = 71/151 (47%), Positives = 106/151 (70%)
 Frame = +3

Query: 367 QDQIQQVVNHGLVPFLVGVLSKADFKTQKEAAWAITNYTSGGTVEQIVYLVHCGIIEPLM 426
            +Q+Q V++H L+P ++  L K DF+T+KEAAW I+N T  G  EQ+ Y++  G++ PL 
Sbjct: 3   HEQVQTVIDHELIPLVIYHLDKGDFQTKKEAAWTISNLTISGKKEQVAYVLDQGVMAPLC 182

Query: 427 NLLSAKDTKIIQVILDAISNIFQAAEKLGETEKLSIMIEECGGLDKIEALQRHENESVYK 486
           NLL  KD++++ V++DA+ NI + A    +TE +   IEECGGLD IE LQ HENE +YK
Sbjct: 183 NLLGVKDSQVLSVVMDALHNILKTA---TDTEXVCQKIEECGGLDHIENLQNHENEDIYK 353

Query: 487 ASLNLIEKYFSVEEEEDQNVVPETTSEGFAF 517
            + ++I+ YFS +E++D+ +VPE  SE FAF
Sbjct: 354 QAFDIIDNYFS-DEQQDEALVPEAGSEQFAF 443
>19838
          Length = 447

 Score =  124 bits (310), Expect(2) = 2e-32,   Method: Compositional matrix adjust.
 Identities = 64/133 (48%), Positives = 89/133 (66%)
 Frame = -2

Query: 48  LKRRNVSSFPDDATSPLQENRNNQGTVNWSVEDIVKGINSNNLESQLQATQAARKLLSRE 107
           LKRRNV +   D+T    ++ +N+   N +++ IV    S     QL A QAARKLLS +
Sbjct: 383 LKRRNVPA--QDST----DSEDNEKPTNQTLQSIVLNAASPEPSVQLSAVQAARKLLSSD 222

Query: 108 KQPPIDNIIRAGLIPKFVSFLGKTDCSPIQFESAWALTNIASGTSEQTKAVVDGGAIPAF 167
           + PPID++I +G++P  V  L + DC  +QFE+AWALTNIASGTS QT+AVV+  A+P F
Sbjct: 221 RNPPIDDLISSGILPILVKCLARDDCPSLQFEAAWALTNIASGTSAQTQAVVNAEAVPYF 42

Query: 168 ISLLASPHAHISE 180
           + LL SPH ++ E
Sbjct: 41  LRLLQSPHQNVCE 3

 Score = 33.5 bits (75), Expect(2) = 2e-32,   Method: Composition-based stats.
 Identities = 14/21 (66%), Positives = 17/21 (80%)
 Frame = -3

Query: 27  MRRRRIEVNVELRKAKKDEQM 47
           MRRRR EV VELRK K+D+ +
Sbjct: 445 MRRRRTEVTVELRKNKRDQHI 383

 Score = 40.0 bits (92), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 21/68 (30%), Positives = 39/68 (57%), Gaps = 2/68 (2%)
 Frame = -2

Query: 346 NPKTNIQKEATWTMSNI-TAGRQDQIQQVVNHGLVPFLVGVLSKADFKT-QKEAAWAITN 403
           +P+ ++Q  A      + ++ R   I  +++ G++P LV  L++ D  + Q EAAWA+TN
Sbjct: 284 SPEPSVQLSAVQAARKLLSSDRNPPIDDLISSGILPILVKCLARDDCPSLQFEAAWALTN 105

Query: 404 YTSGGTVE 411
             SG + +
Sbjct: 104 IASGTSAQ 81

 Score = 35.8 bits (81), Expect = 0.041,   Method: Compositional matrix adjust.
 Identities = 19/57 (33%), Positives = 30/57 (52%), Gaps = 1/57 (1%)
 Frame = -2

Query: 331 VIDAGALAVFPSLLTNPKT-NIQKEATWTMSNITAGRQDQIQQVVNHGLVPFLVGVL 386
           +I +G L +    L      ++Q EA W ++NI +G   Q Q VVN   VP+ + +L
Sbjct: 200 LISSGILPILVKCLARDDCPSLQFEAAWALTNIASGTSAQTQAVVNAEAVPYFLRLL 30
>06510
          Length = 2037

 Score =  122 bits (305), Expect = 5e-28,   Method: Compositional matrix adjust.
 Identities = 127/503 (25%), Positives = 222/503 (44%), Gaps = 16/503 (3%)
 Frame = -1

Query: 16   RFKNKGKDSTEMRRRRIEVNVELRKAKKDEQMLKRRNVSSFPDDATSPLQENRNNQGTVN 75
            + K+       +R ++ E  +E+RK+K+D +   +R V     +   P       +    
Sbjct: 1776 KHKHSAPSVQALRNKQRESQIEIRKSKRDRKFNSKR-VRLGDAEKEEPCISLEETEAVCR 1600

Query: 76   WSVEDIVKGINSNNLESQLQA--TQAARKLLSREKQPPIDNIIRAGLIPKFVSFLGKTDC 133
               E + KG N+ +   +L+   TQ    +   +    +DN ++        S +G    
Sbjct: 1599 ---ELVQKGTNTMDCLLKLRRAFTQGPEYI---DMLFTVDNCLQ--------SLVGILTG 1462

Query: 134  SPIQFES--AWALTNIASGTSEQTKAVVDGGAIPAFISLLASPHAHISEQAVWALGNIAG 191
            S I+ +   AW LTN A+G  +   A+    A P  I+ ++     + +Q  W LGNIAG
Sbjct: 1461 SNIEHQEQVAWCLTNAATGRPQHVLALAKAAA-PYCITFISGSSPMLQDQCAWTLGNIAG 1285

Query: 192  DGSAFRDLVIKHGAIXXXXXXXXXXXXSTLACGYLRNLTWTLSNLCRNKNPAPPLDAVEQ 251
            D    R L+   G +            ST AC  +++  + +SNL    +      A   
Sbjct: 1284 DNVECRRLLHSMGCLSPLITLLES---STPAC--VKSAAFAISNLIGELHDIANEAAQGG 1120

Query: 252  ILPTLVRLLHHND--PEVLADSCWAISYLTDGPNERIEMVVKKGVVPQLVKLLGATELP- 308
            +L  L+RLL   D   +VL++  W ++YLT+ P+   +M+   G +P +V ++    +  
Sbjct: 1119 LLVVLLRLLQKTDLXDDVLSELGWVVTYLTNSPDIVTQMMTM-GFLPLIVDIIVHVAMTG 943

Query: 309  ------IVTPALRAIGNIVTGTDEQTQKVIDAGALA-VFPSLLTNPKTNIQKEATWTMSN 361
                  + TP LRA+GNI  G D+ +    +   L      LL  P  ++ KE TW MSN
Sbjct: 942  QIKTGEVATPMLRALGNICCGPDDYSLMACENPRLMPAILRLLECPLPHVVKETTWVMSN 763

Query: 362  ITAGRQDQIQQVVNHGLVPFLVGVLSKAD--FKTQKEAAWAITNYTSGGTVEQIVYLVHC 419
            +T+     + Q V +G  P L G+LS  D     Q E  + + N  S G       + H 
Sbjct: 762  MTSDYN--VSQSVAYG--PMLPGLLSLLDKGHDVQVETMYTLCNMASHGETTSKELVRH- 598

Query: 420  GIIEPLMNLLSAKDTKIIQVILDAISNIFQAAEKLGETEKLSIMIEECGGLDKIEALQRH 479
            G +  + +LL + D +++ + L     + +  E          + EECGG+  ++ L+ H
Sbjct: 597  GAMARVASLLKSMDLELLHMALAFCETVLRYCEDA------RFVFEECGGVTSLDRLETH 436

Query: 480  ENESVYKASLNLIEKYFSVEEEE 502
             N  +  A+  +++ YF  + E+
Sbjct: 435  TNTDIQTAAQEIMDTYFGHDAED 367
>15699
          Length = 1004

 Score = 98.6 bits (244), Expect = 6e-21,   Method: Compositional matrix adjust.
 Identities = 58/133 (43%), Positives = 79/133 (59%), Gaps = 11/133 (8%)
 Frame = -3

Query: 408  GTVEQIVYLVHCGIIEPLMNLLSAKDTKIIQVILDAISNIFQAAEKLGETEK-------- 459
            G+ EQI +LV  G I PL +LL+  D+KI+ V L  + NI     +LGE +         
Sbjct: 1002 GSPEQIRFLVEQGCISPLCDLLTVMDSKIVMVALSGLENIL----RLGEQDSKFNNAVNP 835

Query: 460  LSIMIEECGGLDKIEALQRHENESVYKASLNLIEKYFSVEEEEDQNVVP--ETTSEGFAF 517
             ++MIEEC GLDKIE LQ HEN  +YK S  +IE+YFS  E+ED+ + P  +  S+ F F
Sbjct: 834  YAVMIEECYGLDKIEFLQSHENREIYKKSFEIIERYFST-EDEDKVLAPNLDENSQQFQF 658

Query: 518  QVQDGAP-GTFNF 529
              ++ AP G F F
Sbjct: 657  GAEEKAPSGGFQF 619
>22653
          Length = 1347

 Score = 41.6 bits (96), Expect = 8e-04,   Method: Compositional matrix adjust.
 Identities = 47/206 (22%), Positives = 87/206 (42%), Gaps = 10/206 (4%)
 Frame = +3

Query: 256 LVRLLHHNDPEVLADSCWAISYLTDGPNERIEMVVK-KGVVPQLVKLLGATELPIVTPAL 314
           L  LL + +P+V A + WAI    +   +  EMV    G +  +V LL + +  ++    
Sbjct: 3   LWSLLKNQNPDVQASAAWAICPCIENAKDAGEMVRSFVGGLELIVSLLKSEDKEVLAAVC 182

Query: 315 RAIGNIVTGTDEQTQKVI-DAGALAVFP--SLLTNPKTN------IQKEATWTMSNITAG 365
            AI NI    DE+   VI D G + +    +L T+ K        I +   W  +    G
Sbjct: 183 AAIANI--AKDEENLAVITDHGVVPMLAKLTLTTDDKLRQHLAEAIARCCNWGNNRTAFG 356

Query: 366 RQDQIQQVVNHGLVPFLVGVLSKADFKTQKEAAWAITNYTSGGTVEQIVYLVHCGIIEPL 425
           +++ +  +V +         L   D    +  A A+  +      E  + +   G+++PL
Sbjct: 357 KENAVAPLVRY---------LKSKDENVHRSTARAL--FQLSKNPENCITMHEAGVVQPL 503

Query: 426 MNLLSAKDTKIIQVILDAISNIFQAA 451
           + ++ + D  + +     ISNI + A
Sbjct: 504 LKMVGSADDDLQESSAGCISNIRRLA 581
>09672
          Length = 1963

 Score = 40.0 bits (92), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 37/140 (26%), Positives = 64/140 (45%), Gaps = 10/140 (7%)
 Frame = -2

Query: 313  ALRAIGNIVTGTDEQTQKVIDAGALAVFPSLLTNPKTNIQKEATWTMSNITAGRQDQI-- 370
            A+ A G+I+ G D +  K I   A+ +   LLT+P   ++  A WT+     GR  ++  
Sbjct: 1854 AVMAFGSILEGPDSEKLKPIVEQAMPMLIELLTDPSVVVRDTAAWTV-----GRVCEMLP 1690

Query: 371  QQVVNHGLVPFLVGVLSK---ADFKTQKEAAWAITN-----YTSGGTVEQIVYLVHCGII 422
            + V+N   +  L+G L K   A+ +      WA ++     Y S  T ++I         
Sbjct: 1689 EAVINENCLNPLLGALIKGLEAEPRVASNICWAFSSLAEAAYESADTADEIS-------- 1534

Query: 423  EPLMNLLSAKDTKIIQVILD 442
            EP    LS+    ++Q +L+
Sbjct: 1533 EPETYCLSSYFETMVQRLLE 1474
>05045
          Length = 2700

 Score = 30.8 bits (68), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 24/92 (26%), Positives = 39/92 (42%), Gaps = 7/92 (7%)
 Frame = +1

Query: 122 PKFVSFLG-------KTDCSPIQFESAWALTNIASGTSEQTKAVVDGGAIPAFISLLASP 174
           P F SFL        +T  +  +  +   L  +     E T A VD    P F+ ++   
Sbjct: 310 PFFSSFLTDLLKRLKQTSSTAEKSFAVGTLAEVIESIGETTIAFVDT-LYPVFLRMVKEE 486

Query: 175 HAHISEQAVWALGNIAGDGSAFRDLVIKHGAI 206
              +   AV+ALG +A +G     ++ +HG I
Sbjct: 487 DDEVRSNAVFALGMLAANGG--EKMIARHGDI 576
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|86198316|ref|NP_033917.2| protein disulfide isomerase
associated 4 [Mus musculus]
         (641 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

06936                                                                 317   7e-87
03582                                                                 119   2e-49
28335                                                                 121   8e-28
30644                                                                  62   4e-17
35861                                                                  83   3e-16
21509                                                                  57   4e-15
04510                                                                  78   1e-14
18455                                                                  78   1e-14
14392                                                                  60   3e-09
35310                                                                  59   6e-09
07257                                                                  58   1e-08
18943                                                                  54   6e-08
36159                                                                  55   8e-08
15159                                                                  51   1e-06
04779                                                                  45   1e-04
09979                                                                  30   2.8  
>06936
          Length = 2198

 Score =  317 bits (813), Expect = 7e-87,   Method: Compositional matrix adjust.
 Identities = 180/467 (38%), Positives = 276/467 (59%), Gaps = 9/467 (1%)
 Frame = +3

Query: 175 TLSLTKDNFDDVVNNADIILVEFYAPWCGHCKKLAPEYEKAAKELSKRSPPIPLAKVDAT 234
            L L K +F   +    ++LVEF+APWCGHCKKLAP+YE AA  L K  PP+PLAKVD T
Sbjct: 150 VLDLKKSDFQSTIEKHSLMLVEFFAPWCGHCKKLAPQYELAATALLKNDPPVPLAKVDCT 329

Query: 235 EQTDLAKRFDVSGYPTLKIFRKGRPF-DYNGPREKYGIVDYMIEQSGPPSKEILTLKQVQ 293
           E+TD+  ++ VSGYPTLK+FR G    DY+GPR+K GIV YM + +GP SKE+ ++++ +
Sbjct: 330 EETDVCSKYGVSGYPTLKVFRGGEVNKDYDGPRDKDGIVKYMAKMAGPTSKELKSVEEYE 509

Query: 294 EFL-KDGDDVVIIGLFQGDGDPAYLQYQDAANNLREDYKFHHTFSPEIAKFLKVSLGKLV 352
           +FL +DG    ++G F G         +  A++  +  +F +T S E+ +  K    ++V
Sbjct: 510 KFLSRDGS--CVVGFFTGANSGMADTLKKVADS-EDGLRFGYTTSSEVLEKAKYK-DEIV 677

Query: 353 LTHPEKFQSKYEPRFHVMDVQGSTEASAIKDYVVKHALPLVGHRKTSNDAKRYSKRPLVV 412
           L  P+K  +K+E     +   G   +  IK ++ + +  L   R   N A    K+P+V+
Sbjct: 678 LFRPQKMANKFEDT--AVKFTGDANSHNIKKFLKEESFGLCALRTMDNAAD--FKKPVVI 845

Query: 413 VYYSVDFSFDYRAATQFWRNKVLEVAKDFPE----YTFAIADEEDYATEVKDLGLSESGE 468
            ++ VD+  + +  + +WRN+V++V K   +      FA++++ ++  E+ + GL E+ +
Sbjct: 846 AFFDVDYVKNAK-GSNYWRNRVMKVGKKLRDEGLKINFAVSNKNEFDNELVECGLKEAVD 1022

Query: 469 DVNAAIL---DESGKKFAMEPEEFDSDTLREFVTAFKKGKLKPVIKSQXXXXXXXXXXXX 525
             +   +   ++  +KF M+ +EF  DT  +FV     GKL+  +KS+            
Sbjct: 1023ASDKPAICAYNDKNQKFKMD-QEFAMDTFEQFVRDMLDGKLEAYMKSEPVPDNSENAVKV 1199

Query: 526 XXXXTFDAIVMDPKKDVLIEFYAPWCGHCKQLEPIYTSLGKKYKGQKDLVIAKMDATAND 585
                F+ +V DP+KDVLIEFYAPWCGHCK L P Y  L +K K + ++VIAKMDATAND
Sbjct: 1200AVGRNFEELVNDPEKDVLIEFYAPWCGHCKTLAPKYDELAEKLKNEPEIVIAKMDATAND 1379

Query: 586 ITNDQYKVEGFPTIYFAPSGDKKNPIKFEGGNRDLEHLSKFIDEHAT 632
           +    Y V GFPT+YFAP G K +P K+EGG R++    K++ + AT
Sbjct: 1380VP-PPYDVRGFPTLYFAPKGSKSSPKKYEGG-REVNDFVKYLAKEAT 1514

 Score =  102 bits (255), Expect = 3e-22,   Method: Compositional matrix adjust.
 Identities = 46/108 (42%), Positives = 71/108 (65%), Gaps = 1/108 (0%)
 Frame = +3

Query: 60  VWVLNDGNFDNFVADKDTVLLEFYAPWCGHCKQFAPEYEKIASTLKDNDPPIAVAKIDAT 119
           V  L   +F + +     +L+EF+APWCGHCK+ AP+YE  A+ L  NDPP+ +AK+D T
Sbjct: 150 VLDLKKSDFQSTIEKHSLMLVEFFAPWCGHCKKLAPQYELAATALLKNDPPVPLAKVDCT 329

Query: 120 SASMLASKFDVSGYPTIKILKKGQA-VDYDGSRTQEEIVAKVREVSQP 166
             + + SK+ VSGYPT+K+ + G+   DYDG R ++ IV  + +++ P
Sbjct: 330 EETDVCSKYGVSGYPTLKVFRGGEVNKDYDGPRDKDGIVKYMAKMAGP 473

 Score = 82.0 bits (201), Expect = 7e-16,   Method: Compositional matrix adjust.
 Identities = 46/104 (44%), Positives = 63/104 (60%), Gaps = 4/104 (3%)
 Frame = +3

Query: 58   NGVWVLNDGNFDNFVADKDT-VLLEFYAPWCGHCKQFAPEYEKIASTLKDNDPPIAVAKI 116
            N V V    NF+  V D +  VL+EFYAPWCGHCK  AP+Y+++A  LK N+P I +AK+
Sbjct: 1185 NAVKVAVGRNFEELVNDPEKDVLIEFYAPWCGHCKTLAPKYDELAEKLK-NEPEIVIAKM 1361

Query: 117  DATSASMLASKFDVSGYPTIKILKKGQAVD---YDGSRTQEEIV 157
            DAT A+ +   +DV G+PT+    KG       Y+G R   + V
Sbjct: 1362 DAT-ANDVPPPYDVRGFPTLYFAPKGSKSSPKKYEGGREVNDFV 1490
>03582
          Length = 1967

 Score =  119 bits (297), Expect(2) = 2e-49,   Method: Compositional matrix adjust.
 Identities = 106/365 (29%), Positives = 174/365 (47%), Gaps = 8/365 (2%)
 Frame = +3

Query: 277 EQSGPPSKEILTLKQVQEFLKDGDDVVIIGLFQGDGDPAYLQYQDAANNLREDYKFHHTF 336
           E++GPP++++    + + F  + D+VV+IG F+       + + +AA  + +D  F  T 
Sbjct: 423 EKTGPPAEDLKDKDEAKAF-AEKDEVVVIGFFKDQKSEGAVAFTEAAAGI-DDIPFGITS 596

Query: 337 SPEIAKFLKVSLGKLVLTHPEKFQSKYEPRFHVMDVQGSTEASAIKDYVVKHALPLVGHR 396
                K  K+    +VL   +KF    E R    D +G  E +AI  +V  + LPLV   
Sbjct: 597 DESAFKEYKMDKDGIVLL--KKFD---EGR---NDFEGDFEPAAIIKHVRDNQLPLVVEF 752

Query: 397 KTSNDAKRYSK--RPLVVVYYSVDFSFD----YRAATQFWRNKVLEVAKDFPEYTFAIAD 450
              +  K +    +  ++++   D   D    ++AA   ++ KVL        + +   D
Sbjct: 753 TQESAQKIFGGEVKNHILLFLKKDGGEDTIEKFKAAAGDFKGKVL--------FIYLDTD 908

Query: 451 EEDYATEVKDLGL-SESGEDVNAAILDESGKKFAMEPEEFDSDTLREFVTAFKKGKLKPV 509
           + +     +  GL  E    V    L E   K+  E  + D++T+++FV  F  GKL   
Sbjct: 909 DAENGRITEFFGLKDEEIPAVRLIQLAEDMTKYKPESADLDTETIKKFVQDFLDGKLNAH 1088

Query: 510 IKSQXXXXX-XXXXXXXXXXXTFDAIVMDPKKDVLIEFYAPWCGHCKQLEPIYTSLGKKY 568
           + S+                  F  + +D  K V +EFYAPWCGHCKQL PI+  L  K+
Sbjct: 1089LMSEDVPSDWDAKPVKVLVGKNFKEVALDKTKGVFVEFYAPWCGHCKQLAPIWDELADKF 1268

Query: 569 KGQKDLVIAKMDATANDITNDQYKVEGFPTIYFAPSGDKKNPIKFEGGNRDLEHLSKFID 628
             + D+VIAKMD+TAN+I  ++ KV+ FPT+ + P  D    I +  G R L+   KF++
Sbjct: 1269TDKADVVIAKMDSTANEI--EEVKVQSFPTLKYFPK-DSDEVIDY-NGERTLDAFVKFVE 1436

Query: 629 EHATK 633
              T+
Sbjct: 1437SGGTE 1451

 Score = 95.9 bits (237), Expect(2) = 2e-49,   Method: Compositional matrix adjust.
 Identities = 44/75 (58%), Positives = 51/75 (68%)
 Frame = +2

Query: 178 LTKDNFDDVVNNADIILVEFYAPWCGHCKKLAPEYEKAAKELSKRSPPIPLAKVDATEQT 237
           LT  NFD  V   + +LVEFYAPWCGHCK LAPEY KAA+ L   +  + LAKVDAT +T
Sbjct: 128 LTTKNFDSFVKENEFVLVEFYAPWCGHCKALAPEYAKAAQTLKDENSDVKLAKVDATIET 307

Query: 238 DLAKRFDVSGYPTLK 252
            L +   V GYPTLK
Sbjct: 308 SLGENMGVRGYPTLK 352

 Score = 99.0 bits (245), Expect = 5e-21,   Method: Compositional matrix adjust.
 Identities = 49/111 (44%), Positives = 66/111 (59%)
 Frame = +2

Query: 59  GVWVLNDGNFDNFVADKDTVLLEFYAPWCGHCKQFAPEYEKIASTLKDNDPPIAVAKIDA 118
           GV+VL   NFD+FV + + VL+EFYAPWCGHCK  APEY K A TLKD +  + +AK+DA
Sbjct: 116 GVYVLTTKNFDSFVKENEFVLVEFYAPWCGHCKALAPEYAKAAQTLKDENSDVKLAKVDA 295

Query: 119 TSASMLASKFDVSGYPTIKILKKGQAVDYDGSRTQEEIVAKVREVSQPDWT 169
           T  + L     V GYPT+K     + ++       + + A  R+    DWT
Sbjct: 296 TIETSLGENMGVRGYPTLKFSVMEKILNIPAGAKLQTLSAG*RK----DWT 436

 Score = 70.5 bits (171), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 40/101 (39%), Positives = 57/101 (56%), Gaps = 3/101 (2%)
 Frame = +3

Query: 60   VWVLNDGNFDNFVADKDT-VLLEFYAPWCGHCKQFAPEYEKIASTLKDNDPPIAVAKIDA 118
            V VL   NF     DK   V +EFYAPWCGHCKQ AP ++++A    D    + +AK+D+
Sbjct: 1131 VKVLVGKNFKEVALDKTKGVFVEFYAPWCGHCKQLAPIWDELADKFTDK-ADVVIAKMDS 1307

Query: 119  TSASMLASKFDVSGYPTIKILKK--GQAVDYDGSRTQEEIV 157
            T+  +   K  V  +PT+K   K   + +DY+G RT +  V
Sbjct: 1308 TANEIEEVK--VQSFPTLKYFPKDSDEVIDYNGERTLDAFV 1424

 Score = 66.6 bits (161), Expect = 3e-11,   Method: Compositional matrix adjust.
 Identities = 42/117 (35%), Positives = 63/117 (53%), Gaps = 3/117 (2%)
 Frame = +3

Query: 167  DWTPPPEVTLSLTKDNFDDV-VNNADIILVEFYAPWCGHCKKLAPEYEKAAKELSKRSPP 225
            DW   P     L   NF +V ++    + VEFYAPWCGHCK+LAP +++ A + + ++  
Sbjct: 1113 DWDAKP--VKVLVGKNFKEVALDKTKGVFVEFYAPWCGHCKQLAPIWDELADKFTDKA-D 1283

Query: 226  IPLAKVDATEQTDLAKRFDVSGYPTLKIFRK--GRPFDYNGPREKYGIVDYMIEQSG 280
            + +AK+D+T   +  +   V  +PTLK F K      DYNG R     V + +E  G
Sbjct: 1284 VVIAKMDST--ANEIEEVKVQSFPTLKYFPKDSDEVIDYNGERTLDAFVKF-VESGG 1445

 Score = 61.6 bits (148), Expect = 9e-10,   Method: Compositional matrix adjust.
 Identities = 31/73 (42%), Positives = 44/73 (60%), Gaps = 1/73 (1%)
 Frame = +2

Query: 531 FDAIVMDPKKDVLIEFYAPWCGHCKQLEPIYTSLGKKYKGQK-DLVIAKMDATANDITND 589
           FD+ V +  + VL+EFYAPWCGHCK L P Y    +  K +  D+ +AK+DAT      +
Sbjct: 143 FDSFVKE-NEFVLVEFYAPWCGHCKALAPEYAKAAQTLKDENSDVKLAKVDATIETSLGE 319

Query: 590 QYKVEGFPTIYFA 602
              V G+PT+ F+
Sbjct: 320 NMGVRGYPTLKFS 358
>28335
          Length = 601

 Score =  121 bits (304), Expect = 8e-28,   Method: Compositional matrix adjust.
 Identities = 64/132 (48%), Positives = 84/132 (63%)
 Frame = -2

Query: 505 KLKPVIKSQXXXXXXXXXXXXXXXXTFDAIVMDPKKDVLIEFYAPWCGHCKQLEPIYTSL 564
           +++P +KSQ                TFD IV +PKKDVLIEFYAPWCGHC+QLEP Y  L
Sbjct: 600 EIQPYLKSQPIPQNEEGPVKTAVGRTFDKIVNNPKKDVLIEFYAPWCGHCQQLEPKYNEL 421

Query: 565 GKKYKGQKDLVIAKMDATANDITNDQYKVEGFPTIYFAPSGDKKNPIKFEGGNRDLEHLS 624
               K + D+V AK+DATAND T   Y+V+GFP IYF+P   K+ P K+E G+R+++ + 
Sbjct: 420 ATLLKDEPDIVXAKIDATAND-TPTPYEVKGFPAIYFSPKRFKEFPKKYE-GDREVDAML 247

Query: 625 KFIDEHATKRSR 636
           K+I   AT   R
Sbjct: 246 KYIAREATSELR 211

 Score = 71.6 bits (174), Expect = 9e-13,   Method: Compositional matrix adjust.
 Identities = 36/71 (50%), Positives = 49/71 (69%), Gaps = 1/71 (1%)
 Frame = -2

Query: 67  NFDNFVAD-KDTVLLEFYAPWCGHCKQFAPEYEKIASTLKDNDPPIAVAKIDATSASMLA 125
            FD  V + K  VL+EFYAPWCGHC+Q  P+Y ++A+ LKD +P I  AKIDAT A+   
Sbjct: 525 TFDKIVNNPKKDVLIEFYAPWCGHCQQLEPKYNELATLLKD-EPDIVXAKIDAT-ANDTP 352

Query: 126 SKFDVSGYPTI 136
           + ++V G+P I
Sbjct: 351 TPYEVKGFPAI 319

 Score = 67.8 bits (164), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 41/103 (39%), Positives = 58/103 (56%), Gaps = 5/103 (4%)
 Frame = -2

Query: 182 NFDDVVNNADI-ILVEFYAPWCGHCKKLAPEYEKAAKELSKRSPPIPLAKVDATEQTDLA 240
            FD +VNN    +L+EFYAPWCGHC++L P+Y + A  L K  P I  AK+DAT   D  
Sbjct: 525 TFDKIVNNPKKDVLIEFYAPWCGHCQQLEPKYNELAT-LLKDEPDIVXAKIDAT-ANDTP 352

Query: 241 KRFDVSGYPTLKIFRKGR----PFDYNGPREKYGIVDYMIEQS 279
             ++V G+P +  F   R    P  Y G RE   ++ Y+  ++
Sbjct: 351 TPYEVKGFPAI-YFSPKRFKEFPKKYEGDREVDAMLKYIAREA 226
>30644
          Length = 845

 Score = 62.4 bits (150), Expect(2) = 4e-17,   Method: Compositional matrix adjust.
 Identities = 29/100 (29%), Positives = 50/100 (50%), Gaps = 8/100 (8%)
 Frame = -1

Query: 116 IDATSASMLASKFDVSGYPTIKILKKGQA-VDYDGSRTQEEIVAKVREVSQ-------PD 167
           +D      + ++++++G+PT+   +KG+    Y G   ++ I++ +             +
Sbjct: 305 VDKPHMKGVQAQYNITGFPTLYYFEKGKLKYRYGGENNKDGIISWLSNPKPPEEPKKEAE 126

Query: 168 WTPPPEVTLSLTKDNFDDVVNNADIILVEFYAPWCGHCKK 207
           W+  P     L   NFDD +     +LV FYAPWCGHCKK
Sbjct: 125 WSEEPSEVAHLEDSNFDDFLKQHPSVLVMFYAPWCGHCKK 6

 Score = 44.3 bits (103), Expect(2) = 4e-17,   Method: Compositional matrix adjust.
 Identities = 18/47 (38%), Positives = 26/47 (55%)
 Frame = -3

Query: 64  NDGNFDNFVADKDTVLLEFYAPWCGHCKQFAPEYEKIASTLKDNDPP 110
           +DG       DK   L+ FYAPWCG+CK+  P++   A+ +K    P
Sbjct: 459 DDGLTKLLKKDKSAALVMFYAPWCGYCKRMKPDFAAAATEVKGRGQP 319

 Score = 47.4 bits (111), Expect(2) = 2e-09,   Method: Compositional matrix adjust.
 Identities = 17/32 (53%), Positives = 23/32 (71%)
 Frame = -3

Query: 194 LVEFYAPWCGHCKKLAPEYEKAAKELSKRSPP 225
           LV FYAPWCG+CK++ P++  AA E+  R  P
Sbjct: 414 LVMFYAPWCGYCKRMKPDFAAAATEVKGRGQP 319

 Score = 32.7 bits (73), Expect(2) = 2e-09,   Method: Compositional matrix adjust.
 Identities = 14/46 (30%), Positives = 26/46 (56%), Gaps = 1/46 (2%)
 Frame = -1

Query: 231 VDATEQTDLAKRFDVSGYPTLKIFRKGR-PFDYNGPREKYGIVDYM 275
           VD      +  +++++G+PTL  F KG+  + Y G   K GI+ ++
Sbjct: 305 VDKPHMKGVQAQYNITGFPTLYYFEKGKLKYRYGGENNKDGIISWL 168

 Score = 48.1 bits (113), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 18/30 (60%), Positives = 23/30 (76%)
 Frame = -1

Query: 63 LNDGNFDNFVADKDTVLLEFYAPWCGHCKQ 92
          L D NFD+F+    +VL+ FYAPWCGHCK+
Sbjct: 95 LEDSNFDDFLKQHPSVLVMFYAPWCGHCKK 6

 Score = 42.0 bits (97), Expect(2) = 2e-05,   Method: Compositional matrix adjust.
 Identities = 14/33 (42%), Positives = 23/33 (69%)
 Frame = -3

Query: 539 KKDVLIEFYAPWCGHCKQLEPIYTSLGKKYKGQ 571
           K   L+ FYAPWCG+CK+++P + +   + KG+
Sbjct: 426 KSAALVMFYAPWCGYCKRMKPDFAAAATEVKGR 328

 Score = 24.6 bits (52), Expect(2) = 2e-05,   Method: Compositional matrix adjust.
 Identities = 9/19 (47%), Positives = 12/19 (63%)
 Frame = -1

Query: 590 QYKVEGFPTIYFAPSGDKK 608
           QY + GFPT+Y+   G  K
Sbjct: 272 QYNITGFPTLYYFEKGKLK 216

 Score = 36.6 bits (83), Expect = 0.035,   Method: Compositional matrix adjust.
 Identities = 12/15 (80%), Positives = 14/15 (93%)
 Frame = -1

Query: 542 VLIEFYAPWCGHCKQ 556
           VL+ FYAPWCGHCK+
Sbjct: 50  VLVMFYAPWCGHCKK 6
>35861
          Length = 850

 Score = 83.2 bits (204), Expect = 3e-16,   Method: Compositional matrix adjust.
 Identities = 46/125 (36%), Positives = 65/125 (52%), Gaps = 1/125 (0%)
 Frame = +3

Query: 481 KFAMEPEEFDSDTLREFVTAFKKGKLKPVIKSQXXXXXXXXX-XXXXXXXTFDAIVMDPK 539
           K+  E  + D+ T+ +FV  F  GKLKP +KS+                  F  + +D  
Sbjct: 447 KYKPESGDLDTATISKFVQDFMDGKLKPHLKSEEVPEDWDAKPVKVLVSKNFKEVALDKS 626

Query: 540 KDVLIEFYAPWCGHCKQLEPIYTSLGKKYKGQKDLVIAKMDATANDITNDQYKVEGFPTI 599
           KDV +EFYAPWCGHCKQL PI+  LG+K++   D+VIAK     N +   +    G P +
Sbjct: 627 KDVFVEFYAPWCGHCKQLVPIWDELGEKFQDSDDVVIAK-----NGLHGQRSGGGGHPEL 791

Query: 600 YFAPS 604
              P+
Sbjct: 792 PHPPN 806

 Score = 52.0 bits (123), Expect = 7e-07,   Method: Compositional matrix adjust.
 Identities = 24/55 (43%), Positives = 33/55 (60%), Gaps = 1/55 (1%)
 Frame = +3

Query: 62  VLNDGNFDNFVADKDT-VLLEFYAPWCGHCKQFAPEYEKIASTLKDNDPPIAVAK 115
           VL   NF     DK   V +EFYAPWCGHCKQ  P ++++    +D+D  + +AK
Sbjct: 582 VLVSKNFKEVALDKSKDVFVEFYAPWCGHCKQLVPIWDELGEKFQDSD-DVVIAK 743

 Score = 46.6 bits (109), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 21/54 (38%), Positives = 32/54 (59%), Gaps = 1/54 (1%)
 Frame = +3

Query: 167 DWTPPPEVTLSLTKDNFDDV-VNNADIILVEFYAPWCGHCKKLAPEYEKAAKEL 219
           DW   P     L   NF +V ++ +  + VEFYAPWCGHCK+L P +++  ++ 
Sbjct: 558 DWDAKP--VKVLVSKNFKEVALDKSKDVFVEFYAPWCGHCKQLVPIWDELGEKF 713
>21509
          Length = 754

 Score = 52.4 bits (124), Expect(2) = 4e-15,   Method: Compositional matrix adjust.
 Identities = 37/126 (29%), Positives = 54/126 (42%), Gaps = 12/126 (9%)
 Frame = -3

Query: 61  WVLNDGNFDNFVADKDTVLLEFY-----------APWCGHCKQFAPEYEKIASTLKDNDP 109
           W L    FD FV+   +VL+ F            + W G C        K+         
Sbjct: 719 WFLTKDTFDTFVSTHSSVLVMFTPHGADIVKNEASVWRGCCHH---SRAKLG-------- 573

Query: 110 PIAVAKIDATSASMLASKFDVSGYPTIKILKKGQ-AVDYDGSRTQEEIVAKVREVSQPDW 168
             AVA +DAT    L +K+DV GYPT+K  K G+ A +Y G R+ +  V+ +++      
Sbjct: 572 --AVAAVDATLDPELGNKYDVKGYPTLKYFKDGKLAFEYSGGRSSDAFVSFMKKAGAGPT 399

Query: 169 TPPPEV 174
            P P  
Sbjct: 398 LPTPRT 381

 Score = 47.4 bits (111), Expect(2) = 4e-15,   Method: Compositional matrix adjust.
 Identities = 20/39 (51%), Positives = 23/39 (58%)
 Frame = -1

Query: 178 LTKDNFDDVVNNADIILVEFYAPWCGHCKKLAPEYEKAA 216
           LT   F+  +      LV FYAPWCGHCKK+ P Y  AA
Sbjct: 346 LTDATFESFIAANRRTLVMFYAPWCGHCKKMKPAYMAAA 230

 Score = 57.0 bits (136), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 36/107 (33%), Positives = 51/107 (47%), Gaps = 1/107 (0%)
 Frame = -3

Query: 178 LTKDNFDDVVNNADIILVEFYAPWCGHCKKLAPEYEKAAKELSKRSPPIPLAKVDATEQT 237
           LTKD FD  V+    +LV F        K  A  +         R+    +A VDAT   
Sbjct: 713 LTKDTFDTFVSTHSSVLVMFTPHGADIVKNEASVWRGCCHH--SRAKLGAVAAVDATLDP 540

Query: 238 DLAKRFDVSGYPTLKIFRKGR-PFDYNGPREKYGIVDYMIEQSGPPS 283
           +L  ++DV GYPTLK F+ G+  F+Y+G R     V +M +    P+
Sbjct: 539 ELGNKYDVKGYPTLKYFKDGKLAFEYSGGRSSDAFVSFMKKAGAGPT 399

 Score = 50.8 bits (120), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 19/39 (48%), Positives = 24/39 (61%)
 Frame = -1

Query: 63  LNDGNFDNFVADKDTVLLEFYAPWCGHCKQFAPEYEKIA 101
           L D  F++F+A     L+ FYAPWCGHCK+  P Y   A
Sbjct: 346 LTDATFESFIAANRRTLVMFYAPWCGHCKKMKPAYMAAA 230

 Score = 43.9 bits (102), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 15/34 (44%), Positives = 25/34 (73%)
 Frame = -1

Query: 530 TFDAIVMDPKKDVLIEFYAPWCGHCKQLEPIYTS 563
           TF++ +   ++  L+ FYAPWCGHCK+++P Y +
Sbjct: 334 TFESFIAANRR-TLVMFYAPWCGHCKKMKPAYMA 236

 Score = 28.1 bits (61), Expect(2) = 0.052,   Method: Compositional matrix adjust.
 Identities = 9/13 (69%), Positives = 10/13 (76%)
 Frame = -2

Query: 544 IEFYAPWCGHCKQ 556
              YAPWCGHCK+
Sbjct: 663 CHVYAPWCGHCKK 625

 Score = 26.6 bits (57), Expect(2) = 0.052,   Method: Compositional matrix adjust.
 Identities = 15/42 (35%), Positives = 25/42 (59%), Gaps = 1/42 (2%)
 Frame = -3

Query: 576 IAKMDATANDITNDQYKVEGFPTI-YFAPSGDKKNPIKFEGG 616
           +A +DAT +    ++Y V+G+PT+ YF    D K   ++ GG
Sbjct: 569 VAAVDATLDPELGNKYDVKGYPTLKYFK---DGKLAFEYSGG 453
>04510
          Length = 685

 Score = 77.8 bits (190), Expect = 1e-14,   Method: Compositional matrix adjust.
 Identities = 33/57 (57%), Positives = 40/57 (70%)
 Frame = +2

Query: 175 TLSLTKDNFDDVVNNADIILVEFYAPWCGHCKKLAPEYEKAAKELSKRSPPIPLAKV 231
            L L K +F   +    ++LVEF+APWCGHCKKLAP+YE AA  L K  PP+PLAKV
Sbjct: 356 VLDLKKSDFQSTIEKHSLMLVEFFAPWCGHCKKLAPQYELAATALLKNDPPVPLAKV 526

 Score = 66.2 bits (160), Expect = 4e-11,   Method: Compositional matrix adjust.
 Identities = 25/54 (46%), Positives = 37/54 (68%)
 Frame = +2

Query: 63  LNDGNFDNFVADKDTVLLEFYAPWCGHCKQFAPEYEKIASTLKDNDPPIAVAKI 116
           L   +F + +     +L+EF+APWCGHCK+ AP+YE  A+ L  NDPP+ +AK+
Sbjct: 365 LKKSDFQSTIEKHSLMLVEFFAPWCGHCKKLAPQYELAATALLKNDPPVPLAKV 526

 Score = 42.4 bits (98), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 14/20 (70%), Positives = 18/20 (90%)
 Frame = +2

Query: 542 VLIEFYAPWCGHCKQLEPIY 561
           +L+EF+APWCGHCK+L P Y
Sbjct: 410 MLVEFFAPWCGHCKKLAPQY 469
>18455
          Length = 499

 Score = 77.8 bits (190), Expect = 1e-14,   Method: Compositional matrix adjust.
 Identities = 41/112 (36%), Positives = 65/112 (58%), Gaps = 1/112 (0%)
 Frame = +2

Query: 176 LSLTKDNFDDVVNNADIILVEFYAPWCGHCKKLAPEYEKAAKELSKRSPPIPLAKVDATE 235
           + LT+D F   V++ +   V+F+APWC HC++LAP +E+ AK L K  P   ++K+D T+
Sbjct: 149 VDLTEDTFAKHVSSGNH-FVKFFAPWCSHCQRLAPIWEELAKALIKE-PSATISKIDCTQ 322

Query: 236 QTDLAKRFDVSGYPTLKIFRKGRPFD-YNGPREKYGIVDYMIEQSGPPSKEI 286
              + + F+V GYPTL     G+  + Y G R+   +  Y+ +  G PS  I
Sbjct: 323 YRSICQDFEVKGYPTLLWIEDGKKIEKYAGARDMVTLKTYVEKMIGAPSGNI 478

 Score = 64.3 bits (155), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 27/74 (36%), Positives = 47/74 (63%), Gaps = 1/74 (1%)
 Frame = +2

Query: 79  LLEFYAPWCGHCKQFAPEYEKIASTLKDNDPPIAVAKIDATSASMLASKFDVSGYPTIKI 138
            ++F+APWC HC++ AP +E++A  L   +P   ++KID T    +   F+V GYPT+  
Sbjct: 200 FVKFFAPWCSHCQRLAPIWEELAKALI-KEPSATISKIDCTQYRSICQDFEVKGYPTLLW 376

Query: 139 LKKGQAVD-YDGSR 151
           ++ G+ ++ Y G+R
Sbjct: 377 IEDGKKIEKYAGAR 418

 Score = 60.5 bits (145), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 27/87 (31%), Positives = 48/87 (55%)
 Frame = +2

Query: 543 LIEFYAPWCGHCKQLEPIYTSLGKKYKGQKDLVIAKMDATANDITNDQYKVEGFPTIYFA 602
            ++F+APWC HC++L PI+  L K    +    I+K+D T        ++V+G+PT+ + 
Sbjct: 200 FVKFFAPWCSHCQRLAPIWEELAKALIKEPSATISKIDCTQYRSICQDFEVKGYPTLLWI 379

Query: 603 PSGDKKNPIKFEGGNRDLEHLSKFIDE 629
             G K   I+   G RD+  L  ++++
Sbjct: 380 EDGKK---IEKYAGARDMVTLKTYVEK 451
>14392
          Length = 468

 Score = 59.7 bits (143), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 31/76 (40%), Positives = 48/76 (63%)
 Frame = +2

Query: 557 LEPIYTSLGKKYKGQKDLVIAKMDATANDITNDQYKVEGFPTIYFAPSGDKKNPIKFEGG 616
           L PIY  L +K + + D+ I KMDATAND+   ++ V GFPT+++ P   K  P+ + GG
Sbjct: 2   LTPIYEELAEKLQDE-DVAIVKMDATANDVP-PEFNVRGFPTLFWLPKDSKNKPVSYNGG 175

Query: 617 NRDLEHLSKFIDEHAT 632
            R+L+   K+I + A+
Sbjct: 176 -RELDDFIKYIAKEAS 220
>35310
          Length = 601

 Score = 58.9 bits (141), Expect = 6e-09,   Method: Compositional matrix adjust.
 Identities = 57/204 (27%), Positives = 93/204 (45%), Gaps = 7/204 (3%)
 Frame = +3

Query: 289 LKQVQEF--LKDGDDVVIIGLFQGDGDPAYLQYQDAANNLREDYKFHHTFSPEIAKFLKV 346
           LK + +F    D     ++G FQ         +Q  A+    D +F  T  P++ +    
Sbjct: 3   LKDISDFNAFLDRPGTSVVGYFQNVKGYKARTFQKVADTY-GDLRFAFTTDPDLMQHAGY 179

Query: 347 SLGKLVLTHPEKFQSKYEPRFHVMDVQGSTEASAIKDYVVKHALPLVGHRKTSNDAKRYS 406
           S   +VL  P+   SK+E    V    G   A+ ++ ++    L L G R   N  K   
Sbjct: 180 S-DDVVLYRPKVMASKFEESSVVFG--GDLSATTLRFFLDAQKLGLCGLRTPGNAIK--F 344

Query: 407 KRPLVVVYYSVDFSFDYRAATQFWRNKVLEVAKDFPE----YTFAIADEEDYATEVKDLG 462
           K PL V YY VDF  +   +T +WRN+V++V K   +      FA++ + D   +++D G
Sbjct: 345 KTPLFVAYYEVDFERNPSFST-YWRNRVMKVGKKIRDEGNNAHFAVSSKVDLKQDLEDCG 521

Query: 463 LSE-SGEDVNAAILDESGKKFAME 485
           L++  G+       D+  +KF ME
Sbjct: 522 LADYYGDPPVVCAYDQFSRKFKME 593
>07257
          Length = 1477

 Score = 57.8 bits (138), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 29/107 (27%), Positives = 49/107 (45%), Gaps = 3/107 (2%)
 Frame = -3

Query: 188  NNADIILVEFYAPWCGHCKKLAPEYEKAAKELSKRSPPIPLAKVDATEQTDLAKRFDVSG 247
            + AD +LV FYAPWC  C   AP Y   A+      P + +  VD    ++L  RF    
Sbjct: 1304 STADCVLVMFYAPWCHFCANTAPHYNALARAF----PQLEVLAVDTVHFSNLNARFGTVA 1137

Query: 248  YPTLKIFRKGRP---FDYNGPREKYGIVDYMIEQSGPPSKEILTLKQ 291
             P + +F + R    F++   R+ +  + ++   +G  +   + L Q
Sbjct: 1136 VPNIMLFHQSRSAVRFNHT-ERDFHTFLQFIANTTGLEANSSVELSQ 999

 Score = 48.9 bits (115), Expect = 6e-06,   Method: Compositional matrix adjust.
 Identities = 22/72 (30%), Positives = 33/72 (45%)
 Frame = -3

Query: 73   ADKDTVLLEFYAPWCGHCKQFAPEYEKIASTLKDNDPPIAVAKIDATSASMLASKFDVSG 132
            +  D VL+ FYAPWC  C   AP Y  +A       P + V  +D    S L ++F    
Sbjct: 1304 STADCVLVMFYAPWCHFCANTAPHYNALARAF----PQLEVLAVDTVHFSNLNARFGTVA 1137

Query: 133  YPTIKILKKGQA 144
             P I +  + ++
Sbjct: 1136 VPNIMLFHQSRS 1101

 Score = 43.9 bits (102), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 24/100 (24%), Positives = 39/100 (39%)
 Frame = -3

Query: 542  VLIEFYAPWCGHCKQLEPIYTSLGKKYKGQKDLVIAKMDATANDITNDQYKVEGFPTIYF 601
            VL+ FYAPWC  C    P Y +L + +     L +  +D       N ++     P I  
Sbjct: 1289 VLVMFYAPWCHFCANTAPHYNALARAF---PQLEVLAVDTVHFSNLNARFGTVAVPNIML 1119

Query: 602  APSGDKKNPIKFEGGNRDLEHLSKFIDEHATKRSRTKEEL 641
                  ++ ++F    RD     +FI       + +  EL
Sbjct: 1118 F--HQSRSAVRFNHTERDFHTFLQFIANTTGLEANSSVEL 1005
>18943
          Length = 1035

 Score = 42.0 bits (97), Expect(2) = 6e-08,   Method: Compositional matrix adjust.
 Identities = 18/54 (33%), Positives = 33/54 (61%), Gaps = 2/54 (3%)
 Frame = +2

Query: 111 IAVAKIDATSASMLASKFDVSGYPTIKILKKGQAV--DYDGSRTQEEIVAKVRE 162
           +  AK+D      +AS++ +S YPT+K+ + GQ V  ++ G R+ + + A +RE
Sbjct: 281 VLFAKVDCDKEVTIASQYRISKYPTLKLFRNGQMVKKEFRGQRSADALAAFIRE 442

 Score = 33.1 bits (74), Expect(2) = 6e-08,   Method: Compositional matrix adjust.
 Identities = 13/37 (35%), Positives = 19/37 (51%)
 Frame = +3

Query: 63  LNDGNFDNFVADKDTVLLEFYAPWCGHCKQFAPEYEK 99
           LN+ N +  ++  D V + FYA WC   +  AP   K
Sbjct: 129 LNNDNINTIISRNDVVFVNFYADWCRFSQILAPRLMK 239

 Score = 53.9 bits (128), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 38/152 (25%), Positives = 75/152 (49%), Gaps = 15/152 (9%)
 Frame = +2

Query: 202 CGHCKKLA----------PEYEKAAKELSKR-SPP--IPLAKVDATEQTDLAKRFDVSGY 248
           CG C+ L           P +++A++++S+  + P  +  AKVD  ++  +A ++ +S Y
Sbjct: 170 CGVCQLLCRLVSLQSDSGPTFDEASRKISEEFTQPGKVLFAKVDCDKEVTIASQYRISKY 349

Query: 249 PTLKIFRKGRPF--DYNGPREKYGIVDYMIEQSGPPSKEILTLKQVQEFLKDGDDVVIIG 306
           PTLK+FR G+    ++ G R    +  ++ E+      +  TL +++E   D     +IG
Sbjct: 350 PTLKLFRNGQMVKKEFRGQRSADALAAFIREELKDSVVDHNTLDKLEEL--DTKKRQVIG 523

Query: 307 LFQGDGDPAYLQYQDAANNLREDYKFHHTFSP 338
            F+      Y  +   A++LR++  F+    P
Sbjct: 524 YFEAKESDNYKTFLRVASSLRDNCIFNTAVGP 619

 Score = 38.5 bits (88), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 16/48 (33%), Positives = 27/48 (56%)
 Frame = +3

Query: 176 LSLTKDNFDDVVNNADIILVEFYAPWCGHCKKLAPEYEKAAKELSKRS 223
           ++L  DN + +++  D++ V FYA WC   + LAP   K  ++  K S
Sbjct: 123 VALNNDNINTIISRNDVVFVNFYADWCRFSQILAPRLMKPPEKYLKSS 266

 Score = 23.9 bits (50), Expect(2) = 7.9,   Method: Compositional matrix adjust.
 Identities = 16/58 (27%), Positives = 27/58 (46%), Gaps = 1/58 (1%)
 Frame = +2

Query: 574 LVIAKMDATANDITNDQYKVEGFPTIYFAPSGDKKNPIKFE-GGNRDLEHLSKFIDEH 630
           ++ AK+D         QY++  +PT+    +G     +K E  G R  + L+ FI E 
Sbjct: 281 VLFAKVDCDKEVTIASQYRISKYPTLKLFRNGQM---VKKEFRGQRSADALAAFIREE 445

 Score = 23.1 bits (48), Expect(2) = 7.9,   Method: Compositional matrix adjust.
 Identities = 8/18 (44%), Positives = 10/18 (55%)
 Frame = +3

Query: 542 VLIEFYAPWCGHCKQLEP 559
           V + FYA WC   + L P
Sbjct: 174 VFVNFYADWCRFSQILAP 227
>36159
          Length = 369

 Score = 55.5 bits (132), Expect = 8e-08,   Method: Composition-based stats.
 Identities = 22/34 (64%), Positives = 28/34 (82%)
 Frame = -1

Query: 548 APWCGHCKQLEPIYTSLGKKYKGQKDLVIAKMDA 581
           APWCGHCKQL PI+  LG+K++   D+VIAKMD+
Sbjct: 102 APWCGHCKQLVPIWDELGEKFQDSDDVVIAKMDS 1

 Score = 42.0 bits (97), Expect = 8e-04,   Method: Composition-based stats.
 Identities = 15/35 (42%), Positives = 25/35 (71%)
 Frame = -1

Query: 84  APWCGHCKQFAPEYEKIASTLKDNDPPIAVAKIDA 118
           APWCGHCKQ  P ++++    +D+D  + +AK+D+
Sbjct: 102 APWCGHCKQLVPIWDELGEKFQDSD-DVVIAKMDS 1

 Score = 35.4 bits (80), Expect = 0.071,   Method: Composition-based stats.
 Identities = 14/35 (40%), Positives = 25/35 (71%)
 Frame = -1

Query: 199 APWCGHCKKLAPEYEKAAKELSKRSPPIPLAKVDA 233
           APWCGHCK+L P +++  ++  + S  + +AK+D+
Sbjct: 102 APWCGHCKQLVPIWDELGEKF-QDSDDVVIAKMDS 1
>15159
          Length = 1945

 Score = 51.2 bits (121), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 23/73 (31%), Positives = 40/73 (54%)
 Frame = +3

Query: 179 TKDNFDDVVNNADIILVEFYAPWCGHCKKLAPEYEKAAKELSKRSPPIPLAKVDATEQTD 238
           + D+F+  +    +++V+F+A WCG CK +AP+  K ++E  +    + +  VD  E  D
Sbjct: 96  SADDFEKAIQGGQLVVVDFHATWCGPCKVIAPKLAKWSEE-DRFKETVKIISVDVDELED 272

Query: 239 LAKRFDVSGYPTL 251
           LA    +S  PT 
Sbjct: 273 LAGEQGISAMPTF 311

 Score = 37.0 bits (84), Expect = 0.027,   Method: Compositional matrix adjust.
 Identities = 19/74 (25%), Positives = 36/74 (48%)
 Frame = +3

Query: 67  NFDNFVADKDTVLLEFYAPWCGHCKQFAPEYEKIASTLKDNDPPIAVAKIDATSASMLAS 126
           +F+  +     V+++F+A WCG CK  AP+  K +   +  +  + +  +D      LA 
Sbjct: 105 DFEKAIQGGQLVVVDFHATWCGPCKVIAPKLAKWSEEDRFKE-TVKIISVDVDELEDLAG 281

Query: 127 KFDVSGYPTIKILK 140
           +  +S  PT   L+
Sbjct: 282 EQGISAMPTFFFLE 323

 Score = 34.7 bits (78), Expect = 0.11,   Method: Compositional matrix adjust.
 Identities = 14/60 (23%), Positives = 30/60 (50%)
 Frame = +3

Query: 542 VLIEFYAPWCGHCKQLEPIYTSLGKKYKGQKDLVIAKMDATANDITNDQYKVEGFPTIYF 601
           V+++F+A WCG CK + P      ++ + ++ + I  +D    +    +  +   PT +F
Sbjct: 138 VVVDFHATWCGPCKVIAPKLAKWSEEDRFKETVKIISVDVDELEDLAGEQGISAMPTFFF 317
>04779
          Length = 910

 Score = 44.7 bits (104), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 25/90 (27%), Positives = 44/90 (48%), Gaps = 5/90 (5%)
 Frame = +1

Query: 111 IAVAKIDATSASMLASKFDVSGYPTIKIL-----KKGQAVDYDGSRTQEEIVAKVREVSQ 165
           +    +DAT+    A++++V GYPTIK       +   A +Y+G RT  +I+A   +   
Sbjct: 16  VKFGALDATAHQNKAAEYNVRGYPTIKFFPANSNRASDAQEYNGGRTASDIIAWASDKHT 195

Query: 166 PDWTPPPEVTLSLTKDNFDDVVNNADIILV 195
            +  PPPE+    ++  FD       + +V
Sbjct: 196 EN-VPPPELIEITSESTFDSACEGKPLCVV 282

 Score = 33.1 bits (74), Expect = 0.32,   Method: Compositional matrix adjust.
 Identities = 23/92 (25%), Positives = 39/92 (42%), Gaps = 9/92 (9%)
 Frame = +1

Query: 226 IPLAKVDATEQTDLAKRFDVSGYPTLKIF-----RKGRPFDYNGPREKYGIV----DYMI 276
           +    +DAT   + A  ++V GYPT+K F     R     +YNG R    I+    D   
Sbjct: 16  VKFGALDATAHQNKAAEYNVRGYPTIKFFPANSNRASDAQEYNGGRTASDIIAWASDKHT 195

Query: 277 EQSGPPSKEILTLKQVQEFLKDGDDVVIIGLF 308
           E   PP    +T +   +   +G  + ++ + 
Sbjct: 196 ENVPPPELIEITSESTFDSACEGKPLCVVSVL 291

 Score = 30.0 bits (66), Expect = 3.3,   Method: Compositional matrix adjust.
 Identities = 16/54 (29%), Positives = 29/54 (53%), Gaps = 2/54 (3%)
 Frame = +1

Query: 579 MDATANDITNDQYKVEGFPTIYFAPSGDKK--NPIKFEGGNRDLEHLSKFIDEH 630
           +DATA+     +Y V G+PTI F P+   +  +  ++ GG    + ++   D+H
Sbjct: 31  LDATAHQNKAAEYNVRGYPTIKFFPANSNRASDAQEYNGGRTASDIIAWASDKH 192
>09979
          Length = 1785

 Score = 30.0 bits (66), Expect = 2.8,   Method: Compositional matrix adjust.
 Identities = 18/50 (36%), Positives = 23/50 (46%), Gaps = 2/50 (4%)
 Frame = +1

Query: 156 IVAKVREVSQPDWTPPPEVTLS-LTKDNFDDVVNN-ADIILVEFYAPWCG 203
           +VA +R VSQ    P P  T S L K     ++   A + LV    PWC 
Sbjct: 397 VVASIRTVSQTXSVPAPATTKSVLAKQTTQQMITKCAKVELVPCSVPWCS 546
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|40254215|ref|NP_766058.2| WD repeat domain 35 [Mus
musculus]
         (1181 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

28703                                                                 206   8e-87
16237                                                                 248   1e-81
28289                                                                 204   2e-52
20391                                                                  45   1e-04
19498                                                                  42   0.002
01249                                                                  38   0.028
10313                                                                  34   0.38 
02147                                                                  33   0.84 
12140                                                                  31   3.4  
00992                                                                  30   4.1  
01805                                                                  30   4.9  
01768                                                                  30   5.9  
04358                                                                  30   6.1  
>28703
          Length = 659

 Score =  206 bits (524), Expect(3) = 8e-87,   Method: Compositional matrix adjust.
 Identities = 89/115 (77%), Positives = 105/115 (91%)
 Frame = +1

Query: 261 WNHIGSVLAVAGSQKVVTQDKDINIVQFYTPFGEHLGTLKVPGKQMCSLSWEGGGLKIAL 320
           WNH G++LAVAGSQ  + QDK++N+VQFYTP GEHL TLKVPGK M S SWEGG L+I+L
Sbjct: 274 WNHTGAILAVAGSQHALGQDKEVNVVQFYTPLGEHLRTLKVPGKNMYSCSWEGGSLRISL 453

Query: 321 AVDSFIYFANIRPDYKWGYCSNTVVYAYTRPDRPEYCVVFWDTKNSEKYVKYVKS 375
           AVDSFIYFANIRPDYKWGYC+NTVVY++T+PDRPE+CV+FWDTKN+EKYVKYVK+
Sbjct: 454 AVDSFIYFANIRPDYKWGYCTNTVVYSFTKPDRPEHCVIFWDTKNNEKYVKYVKT 618

 Score =  132 bits (333), Expect(3) = 8e-87,   Method: Composition-based stats.
 Identities = 53/77 (68%), Positives = 66/77 (85%)
 Frame = +2

Query: 171 LLFGMANGEIHIYDNQGNFIMKMKLNCLVNVTGAISIAGIHWYHGTEGYVEPDCPCLAIC 230
           +LFG+ANGE+H++DN GNFI K+++ CL NVTGAI IAG+ WY+G  GYVEP+CP LA+C
Sbjct: 2   ILFGIANGEVHVFDNTGNFISKLQVFCLTNVTGAIRIAGLEWYNGNFGYVEPNCPSLALC 181

Query: 231 FDNGRCQIMRHENDQNP 247
           FDNGRCQIMR E D+NP
Sbjct: 182 FDNGRCQIMRSEIDENP 232

 Score = 23.1 bits (48), Expect(3) = 8e-87,   Method: Composition-based stats.
 Identities = 9/15 (60%), Positives = 11/15 (73%)
 Frame = +3

Query: 245 QNPVLIDTGMYVVGI 259
           + P+LIDTGM V  I
Sbjct: 225 RTPILIDTGMQVAQI 269
>16237
          Length = 740

 Score =  248 bits (632), Expect(2) = 1e-81,   Method: Compositional matrix adjust.
 Identities = 121/193 (62%), Positives = 147/193 (76%), Gaps = 1/193 (0%)
 Frame = -3

Query: 458 KKLTALEINQITRSRKEGRERIYHXXXXXX-XXXXXXXXYSKAIQGTRDPICAITASDKT 516
           KKL  LE+ +    RK G E+++H               +SKA  GT DPIC + ASDK 
Sbjct: 567 KKLATLEMAR----RKGGSEKLFHIDDIPSGTTTQDEVDFSKAYAGTEDPICCMCASDKA 400

Query: 517 LIVGRESGVIQRYSFPNVALIQKYSLDCRACQLSLNCNSSRLAIIDIAGVLTFFDLDTRV 576
           L+VGRESG++ RY+ P++AL  KY+L CR  QLSLNC+SSRLAIIDIAGVLTFFDLDTRV
Sbjct: 399 LVVGRESGLLVRYAMPSLALTHKYNLSCRPHQLSLNCSSSRLAIIDIAGVLTFFDLDTRV 220

Query: 577 TDSTGQQVVGELLKLERKDVWDMKWAKDNPDLFAMMEKTRMYVFRNLDPEEPIQTSGHIC 636
           TD  G++VVGE L  ERKDVWDMKWA+DN +LFAMMEKTRMY+FR+L+PEEPI +SG+IC
Sbjct: 219 TDPDGREVVGEHLNFERKDVWDMKWAEDNSELFAMMEKTRMYIFRSLEPEEPILSSGYIC 40

Query: 637 NFEDLEIKSVLLD 649
            F DL+IK+VLLD
Sbjct: 39  QFSDLQIKAVLLD 1

 Score = 75.5 bits (184), Expect(2) = 1e-81,   Method: Compositional matrix adjust.
 Identities = 37/67 (55%), Positives = 46/67 (68%)
 Frame = -2

Query: 389 ATKADENHPQEENEMETFGATFVLVLCNSIGTPLDPKYIDLVPLFVAMTKTHVIAASKEA 448
            TKADE   Q           +VLVLCNSIGTPLD KYI++ P+++ MTKTH+I A KEA
Sbjct: 739 GTKADEVVGQ-----------YVLVLCNSIGTPLDSKYIEMDPVYLTMTKTHIIYACKEA 593

Query: 449 FYTWQYR 455
           FY WQ++
Sbjct: 592 FYCWQFK 572
>28289
          Length = 349

 Score =  204 bits (518), Expect = 2e-52,   Method: Compositional matrix adjust.
 Identities = 98/116 (84%), Positives = 106/116 (91%), Gaps = 1/116 (0%)
 Frame = -1

Query: 33  GEDGLLKVLRLETQTD-DSKLRGLAAPSNLSMNQNLEGHSGAVQVVTWNEQYQKLTTSDQ 91
           GE+GLLKVL+LE Q   D+K++GLAAPSNLSMNQ+LEGHSGAVQVV WNE +QKLTTSDQ
Sbjct: 349 GEEGLLKVLKLEMQAGKDAKVKGLAAPSNLSMNQSLEGHSGAVQVVAWNEHHQKLTTSDQ 170

Query: 92  NGLIIVWMLYKGSWYEEMINNRNKSVVRSMSWNADGQKICIVYEDGAVIVGSVDGN 147
            GLIIVWMLYKGSWYEEMINNRNKSVVR M W ADGQKICIVYEDGAVIVGS+DGN
Sbjct: 169 YGLIIVWMLYKGSWYEEMINNRNKSVVRGMKWTADGQKICIVYEDGAVIVGSLDGN 2
>20391
          Length = 582

 Score = 45.4 bits (106), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 34/136 (25%), Positives = 63/136 (46%), Gaps = 1/136 (0%)
 Frame = -1

Query: 816 WQNAVQYYVKGRNQERLAECYYMLEDYEGLETLANSLPENHKLLPEIAQMFVRVGMCEQA 875
           W+N  +  VK R  +  + C   +    G + L  +L E  +L   +A + +++G+ E  
Sbjct: 414 WENMAKMCVKSRRLDVASVCLGNMGHARGAKALREALKEP-ELDARVAVLAIQLGLHEDG 238

Query: 876 VSAFLKCNQPKAAVDTCVHLNQWNKAVELAKSHSMKEIGSLLARYASHLLEKNKTLDAIE 935
                 C +     +   +  QWNKA+E A+ +    + S    YA HL E+  T  AI 
Sbjct: 237 ERLLRNCKRYDLLNEFYQNSGQWNKALETAEMYDRIHLRSTYYNYAHHLEERGDTNGAIP 58

Query: 936 LYRKA-SYFFDAAKLM 950
            Y K+ ++ F+  +++
Sbjct: 57  NYEKSETHRFEVPRML 10
>19498
          Length = 903

 Score = 41.6 bits (96), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 29/118 (24%), Positives = 59/118 (50%), Gaps = 6/118 (5%)
 Frame = -1

Query: 17  LKCISWNKDQGFIACGGEDGLLKVLRLETQTDDSKLRGLAAPSNLSMNQN------LEGH 70
           + C+ W+++  F+A GG+D L+ + ++       K  G    SN+++ ++      L GH
Sbjct: 777 VNCVRWSENGKFLASGGDDKLIMIWQISRGFGSGKSFG----SNVTILEHWRSVATLRGH 610

Query: 71  SGAVQVVTWNEQYQKLTTSDQNGLIIVWMLYKGSWYEEMINNRNKSVVRSMSWNADGQ 128
           +G V  + W+ Q   L +   +  I+VW   K S    +I   +  +V+ ++W+  G+
Sbjct: 609 AGDVLDLAWSPQDLWLASCSVDNTIVVWNALKFSEQVAVIRG-HAGMVKGVTWDPVGR 439

 Score = 29.6 bits (65), Expect = 6.6,   Method: Compositional matrix adjust.
 Identities = 11/37 (29%), Positives = 21/37 (56%)
 Frame = -1

Query: 67  LEGHSGAVQVVTWNEQYQKLTTSDQNGLIIVWMLYKG 103
           ++ H G V  V W+E  + L +   + LI++W + +G
Sbjct: 798 MDSHLGCVNCVRWSENGKFLASGGDDKLIMIWQISRG 688
>01249
          Length = 1743

 Score = 37.7 bits (86), Expect = 0.028,   Method: Compositional matrix adjust.
 Identities = 22/87 (25%), Positives = 46/87 (52%)
 Frame = -1

Query: 17   LKCISWNKDQGFIACGGEDGLLKVLRLETQTDDSKLRGLAAPSNLSMNQNLEGHSGAVQV 76
            + C+  +K + F+  G ++G +    L  Q   S++  ++  +  +  + L+GHS AV  
Sbjct: 1074 VGCLIMDKQEHFLLAGLDNGDILCSPLFGQISQSEVF-VSKHTTKAGERVLQGHSDAVTC 898

Query: 77   VTWNEQYQKLTTSDQNGLIIVWMLYKG 103
            + ++   Q+L +  QNG +I+W +  G
Sbjct: 897  LAFSSDGQRLASGSQNGKVIIWNMESG 817
>10313
          Length = 689

 Score = 33.9 bits (76), Expect = 0.38,   Method: Compositional matrix adjust.
 Identities = 20/76 (26%), Positives = 40/76 (52%)
 Frame = +3

Query: 711 DLYTAQQAFVRCKDYQGIKFVKLLGNLQSESMKQAEVIAYFGRFEDAERMYQDMDRRDLA 770
           DL TA+ A+   K+ + ++F+  + ++  +  + AE+    G + DAE +         A
Sbjct: 9   DLNTAEVAYAAIKEVEKVQFISNIKDIPVKEARNAEMALLCGNYNDAEAILLQAGLIFRA 188

Query: 771 IGLRMKLGDWFRVLQL 786
           + L ++L +W R L+L
Sbjct: 189 VLLNIQLYNWDRALEL 236
>02147
          Length = 1547

 Score = 32.7 bits (73), Expect = 0.84,   Method: Compositional matrix adjust.
 Identities = 19/65 (29%), Positives = 31/65 (47%)
 Frame = +2

Query: 66  NLEGHSGAVQVVTWNEQYQKLTTSDQNGLIIVWMLYKGSWYEEMINNRNKSVVRSMSWNA 125
             EGH GAV   T N +  +  T   +    +W   KG   EE+    +K +V+S+ ++ 
Sbjct: 158 TFEGHKGAVWGATLNREATRAATGAADFSAKIWDAEKG---EELQTFSHKHIVKSVDFSH 328

Query: 126 DGQKI 130
           DG  +
Sbjct: 329 DGTAL 343
>12140
          Length = 727

 Score = 30.8 bits (68), Expect = 3.4,   Method: Composition-based stats.
 Identities = 33/135 (24%), Positives = 54/135 (40%), Gaps = 6/135 (4%)
 Frame = +2

Query: 32  GGEDGLLKVLRLETQTDDSKLRGLAAPSNLSMNQNLEGHSGAVQVVTWNEQY----QKLT 87
           GG D L+K+ R E +T                +Q LEGHS  V+ V W          + 
Sbjct: 278 GGCDNLVKIWR-EDET------------GWVEDQKLEGHSDWVRDVAWAPSIGLPRNVIA 418

Query: 88  TSDQNGLIIVWMLYKGS--WYEEMINNRNKSVVRSMSWNADGQKICIVYEDGAVIVGSVD 145
           +  Q+  +I+W     S  W   ++ N+   VV  +SW+  G  + +   D  V      
Sbjct: 419 SCSQDCRVIIWTNDGSSNQWTSRIL-NKFSDVVWHVSWSVTGNILAVSGGDNKVT----- 580

Query: 146 GNRIWGKDLKGIQLC 160
              +W + ++G   C
Sbjct: 581 ---LWKESVEGQWTC 616
>00992
          Length = 1754

 Score = 30.4 bits (67), Expect = 4.1,   Method: Compositional matrix adjust.
 Identities = 16/45 (35%), Positives = 21/45 (46%)
 Frame = +2

Query: 1097 LSAEQKQQYEDLALEIFTKHTPKDNRKSELNSLLEGGEGKLPTCI 1141
            L  ++    ED+  EIF    P D  K  LN L+  G+G    CI
Sbjct: 224  LRGQEPVSLEDIKDEIFDMVKPADPLKLTLNDLISCGKGDTVACI 358
>01805
          Length = 2124

 Score = 30.4 bits (67), Expect = 4.9,   Method: Compositional matrix adjust.
 Identities = 22/107 (20%), Positives = 51/107 (47%), Gaps = 1/107 (0%)
 Frame = -1

Query: 65  QNLEGHSGAVQVVTWNEQYQK-LTTSDQNGLIIVWMLYKGSWYEEMINNRNKSVVRSMSW 123
           +++ GH+ AV  ++WN   +  L ++  +  + +W L +G     M   ++   V+  +W
Sbjct: 594 ESVTGHTQAVLDLSWNRNARHVLASASADTTVALWDLSEGK--MAMNFTQHSREVQCCNW 421

Query: 124 NADGQKICIVYEDGAVIVGSVDGNRIWGKDLKGIQLCHVTWSADSKI 170
           +          E+  ++ GS D N +   D +  + CH +W+ + ++
Sbjct: 420 HP--------QEEQTLLTGSFD-NTVKVVDCRSAETCHKSWTVEGEV 307
>01768
          Length = 1424

 Score = 30.0 bits (66), Expect = 5.9,   Method: Compositional matrix adjust.
 Identities = 34/137 (24%), Positives = 58/137 (42%), Gaps = 7/137 (5%)
 Frame = +3

Query: 20  ISWNKDQG--FIACGGEDGLLKVLRL-ETQTDDSKLRGLAAPSNLSMNQNLEGHSGAVQV 76
           + W+ ++G  F +C  +    + LR+  TQ   SK   L  P         E HS  + V
Sbjct: 855 VQWSPNEGNVFASCSVD----RTLRIWNTQQKPSKANVLTVP---------EAHSRDINV 995

Query: 77  VTWNE-QYQKLTTSDQNGLIIVWMLYKGSWYEEMINNRNKSVVRSMSWNADGQKICIVY- 134
           + WN  +   L +   +G+I +W L        M   RNK V    S+    Q +  +  
Sbjct: 996 INWNPIEKHLLASGGDDGIIKIWDL-------RMF--RNKPVSAQASFKLHSQPVTSLEW 1148

Query: 135 --EDGAVIVGSVDGNRI 149
             +D +V+  S + ++I
Sbjct: 1149NPQDSSVLAASGEDDQI 1199
>04358
          Length = 2430

 Score = 30.0 bits (66), Expect = 6.1,   Method: Composition-based stats.
 Identities = 20/84 (23%), Positives = 36/84 (42%), Gaps = 2/84 (2%)
 Frame = +1

Query: 17   LKCISWNKDQG--FIACGGEDGLLKVLRLETQTDDSKLRGLAAPSNLSMNQNLEGHSGAV 74
            + CI  N+      +  G   G L VL L    +   +R L+            GH+  V
Sbjct: 2011 VDCIPANQSTSPPCLVAGTHTGDLHVLDLSDLEEVKVVRSLSG-----------GHTDTV 2157

Query: 75   QVVTWNEQYQKLTTSDQNGLIIVW 98
            + + W++Q Q L T  ++ ++ +W
Sbjct: 2158 RCLHWDKQTQTLVTGGEDSMLCLW 2229
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|27532946|ref|NP_034441.1| guanine nucleotide binding
protein, alpha z subunit [Mus musculus]
         (355 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

11965                                                                 316   1e-86
13527                                                                 182   2e-46
29196                                                                 122   2e-28
20516                                                                 102   2e-22
34094                                                                  54   1e-07
09827                                                                  43   2e-04
18949                                                                  42   4e-04
08153                                                                  42   4e-04
10862                                                                  42   5e-04
11378                                                                  36   0.027
18208                                                                  35   0.062
>11965
          Length = 3256

 Score =  316 bits (809), Expect = 1e-86,   Method: Compositional matrix adjust.
 Identities = 150/221 (67%), Positives = 176/221 (79%)
 Frame = +1

Query: 134 DPGAQACFGRSSEYHLEDNAAYYLNDLERIAAPDYIPTVEDILRSRDMTTGIVENKFTFK 193
           D G Q CF RS+EY L D+A Y+L+DL+R+   DY+PT +DILR+R  TTGIVE  F+FK
Sbjct: 1   DSGVQDCFSRSNEYQLNDSAKYFLDDLDRLGTKDYMPTEQDILRTRVKTTGIVEVHFSFK 180

Query: 194 ELTFKMVDVGGQRSERKKWIHCFEGVTAIIFCVELSGYDLKLYEDNQTSRMAESLRLFDS 253
            L FK+ DVGGQRSERKKWIHCFE VTAIIFCV +S YD  L+ED  T+RM ESL+LFDS
Sbjct: 181 NLNFKLFDVGGQRSERKKWIHCFEDVTAIIFCVAMSEYDQVLHEDETTNRMQESLKLFDS 360

Query: 254 ICNNNWFINTSLILFLNKKDLLAEKIRRIPLSVCFPEYKGQNTYEEAAVYIQRQFEDLNR 313
           ICNN WF +TS+ILFLNKKDL  EKI++ PL+VCFPEY G+ TYEE A YIQ QFE  N+
Sbjct: 361 ICNNKWFTDTSIILFLNKKDLFEEKIKKSPLTVCFPEYTGKQTYEEVAAYIQAQFEAKNK 540

Query: 314 NKETKEIYSHFTCATDTSNIQFVFDAVTDVIIQNNLKYIGL 354
           + + KEIY H TCATDT+NIQFVFDAVTDVII NNL+  GL
Sbjct: 541 SSQ-KEIYCHQTCATDTNNIQFVFDAVTDVIIANNLRGCGL 660
>13527
          Length = 1091

 Score =  182 bits (461), Expect = 2e-46,   Method: Compositional matrix adjust.
 Identities = 91/200 (45%), Positives = 116/200 (58%)
 Frame = -2

Query: 1    MGCXXXXXXXXXXXXXXXXXXXXXSESQRQRREIKLLLLGTSNSGKSTIVKQMKIIHSGG 60
            MGC                      +  +  ++IKLLLLG   SGKSTIVKQMKIIH GG
Sbjct: 1042 MGCTLSAEERAAMERSKAIEKNLKEDGMQAAKDIKLLLLGAGESGKSTIVKQMKIIHEGG 863

Query: 61   FNLDACKEYKPLIIYNAIDSLTRIIRALAALKIDFHNPDRAYDAVQLFALTGPAESKGEI 120
            F  +  K+Y+P++  N I SL  IIRA+  L I F + +R  DA  +  +    E     
Sbjct: 862  FTSEDNKQYRPVVFSNTIQSLVAIIRAMGTLSIPFGDNERESDAKMVLDVIARMEDTEPF 683

Query: 121  TPELLGVMRRLWADPGAQACFGRSSEYHLEDNAAYYLNDLERIAAPDYIPTVEDILRSRD 180
            + ELL  M RLW D G Q CF RS+EY L D+A Y+L+DL+R+   DY+PT +DILR+R 
Sbjct: 682  SEELLAAMERLWMDSGVQDCFSRSNEYQLNDSAKYFLDDLDRLGTKDYMPTEQDILRTRV 503

Query: 181  MTTGIVENKFTFKELTFKMV 200
             TTGIVE  F+FK L FK V
Sbjct: 502  KTTGIVEVHFSFKNLNFKYV 443
>29196
          Length = 431

 Score =  122 bits (307), Expect = 2e-28,   Method: Compositional matrix adjust.
 Identities = 56/76 (73%), Positives = 63/76 (82%)
 Frame = -2

Query: 193 KELTFKMVDVGGQRSERKKWIHCFEGVTAIIFCVELSGYDLKLYEDNQTSRMAESLRLFD 252
           K L FK+ DVGGQRSERKKWIHCFE VTAIIFCV +S YD  L+ED  T+RM ESL+LFD
Sbjct: 229 KNLNFKLFDVGGQRSERKKWIHCFEDVTAIIFCVAMSEYDQVLHEDETTNRMQESLKLFD 50

Query: 253 SICNNNWFINTSLILF 268
           SICNN WF +TS+ILF
Sbjct: 49  SICNNKWFTDTSIILF 2

 Score = 74.3 bits (181), Expect = 6e-14,   Method: Compositional matrix adjust.
 Identities = 35/63 (55%), Positives = 47/63 (74%)
 Frame = -1

Query: 141 FGRSSEYHLEDNAAYYLNDLERIAAPDYIPTVEDILRSRDMTTGIVENKFTFKELTFKMV 200
           F RS+EY L D+A Y+L+DL+R+ A DY PT +DILR+R  TTGIVE  F+FK+  F++V
Sbjct: 386 FSRSNEYQLNDSAKYFLDDLDRLGAKDYQPTEQDILRTRVKTTGIVEVHFSFKKSEFQIV 207

Query: 201 DVG 203
             G
Sbjct: 206 *CG 198
>20516
          Length = 534

 Score =  102 bits (255), Expect = 2e-22,   Method: Compositional matrix adjust.
 Identities = 62/163 (38%), Positives = 89/163 (54%), Gaps = 1/163 (0%)
 Frame = +2

Query: 191 TFKELTFKMVDV-GGQRSERKKWIHCFEGVTAIIFCVELSGYDLKLYEDNQTSRMAESLR 249
           TF+ + F + +V GGQRS+R+KW  CF G+T+I+F    S +D  L ED +T+R+ ES  
Sbjct: 41  TFRNIFFLVGEVTGGQRSQRQKWYQCFVGITSILFLAASSEFDQVLMEDRKTNRLQESCD 220

Query: 250 LFDSICNNNWFINTSLILFLNKKDLLAEKIRRIPLSVCFPEYKGQNTYEEAAVYIQRQFE 309
           +F++I NN  F   S+ILFLNK DLL +K     L   F  + G +     +  I     
Sbjct: 221 IFETIINNKSFSGVSIILFLNKMDLLQDKN*ACQLRRLFSRFSG*SQGH*CSQSI*ASAV 400

Query: 310 DLNRNKETKEIYSHFTCATDTSNIQFVFDAVTDVIIQNNLKYI 352
                   +    HFT A DT NI+ VF  V D I+ +NL+ +
Sbjct: 401 *FAPT*SKQTFVHHFTTAIDTENIKHVFQDVKDTILHDNLRSL 529
>34094
          Length = 452

 Score = 53.5 bits (127), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 24/55 (43%), Positives = 37/55 (67%)
 Frame = +1

Query: 54  KIIHSGGFNLDACKEYKPLIIYNAIDSLTRIIRALAALKIDFHNPDRAYDAVQLF 108
           +IIH  G++ + C +YKP++  NAI S+  I+RA+  L ++F +PDR   AV LF
Sbjct: 103 RIIHEKGYSQEECLQYKPVVYSNAIQSMIAIVRAMNLLSVEFGHPDR---AVSLF 258
>09827
          Length = 1201

 Score = 42.7 bits (99), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 24/83 (28%), Positives = 39/83 (46%)
 Frame = -3

Query: 192 FKELTFKMVDVGGQRSERKKWIHCFEGVTAIIFCVELSGYDLKLYEDNQTSRMAESLRLF 251
           +K ++F + DVGGQ   R  W H F+    +IF V          + N   R+ E+    
Sbjct: 992 YKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVV----------DSNDKERVQEAREEL 843

Query: 252 DSICNNNWFINTSLILFLNKKDL 274
             + N +   +  L++F NK+DL
Sbjct: 842 TRMLNEDELRDAVLLVFANKQDL 774
>18949
          Length = 414

 Score = 42.0 bits (97), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 24/97 (24%), Positives = 44/97 (45%), Gaps = 1/97 (1%)
 Frame = +3

Query: 178 SRDMTTGI-VENKFTFKELTFKMVDVGGQRSERKKWIHCFEGVTAIIFCVELSGYDLKLY 236
           S+   TG+    + +   +TF   D+GG R  R+ W   F  V  I+F V++        
Sbjct: 3   SQHRPTGLPTSEELSMGGMTFTTFDLGGHRQARRVWKDYFPAVDGIVFIVDV-------- 158

Query: 237 EDNQTSRMAESLRLFDSICNNNWFINTSLILFLNKKD 273
             + T R+ E+    DS+  ++   +  +++  NK D
Sbjct: 159 --HDTERITEAKAELDSLLRDDQIADIPVLVLGNKMD 263
>08153
          Length = 1703

 Score = 42.0 bits (97), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 30/120 (25%), Positives = 50/120 (41%), Gaps = 1/120 (0%)
 Frame = +1

Query: 182 TTGIVENKFTFKELTFKMVDVGGQRSERKKWIHCFEGVTAIIFCVELSGYDLKLYEDNQT 241
           T G       +K ++F + DVGGQ   R  W H F+    +IF V          + N  
Sbjct: 175 TIGFNVETVEYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVV----------DSNDR 324

Query: 242 SRMAESLRLFDSICNNNWFINTSLILFLNKKDLL-AEKIRRIPLSVCFPEYKGQNTYEEA 300
            R+ E+      + N +   +  +++F NK+DL  A     +   +     KG+  Y +A
Sbjct: 325 ERINEAKEELARMLNEDDLRDAIILVFANKQDLPNAYSASEVTAHLGLANLKGRKWYMQA 504
>10862
          Length = 2896

 Score = 41.6 bits (96), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 24/83 (28%), Positives = 39/83 (46%)
 Frame = -3

Query: 192  FKELTFKMVDVGGQRSERKKWIHCFEGVTAIIFCVELSGYDLKLYEDNQTSRMAESLRLF 251
             +E  F + DVGGQ   R  W H + G   +IF V+ +  D          R+ E+ +  
Sbjct: 2495 LQECQFNVWDVGGQDKIRPLWRHYYTGTQGLIFVVDCADRD----------RIDEARQEL 2346

Query: 252  DSICNNNWFINTSLILFLNKKDL 274
              I N+    +  +++F NK+DL
Sbjct: 2345 HRIINDREMRDAIILIFANKQDL 2277
>11378
          Length = 1688

 Score = 35.8 bits (81), Expect = 0.027,   Method: Compositional matrix adjust.
 Identities = 20/79 (25%), Positives = 34/79 (43%)
 Frame = +3

Query: 195 LTFKMVDVGGQRSERKKWIHCFEGVTAIIFCVELSGYDLKLYEDNQTSRMAESLRLFDSI 254
           + F   D+GG R  R+ W   F  V  I+F V++          +   R+ E+    DS+
Sbjct: 453 MRFTTFDLGGHRQARRVWKDYFPAVDGIVFLVDV----------HDRERLVEAKAELDSL 602

Query: 255 CNNNWFINTSLILFLNKKD 273
             +    N  +++  NK D
Sbjct: 603 MTDEQVANAPILVLGNKID 659
>18208
          Length = 458

 Score = 34.7 bits (78), Expect = 0.062,   Method: Compositional matrix adjust.
 Identities = 16/42 (38%), Positives = 28/42 (66%), Gaps = 6/42 (14%)
 Frame = -1

Query: 32  REIKLLLLGTSNSGKSTIVKQM------KIIHSGGFNLDACK 67
           RE+++LLLG  N+GK+T++KQ+       I  + GFN+ + +
Sbjct: 305 RELRILLLGLDNAGKTTLLKQLASEDPSHITPTQGFNIKSVQ 180

 Score = 29.6 bits (65), Expect = 2.1,   Method: Compositional matrix adjust.
 Identities = 12/37 (32%), Positives = 19/37 (51%)
 Frame = -1

Query: 193 KELTFKMVDVGGQRSERKKWIHCFEGVTAIIFCVELS 229
           K     + D+GGQR  R  W + FE    +I+ ++ S
Sbjct: 176 KGFKLNVWDIGGQRRIRPYWKNYFENTDLLIYVIDSS 66
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6755126|ref|NP_035265.1| CCR4-NOT transcription
complex, subunit 7 [Mus musculus]
         (285 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

04671                                                                 315   1e-86
09380                                                                  29   2.8  
>04671
          Length = 2480

 Score =  315 bits (807), Expect = 1e-86,   Method: Compositional matrix adjust.
 Identities = 156/213 (73%), Positives = 182/213 (85%)
 Frame = +2

Query: 46  VVARPIGEFRSNADYQYQLLRCNVDLLKIIQLGLTFMNEQGEYPPGTSTWQFNFKFNLTE 105
           VVARPIGEFRS +DYQYQLLRCNV+LLKIIQ+G++F +++G      STWQFNFKFNLTE
Sbjct: 2   VVARPIGEFRSTSDYQYQLLRCNVNLLKIIQIGISFFDDKGNRASPVSTWQFNFKFNLTE 181

Query: 106 DMYAQDSIELLTTSGIQFKKHEEEGIETQYFAELLMTSGVVLCEGVKWLSFHSGYDFGYL 165
           DMYAQ+SIELL  SGIQF++HE +GI    FAELL++SGVVL + + WLSFHSGYDFGY+
Sbjct: 182 DMYAQESIELLRRSGIQFERHETDGIHPDDFAELLISSGVVLMDDISWLSFHSGYDFGYM 361

Query: 166 IKILTNSNLPEEELDFFEILRLFFPVIYDVKYLMKSCKNLKGGLQEVAEQLELERIGPQH 225
           ++ILT  NL  EE  FF +L+LFF  IYDVKYLMKSCKNLKGGLQEVA+QLE++RIGPQH
Sbjct: 362 LRILTGENLACEESQFFVLLKLFFLNIYDVKYLMKSCKNLKGGLQEVADQLEIKRIGPQH 541

Query: 226 QAGSDSLLTGMAFFKMREMFFEDHIDDAKYCGH 258
           QAGSDSLLTG AFFKMRE+FFED +D  KYCGH
Sbjct: 542 QAGSDSLLTGDAFFKMREVFFEDDVDKGKYCGH 640
>09380
          Length = 1342

 Score = 28.9 bits (63), Expect = 2.8,   Method: Compositional matrix adjust.
 Identities = 19/65 (29%), Positives = 28/65 (43%), Gaps = 4/65 (6%)
 Frame = +3

Query: 75  IQLGLTFMN-EQGEYPPGTSTWQFNFKFNLTEDMYAQ---DSIELLTTSGIQFKKHEEEG 130
           IQL L  M      +PPG + W F   FN    ++ Q   D+  LL  +G    ++ +  
Sbjct: 669 IQLSLLLMTWTDRTFPPGKADWNFLSMFNSLL*LHVQPI*DTTILLLATGQIIARYSDSK 848

Query: 131 IETQY 135
              QY
Sbjct: 849 FSGQY 863
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|94373921|ref|XP_985691.1| PREDICTED: similar to
purity of essence CG14472-PA [Mus musculus]
         (5127 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

12842                                                                 320   1e-86
12316                                                                 194   2e-56
29301                                                                 174   3e-52
28265                                                                  60   2e-08
35312                                                                  47   2e-04
>12842
          Length = 1091

 Score =  320 bits (820), Expect = 1e-86,   Method: Compositional matrix adjust.
 Identities = 161/287 (56%), Positives = 210/287 (73%), Gaps = 1/287 (0%)
 Frame = +1

Query: 2145 PAKAKIQDMVAIRHTA-CNEQQRTTMILLCEDGSLRIYMANVENTSYWLQPSLQPSSVIS 2203
            PAKAKIQD+VAIRH A  ++QQRTTMILLCEDGSLRIYMANV+NT+YW+ P LQP S I+
Sbjct: 25   PAKAKIQDVVAIRHLASTSDQQRTTMILLCEDGSLRIYMANVDNTNYWMSPFLQPQSPIA 204

Query: 2204 IMKPVXXXXXXXXXXXXSSQVTFPIDFFEHNQQLTDVEFGGNDLLQVYNAQQIKHRLNST 2263
             +KP+             S V FPIDFFEH QQ +D+EFGGND+LQVYN QQ+KHRLN+T
Sbjct: 205  ALKPLKKKKAVKSGRPVGS-VNFPIDFFEHCQQSSDIEFGGNDVLQVYNVQQVKHRLNTT 381

Query: 2264 GMYVANTKPGGFTIEISNNSSTMVMTGMRIQIGTQAIERAPSYIEIFGRTMQLNLSRSRW 2323
            GMY+A++K  GF +EI N ++  VM G+R+ +G+Q  ++APSY+EIFGRT+ ++++R+RW
Sbjct: 382  GMYIASSKSAGFNLEIQNTNTANVMVGLRVLVGSQTADKAPSYLEIFGRTVPVSVTRARW 561

Query: 2324 FDFPFTREEALQADRKLSLFIGASVDPAGVTMIDAVKIYGKTKEQFGWPDEPPEDFPSAS 2383
             D PFTREE+L AD+K++LF+G+S DPAG+TMID+VK+Y KTKE FGWP+EP E      
Sbjct: 562  LDMPFTREESLTADKKVTLFVGSSADPAGITMIDSVKVYIKTKEAFGWPEEPDEFPEPTL 741

Query: 2384 VSNICPPNLNQSNGTGESDSAAPATTSGTVLERLVVSSLEALESCFA 2430
             + +  P       T ESD+A       T  +RL+ S LE L+  FA
Sbjct: 742  PTKVT-PTPGAVTTTTESDNAPSQPIPMTSADRLLGSGLEVLDGAFA 879
>12316
          Length = 1713

 Score =  194 bits (493), Expect(2) = 2e-56,   Method: Compositional matrix adjust.
 Identities = 96/155 (61%), Positives = 116/155 (74%)
 Frame = +3

Query: 3070 SPPDMSPFFLRQYVKGHAADVFEAYTQLLTEMVLRLPYQIKKIADTSSRIPPPVFDHSWF 3129
            +P DMSPFFLRQYVK HA DVFE Y QLLTEMVLRLPYQ+KKIA++  ++P  VFD SW 
Sbjct: 1029 APLDMSPFFLRQYVKCHATDVFEDYPQLLTEMVLRLPYQLKKIAESGQKMPAAVFDISWN 1208

Query: 3130 YFLSEYLMIQQTPFVRRQVRKLLLFICGSKEKYRQLRDLHTLDSHVRGIKKLLEEQGIFL 3189
              LSEY+M QQTPF++RQVRKLLLFICGSKEKYRQLRD H ++SH+  +K +  + G   
Sbjct: 1209 AVLSEYMMTQQTPFMKRQVRKLLLFICGSKEKYRQLRDEHAMESHLAQVKDIGSQGG--W 1382

Query: 3190 RASVVTASSGSALQYDTLISLMEHLKACAEIAAQR 3224
              +   A     L YDTL++L+EHLK C+EIA  R
Sbjct: 1383 DQTQDLAPHSIVLPYDTLLTLIEHLKVCSEIAMAR 1487

 Score = 47.4 bits (111), Expect(2) = 2e-56,   Method: Composition-based stats.
 Identities = 20/43 (46%), Positives = 28/43 (65%)
 Frame = +2

Query: 3227 NWQKFCIKDDSVLYFLLQVSFLVDEGVSPVLLQLLSCALCGSK 3269
            NWQ +C +    L +++  S ++DEGV+P LL LL  ALCG K
Sbjct: 1493 NWQTYCHQHQDALPYIVCASIVLDEGVAPTLLTLLQVALCGVK 1621
>29301
          Length = 439

 Score =  174 bits (442), Expect(2) = 3e-52,   Method: Compositional matrix adjust.
 Identities = 80/114 (70%), Positives = 92/114 (80%)
 Frame = -3

Query: 3609 PGVCGNCGENVYQCHKCRSINYDEKDPFLCNACGFCKYARFDFMLYAKPCCAVDPIENEE 3668
            P   GNCGENVYQCHKCR+INYDEKDPFLCNACGFCKYA+FD  L  KPCCAVDPIENEE
Sbjct: 347  PASVGNCGENVYQCHKCRAINYDEKDPFLCNACGFCKYAKFDLTLLGKPCCAVDPIENEE 168

Query: 3669 DRKKAVSNINTLLDKADRVYHQLMGHRPQLENLLCKVNEAAPEKPQVLPGQRED 3722
            DRKKA+S IN+LL+KADR Y QL  HRP LE+LL +V E + ++  V   QR++
Sbjct: 167  DRKKAISTINSLLEKADRTYKQLQTHRPILESLLIQVTEHSADRLAV--SQRDE 12

 Score = 52.8 bits (125), Expect(2) = 3e-52,   Method: Compositional matrix adjust.
 Identities = 23/36 (63%), Positives = 26/36 (72%)
 Frame = -2

Query: 3579 MIEFADFYENYQASTETLQCPRCSASVPANPGVCGN 3614
            M+E+AD     +   ETLQCPRCSASVPA PGVCG 
Sbjct: 438  MLEYADSTTTCRPPHETLQCPRCSASVPATPGVCGQ 331
>28265
          Length = 742

 Score = 60.5 bits (145), Expect = 2e-08,   Method: Composition-based stats.
 Identities = 22/61 (36%), Positives = 34/61 (55%)
 Frame = -3

Query: 1659 CNKLCTFTITQKEFMNQHWYHCHTCKMVDGVGVCTVCAKVCHKDHEISYAKYGSFFCDCG 1718
            CNK+ ++T     F    +Y C TC   +   +C  C K CH+ H++ + ++  FFCDCG
Sbjct: 677  CNKISSYT----SFPMHDFYRCKTCHTTERNAICVNCIKTCHQGHDVEFIRHDRFFCDCG 510

Query: 1719 A 1719
            A
Sbjct: 509  A 507
>35312
          Length = 561

 Score = 47.0 bits (110), Expect = 2e-04,   Method: Composition-based stats.
 Identities = 23/64 (35%), Positives = 34/64 (53%), Gaps = 2/64 (3%)
 Frame = -3

Query: 1660 NKLCTFTITQKEFMNQHWYHCHTCKMVDGVGVCTVCAKVCHKDHEISYAKYGS--FFCDC 1717
            ++ CTF+  +     Q  Y C TC+     G+C  C+ +CH+ HE+ Y  Y    F CDC
Sbjct: 391  DQKCTFS--EGYVKRQALYACSTCETTGSAGICLACSYLCHEGHEL-YELYTKRDFRCDC 221

Query: 1718 GAKE 1721
            G K+
Sbjct: 220  GNKK 209
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|27229277|ref|NP_149065.2| threonyl-tRNA synthetase
[Mus musculus]
         (722 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

07414                                                                 316   2e-86
19083                                                                 241   8e-64
12449                                                                  60   3e-09
06461                                                                  33   0.34 
28061                                                                  30   4.9  
22318                                                                  29   6.5  
19547                                                                  29   7.7  
24754                                                                  28   9.4  
>07414
          Length = 787

 Score =  316 bits (810), Expect = 2e-86,   Method: Compositional matrix adjust.
 Identities = 150/219 (68%), Positives = 175/219 (79%)
 Frame = -2

Query: 504 FLGDIEIWNQAEKQLENSLNEFGEKWELNPGDGAFYGPKIDIQIKDAIGRYHQCATIQLD 563
           FLG+I +W+ AE+QL   L E G K+ELNPGDGAFYGPKIDI IKDA+ R HQCATIQLD
Sbjct: 783 FLGEISVWDSAEQQLSEVLEESGLKFELNPGDGAFYGPKIDITIKDALRRSHQCATIQLD 604

Query: 564 FQLPIRFNLTYVSHDGDDKKRPVIVHRAILGSVERMIAILTENYGGKWPFWLSPRQVMVV 623
           FQLP RF LTY++  G+ + RPVIVHRA+LGSVERM+AIL EN+GGKWPFWLSPRQ +VV
Sbjct: 603 FQLPERFGLTYINDHGE-RLRPVIVHRAVLGSVERMMAILCENFGGKWPFWLSPRQSIVV 427

Query: 624 PVGPTCDEYAQKVRQQFHDAKFMADTDLDPGCTLNKKIRNAQLAQYNFILVVGEKEKASG 683
           PV P  DEYA KV++Q HDA F+ D DLD G T+NKKIRNAQLAQYNFI VVGEKE A+G
Sbjct: 426 PVAPPFDEYADKVKKQIHDAGFLCDHDLDTGTTMNKKIRNAQLAQYNFIFVVGEKELANG 247

Query: 684 TVNIRTRDNKVHGERTVEETVRRLQQLKQTRSKQAEEEF 722
           TVN+RTRDNKVHGE +VE  ++R    K    + AE+ F
Sbjct: 246 TVNVRTRDNKVHGEHSVEHVIQRFSHFKTAFVQDAEDTF 130
>19083
          Length = 459

 Score =  241 bits (615), Expect = 8e-64,   Method: Compositional matrix adjust.
 Identities = 113/152 (74%), Positives = 127/152 (83%)
 Frame = -3

Query: 501 PEKFLGDIEIWNQAEKQLENSLNEFGEKWELNPGDGAFYGPKIDIQIKDAIGRYHQCATI 560
           P+K+LG++E WN AEK L  SLNEFG  W+ NPGDGAFYGPKIDI I DA+ R  QCATI
Sbjct: 454 PDKYLGELEQWNAAEKALAESLNEFGMPWKENPGDGAFYGPKIDITIMDALKRPFQCATI 275

Query: 561 QLDFQLPIRFNLTYVSHDGDDKKRPVIVHRAILGSVERMIAILTENYGGKWPFWLSPRQV 620
           QLDFQLPIRFNL Y++ DG +KKRPVI+HRAILGSVERMIAILTENY GKWPFWLSPRQV
Sbjct: 274 QLDFQLPIRFNLNYIADDG-EKKRPVIIHRAILGSVERMIAILTENYAGKWPFWLSPRQV 98

Query: 621 MVVPVGPTCDEYAQKVRQQFHDAKFMADTDLD 652
           MVVPVGP  DEYA+ VR Q H A FM+++D D
Sbjct: 97  MVVPVGPAYDEYAKSVRDQLHAAGFMSESDCD 2
>12449
          Length = 600

 Score = 60.1 bits (144), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 41/134 (30%), Positives = 61/134 (45%), Gaps = 12/134 (8%)
 Frame = -3

Query: 99  TTPYQIACGISQGLADNTVVAKVNKVVWDLDRPLETDCTLELLKFEDEE---AQAVYWHS 155
           +TP+  A  I + L   + +A VN   WD+ RPL   C LE + FED +   A   +W S
Sbjct: 415 STPFHCAMHIQELLMSRSALALVNGEPWDMHRPLTDSCELEFMHFEDPDPTPANEAFWRS 236

Query: 156 SAHIMGEAMERVYGG------CLCYGPPIENG-FYYDMYLEEGG--VSSNDFSSLETLCK 206
            + I+G  +E  +        C    P + +G F YD+ L  G    S+ +   L     
Sbjct: 235 CSFILGYVLENAFKDHHYVELCSFPKPNVHSGSFVYDVDLRLGDWKPSAKELDILGRTGF 56

Query: 207 KIIKEKQTFERLEV 220
           K+      FERL+V
Sbjct: 55  KLFFNNYPFERLDV 14
>06461
          Length = 1131

 Score = 33.5 bits (75), Expect = 0.34,   Method: Compositional matrix adjust.
 Identities = 30/125 (24%), Positives = 53/125 (42%), Gaps = 13/125 (10%)
 Frame = -3

Query: 570 FNLTYVSHDGDDKKRPVIVHRAILG-SVERM----IAILTENYGGKWPFWLSPRQVMVVP 624
           FN TY+    DD +    +H    G  V R+    + +L+     +WP  ++P QV ++P
Sbjct: 679 FNATYM----DDSESIKPIHMGCFGLGVTRILQATVEVLSRERQLRWPPLMAPYQVCIIP 512

Query: 625 -----VGPTCDEYAQKVRQQFHDAKFMAD---TDLDPGCTLNKKIRNAQLAQYNFILVVG 676
                    C   A+++         +A     D     ++ ++I  A    Y +I+VVG
Sbjct: 511 QKEGYQADACFRLAEELSDALCSLPHLAGEVLIDDRIKFSIGRRIYEASRLGYPYIIVVG 332

Query: 677 EKEKA 681
           +K  A
Sbjct: 331 KKALA 317
>28061
          Length = 493

 Score = 29.6 bits (65), Expect = 4.9,   Method: Composition-based stats.
 Identities = 13/44 (29%), Positives = 23/44 (52%), Gaps = 5/44 (11%)
 Frame = +1

Query: 263 PHVRHTGKIKTLKIHKNSSTYWEGKADMETLQ-----RIYGISF 301
           PH  HTG    L++H   +  W+   D+ T +     R++G+S+
Sbjct: 355 PHALHTGSPSALRLHSVVTVVWQLAHDIPTRRDVCCIRLWGLSW 486
>22318
          Length = 808

 Score = 29.3 bits (64), Expect = 6.5,   Method: Compositional matrix adjust.
 Identities = 16/45 (35%), Positives = 21/45 (46%)
 Frame = -3

Query: 608 GGKWPFWLSPRQVMVVPVGPTCDEYAQKVRQQFHDAKFMADTDLD 652
           GG WP WLS       P G     +++ V   F   +F+ DT LD
Sbjct: 167 GGTWPAWLS-----AAPDGTPSLCFSEYVLFPFQPPQFLQDTHLD 48
>19547
          Length = 617

 Score = 28.9 bits (63), Expect = 7.7,   Method: Compositional matrix adjust.
 Identities = 25/92 (27%), Positives = 38/92 (41%), Gaps = 1/92 (1%)
 Frame = -1

Query: 375 NIFNSRLWMTSGHWQHYSENMFSFEVEKEQFALKPMNCP-GHCLMFDHRPRSWRELPLRL 433
           N  +  +W  SG        +   + E   F L P +      L+  H P S+++LP  L
Sbjct: 614 NTCSRHIWKASGRXSLQERTVTLQDREGHHFCLGPTHEELVTSLVASHSPLSFQQLPQLL 435

Query: 434 ADFGVLHRNELSGALTGLTRVRRFQQDDAHIF 465
                  R+E+S    GL R R F+  D + F
Sbjct: 434 YQITRKFRDEMSPK-HGLLRGREFEMKDMYTF 342
>24754
          Length = 725

 Score = 28.5 bits (62), Expect = 9.4,   Method: Compositional matrix adjust.
 Identities = 11/31 (35%), Positives = 17/31 (54%)
 Frame = +3

Query: 164 MERVYGGCLCYGPPIENGFYYDMYLEEGGVS 194
           + +VYG  +C GP +     + +YLE  G S
Sbjct: 510 VSKVYGSSVCQGPRVWLTLRFQLYLESSGTS 602
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|33859604|ref|NP_035318.1| proteasome (prosome,
macropain) 26S subunit, ATPase 2 [Mus musculus]
         (475 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

07243                                                                 316   2e-86
19129                                                                 265   3e-71
07247                                                                 224   1e-69
01642                                                                 246   1e-65
23766                                                                 232   2e-61
02582                                                                 150   1e-36
03022                                                                 134   7e-32
12235                                                                 124   7e-29
00810                                                                  87   1e-17
20270                                                                  87   2e-17
38672                                                                  87   2e-17
37695                                                                  54   6e-14
26408                                                                  70   1e-12
25671                                                                  62   7e-10
02194                                                                  51   8e-07
26887                                                                  47   2e-05
17843                                                                  45   6e-05
06766                                                                  39   0.005
14413                                                                  37   0.014
01279                                                                  34   0.16 
30736                                                                  28   6.9  
>07243
          Length = 1112

 Score =  316 bits (809), Expect = 2e-86,   Method: Compositional matrix adjust.
 Identities = 155/311 (49%), Positives = 212/311 (68%)
 Frame = +1

Query: 148 SEDPKYIINVKQFAKFVVDLSDQVAPTDIEEGMRVGVDRNKYQIHIPLPPKIDPTVTMMQ 207
           +ED K+I+      ++VV    Q+    ++ G RV +D     I   LP ++DP V  M 
Sbjct: 1   TED-KFIVKATNGPRYVVGCRRQLDKAKLKSGTRVALDMTTLTIMRYLPREVDPLVYNMS 177

Query: 208 VEEKPDVTYSDVGGCKEQIEKLREVVETPLLHPERFVNLGIEPPKGVLLFGPPGTGKTLC 267
            E+  DVTYS +GG  EQI +LREV+E PLL+PE F+ +GI PPKG LL+GPPGTGKTL 
Sbjct: 178 HEDPGDVTYSAIGGLTEQIRELREVIELPLLNPELFLRVGITPPKGCLLYGPPGTGKTLL 357

Query: 268 ARAVANRTDACFIRVIGSELVQKYVGEGARMVRELFEMARTKKACLIFFDEIXXXXXXXX 327
           ARAVA++ DA F++V+ S +V KY+GE AR++RE+F  AR  + C+IF DEI        
Sbjct: 358 ARAVASQLDANFLKVVSSAIVDKYIGESARLIREMFNYARDHQPCIIFMDEIDAIGGRRF 537

Query: 328 XXXXXXXNEVQRTMLELINQLDGFDPRGNIKVLMATNRPDTLDPALMRPGRLDRKIEFSL 387
                   E+QRT++EL+NQ+DGFD  G +K++MATNRPDTLDPAL+RPGRLDRKIE  L
Sbjct: 538 SEGTSADREIQRTLMELLNQMDGFDSLGQVKMIMATNRPDTLDPALLRPGRLDRKIEIPL 717

Query: 388 PDLEGRTHIFKIHARSMSVERDIRFELLARLCPNSTGAEIRSVCTEAGMFAIRARRKIAT 447
           P+ + R  I KIHA  ++   +I +E + +L  N  GA++R+VCTEAG+FAIRA R+   
Sbjct: 718 PNEQARLEILKIHALIIAKHGEIDYEAIVKLSDNFNGADLRNVCTEAGLFAIRAEREYVI 897

Query: 448 EKDFLEAVNKV 458
           ++DF++AV KV
Sbjct: 898 QEDFMKAVRKV 930
>19129
          Length = 1020

 Score =  265 bits (677), Expect = 3e-71,   Method: Compositional matrix adjust.
 Identities = 133/242 (54%), Positives = 167/242 (69%)
 Frame = +1

Query: 152 KYIINVKQFAKFVVDLSDQVAPTDIEEGMRVGVDRNKYQIHIPLPPKIDPTVTMMQVEEK 211
           K ++ V    KFVVD+   +    +    RV +  + Y +H  LP K+DP V++M VE+ 
Sbjct: 292 KVLVKVHPEGKFVVDIDKNIDMNSVTPNCRVALRNDSYVLHKILPNKVDPLVSLMMVEKV 471

Query: 212 PDVTYSDVGGCKEQIEKLREVVETPLLHPERFVNLGIEPPKGVLLFGPPGTGKTLCARAV 271
           PD TY  VGG  +QI++++EV+E P+ HPE F  LGI  PKGVLL+GPPGTGKTL ARAV
Sbjct: 472 PDSTYEMVGGLDKQIKEIKEVIELPVKHPELFEALGIAQPKGVLLYGPPGTGKTLLARAV 651

Query: 272 ANRTDACFIRVIGSELVQKYVGEGARMVRELFEMARTKKACLIFFDEIXXXXXXXXXXXX 331
           A+ T+  FIRV GSELVQK++GEG+RMVRELF MAR     +IF DEI            
Sbjct: 652 AHHTECTFIRVSGSELVQKFIGEGSRMVRELFVMAREHAPSIIFMDEIDSIGSSRLEGGS 831

Query: 332 XXXNEVQRTMLELINQLDGFDPRGNIKVLMATNRPDTLDPALMRPGRLDRKIEFSLPDLE 391
              +EVQRTMLEL+NQLDGF+P+ NIKV+MATNR D LD AL+RPGR+DRKIEF  P+ E
Sbjct: 832 GGDSEVQRTMLELLNQLDGFEPKQNIKVIMATNRIDILDSALLRPGRIDRKIEFPPPNEE 1011

Query: 392 GR 393
            R
Sbjct: 1012AR 1017
>07247
          Length = 1753

 Score =  224 bits (572), Expect(2) = 1e-69,   Method: Compositional matrix adjust.
 Identities = 106/199 (53%), Positives = 142/199 (71%)
 Frame = -2

Query: 260  PGTGKTLCARAVANRTDACFIRVIGSELVQKYVGEGARMVRELFEMARTKKACLIFFDEI 319
            PGTGKTL ARAVA++ D  F++V+ S +V KY+GE AR++RE+F  AR  + C+IF DEI
Sbjct: 1407 PGTGKTLLARAVASQLDCNFLKVVSSAIVDKYIGESARLIREMFAFARDHEPCIIFMDEI 1228

Query: 320  XXXXXXXXXXXXXXXNEVQRTMLELINQLDGFDPRGNIKVLMATNRPDTLDPALMRPGRL 379
                            E+QRT++EL+NQ+DGFD  G +K++MATNRPDTLDPAL+RPGRL
Sbjct: 1227 DAIGGRRFSEGTSADREIQRTLMELLNQMDGFDALGQVKMIMATNRPDTLDPALLRPGRL 1048

Query: 380  DRKIEFSLPDLEGRTHIFKIHARSMSVERDIRFELLARLCPNSTGAEIRSVCTEAGMFAI 439
            DRKIE SLP+ + R  I KIHA  ++   +I +E + +L  +  GA++R+VCTEAGMFAI
Sbjct: 1047 DRKIEISLPNEQARLEILKIHANPIAKHGEIDWEAVVKLSEDFNGADLRNVCTEAGMFAI 868

Query: 440  RARRKIATEKDFLEAVNKV 458
            RA R    E+DF++AV KV
Sbjct: 867  RAERDYVIEEDFMKAVRKV 811

 Score = 57.4 bits (137), Expect(2) = 1e-69,   Method: Compositional matrix adjust.
 Identities = 25/50 (50%), Positives = 36/50 (72%)
 Frame = -1

Query: 199  IDPTVTMMQVEEKPDVTYSDVGGCKEQIEKLREVVETPLLHPERFVNLGI 248
            +DP V  M VE+  D+T++ +GG  EQ+ +LREV+E PLL+PE F  +GI
Sbjct: 1588 MDPLVYNMSVEDPGDITFNQIGGLGEQVRELREVIELPLLNPELFQRVGI 1439

 Score = 28.1 bits (61), Expect = 8.0,   Method: Compositional matrix adjust.
 Identities = 12/21 (57%), Positives = 12/21 (57%)
 Frame = -3

Query: 240  PERFVNLGIEPPKGVLLFGPP 260
            P      G  PPKG LLFGPP
Sbjct: 1466 PRAVPACGHHPPKGCLLFGPP 1404
>01642
          Length = 1406

 Score =  246 bits (629), Expect = 1e-65,   Method: Compositional matrix adjust.
 Identities = 124/267 (46%), Positives = 166/267 (62%)
 Frame = -1

Query: 194  PLPPKIDPTVTMMQVEEKPDVTYSDVGGCKEQIEKLREVVETPLLHPERFVNLGIEPPKG 253
            P P ++       ++   P   YSD+GG   Q +++RE VE PL H E +  +GI+PP+G
Sbjct: 1064 PSPQRLTAVSQCFKLMRSPT*XYSDIGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRG 885

Query: 254  VLLFGPPGTGKTLCARAVANRTDACFIRVIGSELVQKYVGEGARMVRELFEMARTKKACL 313
            VL++GPPG GKT+ A+AVA+ T A FIRV+GSE VQKY+GEG RMVR++F +A+     +
Sbjct: 884  VLMYGPPGCGKTMLAKAVAHHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAI 705

Query: 314  IFFDEIXXXXXXXXXXXXXXXNEVQRTMLELINQLDGFDPRGNIKVLMATNRPDTLDPAL 373
            IF DEI                EVQR +LEL+NQ+DGFD   N+KV+MATNR DTLDPAL
Sbjct: 704  IFIDEIDAIATKRFDAQTGADREVQRILLELLNQMDGFDQTVNVKVIMATNRADTLDPAL 525

Query: 374  MRPGRLDRKIEFSLPDLEGRTHIFKIHARSMSVERDIRFELLARLCPNSTGAEIRSVCTE 433
            +RPGRLDRKIEF LPD   +  IF      M++  ++  E         +GA+I ++C E
Sbjct: 524  LRPGRLDRKIEFPLPDRRQKRLIFSTITGKMNISEEVDLEDYVARPDKISGADINAICQE 345

Query: 434  AGMFAIRARRKIATEKDFLEAVNKVIK 460
            AGM A+R  R +   KDF +     IK
Sbjct: 344  AGMQAVRENRYVVLAKDFEKGYKNNIK 264
>23766
          Length = 1463

 Score =  232 bits (592), Expect = 2e-61,   Method: Compositional matrix adjust.
 Identities = 113/223 (50%), Positives = 153/223 (68%)
 Frame = +1

Query: 247 GIEPPKGVLLFGPPGTGKTLCARAVANRTDACFIRVIGSELVQKYVGEGARMVRELFEMA 306
           G + PKGV+L+GPPGTGKTL A+AVAN+T A F+RV+GSEL+QKY+G+G ++VRELF +A
Sbjct: 142 GNQAPKGVILYGPPGTGKTLLAKAVANQTSATFLRVVGSELIQKYLGDGPKLVRELFRVA 321

Query: 307 RTKKACLIFFDEIXXXXXXXXXXXXXXXNEVQRTMLELINQLDGFDPRGNIKVLMATNRP 366
                 ++F DEI                E+QRTMLEL+NQLDGFD RG++KV+MATNR 
Sbjct: 322 EEHAPSIVFIDEIDAVGTKRYESNSGGEREIQRTMLELLNQLDGFDSRGDVKVIMATNRI 501

Query: 367 DTLDPALMRPGRLDRKIEFSLPDLEGRTHIFKIHARSMSVERDIRFELLARLCPNSTGAE 426
           +TLDPAL+RPGR+DRKIEF LPD + +  IF IH   M++  D+  +       + +GA+
Sbjct: 502 ETLDPALIRPGRIDRKIEFPLPDEKTKRRIFTIHTSRMTLAGDVNIDDYVMSKDDLSGAD 681

Query: 427 IRSVCTEAGMFAIRARRKIATEKDFLEAVNKVIKSYAKFSATP 469
           I+++CTEAG+ A+R RR     +DF +A   V+  Y K   TP
Sbjct: 682 IKAICTEAGLLALRERRMKVRNEDFAKAKENVL--YRKNEGTP 804

 Score = 51.6 bits (122), Expect = 7e-07,   Method: Compositional matrix adjust.
 Identities = 29/80 (36%), Positives = 43/80 (53%), Gaps = 1/80 (1%)
 Frame = +2

Query: 201 PTVTMMQVEEK-PDVTYSDVGGCKEQIEKLREVVETPLLHPERFVNLGIEPPKGVLLFGP 259
           P VT+M+  EK P  TY+D+GG   QI++++E VE PL HPE +  +GI+  K +   G 
Sbjct: 2   PMVTVMKGWEKAPQETYADIGGLDTQIQEIKESVELPLTHPEYYEEMGIKHQKVLSCMGL 181

Query: 260 PGTGKTLCARAVANRTDACF 279
               K    + +  R    F
Sbjct: 182 QAQAKPCWPKLLPTRPRRLF 241
>02582
          Length = 1101

 Score =  150 bits (378), Expect = 1e-36,   Method: Compositional matrix adjust.
 Identities = 90/276 (32%), Positives = 138/276 (50%), Gaps = 34/276 (12%)
 Frame = +3

Query: 214 VTYSDVGGCKEQIEKLREVVETPLLHPERFVNLGIEPPKGVLLFGPPGTGKTLCARAVAN 273
           V ++D+GG      ++R+ VE PLL+P+ F  LG+   KGVLL+GPPG GKT  A+A A 
Sbjct: 132 VPWTDIGGLDLVKLQIRQAVEWPLLYPDTFQALGLPLTKGVLLYGPPGCGKTTLAQAAAT 311

Query: 274 RTDACFIRVIGSELVQKYVGEGARMVRELFEMARTKKACLIFFDEIXXXXXXXXXXXXXX 333
                F+ +  ++L   YVG+  + + E F+ AR     ++F DE+              
Sbjct: 312 ACHVTFLSLSCAQLYSPYVGDAEKKISETFQKARALAPSILFLDEM-DAIVGKRSDSSLG 488

Query: 334 XNEVQRTMLELINQLDGFDPR--------------------------------GNIKVLM 361
               +R +  L+N++DG   R                                 ++ V+ 
Sbjct: 489 SGVSERVLSALLNEMDGIGVRLDDKSDSREMEIEGSSDHTPQVRQHAVKEAHDRHVLVVA 668

Query: 362 ATNRPDTLDPALMRPGRLDRKIEFSLPDLEGRTHIFKIHARSMSVERDIRFELLARLCPN 421
           ATNRPD LDPAL+RPGR+DR I    PD++GR   F IH R M + +D+  + LA L   
Sbjct: 669 ATNRPDMLDPALLRPGRMDRLIYVPPPDVQGRLQSFTIHTRKMPLGKDVDVKQLADLTAG 848

Query: 422 STGAEIRSVCTEAGMFAIR--ARRKIATEKDFLEAV 455
            TGA+I+++C E G+ A++     +   +  FL A+
Sbjct: 849 YTGADIKTLCNEVGLLALKESMSAECVNQDHFLNAI 956
>03022
          Length = 2255

 Score =  134 bits (337), Expect = 7e-32,   Method: Compositional matrix adjust.
 Identities = 80/231 (34%), Positives = 118/231 (51%), Gaps = 2/231 (0%)
 Frame = +2

Query: 212  PDVTYSDVGGCKEQIEKLREVVETPLLHPERFVNLGIEPPKGVLLFGPPGTGKTLCARAV 271
            P  T+ DVG       +L++ +   +  PE     G+    G++L GPPG GKTL A+A+
Sbjct: 1412 PTTTWEDVGALSNVRAQLKDSILCRIHDPEVSSAFGLPTNSGIILVGPPGCGKTLVAKAM 1591

Query: 272  ANRTDACFIRVIGSELVQKYVGEGARMVRELFEMARTKKACLIFFDEIXXXXXXXXXXXX 331
            AN     FI + G EL+ KYVGE  R +RE F+ A+    CLIFFDE+            
Sbjct: 1592 ANEAGLNFIYIKGPELLDKYVGESERNLREKFDKAQACAPCLIFFDEM--DTLCSNRQNN 1765

Query: 332  XXXNEVQRTMLELINQLDGFDPRGNIKVLMATNRPDTLDPALMRPGRLDRKIEFSLPDLE 391
               N  +    +L+  +DG   R  + V+ ATN  + +DPAL RPGR DRKI   LPD +
Sbjct: 1766 DGSNVGKSVTNQLLALMDGCGERSQVYVMGATNIIENVDPALQRPGRFDRKIFIGLPDTD 1945

Query: 392  GRTHIFKIHARSMSVER--DIRFELLARLCPNSTGAEIRSVCTEAGMFAIR 440
            GR  I +   +  S  +      + LA+     +GA+++ +  EA   A++
Sbjct: 1946 GRLDILRALTKGGSQRKLESCDMQQLAQDTEGFSGADLKHLVNEASTIALK 2098

 Score = 40.8 bits (94), Expect(2) = 2e-07,   Method: Compositional matrix adjust.
 Identities = 26/110 (23%), Positives = 52/110 (47%), Gaps = 2/110 (1%)
 Frame = +1

Query: 212 PDVTYSDVGGCKEQIEKLREVVETPLL--HPERFVNLGIEPPKGVLLFGPPGTGKTLCAR 269
           P  T  D GG  + + +L    E  L   + +       +  +  LL+GP G+GK   A 
Sbjct: 514 PTATLDDFGGSNKLLAELDSDFEEILYSDYCQYASACDQKACRRYLLYGPRGSGKRFLAE 693

Query: 270 AVANRTDACFIRVIGSELVQKYVGEGARMVRELFEMARTKKACLIFFDEI 319
            +A +     ++   + L+    G+  + VR+LF+ A ++  C+++ ++I
Sbjct: 694 CIAGQLKLPLLKPKINTLISGVSGDSEQRVRDLFDQAVSQAPCVLYLEDI 843

 Score = 31.6 bits (70), Expect(2) = 2e-07,   Method: Compositional matrix adjust.
 Identities = 22/90 (24%), Positives = 40/90 (44%)
 Frame = +2

Query: 356  NIKVLMATNRPDTLDPALMRPGRLDRKIEFSLPDLEGRTHIFKIHARSMSVERDIRFELL 415
            N+ V+  T+R + +   L  PGR   K    +PD   R  + +      ++   ++ + L
Sbjct: 953  NVVVVATTSRIEAVHRDLRIPGRFMEK-ALGMPDEGSREGLLQRLCSRYTLSPHLKLKTL 1129

Query: 416  ARLCPNSTGAEIRSVCTEAGMFAIRARRKI 445
            ARL P     ++R++   A   A R  R +
Sbjct: 1130 ARLTPGFVAGDLRALVHGAFSTAFRRVRNL 1219
>12235
          Length = 1749

 Score =  124 bits (311), Expect = 7e-29,   Method: Compositional matrix adjust.
 Identities = 68/188 (36%), Positives = 102/188 (54%), Gaps = 2/188 (1%)
 Frame = +1

Query: 279 FIRVIGSELVQKYVGEGARMVRELFEMARTKKACLIFFDEIXXXXXXXXXXXXXXXNEVQ 338
           FI V GSE ++ +VG G   VR++F  AR    C++F DEI               +E +
Sbjct: 16  FITVSGSEFLEMFVGVGPSRVRDMFATARKNAPCILFVDEIDAVGRKRSGRNFGGQSEQE 195

Query: 339 RTMLELINQLDGFDPRGNIKVLMATNRPDTLDPALMRPGRLDRKIEFSLPDLEGRTHIFK 398
            T+ +L+ ++DGF+ +  + VL ATNR D LD AL+RPGR DR+I   LPD++ R  IFK
Sbjct: 196 NTLNQLLVEMDGFNTQTGVVVLAATNRVDILDAALLRPGRFDRQIFVPLPDIKXRASIFK 375

Query: 399 IHARSMSVE--RDIRFELLARLCPNSTGAEIRSVCTEAGMFAIRARRKIATEKDFLEAVN 456
           +H   +  E  ++     +A L P  +GA+I +VC EA + A R          F +A+ 
Sbjct: 376 VHLDPLKTEVNKNDLARKMAALTPGFSGADIANVCNEAALIAARDLNTSIHMTHFEQAIE 555

Query: 457 KVIKSYAK 464
           +V+    K
Sbjct: 556 RVVAGLEK 579
>00810
          Length = 1431

 Score = 87.4 bits (215), Expect = 1e-17,   Method: Compositional matrix adjust.
 Identities = 67/218 (30%), Positives = 104/218 (47%), Gaps = 3/218 (1%)
 Frame = -3

Query: 226  IEKLREVVETPLLHPERFVNLGI-EPPKGVLLFGPPGTGKTLCARAVANRTDACFIRVIG 284
            I+ ++E V  P    + F +  + +PPKGVLL GPPG GKT+ A+A A    A FI +  
Sbjct: 1417 IQDVKETVILPFKRADLFRHSSLLQPPKGVLLHGPPGCGKTMIAKATAKAAGARFINLQV 1238

Query: 285  SELVQKYVGEGARMVRELFEMARTKKACLIFFDEIXXXXXXXXXXXXXXXNEVQRTMLEL 344
            S LV K+ GE  +    +F +A   +  +IF DEI                 ++   +  
Sbjct: 1237 SSLVDKWYGESQKRAEAVFSLAIKLQPTIIFIDEIDSFLRSRTSTDHEATAMIKTQFMSF 1058

Query: 345  INQLDGFDPRGNIKVLMATNRPDTLDPALMRPGRLDRKIEFSLPDLEGRTHIFKIHARSM 404
             + L   DP   + V+ ATNRP  +D A++R  R+       LP    R  IF +    +
Sbjct: 1057 WDGLMT-DPDCRVMVMGATNRPQDVDAAILR--RMPSMFHIGLPGPAQRRSIFNL---IL 896

Query: 405  SVER--DIRFELLARLCPNSTGAEIRSVCTEAGMFAIR 440
            S ER   + ++ LA +    +G++IR VC  A +  + 
Sbjct: 895  SKERIDALNYDELAEMTDGFSGSDIREVCRAAAVATVH 782
>20270
          Length = 542

 Score = 86.7 bits (213), Expect = 2e-17,   Method: Compositional matrix adjust.
 Identities = 55/157 (35%), Positives = 82/157 (52%), Gaps = 2/157 (1%)
 Frame = -3

Query: 221 GCKEQIEKLREVVETPLLHPERFVNLGIEPPKGVLLFGPPGTGKTLCARAVANR-TDACF 279
           GC E    L   + +P LH E       +P +G+LL+GPPGTGK+  A+AVA    ++ F
Sbjct: 450 GCFEGSRHLACQI-SPSLHREE------KPWRGILLYGPPGTGKSYLAKAVATEANNSTF 292

Query: 280 IRVIGSELVQKYVGEGARMVRELFEMARTKKACLIFFDEIXXXXXXXXXXXXXXXNEVQR 339
             V  S+LV K++GE  ++V+ LF++AR  +  +IF DE+                  +R
Sbjct: 291 FSVSSSDLVSKWLGESEKLVKTLFQLARENQPSIIFIDEV---DALCGSRSENESESARR 121

Query: 340 TMLELINQLDGF-DPRGNIKVLMATNRPDTLDPALMR 375
              E + Q+ G  +    + VL ATN P TLD A+ R
Sbjct: 120 IKTEFLVQMQGVGNDNTGVLVLGATNIPWTLDSAIRR 10
>38672
          Length = 730

 Score = 86.7 bits (213), Expect = 2e-17,   Method: Compositional matrix adjust.
 Identities = 46/130 (35%), Positives = 79/130 (60%), Gaps = 2/130 (1%)
 Frame = -3

Query: 336 EVQRTML-ELINQLDGFDPRGNIKVLMATNRPDTLDPALMRPGRLDRKIEFSLPDLEGRT 394
           EV+R ++ +L+  +DG   R ++ V+ ATNRP+++D AL R GR DR+++  +PD  GR 
Sbjct: 596 EVERRIVSQLLTLMDGLKQRSHVIVMAATNRPNSVDAALRRFGRFDREVDIGIPDATGRL 417

Query: 395 HIFKIHARSMSVERDIRFELLARLCPNSTGAEIRSVCTEAGMFAIRARRK-IATEKDFLE 453
            I +IH ++M +  D+  E +A       GA++ ++C+EA +  IR +   I  E D ++
Sbjct: 416 EILRIHTKNMKLADDVDLEQVASETHGHVGADVAALCSEAALQQIREKMDLIDLEDDTID 237

Query: 454 AVNKVIKSYA 463
           A  +V+ S A
Sbjct: 236 A--EVLDSLA 213

 Score = 57.0 bits (136), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 28/93 (30%), Positives = 53/93 (56%)
 Frame = -3

Query: 164 VVDLSDQVAPTDIEEGMRVGVDRNKYQIHIPLPPKIDPTVTMMQVEEKPDVTYSDVGGCK 223
           ++DL D     ++ + + V +D  ++ +      K +P+       E P+V++ DVGG +
Sbjct: 266 LIDLEDDTIDAEVLDSLAVTMDDFRWAL-----GKSNPSALRETCVEVPNVSWEDVGGLE 102

Query: 224 EQIEKLREVVETPLLHPERFVNLGIEPPKGVLL 256
              ++L+E+V+ P+ HPE+F+  G+ P KGVL 
Sbjct: 101 NVKKELQELVQYPVEHPEKFLKFGMTPSKGVLF 3
>37695
          Length = 156

 Score = 53.5 bits (127), Expect(2) = 6e-14,   Method: Composition-based stats.
 Identities = 24/26 (92%), Positives = 26/26 (100%)
 Frame = +3

Query: 431 CTEAGMFAIRARRKIATEKDFLEAVN 456
           CTEAGMFAIRARRK+ATEKDFL+AVN
Sbjct: 9   CTEAGMFAIRARRKMATEKDFLDAVN 86

 Score = 41.6 bits (96), Expect(2) = 6e-14,   Method: Composition-based stats.
 Identities = 17/18 (94%), Positives = 18/18 (100%)
 Frame = +1

Query: 458 VIKSYAKFSATPRYMTYN 475
           VIK+YAKFSATPRYMTYN
Sbjct: 91  VIKAYAKFSATPRYMTYN 144
>26408
          Length = 463

 Score = 70.5 bits (171), Expect = 1e-12,   Method: Composition-based stats.
 Identities = 32/49 (65%), Positives = 40/49 (81%)
 Frame = +1

Query: 227 EKLREVVETPLLHPERFVNLGIEPPKGVLLFGPPGTGKTLCARAVANRT 275
           ++++EV+E P+ HPE F  LGI  PKGVLL+GPPGTGKTL ARAVA+ T
Sbjct: 292 QRIKEVIELPVKHPELFDALGIAQPKGVLLYGPPGTGKTLLARAVAHHT 438

 Score = 52.0 bits (123), Expect = 5e-07,   Method: Composition-based stats.
 Identities = 26/70 (37%), Positives = 37/70 (52%)
 Frame = +2

Query: 167 LSDQVAPTDIEEGMRVGVDRNKYQIHIPLPPKIDPTVTMMQVEEKPDVTYSDVGGCKEQI 226
           L   +   D+    RV +    Y +H  LP K+DP V++M VE+ PD TY  VGG  +QI
Sbjct: 113 LDKNIDINDVTPNCRVALRNESYTLHKILPNKVDPLVSLMMVEKVPDSTYEMVGGLDKQI 292

Query: 227 EKLREVVETP 236
           ++ R     P
Sbjct: 293 KESRR*SNCP 322
>25671
          Length = 441

 Score = 61.6 bits (148), Expect = 7e-10,   Method: Composition-based stats.
 Identities = 42/110 (38%), Positives = 51/110 (46%), Gaps = 5/110 (4%)
 Frame = +2

Query: 262 TGKTLCARAVANRTDACFIRVIGSELVQKYVGEGARMVRELFEMARTKKACLIFFDEIXX 321
           TGKT+ A+AVA      F  V  S L  KY GE  ++VR LFEMA       IF DEI  
Sbjct: 2   TGKTMLAKAVATECGTTFFNVSTSSLANKYRGESEKLVRLLFEMAHFYAPSTIFIDEIDS 181

Query: 322 XXXXXXXXXXXXXNEVQRTMLELINQLDGF-----DPRGNIKVLMATNRP 366
                        +  +R   EL+ Q+DG      DP   + VL ATN P
Sbjct: 182 ICSKRGSDSEHEAS--RRVKSELLVQMDGVGVTNDDPSKAVMVLAATNFP 325
>02194
          Length = 1891

 Score = 51.2 bits (121), Expect = 8e-07,   Method: Compositional matrix adjust.
 Identities = 44/144 (30%), Positives = 61/144 (42%), Gaps = 1/144 (0%)
 Frame = -1

Query: 240  PERFVNLGIEPPKGVLLFGPPGTGKTLCARAVANRTDACFIRVIGSELVQKYVGEGARMV 299
            P  +++ GI   +G LL+GPPG GK+    A+A   D     +    L +K  G     +
Sbjct: 1531 PRWYMDRGIPYRRGYLLYGPPGCGKSSYIMALAGALD---YNICVLNLSEK--GLSDDRL 1367

Query: 300  RELFEMARTKKACLI-FFDEIXXXXXXXXXXXXXXXNEVQRTMLELINQLDGFDPRGNIK 358
              L  +A  +   L+   D                    + T   L+N LDG        
Sbjct: 1366 NHLLTVAPEQSIILLEDVDAAFLSRDLSKENPAMYQGMGRLTFSGLLNALDGVASAEARI 1187

Query: 359  VLMATNRPDTLDPALMRPGRLDRK 382
            V M TN  D LDPAL+RPGR+D K
Sbjct: 1186 VFMTTNYLDRLDPALIRPGRVDMK 1115
>26887
          Length = 410

 Score = 46.6 bits (109), Expect = 2e-05,   Method: Composition-based stats.
 Identities = 20/28 (71%), Positives = 25/28 (89%)
 Frame = -3

Query: 336 EVQRTMLELINQLDGFDPRGNIKVLMAT 363
           E+QRTMLEL+NQLDGFD RG++KV + T
Sbjct: 138 EIQRTMLELLNQLDGFDSRGDVKVHLXT 55
>17843
          Length = 772

 Score = 45.1 bits (105), Expect = 6e-05,   Method: Compositional matrix adjust.
 Identities = 37/164 (22%), Positives = 68/164 (41%), Gaps = 16/164 (9%)
 Frame = +1

Query: 227 EKLREVVETPLLHPERFVNLGI-EPPKGVLLFGPPGTGKTLCARAVANRTD-------AC 278
           E+L     T LL  ++ VN  I    + +LL GPPGTGKT   +A+A++         +C
Sbjct: 109 ERLLNYATTTLLFSDKHVNSSIISWNRVILLHGPPGTGKTTLCKALAHKLCIRLSHRFSC 288

Query: 279 --FIRVIGSELVQKYVGEGARMVRELFE-----MARTKKACLIFFDEIXXXXXXXXXXXX 331
              + +    L  K+  E  ++V ++F+     M   +    +  DE+            
Sbjct: 289 GQLVEINSHSLFSKWFSESGKLVTKMFQRLHDYMVDPELLVCVLIDEVESLTAARKSCLN 468

Query: 332 XXX-NEVQRTMLELINQLDGFDPRGNIKVLMATNRPDTLDPALM 374
               ++  R +  ++ Q+D      N  +L  +N    +D A +
Sbjct: 469 GNEPSDAIRVVNAVLTQIDQLKKFANCLILTTSNITGAIDLAFV 600
>06766
          Length = 976

 Score = 38.9 bits (89), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 25/84 (29%), Positives = 41/84 (48%), Gaps = 2/84 (2%)
 Frame = +2

Query: 378 RLDRKIEFSLPDLEGRTHIFKIHARSMSVERDIRFELLARLCPNSTGAEIRSVCTEAGMF 437
           RLD+ I   LPD + R  I K + R   + +++    +A++    +GA++  +C  A   
Sbjct: 2   RLDQLIYIPLPDDKSREAILKANLRKSPLAKEVDLTYIAKVTQGFSGADLTEICQRACKL 181

Query: 438 AIRA--RRKIATEKDFLEAVNKVI 459
           AIR     +I  EKD  E  N  +
Sbjct: 182 AIRQAIEAEIRREKDRAENQNSAM 253
>14413
          Length = 826

 Score = 37.4 bits (85), Expect = 0.014,   Method: Compositional matrix adjust.
 Identities = 44/190 (23%), Positives = 73/190 (38%), Gaps = 24/190 (12%)
 Frame = +2

Query: 265 TLC---ARAVANRTDACF-----IRVIGSELVQKYVGEGARMVRELF----EMARTKKAC 312
           +LC   A  +A RT   F     + +    L  K+  E  ++V  LF    E+A  K   
Sbjct: 8   SLCKALAEKLAIRTQNSFAYTHLVEINSHSLFSKWFSESGKLVARLFGKIGELATDKNNL 187

Query: 313 L-IFFDEIXXXXXXXXXXXXXXXNEVQRTMLELINQLDGFDPRGNIKVLMATNRPDTLDP 371
           + +  DE+                +  R +  ++ QLD      N+ +L  +N   ++D 
Sbjct: 188 VCVLIDEVESLAYARSAMSSNEPRDAMRVVNAVLTQLDEIKACPNVLILATSNLAQSIDL 367

Query: 372 ALMRPGRLDRKIEFSLPDLEGRTHIFKIHARSMSVERDIRFE-----------LLARLCP 420
           A +   R D +    LPD    + I+K     + V   +R E            L+ L  
Sbjct: 368 AFL--DRADIRQFIGLPDPLAISSIYKSMLTELMVRGIVRTEELETSEADYKITLSNLAA 541

Query: 421 NSTGAEIRSV 430
           NSTG   R++
Sbjct: 542 NSTGLSGRTL 571
>01279
          Length = 2183

 Score = 33.9 bits (76), Expect = 0.16,   Method: Compositional matrix adjust.
 Identities = 18/38 (47%), Positives = 23/38 (60%), Gaps = 2/38 (5%)
 Frame = -3

Query: 252  KGVLLFGPPGTGKTLCARAVANR--TDACFIRVIGSEL 287
            + VLL GPPGTGKT  A A+A        F  ++GSE+
Sbjct: 1914 RAVLLAGPPGTGKTAIALAIAQELGNKVPFCPMVGSEV 1801
>30736
          Length = 520

 Score = 28.5 bits (62), Expect = 6.9,   Method: Compositional matrix adjust.
 Identities = 20/78 (25%), Positives = 38/78 (48%), Gaps = 2/78 (2%)
 Frame = -2

Query: 207 QVEEKPD--VTYSDVGGCKEQIEKLREVVETPLLHPERFVNLGIEPPKGVLLFGPPGTGK 264
           +V+ KP+  V++ D   C    E + + ++ P  +    +     PP  + + GPP +GK
Sbjct: 252 RVQGKPEFAVSFLDKIYCLSSHEAMEKFLKNPRPY---LLPAQPRPPCKLAVLGPPLSGK 82

Query: 265 TLCARAVANRTDACFIRV 282
           T     +AN+  A  ++V
Sbjct: 81  TTLCHLLANKYGAKVLKV 28
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|117956399|ref|NP_109620.2| LPS-responsive beige-like
anchor isoform alpha [Mus musculus]
         (2854 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

00139                                                                 174   4e-86
27225                                                                 159   2e-38
34256                                                                  89   8e-33
19571                                                                  86   2e-16
30256                                                                  45   3e-04
21105                                                                  44   0.001
00561                                                                  42   0.004
18853                                                                  38   0.070
18981                                                                  36   0.18 
27465                                                                  36   0.25 
04088                                                                  35   0.39 
02147                                                                  33   1.9  
17598                                                                  32   2.7  
14859                                                                  32   4.7  
>00139
          Length = 1653

 Score =  174 bits (441), Expect(2) = 4e-86,   Method: Compositional matrix adjust.
 Identities = 83/172 (48%), Positives = 121/172 (70%), Gaps = 9/172 (5%)
 Frame = +2

Query: 1255 LKASTSTEAPQPQRHGLEISRQQEQTAQGTAPDAV----DQQRR-----DSRSTMFRIPE 1305
            L  ST +E   PQ+   E +R Q         +A     D+Q R       R+  FRIPE
Sbjct: 590  LPPSTRSEPKDPQKTSPESARHQPAGVHRKPSNASRTGEDRQGRAIFSPGPRAPPFRIPE 769

Query: 1306 FKWSQMHQRLLTDLLFSIETDIQMWRSHSTKTVMDFVNSSDNVIFVHNTIHLISQVMDNM 1365
            F+WS +HQ+LL+DLLF++ETD+Q+W+SHS+K V+DFVN+S+N I+V N  H+ISQ+ DN+
Sbjct: 770  FRWSYLHQKLLSDLLFAVETDVQVWKSHSSKNVIDFVNASENHIYVVNVTHMISQLADNL 949

Query: 1366 VMACGGILPLLSAATSATHELENIEPTQGLSIEASVTFLQRLISLVDVLIFA 1417
            + +CGG+LPLL+AATS   E++ +EP QGLSIE +V+ LQR++++ D+L+FA
Sbjct: 950  ITSCGGLLPLLAAATSPNGEIDILEPNQGLSIEQAVSILQRIMAMTDILVFA 1105

 Score =  165 bits (417), Expect(2) = 4e-86,   Method: Compositional matrix adjust.
 Identities = 84/151 (55%), Positives = 102/151 (67%), Gaps = 15/151 (9%)
 Frame = +3

Query: 1418 SSLGFTEIEAEKNMSSGGILRQCLRLVCAVAVRNCLECQQH---------------SQLK 1462
            SS  F E+E EKNM SGGILRQCLRLVC  AVRNCLEC+                 +   
Sbjct: 1107 SSTNFAELEQEKNMPSGGILRQCLRLVCTAAVRNCLECRHRYSRPPSEPPSPGGSSTSGA 1286

Query: 1463 ARGDTAKSSKTIHSLIPMGKSAAKSPVDIVTGGISPVRDLDRLLQDMDINRLRAVVFRDI 1522
            A G        I SLI     + K+ V+ + G ++P++D ++LLQDMDINRLRAVV+RD+
Sbjct: 1287 AGGKPVNGVDPIQSLIGGSHPSTKNIVENLAGQVAPIKDPEKLLQDMDINRLRAVVYRDV 1466

Query: 1523 EDSKQAQFLALAVVYFISVLMVSKYRDILEP 1553
            E++KQAQFLALA+VYF SVLMVSKYRDILEP
Sbjct: 1467 EETKQAQFLALAIVYFTSVLMVSKYRDILEP 1559

 Score = 89.7 bits (221), Expect = 2e-17,   Method: Compositional matrix adjust.
 Identities = 38/78 (48%), Positives = 59/78 (75%), Gaps = 1/78 (1%)
 Frame = +2

Query: 880 NSDEQKITEMVYAIFRILLYHAVKYEWGGWRVWVDTLSITHSKVTFEIHKENLANIFRE- 938
           NS++QKIT+MV A+FR+LL+HA+K+E+GGWRVW+DTL+I HSKV FE   ++++ ++ + 
Sbjct: 2   NSEQQKITDMVMALFRMLLHHAIKFEFGGWRVWIDTLAILHSKVAFEDFNKHMSKMYHQY 181

Query: 939 EQRKGDEETGPCSSSLVP 956
           EQ++ D+   P      P
Sbjct: 182 EQQRTDDIVDPSERQQRP 235
>27225
          Length = 391

 Score =  159 bits (401), Expect = 2e-38,   Method: Compositional matrix adjust.
 Identities = 71/127 (55%), Positives = 96/127 (75%)
 Frame = +2

Query: 618 MHTLKYYYWAVNPQDRSGITPKGLDGPRPNQKEILSLRAFLLMFIKQLVMKDSGVKEDEL 677
           MH+LK+YYW V+PQDRSGI PKGLDG RP   EI+ LR+F+L+++++L++K  G+ EDEL
Sbjct: 11  MHSLKFYYWVVSPQDRSGIIPKGLDGARPTHDEIVKLRSFMLLYLRELIVKGQGILEDEL 190

Query: 678 QAILNYLLTMHEDDNLMDVLQLLVALMAEHPNSMIPAFDQRNGLRVIYKLLASKSEGIRV 737
           Q++LNYL T+HEDDN+ DVL+LLV LMA+HP SM+PAFD+        +      E IR+
Sbjct: 191 QSMLNYLTTLHEDDNIQDVLELLVELMAQHPASMVPAFDREERHHHCLQAAGIAEEDIRL 370

Query: 738 QALKALG 744
            AL+ LG
Sbjct: 371 LALRLLG 391
>34256
          Length = 485

 Score = 88.6 bits (218), Expect(2) = 8e-33,   Method: Compositional matrix adjust.
 Identities = 51/125 (40%), Positives = 70/125 (56%), Gaps = 9/125 (7%)
 Frame = -1

Query: 1971 GSSAVSRP---REFWRLDYWEDDLXXXXXFVRNPLGSTHPEATLKTAVEHAADEDILAKG 2027
            G  A  +P    EFW+LD WEDD       VRNPLGSTH +ATLK A+EH A ED + + 
Sbjct: 371  GHGARQQPVLNNEFWKLDVWEDDSRRRRRLVRNPLGSTHSQATLKAAIEHGATEDAINQA 192

Query: 2028 KQSIKSQALGNQNSENEALLEGDDDTLSSVDEKDLE------NLAGPVSLSTPAQLVAPS 2081
            +++  +     +  + E     D++ +  ++EKD E         GPV+LST  +LVAP 
Sbjct: 191  REAFHAHLSHLRKVQKEITDYTDEELM--MEEKDFEPEFSGHYCVGPVALSTACKLVAPG 18

Query: 2082 VVVKG 2086
            V VKG
Sbjct: 17   VSVKG 3

 Score = 72.8 bits (177), Expect(2) = 8e-33,   Method: Composition-based stats.
 Identities = 30/46 (65%), Positives = 39/46 (84%)
 Frame = -3

Query: 1931 REEEKMCDHLIRAAKYRDHVTATQLIQKIINLLTDKHGAWGSSAVS 1976
            REEEK+CDHLI++AK RDH  A +L +K+IN+LT+KHGAWG +A S
Sbjct: 483  REEEKLCDHLIKSAKRRDHSVAYKLKEKVINILTNKHGAWGQAATS 346
>19571
          Length = 457

 Score = 86.3 bits (212), Expect = 2e-16,   Method: Composition-based stats.
 Identities = 53/156 (33%), Positives = 75/156 (48%), Gaps = 4/156 (2%)
 Frame = +2

Query: 2679 TPRAILTGHDYEITCAAVCAELGLVLSGSQEGPCLIHSMNGDLLRTLEGPENCLKP---- 2734
            TP+A+LTGH  E+TC  V AELG+V+SGS+ GP L    +G        P     P    
Sbjct: 2    TPKAVLTGHQAEVTCLGVIAELGIVVSGSKRGPVLGAHTDGRPPAIARPPRQLPVPPSHH 181

Query: 2735 KLIQASREGHCVIFYENGCFCTFSVNGKLQATVETDDHIRAIQLSRDGQYLLTGGDNGVV 2794
             L  +   GH       G         +  A      +++   LSRDGQY++  GD GV 
Sbjct: 182  HLP*SLHPGH----LRQGPRLFLHRQRQAAALHAPQSNLQCQTLSRDGQYMIVSGDAGVW 349

Query: 2795 IVRQVSDLKQLFAYPGCDAGIRAMALSFDQRCIISG 2830
                  D   L+ +P CD+ IR++AL+ D +  I+G
Sbjct: 350  RCGATHDFTLLYTFPQCDSSIRSLALTHDHKFXIAG 457
>30256
          Length = 961

 Score = 45.4 bits (106), Expect = 3e-04,   Method: Composition-based stats.
 Identities = 22/59 (37%), Positives = 34/59 (57%)
 Frame = +3

Query: 2602 LVCGFWDKSFRVYSTDTGKLIQVVFGHWDVVTCLARSESYIGGNCYILSGSRDATLLLW 2660
            ++ G  D+S +V++ DTG     ++GH   V CL+ S         ++SGSRDATL +W
Sbjct: 81   VISGSTDRSLKVWNADTGVCTHTLYGHSSTVRCLSLSGK------KVVSGSRDATLRVW 239

 Score = 35.0 bits (79), Expect = 0.40,   Method: Composition-based stats.
 Identities = 34/145 (23%), Positives = 63/145 (43%), Gaps = 2/145 (1%)
 Frame = +3

Query: 2583 QSIQVHS-QCFVITSDNRYILVCGFWDKSFRVYSTDTGKLIQVVFGHWDVVTCLARSESY 2641
             ++Q H+ + + +  D  Y+ V G  D S RV+    GKL+  + GH  + + L   ++ 
Sbjct: 384  HTLQGHTNRVYSLQFDGVYV-VSGSLDTSIRVWDVRCGKLVHTLMGHQSLTSGLELKDN- 557

Query: 2642 IGGNCYILSGSRDATLLLWYWNGKSSGIGDNPGGETATPRAILTGHDYEITCAAVCAELG 2701
                  ++SG+ D+T+ +W          D   G+          H   +TC     +  
Sbjct: 558  -----LLVSGNADSTVKVW----------DVHTGKCLQTLLGPNKHRSAVTCLQFNKK-- 686

Query: 2702 LVLSGSQEGPCLIHSMN-GDLLRTL 2725
             V++ S +G   +  +N GD +R L
Sbjct: 687  FVVTCSDDGTVKLWDLNTGDFIRNL 761
>21105
          Length = 650

 Score = 43.5 bits (101), Expect = 0.001,   Method: Composition-based stats.
 Identities = 23/66 (34%), Positives = 35/66 (53%)
 Frame = +1

Query: 2601 ILVCGFWDKSFRVYSTDTGKLIQVVFGHWDVVTCLARSESYIGGNCYILSGSRDATLLLW 2660
            I +    D+  R +  +TGKLI  +  H D VT LA   + +    Y+LSGS D ++ LW
Sbjct: 106  ITITAHEDRHIRFFDNNTGKLIHAMVAHLDSVTSLAVDPNGL----YLLSGSHDCSIRLW 273

Query: 2661 YWNGKS 2666
              + K+
Sbjct: 274  NLDSKT 291
>00561
          Length = 1003

 Score = 42.0 bits (97), Expect = 0.004,   Method: Composition-based stats.
 Identities = 26/68 (38%), Positives = 36/68 (52%)
 Frame = -3

Query: 2593 VITSDNRYILVCGFWDKSFRVYSTDTGKLIQVVFGHWDVVTCLARSESYIGGNCYILSGS 2652
            V++SD  Y L  G WD++ R++    GK  +   GH   V  +A S      N  I+SGS
Sbjct: 845  VLSSDGNYAL-SGSWDQTLRLWDLAAGKTTRRFEGHTKDVLSVAFSAD----NRQIVSGS 681

Query: 2653 RDATLLLW 2660
            RD T+ LW
Sbjct: 680  RDKTIKLW 657
>18853
          Length = 444

 Score = 37.7 bits (86), Expect = 0.070,   Method: Compositional matrix adjust.
 Identities = 23/74 (31%), Positives = 36/74 (48%), Gaps = 2/74 (2%)
 Frame = +1

Query: 1244 SSVASDTERFELKASTSTEAPQPQ--RHGLEISRQQEQTAQGTAPDAVDQQRRDSRSTMF 1301
            +SV S T R  L AS +  AP+P        +  +Q   ++G  PD V+  R+  R +  
Sbjct: 214  TSVCSQTARTALSASINPPAPKPAGAHSSCGVLIRQHLISKGWIPDVVETVRQGKRHSTL 393

Query: 1302 RIPEFKWSQMHQRL 1315
            R+ + KW+   Q L
Sbjct: 394  RVYDAKWNMFAQGL 435
>18981
          Length = 407

 Score = 36.2 bits (82), Expect = 0.18,   Method: Composition-based stats.
 Identities = 24/99 (24%), Positives = 40/99 (40%)
 Frame = -2

Query: 2602 LVCGFWDKSFRVYSTDTGKLIQVVFGHWDVVTCLARSESYIGGNCYILSGSRDATLLLWY 2661
            +V G WDK+  V+  DTG+ +  + GH + +T +   E         +SGS D  +  W 
Sbjct: 259  VVSGSWDKTLIVWEVDTGRPVHQLHGHTEAITAVQFDEG------KAVSGSADGDVRTWA 98

Query: 2662 WNGKSSGIGDNPGGETATPRAILTGHDYEITCAAVCAEL 2700
             +     +             + TG D E+ C     E+
Sbjct: 97   LDTGQCLL------------TMTTGQDIEVYCVVYNQEV 17
>27465
          Length = 658

 Score = 35.8 bits (81), Expect = 0.25,   Method: Compositional matrix adjust.
 Identities = 27/111 (24%), Positives = 50/111 (45%)
 Frame = -1

Query: 2602 LVCGFWDKSFRVYSTDTGKLIQVVFGHWDVVTCLARSESYIGGNCYILSGSRDATLLLWY 2661
             + G +D++ +++ T + + +  + GH +VV  +A +  +  G+  +++GS D T  LW 
Sbjct: 316  FITGSYDRTCKIWDTASAEELHTLEGHRNVVYAIAFNNPF--GD-KVITGSFDKTCKLW- 149

Query: 2662 WNGKSSGIGDNPGGETATPRAILTGHDYEITCAAVCAELGLVLSGSQEGPC 2712
                     D     T      L GH  EI C +      L+ +GS +  C
Sbjct: 148  ------STADGKCYHT------LRGHTAEIVCVSFNPSSTLIATGSMDTTC 32
>04088
          Length = 511

 Score = 35.0 bits (79), Expect = 0.39,   Method: Compositional matrix adjust.
 Identities = 24/105 (22%), Positives = 47/105 (44%), Gaps = 4/105 (3%)
 Frame = +3

Query: 2608 DKSFRVYSTDTGKLIQVVFGH----WDVVTCLARSESYIGGNCYILSGSRDATLLLWYWN 2663
            D + R+   DTG+++    GH    + + +CL   ++ +      +SGS D  +  ++W+
Sbjct: 93   DNTVRLMDKDTGEMLNEFTGHKHSQYKIDSCLNNEDTLV------VSGSEDGKV--YFWD 248

Query: 2664 GKSSGIGDNPGGETATPRAILTGHDYEITCAAVCAELGLVLSGSQ 2708
               + + D    +T  P   L+ H  E+     CA+   +   SQ
Sbjct: 249  LVEAKLVDTLDHKTTRPVHSLSFHHAELCLMTACADKVFLWRSSQ 383
>02147
          Length = 1547

 Score = 32.7 bits (73), Expect = 1.9,   Method: Compositional matrix adjust.
 Identities = 24/64 (37%), Positives = 32/64 (50%), Gaps = 2/64 (3%)
 Frame = +2

Query: 2599 RYILVCGFWDKSFRVYSTD--TGKLIQVVFGHWDVVTCLARSESYIGGNCYILSGSRDAT 2656
            R+ +  G   + F++Y  D  TGK I+   GH+  V C+  S     G  Y  SGS D T
Sbjct: 707  RFFVAGG---EDFKMYKFDYETGKEIESFKGHFGPVHCVRFSPD---GELYA-SGSEDGT 865

Query: 2657 LLLW 2660
            L LW
Sbjct: 866  LRLW 877
>17598
          Length = 875

 Score = 32.3 bits (72), Expect = 2.7,   Method: Compositional matrix adjust.
 Identities = 44/212 (20%), Positives = 84/212 (39%), Gaps = 17/212 (8%)
 Frame = +1

Query: 2647 YILSGSRDATLLLWYWNGKSSGIGDNPGGETATPRAILTGHDYEITCAAVCAELGLVLSG 2706
            +++ G RD  L++W    +  G  D   G    PR  L GH + ++  ++ A+   VLS 
Sbjct: 7    FLIXGGRDKLLIVWDLVPRKDGDEDETWG---GPRRTLQGHSHFVSDVSLSADSRYVLSS 177

Query: 2707 SQEGPCLIHSMNGDLLRTLEGPENCLKPKLIQASREGHCVIFY----------ENGCFCT 2756
            S +            LR  +  +     + I  +R+   V F            +     
Sbjct: 178  SWDAT----------LRLWDIKKGNTTRRFISHTRDALAVAFSPDNRQIASGGRDKALKI 327

Query: 2757 FSVNGKLQATVETDDH---IRAIQLSRDGQ--YLLTGGDNGVVIV--RQVSDLKQLFAYP 2809
            ++  G+ + TV+ + H   +  ++  +D +   +++   +  + V   Q   LK  F   
Sbjct: 328  WNTVGECKFTVDANSHQDWVTCVKFHQDAKSPLVVSASMDKTIKVWDNQTMTLKHTFV-- 501

Query: 2810 GCDAGIRAMALSFDQRCIISGMASGSIVLFYN 2841
            G    I A+ L+     + SG   G IV+ +N
Sbjct: 502  GHKTQINAIDLALKTYYLASGSKDG-IVMTWN 594
>14859
          Length = 685

 Score = 31.6 bits (70), Expect = 4.7,   Method: Composition-based stats.
 Identities = 14/39 (35%), Positives = 26/39 (66%)
 Frame = -1

Query: 667 MKDSGVKEDELQAILNYLLTMHEDDNLMDVLQLLVALMA 705
           +KDSG++E EL     Y+  +HE ++L D+ Q+++  +A
Sbjct: 508 LKDSGIEESELT---EYISKLHEYNDLKDIAQMIIGNIA 401
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|22122399|ref|NP_666075.1| potassium
inwardly-rectifying channel J14 [Mus musculus]
         (434 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

07593                                                                 255   5e-86
29780                                                                  89   3e-18
19655                                                                  63   1e-15
>07593
          Length = 2271

 Score =  255 bits (652), Expect(2) = 5e-86,   Method: Compositional matrix adjust.
 Identities = 125/228 (54%), Positives = 166/228 (72%), Gaps = 2/228 (0%)
 Frame = -3

Query: 141  ETQTSIGYGVRSVTEECPAAVAAVVLQCIAGCVLDAFVVGAVMAKMAKPKKRNETLVFSE 200
            ETQ +IGYG R  TEECP A+  ++ Q   G +  A + G V AK+++PKKR ETL+FS+
Sbjct: 1054 ETQHTIGYGSRHTTEECPEAIVLMMFQSXFGVICQALMTGIVFAKLSRPKKRAETLMFSK 875

Query: 201  NAVVALRDHRLCLMWRVGNLRRSHLVEAHVRAQLLQPRVTPEGEYIPLDHQDVDVGFDGG 260
            +A +  +D  LCL+ RVG++R+S +VEAH+RA L++ ++T EG+ +PL   DVD+GFD G
Sbjct: 874  SACICKQDGDLCLLLRVGDMRKSQIVEAHIRAVLIKKKITKEGDVLPLYQFDVDLGFDEG 695

Query: 261  TDRIFLVSPITIVHEIDSASPLYELGRAELARADFELVVILEGMVEATAMTTQCRSSYLP 320
             DR+FLV P+ IVH+ID ASP +EL   +L R  FEL+V+LEG+VE+T MTTQ RSSYLP
Sbjct: 694  RDRLFLVWPVIIVHKIDEASPFWELTPEDLHREQFELIVVLEGIVESTGMTTQARSSYLP 515

Query: 321  GELLWGHRFEP-VLFQR-GSQYEVDYRHFHRTYEVPGTPVCSAKELDE 366
            GE+LWGHRFE  V FQ+   QY++D+  FH T  V  TP CSAKEL E
Sbjct: 514  GEVLWGHRFERLVTFQKENGQYQIDFSRFHNTIPV-DTPNCSAKELAE 374

 Score = 80.9 bits (198), Expect(2) = 5e-86,   Method: Compositional matrix adjust.
 Identities = 35/89 (39%), Positives = 53/89 (59%), Gaps = 2/89 (2%)
 Frame = -1

Query: 43   GSRRRGRFVKKDGHCNVRFVNLGGQGARYLSDLFTTCVDVRWRWMCLLFSCSFLASWLLF 102
              R R R V K+G  N+   N+  +  RYL+D+FTT VD++WR+  +LF+ +F+ SWL+F
Sbjct: 1353 SKRMRRRLVYKNGEVNITQTNIRKRRRRYLADIFTTLVDIKWRYNLMLFAMAFIVSWLIF 1174

Query: 103  GLTFWLIASLHGDLAAPPPP--APCFSQV 129
             L +WL+   HGDL         PC  ++
Sbjct: 1173 ALIWWLVCFSHGDLDNLKNSQWTPCVEEI 1087
>29780
          Length = 678

 Score = 89.4 bits (220), Expect = 3e-18,   Method: Compositional matrix adjust.
 Identities = 43/115 (37%), Positives = 69/115 (60%)
 Frame = +1

Query: 234 LLQPRVTPEGEYIPLDHQDVDVGFDGGTDRIFLVSPITIVHEIDSASPLYELGRAELARA 293
           +++   +PEG Y PL   +++   +G  D+I L+ PI + H I   SPLY++  A+L+  
Sbjct: 1   VIRKHSSPEGAYYPLYQTELEFEANGMGDKIILMWPIILTHRITPDSPLYDMRPADLSAQ 180

Query: 294 DFELVVILEGMVEATAMTTQCRSSYLPGELLWGHRFEPVLFQRGSQYEVDYRHFH 348
             E+++ L G VEAT    Q R+SY+P E+LWGHRFE     R  +Y++ +  +H
Sbjct: 181 KMEIILFLTGTVEATGEVCQARTSYVPREILWGHRFE-----RLEEYDISHGRWH 330
>19655
          Length = 855

 Score = 52.4 bits (124), Expect(2) = 1e-15,   Method: Compositional matrix adjust.
 Identities = 27/98 (27%), Positives = 44/98 (44%), Gaps = 2/98 (2%)
 Frame = +3

Query: 95  FLASWLLFGLTFWLIASLHGDL--AAPPPPAPCFSQVASXXXXXXXXXETQTSIGYGVRS 152
           FL  +L F   ++ +A LHGD      P   PC   +           ETQ++IGYG+  
Sbjct: 333 FLVFYLAFASVYYFLAWLHGDFDNLGNPNYIPCIENMEGAWDAFMFSIETQSTIGYGIIY 512

Query: 153 VTEECPAAVAAVVLQCIAGCVLDAFVVGAVMAKMAKPK 190
              EC + +  + LQ  AG + +  + G+ + +   P 
Sbjct: 513 AHPECGSTLPFIYLQIAAGFLFETLLFGSFLQRSQDPS 626

 Score = 48.1 bits (113), Expect(2) = 1e-15,   Method: Compositional matrix adjust.
 Identities = 19/48 (39%), Positives = 31/48 (64%)
 Frame = +2

Query: 50  FVKKDGHCNVRFVNLGGQGARYLSDLFTTCVDVRWRWMCLLFSCSFLA 97
            VKK+G  NV F  +  +  RYL DLF + ++++WR++ L F  +FL+
Sbjct: 197 LVKKEGQSNVAFKGVKSKTRRYLKDLFISFLEMKWRYVVLTFFTAFLS 340

 Score = 62.8 bits (151), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 33/88 (37%), Positives = 49/88 (55%)
 Frame = +2

Query: 179 VGAVMAKMAKPKKRNETLVFSENAVVALRDHRLCLMWRVGNLRRSHLVEAHVRAQLLQPR 238
           V  V AK+++PK R  TLVFS +A +   +  + L  RVG++RRSHL+E  V A L++  
Sbjct: 590 VWFVFAKISRPKHRRHTLVFSRHACILQEEGHMTLQIRVGDMRRSHLIETRVHALLVKRH 769

Query: 239 VTPEGEYIPLDHQDVDVGFDGGTDRIFL 266
           V  E    PL    ++       DR+F+
Sbjct: 770 VVKEKYVYPLYQHQIEFDAHEMGDRLFM 853
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|114326546|ref|NP_075907.2| phosphoglycerate mutase 1
[Mus musculus]
         (254 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

10738                                                                 312   7e-86
08759                                                                  28   2.4  
12443                                                                  28   2.6  
>10738
          Length = 1860

 Score =  312 bits (800), Expect = 7e-86,   Method: Compositional matrix adjust.
 Identities = 151/253 (59%), Positives = 188/253 (74%)
 Frame = -2

Query: 1    MAAYKLVLIRHGESAWNLENRFSGWYDADLSPAGHEEAKRGGQALRDAGYEFDICFTSVQ 60
            M  + L+L+RHGES WN +N F GW+DADLS AG  EAK   Q ++D GY +DI FTSV 
Sbjct: 1739 MGKHTLILVRHGESEWNKQNLFCGWHDADLSEAGXNEAKYAAQLIKDKGYLYDIAFTSVL 1560

Query: 61   KRAIRTLWTVLDAIDQMWLPVVRTWRLNERHYGGLTGLNKAETAAKHGEAQVKIWRRSYD 120
            KRAI+TL+ + D  D+ W+PV+R+WRLNERHYGGL GLNKAETAAKHGE QVKIWRRSYD
Sbjct: 1559 KRAIKTLYLIQDGTDRHWVPVLRSWRLNERHYGGLQGLNKAETAAKHGEDQVKIWRRSYD 1380

Query: 121  VXXXXXXXXXXFYSNISKDRRYADLTEDQLPSCESLKDTIARALPFWNEEIVPQIKEGKR 180
            V           +S    D +Y  L  + +P+CE LKDT+AR LP+W++ IVP++KEGK 
Sbjct: 1379 VPPPPLTPKDAEWS--GNDPKYTKLDPNVIPACECLKDTVARVLPYWSDAIVPELKEGKT 1206

Query: 181  VLIAAHGNSLRGIVKHLEGLSEEAIMELNLPTGIPIVYELDKNLKPIKPMQFLGDEETVR 240
            VLIAAHGNSLR +VK+L+ +++EAIM LN+PTGIP+VYELD+NLKPIK   +L  EE V+
Sbjct: 1205 VLIAAHGNSLRALVKYLDNMTDEAIMGLNIPTGIPLVYELDENLKPIKHF-YLASEEEVK 1029

Query: 241  KAMEAVAAQGKVK 253
             A   VA QGK K
Sbjct: 1028 AAEAKVANQGKAK 990
>08759
          Length = 2085

 Score = 28.5 bits (62), Expect = 2.4,   Method: Compositional matrix adjust.
 Identities = 20/55 (36%), Positives = 27/55 (49%), Gaps = 1/55 (1%)
 Frame = -2

Query: 21   RFSGWYDADL-SPAGHEEAKRGGQALRDAGYEFDICFTSVQKRAIRTLWTVLDAI 74
            R++  YD +L SPA  EE K        A YE+   +T V+K  I   W V D +
Sbjct: 1562 RYNQLYDQELHSPAVQEEEKANA-----ALYEYVANYTGVKKENISDEWMVSDTL 1413
>12443
          Length = 837

 Score = 28.5 bits (62), Expect = 2.6,   Method: Compositional matrix adjust.
 Identities = 18/71 (25%), Positives = 27/71 (38%), Gaps = 9/71 (12%)
 Frame = +2

Query: 46  RDAGYEFDICFTSVQK---------RAIRTLWTVLDAIDQMWLPVVRTWRLNERHYGGLT 96
           +D    F  CFTSV+K               W +  A  Q W  ++  W +    +G  T
Sbjct: 359 QDMIISF*CCFTSVKKLDLEENSLSEVFNLPWPIQMACLQTWSFIMCEWNIIAGQFGNST 538

Query: 97  GLNKAETAAKH 107
           GL     + +H
Sbjct: 539 GLAHTGLSHQH 571
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|219842353|ref|NP_694818.3| eukaryotic translation
initiation factor 2C, 2 [Mus musculus]
         (860 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

19404                                                                 315   7e-86
06972                                                                 275   5e-74
02516                                                                 124   2e-28
06326                                                                  66   7e-11
22922                                                                  51   2e-06
01764                                                                  44   2e-04
18928                                                                  30   5.7  
27677                                                                  29   6.3  
18700                                                                  29   7.0  
>19404
          Length = 576

 Score =  315 bits (806), Expect = 7e-86,   Method: Compositional matrix adjust.
 Identities = 155/192 (80%), Positives = 167/192 (86%), Gaps = 6/192 (3%)
 Frame = +1

Query: 526 KTPVYAEVKRVGDTVLGMATQCVQMKNVQRTTPQTLSNLCLKINVKLGGVNNILLPQGRP 585
           KTPVYAEVKRVGD + G+ATQCVQ KNV +TTPQTLSNLCLKINVKLGGVN+ILLP  RP
Sbjct: 1   KTPVYAEVKRVGDIMFGLATQCVQSKNVNKTTPQTLSNLCLKINVKLGGVNSILLPSIRP 180

Query: 586 PVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPNRYCATVRVQQHRQEIIQDLAA 645
            VF++PVIFLGADVTHPPAGD  KPSIAAVVGSMDAHP+RY A VRVQ+HRQE+I +LA 
Sbjct: 181 AVFREPVIFLGADVTHPPAGDSSKPSIAAVVGSMDAHPSRYAAAVRVQEHRQEVIYELAT 360

Query: 646 MVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFQ-----QVLHHELLAIREACIKLEKDYQ 700
           MVRELLIQFY+STRFKPTRIIFYRDGVSEGQF      QVL HEL AIREAC KLE DY+
Sbjct: 361 MVRELLIQFYRSTRFKPTRIIFYRDGVSEGQFHASTYLQVLSHELRAIREACTKLEGDYR 540

Query: 701 PG-ITFIVVQKR 711
           PG  TFIVVQKR
Sbjct: 541 PGNTTFIVVQKR 576
>06972
          Length = 1038

 Score =  275 bits (704), Expect = 5e-74,   Method: Compositional matrix adjust.
 Identities = 129/158 (81%), Positives = 136/158 (86%)
 Frame = +1

Query: 703 ITFIVVQKRHHTRLFCTDKNERVGKSGNIPAGTTVDTKITHPTEFDFYLCSHAGIQGTSR 762
           ITFIVVQKRHHTRLFC +K E+ GKSGNIPAGTTVD  ITHPTEFDFYLCSH GIQGT R
Sbjct: 4   ITFIVVQKRHHTRLFCAEKKEQSGKSGNIPAGTTVDVGITHPTEFDFYLCSHQGIQGTXR 183

Query: 763 PSHYHVLWDDNRFSSDELQILTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKE 822
           PSHYHVLWDDN F SDELQ LTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLV+KE
Sbjct: 184 PSHYHVLWDDNHFDSDELQCLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVEKE 363

Query: 823 HDSAEGSHTSGQSNGRDHQALAKAVQVHQDTLRTMYFA 860
           HDS EGSH SG S  R   A+A+A+ VH DT + MYFA
Sbjct: 364 HDSGEGSHQSGSSEDRTPGAMARAITVHADTKKVMYFA 477
>02516
          Length = 2764

 Score =  124 bits (311), Expect = 2e-28,   Method: Compositional matrix adjust.
 Identities = 110/405 (27%), Positives = 180/405 (44%), Gaps = 29/405 (7%)
 Frame = +1

Query: 437  DMRNKQFHTGIEIKVWAIACFAPQRQCTEVHLKSFTEQLRKISRDAGMPIQGQPCFCKYA 496
            DMR K+    + ++ W +     Q++ T+   K     L K+    GM I   P   +  
Sbjct: 1471 DMRGKKMVLAVPLQRWLLVV---QKRSTD-KAKDLAGILAKVGPPMGMNI-APPRMVQID 1635

Query: 497  QG-ADSVEPMFRHLKNTYAG-LQLVVVILPG-KTPVYAEVKRVGDTVLGMATQCVQ---M 550
            Q   DS     R  +N   G  QLVV +L   K   Y  +K+     + +A+Q V    +
Sbjct: 1636 QDRNDSYIHALR--ENIREGETQLVVCVLSNNKKDRYDAIKKYCCIDMPVASQMVTDKTL 1809

Query: 551  KNVQRTTPQTLSNLCLKINVKLGGVNNILLPQGRPPVFQQPVIFLGADVTHPPAGDGKKP 610
             N QR      + + +++N KLGGV  +       P+     + +G D  H  A  G+  
Sbjct: 1810 SNKQRLM-SVATKIAIQMNCKLGGVVWVC------PIPLVNTMIVGIDTYHDSAVRGQ-- 1962

Query: 611  SIAAVVGSMDAHPNRYCATVRVQQHRQEIIQDLAAMVRELLIQFYKSTRFK-PTRIIFYR 669
            S+  +V ++++  +RY +T   Q    E+   L   +   L  + +    K P +++ +R
Sbjct: 1963 SVGGIVATVNSDYSRYFSTCTFQMRHLELQDKLYFSIIACLKAYGRENNNKYPDKVVVFR 2142

Query: 670  DGVSEGQFQQVLHHELLAIREACIKLEK--DYQPGITFIVVQKRHHTRLF---------- 717
            DGV +GQ Q V  HE+  +R A  K  +  D    + +I+V+KR + R F          
Sbjct: 2143 DGVGDGQLQLVYEHEIPQVRRALNKCAERFDMTIKLAYIIVKKRTNARFFQEGVIMESGP 2322

Query: 718  ----------CTDKNERVGKSGNIPAGTTVDTKITHPTEFDFYLCSHAGIQGTSRPSHYH 767
                            +     N   GT +D   T PT FDF+L S +   GT  P+H++
Sbjct: 2323 GGARGGRGGGGGAGGGQRRGLTNPGPGTIIDNVATKPTWFDFFLISQSVRDGTVSPTHFN 2502

Query: 768  VLWDDNRFSSDELQILTYQLCHTYVRCTRSVSIPAPAYYAHLVAF 812
            V++D+    S+  Q + Y+LCH Y     ++ +PAP  YAH +AF
Sbjct: 2503 VIFDELDIKSEYYQRMAYKLCHMYYNWQGTIRVPAPCMYAHKLAF 2637
>06326
          Length = 486

 Score = 65.9 bits (159), Expect = 7e-11,   Method: Compositional matrix adjust.
 Identities = 46/148 (31%), Positives = 76/148 (51%), Gaps = 8/148 (5%)
 Frame = -3

Query: 583 GRPPVFQQPV---IFLGADVTHPPAGDGKKPSIAAVVGSMDAH-PNRYCATVRVQQHRQE 638
           G P + + PV   + +G DV H  +   K  S  A+V +MD     RY ++V      QE
Sbjct: 439 GAPWMIELPVRGLMTVGFDVCH--SSKDKNKSYGALVATMDLKLSTRYYSSVTEHMKGQE 266

Query: 639 IIQDLAAMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFQQVLHHELLAIREACIKL--- 695
           +   ++  +   L  + K     P RI+F+RDGV +GQ +QV++ E+  +++   ++   
Sbjct: 265 LSNQMSVNMTCALKAYRKHHGTLPERILFFRDGVGDGQLEQVVNTEVKYLKDQLDQIYKS 86

Query: 696 -EKDYQPGITFIVVQKRHHTRLFCTDKN 722
             KD    + FIVV KR +TR F  ++N
Sbjct: 85  AGKDVGCRMAFIVVSKRINTRYFARNRN 2
>22922
          Length = 970

 Score = 50.8 bits (120), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 33/107 (30%), Positives = 55/107 (51%), Gaps = 4/107 (3%)
 Frame = +3

Query: 583 GRPPVFQQPV---IFLGADVTHPPAGDGKKPSIAAVVGSMDAH-PNRYCATVRVQQHRQE 638
           G P + + PV   + +G DV H  +   K  S  A+V +MD     RY ++V      QE
Sbjct: 48  GAPWMIELPVRGLMTVGFDVCH--SSKDKNKSYGAIVATMDLKLSTRYYSSVTEHMKGQE 221

Query: 639 IIQDLAAMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFQQVLHHEL 685
           +   ++  +   L  + ++    P RI+F+RDGV +GQ  QV++ E+
Sbjct: 222 LSNQMSVNMTCALKAYRENHGSLPERILFFRDGVGDGQLAQVVNTEV 362

 Score = 46.6 bits (109), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 20/55 (36%), Positives = 35/55 (63%)
 Frame = +2

Query: 758 QGTSRPSHYHVLWDDNRFSSDELQILTYQLCHTYVRCTRSVSIPAPAYYAHLVAF 812
           +GT  P+ Y+V+ D+    +D+LQ+L+Y++ H Y   + +  +PA   YAH +AF
Sbjct: 569 KGTVSPTSYNVIQDNMGLDADKLQMLSYKMTHLYYNWSGTCRVPAVCQYAHKLAF 733
>01764
          Length = 441

 Score = 44.3 bits (103), Expect = 2e-04,   Method: Composition-based stats.
 Identities = 18/56 (32%), Positives = 31/56 (55%)
 Frame = -3

Query: 757 IQGTSRPSHYHVLWDDNRFSSDELQILTYQLCHTYVRCTRSVSIPAPAYYAHLVAF 812
           +     P  ++V++D+    S+  Q + Y+LCH Y     ++ +PAP  YAH +AF
Sbjct: 292 VTAQCHPLTFNVIFDELDIKSEYYQRMAYKLCHMYYNWQGTIRVPAPCMYAHKLAF 125

 Score = 30.8 bits (68), Expect = 2.5,   Method: Composition-based stats.
 Identities = 10/23 (43%), Positives = 16/23 (69%)
 Frame = -1

Query: 662 PTRIIFYRDGVSEGQFQQVLHHE 684
           P +++ +RDGV +GQ Q V  H+
Sbjct: 441 PDKVVVFRDGVGDGQLQLVYEHD 373
>18928
          Length = 955

 Score = 29.6 bits (65), Expect = 5.7,   Method: Compositional matrix adjust.
 Identities = 21/73 (28%), Positives = 35/73 (47%), Gaps = 5/73 (6%)
 Frame = +1

Query: 68  PRRVNREIVEHMVQHFKTQIFGDRKPVFDGRKNLYTAMPLPIGRDKVELEVTLPGEGKDR 127
           P+ V+ ++  H V + K+ ++     V  G+    T +PLP+G D+VE       +  DR
Sbjct: 364 PKVVSEDVKRH-VHNLKSNVY-----VVSGQAKGKTLLPLPVGTDRVETMEEEENDTYDR 525

Query: 128 -----IFKVSIKW 135
                I  V I+W
Sbjct: 526 NLVHAIETVIIEW 564
>27677
          Length = 632

 Score = 29.3 bits (64), Expect = 6.3,   Method: Composition-based stats.
 Identities = 12/43 (27%), Positives = 23/43 (53%)
 Frame = +1

Query: 452 WAIACFAPQRQCTEVHLKSFTEQLRKISRDAGMPIQGQPCFCK 494
           WAI    P R  + +HL++    + +++  +G  +  QPCF +
Sbjct: 205 WAITAELP-RSSSPIHLRAALSYMSRVATVSGSTLTRQPCFSR 330
>18700
          Length = 1224

 Score = 29.3 bits (64), Expect = 7.0,   Method: Compositional matrix adjust.
 Identities = 16/56 (28%), Positives = 24/56 (42%)
 Frame = -2

Query: 718 CTDKNERVGKSGNIPAGTTVDTKITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDN 773
           C  + +R G + +      V   +  P   D  +C H G+Q TS+P H      DN
Sbjct: 866 CKREEKRRGGTRSSAYLVAVFGTLCKPPRIDCAVCIHNGVQPTSQPQHTENFRLDN 699
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31982726|ref|NP_058075.2| serine/arginine-rich
protein specific kinase 1 [Mus musculus]
         (648 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

01106                                                                 314   7e-86
21800                                                                 201   1e-82
16350                                                                 187   7e-70
20513                                                                 105   5e-23
11404                                                                  80   3e-15
36481                                                                  76   4e-14
14126                                                                  67   2e-11
28638                                                                  55   8e-11
29360                                                                  62   6e-10
18401                                                                  62   1e-09
01707                                                                  60   3e-09
01756                                                                  57   3e-08
32000                                                                  52   6e-07
13078                                                                  52   9e-07
29581                                                                  51   1e-06
19761                                                                  42   5e-04
01966                                                                  41   0.002
01060                                                                  40   0.002
26009                                                                  40   0.003
17975                                                                  40   0.003
03240                                                                  39   0.007
00300                                                                  39   0.008
04591                                                                  38   0.016
19301                                                                  38   0.016
31885                                                                  37   0.017
18921                                                                  37   0.027
13592                                                                  37   0.027
21079                                                                  37   0.035
18481                                                                  35   0.080
02638                                                                  35   0.12 
31489                                                                  35   0.12 
01392                                                                  35   0.13 
23319                                                                  34   0.18 
14420                                                                  34   0.19 
15910                                                                  33   0.25 
00392                                                                  33   0.27 
19094                                                                  33   0.33 
20152                                                                  33   0.50 
06405                                                                  33   0.50 
00715                                                                  32   0.84 
26711                                                                  32   0.93 
17637                                                                  32   1.1  
06419                                                                  31   1.4  
13212                                                                  31   1.6  
32357                                                                  31   1.8  
27405                                                                  31   1.9  
14477                                                                  30   2.3  
26052                                                                  30   2.3  
26560                                                                  30   2.4  
25725                                                                  30   2.9  
12786                                                                  30   3.4  
03508                                                                  30   3.8  
25951                                                                  30   4.1  
27546                                                                  30   4.2  
27274                                                                  29   4.8  
21433                                                                  29   4.8  
12721                                                                  29   4.8  
18484                                                                  29   5.0  
30755                                                                  29   5.7  
36002                                                                  28   7.7  
>01106
          Length = 878

 Score =  314 bits (805), Expect = 7e-86,   Method: Compositional matrix adjust.
 Identities = 148/193 (76%), Positives = 167/193 (86%)
 Frame = +3

Query: 48  ILGSDDDEQEDPNDYCKGGYHLVKIGDLFNGRYHVIRKLGWGHFSTVWLSWDIQGKKFVA 107
           ILGSDDDEQEDP DYCKGGYH VK GDLFNGRYHVIRKLGWGHFSTVWL WD+  K+FVA
Sbjct: 228 ILGSDDDEQEDPRDYCKGGYHPVKNGDLFNGRYHVIRKLGWGHFSTVWLCWDLTCKRFVA 407

Query: 108 MKVVKSAEHYTETALDEIRLLKSVRNSDPNDPNGEMVVQLLDDFKISGVNGTHICMVFEV 167
           +KVVKSA+HYTETALDE++LLK VR SD  DP     VQLLDDFKISGVNGTH+ MVFEV
Sbjct: 408 LKVVKSAQHYTETALDEVKLLKCVRESDVADPARAKCVQLLDDFKISGVNGTHVAMVFEV 587

Query: 168 LGHHLLKWIIKSNYQGLPLPCVKKIIQQVLQGLDYLHTKCRIIHTDIKPENILLSVNEQY 227
           LG++LLK II+SNYQG+P+  VK II+QVL+GL Y+H KCRIIHTDIKPENIL+ V+E Y
Sbjct: 588 LGYNLLKLIIRSNYQGIPIHNVKLIIRQVLEGLSYMHAKCRIIHTDIKPENILICVDETY 767

Query: 228 IRRLAAEATEWQR 240
           IR+LAA+A E QR
Sbjct: 768 IRKLAADAFESQR 806
>21800
          Length = 855

 Score =  201 bits (512), Expect(2) = 1e-82,   Method: Compositional matrix adjust.
 Identities = 95/128 (74%), Positives = 111/128 (86%)
 Frame = +2

Query: 113 SAEHYTETALDEIRLLKSVRNSDPNDPNGEMVVQLLDDFKISGVNGTHICMVFEVLGHHL 172
           SA+HYTETALDEI+LLK VRNSD  DP  E  VQLLDDFKISGVNGTH+CMVFEVLG++L
Sbjct: 410 SAQHYTETALDEIKLLKCVRNSDETDPAREKSVQLLDDFKISGVNGTHVCMVFEVLGYNL 589

Query: 173 LKWIIKSNYQGLPLPCVKKIIQQVLQGLDYLHTKCRIIHTDIKPENILLSVNEQYIRRLA 232
           LK II+SNYQG+P+  VK II+QVL+GL+YLH KC IIHTDIKPENIL+ V++ YIR+LA
Sbjct: 590 LKLIIRSNYQGIPVHNVKLIIRQVLEGLNYLHAKCNIIHTDIKPENILICVDDNYIRKLA 769

Query: 233 AEATEWQR 240
            +A EWQR
Sbjct: 770 VDAFEWQR 793

 Score =  124 bits (311), Expect(2) = 1e-82,   Method: Compositional matrix adjust.
 Identities = 54/65 (83%), Positives = 59/65 (90%)
 Frame = +3

Query: 48  ILGSDDDEQEDPNDYCKGGYHLVKIGDLFNGRYHVIRKLGWGHFSTVWLSWDIQGKKFVA 107
           ILGSDDDEQEDP DYCKGGYH VK GDLF+GRYHV+RKLGWGHFSTVWL WD+  K+FVA
Sbjct: 216 ILGSDDDEQEDPRDYCKGGYHPVKNGDLFHGRYHVVRKLGWGHFSTVWLCWDLNCKRFVA 395

Query: 108 MKVVK 112
           +KVVK
Sbjct: 396 LKVVK 410
>16350
          Length = 1108

 Score =  187 bits (476), Expect(2) = 7e-70,   Method: Compositional matrix adjust.
 Identities = 81/102 (79%), Positives = 93/102 (91%)
 Frame = +2

Query: 486 VKIADLGNACWVHKHFTEDIQTRQYRSLEVLIGSGYNTPADIWSTACMAFELATGDYLFE 545
           VKIADLGNACW + HFTEDIQTRQYR LEVLIG+GY TPADIWSTACMAFELATGDYLFE
Sbjct: 356 VKIADLGNACWTYHHFTEDIQTRQYRCLEVLIGAGYGTPADIWSTACMAFELATGDYLFE 535

Query: 546 PHSGEDYTRDEDHIALIIELLGKVPRKLIVAGKYSKEFFTKK 587
           PHSGEDY+RDEDH+A +IEL+G +PR + ++GKYS+EFF +K
Sbjct: 536 PHSGEDYSRDEDHLAHVIELVGPIPRHIALSGKYSREFFNRK 661

 Score = 95.5 bits (236), Expect(2) = 7e-70,   Method: Compositional matrix adjust.
 Identities = 43/61 (70%), Positives = 51/61 (83%)
 Frame = +3

Query: 587 KGDLKHITKLKPWGLLEVLVEKYEWPQEEAAGFTDFLLPMLELMPEKRATAAECLRHPWL 646
           KG+L+HITKLKPWGL+EVLVEKYEW  ++A  F DFL PMLE  PE+RATAA+ L+HPWL
Sbjct: 660 KGELRHITKLKPWGLVEVLVEKYEWDPKDAKAFADFLAPMLEFDPEQRATAAQSLQHPWL 839

Query: 647 N 647
            
Sbjct: 840 K 842
>20513
          Length = 405

 Score =  105 bits (263), Expect = 5e-23,   Method: Compositional matrix adjust.
 Identities = 47/68 (69%), Positives = 57/68 (83%)
 Frame = -1

Query: 580 SKEFFTKKGDLKHITKLKPWGLLEVLVEKYEWPQEEAAGFTDFLLPMLELMPEKRATAAE 639
           S+EFF +KG+L+HITKLKPWGL+EVLVEKYEW  ++A  F DFL PMLE  PE+RATAA+
Sbjct: 405 SREFFNRKGELRHITKLKPWGLVEVLVEKYEWDPKDAKAFADFLAPMLEFDPEQRATAAQ 226

Query: 640 CLRHPWLN 647
            L+HPWL 
Sbjct: 225 SLQHPWLK 202
>11404
          Length = 563

 Score = 79.7 bits (195), Expect = 3e-15,   Method: Compositional matrix adjust.
 Identities = 48/155 (30%), Positives = 87/155 (56%), Gaps = 1/155 (0%)
 Frame = +1

Query: 68  HLVKIGDLFNGRYHVIRKLGWGHFSTVWLSWDIQGKKFVAMKVVKSAEHYTETALDEIRL 127
           +++  G+ +  RY +   +G G F  V  ++D    + VA+K++K+ + +   A  E++L
Sbjct: 109 YIISPGEKWADRYEIDSLIGKGSFGQVVKAYDHTDNEQVAIKIIKNKKPFLNQAQIEVKL 288

Query: 128 LKSVRNSDPNDPNGEMVVQLLDDFKISGVNGTHICMVFEVLGHHLLKWIIKSNYQGLPLP 187
           L+ +   D +  N   +V+L   F       +H+C+VFE+L ++L   +  +N++G+ L 
Sbjct: 289 LEMMNRHDTD--NKYYIVRLKRHFMFR----SHLCLVFELLSYNLYDLLRNTNFRGVSLN 450

Query: 188 CVKKIIQQVLQGLDYLHT-KCRIIHTDIKPENILL 221
             +K  QQ+   L +L T +  IIH D+KPENILL
Sbjct: 451 LTRKFAQQLCTALLFLATPEMSIIHCDLKPENILL 555
>36481
          Length = 806

 Score = 76.3 bits (186), Expect = 4e-14,   Method: Compositional matrix adjust.
 Identities = 48/141 (34%), Positives = 79/141 (56%)
 Frame = +2

Query: 87  GWGHFSTVWLSWDIQGKKFVAMKVVKSAEHYTETALDEIRLLKSVRNSDPNDPNGEMVVQ 146
           G G F  V    D+     +A+K++K+ + Y E A  EI +L+ +R  DP+  +  M VQ
Sbjct: 389 GEGTFGKVVQCKDLLKGDDIALKIIKNVDKYREAAKLEINVLEKLREKDPHAKH--MCVQ 562

Query: 147 LLDDFKISGVNGTHICMVFEVLGHHLLKWIIKSNYQGLPLPCVKKIIQQVLQGLDYLHTK 206
           +LD F   G    H+C+ F +LG  +  ++  ++Y   P+  V+ I  Q+   +++LH  
Sbjct: 563 MLDWFDYHG----HVCISFHMLGLSVFDFLKDNSYGAYPIEQVRHISYQLCYAVNFLHEN 730

Query: 207 CRIIHTDIKPENILLSVNEQY 227
            ++ HTD+KPENIL  V+ QY
Sbjct: 731 -QLTHTDLKPENILF-VDSQY 787
>14126
          Length = 1265

 Score = 67.0 bits (162), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 48/149 (32%), Positives = 85/149 (57%), Gaps = 5/149 (3%)
 Frame = +3

Query: 79  RYHVIRKLGWGHFSTVWLSWDIQGK-KFVAMKVVK---SAEHYTETALDEIRLLKSVRNS 134
           +Y  +  +G G + TV+ + D++ + +FVAMK ++   + E     A+ EI +LK +   
Sbjct: 192 KYEEVAVIGNGAYGTVYKARDLRNQGEFVAMKRIRLNNTEEGMPMMAIREISMLKQLEQY 371

Query: 135 DPNDPNGEMVVQLLDDFKISGVNG-THICMVFEVLGHHLLKWIIKSNYQGLPLPCVKKII 193
           +   PN   VV+LLD    +  +    + +VFE + H L  ++ K    GL    +K ++
Sbjct: 372 E--HPN---VVRLLDVSHNTITDREIRLNLVFEYIEHDLATYLAKCPSPGLGPDRIKDLM 536

Query: 194 QQVLQGLDYLHTKCRIIHTDIKPENILLS 222
            Q+L G+D+LH+  RI+H D+KP+N+L+S
Sbjct: 537 LQLLNGVDFLHSN-RIVHRDLKPQNLLIS 620

 Score = 53.9 bits (128), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 52/176 (29%), Positives = 81/176 (46%), Gaps = 5/176 (2%)
 Frame = +3

Query: 476 LEPKN---AEKLQVKIADLGNA--CWVHKHFTEDIQTRQYRSLEVLIGSGYNTPADIWST 530
           L+P+N   ++  ++K+AD G A     H   T  + T  YRS EVL+ + Y T  DIWS 
Sbjct: 594 LKPQNLLISKDGRLKLADFGLARIYSFHMALTTVVVTLWYRSPEVLMQAEYGTSVDIWSC 773

Query: 531 ACMAFELATGDYLFEPHSGEDYTRDEDHIALIIELLGKVPRKLIVAGKYSKEFFTKKGDL 590
            C+  EL T   LF+  S      + D +  I E++G  P     AG + +     +   
Sbjct: 774 GCIFAELFTRRALFKGSS------EFDQLKKIFEVIGLPP-----AGDWPEGVSVHRNSF 920

Query: 591 KHITKLKPWGLLEVLVEKYEWPQEEAAGFTDFLLPMLELMPEKRATAAECLRHPWL 646
           +      P   L+ LV + + PQ +     D +  ML     +R ++ E L HP+L
Sbjct: 921 RP----TPPVPLQTLVPEMD-PQAK-----DLMEKMLVFKSGRRISSRESLLHPYL 1058
>28638
          Length = 1458

 Score = 50.4 bits (119), Expect(2) = 8e-11,   Method: Compositional matrix adjust.
 Identities = 30/116 (25%), Positives = 63/116 (54%)
 Frame = -3

Query: 68   HLVKIGDLFNGRYHVIRKLGWGHFSTVWLSWDIQGKKFVAMKVVKSAEHYTETALDEIRL 127
            +++  G+ +  RY +   +G G F  V  ++D   ++ VA+K++K+ + +   A  E++L
Sbjct: 1177 YIINPGEKWLDRYEIDSLIGKGSFGQVVKAYDHGDQEQVAIKIIKNKKPFLNQAQIEVKL 998

Query: 128  LKSVRNSDPNDPNGEMVVQLLDDFKISGVNGTHICMVFEVLGHHLLKWIIKSNYQG 183
            L+ +   D +  N   +V+L   F        H+C+VFE+L ++L   +  +N++G
Sbjct: 997  LELMNRHDAD--NXYYIVRLKRHFMFR----NHLCLVFELLSYNLYDLLRNTNFRG 848

 Score = 34.7 bits (78), Expect(2) = 8e-11,   Method: Compositional matrix adjust.
 Identities = 19/42 (45%), Positives = 26/42 (61%), Gaps = 1/42 (2%)
 Frame = -1

Query: 182 QGLPLPCVKKIIQQVLQGLDYLHT-KCRIIHTDIKPENILLS 222
           +G+ L   +K  QQ+   L +L T +  IIH D+KPENILL 
Sbjct: 852 EGVSLNLTRKFAQQLCTALLFLATPEMNIIHCDLKPENILLC 727

 Score = 55.1 bits (131), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 24/62 (38%), Positives = 39/62 (62%)
 Frame = -1

Query: 480 NAEKLQVKIADLGNACWVHKHFTEDIQTRQYRSLEVLIGSGYNTPADIWSTACMAFELAT 539
           N ++  +KI D G++C + +   + IQ+R YRS EVL+G  Y+   D+WS  C+  E+ T
Sbjct: 726 NPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGVPYDLAIDMWSLGCILVEMHT 547

Query: 540 GD 541
           G+
Sbjct: 546 GE 541
>29360
          Length = 363

 Score = 62.4 bits (150), Expect = 6e-10,   Method: Compositional matrix adjust.
 Identities = 39/125 (31%), Positives = 67/125 (53%)
 Frame = +3

Query: 97  SWDIQGKKFVAMKVVKSAEHYTETALDEIRLLKSVRNSDPNDPNGEMVVQLLDDFKISGV 156
            W     + VA+K++K+   Y      E+ +L+ +     +D N    V+  + F+    
Sbjct: 9   CWKKGTSEIVAIKILKNHPSYARQGQIEVSILQRLSQESADDYN---FVRAFECFQ---- 167

Query: 157 NGTHICMVFEVLGHHLLKWIIKSNYQGLPLPCVKKIIQQVLQGLDYLHTKCRIIHTDIKP 216
           +  H C+VFE+L  +L  ++ ++ +Q LPL  ++ I QQVL  L  L  +  +IH D+KP
Sbjct: 168 HKNHTCLVFEMLEQNLYDFLKQNKFQPLPLKYIRPITQQVLTALRKL-KQLGLIHADLKP 344

Query: 217 ENILL 221
           ENI+L
Sbjct: 345 ENIML 359
>18401
          Length = 463

 Score = 61.6 bits (148), Expect = 1e-09,   Method: Composition-based stats.
 Identities = 39/151 (25%), Positives = 74/151 (49%), Gaps = 8/151 (5%)
 Frame = -3

Query: 505 IQTRQYRSLEVLIGSGYNTPADIWSTACMAFELATGDYLFEPHSGEDYTRDEDHIALIIE 564
           + TR YR+ EV++  G++ P D+WS  C+ FEL TG  LF+ H       +++H+A++  
Sbjct: 449 VSTRHYRAPEVILELGWSHPCDVWSVGCIMFELYTGYTLFQTHD------NKEHLAMMER 288

Query: 565 LLGKVPRKLIVAGKYSKEFFTKKGDLKHITKL--------KPWGLLEVLVEKYEWPQEEA 616
           +LG +P ++    K  K F   + D+   + +        KP  LL  + ++     ++ 
Sbjct: 287 ILGSLPYRMAKKTKKQKYFHHGRLDVPERSSMARYVRENTKP--LLRYVKDRENKDHQQ- 117

Query: 617 AGFTDFLLPMLELMPEKRATAAECLRHPWLN 647
               D +  +L      R +  + L+HP+ +
Sbjct: 116 --LFDLMKKLLAYEASSRYSLLQALQHPFFS 30
>01707
          Length = 757

 Score = 60.1 bits (144), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 46/147 (31%), Positives = 81/147 (55%), Gaps = 3/147 (2%)
 Frame = +1

Query: 79  RYHVIRKLGWGHFSTVWLSWDIQGKKFVAMKVVKSAEH---YTETALDEIRLLKSVRNSD 135
           +Y  I K+G G +  V+   + +  + VA+K    +E      + A+ EIR+LK +++  
Sbjct: 67  KYEKIGKIGEGSYGVVFKCRNKETSQLVAIKKFVESEDDPLIKKIAMREIRMLKQLKH-- 240

Query: 136 PNDPNGEMVVQLLDDFKISGVNGTHICMVFEVLGHHLLKWIIKSNYQGLPLPCVKKIIQQ 195
              PN   +V+L++ F+        + +VF+ + H LL  + +   +GLP P VK+II Q
Sbjct: 241 ---PN---LVRLIEVFR----RKKRLHLVFDYVDHTLLNELDRYP-RGLPEPMVKRIIYQ 387

Query: 196 VLQGLDYLHTKCRIIHTDIKPENILLS 222
            L  +++ H +   IH D+KPENIL++
Sbjct: 388 TLLAVNFCH-QYNTIHRDVKPENILIT 465

 Score = 49.7 bits (117), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 33/94 (35%), Positives = 50/94 (53%), Gaps = 5/94 (5%)
 Frame = +1

Query: 485 QVKIADLGNACWVH---KHFTEDIQTRQYRSLEVLIG-SGYNTPADIWSTACMAFELATG 540
           QVK+ D G A  +      +T+ + TR YR+ E+L+G + Y  P D+W+  C+  EL TG
Sbjct: 475 QVKLCDFGFARILTGPGDEYTDYVATRWYRAPELLVGDTQYGPPVDVWAIGCVFAELLTG 654

Query: 541 DYLFEPHSGEDYTRDEDHIALIIELLGK-VPRKL 573
             L+   S      D D + LI + LG  +PR +
Sbjct: 655 QALWPGRS------DVDQLHLIRKTLGDLIPRHI 738
>01756
          Length = 1858

 Score = 57.0 bits (136), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 49/163 (30%), Positives = 87/163 (53%), Gaps = 7/163 (4%)
 Frame = -3

Query: 77   NGRYHVIRKLGWGHFSTVWLSWDIQGKKFVAMKVV---KSAEHYTETALDEIRLLKSVRN 133
            + +Y  + K+G G F  V+ +   + K+ VAMK V      E +  TAL EI++L+ +  
Sbjct: 1745 DAKYEKLAKIGQGTFGEVFKARCKKTKQVVAMKKVLMDNEKEGFPITALREIKILQLL-- 1572

Query: 134  SDPNDPNGEMVVQLLD--DFKISGVN--GTHICMVFEVLGHHLLKWIIKSNYQGLPLPCV 189
                  N E VV L++    K +  N   +   +VFE   H  L  ++ +      LP +
Sbjct: 1571 ------NHENVVDLIEICSTKATSANRYKSMFYLVFEFCEHD-LAGLLSNMSVVFNLPEI 1413

Query: 190  KKIIQQVLQGLDYLHTKCRIIHTDIKPENILLSVNEQYIRRLA 232
            K++++Q++ GL Y+H + +I+H D+K  NIL++  +Q + +LA
Sbjct: 1412 KEVMKQLMNGLYYIH-RNKILHRDMKAANILIT--KQGVLKLA 1293
>32000
          Length = 644

 Score = 52.4 bits (124), Expect = 6e-07,   Method: Composition-based stats.
 Identities = 50/167 (29%), Positives = 72/167 (43%), Gaps = 4/167 (2%)
 Frame = -1

Query: 485 QVKIADLGNACWVH---KHFTEDIQTRQYRSLEVLIGSG-YNTPADIWSTACMAFELATG 540
           ++KIAD G A       + +T ++ T  YR+ E+L+G   Y+ P DIWS  C+  E+ T 
Sbjct: 575 KMKIADFGLARVFGLPVRTYTHEVITLWYRAPEILLGCRFYSVPVDIWSLGCIFVEMMTR 396

Query: 541 DYLFEPHSGEDYTRDEDHIALIIELLGKVPRKLIVAGKYSKEFFTKKGDLKHITKLKPWG 600
             LF   S      + D +  I   LG  P + +  G       +K  D K      P  
Sbjct: 395 RALFPGDS------EIDQLYRIFRTLG-TPDEKVWPG------VSKLPDYKPTFPKWPLK 255

Query: 601 LLEVLVEKYEWPQEEAAGFTDFLLPMLELMPEKRATAAECLRHPWLN 647
            LE +V           G  D L  ML   P +R +A   +RHP+ N
Sbjct: 254 NLETVVSL------SKVGL-DLLKRMLTYNPNRRISARSAMRHPYFN 135
>13078
          Length = 773

 Score = 51.6 bits (122), Expect = 9e-07,   Method: Compositional matrix adjust.
 Identities = 23/70 (32%), Positives = 40/70 (57%)
 Frame = -1

Query: 520 GYNTPADIWSTACMAFELATGDYLFEPHSGEDYTRDEDHIALIIELLGKVPRKLIVAGKY 579
           G++ P D+WS  C+ FEL TG  LF+ H       +++H+A++  +LG +P ++    K 
Sbjct: 749 GWSQPCDVWSIGCIMFELYTGYTLFQTHD------NKEHLAMMERILGSLPYRMAKKTKK 588

Query: 580 SKEFFTKKGD 589
            K F+  + D
Sbjct: 587 QKYFYHGRLD 558
>29581
          Length = 1278

 Score = 51.2 bits (121), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 53/166 (31%), Positives = 71/166 (42%), Gaps = 5/166 (3%)
 Frame = -2

Query: 486 VKIADLG---NACWVHKHFTEDIQTRQYRSLEVLIGS-GYNTPADIWSTACMAFELATGD 541
           VKIAD G   N     K  T  + T  YR+ E+L GS  ++T  D+WS  C+  EL    
Sbjct: 932 VKIADFGLARNYGKPQKPMTPKVVTLWYRAPELLFGSKTHSTAIDMWSAGCILGELLGHK 753

Query: 542 YLFEPHSGEDYTRDEDHIALIIELLGKVPRKLIVAGKYSKEFFTKKGDLKHIT-KLKPWG 600
            L    S      D   I LI+ELLG  P   I  G      F++    +  T K +P+ 
Sbjct: 752 PLMPGRS------DLQQIELIMELLG-TPNDTIWPG------FSQLPAFEQFTLKKQPYN 612

Query: 601 LLEVLVEKYEWPQEEAAGFTDFLLPMLELMPEKRATAAECLRHPWL 646
            L      + W  E      + L       P+KRATA +CL H + 
Sbjct: 611 NLR---HTFPWLSESGIRLLNGLF---MYHPQKRATAEDCLEHSYF 492
>19761
          Length = 473

 Score = 42.4 bits (98), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 33/114 (28%), Positives = 58/114 (50%), Gaps = 6/114 (5%)
 Frame = -3

Query: 476 LEPKN---AEKLQVKIADLGNACWV---HKHFTEDIQTRQYRSLEVLIGSGYNTPADIWS 529
           L+P+N    EK  V++ DLG A  +       T  + T  Y S E+L    YN+ +DIWS
Sbjct: 339 LKPQNIYVTEKGDVRLGDLGLARKLTGPADFATSQVGTIMYLSPEILSQQPYNSKSDIWS 160

Query: 530 TACMAFELATGDYLFEPHSGEDYTRDEDHIALIIELLGKVPRKLIVAGKYSKEF 583
             C+ +++          +G+  + +   + L+++++G   RKL +   YS+EF
Sbjct: 159 LGCVFYDI----------TGKKGSDEMGVMFLLVQVMGG--RKLPLPDHYSQEF 34

 Score = 30.8 bits (68), Expect = 1.7,   Method: Compositional matrix adjust.
 Identities = 15/41 (36%), Positives = 24/41 (58%), Gaps = 1/41 (2%)
 Frame = -3

Query: 183 GLPLPCVKKIIQQVLQGLDYLHTKCRII-HTDIKPENILLS 222
           GLP   +   + Q    L+Y+HT   +I H D+KP+NI ++
Sbjct: 435 GLPERLIVCWLMQTASALNYMHTHTPVILHRDLKPQNIYVT 313
>01966
          Length = 1735

 Score = 40.8 bits (94), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 42/151 (27%), Positives = 78/151 (51%), Gaps = 5/151 (3%)
 Frame = -1

Query: 77   NGRYHVIRKLGWGHFSTVWLSWDIQGKKFVAMKVVK---SAEHYTETALDEIRLLKSVRN 133
            N R +V R L   H +T        G+K +AMK ++   S +    +A+ EI +L+ +R+
Sbjct: 1687 NRRRNVRRGL*CRHRAT--------GRK-LAMKKIRLRGSEDGVPSSAIREIAMLRELRH 1535

Query: 134  SDPNDPNGEMVVQLLDDFKISGVNGTHICMVFEVLGHHLLKWIIKSNYQGLPL--PCVKK 191
            ++         +  L+D  +       + +VFE L   L  +I K   +G+ L    VK 
Sbjct: 1534 TN---------IVCLEDVIM---EDERLFLVFEFLSMDLKMYIDKFP-EGVVLDRRLVKS 1394

Query: 192  IIQQVLQGLDYLHTKCRIIHTDIKPENILLS 222
             + Q++ G+++ H + RI+H D+KP+N+L++
Sbjct: 1393 YVFQIVTGINFCHQR-RIVHRDLKPQNLLIN 1304
>01060
          Length = 1800

 Score = 40.4 bits (93), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 37/145 (25%), Positives = 73/145 (50%), Gaps = 5/145 (3%)
 Frame = +1

Query: 83  IRKLGWGHFSTVWLSWDIQGKKFVAMKVVK---SAEHYTETALDEIRLLKSVRNSDPNDP 139
            +K+G G +  V+        + +AMK ++   S +    +A+ EI +L+ +R+++    
Sbjct: 88  FQKIGEGTYGVVYKCRHRATGRKLAMKKIRLRGSEDGVPSSAIREIAMLRELRHTN---- 255

Query: 140 NGEMVVQLLDDFKISGVNGTHICMVFEVLGHHLLKWIIKSNYQGLPLP--CVKKIIQQVL 197
                +  L+D  +       + +VFE L   L K  I    +G+ L    VK  + Q++
Sbjct: 256 -----IVCLEDVIM---EDERLFLVFEFLSMDL-KMYIDKFPEGVVLDRRLVKSYVFQIV 408

Query: 198 QGLDYLHTKCRIIHTDIKPENILLS 222
            G+ + H + RI+H D+KP+N+L++
Sbjct: 409 TGIXFCHQR-RIVHRDLKPQNLLIN 480

 Score = 39.3 bits (90), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 23/70 (32%), Positives = 38/70 (54%), Gaps = 4/70 (5%)
 Frame = +1

Query: 486 VKIADLGNA---CWVHKHFTEDIQTRQYRSLEVLIG-SGYNTPADIWSTACMAFELATGD 541
           +KIAD G A       + +T ++ T  YR+ E+L+G S Y+TP D+WS   +  ++    
Sbjct: 493 IKIADFGMARTFALPVRAYTHEVVTLWYRAPEILMGASKYSTPVDVWSIGTIFADMLIRT 672

Query: 542 YLFEPHSGED 551
            +F+  S  D
Sbjct: 673 PIFKGDSEID 702
>26009
          Length = 886

 Score = 40.0 bits (92), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 14/33 (42%), Positives = 27/33 (81%)
 Frame = +3

Query: 189 VKKIIQQVLQGLDYLHTKCRIIHTDIKPENILL 221
            K +++Q++  LD++H+K +++H DIKPEN+L+
Sbjct: 717 AKSVMKQLVSALDFMHSK-QLVHRDIKPENVLI 812
>17975
          Length = 449

 Score = 40.0 bits (92), Expect = 0.003,   Method: Composition-based stats.
 Identities = 34/136 (25%), Positives = 68/136 (50%), Gaps = 4/136 (2%)
 Frame = +3

Query: 90  HFSTVWLSWDIQGKKFVAMKVV---KSAEHYTETALDEIRLLKSVRNSDPNDPNGEMVVQ 146
           HF+ V L+  +   + VA+KV+   K  E        E+R +K V++     PN   + +
Sbjct: 3   HFAVVKLARHVFTGEKVAVKVIDKTKLDEVSRSHLFQEVRCMKLVQH-----PNVVRLYE 167

Query: 147 LLDDFKISGVNGTHICMVFEV-LGHHLLKWIIKSNYQGLPLPCVKKIIQQVLQGLDYLHT 205
           ++D         T + ++ E+  G  +  +I++ +  GL     K+  +Q+++ + Y H 
Sbjct: 168 VID-------TQTKLYLILELGDGGDMYDYIMRHS-GGLEEKLAKRYFRQIVEAISYCH- 320

Query: 206 KCRIIHTDIKPENILL 221
           K  ++H D+KPEN++ 
Sbjct: 321 KLHVVHRDLKPENVVF 368
>03240
          Length = 1683

 Score = 38.9 bits (89), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 36/145 (24%), Positives = 66/145 (45%)
 Frame = -3

Query: 80   YHVIRKLGWGHFSTVWLSWDIQGKKFVAMKVVKSAEHYTETALDEIRLLKSVRNSDPNDP 139
            +  I+ LG G F  V L          AMK ++ ++      +  ++  + +     N  
Sbjct: 1285 FEKIKTLGVGAFGEVSLCRKNDTGMLYAMKTLRKSDVLKRNQVAHVKAERDILAEADN-- 1112

Query: 140  NGEMVVQLLDDFKISGVNGTHICMVFEVLGHHLLKWIIKSNYQGLPLPCVKKIIQQVLQG 199
              E VV+L   F+    N  +  M + V G  L+  +I+   + L  P  +  + +++Q 
Sbjct: 1111 --EWVVKLYYSFQDH--NYLYFVMDY-VPGGDLMGLLIR--MEILDEPLARFYVAELVQA 953

Query: 200  LDYLHTKCRIIHTDIKPENILLSVN 224
            ++ +H +   IH DIKP+NIL+  N
Sbjct: 952  IESVH-RMGFIHRDIKPDNILIDRN 881
>00300
          Length = 2318

 Score = 38.5 bits (88), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 22/65 (33%), Positives = 30/65 (46%), Gaps = 9/65 (13%)
 Frame = -1

Query: 485  QVKIADLGNACWVHKH------FTEDIQTRQYRSLEVLIGS---GYNTPADIWSTACMAF 535
             VK+ D G +  +  H      F   + T  Y + EV   +   GY   ADIWS  C+  
Sbjct: 1253 HVKLGDFGCSVKLKSHTTMPGEFHNLVGTTAYMAPEVFTQNDQGGYGRAADIWSLGCVVI 1074

Query: 536  ELATG 540
            E+ATG
Sbjct: 1073 EMATG 1059

 Score = 34.7 bits (78), Expect = 0.13,   Method: Compositional matrix adjust.
 Identities = 32/151 (21%), Positives = 70/151 (46%), Gaps = 3/151 (1%)
 Frame = -1

Query: 77   NGRYHVIRKLGWGHFSTVWLSWDIQGKKFVAMKVVKSAEHYTET---ALDEIRLLKSVRN 133
            N R+    K+G G F  V+ + ++   + +A+K +K   +  +      DEI++ + +++
Sbjct: 1661 NFRWQRGNKIGEGQFGKVYTAVNMSTGELMALKEMKFQPNDLQQLREMCDEIKIFEGIQH 1482

Query: 134  SDPNDPNGEMVVQLLDDFKISGVNGTHICMVFEVLGHHLLKWIIKSNYQGLPLPCVKKII 193
             +           L+  + +  V+   + M  E      ++   K    GLP   +++  
Sbjct: 1481 EN-----------LVKYYGVE-VHKDEMLMFMEYCDTGTIEEAAK---MGLPEYLIRRYT 1347

Query: 194  QQVLQGLDYLHTKCRIIHTDIKPENILLSVN 224
            ++++  +++LH    I+H DIK  NI L+ N
Sbjct: 1346 REIVLAVNHLHENS-IVHRDIKGANIFLTSN 1257
>04591
          Length = 1117

 Score = 37.7 bits (86), Expect = 0.016,   Method: Compositional matrix adjust.
 Identities = 18/33 (54%), Positives = 25/33 (75%)
 Frame = -2

Query: 190 KKIIQQVLQGLDYLHTKCRIIHTDIKPENILLS 222
           K ++ Q+L GL Y+HTK +I+H DIK  NILL+
Sbjct: 888 KNLMSQLLNGLFYIHTK-QILHRDIKAANILLT 793
>19301
          Length = 712

 Score = 37.7 bits (86), Expect = 0.016,   Method: Compositional matrix adjust.
 Identities = 34/134 (25%), Positives = 61/134 (45%), Gaps = 3/134 (2%)
 Frame = +2

Query: 95  WLSWDIQGKKFVAMKVVKSAEHYTETALDEIRLLK--SVRN-SDPNDPNGEMVVQLLDDF 151
           WL    QG  F+     +      E A+ ++R +K   +RN    N PN       +  F
Sbjct: 326 WLGSGAQGAVFLGKLCAE------EVAVKKVRDIKETDIRNLRKLNHPN-------IISF 466

Query: 152 KISGVNGTHICMVFEVLGHHLLKWIIKSNYQGLPLPCVKKIIQQVLQGLDYLHTKCRIIH 211
           K         C++ E   +  L  +++   + +P   V    +Q+  G++YLH+  +IIH
Sbjct: 467 KGVCTQAPCYCIIMEYCPYGQLYEVLRDGKE-IPPALVLDWSKQIASGMNYLHSH-KIIH 640

Query: 212 TDIKPENILLSVNE 225
            D+K  N+L++ N+
Sbjct: 641 RDLKSPNVLVAKND 682
>31885
          Length = 529

 Score = 37.4 bits (85), Expect = 0.017,   Method: Compositional matrix adjust.
 Identities = 18/34 (52%), Positives = 25/34 (73%)
 Frame = -2

Query: 188 CVKKIIQQVLQGLDYLHTKCRIIHTDIKPENILL 221
           CVK  + Q+   LDYL ++ +I+H DIKP+NILL
Sbjct: 369 CVKFYLCQLALVLDYLRSQ-KIVHRDIKPDNILL 271
>18921
          Length = 697

 Score = 37.0 bits (84), Expect = 0.027,   Method: Compositional matrix adjust.
 Identities = 39/143 (27%), Positives = 69/143 (48%)
 Frame = +2

Query: 80  YHVIRKLGWGHFSTVWLSWDIQGKKFVAMKVVKSAEHYTETALDEIRLLKSVRNSDPNDP 139
           + ++ KLG G + +V+ S   +  + +A+K V       +T L EI  +K +  S     
Sbjct: 35  FDILGKLGEGSYGSVFKSLHKETGQVLAIKQVP-----VDTDLQEI--IKEI--SIMQQC 187

Query: 140 NGEMVVQLLDDFKISGVNGTHICMVFEVLGHHLLKWIIKSNYQGLPLPCVKKIIQQVLQG 199
           + + +V+    +       T + +V E  G   +  I++   + L    +  I+   L+G
Sbjct: 188 DSKYIVKYYGSY----FKNTDLWIVMEYCGAGSVSDIMRLRNKTLVEREIATILYYTLKG 355

Query: 200 LDYLHTKCRIIHTDIKPENILLS 222
           L YLH++ R IH DIK  NILL+
Sbjct: 356 LXYLHSR-RKIHRDIKAGNILLN 421

 Score = 32.7 bits (73), Expect = 0.46,   Method: Compositional matrix adjust.
 Identities = 25/78 (32%), Positives = 35/78 (44%), Gaps = 3/78 (3%)
 Frame = +2

Query: 466 FSAGNFLINPLEPKNAEKLQVKIADLGNACWVHKHFTED---IQTRQYRSLEVLIGSGYN 522
             AGN L+N        +   K+AD G A  +     +    I T  + + EV+   GY+
Sbjct: 395 IKAGNILLN-------NEGHAKLADFGVAGQLTDTMAKRNTVIGTPYWMAPEVIQEIGYD 553

Query: 523 TPADIWSTACMAFELATG 540
             ADIWS    A E+A G
Sbjct: 554 CVADIWSLGITALEMAEG 607
>13592
          Length = 980

 Score = 37.0 bits (84), Expect = 0.027,   Method: Compositional matrix adjust.
 Identities = 20/64 (31%), Positives = 32/64 (50%), Gaps = 9/64 (14%)
 Frame = +2

Query: 486 VKIADLGNACWVHKHFTED------IQTRQYRSLEVLIGS---GYNTPADIWSTACMAFE 536
           +K+ D G+A  +  H T        + T+ Y + EV   +   G+   ADIWS  C+  E
Sbjct: 401 LKLGDFGSAVKIQAHTTVPGELQGYVGTQAYMAPEVFTKTNSDGHGRLADIWSVGCVVVE 580

Query: 537 LATG 540
           +A+G
Sbjct: 581 MASG 592
>21079
          Length = 878

 Score = 36.6 bits (83), Expect = 0.035,   Method: Compositional matrix adjust.
 Identities = 20/61 (32%), Positives = 37/61 (60%), Gaps = 1/61 (1%)
 Frame = +1

Query: 161 ICMVFEVLGH-HLLKWIIKSNYQGLPLPCVKKIIQQVLQGLDYLHTKCRIIHTDIKPENI 219
           + +V E +G   L + +I+ ++      CV   ++Q+  G+ Y+HT+  I+H D+KPEN+
Sbjct: 49  MVLVMEFVGAGELFERVIRDDFVLTERDCVH-FVRQICSGVGYMHTQ-SILHLDLKPENV 222

Query: 220 L 220
           L
Sbjct: 223 L 225
>18481
          Length = 437

 Score = 35.4 bits (80), Expect = 0.080,   Method: Composition-based stats.
 Identities = 19/61 (31%), Positives = 34/61 (55%)
 Frame = -1

Query: 163 MVFEVLGHHLLKWIIKSNYQGLPLPCVKKIIQQVLQGLDYLHTKCRIIHTDIKPENILLS 222
           +V E+LG  L +  +    +   L  +  +  Q+L  L+++H KC  IH D+KP+N L+ 
Sbjct: 266 LVMELLGPSLEELFVICKRR-FTLKTILMVSDQLLSRLEFIHQKC-FIHRDLKPDNFLMG 93

Query: 223 V 223
           +
Sbjct: 92  L 90
>02638
          Length = 1490

 Score = 34.7 bits (78), Expect = 0.12,   Method: Compositional matrix adjust.
 Identities = 19/65 (29%), Positives = 31/65 (47%)
 Frame = +1

Query: 505 IQTRQYRSLEVLIGSGYNTPADIWSTACMAFELATGDYLFEPHSGEDYTRDEDHIALIIE 564
           + T  + + EVL G  Y    D+WS  C+  E+ T      P +  D +   +H+ALI +
Sbjct: 19  LGTIAFMAPEVLRGESYGRACDVWSVGCVMIEMCTCR---PPWNSHDIS---NHLALIFK 180

Query: 565 LLGKV 569
           +   V
Sbjct: 181 IASSV 195
>31489
          Length = 329

 Score = 34.7 bits (78), Expect = 0.12,   Method: Composition-based stats.
 Identities = 21/60 (35%), Positives = 38/60 (63%)
 Frame = +3

Query: 161 ICMVFEVLGHHLLKWIIKSNYQGLPLPCVKKIIQQVLQGLDYLHTKCRIIHTDIKPENIL 220
           I +VF+++   L + II S+ Q L    ++  + Q+L+GL Y+H+   ++H D+KP N+L
Sbjct: 93  IHVVFDLMESDLHR-IIYSD-QPLTEEHIRYFLYQILRGLKYIHS-ANVVHRDLKPSNLL 263
>01392
          Length = 1806

 Score = 34.7 bits (78), Expect = 0.13,   Method: Compositional matrix adjust.
 Identities = 14/29 (48%), Positives = 22/29 (75%)
 Frame = -1

Query: 192  IIQQVLQGLDYLHTKCRIIHTDIKPENIL 220
            +++ + + LD+LH+K  I H D+KPENIL
Sbjct: 1776 VVRHIARALDFLHSK-GIAHRDLKPENIL 1693

 Score = 31.2 bits (69), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 14/42 (33%), Positives = 25/42 (59%), Gaps = 4/42 (9%)
 Frame = -1

Query: 609  YEWPQEE----AAGFTDFLLPMLELMPEKRATAAECLRHPWL 646
            Y++P +E    ++   D +  +L   P KR +AA+ L+HPW+
Sbjct: 1356 YKFPSQEWTSISSSAKDLIRHLLVREPRKRYSAADVLKHPWI 1231
>23319
          Length = 2235

 Score = 34.3 bits (77), Expect = 0.18,   Method: Compositional matrix adjust.
 Identities = 34/137 (24%), Positives = 53/137 (38%), Gaps = 4/137 (2%)
 Frame = +3

Query: 514 EVLIGSGYNTPADIWSTACMAFELATGDYLFEPHSGEDYTRDEDHIALIIELLGKVPRKL 573
           +V     Y+T  D+WS  C+  ELA       P  G D   D+D +  I +LLG      
Sbjct: 6   DVYXAKMYSTSIDMWSAGCIFAELANAGRPLFP--GND---DDDQLKRIFKLLGT----- 155

Query: 574 IVAGKYSKEFFTKKGDLKHITKLKPWGLLEVLVEKYEW----PQEEAAGFTDFLLPMLEL 629
                        +     +T+L  + +  +      W    P+  + G  D L  +L  
Sbjct: 156 -----------PTEDQWPGMTQLPNYRMFPMYHVTTTWQQVVPKLNSKG-RDLLQCLLVC 299

Query: 630 MPEKRATAAECLRHPWL 646
            P  R +A E L+HP+ 
Sbjct: 300 CPSDRMSADEALQHPYF 350
>14420
          Length = 528

 Score = 33.9 bits (76), Expect = 0.19,   Method: Compositional matrix adjust.
 Identities = 29/111 (26%), Positives = 53/111 (47%), Gaps = 5/111 (4%)
 Frame = +2

Query: 119 ETALDEIRLLKSVRNSDPNDPNGEMVVQLLDDFKISGVNGTHICMVFEVLGHHLLKWIIK 178
           E  ++EI +++   N +PN      +V  LD + +    G  + +V E L    L  ++ 
Sbjct: 35  ELIINEILVMR--ENQNPN------IVNYLDSYLV----GEELWVVMEFLAGGSLTDVVT 178

Query: 179 SNYQGLPLPC-----VKKIIQQVLQGLDYLHTKCRIIHTDIKPENILLSVN 224
                    C     +  + ++ LQ L++LH   ++IH DIK +NILL ++
Sbjct: 179 ET-------CMDEGQIAAVCRECLQALEFLHEN-QVIHRDIKSDNILLGMD 307
>15910
          Length = 1361

 Score = 33.5 bits (75), Expect = 0.25,   Method: Compositional matrix adjust.
 Identities = 40/164 (24%), Positives = 63/164 (38%), Gaps = 2/164 (1%)
 Frame = +2

Query: 485 QVKIADLGNACWVHK--HFTEDIQTRQYRSLEVLIGSGYNTPADIWSTACMAFELATGDY 542
           ++K+AD G +  +      +    T  Y + EVL G  Y    D+WS   +A+ L  G  
Sbjct: 587 KLKLADFGLSRIIEPEVQMSTVCGTPGYCAPEVLKGDKYTPSVDMWSVGVIAYILLCG-- 760

Query: 543 LFEPHSGEDYTRDEDHIALIIELLGKVPRKLIVAGKYSKEFFTKKGDLKHITKLKPWGLL 602
            +EP   E+                ++ RK+I            KG+ K           
Sbjct: 761 -YEPFFAENEF--------------EMYRKII------------KGEYKF---------- 829

Query: 603 EVLVEKYEWPQEEAAGFTDFLLPMLELMPEKRATAAECLRHPWL 646
                  E+  E +    D +  +L + P+KR TA E LR PW+
Sbjct: 830 -----DEEYWSEISENAKDVVRKLLVIDPKKRLTATEALRLPWV 946

 Score = 31.6 bits (70), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 12/30 (40%), Positives = 20/30 (66%)
 Frame = +2

Query: 191 KIIQQVLQGLDYLHTKCRIIHTDIKPENIL 220
           + I  +L G+ Y+H    ++H D+KPEN+L
Sbjct: 476 RAISDILHGVQYIHAN-GVVHRDLKPENLL 562
>00392
          Length = 668

 Score = 33.5 bits (75), Expect = 0.27,   Method: Compositional matrix adjust.
 Identities = 22/67 (32%), Positives = 39/67 (58%), Gaps = 1/67 (1%)
 Frame = +3

Query: 157 NGTHICMVFEVLGHHLLKWIIKSNYQGLPLPCVKKIIQQVLQGLDYLHTKC-RIIHTDIK 215
           N   I +V E++    LK  +K  ++   +  +K   +QVL+GL +LHT+   +IH D+K
Sbjct: 159 NRKVIILVTELMTSGTLKTYLK-RFKKPNVKILKNWCRQVLKGLYFLHTRTPPVIHRDLK 335

Query: 216 PENILLS 222
            +NI ++
Sbjct: 336 CDNIFIT 356
>19094
          Length = 898

 Score = 33.1 bits (74), Expect = 0.33,   Method: Compositional matrix adjust.
 Identities = 17/34 (50%), Positives = 23/34 (67%)
 Frame = +1

Query: 189 VKKIIQQVLQGLDYLHTKCRIIHTDIKPENILLS 222
           +  I+   L+GL YLH++ R IH DIK  NILL+
Sbjct: 64  IATILYYTLKGL*YLHSR-RKIHRDIKAGNILLN 162

 Score = 32.7 bits (73), Expect = 0.44,   Method: Compositional matrix adjust.
 Identities = 26/83 (31%), Positives = 37/83 (44%), Gaps = 3/83 (3%)
 Frame = +1

Query: 466 FSAGNFLINPLEPKNAEKLQVKIADLGNACWVHKHFTED---IQTRQYRSLEVLIGSGYN 522
             AGN L+N        +   K+AD G A  +     +    I T  + + EV+   GY+
Sbjct: 136 IKAGNILLN-------NEGHAKLADFGVAGQLTDTMAKRNTVIGTPYWMAPEVIQEIGYD 294

Query: 523 TPADIWSTACMAFELATGDYLFE 545
             ADIWS    A E+A G+   E
Sbjct: 295 CVADIWSLGITALEMAEGNLHME 363

 Score = 28.9 bits (63), Expect = 7.2,   Method: Compositional matrix adjust.
 Identities = 13/38 (34%), Positives = 21/38 (55%)
 Frame = +3

Query: 609 YEWPQEEAAGFTDFLLPMLELMPEKRATAAECLRHPWL 646
           +  P + +  F DF+   L   PE RATA + L+H ++
Sbjct: 417 FRQPDKWSTEFIDFVSKCLVKNPENRATAVDLLQHDFI 530
>20152
          Length = 445

 Score = 32.7 bits (73), Expect = 0.50,   Method: Compositional matrix adjust.
 Identities = 28/135 (20%), Positives = 47/135 (34%), Gaps = 1/135 (0%)
 Frame = +1

Query: 514 EVLIGSGYNTPA-DIWSTACMAFELATGDYLFEPHSGEDYTRDEDHIALIIELLGKVPRK 572
           E+L+G  Y+ PA D+WS   + + L  G+  F+         D + + +I++        
Sbjct: 4   EILLGDSYDAPAVDVWSLGVILYMLVVGEAPFQ------EANDSETLTMIMDC------- 144

Query: 573 LIVAGKYSKEFFTKKGDLKHITKLKPWGLLEVLVEKYEWPQEEAAGFTDFLLPMLELMPE 632
                                              +Y+ P   +    D +  ML+  P 
Sbjct: 145 -----------------------------------RYQIPPHISHKCQDLIEKMLQREPV 219

Query: 633 KRATAAECLRHPWLN 647
            RA+    L HPWLN
Sbjct: 220 DRASLPHILAHPWLN 264
>06405
          Length = 1965

 Score = 32.7 bits (73), Expect = 0.50,   Method: Compositional matrix adjust.
 Identities = 27/91 (29%), Positives = 46/91 (50%), Gaps = 7/91 (7%)
 Frame = +1

Query: 470 NFLINPLEPKN---AEKLQVKIADLGNACWVHKH-FTEDIQTR---QYRSLEVLIGSGYN 522
           NF+   L  +N   A+   VK+AD G A  +    +T  I  +   ++ + E L  + ++
Sbjct: 613 NFIHRDLAARNCLVADSNMVKVADFGLARLMKDDTYTAHIGAKFPIKWTAPEGLAFNRFS 792

Query: 523 TPADIWSTACMAFELATGDYLFEPHSGEDYT 553
           T +DIW+   + +ELAT  Y   P+ G + T
Sbjct: 793 TRSDIWAFGVLLWELAT--YGMSPYPGVELT 879
>00715
          Length = 1788

 Score = 32.0 bits (71), Expect = 0.84,   Method: Compositional matrix adjust.
 Identities = 19/60 (31%), Positives = 32/60 (53%)
 Frame = +1

Query: 163 MVFEVLGHHLLKWIIKSNYQGLPLPCVKKIIQQVLQGLDYLHTKCRIIHTDIKPENILLS 222
           +  E +G   L+ I+  + Q +       +  Q+ +GL YLH+   I+H D+KP N LL+
Sbjct: 166 LAMEYVGPLNLQTILNDHQQDIDSSMRLSLALQMARGLHYLHS-INIVHLDLKPANCLLT 342
>26711
          Length = 405

 Score = 31.6 bits (70), Expect = 0.93,   Method: Composition-based stats.
 Identities = 13/31 (41%), Positives = 23/31 (74%)
 Frame = -2

Query: 192 IIQQVLQGLDYLHTKCRIIHTDIKPENILLS 222
           +++QVL  L ++H +  ++H D+KP N+LLS
Sbjct: 401 VVKQVLDILQHVHAQ-GVVHMDLKPSNLLLS 312
>17637
          Length = 447

 Score = 31.6 bits (70), Expect = 1.1,   Method: Composition-based stats.
 Identities = 18/56 (32%), Positives = 29/56 (51%), Gaps = 4/56 (7%)
 Frame = +1

Query: 509 QYRSLEVLIGSGYNTPADIWSTACMAFELATGDYL----FEPHSGEDYTRDEDHIA 560
           ++ SLE L  S YN  +D+WS   + +E+ T   L     +P+  E Y +D   +A
Sbjct: 112 KWLSLEALQKSHYNEGSDVWSFGVLMWEMCTLGKLPYAEIDPYEMEHYLKDGYRLA 279
>06419
          Length = 1120

 Score = 31.2 bits (69), Expect = 1.4,   Method: Compositional matrix adjust.
 Identities = 24/88 (27%), Positives = 39/88 (44%), Gaps = 4/88 (4%)
 Frame = -1

Query: 117  YTETALDEIRLLKSVRNSDPNDPNG---EMVVQLLDDFKISGVNGTHICMVFEVLGHHLL 173
            +T+  L  I +  S+++ D    NG     V Q   DFKISG  G H   + E L + + 
Sbjct: 1057 WTKMILRRIEIFMSLKSRDNTRYNGGNITFVAQFSGDFKISG*VGNHFEKMVEAL-YIIF 881

Query: 174  KWIIKS-NYQGLPLPCVKKIIQQVLQGL 200
            ++++   +   L L C K     +   L
Sbjct: 880  QYLLSEID*DILYLACFKSTFMSIKSSL 797
>13212
          Length = 1067

 Score = 30.8 bits (68), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 19/64 (29%), Positives = 33/64 (51%)
 Frame = -1

Query: 161  ICMVFEVLGHHLLKWIIKSNYQGLPLPCVKKIIQQVLQGLDYLHTKCRIIHTDIKPENIL 220
            I  VF VL    L  I+    + +    +  +  ++   LD+LH +  +IH DIK  N+L
Sbjct: 1058 IVDVFRVLWWGALDSIMVDLEKPMTEAQICYVCHEMCMALDFLH-RHHVIHRDIKAGNVL 882

Query: 221  LSVN 224
            L+++
Sbjct: 881  LTID 870

 Score = 29.6 bits (65), Expect = 3.6,   Method: Compositional matrix adjust.
 Identities = 42/178 (23%), Positives = 60/178 (33%), Gaps = 15/178 (8%)
 Frame = -1

Query: 485 QVKIADLGNACWVHKHFTEDIQTRQYRS---------------LEVLIGSGYNTPADIWS 529
           +VK+AD G +        ++ QT+Q R                 E L  + Y+  ADIWS
Sbjct: 866 EVKLADFGVSA-------KNTQTQQKRDTFIGTPYWMAPEVVLCETLKDTPYDFKADIWS 708

Query: 530 TACMAFELATGDYLFEPHSGEDYTRDEDHIALIIELLGKVPRKLIVAGKYSKEFFTKKGD 589
                 E A      EP + E +                 P ++++           K D
Sbjct: 707 LGVTLIEFAQ----IEPPNKEMH-----------------PMRVLIK--------IHKSD 615

Query: 590 LKHITKLKPWGLLEVLVEKYEWPQEEAAGFTDFLLPMLELMPEKRATAAECLRHPWLN 647
              + K K W  L                F DF+   L   P  R TAAE L HP++ 
Sbjct: 614 PPTLEKPKKWTKL----------------FKDFIAKCLVKDPNLRPTAAELLEHPFMK 489
>32357
          Length = 625

 Score = 30.8 bits (68), Expect = 1.8,   Method: Composition-based stats.
 Identities = 18/52 (34%), Positives = 32/52 (61%), Gaps = 4/52 (7%)
 Frame = -2

Query: 75  LFNGRYHVIRKLGWGHFSTVWLSWDIQGKKFVAMKV-VKSAEH---YTETAL 122
           L NG+Y +++K+G G F  ++L       + VA+K+ +K+A+H   Y E+ L
Sbjct: 447 LVNGKYRLMKKIGSGSFGEIYLGVHNTSGEEVAVKLELKNAKHPQLYYESKL 292
>27405
          Length = 532

 Score = 30.8 bits (68), Expect = 1.9,   Method: Composition-based stats.
 Identities = 12/30 (40%), Positives = 23/30 (76%)
 Frame = -3

Query: 195 QVLQGLDYLHTKCRIIHTDIKPENILLSVN 224
           +V+ GL+++H++  +++ D+KP NILL  N
Sbjct: 230 EVMLGLEHMHSRF-VVYRDLKPANILLDEN 144
>14477
          Length = 493

 Score = 30.4 bits (67), Expect = 2.3,   Method: Compositional matrix adjust.
 Identities = 15/38 (39%), Positives = 24/38 (63%)
 Frame = -1

Query: 184 LPLPCVKKIIQQVLQGLDYLHTKCRIIHTDIKPENILL 221
           LPL  + +++ QV QG++YL    + +H D+   NILL
Sbjct: 199 LPLWNILELMWQVSQGMEYLEAN-KFVHRDLAARNILL 89
>26052
          Length = 562

 Score = 30.4 bits (67), Expect = 2.3,   Method: Composition-based stats.
 Identities = 15/49 (30%), Positives = 27/49 (55%)
 Frame = -3

Query: 165 FEVLGHHLLKWIIKSNYQGLPLPCVKKIIQQVLQGLDYLHTKCRIIHTD 213
            E+L  +LL W+ K +  G+P   +K I +++   L +L  +  I+H D
Sbjct: 146 LELLQGNLLDWLCKHHPNGVPPSVMKTITKRLFSALSFLRREA-IVHGD 3
>26560
          Length = 398

 Score = 30.4 bits (67), Expect = 2.4,   Method: Composition-based stats.
 Identities = 12/30 (40%), Positives = 23/30 (76%)
 Frame = -1

Query: 195 QVLQGLDYLHTKCRIIHTDIKPENILLSVN 224
           +V+ GL+++H++  +++ D+KP NILL  N
Sbjct: 332 EVMLGLEHMHSRF-VVYRDLKPANILLDEN 246
>25725
          Length = 661

 Score = 30.0 bits (66), Expect = 2.9,   Method: Compositional matrix adjust.
 Identities = 14/29 (48%), Positives = 20/29 (68%)
 Frame = +1

Query: 375 RHKEDLHNANDCDVHTLKQEPSFLNSSNG 403
           RH   LH++N+C VH   + P+ L+SSNG
Sbjct: 79  RHPNILHSSNECAVH---RPPNILHSSNG 156
>12786
          Length = 460

 Score = 30.0 bits (66), Expect = 3.4,   Method: Compositional matrix adjust.
 Identities = 14/40 (35%), Positives = 25/40 (62%)
 Frame = -3

Query: 182 QGLPLPCVKKIIQQVLQGLDYLHTKCRIIHTDIKPENILL 221
           QGL    +K   +++L+ +  LH +  +IH+D+KP N +L
Sbjct: 425 QGLDRMMIKFYWREMLRAVKALHNEG-VIHSDLKPANFML 309
>03508
          Length = 1463

 Score = 29.6 bits (65), Expect = 3.8,   Method: Compositional matrix adjust.
 Identities = 12/45 (26%), Positives = 26/45 (57%)
 Frame = +1

Query: 177 IKSNYQGLPLPCVKKIIQQVLQGLDYLHTKCRIIHTDIKPENILL 221
            K  YQ      ++  + ++++ LD+ H+   I+H D+KP N+++
Sbjct: 841 FKQLYQTFTDYDIRFYLYELMKALDFCHSMG-IMHRDVKPHNVMI 972
>25951
          Length = 531

 Score = 29.6 bits (65), Expect = 4.1,   Method: Composition-based stats.
 Identities = 20/54 (37%), Positives = 31/54 (57%)
 Frame = +3

Query: 143 MVVQLLDDFKISGVNGTHICMVFEVLGHHLLKWIIKSNYQGLPLPCVKKIIQQV 196
           +V+ +   FK S +  T +C+   VL + LL   IKSN QGLP   V+ + ++V
Sbjct: 288 IVLMIYCHFKSSQI--TKVCL--NVLSYDLLTXQIKSNQQGLPERLVRDLQKKV 437
>27546
          Length = 426

 Score = 29.6 bits (65), Expect = 4.2,   Method: Composition-based stats.
 Identities = 15/28 (53%), Positives = 19/28 (67%)
 Frame = -1

Query: 195 QVLQGLDYLHTKCRIIHTDIKPENILLS 222
           Q+ + L YLH+   I H D+K ENILLS
Sbjct: 156 QMAKALQYLHSH-DIAHRDLKCENILLS 76
>27274
          Length = 396

 Score = 29.3 bits (64), Expect = 4.8,   Method: Composition-based stats.
 Identities = 28/133 (21%), Positives = 46/133 (34%)
 Frame = -1

Query: 514 EVLIGSGYNTPADIWSTACMAFELATGDYLFEPHSGEDYTRDEDHIALIIELLGKVPRKL 573
           E+L G  +    D+WS   +  EL +G   FEP  G                  ++ R +
Sbjct: 375 ELLRGQQHGPTVDMWSLGILLHELLSGHVPFEPERGSR----------------QMARNM 244

Query: 574 IVAGKYSKEFFTKKGDLKHITKLKPWGLLEVLVEKYEWPQEEAAGFTDFLLPMLELMPEK 633
           +    Y++       D+     L   G                    DFL  +++L   K
Sbjct: 243 MAV--YAQIIRGSSRDVCDGLALSTHG-------------------ADFLRRLVQLEDTK 127

Query: 634 RATAAECLRHPWL 646
           R T+ +   HPW+
Sbjct: 126 RLTSQQAFSHPWI 88
>21433
          Length = 590

 Score = 29.3 bits (64), Expect = 4.8,   Method: Composition-based stats.
 Identities = 13/26 (50%), Positives = 18/26 (69%)
 Frame = +2

Query: 193 IQQVLQGLDYLHTKCRIIHTDIKPEN 218
           I Q+   L+Y H + ++IH DIKPEN
Sbjct: 185 IYQLSSALEYCHYR-KVIHRDIKPEN 259
>12721
          Length = 821

 Score = 29.3 bits (64), Expect = 4.8,   Method: Compositional matrix adjust.
 Identities = 30/138 (21%), Positives = 64/138 (46%)
 Frame = +1

Query: 85  KLGWGHFSTVWLSWDIQGKKFVAMKVVKSAEHYTETALDEIRLLKSVRNSDPNDPNGEMV 144
           K+G G    V ++    G++    K+    +   E   +E+ +++     D + PN   +
Sbjct: 109 KIGEGSTGIVCIATSRDGRQMAVKKMDLRKQQRRELLFNEVVVMR-----DYHHPN---I 264

Query: 145 VQLLDDFKISGVNGTHICMVFEVLGHHLLKWIIKSNYQGLPLPCVKKIIQQVLQGLDYLH 204
           V++ + + ++      + +V E +    L  I+ +N   +    +  + +  L+ L +LH
Sbjct: 265 VEMYNSYLVND----ELWVVMEFMEGGALTDIVTNNR--MDEVQIATVCRACLKALAFLH 426

Query: 205 TKCRIIHTDIKPENILLS 222
               +IH DIK ++ILLS
Sbjct: 427 ANG-VIHRDIKSDSILLS 477
>18484
          Length = 635

 Score = 29.3 bits (64), Expect = 5.0,   Method: Compositional matrix adjust.
 Identities = 21/73 (28%), Positives = 31/73 (42%), Gaps = 6/73 (8%)
 Frame = +1

Query: 485 QVKIADLGNACWVHKHFTEDIQTR------QYRSLEVLIGSGYNTPADIWSTACMAFELA 538
            +KIAD G      +  T D  TR       Y + E+++   Y+   D W+   + FE+ 
Sbjct: 157 HIKIADFGMC---KEGMTGDATTRTFCGTPDYIAPEIVLYQPYSKSVDWWAYGVLLFEML 327

Query: 539 TGDYLFEPHSGED 551
            G     P  GED
Sbjct: 328 AGQ---PPFDGED 357
>30755
          Length = 1137

 Score = 29.3 bits (64), Expect = 5.7,   Method: Compositional matrix adjust.
 Identities = 37/127 (29%), Positives = 50/127 (39%), Gaps = 11/127 (8%)
 Frame = +2

Query: 458 GALDSKGKFSAGNFLINPLEPKNAEKLQVKIADLGNACWVHKHFTEDIQ----------T 507
           G L S+G       L N L  K+     +K+AD G  C       EDI           T
Sbjct: 74  GYLHSQGIIYRDLKLENLLLDKDG---HIKVADFG-LC------KEDITYGRTTKTFCGT 223

Query: 508 RQYRSLEVLIGSGYNTPADIWSTACMAFELATGDYLFEPHSGEDYTRDEDHI-ALIIELL 566
            +Y + EVL  + Y    D W T  + +E+  G   F       Y RD D +  LI+   
Sbjct: 224 PEYLAPEVLDDNDYGRAVDWWGTGVVMYEMICGRLPF-------YNRDHDVLFTLILVED 382

Query: 567 GKVPRKL 573
            K PR +
Sbjct: 383 VKFPRNI 403
>36002
          Length = 253

 Score = 28.5 bits (62), Expect = 7.7,   Method: Compositional matrix adjust.
 Identities = 14/42 (33%), Positives = 23/42 (54%), Gaps = 4/42 (9%)
 Frame = +1

Query: 609 YEWPQEEAAGFT----DFLLPMLELMPEKRATAAECLRHPWL 646
           Y +P  E +  +    D +  +L   P KR +AA+ L+HPW+
Sbjct: 85  YFFPSMEWSAISSSAKDLIRHLLVREPRKRYSAADVLKHPWV 210
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6680043|ref|NP_032167.1| guanine nucleotide binding
protein, alpha transducing 2 [Mus musculus]
         (354 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

11965                                                                 313   9e-86
13527                                                                 206   9e-54
29196                                                                 129   2e-30
20516                                                                 108   3e-24
34094                                                                  62   3e-10
08153                                                                  41   7e-04
09827                                                                  40   0.001
10862                                                                  39   0.003
18949                                                                  37   0.017
11378                                                                  36   0.029
18208                                                                  31   0.79 
24860                                                                  29   2.6  
26908                                                                  28   8.2  
>11965
          Length = 3256

 Score =  313 bits (801), Expect = 9e-86,   Method: Compositional matrix adjust.
 Identities = 145/222 (65%), Positives = 176/222 (79%)
 Frame = +1

Query: 133 DGGVQACFDRAAEFQLNDSASYYLNQLDRITDPNYLPNEQDVLRSRVKTTGIIETKFSVK 192
           D GVQ CF R+ E+QLNDSA Y+L+ LDR+   +Y+P EQD+LR+RVKTTGI+E  FS K
Sbjct: 1   DSGVQDCFSRSNEYQLNDSAKYFLDDLDRLGTKDYMPTEQDILRTRVKTTGIVEVHFSFK 180

Query: 193 DLNFRMFDVGGQRSERKKWIHCFEGVTCIIFCAALSAYDMVLVEDDEVNRMHESLHLFNS 252
           +LNF++FDVGGQRSERKKWIHCFE VT IIFC A+S YD VL ED+  NRM ESL LF+S
Sbjct: 181 NLNFKLFDVGGQRSERKKWIHCFEDVTAIIFCVAMSEYDQVLHEDETTNRMQESLKLFDS 360

Query: 253 ICNHKFFAATSIVLFLNKKDLFEEKIKKVHLSICFPEYDGNNSYEDAGNYIKSQFLDLNM 312
           ICN+K+F  TSI+LFLNKKDLFEEKIKK  L++CFPEY G  +YE+   YI++QF   N 
Sbjct: 361 ICNNKWFTDTSIILFLNKKDLFEEKIKKSPLTVCFPEYTGKQTYEEVAAYIQAQFEAKN- 537

Query: 313 RKDVKEIYSHMTCATDTQNVKFVFDAVTDIIIKENLKDCGLF 354
           +   KEIY H TCATDT N++FVFDAVTD+II  NL+ CGL+
Sbjct: 538 KSSQKEIYCHQTCATDTNNIQFVFDAVTDVIIANNLRGCGLY 663
>13527
          Length = 1091

 Score =  206 bits (525), Expect = 9e-54,   Method: Compositional matrix adjust.
 Identities = 101/198 (51%), Positives = 141/198 (71%), Gaps = 1/198 (0%)
 Frame = -2

Query: 1    MGSGISAEDKELARRSKELEKKLQEDADKEAKTVKLLLLGAGESGKSTIVKQMKIIHQDG 60
            MG  +SAE++    RSK +EK L+ED  + AK +KLLLLGAGESGKSTIVKQMKIIH+ G
Sbjct: 1042 MGCTLSAEERAAMERSKAIEKNLKEDGMQAAKDIKLLLLGAGESGKSTIVKQMKIIHEGG 863

Query: 61   YSPEECLEFKSVIYGNVLQSILAIIRAMSTLGIDYAE-PSCADAGRQLNNLADSTEEGTM 119
            ++ E+  +++ V++ N +QS++AIIRAM TL I + +    +DA   L+ +A   +    
Sbjct: 862  FTSEDNKQYRPVVFSNTIQSLVAIIRAMGTLSIPFGDNERESDAKMVLDVIARMEDTEPF 683

Query: 120  PPELVDVIRKLWKDGGVQACFDRAAEFQLNDSASYYLNQLDRITDPNYLPNEQDVLRSRV 179
              EL+  + +LW D GVQ CF R+ E+QLNDSA Y+L+ LDR+   +Y+P EQD+LR+RV
Sbjct: 682  SEELLAAMERLWMDSGVQDCFSRSNEYQLNDSAKYFLDDLDRLGTKDYMPTEQDILRTRV 503

Query: 180  KTTGIIETKFSVKDLNFR 197
            KTTGI+E  FS K+LNF+
Sbjct: 502  KTTGIVEVHFSFKNLNFK 449
>29196
          Length = 431

 Score =  129 bits (323), Expect = 2e-30,   Method: Compositional matrix adjust.
 Identities = 73/147 (49%), Positives = 90/147 (61%), Gaps = 6/147 (4%)
 Frame = -2

Query: 127 IRKLWKDGGVQACFDRAAE-----FQLNDSASYYLNQLDRITD-PNYLPNEQDVLRSRVK 180
           +++LW D GVQ C  RAA        LN S    +    RIT  PN     +       +
Sbjct: 424 MKRLWLDSGVQEC-SRAATNTN*TIPLNISWMI*IG*ALRITSQPN-----RTFCAPESR 263

Query: 181 TTGIIETKFSVKDLNFRMFDVGGQRSERKKWIHCFEGVTCIIFCAALSAYDMVLVEDDEV 240
              +      +K+LNF++FDVGGQRSERKKWIHCFE VT IIFC A+S YD VL ED+  
Sbjct: 262 PPAL*RFISPLKNLNFKLFDVGGQRSERKKWIHCFEDVTAIIFCVAMSEYDQVLHEDETT 83

Query: 241 NRMHESLHLFNSICNHKFFAATSIVLF 267
           NRM ESL LF+SICN+K+F  TSI+LF
Sbjct: 82  NRMQESLKLFDSICNNKWFTDTSIILF 2
>20516
          Length = 534

 Score =  108 bits (270), Expect = 3e-24,   Method: Compositional matrix adjust.
 Identities = 59/149 (39%), Positives = 84/149 (56%)
 Frame = +2

Query: 201 VGGQRSERKKWIHCFEGVTCIIFCAALSAYDMVLVEDDEVNRMHESLHLFNSICNHKFFA 260
            GGQRS+R+KW  CF G+T I+F AA S +D VL+ED + NR+ ES  +F +I N+K F+
Sbjct: 77  TGGQRSQRQKWYQCFVGITSILFLAASSEFDQVLMEDRKTNRLQESCDIFETIINNKSFS 256

Query: 261 ATSIVLFLNKKDLFEEKIKKVHLSICFPEYDGNNSYEDAGNYIKSQFLDLNMRKDVKEIY 320
             SI+LFLNK DL ++K     L   F  + G +        I +  +        +   
Sbjct: 257 GVSIILFLNKMDLLQDKN*ACQLRRLFSRFSG*SQGH*CSQSI*ASAV*FAPT*SKQTFV 436

Query: 321 SHMTCATDTQNVKFVFDAVTDIIIKENLK 349
            H T A DT+N+K VF  V D I+ +NL+
Sbjct: 437 HHFTTAIDTENIKHVFQDVKDTILHDNLR 523
>34094
          Length = 452

 Score = 62.0 bits (149), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 23/45 (51%), Positives = 36/45 (80%)
 Frame = +1

Query: 54  KIIHQDGYSPEECLEFKSVIYGNVLQSILAIIRAMSTLGIDYAEP 98
           +IIH+ GYS EECL++K V+Y N +QS++AI+RAM+ L +++  P
Sbjct: 103 RIIHEKGYSQEECLQYKPVVYSNAIQSMIAIVRAMNLLSVEFGHP 237
>08153
          Length = 1703

 Score = 40.8 bits (94), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 25/97 (25%), Positives = 45/97 (46%)
 Frame = +1

Query: 177 SRVKTTGIIETKFSVKDLNFRMFDVGGQRSERKKWIHCFEGVTCIIFCAALSAYDMVLVE 236
           + + T G        K+++F ++DVGGQ   R  W H F+    +IF          +V+
Sbjct: 163 TTIPTIGFNVETVEYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIF----------VVD 312

Query: 237 DDEVNRMHESLHLFNSICNHKFFAATSIVLFLNKKDL 273
            ++  R++E+      + N        I++F NK+DL
Sbjct: 313 SNDRERINEAKEELARMLNEDDLRDAIILVFANKQDL 423
>09827
          Length = 1201

 Score = 40.0 bits (92), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 24/97 (24%), Positives = 44/97 (45%)
 Frame = -3

Query: 177  SRVKTTGIIETKFSVKDLNFRMFDVGGQRSERKKWIHCFEGVTCIIFCAALSAYDMVLVE 236
            + + T G        K+++F ++DVGGQ   R  W H F+    +IF          +V+
Sbjct: 1034 TTIPTIGFNVETVEYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIF----------VVD 885

Query: 237  DDEVNRMHESLHLFNSICNHKFFAATSIVLFLNKKDL 273
             ++  R+ E+      + N        +++F NK+DL
Sbjct: 884  SNDKERVQEAREELTRMLNEDELRDAVLLVFANKQDL 774
>10862
          Length = 2896

 Score = 38.9 bits (89), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 23/84 (27%), Positives = 41/84 (48%)
 Frame = -3

Query: 190  SVKDLNFRMFDVGGQRSERKKWIHCFEGVTCIIFCAALSAYDMVLVEDDEVNRMHESLHL 249
             +++  F ++DVGGQ   R  W H + G   +IF          +V+  + +R+ E+   
Sbjct: 2498 QLQECQFNVWDVGGQDKIRPLWRHYYTGTQGLIF----------VVDCADRDRIDEARQE 2349

Query: 250  FNSICNHKFFAATSIVLFLNKKDL 273
             + I N +      I++F NK+DL
Sbjct: 2348 LHRIINDREMRDAIILIFANKQDL 2277
>18949
          Length = 414

 Score = 36.6 bits (83), Expect = 0.017,   Method: Compositional matrix adjust.
 Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 1/97 (1%)
 Frame = +3

Query: 177 SRVKTTGIIETK-FSVKDLNFRMFDVGGQRSERKKWIHCFEGVTCIIFCAALSAYDMVLV 235
           S+ + TG+  ++  S+  + F  FD+GG R  R+ W   F  V  I+F        +V V
Sbjct: 3   SQHRPTGLPTSEELSMGGMTFTTFDLGGHRQARRVWKDYFPAVDGIVF--------IVDV 158

Query: 236 EDDEVNRMHESLHLFNSICNHKFFAATSIVLFLNKKD 272
            D E  R+ E+    +S+      A   +++  NK D
Sbjct: 159 HDTE--RITEAKAELDSLLRDDQIADIPVLVLGNKMD 263
>11378
          Length = 1688

 Score = 35.8 bits (81), Expect = 0.029,   Method: Compositional matrix adjust.
 Identities = 28/100 (28%), Positives = 43/100 (43%)
 Frame = +3

Query: 173 DVLRSRVKTTGIIETKFSVKDLNFRMFDVGGQRSERKKWIHCFEGVTCIIFCAALSAYDM 232
           D +   V T      + S+  + F  FD+GG R  R+ W   F  V  I+F        +
Sbjct: 390 DKMAQHVPTLHPTSEELSMGGMRFTTFDLGGHRQARRVWKDYFPAVDGIVF--------L 545

Query: 233 VLVEDDEVNRMHESLHLFNSICNHKFFAATSIVLFLNKKD 272
           V V D E  R+ E+    +S+   +  A   I++  NK D
Sbjct: 546 VDVHDRE--RLVEAKAELDSLMTDEQVANAPILVLGNKID 659
>18208
          Length = 458

 Score = 30.8 bits (68), Expect = 0.79,   Method: Compositional matrix adjust.
 Identities = 14/55 (25%), Positives = 24/55 (43%)
 Frame = -1

Query: 192 KDLNFRMFDVGGQRSERKKWIHCFEGVTCIIFCAALSAYDMVLVEDDEVNRMHES 246
           K     ++D+GGQR  R  W + FE    +I+           ++  +  RM E+
Sbjct: 176 KGFKLNVWDIGGQRRIRPYWKNYFENTDLLIYV----------IDSSDTKRMEET 42

 Score = 29.3 bits (64), Expect = 2.8,   Method: Compositional matrix adjust.
 Identities = 13/41 (31%), Positives = 24/41 (58%)
 Frame = -1

Query: 32  KTVKLLLLGAGESGKSTIVKQMKIIHQDGYSPEECLEFKSV 72
           + +++LLLG   +GK+T++KQ+        +P +    KSV
Sbjct: 305 RELRILLLGLDNAGKTTLLKQLASEDPSHITPTQGFNIKSV 183
>24860
          Length = 730

 Score = 29.3 bits (64), Expect = 2.6,   Method: Compositional matrix adjust.
 Identities = 12/36 (33%), Positives = 24/36 (66%)
 Frame = -1

Query: 45  GKSTIVKQMKIIHQDGYSPEECLEFKSVIYGNVLQS 80
           G++ I K++K+ HQD +S +  L+  + ++ NVL +
Sbjct: 706 GRTKINKKIKVTHQDFHS*DHILKVTTFLHKNVLPT 599
>26908
          Length = 431

 Score = 27.7 bits (60), Expect = 8.2,   Method: Compositional matrix adjust.
 Identities = 11/29 (37%), Positives = 17/29 (58%)
 Frame = +1

Query: 81  ILAIIRAMSTLGIDYAEPSCADAGRQLNN 109
           +L  I + +T+GIDY  P C   G Q+ +
Sbjct: 319 VLITILSSTTVGIDYXFPDCXRQGLQIQD 405
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|82932154|ref|XP_901481.1| PREDICTED: tomosyn isoform
5 [Mus musculus]
         (1155 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

06799                                                                 314   1e-85
01694                                                                 232   6e-61
30464                                                                 180   3e-45
08872                                                                 122   1e-27
37988                                                                  47   1e-06
11187                                                                  45   2e-04
01768                                                                  42   0.001
03387                                                                  40   0.005
01462                                                                  38   0.028
20662                                                                  33   0.58 
15337                                                                  33   0.63 
02948                                                                  33   0.66 
21105                                                                  33   0.70 
00561                                                                  33   0.83 
01598                                                                  32   1.00 
13278                                                                  32   1.2  
16746                                                                  32   2.2  
36468                                                                  31   2.6  
29419                                                                  31   2.9  
02090                                                                  31   3.0  
12841                                                                  31   3.4  
16996                                                                  30   6.0  
08948                                                                  30   6.4  
>06799
          Length = 616

 Score =  314 bits (805), Expect = 1e-85,   Method: Compositional matrix adjust.
 Identities = 141/202 (69%), Positives = 168/202 (83%)
 Frame = +3

Query: 107 FLINEGALVSALADDTLHLWNLRQKRPAVLHSLKFCRERVTFCHLPFQSKWLYVGTERGN 166
           FLINEGALV+  ADDTLHLWN RQK+P ++HSLKF RER+T+CHLPFQSKWLY+GTERGN
Sbjct: 6   FLINEGALVTVCADDTLHLWNYRQKKPEIVHSLKFQRERITYCHLPFQSKWLYIGTERGN 185

Query: 167 IHIVNVESFTLSGYVIMWNKAIELSSKAHPGPVVHISDNPMDEGKLLIGFESGTVVLWDL 226
           +HIVN+ESF LSGY+I WNKAIELS K HPGPVVH+SDNP+D  KLLIGFESG +VLWDL
Sbjct: 186 VHIVNIESFILSGYIINWNKAIELSRKTHPGPVVHLSDNPVDSNKLLIGFESGAIVLWDL 365

Query: 227 KSKKADYRYTYDEAIHSVAWHHEGKQFICSHSDGTLTIWNVRSPAKPVQTITPHGKQLKD 286
           +SK A+ RY   EA+ S+AWH EGKQF+CSHSDG+LT WN+++P KP   + PH K   +
Sbjct: 366 RSKAAECRYNSPEALRSIAWHFEGKQFMCSHSDGSLTTWNLKAPHKPANVLMPHAKVGAE 545

Query: 287 GKKPEPCKPILKVELKTTRSGE 308
           G KP+PCKPI KV  K+ R+GE
Sbjct: 546 G-KPDPCKPITKVAWKSVRNGE 608
>01694
          Length = 944

 Score =  232 bits (592), Expect = 6e-61,   Method: Compositional matrix adjust.
 Identities = 119/272 (43%), Positives = 163/272 (59%), Gaps = 29/272 (10%)
 Frame = -2

Query: 913  ISENQYAVICSEKQAKVMSLPTQSCAYKQNITETSFVLRGDIVALSNSVCLACFCANGHI 972
            ++E QY VI SEKQ KV  +  Q C  +  ++E  F ++ + + + +  CLA + +NGH+
Sbjct: 937  LTERQYIVIASEKQTKVFDVANQCCINRIQLSEMDFAVKAETITMKDGSCLATYLSNGHL 758

Query: 973  MTFSLPSLRPLLDVYYLPLTNM-----------------------------RIARTFCFA 1003
            M  SLPSL+ LLD  +LPL  +                             +I++ FCF+
Sbjct: 757  MVHSLPSLKLLLDTDFLPLMELSFQTKCKQGIVDPMLSIWGQQIIVHEDTTQISKIFCFS 578

Query: 1004 NNGQALYLVSPTEIQRLTYSQETCENLQEMLGELFTPVETPEAPNRGFFKGLFGGGAQSL 1063
            + G  LY+ SPTEIQ+ T S E C+ + EM+GEL+T  E PE P   F KGLFGGGA+ L
Sbjct: 577  HKGHGLYMASPTEIQKFTISSEFCQFILEMMGELYTVHEMPEQPKESFXKGLFGGGAKLL 398

Query: 1064 DREELFGESSSGKASRSLAQHIPGPGGIEGVKGAASGVVGELARARLALDERGQKLSDLE 1123
            DREELFGE  SGKA+RS A+HIPGP  ++ +    S    E++RA     ERG+KL+ LE
Sbjct: 397  DREELFGE-QSGKANRSTARHIPGP-TLDQLGQRTSTAASEISRAHQLAMERGEKLNLLE 224

Query: 1124 ERTAAMMSSADSFSKHAHEMMLKYKDKKWYQF 1155
            ER   M ++A  FS  AH+++LKYKDKKWYQ 
Sbjct: 223  ERAERMANTAQDFSGTAHQLLLKYKDKKWYQL 128
>30464
          Length = 977

 Score =  180 bits (456), Expect = 3e-45,   Method: Compositional matrix adjust.
 Identities = 84/156 (53%), Positives = 112/156 (71%), Gaps = 2/156 (1%)
 Frame = -3

Query: 374 LVLIDLAQNGYPIFENPYPLSIHESPVTCCEYFADCPVDLIPALYSVGARQKRQGYSKKE 433
           LV++DL   GYP FENPYP+ +HESPVT C+Y+A+CP DL+PA YSVG+RQK+ G+S+K 
Sbjct: 975 LVVVDLTTPGYPCFENPYPMDLHESPVTACQYYANCPTDLVPAFYSVGSRQKKTGFSEKA 796

Query: 434 WPINGGNWGLGAQSYPEIIITGHADGSVKFWDASAITLQVLYKLKTS-KVFEKSRNKDDR 492
           WPI GG WG    SYPEIIITGHADGS+KFWDAS+++LQ   ++K   K+FEK +   D 
Sbjct: 795 WPIKGGQWGTTTVSYPEIIITGHADGSLKFWDASSVSLQNFVQIKKRPKIFEKPQRSGDS 616

Query: 493 QNTDIVDEDPYAIQI-ISWCPESRMLCIAGVSAHVI 527
           Q     D+DP+AIQ  +     S  +C+ G+S + +
Sbjct: 615 Q-----DDDPFAIQKHLPVS*VSHAVCVRGLSRYAL 523

 Score =  149 bits (375), Expect = 9e-36,   Method: Compositional matrix adjust.
 Identities = 101/274 (36%), Positives = 145/274 (52%), Gaps = 2/274 (0%)
 Frame = -1

Query: 422 ARQKRQGYSKKEWPINGGNWGLGA-QSYPEIIITGHADGSVKFWDASAITLQVLYKLKTS 480
           A  KR G S++    +GG   L   +S   +++ G +   +          ++LYKLK  
Sbjct: 812 ASVKRPGLSREA---SGGRQQLAILKSSSPVMLMGRSSSGMHL----QFHFKILYKLKNG 654

Query: 481 KVFEKSRNKDDRQNTDIVDEDPYAIQIISWCPESRMLCIAGVSAHVIIYRFSKQEVLTEV 540
           +  +  R+   R     +   P     I  CPESRMLC++G S HV+++RF KQE+  EV
Sbjct: 653 Q--KSLRSLSGRGTVRTMIHLPSXN--IFLCPESRMLCVSGAS-HVMLFRFCKQELTLEV 489

Query: 541 IPMLEVRLLYEIND-VDTPEGEQPPPLSTPVGXXXXXXXXXXXXXXXXXXXXDGLRDNVP 599
              LE  ++YEI D +D+PE E P  L  P                          + + 
Sbjct: 488 -SCLEFSIVYEIFDELDSPEFEYPT-LPRPTLAVAAQHSSSMGSYSSSTSDNAKASEGMT 315

Query: 600 CLKVKNSPLKQSPGYQTELVIQLVWVGGEPPQQITSLALNSSYGLVVFGNCNGIAMVDYL 659
            +KV+    K + GYQ +LV  L +V GEPP  IT ++LNS+YGL+ FGN +G+A+VD++
Sbjct: 314 AVKVRGGARKWAAGYQADLVCVLCYVEGEPPGNITVMSLNSTYGLLAFGNESGLAIVDFI 135

Query: 660 QKAVLLNLSTIELYGSNDPYRREPRSPRKSRQPS 693
           QK  LLNL T +LYGS DPY+R PRSPR  +  S
Sbjct: 134 QKTCLLNLGTPDLYGSMDPYQRAPRSPRSKKSQS 33
>08872
          Length = 466

 Score =  122 bits (305), Expect = 1e-27,   Method: Compositional matrix adjust.
 Identities = 66/145 (45%), Positives = 89/145 (61%), Gaps = 7/145 (4%)
 Frame = -2

Query: 45  EHFQLCKTVRHGFPYQPSALAFDPVQKILAVGTQTGALRLFGRPGVECYCQHDSGAAVIQ 104
           E F   K   HGFP +PSALAFDP  K++A+GT++GA++++G PGVE    H    +V  
Sbjct: 465 ELFDFQKCADHGFPSKPSALAFDPKLKLIAIGTKSGAVKVYGAPGVEFSGVHKEDVSVTN 286

Query: 105 LQFLINEGALVSALADDTLHLW--NLRQKRPAVLHSLKFCRE-----RVTFCHLPFQSKW 157
           L FL  EG LVS  +D+TLHLW  NLR  +  +    +F  E      V+ C L   S+ 
Sbjct: 285 LFFLPEEGRLVSVCSDNTLHLWEINLRSGQSVIEEVKEFSMENNKMKNVSTCCLTADSQN 106

Query: 158 LYVGTERGNIHIVNVESFTLSGYVI 182
           L +GTE GNIHI+N+ SFTL+  +I
Sbjct: 105 LLLGTEGGNIHILNIASFTLADQII 31
>37988
          Length = 353

 Score = 47.0 bits (110), Expect(2) = 1e-06,   Method: Composition-based stats.
 Identities = 20/29 (68%), Positives = 26/29 (89%)
 Frame = +1

Query: 924 EKQAKVMSLPTQSCAYKQNITETSFVLRG 952
           +KQA+V+SLP+Q+CAYK  ITETSFV+R 
Sbjct: 262 KKQARVVSLPSQTCAYKVKITETSFVVRA 348

 Score = 24.6 bits (52), Expect(2) = 1e-06,   Method: Compositional matrix adjust.
 Identities = 8/15 (53%), Positives = 13/15 (86%)
 Frame = +3

Query: 911 QEISENQYAVICSEK 925
           QE+++ Q+ +ICSEK
Sbjct: 222 QELTDRQFVIICSEK 266
>11187
          Length = 1232

 Score = 44.7 bits (104), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 35/123 (28%), Positives = 58/123 (47%), Gaps = 10/123 (8%)
 Frame = +2

Query: 915  ENQYAV-ICSEKQAKVMSLPTQSCAYKQNIT--ETSFVLRGDIVAL-SNSVC------LA 964
            E Q++V ICSE+Q K  +LP     +K  +T  + S + R   V   SNS        + 
Sbjct: 185  EGQHSVVICSEEQLKAFTLPAMKPLWKTKVTAVDGSRLRRIAFVNFRSNSGDNYSEHDIV 364

Query: 965  CFCANGHIMTFSLPSLRPLLDVYYLPLTNMRIARTFCFANNGQALYLVSPTEIQRLTYSQ 1024
               + G ++ +S+ SLR  L    +   ++    +F F   GQ  +L SP+E   ++ S 
Sbjct: 365  ALNSQGELVVYSVKSLRCQLRSAAVRKEDINGMASFVFTKTGQGYFLQSPSEFGHVSLST 544

Query: 1025 ETC 1027
             +C
Sbjct: 545  SSC 553
>01768
          Length = 1424

 Score = 42.4 bits (98), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 47/181 (25%), Positives = 75/181 (41%), Gaps = 13/181 (7%)
 Frame = +3

Query: 63  ALAFDPVQK-ILAVGTQTGALRLFGRPGVECYCQHDSGAA-----VIQLQFLINEGALVS 116
           A+ + P  K  L  G  TGA+ +  +P    +    S  A     V  +Q+  NEG + +
Sbjct: 714 AIDWSPAAKGWLVTGDCTGAIYI-SQPSSSGWTTEKSSYAAHTDSVEDVQWSPNEGNVFA 890

Query: 117 ALA-DDTLHLWNLRQKRPAVLHSLKF----CRERVTFCHLPFQSKWLYVGTERGNIHIVN 171
           + + D TL +WN +QK P+  + L       R+       P +   L  G + G I I +
Sbjct: 891 SCSVDRTLRIWNTQQK-PSKANVLTVPEAHSRDINVINWNPIEKHLLASGGDDGIIKIWD 1067

Query: 172 VESFTLSGYVIMWNKAI--ELSSKAHPGPVVHISDNPMDEGKLLIGFESGTVVLWDLKSK 229
           +  F         NK +  + S K H  PV  +  NP D   L    E   + +WD   +
Sbjct: 1068LRMFR--------NKPVSAQASFKLHSQPVTSLEWNPQDSSVLAASGEDDQITIWDFSVE 1223

Query: 230 K 230
           +
Sbjct: 1224R 1226
>03387
          Length = 1891

 Score = 40.4 bits (93), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 32/109 (29%), Positives = 45/109 (41%), Gaps = 12/109 (11%)
 Frame = +1

Query: 189 ELSSKAHPGPVVHISDNPMDEGKLLIGFESGTVVLWDLKSKKADYRYT--------YDEA 240
           EL  K H      +S NP   G LL   +  T+ LWD+ S + + R          +   
Sbjct: 340 ELRLKGHQKEGYGLSWNPNLNGHLLSASDDHTICLWDINSTQRESRVVDAHTIFTGHTSV 519

Query: 241 IHSVAWH--HEGKQFICSHSDGTLTIWNVRS--PAKPVQTITPHGKQLK 285
           +  VAWH  HE   F     D  L IW+ RS   +KP   +  H  ++ 
Sbjct: 520 VEDVAWHLLHES-LFGSVADDQKLMIWDTRSNTTSKPSHVVDAHTAEVN 663
>01462
          Length = 995

 Score = 37.7 bits (86), Expect = 0.028,   Method: Compositional matrix adjust.
 Identities = 18/82 (21%), Positives = 41/82 (50%), Gaps = 1/82 (1%)
 Frame = +2

Query: 204 DNPMDEGKLLIGFESGTVVLWDLKSKK-ADYRYTYDEAIHSVAWHHEGKQFICSHSDGTL 262
           D  M   +L  G     + +WD+++ +  +    + + IH V   ++ ++ + +  DGT+
Sbjct: 218 DEKMGTRRLYAGAGDRKIHVWDIEAGQYLNAMEGHKDYIHKVVMKNDAQECVSASEDGTV 397

Query: 263 TIWNVRSPAKPVQTITPHGKQL 284
            +W++RS  + V  + P   +L
Sbjct: 398 RMWDIRSSTETVHCLEPSKNEL 463
>20662
          Length = 1220

 Score = 33.5 bits (75), Expect = 0.58,   Method: Compositional matrix adjust.
 Identities = 15/65 (23%), Positives = 34/65 (52%), Gaps = 5/65 (7%)
 Frame = +2

Query: 207 MDEGKLLIGFESGTVVLWDLKSKKADYRY-----TYDEAIHSVAWHHEGKQFICSHSDGT 261
           +D  K+L+G ++G V LW+L+ +   +        +D+   SV+ + +   ++ +  D  
Sbjct: 278 VDSHKVLVGLDTGGVALWELQDEDKMFSMLSSACEHDDMTASVSINSDXSHYLSASYDHG 457

Query: 262 LTIWN 266
           + +WN
Sbjct: 458 IKVWN 472
>15337
          Length = 860

 Score = 33.1 bits (74), Expect = 0.63,   Method: Compositional matrix adjust.
 Identities = 30/114 (26%), Positives = 46/114 (40%), Gaps = 11/114 (9%)
 Frame = -1

Query: 30  PPGNREPEIQETLQSEHFQL--CKTVRHGFPYQP--------SALAFDPVQKILAVGTQT 79
           P G   P  Q   Q E + +  CKT     P           S  AF P  + LAV  Q 
Sbjct: 443 PCGQTPPNYQPFKQGEGYSVFTCKTKSTRNPLYRWVVGTGAISEFAFSPCSRYLAVVGQD 264

Query: 80  GALRLFGRPGVECYCQHDS-GAAVIQLQFLINEGALVSALADDTLHLWNLRQKR 132
           G LR+F    +E      S    ++ + +  +   +V+   DD + +W+  +KR
Sbjct: 263 GHLRVFNYNSMELIGTMKSYFGGLLCVCWSPDGKYIVTGGEDDLVTVWSFHEKR 102
>02948
          Length = 1207

 Score = 33.1 bits (74), Expect = 0.66,   Method: Compositional matrix adjust.
 Identities = 25/93 (26%), Positives = 41/93 (44%), Gaps = 6/93 (6%)
 Frame = -2

Query: 178 SGYVIMW-----NKAIELSSKAHPGPVVHISDNPMDEGK-LLIGFESGTVVLWDLKSKKA 231
           SG +  W     +K +   S  H  PV  ++  P  EG  LL G    T+V W + S+  
Sbjct: 693 SGKITFWWNFDQDKTVLSVSHWHSLPVTCLAFTP--EGSCLLSGGHECTLVRWQMNSEHK 520

Query: 232 DYRYTYDEAIHSVAWHHEGKQFICSHSDGTLTI 264
           ++       +H++    +G  F+  HSD  L +
Sbjct: 519 EFLPRLGAPLHNIVVSPDGVFFVTGHSDNVLQV 421
>21105
          Length = 650

 Score = 33.1 bits (74), Expect = 0.70,   Method: Composition-based stats.
 Identities = 23/68 (33%), Positives = 36/68 (52%), Gaps = 5/68 (7%)
 Frame = +1

Query: 194 AHPGPVVHISDNPMDEGKLLIGFESGTVVLWDLKSKK-----ADYRYTYDEAIHSVAWHH 248
           AH   V  ++ +P +   LL G    ++ LW+L SK        +R  +DE+IH VA+H 
Sbjct: 184 AHLDSVTSLAVDP-NGLYLLSGSHDCSIRLWNLDSKTCVQEITSHRKKFDESIHDVAFHP 360

Query: 249 EGKQFICS 256
           + K +I S
Sbjct: 361 Q-KPYIAS 381
>00561
          Length = 1003

 Score = 32.7 bits (73), Expect = 0.83,   Method: Compositional matrix adjust.
 Identities = 19/66 (28%), Positives = 32/66 (48%), Gaps = 1/66 (1%)
 Frame = -3

Query: 208 DEGKLLIGFESGTVVLWDLKSKKADYRYT-YDEAIHSVAWHHEGKQFICSHSDGTLTIWN 266
           D    L G    T+ LWDL + K   R+  + + + SVA+  + +Q +    D T+ +WN
Sbjct: 833 DGNYALSGSWDQTLRLWDLAAGKTTRRFEGHTKDVLSVAFSADNRQIVSGSRDKTIKLWN 654

Query: 267 VRSPAK 272
             +  K
Sbjct: 653 TLAECK 636
>01598
          Length = 1545

 Score = 32.3 bits (72), Expect = 1.00,   Method: Compositional matrix adjust.
 Identities = 27/118 (22%), Positives = 57/118 (48%), Gaps = 9/118 (7%)
 Frame = +1

Query: 174 SFTLSGYVIMWN-KAIE-LSSKAHPGPVVH-ISDNPMDEGKLLIGFESGTVVLWDLKSKK 230
           +F     V++W+ + +E ++S A  G  V+ +  +P+D G++ +G     +  W++ +K 
Sbjct: 430 TFAQDRQVVLWDLETMEAVASMATLGGHVYCVRTSPIDPGRVAVGVGDSMIRTWNMSNKT 609

Query: 231 ADYRYT-----YDEAIHSVAWHHEGKQFI-CSHSDGTLTIWNVRSPAKPVQTITPHGK 282
             Y  T         + +VAWH   + ++     DG + +++V S   P  + T H +
Sbjct: 610 NPYDVTTLWQGIKSKVTAVAWHPTKEGWLGFGTDDGRIGVFDVLSHKMPTLSNTFHHR 783
>13278
          Length = 870

 Score = 32.3 bits (72), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 21/75 (28%), Positives = 38/75 (50%), Gaps = 1/75 (1%)
 Frame = +1

Query: 195 HPGPVVHISDNPMDEGKLLI-GFESGTVVLWDLKSKKADYRYTYDEAIHSVAWHHEGKQF 253
           H  PV  ++ +P  +GK L  G     V +W++++    + Y     I  V W+H G + 
Sbjct: 199 HQEPVYSVAFSP--DGKYLASGSFDKCVHIWNVQTGSLVHSYKGTGGIFEVCWNHRGDKV 372

Query: 254 ICSHSDGTLTIWNVR 268
             S SDG++ + ++R
Sbjct: 373 GASASDGSVFVLDLR 417
>16746
          Length = 340

 Score = 31.6 bits (70), Expect = 2.2,   Method: Composition-based stats.
 Identities = 15/34 (44%), Positives = 22/34 (64%), Gaps = 3/34 (8%)
 Frame = +1

Query: 1114 ERGQKLSDLEERTAAMMSSADSF---SKHAHEMM 1144
            ERG +L DL++++ ++ SSAD F   SK  H  M
Sbjct: 40   ERGDRLEDLQDKSDSLSSSADMFRSRSKSLHHNM 141
>36468
          Length = 696

 Score = 31.2 bits (69), Expect = 2.6,   Method: Compositional matrix adjust.
 Identities = 17/59 (28%), Positives = 28/59 (47%)
 Frame = +2

Query: 475 YKLKTSKVFEKSRNKDDRQNTDIVDEDPYAIQIISWCPESRMLCIAGVSAHVIIYRFSK 533
           Y L  S+  E S + D RQN  + D+D   I +I     +    + G+ A+VI   + +
Sbjct: 239 YDLDLSQSHESSDDADRRQNARLTDDDDRGIDVIPLYCVALGSVVVGLLAYVIFVHYRR 415
>29419
          Length = 511

 Score = 30.8 bits (68), Expect = 2.9,   Method: Compositional matrix adjust.
 Identities = 21/69 (30%), Positives = 33/69 (47%), Gaps = 3/69 (4%)
 Frame = +2

Query: 65  AFDPVQKILAVGTQTGALR---LFGRPGVECYCQHDSGAAVIQLQFLINEGALVSALADD 121
           A+  + K+   G+Q  A+R   + G  G +      S     QL+ L+ EG L+    D+
Sbjct: 191 AYSSMSKMPPNGSQRKAVRKVSVSGGGGRDWGVMEMSDTLRAQLEELMMEGDLLEVTLDE 370

Query: 122 TLHLWNLRQ 130
           T H+W L Q
Sbjct: 371 TQHIWKLLQ 397
>02090
          Length = 1841

 Score = 30.8 bits (68), Expect = 3.0,   Method: Compositional matrix adjust.
 Identities = 19/73 (26%), Positives = 33/73 (45%)
 Frame = -3

Query: 54   RHGFPYQPSALAFDPVQKILAVGTQTGALRLFGRPGVECYCQHDSGAAVIQLQFLINEGA 113
            +H F  Q  +L + P  + LAVG ++  + +      + Y  H   + V+ L+F      
Sbjct: 1389 QHDFSSQIFSLGYCPTGEWLAVGMESSNVEVLHHSKPDKYQLHLHESCVLSLKFAYCGKW 1210

Query: 114  LVSALADDTLHLW 126
             VS   D+ L+ W
Sbjct: 1209 FVSTGKDNLLNAW 1171
>12841
          Length = 1364

 Score = 30.8 bits (68), Expect = 3.4,   Method: Compositional matrix adjust.
 Identities = 30/123 (24%), Positives = 49/123 (39%), Gaps = 3/123 (2%)
 Frame = +1

Query: 160  VGTERGNIHIVNVESFTLSGYVIMWNKAIELSSKAHPGPVVHISDNPMDEGKLLIGFESG 219
             GTE G IH  +            +N+    +   H  PV HI  +P      L      
Sbjct: 970  AGTEEGYIHKCSCS----------YNEQYLETYSGHTAPVYHIRWSPFVSDIFLSCSADW 1119

Query: 220  TVVLWDL-KSKKADYRYTYDEAIHSVAWH-HEGKQFICSHSDGTLTIWNV-RSPAKPVQT 276
            ++ LW   ++      ++  + +H V W       F C H +G + +W++ +S    V T
Sbjct: 1120 SIRLWHQDRTTPILTFHSSTKTVHDVCWSPRSSTVFACVH-EGAVEVWDLAQSTLDAVIT 1296

Query: 277  ITP 279
            ITP
Sbjct: 1297 ITP 1305
>16996
          Length = 1194

 Score = 30.0 bits (66), Expect = 6.0,   Method: Compositional matrix adjust.
 Identities = 20/60 (33%), Positives = 31/60 (51%), Gaps = 1/60 (1%)
 Frame = -3

Query: 593 GLRDNVPCLKVKNSPLKQ-SPGYQTELVIQLVWVGGEPPQQITSLALNSSYGLVVFGNCN 651
           G+R    CLK+K S  +Q S  +    VI+ ++   +P + I SL+L  S G  +  N N
Sbjct: 811 GIRQTAQCLKMKLSXTRQ*SXVHSRRKVIKKLFKPSQPQRGICSLSLYFSLGKQMLHNLN 632
>08948
          Length = 1476

 Score = 30.0 bits (66), Expect = 6.4,   Method: Compositional matrix adjust.
 Identities = 11/26 (42%), Positives = 16/26 (61%)
 Frame = +1

Query: 995  RIARTFCFANNGQALYLVSPTEIQRL 1020
            R+A TF   N+GQ LY+  P  + +L
Sbjct: 499  RVAHTFLSVNHGQGLYITKPYSVPKL 576
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|13385320|ref|NP_080118.1| vacuolar protein sorting 28
[Mus musculus]
         (221 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

15299                                                                 310   2e-85
25948                                                                  28   2.1  
17296                                                                  27   5.2  
>15299
          Length = 1895

 Score =  310 bits (795), Expect = 2e-85,   Method: Compositional matrix adjust.
 Identities = 146/198 (73%), Positives = 171/198 (86%)
 Frame = -3

Query: 23   EVKLYKNAREREKYDNMAELFAVVKTMQALEKAYIKDCVTPNEYTAACSRLLVQYKAAFR 82
            EVKLY+ ARERE  DNMA+L+AV+ T+Q+LEKAYI+D V P EYTA CSRLLVQYKAAF+
Sbjct: 1893 EVKLYRTARERENNDNMADLYAVINTLQSLEKAYIRDAVLPKEYTATCSRLLVQYKAAFK 1714

Query: 83   QVQGSEISSIDEFCRKFRLDCPLAMERIKEDRPITIKDDKGNLNRCIADVVSLFITVMDK 142
            QVQ S+ +++++F +K+RLDCP A+ERIKE RPITIKDDKGN ++CIAD+VSLFIT+MDK
Sbjct: 1713 QVQ-SDFTTVEDFMKKYRLDCPAALERIKEGRPITIKDDKGNTSKCIADIVSLFITIMDK 1537

Query: 143  LRLEIRAMDEIQPDLRELMETMHRMSHLPPDFEGRQTVSQWLQTLSGMSASDELDDSQVR 202
            LRLEIRAMDEIQPDLRELMETM+RMS LP  FEGR  V +WL TL  M AS+ELDD QVR
Sbjct: 1536 LRLEIRAMDEIQPDLRELMETMNRMSILPAHFEGRSKVQKWLDTLGSMQASEELDDGQVR 1357

Query: 203  QMLFDLESAYNAFNRFLH 220
            QMLFDLES+YNAFN  LH
Sbjct: 1356 QMLFDLESSYNAFNNVLH 1303
>25948
          Length = 417

 Score = 28.5 bits (62), Expect = 2.1,   Method: Compositional matrix adjust.
 Identities = 12/33 (36%), Positives = 21/33 (63%)
 Frame = +2

Query: 181 SQWLQTLSGMSASDELDDSQVRQMLFDLESAYN 213
           S W+ +LS    +D  DD++V+Q + + +S YN
Sbjct: 236 SPWVASLSEERGTDVCDDAEVQQAIREYQSNYN 334
>17296
          Length = 487

 Score = 27.3 bits (59), Expect = 5.2,   Method: Compositional matrix adjust.
 Identities = 16/42 (38%), Positives = 26/42 (61%), Gaps = 3/42 (7%)
 Frame = +1

Query: 137 ITVMDK--LRLEIRAMDEI-QPDLRELMETMHRMSHLPPDFE 175
           ++VMD   +RL+ R +  +  PDLR  ++T+  + HLPP  E
Sbjct: 298 VSVMDSPFVRLDERKLAPMTPPDLRATLDTLDPLHHLPPRPE 423
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|148747558|ref|NP_035693.3| peroxiredoxin 2 [Mus
musculus]
         (198 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

10721                                                                 310   2e-85
09130                                                                 290   2e-79
09123                                                                  72   1e-13
08530                                                                  27   4.2  
>10721
          Length = 1542

 Score =  310 bits (795), Expect = 2e-85,   Method: Compositional matrix adjust.
 Identities = 145/195 (74%), Positives = 163/195 (83%)
 Frame = -2

Query: 4    GNAQIGKSAPDFTATAVVDGAFKEIKLSDYRGKYVVLFFYPLDFTFVCPTEIIAFSDHAE 63
            G   I K AP+F+  AVVDG FK +KLSDY+GKYVVLFFYPLDFTFVCPTEIIAFSD  E
Sbjct: 1463 GQLAIQKPAPEFSVQAVVDGDFKTVKLSDYKGKYVVLFFYPLDFTFVCPTEIIAFSDRVE 1284

Query: 64   DFRKLGCEVLGVSVDSQFTHLAWINTPRKEGGLGPLNIPLLADVTKSLSQNYGVLKNDEG 123
            +FR + CEVL  S DS F+HLAW+NTPRK+GGLG + IPLLAD T  LS+ YG LK DEG
Sbjct: 1283 EFRSIQCEVLAASTDSVFSHLAWVNTPRKQGGLGNMKIPLLADKTLELSRMYGCLKEDEG 1104

Query: 124  IAYRGLFIIDAKGVLRQITVNDLPVGRSVDEALRLVQAFQYTDEHGEVCPAGWKPGSDTI 183
            IAYR L+IID KG LRQIT+NDLPVGRSVDE LRLVQAFQ+TD+HGEVCPAGWKPG+DTI
Sbjct: 1103 IAYRALYIIDDKGTLRQITMNDLPVGRSVDETLRLVQAFQFTDKHGEVCPAGWKPGADTI 924

Query: 184  KPNVDDSKEYFSKHN 198
            KP+V DSK +FSK N
Sbjct: 923  KPSVKDSKTFFSKAN 879
>09130
          Length = 1000

 Score =  290 bits (743), Expect = 2e-79,   Method: Compositional matrix adjust.
 Identities = 135/194 (69%), Positives = 157/194 (80%)
 Frame = +1

Query: 5   NAQIGKSAPDFTATAVVDGAFKEIKLSDYRGKYVVLFFYPLDFTFVCPTEIIAFSDHAED 64
            A I K APD+  TAV+DG FK+IKLSD+RGKY+V FFYPLDFTFVCPTEI+AFSD+   
Sbjct: 190 QAVISKPAPDWNGTAVIDGEFKDIKLSDFRGKYLVFFFYPLDFTFVCPTEIVAFSDNVGK 369

Query: 65  FRKLGCEVLGVSVDSQFTHLAWINTPRKEGGLGPLNIPLLADVTKSLSQNYGVLKNDEGI 124
           F+ +  EV+  SVDSQFTHLAWINTPR +GGLGPL IPLL+D+T  +++ YGV   D G 
Sbjct: 370 FKSINTEVVACSVDSQFTHLAWINTPRNQGGLGPLKIPLLSDITHDIAKAYGVYLQDLGH 549

Query: 125 AYRGLFIIDAKGVLRQITVNDLPVGRSVDEALRLVQAFQYTDEHGEVCPAGWKPGSDTIK 184
           + RGLFIID KG+LRQIT+NDLPVGRSVDE LRLVQAFQYTD HGEVCP GWKPGSDTI 
Sbjct: 550 SLRGLFIIDPKGILRQITMNDLPVGRSVDETLRLVQAFQYTDAHGEVCPVGWKPGSDTII 729

Query: 185 PNVDDSKEYFSKHN 198
           P+   SK+YF+K  
Sbjct: 730 PDPKQSKKYFNKQK 771
>09123
          Length = 1944

 Score = 72.4 bits (176), Expect = 1e-13,   Method: Compositional matrix adjust.
 Identities = 49/172 (28%), Positives = 82/172 (47%), Gaps = 12/172 (6%)
 Frame = -3

Query: 37   YVVLFFYPLDFTFVCPTEIIAFSDHAEDFRKLGCEVLGVSVDSQFTHLAWINTPRKEGGL 96
            + +LF +P D+T VC TE+    +   +F K  C+V  +S D   +H  W    +K  G+
Sbjct: 1606 WAILFSHPADYTPVCTTELGRVLNLIGEFEKRKCKVFALSCDGPESHKGWAKDVQKYAGV 1427

Query: 97   ---GPLNIPLLADVTKSLSQNYGVL----KNDEGIAY--RGLFIIDAKGVLRQITVNDLP 147
                    P++AD  + L+   G++    K  +G+    R +FII     L+   +    
Sbjct: 1426 DTDTKFPYPIIADEKRDLAVQLGMVDPAEKTKDGLPLTCRAVFIIGPDKKLKLSLLYPAT 1247

Query: 148  VGRSVDEALRLVQAFQYTDEHGEVCPAGWKPGSDT-IKPNVDD--SKEYFSK 196
             GR+ DE LR++ + Q T       P  W+PG    + P+V D  +K+ F+K
Sbjct: 1246 TGRNFDEILRVLDSLQLTATKKVATPENWQPGGKCMVIPSVSDEEAKKLFTK 1091
>08530
          Length = 1100

 Score = 27.3 bits (59), Expect = 4.2,   Method: Compositional matrix adjust.
 Identities = 12/39 (30%), Positives = 19/39 (48%)
 Frame = +2

Query: 38  VVLFFYPLDFTFVCPTEIIAFSDHAEDFRKLGCEVLGVS 76
           ++LF Y L    +CP   +  + H     K+ C+V  VS
Sbjct: 95  IILFIYLLSTALICPY--LWLAGHKATINKINCQVQVVS 205
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31981722|ref|NP_071705.2| heat shock protein 5 [Mus
musculus]
         (655 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

30255                                                                 265   3e-85
21024                                                                 265   6e-71
37715                                                                 167   1e-67
26390                                                                 228   2e-61
27378                                                                 137   1e-32
31218                                                                 126   3e-29
24750                                                                 110   2e-24
20979                                                                  86   7e-17
09881                                                                  84   2e-16
12271                                                                  65   1e-10
06909                                                                  56   3e-10
13684                                                                  51   1e-06
13300                                                                  49   5e-06
03996                                                                  47   3e-05
34036                                                                  33   0.51 
36653                                                                  30   2.3  
>30255
          Length = 1761

 Score =  265 bits (677), Expect(2) = 3e-85,   Method: Compositional matrix adjust.
 Identities = 131/197 (66%), Positives = 156/197 (79%), Gaps = 2/197 (1%)
 Frame = -1

Query: 354  KSDIDEIVLVGGSTRIPKIQQLVKEFFNGKEPSRGINPDEXXXXXXXXXXXXLSGD--QD 411
            K  I EIVLVGGSTRIPKIQ+L+++FFNGKE  + INPDE            L GD  ++
Sbjct: 1644 KPGIHEIVLVGGSTRIPKIQKLLQDFFNGKELCKSINPDEAVAYGACVQAAILHGDKSEE 1465

Query: 412  TGDLVLLDVCPLTLGIETVGGVMTKLIPRNTVVPTKKSQIFSTASDNQPTVTIKVYEGER 471
              DL+LLDV PL++GIET GGVMT LI RNT +PTK++Q F+T SDNQP V I+VYEGER
Sbjct: 1464 VQDLLLLDVAPLSMGIETAGGVMTALIKRNTTIPTKQTQTFTTYSDNQPGVLIQVYEGER 1285

Query: 472  PLTKDNHLLGTFDLTGIPPAPRGVPQIEVTFEIDVNGIIRVTAEDKGTGNKNKITITNDQ 531
             +T+DN+LLG F+LTGIPPAPRGVPQIEVTF+ID NGI+ V+A DK TG +NKITITND+
Sbjct: 1284 AMTRDNNLLGKFELTGIPPAPRGVPQIEVTFDIDANGILNVSAADKSTGKENKITITNDK 1105

Query: 532  NRLTPEEIERMVNDAEK 548
             RL+ EEIERMVNDAEK
Sbjct: 1104 GRLSKEEIERMVNDAEK 1054

 Score = 69.3 bits (168), Expect(2) = 3e-85,   Method: Compositional matrix adjust.
 Identities = 35/81 (43%), Positives = 56/81 (69%)
 Frame = -3

Query: 559  RIDTRNELESYAYSLKNQIGDKEKLGGKLSSEDKETMEKAVEEKIEWLESHQDADIEDFK 618
            RI ++N LESYA+ +K+ I D EK+  K+  EDK+T+     E I WL+++Q A+ +++ 
Sbjct: 1024 RISSKNSLESYAFHMKSTIED-EKIKDKIGEEDKKTIVDKCNEVISWLDANQTAEKDEYD 848

Query: 619  AKKKELEEIVQPIISKLYGSG 639
             K+KELE++  PII+KLY + 
Sbjct: 847  DKQKELEKVCNPIITKLYQAS 785
>21024
          Length = 3220

 Score =  265 bits (676), Expect = 6e-71,   Method: Compositional matrix adjust.
 Identities = 171/448 (38%), Positives = 263/448 (58%), Gaps = 14/448 (3%)
 Frame = +1

Query: 193  GLNVMRIINEPTAAAIA--YGLDKREGEKNILVFDLGGGTFDVSLLTIDNGVFEV-VATN 249
            G NV+R+INEPTAAA+A  +G   R  +  +          DV  L + +    V    N
Sbjct: 727  G*NVLRVINEPTAAALALWHGQV*R*SDSGV*FR-----RRDV*HLYLGDPEGSV*SQIN 891

Query: 250  GDTHLGGEDFDQRVMEHFIKLYKKKTGKDVRKD----NRAVQKLRREV---EKAKRALSS 302
               H+ G    +R +      +     +++RK     ++ +Q L R+    +K+K  LSS
Sbjct: 892  QRRHIPG----RRGL--LTTTWSTSWHQNLRKSKD*TSQRIQWLCRDYVRQQKSKIELSS 1053

Query: 303  QHQARIEIESFFEG----EDFSETLTRAKFEELNMDLFRSTMKPVQEVLEDSDLKKSDID 358
              Q  I +          +  +  L+R+KFE L   L + T+ P Q+ L+D+++KKSDI 
Sbjct: 1054 SLQTDINLPYLTMDASGPKHMNLKLSRSKFESLVESLVKRTVGPCQKALQDAEVKKSDIG 1233

Query: 359  EIVLVGGSTRIPKIQQLVKEFFNGKEPSRGINPDEXXXXXXXXXXXXLSGDQDTGDLVLL 418
            E++LVGG +R+PK+Q  V++ F G+ PS+ +NPDE            L+GD    D++LL
Sbjct: 1234 EVILVGGMSRMPKVQSTVQDLF-GRTPSKSVNPDEAVAIGAAIQGGVLAGD--VTDVLLL 1404

Query: 419  DVCPLTLGIETVGGVMTKLIPRNTVVPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNH 478
            DV PL+LGIET+GGV TKLI RNT +PTKKSQ+FSTA+D Q  V IKV++GER +  DN 
Sbjct: 1405 DVTPLSLGIETLGGVFTKLINRNTTIPTKKSQVFSTAADGQTQVEIKVHQGEREMANDNK 1584

Query: 479  LLGTFDLTGIPPAPRGVPQIEVTFEIDVNGIIRVTAEDKGTGNKNKITITNDQNRLTPEE 538
            LLG F L GIPPAPRGVPQ+EVTF+ID NGI+ V+A DKGTG + +I I +    L+ +E
Sbjct: 1585 LLGQFTLVGIPPAPRGVPQVEVTFDIDANGIVNVSARDKGTGKEQQIVIQSS-GGLSKDE 1761

Query: 539  IERMVNDAEKFAEEDKKLKERIDTRNELESYAYSLKNQIGDKEKLGGKLSSEDKETMEKA 598
            IE M+ +AE  AE+D++ KE ++  N+ +S  +  ++++   E+   +L  E+ + + + 
Sbjct: 1762 IENMIKNAEAHAEDDRRKKELVEVLNQADSIIHDTESKM---EEFKDQLPQEECDKLREK 1932

Query: 599  VEEKIEWLESHQDADIEDFKAKKKELEE 626
            + E  + L +  +   E  + +  +L++
Sbjct: 1933 INEVKQLLANKDNEAPEKIREETSDLQQ 2016

 Score =  184 bits (467), Expect = 9e-47,   Method: Compositional matrix adjust.
 Identities = 111/274 (40%), Positives = 165/274 (60%), Gaps = 7/274 (2%)
 Frame = +3

Query: 29  GTVVGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDAAKNQLTSN 88
           G V+GIDLGTT SCV + +  + +++ N +G+R TPS +AFT +GER+ G  AK Q  +N
Sbjct: 246 GHVIGIDLGTTNSCVALMEGKQAKVLENSEGSRTTPSVIAFTKDGERISGMPAKRQAVTN 425

Query: 89  PENTVFDAKRLIGRTWNDPSVQQDIKFLPFKVVEKKT-KPYIQVDIGGGQTKTFAPEEIS 147
            ENT+   KRLIGR + DP VQ+D+K + +K+V+      +++      Q K ++P ++ 
Sbjct: 426 AENTLSATKRLIGRRFEDPEVQKDMKNVSYKIVKASNGDAWVE-----AQGKMYSPSQVG 590

Query: 148 AMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRI---INEPT 204
           A VL KMKETAE+YLG KV +AVVTVPAYFND+QRQATKDAG I+GL  +      +  +
Sbjct: 591 AFVLMKMKETAESYLGSKVNNAVVTVPAYFNDSQRQATKDAGQISGLKCVACDQRTHSCS 770

Query: 205 AAAIAYGLDKREGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATN--GDTHLGGE-DFDQ 261
           +  +A+   K +  + ++  +  G    +S  +      E + +N   +TH   E  FD 
Sbjct: 771 SCFMAWTSLKIK**RCLI*AE--GRLTSLSWRSRR----ECLKSNQPTETHSWEERTFDN 932

Query: 262 RVMEHFIKLYKKKTGKDVRKDNRAVQKLRREVEK 295
            ++      +KK+ G D+ KD  AVQ+LR   EK
Sbjct: 933 YMVNFLASEFKKEQGLDITKDPMAVQRLREAAEK 1034
>37715
          Length = 468

 Score =  167 bits (422), Expect(2) = 1e-67,   Method: Composition-based stats.
 Identities = 82/102 (80%), Positives = 90/102 (88%)
 Frame = -2

Query: 118 FKVVEKKTKPYIQVDIGGGQTKTFAPEEISAMVLTKMKETAEAYLGKKVTHAVVTVPAYF 177
            KV+ K  KP+IQ  + G  TKTFAPEEISAMVL KM++ AEAYLGKK+ +AVVTVPAYF
Sbjct: 458 LKVINKSNKPHIQALVSGA-TKTFAPEEISAMVLGKMRDIAEAYLGKKIDNAVVTVPAYF 282

Query: 178 NDAQRQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKREGEK 219
           NDAQRQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKR+GEK
Sbjct: 281 NDAQRQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKRDGEK 156

 Score =  108 bits (270), Expect(2) = 1e-67,   Method: Composition-based stats.
 Identities = 51/53 (96%), Positives = 53/53 (100%)
 Frame = -1

Query: 219 KNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMEHFIKLY 271
           +NILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVM+HFIKLY
Sbjct: 159 ENILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMDHFIKLY 1
>26390
          Length = 665

 Score =  228 bits (582), Expect(2) = 2e-61,   Method: Compositional matrix adjust.
 Identities = 109/195 (55%), Positives = 146/195 (74%), Gaps = 5/195 (2%)
 Frame = +2

Query: 412 TGDLVLLDVCPLTLGIETVGGVMTKLIPRNTVVPTKKSQIFSTASDNQPTVTIKVYEGER 471
           + D++++DV  L+LGIETVGGVMT LI R T +P +K+++FSTA DNQ +VTI+VYEGER
Sbjct: 8   SNDVLVMDVNALSLGIETVGGVMTTLIARGTTIPARKAKVFSTAQDNQDSVTIQVYEGER 187

Query: 472 PLTKDNHLLGTFDLTGIPPAPRGVPQIEVTFEIDVNGIIRVTAEDKGTGNKNKITITNDQ 531
             TKDNHLLG FDLTGIP APRGVPQIEVTF++D NG+++V+AEDKGTG KN I I    
Sbjct: 188 SRTKDNHLLGRFDLTGIPAAPRGVPQIEVTFQVDANGVMQVSAEDKGTGQKNDIIIQQSG 367

Query: 532 NRLTPEEIERMVNDAEKFAEEDKKLKERIDTRNELESYAYSLKNQIGDKEKLG-----GK 586
           + L+PE++ERMV +A+ FAEED+K +E  ++R  LES AY+ ++Q+ D  K+      G 
Sbjct: 368 SGLSPEDVERMVQEAQDFAEEDRKFRELTESRTGLESLAYTAQHQLQDLHKMXASERPGT 547

Query: 587 LSSEDKETMEKAVEE 601
           LS +D    ++ V E
Sbjct: 548 LSDDDLHXAQEVVRE 592

 Score = 26.2 bits (56), Expect(2) = 2e-61,   Method: Compositional matrix adjust.
 Identities = 9/23 (39%), Positives = 16/23 (69%)
 Frame = +3

Query: 603 IEWLESHQDADIEDFKAKKKELE 625
           I+WLE+H  A +E+   +K +L+
Sbjct: 597 IQWLEAHPSASVEEVDERKSQLQ 665
>27378
          Length = 410

 Score =  137 bits (346), Expect = 1e-32,   Method: Compositional matrix adjust.
 Identities = 64/123 (52%), Positives = 90/123 (73%)
 Frame = -1

Query: 271 YKKKTGKDVRKDNRAVQKLRREVEKAKRALSSQHQARIEIESFFEGEDFSETLTRAKFEE 330
           +K+K  KD+R + RA+++LR   E+AKR LSS  +A IE+++ FEG DF   ++RA+FEE
Sbjct: 407 FKRKYKKDLRSNPRALRRLRTAAERAKRTLSSSTEATIEVDALFEGHDFYTKISRARFEE 228

Query: 331 LNMDLFRSTMKPVQEVLEDSDLKKSDIDEIVLVGGSTRIPKIQQLVKEFFNGKEPSRGIN 390
           L  DLFR T+ PV++ L D+ + K  I +IVLVGGSTRIPK+Q L+++FF GK  +  IN
Sbjct: 227 LCADLFRQTLAPVEKALNDAKMDKQMIHDIVLVGGSTRIPKVQNLLQQFFGGKSLNLSIN 48

Query: 391 PDE 393
           PDE
Sbjct: 47  PDE 39
>31218
          Length = 322

 Score =  126 bits (316), Expect = 3e-29,   Method: Compositional matrix adjust.
 Identities = 61/101 (60%), Positives = 79/101 (78%), Gaps = 1/101 (0%)
 Frame = +2

Query: 251 DTHLGGEDFDQRVMEHFIKLYKKKTGKDVRKDNRAVQKLRREVEKAKRALSSQHQARIEI 310
           DTHLGGEDFDQR++++ +KL K+KTG+DVR D RA+ +LRR  EKAKRALSSQH  ++++
Sbjct: 2   DTHLGGEDFDQRLVDYLVKLIKQKTGRDVRHDTRAMSRLRRSAEKAKRALSSQHSTKVDL 181

Query: 311 ESFFEGEDFSE-TLTRAKFEELNMDLFRSTMKPVQEVLEDS 350
           +      D ++ TLTRAKFEELN DLFRST+  V+  LEDS
Sbjct: 182 DGV--TSDLADLTLTRAKFEELNTDLFRSTLTTVKRALEDS 298
>24750
          Length = 552

 Score =  110 bits (275), Expect = 2e-24,   Method: Compositional matrix adjust.
 Identities = 50/68 (73%), Positives = 61/68 (89%)
 Frame = +1

Query: 464 IKVYEGERPLTKDNHLLGTFDLTGIPPAPRGVPQIEVTFEIDVNGIIRVTAEDKGTGNKN 523
           ++VYEGER +T+DN+LLG F+LTGIPPAPRGVPQIEVTF+ID NGI+ V+A DK TG +N
Sbjct: 157 LQVYEGERAMTRDNNLLGKFELTGIPPAPRGVPQIEVTFDIDANGILNVSAADKSTGKEN 336

Query: 524 KITITNDQ 531
           KITITND+
Sbjct: 337 KITITNDK 360
>20979
          Length = 976

 Score = 85.5 bits (210), Expect = 7e-17,   Method: Compositional matrix adjust.
 Identities = 44/140 (31%), Positives = 82/140 (58%), Gaps = 2/140 (1%)
 Frame = +1

Query: 256 GEDFDQRVMEHFIKLY--KKKTGKDVRKDNRAVQKLRREVEKAKRALSSQHQARIEIESF 313
           G +   R+ +H  K++  +KK    +  + RA+ KL +E E+ K+ LS+    + ++E  
Sbjct: 70  GVEMTLRLRDHLAKVFNGQKKRSFKLEDNPRAMAKLLKEAERVKKVLSANSDHKAQVEGL 249

Query: 314 FEGEDFSETLTRAKFEELNMDLFRSTMKPVQEVLEDSDLKKSDIDEIVLVGGSTRIPKIQ 373
            EGEDF+  ++R  + EL  DL     KP+++ L+ S++   +I EI+L+GG +R+P++Q
Sbjct: 250 VEGEDFAAKVSREDYLELIKDLLARVTKPMEDALKVSEITMPEITEIILMGGGSRVPRVQ 429

Query: 374 QLVKEFFNGKEPSRGINPDE 393
           + + +F    +  + IN DE
Sbjct: 430 EELLKFSGKSDLGKSINTDE 489
>09881
          Length = 600

 Score = 84.3 bits (207), Expect = 2e-16,   Method: Composition-based stats.
 Identities = 41/100 (41%), Positives = 64/100 (64%)
 Frame = +3

Query: 33  GIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDAAKNQLTSNPENT 92
           G+ LGT  +C+ V+K+G+  + AND G+R TP  VAFT   +  +G +AK  + SN +NT
Sbjct: 192 GVHLGTCSACLAVYKDGKTSVAANDAGDRSTPCVVAFTA-CDAEVGASAKQGIVSNVKNT 368

Query: 93  VFDAKRLIGRTWNDPSVQQDIKFLPFKVVEKKTKPYIQVD 132
           V + KR++G T+ DP  Q+ +   P KVV +K +P  +V+
Sbjct: 369 VCNVKRILGLTFEDPVTQEYLASSPVKVVNQKNQPMFEVE 488

 Score = 47.0 bits (110), Expect = 3e-05,   Method: Composition-based stats.
 Identities = 25/50 (50%), Positives = 34/50 (68%)
 Frame = +2

Query: 163 GKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAAAIAYGL 212
           GK +  AV+ VP+ F+D QR A   A + AG  V+R+INE +AAA+AY L
Sbjct: 2   GKGIQDAVLAVPSDFSDKQRAAASAAASKAGFKVLRLINECSAAALAYDL 151
>12271
          Length = 1762

 Score = 65.1 bits (157), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 31/77 (40%), Positives = 48/77 (62%)
 Frame = +2

Query: 317 EDFSETLTRAKFEELNMDLFRSTMKPVQEVLEDSDLKKSDIDEIVLVGGSTRIPKIQQLV 376
           EDFS  +TR K+  L  DL      PVQ+VL  S +  ++I EI+L+GG +R+PKI +++
Sbjct: 38  EDFSCKVTRDKYLHLIQDLLDRVTLPVQQVLTASQITWAEITEIILMGGGSRLPKIHEIL 217

Query: 377 KEFFNGKEPSRGINPDE 393
            ++   KE  + +N DE
Sbjct: 218 LDYSGKKELGKSLNTDE 268
>06909
          Length = 456

 Score = 56.2 bits (134), Expect(2) = 3e-10,   Method: Compositional matrix adjust.
 Identities = 31/74 (41%), Positives = 52/74 (70%), Gaps = 4/74 (5%)
 Frame = -3

Query: 573 LKNQIGDKEKLGGKLSSEDKETMEKAVEEKIEWLESHQDADIEDFKAKKKELEEIVQPII 632
           +K+ I D EK+  K+S+EDK+T+    +E I WL+++Q A+ +++  K+KE+E++  PII
Sbjct: 382 MKSTIED-EKIKDKISTEDKKTILDKCDEVIAWLDANQLAEKDEYDDKQKEIEKVCNPII 206

Query: 633 SKLY----GSGGPP 642
           +KLY    G+GG P
Sbjct: 205 TKLYQAAGGAGGMP 164

 Score = 26.9 bits (58), Expect(2) = 3e-10,   Method: Composition-based stats.
 Identities = 13/23 (56%), Positives = 17/23 (73%)
 Frame = -1

Query: 548 KFAEEDKKLKERIDTRNELESYA 570
           K+ E+D+K K RI  +N LESYA
Sbjct: 456 KYKEDDEKQKSRISAKNSLESYA 388
>13684
          Length = 438

 Score = 51.2 bits (121), Expect = 1e-06,   Method: Composition-based stats.
 Identities = 24/56 (42%), Positives = 36/56 (64%)
 Frame = -3

Query: 33  GIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDAAKNQLTSN 88
           G+ LGT  +C+ V+K+G+  + AND G+R TP  VAFT   +  +G +AK  + SN
Sbjct: 166 GVHLGTCSACLAVYKDGKTSVAANDAGDRSTPCVVAFTA-CDAEVGASAKQGIVSN 2
>13300
          Length = 453

 Score = 49.3 bits (116), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 36/149 (24%), Positives = 73/149 (48%), Gaps = 20/149 (13%)
 Frame = +3

Query: 181 QRQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKREG----EKNILVFDLGGGTFDVSLL 236
           +R+A   A    G+NV++++ +  A A+ YG+ +R+      +  + +D+G  +   +++
Sbjct: 3   ERRAIMTAADXVGINVLQLMTDSAAVALNYGVFRRKNFNTTAQYYMFYDMGATSTVATVV 182

Query: 237 TI------------DNGVFEVVATNGDTHLGGEDFDQRVMEHFIKLY--KKKTGKDVRKD 282
           +              N    +     D  LGG +   R+ +H  K++  +KK    +  +
Sbjct: 183 SYQVVKVKEGTRVESNPQLTIKGVGFDRTLGGLEMTLRLRDHLAKVFNGQKKRSFKLEDN 362

Query: 283 NRAVQKLRREVEKAKRALS--SQHQARIE 309
            RA+ KL +E E+ K+ LS  S H+A++E
Sbjct: 363 PRAMAKLLKEAERVKKVLSANSDHKAQVE 449
>03996
          Length = 1105

 Score = 47.0 bits (110), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 22/64 (34%), Positives = 40/64 (62%)
 Frame = -2

Query: 330  ELNMDLFRSTMKPVQEVLEDSDLKKSDIDEIVLVGGSTRIPKIQQLVKEFFNGKEPSRGI 389
            EL  DL     KP+++ L+ S++   +I EI+L+GG +R+P++Q+ + +F    +  + I
Sbjct: 1056 ELIKDLLARVTKPMEDALKVSEITMPEITEIILMGGGSRVPRVQEELLKFSGKSDLGKSI 877

Query: 390  NPDE 393
            N DE
Sbjct: 876  NTDE 865
>34036
          Length = 363

 Score = 32.7 bits (73), Expect = 0.51,   Method: Composition-based stats.
 Identities = 16/38 (42%), Positives = 26/38 (68%), Gaps = 7/38 (18%)
 Frame = +2

Query: 615 EDFKAKKKELEEIVQPIISKLY----GSGGPP---PTG 645
           +++  K+KE+E++  PII+KLY    G+GG P   P+G
Sbjct: 8   DEYDDKQKEIEKVCNPIITKLYQAAGGAGGMPNFQPSG 121
>36653
          Length = 431

 Score = 30.4 bits (67), Expect = 2.3,   Method: Composition-based stats.
 Identities = 20/62 (32%), Positives = 30/62 (48%)
 Frame = -1

Query: 94  FDAKRLIGRTWNDPSVQQDIKFLPFKVVEKKTKPYIQVDIGGGQTKTFAPEEISAMVLTK 153
           FDAK   GR ++ P+       L  KV +K+ +PY  V +  G   +     ++  VLTK
Sbjct: 212 FDAK---GRRFSLPTSWVSHSCLDSKVRQKRCRPYYNVGMNVGHXNSRITFSVTEFVLTK 42

Query: 154 MK 155
            K
Sbjct: 41  SK 36
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|45597453|ref|NP_036119.1| solute carrier family 27
(fatty acid transporter), member 4 [Mus musculus]
         (643 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

14264                                                                 312   3e-85
26510                                                                  62   5e-10
25481                                                                  43   4e-04
13819                                                                  40   0.003
13327                                                                  39   0.009
20450                                                                  38   0.012
03756                                                                  37   0.031
02626                                                                  32   0.58 
35736                                                                  30   2.3  
16584                                                                  29   4.7  
>14264
          Length = 1790

 Score =  312 bits (799), Expect = 3e-85,   Method: Compositional matrix adjust.
 Identities = 196/472 (41%), Positives = 260/472 (55%), Gaps = 20/472 (4%)
 Frame = -3

Query: 126  GNVVALFMENRNEFVGLWLGMAKLGVEAALINTNLRRDALRHCLDTSKARALIFGS---- 181
             + VAL M+N   F+   LG+ KLGV  ALIN NLR   L H +  ++ +ALI GS    
Sbjct: 1386 ADAVALMMQNEPAFMWTVLGLQKLGVAVALINHNLRAKPLAHAILAAEPKALIVGSGRDV 1207

Query: 182  EMASAICEIHASLEPTLSLFCSGSWEPSTVPVSTEHLDPLLEDAPKHLPSHPDKGFTDKL 241
            + A+   + H    P L     G      VP     LD L+ DA   LP  PD     ++
Sbjct: 1206 QQAAFDIQEHMHGMPVLVQGLCGE----AVPAGMXDLDMLMTDA---LPVRPDPSLRSQM 1048

Query: 242  ------FYIYTSGTTGLPKAAIVVHSRYYRMASLVYYGFRMRPDDIVYDCLPLYHSAGNI 295
                   YIYTSGTTGLPK  +  + +  +M +       +   DIVY  LPLYH +   
Sbjct: 1047 TDDTIGVYIYTSGTTGLPKP-VYYNQKKLKMFTTTAQLLDVTTQDIVYTVLPLYHISAFG 871

Query: 296  VGIGQCLLHGMTVVIRKKFSASRFWDDCIKYNCTIVQYIGELCRYLLNQPPREAESRHKV 355
            VG    L  G T V+++KFSAS+FW DC  YN TIVQYIGEL RYLL QP  E +  HKV
Sbjct: 870  VGFMGLLHQGGTSVLKRKFSASQFWSDCRTYNVTIVQYIGELFRYLLAQPKSELDGVHKV 691

Query: 356  RMALGNGLRQSIWTDFSSRFHIPQVAEFYGATECNCSLGNFDSRVGACGFNSRILSFV-- 413
            R A+GNGLR+ I+ +  +RF I QV EFY ATE    L N  ++ GA G  S  L+F+  
Sbjct: 690  RGAIGNGLRKDIFEEVLTRFKIIQVCEFYAATEGVSGLFNMFNKPGAIGRVSPFLNFLAP 511

Query: 414  YPIRLVRVNEDTMELIRGPDGVCIPCQPGQPG----QLVGRIIQQDPLRRFDGYLNQGAN 469
            YP  +V+ +  T   +R  +G C+  +PG+ G    Q+   I  Q  L  +    ++ AN
Sbjct: 510  YPSVVVKFDYSTAMPVRDKNGRCVKVKPGEIGLFMSQVPDDIQTQGNLTVYKA--SKEAN 337

Query: 470  NKKIANDVFKKGDQAYLTGDVLVMDELGYLYFRDRTGDTFRWKGENVSTTEVEGTLSRLL 529
             KK+  + FK+GD  +  GDV  +D+  ++YF DR GDTFRWKGENVSTTEV   LS   
Sbjct: 336  EKKLVRNAFKEGDLYFNYGDVFYLDKDYFVYFHDRIGDTFRWKGENVSTTEVSNVLSTPD 157

Query: 530  HMADVAVYGVEVPGTEGRAGMAAV----ASPISNCDLESFAQTLKKELPLYA 577
             ++D  VYGV VPG +GRAGMAA+     + ++   L+      + ELP YA
Sbjct: 156  FISDANVYGVTVPGHDGRAGMAALTLNEGTTLAPEQLKZMYTLCQSELPSYA 1
>26510
          Length = 1692

 Score = 62.4 bits (150), Expect = 5e-10,   Method: Compositional matrix adjust.
 Identities = 62/235 (26%), Positives = 93/235 (39%), Gaps = 3/235 (1%)
 Frame = +1

Query: 114 VANFLQARGLASGNVVALFMENRNEFVGLWLGMAKLGVEAALINTNLRRDALRHCLDTSK 173
           VA+ L  RG   G+V+     N  EF  L L  A LGV  +  N       L H L  + 
Sbjct: 328 VASGLHKRGYKKGDVIVTCTVNLPEFSILILAAAYLGVIVSPANPTYTPAELSHMLTHNG 507

Query: 174 ARALIFGSEMASAICEIHASLEPTLSLFCSGSWEPSTVPVSTEHLDPLLEDAPKHLPSHP 233
           A A+    ++   +    A  +P L       +        TE    L+ D  K  P + 
Sbjct: 508 ACAMFTIPQLVPLVQA--AIADPDLPHSVKEVYTFGHAEEGTEFFQALMSDDGKSFPDNI 681

Query: 234 D-KGFTDKLFYIYTSGTTGLPKAAIVVHSRYYRMASLVYYG--FRMRPDDIVYDCLPLYH 290
           D    TD LF  Y+SGTTGLPK  ++ H     +A+++ +      +P+D     LP +H
Sbjct: 682 DINPSTDVLFLPYSSGTTGLPKGVMLSHRNI--VANILQFRELANTQPEDRTLGLLPFFH 855

Query: 291 SAGNIVGIGQCLLHGMTVVIRKKFSASRFWDDCIKYNCTIVQYIGELCRYLLNQP 345
             G        L  G  +V   +F    F         T++Q +  +  +L   P
Sbjct: 856 IYGLTCVQFGTLYDGAELVTVPRFEPELFLKSLHDRKITLLQAVPPVVLFLARHP 1020

 Score = 33.1 bits (74), Expect = 0.34,   Method: Compositional matrix adjust.
 Identities = 24/85 (28%), Positives = 40/85 (47%)
 Frame = +2

Query: 455  DPLRRFDGYLNQGANNKKIANDVFKKGDQAYLTGDVLVMDELGYLYFRDRTGDTFRWKGE 514
            D  ++  GYL+    N++  +D+  + D    TGD+  M E G +   DR  +  ++KG 
Sbjct: 1292 DGPQKMLGYLH----NQQATDDMIDR-DGWLHTGDLGYMREDGMIIIEDRLKELIKYKGF 1456

Query: 515  NVSTTEVEGTLSRLLHMADVAVYGV 539
             V   E+E  L     + D  V G+
Sbjct: 1457 QVPPAELESLLLSHPAVQDAGVIGI 1531
>25481
          Length = 439

 Score = 42.7 bits (99), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 31/109 (28%), Positives = 50/109 (45%), Gaps = 2/109 (1%)
 Frame = -2

Query: 135 NRNEFVGLWLGMAKLGVEAALINTNLRRDALRHCLDTSKARALIFGS--EMASAICEIHA 192
           N   F+   LG+ KLG+ +A +N NLR   L H +  ++ +A I GS  ++  A+ +I  
Sbjct: 321 NEPAFIWTILGLMKLGITSAWLNHNLRLKPLCHSVLATEPKAFIVGSGEDLLQAVVDIRE 142

Query: 193 SLEPTLSLFCSGSWEPSTVPVSTEHLDPLLEDAPKHLPSHPDKGFTDKL 241
            L   + ++      P   P      D L+  A   LP  PD    ++L
Sbjct: 141 ELG-AVPVYVQNV-SPDLTPTGVNSFDGLMTQA---LPVRPDHSVREQL 10
>13819
          Length = 1080

 Score = 39.7 bits (91), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 37/141 (26%), Positives = 61/141 (43%), Gaps = 5/141 (3%)
 Frame = +2

Query: 468 ANNKKIANDVFKKGDQAYLTGDVLVMDELGYLYFRDRTGDTFRWKGENVSTTEVEGTLSR 527
            ++++  +  FK     Y TGD       G+     R  D     G  + T EVE  L  
Sbjct: 20  GDHQRYIDTYFKPCPGVYYTGDGAHRHPGGFYQITGRMDDVVNVTGHRLGTAEVEDVLDD 199

Query: 528 LLHMADVAVYGV--EVPGTEGRAGMAAVASPI--SNCDLES-FAQTLKKELPLYARPIFL 582
            + +A+ AV G   ++ G EG      +      +N ++E+     +K+ +  YA+P F+
Sbjct: 200 HVDVAESAVVGFPHDIKG-EGIFAFVVLKERAMETNKEIEADLKAAIKQRIASYAQPDFI 376

Query: 583 RFLPELHKTGTFKFQKTELRK 603
            F   L KT + K  +  LRK
Sbjct: 377 LFTESLPKTRSGKIMRRVLRK 439
>13327
          Length = 549

 Score = 38.5 bits (88), Expect = 0.009,   Method: Composition-based stats.
 Identities = 37/124 (29%), Positives = 54/124 (43%), Gaps = 6/124 (4%)
 Frame = +3

Query: 487 TGDVLVMDELGYLYFRDRTGDTFRWKGENVSTTEVEGTLSRLLHMADVAVYGVEVPGTEG 546
           +GDV   D  G+LY  DR  +  ++K E V    +E  L     ++D AV G       G
Sbjct: 12  SGDVGYFDSDGFLYIVDRKKELIKFKAEQVPPAMLEDVLLTHPGISDAAVIG-RPDDMAG 188

Query: 547 RAGMAAVASPISNCDL--ESFAQTLKKELPLYARPIFLR----FLPELHKTGTFKFQKTE 600
              MA V    S+ DL  +     + K +P Y +   LR    F  E+ K+ + K  +  
Sbjct: 189 ELPMAFVVKATSHADLTEKEVKDFVAKNVPSYMQ---LRGGVQFKKEIPKSPSGKILRRL 359

Query: 601 LRKE 604
           LR E
Sbjct: 360 LRDE 371
>20450
          Length = 775

 Score = 38.1 bits (87), Expect = 0.012,   Method: Compositional matrix adjust.
 Identities = 22/57 (38%), Positives = 31/57 (54%), Gaps = 1/57 (1%)
 Frame = -3

Query: 483 QAYL-TGDVLVMDELGYLYFRDRTGDTFRWKGENVSTTEVEGTLSRLLHMADVAVYG 538
           Q +L TGDV   D  G+LY  DR  +  ++KGE V+   +E  L     ++D AV G
Sbjct: 470 QGWLKTGDVGQFDSNGFLYIVDRKKELIKYKGEQVAPAMLEDVLLSHPGISDAAVIG 300
>03756
          Length = 992

 Score = 36.6 bits (83), Expect = 0.031,   Method: Compositional matrix adjust.
 Identities = 37/135 (27%), Positives = 56/135 (41%), Gaps = 12/135 (8%)
 Frame = +2

Query: 149 LGVEAALINTNLRRDALRHCLDTSKARALIFGSEMASAICEIHASLEPTLS--LFCSGSW 206
           LG +A +   N  +     C D +KA+ L+   E+A  +        P+L   +F   +W
Sbjct: 464 LGPQACVYIINQTKLCTVVCDDVNKAKRLL---EIADQV--------PSLKRFIFTGKTW 610

Query: 207 EPSTVPVSTEHLDPLL----------EDAPKHLPSHPDKGFTDKLFYIYTSGTTGLPKAA 256
                 ++ E    LL          +D    +P  PD    D     YTSGTTG PK  
Sbjct: 611 PQDIRDLANERKVELLTFKEIESIGTKDTRDPIPPKPD----DLATLCYTSGTTGDPKGV 778

Query: 257 IVVHSRYYRMASLVY 271
           ++ H+ +  M S VY
Sbjct: 779 MLTHANFLIMLSSVY 823
>02626
          Length = 2319

 Score = 32.3 bits (72), Expect = 0.58,   Method: Compositional matrix adjust.
 Identities = 13/31 (41%), Positives = 19/31 (61%)
 Frame = -1

Query: 486  LTGDVLVMDELGYLYFRDRTGDTFRWKGENV 516
             + +++ M +L YLYFR  T D F WK  N+
Sbjct: 1776 FSENIVQMVQLCYLYFRFSTSD*FSWKQFNI 1684
>35736
          Length = 347

 Score = 30.4 bits (67), Expect = 2.3,   Method: Composition-based stats.
 Identities = 13/28 (46%), Positives = 18/28 (64%)
 Frame = -3

Query: 489 DVLVMDELGYLYFRDRTGDTFRWKGENV 516
           +++ M +L YLYFR  T D F WK  N+
Sbjct: 234 NIVQMVQLCYLYFRFSTSD*FSWKQFNI 151
>16584
          Length = 827

 Score = 29.3 bits (64), Expect = 4.7,   Method: Compositional matrix adjust.
 Identities = 13/36 (36%), Positives = 22/36 (61%), Gaps = 2/36 (5%)
 Frame = +3

Query: 169 LDTSKARALIF--GSEMASAICEIHASLEPTLSLFC 202
           L+T +  + I+  GS +A A C++HA + P   +FC
Sbjct: 90  LETKQKLSQIYIQGSNLAGAWCQMHAKVLPCTQIFC 197
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|116063570|ref|NP_034195.2| dynamin [Mus musculus]
         (864 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

29522                                                                 311   8e-85
38072                                                                 100   3e-38
>29522
          Length = 698

 Score =  311 bits (797), Expect = 8e-85,   Method: Compositional matrix adjust.
 Identities = 139/206 (67%), Positives = 175/206 (84%)
 Frame = -3

Query: 344 IEGSGDQIDTYELSGGARINRIFHERFPFELVKMEFDEKELRREISYAIKNIHGIRTGLF 403
           IEG G Q+ T +LSGGA+INRIFHERFPFELVKMEFDE+ELR+EI   I+NIHGIRTGLF
Sbjct: 696 IEGFGAQVSTEDLSGGAKINRIFHERFPFELVKMEFDERELRKEIGITIRNIHGIRTGLF 517

Query: 404 TPDMAFETIVKKQVKKIREPCLKCVDMVISELISTVRQCTKKLQQYPRLREEMERIVTTH 463
           TPDMAFE+IV KQ+++++EP L CVD+VI+EL   VR+  +K+ +YPRLREE ERIV + 
Sbjct: 516 TPDMAFESIVVKQIERLKEPSLHCVDLVITELSQVVRKAGEKMSRYPRLREETERIVNSR 337

Query: 464 IREREGRTKEQVMLLIDIELAYMNTNHEDFIGFANAQQRSNQMNKKKTSGNQVIRKGWLT 523
           IRE+E R KEQ++ LID +LAYMNTNHEDFIGF+NAQQ++   + K+  GNQVIRKGWL+
Sbjct: 336 IREQEQRAKEQILTLIDFQLAYMNTNHEDFIGFSNAQQKAESQSSKRKMGNQVIRKGWLS 157

Query: 524 INNIGIMKGGSKEYWFVLTAENLSWY 549
           ++NI  +KGGSK++WFVLTAE+LSW+
Sbjct: 156 LHNISFIKGGSKDFWFVLTAESLSWF 79
>38072
          Length = 513

 Score =  100 bits (248), Expect(2) = 3e-38,   Method: Compositional matrix adjust.
 Identities = 57/86 (66%), Positives = 64/86 (74%)
 Frame = -3

Query: 607 EEVDSWKASFLRAGVYPERVGDKEKASETEENGSDSFMHSMDPQLERQVETIRNLVDSYM 666
           E+VDSWKASFLRAGVYPER       S  E + S     SMDPQLERQVETIRNLVDSYM
Sbjct: 511 EDVDSWKASFLRAGVYPER-------SSDESSSSKDDYSSMDPQLERQVETIRNLVDSYM 353

Query: 667 AIVNKTVRDLMPKTIMHLMINNTKEF 692
            IVNKT RDL+PKTIMH+++   +E 
Sbjct: 352 KIVNKTQRDLIPKTIMHIIVKKCEEL 275

 Score = 77.8 bits (190), Expect(2) = 3e-38,   Method: Compositional matrix adjust.
 Identities = 43/87 (49%), Positives = 54/87 (62%), Gaps = 2/87 (2%)
 Frame = -1

Query: 688 NTKEFIFSELLANLYSCGDQNTLMEESAEQAQRRDEMLRMYHALKEALSIIGDINXXXXX 747
           N K FI S+LLA+LYS  DQ+ +MEES E+AQRRDE+LRMYHA +EAL+II DI+     
Sbjct: 288 NVKSFIGSDLLAHLYS-NDQSAMMEESQEEAQRRDEILRMYHATREALTIISDISTTTVS 112

Query: 748 XXXXXXXXXXWLQVQ--SVPAGRRSPT 772
                     WL+    S P   R P+
Sbjct: 111 TPTPPPVKDDWLEPSSGSTPYNGRPPS 31
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|167466258|ref|NP_666319.2| cullin 4A [Mus musculus]
         (759 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

02365                                                                 310   2e-84
02265                                                                  89   8e-18
33018                                                                  47   4e-05
>02365
          Length = 1804

 Score =  310 bits (793), Expect = 2e-84,   Method: Compositional matrix adjust.
 Identities = 182/415 (43%), Positives = 247/415 (59%), Gaps = 28/415 (6%)
 Frame = +1

Query: 373 DHVVEVCFQRNERFINLMKESFETFINKRPNKPAELIAKHVDSKLRAGNKEATDEELERI 432
           +H +   F  +++F  ++   FE FIN  P  P E ++  +D KL+ G K  +++E+E +
Sbjct: 532 NHFLHESFNEDKQFKQMISSGFEHFINLNPKSP-EYLSLFIDDKLKKGVKGMSEQEIEVV 708

Query: 433 LDKIMILFRFIHGKDVFEAFYKKDLAKRLLVGKSASVDAEKSMLSKLKHECGAAFTSKLE 492
           LDK M+LFR++  KDVFE +YK+ LA+RLL+ KS S D+EK+M+SKLK ECG  FTSKLE
Sbjct: 709 LDKSMVLFRYLQEKDVFERYYKQHLARRLLLNKSGSDDSEKNMISKLKTECGCQFTSKLE 888

Query: 493 GMFKDMELSKDIMVHFKQHMQNQSAP--GPIDLTVNILTMGYWPTYTPMEVHLPPEMVRL 550
           GMFKDM +S  I   FK  +Q         ++LTV +LT GYWPT +   +++P +    
Sbjct: 889 GMFKDMTVSSGINDEFKASVQQTQVVNLSGVELTVRVLTTGYWPTQSATPINIPVDPRTA 1068

Query: 551 QEVFKTFYLGKHSGRKLQWQTTLGHAVLKADF------------------KEGKKE--FQ 590
            E F+ FYL KHSGR+L  Q  LG A L A F                    G ++   Q
Sbjct: 1069FEAFRRFYLAKHSGRQLTLQPHLGSADLHASFFGQKKDDSADSAAASSSKPAGPRKHILQ 1248

Query: 591 VSLFQTLVLLMFNEGDGFSFEEIKMATGIEDSELRRTLQSLACGK--ARVLIKSPKGKEV 648
           VS +Q  +LL+FN  D ++FEEIK  T + D EL R LQSLA GK   RVL K PK KE+
Sbjct: 1249VSTYQMCILLLFNNRDKWTFEEIKTETDMPDRELIRALQSLAVGKLAQRVLHKEPKTKEI 1428

Query: 649 EDGDKFIFNADFKHKLFRIKINQIQMK--ETVEEQVSTTERVFQDRQYQIDAAIVRIMKM 706
           E    F  N  F  KL R+KI  +     E   E+  T  +V +DR+++I+AAIVRIMK 
Sbjct: 1429EPDHIFTVNDQFTSKLIRVKIQMVASNKGEAEPERKETRNKVDEDRKHEIEAAIVRIMKA 1608

Query: 707 RKTLGHNLLVSELYNQLK--FPVKPGDLKKRIESLIDRDYMERDKDSPNQYHYVA 759
           RK L HN+LV+E+   LK  F   P  +KKRIE LI+R+Y+ R ++    Y YVA
Sbjct: 1609RKKLQHNVLVTEVTEMLKPRFLPSPVVIKKRIEGLIEREYLARSQEDRKIYTYVA 1773

 Score = 97.8 bits (242), Expect = 2e-20,   Method: Compositional matrix adjust.
 Identities = 56/166 (33%), Positives = 92/166 (55%), Gaps = 7/166 (4%)
 Frame = +3

Query: 226 VYKDSFELKFLEETNCLYAAEGQRLMQDREVPEYLNHVSKRLEEEADRVITYLDHSTQKP 285
           VY++ FE  FLE++   Y  E Q+ + +     Y+  V  R+ EEA+R   YLD ST+ P
Sbjct: 69  VYEEDFEKPFLEQSAEFYRLESQKFLAENSASVYIKKVEARINEEAERATHYLDKSTEDP 248

Query: 286 LIACVEKQLLGEHLTAILQ---KGLEHLLDENRVPDLTQMYQLFSRVKGGQHALLQHWSE 342
           ++  +E++L+ +H+  I++    G+ H+L+ N+  DL  MY+LF RV  G   + Q  S+
Sbjct: 249 VVRVLEEELISKHMKTIVEMENSGVVHMLENNKTDDLACMYKLFFRVVYGLRTMCQCISQ 428

Query: 343 YIKTFGTTIVI-NPEKDKDM---VQDLLDFKDKVDHVVEVCFQRNE 384
           +++  G  +VI   E+ K+    VQ LLD  D+        FQR +
Sbjct: 429 FLREQGRALVIEEAEESKNAITYVQSLLDLNDRF*PFPARVFQRGQ 566
>02265
          Length = 1094

 Score = 88.6 bits (218), Expect = 8e-18,   Method: Compositional matrix adjust.
 Identities = 89/353 (25%), Positives = 151/353 (42%), Gaps = 32/353 (9%)
 Frame = +3

Query: 98  VSPTLYKQLRQVCEDHVQAQILPFREDSLDSVLFLKKINTCWQDHCRQMIMIRSIFLFLD 157
           V   LYK+++   ++++   +L   +D LD  + L+     W+D+     ++  I  +L+
Sbjct: 42  VGHELYKRMKDFLKNYL-VNLLKDGQDLLDEQV-LQFYTRQWEDYQFSSKVLDGICAYLN 215

Query: 158 RTYVLQ-----NSMLPSIWDMGLELFRNHIISDRMVQSKTIDGILLLIGRERSGEAVXXX 212
           R +V +        +  I+ + L  +R  +   + +  +  + +L LI +ER+GE +   
Sbjct: 216 RHWVRRECDEGTKGIYYIYSLALITWRECLF--KPLNKQVTNAVLKLIEKERNGETINTR 389

Query: 213 XXXXX--------------XXXXXXXQVYKDSFELKFLEETNCLYAAEGQRLMQDREVPE 258
                                      VYKD FE  FL++T   Y  E    ++   V E
Sbjct: 390 LVSGVINCYVELGLNEEDPSAKGPTLGVYKDHFETPFLDDTERYYTRESTEFLRQNPVTE 569

Query: 259 YLNHVSKRLEEEADRVITYLDHSTQKPLIACVEKQLLGEHLTAILQKGLEHLLDENRVPD 318
           Y+     RL+EE  RV TYL  ST   L    E+ L+ +HL  I     ++LLD ++  D
Sbjct: 570 YMKKAEMRLKEEQKRVQTYLHESTHDSLAKVCERVLIEKHL-EIFHFEFQNLLDTDKNED 746

Query: 319 LTQMYQLFSRVKGGQHALLQHWSEYIKTFGTTIV-----INPEKDKDMVQDLLDFKDKVD 373
           L +MY L SR+  G   L      +I T G   +           K  VQ +LD   K +
Sbjct: 747 LGRMYMLVSRILDGLGELKTLLESHIHTQGLAAIERCGDAALNDPKVYVQTILDVHKKYN 926

Query: 374 HVVEVCFQRNERFINLMKESFETFINKRP--------NKPAELIAKHVDSKLR 418
            +V   F  +  F+  + ++   FIN           +K  EL+A++ D  L+
Sbjct: 927 ALVLTAFVNDAGFVAALDKACGRFINNNSVTKMVNNTSKSPELLARYCDLLLK 1085
>33018
          Length = 814

 Score = 46.6 bits (109), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 25/108 (23%), Positives = 54/108 (50%)
 Frame = -3

Query: 521 IDLTVNILTMGYWPTYTPMEVHLPPEMVRLQEVFKTFYLGKHSGRKLQWQTTLGHAVLKA 580
           +D++  IL+  +WP++   ++ LP ++    + +   Y      R L W+  LG   ++ 
Sbjct: 701 LDISAIILSAQFWPSFREEKITLPAQLQSSLDSYTQQYETLKGNRTLVWKPHLGVMNIEL 522

Query: 581 DFKEGKKEFQVSLFQTLVLLMFNEGDGFSFEEIKMATGIEDSELRRTL 628
           + K+    F VS  Q  +++ F + + ++ E++  A  +  S +RR L
Sbjct: 521 ELKDQTLNFSVSPVQAALIMQFQDQNRWTVEDLGQALEMAPSAVRRKL 378
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|87299637|ref|NP_001034609.1| dynamin 2 [Mus musculus]
         (869 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

29522                                                                 310   2e-84
38072                                                                  96   2e-39
13952                                                                  35   0.16 
08367                                                                  33   0.35 
14762                                                                  32   1.1  
15376                                                                  32   1.3  
>29522
          Length = 698

 Score =  310 bits (793), Expect = 2e-84,   Method: Compositional matrix adjust.
 Identities = 143/210 (68%), Positives = 178/210 (84%)
 Frame = -3

Query: 344 IEGSGDQVDTLELSGGARINRIFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLF 403
           IEG G QV T +LSGGA+INRIFHERFPFELVKMEFDE++LR+EI   I+NIHG+RTGLF
Sbjct: 696 IEGFGAQVSTEDLSGGAKINRIFHERFPFELVKMEFDERELRKEIGITIRNIHGIRTGLF 517

Query: 404 TPDMAFEAIVKKQLVKLKEPSLKCVDLVVSELATVIKKCAEKLSSYPRLREETERIVTTY 463
           TPDMAFE+IV KQ+ +LKEPSL CVDLV++EL+ V++K  EK+S YPRLREETERIV + 
Sbjct: 516 TPDMAFESIVVKQIERLKEPSLHCVDLVITELSQVVRKAGEKMSRYPRLREETERIVNSR 337

Query: 464 IREREGRTKDQILLLIDIEQSYINTNHEDFIGFANAQQRSTQLNKKRAIPNQGEILVIRR 523
           IRE+E R K+QIL LID + +Y+NTNHEDFIGF+NAQQ++   + KR + NQ    VIR+
Sbjct: 336 IREQEQRAKEQILTLIDFQLAYMNTNHEDFIGFSNAQQKAESQSSKRKMGNQ----VIRK 169

Query: 524 GWLTINNISLMKGGSKEYWFVLTAESLSWY 553
           GWL+++NIS +KGGSK++WFVLTAESLSW+
Sbjct: 168 GWLSLHNISFIKGGSKDFWFVLTAESLSWF 79
>38072
          Length = 513

 Score = 96.3 bits (238), Expect(2) = 2e-39,   Method: Compositional matrix adjust.
 Identities = 48/80 (60%), Positives = 60/80 (75%)
 Frame = -3

Query: 611 EDVDSWKASFLRAGVYPEKDQAENEDGAQENTFSMDPQLERQVETIRNLVDSYVAIINKS 670
           EDVDSWKASFLRAGVYPE+   E+     + +    PQLERQVETIRNLVDSY+ I+NK+
Sbjct: 511 EDVDSWKASFLRAGVYPERSSDESSSSKDDYSSMD-PQLERQVETIRNLVDSYMKIVNKT 335

Query: 671 IRDLMPKTIMHLMINNTKAF 690
            RDL+PKTIMH+++   +  
Sbjct: 334 QRDLIPKTIMHIIVKKCEEL 275

 Score = 85.5 bits (210), Expect(2) = 2e-39,   Method: Compositional matrix adjust.
 Identities = 44/86 (51%), Positives = 57/86 (66%)
 Frame = -1

Query: 686 NTKAFIHHELLAYLYSSADQSSLMEESAEQAQRRDDMLRMYHALKEALNIIGDIXXXXXX 745
           N K+FI  +LLA+LYS+ DQS++MEES E+AQRRD++LRMYHA +EAL II DI      
Sbjct: 288 NVKSFIGSDLLAHLYSN-DQSAMMEESQEEAQRRDEILRMYHATREALTIISDISTTTVS 112

Query: 746 XXXXXXXDDTWLQNTSGHSPTPQRRP 771
                   D WL+ +SG +P   R P
Sbjct: 111 TPTPPPVKDDWLEPSSGSTPYNGRPP 34
>13952
          Length = 577

 Score = 34.7 bits (78), Expect = 0.16,   Method: Compositional matrix adjust.
 Identities = 30/123 (24%), Positives = 59/123 (47%), Gaps = 18/123 (14%)
 Frame = -3

Query: 521 IRRGWLTINNISLMKGGS----KEYWFVLTAESLSWYXXXXXXXXXYMLPLDNLKIRDV- 575
           ++ GWL      + +GG     K  WF+L    L ++          ++PL+N+++R++ 
Sbjct: 419 VKEGWL------MKQGGRYKNWKRRWFILNDNCLYYFQYTADKEPKGIIPLENIQVRELS 258

Query: 576 EKGFMSNKHVFAIFNTEQRNVYK------DLRQIE-------LACDSQEDVDSWKASFLR 622
           EK   SN   F +++    +V K      D + +E       ++  S E++D+W +S +R
Sbjct: 257 EKSSRSN--AFELYSVSGSDVIKACKVDSDGKVVEGRHSVYRMSASSAEEMDAWISS-IR 87

Query: 623 AGV 625
            G+
Sbjct: 86  YGI 78
>08367
          Length = 1403

 Score = 33.5 bits (75), Expect = 0.35,   Method: Compositional matrix adjust.
 Identities = 18/59 (30%), Positives = 27/59 (45%)
 Frame = -1

Query: 402 LFTPDMAFEAIVKKQLVKLKEPSLKCVDLVVSELATVIKKCAEKLSSYPRLREETERIV 460
           L TPD           +  K P+L  + +V+  +A +      KLSSYP +R  T R +
Sbjct: 497 LLTPDQILYTPSSLPFLL*KRPNLSSIGIVIPNVAAIFLTSFSKLSSYPHIRSLTVRFM 321
>14762
          Length = 1307

 Score = 32.0 bits (71), Expect = 1.1,   Method: Composition-based stats.
 Identities = 16/36 (44%), Positives = 21/36 (58%)
 Frame = +2

Query: 639  QENTFSMDPQLERQVETIRNLVDSYVAIINKSIRDL 674
            Q+NT S  PQ ERQV   R L  SY   ++++ R L
Sbjct: 1151 QQNTASHAPQQERQVTVQRTLTPSYACKVSRAYRAL 1258
>15376
          Length = 712

 Score = 31.6 bits (70), Expect = 1.3,   Method: Composition-based stats.
 Identities = 22/92 (23%), Positives = 45/92 (48%), Gaps = 14/92 (15%)
 Frame = +1

Query: 542 WFVLTAESLSWYXXXXXXXXXYMLPLDNLKIRDV-EKGFMSNKHVFAIFNTEQRNVYK-- 598
           WF+L    L ++          ++PL+N+++R++ EK   SN   F +++    +V K  
Sbjct: 4   WFILNDNCLYYFQYTADKEPKGIIPLENIQVRELSEKSSRSN--AFELYSVSGSDVIKAC 177

Query: 599 ----DLRQIE-------LACDSQEDVDSWKAS 619
               D + +E       ++  S E++D+W +S
Sbjct: 178 KVDSDGKVVEGRHSVYRMSASSAEEMDAWISS 273
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6680045|ref|NP_032168.1| guanine nucleotide-binding
protein, beta-1 subunit [Mus musculus]
         (340 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

30295                                                                 308   3e-84
17266                                                                 268   2e-72
14555                                                                 100   3e-35
34511                                                                  77   6e-17
17598                                                                  84   1e-16
12806                                                                  77   7e-15
30256                                                                  71   5e-13
00561                                                                  70   2e-12
13335                                                                  69   2e-12
17602                                                                  67   8e-12
27465                                                                  62   3e-10
02147                                                                  62   3e-10
19949                                                                  62   4e-10
02960                                                                  58   6e-09
10162                                                                  57   1e-08
13278                                                                  54   1e-07
01249                                                                  50   9e-07
02090                                                                  50   9e-07
03395                                                                  49   2e-06
12574                                                                  49   4e-06
37180                                                                  46   2e-05
01327                                                                  46   2e-05
03156                                                                  45   3e-05
01805                                                                  44   7e-05
15780                                                                  43   2e-04
26107                                                                  42   3e-04
12960                                                                  42   4e-04
27806                                                                  41   6e-04
21105                                                                  41   8e-04
01462                                                                  40   0.001
34005                                                                  40   0.001
03387                                                                  40   0.002
11493                                                                  39   0.002
03734                                                                  38   0.006
29912                                                                  38   0.006
16199                                                                  37   0.008
19863                                                                  37   0.010
18981                                                                  37   0.011
19498                                                                  36   0.020
31864                                                                  36   0.025
35607                                                                  36   0.026
33180                                                                  35   0.029
26939                                                                  35   0.030
18320                                                                  35   0.041
07665                                                                  35   0.063
14500                                                                  34   0.090
01598                                                                  34   0.10 
15118                                                                  33   0.15 
21921                                                                  32   0.27 
04358                                                                  32   0.34 
15337                                                                  32   0.36 
20662                                                                  32   0.44 
10264                                                                  31   0.69 
31054                                                                  31   0.77 
15972                                                                  30   1.3  
27270                                                                  30   1.5  
27525                                                                  30   1.6  
22113                                                                  30   1.9  
31384                                                                  29   2.8  
11915                                                                  29   2.8  
12140                                                                  29   3.3  
04524                                                                  28   5.3  
07781                                                                  28   5.6  
38177                                                                  27   8.0  
27681                                                                  27   8.2  
>30295
          Length = 593

 Score =  308 bits (788), Expect = 3e-84,   Method: Compositional matrix adjust.
 Identities = 147/169 (86%), Positives = 153/169 (90%)
 Frame = +2

Query: 2   SELDQLRQEAEQLKNQIRDARKACADATLSQITNNIDPVGRIQMRTRRTLRGHLAKIYAM 61
           SELD LRQE EQLKNQIR+ARKA  D TL+Q T + D VGRIQMRTRRTLR HLAKIYAM
Sbjct: 86  SELDALRQETEQLKNQIREARKAAGDTTLAQATASYDSVGRIQMRTRRTLRXHLAKIYAM 265

Query: 62  HWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNIC 121
           HW TDSR LVSASQDGKLI+WD YTTNKVHAIPLRSSWVMTCAYAPSG YVACGGLDNIC
Sbjct: 266 HWATDSRNLVSASQDGKLIVWDGYTTNKVHAIPLRSSWVMTCAYAPSGGYVACGGLDNIC 445

Query: 122 SIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTTCALWD 170
           SIY+LKTREGNVRVSREL GHTGYLSCCRF+DDNQIVTSSGD TCALWD
Sbjct: 446 SIYSLKTREGNVRVSRELPGHTGYLSCCRFIDDNQIVTSSGDMTCALWD 592
>17266
          Length = 480

 Score =  268 bits (685), Expect = 2e-72,   Method: Compositional matrix adjust.
 Identities = 126/147 (85%), Positives = 137/147 (93%)
 Frame = -1

Query: 190 LSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDAT 249
           LSLAPD R FVSGACDASAKLWDVR+GMC+QTF+GHESDINAI +FPNG+AFATGSDDAT
Sbjct: 441 LSLAPDMRTFVSGACDASAKLWDVRDGMCKQTFSGHESDINAITYFPNGHAFATGSDDAT 262

Query: 250 CRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLA 309
           CRLFD+RADQE+  YSHDNIICGITSV+FSKSGRLLL GYDDFNCN+WD LK +R GVLA
Sbjct: 261 CRLFDIRADQEIGMYSHDNIICGITSVAFSKSGRLLLGGYDDFNCNIWDVLKQERTGVLA 82

Query: 310 GHDNRVSCLGVTDDGMAVATGSWDSFL 336
           GHDNRVSCLGVT+DG AVATGSWDSFL
Sbjct: 81  GHDNRVSCLGVTEDGSAVATGSWDSFL 1

 Score = 37.7 bits (86), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 33/146 (22%), Positives = 63/146 (43%), Gaps = 3/146 (2%)
 Frame = -1

Query: 106 APSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQ-IVTSSGDT 164
           AP       G  D    ++++  R+G  +  +  +GH   ++   +  +     T S D 
Sbjct: 432 APDMRTFVSGACDASAKLWDV--RDGMCK--QTFSGHESDINAITYFPNGHAFATGSDDA 265

Query: 165 TCALWDI--EXXXXXXXXXXXXXDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTF 222
           TC L+DI  +              + S++ +   RL + G  D +  +WDV +       
Sbjct: 264 TCRLFDIRADQEIGMYSHDNIICGITSVAFSKSGRLLLGGYDDFNCNIWDVLKQERTGVL 85

Query: 223 TGHESDINAICFFPNGNAFATGSDDA 248
            GH++ ++ +    +G+A ATGS D+
Sbjct: 84  AGHDNRVSCLGVTEDGSAVATGSWDS 7

 Score = 27.3 bits (59), Expect = 9.2,   Method: Compositional matrix adjust.
 Identities = 15/65 (23%), Positives = 33/65 (50%)
 Frame = -1

Query: 276 VSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSF 335
           +S +   R  ++G  D +  +WD          +GH++ ++ +    +G A ATGS D+ 
Sbjct: 441 LSLAPDMRTFVSGACDASAKLWDVRDGMCKQTFSGHESDINAITYFPNGHAFATGSDDAT 262

Query: 336 LKIWN 340
            ++++
Sbjct: 261 CRLFD 247
>14555
          Length = 627

 Score = 99.8 bits (247), Expect(2) = 3e-35,   Method: Compositional matrix adjust.
 Identities = 46/73 (63%), Positives = 57/73 (78%)
 Frame = -2

Query: 218 CRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVS 277
           C Q F GHE+DIN + F+P+G+AFATGSDDATCRLFDLRAD+E+  Y  ++II G  +V 
Sbjct: 623 CVQMFEGHEADINCVRFYPSGDAFATGSDDATCRLFDLRADREVNCYRKESIIFGCNAVD 444

Query: 278 FSKSGRLLLAGYD 290
           FS SGRLL  GY+
Sbjct: 443 FSVSGRLLFGGYE 405

 Score = 66.6 bits (161), Expect(2) = 3e-35,   Method: Compositional matrix adjust.
 Identities = 29/50 (58%), Positives = 38/50 (76%)
 Frame = -3

Query: 290 DDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIW 339
           +D+  NVWDALK  R+ +L GHDNRVSCL ++ DG ++ TGSWD  L+IW
Sbjct: 406 NDYTVNVWDALKGMRSTILYGHDNRVSCLRISPDGTSLCTGSWDYTLRIW 257

 Score = 35.8 bits (81), Expect = 0.025,   Method: Compositional matrix adjust.
 Identities = 15/49 (30%), Positives = 27/49 (55%)
 Frame = -3

Query: 205 DASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLF 253
           D +  +WD  +GM      GH++ ++ +   P+G +  TGS D T R++
Sbjct: 403 DYTVNVWDALKGMRSTILYGHDNRVSCLRISPDGTSLCTGSWDYTLRIW 257
>34511
          Length = 1037

 Score = 77.4 bits (189), Expect(2) = 6e-17,   Method: Compositional matrix adjust.
 Identities = 32/40 (80%), Positives = 40/40 (100%)
 Frame = +3

Query: 301 KADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
           KA+R+G+LAGHDNRVSCLGVT++GM+VATGSWDSFL++WN
Sbjct: 39  KAERSGILAGHDNRVSCLGVTENGMSVATGSWDSFLRVWN 158

 Score = 27.3 bits (59), Expect(2) = 6e-17,   Method: Compositional matrix adjust.
 Identities = 10/18 (55%), Positives = 13/18 (72%)
 Frame = +2

Query: 289 YDDFNCNVWDALKADRAG 306
           YDDFNCNVW  +++   G
Sbjct: 2   YDDFNCNVWYTMESRALG 55
>17598
          Length = 875

 Score = 83.6 bits (205), Expect = 1e-16,   Method: Compositional matrix adjust.
 Identities = 62/256 (24%), Positives = 109/256 (42%), Gaps = 14/256 (5%)
 Frame = +1

Query: 48  RRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAP 107
           RRTL+GH   +  +    DSR ++S+S D  L +WD    N        +   +  A++P
Sbjct: 100 RRTLQGHSHFVSDVSLSADSRYVLSSSWDATLRLWDIKKGNTTRRFISHTRDALAVAFSP 279

Query: 108 SGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQ---IVTSSGDT 164
               +A GG D    I+N     G  + + +   H  +++C +F  D +   +V++S D 
Sbjct: 280 DNRQIASGGRDKALKIWNT---VGECKFTVDANSHQDWVTCVKFHQDAKSPLVVSASMDK 450

Query: 165 TCALWDIEXXXXXXXXXXXXXDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTG 224
           T  +WD +              + ++ LA  T    SG+ D     W+++ G    TF G
Sbjct: 451 TIKVWDNQTMTLKHTFVGHKTQINAIDLALKTYYLASGSKDGIVMTWNIQNG----TFLG 618

Query: 225 H---ESDINAICFFPNGNAFATGSDDA--------TCRLFDLRADQELMTYSHDNIICGI 273
               + ++NA+ F PN      G+ +           ++ D+RA      +         
Sbjct: 619 KIDCDCEVNAVKFSPNKYWLFVGTSEGIQIWDLPNQKKIKDIRASPIDAQHKSQKKSIAC 798

Query: 274 TSVSFSKSGRLLLAGY 289
           TS+++  SG  L AG+
Sbjct: 799 TSLAWDASGHTLFAGF 846

 Score = 63.5 bits (153), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 39/158 (24%), Positives = 74/158 (46%), Gaps = 4/158 (2%)
 Frame = +1

Query: 187 VMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSD 246
           V  +SL+ D+R  +S + DA+ +LWD+++G   + F  H  D  A+ F P+    A+G  
Sbjct: 130 VSDVSLSADSRYVLSSSWDATLRLWDIKKGNTTRRFISHTRDALAVAFSPDNRQIASGGR 309

Query: 247 DATCRLFDLRADQELMT--YSHDNIICGITSVSFSKSGR--LLLAGYDDFNCNVWDALKA 302
           D   ++++   + +      SH +    +T V F +  +  L+++   D    VWD    
Sbjct: 310 DKALKIWNTVGECKFTVDANSHQD---WVTCVKFHQDAKSPLVVSASMDKTIKVWDNQTM 480

Query: 303 DRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
                  GH  +++ + +      +A+GS D  +  WN
Sbjct: 481 TLKHTFVGHKTQINAIDLALKTYYLASGSKDGIVMTWN 594

 Score = 28.5 bits (62), Expect = 4.1,   Method: Compositional matrix adjust.
 Identities = 12/33 (36%), Positives = 21/33 (63%)
 Frame = +1

Query: 308 LAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
           L GH + VS + ++ D   V + SWD+ L++W+
Sbjct: 109 LQGHSHFVSDVSLSADSRYVLSSSWDATLRLWD 207
>12806
          Length = 961

 Score = 77.4 bits (189), Expect = 7e-15,   Method: Compositional matrix adjust.
 Identities = 56/193 (29%), Positives = 88/193 (45%), Gaps = 6/193 (3%)
 Frame = +3

Query: 48  RRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAP 107
           R+TL GH   I  +    DSR  +S+S D  L +WD    +        +  V+T A++P
Sbjct: 144 RKTLTGHSHFISDLALSADSRFALSSSWDATLRLWDIKKGSTTSRFINHTRDVLTVAFSP 323

Query: 108 SGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQ---IVTSSGDT 164
               +A GG D    I+N+    G  + + +   HT +++C RF  D +   +V++S D 
Sbjct: 324 DNRQIASGGRDKNLKIWNIM---GECKYTVDANAHTDWVTCVRFHQDTKNPIVVSASNDK 494

Query: 165 TCALWDIEXXXXXXXXXXXXXDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTG 224
           T  +WD                + +L ++  T   VSG+ D  A  W+V EG    +F G
Sbjct: 495 TIKVWDNHTMTLKNTFVGHKAQITALDMS--TNYLVSGSKDGIAMTWNVAEG----SFVG 656

Query: 225 H---ESDINAICF 234
               +  INAI F
Sbjct: 657 KIDCDDQINAIKF 695

 Score = 52.8 bits (125), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 46/209 (22%), Positives = 90/209 (43%), Gaps = 11/209 (5%)
 Frame = +3

Query: 111 YVACGGLDNICSIYNL-KTREGNVRVS-----RELAGHTGYLSCCRFLDDNQI-VTSSGD 163
           ++  GG DN   +++L   ++G+   +     + L GH+ ++S      D++  ++SS D
Sbjct: 51  FLISGGRDNNIIVWDL*PKKDGDEDQTWGVPRKTLTGHSHFISDLALSADSRFALSSSWD 230

Query: 164 TTCALWDIEXXXXXXXXXXXXXDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTF- 222
            T  LWDI+             DV++++ +PD R   SG  D + K+W++  G C+ T  
Sbjct: 231 ATLRLWDIKKGSTTSRFINHTRDVLTVAFSPDNRQIASGGRDKNLKIWNIM-GECKYTVD 407

Query: 223 -TGHESDINAICFFPN--GNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFS 279
              H   +  + F  +       + S+D T +++    D   MT  +  +       +  
Sbjct: 408 ANAHTDWVTCVRFHQDTKNPIVVSASNDKTIKVW----DNHTMTLKNTFVGHKAQITALD 575

Query: 280 KSGRLLLAGYDDFNCNVWDALKADRAGVL 308
            S   L++G  D     W+  +    G +
Sbjct: 576 MSTNYLVSGSKDGIAMTWNVAEGSFVGKI 662

 Score = 30.0 bits (66), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 20/68 (29%), Positives = 32/68 (47%), Gaps = 11/68 (16%)
 Frame = +3

Query: 284 LLLAGYDDFNCNVWDALKADRAG-----------VLAGHDNRVSCLGVTDDGMAVATGSW 332
            L++G  D N  VWD L   + G            L GH + +S L ++ D     + SW
Sbjct: 51  FLISGGRDNNIIVWD-L*PKKDGDEDQTWGVPRKTLTGHSHFISDLALSADSRFALSSSW 227

Query: 333 DSFLKIWN 340
           D+ L++W+
Sbjct: 228 DATLRLWD 251
>30256
          Length = 961

 Score = 71.2 bits (173), Expect = 5e-13,   Method: Compositional matrix adjust.
 Identities = 45/144 (31%), Positives = 72/144 (50%), Gaps = 2/144 (1%)
 Frame = +3

Query: 199 FVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRAD 258
            +SG+ D S K+W+   G+C  T  GH S +   C   +G    +GS DAT R++D+ + 
Sbjct: 81  VISGSTDRSLKVWNADTGVCTHTLYGHSSTVR--CLSLSGKKVVSGSRDATLRVWDIESG 254

Query: 259 QELMTYSHDNIICGITSV--SFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVS 316
             L      N++ G  +        G+ +++G  D+   VWD   A     L GH NRV 
Sbjct: 255 HCL------NVLLGHMAAVRCVQYDGKRVVSGAXDYTVRVWDPDTASCLHTLQGHTNRVY 416

Query: 317 CLGVTDDGMAVATGSWDSFLKIWN 340
            L    DG+ V +GS D+ +++W+
Sbjct: 417 SLQF--DGVYVVSGSLDTSIRVWD 482

 Score = 65.1 bits (157), Expect = 4e-11,   Method: Compositional matrix adjust.
 Identities = 65/263 (24%), Positives = 109/263 (41%), Gaps = 18/263 (6%)
 Frame = +3

Query: 49  RTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPS 108
            TL GH + +  +      + +VS S+D  L +WD  + + ++ +    + V    Y   
Sbjct: 144 HTLYGHSSTVRCL--SLSGKKVVSGSRDATLRVWDIESGHCLNVLLGHMAAVRCVQY--D 311

Query: 109 GNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTTCAL 168
           G  V  G  D    +++  T          L GHT  +   +F D   +V+ S DT+  +
Sbjct: 312 GKRVVSGAXDYTVRVWDPDTAS----CLHTLQGHTNRVYSLQF-DGVYVVSGSLDTSIRV 476

Query: 169 WDIEXXXXXXXXXXXXXDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESD 228
           WD+                  L L  +  L VSG  D++ K+WDV  G C QT  G    
Sbjct: 477 WDVRCGKLVHTLMGHQSLTSGLELKDN--LLVSGNADSTVKVWDVHTGKCLQTLLGPNKH 650

Query: 229 INAI-CFFPNGNAFATGSDDATCRLFDLRAD---QELMTY--------------SHDNII 270
            +A+ C   N     T SDD T +L+DL      + L+T               ++  ++
Sbjct: 651 RSAVTCLQFNKKFVVTCSDDGTVKLWDLNTGDFIRNLITLPSGGSGGVVWRLRCNNTKMV 830

Query: 271 CGITSVSFSKSGRLLLAGYDDFN 293
           C + S + ++  +LL+  +D  N
Sbjct: 831 CAVGSRNGTEETKLLVLDFDQVN 899

 Score = 64.3 bits (155), Expect = 6e-11,   Method: Compositional matrix adjust.
 Identities = 54/208 (25%), Positives = 93/208 (44%), Gaps = 1/208 (0%)
 Frame = +3

Query: 134 RVSRELAGHTGYLSCCRFLDDNQIVTSSGDTTCALWDIEXXXXXXXXXXXXXDVMSLSLA 193
           R  + L GHTG +   + +  N +++ S D +  +W+ +              V  LSL+
Sbjct: 15  RCIKNLIGHTGGVWSSQ-MTGNTVISGSTDRSLKVWNADTGVCTHTLYGHSSTVRCLSLS 191

Query: 194 PDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLF 253
              +  VSG+ DA+ ++WD+  G C     GH + +   C   +G    +G+ D T R++
Sbjct: 192 G--KKVVSGSRDATLRVWDIESGHCLNVLLGHMAAVR--CVQYDGKRVVSGAXDYTVRVW 359

Query: 254 DLRADQELMTYS-HDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHD 312
           D      L T   H N +      S    G  +++G  D +  VWD         L GH 
Sbjct: 360 DPDTASCLHTLQGHTNRV-----YSLQFDGVYVVSGSLDTSIRVWDVRCGKLVHTLMGHQ 524

Query: 313 NRVSCLGVTDDGMAVATGSWDSFLKIWN 340
           +  S L + D+   + +G+ DS +K+W+
Sbjct: 525 SLTSGLELKDN--LLVSGNADSTVKVWD 602
>00561
          Length = 1003

 Score = 69.7 bits (169), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 60/246 (24%), Positives = 103/246 (41%), Gaps = 13/246 (5%)
 Frame = -3

Query: 66  DSRLLVSASQDGKLIIWD---------SYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGG 116
           D   ++SAS+D  LI+W           Y   +++     S ++     +  GNY   G 
Sbjct: 977 DPDTIISASRDKTLIVWKLTRDEDTNYGYPQKRLYG---HSHFISDVVLSSDGNYALSGS 807

Query: 117 LDNICSIYNLKTREGNVRVSRELAGHTG-YLSCCRFLDDNQIVTSSGDTTCALWDIEXXX 175
            D    +++L       + +R   GHT   LS     D+ QIV+ S D T  LW+     
Sbjct: 806 WDQTLRLWDLAAG----KTTRRFEGHTKDVLSVAFSADNRQIVSGSRDKTIKLWNTLAEC 639

Query: 176 XXXXXXXXXXDVMS-LSLAPD--TRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAI 232
                     D +S +  +P+    + VS   D + K+W++     +    GH   +N +
Sbjct: 638 KFTIQEDGHTDWVSCVRFSPNHSNPIIVSCGWDRTVKVWNLANCKLKNNHHGHNGYLNTV 459

Query: 233 CFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDF 292
              P+G+   +G  D+   L+DL   + L T  H++I   I ++ FS +   L   Y   
Sbjct: 458 TVSPDGSLCTSGGKDSKALLWDLNDGKNLYTLEHNDI---INALCFSPNRYWLCVAYGP- 291

Query: 293 NCNVWD 298
           +  +WD
Sbjct: 290 SIKIWD 273

 Score = 56.2 bits (134), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 45/196 (22%), Positives = 84/196 (42%), Gaps = 8/196 (4%)
 Frame = -3

Query: 153 DDNQIVTSSGDTTCALW------DIEXXXXXXXXXXXXXDVMSLSLAPDTRLFVSGACDA 206
           D + I+++S D T  +W      D                +  + L+ D    +SG+ D 
Sbjct: 977 DPDTIISASRDKTLIVWKLTRDEDTNYGYPQKRLYGHSHFISDVVLSSDGNYALSGSWDQ 798

Query: 207 SAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSH 266
           + +LWD+  G   + F GH  D+ ++ F  +     +GS D T +L++  A+ +  T   
Sbjct: 797 TLRLWDLAAGKTTRRFEGHTKDVLSVAFSADNRQIVSGSRDKTIKLWNTLAECKF-TIQE 621

Query: 267 DNIICGITSVSFSK--SGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDG 324
           D     ++ V FS   S  ++++   D    VW+           GH+  ++ + V+ DG
Sbjct: 620 DGHTDWVSCVRFSPNHSNPIIVSCGWDRTVKVWNLANCKLKNNHHGHNGYLNTVTVSPDG 441

Query: 325 MAVATGSWDSFLKIWN 340
               +G  DS   +W+
Sbjct: 440 SLCTSGGKDSKALLWD 393

 Score = 51.2 bits (121), Expect = 6e-07,   Method: Compositional matrix adjust.
 Identities = 42/172 (24%), Positives = 74/172 (43%), Gaps = 4/172 (2%)
 Frame = -3

Query: 46  RTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIP-LRSSWVMTCA 104
           +T R   GH   + ++ +  D+R +VS S+D  + +W++    K        + WV    
Sbjct: 767 KTTRRFEGHTKDVLSVAFSADNRQIVSGSRDKTIKLWNTLAECKFTIQEDGHTDWVSCVR 588

Query: 105 YAP--SGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSG 162
           ++P  S   +   G D    ++NL     N ++     GH GYL+      D  + TS G
Sbjct: 587 FSPNHSNPIIVSCGWDRTVKVWNL----ANCKLKNNHHGHNGYLNTVTVSPDGSLCTSGG 420

Query: 163 -DTTCALWDIEXXXXXXXXXXXXXDVMSLSLAPDTRLFVSGACDASAKLWDV 213
            D+   LWD+               + +L  +P+ R ++  A   S K+WD+
Sbjct: 419 KDSKALLWDLNDGKNLYTLEHNDI-INALCFSPN-RYWLCVAYGPSIKIWDL 270
>13335
          Length = 863

 Score = 69.3 bits (168), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 61/240 (25%), Positives = 103/240 (42%), Gaps = 22/240 (9%)
 Frame = +1

Query: 123 IYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTTCALWDIEXXXXXXXXXX 182
           ++++KT  G+++   + A  +    C      + +V+ S D T  +W++           
Sbjct: 10  VWDVKT--GSIKGEYQHASKSSIRVCKFSPSSSHLVSGSDDDTICMWEVATQKLVRSYVG 183

Query: 183 XXXDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQ-TFTGHESDINAIC--FFPN-G 238
               VM+L+ +P+    VSG+ +    +WD   G CR  T      D+   C  F P  G
Sbjct: 184 HEDSVMALAYSPNGHYLVSGSPNGDLYVWDASFGHCRHLTLRVDAHDLGVTCCEFSPTFG 363

Query: 239 NA-----------FATGSDDATCRL--FDLRADQELMTYSHDNIICG----ITSVSFSKS 281
            A            ATG  D   +L  F  +     +T    +I+ G    + + +FS S
Sbjct: 364 TACAENSSTCNLLLATGGKDNLIKLWTFSAQVGSPEVTLQCRDILSGHSDLVMACAFSPS 543

Query: 282 GRLLLAGYDDFNCNVWDALK-ADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
             LL +G  D +  +WD++K      + A H   V+C   + DG  +A+GS D  +KIW 
Sbjct: 544 SALLASGSFDKSVRLWDSVKGVALFSIEACHSRFVTCCAFSIDGTLLASGSMDRIIKIWK 723

 Score = 55.1 bits (131), Expect = 4e-08,   Method: Compositional matrix adjust.
 Identities = 52/230 (22%), Positives = 87/230 (37%), Gaps = 23/230 (10%)
 Frame = +1

Query: 56  AKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACG 115
           + I    +   S  LVS S D  + +W+  T   V +       VM  AY+P+G+Y+  G
Sbjct: 64  SSIRVCKFSPSSSHLVSGSDDDTICMWEVATQKLVRSYVGHEDSVMALAYSPNGHYLVSG 243

Query: 116 GLDNICSIYNLKTREGNVR-VSRELAGHTGYLSCCRFLDDNQIVTSSGDTTC-------- 166
             +    +Y      G+ R ++  +  H   ++CC F        +   +TC        
Sbjct: 244 SPNG--DLYVWDASFGHCRHLTLRVDAHDLGVTCCEFSPTFGTACAENSSTCNLLLATGG 417

Query: 167 -----ALWDIEXXXXXXXXXXXXXD--------VMSLSLAPDTRLFVSGACDASAKLWDV 213
                 LW                D        VM+ + +P + L  SG+ D S +LWD 
Sbjct: 418 KDNLIKLWTFSAQVGSPEVTLQCRDILSGHSDLVMACAFSPSSALLASGSFDKSVRLWDS 597

Query: 214 REGMCRQTFTGHESDINAICFFP-NGNAFATGSDDATCRLFDLRADQELM 262
            +G+   +     S     C F  +G   A+GS D   +++ L     +M
Sbjct: 598 VKGVALFSIEACHSRFVTCCAFSIDGTLLASGSMDRIIKIWKLTDTSSIM 747

 Score = 48.5 bits (114), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 45/191 (23%), Positives = 81/191 (42%), Gaps = 24/191 (12%)
 Frame = +1

Query: 49  RTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDS------YTTNKVHAIPLRSSWVMT 102
           R+  GH   + A+ +  +   LVS S +G L +WD+      + T +V A  L    V  
Sbjct: 169 RSYVGHEDSVMALAYSPNGHYLVSGSPNGDLYVWDASFGHCRHLTLRVDAHDLG---VTC 339

Query: 103 CAYAPSGN------------YVACGGLDNICSIYNLKTREGNVRVSRE----LAGHTGYL 146
           C ++P+               +A GG DN+  ++    + G+  V+ +    L+GH+  +
Sbjct: 340 CEFSPTFGTACAENSSTCNLLLATGGKDNLIKLWTFSAQVGSPEVTLQCRDILSGHSDLV 519

Query: 147 SCCRFLDDNQIVTS-SGDTTCALWD-IEXXXXXXXXXXXXXDVMSLSLAPDTRLFVSGAC 204
             C F   + ++ S S D +  LWD ++              V   + + D  L  SG+ 
Sbjct: 520 MACAFSPSSALLASGSFDKSVRLWDSVKGVALFSIEACHSRFVTCCAFSIDGTLLASGSM 699

Query: 205 DASAKLWDVRE 215
           D   K+W + +
Sbjct: 700 DRIIKIWKLTD 732

 Score = 41.2 bits (95), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 26/86 (30%), Positives = 41/86 (47%), Gaps = 1/86 (1%)
 Frame = +1

Query: 42  RIQMRTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAI-PLRSSWV 100
            + ++ R  L GH   + A  +   S LL S S D  + +WDS     + +I    S +V
Sbjct: 469 EVTLQCRDILSGHSDLVMACAFSPSSALLASGSFDKSVRLWDSVKGVALFSIEACHSRFV 648

Query: 101 MTCAYAPSGNYVACGGLDNICSIYNL 126
             CA++  G  +A G +D I  I+ L
Sbjct: 649 TCCAFSIDGTLLASGSMDRIIKIWKL 726
>17602
          Length = 481

 Score = 67.4 bits (163), Expect = 8e-12,   Method: Compositional matrix adjust.
 Identities = 40/135 (29%), Positives = 64/135 (47%), Gaps = 3/135 (2%)
 Frame = +3

Query: 209 KLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDN 268
           ++WDV+ G C +T   H   + A+ F  +G+   + S D  CR++D  + Q L T   D+
Sbjct: 3   RIWDVKTGKCLKTLPAHSDPVTAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLXTLIDDD 182

Query: 269 IICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGV---TDDGM 325
               ++ V FS +G+ +LA   D    +WD  K        GH N   C+        G 
Sbjct: 183 NP-PVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYVGHRNEKYCIFANFSVTGGK 359

Query: 326 AVATGSWDSFLKIWN 340
            + +GS D+ + IWN
Sbjct: 360 WIVSGSEDNMVYIWN 404

 Score = 50.1 bits (118), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 37/139 (26%), Positives = 63/139 (45%), Gaps = 9/139 (6%)
 Frame = +3

Query: 137 RELAGHTGYLSCCRF-LDDNQIVTSSGDTTCALWDIEXXXXXXXXXXXXXDVMS-LSLAP 194
           + L  H+  ++   F  D + IV+SS D  C +WD                 +S +  +P
Sbjct: 36  KTLPAHSDPVTAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLXTLIDDDNPPVSFVKFSP 215

Query: 195 DTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPN-----GNAFATGSDDAT 249
           + +  ++   D + KLWD  +G C +T+ GH ++    C F N     G    +GS+D  
Sbjct: 216 NGKYILAATLDNTLKLWDYSKGKCLKTYVGHRNE--KYCIFANFSVTGGKWIVSGSEDNM 389

Query: 250 CRLFDL--RADQELMTYSH 266
             +++L  + D    T SH
Sbjct: 390 VYIWNLLDQGDSTEATGSH 446

 Score = 45.8 bits (107), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 32/135 (23%), Positives = 57/135 (42%), Gaps = 2/135 (1%)
 Frame = +3

Query: 168 LWDIEXXXXXXXXXXXXXDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHES 227
           +WD++              V ++    D  L VS + D   ++WD   G C  T    ++
Sbjct: 6   IWDVKTGKCLKTLPAHSDPVTAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLXTLIDDDN 185

Query: 228 -DINAICFFPNGNAFATGSDDATCRLFDLRADQELMTY-SHDNIICGITSVSFSKSGRLL 285
             ++ + F PNG      + D T +L+D    + L TY  H N    I +      G+ +
Sbjct: 186 PPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYVGHRNEKYCIFANFSVTGGKWI 365

Query: 286 LAGYDDFNCNVWDAL 300
           ++G +D    +W+ L
Sbjct: 366 VSGSEDNMVYIWNLL 410

 Score = 38.9 bits (89), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 31/128 (24%), Positives = 54/128 (42%), Gaps = 5/128 (3%)
 Frame = +3

Query: 49  RTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHA-IPLRSSWVMTCAYAP 107
           +TL  H   + A+H+  D  L+VS+S DG   IWD+ +   +   I   +  V    ++P
Sbjct: 36  KTLPAHSDPVTAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLXTLIDDDNPPVSFVKFSP 215

Query: 108 SGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCC----RFLDDNQIVTSSGD 163
           +G Y+    LDN   +++        +  +   GH     C            IV+ S D
Sbjct: 216 NGKYILAATLDNTLKLWDYSKG----KCLKTYVGHRNEKYCIFANFSVTGGKWIVSGSED 383

Query: 164 TTCALWDI 171
               +W++
Sbjct: 384 NMVYIWNL 407
>27465
          Length = 658

 Score = 62.4 bits (150), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 33/106 (31%), Positives = 50/106 (47%), Gaps = 1/106 (0%)
 Frame = -1

Query: 155 NQIVTSSGDTTCALWDIEXXXXXXXXXXXXXDVMSLSLA-PDTRLFVSGACDASAKLWDV 213
           +  +T S D TC +WD                V +++   P     ++G+ D + KLW  
Sbjct: 322 SSFITGSYDRTCKIWDTASAEELHTLEGHRNVVYAIAFNNPFGDKVITGSFDKTCKLWST 143

Query: 214 REGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQ 259
            +G C  T  GH ++I  + F P+    ATGS D TCRL+D+   Q
Sbjct: 142 ADGKCYHTLRGHTAEIVCVSFNPSSTLIATGSMDTTCRLWDVEKAQ 5

 Score = 57.4 bits (137), Expect = 9e-09,   Method: Compositional matrix adjust.
 Identities = 38/110 (34%), Positives = 56/110 (50%), Gaps = 4/110 (3%)
 Frame = -1

Query: 199 FVSGACDASAKLWDVREGMCRQTFTGHESDINAICFF-PNGNAFATGSDDATCRLF---D 254
           F++G+ D + K+WD        T  GH + + AI F  P G+   TGS D TC+L+   D
Sbjct: 316 FITGSYDRTCKIWDTASAEELHTLEGHRNVVYAIAFNNPFGDKVITGSFDKTCKLWSTAD 137

Query: 255 LRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADR 304
            +    L  ++ + I+C    VSF+ S  L+  G  D  C +WD  KA R
Sbjct: 136 GKCYHTLRGHTAE-IVC----VSFNPSSTLIATGSMDTTCRLWDVEKAQR 2

 Score = 56.6 bits (135), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 35/126 (27%), Positives = 60/126 (47%), Gaps = 2/126 (1%)
 Frame = -1

Query: 49  RTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAY-AP 107
           + LR H+  +  + +       ++ S D    IWD+ +  ++H +    + V   A+  P
Sbjct: 379 KVLRAHILPLTNVAFNKSGSSFITGSYDRTCKIWDTASAEELHTLEGHRNVVYAIAFNNP 200

Query: 108 SGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIV-TSSGDTTC 166
            G+ V  G  D  C +++  T +G  +    L GHT  + C  F   + ++ T S DTTC
Sbjct: 199 FGDKVITGSFDKTCKLWS--TADG--KCYHTLRGHTAEIVCVSFNPSSTLIATGSMDTTC 32

Query: 167 ALWDIE 172
            LWD+E
Sbjct: 31  RLWDVE 14

 Score = 56.2 bits (134), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 33/123 (26%), Positives = 58/123 (47%), Gaps = 2/123 (1%)
 Frame = -1

Query: 220 QTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYS-HDNIICGITSVSF 278
           +    H   +  + F  +G++F TGS D TC+++D  + +EL T   H N++  I   +F
Sbjct: 379 KVLRAHILPLTNVAFNKSGSSFITGSYDRTCKIWDTASAEELHTLEGHRNVVYAI---AF 209

Query: 279 SKS-GRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLK 337
           +   G  ++ G  D  C +W          L GH   + C+        +ATGS D+  +
Sbjct: 208 NNPFGDKVITGSFDKTCKLWSTADGKCYHTLRGHTAEIVCVSFNPSSTLIATGSMDTTCR 29

Query: 338 IWN 340
           +W+
Sbjct: 28  LWD 20
>02147
          Length = 1547

 Score = 62.0 bits (149), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 53/221 (23%), Positives = 82/221 (37%), Gaps = 38/221 (17%)
 Frame = +2

Query: 158 VTSSGDTTCALWDIEXXXXXXXXXXXXXDVMSLSLAPDTRLFVSGACDASAKLWD-VREG 216
            T + D +  +WD E              V S+  + D    ++G+ +   K++D V   
Sbjct: 221 ATGAADFSAKIWDAEKGEELQTFSHKHI-VKSVDFSHDGTALLTGSNEKLLKVFDLVNTD 397

Query: 217 MCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHD--------- 267
              ++F GH S+I    F  +G    + SDD T RL+ L   QE+   + D         
Sbjct: 398 AEPKSFAGHTSNIKGALFLSDGKRIISASDDKTVRLWSLETCQEVQQLTFDTPPTSLTLS 577

Query: 268 ---NII-------------------------CGITSVSFSKSGRLLLAGYDDFNCNVWDA 299
              N I                           I+S S  +S R  +AG +DF    +D 
Sbjct: 578 PDKNTIIVTHSQNIAFYQADTLREMKKFEAEAPISSASLHQSERFFVAGGEDFKMYKFDY 757

Query: 300 LKADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
                     GH   V C+  + DG   A+GS D  L++W 
Sbjct: 758 ETGKEIESFKGHFGPVHCVRFSPDGELYASGSEDGTLRLWQ 880

 Score = 60.1 bits (144), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 50/244 (20%), Positives = 90/244 (36%), Gaps = 41/244 (16%)
 Frame = +2

Query: 50  TLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSG 109
           T  GH   ++      ++    + + D    IWD+    ++     +   V +  ++  G
Sbjct: 158 TFEGHKGAVWGATLNREATRAATGAADFSAKIWDAEKGEELQTFSHKHI-VKSVDFSHDG 334

Query: 110 NYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQ-IVTSSGDTTCAL 168
             +  G  + +  +++L   +      +  AGHT  +    FL D + I+++S D T  L
Sbjct: 335 TALLTGSNEKLLKVFDLVNTDAE---PKSFAGHTSNIKGALFLSDGKRIISASDDKTVRL 505

Query: 169 WDIEXXXXXXXXXXXXXDVMSLSLAPDT-------------------------------- 196
           W +E                SL+L+PD                                 
Sbjct: 506 WSLETCQEVQQLTFDTPPT-SLTLSPDKNTIIVTHSQNIAFYQADTLREMKKFEAEAPIS 682

Query: 197 --------RLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDA 248
                   R FV+G  D     +D   G   ++F GH   ++ + F P+G  +A+GS+D 
Sbjct: 683 SASLHQSERFFVAGGEDFKMYKFDYETGKEIESFKGHFGPVHCVRFSPDGELYASGSEDG 862

Query: 249 TCRL 252
           T RL
Sbjct: 863 TLRL 874

 Score = 53.5 bits (127), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 34/121 (28%), Positives = 57/121 (47%), Gaps = 1/121 (0%)
 Frame = +2

Query: 221 TFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSK 280
           TF GH+  +            ATG+ D + +++D    +EL T+SH +I   + SV FS 
Sbjct: 158 TFEGHKGAVWGATLNREATRAATGAADFSAKIWDAEKGEELQTFSHKHI---VKSVDFSH 328

Query: 281 SGRLLLAGYDDFNCNVWDALKAD-RAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIW 339
            G  LL G ++    V+D +  D      AGH + +       DG  + + S D  +++W
Sbjct: 329 DGTALLTGSNEKLLKVFDLVNTDAEPKSFAGHTSNIKGALFLSDGKRIISASDDKTVRLW 508

Query: 340 N 340
           +
Sbjct: 509 S 511

 Score = 37.7 bits (86), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 33/168 (19%), Positives = 60/168 (35%)
 Frame = +2

Query: 49  RTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPS 108
           ++  GH + I    + +D + ++SAS D  + +W   T  +V  +   +    +   +P 
Sbjct: 407 KSFAGHTSNIKGALFLSDGKRIISASDDKTVRLWSLETCQEVQQLTFDTP-PTSLTLSPD 583

Query: 109 GNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTTCAL 168
            N +      NI   Y   T    +R  ++        S      +   V    D     
Sbjct: 584 KNTIIVTHSQNIA-FYQADT----LREMKKFEAEAPISSASLHQSERFFVAGGEDFKMYK 748

Query: 169 WDIEXXXXXXXXXXXXXDVMSLSLAPDTRLFVSGACDASAKLWDVREG 216
           +D E              V  +  +PD  L+ SG+ D + +LW    G
Sbjct: 749 FDYETGKEIESFKGHFGPVHCVRFSPDGELYASGSEDGTLRLWQTTIG 892
>19949
          Length = 903

 Score = 61.6 bits (148), Expect = 4e-10,   Method: Compositional matrix adjust.
 Identities = 43/155 (27%), Positives = 69/155 (44%), Gaps = 1/155 (0%)
 Frame = +2

Query: 187 VMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSD 246
           V SL   P      SG+ D + KLWD+R   C  T+ GH   +  + F P+G   A+ S+
Sbjct: 2   VKSLDFHPYGAYTASGSMDCNVKLWDIRRKGCIYTYKGHTGCVCCLRFSPDGRWIASASE 181

Query: 247 DATCRLFDLRADQELMTYS-HDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRA 305
           D   +L+DL A + L     H +    + ++ F     LL +G  D     WD       
Sbjct: 182 DGLVKLWDLTAGKLLTDLKLHRD---AVNTIEFHPHEFLLASGSADRTVKFWDLETFQLI 352

Query: 306 GVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
                  N +  +    DG+ + +GS D+ LK+++
Sbjct: 353 STTEPEANSIRSILFHPDGVCLYSGSKDT-LKVYH 454

 Score = 37.4 bits (85), Expect = 0.009,   Method: Compositional matrix adjust.
 Identities = 21/79 (26%), Positives = 36/79 (45%)
 Frame = +2

Query: 50  TLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSG 109
           T +GH   +  + +  D R + SAS+DG + +WD      +  + L    V T  + P  
Sbjct: 104 TYKGHTGCVCCLRFSPDGRWIASASEDGLVKLWDLTAGKLLTDLKLHRDAVNTIEFHPHE 283

Query: 110 NYVACGGLDNICSIYNLKT 128
             +A G  D     ++L+T
Sbjct: 284 FLLASGSADRTVKFWDLET 340

 Score = 32.3 bits (72), Expect = 0.26,   Method: Compositional matrix adjust.
 Identities = 27/135 (20%), Positives = 51/135 (37%), Gaps = 1/135 (0%)
 Frame = +2

Query: 72  SASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTREG 131
           S S D  + +WD      ++     +  V    ++P G ++A    D +  +++L     
Sbjct: 44  SGSMDCNVKLWDIRRKGCIYTYKGHTGCVCCLRFSPDGRWIASASEDGLVKLWDLTAG-- 217

Query: 132 NVRVSRELAGHTGYLSCCRFLDDNQIVTS-SGDTTCALWDIEXXXXXXXXXXXXXDVMSL 190
             ++  +L  H   ++   F     ++ S S D T   WD+E              + S+
Sbjct: 218 --KLLTDLKLHRDAVNTIEFHPHEFLLASGSADRTVKFWDLETFQLISTTEPEANSIRSI 391

Query: 191 SLAPDTRLFVSGACD 205
              PD     SG+ D
Sbjct: 392 LFHPDGVCLYSGSKD 436
>02960
          Length = 1577

 Score = 57.8 bits (138), Expect = 6e-09,   Method: Compositional matrix adjust.
 Identities = 44/160 (27%), Positives = 77/160 (48%), Gaps = 7/160 (4%)
 Frame = +2

Query: 139  LAGHTGYLSCCRFLDDNQIVTSSGDTTCALWDIEXXXXXXXXXXXXXDVMSLSLAPDTRL 198
            L+GH   +S  R+LD +++VTSS D +  LWD+               V+ ++ +P + +
Sbjct: 947  LSGHAEAVSAVRWLDPHRVVTSSWDHSLRLWDLHTAQQTSLIQGSKA-VLDVAYSPLSHM 1123

Query: 199  FVSGACDASAKLWDVR--EG-MCRQTFTGHESDINAICFFPN-GNAFATGSDDATCRLFD 254
             ++G+ D   +L D R  EG   +  FT H   +  + + P   + F +GS D   +L+D
Sbjct: 1124 LITGSADRHVRLVDPRCSEGETVKCAFTSHTGWVTGVDWSPTREHLFLSGSYDNVLKLWD 1303

Query: 255  LRADQEL---MTYSHDNIICGITSVSFSKSGRLLLAGYDD 291
             R+ +     M +  D I+    +V +S    LL  G D+
Sbjct: 1304 TRSPKATLYDMNWHEDRIL----AVDWSIPELLLSGGVDN 1411

 Score = 40.0 bits (92), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 27/104 (25%), Positives = 46/104 (44%), Gaps = 6/104 (5%)
 Frame = +2

Query: 243 TGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRL--LLAGYDDFNCNVW--- 297
           +GS D T RL+  + +  +    H + +  +  +   +S  +   + G  D    VW   
Sbjct: 530 SGSYDNTVRLWSTKGEAIMTIPGHTSPVKCVAWIKHDESSGVSTFVTGSHDQTALVWQWQ 709

Query: 298 -DALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
            +  + D      GH   V C+ V+ D   + TGSWD  LK+W+
Sbjct: 710 RETNEVDCRLSCRGHAASVDCVAVSPDSQQMCTGSWDKMLKLWS 841
>10162
          Length = 1629

 Score = 56.6 bits (135), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 63/294 (21%), Positives = 117/294 (39%), Gaps = 13/294 (4%)
 Frame = +3

Query: 58  IYAMHWGTDSRLLVSASQDGKLIIWD--SYTTNKVHAIPLRSSWVMTCAYAPSGNYVACG 115
           I  + W   + +L++ +Q G++ +W   S   +K+  +       +     P+G YV  G
Sbjct: 36  ITWLQWHGGAHVLLAGTQGGEVWLWQVPSQDYSKMKMLQSHGQPSLCGKILPNGKYVCVG 215

Query: 116 GLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTTCALWDIEXXX 175
             D +  +++LKT           A HT   S    + + ++   +          +   
Sbjct: 216 YSDGVVKLWDLKTGT---------AVHTWQHS---VMPEEEMPERNSSDE-----EDGEE 344

Query: 176 XXXXXXXXXXDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFT--------GHES 227
                      ++ +  + D  L +SG  DA+AK+++V  G     F           ++
Sbjct: 345 VEVEREEDTVAILCVDCSADNALIMSGCADATAKVFNVSSGKLXSAFNCAASQDSQDKDN 524

Query: 228 DINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLA 287
            + ++ F P     AT ++  + +++DL       ++ H   +C +    +S S  LL  
Sbjct: 525 SVESVAFCPVSPYAATATNSGSVQVWDLPTSVARHSFQHPEGVCKL---QWSSSTALLYT 695

Query: 288 GYDDFNCNVWDALKADRAGVLAGHDNRVSCL---GVTDDGMAVATGSWDSFLKI 338
              D    VWDA       VL GH  R SC+    VT DG  + +GS D   ++
Sbjct: 696 ACLDGVMRVWDARSGASKAVLTGH-ARNSCILDFDVTRDGTCLVSGSEDGTARV 854
>13278
          Length = 870

 Score = 53.5 bits (127), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 31/112 (27%), Positives = 57/112 (50%), Gaps = 1/112 (0%)
 Frame = +1

Query: 194 PDTRLFVSGAC-DASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRL 252
           P+T L ++ A  D++ +LW+V  G+C  T T H+  + ++ F P+G   A+GS D    +
Sbjct: 103 PNTSLILASASFDSTVRLWEVERGLCLHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHI 282

Query: 253 FDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADR 304
           ++++    + +Y       GI  V ++  G  + A   D +  V D  K D+
Sbjct: 283 WNVQTGSLVHSYKGTG---GIFEVCWNHRGDKVGASASDGSVFVLDLRK*DK 429

 Score = 47.4 bits (111), Expect = 9e-06,   Method: Compositional matrix adjust.
 Identities = 24/100 (24%), Positives = 46/100 (46%)
 Frame = +1

Query: 157 IVTSSGDTTCALWDIEXXXXXXXXXXXXXDVMSLSLAPDTRLFVSGACDASAKLWDVREG 216
           + ++S D+T  LW++E              V S++ +PD +   SG+ D    +W+V+ G
Sbjct: 121 LASASFDSTVRLWEVERGLCLHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNVQTG 300

Query: 217 MCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLR 256
               ++ G    I  +C+   G+     + D +  + DLR
Sbjct: 301 SLVHSYKG-TGGIFEVCWNHRGDKVGASASDGSVFVLDLR 417

 Score = 37.4 bits (85), Expect = 0.009,   Method: Compositional matrix adjust.
 Identities = 24/81 (29%), Positives = 39/81 (48%), Gaps = 9/81 (11%)
 Frame = +1

Query: 57  KIYAMHW-----GTD----SRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAP 107
           +IY + W     GT     S +L SAS D  + +W+      +H +      V + A++P
Sbjct: 55  EIYTIKWSPTGPGTSNPNTSLILASASFDSTVRLWEVERGLCLHTLTKHQEPVYSVAFSP 234

Query: 108 SGNYVACGGLDNICSIYNLKT 128
            G Y+A G  D    I+N++T
Sbjct: 235 DGKYLASGSFDKCVHIWNVQT 297

 Score = 27.7 bits (60), Expect = 6.7,   Method: Compositional matrix adjust.
 Identities = 14/44 (31%), Positives = 23/44 (52%)
 Frame = +1

Query: 49  RTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHA 92
            TL  H   +Y++ +  D + L S S D  + IW+  T + VH+
Sbjct: 184 HTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNVQTGSLVHS 315
>01249
          Length = 1743

 Score = 50.4 bits (119), Expect = 9e-07,   Method: Compositional matrix adjust.
 Identities = 41/137 (29%), Positives = 63/137 (45%), Gaps = 16/137 (11%)
 Frame = -1

Query: 220  QTFTGHESDINAICFFPNGNA--FATGSDDATCRLFDLRADQELMTYSHDNIICGITSVS 277
            +T   H   I  +     G A   A+ S D TC+L+D+ +   L T  ++    G+  + 
Sbjct: 1230 RTINAHSEPITGLHVGCGGPAARVASSSSDGTCKLWDMLSGALLRTMVYET---GVGCLI 1060

Query: 278  FSKSGRLLLAGYD--DFNCN----------VWDALKADRAG--VLAGHDNRVSCLGVTDD 323
              K    LLAG D  D  C+          V+ +    +AG  VL GH + V+CL  + D
Sbjct: 1059 MDKQEHFLLAGLDNGDILCSPLFGQISQSEVFVSKHTTKAGERVLQGHSDAVTCLAFSSD 880

Query: 324  GMAVATGSWDSFLKIWN 340
            G  +A+GS +  + IWN
Sbjct: 879  GQRLASGSQNGKVIIWN 829

 Score = 34.3 bits (77), Expect = 0.069,   Method: Compositional matrix adjust.
 Identities = 14/36 (38%), Positives = 23/36 (63%)
 Frame = -1

Query: 48  RRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWD 83
            R L+GH   +  + + +D + L S SQ+GK+IIW+
Sbjct: 936 ERVLQGHSDAVTCLAFSSDGQRLASGSQNGKVIIWN 829
>02090
          Length = 1841

 Score = 50.4 bits (119), Expect = 9e-07,   Method: Compositional matrix adjust.
 Identities = 39/151 (25%), Positives = 65/151 (43%)
 Frame = -3

Query: 189  SLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDA 248
            +L+++PD ++  S   D +  +WD+      + F GH    + I   P+G    TG  D 
Sbjct: 1611 ALAISPDGKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISPDGTKLWTGGLDN 1432

Query: 249  TCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVL 308
            T R +DLR  ++L  +   +    I S+ +  +G  L  G +  N  V    K D+   L
Sbjct: 1431 TVRSWDLREGRQLQQH---DFSSQIFSLGYCPTGEWLAVGMESSNVEVLHHSKPDKYQ-L 1264

Query: 309  AGHDNRVSCLGVTDDGMAVATGSWDSFLKIW 339
              H++ V  L     G    +   D+ L  W
Sbjct: 1263 HLHESCVLSLKFAYCGKWFVSTGKDNLLNAW 1171

 Score = 34.7 bits (78), Expect = 0.055,   Method: Compositional matrix adjust.
 Identities = 17/66 (25%), Positives = 32/66 (48%)
 Frame = -3

Query: 275  SVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDS 334
            +++ S  G++  +   D N  VWD           GH +  SC+ ++ DG  + TG  D+
Sbjct: 1611 ALAISPDGKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISPDGTKLWTGGLDN 1432

Query: 335  FLKIWN 340
             ++ W+
Sbjct: 1431 TVRSWD 1414

 Score = 33.9 bits (76), Expect = 0.092,   Method: Compositional matrix adjust.
 Identities = 25/97 (25%), Positives = 38/97 (39%)
 Frame = -3

Query: 46   RTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAY 105
            R +  L       YA+    D ++  S   DG + +WD +    V      +        
Sbjct: 1653 RIKAELTSSAPACYALAISPDGKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGASCIDI 1474

Query: 106  APSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGH 142
            +P G  +  GGLDN    ++L  REG     R+L  H
Sbjct: 1473 SPDGTKLWTGGLDNTVRSWDL--REG-----RQLQQH 1384

 Score = 32.0 bits (71), Expect = 0.41,   Method: Compositional matrix adjust.
 Identities = 31/130 (23%), Positives = 60/130 (46%), Gaps = 3/130 (2%)
 Frame = -3

Query: 45   MRTRRTLRGH--LAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMT 102
            +R  R L+ H   ++I+++ +      L    +   + +      +K + + L  S V++
Sbjct: 1413 LREGRQLQQHDFSSQIFSLGYCPTGEWLAVGMESSNVEVLHHSKPDK-YQLHLHESCVLS 1237

Query: 103  CAYAPSGNYVACGGLDNICSIYNLKTREG-NVRVSRELAGHTGYLSCCRFLDDNQIVTSS 161
              +A  G +    G DN+ + +  +T  G ++  S+E    +  LSC    DD  IVT S
Sbjct: 1236 LKFAYCGKWFVSTGKDNLLNAW--RTPYGASIFQSKE---SSSVLSCDIAADDKYIVTGS 1072

Query: 162  GDTTCALWDI 171
            GD    L+++
Sbjct: 1071 GDKKATLYEV 1042
>03395
          Length = 2795

 Score = 49.3 bits (116), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 41/168 (24%), Positives = 67/168 (39%), Gaps = 2/168 (1%)
 Frame = +2

Query: 51  LRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGN 110
           ++ H  K+ A+   T+ R  VSAS DG  IIWD   TN    I L ++      +     
Sbjct: 134 MKEHKGKVTAIQIHTNDRCCVSASTDGSTIIWD-LITNTRSQIVLANTLFKCVCFGGKDL 310

Query: 111 YVACGGLDNICSIYNLKTREGNVRVSRELAG-HTGYLSCCRFLDDNQIVTSSG-DTTCAL 168
           ++   G D+    + +    G+  + REL G  TG ++      D Q + + G D+   L
Sbjct: 311 HILTSGTDHKIGYWEV----GDGGLLRELEGSQTGAINTIDIDRDGQTILTGGEDSLLKL 478

Query: 169 WDIEXXXXXXXXXXXXXDVMSLSLAPDTRLFVSGACDASAKLWDVREG 216
           W                 +    + P+    VSG  D +  +W   +G
Sbjct: 479 WRYNEGEVTHTGIGHSNQITKARICPNRHYIVSGGEDGALHIWKFPDG 622

 Score = 34.3 bits (77), Expect = 0.075,   Method: Compositional matrix adjust.
 Identities = 29/154 (18%), Positives = 60/154 (38%)
 Frame = +2

Query: 187 VMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSD 246
           V ++ +  + R  VS + D S  +WD+      Q    + +    +CF        T   
Sbjct: 155 VTAIQIHTNDRCCVSASTDGSTIIWDLITNTRSQIVLAN-TLFKCVCFGGKDLHILTSGT 331

Query: 247 DATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAG 306
           D     +++  D  L+     +    I ++   + G+ +L G +D    +W   + +   
Sbjct: 332 DHKIGYWEV-GDGGLLRELEGSQTGAINTIDIDRDGQTILTGGEDSLLKLWRYNEGEVTH 508

Query: 307 VLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
              GH N+++   +  +   + +G  D  L IW 
Sbjct: 509 TGIGHSNQITKARICPNRHYIVSGGEDGALHIWK 610
>12574
          Length = 521

 Score = 48.5 bits (114), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 29/119 (24%), Positives = 51/119 (42%), Gaps = 1/119 (0%)
 Frame = +3

Query: 128 TREGNVRVSRELAGHTGYLSCCRFLDDNQ-IVTSSGDTTCALWDIEXXXXXXXXXXXXXD 186
           T++    +   LAGHT  LS  +F  +   + +SS D    +W                 
Sbjct: 141 TQKPTYTLKFTLAGHTKALSAVKFSPNGDWLASSSADKLIKIWGAYDGKFEKTIAGHKLG 320

Query: 187 VMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGS 245
           +  ++ + D++L  S + D + K+W+   G C +T  GH + +    F P  N   +GS
Sbjct: 321 LSDVAWSSDSKLLCSASDDKTLKIWEFSTGKCMKTLKGHSNYVFCCNFNPQSNLIVSGS 497

 Score = 46.2 bits (108), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 24/77 (31%), Positives = 38/77 (49%)
 Frame = +3

Query: 41  GRIQMRTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWV 100
           G    +  +T+ GH   +  + W +DS+LL SAS D  L IW+  T   +  +   S++V
Sbjct: 270 GAYDGKFEKTIAGHKLGLSDVAWSSDSKLLCSASDDKTLKIWEFSTGKCMKTLKGHSNYV 449

Query: 101 MTCAYAPSGNYVACGGL 117
             C + P  N +  G L
Sbjct: 450 FCCNFNPQSNLIVSGSL 500

 Score = 45.4 bits (106), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 28/116 (24%), Positives = 52/116 (44%), Gaps = 3/116 (2%)
 Frame = +3

Query: 219 RQTFTGHESDINAICFFPNGNAFATGSDDATCRL---FDLRADQELMTYSHDNIICGITS 275
           + T  GH   ++A+ F PNG+  A+ S D   ++   +D + ++ +  +       G++ 
Sbjct: 165 KFTLAGHTKALSAVKFSPNGDWLASSSADKLIKIWGAYDGKFEKTIAGHK-----LGLSD 329

Query: 276 VSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGS 331
           V++S   +LL +  DD    +W+         L GH N V C         + +GS
Sbjct: 330 VAWSSDSKLLCSASDDKTLKIWEFSTGKCMKTLKGHSNYVFCCNFNPQSNLIVSGS 497

 Score = 36.2 bits (82), Expect = 0.017,   Method: Compositional matrix adjust.
 Identities = 31/152 (20%), Positives = 57/152 (37%)
 Frame = +3

Query: 9   QEAEQLKNQIRDARKACADATLSQITNNIDPVGRIQMRTRRTLRGHLAKIYAMHWGTDSR 68
           +E+        D + A A AT    ++      +     + TL GH   + A+ +  +  
Sbjct: 57  EESRGAGGDTADGKHAPASATSGTKSSATQ---KPTYTLKFTLAGHTKALSAVKFSPNGD 227

Query: 69  LLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKT 128
            L S+S D  + IW +Y       I      +   A++     +     D    I+   T
Sbjct: 228 WLASSSADKLIKIWGAYDGKFEKTIAGHKLGLSDVAWSSDSKLLCSASDDKTLKIWEFST 407

Query: 129 REGNVRVSRELAGHTGYLSCCRFLDDNQIVTS 160
                +  + L GH+ Y+ CC F   + ++ S
Sbjct: 408 G----KCMKTLKGHSNYVFCCNFNPQSNLIVS 491

 Score = 33.5 bits (75), Expect = 0.12,   Method: Compositional matrix adjust.
 Identities = 16/83 (19%), Positives = 38/83 (45%), Gaps = 1/83 (1%)
 Frame = +3

Query: 189 SLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDA 248
           ++  +P+     S + D   K+W   +G   +T  GH+  ++ + +  +     + SDD 
Sbjct: 201 AVKFSPNGDWLASSSADKLIKIWGAYDGKFEKTIAGHKLGLSDVAWSSDSKLLCSASDDK 380

Query: 249 TCRLFDLRADQELMTYS-HDNII 270
           T ++++    + + T   H N +
Sbjct: 381 TLKIWEFSTGKCMKTLKGHSNYV 449

 Score = 29.6 bits (65), Expect = 1.7,   Method: Compositional matrix adjust.
 Identities = 19/67 (28%), Positives = 31/67 (46%)
 Frame = +3

Query: 273 ITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSW 332
           +++V FS +G  L +   D    +W A        +AGH   +S +  + D   + + S 
Sbjct: 195 LSAVKFSPNGDWLASSSADKLIKIWGAYDGKFEKTIAGHKLGLSDVAWSSDSKLLCSASD 374

Query: 333 DSFLKIW 339
           D  LKIW
Sbjct: 375 DKTLKIW 395
>37180
          Length = 681

 Score = 46.2 bits (108), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 22/64 (34%), Positives = 36/64 (56%), Gaps = 1/64 (1%)
 Frame = +1

Query: 194 PDTRLFVSGACDASAKLWDVRE-GMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRL 252
           P  RL V+ + D + +LWD R+  +    F GH   + +   F +G+   +GSDD T R+
Sbjct: 49  PTQRLVVTSSKDMTFRLWDFRDSALLVNVFQGHTQPVTS-AVFASGDKVVSGSDDRTVRV 225

Query: 253 FDLR 256
           +D+R
Sbjct: 226 WDMR 237

 Score = 31.2 bits (69), Expect = 0.71,   Method: Compositional matrix adjust.
 Identities = 18/77 (23%), Positives = 37/77 (48%)
 Frame = +1

Query: 51  LRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGN 110
           L GH  ++  +H     RL+V++S+D    +WD   +  +  +    +  +T A   SG+
Sbjct: 7   LNGHDQELSDVHAHPTQRLVVTSSKDMTFRLWDFRDSALLVNVFQGHTQPVTSAVFASGD 186

Query: 111 YVACGGLDNICSIYNLK 127
            V  G  D    +++++
Sbjct: 187 KVVSGSDDRTVRVWDMR 237

 Score = 28.5 bits (62), Expect = 4.2,   Method: Compositional matrix adjust.
 Identities = 16/58 (27%), Positives = 26/58 (44%)
 Frame = +1

Query: 157 IVTSSGDTTCALWDIEXXXXXXXXXXXXXDVMSLSLAPDTRLFVSGACDASAKLWDVR 214
           +VTSS D T  LWD                 ++ ++       VSG+ D + ++WD+R
Sbjct: 64  VVTSSKDMTFRLWDFRDSALLVNVFQGHTQPVTSAVFASGDKVVSGSDDRTVRVWDMR 237
>01327
          Length = 2215

 Score = 45.8 bits (107), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 45/218 (20%), Positives = 83/218 (38%), Gaps = 9/218 (4%)
 Frame = +3

Query: 132 NVRVSRELAGHTGYLS-CCRFLDDNQIVTSSGDTTCALWDIEXXXXXXXXXXXXXDVMSL 190
           N R+     GH   ++  C     N + ++S D T  +W                 V ++
Sbjct: 132 NGRLEDRWTGHDREITKVCYGASCNGMFSASRDKTIKMWQRGNSHSIRDFIGHDMVVTAI 311

Query: 191 SLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATC 250
            L  D  L  SG+ D + ++WDV  G C +     ++ +  + + P  +      +D   
Sbjct: 312 HLNTDNTLLCSGSRDNTVRIWDVETGACLRQNNIPQNLVTDVKWLPGSHLIIQAGEDKEV 491

Query: 251 RLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCN-----VWDALKADRA 305
           R++D R    + +++    I    S   +  G+  L   + F  N     +W        
Sbjct: 492 RIYDSRTLGIVRSFTKKQYI--QMSCDVTADGQFCLTCSNGFGGNGCEATLWQLSDGSIQ 665

Query: 306 GVLAGHDNRV-SCLGV--TDDGMAVATGSWDSFLKIWN 340
               GH   + +CL +    D   +AT S D  +++WN
Sbjct: 666 NEFKGHREAIEACLFLPSNQDMTLIATASRDCSVRVWN 779

 Score = 44.7 bits (104), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 28/110 (25%), Positives = 52/110 (47%), Gaps = 1/110 (0%)
 Frame = +3

Query: 191 SLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATC 250
           S+ P   L +SG+ D S  L+D + G     +TGH+ +I  +C+  + N   + S D T 
Sbjct: 66  SIQPG--LCLSGSKDKSVVLYDYQNGRLEDRWTGHDREITKVCYGASCNGMFSASRDKTI 239

Query: 251 RLFDLRADQELMTY-SHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDA 299
           +++       +  +  HD +   +T++  +    LL +G  D    +WD 
Sbjct: 240 KMWQRGNSHSIRDFIGHDMV---VTAIHLNTDNTLLCSGSRDNTVRIWDV 380

 Score = 44.7 bits (104), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 47/210 (22%), Positives = 74/210 (35%), Gaps = 3/210 (1%)
 Frame = +3

Query: 49  RTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPS 108
           R   GH   + A+H  TD+ LL S S+D  + IWD  T   +    +  + V    + P 
Sbjct: 273 RDFIGHDMVVTAIHLNTDNTLLCSGSRDNTVRIWDVETGACLRQNNIPQNLVTDVKWLPG 452

Query: 109 GNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTTCAL 168
            + +   G D    IY+ +T    + + R           C    D Q        TC+ 
Sbjct: 453 SHLIIQAGEDKEVRIYDSRT----LGIVRSFTKKQYIQMSCDVTADGQFC-----LTCS- 602

Query: 169 WDIEXXXXXXXXXXXXXDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESD 228
                                         F    C+A+  LW + +G  +  F GH   
Sbjct: 603 ----------------------------NGFGGNGCEAT--LWQLSDGSIQNEFKGHREA 692

Query: 229 INAICFFPNGN---AFATGSDDATCRLFDL 255
           I A  F P+       AT S D + R++++
Sbjct: 693 IEACLFLPSNQDMTLIATASRDCSVRVWNM 782
>03156
          Length = 1014

 Score = 45.4 bits (106), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 40/194 (20%), Positives = 75/194 (38%), Gaps = 8/194 (4%)
 Frame = +1

Query: 155 NQIVTSSGDTTCALWDIEXXXXXXXXXXXXXDVMSLSLAPDTRLFVSGACDASAKLWDVR 214
           N + ++S D T  +W                 V ++ L  D  L  SG+ D + ++WDV 
Sbjct: 94  NGMFSASRDKTIKMWQRGNSHSIRDFIGHDMVVTAIHLNTDNTLLCSGSRDNTVRIWDVE 273

Query: 215 EGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGIT 274
            G C +     ++ +  + + P  +      +D   R++D R    + +++    I    
Sbjct: 274 TGACLRQNNIPQNLVTDVKWLPGSHLIIQAGEDKEVRIYDSRTLGIVRSFTKKQYI--QM 447

Query: 275 SVSFSKSGRLLLAGYDDFNCN-----VWDALKADRAGVLAGHDNRV-SCLGV--TDDGMA 326
           S   +  G+  L   + F  N     +W            GH   + +CL +    D   
Sbjct: 448 SCDVTADGQFCLTCSNGFGGNGCEATLWQLSDGSIQNEFKGHREAIEACLFLPSNQDMTL 627

Query: 327 VATGSWDSFLKIWN 340
           +AT S D  +++WN
Sbjct: 628 IATASRDCSVRVWN 669

 Score = 44.7 bits (104), Expect = 6e-05,   Method: Compositional matrix adjust.
 Identities = 48/210 (22%), Positives = 75/210 (35%), Gaps = 3/210 (1%)
 Frame = +1

Query: 49  RTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPS 108
           R   GH   + A+H  TD+ LL S S+D  + IWD  T   +    +  + V    + P 
Sbjct: 163 RDFIGHDMVVTAIHLNTDNTLLCSGSRDNTVRIWDVETGACLRQNNIPQNLVTDVKWLPG 342

Query: 109 GNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTTCAL 168
            + +   G D    IY+ +T                 L   R     Q +  S D T   
Sbjct: 343 SHLIIQAGEDKEVRIYDSRT-----------------LGIVRSFTKKQYIQMSCDVT--- 462

Query: 169 WDIEXXXXXXXXXXXXXDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESD 228
                                L+ +     F    C+A+  LW + +G  +  F GH   
Sbjct: 463 ---------------ADGQFCLTCSNG---FGGNGCEAT--LWQLSDGSIQNEFKGHREA 582

Query: 229 INAICFFPNGN---AFATGSDDATCRLFDL 255
           I A  F P+       AT S D + R++++
Sbjct: 583 IEACLFLPSNQDMTLIATASRDCSVRVWNM 672

 Score = 33.9 bits (76), Expect = 0.092,   Method: Compositional matrix adjust.
 Identities = 19/87 (21%), Positives = 39/87 (44%), Gaps = 1/87 (1%)
 Frame = +1

Query: 214 REGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTY-SHDNIICG 272
           + G     +TGH+ +I  +C+  + N   + S D T +++       +  +  HD +   
Sbjct: 19  KMGRLEDRWTGHDREITKVCYGASCNGMFSASRDKTIKMWQRGNSHSIRDFIGHDMV--- 189

Query: 273 ITSVSFSKSGRLLLAGYDDFNCNVWDA 299
           +T++  +    LL +G  D    +WD 
Sbjct: 190 VTAIHLNTDNTLLCSGSRDNTVRIWDV 270
>01805
          Length = 2124

 Score = 44.3 bits (103), Expect = 7e-05,   Method: Compositional matrix adjust.
 Identities = 59/270 (21%), Positives = 109/270 (40%), Gaps = 35/270 (12%)
 Frame = -1

Query: 64  GTDSRLLVSASQDGKLIIWDSYTTNK------VH------AIPLRSSWVMTCAY--APSG 109
            TD+ +L    Q G L + D Y  N+      VH      + PL   W+    Y  AP G
Sbjct: 897 ATDNLILCGRCQ-GDLSVLDVYVYNEDNNQLYVHHDYLLSSFPLALEWLNFDGYDNAP-G 724

Query: 110 NYVACGGLDNICSIYNLKTREG----------------NVRVSRELAGHTGYLSCCRFLD 153
           N+VA G ++ +  I++L   E                  ++    + GHT  +    +  
Sbjct: 723 NFVAIGSMEPVIEIWDLDIMESVGPTLTLGSKPKKTKKKMKQKESVTGHTQAVLDLSWNR 544

Query: 154 DNQ--IVTSSGDTTCALWDIEXXXXXXXXXXXXXDVMSLSLAP-DTRLFVSGACDASAKL 210
           + +  + ++S DTT ALWD+              +V   +  P + +  ++G+ D + K+
Sbjct: 543 NARHVLASASADTTVALWDLSEGKMAMNFTQHSREVQCCNWHPQEEQTLLTGSFDNTVKV 364

Query: 211 WDVREG-MCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTY-SHDN 268
            D R    C +++T       A+    N       +D      FD+R ++ + +  +H +
Sbjct: 363 VDCRSAETCHKSWTVEGEVEKAVWNHHNPLQLLACTDKGMVYCFDIRHEKPVFSVGAHSS 184

Query: 269 IICGITSVSFSKSGRLLLAGYDDFNCNVWD 298
            + G+     S+   L++   +D    VWD
Sbjct: 183 CVTGV--CLSSQIPGLMITTSEDKTMKVWD 100
>15780
          Length = 735

 Score = 42.7 bits (99), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 32/115 (27%), Positives = 52/115 (45%), Gaps = 1/115 (0%)
 Frame = -1

Query: 197 RLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDL- 255
           +   +   D +  +WD+  G      T H   + A+CF  +G   A+G  D + RL+DL 
Sbjct: 735 KYLSTAGADHTVIVWDIASGTAVAHLTAHTDTVYALCFSRDGTVLASGGMDNSIRLWDLA 556

Query: 256 RADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAG 310
           R  +E    +  N+    +S+S + +  LLL  Y   +  V+  L   R  VL G
Sbjct: 555 RVMEEQDPETDSNV---PSSLSVNTNPALLLGTYYTKSSPVF-GLHFTRRNVLLG 403

 Score = 29.3 bits (64), Expect = 2.7,   Method: Compositional matrix adjust.
 Identities = 15/59 (25%), Positives = 29/59 (49%)
 Frame = -1

Query: 68  RLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNL 126
           + L +A  D  +I+WD  +   V  +   +  V    ++  G  +A GG+DN   +++L
Sbjct: 735 KYLSTAGADHTVIVWDIASGTAVAHLTAHTDTVYALCFSRDGTVLASGGMDNSIRLWDL 559
>26107
          Length = 1338

 Score = 42.4 bits (98), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 66/292 (22%), Positives = 97/292 (33%), Gaps = 24/292 (8%)
 Frame = -3

Query: 72  SASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTREG 131
           S ++DG +++WDS    K    P                   C  +  +C     +++  
Sbjct: 907 SGARDGHIMLWDSRVNKKREHQP-------------------CSQVHQVCPQSGHQSKPA 785

Query: 132 NVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTTCALWDIEXXXXXXXXXXXXXDVMSLS 191
             R     AG  G       +D  Q V      TC L+                      
Sbjct: 784 KHRRIHRAAGPKG------VMDTQQSV------TCVLYQT-------------------- 701

Query: 192 LAPDTRLFVSGACDASAKLWDVREGMCRQT-----------FTGHESDINAI---CFFP- 236
              D  +  SGA D   K+WD R+     T           + GH   +  I   C  P 
Sbjct: 700 ---DNLIISSGANDGCVKMWDTRKWYTNTTTSLPVPVHTFDYPGHMRRLKGIVTMCMDPW 530

Query: 237 NGNAFATGSDDATCRLF---DLRADQELMTYSHDN----IICGITSVSFSKSGRLLLAGY 289
               F + +D+   R       R  QE +   H N    + C I     S  G+ LL+G 
Sbjct: 529 KSQLFVSYTDNKVYRYQLAGQYREPQEYVYAGHRNDTFFVRCAI-----SPDGKYLLSGS 365

Query: 290 DDFNCNVWDALKAD-RAGVLAGHDNRVSCLG-VTDDGMAVATGSWDSFLKIW 339
                 +W+  K + R   L GH   VS +   + D   +AT S D  L+IW
Sbjct: 364 GRNTGVIWEVDKPNKRPLFLIGHTEDVSAVDWCSTDVCKLATVSDDRSLRIW 209

 Score = 39.7 bits (91), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 39/152 (25%), Positives = 63/152 (41%), Gaps = 3/152 (1%)
 Frame = -3

Query: 153  DDNQIVTSSGDTTCALWDIEXXXXXXXXXXXXXDVMSLSLAPDTRLF-VSGACDASAKLW 211
            +D+Q +T+SGD T ALWD+E              V S++  P +     SGA D    LW
Sbjct: 1054 NDSQCLTASGDQTVALWDVETTTKVTTFIGHKCSVRSVASCPSSPAQCASGARDGHIMLW 875

Query: 212  DVREGMCRQTFTGHE--SDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNI 269
            D R    R+    H+  S ++ +C  P        S  A  R     A  + +  +  ++
Sbjct: 874  DSRVNKKRE----HQPCSQVHQVC--PQS---GHQSKPAKHRRIHRAAGPKGVMDTQQSV 722

Query: 270  ICGITSVSFSKSGRLLLAGYDDFNCNVWDALK 301
             C    V +     ++ +G +D    +WD  K
Sbjct: 721  TC----VLYQTDNLIISSGANDGCVKMWDTRK 638
>12960
          Length = 550

 Score = 42.0 bits (97), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 27/112 (24%), Positives = 51/112 (45%)
 Frame = +2

Query: 187 VMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSD 246
           V ++  + D+R  ++   D S KLW+    +  +T+ GH  ++       + +   +G  
Sbjct: 182 VRAVRFSVDSRYCMTCGSDKSVKLWNPHRELFLKTYIGHGHEVLDAQGSGDNSQICSGGI 361

Query: 247 DATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWD 298
           D T  LFD+ + Q L  Y   +    +  V F++   ++L+G  D     WD
Sbjct: 362 DKTVVLFDVASGQALRKYR--DHAGTVNCVKFNEESTVILSGSLDNTVRAWD 511
>27806
          Length = 419

 Score = 41.2 bits (95), Expect = 6e-04,   Method: Compositional matrix adjust.
 Identities = 17/66 (25%), Positives = 33/66 (50%)
 Frame = -1

Query: 194 PDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLF 253
           P   +  + + D +A+++ +  G C  T+ GH+  +NA+ F P  +   T S D T  ++
Sbjct: 395 PGHPIIGTASADHTARIYSIETGACVLTYGGHQGSVNAVRFHPGQDLVLTASGDHTAHVW 216

Query: 254 DLRADQ 259
             +  Q
Sbjct: 215 RAQFSQ 198
>21105
          Length = 650

 Score = 40.8 bits (94), Expect = 8e-04,   Method: Compositional matrix adjust.
 Identities = 21/71 (29%), Positives = 35/71 (49%), Gaps = 4/71 (5%)
 Frame = +1

Query: 187 VMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGH----ESDINAICFFPNGNAFA 242
           V SL++ P+    +SG+ D S +LW++    C Q  T H    +  I+ + F P     A
Sbjct: 199 VTSLAVDPNGLYLLSGSHDCSIRLWNLDSKTCVQEITSHRKKFDESIHDVAFHPQKPYIA 378

Query: 243 TGSDDATCRLF 253
           +   DA  ++F
Sbjct: 379 SAGADALAKVF 411

 Score = 29.3 bits (64), Expect = 2.5,   Method: Compositional matrix adjust.
 Identities = 15/61 (24%), Positives = 31/61 (50%)
 Frame = +1

Query: 69  LLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKT 128
           + ++A +D  +  +D+ T   +HA+      V + A  P+G Y+  G  D    ++NL +
Sbjct: 106 ITITAHEDRHIRFFDNNTGKLIHAMVAHLDSVTSLAVDPNGLYLLSGSHDCSIRLWNLDS 285

Query: 129 R 129
           +
Sbjct: 286 K 288
>01462
          Length = 995

 Score = 40.0 bits (92), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 18/65 (27%), Positives = 31/65 (47%)
 Frame = +2

Query: 196 TRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDL 255
           TR   +GA D    +WD+  G       GH+  I+ +    +     + S+D T R++D+
Sbjct: 233 TRRLYAGAGDRKIHVWDIEAGQYLNAMEGHKDYIHKVVMKNDAQECVSASEDGTVRMWDI 412

Query: 256 RADQE 260
           R+  E
Sbjct: 413 RSSTE 427

 Score = 37.7 bits (86), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 26/89 (29%), Positives = 43/89 (48%), Gaps = 11/89 (12%)
 Frame = +2

Query: 51  LRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWD-SYTTNKVHAI----------PLRSSW 99
           + GH   I+ +    D++  VSAS+DG + +WD   +T  VH +          PL   W
Sbjct: 311 MEGHKDYIHKVVMKNDAQECVSASEDGTVRMWDIRSSTETVHCLEPSKNELCSRPLLGKW 490

Query: 100 VMTCAYAPSGNYVACGGLDNICSIYNLKT 128
           +   A  P   ++ CGG   + S ++L+T
Sbjct: 491 LRCLALDPEEGWLVCGGGPKL-SAWHLRT 574

 Score = 29.6 bits (65), Expect = 2.0,   Method: Compositional matrix adjust.
 Identities = 18/81 (22%), Positives = 33/81 (40%)
 Frame = +2

Query: 156 QIVTSSGDTTCALWDIEXXXXXXXXXXXXXDVMSLSLAPDTRLFVSGACDASAKLWDVRE 215
           ++   +GD    +WDIE              +  + +  D +  VS + D + ++WD+R 
Sbjct: 239 RLYAGAGDRKIHVWDIEAGQYLNAMEGHKDYIHKVVMKNDAQECVSASEDGTVRMWDIRS 418

Query: 216 GMCRQTFTGHESDINAICFFP 236
               +T    E   N +C  P
Sbjct: 419 ST--ETVHCLEPSKNELCSRP 475

 Score = 29.3 bits (64), Expect = 2.2,   Method: Compositional matrix adjust.
 Identities = 14/58 (24%), Positives = 26/58 (44%)
 Frame = +2

Query: 283 RLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
           R L AG  D   +VWD         + GH + +  + + +D     + S D  +++W+
Sbjct: 236 RRLYAGAGDRKIHVWDIEAGQYLNAMEGHKDYIHKVVMKNDAQECVSASEDGTVRMWD 409
>34005
          Length = 456

 Score = 40.0 bits (92), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 6/110 (5%)
 Frame = +1

Query: 186 DVMSLSLAPDTRLFVSGACDASAKLWDVREGM---CRQTFTGHESDINAICFFPNGN--- 239
           +V  LS +PD     SG+ D S  +WD   GM      T T H++ + A+ + P      
Sbjct: 118 EVCGLSWSPDATFLASGSNDNSVNIWDSTLGMDVPPLHTLTSHQAAVKAVAWCPWQTRML 297

Query: 240 AFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGY 289
           A   G++D   R ++      +      + +C   SV + K  R L++G+
Sbjct: 298 ATGGGTNDRHIRFWNTNTGACVKAVDTQSQVC---SVLWCKEHRELVSGH 438
>03387
          Length = 1891

 Score = 39.7 bits (91), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 34/109 (31%), Positives = 49/109 (44%), Gaps = 5/109 (4%)
 Frame = +1

Query: 198 LFVSGACDASAKLWDVREGMCRQT---FTGHESDINAICFFPNGN-AFATGSDDATCRLF 253
           LF S A D    +WD R     +       H +++N + F P      ATGS D T  L+
Sbjct: 556 LFGSVADDQKLMIWDTRSNTTSKPSHVVDAHTAEVNCLSFNPYSEFILATGSADKTVALW 735

Query: 254 DLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGY-DDFNCNVWDALK 301
           DLR + +L  +S ++    I  V +S     +LA    D   +VWD  K
Sbjct: 736 DLR-NLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLHVWDLSK 879

 Score = 35.4 bits (80), Expect = 0.031,   Method: Compositional matrix adjust.
 Identities = 46/214 (21%), Positives = 79/214 (36%), Gaps = 12/214 (5%)
 Frame = +1

Query: 38  DPVGRIQMRTRRTLRGHLAKIYAMHWGTD-SRLLVSASQDGKLIIWDSYTTNK------V 90
           DP G      R  L+GH  + Y + W  + +  L+SAS D  + +WD  +T +       
Sbjct: 316 DPSGECIPELR--LKGHQKEGYGLSWNPNLNGHLLSASDDHTICLWDINSTQRESRVVDA 489

Query: 91  HAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNV-RVSRELAGHTGYLSCC 149
           H I    + V+        +    G + +   +    TR     + S  +  HT  ++C 
Sbjct: 490 HTIFTGHTSVVEDVAWHLLHESLFGSVADDQKLMIWDTRSNTTSKPSHVVDAHTAEVNCL 669

Query: 150 RFLDDNQIV--TSSGDTTCALWDIEXXXXXXXXXXXXXD-VMSLSLAPDTR-LFVSGACD 205
            F   ++ +  T S D T ALWD+              D +  +  +P    +  S   D
Sbjct: 670 SFNPYSEFILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGTD 849

Query: 206 ASAKLWDVREGMCRQTFTGHESDINAICFFPNGN 239
               +WD+ +    Q     E     + F   G+
Sbjct: 850 RRLHVWDLSKIGEEQLPEDAEDGPPELLFIHGGH 951
>11493
          Length = 535

 Score = 39.3 bits (90), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 24/110 (21%), Positives = 48/110 (43%), Gaps = 3/110 (2%)
 Frame = -2

Query: 145 YLSCCRFLDDNQIVTSSGDTT-CALWDIEXXXX--XXXXXXXXXDVMSLSLAPDTRLFVS 201
           Y+   + L D + +   G+ +  ++WD+                   +L+++PD+++  S
Sbjct: 333 YIRSVKLLPDGRTLIVGGEASNLSIWDLASPTPRIKAELTSAAPACYALAISPDSKVCFS 154

Query: 202 GACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCR 251
              D +  +WD+   +  + F GH    + I   P+G+   TG  D T R
Sbjct: 153 CCSDGNIAVWDLHNEILVRQFQGHTDGASCIDISPDGSRLWTGGLDNTVR 4

 Score = 38.9 bits (89), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 27/156 (17%), Positives = 65/156 (41%), Gaps = 5/156 (3%)
 Frame = -2

Query: 187 VMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTG-----HESDINAICFFPNGNAF 241
           V +++++  T+   +G      K+WD+ +   +   +       ++ I ++   P+G   
Sbjct: 468 VCAVTISNPTKYVYTGG-KGCVKVWDISQPGNKNPVSQLDCLQRDNYIRSVKLLPDGRTL 292

Query: 242 ATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALK 301
             G + +   ++DL +    +     +      +++ S   ++  +   D N  VWD   
Sbjct: 291 IVGGEASNLSIWDLASPTPRIKAELTSAAPACYALAISPDSKVCFSCCSDGNIAVWDLHN 112

Query: 302 ADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLK 337
                   GH +  SC+ ++ DG  + TG  D+ ++
Sbjct: 111 EILVRQFQGHTDGASCIDISPDGSRLWTGGLDNTVR 4

 Score = 30.8 bits (68), Expect = 0.74,   Method: Compositional matrix adjust.
 Identities = 19/74 (25%), Positives = 30/74 (40%)
 Frame = -2

Query: 46  RTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAY 105
           R +  L       YA+    DS++  S   DG + +WD +    V      +        
Sbjct: 234 RIKAELTSAAPACYALAISPDSKVCFSCCSDGNIAVWDLHNEILVRQFQGHTDGASCIDI 55

Query: 106 APSGNYVACGGLDN 119
           +P G+ +  GGLDN
Sbjct: 54  SPDGSRLWTGGLDN 13
>03734
          Length = 1963

 Score = 37.7 bits (86), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 28/129 (21%), Positives = 51/129 (39%), Gaps = 15/129 (11%)
 Frame = -2

Query: 190  LSLAPDTRLFVSGACDASAKLWDVR--EGMCRQTFTGHESD------INAICFFPNGNAF 241
            L++ PD R  VS    +S ++WD+   +G    T    E++         +C   N    
Sbjct: 1143 LAITPDNRYLVSATSVSSLQIWDISDDKGTLLHTVRPEETEEEGRHSFTNLCVSDNSKMA 964

Query: 242  ATGSDDATCRLFDLRADQELMTYSHDNIICGI-------TSVSFSKSGRLLLAGYDDFNC 294
            AT +      L+ +         +   ++C +       T++SF+ + R LL  Y D   
Sbjct: 963  ATSNSGGQVHLYSI---------AEGEVLCKLPALSQQATAISFTXAARTLLVTYSDHKV 811

Query: 295  NVWDALKAD 303
              +D  K +
Sbjct: 810  MEFDVQKEE 784
>29912
          Length = 510

 Score = 37.7 bits (86), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 28/115 (24%), Positives = 51/115 (44%), Gaps = 2/115 (1%)
 Frame = +3

Query: 187 VMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSD 246
           + ++S   +      G      ++WDV +    +T  GH + + ++ +  N    ++GS 
Sbjct: 18  IGAVSWIKEGNYLALGTSTGEVQVWDVTQQKKLRTMAGHAARVGSLSW--NSFIVSSGSR 191

Query: 247 DATCRLFDLR-ADQELMTYS-HDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDA 299
                  D+R AD  + T S H   +CG+    +S  G+ L +G +D    VW A
Sbjct: 192 SGNIHHHDVRVADHHVGTLSGHSQEVCGL---RWSPDGKYLASGANDNLLCVWPA 347

 Score = 35.8 bits (81), Expect = 0.024,   Method: Compositional matrix adjust.
 Identities = 24/90 (26%), Positives = 44/90 (48%), Gaps = 1/90 (1%)
 Frame = +3

Query: 44  QMRTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTT-NKVHAIPLRSSWVMT 102
           Q +  RT+ GH A++ ++ W  +S ++ S S+ G +   D     + V  +   S  V  
Sbjct: 102 QQKKLRTMAGHAARVGSLSW--NSFIVSSGSRSGNIHHHDVRVADHHVGTLSGHSQEVCG 275

Query: 103 CAYAPSGNYVACGGLDNICSIYNLKTREGN 132
             ++P G Y+A G  DN+  ++  +   GN
Sbjct: 276 LRWSPDGKYLASGANDNLLCVWPAQVTGGN 365

 Score = 32.7 bits (73), Expect = 0.22,   Method: Compositional matrix adjust.
 Identities = 20/64 (31%), Positives = 27/64 (42%)
 Frame = +3

Query: 273 ITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSW 332
           I +VS+ K G  L  G       VWD  +  +   +AGH  RV  L            SW
Sbjct: 18  IGAVSWIKEGNYLALGTSTGEVQVWDVTQQKKLRTMAGHAARVGSL------------SW 161

Query: 333 DSFL 336
           +SF+
Sbjct: 162 NSFI 173

 Score = 31.2 bits (69), Expect = 0.57,   Method: Compositional matrix adjust.
 Identities = 14/48 (29%), Positives = 22/48 (45%)
 Frame = +3

Query: 50  TLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRS 97
           TL GH  ++  + W  D + L S + D  L +W +  T      PL +
Sbjct: 243 TLSGHSQEVCGLRWSPDGKYLASGANDNLLCVWPAQVTGGNSTQPLHT 386
>16199
          Length = 694

 Score = 37.4 bits (85), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 14/41 (34%), Positives = 23/41 (56%)
 Frame = +2

Query: 194 PDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICF 234
           PD  +F +G  D+  K+WD++E      F GH+  + +I F
Sbjct: 101 PDGLIFATGTEDSVIKIWDLKERANVANFQGHQGPVTSISF 223

 Score = 32.7 bits (73), Expect = 0.21,   Method: Compositional matrix adjust.
 Identities = 15/48 (31%), Positives = 29/48 (60%)
 Frame = +2

Query: 234 FFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKS 281
           F P+G  FATG++D+  +++DL+    +  +        +TS+SFS++
Sbjct: 95  FHPDGLIFATGTEDSVIKIWDLKERANVANFQGHQ--GPVTSISFSET 232

 Score = 28.1 bits (61), Expect = 5.6,   Method: Compositional matrix adjust.
 Identities = 11/26 (42%), Positives = 17/26 (65%)
 Frame = +2

Query: 315 VSCLGVTDDGMAVATGSWDSFLKIWN 340
           ++C     DG+  ATG+ DS +KIW+
Sbjct: 80  LTCAQFHPDGLIFATGTEDSVIKIWD 157
>19863
          Length = 502

 Score = 37.4 bits (85), Expect = 0.010,   Method: Compositional matrix adjust.
 Identities = 22/89 (24%), Positives = 39/89 (43%)
 Frame = +1

Query: 195 DTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFD 254
           D    VSG+ D S  +WDV  G+ +    GH   +N + F  +     + S+D T R+++
Sbjct: 4   DGLQLVSGSSDMSIVVWDVENGVQKLRLQGHAGWVNDVHFSQDQCWLLSCSNDNTVRIWN 183

Query: 255 LRADQELMTYSHDNIICGITSVSFSKSGR 283
           +    ++          G+     SK G+
Sbjct: 184 IEESDQIPIVMEHKRAQGLKVTKCSKCGK 270
>18981
          Length = 407

 Score = 37.0 bits (84), Expect = 0.011,   Method: Compositional matrix adjust.
 Identities = 32/114 (28%), Positives = 50/114 (43%)
 Frame = -2

Query: 152 LDDNQIVTSSGDTTCALWDIEXXXXXXXXXXXXXDVMSLSLAPDTRLFVSGACDASAKLW 211
           L DN I++++ D T  +W ++             DV  + +    R  VSG+ D +  +W
Sbjct: 394 LLDNMIISAATDRTLRVWCLKNTCLLHTLRGHNDDVECVCIYG--RRVVSGSWDKTLIVW 221

Query: 212 DVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYS 265
           +V  G       GH   I A+  F  G A + GS D   R + L   Q L+T +
Sbjct: 220 EVDTGRPVHQLHGHTEAITAV-QFDEGKAVS-GSADGDVRTWALDTGQCLLTMT 65

 Score = 32.3 bits (72), Expect = 0.30,   Method: Compositional matrix adjust.
 Identities = 20/86 (23%), Positives = 40/86 (46%), Gaps = 3/86 (3%)
 Frame = -2

Query: 198 LFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDL-- 255
           + +S A D + ++W ++      T  GH  D+  +C +  G    +GS D T  ++++  
Sbjct: 382 MIISAATDRTLRVWCLKNTCLLHTLRGHNDDVECVCIY--GRRVVSGSWDKTLIVWEVDT 209

Query: 256 -RADQELMTYSHDNIICGITSVSFSK 280
            R   +L  ++       IT+V F +
Sbjct: 208 GRPVHQLHGHTE-----AITAVQFDE 146

 Score = 28.5 bits (62), Expect = 4.1,   Method: Compositional matrix adjust.
 Identities = 16/57 (28%), Positives = 26/57 (45%)
 Frame = -2

Query: 284 LLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
           ++++   D    VW          L GH++ V C+ +   G  V +GSWD  L +W 
Sbjct: 382 MIISAATDRTLRVWCLKNTCLLHTLRGHNDDVECVCIY--GRRVVSGSWDKTLIVWE 218
>19498
          Length = 903

 Score = 36.2 bits (82), Expect = 0.020,   Method: Compositional matrix adjust.
 Identities = 28/119 (23%), Positives = 48/119 (40%), Gaps = 4/119 (3%)
 Frame = -1

Query: 46  RTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYT-TNKVHAIPLRSSWVMTCA 104
           R+  TLRGH   +  + W      L S S D  +++W++   + +V  I   +  V    
Sbjct: 636 RSVATLRGHAGDVLDLAWSPQDLWLASCSVDNTIVVWNALKFSEQVAVIRGHAGMVKGVT 457

Query: 105 YAPSGNYVACGGLDNICSIYNLKTREGNVRVS---RELAGHTGYLSCCRFLDDNQIVTS 160
           + P G Y+A    D    ++     +    V    +E  G T  L      D N +V++
Sbjct: 456 WDPVGRYLASQSDDKTLRVWRTSDWKEETCVKSCFKECGGTTHVLRLNWSPDGNHVVSA 280

 Score = 35.0 bits (79), Expect = 0.039,   Method: Compositional matrix adjust.
 Identities = 29/139 (20%), Positives = 54/139 (38%), Gaps = 19/139 (13%)
 Frame = -1

Query: 134 RVSRELAGHTGYLSCCRFLDDNQIVTSSG-DTTCALWDI-----------------EXXX 175
           RV  ++  H G ++C R+ ++ + + S G D    +W I                 E   
Sbjct: 813 RVLCQMDSHLGCVNCVRWSENGKFLASGGDDKLIMIWQISRGFGSGKSFGSNVTILEHWR 634

Query: 176 XXXXXXXXXXDVMSLSLAPDTRLFVSGACDASAKLWD-VREGMCRQTFTGHESDINAICF 234
                     DV+ L+ +P      S + D +  +W+ ++         GH   +  + +
Sbjct: 633 SVATLRGHAGDVLDLAWSPQDLWLASCSVDNTIVVWNALKFSEQVAVIRGHAGMVKGVTW 454

Query: 235 FPNGNAFATGSDDATCRLF 253
            P G   A+ SDD T R++
Sbjct: 453 DPVGRYLASQSDDKTLRVW 397
>31864
          Length = 545

 Score = 35.8 bits (81), Expect = 0.025,   Method: Compositional matrix adjust.
 Identities = 35/128 (27%), Positives = 55/128 (42%), Gaps = 17/128 (13%)
 Frame = +2

Query: 142 HTGYLSCCRFLDDNQI-VTSSGDTTCALWDIEXXXXXXXXXXXXXDVMSLSLAPDT-RLF 199
           HTG ++  +   D  + VT+S DTT  L+D E              V S +++P    + 
Sbjct: 47  HTGGINDMQLSKDGTMFVTASKDTTAKLFDSESLMCLKTYKTERP-VNSAAISPILDHVV 223

Query: 200 VSGACDA--------SAKLWDVR-------EGMCRQTFTGHESDINAICFFPNGNAFATG 244
           + G  DA         A  +D R       E   R    GH   IN++ F P+G ++A+G
Sbjct: 224 LGGGQDAMEVTTTSTKAGKFDSRFFHLIYEEEFAR--LKGHFGPINSLAFHPDGKSYASG 397

Query: 245 SDDATCRL 252
            +D   R+
Sbjct: 398 GEDGFVRV 421
>35607
          Length = 475

 Score = 35.8 bits (81), Expect = 0.026,   Method: Compositional matrix adjust.
 Identities = 23/105 (21%), Positives = 44/105 (41%)
 Frame = +2

Query: 193 APDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRL 252
            PD     +G  D + + WD+REG   Q      S I ++ + P G+  A G + +   +
Sbjct: 5   PPDGTKLWTGGLDNTVRSWDLREGRQLQQHD-FSSQIFSLGYCPTGDWLAVGMESSNVEV 181

Query: 253 FDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVW 297
                  +   + H++ +    S+ F+  G+  ++   D   N W
Sbjct: 182 LHHSKPDKYQLHLHESCVL---SLKFAYCGKWFVSTGKDNLLNAW 307

 Score = 32.0 bits (71), Expect = 0.41,   Method: Compositional matrix adjust.
 Identities = 28/104 (26%), Positives = 43/104 (41%)
 Frame = +2

Query: 236 PNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCN 295
           P+G    TG  D T R +DLR  ++L  +   +    I S+ +  +G  L  G +  N  
Sbjct: 8   PDGTKLWTGGLDNTVRSWDLREGRQLQQH---DFSSQIFSLGYCPTGDWLAVGMESSNVE 178

Query: 296 VWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIW 339
           V    K D+   L  H++ V  L     G    +   D+ L  W
Sbjct: 179 VLHHSKPDKY-QLHLHESCVLSLKFAYCGKWFVSTGKDNLLNAW 307

 Score = 30.8 bits (68), Expect = 0.80,   Method: Compositional matrix adjust.
 Identities = 24/82 (29%), Positives = 41/82 (50%), Gaps = 1/82 (1%)
 Frame = +2

Query: 91  HAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTREG-NVRVSRELAGHTGYLSCC 149
           + + L  S V++  +A  G +    G DN+ + +  +T  G ++  S+E    +  LSC 
Sbjct: 206 YQLHLHESCVLSLKFAYCGKWFVSTGKDNLLNAW--RTPYGASIFQSKE---SSSVLSCD 370

Query: 150 RFLDDNQIVTSSGDTTCALWDI 171
              DD  IVT SGD    L+++
Sbjct: 371 IAADDKYIVTGSGDKKATLYEV 436
>33180
          Length = 460

 Score = 35.4 bits (80), Expect = 0.029,   Method: Compositional matrix adjust.
 Identities = 29/106 (27%), Positives = 53/106 (50%), Gaps = 7/106 (6%)
 Frame = -2

Query: 225 HESDINAICFFPNGNAFATGSDDATCRLFDLRADQE-LMTYSHDNIICGITSVSFSK-SG 282
           H   I ++ F  +      G++D    ++D  ++Q  L   +HD+    + +V+F+  S 
Sbjct: 456 HSFCIFSLMFSSDNTEIVGGANDGCLYVYDRESNQRTLKIDAHDD---DVNAVAFADDSS 286

Query: 283 RLLLAGYDDFNCNVWD--ALKADRA---GVLAGHDNRVSCLGVTDD 323
           ++L +G DD  C VWD   L+ D     G++AGH + V+ +    D
Sbjct: 285 QILYSGGDDGLCKVWDRRTLREDNPLPVGIMAGHSDGVTYIDTKGD 148
>26939
          Length = 388

 Score = 35.4 bits (80), Expect = 0.030,   Method: Compositional matrix adjust.
 Identities = 20/62 (32%), Positives = 33/62 (53%), Gaps = 1/62 (1%)
 Frame = +2

Query: 238 GNAFATGSDDATCRLFDLRADQELMT-YSHDNIICGITSVSFSKSGRLLLAGYDDFNCNV 296
           G    + SDD T R++DLR  + + T Y+H +     TS+ F K+   +++G  D    V
Sbjct: 2   GKYLVSASDDKTIRVWDLRNKRCMKTLYAHQHF---CTSIDFHKAHPYVISGSVDQTVKV 172

Query: 297 WD 298
           W+
Sbjct: 173 WE 178

 Score = 30.8 bits (68), Expect = 0.84,   Method: Compositional matrix adjust.
 Identities = 20/83 (24%), Positives = 31/83 (37%)
 Frame = +2

Query: 157 IVTSSGDTTCALWDIEXXXXXXXXXXXXXDVMSLSLAPDTRLFVSGACDASAKLWDVREG 216
           +V++S D T  +WD+                 S+         +SG+ D + K+W+ R  
Sbjct: 11  LVSASDDKTIRVWDLRNKRCMKTLYAHQHFCTSIDFHKAHPYVISGSVDQTVKVWECR-- 184

Query: 217 MCRQTFTGHESDINAICFFPNGN 239
                    E   N IC F N N
Sbjct: 185 --------*EHSANNICLFLNLN 229
>18320
          Length = 450

 Score = 35.0 bits (79), Expect = 0.041,   Method: Compositional matrix adjust.
 Identities = 24/83 (28%), Positives = 39/83 (46%), Gaps = 9/83 (10%)
 Frame = -2

Query: 267 DNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDG-- 324
           D +   +  V   ++G+LL AG  D    + D  K D A   +  D ++ C+     G  
Sbjct: 293 DILFAAVDVVHLMQNGQLLAAGSRDRYLTLLDLTKYDPARPKSKKDMQLHCIDKAHSGWI 114

Query: 325 --MA-----VATGSWDSFLKIWN 340
             MA     + TGSWD+ +K+W+
Sbjct: 113 WCMASLNQHLYTGSWDTKIKVWD 45
>07665
          Length = 435

 Score = 34.7 bits (78), Expect = 0.063,   Method: Compositional matrix adjust.
 Identities = 30/95 (31%), Positives = 42/95 (44%), Gaps = 8/95 (8%)
 Frame = -2

Query: 211 WDVREGMCRQTFTGHESDINAICFFPNGNAF--ATGSD----DATCR--LFDLRADQELM 262
           WD+ +G    T   H   INA+CF PN      A G      D  C+  + +LR +    
Sbjct: 392 WDLNDGKNLYTLE-HNDIINALCFSPNRYWLCVAYGPSIKIWDLACKKTVEELRPEVVSP 216

Query: 263 TYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVW 297
           T   +   C   S+++S  G+ L AGY D    VW
Sbjct: 215 TSKAEQPQC--LSLAWSTDGQTLFAGYSDNTIRVW 117
>14500
          Length = 1238

 Score = 33.9 bits (76), Expect = 0.090,   Method: Compositional matrix adjust.
 Identities = 24/107 (22%), Positives = 44/107 (41%), Gaps = 2/107 (1%)
 Frame = +3

Query: 236 PNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLA--GYDDFN 293
           P+  A   G+ D     ++      L +    + +C +    +SK  R L++  G+    
Sbjct: 240 PSLLASGGGTADRHIHFWNCNTGTNLSSVDTKSQVCALL---WSKEHRELISSHGFAQNQ 410

Query: 294 CNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
             +W      R   L GH  RV  + ++ DG  V + + D  L++W 
Sbjct: 411 LIIWKYPAMSRVAELTGHTARVLHMAMSPDGETVVSAAADETLRLWK 551

 Score = 33.5 bits (75), Expect = 0.12,   Method: Compositional matrix adjust.
 Identities = 16/57 (28%), Positives = 25/57 (43%)
 Frame = +2

Query: 41 GRIQMRTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRS 97
          GR+      TL GH  ++  + W  D + L S + D  L +W +  T      PL +
Sbjct: 17 GRVADHHVGTLSGHSQEVCGLRWSPDGKYLASGANDNLLCVWPAQVTGGNSTQPLHT 187

 Score = 30.4 bits (67), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 15/44 (34%), Positives = 22/44 (50%)
 Frame = +3

Query: 51  LRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIP 94
           L GH A++  M    D   +VSA+ D  L +W  +T +K    P
Sbjct: 453 LTGHTARVLHMAMSPDGETVVSAAADETLRLWKCFTVDKEKKRP 584

 Score = 28.1 bits (61), Expect = 5.1,   Method: Compositional matrix adjust.
 Identities = 16/72 (22%), Positives = 33/72 (45%), Gaps = 2/72 (2%)
 Frame = +3

Query: 56  AKIYAMHWGTDSRLLVSAS--QDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVA 113
           +++ A+ W  + R L+S+      +LIIW     ++V  +   ++ V+  A +P G  V 
Sbjct: 336 SQVCALLWSKEHRELISSHGFAQNQLIIWKYPAMSRVAELTGHTARVLHMAMSPDGETVV 515

Query: 114 CGGLDNICSIYN 125
               D    ++ 
Sbjct: 516 SAAADETLRLWK 551
>01598
          Length = 1545

 Score = 33.9 bits (76), Expect = 0.10,   Method: Compositional matrix adjust.
 Identities = 28/125 (22%), Positives = 56/125 (44%), Gaps = 13/125 (10%)
 Frame = +1

Query: 104  AYAPSGNYVACGGLDNICSIYNLKT----REGNVRVS------RELAGHTGYLSCCRFLD 153
            A +P  +++A  G D +  + +L +    REG+   S      REL+GH+  ++   +  
Sbjct: 1153 AGSPCCHWLAAAGNDQVIHVVDLASVFAEREGDKETSLILTSLRELSGHSQRVTDMSWSP 1332

Query: 154  --DNQIVTSSGDTTCALWDIEXXXXXXXXXXXXXDVMSLSLAP-DTRLFVSGACDASAKL 210
              D ++V+   D    +WD++              +++   +  D  L ++G  DAS  +
Sbjct: 1333 HHDARLVSVGYDAEAFVWDVQKGTALAQFKGHMGRLLTCQFSGLDPDLVMTGGSDASVHV 1512

Query: 211  WDVRE 215
            W V +
Sbjct: 1513 WRVSQ 1527

 Score = 32.7 bits (73), Expect = 0.21,   Method: Compositional matrix adjust.
 Identities = 45/204 (22%), Positives = 70/204 (34%), Gaps = 8/204 (3%)
 Frame = +1

Query: 60  AMHW-GTDSRLLVSASQDGKLIIWD-SYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGL 117
           A+HW  ++   LVS+S  G L++W   YT  + +          T  Y P    V     
Sbjct: 241 AIHWLKSNPEQLVSSSSGGDLLLWSLRYTKGQAYQT------FQTSDYRPHMRPVF---- 390

Query: 118 DNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTTCALWDIEXXXXX 177
            NIC                  A      + C F  D Q+V         LWD+E     
Sbjct: 391 -NIC------------------ASGPDSKTLCTFAQDRQVV---------LWDLETMEAV 486

Query: 178 XXXXXXXXDVMSLSLAP-DTRLFVSGACDASAKLWDVREGMCRQTFT----GHESDINAI 232
                    V  +  +P D      G  D+  + W++         T    G +S + A+
Sbjct: 487 ASMATLGGHVYCVRTSPIDPGRVAVGVGDSMIRTWNMSNKTNPYDVTTLWQGIKSKVTAV 666

Query: 233 CFFPNGNAF-ATGSDDATCRLFDL 255
            + P    +   G+DD    +FD+
Sbjct: 667 AWHPTKEGWLGFGTDDGRIGVFDV 738

 Score = 31.2 bits (69), Expect = 0.59,   Method: Compositional matrix adjust.
 Identities = 24/68 (35%), Positives = 33/68 (48%), Gaps = 2/68 (2%)
 Frame = +1

Query: 188  MSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFP--NGNAFATGS 245
            MS S   D RL VS   DA A +WDV++G     F GH   +   C F   + +   TG 
Sbjct: 1318 MSWSPHHDARL-VSVGYDAEAFVWDVQKGTALAQFKGHMGRL-LTCQFSGLDPDLVMTGG 1491

Query: 246  DDATCRLF 253
             DA+  ++
Sbjct: 1492 SDASVHVW 1515
>15118
          Length = 1074

 Score = 33.1 bits (74), Expect = 0.15,   Method: Compositional matrix adjust.
 Identities = 38/180 (21%), Positives = 68/180 (37%), Gaps = 3/180 (1%)
 Frame = +3

Query: 109 GNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTTCAL 168
           GNYVA G       IYNL++ +        +A  +G         +  ++T+ GD     
Sbjct: 93  GNYVAVGYSSGHLDIYNLQSGKHRGSFGDTVAHVSGVRGVAFDAFNCLLITAGGDCDIKF 272

Query: 169 WDI---EXXXXXXXXXXXXXDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGH 225
           W     +              +  + L  D+ +      D +  + DV      + F+GH
Sbjct: 273 WRFGSRDRARVLLKELKMSEGISRILLHRDSNMLAVVLEDFTVSVIDVDTLRVVRVFSGH 452

Query: 226 ESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLL 285
            + I  + F  +G    T S D T R + L   + +  ++   +   +TS++ S S   L
Sbjct: 453 SNSITDLSFSGDGRWLITASMDCTVRTWSLVHGRLIDCFA---VEAAVTSLTMSPSQDFL 623

 Score = 33.1 bits (74), Expect = 0.18,   Method: Compositional matrix adjust.
 Identities = 27/135 (20%), Positives = 55/135 (40%), Gaps = 4/135 (2%)
 Frame = +3

Query: 210 LWDVREGMCRQTF---TGHESDINAICFFPNGNAFATGSDDATCRLFDLRA-DQELMTYS 265
           +++++ G  R +F     H S +  + F        T   D   + +   + D+  +   
Sbjct: 135 IYNLQSGKHRGSFGDTVAHVSGVRGVAFDAFNCLLITAGGDCDIKFWRFGSRDRARVLLK 314

Query: 266 HDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGM 325
              +  GI+ +   +   +L    +DF  +V D        V +GH N ++ L  + DG 
Sbjct: 315 ELKMSEGISRILLHRDSNMLAVVLEDFTVSVIDVDTLRVVRVFSGHSNSITDLSFSGDGR 494

Query: 326 AVATGSWDSFLKIWN 340
            + T S D  ++ W+
Sbjct: 495 WLITASMDCTVRTWS 539
>21921
          Length = 1341

 Score = 32.3 bits (72), Expect = 0.27,   Method: Compositional matrix adjust.
 Identities = 12/35 (34%), Positives = 19/35 (54%)
 Frame = -1

Query: 221 TFTGHESDINAICFFPNGNAFATGSDDATCRLFDL 255
            + GH   + +IC  P G    +GSDD T R +++
Sbjct: 498 VYKGHTGIVRSICPDPTGQWLVSGSDDGTIRFWEV 394
>04358
          Length = 2430

 Score = 32.0 bits (71), Expect = 0.34,   Method: Compositional matrix adjust.
 Identities = 60/275 (21%), Positives = 86/275 (31%), Gaps = 73/275 (26%)
 Frame = +1

Query: 139  LAGHTGYLSCCRFL--DDNQIVTSSGDTTCALWDIEXXXXXXXXXXXXXD-----VMSLS 191
            L GH   +S  RFL  D   I+T+S D T  +WD                     V+S  
Sbjct: 1408 LTGHDDVISSIRFLHTDPGLIMTASHDHTVRIWDPRASVSKEVQRFSGEQNTKCSVLSCD 1587

Query: 192  LAPDTRLFVSGAC----DASAKLWDVREGMCRQTFT-GHESDINAICFFPNGN-AFATGS 245
            +    R+  +G      DA    WD R+      +   H  DI  + F P       TGS
Sbjct: 1588 VNISDRVLCAGTEMSNDDAYLLFWDRRKDKLLGCYEDSHHDDITQVHFGPTSEKTLLTGS 1767

Query: 246  DDATCRLFDLRADQE----LMTYSHDNII-----CGITSVSF------------------ 278
             D    +FD+    E    + TY+ +  +     CG  S                     
Sbjct: 1768 TDGLVNVFDVMQTTEDDALMSTYNTEATVERAGWCGPQSQQVYAITHMLSWHVWDTEKDE 1947

Query: 279  -----------------------------SKSGRLLLAGYDDFNCNVWDALKADRAGVL- 308
                                         S S   L+AG    + +V D    +   V+ 
Sbjct: 1948 DVQQLTDLEQKLQGQCQADYLVDCIPANQSTSPPCLVAGTHTGDLHVLDLSDLEEVKVVR 2127

Query: 309  ---AGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
                GH + V CL        + TG  DS L +W+
Sbjct: 2128 SLSGGHTDTVRCLHWDKQTQTLVTGGEDSMLCLWS 2232

 Score = 28.9 bits (63), Expect = 3.6,   Method: Compositional matrix adjust.
 Identities = 12/42 (28%), Positives = 23/42 (54%), Gaps = 1/42 (2%)
 Frame = +1

Query: 44   QMRTRRTLRG-HLAKIYAMHWGTDSRLLVSASQDGKLIIWDS 84
            +++  R+L G H   +  +HW   ++ LV+  +D  L +W S
Sbjct: 2110 EVKVVRSLSGGHTDTVRCLHWDKQTQTLVTGGEDSMLCLWSS 2235
>15337
          Length = 860

 Score = 32.0 bits (71), Expect = 0.36,   Method: Compositional matrix adjust.
 Identities = 18/85 (21%), Positives = 39/85 (45%)
 Frame = -1

Query: 67  SRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNL 126
           SR L    QDG L +++  +   +  +      ++   ++P G Y+  GG D++ ++++ 
Sbjct: 293 SRYLAVVGQDGHLRVFNYNSMELIGTMKSYFGGLLCVCWSPDGKYIVTGGEDDLVTVWSF 114

Query: 127 KTREGNVRVSRELAGHTGYLSCCRF 151
             +    RV     GH  +++   F
Sbjct: 113 HEK----RVVCRGHGHKSWVNVVAF 51
>20662
          Length = 1220

 Score = 31.6 bits (70), Expect = 0.44,   Method: Compositional matrix adjust.
 Identities = 26/98 (26%), Positives = 42/98 (42%), Gaps = 5/98 (5%)
 Frame = +2

Query: 195 DTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAIC--FFPNG-NAFATGSDDATCR 251
           +  LF+S + D    LWDVRE           S     C  + PN  N +A G +     
Sbjct: 545 EPALFLSCSQDGKIVLWDVRESKPATCLPKCSSGFKPTCVQWQPNARNMYAVGDEGGHVS 724

Query: 252 LFDLR--ADQELMTYSHDNIICGITSVSFSKSGRLLLA 287
           + DLR   ++ +   SH+ +   +T ++F      +LA
Sbjct: 725 VQDLRMVVEKNVSYQSHNRV---VTRLAFCPQRPSMLA 829

 Score = 30.0 bits (66), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 21/66 (31%), Positives = 34/66 (51%), Gaps = 3/66 (4%)
 Frame = +2

Query: 65  TDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSS-WVMTCA-YAPSG-NYVACGGLDNIC 121
           T+  L +S SQDGK+++WD   +     +P  SS +  TC  + P+  N  A G      
Sbjct: 542 TEPALFLSCSQDGKIVLWDVRESKPATCLPKCSSGFKPTCVQWQPNARNMYAVGDEGGHV 721

Query: 122 SIYNLK 127
           S+ +L+
Sbjct: 722 SVQDLR 739
>10264
          Length = 416

 Score = 31.2 bits (69), Expect = 0.69,   Method: Compositional matrix adjust.
 Identities = 24/68 (35%), Positives = 33/68 (48%), Gaps = 2/68 (2%)
 Frame = -1

Query: 188 MSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFP--NGNAFATGS 245
           MS S   D RL VS   DA A +WDV++G     F GH   +   C F   + +   TG 
Sbjct: 227 MSWSPHHDARL-VSVGYDAEAFVWDVQKGTALAQFKGHMGRL-LTCQFSGLDPDLVMTGG 54

Query: 246 DDATCRLF 253
            DA+  ++
Sbjct: 53  SDASVHVW 30

 Score = 30.4 bits (67), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 27/132 (20%), Positives = 56/132 (42%), Gaps = 18/132 (13%)
 Frame = -1

Query: 102 TCAYAPSGNYVACGGLDNICSIYNLKT---------REGNVRVS------RELAGHTGYL 146
           + A +P  +++A  G D +  + +L +         REG+          REL+GH+  +
Sbjct: 413 SPAGSPRCHWLAAAGNDQVIHVVDLASVFGEMGATEREGDKETLLILTSLRELSGHSQRV 234

Query: 147 SCCRF--LDDNQIVTSSGDTTCALWDIEXXXXXXXXXXXXXDVMSLSLAP-DTRLFVSGA 203
           +   +    D ++V+   D    +WD++              +++   +  D  L ++G 
Sbjct: 233 TDMSWSPHHDARLVSVGYDAEAFVWDVQKGTALAQFKGHMGRLLTCQFSGLDPDLVMTGG 54

Query: 204 CDASAKLWDVRE 215
            DAS  +W V +
Sbjct: 53  SDASVHVWRVSQ 18
>31054
          Length = 392

 Score = 30.8 bits (68), Expect = 0.77,   Method: Compositional matrix adjust.
 Identities = 18/58 (31%), Positives = 28/58 (48%)
 Frame = -2

Query: 199 FVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLR 256
           F  G+ D   K W   +G   Q  +GH + IN +    +G    +G+D+ T  L+D R
Sbjct: 367 FAXGSPDX-VKQWKFPDGNFIQNLSGHNAIINTLAVNSDG-VLVSGADNGTMHLWDWR 200
>15972
          Length = 1069

 Score = 30.0 bits (66), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 16/56 (28%), Positives = 26/56 (46%), Gaps = 5/56 (8%)
 Frame = +3

Query: 204 CDASAKLWDVREGMC-----RQTFTGHESDINAICFFPNGNAFATGSDDATCRLFD 254
           C A  ++     G C      +TF+GH+  +  +   P+G    T S D T RL++
Sbjct: 156 CSAPVRMGPCVCGECPPG*PERTFSGHKGPVRHLAVHPSGKLTLTVSQDRTLRLWN 323
>27270
          Length = 1078

 Score = 30.0 bits (66), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 16/42 (38%), Positives = 22/42 (52%)
 Frame = +2

Query: 52  RGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAI 93
           +GH   +  M W  D R L S+S DG +I W+    N +H I
Sbjct: 263 KGHSKAVTDMCWRADGRTLYSSSLDGHVIGWN---VNTLHMI 379

 Score = 28.9 bits (63), Expect = 3.1,   Method: Compositional matrix adjust.
 Identities = 31/152 (20%), Positives = 59/152 (38%), Gaps = 6/152 (3%)
 Frame = +2

Query: 112 VACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLS-CCRFLDDNQIVTSSGDTTCALWD 170
           VA G  D    +Y+++T      +++   GH+  ++  C   D   + +SS D     W+
Sbjct: 188 VAVGSADGSVGLYSVETHTYTHMLNK---GHSKAVTDMCWRADGRTLYSSSLDGHVIGWN 358

Query: 171 IEXXXXX---XXXXXXXXDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHES 227
           +                  V  + L   +RL  +   D + K+WD+      Q F+GH +
Sbjct: 359 VNTLHMIEKWKATSGRHHGVHCVCLCSSSRLLTA---DHTIKMWDLTTKNVLQEFSGHST 529

Query: 228 DINAI--CFFPNGNAFATGSDDATCRLFDLRA 257
           ++  +     P+      G  +  C +F   A
Sbjct: 530 EVIKLLPVLKPSSEQNDIGDSNLACYVFSAAA 625
>27525
          Length = 828

 Score = 30.0 bits (66), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 13/40 (32%), Positives = 21/40 (52%)
 Frame = +2

Query: 219 RQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRAD 258
           R +F   ++ INAI F P+G+  A G  D    ++ +  D
Sbjct: 47  RNSFQVGQAQINAISFSPDGSQLAVGCHDGFVHVYVVHED 166
>22113
          Length = 614

 Score = 29.6 bits (65), Expect = 1.9,   Method: Compositional matrix adjust.
 Identities = 23/82 (28%), Positives = 41/82 (50%), Gaps = 1/82 (1%)
 Frame = +3

Query: 91  HAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTREG-NVRVSRELAGHTGYLSCC 149
           + + L  S V++  +A  G +    G DN+ + +  +T  G ++  S+E +     LSC 
Sbjct: 84  YQLHLHESCVLSLRFATCGKWFVSTGKDNLLNAW--RTPYGASIFQSKETSS---VLSCD 248

Query: 150 RFLDDNQIVTSSGDTTCALWDI 171
              DD  IVT SGD    ++++
Sbjct: 249 ISTDDKYIVTGSGDKKATVYEV 314
>31384
          Length = 474

 Score = 28.9 bits (63), Expect = 2.8,   Method: Compositional matrix adjust.
 Identities = 17/81 (20%), Positives = 34/81 (41%), Gaps = 6/81 (7%)
 Frame = -1

Query: 146 LSCCRF----LDDNQIVTSSGDTTCALWDIEXX--XXXXXXXXXXXDVMSLSLAPDTRLF 199
           +SC +F    L    +++ S D   + W+++                V+ +  + D    
Sbjct: 267 VSCLKFSPGALPSTFLISGSWDNKVSCWEVQQSGQTIPKAQQTHTGPVLDVDWSDDGTKV 88

Query: 200 VSGACDASAKLWDVREGMCRQ 220
            + +CD +AK+WD+    C Q
Sbjct: 87  FTASCDKTAKVWDLNSNQCMQ 25
>11915
          Length = 737

 Score = 28.9 bits (63), Expect = 2.8,   Method: Compositional matrix adjust.
 Identities = 19/67 (28%), Positives = 32/67 (47%), Gaps = 4/67 (5%)
 Frame = +1

Query: 54  HLAKIYAMHWGTDSRL-LVSASQDGKLIIW---DSYTTNKVHAIPLRSSWVMTCAYAPSG 109
           H A ++ +H+  D+ L L+SAS DG + +W   D    N    +   +    +C ++   
Sbjct: 529 HKATVHDLHFAADNSLCLMSASHDGTVKLWEFDDQGDCNMYLTLRTNAKHAFSCRWSHDR 708

Query: 110 NYVACGG 116
            YVA  G
Sbjct: 709 RYVATAG 729
>12140
          Length = 727

 Score = 28.9 bits (63), Expect = 3.3,   Method: Compositional matrix adjust.
 Identities = 17/63 (26%), Positives = 31/63 (49%), Gaps = 3/63 (4%)
 Frame = +2

Query: 222 FTGHESDINAICFFPN--GNAFATGSDDATCRLFDLRADQELMTYSHDNI-ICGITSVSF 278
           ++ H+S +N++CF P+  G   A GS D +  +     D    +   +N    G  +VS+
Sbjct: 26  YSNHDSSVNSVCFAPHELGLILACGSSDGSLSIISTTGDGNWDSKKINNAHTIGCNAVSW 205

Query: 279 SKS 281
           + S
Sbjct: 206 APS 214

 Score = 27.7 bits (60), Expect = 7.6,   Method: Compositional matrix adjust.
 Identities = 24/89 (26%), Positives = 40/89 (44%), Gaps = 13/89 (14%)
 Frame = +2

Query: 49  RTLRGHLAKIYAMHW----GTDSRLLVSASQDGKLIIW------DSYTT---NKVHAIPL 95
           + L GH   +  + W    G    ++ S SQD ++IIW      + +T+   NK   +  
Sbjct: 338 QKLEGHSDWVRDVAWAPSIGLPRNVIASCSQDCRVIIWTNDGSSNQWTSRILNKFSDVVW 517

Query: 96  RSSWVMTCAYAPSGNYVACGGLDNICSIY 124
             SW +T      GN +A  G DN  +++
Sbjct: 518 HVSWSVT------GNILAVSGGDNKVTLW 586
>04524
          Length = 1340

 Score = 28.1 bits (61), Expect = 5.3,   Method: Compositional matrix adjust.
 Identities = 11/33 (33%), Positives = 23/33 (69%), Gaps = 1/33 (3%)
 Frame = -1

Query: 141 GHTGYLSCCRFLDDNQIVTS-SGDTTCALWDIE 172
           GHT +++C  ++++ +++ S SGD T   W++E
Sbjct: 905 GHTQFVNCLVYVEEFRVLISGSGDCTVRAWNME 807
>07781
          Length = 1269

 Score = 28.1 bits (61), Expect = 5.6,   Method: Compositional matrix adjust.
 Identities = 26/93 (27%), Positives = 42/93 (45%), Gaps = 4/93 (4%)
 Frame = -2

Query: 210 LWDVREGMCRQTFTGHESDINA-ICFFPNGNA--FATGSDDATCRLFDLRADQELMTYSH 266
           +++V     R+T      D  A IC F   N     +GSDD   +++DLR     +  ++
Sbjct: 848 VFEVESTTVRETSQWRAHDFEAWICAFDQWNTELIYSGSDDCKLKVWDLRVGTTPV-LTN 672

Query: 267 DNIICGITSV-SFSKSGRLLLAGYDDFNCNVWD 298
                G+TS+ S  +   LL  G  D N  ++D
Sbjct: 671 SRFTMGVTSIQSCPQREHLLAVGSYDENLRLFD 573
>38177
          Length = 430

 Score = 27.3 bits (59), Expect = 8.0,   Method: Compositional matrix adjust.
 Identities = 13/65 (20%), Positives = 28/65 (43%)
 Frame = +3

Query: 276 VSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSF 335
           ++++  GR L+ G       +W+ L  +   +L  HD  V  +  ++    + T     +
Sbjct: 6   LAWTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDVSVRAMRWSNHDQWMVTADHSGY 185

Query: 336 LKIWN 340
           +K W 
Sbjct: 186 IKYWQ 200
>27681
          Length = 465

 Score = 27.3 bits (59), Expect = 8.2,   Method: Compositional matrix adjust.
 Identities = 24/109 (22%), Positives = 47/109 (43%), Gaps = 1/109 (0%)
 Frame = +2

Query: 232 ICFF-PNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYD 290
           IC + P  +  A+GS D+T R++++                  TS + + + +L+L    
Sbjct: 8   ICAWNPTNDLLASGSGDSTARIWNM------------------TSETPNNANQLVLR--- 124

Query: 291 DFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIW 339
             +C         + G     +  V+ L    +G  +ATGS+D + ++W
Sbjct: 125 --HC-------IQKGGTEVPSNKDVTSLDWNSEGTLLATGSYDGYARLW 244
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31560168|ref|NP_080763.2| ATPase family, AAA domain
containing 1 [Mus musculus]
         (361 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

00810                                                                 306   6e-84
07243                                                                 146   2e-35
01642                                                                 141   5e-34
03022                                                                 140   1e-33
20270                                                                 120   1e-33
23766                                                                 117   8e-30
19129                                                                 123   1e-28
02582                                                                 111   4e-25
07247                                                                 105   1e-24
25671                                                                  86   3e-17
12235                                                                  79   2e-15
38672                                                                  66   2e-14
17843                                                                  55   3e-08
06766                                                                  52   3e-07
26408                                                                  52   4e-07
02194                                                                  49   3e-06
19561                                                                  37   0.012
01279                                                                  33   0.12 
04762                                                                  33   0.20 
00347                                                                  32   0.34 
00531                                                                  32   0.45 
14764                                                                  28   6.6  
09968                                                                  27   9.2  
>00810
          Length = 1431

 Score =  306 bits (785), Expect = 6e-84,   Method: Compositional matrix adjust.
 Identities = 158/256 (61%), Positives = 198/256 (77%), Gaps = 4/256 (1%)
 Frame = -3

Query: 96   LDDVITDLKDTVILPIKKKHLFENSRLLQPPKGVLLYGPPGCGKTLIAKATAKEAGCRFI 155
            L+DVI D+K+TVILP K+  LF +S LLQPPKGVLL+GPPGCGKT+IAKATAK AG RFI
Sbjct: 1429 LEDVIQDVKETVILPFKRADLFRHSSLLQPPKGVLLHGPPGCGKTMIAKATAKAAGARFI 1250

Query: 156  NLQPSTLTDKWYGESQKLAAAVFSLAIKLQPSIIFIDEIDSFLRNRSSSDHEATAMMKAQ 215
            NLQ S+L DKWYGESQK A AVFSLAIKLQP+IIFIDEIDSFLR+R+S+DHEATAM+K Q
Sbjct: 1249 NLQVSSLVDKWYGESQKRAEAVFSLAIKLQPTIIFIDEIDSFLRSRTSTDHEATAMIKTQ 1070

Query: 216  FMSLWDGLDTDHSCQVIVMGATNRPQDLDSAIMRRMPTRFHINQPALKQREAILKLILKN 275
            FMS WDGL TD  C+V+VMGATNRPQD+D+AI+RRMP+ FHI  P   QR +I  LIL  
Sbjct: 1069 FMSFWDGLMTDPDCRVMVMGATNRPQDVDAAILRRMPSMFHIGLPGPAQRRSIFNLILSK 890

Query: 276  ENVDRHVDLLEVAQETDGFSGSDLKEMCRDAALLCVREYVNST----SEESHDEDEIRPV 331
            E +D  ++  E+A+ TDGFSGSD++E+CR AA+  V E++            D+  +R +
Sbjct: 889  ERID-ALNYDELAEMTDGFSGSDIREVCRAAAVATVHEFIQEEVVRGDNNPEDDRGLRNL 713

Query: 332  QQQDLHRAIEKMKKSK 347
              +DL  +I K++++K
Sbjct: 712  TMRDLQLSITKVQQTK 665
>07243
          Length = 1112

 Score =  146 bits (368), Expect = 2e-35,   Method: Compositional matrix adjust.
 Identities = 99/281 (35%), Positives = 148/281 (52%), Gaps = 14/281 (4%)
 Frame = +1

Query: 81  VDPL--NMH------VTWSDIAGLDDVITDLKDTVILPIKKKHLFENSRLLQPPKGVLLY 132
           VDPL  NM       VT+S I GL + I +L++ + LP+    LF    +  PPKG LLY
Sbjct: 151 VDPLVYNMSHEDPGDVTYSAIGGLTEQIRELREVIELPLLNPELFLRVGI-TPPKGCLLY 327

Query: 133 GPPGCGKTLIAKATAKEAGCRFINLQPSTLTDKWYGESQKLAAAVFSLAIKLQPSIIFID 192
           GPPG GKTL+A+A A +    F+ +  S + DK+ GES +L   +F+ A   QP IIF+D
Sbjct: 328 GPPGTGKTLLARAVASQLDANFLKVVSSAIVDKYIGESARLIREMFNYARDHQPCIIFMD 507

Query: 193 EIDSFLRNRSSSDHEATAMMKAQFMSLWDGLDT-DHSCQVIVMGATNRPQDLDSAIMR-- 249
           EID+    R S    A   ++   M L + +D  D   QV ++ ATNRP  LD A++R  
Sbjct: 508 EIDAIGGRRFSEGTSADREIQRTLMELLNQMDGFDSLGQVKMIMATNRPDTLDPALLRPG 687

Query: 250 RMPTRFHINQPALKQREAILK---LILKNENVDRHVDLLEVAQETDGFSGSDLKEMCRDA 306
           R+  +  I  P  + R  ILK   LI+        +D   + + +D F+G+DL+ +C +A
Sbjct: 688 RLDRKIEIPLPNEQARLEILKIHALIIAKHG---EIDYEAIVKLSDNFNGADLRNVCTEA 858

Query: 307 ALLCVREYVNSTSEESHDEDEIRPVQQQDLHRAIEKMKKSK 347
            L  +R      +E  +       V Q+D  +A+ K+  +K
Sbjct: 859 GLFAIR------AEREY-------VIQEDFMKAVRKVSDNK 942
>01642
          Length = 1406

 Score =  141 bits (355), Expect = 5e-34,   Method: Compositional matrix adjust.
 Identities = 79/227 (34%), Positives = 122/227 (53%), Gaps = 3/227 (1%)
 Frame = -1

Query: 90  WSDIAGLDDVITDLKDTVILPIKKKHLFENSRLLQPPKGVLLYGPPGCGKTLIAKATAKE 149
           +SDI G+D    ++++ V LP+    L++   +  PP+GVL+YGPPGCGKT++AKA A  
Sbjct: 998 YSDIGGMDIQKQEVREAVELPLTHFELYKQIGI-DPPRGVLMYGPPGCGKTMLAKAVAHH 822

Query: 150 AGCRFINLQPSTLTDKWYGESQKLAAAVFSLAIKLQPSIIFIDEIDSFLRNRSSSDHEAT 209
               FI +  S    K+ GE  ++   VF LA +  P+IIFIDEID+    R  +   A 
Sbjct: 821 TTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRFDAQTGAD 642

Query: 210 AMMKAQFMSLWDGLDT-DHSCQVIVMGATNRPQDLDSAIMR--RMPTRFHINQPALKQRE 266
             ++   + L + +D  D +  V V+ ATNR   LD A++R  R+  +     P  +Q+ 
Sbjct: 641 REVQRILLELLNQMDGFDQTVNVKVIMATNRADTLDPALLRPGRLDRKIEFPLPDRRQKR 462

Query: 267 AILKLILKNENVDRHVDLLEVAQETDGFSGSDLKEMCRDAALLCVRE 313
            I   I    N+   VDL +     D  SG+D+  +C++A +  VRE
Sbjct: 461 LIFSTITGKMNISEEVDLEDYVARPDKISGADINAICQEAGMQAVRE 321
>03022
          Length = 2255

 Score =  140 bits (352), Expect = 1e-33,   Method: Compositional matrix adjust.
 Identities = 96/270 (35%), Positives = 144/270 (53%), Gaps = 11/270 (4%)
 Frame = +2

Query: 88   VTWSDIAGLDDVITDLKDTVILPIKKKHLFENSRLLQPP--KGVLLYGPPGCGKTLIAKA 145
             TW D+  L +V   LKD+++  I   H  E S     P   G++L GPPGCGKTL+AKA
Sbjct: 1418 TTWEDVGALSNVRAQLKDSILCRI---HDPEVSSAFGLPTNSGIILVGPPGCGKTLVAKA 1588

Query: 146  TAKEAGCRFINLQPSTLTDKWYGESQKLAAAVFSLAIKLQPSIIFIDEIDSFLRNRSSSD 205
             A EAG  FI ++   L DK+ GES++     F  A    P +IF DE+D+   NR ++D
Sbjct: 1589 MANEAGLNFIYIKGPELLDKYVGESERNLREKFDKAQACAPCLIFFDEMDTLCSNRQNND 1768

Query: 206  HEATAM-MKAQFMSLWDGLDTDHSCQVIVMGATNRPQDLDSAIMRRMPTRF----HINQP 260
                   +  Q ++L DG       QV VMGATN  +++D A+ R  P RF     I  P
Sbjct: 1769 GSNVGKSVTNQLLALMDGC--GERSQVYVMGATNIIENVDPALQR--PGRFDRKIFIGLP 1936

Query: 261  ALKQREAILKLILKNENVDR--HVDLLEVAQETDGFSGSDLKEMCRDAALLCVREYVNST 318
                R  IL+ + K  +  +    D+ ++AQ+T+GFSG+DLK +  +A+ + ++E   S 
Sbjct: 1937 DTDGRLDILRALTKGGSQRKLESCDMQQLAQDTEGFSGADLKHLVNEASTIALKE---SM 2107

Query: 319  SEESHDEDEIRP--VQQQDLHRAIEKMKKS 346
            ++++  ED  R   V      RA++ +K S
Sbjct: 2108 ADQAWREDSHREYVVTGDQFTRALQLVKPS 2197
>20270
          Length = 542

 Score =  120 bits (300), Expect(2) = 1e-33,   Method: Compositional matrix adjust.
 Identities = 61/129 (47%), Positives = 85/129 (65%), Gaps = 1/129 (0%)
 Frame = -3

Query: 124 QPPKGVLLYGPPGCGKTLIAKATAKEAG-CRFINLQPSTLTDKWYGESQKLAAAVFSLAI 182
           +P +G+LLYGPPG GK+ +AKA A EA    F ++  S L  KW GES+KL   +F LA 
Sbjct: 387 KPWRGILLYGPPGTGKSYLAKAVATEANNSTFFSVSSSDLVSKWLGESEKLVKTLFQLAR 208

Query: 183 KLQPSIIFIDEIDSFLRNRSSSDHEATAMMKAQFMSLWDGLDTDHSCQVIVMGATNRPQD 242
           + QPSIIFIDE+D+   +RS ++ E+   +K +F+    G+  D++  V+V+GATN P  
Sbjct: 207 ENQPSIIFIDEVDALCGSRSENESESARRIKTEFLVQMQGVGNDNT-GVLVLGATNIPWT 31

Query: 243 LDSAIMRRM 251
           LDSAI RR 
Sbjct: 30  LDSAIRRRF 4

 Score = 41.2 bits (95), Expect(2) = 1e-33,   Method: Compositional matrix adjust.
 Identities = 20/47 (42%), Positives = 29/47 (61%)
 Frame = -1

Query: 75  SIAAHLVDPLNMHVTWSDIAGLDDVITDLKDTVILPIKKKHLFENSR 121
           ++ +H+V+  N  V W D+AGL+     LK+ VILP+K  HLF   R
Sbjct: 521 AVRSHVVEKPN--VRWDDVAGLNGAKDALKEAVILPVKFPHLFTGKR 387
>23766
          Length = 1463

 Score =  117 bits (294), Expect(2) = 8e-30,   Method: Compositional matrix adjust.
 Identities = 72/205 (35%), Positives = 109/205 (53%), Gaps = 8/205 (3%)
 Frame = +1

Query: 117 FENSRLL-----QPPKGVLLYGPPGCGKTLIAKATAKEAGCRFINLQPSTLTDKWYGESQ 171
            ++SR+L     Q PKGV+LYGPPG GKTL+AKA A +    F+ +  S L  K+ G+  
Sbjct: 112 IDSSRVLRRDGNQAPKGVILYGPPGTGKTLLAKAVANQTSATFLRVVGSELIQKYLGDGP 291

Query: 172 KLAAAVFSLAIKLQPSIIFIDEIDSFLRNRSSSDHEATAMMKAQFMSLWDGLDT-DHSCQ 230
           KL   +F +A +  PSI+FIDEID+    R  S+      ++   + L + LD  D    
Sbjct: 292 KLVRELFRVAEEHAPSIVFIDEIDAVGTKRYESNSGGEREIQRTMLELLNQLDGFDSRGD 471

Query: 231 VIVMGATNRPQDLDSAIMR--RMPTRFHINQPALKQREAILKLILKNENVDRHVDLLEVA 288
           V V+ ATNR + LD A++R  R+  +     P  K +  I  +      +   V++ +  
Sbjct: 472 VKVIMATNRIETLDPALIRPGRIDRKIEFPLPDEKTKRRIFTIHTSRMTLAGDVNIDDYV 651

Query: 289 QETDGFSGSDLKEMCRDAALLCVRE 313
              D  SG+D+K +C +A LL +RE
Sbjct: 652 MSKDDLSGADIKAICTEAGLLALRE 726

 Score = 30.4 bits (67), Expect(2) = 8e-30,   Method: Compositional matrix adjust.
 Identities = 12/31 (38%), Positives = 20/31 (64%)
 Frame = +2

Query: 89  TWSDIAGLDDVITDLKDTVILPIKKKHLFEN 119
           T++DI GLD  I ++K++V LP+     +E 
Sbjct: 47  TYADIGGLDTQIQEIKESVELPLTHPEYYEE 139
>19129
          Length = 1020

 Score =  123 bits (309), Expect = 1e-28,   Method: Compositional matrix adjust.
 Identities = 71/171 (41%), Positives = 98/171 (57%), Gaps = 4/171 (2%)
 Frame = +1

Query: 89  TWSDIAGLDDVITDLKDTVILPIKKKHLFENSRLLQPPKGVLLYGPPGCGKTLIAKATAK 148
           T+  + GLD  I ++K+ + LP+K   LFE   + QP KGVLLYGPPG GKTL+A+A A 
Sbjct: 481 TYEMVGGLDKQIKEIKEVIELPVKHPELFEALGIAQP-KGVLLYGPPGTGKTLLARAVAH 657

Query: 149 EAGCRFINLQPSTLTDKWYGESQKLAAAVFSLAIKLQPSIIFIDEIDSF----LRNRSSS 204
              C FI +  S L  K+ GE  ++   +F +A +  PSIIF+DEIDS     L   S  
Sbjct: 658 HTECTFIRVSGSELVQKFIGEGSRMVRELFVMAREHAPSIIFMDEIDSIGSSRLEGGSGG 837

Query: 205 DHEATAMMKAQFMSLWDGLDTDHSCQVIVMGATNRPQDLDSAIMRRMPTRF 255
           D E    M  + ++  DG +   + +VI+  ATNR   LDSA++R  P R 
Sbjct: 838 DSEVQRTM-LELLNQLDGFEPKQNIKVIM--ATNRIDILDSALLR--PGRI 975
>02582
          Length = 1101

 Score =  111 bits (278), Expect = 4e-25,   Method: Compositional matrix adjust.
 Identities = 83/273 (30%), Positives = 137/273 (50%), Gaps = 34/273 (12%)
 Frame = +3

Query: 88  VTWSDIAGLDDVITDLKDTVILPIKKKHLFENSRLLQPPKGVLLYGPPGCGKTLIAKATA 147
           V W+DI GLD V   ++  V  P+     F+ +  L   KGVLLYGPPGCGKT +A+A A
Sbjct: 132 VPWTDIGGLDLVKLQIRQAVEWPLLYPDTFQ-ALGLPLTKGVLLYGPPGCGKTTLAQAAA 308

Query: 148 KEAGCRFINLQPSTLTDKWYGESQKLAAAVFSLAIKLQPSIIFIDEIDSFLRNRSSSD-- 205
                 F++L  + L   + G+++K  +  F  A  L PSI+F+DE+D+ +  RS S   
Sbjct: 309 TACHVTFLSLSCAQLYSPYVGDAEKKISETFQKARALAPSILFLDEMDAIVGKRSDSSLG 488

Query: 206 HEATAMMKAQFMSLWDGL-----------------DTDHSCQ-------------VIVMG 235
              +  + +  ++  DG+                  +DH+ Q             V+V+ 
Sbjct: 489 SGVSERVLSALLNEMDGIGVRLDDKSDSREMEIEGSSDHTPQVRQHAVKEAHDRHVLVVA 668

Query: 236 ATNRPQDLDSAIMR--RMPTRFHINQPALKQREAILKLILKNENVDRHVDLLEVAQETDG 293
           ATNRP  LD A++R  RM    ++  P ++ R     +  +   + + VD+ ++A  T G
Sbjct: 669 ATNRPDMLDPALLRPGRMDRLIYVPPPDVQGRLQSFTIHTRKMPLGKDVDVKQLADLTAG 848

Query: 294 FSGSDLKEMCRDAALLCVREYVNSTSEESHDED 326
           ++G+D+K +C +  LL ++E   S S E  ++D
Sbjct: 849 YTGADIKTLCNEVGLLALKE---SMSAECVNQD 938
>07247
          Length = 1753

 Score =  105 bits (263), Expect(2) = 1e-24,   Method: Compositional matrix adjust.
 Identities = 64/190 (33%), Positives = 102/190 (53%), Gaps = 3/190 (1%)
 Frame = -2

Query: 135  PGCGKTLIAKATAKEAGCRFINLQPSTLTDKWYGESQKLAAAVFSLAIKLQPSIIFIDEI 194
            PG GKTL+A+A A +  C F+ +  S + DK+ GES +L   +F+ A   +P IIF+DEI
Sbjct: 1407 PGTGKTLLARAVASQLDCNFLKVVSSAIVDKYIGESARLIREMFAFARDHEPCIIFMDEI 1228

Query: 195  DSFLRNRSSSDHEATAMMKAQFMSLWDGLDT-DHSCQVIVMGATNRPQDLDSAIMR--RM 251
            D+    R S    A   ++   M L + +D  D   QV ++ ATNRP  LD A++R  R+
Sbjct: 1227 DAIGGRRFSEGTSADREIQRTLMELLNQMDGFDALGQVKMIMATNRPDTLDPALLRPGRL 1048

Query: 252  PTRFHINQPALKQREAILKLILKNENVDRHVDLLEVAQETDGFSGSDLKEMCRDAALLCV 311
              +  I+ P  + R  ILK+          +D   V + ++ F+G+DL+ +C +A +  +
Sbjct: 1047 DRKIEISLPNEQARLEILKIHANPIAKHGEIDWEAVVKLSEDFNGADLRNVCTEAGMFAI 868

Query: 312  REYVNSTSEE 321
            R   +   EE
Sbjct: 867  RAERDYVIEE 838

 Score = 25.0 bits (53), Expect(2) = 1e-24,   Method: Compositional matrix adjust.
 Identities = 9/12 (75%), Positives = 10/12 (83%)
 Frame = -3

Query: 124  QPPKGVLLYGPP 135
             PPKG LL+GPP
Sbjct: 1439 HPPKGCLLFGPP 1404
>25671
          Length = 441

 Score = 85.5 bits (210), Expect = 3e-17,   Method: Compositional matrix adjust.
 Identities = 48/107 (44%), Positives = 67/107 (62%), Gaps = 4/107 (3%)
 Frame = +2

Query: 138 GKTLIAKATAKEAGCRFINLQPSTLTDKWYGESQKLAAAVFSLAIKLQPSIIFIDEIDSF 197
           GKT++AKA A E G  F N+  S+L +K+ GES+KL   +F +A    PS IFIDEIDS 
Sbjct: 5   GKTMLAKAVATECGTTFFNVSTSSLANKYRGESEKLVRLLFEMAHFYAPSTIFIDEIDSI 184

Query: 198 LRNRSS-SDHEATAMMKAQFMSLWDGL---DTDHSCQVIVMGATNRP 240
              R S S+HEA+  +K++ +   DG+   + D S  V+V+ ATN P
Sbjct: 185 CSKRGSDSEHEASRRVKSELLVQMDGVGVTNDDPSKAVMVLAATNFP 325
>12235
          Length = 1749

 Score = 79.3 bits (194), Expect = 2e-15,   Method: Compositional matrix adjust.
 Identities = 62/193 (32%), Positives = 99/193 (51%), Gaps = 10/193 (5%)
 Frame = +1

Query: 149 EAGCRFINLQPSTLTDKWYGESQKLAAAVFSLAIKLQPSIIFIDEIDSFLRNRSSSDHEA 208
           EA   FI +  S   + + G        +F+ A K  P I+F+DEID+  R RS  +   
Sbjct: 1   EANVPFITVSGSEFLEMFVGVGPSRVRDMFATARKNAPCILFVDEIDAVGRKRSGRNFGG 180

Query: 209 TAMMK---AQFMSLWDGLDTDHSCQVIVMGATNRPQDLDSAIMRRMPTRF----HINQPA 261
            +  +    Q +   DG +T     V+V+ ATNR   LD+A++R  P RF     +  P 
Sbjct: 181 QSEQENTLNQLLVEMDGFNT--QTGVVVLAATNRVDILDAALLR--PGRFDRQIFVPLPD 348

Query: 262 LKQREAILKL---ILKNENVDRHVDLLEVAQETDGFSGSDLKEMCRDAALLCVREYVNST 318
           +K R +I K+    LK E V+++    ++A  T GFSG+D+  +C +AAL+  R+ +N++
Sbjct: 349 IKXRASIFKVHLDPLKTE-VNKNDLARKMAALTPGFSGADIANVCNEAALIAARD-LNTS 522

Query: 319 SEESHDEDEIRPV 331
              +H E  I  V
Sbjct: 523 IHMTHFEQAIERV 561
>38672
          Length = 730

 Score = 66.2 bits (160), Expect(2) = 2e-14,   Method: Compositional matrix adjust.
 Identities = 41/105 (39%), Positives = 58/105 (55%), Gaps = 2/105 (1%)
 Frame = -3

Query: 214 AQFMSLWDGLDTDHSCQVIVMGATNRPQDLDSAIMR--RMPTRFHINQPALKQREAILKL 271
           +Q ++L DGL       VIVM ATNRP  +D+A+ R  R      I  P    R  IL++
Sbjct: 575 SQLLTLMDGLK--QRSHVIVMAATNRPNSVDAALRRFGRFDREVDIGIPDATGRLEILRI 402

Query: 272 ILKNENVDRHVDLLEVAQETDGFSGSDLKEMCRDAALLCVREYVN 316
             KN  +   VDL +VA ET G  G+D+  +C +AAL  +RE ++
Sbjct: 401 HTKNMKLADDVDLEQVASETHGHVGADVAALCSEAALQQIREKMD 267

 Score = 30.0 bits (66), Expect(2) = 2e-14,   Method: Compositional matrix adjust.
 Identities = 16/40 (40%), Positives = 21/40 (52%)
 Frame = -1

Query: 162 LTDKWYGESQKLAAAVFSLAIKLQPSIIFIDEIDSFLRNR 201
           +  K  GES+      F  A K  P+IIFIDE+D+    R
Sbjct: 730 IMSKLAGESESNLRKAFEEAEKNAPAIIFIDELDAIAPKR 611
>17843
          Length = 772

 Score = 55.5 bits (132), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 62/245 (25%), Positives = 107/245 (43%), Gaps = 22/245 (8%)
 Frame = +1

Query: 68  KLSEYEMSIAAHLVDP-LNMHVTWSDIAGLDDVITDLKD--TVILPIKKKHLFENSRLLQ 124
           +L E  +S+A+  V P  + H  W  +   +++   L +  T  L    KH+  NS ++ 
Sbjct: 7   ELDEENVSMASQWVLPSAHFHGHWDSLVFDENIKERLLNYATTTLLFSDKHV--NSSIIS 180

Query: 125 PPKGVLLYGPPGCGKTLIAKATAKEAGCR---------FINLQPSTLTDKWYGESQKLAA 175
             + +LL+GPPG GKT + KA A +   R          + +   +L  KW+ ES KL  
Sbjct: 181 WNRVILLHGPPGTGKTTLCKALAHKLCIRLSHRFSCGQLVEINSHSLFSKWFSESGKLVT 360

Query: 176 AVFSLA--IKLQPSI---IFIDEIDSFLRNRSSS-----DHEATAMMKAQFMSLWDGLDT 225
            +F       + P +   + IDE++S    R S        +A  ++ A    + D L  
Sbjct: 361 KMFQRLHDYMVDPELLVCVLIDEVESLTAARKSCLNGNEPSDAIRVVNAVLTQI-DQLKK 537

Query: 226 DHSCQVIVMGATNRPQDLDSAIMRRMPTRFHINQPALKQREAILKLILKNENVDRHVDLL 285
             +C  +++  +N    +D A + R   + +I  P      AI K+ L   N    V ++
Sbjct: 538 FANC--LILTTSNITGAIDLAFVDRADIKQYIGPPT---PPAIYKIYLSCLNELMRVGII 702

Query: 286 EVAQE 290
             AQ+
Sbjct: 703 HPAQQ 717
>06766
          Length = 976

 Score = 52.0 bits (123), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 29/78 (37%), Positives = 43/78 (55%)
 Frame = +2

Query: 250 RMPTRFHINQPALKQREAILKLILKNENVDRHVDLLEVAQETDGFSGSDLKEMCRDAALL 309
           R+    +I  P  K REAILK  L+   + + VDL  +A+ T GFSG+DL E+C+ A  L
Sbjct: 2   RLDQLIYIPLPDDKSREAILKANLRKSPLAKEVDLTYIAKVTQGFSGADLTEICQRACKL 181

Query: 310 CVREYVNSTSEESHDEDE 327
            +R+ + +      D  E
Sbjct: 182 AIRQAIEAEIRREKDRAE 235
>26408
          Length = 463

 Score = 52.0 bits (123), Expect = 4e-07,   Method: Compositional matrix adjust.
 Identities = 25/45 (55%), Positives = 33/45 (73%)
 Frame = +1

Query: 103 LKDTVILPIKKKHLFENSRLLQPPKGVLLYGPPGCGKTLIAKATA 147
           +K+ + LP+K   LF+   + QP KGVLLYGPPG GKTL+A+A A
Sbjct: 298 IKEVIELPVKHPELFDALGIAQP-KGVLLYGPPGTGKTLLARAVA 429
>02194
          Length = 1891

 Score = 49.3 bits (116), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 43/139 (30%), Positives = 66/139 (47%), Gaps = 6/139 (4%)
 Frame = -1

Query: 127  KGVLLYGPPGCGKT--LIAKATAKEAGCRFINLQPSTLTDKWYGESQKLAAAVFSLAIKL 184
            +G LLYGPPGCGK+  ++A A A +     +NL    L+D               L +  
Sbjct: 1495 RGYLLYGPPGCGKSSYIMALAGALDYNICVLNLSEKGLSDDRLNH---------LLTVAP 1343

Query: 185  QPSIIFIDEID-SFLRNRSSSDHEAT--AMMKAQFMSLWDGLDTDHSCQV-IVMGATNRP 240
            + SII ++++D +FL    S ++ A    M +  F  L + LD   S +  IV   TN  
Sbjct: 1342 EQSIILLEDVDAAFLSRDLSKENPAMYQGMGRLTFSGLLNALDGVASAEARIVFMTTNYL 1163

Query: 241  QDLDSAIMRRMPTRFHINQ 259
              LD A++R  P R  + +
Sbjct: 1162 DRLDPALIR--PGRVDMKE 1112
>19561
          Length = 474

 Score = 37.0 bits (84), Expect = 0.012,   Method: Compositional matrix adjust.
 Identities = 25/76 (32%), Positives = 35/76 (46%), Gaps = 6/76 (7%)
 Frame = -1

Query: 127 KGVLLYGPPGCGKTLIAKATAKEAGCRFINLQPS------TLTDKWYGESQKLAAAVFSL 180
           K  LL GPPG GKT +A   AK AG   + +  S        ++K    +Q  A     +
Sbjct: 378 KVALLCGPPGLGKTTLAHIVAKHAGYNVVEMNASDDRSVEVFSNKIEAATQMRAV----M 211

Query: 181 AIKLQPSIIFIDEIDS 196
               +P+ + IDEID 
Sbjct: 210 GADPRPNCLIIDEIDG 163
>01279
          Length = 2183

 Score = 33.5 bits (75), Expect = 0.12,   Method: Compositional matrix adjust.
 Identities = 16/27 (59%), Positives = 19/27 (70%)
 Frame = -3

Query: 127  KGVLLYGPPGCGKTLIAKATAKEAGCR 153
            + VLL GPPG GKT IA A A+E G +
Sbjct: 1914 RAVLLAGPPGTGKTAIALAIAQELGNK 1834
>04762
          Length = 916

 Score = 33.1 bits (74), Expect = 0.20,   Method: Compositional matrix adjust.
 Identities = 13/41 (31%), Positives = 24/41 (58%)
 Frame = +2

Query: 198 LRNRSSSDHEATAMMKAQFMSLWDGLDTDHSCQVIVMGATN 238
           LRNR+ S   + A +K +F  L+    T H C+++++  +N
Sbjct: 758 LRNRNGSKSTSGAPLKIKFRILYHSCQTSHICRIVLILGSN 880
>00347
          Length = 592

 Score = 32.3 bits (72), Expect = 0.34,   Method: Compositional matrix adjust.
 Identities = 15/51 (29%), Positives = 27/51 (52%)
 Frame = +2

Query: 90  WSDIAGLDDVITDLKDTVILPIKKKHLFENSRLLQPPKGVLLYGPPGCGKT 140
           W D+   ++++T+ +    + I    L  NSR+ Q P+  + +G P CG T
Sbjct: 287 WFDVQEXEEILTE*RTQGAIAI----LNINSRVYQSPEAKIYFGSPYCGMT 427
>00531
          Length = 1457

 Score = 32.0 bits (71), Expect = 0.45,   Method: Compositional matrix adjust.
 Identities = 15/51 (29%), Positives = 27/51 (52%)
 Frame = -1

Query: 90  WSDIAGLDDVITDLKDTVILPIKKKHLFENSRLLQPPKGVLLYGPPGCGKT 140
           W D+   ++++T+ +    + I    L  NSR+ Q P+  + +G P CG T
Sbjct: 461 WFDVQESEEILTE*RTQGAIAI----LNINSRVYQSPEAKIYFGSPYCGMT 321
>14764
          Length = 2105

 Score = 27.7 bits (60), Expect = 6.6,   Method: Compositional matrix adjust.
 Identities = 13/34 (38%), Positives = 17/34 (50%)
 Frame = -2

Query: 293  GFSGSDLKEMCRDAALLCVREYVNSTSEESHDED 326
            G SG     +CR A   C   Y+ S  EE+H +D
Sbjct: 1366 GSSGQSAVRICRPAQXKCQPSYLLSALEEAHPQD 1265
>09968
          Length = 2913

 Score = 27.3 bits (59), Expect = 9.2,   Method: Compositional matrix adjust.
 Identities = 24/65 (36%), Positives = 30/65 (46%), Gaps = 3/65 (4%)
 Frame = -2

Query: 277  NVDRHVDLLEVAQETDG---FSGSDLKEMCRDAALLCVREYVNSTSEESHDEDEIRPVQQ 333
            N D  V   E AQE DG     G D+ EM  +A    V        EE  DED++   +Q
Sbjct: 2561 NGDESVMNEEEAQEQDGEEELEGGDI-EMTTEAPDNLVD------GEEVMDEDQLGAGEQ 2403

Query: 334  QDLHR 338
            +DLH 
Sbjct: 2402 EDLHE 2388
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|45433560|ref|NP_032475.2| kinesin family member 5C
[Mus musculus]
         (956 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

13148                                                                 308   6e-84
33215                                                                 181   2e-45
12048                                                                 166   6e-41
11818                                                                 105   5e-34
02896                                                                 125   6e-29
28434                                                                 113   3e-25
38050                                                                  55   2e-23
14618                                                                 102   1e-21
15043                                                                  95   1e-19
34477                                                                  83   7e-16
34899                                                                  78   2e-14
17748                                                                  70   5e-12
>13148
          Length = 653

 Score =  308 bits (789), Expect = 6e-84,   Method: Compositional matrix adjust.
 Identities = 144/176 (81%), Positives = 159/176 (90%)
 Frame = -3

Query: 83  FAYGQTSSGKTHTMEGKLHDPQLMGIIPRIAHDIFDHIYSMDENLEFHIKVSYFEIYLDK 142
           F        KTHTMEG L +  L GIIPRI  DIF++IY MDENLEFHIKVSYFEIY+DK
Sbjct: 528 FCLWSNVQWKTHTMEGVLGNESLQGIIPRIVQDIFNYIYGMDENLEFHIKVSYFEIYMDK 349

Query: 143 IRDLLDVSKTNLAVHEDKNRVPYVKGCTERFVSSPEEVMDVIDEGKANRHVAVTNMNEHS 202
           IRDLLDV+KTNL+VHEDKNRVPYVKGCTERFVSSPEEVM+V+DEGK+NRHVAVTNMNEHS
Sbjct: 348 IRDLLDVTKTNLSVHEDKNRVPYVKGCTERFVSSPEEVMEVVDEGKSNRHVAVTNMNEHS 169

Query: 203 SRSHSIFLINIKQENVETEKKLSGKLYLVDLAGSEKVSKTGAEGAVLDEAKNINKS 258
           SRSHS+FLI++KQENV++EKKL GKLYLVDLAGSEKVSKTGAEGAVLDEAKNIN+S
Sbjct: 168 SRSHSVFLIHVKQENVDSEKKLHGKLYLVDLAGSEKVSKTGAEGAVLDEAKNINRS 1

 Score = 80.5 bits (197), Expect = 3e-15,   Method: Composition-based stats.
 Identities = 39/55 (70%), Positives = 43/55 (78%)
 Frame = -1

Query: 41  IGQGKPYVFDRVLPPNTTQEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHT 95
           I +GK ++FD+VL PN TQE VY   AK IV DVL GYNGTIFAYGQTSSGK HT
Sbjct: 653 ICRGKVFMFDKVLKPNVTQEYVYTVTAKPIVADVLSGYNGTIFAYGQTSSGK-HT 492
>33215
          Length = 696

 Score =  181 bits (458), Expect = 2e-45,   Method: Compositional matrix adjust.
 Identities = 102/205 (49%), Positives = 132/205 (64%), Gaps = 5/205 (2%)
 Frame = +1

Query: 135 YFEIYLDKIRDLL--DVSKTNLAVHEDKNRVPYVKGCTERFVSSPEEVMDVIDEGKANRH 192
           Y EIY ++IRDLL  D SK  L +    +   YVK  +     S  E+  V++ G  NR 
Sbjct: 1   YLEIYQEEIRDLLSKDQSK-RLELKXRPDTGVYVKDLSSFVTKSVREIEHVMNVGNQNRS 177

Query: 193 VAVTNMNEHSSRSHSIFLINIKQENVETEKK---LSGKLYLVDLAGSEKVSKTGAEGAVL 249
           V  TNMNEHSSRSH+IF+I ++   +  + +     GKL +VDLAGSE+ +KTGA G  L
Sbjct: 178 VGATNMNEHSSRSHAIFIITVECSEIGADGENHIRVGKLNMVDLAGSERQAKTGATGDRL 357

Query: 250 DEAKNINKSLSALGNVISALAEGTKTHVPYRDSKMTRILQDSLGGNCRTTIVICCSPSVF 309
            EA  IN SLSAL NVISAL +   TH+PYRDSK+TR+LQDSLGGN +TT+V    P+ +
Sbjct: 358 KEATKINLSLSALSNVISALVDAKTTHIPYRDSKLTRLLQDSLGGNSKTTMVANIGPASY 537

Query: 310 NEAETKSTLMFGQRAKTIKNTVSVN 334
           N  ET +TL +  RAK+IKN   +N
Sbjct: 538 NFDETLTTLRYANRAKSIKNKPKIN 612
>12048
          Length = 1162

 Score =  166 bits (419), Expect = 6e-41,   Method: Compositional matrix adjust.
 Identities = 104/251 (41%), Positives = 140/251 (55%), Gaps = 10/251 (3%)
 Frame = +2

Query: 91  GKTHTMEGKLHDPQLMGIIPRIAHDIFDHIYSMDENLEFHIKVSYFEIYLDKIRDLLD-- 148
           GKT T+ G        G+IPR    I++      E L F + +SY EIY D   DLLD  
Sbjct: 416 GKTFTITGGAERYMDRGLIPRSLSYIYEQTEKNPE-LSFTVHISYLEIYNDSGYDLLDPK 592

Query: 149 --------VSKTNLAVHEDKNRVPYVKGCTERFVSSPEEVMDVIDEGKANRHVAVTNMNE 200
                   + K NL   ED ++  +++  +    +S EE ++++  G  NR +A T MN+
Sbjct: 593 HEAAKLEDLPKVNLL--EDSDQNIHLRNLSVHQANSEEEALNLLFLGDTNRMIAETPMNQ 766

Query: 201 HSSRSHSIFLINIKQENVETEKKLSGKLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLS 260
            SSRSH IF I+I      +      K +LVDLAGSE+V+KT   G +L EA+ IN SL 
Sbjct: 767 ASSRSHCIFTIHITTRETGSATIRRAKYHLVDLAGSERVAKTNVNGQLLTEARYINSSLH 946

Query: 261 ALGNVISALAEGTKTHVPYRDSKMTRILQDSLGGNCRTTIVICCSPSVFNEAETKSTLMF 320
            L  VI AL+E ++ HVPYR+S MT +L+DSLGGNC TT++  CS    N  E+ ST  F
Sbjct: 947 FLELVIIALSEKSRQHVPYRNSMMTSVLRDSLGGNCMTTMIATCSMEKRNMDESISTCRF 1126

Query: 321 GQRAKTIKNTV 331
            QR   IKN V
Sbjct: 1127AQRVAMIKNDV 1159

 Score = 52.8 bits (125), Expect = 6e-07,   Method: Compositional matrix adjust.
 Identities = 26/58 (44%), Positives = 35/58 (60%), Gaps = 7/58 (12%)
 Frame = +1

Query: 55  PNTTQEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGK---THTMEGKLH----DPQL 105
           P T Q++V+   AK ++ +VL+GYNGT+FAYGQT   +    H   G LH    DP L
Sbjct: 307 PKTNQDEVFQNVAKPVIDNVLQGYNGTVFAYGQTGRWQDLHHHWGSGTLHGSWTDPSL 480
>11818
          Length = 657

 Score =  105 bits (263), Expect(2) = 5e-34,   Method: Compositional matrix adjust.
 Identities = 70/182 (38%), Positives = 99/182 (54%), Gaps = 8/182 (4%)
 Frame = -1

Query: 90  SGKTHTMEGKL-----HDPQLMGIIPRIAHDIFDHIYSMDENLEFHIKVSYFEIYLDKIR 144
           SGKT+TM G       HD  L+GIIPRI  D+F+ I +   +  F + VSY EIY + + 
Sbjct: 657 SGKTYTMGGCYDAALSHDDDLVGIIPRILGDLFNGI-AERSDYTFKVTVSYLEIYNEDLL 481

Query: 145 DLLDVS--KTNLAVHEDKNRVPYVKGCTERFVSSPEEVMDVIDEGKANRHVAVTNMNEHS 202
           DLL +   +  L++ E+ N    +KG  E  V S E+ +  + +G  +R    T MN+ S
Sbjct: 480 DLLCLPSQRQPLSIREEMNGEIKIKGLKEVEVGSLEDTLMCLSQGARSRTTGATAMNDTS 301

Query: 203 SRSHSIFLINI-KQENVETEKKLSGKLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSA 261
           SRSH+IF ++I K +  +       K +LVDLAGSE+  KT AEG    E  NI  +   
Sbjct: 300 SRSHAIFTVHIEKSKKEDMNDHCIAKFHLVDLAGSERAKKTRAEGDRFKEGVNITVACLP 121

Query: 262 LG 263
            G
Sbjct: 120 WG 115

 Score = 58.2 bits (139), Expect(2) = 5e-34,   Method: Composition-based stats.
 Identities = 29/44 (65%), Positives = 34/44 (77%), Gaps = 2/44 (4%)
 Frame = -3

Query: 257 KSLSALGNVISALAEGTKT--HVPYRDSKMTRILQDSLGGNCRT 298
           + L ALGNVISAL E  +   H+PYRDSK+TR+LQDSLGGN  T
Sbjct: 136 RGLLALGNVISALGEDVQKRGHIPYRDSKLTRLLQDSLGGNSHT 5
>02896
          Length = 2076

 Score =  125 bits (315), Expect = 6e-29,   Method: Compositional matrix adjust.
 Identities = 66/172 (38%), Positives = 103/172 (59%), Gaps = 2/172 (1%)
 Frame = +1

Query: 165 YVKGCTERFVSSPEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQEN-VETEKK 223
           + +G       + EE ++++ EG+ NR +A  ++N  SSRSH IF + ++  + V++  K
Sbjct: 13  WSRGLASHLAQNEEEALNLLFEGETNRSIAAHSLNRMSSRSHCIFTVYLESRSRVQSSAK 192

Query: 224 LS-GKLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEGTKTHVPYRDS 282
            +  KL  VDLAGSE++ K+ +EG ++ EA  INKSLS L  V+ ALA+  + H+P+R S
Sbjct: 193 YTVSKLNFVDLAGSERIGKSKSEGKMVTEAMYINKSLSFLEQVVIALADKNRDHIPFRQS 372

Query: 283 KMTRILQDSLGGNCRTTIVICCSPSVFNEAETKSTLMFGQRAKTIKNTVSVN 334
           K+T  L+DS+GGNC T ++           ET STL F  R   + N  ++N
Sbjct: 373 KLTHYLKDSIGGNCNTVLIANVWGERAQLEETVSTLRFATRMMCVANEPAIN 528
>28434
          Length = 777

 Score =  113 bits (283), Expect = 3e-25,   Method: Compositional matrix adjust.
 Identities = 58/105 (55%), Positives = 71/105 (67%), Gaps = 2/105 (1%)
 Frame = +2

Query: 232 DLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEGT--KTHVPYRDSKMTRILQ 289
           DLAGSE+  +T AEG    E  NIN+ L ALGNVISAL E    + H+PYRDSK+TR+LQ
Sbjct: 62  DLAGSERAKRTRAEGDRFKEGVNINRGLLALGNVISALGEDVQKRGHIPYRDSKLTRLLQ 241

Query: 290 DSLGGNCRTTIVICCSPSVFNEAETKSTLMFGQRAKTIKNTVSVN 334
           DSLGGN  T +V C SP+  N  ET +TL +  RA+ IKN   +N
Sbjct: 242 DSLGGNSHTLMVACVSPADSNMEETLNTLRYADRARKIKNKPVIN 376
>38050
          Length = 809

 Score = 55.5 bits (132), Expect(3) = 2e-23,   Method: Composition-based stats.
 Identities = 28/57 (49%), Positives = 38/57 (66%), Gaps = 3/57 (5%)
 Frame = -1

Query: 246 GAVLDEAKNINKSLSALGNVISALAE---GTKTHVPYRDSKMTRILQDSLGGNCRTT 299
           G  L E   IN+SLS LGN ISALA+   G    VP+RDS +T++L+++LGG  R +
Sbjct: 449 GDRLKEGAAINQSLSCLGNCISALADKAGGKNVKVPFRDSALTKLLKNALGGTARLS 279

 Score = 54.3 bits (129), Expect(3) = 2e-23,   Method: Compositional matrix adjust.
 Identities = 36/85 (42%), Positives = 46/85 (54%), Gaps = 3/85 (3%)
 Frame = -2

Query: 165 YVKGCTERFVSSPEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQ--ENVETEK 222
           Y  G     V S E++   ++ G  NR VA TNMN  SSR+H+I  I   Q  +N   E+
Sbjct: 700 YADGLQVVPVVSYEDIEKKMEAGTTNRTVAATNMNATSSRAHTIVGITFMQKFKNAAGEE 521

Query: 223 KL-SGKLYLVDLAGSEKVSKTGAEG 246
              S  + LVDLAGSE+   TGA G
Sbjct: 520 TTKSALINLVDLAGSERADSTGATG 446

 Score = 38.5 bits (88), Expect(3) = 2e-23,   Method: Compositional matrix adjust.
 Identities = 19/42 (45%), Positives = 23/42 (54%)
 Frame = -3

Query: 293 GGNCRTTIVICCSPSVFNEAETKSTLMFGQRAKTIKNTVSVN 334
           G N +T +V   SP+  N  ET STL +  RAK IK    VN
Sbjct: 300 GWNSKTIMVAALSPADINYEETLSTLRYADRAKQIKTKAMVN 175
>14618
          Length = 724

 Score =  102 bits (253), Expect = 1e-21,   Method: Compositional matrix adjust.
 Identities = 77/225 (34%), Positives = 108/225 (48%), Gaps = 30/225 (13%)
 Frame = -2

Query: 8   SIKVMCRFRPL-------------------NEAEILRGDKFIPKFKGEETVVI---GQGK 45
           +I+V CR RPL                   ++ ++L  D+       E T+     G  K
Sbjct: 669 NIRVFCRVRPLLGEEAATNDGVIHHINFPDSDNKVLELDRLTEMSMNESTLYNNRRGNNK 490

Query: 46  -PYVFDRVLPPNTTQEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKL-HDP 103
             + FDRV  P+ TQ+ V+   + Q+V+  L+GYN  IFAYGQT SGKT+TMEG L  D 
Sbjct: 489 YEFSFDRVFHPDNTQQDVFEEIS-QLVQSALDGYNVCIFAYGQTGSGKTYTMEGGLVGDE 313

Query: 104 QLMGIIPRIAHDIFDHIYSM-DENLEFHIKVSYFEIYLDKIRDLLDVSKTNLAVHEDK-- 160
              G+IPR    IF     + D+  ++    S+ EIY + I DLL  +K     HE +  
Sbjct: 312 DTKGMIPRAVSQIFSTARELQDKGWQYKFTTSFVEIYNEMIGDLLSSNKXKNVKHEIRMA 133

Query: 161 ---NRVPYVKGCTERFVSSPEEVMDVIDEGKANRHVAVTNMNEHS 202
              N V  V   T   V+S  E+  ++ +   NR VA T  NE S
Sbjct: 132 GRDNNVA-VTNLTTVDVTSQHEIAKLLRQASENRAVAATKCNERS 1
>15043
          Length = 973

 Score = 95.1 bits (235), Expect = 1e-19,   Method: Compositional matrix adjust.
 Identities = 53/153 (34%), Positives = 89/153 (58%), Gaps = 1/153 (0%)
 Frame = +2

Query: 187 GKANRHVAVTNMNEHSSRSHSIFLINIKQENVETEK-KLSGKLYLVDLAGSEKVSKTGAE 245
           G+  R +  T++  H +R+H++F I ++Q+  ++ K  +   + LV+LAG E    T  +
Sbjct: 26  GRRARRMGATDIKAHRARAHAVFTITVEQKERQSSKVGVRANIMLVELAGCEAADAT--D 199

Query: 246 GAVLDEAKNINKSLSALGNVISALAEGTKTHVPYRDSKMTRILQDSLGGNCRTTIVICCS 305
             +L   + +   L ALG+     ++    HVPYR+S +TR+LQD+LGGN  T +++  S
Sbjct: 200 PKILAGTQGVVNVLKALGD-----SKQIGGHVPYRESLVTRLLQDTLGGNAMTLMLVTVS 364

Query: 306 PSVFNEAETKSTLMFGQRAKTIKNTVSVNLELT 338
           P   +   T+S L +GQ AKT+KN   +NL+ T
Sbjct: 365 PLDKSYQTTQSALQYGQFAKTVKNHARMNLDDT 463
>34477
          Length = 811

 Score = 82.8 bits (203), Expect = 7e-16,   Method: Compositional matrix adjust.
 Identities = 50/110 (45%), Positives = 64/110 (58%), Gaps = 1/110 (0%)
 Frame = +3

Query: 226 GKLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEGTKTHV-PYRDSKM 284
           GKL+LVDLAGSE+ +KTGA G  L EA  IN SLS LGNVIS +  G + H  P ++ + 
Sbjct: 195 GKLHLVDLAGSERQAKTGATGQRLKEATKINLSLSTLGNVIS-VPGGRQEHTHPLQELQA 371

Query: 285 TRILQDSLGGNCRTTIVICCSPSVFNEAETKSTLMFGQRAKTIKNTVSVN 334
                   G   +T +V    P+ +N  ET STL +  RAK IKN   +N
Sbjct: 372 HSPAAGLPGRQLQTVMVANMGPADYNYDETISTLRYANRAKNIKNKAKIN 521

 Score = 70.5 bits (171), Expect = 3e-12,   Method: Composition-based stats.
 Identities = 44/142 (30%), Positives = 70/142 (49%), Gaps = 7/142 (4%)
 Frame = +1

Query: 165 YVKGCTERFVSSPEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETEKKL 224
           YVK  +   V++ +++  ++  G  NR V  TNMN HSSRSH+IF + ++     +EK  
Sbjct: 4   YVKDLSAFVVNNADDMDRIMTLGNKNRSVGSTNMNMHSSRSHAIFTVTVEC----SEKGA 171

Query: 225 SGKLYLV-------DLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEGTKTHV 277
           +G    V          G     +   + +   +                +L +G  TH+
Sbjct: 172 TGSSMYVWANCTWWTWXGQRDKPRQEPQASA*RKRPRSTCLCQLWAM*YRSLVDGKSTHI 351

Query: 278 PYRDSKMTRILQDSLGGNCRTT 299
           PYR+SK+TR+LQDSLGGN + +
Sbjct: 352 PYRNSKLTRLLQDSLGGNSKLS 417
>34899
          Length = 564

 Score = 78.2 bits (191), Expect = 2e-14,   Method: Compositional matrix adjust.
 Identities = 46/156 (29%), Positives = 78/156 (50%)
 Frame = +3

Query: 49  FDRVLPPNTTQEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGI 108
            D    P+    Q+Y      +V+  LEGYN TI A+G T SGK+  M G   + Q +G+
Sbjct: 6   LDGAYGPDAKNGQIYQEKCDSMVQRALEGYNVTIMAFGATGSGKSFLMNG---NDQEIGV 176

Query: 109 IPRIAHDIFDHIYSMDENLEFHIKVSYFEIYLDKIRDLLDVSKTNLAVHEDKNRVPYVKG 168
            P +   +F H+     N E  +  S+ EI  +K+ DLL+     +AV +   +  +V G
Sbjct: 177 APMVIQQLFQHL-RQRSNKESMVTASFVEILDEKMTDLLNPHNRPMAVRQHVIKGIFVDG 353

Query: 169 CTERFVSSPEEVMDVIDEGKANRHVAVTNMNEHSSR 204
            +E    + EE+  + ++G+  R +  T++  H +R
Sbjct: 354 LSEMVARTGEELSQLYEQGRRARRMGATDIKAHRAR 461
>17748
          Length = 621

 Score = 69.7 bits (169), Expect = 5e-12,   Method: Compositional matrix adjust.
 Identities = 49/140 (35%), Positives = 74/140 (52%), Gaps = 7/140 (5%)
 Frame = -3

Query: 55  PNTTQEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLH-----DPQLMGII 109
           P+TT +    +  K     + +GYN T+ AYGQT SGKT +M G        D + MGII
Sbjct: 433 PSTTNKMCTRSQHKL**PALFKGYNATVLAYGQTGSGKTFSMGGCYEASLKLDEEAMGII 254

Query: 110 PRIAHDIFDHIYSMDENLEFHIKVSYFEIY-LDKIRDLLDVS-KTNLAVHEDKNRVPYVK 167
           PRI  D+F+ I    ++  F + VSY EIY  + +  L  +S +  L + E+ N    +K
Sbjct: 253 PRIIKDLFNGIQERPDH-TFKVTVSYLEIYNEELLBLLCPLSQRQPLTIREELNGEIKIK 77

Query: 168 GCTERFVSSPEEVMDVIDEG 187
           G  E  V S ++ +D + +G
Sbjct: 76  GLKEVTVGSVDDTLDCLSQG 17
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|19527170|ref|NP_598711.1| KDEL endoplasmic reticulum
protein retention receptor 1 [Mus musculus]
         (212 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

38437                                                                 291   7e-84
26608                                                                  83   9e-17
20520                                                                  27   4.4  
>38437
          Length = 2630

 Score =  291 bits (745), Expect(2) = 7e-84,   Method: Compositional matrix adjust.
 Identities = 140/179 (78%), Positives = 160/179 (89%)
 Frame = -1

Query: 34   GKSQVLFAVVFTARYLDLFTNYISLYNTCMKVVYIACSFTTVWMIYSKFKATYDGNHDTF 93
             K + +FAVVF  RYLDLF+++IS YNT MK+ ++  S  TV+++Y KF+ATYD NHDTF
Sbjct: 2501 AKXKSVFAVVFLTRYLDLFSSFISPYNTIMKLFFVGSSVFTVYLMYVKFRATYDANHDTF 2322

Query: 94   RVEFLVVPTAILAFLVNHDFTPLEILWTFSIYLESVAILPQLFMVSKTGEAETITSHYLF 153
            RVEFLVVP A LAFLVNH+F+P+EILWTFSIYLESVAILPQLFMVSKTGEAETITSHYLF
Sbjct: 2321 RVEFLVVPVAGLAFLVNHEFSPMEILWTFSIYLESVAILPQLFMVSKTGEAETITSHYLF 2142

Query: 154  ALGVYRTLYLFNWIWRYHFEGFFDLIAIVAGLVQTVLYCDFFYLYITKVLKGKKLSLPA 212
            ALG YR LY+FNWI+RY+FEGFFDLIA+VAG VQT+LYCDFFYLYITKVLKGKKLSLPA
Sbjct: 2141 ALGSYRCLYIFNWIYRYYFEGFFDLIAVVAGCVQTILYCDFFYLYITKVLKGKKLSLPA 1965

 Score = 36.6 bits (83), Expect(2) = 7e-84,   Method: Compositional matrix adjust.
 Identities = 16/38 (42%), Positives = 20/38 (52%)
 Frame = -3

Query: 1    MNLFRFXXXXXXXXXXXXXXXXXWKSRSCAGISGKSQV 38
            MN+FR                  WK+RSCAGISGK+Q+
Sbjct: 2601 MNIFRLIGDMSHLLAIILLLLKMWKTRSCAGISGKAQI 2488
>26608
          Length = 738

 Score = 82.8 bits (203), Expect = 9e-17,   Method: Compositional matrix adjust.
 Identities = 37/73 (50%), Positives = 52/73 (71%)
 Frame = +2

Query: 132 LPQLFMVSKTGEAETITSHYLFALGVYRTLYLFNWIWRYHFEGFFDLIAIVAGLVQTVLY 191
           LPQ FM+ +TG+ +    HYLFA G YR  Y+FNW++RY +EGF+D ++I +G +QT  Y
Sbjct: 2   LPQFFMIYRTGDMDMFMYHYLFAHGFYRAYYIFNWVYRYTYEGFYDNVSIWSGSIQTAFY 181

Query: 192 CDFFYLYITKVLK 204
           C  ++LY TK LK
Sbjct: 182 C--YFLYSTKFLK 214
>20520
          Length = 1621

 Score = 27.3 bits (59), Expect = 4.4,   Method: Compositional matrix adjust.
 Identities = 11/16 (68%), Positives = 14/16 (87%)
 Frame = +1

Query: 109 VNHDFTPLEILWTFSI 124
           VN++FTP+E LWT SI
Sbjct: 859 VNNEFTPVERLWTKSI 906
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|61657921|ref|NP_032474.2| kinesin family member 5B
[Mus musculus]
         (963 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

13148                                                                 308   8e-84
33215                                                                 175   7e-44
12048                                                                 161   1e-39
11818                                                                 103   2e-32
02896                                                                 115   1e-25
28434                                                                 112   8e-25
38050                                                                  55   1e-22
14618                                                                 102   1e-21
15043                                                                  93   6e-19
34477                                                                  83   6e-16
17748                                                                  75   1e-13
34899                                                                  74   2e-13
36593                                                                  37   0.048
>13148
          Length = 653

 Score =  308 bits (788), Expect = 8e-84,   Method: Compositional matrix adjust.
 Identities = 145/176 (82%), Positives = 156/176 (88%)
 Frame = -3

Query: 82  FAYGQTSSGKTHTMEGKLHDPEGMGIIPRIVQDIFNYIYSMDENLEFHIKVSYFEIYLDK 141
           F        KTHTMEG L +    GIIPRIVQDIFNYIY MDENLEFHIKVSYFEIY+DK
Sbjct: 528 FCLWSNVQWKTHTMEGVLGNESLQGIIPRIVQDIFNYIYGMDENLEFHIKVSYFEIYMDK 349

Query: 142 IRDLLDVSKTNLSVHEDKNRVPYVKGCTERFVCSPDEVMDTIDEGKSNRHVAVTNMNEHS 201
           IRDLLDV+KTNLSVHEDKNRVPYVKGCTERFV SP+EVM+ +DEGKSNRHVAVTNMNEHS
Sbjct: 348 IRDLLDVTKTNLSVHEDKNRVPYVKGCTERFVSSPEEVMEVVDEGKSNRHVAVTNMNEHS 169

Query: 202 SRSHSIFLINVKQENTQTEQKLSGKLYLVDLAGSEKVSKTGAEGAVLDEAKNINKS 257
           SRSHS+FLI+VKQEN  +E+KL GKLYLVDLAGSEKVSKTGAEGAVLDEAKNIN+S
Sbjct: 168 SRSHSVFLIHVKQENVDSEKKLHGKLYLVDLAGSEKVSKTGAEGAVLDEAKNINRS 1

 Score = 67.8 bits (164), Expect = 2e-11,   Method: Composition-based stats.
 Identities = 33/51 (64%), Positives = 38/51 (74%)
 Frame = -1

Query: 44  KPYAFDRVFQSSTSQEQVYNDCAKKIVKDVLEGYNGTIFAYGQTSSGKTHT 94
           K + FD+V + + +QE VY   AK IV DVL GYNGTIFAYGQTSSGK HT
Sbjct: 641 KVFMFDKVLKPNVTQEYVYTVTAKPIVADVLSGYNGTIFAYGQTSSGK-HT 492
>33215
          Length = 696

 Score =  175 bits (444), Expect = 7e-44,   Method: Compositional matrix adjust.
 Identities = 104/205 (50%), Positives = 133/205 (64%), Gaps = 6/205 (2%)
 Frame = +1

Query: 134 YFEIYLDKIRDLL--DVSKTNLSVHEDKNRVPYVKGCTERFVCSPDEVMDTIDEGKSNRH 191
           Y EIY ++IRDLL  D SK  L +    +   YVK  +     S  E+   ++ G  NR 
Sbjct: 1   YLEIYQEEIRDLLSKDQSK-RLELKXRPDTGVYVKDLSSFVTKSVREIEHVMNVGNQNRS 177

Query: 192 VAVTNMNEHSSRSHSIFLINVK--QENTQTEQKLS-GKLYLVDLAGSEKVSKTGAEGAVL 248
           V  TNMNEHSSRSH+IF+I V+  +     E  +  GKL +VDLAGSE+ +KTGA G  L
Sbjct: 178 VGATNMNEHSSRSHAIFIITVECSEIGADGENHIRVGKLNMVDLAGSERQAKTGATGDRL 357

Query: 249 DEAKNINKSLSALGNVISALAEG-STYVPYRDSKMTRILQDSLGGNCRTTIVICCSPSSY 307
            EA  IN SLSAL NVISAL +  +T++PYRDSK+TR+LQDSLGGN +TT+V    P+SY
Sbjct: 358 KEATKINLSLSALSNVISALVDAKTTHIPYRDSKLTRLLQDSLGGNSKTTMVANIGPASY 537

Query: 308 NESETKSTLLFGQRAKTIKNTVCVN 332
           N  ET +TL +  RAK+IKN   +N
Sbjct: 538 NFDETLTTLRYANRAKSIKNKPKIN 612
>12048
          Length = 1162

 Score =  161 bits (407), Expect = 1e-39,   Method: Compositional matrix adjust.
 Identities = 105/254 (41%), Positives = 141/254 (55%), Gaps = 14/254 (5%)
 Frame = +2

Query: 90  GKTHTMEGKLHDPEGMGIIPRIVQDIFNYIYSMDEN---LEFHIKVSYFEIYLDKIRDLL 146
           GKT T+ G        G+IPR +    +YIY   E    L F + +SY EIY D   DLL
Sbjct: 416 GKTFTITGGAERYMDRGLIPRSL----SYIYEQTEKNPELSFTVHISYLEIYNDSGYDLL 583

Query: 147 D----------VSKTNLSVHEDKNRVPYVKGCTERFVCSPDEVMDTIDEGKSNRHVAVTN 196
           D          + K NL   ED ++  +++  +     S +E ++ +  G +NR +A T 
Sbjct: 584 DPKHEAAKLEDLPKVNLL--EDSDQNIHLRNLSVHQANSEEEALNLLFLGDTNRMIAETP 757

Query: 197 MNEHSSRSHSIFLINVKQENTQTEQKLSGKLYLVDLAGSEKVSKTGAEGAVLDEAKNINK 256
           MN+ SSRSH IF I++    T +      K +LVDLAGSE+V+KT   G +L EA+ IN 
Sbjct: 758 MNQASSRSHCIFTIHITTRETGSATIRRAKYHLVDLAGSERVAKTNVNGQLLTEARYINS 937

Query: 257 SLSALGNVISALAEGS-TYVPYRDSKMTRILQDSLGGNCRTTIVICCSPSSYNESETKST 315
           SL  L  VI AL+E S  +VPYR+S MT +L+DSLGGNC TT++  CS    N  E+ ST
Sbjct: 938 SLHFLELVIIALSEKSRQHVPYRNSMMTSVLRDSLGGNCMTTMIATCSMEKRNMDESIST 1117

Query: 316 LLFGQRAKTIKNTV 329
             F QR   IKN V
Sbjct: 1118CRFAQRVAMIKNDV 1159

 Score = 51.6 bits (122), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 23/53 (43%), Positives = 35/53 (66%), Gaps = 3/53 (5%)
 Frame = +1

Query: 51  VFQSSTSQEQVYNDCAKKIVKDVLEGYNGTIFAYGQTSSGK---THTMEGKLH 100
           +F   T+Q++V+ + AK ++ +VL+GYNGT+FAYGQT   +    H   G LH
Sbjct: 298 MF*PKTNQDEVFQNVAKPVIDNVLQGYNGTVFAYGQTGRWQDLHHHWGSGTLH 456
>11818
          Length = 657

 Score =  103 bits (258), Expect(2) = 2e-32,   Method: Compositional matrix adjust.
 Identities = 69/182 (37%), Positives = 99/182 (54%), Gaps = 8/182 (4%)
 Frame = -1

Query: 89  SGKTHTMEGKL-----HDPEGMGIIPRIVQDIFNYIYSMDENLEFHIKVSYFEIYLDKIR 143
           SGKT+TM G       HD + +GIIPRI+ D+FN I +   +  F + VSY EIY + + 
Sbjct: 657 SGKTYTMGGCYDAALSHDDDLVGIIPRILGDLFNGI-AERSDYTFKVTVSYLEIYNEDLL 481

Query: 144 DLLDVS--KTNLSVHEDKNRVPYVKGCTERFVCSPDEVMDTIDEGKSNRHVAVTNMNEHS 201
           DLL +   +  LS+ E+ N    +KG  E  V S ++ +  + +G  +R    T MN+ S
Sbjct: 480 DLLCLPSQRQPLSIREEMNGEIKIKGLKEVEVGSLEDTLMCLSQGARSRTTGATAMNDTS 301

Query: 202 SRSHSIFLINV-KQENTQTEQKLSGKLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSA 260
           SRSH+IF +++ K +          K +LVDLAGSE+  KT AEG    E  NI  +   
Sbjct: 300 SRSHAIFTVHIEKSKKEDMNDHCIAKFHLVDLAGSERAKKTRAEGDRFKEGVNITVACLP 121

Query: 261 LG 262
            G
Sbjct: 120 WG 115

 Score = 54.7 bits (130), Expect(2) = 2e-32,   Method: Composition-based stats.
 Identities = 28/44 (63%), Positives = 33/44 (75%), Gaps = 3/44 (6%)
 Frame = -3

Query: 256 KSLSALGNVISALAEGST---YVPYRDSKMTRILQDSLGGNCRT 296
           + L ALGNVISAL E      ++PYRDSK+TR+LQDSLGGN  T
Sbjct: 136 RGLLALGNVISALGEDVQKRGHIPYRDSKLTRLLQDSLGGNSHT 5
>02896
          Length = 2076

 Score =  115 bits (287), Expect = 1e-25,   Method: Compositional matrix adjust.
 Identities = 64/172 (37%), Positives = 101/172 (58%), Gaps = 3/172 (1%)
 Frame = +1

Query: 164 YVKGCTERFVCSPDEVMDTIDEGKSNRHVAVTNMNEHSSRSHSIFLINVKQEN-TQTEQK 222
           + +G       + +E ++ + EG++NR +A  ++N  SSRSH IF + ++  +  Q+  K
Sbjct: 13  WSRGLASHLAQNEEEALNLLFEGETNRSIAAHSLNRMSSRSHCIFTVYLESRSRVQSSAK 192

Query: 223 LS-GKLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEGST-YVPYRDS 280
            +  KL  VDLAGSE++ K+ +EG ++ EA  INKSLS L  V+ ALA+ +  ++P+R S
Sbjct: 193 YTVSKLNFVDLAGSERIGKSKSEGKMVTEAMYINKSLSFLEQVVIALADKNRDHIPFRQS 372

Query: 281 KMTRILQDSLGGNCRTTIVICCSPSSYNESETKSTLLFGQRAKTIKNTVCVN 332
           K+T  L+DS+GGNC T ++           ET STL F  R   + N   +N
Sbjct: 373 KLTHYLKDSIGGNCNTVLIANVWGERAQLEETVSTLRFATRMMCVANEPAIN 528
>28434
          Length = 777

 Score =  112 bits (280), Expect = 8e-25,   Method: Compositional matrix adjust.
 Identities = 57/105 (54%), Positives = 70/105 (66%), Gaps = 3/105 (2%)
 Frame = +2

Query: 231 DLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEG---STYVPYRDSKMTRILQ 287
           DLAGSE+  +T AEG    E  NIN+ L ALGNVISAL E      ++PYRDSK+TR+LQ
Sbjct: 62  DLAGSERAKRTRAEGDRFKEGVNINRGLLALGNVISALGEDVQKRGHIPYRDSKLTRLLQ 241

Query: 288 DSLGGNCRTTIVICCSPSSYNESETKSTLLFGQRAKTIKNTVCVN 332
           DSLGGN  T +V C SP+  N  ET +TL +  RA+ IKN   +N
Sbjct: 242 DSLGGNSHTLMVACVSPADSNMEETLNTLRYADRARKIKNKPVIN 376
>38050
          Length = 809

 Score = 55.1 bits (131), Expect(3) = 1e-22,   Method: Compositional matrix adjust.
 Identities = 35/85 (41%), Positives = 47/85 (55%), Gaps = 3/85 (3%)
 Frame = -2

Query: 164 YVKGCTERFVCSPDEVMDTIDEGKSNRHVAVTNMNEHSSRSHSIFLINVKQ--ENTQTEQ 221
           Y  G     V S +++   ++ G +NR VA TNMN  SSR+H+I  I   Q  +N   E+
Sbjct: 700 YADGLQVVPVVSYEDIEKKMEAGTTNRTVAATNMNATSSRAHTIVGITFMQKFKNAAGEE 521

Query: 222 KL-SGKLYLVDLAGSEKVSKTGAEG 245
              S  + LVDLAGSE+   TGA G
Sbjct: 520 TTKSALINLVDLAGSERADSTGATG 446

 Score = 51.2 bits (121), Expect(3) = 1e-22,   Method: Composition-based stats.
 Identities = 27/57 (47%), Positives = 38/57 (66%), Gaps = 4/57 (7%)
 Frame = -1

Query: 245 GAVLDEAKNINKSLSALGNVISALAEGS----TYVPYRDSKMTRILQDSLGGNCRTT 297
           G  L E   IN+SLS LGN ISALA+ +      VP+RDS +T++L+++LGG  R +
Sbjct: 449 GDRLKEGAAINQSLSCLGNCISALADKAGGKNVKVPFRDSALTKLLKNALGGTARLS 279

 Score = 39.7 bits (91), Expect(3) = 1e-22,   Method: Compositional matrix adjust.
 Identities = 19/42 (45%), Positives = 23/42 (54%)
 Frame = -3

Query: 291 GGNCRTTIVICCSPSSYNESETKSTLLFGQRAKTIKNTVCVN 332
           G N +T +V   SP+  N  ET STL +  RAK IK    VN
Sbjct: 300 GWNSKTIMVAALSPADINYEETLSTLRYADRAKQIKTKAMVN 175
>14618
          Length = 724

 Score =  102 bits (253), Expect = 1e-21,   Method: Compositional matrix adjust.
 Identities = 76/225 (33%), Positives = 107/225 (47%), Gaps = 31/225 (13%)
 Frame = -2

Query: 8   NIKVMCRFRPL--NESEVNRGDKYVAKFQGEDTVMI----------------------AS 43
           NI+V CR RPL   E+  N G  +   F   D  ++                        
Sbjct: 669 NIRVFCRVRPLLGEEAATNDGVIHHINFPDSDNKVLELDRLTEMSMNESTLYNNRRGNNK 490

Query: 44  KPYAFDRVFQSSTSQEQVYNDCAKKIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKL-HDP 102
             ++FDRVF    +Q+ V+ + ++ +V+  L+GYN  IFAYGQT SGKT+TMEG L  D 
Sbjct: 489 YEFSFDRVFHPDNTQQDVFEEISQ-LVQSALDGYNVCIFAYGQTGSGKTYTMEGGLVGDE 313

Query: 103 EGMGIIPRIVQDIFNYIYSM-DENLEFHIKVSYFEIYLDKIRDLLDVSKTNLSVHEDK-- 159
           +  G+IPR V  IF+    + D+  ++    S+ EIY + I DLL  +K     HE +  
Sbjct: 312 DTKGMIPRAVSQIFSTARELQDKGWQYKFTTSFVEIYNEMIGDLLSSNKXKNVKHEIRMA 133

Query: 160 ---NRVPYVKGCTERFVCSPDEVMDTIDEGKSNRHVAVTNMNEHS 201
              N V  V   T   V S  E+   + +   NR VA T  NE S
Sbjct: 132 GRDNNVA-VTNLTTVDVTSQHEIAKLLRQASENRAVAATKCNERS 1
>15043
          Length = 973

 Score = 92.8 bits (229), Expect = 6e-19,   Method: Compositional matrix adjust.
 Identities = 52/152 (34%), Positives = 88/152 (57%), Gaps = 1/152 (0%)
 Frame = +2

Query: 186 GKSNRHVAVTNMNEHSSRSHSIFLINVKQENTQTEQ-KLSGKLYLVDLAGSEKVSKTGAE 244
           G+  R +  T++  H +R+H++F I V+Q+  Q+ +  +   + LV+LAG E    T  +
Sbjct: 26  GRRARRMGATDIKAHRARAHAVFTITVEQKERQSSKVGVRANIMLVELAGCEAADATDPK 205

Query: 245 GAVLDEAKNINKSLSALGNVISALAEGSTYVPYRDSKMTRILQDSLGGNCRTTIVICCSP 304
             +L   + +   L ALG+      +   +VPYR+S +TR+LQD+LGGN  T +++  SP
Sbjct: 206 --ILAGTQGVVNVLKALGDS----KQIGGHVPYRESLVTRLLQDTLGGNAMTLMLVTVSP 367

Query: 305 SSYNESETKSTLLFGQRAKTIKNTVCVNVELT 336
              +   T+S L +GQ AKT+KN   +N++ T
Sbjct: 368 LDKSYQTTQSALQYGQFAKTVKNHARMNLDDT 463
>34477
          Length = 811

 Score = 82.8 bits (203), Expect = 6e-16,   Method: Compositional matrix adjust.
 Identities = 54/117 (46%), Positives = 64/117 (54%), Gaps = 9/117 (7%)
 Frame = +3

Query: 225 GKLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEGSTYVPYRDSKMTR 284
           GKL+LVDLAGSE+ +KTGA G  L EA  IN SLS LGNVIS        VP    + T 
Sbjct: 195 GKLHLVDLAGSERQAKTGATGQRLKEATKINLSLSTLGNVIS--------VPGGRQEHTH 350

Query: 285 ILQD--------SLGG-NCRTTIVICCSPSSYNESETKSTLLFGQRAKTIKNTVCVN 332
            LQ+         L G   +T +V    P+ YN  ET STL +  RAK IKN   +N
Sbjct: 351 PLQELQAHSPAAGLPGRQLQTVMVANMGPADYNYDETISTLRYANRAKNIKNKAKIN 521

 Score = 62.8 bits (151), Expect = 6e-10,   Method: Composition-based stats.
 Identities = 43/138 (31%), Positives = 67/138 (48%), Gaps = 4/138 (2%)
 Frame = +1

Query: 164 YVKGCTERFVCSPDEVMDTIDEGKSNRHVAVTNMNEHSSRSHSIFLINV---KQENTQTE 220
           YVK  +   V + D++   +  G  NR V  TNMN HSSRSH+IF + V   ++  T + 
Sbjct: 4   YVKDLSAFVVNNADDMDRIMTLGNKNRSVGSTNMNMHSSRSHAIFTVTVECSEKGATGSS 183

Query: 221 QKLSGKLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEG-STYVPYRD 279
             +          G     +   + +   +                +L +G ST++PYR+
Sbjct: 184 MYVWANCTWWTWXGQRDKPRQEPQASA*RKRPRSTCLCQLWAM*YRSLVDGKSTHIPYRN 363

Query: 280 SKMTRILQDSLGGNCRTT 297
           SK+TR+LQDSLGGN + +
Sbjct: 364 SKLTRLLQDSLGGNSKLS 417
>17748
          Length = 621

 Score = 75.5 bits (184), Expect = 1e-13,   Method: Compositional matrix adjust.
 Identities = 49/125 (39%), Positives = 71/125 (56%), Gaps = 7/125 (5%)
 Frame = -3

Query: 73  VLEGYNGTIFAYGQTSSGKTHTMEGKLH-----DPEGMGIIPRIVQDIFNYIYSMDENLE 127
           + +GYN T+ AYGQT SGKT +M G        D E MGIIPRI++D+FN I    ++  
Sbjct: 376 LFKGYNATVLAYGQTGSGKTFSMGGCYEASLKLDEEAMGIIPRIIKDLFNGIQERPDH-T 200

Query: 128 FHIKVSYFEIY-LDKIRDLLDVS-KTNLSVHEDKNRVPYVKGCTERFVCSPDEVMDTIDE 185
           F + VSY EIY  + +  L  +S +  L++ E+ N    +KG  E  V S D+ +D + +
Sbjct: 199 FKVTVSYLEIYNEELLBLLCPLSQRQPLTIREELNGEIKIKGLKEVTVGSVDDTLDCLSQ 20

Query: 186 GKSNR 190
           G   R
Sbjct: 19  GAQLR 5
>34899
          Length = 564

 Score = 74.3 bits (181), Expect = 2e-13,   Method: Compositional matrix adjust.
 Identities = 44/157 (28%), Positives = 81/157 (51%)
 Frame = +3

Query: 47  AFDRVFQSSTSQEQVYNDCAKKIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPEGMG 106
           + D  +       Q+Y +    +V+  LEGYN TI A+G T SGK+  M G  +D E +G
Sbjct: 3   SLDGAYGPDAKNGQIYQEKCDSMVQRALEGYNVTIMAFGATGSGKSFLMNG--NDQE-IG 173

Query: 107 IIPRIVQDIFNYIYSMDENLEFHIKVSYFEIYLDKIRDLLDVSKTNLSVHEDKNRVPYVK 166
           + P ++Q +F ++     N E  +  S+ EI  +K+ DLL+     ++V +   +  +V 
Sbjct: 174 VAPMVIQQLFQHL-RQRSNKESMVTASFVEILDEKMTDLLNPHNRPMAVRQHVIKGIFVD 350

Query: 167 GCTERFVCSPDEVMDTIDEGKSNRHVAVTNMNEHSSR 203
           G +E    + +E+    ++G+  R +  T++  H +R
Sbjct: 351 GLSEMVARTGEELSQLYEQGRRARRMGATDIKAHRAR 461
>36593
          Length = 466

 Score = 36.6 bits (83), Expect = 0.048,   Method: Composition-based stats.
 Identities = 18/41 (43%), Positives = 27/41 (65%)
 Frame = +1

Query: 281 KMTRILQDSLGGNCRTTIVICCSPSSYNESETKSTLLFGQR 321
           K+T +LQ+SLGGN +T + +  SP   N SET ++L F  +
Sbjct: 1   KLTYLLQNSLGGNSKTLMFVNVSPKEENFSETLNSLRFATK 123
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|21313476|ref|NP_079811.1| SAR1a gene homolog 2 [Mus
musculus]
         (198 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

11378                                                                 304   1e-83
15662                                                                 184   1e-47
18949                                                                 131   2e-31
09827                                                                 100   4e-22
08153                                                                  96   7e-21
10862                                                                  72   5e-17
33605                                                                  70   7e-13
18208                                                                  61   4e-10
15973                                                                  55   1e-08
11965                                                                  38   0.003
32860                                                                  37   0.006
36734                                                                  35   0.022
19006                                                                  33   0.081
19506                                                                  33   0.088
29196                                                                  33   0.11 
26083                                                                  30   0.58 
22530                                                                  29   1.2  
03745                                                                  28   2.5  
27645                                                                  27   5.8  
06379                                                                  27   6.8  
>11378
          Length = 1688

 Score =  304 bits (779), Expect = 1e-83,   Method: Compositional matrix adjust.
 Identities = 144/196 (73%), Positives = 166/196 (84%)
 Frame = +3

Query: 3   FIFDWIYSGFSSVLQFLGLYKKSGKLVFLGLDNAGKTTLLHMLKDDRLGQHVPTLHPTSE 62
           F+++W    F  +L FLGLYKKSGKLVFLGLDNAGKTTLLHMLKDD++ QHVPTLHPTSE
Sbjct: 267 FLWNW----FQDMLSFLGLYKKSGKLVFLGLDNAGKTTLLHMLKDDKMAQHVPTLHPTSE 434

Query: 63  ELTIAGMTFTTFDLGGHVQARRVWKNYLPAINGIVFLVDCADHERLLESKEELDSLMTDE 122
           EL++ GM FTTFDLGGH QARRVWK+Y PA++GIVFLVD  D ERL+E+K ELDSLMTDE
Sbjct: 435 ELSMGGMRFTTFDLGGHRQARRVWKDYFPAVDGIVFLVDVHDRERLVEAKAELDSLMTDE 614

Query: 123 TIANVPILILGNKIDRPEAISEERLREMFGLYGQTTGKGSVSLKELNARPLEVFMCSVLK 182
            +AN PIL+LGNKID+P A SEE +R  FGL   TTGKG+V+  EL  RP+E+FMCSVLK
Sbjct: 615 QVANAPILVLGNKIDKPGAASEEEIRHWFGLNSLTTGKGTVARGELPGRPMELFMCSVLK 794

Query: 183 RQGYGEGFRWMAQYID 198
           RQGYGEGFRWMAQYI+
Sbjct: 795 RQGYGEGFRWMAQYIN 842
>15662
          Length = 455

 Score =  184 bits (468), Expect = 1e-47,   Method: Compositional matrix adjust.
 Identities = 85/118 (72%), Positives = 99/118 (83%)
 Frame = +2

Query: 81  QARRVWKNYLPAINGIVFLVDCADHERLLESKEELDSLMTDETIANVPILILGNKIDRPE 140
           QARRVWK+Y PA++GIVFLVD  D ER +E+K ELDSLMTDE +AN PIL+LGNKID+P 
Sbjct: 2   QARRVWKDYFPAVDGIVFLVDVHDRERFVEAKAELDSLMTDEQVANAPILVLGNKIDKPG 181

Query: 141 AISEERLREMFGLYGQTTGKGSVSLKELNARPLEVFMCSVLKRQGYGEGFRWMAQYID 198
           A SE+ +R  FGL+  TTGKG+VS  EL  RPLE+FMCSVLKRQGYGEGFRWMAQYI+
Sbjct: 182 AASEDEIRHWFGLHSLTTGKGTVSRGELPGRPLELFMCSVLKRQGYGEGFRWMAQYIN 355
>18949
          Length = 414

 Score =  131 bits (330), Expect = 2e-31,   Method: Compositional matrix adjust.
 Identities = 58/87 (66%), Positives = 74/87 (85%)
 Frame = +3

Query: 52  QHVPTLHPTSEELTIAGMTFTTFDLGGHVQARRVWKNYLPAINGIVFLVDCADHERLLES 111
           QH PT  PTSEEL++ GMTFTTFDLGGH QARRVWK+Y PA++GIVF+VD  D ER+ E+
Sbjct: 6   QHRPTGLPTSEELSMGGMTFTTFDLGGHRQARRVWKDYFPAVDGIVFIVDVHDTERITEA 185

Query: 112 KEELDSLMTDETIANVPILILGNKIDR 138
           K ELDSL+ D+ IA++P+L+LGNK+D+
Sbjct: 186 KAELDSLLRDDQIADIPVLVLGNKMDK 266

 Score = 56.2 bits (134), Expect = 9e-09,   Method: Compositional matrix adjust.
 Identities = 30/61 (49%), Positives = 37/61 (60%)
 Frame = +2

Query: 128 PILILGNKIDRPEAISEERLREMFGLYGQTTGKGSVSLKELNARPLEVFMCSVLKRQGYG 187
           P +  G +  +     EE +R   GLY  TTGK   S  EL  RP+E+FMCSV+KRQGYG
Sbjct: 233 PRVGAGQQDGQAWGGGEEDVRHWLGLY-STTGKDKESDSELTGRPVELFMCSVVKRQGYG 409

Query: 188 E 188
           E
Sbjct: 410 E 412
>09827
          Length = 1201

 Score =  100 bits (249), Expect = 4e-22,   Method: Compositional matrix adjust.
 Identities = 51/155 (32%), Positives = 89/155 (57%)
 Frame = -3

Query: 1    MSFIFDWIYSGFSSVLQFLGLYKKSGKLVFLGLDNAGKTTLLHMLKDDRLGQHVPTLHPT 60
            M   F  I+SG S +       KK  +++ +GLD AGKTT+L+ LK   +   +PT+   
Sbjct: 1172 MGNAFQKIFSGLSFMFG-----KKDMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFN 1008

Query: 61   SEELTIAGMTFTTFDLGGHVQARRVWKNYLPAINGIVFLVDCADHERLLESKEELDSLMT 120
             E +    ++FT +D+GG  + R +W++Y     G++F+VD  D ER+ E++EEL  ++ 
Sbjct: 1007 VETVEYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDKERVQEAREELTRMLN 828

Query: 121  DETIANVPILILGNKIDRPEAISEERLREMFGLYG 155
            ++ + +  +L+  NK D P A++   + E  GL+G
Sbjct: 827  EDELRDAVLLVFANKQDLPHAMATAEITEKLGLHG 723
>08153
          Length = 1703

 Score = 96.3 bits (238), Expect = 7e-21,   Method: Compositional matrix adjust.
 Identities = 50/143 (34%), Positives = 83/143 (58%)
 Frame = +1

Query: 11  GFSSVLQFLGLYKKSGKLVFLGLDNAGKTTLLHMLKDDRLGQHVPTLHPTSEELTIAGMT 70
           GF S+ + L   KK  +++ +GLD AGKTT+L+ LK   +   +PT+    E +    ++
Sbjct: 43  GFVSLFKNL-FGKKEVRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNIS 219

Query: 71  FTTFDLGGHVQARRVWKNYLPAINGIVFLVDCADHERLLESKEELDSLMTDETIANVPIL 130
           FT +D+GG  + R +W++Y     G++F+VD  D ER+ E+KEEL  ++ ++ + +  IL
Sbjct: 220 FTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERINEAKEELARMLNEDDLRDAIIL 399

Query: 131 ILGNKIDRPEAISEERLREMFGL 153
           +  NK D P A S   +    GL
Sbjct: 400 VFANKQDLPNAYSASEVTAHLGL 468
>10862
          Length = 2896

 Score = 72.4 bits (176), Expect(2) = 5e-17,   Method: Compositional matrix adjust.
 Identities = 30/83 (36%), Positives = 52/83 (62%)
 Frame = -3

Query: 71   FTTFDLGGHVQARRVWKNYLPAINGIVFLVDCADHERLLESKEELDSLMTDETIANVPIL 130
            F  +D+GG  + R +W++Y     G++F+VDCAD +R+ E+++EL  ++ D  + +  IL
Sbjct: 2480 FNVWDVGGQDKIRPLWRHYYTGTQGLIFVVDCADRDRIDEARQELHRIINDREMRDAIIL 2301

Query: 131  ILGNKIDRPEAISEERLREMFGL 153
            I  NK D P+A+    ++E  GL
Sbjct: 2300 IFANKQDLPDAMKPHEIQEKLGL 2232

 Score = 31.2 bits (69), Expect(2) = 5e-17,   Method: Compositional matrix adjust.
 Identities = 20/37 (54%), Positives = 25/37 (67%)
 Frame = -1

Query: 24   KSGKLVFLGLDNAGKTTLLHMLKDDRLGQHVPTLHPT 60
            K  +++ LGLD AGKTTLL+ +K   LGQ V T  PT
Sbjct: 2620 KEMRILMLGLDAAGKTTLLYKMK---LGQSV-TXIPT 2522
>33605
          Length = 888

 Score = 69.7 bits (169), Expect = 7e-13,   Method: Compositional matrix adjust.
 Identities = 35/104 (33%), Positives = 57/104 (54%)
 Frame = +1

Query: 11  GFSSVLQFLGLYKKSGKLVFLGLDNAGKTTLLHMLKDDRLGQHVPTLHPTSEELTIAGMT 70
           G  ++L+ +   +K  +L+ LGLDNAGKTT+L     + +    PTL    + L   G  
Sbjct: 454 GLLTILKKMKQKEKEVRLLMLGLDNAGKTTILKKFNGEDIDTISPTLGFNIKTLEHRGFK 633

Query: 71  FTTFDLGGHVQARRVWKNYLPAINGIVFLVDCADHERLLESKEE 114
              +D+GG    R  W+NY  + +G+V++VD AD  R+ + K +
Sbjct: 634 LNVWDVGGQQSLRSYWRNYFESTDGLVWVVDSADRMRIADCKRD 765
>18208
          Length = 458

 Score = 60.8 bits (146), Expect = 4e-10,   Method: Compositional matrix adjust.
 Identities = 28/85 (32%), Positives = 47/85 (55%)
 Frame = -1

Query: 27  KLVFLGLDNAGKTTLLHMLKDDRLGQHVPTLHPTSEELTIAGMTFTTFDLGGHVQARRVW 86
           +++ LGLDNAGKTTLL  L  +      PT     + +   G     +D+GG  + R  W
Sbjct: 296 RILLLGLDNAGKTTLLKQLASEDPSHITPTQGFNIKSVQSKGFKLNVWDIGGQRRIRPYW 117

Query: 87  KNYLPAINGIVFLVDCADHERLLES 111
           KNY    + +++++D +D +R+ E+
Sbjct: 116 KNYFENTDLLIYVIDSSDTKRMEET 42
>15973
          Length = 493

 Score = 55.5 bits (132), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 30/108 (27%), Positives = 53/108 (49%)
 Frame = -1

Query: 89  YLPAINGIVFLVDCADHERLLESKEELDSLMTDETIANVPILILGNKIDRPEAISEERLR 148
           Y   +N IV++VD AD ++L  S+ EL +L+    +  VP+L+LGNK D P A+ E+ L 
Sbjct: 487 YCRGVNAIVYMVDAADQDKLEASRNELHNLLDKPQLQGVPVLVLGNKRDLPGALDEKELI 308

Query: 149 EMFGLYGQTTGKGSVSLKELNARPLEVFMCSVLKRQGYGEGFRWMAQY 196
           +   L              +  R +  +  S  +++      +W+ Q+
Sbjct: 307 DRMNLSA------------IQDREICCYSISCKEKENIDITLQWLIQH 200
>11965
          Length = 3256

 Score = 37.7 bits (86), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 32/150 (21%), Positives = 62/150 (41%), Gaps = 12/150 (8%)
 Frame = +1

Query: 25  SGKLVFLGLDNAGKTTLLHMLKDDRLGQHVPTLHPTSEELTIAGMTFTTFDLGGHVQARR 84
           S K     LD  G    +   + D L   V T        +   + F  FD+GG    R+
Sbjct: 55  SAKYFLDDLDRLGTKDYMPT-EQDILRTRVKTTGIVEVHFSFKNLNFKLFDVGGQRSERK 231

Query: 85  VWKNYLPAINGIVFLVDCADHERLLESKEE----------LDSLMTDETIANVPILILGN 134
            W +    +  I+F V  ++++++L   E            DS+  ++   +  I++  N
Sbjct: 232 KWIHCFEDVTAIIFCVAMSEYDQVLHEDETTNRMQESLKLFDSICNNKWFTDTSIILFLN 411

Query: 135 KIDRPEAISEERLRE--MFGLYGQTTGKGS 162
           K D    + EE++++  +   + + TGK +
Sbjct: 412 KKD----LFEEKIKKSPLTVCFPEYTGKQT 489
>32860
          Length = 330

 Score = 37.0 bits (84), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 17/52 (32%), Positives = 26/52 (50%)
 Frame = +2

Query: 86  WKNYLPAINGIVFLVDCADHERLLESKEELDSLMTDETIANVPILILGNKID 137
           W  Y      I+ ++D  D ERL  +KEEL  ++  E +    +L+  NK D
Sbjct: 8   WNTYYSNSEFIIMVIDSTDRERLSITKEELCRMLATEELRXAALLVFANKQD 163
>36734
          Length = 170

 Score = 35.0 bits (79), Expect = 0.022,   Method: Composition-based stats.
 Identities = 12/14 (85%), Positives = 14/14 (100%)
 Frame = -3

Query: 184 QGYGEGFRWMAQYI 197
           QGYGEGFRW+A+YI
Sbjct: 144 QGYGEGFRWLARYI 103
>19006
          Length = 568

 Score = 33.1 bits (74), Expect = 0.081,   Method: Compositional matrix adjust.
 Identities = 35/124 (28%), Positives = 56/124 (45%), Gaps = 6/124 (4%)
 Frame = -2

Query: 20  GLYKKSGKLVFLGLDNAGKTTLLHMLKDDRLGQ-HVPTL---HPTSEELTIAGMTFTTFD 75
           G +K+  KLV +G    GKT LL +   D+  + +VPT+   +    E+    +    +D
Sbjct: 447 GCHKE--KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDSKQVELALWD 274

Query: 76  LGGHVQARRVWKNYLPAINGIV--FLVDCADHERLLESKEELDSLMTDETIANVPILILG 133
             G     R+     P  + I+  F +D  D    LE+  E  +        NVPI+++G
Sbjct: 273 TAGQEDYDRLRPLSYPDTDVILMCFSIDSPDS---LENIPEKWTPEVRHFCPNVPIILVG 103

Query: 134 NKID 137
           NK D
Sbjct: 102 NKKD 91
>19506
          Length = 421

 Score = 32.7 bits (73), Expect = 0.088,   Method: Compositional matrix adjust.
 Identities = 17/42 (40%), Positives = 25/42 (59%)
 Frame = -3

Query: 23  KKSGKLVFLGLDNAGKTTLLHMLKDDRLGQHVPTLHPTSEEL 64
           +K   +++ GLD AGKTTLL+ LK   +   +PT+    E L
Sbjct: 143 QKPVTVIYFGLDAAGKTTLLYNLKLGEVVTTIPTIGFNVETL 18
>29196
          Length = 431

 Score = 32.7 bits (73), Expect = 0.11,   Method: Compositional matrix adjust.
 Identities = 12/48 (25%), Positives = 25/48 (52%)
 Frame = -2

Query: 66  IAGMTFTTFDLGGHVQARRVWKNYLPAINGIVFLVDCADHERLLESKE 113
           +  + F  FD+GG    R+ W +    +  I+F V  ++++++L   E
Sbjct: 232 LKNLNFKLFDVGGQRSERKKWIHCFEDVTAIIFCVAMSEYDQVLHEDE 89
>26083
          Length = 432

 Score = 30.0 bits (66), Expect = 0.58,   Method: Compositional matrix adjust.
 Identities = 29/114 (25%), Positives = 55/114 (48%), Gaps = 5/114 (4%)
 Frame = +1

Query: 27  KLVFLGLDNAGKTTLL-HMLKD--DRLGQHVPTLHPTSEELTIAGMT--FTTFDLGGHVQ 81
           KLVFLG  + GKT+L+   + D  D   Q    +   S+ + +   T     +D  G  +
Sbjct: 82  KLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTIRLQLWDTAGQER 261

Query: 82  ARRVWKNYLPAINGIVFLVDCADHERLLESKEELDSLMTDETIANVPILILGNK 135
            R +  +Y+   +  V + D  +     ++ + +D + T E  ++V I+++GNK
Sbjct: 262 FRSLIPSYIRDSSVAVVVYDITNANSFHQTSKWIDDVRT-ERGSDVIIMLVGNK 420
>22530
          Length = 1070

 Score = 28.9 bits (63), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 14/33 (42%), Positives = 17/33 (51%)
 Frame = +2

Query: 47  DDRLGQHVPTLHPTSEELTIAGMTFTTFDLGGH 79
           D  LG H+P   P  EE+ +A    T FDL  H
Sbjct: 743 DGFLGPHLPLKEPKWEEIPLANTHGTVFDLNFH 841
>03745
          Length = 1266

 Score = 28.1 bits (61), Expect = 2.5,   Method: Compositional matrix adjust.
 Identities = 15/36 (41%), Positives = 19/36 (52%), Gaps = 2/36 (5%)
 Frame = -1

Query: 75  DLGGHVQARRVWKNYLPAINGI--VFLVDCADHERL 108
           D  G  + RR W +YLP    +  VFL+ CA H  L
Sbjct: 633 DFAGVGRHRRSWLHYLPFFITVRRVFLLXCAPHNVL 526
>27645
          Length = 823

 Score = 26.9 bits (58), Expect = 5.8,   Method: Compositional matrix adjust.
 Identities = 8/19 (42%), Positives = 14/19 (73%)
 Frame = -2

Query: 75  DLGGHVQARRVWKNYLPAI 93
           D GGH Q  ++W+N++ A+
Sbjct: 264 DTGGHFQVYKIWRNFIFAL 208
>06379
          Length = 1672

 Score = 26.6 bits (57), Expect = 6.8,   Method: Compositional matrix adjust.
 Identities = 22/77 (28%), Positives = 32/77 (41%), Gaps = 13/77 (16%)
 Frame = -3

Query: 134  NKIDRP-------------EAISEERLREMFGLYGQTTGKGSVSLKELNARPLEVFMCSV 180
            NK D+P             E   E+  R + GL+G+T  K + + K+L      VF+C+ 
Sbjct: 1262 NKSDKPKGPKVTDKVYFDIEIGGEKAGRIVIGLFGKTVPKTAENFKQLCIGDQVVFVCA- 1086

Query: 181  LKRQGYGEGFRWMAQYI 197
                   E  RW   YI
Sbjct: 1085 -------EK*RWQRAYI 1056
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31542273|ref|NP_666269.2| hypothetical protein
LOC230866 isoform 1 [Mus musculus]
         (997 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

04152                                                                 307   2e-83
06842                                                                 168   8e-42
18670                                                                 125   1e-28
23552                                                                  56   8e-08
15812                                                                  32   1.5  
>04152
          Length = 1554

 Score =  307 bits (786), Expect = 2e-83,   Method: Compositional matrix adjust.
 Identities = 176/455 (38%), Positives = 260/455 (57%), Gaps = 30/455 (6%)
 Frame = +1

Query: 404 EQLYIQVFLKKDDS-VGYRALVQTQDHLQLFLQQLAGKVVLWSREESLAEVVCLEMVDLP 462
           E+++  +F KK D  +G + ++ TQD+  L     AGK   W REE+LA +V +EMVDLP
Sbjct: 193 EKIFPMLFTKKKDGRLGAKVMMLTQDY-ALHCTHKAGKAP-WRREEALAYIVAVEMVDLP 366

Query: 463 LTGAQAELEGEFGKKAAIQDGLLGMFLKRLSSQLILLQAWTSHLWKMFYDARKPRSQIKN 522
           ++  +A+ E EFG     +D ++ MF+KR+  Q++ LQA+  HL +         S I  
Sbjct: 367 VSENEAKFEDEFGSS---RDDIVAMFVKRIKVQILQLQAFGKHLIQKAMGQHHHHSMISK 537

Query: 523 EINIDT-----------LARDEFNLQKMMVTVTASGKLFGIESSSGTILWKQYLPNVKP- 570
               D            L RD F+L KM+V VT++GK++G+ S +G + W+ + P++ P 
Sbjct: 538 NDAGDVNEDDDDADDDDLVRDSFSLHKMIVAVTSAGKVYGMRSHTGKLAWQHFFPDLAPF 717

Query: 571 ----DSSFKLMVQRTTAHFPHPPQCTLLVKDKETGMSSLFVFNPIFGKWSQVAPPV---L 623
                 +  L VQRTTAHFPH PQC +L   + +G S +F FNP+ G      P     L
Sbjct: 718 AGQGADNLLLFVQRTTAHFPHAPQCAVLGVSRSSGNSLVFTFNPVTGAMLSDTPXNGLDL 897

Query: 624 KRPILQ-SLLLPVMDQDYAKVLLLVDDEYKVTAFPATRNVLRQLHELAPSIFFYLVDAEQ 682
              ++Q  L+    D+++ K L+L+D + KV  FP +     Q  +    +F +L D + 
Sbjct: 898 GYKVVQVQLMNDNPDENFLKGLILIDSKVKVHFFPPSMKTWVQSQD--SKMFLHLTDPQS 1071

Query: 683 GRLSGYQLR---KDLTTELSWELTIPPEVQRVVKVKGKRSSEHVHSQGRVMGDRSVLYKS 739
           G + GY LR   +++  +  W + +    QRV  V  KR  EH+HSQGRV+GDRSVLYK 
Sbjct: 1072GLMKGYWLRTRDQEVVADNMWNIDLQGGQQRVTGVYTKRPIEHIHSQGRVLGDRSVLYKY 1251

Query: 740 LNPNLLAVVTE------STDVHHERTFIGIFLIDGVTGRIIHSSVQKKARGPVHLVHSEN 793
           LNPN++ +V+E      ST       F  I+L+D VTG I+     K+ RGP+++VHSEN
Sbjct: 1252LNPNMVVIVSEGEEASSSTAAKGPSGFFNIYLVDAVTGHIVFHENHKRTRGPINVVHSEN 1431

Query: 794 WVVYQYWNSKARRNELTALELYEGTEQYNATAFSS 828
           WVVY +++ K RR+E+  LELYEG EQ N+T FSS
Sbjct: 1432WVVYSFYSEKHRRHEMAVLELYEGKEQSNSTHFSS 1536
>06842
          Length = 1587

 Score =  168 bits (426), Expect = 8e-42,   Method: Compositional matrix adjust.
 Identities = 75/136 (55%), Positives = 106/136 (77%)
 Frame = -2

Query: 862  SRHLLIGLPSGAILSLPKALLDPRRPEIPTEQSREENLIPYSPDVQVHAERFINYNQTVS 921
            +R+L+I L  G +LSLPKALLDPRRP IP++++ EE  IPY P++ V  E FINYN+++ 
Sbjct: 1535 TRNLIIALKVGGVLSLPKALLDPRRPSIPSQETMEEGTIPYIPELPVRPEDFINYNRSIF 1356

Query: 922  RMRGIYTAPSGLESTCLVVAYGLDIYQTRVYPSKQFDVLKDDYDYVLISSVLFGLVFATM 981
             +RG++TAP+GLEST LV+ YG+DI+ TRV PSK FDVLKDD+DY+ I+ VL  ++  ++
Sbjct: 1355 NVRGMHTAPAGLESTSLVLVYGIDIFYTRVMPSKMFDVLKDDFDYIFIAGVLAIMIMVSV 1176

Query: 982  ITKRLAQVKLLNRAWR 997
            I+++LA  K L RAW+
Sbjct: 1175 ISQKLAAGKALKRAWK 1128
>18670
          Length = 1273

 Score =  125 bits (313), Expect = 1e-28,   Method: Compositional matrix adjust.
 Identities = 71/207 (34%), Positives = 112/207 (54%), Gaps = 12/207 (5%)
 Frame = -2

Query: 532 DEFNLQKMMVTVTASGKLFGIESSSGTILWKQYLPNVKP-----DSSFKLMVQRTTAHFP 586
           D F+L KM+V VT++GK++G+ S +G + W+ + P++ P       +  L VQRTTAHFP
Sbjct: 726 DSFSLHKMIVAVTSAGKVYGMRSHTGKLAWQHFFPDLAPFAGQGADNLLLFVQRTTAHFP 547

Query: 587 HPPQCTLLVKDKETGMSSLFVFNPIFGKWSQVAPPV---LKRPILQ-SLLLPVMDQDYAK 642
           H PQC +L   + +G S +F FNP+ G      PP    L   ++Q  L+    D+++ K
Sbjct: 546 HAPQCAVLGVSRSSGNSLVFTFNPVTGAMLSDTPPNGLDLGYKVVQVQLMNDNPDENFLK 367

Query: 643 VLLLVDDEYKVTAFPATRNVLRQLHELAPSIFFYLVDAEQGRLSGYQLR---KDLTTELS 699
            L+L+D + KV  FP +     Q  +    +F +L D + G + GY LR   +++  +  
Sbjct: 366 GLILIDSKVKVHFFPPSMKTWVQSQD--SKMFLHLTDPQSGLMKGYWLRTRDQEVVADNM 193

Query: 700 WELTIPPEVQRVVKVKGKRSSEHVHSQ 726
           W + +    QRV  V  KR  EH H+ 
Sbjct: 192 WNIDLRGGQQRVTGVYTKRPIEHTHTH 112
>23552
          Length = 881

 Score = 55.8 bits (133), Expect = 8e-08,   Method: Compositional matrix adjust.
 Identities = 31/73 (42%), Positives = 47/73 (64%), Gaps = 1/73 (1%)
 Frame = -2

Query: 404 EQLYIQVFLKKDDS-VGYRALVQTQDHLQLFLQQLAGKVVLWSREESLAEVVCLEMVDLP 462
           E+++  +F KK D  +G + ++ TQD+  L     AGK   W REE+LA +V +EMVDLP
Sbjct: 691 EKIFPMLFTKKKDGRLGAKVMMLTQDYA-LHCTHKAGKAP-WRREEALAYIVAVEMVDLP 518

Query: 463 LTGAQAELEGEFG 475
           ++  +A+ E EFG
Sbjct: 517 VSENEAKFEDEFG 479
>15812
          Length = 1069

 Score = 31.6 bits (70), Expect = 1.5,   Method: Composition-based stats.
 Identities = 18/43 (41%), Positives = 25/43 (58%)
 Frame = +1

Query: 403 PEQLYIQVFLKKDDSVGYRALVQTQDHLQLFLQQLAGKVVLWS 445
           PE++  QV L  DD + YR +   QDHLQ  LQ+   K+  W+
Sbjct: 22  PERVKSQVRLFADDCLLYRPIHSLQDHLQ--LQEDLKKLETWA 144
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|84043961|ref|NP_938045.2| eukaryotic translation
initiation factor 5B [Mus musculus]
         (1216 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

34603                                                                 139   2e-83
15617                                                                  38   0.020
15991                                                                  35   0.18 
22349                                                                  33   0.69 
33346                                                                  32   1.5  
21954                                                                  30   5.2  
>34603
          Length = 772

 Score =  139 bits (351), Expect(3) = 2e-83,   Method: Compositional matrix adjust.
 Identities = 63/84 (75%), Positives = 78/84 (92%)
 Frame = -3

Query: 975  KGVYVQASTLGSLEALLEFLKTSEVPYAGINIGPVHKKDVMKASVMLEHDPQYAVILAFD 1034
            +GV+VQASTLGSLEALLE+L++ ++ YAGINIGPVHKKD+MKAS+MLEHDPQYAVILAFD
Sbjct: 254  QGVFVQASTLGSLEALLEYLRSEKIKYAGINIGPVHKKDIMKASIMLEHDPQYAVILAFD 75

Query: 1035 VRIERDAQEMADSLGVRIFSAEII 1058
            V ++RD QE+A+S GV IF+A+II
Sbjct: 74   VEVKRDVQELAESSGVTIFTADII 3

 Score =  119 bits (299), Expect(3) = 2e-83,   Method: Composition-based stats.
 Identities = 57/89 (64%), Positives = 74/89 (83%), Gaps = 1/89 (1%)
 Frame = -2

Query: 805 YENKDPRTFVSLVPTSAHTGDGMG-SLIYLLVELTQTMLSKRLAHCEELRAQVMEVKALP 863
           YENK+P+ +VSLVPTSAH+GDGMG   + L+  LTQT+L+KRLA+ EEL+A VMEVKAL 
Sbjct: 771 YENKNPKEYVSLVPTSAHSGDGMG*PWVGLICSLTQTLLAKRLAYSEELQATVMEVKALQ 592

Query: 864 GMGTTIDVILINGRLKEGDTIIVPGVEGP 892
           GMGTTIDVIL+NG++ E  T+++ G +GP
Sbjct: 591 GMGTTIDVILVNGKVCESQTMVLAGTDGP 505

 Score = 91.7 bits (226), Expect(3) = 2e-83,   Method: Compositional matrix adjust.
 Identities = 49/87 (56%), Positives = 59/87 (67%), Gaps = 1/87 (1%)
 Frame = -1

Query: 891 GPIVTQIRGLLLPPPMKELRVK-NQYEKHKEVEAAQGVKILGKDLEKTLAGLPLLVAYKD 949
            P  T IRGLL+P PMKELRVK N Y   KEV AAQGVKI+ KDLEK+LAGLP+ +A+  
Sbjct: 508 APSSTPIRGLLMPQPMKELRVKTNAYNHQKEVLAAQGVKIIAKDLEKSLAGLPMYIAHDK 329

Query: 950 DEIPVLKDELIHELKQTLNAIKLEEKG 976
           DE+   K E    L   L +IKL ++G
Sbjct: 328 DEVEYFKQEAQRGLDDALQSIKLSDRG 248
>15617
          Length = 595

 Score = 38.1 bits (87), Expect = 0.020,   Method: Compositional matrix adjust.
 Identities = 40/138 (28%), Positives = 63/138 (45%), Gaps = 19/138 (13%)
 Frame = -3

Query: 615 EHGKNVNTEKLRAPIICVLGHVDTGKTKILDKL---------------RHTHVQ-DGEAG 658
           +HG+  N   +      V+ HVD GK+ + D L               R T  + D +  
Sbjct: 455 DHGQQKNIRNMS-----VIAHVDHGKSTLTDSLVSKAGIIASAKAGETRFTDTRKDEQER 291

Query: 659 GITQQIGATNVPLEAINEQTKMIK-NFDRENVRIPGMLI--IDTPGHESFSNLRNRGSSL 715
            IT +  A ++  E   +  K IK ++D++N      LI  ID+PGH  FS+       +
Sbjct: 290 CITIKSTAISLYYELKKDDMKYIKQDYDQDN---NAFLINLIDSPGHVDFSSEVTAALRV 120

Query: 716 CDIAILVVDIMHGLEPQT 733
            D A++VVD + G+  QT
Sbjct: 119 TDGALVVVDCVSGVCVQT 66
>15991
          Length = 1629

 Score = 35.0 bits (79), Expect = 0.18,   Method: Compositional matrix adjust.
 Identities = 40/140 (28%), Positives = 52/140 (37%), Gaps = 8/140 (5%)
 Frame = -3

Query: 696  IIDTPGHESFSNLRNRGSSLCDIAILVVDIMHG-------LEPQTIESINILKSKKCP-F 747
            IID PGH  F      G+S  D A+LVV    G        + QT E   +  +      
Sbjct: 1411 IIDAPGHRDFIKNMITGTSQADCAVLVVAAGKGEFEAGISKDGQTREHALLAYTLGVKQL 1232

Query: 748  IVALNKIDRLYDWKKSPDSDVAVTLKKQKKNTKDEFEERAKAIIVEFAQQGLNAALFYEN 807
            IVA+NK+D                   +   + D FEE  K +     + G N       
Sbjct: 1231 IVAVNKMD-----------------STEPPYSMDRFEEIKKEVSTYIKKIGYN------- 1124

Query: 808  KDPRTFVSLVPTSAHTGDGM 827
              P T V+ VP S   GD M
Sbjct: 1123 --PNT-VAFVPISGWVGDNM 1073
>22349
          Length = 662

 Score = 33.1 bits (74), Expect = 0.69,   Method: Compositional matrix adjust.
 Identities = 31/115 (26%), Positives = 49/115 (42%), Gaps = 16/115 (13%)
 Frame = -2

Query: 630 ICVLGHVDTGKTKILDKL---------RHTHVQDGEAGGITQQIGATNVPLEAINEQTKM 680
           +  +GHVD GK+ I   L         R     + EA    ++    +  L+  NE+ + 
Sbjct: 484 VVFIGHVDAGKSTIGGHLLYLTGMVDKRTLEKYEREAKEKNRETWYLSWALDTNNEEREK 305

Query: 681 IKN-------FDRENVRIPGMLIIDTPGHESFSNLRNRGSSLCDIAILVVDIMHG 728
            K        F+ E   +    ++D PGH+SF      G+S  D+AILV+    G
Sbjct: 304 GKTVEVGRAFFETE---LKHFTVLDAPGHKSFVPNMICGASQADLAILVISARRG 149
>33346
          Length = 586

 Score = 32.0 bits (71), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 16/37 (43%), Positives = 23/37 (62%)
 Frame = +1

Query: 404 GKLLTKSQREARARAEVTLRHLQAQGVEVPSKDSLPK 440
           GK LT+ Q++ R R    L  ++ QG  VP+KD +PK
Sbjct: 184 GKFLTEKQKQDRMRLNQMLDVIKEQGGNVPNKDEVPK 294
>21954
          Length = 500

 Score = 30.0 bits (66), Expect = 5.2,   Method: Composition-based stats.
 Identities = 16/43 (37%), Positives = 24/43 (55%), Gaps = 5/43 (11%)
 Frame = +2

Query: 718 IAILVVDIMHGLEPQTIES-----INILKSKKCPFIVALNKID 755
           I + V+D++    P T  S      +IL   + PF+VA+NKID
Sbjct: 74  IVVYVMDVVRSACPTTFMSNMLYACSILYKTRLPFLVAINKID 202
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|9790141|ref|NP_062798.1| actin related protein 2/3
complex, subunit 3 [Mus musculus]
         (178 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

04060                                                                 303   2e-83
16265                                                                  28   1.4  
10406                                                                  28   1.4  
05312                                                                  28   2.2  
04237                                                                  27   3.8  
13043                                                                  27   4.8  
16436                                                                  27   6.5  
>04060
          Length = 1550

 Score =  303 bits (777), Expect = 2e-83,   Method: Compositional matrix adjust.
 Identities = 139/177 (78%), Positives = 162/177 (91%)
 Frame = +2

Query: 1   MPAYHSSLMDPDTKLIGNMALLPLRSQFKGPAPRETKDTDIVDEAIYYFKANVFFKNYEI 60
           MPAYHS+  +P  KLIGNMAL+PL++ +KGPAPRET D DI+DEAIYYFKAN+FF+NYEI
Sbjct: 56  MPAYHSAYTNP-PKLIGNMALVPLKTTYKGPAPRETGDADIIDEAIYYFKANIFFRNYEI 232

Query: 61  KNEADRTLIYITLYISECLKKLQKCNSKSQGEKEMYTLGITNFPIPGEPGFPLNAIYAKP 120
           K+EADRTLIYITLYISECLKKLQKC+S++QGEKEMYTLGI+NFPIPGE GFPLNA+YAKP
Sbjct: 233 KSEADRTLIYITLYISECLKKLQKCSSRNQGEKEMYTLGISNFPIPGEAGFPLNAMYAKP 412

Query: 121 ASKQEDEMMRAYLQQLRQETGLRLCEKVFDPQSDKPSKWWTCFVKRQFMNKSLSGPG 177
           A++ ED+ MR+YLQQLRQETG RL +KVFDPQ+DKPSKWW CF KR+FM+KSLS PG
Sbjct: 413 ANRAEDDTMRSYLQQLRQETGNRLMDKVFDPQTDKPSKWWLCFAKRKFMDKSLSAPG 583
>16265
          Length = 1016

 Score = 28.5 bits (62), Expect = 1.4,   Method: Compositional matrix adjust.
 Identities = 34/131 (25%), Positives = 49/131 (37%), Gaps = 10/131 (7%)
 Frame = +3

Query: 57  NYEIKNEADRTLI-YITLYISECLKKLQKCNSKSQGEKEMYTLGITNFPIPGEPGFPLNA 115
           N+   N     +I Y+TL++     +L      SQ       L +T+  +    G PL  
Sbjct: 339 NFRASNSTLPIVIRYLTLFLLSAFSRLTLFLHVSQATSPR-ALSLTDATLSSTVGXPLPX 515

Query: 116 IYAKPASKQEDEMMRAYLQQLRQETGL--RLCEKVFDPQSDKPSKWWTC-------FVKR 166
             +        E+ R   Q L +ET     LC    D  SD  S WW C       ++  
Sbjct: 516 FASX-------EIGRGERQILXRETSFVSNLCX---DRDSDSRSLWW*CCRGTRHWYMLW 665

Query: 167 QFMNKSLSGPG 177
               +SLSG G
Sbjct: 666 HLTIRSLSGCG 698
>10406
          Length = 1211

 Score = 28.5 bits (62), Expect = 1.4,   Method: Compositional matrix adjust.
 Identities = 15/46 (32%), Positives = 27/46 (58%), Gaps = 7/46 (15%)
 Frame = -2

Query: 59  EIKNEADRTLIYITLYISECLKKLQ-KC------NSKSQGEKEMYT 97
           E K E D   +Y+ LY+S C+  ++ +C      +S+ +GE+E+ T
Sbjct: 724 ERKRETDTKCVYVCLYVSVCVSDVKGECVCVRLRDSEGKGERELET 587
>05312
          Length = 1032

 Score = 28.1 bits (61), Expect = 2.2,   Method: Compositional matrix adjust.
 Identities = 10/23 (43%), Positives = 12/23 (52%)
 Frame = -1

Query: 142 LRLCEKVFDPQSDKPSKWWTCFV 164
           LR+C +V    S  P  WW C V
Sbjct: 531 LRICTRVVIATSMCPRLWWVCLV 463
>04237
          Length = 2632

 Score = 27.3 bits (59), Expect = 3.8,   Method: Compositional matrix adjust.
 Identities = 16/46 (34%), Positives = 24/46 (52%), Gaps = 1/46 (2%)
 Frame = -1

Query: 66   RTLIYITLYISECLKKLQKC-NSKSQGEKEMYTLGITNFPIPGEPG 110
            R  IY  LYI++CL  +Q   +     EK+    G+ ++P P  PG
Sbjct: 1162 RH*IYXLLYINKCLSPIQFIRDGIVSVEKKSEN*GVQDYPFPSPPG 1025
>13043
          Length = 1574

 Score = 26.9 bits (58), Expect = 4.8,   Method: Compositional matrix adjust.
 Identities = 19/70 (27%), Positives = 28/70 (40%), Gaps = 3/70 (4%)
 Frame = +1

Query: 95  MYTLGITNFPIPGEPGFPLNAIYAKPASKQEDEMMRAYLQQ---LRQETGLRLCEKVFDP 151
           ++T G    P P  P  P+N              +R+ L +   L   T LRLC ++   
Sbjct: 925 LWTKGTERLPFPLSPSMPVNTS------------LRSSLVETLFLMDSTLLRLCRRMSMR 1068

Query: 152 QSDKPSKWWT 161
            +  P  WWT
Sbjct: 1069STSSP-XWWT 1095
>16436
          Length = 1316

 Score = 26.6 bits (57), Expect = 6.5,   Method: Compositional matrix adjust.
 Identities = 19/52 (36%), Positives = 25/52 (48%), Gaps = 2/52 (3%)
 Frame = +3

Query: 55  FKNYEIKNEADRTLIYI--TLYISECLKKLQKCNSKSQGEKEMYTLGITNFP 104
           F N    +   +T +YI  TL+IS C K   +C S S  E   YT+ I  F 
Sbjct: 885 FLNMSFASWVVQTYLYILKTLFISLCYKLPWQCKSVSMFEN--YTIVINLFA 1034
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|19072792|ref|NP_083848.1| thioredoxin domain
containing 4 [Mus musculus]
         (406 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

18943                                                                 271   3e-83
06936                                                                  81   1e-15
18455                                                                  62   5e-10
03582                                                                  53   3e-07
28335                                                                  51   7e-07
13979                                                                  40   6e-05
11167                                                                  39   0.005
01000                                                                  37   0.018
35861                                                                  37   0.021
07257                                                                  35   0.052
35310                                                                  33   0.15 
30644                                                                  33   0.24 
04510                                                                  28   5.5  
>18943
          Length = 1035

 Score =  271 bits (692), Expect(2) = 3e-83,   Method: Compositional matrix adjust.
 Identities = 130/242 (53%), Positives = 171/242 (70%), Gaps = 3/242 (1%)
 Frame = +2

Query: 58  CRFSQMLH---PIFEEASDVIKEEYPDKNQVVFARVDCDQHSDIAQRYRISKYPTLKLFR 114
           CR   +     P F+EAS  I EE+    +V+FA+VDCD+   IA +YRISKYPTLKLFR
Sbjct: 191 CRLVSLQSDSGPTFDEASRKISEEFTQPGKVLFAKVDCDKEVTIASQYRISKYPTLKLFR 370

Query: 115 NGMMMKREYRGQRSVKALADYIRQQKSNPVHEIQSLDEVTNLDRSKRNIIGYFEQKDSEN 174
           NG M+K+E+RGQRS  ALA +IR++  + V +  +LD++  LD  KR +IGYFE K+S+N
Sbjct: 371 NGQMVKKEFRGQRSADALAAFIREELKDSVVDHNTLDKLEELDTKKRQVIGYFEAKESDN 550

Query: 175 YRVFERVASILHDDCAFLSAFGDLSKPERYNGDNVIYKPPGRSAPDMVYLGSMTNFDVTY 234
           Y+ F RVAS L D+C F +A G +S  ER  GD V ++PP     D+V++G + NFD   
Sbjct: 551 YKTFLRVASSLRDNCIFNTAVGPVSASERTGGDYVAFRPPHTQRQDVVFMGPLNNFDQLL 730

Query: 235 NWIQDKCVPLVREITFENGEELTEEGLPFLILFHMKDDTESLEIFQNEVARQLISEKGTI 294
           +W  DKCVPLVREITFEN EELTEEGLPFLILFH  +DTE LE+F+ EV++ ++SEK  +
Sbjct: 731 SWALDKCVPLVREITFENAEELTEEGLPFLILFHNPEDTELLELFRTEVSKXILSEKNNV 910

Query: 295 NF 296
            F
Sbjct: 911 KF 916

 Score = 56.2 bits (134), Expect(2) = 3e-83,   Method: Compositional matrix adjust.
 Identities = 25/38 (65%), Positives = 30/38 (78%)
 Frame = +3

Query: 295 NFLHADCDKFRHPLLHIQKTPADCPVIAIDSFRHMYVF 332
           NFL AD  +F HPL H+ KT +D PV+AIDSFRHMY+F
Sbjct: 912 NFLVADGSQFTHPLHHLGKTTSDLPVLAIDSFRHMYLF 1025

 Score = 50.8 bits (120), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 20/39 (51%), Positives = 29/39 (74%)
 Frame = +3

Query: 28  TAEIASLDSENIDEILNNADVALVNFYADWCRFSQMLHP 66
             +  +L+++NI+ I++  DV  VNFYADWCRFSQ+L P
Sbjct: 111 AGDAVALNNDNINTIISRNDVVFVNFYADWCRFSQILAP 227
>06936
          Length = 2198

 Score = 80.9 bits (198), Expect = 1e-15,   Method: Compositional matrix adjust.
 Identities = 83/365 (22%), Positives = 159/365 (43%), Gaps = 16/365 (4%)
 Frame = +3

Query: 21  TSIFTPITA-EIASLDSENIDEILNNADVALVNFYADWCRFSQMLHPIFEEASDVIKEEY 79
           +SI   + A ++  L   +    +    + LV F+A WC   + L P +E A+  + +  
Sbjct: 117 SSIVLAVQASDVLDLKKSDFQSTIEKHSLMLVEFFAPWCGHCKKLAPQYELAATALLKND 296

Query: 80  PDKNQVVFARVDCDQHSDIAQRYRISKYPTLKLFRNGMMMKREYRGQRSVKALADYIRQQ 139
           P    V  A+VDC + +D+  +Y +S YPTLK+FR G + K +Y G R    +  Y+ + 
Sbjct: 297 P---PVPLAKVDCTEETDVCSKYGVSGYPTLKVFRGGEVNK-DYDGPRDKDGIVKYMAKM 464

Query: 140 KSNPVHEIQSLDEVTN-LDRSKRNIIGYFEQKDSENYRVFERVASILHDDCAF-LSAFGD 197
                 E++S++E    L R    ++G+F   +S      ++VA    D   F  +   +
Sbjct: 465 AGPTSKELKSVEEYEKFLSRDGSCVVGFFTGANSGMADTLKKVADS-EDGLRFGYTTSSE 641

Query: 198 LSKPERYNGDNVIYKP---PGRSAPDMVYLGSMTNFDVTYNWIQDKCVPLVREITFENGE 254
           + +  +Y  + V+++P     +     V      N      +++++   L    T +N  
Sbjct: 642 VLEKAKYKDEIVLFRPQKMANKFEDTAVKFTGDANSHNIKKFLKEESFGLCALRTMDNAA 821

Query: 255 ELTEEGLPFLILFHMKD---DTESLEIFQN---EVARQLISEKGTINFLHADCDKFRHPL 308
           +  +   P +I F   D   + +    ++N   +V ++L  E   INF  ++ ++F + L
Sbjct: 822 DFKK---PVVIAFFDVDYVKNAKGSNYWRNRVMKVGKKLRDEGLKINFAVSNKNEFDNEL 992

Query: 309 LHIQKTPA----DCPVIAIDSFRHMYVFGDFKDVLIPGKLKQFVFDLHSGKLHREFHHGP 364
           +      A    D P I   + ++     D +  +     +QFV D+  GKL       P
Sbjct: 993 VECGLKEAVDASDKPAICAYNDKNQKFKMDQEFAM--DTFEQFVRDMLDGKLEAYMKSEP 1166

Query: 365 DPTDT 369
            P ++
Sbjct: 1167VPDNS 1181

 Score = 51.2 bits (121), Expect = 7e-07,   Method: Compositional matrix adjust.
 Identities = 32/116 (27%), Positives = 59/116 (50%), Gaps = 2/116 (1%)
 Frame = +3

Query: 38   NIDEILNNADV-ALVNFYADWCRFSQMLHPIFEEASDVIKEEYPDKNQVVFARVDCDQHS 96
            N +E++N+ +   L+ FYA WC   + L P ++E ++ +K E     ++V A++D   + 
Sbjct: 1212 NFEELVNDPEKDVLIEFYAPWCGHCKTLAPKYDELAEKLKNE----PEIVIAKMDATAN- 1376

Query: 97   DIAQRYRISKYPTLKLFRNGMMMK-REYRGQRSVKALADYIRQQKSNPVHEIQSLD 151
            D+   Y +  +PTL     G     ++Y G R V     Y+ ++ +N   E+Q  D
Sbjct: 1377 DVPPPYDVRGFPTLYFAPKGSKSSPKKYEGGREVNDFVKYLAKEATN---ELQGFD 1535
>18455
          Length = 499

 Score = 61.6 bits (148), Expect = 5e-10,   Method: Compositional matrix adjust.
 Identities = 34/106 (32%), Positives = 51/106 (48%), Gaps = 1/106 (0%)
 Frame = +2

Query: 50  LVNFYADWCRFSQMLHPIFEE-ASDVIKEEYPDKNQVVFARVDCDQHSDIAQRYRISKYP 108
            V F+A WC   Q L PI+EE A  +IKE          +++DC Q+  I Q + +  YP
Sbjct: 200 FVKFFAPWCSHCQRLAPIWEELAKALIKEP-----SATISKIDCTQYRSICQDFEVKGYP 364

Query: 109 TLKLFRNGMMMKREYRGQRSVKALADYIRQQKSNPVHEIQSLDEVT 154
           TL    +G  +++ Y G R +  L  Y+ +    P   I   +E T
Sbjct: 365 TLLWIEDGKKIEK-YAGARDMVTLKTYVEKMIGAPSGNIGLQNEAT 499
>03582
          Length = 1967

 Score = 52.8 bits (125), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 30/108 (27%), Positives = 53/108 (49%), Gaps = 1/108 (0%)
 Frame = +3

Query: 31   IASLDSENIDEI-LNNADVALVNFYADWCRFSQMLHPIFEEASDVIKEEYPDKNQVVFAR 89
            +  L  +N  E+ L+      V FYA WC   + L PI++E +D    ++ DK  VV A+
Sbjct: 1131 VKVLVGKNFKEVALDKTKGVFVEFYAPWCGHCKQLAPIWDELAD----KFTDKADVVIAK 1298

Query: 90   VDCDQHSDIAQRYRISKYPTLKLFRNGMMMKREYRGQRSVKALADYIR 137
            +D   +    +  ++  +PTLK F        +Y G+R++ A   ++ 
Sbjct: 1299 MDSTANE--IEEVKVQSFPTLKYFPKDSDEVIDYNGERTLDAFVKFVE 1436

 Score = 50.1 bits (118), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 25/79 (31%), Positives = 40/79 (50%)
 Frame = +2

Query: 34  LDSENIDEILNNADVALVNFYADWCRFSQMLHPIFEEASDVIKEEYPDKNQVVFARVDCD 93
           L ++N D  +   +  LV FYA WC   + L P + +A+  +K+E  D   V  A+VD  
Sbjct: 128 LTTKNFDSFVKENEFVLVEFYAPWCGHCKALAPEYAKAAQTLKDENSD---VKLAKVDAT 298

Query: 94  QHSDIAQRYRISKYPTLKL 112
             + + +   +  YPTLK 
Sbjct: 299 IETSLGENMGVRGYPTLKF 355
>28335
          Length = 601

 Score = 51.2 bits (121), Expect = 7e-07,   Method: Compositional matrix adjust.
 Identities = 33/110 (30%), Positives = 56/110 (50%), Gaps = 5/110 (4%)
 Frame = -2

Query: 38  NIDEILNNADV-ALVNFYADWCRFSQMLHPIFEEASDVIKEEYPDKNQVVFARVDCDQHS 96
             D+I+NN     L+ FYA WC   Q L P + E + ++K+E PD   +V A++D   + 
Sbjct: 525 TFDKIVNNPKKDVLIEFYAPWCGHCQQLEPKYNELATLLKDE-PD---IVXAKIDATAN- 361

Query: 97  DIAQRYRISKYPTL----KLFRNGMMMKREYRGQRSVKALADYIRQQKSN 142
           D    Y +  +P +    K F+      ++Y G R V A+  YI ++ ++
Sbjct: 360 DTPTPYEVKGFPAIYFSPKRFKE---FPKKYEGDREVDAMLKYIAREATS 220
>13979
          Length = 1480

 Score = 40.4 bits (93), Expect(2) = 6e-05,   Method: Compositional matrix adjust.
 Identities = 19/32 (59%), Positives = 24/32 (75%)
 Frame = +2

Query: 371 PGEQDQDVASSPPESSFQKLAPSEYRYTLLRD 402
           P  Q Q + + PPES+F+KLAPS  RYT+LRD
Sbjct: 104 PNGQAQKI-TDPPESTFRKLAPSRNRYTILRD 196

 Score = 23.5 bits (49), Expect(2) = 6e-05,   Method: Compositional matrix adjust.
 Identities = 9/9 (100%), Positives = 9/9 (100%)
 Frame = +1

Query: 353 SGKLHREFH 361
           SGKLHREFH
Sbjct: 1   SGKLHREFH 27
>11167
          Length = 485

 Score = 38.5 bits (88), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 24/71 (33%), Positives = 36/71 (50%), Gaps = 2/71 (2%)
 Frame = -3

Query: 48  VALVNFYADWCRFSQMLHPIFEEASDVIKEEYPDKN--QVVFARVDCDQHSDIAQRYRIS 105
           + +V+F+ DW        P   +  DV+KE   D +   VVF RV  +  +D++QRY I 
Sbjct: 483 LVVVHFWTDWA-------PQCAQMDDVMKELASDMHYVNVVFVRVAAEDLADVSQRYNIV 325

Query: 106 KYPTLKLFRNG 116
             PT  +F  G
Sbjct: 324 AVPTF-IFLKG 295
>01000
          Length = 1541

 Score = 36.6 bits (83), Expect = 0.018,   Method: Compositional matrix adjust.
 Identities = 16/47 (34%), Positives = 28/47 (59%)
 Frame = -1

Query: 90   VDCDQHSDIAQRYRISKYPTLKLFRNGMMMKREYRGQRSVKALADYI 136
            VDC + S+      I  YPTL +F+NG   + +++G RS+  L +++
Sbjct: 1541 VDCTKQSETCNAQSIRGYPTLAVFQNG-KRQEDFKGTRSLDDLQEFV 1404
>35861
          Length = 850

 Score = 36.6 bits (83), Expect = 0.021,   Method: Compositional matrix adjust.
 Identities = 20/60 (33%), Positives = 33/60 (55%), Gaps = 1/60 (1%)
 Frame = +3

Query: 31  IASLDSENIDEI-LNNADVALVNFYADWCRFSQMLHPIFEEASDVIKEEYPDKNQVVFAR 89
           +  L S+N  E+ L+ +    V FYA WC   + L PI++E    + E++ D + VV A+
Sbjct: 576 VKVLVSKNFKEVALDKSKDVFVEFYAPWCGHCKQLVPIWDE----LGEKFQDSDDVVIAK 743
>07257
          Length = 1477

 Score = 35.0 bits (79), Expect = 0.052,   Method: Compositional matrix adjust.
 Identities = 23/93 (24%), Positives = 35/93 (37%)
 Frame = -3

Query: 44   NNADVALVNFYADWCRFSQMLHPIFEEASDVIKEEYPDKNQVVFARVDCDQHSDIAQRYR 103
            + AD  LV FYA WC F     P +    + +   +P   Q+    VD    S++  R+ 
Sbjct: 1304 STADCVLVMFYAPWCHFCANTAPHY----NALARAFP---QLEVLAVDTVHFSNLNARFG 1146

Query: 104  ISKYPTLKLFRNGMMMKREYRGQRSVKALADYI 136
                P + LF       R    +R       +I
Sbjct: 1145 TVAVPNIMLFHQSRSAVRFNHTERDFHTFLQFI 1047
>35310
          Length = 601

 Score = 33.5 bits (75), Expect = 0.15,   Method: Compositional matrix adjust.
 Identities = 18/58 (31%), Positives = 29/58 (50%)
 Frame = +3

Query: 156 LDRSKRNIIGYFEQKDSENYRVFERVASILHDDCAFLSAFGDLSKPERYNGDNVIYKP 213
           LDR   +++GYF+       R F++VA    D     +   DL +   Y+ D V+Y+P
Sbjct: 33  LDRPGTSVVGYFQNVKGYKARTFQKVADTYGDLRFAFTTDPDLMQHAGYSDDVVLYRP 206
>30644
          Length = 845

 Score = 33.1 bits (74), Expect = 0.24,   Method: Compositional matrix adjust.
 Identities = 15/53 (28%), Positives = 30/53 (56%), Gaps = 2/53 (3%)
 Frame = -3

Query: 26  PITAEIASLDSEN-IDEILN-NADVALVNFYADWCRFSQMLHPIFEEASDVIK 76
           P   ++  +D+++ + ++L  +   ALV FYA WC + + + P F  A+  +K
Sbjct: 492 PTATDVVHIDTDDGLTKLLKKDKSAALVMFYAPWCGYCKRMKPDFAAAATEVK 334

 Score = 31.6 bits (70), Expect = 0.68,   Method: Compositional matrix adjust.
 Identities = 13/30 (43%), Positives = 17/30 (56%)
 Frame = -1

Query: 29  AEIASLDSENIDEILNNADVALVNFYADWC 58
           +E+A L+  N D+ L      LV FYA WC
Sbjct: 110 SEVAHLEDSNFDDFLKQHPSVLVMFYAPWC 21
>04510
          Length = 685

 Score = 28.5 bits (62), Expect = 5.5,   Method: Compositional matrix adjust.
 Identities = 12/53 (22%), Positives = 24/53 (45%)
 Frame = +2

Query: 28  TAEIASLDSENIDEILNNADVALVNFYADWCRFSQMLHPIFEEASDVIKEEYP 80
            +++  L   +    +    + LV F+A WC   + L P +E A+  + +  P
Sbjct: 347 ASDVLDLKKSDFQSTIEKHSLMLVEFFAPWCGHCKKLAPQYELAATALLKNDP 505
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|126723307|ref|NP_932773.2| hypothetical protein
LOC207375 [Mus musculus]
         (1091 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

01750                                                                 305   4e-83
23948                                                                  68   2e-11
15118                                                                  33   0.93 
00178                                                                  30   6.7  
29193                                                                  29   8.7  
>01750
          Length = 1886

 Score =  305 bits (782), Expect = 4e-83,   Method: Compositional matrix adjust.
 Identities = 166/389 (42%), Positives = 229/389 (58%), Gaps = 20/389 (5%)
 Frame = +2

Query: 595 LPPVAPEVLRVAEHRHRRGLMYPYIYHVLTKGEIKIPVCIEDECNMELPPAALLFRSARQ 654
            P V  E+L +A  RH++GLM+P IY +L++GE+K+PV +EDE   ELP    +FR  RQ
Sbjct: 203 FPTVTTEILNIASDRHKKGLMHPMIYQLLSQGEVKLPVTLEDEVAQELPSYTDVFRPVRQ 382

Query: 655 YVYGVLFSLAETQRKMERLAIRR--RLPMEVPSVILKEWSAYKGKSPQTPELVSALTFRE 712
            +Y VLF+L + +   E     +    P     V +KEW   +  +    + V A    +
Sbjct: 383 SIYSVLFNLNKLKIVHETTYKEKGETPPKRAFDVAVKEWVVQQNSNRPVYKTVVARPV-D 559

Query: 713 WTCPNLKKLWLGKAVEDKNRRMRAFLACMKSDTPSMLNPANVPTHLLLMCCVLRYMVQWP 772
           W  P+++++WLGK+ EDKNRR+RAFL  M SD+  +LN   VP HLLLM CVLRY++Q+ 
Sbjct: 560 WKVPSIERMWLGKSDEDKNRRLRAFLTIMHSDSNLVLNTQYVPQHLLLMVCVLRYIMQY- 736

Query: 773 GGRILHRHELDTFLAQAVSTQLYEPDQLQELKIEKLDARGIQLAALFMSGVDTALFANDA 832
            G++L RHELD FLA  VS+ L++   +Q+LK+  +  RG+QLA+LFMSG++TAL AND 
Sbjct: 737 -GQVLQRHELDAFLAMGVSSLLHDEQTMQDLKLPTIVGRGVQLASLFMSGIETALLANDV 913

Query: 833 CGQPVPWEHCCPWIYFDGKLFQSKLIKAGRERVSLVELCDGQADLASKVEKMRQSILEGV 892
           CG PVP   C PW++FDGKLF  KL+KA     SLV+LCDGQ +   ++E++RQS+LE +
Sbjct: 914 CGAPVPAAMCTPWLFFDGKLFHYKLLKA-NGNTSLVDLCDGQMEQVMRLERLRQSVLENL 1090

Query: 893 NMNHPPPSALL--------------PSPTFVPPMVPSLYPVSLYSRAMGSFP----PPPQ 934
           +++   P                    P    P  P        S  MG  P    P P 
Sbjct: 1091HVDFARPQLPGFYPPYPEPYRPGPGSGPGSYRPSGPGPMYRGRGSGPMGPTPGHAGPRPL 1270

Query: 935 ARSRGFAGLHPIPPQGGKLEIAGMVVGQW 963
            R RG  G  P+  +GG LEIAG VVG W
Sbjct: 1271GRGRGILGSCPLDNRGGHLEIAGTVVGSW 1357
>23948
          Length = 387

 Score = 68.2 bits (165), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 32/77 (41%), Positives = 47/77 (61%)
 Frame = +2

Query: 842 CCPWIYFDGKLFQSKLIKAGRERVSLVELCDGQADLASKVEKMRQSILEGVNMNHPPPSA 901
           C PW++FDGKLF  KL+KA     SLV+LCDGQ +   ++E++RQS+LE ++++      
Sbjct: 89  CTPWLFFDGKLFHYKLLKANXN-TSLVDLCDGQMEQVMRLERLRQSVLENLHVD------ 247

Query: 902 LLPSPTFVPPMVPSLYP 918
                 F  P +P  YP
Sbjct: 248 ------FARPQLPGFYP 280
>15118
          Length = 1074

 Score = 32.7 bits (73), Expect = 0.93,   Method: Composition-based stats.
 Identities = 17/80 (21%), Positives = 38/80 (47%)
 Frame = +1

Query: 690 EWSAYKGKSPQTPELVSALTFREWTCPNLKKLWLGKAVEDKNRRMRAFLACMKSDTPSML 749
           E +++      T   +++L  R+WT   +  +WL   V D    +  F+ C + +  +  
Sbjct: 7   EITSWTASGSTTAHSIASLRHRQWTYHRVATMWLWATVPD----IWTFITCNQENIAA-- 168

Query: 750 NPANVPTHLLLMCCVLRYMV 769
            P+ + +H+ ++C   R M+
Sbjct: 169 -PSVILSHMSVVCVAWRSML 225
>00178
          Length = 944

 Score = 29.6 bits (65), Expect = 6.7,   Method: Compositional matrix adjust.
 Identities = 16/47 (34%), Positives = 23/47 (48%)
 Frame = -3

Query: 595 LPPVAPEVLRVAEHRHRRGLMYPYIYHVLTKGEIKIPVCIEDECNME 641
           LPP  PEVL  +EH++  G  Y Y    +     K  V I+ E  ++
Sbjct: 162 LPPKPPEVLEWSEHKNTDGRSYYYNSRTMESTWEKPQVLIDWEAKVK 22
>29193
          Length = 1321

 Score = 29.3 bits (64), Expect = 8.7,   Method: Compositional matrix adjust.
 Identities = 12/33 (36%), Positives = 18/33 (54%)
 Frame = +1

Query: 436  SPGKPMFSRQVPQKMKYPPPFPMGPNSSLLFSH 468
            +P   + +   P K +YP P P  PN++L  SH
Sbjct: 1171 TPAYRLVTINTPTKQEYP*PSPTSPNTTLKLSH 1269
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|74229034|ref|NP_852658.2| importin 7 [Mus musculus]
         (1038 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

14168                                                                 230   5e-83
20038                                                                 225   8e-79
27325                                                                 139   5e-33
>14168
          Length = 1163

 Score =  230 bits (586), Expect(2) = 5e-83,   Method: Compositional matrix adjust.
 Identities = 108/182 (59%), Positives = 140/182 (76%)
 Frame = -1

Query: 613  NTIDTLLSVVEDHKEITQQLEGICLQVIGTVLQQHVLEFYEEIFSLAHSLTCQQVSPQMW 672
            NT++T+L+V+ED KEI  QLEGI L+VIG +LQQ++++FYEE+ SL +SLTC QVS  MW
Sbjct: 1154 NTMETILNVMEDQKEIILQLEGIVLKVIGIILQQNIMDFYEEVLSLIYSLTCGQVSNHMW 975

Query: 673  QLLPLVFEVFQQDGFDYFTDMMPLLHNYXXXXXXXXXXXXKYLEMIYSMCKKVLTGVAGE 732
            ++ P+++ +F++DG DYFTDMMP LHNY              +EMI+ MCK VL+G  GE
Sbjct: 974  EVFPMIYHMFKKDGIDYFTDMMPALHNYVTVDTDAFLSKTHNMEMIFDMCKTVLSGDVGE 795

Query: 733  DAECHAAKLLEVIILQCKGRGIDQCIPLFVEAALERLTREVKTSELRTMCLQVAIAALYY 792
            DAE HAAKL+EVI+LQC G+ +D  +P FVE AL+RLTREV+TSELRTMCLQV I+ALY 
Sbjct: 794  DAEVHAAKLMEVILLQCSGK-VDLVLPTFVELALQRLTREVQTSELRTMCLQVVISALYS 618

Query: 793  NP 794
             P
Sbjct: 617  RP 612

 Score = 97.8 bits (242), Expect(2) = 5e-83,   Method: Compositional matrix adjust.
 Identities = 45/88 (51%), Positives = 58/88 (65%), Gaps = 1/88 (1%)
 Frame = -3

Query: 794 PHLLLNTLENLRFPNNVEPVTNHFITQWLNDVDCFLGLHDRKMCVLGLCALIDMEQI-PQ 852
           P LLL+TL  +  PN    +   F+ QWL+D DCFLGLHDRK+ VLGLC+L+ M    PQ
Sbjct: 615 PQLLLDTLNAIAMPNVQGSILQQFLKQWLHDADCFLGLHDRKLSVLGLCSLVSMTNTRPQ 436

Query: 853 VLNQVSGQILPAFILLFNGLKRAYACHA 880
            +   +  +LPA ++LF GLKRAYA  A
Sbjct: 435 EVTAAAQDVLPAMLILFQGLKRAYASRA 352
>20038
          Length = 986

 Score =  225 bits (574), Expect(2) = 8e-79,   Method: Compositional matrix adjust.
 Identities = 107/203 (52%), Positives = 145/203 (71%), Gaps = 1/203 (0%)
 Frame = +3

Query: 1   MDPNTIIEALRGTMDPALREAAERQLNEAHKSLNFVSTLLQITMSEQLDLPVRQAGVIYL 60
           MD   ++E LR T+DP  RE AE+QL E HK + F   LLQ+ M++ +D+PVRQAGVIYL
Sbjct: 183 MDVAKLVEILRATLDPNHREEAEKQLTEIHKIIGFGPVLLQVVMADPIDMPVRQAGVIYL 362

Query: 61  KNMITQYWPDREA-TPGDIAPYTIPEEDRHCIRENIVEAIIHSPELIRVQLTTCIHHIIK 119
           KNM+TQ+W ++E   P D  P++I E+DR  IR++ +EAIIH+P+ +RVQL  CI HIIK
Sbjct: 363 KNMVTQFWSEKEVENPADPVPFSIHEQDRKHIRDHSIEAIIHAPDPVRVQLCVCISHIIK 542

Query: 120 HDYPSRWTAIVDKIGFYLQSDNSACWLGILLCLYQLVKNYEYKKPEERSPLVAAMQHFLP 179
            DYP RW    +K+  Y+QSDN A W+G LL +YQLVK YEYK+ EER+ +  AM+  LP
Sbjct: 543 CDYPGRWPDAPEKMALYIQSDNHATWMGALLSIYQLVKVYEYKRSEERNVMDMAMKAMLP 722

Query: 180 VLKDRFIQLLSDQSDQSVLIQKQ 202
           +L  R IQ++ D S+ SVL+Q +
Sbjct: 723 MLYQRIIQMIPDPSELSVLLQNK 791

 Score = 88.2 bits (217), Expect(2) = 8e-79,   Method: Compositional matrix adjust.
 Identities = 38/67 (56%), Positives = 51/67 (76%)
 Frame = +2

Query: 201 KQIFKIFYALVQYTLPLELINQQNLTEWVEILKTVVNRDVPNETLQVEEDDRPELPWWKC 260
           +QI KIFYA  Q  LP E++ ++  T+W+E+L+ +V RDVP ET QVEE++R EL WWK 
Sbjct: 785 EQILKIFYAFTQNYLPQEVVTKEVFTQWMEVLRQIVERDVPQETNQVEEEERSELAWWKV 964

Query: 261 KKWALHI 267
           KKWA+HI
Sbjct: 965 KKWAVHI 985
>27325
          Length = 512

 Score =  139 bits (350), Expect = 5e-33,   Method: Compositional matrix adjust.
 Identities = 65/120 (54%), Positives = 88/120 (73%), Gaps = 1/120 (0%)
 Frame = +3

Query: 1   MDPNTIIEALRGTMDPALREAAERQLNEAHKSLNFVSTLLQITMSEQLDLPVRQAGVIYL 60
           MD   ++E LR T+DP  RE AE+QL E HK + F   LLQ+ M++ +D+PVRQAGVIYL
Sbjct: 129 MDVAKLVEILRATLDPNHREEAEKQLTEIHKIIGFGPVLLQVVMADPIDMPVRQAGVIYL 308

Query: 61  KNMITQYWPDREA-TPGDIAPYTIPEEDRHCIRENIVEAIIHSPELIRVQLTTCIHHIIK 119
           KNM+TQ+W ++E   P D  P++I E+DR  IR++ +EAIIH+P+ +RVQL  CI HIIK
Sbjct: 309 KNMVTQFWSEKEVENPADPVPFSIHEQDRKHIRDHSIEAIIHAPDXVRVQLCVCISHIIK 488
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|18079343|ref|NP_542367.1| histidyl-tRNA
synthetase-like [Mus musculus]
         (505 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

18389                                                                 303   1e-82
12536                                                                  47   3e-12
27582                                                                  31   1.2  
29005                                                                  29   4.1  
38868                                                                  29   5.0  
38424                                                                  28   7.5  
>18389
          Length = 664

 Score =  303 bits (776), Expect = 1e-82,   Method: Compositional matrix adjust.
 Identities = 134/212 (63%), Positives = 172/212 (81%)
 Frame = +2

Query: 76  ILDKIISCFKRHGAKGLDTPAFELKEMLTEKYEDNFGLMYDLKDQGGELLSLRYDLTVPF 135
           +  KII CFKRHGA+ +DTP FELKE LT KY ++  L+YDL DQGGE+ SLRYDLTVPF
Sbjct: 2   VFAKIIQCFKRHGAETIDTPVFELKETLTGKYGEDSKLIYDLADQGGEIASLRYDLTVPF 181

Query: 136 ARYLAMNKLKKMKRYQVGKVWRRESPAIAQGRYREFCQCDFDIAGEFDPMIPDAECLRIM 195
           ARYLAMNK+  +KRY + KV+RR++PA+ +GRYREF QCDFDIAG++DPM+PDAEC++++
Sbjct: 182 ARYLAMNKVTNIKRYHIAKVYRRDNPAMTKGRYREFYQCDFDIAGQYDPMLPDAECVKLV 361

Query: 196 CEILSGLQLGDFLIKVNDRRVVDGIFAVCGVPESKLRTICSSMDKLDKMSWEGVRHEMVA 255
            EI+S L +GDF++KVN RR++DG+FA CGVP+ K R ICS++DKLDK  WE VR EMV 
Sbjct: 362 AEIMSSLNIGDFVVKVNHRRLLDGMFAACGVPDGKFRPICSAVDKLDKSPWEDVRXEMVE 541

Query: 256 KKGLAPEVADRIGDFVQYHGGISLVEDLFKDP 287
           +KGL P  ADRIG++V+  GG  L +DL +DP
Sbjct: 542 EKGLDPAAADRIGEYVRLQGGSELADDLLRDP 637
>12536
          Length = 495

 Score = 47.0 bits (110), Expect(3) = 3e-12,   Method: Compositional matrix adjust.
 Identities = 24/45 (53%), Positives = 32/45 (71%)
 Frame = -1

Query: 460 IPLMVIIGEQERNEGVIKLRSVASREEVTINRESLVAEIQKRLSE 504
           IPL VI+G+ E   G++KLR VA+REE  + RE +V EI+K L E
Sbjct: 381 IPLAVILGQSEIEAGIVKLRKVATREEREVKREDMVEEIRKLLQE 247

 Score = 31.6 bits (70), Expect(3) = 3e-12,   Method: Compositional matrix adjust.
 Identities = 14/18 (77%), Positives = 16/18 (88%)
 Frame = -3

Query: 422 QERLKIIAELWDAGIKAE 439
           +ERLK+ AELWDA IKAE
Sbjct: 493 EERLKLCAELWDADIKAE 440

 Score = 30.0 bits (66), Expect(3) = 3e-12,   Method: Composition-based stats.
 Identities = 11/17 (64%), Positives = 12/17 (70%)
 Frame = -2

Query: 442 YKNNPKLLTQLHYCEKA 458
           YK NPK LTQ  YCE+ 
Sbjct: 434 YKRNPKALTQFQYCERG 384
>27582
          Length = 378

 Score = 30.8 bits (68), Expect = 1.2,   Method: Composition-based stats.
 Identities = 14/25 (56%), Positives = 16/25 (64%)
 Frame = +1

Query: 5   GPLRRRAWAALLGQLLRPPSTVCTR 29
           G L   AW  LL +LL PPS +CTR
Sbjct: 163 GTLFTPAWLFLLARLLCPPSGLCTR 237
>29005
          Length = 449

 Score = 29.3 bits (64), Expect = 4.1,   Method: Composition-based stats.
 Identities = 21/64 (32%), Positives = 27/64 (42%), Gaps = 1/64 (1%)
 Frame = -1

Query: 422 QERLKIIAELWDAGIKAEMLYKNNPKLLT-QLHYCEKADIPLMVIIGEQERNEGVIKLRS 480
           Q  L IIA     G+ A   +K+NP L +  +  C     P     G    N  +I LRS
Sbjct: 224 QMHLPIIAISSSGGLNATNRFKHNPSLFSLPVVACSTLSKPCGRCCGSSAPNISIINLRS 45

Query: 481 VASR 484
           V  R
Sbjct: 44  VECR 33
>38868
          Length = 427

 Score = 28.9 bits (63), Expect = 5.0,   Method: Composition-based stats.
 Identities = 12/20 (60%), Positives = 13/20 (65%)
 Frame = -2

Query: 186 IPDAECLRIMCEILSGLQLG 205
           IPD +CL IMCE   GL  G
Sbjct: 144 IPDPDCLIIMCESCXGLYAG 85
>38424
          Length = 686

 Score = 28.5 bits (62), Expect = 7.5,   Method: Compositional matrix adjust.
 Identities = 14/37 (37%), Positives = 18/37 (48%)
 Frame = -3

Query: 22  PPSTVCTRGCHSQVAKAVLTSEQLKSHQEKPNFVIKV 58
           PP   C   C   VA  +L S QL+ +   P F+I V
Sbjct: 597 PPRAKCVWSCDQSVAPLILHSFQLQDYL*FPLFIISV 487
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|226246667|ref|NP_081263.2| DEAH (Asp-Glu-Ala-His) box
polypeptide 16 [Mus musculus]
         (1044 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

09272                                                                 304   1e-82
12784                                                                 295   2e-82
03659                                                                 219   4e-57
20747                                                                 112   6e-25
27144                                                                  69   2e-24
19545                                                                  91   2e-18
19948                                                                  66   6e-11
18403                                                                  62   1e-09
17966                                                                  37   0.053
>09272
          Length = 890

 Score =  304 bits (778), Expect = 1e-82,   Method: Compositional matrix adjust.
 Identities = 144/263 (54%), Positives = 182/263 (69%)
 Frame = +2

Query: 654 LPSDMQARIFQPTPPGARKVVVATNIAETSLTIEGIIYVLDPGFCKQKSYNPRTGMESLT 713
           LPS+MQ RIF+P PPG+RKVV+ATNIAETSLTI GI YV+DPGF KQ  YN +TGM+ L 
Sbjct: 56  LPSEMQTRIFEPAPPGSRKVVIATNIAETSLTINGIYYVVDPGFVKQNVYNSKTGMDQLI 235

Query: 714 VTPCSKASANQXXXXXXXXXXXKCFRLYTAWAYQHELEETTVPEIQRTSLGNVVLLLKSL 773
           VTP S+A A Q           KC+RLYT  AY+ E+  T VPEIQRT+L + VL LK++
Sbjct: 236 VTPISQAQAKQRAGRAGRTGPGKCYRLYTERAYRDEMLPTNVPEIQRTNLASTVLSLKAM 415

Query: 774 GIHDLMHFDFLDPPPYETXXXXXXXXXXXXXXNHLGELTTSGRKMAELPVDPMLSKMILA 833
           GI+DL+ FDF+D PP +T              +  G LT  GR+MAE P++PMLSKM++ 
Sbjct: 416 GINDLLAFDFMDSPPMQTLISAMEQLHALSALDDEGLLTRLGRRMAEFPLEPMLSKMLIM 595

Query: 834 SEKYSCSEEILTVAAMLSVNNSIFYRPKDKVVHADNARVNFFLPGGDHLVLLNVYTQWAE 893
           S   +CS+EILT+ +MLSV N +FYRPKDK   AD  +  F  P GDHL LL+VY  W  
Sbjct: 596 SVHLACSDEILTIVSMLSVQN-VFYRPKDKQALADQKKAKFHQPEGDHLTLLSVYNSWKN 772

Query: 894 SGYSSQWCYENFVQFRSMRRARD 916
           + +SS WCYENFVQ R+++RA+D
Sbjct: 773 NKFSSPWCYENFVQIRTLKRAQD 841
>12784
          Length = 2199

 Score =  295 bits (755), Expect(2) = 2e-82,   Method: Compositional matrix adjust.
 Identities = 155/332 (46%), Positives = 206/332 (62%), Gaps = 5/332 (1%)
 Frame = -1

Query: 671  RKVVVATNIAETSLTIEGIIYVLDPGFCKQKSYNPRTGMESLTVTPCSKASANQXXXXXX 730
            RKVVV+TNIAETSLTI+G+++V+DPGF KQK YNPR  +ESL VT  SKASA Q      
Sbjct: 2199 RKVVVSTNIAETSLTIDGVVFVIDPGFAKQKVYNPRIRVESLLVTAISKASAQQRAGRAG 2020

Query: 731  XXXXXKCFRLYTAWAYQHELEETTVPEIQRTSLGNVVLLLKSLGIHDLMHFDFLDPPPYE 790
                 KCFRLYT  AY  E++E T PEI R++LG+VVL LK LGI DL+HFDF+DPP  E
Sbjct: 2019 RTRPGKCFRLYTEKAYTQEMQENTYPEILRSNLGSVVLQLKKLGIDDLVHFDFMDPPAPE 1840

Query: 791  TXXXXXXXXXXXXXXNHLGELTTSGRKMAELPVDPMLSKMILASEKYSCSEEILTVAAML 850
            T              +  GELT  G  MAE P+DP L+KM++AS   +CS EIL++ +ML
Sbjct: 1839 TLMRALELLNYLAGLDDDGELTELGSMMAEFPLDPQLAKMVIASCDSNCSNEILSITSML 1660

Query: 851  SVNNSIFYRPKDKVVHADNARVNFFLPGGDHLVLLNVYTQWAESGYSSQWCYENFVQFRS 910
            SV    F RP +    AD A++ F    GDHL LLNVY  + ++    QWCY+NF+ +RS
Sbjct: 1659 SVPQC-FVRPTEAKKAADEAKMRFAHIDGDHLTLLNVYHAFKQNHEDPQWCYDNFINYRS 1483

Query: 911  MRRARDXXXXXXXXXXXXXXXXTSCQGD----YVRVRKAITSGYFYHTARLTRSG-YRTV 965
            ++ A +                +S +      Y+ +R+A+ +G+F   A L R+G Y TV
Sbjct: 1482 LKSADNVRQQLARIMDRFNLRRSSTEFTSRDYYLNIRRALVNGFFMQVAHLERTGHYLTV 1303

Query: 966  KQQQTVFIHPNSSLFEQQPRWLLYHELVLTTK 997
            K  Q V +HP S++ + +P W+LY+E VLTTK
Sbjct: 1302 KDNQVVQLHP-STVLDHKPEWVLYNEFVLTTK 1210

 Score = 30.4 bits (67), Expect(2) = 2e-82,   Method: Compositional matrix adjust.
 Identities = 12/49 (24%), Positives = 28/49 (57%), Gaps = 1/49 (2%)
 Frame = -3

Query: 997  KEFMRQVLEIESSWLLEVAPHYYKAKELEDPHAKKMPKK-VGKTREELG 1044
            + ++R V +I+  WL+++AP YY         A+++ ++ + K +  +G
Sbjct: 1213 QNYIRTVTDIKPEWLVKMAPQYYDMSNFPMCEARRVLERIIAKVQNRMG 1067
>03659
          Length = 1566

 Score =  219 bits (558), Expect = 4e-57,   Method: Compositional matrix adjust.
 Identities = 105/195 (53%), Positives = 137/195 (70%)
 Frame = -1

Query: 381 SGPPLSAQAQQKESIQAVRRSLPVFPFREELLAAIANHQVLIIEGETGSGKTTQIPQYLF 440
            G   S   ++ +SI   R+ LP++  ++ELL A+ ++Q+LI+ GETGSGKTTQI QYL 
Sbjct: 582 GGAKASFGKKETKSILEQRQGLPIYKLKDELLKAVHDNQILIVIGETGSGKTTQITQYLA 403

Query: 441 EEGYTKKGMKIACTQPXXXXXXXXXXXXXXEMGVKLGNEVGYSIRFEDCTSERTVLRYMT 500
           E GYT +G KI CTQP              E G +LG EVGY+IRFEDCTS  T ++YMT
Sbjct: 402 ESGYTTRG-KIGCTQPRRVAAMSVAKRVSEEFGCRLGQEVGYTIRFEDCTSPETKIKYMT 226

Query: 501 DGMLLREFLSEPDLASYSVVMVDEAHERTLHTDILFGLIKDVARFRPELKVLVASATLDT 560
           DGMLLRE L + DL  YS+VM+DEAHERT+HTD+LFGL+K   + RP+LK++V SATLD 
Sbjct: 225 DGMLLRECLIDRDLMQYSIVMLDEAHERTIHTDVLFGLLKQAVKKRPDLKLIVTSATLDA 46

Query: 561 ARFSAFFDDAPVFRI 575
            +FS +F +AP+F I
Sbjct: 45  VKFSQYFFEAPIFTI 1
>20747
          Length = 444

 Score =  112 bits (281), Expect = 6e-25,   Method: Compositional matrix adjust.
 Identities = 59/136 (43%), Positives = 84/136 (61%), Gaps = 5/136 (3%)
 Frame = +1

Query: 429 SGKTTQIPQYLFEEGYTKKGMKIACTQPXXXXXXXXXXXXXXEMGVKLGNEVGYSIRFED 488
           SGKTTQ+PQ+L+E GY  KG  I  T+P              EM +    EV Y IR+E 
Sbjct: 1   SGKTTQVPQFLYEAGYAHKGGMIGVTEPRRVAAISMSQRVAEEMNLT-SREVSYQIRYEG 177

Query: 489 CTSERTVLRYMTDGMLLREFLSEPDLASYSVVMVDEAHERTLHTDILFGLIKDVARFRPE 548
             +  T +++MTDG+LLRE   +  L+ YSV+++DEAHER++ TDIL GL+  +A +R +
Sbjct: 178 NVTPDTHIKFMTDGVLLREIQQDFVLSKYSVIILDEAHERSVFTDILIGLLSRIAPYRIK 357

Query: 549 -----LKVLVASATLD 559
                LK+++ SATLD
Sbjct: 358 KNLSPLKLVIMSATLD 405
>27144
          Length = 1128

 Score = 68.9 bits (167), Expect(3) = 2e-24,   Method: Compositional matrix adjust.
 Identities = 34/75 (45%), Positives = 48/75 (64%), Gaps = 3/75 (4%)
 Frame = -1

Query: 949  GYFYHTARLTRSG-YRTVKQQQTVFIHPNSSLFEQQP--RWLLYHELVLTTKEFMRQVLE 1005
            G F + ARL  SG YRTV+    +F+HP S L    P   WL+++E+V T KE++R V  
Sbjct: 768  GLFANAARLHASGSYRTVRDDHELFLHPTSVLSTHSPLPHWLVFNEVVHTNKEYIRDVTS 589

Query: 1006 IESSWLLEVAPHYYK 1020
            I+  WL E+APH+Y+
Sbjct: 588  IQPEWLCELAPHFYQ 544

 Score = 52.8 bits (125), Expect(3) = 2e-24,   Method: Composition-based stats.
 Identities = 23/89 (25%), Positives = 47/89 (52%)
 Frame = -2

Query: 863  KVVHADNARVNFFLPGGDHLVLLNVYTQWAESGYSSQWCYENFVQFRSMRRARDXXXXXX 922
            K   AD  +  F +  GDH+ L+NV+  + +SG +S+WC ++F+ ++ + RA +      
Sbjct: 1025 KRTTADKEKRKFAVEEGDHISLVNVFNTFIKSGKNSRWCSDHFLNYKGLVRAVEIREQLK 846

Query: 923  XXXXXXXXXXTSCQGDYVRVRKAITSGYF 951
                       SC+ +  ++R+ +T+G+ 
Sbjct: 845  RLLQRFKVPLVSCEDEVDKLRRCVTAGFL 759

 Score = 29.6 bits (65), Expect(3) = 2e-24,   Method: Composition-based stats.
 Identities = 15/29 (51%), Positives = 18/29 (62%)
 Frame = -3

Query: 832  LASEKYSCSEEILTVAAMLSVNNSIFYRP 860
            + S  Y CS+E LTVAAM  + N IF  P
Sbjct: 1114 VVSGDYECSQEALTVAAMTQIQN-IFITP 1031
>19545
          Length = 519

 Score = 90.9 bits (224), Expect = 2e-18,   Method: Composition-based stats.
 Identities = 57/150 (38%), Positives = 76/150 (50%), Gaps = 1/150 (0%)
 Frame = +2

Query: 451 IACTQPXXXXXXXXXXXXXXEMGVKLGNEVGYSIRFEDCTSE-RTVLRYMTDGMLLREFL 509
           I  TQP              E    LGN VGYS+RFE         + Y T G LLR+  
Sbjct: 20  IIVTQPRRISAVSIAERVAEERSEMLGNSVGYSVRFETVMPRPYGAMLYCTVGTLLRKL- 196

Query: 510 SEPDLASYSVVMVDEAHERTLHTDILFGLIKDVARFRPELKVLVASATLDTARFSAFFDD 569
            E  L   S V+VDE HER ++TD L  L++D+ R  P+L+VL+ SAT+DT  F+ +F  
Sbjct: 197 -EGGLRGVSHVIVDEIHERDINTDFLLVLLRDMVRAYPDLRVLLMSATVDTTLFTDYFGS 373

Query: 570 APVFRIPGRRFPVDIFYTKAPEADYLEACV 599
             V  + GR +PV  +        YLE C+
Sbjct: 374 CTVVEVYGRVYPVQEY--------YLEDCI 439
>19948
          Length = 466

 Score = 66.2 bits (160), Expect = 6e-11,   Method: Compositional matrix adjust.
 Identities = 35/101 (34%), Positives = 56/101 (55%)
 Frame = +1

Query: 611 PGDILVFLTGQEEIEAACEMLQDRCRRLGSKIRELLVLPIYANLPSDMQARIFQPTPPGA 670
           PG +L FL G   I      LQ      GS   +  +LP+++ +P + Q ++F+P P G 
Sbjct: 130 PGAVLFFLPGWSLIFMIQRHLQ-MSPEFGSS--KYCILPLHSQIPREEQRKVFEPVPDGV 300

Query: 671 RKVVVATNIAETSLTIEGIIYVLDPGFCKQKSYNPRTGMES 711
            K++++TNIAETS+TI  ++YV+D    K K +     M +
Sbjct: 301 TKIILSTNIAETSVTINDVVYVIDSCKVKMKLFTSHNNMTN 423
>18403
          Length = 434

 Score = 62.4 bits (150), Expect = 1e-09,   Method: Composition-based stats.
 Identities = 37/116 (31%), Positives = 60/116 (51%)
 Frame = +2

Query: 739 RLYTAWAYQHELEETTVPEIQRTSLGNVVLLLKSLGIHDLMHFDFLDPPPYETXXXXXXX 798
           RLY    Y +E E  + PEIQR  L ++VL L S+G+ ++  F F++PP   T       
Sbjct: 2   RLYAESDY-NEFEAYSTPEIQRVPLDSLVLQLISMGLPNVRKFPFIEPPDLSTIENSVRF 178

Query: 799 XXXXXXXNHLGELTTSGRKMAELPVDPMLSKMILASEKYSCSEEILTVAAMLSVNN 854
                       LT  G+ ++ LPVD ++ KM++    +   + IL++AA +SV +
Sbjct: 179 LKEQGALAGDESLTAIGQMLSMLPVDVVIGKMLIMGSIFHMVDPILSIAAAMSVQS 346
>17966
          Length = 424

 Score = 36.6 bits (83), Expect = 0.053,   Method: Composition-based stats.
 Identities = 18/65 (27%), Positives = 31/65 (47%)
 Frame = -1

Query: 784 LDPPPYETXXXXXXXXXXXXXXNHLGELTTSGRKMAELPVDPMLSKMILASEKYSCSEEI 843
           ++PPP +               +   ELT  GR +A +P++P L KMI+    +   + +
Sbjct: 235 VEPPPIDAVVEAEATLRSMHALDSNDELTPLGRILARMPIEPHLGKMIIYGCIFYIGDAM 56

Query: 844 LTVAA 848
            T+AA
Sbjct: 55  CTIAA 41
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|78191777|ref|NP_080378.2| dishevelled associated
activator of morphogenesis 1 [Mus musculus]
         (1077 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

11636                                                                 304   1e-82
06817                                                                 145   1e-34
06790                                                                 114   2e-25
27291                                                                 105   9e-23
35444                                                                  79   1e-14
>11636
          Length = 819

 Score =  304 bits (778), Expect = 1e-82,   Method: Compositional matrix adjust.
 Identities = 143/266 (53%), Positives = 198/266 (74%)
 Frame = +1

Query: 720 EDLPKDMLEQLLKFVPEKSDIDLLEEHKHELDRMAKADRFLFEMSRINHYQQRLQSLYFK 779
           EDLPKDM+EQLLKFVP + +  LL E+  E+D MA+ADRFLFEMS+I HY++RL++LYFK
Sbjct: 1   EDLPKDMVEQLLKFVPTQEESSLLSEYAAEIDNMARADRFLFEMSKITHYEERLKALYFK 180

Query: 780 KKFAERVAEVKPKVEAIRSGSEEVFRSRALKQLLEVVLAFGNYMNKGQRGNAYGFKISSL 839
           KKF ER  + K K+EA+    +EVFRSR LKQLLE+VLA GNYMN+GQRGNA GFK +SL
Sbjct: 181 KKFQERRHDCKQKIEAVHEACKEVFRSRKLKQLLELVLACGNYMNRGQRGNALGFKPTSL 360

Query: 840 NKIADTKSSIDKNITLLHYLITIVENKYPKVLNLSEELRDIPQAAKVNMTELDKEISTLR 899
           NK+ DT+SS+ K +TLLHY++  +E K+  V+ L ++L  + +AAKVN  +L+KEI  L+
Sbjct: 361 NKMLDTRSSVSKQVTLLHYVVETLEKKFADVMKLEDDLPHVREAAKVNFKDLEKEIXALK 540

Query: 900 SGLKAVETELEYQKSQPPQPGDKFVSVVSQFITLASFSFSDVEDLLAEAKELFTKAVKHF 959
            GL+ +E E+++ KS+   P D+FV+V+  F T+AS+SF++VED   E +  +   +K F
Sbjct: 541 KGLQGIEKEVDFFKSKLDNPHDRFVNVMQDFCTVASYSFAEVEDAFTEMRNKYDSVLKAF 720

Query: 960 GEEAGKIQPDEFFGIFDQFLQAVAEA 985
            E++ ++QPD FFG FD FL +  EA
Sbjct: 721 CEDSKQVQPDAFFGCFDSFLSSFGEA 798
>06817
          Length = 2234

 Score =  145 bits (365), Expect = 1e-34,   Method: Compositional matrix adjust.
 Identities = 83/288 (28%), Positives = 158/288 (54%), Gaps = 3/288 (1%)
 Frame = +1

Query: 701 RLKLSNDEIKRAILTMDEQEDLPKDMLEQLLKFVP---EKSDIDLLEEHKHELDRMAKAD 757
           ++ ++NDE+ RAI  +D ++ L  D+++ L   +P   E     + E  +  L+ +   D
Sbjct: 4   KIDMTNDEMARAINGLDLKQ-LSLDLVDILQTILPNEQETKAFKMYERDRRPLEALGDED 180

Query: 758 RFLFEMSRINHYQQRLQSLYFKKKFAERVAEVKPKVEAIRSGSEEVFRSRALKQLLEVVL 817
           +F+  M ++     +L  + F   + + + +++P+V AI + S  +  S+ +K+L+E++L
Sbjct: 181 KFMLHMVKVERLSHKLTIMSFIGNYYDNLHQLQPQVNAIIAASMSLKNSQKVKKLMEIIL 360

Query: 818 AFGNYMNKGQRGNAYGFKISSLNKIADTKSSIDKNITLLHYLITIVENKYPKVLNLSEEL 877
           A GNYMN  +RG  YGFK+ SL+ + DTKS  D+  TL+H+L+  V +K+P++L    EL
Sbjct: 361 AMGNYMNSNKRGAVYGFKLQSLDMLVDTKSG-DRKTTLMHFLVQTVHDKFPELLTFDSEL 537

Query: 878 RDIPQAAKVNMTELDKEISTLRSGLKAVETELEYQKSQPPQPGDKFVSVVSQFITLASFS 937
           R + +AA V+M  +  ++  L  G++  + E   +K     P      ++  F+  A   
Sbjct: 538 RFLDKAALVSMENITTDVHELEKGMELTKKEYAARKDSRDCP-----VILKDFLANAEER 702

Query: 938 FSDVEDLLAEAKELFTKAVKHFGEEAGKIQPDEFFGIFDQFLQAVAEA 985
           F  +   +  A++ +TK V+++GE A  + P  FF    +F+ +  +A
Sbjct: 703 FKKLLVDVKTAQDSYTKVVEYYGENARSVSPANFFAQIVRFVNSFKQA 846
>06790
          Length = 620

 Score =  114 bits (285), Expect = 2e-25,   Method: Compositional matrix adjust.
 Identities = 60/191 (31%), Positives = 114/191 (59%), Gaps = 3/191 (1%)
 Frame = -3

Query: 684 LSVIDGRRAQNCNILLSRLKLSNDEIKRAILTMDEQEDLPKDMLEQLLKFVP---EKSDI 740
           +S+++  R +N  I   +++++N+EI RAI  +D +  L  D+++ L   +P   E    
Sbjct: 576 VSLLEPNRLRNVAITRRKIEMTNEEIVRAINGLDLKR-LSLDIVDILQTVLPNDQETKAF 400

Query: 741 DLLEEHKHELDRMAKADRFLFEMSRINHYQQRLQSLYFKKKFAERVAEVKPKVEAIRSGS 800
            L E  +  ++ +   D+F+ +M ++     +L  + F   + + +  ++P++ AI + S
Sbjct: 399 RLYERDRRPVESLGDEDKFMIQMVKVERLSHKLTIMSFIGNYHDNLHHLQPQINAIIAAS 220

Query: 801 EEVFRSRALKQLLEVVLAFGNYMNKGQRGNAYGFKISSLNKIADTKSSIDKNITLLHYLI 860
             +  S  +K+++E++LA GNYMN  +RG AYGFK+ SL+ + DTKS  DK  TL+H+L+
Sbjct: 219 MSLKNSHKVKKMMEIILALGNYMNSNKRGAAYGFKLQSLDMLVDTKSG-DKKTTLMHFLV 43

Query: 861 TIVENKYPKVL 871
             V++K+P +L
Sbjct: 42  QTVQDKFPDLL 10
>27291
          Length = 435

 Score =  105 bits (262), Expect = 9e-23,   Method: Compositional matrix adjust.
 Identities = 55/135 (40%), Positives = 83/135 (61%), Gaps = 1/135 (0%)
 Frame = -2

Query: 743 LEEHKHELDRMAKADRFLFEMSRINHYQQRLQSLYFKKKFAERVAEVKPKVEAIRSGSEE 802
           L   K + D +A+ ++F   MS I    QRL+S+ F+ +F E V ++KP + +     EE
Sbjct: 413 LAAMKDQYDELAEPEQFAIVMSSIKKVHQRLESMLFQMRFQEMVDDIKPDLVSATEACEE 234

Query: 803 VFRSRALKQLLEVVLAFGNYMNKGQR-GNAYGFKISSLNKIADTKSSIDKNITLLHYLIT 861
           V +S   KQLLE+VL  GNY+N G R   + GF IS L K+ +TKS  D +IT+LH+L  
Sbjct: 233 VMKSERFKQLLELVLLMGNYLNSGSRNAQSIGFDISFLPKLENTKSQ-DGSITMLHFLAQ 57

Query: 862 IVENKYPKVLNLSEE 876
           ++E+K+P +L   +E
Sbjct: 56  VIESKHPDILGFIDE 12
>35444
          Length = 506

 Score = 79.0 bits (193), Expect = 1e-14,   Method: Composition-based stats.
 Identities = 38/73 (52%), Positives = 54/73 (73%), Gaps = 1/73 (1%)
 Frame = -1

Query: 806 SRA-LKQLLEVVLAFGNYMNKGQRGNAYGFKISSLNKIADTKSSIDKNITLLHYLITIVE 864
           SRA  K +LE+VLAFGNY+N  +RG AYGFK+ SL+ + DTKS+ DK  +LLHY++  + 
Sbjct: 419 SRAKFKAVLEIVLAFGNYLNSNKRGPAYGFKLQSLDTLIDTKST-DKRSSLLHYIVATIR 243

Query: 865 NKYPKVLNLSEEL 877
            K+P++L+   EL
Sbjct: 242 AKFPELLSFECEL 204
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|42415473|ref|NP_032939.1| protein phosphatase 3,
catalytic subunit, alpha isoform [Mus musculus]
         (521 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

17953                                                                 214   2e-82
01173                                                                 223   1e-58
08242                                                                 221   5e-58
06264                                                                 219   2e-57
06084                                                                 180   1e-45
19040                                                                 161   6e-40
25536                                                                 123   1e-28
18336                                                                  99   4e-22
36367                                                                  70   3e-12
04295                                                                  44   1e-04
21146                                                                  37   0.021
30980                                                                  33   0.34 
02621                                                                  28   6.2  
08384                                                                  28   7.1  
18640                                                                  28   8.4  
>17953
          Length = 626

 Score =  214 bits (544), Expect(3) = 2e-82,   Method: Compositional matrix adjust.
 Identities = 108/144 (75%), Positives = 115/144 (79%)
 Frame = -3

Query: 331 IRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVTEMLVNVLNICSDDELGSEEDGFDGATAA 390
           I +FNCSPHPYWLPNFMDVFTWSLPFVGEKVTEMLVN+LNICSDDEL +E D    A  A
Sbjct: 483 IIKFNCSPHPYWLPNFMDVFTWSLPFVGEKVTEMLVNILNICSDDELVTEGDD-SAAEVA 307

Query: 391 ARKEVIRNKIRAIGKMARVFSVLREESESVLTLKGLTPTGMLPSGVLSGGKQTLQSATVE 450
           ARKEVIRNKIRAIGKMARVF+VLREESESVL LKGLTP G+LP G LSGGK TL S    
Sbjct: 306 ARKEVIRNKIRAIGKMARVFTVLREESESVLQLKGLTPNGLLPLGALSGGKDTLTS---- 139

Query: 451 AIEADEAIKGFSPQHKITSFEEAK 474
                 A+ GFSP HKI+ FEE K
Sbjct: 138 ------ALSGFSPSHKISGFEEDK 85

 Score =  105 bits (263), Expect(3) = 2e-82,   Method: Compositional matrix adjust.
 Identities = 49/54 (90%), Positives = 51/54 (94%)
 Frame = -2

Query: 269 LQHNNLLSILRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKAAVL 322
           LQ NNLLSI+RAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNK  +L
Sbjct: 625 LQQNNLLSIIRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKVQLL 464

 Score = 25.8 bits (55), Expect(3) = 2e-82,   Method: Compositional matrix adjust.
 Identities = 9/21 (42%), Positives = 16/21 (76%)
 Frame = -2

Query: 475 GLDRINERMPPRRDAMPSDAN 495
             +++NERMPPR+D++ +  N
Sbjct: 82  AWNKMNERMPPRKDSVNNTNN 20
>01173
          Length = 2619

 Score =  223 bits (569), Expect = 1e-58,   Method: Compositional matrix adjust.
 Identities = 111/278 (39%), Positives = 169/278 (60%)
 Frame = -1

Query: 52   KEGRLEESVALRIITEGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANT 111
            K  +L ES    +  +   I   +  LL+++AP+ +CGDIHGQ++DL++LFE GG P  +
Sbjct: 2619 KNVQLTESEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPES 2440

Query: 112  RYLFLGDYVDRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKYS 171
             YLFLGDYVDRG  S+E +  L A KI YP+  FLLRGNHEC  +   + F  ECK +Y+
Sbjct: 2439 NYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYN 2260

Query: 172  ERVYDACMDAFDCLPLAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDIL 231
             +++    D F+CLP+AA+++++  C HGGLSP++ +++ IR++ R  + P  G +CD+L
Sbjct: 2259 IKLWKTFTDCFNCLPIAAIIDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLL 2080

Query: 232  WSDPLEDFGNEKTQEHFTHNTVRGCSYFYSYPAVCDFLQHNNLLSILRAHEAQDAGYRMY 291
            WSDP      +K    +  N  RG S+ +    V  FL  ++L  I RAH+  + GY  +
Sbjct: 2079 WSDP------DKETMGWGEND-RGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFF 1921

Query: 292  RKSQTTGFPSLITIFSAPNYLDVYNNKAAVLKYENNVM 329
             K Q      L+T+FSAPNY   ++N  A++  +  +M
Sbjct: 1920 AKRQ------LVTLFSAPNYCGEFDNAGAMMSVDETLM 1825
>08242
          Length = 3368

 Score =  221 bits (563), Expect = 5e-58,   Method: Compositional matrix adjust.
 Identities = 116/259 (44%), Positives = 161/259 (62%), Gaps = 1/259 (0%)
 Frame = -1

Query: 71   ILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYFSIECV 130
            IL +E N+  +D+PVTVCGDIHGQF+DL +LF+VGG   +T YLF+GD+VDRG++S+E  
Sbjct: 3365 ILVEESNVQRVDSPVTVCGDIHGQFYDLKELFKVGGDVPDTNYLFMGDFVDRGFYSVETF 3186

Query: 131  LYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKY-SERVYDACMDAFDCLPLAA 189
            L L ALK+ YP  + L+RGNHE R +T+ + F  EC  KY S  V+  C + FD L L+A
Sbjct: 3185 LLLLALKVRYPDRITLIRGNHESRQITQVYGFYDECLRKYGSITVWRYCTEIFDYLSLSA 3006

Query: 190  LMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWSDPLEDFGNEKTQEHFT 249
            +++ +  CVHGGLSP I TLD IR +DR +E P  GPMCD+LWSDP ED           
Sbjct: 3005 IIDGKIFCVHGGLSPSIQTLDQIRSIDRKQEVPHDGPMCDLLWSDP-EDMQGWGV----- 2844

Query: 250  HNTVRGCSYFYSYPAVCDFLQHNNLLSILRAHEAQDAGYRMYRKSQTTGFPSLITIFSAP 309
              + RG  Y +    V  F   N +  I RAH+    GY+ +         +++T++SAP
Sbjct: 2843 --SPRGAGYLFGSDVVSQFNAANXIDLICRAHQLVMEGYKWHFNE------TVLTVWSAP 2688

Query: 310  NYLDVYNNKAAVLKYENNV 328
            NY     N AA+L+ + ++
Sbjct: 2687 NYCYRCGNVAAILELDEHL 2631
>06264
          Length = 999

 Score =  219 bits (558), Expect = 2e-57,   Method: Compositional matrix adjust.
 Identities = 107/260 (41%), Positives = 162/260 (62%), Gaps = 1/260 (0%)
 Frame = -3

Query: 71  ILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYFSIECV 130
           I   +  LL+++AP+ +CGDIHGQ++DL++LFE GG P  + YLFLGDYVDRG  S+E +
Sbjct: 964 IFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGRQSLETI 785

Query: 131 LYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYDACMDAFDCLPLAAL 190
             L A KI YP+  FLLRGNHEC  +   + F  ECK +Y+ +++    D F+CLP+AA+
Sbjct: 784 CLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAI 605

Query: 191 MNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWSDP-LEDFGNEKTQEHFT 249
           ++++  C HGGLSP++ +++ IR++ R  + P  G +CD+LWSDP  E  G  ++     
Sbjct: 604 IDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKETMGWGESD---- 437

Query: 250 HNTVRGCSYFYSYPAVCDFLQHNNLLSILRAHEAQDAGYRMYRKSQTTGFPSLITIFSAP 309
               RG S+ +    V  FL  ++L  I RAH+  + GY  + K Q      L+T+FSAP
Sbjct: 436 ----RGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQ------LVTLFSAP 287

Query: 310 NYLDVYNNKAAVLKYENNVM 329
           NY   ++N  A++  +  +M
Sbjct: 286 NYCGEFDNAGAMMSVDETLM 227
>06084
          Length = 1739

 Score =  180 bits (457), Expect = 1e-45,   Method: Compositional matrix adjust.
 Identities = 98/236 (41%), Positives = 138/236 (58%), Gaps = 1/236 (0%)
 Frame = -2

Query: 92   HGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYFSIECVLYLWALKILYPKTLFLLRGNH 151
            HGQF+DLM+LF+ GG   +T Y+F+GD+VDRGYFS+E    L  LK  +P  + LLRGNH
Sbjct: 1738 HGQFYDLMELFKTGGEMPDTNYVFMGDFVDRGYFSLETFTLLLTLKAKWPDKIVLLRGNH 1559

Query: 152  ECRHLTEYFTFKQECKIKYSE-RVYDACMDAFDCLPLAALMNQQFLCVHGGLSPEINTLD 210
            E R +T+ + F  EC+ KY     +  C   FD L +AA++++  LCVHGGLSP+I T+D
Sbjct: 1558 ESRQITQIYGFYDECQTKYGNANAWRYCCRVFDLLTIAAIIDECILCVHGGLSPDIKTID 1379

Query: 211  DIRKLDRFKEPPAYGPMCDILWSDPLEDFGNEKTQEHFTHNTVRGCSYFYSYPAVCDFLQ 270
             IR ++R +E P  G  CD++WSDP ED             + RG  + +      +F+ 
Sbjct: 1378 QIRTIERNQEIPHKGAFCDLVWSDP-EDVDTWAM-------SPRGAGWLFGAKVTAEFVA 1223

Query: 271  HNNLLSILRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKAAVLKYEN 326
             NNL  I RAH+    GY+     +      L+T++SAPNY     N AAVL + +
Sbjct: 1222 SNNLKLICRAHQLVHEGYKYMFDEK------LVTVWSAPNYCYRCGNIAAVLSFTD 1073
>19040
          Length = 452

 Score =  161 bits (407), Expect = 6e-40,   Method: Composition-based stats.
 Identities = 68/140 (48%), Positives = 98/140 (70%)
 Frame = -3

Query: 71  ILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYFSIECV 130
           I  Q+  LL+++AP+ +CGDIHGQ+ DL++LFE GG P    YLFLGDYVDRG  S+E +
Sbjct: 423 IFLQQPILLELEAPLIICGDIHGQYTDLLRLFEYGGFPPAANYLFLGDYVDRGKQSLETI 244

Query: 131 LYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYDACMDAFDCLPLAAL 190
             L A KI YP+  FLLRGNHEC  +   + F  ECK +Y+ +++    D F+CLP+AA+
Sbjct: 243 CLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNVKLWKTFTDCFNCLPVAAI 64

Query: 191 MNQQFLCVHGGLSPEINTLD 210
           ++++  C HGGLSP++  ++
Sbjct: 63  IDEKIFCCHGGLSPDLQGME 4
>25536
          Length = 486

 Score =  123 bits (309), Expect = 1e-28,   Method: Compositional matrix adjust.
 Identities = 56/117 (47%), Positives = 78/117 (66%)
 Frame = +1

Query: 55  RLEESVALRIITEGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYL 114
           +L E+    +  +   IL +E N+ ++  PVTVCGD+HGQF DLM+LF +GG   +T YL
Sbjct: 106 QLSENQVKTLCEKAKEILSKESNVQEVKCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYL 285

Query: 115 FLGDYVDRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKYS 171
           F+GDYVDRGY+S+E V  L ALK+ +   + +LRGNHE R +T+ + F  EC  KY 
Sbjct: 286 FMGDYVDRGYYSVETVSLLVALKVRFRDRITILRGNHESRQITQVYGFYDECLRKYG 456
>18336
          Length = 465

 Score = 99.4 bits (246), Expect(2) = 4e-22,   Method: Compositional matrix adjust.
 Identities = 45/81 (55%), Positives = 56/81 (69%)
 Frame = +2

Query: 87  VCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYFSIECVLYLWALKILYPKTLFL 146
           +CGDIHGQ++DL++LFE GG P  + YLFLGDYVDRG  S+E +  L A KI YP+  FL
Sbjct: 104 ICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFL 283

Query: 147 LRGNHECRHLTEYFTFKQECK 167
           LRGNHEC  +   + F    K
Sbjct: 284 LRGNHECASINRIYGFMMNAK 346

 Score = 23.5 bits (49), Expect(2) = 4e-22,   Method: Compositional matrix adjust.
 Identities = 8/12 (66%), Positives = 10/12 (83%)
 Frame = +3

Query: 196 LCVHGGLSPEIN 207
           LC HGGLSP++ 
Sbjct: 429 LCCHGGLSPDLQ 464

 Score = 34.7 bits (78), Expect = 0.086,   Method: Composition-based stats.
 Identities = 19/69 (27%), Positives = 38/69 (55%), Gaps = 1/69 (1%)
 Frame = +1

Query: 131 LYLWALKILYPKTLFLL-RGNHECRHLTEYFTFKQECKIKYSERVYDACMDAFDCLPLAA 189
           ++ ++L+   P+ LFL  R    C +      +  ECK +Y+ +++    D F+CLP+AA
Sbjct: 235 MFTFSLQN*IPRKLFLTTRKPRMCVYQ*NLRVY-DECKRRYNIKLWKTFTDCFNCLPIAA 411

Query: 190 LMNQQFLCV 198
           +++ +   V
Sbjct: 412 IIDVKIFVV 438
>36367
          Length = 827

 Score = 69.7 bits (169), Expect = 3e-12,   Method: Compositional matrix adjust.
 Identities = 46/147 (31%), Positives = 74/147 (50%), Gaps = 13/147 (8%)
 Frame = +1

Query: 199 HGGL-SPEINTLDDIRKLDR----FKEPPAYGPMC-DILWSDPL-------EDFGNEKTQ 245
           HGG+ SPE      +  +++      +P    PM  +ILWSDP+       E   + K  
Sbjct: 1   HGGIPSPENEGGGHLEAINKIPVPLSDPEVDSPMAWEILWSDPISVDLVSPEVLKDMKEH 180

Query: 246 EHFTHNTVRGCSYFYSYPAVCDFLQHNNLLSILRAHEAQDAGYRMYRKSQTTGFPSLITI 305
             FT N+ RG ++F+S  A+  FL+ N L  ++RAHE Q+ G+++ ++ +      L+T+
Sbjct: 181 HGFTFNSRRGTAHFFSCNALLAFLERNGLSHVIRAHEVQEVGFQVQQQGK------LLTV 342

Query: 306 FSAPNYLDVYNNKAAVLKYENNVMNIR 332
           FS+  Y    N  A VL     +  IR
Sbjct: 343 FSSSRYCGGSNEAACVLADNYKLRMIR 423
>04295
          Length = 748

 Score = 44.3 bits (103), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 22/66 (33%), Positives = 35/66 (53%)
 Frame = -1

Query: 264 AVCDFLQHNNLLSILRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKAAVLK 323
            V  FL  ++L  I RAH+  + GY  + K Q      L+T+FSAPNY   ++N   ++ 
Sbjct: 742 VVSKFLNRHDLDLITRAHQVVEDGYEFFAKRQ------LVTLFSAPNYCGEFDNAGGMMS 581

Query: 324 YENNVM 329
            +  +M
Sbjct: 580 VDETLM 563
>21146
          Length = 408

 Score = 37.0 bits (84), Expect = 0.021,   Method: Composition-based stats.
 Identities = 22/58 (37%), Positives = 27/58 (46%)
 Frame = +3

Query: 225 GPMCDILWSDPLEDFGNEKTQEHFTHNTVRGCSYFYSYPAVCDFLQHNNLLSILRAHE 282
           GPMCD+LWSDP +D G           + RG  Y +       F   N L  I RAH+
Sbjct: 117 GPMCDLLWSDP-DDRGGWGI-------SPRGAGYTFGQDISETFNHSNGLTLISRAHQ 266
>30980
          Length = 765

 Score = 32.7 bits (73), Expect = 0.34,   Method: Compositional matrix adjust.
 Identities = 23/72 (31%), Positives = 37/72 (51%), Gaps = 1/72 (1%)
 Frame = +3

Query: 268 FLQHNNLLSILRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKAAVLKYENN 327
           F   N L  I RAH+    GY            +++TIFSAPNY     N+AA+++ ++ 
Sbjct: 6   FNHSNGLTLISRAHQLVMEGYNWCHDR------NVVTIFSAPNYCYRCGNQAAIMELDDA 167

Query: 328 V-MNIRQFNCSP 338
           +  +  QF+ +P
Sbjct: 168 LKYSFLQFDPAP 203
>02621
          Length = 591

 Score = 28.5 bits (62), Expect = 6.2,   Method: Compositional matrix adjust.
 Identities = 13/32 (40%), Positives = 19/32 (59%)
 Frame = +1

Query: 114 LFLGDYVDRGYFSIECVLYLWALKILYPKTLF 145
           L+  DY+  G FS E  L LWA K++ P+ + 
Sbjct: 235 LYCLDYIRHGIFSGES*LKLWAAKVIIPQNML 330
>08384
          Length = 1033

 Score = 28.5 bits (62), Expect = 7.1,   Method: Compositional matrix adjust.
 Identities = 19/80 (23%), Positives = 32/80 (40%), Gaps = 15/80 (18%)
 Frame = +3

Query: 252 TVRGCSYFYSYPAVCDFLQHNNLLSILRAHEAQDAGYRMYRKSQTTG---------FPSL 302
           T  GC + Y+       + HN    +L+ H  ++   + YR+ Q            FPS+
Sbjct: 687 TATGCQHIYTQTGAHTLISHNQSPLLLKKHTKKEID*KNYRRDQQCNHDIMNNPD*FPSI 866

Query: 303 ------ITIFSAPNYLDVYN 316
                 +T+     YLD+ N
Sbjct: 867 KYKSLHLTVNDYITYLDLRN 926
>18640
          Length = 1450

 Score = 28.1 bits (61), Expect = 8.4,   Method: Compositional matrix adjust.
 Identities = 19/79 (24%), Positives = 35/79 (44%), Gaps = 18/79 (22%)
 Frame = +2

Query: 287  GYRMYRKSQTTGF--PSL------ITIFSAPN----------YLDVYNNKAAVLKYENNV 328
            G+  Y+ ++  G+  PS        T+F+AP           +L ++  K  +LK    +
Sbjct: 1127 GWGRYKAAEGEGWAPPSYAVP*TRWTLFTAPTALSGLWDPFTFLQMHG*KLFILKIRKQL 1306

Query: 329  MNIRQFNCSPHPYWLPNFM 347
            + ++   C  HP WL N +
Sbjct: 1307 VLVKTEGCQRHP*WLHNVL 1363
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6680720|ref|NP_031505.1| ADP-ribosylation factor 4
[Mus musculus]
         (180 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

09827                                                                 300   2e-82
08153                                                                 286   2e-78
10862                                                                 157   4e-60
33605                                                                 104   2e-23
11378                                                                 100   4e-22
18208                                                                  98   2e-21
32860                                                                  84   6e-19
06991                                                                  74   2e-14
19506                                                                  71   2e-13
18949                                                                  65   1e-11
15662                                                                  60   5e-10
11965                                                                  49   1e-06
13750                                                                  48   3e-06
34468                                                                  47   4e-06
14775                                                                  41   3e-04
26536                                                                  38   0.002
33794                                                                  37   0.005
29196                                                                  37   0.006
26083                                                                  36   0.009
08428                                                                  35   0.013
33374                                                                  35   0.014
35581                                                                  35   0.023
07465                                                                  33   0.050
13901                                                                  32   0.11 
33380                                                                  31   0.24 
05468                                                                  29   0.82 
20877                                                                  29   1.0  
22540                                                                  29   1.1  
29881                                                                  28   2.5  
34359                                                                  28   3.1  
11257                                                                  27   3.1  
10691                                                                  27   6.0  
36482                                                                  27   6.1  
05400                                                                  27   6.7  
>09827
          Length = 1201

 Score =  300 bits (768), Expect = 2e-82,   Method: Compositional matrix adjust.
 Identities = 145/180 (80%), Positives = 158/180 (87%), Gaps = 3/180 (1%)
 Frame = -3

Query: 1    MGLTISSLFSRL---FGKKQMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVE 57
            MG     +FS L   FGKK MRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVE
Sbjct: 1172 MGNAFQKIFSGLSFMFGKKDMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVE 993

Query: 58   YKNICFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERIQEGAAVLQKMLLEDELQ 117
            YKNI FTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSND+ER+QE    L +ML EDEL+
Sbjct: 992  YKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDKERVQEAREELTRMLNEDELR 813

Query: 118  DAVLLLFANKQDLPNAMAISEMTDKLGLQSLRNRTWYVQATCATQGTGLYEGLDWLSNEL 177
            DAVLL+FANKQDLP+AMA +E+T+KLGL  LRNRTWY+Q+TCAT G GLYEGLDWLSN+L
Sbjct: 812  DAVLLVFANKQDLPHAMATAEITEKLGLHGLRNRTWYIQSTCATTGDGLYEGLDWLSNQL 633
>08153
          Length = 1703

 Score =  286 bits (733), Expect = 2e-78,   Method: Compositional matrix adjust.
 Identities = 135/174 (77%), Positives = 151/174 (86%)
 Frame = +1

Query: 7   SLFSRLFGKKQMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNICFTVW 66
           SLF  LFGKK++RILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNI FTVW
Sbjct: 52  SLFKNLFGKKEVRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNISFTVW 231

Query: 67  DVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERIQEGAAVLQKMLLEDELQDAVLLLFAN 126
           DVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERI E    L +ML ED+L+DA++L+FAN
Sbjct: 232 DVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERINEAKEELARMLNEDDLRDAIILVFAN 411

Query: 127 KQDLPNAMAISEMTDKLGLQSLRNRTWYVQATCATQGTGLYEGLDWLSNELSKR 180
           KQDLPNA + SE+T  LGL +L+ R WY+QATCAT G G+YEGL+WLS  L  +
Sbjct: 412 KQDLPNAYSASEVTAHLGLANLKGRKWYMQATCATSGDGMYEGLEWLSTTLKHK 573
>10862
          Length = 2896

 Score =  157 bits (398), Expect(2) = 4e-60,   Method: Compositional matrix adjust.
 Identities = 70/113 (61%), Positives = 88/113 (77%)
 Frame = -3

Query: 63   FTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERIQEGAAVLQKMLLEDELQDAVLL 122
            F VWDVGGQDKIRPLWRHY+  TQGLIFVVD  DR+RI E    L +++ + E++DA++L
Sbjct: 2480 FNVWDVGGQDKIRPLWRHYYTGTQGLIFVVDCADRDRIDEARQELHRIINDREMRDAIIL 2301

Query: 123  LFANKQDLPNAMAISEMTDKLGLQSLRNRTWYVQATCATQGTGLYEGLDWLSN 175
            +FANKQDLP+AM   E+ +KLGL  LR+R WYVQ +CAT G GL EGL WL++
Sbjct: 2300 IFANKQDLPDAMKPHEIQEKLGLTRLRDRNWYVQPSCATTGDGLCEGLTWLTS 2142

 Score = 90.5 bits (223), Expect(2) = 4e-60,   Method: Compositional matrix adjust.
 Identities = 40/59 (67%), Positives = 52/59 (88%)
 Frame = -1

Query: 3    LTISSLFSRLFGKKQMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNI 61
            +T+  L S++FG K+MRILM+GLDAAGKTT+LYK+KLG+ VT IPT+GFNVETV +KN+
Sbjct: 2659 ITMGKLLSKIFGNKEMRILMLGLDAAGKTTLLYKMKLGQSVTXIPTVGFNVETVSFKNV 2483
>33605
          Length = 888

 Score =  104 bits (259), Expect = 2e-23,   Method: Compositional matrix adjust.
 Identities = 47/88 (53%), Positives = 66/88 (75%)
 Frame = +1

Query: 15  KKQMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNICFTVWDVGGQDKI 74
           +K++R+LM+GLD AGKTTIL K    +I T  PT+GFN++T+E++     VWDVGGQ  +
Sbjct: 490 EKEVRLLMLGLDNAGKTTILKKFNGEDIDTISPTLGFNIKTLEHRGFKLNVWDVGGQQSL 669

Query: 75  RPLWRHYFQNTQGLIFVVDSNDRERIQE 102
           R  WR+YF++T GL++VVDS DR RI +
Sbjct: 670 RSYWRNYFESTDGLVWVVDSADRMRIAD 753
>11378
          Length = 1688

 Score =  100 bits (248), Expect = 4e-22,   Method: Compositional matrix adjust.
 Identities = 55/174 (31%), Positives = 93/174 (53%), Gaps = 14/174 (8%)
 Frame = +3

Query: 15  KKQMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNICFTVWDVGGQDKI 74
           KK  +++ +GLD AGKTT+L+ LK  ++   +PT+    E +    + FT +D+GG  + 
Sbjct: 315 KKSGKLVFLGLDNAGKTTLLHMLKDDKMAQHVPTLHPTSEELSMGGMRFTTFDLGGHRQA 494

Query: 75  RPLWRHYFQNTQGLIFVVDSNDRERIQEGAAVLQKMLLEDELQDAVLLLFANKQDLPNAM 134
           R +W+ YF    G++F+VD +DRER+ E  A L  ++ ++++ +A +L+  NK D P A 
Sbjct: 495 RRVWKDYFPAVDGIVFLVDVHDRERLVEAKAELDSLMTDEQVANAPILVLGNKIDKPGAA 674

Query: 135 AISEMTDKLGLQSL--------------RNRTWYVQATCATQGTGLYEGLDWLS 174
           +  E+    GL SL              R    ++ +    QG G  EG  W++
Sbjct: 675 SEEEIRHWFGLNSLTTGKGTVARGELPGRPMELFMCSVLKRQGYG--EGFRWMA 830
>18208
          Length = 458

 Score = 98.2 bits (243), Expect = 2e-21,   Method: Compositional matrix adjust.
 Identities = 42/87 (48%), Positives = 65/87 (74%)
 Frame = -1

Query: 16  KQMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNICFTVWDVGGQDKIR 75
           +++RIL++GLD AGKTT+L +L   +     PT GFN+++V+ K     VWD+GGQ +IR
Sbjct: 305 RELRILLLGLDNAGKTTLLKQLASEDPSHITPTQGFNIKSVQSKGFKLNVWDIGGQRRIR 126

Query: 76  PLWRHYFQNTQGLIFVVDSNDRERIQE 102
           P W++YF+NT  LI+V+DS+D +R++E
Sbjct: 125 PYWKNYFENTDLLIYVIDSSDTKRMEE 45
>32860
          Length = 330

 Score = 84.3 bits (207), Expect(2) = 6e-19,   Method: Compositional matrix adjust.
 Identities = 36/89 (40%), Positives = 58/89 (65%)
 Frame = +2

Query: 78  WRHYFQNTQGLIFVVDSNDRERIQEGAAVLQKMLLEDELQDAVLLLFANKQDLPNAMAIS 137
           W  Y+ N++ +I V+DS DRER+      L +ML  +EL+ A LL+FANKQD+   M+ +
Sbjct: 8   WNTYYSNSEFIIMVIDSTDRERLSITKEELCRMLATEELRXAALLVFANKQDIKGCMSAA 187

Query: 138 EMTDKLGLQSLRNRTWYVQATCATQGTGL 166
           E++ +L L S+++  W++QA C   G G+
Sbjct: 188 EISXQLNLTSVKDHVWHIQACCGLTGEGV 274

 Score = 25.8 bits (55), Expect(2) = 6e-19,   Method: Compositional matrix adjust.
 Identities = 7/16 (43%), Positives = 14/16 (87%)
 Frame = +1

Query: 165 GLYEGLDWLSNELSKR 180
           GLY+GL+W+++ + +R
Sbjct: 271 GLYQGLEWITSHIRRR 318
>06991
          Length = 1860

 Score = 74.3 bits (181), Expect = 2e-14,   Method: Compositional matrix adjust.
 Identities = 33/69 (47%), Positives = 50/69 (72%)
 Frame = -2

Query: 111  LLEDELQDAVLLLFANKQDLPNAMAISEMTDKLGLQSLRNRTWYVQATCATQGTGLYEGL 170
            L EDEL+ ++L++FANKQD+  AM ++E+ + LGL  L+NR + +  T A +G GL E +
Sbjct: 1859 LEEDELKKSILMVFANKQDIEGAMTVTEVANSLGLPGLKNRKYQIFKTSAVKGEGLDEAM 1680

Query: 171  DWLSNELSK 179
            +WLSN L+K
Sbjct: 1679 EWLSNSLTK 1653
>19506
          Length = 421

 Score = 71.2 bits (173), Expect = 2e-13,   Method: Compositional matrix adjust.
 Identities = 34/59 (57%), Positives = 44/59 (74%)
 Frame = -3

Query: 3   LTISSLFSRLFGKKQMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNI 61
           L + S    LF +K + ++  GLDAAGKTT+LY LKLGE+VTTIPTIGFNVET++   +
Sbjct: 179 LKMGSALCTLFRQKPVTVIYFGLDAAGKTTLLYNLKLGEVVTTIPTIGFNVETLDMNRV 3
>18949
          Length = 414

 Score = 65.1 bits (157), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 30/83 (36%), Positives = 47/83 (56%)
 Frame = +3

Query: 47  PTIGFNVETVEYKNICFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERIQEGAAV 106
           PT     E +    + FT +D+GG  + R +W+ YF    G++F+VD +D ERI E  A 
Sbjct: 15  PTGLPTSEELSMGGMTFTTFDLGGHRQARRVWKDYFPAVDGIVFIVDVHDTERITEAKAE 194

Query: 107 LQKMLLEDELQDAVLLLFANKQD 129
           L  +L +D++ D  +L+  NK D
Sbjct: 195 LDSLLRDDQIADIPVLVLGNKMD 263
>15662
          Length = 455

 Score = 60.1 bits (144), Expect = 5e-10,   Method: Compositional matrix adjust.
 Identities = 27/76 (35%), Positives = 45/76 (59%)
 Frame = +2

Query: 73  KIRPLWRHYFQNTQGLIFVVDSNDRERIQEGAAVLQKMLLEDELQDAVLLLFANKQDLPN 132
           + R +W+ YF    G++F+VD +DRER  E  A L  ++ ++++ +A +L+  NK D P 
Sbjct: 2   QARRVWKDYFPAVDGIVFLVDVHDRERFVEAKAELDSLMTDEQVANAPILVLGNKIDKPG 181

Query: 133 AMAISEMTDKLGLQSL 148
           A +  E+    GL SL
Sbjct: 182 AASEDEIRHWFGLHSL 229
>11965
          Length = 3256

 Score = 48.9 bits (115), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 36/132 (27%), Positives = 56/132 (42%), Gaps = 18/132 (13%)
 Frame = +1

Query: 44  TTIPTIGFNVETVEYKNICFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRE----- 98
           T + T G       +KN+ F ++DVGGQ   R  W H F++   +IF V  ++ +     
Sbjct: 133 TRVKTTGIVEVHFSFKNLNFKLFDVGGQRSERKKWIHCFEDVTAIIFCVAMSEYDQVLHE 312

Query: 99  -----RIQEGAAVLQKMLLEDELQDAVLLLFANKQDL--------PNAMAISEMTDKLGL 145
                R+QE   +   +       D  ++LF NK+DL        P  +   E T   G 
Sbjct: 313 DETTNRMQESLKLFDSICNNKWFTDTSIILFLNKKDLFEEKIKKSPLTVCFPEYT---GK 483

Query: 146 QSLRNRTWYVQA 157
           Q+      Y+QA
Sbjct: 484 QTYEEVAAYIQA 519
>13750
          Length = 503

 Score = 47.8 bits (112), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 32/114 (28%), Positives = 54/114 (47%), Gaps = 6/114 (5%)
 Frame = -2

Query: 30  KTTILYKLKLGEIV-TTIPTIG-----FNVETVEYKNICFTVWDVGGQDKIRPLWRHYFQ 83
           KT +L + + G  +  T+PTI      FN    +  N+ +T+WD GG +  R LW  +F+
Sbjct: 502 KTCLLRRYQKGFFMDRTMPTIAVLCSEFNESRTDPLNVRYTLWDTGGAETYRSLWVSHFR 323

Query: 84  NTQGLIFVVDSNDRERIQEGAAVLQKMLLEDELQDAVLLLFANKQDLPNAMAIS 137
             Q  + V D            V +K L+++ + +A ++   +K DL     IS
Sbjct: 322 GAQVALLVYDVTCEWSFLTATTVWRKALMKN-IPEAQVIFVGSKTDLEENRVIS 164
>34468
          Length = 1502

 Score = 47.0 bits (110), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 30/129 (23%), Positives = 64/129 (49%), Gaps = 6/129 (4%)
 Frame = +1

Query: 15  KKQMRILMVGLDAAGKTTILYKLKLGEIV-TTIPTIGFNVET----VEYKNICFTVWDVG 69
           ++  +I+++G    GKT + Y+  LG+    T  TIG +       V+ +++   +WD  
Sbjct: 487 RRIFKIIVIGDSNVGKTCLTYRFCLGKFPDKTEATIGVDFREKSIQVDSEHLKLQLWDTA 666

Query: 70  GQDKIR-PLWRHYFQNTQGLIFVVDSNDRERIQEGAAVLQKMLLEDELQDAVLLLFANKQ 128
           GQ++ R  + +HY++N   ++FV D       +   A +++    +  +    +L  NK 
Sbjct: 667 GQERFRKSMVQHYYRNVHAVVFVYDMTKMSSFENMPAWIEECDRHNLTKYIPRILVGNKC 846

Query: 129 DLPNAMAIS 137
           D+   +A++
Sbjct: 847 DVVERIAVN 873
>14775
          Length = 380

 Score = 40.8 bits (94), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 23/70 (32%), Positives = 36/70 (51%), Gaps = 6/70 (8%)
 Frame = -2

Query: 30  KTTILYKLKLGEIV-TTIPTIG-----FNVETVEYKNICFTVWDVGGQDKIRPLWRHYFQ 83
           KT +L + + G  +  T+PTI      FN    +  N+ +T+WD GG +  R LW  +F+
Sbjct: 379 KTCLLRRYQKGFFMDRTMPTIAVLCSEFNESRTDPLNVRYTLWDTGGAETYRSLWVSHFR 200

Query: 84  NTQGLIFVVD 93
             Q  + V D
Sbjct: 199 GAQVALLVYD 170
>26536
          Length = 829

 Score = 38.1 bits (87), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 23/92 (25%), Positives = 41/92 (44%), Gaps = 5/92 (5%)
 Frame = +2

Query: 59  KNICFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERIQEGAAVLQKMLLEDELQD 118
           + + +T  D  GQ++   +  HY ++  G I V    D    QE  AV + +    +   
Sbjct: 122 RRVSWTFLDTAGQEEYSSMREHYTRSGDGFIVVYSVTDVTSFQEAEAVFRWLTRFQDETS 301

Query: 119 AVLLLFANKQDLPNAMAIS-----EMTDKLGL 145
              +L  NK DL +   ++     +M D+LG+
Sbjct: 302 IHAVLCGNKTDLTSDRKVTPEEGRKMADRLGM 397
>33794
          Length = 779

 Score = 36.6 bits (83), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 24/93 (25%), Positives = 42/93 (45%), Gaps = 12/93 (12%)
 Frame = -1

Query: 48  TIGFNVETV--EYKNICFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDR-------- 97
           T+ +   T+  E K +   +WD  GQ +   + R Y +  QG+I V D  ++        
Sbjct: 695 TVAYKTTTILLEGKRVKLQIWDTSGQGRFCTIIRSYSRGAQGIILVYDITNKWSFDGIDR 516

Query: 98  --ERIQEGAAVLQKMLLEDELQDAVLLLFANKQ 128
             + ++E A  + K+L+ + L  A     A KQ
Sbjct: 515 WLKEVEEHAPGIPKVLVGNRLHLAYKRQVAAKQ 417
>29196
          Length = 431

 Score = 36.6 bits (83), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 21/76 (27%), Positives = 35/76 (46%), Gaps = 10/76 (13%)
 Frame = -2

Query: 59  KNICFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRE----------RIQEGAAVLQ 108
           KN+ F ++DVGGQ   R  W H F++   +IF V  ++ +          R+QE   +  
Sbjct: 229 KNLNFKLFDVGGQRSERKKWIHCFEDVTAIIFCVAMSEYDQVLHEDETTNRMQESLKLFD 50

Query: 109 KMLLEDELQDAVLLLF 124
            +       D  ++LF
Sbjct: 49  SICNNKWFTDTSIILF 2
>26083
          Length = 432

 Score = 35.8 bits (81), Expect = 0.009,   Method: Compositional matrix adjust.
 Identities = 24/117 (20%), Positives = 54/117 (46%), Gaps = 5/117 (4%)
 Frame = +1

Query: 16  KQMRILMVGLDAAGKTTILYKLKLGEIVTTI-PTIGFNVET----VEYKNICFTVWDVGG 70
           ++ +++ +G  + GKT+++ +        T   TIG +  +    +E + I   +WD  G
Sbjct: 73  RKFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTIRLQLWDTAG 252

Query: 71  QDKIRPLWRHYFQNTQGLIFVVDSNDRERIQEGAAVLQKMLLEDELQDAVLLLFANK 127
           Q++ R L   Y +++   + V D  +     + +  +  +  E    D +++L  NK
Sbjct: 253 QERFRSLIPSYIRDSSVAVVVYDITNANSFHQTSKWIDDVRTE-RGSDVIIMLVGNK 420
>08428
          Length = 1109

 Score = 35.4 bits (80), Expect = 0.013,   Method: Compositional matrix adjust.
 Identities = 20/83 (24%), Positives = 39/83 (46%), Gaps = 5/83 (6%)
 Frame = -3

Query: 16   KQMRILMVGLDAAGKTTILYKLKLGEI-VTTIPTIGFNVET----VEYKNICFTVWDVGG 70
            + +++ ++G    GK++I+ +   G    +   TIG +  +    V+     F +WD  G
Sbjct: 1074 RDVKVCLLGDSGVGKSSIVLRFVTGSYRPSQESTIGASFMSKSLVVDGAGYRFQIWDTAG 895

Query: 71   QDKIRPLWRHYFQNTQGLIFVVD 93
            Q+K R L   Y++     + V D
Sbjct: 894  QEKFRALAPMYYRGAAAAVIVYD 826
>33374
          Length = 489

 Score = 35.4 bits (80), Expect = 0.014,   Method: Compositional matrix adjust.
 Identities = 21/72 (29%), Positives = 32/72 (44%)
 Frame = +1

Query: 61  ICFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERIQEGAAVLQKMLLEDELQDAV 120
           + F +WD  GQ++   L   Y++  Q  I V D  +++     A    K L      + V
Sbjct: 175 VKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNQDTFGR-AKTWVKELQRQASPNIV 351

Query: 121 LLLFANKQDLPN 132
           + L  NK DL N
Sbjct: 352 IALAGNKADLAN 387
>35581
          Length = 364

 Score = 34.7 bits (78), Expect = 0.023,   Method: Compositional matrix adjust.
 Identities = 20/91 (21%), Positives = 44/91 (48%), Gaps = 6/91 (6%)
 Frame = +2

Query: 18  MRILMVGLDAAGKTTILYKLK----LGEIVTTIPTIGFNVETVEYKNICFTV--WDVGGQ 71
            + +++G    GKT +L +L     L   +T++ T            +  +V  WD  GQ
Sbjct: 47  FKCVLLGDAGVGKTCLLNRLATDKFLDSPLTSLTTASLLTTVTLTSGVMASVDLWDTAGQ 226

Query: 72  DKIRPLWRHYFQNTQGLIFVVDSNDRERIQE 102
           ++ R L   Y+++T+ ++ V D+  + ++ +
Sbjct: 227 ERYRSLTSSYYRDTKAVLIVYDAEHKLKLTD 319
>07465
          Length = 1103

 Score = 33.5 bits (75), Expect = 0.050,   Method: Compositional matrix adjust.
 Identities = 17/72 (23%), Positives = 37/72 (51%)
 Frame = +3

Query: 59  KNICFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERIQEGAAVLQKMLLEDELQD 118
           +++   +WD  GQ++   + + Y++  Q  +    + DR+  +  A    K  +EDE+ +
Sbjct: 339 EDVRLMLWDTAGQEEFDAITKAYYRGAQACVLAFSTVDRDSFE--ALETWKRKVEDEVGE 512

Query: 119 AVLLLFANKQDL 130
             +++  NK DL
Sbjct: 513 IGMVIVQNKIDL 548
>13901
          Length = 962

 Score = 32.3 bits (72), Expect = 0.11,   Method: Compositional matrix adjust.
 Identities = 18/100 (18%), Positives = 43/100 (43%), Gaps = 14/100 (14%)
 Frame = -3

Query: 18  MRILMVGLDAAGKTTIL-----------YKLKLGEIVTTIPTIGFNVETVEYKNIC---F 63
            +++++G    GKT+ +           YK+ +G        + F ++ + + + C    
Sbjct: 285 FKVIIIGDPTVGKTSFVQRYVNDSFRRDYKMTIG--------VDFALKVIRWSDKCNIKL 130

Query: 64  TVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERIQEG 103
            +WD+ GQ++   + R Y+++    I + D   +   Q  
Sbjct: 129 QLWDIAGQERFTSMTRVYYKDAHACIVMFDLTQKNTYQNA 10
>33380
          Length = 282

 Score = 31.2 bits (69), Expect = 0.24,   Method: Compositional matrix adjust.
 Identities = 18/77 (23%), Positives = 36/77 (46%), Gaps = 3/77 (3%)
 Frame = +3

Query: 59  KNICFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRER---IQEGAAVLQKMLLEDE 115
           K +   +WD  GQ++ R +   Y++   G I + D  + E    +Q+    ++    +  
Sbjct: 54  KRVKLQIWDTAGQERYRTITTAYYRGAMGFILMYDVTNEESFNAVQDWCTQIKTYSWD-- 227

Query: 116 LQDAVLLLFANKQDLPN 132
             +A ++L  NK DL +
Sbjct: 228 --NAQVVLVGNKCDLED 272
>05468
          Length = 1558

 Score = 29.3 bits (64), Expect = 0.82,   Method: Compositional matrix adjust.
 Identities = 20/86 (23%), Positives = 41/86 (47%), Gaps = 11/86 (12%)
 Frame = -3

Query: 19   RILMVGLDAAGKTTIL-----------YKLKLGEIVTTIPTIGFNVETVEYKNICFTVWD 67
            +IL++G    GKT+I+           Y+  +G +   +  + ++ +T+    I   +WD
Sbjct: 1535 KILVIGELGTGKTSIIKRYVHQFFSQHYRATIG-VDFALKVLNWDADTL----IRLQLWD 1371

Query: 68   VGGQDKIRPLWRHYFQNTQGLIFVVD 93
            + GQ++   + R Y++   G   V D
Sbjct: 1370 IAGQERFGNMTRVYYKEAVGAFVVFD 1293
>20877
          Length = 381

 Score = 29.3 bits (64), Expect = 1.0,   Method: Compositional matrix adjust.
 Identities = 12/13 (92%), Positives = 13/13 (100%)
 Frame = -1

Query: 165 GLYEGLDWLSNEL 177
           GLYEGLDWLSN+L
Sbjct: 378 GLYEGLDWLSNQL 340
>22540
          Length = 337

 Score = 28.9 bits (63), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 12/14 (85%), Positives = 13/14 (92%)
 Frame = +2

Query: 166 LYEGLDWLSNELSK 179
           LYEGLDWLSNEL+ 
Sbjct: 2   LYEGLDWLSNELAS 43
>29881
          Length = 416

 Score = 27.7 bits (60), Expect = 2.5,   Method: Compositional matrix adjust.
 Identities = 10/29 (34%), Positives = 15/29 (51%)
 Frame = -2

Query: 57  EYKNICFTVWDVGGQDKIRPLWRHYFQNT 85
           E + +CF+VW  G +  +   WRH    T
Sbjct: 403 EGRQLCFSVWCPG*RHHVEEGWRHVHSGT 317
>34359
          Length = 1042

 Score = 27.7 bits (60), Expect = 3.1,   Method: Compositional matrix adjust.
 Identities = 34/153 (22%), Positives = 61/153 (39%), Gaps = 21/153 (13%)
 Frame = +3

Query: 17  QMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKN----ICFTVWDVGGQD 72
             ++++VG        I+ +   G     + T+G  V  +++      + F VWD  GQ+
Sbjct: 51  NFKLVLVGGRWEWANNIVKRHVTGS*KKYVATLGVEVHPLQFNTSRGLLRFNVWDTAGQE 230

Query: 73  KIRPLWR--HYFQNTQGLI-FVVDS-----------NDRERIQEGAAVL---QKMLLEDE 115
           K   L R  +Y Q T  +I F V S            D  R+ E   ++    K+ ++D 
Sbjct: 231 KFGGL-RDGYYIQGTCAIIMFDVTSRVTYKNVPNWHRDLVRVCENIPIVLCGNKVDIKDR 407

Query: 116 LQDAVLLLFANKQDLPNAMAISEMTDKLGLQSL 148
              A  ++F  K+      ++   T  L  +S 
Sbjct: 408 KVKAKAIVFHRKRTCSTTTSVPRATTTLRSRSC 506
>11257
          Length = 1102

 Score = 27.3 bits (59), Expect = 3.1,   Method: Compositional matrix adjust.
 Identities = 20/103 (19%), Positives = 46/103 (44%), Gaps = 10/103 (9%)
 Frame = -2

Query: 46   IPTIGFNVETVEYKNIC-----FT--VWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRE 98
            +P++  +   V +K++      FT  +WD  GQ++ + L   +++ T   +     ++ +
Sbjct: 1092 MPSLPHDRRGVPHKDVVVDGETFTMQIWDTAGQERYKSLRTPFYRGTDCCLLTFSVDNLK 913

Query: 99   RIQEGAAVLQKMLLEDELQDAVLLLF---ANKQDLPNAMAISE 138
             +Q  +    + +   ++QD+    F    NK D+      SE
Sbjct: 912  SLQSLSDWYDEFVNYADIQDSASFPFVIIGNKADIEEREVSSE 784
>10691
          Length = 857

 Score = 26.6 bits (57), Expect = 6.0,   Method: Compositional matrix adjust.
 Identities = 11/34 (32%), Positives = 19/34 (55%)
 Frame = +2

Query: 59  KNICFTVWDVGGQDKIRPLWRHYFQNTQGLIFVV 92
           K+ C  +W V G+D    + ++  +N Q  IFV+
Sbjct: 104 KDFCLELW-VSGKDDFNKIRKYNIRNNQSAIFVI 202
>36482
          Length = 686

 Score = 26.6 bits (57), Expect = 6.1,   Method: Compositional matrix adjust.
 Identities = 29/141 (20%), Positives = 56/141 (39%)
 Frame = +2

Query: 39  LGEIVTTIPTIGFNVETVEYKNICFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRE 98
           +GE   T+ ++      +E  ++   + D  GQ    P    Y       +FV   NDR+
Sbjct: 32  IGEYCPTLESVYKYHTVIEDDDVRLEILDTAGQGTY-PWKEGYALWADCFVFVYSINDRQ 208

Query: 99  RIQEGAAVLQKMLLEDELQDAVLLLFANKQDLPNAMAISEMTDKLGLQSLRNRTWYVQAT 158
             +E   V +++    +      +L ANK DL +   +++   +   + +  R + V A+
Sbjct: 209 SYEELVQVKRQVESVRKSTSLTAVLAANKTDLLHDRQVTQKEGEDLAEEIGCRLYEVSAS 388

Query: 159 CATQGTGLYEGLDWLSNELSK 179
             +Q   +      L  E  K
Sbjct: 389 EGSQMEAITSMFHDLYREFRK 451
>05400
          Length = 1916

 Score = 26.6 bits (57), Expect = 6.7,   Method: Compositional matrix adjust.
 Identities = 11/22 (50%), Positives = 13/22 (59%)
 Frame = -3

Query: 60   NICFTVWDVGGQDKIRPLWRHY 81
            N+CF VW   GQ     LWRH+
Sbjct: 1155 NVCFMVWTFFGQ-----LWRHF 1105
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6680908|ref|NP_031694.1| cyclin-dependent kinase 5
[Mus musculus]
         (292 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

01060                                                                 301   2e-82
14126                                                                 250   4e-67
01756                                                                 213   5e-56
20559                                                                 159   8e-55
01707                                                                 199   1e-51
29581                                                                 192   1e-49
01966                                                                 187   2e-49
23319                                                                 190   7e-49
04591                                                                 172   1e-43
32000                                                                 172   2e-43
04138                                                                 146   8e-36
18921                                                                 107   6e-24
13592                                                                 107   7e-24
00300                                                                 100   9e-22
24241                                                                  98   3e-21
03508                                                                  97   6e-21
06405                                                                  94   6e-20
12453                                                                  93   2e-19
03294                                                                  91   5e-19
12721                                                                  84   6e-17
09606                                                                  84   8e-17
15910                                                                  80   1e-15
01718                                                                  79   2e-15
17975                                                                  79   2e-15
19761                                                                  74   6e-14
13066                                                                  71   6e-13
03240                                                                  71   6e-13
28638                                                                  61   7e-13
26560                                                                  70   1e-12
21808                                                                  70   1e-12
27546                                                                  69   3e-12
14420                                                                  67   9e-12
21433                                                                  58   1e-11
04852                                                                  66   2e-11
31489                                                                  65   3e-11
27405                                                                  65   5e-11
09007                                                                  64   7e-11
18287                                                                  64   9e-11
19301                                                                  64   1e-10
11780                                                                  64   1e-10
00392                                                                  63   1e-10
19094                                                                  62   3e-10
16003                                                                  62   4e-10
30755                                                                  61   5e-10
07940                                                                  61   5e-10
32359                                                                  54   9e-10
18484                                                                  60   1e-09
14477                                                                  59   3e-09
00715                                                                  59   3e-09
13212                                                                  57   1e-08
21079                                                                  57   1e-08
14116                                                                  56   1e-08
11185                                                                  56   2e-08
26909                                                                  56   2e-08
31885                                                                  52   3e-07
17253                                                                  51   6e-07
26711                                                                  50   2e-06
18401                                                                  49   2e-06
16708                                                                  49   2e-06
37602                                                                  48   4e-06
07291                                                                  48   5e-06
01392                                                                  47   1e-05
17300                                                                  47   1e-05
01106                                                                  45   3e-05
22005                                                                  45   3e-05
00638                                                                  44   7e-05
12786                                                                  44   7e-05
28157                                                                  44   8e-05
06358                                                                  43   1e-04
20640                                                                  43   2e-04
36481                                                                  43   2e-04
02638                                                                  42   2e-04
11404                                                                  42   4e-04
05084                                                                  41   7e-04
13840                                                                  40   8e-04
26009                                                                  40   8e-04
15549                                                                  40   0.001
18481                                                                  40   0.001
21800                                                                  39   0.003
16350                                                                  37   0.011
31789                                                                  36   0.015
07836                                                                  35   0.035
12672                                                                  34   0.080
29360                                                                  33   0.12 
13078                                                                  33   0.13 
00394                                                                  32   0.29 
14104                                                                  29   2.6  
33679                                                                  28   3.7  
00842                                                                  28   4.0  
24983                                                                  28   5.3  
00331                                                                  28   5.9  
>01060
          Length = 1800

 Score =  301 bits (771), Expect = 2e-82,   Method: Compositional matrix adjust.
 Identities = 144/283 (50%), Positives = 198/283 (69%), Gaps = 3/283 (1%)
 Frame = +1

Query: 7   LEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKHKNIVRL 66
            +KIGEGTYG V+K ++R T   +A+K++RL   ++GVPSSA+REI +L+EL+H NIV L
Sbjct: 88  FQKIGEGTYGVVYKCRHRATGRKLAMKKIRLRGSEDGVPSSAIREIAMLRELRHTNIVCL 267

Query: 67  HDVLHSDKKLTLVFEFCDQDLKKYFDSC--NGDLDPEIVKSFLFQLLKGLGFCHSRNVLH 124
            DV+  D++L LVFEF   DLK Y D       LD  +VKS++FQ++ G+ FCH R ++H
Sbjct: 268 EDVIMEDERLFLVFEFLSMDLKMYIDKFPEGVVLDRRLVKSYVFQIVTGIXFCHQRRIVH 447

Query: 125 RDLKPQNLLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKLYSTSID 184
           RDLKPQNLLIN  G +K+ADFG+AR F +PVR Y+ EVVTLWYR P++L GA  YST +D
Sbjct: 448 RDLKPQNLLINHTGAIKIADFGMARTFALPVRAYTHEVVTLWYRAPEILMGASKYSTPVD 627

Query: 185 MWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQWPAMTKLPDYKP-YPMYP 243
           +WS G IFA++     P+F G+   DQL +IFR++GTPTE+ WP   KLP +   +P++ 
Sbjct: 628 VWSIGTIFADML-IRTPIFKGDSEIDQLFKIFRIIGTPTEQTWPEFHKLPAFNGMFPLWK 804

Query: 244 ATTSLVNVVPKLNATGRDLLQNLLKCNPVQRISAEEALQHPYF 286
               L   +  L++ G DL++  LKC+P QRIS ++ LQH YF
Sbjct: 805 E-GKLSETLTDLDSLGLDLIERTLKCDPAQRISCKKMLQHAYF 930
>14126
          Length = 1265

 Score =  250 bits (639), Expect = 4e-67,   Method: Compositional matrix adjust.
 Identities = 136/299 (45%), Positives = 192/299 (64%), Gaps = 12/299 (4%)
 Frame = +3

Query: 2   QKYEKLEKIGEGTYGTVFKAKN-RETHEIVALKRVRLDDDDEGVPSSALREICLLKELK- 59
           QKYE++  IG G YGTV+KA++ R   E VA+KR+RL++ +EG+P  A+REI +LK+L+ 
Sbjct: 189 QKYEEVAVIGNGAYGTVYKARDLRNQGEFVAMKRIRLNNTEEGMPMMAIREISMLKQLEQ 368

Query: 60  --HKNIVRLHDVLHS-----DKKLTLVFEFCDQDLKKYFDSC-NGDLDPEIVKSFLFQLL 111
             H N+VRL DV H+     + +L LVFE+ + DL  Y   C +  L P+ +K  + QLL
Sbjct: 369 YEHPNVVRLLDVSHNTITDREIRLNLVFEYIEHDLATYLAKCPSPGLGPDRIKDLMLQLL 548

Query: 112 KGLGFCHSRNVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPD 171
            G+ F HS  ++HRDLKPQNLLI+++G LKLADFGLAR +   +   +  VVTLWYR P+
Sbjct: 549 NGVDFLHSNRIVHRDLKPQNLLISKDGRLKLADFGLARIYSFHM-ALTTVVVTLWYRSPE 725

Query: 172 VLFGAKLYSTSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQWPAMT 231
           VL  A+ Y TS+D+WS GCIFAEL    R LF G+   DQLK+IF ++G P    WP   
Sbjct: 726 VLMQAE-YGTSVDIWSCGCIFAELFTR-RALFKGSSEFDQLKKIFEVIGLPPAGDWPEGV 899

Query: 232 KL--PDYKPYPMYPATTSLVNVVPKLNATGRDLLQNLLKCNPVQRISAEEALQHPYFSD 288
            +    ++P P  P  T    +VP+++   +DL++ +L     +RIS+ E+L HPY  D
Sbjct: 900 SVHRNSFRPTPPVPLQT----LVPEMDPQAKDLMEKMLVFKSGRRISSRESLLHPYLRD 1064
>01756
          Length = 1858

 Score =  213 bits (543), Expect = 5e-56,   Method: Compositional matrix adjust.
 Identities = 122/298 (40%), Positives = 178/298 (59%), Gaps = 14/298 (4%)
 Frame = -3

Query: 3    KYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKHKN 62
            KYEKL KIG+GT+G VFKA+ ++T ++VA+K+V +D++ EG P +ALREI +L+ L H+N
Sbjct: 1739 KYEKLAKIGQGTFGEVFKARCKKTKQVVAMKKVLMDNEKEGFPITALREIKILQLLNHEN 1560

Query: 63   IVRLHDVLHSDKK--------LTLVFEFCDQDLKKYFDSCNGDLDPEIVKSFLFQLLKGL 114
            +V L ++  +             LVFEFC+ DL     + +   +   +K  + QL+ GL
Sbjct: 1559 VVDLIEICSTKATSANRYKSMFYLVFEFCEHDLAGLLSNMSVVFNLPEIKEVMKQLMNGL 1380

Query: 115  GFCHSRNVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVRC---YSAEVVTLWYRPPD 171
             + H   +LHRD+K  N+LI + G LKLADFGLARAF + +R    Y+  VVTLWYRPP+
Sbjct: 1379 YYIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRVVTLWYRPPE 1200

Query: 172  VLFGAKLYSTSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQWPAMT 231
            +L G + YST+ID W AGCI AE+     P+  G    +QL  I +L G+ T E WP + 
Sbjct: 1199 LLLGDRNYSTAIDQWGAGCIMAEMWTRN-PIMQGTTEQNQLTLITQLCGSITPEVWPGVE 1023

Query: 232  KLPDYKPYPMYPATTSLVNVVPKL---NATGRDLLQNLLKCNPVQRISAEEALQHPYF 286
            +L  Y    +       V    +    +A   DLL  LL  +P +R++++EAL H +F
Sbjct: 1022 RLELYNSLDLPQGNKRKVKERLRYYIKDAYALDLLDKLLALDPGKRVNSDEALSHDFF 849
>20559
          Length = 430

 Score =  159 bits (402), Expect(3) = 8e-55,   Method: Compositional matrix adjust.
 Identities = 77/80 (96%), Positives = 80/80 (100%)
 Frame = -2

Query: 1   MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKH 60
           MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKH
Sbjct: 378 MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKH 199

Query: 61  KNIVRLHDVLHSDKKLTLVF 80
           +NIVRLHDVLHS++KLTLVF
Sbjct: 198 RNIVRLHDVLHSERKLTLVF 139

 Score = 68.2 bits (165), Expect(3) = 8e-55,   Method: Compositional matrix adjust.
 Identities = 29/37 (78%), Positives = 35/37 (94%)
 Frame = -3

Query: 80  FEFCDQDLKKYFDSCNGDLDPEIVKSFLFQLLKGLGF 116
           FE+CDQDLKKYFD+CNG++DP+ VKSFL QLL+GLGF
Sbjct: 140 FEYCDQDLKKYFDTCNGEIDPDTVKSFLHQLLRGLGF 30

 Score = 24.6 bits (52), Expect(3) = 8e-55,   Method: Compositional matrix adjust.
 Identities = 10/12 (83%), Positives = 10/12 (83%)
 Frame = -1

Query: 114 LGFCHSRNVLHR 125
           L FCHS NVLHR
Sbjct: 37  LVFCHSNNVLHR 2
>01707
          Length = 757

 Score =  199 bits (506), Expect = 1e-51,   Method: Compositional matrix adjust.
 Identities = 100/220 (45%), Positives = 139/220 (63%)
 Frame = +1

Query: 1   MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKH 60
           M+KYEK+ KIGEG+YG VFK +N+ET ++VA+K+    +DD  +   A+REI +LK+LKH
Sbjct: 61  MEKYEKIGKIGEGSYGVVFKCRNKETSQLVAIKKFVESEDDPLIKKIAMREIRMLKQLKH 240

Query: 61  KNIVRLHDVLHSDKKLTLVFEFCDQDLKKYFDSCNGDLDPEIVKSFLFQLLKGLGFCHSR 120
            N+VRL +V    K+L LVF++ D  L    D     L   +VK  ++Q L  + FCH  
Sbjct: 241 PNLVRLIEVFRRKKRLHLVFDYVDHTLLNELDRYPRGLPEPMVKRIIYQTLLAVNFCHQY 420

Query: 121 NVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKLYS 180
           N +HRD+KP+N+LI R G++KL DFG AR    P   Y+  V T WYR P++L G   Y 
Sbjct: 421 NTIHRDVKPENILITRQGQVKLCDFGFARILTGPGDEYTDYVATRWYRAPELLVGDTQYG 600

Query: 181 TSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLG 220
             +D+W+ GC+FAEL   G+ L+PG    DQL  I + LG
Sbjct: 601 PPVDVWAIGCVFAELL-TGQALWPGRSDVDQLHLIRKTLG 717
>29581
          Length = 1278

 Score =  192 bits (489), Expect = 1e-49,   Method: Compositional matrix adjust.
 Identities = 104/253 (41%), Positives = 149/253 (58%), Gaps = 3/253 (1%)
 Frame = -2

Query: 39   DDDEGVPSSALREICLLKELKHKNIVRLHDVL--HSDKKLTLVFEFCDQDLKKYFDSCNG 96
            + D   PS        L  L+H+NIV+L +V+   S   L LV E+C+QDL    D+   
Sbjct: 1241 ERDMVSPSVVCVRSTFLLNLRHQNIVQLQEVVVGKSLDSLFLVMEYCEQDLASLLDNMPA 1062

Query: 97   DLDPEIVKSFLFQLLKGLGFCHSRNVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVR 156
                  VK  + QLLKGL + H   ++HRDLK  NLL+   G +K+ADFGLAR +G P +
Sbjct: 1061 PFSESQVKCIVLQLLKGLRYLHEAFIIHRDLKVSNLLMTDKGCVKIADFGLARNYGKPQK 882

Query: 157  CYSAEVVTLWYRPPDVLFGAKLYSTSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIF 216
              + +VVTLWYR P++LFG+K +ST+IDMWSAGCI  EL    +PL PG     Q++ I 
Sbjct: 881  PMTPKVVTLWYRAPELLFGSKTHSTAIDMWSAGCILGELL-GHKPLMPGRSDLQQIELIM 705

Query: 217  RLLGTPTEEQWPAMTKLPDYKPYPMYPAT-TSLVNVVPKLNATGRDLLQNLLKCNPVQRI 275
             LLGTP +  WP  ++LP ++ + +      +L +  P L+ +G  LL  L   +P +R 
Sbjct: 704  ELLGTPNDTIWPGFSQLPAFEQFTLKKQPYNNLRHTFPWLSESGIRLLNGLFMYHPQKRA 525

Query: 276  SAEEALQHPYFSD 288
            +AE+ L+H YF +
Sbjct: 524  TAEDCLEHSYFKE 486

 Score = 33.5 bits (75), Expect = 0.10,   Method: Compositional matrix adjust.
 Identities = 14/31 (45%), Positives = 22/31 (70%)
 Frame = -1

Query: 27   HEIVALKRVRLDDDDEGVPSSALREICLLKE 57
            +EIVALK++R+  +  G+P S LREI +  +
Sbjct: 1278 NEIVALKKMRMTGERYGIPISGLREINIFAQ 1186
>01966
          Length = 1735

 Score =  187 bits (474), Expect(2) = 2e-49,   Method: Compositional matrix adjust.
 Identities = 87/172 (50%), Positives = 122/172 (70%), Gaps = 2/172 (1%)
 Frame = -1

Query: 22   KNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKHKNIVRLHDVLHSDKKLTLVFE 81
            ++R T   +A+K++RL   ++GVPSSA+REI +L+EL+H NIV L DV+  D++L LVFE
Sbjct: 1651 RHRATGRKLAMKKIRLRGSEDGVPSSAIREIAMLRELRHTNIVCLEDVIMEDERLFLVFE 1472

Query: 82   FCDQDLKKYFDSC--NGDLDPEIVKSFLFQLLKGLGFCHSRNVLHRDLKPQNLLINRNGE 139
            F   DLK Y D       LD  +VKS++FQ++ G+ FCH R ++HRDLKPQNLLIN  G 
Sbjct: 1471 FLSMDLKMYIDKFPEGVVLDRRLVKSYVFQIVTGINFCHQRRIVHRDLKPQNLLINHTGA 1292

Query: 140  LKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKLYSTSIDMWSAGCI 191
            +K+ADFG+AR F +PVR Y+ EVVTLWYR P++L G +   ++   W+ G +
Sbjct: 1291 IKIADFGMARTFALPVRAYTHEVVTLWYRAPEILMGPQ---STPPXWTCGAL 1145

 Score = 26.6 bits (57), Expect(2) = 2e-49,   Method: Compositional matrix adjust.
 Identities = 10/15 (66%), Positives = 13/15 (86%)
 Frame = -2

Query: 5    EKLEKIGEGTYGTVF 19
            ++L KIGEGTYG V+
Sbjct: 1701 DRLSKIGEGTYGVVY 1657

 Score = 99.8 bits (247), Expect = 1e-21,   Method: Compositional matrix adjust.
 Identities = 50/113 (44%), Positives = 72/113 (63%), Gaps = 1/113 (0%)
 Frame = -3

Query: 175  GAKLYSTSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQWPAMTKLP 234
            GA  YST +D+WS G IFA++     P+F G+   DQL +IFR++GTPTE+ WP   KLP
Sbjct: 1187 GASKYSTPVDVWSIGTIFADML-IRTPIFKGDSEIDQLFKIFRIIGTPTEQTWPEFHKLP 1011

Query: 235  DYKP-YPMYPATTSLVNVVPKLNATGRDLLQNLLKCNPVQRISAEEALQHPYF 286
             +   +P++     L   +  L++ G DL++  LKC+P QRIS ++ LQH YF
Sbjct: 1010 AFNGMFPLW-KEGKLSETLTDLDSLGLDLIERTLKCDPAQRISCKKMLQHAYF 855
>23319
          Length = 2235

 Score =  190 bits (482), Expect = 7e-49,   Method: Compositional matrix adjust.
 Identities = 91/122 (74%), Positives = 104/122 (85%)
 Frame = +3

Query: 170 PDVLFGAKLYSTSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQWPA 229
           PDV + AK+YSTSIDMWSAGCIFAELANAGRPLFPGND DDQLKRIF+LLGTPTE+QWP 
Sbjct: 3   PDV-YXAKMYSTSIDMWSAGCIFAELANAGRPLFPGNDDDDQLKRIFKLLGTPTEDQWPG 179

Query: 230 MTKLPDYKPYPMYPATTSLVNVVPKLNATGRDLLQNLLKCNPVQRISAEEALQHPYFSDF 289
           MT+LP+Y+ +PMY  TT+   VVPKLN+ GRDLLQ LL C P  R+SA+EALQHPYF+D 
Sbjct: 180 MTQLPNYRMFPMYHVTTTWQQVVPKLNSKGRDLLQCLLVCCPSDRMSADEALQHPYFADL 359

Query: 290 CP 291
            P
Sbjct: 360 PP 365
>04591
          Length = 1117

 Score =  172 bits (437), Expect = 1e-43,   Method: Compositional matrix adjust.
 Identities = 97/261 (37%), Positives = 145/261 (55%), Gaps = 16/261 (6%)
 Frame = -2

Query: 42   EGVPSSALREICLLKELKHKNIVRLHDVLHSD--------KKLTLVFEFCDQDLKKYFDS 93
            EG P +ALREI +L++L+H+N+V+L ++ H+             L+FE+CD DL    ++
Sbjct: 1098 EGFPITALREIKILQQLEHENVVQLQEICHTQAGPYNRYKSTFYLIFEYCDYDLAGLLNN 919

Query: 94   CNGDLDPEIVKSFLFQLLKGLGFCHSRNVLHRDLKPQNLLINRNGELKLADFGLARAFGI 153
                      K+ + QLL GL + H++ +LHRD+K  N+L+ R+G LKLADFGL+R + +
Sbjct: 918  LRVKFSLADKKNLMSQLLNGLFYIHTKQILHRDIKAANILLTRDGVLKLADFGLSRPW-V 742

Query: 154  PVRCYSAEVVTLWYRPPDVLFGAKLYSTSIDMWSAGCIFAELANAGRPLFPGNDVDDQLK 213
              +  +  VVTLWYRPP++L G + Y   IDMW  GCI AE+ +  +PL  G     QL 
Sbjct: 741  KSKRLTNRVVTLWYRPPELLLGEREYGPEIDMWGVGCIMAEMWSR-KPLMQGRSEQHQLS 565

Query: 214  RIFRLLGTPTEEQWPAMTK--------LPDYKPYPMYPATTSLVNVVPKLNATGRDLLQN 265
             I  L G+   E WP +TK        LP  KP  +      L+      N  G +L+  
Sbjct: 564  LITDLCGSLNAEVWPGVTKLELYGKLDLPQGKPRKVKERMLDLLK-----NKEGAELIDI 400

Query: 266  LLKCNPVQRISAEEALQHPYF 286
             L+ +P QR++ + AL H +F
Sbjct: 399  FLRLDPGQRMNCDNALSHDFF 337
>32000
          Length = 644

 Score =  172 bits (435), Expect = 2e-43,   Method: Compositional matrix adjust.
 Identities = 81/153 (52%), Positives = 107/153 (69%), Gaps = 1/153 (0%)
 Frame = -1

Query: 137 NGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKLYSTSIDMWSAGCIFAELA 196
             ++K+ADFGLAR FG+PVR Y+ EV+TLWYR P++L G + YS  +D+WS GCIF E+ 
Sbjct: 581 TAKMKIADFGLARVFGLPVRTYTHEVITLWYRAPEILLGCRFYSVPVDIWSLGCIFVEMM 402

Query: 197 NAGRPLFPGNDVDDQLKRIFRLLGTPTEEQWPAMTKLPDYKP-YPMYPATTSLVNVVPKL 255
              R LFPG+   DQL RIFR LGTP E+ WP ++KLPDYKP +P +P     +  V  L
Sbjct: 401 TR-RALFPGDSEIDQLYRIFRTLGTPDEKVWPGVSKLPDYKPTFPKWPLKN--LETVVSL 231

Query: 256 NATGRDLLQNLLKCNPVQRISAEEALQHPYFSD 288
           +  G DLL+ +L  NP +RISA  A++HPYF+D
Sbjct: 230 SKVGLDLLKRMLTYNPNRRISARSAMRHPYFND 132
>04138
          Length = 800

 Score =  146 bits (369), Expect = 8e-36,   Method: Compositional matrix adjust.
 Identities = 86/196 (43%), Positives = 112/196 (57%), Gaps = 9/196 (4%)
 Frame = +1

Query: 100 PEIVKSFLFQLLKGLGFCHSRNVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVRC-- 157
           PE  KS      + L + H   +LHRD+K  N+LI + G LKLADFGLARAF + +R   
Sbjct: 10  PESKKSIC*AADERLYYIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPN 189

Query: 158 -YSAEVVTLWYRPPDVLFGAKLYSTSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIF 216
            Y+  VVTLWYRPP++L G + YST+ID W AGCI AE+     P+  G    +QL  I 
Sbjct: 190 RYTNRVVTLWYRPPELLLGDRNYSTAIDQWGAGCIMAEMWTRN-PIMQGTTEQNQLTLIT 366

Query: 217 RLLGTPTEEQWPAMTKLPDYKPYPMYPATTSLVNVVPKLNAT------GRDLLQNLLKCN 270
           +L G+ T E WP +T+L  Y       A     N++    A       G DL + LLK +
Sbjct: 367 QLCGSITPEVWPGVTQLSMYHQIKGALAAGR-KNIIRDRFARILKDPYGLDLFERLLKMD 543

Query: 271 PVQRISAEEALQHPYF 286
           P QRISA+EAL H +F
Sbjct: 544 PSQRISADEALNHDFF 591
>18921
          Length = 697

 Score =  107 bits (267), Expect = 6e-24,   Method: Compositional matrix adjust.
 Identities = 62/201 (30%), Positives = 109/201 (54%), Gaps = 1/201 (0%)
 Frame = +2

Query: 4   YEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKHKNI 63
           ++ L K+GEG+YG+VFK+ ++ET +++A+K+V +D D + +    ++EI ++++   K I
Sbjct: 35  FDILGKLGEGSYGSVFKSLHKETGQVLAIKQVPVDTDLQEI----IKEISIMQQCDSKYI 202

Query: 64  VRLHDVLHSDKKLTLVFEFCDQ-DLKKYFDSCNGDLDPEIVKSFLFQLLKGLGFCHSRNV 122
           V+ +     +  L +V E+C    +       N  L    + + L+  LKGL + HSR  
Sbjct: 203 VKYYGSYFKNTDLWIVMEYCGAGSVSDIMRLRNKTLVEREIATILYYTLKGLXYLHSRRK 382

Query: 123 LHRDLKPQNLLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKLYSTS 182
           +HRD+K  N+L+N  G  KLADFG+A      +   +  + T ++  P+V+     Y   
Sbjct: 383 IHRDIKAGNILLNNEGHAKLADFGVAGQLTDTMAKRNTVIGTPYWMAPEVIQEIG-YDCV 559

Query: 183 IDMWSAGCIFAELANAGRPLF 203
            D+WS G    E+A    P+ 
Sbjct: 560 ADIWSLGITALEMAEGKPPVM 622
>13592
          Length = 980

 Score =  107 bits (266), Expect = 7e-24,   Method: Compositional matrix adjust.
 Identities = 76/292 (26%), Positives = 133/292 (45%), Gaps = 10/292 (3%)
 Frame = +2

Query: 9   KIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKHKNIVRLHD 68
           KIG+G +G V+ A N  T E++A+K + +   +     +   E+ +L+ +KHKN+VR + 
Sbjct: 5   KIGQGRFGKVYTAVNNNTGELMAMKEIAIQPGETRALKNVAEELKILEGIKHKNLVRYYG 184

Query: 69  VLHSDKKLTLVFEFCDQDLKKYFDSCNGDLDPEIVKSFLFQLLKGLGFCHSRNVLHRDLK 128
           +    ++L +  E C +   +      G L   + + F  QLL G+   H   ++HRD+K
Sbjct: 185 IEVHREELLIFMELCSEGTLESLVELTGGLPEALSRRFTAQLLSGVAELHKHGIVHRDIK 364

Query: 129 PQNL-LINRNGELKLADFGLARAFGIPVRCYS-------AEVVTLWYRPPDVL--FGAKL 178
             N+ L++ +  LKL DFG A    + ++ ++         V T  Y  P+V     +  
Sbjct: 365 TANIFLVDGSNSLKLGDFGSA----VKIQAHTTVPGELQGYVGTQAYMAPEVFTKTNSDG 532

Query: 179 YSTSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQWPAMTKLPDYKP 238
           +    D+WS GC+  E+A+  RP       D   + +F+ +G   + Q P          
Sbjct: 533 HGRLADIWSVGCVVVEMASGKRPW---AQFDSNFQIMFK-VGMGEKPQAP---------- 670

Query: 239 YPMYPATTSLVNVVPKLNATGRDLLQNLLKCNPVQRISAEEALQHPYFSDFC 290
                           L+  G D + + L+ +P QR+SA E L+     +FC
Sbjct: 671 --------------ESLSQEGHDFIDHCLQHDPKQRLSAIELLEQ----NFC 772
>00300
          Length = 2318

 Score =  100 bits (248), Expect = 9e-22,   Method: Compositional matrix adjust.
 Identities = 76/295 (25%), Positives = 143/295 (48%), Gaps = 12/295 (4%)
 Frame = -1

Query: 3    KYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREIC----LLKEL 58
            ++++  KIGEG +G V+ A N  T E++ALK ++   +D       LRE+C    + + +
Sbjct: 1655 RWQRGNKIGEGQFGKVYTAVNMSTGELMALKEMKFQPND----LQQLREMCDEIKIFEGI 1488

Query: 59   KHKNIVRLHDV-LHSDKKLTLVFEFCDQDLKKYFDSCNGDLDPEIVKSFLFQLLKGLGFC 117
            +H+N+V+ + V +H D+ L +  E+CD    +  ++    L   +++ +  +++  +   
Sbjct: 1487 QHENLVKYYGVEVHKDEML-MFMEYCDTGTIE--EAAKMGLPEYLIRRYTREIVLAVNHL 1317

Query: 118  HSRNVLHRDLKPQNLLINRNGELKLADFG----LARAFGIPVRCYSAEVVTLWYRPPDVL 173
            H  +++HRD+K  N+ +  NG +KL DFG    L     +P   ++  V T  Y  P+V 
Sbjct: 1316 HENSIVHRDIKGANIFLTSNGHVKLGDFGCSVKLKSHTTMPGEFHNL-VGTTAYMAPEVF 1140

Query: 174  FGAKL--YSTSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRL-LGTPTEEQWPAM 230
                   Y  + D+WS GC+  E+A   RP    +D+D+  + ++++ +G       PA 
Sbjct: 1139 TQNDQGGYGRAADIWSLGCVVIEMATGKRPW---HDLDNNYQIMYKVGIG-----HKPA- 987

Query: 231  TKLPDYKPYPMYPATTSLVNVVPKLNATGRDLLQNLLKCNPVQRISAEEALQHPY 285
              +PD                   L+  G+  L  ++  +P QR  A + L H +
Sbjct: 986  --VPD------------------SLSVEGKHFLDLIMCHDPAQRALASQLLDHTF 882
>24241
          Length = 413

 Score = 98.2 bits (243), Expect = 3e-21,   Method: Compositional matrix adjust.
 Identities = 52/116 (44%), Positives = 78/116 (67%), Gaps = 3/116 (2%)
 Frame = -2

Query: 5   EKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKH-KNI 63
           ++L KIGEGTYG V+K ++R T   +A+K++RL   ++GVPSSA+REI +L+EL+H + +
Sbjct: 334 DRLSKIGEGTYGVVYKCRHRATGRKLAMKKIRLRGSEDGVPSSAIREIAMLRELRHTQXL 155

Query: 64  VRLHDVLHSDKKLTLVFEFCDQDLKKYFDSCNGDLDPE--IVKSFLFQLLKGLGFC 117
           V L DV+  D++L LVFEF   DLK Y D       PE  ++   L +++ G+ FC
Sbjct: 154 VCLEDVIMEDERLFLVFEFLSMDLKMYIDKF-----PEGVVLDRRLVKIVTGINFC 2
>03508
          Length = 1463

 Score = 97.4 bits (241), Expect = 6e-21,   Method: Compositional matrix adjust.
 Identities = 64/205 (31%), Positives = 105/205 (51%), Gaps = 4/205 (1%)
 Frame = +1

Query: 4   YEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKHKNI 63
           Y+ + K+G G Y  VF+A N   +E    K V                  L       N+
Sbjct: 595 YQIVRKLGRGKYSEVFEAINVTNNE----KCVIKILKPVKKKKIKREIKILENLRGGTNV 762

Query: 64  VRLHDVLHSDKKLT--LVFEFCDQ-DLKKYFDSCNGDLDPEIVKSFLFQLLKGLGFCHSR 120
           + L  ++      T  L+FE  +  D K+ + +   D D   ++ +L++L+K L FCHS 
Sbjct: 763 ITLLAIVKDPVSRTPALIFEHVNNTDFKQLYQTFT-DYD---IRFYLYELMKALDFCHSM 930

Query: 121 NVLHRDLKPQNLLINR-NGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKLY 179
            ++HRD+KP N++I+  N +L+L D+GLA  F  P   Y+  V + +++ P++L   ++Y
Sbjct: 931 GIMHRDVKPHNVMIDHENKKLRLIDWGLAE-FYHPGMEYNVRVASRYFKGPELLLDYQMY 1107

Query: 180 STSIDMWSAGCIFAELANAGRPLFP 204
             S+DMWS GC+FA +     PL P
Sbjct: 1108DYSLDMWSLGCMFASMIFRKEPLLP 1182
>06405
          Length = 1965

 Score = 94.0 bits (232), Expect = 6e-20,   Method: Compositional matrix adjust.
 Identities = 68/228 (29%), Positives = 115/228 (50%), Gaps = 12/228 (5%)
 Frame = +1

Query: 9   KIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKHKNIVRLHD 68
           ++G G YG V++A  +  ++IVA+K ++   +D    +  L E  ++KE+KH N+V+L  
Sbjct: 280 RLGGGQYGDVYEAMWKRYNKIVAVKTLK---EDTMALNDFLEEAAIMKEMKHPNLVQLLG 450

Query: 69  VLHSDKKLTLVFEFCDQ-DLKKYFDSCNGDLD-PEIVKSFLFQLLKGLGFCHSRNVLHRD 126
           V   +    +V EF    +L  Y  S   + + P  +     Q+  G+ +  ++N +HRD
Sbjct: 451 VCTREPPFYIVTEFMPHGNLLDYLRSSTREENGPTALMYMATQIASGMAYLETKNFIHRD 630

Query: 127 LKPQNLLINRNGELKLADFGLARAFGIPVRCYSAEVVT----LWYRPPDVLFGAKLYSTS 182
           L  +N L+  +  +K+ADFGLAR        Y+A +       W  P  + F    +ST 
Sbjct: 631 LAARNCLVADSNMVKVADFGLARLMKD--DTYTAHIGAKFPIKWTAPEGLAFNR--FSTR 798

Query: 183 IDMWSAGCIFAELANAGRPLFPG---NDVDDQLKRIFRLL---GTPTE 224
            D+W+ G +  ELA  G   +PG    +V   L+R +R+    GTP +
Sbjct: 799 SDIWAFGVLLWELATYGMSPYPGVELTEVYHLLERGYRMERPPGTPAD 942
>12453
          Length = 680

 Score = 92.8 bits (229), Expect = 2e-19,   Method: Compositional matrix adjust.
 Identities = 46/105 (43%), Positives = 69/105 (65%), Gaps = 2/105 (1%)
 Frame = +3

Query: 189 GCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQWPAMTKLPDYKP--YPMYPATT 246
           GCIF E+A  GRPLFPG+ V+D+L  IF+ LGTPTE+  P++++ PD+     P Y    
Sbjct: 9   GCIFYEMA-CGRPLFPGSTVEDELHLIFKTLGTPTEDSLPSISRNPDFLALNLPHYQG-E 182

Query: 247 SLVNVVPKLNATGRDLLQNLLKCNPVQRISAEEALQHPYFSDFCP 291
           +L+ + P+L++ G DLL   LK N   R+SA ++L+H +F+   P
Sbjct: 183 ALITIAPRLDSDGLDLLAKFLKYNAKIRVSAADSLKHSFFNSLGP 317
>03294
          Length = 1684

 Score = 91.3 bits (225), Expect = 5e-19,   Method: Compositional matrix adjust.
 Identities = 45/105 (42%), Positives = 67/105 (63%), Gaps = 1/105 (0%)
 Frame = -1

Query: 183  IDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQWPAMTKLPDYKP-YPM 241
            +D+WS G IFA++     P+F G+   DQL +IFR++GTPTE+ WP   KLP +   +P+
Sbjct: 1672 VDVWSIGTIFADML-IRTPIFKGDSEIDQLFKIFRIIGTPTEQTWPEFHKLPAFNGMFPL 1496

Query: 242  YPATTSLVNVVPKLNATGRDLLQNLLKCNPVQRISAEEALQHPYF 286
            +     L   +  L++ G DL++  LKC+P QRIS ++ LQH YF
Sbjct: 1495 W-KEGKLSETLTDLDSLGLDLIERTLKCDPAQRISCKKMLQHAYF 1364
>12721
          Length = 821

 Score = 84.3 bits (207), Expect = 6e-17,   Method: Compositional matrix adjust.
 Identities = 53/196 (27%), Positives = 99/196 (50%), Gaps = 1/196 (0%)
 Frame = +1

Query: 9   KIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKHKNIVRLHD 68
           KIGEG+ G V  A +R+  ++   K   +D   +        E+ ++++  H NIV +++
Sbjct: 109 KIGEGSTGIVCIATSRDGRQMAVKK---MDLRKQQRRELLFNEVVVMRDYHHPNIVEMYN 279

Query: 69  VLHSDKKLTLVFEFCDQDLKKYFDSCNGDLDPEIVKSFLFQLLKGLGFCHSRNVLHRDLK 128
               + +L +V EF +          N  +D   + +     LK L F H+  V+HRD+K
Sbjct: 280 SYLVNDELWVVMEFMEGGALTDI-VTNNRMDEVQIATVCRACLKALAFLHANGVIHRDIK 456

Query: 129 PQNLLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKL-YSTSIDMWS 187
             ++L++ +G++KL DFG        ++   + V T ++  P+V+  ++L Y   +D+WS
Sbjct: 457 SDSILLSHDGKVKLXDFGFCAQVTQDLQKRKSLVGTPYWMAPEVI--SRLPYGPEVDIWS 630

Query: 188 AGCIFAELANAGRPLF 203
            G +  E+ +A  P F
Sbjct: 631 LGIMVMEMIDAEPPFF 678
>09606
          Length = 1300

 Score = 83.6 bits (205), Expect = 8e-17,   Method: Compositional matrix adjust.
 Identities = 70/308 (22%), Positives = 130/308 (42%), Gaps = 22/308 (7%)
 Frame = -3

Query: 1    MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKH 60
            M+ +   E++G+G +  ++K + + T   VA+  +      E         + +  ++ H
Sbjct: 1118 MENFVLYEELGKGEHSIIYKGRRKGTINFVAIHCIEKCKRPE-----VTNTVRMTHDISH 954

Query: 61   KNIVRLHDVLHSDKKLTLVFEFCDQDLKKYFDSCNGDLDPEIVKSFLFQLLKGLGFCHSR 120
             N+V+ H+   +   L LV E C         + +  L    ++ F   L+ GL + HS 
Sbjct: 953  PNVVQFHEWYETSNHLWLVVELCTGGSLADILAQDHHLPETSIRDFGIHLVTGLHYIHSL 774

Query: 121  NVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVR---CYSAEVVTLW----------- 166
             +L  DL+P  +L++ +G LK ADFGL++  G  +       AE    W           
Sbjct: 773  GILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEAGDQWNIQSAEEMMKQ 594

Query: 167  --------YRPPDVLFGAKLYSTSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRL 218
                    Y  P+V  GA+  S   D+W+ GC+F E+  +G P F G   D    ++   
Sbjct: 593  VPTSGSPTYMAPEVFQGAEP-SIMSDLWALGCVFYEMF-SGHPPFLGETYDITKDKVLN- 423

Query: 219  LGTPTEEQWPAMTKLPDYKPYPMYPATTSLVNVVPKLNATGRDLLQNLLKCNPVQRISAE 278
                              K +P+     S ++  P  +    +LL++LL+ +  +R+S  
Sbjct: 422  ------------------KEFPLPKVKGSRLSAKP--SPEFLNLLESLLQKDSTRRLSWA 303

Query: 279  EALQHPYF 286
              ++H ++
Sbjct: 302  SLVKHAFW 279
>15910
          Length = 1361

 Score = 79.7 bits (195), Expect = 1e-15,   Method: Compositional matrix adjust.
 Identities = 57/179 (31%), Positives = 89/179 (49%), Gaps = 3/179 (1%)
 Frame = +2

Query: 110 LLKGLGFCHSRNVLHRDLKPQNLL---INRNGELKLADFGLARAFGIPVRCYSAEVVTLW 166
           +L G+ + H+  V+HRDLKP+NLL   +  + +LKLADFGL+R     V+  S    T  
Sbjct: 491 ILHGVQYIHANGVVHRDLKPENLLYECMTDDSKLKLADFGLSRIIEPEVQ-MSTVCGTPG 667

Query: 167 YRPPDVLFGAKLYSTSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQ 226
           Y  P+VL G K Y+ S+DMWS G I   L     P F  N+  +  ++I +      EE 
Sbjct: 668 YCAPEVLKGDK-YTPSVDMWSVGVIAYILLCGYEPFFAENEF-EMYRKIIKGEYKFDEEY 841

Query: 227 WPAMTKLPDYKPYPMYPATTSLVNVVPKLNATGRDLLQNLLKCNPVQRISAEEALQHPY 285
           W                          +++   +D+++ LL  +P +R++A EAL+ P+
Sbjct: 842 W-------------------------SEISENAKDVVRKLLVIDPKKRLTATEALRLPW 943
>01718
          Length = 959

 Score = 79.0 bits (193), Expect = 2e-15,   Method: Compositional matrix adjust.
 Identities = 59/195 (30%), Positives = 95/195 (48%), Gaps = 6/195 (3%)
 Frame = +3

Query: 8   EKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKHKNIVRLH 67
           EKIG G +  VFK  +R T +++ALK   +  +   +    LRE+ LL  L+H NI+R  
Sbjct: 165 EKIGAGFFSEVFKVTHRITGQVMALKMNTMTSNRHNM----LREVQLLNRLQHANILRFM 332

Query: 68  DVLHSDKKLTLVFEFC-DQDLKKYFDSCNGDLDPEIVKSFLFQLLKGLGFCHSRNVLHRD 126
            V   + +L  + E+    +L++  +  + +L           L +GL + HS   +HRD
Sbjct: 333 GVCVHEGQLHALTEYIPSGNLEQLLEKKDEELPWTQRIQLTLGLARGLDYLHSTRFIHRD 512

Query: 127 LKPQNLLINRNG----ELKLADFGLARAFGIPVRCYSAEVV-TLWYRPPDVLFGAKLYST 181
           L  +N+LI R         +ADFGLA     P+       V + ++  P+VL G   Y+ 
Sbjct: 513 LTSKNILIRREDNHGYHAVIADFGLATKIPDPLDKEKLPTVGSPYWMAPEVLNG-HFYNE 689

Query: 182 SIDMWSAGCIFAELA 196
             D++S G I  E+ 
Sbjct: 690 RADLFSVGIIMCEIT 734
>17975
          Length = 449

 Score = 79.0 bits (193), Expect = 2e-15,   Method: Compositional matrix adjust.
 Identities = 45/136 (33%), Positives = 80/136 (58%), Gaps = 2/136 (1%)
 Frame = +3

Query: 15  YGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKHKNIVRLHDVLHSDK 74
           +  V  A++  T E VA+K +     DE   S   +E+  +K ++H N+VRL++V+ +  
Sbjct: 6   FAVVKLARHVFTGEKVAVKVIDKTKLDEVSRSHLFQEVRCMKLVQHPNVVRLYEVIDTQT 185

Query: 75  KLTLVFEFCDQ-DLKKYFDSCNGDLDPEIVKSFLFQLLKGLGFCHSRNVLHRDLKPQNLL 133
           KL L+ E  D  D+  Y    +G L+ ++ K +  Q+++ + +CH  +V+HRDLKP+N++
Sbjct: 186 KLYLILELGDGGDMYDYIMRHSGGLEEKLAKRYFRQIVEAISYCHKLHVVHRDLKPENVV 365

Query: 134 -INRNGELKLADFGLA 148
              + G +KL DFG +
Sbjct: 366 FFEKPGLVKLTDFGFS 413
>19761
          Length = 473

 Score = 73.9 bits (180), Expect = 6e-14,   Method: Compositional matrix adjust.
 Identities = 43/140 (30%), Positives = 73/140 (52%), Gaps = 3/140 (2%)
 Frame = -3

Query: 100 PE-IVKSFLFQLLKGLGFCHSRN--VLHRDLKPQNLLINRNGELKLADFGLARAFGIPVR 156
           PE ++  +L Q    L + H+    +LHRDLKPQN+ +   G+++L D GLAR    P  
Sbjct: 429 PERLIVCWLMQTASALNYMHTHTPVILHRDLKPQNIYVTEKGDVRLGDLGLARKLTGPAD 250

Query: 157 CYSAEVVTLWYRPPDVLFGAKLYSTSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIF 216
             +++V T+ Y  P++L   + Y++  D+WS GC+F ++         G    D++  +F
Sbjct: 249 FATSQVGTIMYLSPEIL-SQQPYNSKSDIWSLGCVFYDIT--------GKKGSDEMGVMF 97

Query: 217 RLLGTPTEEQWPAMTKLPDY 236
            L+      + P    LPD+
Sbjct: 96  LLVQVMGGRKLP----LPDH 49
>13066
          Length = 551

 Score = 70.9 bits (172), Expect = 6e-13,   Method: Compositional matrix adjust.
 Identities = 47/149 (31%), Positives = 74/149 (49%), Gaps = 9/149 (6%)
 Frame = +3

Query: 50  REICLLKELKHKNIVRLHDVLHSDKKLTLVFEFCDQ-DLKKYFDSCNGDLDPEIVKSFLF 108
           RE+ LL +L H  I+++H +L    K  +   F ++ DL  Y     G +  +  K + +
Sbjct: 123 RELDLLTKLDHPYIIQIHSILQRXPKNFIFMRFAERGDLLTYIQEV-GFVKEKQAKIWFY 299

Query: 109 QLLKGLGFCHSRNVLHRDLKPQNLLINRNGELKLADFGLARA--------FGIPVRCYSA 160
           Q+   L + HS +V HRDLK +N+L++ +  +KLADFG A A        +     C SA
Sbjct: 300 QMTTALNYLHSYDVAHRDLKCENILLSSHFNVKLADFGFACACITESGEKYMSRTYCGSA 479

Query: 161 EVVTLWYRPPDVLFGAKLYSTSIDMWSAG 189
                 Y  P++++GA       D WS G
Sbjct: 480 A-----YAAPEIVYGAPYAPKVADAWSLG 551
>03240
          Length = 1683

 Score = 70.9 bits (172), Expect = 6e-13,   Method: Compositional matrix adjust.
 Identities = 69/279 (24%), Positives = 111/279 (39%), Gaps = 48/279 (17%)
 Frame = -3

Query: 4    YEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDD---DDEGVPSSALREICLLKELKH 60
            +EK++ +G G +G V   +  +T  + A+K +R  D    ++     A R+I  L E  +
Sbjct: 1285 FEKIKTLGVGAFGEVSLCRKNDTGMLYAMKTLRKSDVLKRNQVAHVKAERDI--LAEADN 1112

Query: 61   KNIVRLHDVLHSDKKLTLVFEFC-DQDLKKYFDSCNGDLDPEIVKSFLFQLLKGLGFCHS 119
            + +V+L+        L  V ++    DL          LD  + + ++ +L++ +   H 
Sbjct: 1111 EWVVKLYYSFQDHNYLYFVMDYVPGGDLMGLLIRME-ILDEPLARFYVAELVQAIESVHR 935

Query: 120  RNVLHRDLKPQNLLINRNGELKLADFGL-------------------ARAFGIPVRCYSA 160
               +HRD+KP N+LI+RNG +KL DFGL                   AR   + V+C   
Sbjct: 934  MGFIHRDIKPDNILIDRNGHIKLTDFGLCTGFRWTHNSKYYQRDGTHARQDSMEVKCQLD 755

Query: 161  E-------------------------VVTLWYRPPDVLFGAKLYSTSIDMWSAGCIFAEL 195
            E                         V T  Y  P+VL     Y++  D WS G I  E+
Sbjct: 754  EQCQCEILKPLERRRKREQRCLAHSLVGTPNYIAPEVLSRLGGYTSVCDWWSVGVILFEM 575

Query: 196  ANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQWPAMTKLP 234
                 P +     + Q K I           W  M K+P
Sbjct: 574  LVGHPPFYANTPAETQYKVI----------NWKDMLKIP 488
>28638
          Length = 1458

 Score = 61.2 bits (147), Expect(2) = 7e-13,   Method: Compositional matrix adjust.
 Identities = 37/105 (35%), Positives = 56/105 (53%), Gaps = 4/105 (3%)
 Frame = -1

Query: 102 IVKSFLFQLLKGLGFCHS--RNVLHRDLKPQNLLIN--RNGELKLADFGLARAFGIPVRC 157
           + + F  QL   L F  +   N++H DLKP+N+L+   +   +K+ DFG +   G  +  
Sbjct: 834 LTRKFAQQLCTALLFLATPEMNIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQ 655

Query: 158 YSAEVVTLWYRPPDVLFGAKLYSTSIDMWSAGCIFAELANAGRPL 202
           Y   + + +YR P+VL G   Y  +IDMWS GCI  E+     PL
Sbjct: 654 Y---IQSRFYRSPEVLLGVP-YDLAIDMWSLGCILVEMHTGEPPL 532

 Score = 29.3 bits (64), Expect(2) = 7e-13,   Method: Compositional matrix adjust.
 Identities = 27/93 (29%), Positives = 44/93 (47%), Gaps = 6/93 (6%)
 Frame = -3

Query: 1    MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKH 60
            + +YE    IG+G++G V KA +    E VA+K ++   + +   + A  E+ LL+ +  
Sbjct: 1150 LDRYEIDSLIGKGSFGQVVKAYDHGDQEQVAIKIIK---NKKPFLNQAQIEVKLLELMNR 980

Query: 61   KN------IVRLHDVLHSDKKLTLVFEFCDQDL 87
             +      IVRL         L LVFE    +L
Sbjct: 979  HDADNXYYIVRLKRHFMFRNHLCLVFELLSYNL 881

 Score = 28.5 bits (62), Expect = 3.3,   Method: Compositional matrix adjust.
 Identities = 34/131 (25%), Positives = 49/131 (37%), Gaps = 34/131 (25%)
 Frame = -2

Query: 190 CIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPTE---EQWPAMTKLPDYKPYPMY---- 242
            ++      G PLF G++  DQ+ +I  +LG P     +Q     K  D  P   Y    
Sbjct: 572 AVYWWRCTXGNPLFAGSNEFDQMMKIVEVLGVPPRHILDQAQKTRKYFDLLPDGTYAPKK 393

Query: 243 ---------PATTSLVNVV--PKLNATGR----------------DLLQNLLKCNPVQRI 275
                    P++  L  V+   K    GR                DL+  +L  +P  RI
Sbjct: 392 PRDNKKYKSPSSRKLHEVLGAEKGGPGGRRMGEPGHTVADYLKFKDLILRMLDFDPKTRI 213

Query: 276 SAEEALQHPYF 286
           S   ALQH +F
Sbjct: 212 SPYYALQHNFF 180
>26560
          Length = 398

 Score = 70.1 bits (170), Expect = 1e-12,   Method: Compositional matrix adjust.
 Identities = 41/126 (32%), Positives = 67/126 (53%)
 Frame = -1

Query: 90  YFDSCNGDLDPEIVKSFLFQLLKGLGFCHSRNVLHRDLKPQNLLINRNGELKLADFGLAR 149
           Y  S +G    + V+ +  +++ GL   HSR V++RDLKP N+L++ NG ++++D GLA 
Sbjct: 389 YHLSQHGVFTEKEVRFYAAEVMLGLEHMHSRFVVYRDLKPANILLDENGHVRISDLGLAC 210

Query: 150 AFGIPVRCYSAEVVTLWYRPPDVLFGAKLYSTSIDMWSAGCIFAELANAGRPLFPGNDVD 209
            F    +   A V T  Y  P+VL   + Y +S D +S GC+  +L     P    N   
Sbjct: 209 DF--SKKRPHASVGTHGYMAPEVLMKGQSYDSSADWFSFGCMLYKLLKGHSPFRQHNQGQ 36

Query: 210 DQLKRI 215
            ++ R+
Sbjct: 35  ARIDRM 18
>21808
          Length = 1011

 Score = 70.1 bits (170), Expect = 1e-12,   Method: Compositional matrix adjust.
 Identities = 53/197 (26%), Positives = 93/197 (47%), Gaps = 8/197 (4%)
 Frame = +1

Query: 30  VALKRVRLDDDDEGVPSSALREICLLKELKHKNIVRLHDVLHSDKKLTLVFEFC-DQDLK 88
           VA+K ++    D   P   L E  ++K+L+H  +++L+ V   D  + ++ E   +  L 
Sbjct: 28  VAIKTLKSGTMD---PKDFLAEAQIMKKLRHPKLIQLYAVCTQDDPIFIITELMKNGSLL 198

Query: 89  KYFDSCNGDLDPEIVKSFLFQLLKGLGFCHSRNVLHRDLKPQNLLINRNGELKLADFGLA 148
           ++       L    +     Q+  G+ +  S+N +HRDL  +N+L++ N  +K+ADFGLA
Sbjct: 199 EFLQGKGRVLKLPALIDIGAQIACGMAYLESQNYIHRDLAARNILVSDNNTVKIADFGLA 378

Query: 149 RAFGIPVRCYSAEVVTL----WYRPPDVLFGAKLYSTSIDMWSAGCIFAELANAGRPLFP 204
           R   I    Y A V       W  P    +    ++   D+WS G +  E    GR  +P
Sbjct: 379 RV--IKEDEYEARVGARFPIKWTAPEAANYNR--FTIKSDVWSFGILLTETVTYGRVPYP 546

Query: 205 G---NDVDDQLKRIFRL 218
           G    +V  Q++  +R+
Sbjct: 547 GMTNAEVLHQVEHGYRM 597
>27546
          Length = 426

 Score = 68.6 bits (166), Expect = 3e-12,   Method: Compositional matrix adjust.
 Identities = 34/101 (33%), Positives = 60/101 (59%), Gaps = 1/101 (0%)
 Frame = -1

Query: 50  REICLLKELKHKNIVRLHDVLHSDKKLTLVFEFCDQ-DLKKYFDSCNGDLDPEIVKSFLF 108
           RE+ +L  L H NI+++H +L    K+ +   + ++ D+  +     G +D    K + F
Sbjct: 333 RELEILTRLDHPNIIQIHSILQRGPKIFIFMRYAEKGDMLSHIKK-TGPIDEAQTKVWFF 157

Query: 109 QLLKGLGFCHSRNVLHRDLKPQNLLINRNGELKLADFGLAR 149
           Q+ K L + HS ++ HRDLK +N+L+++   +K+ADFG AR
Sbjct: 156 QMAKALQYLHSHDIAHRDLKCENILLSKRLNVKIADFGFAR 34
>14420
          Length = 528

 Score = 67.0 bits (162), Expect = 9e-12,   Method: Compositional matrix adjust.
 Identities = 44/160 (27%), Positives = 75/160 (46%), Gaps = 2/160 (1%)
 Frame = +2

Query: 49  LREICLLKELKHKNIVRLHDVLHSDKKLTLVFEFCDQD--LKKYFDSCNGDLDPEIVKSF 106
           + EI +++E ++ NIV   D     ++L +V EF           ++C   +D   + + 
Sbjct: 44  INEILVMRENQNPNIVNYLDSYLVGEELWVVMEFLAGGSLTDVVTETC---MDEGQIAAV 214

Query: 107 LFQLLKGLGFCHSRNVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVRCYSAEVVTLW 166
             + L+ L F H   V+HRD+K  N+L+  +G +KL DFG            S  V T +
Sbjct: 215 CRECLQALEFLHENQVIHRDIKSDNILLGMDGSVKLTDFGFCAQLSPEQSKRSTMVGTPY 394

Query: 167 YRPPDVLFGAKLYSTSIDMWSAGCIFAELANAGRPLFPGN 206
           +  P+V+   K Y  ++D+WS G +  E+     P    N
Sbjct: 395 WMAPEVV-TRKQYGPTVDIWSLGVMCIEMIEGEPPYLNEN 511
>21433
          Length = 590

 Score = 58.2 bits (139), Expect(2) = 1e-11,   Method: Compositional matrix adjust.
 Identities = 37/97 (38%), Positives = 57/97 (58%)
 Frame = +2

Query: 106 FLFQLLKGLGFCHSRNVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVRCYSAEVVTL 165
           +++QL   L +CH R V+HRD+KP+NLL+   G+LK+ADFG   +   P    +    TL
Sbjct: 182 YIYQLSSALEYCHYRKVIHRDIKPENLLLGLKGDLKIADFGW--SVHAPSSRRTTMCGTL 355

Query: 166 WYRPPDVLFGAKLYSTSIDMWSAGCIFAELANAGRPL 202
            Y PP+++ G K +  ++D+WS G +  E      PL
Sbjct: 356 DYLPPEMVEG-KTHDENVDLWSLGVLCYEFLVGTPPL 463

 Score = 28.5 bits (62), Expect(2) = 1e-11,   Method: Compositional matrix adjust.
 Identities = 15/47 (31%), Positives = 25/47 (53%), Gaps = 1/47 (2%)
 Frame = +3

Query: 50 REICLLKELKHKNIVRLHDVLHSDKKLTLVFEFCDQ-DLKKYFDSCN 95
          REI +   L+H NI+R+    H   ++ L+ EF  + +L K    C+
Sbjct: 15 REIEIQSHLRHDNILRMFGYFHDKTRVYLILEFAPKGELYKELQRCH 155
>04852
          Length = 1462

 Score = 66.2 bits (160), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 49/180 (27%), Positives = 87/180 (48%), Gaps = 29/180 (16%)
 Frame = +1

Query: 49  LREICLLKELK----HKNIVRLHDVLHSDKKLTLVFEFC-DQDLKKYFDSCNGDL----- 98
           ++E+ ++K +K    H NIV           L ++ EF  + +L+ + +SC   +     
Sbjct: 82  VQELQVMKAVKKMGSHINIVNFLGCCTQGGPLWVIVEFAKNGNLRDFLESCRDGINGYGK 261

Query: 99  -----DP---------EIVK-----SFLFQLLKGLGFCHSRNVLHRDLKPQNLLINRNGE 139
                DP          +++     S+ FQ+ +G+ F  SR  +HRDL  +N+L+     
Sbjct: 262 FVSPQDPGWYTKTPGGHVIRRKNLLSYAFQIARGMEFLASRKCIHRDLAARNVLVTEEHV 441

Query: 140 LKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKLYSTSIDMWSAGCIFAELANAG 199
           LK+ADFGL+R  G   +  S   + + +  P+ LF  + Y+T  D+WS G +  E+ + G
Sbjct: 442 LKIADFGLSRT-GDYYKKRSGGRLPVKWMAPEALFDMR-YTTKSDVWSFGVVLWEIFSLG 615
>31489
          Length = 329

 Score = 65.1 bits (157), Expect = 3e-11,   Method: Compositional matrix adjust.
 Identities = 36/88 (40%), Positives = 54/88 (61%), Gaps = 6/88 (6%)
 Frame = +3

Query: 52  ICLLKELKHKNIVRLHDVL------HSDKKLTLVFEFCDQDLKKYFDSCNGDLDPEIVKS 105
           I +LK  KH NI+ + ++L      H  K + +VF+  + DL +   S +  L  E ++ 
Sbjct: 3   IKILKHFKHDNIISIREILKPKDSYHDFKDIHVVFDLMESDLHRIIYS-DQPLTEEHIRY 179

Query: 106 FLFQLLKGLGFCHSRNVLHRDLKPQNLL 133
           FL+Q+L+GL + HS NV+HRDLKP NLL
Sbjct: 180 FLYQILRGLKYIHSANVVHRDLKPSNLL 263
>27405
          Length = 532

 Score = 64.7 bits (156), Expect = 5e-11,   Method: Compositional matrix adjust.
 Identities = 49/179 (27%), Positives = 89/179 (49%), Gaps = 9/179 (5%)
 Frame = -3

Query: 15  YGTVFKAKNRETHEIVALK-----RVRLDDDDEGVPSSALREICLLKELKHKN----IVR 65
           +G V+  +  +T ++ A+K     R+++    +G  + AL E  +L  +        IV 
Sbjct: 527 FGEVYGCRKADTGKMYAMKCLDKKRIKM----KGGETLALNERIMLSLVSTGEGSPFIVC 360

Query: 66  LHDVLHSDKKLTLVFEFCDQDLKKYFDSCNGDLDPEIVKSFLFQLLKGLGFCHSRNVLHR 125
           +     + +KL  + +  +     Y  S +G    + V+ +  +++ GL   HSR V++R
Sbjct: 359 MTYAFQTPEKLCFILDLMNGGDLHYHLSQHGVFTEKEVRFYAAEVMLGLEHMHSRFVVYR 180

Query: 126 DLKPQNLLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKLYSTSID 184
           DLKP N+L++ NG ++++D GLA  F    +   A V T  Y  P+VL   + Y +S D
Sbjct: 179 DLKPANILLDENGHVRISDLGLACDF--SKKKPHASVGTHGYMAPEVLMKGQAYDSSAD 9
>09007
          Length = 1440

 Score = 63.9 bits (154), Expect = 7e-11,   Method: Compositional matrix adjust.
 Identities = 63/289 (21%), Positives = 128/289 (44%), Gaps = 16/289 (5%)
 Frame = -1

Query: 8   EKIGEGTYGTV----FKAKNRETHEIVA--LKRVRLDDDDEGVPSSALREICLLKELKHK 61
           + +G+G +GTV    + A++ E  ++    L + ++  D +      L+E  +++ L H+
Sbjct: 861 KSLGQGHFGTVRQAIWTAESGEKVQVAVKCLSKDKIHKDGQ----EFLKETAIMQMLDHE 694

Query: 62  NIVRLHD-VLHSDKKLTLVFEFCD-QDLKKYFDSCNGDLDPEIVK--SFLFQLLKGLGFC 117
           NIVR++  V+ +   + LV E    + L +     +  +D  + +   F  Q+  G+ + 
Sbjct: 693 NIVRVYGVVMDNGADIMLVTELAPMRSLLECVKEVSARVDFSVPRLCDFSQQVCDGMSYL 514

Query: 118 HSRNVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVRCYSAEVV------TLWYRPPD 171
            S+ ++HRDL  +N+L+    ++K++D G++ A G     Y ++          W  P  
Sbjct: 513 ESKRLVHRDLAARNILLFSKSKVKISDVGVSGALGAGKEYYQSQQTIHLQNAVAWCAPES 334

Query: 172 VLFGAKLYSTSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQWPAMT 231
             F    +S++ D+W+ G +  E    G    P   ++ Q  +I   +  P  ++     
Sbjct: 333 --FRNLCFSSASDVWAFGVLLWEFFTHG--FQPWAGLNGQ--QIMEAVDAPQSQR----L 184

Query: 232 KLPDYKPYPMYPATTSLVNVVPKLNATGRDLLQNLLKCNPVQRISAEEA 280
           + PD  P   Y          P+   T   L   L +  P+Q  + ++A
Sbjct: 183 EQPDLCPKEYYAVMLKCWEQEPQRRPTFSQLFLTLPQIRPIQVKAVKDA 37
>18287
          Length = 678

 Score = 63.5 bits (153), Expect = 9e-11,   Method: Compositional matrix adjust.
 Identities = 45/114 (39%), Positives = 54/114 (47%), Gaps = 4/114 (3%)
 Frame = -3

Query: 179 YSTSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQWPAMTKLPDY-- 236
           Y  SID+WS GCIFAEL  + R LF       QL  I  L+GTP  E      +      
Sbjct: 673 YDYSIDIWSVGCIFAELL-SRRILFQAQGPVQQLDMIINLVGTPRPEDMERACEGARNHI 497

Query: 237 --KPYPMYPATTSLVNVVPKLNATGRDLLQNLLKCNPVQRISAEEALQHPYFSD 288
             +P+      T L N+ P        LL  +L  NP  RISAEEAL HPY  +
Sbjct: 496 LNQPFRRQNLLT-LYNLSPHATHEAVRLLTRMLILNPKNRISAEEALSHPYLDE 338
>19301
          Length = 712

 Score = 63.5 bits (153), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 41/142 (28%), Positives = 69/142 (48%)
 Frame = +2

Query: 7   LEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKHKNIVRL 66
           LE +G G  G VF  K     E VA+K+VR       +  + +R    L++L H NI+  
Sbjct: 320 LEWLGSGAQGAVFLGK--LCAEEVAVKKVR------DIKETDIRN---LRKLNHPNIISF 466

Query: 67  HDVLHSDKKLTLVFEFCDQDLKKYFDSCNGDLDPEIVKSFLFQLLKGLGFCHSRNVLHRD 126
             V        ++ E+C             ++ P +V  +  Q+  G+ + HS  ++HRD
Sbjct: 467 KGVCTQAPCYCIIMEYCPYGQLYEVLRDGKEIPPALVLDWSKQIASGMNYLHSHKIIHRD 646

Query: 127 LKPQNLLINRNGELKLADFGLA 148
           LK  N+L+ +N  +K++DFG +
Sbjct: 647 LKSPNVLVAKNDVVKISDFGTS 712
>11780
          Length = 1713

 Score = 63.5 bits (153), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 53/156 (33%), Positives = 86/156 (55%), Gaps = 5/156 (3%)
 Frame = +3

Query: 2   QKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKHK 61
           Q  E  E IG+G +G V+K   R   + VA+K+  L D D G   S L+E  ++  L+H 
Sbjct: 597 QDLEIGEAIGKGDFGDVYKGMYR--GQPVAIKQ--LKDKDRG-EQSFLQEASVMTSLRHD 761

Query: 62  NIVRLHDVLHSDKKLTLVFEFCDQ-DLKKYFDSCNGDLDPEIVK----SFLFQLLKGLGF 116
           N+VRL  V+  +  + LV EF  + +L +Y  S    +   I K    +F       + +
Sbjct: 762 NLVRLIGVVLGET-IFLVTEFMGKGNLVEYLRSRGRSV---ITKKDQINFATDTCAAMEY 929

Query: 117 CHSRNVLHRDLKPQNLLINRNGELKLADFGLARAFG 152
             S+ ++HRDL  +N+L++ +G+ K++DFGLA+ FG
Sbjct: 930 LESKRLVHRDLAARNVLVHDDGKAKVSDFGLAK-FG 1034
>00392
          Length = 668

 Score = 62.8 bits (151), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 51/171 (29%), Positives = 88/171 (51%), Gaps = 9/171 (5%)
 Frame = +3

Query: 54  LLKELKHKNIVRLHDVL----HSDKK-LTLVFEFCDQDLKKYFDSCNGDLDPEIVKSFLF 108
           +LKEL+H NIVR  D      H ++K + LV E       K +       + +I+K++  
Sbjct: 90  MLKELQHPNIVRFFDYWEEHNHRNRKVIILVTELMTSGTLKTYLKRFKKPNVKILKNWCR 269

Query: 109 QLLKGLGFCHSRN--VLHRDLKPQNLLINR-NGELKLADFGLARAFGIPVRCYSAEVV-T 164
           Q+LKGL F H+R   V+HRDLK  N+ I    G +K+ D GLA    +  + ++  V+ T
Sbjct: 270 QVLKGLYFLHTRTPPVIHRDLKCDNIFITGPTGSVKIGDLGLA---TLKNQSFAKSVIGT 440

Query: 165 LWYRPPDVLFGAKLYSTSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRI 215
             +  P++    + Y  ++D+++ G    E+A++  P    ++     KR+
Sbjct: 441 PEFMAPEMY--EEHYDEAVDVYAFGMCMLEMASSEYPYSECSNAAQIYKRV 587
>19094
          Length = 898

 Score = 61.6 bits (148), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 34/98 (34%), Positives = 52/98 (53%), Gaps = 2/98 (2%)
 Frame = +1

Query: 103 VKSFLFQLLKGLGFCHSRNVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVRCYSAEV 162
           + + L+  LKGL + HSR  +HRD+K  N+L+N  G  KLADFG+A      +   +  +
Sbjct: 64  IATILYYTLKGL*YLHSRRKIHRDIKAGNILLNNEGHAKLADFGVAGQLTDTMAKRNTVI 243

Query: 163 VTLWYRPPDVL--FGAKLYSTSIDMWSAGCIFAELANA 198
            T ++  P+V+   G   Y    D+WS G    E+A  
Sbjct: 244 GTPYWMAPEVIQEIG---YDCVADIWSLGITALEMAEG 348
>16003
          Length = 926

 Score = 61.6 bits (148), Expect = 4e-10,   Method: Compositional matrix adjust.
 Identities = 37/88 (42%), Positives = 51/88 (57%)
 Frame = -1

Query: 201 PLFPGNDVDDQLKRIFRLLGTPTEEQWPAMTKLPDYKPYPMYPATTSLVNVVPKLNATGR 260
           P  PG+   DQL +IF +LGTPTE +WPA+T LPDY  +  +     L  +         
Sbjct: 911 PFLPGDTDLDQLGKIFNMLGTPTETEWPAVTSLPDYIQF-KHCQKQPLKEIFTAAGDDLL 735

Query: 261 DLLQNLLKCNPVQRISAEEALQHPYFSD 288
           +LL  LL  NP+ R +A +AL+ PYFS+
Sbjct: 734 ELLDKLLAMNPLHRCTATQALKMPYFSN 651
>30755
          Length = 1137

 Score = 61.2 bits (147), Expect = 5e-10,   Method: Compositional matrix adjust.
 Identities = 30/95 (31%), Positives = 52/95 (54%)
 Frame = +2

Query: 109 QLLKGLGFCHSRNVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYR 168
           +++  LG+ HS+ +++RDLK +NLL++++G +K+ADFGL +      R       T  Y 
Sbjct: 56  EIISALGYLHSQGIIYRDLKLENLLLDKDGHIKVADFGLCKEDITYGRTTKTFCGTPEYL 235

Query: 169 PPDVLFGAKLYSTSIDMWSAGCIFAELANAGRPLF 203
            P+VL     Y  ++D W  G +  E+     P +
Sbjct: 236 APEVL-DDNDYGRAVDWWGTGVVMYEMICGRLPFY 337
>07940
          Length = 1336

 Score = 61.2 bits (147), Expect = 5e-10,   Method: Compositional matrix adjust.
 Identities = 36/116 (31%), Positives = 60/116 (51%), Gaps = 3/116 (2%)
 Frame = -3

Query: 98  LDPEIVKSFLFQLLKGLGFCHSRNVLHRDLKPQNLLINRNGELKLADFGLAR---AFGIP 154
           L P+ + S+ +Q+ +G+ +  S+  +HRDL  +N+L+     LK+ADFGL R    F   
Sbjct: 356 LTPKDLISYAYQVARGMEYLASKQCIHRDLAARNVLVAEEYVLKIADFGLTRNLQQFDYY 177

Query: 155 VRCYSAEVVTLWYRPPDVLFGAKLYSTSIDMWSAGCIFAELANAGRPLFPGNDVDD 210
            +     +   W   P+ LF  K Y++  D+WS G +  E+   G   +P   V+D
Sbjct: 176 RKTTDGRLPVKWM-APEALFDRK-YTSKSDVWSYGVLLWEIFTLGGNPYPSVPVED 15
>32359
          Length = 928

 Score = 54.3 bits (129), Expect(2) = 9e-10,   Method: Compositional matrix adjust.
 Identities = 36/126 (28%), Positives = 70/126 (55%), Gaps = 9/126 (7%)
 Frame = -1

Query: 4   YEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKHKNI 63
           Y   + IG G++G V++AK  +T E+VA+K+V  D   +       RE+ ++++L+H+NI
Sbjct: 424 YTDAKVIGNGSFGVVYQAKLVDTSELVAIKKVLQDKRFKN------RELQIMRKLEHQNI 263

Query: 64  VRLHDVLHS--DKK----LTLVFEFCDQD---LKKYFDSCNGDLDPEIVKSFLFQLLKGL 114
           V+L    +S  +KK    L LV E+  +    + +++      +    +K +++QL + L
Sbjct: 262 VKLKFFFYSSGEKKDEVFLNLVLEYVPETVYRVARHYSKSKQTIPILYIKLYMYQLFRSL 83

Query: 115 GFCHSR 120
            + HS+
Sbjct: 82  AYIHSQ 65

 Score = 25.8 bits (55), Expect(2) = 9e-10,   Method: Compositional matrix adjust.
 Identities = 10/14 (71%), Positives = 13/14 (92%)
 Frame = -3

Query: 122 VLHRDLKPQNLLIN 135
           V HRD+KPQNLL++
Sbjct: 62  VCHRDIKPQNLLLD 21
>18484
          Length = 635

 Score = 60.1 bits (144), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 34/121 (28%), Positives = 60/121 (49%)
 Frame = +1

Query: 95  NGDLDPEIVKSFLFQLLKGLGFCHSRNVLHRDLKPQNLLINRNGELKLADFGLARAFGIP 154
            G     +   +  ++  GL F H + +++RDLK  N++++  G +K+ADFG+ +     
Sbjct: 25  EGKFKEPVAAFYAAEIAVGLFFLHDQGIIYRDLKLDNVMLDSEGHIKIADFGMCKEGMTG 204

Query: 155 VRCYSAEVVTLWYRPPDVLFGAKLYSTSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKR 214
                    T  Y  P+++   + YS S+D W+ G +  E+  AG+P F G D D+    
Sbjct: 205 DATTRTFCGTPDYIAPEIVL-YQPYSKSVDWWAYGVLLFEML-AGQPPFDGEDEDELFSS 378

Query: 215 I 215
           I
Sbjct: 379 I 381
>14477
          Length = 493

 Score = 58.9 bits (141), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 43/155 (27%), Positives = 78/155 (50%), Gaps = 2/155 (1%)
 Frame = -1

Query: 9   KIGEGTYGTVFKAKNR-ETHEI-VALKRVRLDDDDEGVPSSALREICLLKELKHKNIVRL 66
           K+G G +G+V K   R +  EI VA+K ++  D D  V S  ++E  ++K++ H +IVRL
Sbjct: 469 KLGAGNFGSVMKGVCRLDDREIPVAIKVLKNADLDPSVQSELIKEAEVMKKMDHMHIVRL 290

Query: 67  HDVLHSDKKLTLVFEFCDQDLKKYFDSCNGDLDPEIVKSFLFQLLKGLGFCHSRNVLHRD 126
             +   +  + LV E         F   N  L    +   ++Q+ +G+ +  +   +HRD
Sbjct: 289 IGLCEGET-MMLVLELAKLGPLNKFLPKNKHLPLWNILELMWQVSQGMEYLEANKFVHRD 113

Query: 127 LKPQNLLINRNGELKLADFGLARAFGIPVRCYSAE 161
           L  +N+L+      K++DFG+++        Y A+
Sbjct: 112 LAARNILLCDEHFAKISDFGMSKTLSRENNYYMAQ 8
>00715
          Length = 1788

 Score = 58.5 bits (140), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 56/209 (26%), Positives = 93/209 (44%), Gaps = 45/209 (21%)
 Frame = +1

Query: 58  LKHKNIVRLHDV--LHS-DKKLTLVFEFCDQ-DLKKYFDSCNGDLDPEIVKSFLFQLLKG 113
           L+H N+V +     LH  +    L  E+    +L+   +    D+D  +  S   Q+ +G
Sbjct: 97  LRHVNVVSILGATSLHRFEDGAWLAMEYVGPLNLQTILNDHQQDIDSSMRLSLALQMARG 276

Query: 114 LGFCHSRNVLHRDLKPQNLLINRNGELKLADFGLA------------RAFGI-------- 153
           L + HS N++H DLKP N L+ R+ +L++ADFG              R  G+        
Sbjct: 277 LHYLHSINIVHLDLKPANCLLTRDLKLRIADFGCCHQLTPTGLDMGEREGGMAGNELELT 456

Query: 154 PVR-CYSAEVV-TLWYRPPDVLFG------AKLYSTSIDMW-------------SAGCIF 192
           PV+  +  E+  TL YR P++L G      + +YS  I +W             +   ++
Sbjct: 457 PVQGAWKNELAGTLAYRAPELLKGLQPSVRSDVYSLGITLWQMCTRQGPYEGVPAHAVVY 636

Query: 193 AELANAGRPLFPGNDVDDQLKRIFRLLGT 221
             ++   RP  P +  DD  + +FR L T
Sbjct: 637 QVVSKDLRPCPPPSTEDDPFEVMFRDLYT 723
>13212
          Length = 1067

 Score = 56.6 bits (135), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 34/119 (28%), Positives = 57/119 (47%), Gaps = 8/119 (6%)
 Frame = -1

Query: 91   FDSCNGDLDPEIVKSFL----FQLLKGLGFCHSRNVLHRDLKPQNLLINRNGELKLADFG 146
             DS   DL+  + ++ +     ++   L F H  +V+HRD+K  N+L+  +GE+KLADFG
Sbjct: 1022 LDSIMVDLEKPMTEAQICYVCHEMCMALDFLHRHHVIHRDIKAGNVLLTIDGEVKLADFG 843

Query: 147  LARAFGIPVRCYSAEVVTLWYRPPDVLFGAKL----YSTSIDMWSAGCIFAELANAGRP 201
            ++       +     + T ++  P+V+    L    Y    D+WS G    E A    P
Sbjct: 842  VSAKNTQTQQKRDTFIGTPYWMAPEVVLCETLKDTPYDFKADIWSLGVTLIEFAQIEPP 666
>21079
          Length = 878

 Score = 56.6 bits (135), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 44/147 (29%), Positives = 73/147 (49%), Gaps = 5/147 (3%)
 Frame = +1

Query: 60  HKNIVRLHDVLHSDKKLTLVFEFCDQDLKKYFDSCNGD---LDPEIVKSFLFQLLKGLGF 116
           H  ++ L D   + + + LV EF      + F+    D   L       F+ Q+  G+G+
Sbjct: 1   HPKLLMLWDAFEAPRTMVLVMEFVGA--GELFERVIRDDFVLTERDCVHFVRQICSGVGY 174

Query: 117 CHSRNVLHRDLKPQNLLI--NRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLF 174
            H++++LH DLKP+N+L   + + ++K+ DFGLAR F  P         T  +  P+V+ 
Sbjct: 175 MHTQSILHLDLKPENVLCVSDNSNQIKIIDFGLAR-FYKPGDSLQVLFGTPEFIAPEVVN 351

Query: 175 GAKLYSTSIDMWSAGCIFAELANAGRP 201
             ++  T+ DMWS G I   L +   P
Sbjct: 352 YDEINFTT-DMWSIGVICYILLSGLSP 429
>14116
          Length = 1017

 Score = 56.2 bits (134), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 54/210 (25%), Positives = 95/210 (45%), Gaps = 13/210 (6%)
 Frame = -1

Query: 8   EKIGEGTYGTVFKA----KNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKHKNI 63
           E+IG+G +G V +       ++   +VA+K +  ++  E    S L+E  ++K+  H N+
Sbjct: 618 EEIGKGNFGCVKRGFLTLPEQKGDILVAVKTLHNNNPREIELQSFLQEALIMKDFHHSNV 439

Query: 64  VRLHDV-LHSDKKLTLVFEFCDQ-DLKKYFDSCNGDLDPEIVKSFLF--QLLKGLGFCHS 119
           + L  + L+ D    +V  F    DL  Y    +    P I    ++   + +G+ +   
Sbjct: 438 LTLIGICLNLDDMPLVVLPFMKHGDLLTYIR--DDQHQPTIKDLIMYGVDIARGMDYLAG 265

Query: 120 RNVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVRCYSAE-----VVTLWYRPPDVLF 174
              +HRDL  +N +++ +  +K+ADFGLAR        YS+E     +   W     +  
Sbjct: 264 LKFVHRDLAARNCMLDEDFHVKVADFGLARDI-YEKEYYSSENKKAKLPVKWMALESLEK 88

Query: 175 GAKLYSTSIDMWSAGCIFAELANAGRPLFP 204
           G   Y +  D+WS G +  EL   G    P
Sbjct: 87  GN--YDSKTDVWSYGVVLWELLTRGSDALP 4
>11185
          Length = 473

 Score = 55.8 bits (133), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 36/120 (30%), Positives = 56/120 (46%), Gaps = 22/120 (18%)
 Frame = +1

Query: 103 VKSFLFQLLKGLGFCHSRNVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVR---CYS 159
           ++ F   L+ GL + HS  +L  DL+P  +L++ +G LK ADFGL++  G  +       
Sbjct: 7   IRDFGIHLVTGLHYIHSLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKF 186

Query: 160 AEVVTLW-------------------YRPPDVLFGAKLYSTSIDMWSAGCIFAELANAGR 200
           AE    W                   Y  P+V  GA+  S   D+W+ GC+F E+ +  R
Sbjct: 187 AEAGDQWNIQSAEEMMKQVPTSGSPTYMAPEVFQGAE-PSIMSDLWALGCVFYEMFSGSR 363
>26909
          Length = 394

 Score = 55.8 bits (133), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 37/114 (32%), Positives = 58/114 (50%), Gaps = 18/114 (15%)
 Frame = +2

Query: 191 IFAELANAGRPLFPGNDVD---------DQLKRIFRLLGTPTEEQWPAMTKLPDYKPYPM 241
           IFAEL  +  P+F     D         DQL RIF ++G P E+ W  + ++P+++    
Sbjct: 2   IFAELLTS-EPIFHCRQEDIKTSNPYHHDQLDRIFNVMGFPQEKDWEDIRRMPEHQQLTK 178

Query: 242 YPATTSLVNV---------VPKLNATGRDLLQNLLKCNPVQRISAEEALQHPYF 286
               +S VN            K ++    LLQ LL  +PV+RI++E+A++ PYF
Sbjct: 179 DFKRSSYVNCNLMKYMEKHKVKADSKAFHLLQKLLTMDPVKRITSEQAMKDPYF 340
>31885
          Length = 529

 Score = 52.0 bits (123), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 44/155 (28%), Positives = 67/155 (43%), Gaps = 6/155 (3%)
 Frame = -2

Query: 54  LLKELKHKNIVRLHDVLHSDKKLTLVFE-FCDQDLKKYFDSCNGDLDPEIVKSFLFQLLK 112
           +L  L H  +V L      ++ L +V + F   DL+ Y          + VK +L QL  
Sbjct: 513 MLTRLDHPFLVNLWYAFQDEEDLFMVVDLFLGGDLR-YHMQQEVSFREDCVKFYLCQLAL 337

Query: 113 GLGFCHSRNVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDV 172
            L +  S+ ++HRD+KP N+L++  G   + DF +A          S    T  Y  P+V
Sbjct: 336 VLDYLRSQKIVHRDIKPDNILLDEQGHCHVTDFNIATQLEDDELATSTS-GTRPYMAPEV 160

Query: 173 LFGAKL-----YSTSIDMWSAGCIFAELANAGRPL 202
            +G  +     Y   +D WS G    EL    RP 
Sbjct: 159 -YGVAINERRGYGFPVDWWSLGVSLFELLKKRRPF 58
>17253
          Length = 483

 Score = 50.8 bits (120), Expect = 6e-07,   Method: Compositional matrix adjust.
 Identities = 31/120 (25%), Positives = 54/120 (45%), Gaps = 13/120 (10%)
 Frame = -1

Query: 46  SSALREICLLKEL-KHKNIVRLHDVLHSDKKLTLVFEFCDQ------------DLKKYFD 92
           S  LRE+ ++++L +H N+V             ++ EFC              D   +  
Sbjct: 414 SEFLRELSIMRKLPRHPNVVSFMGCCTMSDPALILMEFCCHGDLLSFLRKRRPDRTVFLT 235

Query: 93  SCNGDLDPEIVKSFLFQLLKGLGFCHSRNVLHRDLKPQNLLINRNGELKLADFGLARAFG 152
           S   DL      SF   + +G+    +  ++HRD+  +N+LI+     K++DFGL+R  G
Sbjct: 234 STANDLTARDFFSFALHVARGMAHVANNKIVHRDVAARNVLISERNVCKVSDFGLSRRVG 55
>26711
          Length = 405

 Score = 49.7 bits (117), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 35/108 (32%), Positives = 56/108 (51%), Gaps = 2/108 (1%)
 Frame = -2

Query: 109 QLLKGLGFCHSRNVLHRDLKPQNLLINRN--GELKLADFGLARAFGIPVRCYSAEVVTLW 166
           Q+L  L   H++ V+H DLKP NLL++ +    ++L DFGLAR    P   +     T  
Sbjct: 392 QVLDILQHVHAQGVVHMDLKPSNLLLSGDKLDSVQLIDFGLARKLYPPQETFLNH-GTPG 216

Query: 167 YRPPDVLFGAKLYSTSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKR 214
           +  P+ L   K  ST+ D+W  G + A +  +G+  F  +   + LK+
Sbjct: 215 FTSPEAL-DVKPISTASDVWGVG-VLAYILLSGQSPFQADSATESLKK 78
>18401
          Length = 463

 Score = 49.3 bits (116), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 43/148 (29%), Positives = 65/148 (43%), Gaps = 16/148 (10%)
 Frame = -3

Query: 158 YSAEVVTLWYRPPDVLFGAKLYSTSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFR 217
           +S  V T  YR P+V+     +S   D+WS GCI  EL   G  LF  +D  + L  + R
Sbjct: 461 HSTIVSTRHYRAPEVILELG-WSHPCDVWSVGCIMFELY-TGYTLFQTHDNKEHLAMMER 288

Query: 218 LLGT-------PTEEQ---------WPAMTKLPDYKPYPMYPATTSLVNVVPKLNATGRD 261
           +LG+        T++Q          P  + +  Y      P    + +   K +    D
Sbjct: 287 ILGSLPYRMAKKTKKQKYFHHGRLDVPERSSMARYVRENTKPLLRYVKDRENKDHQQLFD 108

Query: 262 LLQNLLKCNPVQRISAEEALQHPYFSDF 289
           L++ LL      R S  +ALQHP+FS +
Sbjct: 107 LMKKLLAYEASSRYSLLQALQHPFFSPY 24
>16708
          Length = 1397

 Score = 49.3 bits (116), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 46/193 (23%), Positives = 84/193 (43%), Gaps = 15/193 (7%)
 Frame = -1

Query: 7    LEKIGEGTYGTVFKAKNRETHEIVALKRVRL--DDDDEGVPSSALREICLLKELKHKNIV 64
            L+ +G+G +G V++A+   THE  ALK   L     DE      +     L ++    + 
Sbjct: 1388 LQVLGKGVFGKVYEARLLSTHEKAALKTSILCHHSLDEVEALGRIEGGFYLAQMFGAWVT 1209

Query: 65   RLHDVLHSDKKLTLVFEFCDQD--LKKYFDSCNGDL-----DPEIVKSFLFQLLKGLGFC 117
             L        K+ ++  F +       Y    N ++     +P +V     Q +  L   
Sbjct: 1208 CL-----PFPKMNILLHFYEMGPLCNVYAHYKNKEMPIRWSNPAMVCCIAGQXVCALEHI 1044

Query: 118  HSRNVLHRDLKPQNLLINRNGELKLADFGLARAFGI---PVRCYSAEVV---TLWYRPPD 171
            H   V+H D+K  N+L++ +G  KL D+G+A+ + +   P   +S+      T + RPP 
Sbjct: 1043 HELGVVHMDVKADNVLVDAHGNCKLTDYGIAQLYKVYPAPTETHSSGCTNKRTFYTRPPA 864

Query: 172  VLFGAKLYSTSID 184
             +  ++ +S   D
Sbjct: 863  TMTPSERFSEEGD 825
>37602
          Length = 804

 Score = 48.1 bits (113), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 24/72 (33%), Positives = 37/72 (51%)
 Frame = -1

Query: 74  KKLTLVFEFCDQDLKKYFDSCNGDLDPEIVKSFLFQLLKGLGFCHSRNVLHRDLKPQNLL 133
           +KL +  E+C     +      G L    +     + LKGL + H R  +HRD+K  N+L
Sbjct: 300 EKLWIAMEYCGGGSMQDIYHVTGPLTEPQIAFVCRETLKGLHYLHRRGKMHRDIKGANIL 121

Query: 134 INRNGELKLADF 145
           +   G++KLADF
Sbjct: 120 LTEEGDVKLADF 85

 Score = 28.9 bits (63), Expect = 2.4,   Method: Compositional matrix adjust.
 Identities = 10/22 (45%), Positives = 17/22 (77%)
 Frame = -2

Query: 1   MQKYEKLEKIGEGTYGTVFKAK 22
           +  +E ++++G GTYG V+KAK
Sbjct: 512 LDDFELIQRVGSGTYGDVYKAK 447
>07291
          Length = 833

 Score = 48.1 bits (113), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 39/159 (24%), Positives = 69/159 (43%), Gaps = 10/159 (6%)
 Frame = +1

Query: 106 FLFQLLKGLGFCHSRNVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVRCYSAE---- 161
           F  Q+  G+ +     V+HR+L  +N ++  +G L+L+D+G+  +   P   Y+A+    
Sbjct: 64  FGRQIADGMAYLQEVKVVHRNLAARNCIVTEDGRLQLSDYGVTGSL-FPQSYYTADDSPA 240

Query: 162 -VVTLWYRPPDVLFGAKLYSTSIDMWSAGCIFAELANAGRPLFPGNDVDDQ-----LKRI 215
             +  W  P  +      +S+  D+W+ G +  EL   G   +P  DV++      LK  
Sbjct: 241 RDLVKWMAPETI--DNFHFSSKSDVWAFGVVLWELLTRGITPYP--DVENSSLLPYLKEG 408

Query: 216 FRLLGTPTEEQWPAMTKLPDYKPYPMYPATTSLVNVVPK 254
            R+             K P   P P+Y   T+  N  P+
Sbjct: 409 HRM-------------KKPKQSPEPVYEMMTACWNESPE 486
>01392
          Length = 1806

 Score = 46.6 bits (109), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 49/196 (25%), Positives = 83/196 (42%), Gaps = 12/196 (6%)
 Frame = -1

Query: 109  QLLKGLGFCHSRNVLHRDLKPQNLLINRNGE---LKLADFGLARAF-----GIPVRCYSA 160
             + + L F HS+ + HRDLKP+N+L     +   +K+ DF LA        G        
Sbjct: 1767 HIARALDFLHSKGIAHRDLKPENILCEHLDDVVPVKICDFDLASGISCDGDGTKTPELLT 1588

Query: 161  EVVTLWYRPPDVL---FGAKL-YSTSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIF 216
             V +  Y  P+V+    G    Y    D+WS G I   +   G P F G   +D      
Sbjct: 1587 PVGSAEYMAPEVVDAWVGDSFSYDKRCDLWSLGIILYIML-CGYPPFYGQCGEDCGWNRG 1411

Query: 217  RLLGTPTEEQWPAMTKLPDYKPYPMYPATTSLVNVVPKLNATGRDLLQNLLKCNPVQRIS 276
                   +  + ++     +  +P    T+        ++++ +DL+++LL   P +R S
Sbjct: 1410 EACHDCQDMLFNSIQD--GHYKFPSQEWTS--------ISSSAKDLIRHLLVREPRKRYS 1261

Query: 277  AEEALQHPYFSDFCPP 292
            A + L+HP+    C P
Sbjct: 1260 AADVLKHPW---ICTP 1222
>17300
          Length = 480

 Score = 46.6 bits (109), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 34/126 (26%), Positives = 58/126 (46%), Gaps = 17/126 (13%)
 Frame = +1

Query: 110 LLKGLGFCHSRNVLHRDLKPQNLLINRNGELKLADFGLARAF--------------GIPV 155
           +  G+G       +HRDL  +N+L+N     K+ADFGL+R                 IPV
Sbjct: 1   ISSGMGXLADMGYVHRDLAARNILVNEILVCKVADFGLSREIESDTTEGAYTTKGGKIPV 180

Query: 156 RCYSAEVVTLWYRPPDVLFGAKLYSTSIDMWSAGCIFAELANAG-RPL--FPGNDVDDQL 212
           R         W  P  + +  + ++++ D+WS G +  E+ + G RP   +   DV   +
Sbjct: 181 R---------WTAPEAIAY--RKFTSASDVWSFGVVMWEVMSYGERPYWNWSNQDVIKAV 327

Query: 213 KRIFRL 218
           ++ +RL
Sbjct: 328 EKGYRL 345
>01106
          Length = 878

 Score = 45.4 bits (106), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 41/146 (28%), Positives = 71/146 (48%), Gaps = 14/146 (9%)
 Frame = +3

Query: 3   KYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKHKN 62
           +Y  + K+G G + TV+   +      VALK V+     +    +AL E+ LLK ++  +
Sbjct: 321 RYHVIRKLGWGHFSTVWLCWDLTCKRFVALKVVK---SAQHYTETALDEVKLLKCVRESD 491

Query: 63  I--------VRLHDVLH----SDKKLTLVFEFCDQDLKKYFDSCNGDLDP-EIVKSFLFQ 109
           +        V+L D       +   + +VFE    +L K     N    P   VK  + Q
Sbjct: 492 VADPARAKCVQLLDDFKISGVNGTHVAMVFEVLGYNLLKLIIRSNYQGIPIHNVKLIIRQ 671

Query: 110 LLKGLGFCHSR-NVLHRDLKPQNLLI 134
           +L+GL + H++  ++H D+KP+N+LI
Sbjct: 672 VLEGLSYMHAKCRIIHTDIKPENILI 749
>22005
          Length = 873

 Score = 45.1 bits (105), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 53/242 (21%), Positives = 92/242 (38%), Gaps = 56/242 (23%)
 Frame = +1

Query: 10  IGEGTYGTVFKAKNRETHEIVA----------LKRVRLDDDDEGVPSSALREICLLKELK 59
           IG+G +G V K K      +V           L ++  +D  E + S   RE  L+ +  
Sbjct: 7   IGQGAFGRVSKLKFLGLASLVGELIPEKRP*LL*KMLKEDASEDLQSDFEREASLMADFD 186

Query: 60  HKNIVRLHDVLHSDKKLTLVFEF------------------------------------- 82
           H NIV+L  V    K + L+FEF                                     
Sbjct: 187 HPNIVKLLGVCAIGKPMCLLFEFMSKGDLNDFLRLCSPENYNLPVSRSQNLVVDLEDGLR 366

Query: 83  -------CDQDLKKYFDSCNGDLDPEIVKSFLFQLLKGLGFCHSRNVLHRDLKPQNLLIN 135
                  C++D +     C+G L  +       Q+  G+ +   ++ +HRDL  + +   
Sbjct: 367 VEVEAEECEKDTQSEDRDCSGMLXTKDQLYISQQISAGMAYLAQKDYVHRDLATRTVXSR 546

Query: 136 RNGELKLADFGLARAFGIP--VRCYSAEVVTLWYRPPDVLFGAKLYSTSIDMWSAGCIFA 193
                 ++DFGLAR+       R    + + + + P + +  +K +ST  D+WS G +  
Sbjct: 547 TT-*S*ISDFGLARSVHSVDYYRGSEQDAIPIRWMPLEAILYSK-FSTQSDVWSFGVVLW 720

Query: 194 EL 195
           E+
Sbjct: 721 EI 726
>00638
          Length = 1595

 Score = 44.3 bits (103), Expect = 7e-05,   Method: Compositional matrix adjust.
 Identities = 29/89 (32%), Positives = 51/89 (57%), Gaps = 4/89 (4%)
 Frame = +2

Query: 51  EICLLKELKH-KNIVRLHDVLHSDKKLT--LVFEFCDQ-DLKKYFDSCNGDLDPEIVKSF 106
           EI +L+ L+   N++ L  ++      T  L+FE  +  D K+ + +   D D   ++ +
Sbjct: 266 EIKILENLRGGTNVITLLAIVKDPVSRTPALIFEHVNNTDFKQLYQTFT-DYD---IRFY 433

Query: 107 LFQLLKGLGFCHSRNVLHRDLKPQNLLIN 135
           L++L+K L FCHS  ++HRD+KP   L+N
Sbjct: 434 LYELMKALDFCHSMGIMHRDVKPSPPLVN 520
>12786
          Length = 460

 Score = 43.9 bits (102), Expect = 7e-05,   Method: Compositional matrix adjust.
 Identities = 33/126 (26%), Positives = 51/126 (40%), Gaps = 21/126 (16%)
 Frame = -3

Query: 98  LDPEIVKSFLFQLLKGLGFCHSRNVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVRC 157
           LD  ++K +  ++L+ +   H+  V+H DLKP N ++   G LKL DFG+A         
Sbjct: 419 LDRMMIKFYWREMLRAVKALHNEGVIHSDLKPANFML-VAGNLKLIDFGIANTLQQDKTS 243

Query: 158 Y--SAEVVTLWYRPPDVLFGA-----------------KLYSTSI--DMWSAGCIFAELA 196
               + V T  Y  P+ +  A                   Y   +  D+WS GCI   + 
Sbjct: 242 VLKDSRVGTPSYMSPEAIMAACDDSADDSMEEDGHRTKPKYKVGVRSDVWSLGCILYNMV 63

Query: 197 NAGRPL 202
               P 
Sbjct: 62  YGRTPF 45
>28157
          Length = 400

 Score = 43.9 bits (102), Expect = 8e-05,   Method: Compositional matrix adjust.
 Identities = 38/128 (29%), Positives = 66/128 (51%), Gaps = 9/128 (7%)
 Frame = +3

Query: 30  VALKRVRLDDDDEGVPSSALREICLLKELKHKNIVRLHDVLHSDKKLTLVFEFCDQDLKK 89
           VA+KR+  + + +    S ++E+  L  + H NIV L+     D  + LV E+ +     
Sbjct: 9   VAVKRIESEQEKK----SFMQELKQLSRVSHPNIVCLYGAC-RDHPVCLVMEYAEGG--S 167

Query: 90  YFDSCNGDL-DPEIVKS----FLFQLLKGLGFCHS---RNVLHRDLKPQNLLINRNG-EL 140
            ++  +G    P+   +    +L Q   G+ + H    + ++HRDLKP NLL+ + G +L
Sbjct: 168 LYNVLHGSGPQPQYTAAHAMNWLLQCALGVEYLHGMKPKALIHRDLKPPNLLLIQCGTKL 347

Query: 141 KLADFGLA 148
           K+ DFG A
Sbjct: 348 KICDFGTA 371
>06358
          Length = 1517

 Score = 43.1 bits (100), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 71/321 (22%), Positives = 118/321 (36%), Gaps = 36/321 (11%)
 Frame = +3

Query: 4   YEKLEKIGEGTYGTVFKAKNRETHE---IVALKRVRLDD----DDEGVPSSALREICLLK 56
           Y ++   G G    VF A  + T E   +   ++  +D     D E +       +  L 
Sbjct: 12  YNQVASAGPGLLWKVFAASKKSTKEEASVFVFEKKSVDRYSRRDREAIVEVLRVGVQQLT 191

Query: 57  ELKHKNIVRLHDVLHSDKKLTLVFEFCDQDLKKYFDSCNGDL----------------DP 100
           +L+H  I+ + + L   ++      F  + +     +  GDL                D 
Sbjct: 192 KLRHPKILAVINPLEESRE---TLAFATEPVFASLANVLGDLSSIXTVPKELQDYQLYDV 362

Query: 101 EIVKSFLFQLLKGLGFCHS-RNVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVRCYS 159
           EI K  L Q+ + LGF H+   ++HR++ P+ +++ + G  KLA +        P     
Sbjct: 363 EI-KHGLLQVTEALGFLHNDAKMMHRNVCPEAIMLTKLGSWKLAGYEFCVRSSDPQSTDP 539

Query: 160 AEVVTLW------YRPPDVLFGAKLY------STSIDMWSAGCIFAELANAGRPLFPGND 207
           +     W         P + F A  Y       T  DM+S G +   +   G+PLF  N 
Sbjct: 540 SYPFYEWRSDIAPVTQPHLDFMAPEYVLTMQCGTGSDMFSLGLLVYSVFAKGKPLFECNG 719

Query: 208 VDDQLKRIFRLLGTPTEEQWPAMTKLPDYKPYPMYPATTSLVNVVPKLNATGRDLLQNLL 267
                K       +  EE               +     SL+ VVP+     RD ++ LL
Sbjct: 720 ELSAFK-------SNAEE---------------LRHMRVSLLGVVPE---DLRDHVKLLL 824

Query: 268 KCNPVQRISAEEALQHPYFSD 288
              P  R  A +  + P+F D
Sbjct: 825 NIEPAVRPDAAQLSKVPFFED 887
>20640
          Length = 1492

 Score = 42.7 bits (99), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 27/87 (31%), Positives = 47/87 (54%), Gaps = 3/87 (3%)
 Frame = +1

Query: 120 RNVLHRDLKPQNLLINRNGELKLADFGLARAFGIP--VRCYSAEVVTLWYRPPDVLFGAK 177
           R  +HRDL  +N L+  +  +K++DFGLAR+       R    + + + + P + +   K
Sbjct: 1   RGYVHRDLATRNCLVGHDLVVKISDFGLARSVHSVDYYRGSEHDAIPIRWMPLEAILYNK 180

Query: 178 LYSTSIDMWSAGCIFAEL-ANAGRPLF 203
            +ST  D+WS G +  E+ A A +P +
Sbjct: 181 -FSTQSDVWSFGVVLWEIFAFALQPYY 258
>36481
          Length = 806

 Score = 42.7 bits (99), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 34/130 (26%), Positives = 62/130 (47%), Gaps = 7/130 (5%)
 Frame = +2

Query: 11  GEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKHKN------IV 64
           GEGT+G V + K+    + +ALK ++   + +    +A  EI +L++L+ K+       V
Sbjct: 389 GEGTFGKVVQCKDLLKGDDIALKIIK---NVDKYREAAKLEINVLEKLREKDPHAKHMCV 559

Query: 65  RLHDVLHSDKKLTLVFEFCDQDLKKYF-DSCNGDLDPEIVKSFLFQLLKGLGFCHSRNVL 123
           ++ D       + + F      +  +  D+  G    E V+   +QL   + F H   + 
Sbjct: 560 QMLDWFDYHGHVCISFHMLGLSVFDFLKDNSYGAYPIEQVRHISYQLCYAVNFLHENQLT 739

Query: 124 HRDLKPQNLL 133
           H DLKP+N+L
Sbjct: 740 HTDLKPENIL 769
>02638
          Length = 1490

 Score = 42.4 bits (98), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 34/126 (26%), Positives = 57/126 (45%)
 Frame = +1

Query: 164 TLWYRPPDVLFGAKLYSTSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPT 223
           T+ +  P+VL G   Y  + D+WS GC+  E+    RP +  +D+ + L  IF++  +  
Sbjct: 25  TIAFMAPEVLRGES-YGRACDVWSVGCVMIEMCTC-RPPWNSHDISNHLALIFKIASS-- 192

Query: 224 EEQWPAMTKLPDYKPYPMYPATTSLVNVVPKLNATGRDLLQNLLKCNPVQRISAEEALQH 283
                      D  P P         N+ P +    RDL+   L+ +   R SA++ L H
Sbjct: 193 ----------VDPPPIP--------ENMSPPV----RDLMLRCLEQDSDFRPSAKDLLMH 306

Query: 284 PYFSDF 289
           P F+ +
Sbjct: 307 PLFTKY 324
>11404
          Length = 563

 Score = 41.6 bits (96), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 40/141 (28%), Positives = 68/141 (48%), Gaps = 9/141 (6%)
 Frame = +1

Query: 3   KYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKHKN 62
           +YE    IG+G++G V KA +   +E VA+K ++   + +   + A  E+ LL+ +   +
Sbjct: 142 RYEIDSLIGKGSFGQVVKAYDHTDNEQVAIKIIK---NKKPFLNQAQIEVKLLEMMNRHD 312

Query: 63  ------IVRLHDVLHSDKKLTLVFEFCDQDLKKYFDSCN-GDLDPEIVKSFLFQLLKGLG 115
                 IVRL         L LVFE    +L     + N   +   + + F  QL   L 
Sbjct: 313 TDNKYYIVRLKRHFMFRSHLCLVFELLSYNLYDLLRNTNFRGVSLNLTRKFAQQLCTALL 492

Query: 116 FCHS--RNVLHRDLKPQNLLI 134
           F  +   +++H DLKP+N+L+
Sbjct: 493 FLATPEMSIIHCDLKPENILL 555
>05084
          Length = 1324

 Score = 40.8 bits (94), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 29/89 (32%), Positives = 39/89 (43%), Gaps = 2/89 (2%)
 Frame = +2

Query: 203 FPGNDVDDQLKRIFRLLGTPTEEQWPAMTKLPDYKP--YPMYPATTSLVNVVPKLNATGR 260
            PG+   DQL  I ++LGTPT EQ   M   P+Y    +P   A        P+      
Sbjct: 2   LPGDSGVDQLVEIIKVLGTPTREQIREMN--PNYSEFKFPQIKAHPWTKVFRPRTPPEAI 175

Query: 261 DLLQNLLKCNPVQRISAEEALQHPYFSDF 289
            L+  LL+  P  RI   EA  H +F + 
Sbjct: 176 QLVSRLLEYTPSARIQPMEACAHAFFDEL 262
>13840
          Length = 446

 Score = 40.4 bits (93), Expect = 8e-04,   Method: Compositional matrix adjust.
 Identities = 28/128 (21%), Positives = 61/128 (47%), Gaps = 5/128 (3%)
 Frame = -1

Query: 5   EKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKHKNIV 64
           + + +IG G YGTV K +++ T  ++A+KR+R   ++       +    +++      IV
Sbjct: 386 QDMGEIGRGNYGTVNKMRHKITSTVMAVKRIRSTVEEREQKQLLMDLDVVMRSNNCPFIV 207

Query: 65  RLHDVLHSDKKLTLVFEFCDQDLKKYFDSCNGDLDPEIVKSFLFQL----LKGLGFCHSR 120
           + +  L  +    +  E  +  L K++    G++   I ++ L ++    LK L +    
Sbjct: 206 QFYGALFKEGDCWICMELMETSLDKFYKFVYGEMQSSIPENILGKITVATLKALNYLKEE 27

Query: 121 -NVLHRDL 127
             ++HRD+
Sbjct: 26  LRIIHRDV 3
>26009
          Length = 886

 Score = 40.4 bits (93), Expect = 8e-04,   Method: Compositional matrix adjust.
 Identities = 16/32 (50%), Positives = 24/32 (75%)
 Frame = +3

Query: 103 VKSFLFQLLKGLGFCHSRNVLHRDLKPQNLLI 134
            KS + QL+  L F HS+ ++HRD+KP+N+LI
Sbjct: 717 AKSVMKQLVSALDFMHSKQLVHRDIKPENVLI 812

 Score = 29.3 bits (64), Expect = 2.1,   Method: Compositional matrix adjust.
 Identities = 14/32 (43%), Positives = 20/32 (62%)
 Frame = +2

Query: 2   QKYEKLEKIGEGTYGTVFKAKNRETHEIVALK 33
           + Y+  +++G GTYG V  A+ R T   VALK
Sbjct: 416 EHYDVCKELGRGTYGKVVLARCRHTGTQVALK 511
>15549
          Length = 470

 Score = 40.0 bits (92), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 19/54 (35%), Positives = 35/54 (64%)
 Frame = -1

Query: 3   KYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLK 56
           ++E +E++G+G YG VF+AKN+   +  A+KR+ L  D      +A+++ C +K
Sbjct: 215 EFECIEQMGKGGYGIVFRAKNKVDEQEYAVKRIALPSD------AAVKKRCCVK 72
>18481
          Length = 437

 Score = 39.7 bits (91), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 25/78 (32%), Positives = 36/78 (46%), Gaps = 3/78 (3%)
 Frame = -1

Query: 77  TLVFEFCDQDLKKYFDSCNGDLDPEIVKSFLFQLLKGLGFCHSRNVLHRDLKPQNLLINR 136
            LV E     L++ F  C      + +     QLL  L F H +  +HRDLKP N L+  
Sbjct: 269 ALVMELLGPSLEELFVICKRRFTLKTILMVSDQLLSRLEFIHQKCFIHRDLKPDNFLMGL 90

Query: 137 N---GELKLADFGLARAF 151
                 L + DFGL++ +
Sbjct: 89  GRHCHRLYIIDFGLSKRY 36
>21800
          Length = 855

 Score = 38.9 bits (89), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 35/109 (32%), Positives = 55/109 (50%), Gaps = 2/109 (1%)
 Frame = +2

Query: 28  EIVALKRVRLDDDDEGVPSSALREICLLKELKHKNIVRLHDVLHSDKKLTLVFEFCDQDL 87
           EI  LK VR  + DE  P+   + + LL + K   +   H        + +VFE    +L
Sbjct: 443 EIKLLKCVR--NSDETDPARE-KSVQLLDDFKISGVNGTH--------VCMVFEVLGYNL 589

Query: 88  KKYFDSCNGDLDP-EIVKSFLFQLLKGLGFCHSR-NVLHRDLKPQNLLI 134
            K     N    P   VK  + Q+L+GL + H++ N++H D+KP+N+LI
Sbjct: 590 LKLIIRSNYQGIPVHNVKLIIRQVLEGLNYLHAKCNIIHTDIKPENILI 736
>16350
          Length = 1108

 Score = 36.6 bits (83), Expect = 0.011,   Method: Compositional matrix adjust.
 Identities = 27/86 (31%), Positives = 39/86 (45%), Gaps = 5/86 (5%)
 Frame = +2

Query: 140 LKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKLYSTSIDMWSAGCIFAELANAG 199
           +K+AD G A         ++ ++ T  YR  +VL GA  Y T  D+WS  C+  ELA   
Sbjct: 356 VKIADLGNAC---WTYHHFTEDIQTRQYRCLEVLIGAG-YGTPADIWSTACMAFELATGD 523

Query: 200 RPLFPGNDVD-----DQLKRIFRLLG 220
               P +  D     D L  +  L+G
Sbjct: 524 YLFEPHSGEDYSRDEDHLAHVIELVG 601
>31789
          Length = 676

 Score = 36.2 bits (82), Expect = 0.015,   Method: Compositional matrix adjust.
 Identities = 32/111 (28%), Positives = 55/111 (49%), Gaps = 5/111 (4%)
 Frame = +2

Query: 9   KIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKHKNIVRLHD 68
           +IG G++ TV+K  + E    VA   ++    ++        E  +LKEL+H NIVR  D
Sbjct: 341 EIGRGSFKTVYKGLDTELGVAVAWCELQDKKWNKTERQRFKEEAEMLKELQHPNIVRFFD 520

Query: 69  VL----HSDKK-LTLVFEFCDQDLKKYFDSCNGDLDPEIVKSFLFQLLKGL 114
                 H ++K + LV E       K +      ++ +++K++  Q+LKGL
Sbjct: 521 YWEEHNHRNRKVIILVTELMTSGTLKTYLKRFKKINLKVLKNWCRQILKGL 673
>07836
          Length = 1478

 Score = 35.0 bits (79), Expect = 0.035,   Method: Compositional matrix adjust.
 Identities = 13/27 (48%), Positives = 20/27 (74%)
 Frame = -1

Query: 122  VLHRDLKPQNLLINRNGELKLADFGLA 148
            + HRD+K +N+L+ +NG   +AD GLA
Sbjct: 1169 IAHRDIKSKNILVKKNGTCCIADLGLA 1089
>12672
          Length = 773

 Score = 33.9 bits (76), Expect = 0.080,   Method: Compositional matrix adjust.
 Identities = 22/88 (25%), Positives = 40/88 (45%), Gaps = 4/88 (4%)
 Frame = +3

Query: 112 KGLGFCHSRNVLHRDLKPQNLLINRNGELKLADFGLARAF----GIPVRCYSAEVVTLWY 167
            G+ + +    +HRD+K  N+L++     K+ DF    +     G  V+  S  + T  Y
Sbjct: 24  SGIQYLNDNGHVHRDIKTANILLDSEYTAKVGDFATVVSAPSGEGKTVQNASVVIGTAAY 203

Query: 168 RPPDVLFGAKLYSTSIDMWSAGCIFAEL 195
             P+ +      ST +D +S G +  E+
Sbjct: 204 LAPEAIHFD--VSTKLDSYSFGVVLLEV 281
>29360
          Length = 363

 Score = 33.1 bits (74), Expect = 0.12,   Method: Compositional matrix adjust.
 Identities = 32/124 (25%), Positives = 55/124 (44%), Gaps = 9/124 (7%)
 Frame = +3

Query: 20  KAKNRETHEIVALKRVRLDDDDEGVPSSALR---EICLLKELKHK-----NIVRLHDVLH 71
           K   + T EIVA+K ++        PS A +   E+ +L+ L  +     N VR  +   
Sbjct: 6   KCWKKGTSEIVAIKILK------NHPSYARQGQIEVSILQRLSQESADDYNFVRAFECFQ 167

Query: 72  SDKKLTLVFEFCDQDLKKYFDSCNGDLDP-EIVKSFLFQLLKGLGFCHSRNVLHRDLKPQ 130
                 LVFE  +Q+L  +         P + ++    Q+L  L       ++H DLKP+
Sbjct: 168 HKNHTCLVFEMLEQNLYDFLKQNKFQPLPLKYIRPITQQVLTALRKLKQLGLIHADLKPE 347

Query: 131 NLLI 134
           N+++
Sbjct: 348 NIML 359
>13078
          Length = 773

 Score = 33.1 bits (74), Expect = 0.13,   Method: Compositional matrix adjust.
 Identities = 17/43 (39%), Positives = 24/43 (55%)
 Frame = -1

Query: 179 YSTSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGT 221
           +S   D+WS GCI  EL   G  LF  +D  + L  + R+LG+
Sbjct: 746 WSQPCDVWSIGCIMFELYT-GYTLFQTHDNKEHLAMMERILGS 621
>00394
          Length = 548

 Score = 32.0 bits (71), Expect = 0.29,   Method: Compositional matrix adjust.
 Identities = 22/75 (29%), Positives = 38/75 (50%), Gaps = 4/75 (5%)
 Frame = -2

Query: 9   KIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKHKNIVRLHD 68
           +IG G++ TV+K  + E    VA   ++    ++        E  +LKEL+H NIVR  D
Sbjct: 277 EIGRGSFKTVYKGLDTELGVAVAWCELQDKKWNKAERQRFKEEAEMLKELQHPNIVRFFD 98

Query: 69  VL----HSDKKLTLV 79
                 H ++K+ ++
Sbjct: 97  YWEEHNHRNRKVIIL 53
>14104
          Length = 573

 Score = 28.9 bits (63), Expect = 2.6,   Method: Compositional matrix adjust.
 Identities = 13/44 (29%), Positives = 21/44 (47%)
 Frame = +1

Query: 243 PATTSLVNVVPKLNATGRDLLQNLLKCNPVQRISAEEALQHPYF 286
           P      N  P+        +Q+ LK +P +R++  + LQHPY 
Sbjct: 64  PLEEKFSNAAPQ----AMSFMQSCLKMDPAERLTCHQLLQHPYM 183
>33679
          Length = 407

 Score = 28.5 bits (62), Expect = 3.7,   Method: Compositional matrix adjust.
 Identities = 11/21 (52%), Positives = 14/21 (66%)
 Frame = +3

Query: 71 HSDKKLTLVFEFCDQDLKKYF 91
          + DK L  +F +CD DLKK F
Sbjct: 15 YPDKNLPTIFVYCDNDLKKQF 77
>00842
          Length = 1507

 Score = 28.1 bits (61), Expect = 4.0,   Method: Compositional matrix adjust.
 Identities = 11/17 (64%), Positives = 14/17 (82%)
 Frame = -2

Query: 270  NPVQRISAEEALQHPYF 286
            +P QRISA+EAL H +F
Sbjct: 1506 DPSQRISADEALNHDFF 1456
>24983
          Length = 433

 Score = 27.7 bits (60), Expect = 5.3,   Method: Compositional matrix adjust.
 Identities = 14/49 (28%), Positives = 24/49 (48%)
 Frame = -2

Query: 55  LKELKHKNIVRLHDVLHSDKKLTLVFEFCDQDLKKYFDSCNGDLDPEIV 103
           +  L H ++   +  +H D    L +   D  L++YFD   GD+D  +V
Sbjct: 363 VSHLSHTSLAPSNSHIHQDLLGGLPYHTTDHSLREYFDKF-GDIDEAVV 220
>00331
          Length = 1519

 Score = 27.7 bits (60), Expect = 5.9,   Method: Compositional matrix adjust.
 Identities = 13/43 (30%), Positives = 23/43 (53%)
 Frame = +2

Query: 219 LGTPTEEQWPAMTKLPDYKPYPMYPATTSLVNVVPKLNATGRD 261
           +G PT+  W  + +  D++P P++  T   V VV +L   G +
Sbjct: 170 IGQPTKSHWLKIKRRKDFQPLPLWCITEKXV-VVCELQEGGAE 295
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6755262|ref|NP_035359.1| RAB5B, member RAS oncogene
family isoform 2 [Mus musculus]
         (215 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

33374                                                                 234   2e-82
08428                                                                 190   3e-49
01095                                                                 173   4e-44
34468                                                                 126   8e-30
26083                                                                 121   2e-28
17511                                                                 110   4e-25
14456                                                                 110   5e-25
29380                                                                 105   2e-23
07580                                                                  88   3e-22
07465                                                                  99   2e-21
33794                                                                  96   2e-20
05468                                                                  90   6e-19
13750                                                                  89   1e-18
01972                                                                  76   2e-18
14119                                                                  85   3e-17
26536                                                                  84   3e-17
11257                                                                  82   1e-16
32723                                                                  81   3e-16
01398                                                                  81   3e-16
13901                                                                  81   4e-16
33380                                                                  80   5e-16
25618                                                                  78   3e-15
19006                                                                  77   5e-15
30760                                                                  77   7e-15
12339                                                                  75   2e-14
09204                                                                  72   2e-13
35581                                                                  71   3e-13
34359                                                                  71   3e-13
13745                                                                  71   4e-13
00858                                                                  64   3e-11
27191                                                                  59   4e-11
11728                                                                  63   1e-10
34597                                                                  55   2e-08
14775                                                                  55   3e-08
19656                                                                  53   8e-08
31291                                                                  47   5e-06
00552                                                                  47   6e-06
08153                                                                  45   2e-05
10862                                                                  41   3e-04
09827                                                                  40   5e-04
18509                                                                  37   0.007
10708                                                                  36   0.012
06994                                                                  34   0.044
33605                                                                  33   0.068
34156                                                                  30   1.1  
19310                                                                  27   1.5  
30516                                                                  28   2.3  
25991                                                                  28   3.0  
25795                                                                  27   6.7  
>33374
          Length = 489

 Score =  234 bits (598), Expect(2) = 2e-82,   Method: Compositional matrix adjust.
 Identities = 109/119 (91%), Positives = 117/119 (98%)
 Frame = +1

Query: 55  AAFLTQSVCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNQETFARAKTW 114
           + FLTQ+VCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNQ+TF RAKTW
Sbjct: 133 SCFLTQTVCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNQDTFGRAKTW 312

Query: 115 VKELQRQASPSIVIALAGNKADLANKRMVEYEEAQAYADDNSLLFMETSAKTAMNVNDL 173
           VKELQRQASP+IVIALAGNKADLANKRMVE+EEAQAYA++NSLLFMETSAKTAMNVND+
Sbjct: 313 VKELQRQASPNIVIALAGNKADLANKRMVEFEEAQAYAEENSLLFMETSAKTAMNVNDI 489

 Score = 88.2 bits (217), Expect(2) = 2e-82,   Method: Compositional matrix adjust.
 Identities = 44/48 (91%), Positives = 44/48 (91%)
 Frame = +2

Query: 10 NGQPQASKICQFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAF 57
          NG  Q  KICQFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAF
Sbjct: 2  NGATQG-KICQFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAF 142
>08428
          Length = 1109

 Score =  190 bits (483), Expect = 3e-49,   Method: Compositional matrix adjust.
 Identities = 89/178 (50%), Positives = 126/178 (70%)
 Frame = -3

Query: 8    RPNGQPQASKICQFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQSVCLDDT 67
            R  G+    ++   K+ LLG+S VGKSS+VLRFV G +   QESTIGA+F+++S+ +D  
Sbjct: 1107 RGEGELMRMQMRDVKVCLLGDSGVGKSSIVLRFVTGSYRPSQESTIGASFMSKSLVVDGA 928

Query: 68   TVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNQETFARAKTWVKELQRQASPSIV 127
              +F+IWDTAGQE++ +LAPMYYRGA AA++VYD+T   TF   K+W++EL+    P+IV
Sbjct: 927  GYRFQIWDTAGQEKFRALAPMYYRGAAAAVIVYDVTRPRTFKSVKSWIQELRSFGPPNIV 748

Query: 128  IALAGNKADLANKRMVEYEEAQAYADDNSLLFMETSAKTAMNVNDLFLAIAKKLPKSE 185
            +A+AGNK DL   R V  ++AQ YA   S +F ETSA TA+NV ++F  +A++LP  E
Sbjct: 747  LAIAGNKCDLEELREVVEKDAQEYASSISAIFGETSAMTAVNVEEMFTELARQLPPEE 574
>01095
          Length = 1745

 Score =  173 bits (439), Expect = 4e-44,   Method: Compositional matrix adjust.
 Identities = 86/105 (81%), Positives = 96/105 (91%)
 Frame = -1

Query: 98   VVYDITNQETFARAKTWVKELQRQASPSIVIALAGNKADLANKRMVEYEEAQAYADDNSL 157
            VVYDITNQ+TF RAKTWVKELQRQASP+IVIALAGNKADLANKRMVE+EEAQAYA++NSL
Sbjct: 1745 VVYDITNQDTFGRAKTWVKELQRQASPNIVIALAGNKADLANKRMVEFEEAQAYAEENSL 1566

Query: 158  LFMETSAKTAMNVNDLFLAIAKKLPKSEPQNLGGAAGRSRGVDLH 202
            LFMETSAKTAMNVND+FLAIAKKLPK+E    GG+  R +GV L+
Sbjct: 1565 LFMETSAKTAMNVNDIFLAIAKKLPKNEGG--GGSQPRQQGVRLN 1437
>34468
          Length = 1502

 Score =  126 bits (316), Expect = 8e-30,   Method: Compositional matrix adjust.
 Identities = 65/171 (38%), Positives = 100/171 (58%), Gaps = 5/171 (2%)
 Frame = +1

Query: 21  FKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQSVCLDDTTVKFEIWDTAGQE 80
           FK++++G+S VGK+ L  RF  G+F +  E+TIG  F  +S+ +D   +K ++WDTAGQE
Sbjct: 496 FKIIVIGDSNVGKTCLTYRFCLGKFPDKTEATIGVDFREKSIQVDSEHLKLQLWDTAGQE 675

Query: 81  RYH-SLAPMYYRGAQAAIVVYDITNQETFARAKTWVKELQRQ-ASPSIVIALAGNKADLA 138
           R+  S+   YYR   A + VYD+T   +F     W++E  R   +  I   L GNK D+ 
Sbjct: 676 RFRKSMVQHYYRNVHAVVFVYDMTKMSSFENMPAWIEECDRHNLTKYIPRILVGNKCDVV 855

Query: 139 NKRMVEYEEAQAYADDNSLLFMETSAK---TAMNVNDLFLAIAKKLPKSEP 186
            +  V    AQ +AD +++   ETSAK    A +V+ +F+ +A KL  S+P
Sbjct: 856 ERIAVNTNLAQKFADAHNMPLFETSAKDDEKANHVDAIFMTVAHKLKXSKP 1008
>26083
          Length = 432

 Score =  121 bits (304), Expect = 2e-28,   Method: Compositional matrix adjust.
 Identities = 51/115 (44%), Positives = 79/115 (68%)
 Frame = +1

Query: 20  QFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQSVCLDDTTVKFEIWDTAGQ 79
           +FKLV LGE +VGK+SL+ RF+   F    ++TIG  FL++++ L+D T++ ++WDTAGQ
Sbjct: 76  KFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTIRLQLWDTAGQ 255

Query: 80  ERYHSLAPMYYRGAQAAIVVYDITNQETFARAKTWVKELQRQASPSIVIALAGNK 134
           ER+ SL P Y R +  A+VVYDITN  +F +   W+ +++ +    ++I L GNK
Sbjct: 256 ERFRSLIPSYIRDSSVAVVVYDITNANSFHQTSKWIDDVRTERGSDVIIMLVGNK 420
>17511
          Length = 483

 Score =  110 bits (275), Expect = 4e-25,   Method: Compositional matrix adjust.
 Identities = 53/120 (44%), Positives = 76/120 (63%), Gaps = 4/120 (3%)
 Frame = -3

Query: 22  KLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQSVCLDDTTVKFEIWDTAGQER 81
           K+++LG+S VGK+SL+ ++V  +F    ++TIGA FLT+ V +DD  V  +IWDTAGQER
Sbjct: 361 KVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQIWDTAGQER 182

Query: 82  YHSLAPMYYRGAQAAIVVYDITNQETFARAKTWVKELQRQASP----SIVIALAGNKADL 137
           + SL   +YRGA   ++V+D+T   TF    +W  E   QASP    +    + GNK DL
Sbjct: 181 FQSLGVAFYRGADCCVLVFDVTMPNTFRSLDSWRDEFLIQASPRDPENFPFVVIGNKIDL 2
>14456
          Length = 1867

 Score =  110 bits (275), Expect = 5e-25,   Method: Compositional matrix adjust.
 Identities = 65/167 (38%), Positives = 90/167 (53%), Gaps = 5/167 (2%)
 Frame = -1

Query: 26   LGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQSVCLDDTTVKFEIWDTAGQERYHSL 85
            L +  VGKSSL+ RFV  +F      TIG  FL + V +DD T   +IWDTAGQER+ SL
Sbjct: 1123 LKQGGVGKSSLMNRFVSNKFDAQSFHTIGVEFLNKDVVVDDETYTMQIWDTAGQERFKSL 944

Query: 86   APMYYRGAQAAIVVYDITNQETFARAKTWVKEL----QRQASPSIVIALAGNKADLANKR 141
               +YRGA   ++ + + + ++F     W KE       Q   +    + GNK D+   R
Sbjct: 943  RTPFYRGADCCLLTFSVDSMQSFRNLSMWRKEFLYYADIQDGVTFPFVVLGNKIDVEG-R 767

Query: 142  MVEYEEAQAYADDNS-LLFMETSAKTAMNVNDLFLAIAKKLPKSEPQ 187
             V  EEA+++   NS   + ETSAK A NV   FLA  ++L + E Q
Sbjct: 766  QVTNEEARSWCTANSNAPYFETSAKDATNVEKAFLAAVQRLREVEDQ 626
>29380
          Length = 853

 Score =  105 bits (261), Expect = 2e-23,   Method: Compositional matrix adjust.
 Identities = 54/111 (48%), Positives = 77/111 (69%), Gaps = 1/111 (0%)
 Frame = -2

Query: 93  AQAAIVVYDITNQETFARAKTWVKELQRQASPSIVIALAGNKADLANK-RMVEYEEAQAY 151
           A AAI+VYD+   +TF+RA  WVKEL++Q + S++I LAGNK DLA + R V +E+AQ++
Sbjct: 852 ASAAIIVYDVNIADTFSRALAWVKELRQQNTESVLIILAGNKVDLATQHRAVSFEDAQSF 673

Query: 152 ADDNSLLFMETSAKTAMNVNDLFLAIAKKLPKSEPQNLGGAAGRSRGVDLH 202
           A +N LLF E SAKT M VN++F+ +A +L + E         R+RGV L+
Sbjct: 672 ARENGLLFAEVSAKTGMAVNEIFMTLANQLIQQEID-----GSRNRGVTLN 535
>07580
          Length = 921

 Score = 87.8 bits (216), Expect(2) = 3e-22,   Method: Compositional matrix adjust.
 Identities = 49/152 (32%), Positives = 84/152 (55%), Gaps = 1/152 (0%)
 Frame = +3

Query: 40  FVKGQFHEYQESTIGAAFLTQSVCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVV 99
             KG F E  + TI  ++  Q V +D      EI DTAG E++ ++  +Y +  Q  ++ 
Sbjct: 120 LCKGIFVEKYDPTIEDSYRKQ-VEVDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFLLA 296

Query: 100 YDITNQETFARAKTWVKELQR-QASPSIVIALAGNKADLANKRMVEYEEAQAYADDNSLL 158
           Y IT Q TF   +   +++ R + +  + + L GNK DL ++R+V  ++ Q  A   S  
Sbjct: 297 YSITAQSTFNDLQELREQILRVKDTDDVPMLLVGNKCDLEDERVVGKDQGQGLARSFSCA 476

Query: 159 FMETSAKTAMNVNDLFLAIAKKLPKSEPQNLG 190
           F+ETSAK  +NVN++F+ + +++ K  P+  G
Sbjct: 477 FLETSAKARINVNEIFMDLVRQINKKSPEQSG 572

 Score = 33.9 bits (76), Expect(2) = 3e-22,   Method: Compositional matrix adjust.
 Identities = 14/26 (53%), Positives = 21/26 (80%)
 Frame = +2

Query: 20 QFKLVLLGESAVGKSSLVLRFVKGQF 45
          ++KLV+LG   VGKS+L ++FV+G F
Sbjct: 59 EYKLVVLGSGGVGKSALTVQFVQGDF 136
>07465
          Length = 1103

 Score = 98.6 bits (244), Expect = 2e-21,   Method: Compositional matrix adjust.
 Identities = 50/147 (34%), Positives = 85/147 (57%)
 Frame = +3

Query: 34  SSLVLRFVKGQFHEYQESTIGAAFLTQSVCLDDTTVKFEIWDTAGQERYHSLAPMYYRGA 93
           SS++ R+ KG F +  + TIG  FL + + +    V+  +WDTAGQE + ++   YYRGA
Sbjct: 240 SSMIQRYCKGIFTKDYKKTIGVDFLERQIEVGGEDVRLMLWDTAGQEEFDAITKAYYRGA 419

Query: 94  QAAIVVYDITNQETFARAKTWVKELQRQASPSIVIALAGNKADLANKRMVEYEEAQAYAD 153
           QA ++ +   ++++F   +TW ++++ +    I + +  NK DL +  +V  EEA+  A 
Sbjct: 420 QACVLAFSTVDRDSFEALETWKRKVEDEVG-EIGMVIVQNKIDLIDDAVVRPEEAENLAK 596

Query: 154 DNSLLFMETSAKTAMNVNDLFLAIAKK 180
              L F  TS K  MNV+++F  +A K
Sbjct: 597 KLRLRFYRTSVKENMNVDEVFRYLADK 677
>33794
          Length = 779

 Score = 95.5 bits (236), Expect = 2e-20,   Method: Compositional matrix adjust.
 Identities = 48/125 (38%), Positives = 73/125 (58%)
 Frame = -1

Query: 55  AAFLTQSVCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNQETFARAKTW 114
            A+ T ++ L+   VK +IWDT+GQ R+ ++   Y RGAQ  I+VYDITN+ +F     W
Sbjct: 692 VAYKTTTILLEGKRVKLQIWDTSGQGRFCTIIRSYSRGAQGIILVYDITNKWSFDGIDRW 513

Query: 115 VKELQRQASPSIVIALAGNKADLANKRMVEYEEAQAYADDNSLLFMETSAKTAMNVNDLF 174
           +KE++  A P I   L GN+  LA KR V  ++A+ YA  N++   E S     N+ + F
Sbjct: 512 LKEVEEHA-PGIPKVLVGNRLHLAYKRQVAAKQAETYASRNNMSCFEISPLCDFNIRESF 336

Query: 175 LAIAK 179
             +A+
Sbjct: 335 CELAR 321
>05468
          Length = 1558

 Score = 90.1 bits (222), Expect = 6e-19,   Method: Compositional matrix adjust.
 Identities = 56/180 (31%), Positives = 97/180 (53%), Gaps = 10/180 (5%)
 Frame = -3

Query: 21   FKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQSVCLD-DTTVKFEIWDTAGQ 79
            +K++++GE   GK+S++ R+V   F ++  +TIG  F  + +  D DT ++ ++WD AGQ
Sbjct: 1538 YKILVIGELGTGKTSIIKRYVHQFFSQHYRATIGVDFALKVLNWDADTLIRLQLWDIAGQ 1359

Query: 80   ERYHSLAPMYYRGAQAAIVVYDITNQETFARAKTWVKELQRQ-----ASPSIVIALAGNK 134
            ER+ ++  +YY+ A  A VV+D+T   TF     W  +L  +      SP   + LA NK
Sbjct: 1358 ERFGNMTRVYYKEAVGAFVVFDVTRASTFDAVTKWKNDLDSKVQLADGSPVPCVLLA-NK 1182

Query: 135  ADLANKRMV-EYEEAQAYADDNSLL-FMETSAKTAMNVNDL--FLAIAKKLPKSEPQNLG 190
             D A + +V    +   +  +   + + ETSAK  +N+++   FL + + L K     LG
Sbjct: 1181 CDQAKEGLVNNTSQMDEFCSEKGFIGWYETSAKENINIDEAARFL-VTRILEKDRAMQLG 1005
>13750
          Length = 503

 Score = 89.4 bits (220), Expect = 1e-18,   Method: Compositional matrix adjust.
 Identities = 55/159 (34%), Positives = 80/159 (50%), Gaps = 8/159 (5%)
 Frame = -2

Query: 33  KSSLVLRFVKGQFHEYQESTIGAAFLTQSVC-------LDDTTVKFEIWDTAGQERYHSL 85
           K+ L+ R+ KG F +    TI        +C        D   V++ +WDT G E Y SL
Sbjct: 502 KTCLLRRYQKGFFMDRTMPTIAV------LCSEFNESRTDPLNVRYTLWDTGGAETYRSL 341

Query: 86  APMYYRGAQAAIVVYDITNQETFARAKT-WVKELQRQASPSIVIALAGNKADLANKRMVE 144
              ++RGAQ A++VYD+T + +F  A T W K L +   P   +   G+K DL   R++ 
Sbjct: 340 WVSHFRGAQVALLVYDVTCEWSFLTATTVWRKALMKNI-PEAQVIFVGSKTDLEENRVIS 164

Query: 145 YEEAQAYADDNSLLFMETSAKTAMNVNDLFLAIAKKLPK 183
            E  QA+A      F ETS+ T  NV+ +F  IA  L +
Sbjct: 163 TERGQAFATQCGYTFFETSSVTGKNVDAVFWEIAFILAR 47
>01972
          Length = 2359

 Score = 75.9 bits (185), Expect(2) = 2e-18,   Method: Compositional matrix adjust.
 Identities = 38/113 (33%), Positives = 66/113 (58%)
 Frame = +3

Query: 69  VKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNQETFARAKTWVKELQRQASPSIVI 128
           +KF +WDTAGQE++  L   YY   Q A++++D+T++ T+     W ++L R    +I I
Sbjct: 447 LKFNVWDTAGQEKFGGLRDGYYIQGQCAVIMFDVTSRVTYKNVPNWHRDLVRVCE-NIPI 623

Query: 129 ALAGNKADLANKRMVEYEEAQAYADDNSLLFMETSAKTAMNVNDLFLAIAKKL 181
            L GNK D+ ++++    +A  +    +L + + SAK+  N    FL +A+KL
Sbjct: 624 VLCGNKVDIKDRKV--KAKAIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKL 776

 Score = 33.5 bits (75), Expect(2) = 2e-18,   Method: Compositional matrix adjust.
 Identities = 14/27 (51%), Positives = 20/27 (74%)
 Frame = +1

Query: 21  FKLVLLGESAVGKSSLVLRFVKGQFHE 47
           FKLVL+G+  VGK++ V R V G+F +
Sbjct: 304 FKLVLVGDGGVGKTTFVKRHVTGEFEK 384
>14119
          Length = 602

 Score = 84.7 bits (208), Expect = 3e-17,   Method: Compositional matrix adjust.
 Identities = 42/85 (49%), Positives = 61/85 (71%), Gaps = 1/85 (1%)
 Frame = +1

Query: 107 TFARAKTWVKELQRQASPSIVIALAGNKADLANK-RMVEYEEAQAYADDNSLLFMETSAK 165
           TF RA  WVKEL++Q + S++I LAGNKADLA++ R V  ++A+ +A+DN L+F E SAK
Sbjct: 1   TFNRALAWVKELRQQNAGSVLIVLAGNKADLASEHRAVSADDARTFAEDNGLIFAEVSAK 180

Query: 166 TAMNVNDLFLAIAKKLPKSEPQNLG 190
           T M V+++F+ IA KL +   +  G
Sbjct: 181 TGMAVSEVFMTIAHKLVRRAEEGGG 255
>26536
          Length = 829

 Score = 84.3 bits (207), Expect = 3e-17,   Method: Compositional matrix adjust.
 Identities = 51/136 (37%), Positives = 71/136 (52%), Gaps = 1/136 (0%)
 Frame = +2

Query: 50  ESTIGAAFLTQSVCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNQETFA 109
           E TI    LT    + +  V +   DTAGQE Y S+   Y R     IVVY +T+  +F 
Sbjct: 71  ERTIMLLSLTTMKMMMERRVSWTFLDTAGQEEYSSMREHYTRSGDGFIVVYSVTDVTSFQ 250

Query: 110 RAKTWVKELQR-QASPSIVIALAGNKADLANKRMVEYEEAQAYADDNSLLFMETSAKTAM 168
            A+   + L R Q   SI   L GNK DL + R V  EE +  AD   +L+ ETSAKT  
Sbjct: 251 EAEAVFRWLTRFQDETSIHAVLCGNKTDLTSDRKVTPEEGRKMADRLGMLYFETSAKTGD 430

Query: 169 NVNDLFLAIAKKLPKS 184
           NV+ ++  + + +P+S
Sbjct: 431 NVSQVYHGLLRSIPRS 478

 Score = 35.8 bits (81), Expect = 0.013,   Method: Compositional matrix adjust.
 Identities = 15/37 (40%), Positives = 24/37 (64%)
 Frame = +2

Query: 21  FKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAF 57
           +K+V+LG   VGKSSL +RF +  F +  + TI  ++
Sbjct: 488 YKIVMLGSGGVGKSSLTIRFTQDTFLDVYDPTIEDSY 598
>11257
          Length = 1102

 Score = 82.4 bits (202), Expect = 1e-16,   Method: Compositional matrix adjust.
 Identities = 50/147 (34%), Positives = 77/147 (52%), Gaps = 5/147 (3%)
 Frame = -2

Query: 60   QSVCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNQETFARAKTWVKELQ 119
            + V +D  T   +IWDTAGQERY SL   +YRG    ++ + + N ++      W  E  
Sbjct: 1053 KDVVVDGETFTMQIWDTAGQERYKSLRTPFYRGTDCCLLTFSVDNLKSLQSLSDWYDEFV 874

Query: 120  R----QASPSIVIALAGNKADLANKRMVEYEEAQAYADDN-SLLFMETSAKTAMNVNDLF 174
                 Q S S    + GNKAD+  +R V  E+A  +   + +L + ETSAK ++NV   F
Sbjct: 873  NYADIQDSASFPFVIIGNKADI-EEREVSSEDAYNWCRTHGNLPYFETSAKDSLNVQQAF 697

Query: 175  LAIAKKLPKSEPQNLGGAAGRSRGVDL 201
            LA+ ++L + + Q +     R+  VDL
Sbjct: 696  LAVVRRLREMDEQ-MDERPTRTDTVDL 619
>32723
          Length = 384

 Score = 81.3 bits (199), Expect = 3e-16,   Method: Compositional matrix adjust.
 Identities = 42/115 (36%), Positives = 63/115 (54%)
 Frame = +2

Query: 79  QERYHSLAPMYYRGAQAAIVVYDITNQETFARAKTWVKELQRQASPSIVIALAGNKADLA 138
           QER+ S+   YYR A A I+VYD+ +Q+++     W+ E++  A   ++  L GNK D  
Sbjct: 2   QERFRSITQSYYRSANALILVYDVCSQQSYESLPQWIHEIELYAGTKVLAFLVGNKIDQT 181

Query: 139 NKRMVEYEEAQAYADDNSLLFMETSAKTAMNVNDLFLAIAKKLPKSEPQNLGGAA 193
           +KR +     + +A+   + F+ETSAK A NV  LF  IA +L       LG  A
Sbjct: 182 DKREIPTHIGKEFAERYEMRFLETSAKEADNVEKLFSTIAYQLTAQAQGTLGAEA 346
>01398
          Length = 1421

 Score = 81.3 bits (199), Expect = 3e-16,   Method: Compositional matrix adjust.
 Identities = 41/102 (40%), Positives = 58/102 (56%), Gaps = 1/102 (0%)
 Frame = -2

Query: 79   QERYHSLAPMYYRGAQAAIVVYDITNQETFARAKTWVKELQRQASPSIVIALA-GNKADL 137
            QER+ S+   YYR +   I+VYDIT + TF   K W +E +    P   I L  G+K+D 
Sbjct: 1420 QERFRSITRSYYRNSVGVIIVYDITKRSTFENLKQWYEEARNHIEPHKAIFLVLGHKSDR 1241

Query: 138  ANKRMVEYEEAQAYADDNSLLFMETSAKTAMNVNDLFLAIAK 179
             + R V   E + +A+ + L F ETSAK+  N+ D+F  IAK
Sbjct: 1240 EDARQVTAREGRRFAEMHGLKFFETSAKSGHNIEDVFAQIAK 1115
>13901
          Length = 962

 Score = 80.9 bits (198), Expect = 4e-16,   Method: Compositional matrix adjust.
 Identities = 36/95 (37%), Positives = 58/95 (61%), Gaps = 1/95 (1%)
 Frame = -3

Query: 21  FKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQSVCLDD-TTVKFEIWDTAGQ 79
           FK++++G+  VGK+S V R+V   F    + TIG  F  + +   D   +K ++WD AGQ
Sbjct: 285 FKVIIIGDPTVGKTSFVQRYVNDSFRRDYKMTIGVDFALKVIRWSDKCNIKLQLWDIAGQ 106

Query: 80  ERYHSLAPMYYRGAQAAIVVYDITNQETFARAKTW 114
           ER+ S+  +YY+ A A IV++D+T + T+  A  W
Sbjct: 105 ERFTSMTRVYYKDAHACIVMFDLTQKNTYQNAIRW 1
>33380
          Length = 282

 Score = 80.5 bits (197), Expect = 5e-16,   Method: Compositional matrix adjust.
 Identities = 33/77 (42%), Positives = 51/77 (66%)
 Frame = +3

Query: 66  DTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNQETFARAKTWVKELQRQASPS 125
           D  VK +IWDTAGQERY ++   YYRGA   I++YD+TN+E+F   + W  +++  +  +
Sbjct: 51  DKRVKLQIWDTAGQERYRTITTAYYRGAMGFILMYDVTNEESFNAVQDWCTQIKTYSWDN 230

Query: 126 IVIALAGNKADLANKRM 142
             + L GNK DL ++R+
Sbjct: 231 AQVVLVGNKCDLEDERV 281
>25618
          Length = 475

 Score = 77.8 bits (190), Expect = 3e-15,   Method: Compositional matrix adjust.
 Identities = 39/83 (46%), Positives = 58/83 (69%), Gaps = 1/83 (1%)
 Frame = +3

Query: 116 KELQRQASPSIVIALAGNKADLANK-RMVEYEEAQAYADDNSLLFMETSAKTAMNVNDLF 174
           KEL++Q + S++I LAGNKADLA++ R V  ++A+ +A+DN L+F E SAKT M V+++F
Sbjct: 48  KELRQQNAGSVLIVLAGNKADLASEHRAVSADDARTFAEDNGLIFAEVSAKTGMAVSEVF 227

Query: 175 LAIAKKLPKSEPQNLGGAAGRSR 197
           + IA KL +   +  G   GR R
Sbjct: 228 MTIAHKLVRRAEEGQGSXQGRER 296
>19006
          Length = 568

 Score = 77.0 bits (188), Expect = 5e-15,   Method: Compositional matrix adjust.
 Identities = 40/119 (33%), Positives = 64/119 (53%), Gaps = 1/119 (0%)
 Frame = -2

Query: 22  KLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQSVCLDDTTVKFEIWDTAGQER 81
           KLV++G+ A GK+ L++ F K QF E    T+   ++   + +D   V+  +WDTAGQE 
Sbjct: 432 KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVA-DIEVDSKQVELALWDTAGQED 256

Query: 82  YHSLAPMYYRGAQAAIVVYDITNQETFAR-AKTWVKELQRQASPSIVIALAGNKADLAN 139
           Y  L P+ Y      ++ + I + ++     + W  E+ R   P++ I L GNK DL N
Sbjct: 255 YDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEV-RHFCPNVPIILVGNKKDLRN 82
>30760
          Length = 596

 Score = 76.6 bits (187), Expect = 7e-15,   Method: Compositional matrix adjust.
 Identities = 50/168 (29%), Positives = 83/168 (49%), Gaps = 6/168 (3%)
 Frame = -1

Query: 22  KLVLLGESAVGKSSL--VLRFVKGQFHEYQESTIGAAFLTQSVCLDDT--TVKFEIWDTA 77
           K ++ G+S VGKSS+  V       F +    T G   L + V + D+   V+  ++D+A
Sbjct: 524 KCIVTGDSGVGKSSICQVFHSDSAHFPKNYSMTTGVEVLVKLVNIPDSRDQVELYLFDSA 345

Query: 78  GQERYHSLAPMYYRGAQAAIVVYDITNQETFARAKTWVKELQRQASPSIVI--ALAGNKA 135
           G+E +      ++      +VVYD+T++ +F+    W++ + R A P+ VI   L  NK 
Sbjct: 344 GKEIFSENVTKFWDQPSVVMVVYDVTDETSFSGCVRWLERV-RAAKPNTVIPGVLVANKT 168

Query: 136 DLANKRMVEYEEAQAYADDNSLLFMETSAKTAMNVNDLFLAIAKKLPK 183
           DL  +R V  +E +  A  + L + E SAK   N +  F  +A    K
Sbjct: 167 DLDERRRVSRKEGKDLAQSHGLEYFECSAKEMQNTDTPFFCLAHAFHK 24
>12339
          Length = 578

 Score = 74.7 bits (182), Expect = 2e-14,   Method: Compositional matrix adjust.
 Identities = 42/106 (39%), Positives = 57/106 (53%), Gaps = 5/106 (4%)
 Frame = -2

Query: 79  QERYHSLAPMYYRGAQAAIVVYDITNQETFARAKTWVKELQRQASP----SIVIALAGNK 134
           QER+ SL   +YRGA   I+VYD+T  +TF    +W +E   QASP         + GNK
Sbjct: 577 QERFQSLGVAFYRGADCCILVYDVTEXKTFDSLDSWQREFLNQASPRDPEHFPFVVIGNK 398

Query: 135 ADLANKRMVEYEEAQAYAD-DNSLLFMETSAKTAMNVNDLFLAIAK 179
            DL N R+V  +  Q +      + + ETSAK A+NV   F  +AK
Sbjct: 397 IDLDN-RVVTAKRGQGWCSTKGGIPYFETSAKEAINVEQAFQTVAK 263
>09204
          Length = 1051

 Score = 72.0 bits (175), Expect = 2e-13,   Method: Compositional matrix adjust.
 Identities = 40/107 (37%), Positives = 61/107 (57%), Gaps = 4/107 (3%)
 Frame = -3

Query: 81   RYHSLAPMYYRGAQAAIVVYDITNQETFARAKTWVKELQRQASPSIVIALAGNKADLAN- 139
            RY +++ +YYRGA+AAI+ +D+T++ +F R + W+ EL RQ      + + G K DL + 
Sbjct: 1049 RYEAMSRIYYRGAKAAILCFDLTDKSSFDRIRFWIGEL-RQHEEECKLYICGTKFDLVHD 873

Query: 140  ---KRMVEYEEAQAYADDNSLLFMETSAKTAMNVNDLFLAIAKKLPK 183
               +R V    A+A ADD      ETS+ T  N+  LF  IA+   K
Sbjct: 872  DPERRAVPRSVAKALADDCMAEIYETSSMTGDNIEKLFTKIAEDYMK 732
>35581
          Length = 364

 Score = 71.2 bits (173), Expect = 3e-13,   Method: Compositional matrix adjust.
 Identities = 36/93 (38%), Positives = 53/93 (56%), Gaps = 1/93 (1%)
 Frame = +2

Query: 10  NGQPQASKICQFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQSVCLDDTTV 69
           NG    +    FK VLLG++ VGK+ L+ R    +F +   +++  A L  +V L    +
Sbjct: 14  NGIRTGNDTLYFKCVLLGDAGVGKTCLLNRLATDKFLDSPLTSLTTASLLTTVTLTSGVM 193

Query: 70  -KFEIWDTAGQERYHSLAPMYYRGAQAAIVVYD 101
              ++WDTAGQERY SL   YYR  +A ++VYD
Sbjct: 194 ASVDLWDTAGQERYRSLTSSYYRDTKAVLIVYD 292
>34359
          Length = 1042

 Score = 71.2 bits (173), Expect = 3e-13,   Method: Compositional matrix adjust.
 Identities = 39/123 (31%), Positives = 66/123 (53%)
 Frame = +3

Query: 20  QFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQSVCLDDTTVKFEIWDTAGQ 79
            FKLVL+G      +++V R V G   +Y  +T+G              ++F +WDTAGQ
Sbjct: 51  NFKLVLVGGRWEWANNIVKRHVTGS*KKY-VATLGVEVHPLQFNTSRGLLRFNVWDTAGQ 227

Query: 80  ERYHSLAPMYYRGAQAAIVVYDITNQETFARAKTWVKELQRQASPSIVIALAGNKADLAN 139
           E++  L   YY     AI+++D+T++ T+     W ++L R    +I I L GNK D+ +
Sbjct: 228 EKFGGLRDGYYIQGTCAIIMFDVTSRVTYKNVPNWHRDLVRVCE-NIPIVLCGNKVDIKD 404

Query: 140 KRM 142
           +++
Sbjct: 405 RKV 413
>13745
          Length = 1045

 Score = 70.9 bits (172), Expect = 4e-13,   Method: Compositional matrix adjust.
 Identities = 39/105 (37%), Positives = 53/105 (50%), Gaps = 4/105 (3%)
 Frame = +2

Query: 79  QERYHSLAPMYYRGAQAAIVVYDITNQETFARAKTWVKELQRQASP----SIVIALAGNK 134
           QER+ SL   +YRGA   ++VYD+T   +F    +W  E   QASP         + GNK
Sbjct: 2   QERFQSLGVAFYRGADCCVLVYDVTAPNSFKNLDSWRDEFLIQASPRDPEHFPFVVLGNK 181

Query: 135 ADLANKRMVEYEEAQAYADDNSLLFMETSAKTAMNVNDLFLAIAK 179
            DL N+++      Q     N + + ETSAK  +NV   F  IAK
Sbjct: 182 VDLDNRQVSTRRAQQWCQSKNDIPYYETSAKEGINVEMAFQTIAK 316
>00858
          Length = 1658

 Score = 64.3 bits (155), Expect = 3e-11,   Method: Compositional matrix adjust.
 Identities = 47/168 (27%), Positives = 90/168 (53%), Gaps = 1/168 (0%)
 Frame = -2

Query: 15   ASKICQFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQSVCLDDTTVKFEIW 74
             +++ ++KLV++G   VGKS+L ++  +  F E  + T   +   Q V +D  T   +I 
Sbjct: 1606 TTQMTEYKLVVVGAGGVGKSALTIQLXQNHFVEEYDPTXEDSXRKQ-VVIDGETCLLDIL 1430

Query: 75   DTAGQERYHSLAPMYYRGAQAAIVVYDITNQETFARAKTWVKELQR-QASPSIVIALAGN 133
            DTAGQE   ++     R  +  + V+ + N ++F     + ++++R + +  + + L GN
Sbjct: 1429 DTAGQEEXSAMRDQCMRTGEGFLCVFAVXNLKSFEDINQYREQIKRVKDADEVPMVLVGN 1250

Query: 134  KADLANKRMVEYEEAQAYADDNSLLFMETSAKTAMNVNDLFLAIAKKL 181
            K DL   R VE  + +  A+   + ++ETSAKT   V+D F  + +++
Sbjct: 1249 KVDLP-IRNVEQRQGKHMAELYHIPYVETSAKTRQGVDDAFYTLVREI 1109
>27191
          Length = 443

 Score = 58.9 bits (141), Expect(2) = 4e-11,   Method: Compositional matrix adjust.
 Identities = 24/103 (23%), Positives = 55/103 (53%)
 Frame = +1

Query: 33  KSSLVLRFVKGQFHEYQESTIGAAFLTQSVCLDDTTVKFEIWDTAGQERYHSLAPMYYRG 92
           K+ L+  F + +F++  + T+G  +  +   ++   ++  +WD +G   Y  +    Y G
Sbjct: 1   KTCLIKHFCESKFNQGYQPTVGVDYGFKIQTVNGVDMRVHMWDLSGSNEYLDVRNELYTG 180

Query: 93  AQAAIVVYDITNQETFARAKTWVKELQRQASPSIVIALAGNKA 135
           + A  +V+D++N  +F    +W++E+ R A+ S +  + GN+ 
Sbjct: 181 SDAIFIVFDVSNTPSFEALDSWLREINRFATGSPLNVIVGNRV 309

 Score = 25.0 bits (53), Expect(2) = 4e-11,   Method: Compositional matrix adjust.
 Identities = 11/23 (47%), Positives = 14/23 (60%)
 Frame = +2

Query: 152 ADDNSLLFMETSAKTAMNVNDLF 174
           A  N  L+ ETSA T   V+D+F
Sbjct: 356 ALHNKCLYYETSAATGEGVDDMF 424
>11728
          Length = 635

 Score = 62.8 bits (151), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 36/126 (28%), Positives = 61/126 (48%), Gaps = 2/126 (1%)
 Frame = -1

Query: 21  FKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQSVCLDDTTVKFEIWDTAGQE 80
            K V++G+ AVGK+ L++ +    F      T+   + + +V +D   +   +WDTAGQE
Sbjct: 488 IKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNY-SANVMVDSKPINLGLWDTAGQE 312

Query: 81  RYHSLAPMYYRGAQAAIVVYDITNQETFARAKT-WVKELQRQASPSIVIALAGNKADL-A 138
            Y  L P+ Y      ++ + + +  +F   K  W  E+     P+  I L G K DL  
Sbjct: 311 DYDRLRPLSYPQTDVFLICFSLISPASFENVKAKWYPEVSHHC-PNTPIILVGTKLDLRE 135

Query: 139 NKRMVE 144
           +K  +E
Sbjct: 134 DKETIE 117
>34597
          Length = 773

 Score = 55.1 bits (131), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 28/91 (30%), Positives = 50/91 (54%)
 Frame = -2

Query: 105 QETFARAKTWVKELQRQASPSIVIALAGNKADLANKRMVEYEEAQAYADDNSLLFMETSA 164
           +++F     W++ +   A+  +   + GNK D+ +KR+V  E  +A A ++S+ FMETSA
Sbjct: 715 KKSFENIVKWLRNIDEHANEDVEKMILGNKCDMTDKRVVSKERGEAIAREHSIRFMETSA 536

Query: 165 KTAMNVNDLFLAIAKKLPKSEPQNLGGAAGR 195
           K+ +N+   F  +A+ +       L   AGR
Sbjct: 535 KSNINIERAFCELAEAI-------LDKTAGR 464
>14775
          Length = 380

 Score = 54.7 bits (130), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 43/158 (27%), Positives = 61/158 (38%), Gaps = 7/158 (4%)
 Frame = -2

Query: 33  KSSLVLRFVKGQFHEYQESTIGAAFLTQSVC-------LDDTTVKFEIWDTAGQERYHSL 85
           K+ L+ R+ KG F +    TI        +C        D   V++ +WDT G E Y SL
Sbjct: 379 KTCLLRRYQKGFFMDRTMPTIAV------LCSEFNESRTDPLNVRYTLWDTGGAETYRSL 218

Query: 86  APMYYRGAQAAIVVYDITNQETFARAKTWVKELQRQASPSIVIALAGNKADLANKRMVEY 145
              ++RGAQ A++VYD+T                                          
Sbjct: 217 WVSHFRGAQVALLVYDVTC----------------------------------------- 161

Query: 146 EEAQAYADDNSLLFMETSAKTAMNVNDLFLAIAKKLPK 183
           E  QA+A      F ETS+ T  NV+ +F  IA  L +
Sbjct: 160 ERGQAFATQCGYTFFETSSVTGKNVDAVFWEIAFILAR 47
>19656
          Length = 428

 Score = 53.1 bits (126), Expect = 8e-08,   Method: Compositional matrix adjust.
 Identities = 30/103 (29%), Positives = 51/103 (49%), Gaps = 2/103 (1%)
 Frame = +3

Query: 22  KLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQSVCLDDTTVKFEIWDTAGQER 81
           K V++G+ AVGK+ L++ +    F      T+   + + +V +D   V   +WDTAGQE 
Sbjct: 117 KCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNY-SANVMVDGRPVNLGLWDTAGQED 293

Query: 82  YHSLAPMYYRGAQAAIVVYDITNQETF--ARAKTWVKELQRQA 122
           Y  L P+ Y      ++ + + +  +F   RAK W  E+    
Sbjct: 294 YDRLRPLSYPQTDVFLLCFSVASPASFENIRAK-WYPEVNHHC 419
>31291
          Length = 446

 Score = 47.0 bits (110), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 22/68 (32%), Positives = 34/68 (50%), Gaps = 1/68 (1%)
 Frame = -1

Query: 71  FEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNQETFARAKT-WVKELQRQASPSIVIA 129
            ++WDTAGQE Y  L P+ Y      ++ + + ++ +    K  W  E+ R   P + I 
Sbjct: 446 LQLWDTAGQEDYDRLRPLAYPNTDVFMLXFSLMSEASMKNVKVKWYPEI-RHHDPHVPIV 270

Query: 130 LAGNKADL 137
           L G K DL
Sbjct: 269 LVGTKLDL 246
>00552
          Length = 455

 Score = 47.0 bits (110), Expect = 6e-06,   Method: Compositional matrix adjust.
 Identities = 24/48 (50%), Positives = 30/48 (62%)
 Frame = -1

Query: 21  FKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQSVCLDDTT 68
            K+VLLG+  VGKSSL+ RFV  +F      TIG  FLT+ V +D  T
Sbjct: 443 LKVVLLGDGGVGKSSLMNRFVSNKFDAQSFHTIGVEFLTKDVVVDGET 300

 Score = 46.2 bits (108), Expect = 9e-06,   Method: Compositional matrix adjust.
 Identities = 18/46 (39%), Positives = 25/46 (54%)
 Frame = -3

Query: 73  IWDTAGQERYHSLAPMYYRGAQAAIVVYDITNQETFARAKTWVKEL 118
           IWDTAGQERY SL   +YRG    ++ + + N ++      W  E 
Sbjct: 147 IWDTAGQERYKSLRTPFYRGTDCCLLTFSVDNLKSLQSLSDWYDEF 10
>08153
          Length = 1703

 Score = 45.1 bits (105), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 33/124 (26%), Positives = 60/124 (48%), Gaps = 4/124 (3%)
 Frame = +1

Query: 20  QFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQSVCLDDTTVKFEIWDTAGQ 79
           + +++++G  A GK++++ +   G+       TIG  F  ++V  +   + F +WD  GQ
Sbjct: 82  EVRILMVGLDAAGKTTILYKLKLGEIVT-TIPTIG--FNVETV--EYKNISFTVWDVGGQ 246

Query: 80  ERYHSLAPMYYRGAQAAIVVYDITNQETFARAKTWVKELQRQASP----SIVIALAGNKA 135
           ++   L   Y++  Q  I V D  ++E    AK   +EL R  +       +I +  NK 
Sbjct: 247 DKIRPLWRHYFQNTQGLIFVVDSNDRERINEAK---EELARMLNEDDLRDAIILVFANKQ 417

Query: 136 DLAN 139
           DL N
Sbjct: 418 DLPN 429
>10862
          Length = 2896

 Score = 41.2 bits (95), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 21/73 (28%), Positives = 36/73 (49%), Gaps = 2/73 (2%)
 Frame = -3

Query: 69   VKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNQETFARAKTWVKEL--QRQASPSI 126
             +F +WD  GQ++   L   YY G Q  I V D  +++    A+  +  +   R+   +I
Sbjct: 2486 CQFNVWDVGGQDKIRPLWRHYYTGTQGLIFVVDCADRDRIDEARQELHRIINDREMRDAI 2307

Query: 127  VIALAGNKADLAN 139
            ++  A NK DL +
Sbjct: 2306 ILIFA-NKQDLPD 2271
>09827
          Length = 1201

 Score = 40.4 bits (93), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 31/122 (25%), Positives = 59/122 (48%), Gaps = 4/122 (3%)
 Frame = -3

Query: 22   KLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQSVCLDDTTVKFEIWDTAGQER 81
            +++++G  A GK++++ +   G+       TIG  F  ++V  +   + F +WD  GQ++
Sbjct: 1109 RILMVGLDAAGKTTILYKLKLGEIVT-TIPTIG--FNVETV--EYKNISFTVWDVGGQDK 945

Query: 82   YHSLAPMYYRGAQAAIVVYDITNQETFARAKTWVKELQRQASP----SIVIALAGNKADL 137
               L   Y++  Q  I V D  ++E    A+   +EL R  +       V+ +  NK DL
Sbjct: 944  IRPLWRHYFQNTQGLIFVVDSNDKERVQEAR---EELTRMLNEDELRDAVLLVFANKQDL 774

Query: 138  AN 139
             +
Sbjct: 773  PH 768
>18509
          Length = 625

 Score = 36.6 bits (83), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 21/66 (31%), Positives = 36/66 (54%)
 Frame = -3

Query: 125 SIVIALAGNKADLANKRMVEYEEAQAYADDNSLLFMETSAKTAMNVNDLFLAIAKKLPKS 184
            + + L GNK DL   R VE  + +  A+   + ++ETSAKT   V+D F  + +++ K 
Sbjct: 530 EVPMVLVGNKVDLPI-RNVEQRQGKHMAELYHIPYVETSAKTRQGVDDAFYTLVREIRKY 354

Query: 185 EPQNLG 190
           + +  G
Sbjct: 353 KERKDG 336
>10708
          Length = 2775

 Score = 36.2 bits (82), Expect = 0.012,   Method: Compositional matrix adjust.
 Identities = 13/40 (32%), Positives = 22/40 (55%)
 Frame = -2

Query: 69   VKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNQETF 108
            V+  +WDTAGQE Y  L P+ Y      ++ + I + ++ 
Sbjct: 2723 VELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSL 2604
>06994
          Length = 429

 Score = 34.3 bits (77), Expect = 0.044,   Method: Compositional matrix adjust.
 Identities = 15/28 (53%), Positives = 22/28 (78%)
 Frame = +3

Query: 20 QFKLVLLGESAVGKSSLVLRFVKGQFHE 47
          ++KLV+LG   VGKS+L ++FV+G F E
Sbjct: 54 EYKLVVLGSGGVGKSALTVQFVQGIFVE 137
>33605
          Length = 888

 Score = 33.5 bits (75), Expect = 0.068,   Method: Compositional matrix adjust.
 Identities = 22/93 (23%), Positives = 41/93 (44%)
 Frame = +1

Query: 20  QFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQSVCLDDTTVKFEIWDTAGQ 79
           + +L++LG    GK++++ +F  G+  +    T+G    T    L+    K  +WD  GQ
Sbjct: 496 EVRLLMLGLDNAGKTTILKKF-NGEDIDTISPTLGFNIKT----LEHRGFKLNVWDVGGQ 660

Query: 80  ERYHSLAPMYYRGAQAAIVVYDITNQETFARAK 112
           +   S    Y+      + V D  ++   A  K
Sbjct: 661 QSLRSYWRNYFESTDGLVWVVDSADRMRIADCK 759
>34156
          Length = 348

 Score = 29.6 bits (65), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 16/53 (30%), Positives = 30/53 (56%)
 Frame = -1

Query: 20  QFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQSVCLDDTTVKFE 72
           +F L+++GES +GKS+LV        +  +     +  + Q+V +D +TV+ E
Sbjct: 198 EFTLMVVGESGLGKSTLVNSLFLTDLYPERHIPSASEKIQQTVKIDASTVEIE 40
>19310
          Length = 784

 Score = 27.3 bits (59), Expect(2) = 1.5,   Method: Compositional matrix adjust.
 Identities = 15/36 (41%), Positives = 19/36 (52%)
 Frame = -2

Query: 8   RPNGQPQASKICQFKLVLLGESAVGKSSLVLRFVKG 43
           RP G+   S +C F L L G  + G + LVL  V G
Sbjct: 459 RPGGR---SSVCGFSLRLCGPQSCGHTWLVLWXVLG 361

 Score = 20.0 bits (40), Expect(2) = 1.5,   Method: Compositional matrix adjust.
 Identities = 8/18 (44%), Positives = 12/18 (66%)
 Frame = -3

Query: 68  TVKFEIWDTAGQERYHSL 85
            V ++++DT   ERY SL
Sbjct: 302 VVSWKLYDTGYTERYLSL 249
>30516
          Length = 606

 Score = 28.5 bits (62), Expect = 2.3,   Method: Compositional matrix adjust.
 Identities = 17/59 (28%), Positives = 25/59 (42%)
 Frame = +2

Query: 20  QFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQSVCLDDTTVKFEIWDTAG 78
           + ++VLLG++  GKSSL    +          T      TQ  C D      ++ DT G
Sbjct: 170 RLRVVLLGKTGSGKSSLGNTLLGKDTFRVMPGTSSGTKDTQRECADRFGTMIQVTDTPG 346
>25991
          Length = 847

 Score = 28.1 bits (61), Expect = 3.0,   Method: Compositional matrix adjust.
 Identities = 24/109 (22%), Positives = 48/109 (44%), Gaps = 2/109 (1%)
 Frame = -1

Query: 18  ICQFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLT--QSVCLDDTTVKFEIWD 75
           + + K  L+GE+  G  ++   FV+G+F +  +ST      T  +   LD+  V++   +
Sbjct: 358 LIRLKSSLVGETDPGDGTVAEGFVRGRFKDESKSTXFNKLWTPEEQKRLDELLVQYPPEE 179

Query: 76  TAGQERYHSLAPMYYRGAQAAIVVYDITNQETFARAKTWVKELQRQASP 124
              +           R  + A    D T Q+  +R + + ++L+R   P
Sbjct: 178 VEAR-----------RWRKIAAAFGDRTPQQIASRVQKYFEKLERNKLP 65
>25795
          Length = 663

 Score = 26.9 bits (58), Expect = 6.7,   Method: Compositional matrix adjust.
 Identities = 13/44 (29%), Positives = 22/44 (50%)
 Frame = -1

Query: 129 ALAGNKADLANKRMVEYEEAQAYADDNSLLFMETSAKTAMNVND 172
            L+GN +D  N+ + E  +      DNS +F+      A NV++
Sbjct: 210 CLSGNNSDFWNRGLSEGVQELGSVTDNSPVFLRRPR*KARNVDE 79
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|23510275|ref|NP_700451.1| eukaryotic translation
initiation factor 2C, 3 [Mus musculus]
         (860 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

19404                                                                 302   4e-82
06972                                                                 272   5e-73
02516                                                                 112   7e-25
06326                                                                  61   2e-09
22922                                                                  49   1e-05
01764                                                                  40   0.003
07448                                                                  32   1.1  
34844                                                                  30   2.8  
03817                                                                  30   5.2  
>19404
          Length = 576

 Score =  302 bits (773), Expect = 4e-82,   Method: Compositional matrix adjust.
 Identities = 150/192 (78%), Positives = 166/192 (86%), Gaps = 6/192 (3%)
 Frame = +1

Query: 526 KTPVYAEVKRVGDTLLGMATQCVQVKNVIKTSPQTLSNLCLKINVKLGGINNILVPHQRP 585
           KTPVYAEVKRVGD + G+ATQCVQ KNV KT+PQTLSNLCLKINVKLGG+N+IL+P  RP
Sbjct: 1   KTPVYAEVKRVGDIMFGLATQCVQSKNVNKTTPQTLSNLCLKINVKLGGVNSILLPSIRP 180

Query: 586 SVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPSRYCATVRVQRPRQEIIQDLAS 645
           +VF++PVIFLGADVTHPPAGD  KPSIAAVVGSMDAHPSRY A VRVQ  RQE+I +LA+
Sbjct: 181 AVFREPVIFLGADVTHPPAGDSSKPSIAAVVGSMDAHPSRYAAAVRVQEHRQEVIYELAT 360

Query: 646 MVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFR-----QVLYYELLAIREACISLEKDYQ 700
           MVRELLIQFY+STRFKPTRIIFYRDGVSEGQF      QVL +EL AIREAC  LE DY+
Sbjct: 361 MVRELLIQFYRSTRFKPTRIIFYRDGVSEGQFHASTYLQVLSHELRAIREACTKLEGDYR 540

Query: 701 PG-ITYIVVQKR 711
           PG  T+IVVQKR
Sbjct: 541 PGNTTFIVVQKR 576
>06972
          Length = 1038

 Score =  272 bits (695), Expect = 5e-73,   Method: Compositional matrix adjust.
 Identities = 125/158 (79%), Positives = 137/158 (86%)
 Frame = +1

Query: 703 ITYIVVQKRHHTRLFCADRTERVGRSGNIPAGTTVDTDITHPYEFDFYLCSHAGIQGTSR 762
           IT+IVVQKRHHTRLFCA++ E+ G+SGNIPAGTTVD  ITHP EFDFYLCSH GIQGT R
Sbjct: 4   ITFIVVQKRHHTRLFCAEKKEQSGKSGNIPAGTTVDVGITHPTEFDFYLCSHQGIQGTXR 183

Query: 763 PSHYHVLWDDNFFTADELQLLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKE 822
           PSHYHVLWDDN F +DELQ LTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLV+KE
Sbjct: 184 PSHYHVLWDDNHFDSDELQCLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVEKE 363

Query: 823 HDSAEGSHVSGQSNGRDPQALAKAVQIHQDTLRTMYFA 860
           HDS EGSH SG S  R P A+A+A+ +H DT + MYFA
Sbjct: 364 HDSGEGSHQSGSSEDRTPGAMARAITVHADTKKVMYFA 477
>02516
          Length = 2764

 Score =  112 bits (280), Expect = 7e-25,   Method: Compositional matrix adjust.
 Identities = 108/411 (26%), Positives = 181/411 (44%), Gaps = 35/411 (8%)
 Frame = +1

Query: 437  DMRGKQFHTGVEIKMWAIACFATQRQCREEILKGFTDQLRKISKDAGMPIQGQPCFCKYA 496
            DMRGK+    V ++ W +     Q++  ++  K     L K+    GM I   P   +  
Sbjct: 1471 DMRGKKMVLAVPLQRWLLV---VQKRSTDKA-KDLAGILAKVGPPMGMNI-APPRMVQID 1635

Query: 497  QG-ADSVEPMFRHLKNTYSG-LQLIIVILPG-KTPVYAEVKRVGDTLLGMATQCVQVKNV 553
            Q   DS     R  +N   G  QL++ +L   K   Y  +K+     + +A+Q V  K +
Sbjct: 1636 QDRNDSYIHALR--ENIREGETQLVVCVLSNNKKDRYDAIKKYCCIDMPVASQMVTDKTL 1809

Query: 554  IKTSPQTLSNLCLKI----NVKLGGINNILVPHQRPSVFQQPV-----IFLGADVTHPPA 604
              ++ Q L ++  KI    N KLGG+           V+  P+     + +G D  H  A
Sbjct: 1810 --SNKQRLMSVATKIAIQMNCKLGGV-----------VWVCPIPLVNTMIVGIDTYHDSA 1950

Query: 605  GDGKKPSIAAVVGSMDAHPSRYCATVRVQRPRQEIIQDLASMVRELLIQFYKSTRFK-PT 663
              G+  S+  +V ++++  SRY +T   Q    E+   L   +   L  + +    K P 
Sbjct: 1951 VRGQ--SVGGIVATVNSDYSRYFSTCTFQMRHLELQDKLYFSIIACLKAYGRENNNKYPD 2124

Query: 664  RIIFYRDGVSEGQFRQVLYYELLAIREACISLEK--DYQPGITYIVVQKRHHTRLF---- 717
            +++ +RDGV +GQ + V  +E+  +R A     +  D    + YI+V+KR + R F    
Sbjct: 2125 KVVVFRDGVGDGQLQLVYEHEIPQVRRALNKCAERFDMTIKLAYIIVKKRTNARFFQEGV 2304

Query: 718  ----------------CADRTERVGRSGNIPAGTTVDTDITHPYEFDFYLCSHAGIQGTS 761
                                  +     N   GT +D   T P  FDF+L S +   GT 
Sbjct: 2305 IMESGPGGARGGRGGGGGAGGGQRRGLTNPGPGTIIDNVATKPTWFDFFLISQSVRDGTV 2484

Query: 762  RPSHYHVLWDDNFFTADELQLLTYQLCHTYVRCTRSVSIPAPAYYAHLVAF 812
             P+H++V++D+    ++  Q + Y+LCH Y     ++ +PAP  YAH +AF
Sbjct: 2485 SPTHFNVIFDELDIKSEYYQRMAYKLCHMYYNWQGTIRVPAPCMYAHKLAF 2637
>06326
          Length = 486

 Score = 60.8 bits (146), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 50/169 (29%), Positives = 81/169 (47%), Gaps = 8/169 (4%)
 Frame = -3

Query: 562 SNLCLKINVKLGGINNILVPHQRPSVFQQPV---IFLGADVTHPPAGDGKKPSIAAVVGS 618
           + + +++N KL G          P + + PV   + +G DV H  +   K  S  A+V +
Sbjct: 475 TKVVIQMNAKLMGA---------PWMIELPVRGLMTVGFDVCH--SSKDKNKSYGALVAT 329

Query: 619 MDAHPS-RYCATVRVQRPRQEIIQDLASMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQF 677
           MD   S RY ++V      QE+   ++  +   L  + K     P RI+F+RDGV +GQ 
Sbjct: 328 MDLKLSTRYYSSVTEHMKGQELSNQMSVNMTCALKAYRKHHGTLPERILFFRDGVGDGQL 149

Query: 678 RQVLYYELLAIREAC----ISLEKDYQPGITYIVVQKRHHTRLFCADRT 722
            QV+  E+  +++       S  KD    + +IVV KR +TR F  +R 
Sbjct: 148 EQVVNTEVKYLKDQLDQIYKSAGKDVGCRMAFIVVSKRINTRYFARNRN 2
>22922
          Length = 970

 Score = 48.5 bits (114), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 37/128 (28%), Positives = 63/128 (49%), Gaps = 4/128 (3%)
 Frame = +3

Query: 562 SNLCLKINVKLGGINNILVPHQRPSVFQQPV---IFLGADVTHPPAGDGKKPSIAAVVGS 618
           + + +++N KL G          P + + PV   + +G DV H  +   K  S  A+V +
Sbjct: 12  TKVVIQMNAKLMG---------APWMIELPVRGLMTVGFDVCH--SSKDKNKSYGAIVAT 158

Query: 619 MDAHPS-RYCATVRVQRPRQEIIQDLASMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQF 677
           MD   S RY ++V      QE+   ++  +   L  + ++    P RI+F+RDGV +GQ 
Sbjct: 159 MDLKLSTRYYSSVTEHMKGQELSNQMSVNMTCALKAYRENHGSLPERILFFRDGVGDGQL 338

Query: 678 RQVLYYEL 685
            QV+  E+
Sbjct: 339 AQVVNTEV 362

 Score = 47.4 bits (111), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 21/55 (38%), Positives = 35/55 (63%)
 Frame = +2

Query: 758 QGTSRPSHYHVLWDDNFFTADELQLLTYQLCHTYVRCTRSVSIPAPAYYAHLVAF 812
           +GT  P+ Y+V+ D+    AD+LQ+L+Y++ H Y   + +  +PA   YAH +AF
Sbjct: 569 KGTVSPTSYNVIQDNMGLDADKLQMLSYKMTHLYYNWSGTCRVPAVCQYAHKLAF 733
>01764
          Length = 441

 Score = 40.4 bits (93), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 23/84 (27%), Positives = 38/84 (45%)
 Frame = -3

Query: 757 IQGTSRPSHYHVLWDDNFFTADELQLLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARY 816
           +     P  ++V++D+    ++  Q + Y+LCH Y     ++ +PAP  YAH +AF    
Sbjct: 292 VTAQCHPLTFNVIFDELDIKSEYYQRMAYKLCHMYYNWQGTIRVPAPCMYAHKLAF---- 125

Query: 817 HLVDKEHDSAEGSHVSGQSNGRDP 840
                         + GQS  RDP
Sbjct: 124 --------------LVGQSLHRDP 95
>07448
          Length = 624

 Score = 32.0 bits (71), Expect = 1.1,   Method: Composition-based stats.
 Identities = 32/128 (25%), Positives = 56/128 (43%), Gaps = 17/128 (13%)
 Frame = +1

Query: 325 HLPCLQVGQEQKHTYLPLEVCNIVAGQRCI------KKLTDNQTSTMIKATAR-----SA 373
           H+P   + QEQ + Y+  +  +++ G+ C       K+   + T+ + K+  R       
Sbjct: 22  HVPSTPLSQEQVNLYVYFDFTSLITGEACPSLWL*HKRWLTHITAGLKKSFERVPLKQKV 201

Query: 374 PDRQEEISRLVRSANYETDPFVQEFQLKVRDEMAHVTGRVLPA------PMLQYGGRNRT 427
           P  ++E SRL RS   + D    E ++     +   T   LP+       ML    R+ T
Sbjct: 202 PCFKDEDSRLWRSFTVDDDCLSVEARVHAASVLTXGTNHWLPSCGXDADTMLSV--RSWT 375

Query: 428 VATPSHGV 435
           +ATP+  V
Sbjct: 376 IATPTSXV 399
>34844
          Length = 901

 Score = 30.4 bits (67), Expect = 2.8,   Method: Compositional matrix adjust.
 Identities = 13/40 (32%), Positives = 22/40 (55%)
 Frame = -2

Query: 547 CVQVKNVIKTSPQTLSNLCLKINVKLGGINNILVPHQRPS 586
           C+  + VI+TS    + +C  I   LGG+NN+ +    P+
Sbjct: 468 CMNFQRVIRTSLSHFTCICALIFASLGGLNNVYIALSIPA 349
>03817
          Length = 1800

 Score = 29.6 bits (65), Expect = 5.2,   Method: Composition-based stats.
 Identities = 12/30 (40%), Positives = 15/30 (50%)
 Frame = -2

Query: 763  PSHYHVLWDDNFFTADELQLLTYQLCHTYV 792
            P +YH+ WD  FF       L YQ C  Y+
Sbjct: 1757 PGYYHIYWDYIFFI-----FLYYQTCFVYI 1683
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6680722|ref|NP_031506.1| ADP-ribosylation factor 5
[Mus musculus]
         (180 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

09827                                                                 299   4e-82
08153                                                                 290   2e-79
10862                                                                 159   5e-61
33605                                                                 103   3e-26
11378                                                                  99   1e-21
18208                                                                  99   1e-21
32860                                                                  91   5e-20
06991                                                                  74   5e-14
19506                                                                  69   9e-13
18949                                                                  67   3e-12
15662                                                                  59   1e-09
34468                                                                  46   7e-06
11965                                                                  45   2e-05
14775                                                                  40   4e-04
13750                                                                  40   4e-04
29196                                                                  39   8e-04
08428                                                                  38   0.002
33794                                                                  36   0.011
35581                                                                  35   0.014
33374                                                                  35   0.020
26083                                                                  35   0.020
07465                                                                  33   0.071
13901                                                                  33   0.084
33380                                                                  31   0.30 
26536                                                                  31   0.31 
05468                                                                  30   0.46 
08444                                                                  29   1.1  
11257                                                                  28   1.7  
29881                                                                  27   3.1  
17511                                                                  27   5.8  
34359                                                                  27   5.8  
10691                                                                  27   6.0  
05400                                                                  26   6.9  
01972                                                                  26   9.3  
22540                                                                  26   9.3  
>09827
          Length = 1201

 Score =  299 bits (766), Expect = 4e-82,   Method: Compositional matrix adjust.
 Identities = 143/180 (79%), Positives = 160/180 (88%), Gaps = 3/180 (1%)
 Frame = -3

Query: 1    MGLTVSALFSRI---FGKKQMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVE 57
            MG     +FS +   FGKK MRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVE
Sbjct: 1172 MGNAFQKIFSGLSFMFGKKDMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVE 993

Query: 58   YKNICFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVQESADELQKMLQEDELR 117
            YKNI FTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSND+ERVQE+ +EL +ML EDELR
Sbjct: 992  YKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDKERVQEAREELTRMLNEDELR 813

Query: 118  DAVLLVFANKQDMPNAMPVSELTDKLGLQHLRSRTWYVQATCATQGTGLYDGLDWLSHEL 177
            DAVLLVFANKQD+P+AM  +E+T+KLGL  LR+RTWY+Q+TCAT G GLY+GLDWLS++L
Sbjct: 812  DAVLLVFANKQDLPHAMATAEITEKLGLHGLRNRTWYIQSTCATTGDGLYEGLDWLSNQL 633
>08153
          Length = 1703

 Score =  290 bits (743), Expect = 2e-79,   Method: Compositional matrix adjust.
 Identities = 137/180 (76%), Positives = 156/180 (86%)
 Frame = +1

Query: 1   MGLTVSALFSRIFGKKQMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKN 60
           MG  VS LF  +FGKK++RILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKN
Sbjct: 37  MGGFVS-LFKNLFGKKEVRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKN 213

Query: 61  ICFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVQESADELQKMLQEDELRDAV 120
           I FTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRER+ E+ +EL +ML ED+LRDA+
Sbjct: 214 ISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERINEAKEELARMLNEDDLRDAI 393

Query: 121 LLVFANKQDMPNAMPVSELTDKLGLQHLRSRTWYVQATCATQGTGLYDGLDWLSHELSKR 180
           +LVFANKQD+PNA   SE+T  LGL +L+ R WY+QATCAT G G+Y+GL+WLS  L  +
Sbjct: 394 ILVFANKQDLPNAYSASEVTAHLGLANLKGRKWYMQATCATSGDGMYEGLEWLSTTLKHK 573
>10862
          Length = 2896

 Score =  159 bits (402), Expect(2) = 5e-61,   Method: Compositional matrix adjust.
 Identities = 69/112 (61%), Positives = 88/112 (78%)
 Frame = -3

Query: 63   FTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVQESADELQKMLQEDELRDAVLL 122
            F VWDVGGQDKIRPLWRHY+  TQGLIFVVD  DR+R+ E+  EL +++ + E+RDA++L
Sbjct: 2480 FNVWDVGGQDKIRPLWRHYYTGTQGLIFVVDCADRDRIDEARQELHRIINDREMRDAIIL 2301

Query: 123  VFANKQDMPNAMPVSELTDKLGLQHLRSRTWYVQATCATQGTGLYDGLDWLS 174
            +FANKQD+P+AM   E+ +KLGL  LR R WYVQ +CAT G GL +GL WL+
Sbjct: 2300 IFANKQDLPDAMKPHEIQEKLGLTRLRDRNWYVQPSCATTGDGLCEGLTWLT 2145

 Score = 91.7 bits (226), Expect(2) = 5e-61,   Method: Compositional matrix adjust.
 Identities = 41/59 (69%), Positives = 52/59 (88%)
 Frame = -1

Query: 3    LTVSALFSRIFGKKQMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNI 61
            +T+  L S+IFG K+MRILM+GLDAAGKTT+LYK+KLG+ VT IPT+GFNVETV +KN+
Sbjct: 2659 ITMGKLLSKIFGNKEMRILMLGLDAAGKTTLLYKMKLGQSVTXIPTVGFNVETVSFKNV 2483
>33605
          Length = 888

 Score =  103 bits (257), Expect(2) = 3e-26,   Method: Compositional matrix adjust.
 Identities = 46/88 (52%), Positives = 66/88 (75%)
 Frame = +1

Query: 15  KKQMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNICFTVWDVGGQDKI 74
           +K++R+LM+GLD AGKTTIL K    +I T  PT+GFN++T+E++     VWDVGGQ  +
Sbjct: 490 EKEVRLLMLGLDNAGKTTILKKFNGEDIDTISPTLGFNIKTLEHRGFKLNVWDVGGQQSL 669

Query: 75  RPLWRHYFQNTQGLIFVVDSNDRERVQE 102
           R  WR+YF++T GL++VVDS DR R+ +
Sbjct: 670 RSYWRNYFESTDGLVWVVDSADRMRIAD 753

 Score = 31.2 bits (69), Expect(2) = 3e-26,   Method: Compositional matrix adjust.
 Identities = 16/39 (41%), Positives = 22/39 (56%)
 Frame = +3

Query: 107 LQKMLQEDELRDAVLLVFANKQDMPNAMPVSELTDKLGL 145
           LQ +L E+ L  A LLVFAN +  P A+   E+   + L
Sbjct: 765 LQGLLVEERLAGATLLVFANSRTCPGALXSQEIQQAMDL 881
>11378
          Length = 1688

 Score = 98.6 bits (244), Expect = 1e-21,   Method: Compositional matrix adjust.
 Identities = 48/134 (35%), Positives = 80/134 (59%)
 Frame = +3

Query: 15  KKQMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNICFTVWDVGGQDKI 74
           KK  +++ +GLD AGKTT+L+ LK  ++   +PT+    E +    + FT +D+GG  + 
Sbjct: 315 KKSGKLVFLGLDNAGKTTLLHMLKDDKMAQHVPTLHPTSEELSMGGMRFTTFDLGGHRQA 494

Query: 75  RPLWRHYFQNTQGLIFVVDSNDRERVQESADELQKMLQEDELRDAVLLVFANKQDMPNAM 134
           R +W+ YF    G++F+VD +DRER+ E+  EL  ++ ++++ +A +LV  NK D P A 
Sbjct: 495 RRVWKDYFPAVDGIVFLVDVHDRERLVEAKAELDSLMTDEQVANAPILVLGNKIDKPGAA 674

Query: 135 PVSELTDKLGLQHL 148
              E+    GL  L
Sbjct: 675 SEEEIRHWFGLNSL 716
>18208
          Length = 458

 Score = 98.6 bits (244), Expect = 1e-21,   Method: Compositional matrix adjust.
 Identities = 42/89 (47%), Positives = 66/89 (74%)
 Frame = -1

Query: 16  KQMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNICFTVWDVGGQDKIR 75
           +++RIL++GLD AGKTT+L +L   +     PT GFN+++V+ K     VWD+GGQ +IR
Sbjct: 305 RELRILLLGLDNAGKTTLLKQLASEDPSHITPTQGFNIKSVQSKGFKLNVWDIGGQRRIR 126

Query: 76  PLWRHYFQNTQGLIFVVDSNDRERVQESA 104
           P W++YF+NT  LI+V+DS+D +R++E+ 
Sbjct: 125 PYWKNYFENTDLLIYVIDSSDTKRMEETG 39
>32860
          Length = 330

 Score = 90.5 bits (223), Expect(2) = 5e-20,   Method: Compositional matrix adjust.
 Identities = 38/89 (42%), Positives = 58/89 (65%)
 Frame = +2

Query: 78  WRHYFQNTQGLIFVVDSNDRERVQESADELQKMLQEDELRDAVLLVFANKQDMPNAMPVS 137
           W  Y+ N++ +I V+DS DRER+  + +EL +ML  +ELR A LLVFANKQD+   M  +
Sbjct: 8   WNTYYSNSEFIIMVIDSTDRERLSITKEELCRMLATEELRXAALLVFANKQDIKGCMSAA 187

Query: 138 ELTDKLGLQHLRSRTWYVQATCATQGTGL 166
           E++ +L L  ++   W++QA C   G G+
Sbjct: 188 EISXQLNLTSVKDHVWHIQACCGLTGEGV 274

 Score = 23.1 bits (48), Expect(2) = 5e-20,   Method: Compositional matrix adjust.
 Identities = 7/16 (43%), Positives = 12/16 (75%)
 Frame = +1

Query: 165 GLYDGLDWLSHELSKR 180
           GLY GL+W++  + +R
Sbjct: 271 GLYQGLEWITSHIRRR 318
>06991
          Length = 1860

 Score = 73.6 bits (179), Expect = 5e-14,   Method: Compositional matrix adjust.
 Identities = 32/69 (46%), Positives = 51/69 (73%)
 Frame = -2

Query: 111  LQEDELRDAVLLVFANKQDMPNAMPVSELTDKLGLQHLRSRTWYVQATCATQGTGLYDGL 170
            L+EDEL+ ++L+VFANKQD+  AM V+E+ + LGL  L++R + +  T A +G GL + +
Sbjct: 1859 LEEDELKKSILMVFANKQDIEGAMTVTEVANSLGLPGLKNRKYQIFKTSAVKGEGLDEAM 1680

Query: 171  DWLSHELSK 179
            +WLS+ L+K
Sbjct: 1679 EWLSNSLTK 1653
>19506
          Length = 421

 Score = 69.3 bits (168), Expect = 9e-13,   Method: Compositional matrix adjust.
 Identities = 32/59 (54%), Positives = 44/59 (74%)
 Frame = -3

Query: 3   LTVSALFSRIFGKKQMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNI 61
           L + +    +F +K + ++  GLDAAGKTT+LY LKLGE+VTTIPTIGFNVET++   +
Sbjct: 179 LKMGSALCTLFRQKPVTVIYFGLDAAGKTTLLYNLKLGEVVTTIPTIGFNVETLDMNRV 3
>18949
          Length = 414

 Score = 67.4 bits (163), Expect = 3e-12,   Method: Compositional matrix adjust.
 Identities = 30/83 (36%), Positives = 49/83 (59%)
 Frame = +3

Query: 47  PTIGFNVETVEYKNICFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVQESADE 106
           PT     E +    + FT +D+GG  + R +W+ YF    G++F+VD +D ER+ E+  E
Sbjct: 15  PTGLPTSEELSMGGMTFTTFDLGGHRQARRVWKDYFPAVDGIVFIVDVHDTERITEAKAE 194

Query: 107 LQKMLQEDELRDAVLLVFANKQD 129
           L  +L++D++ D  +LV  NK D
Sbjct: 195 LDSLLRDDQIADIPVLVLGNKMD 263
>15662
          Length = 455

 Score = 58.9 bits (141), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 27/76 (35%), Positives = 44/76 (57%)
 Frame = +2

Query: 73  KIRPLWRHYFQNTQGLIFVVDSNDRERVQESADELQKMLQEDELRDAVLLVFANKQDMPN 132
           + R +W+ YF    G++F+VD +DRER  E+  EL  ++ ++++ +A +LV  NK D P 
Sbjct: 2   QARRVWKDYFPAVDGIVFLVDVHDRERFVEAKAELDSLMTDEQVANAPILVLGNKIDKPG 181

Query: 133 AMPVSELTDKLGLQHL 148
           A    E+    GL  L
Sbjct: 182 AASEDEIRHWFGLHSL 229
>34468
          Length = 1502

 Score = 46.2 bits (108), Expect = 7e-06,   Method: Compositional matrix adjust.
 Identities = 24/85 (28%), Positives = 47/85 (55%), Gaps = 6/85 (7%)
 Frame = +1

Query: 15  KKQMRILMVGLDAAGKTTILYKLKLGEIV-TTIPTIGFNVET----VEYKNICFTVWDVG 69
           ++  +I+++G    GKT + Y+  LG+    T  TIG +       V+ +++   +WD  
Sbjct: 487 RRIFKIIVIGDSNVGKTCLTYRFCLGKFPDKTEATIGVDFREKSIQVDSEHLKLQLWDTA 666

Query: 70  GQDKIR-PLWRHYFQNTQGLIFVVD 93
           GQ++ R  + +HY++N   ++FV D
Sbjct: 667 GQERFRKSMVQHYYRNVHAVVFVYD 741
>11965
          Length = 3256

 Score = 45.1 bits (105), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 35/129 (27%), Positives = 56/129 (43%), Gaps = 15/129 (11%)
 Frame = +1

Query: 44  TTIPTIGFNVETVEYKNICFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRE----- 98
           T + T G       +KN+ F ++DVGGQ   R  W H F++   +IF V  ++ +     
Sbjct: 133 TRVKTTGIVEVHFSFKNLNFKLFDVGGQRSERKKWIHCFEDVTAIIFCVAMSEYDQVLHE 312

Query: 99  -----RVQESADELQKMLQEDELRDAVLLVFANKQDM-PNAMPVSELT----DKLGLQHL 148
                R+QES      +       D  +++F NK+D+    +  S LT    +  G Q  
Sbjct: 313 DETTNRMQESLKLFDSICNNKWFTDTSIILFLNKKDLFEEKIKKSPLTVCFPEYTGKQTY 492

Query: 149 RSRTWYVQA 157
                Y+QA
Sbjct: 493 EEVAAYIQA 519
>14775
          Length = 380

 Score = 40.4 bits (93), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 23/70 (32%), Positives = 36/70 (51%), Gaps = 6/70 (8%)
 Frame = -2

Query: 30  KTTILYKLKLGEIV-TTIPTIG-----FNVETVEYKNICFTVWDVGGQDKIRPLWRHYFQ 83
           KT +L + + G  +  T+PTI      FN    +  N+ +T+WD GG +  R LW  +F+
Sbjct: 379 KTCLLRRYQKGFFMDRTMPTIAVLCSEFNESRTDPLNVRYTLWDTGGAETYRSLWVSHFR 200

Query: 84  NTQGLIFVVD 93
             Q  + V D
Sbjct: 199 GAQVALLVYD 170
>13750
          Length = 503

 Score = 40.4 bits (93), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 29/114 (25%), Positives = 53/114 (46%), Gaps = 6/114 (5%)
 Frame = -2

Query: 30  KTTILYKLKLGEIV-TTIPTIG-----FNVETVEYKNICFTVWDVGGQDKIRPLWRHYFQ 83
           KT +L + + G  +  T+PTI      FN    +  N+ +T+WD GG +  R LW  +F+
Sbjct: 502 KTCLLRRYQKGFFMDRTMPTIAVLCSEFNESRTDPLNVRYTLWDTGGAETYRSLWVSHFR 323

Query: 84  NTQGLIFVVDSNDRERVQESADELQKMLQEDELRDAVLLVFANKQDMPNAMPVS 137
             Q  + V D         +    +K L ++ + +A ++   +K D+     +S
Sbjct: 322 GAQVALLVYDVTCEWSFLTATTVWRKALMKN-IPEAQVIFVGSKTDLEENRVIS 164
>29196
          Length = 431

 Score = 39.3 bits (90), Expect = 8e-04,   Method: Compositional matrix adjust.
 Identities = 19/62 (30%), Positives = 35/62 (56%)
 Frame = -2

Query: 59  KNICFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVQESADELQKMLQEDELRD 118
           KN+ F ++DVGGQ   R  W H F++   +IF V  ++ ++V    +   +M +  +L D
Sbjct: 229 KNLNFKLFDVGGQRSERKKWIHCFEDVTAIIFCVAMSEYDQVLHEDETTNRMQESLKLFD 50

Query: 119 AV 120
           ++
Sbjct: 49  SI 44
>08428
          Length = 1109

 Score = 38.1 bits (87), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 29/120 (24%), Positives = 54/120 (45%), Gaps = 5/120 (4%)
 Frame = -3

Query: 16   KQMRILMVGLDAAGKTTILYKLKLGEI-VTTIPTIGFNVET----VEYKNICFTVWDVGG 70
            + +++ ++G    GK++I+ +   G    +   TIG +  +    V+     F +WD  G
Sbjct: 1074 RDVKVCLLGDSGVGKSSIVLRFVTGSYRPSQESTIGASFMSKSLVVDGAGYRFQIWDTAG 895

Query: 71   QDKIRPLWRHYFQNTQGLIFVVDSNDRERVQESADELQKMLQEDELRDAVLLVFANKQDM 130
            Q+K R L   Y++     + V D   R R  +S     + L+     + VL +  NK D+
Sbjct: 894  QEKFRALAPMYYRGAAAAVIVYDVT-RPRTFKSVKSWIQELRSFGPPNIVLAIAGNKCDL 718
>33794
          Length = 779

 Score = 35.8 bits (81), Expect = 0.011,   Method: Compositional matrix adjust.
 Identities = 25/93 (26%), Positives = 41/93 (44%), Gaps = 12/93 (12%)
 Frame = -1

Query: 48  TIGFNVETV--EYKNICFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDR-------- 97
           T+ +   T+  E K +   +WD  GQ +   + R Y +  QG+I V D  ++        
Sbjct: 695 TVAYKTTTILLEGKRVKLQIWDTSGQGRFCTIIRSYSRGAQGIILVYDITNKWSFDGIDR 516

Query: 98  --ERVQESADELQKMLQEDELRDAVLLVFANKQ 128
             + V+E A  + K+L  + L  A     A KQ
Sbjct: 515 WLKEVEEHAPGIPKVLVGNRLHLAYKRQVAAKQ 417
>35581
          Length = 364

 Score = 35.4 bits (80), Expect = 0.014,   Method: Compositional matrix adjust.
 Identities = 21/95 (22%), Positives = 45/95 (47%), Gaps = 6/95 (6%)
 Frame = +2

Query: 18  MRILMVGLDAAGKTTILYKLK----LGEIVTTIPTIGFNVETVEYKNICFTV--WDVGGQ 71
            + +++G    GKT +L +L     L   +T++ T            +  +V  WD  GQ
Sbjct: 47  FKCVLLGDAGVGKTCLLNRLATDKFLDSPLTSLTTASLLTTVTLTSGVMASVDLWDTAGQ 226

Query: 72  DKIRPLWRHYFQNTQGLIFVVDSNDRERVQESADE 106
           ++ R L   Y+++T+ ++ V D+  + ++ +  D 
Sbjct: 227 ERYRSLTSSYYRDTKAVLIVYDAEHKLKLTDWTDR 331
>33374
          Length = 489

 Score = 34.7 bits (78), Expect = 0.020,   Method: Compositional matrix adjust.
 Identities = 20/72 (27%), Positives = 33/72 (45%)
 Frame = +1

Query: 61  ICFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVQESADELQKMLQEDELRDAV 120
           + F +WD  GQ++   L   Y++  Q  I V D  +++     A    K LQ     + V
Sbjct: 175 VKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNQDTFGR-AKTWVKELQRQASPNIV 351

Query: 121 LLVFANKQDMPN 132
           + +  NK D+ N
Sbjct: 352 IALAGNKADLAN 387
>26083
          Length = 432

 Score = 34.7 bits (78), Expect = 0.020,   Method: Compositional matrix adjust.
 Identities = 23/117 (19%), Positives = 55/117 (47%), Gaps = 5/117 (4%)
 Frame = +1

Query: 16  KQMRILMVGLDAAGKTTILYKLKLGEIVTTI-PTIGFNVET----VEYKNICFTVWDVGG 70
           ++ +++ +G  + GKT+++ +        T   TIG +  +    +E + I   +WD  G
Sbjct: 73  RKFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTIRLQLWDTAG 252

Query: 71  QDKIRPLWRHYFQNTQGLIFVVDSNDRERVQESADELQKMLQEDELRDAVLLVFANK 127
           Q++ R L   Y +++   + V D  +     +++  +  +  E    D ++++  NK
Sbjct: 253 QERFRSLIPSYIRDSSVAVVVYDITNANSFHQTSKWIDDVRTE-RGSDVIIMLVGNK 420
>07465
          Length = 1103

 Score = 33.1 bits (74), Expect = 0.071,   Method: Compositional matrix adjust.
 Identities = 23/97 (23%), Positives = 46/97 (47%), Gaps = 5/97 (5%)
 Frame = +3

Query: 59  KNICFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVQESADELQKMLQEDELRD 118
           +++   +WD  GQ++   + + Y++  Q  +    + DR+  +  A E  K   EDE+ +
Sbjct: 339 EDVRLMLWDTAGQEEFDAITKAYYRGAQACVLAFSTVDRDSFE--ALETWKRKVEDEVGE 512

Query: 119 AVLLVFANKQDMPNAMPV-----SELTDKLGLQHLRS 150
             +++  NK D+ +   V       L  KL L+  R+
Sbjct: 513 IGMVIVQNKIDLIDDAVVRPEEAENLAKKLRLRFYRT 623
>13901
          Length = 962

 Score = 32.7 bits (73), Expect = 0.084,   Method: Compositional matrix adjust.
 Identities = 18/100 (18%), Positives = 44/100 (44%), Gaps = 14/100 (14%)
 Frame = -3

Query: 18  MRILMVGLDAAGKTTIL-----------YKLKLGEIVTTIPTIGFNVETVEYKNIC---F 63
            +++++G    GKT+ +           YK+ +G        + F ++ + + + C    
Sbjct: 285 FKVIIIGDPTVGKTSFVQRYVNDSFRRDYKMTIG--------VDFALKVIRWSDKCNIKL 130

Query: 64  TVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVQES 103
            +WD+ GQ++   + R Y+++    I + D   +   Q +
Sbjct: 129 QLWDIAGQERFTSMTRVYYKDAHACIVMFDLTQKNTYQNA 10
>33380
          Length = 282

 Score = 30.8 bits (68), Expect = 0.30,   Method: Compositional matrix adjust.
 Identities = 16/74 (21%), Positives = 34/74 (45%)
 Frame = +3

Query: 59  KNICFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVQESADELQKMLQEDELRD 118
           K +   +WD  GQ++ R +   Y++   G I + D  + E      D   + ++     +
Sbjct: 54  KRVKLQIWDTAGQERYRTITTAYYRGAMGFILMYDVTNEESFNAVQDWCTQ-IKTYSWDN 230

Query: 119 AVLLVFANKQDMPN 132
           A +++  NK D+ +
Sbjct: 231 AQVVLVGNKCDLED 272
>26536
          Length = 829

 Score = 30.8 bits (68), Expect = 0.31,   Method: Compositional matrix adjust.
 Identities = 23/99 (23%), Positives = 44/99 (44%), Gaps = 7/99 (7%)
 Frame = +2

Query: 59  KNICFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVQESADELQ--KMLQEDEL 116
           + + +T  D  GQ++   +  HY ++  G I V    D    QE+    +     Q++  
Sbjct: 122 RRVSWTFLDTAGQEEYSSMREHYTRSGDGFIVVYSVTDVTSFQEAEAVFRWLTRFQDETS 301

Query: 117 RDAVLLVFANKQDMPNAMPVS-----ELTDKLGLQHLRS 150
             AVL    NK D+ +   V+     ++ D+LG+ +  +
Sbjct: 302 IHAVLC--GNKTDLTSDRKVTPEEGRKMADRLGMLYFET 412
>05468
          Length = 1558

 Score = 30.4 bits (67), Expect = 0.46,   Method: Compositional matrix adjust.
 Identities = 27/125 (21%), Positives = 58/125 (46%), Gaps = 14/125 (11%)
 Frame = -3

Query: 19   RILMVGLDAAGKTTIL-----------YKLKLGEIVTTIPTIGFNVETVEYKNICFTVWD 67
            +IL++G    GKT+I+           Y+  +G +   +  + ++ +T+    I   +WD
Sbjct: 1535 KILVIGELGTGKTSIIKRYVHQFFSQHYRATIG-VDFALKVLNWDADTL----IRLQLWD 1371

Query: 68   VGGQDKIRPLWRHYFQNTQGLIFVVD---SNDRERVQESADELQKMLQEDELRDAVLLVF 124
            + GQ++   + R Y++   G   V D   ++  + V +  ++L   +Q  +      ++ 
Sbjct: 1370 IAGQERFGNMTRVYYKEAVGAFVVFDVTRASTFDAVTKWKNDLDSKVQLADGSPVPCVLL 1191

Query: 125  ANKQD 129
            ANK D
Sbjct: 1190 ANKCD 1176
>08444
          Length = 715

 Score = 28.9 bits (63), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 20/69 (28%), Positives = 36/69 (52%)
 Frame = +1

Query: 69  GGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVQESADELQKMLQEDELRDAVLLVFANKQ 128
           G  DK+  LWR    NT+    +V    R+ ++E   ++Q+++  D  RD  LL+  +  
Sbjct: 217 GSSDKLLALWRSPVFNTETSQELV-GFQRQGLEELGRQMQEIMNFDPARD--LLLNPSNP 387

Query: 129 DMPNAMPVS 137
           D+P   P++
Sbjct: 388 DLPWGFPLA 414
>11257
          Length = 1102

 Score = 28.5 bits (62), Expect = 1.7,   Method: Compositional matrix adjust.
 Identities = 17/95 (17%), Positives = 46/95 (48%), Gaps = 10/95 (10%)
 Frame = -2

Query: 46   IPTIGFNVETVEYKNIC-----FT--VWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRE 98
            +P++  +   V +K++      FT  +WD  GQ++ + L   +++ T   +     ++ +
Sbjct: 1092 MPSLPHDRRGVPHKDVVVDGETFTMQIWDTAGQERYKSLRTPFYRGTDCCLLTFSVDNLK 913

Query: 99   RVQESADELQKMLQEDELRDAV---LLVFANKQDM 130
             +Q  +D   + +   +++D+     ++  NK D+
Sbjct: 912  SLQSLSDWYDEFVNYADIQDSASFPFVIIGNKADI 808
>29881
          Length = 416

 Score = 27.3 bits (59), Expect = 3.1,   Method: Compositional matrix adjust.
 Identities = 10/29 (34%), Positives = 15/29 (51%)
 Frame = -2

Query: 57  EYKNICFTVWDVGGQDKIRPLWRHYFQNT 85
           E + +CF+VW  G +  +   WRH    T
Sbjct: 403 EGRQLCFSVWCPG*RHHVEEGWRHVHSGT 317
>17511
          Length = 483

 Score = 26.6 bits (57), Expect = 5.8,   Method: Compositional matrix adjust.
 Identities = 23/121 (19%), Positives = 51/121 (42%), Gaps = 8/121 (6%)
 Frame = -3

Query: 18  MRILMVGLDAAGKTTILYKLKLGEIVTTI-PTIGFNVET----VEYKNICFTVWDVGGQD 72
           ++++++G    GKT+++ +    +       TIG +  T    V+ + +   +WD  GQ+
Sbjct: 364 LKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQIWDTAGQE 185

Query: 73  KIRPLWRHYFQNTQGLIFVVD---SNDRERVQESADELQKMLQEDELRDAVLLVFANKQD 129
           + + L   +++     + V D    N    +    DE        +  +   +V  NK D
Sbjct: 184 RFQSLGVAFYRGADCCVLVFDVTMPNTFRSLDSWRDEFLIQASPRDPENFPFVVIGNKID 5

Query: 130 M 130
           +
Sbjct: 4   L 2
>34359
          Length = 1042

 Score = 26.6 bits (57), Expect = 5.8,   Method: Compositional matrix adjust.
 Identities = 23/118 (19%), Positives = 49/118 (41%), Gaps = 4/118 (3%)
 Frame = +3

Query: 17  QMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKN----ICFTVWDVGGQD 72
             ++++VG        I+ +   G     + T+G  V  +++      + F VWD  GQ+
Sbjct: 51  NFKLVLVGGRWEWANNIVKRHVTGS*KKYVATLGVEVHPLQFNTSRGLLRFNVWDTAGQE 230

Query: 73  KIRPLWRHYFQNTQGLIFVVDSNDRERVQESADELQKMLQEDELRDAVLLVFANKQDM 130
           K   L   Y+      I + D   R   +   +  + +++  E  +  +++  NK D+
Sbjct: 231 KFGGLRDGYYIQGTCAIIMFDVTSRVTYKNVPNWHRDLVRVCE--NIPIVLCGNKVDI 398
>10691
          Length = 857

 Score = 26.6 bits (57), Expect = 6.0,   Method: Compositional matrix adjust.
 Identities = 11/34 (32%), Positives = 19/34 (55%)
 Frame = +2

Query: 59  KNICFTVWDVGGQDKIRPLWRHYFQNTQGLIFVV 92
           K+ C  +W V G+D    + ++  +N Q  IFV+
Sbjct: 104 KDFCLELW-VSGKDDFNKIRKYNIRNNQSAIFVI 202
>05400
          Length = 1916

 Score = 26.2 bits (56), Expect = 6.9,   Method: Compositional matrix adjust.
 Identities = 11/22 (50%), Positives = 13/22 (59%)
 Frame = -3

Query: 60   NICFTVWDVGGQDKIRPLWRHY 81
            N+CF VW   GQ     LWRH+
Sbjct: 1155 NVCFMVWTFFGQ-----LWRHF 1105
>01972
          Length = 2359

 Score = 25.8 bits (55), Expect = 9.3,   Method: Compositional matrix adjust.
 Identities = 12/35 (34%), Positives = 16/35 (45%)
 Frame = +3

Query: 63  FTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDR 97
           F VWD  GQ+K   L   Y+   Q  + + D   R
Sbjct: 453 FNVWDTAGQEKFGGLRDGYYIQGQCAVIMFDVTSR 557
>22540
          Length = 337

 Score = 25.8 bits (55), Expect = 9.3,   Method: Compositional matrix adjust.
 Identities = 10/14 (71%), Positives = 13/14 (92%)
 Frame = +2

Query: 166 LYDGLDWLSHELSK 179
           LY+GLDWLS+EL+ 
Sbjct: 2   LYEGLDWLSNELAS 43
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6756039|ref|NP_035869.1| tyrosine
3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta
polypeptide [Mus musculus]
         (245 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

12344                                                                 299   6e-82
13465                                                                 171   4e-43
33715                                                                 163   5e-41
15092                                                                 129   2e-30
17028                                                                 125   2e-29
27988                                                                  63   1e-10
05430                                                                  29   1.8  
03892                                                                  27   9.6  
05964                                                                  27   9.8  
>12344
          Length = 1658

 Score =  299 bits (766), Expect = 6e-82,   Method: Compositional matrix adjust.
 Identities = 146/228 (64%), Positives = 179/228 (78%)
 Frame = +2

Query: 2   EKTELIQKAKLAEQAERYDDMATCMKAVTEQGAELSNEERNLLSVAYKNVVGGRRSAWRV 61
           ++ + + +AK   +AERYD+M   MK V     EL+ EERNLLSVAYKNV+G RR++WR+
Sbjct: 62  DREDQVYQAKQLNRAERYDEMVKFMKIVACMDVELTVEERNLLSVAYKNVIGARRASWRI 241

Query: 62  ISSIEQKTDTSDKKLQLIKDYREKVESELRSICTTVLELLDKYLIANATNPESKVFYLKM 121
           +SS+EQK D  + K  + K+YR K+E EL+ IC  VL++L+K+LI NA   ESKVFY KM
Sbjct: 242 VSSLEQKEDKCEDKKAINKEYRMKIEKELKDICEDVLDILEKHLIVNANTGESKVFYYKM 421

Query: 122 KGDYFRYLAEVACGDDRKQTIENSQGAYQEAFDISKKEMQPTHPIRLGLALNFSVFYYEI 181
           KGDY RYLAE A G+DRK+  ENS  AY+ A DI+  E+ PTHPIRLGLALNFSVFYYEI
Sbjct: 422 KGDYHRYLAEFAVGNDRKEAAENSLVAYKAASDIAMIELAPTHPIRLGLALNFSVFYYEI 601

Query: 182 LNNPELACTLAKTAFDEAIAELDTLNEDSYKDSTLIMQLLRDNLTLWT 229
           LN+P+ AC LAK AFD+AIAELDTL+E+SYKDSTLIMQLLRDNLTLWT
Sbjct: 602 LNSPDRACRLAKAAFDDAIAELDTLSEESYKDSTLIMQLLRDNLTLWT 745
>13465
          Length = 596

 Score =  171 bits (432), Expect = 4e-43,   Method: Compositional matrix adjust.
 Identities = 83/151 (54%), Positives = 113/151 (74%), Gaps = 2/151 (1%)
 Frame = +2

Query: 2   EKTELIQKAKLAEQAERYDDMATCMKAVTEQGAELSNEERNLLSVAYKNVVGGRRSAWRV 61
           ++ + + +AKLAEQAERYD+M   MK V   G +L+ EERNLLSVAYKNV+G RR++WR+
Sbjct: 116 DRDDFVYQAKLAEQAERYDEMVEAMKKVASMGNDLTVEERNLLSVAYKNVIGARRASWRI 295

Query: 62  ISSIEQKT-DTSDK-KLQLIKDYREKVESELRSICTTVLELLDKYLIANATNPESKVFYL 119
           +SS+EQK  D  D  K ++ K YR+++E+EL+ IC  VL+++D +LI + T  ESKVFY 
Sbjct: 296 VSSVEQKDLDKPDPDKGKMTKGYRQQIETELKQICEDVLKIIDDHLIPSTTQGESKVFYY 475

Query: 120 KMKGDYFRYLAEVACGDDRKQTIENSQGAYQ 150
           KMKGDY+RYLAE A GD RK+  E+S  AY+
Sbjct: 476 KMKGDYYRYLAEFATGDPRKEAAESSLVAYK 568
>33715
          Length = 434

 Score =  163 bits (413), Expect = 5e-41,   Method: Compositional matrix adjust.
 Identities = 78/111 (70%), Positives = 92/111 (82%)
 Frame = -1

Query: 119 LKMKGDYFRYLAEVACGDDRKQTIENSQGAYQEAFDISKKEMQPTHPIRLGLALNFSVFY 178
           LKMKGDY+RYL+EV+ G+ RK+ +  S  AY+EA D++K+ +  THPIRLGLALNFSVF+
Sbjct: 374 LKMKGDYYRYLSEVSQGEQRKENVGKSMEAYKEATDMAKERLSSTHPIRLGLALNFSVFH 195

Query: 179 YEILNNPELACTLAKTAFDEAIAELDTLNEDSYKDSTLIMQLLRDNLTLWT 229
           YEI N P+ AC LAK AFDEAI  LD LNE+SYKDSTLIMQLLRDNLTLWT
Sbjct: 194 YEIKNCPDEACRLAKIAFDEAIQCLDQLNEESYKDSTLIMQLLRDNLTLWT 42
>15092
          Length = 692

 Score =  129 bits (323), Expect = 2e-30,   Method: Compositional matrix adjust.
 Identities = 67/110 (60%), Positives = 77/110 (70%), Gaps = 8/110 (7%)
 Frame = +3

Query: 3   KTELIQKAKLAEQAERYDDMATCMKAVTEQG--------AELSNEERNLLSVAYKNVVGG 54
           K   +  AK+AEQAERYDDMA  M     +G        + L NEERNLLSVAYKNVVG 
Sbjct: 231 KERQVHAAKIAEQAERYDDMAESMHKCVVEGYSANGDKSSTLDNEERNLLSVAYKNVVGA 410

Query: 55  RRSAWRVISSIEQKTDTSDKKLQLIKDYREKVESELRSICTTVLELLDKY 104
           RRSAWRVISSIEQKT+ +DKKL++ K YREKVE EL+ ICT VL  +  Y
Sbjct: 411 RRSAWRVISSIEQKTENNDKKLEMAKKYREKVEKELKEICTQVLVRIHHY 560
>17028
          Length = 1078

 Score =  125 bits (313), Expect = 2e-29,   Method: Compositional matrix adjust.
 Identities = 60/92 (65%), Positives = 73/92 (79%), Gaps = 1/92 (1%)
 Frame = +1

Query: 139 KQTIENSQGAYQEAFDISKKEMQPTHPIRLGLALNFSVFYYEILNNPELACTLAKTAFDE 198
           ++ +  +Q AY +A +++K+ M PTHP RLGLALN+SVFYYEILN+ + AC LAKTAFDE
Sbjct: 28  QEAVTKAQEAYNKAMEVAKQSMAPTHPNRLGLALNYSVFYYEILNSQDKACDLAKTAFDE 207

Query: 199 AIAELDTLNE-DSYKDSTLIMQLLRDNLTLWT 229
           AI E+D   E D  KDSTLIMQLLRDNLTLWT
Sbjct: 208 AIQEMDQCGERDDCKDSTLIMQLLRDNLTLWT 303
>27988
          Length = 448

 Score = 62.8 bits (151), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 32/58 (55%), Positives = 41/58 (70%)
 Frame = +3

Query: 43  LLSVAYKNVVGGRRSAWRVISSIEQKTDTSDKKLQLIKDYREKVESELRSICTTVLEL 100
           L SVAYKNVVG RRS+WRVI  IEQK +T  +K +  + +R+ VE EL + C  VL+L
Sbjct: 276 LFSVAYKNVVGARRSSWRVICMIEQKAETQPRK-EKARAFRKDVEKELDATCNEVLKL 446

 Score = 47.4 bits (111), Expect = 6e-06,   Method: Compositional matrix adjust.
 Identities = 27/53 (50%), Positives = 29/53 (54%)
 Frame = +2

Query: 2   EKTELIQKAKLAEQAERYDDMATCMKAVTEQGAELSNEERNLLSVAYKNVVGG 54
           E  +LI  AKLAEQAERYDDMA  MK VTE    L  E R       +   GG
Sbjct: 152 ESKDLISFAKLAEQAERYDDMAKAMKKVTENDKTLMQESRXSFLCGVQKRRGG 310
>05430
          Length = 1492

 Score = 28.9 bits (63), Expect = 1.8,   Method: Compositional matrix adjust.
 Identities = 17/64 (26%), Positives = 27/64 (42%)
 Frame = -1

Query: 114 SKVFYLKMKGDYFRYLAEVACGDDRKQTIENSQGAYQEAFDISKKEMQPTHPIRLGLALN 173
           S +FY+K   D+FRY+  + C               ++ F I    +Q +H +   L   
Sbjct: 472 SVLFYIK--SDFFRYVVYICCDKRSPHRDAGCIAGTKQPFHIELDSLQ*SHCLCRYLVAR 299

Query: 174 FSVF 177
           F VF
Sbjct: 298 FWVF 287
>03892
          Length = 1043

 Score = 26.6 bits (57), Expect = 9.6,   Method: Compositional matrix adjust.
 Identities = 28/91 (30%), Positives = 45/91 (49%), Gaps = 6/91 (6%)
 Frame = +1

Query: 5   ELIQKAKLAEQAERYDDMATCMKAVTEQGAELSNEERNLL---SVAYKNVVGG--RRSAW 59
           E +Q+++LAE+ E  DD+    K   ++G + S  +R+L    S   +   GG  RR   
Sbjct: 604 EHLQESRLAEREEDRDDICGRQKRRRQEGPQTSRGQRSLQGR*SSHEERHEGGKSRR*ER 783

Query: 60  RVISSIEQKTDT-SDKKLQLIKDYREKVESE 89
             +   E+  +T  D+K+Q  K  R   ESE
Sbjct: 784 EGVQEGEKVRETKKDRKVQETKKDRRAGESE 876
>05964
          Length = 604

 Score = 26.6 bits (57), Expect = 9.8,   Method: Compositional matrix adjust.
 Identities = 11/33 (33%), Positives = 17/33 (51%)
 Frame = -1

Query: 48  YKNVVGGRRSAWRVISSIEQKTDTSDKKLQLIK 80
           YK V G  RS W  +  ++ +    D+  +LIK
Sbjct: 316 YKQVSGDERSVWTYLKLVDFRRVVDDRSFKLIK 218
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|18699726|ref|NP_569053.1| vacuolar protein sorting 4a
[Mus musculus]
         (437 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

20270                                                                 244   7e-82
03022                                                                 142   2e-34
25671                                                                 119   9e-34
07243                                                                 140   1e-33
01642                                                                 135   2e-32
00810                                                                 134   6e-32
19129                                                                 131   7e-31
02582                                                                 130   1e-30
23766                                                                 129   2e-30
27976                                                                 121   5e-28
07247                                                                 108   3e-24
12235                                                                 103   1e-22
38672                                                                  68   2e-18
17843                                                                  69   3e-12
14413                                                                  55   6e-08
26408                                                                  50   2e-06
01279                                                                  47   1e-05
02194                                                                  41   9e-04
06766                                                                  41   0.001
25936                                                                  35   0.067
15498                                                                  35   0.076
14519                                                                  30   1.5  
06169                                                                  30   2.0  
16321                                                                  28   5.0  
>20270
          Length = 542

 Score =  244 bits (622), Expect(2) = 7e-82,   Method: Compositional matrix adjust.
 Identities = 114/128 (89%), Positives = 124/128 (96%)
 Frame = -3

Query: 159 PWRGILLFGPPGTGKSYLAKAVATEANNSTFFSVSSSDLMSKWLGESEKLVKNLFELARQ 218
           PWRGILL+GPPGTGKSYLAKAVATEANNSTFFSVSSSDL+SKWLGESEKLVK LF+LAR+
Sbjct: 384 PWRGILLYGPPGTGKSYLAKAVATEANNSTFFSVSSSDLVSKWLGESEKLVKTLFQLARE 205

Query: 219 HKPSIIFIDEVDSLCGSRNENESEAARRIKTEFLVQMQGVGNNNDGTLVLGATNIPWVLD 278
           ++PSIIFIDEVD+LCGSR+ENESE+ARRIKTEFLVQMQGVGN+N G LVLGATNIPW LD
Sbjct: 204 NQPSIIFIDEVDALCGSRSENESESARRIKTEFLVQMQGVGNDNTGVLVLGATNIPWTLD 25

Query: 279 SAIRRRFE 286
           SAIRRRFE
Sbjct: 24  SAIRRRFE 1

 Score = 78.6 bits (192), Expect(2) = 7e-82,   Method: Compositional matrix adjust.
 Identities = 34/40 (85%), Positives = 39/40 (97%)
 Frame = -1

Query: 118 VMEKPNIRWNDVAGLEGAKEALKEAVILPIKFPHLFTGKR 157
           V+EKPN+RW+DVAGL GAK+ALKEAVILP+KFPHLFTGKR
Sbjct: 506 VVEKPNVRWDDVAGLNGAKDALKEAVILPVKFPHLFTGKR 387
>03022
          Length = 2255

 Score =  142 bits (359), Expect = 2e-34,   Method: Compositional matrix adjust.
 Identities = 79/225 (35%), Positives = 129/225 (57%), Gaps = 5/225 (2%)
 Frame = +2

Query: 122  PNIRWNDVAGLEGAKEALKEAVILPIKFPHLFTGKRTPWR-GILLFGPPGTGKSYLAKAV 180
            P   W DV  L   +  LK++++  I  P + +    P   GI+L GPPG GK+ +AKA+
Sbjct: 1412 PTTTWEDVGALSNVRAQLKDSILCRIHDPEVSSAFGLPTNSGIILVGPPGCGKTLVAKAM 1591

Query: 181  ATEANNSTFFSVSSSDLMSKWLGESEKLVKNLFELARQHKPSIIFIDEVDSLCGSRNENE 240
            A EA    F  +   +L+ K++GESE+ ++  F+ A+   P +IF DE+D+LC +R  N+
Sbjct: 1592 ANEAG-LNFIYIKGPELLDKYVGESERNLREKFDKAQACAPCLIFFDEMDTLCSNRQNND 1768

Query: 241  -SEAARRIKTEFLVQMQGVGNNNDGTLVLGATNIPWVLDSAIRR--RFEKRIYIPLPEEA 297
             S   + +  + L  M G G  +    V+GATNI   +D A++R  RF+++I+I LP+  
Sbjct: 1769 GSNVGKSVTNQLLALMDGCGERSQ-VYVMGATNIIENVDPALQRPGRFDRKIFIGLPDTD 1945

Query: 298  ARAQMFR-LHLGSTPHNLTDANIHELARKTEGYSGADISIIVRDS 341
             R  + R L  G +   L   ++ +LA+ TEG+SGAD+  +V ++
Sbjct: 1946 GRLDILRALTKGGSQRKLESCDMQQLAQDTEGFSGADLKHLVNEA 2080

 Score = 45.8 bits (107), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 22/73 (30%), Positives = 43/73 (58%)
 Frame = +1

Query: 160 WRGILLFGPPGTGKSYLAKAVATEANNSTFFSVSSSDLMSKWLGESEKLVKNLFELARQH 219
            R  LL+GP G+GK +LA+ +A +           + L+S   G+SE+ V++LF+ A   
Sbjct: 637 CRRYLLYGPRGSGKRFLAECIAGQL-KLPLLKPKINTLISGVSGDSEQRVRDLFDQAVSQ 813

Query: 220 KPSIIFIDEVDSL 232
            P ++++++++ L
Sbjct: 814 APCVLYLEDIECL 852
>25671
          Length = 441

 Score =  119 bits (298), Expect(2) = 9e-34,   Method: Compositional matrix adjust.
 Identities = 63/110 (57%), Positives = 81/110 (73%), Gaps = 5/110 (4%)
 Frame = +2

Query: 171 TGKSYLAKAVATEANNSTFFSVSSSDLMSKWLGESEKLVKNLFELARQHKPSIIFIDEVD 230
           TGK+ LAKAVATE   +TFF+VS+S L +K+ GESEKLV+ LFE+A  + PS IFIDE+D
Sbjct: 2   TGKTMLAKAVATECG-TTFFNVSTSSLANKYRGESEKLVRLLFEMAHFYAPSTIFIDEID 178

Query: 231 SLCGSR-NENESEAARRIKTEFLVQMQGVGNNND----GTLVLGATNIPW 275
           S+C  R +++E EA+RR+K+E LVQM GVG  ND      +VL ATN P 
Sbjct: 179 SICSKRGSDSEHEASRRVKSELLVQMDGVGVTNDDPSKAVMVLAATNFPL 328

 Score = 42.7 bits (99), Expect(2) = 9e-34,   Method: Compositional matrix adjust.
 Identities = 18/34 (52%), Positives = 23/34 (67%)
 Frame = +3

Query: 274 PWVLDSAIRRRFEKRIYIPLPEEAARAQMFRLHL 307
           PW +D A+RRR EKRIYIPLP    R  +  ++L
Sbjct: 324 PWDIDEALRRRLEKRIYIPLPSAEGRRVLLEINL 425
>07243
          Length = 1112

 Score =  140 bits (352), Expect = 1e-33,   Method: Compositional matrix adjust.
 Identities = 85/250 (34%), Positives = 140/250 (56%), Gaps = 23/250 (9%)
 Frame = +1

Query: 123 NIRWNDVAGLEGAKEALKEAVILPIKFPHLFTG-KRTPWRGILLFGPPGTGKSYLAKAVA 181
           ++ ++ + GL      L+E + LP+  P LF     TP +G LL+GPPGTGK+ LA+AVA
Sbjct: 193 DVTYSAIGGLTEQIRELREVIELPLLNPELFLRVGITPPKGCLLYGPPGTGKTLLARAVA 372

Query: 182 TEANNSTFFSVSSSDLMSKWLGESEKLVKNLFELARQHKPSIIFIDEVDSLCGSRNENES 241
           ++ + + F  V SS ++ K++GES +L++ +F  AR H+P IIF+DE+D++ G R    +
Sbjct: 373 SQLD-ANFLKVVSSAIVDKYIGESARLIREMFNYARDHQPCIIFMDEIDAIGGRRFSEGT 549

Query: 242 EAARRIK---TEFLVQMQGVGNNNDGTLVLGATNIPWVLDSAIRR--RFEKRIYIPLPEE 296
            A R I+    E L QM G  +     +++ ATN P  LD A+ R  R +++I IPLP E
Sbjct: 550 SADREIQRTLMELLNQMDGFDSLGQVKMIM-ATNRPDTLDPALLRPGRLDRKIEIPLPNE 726

Query: 297 AARAQMFRLH-LGSTPHNLTDANIHELARKTEGYSGADI----------------SIIVR 339
            AR ++ ++H L    H   D     + + ++ ++GAD+                  +++
Sbjct: 727 QARLEILKIHALIIAKHGEID--YEAIVKLSDNFNGADLRNVCTEAGLFAIRAEREYVIQ 900

Query: 340 DSLMQPVRKV 349
           +  M+ VRKV
Sbjct: 901 EDFMKAVRKV 930
>01642
          Length = 1406

 Score =  135 bits (341), Expect = 2e-32,   Method: Compositional matrix adjust.
 Identities = 81/238 (34%), Positives = 139/238 (58%), Gaps = 7/238 (2%)
 Frame = -1

Query: 118  VMEKPNIRWNDVAGLEGAKEALKEAVILPIKFPHLFTGKRT-PWRGILLFGPPGTGKSYL 176
            +M  P   ++D+ G++  K+ ++EAV LP+    L+      P RG+L++GPPG GK+ L
Sbjct: 1022 LMRSPT*XYSDIGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTML 843

Query: 177  AKAVATEANNSTFFSVSSSDLMSKWLGESEKLVKNLFELARQHKPSIIFIDEVDSLCGSR 236
            AKAVA     + F  V  S+ + K+LGE  ++V+++F LA+++ P+IIFIDE+D++   R
Sbjct: 842  AKAVAHH-TTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKR 666

Query: 237  NENESEAAR---RIKTEFLVQMQGVGNNNDGTLVLGATNIPWVLDSAIRR--RFEKRIYI 291
             + ++ A R   RI  E L QM G     +  +++ ATN    LD A+ R  R +++I  
Sbjct: 665  FDAQTGADREVQRILLELLNQMDGFDQTVNVKVIM-ATNRADTLDPALLRPGRLDRKIEF 489

Query: 292  PLPEEAARAQMFRLHLGSTPHNLT-DANIHELARKTEGYSGADISIIVRDSLMQPVRK 348
            PLP+   +  +F    G    N++ + ++ +   + +  SGADI+ I +++ MQ VR+
Sbjct: 488  PLPDRRQKRLIFSTITGKM--NISEEVDLEDYVARPDKISGADINAICQEAGMQAVRE 321
>00810
          Length = 1431

 Score =  134 bits (338), Expect = 6e-32,   Method: Compositional matrix adjust.
 Identities = 86/211 (40%), Positives = 122/211 (57%), Gaps = 3/211 (1%)
 Frame = -3

Query: 132  LEGAKEALKEAVILPIKFPHLF--TGKRTPWRGILLFGPPGTGKSYLAKAVATEANNSTF 189
            LE   + +KE VILP K   LF  +    P +G+LL GPPG GK+ +AKA   +A  + F
Sbjct: 1429 LEDVIQDVKETVILPFKRADLFRHSSLLQPPKGVLLHGPPGCGKTMIAKA-TAKAAGARF 1253

Query: 190  FSVSSSDLMSKWLGESEKLVKNLFELARQHKPSIIFIDEVDSLCGSRNENESEAARRIKT 249
             ++  S L+ KW GES+K  + +F LA + +P+IIFIDE+DS   SR   + EA   IKT
Sbjct: 1252 INLQVSSLVDKWYGESQKRAEAVFSLAIKLQPTIIFIDEIDSFLRSRTSTDHEATAMIKT 1073

Query: 250  EFLVQMQGVGNNNDG-TLVLGATNIPWVLDSAIRRRFEKRIYIPLPEEAARAQMFRLHLG 308
            +F+    G+  + D   +V+GATN P  +D+AI RR     +I LP  A R  +F L L 
Sbjct: 1072 QFMSFWDGLMTDPDCRVMVMGATNRPQDVDAAILRRMPSMFHIGLPGPAQRRSIFNLIL- 896

Query: 309  STPHNLTDANIHELARKTEGYSGADISIIVR 339
             +   +   N  ELA  T+G+SG+DI  + R
Sbjct: 895  -SKERIDALNYDELAEMTDGFSGSDIREVCR 806
>19129
          Length = 1020

 Score =  131 bits (329), Expect = 7e-31,   Method: Compositional matrix adjust.
 Identities = 80/195 (41%), Positives = 119/195 (61%), Gaps = 8/195 (4%)
 Frame = +1

Query: 113 LMGAVVMEK-PNIRWNDVAGLEGAKEALKEAVILPIKFPHLF--TGKRTPWRGILLFGPP 169
           L+  +++EK P+  +  V GL+   + +KE + LP+K P LF   G   P +G+LL+GPP
Sbjct: 442 LVSLMMVEKVPDSTYEMVGGLDKQIKEIKEVIELPVKHPELFEALGIAQP-KGVLLYGPP 618

Query: 170 GTGKSYLAKAVATEANNSTFFSVSSSDLMSKWLGESEKLVKNLFELARQHKPSIIFIDEV 229
           GTGK+ LA+AVA      TF  VS S+L+ K++GE  ++V+ LF +AR+H PSIIF+DE+
Sbjct: 619 GTGKTLLARAVAHHTE-CTFIRVSGSELVQKFIGEGSRMVRELFVMAREHAPSIIFMDEI 795

Query: 230 DSLCGSRNENESEA---ARRIKTEFLVQMQGVGNNNDGTLVLGATNIPWVLDSAIRR--R 284
           DS+  SR E  S      +R   E L Q+ G     +  +++ ATN   +LDSA+ R  R
Sbjct: 796 DSIGSSRLEGGSGGDSEVQRTMLELLNQLDGFEPKQNIKVIM-ATNRIDILDSALLRPGR 972

Query: 285 FEKRIYIPLPEEAAR 299
            +++I  P P E AR
Sbjct: 973 IDRKIEFPPPNEEAR 1017
>02582
          Length = 1101

 Score =  130 bits (326), Expect = 1e-30,   Method: Compositional matrix adjust.
 Identities = 86/272 (31%), Positives = 145/272 (53%), Gaps = 36/272 (13%)
 Frame = +3

Query: 117 VVMEKPNIRWNDVAGLEGAKEALKEAVILPIKFPHLFTGKRTPW-RGILLFGPPGTGKSY 175
            +++  ++ W D+ GL+  K  +++AV  P+ +P  F     P  +G+LL+GPPG GK+ 
Sbjct: 111 CIVDARSVPWTDIGGLDLVKLQIRQAVEWPLLYPDTFQALGLPLTKGVLLYGPPGCGKTT 290

Query: 176 LAKAVATEANNSTFFSVSSSDLMSKWLGESEKLVKNLFELARQHKPSIIFIDEVDSLCGS 235
           LA+A AT  +  TF S+S + L S ++G++EK +   F+ AR   PSI+F+DE+D++ G 
Sbjct: 291 LAQAAATACH-VTFLSLSCAQLYSPYVGDAEKKISETFQKARALAPSILFLDEMDAIVGK 467

Query: 236 RNENE--SEAARRIKTEFLVQMQGVG---------------NNNDGT------------- 265
           R+++   S  + R+ +  L +M G+G                ++D T             
Sbjct: 468 RSDSSLGSGVSERVLSALLNEMDGIGVRLDDKSDSREMEIEGSSDHTPQVRQHAVKEAHD 647

Query: 266 ---LVLGATNIPWVLDSAIRR--RFEKRIYIPLPEEAARAQMFRLHLGSTPHNLTDANIH 320
              LV+ ATN P +LD A+ R  R ++ IY+P P+   R Q F +H    P    D ++ 
Sbjct: 648 RHVLVVAATNRPDMLDPALLRPGRMDRLIYVPPPDVQGRLQSFTIHTRKMPLG-KDVDVK 824

Query: 321 ELARKTEGYSGADISIIVRDSLMQPVRKVQSA 352
           +LA  T GY+GADI  +  +  +  +++  SA
Sbjct: 825 QLADLTAGYTGADIKTLCNEVGLLALKESMSA 920
>23766
          Length = 1463

 Score =  129 bits (324), Expect = 2e-30,   Method: Compositional matrix adjust.
 Identities = 76/199 (38%), Positives = 119/199 (59%), Gaps = 5/199 (2%)
 Frame = +1

Query: 155 GKRTPWRGILLFGPPGTGKSYLAKAVATEANNSTFFSVSSSDLMSKWLGESEKLVKNLFE 214
           G + P +G++L+GPPGTGK+ LAKAVA +  ++TF  V  S+L+ K+LG+  KLV+ LF 
Sbjct: 142 GNQAP-KGVILYGPPGTGKTLLAKAVANQ-TSATFLRVVGSELIQKYLGDGPKLVRELFR 315

Query: 215 LARQHKPSIIFIDEVDSLCGSRNENESEAARRIK---TEFLVQMQGVGNNNDGTLVLGAT 271
           +A +H PSI+FIDE+D++   R E+ S   R I+    E L Q+ G  +  D  +++ AT
Sbjct: 316 VAEEHAPSIVFIDEIDAVGTKRYESNSGGEREIQRTMLELLNQLDGFDSRGDVKVIM-AT 492

Query: 272 NIPWVLDSAIRR--RFEKRIYIPLPEEAARAQMFRLHLGSTPHNLTDANIHELARKTEGY 329
           N    LD A+ R  R +++I  PLP+E  + ++F +H  S      D NI +     +  
Sbjct: 493 NRIETLDPALIRPGRIDRKIEFPLPDEKTKRRIFTIHT-SRMTLAGDVNIDDYVMSKDDL 669

Query: 330 SGADISIIVRDSLMQPVRK 348
           SGADI  I  ++ +  +R+
Sbjct: 670 SGADIKAICTEAGLLALRE 726
>27976
          Length = 421

 Score =  121 bits (304), Expect = 5e-28,   Method: Compositional matrix adjust.
 Identities = 57/67 (85%), Positives = 64/67 (95%)
 Frame = +3

Query: 2   TTSTLQKAIDLVTKATEEDKAKNYEEALRLYQHAVEYFLHAIKYEAHSDKAKESIRAKCM 61
            ++TLQKAIDLVTKATEEDK KN+EEALRLY+H+VEYFLHAIKYEA S+KAK+SIRAKCM
Sbjct: 105 NSNTLQKAIDLVTKATEEDKNKNFEEALRLYEHSVEYFLHAIKYEASSEKAKDSIRAKCM 284

Query: 62  QYLDRAE 68
           QYLDRAE
Sbjct: 285 QYLDRAE 305
>07247
          Length = 1753

 Score =  108 bits (271), Expect = 3e-24,   Method: Compositional matrix adjust.
 Identities = 63/184 (34%), Positives = 107/184 (58%), Gaps = 5/184 (2%)
 Frame = -2

Query: 169  PGTGKSYLAKAVATEANNSTFFSVSSSDLMSKWLGESEKLVKNLFELARQHKPSIIFIDE 228
            PGTGK+ LA+AVA++ +   F  V SS ++ K++GES +L++ +F  AR H+P IIF+DE
Sbjct: 1407 PGTGKTLLARAVASQLD-CNFLKVVSSAIVDKYIGESARLIREMFAFARDHEPCIIFMDE 1231

Query: 229  VDSLCGSRNENESEAARRIK---TEFLVQMQGVGNNNDGTLVLGATNIPWVLDSAIRR-- 283
            +D++ G R    + A R I+    E L QM G        +++ ATN P  LD A+ R  
Sbjct: 1230 IDAIGGRRFSEGTSADREIQRTLMELLNQMDGFDALGQVKMIM-ATNRPDTLDPALLRPG 1054

Query: 284  RFEKRIYIPLPEEAARAQMFRLHLGSTPHNLTDANIHELARKTEGYSGADISIIVRDSLM 343
            R +++I I LP E AR ++ ++H      +  + +   + + +E ++GAD+  +  ++ M
Sbjct: 1053 RLDRKIEISLPNEQARLEILKIHANPIAKH-GEIDWEAVVKLSEDFNGADLRNVCTEAGM 877

Query: 344  QPVR 347
              +R
Sbjct: 876  FAIR 865
>12235
          Length = 1749

 Score =  103 bits (258), Expect = 1e-22,   Method: Compositional matrix adjust.
 Identities = 61/184 (33%), Positives = 105/184 (57%), Gaps = 12/184 (6%)
 Frame = +1

Query: 186 NSTFFSVSSSDLMSKWLGESEKLVKNLFELARQHKPSIIFIDEVDSLC---GSRNENESE 242
           N  F +VS S+ +  ++G     V+++F  AR++ P I+F+DE+D++      RN     
Sbjct: 7   NVPFITVSGSEFLEMFVGVGPSRVRDMFATARKNAPCILFVDEIDAVGRKRSGRNFGGQS 186

Query: 243 AARRIKTEFLVQMQGVGNNNDGTLVLGATNIPWVLDSAIRR--RFEKRIYIPLPEEAARA 300
                  + LV+M G  N   G +VL ATN   +LD+A+ R  RF+++I++PLP+   RA
Sbjct: 187 EQENTLNQLLVEMDGF-NTQTGVVVLAATNRVDILDAALLRPGRFDRQIFVPLPDIKXRA 363

Query: 301 QMFRLHLGSTPHNLTDANIHELARK----TEGYSGADISIIVRDSLMQPVRKVQSA---T 353
            +F++HL       T+ N ++LARK    T G+SGADI+ +  ++ +   R + ++   T
Sbjct: 364 SIFKVHLDPLK---TEVNKNDLARKMAALTPGFSGADIANVCNEAALIAARDLNTSIHMT 534

Query: 354 HFKK 357
           HF++
Sbjct: 535 HFEQ 546
>38672
          Length = 730

 Score = 67.8 bits (164), Expect(2) = 2e-18,   Method: Compositional matrix adjust.
 Identities = 41/160 (25%), Positives = 82/160 (51%), Gaps = 4/160 (2%)
 Frame = -3

Query: 238 ENESEAARRIKTEFLVQMQGVGNNNDGTLVLGATNIPWVLDSAIRR--RFEKRIYIPLPE 295
           E   E  RRI ++ L  M G+   +   +V+ ATN P  +D+A+RR  RF++ + I +P+
Sbjct: 608 ETHGEVERRIVSQLLTLMDGLKQRSH-VIVMAATNRPNSVDAALRRFGRFDREVDIGIPD 432

Query: 296 EAARAQMFRLHLGSTPHNLTDANIHELARKTEGYSGADISIIVRDSLMQPVRKVQSATHF 355
              R ++ R+H  +      D ++ ++A +T G+ GAD++ +  ++ +Q +R+       
Sbjct: 431 ATGRLEILRIHTKNMKLA-DDVDLEQVASETHGHVGADVAALCSEAALQQIREKMDLIDL 255

Query: 356 KK--VCGPSRTNPSVMIDDLLTPCSPGDPGAIEMTWMDVP 393
           +   +      + +V +DD        +P A+  T ++VP
Sbjct: 254 EDDTIDAEVLDSLAVTMDDFRWALGKSNPSALRETCVEVP 135

 Score = 42.4 bits (98), Expect(2) = 2e-18,   Method: Compositional matrix adjust.
 Identities = 19/40 (47%), Positives = 28/40 (70%)
 Frame = -1

Query: 197 LMSKWLGESEKLVKNLFELARQHKPSIIFIDEVDSLCGSR 236
           +MSK  GESE  ++  FE A ++ P+IIFIDE+D++   R
Sbjct: 730 IMSKLAGESESNLRKAFEEAEKNAPAIIFIDELDAIAPKR 611

 Score = 42.4 bits (98), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 20/48 (41%), Positives = 28/48 (58%), Gaps = 1/48 (2%)
 Frame = -3

Query: 119 MEKPNIRWNDVAGLEGAKEALKEAVILPIKFPHLFTG-KRTPWRGILL 165
           +E PN+ W DV GLE  K+ L+E V  P++ P  F     TP +G+L 
Sbjct: 146 VEVPNVSWEDVGGLENVKKELQELVQYPVEHPEKFLKFGMTPSKGVLF 3
>17843
          Length = 772

 Score = 69.3 bits (168), Expect = 3e-12,   Method: Compositional matrix adjust.
 Identities = 60/200 (30%), Positives = 90/200 (45%), Gaps = 21/200 (10%)
 Frame = +1

Query: 125 RWNDVAGLEGAKEALKEAVILPIKFP--HLFTGKRTPWRGILLFGPPGTGKSYLAKAVAT 182
            W+ +   E  KE L       + F   H+ +   +  R ILL GPPGTGK+ L KA+A 
Sbjct: 73  HWDSLVFDENIKERLLNYATTTLLFSDKHVNSSIISWNRVILLHGPPGTGKTTLCKALAH 252

Query: 183 EA--------NNSTFFSVSSSDLMSKWLGESEKLVKNLFELARQHKPSI-------IFID 227
           +         +      ++S  L SKW  ES KLV  +F+  R H   +       + ID
Sbjct: 253 KLCIRLSHRFSCGQLVEINSHSLFSKWFSESGKLVTKMFQ--RLHDYMVDPELLVCVLID 426

Query: 228 EVDSLCGSR----NENESEAARRIKTEFLVQMQGVGNNNDGTLVLGATNIPWVLDSAIRR 283
           EV+SL  +R    N NE   A R+    L Q+  +    +  L+L  +NI   +D A   
Sbjct: 427 EVESLTAARKSCLNGNEPSDAIRVVNAVLTQIDQLKKFAN-CLILTTSNITGAIDLAFVD 603

Query: 284 RFEKRIYIPLPEEAARAQMF 303
           R + + YI  P   A  +++
Sbjct: 604 RADIKQYIGPPTPPAIYKIY 663
>14413
          Length = 826

 Score = 55.1 bits (131), Expect = 6e-08,   Method: Compositional matrix adjust.
 Identities = 44/141 (31%), Positives = 70/141 (49%), Gaps = 12/141 (8%)
 Frame = +2

Query: 176 LAKAVATEANNSTFFS----VSSSDLMSKWLGESEKLVKNLF----ELAR-QHKPSIIFI 226
           LA+ +A    NS  ++    ++S  L SKW  ES KLV  LF    ELA  ++    + I
Sbjct: 23  LAEKLAIRTQNSFAYTHLVEINSHSLFSKWFSESGKLVARLFGKIGELATDKNNLVCVLI 202

Query: 227 DEVDSLCGSR---NENESEAARRIKTEFLVQMQGVGNNNDGTLVLGATNIPWVLDSAIRR 283
           DEV+SL  +R   + NE   A R+    L Q+  +       L+L  +N+   +D A   
Sbjct: 203 DEVESLAYARSAMSSNEPRDAMRVVNAVLTQLDEI-KACPNVLILATSNLAQSIDLAFLD 379

Query: 284 RFEKRIYIPLPEEAARAQMFR 304
           R + R +I LP+  A + +++
Sbjct: 380 RADIRQFIGLPDPLAISSIYK 442
>26408
          Length = 463

 Score = 49.7 bits (117), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 26/49 (53%), Positives = 35/49 (71%), Gaps = 2/49 (4%)
 Frame = +1

Query: 135 AKEALKEAVILPIKFPHLF--TGKRTPWRGILLFGPPGTGKSYLAKAVA 181
           A + +KE + LP+K P LF   G   P +G+LL+GPPGTGK+ LA+AVA
Sbjct: 286 ANQRIKEVIELPVKHPELFDALGIAQP-KGVLLYGPPGTGKTLLARAVA 429
>01279
          Length = 2183

 Score = 47.0 bits (110), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 30/85 (35%), Positives = 45/85 (52%), Gaps = 1/85 (1%)
 Frame = -3

Query: 129  VAGLEGAKEALKEAVILPIKFPHLFTGKRTPWRGILLFGPPGTGKSYLAKAVATEANNST 188
            + G EGA+EA    V        L   K+   R +LL GPPGTGK+ +A A+A E  N  
Sbjct: 1989 LVGQEGAREAAGVVV-------ELIKTKKMAGRAVLLAGPPGTGKTAIALAIAQELGNKV 1831

Query: 189  -FFSVSSSDLMSKWLGESEKLVKNL 212
             F  +  S++ S  + ++E L++N 
Sbjct: 1830 PFCPMVGSEVYSSEIKKTEVLMENF 1756
>02194
          Length = 1891

 Score = 41.2 bits (95), Expect = 9e-04,   Method: Compositional matrix adjust.
 Identities = 40/141 (28%), Positives = 68/141 (48%), Gaps = 7/141 (4%)
 Frame = -1

Query: 150  PHLFTGKRTPWR-GILLFGPPGTGKSYLAKAVATEANNSTFFSVSSSDLMSKWLGESEKL 208
            P  +  +  P+R G LL+GPPG GKS    A+A   +    +++   +L  K  G S+  
Sbjct: 1531 PRWYMDRGIPYRRGYLLYGPPGCGKSSYIMALAGALD----YNICVLNLSEK--GLSDDR 1370

Query: 209  VKNLFELARQHKPSIIFIDEVDSLCGSRNENESEAA------RRIKTEFLVQMQGVGNNN 262
            + +L  +A +   SII +++VD+   SR+ ++   A      R   +  L  + GV  + 
Sbjct: 1369 LNHLLTVAPEQ--SIILLEDVDAAFLSRDLSKENPAMYQGMGRLTFSGLLNALDGVA-SA 1199

Query: 263  DGTLVLGATNIPWVLDSAIRR 283
            +  +V   TN    LD A+ R
Sbjct: 1198 EARIVFMTTNYLDRLDPALIR 1136
>06766
          Length = 976

 Score = 41.2 bits (95), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 20/69 (28%), Positives = 42/69 (60%)
 Frame = +2

Query: 284 RFEKRIYIPLPEEAARAQMFRLHLGSTPHNLTDANIHELARKTEGYSGADISIIVRDSLM 343
           R ++ IYIPLP++ +R  + + +L  +P    + ++  +A+ T+G+SGAD++ I + +  
Sbjct: 2   RLDQLIYIPLPDDKSREAILKANLRKSPL-AKEVDLTYIAKVTQGFSGADLTEICQRACK 178

Query: 344 QPVRKVQSA 352
             +R+   A
Sbjct: 179 LAIRQAIEA 205
>25936
          Length = 459

 Score = 35.0 bits (79), Expect = 0.067,   Method: Compositional matrix adjust.
 Identities = 14/28 (50%), Positives = 18/28 (64%)
 Frame = +2

Query: 126 WNDVAGLEGAKEALKEAVILPIKFPHLF 153
           W+DV GLEG K +L E +  P K+P L 
Sbjct: 338 WSDVGGLEGVKSSLIETLQWPSKYPELL 421
>15498
          Length = 769

 Score = 34.7 bits (78), Expect = 0.076,   Method: Compositional matrix adjust.
 Identities = 26/89 (29%), Positives = 46/89 (51%), Gaps = 3/89 (3%)
 Frame = -1

Query: 132 LEGAKEALKEAVILPIKFPHLFTGKRTPW-RGILLFGPPGTGKSYLAKAVATEANNSTFF 190
           L   +  + E  ILP+  P +   ++ P  + ILL GP G+GK  L  A+  E   +  F
Sbjct: 268 LSDVRRLVTEFGILPLGSPSVH--EQAPLTKSILLAGPRGSGKKMLVHALCNEV-GANLF 98

Query: 191 SVSSSDLMSKWLGES--EKLVKNLFELAR 217
            +S ++L  K+ G+   + L+  +F++ R
Sbjct: 97  DLSPANLAGKYPGKDGLKMLMHLIFKVGR 11
>14519
          Length = 945

 Score = 30.4 bits (67), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 35/121 (28%), Positives = 58/121 (47%), Gaps = 1/121 (0%)
 Frame = -3

Query: 107 KKLQEQLMGAVVMEKPNIRWNDVAGLEGAKEALKEAVILPIKFPHLFTGKRTPWRGILLF 166
           ++L+E+L+  +     +IR    AG++      K+A+I  +K   +    RTP    LL 
Sbjct: 754 EQLEERLLFFLQQYNESIRG---AGMDLV--FFKDAMIHLLKISRII---RTPRGHALLV 599

Query: 167 GPPGTGKSYLAKAVATEANNSTF-FSVSSSDLMSKWLGESEKLVKNLFELARQHKPSIIF 225
           G  G+GK  L +  +  A   TF  +++ S  +S  L +    +KNL+  A Q    I F
Sbjct: 598 GVGGSGKQSLTRLSSFIAGYKTFQITLTRSYNVSNLLDD----LKNLYRTAGQEGKGITF 431

Query: 226 I 226
           I
Sbjct: 430 I 428
>06169
          Length = 1084

 Score = 30.0 bits (66), Expect = 2.0,   Method: Compositional matrix adjust.
 Identities = 14/44 (31%), Positives = 22/44 (50%)
 Frame = -1

Query: 163 ILLFGPPGTGKSYLAKAVATEANNSTFFSVSSSDLMSKWLGESE 206
           + +FG  G G   L K     AN +  F+++  D ++ W G SE
Sbjct: 634 VFMFGAAGVGTVALHKIFLKGANPALDFAMAGLDYLTYWAGASE 503
>16321
          Length = 870

 Score = 28.5 bits (62), Expect = 5.0,   Method: Compositional matrix adjust.
 Identities = 21/52 (40%), Positives = 24/52 (46%), Gaps = 3/52 (5%)
 Frame = -1

Query: 192 VSSSDLMSKWL---GESEKLVKNLFELARQHKPSIIFIDEVDSLCGSRNENE 240
           VS S     WL   G    LV+   ELA+  K  IIF   +  L G R ENE
Sbjct: 618 VSRSVFPKHWLHIIGSGNPLVR---ELAKISKSKIIFKKNISKLKGDRQENE 472
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|156255171|ref|NP_001019629.2| adducin 1 (alpha)
isoform 1 [Mus musculus]
         (735 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

08503                                                                 270   1e-81
12858                                                                 216   3e-56
06772                                                                  50   3e-06
23628                                                                  34   0.21 
>08503
          Length = 985

 Score =  270 bits (689), Expect(3) = 1e-81,   Method: Compositional matrix adjust.
 Identities = 127/240 (52%), Positives = 176/240 (73%), Gaps = 4/240 (1%)
 Frame = +3

Query: 124 VTPVNDLRGSDSIAYDKGEKLLRCKLAAFYRLADLFGWSQLIYNHITTRVNSEQEHFLIV 183
           V PVND+RG ++  Y K EK+LRCKLAA YRL DLF W+  I++HI+ RV+ EQE FL+ 
Sbjct: 138 VIPVNDIRGVETFGYSKQEKVLRCKLAACYRLIDLFXWTNGIHDHISMRVSQEQEQFLVN 317

Query: 184 PFGLLYSEVTASSLVKVNLQGDIVDRGSTNLGVNQAGFTLHSAVYAARPDAKCIVHIHTP 243
           P G+LYSE+TAS+L KV+++G++VD GST LG+++AGFTLHSA++ ARPD +CI+H+HT 
Sbjct: 318 PHGMLYSEMTASTLAKVDVRGEVVDTGSTGLGISKAGFTLHSALHQARPDLRCIIHLHTA 497

Query: 244 AGAAVSAMKCGLLPISPEALSLGDVAYHDYHGILVDEEEKILIQKNLGPKSKVLILRNHG 303
              AVSA KCGLLPIS EA+  G ++YHDY G L D+E++  + + LGP +KV+ LRNHG
Sbjct: 498 NVVAVSATKCGLLPISQEAMICGKISYHDYPGPLTDQEDRDQLGRCLGPFNKVMFLRNHG 677

Query: 304 LVSVGESVEEAFYYIHNLVVACEIQVRTLASAGGPDNLVLLD----PGKYKAKSRSPGTP 359
           ++  GE++EEAF+Y  N++ A E QV+ +    G DNL+L+D       +K  S+  G P
Sbjct: 678 VLVCGETIEEAFHYAFNVMAAVETQVKVMVV--GLDNLILVDEETQERTFKVGSQGEGAP 851

 Score = 50.4 bits (119), Expect(3) = 1e-81,   Method: Compositional matrix adjust.
 Identities = 21/40 (52%), Positives = 29/40 (72%)
 Frame = +2

Query: 366 SPPKWQIGEQEFEALMRMLDNLGYRTGYPYRYPALRERSK 405
           S  +W+ GE E+EALMR LDN GYRTG+ Y+ P +++  K
Sbjct: 857 SSRRWRCGELEWEALMRTLDNSGYRTGHLYKQPLMKQEKK 976

 Score = 24.3 bits (51), Expect(3) = 1e-81,   Method: Compositional matrix adjust.
 Identities = 8/17 (47%), Positives = 14/17 (82%)
 Frame = +2

Query: 69 EELESMIQEQFKKGKNP 85
          +ELE+++QEQ + G+ P
Sbjct: 2  DELEAVVQEQIRPGRAP 52
>12858
          Length = 851

 Score =  216 bits (550), Expect = 3e-56,   Method: Compositional matrix adjust.
 Identities = 106/195 (54%), Positives = 143/195 (73%), Gaps = 2/195 (1%)
 Frame = +1

Query: 220 GFTLHSAVYAARPDAKCIVHIHTPAGAAVSAMKCGLLPISPEALSLGDVAYHDYHGILVD 279
           GFTLHSA++ ARPD +CI+H+HTPA  AVSA K GLLP+S +AL  G V+YHDY+GILVD
Sbjct: 1   GFTLHSAIHQARPDIRCIIHLHTPAAVAVSATKQGLLPVSHQALMCGKVSYHDYNGILVD 180

Query: 280 EEEKILIQKNLGPKSKVLILRNHGLVSVGESVEEAFYYIHNLVVACEIQVRTLASAGGPD 339
           +EE+  + +NLGP +KV+ LRNHG+V+ GES+EEAF++  N++ AC++Q++ +    G D
Sbjct: 181 QEERDQLARNLGPFNKVMFLRNHGVVTCGESIEEAFHFAFNVMAACDVQMKVMPV--GID 354

Query: 340 NLVLLDPGKYKAKSRSPGTPAGEGSGSPPKWQIGEQEFEALMRMLDNLGYRTGYPYRYPA 399
           NLVLLD  + + K+   G   G  S S  KW+ GE EFEALMR LDN GYRTG+ Y+ P 
Sbjct: 355 NLVLLDE-ETQEKTYKAGRQTGTDS-SGRKWRCGELEFEALMRTLDNSGYRTGHVYKQPL 528

Query: 400 LRE--RSKKYSDVEV 412
           +++  + K  SDVEV
Sbjct: 529 MKQEKKEKMNSDVEV 573
>06772
          Length = 996

 Score = 50.1 bits (118), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 28/93 (30%), Positives = 50/93 (53%), Gaps = 9/93 (9%)
 Frame = +2

Query: 486 PNLFVPLNTNPKEVQEMRNKIREQNLQDIKTAGPQSQVLCGVMMDRSLVQGE-------L 538
           PN F P  +NPKE ++ +  I++   ++  +AGP S++L G+  D +    E       +
Sbjct: 191 PNQFAPQGSNPKEFRDKQKSIKKDYYEERVSAGPTSKILDGISWDEAAKMKEGGDQTVVV 370

Query: 539 VTASKAIIEKEYQPHVIV--STTGPNPFNTLTD 569
             ASK II++++Q + +V  S    NPF  + +
Sbjct: 371 GAASKGIIQRDHQHNAVVFRSYYAANPFENIAE 469
>23628
          Length = 1270

 Score = 33.9 bits (76), Expect = 0.21,   Method: Compositional matrix adjust.
 Identities = 19/59 (32%), Positives = 34/59 (57%), Gaps = 1/59 (1%)
 Frame = -3

Query: 495 NPKEVQEMRNKIREQNLQ-DIKTAGPQSQVLCGVMMDRSLVQGELVTASKAIIEKEYQP 552
            P  VQ MR+ + +Q++   +  A P + V C V + +SLV  +LV  ++A+I++   P
Sbjct: 461 TPTAVQRMRDSLTQQHVWFSLIQATPHNSVFCSVYLKKSLVCKQLV--NEALIKEGLAP 291
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|45592930|ref|NP_032940.1| protein phosphatase 3,
catalytic subunit, beta isoform [Mus musculus]
         (525 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

17953                                                                 214   2e-81
08242                                                                 221   7e-58
01173                                                                 220   9e-58
06264                                                                 219   2e-57
06084                                                                 184   9e-47
19040                                                                 155   5e-38
25536                                                                 120   2e-27
18336                                                                 102   9e-26
36367                                                                  65   5e-11
04295                                                                  45   7e-05
21146                                                                  40   0.003
30980                                                                  33   0.22 
>17953
          Length = 626

 Score =  214 bits (545), Expect(2) = 2e-81,   Method: Compositional matrix adjust.
 Identities = 112/178 (62%), Positives = 128/178 (71%)
 Frame = -3

Query: 340 IRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVTEMLVNVLSICSDDELMTEGEDQFDVGSA 399
           I +FNCSPHPYWLPNFMDVFTWSLPFVGEKVTEMLVN+L+ICSDDEL+TEG+D       
Sbjct: 483 IIKFNCSPHPYWLPNFMDVFTWSLPFVGEKVTEMLVNILNICSDDELVTEGDDS--AAEV 310

Query: 400 AARKEIIRNKIRAIGKMARVFSVLREESESVLTLKGLTPTGMLPSGVLAGGRQTLQSATV 459
           AARKE+IRNKIRAIGKMARVF+VLREESESVL LKGLTP G+LP G L+GG+ TL S   
Sbjct: 309 AARKEVIRNKIRAIGKMARVFTVLREESESVLQLKGLTPNGLLPLGALSGGKDTLTS--- 139

Query: 460 EAIEAEKAIRGFSPPHRICSFEEAKGLDRINERMPPRKDAVQQDGFNSLNTAHTTENH 517
                  A+ GFSP H+I  FEE        ++MP  K         +L T  TT+NH
Sbjct: 138 -------ALSGFSPSHKISGFEE--------DKMPGTK*MNVCLLAKTL*TIRTTKNH 10

 Score =  107 bits (266), Expect(2) = 2e-81,   Method: Compositional matrix adjust.
 Identities = 50/54 (92%), Positives = 51/54 (94%)
 Frame = -2

Query: 278 LQNNNLLSIIRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKAAVL 331
           LQ NNLLSIIRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNK  +L
Sbjct: 625 LQQNNLLSIIRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKVQLL 464
>08242
          Length = 3368

 Score =  221 bits (562), Expect = 7e-58,   Method: Compositional matrix adjust.
 Identities = 115/259 (44%), Positives = 159/259 (61%), Gaps = 1/259 (0%)
 Frame = -1

Query: 80   ILRREKTMIEVEAPITVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYFSIECV 139
            IL  E  +  V++P+TVCGDIHGQF+DL +LF+VGG   +T YLF+GD+VDRG++S+E  
Sbjct: 3365 ILVEESNVQRVDSPVTVCGDIHGQFYDLKELFKVGGDVPDTNYLFMGDFVDRGFYSVETF 3186

Query: 140  LYLWVLKILYPSTLFLLRGNHECRHLTEYFTFKQECKIKY-SERVYEACMEAFDSLPLAA 198
            L L  LK+ YP  + L+RGNHE R +T+ + F  EC  KY S  V+  C E FD L L+A
Sbjct: 3185 LLLLALKVRYPDRITLIRGNHESRQITQVYGFYDECLRKYGSITVWRYCTEIFDYLSLSA 3006

Query: 199  LLNQQFLCVHGGLSPEIHTLDDIRRLDRFKEPPAFGPMCDLLWSDPSEDFGNEKSQEHFS 258
            +++ +  CVHGGLSP I TLD IR +DR +E P  GPMCDLLWSDP +  G   S     
Sbjct: 3005 IIDGKIFCVHGGLSPSIQTLDQIRSIDRKQEVPHDGPMCDLLWSDPEDMQGWGVSP---- 2838

Query: 259  HNTVRGCSYFYNYPAVCEFLQNNNLLSIIRAHEAQDAGYRMYRKSQTTGFPSLITIFSAP 318
                RG  Y +    V +F   N +  I RAH+    GY+ +         +++T++SAP
Sbjct: 2837 ----RGAGYLFGSDVVSQFNAANXIDLICRAHQLVMEGYKWHFNE------TVLTVWSAP 2688

Query: 319  NYLDVYNNKAAVLKYENNV 337
            NY     N AA+L+ + ++
Sbjct: 2687 NYCYRCGNVAAILELDEHL 2631
>01173
          Length = 2619

 Score =  220 bits (561), Expect = 9e-58,   Method: Compositional matrix adjust.
 Identities = 106/259 (40%), Positives = 161/259 (62%)
 Frame = -1

Query: 80   ILRREKTMIEVEAPITVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYFSIECV 139
            I   +  ++E+EAP+ +CGDIHGQ++DL++LFE GG P  + YLFLGDYVDRG  S+E +
Sbjct: 2562 IFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETI 2383

Query: 140  LYLWVLKILYPSTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYEACMEAFDSLPLAAL 199
              L   KI YP   FLLRGNHEC  +   + F  ECK +Y+ ++++   + F+ LP+AA+
Sbjct: 2382 CLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAI 2203

Query: 200  LNQQFLCVHGGLSPEIHTLDDIRRLDRFKEPPAFGPMCDLLWSDPSEDFGNEKSQEHFSH 259
            ++++  C HGGLSP++ +++ IRR+ R  + P  G +CDLLWSDP      +K    +  
Sbjct: 2202 IDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDP------DKETMGWGE 2041

Query: 260  NTVRGCSYFYNYPAVCEFLQNNNLLSIIRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPN 319
            N  RG S+ +    V +FL  ++L  I RAH+  + GY  + K Q      L+T+FSAPN
Sbjct: 2040 ND-RGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQ------LVTLFSAPN 1882

Query: 320  YLDVYNNKAAVLKYENNVM 338
            Y   ++N  A++  +  +M
Sbjct: 1881 YCGEFDNAGAMMSVDETLM 1825
>06264
          Length = 999

 Score =  219 bits (559), Expect = 2e-57,   Method: Compositional matrix adjust.
 Identities = 107/260 (41%), Positives = 161/260 (61%), Gaps = 1/260 (0%)
 Frame = -3

Query: 80  ILRREKTMIEVEAPITVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYFSIECV 139
           I   +  ++E+EAP+ +CGDIHGQ++DL++LFE GG P  + YLFLGDYVDRG  S+E +
Sbjct: 964 IFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGRQSLETI 785

Query: 140 LYLWVLKILYPSTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYEACMEAFDSLPLAAL 199
             L   KI YP   FLLRGNHEC  +   + F  ECK +Y+ ++++   + F+ LP+AA+
Sbjct: 784 CLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAI 605

Query: 200 LNQQFLCVHGGLSPEIHTLDDIRRLDRFKEPPAFGPMCDLLWSDP-SEDFGNEKSQEHFS 258
           ++++  C HGGLSP++ +++ IRR+ R  + P  G +CDLLWSDP  E  G  +S     
Sbjct: 604 IDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKETMGWGESD---- 437

Query: 259 HNTVRGCSYFYNYPAVCEFLQNNNLLSIIRAHEAQDAGYRMYRKSQTTGFPSLITIFSAP 318
               RG S+ +    V +FL  ++L  I RAH+  + GY  + K Q      L+T+FSAP
Sbjct: 436 ----RGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQ------LVTLFSAP 287

Query: 319 NYLDVYNNKAAVLKYENNVM 338
           NY   ++N  A++  +  +M
Sbjct: 286 NYCGEFDNAGAMMSVDETLM 227
>06084
          Length = 1739

 Score =  184 bits (466), Expect = 9e-47,   Method: Compositional matrix adjust.
 Identities = 100/236 (42%), Positives = 140/236 (59%), Gaps = 1/236 (0%)
 Frame = -2

Query: 101  HGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYFSIECVLYLWVLKILYPSTLFLLRGNH 160
            HGQF+DLM+LF+ GG   +T Y+F+GD+VDRGYFS+E    L  LK  +P  + LLRGNH
Sbjct: 1738 HGQFYDLMELFKTGGEMPDTNYVFMGDFVDRGYFSLETFTLLLTLKAKWPDKIVLLRGNH 1559

Query: 161  ECRHLTEYFTFKQECKIKY-SERVYEACMEAFDSLPLAALLNQQFLCVHGGLSPEIHTLD 219
            E R +T+ + F  EC+ KY +   +  C   FD L +AA++++  LCVHGGLSP+I T+D
Sbjct: 1558 ESRQITQIYGFYDECQTKYGNANAWRYCCRVFDLLTIAAIIDECILCVHGGLSPDIKTID 1379

Query: 220  DIRRLDRFKEPPAFGPMCDLLWSDPSEDFGNEKSQEHFSHNTVRGCSYFYNYPAVCEFLQ 279
             IR ++R +E P  G  CDL+WSDP ED             + RG  + +      EF+ 
Sbjct: 1378 QIRTIERNQEIPHKGAFCDLVWSDP-EDVDTWAM-------SPRGAGWLFGAKVTAEFVA 1223

Query: 280  NNNLLSIIRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKAAVLKYEN 335
            +NNL  I RAH+    GY+     +      L+T++SAPNY     N AAVL + +
Sbjct: 1222 SNNLKLICRAHQLVHEGYKYMFDEK------LVTVWSAPNYCYRCGNIAAVLSFTD 1073
>19040
          Length = 452

 Score =  155 bits (391), Expect = 5e-38,   Method: Composition-based stats.
 Identities = 64/140 (45%), Positives = 96/140 (68%)
 Frame = -3

Query: 80  ILRREKTMIEVEAPITVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYFSIECV 139
           I  ++  ++E+EAP+ +CGDIHGQ+ DL++LFE GG P    YLFLGDYVDRG  S+E +
Sbjct: 423 IFLQQPILLELEAPLIICGDIHGQYTDLLRLFEYGGFPPAANYLFLGDYVDRGKQSLETI 244

Query: 140 LYLWVLKILYPSTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYEACMEAFDSLPLAAL 199
             L   KI YP   FLLRGNHEC  +   + F  ECK +Y+ ++++   + F+ LP+AA+
Sbjct: 243 CLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNVKLWKTFTDCFNCLPVAAI 64

Query: 200 LNQQFLCVHGGLSPEIHTLD 219
           ++++  C HGGLSP++  ++
Sbjct: 63  IDEKIFCCHGGLSPDLQGME 4
>25536
          Length = 486

 Score =  120 bits (300), Expect = 2e-27,   Method: Compositional matrix adjust.
 Identities = 53/107 (49%), Positives = 73/107 (68%)
 Frame = +1

Query: 73  IINEGAAILRREKTMIEVEAPITVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRG 132
           +  +   IL +E  + EV+ P+TVCGD+HGQF DLM+LF +GG   +T YLF+GDYVDRG
Sbjct: 133 LCEKAKEILSKESNVQEVKCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDRG 312

Query: 133 YFSIECVLYLWVLKILYPSTLFLLRGNHECRHLTEYFTFKQECKIKY 179
           Y+S+E V  L  LK+ +   + +LRGNHE R +T+ + F  EC  KY
Sbjct: 313 YYSVETVSLLVALKVRFRDRITILRGNHESRQITQVYGFYDECLRKY 453
>18336
          Length = 465

 Score =  102 bits (254), Expect(3) = 9e-26,   Method: Composition-based stats.
 Identities = 44/81 (54%), Positives = 54/81 (66%)
 Frame = +2

Query: 96  VCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYFSIECVLYLWVLKILYPSTLFL 155
           +CGDIHGQ++DL++LFE GG P  + YLFLGDYVDRG  S+E +  L   KI YP   FL
Sbjct: 104 ICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFL 283

Query: 156 LRGNHECRHLTEYFTFKQECK 176
           LRGNHEC  +   + F    K
Sbjct: 284 LRGNHECASINRIYGFMMNAK 346

 Score = 29.3 bits (64), Expect(3) = 9e-26,   Method: Composition-based stats.
 Identities = 10/34 (29%), Positives = 23/34 (67%)
 Frame = +1

Query: 174 ECKIKYSERVYEACMEAFDSLPLAALLNQQFLCV 207
           ECK +Y+ ++++   + F+ LP+AA+++ +   V
Sbjct: 337 ECKRRYNIKLWKTFTDCFNCLPIAAIIDVKIFVV 438

 Score = 23.5 bits (49), Expect(3) = 9e-26,   Method: Compositional matrix adjust.
 Identities = 8/11 (72%), Positives = 10/11 (90%)
 Frame = +3

Query: 205 LCVHGGLSPEI 215
           LC HGGLSP++
Sbjct: 429 LCCHGGLSPDL 461
>36367
          Length = 827

 Score = 65.5 bits (158), Expect = 5e-11,   Method: Compositional matrix adjust.
 Identities = 46/155 (29%), Positives = 75/155 (48%), Gaps = 13/155 (8%)
 Frame = +1

Query: 208 HGGL-SPEIHTLDDIRRLDR----FKEPPAFGPMC-DLLWSDP-------SEDFGNEKSQ 254
           HGG+ SPE      +  +++      +P    PM  ++LWSDP        E   + K  
Sbjct: 1   HGGIPSPENEGGGHLEAINKIPVPLSDPEVDSPMAWEILWSDPISVDLVSPEVLKDMKEH 180

Query: 255 EHFSHNTVRGCSYFYNYPAVCEFLQNNNLLSIIRAHEAQDAGYRMYRKSQTTGFPSLITI 314
             F+ N+ RG ++F++  A+  FL+ N L  +IRAHE Q+ G+++ ++ +      L+T+
Sbjct: 181 HGFTFNSRRGTAHFFSCNALLAFLERNGLSHVIRAHEVQEVGFQVQQQGK------LLTV 342

Query: 315 FSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHP 349
           FS+  Y    N  A VL     +  IR     P P
Sbjct: 343 FSSSRYCGGSNEAACVLADNYKLRMIRIDTT*PGP 447
>04295
          Length = 748

 Score = 45.1 bits (105), Expect = 7e-05,   Method: Compositional matrix adjust.
 Identities = 22/65 (33%), Positives = 36/65 (55%)
 Frame = -1

Query: 274 VCEFLQNNNLLSIIRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKAAVLKY 333
           V +FL  ++L  I RAH+  + GY  + K Q      L+T+FSAPNY   ++N   ++  
Sbjct: 739 VSKFLNRHDLDLITRAHQVVEDGYEFFAKRQ------LVTLFSAPNYCGEFDNAGGMMSV 578

Query: 334 ENNVM 338
           +  +M
Sbjct: 577 DETLM 563
>21146
          Length = 408

 Score = 39.7 bits (91), Expect = 0.003,   Method: Composition-based stats.
 Identities = 23/58 (39%), Positives = 27/58 (46%)
 Frame = +3

Query: 234 GPMCDLLWSDPSEDFGNEKSQEHFSHNTVRGCSYFYNYPAVCEFLQNNNLLSIIRAHE 291
           GPMCDLLWSDP +  G   S         RG  Y +       F  +N L  I RAH+
Sbjct: 117 GPMCDLLWSDPDDRGGWGISP--------RGAGYTFGQDISETFNHSNGLTLISRAHQ 266
>30980
          Length = 765

 Score = 33.5 bits (75), Expect = 0.22,   Method: Compositional matrix adjust.
 Identities = 23/72 (31%), Positives = 38/72 (52%), Gaps = 1/72 (1%)
 Frame = +3

Query: 277 FLQNNNLLSIIRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKAAVLKYENN 336
           F  +N L  I RAH+    GY            +++TIFSAPNY     N+AA+++ ++ 
Sbjct: 6   FNHSNGLTLISRAHQLVMEGYNWCHDR------NVVTIFSAPNYCYRCGNQAAIMELDDA 167

Query: 337 V-MNIRQFNCSP 347
           +  +  QF+ +P
Sbjct: 168 LKYSFLQFDPAP 203
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|21703344|ref|NP_033146.1| SAR1a gene homolog [Mus
musculus]
         (198 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

11378                                                                 296   3e-81
15662                                                                 172   6e-44
18949                                                                 127   2e-30
09827                                                                  95   2e-20
08153                                                                  92   9e-20
10862                                                                  72   7e-17
33605                                                                  71   4e-13
18208                                                                  62   1e-10
15973                                                                  52   2e-07
11965                                                                  36   0.010
19006                                                                  35   0.016
36734                                                                  34   0.036
19506                                                                  33   0.099
26083                                                                  32   0.22 
29196                                                                  31   0.37 
11728                                                                  30   0.54 
22530                                                                  29   1.2  
03745                                                                  29   1.3  
17511                                                                  27   4.2  
>11378
          Length = 1688

 Score =  296 bits (758), Expect = 3e-81,   Method: Compositional matrix adjust.
 Identities = 137/191 (71%), Positives = 161/191 (84%)
 Frame = +3

Query: 8   IYNGFSSVLQFLGLYKKSGKLVFLGLDNAGKTTLLHMLKDDRLGQHVPTLHPTSEELTIA 67
           ++N F  +L FLGLYKKSGKLVFLGLDNAGKTTLLHMLKDD++ QHVPTLHPTSEEL++ 
Sbjct: 270 LWNWFQDMLSFLGLYKKSGKLVFLGLDNAGKTTLLHMLKDDKMAQHVPTLHPTSEELSMG 449

Query: 68  GMTFTTFDLGGHEQARRVWKNYLPAINGIVFLVDCADHSRLMESKVELNALMTDETISNV 127
           GM FTTFDLGGH QARRVWK+Y PA++GIVFLVD  D  RL+E+K EL++LMTDE ++N 
Sbjct: 450 GMRFTTFDLGGHRQARRVWKDYFPAVDGIVFLVDVHDRERLVEAKAELDSLMTDEQVANA 629

Query: 128 PILILGNKIDRTDAISEEKLREIFGLYGQTTGKGNVTLKELNARPMEVFMCSVLKRQGYG 187
           PIL+LGNKID+  A SEE++R  FGL   TTGKG V   EL  RPME+FMCSVLKRQGYG
Sbjct: 630 PILVLGNKIDKPGAASEEEIRHWFGLNSLTTGKGTVARGELPGRPMELFMCSVLKRQGYG 809

Query: 188 EGFRWLSQYID 198
           EGFRW++QYI+
Sbjct: 810 EGFRWMAQYIN 842
>15662
          Length = 455

 Score =  172 bits (437), Expect = 6e-44,   Method: Compositional matrix adjust.
 Identities = 76/118 (64%), Positives = 97/118 (82%)
 Frame = +2

Query: 81  QARRVWKNYLPAINGIVFLVDCADHSRLMESKVELNALMTDETISNVPILILGNKIDRTD 140
           QARRVWK+Y PA++GIVFLVD  D  R +E+K EL++LMTDE ++N PIL+LGNKID+  
Sbjct: 2   QARRVWKDYFPAVDGIVFLVDVHDRERFVEAKAELDSLMTDEQVANAPILVLGNKIDKPG 181

Query: 141 AISEEKLREIFGLYGQTTGKGNVTLKELNARPMEVFMCSVLKRQGYGEGFRWLSQYID 198
           A SE+++R  FGL+  TTGKG V+  EL  RP+E+FMCSVLKRQGYGEGFRW++QYI+
Sbjct: 182 AASEDEIRHWFGLHSLTTGKGTVSRGELPGRPLELFMCSVLKRQGYGEGFRWMAQYIN 355
>18949
          Length = 414

 Score =  127 bits (320), Expect = 2e-30,   Method: Compositional matrix adjust.
 Identities = 54/87 (62%), Positives = 73/87 (83%)
 Frame = +3

Query: 52  QHVPTLHPTSEELTIAGMTFTTFDLGGHEQARRVWKNYLPAINGIVFLVDCADHSRLMES 111
           QH PT  PTSEEL++ GMTFTTFDLGGH QARRVWK+Y PA++GIVF+VD  D  R+ E+
Sbjct: 6   QHRPTGLPTSEELSMGGMTFTTFDLGGHRQARRVWKDYFPAVDGIVFIVDVHDTERITEA 185

Query: 112 KVELNALMTDETISNVPILILGNKIDR 138
           K EL++L+ D+ I+++P+L+LGNK+D+
Sbjct: 186 KAELDSLLRDDQIADIPVLVLGNKMDK 266

 Score = 55.8 bits (133), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 30/64 (46%), Positives = 38/64 (59%)
 Frame = +2

Query: 125 SNVPILILGNKIDRTDAISEEKLREIFGLYGQTTGKGNVTLKELNARPMEVFMCSVLKRQ 184
           S  P +  G +  +     EE +R   GLY  TTGK   +  EL  RP+E+FMCSV+KRQ
Sbjct: 224 SGHPRVGAGQQDGQAWGGGEEDVRHWLGLY-STTGKDKESDSELTGRPVELFMCSVVKRQ 400

Query: 185 GYGE 188
           GYGE
Sbjct: 401 GYGE 412
>09827
          Length = 1201

 Score = 94.7 bits (234), Expect = 2e-20,   Method: Compositional matrix adjust.
 Identities = 55/197 (27%), Positives = 99/197 (50%)
 Frame = -3

Query: 1    MSFIFEWIYNGFSSVLQFLGLYKKSGKLVFLGLDNAGKTTLLHMLKDDRLGQHVPTLHPT 60
            M   F+ I++G S +       KK  +++ +GLD AGKTT+L+ LK   +   +PT+   
Sbjct: 1172 MGNAFQKIFSGLSFMFG-----KKDMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFN 1008

Query: 61   SEELTIAGMTFTTFDLGGHEQARRVWKNYLPAINGIVFLVDCADHSRLMESKVELNALMT 120
             E +    ++FT +D+GG ++ R +W++Y     G++F+VD  D  R+ E++ EL  ++ 
Sbjct: 1007 VETVEYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDKERVQEAREELTRMLN 828

Query: 121  DETISNVPILILGNKIDRTDAISEEKLREIFGLYGQTTGKGNVTLKELNARPMEVFMCSV 180
            ++ + +  +L+  NK D   A++  ++ E  GL+G            L  R   +     
Sbjct: 827  EDELRDAVLLVFANKQDLPHAMATAEITEKLGLHG------------LRNRTWYIQSTCA 684

Query: 181  LKRQGYGEGFRWLSQYI 197
                G  EG  WLS  +
Sbjct: 683  TTGDGLYEGLDWLSNQL 633
>08153
          Length = 1703

 Score = 92.4 bits (228), Expect = 9e-20,   Method: Compositional matrix adjust.
 Identities = 56/186 (30%), Positives = 96/186 (51%), Gaps = 2/186 (1%)
 Frame = +1

Query: 11  GFSSVLQFLGLYKKSGKLVFLGLDNAGKTTLLHMLKDDRLGQHVPTLHPTSEELTIAGMT 70
           GF S+ + L   KK  +++ +GLD AGKTT+L+ LK   +   +PT+    E +    ++
Sbjct: 43  GFVSLFKNL-FGKKEVRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNIS 219

Query: 71  FTTFDLGGHEQARRVWKNYLPAINGIVFLVDCADHSRLMESKVELNALMTDETISNVPIL 130
           FT +D+GG ++ R +W++Y     G++F+VD  D  R+ E+K EL  ++ ++ + +  IL
Sbjct: 220 FTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERINEAKEELARMLNEDDLRDAIIL 399

Query: 131 ILGNKIDRTDAISEEKLREIFGLYGQTTGKGNVTLKELNARPMEVFMCSVLKRQGYG--E 188
           +  NK D  +A S  ++    GL               N +  + +M +     G G  E
Sbjct: 400 VFANKQDLPNAYSASEVTAHLGL--------------ANLKGRKWYMQATCATSGDGMYE 537

Query: 189 GFRWLS 194
           G  WLS
Sbjct: 538 GLEWLS 555
>10862
          Length = 2896

 Score = 72.0 bits (175), Expect(2) = 7e-17,   Method: Compositional matrix adjust.
 Identities = 30/83 (36%), Positives = 52/83 (62%)
 Frame = -3

Query: 71   FTTFDLGGHEQARRVWKNYLPAINGIVFLVDCADHSRLMESKVELNALMTDETISNVPIL 130
            F  +D+GG ++ R +W++Y     G++F+VDCAD  R+ E++ EL+ ++ D  + +  IL
Sbjct: 2480 FNVWDVGGQDKIRPLWRHYYTGTQGLIFVVDCADRDRIDEARQELHRIINDREMRDAIIL 2301

Query: 131  ILGNKIDRTDAISEEKLREIFGL 153
            I  NK D  DA+   +++E  GL
Sbjct: 2300 IFANKQDLPDAMKPHEIQEKLGL 2232

 Score = 31.6 bits (70), Expect(2) = 7e-17,   Method: Compositional matrix adjust.
 Identities = 20/37 (54%), Positives = 25/37 (67%)
 Frame = -1

Query: 24   KSGKLVFLGLDNAGKTTLLHMLKDDRLGQHVPTLHPT 60
            K  +++ LGLD AGKTTLL+ +K   LGQ V T  PT
Sbjct: 2620 KEMRILMLGLDAAGKTTLLYKMK---LGQSV-TXIPT 2522
>33605
          Length = 888

 Score = 70.9 bits (172), Expect = 4e-13,   Method: Compositional matrix adjust.
 Identities = 35/102 (34%), Positives = 57/102 (55%)
 Frame = +1

Query: 11  GFSSVLQFLGLYKKSGKLVFLGLDNAGKTTLLHMLKDDRLGQHVPTLHPTSEELTIAGMT 70
           G  ++L+ +   +K  +L+ LGLDNAGKTT+L     + +    PTL    + L   G  
Sbjct: 454 GLLTILKKMKQKEKEVRLLMLGLDNAGKTTILKKFNGEDIDTISPTLGFNIKTLEHRGFK 633

Query: 71  FTTFDLGGHEQARRVWKNYLPAINGIVFLVDCADHSRLMESK 112
              +D+GG +  R  W+NY  + +G+V++VD AD  R+ + K
Sbjct: 634 LNVWDVGGQQSLRSYWRNYFESTDGLVWVVDSADRMRIADCK 759
>18208
          Length = 458

 Score = 62.0 bits (149), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 29/87 (33%), Positives = 47/87 (54%)
 Frame = -1

Query: 27  KLVFLGLDNAGKTTLLHMLKDDRLGQHVPTLHPTSEELTIAGMTFTTFDLGGHEQARRVW 86
           +++ LGLDNAGKTTLL  L  +      PT     + +   G     +D+GG  + R  W
Sbjct: 296 RILLLGLDNAGKTTLLKQLASEDPSHITPTQGFNIKSVQSKGFKLNVWDIGGQRRIRPYW 117

Query: 87  KNYLPAINGIVFLVDCADHSRLMESKV 113
           KNY    + +++++D +D  R+ E+ V
Sbjct: 116 KNYFENTDLLIYVIDSSDTKRMEETGV 36
>15973
          Length = 493

 Score = 51.6 bits (122), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 30/108 (27%), Positives = 53/108 (49%)
 Frame = -1

Query: 89  YLPAINGIVFLVDCADHSRLMESKVELNALMTDETISNVPILILGNKIDRTDAISEEKLR 148
           Y   +N IV++VD AD  +L  S+ EL+ L+    +  VP+L+LGNK D   A+ E++L 
Sbjct: 487 YCRGVNAIVYMVDAADQDKLEASRNELHNLLDKPQLQGVPVLVLGNKRDLPGALDEKELI 308

Query: 149 EIFGLYGQTTGKGNVTLKELNARPMEVFMCSVLKRQGYGEGFRWLSQY 196
           +             + L  +  R +  +  S  +++      +WL Q+
Sbjct: 307 D------------RMNLSAIQDREICCYSISCKEKENIDITLQWLIQH 200
>11965
          Length = 3256

 Score = 36.2 bits (82), Expect = 0.010,   Method: Compositional matrix adjust.
 Identities = 29/135 (21%), Positives = 56/135 (41%), Gaps = 10/135 (7%)
 Frame = +1

Query: 25  SGKLVFLGLDNAGKTTLLHMLKDDRLGQHVPTLHPTSEELTIAGMTFTTFDLGGHEQARR 84
           S K     LD  G    +   + D L   V T        +   + F  FD+GG    R+
Sbjct: 55  SAKYFLDDLDRLGTKDYMPT-EQDILRTRVKTTGIVEVHFSFKNLNFKLFDVGGQRSERK 231

Query: 85  VWKNYLPAINGIVFLVDCADH----------SRLMESKVELNALMTDETISNVPILILGN 134
            W +    +  I+F V  +++          +R+ ES    +++  ++  ++  I++  N
Sbjct: 232 KWIHCFEDVTAIIFCVAMSEYDQVLHEDETTNRMQESLKLFDSICNNKWFTDTSIILFLN 411

Query: 135 KIDRTDAISEEKLRE 149
           K D    + EEK+++
Sbjct: 412 KKD----LFEEKIKK 444
>19006
          Length = 568

 Score = 35.4 bits (80), Expect = 0.016,   Method: Compositional matrix adjust.
 Identities = 38/135 (28%), Positives = 62/135 (45%), Gaps = 7/135 (5%)
 Frame = -2

Query: 20  GLYKKSGKLVFLGLDNAGKTTLLHMLKDDRLGQ-HVPTL---HPTSEELTIAGMTFTTFD 75
           G +K+  KLV +G    GKT LL +   D+  + +VPT+   +    E+    +    +D
Sbjct: 447 GCHKE--KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDSKQVELALWD 274

Query: 76  LGGHEQARRVWKNYLPAINGIV--FLVDCADHSRLMESKVELNALMTDETISNVPILILG 133
             G E   R+     P  + I+  F +D  D    +E+  E           NVPI+++G
Sbjct: 273 TAGQEDYDRLRPLSYPDTDVILMCFSIDSPDS---LENIPEKWTPEVRHFCPNVPIILVG 103

Query: 134 NKID-RTDAISEEKL 147
           NK D R D  ++ +L
Sbjct: 102 NKKDLRNDENTKREL 58
>36734
          Length = 170

 Score = 34.3 bits (77), Expect = 0.036,   Method: Composition-based stats.
 Identities = 12/14 (85%), Positives = 14/14 (100%)
 Frame = -3

Query: 184 QGYGEGFRWLSQYI 197
           QGYGEGFRWL++YI
Sbjct: 144 QGYGEGFRWLARYI 103
>19506
          Length = 421

 Score = 32.7 bits (73), Expect = 0.099,   Method: Compositional matrix adjust.
 Identities = 17/42 (40%), Positives = 25/42 (59%)
 Frame = -3

Query: 23  KKSGKLVFLGLDNAGKTTLLHMLKDDRLGQHVPTLHPTSEEL 64
           +K   +++ GLD AGKTTLL+ LK   +   +PT+    E L
Sbjct: 143 QKPVTVIYFGLDAAGKTTLLYNLKLGEVVTTIPTIGFNVETL 18
>26083
          Length = 432

 Score = 31.6 bits (70), Expect = 0.22,   Method: Compositional matrix adjust.
 Identities = 29/114 (25%), Positives = 54/114 (47%), Gaps = 5/114 (4%)
 Frame = +1

Query: 27  KLVFLGLDNAGKTTLLHMLKDDRLG---QHVPTLHPTSEELTIAGMT--FTTFDLGGHEQ 81
           KLVFLG  + GKT+L+     D      Q    +   S+ + +   T     +D  G E+
Sbjct: 82  KLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTIRLQLWDTAGQER 261

Query: 82  ARRVWKNYLPAINGIVFLVDCADHSRLMESKVELNALMTDETISNVPILILGNK 135
            R +  +Y+   +  V + D  + +   ++   ++ + T E  S+V I+++GNK
Sbjct: 262 FRSLIPSYIRDSSVAVVVYDITNANSFHQTSKWIDDVRT-ERGSDVIIMLVGNK 420
>29196
          Length = 431

 Score = 30.8 bits (68), Expect = 0.37,   Method: Compositional matrix adjust.
 Identities = 10/44 (22%), Positives = 23/44 (52%)
 Frame = -2

Query: 66  IAGMTFTTFDLGGHEQARRVWKNYLPAINGIVFLVDCADHSRLM 109
           +  + F  FD+GG    R+ W +    +  I+F V  +++ +++
Sbjct: 232 LKNLNFKLFDVGGQRSERKKWIHCFEDVTAIIFCVAMSEYDQVL 101
>11728
          Length = 635

 Score = 30.4 bits (67), Expect = 0.54,   Method: Compositional matrix adjust.
 Identities = 38/164 (23%), Positives = 68/164 (41%), Gaps = 5/164 (3%)
 Frame = -1

Query: 27  KLVFLGLDNAGKTTLLHMLKDDRL-GQHVPTL---HPTSEELTIAGMTFTTFDLGGHEQA 82
           K V +G    GKT LL     +   G+++PT+   +  +  +    +    +D  G E  
Sbjct: 485 KCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDSKPINLGLWDTAGQEDY 306

Query: 83  RRVWKNYLPAINGIVFLVDCADHSRLMESKVELNALMTDETISNVPILILGNKID-RTDA 141
            R+     P  +  +        +     K +    ++     N PI+++G K+D R D 
Sbjct: 305 DRLRPLSYPQTDVFLICFSLISPASFENVKAKWYPEVSHHC-PNTPIILVGTKLDLREDK 129

Query: 142 ISEEKLREIFGLYGQTTGKGNVTLKELNARPMEVFMCSVLKRQG 185
            + EKL+E   L   T  +G    K++ A   +   CS L ++G
Sbjct: 128 ETIEKLKEK-KLAPITYPQGLAMAKDIGAG--KYLECSALTQKG 6
>22530
          Length = 1070

 Score = 28.9 bits (63), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 14/33 (42%), Positives = 17/33 (51%)
 Frame = +2

Query: 47  DDRLGQHVPTLHPTSEELTIAGMTFTTFDLGGH 79
           D  LG H+P   P  EE+ +A    T FDL  H
Sbjct: 743 DGFLGPHLPLKEPKWEEIPLANTHGTVFDLNFH 841
>03745
          Length = 1266

 Score = 28.9 bits (63), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 15/36 (41%), Positives = 20/36 (55%), Gaps = 2/36 (5%)
 Frame = -1

Query: 75  DLGGHEQARRVWKNYLPAINGI--VFLVDCADHSRL 108
           D  G  + RR W +YLP    +  VFL+ CA H+ L
Sbjct: 633 DFAGVGRHRRSWLHYLPFFITVRRVFLLXCAPHNVL 526
>17511
          Length = 483

 Score = 27.3 bits (59), Expect = 4.2,   Method: Compositional matrix adjust.
 Identities = 26/119 (21%), Positives = 55/119 (46%), Gaps = 8/119 (6%)
 Frame = -3

Query: 27  KLVFLGLDNAGKTTLLHMLKDDRLG-QHVPTLHPT--SEELTIAG--MTFTTFDLGGHEQ 81
           K++ LG    GKT+L++   + +   Q+  T+     ++E+ +    +T   +D  G E+
Sbjct: 361 KVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQIWDTAGQER 182

Query: 82  ARRVWKNYLPAINGIVFLVDCA--DHSRLMES-KVELNALMTDETISNVPILILGNKID 137
            + +   +    +  V + D    +  R ++S + E     +     N P +++GNKID
Sbjct: 181 FQSLGVAFYRGADCCVLVFDVTMPNTFRSLDSWRDEFLIQASPRDPENFPFVVIGNKID 5
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6679082|ref|NP_032733.1| N-myristoyltransferase 1
[Mus musculus]
         (496 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

21849                                                                 243   3e-81
11998                                                                  29   4.4  
33365                                                                  28   9.5  
>21849
          Length = 912

 Score =  243 bits (620), Expect(3) = 3e-81,   Method: Compositional matrix adjust.
 Identities = 111/177 (62%), Positives = 141/177 (79%)
 Frame = -2

Query: 270 RVHLEGIFQAVYTAGVVLPKPVGTCRYWHRSLNPRKLIEVKFSHLSRNMTMQRTMKLYRL 329
           RVH +G+FQAVYTAGVVLPKPV +CRYWHRSLNPRKLIEVKFSHLSRNMTMQRT+KLY+L
Sbjct: 911 RVHQQGLFQAVYTAGVVLPKPVASCRYWHRSLNPRKLIEVKFSHLSRNMTMQRTLKLYKL 732

Query: 330 PETPKTAGLRPMEKKDIPVVHQLLSRYLKQFHLTPVMNQEEVEHWFYPQENIIDTFVVEN 389
           P+ PKT G R     D+     L+ +Y+++F L PV +++E  HWF P+E+I++++VVE 
Sbjct: 731 PDVPKTPGFRKFTPADVTETFNLVCKYMQKFDLAPVFSEDEFRHWFIPREHIVNSYVVET 552

Query: 390 ANGEVTDFLSFYTLPSTIMNHPTHKSLKAAYSFYNVHTQTPLLDLMSDALVLAKMKG 446
            +G +TDF+SFY+LPSTIM+HPTHK L+AAYSFYNV   T   +LM DAL++A   G
Sbjct: 551 -DGVITDFVSFYSLPSTIMHHPTHKLLRAAYSFYNVSVATAWAELMQDALIVANKFG 384

 Score = 60.8 bits (146), Expect(3) = 3e-81,   Method: Compositional matrix adjust.
 Identities = 26/33 (78%), Positives = 29/33 (87%)
 Frame = -1

Query: 464 KLKFGIGDGNLQYYLYNWKCPSMGAEKVGLVLQ 496
           KLKFG+GDG LQYYLYNWKCP+M   +VGLVLQ
Sbjct: 333 KLKFGVGDGFLQYYLYNWKCPAMETNRVGLVLQ 235

 Score = 38.5 bits (88), Expect(3) = 3e-81,   Method: Compositional matrix adjust.
 Identities = 17/18 (94%), Positives = 17/18 (94%)
 Frame = -3

Query: 446 GFDVFNALDLMENKTFLE 463
           GFDVFNALDLMENK FLE
Sbjct: 385 GFDVFNALDLMENKEFLE 332
>11998
          Length = 1292

 Score = 28.9 bits (63), Expect = 4.4,   Method: Compositional matrix adjust.
 Identities = 13/43 (30%), Positives = 22/43 (51%)
 Frame = +1

Query: 351 QLLSRYLKQFHLTPVMNQEEVEHWFYPQENIIDTFVVENANGE 393
            L+S YLK F    ++N E + H+F+   +       E+ NG+
Sbjct: 202 HLISTYLKIFGFWTILNLETIHHFFFQTMDASRAHKTESMNGK 330
>33365
          Length = 488

 Score = 28.1 bits (61), Expect = 9.5,   Method: Composition-based stats.
 Identities = 15/43 (34%), Positives = 20/43 (46%)
 Frame = -2

Query: 101 VGQGPAKTMEEASKRSYQFWDTQPVPKLGEVVNTHGPVEPDKD 143
           V  G  +    A +  +  WD   + KL  VV+ HGPV   KD
Sbjct: 385 VDGGADELFAPAHRLHFLHWDDDLLRKLDHVVHPHGPVGEXKD 257
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|94396017|ref|XP_985378.1| PREDICTED: similar to
Protein CXorf17 homolog [Mus musculus]
         (1231 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

01750                                                                 300   3e-81
23948                                                                  72   1e-12
15118                                                                  34   0.42 
19650                                                                  29   9.8  
>01750
          Length = 1886

 Score =  300 bits (767), Expect = 3e-81,   Method: Compositional matrix adjust.
 Identities = 163/415 (39%), Positives = 237/415 (57%), Gaps = 3/415 (0%)
 Frame = +2

Query: 665  LPPVAPEVLRVAEHRHKKGLMYPYIFHILTKGEIKIAVSIEDEANKDLPPAALLYRPVRQ 724
             P V  E+L +A  RHKKGLM+P I+ +L++GE+K+ V++EDE  ++LP    ++RPVRQ
Sbjct: 203  FPTVTTEILNIASDRHKKGLMHPMIYQLLSQGEVKLPVTLEDEVAQELPSYTDVFRPVRQ 382

Query: 725  YVYGVLFSLAESRKKTERLAFRKNRLPPEFS-PLIIKEWAAYKGKSPQTPELVEALAFRE 783
             +Y VLF+L + +   E     K   PP+ +  + +KEW   +  +    + V A    +
Sbjct: 383  SIYSVLFNLNKLKIVHETTYKEKGETPPKRAFDVAVKEWVVQQNSNRPVYKTVVARPV-D 559

Query: 784  WTCPNLKRLWLGKAVEDKNRRMRAFLACMRSDTPAMLNPANVPTHLMVLCCVLRYMVQWP 843
            W  P+++R+WLGK+ EDKNRR+RAFL  M SD+  +LN   VP HL+++ CVLRY++Q+ 
Sbjct: 560  WKVPSIERMWLGKSDEDKNRRLRAFLTIMHSDSNLVLNTQYVPQHLLLMVCVLRYIMQY- 736

Query: 844  GARILRRQELDAFLAQALSPKLYEPDQLQELKIDNLDPRGIQLSALFMSGVDMALFANDA 903
              ++L+R ELDAFLA  +S  L++   +Q+LK+  +  RG+QL++LFMSG++ AL AND 
Sbjct: 737  -GQVLQRHELDAFLAMGVSSLLHDEQTMQDLKLPTIVGRGVQLASLFMSGIETALLANDV 913

Query: 904  CGQPIPWEHCCPWMYFDGKLFQSKLLKASREKTPLIDLCDGQAEQAAKVEKMRQSILEGL 963
            CG P+P   C PW++FDGKLF  KLLKA+   T L+DLCDGQ EQ  ++E++RQS+LE L
Sbjct: 914  CGAPVPAAMCTPWLFFDGKLFHYKLLKAN-GNTSLVDLCDGQMEQVMRLERLRQSVLENL 1090

Query: 964  --SFSRQNHXXXXXXXXXXXXXXXSVYPRHFGPVPPSQXXXXXXXXXXXXXXXXXETVAT 1021
               F+R                     P  + P  P                        
Sbjct: 1091 HVDFARPQLPGFYPPYPEPYRPGPGSGPGSYRPSGP------------------------ 1198

Query: 1022 GPYRAFRVTAASGHCGAFSGSDSSRTSKSQGGVQPIPSQGGKLEIAGTVVGHWAG 1076
            GP    R +   G     +G       +   G  P+ ++GG LEIAGTVVG W G
Sbjct: 1199 GPMYRGRGSGPMGPTPGHAGPRPLGRGRGILGSCPLDNRGGHLEIAGTVVGSWRG 1363
>23948
          Length = 387

 Score = 72.4 bits (176), Expect = 1e-12,   Method: Compositional matrix adjust.
 Identities = 31/51 (60%), Positives = 40/51 (78%)
 Frame = +2

Query: 913 CCPWMYFDGKLFQSKLLKASREKTPLIDLCDGQAEQAAKVEKMRQSILEGL 963
           C PW++FDGKLF  KLLKA+   T L+DLCDGQ EQ  ++E++RQS+LE L
Sbjct: 89  CTPWLFFDGKLFHYKLLKAN-XNTSLVDLCDGQMEQVMRLERLRQSVLENL 238
>15118
          Length = 1074

 Score = 33.9 bits (76), Expect = 0.42,   Method: Composition-based stats.
 Identities = 22/85 (25%), Positives = 37/85 (43%)
 Frame = +1

Query: 756 PLIIKEWAAYKGKSPQTPELVEALAFREWTCPNLKRLWLGKAVEDKNRRMRAFLACMRSD 815
           P  I  W A       T   + +L  R+WT   +  +WL   V D    +  F+ C + +
Sbjct: 1   PWEITSWTA---SGSTTAHSIASLRHRQWTYHRVATMWLWATVPD----IWTFITCNQEN 159

Query: 816 TPAMLNPANVPTHLMVLCCVLRYMV 840
             A   P+ + +H+ V+C   R M+
Sbjct: 160 IAA---PSVILSHMSVVCVAWRSML 225
>19650
          Length = 625

 Score = 29.3 bits (64), Expect = 9.8,   Method: Compositional matrix adjust.
 Identities = 13/28 (46%), Positives = 15/28 (53%)
 Frame = -1

Query: 763 AAYKGKSPQTPELVEALAFREWTCPNLK 790
           AA    SP TP L    ++R WTCP L 
Sbjct: 454 AACLSPSPHTPSLTRGPSWRPWTCPPLS 371
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6755348|ref|NP_035415.1| retinitis pigmentosa GTpase
regulator [Mus musculus]
         (746 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

02938                                                                 298   5e-81
26574                                                                  53   4e-07
20162                                                                  52   6e-07
12101                                                                  52   7e-07
39525                                                                  37   0.033
03352                                                                  36   0.062
04349                                                                  32   1.2  
03731                                                                  30   2.9  
>02938
          Length = 1718

 Score =  298 bits (763), Expect = 5e-81,   Method: Compositional matrix adjust.
 Identities = 146/316 (46%), Positives = 211/316 (66%), Gaps = 1/316 (0%)
 Frame = +3

Query: 93  KLYMFGSNNWGQLGLGSKAAIIKPTCIKALKPEKVKLAACGRNHTLVSTDTGGVYAAGGN 152
           +++MFG N++GQLG+G++    +P+C+K+LK EK +L ACGR+HT+V+T++G +YA G N
Sbjct: 18  RVFMFGPNDYGQLGIGAQKVANRPSCVKSLKHEKARLVACGRSHTIVATESGNIYAFGAN 197

Query: 153 NEGQLGLGDTDDRDTFHQIVFFTPADTIKQLSAGANTSAALTEDGKLFMWGDNSEGQIGL 212
            EGQLG+    + +   Q+     A   K L+AG + S ALTEDG++F+WG N EGQ+G+
Sbjct: 198 GEGQLGVEGVTETNLPKQVDSLQ-ATPWKMLAAGCDHSLALTEDGRVFVWGGNGEGQLGM 374

Query: 213 EDKSNVCIPHEVTVGKPISWISCGYYHSAFVTMDGELYTFGEPENGKLGLPNELLMNHRS 272
            + S++ +P ++ VG+ ++ I+ GYYHSA VT  GELYTFGE + GKLGL N      ++
Sbjct: 375 GEDSDIPVPRQLDVGQSVACIASGYYHSALVTESGELYTFGESDGGKLGL-NGDTDECKT 551

Query: 273 PQRVLGIPERVIQVACGGGHTVVLTEK-VVYAXXXXXXXXXXXXXXXXETSEPKIIERIK 331
           PQ+V+ I ++V  V+CGG HTV LTEK  VYA                E+  P +++   
Sbjct: 552 PQQVMAINDKVKSVSCGGSHTVALTEKGEVYAFGEGSSGQLGLGVSTLESESPSLLKL-- 725

Query: 332 DQKICHISCGENHTALMTELGLLYTFGDGRHGKLGLGMENFTNQFFPTLCSNFLRFAVQL 391
             K+  + CGEN T +++E G LYTFGDGRHGKL LG E+F+NQF  T    FL+F V+ 
Sbjct: 726 PFKVAQVCCGENFTTVVSERGQLYTFGDGRHGKLALGQESFSNQFVCTKVDRFLKFNVKK 905

Query: 392 IACGGCHMLVFATPRL 407
            ACGGCH++V A+P+L
Sbjct: 906 AACGGCHLIVMASPKL 953

 Score = 43.1 bits (100), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 34/112 (30%), Positives = 51/112 (45%), Gaps = 5/112 (4%)
 Frame = +3

Query: 78  LSCGDEHTAIVTGNNKLYMFGSNNWGQLGLGSKAAIIKPTCIKALKPEK--VKLAACGRN 135
           + CG+  T +V+   +LY FG    G+L LG ++   +  C K  +  K  VK AACG  
Sbjct: 744 VCCGENFTTVVSERGQLYTFGDGRHGKLALGQESFSNQFVCTKVDRFLKFNVKKAACGGC 923

Query: 136 HTLVSTD---TGGVYAAGGNNEGQLGLGDTDDRDTFHQIVFFTPADTIKQLS 184
           H +V        G  A+    EGQ+ +  T  RD+      F+  D  +  S
Sbjct: 924 HLIVMASPKLENGDVASEDEEEGQIMMNGT-IRDSLSLTRTFSARDRRRNAS 1076
>26574
          Length = 441

 Score = 53.1 bits (126), Expect = 4e-07,   Method: Composition-based stats.
 Identities = 26/67 (38%), Positives = 41/67 (61%)
 Frame = +3

Query: 97  FGSNNWGQLGLGSKAAIIKPTCIKALKPEKVKLAACGRNHTLVSTDTGGVYAAGGNNEGQ 156
           +G  ++ +LG G+   + +P  + AL+ +KV   ACG  H +  TD+G V+  G N+EGQ
Sbjct: 6   WGKGDYHRLGHGTDDHVRRPRRVSALQGKKVIDVACGSLHCVACTDSGEVFTWGDNDEGQ 185

Query: 157 LGLGDTD 163
           LG G T+
Sbjct: 186 LGDGTTN 206

 Score = 50.8 bits (120), Expect = 2e-06,   Method: Composition-based stats.
 Identities = 23/63 (36%), Positives = 38/63 (60%)
 Frame = +3

Query: 76  ICLSCGDEHTAIVTGNNKLYMFGSNNWGQLGLGSKAAIIKPTCIKALKPEKVKLAACGRN 135
           I ++CG  H    T + +++ +G N+ GQLG G+  AI +P  + AL+ +K+   ACG  
Sbjct: 99  IDVACGSLHCVACTDSGEVFTWGDNDEGQLGDGTTNAIQRPRMVAALQGKKINRVACGSA 278

Query: 136 HTL 138
           H+L
Sbjct: 279 HSL 287

 Score = 47.0 bits (110), Expect = 3e-05,   Method: Composition-based stats.
 Identities = 22/81 (27%), Positives = 42/81 (51%)
 Frame = +3

Query: 324 PKIIERIKDQKICHISCGENHTALMTELGLLYTFGDGRHGKLGLGMENFTNQFFPTLCSN 383
           P+ +  ++ +K+  ++CG  H    T+ G ++T+GD   G+LG G  N   +  P + + 
Sbjct: 63  PRRVSALQGKKVIDVACGSLHCVACTDSGEVFTWGDNDEGQLGDGTTNAIQR--PRMVAA 236

Query: 384 FLRFAVQLIACGGCHMLVFAT 404
                +  +ACG  H L ++T
Sbjct: 237 LQGKKINRVACGSAHSLAWST 299

 Score = 45.1 bits (105), Expect = 1e-04,   Method: Composition-based stats.
 Identities = 30/93 (32%), Positives = 46/93 (49%), Gaps = 2/93 (2%)
 Frame = +3

Query: 150 GGNNEGQLGLGDTDDRDTFHQIVFFTPADTIKQLSAGANTSAALTEDGKLFMWGDNSEGQ 209
           G  +  +LG G TDD     + V       +  ++ G+    A T+ G++F WGDN EGQ
Sbjct: 9   GKGDYHRLGHG-TDDHVRRPRRVSALQGKKVIDVACGSLHCVACTDSGEVFTWGDNDEGQ 185

Query: 210 IGLEDKSNVCIPHEVTV--GKPISWISCGYYHS 240
           +G    + +  P  V    GK I+ ++CG  HS
Sbjct: 186 LGDGTTNAIQRPRMVAALQGKKINRVACGSAHS 284
>20162
          Length = 1121

 Score = 52.4 bits (124), Expect = 6e-07,   Method: Compositional matrix adjust.
 Identities = 58/236 (24%), Positives = 92/236 (38%), Gaps = 28/236 (11%)
 Frame = +1

Query: 91  NNKLYMFGSNNWGQLGLGSKAAII----KPTCIKALKPEKVKL----------------- 129
           N  LY FG   +GQLG  S         K      + P KV +                 
Sbjct: 133 NGNLYSFGCPEYGQLGHNSDGKYFVTSNKMEYKCEMTPRKVSVFIEKTRDGHVMPITDVD 312

Query: 130 ---AACGRNHTLVSTDTGGVYAAGGNNEGQLGLGDTDDRDTFHQIVFFT-PADTIKQLSA 185
               ACG NHTL+      +++ G    G+LG  +  D      I FF  P     Q+  
Sbjct: 313 IREVACGLNHTLIMDSKKRLFSWGFGGYGRLGHAEPKDELVPRLIKFFDGPGRGGSQIQC 492

Query: 186 GANTSAALTEDGKLFMWGDNS-EGQIGLEDKSNVCIPHEVTVGKPISWISCGYYHSAFVT 244
           G++    + E G L+ WG +   G+  +  K    +  +++ G  +  I C  Y S  + 
Sbjct: 493 GSSFCMTVNEHGALYFWGQSKPTGEATMYPK----LVQDLS-GWKVRSIGC-CYRSIVLC 654

Query: 245 MDGELYTFG-EPENGKLGLPNELLMNHRSPQRVLGIPERVIQ-VACGGGHTVVLTE 298
            D  + ++G  P  G+LG     + +    Q V  +    +  VACG  HT+++  
Sbjct: 655 ADDSVVSWGPSPTYGELGYGENKMKSSTVAQEVKPLDGVYVHDVACGYAHTLMIAR 822

 Score = 35.4 bits (80), Expect = 0.086,   Method: Compositional matrix adjust.
 Identities = 33/127 (25%), Positives = 49/127 (38%)
 Frame = +1

Query: 240 SAFVTMDGELYTFGEPENGKLGLPNELLMNHRSPQRVLGIPERVIQVACGGGHTVVLTEK 299
           S    ++G LY+FG PE G+LG        H S                  G   V + K
Sbjct: 115 STMSDINGNLYSFGCPEYGQLG--------HNSD-----------------GKYFVTSNK 219

Query: 300 VVYAXXXXXXXXXXXXXXXXETSEPKIIERIKDQKICHISCGENHTALMTELGLLYTFGD 359
           + Y                 E +    +  I D  I  ++CG NHT +M     L+++G 
Sbjct: 220 MEYKCEMTPRKVSVFI----EKTRDGHVMPITDVDIREVACGLNHTLIMDSKKRLFSWGF 387

Query: 360 GRHGKLG 366
           G +G+LG
Sbjct: 388 GGYGRLG 408

 Score = 31.6 bits (70), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 37/174 (21%), Positives = 72/174 (41%), Gaps = 7/174 (4%)
 Frame = +1

Query: 78  LSCGDEHTAIVTGNNKLYMFGSNNWGQLGLGSKAAIIKPTCIKALK-PEK-VKLAACGRN 135
           ++CG  HT I+    +L+ +G   +G+LG       + P  IK    P +      CG +
Sbjct: 322 VACGLNHTLIMDSKKRLFSWGFGGYGRLGHAEPKDELVPRLIKFFDGPGRGGSQIQCGSS 501

Query: 136 HTLVSTDTGGVYAAGGNNEGQLGLGDTDDRDTFHQIVFFTPADTIKQLSAGANTSAALTE 195
             +   + G +Y  G +         T +   + ++V       ++ +      S  L  
Sbjct: 502 FCMTVNEHGALYFWGQSKP-------TGEATMYPKLVQDLSGWKVRSIGC-CYRSIVLCA 657

Query: 196 DGKLFMWGDN-SEGQIGL-EDK-SNVCIPHEVTV--GKPISWISCGYYHSAFVT 244
           D  +  WG + + G++G  E+K  +  +  EV    G  +  ++CGY H+  + 
Sbjct: 658 DDSVVSWGPSPTYGELGYGENKMKSSTVAQEVKPLDGVYVHDVACGYAHTLMIA 819
>12101
          Length = 1020

 Score = 52.4 bits (124), Expect = 7e-07,   Method: Compositional matrix adjust.
 Identities = 32/88 (36%), Positives = 46/88 (52%), Gaps = 1/88 (1%)
 Frame = -2

Query: 78  LSCGDEHTAIVTGNNKLYMFGSNNWGQLGLGSKAAII-KPTCIKALKPEKVKLAACGRNH 136
           ++ G  HT I+  N +    G   +G+LGLG    ++ KPT I  L   KV   ACG   
Sbjct: 758 IAGGQHHTLILDNNMRCLAVGRPEYGRLGLGKVTEVVTKPTAITQLNG-KVNYVACGEAC 582

Query: 137 TLVSTDTGGVYAAGGNNEGQLGLGDTDD 164
           +   T+ G +Y+ G  +  QLG+GD DD
Sbjct: 581 SFXITNDGKLYSWGMGSLLQLGVGDGDD 498

 Score = 48.5 bits (114), Expect = 9e-06,   Method: Compositional matrix adjust.
 Identities = 46/162 (28%), Positives = 66/162 (40%), Gaps = 11/162 (6%)
 Frame = -2

Query: 94  LYMFGSNNWGQLGLGSKAAIIKPTCIKALKPEKVKLAACGRNHTLVSTDTGGVYAAGGNN 153
           ++  G NN+ QL    +           +K   VK  A G++HTL+  +     A G   
Sbjct: 860 IWAVGLNNYKQLAHPKETERFLTPVKTEIK--DVKQIAGGQHHTLILDNNMRCLAVGRPE 687

Query: 154 EGQLGLGDTDDRDTFHQIVFFTPADTIKQLSAGANTSAA-------LTEDGKLFMWGDNS 206
            G+LGLG   +          T    I QL+   N  A        +T DGKL+ WG  S
Sbjct: 686 YGRLGLGKVTE--------VVTKPTAITQLNGKVNYVACGEACSFXITNDGKLYSWGMGS 531

Query: 207 EGQIGLEDKSNVCIPHEV----TVGKPISWISCGYYHSAFVT 244
             Q+G+ D  +  +P EV    T  K +     G  HS F+ 
Sbjct: 530 LLQLGVGDGDDEVVPVEVSSKNTQNKKVLLADGGGQHSVFLV 405

 Score = 44.3 bits (103), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 46/173 (26%), Positives = 79/173 (45%), Gaps = 15/173 (8%)
 Frame = -2

Query: 141 TDTGGVYAAGGNNEGQLGLGDTDDRDTFHQIVFFTPADT----IKQLSAGANTSAALTED 196
           + T  ++A G NN  QL      +R       F TP  T    +KQ++ G + +  L  +
Sbjct: 875 SQTQTIWAVGLNNYKQLAHPKETER-------FLTPVKTEIKDVKQIAGGQHHTLILDNN 717

Query: 197 GKLFMWGDNSEGQIGLEDKSNVCI-PHEVT-VGKPISWISCGYYHSAFVTMDGELYTFGE 254
            +    G    G++GL   + V   P  +T +   +++++CG   S  +T DG+LY++G 
Sbjct: 716 MRCLAVGRPEYGRLGLGKVTEVVTKPTAITQLNGKVNYVACGEACSFXITNDGKLYSWGM 537

Query: 255 PENGKLG--------LPNELLMNHRSPQRVLGIPERVIQVACGGG-HTVVLTE 298
               +LG        +P E+   +   ++VL        +A GGG H+V L E
Sbjct: 536 GSLLQLGVGDGDDEVVPVEVSSKNTQNKKVL--------LADGGGQHSVFLVE 402

 Score = 30.8 bits (68), Expect = 2.2,   Method: Compositional matrix adjust.
 Identities = 22/70 (31%), Positives = 36/70 (51%), Gaps = 4/70 (5%)
 Frame = -2

Query: 78  LSCGDEHTAIVTGNNKLYMFGSNNWGQLGLGSKAAIIKPTCI--KALKPEKVKLAACGRN 135
           ++CG+  +  +T + KLY +G  +  QLG+G     + P  +  K  + +KV LA  G  
Sbjct: 602 VACGEACSFXITNDGKLYSWGMGSLLQLGVGDGDDEVVPVEVSSKNTQNKKVLLADGGGQ 423

Query: 136 HT--LVSTDT 143
           H+  LV  D 
Sbjct: 422 HSVFLVEADV 393

 Score = 30.4 bits (67), Expect = 3.0,   Method: Compositional matrix adjust.
 Identities = 31/122 (25%), Positives = 56/122 (45%), Gaps = 2/122 (1%)
 Frame = -2

Query: 283 VIQVACGGGHTVVLTEKV-VYAXXXXXXXXXXXXXXXXETSEPKIIERIKDQKICHISCG 341
           V Q+A G  HT++L   +   A                  ++P  I ++ + K+ +++CG
Sbjct: 767 VKQIAGGQHHTLILDNNMRCLAVGRPEYGRLGLGKVTEVVTKPTAITQL-NGKVNYVACG 591

Query: 342 ENHTALMTELGLLYTFGDGRHGKLGLGMENFTNQFFPT-LCSNFLRFAVQLIACGGCHML 400
           E  +  +T  G LY++G G   +LG+G  +  ++  P  + S   +    L+A GG    
Sbjct: 590 EACSFXITNDGKLYSWGMGSLLQLGVG--DGDDEVVPVEVSSKNTQNKKVLLADGGGQHS 417

Query: 401 VF 402
           VF
Sbjct: 416 VF 411
>39525
          Length = 450

 Score = 36.6 bits (83), Expect = 0.033,   Method: Composition-based stats.
 Identities = 14/37 (37%), Positives = 26/37 (70%), Gaps = 2/37 (5%)
 Frame = -3

Query: 180 IKQLSAGANTS--AALTEDGKLFMWGDNSEGQIGLED 214
           ++ +++G N     A+T++GK++ WG N +GQ+GL D
Sbjct: 160 VRTIASGCNACHCVAITDEGKVYTWGRNEKGQLGLSD 50

 Score = 29.6 bits (65), Expect = 4.6,   Method: Composition-based stats.
 Identities = 12/30 (40%), Positives = 19/30 (63%)
 Frame = -3

Query: 235 CGYYHSAFVTMDGELYTFGEPENGKLGLPN 264
           C   H   +T +G++YT+G  E G+LGL +
Sbjct: 139 CNACHCVAITDEGKVYTWGRNEKGQLGLSD 50
>03352
          Length = 935

 Score = 35.8 bits (81), Expect = 0.062,   Method: Compositional matrix adjust.
 Identities = 33/130 (25%), Positives = 54/130 (41%), Gaps = 16/130 (12%)
 Frame = +2

Query: 45  LVPDTGAVFTFGKTKFAEN---------------IPSK-FWFKNDIPICLSCGDEHTAIV 88
           ++ D G+VF  G  K  E+                P K    +N   + ++C    +A+V
Sbjct: 80  MLADDGSVFFVGLAKRGEDGDSGAAKGRRQPKSVKPKKMIRVENKQVVFVACNSGSSAVV 259

Query: 89  TGNNKLYMFGSNNWGQLGLGSKAAIIKPTCIKALKPEKVKLAACGRNHTLVSTDTGGVYA 148
           T + ++YMFG +        +         +  LK   V   A G+ HT+  T  G ++ 
Sbjct: 260 TKDGEVYMFGKD--------TSHCDHASGHVTDLKDVVVTQVALGKAHTVALTSKGQLFT 415

Query: 149 AGGNNEGQLG 158
            G NN+GQ G
Sbjct: 416 FGINNKGQCG 445

 Score = 35.4 bits (80), Expect = 0.082,   Method: Compositional matrix adjust.
 Identities = 28/100 (28%), Positives = 44/100 (44%)
 Frame = +2

Query: 114 IKPTCIKALKPEKVKLAACGRNHTLVSTDTGGVYAAGGNNEGQLGLGDTDDRDTFHQIVF 173
           +KP  +  ++ ++V   AC    + V T  G VY  G          DT   D     V 
Sbjct: 179 VKPKKMIRVENKQVVFVACNSGSSAVVTKDGEVYMFG---------KDTSHCDHASGHVT 331

Query: 174 FTPADTIKQLSAGANTSAALTEDGKLFMWGDNSEGQIGLE 213
                 + Q++ G   + ALT  G+LF +G N++GQ G +
Sbjct: 332 DLKDVVVTQVALGKAHTVALTSKGQLFTFGINNKGQCGRD 451

 Score = 31.2 bits (69), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 35/154 (22%), Positives = 63/154 (40%), Gaps = 11/154 (7%)
 Frame = +2

Query: 224 VTVGKPISWISCGY--YHSAFVTMDGELYTFGEPENGKLGLPNELLMNHRSPQRVLGIPE 281
           +T    I  ++ G+   H+  +  DG ++  G  + G+ G  +      R P+ V   P+
Sbjct: 20  ITKSPKIQQVATGHEGAHALMLADDGSVFFVGLAKRGEDG-DSGAAKGRRQPKSVK--PK 190

Query: 282 RVIQV--------ACGGGHTVVLTEK-VVYAXXXXXXXXXXXXXXXXETSEPKIIERIKD 332
           ++I+V        AC  G + V+T+   VY                        +  +KD
Sbjct: 191 KMIRVENKQVVFVACNSGSSAVVTKDGEVYMFGKDTSHCDHASGH---------VTDLKD 343

Query: 333 QKICHISCGENHTALMTELGLLYTFGDGRHGKLG 366
             +  ++ G+ HT  +T  G L+TFG    G+ G
Sbjct: 344 VVVTQVALGKAHTVALTSKGQLFTFGINNKGQCG 445
>04349
          Length = 1161

 Score = 31.6 bits (70), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 12/26 (46%), Positives = 16/26 (61%)
 Frame = +3

Query: 382 SNFLRFAVQLIACGGCHMLVFATPRL 407
           S  +R AVQL  CG CH  V+A  ++
Sbjct: 195 SKSMRVAVQLEKCGACHKTVYAMEKI 272
>03731
          Length = 728

 Score = 30.4 bits (67), Expect = 2.9,   Method: Composition-based stats.
 Identities = 12/26 (46%), Positives = 16/26 (61%)
 Frame = +2

Query: 382 SNFLRFAVQLIACGGCHMLVFATPRL 407
           S  +R AVQL  CG CH  V+A  ++
Sbjct: 551 SKSMRVAVQLEKCGACHKTVYAMEKI 628
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|51093840|ref|NP_660121.2| eukaryotic translation
initiation factor 3 subunit 6 interacting protein [Mus musculus]
         (564 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

37635                                                                 297   9e-81
>37635
          Length = 2610

 Score =  297 bits (760), Expect = 9e-81,   Method: Compositional matrix adjust.
 Identities = 137/207 (66%), Positives = 169/207 (81%)
 Frame = -2

Query: 357  YEMINKQNEQMHALLAIALTMYPMRIDESIHLQLREKYGDKMLRMQKGDPQVYEELFSYA 416
            Y+ INK N++M+ LLAI L ++PMRIDES+H  LREKY DK LRMQK +   +E+ F++A
Sbjct: 2588 YDQINKNNDKMYTLLAICLVLHPMRIDESVHSHLREKYADKQLRMQKCELGEFEQCFAFA 2409

Query: 417  CPKFLSPVVPNYDNVHPNYHKEPFLQQLKVFSDEVQQQAQLSTIRSFLKLYTTMPVAKLA 476
            CPKFLSPV PNYD +   +HKEPF  QL+VF DEV+QQ Q+ TIRS+LKLYTT+P++KLA
Sbjct: 2408 CPKFLSPVPPNYDLMTDTHHKEPFKLQLRVFLDEVKQQIQIPTIRSYLKLYTTLPISKLA 2229

Query: 477  GFLDLTEQEFRIQLLVFKHKMKNLVWTSGISALDGEFQSASEVDFYIDKDMIHIADTKVA 536
             F+D  E+  R QL+ FKHKMKNLVWT G S L+GEFQSASEVDFY+D +MIHIADTKVA
Sbjct: 2228 IFMDEPEERLRTQLMCFKHKMKNLVWTKGTSCLEGEFQSASEVDFYVDGNMIHIADTKVA 2049

Query: 537  RRYGDFFIRQIHKFEELNRTLKKMGQR 563
            RRYGDFFIRQIHKFEE+ R L+++G +
Sbjct: 2048 RRYGDFFIRQIHKFEEITRNLQQIGTK 1968
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|184186088|ref|NP_598887.3| intraflagellar transport
140 [Mus musculus]
         (1464 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

20391                                                                 297   2e-80
02948                                                                  40   0.008
27681                                                                  32   1.6  
38554                                                                  31   3.4  
34005                                                                  30   5.2  
>20391
          Length = 582

 Score =  297 bits (760), Expect = 2e-80,   Method: Compositional matrix adjust.
 Identities = 135/191 (70%), Positives = 165/191 (86%)
 Frame = -1

Query: 752 PQMVAKRPLRDFVGLEDCDKSTRDAMLNFSFFVTIGDMDEAFKSIKLIKSEAVWENMARM 811
           P++V+++ +RDFVGLE  DK TRDAM+NFSF +T G+MDEAFKSIKLIKSE+VWENMA+M
Sbjct: 573 PKLVSRKIMRDFVGLESSDKPTRDAMMNFSFHLTTGNMDEAFKSIKLIKSESVWENMAKM 394

Query: 812 CVKTQRLDVAKVCLGNMGHARGARALREAEQEPELEARVAMLAIQLGMLEEAEQLYKKCK 871
           CVK++RLDVA VCLGNMGHARGA+ALREA +EPEL+ARVA+LAIQLG+ E+ E+L + CK
Sbjct: 393 CVKSRRLDVASVCLGNMGHARGAKALREALKEPELDARVAVLAIQLGLHEDGERLLRNCK 214

Query: 872 RYDLLNKFYQASDQWQKAVEVAELHDRVHLRTTYYNYAKHLEASADCGQALSYYEKSDTH 931
           RYDLLN+FYQ S QW KA+E AE++DR+HLR+TYYNYA HLE   D   A+  YEKS+TH
Sbjct: 213 RYDLLNEFYQNSGQWNKALETAEMYDRIHLRSTYYNYAHHLEERGDTNGAIPNYEKSETH 34

Query: 932 RFEVPRMLSED 942
           RFEVPRML +D
Sbjct: 33  RFEVPRMLVDD 1
>02948
          Length = 1207

 Score = 39.7 bits (91), Expect = 0.008,   Method: Composition-based stats.
 Identities = 21/71 (29%), Positives = 39/71 (54%), Gaps = 2/71 (2%)
 Frame = -2

Query: 65  TSLCWHPTRLILAIGWETGEVIMF--NKQDKEQHTVPLPHTTDIAILSWSTSGSCLVSGD 122
           T +  HPT + +A G  +G++  +    QDK   +V   H+  +  L+++  GSCL+SG 
Sbjct: 744 TCVSCHPTDVCIATGHASGKITFWWNFDQDKTVLSVSHWHSLPVTCLAFTPEGSCLLSGG 565

Query: 123 KLGVLLLWRLD 133
               L+ W+++
Sbjct: 564 HECTLVRWQMN 532
>27681
          Length = 465

 Score = 32.3 bits (72), Expect = 1.6,   Method: Composition-based stats.
 Identities = 23/79 (29%), Positives = 33/79 (41%), Gaps = 14/79 (17%)
 Frame = +2

Query: 69  WHPTRLILAIG--------WE-TGEVIMFNKQDKEQHTV-----PLPHTTDIAILSWSTS 114
           W+PT  +LA G        W  T E      Q   +H +      +P   D+  L W++ 
Sbjct: 17  WNPTNDLLASGSGDSTARIWNMTSETPNNANQLVLRHCIQKGGTEVPSNKDVTSLDWNSE 196

Query: 115 GSCLVSGDKLGVLLLWRLD 133
           G+ L +G   G   LWR D
Sbjct: 197 GTLLATGSYDGYARLWRTD 253
>38554
          Length = 703

 Score = 31.2 bits (69), Expect = 3.4,   Method: Compositional matrix adjust.
 Identities = 28/119 (23%), Positives = 56/119 (47%), Gaps = 1/119 (0%)
 Frame = -3

Query: 1234 KIVFFAGVSRQK-EIYIMAANYLQSLDWRKEPEIMKSIISFYTKGRALDLLAGFYDACAQ 1292
            K+ +F   +R+  E++     +   ++W K      SI+    KGRAL     FY    +
Sbjct: 698  KLPYFRRKNRRH*ELHF*VEKHAAVMEWPKS--SWGSILPSLLKGRALT----FYH---E 546

Query: 1293 VEIDEYQNYDKAHGALTEAYKCLSKAKTKNPLDQETKLAQLQSKMTLVKRFIQARRTYT 1351
            + +++ QNYD  H  L ++++C     T+     + + A+ ++   +   F + RR +T
Sbjct: 545  LPVEQSQNYDILHKHLLKSFRC-----TEEGFRLQFRSAKPETGENMPTFFSRLRRYFT 384
>34005
          Length = 456

 Score = 30.4 bits (67), Expect = 5.2,   Method: Composition-based stats.
 Identities = 31/115 (26%), Positives = 46/115 (40%), Gaps = 5/115 (4%)
 Frame = +1

Query: 12  PDTPSSPSHITWHPTHPFLAVASISPSSGGNVDIYLEQ-GEPVPDTHIERSFQAT--SLC 68
           P TP     ++W P   FLA    S S+  +V+I+    G  VP  H   S QA   ++ 
Sbjct: 103 PLTPQEVCGLSWSPDATFLA----SGSNDNSVNIWDSTLGMDVPPLHTLTSHQAAVKAVA 270

Query: 69  WHP--TRLILAIGWETGEVIMFNKQDKEQHTVPLPHTTDIAILSWSTSGSCLVSG 121
           W P  TR++   G      I F   +       +   + +  + W      LVSG
Sbjct: 271 WCPWQTRMLATGGGTNDRHIRFWNTNTGACVKAVDTQSQVCSVLWCKEHRELVSG 435
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|9790077|ref|NP_062801.1| glycogen synthase kinase 3
beta [Mus musculus]
         (420 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

32359                                                                 244   2e-80
05084                                                                 217   7e-57
01707                                                                 155   2e-38
01060                                                                 138   5e-33
14126                                                                 136   1e-32
29581                                                                 118   5e-27
01756                                                                 117   6e-27
04591                                                                 103   1e-22
28638                                                                  75   4e-22
04138                                                                  99   3e-21
13592                                                                  93   2e-19
32000                                                                  89   3e-18
03508                                                                  89   3e-18
00300                                                                  85   4e-17
23319                                                                  79   4e-15
18921                                                                  77   1e-14
12721                                                                  77   2e-14
03240                                                                  75   5e-14
09606                                                                  73   2e-13
15910                                                                  71   9e-13
13066                                                                  70   1e-12
12453                                                                  68   6e-12
18484                                                                  68   6e-12
06405                                                                  68   7e-12
30755                                                                  67   1e-11
19301                                                                  66   3e-11
01966                                                                  65   5e-11
09007                                                                  64   9e-11
26560                                                                  64   1e-10
14116                                                                  62   3e-10
31885                                                                  62   4e-10
12786                                                                  62   6e-10
01718                                                                  61   1e-09
18287                                                                  60   1e-09
01392                                                                  60   2e-09
13212                                                                  59   3e-09
14420                                                                  59   5e-09
03294                                                                  57   9e-09
31489                                                                  57   1e-08
27546                                                                  56   3e-08
17975                                                                  55   7e-08
27405                                                                  54   2e-07
18401                                                                  54   2e-07
26711                                                                  52   4e-07
07940                                                                  52   4e-07
11185                                                                  52   7e-07
19761                                                                  51   7e-07
19094                                                                  51   8e-07
21433                                                                  50   2e-06
14477                                                                  49   3e-06
00715                                                                  49   5e-06
04852                                                                  47   1e-05
28157                                                                  47   2e-05
21808                                                                  47   2e-05
11404                                                                  45   5e-05
21079                                                                  45   7e-05
12672                                                                  44   1e-04
16708                                                                  42   3e-04
07291                                                                  40   0.001
00638                                                                  40   0.002
36481                                                                  40   0.002
16003                                                                  39   0.003
26009                                                                  38   0.006
25019                                                                  38   0.010
21800                                                                  38   0.010
01106                                                                  38   0.010
29360                                                                  36   0.030
13078                                                                  35   0.039
02638                                                                  35   0.060
00486                                                                  34   0.12 
20152                                                                  33   0.15 
37602                                                                  33   0.20 
18481                                                                  32   0.44 
35032                                                                  32   0.65 
38560                                                                  31   1.0  
19248                                                                  30   1.6  
32357                                                                  30   1.6  
24241                                                                  30   1.8  
19149                                                                  28   5.1  
32957                                                                  28   6.5  
26052                                                                  28   7.5  
>32359
          Length = 928

 Score =  244 bits (624), Expect(3) = 2e-80,   Method: Compositional matrix adjust.
 Identities = 113/131 (86%), Positives = 126/131 (96%)
 Frame = -1

Query: 44  PGQGPDRPQEVSYTDTKVIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKNRELQIMRK 103
            GQGPDRPQEVSYTD KVIGNGSFGVVYQAKL D+ ELVAIKKVLQDKRFKNRELQIMRK
Sbjct: 460 SGQGPDRPQEVSYTDAKVIGNGSFGVVYQAKLVDTSELVAIKKVLQDKRFKNRELQIMRK 281

Query: 104 LDHCNIVRLRYFFYSSGEKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMY 163
           L+H NIV+L++FFYSSGEKKDEV+LNLVL+YVPETVYRVARHYS++KQT+P++Y+KLYMY
Sbjct: 280 LEHQNIVKLKFFFYSSGEKKDEVFLNLVLEYVPETVYRVARHYSKSKQTIPILYIKLYMY 101

Query: 164 QLFRSLAYIHS 174
           QLFRSLAYIHS
Sbjct: 100 QLFRSLAYIHS 68

 Score = 49.7 bits (117), Expect(3) = 2e-80,   Method: Compositional matrix adjust.
 Identities = 28/43 (65%), Positives = 31/43 (72%)
 Frame = -2

Query: 1   MSGRPRTTSFAESCKPVQQPSAFGSMKVSRDKDGSKVTTVVAT 43
           MSGRPRTTSFAE  KP Q  + FG M+    KDG KVTTV+AT
Sbjct: 582 MSGRPRTTSFAEGGKPGQN-APFGGMRTI-SKDGGKVTTVLAT 460

 Score = 44.3 bits (103), Expect(3) = 2e-80,   Method: Compositional matrix adjust.
 Identities = 18/21 (85%), Positives = 20/21 (95%)
 Frame = -3

Query: 176 GICHRDIKPQNLLLDPDTAVL 196
           G+CHRDIKPQNLLLDP+T VL
Sbjct: 65  GVCHRDIKPQNLLLDPETGVL 3
>05084
          Length = 1324

 Score =  217 bits (553), Expect = 7e-57,   Method: Compositional matrix adjust.
 Identities = 102/127 (80%), Positives = 111/127 (87%)
 Frame = +2

Query: 257 FPGDSGVDQLVEIIKVLGTPTREQIREMNPNYTEFKFPQIKAHPWTKVFRPRTPPEAIAL 316
            PGDSGVDQLVEIIKVLGTPTREQIREMNPNY+EFKFPQIKAHPWTKVFRPRTPPEAI L
Sbjct: 2   LPGDSGVDQLVEIIKVLGTPTREQIREMNPNYSEFKFPQIKAHPWTKVFRPRTPPEAIQL 181

Query: 317 CSRLLEYTPTARLTPLEACAHSFFDELRDPNVKLPNGRDTPALFNFTTQELSSNPPLATI 376
            SRLLEYTP+AR+ P+EACAH+FFDELRDP  +LPNGR+ P LF+FT  EL+  P L   
Sbjct: 182 VSRLLEYTPSARIQPMEACAHAFFDELRDPASRLPNGRELPPLFSFTQMELAIAPQLNAS 361

Query: 377 LIPPHAR 383
           LIPPHAR
Sbjct: 362 LIPPHAR 382
>01707
          Length = 757

 Score =  155 bits (393), Expect = 2e-38,   Method: Compositional matrix adjust.
 Identities = 91/227 (40%), Positives = 131/227 (57%), Gaps = 7/227 (3%)
 Frame = +1

Query: 55  SYTDTKVIGNGSFGVVYQAKLCDSGELVAIKKVLQD------KRFKNRELQIMRKLDHCN 108
            Y     IG GS+GVV++ +  ++ +LVAIKK ++       K+   RE++++++L H N
Sbjct: 67  KYEKIGKIGEGSYGVVFKCRNKETSQLVAIKKFVESEDDPLIKKIAMREIRMLKQLKHPN 246

Query: 109 IVRLRYFFYSSGEKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFRS 168
           +VRL   F      + +  L+LV DYV  T+      Y R    LP   VK  +YQ   +
Sbjct: 247 LVRLIEVF------RRKKRLHLVFDYVDHTLLNELDRYPRG---LPEPMVKRIIYQTLLA 399

Query: 169 LAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVR-GEPNVSYICSRYYRAPEL 227
           + + H +   HRD+KP+N+L+     V KLCDFG A+ L   G+    Y+ +R+YRAPEL
Sbjct: 400 VNFCHQYNTIHRDVKPENILITRQGQV-KLCDFGFARILTGPGDEYTDYVATRWYRAPEL 576

Query: 228 IFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLG 274
           + G T Y   +DVW+ GCV AELL GQ ++PG S VDQL  I K LG
Sbjct: 577 LVGDTQYGPPVDVWAIGCVFAELLTGQALWPGRSDVDQLHLIRKTLG 717
>01060
          Length = 1800

 Score =  138 bits (347), Expect = 5e-33,   Method: Compositional matrix adjust.
 Identities = 96/307 (31%), Positives = 154/307 (50%), Gaps = 23/307 (7%)
 Frame = +1

Query: 57  TDTKVIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKN----------RELQIMRKLDH 106
           TD + IG G++GVVY+ +   +G  +A+KK+    R +           RE+ ++R+L H
Sbjct: 82  TDFQKIGEGTYGVVYKCRHRATGRKLAMKKI----RLRGSEDGVPSSAIREIAMLRELRH 249

Query: 107 CNIVRL--------RYFFYSSGEKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYV 158
            NIV L        R F        D   L + +D  PE V    R             V
Sbjct: 250 TNIVCLEDVIMEDERLFLVFEFLSMD---LKMYIDKFPEGVVLDRR------------LV 384

Query: 159 KLYMYQLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSY-- 216
           K Y++Q+   + + H   I HRD+KPQNLL++  T  +K+ DFG A+      P  +Y  
Sbjct: 385 KSYVFQIVTGIXFCHQRRIVHRDLKPQNLLIN-HTGAIKIADFGMARTF--ALPVRAYTH 555

Query: 217 -ICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGT 275
            + + +YRAPE++ GA+ Y++ +DVWS G + A++L+  PIF GDS +DQL +I +++GT
Sbjct: 556 EVVTLWYRAPEILMGASKYSTPVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIFRIIGT 735

Query: 276 PTREQIREMN--PNYTEFKFPQIKAHPWTKVFRPRTPPEAIALCSRLLEYTPTARLTPLE 333
           PT +   E +  P +    FP  K    ++          + L  R L+  P  R++  +
Sbjct: 736 PTEQTWPEFHKLPAFNGM-FPLWKEGKLSETLTD-LDSLGLDLIERTLKCDPAQRISCKK 909

Query: 334 ACAHSFF 340
              H++F
Sbjct: 910 MLQHAYF 930
>14126
          Length = 1265

 Score =  136 bits (343), Expect = 1e-32,   Method: Compositional matrix adjust.
 Identities = 107/351 (30%), Positives = 175/351 (49%), Gaps = 17/351 (4%)
 Frame = +3

Query: 12  ESCKPVQQPSAFGSMKVSRDKDGSKVTTVVATPGQGPDRPQEVSYTDTKVIGNGSFGVVY 71
           E   P   P A  SMK +    G    +  A          E  Y +  VIGNG++G VY
Sbjct: 66  EESSPKTSP-AVRSMKTAISPKGRDGQSESAAKMSRRRDSTEQKYEEVAVIGNGAYGTVY 242

Query: 72  QAK-LCDSGELVAIKKVLQDKRFKN----------RELQIMRKLD---HCNIVRLRYFFY 117
           +A+ L + GE VA+K++    R  N          RE+ ++++L+   H N+VRL    +
Sbjct: 243 KARDLRNQGEFVAMKRI----RLNNTEEGMPMMAIREISMLKQLEQYEHPNVVRLLDVSH 410

Query: 118 SSGEKKDEVYLNLVLDYVPETVYRVARHYSRAKQ-TLPVIYVKLYMYQLFRSLAYIHSFG 176
           ++   + E+ LNLV +Y+    + +A + ++     L    +K  M QL   + ++HS  
Sbjct: 411 NTITDR-EIRLNLVFEYIE---HDLATYLAKCPSPGLGPDRIKDLMLQLLNGVDFLHSNR 578

Query: 177 ICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYTS 236
           I HRD+KPQNLL+  D   LKL DFG A+         + + + +YR+PE++  A +Y +
Sbjct: 579 IVHRDLKPQNLLISKD-GRLKLADFGLARIYSFHMALTTVVVTLWYRSPEVLMQA-EYGT 752

Query: 237 SIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIRE-MNPNYTEFK-FP 294
           S+D+WS GC+ AEL   + +F G S  DQL +I +V+G P      E ++ +   F+  P
Sbjct: 753 SVDIWSCGCIFAELFTRRALFKGSSEFDQLKKIFEVIGLPPAGDWPEGVSVHRNSFRPTP 932

Query: 295 QIKAHPWTKVFRPRTPPEAIALCSRLLEYTPTARLTPLEACAHSFFDELRD 345
            +      +   P   P+A  L  ++L +    R++  E+  H +   LRD
Sbjct: 933 PVP----LQTLVPEMDPQAKDLMEKMLVFKSGRRISSRESLLHPY---LRD 1064
>29581
          Length = 1278

 Score =  118 bits (295), Expect = 5e-27,   Method: Compositional matrix adjust.
 Identities = 80/253 (31%), Positives = 133/253 (52%), Gaps = 10/253 (3%)
 Frame = -2

Query: 100  IMRKLDHCNIVRLRYFFYSSGEKKDEVYLNLVLDYVPETVYRVARH----YSRAKQTLPV 155
             +  L H NIV+L+      G+  D ++L  V++Y  + +  +  +    +S ++     
Sbjct: 1196 FLLNLRHQNIVQLQEVVV--GKSLDSLFL--VMEYCEQDLASLLDNMPAPFSESQ----- 1044

Query: 156  IYVKLYMYQLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGE-PNV 214
              VK  + QL + L Y+H   I HRD+K  NLL+  D   +K+ DFG A+   + + P  
Sbjct: 1043 --VKCIVLQLLKGLRYLHEAFIIHRDLKVSNLLMT-DKGCVKIADFGLARNYGKPQKPMT 873

Query: 215  SYICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLG 274
              + + +YRAPEL+FG+  ++++ID+WSAGC+L ELL  +P+ PG S + Q+  I+++LG
Sbjct: 872  PKVVTLWYRAPELLFGSKTHSTAIDMWSAGCILGELLGHKPLMPGRSDLQQIELIMELLG 693

Query: 275  TPTREQIREMNPNYTEF-KFPQ--IKAHPWTKVFR--PRTPPEAIALCSRLLEYTPTARL 329
            TP       + P +++   F Q  +K  P+  +    P      I L + L  Y P  R 
Sbjct: 692  TPN----DTIWPGFSQLPAFEQFTLKKQPYNNLRHTFPWLSESGIRLLNGLFMYHPQKRA 525

Query: 330  TPLEACAHSFFDE 342
            T  +   HS+F E
Sbjct: 524  TAEDCLEHSYFKE 486
>01756
          Length = 1858

 Score =  117 bits (294), Expect = 6e-27,   Method: Compositional matrix adjust.
 Identities = 76/240 (31%), Positives = 124/240 (51%), Gaps = 12/240 (5%)
 Frame = -3

Query: 52   QEVSYTDTKVIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKN------RELQIMRKLD 105
            ++  Y     IG G+FG V++A+   + ++VA+KKVL D   +       RE++I++ L+
Sbjct: 1748 EDAKYEKLAKIGQGTFGEVFKARCKKTKQVVAMKKVLMDNEKEGFPITALREIKILQLLN 1569

Query: 106  HCNIVRLRYFFYSSGEKKD--EVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMY 163
            H N+V L     +     +  +    LV ++     + +A   S       +  +K  M 
Sbjct: 1568 HENVVDLIEICSTKATSANRYKSMFYLVFEFCE---HDLAGLLSNMSVVFNLPEIKEVMK 1398

Query: 164  QLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRG--EPN--VSYICS 219
            QL   L YIH   I HRD+K  N+L+     VLKL DFG A+       +PN   + + +
Sbjct: 1397 QLMNGLYYIHRNKILHRDMKAANILITKQ-GVLKLADFGLARAFSVNLRQPNRYTNRVVT 1221

Query: 220  RYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTRE 279
             +YR PEL+ G  +Y+++ID W AGC++AE+    PI  G +  +QL  I ++ G+ T E
Sbjct: 1220 LWYRPPELLLGDRNYSTAIDQWGAGCIMAEMWTRNPIMQGTTEQNQLTLITQLCGSITPE 1041
>04591
          Length = 1117

 Score =  103 bits (258), Expect = 1e-22,   Method: Compositional matrix adjust.
 Identities = 75/252 (29%), Positives = 118/252 (46%), Gaps = 7/252 (2%)
 Frame = -2

Query: 96   RELQIMRKLDHCNIVRLRYFFYSSG----EKKDEVYLNLVLDYVPETVYRVARHYSRAKQ 151
            RE++I+++L+H N+V+L+   ++        K   YL  + +Y     Y +A   +  + 
Sbjct: 1074 REIKILQQLEHENVVQLQEICHTQAGPYNRYKSTFYL--IFEYCD---YDLAGLLNNLRV 910

Query: 152  TLPVIYVKLYMYQLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGE 211
               +   K  M QL   L YIH+  I HRDIK  N+LL  D  VLKL DFG ++  V+ +
Sbjct: 909  KFSLADKKNLMSQLLNGLFYIHTKQILHRDIKAANILLTRD-GVLKLADFGLSRPWVKSK 733

Query: 212  PNVSYICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIK 271
               + + + +YR PEL+ G  +Y   ID+W  GC++AE+   +P+  G S   QL  I  
Sbjct: 732  RLTNRVVTLWYRPPELLLGEREYGPEIDMWGVGCIMAEMWSRKPLMQGRSEQHQLSLITD 553

Query: 272  VLGTPTREQIREMN--PNYTEFKFPQIKAHPWT-KVFRPRTPPEAIALCSRLLEYTPTAR 328
            + G+   E    +     Y +   PQ K      ++       E   L    L   P  R
Sbjct: 552  LCGSLNAEVWPGVTKLELYGKLDLPQGKPRKVKERMLDLLKNKEGAELIDIFLRLDPGQR 373

Query: 329  LTPLEACAHSFF 340
            +    A +H FF
Sbjct: 372  MNCDNALSHDFF 337
>28638
          Length = 1458

 Score = 75.5 bits (184), Expect(3) = 4e-22,   Method: Compositional matrix adjust.
 Identities = 45/113 (39%), Positives = 70/113 (61%), Gaps = 6/113 (5%)
 Frame = -1

Query: 149 AKQTLPVIYVKL---YMYQLFRSLAYIHS--FGICHRDIKPQNLLL-DPDTAVLKLCDFG 202
           A QTL  + + L   +  QL  +L ++ +    I H D+KP+N+LL +P  + +K+ DFG
Sbjct: 867 ATQTLEGVSLNLTRKFAQQLCTALLFLATPEMNIIHCDLKPENILLCNPKRSAIKIVDFG 688

Query: 203 SAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQP 255
           S+ QL  G+    YI SR+YR+PE++ G   Y  +ID+WS GC+L E+  G+P
Sbjct: 687 SSCQL--GQRIYQYIQSRFYRSPEVLLGV-PYDLAIDMWSLGCILVEMHTGEP 538

 Score = 34.3 bits (77), Expect(3) = 4e-22,   Method: Compositional matrix adjust.
 Identities = 32/129 (24%), Positives = 53/129 (41%), Gaps = 36/129 (27%)
 Frame = -2

Query: 253 GQPIFPGDSGVDQLVEIIKVLGTPTREQIREMN---------PNYT----------EFKF 293
           G P+F G +  DQ+++I++VLG P R  + +           P+ T          ++K 
Sbjct: 545 GNPLFAGSNEFDQMMKIVEVLGVPPRHILDQAQKTRKYFDLLPDGTYAPKKPRDNKKYKS 366

Query: 294 PQI----------KAHPWTKVFRPRTPPEAIA-------LCSRLLEYTPTARLTPLEACA 336
           P            K  P  +  R   P   +A       L  R+L++ P  R++P  A  
Sbjct: 365 PSSRKLHEVLGAEKGGPGGR--RMGEPGHTVADYLKFKDLILRMLDFDPKTRISPYYALQ 192

Query: 337 HSFFDELRD 345
           H+FF +  D
Sbjct: 191 HNFFRKTSD 165

 Score = 32.7 bits (73), Expect(3) = 4e-22,   Method: Compositional matrix adjust.
 Identities = 32/99 (32%), Positives = 47/99 (47%), Gaps = 10/99 (10%)
 Frame = -3

Query: 56   YTDTKVIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKNRE------LQIMRKLDHCN- 108
            Y    +IG GSFG V +A      E VAIK +   K F N+       L++M + D  N 
Sbjct: 1141 YEIDSLIGKGSFGQVVKAYDHGDQEQVAIKIIKNKKPFLNQAQIEVKLLELMNRHDADNX 962

Query: 109  --IVRL-RYFFYSSGEKKDEVYLNLVLDYVPETVYRVAR 144
              IVRL R+F + +       +L LV + +   +Y + R
Sbjct: 961  YYIVRLKRHFMFRN-------HLCLVFELLSYNLYDLLR 866
>04138
          Length = 800

 Score = 99.0 bits (245), Expect = 3e-21,   Method: Compositional matrix adjust.
 Identities = 65/185 (35%), Positives = 96/185 (51%), Gaps = 13/185 (7%)
 Frame = +1

Query: 169 LAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRG--EPN--VSYICSRYYRA 224
           L YIH   I HRD+K  N+L+     VLKL DFG A+       +PN   + + + +YR 
Sbjct: 52  LYYIHRNKILHRDMKAANILITKQ-GVLKLADFGLARAFSVNLRQPNRYTNRVVTLWYRP 228

Query: 225 PELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREM 284
           PEL+ G  +Y+++ID W AGC++AE+    PI  G +  +QL  I ++ G+ T     E+
Sbjct: 229 PELLLGDRNYSTAIDQWGAGCIMAEMWTRNPIMQGTTEQNQLTLITQLCGSIT----PEV 396

Query: 285 NPNYTEFK-FPQIK---AHPWTKVFRPR-----TPPEAIALCSRLLEYTPTARLTPLEAC 335
            P  T+   + QIK   A     + R R       P  + L  RLL+  P+ R++  EA 
Sbjct: 397 WPGVTQLSMYHQIKGALAAGRKNIIRDRFARILKDPYGLDLFERLLKMDPSQRISADEAL 576

Query: 336 AHSFF 340
            H FF
Sbjct: 577 NHDFF 591
>13592
          Length = 980

 Score = 92.8 bits (229), Expect = 2e-19,   Method: Compositional matrix adjust.
 Identities = 66/207 (31%), Positives = 106/207 (51%), Gaps = 14/207 (6%)
 Frame = +2

Query: 62  IGNGSFGVVYQAKLCDSGELVAIKKVL----QDKRFKN--RELQIMRKLDHCNIVRLRYF 115
           IG G FG VY A   ++GEL+A+K++     + +  KN   EL+I+  + H N+VR  Y+
Sbjct: 8   IGQGRFGKVYTAVNNNTGELMAMKEIAIQPGETRALKNVAEELKILEGIKHKNLVR--YY 181

Query: 116 FYSSGEKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFRSLAYIHSF 175
                 ++  +++ L  +   E++  +          LP    + +  QL   +A +H  
Sbjct: 182 GIEVHREELLIFMELCSEGTLESLVELT-------GGLPEALSRRFTAQLLSGVAELHKH 340

Query: 176 GICHRDIKPQNLLLDPDTAVLKLCDFGSAKQL-----VRGEPNVSYICSRYYRAPELIFG 230
           GI HRDIK  N+ L   +  LKL DFGSA ++     V GE    Y+ ++ Y APE +F 
Sbjct: 341 GIVHRDIKTANIFLVDGSNSLKLGDFGSAVKIQAHTTVPGELQ-GYVGTQAYMAPE-VFT 514

Query: 231 ATD---YTSSIDVWSAGCVLAELLLGQ 254
            T+   +    D+WS GCV+ E+  G+
Sbjct: 515 KTNSDGHGRLADIWSVGCVVVEMASGK 595
>32000
          Length = 644

 Score = 89.4 bits (220), Expect = 3e-18,   Method: Compositional matrix adjust.
 Identities = 49/161 (30%), Positives = 87/161 (54%), Gaps = 9/161 (5%)
 Frame = -1

Query: 193 TAVLKLCDFGSAKQLVRGEPNVSY---ICSRYYRAPELIFGATDYTSSIDVWSAGCVLAE 249
           TA +K+ DFG A+  V G P  +Y   + + +YRAPE++ G   Y+  +D+WS GC+  E
Sbjct: 581 TAKMKIADFGLAR--VFGLPVRTYTHEVITLWYRAPEILLGCRFYSVPVDIWSLGCIFVE 408

Query: 250 LLLGQPIFPGDSGVDQLVEIIKVLGTPTRE------QIREMNPNYTEFKFPQIKAHPWTK 303
           ++  + +FPGDS +DQL  I + LGTP  +      ++ +  P + ++    ++    T 
Sbjct: 407 MMTRRALFPGDSEIDQLYRIFRTLGTPDEKVWPGVSKLPDYKPTFPKWPLKNLE----TV 240

Query: 304 VFRPRTPPEAIALCSRLLEYTPTARLTPLEACAHSFFDELR 344
           V   +     + L  R+L Y P  R++   A  H +F++++
Sbjct: 239 VSLSKV---GLDLLKRMLTYNPNRRISARSAMRHPYFNDMK 126
>03508
          Length = 1463

 Score = 89.0 bits (219), Expect = 3e-18,   Method: Compositional matrix adjust.
 Identities = 42/115 (36%), Positives = 70/115 (60%), Gaps = 2/115 (1%)
 Frame = +1

Query: 146 YSRAKQTLPVIYVKLYMYQLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAK 205
           + +  QT     ++ Y+Y+L ++L + HS GI HRD+KP N+++D +   L+L D+G A+
Sbjct: 841 FKQLYQTFTDYDIRFYLYELMKALDFCHSMGIMHRDVKPHNVMIDHENKKLRLIDWGLAE 1020

Query: 206 QLVRG-EPNVSYICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLL-GQPIFP 258
               G E NV  + SRY++ PEL+     Y  S+D+WS GC+ A ++   +P+ P
Sbjct: 1021FYHPGMEYNVR-VASRYFKGPELLLDYQMYDYSLDMWSLGCMFASMIFRKEPLLP 1182

 Score = 44.7 bits (104), Expect = 7e-05,   Method: Compositional matrix adjust.
 Identities = 35/111 (31%), Positives = 48/111 (43%), Gaps = 10/111 (9%)
 Frame = +2

Query: 240  VWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTP------TREQIREMNPNYTEFKF 293
            VW+A C+ A      P F G    DQLV I KVLGT        + QI +++P + +   
Sbjct: 1130 VWAA-CLPA*SSGKSPFFHGHDNYDQLVRIAKVLGTDDLYGYIEKYQI-DLDPRFNDI-L 1300

Query: 294  PQIKAHPWTKVFRPRT----PPEAIALCSRLLEYTPTARLTPLEACAHSFF 340
             +     W +           PEA+    +LL Y    RLT  EA  H +F
Sbjct: 1301 GRHSRKRWERFVHSENQHLISPEALDFLDKLLRYDHNERLTAREAMDHPYF 1453
>00300
          Length = 2318

 Score = 85.1 bits (209), Expect = 4e-17,   Method: Compositional matrix adjust.
 Identities = 72/242 (29%), Positives = 116/242 (47%), Gaps = 19/242 (7%)
 Frame = -1

Query: 32   KDGSKVTTVVATPGQGPD-----RPQEVSYTDTKVIGNGSFGVVYQAKLCDSGELVAIKK 86
            ++ S++  V A P + PD     R     +     IG G FG VY A    +GEL+A+K+
Sbjct: 1736 QEKSRIGRVAAKPRE-PDYRINVRRVNFRWQRGNKIGEGQFGKVYTAVNMSTGELMALKE 1560

Query: 87   V------LQDKRFKNRELQIMRKLDHCNIVRLRYFFYSSGEKKDEVYLNLVLDYVPETVY 140
            +      LQ  R    E++I   + H N+V+    +Y     KDE+ +   ++Y      
Sbjct: 1559 MKFQPNDLQQLREMCDEIKIFEGIQHENLVK----YYGVEVHKDEMLM--FMEYCDTGTI 1398

Query: 141  RVARHYSRAKQTLPVIYVKLYMYQLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCD 200
              A     AK  LP   ++ Y  ++  ++ ++H   I HRDIK  N+ L  +  V KL D
Sbjct: 1397 EEA-----AKMGLPEYLIRRYTREIVLAVNHLHENSIVHRDIKGANIFLTSNGHV-KLGD 1236

Query: 201  FGSAKQL-----VRGEPNVSYICSRYYRAPELIFGATD---YTSSIDVWSAGCVLAELLL 252
            FG + +L     + GE + + + +  Y APE +F   D   Y  + D+WS GCV+ E+  
Sbjct: 1235 FGCSVKLKSHTTMPGEFH-NLVGTTAYMAPE-VFTQNDQGGYGRAADIWSLGCVVIEMAT 1062

Query: 253  GQ 254
            G+
Sbjct: 1061 GK 1056
>23319
          Length = 2235

 Score = 78.6 bits (192), Expect = 4e-15,   Method: Compositional matrix adjust.
 Identities = 47/119 (39%), Positives = 67/119 (56%), Gaps = 3/119 (2%)
 Frame = +3

Query: 228 IFGATDYTSSIDVWSAGCVLAELL-LGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMN- 285
           ++ A  Y++SID+WSAGC+ AEL   G+P+FPG+   DQL  I K+LGTPT +Q   M  
Sbjct: 9   VYXAKMYSTSIDMWSAGCIFAELANAGRPLFPGNDDDDQLKRIFKLLGTPTEDQWPGMTQ 188

Query: 286 -PNYTEFKFPQIKAHPWTKVFRPRTPPEAIALCSRLLEYTPTARLTPLEACAHSFFDEL 343
            PNY  F    +    W +V  P+   +   L   LL   P+ R++  EA  H +F +L
Sbjct: 189 LPNYRMFPMYHVTTT-WQQVV-PKLNSKGRDLLQCLLVCCPSDRMSADEALQHPYFADL 359
>18921
          Length = 697

 Score = 77.0 bits (188), Expect = 1e-14,   Method: Compositional matrix adjust.
 Identities = 64/210 (30%), Positives = 107/210 (50%), Gaps = 4/210 (1%)
 Frame = +2

Query: 50  RPQEVSYTDTKVIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKN--RELQIMRKLDHC 107
           RP E  +     +G GS+G V+++   ++G+++AIK+V  D   +   +E+ IM++ D  
Sbjct: 17  RPPEDVFDILGKLGEGSYGSVFKSLHKETGQVLAIKQVPVDTDLQEIIKEISIMQQCDSK 196

Query: 108 NIVRLRYFFYSSGEKKDEVYLNLVLDYV-PETVYRVARHYSRAKQTLPVIYVKLYMYQLF 166
            IV+    +Y S  K  ++++  V++Y    +V  + R  ++   TL    +   +Y   
Sbjct: 197 YIVK----YYGSYFKNTDLWI--VMEYCGAGSVSDIMRLRNK---TLVEREIATILYYTL 349

Query: 167 RSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRG-EPNVSYICSRYYRAP 225
           + L Y+HS    HRDIK  N+LL+ +    KL DFG A QL        + I + Y+ AP
Sbjct: 350 KGLXYLHSRRKIHRDIKAGNILLNNEGHA-KLADFGVAGQLTDTMAKRNTVIGTPYWMAP 526

Query: 226 ELIFGATDYTSSIDVWSAGCVLAELLLGQP 255
           E+I     Y    D+WS G    E+  G+P
Sbjct: 527 EVI-QEIGYDCVADIWSLGITALEMAEGKP 613
>12721
          Length = 821

 Score = 76.6 bits (187), Expect = 2e-14,   Method: Compositional matrix adjust.
 Identities = 62/207 (29%), Positives = 104/207 (50%), Gaps = 7/207 (3%)
 Frame = +1

Query: 58  DTKVIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKNR------ELQIMRKLDHCNIVR 111
           D   IG GS G+V  A   D G  +A+KK+  D R + R      E+ +MR   H NIV 
Sbjct: 100 DFMKIGEGSTGIVCIATSRD-GRQMAVKKM--DLRKQQRRELLFNEVVVMRDYHHPNIVE 270

Query: 112 LRYFFYSSGEKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFRSLAY 171
           +    Y+S    DE+++  V++++           +R  +    + +        ++LA+
Sbjct: 271 M----YNSYLVNDELWV--VMEFMEGGALTDIVTNNRMDE----VQIATVCRACLKALAF 420

Query: 172 IHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRG-EPNVSYICSRYYRAPELIFG 230
           +H+ G+ HRDIK  ++LL  D  V KL DFG   Q+ +  +   S + + Y+ APE+I  
Sbjct: 421 LHANGVIHRDIKSDSILLSHDGKV-KLXDFGFCAQVTQDLQKRKSLVGTPYWMAPEVI-S 594

Query: 231 ATDYTSSIDVWSAGCVLAELLLGQPIF 257
              Y   +D+WS G ++ E++  +P F
Sbjct: 595 RLPYGPEVDIWSLGIMVMEMIDAEPPF 675
>03240
          Length = 1683

 Score = 75.1 bits (183), Expect = 5e-14,   Method: Compositional matrix adjust.
 Identities = 68/269 (25%), Positives = 113/269 (42%), Gaps = 54/269 (20%)
 Frame = -3

Query: 56   YTDTKVIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKNR-------ELQIMRKLDHCN 108
            +   K +G G+FG V   +  D+G L A+K + +    K         E  I+ + D+  
Sbjct: 1285 FEKIKTLGVGAFGEVSLCRKNDTGMLYAMKTLRKSDVLKRNQVAHVKAERDILAEADNEW 1106

Query: 109  IVRLRYFFYSSGEKKDEVYLNLVLDYVP--ETVYRVARHYSRAKQTLPVIYVKLYMYQLF 166
            +V+L Y F      +D  YL  V+DYVP  + +  + R      + L     + Y+ +L 
Sbjct: 1105 VVKLYYSF------QDHNYLYFVMDYVPGGDLMGLLIR-----MEILDEPLARFYVAELV 959

Query: 167  RSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFG---------SAKQLVRGEPNV--- 214
            +++  +H  G  HRDIKP N+L+D +  + KL DFG         ++K   R   +    
Sbjct: 958  QAIESVHRMGFIHRDIKPDNILIDRNGHI-KLTDFGLCTGFRWTHNSKYYQRDGTHARQD 782

Query: 215  ---------------------------------SYICSRYYRAPELIFGATDYTSSIDVW 241
                                             S + +  Y APE++     YTS  D W
Sbjct: 781  SMEVKCQLDEQCQCEILKPLERRRKREQRCLAHSLVGTPNYIAPEVLSRLGGYTSVCDWW 602

Query: 242  SAGCVLAELLLGQPIFPGDSGVDQLVEII 270
            S G +L E+L+G P F  ++  +   ++I
Sbjct: 601  SVGVILFEMLVGHPPFYANTPAETQYKVI 515
>09606
          Length = 1300

 Score = 72.8 bits (177), Expect = 2e-13,   Method: Compositional matrix adjust.
 Identities = 76/306 (24%), Positives = 131/306 (42%), Gaps = 27/306 (8%)
 Frame = -3

Query: 62   IGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFK-NRELQIMRKLDHCNIVRLRYFFYSSG 120
            +G G   ++Y+ +   +   VAI  + + KR +    +++   + H N+V+   ++ +S 
Sbjct: 1091 LGKGEHSIIYKGRRKGTINFVAIHCIEKCKRPEVTNTVRMTHDISHPNVVQFHEWYETSN 912

Query: 121  EKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFRSLAYIHSFGICHR 180
                  +L LV++    T   +A   ++    LP   ++ +   L   L YIHS GI   
Sbjct: 911  ------HLWLVVELC--TGGSLADILAQDHH-LPETSIRDFGIHLVTGLHYIHSLGILFH 759

Query: 181  DIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRY------------------- 221
            D++P  +LLD  + VLK  DFG +K  V GE N+  +  ++                   
Sbjct: 758  DLRPSKVLLDT-SGVLKFADFGLSK--VEGE-NLEELFFKFAEAGDQWNIQSAEEMMKQV 591

Query: 222  -------YRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLG 274
                   Y APE+  GA     S D+W+ GCV  E+  G P F G++      +I     
Sbjct: 590  PTSGSPTYMAPEVFQGAEPSIMS-DLWALGCVFYEMFSGHPPFLGET-----YDI----- 444

Query: 275  TPTREQIREMNPNYTEFKFPQIKAHPWTKVFRPRTPPEAIALCSRLLEYTPTARLTPLEA 334
              T++++        EF  P++K          +  PE + L   LL+   T RL+    
Sbjct: 443  --TKDKVLN-----KEFPLPKVKG----SRLSAKPSPEFLNLLESLLQKDSTRRLSWASL 297

Query: 335  CAHSFF 340
              H+F+
Sbjct: 296  VKHAFW 279
>15910
          Length = 1361

 Score = 70.9 bits (172), Expect = 9e-13,   Method: Compositional matrix adjust.
 Identities = 54/173 (31%), Positives = 84/173 (48%), Gaps = 3/173 (1%)
 Frame = +2

Query: 165 LFRSLAYIHSFGICHRDIKPQNLLLD--PDTAVLKLCDFGSAKQLVRGEPNVSYICSR-Y 221
           +   + YIH+ G+ HRD+KP+NLL +   D + LKL DFG ++ ++  E  +S +C    
Sbjct: 491 ILHGVQYIHANGVVHRDLKPENLLYECMTDDSKLKLADFGLSR-IIEPEVQMSTVCGTPG 667

Query: 222 YRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQI 281
           Y APE++ G   YT S+D+WS G +   LL G   F  ++  +   +IIK          
Sbjct: 668 YCAPEVLKG-DKYTPSVDMWSVGVIAYILLCGYEPFFAENEFEMYRKIIK---------- 814

Query: 282 REMNPNYTEFKFPQIKAHPWTKVFRPRTPPEAIALCSRLLEYTPTARLTPLEA 334
                   E+KF +     W+++        A  +  +LL   P  RLT  EA
Sbjct: 815 -------GEYKFDE---EYWSEI-----SENAKDVVRKLLVIDPKKRLTATEA 928
>13066
          Length = 551

 Score = 70.5 bits (171), Expect = 1e-12,   Method: Compositional matrix adjust.
 Identities = 59/199 (29%), Positives = 96/199 (48%), Gaps = 15/199 (7%)
 Frame = +3

Query: 61  VIGNGSFGVVYQAKLCDSGELVAIKKVLQD--KRFKNRELQIMRKLDHCNIVRLR----- 113
           V+ +G+F   Y   +  + +++  +K   D  ++F  REL ++ KLDH  I+++      
Sbjct: 12  VVVHGTFNDGYGRNIKLACKIIDKEKAPVDFVEKFFPRELDLLTKLDHPYIIQIHSILQR 191

Query: 114 ----YFFYSSGEKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFRSL 169
               + F    E+ D      +L Y+ E        + + KQ       K++ YQ+  +L
Sbjct: 192 XPKNFIFMRFAERGD------LLTYIQEV------GFVKEKQA------KIWFYQMTTAL 317

Query: 170 AYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLV--RGEPNVS--YICSRYYRAP 225
            Y+HS+ + HRD+K +N+LL     V KL DFG A   +   GE  +S  Y  S  Y AP
Sbjct: 318 NYLHSYDVAHRDLKCENILLSSHFNV-KLADFGFACACITESGEKYMSRTYCGSAAYAAP 494

Query: 226 ELIFGATDYTSSIDVWSAG 244
           E+++GA       D WS G
Sbjct: 495 EIVYGAPYAPKVADAWSLG 551
>12453
          Length = 680

 Score = 68.2 bits (165), Expect = 6e-12,   Method: Compositional matrix adjust.
 Identities = 39/144 (27%), Positives = 69/144 (47%), Gaps = 2/144 (1%)
 Frame = +3

Query: 244 GCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREM--NPNYTEFKFPQIKAHPW 301
           GC+  E+  G+P+FPG +  D+L  I K LGTPT + +  +  NP++     P  +    
Sbjct: 9   GCIFYEMACGRPLFPGSTVEDELHLIFKTLGTPTEDSLPSISRNPDFLALNLPHYQGEAL 188

Query: 302 TKVFRPRTPPEAIALCSRLLEYTPTARLTPLEACAHSFFDELRDPNVKLPNGRDTPALFN 361
             +  PR   + + L ++ L+Y    R++  ++  HSFF+ L      LP   DT + F 
Sbjct: 189 ITI-APRLDSDGLDLLAKFLKYNAKIRVSAADSLKHSFFNSLGPGVHMLP---DTVSAFT 356

Query: 362 FTTQELSSNPPLATILIPPHARIQ 385
                L  +P + +  +    +I+
Sbjct: 357 VPGISLHRDPGIRSSSVASTGKIR 428
>18484
          Length = 635

 Score = 68.2 bits (165), Expect = 6e-12,   Method: Compositional matrix adjust.
 Identities = 57/195 (29%), Positives = 87/195 (44%), Gaps = 2/195 (1%)
 Frame = +1

Query: 137 ETVYRVARHYSRAKQTLPVIYVKLYMYQLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVL 196
           + +YR+ +     K   PV     Y  ++   L ++H  GI +RD+K  N++LD +  + 
Sbjct: 1   DLMYRIQQ---EGKFKEPV--AAFYAAEIAVGLFFLHDQGIIYRDLKLDNVMLDSEGHI- 162

Query: 197 KLCDFGSAKQLVRGEPNVSYICSR-YYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQP 255
           K+ DFG  K+ + G+      C    Y APE++     Y+ S+D W+ G +L E+L GQP
Sbjct: 163 KIADFGMCKEGMTGDATTRTFCGTPDYIAPEIVL-YQPYSKSVDWWAYGVLLFEMLAGQP 339

Query: 256 IFPGDSGVDQLVEIIKVLGTPTREQIREMNPNYTEFKFPQIKAHPWTKVFRPRTPP-EAI 314
            F G+   D+L                          F  I  H    V  P+    EA+
Sbjct: 340 PFDGED-EDEL--------------------------FSSITDH---NVSYPKAMSREAV 429

Query: 315 ALCSRLLEYTPTARL 329
           +LC  LL   PT RL
Sbjct: 430 SLCKGLLMKNPTKRL 474
>06405
          Length = 1965

 Score = 68.2 bits (165), Expect = 7e-12,   Method: Compositional matrix adjust.
 Identities = 64/238 (26%), Positives = 118/238 (49%), Gaps = 12/238 (5%)
 Frame = +1

Query: 48  PDRPQEVSYTDTKV---IGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKN---RELQIM 101
           PDR  E+  T+  +   +G G +G VY+A      ++VA+K + +D    N    E  IM
Sbjct: 235 PDR-WEIERTEIAMKHRLGGGQYGDVYEAMWKRYNKIVAVKTLKEDTMALNDFLEEAAIM 411

Query: 102 RKLDHCNIVRLRYFFYSSGEKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLY 161
           +++ H N+V+L       G    E    +V +++P          S  ++  P     +Y
Sbjct: 412 KEMKHPNLVQLL------GVCTREPPFYIVTEFMPHGNLLDYLRSSTREENGPTAL--MY 567

Query: 162 MY-QLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSR 220
           M  Q+   +AY+ +    HRD+  +N L+  D+ ++K+ DFG A+ L++ +   ++I ++
Sbjct: 568 MATQIASGMAYLETKNFIHRDLAARNCLVA-DSNMVKVADFGLAR-LMKDDTYTAHIGAK 741

Query: 221 Y---YRAPE-LIFGATDYTSSIDVWSAGCVLAEL-LLGQPIFPGDSGVDQLVEIIKVL 273
           +   + APE L F    +++  D+W+ G +L EL   G   +PG     +L E+  +L
Sbjct: 742 FPIKWTAPEGLAFNR--FSTRSDIWAFGVLLWELATYGMSPYPG----VELTEVYHLL 897
>30755
          Length = 1137

 Score = 67.0 bits (162), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 37/108 (34%), Positives = 60/108 (55%), Gaps = 2/108 (1%)
 Frame = +2

Query: 158 VKLYMYQLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQ-LVRGEPNVSY 216
            + Y  ++  +L Y+HS GI +RD+K +NLLLD D  + K+ DFG  K+ +  G    ++
Sbjct: 38  TRFYGAEIISALGYLHSQGIIYRDLKLENLLLDKDGHI-KVADFGLCKEDITYGRTTKTF 214

Query: 217 ICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQ-PIFPGDSGV 263
             +  Y APE +    DY  ++D W  G V+ E++ G+ P +  D  V
Sbjct: 215 CGTPEYLAPE-VLDDNDYGRAVDWWGTGVVMYEMICGRLPFYNRDHDV 355
>19301
          Length = 712

 Score = 65.9 bits (159), Expect = 3e-11,   Method: Compositional matrix adjust.
 Identities = 46/150 (30%), Positives = 78/150 (52%)
 Frame = +2

Query: 55  SYTDTKVIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKNRELQIMRKLDHCNIVRLRY 114
           S TD + +G+G+ G V+  KLC   E VA+KKV   +  K  +++ +RKL+H NI+  + 
Sbjct: 308 SITDLEWLGSGAQGAVFLGKLC--AEEVAVKKV---RDIKETDIRNLRKLNHPNIISFK- 469

Query: 115 FFYSSGEKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFRSLAYIHS 174
                G         ++++Y P   Y       R  + +P   V  +  Q+   + Y+HS
Sbjct: 470 -----GVCTQAPCYCIIMEYCP---YGQLYEVLRDGKEIPPALVLDWSKQIASGMNYLHS 625

Query: 175 FGICHRDIKPQNLLLDPDTAVLKLCDFGSA 204
             I HRD+K  N+L+  +  V+K+ DFG++
Sbjct: 626 HKIIHRDLKSPNVLVAKND-VVKISDFGTS 712
>01966
          Length = 1735

 Score = 65.1 bits (157), Expect = 5e-11,   Method: Compositional matrix adjust.
 Identities = 40/127 (31%), Positives = 66/127 (51%), Gaps = 4/127 (3%)
 Frame = -3

Query: 218  CSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPT 277
            C      P    GA+ Y++ +DVWS G + A++L+  PIF GDS +DQL +I +++GTPT
Sbjct: 1223 CDLVVPGPRDPHGASKYSTPVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIFRIIGTPT 1044

Query: 278  REQIREMN--PNYTEFKFPQIKAHPWTKVFRPRTPPEAIA--LCSRLLEYTPTARLTPLE 333
             +   E +  P +    FP  K     K+    T  +++   L  R L+  P  R++  +
Sbjct: 1043 EQTWPEFHKLPAFNGM-FPLWKE---GKLSETLTDLDSLGLDLIERTLKCDPAQRISCKK 876

Query: 334  ACAHSFF 340
               H++F
Sbjct: 875  MLQHAYF 855

 Score = 64.7 bits (156), Expect = 6e-11,   Method: Compositional matrix adjust.
 Identities = 50/162 (30%), Positives = 76/162 (46%), Gaps = 11/162 (6%)
 Frame = -1

Query: 96   RELQIMRKLDHCNIVRL--------RYFFYSSGEKKDEVYLNLVLDYVPETVYRVARHYS 147
            RE+ ++R+L H NIV L        R F        D   L + +D  PE V    R   
Sbjct: 1567 REIAMLRELRHTNIVCLEDVIMEDERLFLVFEFLSMD---LKMYIDKFPEGVVLDRR--- 1406

Query: 148  RAKQTLPVIYVKLYMYQLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQL 207
                      VK Y++Q+   + + H   I HRD+KPQNLL++  T  +K+ DFG A+  
Sbjct: 1405 ---------LVKSYVFQIVTGINFCHQRRIVHRDLKPQNLLIN-HTGAIKIADFGMARTF 1256

Query: 208  VRGEPNVSY---ICSRYYRAPELIFGATDYTSSIDVWSAGCV 246
                P  +Y   + + +YRAPE++ G     S+   W+ G +
Sbjct: 1255 --ALPVRAYTHEVVTLWYRAPEILMGP---QSTPPXWTCGAL 1145
>09007
          Length = 1440

 Score = 64.3 bits (155), Expect = 9e-11,   Method: Compositional matrix adjust.
 Identities = 63/232 (27%), Positives = 108/232 (46%), Gaps = 15/232 (6%)
 Frame = -1

Query: 35  SKVTTVVATPGQGPDRPQEVSYTDTKVIGNGSFGVVYQAKL-CDSGE--LVAIKKVLQDK 91
           S+  + V  P +G     +     +K +G G FG V QA    +SGE   VA+K + +DK
Sbjct: 936 SRPVSAVVRPARGKQLISKDCVALSKSLGQGHFGTVRQAIWTAESGEKVQVAVKCLSKDK 757

Query: 92  RFKN-----RELQIMRKLDHCNIVRLRYFFYSSGEKKDEVYLNLVLDYVP-ETVYRVARH 145
             K+     +E  IM+ LDH NIVR+      +G       + LV +  P  ++    + 
Sbjct: 756 IHKDGQEFLKETAIMQMLDHENIVRVYGVVMDNGAD-----IMLVTELAPMRSLLECVKE 592

Query: 146 YSRAKQTLPVIYVKLYMYQLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCD----- 200
            S A+    V  +  +  Q+   ++Y+ S  + HRD+  +N+LL   + V K+ D     
Sbjct: 591 VS-ARVDFSVPRLCDFSQQVCDGMSYLESKRLVHRDLAARNILLFSKSKV-KISDVGVSG 418

Query: 201 -FGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELL 251
             G+ K+  + +  +    +  + APE  F    ++S+ DVW+ G +L E  
Sbjct: 417 ALGAGKEYYQSQQTIHLQNAVAWCAPE-SFRNLCFSSASDVWAFGVLLWEFF 265
>26560
          Length = 398

 Score = 63.9 bits (154), Expect = 1e-10,   Method: Composition-based stats.
 Identities = 37/113 (32%), Positives = 62/113 (54%), Gaps = 4/113 (3%)
 Frame = -1

Query: 158 VKLYMYQLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYI 217
           V+ Y  ++   L ++HS  + +RD+KP N+LLD +  V ++ D G A    +  P+ S +
Sbjct: 350 VRFYAAEVMLGLEHMHSRFVVYRDLKPANILLDENGHV-RISDLGLACDFSKKRPHAS-V 177

Query: 218 CSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIF----PGDSGVDQL 266
            +  Y APE++     Y SS D +S GC+L +LL G   F     G + +D++
Sbjct: 176 GTHGYMAPEVLMKGQSYDSSADWFSFGCMLYKLLKGHSPFRQHNQGQARIDRM 18
>14116
          Length = 1017

 Score = 62.4 bits (150), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 61/211 (28%), Positives = 90/211 (42%), Gaps = 21/211 (9%)
 Frame = -1

Query: 62  IGNGSFGVVYQAKLC---DSGELVAIKKVLQDKRFKNRELQ-------IMRKLDHCNIVR 111
           IG G+FG V +  L      G+++   K L +   +  ELQ       IM+   H N++ 
Sbjct: 612 IGKGNFGCVKRGFLTLPEQKGDILVAVKTLHNNNPREIELQSFLQEALIMKDFHHSNVLT 433

Query: 112 LRYFFYSSGEKKDEVYLNLVLDYVPETVYRVARH-----YSRAKQTLPVIY-VKLYMYQL 165
           L             + + L LD +P  V    +H     Y R  Q  P I  + +Y   +
Sbjct: 432 L-------------IGICLNLDDMPLVVLPFMKHGDLLTYIRDDQHQPTIKDLIMYGVDI 292

Query: 166 FRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSA-----KQLVRGEPNVSYICSR 220
            R + Y+      HRD+  +N +LD D  V K+ DFG A     K+    E   + +  +
Sbjct: 291 ARGMDYLAGLKFVHRDLAARNCMLDEDFHV-KVADFGLARDIYEKEYYSSENKKAKLPVK 115

Query: 221 YYRAPELIFGATDYTSSIDVWSAGCVLAELL 251
           +     L  G  +Y S  DVWS G VL ELL
Sbjct: 114 WMALESLEKG--NYDSKTDVWSYGVVLWELL 28
>31885
          Length = 529

 Score = 62.0 bits (149), Expect = 4e-10,   Method: Compositional matrix adjust.
 Identities = 54/158 (34%), Positives = 77/158 (48%), Gaps = 4/158 (2%)
 Frame = -2

Query: 98  LQIMRKLDHCNIVRLRYFFYSSGEKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIY 157
           + ++ +LDH  +V L Y F      +DE  L +V+D     +    R++ + + +     
Sbjct: 519 VDMLTRLDHPFLVNLWYAF------QDEEDLFMVVDLF---LGGDLRYHMQQEVSFREDC 367

Query: 158 VKLYMYQLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYI 217
           VK Y+ QL   L Y+ S  I HRDIKP N+LLD +     + DF  A QL   E   S  
Sbjct: 366 VKFYLCQLALVLDYLRSQKIVHRDIKPDNILLD-EQGHCHVTDFNIATQLEDDELATSTS 190

Query: 218 CSRYYRAPELIFGATD----YTSSIDVWSAGCVLAELL 251
            +R Y APE+   A +    Y   +D WS G  L ELL
Sbjct: 189 GTRPYMAPEVYGVAINERRGYGFPVDWWSLGVSLFELL 76
>12786
          Length = 460

 Score = 61.6 bits (148), Expect = 6e-10,   Method: Compositional matrix adjust.
 Identities = 41/135 (30%), Positives = 65/135 (48%), Gaps = 24/135 (17%)
 Frame = -3

Query: 147 SRAKQT--LPVIYVKLYMYQLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSA 204
           +RAKQ   L  + +K Y  ++ R++  +H+ G+ H D+KP N +L      LKL DFG A
Sbjct: 443 ARAKQEQGLDRMMIKFYWREMLRAVKALHNEGVIHSDLKPANFMLVAGN--LKLIDFGIA 270

Query: 205 KQLVRGEPNV---SYICSRYYRAPELIFGATDYTSS-------------------IDVWS 242
             L + + +V   S + +  Y +PE I  A D ++                     DVWS
Sbjct: 269 NTLQQDKTSVLKDSRVGTPSYMSPEAIMAACDDSADDSMEEDGHRTKPKYKVGVRSDVWS 90

Query: 243 AGCVLAELLLGQPIF 257
            GC+L  ++ G+  F
Sbjct: 89  LGCILYNMVYGRTPF 45
>01718
          Length = 959

 Score = 60.8 bits (146), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 52/204 (25%), Positives = 92/204 (45%), Gaps = 7/204 (3%)
 Frame = +3

Query: 62  IGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKN--RELQIMRKLDHCNIVRLRYFFYSS 119
           IG G F  V++     +G+++A+K         N  RE+Q++ +L H NI+R        
Sbjct: 171 IGAGFFSEVFKVTHRITGQVMALKMNTMTSNRHNMLREVQLLNRLQHANILRFMGVCVHE 350

Query: 120 GEKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFRSLAYIHSFGICH 179
           G+      L+ + +Y+P     + +   +  + LP          L R L Y+HS    H
Sbjct: 351 GQ------LHALTEYIPSG--NLEQLLEKKDEELPWTQRIQLTLGLARGLDYLHSTRFIH 506

Query: 180 RDIKPQNLLL---DPDTAVLKLCDFGSAKQLVR--GEPNVSYICSRYYRAPELIFGATDY 234
           RD+  +N+L+   D       + DFG A ++     +  +  + S Y+ APE++ G   Y
Sbjct: 507 RDLTSKNILIRREDNHGYHAVIADFGLATKIPDPLDKEKLPTVGSPYWMAPEVLNGHF-Y 683

Query: 235 TSSIDVWSAGCVLAELLLGQPIFP 258
               D++S G ++ E+    P  P
Sbjct: 684 NERADLFSVGIIMCEITARIPADP 755
>18287
          Length = 678

 Score = 60.5 bits (145), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 40/122 (32%), Positives = 55/122 (45%), Gaps = 11/122 (9%)
 Frame = -3

Query: 234 YTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPNYTEFKF 293
           Y  SID+WS GC+ AELL  + +F     V QL  II ++GTP         P   E   
Sbjct: 673 YDYSIDIWSVGCIFAELLSRRILFQAQGPVQQLDMIINLVGTP--------RPEDMERAC 518

Query: 294 PQIKAHPWTKVFR-----------PRTPPEAIALCSRLLEYTPTARLTPLEACAHSFFDE 342
              + H   + FR           P    EA+ L +R+L   P  R++  EA +H + DE
Sbjct: 517 EGARNHILNQPFRRQNLLTLYNLSPHATHEAVRLLTRMLILNPKNRISAEEALSHPYLDE 338

Query: 343 LR 344
            R
Sbjct: 337 GR 332
>01392
          Length = 1806

 Score = 60.1 bits (144), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 39/119 (32%), Positives = 61/119 (51%), Gaps = 12/119 (10%)
 Frame = -1

Query: 158  VKLYMYQLFRSLAYIHSFGICHRDIKPQNLLLD--PDTAVLKLCDFGSAKQL-VRGEPN- 213
              L +  + R+L ++HS GI HRD+KP+N+L +   D   +K+CDF  A  +   G+   
Sbjct: 1785 ASLVVRHIARALDFLHSKGIAHRDLKPENILCEHLDDVVPVKICDFDLASGISCDGDGTK 1606

Query: 214  ----VSYICSRYYRAPELIFG----ATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVD 264
                ++ + S  Y APE++      +  Y    D+WS G +L  +L G P F G  G D
Sbjct: 1605 TPELLTPVGSAEYMAPEVVDAWVGDSFSYDKRCDLWSLGIILYIMLCGYPPFYGQCGED 1429
>13212
          Length = 1067

 Score = 59.3 bits (142), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 55/183 (30%), Positives = 80/183 (43%), Gaps = 5/183 (2%)
 Frame = -1

Query: 163 YQLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFG-SAKQLVRGEPNVSYICSRY 221
           +++  +L ++H   + HRDIK  N+LL  D  V KL DFG SAK     +   ++I + Y
Sbjct: 959 HEMCMALDFLHRHHVIHRDIKAGNVLLTIDGEV-KLADFGVSAKNTQTQQKRDTFIGTPY 783

Query: 222 YRAPELI----FGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPT 277
           + APE++       T Y    D+WS G  L E      I P +  +  +  +IK      
Sbjct: 782 WMAPEVVLCETLKDTPYDFKADIWSLGVTLIEFAQ---IEPPNKEMHPMRVLIK------ 630

Query: 278 REQIREMNPNYTEFKFPQIKAHPWTKVFRPRTPPEAIALCSRLLEYTPTARLTPLEACAH 337
              I + +P   E      K   WTK+F+     + IA C   L   P  R T  E   H
Sbjct: 629 ---IHKSDPPTLE------KPKKWTKLFK-----DFIAKC---LVKDPNLRPTAAELLEH 501

Query: 338 SFF 340
            F 
Sbjct: 500 PFM 492
>14420
          Length = 528

 Score = 58.5 bits (140), Expect = 5e-09,   Method: Compositional matrix adjust.
 Identities = 32/93 (34%), Positives = 53/93 (56%), Gaps = 1/93 (1%)
 Frame = +2

Query: 164 QLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVS-YICSRYY 222
           +  ++L ++H   + HRDIK  N+LL  D +V KL DFG   QL   +   S  + + Y+
Sbjct: 221 ECLQALEFLHENQVIHRDIKSDNILLGMDGSV-KLTDFGFCAQLSPEQSKRSTMVGTPYW 397

Query: 223 RAPELIFGATDYTSSIDVWSAGCVLAELLLGQP 255
            APE++     Y  ++D+WS G +  E++ G+P
Sbjct: 398 MAPEVV-TRKQYGPTVDIWSLGVMCIEMIEGEP 493
>03294
          Length = 1684

 Score = 57.4 bits (137), Expect = 9e-09,   Method: Compositional matrix adjust.
 Identities = 35/107 (32%), Positives = 58/107 (54%), Gaps = 4/107 (3%)
 Frame = -1

Query: 238  IDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMN--PNYTEFKFPQ 295
            +DVWS G + A++L+  PIF GDS +DQL +I +++GTPT +   E +  P +    FP 
Sbjct: 1672 VDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIFRIIGTPTEQTWPEFHKLPAFNGM-FPL 1496

Query: 296  IKAHPWTKVFRPRTPPEAIA--LCSRLLEYTPTARLTPLEACAHSFF 340
             K     K+    T  +++   L  R L+  P  R++  +   H++F
Sbjct: 1495 WKE---GKLSETLTDLDSLGLDLIERTLKCDPAQRISCKKMLQHAYF 1364
>31489
          Length = 329

 Score = 57.0 bits (136), Expect = 1e-08,   Method: Composition-based stats.
 Identities = 29/91 (31%), Positives = 50/91 (54%)
 Frame = +3

Query: 98  LQIMRKLDHCNIVRLRYFFYSSGEKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIY 157
           ++I++   H NI+ +R          D   +++V D +   ++R+   YS   Q L   +
Sbjct: 3   IKILKHFKHDNIISIREILKPKDSYHDFKDIHVVFDLMESDLHRII--YS--DQPLTEEH 170

Query: 158 VKLYMYQLFRSLAYIHSFGICHRDIKPQNLL 188
           ++ ++YQ+ R L YIHS  + HRD+KP NLL
Sbjct: 171 IRYFLYQILRGLKYIHSANVVHRDLKPSNLL 263
>27546
          Length = 426

 Score = 55.8 bits (133), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 39/126 (30%), Positives = 62/126 (49%), Gaps = 11/126 (8%)
 Frame = -1

Query: 91  KRFKNRELQIMRKLDHCNIVRLR---------YFFYSSGEKKDEVYLNLVLDYVPETVYR 141
           K+F  REL+I+ +LDH NI+++          + F    EK D +               
Sbjct: 348 KKFFPRELEILTRLDHPNIIQIHSILQRGPKIFIFMRYAEKGDML--------------- 214

Query: 142 VARHYSRAKQTLPV--IYVKLYMYQLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLC 199
                S  K+T P+     K++ +Q+ ++L Y+HS  I HRD+K +N+LL     V K+ 
Sbjct: 213 -----SHIKKTGPIDEAQTKVWFFQMAKALQYLHSHDIAHRDLKCENILLSKRLNV-KIA 52

Query: 200 DFGSAK 205
           DFG A+
Sbjct: 51  DFGFAR 34
>17975
          Length = 449

 Score = 54.7 bits (130), Expect = 7e-08,   Method: Compositional matrix adjust.
 Identities = 42/152 (27%), Positives = 76/152 (50%), Gaps = 6/152 (3%)
 Frame = +3

Query: 67  FGVVYQAKLCDSGELVAIKKVLQDK------RFKNRELQIMRKLDHCNIVRLRYFFYSSG 120
           F VV  A+   +GE VA+K + + K          +E++ M+ + H N+VRL    Y   
Sbjct: 6   FAVVKLARHVFTGEKVAVKVIDKTKLDEVSRSHLFQEVRCMKLVQHPNVVRL----YEVI 173

Query: 121 EKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFRSLAYIHSFGICHR 180
           + + ++YL L L    +    + RH    ++ L     K Y  Q+  +++Y H   + HR
Sbjct: 174 DTQTKLYLILELGDGGDMYDYIMRHSGGLEEKLA----KRYFRQIVEAISYCHKLHVVHR 341

Query: 181 DIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEP 212
           D+KP+N++      ++KL DFG +  L++ + 
Sbjct: 342 DLKPENVVFFEKPGLVKLTDFGFSTCLLQAKA 437
>27405
          Length = 532

 Score = 53.5 bits (127), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 54/190 (28%), Positives = 90/190 (47%), Gaps = 14/190 (7%)
 Frame = -3

Query: 66  SFGVVYQAKLCDSGELVAIKKVLQDKRFKNR-------ELQIMRKLDHCN-----IVRLR 113
            FG VY  +  D+G++ A+K  L  KR K +         +IM  L         IV + 
Sbjct: 530 GFGEVYGCRKADTGKMYAMK-CLDKKRIKMKGGETLALNERIMLSLVSTGEGSPFIVCMT 354

Query: 114 YFFYSSGEKKDEVYLNLVLDYV--PETVYRVARHYSRAKQTLPVIYVKLYMYQLFRSLAY 171
           Y F +  EK     L  +LD +   +  Y +++H    ++      V+ Y  ++   L +
Sbjct: 353 YAFQTP-EK-----LCFILDLMNGGDLHYHLSQHGVFTEKE-----VRFYAAEVMLGLEH 207

Query: 172 IHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGA 231
           +HS  + +RD+KP N+LLD +  V ++ D G A    + +P+ S + +  Y APE++   
Sbjct: 206 MHSRFVVYRDLKPANILLDENGHV-RISDLGLACDFSKKKPHAS-VGTHGYMAPEVLMKG 33

Query: 232 TDYTSSIDVW 241
             Y SS D W
Sbjct: 32  QAYDSSAD-W 6
>18401
          Length = 463

 Score = 53.5 bits (127), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 35/140 (25%), Positives = 61/140 (43%), Gaps = 16/140 (11%)
 Frame = -3

Query: 217 ICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGT- 275
           + +R+YRAPE+I     ++   DVWS GC++ EL  G  +F      + L  + ++LG+ 
Sbjct: 449 VSTRHYRAPEVIL-ELGWSHPCDVWSVGCIMFELYTGYTLFQTHDNKEHLAMMERILGSL 273

Query: 276 PTREQIREMNPNYTEF------------KFPQIKAHPWTKVFRPRTPPEA---IALCSRL 320
           P R   +     Y               ++ +    P  +  + R   +      L  +L
Sbjct: 272 PYRMAKKTKKQKYFHHGRLDVPERSSMARYVRENTKPLLRYVKDRENKDHQQLFDLMKKL 93

Query: 321 LEYTPTARLTPLEACAHSFF 340
           L Y  ++R + L+A  H FF
Sbjct: 92  LAYEASSRYSLLQALQHPFF 33
>26711
          Length = 405

 Score = 52.4 bits (124), Expect = 4e-07,   Method: Composition-based stats.
 Identities = 33/104 (31%), Positives = 53/104 (50%), Gaps = 1/104 (0%)
 Frame = -2

Query: 164 QLFRSLAYIHSFGICHRDIKPQNLLLDPDTA-VLKLCDFGSAKQLVRGEPNVSYICSRYY 222
           Q+   L ++H+ G+ H D+KP NLLL  D    ++L DFG A++L   +       +  +
Sbjct: 392 QVLDILQHVHAQGVVHMDLKPSNLLLSGDKLDSVQLIDFGLARKLYPPQETFLNHGTPGF 213

Query: 223 RAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQL 266
            +PE +      +++ DVW  G +   LL GQ  F  DS  + L
Sbjct: 212 TSPEAL-DVKPISTASDVWGVGVLAYILLSGQSPFQADSATESL 84
>07940
          Length = 1336

 Score = 52.4 bits (124), Expect = 4e-07,   Method: Compositional matrix adjust.
 Identities = 36/102 (35%), Positives = 53/102 (51%), Gaps = 4/102 (3%)
 Frame = -3

Query: 161 YMYQLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSR 220
           Y YQ+ R + Y+ S    HRD+  +N+L+  +  VLK+ DFG  + L + +        R
Sbjct: 332 YAYQVARGMEYLASKQCIHRDLAARNVLV-AEEYVLKIADFGLTRNLQQFDYYRKTTDGR 156

Query: 221 Y---YRAPELIFGATDYTSSIDVWSAGCVLAELL-LGQPIFP 258
               + APE +F    YTS  DVWS G +L E+  LG   +P
Sbjct: 155 LPVKWMAPEALFD-RKYTSKSDVWSYGVLLWEIFTLGGNPYP 33
>11185
          Length = 473

 Score = 51.6 bits (122), Expect = 7e-07,   Method: Compositional matrix adjust.
 Identities = 38/122 (31%), Positives = 54/122 (44%), Gaps = 26/122 (21%)
 Frame = +1

Query: 158 VKLYMYQLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYI 217
           ++ +   L   L YIHS GI   D++P  +LLD  + VLK  DFG +K  V GE N+  +
Sbjct: 7   IRDFGIHLVTGLHYIHSLGILFHDLRPSKVLLDT-SGVLKFADFGLSK--VEGE-NLEEL 174

Query: 218 CSRY--------------------------YRAPELIFGATDYTSSIDVWSAGCVLAELL 251
             ++                          Y APE+  GA     S D+W+ GCV  E+ 
Sbjct: 175 FFKFAEAGDQWNIQSAEEMMKQVPTSGSPTYMAPEVFQGAEPSIMS-DLWALGCVFYEMF 351

Query: 252 LG 253
            G
Sbjct: 352 SG 357
>19761
          Length = 473

 Score = 51.2 bits (121), Expect = 7e-07,   Method: Compositional matrix adjust.
 Identities = 38/128 (29%), Positives = 63/128 (49%), Gaps = 6/128 (4%)
 Frame = -3

Query: 153 LPVIYVKLYMYQLFRSLAYIHSFG--ICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVR- 209
           LP   +  ++ Q   +L Y+H+    I HRD+KPQN+ +     V +L D G A++L   
Sbjct: 432 LPERLIVCWLMQTASALNYMHTHTPVILHRDLKPQNIYVTEKGDV-RLGDLGLARKLTGP 256

Query: 210 GEPNVSYICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQ---L 266
            +   S + +  Y +PE I     Y S  D+WS GCV  ++        G  G D+   +
Sbjct: 255 ADFATSQVGTIMYLSPE-ILSQQPYNSKSDIWSLGCVFYDI-------TGKKGSDEMGVM 100

Query: 267 VEIIKVLG 274
             +++V+G
Sbjct: 99  FLLVQVMG 76
>19094
          Length = 898

 Score = 51.2 bits (121), Expect = 8e-07,   Method: Compositional matrix adjust.
 Identities = 35/95 (36%), Positives = 48/95 (50%), Gaps = 2/95 (2%)
 Frame = +1

Query: 162 MYQLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQL--VRGEPNVSYICS 219
           +Y   + L Y+HS    HRDIK  N+LL+ +    KL DFG A QL     + N + I +
Sbjct: 76  LYYTLKGL*YLHSRRKIHRDIKAGNILLNNEGHA-KLADFGVAGQLTDTMAKRN-TVIGT 249

Query: 220 RYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQ 254
            Y+ APE+I     Y    D+WS G    E+  G 
Sbjct: 250 PYWMAPEVIQ-EIGYDCVADIWSLGITALEMAEGN 351
>21433
          Length = 590

 Score = 49.7 bits (117), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 36/96 (37%), Positives = 51/96 (53%), Gaps = 1/96 (1%)
 Frame = +2

Query: 161 YMYQLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSR 220
           Y+YQL  +L Y H   + HRDIKP+NLLL      LK+ DFG +            +C  
Sbjct: 182 YIYQLSSALEYCHYRKVIHRDIKPENLLLG-LKGDLKIADFGWSVHAPSSRRTT--MCGT 352

Query: 221 Y-YRAPELIFGATDYTSSIDVWSAGCVLAELLLGQP 255
             Y  PE++ G T +  ++D+WS G +  E L+G P
Sbjct: 353 LDYLPPEMVEGKT-HDENVDLWSLGVLCYEFLVGTP 457
>14477
          Length = 493

 Score = 49.3 bits (116), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 52/179 (29%), Positives = 84/179 (46%), Gaps = 9/179 (5%)
 Frame = -1

Query: 57  TDTKVIGNGSFGVVYQAKLC--DSGELVAIKKVLQDKRFK-------NRELQIMRKLDHC 107
            D   +G G+FG V +  +C  D  E+    KVL++            +E ++M+K+DH 
Sbjct: 481 MDELKLGAGNFGSVMKG-VCRLDDREIPVAIKVLKNADLDPSVQSELIKEAEVMKKMDHM 305

Query: 108 NIVRLRYFFYSSGEKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFR 167
           +IVRL       GE      + LVL+     +  + +   + K  LP+  +   M+Q+ +
Sbjct: 304 HIVRL--IGLCEGET-----MMLVLELAK--LGPLNKFLPKNKH-LPLWNILELMWQVSQ 155

Query: 168 SLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPE 226
            + Y+ +    HRD+  +N+LL  D    K+ DFG +K L R E N       YY A E
Sbjct: 154 GMEYLEANKFVHRDLAARNILL-CDEHFAKISDFGMSKTLSR-ENN-------YYMAQE 5
>00715
          Length = 1788

 Score = 48.5 bits (114), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 38/119 (31%), Positives = 50/119 (42%), Gaps = 23/119 (19%)
 Frame = +1

Query: 164 QLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQL---------------- 207
           Q+ R L Y+HS  I H D+KP N LL  D   L++ DFG   QL                
Sbjct: 262 QMARGLHYLHSINIVHLDLKPANCLLTRDLK-LRIADFGCCHQLTPTGLDMGEREGGMAG 438

Query: 208 -------VRGEPNVSYICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPG 259
                  V+G        +  YRAPEL+ G      S DV+S G  L ++   Q  + G
Sbjct: 439 NELELTPVQGAWKNELAGTLAYRAPELLKGLQPSVRS-DVYSLGITLWQMCTRQGPYEG 612
>04852
          Length = 1462

 Score = 47.0 bits (110), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 32/97 (32%), Positives = 50/97 (51%), Gaps = 2/97 (2%)
 Frame = +1

Query: 161 YMYQLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSR 220
           Y +Q+ R + ++ S    HRD+  +N+L+  +  VLK+ DFG ++     +         
Sbjct: 340 YAFQIARGMEFLASRKCIHRDLAARNVLV-TEEHVLKIADFGLSRTGDYYKKRSGGRLPV 516

Query: 221 YYRAPELIFGATDYTSSIDVWSAGCVLAEL--LLGQP 255
            + APE +F    YT+  DVWS G VL E+  L G P
Sbjct: 517 KWMAPEALFDMR-YTTKSDVWSFGVVLWEIFSLGGMP 624
>28157
          Length = 400

 Score = 46.6 bits (109), Expect = 2e-05,   Method: Composition-based stats.
 Identities = 38/128 (29%), Positives = 62/128 (48%), Gaps = 5/128 (3%)
 Frame = +3

Query: 82  VAIKKVL--QDKRFKNRELQIMRKLDHCNIVRLRYFFYSSGEKKDEVYLNLVLDYVPETV 139
           VA+K++   Q+K+   +EL+ + ++ H NIV L       G  +D   + LV++Y     
Sbjct: 9   VAVKRIESEQEKKSFMQELKQLSRVSHPNIVCL------YGACRDHP-VCLVMEYAEGGS 167

Query: 140 YRVARHYSRAKQTLPVIYVKLYMYQLFRSLAYIHSF---GICHRDIKPQNLLLDPDTAVL 196
                H S  +      +   ++ Q    + Y+H      + HRD+KP NLLL      L
Sbjct: 168 LYNVLHGSGPQPQYTAAHAMNWLLQCALGVEYLHGMKPKALIHRDLKPPNLLLIQCGTKL 347

Query: 197 KLCDFGSA 204
           K+CDFG+A
Sbjct: 348 KICDFGTA 371
>21808
          Length = 1011

 Score = 46.6 bits (109), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 44/177 (24%), Positives = 87/177 (49%), Gaps = 4/177 (2%)
 Frame = +1

Query: 97  ELQIMRKLDHCNIVRLRYFFYSSGEKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVI 156
           E QIM+KL H  +++L    Y+   + D +++   L     ++    +   R  +   +I
Sbjct: 82  EAQIMKKLRHPKLIQL----YAVCTQDDPIFIITEL-MKNGSLLEFLQGKGRVLKLPALI 246

Query: 157 YVKLYMYQLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSY 216
            +     Q+   +AY+ S    HRD+  +N+L+  D   +K+ DFG A+ +++ +   + 
Sbjct: 247 DIGA---QIACGMAYLESQNYIHRDLAARNILVS-DNNTVKIADFGLAR-VIKEDEYEAR 411

Query: 217 ICSRY---YRAPELIFGATDYTSSIDVWSAGCVLAE-LLLGQPIFPGDSGVDQLVEI 269
           + +R+   + APE       +T   DVWS G +L E +  G+  +PG +  + L ++
Sbjct: 412 VGARFPIKWTAPEAA-NYNRFTIKSDVWSFGILLTETVTYGRVPYPGMTNAEVLHQV 579
>11404
          Length = 563

 Score = 45.1 bits (105), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 49/162 (30%), Positives = 79/162 (48%), Gaps = 13/162 (8%)
 Frame = +1

Query: 41  VATPGQG-PDRPQEVSYTDTKVIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKNRE-- 97
           + +PG+   DR     Y    +IG GSFG V +A      E VAIK +   K F N+   
Sbjct: 112 IISPGEKWADR-----YEIDSLIGKGSFGQVVKAYDHTDNEQVAIKIIKNKKPFLNQAQI 276

Query: 98  ----LQIMRKLDHCN---IVRL-RYFFYSSGEKKDEVYLNLVLDYVPETVYRVARHYSRA 149
               L++M + D  N   IVRL R+F + S       +L LV + +   +Y + R+ +  
Sbjct: 277 EVKLLEMMNRHDTDNKYYIVRLKRHFMFRS-------HLCLVFELLSYNLYDLLRNTNFR 435

Query: 150 KQTLPVIYVKLYMYQLFRSLAYIHS--FGICHRDIKPQNLLL 189
             +L +   + +  QL  +L ++ +    I H D+KP+N+LL
Sbjct: 436 GVSLNL--TRKFAQQLCTALLFLATPEMSIIHCDLKPENILL 555
>21079
          Length = 878

 Score = 44.7 bits (104), Expect = 7e-05,   Method: Compositional matrix adjust.
 Identities = 28/95 (29%), Positives = 52/95 (54%), Gaps = 2/95 (2%)
 Frame = +1

Query: 161 YMYQLFRSLAYIHSFGICHRDIKPQNLLLDPDTA-VLKLCDFGSAKQLVRGEPNVSYICS 219
           ++ Q+   + Y+H+  I H D+KP+N+L   D +  +K+ DFG A+    G+       +
Sbjct: 142 FVRQICSGVGYMHTQSILHLDLKPENVLCVSDNSNQIKIIDFGLARFYKPGDSLQVLFGT 321

Query: 220 RYYRAPELI-FGATDYTSSIDVWSAGCVLAELLLG 253
             + APE++ +   ++T+  D+WS G +   LL G
Sbjct: 322 PEFIAPEVVNYDEINFTT--DMWSIGVICYILLSG 420
>12672
          Length = 773

 Score = 44.3 bits (103), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 32/90 (35%), Positives = 46/90 (51%), Gaps = 5/90 (5%)
 Frame = +3

Query: 169 LAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGE----PNVS-YICSRYYR 223
           + Y++  G  HRDIK  N+LLD +    K+ DF +      GE     N S  I +  Y 
Sbjct: 30  IQYLNDNGHVHRDIKTANILLDSEYTA-KVGDFATVVSAPSGEGKTVQNASVVIGTAAYL 206

Query: 224 APELIFGATDYTSSIDVWSAGCVLAELLLG 253
           APE I    D ++ +D +S G VL E++ G
Sbjct: 207 APEAIH--FDVSTKLDSYSFGVVLLEVITG 290
>16708
          Length = 1397

 Score = 42.4 bits (98), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 42/158 (26%), Positives = 69/158 (43%), Gaps = 12/158 (7%)
 Frame = -1

Query: 60   KVIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKNRELQIMRKLDHCNIVRLRYFFYSS 119
            +V+G G FG VY+A+L  + E  A+K  +      +  L  +  L      R+   FY +
Sbjct: 1385 QVLGKGVFGKVYEARLLSTHEKAALKTSI----LCHHSLDEVEALG-----RIEGGFYLA 1233

Query: 120  GEKKDEVY------LNLVLD-YVPETVYRVARHYSRAKQTLPVIYVKLYMY-----QLFR 167
                  V       +N++L  Y    +  V  HY    + +P+ +    M      Q   
Sbjct: 1232 QMFGAWVTCLPFPKMNILLHFYEMGPLCNVYAHYK--NKEMPIRWSNPAMVCCIAGQXVC 1059

Query: 168  SLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAK 205
            +L +IH  G+ H D+K  N+L+D      KL D+G A+
Sbjct: 1058 ALEHIHELGVVHMDVKADNVLVDAH-GNCKLTDYGIAQ 948
>07291
          Length = 833

 Score = 40.4 bits (93), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 30/112 (26%), Positives = 51/112 (45%), Gaps = 7/112 (6%)
 Frame = +1

Query: 147 SRAKQTLPVIYVKLYMYQLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQ 206
           ++  + L V+ +  +  Q+   +AY+    + HR++  +N ++  D   L+L D+G    
Sbjct: 22  AKPSKMLTVVQLLDFGRQIADGMAYLQEVKVVHRNLAARNCIVTED-GRLQLSDYGVTGS 198

Query: 207 LVRGEPNVSYICSRY-------YRAPELIFGATDYTSSIDVWSAGCVLAELL 251
           L    P   Y            + APE I     ++S  DVW+ G VL ELL
Sbjct: 199 LF---PQSYYTADDSPARDLVKWMAPETI-DNFHFSSKSDVWAFGVVLWELL 342
>00638
          Length = 1595

 Score = 40.0 bits (92), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 15/39 (38%), Positives = 25/39 (64%)
 Frame = +2

Query: 146 YSRAKQTLPVIYVKLYMYQLFRSLAYIHSFGICHRDIKP 184
           + +  QT     ++ Y+Y+L ++L + HS GI HRD+KP
Sbjct: 386 FKQLYQTFTDYDIRFYLYELMKALDFCHSMGIMHRDVKP 502
>36481
          Length = 806

 Score = 39.7 bits (91), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 34/138 (24%), Positives = 60/138 (43%), Gaps = 11/138 (7%)
 Frame = +2

Query: 63  GNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKNR---ELQIMRKL-------DHCNIVRL 112
           G G+FG V Q K    G+ +A+K +    +++     E+ ++ KL        H  +  L
Sbjct: 389 GEGTFGKVVQCKDLLKGDDIALKIIKNVDKYREAAKLEINVLEKLREKDPHAKHMCVQML 568

Query: 113 RYFFYSSGEKKDEVYLNL-VLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFRSLAY 171
            +F Y          L L V D++ +  Y             P+  V+   YQL  ++ +
Sbjct: 569 DWFDYHGHVCISFHMLGLSVFDFLKDNSY----------GAYPIEQVRHISYQLCYAVNF 718

Query: 172 IHSFGICHRDIKPQNLLL 189
           +H   + H D+KP+N+L 
Sbjct: 719 LHENQLTHTDLKPENILF 772
>16003
          Length = 926

 Score = 39.3 bits (90), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 21/58 (36%), Positives = 33/58 (56%), Gaps = 2/58 (3%)
 Frame = -1

Query: 250 LLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMN--PNYTEFKFPQIKAHPWTKVF 305
           LL+  P  PGD+ +DQL +I  +LGTPT  +   +   P+Y +FK    +  P  ++F
Sbjct: 926 LLIRLPFLPGDTDLDQLGKIFNMLGTPTETEWPAVTSLPDYIQFK--HCQKQPLKEIF 759
>26009
          Length = 886

 Score = 38.1 bits (87), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 18/36 (50%), Positives = 24/36 (66%), Gaps = 1/36 (2%)
 Frame = +3

Query: 158 VKLYMYQLFRSLAYIHSFGICHRDIKPQN-LLLDPD 192
            K  M QL  +L ++HS  + HRDIKP+N L+L PD
Sbjct: 717 AKSVMKQLVSALDFMHSKQLVHRDIKPENVLILTPD 824
>25019
          Length = 730

 Score = 37.7 bits (86), Expect = 0.010,   Method: Compositional matrix adjust.
 Identities = 24/61 (39%), Positives = 31/61 (50%), Gaps = 1/61 (1%)
 Frame = +3

Query: 185 QNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRY-YRAPELIFGATDYTSSIDVWSA 243
           +N+LLD D  V KL DFG  K+ + G       C    Y APE I   T +  ++D WS 
Sbjct: 261 ENVLLDKDGHV-KLTDFGLCKEAITGTRVTHTFCGTIEYMAPE-ILTRTGHGKAVDWWSL 434

Query: 244 G 244
           G
Sbjct: 435 G 437
>21800
          Length = 855

 Score = 37.7 bits (86), Expect = 0.010,   Method: Compositional matrix adjust.
 Identities = 19/43 (44%), Positives = 27/43 (62%), Gaps = 1/43 (2%)
 Frame = +2

Query: 151 QTLPVIYVKLYMYQLFRSLAYIHS-FGICHRDIKPQNLLLDPD 192
           Q +PV  VKL + Q+   L Y+H+   I H DIKP+N+L+  D
Sbjct: 617 QGIPVHNVKLIIRQVLEGLNYLHAKCNIIHTDIKPENILICVD 745
>01106
          Length = 878

 Score = 37.7 bits (86), Expect = 0.010,   Method: Compositional matrix adjust.
 Identities = 18/48 (37%), Positives = 30/48 (62%), Gaps = 1/48 (2%)
 Frame = +3

Query: 151 QTLPVIYVKLYMYQLFRSLAYIHS-FGICHRDIKPQNLLLDPDTAVLK 197
           Q +P+  VKL + Q+   L+Y+H+   I H DIKP+N+L+  D   ++
Sbjct: 630 QGIPIHNVKLIIRQVLEGLSYMHAKCRIIHTDIKPENILICVDETYIR 773
>29360
          Length = 363

 Score = 35.8 bits (81), Expect = 0.030,   Method: Composition-based stats.
 Identities = 29/120 (24%), Positives = 57/120 (47%), Gaps = 8/120 (6%)
 Frame = +3

Query: 78  SGELVAIKKVLQDKRFKNR---ELQIMRKL-----DHCNIVRLRYFFYSSGEKKDEVYLN 129
           + E+VAIK +     +  +   E+ I+++L     D  N VR    F      + + +  
Sbjct: 24  TSEIVAIKILKNHPSYARQGQIEVSILQRLSQESADDYNFVRAFECF------QHKNHTC 185

Query: 130 LVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFRSLAYIHSFGICHRDIKPQNLLL 189
           LV + + + +Y   +      Q LP+ Y++    Q+  +L  +   G+ H D+KP+N++L
Sbjct: 186 LVFEMLEQNLYDFLKQ--NKFQPLPLKYIRPITQQVLTALRKLKQLGLIHADLKPENIML 359
>13078
          Length = 773

 Score = 35.4 bits (80), Expect = 0.039,   Method: Compositional matrix adjust.
 Identities = 13/42 (30%), Positives = 23/42 (54%)
 Frame = -1

Query: 234 YTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGT 275
           ++   DVWS GC++ EL  G  +F      + L  + ++LG+
Sbjct: 746 WSQPCDVWSIGCIMFELYTGYTLFQTHDNKEHLAMMERILGS 621
>02638
          Length = 1490

 Score = 35.0 bits (79), Expect = 0.060,   Method: Compositional matrix adjust.
 Identities = 17/51 (33%), Positives = 28/51 (54%)
 Frame = +1

Query: 222 YRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKV 272
           + APE++ G + Y  + DVWS GCV+ E+   +P +      + L  I K+
Sbjct: 34  FMAPEVLRGES-YGRACDVWSVGCVMIEMCTCRPPWNSHDISNHLALIFKI 183
>00486
          Length = 797

 Score = 33.9 bits (76), Expect = 0.12,   Method: Compositional matrix adjust.
 Identities = 16/50 (32%), Positives = 28/50 (56%)
 Frame = -2

Query: 222 YRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIK 271
           Y APE I   T +  ++D WS G ++ ++L G P F  ++    + +I+K
Sbjct: 760 YMAPE-ILTRTGHGKAVDWWSLGALMYDMLTGSPPFTAENRKKTIDKILK 614
>20152
          Length = 445

 Score = 33.5 bits (75), Expect = 0.15,   Method: Compositional matrix adjust.
 Identities = 22/86 (25%), Positives = 38/86 (44%), Gaps = 9/86 (10%)
 Frame = +1

Query: 225 PELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKV-------LGTPT 277
           PE++ G +    ++DVWS G +L  L++G+  F   +  + L  I+         +    
Sbjct: 1   PEILLGDSYDAPAVDVWSLGVILYMLVVGEAPFQEANDSETLTMIMDCRYQIPPHISHKC 180

Query: 278 REQIREM--NPNYTEFKFPQIKAHPW 301
           ++ I +M           P I AHPW
Sbjct: 181 QDLIEKMLQREPVDRASLPHILAHPW 258
>37602
          Length = 804

 Score = 33.1 bits (74), Expect = 0.20,   Method: Compositional matrix adjust.
 Identities = 17/38 (44%), Positives = 22/38 (57%)
 Frame = -1

Query: 164 QLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDF 201
           +  + L Y+H  G  HRDIK  N+LL  +  V KL DF
Sbjct: 195 ETLKGLHYLHRRGKMHRDIKGANILLTEEGDV-KLADF 85
>18481
          Length = 437

 Score = 32.0 bits (71), Expect = 0.44,   Method: Compositional matrix adjust.
 Identities = 18/45 (40%), Positives = 23/45 (51%), Gaps = 2/45 (4%)
 Frame = -1

Query: 164 QLFRSLAYIHSFGICHRDIKPQNLL--LDPDTAVLKLCDFGSAKQ 206
           QL   L +IH     HRD+KP N L  L      L + DFG +K+
Sbjct: 173 QLLSRLEFIHQKCFIHRDLKPDNFLMGLGRHCHRLYIIDFGLSKR 39
>35032
          Length = 465

 Score = 31.6 bits (70), Expect = 0.65,   Method: Compositional matrix adjust.
 Identities = 14/25 (56%), Positives = 15/25 (60%)
 Frame = +3

Query: 316 LCSRLLEYTPTARLTPLEACAHSFF 340
           L  RLL Y P+ RLTP  A AH F 
Sbjct: 150 LVKRLLNYDPSKRLTPXXALAHPFL 224
>38560
          Length = 479

 Score = 30.8 bits (68), Expect = 1.0,   Method: Compositional matrix adjust.
 Identities = 16/32 (50%), Positives = 18/32 (56%)
 Frame = -3

Query: 222 YRAPELIFGATDYTSSIDVWSAGCVLAELLLG 253
           Y APELI G     S  D+WS G +L  LL G
Sbjct: 387 YAAPELISGLEYLGSEADIWSMGVLLYALLCG 292
>19248
          Length = 973

 Score = 30.4 bits (67), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 20/88 (22%), Positives = 41/88 (46%)
 Frame = -3

Query: 6   RTTSFAESCKPVQQPSAFGSMKVSRDKDGSKVTTVVATPGQGPDRPQEVSYTDTKVIGNG 65
           +T++ A    PV+ P+ +GSM  S+D             G  P+ P E S++D +    G
Sbjct: 497 QTSAHAPQHYPVEDPAGYGSMHASKD-------------GNFPELPLESSHSDERGPCRG 357

Query: 66  SFGVVYQAKLCDSGELVAIKKVLQDKRF 93
           S  ++ +       +L A+  ++  +++
Sbjct: 356 SHLLMMETHT**WRKLGAVSTIIWPRKY 273
>32357
          Length = 625

 Score = 30.0 bits (66), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 16/37 (43%), Positives = 22/37 (59%)
 Frame = -2

Query: 56  YTDTKVIGNGSFGVVYQAKLCDSGELVAIKKVLQDKR 92
           Y   K IG+GSFG +Y      SGE VA+K  L++ +
Sbjct: 432 YRLMKKIGSGSFGEIYLGVHNTSGEEVAVKLELKNAK 322
>24241
          Length = 413

 Score = 30.0 bits (66), Expect = 1.8,   Method: Composition-based stats.
 Identities = 17/55 (30%), Positives = 30/55 (54%), Gaps = 10/55 (18%)
 Frame = -2

Query: 62  IGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKN----------RELQIMRKLDH 106
           IG G++GVVY+ +   +G  +A+KK+    R +           RE+ ++R+L H
Sbjct: 319 IGEGTYGVVYKCRHRATGRKLAMKKI----RLRGSEDGVPSSAIREIAMLRELRH 167
>19149
          Length = 454

 Score = 28.5 bits (62), Expect = 5.1,   Method: Compositional matrix adjust.
 Identities = 12/21 (57%), Positives = 15/21 (71%)
 Frame = -3

Query: 307 PRTPPEAIALCSRLLEYTPTA 327
           P+ P  A+ALCSRLL  TP +
Sbjct: 74  PKDPSSALALCSRLLVLTPNS 12
>32957
          Length = 645

 Score = 28.1 bits (61), Expect = 6.5,   Method: Compositional matrix adjust.
 Identities = 14/40 (35%), Positives = 21/40 (52%)
 Frame = +3

Query: 215 SYICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQ 254
           ++  +R Y APE +    +Y   +D W  G +L ELL  Q
Sbjct: 42  TFCGTREYMAPE-VHERKEYGKEVDWWGLGILLHELLAAQ 158
>26052
          Length = 562

 Score = 28.1 bits (61), Expect = 7.5,   Method: Compositional matrix adjust.
 Identities = 13/32 (40%), Positives = 20/32 (62%)
 Frame = -1

Query: 56  YTDTKVIGNGSFGVVYQAKLCDSGELVAIKKV 87
           Y   K++G GSFG V   +  D+GE +A+K +
Sbjct: 385 YLFXKLLGVGSFGKVMALQHKDTGETLAVKNI 290
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|13386054|ref|NP_080828.1| actin related protein 2/3
complex, subunit 4 [Mus musculus]
         (168 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

00913                                                                 293   3e-80
25196                                                                 142   6e-62
18222                                                                  28   2.4  
>00913
          Length = 1755

 Score =  293 bits (749), Expect = 3e-80,   Method: Compositional matrix adjust.
 Identities = 138/168 (82%), Positives = 156/168 (92%)
 Frame = -3

Query: 1    MTATLRPYLSAVRATLQAALCLENFSSQVVERHNKPEVEVRSSKELLLQPVTISRNEKEK 60
            M ATL+PYL+ V+ TL AA+C++NF SQ+VERHNKPEVEV+SSKELLL PV ISRNEKE+
Sbjct: 1513 MAATLKPYLNCVKETLTAAMCVQNFDSQMVERHNKPEVEVKSSKELLLTPVVISRNEKER 1334

Query: 61   VLIEGSINSVRVSIAVKQADEIEKILCHKFMRFMMMRAENFFILRRKPVEGYDISFLITN 120
            VLIE SINS+RVSIAVKQADEIE+ILCHKFMRFMMMRAENF +LRRKPVEGYDISFL+TN
Sbjct: 1333 VLIESSINSIRVSIAVKQADEIERILCHKFMRFMMMRAENFVVLRRKPVEGYDISFLVTN 1154

Query: 121  FHTEQMYKHKLVDFVIHFMEEIDKEISEMKLSVNARARIVAEEFLKNF 168
             HTEQM+KHKLVDF+I FMEEIDKEI+EMKL+VN+RARI AEEFLKNF
Sbjct: 1153 VHTEQMFKHKLVDFIIQFMEEIDKEINEMKLAVNSRARISAEEFLKNF 1010
>25196
          Length = 736

 Score =  142 bits (358), Expect(2) = 6e-62,   Method: Compositional matrix adjust.
 Identities = 68/79 (86%), Positives = 75/79 (94%)
 Frame = +2

Query: 28  QVVERHNKPEVEVRSSKELLLQPVTISRNEKEKVLIEGSINSVRVSIAVKQADEIEKILC 87
           ++VERHNKPEVEV+SSKELLL PV ISRNEKE+VLIE SINS+RVSIAVKQADEIE+ILC
Sbjct: 56  KMVERHNKPEVEVKSSKELLLTPVVISRNEKERVLIESSINSIRVSIAVKQADEIERILC 235

Query: 88  HKFMRFMMMRAENFFILRR 106
           HKFMRFMMMRAENF +LRR
Sbjct: 236 HKFMRFMMMRAENFVVLRR 292

 Score =  111 bits (278), Expect(2) = 6e-62,   Method: Compositional matrix adjust.
 Identities = 51/61 (83%), Positives = 57/61 (93%)
 Frame = +1

Query: 107 KPVEGYDISFLITNFHTEQMYKHKLVDFVIHFMEEIDKEISEMKLSVNARARIVAEEFLK 166
           KPVEGYDISFL+TN HTEQM+KHKLVDF+I FMEEIDKEI+EMKL+VN+RARI AEEFLK
Sbjct: 292 KPVEGYDISFLVTNVHTEQMFKHKLVDFIIQFMEEIDKEINEMKLAVNSRARISAEEFLK 471

Query: 167 N 167
            
Sbjct: 472 T 474
>18222
          Length = 402

 Score = 27.7 bits (60), Expect = 2.4,   Method: Compositional matrix adjust.
 Identities = 19/61 (31%), Positives = 30/61 (49%)
 Frame = -2

Query: 85  ILCHKFMRFMMMRAENFFILRRKPVEGYDISFLITNFHTEQMYKHKLVDFVIHFMEEIDK 144
           +LC K M F  M    F +L+      +  SF++ N       KH L+DFV +F E+++ 
Sbjct: 269 VLCCKIMGFNFM----F*VLKLNYTCIFIASFILKNI------KHSLIDFVTYFCEDMNG 120

Query: 145 E 145
            
Sbjct: 119 N 117
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6753658|ref|NP_034194.1| dynein cytoplasmic 1
intermediate chain 2 [Mus musculus]
         (612 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

20271                                                                 295   3e-80
14105                                                                 170   1e-42
12841                                                                 124   1e-28
07741                                                                  55   8e-08
20662                                                                  54   1e-07
08355                                                                  47   3e-05
03387                                                                  46   4e-05
13278                                                                  43   3e-04
02960                                                                  41   0.001
27475                                                                  35   0.13 
05393                                                                  34   0.19 
01598                                                                  33   0.24 
00432                                                                  32   0.52 
27465                                                                  32   0.60 
01768                                                                  32   1.1  
26107                                                                  30   1.9  
06996                                                                  30   2.0  
37180                                                                  30   2.6  
12140                                                                  30   2.7  
21219                                                                  30   3.6  
00561                                                                  30   3.6  
30429                                                                  29   4.4  
01805                                                                  29   5.5  
17602                                                                  28   7.4  
03395                                                                  28   7.9  
>20271
          Length = 567

 Score =  295 bits (756), Expect = 3e-80,   Method: Compositional matrix adjust.
 Identities = 138/189 (73%), Positives = 157/189 (83%)
 Frame = -1

Query: 356 HPVYCVNVVGTQNAHNLISISTDGKICSWSLDMLSHPQDSMELVHKQSKAVAVTSMSFPV 415
           HPVYC+ VVGTQNAHNLIS+S DGK+CSWSLDMLS PQDSMEL HKQSK+VA T  SF  
Sbjct: 567 HPVYCITVVGTQNAHNLISVSNDGKLCSWSLDMLSQPQDSMELQHKQSKSVAATCFSFLS 388

Query: 416 GDVNNFVVGSEEGSVYTACRHGSKAGISEMFEGHQGPITGIHCHAAVGAVDFSHLFVTSS 475
           GD NNF+VGSEE  VY+A RHGSKAGI+E +EGHQGPIT I  H A G +DFS  F+T+S
Sbjct: 387 GDANNFIVGSEECLVYSASRHGSKAGINEAYEGHQGPITAIDTHHAAGQIDFSPFFLTAS 208

Query: 476 FDWTVKLWTTKNNKPLYSFEDNSDYVYDVMWSPTHPALFACVDGMGRLDLWNLNNDTEVP 535
           FDWTVKLW  K  K + SFEDNSDYV DV WSPT+PALF+CVD MGRLDLW+LN++TEVP
Sbjct: 207 FDWTVKLWNIKEQKYVCSFEDNSDYVSDVQWSPTNPALFSCVDIMGRLDLWHLNHETEVP 28

Query: 536 TASISVEGN 544
           TAS+ V+GN
Sbjct: 27  TASVVVDGN 1
>14105
          Length = 429

 Score =  170 bits (431), Expect = 1e-42,   Method: Compositional matrix adjust.
 Identities = 76/111 (68%), Positives = 87/111 (78%)
 Frame = +3

Query: 482 LWTTKNNKPLYSFEDNSDYVYDVMWSPTHPALFACVDGMGRLDLWNLNNDTEVPTASISV 541
           LW+ K+ KPLYSFEDNSDYV DV WSP HPALFA VDG GRLDLWNLN DTEVPTASI V
Sbjct: 3   LWSLKDTKPLYSFEDNSDYVMDVAWSPVHPALFAAVDGSGRLDLWNLNQDTEVPTASIVV 182

Query: 542 EGNPALNRVRWTHSGREIAVGDSEGQIVIYDVGEQIAVPRNDEWARFGRTL 592
           +G PALNRV WT SG  + +GD  G++ +YDV E +A+P  DEW+RF  TL
Sbjct: 183 DGAPALNRVSWTPSGLHVTIGDESGKLYVYDVAEHLALPTRDEWSRFNATL 335
>12841
          Length = 1364

 Score =  124 bits (310), Expect = 1e-28,   Method: Compositional matrix adjust.
 Identities = 89/333 (26%), Positives = 145/333 (43%), Gaps = 28/333 (8%)
 Frame = +1

Query: 246 FDERWS------KHRVVSCLDWSSQYPELLVASYNNNEEAPHEPDGVALVWNMKYKKTTP 299
            D  WS      K R VSCL W+   P+L+   Y   +   ++  G+   W++K     P
Sbjct: 361 LDRLWSYVCPLTKGRNVSCLAWNKSNPDLVAVGYGQFD-FTNQKSGLICCWSLK-NPEYP 534

Query: 300 EYVFHCQSAVMSATFAKFHPNLVVGGTYSGQIVLWDNRSNKRTPVQRTPLSAAAHTHPVY 359
           E V+     V S  F+  + N++  G Y G + +++ RS    P+     +   H  PV+
Sbjct: 535 ERVYTSTHGVTSLDFSVANANILAAGYYDGGVAIYNVRSTSDEPILDNQETHGKHLGPVW 714

Query: 360 CVNVV------GTQNAHNLISISTDGKICSWSLDMLSHPQDSMELVH---------KQSK 404
            +  +      G + A  LISISTDG++  WS+       + M L           ++ K
Sbjct: 715 QIQWIEKERGSGEERAEVLISISTDGRVTQWSIRKGFESNNIMRLKKLPTRMAGKAREKK 894

Query: 405 AVAVTS-------MSFPVGDVNNFVVGSEEGSVYTACRHGSKAGISEMFEGHQGPITGIH 457
             A  S         F   D+N ++ G+EEG ++  C         E + GH  P+  I 
Sbjct: 895 GEAFISRHAGGLCFDFHSRDLNVYLAGTEEGYIH-KCSCSYNEQYLETYSGHTAPVYHIR 1071

Query: 458 CHAAVGAVDFSHLFVTSSFDWTVKLWTTKNNKPLYSFEDNSDYVYDVMWSPTHPALFACV 517
               V     S +F++ S DW+++LW      P+ +F  ++  V+DV WSP    +FACV
Sbjct: 1072WSPFV-----SDIFLSCSADWSIRLWHQDRTTPILTFHSSTKTVHDVCWSPRSSTVFACV 1236

Query: 518 DGMGRLDLWNLNNDTEVPTASISVEGNPALNRV 550
              G +++W+L   T     +I+      L  V
Sbjct: 1237H-EGAVEVWDLAQSTLDAVITITPTSGAKLTSV 1332
>07741
          Length = 2119

 Score = 55.1 bits (131), Expect = 8e-08,   Method: Compositional matrix adjust.
 Identities = 43/165 (26%), Positives = 76/165 (46%), Gaps = 17/165 (10%)
 Frame = +1

Query: 421 FVVGSEEGSVYTACRHGSKAGISEMFEGHQGPITGIHCHAAVGAVDFSH----LFVTSSF 476
           F+VG+EEG V+  C     +   +  + H         + AV  V ++H    ++ T S 
Sbjct: 157 FLVGTEEGKVH-VCSKAYTSHFIDTLDSH---------NMAVYKVAWNHYHPKIYATCSA 306

Query: 477 DWTVKLW-----------TTKNNKPLYSFEDNSDYVYDVMWSPTHPALFACVDGMGRLDL 525
           DW VK+W            + + KPL+SF+ N+  V DV W+P    +FA V   G++ +
Sbjct: 307 DWNVKIWENGGKPTDTGXDSLSRKPLFSFDLNNS-VGDVAWAPYSSTVFAAVTADGKVCV 483

Query: 526 WNLNNDTEVPTAS--ISVEGNPALNRVRWTHSGREIAVGDSEGQI 568
           ++L+ +   P     ++ +    L  + +  S   + VGD  G +
Sbjct: 484 YDLSVNKYEPLCEQMVAQKKKTKLTHIEFNPSYPILIVGDDRGNV 618

 Score = 29.6 bits (65), Expect = 3.7,   Method: Compositional matrix adjust.
 Identities = 20/81 (24%), Positives = 37/81 (45%), Gaps = 8/81 (9%)
 Frame = +1

Query: 501 VYDVMWSPTHPALFACVDGMGRLDLW-NLNNDTEVPTASI------SVEGNPALNRVRWT 553
           VY V W+  HP ++A       + +W N    T+    S+      S + N ++  V W 
Sbjct: 250 VYKVAWNHYHPKIYATCSADWNVKIWENGGKPTDTGXDSLSRKPLFSFDLNNSVGDVAWA 429

Query: 554 -HSGREIAVGDSEGQIVIYDV 573
            +S    A   ++G++ +YD+
Sbjct: 430 PYSSTVFAAVTADGKVCVYDL 492
>20662
          Length = 1220

 Score = 54.3 bits (129), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 40/131 (30%), Positives = 69/131 (52%), Gaps = 4/131 (3%)
 Frame = +2

Query: 466 DFSHLFVTSSFDWTVKLWTTKNNKPLYSFEDNSDYVYDVMWSPTHPALFACVDGMGRLDL 525
           D SH ++++S+D  +K+W T +   LY++  +SD V+DV   PT PALF      G++ L
Sbjct: 419 DXSH-YLSASYDHGIKVWNT-DLTSLYTYRAHSDIVWDVQCHPTEPALFLSCSQDGKIVL 592

Query: 526 WNLNND---TEVPTASISVEGNPALNRVRWTHSGREI-AVGDSEGQIVIYDVGEQIAVPR 581
           W++      T +P  S   +  P    V+W  + R + AVGD  G + + D+  ++ V +
Sbjct: 593 WDVRESKPATCLPKCSSGFK--PTC--VQWQPNARNMYAVGDEGGHVSVQDL--RMVVEK 754

Query: 582 NDEWARFGRTL 592
           N  +    R +
Sbjct: 755 NVSYQSHNRVV 787
>08355
          Length = 498

 Score = 46.6 bits (109), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 47/173 (27%), Positives = 71/173 (41%), Gaps = 16/173 (9%)
 Frame = -1

Query: 327 YSGQIVLWDNRSNKRTPVQRTPLSAAAHTHPVYCVNVV--GTQNAHNLISISTDGKICSW 384
           Y G + L++       PVQR       HT PV+ V      + N  N  SIS+DG+I  W
Sbjct: 495 YDGSVALFNTIEKHNNPVQRCTADNGKHTDPVWQVRWQKDDSDNNMNFFSISSDGRIVHW 316

Query: 385 SL---DMLSHPQDSMELVHKQSKAVAVTSMSFPVGDVNN-----------FVVGSEEGSV 430
           ++   +M+   QD ++L      A     +   V                F+VG+EEG +
Sbjct: 315 TIVKNEMIY--QDIIQLTIPGPPAEGPDGIRMEVTGCGTAFDFHKHKDYLFLVGTEEGKM 142

Query: 431 YTACRHGSKAGISEMFEGHQGPITGIHCHAAVGAVDFSHLFVTSSFDWTVKLW 483
           +      SKA  S  F G  G    +  +         +++ T S DW VK+W
Sbjct: 141 HVC----SKAYTSH-FIG-SGDAHNMAIYKVAWNRFHPNVYATCSADWNVKIW 1
>03387
          Length = 1891

 Score = 46.2 bits (108), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 61/262 (23%), Positives = 106/262 (40%), Gaps = 13/262 (4%)
 Frame = +1

Query: 309 VMSATFAKFHPNLVVGGTYSGQIVLWDNRSNKRTP---VQRTP-LSAAAHTHPVYCVNVV 364
           V  A +   +P ++   T S  ++++D   +   P    +  P L    H    Y ++  
Sbjct: 211 VNRARYMPQNPCIIATKTPSSDVLVFDYTKHPSKPDPSGECIPELRLKGHQKEGYGLSWN 390

Query: 365 GTQNAHNLISISTDGKICSWSLDMLSHPQDSMELVHKQSKAVAVTSMSFPVGDVNNFV-- 422
              N H L+S S D  IC W ++     Q    +V   +     TS+   V DV   +  
Sbjct: 391 PNLNGH-LLSASDDHTICLWDINST---QRESRVVDAHTIFTGHTSV---VEDVAWHLLH 549

Query: 423 ------VGSEEGSVYTACRHGSKAGISEMFEGHQGPITGIHCHAAVGAVDFSHLFVTSSF 476
                 V  ++  +    R  + +  S + + H   +    C +     +F  +  T S 
Sbjct: 550 ESLFGSVADDQKLMIWDTRSNTTSKPSHVVDAHTAEVN---CLSFNPYSEF--ILATGSA 714

Query: 477 DWTVKLWTTKNNK-PLYSFEDNSDYVYDVMWSPTHPALFACVDGMGRLDLWNLNNDTEVP 535
           D TV LW  +N K  L+SFE + D ++ V WSP +  + A      RL +W+L+   E  
Sbjct: 715 DKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLHVWDLSKIGEEQ 894

Query: 536 TASISVEGNPALNRVRWTHSGR 557
               + +G P L  +   H+ +
Sbjct: 895 LPEDAEDGPPELLFIHGGHTAK 960
>13278
          Length = 870

 Score = 43.1 bits (100), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 29/110 (26%), Positives = 51/110 (46%), Gaps = 4/110 (3%)
 Frame = +1

Query: 468 SHLFVTSSFDWTVKLWTTKNNKPLYSFEDNSDYVYDVMWSPTHPALFACVDGMGRLD--- 524
           S +  ++SFD TV+LW  +    L++   + + VY V +SP    L +     G  D   
Sbjct: 112 SLILASASFDSTVRLWEVERGLCLHTLTKHQEPVYSVAFSPDGKYLAS-----GSFDKCV 276

Query: 525 -LWNLNNDTEVPTASISVEGNPALNRVRWTHSGREIAVGDSEGQIVIYDV 573
            +WN+   + V     S +G   +  V W H G ++    S+G + + D+
Sbjct: 277 HIWNVQTGSLVH----SYKGTGGIFEVCWNHRGDKVGASASDGSVFVLDL 414
>02960
          Length = 1577

 Score = 41.2 bits (95), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 65/265 (24%), Positives = 100/265 (37%), Gaps = 30/265 (11%)
 Frame = +2

Query: 284 DGVALVWNMKYKKTTPEYVFHCQSAVMSATFAKFHPN--LVVGGTYSGQIVLWDNRSN-- 339
           D  ALVW  + +    +    C+    S       P+   +  G++   + LW    N  
Sbjct: 680 DQTALVWQWQRETNEVDCRLSCRGHAASVDCVAVSPDSQQMCTGSWDKMLKLWSTDCNVD 859

Query: 340 -----------------KRTPVQRTP-LSAAAHTHPVYCVNVVGTQNAHNLISISTDGKI 381
                            K T   R P L+ + H   V  V  +   + H +++ S D  +
Sbjct: 860 GDQSEDTERPSKKKKSAKSTTQTRVPVLTLSGHAEAVSAVRWL---DPHRVVTSSWDHSL 1030

Query: 382 CSWSLDMLSHPQDSMELVHKQSKAVAVTSMSFPVGDVNNFVVGSEEGSVYTA---CRHGS 438
             W L    H      L+ + SKAV   + S P+   +  + GS +  V      C  G 
Sbjct: 1031RLWDL----HTAQQTSLI-QGSKAVLDVAYS-PLS--HMLITGSADRHVRLVDPRCSEGE 1186

Query: 439 KAGISEMFEGHQGPITGIHCHAAVGAVDFS----HLFVTSSFDWTVKLWTTKNNKP-LYS 493
               +  F  H G +TG         VD+S    HLF++ S+D  +KLW T++ K  LY 
Sbjct: 1187TVKCA--FTSHTGWVTG---------VDWSPTREHLFLSGSYDNVLKLWDTRSPKATLYD 1333

Query: 494 FEDNSDYVYDVMWSPTHPALFACVD 518
              + D +  V WS     L   VD
Sbjct: 1334MNWHEDRILAVDWSIPELLLSGGVD 1408
>27475
          Length = 369

 Score = 34.7 bits (78), Expect = 0.13,   Method: Compositional matrix adjust.
 Identities = 27/78 (34%), Positives = 37/78 (47%), Gaps = 5/78 (6%)
 Frame = +2

Query: 446 FEGHQGPITGIHCHAAVGAVDFS----HLFVTSSFDWTVKLWTTKNNKP-LYSFEDNSDY 500
           F  H G +TG         VD+S    HLF++ S+D  +KLW T++ K  LY    + D 
Sbjct: 56  FTSHTGWVTG---------VDWSPTREHLFLSGSYDNVLKLWDTRSPKATLYDMNWHEDR 208

Query: 501 VYDVMWSPTHPALFACVD 518
           +  V WS     L   VD
Sbjct: 209 ILAVDWSIPELLLSGGVD 262
>05393
          Length = 904

 Score = 33.9 bits (76), Expect = 0.19,   Method: Compositional matrix adjust.
 Identities = 24/93 (25%), Positives = 42/93 (45%), Gaps = 7/93 (7%)
 Frame = +1

Query: 449 HQGPITGIHCHA-AVGAVDFSH----LFVTSSFDWTVKLWTTKNNKPLYSFEDNSDY--V 501
           H+ P+  +  H+  V  V  S     L +T+S D T+K+W  +++KP + F  N     +
Sbjct: 187 HEKPVFSVGAHSSCVTGVCLSSQIPGLMITTSEDKTMKVWDIQDDKPTHVFSRNLKMKEL 366

Query: 502 YDVMWSPTHPALFACVDGMGRLDLWNLNNDTEV 534
           +     P  P +FA   G     +W++     V
Sbjct: 367 HCTGCCPEAPFVFAVGGGRREPKVWDIRESAAV 465
>01598
          Length = 1545

 Score = 33.5 bits (75), Expect = 0.24,   Method: Compositional matrix adjust.
 Identities = 29/109 (26%), Positives = 46/109 (42%), Gaps = 3/109 (2%)
 Frame = +1

Query: 468 SHLFVTSSFDWTVKLWTTKNNKPLYSFEDNSDYVYDVMWSPTHPALFACVDGMGRLDLWN 527
           S    T + D  V LW  +  + + S      +VY V  SP  P   A   G   +  WN
Sbjct: 415 SKTLCTFAQDRQVVLWDLETMEAVASMATLGGHVYCVRTSPIDPGRVAVGVGDSMIRTWN 594

Query: 528 LNNDTEVPTASISVEG-NPALNRVRWTHSGRE--IAVGDSEGQIVIYDV 573
           ++N T     +   +G    +  V W H  +E  +  G  +G+I ++DV
Sbjct: 595 MSNKTNPYDVTTLWQGIKSKVTAVAW-HPTKEGWLGFGTDDGRIGVFDV 738

 Score = 30.4 bits (67), Expect = 2.5,   Method: Compositional matrix adjust.
 Identities = 71/291 (24%), Positives = 105/291 (36%), Gaps = 40/291 (13%)
 Frame = +1

Query: 284 DGVALVWNMKYKKTTPEYVFHCQSAVMSATFAKFHP---NLVVGGTYSGQIVLWDNRSNK 340
           D +   WNM  K    +     Q      T   +HP     +  GT  G+I ++D  S+K
Sbjct: 571 DSMIRTWNMSNKTNPYDVTTLWQGIKSKVTAVAWHPTKEGWLGFGTDDGRIGVFDVLSHK 750

Query: 341 RTPVQRTPLSAAAHTHPVYCVNVVGTQ----NAHNLISISTDGKICSWSLDMLSHPQ--- 393
              +  T     A+   V C            + +L S+  D KI   S  +LS  +   
Sbjct: 751 MPTLSNTFHHRTAY---VVCWGPASLSPTDGKSFSLYSVG-DCKILEHSSAVLSRGEKKA 918

Query: 394 DSMELVHK-------QSKAVAVTSMSFPVGDVNNFVVGSEEGSVYT----------ACRH 436
           +++++  K       Q K +  T +S+   D N   VG++EGSVY           A R 
Sbjct: 919 NAIDITQKIGAVNSDQVKGLKATELSWSP-DQNAAAVGTDEGSVYVVTIQDLKIVAAIRT 1095

Query: 437 GSKAGISEMFEGH-----QGPITGIHCH--AAVG------AVDFSHLFVTSSFDWTVKLW 483
             K  +      H     Q P     CH  AA G       VD + +F     D    L 
Sbjct: 1096QQK--LINCVRWHPRLTDQSPAGSPCCHWLAAAGNDQVIHVVDLASVFAEREGDKETSLI 1269

Query: 484 TTKNNKPLYSFEDNSDYVYDVMWSPTHPALFACVDGMGRLDLWNLNNDTEV 534
            T     L     +S  V D+ WSP H A    V       +W++   T +
Sbjct: 1270LTS----LRELSGHSQRVTDMSWSPHHDARLVSVGYDAEAFVWDVQKGTAL 1410
>00432
          Length = 1557

 Score = 32.3 bits (72), Expect = 0.52,   Method: Compositional matrix adjust.
 Identities = 16/46 (34%), Positives = 23/46 (50%)
 Frame = -1

Query: 179 PHELTEEEKQQILHSEEFLSFFDHSTRIVERALSEQINIFFDYSGR 224
           PH LT + +Q   H E+F + F   TRI    L +  + FF +  R
Sbjct: 300 PHALTNQFRQFRFHREKFFTQFIGRTRIFHAILRQFFHAFFGFPNR 163
>27465
          Length = 658

 Score = 32.3 bits (72), Expect = 0.60,   Method: Compositional matrix adjust.
 Identities = 25/97 (25%), Positives = 47/97 (48%), Gaps = 6/97 (6%)
 Frame = -1

Query: 419 NNFVVGSEEGSVYTACRHGSKAGISEM--FEGHQGPITGIHCHAAVGAVDFSHLF----V 472
           ++F+ GS + +    C+    A   E+   EGH+           V A+ F++ F    +
Sbjct: 322 SSFITGSYDRT----CKIWDTASAEELHTLEGHRN---------VVYAIAFNNPFGDKVI 182

Query: 473 TSSFDWTVKLWTTKNNKPLYSFEDNSDYVYDVMWSPT 509
           T SFD T KLW+T + K  ++   ++  +  V ++P+
Sbjct: 181 TGSFDKTCKLWSTADGKCYHTLRGHTAEIVCVSFNPS 71
>01768
          Length = 1424

 Score = 31.6 bits (70), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 24/93 (25%), Positives = 43/93 (46%), Gaps = 2/93 (2%)
 Frame = +3

Query: 483 WTTKNNKPLYSFEDNSDYVYDVMWSPTHPALFACVDGMGRLDLWNLNND-TEVPTASISV 541
           WTT+ +    S+  ++D V DV WSP    +FA       L +WN     ++    ++  
Sbjct: 804 WTTEKS----SYAAHTDSVEDVQWSPNEGNVFASCSVDRTLRIWNTQQKPSKANVLTVPE 971

Query: 542 EGNPALNRVRWTHSGRE-IAVGDSEGQIVIYDV 573
             +  +N + W    +  +A G  +G I I+D+
Sbjct: 972 AHSRDINVINWNPIEKHLLASGGDDGIIKIWDL 1070

 Score = 28.5 bits (62), Expect = 7.3,   Method: Compositional matrix adjust.
 Identities = 27/120 (22%), Positives = 51/120 (42%), Gaps = 17/120 (14%)
 Frame = +3

Query: 427 EGSVYTAC------------RHGSKAGISEMFEGHQGPITGIHCHAAVGAVDFSHLFVTS 474
           EG+V+ +C            +  SKA +  + E H   I  I+ +         HL  + 
Sbjct: 873 EGNVFASCSVDRTLRIWNTQQKPSKANVLTVPEAHSRDINVINWNPIE-----KHLLASG 1037

Query: 475 SFDWTVKLWTTK--NNKPL---YSFEDNSDYVYDVMWSPTHPALFACVDGMGRLDLWNLN 529
             D  +K+W  +   NKP+    SF+ +S  V  + W+P   ++ A      ++ +W+ +
Sbjct: 1038GDDGIIKIWDLRMFRNKPVSAQASFKLHSQPVTSLEWNPQDSSVLAASGEDDQITIWDFS 1217
>26107
          Length = 1338

 Score = 30.4 bits (67), Expect = 1.9,   Method: Compositional matrix adjust.
 Identities = 24/95 (25%), Positives = 36/95 (37%), Gaps = 1/95 (1%)
 Frame = -3

Query: 248  ERWSKHR-VVSCLDWSSQYPELLVASYNNNEEAPHEPDGVALVWNMKYKKTTPEYVFHCQ 306
             RW  H   V    W S   + L AS           D    +W+++       ++ H +
Sbjct: 1105 HRWXAHNNAVFDYSWISNDSQCLTAS----------GDQTVALWDVETTTKVTTFIGH-K 959

Query: 307  SAVMSATFAKFHPNLVVGGTYSGQIVLWDNRSNKR 341
             +V S       P     G   G I+LWD+R NK+
Sbjct: 958  CSVRSVASCPSSPAQCASGARDGHIMLWDSRVNKK 854
>06996
          Length = 1826

 Score = 30.4 bits (67), Expect = 2.0,   Method: Compositional matrix adjust.
 Identities = 24/88 (27%), Positives = 40/88 (45%)
 Frame = -3

Query: 382  CSWSLDMLSHPQDSMELVHKQSKAVAVTSMSFPVGDVNNFVVGSEEGSVYTACRHGSKAG 441
             +WS++  S    SME++H    +V+++  S PV     FVVG  +   YT  +H +   
Sbjct: 1818 LNWSIE-FSSDLHSMEIIHHFFSSVSISPFSVPV-----FVVG--QPIPYTDLKHKTNTY 1663

Query: 442  ISEMFEGHQGPITGIHCHAAVGAVDFSH 469
              ++F       T    H  +  + FSH
Sbjct: 1662 AKDLFRKEWDKQTDYKLH-EISPILFSH 1582
>37180
          Length = 681

 Score = 30.0 bits (66), Expect = 2.6,   Method: Compositional matrix adjust.
 Identities = 28/112 (25%), Positives = 47/112 (41%), Gaps = 6/112 (5%)
 Frame = +1

Query: 444 EMFEGHQGPITGIHCHAAVGAVDFSHLFVTSSFDWTVKLWTTKNNKPLYSFEDNSDYVYD 503
            +  GH   ++ +H H          L VTSS D T +LW  +++  L +       V+ 
Sbjct: 1   NVLNGHDQELSDVHAHPT------QRLVVTSSKDMTFRLWDFRDSALLVN-------VFQ 141

Query: 504 VMWSPTHPALFACVDGM------GRLDLWNLNNDTEVPTASISVEGNPALNR 549
               P   A+FA  D +        + +W++ N    P A+I  +   A+NR
Sbjct: 142 GHTQPVTSAVFASGDKVVSGSDDRTVRVWDMRN-MRSPIATIRTDS--AVNR 288
>12140
          Length = 727

 Score = 30.0 bits (66), Expect = 2.7,   Method: Compositional matrix adjust.
 Identities = 24/107 (22%), Positives = 49/107 (45%), Gaps = 6/107 (5%)
 Frame = +2

Query: 471 FVTSSFDWTVKLWTTKNNKPL--YSFEDNSDYVYDVMWSPT----HPALFACVDGMGRLD 524
           FV+   D  VK+W       +     E +SD+V DV W+P+       + +C     R+ 
Sbjct: 269 FVSGGCDNLVKIWREDETGWVEDQKLEGHSDWVRDVAWAPSIGLPRNVIASCSQDC-RVI 445

Query: 525 LWNLNNDTEVPTASISVEGNPALNRVRWTHSGREIAVGDSEGQIVIY 571
           +W  +  +   T+ I  + +  +  V W+ +G  +AV   + ++ ++
Sbjct: 446 IWTNDGSSNQWTSRILNKFSDVVWHVSWSVTGNILAVSGGDNKVTLW 586
>21219
          Length = 874

 Score = 29.6 bits (65), Expect = 3.6,   Method: Compositional matrix adjust.
 Identities = 19/47 (40%), Positives = 25/47 (53%)
 Frame = -3

Query: 489 KPLYSFEDNSDYVYDVMWSPTHPALFACVDGMGRLDLWNLNNDTEVP 535
           KPL     N  Y YDVM+S THP  F   + MG + ++  +   EVP
Sbjct: 143 KPL-----NHAYAYDVMFSHTHPYGF---NTMGIMGVYASSAKPEVP 27
>00561
          Length = 1003

 Score = 29.6 bits (65), Expect = 3.6,   Method: Compositional matrix adjust.
 Identities = 36/137 (26%), Positives = 59/137 (43%), Gaps = 4/137 (2%)
 Frame = -3

Query: 443 SEMFEGHQGPITGIHCHAAVGAVDFSHLFVTSSFDWTVKLWTTKNNKPLYSFED-NSDYV 501
           +  FEGH   +  +   A       +   V+ S D T+KLW T         ED ++D+V
Sbjct: 761 TRRFEGHTKDVLSVAFSAD------NRQIVSGSRDKTIKLWNTLAECKFTIQEDGHTDWV 600

Query: 502 YDVMWSPTH--PALFACVDGMGR-LDLWNLNNDTEVPTASISVEGNPALNRVRWTHSGRE 558
             V +SP H  P + +C  G  R + +WNL N       +     N  LN V  +  G  
Sbjct: 599 SCVRFSPNHSNPIIVSC--GWDRTVKVWNLAN---CKLKNNHHGHNGYLNTVTVSPDGSL 435

Query: 559 IAVGDSEGQIVIYDVGE 575
              G  + + +++D+ +
Sbjct: 434 CTSGGKDSKALLWDLND 384
>30429
          Length = 674

 Score = 29.3 bits (64), Expect = 4.4,   Method: Compositional matrix adjust.
 Identities = 15/49 (30%), Positives = 24/49 (48%), Gaps = 3/49 (6%)
 Frame = -2

Query: 470 LFVTSSFDWTVKLWTTKNNKPLY---SFEDNSDYVYDVMWSPTHPALFA 515
           + V   FDW +K +   N +PL+   SF D + +V+  +     P L A
Sbjct: 592 VLVKKCFDWKLKQFNNNNKRPLFHHNSFHDGNSHVWLCLCPSPLPNLIA 446
>01805
          Length = 2124

 Score = 29.3 bits (64), Expect = 5.5,   Method: Compositional matrix adjust.
 Identities = 17/54 (31%), Positives = 30/54 (55%), Gaps = 5/54 (9%)
 Frame = -1

Query: 449 HQGPITGIHCHAA-VGAVDFSH----LFVTSSFDWTVKLWTTKNNKPLYSFEDN 497
           H+ P+  +  H++ V  V  S     L +T+S D T+K+W  +++KP + F  N
Sbjct: 222 HEKPVFSVGAHSSCVTGVCLSSQIPGLMITTSEDKTMKVWDIQDDKPTHVFSRN 61
>17602
          Length = 481

 Score = 28.5 bits (62), Expect = 7.4,   Method: Composition-based stats.
 Identities = 21/81 (25%), Positives = 37/81 (45%), Gaps = 1/81 (1%)
 Frame = +3

Query: 448 GHQGPITGIHCHAAVGAVDFSHLFVTSSFDWTVKLWTTKNNKPLYSF-EDNSDYVYDVMW 506
            H  P+T +H +          L V+SS+D   ++W T + + L +  +D++  V  V +
Sbjct: 48  AHSDPVTAVHFNRD------GSLIVSSSYDGLCRIWDTASGQCLXTLIDDDNPPVSFVKF 209

Query: 507 SPTHPALFACVDGMGRLDLWN 527
           SP    + A       L LW+
Sbjct: 210 SPNGKYILAATLD-NTLKLWD 269
>03395
          Length = 2795

 Score = 28.5 bits (62), Expect = 7.9,   Method: Compositional matrix adjust.
 Identities = 38/165 (23%), Positives = 60/165 (36%), Gaps = 3/165 (1%)
 Frame = +2

Query: 322 VVGGTYSGQIVLWDNRSNKRTPVQRTPLSAAAHTHPVYCVNVVGTQNAHNLISISTDGKI 381
           +V G   GQ+ +WD   +  T   R  L A    H      +    N    +S STDG  
Sbjct: 41  LVSGGGEGQVRVWDIVKDMLTGKTRGDLVANMKEHKGKVTAIQIHTNDRCCVSASTDGST 220

Query: 382 CSWSLDMLSHPQDSMELVHKQSKAVAVTSMSFPVGDVNNFVVGSEEGSVYTACRHGSKAG 441
             W  D++++ +  + L +   K V      F   D++    G++    Y     G   G
Sbjct: 221 IIW--DLITNTRSQIVLANTLFKCVC-----FGGKDLHILTSGTDHKIGYWEVGDG---G 370

Query: 442 ISEMFEGHQGPITGIHCHAAVGAVDF---SHLFVTSSFDWTVKLW 483
           +    EG Q          A+  +D        +T   D  +KLW
Sbjct: 371 LLRELEGSQ--------TGAINTIDIDRDGQTILTGGEDSLLKLW 481
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|113866024|ref|NP_077776.2| RAB5C, member RAS oncogene
family [Mus musculus]
         (216 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

33374                                                                 228   5e-80
08428                                                                 192   1e-49
01095                                                                 170   4e-43
34468                                                                 127   3e-30
26083                                                                 124   2e-29
29380                                                                 114   3e-26
14456                                                                 112   1e-25
17511                                                                 111   2e-25
07580                                                                  87   5e-22
07465                                                                  97   5e-21
33794                                                                  97   5e-21
01972                                                                  77   4e-19
05468                                                                  90   8e-19
14119                                                                  87   5e-18
26536                                                                  86   1e-17
11257                                                                  86   1e-17
13750                                                                  85   3e-17
25618                                                                  84   4e-17
13901                                                                  80   4e-16
33380                                                                  80   5e-16
01398                                                                  80   6e-16
32723                                                                  79   2e-15
19006                                                                  78   2e-15
30760                                                                  78   3e-15
34359                                                                  74   4e-14
12339                                                                  74   6e-14
09204                                                                  72   2e-13
35581                                                                  70   6e-13
13745                                                                  70   7e-13
00858                                                                  63   7e-11
11728                                                                  63   8e-11
27191                                                                  59   1e-09
10708                                                                  39   9e-09
34597                                                                  55   2e-08
14775                                                                  54   4e-08
19656                                                                  52   3e-07
00552                                                                  47   7e-06
31291                                                                  46   9e-06
10862                                                                  42   2e-04
08153                                                                  42   2e-04
09827                                                                  40   9e-04
18509                                                                  35   0.017
06994                                                                  34   0.040
33605                                                                  32   0.15 
34156                                                                  31   0.37 
30516                                                                  28   2.8  
25991                                                                  27   9.2  
>33374
          Length = 489

 Score =  228 bits (582), Expect(2) = 5e-80,   Method: Compositional matrix adjust.
 Identities = 108/119 (90%), Positives = 114/119 (95%)
 Frame = +1

Query: 56  AAFLTQTVCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNTDTFARAKNW 115
           + FLTQTVCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITN DTF RAK W
Sbjct: 133 SCFLTQTVCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNQDTFGRAKTW 312

Query: 116 VKELQRQASPNIVIALAGNKADLASKRAVEFQEAQAYADDNSLLFMETSAKTAMNVNEI 174
           VKELQRQASPNIVIALAGNKADLA+KR VEF+EAQAYA++NSLLFMETSAKTAMNVN+I
Sbjct: 313 VKELQRQASPNIVIALAGNKADLANKRMVEFEEAQAYAEENSLLFMETSAKTAMNVNDI 489

 Score = 86.7 bits (213), Expect(2) = 5e-80,   Method: Compositional matrix adjust.
 Identities = 41/41 (100%), Positives = 41/41 (100%)
 Frame = +2

Query: 18 KICQFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAF 58
          KICQFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAF
Sbjct: 20 KICQFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAF 142
>08428
          Length = 1109

 Score =  192 bits (487), Expect = 1e-49,   Method: Compositional matrix adjust.
 Identities = 88/164 (53%), Positives = 121/164 (73%)
 Frame = -3

Query: 23   KLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQTVCLDDTTVKFEIWDTAGQER 82
            K+ LLG+S VGKSS+VLRFV G +   QESTIGA+F+++++ +D    +F+IWDTAGQE+
Sbjct: 1065 KVCLLGDSGVGKSSIVLRFVTGSYRPSQESTIGASFMSKSLVVDGAGYRFQIWDTAGQEK 886

Query: 83   YHSLAPMYYRGAQAAIVVYDITNTDTFARAKNWVKELQRQASPNIVIALAGNKADLASKR 142
            + +LAPMYYRGA AA++VYD+T   TF   K+W++EL+    PNIV+A+AGNK DL   R
Sbjct: 885  FRALAPMYYRGAAAAVIVYDVTRPRTFKSVKSWIQELRSFGPPNIVLAIAGNKCDLEELR 706

Query: 143  AVEFQEAQAYADDNSLLFMETSAKTAMNVNEIFMAIAKKLPKNE 186
             V  ++AQ YA   S +F ETSA TA+NV E+F  +A++LP  E
Sbjct: 705  EVVEKDAQEYASSISAIFGETSAMTAVNVEEMFTELARQLPPEE 574
>01095
          Length = 1745

 Score =  170 bits (430), Expect = 4e-43,   Method: Compositional matrix adjust.
 Identities = 87/117 (74%), Positives = 96/117 (82%), Gaps = 1/117 (0%)
 Frame = -1

Query: 99   VVYDITNTDTFARAKNWVKELQRQASPNIVIALAGNKADLASKRAVEFQEAQAYADDNSL 158
            VVYDITN DTF RAK WVKELQRQASPNIVIALAGNKADLA+KR VEF+EAQAYA++NSL
Sbjct: 1745 VVYDITNQDTFGRAKTWVKELQRQASPNIVIALAGNKADLANKRMVEFEEAQAYAEENSL 1566

Query: 159  LFMETSAKTAMNVNEIFMAIAKKLPKNEPQNAAGAPGRTRGVDL-QESNPASRSQCC 214
            LFMETSAKTAMNVN+IF+AIAKKLPKNE     G+  R +GV L  E +  S   CC
Sbjct: 1565 LFMETSAKTAMNVNDIFLAIAKKLPKNE--GGGGSQPRQQGVRLNNEQSQQSEGGCC 1401
>34468
          Length = 1502

 Score =  127 bits (320), Expect = 3e-30,   Method: Compositional matrix adjust.
 Identities = 71/190 (37%), Positives = 106/190 (55%), Gaps = 9/190 (4%)
 Frame = +1

Query: 22  FKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQTVCLDDTTVKFEIWDTAGQE 81
           FK++++G+S VGK+ L  RF  G+F +  E+TIG  F  +++ +D   +K ++WDTAGQE
Sbjct: 496 FKIIVIGDSNVGKTCLTYRFCLGKFPDKTEATIGVDFREKSIQVDSEHLKLQLWDTAGQE 675

Query: 82  RYH-SLAPMYYRGAQAAIVVYDITNTDTFARAKNWVKELQRQ-ASPNIVIALAGNKADLA 139
           R+  S+   YYR   A + VYD+T   +F     W++E  R   +  I   L GNK D+ 
Sbjct: 676 RFRKSMVQHYYRNVHAVVFVYDMTKMSSFENMPAWIEECDRHNLTKYIPRILVGNKCDVV 855

Query: 140 SKRAVEFQEAQAYADDNSLLFMETSAK---TAMNVNEIFMAIAKKLPKNEPQNAAG---- 192
            + AV    AQ +AD +++   ETSAK    A +V+ IFM +A KL  ++P   A     
Sbjct: 856 ERIAVNTNLAQKFADAHNMPLFETSAKDDEKANHVDAIFMTVAHKLKXSKPMMPAHLSEM 1035

Query: 193 APGRTRGVDL 202
            PG     DL
Sbjct: 1036VPGDVSHGDL 1065
>26083
          Length = 432

 Score =  124 bits (312), Expect = 2e-29,   Method: Compositional matrix adjust.
 Identities = 52/115 (45%), Positives = 81/115 (70%)
 Frame = +1

Query: 21  QFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQTVCLDDTTVKFEIWDTAGQ 80
           +FKLV LGE +VGK+SL+ RF+   F    ++TIG  FL++T+ L+D T++ ++WDTAGQ
Sbjct: 76  KFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTIRLQLWDTAGQ 255

Query: 81  ERYHSLAPMYYRGAQAAIVVYDITNTDTFARAKNWVKELQRQASPNIVIALAGNK 135
           ER+ SL P Y R +  A+VVYDITN ++F +   W+ +++ +   +++I L GNK
Sbjct: 256 ERFRSLIPSYIRDSSVAVVVYDITNANSFHQTSKWIDDVRTERGSDVIIMLVGNK 420
>29380
          Length = 853

 Score =  114 bits (285), Expect = 3e-26,   Method: Compositional matrix adjust.
 Identities = 62/122 (50%), Positives = 85/122 (69%), Gaps = 2/122 (1%)
 Frame = -2

Query: 94  AQAAIVVYDITNTDTFARAKNWVKELQRQASPNIVIALAGNKADLASK-RAVEFQEAQAY 152
           A AAI+VYD+   DTF+RA  WVKEL++Q + +++I LAGNK DLA++ RAV F++AQ++
Sbjct: 852 ASAAIIVYDVNIADTFSRALAWVKELRQQNTESVLIILAGNKVDLATQHRAVSFEDAQSF 673

Query: 153 ADDNSLLFMETSAKTAMNVNEIFMAIAKKLPKNEPQNAAGAPGRTRGVDL-QESNPASRS 211
           A +N LLF E SAKT M VNEIFM +A +L + E   +     R RGV L +E+  AS  
Sbjct: 672 ARENGLLFAEVSAKTGMAVNEIFMTLANQLIQQEIDGS-----RNRGVTLNRENGEASGC 508

Query: 212 QC 213
           +C
Sbjct: 507 KC 502
>14456
          Length = 1867

 Score =  112 bits (279), Expect = 1e-25,   Method: Compositional matrix adjust.
 Identities = 74/197 (37%), Positives = 102/197 (51%), Gaps = 9/197 (4%)
 Frame = -1

Query: 27   LGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQTVCLDDTTVKFEIWDTAGQERYHSL 86
            L +  VGKSSL+ RFV  +F      TIG  FL + V +DD T   +IWDTAGQER+ SL
Sbjct: 1123 LKQGGVGKSSLMNRFVSNKFDAQSFHTIGVEFLNKDVVVDDETYTMQIWDTAGQERFKSL 944

Query: 87   APMYYRGAQAAIVVYDITNTDTFARAKNWVKELQRQAS-------PNIVIALAGNKADLA 139
               +YRGA   ++ + + +  +F     W KE    A        P +V+   GNK D+ 
Sbjct: 943  RTPFYRGADCCLLTFSVDSMQSFRNLSMWRKEFLYYADIQDGVTFPFVVL---GNKIDVE 773

Query: 140  SKRAVEFQEAQAYADDNS-LLFMETSAKTAMNVNEIFMAIAKKLPKNEPQN-AAGAPGRT 197
              R V  +EA+++   NS   + ETSAK A NV + F+A  ++L + E Q     A G T
Sbjct: 772  G-RQVTNEEARSWCTANSNAPYFETSAKDATNVEKAFLAAVQRLREVEDQQEVKTAHGNT 596

Query: 198  RGVDLQESNPASRSQCC 214
              VDL  +     S CC
Sbjct: 595  --VDLNRAARGKSSSCC 551
>17511
          Length = 483

 Score =  111 bits (278), Expect = 2e-25,   Method: Compositional matrix adjust.
 Identities = 54/121 (44%), Positives = 77/121 (63%), Gaps = 4/121 (3%)
 Frame = -3

Query: 22  FKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQTVCLDDTTVKFEIWDTAGQE 81
            K+++LG+S VGK+SL+ ++V  +F    ++TIGA FLT+ V +DD  V  +IWDTAGQE
Sbjct: 364 LKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQIWDTAGQE 185

Query: 82  RYHSLAPMYYRGAQAAIVVYDITNTDTFARAKNWVKELQRQASP----NIVIALAGNKAD 137
           R+ SL   +YRGA   ++V+D+T  +TF    +W  E   QASP    N    + GNK D
Sbjct: 184 RFQSLGVAFYRGADCCVLVFDVTMPNTFRSLDSWRDEFLIQASPRDPENFPFVVIGNKID 5

Query: 138 L 138
           L
Sbjct: 4   L 2
>07580
          Length = 921

 Score = 86.7 bits (213), Expect(2) = 5e-22,   Method: Compositional matrix adjust.
 Identities = 53/154 (34%), Positives = 82/154 (53%), Gaps = 5/154 (3%)
 Frame = +3

Query: 43  KGQFHEYQESTIGAAFLTQTVCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYD 102
           KG F E  + TI  ++  Q V +D      EI DTAG E++ ++  +Y +  Q  ++ Y 
Sbjct: 126 KGIFVEKYDPTIEDSYRKQ-VEVDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFLLAYS 302

Query: 103 ITNTDTFARAKNWVKELQRQA-----SPNIVIALAGNKADLASKRAVEFQEAQAYADDNS 157
           IT   TF    N ++EL+ Q      + ++ + L GNK DL  +R V   + Q  A   S
Sbjct: 303 ITAQSTF----NDLQELREQILRVKDTDDVPMLLVGNKCDLEDERVVGKDQGQGLARSFS 470

Query: 158 LLFMETSAKTAMNVNEIFMAIAKKLPKNEPQNAA 191
             F+ETSAK  +NVNEIFM + +++ K  P+ + 
Sbjct: 471 CAFLETSAKARINVNEIFMDLVRQINKKSPEQSG 572

 Score = 33.9 bits (76), Expect(2) = 5e-22,   Method: Compositional matrix adjust.
 Identities = 14/26 (53%), Positives = 21/26 (80%)
 Frame = +2

Query: 21 QFKLVLLGESAVGKSSLVLRFVKGQF 46
          ++KLV+LG   VGKS+L ++FV+G F
Sbjct: 59 EYKLVVLGSGGVGKSALTVQFVQGDF 136
>07465
          Length = 1103

 Score = 97.1 bits (240), Expect = 5e-21,   Method: Compositional matrix adjust.
 Identities = 50/147 (34%), Positives = 81/147 (55%)
 Frame = +3

Query: 35  SSLVLRFVKGQFHEYQESTIGAAFLTQTVCLDDTTVKFEIWDTAGQERYHSLAPMYYRGA 94
           SS++ R+ KG F +  + TIG  FL + + +    V+  +WDTAGQE + ++   YYRGA
Sbjct: 240 SSMIQRYCKGIFTKDYKKTIGVDFLERQIEVGGEDVRLMLWDTAGQEEFDAITKAYYRGA 419

Query: 95  QAAIVVYDITNTDTFARAKNWVKELQRQASPNIVIALAGNKADLASKRAVEFQEAQAYAD 154
           QA ++ +   + D+F   + W ++++ +    I + +  NK DL     V  +EA+  A 
Sbjct: 420 QACVLAFSTVDRDSFEALETWKRKVEDEVGE-IGMVIVQNKIDLIDDAVVRPEEAENLAK 596

Query: 155 DNSLLFMETSAKTAMNVNEIFMAIAKK 181
              L F  TS K  MNV+E+F  +A K
Sbjct: 597 KLRLRFYRTSVKENMNVDEVFRYLADK 677
>33794
          Length = 779

 Score = 97.1 bits (240), Expect = 5e-21,   Method: Compositional matrix adjust.
 Identities = 50/125 (40%), Positives = 72/125 (57%)
 Frame = -1

Query: 56  AAFLTQTVCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNTDTFARAKNW 115
            A+ T T+ L+   VK +IWDT+GQ R+ ++   Y RGAQ  I+VYDITN  +F     W
Sbjct: 692 VAYKTTTILLEGKRVKLQIWDTSGQGRFCTIIRSYSRGAQGIILVYDITNKWSFDGIDRW 513

Query: 116 VKELQRQASPNIVIALAGNKADLASKRAVEFQEAQAYADDNSLLFMETSAKTAMNVNEIF 175
           +KE++  A P I   L GN+  LA KR V  ++A+ YA  N++   E S     N+ E F
Sbjct: 512 LKEVEEHA-PGIPKVLVGNRLHLAYKRQVAAKQAETYASRNNMSCFEISPLCDFNIRESF 336

Query: 176 MAIAK 180
             +A+
Sbjct: 335 CELAR 321
>01972
          Length = 2359

 Score = 77.4 bits (189), Expect(2) = 4e-19,   Method: Compositional matrix adjust.
 Identities = 39/113 (34%), Positives = 65/113 (57%)
 Frame = +3

Query: 70  VKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNTDTFARAKNWVKELQRQASPNIVI 129
           +KF +WDTAGQE++  L   YY   Q A++++D+T+  T+    NW ++L R    NI I
Sbjct: 447 LKFNVWDTAGQEKFGGLRDGYYIQGQCAVIMFDVTSRVTYKNVPNWHRDLVRVCE-NIPI 623

Query: 130 ALAGNKADLASKRAVEFQEAQAYADDNSLLFMETSAKTAMNVNEIFMAIAKKL 182
            L GNK D+  ++     +A  +    +L + + SAK+  N  + F+ +A+KL
Sbjct: 624 VLCGNKVDIKDRKVK--AKAIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKL 776

 Score = 33.9 bits (76), Expect(2) = 4e-19,   Method: Compositional matrix adjust.
 Identities = 14/27 (51%), Positives = 20/27 (74%)
 Frame = +1

Query: 22  FKLVLLGESAVGKSSLVLRFVKGQFHE 48
           FKLVL+G+  VGK++ V R V G+F +
Sbjct: 304 FKLVLVGDGGVGKTTFVKRHVTGEFEK 384
>05468
          Length = 1558

 Score = 89.7 bits (221), Expect = 8e-19,   Method: Compositional matrix adjust.
 Identities = 52/160 (32%), Positives = 89/160 (55%), Gaps = 8/160 (5%)
 Frame = -3

Query: 22   FKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQTVCLD-DTTVKFEIWDTAGQ 80
            +K++++GE   GK+S++ R+V   F ++  +TIG  F  + +  D DT ++ ++WD AGQ
Sbjct: 1538 YKILVIGELGTGKTSIIKRYVHQFFSQHYRATIGVDFALKVLNWDADTLIRLQLWDIAGQ 1359

Query: 81   ERYHSLAPMYYRGAQAAIVVYDITNTDTFARAKNWVKELQRQ-----ASPNIVIALAGNK 135
            ER+ ++  +YY+ A  A VV+D+T   TF     W  +L  +      SP   + LA NK
Sbjct: 1358 ERFGNMTRVYYKEAVGAFVVFDVTRASTFDAVTKWKNDLDSKVQLADGSPVPCVLLA-NK 1182

Query: 136  ADLASKRAVE--FQEAQAYADDNSLLFMETSAKTAMNVNE 173
             D A +  V    Q  +  ++   + + ETSAK  +N++E
Sbjct: 1181 CDQAKEGLVNNTSQMDEFCSEKGFIGWYETSAKENINIDE 1062
>14119
          Length = 602

 Score = 87.0 bits (214), Expect = 5e-18,   Method: Compositional matrix adjust.
 Identities = 44/78 (56%), Positives = 59/78 (75%), Gaps = 1/78 (1%)
 Frame = +1

Query: 108 TFARAKNWVKELQRQASPNIVIALAGNKADLASK-RAVEFQEAQAYADDNSLLFMETSAK 166
           TF RA  WVKEL++Q + +++I LAGNKADLAS+ RAV   +A+ +A+DN L+F E SAK
Sbjct: 1   TFNRALAWVKELRQQNAGSVLIVLAGNKADLASEHRAVSADDARTFAEDNGLIFAEVSAK 180

Query: 167 TAMNVNEIFMAIAKKLPK 184
           T M V+E+FM IA KL +
Sbjct: 181 TGMAVSEVFMTIAHKLVR 234
>26536
          Length = 829

 Score = 85.9 bits (211), Expect = 1e-17,   Method: Compositional matrix adjust.
 Identities = 49/138 (35%), Positives = 73/138 (52%), Gaps = 3/138 (2%)
 Frame = +2

Query: 51  ESTIGAAFLTQTVCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNTDTFA 110
           E TI    LT    + +  V +   DTAGQE Y S+   Y R     IVVY +T+  +F 
Sbjct: 71  ERTIMLLSLTTMKMMMERRVSWTFLDTAGQEEYSSMREHYTRSGDGFIVVYSVTDVTSFQ 250

Query: 111 RAK---NWVKELQRQASPNIVIALAGNKADLASKRAVEFQEAQAYADDNSLLFMETSAKT 167
            A+    W+   Q + S + V  L GNK DL S R V  +E +  AD   +L+ ETSAKT
Sbjct: 251 EAEAVFRWLTRFQDETSIHAV--LCGNKTDLTSDRKVTPEEGRKMADRLGMLYFETSAKT 424

Query: 168 AMNVNEIFMAIAKKLPKN 185
             NV++++  + + +P++
Sbjct: 425 GDNVSQVYHGLLRSIPRS 478

 Score = 35.8 bits (81), Expect = 0.012,   Method: Compositional matrix adjust.
 Identities = 15/39 (38%), Positives = 24/39 (61%)
 Frame = +2

Query: 20  CQFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAF 58
             +K+V+LG   VGKSSL +RF +  F +  + TI  ++
Sbjct: 482 TDYKIVMLGSGGVGKSSLTIRFTQDTFLDVYDPTIEDSY 598
>11257
          Length = 1102

 Score = 85.9 bits (211), Expect = 1e-17,   Method: Compositional matrix adjust.
 Identities = 52/159 (32%), Positives = 83/159 (52%), Gaps = 5/159 (3%)
 Frame = -2

Query: 61   QTVCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNTDTFARAKNWVKELQ 120
            + V +D  T   +IWDTAGQERY SL   +YRG    ++ + + N  +     +W  E  
Sbjct: 1053 KDVVVDGETFTMQIWDTAGQERYKSLRTPFYRGTDCCLLTFSVDNLKSLQSLSDWYDEFV 874

Query: 121  R----QASPNIVIALAGNKADLASKRAVEFQEAQAYADDN-SLLFMETSAKTAMNVNEIF 175
                 Q S +    + GNKAD+  +R V  ++A  +   + +L + ETSAK ++NV + F
Sbjct: 873  NYADIQDSASFPFVIIGNKADI-EEREVSSEDAYNWCRTHGNLPYFETSAKDSLNVQQAF 697

Query: 176  MAIAKKLPKNEPQNAAGAPGRTRGVDLQESNPASRSQCC 214
            +A+ ++L + + Q     P RT  VDL+      +S CC
Sbjct: 696  LAVVRRLREMDEQ-MDERPTRTDTVDLKRVAKV-KSSCC 586
>13750
          Length = 503

 Score = 84.7 bits (208), Expect = 3e-17,   Method: Compositional matrix adjust.
 Identities = 53/159 (33%), Positives = 77/159 (48%), Gaps = 8/159 (5%)
 Frame = -2

Query: 34  KSSLVLRFVKGQFHEYQESTIGAAFLTQTVC-------LDDTTVKFEIWDTAGQERYHSL 86
           K+ L+ R+ KG F +    TI        +C        D   V++ +WDT G E Y SL
Sbjct: 502 KTCLLRRYQKGFFMDRTMPTIAV------LCSEFNESRTDPLNVRYTLWDTGGAETYRSL 341

Query: 87  APMYYRGAQAAIVVYDITNTDTFARAKN-WVKELQRQASPNIVIALAGNKADLASKRAVE 145
              ++RGAQ A++VYD+T   +F  A   W K L +   P   +   G+K DL   R + 
Sbjct: 340 WVSHFRGAQVALLVYDVTCEWSFLTATTVWRKALMKNI-PEAQVIFVGSKTDLEENRVIS 164

Query: 146 FQEAQAYADDNSLLFMETSAKTAMNVNEIFMAIAKKLPK 184
            +  QA+A      F ETS+ T  NV+ +F  IA  L +
Sbjct: 163 TERGQAFATQCGYTFFETSSVTGKNVDAVFWEIAFILAR 47
>25618
          Length = 475

 Score = 84.0 bits (206), Expect = 4e-17,   Method: Compositional matrix adjust.
 Identities = 46/94 (48%), Positives = 63/94 (67%), Gaps = 1/94 (1%)
 Frame = +3

Query: 117 KELQRQASPNIVIALAGNKADLASK-RAVEFQEAQAYADDNSLLFMETSAKTAMNVNEIF 175
           KEL++Q + +++I LAGNKADLAS+ RAV   +A+ +A+DN L+F E SAKT M V+E+F
Sbjct: 48  KELRQQNAGSVLIVLAGNKADLASEHRAVSADDARTFAEDNGLIFAEVSAKTGMAVSEVF 227

Query: 176 MAIAKKLPKNEPQNAAGAPGRTRGVDLQESNPAS 209
           M IA KL +   +      GR R V L E+  AS
Sbjct: 228 MTIAHKLVRRAEEGQGSXQGRER-VRLSEAEEAS 326
>13901
          Length = 962

 Score = 80.5 bits (197), Expect = 4e-16,   Method: Compositional matrix adjust.
 Identities = 36/95 (37%), Positives = 58/95 (61%), Gaps = 1/95 (1%)
 Frame = -3

Query: 22  FKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQTVCLDD-TTVKFEIWDTAGQ 80
           FK++++G+  VGK+S V R+V   F    + TIG  F  + +   D   +K ++WD AGQ
Sbjct: 285 FKVIIIGDPTVGKTSFVQRYVNDSFRRDYKMTIGVDFALKVIRWSDKCNIKLQLWDIAGQ 106

Query: 81  ERYHSLAPMYYRGAQAAIVVYDITNTDTFARAKNW 115
           ER+ S+  +YY+ A A IV++D+T  +T+  A  W
Sbjct: 105 ERFTSMTRVYYKDAHACIVMFDLTQKNTYQNAIRW 1
>33380
          Length = 282

 Score = 80.5 bits (197), Expect = 5e-16,   Method: Compositional matrix adjust.
 Identities = 35/82 (42%), Positives = 51/82 (62%)
 Frame = +3

Query: 62  TVCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNTDTFARAKNWVKELQR 121
           TV   D  VK +IWDTAGQERY ++   YYRGA   I++YD+TN ++F   ++W  +++ 
Sbjct: 36  TVFRQDKRVKLQIWDTAGQERYRTITTAYYRGAMGFILMYDVTNEESFNAVQDWCTQIKT 215

Query: 122 QASPNIVIALAGNKADLASKRA 143
            +  N  + L GNK DL  +R 
Sbjct: 216 YSWDNAQVVLVGNKCDLEDERV 281
>01398
          Length = 1421

 Score = 80.1 bits (196), Expect = 6e-16,   Method: Compositional matrix adjust.
 Identities = 40/102 (39%), Positives = 58/102 (56%), Gaps = 1/102 (0%)
 Frame = -2

Query: 80   QERYHSLAPMYYRGAQAAIVVYDITNTDTFARAKNWVKELQRQASPNIVIALA-GNKADL 138
            QER+ S+   YYR +   I+VYDIT   TF   K W +E +    P+  I L  G+K+D 
Sbjct: 1420 QERFRSITRSYYRNSVGVIIVYDITKRSTFENLKQWYEEARNHIEPHKAIFLVLGHKSDR 1241

Query: 139  ASKRAVEFQEAQAYADDNSLLFMETSAKTAMNVNEIFMAIAK 180
               R V  +E + +A+ + L F ETSAK+  N+ ++F  IAK
Sbjct: 1240 EDARQVTAREGRRFAEMHGLKFFETSAKSGHNIEDVFAQIAK 1115
>32723
          Length = 384

 Score = 78.6 bits (192), Expect = 2e-15,   Method: Compositional matrix adjust.
 Identities = 42/120 (35%), Positives = 65/120 (54%)
 Frame = +2

Query: 80  QERYHSLAPMYYRGAQAAIVVYDITNTDTFARAKNWVKELQRQASPNIVIALAGNKADLA 139
           QER+ S+   YYR A A I+VYD+ +  ++     W+ E++  A   ++  L GNK D  
Sbjct: 2   QERFRSITQSYYRSANALILVYDVCSQQSYESLPQWIHEIELYAGTKVLAFLVGNKIDQT 181

Query: 140 SKRAVEFQEAQAYADDNSLLFMETSAKTAMNVNEIFMAIAKKLPKNEPQNAAGAPGRTRG 199
            KR +     + +A+   + F+ETSAK A NV ++F  IA +L   + Q   GA   T+G
Sbjct: 182 DKREIPTHIGKEFAERYEMRFLETSAKEADNVEKLFSTIAYQL-TAQAQGTLGAEA*TQG 358
>19006
          Length = 568

 Score = 78.2 bits (191), Expect = 2e-15,   Method: Compositional matrix adjust.
 Identities = 41/117 (35%), Positives = 63/117 (53%), Gaps = 1/117 (0%)
 Frame = -2

Query: 23  KLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQTVCLDDTTVKFEIWDTAGQER 82
           KLV++G+ A GK+ L++ F K QF E    T+   ++   + +D   V+  +WDTAGQE 
Sbjct: 432 KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVAD-IEVDSKQVELALWDTAGQED 256

Query: 83  YHSLAPMYYRGAQAAIVVYDITNTDTFAR-AKNWVKELQRQASPNIVIALAGNKADL 138
           Y  L P+ Y      ++ + I + D+     + W  E+ R   PN+ I L GNK DL
Sbjct: 255 YDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEV-RHFCPNVPIILVGNKKDL 88
>30760
          Length = 596

 Score = 77.8 bits (190), Expect = 3e-15,   Method: Compositional matrix adjust.
 Identities = 51/168 (30%), Positives = 82/168 (48%), Gaps = 6/168 (3%)
 Frame = -1

Query: 23  KLVLLGESAVGKSSL--VLRFVKGQFHEYQESTIGAAFLTQTVCLDDT--TVKFEIWDTA 78
           K ++ G+S VGKSS+  V       F +    T G   L + V + D+   V+  ++D+A
Sbjct: 524 KCIVTGDSGVGKSSICQVFHSDSAHFPKNYSMTTGVEVLVKLVNIPDSRDQVELYLFDSA 345

Query: 79  GQERYHSLAPMYYRGAQAAIVVYDITNTDTFARAKNWVKELQRQASPNIVI--ALAGNKA 136
           G+E +      ++      +VVYD+T+  +F+    W++ + R A PN VI   L  NK 
Sbjct: 344 GKEIFSENVTKFWDQPSVVMVVYDVTDETSFSGCVRWLERV-RAAKPNTVIPGVLVANKT 168

Query: 137 DLASKRAVEFQEAQAYADDNSLLFMETSAKTAMNVNEIFMAIAKKLPK 184
           DL  +R V  +E +  A  + L + E SAK   N +  F  +A    K
Sbjct: 167 DLDERRRVSRKEGKDLAQSHGLEYFECSAKEMQNTDTPFFCLAHAFHK 24
>34359
          Length = 1042

 Score = 74.3 bits (181), Expect = 4e-14,   Method: Compositional matrix adjust.
 Identities = 44/141 (31%), Positives = 71/141 (50%), Gaps = 4/141 (2%)
 Frame = +3

Query: 22  FKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQTVCLDDTTVKFEIWDTAGQE 81
           FKLVL+G      +++V R V G   +Y  +T+G              ++F +WDTAGQE
Sbjct: 54  FKLVLVGGRWEWANNIVKRHVTGS*KKY-VATLGVEVHPLQFNTSRGLLRFNVWDTAGQE 230

Query: 82  RYHSLAPMYYRGAQAAIVVYDITNTDTFARAKNWVKELQRQASPNIVIALAGNKADLASK 141
           ++  L   YY     AI+++D+T+  T+    NW ++L R    NI I L GNK D+  +
Sbjct: 231 KFGGLRDGYYIQGTCAIIMFDVTSRVTYKNVPNWHRDLVRVCE-NIPIVLCGNKVDIKDR 407

Query: 142 ----RAVEFQEAQAYADDNSL 158
               +A+ F   +  +   S+
Sbjct: 408 KVKAKAIVFHRKRTCSTTTSV 470
>12339
          Length = 578

 Score = 73.6 bits (179), Expect = 6e-14,   Method: Compositional matrix adjust.
 Identities = 48/140 (34%), Positives = 67/140 (47%), Gaps = 6/140 (4%)
 Frame = -2

Query: 80  QERYHSLAPMYYRGAQAAIVVYDITNTDTFARAKNWVKELQRQASP----NIVIALAGNK 135
           QER+ SL   +YRGA   I+VYD+T   TF    +W +E   QASP    +    + GNK
Sbjct: 577 QERFQSLGVAFYRGADCCILVYDVTEXKTFDSLDSWQREFLNQASPRDPEHFPFVVIGNK 398

Query: 136 ADLASKRAVEFQEAQAY-ADDNSLLFMETSAKTAMNVNEIFMAIAKK-LPKNEPQNAAGA 193
            DL   R V  +  Q + +    + + ETSAK A+NV + F  +AK  L +         
Sbjct: 397 IDL-DNRVVTAKRGQGWCSTKGGIPYFETSAKEAINVEQAFQTVAKNALAQESEVEIDDF 221

Query: 194 PGRTRGVDLQESNPASRSQC 213
           P   R +   +S P  R  C
Sbjct: 220 PSEIR-LSNDDSRPRERCAC 164
>09204
          Length = 1051

 Score = 71.6 bits (174), Expect = 2e-13,   Method: Compositional matrix adjust.
 Identities = 40/108 (37%), Positives = 61/108 (56%), Gaps = 4/108 (3%)
 Frame = -3

Query: 82   RYHSLAPMYYRGAQAAIVVYDITNTDTFARAKNWVKELQRQASPNIVIALAGNKADLA-- 139
            RY +++ +YYRGA+AAI+ +D+T+  +F R + W+ EL RQ      + + G K DL   
Sbjct: 1049 RYEAMSRIYYRGAKAAILCFDLTDKSSFDRIRFWIGEL-RQHEEECKLYICGTKFDLVHD 873

Query: 140  --SKRAVEFQEAQAYADDNSLLFMETSAKTAMNVNEIFMAIAKKLPKN 185
               +RAV    A+A ADD      ETS+ T  N+ ++F  IA+   K 
Sbjct: 872  DPERRAVPRSVAKALADDCMAEIYETSSMTGDNIEKLFTKIAEDYMKE 729
>35581
          Length = 364

 Score = 70.1 bits (170), Expect = 6e-13,   Method: Compositional matrix adjust.
 Identities = 35/82 (42%), Positives = 50/82 (60%), Gaps = 1/82 (1%)
 Frame = +2

Query: 22  FKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQTVCLDDTTV-KFEIWDTAGQ 80
           FK VLLG++ VGK+ L+ R    +F +   +++  A L  TV L    +   ++WDTAGQ
Sbjct: 47  FKCVLLGDAGVGKTCLLNRLATDKFLDSPLTSLTTASLLTTVTLTSGVMASVDLWDTAGQ 226

Query: 81  ERYHSLAPMYYRGAQAAIVVYD 102
           ERY SL   YYR  +A ++VYD
Sbjct: 227 ERYRSLTSSYYRDTKAVLIVYD 292
>13745
          Length = 1045

 Score = 69.7 bits (169), Expect = 7e-13,   Method: Compositional matrix adjust.
 Identities = 38/105 (36%), Positives = 55/105 (52%), Gaps = 4/105 (3%)
 Frame = +2

Query: 80  QERYHSLAPMYYRGAQAAIVVYDITNTDTFARAKNWVKELQRQASP----NIVIALAGNK 135
           QER+ SL   +YRGA   ++VYD+T  ++F    +W  E   QASP    +    + GNK
Sbjct: 2   QERFQSLGVAFYRGADCCVLVYDVTAPNSFKNLDSWRDEFLIQASPRDPEHFPFVVLGNK 181

Query: 136 ADLASKRAVEFQEAQAYADDNSLLFMETSAKTAMNVNEIFMAIAK 180
            DL +++    +  Q     N + + ETSAK  +NV   F  IAK
Sbjct: 182 VDLDNRQVSTRRAQQWCQSKNDIPYYETSAKEGINVEMAFQTIAK 316
>00858
          Length = 1658

 Score = 63.2 bits (152), Expect = 7e-11,   Method: Compositional matrix adjust.
 Identities = 46/166 (27%), Positives = 89/166 (53%), Gaps = 1/166 (0%)
 Frame = -2

Query: 18   KICQFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQTVCLDDTTVKFEIWDT 77
            ++ ++KLV++G   VGKS+L ++  +  F E  + T   +   Q V +D  T   +I DT
Sbjct: 1600 QMTEYKLVVVGAGGVGKSALTIQLXQNHFVEEYDPTXEDSXRKQVV-IDGETCLLDILDT 1424

Query: 78   AGQERYHSLAPMYYRGAQAAIVVYDITNTDTFARAKNWVKELQR-QASPNIVIALAGNKA 136
            AGQE   ++     R  +  + V+ + N  +F     + ++++R + +  + + L GNK 
Sbjct: 1423 AGQEEXSAMRDQCMRTGEGFLCVFAVXNLKSFEDINQYREQIKRVKDADEVPMVLVGNKV 1244

Query: 137  DLASKRAVEFQEAQAYADDNSLLFMETSAKTAMNVNEIFMAIAKKL 182
            DL   R VE ++ +  A+   + ++ETSAKT   V++ F  + +++
Sbjct: 1243 DLPI-RNVEQRQGKHMAELYHIPYVETSAKTRQGVDDAFYTLVREI 1109
>11728
          Length = 635

 Score = 63.2 bits (152), Expect = 8e-11,   Method: Compositional matrix adjust.
 Identities = 35/118 (29%), Positives = 56/118 (47%), Gaps = 1/118 (0%)
 Frame = -1

Query: 22  FKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQTVCLDDTTVKFEIWDTAGQE 81
            K V++G+ AVGK+ L++ +    F      T+   + +  V +D   +   +WDTAGQE
Sbjct: 488 IKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNY-SANVMVDSKPINLGLWDTAGQE 312

Query: 82  RYHSLAPMYYRGAQAAIVVYDITNTDTFARAK-NWVKELQRQASPNIVIALAGNKADL 138
            Y  L P+ Y      ++ + + +  +F   K  W  E+     PN  I L G K DL
Sbjct: 311 DYDRLRPLSYPQTDVFLICFSLISPASFENVKAKWYPEVSHHC-PNTPIILVGTKLDL 141
>27191
          Length = 443

 Score = 59.3 bits (142), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 24/103 (23%), Positives = 56/103 (54%)
 Frame = +1

Query: 34  KSSLVLRFVKGQFHEYQESTIGAAFLTQTVCLDDTTVKFEIWDTAGQERYHSLAPMYYRG 93
           K+ L+  F + +F++  + T+G  +  +   ++   ++  +WD +G   Y  +    Y G
Sbjct: 1   KTCLIKHFCESKFNQGYQPTVGVDYGFKIQTVNGVDMRVHMWDLSGSNEYLDVRNELYTG 180

Query: 94  AQAAIVVYDITNTDTFARAKNWVKELQRQASPNIVIALAGNKA 136
           + A  +V+D++NT +F    +W++E+ R A+ + +  + GN+ 
Sbjct: 181 SDAIFIVFDVSNTPSFEALDSWLREINRFATGSPLNVIVGNRV 309
>10708
          Length = 2775

 Score = 38.5 bits (88), Expect(2) = 9e-09,   Method: Compositional matrix adjust.
 Identities = 27/76 (35%), Positives = 37/76 (48%), Gaps = 13/76 (17%)
 Frame = -3

Query: 113  KNWVKELQRQASPNIVIALAGNKADLA----SKR--------AVEFQEAQAYADD-NSLL 159
            K W  E+ R   PN+ I L GNK DL     +KR         V   E +A ++  N+  
Sbjct: 2590 KKWTPEV-RHFCPNVPIILVGNKKDLRNDENTKRELMKMKQEPVRLDEGRAMSEKINAYS 2414

Query: 160  FMETSAKTAMNVNEIF 175
            ++E SAKT   V E+F
Sbjct: 2413 YLECSAKTKEGVREVF 2366

 Score = 37.4 bits (85), Expect(2) = 9e-09,   Method: Compositional matrix adjust.
 Identities = 14/40 (35%), Positives = 22/40 (55%)
 Frame = -2

Query: 70   VKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNTDTF 109
            V+  +WDTAGQE Y  L P+ Y      ++ + I + D+ 
Sbjct: 2723 VELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSL 2604
>34597
          Length = 773

 Score = 55.1 bits (131), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 33/110 (30%), Positives = 59/110 (53%), Gaps = 2/110 (1%)
 Frame = -2

Query: 108 TFARAKNWVKELQRQASPNIVIALAGNKADLASKRAVEFQEAQAYADDNSLLFMETSAKT 167
           +F     W++ +   A+ ++   + GNK D+  KR V  +  +A A ++S+ FMETSAK+
Sbjct: 709 SFENIVKWLRNIDEHANEDVEKMILGNKCDMTDKRVVSKERGEAIAREHSIRFMETSAKS 530

Query: 168 AMNVNEIFMAIAKK-LPKNEPQNAAGAPGRTRGVDLQESNPA-SRSQCCS 215
            +N+   F  +A+  L K   + +A  P R   +D   S+ A   ++CC+
Sbjct: 529 NINIERAFCELAEAILDKTAGRESAENPERV-VIDRGNSDKAPGYNKCCA 383
>14775
          Length = 380

 Score = 54.3 bits (129), Expect = 4e-08,   Method: Compositional matrix adjust.
 Identities = 42/158 (26%), Positives = 61/158 (38%), Gaps = 7/158 (4%)
 Frame = -2

Query: 34  KSSLVLRFVKGQFHEYQESTIGAAFLTQTVC-------LDDTTVKFEIWDTAGQERYHSL 86
           K+ L+ R+ KG F +    TI        +C        D   V++ +WDT G E Y SL
Sbjct: 379 KTCLLRRYQKGFFMDRTMPTIAV------LCSEFNESRTDPLNVRYTLWDTGGAETYRSL 218

Query: 87  APMYYRGAQAAIVVYDITNTDTFARAKNWVKELQRQASPNIVIALAGNKADLASKRAVEF 146
              ++RGAQ A++VYD+T                                          
Sbjct: 217 WVSHFRGAQVALLVYDVTC----------------------------------------- 161

Query: 147 QEAQAYADDNSLLFMETSAKTAMNVNEIFMAIAKKLPK 184
           +  QA+A      F ETS+ T  NV+ +F  IA  L +
Sbjct: 160 ERGQAFATQCGYTFFETSSVTGKNVDAVFWEIAFILAR 47
>19656
          Length = 428

 Score = 51.6 bits (122), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 30/103 (29%), Positives = 50/103 (48%), Gaps = 2/103 (1%)
 Frame = +3

Query: 23  KLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQTVCLDDTTVKFEIWDTAGQER 82
           K V++G+ AVGK+ L++ +    F      T+   + +  V +D   V   +WDTAGQE 
Sbjct: 117 KCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNY-SANVMVDGRPVNLGLWDTAGQED 293

Query: 83  YHSLAPMYYRGAQAAIVVYDITNTDTF--ARAKNWVKELQRQA 123
           Y  L P+ Y      ++ + + +  +F   RAK W  E+    
Sbjct: 294 YDRLRPLSYPQTDVFLLCFSVASPASFENIRAK-WYPEVNHHC 419
>00552
          Length = 455

 Score = 46.6 bits (109), Expect = 7e-06,   Method: Compositional matrix adjust.
 Identities = 24/48 (50%), Positives = 30/48 (62%)
 Frame = -1

Query: 22  FKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQTVCLDDTT 69
            K+VLLG+  VGKSSL+ RFV  +F      TIG  FLT+ V +D  T
Sbjct: 443 LKVVLLGDGGVGKSSLMNRFVSNKFDAQSFHTIGVEFLTKDVVVDGET 300

 Score = 46.6 bits (109), Expect = 8e-06,   Method: Compositional matrix adjust.
 Identities = 18/46 (39%), Positives = 25/46 (54%)
 Frame = -3

Query: 74  IWDTAGQERYHSLAPMYYRGAQAAIVVYDITNTDTFARAKNWVKEL 119
           IWDTAGQERY SL   +YRG    ++ + + N  +     +W  E 
Sbjct: 147 IWDTAGQERYKSLRTPFYRGTDCCLLTFSVDNLKSLQSLSDWYDEF 10
>31291
          Length = 446

 Score = 46.2 bits (108), Expect = 9e-06,   Method: Compositional matrix adjust.
 Identities = 22/68 (32%), Positives = 34/68 (50%), Gaps = 1/68 (1%)
 Frame = -1

Query: 72  FEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNTDTFARAK-NWVKELQRQASPNIVIA 130
            ++WDTAGQE Y  L P+ Y      ++ + + +  +    K  W  E+ R   P++ I 
Sbjct: 446 LQLWDTAGQEDYDRLRPLAYPNTDVFMLXFSLMSEASMKNVKVKWYPEI-RHHDPHVPIV 270

Query: 131 LAGNKADL 138
           L G K DL
Sbjct: 269 LVGTKLDL 246
>10862
          Length = 2896

 Score = 42.0 bits (97), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 26/83 (31%), Positives = 39/83 (46%), Gaps = 5/83 (6%)
 Frame = -3

Query: 71   KFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNTDTFARAKNWVKELQR----QASPN 126
            +F +WD  GQ++   L   YY G Q  I V D  + D    A+   +EL R    +   +
Sbjct: 2483 QFNVWDVGGQDKIRPLWRHYYTGTQGLIFVVDCADRDRIDEAR---QELHRIINDREMRD 2313

Query: 127  IVIALAGNKADLA-SKRAVEFQE 148
             +I +  NK DL  + +  E QE
Sbjct: 2312 AIILIFANKQDLPDAMKPHEIQE 2244
>08153
          Length = 1703

 Score = 42.0 bits (97), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 32/122 (26%), Positives = 59/122 (48%), Gaps = 4/122 (3%)
 Frame = +1

Query: 21  QFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQTVCLDDTTVKFEIWDTAGQ 80
           + +++++G  A GK++++ +   G+       TIG  F  +TV  +   + F +WD  GQ
Sbjct: 82  EVRILMVGLDAAGKTTILYKLKLGEIVT-TIPTIG--FNVETV--EYKNISFTVWDVGGQ 246

Query: 81  ERYHSLAPMYYRGAQAAIVVYDITNTDTFARAKNWVKELQRQASP----NIVIALAGNKA 136
           ++   L   Y++  Q  I V D  + +    AK   +EL R  +     + +I +  NK 
Sbjct: 247 DKIRPLWRHYFQNTQGLIFVVDSNDRERINEAK---EELARMLNEDDLRDAIILVFANKQ 417

Query: 137 DL 138
           DL
Sbjct: 418 DL 423
>09827
          Length = 1201

 Score = 39.7 bits (91), Expect = 9e-04,   Method: Compositional matrix adjust.
 Identities = 31/120 (25%), Positives = 58/120 (48%), Gaps = 4/120 (3%)
 Frame = -3

Query: 23   KLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQTVCLDDTTVKFEIWDTAGQER 82
            +++++G  A GK++++ +   G+       TIG  F  +TV  +   + F +WD  GQ++
Sbjct: 1109 RILMVGLDAAGKTTILYKLKLGEIVT-TIPTIG--FNVETV--EYKNISFTVWDVGGQDK 945

Query: 83   YHSLAPMYYRGAQAAIVVYDITNTDTFARAKNWVKELQRQASP----NIVIALAGNKADL 138
               L   Y++  Q  I V D  + +    A+   +EL R  +     + V+ +  NK DL
Sbjct: 944  IRPLWRHYFQNTQGLIFVVDSNDKERVQEAR---EELTRMLNEDELRDAVLLVFANKQDL 774
>18509
          Length = 625

 Score = 35.4 bits (80), Expect = 0.017,   Method: Compositional matrix adjust.
 Identities = 19/58 (32%), Positives = 34/58 (58%)
 Frame = -3

Query: 127 IVIALAGNKADLASKRAVEFQEAQAYADDNSLLFMETSAKTAMNVNEIFMAIAKKLPK 184
           + + L GNK DL   R VE ++ +  A+   + ++ETSAKT   V++ F  + +++ K
Sbjct: 527 VPMVLVGNKVDLPI-RNVEQRQGKHMAELYHIPYVETSAKTRQGVDDAFYTLVREIRK 357
>06994
          Length = 429

 Score = 34.3 bits (77), Expect = 0.040,   Method: Compositional matrix adjust.
 Identities = 15/28 (53%), Positives = 22/28 (78%)
 Frame = +3

Query: 21 QFKLVLLGESAVGKSSLVLRFVKGQFHE 48
          ++KLV+LG   VGKS+L ++FV+G F E
Sbjct: 54 EYKLVVLGSGGVGKSALTVQFVQGIFVE 137
>33605
          Length = 888

 Score = 32.3 bits (72), Expect = 0.15,   Method: Compositional matrix adjust.
 Identities = 20/82 (24%), Positives = 37/82 (45%)
 Frame = +1

Query: 21  QFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQTVCLDDTTVKFEIWDTAGQ 80
           + +L++LG    GK++++ +F  G+  +    T+G    T    L+    K  +WD  GQ
Sbjct: 496 EVRLLMLGLDNAGKTTILKKF-NGEDIDTISPTLGFNIKT----LEHRGFKLNVWDVGGQ 660

Query: 81  ERYHSLAPMYYRGAQAAIVVYD 102
           +   S    Y+      + V D
Sbjct: 661 QSLRSYWRNYFESTDGLVWVVD 726
>34156
          Length = 348

 Score = 31.2 bits (69), Expect = 0.37,   Method: Compositional matrix adjust.
 Identities = 17/53 (32%), Positives = 30/53 (56%)
 Frame = -1

Query: 21  QFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQTVCLDDTTVKFE 73
           +F L+++GES +GKS+LV        +  +     +  + QTV +D +TV+ E
Sbjct: 198 EFTLMVVGESGLGKSTLVNSLFLTDLYPERHIPSASEKIQQTVKIDASTVEIE 40
>30516
          Length = 606

 Score = 28.1 bits (61), Expect = 2.8,   Method: Compositional matrix adjust.
 Identities = 17/59 (28%), Positives = 25/59 (42%)
 Frame = +2

Query: 21  QFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQTVCLDDTTVKFEIWDTAG 79
           + ++VLLG++  GKSSL    +          T      TQ  C D      ++ DT G
Sbjct: 170 RLRVVLLGKTGSGKSSLGNTLLGKDTFRVMPGTSSGTKDTQRECADRFGTMIQVTDTPG 346
>25991
          Length = 847

 Score = 26.6 bits (57), Expect = 9.2,   Method: Compositional matrix adjust.
 Identities = 11/35 (31%), Positives = 21/35 (60%)
 Frame = -1

Query: 19  ICQFKLVLLGESAVGKSSLVLRFVKGQFHEYQEST 53
           + + K  L+GE+  G  ++   FV+G+F +  +ST
Sbjct: 358 LIRLKSSLVGETDPGDGTVAEGFVRGRFKDESKST 254
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|13385854|ref|NP_080628.1| peptidylprolyl isomerase D
[Mus musculus]
         (370 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

03857                                                                 293   8e-80
07030                                                                 197   6e-51
05336                                                                 197   8e-51
00176                                                                 194   7e-50
23478                                                                 193   1e-49
03374                                                                 174   8e-44
07382                                                                 159   2e-39
15913                                                                 154   5e-38
12711                                                                 125   3e-29
11676                                                                 120   1e-27
06379                                                                  82   5e-27
12506                                                                 111   4e-25
05986                                                                 111   6e-25
14547                                                                 100   8e-22
00888                                                                  81   6e-16
02140                                                                  75   4e-14
08983                                                                  72   5e-13
13560                                                                  67   9e-12
30337                                                                  54   9e-08
15093                                                                  52   6e-07
23338                                                                  50   1e-06
32109                                                                  47   1e-05
13072                                                                  36   8e-05
21265                                                                  32   0.44 
19619                                                                  31   0.72 
>03857
          Length = 1696

 Score =  293 bits (750), Expect = 8e-80,   Method: Compositional matrix adjust.
 Identities = 151/301 (50%), Positives = 194/301 (64%), Gaps = 6/301 (1%)
 Frame = +1

Query: 76  IIKKFMIQGGDFSNQNGTGGESIYGEKFEDENFHYKHDREGLLSMANAGPNTNGSQFFIT 135
           +IK FMIQGGDF+N NGTGGESIYG+KF+DE+F  KHD   LLSMANAGPNTNGSQFFIT
Sbjct: 13  VIKDFMIQGGDFTNHNGTGGESIYGDKFDDESFDRKHDCPMLLSMANAGPNTNGSQFFIT 192

Query: 136 TVPTPHLDGKHVVFGQVIKGLGVARTLENVEVNGEKPAKLCVIAECGELKEGDDWGIFPK 195
           TVPTPHLDGKHVVFG+VI G  V R LENV+ +GE P K C IA+CGEL    D   F K
Sbjct: 193 TVPTPHLDGKHVVFGEVIAGHNVVRELENVDKDGETPTKTCSIADCGELAADCDVTTFNK 372

Query: 196 DGSGDSHPDFPEXXXXXXXXXXXXXXXSE---DLKNIGNTFFKSQNWEMAIKKYAKVLRY 252
           D SGD H D+P                 +   D+K  GNT FK+  +  A +KY K LRY
Sbjct: 373 DDSGDVHADYPGDSSIDFTADSCGEEVRKVVLDVKQAGNTLFKAGKFGPANRKYKKALRY 552

Query: 253 ---VDSSKAVIEKADRSRLQPIALSCVLNIGACKLKMSNWQGAIDSCLEALEMDPSNTKA 309
              +D  + + E   ++  + + +   LN  AC LK++ +  A++ C E LE DP N+KA
Sbjct: 553 LQKLDEEQKMSEDQQKAMEKELHIPVSLNAAACCLKLNKYNEALEYCQEVLEADPDNSKA 732

Query: 310 LYRKAQGWQGLKEYDQALADLKKAQEIAPGDKAIQAELLKVKQMIKAQKDKEKAVYAKMF 369
            YR+ Q   G K+Y+ ALA  +KA    P DK I+ E+ KVK+ ++ +K +EK +Y++MF
Sbjct: 733 QYRQGQAHAGNKDYETALASFQKALAANPDDKGIKLEIQKVKRTVEEEKKREKQMYSRMF 912

Query: 370 A 370
           A
Sbjct: 913 A 915
>07030
          Length = 2391

 Score =  197 bits (501), Expect = 6e-51,   Method: Compositional matrix adjust.
 Identities = 97/172 (56%), Positives = 124/172 (72%), Gaps = 1/172 (0%)
 Frame = +2

Query: 15  NPRVFFDVDIGGERVGRIVLELFADIVPKTAENFRALCXXXXXXXXXXXXPLHFKGCPFH 74
             +VFFD++IGGE+ GRIV+ LF DIVPKTA+NF++L              L +KG  FH
Sbjct: 158 TDKVFFDIEIGGEKAGRIVIGLFGDIVPKTAKNFKSLAVGFKDKDDN---TLTYKGSKFH 328

Query: 75  RIIKKFMIQGGDFSNQNGTGGESIYGEKFEDENFHYKHDREGLLSMANAGPNTNGSQFFI 134
           R+IK FMIQGGDF+  +GTGG+SIYGEKF DENF   H   G LSMANAG +TNGSQFF+
Sbjct: 329 RVIKDFMIQGGDFTRGDGTGGKSIYGEKFADENFKLNHYGAGWLSMANAGKDTNGSQFFL 508

Query: 135 TTVPTPHLDGKHVVFGQVIKGLGVARTLENVEVNG-EKPAKLCVIAECGELK 185
           TT  T  LDG+HVVFG+V++G+ V R +E+ + +G +KP K  VIA+ GE+K
Sbjct: 509 TTKTTSWLDGRHVVFGKVLEGMSVVRKIESTKTDGRDKPHKDVVIADSGEIK 664
>05336
          Length = 1406

 Score =  197 bits (500), Expect = 8e-51,   Method: Compositional matrix adjust.
 Identities = 99/172 (57%), Positives = 118/172 (68%)
 Frame = +3

Query: 13  SKNPRVFFDVDIGGERVGRIVLELFADIVPKTAENFRALCXXXXXXXXXXXXPLHFKGCP 72
           SK PRV+FD+   G+ +GRI  ELFAD+VPKTAENFR+LC               FK   
Sbjct: 99  SKRPRVYFDMTADGDEIGRIEFELFADVVPKTAENFRSLCTGEKG--------FGFKNSI 254

Query: 73  FHRIIKKFMIQGGDFSNQNGTGGESIYGEKFEDENFHYKHDREGLLSMANAGPNTNGSQF 132
           FHR+I +FM QGGD +  NGTGG+SIYG KFEDENF  KH + GLLSMANAGP+TNGSQF
Sbjct: 255 FHRVIPEFMCQGGDITRGNGTGGKSIYGNKFEDENFTMKHTKPGLLSMANAGPDTNGSQF 434

Query: 133 FITTVPTPHLDGKHVVFGQVIKGLGVARTLENVEVNGEKPAKLCVIAECGEL 184
           FITTV T  LDG HVVFG+V KG+ +   +E +   G +  K   IA+CGEL
Sbjct: 435 FITTVVTSWLDGCHVVFGEVSKGMDIVTEIEKLGSRGGQTKKKIAIADCGEL 590
>00176
          Length = 1408

 Score =  194 bits (492), Expect = 7e-50,   Method: Compositional matrix adjust.
 Identities = 97/168 (57%), Positives = 115/168 (68%)
 Frame = -1

Query: 17  RVFFDVDIGGERVGRIVLELFADIVPKTAENFRALCXXXXXXXXXXXXPLHFKGCPFHRI 76
           RV+FD+ IGG   GRIV+EL  D+VPKTAENFRALC               FKG  FHR+
Sbjct: 895 RVYFDMTIGGXDAGRIVMELRTDVVPKTAENFRALCTMEKG--------FGFKGSSFHRV 740

Query: 77  IKKFMIQGGDFSNQNGTGGESIYGEKFEDENFHYKHDREGLLSMANAGPNTNGSQFFITT 136
           I  FM QGGDF+N NGTGG+SIYG KF DENF+ KH   G+LSMANAGP TNGSQFF+ T
Sbjct: 739 IPGFMCQGGDFTNHNGTGGKSIYGAKFADENFNLKHTGPGILSMANAGPGTNGSQFFLCT 560

Query: 137 VPTPHLDGKHVVFGQVIKGLGVARTLENVEVNGEKPAKLCVIAECGEL 184
             T  LDGKHVVFG+V +G+ V + +E V     K +K  VI +CG+L
Sbjct: 559 AETSWLDGKHVVFGKVAEGMEVVKAIEKVGSQSGKTSKPVVIKDCGQL 416
>23478
          Length = 909

 Score =  193 bits (490), Expect = 1e-49,   Method: Compositional matrix adjust.
 Identities = 94/170 (55%), Positives = 114/170 (67%), Gaps = 1/170 (0%)
 Frame = +1

Query: 16  PRVFFDVDIGGERVGRIVLELFADIVPKTAENFRALCXXXXXXXXXXXXPLHFKGCPFHR 75
           PR FFDV IG +  GRIV EL++D  PKT ENFRALC             LH+KG PFHR
Sbjct: 106 PRCFFDVSIGDQPGGRIVFELYSDECPKTCENFRALCTGEKGTSEKTGAVLHYKGAPFHR 285

Query: 76  IIKKFMIQGGDFSNQNGTGGESIYGEKFEDENFHYKHDREGLLSMANAGPNTNGSQFFIT 135
           ++K FM+Q GDF+  +GTGGESIYG  F DENF +KH++E LLSMAN G +TNGSQFFIT
Sbjct: 286 VVKDFMVQCGDFTKGDGTGGESIYGGHFADENFKFKHEKECLLSMANRGKDTNGSQFFIT 465

Query: 136 TVPTPHLDGKHVVFGQVIKGLGVARTLENVEVNGE-KPAKLCVIAECGEL 184
           T P PHLD  HVVFG V+ G  V + +E +  +   +P     +A CGEL
Sbjct: 466 TNPAPHLDNVHVVFGHVLSGQEVVKKIEQLPTDARSRPEVEVKVANCGEL 615
>03374
          Length = 852

 Score =  174 bits (440), Expect = 8e-44,   Method: Compositional matrix adjust.
 Identities = 93/191 (48%), Positives = 117/191 (61%), Gaps = 5/191 (2%)
 Frame = +1

Query: 13  SKNPRV----FFDVDIGGERVGRIVLELFADIVPKTAENFRALCXXXXXXXXXXXXPLHF 68
           SK P+V    FFD+ IGGE  GR+ + LF   V KT  NF+ L                +
Sbjct: 22  SKGPKVTDKVFFDITIGGEPAGRVEIGLFGKTVEKTVRNFKELAEKPQGEG--------Y 177

Query: 69  KGCPFHRIIKKFMIQGGDFSNQNGTGGESIYGEKFEDENFHYKHDREGLLSMANAGPNTN 128
           KG  FHRIIK FMIQGGDF+  +GTGG SIYGE+FEDENF  KH   G LSMANAG +TN
Sbjct: 178 KGSKFHRIIKDFMIQGGDFTKGDGTGGRSIYGERFEDENFKLKHYGAGWLSMANAGKDTN 357

Query: 129 GSQFFITTVPTPHLDGKHVVFGQVIKGLGVARTLENVEVNG-EKPAKLCVIAECGELKEG 187
           GSQFFITT  T  LDG+HVVFG+++ G+ V R +E    +  ++P K  VIA CG +   
Sbjct: 358 GSQFFITTKQTSWLDGRHVVFGKILSGMDVVRKIEASATDARDRPVKDVVIANCGVIAVA 537

Query: 188 DDWGIFPKDGS 198
           + + +   D +
Sbjct: 538 EPFAVSKTDAT 570
>07382
          Length = 1486

 Score =  159 bits (402), Expect = 2e-39,   Method: Compositional matrix adjust.
 Identities = 84/170 (49%), Positives = 106/170 (62%), Gaps = 1/170 (0%)
 Frame = +2

Query: 17  RVFFDVDIGGERVGRIVLELFADIVPKTAENFRALCXXXXXXXXXXXXPLHFKGCPFHRI 76
           +V FD+ I GE  G I + LF D+VPKT  NF AL               ++KG  FHR+
Sbjct: 137 KVVFDISIAGEPAGSIEIGLFGDVVPKTVNNFVAL------XSGQNAFGYNYKGSKFHRV 298

Query: 77  IKKFMIQGGDFSNQNGTGGESIYGEKFEDENFHYKHDREGLLSMANAGPNTNGSQFFITT 136
           I  FMIQGGDF + NG+G +SIYG+ F+DE+F  KH   G +SMAN GPNTNG QFFIT 
Sbjct: 299 ISDFMIQGGDFVHNNGSGSKSIYGDLFDDEDFSVKHYGSGWISMANRGPNTNGCQFFITL 478

Query: 137 VPTPHLDGKHVVFGQVIKGLGVARTLENVEVNG-EKPAKLCVIAECGELK 185
              P LDG HVVFG+VI G+ V R +E+++ N  + P    VI +  E K
Sbjct: 479 RDCPWLDGSHVVFGKVIDGMKVVRKIEDIDTNSVDAPLVDIVITDSREEK 628
>15913
          Length = 1796

 Score =  154 bits (389), Expect = 5e-38,   Method: Compositional matrix adjust.
 Identities = 73/123 (59%), Positives = 86/123 (69%)
 Frame = -1

Query: 16   PRVFFDVDIGGERVGRIVLELFADIVPKTAENFRALCXXXXXXXXXXXXPLHFKGCPFHR 75
            PR FFDV IG +  GRIV EL++D  PKT ENFRALC             LH+KG PFHR
Sbjct: 1742 PRCFFDVSIGDQPGGRIVFELYSDECPKTCENFRALCTGEKGTSEKTGAVLHYKGAPFHR 1563

Query: 76   IIKKFMIQGGDFSNQNGTGGESIYGEKFEDENFHYKHDREGLLSMANAGPNTNGSQFFIT 135
            ++K FM+Q GDF+  +GTGGESIYG  F DENF +KH++E LLSMAN G +TNGSQFFI 
Sbjct: 1562 VVKDFMVQCGDFTKGDGTGGESIYGGHFADENFKFKHEKECLLSMANRGKDTNGSQFFIA 1383

Query: 136  TVP 138
              P
Sbjct: 1382 DRP 1374

 Score = 39.3 bits (90), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 19/47 (40%), Positives = 27/47 (57%), Gaps = 1/47 (2%)
 Frame = -1

Query: 139 TPHLDGKHVVFGQVIKGLGVARTLENVEVNGE-KPAKLCVIAECGEL 184
           +PHLD  HVVFG V+ G  V + +E +  +   +P     +A CGEL
Sbjct: 425 SPHLDNVHVVFGHVLSGQEVVKKIEQLPTDARSRPEVEVKVANCGEL 285
>12711
          Length = 1926

 Score =  125 bits (313), Expect = 3e-29,   Method: Compositional matrix adjust.
 Identities = 71/146 (48%), Positives = 86/146 (58%), Gaps = 2/146 (1%)
 Frame = -2

Query: 29  VGRIVLELFADIVPKTAENFRALCXXXXXXXXXXXXPLHFKGCPFHRIIKKFMIQGGDFS 88
           +G  VLEL+    P T  NF  LC              ++ G  FHRIIK FMIQGGD  
Sbjct: 413 MGTFVLELYWKHAPNTCRNFAELCRRG-----------YYNGIKFHRIIKDFMIQGGD-P 270

Query: 89  NQNGTGGESIYGEKFEDENFH-YKHDREGLLSMANAGPNTNGSQFFITTVPTPHLDGKHV 147
              G GG SIYG+ F DE     KH   G+LSMAN+GPNTNGSQFFIT  PT  LDGKH 
Sbjct: 269 TGTGRGGSSIYGKNFNDEIADDLKHTGAGILSMANSGPNTNGSQFFITLAPTQWLDGKHS 90

Query: 148 VFGQVIKGLGVARTLENVEVNG-EKP 172
           +FG++  G+ V + +  VE +G +KP
Sbjct: 89  IFGRISSGMTVIKRIGMVETDGNDKP 12
>11676
          Length = 499

 Score =  120 bits (301), Expect = 1e-27,   Method: Compositional matrix adjust.
 Identities = 60/105 (57%), Positives = 71/105 (67%), Gaps = 1/105 (0%)
 Frame = -3

Query: 9   KPSNSK-NPRVFFDVDIGGERVGRIVLELFADIVPKTAENFRALCXXXXXXXXXXXXPLH 67
           KP   K   +V+FD++IGGE+ GRIV+ LF   VPKTAENF+ LC             L 
Sbjct: 320 KPKGPKVTDKVYFDIEIGGEKAGRIVIGLFGKTVPKTAENFKQLCIGDQKSEDGK--ELT 147

Query: 68  FKGCPFHRIIKKFMIQGGDFSNQNGTGGESIYGEKFEDENFHYKH 112
           +KG  FHR+IK FMIQGGDF+N +GTGG SIYGEKF DENF  KH
Sbjct: 146 YKGSQFHRVIKDFMIQGGDFTNGDGTGGRSIYGEKFADENFKLKH 12
>06379
          Length = 1672

 Score = 82.4 bits (202), Expect(2) = 5e-27,   Method: Compositional matrix adjust.
 Identities = 40/67 (59%), Positives = 47/67 (70%)
 Frame = -2

Query: 66   LHFKGCPFHRIIKKFMIQGGDFSNQNGTGGESIYGEKFEDENFHYKHDREGLLSMANAGP 125
            LH K   F  ++K    +GGDF+N +GTGG SIYGEKF DENF  KH   G LSMAN+G 
Sbjct: 1062 LHTKAANFTALLKTL*FKGGDFTNGDGTGGRSIYGEKFADENFKLKHYGAGWLSMANSGK 883

Query: 126  NTNGSQF 132
            +TNGSQF
Sbjct: 882  DTNGSQF 862

 Score = 56.6 bits (135), Expect(2) = 5e-27,   Method: Compositional matrix adjust.
 Identities = 26/45 (57%), Positives = 33/45 (73%), Gaps = 1/45 (2%)
 Frame = -3

Query: 9    KPSNSK-NPRVFFDVDIGGERVGRIVLELFADIVPKTAENFRALC 52
            KP   K   +V+FD++IGGE+ GRIV+ LF   VPKTAENF+ LC
Sbjct: 1250 KPKGPKVTDKVYFDIEIGGEKAGRIVIGLFGKTVPKTAENFKQLC 1116

 Score = 70.5 bits (171), Expect = 1e-12,   Method: Compositional matrix adjust.
 Identities = 47/125 (37%), Positives = 67/125 (53%), Gaps = 5/125 (4%)
 Frame = -1

Query: 66   LHFKGCPFHRIIKKFMIQGGDFSNQNGTGGESIYGEKFEDENFHYKHDREGLLS-MANAG 124
            L +KG  FHR+IK FMIQGG F           + E    +    +   E L   +A  G
Sbjct: 1063 LTYKGSQFHRVIKDFMIQGGRFHQW*W----HWWAEYIRRKVC**ELQAEALWGWLAIHG 896

Query: 125  PNTNGSQFF---ITTVPTPHLDGKHVVFGQVIKGLGVARTLENVEVNG-EKPAKLCVIAE 180
                  Q+    ITT  T  LDG+HVVFG+V++G+ V R +EN++ +  +KP K CVIA+
Sbjct: 895  QLWQRHQWLSVLITTKKTTWLDGRHVVFGKVLEGMDVVRRIENMKTSARDKPEKDCVIAD 716

Query: 181  CGELK 185
             G ++
Sbjct: 715  SGAIE 701
>12506
          Length = 1056

 Score =  111 bits (278), Expect = 4e-25,   Method: Compositional matrix adjust.
 Identities = 54/98 (55%), Positives = 65/98 (66%)
 Frame = -1

Query: 9   KPSNSKNPRVFFDVDIGGERVGRIVLELFADIVPKTAENFRALCXXXXXXXXXXXXPLHF 68
           K      P+V+ D+ IG   VGRI+++L AD+VPKTAENFR LC               F
Sbjct: 657 KAXTXXQPQVYMDIKIGNRAVGRIIMQLRADVVPKTAENFRCLCTHEKGYG--------F 502

Query: 69  KGCPFHRIIKKFMIQGGDFSNQNGTGGESIYGEKFEDE 106
           KG  FHRII +FM QGGDF+N NGTGG+SIYG+KFEDE
Sbjct: 501 KGSSFHRIIPQFMCQGGDFTNHNGTGGKSIYGKKFEDE 388

 Score = 95.1 bits (235), Expect = 4e-20,   Method: Compositional matrix adjust.
 Identities = 49/112 (43%), Positives = 60/112 (53%)
 Frame = -2

Query: 73  FHRIIKKFMIQGGDFSNQNGTGGESIYGEKFEDENFHYKHDREGLLSMANAGPNTNGSQF 132
           FH +  + +I            G          +NF  +H   G LSMAN+GPNTNGSQF
Sbjct: 476 FHNLCVRGVIS----PTTTALAGNPSTARSLRTKNFQLRHTAAGDLSMANSGPNTNGSQF 309

Query: 133 FITTVPTPHLDGKHVVFGQVIKGLGVARTLENVEVNGEKPAKLCVIAECGEL 184
           F+TT  T  LDGKHVVFG+VI+GL +   +E     G KP     IA CGEL
Sbjct: 308 FLTTXKTDWLDGKHVVFGRVIEGLDIVNKMEKCGTKGGKPTDKVTIANCGEL 153
>05986
          Length = 1295

 Score =  111 bits (277), Expect = 6e-25,   Method: Compositional matrix adjust.
 Identities = 65/150 (43%), Positives = 89/150 (59%), Gaps = 5/150 (3%)
 Frame = -3

Query: 29   VGRIVLELFADIVPKTAENFRALCXXXXXXXXXXXXPLHFKGCPFHRIIKKFMIQGGDFS 88
            VG I +EL++   PK+  NF  LC              ++ G  FHR++K+F++QGGD +
Sbjct: 1224 VGDIDVELWSKEAPKSCRNFIQLCLEG-----------YYDGTAFHRVVKEFIVQGGDPT 1078

Query: 89   NQNGTGGESIYGEKFEDENFH--YKHDREGLLSMANAGPNTNGSQFFITTVPTPHLDGKH 146
            +  G GGES+YG  F+DE FH   +  R GL++MANAGP+ NGSQFF T   TP L  KH
Sbjct: 1077 D-TGHGGESVYGAPFKDE-FHSRLRFVRRGLVAMANAGPHDNGSQFFFTMAATPELQNKH 904

Query: 147  VVFGQVI-KGLGVARTLENVEVN--GEKPA 173
             +FG+V+   L     L+ VEVN   E+P 
Sbjct: 903  TIFGKVVGDTLYNMLKLQEVEVNEATERPT 814
>14547
          Length = 491

 Score =  100 bits (250), Expect = 8e-22,   Method: Compositional matrix adjust.
 Identities = 52/108 (48%), Positives = 64/108 (59%), Gaps = 1/108 (0%)
 Frame = -1

Query: 12  NSKN-PRVFFDVDIGGERVGRIVLELFADIVPKTAENFRALCXXXXXXXXXXXXPLHFKG 70
           NSKN   V+ D+ IG E  GR+V+EL++D  PKT ENFRALC             L +  
Sbjct: 326 NSKNHDYVYMDISIGEEAAGRLVIELYSDKAPKTCENFRALCTGEKGTSEETDLRLXYLN 147

Query: 71  CPFHRIIKKFMIQGGDFSNQNGTGGESIYGEKFEDENFHYKHDREGLL 118
             FHRI++   IQGGD  +  G GGESI+G  FEDENF   HDR G +
Sbjct: 146 SLFHRIVRNGWIQGGDIYHGRGNGGESIFGTVFEDENFAIPHDRRGCV 3
>00888
          Length = 970

 Score = 81.3 bits (199), Expect = 6e-16,   Method: Compositional matrix adjust.
 Identities = 44/147 (29%), Positives = 80/147 (54%)
 Frame = -3

Query: 223 SEDLKNIGNTFFKSQNWEMAIKKYAKVLRYVDSSKAVIEKADRSRLQPIALSCVLNIGAC 282
           S+ +K  G   FK   ++ A+  Y K++ +++     +  ++ S    + ++  LNI  C
Sbjct: 740 SKIIKEKGTAAFKKGKYQRALTNYEKIVSFLEHESTGLSDSELSDKHQLMVAAFLNIAMC 561

Query: 283 KLKMSNWQGAIDSCLEALEMDPSNTKALYRKAQGWQGLKEYDQALADLKKAQEIAPGDKA 342
           +LK+ +++ A ++C + L M  +N KAL+R+ Q      +Y +A +D  K  E+ PG+KA
Sbjct: 560 QLKLLDYRQAEETCNKVLAMSTNNVKALFRRGQARLECADYTEAASDFSKVLELEPGNKA 381

Query: 343 IQAELLKVKQMIKAQKDKEKAVYAKMF 369
            + + +   Q  KA   KEKA+Y  MF
Sbjct: 380 AKNQHIVCLQKQKADYAKEKALYTNMF 300
>02140
          Length = 1796

 Score = 75.1 bits (183), Expect = 4e-14,   Method: Compositional matrix adjust.
 Identities = 46/143 (32%), Positives = 73/143 (51%), Gaps = 9/143 (6%)
 Frame = +3

Query: 29  VGRIVLELFADIVPKTAENFRALCXXXXXXXXXXXXPLHFKGCPFHRIIKKFMIQGGDFS 88
           +G++ ++L+ +  P+ +ENF  LC              ++    FH + +  + Q GD  
Sbjct: 108 IGQLTVDLYTEERPRCSENFLKLCKVK-----------YYNFSLFHSVQENLVAQTGD-P 251

Query: 89  NQNGTGGESIYGEKFEDENFHY--------KHDREGLLSMANAGPNTNGSQFFITTVPT- 139
              G GG S+YG  + ++  ++        KH + GLLSM N G   +GSQFFIT   + 
Sbjct: 252 TATGRGGMSVYGMVYGEQARYFDMEVSPRIKHKKRGLLSMVNNGAGKHGSQFFITLGESL 431

Query: 140 PHLDGKHVVFGQVIKGLGVARTL 162
            +LDG+H VFG+V +G  V   L
Sbjct: 432 DYLDGEHTVFGEVAEGFEVLDKL 500
>08983
          Length = 430

 Score = 71.6 bits (174), Expect = 5e-13,   Method: Compositional matrix adjust.
 Identities = 45/84 (53%), Positives = 52/84 (61%), Gaps = 1/84 (1%)
 Frame = +3

Query: 72  PFHRIIKKFMIQGGDFSNQNGTGGESIYGEKFEDE-NFHYKHDREGLLSMANAGPNTNGS 130
           PF R   K+      FS   G GG SIYG+ F DE     KH   G+LSMAN+GPNTNGS
Sbjct: 63  PFGRSCGKYRYP---FSGSTGRGGSSIYGKNFNDEIADDLKHTGAGILSMANSGPNTNGS 233

Query: 131 QFFITTVPTPHLDGKHVVFGQVIK 154
           QFFIT  PT  LDGKH +FG  ++
Sbjct: 234 QFFITLAPTQWLDGKHSIFGASVQ 305
>13560
          Length = 978

 Score = 67.4 bits (163), Expect = 9e-12,   Method: Compositional matrix adjust.
 Identities = 43/141 (30%), Positives = 67/141 (47%)
 Frame = +1

Query: 230 GNTFFKSQNWEMAIKKYAKVLRYVDSSKAVIEKADRSRLQPIALSCVLNIGACKLKMSNW 289
           GN F    ++  AI+    VL Y  S     E A  S LQ +   C LN+ AC++K  + 
Sbjct: 232 GNIFAAFSHFRTAIRLLLSVLPYSFSDD---EVASTSHLQLLC-QCYLNLAACQIKSGHH 399

Query: 290 QGAIDSCLEALEMDPSNTKALYRKAQGWQGLKEYDQALADLKKAQEIAPGDKAIQAELLK 349
           +  I +C  AL +DP+N KALYR+A     L     A  DL+   +  P ++A+   +  
Sbjct: 400 KHVITNCTHALNLDPANVKALYRRASANVNLGNLLHAHEDLETGLQKEPNNRALLDLMQN 579

Query: 350 VKQMIKAQKDKEKAVYAKMFA 370
           V   +   + +     +KMF+
Sbjct: 580 VNARLAPSQSQMAQGLSKMFS 642
>30337
          Length = 493

 Score = 53.9 bits (128), Expect = 9e-08,   Method: Compositional matrix adjust.
 Identities = 36/117 (30%), Positives = 54/117 (46%)
 Frame = -1

Query: 225 DLKNIGNTFFKSQNWEMAIKKYAKVLRYVDSSKAVIEKADRSRLQPIALSCVLNIGACKL 284
           DLKN GN  F ++ +E AI  Y         +KA+++        P   +   N   C +
Sbjct: 325 DLKNQGNKLFAARKYEDAIHCY---------TKAIMK-------NPNTATYFTNRALCYI 194

Query: 285 KMSNWQGAIDSCLEALEMDPSNTKALYRKAQGWQGLKEYDQALADLKKAQEIAPGDK 341
           K+ NW+ A   C  ALE+D +  K  +   Q    L  YD+A+  L KA ++A   K
Sbjct: 193 KLRNWELASQDCQRALELDRNLVKGHFFLGQALVELAMYDEAITHLMKAHDLAKDQK 23
>15093
          Length = 537

 Score = 51.6 bits (122), Expect = 6e-07,   Method: Compositional matrix adjust.
 Identities = 25/56 (44%), Positives = 33/56 (58%), Gaps = 1/56 (1%)
 Frame = +3

Query: 127 TNGSQFFITTVPTPHLDGKHVVFGQVIKGLGVARTLENVEVN-GEKPAKLCVIAEC 181
           TN SQFF T     HLDGKH VFG+++ G+     +E VEV+  +KP +   I  C
Sbjct: 3   TNKSQFFFTFRSARHLDGKHAVFGRLVGGIETLDAMEKVEVDKKDKPKEEIKIESC 170
>23338
          Length = 1062

 Score = 50.4 bits (119), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 25/58 (43%), Positives = 36/58 (62%), Gaps = 2/58 (3%)
 Frame = -1

Query: 126  NTNGSQFFITTVPTPHLDGKHVVFGQVIKGLGVARTLENVEVNGE--KPAKLCVIAEC 181
            +TNGSQFFIT  P+  LDGKHV FG+V+KG  + +T+  +    +   P +   I +C
Sbjct: 1062 DTNGSQFFITLGPSRFLDGKHVAFGKVLKGFTLLKTINRMGPGDDYTTPRRPVRIVDC 889
>32109
          Length = 576

 Score = 47.0 bits (110), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 25/63 (39%), Positives = 36/63 (57%)
 Frame = +2

Query: 293 IDSCLEALEMDPSNTKALYRKAQGWQGLKEYDQALADLKKAQEIAPGDKAIQAELLKVKQ 352
           I  C +AL + P+N KALY KAQ    + E++QA     +AQ +   +KAI   L ++ Q
Sbjct: 2   ITYCHKALALQPNNVKALYHKAQALHFMSEFEQARGVYLRAQRLDSTNKAIATSLKRLDQ 181

Query: 353 MIK 355
            IK
Sbjct: 182 DIK 190
>13072
          Length = 608

 Score = 35.8 bits (81), Expect(2) = 8e-05,   Method: Compositional matrix adjust.
 Identities = 20/56 (35%), Positives = 26/56 (46%)
 Frame = -3

Query: 30  GRIVLELFADIVPKTAENFRALCXXXXXXXXXXXXPLHFKGCPFHRIIKKFMIQGG 85
           G + +EL  D+VPKT ENF  LC              ++ G  FHR I+ F    G
Sbjct: 228 GPLNVELHCDMVPKTCENFIKLCASG-----------YYDGTIFHRSIRNFYHPRG 94

 Score = 27.7 bits (60), Expect(2) = 8e-05,   Method: Compositional matrix adjust.
 Identities = 14/24 (58%), Positives = 16/24 (66%)
 Frame = -1

Query: 80  FMIQGGDFSNQNGTGGESIYGEKF 103
           F+IQGGD     G GGES +GE F
Sbjct: 110 FIIQGGD-PTGTGRGGESSWGEAF 42
>21265
          Length = 579

 Score = 32.0 bits (71), Expect = 0.44,   Method: Compositional matrix adjust.
 Identities = 21/54 (38%), Positives = 25/54 (46%)
 Frame = -3

Query: 29  VGRIVLELFADIVPKTAENFRALCXXXXXXXXXXXXPLHFKGCPFHRIIKKFMI 82
           +G I  +LFA   PKT ENF   C              +F    FHR+IK FMI
Sbjct: 130 MGDIQCKLFAKECPKTVENF---CVHSRNS--------YFNNHVFHRVIKGFMI 2
>19619
          Length = 577

 Score = 31.2 bits (69), Expect = 0.72,   Method: Compositional matrix adjust.
 Identities = 17/50 (34%), Positives = 28/50 (56%)
 Frame = +3

Query: 284 LKMSNWQGAIDSCLEALEMDPSNTKALYRKAQGWQGLKEYDQALADLKKA 333
           + +  +Q AI+S  +ALEM P +   L  +A+ +  L   + ALAD + A
Sbjct: 201 VHVKQYQRAIESFTKALEMKPGDKTCLVARAKCFLNLGNSEAALADSESA 350
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|27734986|ref|NP_663517.2| S-adenosylhomocysteine
hydrolase-like 1 [Mus musculus]
         (530 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

18254                                                                 294   8e-80
18314                                                                 201   6e-52
07987                                                                 106   2e-23
25186                                                                  52   5e-07
18083                                                                  28   7.3  
28054                                                                  28   8.4  
>18254
          Length = 928

 Score =  294 bits (752), Expect = 8e-80,   Method: Compositional matrix adjust.
 Identities = 149/295 (50%), Positives = 200/295 (67%), Gaps = 1/295 (0%)
 Frame = +3

Query: 219 DGWQANMILDDGGDLTHWVYKKYPNVFKKIRGIVEESVTGVHRLYQLSKAGKLCVPAMNV 278
           +G   NMILDDGGDLT+ V++KYP     I+G+ EE+ TGVH LY++    KL VPA+NV
Sbjct: 42  NGQPLNMILDDGGDLTNLVHEKYPQYLAGIKGLSEETTTGVHNLYRMMAEKKLKVPAINV 221

Query: 279 NDSVTKQKFDNLYCCRESILDGLKRTTDVMFGGKQVVVCGYGEVGKGCCAALKALGAIVY 338
           NDSVTK KFDNLY CRES++DG+KR TDVM  GK  VV GYG+VGKGC  AL+A GA V 
Sbjct: 222 NDSVTKSKFDNLYGCRESLVDGIKRATDVMLAGKVAVVAGYGDVGKGCAQALRAFGARVI 401

Query: 339 ITEIDPICALQACMDGFRVVKLNEVIRQVDVVITCTGNKNVVTREHLDRMKNSCIVCNMG 398
           ITEIDPI ALQA M+G+ V  +++ + +  + +T TG K ++  +H + M    I+CN+G
Sbjct: 402 ITEIDPINALQAAMEGYEVSTIDDSLSEARIFVTATGCKGILRPKHFENMLEDTIICNIG 581

Query: 399 HSNTEIDVTSLRTPELTWERVRSQVDHVIWPDGKRVVLLAEGRLLNLSCST-VPTFVLSI 457
           H + EID+  L     + E V+ QV+      G+ +++LAEGRL+NL C+   P+FV+S 
Sbjct: 582 HFDCEIDIAWLNDNCRSKEVVQPQVERYTMKSGRHLIVLAEGRLVNLGCAHGHPSFVMSN 761

Query: 458 TATTQALALIELYNAPEGRYKQDVYLLPKKMDEYVASLHLPSFDAHLTELTDDQA 512
           + T Q LA IEL+     +Y   V++LPKK+DE VA+LHL      LT+L DDQA
Sbjct: 762 SFTNQVLAQIELWTKTS-QYVLGVHMLPKKLDEEVAALHLSHLGVKLTKLDDDQA 923
>18314
          Length = 475

 Score =  201 bits (511), Expect = 6e-52,   Method: Compositional matrix adjust.
 Identities = 93/141 (65%), Positives = 109/141 (77%)
 Frame = -3

Query: 100 KGSSNFCVKNIKQAEFGRREIEIAEQDMSALISLRKRAQGEKPLAGAKIVGCTHITAQTA 159
           +GS  F  +NI+   FGRREIEIAEQ+M  L++LRKRA+G+KPL GAKI+GCTHITAQTA
Sbjct: 425 QGSW*FLRQNIEHNAFGRREIEIAEQEMPGLMALRKRAEGDKPLHGAKIIGCTHITAQTA 246

Query: 160 VLIETLCALGAQCRWSACNIYSTQNEXXXXXXXXXXXXXXWKGESEDDFWWCIDRCVNMD 219
           VL+ETL ALGA  RW+ACNIYSTQNE              WKGE+E+DFWWCIDRC+N +
Sbjct: 245 VLVETLVALGATVRWAACNIYSTQNEVAAALAESGICIFAWKGETEEDFWWCIDRCINAE 66

Query: 220 GWQANMILDDGGDLTHWVYKK 240
           GWQ NMILDDGGD TH + KK
Sbjct: 65  GWQPNMILDDGGDATHLMLKK 3
>07987
          Length = 1227

 Score =  106 bits (265), Expect = 2e-23,   Method: Compositional matrix adjust.
 Identities = 61/137 (44%), Positives = 85/137 (62%), Gaps = 8/137 (5%)
 Frame = -2

Query: 402  TEIDVTSLRTPELTWER-------VRSQVDHVIWPDGKRVVLLAEGRLLNLSCST-VPTF 453
            T + V + R  +LTW         V+ QV+      G+ +++LAEGRL+NL C+   P+F
Sbjct: 1187 TALSVHNYRH-DLTWRPRSI*PVVVQPQVERYTMKSGRHLIVLAEGRLVNLGCAHGHPSF 1011

Query: 454  VLSITATTQALALIELYNAPEGRYKQDVYLLPKKMDEYVASLHLPSFDAHLTELTDDQAK 513
            V+S + T Q LA IEL+     +Y   V++LPKK+DE VA+LHL      LT+L DDQA 
Sbjct: 1010 VMSNSFTNQVLAQIELWTK-TSQYVLGVHMLPKKLDEEVAALHLSHLGVKLTKLDDDQAT 834

Query: 514  YLGLNKNGPFKPNYYRY 530
            YLG+   GPFKP++YRY
Sbjct: 833  YLGIPAAGPFKPDHYRY 783
>25186
          Length = 1389

 Score = 52.4 bits (124), Expect = 5e-07,   Method: Compositional matrix adjust.
 Identities = 23/25 (92%), Positives = 25/25 (100%)
 Frame = +3

Query: 464 LALIELYNAPEGRYKQDVYLLPKKM 488
           LALIEL+NAP+GRYKQDVYLLPKKM
Sbjct: 3   LALIELFNAPQGRYKQDVYLLPKKM 77
>18083
          Length = 865

 Score = 28.5 bits (62), Expect = 7.3,   Method: Compositional matrix adjust.
 Identities = 14/53 (26%), Positives = 24/53 (45%)
 Frame = +1

Query: 353 DGFRVVKLNEVIRQVDVVITCTGNKNVVTREHLDRMKNSCIVCNMGHSNTEID 405
           D   V++++  +  V V+  CT   +   R    R +     C MG +NTE+ 
Sbjct: 589 DRMAVIRVSRTLTTVWVMCPCTTRSSTSARARTCRGEWGRAACTMGKANTEMT 747
>28054
          Length = 1341

 Score = 28.1 bits (61), Expect = 8.4,   Method: Compositional matrix adjust.
 Identities = 10/27 (37%), Positives = 16/27 (59%)
 Frame = -1

Query: 151  CTHITAQTAVLIETLCALGAQCRWSAC 177
            C H+  Q    ++TLC+L  +  W+AC
Sbjct: 1266 CAHLLDQPGTSVQTLCSLWWRVAWTAC 1186
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|21313080|ref|NP_080305.1| glyoxalase domain
containing 4 [Mus musculus]
         (298 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

19341                                                                 292   1e-79
12266                                                                 142   2e-35
38446                                                                  27   9.2  
>19341
          Length = 863

 Score =  292 bits (747), Expect = 1e-79,   Method: Compositional matrix adjust.
 Identities = 138/244 (56%), Positives = 187/244 (76%), Gaps = 2/244 (0%)
 Frame = -3

Query: 54  SKTMVGFGPEDDHFVAELTYNYGIGDYKLGNDFMGITLASSQAVSNARKLEWPLSKVAEG 113
           SK+MVG+GPED HFV ELTYNYGIG Y+LGNDF GIT+ SS+ +  A   ++P+S+  +G
Sbjct: 861 SKSMVGYGPEDSHFVVELTYNYGIGSYRLGNDFRGITITSSEVLERALDKQYPVSE-EDG 685

Query: 114 IFETEAPGGYKFYLQDRSPSQ--SDPVLKVTLAVSDLQKSLNYWSNLLGMKIYEQDEEKQ 171
           +   ++P GYKF++   +P +   DPV KV+L+ SDL KS+ YWS L GM +Y  D+  +
Sbjct: 684 LKVLQSPDGYKFFV---APGKVDGDPVQKVSLSCSDLTKSVEYWSKLCGMTVYSSDD--K 520

Query: 172 RALLGYADNQCKLELQGIQGAVDHAAAFGRIAFSCPQKELPDIEDLMKRESHSILTPLVS 231
            ALLG+ ++QCKLEL  + G V+HA AFGR+AF+CP+++LP ++  M+   H++LTPL+S
Sbjct: 519 TALLGFGZDQCKLELVAVDGKVEHATAFGRVAFACPREQLPSLQKSMEDSGHTVLTPLLS 340

Query: 232 LDTPGKATVQVVILADPDGHEICFVGDEAFRELSKMDPKGSKLLDDAMEADKSDEWFATR 291
           LDTPGKATV+VVILADPD HEICFVGD AFRELS++DPK  +LLD+A++ DKSD+WFA +
Sbjct: 339 LDTPGKATVEVVILADPDDHEICFVGDAAFRELSQVDPKADELLDEAIKNDKSDDWFAKK 160

Query: 292 NKPK 295
            + K
Sbjct: 159 GRTK 148
>12266
          Length = 996

 Score =  142 bits (358), Expect(2) = 2e-35,   Method: Compositional matrix adjust.
 Identities = 68/136 (50%), Positives = 90/136 (66%)
 Frame = +2

Query: 22  FFRDVLGMQVLRHEEFEEGCKAACYGPYDGKWSKTMVGFGPEDDHFVAELTYNYGIGDYK 81
           FFR++LGMQVLRHEEF+EGC A C GPYD +WSKTMVG+GPE+ HFV ELTYNYG+  Y+
Sbjct: 53  FFRNILGMQVLRHEEFKEGCDAECNGPYDNRWSKTMVGYGPEESHFVIELTYNYGVKSYE 232

Query: 82  LGNDFMGITLASSQAVSNARKLEWPLSKVAEGIFETEAPGGYKFYLQDRSPSQSDPVLKV 141
           +GNDF GIT+ S   +  A K  +P++K  E    T +P G+KF L  R+ S   P  ++
Sbjct: 233 MGNDFGGITIHSKDILPRAAKHSYPVTKHRESNILT-SPDGFKFTLLTRNRSIQIPYSRL 409

Query: 142 TLAVSDLQKSLNYWSN 157
           +      +   N  +N
Sbjct: 410 SCMSVTWKPHANTGTN 457

 Score = 24.3 bits (51), Expect(2) = 2e-35,   Method: Compositional matrix adjust.
 Identities = 9/12 (75%), Positives = 11/12 (91%)
 Frame = +3

Query: 5  RALHFVFKVKNR 16
          RALH+VFK+ NR
Sbjct: 3  RALHYVFKIGNR 38

 Score = 75.1 bits (183), Expect(2) = 3e-29,   Method: Compositional matrix adjust.
 Identities = 34/59 (57%), Positives = 44/59 (74%)
 Frame = +3

Query: 218 MKRESHSILTPLVSLDTPGKATVQVVILADPDGHEICFVGDEAFRELSKMDPKGSKLLD 276
           + +   +IL PL+ LDTPGKA+V V+ILADPDGHEICFV +E F ELS++D  G   L+
Sbjct: 627 VTKAGGTILKPLIKLDTPGKASVTVLILADPDGHEICFVDEEGFTELSQLDSDGDAQLN 803

 Score = 70.9 bits (172), Expect(2) = 3e-29,   Method: Compositional matrix adjust.
 Identities = 36/82 (43%), Positives = 49/82 (59%)
 Frame = +1

Query: 126 YLQDRSPSQSDPVLKVTLAVSDLQKSLNYWSNLLGMKIYEQDEEKQRALLGYADNQCKLE 185
           Y+ D+     DPV +V L VSDL+ S  YW+ LLGMK+ ++DE      L Y DNQ  L 
Sbjct: 361 YIVDQKSVNPDPVQQVELHVSDLEASRKYWNELLGMKLIKRDES---LWLSYGDNQATLR 531

Query: 186 LQGIQGAVDHAAAFGRIAFSCP 207
           L  +   ++ A A+GRIAF+ P
Sbjct: 532 LTHLSEPLNRAKAYGRIAFAVP 597
>38446
          Length = 1526

 Score = 26.9 bits (58), Expect = 9.2,   Method: Compositional matrix adjust.
 Identities = 15/35 (42%), Positives = 19/35 (54%)
 Frame = +1

Query: 173 ALLGYADNQCKLELQGIQGAVDHAAAFGRIAFSCP 207
            +LG    + K++L  IQG   H   FGR AF CP
Sbjct: 928 VILGLHGRRVKVKLLRIQG---HFHPFGRSAFLCP 1023
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|21553309|ref|NP_659146.1| apolipoprotein A-I binding
protein [Mus musculus]
         (282 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

16876                                                                 233   1e-79
>16876
          Length = 2281

 Score =  233 bits (593), Expect(2) = 1e-79,   Method: Compositional matrix adjust.
 Identities = 117/206 (56%), Positives = 144/206 (69%), Gaps = 3/206 (1%)
 Frame = +3

Query: 21  RVISQQSVCRARPIWWGTQRRGSETMAGA-AVKYLSQEEAQAVDQELFNEYQFSVDQLME 79
           R   ++  C +R I     RR   TMA A  V+YL QEEAQ +D+ELF+ Y FSVDQLME
Sbjct: 72  RQTQRRLSCLSRHITSPCARR---TMATAPTVRYLGQEEAQKIDEELFSTYAFSVDQLME 242

Query: 80  LAGLSCATAIAKAYPPTSMSKSPPTVLVICGPGNNGGDGLVCARHLKLFGYQPTIYYPKR 139
           LAG SCA A+AK YP  S++     VLV CGPGNNGGDGLVCARHLKLFGY P+I+YPK+
Sbjct: 243 LAGYSCAVAVAKCYPAHSLTTHQGAVLVCCGPGNNGGDGLVCARHLKLFGYTPSIFYPKQ 422

Query: 140 PNKPLFTGLVTQCQKMDIPFLGEMPPEPMMVDELYELVVDAIFGFSFKGDVREPFHSILS 199
            +K LF  L TQCQKM++ F+  +P +P  +   Y+L+VDA+FGFSFKG  R  F  IL 
Sbjct: 423 SSKQLFLNLKTQCQKMNVAFVDTLPSDPATLTTTYDLIVDALFGFSFKGPARPMFAEILE 602

Query: 200 VLSGL--TVPIASIDIPSGWDVEKGN 223
            L  +   VPI SID+PSGWDVE+G+
Sbjct: 603 KLKKVENDVPICSIDVPSGWDVEEGS 680

 Score = 82.0 bits (201), Expect(2) = 1e-79,   Method: Compositional matrix adjust.
 Identities = 38/62 (61%), Positives = 44/62 (70%)
 Frame = +1

Query: 220 EKGNPSGIQPDLLISLTAPKKSATHFTGRYHYLGGRFVPPALEKKYQLNLPSYPDTECVY 279
            +G   G+QP LLISLTAPKK A HF G +H LGGRFVP +L  KY L LP YPDT+ + 
Sbjct: 670 RRGVAEGLQPKLLISLTAPKKCAVHFRGPHHILGGRFVPQSLADKYDLRLPEYPDTDAIV 849

Query: 280 RL 281
           RL
Sbjct: 850 RL 855
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|33942081|ref|NP_898837.1| CDC42 binding protein
kinase beta [Mus musculus]
         (1713 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

03240                                                                 295   1e-79
19704                                                                 112   9e-43
30755                                                                 130   4e-30
18484                                                                 103   5e-27
31885                                                                 114   3e-25
17932                                                                  79   1e-24
27590                                                                 111   3e-24
15910                                                                  97   8e-20
27405                                                                  96   9e-20
00300                                                                  94   4e-19
12721                                                                  92   1e-18
14420                                                                  92   2e-18
01707                                                                  92   2e-18
09606                                                                  90   8e-18
00486                                                                  89   2e-17
26560                                                                  84   5e-16
12786                                                                  82   2e-15
18921                                                                  80   1e-14
13212                                                                  79   1e-14
01392                                                                  79   1e-14
13592                                                                  78   3e-14
01060                                                                  74   5e-13
14126                                                                  71   4e-12
18663                                                                  69   2e-11
17722                                                                  67   4e-11
01718                                                                  67   4e-11
13066                                                                  67   7e-11
26156                                                                  66   1e-10
16708                                                                  66   1e-10
19094                                                                  65   2e-10
17975                                                                  64   6e-10
06405                                                                  63   1e-09
25445                                                                  62   2e-09
26711                                                                  62   2e-09
33586                                                                  52   6e-09
21079                                                                  59   2e-08
04591                                                                  58   4e-08
35187                                                                  58   4e-08
19761                                                                  57   7e-08
00715                                                                  57   1e-07
11185                                                                  56   1e-07
19361                                                                  55   2e-07
25019                                                                  55   2e-07
01966                                                                  55   2e-07
00392                                                                  54   4e-07
21433                                                                  54   5e-07
01756                                                                  54   7e-07
03508                                                                  53   1e-06
29581                                                                  51   4e-06
17591                                                                  38   4e-06
27546                                                                  49   2e-05
20152                                                                  48   3e-05
17300                                                                  47   5e-05
12672                                                                  46   1e-04
14116                                                                  45   3e-04
28638                                                                  44   5e-04
37063                                                                  43   0.001
11353                                                                  43   0.001
21808                                                                  42   0.002
29590                                                                  42   0.002
04852                                                                  42   0.002
22804                                                                  42   0.003
18996                                                                  42   0.003
01431                                                                  42   0.003
27274                                                                  41   0.004
04138                                                                  41   0.005
07833                                                                  40   0.006
38560                                                                  40   0.006
32957                                                                  40   0.006
37602                                                                  40   0.008
32359                                                                  31   0.015
07836                                                                  39   0.016
28157                                                                  39   0.018
20640                                                                  39   0.021
15105                                                                  38   0.042
07291                                                                  37   0.057
26009                                                                  37   0.059
19301                                                                  37   0.067
18481                                                                  36   0.10 
02638                                                                  36   0.12 
09007                                                                  35   0.18 
01106                                                                  35   0.23 
07940                                                                  35   0.28 
00638                                                                  35   0.39 
17516                                                                  34   0.48 
31489                                                                  34   0.51 
18401                                                                  34   0.54 
11780                                                                  33   0.92 
09986                                                                  33   1.1  
06101                                                                  32   2.0  
37902                                                                  32   2.1  
29360                                                                  31   4.7  
30339                                                                  30   6.4  
11404                                                                  30   8.7  
09344                                                                  30   9.4  
>03240
          Length = 1683

 Score =  295 bits (755), Expect = 1e-79,   Method: Compositional matrix adjust.
 Identities = 156/365 (42%), Positives = 214/365 (58%), Gaps = 52/365 (14%)
 Frame = -3

Query: 76   FEIIKVIGRGAFGEVAVVKMRNTERIYAMKILNKWEMLKRAETACFREERDVLVNGDCQW 135
            FE IK +G GAFGEV++ +  +T  +YAMK L K ++LKR + A  + ERD+L   D +W
Sbjct: 1285 FEKIKTLGVGAFGEVSLCRKNDTGMLYAMKTLRKSDVLKRNQVAHVKAERDILAEADNEW 1106

Query: 136  ITALHYAFQDENYLYLVMDYYVGGDLLTLLSKFEDKLPEDMARFYIGEMVLAIDSIHQLH 195
            +  L+Y+FQD NYLY VMDY  GGDL+ LL + E  L E +ARFY+ E+V AI+S+H++ 
Sbjct: 1105 VVKLYYSFQDHNYLYFVMDYVPGGDLMGLLIRME-ILDEPLARFYVAELVQAIESVHRMG 929

Query: 196  YVHRDIKPDNVLLDVNGHIRLADFGSCLKM---------NDDGT---------------- 230
            ++HRDIKPDN+L+D NGHI+L DFG C              DGT                
Sbjct: 928  FIHRDIKPDNILIDRNGHIKLTDFGLCTGFRWTHNSKYYQRDGTHARQDSMEVKCQLDEQ 749

Query: 231  ---------------VQSSVA---VGTPDYISPEILQAMEDGMGKYGPECDWWSLGVCMY 272
                            Q  +A   VGTP+YI+PE+L      +G Y   CDWWS+GV ++
Sbjct: 748  CQCEILKPLERRRKREQRCLAHSLVGTPNYIAPEVLSR----LGGYTSVCDWWSVGVILF 581

Query: 273  EMLYGETPFYAESLVETYGKIMNHEERFQFPSHVTDVSEEAKDLIQRLICSRERRLGQNG 332
            EML G  PFYA +  ET  K++N ++  + P   +++S+ AKDLI RL C  + RLG NG
Sbjct: 580  EMLVGHPPFYANTPAETQYKVINWKDMLKIPRE-SNLSQPAKDLILRLCCGSDDRLGLNG 404

Query: 333  IEDFKKHAFFEGLNWENIRNLEAPYIPDVSSPSDTSNFD-VDDDMLRN--------IEIL 383
              + K H FF G+N+E +R  + PY+P++   +DTSNFD VD D LRN        +E L
Sbjct: 403  AGEIKTHMFFAGVNFETLRKQQPPYVPNIRYATDTSNFDPVDPDKLRNSDSEENKKVEKL 224

Query: 384  PPGSH 388
              G H
Sbjct: 223  ENGKH 209
>19704
          Length = 804

 Score =  112 bits (279), Expect(2) = 9e-43,   Method: Compositional matrix adjust.
 Identities = 68/174 (39%), Positives = 94/174 (54%), Gaps = 12/174 (6%)
 Frame = -1

Query: 1454 GRRSRMQELMWPAAPVACSCSPTHVTVYSEYGVDVFDVRTMEWVQTIGLRRIRPLNSDGS 1513
            G RSRMQE++WP+ P+A S S  ++  Y+E    VF+V T EW+QT+ L+R +PL  +GS
Sbjct: 576  GERSRMQEILWPSQPIALSYSSPYLICYAENSTFVFNVDTAEWLQTMCLKRTKPLCKNGS 397

Query: 1514 LNLL-GCEPPRLIYFKNKFS-GTILNVPDTSDNSKKQMLRTRSKRRFVFKVPXXXXXXXX 1571
            L LL   +   +I+ K   +    L V +   N       +R+KRRF FK          
Sbjct: 396  LCLLSSVDTQHIIFLKTLHTEEDQLAVAEIFKNKS-----SRNKRRFSFK---SREDERS 241

Query: 1572 XXXXXDPEL----------RSKMISNPTNFNHVAHMGPGDGMQVLMDLPLSAAP 1615
                 D  L          RS++IS P+NF+H+AHMGP  GMQVL+DLP    P
Sbjct: 240  SNKRGDKALREKHGSVGDRRSRIISPPSNFSHIAHMGPDQGMQVLIDLPKQQKP 79

 Score = 82.4 bits (202), Expect(2) = 9e-43,   Method: Composition-based stats.
 Identities = 42/79 (53%), Positives = 53/79 (67%)
 Frame = -2

Query: 1377 HVQWMAVFKDRLCVGYPSGFSLLSIQGDGPPLDLVNPTDPSLAFLSQQSFDALCAVELKS 1436
             VQ M +  +RLCVGYPS F++ S+QGD PPL LVN  D +L FL Q   +A+ AVEL S
Sbjct: 803  QVQCMEMMGERLCVGYPSCFAIYSMQGDAPPLSLVNTDDRTLRFL-QTPVEAMLAVELAS 627

Query: 1437 EEYLLCFSHMGLYVDPQGR 1455
             E+ L F+ +GLYV  Q R
Sbjct: 626  GEFXLLFNVVGLYVKKQER 570
>30755
          Length = 1137

 Score =  130 bits (328), Expect = 4e-30,   Method: Compositional matrix adjust.
 Identities = 77/217 (35%), Positives = 123/217 (56%), Gaps = 5/217 (2%)
 Frame = +2

Query: 174 EDMARFYIGEMVLAIDSIHQLHYVHRDIKPDNVLLDVNGHIRLADFGSCLKMNDDGTVQS 233
           E+  RFY  E++ A+  +H    ++RD+K +N+LLD +GHI++ADFG C +    G    
Sbjct: 29  EERTRFYGAEIISALGYLHSQGIIYRDLKLENLLLDKDGHIKVADFGLCKEDITYGRTTK 208

Query: 234 SVAVGTPDYISPEILQAMEDGMGKYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKI 293
           +   GTP+Y++PE+L   +     YG   DWW  GV MYEM+ G  PFY       +  I
Sbjct: 209 TFC-GTPEYLAPEVLDDND-----YGRAVDWWGTGVVMYEMICGRLPFYNRDHDVLFTLI 370

Query: 294 MNHEERFQFPSHVTDVSEEAKDLIQRLICSRER-RL--GQNGIEDFKKHAFFEGLNWENI 350
           +   E  +FP ++TD   EAK L+  L+    R RL  GQ+ +++ + H FF  +NW ++
Sbjct: 371 L--VEDVKFPRNITD---EAKSLLSGLLAKDPRNRLGGGQDDVKEIQAHPFFASINWTDL 535

Query: 351 --RNLEAPYIPDVSSPSDTSNFDVDDDMLRNIEILPP 385
             + +  P+ P V+S +DT  FD ++    ++E+ PP
Sbjct: 536 VQKKITPPFKPQVTSDTDTRYFD-EEFTGESVELTPP 643
>18484
          Length = 635

 Score =  103 bits (256), Expect(2) = 5e-27,   Method: Compositional matrix adjust.
 Identities = 60/162 (37%), Positives = 85/162 (52%), Gaps = 1/162 (0%)
 Frame = +1

Query: 169 EDKLPEDMARFYIGEMVLAIDSIHQLHYVHRDIKPDNVLLDVNGHIRLADFGSCLKMNDD 228
           E K  E +A FY  E+ + +  +H    ++RD+K DNV+LD  GHI++ADFG C K    
Sbjct: 25  EGKFKEPVAAFYAAEIAVGLFFLHDQGIIYRDLKLDNVMLDSEGHIKIADFGMC-KEGMT 201

Query: 229 GTVQSSVAVGTPDYISPEILQAMEDGMGKYGPECDWWSLGVCMYEMLYGETPFYAESLVE 288
           G   +    GTPDYI+PEI+         Y    DWW+ GV ++EML G+ PF  E   E
Sbjct: 202 GDATTRTFCGTPDYIAPEIVLYQ-----PYSKSVDWWAYGVLLFEMLAGQPPFDGEDEDE 366

Query: 289 TYGKIMNHEERFQFPSHVTDVSEEAKDLIQRLICSR-ERRLG 329
            +  I +H       S+   +S EA  L + L+     +RLG
Sbjct: 367 LFSSITDHNV-----SYPKAMSREAVSLCKGLLMKNPTKRLG 477

 Score = 38.1 bits (87), Expect(2) = 5e-27,   Method: Composition-based stats.
 Identities = 17/44 (38%), Positives = 25/44 (56%), Gaps = 2/44 (4%)
 Frame = +2

Query: 330 QNGIEDFKKHAFFEGLNWENIRNLEA--PYIPDVSSPSDTSNFD 371
           QNG  D + HAFF  + W+ I+++E   PY P ++      NFD
Sbjct: 485 QNGERDIRDHAFFRRIVWDKIKSMEVQPPYKPKITDRRKAENFD 616
>31885
          Length = 529

 Score =  114 bits (285), Expect = 3e-25,   Method: Compositional matrix adjust.
 Identities = 62/160 (38%), Positives = 90/160 (56%)
 Frame = -2

Query: 126 DVLVNGDCQWITALHYAFQDENYLYLVMDYYVGGDLLTLLSKFEDKLPEDMARFYIGEMV 185
           D+L   D  ++  L YAFQDE  L++V+D ++GGDL   + + E    ED  +FY+ ++ 
Sbjct: 516 DMLTRLDHPFLVNLWYAFQDEEDLFMVVDLFLGGDLRYHMQQ-EVSFREDCVKFYLCQLA 340

Query: 186 LAIDSIHQLHYVHRDIKPDNVLLDVNGHIRLADFGSCLKMNDDGTVQSSVAVGTPDYISP 245
           L +D +     VHRDIKPDN+LLD  GH  + DF    ++ DD    S+   GT  Y++P
Sbjct: 339 LVLDYLRSQKIVHRDIKPDNILLDEQGHCHVTDFNIATQLEDDELATST--SGTRPYMAP 166

Query: 246 EILQAMEDGMGKYGPECDWWSLGVCMYEMLYGETPFYAES 285
           E+     +    YG   DWWSLGV ++E+L    PF   S
Sbjct: 165 EVYGVAINERRGYGFPVDWWSLGVSLFELLKKRRPFSVHS 46
>17932
          Length = 597

 Score = 79.3 bits (194), Expect(2) = 1e-24,   Method: Compositional matrix adjust.
 Identities = 44/105 (41%), Positives = 64/105 (60%), Gaps = 2/105 (1%)
 Frame = -3

Query: 301 QFPSHVTDVSEEAKDLIQRLICSRERRLGQNGIEDFKKHAFFEGLNWENIRNLEAPYIPD 360
           Q P H + VS+EA+DLI +L+   + RLG     + ++H FF+ ++W NIRN   PY+P 
Sbjct: 481 QVPPH-SSVSKEARDLISQLLSDGKSRLGW---PELQQHPFFKTVDWANIRNAMPPYVPS 314

Query: 361 VSSPSDTSNFDVDDDM--LRNIEILPPGSHTGFSGLHLPFIGFTF 403
           +SS  DTS+FD  +      NI+     S   F+G HLPF+GFT+
Sbjct: 313 ISSLDDTSHFDEVEKARPAPNIDSFHQPSSRDFTGRHLPFVGFTY 179

 Score = 54.3 bits (129), Expect(2) = 1e-24,   Method: Composition-based stats.
 Identities = 24/44 (54%), Positives = 29/44 (65%), Gaps = 2/44 (4%)
 Frame = -2

Query: 264 WWSLGVCMYEMLYGETPFYAE--SLVETYGKIMNHEERFQFPSH 305
           WWSLGVC YEML+G TPF  +  S+V TY  IMN++     PS 
Sbjct: 596 WWSLGVCAYEMLFGCTPFTDDDGSMVATYNNIMNYKTNSSSPSQ 465
>27590
          Length = 544

 Score =  111 bits (277), Expect = 3e-24,   Method: Compositional matrix adjust.
 Identities = 69/179 (38%), Positives = 97/179 (54%), Gaps = 5/179 (2%)
 Frame = -1

Query: 1448 LYVDPQGRRSRMQELMWPAAPVACS-CSPTHVTVYSEYGVDVFDVRTMEWVQTIGLRRIR 1506
            LYV   G RSR QE++WP+ P+A S CSP ++  Y+E    VF+V+T EW+QT+ L++ R
Sbjct: 544  LYVKRSGERSRSQEILWPSQPLALSYCSP-YLVCYAENSTFVFNVQTAEWLQTMCLKKTR 368

Query: 1507 PLNSDGSLNLLGC-EPPRLIYFKNKFSGTILNVPDTSDNSKKQMLRTRSKRRFVFKVPXX 1565
            PL  DGSL LL   +   +I+ KN            +D  +  +      R    K    
Sbjct: 367  PLCKDGSLCLLSAFDTQHVIFLKNLH----------ADEDRLAVAEIFRXRNSRSKRRFS 218

Query: 1566 XXXXXXXXXXXDPELRSKMISNPTNFNHVAHMGPGDGMQVLMDLPLSAA---PTVQEEK 1621
                         + RS++ISNP+NF+H+AHMGP  GMQVL+DLP   A   P +Q+ K
Sbjct: 217  FKSKEDERSGSKGDRRSRVISNPSNFSHIAHMGPDQGMQVLIDLPKQQAEGDPQLQKVK 41
>15910
          Length = 1361

 Score = 96.7 bits (239), Expect = 8e-20,   Method: Compositional matrix adjust.
 Identities = 57/151 (37%), Positives = 88/151 (58%), Gaps = 3/151 (1%)
 Frame = +2

Query: 174 EDMARFYIGEMVLAIDSIHQLHYVHRDIKPDNVLLDV---NGHIRLADFGSCLKMNDDGT 230
           +D AR  I +++  +  IH    VHRD+KP+N+L +    +  ++LADFG  L    +  
Sbjct: 464 KDAAR-AISDILHGVQYIHANGVVHRDLKPENLLYECMTDDSKLKLADFG--LSRIIEPE 634

Query: 231 VQSSVAVGTPDYISPEILQAMEDGMGKYGPECDWWSLGVCMYEMLYGETPFYAESLVETY 290
           VQ S   GTP Y +PE+L+       KY P  D WS+GV  Y +L G  PF+AE+  E Y
Sbjct: 635 VQMSTVCGTPGYCAPEVLKG-----DKYTPSVDMWSVGVIAYILLCGYEPFFAENEFEMY 799

Query: 291 GKIMNHEERFQFPSHVTDVSEEAKDLIQRLI 321
            KI+  E +F    + +++SE AKD++++L+
Sbjct: 800 RKIIKGEYKFD-EEYWSEISENAKDVVRKLL 889
>27405
          Length = 532

 Score = 96.3 bits (238), Expect = 9e-20,   Method: Compositional matrix adjust.
 Identities = 63/185 (34%), Positives = 97/185 (52%), Gaps = 5/185 (2%)
 Frame = -3

Query: 86  AFGEVAVVKMRNTERIYAMKILNKWEM-LKRAETACFREE--RDVLVNGDCQ-WITALHY 141
            FGEV   +  +T ++YAMK L+K  + +K  ET    E     ++  G+   +I  + Y
Sbjct: 530 GFGEVYGCRKADTGKMYAMKCLDKKRIKMKGGETLALNERIMLSLVSTGEGSPFIVCMTY 351

Query: 142 AFQDENYLYLVMDYYVGGDLLTLLSKFEDKLPEDMARFYIGEMVLAIDSIHQLHYVHRDI 201
           AFQ    L  ++D   GGDL   LS+      E   RFY  E++L ++ +H    V+RD+
Sbjct: 350 AFQTPEKLCFILDLMNGGDLHYHLSQ-HGVFTEKEVRFYAAEVMLGLEHMHSRFVVYRDL 174

Query: 202 KPDNVLLDVNGHIRLADFG-SCLKMNDDGTVQSSVAVGTPDYISPEILQAMEDGMGKYGP 260
           KP N+LLD NGH+R++D G +C    D    +   +VGT  Y++PE+L   +     Y  
Sbjct: 173 KPANILLDENGHVRISDLGLAC----DFSKKKPHASVGTHGYMAPEVLMKGQ----AYDS 18

Query: 261 ECDWW 265
             DW+
Sbjct: 17  SADWF 3
>00300
          Length = 2318

 Score = 94.4 bits (233), Expect = 4e-19,   Method: Compositional matrix adjust.
 Identities = 70/244 (28%), Positives = 117/244 (47%), Gaps = 3/244 (1%)
 Frame = -1

Query: 82   IGRGAFGEVAVVKMRNTERIYAMKILN-KWEMLKRAETACFREERDVLVNGDCQWITALH 140
            IG G FG+V      +T  + A+K +  +   L++    C  +E  +      + +   +
Sbjct: 1634 IGEGQFGKVYTAVNMSTGELMALKEMKFQPNDLQQLREMC--DEIKIFEGIQHENLVKYY 1461

Query: 141  YAFQDENYLYLVMDYYVGGDLLTLLSKFEDKLPEDMARFYIGEMVLAIDSIHQLHYVHRD 200
                 ++ + + M+Y    D  T+    +  LPE + R Y  E+VLA++ +H+   VHRD
Sbjct: 1460 GVEVHKDEMLMFMEYC---DTGTIEEAAKMGLPEYLIRRYTREIVLAVNHLHENSIVHRD 1290

Query: 201  IKPDNVLLDVNGHIRLADFGSCLKMNDDGTVQSSVA--VGTPDYISPEILQAMEDGMGKY 258
            IK  N+ L  NGH++L DFG  +K+    T+       VGT  Y++PE+    ++  G Y
Sbjct: 1289 IKGANIFLTSNGHVKLGDFGCSVKLKSHTTMPGEFHNLVGTTAYMAPEVF--TQNDQGGY 1116

Query: 259  GPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHEERFQFPSHVTDVSEEAKDLIQ 318
            G   D WSLG  + EM  G+ P++   L   Y +IM        P+    +S E K  + 
Sbjct: 1115 GRAADIWSLGCVVIEMATGKRPWH--DLDNNY-QIMYKVGIGHKPAVPDSLSVEGKHFLD 945

Query: 319  RLIC 322
             ++C
Sbjct: 944  LIMC 933
>12721
          Length = 821

 Score = 92.4 bits (228), Expect = 1e-18,   Method: Compositional matrix adjust.
 Identities = 58/212 (27%), Positives = 110/212 (51%)
 Frame = +1

Query: 82  IGRGAFGEVAVVKMRNTERIYAMKILNKWEMLKRAETACFREERDVLVNGDCQWITALHY 141
           IG G+ G V +   R+  ++     + K ++ K+        E  V+ +     I  ++ 
Sbjct: 112 IGEGSTGIVCIATSRDGRQMA----VKKMDLRKQQRRELLFNEVVVMRDYHHPNIVEMYN 279

Query: 142 AFQDENYLYLVMDYYVGGDLLTLLSKFEDKLPEDMARFYIGEMVLAIDSIHQLHYVHRDI 201
           ++   + L++VM++  GG L  +++   +++ E          + A+  +H    +HRDI
Sbjct: 280 SYLVNDELWVVMEFMEGGALTDIVTN--NRMDEVQIATVCRACLKALAFLHANGVIHRDI 453

Query: 202 KPDNVLLDVNGHIRLADFGSCLKMNDDGTVQSSVAVGTPDYISPEILQAMEDGMGKYGPE 261
           K D++LL  +G ++L DFG C ++  D   + S+ VGTP +++PE++  +      YGPE
Sbjct: 454 KSDSILLSHDGKVKLXDFGFCAQVTQDLQKRKSL-VGTPYWMAPEVISRL-----PYGPE 615

Query: 262 CDWWSLGVCMYEMLYGETPFYAESLVETYGKI 293
            D WSLG+ + EM+  E PF+ E  ++   +I
Sbjct: 616 VDIWSLGIMVMEMIDAEPPFFNEPPLQAMRRI 711
>14420
          Length = 528

 Score = 92.0 bits (227), Expect = 2e-18,   Method: Compositional matrix adjust.
 Identities = 48/137 (35%), Positives = 84/137 (61%)
 Frame = +2

Query: 149 LYLVMDYYVGGDLLTLLSKFEDKLPEDMARFYIGEMVLAIDSIHQLHYVHRDIKPDNVLL 208
           L++VM++  GG L  +++  E  + E        E + A++ +H+   +HRDIK DN+LL
Sbjct: 125 LWVVMEFLAGGSLTDVVT--ETCMDEGQIAAVCRECLQALEFLHENQVIHRDIKSDNILL 298

Query: 209 DVNGHIRLADFGSCLKMNDDGTVQSSVAVGTPDYISPEILQAMEDGMGKYGPECDWWSLG 268
            ++G ++L DFG C +++ + + +S++ VGTP +++PE++        +YGP  D WSLG
Sbjct: 299 GMDGSVKLTDFGFCAQLSPEQSKRSTM-VGTPYWMAPEVVTR-----KQYGPTVDIWSLG 460

Query: 269 VCMYEMLYGETPFYAES 285
           V   EM+ GE P+  E+
Sbjct: 461 VMCIEMIEGEPPYLNEN 511
>01707
          Length = 757

 Score = 91.7 bits (226), Expect = 2e-18,   Method: Compositional matrix adjust.
 Identities = 67/215 (31%), Positives = 109/215 (50%)
 Frame = +1

Query: 74  EDFEIIKVIGRGAFGEVAVVKMRNTERIYAMKILNKWEMLKRAETACFREERDVLVNGDC 133
           E +E I  IG G++G V   + + T ++ A+K   + E     +    RE R +L     
Sbjct: 64  EKYEKIGKIGEGSYGVVFKCRNKETSQLVAIKKFVESEDDPLIKKIAMREIR-MLKQLKH 240

Query: 134 QWITALHYAFQDENYLYLVMDYYVGGDLLTLLSKFEDKLPEDMARFYIGEMVLAIDSIHQ 193
             +  L   F+ +  L+LV DY V   LL  L ++   LPE M +  I + +LA++  HQ
Sbjct: 241 PNLVRLIEVFRRKKRLHLVFDY-VDHTLLNELDRYPRGLPEPMVKRIIYQTLLAVNFCHQ 417

Query: 194 LHYVHRDIKPDNVLLDVNGHIRLADFGSCLKMNDDGTVQSSVAVGTPDYISPEILQAMED 253
            + +HRD+KP+N+L+   G ++L DFG    +   G  + +  V T  Y +PE+L     
Sbjct: 418 YNTIHRDVKPENILITRQGQVKLCDFGFARILTGPGD-EYTDYVATRWYRAPELLV---- 582

Query: 254 GMGKYGPECDWWSLGVCMYEMLYGETPFYAESLVE 288
           G  +YGP  D W++G    E+L G+  +   S V+
Sbjct: 583 GDTQYGPPVDVWAIGCVFAELLTGQALWPGRSDVD 687
>09606
          Length = 1300

 Score = 90.1 bits (222), Expect = 8e-18,   Method: Compositional matrix adjust.
 Identities = 81/299 (27%), Positives = 131/299 (43%), Gaps = 28/299 (9%)
 Frame = -3

Query: 74   EDFEIIKVIGRGAFGEVAVVKMRNTERIYAMKILNKWEMLKRAE-TACFREERDVLVNGD 132
            E+F + + +G+G    +   + + T    A+  + K    KR E T   R   D+     
Sbjct: 1115 ENFVLYEELGKGEHSIIYKGRRKGTINFVAIHCIEK---CKRPEVTNTVRMTHDISHPNV 945

Query: 133  CQWITALHYAFQDENYLYLVMDYYVGGDLLTLLSKFEDKLPEDMARFYIGEMVLAIDSIH 192
             Q     H  ++  N+L+LV++   GG L  +L++ +  LPE   R +   +V  +  IH
Sbjct: 944  VQ----FHEWYETSNHLWLVVELCTGGSLADILAQ-DHHLPETSIRDFGIHLVTGLHYIH 780

Query: 193  QLHYVHRDIKPDNVLLDVNGHIRLADFG--------------SCLKMNDDGTVQSSVAV- 237
             L  +  D++P  VLLD +G ++ ADFG                 +  D   +QS+  + 
Sbjct: 779  SLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEAGDQWNIQSAEEMM 600

Query: 238  ------GTPDYISPEILQAMEDGMGKYGPECDWWSLGVCMYEMLYGETPFYAESLVETYG 291
                  G+P Y++PE+ Q  E  +       D W+LG   YEM  G  PF  E+   T  
Sbjct: 599  KQVPTSGSPTYMAPEVFQGAEPSI-----MSDLWALGCVFYEMFSGHPPFLGETYDITKD 435

Query: 292  KIMNHEERFQFPS-----HVTDVSEEAKDLIQRLIC-SRERRLGQNGIEDFKKHAFFEG 344
            K++N E  F  P           S E  +L++ L+     RRL    +    KHAF++G
Sbjct: 434  KVLNKE--FPLPKVKGSRLSAKPSPEFLNLLESLLQKDSTRRLSWASL---VKHAFWQG 273
>00486
          Length = 797

 Score = 88.6 bits (218), Expect = 2e-17,   Method: Compositional matrix adjust.
 Identities = 67/185 (36%), Positives = 93/185 (50%), Gaps = 7/185 (3%)
 Frame = -2

Query: 238 GTPDYISPEILQAMEDGMGKYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHE 297
           GT +Y++PEIL     G GK     DWWSLG  MY+ML G  PF AE+  +T  KI+  +
Sbjct: 772 GTIEYMAPEILT--RTGHGK---AVDWWSLGALMYDMLTGSPPFTAENRKKTIDKIL--K 614

Query: 298 ERFQFPSHVTDVSEEAKDLIQRLICSR-ERRLGQNGIED---FKKHAFFEGLNWE--NIR 351
            +   P ++T+   EA+ LI++L+      RLG  G +D    K H FF   NW    +R
Sbjct: 613 GKLNLPPYLTN---EARGLIKKLLRKNPAERLG-GGHDDSGPIKDHQFFRNTNWALLALR 446

Query: 352 NLEAPYIPDVSSPSDTSNFDVDDDMLRNIEILPPGSHTGFSGLHLPFIGFTFTTESCFSD 411
             E P+ P+V+S  DTS FD      R   +  P        ++  F GFT+   S   +
Sbjct: 445 RAEPPFRPNVTSDEDTSQFDT--KFTRQTPVDSPDDTILSDSINQVFKGFTYIAPSVLEE 272

Query: 412 -RGSL 415
             GSL
Sbjct: 271 VNGSL 257
>26560
          Length = 398

 Score = 84.0 bits (206), Expect = 5e-16,   Method: Compositional matrix adjust.
 Identities = 41/111 (36%), Positives = 64/111 (57%), Gaps = 1/111 (0%)
 Frame = -1

Query: 172 LPEDMARFYIGEMVLAIDSIHQLHYVHRDIKPDNVLLDVNGHIRLADFG-SCLKMNDDGT 230
             E   RFY  E++L ++ +H    V+RD+KP N+LLD NGH+R++D G +C    D   
Sbjct: 365 FTEKEVRFYAAEVMLGLEHMHSRFVVYRDLKPANILLDENGHVRISDLGLAC----DFSK 198

Query: 231 VQSSVAVGTPDYISPEILQAMEDGMGKYGPECDWWSLGVCMYEMLYGETPF 281
            +   +VGT  Y++PE+L   +     Y    DW+S G  +Y++L G +PF
Sbjct: 197 KRPHASVGTHGYMAPEVLMKGQ----SYDSSADWFSFGCMLYKLLKGHSPF 57
>12786
          Length = 460

 Score = 82.4 bits (202), Expect = 2e-15,   Method: Compositional matrix adjust.
 Identities = 51/132 (38%), Positives = 68/132 (51%), Gaps = 16/132 (12%)
 Frame = -3

Query: 166 SKFEDKLPEDMARFYIGEMVLAIDSIHQLHYVHRDIKPDNVLLDVNGHIRLADFGSCLKM 225
           +K E  L   M +FY  EM+ A+ ++H    +H D+KP N +L V G+++L DFG    +
Sbjct: 437 AKQEQGLDRMMIKFYWREMLRAVKALHNEGVIHSDLKPANFML-VAGNLKLIDFGIANTL 261

Query: 226 NDDGT-VQSSVAVGTPDYISPEILQAM----------EDGM-----GKYGPECDWWSLGV 269
             D T V     VGTP Y+SPE + A           EDG       K G   D WSLG 
Sbjct: 260 QQDKTSVLKDSRVGTPSYMSPEAIMAACDDSADDSMEEDGHRTKPKYKVGVRSDVWSLGC 81

Query: 270 CMYEMLYGETPF 281
            +Y M+YG TPF
Sbjct: 80  ILYNMVYGRTPF 45
>18921
          Length = 697

 Score = 79.7 bits (195), Expect = 1e-14,   Method: Compositional matrix adjust.
 Identities = 55/214 (25%), Positives = 106/214 (49%), Gaps = 2/214 (0%)
 Frame = +2

Query: 76  FEIIKVIGRGAFGEVAVVKMRNTERIYAMKILNKWEMLKRAETACFREERDVLVNGDCQW 135
           F+I+  +G G++G V     + T ++ A+K     ++    +     +E  ++   D ++
Sbjct: 35  FDILGKLGEGSYGSVFKSLHKETGQVLAIK-----QVPVDTDLQEIIKEISIMQQCDSKY 199

Query: 136 ITALHYAFQDENYLYLVMDYYVGGDLLTLLSKFEDKLPEDMARFYIGEMVLAIDSIHQLH 195
           I   + ++     L++VM+Y   G +  ++      L E      +   +  +  +H   
Sbjct: 200 IVKYYGSYFKNTDLWIVMEYCGAGSVSDIMRLRNKTLVEREIATILYYTLKGLXYLHSRR 379

Query: 196 YVHRDIKPDNVLLDVNGHIRLADFGSCLKMNDDGTVQSSVAVGTPDYISPEILQAMEDGM 255
            +HRDIK  N+LL+  GH +LADFG   ++ D    +++V +GTP +++PE++Q +    
Sbjct: 380 KIHRDIKAGNILLNNEGHAKLADFGVAGQLTDTMAKRNTV-IGTPYWMAPEVIQEI---- 544

Query: 256 GKYGPEC--DWWSLGVCMYEMLYGETPFYAESLV 287
              G +C  D WSLG+   EM  G+ P    S++
Sbjct: 545 ---GYDCVADIWSLGITALEMAEGKPPVMETSIL 637
>13212
          Length = 1067

 Score = 79.3 bits (194), Expect = 1e-14,   Method: Compositional matrix adjust.
 Identities = 43/135 (31%), Positives = 71/135 (52%), Gaps = 3/135 (2%)
 Frame = -1

Query: 149  LYLVMDYY---VGGDLLTLLSKFEDKLPEDMARFYIGEMVLAIDSIHQLHYVHRDIKPDN 205
            ++ ++D +     G L +++   E  + E    +   EM +A+D +H+ H +HRDIK  N
Sbjct: 1067 VWXIVDVFRVLWWGALDSIMVDLEKPMTEAQICYVCHEMCMALDFLHRHHVIHRDIKAGN 888

Query: 206  VLLDVNGHIRLADFGSCLKMNDDGTVQSSVAVGTPDYISPEILQAMEDGMGKYGPECDWW 265
            VLL ++G ++LADFG   K N     +    +GTP +++PE++         Y  + D W
Sbjct: 887  VLLTIDGEVKLADFGVSAK-NTQTQQKRDTFIGTPYWMAPEVVLCETLKDTPYDFKADIW 711

Query: 266  SLGVCMYEMLYGETP 280
            SLGV + E    E P
Sbjct: 710  SLGVTLIEFAQIEPP 666
>01392
          Length = 1806

 Score = 79.0 bits (193), Expect = 1e-14,   Method: Compositional matrix adjust.
 Identities = 55/177 (31%), Positives = 86/177 (48%), Gaps = 21/177 (11%)
 Frame = -1

Query: 172  LPEDMARFYIGEMVLAIDSIHQLHYVHRDIKPDNVL---LDVNGHIRLADF--GSCLKMN 226
            L E  A   +  +  A+D +H     HRD+KP+N+L   LD    +++ DF   S +  +
Sbjct: 1800 LCEREASLVVRHIARALDFLHSKGIAHRDLKPENILCEHLDDVVPVKICDFDLASGISCD 1621

Query: 227  DDGTVQSSV--AVGTPDYISPEILQAMEDGMGKYGPECDWWSLGVCMYEMLYGETPFY-- 282
             DGT    +   VG+ +Y++PE++ A       Y   CD WSLG+ +Y ML G  PFY  
Sbjct: 1620 GDGTKTPELLTPVGSAEYMAPEVVDAWVGDSFSYDKRCDLWSLGIILYIMLCGYPPFYGQ 1441

Query: 283  ---------AESLVETYGKIMN--HEERFQFPSH-VTDVSEEAKDLIQRLICSRERR 327
                      E+  +    + N   +  ++FPS   T +S  AKDLI+ L+    R+
Sbjct: 1440 CGEDCGWNRGEACHDCQDMLFNSIQDGHYKFPSQEWTSISSSAKDLIRHLLVREPRK 1270
>13592
          Length = 980

 Score = 78.2 bits (191), Expect = 3e-14,   Method: Compositional matrix adjust.
 Identities = 67/243 (27%), Positives = 116/243 (47%), Gaps = 7/243 (2%)
 Frame = +2

Query: 82  IGRGAFGEVAVVKMRNTERIYAMKILNKWEMLKRAETACFR---EERDVLVNGDCQWITA 138
           IG+G FG+V      NT  + AMK +     ++  ET   +   EE  +L     + +  
Sbjct: 8   IGQGRFGKVYTAVNNNTGELMAMKEI----AIQPGETRALKNVAEELKILEGIKHKNLVR 175

Query: 139 LHYAFQDENYLYLVMDYYVGGDLLTLLSKFEDKLPEDMARFYIGEMVLAIDSIHQLHYVH 198
            +        L + M+    G L +L+ +    LPE ++R +  +++  +  +H+   VH
Sbjct: 176 YYGIEVHREELLIFMELCSEGTLESLV-ELTGGLPEALSRRFTAQLLSGVAELHKHGIVH 352

Query: 199 RDIKPDNV-LLDVNGHIRLADFGSCLKMNDDGTVQSSVA--VGTPDYISPEIL-QAMEDG 254
           RDIK  N+ L+D +  ++L DFGS +K+    TV   +   VGT  Y++PE+  +   DG
Sbjct: 353 RDIKTANIFLVDGSNSLKLGDFGSAVKIQAHTTVPGELQGYVGTQAYMAPEVFTKTNSDG 532

Query: 255 MGKYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHEERFQFPSHVTDVSEEAK 314
            G+     D WS+G  + EM  G+ P+   +  ++  +IM      + P     +S+E  
Sbjct: 533 HGRL---ADIWSVGCVVVEMASGKRPW---AQFDSNFQIMFKVGMGEKPQAPESLSQEGH 694

Query: 315 DLI 317
           D I
Sbjct: 695 DFI 703
>01060
          Length = 1800

 Score = 73.9 bits (180), Expect = 5e-13,   Method: Compositional matrix adjust.
 Identities = 70/243 (28%), Positives = 106/243 (43%), Gaps = 12/243 (4%)
 Frame = +1

Query: 64  QLVKDMQLHREDFEIIKVIGRGAFGEVAVVKMRNTERIYAMKILNKWEMLKRAE------ 117
           +L+ D +    D    + IG G +G V   + R T R  AMK +     L+ +E      
Sbjct: 43  RLMMDFETALSDLTDFQKIGEGTYGVVYKCRHRATGRKLAMKKIR----LRGSEDGVPSS 210

Query: 118 ----TACFREERDVLVNGDCQWITALHYAFQDENYLYLVMDYYVGGDLLTLLSKFEDKLP 173
                A  RE R    N     I  L     ++  L+LV ++ +  DL   + KF + + 
Sbjct: 211 AIREIAMLRELRHT--N-----IVCLEDVIMEDERLFLVFEF-LSMDLKMYIDKFPEGVV 366

Query: 174 ED--MARFYIGEMVLAIDSIHQLHYVHRDIKPDNVLLDVNGHIRLADFGSCLKMNDDGTV 231
            D  + + Y+ ++V  I   HQ   VHRD+KP N+L++  G I++ADFG           
Sbjct: 367 LDRRLVKSYVFQIVTGIXFCHQRRIVHRDLKPQNLLINHTGAIKIADFGMARTFALPVRA 546

Query: 232 QSSVAVGTPDYISPEILQAMEDGMGKYGPECDWWSLGVCMYEMLYGETPFYAESLVETYG 291
            +   V T  Y +PEIL     G  KY    D WS+G    +ML     F  +S ++   
Sbjct: 547 YTHEVV-TLWYRAPEILM----GASKYSTPVDVWSIGTIFADMLIRTPIFKGDSEIDQLF 711

Query: 292 KIM 294
           KI 
Sbjct: 712 KIF 720
>14126
          Length = 1265

 Score = 70.9 bits (172), Expect = 4e-12,   Method: Compositional matrix adjust.
 Identities = 76/285 (26%), Positives = 122/285 (42%), Gaps = 31/285 (10%)
 Frame = +3

Query: 74  EDFEIIKVIGRGAFGEVAVVK-MRNTERIYAMKI--LNKWE----MLKRAETACFREERD 126
           + +E + VIG GA+G V   + +RN     AMK   LN  E    M+   E +  ++   
Sbjct: 189 QKYEEVAVIGNGAYGTVYKARDLRNQGEFVAMKRIRLNNTEEGMPMMAIREISMLKQLEQ 368

Query: 127 VLVNGDCQWITALHYAFQD-ENYLYLVMDYYVGGDLLTLLSKFED-KLPEDMARFYIGEM 184
                  + +   H    D E  L LV +Y +  DL T L+K     L  D  +  + ++
Sbjct: 369 YEHPNVVRLLDVSHNTITDREIRLNLVFEY-IEHDLATYLAKCPSPGLGPDRIKDLMLQL 545

Query: 185 VLAIDSIHQLHYVHRDIKPDNVLLDVNGHIRLADFGSCLKMNDDGTVQSSVAVGTPDYIS 244
           +  +D +H    VHRD+KP N+L+  +G ++LADFG   ++       ++V V T  Y S
Sbjct: 546 LNGVDFLHSNRIVHRDLKPQNLLISKDGRLKLADFGLA-RIYSFHMALTTVVV-TLWYRS 719

Query: 245 PEILQAMEDGMGKYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMN--------- 295
           PE+L   E     YG   D WS G    E+      F   S  +   KI           
Sbjct: 720 PEVLMQAE-----YGTSVDIWSCGCIFAELFTRRALFKGSSEFDQLKKIFEVIGLPPAGD 884

Query: 296 -------HEERFQ------FPSHVTDVSEEAKDLIQRLICSRERR 327
                  H   F+        + V ++  +AKDL+++++  +  R
Sbjct: 885 WPEGVSVHRNSFRPTPPVPLQTLVPEMDPQAKDLMEKMLVFKSGR 1019
>18663
          Length = 600

 Score = 68.6 bits (166), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 49/155 (31%), Positives = 75/155 (48%), Gaps = 15/155 (9%)
 Frame = +2

Query: 234 SVAVGTPDYISPEILQAMEDGMGKYGPECDWWSLGVCMYEMLYGETPF-------YAESL 286
           S   GTP+YI+PEIL+  ED    YG   DWW+LGV +YEML G +PF         +  
Sbjct: 2   STFCGTPNYIAPEILRG-ED----YGFSVDWWALGVLLYEMLAGRSPFDIAGASENPDQN 166

Query: 287 VETYGKIMNHEERFQFPSHVTDVSEEA------KDLIQRLICSRERRLGQNGIEDFKKHA 340
            E Y   +  E+  + P  ++  +         K+   RL C RE     +   D   H 
Sbjct: 167 TEDYLFQVILEKTIRIPRSLSVKAASVLKGFLNKNPADRLGCHRE-----SAFMDIVNHP 331

Query: 341 FFEGLNWENI--RNLEAPYIPDVSSPSDTSNFDVD 373
           FF+ ++WE +  + +  P+ P + S  D +NF ++
Sbjct: 332 FFKVIDWEMLERKQVSPPFKPRLDSDRDLANFPIE 436
>17722
          Length = 680

 Score = 67.4 bits (163), Expect = 4e-11,   Method: Compositional matrix adjust.
 Identities = 39/111 (35%), Positives = 59/111 (53%), Gaps = 5/111 (4%)
 Frame = -3

Query: 262 CDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHEERFQFPSHVTDVSEEAKDLIQRLI 321
            DWW  GV MYEM+ G  PFY       +  I+    +F       ++SEEAK L+  L+
Sbjct: 678 VDWWGTGVVMYEMMCGRLPFYNRDHDVLFELILLQNVKFP-----RNLSEEAKTLLSGLL 514

Query: 322 CSR-ERRLG--QNGIEDFKKHAFFEGLNWENI--RNLEAPYIPDVSSPSDT 367
               +RRLG  +  + + K H FF+ +NW+++  + +  P+ PDV S  DT
Sbjct: 513 AKNPKRRLGGSEADVTEIKTHPFFQCINWDDLAAKKITPPWKPDVKSSWDT 361
>01718
          Length = 959

 Score = 67.4 bits (163), Expect = 4e-11,   Method: Compositional matrix adjust.
 Identities = 60/213 (28%), Positives = 100/213 (46%), Gaps = 9/213 (4%)
 Frame = +3

Query: 71  LHREDFEIIKVIGRGAFGEVAVVKMRNTERIYAMKI----LNKWEMLKRAETACFREERD 126
           L R D  I + IG G F EV  V  R T ++ A+K+     N+  ML+  +     +  +
Sbjct: 138 LTRLDDFICEKIGAGFFSEVFKVTHRITGQVMALKMNTMTSNRHNMLREVQLLNRLQHAN 317

Query: 127 VL-VNGDCQWITALHYAFQDENYLYLVMDYYVGGDLLTLLSKFEDKLPEDMARFYIGEMV 185
           +L   G C     +H     E  L+ + +Y   G+L  LL K +++LP          + 
Sbjct: 318 ILRFMGVC-----VH-----EGQLHALTEYIPSGNLEQLLEKKDEELPWTQRIQLTLGLA 467

Query: 186 LAIDSIHQLHYVHRDIKPDNVLL---DVNG-HIRLADFGSCLKMNDDGTVQSSVAVGTPD 241
             +D +H   ++HRD+   N+L+   D +G H  +ADFG   K+ D    +    VG+P 
Sbjct: 468 RGLDYLHSTRFIHRDLTSKNILIRREDNHGYHAVIADFGLATKIPDPLDKEKLPTVGSPY 647

Query: 242 YISPEILQAMEDGMGKYGPECDWWSLGVCMYEM 274
           +++PE+L         Y    D +S+G+ M E+
Sbjct: 648 WMAPEVLNG-----HFYNERADLFSVGIIMCEI 731
>13066
          Length = 551

 Score = 67.0 bits (162), Expect = 7e-11,   Method: Compositional matrix adjust.
 Identities = 46/151 (30%), Positives = 75/151 (49%), Gaps = 3/151 (1%)
 Frame = +3

Query: 121 FREERDVLVNGDCQWITALHYAFQDENYLYLVMDYYVGGDLLTLLSKFEDKLPEDMARFY 180
           F  E D+L   D  +I  +H   Q     ++ M +   GDLLT + +    + E  A+ +
Sbjct: 117 FPRELDLLTKLDHPYIIQIHSILQRXPKNFIFMRFAERGDLLTYIQEV-GFVKEKQAKIW 293

Query: 181 IGEMVLAIDSIHQLHYVHRDIKPDNVLLDVNGHIRLADFG-SCLKMNDDG-TVQSSVAVG 238
             +M  A++ +H     HRD+K +N+LL  + +++LADFG +C  + + G    S    G
Sbjct: 294 FYQMTTALNYLHSYDVAHRDLKCENILLSSHFNVKLADFGFACACITESGEKYMSRTYCG 473

Query: 239 TPDYISPEILQAMEDGMGKYGPE-CDWWSLG 268
           +  Y +PEI+         Y P+  D WSLG
Sbjct: 474 SAAYAAPEIVYG-----APYAPKVADAWSLG 551
>26156
          Length = 479

 Score = 66.2 bits (160), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 36/106 (33%), Positives = 65/106 (61%), Gaps = 1/106 (0%)
 Frame = -1

Query: 75  DFEIIKVIGRGAFGEVAVVKMRNTERIYAMKILNKWEMLKRAETACFREERDVLVNG-DC 133
           DF +++VIGRG++ +V  V+ + T+RIYAMK++ K  +    +    + E+ V     + 
Sbjct: 386 DFLLLRVIGRGSYAKVLQVEHKRTKRIYAMKVIKKELVNDDEDIDWVQTEKHVFETATNY 207

Query: 134 QWITALHYAFQDENYLYLVMDYYVGGDLLTLLSKFEDKLPEDMARF 179
            ++  LH  FQ E+ L+ V+++  GGDL+  + + + +LPE+ ARF
Sbjct: 206 PFLVGLHSCFQSESRLFFVIEFVNGGDLMFHMQR-QRRLPEEHARF 72
>16708
          Length = 1397

 Score = 65.9 bits (159), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 46/156 (29%), Positives = 79/156 (50%), Gaps = 13/156 (8%)
 Frame = -1

Query: 78   IIKVIGRGAFGEVAVVKMRNTERIYAMKI-------LNKWEMLKRAETACFREERDVLVN 130
            I++V+G+G FG+V   ++ +T    A+K        L++ E L R E   +      L  
Sbjct: 1391 ILQVLGKGVFGKVYEARLLSTHEKAALKTSILCHHSLDEVEALGRIEGGFY------LAQ 1230

Query: 131  GDCQWITALHYAFQDENYLYLVMDYYVGGDLLTLLSKFEDK-LP-----EDMARFYIGEM 184
                W+T L   F   N   +++ +Y  G L  + + +++K +P       M     G+ 
Sbjct: 1229 MFGAWVTCL--PFPKMN---ILLHFYEMGPLCNVYAHYKNKEMPIRWSNPAMVCCIAGQX 1065

Query: 185  VLAIDSIHQLHYVHRDIKPDNVLLDVNGHIRLADFG 220
            V A++ IH+L  VH D+K DNVL+D +G+ +L D+G
Sbjct: 1064 VCALEHIHELGVVHMDVKADNVLVDAHGNCKLTDYG 957
>19094
          Length = 898

 Score = 65.5 bits (158), Expect = 2e-10,   Method: Composition-based stats.
 Identities = 34/89 (38%), Positives = 53/89 (59%), Gaps = 2/89 (2%)
 Frame = +1

Query: 191 IHQLHYVHRDIKPDNVLLDVNGHIRLADFGSCLKMNDDGTVQSSVAVGTPDYISPEILQA 250
           +H    +HRDIK  N+LL+  GH +LADFG   ++ D    +++V +GTP +++PE++Q 
Sbjct: 106 LHSRRKIHRDIKAGNILLNNEGHAKLADFGVAGQLTDTMAKRNTV-IGTPYWMAPEVIQE 282

Query: 251 MEDGMGKYGPEC--DWWSLGVCMYEMLYG 277
           +       G +C  D WSLG+   EM  G
Sbjct: 283 I-------GYDCVADIWSLGITALEMAEG 348
>17975
          Length = 449

 Score = 63.9 bits (154), Expect = 6e-10,   Method: Composition-based stats.
 Identities = 43/139 (30%), Positives = 77/139 (55%), Gaps = 6/139 (4%)
 Frame = +3

Query: 91  AVVKMRN---TERIYAMKILNKWEMLKRAETACFREERDVLVNGDCQWITALHYAFQDEN 147
           AVVK+     T    A+K+++K ++ + + +  F+E R + +      +  L+     + 
Sbjct: 9   AVVKLARHVFTGEKVAVKVIDKTKLDEVSRSHLFQEVRCMKLVQHPN-VVRLYEVIDTQT 185

Query: 148 YLYLVMDYYVGGDLLTLLSKFEDKLPEDMARFYIGEMVLAIDSIHQLHYVHRDIKPDNVL 207
            LYL+++   GGD+   + +    L E +A+ Y  ++V AI   H+LH VHRD+KP+NV+
Sbjct: 186 KLYLILELGDGGDMYDYIMRHSGGLEEKLAKRYFRQIVEAISYCHKLHVVHRDLKPENVV 365

Query: 208 -LDVNGHIRLADFG--SCL 223
             +  G ++L DFG  +CL
Sbjct: 366 FFEKPGLVKLTDFGFSTCL 422
>06405
          Length = 1965

 Score = 62.8 bits (151), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 52/225 (23%), Positives = 98/225 (43%), Gaps = 4/225 (1%)
 Frame = +1

Query: 70  QLHREDFEIIKVIGRGAFGEVAVVKMRNTERIYAMKILNKWEMLKRAETACFREERDVLV 129
           ++ R +  +   +G G +G+V     +   +I A+K L +  M        F EE  ++ 
Sbjct: 247 EIERTEIAMKHRLGGGQYGDVYEAMWKRYNKIVAVKTLKEDTMALND----FLEEAAIMK 414

Query: 130 NGDCQWITALHYAFQDENYLYLVMDYYVGGDLLTLL--SKFEDKLPEDMARFYIGEMVLA 187
                 +  L      E   Y+V ++   G+LL  L  S  E+  P  +  +   ++   
Sbjct: 415 EMKHPNLVQLLGVCTREPPFYIVTEFMPHGNLLDYLRSSTREENGPTALM-YMATQIASG 591

Query: 188 IDSIHQLHYVHRDIKPDNVLLDVNGHIRLADFGSCLKMNDDGTVQSSVAVGTP-DYISPE 246
           +  +   +++HRD+   N L+  +  +++ADFG    M DD T  + +    P  + +PE
Sbjct: 592 MAYLETKNFIHRDLAARNCLVADSNMVKVADFGLARLMKDD-TYTAHIGAKFPIKWTAPE 768

Query: 247 ILQAMEDGMGKYGPECDWWSLGVCMYEM-LYGETPFYAESLVETY 290
            L        ++    D W+ GV ++E+  YG +P+    L E Y
Sbjct: 769 GL-----AFNRFSTRSDIWAFGVLLWELATYGMSPYPGVELTEVY 888
>25445
          Length = 460

 Score = 62.0 bits (149), Expect = 2e-09,   Method: Composition-based stats.
 Identities = 25/59 (42%), Positives = 34/59 (57%), Gaps = 3/59 (5%)
 Frame = -1

Query: 1021 GPKPKA---HQFSIKSFPSPTQCSHCTSLMVGLIRQGYACEVCAFSCHVSCKDSAPQVC 1076
            GP   A   H+F   ++ SPT C HC SL+ GLI QG  C+ C  +CH  C+   P++C
Sbjct: 424  GPDSDATNLHKFKAHTYGSPTFCDHCGSLLYGLIHQGLKCDSCDMNCHKRCEKHVPRLC 248
>26711
          Length = 405

 Score = 62.0 bits (149), Expect = 2e-09,   Method: Composition-based stats.
 Identities = 41/132 (31%), Positives = 65/132 (49%), Gaps = 2/132 (1%)
 Frame = -2

Query: 188 IDSIHQLHYVHRDIKPDNVLL--DVNGHIRLADFGSCLKMNDDGTVQSSVAVGTPDYISP 245
           +  +H    VH D+KP N+LL  D    ++L DFG   K+      ++ +  GTP + SP
Sbjct: 377 LQHVHAQGVVHMDLKPSNLLLSGDKLDSVQLIDFGLARKLYPPQ--ETFLNHGTPGFTSP 204

Query: 246 EILQAMEDGMGKYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHEERFQFPSH 305
           E L      +       D W +GV  Y +L G++PF A+S  E+  K    +  F     
Sbjct: 203 EALD-----VKPISTASDVWGVGVLAYILLSGQSPFQADSATESLKKTQTCDWSFDVCPS 39

Query: 306 VTDVSEEAKDLI 317
            +++S++AKD I
Sbjct: 38  FSNMSQDAKDFI 3
>33586
          Length = 551

 Score = 52.4 bits (124), Expect(2) = 6e-09,   Method: Composition-based stats.
 Identities = 27/57 (47%), Positives = 36/57 (63%), Gaps = 3/57 (5%)
 Frame = +2

Query: 131 GDCQ---WITALHYAFQDENYLYLVMDYYVGGDLLTLLSKFEDKLPEDMARFYIGEM 184
           G CQ   +I  LHYAFQ E  LYL++++  GGDL T LSK E    E+  +FY+ E+
Sbjct: 383 GGCQPPLFIVHLHYAFQTEGKLYLILEFLRGGDLFTRLSK-EVMFTEEDVKFYLAEL 550

 Score = 27.7 bits (60), Expect(2) = 6e-09,   Method: Compositional matrix adjust.
 Identities = 9/15 (60%), Positives = 14/15 (93%)
 Frame = +1

Query: 76  FEIIKVIGRGAFGEV 90
           FE++KV+G+G+FG V
Sbjct: 220 FELLKVLGQGSFGRV 264
>21079
          Length = 878

 Score = 58.5 bits (140), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 40/141 (28%), Positives = 70/141 (49%), Gaps = 2/141 (1%)
 Frame = +1

Query: 142 AFQDENYLYLVMDYYVGGDLLTLLSKFEDKLPEDMARFYIGEMVLAIDSIHQLHYVHRDI 201
           AF+    + LVM++   G+L   + + +  L E     ++ ++   +  +H    +H D+
Sbjct: 28  AFEAPRTMVLVMEFVGAGELFERVIRDDFVLTERDCVHFVRQICSGVGYMHTQSILHLDL 207

Query: 202 KPDNVLL--DVNGHIRLADFGSCLKMNDDGTVQSSVAVGTPDYISPEILQAMEDGMGKYG 259
           KP+NVL   D +  I++ DFG         ++Q  V  GTP++I+PE++   E       
Sbjct: 208 KPENVLCVSDNSNQIKIIDFGLARFYKPGDSLQ--VLFGTPEFIAPEVVNYDEINFTT-- 375

Query: 260 PECDWWSLGVCMYEMLYGETP 280
              D WS+GV  Y +L G +P
Sbjct: 376 ---DMWSIGVICYILLSGLSP 429
>04591
          Length = 1117

 Score = 57.8 bits (138), Expect = 4e-08,   Method: Compositional matrix adjust.
 Identities = 41/126 (32%), Positives = 60/126 (47%)
 Frame = -2

Query: 149 LYLVMDYYVGGDLLTLLSKFEDKLPEDMARFYIGEMVLAIDSIHQLHYVHRDIKPDNVLL 208
            YL+ +Y    DL  LL+    K      +  + +++  +  IH    +HRDIK  N+LL
Sbjct: 972 FYLIFEY-CDYDLAGLLNNLRVKFSLADKKNLMSQLLNGLFYIHTKQILHRDIKAANILL 796

Query: 209 DVNGHIRLADFGSCLKMNDDGTVQSSVAVGTPDYISPEILQAMEDGMGKYGPECDWWSLG 268
             +G ++LADFG          + + V   T  Y  PE+L     G  +YGPE D W +G
Sbjct: 795 TRDGVLKLADFGLSRPWVKSKRLTNRVV--TLWYRPPELLL----GEREYGPEIDMWGVG 634

Query: 269 VCMYEM 274
             M EM
Sbjct: 633 CIMAEM 616
>35187
          Length = 593

 Score = 57.8 bits (138), Expect = 4e-08,   Method: Composition-based stats.
 Identities = 27/71 (38%), Positives = 33/71 (46%)
 Frame = -3

Query: 1006 PSPVPLPSTQALAMAGPKPKAHQFSIKSFPSPTQCSHCTSLMVGLIRQGYACEVCAFSCH 1065
            PS  P+P              H F+ K+F  PT C HCT ++ GLI  GY CEVC F  H
Sbjct: 354  PSDSPVPPDHG--------HGHFFTKKTFHKPTYCHHCTDILWGLIGVGYVCEVCNFVVH 199

Query: 1066 VSCKDSAPQVC 1076
              C  +    C
Sbjct: 198  DRCMKTVVSPC 166
>19761
          Length = 473

 Score = 57.0 bits (136), Expect = 7e-08,   Method: Compositional matrix adjust.
 Identities = 45/156 (28%), Positives = 73/156 (46%), Gaps = 2/156 (1%)
 Frame = -3

Query: 168 FEDKLPEDMARFYIGEMVLAIDSIHQLHYV--HRDIKPDNVLLDVNGHIRLADFGSCLKM 225
           F   LPE +   ++ +   A++ +H    V  HRD+KP N+ +   G +RL D G   K+
Sbjct: 444 FTAGLPERLIVCWLMQTASALNYMHTHTPVILHRDLKPQNIYVTEKGDVRLGDLGLARKL 265

Query: 226 NDDGTVQSSVAVGTPDYISPEILQAMEDGMGKYGPECDWWSLGVCMYEMLYGETPFYAES 285
                  +S  VGT  Y+SPEIL         Y  + D WSLG C++  + G+       
Sbjct: 264 TGPADFATS-QVGTIMYLSPEILSQQP-----YNSKSDIWSLG-CVFYDITGKKGSDEMG 106

Query: 286 LVETYGKIMNHEERFQFPSHVTDVSEEAKDLIQRLI 321
           ++    ++M    +   P H    S+E +D I R++
Sbjct: 105 VMFLLVQVMG-GRKLPLPDH---YSQEFRDTISRML 10
>00715
          Length = 1788

 Score = 56.6 bits (135), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 42/166 (25%), Positives = 78/166 (46%), Gaps = 21/166 (12%)
 Frame = +1

Query: 137 TALHYAFQDENYLYLVMDYYVGGDLLTLLSKFEDKLPEDMARFYIGEMVLAIDSIHQLHY 196
           T+LH   + E+  +L M+Y    +L T+L+  +  +   M      +M   +  +H ++ 
Sbjct: 133 TSLH---RFEDGAWLAMEYVGPLNLQTILNDHQQDIDSSMRLSLALQMARGLHYLHSINI 303

Query: 197 VHRDIKPDNVLLDVNGHIRLADFGSCLKMN----DDGTVQSSVA---------------- 236
           VH D+KP N LL  +  +R+ADFG C ++     D G  +  +A                
Sbjct: 304 VHLDLKPANCLLTRDLKLRIADFGCCHQLTPTGLDMGEREGGMAGNELELTPVQGAWKNE 483

Query: 237 -VGTPDYISPEILQAMEDGMGKYGPECDWWSLGVCMYEMLYGETPF 281
             GT  Y +PE+L+ ++  +       D +SLG+ +++M   + P+
Sbjct: 484 LAGTLAYRAPELLKGLQPSV-----RSDVYSLGITLWQMCTRQGPY 606
>11185
          Length = 473

 Score = 56.2 bits (134), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 33/115 (28%), Positives = 51/115 (44%), Gaps = 21/115 (18%)
 Frame = +1

Query: 184 MVLAIDSIHQLHYVHRDIKPDNVLLDVNGHIRLADFG--------------SCLKMNDDG 229
           +V  +  IH L  +  D++P  VLLD +G ++ ADFG                 +  D  
Sbjct: 28  LVTGLHYIHSLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEAGDQW 207

Query: 230 TVQSSVAV-------GTPDYISPEILQAMEDGMGKYGPECDWWSLGVCMYEMLYG 277
            +QS+  +       G+P Y++PE+ Q  E  +       D W+LG   YEM  G
Sbjct: 208 NIQSAEEMMKQVPTSGSPTYMAPEVFQGAEPSI-----MSDLWALGCVFYEMFSG 357
>19361
          Length = 685

 Score = 55.5 bits (132), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 37/145 (25%), Positives = 58/145 (40%)
 Frame = -1

Query: 947  FQDSIFEYFNTAPLAHDLTFRTSSASDQETQASKMDLSPSVSVATSTEQQEDMARPQQRP 1006
            +++S +  +N   L HD T R         Q     +SP ++  +S       + P++  
Sbjct: 523  YEESPYMAYNQCRLRHDKTLRVRPTGTYRRQG----VSPDITDDSSDNVDTVNSTPEEDE 356

Query: 1007 SPVPLPSTQALAMAGPKPKAHQFSIKSFPSPTQCSHCTSLMVGLIRQGYACEVCAFSCHV 1066
                +  TQ         K H F +++F     C  C + M GLI QG  C+ C    H 
Sbjct: 355  PEQSIDWTQY-------EKPHVFKVQNFNGLNWCELCANFMWGLIAQGVKCQDCGVQTHK 197

Query: 1067 SCKDSAPQVCPIPPEQSKRPLGVDV 1091
             C +  P  C    +  KR  GVD+
Sbjct: 196  KCSERMPNECMPNMKYVKRLYGVDL 122
>25019
          Length = 730

 Score = 55.5 bits (132), Expect = 2e-07,   Method: Composition-based stats.
 Identities = 31/65 (47%), Positives = 39/65 (60%)
 Frame = +3

Query: 204 DNVLLDVNGHIRLADFGSCLKMNDDGTVQSSVAVGTPDYISPEILQAMEDGMGKYGPECD 263
           +NVLLD +GH++L DFG C K    GT  +    GT +Y++PEIL     G GK     D
Sbjct: 261 ENVLLDKDGHVKLTDFGLC-KEAITGTRVTHTFCGTIEYMAPEIL--TRTGHGK---AVD 422

Query: 264 WWSLG 268
           WWSLG
Sbjct: 423 WWSLG 437
>01966
          Length = 1735

 Score = 55.1 bits (131), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 29/87 (33%), Positives = 50/87 (57%), Gaps = 2/87 (2%)
 Frame = -1

Query: 136  ITALHYAFQDENYLYLVMDYYVGGDLLTLLSKFEDKLPED--MARFYIGEMVLAIDSIHQ 193
            I  L     ++  L+LV ++ +  DL   + KF + +  D  + + Y+ ++V  I+  HQ
Sbjct: 1528 IVCLEDVIMEDERLFLVFEF-LSMDLKMYIDKFPEGVVLDRRLVKSYVFQIVTGINFCHQ 1352

Query: 194  LHYVHRDIKPDNVLLDVNGHIRLADFG 220
               VHRD+KP N+L++  G I++ADFG
Sbjct: 1351 RRIVHRDLKPQNLLINHTGAIKIADFG 1271
>00392
          Length = 668

 Score = 54.3 bits (129), Expect = 4e-07,   Method: Compositional matrix adjust.
 Identities = 57/230 (24%), Positives = 100/230 (43%), Gaps = 15/230 (6%)
 Frame = +3

Query: 109 KWEMLKRAETACFREERDVLVNGDCQWITALHYAFQDENY-----LYLVMDYYVGGDLLT 163
           KW    +AE   F+EE ++L       I      +++ N+     + LV +    G L T
Sbjct: 45  KW---NKAERQRFKEEAEMLKELQHPNIVRFFDYWEEHNHRNRKVIILVTELMTSGTLKT 215

Query: 164 LLSKFED---KLPEDMARFYIGEMVLAIDSIHQLH-----YVHRDIKPDNVLL-DVNGHI 214
            L +F+    K+ ++  R         +  ++ LH      +HRD+K DN+ +    G +
Sbjct: 216 YLKRFKKPNVKILKNWCR-------QVLKGLYFLHTRTPPVIHRDLKCDNIFITGPTGSV 374

Query: 215 RLADFGSCLKMNDDGTVQSSVAVGTPDYISPEILQAMEDGMGKYGPECDWWSLGVCMYEM 274
           ++ D G  L    + +   SV +GTP++++PE+ +        Y    D ++ G+CM EM
Sbjct: 375 KIGDLG--LATLKNQSFAKSV-IGTPEFMAPEMYEE------HYDEAVDVYAFGMCMLEM 527

Query: 275 LYGETPFYAESLVETYGKIMNHEERFQFPSHVTDVS-EEAKDLIQRLICS 323
              E P+   S      +I         P  +  V+  E +D+I   ICS
Sbjct: 528 ASSEYPY---SECSNAAQIYKRVTSGVLPEALDKVAITEIRDIIHHCICS 668
>21433
          Length = 590

 Score = 54.3 bits (129), Expect = 5e-07,   Method: Composition-based stats.
 Identities = 38/103 (36%), Positives = 57/103 (55%), Gaps = 1/103 (0%)
 Frame = +2

Query: 180 YIGEMVLAIDSIHQLHYVHRDIKPDNVLLDVNGHIRLADFGSCLKMNDDGTVQSSVAVGT 239
           YI ++  A++  H    +HRDIKP+N+LL + G +++ADFG  +      + + +   GT
Sbjct: 182 YIYQLSSALEYCHYRKVIHRDIKPENLLLGLKGDLKIADFGWSVHAP---SSRRTTMCGT 352

Query: 240 PDYISPEILQAMEDGMGKYGPE-CDWWSLGVCMYEMLYGETPF 281
            DY+ PE+++      GK   E  D WSLGV  YE L G  P 
Sbjct: 353 LDYLPPEMVE------GKTHDENVDLWSLGVLCYEFLVGTPPL 463
>01756
          Length = 1858

 Score = 53.5 bits (127), Expect = 7e-07,   Method: Compositional matrix adjust.
 Identities = 61/215 (28%), Positives = 95/215 (44%), Gaps = 16/215 (7%)
 Frame = -3

Query: 76   FEIIKVIGRGAFGEVAVVKMRNTERIYAMKILNKWEMLKRAETACFREERDV----LVNG 131
            +E +  IG+G FGEV   + + T+++ AMK   K  M    E       R++    L+N 
Sbjct: 1736 YEKLAKIGQGTFGEVFKARCKKTKQVVAMK---KVLMDNEKEGFPITALREIKILQLLNH 1566

Query: 132  D--------CQWITALHYAFQDENYLYLVMDYYVGGDLLTLLSKFED--KLPEDMARFYI 181
            +        C   T    A + ++  YLV ++    DL  LLS       LPE   +  +
Sbjct: 1565 ENVVDLIEICS--TKATSANRYKSMFYLVFEF-CEHDLAGLLSNMSVVFNLPE--IKEVM 1401

Query: 182  GEMVLAIDSIHQLHYVHRDIKPDNVLLDVNGHIRLADFG--SCLKMNDDGTVQSSVAVGT 239
             +++  +  IH+   +HRD+K  N+L+   G ++LADFG      +N     + +  V T
Sbjct: 1400 KQLMNGLYYIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRVVT 1221

Query: 240  PDYISPEILQAMEDGMGKYGPECDWWSLGVCMYEM 274
              Y  PE+L     G   Y    D W  G  M EM
Sbjct: 1220 LWYRPPELLL----GDRNYSTAIDQWGAGCIMAEM 1128
>03508
          Length = 1463

 Score = 52.8 bits (125), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 34/104 (32%), Positives = 55/104 (52%), Gaps = 1/104 (0%)
 Frame = +1

Query: 178 RFYIGEMVLAIDSIHQLHYVHRDIKPDNVLLDV-NGHIRLADFGSCLKMNDDGTVQSSVA 236
           RFY+ E++ A+D  H +  +HRD+KP NV++D  N  +RL D+G  L       ++ +V 
Sbjct: 880 RFYLYELMKALDFCHSMGIMHRDVKPHNVMIDHENKKLRLIDWG--LAEFYHPGMEYNVR 1053

Query: 237 VGTPDYISPEILQAMEDGMGKYGPECDWWSLGVCMYEMLYGETP 280
           V +  +  PE+L   +     Y    D WSLG     M++ + P
Sbjct: 1054VASRYFKGPELLLDYQ----MYDYSLDMWSLGCMFASMIFRKEP 1173
>29581
          Length = 1278

 Score = 51.2 bits (121), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 39/135 (28%), Positives = 64/135 (47%), Gaps = 2/135 (1%)
 Frame = -2

Query: 149  LYLVMDYYVGGDLLTLLSKFEDKLPEDMARFYIGEMVLAIDSIHQLHYVHRDIKPDNVLL 208
            L+LVM+Y    DL +LL        E   +  + +++  +  +H+   +HRD+K  N+L+
Sbjct: 1124 LFLVMEY-CEQDLASLLDNMPAPFSESQVKCIVLQLLKGLRYLHEAFIIHRDLKVSNLLM 948

Query: 209  DVNGHIRLADFGSCLKMNDDGTVQSSVA--VGTPDYISPEILQAMEDGMGKYGPECDWWS 266
               G +++ADFG      + G  Q  +   V T  Y +PE+L     G   +    D WS
Sbjct: 947  TDKGCVKIADFGLA---RNYGKPQKPMTPKVVTLWYRAPELL----FGSKTHSTAIDMWS 789

Query: 267  LGVCMYEMLYGETPF 281
             G  + E+L G  P 
Sbjct: 788  AGCILGELL-GHKPL 747
>17591
          Length = 474

 Score = 37.7 bits (86), Expect(2) = 4e-06,   Method: Compositional matrix adjust.
 Identities = 19/51 (37%), Positives = 32/51 (62%), Gaps = 3/51 (5%)
 Frame = +3

Query: 324 RERRLG-QNGIEDFKKHAFFEGLNWENIRN--LEAPYIPDVSSPSDTSNFD 371
           +E RLG +   E+ ++ AFF  +NW+++ N  ++ PY P+VS   D  +FD
Sbjct: 147 KEERLGAKRDFEEIQEKAFFADINWDDLYNKKVQPPYNPNVSGQLDLRHFD 299

 Score = 32.3 bits (72), Expect(2) = 4e-06,   Method: Composition-based stats.
 Identities = 18/61 (29%), Positives = 33/61 (54%)
 Frame = +2

Query: 272 YEMLYGETPFYAESLVETYGKIMNHEERFQFPSHVTDVSEEAKDLIQRLICSRERRLGQN 331
           +EMLYG  PFY+    E Y  I+    R +     T+VS   +++++ L+  ++ + G+ 
Sbjct: 2   FEMLYGLPPFYSRDTSEMYENILYKPLRLR-----TNVSAAGRNILEELL--KKEKGGET 160

Query: 332 G 332
           G
Sbjct: 161 G 163
>27546
          Length = 426

 Score = 48.9 bits (115), Expect = 2e-05,   Method: Composition-based stats.
 Identities = 28/100 (28%), Positives = 50/100 (50%)
 Frame = -1

Query: 121 FREERDVLVNGDCQWITALHYAFQDENYLYLVMDYYVGGDLLTLLSKFEDKLPEDMARFY 180
           F  E ++L   D   I  +H   Q    +++ M Y   GD+L+ + K    + E   + +
Sbjct: 339 FPRELEILTRLDHPNIIQIHSILQRGPKIFIFMRYAEKGDMLSHIKK-TGPIDEAQTKVW 163

Query: 181 IGEMVLAIDSIHQLHYVHRDIKPDNVLLDVNGHIRLADFG 220
             +M  A+  +H     HRD+K +N+LL    ++++ADFG
Sbjct: 162 FFQMAKALQYLHSHDIAHRDLKCENILLSKRLNVKIADFG 43
>20152
          Length = 445

 Score = 48.1 bits (113), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 29/77 (37%), Positives = 42/77 (54%)
 Frame = +1

Query: 245 PEILQAMEDGMGKYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHEERFQFPS 304
           PEIL     G     P  D WSLGV +Y ++ GE PF   +  ET   IM+   R+Q P 
Sbjct: 1   PEILL----GDSYDAPAVDVWSLGVILYMLVVGEAPFQEANDSETLTMIMDC--RYQIPP 162

Query: 305 HVTDVSEEAKDLIQRLI 321
           H   +S + +DLI++++
Sbjct: 163 H---ISHKCQDLIEKML 204
>17300
          Length = 480

 Score = 47.4 bits (111), Expect = 5e-05,   Method: Composition-based stats.
 Identities = 40/146 (27%), Positives = 63/146 (43%), Gaps = 4/146 (2%)
 Frame = +1

Query: 196 YVHRDIKPDNVLLDVNGHIRLADFGSCLKMNDDGTVQSSVAVGTP---DYISPEILQAME 252
           YVHRD+   N+L++     ++ADFG   ++  D T  +    G      + +PE +    
Sbjct: 37  YVHRDLAARNILVNEILVCKVADFGLSREIESDTTEGAYTTKGGKIPVRWTAPEAI---- 204

Query: 253 DGMGKYGPECDWWSLGVCMYE-MLYGETPFYAESLVETYGKIMNHEERFQFPSHVTDVSE 311
               K+    D WS GV M+E M YGE P++  S  +    +   E+ ++ P H    S 
Sbjct: 205 -AYRKFTSASDVWSFGVVMWEVMSYGERPYWNWSNQDVIKAV---EKGYRLPLHGLSGSP 372

Query: 312 EAKDLIQRLICSRERRLGQNGIEDFK 337
            + D          RRL +  I   K
Sbjct: 373 SSTD---------ARRLAEGEISQTK 423
>12672
          Length = 773

 Score = 45.8 bits (107), Expect = 1e-04,   Method: Composition-based stats.
 Identities = 36/124 (29%), Positives = 61/124 (49%), Gaps = 3/124 (2%)
 Frame = +3

Query: 196 YVHRDIKPDNVLLDVNGHIRLADFGSCLKM--NDDGTVQ-SSVAVGTPDYISPEILQAME 252
           +VHRDIK  N+LLD     ++ DF + +     +  TVQ +SV +GT  Y++PE +    
Sbjct: 54  HVHRDIKTANILLDSEYTAKVGDFATVVSAPSGEGKTVQNASVVIGTAAYLAPEAIHF-- 227

Query: 253 DGMGKYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHEERFQFPSHVTDVSEE 312
                   + D +S GV + E++ G        + + Y +    EER    SH+ +  EE
Sbjct: 228 ----DVSTKLDSYSFGVVLLEVITG-------LVAQDYSR----EER-TLSSHIMENVEE 359

Query: 313 AKDL 316
            +++
Sbjct: 360 PEEI 371
>14116
          Length = 1017

 Score = 44.7 bits (104), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 34/126 (26%), Positives = 62/126 (49%), Gaps = 1/126 (0%)
 Frame = -1

Query: 151 LVMDYYVGGDLLTLLSKFEDKLPEDMARFYIGEMVLAIDSIHQLHYVHRDIKPDNVLLDV 210
           +V+ +   GDLLT +   + +        Y  ++   +D +  L +VHRD+   N +LD 
Sbjct: 393 VVLPFMKHGDLLTYIRDDQHQPTIKDLIMYGVDIARGMDYLAGLKFVHRDLAARNCMLDE 214

Query: 211 NGHIRLADFGSCLKMNDDGTVQS-SVAVGTPDYISPEILQAMEDGMGKYGPECDWWSLGV 269
           + H+++ADFG    + +     S +     P  +    L+++E   G Y  + D WS GV
Sbjct: 213 DFHVKVADFGLARDIYEKEYYSSENKKAKLP--VKWMALESLEK--GNYDSKTDVWSYGV 46

Query: 270 CMYEML 275
            ++E+L
Sbjct: 45  VLWELL 28
>28638
          Length = 1458

 Score = 44.3 bits (103), Expect = 5e-04,   Method: Composition-based stats.
 Identities = 30/93 (32%), Positives = 45/93 (48%), Gaps = 4/93 (4%)
 Frame = -1

Query: 193 QLHYVHRDIKPDNVLL--DVNGHIRLADFGSCLKMNDD--GTVQSSVAVGTPDYISPEIL 248
           +++ +H D+KP+N+LL       I++ DFGS  ++       +QS        Y SPE+L
Sbjct: 777 EMNIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRF------YRSPEVL 616

Query: 249 QAMEDGMGKYGPECDWWSLGVCMYEMLYGETPF 281
             +      Y    D WSLG  + EM  GE P 
Sbjct: 615 LGV-----PYDLAIDMWSLGCILVEMHTGEPPL 532
>37063
          Length = 455

 Score = 43.1 bits (100), Expect = 0.001,   Method: Composition-based stats.
 Identities = 25/78 (32%), Positives = 41/78 (52%), Gaps = 7/78 (8%)
 Frame = -2

Query: 201 IKPDNVL---LDVNGHIRLADFGSCLKMNDDG----TVQSSVAVGTPDYISPEILQAMED 253
           +KP+N+L   LD    +++ DF     +N DG    T +    VG+ +Y++PE++ A   
Sbjct: 454 LKPENILCEHLDEVVPLKICDFDLASGINCDGDGTKTPELLTPVGSAEYMAPEVVDAWVG 275

Query: 254 GMGKYGPECDWWSLGVCM 271
               Y   CD WSLG+ +
Sbjct: 274 ESFSYDKRCDMWSLGIIL 221
>11353
          Length = 454

 Score = 42.7 bits (99), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 16/50 (32%), Positives = 26/50 (52%)
 Frame = +1

Query: 1027 HQFSIKSFPSPTQCSHCTSLMVGLIRQGYACEVCAFSCHVSCKDSAPQVC 1076
            H+F   ++ +PT C  C  L+ G  + G  C  C ++CH  C+   P+ C
Sbjct: 142  HRFEKYTYTTPTYCDFCQQLLWGFSKTGTHCVDCGYNCHDKCQPLVPKTC 291
>21808
          Length = 1011

 Score = 42.4 bits (98), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 24/89 (26%), Positives = 45/89 (50%), Gaps = 2/89 (2%)
 Frame = +1

Query: 195 HYVHRDIKPDNVLLDVNGHIRLADFGSCLKMNDDGTVQSSVAVGTP-DYISPEILQAMED 253
           +Y+HRD+   N+L+  N  +++ADFG    + +D   ++ V    P  + +PE       
Sbjct: 295 NYIHRDLAARNILVSDNNTVKIADFGLARVIKED-EYEARVGARFPIKWTAPE-----AA 456

Query: 254 GMGKYGPECDWWSLGVCMYEML-YGETPF 281
              ++  + D WS G+ + E + YG  P+
Sbjct: 457 NYNRFTIKSDVWSFGILLTETVTYGRVPY 543
>29590
          Length = 320

 Score = 42.0 bits (97), Expect = 0.002,   Method: Composition-based stats.
 Identities = 21/48 (43%), Positives = 27/48 (56%), Gaps = 3/48 (6%)
 Frame = +3

Query: 237 VGTPDYISPEILQAMEDGMGKYGP---ECDWWSLGVCMYEMLYGETPF 281
           +GTPDY++PE+L         Y P   + D WSLGV  Y ML   +PF
Sbjct: 57  IGTPDYVAPEVLD--------YEPLSIQTDMWSLGVLSYVMLTACSPF 176
>04852
          Length = 1462

 Score = 42.0 bits (97), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 31/108 (28%), Positives = 51/108 (47%), Gaps = 1/108 (0%)
 Frame = +1

Query: 197 VHRDIKPDNVLLDVNGHIRLADFGSCLKMNDDGTVQSSVAVGTPDYISPEILQAMEDGMG 256
           +HRD+   NVL+     +++ADFG  L    D   + S       +++PE L  M     
Sbjct: 391 IHRDLAARNVLVTEEHVLKIADFG--LSRTGDYYKKRSGGRLPVKWMAPEALFDM----- 549

Query: 257 KYGPECDWWSLGVCMYEML-YGETPFYAESLVETYGKIMNHEERFQFP 303
           +Y  + D WS GV ++E+   G  P+ +    E Y K+++   R   P
Sbjct: 550 RYTTKSDVWSFGVVLWEIFSLGGMPYASIPNEELYSKLLDDAYRMPRP 693
>22804
          Length = 967

 Score = 41.6 bits (96), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 16/50 (32%), Positives = 26/50 (52%)
 Frame = -3

Query: 1027 HQFSIKSFPSPTQCSHCTSLMVGLIRQGYACEVCAFSCHVSCKDSAPQVC 1076
            H+F   ++ +PT C  C  L+ G  + G  C  C ++CH  C+   P+ C
Sbjct: 830  HRFEKYTYTTPTYCDFCQQLLWGFSKTGTHCVDCGYNCHDKCQPLVPKTC 681
>18996
          Length = 491

 Score = 41.6 bits (96), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 27/86 (31%), Positives = 41/86 (47%), Gaps = 2/86 (2%)
 Frame = +2

Query: 197 VHRDIKPDNVLLDVNGHIRLADFGSCLKMNDDGTVQSSVAVGTP-DYISPEILQAMEDGM 255
           +HRD+   N+L+D    ++++DFG     N DG          P  + SPE ++      
Sbjct: 2   IHRDLAARNILVD-RSCVKISDFGLAQFANADGYYYGISQRDIPIKWYSPEAIETC---- 166

Query: 256 GKYGPECDWWSLGVCMYEMLY-GETP 280
            K+    D WS GV ++EM   GE P
Sbjct: 167 -KFSSYSDVWSYGVTLFEMFSRGEIP 241
>01431
          Length = 1309

 Score = 41.6 bits (96), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 61/274 (22%), Positives = 112/274 (40%), Gaps = 22/274 (8%)
 Frame = +2

Query: 1244 VLAAAIVDGDRIAVGLEEGLYVIELT-RDVIVRAADCKKVYQIELAPKEKIAILLCGRNH 1302
            +L AA+  G  + +G E GL +++ + +  + +    ++  Q+E+   + I + + G+ +
Sbjct: 35   ILCAALW-GVNLLIGTENGLMLLDRSGQGKVYQLISRRRFQQMEVLEGQNILVTISGKKN 211

Query: 1303 HVHLYPWSSF-----------DGAEASNFDIKLPETKGCQLIATGTLRKSSSTCLFVAVK 1351
             V +Y  S             D  E  N  I + + +G   +    ++      L +A+K
Sbjct: 212  RVRVYYLSWLKSKILRTDGLSDQVERRNGWINVGDLQGA--VHFKIVKYERIKFLVIALK 385

Query: 1352 RLILCYEIQRTKPFHRKFSELVAPGHVQWMAVFKD-------RLCVGYPSGFSLLSIQGD 1404
              I  Y     KP+H KF      G ++   +  D       RL V Y S     ++   
Sbjct: 386  DSIEIYA-WAPKPYH-KFMAFKNFGELEHRPLLVDLTIEDQSRLKVIYGSAEGFHAVD-- 553

Query: 1405 GPPLDLVNPTDPSLAFLSQQSFDALCAVEL---KSEEYLLCFSHMGLYVDPQGRRSRMQE 1461
               LD     D  L   +Q +    C V L      + LLC+ + G+YV+  GR S+   
Sbjct: 554  ---LDSAEVYDIYLPKHTQGAIIPHCIVALPNSNGMQLLLCYDNEGVYVNTAGRVSKNIV 724

Query: 1462 LMWPAAPVACSCSPTHVTVYSEYGVDVFDVRTME 1495
            L W   P + +   T   +   +G    ++R++E
Sbjct: 725  LQWGEMPTSVAYIGTGQIM--GWGNKAIEIRSVE 820
>27274
          Length = 396

 Score = 40.8 bits (94), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 22/76 (28%), Positives = 37/76 (48%), Gaps = 11/76 (14%)
 Frame = -1

Query: 257 KYGPECDWWSLGVCMYEMLYGETPF--------YAESLVETYGKIMNHEERFQFPSHVTD 308
           ++GP  D WSLG+ ++E+L G  PF         A +++  Y +I+    R      V D
Sbjct: 357 QHGPTVDMWSLGILLHELLSGHVPFEPERGSRQMARNMMAVYAQIIRGSSR-----DVCD 193

Query: 309 ---VSEEAKDLIQRLI 321
              +S    D ++RL+
Sbjct: 192 GLALSTHGADFLRRLV 145
>04138
          Length = 800

 Score = 40.8 bits (94), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 29/86 (33%), Positives = 40/86 (46%), Gaps = 2/86 (2%)
 Frame = +1

Query: 191 IHQLHYVHRDIKPDNVLLDVNGHIRLADFG--SCLKMNDDGTVQSSVAVGTPDYISPEIL 248
           IH+   +HRD+K  N+L+   G ++LADFG      +N     + +  V T  Y  PE+L
Sbjct: 61  IHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRVVTLWYRPPELL 240

Query: 249 QAMEDGMGKYGPECDWWSLGVCMYEM 274
                G   Y    D W  G  M EM
Sbjct: 241 L----GDRNYSTAIDQWGAGCIMAEM 306
>07833
          Length = 1504

 Score = 40.4 bits (93), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 27/99 (27%), Positives = 43/99 (43%)
 Frame = -3

Query: 209  DVNGHIRLADFGSCLKMNDDGTVQSSVAVGTPDYISPEILQAMEDGMGKYGPECDWWSLG 268
            D+   I +AD+  C   ++ G V S      P +++PE LQ   D +       D WS  
Sbjct: 1199 DLTARINMADY--CFSFHEKGKVYS------PAWMAPEALQRRPDDINTRA--ADMWSFA 1050

Query: 269  VCMYEMLYGETPFYAESLVETYGKIMNHEERFQFPSHVT 307
            + M+E+   E PF   S +E   K+     R   P  ++
Sbjct: 1049 ILMWELETREVPFAELSSMEVGMKVALEGLRISIPPGIS 933
>38560
          Length = 479

 Score = 40.4 bits (93), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 18/48 (37%), Positives = 27/48 (56%)
 Frame = -3

Query: 234 SVAVGTPDYISPEILQAMEDGMGKYGPECDWWSLGVCMYEMLYGETPF 281
           +   G+P Y +PE++  +E      G E D WS+GV +Y +L G  PF
Sbjct: 411 TTCCGSPAYAAPELISGLE----YLGSEADIWSMGVLLYALLCGYLPF 280
>32957
          Length = 645

 Score = 40.4 bits (93), Expect = 0.006,   Method: Composition-based stats.
 Identities = 16/41 (39%), Positives = 26/41 (63%)
 Frame = +3

Query: 238 GTPDYISPEILQAMEDGMGKYGPECDWWSLGVCMYEMLYGE 278
           GT +Y++PE+ +  E     YG E DWW LG+ ++E+L  +
Sbjct: 51  GTREYMAPEVHERKE-----YGKEVDWWGLGILLHELLAAQ 158
>37602
          Length = 804

 Score = 40.0 bits (92), Expect = 0.008,   Method: Composition-based stats.
 Identities = 23/71 (32%), Positives = 36/71 (50%)
 Frame = -1

Query: 149 LYLVMDYYVGGDLLTLLSKFEDKLPEDMARFYIGEMVLAIDSIHQLHYVHRDIKPDNVLL 208
           L++ M+Y  GG +  +       L E    F   E +  +  +H+   +HRDIK  N+LL
Sbjct: 294 LWIAMEYCGGGSMQDIY-HVTGPLTEPQIAFVCRETLKGLHYLHRRGKMHRDIKGANILL 118

Query: 209 DVNGHIRLADF 219
              G ++LADF
Sbjct: 117 TEEGDVKLADF 85
>32359
          Length = 928

 Score = 31.2 bits (69), Expect(2) = 0.015,   Method: Compositional matrix adjust.
 Identities = 31/121 (25%), Positives = 54/121 (44%), Gaps = 8/121 (6%)
 Frame = -1

Query: 80  KVIGRGAFGEVAVVKMRNTERIYAMKILNKWEMLKRAETACFREERDVLVNGDCQWITAL 139
           KVIG G+FG V   K+ +T  + A+K + + +  K  E    R+          Q I  L
Sbjct: 412 KVIGNGSFGVVYQAKLVDTSELVAIKKVLQDKRFKNRELQIMRKLEH-------QNIVKL 254

Query: 140 HYAF------QDENYLYLVMDYY--VGGDLLTLLSKFEDKLPEDMARFYIGEMVLAIDSI 191
            + F      +DE +L LV++Y       +    SK +  +P    + Y+ ++  ++  I
Sbjct: 253 KFFFYSSGEKKDEVFLNLVLEYVPETVYRVARHYSKSKQTIPILYIKLYMYQLFRSLAYI 74

Query: 192 H 192
           H
Sbjct: 73  H 71

 Score = 26.9 bits (58), Expect(2) = 0.015,   Method: Composition-based stats.
 Identities = 10/12 (83%), Positives = 11/12 (91%)
 Frame = -3

Query: 198 HRDIKPDNVLLD 209
           HRDIKP N+LLD
Sbjct: 56  HRDIKPQNLLLD 21
>07836
          Length = 1478

 Score = 38.9 bits (89), Expect = 0.016,   Method: Compositional matrix adjust.
 Identities = 39/142 (27%), Positives = 67/142 (47%), Gaps = 16/142 (11%)
 Frame = -1

Query: 149  LYLVMDYYVGGDLL-TLLSKFEDKLPEDMARFYIGEMVLAIDSIHQLHY----------- 196
            L+L+ DY+  G L   LLS+  D   E +A  +      AI  +  LH            
Sbjct: 1328 LFLITDYHENGSLHDYLLSRVLDS-SEMLALAHS-----AICGLAHLHIEIFGTRGKPAI 1167

Query: 197  VHRDIKPDNVLLDVNGHIRLADFGSCLKM---NDDGTVQSSVAVGTPDYISPEILQAMED 253
             HRDIK  N+L+  NG   +AD G  ++    +++  V  +   GT  Y++PE+L+ + +
Sbjct: 1166 AHRDIKSKNILVKKNGTCCIADLGLAVRYISESNEVDVAPNPRQGTKRYMAPEVLEMLLN 987

Query: 254  GMG-KYGPECDWWSLGVCMYEM 274
                    + D ++ G+ M+E+
Sbjct: 986  VKNFDAFKQADMYAFGLVMWEI 921
>28157
          Length = 400

 Score = 38.9 bits (89), Expect = 0.018,   Method: Compositional matrix adjust.
 Identities = 28/92 (30%), Positives = 49/92 (53%), Gaps = 6/92 (6%)
 Frame = +3

Query: 136 ITALHYAFQDENYLYLVMDYYVGGDLLTLL--SKFEDKLPEDMARFYIGEMVLAIDSIHQ 193
           I  L+ A +D   + LVM+Y  GG L  +L  S  + +     A  ++ +  L ++ +H 
Sbjct: 96  IVCLYGACRDHP-VCLVMEYAEGGSLYNVLHGSGPQPQYTAAHAMNWLLQCALGVEYLHG 272

Query: 194 LH---YVHRDIKPDNVLLDVNG-HIRLADFGS 221
           +     +HRD+KP N+LL   G  +++ DFG+
Sbjct: 273 MKPKALIHRDLKPPNLLLIQCGTKLKICDFGT 368
>20640
          Length = 1492

 Score = 38.5 bits (88), Expect = 0.021,   Method: Compositional matrix adjust.
 Identities = 30/107 (28%), Positives = 51/107 (47%)
 Frame = +1

Query: 196 YVHRDIKPDNVLLDVNGHIRLADFGSCLKMNDDGTVQSSVAVGTPDYISPEILQAMEDGM 255
           YVHRD+   N L+  +  ++++DFG    ++     + S     P    P  L+A+    
Sbjct: 7   YVHRDLATRNCLVGHDLVVKISDFGLARSVHSVDYYRGSEHDAIPIRWMP--LEAIL--Y 174

Query: 256 GKYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHEERFQF 302
            K+  + D WS GV ++E+       +A +L   YG  + HEE  +F
Sbjct: 175 NKFSTQSDVWSFGVVLWEI-------FAFALQPYYG--LTHEEVVRF 288
>15105
          Length = 367

 Score = 37.7 bits (86), Expect = 0.042,   Method: Composition-based stats.
 Identities = 25/67 (37%), Positives = 34/67 (50%)
 Frame = +1

Query: 1548 QMLRTRSKRRFVFKVPXXXXXXXXXXXXXDPELRSKMISNPTNFNHVAHMGPGDGMQVLM 1607
            Q   +R+KRRF FK                 + RS++IS P+NF+H+AHMG   G    +
Sbjct: 181  QEQSSRNKRRFSFK------SREDERSSNKGDRRSRIISPPSNFSHIAHMGA*PG-HAGL 339

Query: 1608 DLPLSAA 1614
            D P  AA
Sbjct: 340  DRPTQAA 360
>07291
          Length = 833

 Score = 37.4 bits (85), Expect = 0.057,   Method: Compositional matrix adjust.
 Identities = 23/94 (24%), Positives = 46/94 (48%), Gaps = 3/94 (3%)
 Frame = +1

Query: 191 IHQLHYVHRDIKPDNVLLDVNGHIRLADFG--SCLKMNDDGTVQSSVAVGTPDYISPEIL 248
           + ++  VHR++   N ++  +G ++L+D+G    L      T   S A     +++PE +
Sbjct: 97  LQEVKVVHRNLAARNCIVTEDGRLQLSDYGVTGSLFPQSYYTADDSPARDLVKWMAPETI 276

Query: 249 QAMEDGMGKYGPECDWWSLGVCMYEMLY-GETPF 281
                    +  + D W+ GV ++E+L  G TP+
Sbjct: 277 DNFH-----FSSKSDVWAFGVVLWELLTRGITPY 363
>26009
          Length = 886

 Score = 37.4 bits (85), Expect = 0.059,   Method: Compositional matrix adjust.
 Identities = 15/32 (46%), Positives = 23/32 (71%)
 Frame = +3

Query: 177 ARFYIGEMVLAIDSIHQLHYVHRDIKPDNVLL 208
           A+  + ++V A+D +H    VHRDIKP+NVL+
Sbjct: 717 AKSVMKQLVSALDFMHSKQLVHRDIKPENVLI 812
>19301
          Length = 712

 Score = 37.0 bits (84), Expect = 0.067,   Method: Compositional matrix adjust.
 Identities = 18/71 (25%), Positives = 40/71 (56%)
 Frame = +2

Query: 151 LVMDYYVGGDLLTLLSKFEDKLPEDMARFYIGEMVLAIDSIHQLHYVHRDIKPDNVLLDV 210
           ++M+Y   G L  +L   ++ +P  +   +  ++   ++ +H    +HRD+K  NVL+  
Sbjct: 500 IIMEYCPYGQLYEVLRDGKE-IPPALVLDWSKQIASGMNYLHSHKIIHRDLKSPNVLVAK 676

Query: 211 NGHIRLADFGS 221
           N  ++++DFG+
Sbjct: 677 NDVVKISDFGT 709
>18481
          Length = 437

 Score = 36.2 bits (82), Expect = 0.10,   Method: Composition-based stats.
 Identities = 16/48 (33%), Positives = 29/48 (60%), Gaps = 3/48 (6%)
 Frame = -1

Query: 183 EMVLAIDSIHQLHYVHRDIKPDNVLLDVNGH---IRLADFGSCLKMND 227
           +++  ++ IHQ  ++HRD+KPDN L+ +  H   + + DFG   +  D
Sbjct: 173 QLLSRLEFIHQKCFIHRDLKPDNFLMGLGRHCHRLYIIDFGLSKRYKD 30
>02638
          Length = 1490

 Score = 36.2 bits (82), Expect = 0.12,   Method: Composition-based stats.
 Identities = 22/85 (25%), Positives = 37/85 (43%)
 Frame = +1

Query: 237 VGTPDYISPEILQAMEDGMGKYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNH 296
           +GT  +++PE+L+        YG  CD WS+G  M EM     P+ +  +      I   
Sbjct: 19  LGTIAFMAPEVLRGES-----YGRACDVWSVGCVMIEMCTCRPPWNSHDISNHLALIFKI 183

Query: 297 EERFQFPSHVTDVSEEAKDLIQRLI 321
                 P    ++S   +DL+ R +
Sbjct: 184 ASSVDPPPIPENMSPPVRDLMLRCL 258
>09007
          Length = 1440

 Score = 35.4 bits (80), Expect = 0.18,   Method: Compositional matrix adjust.
 Identities = 45/219 (20%), Positives = 93/219 (42%), Gaps = 17/219 (7%)
 Frame = -1

Query: 80  KVIGRGAFGEV--AVVKMRNTERI-YAMKILNKWEMLKRAETACFREERDVLVNGDCQWI 136
           K +G+G FG V  A+    + E++  A+K L+K ++ K  +   F +E  ++   D + I
Sbjct: 861 KSLGQGHFGTVRQAIWTAESGEKVQVAVKCLSKDKIHKDGQE--FLKETAIMQMLDHENI 688

Query: 137 TALHYAFQDENY-LYLVMDYYVGGDLLTLLSKFEDKLPEDMARF--YIGEMVLAIDSIHQ 193
             ++    D    + LV +      LL  + +   ++   + R   +  ++   +  +  
Sbjct: 687 VRVYGVVMDNGADIMLVTELAPMRSLLECVKEVSARVDFSVPRLCDFSQQVCDGMSYLES 508

Query: 194 LHYVHRDIKPDNVLLDVNGHIRLADFGSCLKMNDDGTVQSSVAVGTPDYISPEILQAMED 253
              VHRD+   N+LL     ++++D G          V  ++  G   Y S + +  +++
Sbjct: 507 KRLVHRDLAARNILLFSKSKVKISDVG----------VSGALGAGKEYYQSQQTIH-LQN 361

Query: 254 GMGKYGPE----------CDWWSLGVCMYEML-YGETPF 281
            +    PE           D W+ GV ++E   +G  P+
Sbjct: 360 AVAWCAPESFRNLCFSSASDVWAFGVLLWEFFTHGFQPW 244
>01106
          Length = 878

 Score = 35.0 bits (79), Expect = 0.23,   Method: Compositional matrix adjust.
 Identities = 39/159 (24%), Positives = 73/159 (45%), Gaps = 13/159 (8%)
 Frame = +3

Query: 66  VKDMQLHREDFEIIKVIGRGAFGEVAVVKMRNTERIYAMKILNKWEMLKRAETA------ 119
           VK+  L    + +I+ +G G F  V +      +R  A+K++   +     ETA      
Sbjct: 294 VKNGDLFNGRYHVIRKLGWGHFSTVWLCWDLTCKRFVALKVVKSAQHY--TETALDEVKL 467

Query: 120 --CFREERDVLVNGDCQWITALH-YAFQDENYLYLVMDYYV-GGDLLTLL--SKFEDKLP 173
             C RE  DV      + +  L  +     N  ++ M + V G +LL L+  S ++  +P
Sbjct: 468 LKCVRES-DVADPARAKCVQLLDDFKISGVNGTHVAMVFEVLGYNLLKLIIRSNYQG-IP 641

Query: 174 EDMARFYIGEMVLAIDSIH-QLHYVHRDIKPDNVLLDVN 211
               +  I +++  +  +H +   +H DIKP+N+L+ V+
Sbjct: 642 IHNVKLIIRQVLEGLSYMHAKCRIIHTDIKPENILICVD 758
>07940
          Length = 1336

 Score = 35.0 bits (79), Expect = 0.28,   Method: Compositional matrix adjust.
 Identities = 30/124 (24%), Positives = 57/124 (45%), Gaps = 2/124 (1%)
 Frame = -3

Query: 160 DLLTLLSKFEDKLPEDMARFYIGEMVLAIDSIHQLHYVHRDIKPDNVLLDVNGHIRLADF 219
           D+L +L+      P+D+   Y  ++   ++ +     +HRD+   NVL+     +++ADF
Sbjct: 371 DMLKMLT------PKDLIS-YAYQVARGMEYLASKQCIHRDLAARNVLVAEEYVLKIADF 213

Query: 220 GSCLKMNDDGTVQSSVAVGTP-DYISPEILQAMEDGMGKYGPECDWWSLGVCMYEML-YG 277
           G    +      + +     P  +++PE L        KY  + D WS GV ++E+   G
Sbjct: 212 GLTRNLQQFDYYRKTTDGRLPVKWMAPEALFDR-----KYTSKSDVWSYGVLLWEIFTLG 48

Query: 278 ETPF 281
             P+
Sbjct: 47  GNPY 36
>00638
          Length = 1595

 Score = 34.7 bits (78), Expect = 0.39,   Method: Composition-based stats.
 Identities = 19/59 (32%), Positives = 32/59 (54%)
 Frame = +2

Query: 151 LVMDYYVGGDLLTLLSKFEDKLPEDMARFYIGEMVLAIDSIHQLHYVHRDIKPDNVLLD 209
           L+ ++    D   L   F D    D+ RFY+ E++ A+D  H +  +HRD+KP   L++
Sbjct: 356 LIFEHVNNTDFKQLYQTFTDY---DI-RFYLYELMKALDFCHSMGIMHRDVKPSPPLVN 520
>17516
          Length = 453

 Score = 34.3 bits (77), Expect = 0.48,   Method: Composition-based stats.
 Identities = 15/41 (36%), Positives = 26/41 (63%)
 Frame = -3

Query: 238 GTPDYISPEILQAMEDGMGKYGPECDWWSLGVCMYEMLYGE 278
           GTP Y++PE+L       G+Y  + D +SL + ++E+ YG+
Sbjct: 433 GTPVYMAPEVLLQK----GQYDMKADVYSLAIILWELWYGQ 323
>31489
          Length = 329

 Score = 34.3 bits (77), Expect = 0.51,   Method: Composition-based stats.
 Identities = 13/39 (33%), Positives = 25/39 (64%)
 Frame = +3

Query: 169 EDKLPEDMARFYIGEMVLAIDSIHQLHYVHRDIKPDNVL 207
           +  L E+  R+++ +++  +  IH  + VHRD+KP N+L
Sbjct: 147 DQPLTEEHIRYFLYQILRGLKYIHSANVVHRDLKPSNLL 263
>18401
          Length = 463

 Score = 33.9 bits (76), Expect = 0.54,   Method: Compositional matrix adjust.
 Identities = 18/48 (37%), Positives = 26/48 (54%)
 Frame = -3

Query: 234 SVAVGTPDYISPEILQAMEDGMGKYGPECDWWSLGVCMYEMLYGETPF 281
           S  V T  Y +PE++  +E G   +   CD WS+G  M+E+  G T F
Sbjct: 458 STIVSTRHYRAPEVI--LELG---WSHPCDVWSVGCIMFELYTGYTLF 330
>11780
          Length = 1713

 Score = 33.1 bits (74), Expect = 0.92,   Method: Compositional matrix adjust.
 Identities = 38/148 (25%), Positives = 69/148 (46%), Gaps = 1/148 (0%)
 Frame = +3

Query: 74  EDFEIIKVIGRGAFGEVAVVKMRNTERIYAMKILNKWEMLKRAETACFREERDVLVNGDC 133
           +D EI + IG+G FG+V     R      A+K L   +   R E + F +E  V+ +   
Sbjct: 597 QDLEIGEAIGKGDFGDVYKGMYRGQP--VAIKQLKDKD---RGEQS-FLQEASVMTSLRH 758

Query: 134 QWITALHYAFQDENYLYLVMDYYVGGDLLTLL-SKFEDKLPEDMARFYIGEMVLAIDSIH 192
             +  L      E  ++LV ++   G+L+  L S+    + +     +  +   A++ + 
Sbjct: 759 DNLVRLIGVVLGET-IFLVTEFMGKGNLVEYLRSRGRSVITKKDQINFATDTCAAMEYLE 935

Query: 193 QLHYVHRDIKPDNVLLDVNGHIRLADFG 220
               VHRD+   NVL+  +G  +++DFG
Sbjct: 936 SKRLVHRDLAARNVLVHDDGKAKVSDFG 1019
>09986
          Length = 2844

 Score = 33.1 bits (74), Expect = 1.1,   Method: Composition-based stats.
 Identities = 17/45 (37%), Positives = 19/45 (42%)
 Frame = +3

Query: 998  DMARPQQRPSPVPLPSTQALAMAGPKPKAHQFSIKSFPSPTQCSH 1042
            DM RP  R S +P+P         PKP  HQ      PSP    H
Sbjct: 2418 DMTRPGDRRSNLPIPKQT------PKPLGHQVGYARHPSPVVFRH 2534
>06101
          Length = 1773

 Score = 32.0 bits (71), Expect = 2.0,   Method: Composition-based stats.
 Identities = 27/89 (30%), Positives = 32/89 (35%), Gaps = 8/89 (8%)
 Frame = -2

Query: 1005 RPSPVPLPSTQALAMAGPKPKAHQFSIKSFPSPTQCSHCTSLMVGLIRQGYACEV----- 1059
            RPS  P P  Q+L  A P P          PSP  C    S + G  R G    +     
Sbjct: 1031 RPSNDPAPFPQSLVSAEPVP--------GIPSPATCCREPSPLQGRSRXGDPTPLHHTRX 876

Query: 1060 ---CAFSCHVSCKDSAPQVCPIPPEQSKR 1085
               C + C V C    P+    PP Q  R
Sbjct: 875  PATCCYRCSV-CH*RCPRRSGXPPPQCSR 792
>37902
          Length = 474

 Score = 32.0 bits (71), Expect = 2.1,   Method: Composition-based stats.
 Identities = 17/41 (41%), Positives = 21/41 (51%)
 Frame = -2

Query: 1005 RPSPVPLPSTQALAMAGPKPKAHQFSIKSFPSPTQCSHCTS 1045
            R    PL  ++ALA  GP      FS+ SFP+   C  CTS
Sbjct: 134  RGGVAPLTPSRALAAPGP----CHFSVFSFPNSPACLFCTS 24
>29360
          Length = 363

 Score = 30.8 bits (68), Expect = 4.7,   Method: Compositional matrix adjust.
 Identities = 21/69 (30%), Positives = 38/69 (55%), Gaps = 2/69 (2%)
 Frame = +3

Query: 142 AFQDENYLYLVMDYYVGGDLLTLL--SKFEDKLPEDMARFYIGEMVLAIDSIHQLHYVHR 199
            FQ +N+  LV +  +  +L   L  +KF+  LP    R    +++ A+  + QL  +H 
Sbjct: 159 CFQHKNHTCLVFEM-LEQNLYDFLKQNKFQP-LPLKYIRPITQQVLTALRKLKQLGLIHA 332

Query: 200 DIKPDNVLL 208
           D+KP+N++L
Sbjct: 333 DLKPENIML 359
>30339
          Length = 384

 Score = 30.4 bits (67), Expect = 6.4,   Method: Composition-based stats.
 Identities = 11/27 (40%), Positives = 19/27 (70%)
 Frame = -2

Query: 70 QLHREDFEIIKVIGRGAFGEVAVVKMR 96
          + H  DF  IKV+G+G+FG+V + + +
Sbjct: 86 RFHLHDFNFIKVLGKGSFGKVMLAERK 6
>11404
          Length = 563

 Score = 30.0 bits (66), Expect = 8.7,   Method: Compositional matrix adjust.
 Identities = 39/152 (25%), Positives = 59/152 (38%), Gaps = 19/152 (12%)
 Frame = +1

Query: 76  FEIIKVIGRGAFGEVAVVKMRNTERIYAMKIL-NK-------------WEMLKRAET--- 118
           +EI  +IG+G+FG+V            A+KI+ NK              EM+ R +T   
Sbjct: 145 YEIDSLIGKGSFGQVVKAYDHTDNEQVAIKIIKNKKPFLNQAQIEVKLLEMMNRHDTDNK 324

Query: 119 -ACFREERDVLVNGD-CQWITALHYAFQDENYLYLVMDYYVGGDLLTLLSKFEDKLPEDM 176
               R +R  +     C     L Y   D     L+ +    G  L L  KF  +L   +
Sbjct: 325 YYIVRLKRHFMFRSHLCLVFELLSYNLYD-----LLRNTNFRGVSLNLTRKFAQQLCTAL 489

Query: 177 ARFYIGEMVLAIDSIHQLHYVHRDIKPDNVLL 208
                 EM +          +H D+KP+N+LL
Sbjct: 490 LFLATPEMSI----------IHCDLKPENILL 555
>09344
          Length = 1203

 Score = 30.0 bits (66), Expect = 9.4,   Method: Compositional matrix adjust.
 Identities = 24/75 (32%), Positives = 42/75 (56%), Gaps = 7/75 (9%)
 Frame = +1

Query: 866 RRSQKLDMSARLELQSALEAEIRAKQLVQEELRKVKDSSLAFESKLKESEAKNR------ 919
           R ++ LD   +L+L+  ++  ++  QL  + LR+VKD +   ES L E EAK        
Sbjct: 421 RYTKVLDTIRKLKLEKEVDIRVKWDQL--KLLRQVKDKTTQLESDLAELEAKWESTKVSV 594

Query: 920 -ELLEEMQSLRKRME 933
            +L ++M  +R+R+E
Sbjct: 595 TQLSDQMTPVRERLE 639
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6681225|ref|NP_031905.1| developmentally regulated
GTP binding protein 1 [Mus musculus]
         (367 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

17271                                                                 288   2e-79
22318                                                                 177   9e-67
32772                                                                  76   1e-24
18173                                                                  48   7e-06
20257                                                                  39   0.003
14433                                                                  37   0.017
00817                                                                  33   0.18 
20319                                                                  31   1.0  
14546                                                                  29   3.1  
>17271
          Length = 566

 Score =  288 bits (737), Expect(2) = 2e-79,   Method: Compositional matrix adjust.
 Identities = 142/178 (79%), Positives = 156/178 (87%)
 Frame = -2

Query: 65  ARIGFVGFPSVGKSTLLSNLAGVYSEVAAYEFTTLTTVPGVIRYKGAKIQLLDLPGIIEG 124
           + + FVGFPSVGKSTLLSNLAGVYSEVAAYEFTTLTTVPGVIRYKGAKIQLLDLPGIIEG
Sbjct: 535 SNLDFVGFPSVGKSTLLSNLAGVYSEVAAYEFTTLTTVPGVIRYKGAKIQLLDLPGIIEG 356

Query: 125 AKDGKGRGRQVIAVARTCNLILIVLDVLKPLGHKKIIENELEGFGIRLNSKPPNIGFKKK 184
           AKDGKGRG+QVIAVARTC LI IVLD LKPL HK +IE+ELEGFGIRLN +PPNI FKKK
Sbjct: 355 AKDGKGRGKQVIAVARTCGLIFIVLDCLKPLQHKNLIEHELEGFGIRLNKEPPNIVFKKK 176

Query: 185 DKGGINLTATCPQSELDAETVKSILAEYKIHNADVTLRSDATADDLIDVVEGNRVYIP 242
           +KGG+NL     QSELD +TV++IL EYKIHNAD+TLR DATA+DLIDV+EG     P
Sbjct: 175 EKGGLNLQTMVSQSELDLDTVRTILGEYKIHNADITLRYDATAEDLIDVIEGTESTSP 2

 Score = 25.8 bits (55), Expect(2) = 2e-79,   Method: Compositional matrix adjust.
 Identities = 11/11 (100%), Positives = 11/11 (100%)
 Frame = -3

Query: 57  FDVAKTGDARI 67
           FDVAKTGDARI
Sbjct: 561 FDVAKTGDARI 529
>22318
          Length = 808

 Score =  177 bits (449), Expect(3) = 9e-67,   Method: Compositional matrix adjust.
 Identities = 88/131 (67%), Positives = 102/131 (77%)
 Frame = +3

Query: 57  FDVAKTGDARIGFVGFPSVGKSTLLSNLAGVYSEVAAYEFTTLTTVPGVIRYKGAKIQLL 116
           FDV K+GDAR+  +GFPSVGKSTLLS L    SE AAYEFTTLT +PGVI Y GA IQLL
Sbjct: 216 FDVMKSGDARVALIGFPSVGKSTLLSTLTKTESECAAYEFTTLTCIPGVIEYAGANIQLL 395

Query: 117 DLPGIIEGAKDGKGRGRQVIAVARTCNLILIVLDVLKPLGHKKIIENELEGFGIRLNSKP 176
           DLPGIIEGA  GKGRGRQVIAVART +LI+I+LD  K    K+++E ELE  GIRLN + 
Sbjct: 396 DLPGIIEGAAQGKGRGRQVIAVARTADLIIIMLDATKGDVQKELLEKELEAVGIRLNREK 575

Query: 177 PNIGFKKKDKG 187
           PNI FK++ +G
Sbjct: 576 PNIYFKQRKEG 608

 Score = 80.5 bits (197), Expect(3) = 9e-67,   Method: Compositional matrix adjust.
 Identities = 36/71 (50%), Positives = 50/71 (70%)
 Frame = +1

Query: 184 KDKGGINLTATCPQSELDAETVKSILAEYKIHNADVTLRSDATADDLIDVVEGNRVYIPC 243
           K++ GI+  AT   ++   + V+ IL EYKI NA+V  R D T+D+ +DV+ GNR Y+PC
Sbjct: 595 KERRGISFNATLTLTKCSEKMVQLILHEYKIFNAEVLFRDDCTSDEFVDVILGNRAYMPC 774

Query: 244 IYVLNKIDQIS 254
           +YV NKIDQIS
Sbjct: 775 LYVYNKIDQIS 807

 Score = 35.4 bits (80), Expect(3) = 9e-67,   Method: Compositional matrix adjust.
 Identities = 16/22 (72%), Positives = 19/22 (86%)
 Frame = +2

Query: 3  GTLAKIAEIEAEMARTQKNKAT 24
          G L +IAE+E E+ARTQKNKAT
Sbjct: 56 GYLGEIAEVEREIARTQKNKAT 121
>32772
          Length = 444

 Score = 76.3 bits (186), Expect(2) = 1e-24,   Method: Compositional matrix adjust.
 Identities = 33/47 (70%), Positives = 39/47 (82%)
 Frame = +3

Query: 321 FCMKIHKNLIKEFKYALVWGLSVKHNPQKVGKDHTLEDEDVIQIVKK 367
            C K+H+ +IKEFKYALVWG SVKH PQ VGK+H L DEDV+QI+KK
Sbjct: 90  LCNKLHRTIIKEFKYALVWGTSVKHCPQNVGKEHVLNDEDVVQILKK 230

 Score = 55.1 bits (131), Expect(2) = 1e-24,   Method: Compositional matrix adjust.
 Identities = 26/31 (83%), Positives = 27/31 (87%)
 Frame = +1

Query: 291 LVRIYTKPKGQLPDYTSPVVLPYSRTTVEDF 321
           LVRIYTKPKGQLPDYTSPVVL    +TVEDF
Sbjct: 1   LVRIYTKPKGQLPDYTSPVVLKDGHSTVEDF 93
>18173
          Length = 1308

 Score = 47.8 bits (112), Expect = 7e-06,   Method: Compositional matrix adjust.
 Identities = 29/104 (27%), Positives = 53/104 (50%), Gaps = 2/104 (1%)
 Frame = +2

Query: 67  IGFVGFPSVGKSTLLSNLAGVYSEVAAYEFTTLTTVPGVIRYKGAKIQLLDLPGIIEGAK 126
           I   GFP+VGKS+ ++ +     EV  Y FTT +   G   YK  + Q++D PGI++   
Sbjct: 557 IIICGFPNVGKSSFINKVTNADVEVQPYAFTTKSLYVGHTDYKFNRYQVIDTPGILDHPM 736

Query: 127 DGKG--RGRQVIAVARTCNLILIVLDVLKPLGHKKIIENELEGF 168
           +       + + A+     ++L V+D+ +    +K +E ++  F
Sbjct: 737 EDMNTIEMQAITALTHLKAIVLYVMDLSQQC--QKTVEEQVSLF 862
>20257
          Length = 757

 Score = 39.3 bits (90), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 24/101 (23%), Positives = 47/101 (46%), Gaps = 17/101 (16%)
 Frame = +1

Query: 66  RIGFVGFPSVGKSTLLSNLAGVYSEVAAYEFTTLTTVPGVI-----RYK----------- 109
           RIG +G P+VGKS+  + L    +    + F T+      +     R++           
Sbjct: 127 RIGILGLPNVGKSSFFNVLTKNAAPAENFPFCTIDPNESRVPVPDKRWEFLCDYFQPASK 306

Query: 110 -GAKIQLLDLPGIIEGAKDGKGRGRQVIAVARTCNLILIVL 149
             A + ++D+ G+++GA +GKG G   ++    C+ +  V+
Sbjct: 307 VPAYLNVVDIAGLVKGAHEGKGLGNAFLSNINACDAMFHVV 429
>14433
          Length = 520

 Score = 36.6 bits (83), Expect = 0.017,   Method: Compositional matrix adjust.
 Identities = 28/97 (28%), Positives = 44/97 (45%), Gaps = 5/97 (5%)
 Frame = +3

Query: 66  RIGFVGFPSVGKSTLLSNLAGVYSEVAAYEFTTLTTVPGVIRYKGA-----KIQLLDLPG 120
           R+G VGFP+ GKS+++++L          +  T+   PGV R          I+LLD PG
Sbjct: 9   RVGIVGFPNTGKSSIINSL-------KRSKACTVGATPGVTRAMQEVNLDKHIKLLDSPG 167

Query: 121 IIEGAKDGKGRGRQVIAVARTCNLILIVLDVLKPLGH 157
           ++            V AV R    +  + D + P+ H
Sbjct: 168 VVMETSQSP-----VTAVLRNVVRLESIEDPVAPVQH 263
>00817
          Length = 2606

 Score = 33.1 bits (74), Expect = 0.18,   Method: Compositional matrix adjust.
 Identities = 18/64 (28%), Positives = 33/64 (51%), Gaps = 8/64 (12%)
 Frame = +3

Query: 67  IGFVGFPSVGKSTLLSNL--------AGVYSEVAAYEFTTLTTVPGVIRYKGAKIQLLDL 118
           +G +G+P+VGKS++++ L        A +  E   +++ TL            +I L+D 
Sbjct: 615 VGLIGYPNVGKSSIINALKAKKVCKVAPLAGETKVWQYVTLMK----------RIYLVDC 764

Query: 119 PGII 122
           PGI+
Sbjct: 765 PGIV 776
>20319
          Length = 1200

 Score = 30.8 bits (68), Expect = 1.0,   Method: Compositional matrix adjust.
 Identities = 12/20 (60%), Positives = 17/20 (85%)
 Frame = +1

Query: 67  IGFVGFPSVGKSTLLSNLAG 86
           IG +G+P+VGKS+LL+ L G
Sbjct: 433 IGCIGYPNVGKSSLLNGLVG 492
>14546
          Length = 707

 Score = 28.9 bits (63), Expect = 3.1,   Method: Compositional matrix adjust.
 Identities = 13/27 (48%), Positives = 17/27 (62%)
 Frame = +2

Query: 293 RIYTKPKGQLPDYTSPVVLPYSRTTVE 319
           R+Y + KG LPD+   V+LP S   VE
Sbjct: 68  RLYNQLKGDLPDFVKIVLLPKSGGVVE 148
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6753074|ref|NP_033809.1| adaptor protein complex
AP-2, mu1 [Mus musculus]
         (435 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

30493                                                                 264   2e-79
04701                                                                 286   1e-77
08361                                                                 267   6e-72
06056                                                                 220   9e-58
28998                                                                  80   2e-15
29016                                                                  77   2e-14
04375                                                                  33   0.30 
12720                                                                  29   4.7  
02680                                                                  28   7.5  
01059                                                                  28   8.8  
>30493
          Length = 657

 Score =  264 bits (674), Expect(2) = 2e-79,   Method: Compositional matrix adjust.
 Identities = 122/142 (85%), Positives = 134/142 (94%)
 Frame = -2

Query: 294 REVGRTKLEVKVVIKSNFKPSLLAQKIEVRIPTPLNTSGVQVICMKGKAKYKASENAIVW 353
           REVGR K+EVKVV+KSNFKPSL AQK+E+RIPTPLNTSGVQVICMKG+AKYKAS+NAIVW
Sbjct: 581 REVGRQKMEVKVVVKSNFKPSLAAQKVELRIPTPLNTSGVQVICMKGRAKYKASDNAIVW 402

Query: 354 KIKRMAGMKESQISAEIELLPTNDKKKWARPPISMNFEVPFAPSGLKVRYLKVFEPKLNY 413
           KIKR+ GMKE Q+SAEIELL T+DKKKW RPP+SMNFEVPFAPSG KVRYLKVFE K+NY
Sbjct: 401 KIKRIGGMKECQLSAEIELLATSDKKKWTRPPLSMNFEVPFAPSGFKVRYLKVFESKINY 222

Query: 414 SDHDVIKWVRYIGRSGIYETRC 435
           SDHDVIKWVRYIGRSG+YETRC
Sbjct: 221 SDHDVIKWVRYIGRSGLYETRC 156

 Score = 50.8 bits (120), Expect(2) = 2e-79,   Method: Compositional matrix adjust.
 Identities = 23/31 (74%), Positives = 24/31 (77%)
 Frame = -3

Query: 268 PDGEFELMRYRTTKDIILPFRVIPLVREVGR 298
           P  EFELMRYRTT DI LPFRVIP+ R  GR
Sbjct: 655 P*REFELMRYRTTNDISLPFRVIPVARSAGR 563

 Score = 33.1 bits (74), Expect = 0.20,   Method: Compositional matrix adjust.
 Identities = 14/18 (77%), Positives = 15/18 (83%)
 Frame = -3

Query: 418 VIKWVRYIGRSGIYETRC 435
           VIKWV  IG SG+YETRC
Sbjct: 82  VIKWV*CIGXSGLYETRC 29
>04701
          Length = 4543

 Score =  286 bits (732), Expect = 1e-77,   Method: Compositional matrix adjust.
 Identities = 147/355 (41%), Positives = 215/355 (60%), Gaps = 1/355 (0%)
 Frame = +2

Query: 81  FLYKMCDVMAAYFGKISEENIKNNFVLIYELLDEILDFGYPQNSETGALKTFITQQGIKS 140
           F  + C     YF ++ EE+I++NFV+IYELLDE++DFGYPQ +++  L+ +ITQ+G   
Sbjct: 332 FPPQACADFVEYFKELEEESIRDNFVIIYELLDEVMDFGYPQTTDSKILQEYITQEG--- 502

Query: 141 QHQTKEEQSQITSQVTGQIGWRREGIKYRRNELFLDVLESVNLLMSPQGQVLSAHVSGRV 200
             Q  E   +    VT  + WR EG+KYR+NE+FLDV+ESVNLL+S  G VL + + G V
Sbjct: 503 --QKLEVAPRPPMAVTNAVSWRSEGVKYRKNEVFLDVIESVNLLVSANGNVLRSEIVGSV 676

Query: 201 VMKSYLSGMPECKFGMNDKIVIEKQGKGTADETSKSGKQSIAIDDCTFHQCVRLSKFDSE 260
            M+ +LSGMPE + G+NDK++ E  G+G +        +S+ ++D  FHQCVRLS+F+++
Sbjct: 677 KMRVFLSGMPELRLGLNDKVLFESTGRGKS--------KSVELEDVKFHQCVRLSRFEND 832

Query: 261 RSISFIPPDGEFELMRYRTTKDIILPFRVIPLVREVGRTKLEVKVVIKSNFKPSLLAQKI 320
           R+ISFIPPDGEFELM YR    +     V  ++     +++E  +  KS FK    A  +
Sbjct: 833 RTISFIPPDGEFELMSYRLNTHVKPLIWVESVIERHVHSRVEYMIKAKSQFKRRSTANNV 1012

Query: 321 EVRIPTPLNTSGVQVICMKGKAKYKASENAIVWKIKRMAGMKESQISAEIELLPTNDKKK 380
           E+ IP P +    +     G  KY    N+++W IK   G KE  + A   L    ++  
Sbjct: 1013EIIIPVPADADSPKFKTTVGSCKYVPEINSVIWSIKSFPGGKEFLMRAHFGLPSVENEDA 1192

Query: 381 WARPPISMNFEVP-FAPSGLKVRYLKVFEPKLNYSDHDVIKWVRYIGRSGIYETR 434
             RPPIS+ FE+P F  SG++VRYLK+ E     S +  + WVRYI ++G Y+ R
Sbjct: 1193EGRPPISIKFEIPYFTVSGIQVRYLKIIEK----SGYQALPWVRYITQNGDYQLR 1345
>08361
          Length = 465

 Score =  267 bits (683), Expect = 6e-72,   Method: Compositional matrix adjust.
 Identities = 125/153 (81%), Positives = 144/153 (94%)
 Frame = -3

Query: 79  FEFLYKMCDVMAAYFGKISEENIKNNFVLIYELLDEILDFGYPQNSETGALKTFITQQGI 138
           FEFL+K+ +VM AYFGKISEENIKNNFVLIYE+LDEILD+GYPQN++TG LKTFITQQGI
Sbjct: 463 FEFLHKIAEVMQAYFGKISEENIKNNFVLIYEILDEILDYGYPQNTDTGILKTFITQQGI 284

Query: 139 KSQHQTKEEQSQITSQVTGQIGWRREGIKYRRNELFLDVLESVNLLMSPQGQVLSAHVSG 198
           KSQ  +KE+ +QITSQVTGQIGWRREGIKYRRNELFLDVLESVNLLMSPQGQVLSAHV+G
Sbjct: 283 KSQ--SKEDTAQITSQVTGQIGWRREGIKYRRNELFLDVLESVNLLMSPQGQVLSAHVAG 110

Query: 199 RVVMKSYLSGMPECKFGMNDKIVIEKQGKGTAD 231
           R+VMKSYLSGMPECKFG+NDK++++ +GK T +
Sbjct: 109 RIVMKSYLSGMPECKFGINDKVLMDTKGKSTLE 11
>06056
          Length = 1228

 Score =  220 bits (560), Expect = 9e-58,   Method: Compositional matrix adjust.
 Identities = 104/122 (85%), Positives = 113/122 (92%)
 Frame = -2

Query: 267  PPDGEFELMRYRTTKDIILPFRVIPLVREVGRTKLEVKVVIKSNFKPSLLAQKIEVRIPT 326
            PPDGEFELMRYRTT DI LPFRVIPLVREVGR K+EVKVV+KSNFKPSL AQK+E+RIPT
Sbjct: 1104 PPDGEFELMRYRTTNDISLPFRVIPLVREVGRQKMEVKVVVKSNFKPSLAAQKVELRIPT 925

Query: 327  PLNTSGVQVICMKGKAKYKASENAIVWKIKRMAGMKESQISAEIELLPTNDKKKWARPPI 386
            PLNTSGVQVICMKG AKYKAS+NAIVWKIKR+ GMKE Q+SAEIELL T+DKKKW RPP+
Sbjct: 924  PLNTSGVQVICMKGXAKYKASDNAIVWKIKRIGGMKECQLSAEIELLATSDKKKWTRPPL 745

Query: 387  SM 388
            SM
Sbjct: 744  SM 739

 Score = 63.9 bits (154), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 35/77 (45%), Positives = 46/77 (59%), Gaps = 4/77 (5%)
 Frame = -3

Query: 226  GKGTADETSKSGKQSIAIDDCTFHQCVRLSKFDSERSISFIPPDGEF---ELMRYRTTKD 282
            G G+    + +GK SIAIDDC FHQCV+LSKF++E SISFIP  G     +++R  T+  
Sbjct: 1226 GSGSTVSGAGAGKTSIAIDDCQFHQCVKLSKFETEHSISFIPLXGNLNS*DIVRRMTS-- 1053

Query: 283  IILPFRVIPL-VREVGR 298
             +      PL  R  GR
Sbjct: 1052 -VCHSESFPLFARSAGR 1005
>28998
          Length = 569

 Score = 79.7 bits (195), Expect = 2e-15,   Method: Compositional matrix adjust.
 Identities = 35/45 (77%), Positives = 39/45 (86%)
 Frame = +2

Query: 236 SGKQSIAIDDCTFHQCVRLSKFDSERSISFIPPDGEFELMRYRTT 280
           +GK SIAIDDC FHQCV+LSKF++E SISFIPPDGEFELMR   T
Sbjct: 8   AGKTSIAIDDCQFHQCVKLSKFETEHSISFIPPDGEFELMRVYPT 142
>29016
          Length = 550

 Score = 77.0 bits (188), Expect = 2e-14,   Method: Compositional matrix adjust.
 Identities = 33/40 (82%), Positives = 37/40 (92%)
 Frame = +2

Query: 236 SGKQSIAIDDCTFHQCVRLSKFDSERSISFIPPDGEFELM 275
           +GK SIAIDDC FHQCV+LSKF++E SISFIPPDGEFELM
Sbjct: 8   AGKTSIAIDDCQFHQCVKLSKFETEHSISFIPPDGEFELM 127
>04375
          Length = 2667

 Score = 32.7 bits (73), Expect = 0.30,   Method: Compositional matrix adjust.
 Identities = 17/86 (19%), Positives = 40/86 (46%)
 Frame = +3

Query: 59  KRSNIWLAAVTKQNVNAAMVFEFLYKMCDVMAAYFGKISEENIKNNFVLIYELLDEILDF 118
           + ++++     +   N  +  E +++  +++  YFG + E +I  NF   + +LDE +  
Sbjct: 282 RYASLYFCCAIEPEDNELLTLEIIHRYVELLDKYFGSVCELDIIFNFEKAFFMLDEFMLG 461

Query: 119 GYPQNSETGALKTFITQQGIKSQHQT 144
           G  Q +    +   I  Q +  + +T
Sbjct: 462 GEVQETSKKNVLKAIAAQDLLQEEET 539
>12720
          Length = 850

 Score = 28.9 bits (63), Expect = 4.7,   Method: Compositional matrix adjust.
 Identities = 11/28 (39%), Positives = 16/28 (57%)
 Frame = -3

Query: 408 EPKLNYSDHDVIKWVRYIGRSGIYETRC 435
           E KL Y+  D +K   ++GR  +YE  C
Sbjct: 512 EDKLEYASQDALKISEWVGRRSVYEHLC 429
>02680
          Length = 1134

 Score = 28.1 bits (61), Expect = 7.5,   Method: Compositional matrix adjust.
 Identities = 9/16 (56%), Positives = 12/16 (75%)
 Frame = -3

Query: 409 PKLNYSDHDVIKWVRY 424
           PK NYSDHD++ W  +
Sbjct: 607 PKGNYSDHDLVAWAYF 560
>01059
          Length = 481

 Score = 27.7 bits (60), Expect = 8.8,   Method: Compositional matrix adjust.
 Identities = 9/16 (56%), Positives = 12/16 (75%)
 Frame = +1

Query: 409 PKLNYSDHDVIKWVRY 424
           PK NYSDHD++ W  +
Sbjct: 142 PKGNYSDHDLVAWTYF 189
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6754976|ref|NP_035164.1| peroxiredoxin 1 [Mus
musculus]
         (199 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

10721                                                                 290   2e-79
09130                                                                 283   3e-77
09123                                                                  75   2e-14
10713                                                                  28   2.0  
>10721
          Length = 1542

 Score =  290 bits (742), Expect = 2e-79,   Method: Compositional matrix adjust.
 Identities = 135/194 (69%), Positives = 157/194 (80%)
 Frame = -2

Query: 4    GNAKIGYPAPNFKATAVMPDGQFKDISLSEYKGKYVVFFFYPLDFTFVCPTEIIAFSDRA 63
            G   I  PAP F   AV+ DG FK + LS+YKGKYVV FFYPLDFTFVCPTEIIAFSDR 
Sbjct: 1463 GQLAIQKPAPEFSVQAVV-DGDFKTVKLSDYKGKYVVLFFYPLDFTFVCPTEIIAFSDRV 1287

Query: 64   DEFKKLNCQVIGASVDSHFCHLAWINTPKKQGGLGPMNIPLISDPKRTIAQDYGVLKADE 123
            +EF+ + C+V+ AS DS F HLAW+NTP+KQGGLG M IPL++D    +++ YG LK DE
Sbjct: 1286 EEFRSIQCEVLAASTDSVFSHLAWVNTPRKQGGLGNMKIPLLADKTLELSRMYGCLKEDE 1107

Query: 124  GISFRGLFIIDDKGILRQITINDLPVGRSVDEIIRLVQAFQFTDKHGEVCPAGWKPGSDT 183
            GI++R L+IIDDKG LRQIT+NDLPVGRSVDE +RLVQAFQFTDKHGEVCPAGWKPG+DT
Sbjct: 1106 GIAYRALYIIDDKGTLRQITMNDLPVGRSVDETLRLVQAFQFTDKHGEVCPAGWKPGADT 927

Query: 184  IKPDVNKSKEYFSK 197
            IKP V  SK +FSK
Sbjct: 926  IKPSVKDSKTFFSK 885
>09130
          Length = 1000

 Score =  283 bits (724), Expect = 3e-77,   Method: Compositional matrix adjust.
 Identities = 135/195 (69%), Positives = 158/195 (81%)
 Frame = +1

Query: 5   NAKIGYPAPNFKATAVMPDGQFKDISLSEYKGKYVVFFFYPLDFTFVCPTEIIAFSDRAD 64
            A I  PAP++  TAV+ DG+FKDI LS+++GKY+VFFFYPLDFTFVCPTEI+AFSD   
Sbjct: 190 QAVISKPAPDWNGTAVI-DGEFKDIKLSDFRGKYLVFFFYPLDFTFVCPTEIVAFSDNVG 366

Query: 65  EFKKLNCQVIGASVDSHFCHLAWINTPKKQGGLGPMNIPLISDPKRTIAQDYGVLKADEG 124
           +FK +N +V+  SVDS F HLAWINTP+ QGGLGP+ IPL+SD    IA+ YGV   D G
Sbjct: 367 KFKSINTEVVACSVDSQFTHLAWINTPRNQGGLGPLKIPLLSDITHDIAKAYGVYLQDLG 546

Query: 125 ISFRGLFIIDDKGILRQITINDLPVGRSVDEIIRLVQAFQFTDKHGEVCPAGWKPGSDTI 184
            S RGLFIID KGILRQIT+NDLPVGRSVDE +RLVQAFQ+TD HGEVCP GWKPGSDTI
Sbjct: 547 HSLRGLFIIDPKGILRQITMNDLPVGRSVDETLRLVQAFQYTDAHGEVCPVGWKPGSDTI 726

Query: 185 KPDVNKSKEYFSKQK 199
            PD  +SK+YF+KQK
Sbjct: 727 IPDPKQSKKYFNKQK 771
>09123
          Length = 1944

 Score = 75.1 bits (183), Expect = 2e-14,   Method: Compositional matrix adjust.
 Identities = 50/172 (29%), Positives = 83/172 (48%), Gaps = 12/172 (6%)
 Frame = -3

Query: 38   YVVFFFYPLDFTFVCPTEIIAFSDRADEFKKLNCQVIGASVDSHFCHLAWINTPKKQGGL 97
            + + F +P D+T VC TE+    +   EF+K  C+V   S D    H  W    +K  G+
Sbjct: 1606 WAILFSHPADYTPVCTTELGRVLNLIGEFEKRKCKVFALSCDGPESHKGWAKDVQKYAGV 1427

Query: 98   GP---MNIPLISDPKRTIAQDYGVL----KADEG--ISFRGLFIIDDKGILRQITINDLP 148
                    P+I+D KR +A   G++    K  +G  ++ R +FII     L+   +    
Sbjct: 1426 DTDTKFPYPIIADEKRDLAVQLGMVDPAEKTKDGLPLTCRAVFIIGPDKKLKLSLLYPAT 1247

Query: 149  VGRSVDEIIRLVQAFQFTDKHGEVCPAGWKPGSDT-IKPDVN--KSKEYFSK 197
             GR+ DEI+R++ + Q T       P  W+PG    + P V+  ++K+ F+K
Sbjct: 1246 TGRNFDEILRVLDSLQLTATKKVATPENWQPGGKCMVIPSVSDEEAKKLFTK 1091
>10713
          Length = 1615

 Score = 28.5 bits (62), Expect = 2.0,   Method: Compositional matrix adjust.
 Identities = 11/32 (34%), Positives = 19/32 (59%)
 Frame = -1

Query: 74   IGASVDSHFCHLAWINTPKKQGGLGPMNIPLI 105
            I   V++++CH  ++N   KQG    ++I LI
Sbjct: 1264 ISFRVETNYCHQIFLNKRLKQGSCASIHIHLI 1169
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|84490431|ref|NP_001033708.1| dynamin 3 isoform 1 [Mus
musculus]
         (863 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

29522                                                                 293   2e-79
38072                                                                  95   1e-36
13952                                                                  35   0.16 
15376                                                                  33   0.34 
33196                                                                  30   3.3  
>29522
          Length = 698

 Score =  293 bits (751), Expect = 2e-79,   Method: Compositional matrix adjust.
 Identities = 137/206 (66%), Positives = 169/206 (82%)
 Frame = -3

Query: 344 IEGSGDQVDTLELSGGAKINRIFHERFPFEIVKMEFNEKELRREISYAIKNIHGIRTGLF 403
           IEG G QV T +LSGGAKINRIFHERFPFE+VKMEF+E+ELR+EI   I+NIHGIRTGLF
Sbjct: 696 IEGFGAQVSTEDLSGGAKINRIFHERFPFELVKMEFDERELRKEIGITIRNIHGIRTGLF 517

Query: 404 TPDMAFEAIVKKQIVKLKGPSLKSVDLVMQELINTVKKCTKRLANFPRLCEETERIVANH 463
           TPDMAFE+IV KQI +LK PSL  VDLV+ EL   V+K  ++++ +PRL EETERIV + 
Sbjct: 516 TPDMAFESIVVKQIERLKEPSLHCVDLVITELSQVVRKAGEKMSRYPRLREETERIVNSR 337

Query: 464 IREREGKTKDQVLLLIDIQVSYINTNHEDFIGFANAQQRSSQVHKKSTIGNQVIRKGWLT 523
           IRE+E + K+Q+L LID Q++Y+NTNHEDFIGF+NAQQ++     K  +GNQVIRKGWL+
Sbjct: 336 IREQEQRAKEQILTLIDFQLAYMNTNHEDFIGFSNAQQKAESQSSKRKMGNQVIRKGWLS 157

Query: 524 VSNIGIMKGGSKGYWFVLTAESLSWY 549
           + NI  +KGGSK +WFVLTAESLSW+
Sbjct: 156 LHNISFIKGGSKDFWFVLTAESLSWF 79
>38072
          Length = 513

 Score = 95.1 bits (235), Expect(2) = 1e-36,   Method: Compositional matrix adjust.
 Identities = 51/84 (60%), Positives = 63/84 (75%)
 Frame = -3

Query: 607 EDVDSWKASLLRAGVYPDKSVGSNKTENDENGQAENFSMDPQLERQVETIRNLVDSYMSI 666
           EDVDSWKAS LRAGVYP++S   + +      + +  SMDPQLERQVETIRNLVDSYM I
Sbjct: 511 EDVDSWKASFLRAGVYPERSSDESSS-----SKDDYSSMDPQLERQVETIRNLVDSYMKI 347

Query: 667 INKCIRDLIPKTIMHLMINNVKDF 690
           +NK  RDLIPKTIMH+++   ++ 
Sbjct: 346 VNKTQRDLIPKTIMHIIVKKCEEL 275

 Score = 77.4 bits (189), Expect(2) = 1e-36,   Method: Compositional matrix adjust.
 Identities = 47/109 (43%), Positives = 58/109 (53%)
 Frame = -1

Query: 686 NVKDFINSELLAQLYSSEDQNTLMEESAEQAQRRDEMLRMYQALKEALAIIGDINTXXXX 745
           NVK FI S+LLA LYS+ DQ+ +MEES E+AQRRDE+LRMY A +EAL II DI+T    
Sbjct: 288 NVKSFIGSDLLAHLYSN-DQSAMMEESQEEAQRRDEILRMYHATREALTIISDISTTTVS 112

Query: 746 XXXXXXXXXXWLQHXXXXXXXXXXXXXXXXISAPLPRPTSGRGPAPAIP 794
                     WL+                        P +GR P+PA P
Sbjct: 111 TPTPPPVKDDWLEPSSGST------------------PYNGRPPSPARP 19
>13952
          Length = 577

 Score = 34.7 bits (78), Expect = 0.16,   Method: Compositional matrix adjust.
 Identities = 31/127 (24%), Positives = 60/127 (47%), Gaps = 18/127 (14%)
 Frame = -3

Query: 517 IRKGWLTVSNIGIMKGGS-----KGYWFVLTAESLSWYXXXXXXXXXYMLPLDNLKVRDV 571
           +++GWL       MK G      K  WF+L    L ++          ++PL+N++VR++
Sbjct: 419 VKEGWL-------MKQGGRYKNWKRRWFILNDNCLYYFQYTADKEPKGIIPLENIQVREL 261

Query: 572 EKGFMSSKHVFALFNTEQRNVYK------DYRFLE-------LACDSQEDVDSWKASLLR 618
            +   S  + F L++    +V K      D + +E       ++  S E++D+W +S +R
Sbjct: 260 SEK-SSRSNAFELYSVSGSDVIKACKVDSDGKVVEGRHSVYRMSASSAEEMDAWISS-IR 87

Query: 619 AGVYPDK 625
            G+  D+
Sbjct: 86  YGI*EDQ 66
>15376
          Length = 712

 Score = 33.5 bits (75), Expect = 0.34,   Method: Composition-based stats.
 Identities = 21/92 (22%), Positives = 45/92 (48%), Gaps = 13/92 (14%)
 Frame = +1

Query: 538 WFVLTAESLSWYXXXXXXXXXYMLPLDNLKVRDVEKGFMSSKHVFALFNTEQRNVYK--- 594
           WF+L    L ++          ++PL+N++VR++ +   S  + F L++    +V K   
Sbjct: 4   WFILNDNCLYYFQYTADKEPKGIIPLENIQVRELSEK-SSRSNAFELYSVSGSDVIKACK 180

Query: 595 ---DYRFLE-------LACDSQEDVDSWKASL 616
              D + +E       ++  S E++D+W +S+
Sbjct: 181 VDSDGKVVEGRHSVYRMSASSAEEMDAWISSI 276
>33196
          Length = 373

 Score = 30.4 bits (67), Expect = 3.3,   Method: Composition-based stats.
 Identities = 17/51 (33%), Positives = 26/51 (50%), Gaps = 2/51 (3%)
 Frame = -3

Query: 605 SQEDVDSWKASLLRAGVYPDKSVGSNKTE--NDENGQAENFSMDPQLERQV 653
           S    ++W+ +L +   YPD  +GSN+ E   DE  +   F  DP L R +
Sbjct: 338 SGRKFETWRTTLEK---YPDTLLGSNEKEFFYDEESKEYFFDRDPDLFRHI 195
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6756037|ref|NP_035868.1| tyrosine
3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta
polypeptide [Mus musculus]
         (246 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

12344                                                                 290   4e-79
33715                                                                 172   8e-44
13465                                                                 170   4e-43
17028                                                                 124   5e-29
15092                                                                 119   1e-27
27988                                                                  72   1e-20
>12344
          Length = 1658

 Score =  290 bits (742), Expect = 4e-79,   Method: Compositional matrix adjust.
 Identities = 154/246 (62%), Positives = 182/246 (73%)
 Frame = +2

Query: 1   MGDREQLLQRARLAEQAERYDDMASAMKAVTELNEPLSNEDRNLLSVAYKNVVGARRSSW 60
           MGDRE  + +A+   +AERYD+M   MK V  ++  L+ E+RNLLSVAYKNV+GARR+SW
Sbjct: 56  MGDREDQVYQAKQLNRAERYDEMVKFMKIVACMDVELTVEERNLLSVAYKNVIGARRASW 235

Query: 61  RVISSIEQKTMADGNEKKLEKVKAYREKIEKELETVCNDVLALLDKFLIKNCNDFQYESK 120
           R++SS+EQK   D  E K    K YR KIEKEL+ +C DVL +L+K LI N N    ESK
Sbjct: 236 RIVSSLEQKE--DKCEDKKAINKEYRMKIEKELKDICEDVLDILEKHLIVNAN--TGESK 403

Query: 121 VFYLKMKGDYYRYLAEVASGEKKNSVVEASEAAYKEAFEISKEHMQPTHPIRLGLALNFS 180
           VFY KMKGDY+RYLAE A G  +    E S  AYK A +I+   + PTHPIRLGLALNFS
Sbjct: 404 VFYYKMKGDYHRYLAEFAVGNDRKEAAENSLVAYKAASDIAMIELAPTHPIRLGLALNFS 583

Query: 181 VFYYEIQNAPEQACLLAKQAFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDQQDE 240
           VFYYEI N+P++AC LAK AFDDAIAELDTL+E+SYKDSTLIMQLLRDNLTLWTSD Q  
Sbjct: 584 VFYYEILNSPDRACRLAKAAFDDAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSDMQ-- 757

Query: 241 EAGEGN 246
             GEG 
Sbjct: 758 --GEGG 769
>33715
          Length = 434

 Score =  172 bits (437), Expect = 8e-44,   Method: Compositional matrix adjust.
 Identities = 85/123 (69%), Positives = 99/123 (80%)
 Frame = -1

Query: 124 LKMKGDYYRYLAEVASGEKKNSVVEASEAAYKEAFEISKEHMQPTHPIRLGLALNFSVFY 183
           LKMKGDYYRYL+EV+ GE++   V  S  AYKEA +++KE +  THPIRLGLALNFSVF+
Sbjct: 374 LKMKGDYYRYLSEVSQGEQRKENVGKSMEAYKEATDMAKERLSSTHPIRLGLALNFSVFH 195

Query: 184 YEIQNAPEQACLLAKQAFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDQQDEEAG 243
           YEI+N P++AC LAK AFD+AI  LD LNE+SYKDSTLIMQLLRDNLTLWTSD Q    G
Sbjct: 194 YEIKNCPDEACRLAKIAFDEAIQCLDQLNEESYKDSTLIMQLLRDNLTLWTSDSQ----G 27

Query: 244 EGN 246
           EG 
Sbjct: 26  EGT 18
>13465
          Length = 596

 Score =  170 bits (431), Expect = 4e-43,   Method: Compositional matrix adjust.
 Identities = 84/155 (54%), Positives = 111/155 (71%)
 Frame = +2

Query: 1   MGDREQLLQRARLAEQAERYDDMASAMKAVTELNEPLSNEDRNLLSVAYKNVVGARRSSW 60
           M DR+  + +A+LAEQAERYD+M  AMK V  +   L+ E+RNLLSVAYKNV+GARR+SW
Sbjct: 110 MTDRDDFVYQAKLAEQAERYDEMVEAMKKVASMGNDLTVEERNLLSVAYKNVIGARRASW 289

Query: 61  RVISSIEQKTMADGNEKKLEKVKAYREKIEKELETVCNDVLALLDKFLIKNCNDFQYESK 120
           R++SS+EQK +   +  K +  K YR++IE EL+ +C DVL ++D  LI +    Q ESK
Sbjct: 290 RIVSSVEQKDLDKPDPDKGKMTKGYRQQIETELKQICEDVLKIIDDHLIPSTT--QGESK 463

Query: 121 VFYLKMKGDYYRYLAEVASGEKKNSVVEASEAAYK 155
           VFY KMKGDYYRYLAE A+G+ +    E+S  AYK
Sbjct: 464 VFYYKMKGDYYRYLAEFATGDPRKEAAESSLVAYK 568
>17028
          Length = 1078

 Score =  124 bits (310), Expect = 5e-29,   Method: Compositional matrix adjust.
 Identities = 61/96 (63%), Positives = 73/96 (76%), Gaps = 1/96 (1%)
 Frame = +1

Query: 146 VVEASEAAYKEAFEISKEHMQPTHPIRLGLALNFSVFYYEIQNAPEQACLLAKQAFDDAI 205
            V  ++ AY +A E++K+ M PTHP RLGLALN+SVFYYEI N+ ++AC LAK AFD+AI
Sbjct: 34  AVTKAQEAYNKAMEVAKQSMAPTHPNRLGLALNYSVFYYEILNSQDKACDLAKTAFDEAI 213

Query: 206 AELDTLNE-DSYKDSTLIMQLLRDNLTLWTSDQQDE 240
            E+D   E D  KDSTLIMQLLRDNLTLWTSD   E
Sbjct: 214 QEMDQCGERDDCKDSTLIMQLLRDNLTLWTSDSNAE 321
>15092
          Length = 692

 Score =  119 bits (298), Expect = 1e-27,   Method: Compositional matrix adjust.
 Identities = 65/115 (56%), Positives = 82/115 (71%), Gaps = 8/115 (6%)
 Frame = +3

Query: 1   MGDREQLLQRARLAEQAERYDDMASAM-KAVTE-------LNEPLSNEDRNLLSVAYKNV 52
           +  +E+ +  A++AEQAERYDDMA +M K V E        +  L NE+RNLLSVAYKNV
Sbjct: 222 LSPKERQVHAAKIAEQAERYDDMAESMHKCVVEGYSANGDKSSTLDNEERNLLSVAYKNV 401

Query: 53  VGARRSSWRVISSIEQKTMADGNEKKLEKVKAYREKIEKELETVCNDVLALLDKF 107
           VGARRS+WRVISSIEQKT  + N+KKLE  K YREK+EKEL+ +C  VL  +  +
Sbjct: 402 VGARRSAWRVISSIEQKT--ENNDKKLEMAKKYREKVEKELKEICTQVLVRIHHY 560
>27988
          Length = 448

 Score = 72.0 bits (175), Expect(2) = 1e-20,   Method: Compositional matrix adjust.
 Identities = 38/60 (63%), Positives = 46/60 (76%)
 Frame = +3

Query: 44  LLSVAYKNVVGARRSSWRVISSIEQKTMADGNEKKLEKVKAYREKIEKELETVCNDVLAL 103
           L SVAYKNVVGARRSSWRVI  IEQK  A+   +K EK +A+R+ +EKEL+  CN+VL L
Sbjct: 276 LFSVAYKNVVGARRSSWRVICMIEQK--AETQPRK-EKARAFRKDVEKELDATCNEVLKL 446

 Score = 45.1 bits (105), Expect(2) = 1e-20,   Method: Compositional matrix adjust.
 Identities = 23/36 (63%), Positives = 27/36 (75%)
 Frame = +2

Query: 7   LLQRARLAEQAERYDDMASAMKAVTELNEPLSNEDR 42
           L+  A+LAEQAERYDDMA AMK VTE ++ L  E R
Sbjct: 164 LISFAKLAEQAERYDDMAKAMKKVTENDKTLMQESR 271
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|56605992|ref|NP_114397.3| sarcolemma associated
protein [Mus musculus]
         (821 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

14682                                                                 266   7e-79
14883                                                                  40   0.005
08467                                                                  31   2.2  
15691                                                                  29   6.1  
11088                                                                  29   6.1  
06178                                                                  29   9.2  
08946                                                                  29   9.4  
>14682
          Length = 1076

 Score =  266 bits (680), Expect(2) = 7e-79,   Method: Compositional matrix adjust.
 Identities = 137/236 (58%), Positives = 181/236 (76%), Gaps = 3/236 (1%)
 Frame = -1

Query: 90   EESPPCEILSGDIIQFGVDVTENTR---KVTHGCIVSTIKLFLPDGMEARLRSDVIHAPL 146
            EESP  E+ SGD+IQFGV+V EN R   K+THGCI++T+ L+ PDG EA+        P+
Sbjct: 1076 EESPMREVYSGDLIQFGVEVMENNRRGEKITHGCIIATLTLYHPDGREAK--------PV 921

Query: 147  PSPVDKVAANTPSMYSQELFQLSQYLQEALHREQMLEQKLATLQRLLAITQEASDTSWQA 206
            P   D     T ++ SQ+L+QL+ +LQEALHRE+MLEQKL +LQ+L+  TQEA++  WQA
Sbjct: 920  PFLSDPNQPGT-TIQSQDLYQLAHFLQEALHREKMLEQKLGSLQQLVHXTQEAAEGGWQA 744

Query: 207  LIDEDRLLSRLEVMGNQLQACSKNQTEDSLRKELIALQEDKHSYETTAKESLRRVLQEKI 266
            LIDED+LLSRLE++ NQL   SKN +EDSLR+EL+ALQEDK +YETTAKESLRRVLQEK+
Sbjct: 743  LIDEDKLLSRLEMLENQLHIYSKNHSEDSLRQELVALQEDKINYETTAKESLRRVLQEKL 564

Query: 267  EVVRKLSEVERSLSNTEDECTHLKEMNERTQEELRELANKYNGAVNEIKDLSDKLK 322
            + V KLS++ERSL++ E EC HLKEM E +QEEL++LA +Y   + E+ +L +KL+
Sbjct: 563  DAVTKLSDLERSLTSAEGECNHLKEMCESSQEELKQLATRYQDQLKEVMELQEKLQ 396

 Score = 47.4 bits (111), Expect(2) = 7e-79,   Method: Compositional matrix adjust.
 Identities = 25/61 (40%), Positives = 41/61 (67%)
 Frame = -3

Query: 342 LQTKIDEMEEKEQELQAKIEALQADNDFTNERLTALQVRLEHLQEKTLKECSSLGIQVDD 401
           L  K+++M ++E  L AKIE+LQADNDF  E+L A++ +LE  +E   +E  +L + ++D
Sbjct: 339 LMEKLEDMIQQESSLSAKIESLQADNDFAREQLAAMKAKLESKKETNQEEDKALDLGLED 160

Query: 402 F 402
            
Sbjct: 159 I 157
>14883
          Length = 954

 Score = 39.7 bits (91), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 19/37 (51%), Positives = 28/37 (75%)
 Frame = -3

Query: 342 LQTKIDEMEEKEQELQAKIEALQADNDFTNERLTALQ 378
           L  K+++M ++E  L AKIE+LQADNDF  E+L A++
Sbjct: 856 LMEKLEDMIQQESSLSAKIESLQADNDFAREQLAAMK 746
>08467
          Length = 1621

 Score = 30.8 bits (68), Expect = 2.2,   Method: Compositional matrix adjust.
 Identities = 14/48 (29%), Positives = 25/48 (52%)
 Frame = -3

Query: 219 VMGNQLQACSKNQTEDSLRKELIALQEDKHSYETTAKESLRRVLQEKI 266
           V+ N  +   + +T   +   +  L + KHSYE TA + LR  +Q ++
Sbjct: 902 VINNLQEGIKRMRTRTHVHTHITLLFKPKHSYEATANQPLRYFVQSRL 759
>15691
          Length = 587

 Score = 29.3 bits (64), Expect = 6.1,   Method: Compositional matrix adjust.
 Identities = 25/64 (39%), Positives = 35/64 (54%)
 Frame = +3

Query: 564 TEISSTRDKLLSAQDEILLLRQAAAEAVSERDTDFVSLQEELKKVRAELEGWRKAASEYE 623
           TEI   RD+L   Q  I  L    A   +ERD   +S+Q  L +++ ELE  R  +S+ E
Sbjct: 339 TEIKRLRDQLAERQSRIAELEAQLASMKAERDN--MSMQ--LSELQQELEKLRIDSSKKE 506

Query: 624 NEIR 627
           NE+R
Sbjct: 507 NELR 518
>11088
          Length = 1298

 Score = 29.3 bits (64), Expect = 6.1,   Method: Compositional matrix adjust.
 Identities = 45/147 (30%), Positives = 71/147 (48%), Gaps = 7/147 (4%)
 Frame = -3

Query: 663  DVLETECHSLKKENVLLSSELQRQEKELHNSQKQSFELTSDLSILQMTRKELEKQVGSLK 722
            + L  E H+LKKE   L+   +++E+ L N      +L+  L  L+  + ELE+ +   K
Sbjct: 1035 NTLLKEIHALKKEKERLAMNYEQEEEYLTN------DLSRKLFKLRQEKIELEETLE--K 880

Query: 723  EQHLRDAADLKTLLSKAENQAKDVQKEYEKTQTVLSELKLKFEMT---EQEKQSITDELK 779
            EQ     A +  L+ K E    D    Y K QT+    + K E+    EQE++S+ + L 
Sbjct: 879  EQE----AQINKLMRKIEKLEADT---YSKQQTLEQLRREKVELENALEQEQESLVNRLW 721

Query: 780  QCKDNL----KLLREKGNNPSILQPVP 802
            +  D L    +LL+EK + P    P P
Sbjct: 720  KRMDKLEAEKRLLQEKLDQPVSAPPSP 640
>06178
          Length = 1026

 Score = 28.9 bits (63), Expect = 9.2,   Method: Compositional matrix adjust.
 Identities = 19/40 (47%), Positives = 22/40 (55%), Gaps = 8/40 (20%)
 Frame = -1

Query: 787 LLREKGNNPSILQPVPAVFIGLF----LAFLFW----CFG 818
           +L EK NNP ++  V  VFI LF    L  LFW    CFG
Sbjct: 798 ILTEKKNNPQVIFEVEGVFIFLFCLIDLLVLFWAYPECFG 679
>08946
          Length = 521

 Score = 28.9 bits (63), Expect = 9.4,   Method: Compositional matrix adjust.
 Identities = 23/78 (29%), Positives = 42/78 (53%), Gaps = 5/78 (6%)
 Frame = +2

Query: 428 SKLSKENQAKAKESDLSDTLSPSKEKSSDDTTDAQ-MDEQDLNEPLAKVSLLKDDLQGTQ 486
           ++ S+E+QA+    DLS+ +SP  +  S   +  Q + +QDL +P A  SL +    G+ 
Sbjct: 275 AQASQESQAEGGALDLSNKMSPPAQPFSPPRSPVQDLPQQDLLQPSAPDSLKRSHTDGST 454

Query: 487 SETE----AKQDIQHLRK 500
           + +E      +DIQ  ++
Sbjct: 455 NSSEDNMCVAEDIQPRKR 508
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|26986637|ref|NP_758514.1| threonyl-tRNA
synthetase-like 2 [Mus musculus]
         (790 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

07414                                                                 291   8e-79
19083                                                                 222   4e-58
12449                                                                  59   7e-09
06461                                                                  40   0.004
>07414
          Length = 787

 Score =  291 bits (744), Expect = 8e-79,   Method: Compositional matrix adjust.
 Identities = 138/219 (63%), Positives = 168/219 (76%)
 Frame = -2

Query: 572 FLGEIEIWDEAERQLQNSLVEFGKPWKINPGDGAFYGPKIDIKIKDAIGRYHQCATIQLD 631
           FLGEI +WD AE+QL   L E G  +++NPGDGAFYGPKIDI IKDA+ R HQCATIQLD
Sbjct: 783 FLGEISVWDSAEQQLSEVLEESGLKFELNPGDGAFYGPKIDITIKDALRRSHQCATIQLD 604

Query: 632 FQLPIRFNLTYVSKDGDDKNRPVIIHRAILGSVERMIAILSENYGGKWPLWLSPRQVMVI 691
           FQLP RF LTY++  G+ + RPVI+HRA+LGSVERM+AIL EN+GGKWP WLSPRQ +V+
Sbjct: 603 FQLPERFGLTYINDHGE-RLRPVIVHRAVLGSVERMMAILCENFGGKWPFWLSPRQSIVV 427

Query: 692 PVGPACENYALQVSKECFEEGFMADVDLDDSCTLNKKIRNAQLAQYNFILVVGEKEKINN 751
           PV P  + YA +V K+  + GF+ D DLD   T+NKKIRNAQLAQYNFI VVGEKE  N 
Sbjct: 426 PVAPPFDEYADKVKKQIHDAGFLCDHDLDTGTTMNKKIRNAQLAQYNFIFVVGEKELANG 247

Query: 752 AVNVRTRDNKIHGEISIASVIEKLKNLKKSRTLNAEEDF 790
            VNVRTRDNK+HGE S+  VI++  + K +   +AE+ F
Sbjct: 246 TVNVRTRDNKVHGEHSVEHVIQRFSHFKTAFVQDAEDTF 130
>19083
          Length = 459

 Score =  222 bits (566), Expect = 4e-58,   Method: Compositional matrix adjust.
 Identities = 105/152 (69%), Positives = 120/152 (78%)
 Frame = -3

Query: 569 PEHFLGEIEIWDEAERQLQNSLVEFGKPWKINPGDGAFYGPKIDIKIKDAIGRYHQCATI 628
           P+ +LGE+E W+ AE+ L  SL EFG PWK NPGDGAFYGPKIDI I DA+ R  QCATI
Sbjct: 454 PDKYLGELEQWNAAEKALAESLNEFGMPWKENPGDGAFYGPKIDITIMDALKRPFQCATI 275

Query: 629 QLDFQLPIRFNLTYVSKDGDDKNRPVIIHRAILGSVERMIAILSENYGGKWPLWLSPRQV 688
           QLDFQLPIRFNL Y++ DG +K RPVIIHRAILGSVERMIAIL+ENY GKWP WLSPRQV
Sbjct: 274 QLDFQLPIRFNLNYIADDG-EKKRPVIIHRAILGSVERMIAILTENYAGKWPFWLSPRQV 98

Query: 689 MVIPVGPACENYALQVSKECFEEGFMADVDLD 720
           MV+PVGPA + YA  V  +    GFM++ D D
Sbjct: 97  MVVPVGPAYDEYAKSVRDQLHAAGFMSESDCD 2
>12449
          Length = 600

 Score = 58.9 bits (141), Expect = 7e-09,   Method: Compositional matrix adjust.
 Identities = 42/134 (31%), Positives = 64/134 (47%), Gaps = 12/134 (8%)
 Frame = -3

Query: 167 TTPYQVAAGISKELAEHTVIAKVNGVLWDLDRPLEGDSTVELLMFDNEE---AQAVYWHS 223
           +TP+  A  I + L   + +A VNG  WD+ RPL     +E + F++ +   A   +W S
Sbjct: 415 STPFHCAMHIQELLMSRSALALVNGEPWDMHRPLTDSCELEFMHFEDPDPTPANEAFWRS 236

Query: 224 SAHILGEAMELYYGGH----LCY--GPPIENG-FYY--DMFIEDRVVSSTELSALENICK 274
            + ILG  +E  +  H    LC    P + +G F Y  D+ + D   S+ EL  L     
Sbjct: 235 CSFILGYVLENAFKDHHYVELCSFPKPNVHSGSFVYDVDLRLGDWKPSAKELDILGRTGF 56

Query: 275 TIIKEKQPFERLEV 288
            +     PFERL+V
Sbjct: 55  KLFFNNYPFERLDV 14
>06461
          Length = 1131

 Score = 39.7 bits (91), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 36/122 (29%), Positives = 55/122 (45%), Gaps = 13/122 (10%)
 Frame = -3

Query: 638 FNLTYVSKDGDDKNRPVIIHRAILG-SVERM----IAILSENYGGKWPLWLSPRQVMVIP 692
           FN TY+    DD      IH    G  V R+    + +LS     +WP  ++P QV +IP
Sbjct: 679 FNATYM----DDSESIKPIHMGCFGLGVTRILQATVEVLSRERQLRWPPLMAPYQVCIIP 512

Query: 693 -----VGPACENYALQVSKE-CFEEGFMADVDLDDSC--TLNKKIRNAQLAQYNFILVVG 744
                   AC   A ++S   C       +V +DD    ++ ++I  A    Y +I+VVG
Sbjct: 511 QKEGYQADACFRLAEELSDALCSLPHLAGEVLIDDRIKFSIGRRIYEASRLGYPYIIVVG 332

Query: 745 EK 746
           +K
Sbjct: 331 KK 326
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|51592084|ref|NP_067389.3| S-adenosylhomocysteine
hydrolase-like 2 [Mus musculus]
         (613 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

18254                                                                 291   8e-79
18314                                                                 234   9e-62
07987                                                                 104   1e-22
25186                                                                  52   6e-07
01696                                                                  31   1.5  
>18254
          Length = 928

 Score =  291 bits (744), Expect = 8e-79,   Method: Compositional matrix adjust.
 Identities = 148/297 (49%), Positives = 203/297 (68%), Gaps = 2/297 (0%)
 Frame = +3

Query: 301 VEGWQP-NMILDDGGDLTHWIYKKYPNMFKKIKGIVEESVTGVHRLYQLSKAGKLCVPAM 359
           V+  QP NMILDDGGDLT+ +++KYP     IKG+ EE+ TGVH LY++    KL VPA+
Sbjct: 36  VQNGQPLNMILDDGGDLTNLVHEKYPQYLAGIKGLSEETTTGVHNLYRMMAEKKLKVPAI 215

Query: 360 NVNDSVTKQKFDNLYCCRESILDGLKRTTDMMFGGKQVVVCGYGEVGKGCCAALKAMGSI 419
           NVNDSVTK KFDNLY CRES++DG+KR TD+M  GK  VV GYG+VGKGC  AL+A G+ 
Sbjct: 216 NVNDSVTKSKFDNLYGCRESLVDGIKRATDVMLAGKVAVVAGYGDVGKGCAQALRAFGAR 395

Query: 420 VYVTEIDPICALQACMDGFRLVKLNEVIRQVDIVITCTGNKNVVTREHLDRMKNSCIVCN 479
           V +TEIDPI ALQA M+G+ +  +++ + +  I +T TG K ++  +H + M    I+CN
Sbjct: 396 VIITEIDPINALQAAMEGYEVSTIDDSLSEARIFVTATGCKGILRPKHFENMLEDTIICN 575

Query: 480 MGHSNTEIDVASLRTPELTWERVRSQVDHVIWPDGKRIVLLAEGRLLNLSCS-TVPTFVL 538
           +GH + EID+A L     + E V+ QV+      G+ +++LAEGRL+NL C+   P+FV+
Sbjct: 576 IGHFDCEIDIAWLNDNCRSKEVVQPQVERYTMKSGRHLIVLAEGRLVNLGCAHGHPSFVM 755

Query: 539 SITATTQALALIELYNAPEGRYKQDVYLLPKKMDEYVASLHLPTFDAHLTELTDEQA 595
           S + T Q LA IEL+     +Y   V++LPKK+DE VA+LHL      LT+L D+QA
Sbjct: 756 SNSFTNQVLAQIELWTKTS-QYVLGVHMLPKKLDEEVAALHLSHLGVKLTKLDDDQA 923
>18314
          Length = 475

 Score =  234 bits (596), Expect = 9e-62,   Method: Compositional matrix adjust.
 Identities = 110/148 (74%), Positives = 124/148 (83%)
 Frame = -3

Query: 176 DKQQKNSKGSSDFCVKNIKQAEFGRREIEIAEQEMPALMALRKRAQGEKPLAGAKIVGCT 235
           +   +  +GS  F  +NI+   FGRREIEIAEQEMP LMALRKRA+G+KPL GAKI+GCT
Sbjct: 446 ETSNRKLQGSW*FLRQNIEHNAFGRREIEIAEQEMPGLMALRKRAEGDKPLHGAKIIGCT 267

Query: 236 HITAQTAVLMETLGALGAQCRWAACNIYSTLNEVAAALAESGFPVFAWKGESEDDFWWCI 295
           HITAQTAVL+ETL ALGA  RWAACNIYST NEVAAALAESG  +FAWKGE+E+DFWWCI
Sbjct: 266 HITAQTAVLVETLVALGATVRWAACNIYSTQNEVAAALAESGICIFAWKGETEEDFWWCI 87

Query: 296 DRCVNVEGWQPNMILDDGGDLTHWIYKK 323
           DRC+N EGWQPNMILDDGGD TH + KK
Sbjct: 86  DRCINAEGWQPNMILDDGGDATHLMLKK 3
>07987
          Length = 1227

 Score =  104 bits (259), Expect = 1e-22,   Method: Compositional matrix adjust.
 Identities = 60/137 (43%), Positives = 85/137 (62%), Gaps = 8/137 (5%)
 Frame = -2

Query: 485  TEIDVASLRTPELTWER-------VRSQVDHVIWPDGKRIVLLAEGRLLNLSCST-VPTF 536
            T + V + R  +LTW         V+ QV+      G+ +++LAEGRL+NL C+   P+F
Sbjct: 1187 TALSVHNYRH-DLTWRPRSI*PVVVQPQVERYTMKSGRHLIVLAEGRLVNLGCAHGHPSF 1011

Query: 537  VLSITATTQALALIELYNAPEGRYKQDVYLLPKKMDEYVASLHLPTFDAHLTELTDEQAK 596
            V+S + T Q LA IEL+     +Y   V++LPKK+DE VA+LHL      LT+L D+QA 
Sbjct: 1010 VMSNSFTNQVLAQIELWTK-TSQYVLGVHMLPKKLDEEVAALHLSHLGVKLTKLDDDQAT 834

Query: 597  YLGLNKNGPFKPNYYRY 613
            YLG+   GPFKP++YRY
Sbjct: 833  YLGIPAAGPFKPDHYRY 783
>25186
          Length = 1389

 Score = 52.0 bits (123), Expect = 6e-07,   Method: Compositional matrix adjust.
 Identities = 23/25 (92%), Positives = 25/25 (100%)
 Frame = +3

Query: 547 LALIELYNAPEGRYKQDVYLLPKKM 571
           LALIEL+NAP+GRYKQDVYLLPKKM
Sbjct: 3   LALIELFNAPQGRYKQDVYLLPKKM 77
>01696
          Length = 1636

 Score = 30.8 bits (68), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 17/34 (50%), Positives = 22/34 (64%), Gaps = 1/34 (2%)
 Frame = -1

Query: 394  GKQVVVCGYGEVGKGCCAALKAMG-SIVYVTEID 426
            GK+V+VCG G +G     + KAMG S V VT+I 
Sbjct: 1408 GKKVLVCGSGPIGLSAIVSAKAMGASDVIVTDIS 1307
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|13385374|ref|NP_080163.1| RAB5A, member RAS oncogene
family [Mus musculus]
         (215 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

33374                                                                 224   1e-78
08428                                                                 188   1e-48
01095                                                                 164   2e-41
34468                                                                 128   2e-30
26083                                                                 127   3e-30
14456                                                                 118   2e-27
29380                                                                 108   2e-24
17511                                                                 108   2e-24
07580                                                                  87   4e-22
33794                                                                  99   1e-21
07465                                                                  98   3e-21
05468                                                                  92   2e-19
01972                                                                  77   6e-19
14119                                                                  87   5e-18
13750                                                                  87   7e-18
33380                                                                  86   9e-18
11257                                                                  86   1e-17
26536                                                                  84   4e-17
25618                                                                  82   2e-16
35581                                                                  80   7e-16
30760                                                                  80   8e-16
13901                                                                  80   8e-16
32723                                                                  79   1e-15
01398                                                                  79   2e-15
19006                                                                  78   3e-15
09204                                                                  73   8e-14
34359                                                                  73   1e-13
12339                                                                  72   2e-13
13745                                                                  71   4e-13
11728                                                                  63   9e-11
00858                                                                  61   4e-10
27191                                                                  57   5e-09
10708                                                                  37   3e-08
34597                                                                  54   3e-08
14775                                                                  54   6e-08
19656                                                                  52   1e-07
31291                                                                  50   8e-07
00552                                                                  48   3e-06
08153                                                                  45   2e-05
09827                                                                  43   1e-04
10862                                                                  41   3e-04
18509                                                                  35   0.028
06994                                                                  34   0.039
33605                                                                  32   0.21 
34156                                                                  30   0.60 
30516                                                                  28   3.0  
11203                                                                  28   3.3  
19310                                                                  25   4.6  
>33374
          Length = 489

 Score =  224 bits (570), Expect(2) = 1e-78,   Method: Compositional matrix adjust.
 Identities = 103/119 (86%), Positives = 115/119 (96%)
 Frame = +1

Query: 55  AAFLTQTVCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNEESFARAKNW 114
           + FLTQTVCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITN+++F RAK W
Sbjct: 133 SCFLTQTVCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNQDTFGRAKTW 312

Query: 115 VKELQRQASPNIVIALSGNKADLANKRAVDFQEAQSYADDNSLLFMETSAKTSMNVNEI 173
           VKELQRQASPNIVIAL+GNKADLANKR V+F+EAQ+YA++NSLLFMETSAKT+MNVN+I
Sbjct: 313 VKELQRQASPNIVIALAGNKADLANKRMVEFEEAQAYAEENSLLFMETSAKTAMNVNDI 489

 Score = 86.7 bits (213), Expect(2) = 1e-78,   Method: Compositional matrix adjust.
 Identities = 43/48 (89%), Positives = 44/48 (91%)
 Frame = +2

Query: 10 NGPNTGNKICQFKLVLLGESAVGKSSLVLRFVKGQFHEFQESTIGAAF 57
          NG   G KICQFKLVLLGESAVGKSSLVLRFVKGQFHE+QESTIGAAF
Sbjct: 2  NGATQG-KICQFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAF 142
>08428
          Length = 1109

 Score =  188 bits (478), Expect = 1e-48,   Method: Compositional matrix adjust.
 Identities = 87/168 (51%), Positives = 123/168 (73%)
 Frame = -3

Query: 22   KLVLLGESAVGKSSLVLRFVKGQFHEFQESTIGAAFLTQTVCLDDTTVKFEIWDTAGQER 81
            K+ LLG+S VGKSS+VLRFV G +   QESTIGA+F+++++ +D    +F+IWDTAGQE+
Sbjct: 1065 KVCLLGDSGVGKSSIVLRFVTGSYRPSQESTIGASFMSKSLVVDGAGYRFQIWDTAGQEK 886

Query: 82   YHSLAPMYYRGAQAAIVVYDITNEESFARAKNWVKELQRQASPNIVIALSGNKADLANKR 141
            + +LAPMYYRGA AA++VYD+T   +F   K+W++EL+    PNIV+A++GNK DL   R
Sbjct: 885  FRALAPMYYRGAAAAVIVYDVTRPRTFKSVKSWIQELRSFGPPNIVLAIAGNKCDLEELR 706

Query: 142  AVDFQEAQSYADDNSLLFMETSAKTSMNVNEIFMAIAKKLPKNEPQNP 189
             V  ++AQ YA   S +F ETSA T++NV E+F  +A++LP  E  NP
Sbjct: 705  EVVEKDAQEYASSISAIFGETSAMTAVNVEEMFTELARQLPPEE-DNP 565
>01095
          Length = 1745

 Score =  164 bits (416), Expect = 2e-41,   Method: Compositional matrix adjust.
 Identities = 82/117 (70%), Positives = 98/117 (83%), Gaps = 1/117 (0%)
 Frame = -1

Query: 98   VVYDITNEESFARAKNWVKELQRQASPNIVIALSGNKADLANKRAVDFQEAQSYADDNSL 157
            VVYDITN+++F RAK WVKELQRQASPNIVIAL+GNKADLANKR V+F+EAQ+YA++NSL
Sbjct: 1745 VVYDITNQDTFGRAKTWVKELQRQASPNIVIALAGNKADLANKRMVEFEEAQAYAEENSL 1566

Query: 158  LFMETSAKTSMNVNEIFMAIAKKLPKNEPQNPGANSARGRGVDL-TEPAQPARSQCC 213
            LFMETSAKT+MNVN+IF+AIAKKLPKNE    G +  R +GV L  E +Q +   CC
Sbjct: 1565 LFMETSAKTAMNVNDIFLAIAKKLPKNE--GGGGSQPRQQGVRLNNEQSQQSEGGCC 1401
>34468
          Length = 1502

 Score =  128 bits (322), Expect = 2e-30,   Method: Compositional matrix adjust.
 Identities = 72/194 (37%), Positives = 110/194 (56%), Gaps = 5/194 (2%)
 Frame = +1

Query: 2   ANRGATRPNGPNTGNKICQFKLVLLGESAVGKSSLVLRFVKGQFHEFQESTIGAAFLTQT 61
           A  GA +     T  +I  FK++++G+S VGK+ L  RF  G+F +  E+TIG  F  ++
Sbjct: 445 AEAGAMKVVEKQTQRRI--FKIIVIGDSNVGKTCLTYRFCLGKFPDKTEATIGVDFREKS 618

Query: 62  VCLDDTTVKFEIWDTAGQERYH-SLAPMYYRGAQAAIVVYDITNEESFARAKNWVKELQR 120
           + +D   +K ++WDTAGQER+  S+   YYR   A + VYD+T   SF     W++E  R
Sbjct: 619 IQVDSEHLKLQLWDTAGQERFRKSMVQHYYRNVHAVVFVYDMTKMSSFENMPAWIEECDR 798

Query: 121 Q-ASPNIVIALSGNKADLANKRAVDFQEAQSYADDNSLLFMETSAK---TSMNVNEIFMA 176
              +  I   L GNK D+  + AV+   AQ +AD +++   ETSAK    + +V+ IFM 
Sbjct: 799 HNLTKYIPRILVGNKCDVVERIAVNTNLAQKFADAHNMPLFETSAKDDEKANHVDAIFMT 978

Query: 177 IAKKLPKNEPQNPG 190
           +A KL  ++P  P 
Sbjct: 979 VAHKLKXSKPMMPA 1020
>26083
          Length = 432

 Score =  127 bits (319), Expect = 3e-30,   Method: Compositional matrix adjust.
 Identities = 55/120 (45%), Positives = 83/120 (69%)
 Frame = +1

Query: 15  GNKICQFKLVLLGESAVGKSSLVLRFVKGQFHEFQESTIGAAFLTQTVCLDDTTVKFEIW 74
           GN + +FKLV LGE +VGK+SL+ RF+   F    ++TIG  FL++T+ L+D T++ ++W
Sbjct: 61  GNPLRKFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTIRLQLW 240

Query: 75  DTAGQERYHSLAPMYYRGAQAAIVVYDITNEESFARAKNWVKELQRQASPNIVIALSGNK 134
           DTAGQER+ SL P Y R +  A+VVYDITN  SF +   W+ +++ +   +++I L GNK
Sbjct: 241 DTAGQERFRSLIPSYIRDSSVAVVVYDITNANSFHQTSKWIDDVRTERGSDVIIMLVGNK 420
>14456
          Length = 1867

 Score =  118 bits (295), Expect = 2e-27,   Method: Compositional matrix adjust.
 Identities = 73/196 (37%), Positives = 105/196 (53%), Gaps = 8/196 (4%)
 Frame = -1

Query: 26   LGESAVGKSSLVLRFVKGQFHEFQESTIGAAFLTQTVCLDDTTVKFEIWDTAGQERYHSL 85
            L +  VGKSSL+ RFV  +F      TIG  FL + V +DD T   +IWDTAGQER+ SL
Sbjct: 1123 LKQGGVGKSSLMNRFVSNKFDAQSFHTIGVEFLNKDVVVDDETYTMQIWDTAGQERFKSL 944

Query: 86   APMYYRGAQAAIVVYDITNEESFARAKNWVKELQRQAS-------PNIVIALSGNKADLA 138
               +YRGA   ++ + + + +SF     W KE    A        P +V+   GNK D+ 
Sbjct: 943  RTPFYRGADCCLLTFSVDSMQSFRNLSMWRKEFLYYADIQDGVTFPFVVL---GNKIDVE 773

Query: 139  NKRAVDFQEAQSYADDNS-LLFMETSAKTSMNVNEIFMAIAKKLPKNEPQNPGANSARGR 197
             ++  + +EA+S+   NS   + ETSAK + NV + F+A  ++L + E Q     +A G 
Sbjct: 772  GRQVTN-EEARSWCTANSNAPYFETSAKDATNVEKAFLAAVQRLREVEDQQE-VKTAHGN 599

Query: 198  GVDLTEPAQPARSQCC 213
             VDL   A+   S CC
Sbjct: 598  TVDLNRAARGKSSSCC 551
>29380
          Length = 853

 Score =  108 bits (269), Expect = 2e-24,   Method: Compositional matrix adjust.
 Identities = 58/122 (47%), Positives = 83/122 (68%), Gaps = 2/122 (1%)
 Frame = -2

Query: 93  AQAAIVVYDITNEESFARAKNWVKELQRQASPNIVIALSGNKADLANK-RAVDFQEAQSY 151
           A AAI+VYD+   ++F+RA  WVKEL++Q + +++I L+GNK DLA + RAV F++AQS+
Sbjct: 852 ASAAIIVYDVNIADTFSRALAWVKELRQQNTESVLIILAGNKVDLATQHRAVSFEDAQSF 673

Query: 152 ADDNSLLFMETSAKTSMNVNEIFMAIAKKLPKNEPQNPGANSARGRGVDLT-EPAQPARS 210
           A +N LLF E SAKT M VNEIFM +A +L + E      + +R RGV L  E  + +  
Sbjct: 672 ARENGLLFAEVSAKTGMAVNEIFMTLANQLIQQEI-----DGSRNRGVTLNRENGEASGC 508

Query: 211 QC 212
           +C
Sbjct: 507 KC 502
>17511
          Length = 483

 Score =  108 bits (269), Expect = 2e-24,   Method: Compositional matrix adjust.
 Identities = 53/121 (43%), Positives = 76/121 (62%), Gaps = 4/121 (3%)
 Frame = -3

Query: 21  FKLVLLGESAVGKSSLVLRFVKGQFHEFQESTIGAAFLTQTVCLDDTTVKFEIWDTAGQE 80
            K+++LG+S VGK+SL+ ++V  +F    ++TIGA FLT+ V +DD  V  +IWDTAGQE
Sbjct: 364 LKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQIWDTAGQE 185

Query: 81  RYHSLAPMYYRGAQAAIVVYDITNEESFARAKNWVKELQRQASP----NIVIALSGNKAD 136
           R+ SL   +YRGA   ++V+D+T   +F    +W  E   QASP    N    + GNK D
Sbjct: 184 RFQSLGVAFYRGADCCVLVFDVTMPNTFRSLDSWRDEFLIQASPRDPENFPFVVIGNKID 5

Query: 137 L 137
           L
Sbjct: 4   L 2
>07580
          Length = 921

 Score = 87.4 bits (215), Expect(2) = 4e-22,   Method: Compositional matrix adjust.
 Identities = 53/159 (33%), Positives = 85/159 (53%), Gaps = 5/159 (3%)
 Frame = +3

Query: 40  FVKGQFHEFQESTIGAAFLTQTVCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVV 99
             KG F E  + TI  ++  Q V +D      EI DTAG E++ ++  +Y +  Q  ++ 
Sbjct: 120 LCKGIFVEKYDPTIEDSYRKQ-VEVDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFLLA 296

Query: 100 YDITNEESFARAKNWVKELQRQA-----SPNIVIALSGNKADLANKRAVDFQEAQSYADD 154
           Y IT + +F    N ++EL+ Q      + ++ + L GNK DL ++R V   + Q  A  
Sbjct: 297 YSITAQSTF----NDLQELREQILRVKDTDDVPMLLVGNKCDLEDERVVGKDQGQGLARS 464

Query: 155 NSLLFMETSAKTSMNVNEIFMAIAKKLPKNEPQNPGANS 193
            S  F+ETSAK  +NVNEIFM + +++ K  P+  G  +
Sbjct: 465 FSCAFLETSAKARINVNEIFMDLVRQINKKSPEQSGKRT 581

 Score = 33.9 bits (76), Expect(2) = 4e-22,   Method: Compositional matrix adjust.
 Identities = 14/26 (53%), Positives = 21/26 (80%)
 Frame = +2

Query: 20 QFKLVLLGESAVGKSSLVLRFVKGQF 45
          ++KLV+LG   VGKS+L ++FV+G F
Sbjct: 59 EYKLVVLGSGGVGKSALTVQFVQGDF 136
>33794
          Length = 779

 Score = 99.0 bits (245), Expect = 1e-21,   Method: Compositional matrix adjust.
 Identities = 51/125 (40%), Positives = 74/125 (59%)
 Frame = -1

Query: 55  AAFLTQTVCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNEESFARAKNW 114
            A+ T T+ L+   VK +IWDT+GQ R+ ++   Y RGAQ  I+VYDITN+ SF     W
Sbjct: 692 VAYKTTTILLEGKRVKLQIWDTSGQGRFCTIIRSYSRGAQGIILVYDITNKWSFDGIDRW 513

Query: 115 VKELQRQASPNIVIALSGNKADLANKRAVDFQEAQSYADDNSLLFMETSAKTSMNVNEIF 174
           +KE++  A P I   L GN+  LA KR V  ++A++YA  N++   E S     N+ E F
Sbjct: 512 LKEVEEHA-PGIPKVLVGNRLHLAYKRQVAAKQAETYASRNNMSCFEISPLCDFNIRESF 336

Query: 175 MAIAK 179
             +A+
Sbjct: 335 CELAR 321
>07465
          Length = 1103

 Score = 97.8 bits (242), Expect = 3e-21,   Method: Compositional matrix adjust.
 Identities = 50/147 (34%), Positives = 84/147 (57%)
 Frame = +3

Query: 34  SSLVLRFVKGQFHEFQESTIGAAFLTQTVCLDDTTVKFEIWDTAGQERYHSLAPMYYRGA 93
           SS++ R+ KG F +  + TIG  FL + + +    V+  +WDTAGQE + ++   YYRGA
Sbjct: 240 SSMIQRYCKGIFTKDYKKTIGVDFLERQIEVGGEDVRLMLWDTAGQEEFDAITKAYYRGA 419

Query: 94  QAAIVVYDITNEESFARAKNWVKELQRQASPNIVIALSGNKADLANKRAVDFQEAQSYAD 153
           QA ++ +   + +SF   + W ++++ +    I + +  NK DL +   V  +EA++ A 
Sbjct: 420 QACVLAFSTVDRDSFEALETWKRKVEDEVGE-IGMVIVQNKIDLIDDAVVRPEEAENLAK 596

Query: 154 DNSLLFMETSAKTSMNVNEIFMAIAKK 180
              L F  TS K +MNV+E+F  +A K
Sbjct: 597 KLRLRFYRTSVKENMNVDEVFRYLADK 677
>05468
          Length = 1558

 Score = 91.7 bits (226), Expect = 2e-19,   Method: Compositional matrix adjust.
 Identities = 58/206 (28%), Positives = 106/206 (51%), Gaps = 13/206 (6%)
 Frame = -3

Query: 21   FKLVLLGESAVGKSSLVLRFVKGQFHEFQESTIGAAFLTQTVCLD-DTTVKFEIWDTAGQ 79
            +K++++GE   GK+S++ R+V   F +   +TIG  F  + +  D DT ++ ++WD AGQ
Sbjct: 1538 YKILVIGELGTGKTSIIKRYVHQFFSQHYRATIGVDFALKVLNWDADTLIRLQLWDIAGQ 1359

Query: 80   ERYHSLAPMYYRGAQAAIVVYDITNEESFARAKNWVKELQRQ-----ASPNIVIALSGNK 134
            ER+ ++  +YY+ A  A VV+D+T   +F     W  +L  +      SP +   L  NK
Sbjct: 1358 ERFGNMTRVYYKEAVGAFVVFDVTRASTFDAVTKWKNDLDSKVQLADGSP-VPCVLLANK 1182

Query: 135  ADLANKRAV-DFQEAQSYADDNSLL-FMETSAKTSMNVNEI--FMAIAKKLPKNEPQNPG 190
             D A +  V +  +   +  +   + + ETSAK ++N++E   F+ + + L K+     G
Sbjct: 1181 CDQAKEGLVNNTSQMDEFCSEKGFIGWYETSAKENINIDEAARFL-VTRILEKDRAMQLG 1005

Query: 191  ANSARGRGVDLTEPA---QPARSQCC 213
             +      + L +P+   Q  +  CC
Sbjct: 1004 DDDRDRDRIVLDKPSSGTQERKINCC 927
>01972
          Length = 2359

 Score = 77.0 bits (188), Expect(2) = 6e-19,   Method: Compositional matrix adjust.
 Identities = 38/113 (33%), Positives = 67/113 (59%)
 Frame = +3

Query: 69  VKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNEESFARAKNWVKELQRQASPNIVI 128
           +KF +WDTAGQE++  L   YY   Q A++++D+T+  ++    NW ++L R    NI I
Sbjct: 447 LKFNVWDTAGQEKFGGLRDGYYIQGQCAVIMFDVTSRVTYKNVPNWHRDLVR-VCENIPI 623

Query: 129 ALSGNKADLANKRAVDFQEAQSYADDNSLLFMETSAKTSMNVNEIFMAIAKKL 181
            L GNK D+ +++     +A  +    +L + + SAK++ N  + F+ +A+KL
Sbjct: 624 VLCGNKVDIKDRKVK--AKAIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKL 776

 Score = 33.5 bits (75), Expect(2) = 6e-19,   Method: Compositional matrix adjust.
 Identities = 14/27 (51%), Positives = 20/27 (74%)
 Frame = +1

Query: 21  FKLVLLGESAVGKSSLVLRFVKGQFHE 47
           FKLVL+G+  VGK++ V R V G+F +
Sbjct: 304 FKLVLVGDGGVGKTTFVKRHVTGEFEK 384
>14119
          Length = 602

 Score = 87.0 bits (214), Expect = 5e-18,   Method: Compositional matrix adjust.
 Identities = 42/85 (49%), Positives = 62/85 (72%), Gaps = 1/85 (1%)
 Frame = +1

Query: 107 SFARAKNWVKELQRQASPNIVIALSGNKADLANK-RAVDFQEAQSYADDNSLLFMETSAK 165
           +F RA  WVKEL++Q + +++I L+GNKADLA++ RAV   +A+++A+DN L+F E SAK
Sbjct: 1   TFNRALAWVKELRQQNAGSVLIVLAGNKADLASEHRAVSADDARTFAEDNGLIFAEVSAK 180

Query: 166 TSMNVNEIFMAIAKKLPKNEPQNPG 190
           T M V+E+FM IA KL +   +  G
Sbjct: 181 TGMAVSEVFMTIAHKLVRRAEEGGG 255
>13750
          Length = 503

 Score = 86.7 bits (213), Expect = 7e-18,   Method: Compositional matrix adjust.
 Identities = 54/159 (33%), Positives = 78/159 (49%), Gaps = 8/159 (5%)
 Frame = -2

Query: 33  KSSLVLRFVKGQFHEFQESTIGAAFLTQTVC-------LDDTTVKFEIWDTAGQERYHSL 85
           K+ L+ R+ KG F +    TI        +C        D   V++ +WDT G E Y SL
Sbjct: 502 KTCLLRRYQKGFFMDRTMPTIAV------LCSEFNESRTDPLNVRYTLWDTGGAETYRSL 341

Query: 86  APMYYRGAQAAIVVYDITNEESFARAKN-WVKELQRQASPNIVIALSGNKADLANKRAVD 144
              ++RGAQ A++VYD+T E SF  A   W K L +   P   +   G+K DL   R + 
Sbjct: 340 WVSHFRGAQVALLVYDVTCEWSFLTATTVWRKALMKNI-PEAQVIFVGSKTDLEENRVIS 164

Query: 145 FQEAQSYADDNSLLFMETSAKTSMNVNEIFMAIAKKLPK 183
            +  Q++A      F ETS+ T  NV+ +F  IA  L +
Sbjct: 163 TERGQAFATQCGYTFFETSSVTGKNVDAVFWEIAFILAR 47
>33380
          Length = 282

 Score = 86.3 bits (212), Expect = 9e-18,   Method: Compositional matrix adjust.
 Identities = 38/82 (46%), Positives = 53/82 (64%)
 Frame = +3

Query: 61  TVCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNEESFARAKNWVKELQR 120
           TV   D  VK +IWDTAGQERY ++   YYRGA   I++YD+TNEESF   ++W  +++ 
Sbjct: 36  TVFRQDKRVKLQIWDTAGQERYRTITTAYYRGAMGFILMYDVTNEESFNAVQDWCTQIKT 215

Query: 121 QASPNIVIALSGNKADLANKRA 142
            +  N  + L GNK DL ++R 
Sbjct: 216 YSWDNAQVVLVGNKCDLEDERV 281
>11257
          Length = 1102

 Score = 85.9 bits (211), Expect = 1e-17,   Method: Compositional matrix adjust.
 Identities = 53/157 (33%), Positives = 83/157 (52%), Gaps = 5/157 (3%)
 Frame = -2

Query: 62   VCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNEESFARAKNWVKEL--- 118
            V +D  T   +IWDTAGQERY SL   +YRG    ++ + + N +S     +W  E    
Sbjct: 1047 VVVDGETFTMQIWDTAGQERYKSLRTPFYRGTDCCLLTFSVDNLKSLQSLSDWYDEFVNY 868

Query: 119  -QRQASPNIVIALSGNKADLANKRAVDFQEAQSYADDN-SLLFMETSAKTSMNVNEIFMA 176
               Q S +    + GNKAD+  +R V  ++A ++   + +L + ETSAK S+NV + F+A
Sbjct: 867  ADIQDSASFPFVIIGNKADI-EEREVSSEDAYNWCRTHGNLPYFETSAKDSLNVQQAFLA 691

Query: 177  IAKKLPKNEPQNPGANSARGRGVDLTEPAQPARSQCC 213
            + ++L + + Q       R   VDL   A+  +S CC
Sbjct: 690  VVRRLREMDEQM-DERPTRTDTVDLKRVAK-VKSSCC 586
>26536
          Length = 829

 Score = 84.0 bits (206), Expect = 4e-17,   Method: Compositional matrix adjust.
 Identities = 49/138 (35%), Positives = 73/138 (52%), Gaps = 3/138 (2%)
 Frame = +2

Query: 50  ESTIGAAFLTQTVCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNEESFA 109
           E TI    LT    + +  V +   DTAGQE Y S+   Y R     IVVY +T+  SF 
Sbjct: 71  ERTIMLLSLTTMKMMMERRVSWTFLDTAGQEEYSSMREHYTRSGDGFIVVYSVTDVTSFQ 250

Query: 110 RAK---NWVKELQRQASPNIVIALSGNKADLANKRAVDFQEAQSYADDNSLLFMETSAKT 166
            A+    W+   Q + S + V  L GNK DL + R V  +E +  AD   +L+ ETSAKT
Sbjct: 251 EAEAVFRWLTRFQDETSIHAV--LCGNKTDLTSDRKVTPEEGRKMADRLGMLYFETSAKT 424

Query: 167 SMNVNEIFMAIAKKLPKN 184
             NV++++  + + +P++
Sbjct: 425 GDNVSQVYHGLLRSIPRS 478

 Score = 36.6 bits (83), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 17/46 (36%), Positives = 27/46 (58%)
 Frame = +2

Query: 12  PNTGNKICQFKLVLLGESAVGKSSLVLRFVKGQFHEFQESTIGAAF 57
           P +G     +K+V+LG   VGKSSL +RF +  F +  + TI  ++
Sbjct: 470 PRSGT---DYKIVMLGSGGVGKSSLTIRFTQDTFLDVYDPTIEDSY 598
>25618
          Length = 475

 Score = 82.0 bits (201), Expect = 2e-16,   Method: Compositional matrix adjust.
 Identities = 45/98 (45%), Positives = 67/98 (68%), Gaps = 1/98 (1%)
 Frame = +3

Query: 116 KELQRQASPNIVIALSGNKADLANK-RAVDFQEAQSYADDNSLLFMETSAKTSMNVNEIF 174
           KEL++Q + +++I L+GNKADLA++ RAV   +A+++A+DN L+F E SAKT M V+E+F
Sbjct: 48  KELRQQNAGSVLIVLAGNKADLASEHRAVSADDARTFAEDNGLIFAEVSAKTGMAVSEVF 227

Query: 175 MAIAKKLPKNEPQNPGANSARGRGVDLTEPAQPARSQC 212
           M IA KL +   +  G+   R R V L+E A+ A   C
Sbjct: 228 MTIAHKLVRRAEEGQGSXQGRER-VRLSE-AEEASGGC 335
>35581
          Length = 364

 Score = 80.1 bits (196), Expect = 7e-16,   Method: Compositional matrix adjust.
 Identities = 45/117 (38%), Positives = 63/117 (53%), Gaps = 1/117 (0%)
 Frame = +2

Query: 10  NGPNTGNKICQFKLVLLGESAVGKSSLVLRFVKGQFHEFQESTIGAAFLTQTVCLDDTTV 69
           NG  TGN    FK VLLG++ VGK+ L+ R    +F +   +++  A L  TV L    +
Sbjct: 14  NGIRTGNDTLYFKCVLLGDAGVGKTCLLNRLATDKFLDSPLTSLTTASLLTTVTLTSGVM 193

Query: 70  -KFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNEESFARAKNWVKELQRQASPN 125
              ++WDTAGQERY SL   YYR  +A ++VYD    E   +  +W     R A P+
Sbjct: 194 ASVDLWDTAGQERYRSLTSSYYRDTKAVLIVYD---AEHKLKLTDWT---DRAAVPH 346
>30760
          Length = 596

 Score = 79.7 bits (195), Expect = 8e-16,   Method: Compositional matrix adjust.
 Identities = 53/168 (31%), Positives = 83/168 (49%), Gaps = 6/168 (3%)
 Frame = -1

Query: 22  KLVLLGESAVGKSSL--VLRFVKGQFHEFQESTIGAAFLTQTVCLDDT--TVKFEIWDTA 77
           K ++ G+S VGKSS+  V       F +    T G   L + V + D+   V+  ++D+A
Sbjct: 524 KCIVTGDSGVGKSSICQVFHSDSAHFPKNYSMTTGVEVLVKLVNIPDSRDQVELYLFDSA 345

Query: 78  GQERYHSLAPMYYRGAQAAIVVYDITNEESFARAKNWVKELQRQASPNIVI--ALSGNKA 135
           G+E +      ++      +VVYD+T+E SF+    W++ + R A PN VI   L  NK 
Sbjct: 344 GKEIFSENVTKFWDQPSVVMVVYDVTDETSFSGCVRWLERV-RAAKPNTVIPGVLVANKT 168

Query: 136 DLANKRAVDFQEAQSYADDNSLLFMETSAKTSMNVNEIFMAIAKKLPK 183
           DL  +R V  +E +  A  + L + E SAK   N +  F  +A    K
Sbjct: 167 DLDERRRVSRKEGKDLAQSHGLEYFECSAKEMQNTDTPFFCLAHAFHK 24
>13901
          Length = 962

 Score = 79.7 bits (195), Expect = 8e-16,   Method: Compositional matrix adjust.
 Identities = 35/95 (36%), Positives = 58/95 (61%), Gaps = 1/95 (1%)
 Frame = -3

Query: 21  FKLVLLGESAVGKSSLVLRFVKGQFHEFQESTIGAAFLTQTVCLDD-TTVKFEIWDTAGQ 79
           FK++++G+  VGK+S V R+V   F    + TIG  F  + +   D   +K ++WD AGQ
Sbjct: 285 FKVIIIGDPTVGKTSFVQRYVNDSFRRDYKMTIGVDFALKVIRWSDKCNIKLQLWDIAGQ 106

Query: 80  ERYHSLAPMYYRGAQAAIVVYDITNEESFARAKNW 114
           ER+ S+  +YY+ A A IV++D+T + ++  A  W
Sbjct: 105 ERFTSMTRVYYKDAHACIVMFDLTQKNTYQNAIRW 1
>32723
          Length = 384

 Score = 79.3 bits (194), Expect = 1e-15,   Method: Compositional matrix adjust.
 Identities = 39/115 (33%), Positives = 64/115 (55%)
 Frame = +2

Query: 79  QERYHSLAPMYYRGAQAAIVVYDITNEESFARAKNWVKELQRQASPNIVIALSGNKADLA 138
           QER+ S+   YYR A A I+VYD+ +++S+     W+ E++  A   ++  L GNK D  
Sbjct: 2   QERFRSITQSYYRSANALILVYDVCSQQSYESLPQWIHEIELYAGTKVLAFLVGNKIDQT 181

Query: 139 NKRAVDFQEAQSYADDNSLLFMETSAKTSMNVNEIFMAIAKKLPKNEPQNPGANS 193
           +KR +     + +A+   + F+ETSAK + NV ++F  IA +L        GA +
Sbjct: 182 DKREIPTHIGKEFAERYEMRFLETSAKEADNVEKLFSTIAYQLTAQAQGTLGAEA 346
>01398
          Length = 1421

 Score = 78.6 bits (192), Expect = 2e-15,   Method: Compositional matrix adjust.
 Identities = 39/102 (38%), Positives = 59/102 (57%), Gaps = 1/102 (0%)
 Frame = -2

Query: 79   QERYHSLAPMYYRGAQAAIVVYDITNEESFARAKNWVKELQRQASPNIVIALS-GNKADL 137
            QER+ S+   YYR +   I+VYDIT   +F   K W +E +    P+  I L  G+K+D 
Sbjct: 1420 QERFRSITRSYYRNSVGVIIVYDITKRSTFENLKQWYEEARNHIEPHKAIFLVLGHKSDR 1241

Query: 138  ANKRAVDFQEAQSYADDNSLLFMETSAKTSMNVNEIFMAIAK 179
             + R V  +E + +A+ + L F ETSAK+  N+ ++F  IAK
Sbjct: 1240 EDARQVTAREGRRFAEMHGLKFFETSAKSGHNIEDVFAQIAK 1115
>19006
          Length = 568

 Score = 78.2 bits (191), Expect = 3e-15,   Method: Compositional matrix adjust.
 Identities = 42/119 (35%), Positives = 64/119 (53%), Gaps = 1/119 (0%)
 Frame = -2

Query: 22  KLVLLGESAVGKSSLVLRFVKGQFHEFQESTIGAAFLTQTVCLDDTTVKFEIWDTAGQER 81
           KLV++G+ A GK+ L++ F K QF E    T+   ++   + +D   V+  +WDTAGQE 
Sbjct: 432 KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVAD-IEVDSKQVELALWDTAGQED 256

Query: 82  YHSLAPMYYRGAQAAIVVYDITNEESFAR-AKNWVKELQRQASPNIVIALSGNKADLAN 139
           Y  L P+ Y      ++ + I + +S     + W  E+ R   PN+ I L GNK DL N
Sbjct: 255 YDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEV-RHFCPNVPIILVGNKKDLRN 82
>09204
          Length = 1051

 Score = 73.2 bits (178), Expect = 8e-14,   Method: Compositional matrix adjust.
 Identities = 40/108 (37%), Positives = 63/108 (58%), Gaps = 4/108 (3%)
 Frame = -3

Query: 81   RYHSLAPMYYRGAQAAIVVYDITNEESFARAKNWVKELQRQASPNIVIALSGNKADLAN- 139
            RY +++ +YYRGA+AAI+ +D+T++ SF R + W+ EL RQ      + + G K DL + 
Sbjct: 1049 RYEAMSRIYYRGAKAAILCFDLTDKSSFDRIRFWIGEL-RQHEEECKLYICGTKFDLVHD 873

Query: 140  ---KRAVDFQEAQSYADDNSLLFMETSAKTSMNVNEIFMAIAKKLPKN 184
               +RAV    A++ ADD      ETS+ T  N+ ++F  IA+   K 
Sbjct: 872  DPERRAVPRSVAKALADDCMAEIYETSSMTGDNIEKLFTKIAEDYMKE 729
>34359
          Length = 1042

 Score = 72.8 bits (177), Expect = 1e-13,   Method: Compositional matrix adjust.
 Identities = 42/141 (29%), Positives = 73/141 (51%), Gaps = 4/141 (2%)
 Frame = +3

Query: 21  FKLVLLGESAVGKSSLVLRFVKGQFHEFQESTIGAAFLTQTVCLDDTTVKFEIWDTAGQE 80
           FKLVL+G      +++V R V G   ++  +T+G              ++F +WDTAGQE
Sbjct: 54  FKLVLVGGRWEWANNIVKRHVTGS*KKY-VATLGVEVHPLQFNTSRGLLRFNVWDTAGQE 230

Query: 81  RYHSLAPMYYRGAQAAIVVYDITNEESFARAKNWVKELQRQASPNIVIALSGNKADLANK 140
           ++  L   YY     AI+++D+T+  ++    NW ++L R    NI I L GNK D+ ++
Sbjct: 231 KFGGLRDGYYIQGTCAIIMFDVTSRVTYKNVPNWHRDLVR-VCENIPIVLCGNKVDIKDR 407

Query: 141 ----RAVDFQEAQSYADDNSL 157
               +A+ F   ++ +   S+
Sbjct: 408 KVKAKAIVFHRKRTCSTTTSV 470
>12339
          Length = 578

 Score = 72.0 bits (175), Expect = 2e-13,   Method: Compositional matrix adjust.
 Identities = 40/106 (37%), Positives = 59/106 (55%), Gaps = 5/106 (4%)
 Frame = -2

Query: 79  QERYHSLAPMYYRGAQAAIVVYDITNEESFARAKNWVKELQRQASP----NIVIALSGNK 134
           QER+ SL   +YRGA   I+VYD+T  ++F    +W +E   QASP    +    + GNK
Sbjct: 577 QERFQSLGVAFYRGADCCILVYDVTEXKTFDSLDSWQREFLNQASPRDPEHFPFVVIGNK 398

Query: 135 ADLANKRAVDFQEAQSY-ADDNSLLFMETSAKTSMNVNEIFMAIAK 179
            DL N R V  +  Q + +    + + ETSAK ++NV + F  +AK
Sbjct: 397 IDLDN-RVVTAKRGQGWCSTKGGIPYFETSAKEAINVEQAFQTVAK 263
>13745
          Length = 1045

 Score = 70.9 bits (172), Expect = 4e-13,   Method: Compositional matrix adjust.
 Identities = 40/105 (38%), Positives = 54/105 (51%), Gaps = 4/105 (3%)
 Frame = +2

Query: 79  QERYHSLAPMYYRGAQAAIVVYDITNEESFARAKNWVKELQRQASP----NIVIALSGNK 134
           QER+ SL   +YRGA   ++VYD+T   SF    +W  E   QASP    +    + GNK
Sbjct: 2   QERFQSLGVAFYRGADCCVLVYDVTAPNSFKNLDSWRDEFLIQASPRDPEHFPFVVLGNK 181

Query: 135 ADLANKRAVDFQEAQSYADDNSLLFMETSAKTSMNVNEIFMAIAK 179
            DL N++    +  Q     N + + ETSAK  +NV   F  IAK
Sbjct: 182 VDLDNRQVSTRRAQQWCQSKNDIPYYETSAKEGINVEMAFQTIAK 316
>11728
          Length = 635

 Score = 62.8 bits (151), Expect = 9e-11,   Method: Compositional matrix adjust.
 Identities = 36/118 (30%), Positives = 56/118 (47%), Gaps = 1/118 (0%)
 Frame = -1

Query: 21  FKLVLLGESAVGKSSLVLRFVKGQFHEFQESTIGAAFLTQTVCLDDTTVKFEIWDTAGQE 80
            K V++G+ AVGK+ L++ +    F      T+   + +  V +D   +   +WDTAGQE
Sbjct: 488 IKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNY-SANVMVDSKPINLGLWDTAGQE 312

Query: 81  RYHSLAPMYYRGAQAAIVVYDITNEESFARAK-NWVKELQRQASPNIVIALSGNKADL 137
            Y  L P+ Y      ++ + + +  SF   K  W  E+     PN  I L G K DL
Sbjct: 311 DYDRLRPLSYPQTDVFLICFSLISPASFENVKAKWYPEVSHHC-PNTPIILVGTKLDL 141
>00858
          Length = 1658

 Score = 60.8 bits (146), Expect = 4e-10,   Method: Compositional matrix adjust.
 Identities = 46/166 (27%), Positives = 90/166 (54%), Gaps = 1/166 (0%)
 Frame = -2

Query: 17   KICQFKLVLLGESAVGKSSLVLRFVKGQFHEFQESTIGAAFLTQTVCLDDTTVKFEIWDT 76
            ++ ++KLV++G   VGKS+L ++  +  F E  + T   +   Q V +D  T   +I DT
Sbjct: 1600 QMTEYKLVVVGAGGVGKSALTIQLXQNHFVEEYDPTXEDSXRKQVV-IDGETCLLDILDT 1424

Query: 77   AGQERYHSLAPMYYRGAQAAIVVYDITNEESFARAKNWVKELQR-QASPNIVIALSGNKA 135
            AGQE   ++     R  +  + V+ + N +SF     + ++++R + +  + + L GNK 
Sbjct: 1423 AGQEEXSAMRDQCMRTGEGFLCVFAVXNLKSFEDINQYREQIKRVKDADEVPMVLVGNKV 1244

Query: 136  DLANKRAVDFQEAQSYADDNSLLFMETSAKTSMNVNEIFMAIAKKL 181
            DL   R V+ ++ +  A+   + ++ETSAKT   V++ F  + +++
Sbjct: 1243 DLP-IRNVEQRQGKHMAELYHIPYVETSAKTRQGVDDAFYTLVREI 1109
>27191
          Length = 443

 Score = 57.0 bits (136), Expect = 5e-09,   Method: Compositional matrix adjust.
 Identities = 24/103 (23%), Positives = 55/103 (53%)
 Frame = +1

Query: 33  KSSLVLRFVKGQFHEFQESTIGAAFLTQTVCLDDTTVKFEIWDTAGQERYHSLAPMYYRG 92
           K+ L+  F + +F++  + T+G  +  +   ++   ++  +WD +G   Y  +    Y G
Sbjct: 1   KTCLIKHFCESKFNQGYQPTVGVDYGFKIQTVNGVDMRVHMWDLSGSNEYLDVRNELYTG 180

Query: 93  AQAAIVVYDITNEESFARAKNWVKELQRQASPNIVIALSGNKA 135
           + A  +V+D++N  SF    +W++E+ R A+ + +  + GN+ 
Sbjct: 181 SDAIFIVFDVSNTPSFEALDSWLREINRFATGSPLNVIVGNRV 309
>10708
          Length = 2775

 Score = 37.4 bits (85), Expect(2) = 3e-08,   Method: Compositional matrix adjust.
 Identities = 25/76 (32%), Positives = 36/76 (47%), Gaps = 13/76 (17%)
 Frame = -3

Query: 112  KNWVKELQRQASPNIVIALSGNKADLAN------------KRAVDFQEAQSYADD-NSLL 158
            K W  E+ R   PN+ I L GNK DL N            +  V   E ++ ++  N+  
Sbjct: 2590 KKWTPEV-RHFCPNVPIILVGNKKDLRNDENTKRELMKMKQEPVRLDEGRAMSEKINAYS 2414

Query: 159  FMETSAKTSMNVNEIF 174
            ++E SAKT   V E+F
Sbjct: 2413 YLECSAKTKEGVREVF 2366

 Score = 36.6 bits (83), Expect(2) = 3e-08,   Method: Compositional matrix adjust.
 Identities = 14/40 (35%), Positives = 22/40 (55%)
 Frame = -2

Query: 69   VKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNEESF 108
            V+  +WDTAGQE Y  L P+ Y      ++ + I + +S 
Sbjct: 2723 VELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSL 2604
>34597
          Length = 773

 Score = 54.3 bits (129), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 32/112 (28%), Positives = 57/112 (50%), Gaps = 4/112 (3%)
 Frame = -2

Query: 107 SFARAKNWVKELQRQASPNIVIALSGNKADLANKRAVDFQEAQSYADDNSLLFMETSAKT 166
           SF     W++ +   A+ ++   + GNK D+ +KR V  +  ++ A ++S+ FMETSAK+
Sbjct: 709 SFENIVKWLRNIDEHANEDVEKMILGNKCDMTDKRVVSKERGEAIAREHSIRFMETSAKS 530

Query: 167 SMNVNEIFMAIAKK-LPKNEPQNPGANSAR---GRGVDLTEPAQPARSQCCS 214
           ++N+   F  +A+  L K   +    N  R    RG        P  ++CC+
Sbjct: 529 NINIERAFCELAEAILDKTAGRESAENPERVVIDRG---NSDKAPGYNKCCA 383
>14775
          Length = 380

 Score = 53.5 bits (127), Expect = 6e-08,   Method: Compositional matrix adjust.
 Identities = 42/158 (26%), Positives = 61/158 (38%), Gaps = 7/158 (4%)
 Frame = -2

Query: 33  KSSLVLRFVKGQFHEFQESTIGAAFLTQTVC-------LDDTTVKFEIWDTAGQERYHSL 85
           K+ L+ R+ KG F +    TI        +C        D   V++ +WDT G E Y SL
Sbjct: 379 KTCLLRRYQKGFFMDRTMPTIAV------LCSEFNESRTDPLNVRYTLWDTGGAETYRSL 218

Query: 86  APMYYRGAQAAIVVYDITNEESFARAKNWVKELQRQASPNIVIALSGNKADLANKRAVDF 145
              ++RGAQ A++VYD+T E                                        
Sbjct: 217 WVSHFRGAQVALLVYDVTCE---------------------------------------- 158

Query: 146 QEAQSYADDNSLLFMETSAKTSMNVNEIFMAIAKKLPK 183
              Q++A      F ETS+ T  NV+ +F  IA  L +
Sbjct: 157 -RGQAFATQCGYTFFETSSVTGKNVDAVFWEIAFILAR 47
>19656
          Length = 428

 Score = 52.4 bits (124), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 31/103 (30%), Positives = 50/103 (48%), Gaps = 2/103 (1%)
 Frame = +3

Query: 22  KLVLLGESAVGKSSLVLRFVKGQFHEFQESTIGAAFLTQTVCLDDTTVKFEIWDTAGQER 81
           K V++G+ AVGK+ L++ +    F      T+   + +  V +D   V   +WDTAGQE 
Sbjct: 117 KCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNY-SANVMVDGRPVNLGLWDTAGQED 293

Query: 82  YHSLAPMYYRGAQAAIVVYDITNEESF--ARAKNWVKELQRQA 122
           Y  L P+ Y      ++ + + +  SF   RAK W  E+    
Sbjct: 294 YDRLRPLSYPQTDVFLLCFSVASPASFENIRAK-WYPEVNHHC 419
>31291
          Length = 446

 Score = 49.7 bits (117), Expect = 8e-07,   Method: Compositional matrix adjust.
 Identities = 27/75 (36%), Positives = 39/75 (52%), Gaps = 2/75 (2%)
 Frame = -1

Query: 71  FEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNEESFARAK-NWVKELQRQASPNIVIA 129
            ++WDTAGQE Y  L P+ Y      ++ + + +E S    K  W  E+ R   P++ I 
Sbjct: 446 LQLWDTAGQEDYDRLRPLAYPNTDVFMLXFSLMSEASMKNVKVKWYPEI-RHHDPHVPIV 270

Query: 130 LSGNKADL-ANKRAV 143
           L G K DL  +K AV
Sbjct: 269 LVGTKLDLRQDKEAV 225
>00552
          Length = 455

 Score = 47.8 bits (112), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 19/46 (41%), Positives = 26/46 (56%)
 Frame = -3

Query: 73  IWDTAGQERYHSLAPMYYRGAQAAIVVYDITNEESFARAKNWVKEL 118
           IWDTAGQERY SL   +YRG    ++ + + N +S     +W  E 
Sbjct: 147 IWDTAGQERYKSLRTPFYRGTDCCLLTFSVDNLKSLQSLSDWYDEF 10

 Score = 45.1 bits (105), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 24/48 (50%), Positives = 30/48 (62%)
 Frame = -1

Query: 21  FKLVLLGESAVGKSSLVLRFVKGQFHEFQESTIGAAFLTQTVCLDDTT 68
            K+VLLG+  VGKSSL+ RFV  +F      TIG  FLT+ V +D  T
Sbjct: 443 LKVVLLGDGGVGKSSLMNRFVSNKFDAQSFHTIGVEFLTKDVVVDGET 300
>08153
          Length = 1703

 Score = 45.4 bits (106), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 34/124 (27%), Positives = 60/124 (48%), Gaps = 4/124 (3%)
 Frame = +1

Query: 20  QFKLVLLGESAVGKSSLVLRFVKGQFHEFQESTIGAAFLTQTVCLDDTTVKFEIWDTAGQ 79
           + +++++G  A GK++++ +   G+       TIG  F  +TV  +   + F +WD  GQ
Sbjct: 82  EVRILMVGLDAAGKTTILYKLKLGEIVT-TIPTIG--FNVETV--EYKNISFTVWDVGGQ 246

Query: 80  ERYHSLAPMYYRGAQAAIVVYDITNEESFARAKNWVKELQRQASP----NIVIALSGNKA 135
           ++   L   Y++  Q  I V D  + E    AK   +EL R  +     + +I +  NK 
Sbjct: 247 DKIRPLWRHYFQNTQGLIFVVDSNDRERINEAK---EELARMLNEDDLRDAIILVFANKQ 417

Query: 136 DLAN 139
           DL N
Sbjct: 418 DLPN 429
>09827
          Length = 1201

 Score = 42.7 bits (99), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 31/125 (24%), Positives = 59/125 (47%), Gaps = 4/125 (3%)
 Frame = -3

Query: 22   KLVLLGESAVGKSSLVLRFVKGQFHEFQESTIGAAFLTQTVCLDDTTVKFEIWDTAGQER 81
            +++++G  A GK++++ +   G   E   +     F  +TV  +   + F +WD  GQ++
Sbjct: 1109 RILMVGLDAAGKTTILYKLKLG---EIVTTIPTIGFNVETV--EYKNISFTVWDVGGQDK 945

Query: 82   YHSLAPMYYRGAQAAIVVYDITNEESFARAKNWVKELQRQASP----NIVIALSGNKADL 137
               L   Y++  Q  I V D  ++E    A+   +EL R  +     + V+ +  NK DL
Sbjct: 944  IRPLWRHYFQNTQGLIFVVDSNDKERVQEAR---EELTRMLNEDELRDAVLLVFANKQDL 774

Query: 138  ANKRA 142
             +  A
Sbjct: 773  PHAMA 759
>10862
          Length = 2896

 Score = 41.2 bits (95), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 22/74 (29%), Positives = 35/74 (47%), Gaps = 4/74 (5%)
 Frame = -3

Query: 70   KFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNEESFARAKNWVKELQR----QASPN 125
            +F +WD  GQ++   L   YY G Q  I V D  + +    A+   +EL R    +   +
Sbjct: 2483 QFNVWDVGGQDKIRPLWRHYYTGTQGLIFVVDCADRDRIDEAR---QELHRIINDREMRD 2313

Query: 126  IVIALSGNKADLAN 139
             +I +  NK DL +
Sbjct: 2312 AIILIFANKQDLPD 2271
>18509
          Length = 625

 Score = 34.7 bits (78), Expect = 0.028,   Method: Compositional matrix adjust.
 Identities = 19/63 (30%), Positives = 36/63 (57%)
 Frame = -3

Query: 128 IALSGNKADLANKRAVDFQEAQSYADDNSLLFMETSAKTSMNVNEIFMAIAKKLPKNEPQ 187
           + L GNK DL   R V+ ++ +  A+   + ++ETSAKT   V++ F  + +++ K + +
Sbjct: 521 MVLVGNKVDLPI-RNVEQRQGKHMAELYHIPYVETSAKTRQGVDDAFYTLVREIRKYKER 345

Query: 188 NPG 190
             G
Sbjct: 344 KDG 336
>06994
          Length = 429

 Score = 34.3 bits (77), Expect = 0.039,   Method: Compositional matrix adjust.
 Identities = 15/28 (53%), Positives = 22/28 (78%)
 Frame = +3

Query: 20 QFKLVLLGESAVGKSSLVLRFVKGQFHE 47
          ++KLV+LG   VGKS+L ++FV+G F E
Sbjct: 54 EYKLVVLGSGGVGKSALTVQFVQGIFVE 137
>33605
          Length = 888

 Score = 32.0 bits (71), Expect = 0.21,   Method: Compositional matrix adjust.
 Identities = 22/93 (23%), Positives = 40/93 (43%)
 Frame = +1

Query: 20  QFKLVLLGESAVGKSSLVLRFVKGQFHEFQESTIGAAFLTQTVCLDDTTVKFEIWDTAGQ 79
           + +L++LG    GK++++ +F  G+  +    T+G    T    L+    K  +WD  GQ
Sbjct: 496 EVRLLMLGLDNAGKTTILKKF-NGEDIDTISPTLGFNIKT----LEHRGFKLNVWDVGGQ 660

Query: 80  ERYHSLAPMYYRGAQAAIVVYDITNEESFARAK 112
           +   S    Y+      + V D  +    A  K
Sbjct: 661 QSLRSYWRNYFESTDGLVWVVDSADRMRIADCK 759
>34156
          Length = 348

 Score = 30.4 bits (67), Expect = 0.60,   Method: Compositional matrix adjust.
 Identities = 17/53 (32%), Positives = 30/53 (56%)
 Frame = -1

Query: 20  QFKLVLLGESAVGKSSLVLRFVKGQFHEFQESTIGAAFLTQTVCLDDTTVKFE 72
           +F L+++GES +GKS+LV        +  +     +  + QTV +D +TV+ E
Sbjct: 198 EFTLMVVGESGLGKSTLVNSLFLTDLYPERHIPSASEKIQQTVKIDASTVEIE 40
>30516
          Length = 606

 Score = 28.1 bits (61), Expect = 3.0,   Method: Compositional matrix adjust.
 Identities = 17/59 (28%), Positives = 25/59 (42%)
 Frame = +2

Query: 20  QFKLVLLGESAVGKSSLVLRFVKGQFHEFQESTIGAAFLTQTVCLDDTTVKFEIWDTAG 78
           + ++VLLG++  GKSSL    +          T      TQ  C D      ++ DT G
Sbjct: 170 RLRVVLLGKTGSGKSSLGNTLLGKDTFRVMPGTSSGTKDTQRECADRFGTMIQVTDTPG 346
>11203
          Length = 1195

 Score = 27.7 bits (60), Expect = 3.3,   Method: Compositional matrix adjust.
 Identities = 19/78 (24%), Positives = 36/78 (46%)
 Frame = -2

Query: 40   FVKGQFHEFQESTIGAAFLTQTVCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVV 99
            ++ GQF      T+G  +    +  D   V+ + +D+A Q  Y +   + + GA   +V+
Sbjct: 1059 YIIGQFAFGHAETLGPLYAALGLFNDTEPVRADNFDSADQRTYRTSLILPF-GANLQLVL 883

Query: 100  YDITNEESFARAKNWVKE 117
            Y+   EE +   +N   E
Sbjct: 882  YECEPEEQYLNPENEAGE 829
>19310
          Length = 784

 Score = 25.0 bits (53), Expect(2) = 4.6,   Method: Compositional matrix adjust.
 Identities = 14/36 (38%), Positives = 19/36 (52%)
 Frame = -2

Query: 8   RPNGPNTGNKICQFKLVLLGESAVGKSSLVLRFVKG 43
           RP G ++   +C F L L G  + G + LVL  V G
Sbjct: 459 RPGGRSS---VCGFSLRLCGPQSCGHTWLVLWXVLG 361

 Score = 20.8 bits (42), Expect(2) = 4.6,   Method: Compositional matrix adjust.
 Identities = 8/18 (44%), Positives = 12/18 (66%)
 Frame = -3

Query: 68  TVKFEIWDTAGQERYHSL 85
            V ++++DT   ERY SL
Sbjct: 302 VVSWKLYDTGYTERYLSL 249
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|225543181|ref|NP_001013398.2| dynein, cytoplasmic 1
light intermediate chain 2 [Mus musculus]
         (492 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

06254                                                                 273   1e-78
01774                                                                  34   0.12 
30505                                                                  33   0.21 
19777                                                                  30   1.6  
>06254
          Length = 2204

 Score =  273 bits (698), Expect(2) = 1e-78,   Method: Compositional matrix adjust.
 Identities = 134/216 (62%), Positives = 170/216 (78%), Gaps = 8/216 (3%)
 Frame = +2

Query: 166 PPEEMRDLERKFMKEFQDYIEPEEGCQGSPQR--RG---PLTSG--SDEDSVALPLGDNV 218
           P ++MRD E+  ++ FQDY  PEEG Q S Q   RG   PL     +D+D V LPLGDNV
Sbjct: 215 PQKKMRDYEQSLVRFFQDYTAPEEG-QSSSQAPPRGDANPLHPALMTDDDKVVLPLGDNV 391

Query: 219 LTHNLGIPVLVVCTKCDAMSVLEKEHDYRDEHLDFIQAHLRRFCLQYGAALIYTSVKEEK 278
           LTHNLGIPV+VV TKCDA+S LEK+HD+R+EH DFIQ ++R+FCL+YGA L YTSVK+E+
Sbjct: 392 LTHNLGIPVVVVLTKCDAISSLEKDHDFREEHFDFIQQYVRKFCLKYGAGLFYTSVKDER 571

Query: 279 NLDLLYKYIVHKTYGFHFTIPALVVEKDAVFIPAGWDNEKKIAILHENFTTVKPEDAYED 338
           N +LLY+Y+VH+ YGF FT PA VV++D+VF+P GWDNEKKI+IL+EN ++VKPED  ED
Sbjct: 572 NCELLYRYLVHRIYGFPFTTPAYVVDRDSVFVPCGWDNEKKISILYENMSSVKPEDGLED 751

Query: 339 FIVKPPVRKLVH-DKELAAEDEQVFLMKQQSLLAKQ 373
            IV+P +RK V  D E+ AEDEQV+LMK Q++LAKQ
Sbjct: 752 VIVRPVLRKPVQRDAEVFAEDEQVYLMKLQAVLAKQ 859

 Score = 38.9 bits (89), Expect(2) = 1e-78,   Method: Compositional matrix adjust.
 Identities = 14/31 (45%), Positives = 22/31 (70%)
 Frame = +3

Query: 98  RDDHTRCNVWILDGDLYHKGLLKFAVSAESL 128
           RD+  R NVW+LDGD  H  L+K+A++ ++ 
Sbjct: 9   RDEQARLNVWVLDGDQSHTALMKYALTEDNF 101

 Score = 57.0 bits (136), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 23/51 (45%), Positives = 37/51 (72%)
 Frame = +1

Query: 127 SLRETLVIFVADMSRPWTIMESLQKWASVLREHIDKMKIPPEEMRDLERKF 177
           +  +++V+ VA M++PW+I +SL KW +VL +HIDK++IPPE+   L  K 
Sbjct: 97  TFEDSMVMLVASMAQPWSIADSLTKWITVLSQHIDKLRIPPEKNERLXTKL 249

 Score = 38.9 bits (89), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 16/21 (76%), Positives = 21/21 (100%)
 Frame = +1

Query: 424  ASEGVLASFFNSLLSKKTGSP 444
            A+EG+LA+FFNSLL+KKTG+P
Sbjct: 1012 ATEGMLANFFNSLLNKKTGAP 1074
>01774
          Length = 856

 Score = 34.3 bits (77), Expect = 0.12,   Method: Compositional matrix adjust.
 Identities = 33/116 (28%), Positives = 49/116 (42%), Gaps = 2/116 (1%)
 Frame = -2

Query: 379 RTSESPARGPSGSPRTQGRGGPASVPSASPGTSVKK-PDPNIKNNAASEGVLASFFNSLL 437
           R + +PA+ P  SP  +G+  PA     SP   +KK P   IK + A     +       
Sbjct: 456 RINPAPAKTPRKSPAGRGQSSPAPTSRKSPAHKIKKSPAHKIKKSPAQTSKKSCI----- 292

Query: 438 SKKTGSPGSPSAGGVQSTAKKSGQKTVLSNVQEELD-RMTRKPDSMVTNSSTENEA 492
            ++T  P       VQ T K   Q+T+   VQE    + T KP    T ++  +E 
Sbjct: 291 -QETTKPQFQETIIVQETMKPCLQETIKPQVQETTKVQETMKPQDQKTMNNQAHET 127
>30505
          Length = 549

 Score = 33.5 bits (75), Expect = 0.21,   Method: Compositional matrix adjust.
 Identities = 16/62 (25%), Positives = 29/62 (46%)
 Frame = +3

Query: 36  WSSILSEVSTRARSKLPSGKNILVFGEDGSGKTTLMTKLQGAEHGKKGRGLEYLYLSVHD 95
           ++ +++      R +  +G  ILV G+ G+GK+ L   L G +    GR       ++H 
Sbjct: 255 FAGLMATTGDEERGRTDNGHRILVIGKAGNGKSALCNALTGTQQFPTGRSFAATTRTMHS 434

Query: 96  ED 97
            D
Sbjct: 435 FD 440
>19777
          Length = 671

 Score = 30.4 bits (67), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 15/34 (44%), Positives = 20/34 (58%)
 Frame = -1

Query: 50  KLPSGKNILVFGEDGSGKTTLMTKLQGAEHGKKG 83
           KL SG +ILV G+ G GKT+L+  + G      G
Sbjct: 569 KLHSGTSILVTGDSGCGKTSLLRVIAGLWKSSTG 468
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|23510269|ref|NP_700452.1| eukaryotic translation
initiation factor 2C, 1 [Mus musculus]
         (857 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

19404                                                                 290   1e-78
06972                                                                 274   1e-73
02516                                                                 111   1e-24
06326                                                                  64   3e-10
22922                                                                  50   5e-06
01764                                                                  38   0.021
>19404
          Length = 576

 Score =  290 bits (743), Expect = 1e-78,   Method: Compositional matrix adjust.
 Identities = 144/192 (75%), Positives = 161/192 (83%), Gaps = 6/192 (3%)
 Frame = +1

Query: 523 KTPVYAEVKRVGDTLLGMATQCVQVKNAVKTSPQTLSNLCLKINVKLGGINNILVPHQRS 582
           KTPVYAEVKRVGD + G+ATQCVQ KN  KT+PQTLSNLCLKINVKLGG+N+IL+P  R 
Sbjct: 1   KTPVYAEVKRVGDIMFGLATQCVQSKNVNKTTPQTLSNLCLKINVKLGGVNSILLPSIRP 180

Query: 583 AVFQQPVIFLGADVTHPPAGDGKKPSITAVVGSMDAHPSRYCATVRVQRPRQEIIEDLSY 642
           AVF++PVIFLGADVTHPPAGD  KPSI AVVGSMDAHPSRY A VRVQ  RQE+I +L+ 
Sbjct: 181 AVFREPVIFLGADVTHPPAGDSSKPSIAAVVGSMDAHPSRYAAAVRVQEHRQEVIYELAT 360

Query: 643 MVRELLIQFYKSTRFKPTRIIFYRDGVPEGQLP-----QILHYELLAIRDACIKLEKDYQ 697
           MVRELLIQFY+STRFKPTRIIFYRDGV EGQ       Q+L +EL AIR+AC KLE DY+
Sbjct: 361 MVRELLIQFYRSTRFKPTRIIFYRDGVSEGQFHASTYLQVLSHELRAIREACTKLEGDYR 540

Query: 698 PG-ITYIVVQKR 708
           PG  T+IVVQKR
Sbjct: 541 PGNTTFIVVQKR 576
>06972
          Length = 1038

 Score =  274 bits (700), Expect = 1e-73,   Method: Compositional matrix adjust.
 Identities = 127/158 (80%), Positives = 137/158 (86%)
 Frame = +1

Query: 700 ITYIVVQKRHHTRLFCADKNERIGKSGNIPAGTTVDTNITHPFEFDFYLCSHAGIQGTSR 759
           IT+IVVQKRHHTRLFCA+K E+ GKSGNIPAGTTVD  ITHP EFDFYLCSH GIQGT R
Sbjct: 4   ITFIVVQKRHHTRLFCAEKKEQSGKSGNIPAGTTVDVGITHPTEFDFYLCSHQGIQGTXR 183

Query: 760 PSHYYVLWDDNRFTADELQILTYQLCHTYVRCTRSVSIPAPAYYARLVAFRARYHLVDKE 819
           PSHY+VLWDDN F +DELQ LTYQLCHTYVRCTRSVSIPAPAYYA LVAFRARYHLV+KE
Sbjct: 184 PSHYHVLWDDNHFDSDELQCLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVEKE 363

Query: 820 HDSGEGSHISGQSNGRDPQALAKAVQVHQDTLRTMYFA 857
           HDSGEGSH SG S  R P A+A+A+ VH DT + MYFA
Sbjct: 364 HDSGEGSHQSGSSEDRTPGAMARAITVHADTKKVMYFA 477
>02516
          Length = 2764

 Score =  111 bits (277), Expect = 1e-24,   Method: Compositional matrix adjust.
 Identities = 114/439 (25%), Positives = 189/439 (43%), Gaps = 35/439 (7%)
 Frame = +1

Query: 434  DMRGKQFYNGIEIKVWAIACFAPQKQCREEVLKNFTDQLRKISKDAGMPIQGQPCFCKYA 493
            DMRGK+    + ++ W +     QK+  ++  K+    L K+    GM I   P   +  
Sbjct: 1471 DMRGKKMVLAVPLQRWLLVV---QKRSTDKA-KDLAGILAKVGPPMGMNI-APPRMVQID 1635

Query: 494  QG-ADSVEPMFRHLKNTYSG-LQLIIVILPG-KTPVYAEVKRVGDTLLGMATQCVQVKNA 550
            Q   DS     R  +N   G  QL++ +L   K   Y  +K+     + +A+Q V  K  
Sbjct: 1636 QDRNDSYIHALR--ENIREGETQLVVCVLSNNKKDRYDAIKKYCCIDMPVASQMVTDKTL 1809

Query: 551  VKTSPQTLSNLCLKI----NVKLGGINNILVPHQRSAVFQQPV-----IFLGADVTHPPA 601
              ++ Q L ++  KI    N KLGG+           V+  P+     + +G D  H  A
Sbjct: 1810 --SNKQRLMSVATKIAIQMNCKLGGV-----------VWVCPIPLVNTMIVGIDTYHDSA 1950

Query: 602  GDGKKPSITAVVGSMDAHPSRYCATVRVQRPRQEIIEDLSYMVRELLIQFYKSTRFK-PT 660
              G+  S+  +V ++++  SRY +T   Q    E+ + L + +   L  + +    K P 
Sbjct: 1951 VRGQ--SVGGIVATVNSDYSRYFSTCTFQMRHLELQDKLYFSIIACLKAYGRENNNKYPD 2124

Query: 661  RIIFYRDGVPEGQLPQILHYELLAIRDACIKLEK--DYQPGITYIVVQKRHHTRLF---- 714
            +++ +RDGV +GQL  +  +E+  +R A  K  +  D    + YI+V+KR + R F    
Sbjct: 2125 KVVVFRDGVGDGQLQLVYEHEIPQVRRALNKCAERFDMTIKLAYIIVKKRTNARFFQEGV 2304

Query: 715  ----------------CADKNERIGKSGNIPAGTTVDTNITHPFEFDFYLCSHAGIQGTS 758
                                  +     N   GT +D   T P  FDF+L S +   GT 
Sbjct: 2305 IMESGPGGARGGRGGGGGAGGGQRRGLTNPGPGTIIDNVATKPTWFDFFLISQSVRDGTV 2484

Query: 759  RPSHYYVLWDDNRFTADELQILTYQLCHTYVRCTRSVSIPAPAYYARLVAFRARYHLVDK 818
             P+H+ V++D+    ++  Q + Y+LCH Y     ++ +PAP  YA  +AF         
Sbjct: 2485 SPTHFNVIFDELDIKSEYYQRMAYKLCHMYYNWQGTIRVPAPCMYAHKLAF--------- 2637

Query: 819  EHDSGEGSHISGQSNGRDP 837
                     + GQS  RDP
Sbjct: 2638 ---------LVGQSLHRDP 2667

 Score = 33.5 bits (75), Expect = 0.35,   Method: Compositional matrix adjust.
 Identities = 13/31 (41%), Positives = 21/31 (67%), Gaps = 2/31 (6%)
 Frame = +3

Query: 33  GKPIKLLANYFEVDI--PKIDVYHYEVDIKP 61
           G+PI L+ N+F+V++  P   +Y Y VD +P
Sbjct: 357 GRPINLIGNFFKVNLTTPNWRIYQYHVDFQP 449
>06326
          Length = 486

 Score = 63.9 bits (154), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 44/136 (32%), Positives = 72/136 (52%), Gaps = 5/136 (3%)
 Frame = -3

Query: 589 VIFLGADVTHPPAGDGKKPSITAVVGSMDAHPS-RYCATVRVQRPRQEIIEDLSYMVREL 647
           ++ +G DV H  +   K  S  A+V +MD   S RY ++V      QE+   +S  +   
Sbjct: 403 LMTVGFDVCH--SSKDKNKSYGALVATMDLKLSTRYYSSVTEHMKGQELSNQMSVNMTCA 230

Query: 648 LIQFYKSTRFKPTRIIFYRDGVPEGQLPQILHYELLAIRDACIKL----EKDYQPGITYI 703
           L  + K     P RI+F+RDGV +GQL Q+++ E+  ++D   ++     KD    + +I
Sbjct: 229 LKAYRKHHGTLPERILFFRDGVGDGQLEQVVNTEVKYLKDQLDQIYKSAGKDVGCRMAFI 50

Query: 704 VVQKRHHTRLFCADKN 719
           VV KR +TR F  ++N
Sbjct: 49  VVSKRINTRYFARNRN 2
>22922
          Length = 970

 Score = 49.7 bits (117), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 31/95 (32%), Positives = 52/95 (54%), Gaps = 1/95 (1%)
 Frame = +3

Query: 589 VIFLGADVTHPPAGDGKKPSITAVVGSMDAHPS-RYCATVRVQRPRQEIIEDLSYMVREL 647
           ++ +G DV H  +   K  S  A+V +MD   S RY ++V      QE+   +S  +   
Sbjct: 84  LMTVGFDVCH--SSKDKNKSYGAIVATMDLKLSTRYYSSVTEHMKGQELSNQMSVNMTCA 257

Query: 648 LIQFYKSTRFKPTRIIFYRDGVPEGQLPQILHYEL 682
           L  + ++    P RI+F+RDGV +GQL Q+++ E+
Sbjct: 258 LKAYRENHGSLPERILFFRDGVGDGQLAQVVNTEV 362

 Score = 43.1 bits (100), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 20/55 (36%), Positives = 33/55 (60%)
 Frame = +2

Query: 755 QGTSRPSHYYVLWDDNRFTADELQILTYQLCHTYVRCTRSVSIPAPAYYARLVAF 809
           +GT  P+ Y V+ D+    AD+LQ+L+Y++ H Y   + +  +PA   YA  +AF
Sbjct: 569 KGTVSPTSYNVIQDNMGLDADKLQMLSYKMTHLYYNWSGTCRVPAVCQYAHKLAF 733
>01764
          Length = 441

 Score = 37.7 bits (86), Expect = 0.021,   Method: Compositional matrix adjust.
 Identities = 22/84 (26%), Positives = 36/84 (42%)
 Frame = -3

Query: 754 IQGTSRPSHYYVLWDDNRFTADELQILTYQLCHTYVRCTRSVSIPAPAYYARLVAFRARY 813
           +     P  + V++D+    ++  Q + Y+LCH Y     ++ +PAP  YA  +AF    
Sbjct: 292 VTAQCHPLTFNVIFDELDIKSEYYQRMAYKLCHMYYNWQGTIRVPAPCMYAHKLAF---- 125

Query: 814 HLVDKEHDSGEGSHISGQSNGRDP 837
                         + GQS  RDP
Sbjct: 124 --------------LVGQSLHRDP 95

 Score = 30.0 bits (66), Expect = 4.3,   Method: Composition-based stats.
 Identities = 11/22 (50%), Positives = 15/22 (68%)
 Frame = -2

Query: 742 FEFDFYLCSHAGIQGTSRPSHY 763
           FEFDF+L S +   GT  P+H+
Sbjct: 329 FEFDFFLISQSVRDGTVSPTHF 264
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|110625979|ref|NP_080283.3| eukaryotic translation
elongation factor 1 gamma [Mus musculus]
         (437 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

23211                                                                 288   2e-78
10621                                                                 282   2e-76
20405                                                                 241   3e-64
20209                                                                  40   0.002
37790                                                                  39   0.004
28739                                                                  30   1.7  
08076                                                                  29   3.2  
28559                                                                  28   9.7  
>23211
          Length = 1156

 Score =  288 bits (738), Expect = 2e-78,   Method: Compositional matrix adjust.
 Identities = 145/299 (48%), Positives = 191/299 (63%)
 Frame = +1

Query: 139 LGLLDTHLKTRTFLVGERVTLADITVVCTLLWLYKQVLEPSFRQAFPNTNRWFLTCINQP 198
           L +L+ +L TRT+LVGE VT ADI++ C L+ LY+QV++P FR+ F N NRWF T +NQP
Sbjct: 1   LTVLNDYLLTRTYLVGESVTQADISLACNLIMLYEQVMDPEFRKPFQNVNRWFXTLVNQP 180

Query: 199 QFRAILGEVKLCEKMAQFDAKKFAESQPKKDTPRKEKGSXXXXXXXXXXXXXXXXXXXXX 258
            F+A+ G+V L +KMAQFDAKK+ +           +G                      
Sbjct: 181 NFKAVAGDVTLAQKMAQFDAKKYGDLHGG-------QGDKKKEKKEKAPKQQEPKKEKAK 339

Query: 259 XXXXMDECEQALAAEPKAKDPFAHLPKSTFVLDEFKRKYSNEDTLSVALPYFWEHFDKDG 318
                ++ E   A E  +KDPF   PK  + +DE+KR YSN DT   ALPYFW  F+K+ 
Sbjct: 340 PKEPEEDDEPPKAKE--SKDPFLAFPKGNWDMDEWKRTYSNLDTEKEALPYFWSKFEKEN 513

Query: 319 WSLWYAEYRFPEELTQTFMSCNLITGMFQRLDKLRKNAFASVILFGTNNSSSISGVWVFR 378
           +S+WY EY       + F +CNL++GMFQRLDK+RK+AF SV +FGT+N +SISG+W +R
Sbjct: 514 YSVWYGEYTEDVSDMKIFQTCNLVSGMFQRLDKMRKHAFGSVCIFGTDNKASISGIWFWR 693

Query: 379 GQELAFPLSPDWQVDYESYTWRKLDPGSEETQTLVREYFSWEGTFQHVGKAVNQGKIFK 437
            QELAF LSPDWQVDYESY W KL+P    T+ +++EYF WEG F   GK  NQGKI+K
Sbjct: 694 SQELAFTLSPDWQVDYESYKWTKLNPDDPTTKKMIKEYFMWEGDF--XGKKFNQGKIYK 864
>10621
          Length = 1304

 Score =  282 bits (722), Expect = 2e-76,   Method: Compositional matrix adjust.
 Identities = 132/223 (59%), Positives = 170/223 (76%)
 Frame = +2

Query: 1   MAAGTLYTYPENWRAFKALIAAQYSGAQVRVLSAPPHFHFGQTNRTPEFLRKFPAGKVPA 60
           MAAGTLYT+P N+RA+KALIAA+YSGA V+V    P F FG+TNR+ +FL+KFP GKVPA
Sbjct: 14  MAAGTLYTFPNNFRAYKALIAARYSGADVKV---DPTFKFGETNRSADFLKKFPLGKVPA 184

Query: 61  FEGDDGFCVFESNAIAYYVSNEELRGSTPEAAAQVVQWVSFADSDIVPPASTWVFPTLGI 120
           F   +G  + ESNAIA YV N++L+G T EAAAQV QW+ FAD++I+P   TWVFP LGI
Sbjct: 185 FSAKNGLNLSESNAIAQYVGNKKLQGETAEAAAQVSQWIDFADNEILPSVCTWVFPCLGI 364

Query: 121 MHHNKQATENAKEEVKRILGLLDTHLKTRTFLVGERVTLADITVVCTLLWLYKQVLEPSF 180
              NKQ TE AK +V + L +L+ +L TRT+LVGE VT ADI++ C L+ LY+QV++P F
Sbjct: 365 TQFNKQETERAKAQVTKALTVLNDYLLTRTYLVGESVTQADISLACNLIMLYEQVMDPEF 544

Query: 181 RQAFPNTNRWFLTCINQPQFRAILGEVKLCEKMAQFDAKKFAE 223
           R+ F N NRWF T +NQP F+A+ G+V L +KMAQFDAKK+ +
Sbjct: 545 RKPFQNVNRWFTTLVNQPNFKAVAGDVTLAQKMAQFDAKKYGD 673
>20405
          Length = 766

 Score =  241 bits (616), Expect = 3e-64,   Method: Compositional matrix adjust.
 Identities = 119/220 (54%), Positives = 153/220 (69%), Gaps = 1/220 (0%)
 Frame = -1

Query: 5   TLYTYPENWRAFKALIAAQYSGAQVRVLSAPPHFHFGQTNRTPEFLRKFPAGKVPAFEGD 64
            LYTYPEN+RA+KALIAA+YSGA V+V    P+F FG+TN++  FL+KFPAGKVPA+E  
Sbjct: 766 VLYTYPENFRAYKALIAAKYSGADVKV---APNFVFGETNKSDGFLKKFPAGKVPAYESA 596

Query: 65  DGFCVF-ESNAIAYYVSNEELRGSTPEAAAQVVQWVSFADSDIVPPASTWVFPTLGIMHH 123
           DG  +  ESNAIAYYV+N  LRGS     A + QW S+ADS+++P +  WVFP LGIM  
Sbjct: 595 DGKVLLTESNAIAYYVANATLRGSDVATQAAIYQWASWADSELLPASCAWVFPYLGIMQF 416

Query: 124 NKQATENAKEEVKRILGLLDTHLKTRTFLVGERVTLADITVVCTLLWLYKQVLEPSFRQA 183
           NKQ  E AK ++   L +LD HL TRTFLV ER+TLADI V  TL+  ++ VL+ S R +
Sbjct: 415 NKQNVERAKNDLLAALKVLDGHLLTRTFLVTERITLADIIVFTTLIHAFQNVLDASIRSS 236

Query: 184 FPNTNRWFLTCINQPQFRAILGEVKLCEKMAQFDAKKFAE 223
             N  RWFLT  NQPQ  +++G + LCE    +D KK+ +
Sbjct: 235 LVNVQRWFLTLANQPQVASVVGNIVLCEAPPTYDPKKYQD 116
>20209
          Length = 979

 Score = 40.4 bits (93), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 40/155 (25%), Positives = 70/155 (45%), Gaps = 12/155 (7%)
 Frame = -1

Query: 48  EFLRKFPAGKVPAFEGDDGFCVFESNAIAYYVSN-----EELRGSTPEAAAQVVQWVSFA 102
           +F++  P   VPA   DDGF + ES AI  Y++      +    + P+  A+V +++ + 
Sbjct: 943 DFVKVHPFRLVPAL-NDDGFRLTESIAIVDYIAKTRDVADHWLPADPKKRAKVNEYLHWH 767

Query: 103 DSDIVPPASTWVFPTLGIMHH-------NKQATENAKEEVKRILGLLDTHLKTRTFLVGE 155
            ++    +S  +F  L ++          KQ     K     I G+ +  LK   F+  +
Sbjct: 766 HAN-TRLSSAMLFQHLLLIPRMKGEPVDQKQVKTFTKRVQTAIKGIENYFLKDTPFISSD 590

Query: 156 RVTLADITVVCTLLWLYKQVLEPSFRQAFPNTNRW 190
            +T+ADI  VC L+ LY  V +    ++ P    W
Sbjct: 589 VITVADIFAVCELMQLY-AVRQEELYESSPVVKAW 488
>37790
          Length = 428

 Score = 38.9 bits (89), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 20/36 (55%), Positives = 25/36 (69%)
 Frame = +1

Query: 402 LDPGSEETQTLVREYFSWEGTFQHVGKAVNQGKIFK 437
           LD  SEET+ LV +YFSW GT +  G+   +GKIFK
Sbjct: 4   LDAKSEETKKLVTQYFSWVGTDKD-GRKFKEGKIFK 108
>28739
          Length = 461

 Score = 30.0 bits (66), Expect = 1.7,   Method: Compositional matrix adjust.
 Identities = 15/26 (57%), Positives = 17/26 (65%)
 Frame = -2

Query: 139 LGLLDTHLKTRTFLVGERVTLADITV 164
           L  LD+ LK  TFLVG  +TLAD  V
Sbjct: 136 LDYLDSVLKPSTFLVGHALTLADFAV 59
>08076
          Length = 914

 Score = 29.3 bits (64), Expect = 3.2,   Method: Compositional matrix adjust.
 Identities = 20/67 (29%), Positives = 29/67 (43%)
 Frame = -2

Query: 124 NKQATENAKEEVKRILGLLDTHLKTRTFLVGERVTLADITVVCTLLWLYKQVLEPSFRQA 183
            KQ     K     I G+ +  LK   F+    +T+ADI  VC L+ LY  V +    ++
Sbjct: 778 QKQVKTFTKRVQTAIKGIENYFLKDTPFISSNVITVADIFAVCELMQLY-AVRQEELYES 602

Query: 184 FPNTNRW 190
            P    W
Sbjct: 601 SPVVKAW 581
>28559
          Length = 927

 Score = 27.7 bits (60), Expect = 9.7,   Method: Compositional matrix adjust.
 Identities = 12/32 (37%), Positives = 18/32 (56%)
 Frame = -3

Query: 175 VLEPSFRQAFPNTNRWFLTCINQPQFRAILGE 206
           +L+ +FR    N N W  + +N PQ  A+L E
Sbjct: 790 LLQETFRSHRQNPNFWVTSFVNHPQVSALLTE 695
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|29366814|ref|NP_083905.1| fumarylacetoacetate
hydrolase domain containing 2A [Mus musculus]
         (313 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

06673                                                                 288   2e-78
11431                                                                 108   2e-24
31401                                                                  97   8e-21
15967                                                                  29   2.5  
>06673
          Length = 4705

 Score =  288 bits (737), Expect = 2e-78,   Method: Compositional matrix adjust.
 Identities = 133/260 (51%), Positives = 182/260 (70%)
 Frame = -2

Query: 54   DLNAFDSTLPKTMVQFLEQGETTLSVARRALATQLPVIPRSQVTFLAPVTRPDKVICVGL 113
            D+   D T+P  M  F++ GE  L+ AR A+ +   V  R  V  LAP+T P+K++CVG+
Sbjct: 4674 DVTEVDPTVPHNMRDFIKGGEANLAAARSAIDSGHFVFKRENVKILAPITNPEKILCVGM 4495

Query: 114  NYADHCQEQNVRVXXXXXXXXXXXXXXVGPYDEIILPPESKEVDWEVEMAVVIGKKGKHI 173
            NY DHC+EQ   V              +GP D+++ P  ++++DWEVE+ +VIGK  +++
Sbjct: 4494 NYKDHCEEQGAPVPDEPVIFSKFNSAIIGPNDDLVYPQNTQQLDWEVELVIVIGKTARNV 4315

Query: 174  KATDVMAHVAGFTVAHDVSARDWQMRNGKQWLLGKTFDTFCPLGPALVTKDTIADPHNLK 233
                 M +V G+TVAHDVSARDWQ +NG Q+LLGKT D FCPLGPA+V K+ + DPH+LK
Sbjct: 4314 PVDKAMDYVFGYTVAHDVSARDWQFKNGGQFLLGKTIDGFCPLGPAIVMKEDLKDPHDLK 4135

Query: 234  ICCRVNGEVVQSSNTNQMVFKTEYLIAWVSQFVTLYPGDLLLTGTPPGVGMFRKPPVFLK 293
            +  RVN  V Q S+TNQ+VFKT  L+A++S+F+T+ PGD++LTGTPPGVG+FRKPP FLK
Sbjct: 4134 LYTRVNDVVKQDSSTNQLVFKTPELVAFISRFMTMKPGDIILTGTPPGVGVFRKPPEFLK 3955

Query: 294  KGDEVQCEIEELGVIINKVV 313
             GD V+ EIE +G +INKVV
Sbjct: 3954 VGDVVEVEIENIGKLINKVV 3895
>11431
          Length = 899

 Score =  108 bits (271), Expect = 2e-24,   Method: Compositional matrix adjust.
 Identities = 56/170 (32%), Positives = 90/170 (52%), Gaps = 3/170 (1%)
 Frame = +3

Query: 27  MRLVQFQAPHLEEPHLGLESXXXXXXXDLNAFDSTLPKTMVQFLEQGETTLSVARRALAT 86
           MR VQF+        +G+E        D+   D T+P  M  F++ GE  L+ AR A+ +
Sbjct: 123 MRFVQFEWNG--RLAVGVEKCDGGDIVDVTEVDPTVPHNMRDFIKGGEANLAAARSAIDS 296

Query: 87  QLPVIPRSQVTFLAPVTRPDKVICVGLNYADHCQEQNVRVXXXXXXXXXXXXXXVGPYDE 146
              V  R  V  LAP+T P+K++CVG+NY DHC+EQ   V              +GP D+
Sbjct: 297 GHFVFKRENVKILAPITNPEKILCVGMNYKDHCEEQGAPVPDEPVIFSKFNSAIIGPNDD 476

Query: 147 IILPPESKEVDWEVEMAVVIGKKGKHIKATD---VMAHVAGFTVAHDVSA 193
           ++ P  ++++DWEVE+ +VIGK  +++  +    ++ H+    V   VS+
Sbjct: 477 LVYPQNTQQLDWEVELVIVIGKTARNVPVSGSCFILVHLKKNHVVKSVSS 626
>31401
          Length = 647

 Score = 97.1 bits (240), Expect = 8e-21,   Method: Compositional matrix adjust.
 Identities = 50/124 (40%), Positives = 75/124 (60%), Gaps = 3/124 (2%)
 Frame = +2

Query: 185 FTVAHDVSARDWQ---MRNGKQWLLGKTFDTFCPLGPALVTKDTIADPHNLKICCRVNGE 241
           + +A D++ARD+Q    + G+ W L K FDT CP+    +  D + DP N+ +  +VNG 
Sbjct: 2   YILALDMTARDFQDEAKKKGQPWALAKGFDTSCPVS-GFIPFDKLQDPQNVALWLKVNGT 178

Query: 242 VVQSSNTNQMVFKTEYLIAWVSQFVTLYPGDLLLTGTPPGVGMFRKPPVFLKKGDEVQCE 301
           + Q  NT  M+F    LIA++SQ+ TL PGD++LTGTP GVG     P+    GD +QC 
Sbjct: 179 MKQEGNTKDMIFNIRTLIAFISQYFTLXPGDVILTGTPSGVG-----PIV--PGDTIQCG 337

Query: 302 IEEL 305
           + ++
Sbjct: 338 LADI 349
>15967
          Length = 794

 Score = 28.9 bits (63), Expect = 2.5,   Method: Compositional matrix adjust.
 Identities = 12/48 (25%), Positives = 23/48 (47%)
 Frame = +1

Query: 111 VGLNYADHCQEQNVRVXXXXXXXXXXXXXXVGPYDEIILPPESKEVDW 158
           +G++Y DH   + VR               +GPYDE++   + +++ W
Sbjct: 163 LGISYKDHITHEEVR---------RRIRHAIGPYDELLTTVKQRKLRW 279
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|50510465|dbj|BAD32218.1| mKIAA0373 protein [Mus
musculus]
         (1370 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

16375                                                                 255   2e-78
>16375
          Length = 1791

 Score =  255 bits (652), Expect(2) = 2e-78,   Method: Compositional matrix adjust.
 Identities = 166/429 (38%), Positives = 248/429 (57%), Gaps = 21/429 (4%)
 Frame = +3

Query: 233 AQKVINWHVKIEELRLQELKLNRELVKGKEEIKYLNNIISEYEHTINSLEEEIVQQSKFH 292
           A KV  WH K++ LRL+ELK  R   K  ++IKYL  II  +E +I+ LEE+ V+  K  
Sbjct: 3   ATKVAEWHSKMDALRLEELKQRRNNAKLHQQIKYLEEIIRSHEVSISELEEDNVRLLKGF 182

Query: 293 EERQMAWDQREVELERQLDIFDHQQNEILSPAQKFEDSTGSMPDPSLPLPNQLEIALRKI 352
           EERQM W+QRE ELER +   + Q  EI   A +FE + GS+PD  LP+ NQLE A+  I
Sbjct: 183 EERQMRWEQREGELERNILTMEKQTAEITGAAARFEQAIGSLPDAKLPVANQLEQAITTI 362

Query: 353 KENIQVILKTQATCXXXXXXXXXXXXXXXXXXQNILSRDKVINELRLRLPATADREKLI- 411
           K N++VIL TQA                    + ++ R+K+I+ELRLR+PAT DR+ +I 
Sbjct: 363 KTNVKVILDTQAENKAYKSKINEMEKLLKDSERTVIEREKLISELRLRMPATTDRDTIIE 542

Query: 412 ------AELERKELEP--KSHHTMKIAQQTIANMQARLTHKEEVLKKYQHLLERAREEQR 463
                 +E   K  EP  ++H  +KIAQ T+ ++Q R+  KEE + KYQ LL++AR++  
Sbjct: 543 RATAKVSEAMAKTSEPDYETHQGLKIAQSTVHSLQQRIQQKEETVVKYQELLKQARQDML 722

Query: 464 EIVKKHEEDLHVLHHKLEQQADNSLNKFRQTAQDLLKQSPA----PVPTNKHFIRLAEME 519
           ++ ++HE++L  + HK+ Q +D + +KF+Q AQ+LL Q       P  + K   RL E+E
Sbjct: 723 DMNRRHEQELKAMQHKVHQSSDIAFSKFKQAAQELLTQQSTTQRRPF-SEKQLERLTELE 899

Query: 520 QTVAEQXXXXXXXXXXXXXXXXXXEKQKEITELKVR--------EFENTKLRLQETHASE 571
            TVAEQ                   KQKE   +++R          +  K +L++  +S 
Sbjct: 900 DTVAEQENTIAALHEKI--------KQKEEDVIRLRAEIATSQKHIKTEKHKLKQEQSSL 1055

Query: 572 VKKVKAEVEDLRNALAQAHKDSQSLKSELQAQKEANSRAPTTTMRNLVDRLKSQLALKEK 631
             +   E++DL+  +    K+ + L  E+ A K++ +R PT +M+NLV+RLK QLALKEK
Sbjct: 1056QSQKNTELDDLQRVIGDQRKEIRVLNEEIDALKDSQARGPTASMKNLVERLKHQLALKEK 1235

Query: 632 QQKALSRAL 640
           Q ++LS+AL
Sbjct: 1236QHQSLSKAL 1262

 Score = 57.4 bits (137), Expect(2) = 2e-78,   Method: Compositional matrix adjust.
 Identities = 45/172 (26%), Positives = 86/172 (50%), Gaps = 3/172 (1%)
 Frame = +1

Query: 647  MTAAAEERIIAVTSQKEANLNVQQVVERHTRELKSQIEDXXXXXXXXXXXXXTSKNKENS 706
            M A A+  ++A   + +   NVQ++++  T++L  Q+ED               K  E+ 
Sbjct: 1282 MVAQAQNNVVAQAEEAQQERNVQRLIDASTKDLTEQLEDMQSQLERAKRELKKRKESESL 1461

Query: 707  LADDXXXXXXXXXXXXXAYNKILREKDGIDQENDELRRQIKRLSSGLQSKTLIDNKQSLI 766
            L  +             A+NK+   K  ++ E DEL ++++RLS+    KT    +   +
Sbjct: 1462 LQTELEDTKEELSRKERAHNKLRNSKAKLETEVDELEKKVERLSTHKSQKTADFERMQEL 1641

Query: 767  DELQKKVKKLESQLERKVDDVDIKPVKEKSSK---EELIRWEEGKKWQTKVE 815
            ++++++ + LE +L+++      KP ++K  K   EE +RWEE KKWQ  ++
Sbjct: 1642 EDMRRRNRYLEDELKKR--HTAEKPYEQKEDKTKTEEAMRWEESKKWQRTID 1791
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|94364569|ref|XP_996370.1| PREDICTED: Cdc42 binding
protein kinase alpha isoform 16 [Mus musculus]
         (1735 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

03240                                                                 291   2e-78
19704                                                                 127   7e-43
30755                                                                 134   3e-31
27590                                                                 125   1e-28
17932                                                                  86   2e-27
18484                                                                 100   2e-26
31885                                                                 115   2e-25
15910                                                                  97   6e-20
27405                                                                  97   7e-20
12721                                                                  95   3e-19
14420                                                                  94   4e-19
00300                                                                  92   2e-18
01707                                                                  91   3e-18
18921                                                                  88   3e-17
00486                                                                  86   2e-16
09606                                                                  85   3e-16
26560                                                                  85   3e-16
12786                                                                  84   4e-16
13592                                                                  84   7e-16
01392                                                                  83   1e-15
18663                                                                  76   1e-13
13212                                                                  75   3e-13
13066                                                                  72   2e-12
14126                                                                  71   4e-12
01060                                                                  70   7e-12
17975                                                                  67   8e-11
06405                                                                  66   1e-10
19094                                                                  65   3e-10
26156                                                                  64   5e-10
26711                                                                  64   8e-10
17722                                                                  64   8e-10
16708                                                                  62   2e-09
01718                                                                  61   4e-09
04591                                                                  60   8e-09
19761                                                                  59   1e-08
25445                                                                  59   2e-08
21079                                                                  57   6e-08
01966                                                                  57   7e-08
03508                                                                  56   1e-07
25019                                                                  56   1e-07
35187                                                                  56   2e-07
00715                                                                  55   2e-07
21433                                                                  55   3e-07
14116                                                                  55   3e-07
00392                                                                  55   4e-07
33586                                                                  54   7e-07
11185                                                                  54   8e-07
29581                                                                  52   2e-06
27546                                                                  51   4e-06
01756                                                                  51   4e-06
17591                                                                  37   1e-05
19361                                                                  48   4e-05
12672                                                                  47   6e-05
20152                                                                  47   8e-05
21808                                                                  47   8e-05
07836                                                                  45   2e-04
22804                                                                  45   2e-04
11353                                                                  45   2e-04
28638                                                                  45   3e-04
17300                                                                  45   3e-04
01431                                                                  43   9e-04
04852                                                                  42   0.001
29590                                                                  42   0.002
28157                                                                  41   0.003
27274                                                                  41   0.004
07833                                                                  41   0.004
32957                                                                  41   0.005
02638                                                                  41   0.005
37063                                                                  41   0.005
38560                                                                  40   0.007
09007                                                                  40   0.008
04138                                                                  40   0.009
37602                                                                  39   0.022
07291                                                                  39   0.024
18481                                                                  38   0.030
18996                                                                  38   0.031
19301                                                                  37   0.053
17516                                                                  37   0.068
31489                                                                  37   0.071
26009                                                                  37   0.072
20640                                                                  36   0.14 
15105                                                                  36   0.16 
00638                                                                  35   0.20 
07940                                                                  35   0.30 
11404                                                                  34   0.40 
18401                                                                  34   0.65 
11780                                                                  33   1.1  
12068                                                                  32   1.5  
30339                                                                  32   1.6  
01106                                                                  32   2.0  
31120                                                                  31   3.5  
24037                                                                  31   4.1  
29360                                                                  30   6.8  
>03240
          Length = 1683

 Score =  291 bits (744), Expect = 2e-78,   Method: Compositional matrix adjust.
 Identities = 152/362 (41%), Positives = 220/362 (60%), Gaps = 44/362 (12%)
 Frame = -3

Query: 66   KVKQMRLHREDFEILKVIGRGAFGEVAVVKLKNADKVFAMKILNKWEMLKRAETACFREE 125
            ++K+ ++ +  FE +K +G GAFGEV++ +  +   ++AMK L K ++LKR + A  + E
Sbjct: 1318 RLKRAKMDKCMFEKIKTLGVGAFGEVSLCRKNDTGMLYAMKTLRKSDVLKRNQVAHVKAE 1139

Query: 126  RDVLVNGDSKWITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSKFEDRLPEEMARFYLAEM 185
            RD+L   D++W+  L+Y+FQD N LY VMDY  GGDL+ LL + E  L E +ARFY+AE+
Sbjct: 1138 RDILAEADNEWVVKLYYSFQDHNYLYFVMDYVPGGDLMGLLIRMEI-LDEPLARFYVAEL 962

Query: 186  VIAIDSVHQLHYVHRDIKPDNILMDMNGHIRLADFGSCLKL---------MEDGT--VQS 234
            V AI+SVH++ ++HRDIKPDNIL+D NGHI+L DFG C              DGT   Q 
Sbjct: 961  VQAIESVHRMGFIHRDIKPDNILIDRNGHIKLTDFGLCTGFRWTHNSKYYQRDGTHARQD 782

Query: 235  SVA--------------------------------VGTPDYISPEILQAMEDGKGRYGPE 262
            S+                                 VGTP+YI+PE+L  +    G Y   
Sbjct: 781  SMEVKCQLDEQCQCEILKPLERRRKREQRCLAHSLVGTPNYIAPEVLSRL----GGYTSV 614

Query: 263  CDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKERFQFPAQVTDVSENAKDLIRRLI 322
            CDWWS+GV ++EML G  PFYA +  ET  K++N K+  + P + +++S+ AKDLI RL 
Sbjct: 613  CDWWSVGVILFEMLVGHPPFYANTPAETQYKVINWKDMLKIPRE-SNLSQPAKDLILRLC 437

Query: 323  CSREHRLGQNGIEDFKKHPFFSGIDWDNIRNCEAPYIPEVSSPTDTSNFD-VDDDCLKNS 381
            C  + RLG NG  + K H FF+G++++ +R  + PY+P +   TDTSNFD VD D L+NS
Sbjct: 436  CGSDDRLGLNGAGEIKTHMFFAGVNFETLRKQQPPYVPNIRYATDTSNFDPVDPDKLRNS 257

Query: 382  ET 383
            ++
Sbjct: 256  DS 251
>19704
          Length = 804

 Score =  127 bits (320), Expect(2) = 7e-43,   Method: Compositional matrix adjust.
 Identities = 69/176 (39%), Positives = 102/176 (57%), Gaps = 10/176 (5%)
 Frame = -1

Query: 1439 CQ--GRRSRQQELMWPANPSSCCYNAPYLSVYSENAVDIFDVNSMEWIQTLPLKKVRPLN 1496
            CQ  G RSR QE++WP+ P +  Y++PYL  Y+EN+  +F+V++ EW+QT+ LK+ +PL 
Sbjct: 588  CQETGERSRMQEILWPSQPIALSYSSPYLICYAENSTFVFNVDTAEWLQTMCLKRTKPLC 409

Query: 1497 TEGSLNLL-GLETIRLIYFKNKMAEGDELVVPETSDNSRKQMVRNINNKRRYSFRVPXXX 1555
              GSL LL  ++T  +I+ K    E D+L V E   N      ++  NKRR+SF+     
Sbjct: 408  KNGSLCLLSSVDTQHIIFLKTLHTEEDQLAVAEIFKN------KSSRNKRRFSFKSREDE 247

Query: 1556 XXXXXXXXXXDPE-------MRNKLISNPTNFNHIAHMGPGDGIQILKDLPMNPRP 1604
                        E        R+++IS P+NF+HIAHMGP  G+Q+L DLP   +P
Sbjct: 246  RSSNKRGDKALREKHGSVGDRRSRIISPPSNFSHIAHMGPDQGMQVLIDLPKQQKP 79

 Score = 66.6 bits (161), Expect(2) = 7e-43,   Method: Composition-based stats.
 Identities = 30/78 (38%), Positives = 50/78 (64%)
 Frame = -2

Query: 1365 VQWMAIFSEHLCVGFQSGFLRYPLNGEGGPCNMLHSNDHTLSFISHQPMDALCAVEISNK 1424
            VQ M +  E LCVG+ S F  Y + G+  P ++++++D TL F+   P++A+ AVE+++ 
Sbjct: 800  VQCMEMMGERLCVGYPSCFAIYSMQGDAPPLSLVNTDDRTLRFL-QTPVEAMLAVELASG 624

Query: 1425 EYLLCFNSIGIYTDCQGR 1442
            E+ L FN +G+Y   Q R
Sbjct: 623  EFXLLFNVVGLYVKKQER 570
>30755
          Length = 1137

 Score =  134 bits (337), Expect = 3e-31,   Method: Compositional matrix adjust.
 Identities = 79/222 (35%), Positives = 124/222 (55%), Gaps = 5/222 (2%)
 Frame = +2

Query: 175 EEMARFYLAEMVIAIDSVHQLHYVHRDIKPDNILMDMNGHIRLADFGSCLKLMEDGTVQS 234
           EE  RFY AE++ A+  +H    ++RD+K +N+L+D +GHI++ADFG C + +  G    
Sbjct: 29  EERTRFYGAEIISALGYLHSQGIIYRDLKLENLLLDKDGHIKVADFGLCKEDITYGRTTK 208

Query: 235 SVAVGTPDYISPEILQAMEDGKGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKI 294
           +   GTP+Y++PE+L   +     YG   DWW  GV MYEM+ G  PFY       +  I
Sbjct: 209 TFC-GTPEYLAPEVLDDND-----YGRAVDWWGTGVVMYEMICGRLPFYNRDHDVLFTLI 370

Query: 295 MNHKERFQFPAQVTDVSENAKDLIRRLIC-SREHRL--GQNGIEDFKKHPFFSGIDWDNI 351
           +   E  +FP  +TD    AK L+  L+     +RL  GQ+ +++ + HPFF+ I+W ++
Sbjct: 371 L--VEDVKFPRNITD---EAKSLLSGLLAKDPRNRLGGGQDDVKEIQAHPFFASINWTDL 535

Query: 352 --RNCEAPYIPEVSSPTDTSNFDVDDDCLKNSETMPPPTHTA 391
             +    P+ P+V+S TDT  F  D++    S  + PP  T 
Sbjct: 536 VQKKITPPFKPQVTSDTDTRYF--DEEFTGESVELTPPDPTG 655
>27590
          Length = 544

 Score =  125 bits (315), Expect = 1e-28,   Method: Compositional matrix adjust.
 Identities = 69/183 (37%), Positives = 104/183 (56%), Gaps = 6/183 (3%)
 Frame = -1

Query: 1435 IYTDCQGRRSRQQELMWPANPSSCCYNAPYLSVYSENAVDIFDVNSMEWIQTLPLKKVRP 1494
            +Y    G RSR QE++WP+ P +  Y +PYL  Y+EN+  +F+V + EW+QT+ LKK RP
Sbjct: 544  LYVKRSGERSRSQEILWPSQPLALSYCSPYLVCYAENSTFVFNVQTAEWLQTMCLKKTRP 365

Query: 1495 LNTEGSLNLL-GLETIRLIYFKNKMAEGDELVVPETSDNSRKQMVRNINNKRRYSFRVPX 1553
            L  +GSL LL   +T  +I+ KN  A+ D L V E       +  R  + K +   R   
Sbjct: 364  LCKDGSLCLLSAFDTQHVIFLKNLHADEDRLAVAEIFRXRNSRSKRRFSFKSKEDER--- 194

Query: 1554 XXXXXXXXXXXXDPEMRNKLISNPTNFNHIAHMGPGDGIQILKDLPM-----NPRPQESR 1608
                          + R+++ISNP+NF+HIAHMGP  G+Q+L DLP      +P+ Q+ +
Sbjct: 193  ---------SGSKGDRRSRVISNPSNFSHIAHMGPDQGMQVLIDLPKQQAEGDPQLQKVK 41

Query: 1609 TVF 1611
            ++F
Sbjct: 40   SMF 32
>17932
          Length = 597

 Score = 86.3 bits (212), Expect(2) = 2e-27,   Method: Composition-based stats.
 Identities = 43/99 (43%), Positives = 61/99 (61%), Gaps = 2/99 (2%)
 Frame = -3

Query: 308 TDVSENAKDLIRRLICSREHRLGQNGIEDFKKHPFFSGIDWDNIRNCEAPYIPEVSSPTD 367
           + VS+ A+DLI +L+   + RLG     + ++HPFF  +DW NIRN   PY+P +SS  D
Sbjct: 466 SSVSKEARDLISQLLSDGKSRLGW---PELQQHPFFKTVDWANIRNAMPPYVPSISSLDD 296

Query: 368 TSNFDVDDDC--LKNSETMPPPTHTAFSGHHLPFVGFTY 404
           TS+FD  +      N ++   P+   F+G HLPFVGFTY
Sbjct: 295 TSHFDEVEKARPAPNIDSFHQPSSRDFTGRHLPFVGFTY 179

 Score = 56.6 bits (135), Expect(2) = 2e-27,   Method: Composition-based stats.
 Identities = 25/44 (56%), Positives = 30/44 (68%), Gaps = 2/44 (4%)
 Frame = -2

Query: 265 WWSLGVCMYEMLYGETPFYAE--SLVETYGKIMNHKERFQFPAQ 306
           WWSLGVC YEML+G TPF  +  S+V TY  IMN+K     P+Q
Sbjct: 596 WWSLGVCAYEMLFGCTPFTDDDGSMVATYNNIMNYKTNSSSPSQ 465
>18484
          Length = 635

 Score =  100 bits (250), Expect(2) = 2e-26,   Method: Compositional matrix adjust.
 Identities = 49/132 (37%), Positives = 74/132 (56%)
 Frame = +1

Query: 170 EDRLPEEMARFYLAEMVIAIDSVHQLHYVHRDIKPDNILMDMNGHIRLADFGSCLKLMED 229
           E +  E +A FY AE+ + +  +H    ++RD+K DN+++D  GHI++ADFG C + M  
Sbjct: 25  EGKFKEPVAAFYAAEIAVGLFFLHDQGIIYRDLKLDNVMLDSEGHIKIADFGMCKEGMT- 201

Query: 230 GTVQSSVAVGTPDYISPEILQAMEDGKGRYGPECDWWSLGVCMYEMLYGETPFYAESLVE 289
           G   +    GTPDYI+PEI+         Y    DWW+ GV ++EML G+ PF  E   E
Sbjct: 202 GDATTRTFCGTPDYIAPEIVLYQP-----YSKSVDWWAYGVLLFEMLAGQPPFDGEDEDE 366

Query: 290 TYGKIMNHKERF 301
            +  I +H   +
Sbjct: 367 LFSSITDHNVSY 402

 Score = 38.1 bits (87), Expect(2) = 2e-26,   Method: Composition-based stats.
 Identities = 18/44 (40%), Positives = 24/44 (54%), Gaps = 2/44 (4%)
 Frame = +2

Query: 331 QNGIEDFKKHPFFSGIDWDNIRNCEA--PYIPEVSSPTDTSNFD 372
           QNG  D + H FF  I WD I++ E   PY P+++      NFD
Sbjct: 485 QNGERDIRDHAFFRRIVWDKIKSMEVQPPYKPKITDRRKAENFD 616
>31885
          Length = 529

 Score =  115 bits (288), Expect = 2e-25,   Method: Compositional matrix adjust.
 Identities = 61/160 (38%), Positives = 94/160 (58%)
 Frame = -2

Query: 127 DVLVNGDSKWITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSKFEDRLPEEMARFYLAEMV 186
           D+L   D  ++  L YAFQD+ +L++V+D ++GGDL   + + E    E+  +FYL ++ 
Sbjct: 516 DMLTRLDHPFLVNLWYAFQDEEDLFMVVDLFLGGDLRYHMQQ-EVSFREDCVKFYLCQLA 340

Query: 187 IAIDSVHQLHYVHRDIKPDNILMDMNGHIRLADFGSCLKLMEDGTVQSSVAVGTPDYISP 246
           + +D +     VHRDIKPDNIL+D  GH  + DF    +L ED  + +S + GT  Y++P
Sbjct: 339 LVLDYLRSQKIVHRDIKPDNILLDEQGHCHVTDFNIATQL-EDDELATSTS-GTRPYMAP 166

Query: 247 EILQAMEDGKGRYGPECDWWSLGVCMYEMLYGETPFYAES 286
           E+     + +  YG   DWWSLGV ++E+L    PF   S
Sbjct: 165 EVYGVAINERRGYGFPVDWWSLGVSLFELLKKRRPFSVHS 46
>15910
          Length = 1361

 Score = 97.1 bits (240), Expect = 6e-20,   Method: Compositional matrix adjust.
 Identities = 53/144 (36%), Positives = 86/144 (59%), Gaps = 3/144 (2%)
 Frame = +2

Query: 182 LAEMVIAIDSVHQLHYVHRDIKPDNIL---MDMNGHIRLADFGSCLKLMEDGTVQSSVAV 238
           +++++  +  +H    VHRD+KP+N+L   M  +  ++LADFG  L  + +  VQ S   
Sbjct: 482 ISDILHGVQYIHANGVVHRDLKPENLLYECMTDDSKLKLADFG--LSRIIEPEVQMSTVC 655

Query: 239 GTPDYISPEILQAMEDGKGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHK 298
           GTP Y +PE+L+       +Y P  D WS+GV  Y +L G  PF+AE+  E Y KI+  +
Sbjct: 656 GTPGYCAPEVLKG-----DKYTPSVDMWSVGVIAYILLCGYEPFFAENEFEMYRKIIKGE 820

Query: 299 ERFQFPAQVTDVSENAKDLIRRLI 322
            +F      +++SENAKD++R+L+
Sbjct: 821 YKFD-EEYWSEISENAKDVVRKLL 889
>27405
          Length = 532

 Score = 96.7 bits (239), Expect = 7e-20,   Method: Compositional matrix adjust.
 Identities = 63/185 (34%), Positives = 99/185 (53%), Gaps = 5/185 (2%)
 Frame = -3

Query: 87  AFGEVAVVKLKNADKVFAMKILNKWEM-LKRAETACFREE--RDVLVNGD-SKWITTLHY 142
            FGEV   +  +  K++AMK L+K  + +K  ET    E     ++  G+ S +I  + Y
Sbjct: 530 GFGEVYGCRKADTGKMYAMKCLDKKRIKMKGGETLALNERIMLSLVSTGEGSPFIVCMTY 351

Query: 143 AFQDDNNLYLVMDYYVGGDLLTLLSKFEDRLPEEMARFYLAEMVIAIDSVHQLHYVHRDI 202
           AFQ    L  ++D   GGDL   LS+      E+  RFY AE+++ ++ +H    V+RD+
Sbjct: 350 AFQTPEKLCFILDLMNGGDLHYHLSQ-HGVFTEKEVRFYAAEVMLGLEHMHSRFVVYRDL 174

Query: 203 KPDNILMDMNGHIRLADFGSCLKLMEDGTVQSSVAVGTPDYISPEILQAMEDGKGR-YGP 261
           KP NIL+D NGH+R++D G      +    +   +VGT  Y++PE+L      KG+ Y  
Sbjct: 173 KPANILLDENGHVRISDLGLACDFSKK---KPHASVGTHGYMAPEVLM-----KGQAYDS 18

Query: 262 ECDWW 266
             DW+
Sbjct: 17  SADWF 3
>12721
          Length = 821

 Score = 94.7 bits (234), Expect = 3e-19,   Method: Compositional matrix adjust.
 Identities = 58/212 (27%), Positives = 112/212 (52%)
 Frame = +1

Query: 83  IGRGAFGEVAVVKLKNADKVFAMKILNKWEMLKRAETACFREERDVLVNGDSKWITTLHY 142
           IG G+ G V +   ++  ++     + K ++ K+        E  V+ +     I  ++ 
Sbjct: 112 IGEGSTGIVCIATSRDGRQM----AVKKMDLRKQQRRELLFNEVVVMRDYHHPNIVEMYN 279

Query: 143 AFQDDNNLYLVMDYYVGGDLLTLLSKFEDRLPEEMARFYLAEMVIAIDSVHQLHYVHRDI 202
           ++  ++ L++VM++  GG L  +++   +R+ E          + A+  +H    +HRDI
Sbjct: 280 SYLVNDELWVVMEFMEGGALTDIVTN--NRMDEVQIATVCRACLKALAFLHANGVIHRDI 453

Query: 203 KPDNILMDMNGHIRLADFGSCLKLMEDGTVQSSVAVGTPDYISPEILQAMEDGKGRYGPE 262
           K D+IL+  +G ++L DFG C ++ +D   + S+ VGTP +++PE++  +      YGPE
Sbjct: 454 KSDSILLSHDGKVKLXDFGFCAQVTQDLQKRKSL-VGTPYWMAPEVISRLP-----YGPE 615

Query: 263 CDWWSLGVCMYEMLYGETPFYAESLVETYGKI 294
            D WSLG+ + EM+  E PF+ E  ++   +I
Sbjct: 616 VDIWSLGIMVMEMIDAEPPFFNEPPLQAMRRI 711
>14420
          Length = 528

 Score = 94.0 bits (232), Expect = 4e-19,   Method: Compositional matrix adjust.
 Identities = 50/137 (36%), Positives = 84/137 (61%)
 Frame = +2

Query: 150 LYLVMDYYVGGDLLTLLSKFEDRLPEEMARFYLAEMVIAIDSVHQLHYVHRDIKPDNILM 209
           L++VM++  GG L  +++  E  + E        E + A++ +H+   +HRDIK DNIL+
Sbjct: 125 LWVVMEFLAGGSLTDVVT--ETCMDEGQIAAVCRECLQALEFLHENQVIHRDIKSDNILL 298

Query: 210 DMNGHIRLADFGSCLKLMEDGTVQSSVAVGTPDYISPEILQAMEDGKGRYGPECDWWSLG 269
            M+G ++L DFG C +L  + + +S++ VGTP +++PE++      + +YGP  D WSLG
Sbjct: 299 GMDGSVKLTDFGFCAQLSPEQSKRSTM-VGTPYWMAPEVVT-----RKQYGPTVDIWSLG 460

Query: 270 VCMYEMLYGETPFYAES 286
           V   EM+ GE P+  E+
Sbjct: 461 VMCIEMIEGEPPYLNEN 511
>00300
          Length = 2318

 Score = 91.7 bits (226), Expect = 2e-18,   Method: Compositional matrix adjust.
 Identities = 69/244 (28%), Positives = 116/244 (47%), Gaps = 3/244 (1%)
 Frame = -1

Query: 83   IGRGAFGEVAVVKLKNADKVFAMKILN-KWEMLKRAETACFREERDVLVNGDSKWITTLH 141
            IG G FG+V      +  ++ A+K +  +   L++    C  +E  +      + +   +
Sbjct: 1634 IGEGQFGKVYTAVNMSTGELMALKEMKFQPNDLQQLREMC--DEIKIFEGIQHENLVKYY 1461

Query: 142  YAFQDDNNLYLVMDYYVGGDLLTLLSKFEDRLPEEMARFYLAEMVIAIDSVHQLHYVHRD 201
                  + + + M+Y    D  T+    +  LPE + R Y  E+V+A++ +H+   VHRD
Sbjct: 1460 GVEVHKDEMLMFMEYC---DTGTIEEAAKMGLPEYLIRRYTREIVLAVNHLHENSIVHRD 1290

Query: 202  IKPDNILMDMNGHIRLADFGSCLKLMEDGTVQSSV--AVGTPDYISPEILQAMEDGKGRY 259
            IK  NI +  NGH++L DFG  +KL    T+       VGT  Y++PE+    ++ +G Y
Sbjct: 1289 IKGANIFLTSNGHVKLGDFGCSVKLKSHTTMPGEFHNLVGTTAYMAPEVF--TQNDQGGY 1116

Query: 260  GPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKERFQFPAQVTDVSENAKDLIR 319
            G   D WSLG  + EM  G+ P++   L   Y +IM        PA    +S   K  + 
Sbjct: 1115 GRAADIWSLGCVVIEMATGKRPWH--DLDNNY-QIMYKVGIGHKPAVPDSLSVEGKHFLD 945

Query: 320  RLIC 323
             ++C
Sbjct: 944  LIMC 933
>01707
          Length = 757

 Score = 91.3 bits (225), Expect = 3e-18,   Method: Compositional matrix adjust.
 Identities = 66/215 (30%), Positives = 107/215 (49%)
 Frame = +1

Query: 75  EDFEILKVIGRGAFGEVAVVKLKNADKVFAMKILNKWEMLKRAETACFREERDVLVNGDS 134
           E +E +  IG G++G V   + K   ++ A+K   + E     +    RE R +L     
Sbjct: 64  EKYEKIGKIGEGSYGVVFKCRNKETSQLVAIKKFVESEDDPLIKKIAMREIR-MLKQLKH 240

Query: 135 KWITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSKFEDRLPEEMARFYLAEMVIAIDSVHQ 194
             +  L   F+    L+LV DY V   LL  L ++   LPE M +  + + ++A++  HQ
Sbjct: 241 PNLVRLIEVFRRKKRLHLVFDY-VDHTLLNELDRYPRGLPEPMVKRIIYQTLLAVNFCHQ 417

Query: 195 LHYVHRDIKPDNILMDMNGHIRLADFGSCLKLMEDGTVQSSVAVGTPDYISPEILQAMED 254
            + +HRD+KP+NIL+   G ++L DFG    L   G  + +  V T  Y +PE+L     
Sbjct: 418 YNTIHRDVKPENILITRQGQVKLCDFGFARILTGPGD-EYTDYVATRWYRAPELLV---- 582

Query: 255 GKGRYGPECDWWSLGVCMYEMLYGETPFYAESLVE 289
           G  +YGP  D W++G    E+L G+  +   S V+
Sbjct: 583 GDTQYGPPVDVWAIGCVFAELLTGQALWPGRSDVD 687
>18921
          Length = 697

 Score = 88.2 bits (217), Expect = 3e-17,   Method: Compositional matrix adjust.
 Identities = 60/214 (28%), Positives = 106/214 (49%), Gaps = 2/214 (0%)
 Frame = +2

Query: 77  FEILKVIGRGAFGEVAVVKLKNADKVFAMKILNKWEMLKRAETACFREERDVLVNGDSKW 136
           F+IL  +G G++G V     K   +V A+K     ++    +     +E  ++   DSK+
Sbjct: 35  FDILGKLGEGSYGSVFKSLHKETGQVLAIK-----QVPVDTDLQEIIKEISIMQQCDSKY 199

Query: 137 ITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSKFEDRLPEEMARFYLAEMVIAIDSVHQLH 196
           I   + ++  + +L++VM+Y   G +  ++      L E      L   +  +  +H   
Sbjct: 200 IVKYYGSYFKNTDLWIVMEYCGAGSVSDIMRLRNKTLVEREIATILYYTLKGLXYLHSRR 379

Query: 197 YVHRDIKPDNILMDMNGHIRLADFGSCLKLMEDGTVQSSVAVGTPDYISPEILQAMEDGK 256
            +HRDIK  NIL++  GH +LADFG   +L  D   + +  +GTP +++PE++Q +    
Sbjct: 380 KIHRDIKAGNILLNNEGHAKLADFGVAGQL-TDTMAKRNTVIGTPYWMAPEVIQEI---- 544

Query: 257 GRYGPEC--DWWSLGVCMYEMLYGETPFYAESLV 288
              G +C  D WSLG+   EM  G+ P    S++
Sbjct: 545 ---GYDCVADIWSLGITALEMAEGKPPVMETSIL 637
>00486
          Length = 797

 Score = 85.5 bits (210), Expect = 2e-16,   Method: Compositional matrix adjust.
 Identities = 65/179 (36%), Positives = 88/179 (49%), Gaps = 7/179 (3%)
 Frame = -2

Query: 239 GTPDYISPEILQAMEDGKGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHK 298
           GT +Y++PEIL     GK       DWWSLG  MY+ML G  PF AE+  +T  KI+  K
Sbjct: 772 GTIEYMAPEILTRTGHGKA-----VDWWSLGALMYDMLTGSPPFTAENRKKTIDKIL--K 614

Query: 299 ERFQFPAQVTDVSENAKDLIRRLI-CSREHRLGQNGIED---FKKHPFFSGIDWD--NIR 352
            +   P  +T+    A+ LI++L+  +   RLG  G +D    K H FF   +W    +R
Sbjct: 613 GKLNLPPYLTN---EARGLIKKLLRKNPAERLG-GGHDDSGPIKDHQFFRNTNWALLALR 446

Query: 353 NCEAPYIPEVSSPTDTSNFDVDDDCLKNSETMPPPTHTAFSGH-HLPFVGFTYTSSCVL 410
             E P+ P V+S  DTS FD           +  P  T  S   +  F GFTY +  VL
Sbjct: 445 RAEPPFRPNVTSDEDTSQFDTK---FTRQTPVDSPDDTILSDSINQVFKGFTYIAPSVL 278
>09606
          Length = 1300

 Score = 84.7 bits (208), Expect = 3e-16,   Method: Compositional matrix adjust.
 Identities = 64/244 (26%), Positives = 108/244 (44%), Gaps = 22/244 (9%)
 Frame = -3

Query: 75   EDFEILKVIGRGAFGEVAVVKLKNADKVFAMKILNKWEMLKRAE-TACFREERDVLVNGD 133
            E+F + + +G+G    +   + K      A+  + K    KR E T   R   D+     
Sbjct: 1115 ENFVLYEELGKGEHSIIYKGRRKGTINFVAIHCIEK---CKRPEVTNTVRMTHDI----S 957

Query: 134  SKWITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSKFEDRLPEEMARFYLAEMVIAIDSVH 193
               +   H  ++  N+L+LV++   GG L  +L++ +  LPE   R +   +V  +  +H
Sbjct: 956  HPNVVQFHEWYETSNHLWLVVELCTGGSLADILAQ-DHHLPETSIRDFGIHLVTGLHYIH 780

Query: 194  QLHYVHRDIKPDNILMDMNGHIRLADFGSC-----------LKLMEDG---TVQSSVAV- 238
             L  +  D++P  +L+D +G ++ ADFG              K  E G    +QS+  + 
Sbjct: 779  SLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEAGDQWNIQSAEEMM 600

Query: 239  ------GTPDYISPEILQAMEDGKGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYG 292
                  G+P Y++PE+ Q  E          D W+LG   YEM  G  PF  E+   T  
Sbjct: 599  KQVPTSGSPTYMAPEVFQGAEPSI-----MSDLWALGCVFYEMFSGHPPFLGETYDITKD 435

Query: 293  KIMN 296
            K++N
Sbjct: 434  KVLN 423
>26560
          Length = 398

 Score = 84.7 bits (208), Expect = 3e-16,   Method: Composition-based stats.
 Identities = 41/109 (37%), Positives = 66/109 (60%), Gaps = 1/109 (0%)
 Frame = -1

Query: 175 EEMARFYLAEMVIAIDSVHQLHYVHRDIKPDNILMDMNGHIRLADFGSCLKLMEDGTVQS 234
           E+  RFY AE+++ ++ +H    V+RD+KP NIL+D NGH+R++D G      +    + 
Sbjct: 359 EKEVRFYAAEVMLGLEHMHSRFVVYRDLKPANILLDENGHVRISDLGLACDFSKK---RP 189

Query: 235 SVAVGTPDYISPEILQAMEDGKGR-YGPECDWWSLGVCMYEMLYGETPF 282
             +VGT  Y++PE+L      KG+ Y    DW+S G  +Y++L G +PF
Sbjct: 188 HASVGTHGYMAPEVLM-----KGQSYDSSADWFSFGCMLYKLLKGHSPF 57
>12786
          Length = 460

 Score = 84.0 bits (206), Expect = 4e-16,   Method: Compositional matrix adjust.
 Identities = 50/132 (37%), Positives = 70/132 (53%), Gaps = 16/132 (12%)
 Frame = -3

Query: 167 SKFEDRLPEEMARFYLAEMVIAIDSVHQLHYVHRDIKPDNILMDMNGHIRLADFGSCLKL 226
           +K E  L   M +FY  EM+ A+ ++H    +H D+KP N ++ + G+++L DFG    L
Sbjct: 437 AKQEQGLDRMMIKFYWREMLRAVKALHNEGVIHSDLKPANFML-VAGNLKLIDFGIANTL 261

Query: 227 MEDGT-VQSSVAVGTPDYISPEILQAM----------EDG-----KGRYGPECDWWSLGV 270
            +D T V     VGTP Y+SPE + A           EDG     K + G   D WSLG 
Sbjct: 260 QQDKTSVLKDSRVGTPSYMSPEAIMAACDDSADDSMEEDGHRTKPKYKVGVRSDVWSLGC 81

Query: 271 CMYEMLYGETPF 282
            +Y M+YG TPF
Sbjct: 80  ILYNMVYGRTPF 45
>13592
          Length = 980

 Score = 83.6 bits (205), Expect = 7e-16,   Method: Compositional matrix adjust.
 Identities = 63/207 (30%), Positives = 103/207 (49%), Gaps = 7/207 (3%)
 Frame = +2

Query: 83  IGRGAFGEVAVVKLKNADKVFAMKILNKWEMLKRAETACFR---EERDVLVNGDSKWITT 139
           IG+G FG+V      N  ++ AMK +     ++  ET   +   EE  +L     K +  
Sbjct: 8   IGQGRFGKVYTAVNNNTGELMAMKEI----AIQPGETRALKNVAEELKILEGIKHKNLVR 175

Query: 140 LHYAFQDDNNLYLVMDYYVGGDLLTLLSKFEDRLPEEMARFYLAEMVIAIDSVHQLHYVH 199
            +        L + M+    G L +L+ +    LPE ++R + A+++  +  +H+   VH
Sbjct: 176 YYGIEVHREELLIFMELCSEGTLESLV-ELTGGLPEALSRRFTAQLLSGVAELHKHGIVH 352

Query: 200 RDIKPDNI-LMDMNGHIRLADFGSCLKLMEDGTVQSSVA--VGTPDYISPEIL-QAMEDG 255
           RDIK  NI L+D +  ++L DFGS +K+    TV   +   VGT  Y++PE+  +   DG
Sbjct: 353 RDIKTANIFLVDGSNSLKLGDFGSAVKIQAHTTVPGELQGYVGTQAYMAPEVFTKTNSDG 532

Query: 256 KGRYGPECDWWSLGVCMYEMLYGETPF 282
            GR     D WS+G  + EM  G+ P+
Sbjct: 533 HGRL---ADIWSVGCVVVEMASGKRPW 604
>01392
          Length = 1806

 Score = 82.8 bits (203), Expect = 1e-15,   Method: Compositional matrix adjust.
 Identities = 65/215 (30%), Positives = 101/215 (46%), Gaps = 21/215 (9%)
 Frame = -1

Query: 172  RLPEEMARFYLAEMVIAIDSVHQLHYVHRDIKPDNIL---MDMNGHIRLADF--GSCLKL 226
             L E  A   +  +  A+D +H     HRD+KP+NIL   +D    +++ DF   S +  
Sbjct: 1803 HLCEREASLVVRHIARALDFLHSKGIAHRDLKPENILCEHLDDVVPVKICDFDLASGISC 1624

Query: 227  MEDGTVQSSV--AVGTPDYISPEILQAMEDGKGRYGPECDWWSLGVCMYEMLYGETPFY- 283
              DGT    +   VG+ +Y++PE++ A       Y   CD WSLG+ +Y ML G  PFY 
Sbjct: 1623 DGDGTKTPELLTPVGSAEYMAPEVVDAWVGDSFSYDKRCDLWSLGIILYIMLCGYPPFYG 1444

Query: 284  ----------AESLVETYGKIMNHKE--RFQFPAQ-VTDVSENAKDLIRRLICSREHRLG 330
                       E+  +    + N  +   ++FP+Q  T +S +AKDLIR L+  RE R  
Sbjct: 1443 QCGEDCGWNRGEACHDCQDMLFNSIQDGHYKFPSQEWTSISSSAKDLIRHLL-VREPR-K 1270

Query: 331  QNGIEDFKKHPFFSGIDWDNIRNCEAPYIPEVSSP 365
            +    D  KHP+           C  P   ++++P
Sbjct: 1269 RYSAADVLKHPWI----------CTPPAATQLATP 1195
>18663
          Length = 600

 Score = 75.9 bits (185), Expect = 1e-13,   Method: Compositional matrix adjust.
 Identities = 59/197 (29%), Positives = 90/197 (45%), Gaps = 15/197 (7%)
 Frame = +2

Query: 235 SVAVGTPDYISPEILQAMEDGKGRYGPECDWWSLGVCMYEMLYGETPF-------YAESL 287
           S   GTP+YI+PEIL+  ED    YG   DWW+LGV +YEML G +PF         +  
Sbjct: 2   STFCGTPNYIAPEILRG-ED----YGFSVDWWALGVLLYEMLAGRSPFDIAGASENPDQN 166

Query: 288 VETYGKIMNHKERFQFPAQVTDVSENA------KDLIRRLICSREHRLGQNGIEDFKKHP 341
            E Y   +  ++  + P  ++  + +       K+   RL C RE     +   D   HP
Sbjct: 167 TEDYLFQVILEKTIRIPRSLSVKAASVLKGFLNKNPADRLGCHRE-----SAFMDIVNHP 331

Query: 342 FFSGIDWDNI--RNCEAPYIPEVSSPTDTSNFDVDDDCLKNSETMPPPTHTAFSGHHLPF 399
           FF  IDW+ +  +    P+ P + S  D +NF ++    +  +  P   H   S     F
Sbjct: 332 FFKVIDWEMLERKQVSPPFKPRLDSDRDLANFPIEFTG-EPVQLTPDDDHVIDSIDQSEF 508

Query: 400 VGFTYTSSCVLSDRSCL 416
            GF Y +  ++S   C+
Sbjct: 509 EGFEYVNPLLMSLEDCV 559
>13212
          Length = 1067

 Score = 74.7 bits (182), Expect = 3e-13,   Method: Compositional matrix adjust.
 Identities = 40/135 (29%), Positives = 72/135 (53%), Gaps = 3/135 (2%)
 Frame = -1

Query: 150  LYLVMDYY---VGGDLLTLLSKFEDRLPEEMARFYLAEMVIAIDSVHQLHYVHRDIKPDN 206
            ++ ++D +     G L +++   E  + E    +   EM +A+D +H+ H +HRDIK  N
Sbjct: 1067 VWXIVDVFRVLWWGALDSIMVDLEKPMTEAQICYVCHEMCMALDFLHRHHVIHRDIKAGN 888

Query: 207  ILMDMNGHIRLADFGSCLKLMEDGTVQSSVAVGTPDYISPEILQAMEDGKGRYGPECDWW 266
            +L+ ++G ++LADFG   K  +    + +  +GTP +++PE++         Y  + D W
Sbjct: 887  VLLTIDGEVKLADFGVSAKNTQTQQKRDTF-IGTPYWMAPEVVLCETLKDTPYDFKADIW 711

Query: 267  SLGVCMYEMLYGETP 281
            SLGV + E    E P
Sbjct: 710  SLGVTLIEFAQIEPP 666
>13066
          Length = 551

 Score = 72.0 bits (175), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 47/151 (31%), Positives = 76/151 (50%), Gaps = 3/151 (1%)
 Frame = +3

Query: 122 FREERDVLVNGDSKWITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSKFEDRLPEEMARFY 181
           F  E D+L   D  +I  +H   Q     ++ M +   GDLLT + +    + E+ A+ +
Sbjct: 117 FPRELDLLTKLDHPYIIQIHSILQRXPKNFIFMRFAERGDLLTYIQEV-GFVKEKQAKIW 293

Query: 182 LAEMVIAIDSVHQLHYVHRDIKPDNILMDMNGHIRLADFG-SCLKLMEDG-TVQSSVAVG 239
             +M  A++ +H     HRD+K +NIL+  + +++LADFG +C  + E G    S    G
Sbjct: 294 FYQMTTALNYLHSYDVAHRDLKCENILLSSHFNVKLADFGFACACITESGEKYMSRTYCG 473

Query: 240 TPDYISPEILQAMEDGKGRYGPE-CDWWSLG 269
           +  Y +PEI+         Y P+  D WSLG
Sbjct: 474 SAAYAAPEIVYG-----APYAPKVADAWSLG 551
>14126
          Length = 1265

 Score = 70.9 bits (172), Expect = 4e-12,   Method: Compositional matrix adjust.
 Identities = 82/313 (26%), Positives = 133/313 (42%), Gaps = 31/313 (9%)
 Frame = +3

Query: 75  EDFEILKVIGRGAFGEVAVVK-LKNADKVFAMKI--LNKWE----MLKRAETACFREERD 127
           + +E + VIG GA+G V   + L+N  +  AMK   LN  E    M+   E +  ++   
Sbjct: 189 QKYEEVAVIGNGAYGTVYKARDLRNQGEFVAMKRIRLNNTEEGMPMMAIREISMLKQLEQ 368

Query: 128 VLVNGDSKWITTLHYAFQD-DNNLYLVMDYYVGGDLLTLLSKFED-RLPEEMARFYLAEM 185
                  + +   H    D +  L LV +Y +  DL T L+K     L  +  +  + ++
Sbjct: 369 YEHPNVVRLLDVSHNTITDREIRLNLVFEY-IEHDLATYLAKCPSPGLGPDRIKDLMLQL 545

Query: 186 VIAIDSVHQLHYVHRDIKPDNILMDMNGHIRLADFGSCLKLMEDGTVQSSVAVGTPDYIS 245
           +  +D +H    VHRD+KP N+L+  +G ++LADFG  L  +    +  +  V T  Y S
Sbjct: 546 LNGVDFLHSNRIVHRDLKPQNLLISKDGRLKLADFG--LARIYSFHMALTTVVVTLWYRS 719

Query: 246 PEILQAMEDGKGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMN--------- 296
           PE+L   E     YG   D WS G    E+      F   S  +   KI           
Sbjct: 720 PEVLMQAE-----YGTSVDIWSCGCIFAELFTRRALFKGSSEFDQLKKIFEVIGLPPAGD 884

Query: 297 -------HKERFQ----FPAQ--VTDVSENAKDLIRRLICSREHRLGQNGIEDFKKHPFF 343
                  H+  F+     P Q  V ++   AKDL+ +++  +  R  +    +   HP+ 
Sbjct: 885 WPEGVSVHRNSFRPTPPVPLQTLVPEMDPQAKDLMEKMLVFKSGR--RISSRESLLHPYL 1058

Query: 344 SGIDWDNIRNCEA 356
              D D+IR   +
Sbjct: 1059RD-DLDSIRTSSS 1094
>01060
          Length = 1800

 Score = 70.1 bits (170), Expect = 7e-12,   Method: Compositional matrix adjust.
 Identities = 60/215 (27%), Positives = 95/215 (44%), Gaps = 2/215 (0%)
 Frame = +1

Query: 83  IGRGAFGEVAVVKLKNADKVFAMKILNKWEMLKRAETACFREERDVLVNGDSKWITTLHY 142
           IG G +G V   + +   +  AMK +          ++  RE   +L       I  L  
Sbjct: 97  IGEGTYGVVYKCRHRATGRKLAMKKIRLRGSEDGVPSSAIREIA-MLRELRHTNIVCLED 273

Query: 143 AFQDDNNLYLVMDYYVGGDLLTLLSKFEDR--LPEEMARFYLAEMVIAIDSVHQLHYVHR 200
              +D  L+LV ++ +  DL   + KF +   L   + + Y+ ++V  I   HQ   VHR
Sbjct: 274 VIMEDERLFLVFEF-LSMDLKMYIDKFPEGVVLDRRLVKSYVFQIVTGIXFCHQRRIVHR 450

Query: 201 DIKPDNILMDMNGHIRLADFGSCLKLMEDGTVQSSVAVGTPDYISPEILQAMEDGKGRYG 260
           D+KP N+L++  G I++ADFG   +         +  V T  Y +PEIL     G  +Y 
Sbjct: 451 DLKPQNLLINHTGAIKIADFGMA-RTFALPVRAYTHEVVTLWYRAPEILM----GASKYS 615

Query: 261 PECDWWSLGVCMYEMLYGETPFYAESLVETYGKIM 295
              D WS+G    +ML     F  +S ++   KI 
Sbjct: 616 TPVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIF 720
>17975
          Length = 449

 Score = 66.6 bits (161), Expect = 8e-11,   Method: Composition-based stats.
 Identities = 47/142 (33%), Positives = 81/142 (57%), Gaps = 9/142 (6%)
 Frame = +3

Query: 92  AVVKLKNADKVF-----AMKILNKWEMLKRAETACFREERDV-LVNGDSKWITTLHYAFQ 145
           AVVKL  A  VF     A+K+++K ++ + + +  F+E R + LV   +  +  L+    
Sbjct: 9   AVVKL--ARHVFTGEKVAVKVIDKTKLDEVSRSHLFQEVRCMKLVQHPN--VVRLYEVID 176

Query: 146 DDNNLYLVMDYYVGGDLLTLLSKFEDRLPEEMARFYLAEMVIAIDSVHQLHYVHRDIKPD 205
               LYL+++   GGD+   + +    L E++A+ Y  ++V AI   H+LH VHRD+KP+
Sbjct: 177 TQTKLYLILELGDGGDMYDYIMRHSGGLEEKLAKRYFRQIVEAISYCHKLHVVHRDLKPE 356

Query: 206 NIL-MDMNGHIRLADFG--SCL 224
           N++  +  G ++L DFG  +CL
Sbjct: 357 NVVFFEKPGLVKLTDFGFSTCL 422
>06405
          Length = 1965

 Score = 66.2 bits (160), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 56/225 (24%), Positives = 102/225 (45%), Gaps = 5/225 (2%)
 Frame = +1

Query: 72  LHREDFEILKVIGRGAFGEVAVVKLKNADKVFAMKILNKWEMLKRAETACFREERDVLVN 131
           + R +  +   +G G +G+V     K  +K+ A+K L +  M        F EE  ++  
Sbjct: 250 IERTEIAMKHRLGGGQYGDVYEAMWKRYNKIVAVKTLKEDTMALND----FLEEAAIMKE 417

Query: 132 GDSKWITTLHYAFQDDNNLYLVMDYYVGGDLLTLL--SKFEDRLPEEMARFYLAEMVIA- 188
                +  L      +   Y+V ++   G+LL  L  S  E+  P   A  Y+A  + + 
Sbjct: 418 MKHPNLVQLLGVCTREPPFYIVTEFMPHGNLLDYLRSSTREENGP--TALMYMATQIASG 591

Query: 189 IDSVHQLHYVHRDIKPDNILMDMNGHIRLADFGSCLKLMEDGTVQSSVAVGTP-DYISPE 247
           +  +   +++HRD+   N L+  +  +++ADFG   +LM+D T  + +    P  + +PE
Sbjct: 592 MAYLETKNFIHRDLAARNCLVADSNMVKVADFG-LARLMKDDTYTAHIGAKFPIKWTAPE 768

Query: 248 ILQAMEDGKGRYGPECDWWSLGVCMYEM-LYGETPFYAESLVETY 291
            L        R+    D W+ GV ++E+  YG +P+    L E Y
Sbjct: 769 GL-----AFNRFSTRSDIWAFGVLLWELATYGMSPYPGVELTEVY 888
>19094
          Length = 898

 Score = 65.1 bits (157), Expect = 3e-10,   Method: Composition-based stats.
 Identities = 34/89 (38%), Positives = 51/89 (57%), Gaps = 2/89 (2%)
 Frame = +1

Query: 192 VHQLHYVHRDIKPDNILMDMNGHIRLADFGSCLKLMEDGTVQSSVAVGTPDYISPEILQA 251
           +H    +HRDIK  NIL++  GH +LADFG   +L  D   + +  +GTP +++PE++Q 
Sbjct: 106 LHSRRKIHRDIKAGNILLNNEGHAKLADFGVAGQLT-DTMAKRNTVIGTPYWMAPEVIQE 282

Query: 252 MEDGKGRYGPEC--DWWSLGVCMYEMLYG 278
           +       G +C  D WSLG+   EM  G
Sbjct: 283 I-------GYDCVADIWSLGITALEMAEG 348
>26156
          Length = 479

 Score = 63.9 bits (154), Expect = 5e-10,   Method: Compositional matrix adjust.
 Identities = 36/108 (33%), Positives = 64/108 (59%), Gaps = 1/108 (0%)
 Frame = -1

Query: 76  DFEILKVIGRGAFGEVAVVKLKNADKVFAMKILNKWEMLKRAETACFREERDVLVNG-DS 134
           DF +L+VIGRG++ +V  V+ K   +++AMK++ K  +    +    + E+ V     + 
Sbjct: 386 DFLLLRVIGRGSYAKVLQVEHKRTKRIYAMKVIKKELVNDDEDIDWVQTEKHVFETATNY 207

Query: 135 KWITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSKFEDRLPEEMARFYL 182
            ++  LH  FQ ++ L+ V+++  GGDL+  + + + RLPEE ARF L
Sbjct: 206 PFLVGLHSCFQSESRLFFVIEFVNGGDLMFHMQR-QRRLPEEHARFTL 66
>26711
          Length = 405

 Score = 63.5 bits (153), Expect = 8e-10,   Method: Composition-based stats.
 Identities = 42/132 (31%), Positives = 63/132 (47%), Gaps = 2/132 (1%)
 Frame = -2

Query: 189 IDSVHQLHYVHRDIKPDNILM--DMNGHIRLADFGSCLKLMEDGTVQSSVAVGTPDYISP 246
           +  VH    VH D+KP N+L+  D    ++L DFG   KL      ++ +  GTP + SP
Sbjct: 377 LQHVHAQGVVHMDLKPSNLLLSGDKLDSVQLIDFGLARKLYPPQ--ETFLNHGTPGFTSP 204

Query: 247 EILQAMEDGKGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKERFQFPAQ 306
           E L              D W +GV  Y +L G++PF A+S  E+  K       F     
Sbjct: 203 EALDVKP-----ISTASDVWGVGVLAYILLSGQSPFQADSATESLKKTQTCDWSFDVCPS 39

Query: 307 VTDVSENAKDLI 318
            +++S++AKD I
Sbjct: 38  FSNMSQDAKDFI 3
>17722
          Length = 680

 Score = 63.5 bits (153), Expect = 8e-10,   Method: Compositional matrix adjust.
 Identities = 38/111 (34%), Positives = 56/111 (50%), Gaps = 5/111 (4%)
 Frame = -3

Query: 263 CDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKERFQFPAQVTDVSENAKDLIRRLI 322
            DWW  GV MYEM+ G  PFY       +  I+    +F       ++SE AK L+  L+
Sbjct: 678 VDWWGTGVVMYEMMCGRLPFYNRDHDVLFELILLQNVKFP-----RNLSEEAKTLLSGLL 514

Query: 323 CSR-EHRLG--QNGIEDFKKHPFFSGIDWDNI--RNCEAPYIPEVSSPTDT 368
               + RLG  +  + + K HPFF  I+WD++  +    P+ P+V S  DT
Sbjct: 513 AKNPKRRLGGSEADVTEIKTHPFFQCINWDDLAAKKITPPWKPDVKSSWDT 361
>16708
          Length = 1397

 Score = 62.4 bits (150), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 41/156 (26%), Positives = 78/156 (50%), Gaps = 13/156 (8%)
 Frame = -1

Query: 79   ILKVIGRGAFGEVAVVKLKNADKVFAMKI-------LNKWEMLKRAETACFREERDVLVN 131
            IL+V+G+G FG+V   +L +  +  A+K        L++ E L R E   +      L  
Sbjct: 1391 ILQVLGKGVFGKVYEARLLSTHEKAALKTSILCHHSLDEVEALGRIEGGFY------LAQ 1230

Query: 132  GDSKWITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSKFEDR-LP-----EEMARFYLAEM 185
                W+T L +       + +++ +Y  G L  + + ++++ +P       M      + 
Sbjct: 1229 MFGAWVTCLPFP-----KMNILLHFYEMGPLCNVYAHYKNKEMPIRWSNPAMVCCIAGQX 1065

Query: 186  VIAIDSVHQLHYVHRDIKPDNILMDMNGHIRLADFG 221
            V A++ +H+L  VH D+K DN+L+D +G+ +L D+G
Sbjct: 1064 VCALEHIHELGVVHMDVKADNVLVDAHGNCKLTDYG 957
>01718
          Length = 959

 Score = 61.2 bits (147), Expect = 4e-09,   Method: Compositional matrix adjust.
 Identities = 56/212 (26%), Positives = 98/212 (46%), Gaps = 8/212 (3%)
 Frame = +3

Query: 72  LHREDFEILKVIGRGAFGEVAVVKLKNADKVFAMKI----LNKWEMLKRAETACFREERD 127
           L R D  I + IG G F EV  V  +   +V A+K+     N+  ML+  +     +  +
Sbjct: 138 LTRLDDFICEKIGAGFFSEVFKVTHRITGQVMALKMNTMTSNRHNMLREVQLLNRLQHAN 317

Query: 128 VLVNGDSKWITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSKFEDRLPEEMARFYLAEMVI 187
           +L     +++    +  Q    L+ + +Y   G+L  LL K ++ LP          +  
Sbjct: 318 IL-----RFMGVCVHEGQ----LHALTEYIPSGNLEQLLEKKDEELPWTQRIQLTLGLAR 470

Query: 188 AIDSVHQLHYVHRDIKPDNILM---DMNG-HIRLADFGSCLKLMEDGTVQSSVAVGTPDY 243
            +D +H   ++HRD+   NIL+   D +G H  +ADFG   K+ +    +    VG+P +
Sbjct: 471 GLDYLHSTRFIHRDLTSKNILIRREDNHGYHAVIADFGLATKIPDPLDKEKLPTVGSPYW 650

Query: 244 ISPEILQAMEDGKGRYGPECDWWSLGVCMYEM 275
           ++PE+L         Y    D +S+G+ M E+
Sbjct: 651 MAPEVLNG-----HFYNERADLFSVGIIMCEI 731
>04591
          Length = 1117

 Score = 60.1 bits (144), Expect = 8e-09,   Method: Compositional matrix adjust.
 Identities = 39/126 (30%), Positives = 63/126 (50%)
 Frame = -2

Query: 150 LYLVMDYYVGGDLLTLLSKFEDRLPEEMARFYLAEMVIAIDSVHQLHYVHRDIKPDNILM 209
            YL+ +Y    DL  LL+    +      +  +++++  +  +H    +HRDIK  NIL+
Sbjct: 972 FYLIFEY-CDYDLAGLLNNLRVKFSLADKKNLMSQLLNGLFYIHTKQILHRDIKAANILL 796

Query: 210 DMNGHIRLADFGSCLKLMEDGTVQSSVAVGTPDYISPEILQAMEDGKGRYGPECDWWSLG 269
             +G ++LADFG     ++   + + V   T  Y  PE+L     G+  YGPE D W +G
Sbjct: 795 TRDGVLKLADFGLSRPWVKSKRLTNRVV--TLWYRPPELLL----GEREYGPEIDMWGVG 634

Query: 270 VCMYEM 275
             M EM
Sbjct: 633 CIMAEM 616
>19761
          Length = 473

 Score = 59.3 bits (142), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 39/109 (35%), Positives = 53/109 (48%), Gaps = 2/109 (1%)
 Frame = -3

Query: 169 FEDRLPEEMARFYLAEMVIAIDSVHQLHYV--HRDIKPDNILMDMNGHIRLADFGSCLKL 226
           F   LPE +   +L +   A++ +H    V  HRD+KP NI +   G +RL D G   KL
Sbjct: 444 FTAGLPERLIVCWLMQTASALNYMHTHTPVILHRDLKPQNIYVTEKGDVRLGDLGLARKL 265

Query: 227 MEDGTVQSSVAVGTPDYISPEILQAMEDGKGRYGPECDWWSLGVCMYEM 275
                  +S  VGT  Y+SPEIL         Y  + D WSLG   Y++
Sbjct: 264 TGPADFATS-QVGTIMYLSPEILSQQP-----YNSKSDIWSLGCVFYDI 136
>25445
          Length = 460

 Score = 58.5 bits (140), Expect = 2e-08,   Method: Composition-based stats.
 Identities = 25/75 (33%), Positives = 37/75 (49%), Gaps = 2/75 (2%)
 Frame = -1

Query: 1002 GCPASTGFPPKRKT--HQFFVKSFTAPTKCHQCTSLMVGLIRQGCSCEVCGFSCHITCVN 1059
             CP +   P    T  H+F   ++ +PT C  C SL+ GLI QG  C+ C  +CH  C  
Sbjct: 445  ACPGADNGPDSDATNLHKFKAHTYGSPTFCDHCGSLLYGLIHQGLKCDSCDMNCHKRCEK 266

Query: 1060 KAPTVCPVPPEQTKG 1074
              P +C +   + +G
Sbjct: 265  HVPRLCGMDHTERRG 221
>21079
          Length = 878

 Score = 57.0 bits (136), Expect = 6e-08,   Method: Compositional matrix adjust.
 Identities = 39/141 (27%), Positives = 70/141 (49%), Gaps = 2/141 (1%)
 Frame = +1

Query: 143 AFQDDNNLYLVMDYYVGGDLLTLLSKFEDRLPEEMARFYLAEMVIAIDSVHQLHYVHRDI 202
           AF+    + LVM++   G+L   + + +  L E     ++ ++   +  +H    +H D+
Sbjct: 28  AFEAPRTMVLVMEFVGAGELFERVIRDDFVLTERDCVHFVRQICSGVGYMHTQSILHLDL 207

Query: 203 KPDNILM--DMNGHIRLADFGSCLKLMEDGTVQSSVAVGTPDYISPEILQAMEDGKGRYG 260
           KP+N+L   D +  I++ DFG         ++Q  V  GTP++I+PE++   E       
Sbjct: 208 KPENVLCVSDNSNQIKIIDFGLARFYKPGDSLQ--VLFGTPEFIAPEVVNYDE-----IN 366

Query: 261 PECDWWSLGVCMYEMLYGETP 281
              D WS+GV  Y +L G +P
Sbjct: 367 FTTDMWSIGVICYILLSGLSP 429
>01966
          Length = 1735

 Score = 57.0 bits (136), Expect = 7e-08,   Method: Compositional matrix adjust.
 Identities = 30/87 (34%), Positives = 49/87 (56%), Gaps = 2/87 (2%)
 Frame = -1

Query: 137  ITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSKFEDR--LPEEMARFYLAEMVIAIDSVHQ 194
            I  L     +D  L+LV ++ +  DL   + KF +   L   + + Y+ ++V  I+  HQ
Sbjct: 1528 IVCLEDVIMEDERLFLVFEF-LSMDLKMYIDKFPEGVVLDRRLVKSYVFQIVTGINFCHQ 1352

Query: 195  LHYVHRDIKPDNILMDMNGHIRLADFG 221
               VHRD+KP N+L++  G I++ADFG
Sbjct: 1351 RRIVHRDLKPQNLLINHTGAIKIADFG 1271
>03508
          Length = 1463

 Score = 55.8 bits (133), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 34/104 (32%), Positives = 55/104 (52%), Gaps = 1/104 (0%)
 Frame = +1

Query: 179 RFYLAEMVIAIDSVHQLHYVHRDIKPDNILMDM-NGHIRLADFGSCLKLMEDGTVQSSVA 237
           RFYL E++ A+D  H +  +HRD+KP N+++D  N  +RL D+G  L       ++ +V 
Sbjct: 880 RFYLYELMKALDFCHSMGIMHRDVKPHNVMIDHENKKLRLIDWG--LAEFYHPGMEYNVR 1053

Query: 238 VGTPDYISPEILQAMEDGKGRYGPECDWWSLGVCMYEMLYGETP 281
           V +  +  PE+L   +     Y    D WSLG     M++ + P
Sbjct: 1054VASRYFKGPELLLDYQ----MYDYSLDMWSLGCMFASMIFRKEP 1173
>25019
          Length = 730

 Score = 55.8 bits (133), Expect = 1e-07,   Method: Composition-based stats.
 Identities = 27/65 (41%), Positives = 39/65 (60%)
 Frame = +3

Query: 205 DNILMDMNGHIRLADFGSCLKLMEDGTVQSSVAVGTPDYISPEILQAMEDGKGRYGPECD 264
           +N+L+D +GH++L DFG C + +  GT  +    GT +Y++PEIL     GK       D
Sbjct: 261 ENVLLDKDGHVKLTDFGLCKEAIT-GTRVTHTFCGTIEYMAPEILTRTGHGKA-----VD 422

Query: 265 WWSLG 269
           WWSLG
Sbjct: 423 WWSLG 437
>35187
          Length = 593

 Score = 55.8 bits (133), Expect = 2e-07,   Method: Composition-based stats.
 Identities = 25/63 (39%), Positives = 32/63 (50%), Gaps = 1/63 (1%)
 Frame = -3

Query: 1004 PASTGFPPKRKTHQFFVK-SFTAPTKCHQCTSLMVGLIRQGCSCEVCGFSCHITCVNKAP 1062
            P+ +  PP      FF K +F  PT CH CT ++ GLI  G  CEVC F  H  C+    
Sbjct: 354  PSDSPVPPDHGHGHFFTKKTFHKPTYCHHCTDILWGLIGVGYVCEVCNFVVHDRCMKTVV 175

Query: 1063 TVC 1065
            + C
Sbjct: 174  SPC 166
>00715
          Length = 1788

 Score = 55.5 bits (132), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 43/166 (25%), Positives = 76/166 (45%), Gaps = 21/166 (12%)
 Frame = +1

Query: 138 TTLHYAFQDDNNLYLVMDYYVGGDLLTLLSKFEDRLPEEMARFYLAEMVIAIDSVHQLHY 197
           T+LH  F+D    +L M+Y    +L T+L+  +  +   M      +M   +  +H ++ 
Sbjct: 133 TSLH-RFED--GAWLAMEYVGPLNLQTILNDHQQDIDSSMRLSLALQMARGLHYLHSINI 303

Query: 198 VHRDIKPDNILMDMNGHIRLADFGSCLKLMEDGT------------------VQSSVA-- 237
           VH D+KP N L+  +  +R+ADFG C +L   G                   VQ +    
Sbjct: 304 VHLDLKPANCLLTRDLKLRIADFGCCHQLTPTGLDMGEREGGMAGNELELTPVQGAWKNE 483

Query: 238 -VGTPDYISPEILQAMEDGKGRYGPECDWWSLGVCMYEMLYGETPF 282
             GT  Y +PE+L+ ++          D +SLG+ +++M   + P+
Sbjct: 484 LAGTLAYRAPELLKGLQPSV-----RSDVYSLGITLWQMCTRQGPY 606
>21433
          Length = 590

 Score = 55.1 bits (131), Expect = 3e-07,   Method: Composition-based stats.
 Identities = 36/102 (35%), Positives = 56/102 (54%)
 Frame = +2

Query: 181 YLAEMVIAIDSVHQLHYVHRDIKPDNILMDMNGHIRLADFGSCLKLMEDGTVQSSVAVGT 240
           Y+ ++  A++  H    +HRDIKP+N+L+ + G +++ADFG  +      + + +   GT
Sbjct: 182 YIYQLSSALEYCHYRKVIHRDIKPENLLLGLKGDLKIADFGWSV---HAPSSRRTTMCGT 352

Query: 241 PDYISPEILQAMEDGKGRYGPECDWWSLGVCMYEMLYGETPF 282
            DY+ PE    M +GK  +    D WSLGV  YE L G  P 
Sbjct: 353 LDYLPPE----MVEGK-THDENVDLWSLGVLCYEFLVGTPPL 463
>14116
          Length = 1017

 Score = 54.7 bits (130), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 53/215 (24%), Positives = 101/215 (46%), Gaps = 6/215 (2%)
 Frame = -1

Query: 68  KQMRLHREDFEILKVIGRGAFGEV----AVVKLKNADKVFAMKILNKWEMLKRAETACFR 123
           + + + RE   + + IG+G FG V      +  +  D + A+K L+     +  E   F 
Sbjct: 657 ESLLIDREFLTMGEEIGKGNFGCVKRGFLTLPEQKGDILVAVKTLHN-NNPREIELQSFL 481

Query: 124 EERDVLVN-GDSKWITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSKFEDRLPEEMARFYL 182
           +E  ++ +   S  +T +      D+   +V+ +   GDLLT +   + +   +    Y 
Sbjct: 480 QEALIMKDFHHSNVLTLIGICLNLDDMPLVVLPFMKHGDLLTYIRDDQHQPTIKDLIMYG 301

Query: 183 AEMVIAIDSVHQLHYVHRDIKPDNILMDMNGHIRLADFGSCLKLMEDGTVQS-SVAVGTP 241
            ++   +D +  L +VHRD+   N ++D + H+++ADFG    + E     S +     P
Sbjct: 300 VDIARGMDYLAGLKFVHRDLAARNCMLDEDFHVKVADFGLARDIYEKEYYSSENKKAKLP 121

Query: 242 DYISPEILQAMEDGKGRYGPECDWWSLGVCMYEML 276
             +    L+++E  KG Y  + D WS GV ++E+L
Sbjct: 120 --VKWMALESLE--KGNYDSKTDVWSYGVVLWELL 28
>00392
          Length = 668

 Score = 54.7 bits (130), Expect = 4e-07,   Method: Compositional matrix adjust.
 Identities = 54/224 (24%), Positives = 102/224 (45%), Gaps = 9/224 (4%)
 Frame = +3

Query: 110 KWEMLKRAETACFREERDVLVNGDSKWITTLHYAFQDDNN-----LYLVMDYYVGGDLLT 164
           KW    +AE   F+EE ++L       I      +++ N+     + LV +    G L T
Sbjct: 45  KW---NKAERQRFKEEAEMLKELQHPNIVRFFDYWEEHNHRNRKVIILVTELMTSGTLKT 215

Query: 165 LLSKFEDRLPEEMARFYLAEMVIAIDSVHQLH--YVHRDIKPDNILMDM-NGHIRLADFG 221
            L +F+ +   ++ + +  +++  +  +H      +HRD+K DNI +    G +++ D G
Sbjct: 216 YLKRFK-KPNVKILKNWCRQVLKGLYFLHTRTPPVIHRDLKCDNIFITGPTGSVKIGDLG 392

Query: 222 SCLKLMEDGTVQSSVAVGTPDYISPEILQAMEDGKGRYGPECDWWSLGVCMYEMLYGETP 281
             L  +++ +   SV +GTP++++PE+ +        Y    D ++ G+CM EM   E P
Sbjct: 393 --LATLKNQSFAKSV-IGTPEFMAPEMYEE------HYDEAVDVYAFGMCMLEMASSEYP 545

Query: 282 FYAESLVETYGKIMNHKERFQFPAQVTDVS-ENAKDLIRRLICS 324
           +   S      +I         P  +  V+    +D+I   ICS
Sbjct: 546 Y---SECSNAAQIYKRVTSGVLPEALDKVAITEIRDIIHHCICS 668
>33586
          Length = 551

 Score = 53.5 bits (127), Expect = 7e-07,   Method: Composition-based stats.
 Identities = 26/50 (52%), Positives = 34/50 (68%)
 Frame = +2

Query: 136 WITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSKFEDRLPEEMARFYLAEM 185
           +I  LHYAFQ +  LYL++++  GGDL T LSK E    EE  +FYLAE+
Sbjct: 404 FIVHLHYAFQTEGKLYLILEFLRGGDLFTRLSK-EVMFTEEDVKFYLAEL 550
>11185
          Length = 473

 Score = 53.5 bits (127), Expect = 8e-07,   Method: Compositional matrix adjust.
 Identities = 32/115 (27%), Positives = 51/115 (44%), Gaps = 21/115 (18%)
 Frame = +1

Query: 185 MVIAIDSVHQLHYVHRDIKPDNILMDMNGHIRLADFGSC-----------LKLMEDG--- 230
           +V  +  +H L  +  D++P  +L+D +G ++ ADFG              K  E G   
Sbjct: 28  LVTGLHYIHSLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEAGDQW 207

Query: 231 TVQSSVAV-------GTPDYISPEILQAMEDGKGRYGPECDWWSLGVCMYEMLYG 278
            +QS+  +       G+P Y++PE+ Q  E          D W+LG   YEM  G
Sbjct: 208 NIQSAEEMMKQVPTSGSPTYMAPEVFQGAEPSI-----MSDLWALGCVFYEMFSG 357
>29581
          Length = 1278

 Score = 52.0 bits (123), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 40/137 (29%), Positives = 65/137 (47%), Gaps = 2/137 (1%)
 Frame = -2

Query: 148  NNLYLVMDYYVGGDLLTLLSKFEDRLPEEMARFYLAEMVIAIDSVHQLHYVHRDIKPDNI 207
            ++L+LVM+Y    DL +LL        E   +  + +++  +  +H+   +HRD+K  N+
Sbjct: 1130 DSLFLVMEY-CEQDLASLLDNMPAPFSESQVKCIVLQLLKGLRYLHEAFIIHRDLKVSNL 954

Query: 208  LMDMNGHIRLADFGSCLKLMEDGTVQSSVA--VGTPDYISPEILQAMEDGKGRYGPECDW 265
            LM   G +++ADFG        G  Q  +   V T  Y +PE+L     G   +    D 
Sbjct: 953  LMTDKGCVKIADFGLARNY---GKPQKPMTPKVVTLWYRAPELL----FGSKTHSTAIDM 795

Query: 266  WSLGVCMYEMLYGETPF 282
            WS G  + E+L G  P 
Sbjct: 794  WSAGCILGELL-GHKPL 747
>27546
          Length = 426

 Score = 51.2 bits (121), Expect = 4e-06,   Method: Composition-based stats.
 Identities = 28/100 (28%), Positives = 50/100 (50%)
 Frame = -1

Query: 122 FREERDVLVNGDSKWITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSKFEDRLPEEMARFY 181
           F  E ++L   D   I  +H   Q    +++ M Y   GD+L+ + K    + E   + +
Sbjct: 339 FPRELEILTRLDHPNIIQIHSILQRGPKIFIFMRYAEKGDMLSHIKK-TGPIDEAQTKVW 163

Query: 182 LAEMVIAIDSVHQLHYVHRDIKPDNILMDMNGHIRLADFG 221
             +M  A+  +H     HRD+K +NIL+    ++++ADFG
Sbjct: 162 FFQMAKALQYLHSHDIAHRDLKCENILLSKRLNVKIADFG 43
>01756
          Length = 1858

 Score = 51.2 bits (121), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 62/215 (28%), Positives = 92/215 (42%), Gaps = 16/215 (7%)
 Frame = -3

Query: 77   FEILKVIGRGAFGEVAVVKLKNADKVFAMKILNKWEMLKRAETACFREERDV----LVNG 132
            +E L  IG+G FGEV   + K   +V AMK   K  M    E       R++    L+N 
Sbjct: 1736 YEKLAKIGQGTFGEVFKARCKKTKQVVAMK---KVLMDNEKEGFPITALREIKILQLLNH 1566

Query: 133  DSK------WITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSKFED--RLPEEMARFYLAE 184
            ++         T    A +  +  YLV ++    DL  LLS       LPE   +  + +
Sbjct: 1565 ENVVDLIEICSTKATSANRYKSMFYLVFEF-CEHDLAGLLSNMSVVFNLPE--IKEVMKQ 1395

Query: 185  MVIAIDSVHQLHYVHRDIKPDNILMDMNGHIRLADFGSC----LKLMEDGTVQSSVAVGT 240
            ++  +  +H+   +HRD+K  NIL+   G ++LADFG      + L +     + V   T
Sbjct: 1394 LMNGLYYIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRVV--T 1221

Query: 241  PDYISPEILQAMEDGKGRYGPECDWWSLGVCMYEM 275
              Y  PE+L     G   Y    D W  G  M EM
Sbjct: 1220 LWYRPPELLL----GDRNYSTAIDQWGAGCIMAEM 1128
>17591
          Length = 474

 Score = 37.4 bits (85), Expect(2) = 1e-05,   Method: Compositional matrix adjust.
 Identities = 19/51 (37%), Positives = 30/51 (58%), Gaps = 3/51 (5%)
 Frame = +3

Query: 325 REHRLG-QNGIEDFKKHPFFSGIDWDNIRN--CEAPYIPEVSSPTDTSNFD 372
           +E RLG +   E+ ++  FF+ I+WD++ N   + PY P VS   D  +FD
Sbjct: 147 KEERLGAKRDFEEIQEKAFFADINWDDLYNKKVQPPYNPNVSGQLDLRHFD 299

 Score = 32.0 bits (71), Expect(2) = 1e-05,   Method: Composition-based stats.
 Identities = 18/61 (29%), Positives = 32/61 (52%)
 Frame = +2

Query: 273 YEMLYGETPFYAESLVETYGKIMNHKERFQFPAQVTDVSENAKDLIRRLICSREHRLGQN 332
           +EMLYG  PFY+    E Y  I+    R +     T+VS   ++++  L+  ++ + G+ 
Sbjct: 2   FEMLYGLPPFYSRDTSEMYENILYKPLRLR-----TNVSAAGRNILEELL--KKEKGGET 160

Query: 333 G 333
           G
Sbjct: 161 G 163
>19361
          Length = 685

 Score = 47.8 bits (112), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 23/66 (34%), Positives = 30/66 (45%)
 Frame = -1

Query: 1014 KTHQFFVKSFTAPTKCHQCTSLMVGLIRQGCSCEVCGFSCHITCVNKAPTVCPVPPEQTK 1073
            K H F V++F     C  C + M GLI QG  C+ CG   H  C  + P  C    +  K
Sbjct: 322  KPHVFKVQNFNGLNWCELCANFMWGLIAQGVKCQDCGVQTHKKCSERMPNECMPNMKYVK 143

Query: 1074 GPLGID 1079
               G+D
Sbjct: 142  RLYGVD 125
>12672
          Length = 773

 Score = 47.4 bits (111), Expect = 6e-05,   Method: Compositional matrix adjust.
 Identities = 29/85 (34%), Positives = 45/85 (52%), Gaps = 3/85 (3%)
 Frame = +3

Query: 197 YVHRDIKPDNILMDMNGHIRLADFGSCLKL--MEDGTVQ-SSVAVGTPDYISPEILQAME 253
           +VHRDIK  NIL+D     ++ DF + +     E  TVQ +SV +GT  Y++PE +    
Sbjct: 54  HVHRDIKTANILLDSEYTAKVGDFATVVSAPSGEGKTVQNASVVIGTAAYLAPEAIHF-- 227

Query: 254 DGKGRYGPECDWWSLGVCMYEMLYG 278
                   + D +S GV + E++ G
Sbjct: 228 ----DVSTKLDSYSFGVVLLEVITG 290
>20152
          Length = 445

 Score = 46.6 bits (109), Expect = 8e-05,   Method: Compositional matrix adjust.
 Identities = 31/102 (30%), Positives = 48/102 (47%)
 Frame = +1

Query: 246 PEILQAMEDGKGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKERFQFPA 305
           PEIL     G     P  D WSLGV +Y ++ GE PF   +  ET   IM+   R+Q P 
Sbjct: 1   PEILL----GDSYDAPAVDVWSLGVILYMLVVGEAPFQEANDSETLTMIMDC--RYQIPP 162

Query: 306 QVTDVSENAKDLIRRLICSREHRLGQNGIEDFKKHPFFSGID 347
               +S   +DLI +++  +   + +  +     HP+ +  D
Sbjct: 163 H---ISHKCQDLIEKML--QREPVDRASLPHILAHPWLNDGD 273
>21808
          Length = 1011

 Score = 46.6 bits (109), Expect = 8e-05,   Method: Compositional matrix adjust.
 Identities = 39/170 (22%), Positives = 72/170 (42%), Gaps = 2/170 (1%)
 Frame = +1

Query: 137 ITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSKFEDRLPEEMARFYLAEMVIAIDSVHQLH 196
           +  L+     D+ ++++ +    G LL  L      L         A++   +  +   +
Sbjct: 118 LIQLYAVCTQDDPIFIITELMKNGSLLEFLQGKGRVLKLPALIDIGAQIACGMAYLESQN 297

Query: 197 YVHRDIKPDNILMDMNGHIRLADFGSCLKLMEDGTVQSSVAVGTP-DYISPEILQAMEDG 255
           Y+HRD+   NIL+  N  +++ADFG    + ED   ++ V    P  + +PE        
Sbjct: 298 YIHRDLAARNILVSDNNTVKIADFGLARVIKED-EYEARVGARFPIKWTAPE-----AAN 459

Query: 256 KGRYGPECDWWSLGVCMYEML-YGETPFYAESLVETYGKIMNHKERFQFP 304
             R+  + D WS G+ + E + YG  P+   +  E   ++  H  R   P
Sbjct: 460 YNRFTIKSDVWSFGILLTETVTYGRVPYPGMTNAEVLHQV-EHGYRMPCP 606
>07836
          Length = 1478

 Score = 45.4 bits (106), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 43/142 (30%), Positives = 67/142 (47%), Gaps = 16/142 (11%)
 Frame = -1

Query: 150  LYLVMDYYVGGDLL-TLLSKFEDRLPEEMARFYLAEMVIAIDSVHQLHY----------- 197
            L+L+ DY+  G L   LLS+  D    EM    LA    AI  +  LH            
Sbjct: 1328 LFLITDYHENGSLHDYLLSRVLDS--SEM----LALAHSAICGLAHLHIEIFGTRGKPAI 1167

Query: 198  VHRDIKPDNILMDMNGHIRLADFGSCLKLMEDGT---VQSSVAVGTPDYISPEILQAMED 254
             HRDIK  NIL+  NG   +AD G  ++ + +     V  +   GT  Y++PE+L+ + +
Sbjct: 1166 AHRDIKSKNILVKKNGTCCIADLGLAVRYISESNEVDVAPNPRQGTKRYMAPEVLEMLLN 987

Query: 255  GKGRYG-PECDWWSLGVCMYEM 275
             K      + D ++ G+ M+E+
Sbjct: 986  VKNFDAFKQADMYAFGLVMWEI 921
>22804
          Length = 967

 Score = 45.4 bits (106), Expect = 2e-04,   Method: Composition-based stats.
 Identities = 18/52 (34%), Positives = 26/52 (50%)
 Frame = -3

Query: 1014 KTHQFFVKSFTAPTKCHQCTSLMVGLIRQGCSCEVCGFSCHITCVNKAPTVC 1065
            + H+F   ++T PT C  C  L+ G  + G  C  CG++CH  C    P  C
Sbjct: 836  QPHRFEKYTYTTPTYCDFCQQLLWGFSKTGTHCVDCGYNCHDKCQPLVPKTC 681
>11353
          Length = 454

 Score = 45.4 bits (106), Expect = 2e-04,   Method: Composition-based stats.
 Identities = 18/52 (34%), Positives = 26/52 (50%)
 Frame = +1

Query: 1014 KTHQFFVKSFTAPTKCHQCTSLMVGLIRQGCSCEVCGFSCHITCVNKAPTVC 1065
            + H+F   ++T PT C  C  L+ G  + G  C  CG++CH  C    P  C
Sbjct: 136  QPHRFEKYTYTTPTYCDFCQQLLWGFSKTGTHCVDCGYNCHDKCQPLVPKTC 291
>28638
          Length = 1458

 Score = 45.1 bits (105), Expect = 3e-04,   Method: Composition-based stats.
 Identities = 31/93 (33%), Positives = 46/93 (49%), Gaps = 4/93 (4%)
 Frame = -1

Query: 194 QLHYVHRDIKPDNILM--DMNGHIRLADFGSCLKLMED--GTVQSSVAVGTPDYISPEIL 249
           +++ +H D+KP+NIL+       I++ DFGS  +L +     +QS        Y SPE+L
Sbjct: 777 EMNIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRF------YRSPEVL 616

Query: 250 QAMEDGKGRYGPECDWWSLGVCMYEMLYGETPF 282
             +      Y    D WSLG  + EM  GE P 
Sbjct: 615 LGVP-----YDLAIDMWSLGCILVEMHTGEPPL 532
>17300
          Length = 480

 Score = 44.7 bits (104), Expect = 3e-04,   Method: Composition-based stats.
 Identities = 29/91 (31%), Positives = 45/91 (49%), Gaps = 4/91 (4%)
 Frame = +1

Query: 197 YVHRDIKPDNILMDMNGHIRLADFGSCLKLMEDGTVQSSVAVGTP---DYISPEILQAME 253
           YVHRD+   NIL++     ++ADFG   ++  D T  +    G      + +PE +    
Sbjct: 37  YVHRDLAARNILVNEILVCKVADFGLSREIESDTTEGAYTTKGGKIPVRWTAPEAI---- 204

Query: 254 DGKGRYGPECDWWSLGVCMYE-MLYGETPFY 283
               ++    D WS GV M+E M YGE P++
Sbjct: 205 -AYRKFTSASDVWSFGVVMWEVMSYGERPYW 294
>01431
          Length = 1309

 Score = 43.1 bits (100), Expect = 9e-04,   Method: Compositional matrix adjust.
 Identities = 53/261 (20%), Positives = 109/261 (41%), Gaps = 24/261 (9%)
 Frame = +2

Query: 1244 IALGNEEGLFVVHVT-KDEIVRVGDNKKIHQIELIPSDQLVAVISGRNRHVRLFPMSAL- 1301
            + +G E GL ++  + + ++ ++   ++  Q+E++    ++  ISG+   VR++ +S L 
Sbjct: 65   LLIGTENGLMLLDRSGQGKVYQLISRRRFQQMEVLEGQNILVTISGKKNRVRVYYLSWLK 244

Query: 1302 ------DG------RETDFYKLAETKGCQTIAAGKVRHGALSCLCVAMKRQVLCYEL--- 1346
                  DG      R   +  + + +G        V++  +  L +A+K  +  Y     
Sbjct: 245  SKILRTDGLSDQVERRNGWINVGDLQGAVHFKI--VKYERIKFLVIALKDSIEIYAWAPK 418

Query: 1347 -FQSKTRHRKFKEIQ-VPCNVQWMAIFSEHLCVGFQSGFLRYPLNGEGGPCNMLHSNDHT 1404
             +      + F E++  P  V         L V + S    + ++ +      ++   HT
Sbjct: 419  PYHKFMAFKNFGELEHRPLLVDLTIEDQSRLKVIYGSAEGFHAVDLDSAEVYDIYLPKHT 598

Query: 1405 L-SFISHQPMDALCAVEISNK---EYLLCFNSIGIYTDCQGRRSRQQELMWPANPSSCCY 1460
              + I H      C V + N    + LLC+++ G+Y +  GR S+   L W   P+S  Y
Sbjct: 599  QGAIIPH------CIVALPNSNGMQLLLCYDNEGVYVNTAGRVSKNIVLQWGEMPTSVAY 760

Query: 1461 -NAPYLSVYSENAVDIFDVNS 1480
                 +  +   A++I  V S
Sbjct: 761  IGTGQIMGWGNKAIEIRSVES 823
>04852
          Length = 1462

 Score = 42.4 bits (98), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 31/108 (28%), Positives = 51/108 (47%), Gaps = 1/108 (0%)
 Frame = +1

Query: 198 VHRDIKPDNILMDMNGHIRLADFGSCLKLMEDGTVQSSVAVGTPDYISPEILQAMEDGKG 257
           +HRD+   N+L+     +++ADFG  L    D   + S       +++PE L  M     
Sbjct: 391 IHRDLAARNVLVTEEHVLKIADFG--LSRTGDYYKKRSGGRLPVKWMAPEALFDM----- 549

Query: 258 RYGPECDWWSLGVCMYEML-YGETPFYAESLVETYGKIMNHKERFQFP 304
           RY  + D WS GV ++E+   G  P+ +    E Y K+++   R   P
Sbjct: 550 RYTTKSDVWSFGVVLWEIFSLGGMPYASIPNEELYSKLLDDAYRMPRP 693
>29590
          Length = 320

 Score = 42.0 bits (97), Expect = 0.002,   Method: Composition-based stats.
 Identities = 21/48 (43%), Positives = 27/48 (56%), Gaps = 3/48 (6%)
 Frame = +3

Query: 238 VGTPDYISPEILQAMEDGKGRYGP---ECDWWSLGVCMYEMLYGETPF 282
           +GTPDY++PE+L         Y P   + D WSLGV  Y ML   +PF
Sbjct: 57  IGTPDYVAPEVLD--------YEPLSIQTDMWSLGVLSYVMLTACSPF 176
>28157
          Length = 400

 Score = 41.2 bits (95), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 25/87 (28%), Positives = 46/87 (52%), Gaps = 6/87 (6%)
 Frame = +3

Query: 142 YAFQDDNNLYLVMDYYVGGDLLTLL--SKFEDRLPEEMARFYLAEMVIAIDSVHQLH--- 196
           Y    D+ + LVM+Y  GG L  +L  S  + +     A  +L +  + ++ +H +    
Sbjct: 108 YGACRDHPVCLVMEYAEGGSLYNVLHGSGPQPQYTAAHAMNWLLQCALGVEYLHGMKPKA 287

Query: 197 YVHRDIKPDNILMDMNG-HIRLADFGS 222
            +HRD+KP N+L+   G  +++ DFG+
Sbjct: 288 LIHRDLKPPNLLLIQCGTKLKICDFGT 368
>27274
          Length = 396

 Score = 41.2 bits (95), Expect = 0.004,   Method: Composition-based stats.
 Identities = 23/76 (30%), Positives = 38/76 (50%), Gaps = 11/76 (14%)
 Frame = -1

Query: 258 RYGPECDWWSLGVCMYEMLYGETPF--------YAESLVETYGKIMNHKERFQFPAQVTD 309
           ++GP  D WSLG+ ++E+L G  PF         A +++  Y +I+    R      V D
Sbjct: 357 QHGPTVDMWSLGILLHELLSGHVPFEPERGSRQMARNMMAVYAQIIRGSSR-----DVCD 193

Query: 310 ---VSENAKDLIRRLI 322
              +S +  D +RRL+
Sbjct: 192 GLALSTHGADFLRRLV 145
>07833
          Length = 1504

 Score = 41.2 bits (95), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 28/99 (28%), Positives = 41/99 (41%)
 Frame = -3

Query: 210  DMNGHIRLADFGSCLKLMEDGTVQSSVAVGTPDYISPEILQAMEDGKGRYGPECDWWSLG 269
            D+   I +AD+  C    E G V S      P +++PE LQ   D         D WS  
Sbjct: 1199 DLTARINMADY--CFSFHEKGKVYS------PAWMAPEALQRRPDDINTRA--ADMWSFA 1050

Query: 270  VCMYEMLYGETPFYAESLVETYGKIMNHKERFQFPAQVT 308
            + M+E+   E PF   S +E   K+     R   P  ++
Sbjct: 1049 ILMWELETREVPFAELSSMEVGMKVALEGLRISIPPGIS 933
>32957
          Length = 645

 Score = 40.8 bits (94), Expect = 0.005,   Method: Composition-based stats.
 Identities = 16/41 (39%), Positives = 26/41 (63%)
 Frame = +3

Query: 239 GTPDYISPEILQAMEDGKGRYGPECDWWSLGVCMYEMLYGE 279
           GT +Y++PE+ +  E     YG E DWW LG+ ++E+L  +
Sbjct: 51  GTREYMAPEVHERKE-----YGKEVDWWGLGILLHELLAAQ 158
>02638
          Length = 1490

 Score = 40.8 bits (94), Expect = 0.005,   Method: Composition-based stats.
 Identities = 27/107 (25%), Positives = 45/107 (42%)
 Frame = +1

Query: 238 VGTPDYISPEILQAMEDGKGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNH 297
           +GT  +++PE+L+        YG  CD WS+G  M EM     P+ +  +      I   
Sbjct: 19  LGTIAFMAPEVLRGES-----YGRACDVWSVGCVMIEMCTCRPPWNSHDISNHLALIFKI 183

Query: 298 KERFQFPAQVTDVSENAKDLIRRLICSREHRLGQNGIEDFKKHPFFS 344
                 P    ++S   +DL+ R  C  +    +   +D   HP F+
Sbjct: 184 ASSVDPPPIPENMSPPVRDLMLR--CLEQDSDFRPSAKDLLMHPLFT 318
>37063
          Length = 455

 Score = 40.8 bits (94), Expect = 0.005,   Method: Composition-based stats.
 Identities = 25/78 (32%), Positives = 41/78 (52%), Gaps = 7/78 (8%)
 Frame = -2

Query: 202 IKPDNIL---MDMNGHIRLADF--GSCLKLMEDGTVQSSV--AVGTPDYISPEILQAMED 254
           +KP+NIL   +D    +++ DF   S +    DGT    +   VG+ +Y++PE++ A   
Sbjct: 454 LKPENILCEHLDEVVPLKICDFDLASGINCDGDGTKTPELLTPVGSAEYMAPEVVDAWVG 275

Query: 255 GKGRYGPECDWWSLGVCM 272
               Y   CD WSLG+ +
Sbjct: 274 ESFSYDKRCDMWSLGIIL 221
>38560
          Length = 479

 Score = 40.0 bits (92), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 18/48 (37%), Positives = 27/48 (56%)
 Frame = -3

Query: 235 SVAVGTPDYISPEILQAMEDGKGRYGPECDWWSLGVCMYEMLYGETPF 282
           +   G+P Y +PE++  +E      G E D WS+GV +Y +L G  PF
Sbjct: 411 TTCCGSPAYAAPELISGLE----YLGSEADIWSMGVLLYALLCGYLPF 280
>09007
          Length = 1440

 Score = 40.0 bits (92), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 50/244 (20%), Positives = 107/244 (43%), Gaps = 21/244 (8%)
 Frame = -1

Query: 60  AKPFTSKVKQMR----LHREDFEILKVIGRGAFGEV--AVVKLKNADKV-FAMKILNKWE 112
           ++P ++ V+  R    + ++   + K +G+G FG V  A+   ++ +KV  A+K L+K +
Sbjct: 936 SRPVSAVVRPARGKQLISKDCVALSKSLGQGHFGTVRQAIWTAESGEKVQVAVKCLSKDK 757

Query: 113 MLKRAETACFREERDVLVNGDSKWITTLHYAFQDDN-NLYLVMDYYVGGDLLTLLSKFED 171
           + K  +   F +E  ++   D + I  ++    D+  ++ LV +      LL  + +   
Sbjct: 756 IHKDGQE--FLKETAIMQMLDHENIVRVYGVVMDNGADIMLVTELAPMRSLLECVKEVSA 583

Query: 172 RLPEEMARF--YLAEMVIAIDSVHQLHYVHRDIKPDNILMDMNGHIRLADFGSCLKLMED 229
           R+   + R   +  ++   +  +     VHRD+   NIL+     ++++D G        
Sbjct: 582 RVDFSVPRLCDFSQQVCDGMSYLESKRLVHRDLAARNILLFSKSKVKISDVG-------- 427

Query: 230 GTVQSSVAVGTPDYISPEILQAMEDGKGRYGPE----------CDWWSLGVCMYEML-YG 278
             V  ++  G   Y S + +  +++      PE           D W+ GV ++E   +G
Sbjct: 426 --VSGALGAGKEYYQSQQTIH-LQNAVAWCAPESFRNLCFSSASDVWAFGVLLWEFFTHG 256

Query: 279 ETPF 282
             P+
Sbjct: 255 FQPW 244
>04138
          Length = 800

 Score = 40.0 bits (92), Expect = 0.009,   Method: Compositional matrix adjust.
 Identities = 29/88 (32%), Positives = 40/88 (45%), Gaps = 4/88 (4%)
 Frame = +1

Query: 192 VHQLHYVHRDIKPDNILMDMNGHIRLADFGSC----LKLMEDGTVQSSVAVGTPDYISPE 247
           +H+   +HRD+K  NIL+   G ++LADFG      + L +     + V   T  Y  PE
Sbjct: 61  IHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRVV--TLWYRPPE 234

Query: 248 ILQAMEDGKGRYGPECDWWSLGVCMYEM 275
           +L     G   Y    D W  G  M EM
Sbjct: 235 LLL----GDRNYSTAIDQWGAGCIMAEM 306
>37602
          Length = 804

 Score = 38.5 bits (88), Expect = 0.022,   Method: Compositional matrix adjust.
 Identities = 23/71 (32%), Positives = 36/71 (50%)
 Frame = -1

Query: 150 LYLVMDYYVGGDLLTLLSKFEDRLPEEMARFYLAEMVIAIDSVHQLHYVHRDIKPDNILM 209
           L++ M+Y  GG  +  +      L E    F   E +  +  +H+   +HRDIK  NIL+
Sbjct: 294 LWIAMEY-CGGGSMQDIYHVTGPLTEPQIAFVCRETLKGLHYLHRRGKMHRDIKGANILL 118

Query: 210 DMNGHIRLADF 220
              G ++LADF
Sbjct: 117 TEEGDVKLADF 85
>07291
          Length = 833

 Score = 38.5 bits (88), Expect = 0.024,   Method: Compositional matrix adjust.
 Identities = 23/94 (24%), Positives = 46/94 (48%), Gaps = 3/94 (3%)
 Frame = +1

Query: 192 VHQLHYVHRDIKPDNILMDMNGHIRLADFGSCLKLMEDG--TVQSSVAVGTPDYISPEIL 249
           + ++  VHR++   N ++  +G ++L+D+G    L      T   S A     +++PE +
Sbjct: 97  LQEVKVVHRNLAARNCIVTEDGRLQLSDYGVTGSLFPQSYYTADDSPARDLVKWMAPETI 276

Query: 250 QAMEDGKGRYGPECDWWSLGVCMYEMLY-GETPF 282
                    +  + D W+ GV ++E+L  G TP+
Sbjct: 277 DNFH-----FSSKSDVWAFGVVLWELLTRGITPY 363
>18481
          Length = 437

 Score = 38.1 bits (87), Expect = 0.030,   Method: Composition-based stats.
 Identities = 26/87 (29%), Positives = 43/87 (49%), Gaps = 3/87 (3%)
 Frame = -1

Query: 138 TTLHYAFQDDNNLYLVMDYYVGGDLLTLLSKFEDRLPEEMARFYLAEMVIAIDSVHQLHY 197
           T  HY  +   N  LVM+  +G  L  L    + R   +       +++  ++ +HQ  +
Sbjct: 305 TMYHYGTEKHFNA-LVMEL-LGPSLEELFVICKRRFTLKTILMVSDQLLSRLEFIHQKCF 132

Query: 198 VHRDIKPDNILMDMNGH---IRLADFG 221
           +HRD+KPDN LM +  H   + + DFG
Sbjct: 131 IHRDLKPDNFLMGLGRHCHRLYIIDFG 51
>18996
          Length = 491

 Score = 38.1 bits (87), Expect = 0.031,   Method: Compositional matrix adjust.
 Identities = 26/86 (30%), Positives = 41/86 (47%), Gaps = 2/86 (2%)
 Frame = +2

Query: 198 VHRDIKPDNILMDMNGHIRLADFGSCLKLMEDGTVQSSVAVGTP-DYISPEILQAMEDGK 256
           +HRD+   NIL+D +  ++++DFG       DG          P  + SPE ++      
Sbjct: 2   IHRDLAARNILVDRSC-VKISDFGLAQFANADGYYYGISQRDIPIKWYSPEAIETC---- 166

Query: 257 GRYGPECDWWSLGVCMYEMLY-GETP 281
            ++    D WS GV ++EM   GE P
Sbjct: 167 -KFSSYSDVWSYGVTLFEMFSRGEIP 241
>19301
          Length = 712

 Score = 37.4 bits (85), Expect = 0.053,   Method: Compositional matrix adjust.
 Identities = 17/71 (23%), Positives = 40/71 (56%)
 Frame = +2

Query: 152 LVMDYYVGGDLLTLLSKFEDRLPEEMARFYLAEMVIAIDSVHQLHYVHRDIKPDNILMDM 211
           ++M+Y   G L  +L   ++ +P  +   +  ++   ++ +H    +HRD+K  N+L+  
Sbjct: 500 IIMEYCPYGQLYEVLRDGKE-IPPALVLDWSKQIASGMNYLHSHKIIHRDLKSPNVLVAK 676

Query: 212 NGHIRLADFGS 222
           N  ++++DFG+
Sbjct: 677 NDVVKISDFGT 709
>17516
          Length = 453

 Score = 37.0 bits (84), Expect = 0.068,   Method: Composition-based stats.
 Identities = 16/41 (39%), Positives = 27/41 (65%)
 Frame = -3

Query: 239 GTPDYISPEILQAMEDGKGRYGPECDWWSLGVCMYEMLYGE 279
           GTP Y++PE+L      KG+Y  + D +SL + ++E+ YG+
Sbjct: 433 GTPVYMAPEVLLQ----KGQYDMKADVYSLAIILWELWYGQ 323
>31489
          Length = 329

 Score = 37.0 bits (84), Expect = 0.071,   Method: Composition-based stats.
 Identities = 20/67 (29%), Positives = 41/67 (61%), Gaps = 1/67 (1%)
 Frame = +3

Query: 143 AFQDDNNLYLVMDYYVGGDLLTLLSKFEDR-LPEEMARFYLAEMVIAIDSVHQLHYVHRD 201
           ++ D  ++++V D  +  DL  ++  + D+ L EE  R++L +++  +  +H  + VHRD
Sbjct: 72  SYHDFKDIHVVFDL-MESDLHRII--YSDQPLTEEHIRYFLYQILRGLKYIHSANVVHRD 242

Query: 202 IKPDNIL 208
           +KP N+L
Sbjct: 243 LKPSNLL 263
>26009
          Length = 886

 Score = 37.0 bits (84), Expect = 0.072,   Method: Compositional matrix adjust.
 Identities = 14/32 (43%), Positives = 23/32 (71%)
 Frame = +3

Query: 178 ARFYLAEMVIAIDSVHQLHYVHRDIKPDNILM 209
           A+  + ++V A+D +H    VHRDIKP+N+L+
Sbjct: 717 AKSVMKQLVSALDFMHSKQLVHRDIKPENVLI 812
>20640
          Length = 1492

 Score = 35.8 bits (81), Expect = 0.14,   Method: Compositional matrix adjust.
 Identities = 29/110 (26%), Positives = 50/110 (45%), Gaps = 6/110 (5%)
 Frame = +1

Query: 197 YVHRDIKPDNILMDMNGHIRLADFGSCLKLMEDGTVQSSVAVGTPDYISPEILQAMEDGK 256
           YVHRD+   N L+  +  ++++DFG    +      + S     P    P  L+A+   K
Sbjct: 7   YVHRDLATRNCLVGHDLVVKISDFGLARSVHSVDYYRGSEHDAIPIRWMP--LEAILYNK 180

Query: 257 GRYGPECDWWSLGVCMYEML-YGETPFYAESLVETY-----GKIMNHKER 300
             +  + D WS GV ++E+  +   P+Y  +  E       GK++   ER
Sbjct: 181 --FSTQSDVWSFGVVLWEIFAFALQPYYGLTHEEVVRFVKEGKVLACPER 324
>15105
          Length = 367

 Score = 35.8 bits (81), Expect = 0.16,   Method: Composition-based stats.
 Identities = 18/45 (40%), Positives = 26/45 (57%)
 Frame = +1

Query: 1543 NKRRYSFRVPXXXXXXXXXXXXXDPEMRNKLISNPTNFNHIAHMG 1587
            NKRR+SF+                 + R+++IS P+NF+HIAHMG
Sbjct: 199  NKRRFSFK------SREDERSSNKGDRRSRIISPPSNFSHIAHMG 315
>00638
          Length = 1595

 Score = 35.4 bits (80), Expect = 0.20,   Method: Composition-based stats.
 Identities = 14/32 (43%), Positives = 22/32 (68%)
 Frame = +2

Query: 179 RFYLAEMVIAIDSVHQLHYVHRDIKPDNILMD 210
           RFYL E++ A+D  H +  +HRD+KP   L++
Sbjct: 425 RFYLYELMKALDFCHSMGIMHRDVKPSPPLVN 520
>07940
          Length = 1336

 Score = 35.0 bits (79), Expect = 0.30,   Method: Compositional matrix adjust.
 Identities = 25/87 (28%), Positives = 44/87 (50%), Gaps = 2/87 (2%)
 Frame = -3

Query: 198 VHRDIKPDNILMDMNGHIRLADFGSCLKLMEDGTVQSSVAVGTP-DYISPEILQAMEDGK 256
           +HRD+   N+L+     +++ADFG    L +    + +     P  +++PE   A+ D K
Sbjct: 281 IHRDLAARNVLVAEEYVLKIADFGLTRNLQQFDYYRKTTDGRLPVKWMAPE---ALFDRK 111

Query: 257 GRYGPECDWWSLGVCMYEML-YGETPF 282
             Y  + D WS GV ++E+   G  P+
Sbjct: 110 --YTSKSDVWSYGVLLWEIFTLGGNPY 36
>11404
          Length = 563

 Score = 34.3 bits (77), Expect = 0.40,   Method: Compositional matrix adjust.
 Identities = 42/147 (28%), Positives = 66/147 (44%), Gaps = 14/147 (9%)
 Frame = +1

Query: 77  FEILKVIGRGAFGEVAVVKLKNADKVFAMKIL-NKWEMLKRAETACFREERDVLVNGDSK 135
           +EI  +IG+G+FG+V        ++  A+KI+ NK   L +A+      E     + D+K
Sbjct: 145 YEIDSLIGKGSFGQVVKAYDHTDNEQVAIKIIKNKKPFLNQAQIEVKLLEMMNRHDTDNK 324

Query: 136 -WITTL--HYAFQD---------DNNLY-LVMDYYVGGDLLTLLSKFEDRLPEEMARFYL 182
            +I  L  H+ F+            NLY L+ +    G  L L  KF  +L   +     
Sbjct: 325 YYIVRLKRHFMFRSHLCLVFELLSYNLYDLLRNTNFRGVSLNLTRKFAQQLCTALLFLAT 504

Query: 183 AEMVIAIDSVHQLHYVHRDIKPDNILM 209
            EM I          +H D+KP+NIL+
Sbjct: 505 PEMSI----------IHCDLKPENILL 555
>18401
          Length = 463

 Score = 33.9 bits (76), Expect = 0.65,   Method: Compositional matrix adjust.
 Identities = 18/48 (37%), Positives = 26/48 (54%)
 Frame = -3

Query: 235 SVAVGTPDYISPEILQAMEDGKGRYGPECDWWSLGVCMYEMLYGETPF 282
           S  V T  Y +PE++  +E G   +   CD WS+G  M+E+  G T F
Sbjct: 458 STIVSTRHYRAPEVI--LELG---WSHPCDVWSVGCIMFELYTGYTLF 330
>11780
          Length = 1713

 Score = 33.1 bits (74), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 36/158 (22%), Positives = 71/158 (44%), Gaps = 11/158 (6%)
 Frame = +3

Query: 75  EDFEILKVIGRGAFGEV----------AVVKLKNADKVFAMKILNKWEMLKRAETACFRE 124
           +D EI + IG+G FG+V          A+ +LK+ D               R E + F +
Sbjct: 597 QDLEIGEAIGKGDFGDVYKGMYRGQPVAIKQLKDKD---------------RGEQS-FLQ 728

Query: 125 ERDVLVNGDSKWITTLHYAFQDDNNLYLVMDYYVGGDLLTLL-SKFEDRLPEEMARFYLA 183
           E  V+ +     +  L      +  ++LV ++   G+L+  L S+    + ++    +  
Sbjct: 729 EASVMTSLRHDNLVRLIGVVLGET-IFLVTEFMGKGNLVEYLRSRGRSVITKKDQINFAT 905

Query: 184 EMVIAIDSVHQLHYVHRDIKPDNILMDMNGHIRLADFG 221
           +   A++ +     VHRD+   N+L+  +G  +++DFG
Sbjct: 906 DTCAAMEYLESKRLVHRDLAARNVLVHDDGKAKVSDFG 1019
>12068
          Length = 930

 Score = 32.3 bits (72), Expect = 1.5,   Method: Composition-based stats.
 Identities = 13/36 (36%), Positives = 18/36 (50%), Gaps = 8/36 (22%)
 Frame = +2

Query: 1029 CHQCTSLM--------VGLIRQGCSCEVCGFSCHIT 1056
            C  C SL+        + ++  GC CEVCG   HI+
Sbjct: 305  CENCMSLLNCTCHCYTMRVLNDGCQCEVCGLGVHIS 412
>30339
          Length = 384

 Score = 32.3 bits (72), Expect = 1.6,   Method: Composition-based stats.
 Identities = 12/27 (44%), Positives = 19/27 (70%)
 Frame = -2

Query: 71 RLHREDFEILKVIGRGAFGEVAVVKLK 97
          R H  DF  +KV+G+G+FG+V + + K
Sbjct: 86 RFHLHDFNFIKVLGKGSFGKVMLAERK 6
>01106
          Length = 878

 Score = 32.0 bits (71), Expect = 2.0,   Method: Compositional matrix adjust.
 Identities = 37/156 (23%), Positives = 70/156 (44%), Gaps = 13/156 (8%)
 Frame = +3

Query: 67  VKQMRLHREDFEILKVIGRGAFGEVAVVKLKNADKVFAMKILNKWEMLKRAETA------ 120
           VK   L    + +++ +G G F  V +       +  A+K++   +     ETA      
Sbjct: 294 VKNGDLFNGRYHVIRKLGWGHFSTVWLCWDLTCKRFVALKVVKSAQHY--TETALDEVKL 467

Query: 121 --CFREERDVLVNGDSKWITTLH-YAFQDDNNLYLVMDYYV-GGDLLTLL--SKFEDRLP 174
             C RE  DV     +K +  L  +     N  ++ M + V G +LL L+  S ++  +P
Sbjct: 468 LKCVRES-DVADPARAKCVQLLDDFKISGVNGTHVAMVFEVLGYNLLKLIIRSNYQG-IP 641

Query: 175 EEMARFYLAEMVIAIDSVH-QLHYVHRDIKPDNILM 209
               +  + +++  +  +H +   +H DIKP+NIL+
Sbjct: 642 IHNVKLIIRQVLEGLSYMHAKCRIIHTDIKPENILI 749
>31120
          Length = 439

 Score = 31.2 bits (69), Expect = 3.5,   Method: Composition-based stats.
 Identities = 22/68 (32%), Positives = 38/68 (55%), Gaps = 4/68 (5%)
 Frame = +1

Query: 259 YGPE-CDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHK--ERFQFPAQVTD-VSENA 314
           Y P+  D WSLGV ++ ML G+ PF   +L     K++  +  +++ F  ++ D VS NA
Sbjct: 22  YDPKMADAWSLGVILFIMLNGKMPFDDSNL----NKLLEDQRSKKYSFRRKLQDLVSPNA 189

Query: 315 KDLIRRLI 322
           +  +  L+
Sbjct: 190 RSTVSVLL 213
>24037
          Length = 2006

 Score = 31.2 bits (69), Expect = 4.1,   Method: Compositional matrix adjust.
 Identities = 21/53 (39%), Positives = 32/53 (60%)
 Frame = +2

Query: 503 VAEVNHLEQQLEEANSVRRELDDAFRQIKASEKQIKTLQQEREELNKELVQAS 555
           +AE + L  QL     + RELD + RQ  A  +QI+ L +ER+ LNK + +A+
Sbjct: 332 IAERDTLRNQL---TGLERELDASARQSAADSRQIQDLTRERDTLNKHMKKAA 481
>29360
          Length = 363

 Score = 30.4 bits (67), Expect = 6.8,   Method: Compositional matrix adjust.
 Identities = 21/69 (30%), Positives = 38/69 (55%), Gaps = 2/69 (2%)
 Frame = +3

Query: 143 AFQDDNNLYLVMDYYVGGDLLTLL--SKFEDRLPEEMARFYLAEMVIAIDSVHQLHYVHR 200
            FQ  N+  LV +  +  +L   L  +KF+  LP +  R    +++ A+  + QL  +H 
Sbjct: 159 CFQHKNHTCLVFEM-LEQNLYDFLKQNKFQP-LPLKYIRPITQQVLTALRKLKQLGLIHA 332

Query: 201 DIKPDNILM 209
           D+KP+NI++
Sbjct: 333 DLKPENIML 359
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|10946660|ref|NP_067318.1| spermatogenesis associated
5 [Mus musculus]
         (892 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

03022                                                                 260   3e-78
02582                                                                 238   6e-63
01642                                                                 229   4e-60
38672                                                                 189   1e-57
07243                                                                 201   8e-52
23766                                                                 189   3e-48
19129                                                                 174   1e-43
07247                                                                 145   3e-37
00810                                                                 132   6e-31
12235                                                                 129   4e-30
20270                                                                 114   2e-28
25671                                                                  88   2e-20
26408                                                                  74   2e-13
17843                                                                  67   4e-11
02194                                                                  66   7e-11
06766                                                                  60   4e-09
25936                                                                  59   7e-09
14413                                                                  46   6e-05
29846                                                                  45   1e-04
19561                                                                  40   0.003
08000                                                                  30   0.004
01279                                                                  40   0.006
15498                                                                  37   0.026
30736                                                                  34   0.29 
27434                                                                  33   0.48 
12364                                                                  31   2.7  
18971                                                                  30   3.1  
34849                                                                  29   7.3  
>03022
          Length = 2255

 Score =  260 bits (665), Expect(2) = 3e-78,   Method: Compositional matrix adjust.
 Identities = 167/456 (36%), Positives = 249/456 (54%), Gaps = 40/456 (8%)
 Frame = +2

Query: 463  GAQSEVEKRVVASLLTLMDGIGSEGSEGRVLVLGATNRPQALDAALRRPGRFDKEIEIGI 522
            G   ++  R+V+ L + +D +  E  E  V+V+  T+R +A+   LR PGRF  E  +G+
Sbjct: 875  GGSKDMMTRIVSELGSCIDEL-QEKPEN-VVVVATTSRIEAVHRDLRIPGRF-MEKALGM 1045

Query: 523  PNAQDRLDILQKLLRRV---PHLLTKAELLRLANNAHGYVGADLKALCNEAGLHALRRV- 578
            P+   R  +LQ+L  R    PHL    +L  LA    G+V  DL+AL + A   A RRV 
Sbjct: 1046 PDEGSREGLLQRLCSRYTLSPHL----KLKTLARLTPGFVAGDLRALVHGAFSTAFRRVR 1213

Query: 579  -----------LRKQP--NLPDSKVAG-----------MVKITLNDFLQGMNDIRPSAMR 614
                        R+ P   LP + + G            V +T  DF+  +   +P+A R
Sbjct: 1214 NLYRTESAESSTRRHPFPPLPPAHLTGKDIXPQEQDIAAVALTEEDFMGALKKAQPAAKR 1393

Query: 615  EVAIDVPNVSWSDIGGLENIKLKLKQAVEWPLKHPKSFNRMGIQPPKGVLLYGPPGCSKT 674
            E    VP  +W D+G L N++ +LK ++   +  P+  +  G+    G++L GPPGC KT
Sbjct: 1394 EGFATVPTTTWEDVGALSNVRAQLKDSILCRIHDPEVSSAFGLPTNSGIILVGPPGCGKT 1573

Query: 675  MIAKALANESGLNFLAIKGPELMNKYVGESERAVREIFRKARAVAPSIIFFDELDALAVE 734
            ++AKA+ANE+GLNF+ IKGPEL++KYVGESER +RE F KA+A AP +IFFDE+D L   
Sbjct: 1574 LVAKAMANEAGLNFIYIKGPELLDKYVGESERNLREKFDKAQACAPCLIFFDEMDTLCSN 1753

Query: 735  RGSSSGAGNVADRVLAQLLTEMDGIEQLKNVTVLAATNRPDRIDKALMRPGRIDRIIYVP 794
            R ++ G+ NV   V  QLL  MDG  +   V V+ ATN  + +D AL RPGR DR I++ 
Sbjct: 1754 RQNNDGS-NVGKSVTNQLLALMDGCGERSQVYVMGATNIIENVDPALQRPGRFDRKIFIG 1930

Query: 795  LPDAATRREILN--LQFHSMPISNEVDLDELVLQTDTYSGAEIIAVCKEAALLALEENI- 851
            LPD   R +IL    +  S       D+ +L   T+ +SGA++  +  EA+ +AL+E++ 
Sbjct: 1931 LPDTDGRLDILRALTKGGSQRKLESCDMQQLAQDTEGFSGADLKHLVNEASTIALKESMA 2110

Query: 852  ---------KADCIMKRHFTEALSIVTPRIPESLRR 878
                     +   +    FT AL +V P + + +RR
Sbjct: 2111 DQAWREDSHREYVVTGDQFTRALQLVKPSVMKRMRR 2218

 Score = 51.2 bits (121), Expect(2) = 3e-78,   Method: Compositional matrix adjust.
 Identities = 23/78 (29%), Positives = 47/78 (60%)
 Frame = +1

Query: 385 APRGLLLYGPPGTGKTMIARAVANEVGAYVSVINGPEIISKFYGETEARLRQIFAEATLR 444
           A R  LLYGP G+GK  +A  +A ++   +       +IS   G++E R+R +F +A  +
Sbjct: 634 ACRRYLLYGPRGSGKRFLAECIAGQLKLPLLKPKINTLISGVSGDSEQRVRDLFDQAVSQ 813

Query: 445 HPSIIFIDELDALCPKRE 462
            P ++++++++ L P+++
Sbjct: 814 APCVLYLEDIECLAPRQD 867

 Score =  184 bits (466), Expect = 2e-46,   Method: Compositional matrix adjust.
 Identities = 104/270 (38%), Positives = 158/270 (58%), Gaps = 2/270 (0%)
 Frame = +2

Query: 349  VTYDMIGGLNSQLKAIREIIELPLKQPELFKSYGIPAPRGLLLYGPPGTGKTMIARAVAN 408
             T++ +G L++    +++ I   +  PE+  ++G+P   G++L GPPG GKT++A+A+AN
Sbjct: 1418 TTWEDVGALSNVRAQLKDSILCRIHDPEVSSAFGLPTNSGIILVGPPGCGKTLVAKAMAN 1597

Query: 409  EVGAYVSVINGPEIISKFYGETEARLRQIFAEATLRHPSIIFIDELDALCPKREGAQ-SE 467
            E G     I GPE++ K+ GE+E  LR+ F +A    P +IF DE+D LC  R+    S 
Sbjct: 1598 EAGLNFIYIKGPELLDKYVGESERNLREKFDKAQACAPCLIFFDEMDTLCSNRQNNDGSN 1777

Query: 468  VEKRVVASLLTLMDGIGSEGSEGRVLVLGATNRPQALDAALRRPGRFDKEIEIGIPNAQD 527
            V K V   LL LMDG    G   +V V+GATN  + +D AL+RPGRFD++I IG+P+   
Sbjct: 1778 VGKSVTNQLLALMDGC---GERSQVYVMGATNIIENVDPALQRPGRFDRKIFIGLPDTDG 1948

Query: 528  RLDILQKLLRRVPHL-LTKAELLRLANNAHGYVGADLKALCNEAGLHALRRVLRKQPNLP 586
            RLDIL+ L +      L   ++ +LA +  G+ GADLK L NEA   AL+  +  Q    
Sbjct: 1949 RLDILRALTKGGSQRKLESCDMQQLAQDTEGFSGADLKHLVNEASTIALKESMADQAWRE 2128

Query: 587  DSKVAGMVKITLNDFLQGMNDIRPSAMREV 616
            DS    +V  T + F + +  ++PS M+ +
Sbjct: 2129 DSHREYVV--TGDQFTRALQLVKPSVMKRM 2212
>02582
          Length = 1101

 Score =  238 bits (608), Expect = 6e-63,   Method: Compositional matrix adjust.
 Identities = 127/311 (40%), Positives = 185/311 (59%), Gaps = 34/311 (10%)
 Frame = +3

Query: 596 ITLNDFLQGMNDIRPSAMREV--AIDVPNVSWSDIGGLENIKLKLKQAVEWPLKHPKSFN 653
           IT  D    +   +PS  R V   +D  +V W+DIGGL+ +KL+++QAVEWPL +P +F 
Sbjct: 45  ITRADMEAALLTFKPSMQRGVDCIVDARSVPWTDIGGLDLVKLQIRQAVEWPLLYPDTFQ 224

Query: 654 RMGIQPPKGVLLYGPPGCSKTMIAKALANESGLNFLAIKGPELMNKYVGESERAVREIFR 713
            +G+   KGVLLYGPPGC KT +A+A A    + FL++   +L + YVG++E+ + E F+
Sbjct: 225 ALGLPLTKGVLLYGPPGCGKTTLAQAAATACHVTFLSLSCAQLYSPYVGDAEKKISETFQ 404

Query: 714 KARAVAPSIIFFDELDALAVERGSSSGAGNVADRVLAQLLTEMDGI-------------- 759
           KARA+APSI+F DE+DA+  +R  SS    V++RVL+ LL EMDGI              
Sbjct: 405 KARALAPSILFLDEMDAIVGKRSDSSLGSGVSERVLSALLNEMDGIGVRLDDKSDSREME 584

Query: 760 ------------------EQLKNVTVLAATNRPDRIDKALMRPGRIDRIIYVPLPDAATR 801
                                ++V V+AATNRPD +D AL+RPGR+DR+IYVP PD   R
Sbjct: 585 IEGSSDHTPQVRQHAVKEAHDRHVLVVAATNRPDMLDPALLRPGRMDRLIYVPPPDVQGR 764

Query: 802 REILNLQFHSMPISNEVDLDELVLQTDTYSGAEIIAVCKEAALLALEENIKADCIMKRHF 861
            +   +    MP+  +VD+ +L   T  Y+GA+I  +C E  LLAL+E++ A+C+ + HF
Sbjct: 765 LQSFTIHTRKMPLGKDVDVKQLADLTAGYTGADIKTLCNEVGLLALKESMSAECVNQDHF 944

Query: 862 TEALSIVTPRI 872
             A+    P +
Sbjct: 945 LNAIKTRKPSL 977

 Score =  152 bits (383), Expect = 8e-37,   Method: Compositional matrix adjust.
 Identities = 96/259 (37%), Positives = 140/259 (54%), Gaps = 31/259 (11%)
 Frame = +3

Query: 349 VTYDMIGGLNSQLKAIREIIELPLKQPELFKSYGIPAPRGLLLYGPPGTGKTMIARAVAN 408
           V +  IGGL+     IR+ +E PL  P+ F++ G+P  +G+LLYGPPG GKT +A+A A 
Sbjct: 132 VPWTDIGGLDLVKLQIRQAVEWPLLYPDTFQALGLPLTKGVLLYGPPGCGKTTLAQAAAT 311

Query: 409 EVGAYVSVINGPEIISKFYGETEARLRQIFAEATLRHPSIIFIDELDALCPKREGAQ--S 466
                   ++  ++ S + G+ E ++ + F +A    PSI+F+DE+DA+  KR  +   S
Sbjct: 312 ACHVTFLSLSCAQLYSPYVGDAEKKISETFQKARALAPSILFLDEMDAIVGKRSDSSLGS 491

Query: 467 EVEKRVVASLLTLMDGIG-----------------------------SEGSEGRVLVLGA 497
            V +RV+++LL  MDGIG                              E  +  VLV+ A
Sbjct: 492 GVSERVLSALLNEMDGIGVRLDDKSDSREMEIEGSSDHTPQVRQHAVKEAHDRHVLVVAA 671

Query: 498 TNRPQALDAALRRPGRFDKEIEIGIPNAQDRLDILQKLLRRVPHLLTKAELLRLANNAHG 557
           TNRP  LD AL RPGR D+ I +  P+ Q RL       R++P L    ++ +LA+   G
Sbjct: 672 TNRPDMLDPALLRPGRMDRLIYVPPPDVQGRLQSFTIHTRKMP-LGKDVDVKQLADLTAG 848

Query: 558 YVGADLKALCNEAGLHALR 576
           Y GAD+K LCNE GL AL+
Sbjct: 849 YTGADIKTLCNEVGLLALK 905
>01642
          Length = 1406

 Score =  229 bits (583), Expect = 4e-60,   Method: Compositional matrix adjust.
 Identities = 116/250 (46%), Positives = 165/250 (66%), Gaps = 8/250 (3%)
 Frame = -1

Query: 609  RPSAMREVAID-------VPNVSWSDIGGLENIKLKLKQAVEWPLKHPKSFNRMGIQPPK 661
            RPS  R  A+         P   +SDIGG++  K ++++AVE PL H + + ++GI PP+
Sbjct: 1067 RPSPQRLTAVSQCFKLMRSPT*XYSDIGGMDIQKQEVREAVELPLTHFELYKQIGIDPPR 888

Query: 662  GVLLYGPPGCSKTMIAKALANESGLNFLAIKGPELMNKYVGESERAVREIFRKARAVAPS 721
            GVL+YGPPGC KTM+AKA+A+ +   F+ + G E + KY+GE  R VR++FR A+  AP+
Sbjct: 887  GVLMYGPPGCGKTMLAKAVAHHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPA 708

Query: 722  IIFFDELDALAVER-GSSSGAGNVADRVLAQLLTEMDGIEQLKNVTVLAATNRPDRIDKA 780
            IIF DE+DA+A +R  + +GA     R+L +LL +MDG +Q  NV V+ ATNR D +D A
Sbjct: 707  IIFIDEIDAIATKRFDAQTGADREVQRILLELLNQMDGFDQTVNVKVIMATNRADTLDPA 528

Query: 781  LMRPGRIDRIIYVPLPDAATRREILNLQFHSMPISNEVDLDELVLQTDTYSGAEIIAVCK 840
            L+RPGR+DR I  PLPD   +R I +     M IS EVDL++ V + D  SGA+I A+C+
Sbjct: 527  LLRPGRLDRKIEFPLPDRRQKRLIFSTITGKMNISEEVDLEDYVARPDKISGADINAICQ 348

Query: 841  EAALLALEEN 850
            EA + A+ EN
Sbjct: 347  EAGMQAVREN 318

 Score =  162 bits (409), Expect = 7e-40,   Method: Compositional matrix adjust.
 Identities = 89/226 (39%), Positives = 132/226 (58%)
 Frame = -1

Query: 351 YDMIGGLNSQLKAIREIIELPLKQPELFKSYGIPAPRGLLLYGPPGTGKTMIARAVANEV 410
           Y  IGG++ Q + +RE +ELPL   EL+K  GI  PRG+L+YGPPG GKTM+A+AVA+  
Sbjct: 998 YSDIGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAKAVAHHT 819

Query: 411 GAYVSVINGPEIISKFYGETEARLRQIFAEATLRHPSIIFIDELDALCPKREGAQSEVEK 470
            A    + G E + K+ GE    +R +F  A    P+IIFIDE+DA+  KR  AQ+  ++
Sbjct: 818 TAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRFDAQTGADR 639

Query: 471 RVVASLLTLMDGIGSEGSEGRVLVLGATNRPQALDAALRRPGRFDKEIEIGIPNAQDRLD 530
            V   LL L++ +        V V+ ATNR   LD AL RPGR D++IE  +P+ + +  
Sbjct: 638 EVQRILLELLNQMDGFDQTVNVKVIMATNRADTLDPALLRPGRLDRKIEFPLPDRRQKRL 459

Query: 531 ILQKLLRRVPHLLTKAELLRLANNAHGYVGADLKALCNEAGLHALR 576
           I   +  ++ ++  + +L           GAD+ A+C EAG+ A+R
Sbjct: 458 IFSTITGKM-NISEEVDLEDYVARPDKISGADINAICQEAGMQAVR 324
>38672
          Length = 730

 Score =  189 bits (479), Expect(2) = 1e-57,   Method: Compositional matrix adjust.
 Identities = 92/210 (43%), Positives = 142/210 (67%), Gaps = 3/210 (1%)
 Frame = -3

Query: 459 PKREGAQSEVEKRVVASLLTLMDGIGSEGSEGRVLVLGATNRPQALDAALRRPGRFDKEI 518
           PK      EVE+R+V+ LLTLMDG+        V+V+ ATNRP ++DAALRR GRFD+E+
Sbjct: 620 PKERETHGEVERRIVSQLLTLMDGLKQRS---HVIVMAATNRPNSVDAALRRFGRFDREV 450

Query: 519 EIGIPNAQDRLDILQKLLRRVPHLLTKAELLRLANNAHGYVGADLKALCNEAGLHALRR- 577
           +IGIP+A  RL+IL+   + +  L    +L ++A+  HG+VGAD+ ALC+EA L  +R  
Sbjct: 449 DIGIPDATGRLEILRIHTKNMK-LADDVDLEQVASETHGHVGADVAALCSEAALQQIREK 273

Query: 578 --VLRKQPNLPDSKVAGMVKITLNDFLQGMNDIRPSAMREVAIDVPNVSWSDIGGLENIK 635
             ++  + +  D++V   + +T++DF   +    PSA+RE  ++VPNVSW D+GGLEN+K
Sbjct: 272 MDLIDLEDDTIDAEVLDSLAVTMDDFRWALGKSNPSALRETCVEVPNVSWEDVGGLENVK 93

Query: 636 LKLKQAVEWPLKHPKSFNRMGIQPPKGVLL 665
            +L++ V++P++HP+ F + G+ P KGVL 
Sbjct: 92  KELQELVQYPVEHPEKFLKFGMTPSKGVLF 3

 Score = 53.9 bits (128), Expect(2) = 1e-57,   Method: Compositional matrix adjust.
 Identities = 25/41 (60%), Positives = 31/41 (75%)
 Frame = -1

Query: 422 IISKFYGETEARLRQIFAEATLRHPSIIFIDELDALCPKRE 462
           I+SK  GE+E+ LR+ F EA    P+IIFIDELDA+ PKRE
Sbjct: 730 IMSKLAGESESNLRKAFEEAEKNAPAIIFIDELDAIAPKRE 608

 Score = 99.8 bits (247), Expect(2) = 5e-28,   Method: Compositional matrix adjust.
 Identities = 48/110 (43%), Positives = 76/110 (69%)
 Frame = -3

Query: 742 GNVADRVLAQLLTEMDGIEQLKNVTVLAATNRPDRIDKALMRPGRIDRIIYVPLPDAATR 801
           G V  R+++QLLT MDG++Q  +V V+AATNRP+ +D AL R GR DR + + +PDA  R
Sbjct: 599 GEVERRIVSQLLTLMDGLKQRSHVIVMAATNRPNSVDAALRRFGRFDREVDIGIPDATGR 420

Query: 802 REILNLQFHSMPISNEVDLDELVLQTDTYSGAEIIAVCKEAALLALEENI 851
            EIL +   +M ++++VDL+++  +T  + GA++ A+C EAAL  + E +
Sbjct: 419 LEILRIHTKNMKLADDVDLEQVASETHGHVGADVAALCSEAALQQIREKM 270

 Score = 43.9 bits (102), Expect(2) = 5e-28,   Method: Compositional matrix adjust.
 Identities = 21/40 (52%), Positives = 29/40 (72%)
 Frame = -1

Query: 696 LMNKYVGESERAVREIFRKARAVAPSIIFFDELDALAVER 735
           +M+K  GESE  +R+ F +A   AP+IIF DELDA+A +R
Sbjct: 730 IMSKLAGESESNLRKAFEEAEKNAPAIIFIDELDAIAPKR 611
>07243
          Length = 1112

 Score =  201 bits (512), Expect = 8e-52,   Method: Compositional matrix adjust.
 Identities = 104/252 (41%), Positives = 159/252 (63%), Gaps = 1/252 (0%)
 Frame = +1

Query: 619 DVPNVSWSDIGGLENIKLKLKQAVEWPLKHPKSFNRMGIQPPKGVLLYGPPGCSKTMIAK 678
           D  +V++S IGGL     +L++ +E PL +P+ F R+GI PPKG LLYGPPG  KT++A+
Sbjct: 184 DPGDVTYSAIGGLTEQIRELREVIELPLLNPELFLRVGITPPKGCLLYGPPGTGKTLLAR 363

Query: 679 ALANESGLNFLAIKGPELMNKYVGESERAVREIFRKARAVAPSIIFFDELDALAVERGSS 738
           A+A++   NFL +    +++KY+GES R +RE+F  AR   P IIF DE+DA+   R S 
Sbjct: 364 AVASQLDANFLKVVSSAIVDKYIGESARLIREMFNYARDHQPCIIFMDEIDAIGGRRFSE 543

Query: 739 -SGAGNVADRVLAQLLTEMDGIEQLKNVTVLAATNRPDRIDKALMRPGRIDRIIYVPLPD 797
            + A     R L +LL +MDG + L  V ++ ATNRPD +D AL+RPGR+DR I +PLP+
Sbjct: 544 GTSADREIQRTLMELLNQMDGFDSLGQVKMIMATNRPDTLDPALLRPGRLDRKIEIPLPN 723

Query: 798 AATRREILNLQFHSMPISNEVDLDELVLQTDTYSGAEIIAVCKEAALLALEENIKADCIM 857
              R EIL +    +    E+D + +V  +D ++GA++  VC EA L A+    + + ++
Sbjct: 724 EQARLEILKIHALIIAKHGEIDYEAIVKLSDNFNGADLRNVCTEAGLFAIRA--EREYVI 897

Query: 858 KRHFTEALSIVT 869
           +  F +A+  V+
Sbjct: 898 QEDFMKAVRKVS 933

 Score =  186 bits (471), Expect = 5e-47,   Method: Compositional matrix adjust.
 Identities = 113/273 (41%), Positives = 166/273 (60%), Gaps = 11/273 (4%)
 Frame = +1

Query: 349 VTYDMIGGLNSQLKAIREIIELPLKQPELFKSYGIPAPRGLLLYGPPGTGKTMIARAVAN 408
           VTY  IGGL  Q++ +RE+IELPL  PELF   GI  P+G LLYGPPGTGKT++ARAVA+
Sbjct: 196 VTYSAIGGLTEQIRELREVIELPLLNPELFLRVGITPPKGCLLYGPPGTGKTLLARAVAS 375

Query: 409 EVGAYVSVINGPEIISKFYGETEARLRQIFAEATLRHPSIIFIDELDALCPKR--EGAQS 466
           ++ A    +    I+ K+ GE+   +R++F  A    P IIF+DE+DA+  +R  EG  +
Sbjct: 376 QLDANFLKVVSSAIVDKYIGESARLIREMFNYARDHQPCIIFMDEIDAIGGRRFSEGTSA 555

Query: 467 EVE-KRVVASLLTLMDGIGSEGSEGRVLVLGATNRPQALDAALRRPGRFDKEIEIGIPNA 525
           + E +R +  LL  MDG     S G+V ++ ATNRP  LD AL RPGR D++IEI +PN 
Sbjct: 556 DREIQRTLMELLNQMDGF---DSLGQVKMIMATNRPDTLDPALLRPGRLDRKIEIPLPNE 726

Query: 526 QDRLDILQKLLRRVPHLLTKAE--------LLRLANNAHGYVGADLKALCNEAGLHALRR 577
           Q RL+IL+       H L  A+        +++L++N   + GADL+ +C EAGL A+R 
Sbjct: 727 QARLEILKI------HALIIAKHGEIDYEAIVKLSDN---FNGADLRNVCTEAGLFAIR- 876

Query: 578 VLRKQPNLPDSKVAGMVKITLNDFLQGMNDIRP 610
              ++  + +  +  + K++ N  L+   D +P
Sbjct: 877 -AEREYVIQEDFMKAVRKVSDNKKLESKLDYKP 972
>23766
          Length = 1463

 Score =  189 bits (481), Expect = 3e-48,   Method: Compositional matrix adjust.
 Identities = 94/201 (46%), Positives = 133/201 (66%), Gaps = 1/201 (0%)
 Frame = +1

Query: 650 KSFNRMGIQPPKGVLLYGPPGCSKTMIAKALANESGLNFLAIKGPELMNKYVGESERAVR 709
           +   R G Q PKGV+LYGPPG  KT++AKA+AN++   FL + G EL+ KY+G+  + VR
Sbjct: 124 RVLRRDGNQAPKGVILYGPPGTGKTLLAKAVANQTSATFLRVVGSELIQKYLGDGPKLVR 303

Query: 710 EIFRKARAVAPSIIFFDELDALAVER-GSSSGAGNVADRVLAQLLTEMDGIEQLKNVTVL 768
           E+FR A   APSI+F DE+DA+  +R  S+SG      R + +LL ++DG +   +V V+
Sbjct: 304 ELFRVAEEHAPSIVFIDEIDAVGTKRYESNSGGEREIQRTMLELLNQLDGFDSRGDVKVI 483

Query: 769 AATNRPDRIDKALMRPGRIDRIIYVPLPDAATRREILNLQFHSMPISNEVDLDELVLQTD 828
            ATNR + +D AL+RPGRIDR I  PLPD  T+R I  +    M ++ +V++D+ V+  D
Sbjct: 484 MATNRIETLDPALIRPGRIDRKIEFPLPDEKTKRRIFTIHTSRMTLAGDVNIDDYVMSKD 663

Query: 829 TYSGAEIIAVCKEAALLALEE 849
             SGA+I A+C EA LLAL E
Sbjct: 664 DLSGADIKAICTEAGLLALRE 726

 Score =  142 bits (359), Expect(2) = 4e-40,   Method: Compositional matrix adjust.
 Identities = 84/207 (40%), Positives = 122/207 (58%), Gaps = 7/207 (3%)
 Frame = +1

Query: 377 LFKSYGIPAPRGLLLYGPPGTGKTMIARAVANEVGAYVSVINGPEIISKFYGETEARLRQ 436
           + +  G  AP+G++LYGPPGTGKT++A+AVAN+  A    + G E+I K+ G+    +R+
Sbjct: 127 VLRRDGNQAPKGVILYGPPGTGKTLLAKAVANQTSATFLRVVGSELIQKYLGDGPKLVRE 306

Query: 437 IFAEATLRHPSIIFIDELDALCPKREGAQSEVEKRVVASLLTLMDGIGSEGSEGRVLVLG 496
           +F  A    PSI+FIDE+DA+  KR  + S  E+ +  ++L L++ +    S G V V+ 
Sbjct: 307 LFRVAEEHAPSIVFIDEIDAVGTKRYESNSGGEREIQRTMLELLNQLDGFDSRGDVKVIM 486

Query: 497 ATNRPQALDAALRRPGRFDKEIEIGIPNAQDRLDILQKLLRRVPHLLTKAELLRLANNAH 556
           ATNR + LD AL RPGR D++IE  +P+        +K  RR+  + T    L    N  
Sbjct: 487 ATNRIETLDPALIRPGRIDRKIEFPLPD--------EKTKRRIFTIHTSRMTLAGDVNID 642

Query: 557 GYV-------GADLKALCNEAGLHALR 576
            YV       GAD+KA+C EAGL ALR
Sbjct: 643 DYVMSKDDLSGADIKAICTEAGLLALR 723

 Score = 41.6 bits (96), Expect(2) = 4e-40,   Method: Composition-based stats.
 Identities = 17/34 (50%), Positives = 25/34 (73%)
 Frame = +2

Query: 350 TYDMIGGLNSQLKAIREIIELPLKQPELFKSYGI 383
           TY  IGGL++Q++ I+E +ELPL  PE ++  GI
Sbjct: 47  TYADIGGLDTQIQEIKESVELPLTHPEYYEEMGI 148

 Score = 41.2 bits (95), Expect = 0.002,   Method: Composition-based stats.
 Identities = 17/41 (41%), Positives = 28/41 (68%)
 Frame = +2

Query: 621 PNVSWSDIGGLENIKLKLKQAVEWPLKHPKSFNRMGIQPPK 661
           P  +++DIGGL+    ++K++VE PL HP+ +  MGI+  K
Sbjct: 38  PQETYADIGGLDTQIQEIKESVELPLTHPEYYEEMGIKHQK 160
>19129
          Length = 1020

 Score =  174 bits (441), Expect = 1e-43,   Method: Compositional matrix adjust.
 Identities = 87/198 (43%), Positives = 126/198 (63%), Gaps = 2/198 (1%)
 Frame = +1

Query: 606 NDIRPSAMREVAIDVPNVSWSDIGGLENIKLKLKQAVEWPLKHPKSFNRMGIQPPKGVLL 665
           N + P     +   VP+ ++  +GGL+    ++K+ +E P+KHP+ F  +GI  PKGVLL
Sbjct: 427 NKVDPLVSLMMVEKVPDSTYEMVGGLDKQIKEIKEVIELPVKHPELFEALGIAQPKGVLL 606

Query: 666 YGPPGCSKTMIAKALANESGLNFLAIKGPELMNKYVGESERAVREIFRKARAVAPSIIFF 725
           YGPPG  KT++A+A+A+ +   F+ + G EL+ K++GE  R VRE+F  AR  APSIIF 
Sbjct: 607 YGPPGTGKTLLARAVAHHTECTFIRVSGSELVQKFIGEGSRMVRELFVMAREHAPSIIFM 786

Query: 726 DELDALAVER--GSSSGAGNVADRVLAQLLTEMDGIEQLKNVTVLAATNRPDRIDKALMR 783
           DE+D++   R  G S G   V  R + +LL ++DG E  +N+ V+ ATNR D +D AL+R
Sbjct: 787 DEIDSIGSSRLEGGSGGDSEV-QRTMLELLNQLDGFEPKQNIKVIMATNRIDILDSALLR 963

Query: 784 PGRIDRIIYVPLPDAATR 801
           PGRIDR I  P P+   R
Sbjct: 964 PGRIDRKIEFPPPNEEAR 1017

 Score =  164 bits (416), Expect = 1e-40,   Method: Compositional matrix adjust.
 Identities = 86/184 (46%), Positives = 122/184 (66%), Gaps = 4/184 (2%)
 Frame = +1

Query: 350 TYDMIGGLNSQLKAIREIIELPLKQPELFKSYGIPAPRGLLLYGPPGTGKTMIARAVANE 409
           TY+M+GGL+ Q+K I+E+IELP+K PELF++ GI  P+G+LLYGPPGTGKT++ARAVA+ 
Sbjct: 481 TYEMVGGLDKQIKEIKEVIELPVKHPELFEALGIAQPKGVLLYGPPGTGKTLLARAVAHH 660

Query: 410 VGAYVSVINGPEIISKFYGETEARLRQIFAEATLRHPSIIFIDELDALCPKR----EGAQ 465
                  ++G E++ KF GE    +R++F  A    PSIIF+DE+D++   R     G  
Sbjct: 661 TECTFIRVSGSELVQKFIGEGSRMVRELFVMAREHAPSIIFMDEIDSIGSSRLEGGSGGD 840

Query: 466 SEVEKRVVASLLTLMDGIGSEGSEGRVLVLGATNRPQALDAALRRPGRFDKEIEIGIPNA 525
           SEV+ R +  LL  +DG   + +   + V+ ATNR   LD+AL RPGR D++IE   PN 
Sbjct: 841 SEVQ-RTMLELLNQLDGFEPKQN---IKVIMATNRIDILDSALLRPGRIDRKIEFPPPNE 1008

Query: 526 QDRL 529
           + RL
Sbjct: 1009EARL 1020
>07247
          Length = 1753

 Score =  145 bits (367), Expect(2) = 3e-37,   Method: Compositional matrix adjust.
 Identities = 80/204 (39%), Positives = 127/204 (62%), Gaps = 3/204 (1%)
 Frame = -2

Query: 669  PGCSKTMIAKALANESGLNFLAIKGPELMNKYVGESERAVREIFRKARAVAPSIIFFDEL 728
            PG  KT++A+A+A++   NFL +    +++KY+GES R +RE+F  AR   P IIF DE+
Sbjct: 1407 PGTGKTLLARAVASQLDCNFLKVVSSAIVDKYIGESARLIREMFAFARDHEPCIIFMDEI 1228

Query: 729  DALAVERGSS-SGAGNVADRVLAQLLTEMDGIEQLKNVTVLAATNRPDRIDKALMRPGRI 787
            DA+   R S  + A     R L +LL +MDG + L  V ++ ATNRPD +D AL+RPGR+
Sbjct: 1227 DAIGGRRFSEGTSADREIQRTLMELLNQMDGFDALGQVKMIMATNRPDTLDPALLRPGRL 1048

Query: 788  DRIIYVPLPDAATRREILNLQFHSMPISN--EVDLDELVLQTDTYSGAEIIAVCKEAALL 845
            DR I + LP+   R EIL +  H+ PI+   E+D + +V  ++ ++GA++  VC EA + 
Sbjct: 1047 DRKIEISLPNEQARLEILKI--HANPIAKHGEIDWEAVVKLSEDFNGADLRNVCTEAGMF 874

Query: 846  ALEENIKADCIMKRHFTEALSIVT 869
            A+    + D +++  F +A+  V+
Sbjct: 873  AIRA--ERDYVIEEDFMKAVRKVS 808

 Score = 28.9 bits (63), Expect(2) = 3e-37,   Method: Compositional matrix adjust.
 Identities = 11/21 (52%), Positives = 14/21 (66%)
 Frame = -3

Query: 649  PKSFNRMGIQPPKGVLLYGPP 669
            P++    G  PPKG LL+GPP
Sbjct: 1466 PRAVPACGHHPPKGCLLFGPP 1404

 Score =  124 bits (310), Expect(2) = 7e-36,   Method: Compositional matrix adjust.
 Identities = 74/187 (39%), Positives = 115/187 (61%), Gaps = 5/187 (2%)
 Frame = -2

Query: 395  PGTGKTMIARAVANEVGAYVSVINGPEIISKFYGETEARLRQIFAEATLRHPSIIFIDEL 454
            PGTGKT++ARAVA+++      +    I+ K+ GE+   +R++FA A    P IIF+DE+
Sbjct: 1407 PGTGKTLLARAVASQLDCNFLKVVSSAIVDKYIGESARLIREMFAFARDHEPCIIFMDEI 1228

Query: 455  DALCPKR--EGAQSEVE-KRVVASLLTLMDGIGSEGSEGRVLVLGATNRPQALDAALRRP 511
            DA+  +R  EG  ++ E +R +  LL  MDG     + G+V ++ ATNRP  LD AL RP
Sbjct: 1227 DAIGGRRFSEGTSADREIQRTLMELLNQMDGF---DALGQVKMIMATNRPDTLDPALLRP 1057

Query: 512  GRFDKEIEIGIPNAQDRLDILQKLLRRVPHL--LTKAELLRLANNAHGYVGADLKALCNE 569
            GR D++IEI +PN Q RL+IL+     +     +    +++L+ +   + GADL+ +C E
Sbjct: 1056 GRLDRKIEISLPNEQARLEILKIHANPIAKHGEIDWEAVVKLSED---FNGADLRNVCTE 886

Query: 570  AGLHALR 576
            AG+ A+R
Sbjct: 885  AGMFAIR 865

 Score = 46.2 bits (108), Expect(2) = 7e-36,   Method: Compositional matrix adjust.
 Identities = 19/35 (54%), Positives = 27/35 (77%)
 Frame = -1

Query: 349  VTYDMIGGLNSQLKAIREIIELPLKQPELFKSYGI 383
            +T++ IGGL  Q++ +RE+IELPL  PELF+  GI
Sbjct: 1543 ITFNQIGGLGEQVRELREVIELPLLNPELFQRVGI 1439
>00810
          Length = 1431

 Score =  132 bits (332), Expect = 6e-31,   Method: Compositional matrix adjust.
 Identities = 83/229 (36%), Positives = 129/229 (56%), Gaps = 3/229 (1%)
 Frame = -3

Query: 631  LENIKLKLKQAVEWPLKHPKSFNRMGI-QPPKGVLLYGPPGCSKTMIAKALANESGLNFL 689
            LE++   +K+ V  P K    F    + QPPKGVLL+GPPGC KTMIAKA A  +G  F+
Sbjct: 1429 LEDVIQDVKETVILPFKRADLFRHSSLLQPPKGVLLHGPPGCGKTMIAKATAKAAGARFI 1250

Query: 690  AIKGPELMNKYVGESERAVREIFRKARAVAPSIIFFDELDALAVERGSSSGAGNVADRVL 749
             ++   L++K+ GES++    +F  A  + P+IIF DE+D+    R S+         + 
Sbjct: 1249 NLQVSSLVDKWYGESQKRAEAVFSLAIKLQPTIIFIDEIDSFLRSRTSTDHEATAM--IK 1076

Query: 750  AQLLTEMDGIEQLKN--VTVLAATNRPDRIDKALMRPGRIDRIIYVPLPDAATRREILNL 807
             Q ++  DG+    +  V V+ ATNRP  +D A++R  R+  + ++ LP  A RR I NL
Sbjct: 1075 TQFMSFWDGLMTDPDCRVMVMGATNRPQDVDAAILR--RMPSMFHIGLPGPAQRRSIFNL 902

Query: 808  QFHSMPISNEVDLDELVLQTDTYSGAEIIAVCKEAALLALEENIKADCI 856
                  I + ++ DEL   TD +SG++I  VC+ AA+  + E I+ + +
Sbjct: 901  ILSKERI-DALNYDELAEMTDGFSGSDIREVCRAAAVATVHEFIQEEVV 758

 Score =  122 bits (306), Expect = 7e-28,   Method: Compositional matrix adjust.
 Identities = 80/251 (31%), Positives = 131/251 (52%), Gaps = 6/251 (2%)
 Frame = -3

Query: 357  LNSQLKAIREIIELPLKQPELFK-SYGIPAPRGLLLYGPPGTGKTMIARAVANEVGAYVS 415
            L   ++ ++E + LP K+ +LF+ S  +  P+G+LL+GPPG GKTMIA+A A   GA   
Sbjct: 1429 LEDVIQDVKETVILPFKRADLFRHSSLLQPPKGVLLHGPPGCGKTMIAKATAKAAGARFI 1250

Query: 416  VINGPEIISKFYGETEARLRQIFAEATLRHPSIIFIDELDALCPKREGAQSEVEKRVVAS 475
             +    ++ K+YGE++ R   +F+ A    P+IIFIDE+D+    R     E    +   
Sbjct: 1249 NLQVSSLVDKWYGESQKRAEAVFSLAIKLQPTIIFIDEIDSFLRSRTSTDHEATAMIKTQ 1070

Query: 476  LLTLMDGIGSEGSEGRVLVLGATNRPQALDAALRRPGRFDKEIEIGIPNAQDRLDILQKL 535
             ++  DG+ ++  + RV+V+GATNRPQ +DAA+ R  R      IG+P    R  I   +
Sbjct: 1069 FMSFWDGLMTD-PDCRVMVMGATNRPQDVDAAILR--RMPSMFHIGLPGPAQRRSIFNLI 899

Query: 536  LRRVPHLLTKAELLRLANNAHGYVGADLKALCNEAGLHALR-----RVLRKQPNLPDSKV 590
            L +    +       LA    G+ G+D++ +C  A +  +       V+R   N  D + 
Sbjct: 898  LSK--ERIDALNYDELAEMTDGFSGSDIREVCRAAAVATVHEFIQEEVVRGDNNPEDDR- 728

Query: 591  AGMVKITLNDF 601
             G+  +T+ D 
Sbjct: 727  -GLRNLTMRDL 698
>12235
          Length = 1749

 Score =  129 bits (325), Expect = 4e-30,   Method: Compositional matrix adjust.
 Identities = 78/192 (40%), Positives = 108/192 (56%), Gaps = 5/192 (2%)
 Frame = +1

Query: 683 ESGLNFLAIKGPELMNKYVGESERAVREIFRKARAVAPSIIFFDELDALAVER-GSSSGA 741
           E+ + F+ + G E +  +VG     VR++F  AR  AP I+F DE+DA+  +R G + G 
Sbjct: 1   EANVPFITVSGSEFLEMFVGVGPSRVRDMFATARKNAPCILFVDEIDAVGRKRSGRNFGG 180

Query: 742 GNVADRVLAQLLTEMDGIEQLKNVTVLAATNRPDRIDKALMRPGRIDRIIYVPLPDAATR 801
            +  +  L QLL EMDG      V VLAATNR D +D AL+RPGR DR I+VPLPD   R
Sbjct: 181 QSEQENTLNQLLVEMDGFNTQTGVVVLAATNRVDILDAALLRPGRFDRQIFVPLPDIKXR 360

Query: 802 REILNLQFHSMPISNEVDLDELVLQ----TDTYSGAEIIAVCKEAALLALEENIKADCIM 857
             I  +  H  P+  EV+ ++L  +    T  +SGA+I  VC EAAL+A  +      I 
Sbjct: 361 ASIFKV--HLDPLKTEVNKNDLARKMAALTPGFSGADIANVCNEAALIAARD--LNTSIH 528

Query: 858 KRHFTEALSIVT 869
             HF +A+  V 
Sbjct: 529 MTHFEQAIERVV 564

 Score =  103 bits (257), Expect = 3e-22,   Method: Compositional matrix adjust.
 Identities = 66/165 (40%), Positives = 94/165 (56%), Gaps = 5/165 (3%)
 Frame = +1

Query: 417 INGPEIISKFYGETEARLRQIFAEATLRHPSIIFIDELDALCPKREG----AQSEVEKRV 472
           ++G E +  F G   +R+R +FA A    P I+F+DE+DA+  KR G     QSE E   
Sbjct: 25  VSGSEFLEMFVGVGPSRVRDMFATARKNAPCILFVDEIDAVGRKRSGRNFGGQSEQEN-T 201

Query: 473 VASLLTLMDGIGSEGSEGRVLVLGATNRPQALDAALRRPGRFDKEIEIGIPNAQDRLDIL 532
           +  LL  MDG  ++     V+VL ATNR   LDAAL RPGRFD++I + +P+ + R  I 
Sbjct: 202 LNQLLVEMDGFNTQTG---VVVLAATNRVDILDAALLRPGRFDRQIFVPLPDIKXRASIF 372

Query: 533 QKLLRRVPHLLTKAELLR-LANNAHGYVGADLKALCNEAGLHALR 576
           +  L  +   + K +L R +A    G+ GAD+  +CNEA L A R
Sbjct: 373 KVHLDPLKTEVNKNDLARKMAALTPGFSGADIANVCNEAALIAAR 507
>20270
          Length = 542

 Score =  114 bits (286), Expect(2) = 2e-28,   Method: Compositional matrix adjust.
 Identities = 62/131 (47%), Positives = 87/131 (66%), Gaps = 2/131 (1%)
 Frame = -3

Query: 387 RGLLLYGPPGTGKTMIARAVANEV--GAYVSVINGPEIISKFYGETEARLRQIFAEATLR 444
           RG+LLYGPPGTGK+ +A+AVA E     + SV +  +++SK+ GE+E  ++ +F  A   
Sbjct: 378 RGILLYGPPGTGKSYLAKAVATEANNSTFFSV-SSSDLVSKWLGESEKLVKTLFQLAREN 202

Query: 445 HPSIIFIDELDALCPKREGAQSEVEKRVVASLLTLMDGIGSEGSEGRVLVLGATNRPQAL 504
            PSIIFIDE+DALC  R   +SE  +R+    L  M G+G++ +   VLVLGATN P  L
Sbjct: 201 QPSIIFIDEVDALCGSRSENESESARRIKTEFLVQMQGVGNDNTG--VLVLGATNIPWTL 28

Query: 505 DAALRRPGRFD 515
           D+A+RR  RF+
Sbjct: 27  DSAIRR--RFE 1

 Score = 30.0 bits (66), Expect(2) = 2e-28,   Method: Composition-based stats.
 Identities = 13/30 (43%), Positives = 19/30 (63%)
 Frame = -1

Query: 349 VTYDMIGGLNSQLKAIREIIELPLKQPELF 378
           V +D + GLN    A++E + LP+K P LF
Sbjct: 488 VRWDDVAGLNGAKDALKEAVILPVKFPHLF 399

 Score = 97.8 bits (242), Expect(2) = 1e-26,   Method: Compositional matrix adjust.
 Identities = 53/128 (41%), Positives = 78/128 (60%), Gaps = 2/128 (1%)
 Frame = -3

Query: 658 QPPKGVLLYGPPGCSKTMIAKALANESG-LNFLAIKGPELMNKYVGESERAVREIFRKAR 716
           +P +G+LLYGPPG  K+ +AKA+A E+    F ++   +L++K++GESE+ V+ +F+ AR
Sbjct: 387 KPWRGILLYGPPGTGKSYLAKAVATEANNSTFFSVSSSDLVSKWLGESEKLVKTLFQLAR 208

Query: 717 AVAPSIIFFDELDALAVERGSSSGAGNVADRVLAQLLTEMDGI-EQLKNVTVLAATNRPD 775
              PSIIF DE+DAL   R  S      A R+  + L +M G+      V VL ATN P 
Sbjct: 207 ENQPSIIFIDEVDALCGSR--SENESESARRIKTEFLVQMQGVGNDNTGVLVLGATNIPW 34

Query: 776 RIDKALMR 783
            +D A+ R
Sbjct: 33  TLDSAIRR 10

 Score = 41.2 bits (95), Expect(2) = 1e-26,   Method: Composition-based stats.
 Identities = 19/42 (45%), Positives = 25/42 (59%)
 Frame = -1

Query: 611 SAMREVAIDVPNVSWSDIGGLENIKLKLKQAVEWPLKHPKSF 652
           SA+R   ++ PNV W D+ GL   K  LK+AV  P+K P  F
Sbjct: 524 SAVRSHVVEKPNVRWDDVAGLNGAKDALKEAVILPVKFPHLF 399
>25671
          Length = 441

 Score = 87.8 bits (216), Expect(2) = 2e-20,   Method: Compositional matrix adjust.
 Identities = 50/107 (46%), Positives = 65/107 (60%), Gaps = 5/107 (4%)
 Frame = +2

Query: 673 KTMIAKALANESGLNFLAIKGPELMNKYVGESERAVREIFRKARAVAPSIIFFDELDALA 732
           KTM+AKA+A E G  F  +    L NKY GESE+ VR +F  A   APS IF DE+D++ 
Sbjct: 8   KTMLAKAVATECGTTFFNVSTSSLANKYRGESEKLVRLLFEMAHFYAPSTIFIDEIDSIC 187

Query: 733 VERGSSSGAGNVADRVLAQLLTEMDGI-----EQLKNVTVLAATNRP 774
            +RGS S     + RV ++LL +MDG+     +  K V VLAATN P
Sbjct: 188 SKRGSDS-EHEASRRVKSELLVQMDGVGVTNDDPSKAVMVLAATNFP 325

 Score = 30.0 bits (66), Expect(2) = 2e-20,   Method: Compositional matrix adjust.
 Identities = 16/39 (41%), Positives = 24/39 (61%)
 Frame = +3

Query: 774 PDRIDKALMRPGRIDRIIYVPLPDAATRREILNLQFHSM 812
           P  ID+AL R  R+++ IY+PLP A  RR +L +    +
Sbjct: 324 PWDIDEALRR--RLEKRIYIPLPSAEGRRVLLEINLREV 434

 Score = 82.4 bits (202), Expect = 7e-16,   Method: Compositional matrix adjust.
 Identities = 50/119 (42%), Positives = 70/119 (58%), Gaps = 4/119 (3%)
 Frame = +2

Query: 397 TGKTMIARAVANEVGAYVSVINGPEIISKFYGETEARLRQIFAEATLRHPSIIFIDELDA 456
           TGKTM+A+AVA E G     ++   + +K+ GE+E  +R +F  A    PS IFIDE+D+
Sbjct: 2   TGKTMLAKAVATECGTTFFNVSTSSLANKYRGESEKLVRLLFEMAHFYAPSTIFIDEIDS 181

Query: 457 LCPKREGAQSEVE--KRVVASLLTLMDGIG--SEGSEGRVLVLGATNRPQALDAALRRP 511
           +C KR G+ SE E  +RV + LL  MDG+G  ++     V+VL ATN P      L  P
Sbjct: 182 ICSKR-GSDSEHEASRRVKSELLVQMDGVGVTNDDPSKAVMVLAATNFPLGHRRGLEAP 355
>26408
          Length = 463

 Score = 73.9 bits (180), Expect = 2e-13,   Method: Composition-based stats.
 Identities = 31/51 (60%), Positives = 42/51 (82%)
 Frame = +1

Query: 364 IREIIELPLKQPELFKSYGIPAPRGLLLYGPPGTGKTMIARAVANEVGAYV 414
           I+E+IELP+K PELF + GI  P+G+LLYGPPGTGKT++ARAVA+    ++
Sbjct: 298 IKEVIELPVKHPELFDALGIAQPKGVLLYGPPGTGKTLLARAVAHHTRVHI 450

 Score = 63.9 bits (154), Expect = 3e-10,   Method: Composition-based stats.
 Identities = 25/48 (52%), Positives = 39/48 (81%)
 Frame = +1

Query: 637 KLKQAVEWPLKHPKSFNRMGIQPPKGVLLYGPPGCSKTMIAKALANES 684
           ++K+ +E P+KHP+ F+ +GI  PKGVLLYGPPG  KT++A+A+A+ +
Sbjct: 295 RIKEVIELPVKHPELFDALGIAQPKGVLLYGPPGTGKTLLARAVAHHT 438
>17843
          Length = 772

 Score = 66.6 bits (161), Expect = 4e-11,   Method: Compositional matrix adjust.
 Identities = 55/191 (28%), Positives = 88/191 (46%), Gaps = 17/191 (8%)
 Frame = +1

Query: 625 WSDIGGLENIKLKL-KQAVEWPLKHPKSFNRMGIQPPKGVLLYGPPGCSKTMIAKALANE 683
           W  +   ENIK +L   A    L   K  N   I   + +LL+GPPG  KT + KALA++
Sbjct: 76  WDSLVFDENIKERLLNYATTTLLFSDKHVNSSIISWNRVILLHGPPGTGKTTLCKALAHK 255

Query: 684 ---------SGLNFLAIKGPELMNKYVGESERAVREIFRKAR--AVAPSI---IFFDELD 729
                    S    + I    L +K+  ES + V ++F++     V P +   +  DE++
Sbjct: 256 LCIRLSHRFSCGQLVEINSHSLFSKWFSESGKLVTKMFQRLHDYMVDPELLVCVLIDEVE 435

Query: 730 ALAVERGSSSGAGNVAD--RVLAQLLTEMDGIEQLKNVTVLAATNRPDRIDKALMRPGRI 787
           +L   R S       +D  RV+  +LT++D +++  N  +L  +N    ID A +    I
Sbjct: 436 SLTAARKSCLNGNEPSDAIRVVNAVLTQIDQLKKFANCLILTTSNITGAIDLAFVDRADI 615

Query: 788 DRIIYVPLPDA 798
            + I  P P A
Sbjct: 616 KQYIGPPTPPA 648

 Score = 50.8 bits (120), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 49/177 (27%), Positives = 85/177 (48%), Gaps = 22/177 (12%)
 Frame = +1

Query: 383 IPAPRGLLLYGPPGTGKTMIARAVANEVGAYVSV---------INGPEIISKFYGETEAR 433
           I   R +LL+GPPGTGKT + +A+A+++   +S          IN   + SK++ E+   
Sbjct: 175 ISWNRVILLHGPPGTGKTTLCKALAHKLCIRLSHRFSCGQLVEINSHSLFSKWFSESGKL 354

Query: 434 LRQIFA--EATLRHPSI---IFIDELDALCPKRE----GAQSEVEKRVVASLLTLMDGIG 484
           + ++F      +  P +   + IDE+++L   R+    G +     RVV ++LT +D + 
Sbjct: 355 VTKMFQRLHDYMVDPELLVCVLIDEVESLTAARKSCLNGNEPSDAIRVVNAVLTQIDQLK 534

Query: 485 SEGSEGRVLVLGATNRPQALDAALRRPGRFDKEIEIGIPN----AQDRLDILQKLLR 537
              +    L+L  +N   A+D A     R D +  IG P      +  L  L +L+R
Sbjct: 535 KFAN---CLILTTSNITGAIDLAF--VDRADIKQYIGPPTPPAIYKIYLSCLNELMR 690
>02194
          Length = 1891

 Score = 65.9 bits (159), Expect = 7e-11,   Method: Compositional matrix adjust.
 Identities = 49/149 (32%), Positives = 69/149 (46%), Gaps = 9/149 (6%)
 Frame = -1

Query: 649  PKSFNRMGIQPPKGVLLYGPPGCSKTMIAKALANESGLNFLAIKGPELMNKYVGESERAV 708
            P+ +   GI   +G LLYGPPGC K+    ALA     N   +   E      G S+  +
Sbjct: 1531 PRWYMDRGIPYRRGYLLYGPPGCGKSSYIMALAGALDYNICVLNLSE-----KGLSDDRL 1367

Query: 709  REIFRKARAVAP--SIIFFDELDALAVERGSS-------SGAGNVADRVLAQLLTEMDGI 759
              +      VAP  SII  +++DA  + R  S        G G +     + LL  +DG+
Sbjct: 1366 NHLL----TVAPEQSIILLEDVDAAFLSRDLSKENPAMYQGMGRL---TFSGLLNALDGV 1208

Query: 760  EQLKNVTVLAATNRPDRIDKALMRPGRID 788
               +   V   TN  DR+D AL+RPGR+D
Sbjct: 1207 ASAEARIVFMTTNYLDRLDPALIRPGRVD 1121

 Score = 65.9 bits (159), Expect = 8e-11,   Method: Compositional matrix adjust.
 Identities = 55/173 (31%), Positives = 83/173 (47%), Gaps = 7/173 (4%)
 Frame = -1

Query: 375  PELFKSYGIPAPRGLLLYGPPGTGKTMIARAVANEVGAYVSVINGPEIISKFYGETEARL 434
            P  +   GIP  RG LLYGPPG GK+    A+A  +   + V+N  E      G ++ RL
Sbjct: 1531 PRWYMDRGIPYRRGYLLYGPPGCGKSSYIMALAGALDYNICVLNLSEK-----GLSDDRL 1367

Query: 435  RQIFAEATLRHPSIIFIDELDALCPKREGAQSE------VEKRVVASLLTLMDGIGSEGS 488
              +   A     SII ++++DA    R+ ++        + +   + LL  +DG+ S  +
Sbjct: 1366 NHLLTVAP--EQSIILLEDVDAAFLSRDLSKENPAMYQGMGRLTFSGLLNALDGVAS--A 1199

Query: 489  EGRVLVLGATNRPQALDAALRRPGRFD-KEIEIGIPNAQDRLDILQKLLRRVP 540
            E R++ +  TN    LD AL RPGR D KE+     + Q    + Q  LR  P
Sbjct: 1198 EARIVFM-TTNYLDRLDPALIRPGRVDMKELVDHCSDYQ----LTQMFLRFYP 1055
>06766
          Length = 976

 Score = 60.1 bits (144), Expect = 4e-09,   Method: Compositional matrix adjust.
 Identities = 34/120 (28%), Positives = 56/120 (46%), Gaps = 24/120 (20%)
 Frame = +2

Query: 786 RIDRIIYVPLPDAATRREILNLQFHSMPISNEVDLDELVLQTDTYSGAEIIAVCKEAALL 845
           R+D++IY+PLPD  +R  IL       P++ EVDL  +   T  +SGA++  +C+ A  L
Sbjct: 2   RLDQLIYIPLPDDKSREAILKANLRKSPLAKEVDLTYIAKVTQGFSGADLTEICQRACKL 181

Query: 846 ALEENIKADC------------------------IMKRHFTEALSIVTPRIPESLRRFYE 881
           A+ + I+A+                         I + HF EA+      + ++  R YE
Sbjct: 182 AIRQAIEAEIRREKDRAENQNSAMDMDEEDPVPEITRAHFEEAMKFARRSVSDNDIRKYE 361
>25936
          Length = 459

 Score = 59.3 bits (142), Expect = 7e-09,   Method: Composition-based stats.
 Identities = 42/134 (31%), Positives = 66/134 (49%), Gaps = 6/134 (4%)
 Frame = +2

Query: 523 PNAQDRLDILQKLLRRVPHLLTKAELLRL-----ANNAHGYVGADLKALCNEAGLHALRR 577
           P+   R +ILQ  L+    +  ++ L RL     A+   G+V  D++ L N A LHA   
Sbjct: 38  PDKAGRQEILQCTLKSHSTVCARSTLERLDLDSVASRTEGFVARDIQTLVNRA-LHAR-- 208

Query: 578 VLRKQPNLPDSKVAGMVKITLNDFLQGMNDIRPSAMREVAIDVP-NVSWSDIGGLENIKL 636
            L   P    S  +  V +   DF   +   +P A+R V +     + WSD+GGLE +K 
Sbjct: 209 -LAATP----SAESNTVILQQTDFDTALEGFKPLAIRNVHLHTSGELGWSDVGGLEGVKS 373

Query: 637 KLKQAVEWPLKHPK 650
            L + ++WP K+P+
Sbjct: 374 SLIETLQWPSKYPE 415
>14413
          Length = 826

 Score = 46.2 bits (108), Expect = 6e-05,   Method: Compositional matrix adjust.
 Identities = 62/232 (26%), Positives = 108/232 (46%), Gaps = 24/232 (10%)
 Frame = +2

Query: 399 KTMIARAVANEVG-------AYVSV--INGPEIISKFYGETEARLRQIFAE----ATLRH 445
           KT + +A+A ++        AY  +  IN   + SK++ E+   + ++F +    AT ++
Sbjct: 2   KTSLCKALAEKLAIRTQNSFAYTHLVEINSHSLFSKWFSESGKLVARLFGKIGELATDKN 181

Query: 446 PSI-IFIDELDALCPKREGAQSEVEK---RVVASLLTLMDGIGSEGSEGRVLVLGATNRP 501
             + + IDE+++L   R    S   +   RVV ++LT +D I +  +   VL+L  +N  
Sbjct: 182 NLVCVLIDEVESLAYARSAMSSNEPRDAMRVVNAVLTQLDEIKACPN---VLILATSNLA 352

Query: 502 QALDAALRRPGRFDKEIEIGIPNAQDRLDILQKLLRRV-PHLLTKAELLRLANNAHGYVG 560
           Q++D A     R D    IG+P+      I + +L  +    + + E L  +   +    
Sbjct: 353 QSIDLAF--LDRADIRQFIGLPDPLAISSIYKSMLTELMVRGIVRTEELETSEADYKITL 526

Query: 561 ADLKALCNEAGLHALRRVLRKQPNLPDSKVAGM------VKITLNDFLQGMN 606
           ++L A  N  GL    R LRK P L  ++           KITL+DFL  M+
Sbjct: 527 SNLAA--NSTGLSG--RTLRKLPLLAHAQHTSRELFEPNQKITLSDFLHAMH 670
>29846
          Length = 451

 Score = 45.4 bits (106), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 20/52 (38%), Positives = 31/52 (59%)
 Frame = +1

Query: 791 IYVPLPDAATRREILNLQFHSMPISNEVDLDELVLQTDTYSGAEIIAVCKEA 842
           I + +P +  RR+I N     +P+++++DLD L   T  Y GA+I AVC  A
Sbjct: 142 ILISVPTSIQRRQIFNFCLRKLPLASDLDLDWLSSVTAGYVGADIKAVCASA 297

 Score = 40.0 bits (92), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 22/54 (40%), Positives = 32/54 (59%)
 Frame = +1

Query: 517 EIEIGIPNAQDRLDILQKLLRRVPHLLTKAELLRLANNAHGYVGADLKALCNEA 570
           EI I +P +  R  I    LR++P L +  +L  L++   GYVGAD+KA+C  A
Sbjct: 139 EILISVPTSIQRRQIFNFCLRKLP-LASDLDLDWLSSVTAGYVGADIKAVCASA 297
>19561
          Length = 474

 Score = 40.4 bits (93), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 27/87 (31%), Positives = 39/87 (44%), Gaps = 5/87 (5%)
 Frame = -1

Query: 374 QPEL---FKSYGIPAPRGLLLYGPPGTGKTMIARAVANEVGAYVSVINGPE--IISKFYG 428
           QPE+      +  P  +  LL GPPG GKT +A  VA   G  V  +N  +   +  F  
Sbjct: 426 QPEVSSELDDFKRPVQKVALLCGPPGLGKTTLAHIVAKHAGYNVVEMNASDDRSVEVFSN 247

Query: 429 ETEARLRQIFAEATLRHPSIIFIDELD 455
           + EA  +          P+ + IDE+D
Sbjct: 246 KIEAATQMRAVMGADPRPNCLIIDEID 166
>08000
          Length = 343

 Score = 30.0 bits (66), Expect(2) = 0.004,   Method: Composition-based stats.
 Identities = 12/33 (36%), Positives = 19/33 (57%)
 Frame = +3

Query: 810 HSMPISNEVDLDELVLQTDTYSGAEIIAVCKEA 842
             MP+  +VD+ +L   T  Y+GA+I  +C E 
Sbjct: 15  QEMPLGKDVDVKQLADLTAGYTGADIKTLCNEG 113

 Score = 28.9 bits (63), Expect(2) = 0.004,   Method: Compositional matrix adjust.
 Identities = 11/35 (31%), Positives = 21/35 (60%)
 Frame = +1

Query: 838 VCKEAALLALEENIKADCIMKRHFTEALSIVTPRI 872
           +  +  LLAL+E++ A+C+ + HF  A+    P +
Sbjct: 118 IVSQVGLLALKESMSAECVNQDHFLNAIKTRKPSL 222

 Score = 30.4 bits (67), Expect = 3.3,   Method: Composition-based stats.
 Identities = 12/21 (57%), Positives = 15/21 (71%)
 Frame = +3

Query: 550 RLANNAHGYVGADLKALCNEA 570
           +LA+   GY GAD+K LCNE 
Sbjct: 51  QLADLTAGYTGADIKTLCNEG 113
>01279
          Length = 2183

 Score = 39.7 bits (91), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 29/79 (36%), Positives = 39/79 (49%), Gaps = 4/79 (5%)
 Frame = -3

Query: 385  APRGLLLYGPPGTGKTMIARAVANEVGAYVSV--INGPEIISKFYGETEARLRQIFAEAT 442
            A R +LL GPPGTGKT IA A+A E+G  V    + G E+ S    +TE  +        
Sbjct: 1920 AGRAVLLAGPPGTGKTAIALAIAQELGNKVPFCPMVGSEVYSSEIKKTEVLMENFRRAIG 1741

Query: 443  LR--HPSIIFIDELDALCP 459
            LR      ++  E+  L P
Sbjct: 1740 LRIKETKEVYEGEVTELTP 1684

 Score = 37.4 bits (85), Expect = 0.030,   Method: Compositional matrix adjust.
 Identities = 46/168 (27%), Positives = 75/168 (44%), Gaps = 7/168 (4%)
 Frame = -3

Query: 661  KGVLLYGPPGCSKTMIAKALANESG--LNFLAIKGPELMNKYVGESERAVREIFRKA--- 715
            + VLL GPPG  KT IA A+A E G  + F  + G E+ +  + ++E  + E FR+A   
Sbjct: 1914 RAVLLAGPPGTGKTAIALAIAQELGNKVPFCPMVGSEVYSSEIKKTE-VLMENFRRAIGL 1738

Query: 716  RAVAPSIIFFDELDALA-VE-RGSSSGAGNVADRVLAQLLTEMDGIEQLKNVTVLAATNR 773
            R      ++  E+  L  VE      G G     V+  L T   G +QLK    +  + +
Sbjct: 1737 RIKETKEVYEGEVTELTPVETENPMGGYGKTVSHVVIGLKT-AKGTKQLKLDPSIYESLQ 1561

Query: 774  PDRIDKALMRPGRIDRIIYVPLPDAATRREILNLQFHSMPISNEVDLD 821
             ++++        +  +IY+     A +R     Q  S   + E DL+
Sbjct: 1560 KEKVE--------VGDVIYIEANSGAVKR-----QGRSDSYATEFDLE 1456
>15498
          Length = 769

 Score = 37.4 bits (85), Expect = 0.026,   Method: Compositional matrix adjust.
 Identities = 22/68 (32%), Positives = 37/68 (54%)
 Frame = -1

Query: 362 KAIREIIELPLKQPELFKSYGIPAPRGLLLYGPPGTGKTMIARAVANEVGAYVSVINGPE 421
           + + E   LPL  P + +    P  + +LL GP G+GK M+  A+ NEVGA +  ++   
Sbjct: 253 RLVTEFGILPLGSPSVHEQ--APLTKSILLAGPRGSGKKMLVHALCNEVGANLFDLSPAN 80

Query: 422 IISKFYGE 429
           +  K+ G+
Sbjct: 79  LAGKYPGK 56
>30736
          Length = 520

 Score = 33.9 bits (76), Expect = 0.29,   Method: Compositional matrix adjust.
 Identities = 31/90 (34%), Positives = 45/90 (50%), Gaps = 5/90 (5%)
 Frame = -2

Query: 339 NSKEQDSQFKVTY-DMIGGLNSQLKAIREIIELPLKQPELFKSYGIPA----PRGLLLYG 393
           N  +   +F V++ D I  L+S      E +E  LK P   + Y +PA    P  L + G
Sbjct: 255 NRVQGKPEFAVSFLDKIYCLSSH-----EAMEKFLKNP---RPYLLPAQPRPPCKLAVLG 100

Query: 394 PPGTGKTMIARAVANEVGAYVSVINGPEII 423
           PP +GKT +   +AN+ GA   V+   EII
Sbjct: 99  PPLSGKTTLCHLLANKYGA--KVLKVEEII 16
>27434
          Length = 472

 Score = 33.1 bits (74), Expect = 0.48,   Method: Compositional matrix adjust.
 Identities = 29/102 (28%), Positives = 44/102 (43%), Gaps = 9/102 (8%)
 Frame = +2

Query: 389 LLLYGPPGTGKTMIARAVANEVG------AYVSVINGPEIISK---FYGETEARLRQIFA 439
           L   GPPG GKT I R++A  +G      A   V +  +I      + G    R+ Q   
Sbjct: 170 LCFVGPPGVGKTSIGRSIATTLGREFHRIALGGVCDQSDIRGHRRTYIGSMPGRIIQGLK 349

Query: 440 EATLRHPSIIFIDELDALCPKREGAQSEVEKRVVASLLTLMD 481
            A   +P +  +DE+D L     G  +       A+LL ++D
Sbjct: 350 SAGTNNP-VFPLDEIDKLSTSLHGDPA-------AALLEVLD 451
>12364
          Length = 431

 Score = 30.8 bits (68), Expect = 2.7,   Method: Composition-based stats.
 Identities = 13/24 (54%), Positives = 16/24 (66%)
 Frame = +3

Query: 315 TKSNTDTFYFISSTTRINLRKICT 338
           TKSNT  + F+ S TR  LR IC+
Sbjct: 297 TKSNTKNYNFLKSHTRNELRSICS 368
>18971
          Length = 787

 Score = 30.4 bits (67), Expect = 3.1,   Method: Compositional matrix adjust.
 Identities = 15/31 (48%), Positives = 18/31 (58%)
 Frame = +3

Query: 144 LALSDKDKEINEEELTGCILRKLDGKIVLPG 174
           L+LS  D    ++ LTGCILR   G  V PG
Sbjct: 105 LSLSGPDHLHPQQALTGCILRSSRGLAVFPG 197
>34849
          Length = 545

 Score = 29.3 bits (64), Expect = 7.3,   Method: Compositional matrix adjust.
 Identities = 18/55 (32%), Positives = 28/55 (50%), Gaps = 8/55 (14%)
 Frame = +1

Query: 116 QKNVGVRAGETIQVQPLLGAVLQAQEMDLALSDKDKEINEEELT--------GCI 162
           QK    R+GET+++  LL   ++  E  L   ++DK ++ EEL         GCI
Sbjct: 205 QKEFKTRSGETVRLVDLLDEGVKRSEAKLIEKERDKVLSAEELKKAKESVAYGCI 369
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|20502976|ref|NP_038558.1| guanine nucleotide-binding
protein, beta-3 subunit [Mus musculus]
         (340 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

30295                                                                 287   4e-78
17266                                                                 244   3e-65
14555                                                                 102   2e-22
17598                                                                  97   1e-20
12806                                                                  95   5e-20
34511                                                                  74   2e-16
00561                                                                  72   1e-15
13335                                                                  78   5e-15
30256                                                                  77   1e-14
02960                                                                  70   2e-12
27465                                                                  70   2e-12
02147                                                                  69   3e-12
19949                                                                  64   1e-10
17602                                                                  63   2e-10
02090                                                                  60   9e-10
21105                                                                  55   4e-08
03156                                                                  55   5e-08
01327                                                                  55   5e-08
26107                                                                  54   6e-08
12574                                                                  54   7e-08
13278                                                                  54   1e-07
03395                                                                  53   2e-07
01805                                                                  52   4e-07
10162                                                                  49   3e-06
37180                                                                  48   5e-06
11493                                                                  47   7e-06
01598                                                                  45   4e-05
19498                                                                  45   5e-05
18981                                                                  45   6e-05
03387                                                                  44   8e-05
31864                                                                  44   8e-05
27806                                                                  44   1e-04
14500                                                                  36   1e-04
12960                                                                  44   1e-04
07665                                                                  43   2e-04
01249                                                                  43   2e-04
10264                                                                  42   3e-04
15780                                                                  42   3e-04
01462                                                                  41   7e-04
03734                                                                  41   8e-04
26939                                                                  40   0.001
19863                                                                  40   0.002
04358                                                                  39   0.003
21921                                                                  37   0.009
15118                                                                  37   0.016
16199                                                                  37   0.016
12841                                                                  36   0.020
34005                                                                  36   0.022
03044                                                                  36   0.024
35607                                                                  36   0.028
31384                                                                  36   0.029
33180                                                                  35   0.030
29912                                                                  34   0.095
15972                                                                  32   0.26 
19140                                                                  32   0.40 
20662                                                                  32   0.49 
04088                                                                  32   0.50 
31054                                                                  31   0.58 
11915                                                                  31   0.72 
12140                                                                  30   0.98 
07781                                                                  30   0.99 
16105                                                                  30   1.1  
00345                                                                  30   1.3  
18320                                                                  30   1.5  
22113                                                                  30   1.6  
27270                                                                  29   2.6  
15337                                                                  29   3.0  
22154                                                                  29   3.2  
12076                                                                  29   3.3  
27525                                                                  28   5.3  
17298                                                                  28   6.6  
25930                                                                  28   7.6  
13983                                                                  27   9.7  
>30295
          Length = 593

 Score =  287 bits (734), Expect = 4e-78,   Method: Compositional matrix adjust.
 Identities = 134/168 (79%), Positives = 148/168 (88%)
 Frame = +2

Query: 3   EMEQLRQEAEQLKKQIADARKACADITLAELVSGLEVVGRVQMRTRRTLRGHLAKIYAMH 62
           E++ LRQE EQLK QI +ARKA  D TLA+  +  + VGR+QMRTRRTLR HLAKIYAMH
Sbjct: 89  ELDALRQETEQLKNQIREARKAAGDTTLAQATASYDSVGRIQMRTRRTLRXHLAKIYAMH 268

Query: 63  WATDSKLLVSASQDGKLIVWDTYTTNKVHAIPLRSSWVMTCAYAPSGNFVACGGLDNMCS 122
           WATDS+ LVSASQDGKLIVWD YTTNKVHAIPLRSSWVMTCAYAPSG +VACGGLDN+CS
Sbjct: 269 WATDSRNLVSASQDGKLIVWDGYTTNKVHAIPLRSSWVMTCAYAPSGGYVACGGLDNICS 448

Query: 123 IYNLKSREGNVKVSRELSAHTGYLSCCRFLDDNNIVTSSGDTTCALWD 170
           IY+LK+REGNV+VSREL  HTGYLSCCRF+DDN IVTSSGD TCALWD
Sbjct: 449 IYSLKTREGNVRVSRELPGHTGYLSCCRFIDDNQIVTSSGDMTCALWD 592
>17266
          Length = 480

 Score =  244 bits (624), Expect = 3e-65,   Method: Compositional matrix adjust.
 Identities = 112/147 (76%), Positives = 129/147 (87%)
 Frame = -1

Query: 190 LAVSPDYKLFISGACDASAKLWDVREGTCRQTFTGHESDINAICFFPNGEAICTGSDDAS 249
           L+++PD + F+SGACDASAKLWDVR+G C+QTF+GHESDINAI +FPNG A  TGSDDA+
Sbjct: 441 LSLAPDMRTFVSGACDASAKLWDVRDGMCKQTFSGHESDINAITYFPNGHAFATGSDDAT 262

Query: 250 CRLFDLRADQELTAYSQESIICGITSVAFSLSGRLLFAGYDDFNCNVWDSLKCERVGILS 309
           CRLFD+RADQE+  YS ++IICGITSVAFS SGRLL  GYDDFNCN+WD LK ER G+L+
Sbjct: 261 CRLFDIRADQEIGMYSHDNIICGITSVAFSKSGRLLLGGYDDFNCNIWDVLKQERTGVLA 82

Query: 310 GHDNRVSCLGVTADGMAVATGSWDSFL 336
           GHDNRVSCLGVT DG AVATGSWDSFL
Sbjct: 81  GHDNRVSCLGVTEDGSAVATGSWDSFL 1

 Score = 42.4 bits (98), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 36/146 (24%), Positives = 65/146 (44%), Gaps = 3/146 (2%)
 Frame = -1

Query: 106 APSGNFVACGGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFLDDNN-IVTSSGDT 164
           AP       G  D    ++++  R+G  K  +  S H   ++   +  + +   T S D 
Sbjct: 432 APDMRTFVSGACDASAKLWDV--RDGMCK--QTFSGHESDINAITYFPNGHAFATGSDDA 265

Query: 165 TCALWDIETGQQKTVFVGHTGDC--MSLAVSPDYKLFISGACDASAKLWDVREGTCRQTF 222
           TC L+DI   Q+  ++      C   S+A S   +L + G  D +  +WDV +       
Sbjct: 264 TCRLFDIRADQEIGMYSHDNIICGITSVAFSKSGRLLLGGYDDFNCNIWDVLKQERTGVL 85

Query: 223 TGHESDINAICFFPNGEAICTGSDDA 248
            GH++ ++ +    +G A+ TGS D+
Sbjct: 84  AGHDNRVSCLGVTEDGSAVATGSWDS 7
>14555
          Length = 627

 Score =  102 bits (254), Expect = 2e-22,   Method: Compositional matrix adjust.
 Identities = 52/94 (55%), Positives = 64/94 (68%)
 Frame = -2

Query: 218 CRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRADQELTAYSQESIICGITSVA 277
           C Q F GHE+DIN + F+P+G+A  TGSDDA+CRLFDLRAD+E+  Y +ESII G  +V 
Sbjct: 623 CVQMFEGHEADINCVRFYPSGDAFATGSDDATCRLFDLRADREVNCYRKESIIFGCNAVD 444

Query: 278 FSLSGRLLFAGYDDFNCNVWDSLKCERVGILSGH 311
           FS+SGRLLF GY        + L  ERVG    H
Sbjct: 443 FSVSGRLLFGGY--------E*LHSERVGRTERH 366

 Score = 65.1 bits (157), Expect = 4e-11,   Method: Compositional matrix adjust.
 Identities = 29/50 (58%), Positives = 37/50 (74%)
 Frame = -3

Query: 290 DDFNCNVWDSLKCERVGILSGHDNRVSCLGVTADGMAVATGSWDSFLKIW 339
           +D+  NVWD+LK  R  IL GHDNRVSCL ++ DG ++ TGSWD  L+IW
Sbjct: 406 NDYTVNVWDALKGMRSTILYGHDNRVSCLRISPDGTSLCTGSWDYTLRIW 257

 Score = 35.8 bits (81), Expect = 0.029,   Method: Compositional matrix adjust.
 Identities = 14/49 (28%), Positives = 28/49 (57%)
 Frame = -3

Query: 205 DASAKLWDVREGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLF 253
           D +  +WD  +G       GH++ ++ +   P+G ++CTGS D + R++
Sbjct: 403 DYTVNVWDALKGMRSTILYGHDNRVSCLRISPDGTSLCTGSWDYTLRIW 257

 Score = 34.7 bits (78), Expect = 0.056,   Method: Compositional matrix adjust.
 Identities = 15/51 (29%), Positives = 25/51 (49%)
 Frame = -3

Query: 161 SGDTTCALWDIETGQQKTVFVGHTGDCMSLAVSPDYKLFISGACDASAKLW 211
           + D T  +WD   G + T+  GH      L +SPD     +G+ D + ++W
Sbjct: 409 TNDYTVNVWDALKGMRSTILYGHDNRVSCLRISPDGTSLCTGSWDYTLRIW 257
>17598
          Length = 875

 Score = 96.7 bits (239), Expect = 1e-20,   Method: Compositional matrix adjust.
 Identities = 67/256 (26%), Positives = 118/256 (46%), Gaps = 14/256 (5%)
 Frame = +1

Query: 48  RRTLRGHLAKIYAMHWATDSKLLVSASQDGKLIVWDTYTTNKVHAIPLRSSWVMTCAYAP 107
           RRTL+GH   +  +  + DS+ ++S+S D  L +WD    N        +   +  A++P
Sbjct: 100 RRTLQGHSHFVSDVSLSADSRYVLSSSWDATLRLWDIKKGNTTRRFISHTRDALAVAFSP 279

Query: 108 SGNFVACGGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFLDDNN---IVTSSGDT 164
               +A GG D    I+N     G  K + + ++H  +++C +F  D     +V++S D 
Sbjct: 280 DNRQIASGGRDKALKIWNT---VGECKFTVDANSHQDWVTCVKFHQDAKSPLVVSASMDK 450

Query: 165 TCALWDIETGQQKTVFVGHTGDCMSLAVSPDYKLFISGACDASAKLWDVREGTCRQTFTG 224
           T  +WD +T   K  FVGH     ++ ++       SG+ D     W+++ G    TF G
Sbjct: 451 TIKVWDNQTMTLKHTFVGHKTQINAIDLALKTYYLASGSKDGIVMTWNIQNG----TFLG 618

Query: 225 H---ESDINAICFFPNGEAICTGSDDA--------SCRLFDLRADQELTAYSQESIICGI 273
               + ++NA+ F PN   +  G+ +           ++ D+RA      +  +      
Sbjct: 619 KIDCDCEVNAVKFSPNKYWLFVGTSEGIQIWDLPNQKKIKDIRASPIDAQHKSQKKSIAC 798

Query: 274 TSVAFSLSGRLLFAGY 289
           TS+A+  SG  LFAG+
Sbjct: 799 TSLAWDASGHTLFAGF 846

 Score = 71.2 bits (173), Expect = 5e-13,   Method: Compositional matrix adjust.
 Identities = 57/240 (23%), Positives = 95/240 (39%), Gaps = 52/240 (21%)
 Frame = +1

Query: 111 FVACGGLDNMCSIYNLKSREGNVK------VSRELSAHTGYLSCCRF-LDDNNIVTSSGD 163
           F+  GG D +  +++L  R+   +        R L  H+ ++S      D   +++SS D
Sbjct: 7   FLIXGGRDKLLIVWDLVPRKDGDEDETWGGPRRTLQGHSHFVSDVSLSADSRYVLSSSWD 186

Query: 164 TTCALWDIETGQQKTVFVGHTGDCMSLAVSPDYK-------------------------- 197
            T  LWDI+ G     F+ HT D +++A SPD +                          
Sbjct: 187 ATLRLWDIKKGNTTRRFISHTRDALAVAFSPDNRQIASGGRDKALKIWNTVGECKFTVDA 366

Query: 198 -------------------LFISGACDASAKLWDVREGTCRQTFTGHESDINAICFFPNG 238
                              L +S + D + K+WD +  T + TF GH++ INAI      
Sbjct: 367 NSHQDWVTCVKFHQDAKSPLVVSASMDKTIKVWDNQTMTLKHTFVGHKTQINAIDLALKT 546

Query: 239 EAICTGSDDASCRLFDLRADQELTAYSQESIICGITSVAFSLSGRLLFAGYDDFNCNVWD 298
             + +GS D     +++   Q  T   +    C + +V FS +   LF G  +    +WD
Sbjct: 547 YYLASGSKDGIVMTWNI---QNGTFLGKIDCDCEVNAVKFSPNKYWLFVGTSE-GIQIWD 714

 Score = 64.7 bits (156), Expect = 5e-11,   Method: Compositional matrix adjust.
 Identities = 39/169 (23%), Positives = 76/169 (44%), Gaps = 2/169 (1%)
 Frame = +1

Query: 174 GQQKTVFVGHTGDCMSLAVSPDYKLFISGACDASAKLWDVREGTCRQTFTGHESDINAIC 233
           G  +    GH+     +++S D +  +S + DA+ +LWD+++G   + F  H  D  A+ 
Sbjct: 91  GGPRRTLQGHSHFVSDVSLSADSRYVLSSSWDATLRLWDIKKGNTTRRFISHTRDALAVA 270

Query: 234 FFPNGEAICTGSDDASCRLFDLRADQELTAYSQESIICGITSVAFSLSGR--LLFAGYDD 291
           F P+   I +G  D + ++++   + + T     S    +T V F    +  L+ +   D
Sbjct: 271 FSPDNRQIASGGRDKALKIWNTVGECKFTV-DANSHQDWVTCVKFHQDAKSPLVVSASMD 447

Query: 292 FNCNVWDSLKCERVGILSGHDNRVSCLGVTADGMAVATGSWDSFLKIWN 340
               VWD+          GH  +++ + +      +A+GS D  +  WN
Sbjct: 448 KTIKVWDNQTMTLKHTFVGHKTQINAIDLALKTYYLASGSKDGIVMTWN 594
>12806
          Length = 961

 Score = 94.7 bits (234), Expect = 5e-20,   Method: Compositional matrix adjust.
 Identities = 63/193 (32%), Positives = 96/193 (49%), Gaps = 6/193 (3%)
 Frame = +3

Query: 48  RRTLRGHLAKIYAMHWATDSKLLVSASQDGKLIVWDTYTTNKVHAIPLRSSWVMTCAYAP 107
           R+TL GH   I  +  + DS+  +S+S D  L +WD    +        +  V+T A++P
Sbjct: 144 RKTLTGHSHFISDLALSADSRFALSSSWDATLRLWDIKKGSTTSRFINHTRDVLTVAFSP 323

Query: 108 SGNFVACGGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFLDDNN---IVTSSGDT 164
               +A GG D    I+N+    G  K + + +AHT +++C RF  D     +V++S D 
Sbjct: 324 DNRQIASGGRDKNLKIWNIM---GECKYTVDANAHTDWVTCVRFHQDTKNPIVVSASNDK 494

Query: 165 TCALWDIETGQQKTVFVGHTGDCMSLAVSPDYKLFISGACDASAKLWDVREGTCRQTFTG 224
           T  +WD  T   K  FVGH     +L +S +Y   +SG+ D  A  W+V EG    +F G
Sbjct: 495 TIKVWDNHTMTLKNTFVGHKAQITALDMSTNY--LVSGSKDGIAMTWNVAEG----SFVG 656

Query: 225 H---ESDINAICF 234
               +  INAI F
Sbjct: 657 KIDCDDQINAIKF 695

 Score = 64.7 bits (156), Expect = 5e-11,   Method: Compositional matrix adjust.
 Identities = 43/155 (27%), Positives = 80/155 (51%), Gaps = 11/155 (7%)
 Frame = +3

Query: 111 FVACGGLDNMCSIYNL-KSREGNVK----VSRE-LSAHTGYLSCCRFLDDNNI-VTSSGD 163
           F+  GG DN   +++L   ++G+      V R+ L+ H+ ++S      D+   ++SS D
Sbjct: 51  FLISGGRDNNIIVWDL*PKKDGDEDQTWGVPRKTLTGHSHFISDLALSADSRFALSSSWD 230

Query: 164 TTCALWDIETGQQKTVFVGHTGDCMSLAVSPDYKLFISGACDASAKLWDVREGTCRQTF- 222
            T  LWDI+ G   + F+ HT D +++A SPD +   SG  D + K+W++  G C+ T  
Sbjct: 231 ATLRLWDIKKGSTTSRFINHTRDVLTVAFSPDNRQIASGGRDKNLKIWNIM-GECKYTVD 407

Query: 223 -TGHESDINAICFFPN--GEAICTGSDDASCRLFD 254
              H   +  + F  +     + + S+D + +++D
Sbjct: 408 ANAHTDWVTCVRFHQDTKNPIVVSASNDKTIKVWD 512

 Score = 64.7 bits (156), Expect = 5e-11,   Method: Compositional matrix adjust.
 Identities = 38/169 (22%), Positives = 78/169 (46%), Gaps = 2/169 (1%)
 Frame = +3

Query: 174 GQQKTVFVGHTGDCMSLAVSPDYKLFISGACDASAKLWDVREGTCRQTFTGHESDINAIC 233
           G  +    GH+     LA+S D +  +S + DA+ +LWD+++G+    F  H  D+  + 
Sbjct: 135 GVPRKTLTGHSHFISDLALSADSRFALSSSWDATLRLWDIKKGSTTSRFINHTRDVLTVA 314

Query: 234 FFPNGEAICTGSDDASCRLFDLRADQELTAYSQESIICGITSVAFSLSGR--LLFAGYDD 291
           F P+   I +G  D + +++++  + + T  +       +T V F    +  ++ +  +D
Sbjct: 315 FSPDNRQIASGGRDKNLKIWNIMGECKYTVDANAHTDW-VTCVRFHQDTKNPIVVSASND 491

Query: 292 FNCNVWDSLKCERVGILSGHDNRVSCLGVTADGMAVATGSWDSFLKIWN 340
               VWD+          GH  +++ L ++ + +   +GS D     WN
Sbjct: 492 KTIKVWDNHTMTLKNTFVGHKAQITALDMSTNYL--VSGSKDGIAMTWN 632
>34511
          Length = 1037

 Score = 74.3 bits (181), Expect(2) = 2e-16,   Method: Compositional matrix adjust.
 Identities = 32/40 (80%), Positives = 37/40 (92%)
 Frame = +3

Query: 301 KCERVGILSGHDNRVSCLGVTADGMAVATGSWDSFLKIWN 340
           K ER GIL+GHDNRVSCLGVT +GM+VATGSWDSFL++WN
Sbjct: 39  KAERSGILAGHDNRVSCLGVTENGMSVATGSWDSFLRVWN 158

 Score = 28.5 bits (62), Expect(2) = 2e-16,   Method: Compositional matrix adjust.
 Identities = 10/18 (55%), Positives = 14/18 (77%)
 Frame = +2

Query: 289 YDDFNCNVWDSLKCERVG 306
           YDDFNCNVW +++   +G
Sbjct: 2   YDDFNCNVWYTMESRALG 55
>00561
          Length = 1003

 Score = 71.6 bits (174), Expect(2) = 1e-15,   Method: Compositional matrix adjust.
 Identities = 64/238 (26%), Positives = 99/238 (41%), Gaps = 48/238 (20%)
 Frame = -3

Query: 66  DSKLLVSASQDGKLIVWD-TYTTNKVHAIPLR-----SSWVMTCAYAPSGNFVACGGLDN 119
           D   ++SAS+D  LIVW  T   +  +  P +     S ++     +  GN+   G  D 
Sbjct: 977 DPDTIISASRDKTLIVWKLTRDEDTNYGYPQKRLYGHSHFISDVVLSSDGNYALSGSWDQ 798

Query: 120 MCSIYNLK------------------------------SREGNVKVSRELS--------- 140
              +++L                               SR+  +K+   L+         
Sbjct: 797 TLRLWDLAAGKTTRRFEGHTKDVLSVAFSADNRQIVSGSRDKTIKLWNTLAECKFTIQED 618

Query: 141 AHTGYLSCCRFLDD--NNIVTSSG-DTTCALWDIETGQQKTVFVGHTGDCMSLAVSPDYK 197
            HT ++SC RF  +  N I+ S G D T  +W++   + K    GH G   ++ VSPD  
Sbjct: 617 GHTDWVSCVRFSPNHSNPIIVSCGWDRTVKVWNLANCKLKNNHHGHNGYLNTVTVSPDGS 438

Query: 198 LFISGACDASAKLWDVREGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDL 255
           L  SG  D+ A LWD+ +G    T   H   INA+CF PN   +C      S +++DL
Sbjct: 437 LCTSGGKDSKALLWDLNDGKNLYTLE-HNDIINALCFSPNRYWLCVAY-GPSIKIWDL 270

 Score = 29.3 bits (64), Expect(2) = 1e-15,   Method: Compositional matrix adjust.
 Identities = 12/24 (50%), Positives = 15/24 (62%)
 Frame = -2

Query: 275 SVAFSLSGRLLFAGYDDFNCNVWD 298
           S+A+S  G+ LFAGY D    VW 
Sbjct: 192 SLAWSTDGQTLFAGYSDNTIRVWQ 121

 Score = 68.2 bits (165), Expect = 4e-12,   Method: Compositional matrix adjust.
 Identities = 48/196 (24%), Positives = 91/196 (46%), Gaps = 8/196 (4%)
 Frame = -3

Query: 153 DDNNIVTSSGDTTCALW------DIETGQQKTVFVGHTGDCMSLAVSPDYKLFISGACDA 206
           D + I+++S D T  +W      D   G  +    GH+     + +S D    +SG+ D 
Sbjct: 977 DPDTIISASRDKTLIVWKLTRDEDTNYGYPQKRLYGHSHFISDVVLSSDGNYALSGSWDQ 798

Query: 207 SAKLWDVREGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRADQELTAYSQ 266
           + +LWD+  G   + F GH  D+ ++ F  +   I +GS D + +L++  A+ + T   +
Sbjct: 797 TLRLWDLAAGKTTRRFEGHTKDVLSVAFSADNRQIVSGSRDKTIKLWNTLAECKFTI-QE 621

Query: 267 ESIICGITSVAFSL--SGRLLFAGYDDFNCNVWDSLKCERVGILSGHDNRVSCLGVTADG 324
           +     ++ V FS   S  ++ +   D    VW+   C+      GH+  ++ + V+ DG
Sbjct: 620 DGHTDWVSCVRFSPNHSNPIIVSCGWDRTVKVWNLANCKLKNNHHGHNGYLNTVTVSPDG 441

Query: 325 MAVATGSWDSFLKIWN 340
               +G  DS   +W+
Sbjct: 440 SLCTSGGKDSKALLWD 393

 Score = 55.8 bits (133), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 44/172 (25%), Positives = 78/172 (45%), Gaps = 4/172 (2%)
 Frame = -3

Query: 46  RTRRTLRGHLAKIYAMHWATDSKLLVSASQDGKLIVWDTYTTNKVHAIPL-RSSWVMTCA 104
           +T R   GH   + ++ ++ D++ +VS S+D  + +W+T    K        + WV    
Sbjct: 767 KTTRRFEGHTKDVLSVAFSADNRQIVSGSRDKTIKLWNTLAECKFTIQEDGHTDWVSCVR 588

Query: 105 YAP--SGNFVACGGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFLDDNNIVTSSG 162
           ++P  S   +   G D    ++NL     N K+      H GYL+      D ++ TS G
Sbjct: 587 FSPNHSNPIIVSCGWDRTVKVWNL----ANCKLKNNHHGHNGYLNTVTVSPDGSLCTSGG 420

Query: 163 -DTTCALWDIETGQQKTVFVGHTGDCMSLAVSPDYKLFISGACDASAKLWDV 213
            D+   LWD+  G+     + H     +L  SP+ + ++  A   S K+WD+
Sbjct: 419 KDSKALLWDLNDGKN-LYTLEHNDIINALCFSPN-RYWLCVAYGPSIKIWDL 270

 Score = 55.8 bits (133), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 57/210 (27%), Positives = 93/210 (44%), Gaps = 6/210 (2%)
 Frame = -3

Query: 137 RELSAHTGYLSCCRFLDDNNIVTS-SGDTTCALWDIETGQQKTVFVGHTGDCMSLAVSPD 195
           + L  H+ ++S      D N   S S D T  LWD+  G+    F GHT D +S+A S D
Sbjct: 884 KRLYGHSHFISDVVLSSDGNYALSGSWDQTLRLWDLAAGKTTRRFEGHTKDVLSVAFSAD 705

Query: 196 YKLFISGACDASAKLWDVREGTCRQTFT--GHESDINAICFFPN--GEAICTGSDDASCR 251
            +  +SG+ D + KLW+     C+ T    GH   ++ + F PN     I +   D + +
Sbjct: 704 NRQIVSGSRDKTIKLWNTL-AECKFTIQEDGHTDWVSCVRFSPNHSNPIIVSCGWDRTVK 528

Query: 252 LFDLRADQELTAYSQESIICGITSVAFSLSGRLLFAGYDDFNCNVWDSLKCERVGILSGH 311
           +++L A+ +L   +       + +V  S  G L  +G  D    +WD    + +  L  +
Sbjct: 527 VWNL-ANCKLKN-NHHGHNGYLNTVTVSPDGSLCTSGGKDSKALLWDLNDGKNLYTLEHN 354

Query: 312 D-NRVSCLGVTADGMAVATGSWDSFLKIWN 340
           D     C       + VA G     +KIW+
Sbjct: 353 DIINALCFSPNRYWLCVAYG---PSIKIWD 273
>13335
          Length = 863

 Score = 78.2 bits (191), Expect = 5e-15,   Method: Compositional matrix adjust.
 Identities = 64/235 (27%), Positives = 105/235 (44%), Gaps = 23/235 (9%)
 Frame = +1

Query: 129 REGNVKVSRELSAHTGYLSCCRFLDDNNIVTSSGDTTCALWDIETGQQKTVFVGHTGDCM 188
           + G++K   + ++ +    C      +++V+ S D T  +W++ T +    +VGH    M
Sbjct: 22  KTGSIKGEYQHASKSSIRVCKFSPSSSHLVSGSDDDTICMWEVATQKLVRSYVGHEDSVM 201

Query: 189 SLAVSPDYKLFISGACDASAKLWDVREGTCRQ-TFTGHESDINAIC--FFPNGEAIC--- 242
           +LA SP+    +SG+ +    +WD   G CR  T      D+   C  F P     C   
Sbjct: 202 ALAYSPNGHYLVSGSPNGDLYVWDASFGHCRHLTLRVDAHDLGVTCCEFSPTFGTACAEN 381

Query: 243 ---------TGSDDASCRLFDLRAD---QELTAYSQESIICG----ITSVAFSLSGRLLF 286
                    TG  D   +L+   A     E+T   ++ I+ G    + + AFS S  LL 
Sbjct: 382 SSTCNLLLATGGKDNLIKLWTFSAQVGSPEVTLQCRD-ILSGHSDLVMACAFSPSSALLA 558

Query: 287 AGYDDFNCNVWDSLK-CERVGILSGHDNRVSCLGVTADGMAVATGSWDSFLKIWN 340
           +G  D +  +WDS+K      I + H   V+C   + DG  +A+GS D  +KIW 
Sbjct: 559 SGSFDKSVRLWDSVKGVALFSIEACHSRFVTCCAFSIDGTLLASGSMDRIIKIWK 723

 Score = 58.2 bits (139), Expect = 4e-09,   Method: Compositional matrix adjust.
 Identities = 52/216 (24%), Positives = 89/216 (41%), Gaps = 23/216 (10%)
 Frame = +1

Query: 63  WATDSKLLVSASQDGKLIVWDTYTTNKVHAIPLRSSWVMTCAYAPSGNFVACGGLDNMCS 122
           ++  S  LVS S D  + +W+  T   V +       VM  AY+P+G+++  G  +    
Sbjct: 85  FSPSSSHLVSGSDDDTICMWEVATQKLVRSYVGHEDSVMALAYSPNGHYLVSGSPNG--D 258

Query: 123 IYNLKSREGNVK-VSRELSAHTGYLSCCRFLDDNNIVTSSGDTTC-------------AL 168
           +Y   +  G+ + ++  + AH   ++CC F        +   +TC              L
Sbjct: 259 LYVWDASFGHCRHLTLRVDAHDLGVTCCEFSPTFGTACAENSSTCNLLLATGGKDNLIKL 438

Query: 169 WDIE--------TGQQKTVFVGHTGDCMSLAVSPDYKLFISGACDASAKLWDVREGTCRQ 220
           W           T Q + +  GH+   M+ A SP   L  SG+ D S +LWD  +G    
Sbjct: 439 WTFSAQVGSPEVTLQCRDILSGHSDLVMACAFSPSSALLASGSFDKSVRLWDSVKGVALF 618

Query: 221 TFTGHESDINAICFFP-NGEAICTGSDDASCRLFDL 255
           +     S     C F  +G  + +GS D   +++ L
Sbjct: 619 SIEACHSRFVTCCAFSIDGTLLASGSMDRIIKIWKL 726

 Score = 55.8 bits (133), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 51/197 (25%), Positives = 86/197 (43%), Gaps = 24/197 (12%)
 Frame = +1

Query: 168 LWDIETGQQKTVFVGHTGDCMSL-AVSPDYKLFISGACDASAKLWDVREGTCRQTFTGHE 226
           +WD++TG  K  +   +   + +   SP     +SG+ D +  +W+V      +++ GHE
Sbjct: 10  VWDVKTGSIKGEYQHASKSSIRVCKFSPSSSHLVSGSDDDTICMWEVATQKLVRSYVGHE 189

Query: 227 SDINAICFFPNGEAICTGSD-------DAS---CRLFDLRADQELTAYS--QESIICGIT 274
             + A+ + PNG  + +GS        DAS   CR   LR D      +  + S   G  
Sbjct: 190 DSVMALAYSPNGHYLVSGSPNGDLYVWDASFGHCRHLTLRVDAHDLGVTCCEFSPTFGTA 369

Query: 275 SVAFSLSGRLLFA-GYDDFNCNVWD----------SLKCERVGILSGHDNRVSCLGVTAD 323
               S +  LL A G  D    +W           +L+C    ILSGH + V     +  
Sbjct: 370 CAENSSTCNLLLATGGKDNLIKLWTFSAQVGSPEVTLQCR--DILSGHSDLVMACAFSPS 543

Query: 324 GMAVATGSWDSFLKIWN 340
              +A+GS+D  +++W+
Sbjct: 544 SALLASGSFDKSVRLWD 594

 Score = 50.8 bits (120), Expect = 7e-07,   Method: Compositional matrix adjust.
 Identities = 49/191 (25%), Positives = 84/191 (43%), Gaps = 24/191 (12%)
 Frame = +1

Query: 49  RTLRGHLAKIYAMHWATDSKLLVSASQDGKLIVWDT------YTTNKVHAIPLRSSWVMT 102
           R+  GH   + A+ ++ +   LVS S +G L VWD       + T +V A  L    V  
Sbjct: 169 RSYVGHEDSVMALAYSPNGHYLVSGSPNGDLYVWDASFGHCRHLTLRVDAHDLG---VTC 339

Query: 103 CAYAPSGN------------FVACGGLDNMCSIYNLKSREGNVKVSRE----LSAHTGYL 146
           C ++P+               +A GG DN+  ++   ++ G+ +V+ +    LS H+  +
Sbjct: 340 CEFSPTFGTACAENSSTCNLLLATGGKDNLIKLWTFSAQVGSPEVTLQCRDILSGHSDLV 519

Query: 147 SCCRFLDDNNIVTS-SGDTTCALWDIETGQQK-TVFVGHTGDCMSLAVSPDYKLFISGAC 204
             C F   + ++ S S D +  LWD   G    ++   H+      A S D  L  SG+ 
Sbjct: 520 MACAFSPSSALLASGSFDKSVRLWDSVKGVALFSIEACHSRFVTCCAFSIDGTLLASGSM 699

Query: 205 DASAKLWDVRE 215
           D   K+W + +
Sbjct: 700 DRIIKIWKLTD 732

 Score = 40.0 bits (92), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 25/86 (29%), Positives = 42/86 (48%), Gaps = 1/86 (1%)
 Frame = +1

Query: 42  RVQMRTRRTLRGHLAKIYAMHWATDSKLLVSASQDGKLIVWDTYTTNKVHAIPL-RSSWV 100
            V ++ R  L GH   + A  ++  S LL S S D  + +WD+     + +I    S +V
Sbjct: 469 EVTLQCRDILSGHSDLVMACAFSPSSALLASGSFDKSVRLWDSVKGVALFSIEACHSRFV 648

Query: 101 MTCAYAPSGNFVACGGLDNMCSIYNL 126
             CA++  G  +A G +D +  I+ L
Sbjct: 649 TCCAFSIDGTLLASGSMDRIIKIWKL 726
>30256
          Length = 961

 Score = 76.6 bits (187), Expect = 1e-14,   Method: Compositional matrix adjust.
 Identities = 67/237 (28%), Positives = 107/237 (45%), Gaps = 4/237 (1%)
 Frame = +3

Query: 108 SGNFVACGGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFLDDNNIVTSSGDTTCA 167
           +GN V  G  D    ++N  +       +  L  H+  + C   L    +V+ S D T  
Sbjct: 69  TGNTVISGSTDRSLKVWNADTGV----CTHTLYGHSSTVRCLS-LSGKKVVSGSRDATLR 233

Query: 168 LWDIETGQQKTVFVGHTGDCMSLAVSPDYKLFISGACDASAKLWDVREGTCRQTFTGHES 227
           +WDIE+G    V +GH        V  D K  +SGA D + ++WD    +C  T  GH +
Sbjct: 234 VWDIESGHCLNVLLGHMAAVR--CVQYDGKRVVSGAXDYTVRVWDPDTASCLHTLQGHTN 407

Query: 228 DINAICFFPNGEAICTGSDDASCRLFDLRADQEL-TAYSQESIICGITSVAFSLSGRLLF 286
            + ++ F  +G  + +GS D S R++D+R  + + T    +S+  G+      L   LL 
Sbjct: 408 RVYSLQF--DGVYVVSGSLDTSIRVWDVRCGKLVHTLMGHQSLTSGL-----ELKDNLLV 566

Query: 287 AGYDDFNCNVWDSLKCERVGILSG---HDNRVSCLGVTADGMAVATGSWDSFLKIWN 340
           +G  D    VWD    + +  L G   H + V+CL        V T S D  +K+W+
Sbjct: 567 SGNADSTVKVWDVHTGKCLQTLLGPNKHRSAVTCLQFNKK--FVVTCSDDGTVKLWD 731
>02960
          Length = 1577

 Score = 69.7 bits (169), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 51/157 (32%), Positives = 79/157 (50%), Gaps = 4/157 (2%)
 Frame = +2

Query: 139  LSAHTGYLSCCRFLDDNNIVTSSGDTTCALWDIETGQQKTVFVGHTGDCMSLAVSPDYKL 198
            LS H   +S  R+LD + +VTSS D +  LWD+ T QQ ++  G     + +A SP   +
Sbjct: 947  LSGHAEAVSAVRWLDPHRVVTSSWDHSLRLWDLHTAQQTSLIQGSKA-VLDVAYSPLSHM 1123

Query: 199  FISGACDASAKLWDVR--EG-TCRQTFTGHESDINAICFFPNGEAI-CTGSDDASCRLFD 254
             I+G+ D   +L D R  EG T +  FT H   +  + + P  E +  +GS D   +L+D
Sbjct: 1124 LITGSADRHVRLVDPRCSEGETVKCAFTSHTGWVTGVDWSPTREHLFLSGSYDNVLKLWD 1303

Query: 255  LRADQELTAYSQESIICGITSVAFSLSGRLLFAGYDD 291
             R+ +  T Y        I +V +S+   LL  G D+
Sbjct: 1304 TRSPKA-TLYDMNWHEDRILAVDWSIPELLLSGGVDN 1411

 Score = 43.5 bits (101), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 46/196 (23%), Positives = 81/196 (41%), Gaps = 13/196 (6%)
 Frame = +2

Query: 158 VTSSGDTTCALWDIETGQQKTVFVGHTGDCMSLA-----VSPDYKLFISGACDASAKLW- 211
           ++ S D T  LW  + G+      GHT     +A      S     F++G+ D +A +W 
Sbjct: 527 LSGSYDNTVRLWSTK-GEAIMTIPGHTSPVKCVAWIKHDESSGVSTFVTGSHDQTALVWQ 703

Query: 212 ---DVREGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLF--DLRADQELTAYSQ 266
              +  E  CR +  GH + ++ +   P+ + +CTGS D   +L+  D   D + +  ++
Sbjct: 704 WQRETNEVDCRLSCRGHAASVDCVAVSPDSQQMCTGSWDKMLKLWSTDCNVDGDQSEDTE 883

Query: 267 ESIICGITSVAFSLSGRLLFAGYDDFNCNVWDSLKCERVGIL--SGHDNRVSCLGVTADG 324
                  ++ + + +                      RV +L  SGH   VS +    D 
Sbjct: 884 RPSKKKKSAKSTTQT----------------------RVPVLTLSGHAEAVSAVRW-LDP 994

Query: 325 MAVATGSWDSFLKIWN 340
             V T SWD  L++W+
Sbjct: 995 HRVVTSSWDHSLRLWD 1042
>27465
          Length = 658

 Score = 69.7 bits (169), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 40/123 (32%), Positives = 62/123 (50%), Gaps = 2/123 (1%)
 Frame = -1

Query: 139 LSAHTGYLSCCRFLDD-NNIVTSSGDTTCALWDIETGQQKTVFVGHTGDCMSLAVS-PDY 196
           L AH   L+   F    ++ +T S D TC +WD  + ++     GH     ++A + P  
Sbjct: 373 LRAHILPLTNVAFNKSGSSFITGSYDRTCKIWDTASAEELHTLEGHRNVVYAIAFNNPFG 194

Query: 197 KLFISGACDASAKLWDVREGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLR 256
              I+G+ D + KLW   +G C  T  GH ++I  + F P+   I TGS D +CRL+D+ 
Sbjct: 193 DKVITGSFDKTCKLWSTADGKCYHTLRGHTAEIVCVSFNPSSTLIATGSMDTTCRLWDVE 14

Query: 257 ADQ 259
             Q
Sbjct: 13  KAQ 5

 Score = 57.8 bits (138), Expect = 6e-09,   Method: Compositional matrix adjust.
 Identities = 40/130 (30%), Positives = 63/130 (48%), Gaps = 4/130 (3%)
 Frame = -1

Query: 179 VFVGHTGDCMSLAVSPDYKLFISGACDASAKLWDVREGTCRQTFTGHESDINAICF-FPN 237
           V   H     ++A +     FI+G+ D + K+WD        T  GH + + AI F  P 
Sbjct: 376 VLRAHILPLTNVAFNKSGSSFITGSYDRTCKIWDTASAEELHTLEGHRNVVYAIAFNNPF 197

Query: 238 GEAICTGSDDASCRLF---DLRADQELTAYSQESIICGITSVAFSLSGRLLFAGYDDFNC 294
           G+ + TGS D +C+L+   D +    L  ++ E I+C    V+F+ S  L+  G  D  C
Sbjct: 196 GDKVITGSFDKTCKLWSTADGKCYHTLRGHTAE-IVC----VSFNPSSTLIATGSMDTTC 32

Query: 295 NVWDSLKCER 304
            +WD  K +R
Sbjct: 31  RLWDVEKAQR 2

 Score = 56.6 bits (135), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 34/130 (26%), Positives = 59/130 (45%), Gaps = 2/130 (1%)
 Frame = -1

Query: 49  RTLRGHLAKIYAMHWATDSKLLVSASQDGKLIVWDTYTTNKVHAIPLRSSWVMTCAYA-P 107
           + LR H+  +  + +       ++ S D    +WDT +  ++H +    + V   A+  P
Sbjct: 379 KVLRAHILPLTNVAFNKSGSSFITGSYDRTCKIWDTASAEELHTLEGHRNVVYAIAFNNP 200

Query: 108 SGNFVACGGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFLDDNNIV-TSSGDTTC 166
            G+ V  G  D  C +++      + K    L  HT  + C  F   + ++ T S DTTC
Sbjct: 199 FGDKVITGSFDKTCKLWST----ADGKCYHTLRGHTAEIVCVSFNPSSTLIATGSMDTTC 32

Query: 167 ALWDIETGQQ 176
            LWD+E  Q+
Sbjct: 31  RLWDVEKAQR 2

 Score = 48.1 bits (113), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 26/72 (36%), Positives = 36/72 (50%), Gaps = 1/72 (1%)
 Frame = -1

Query: 270 ICGITSVAFSLSGRLLFAGYDDFNCNVWDSLKCERVGILSGHDNRVSCLGVTAD-GMAVA 328
           I  +T+VAF+ SG     G  D  C +WD+   E +  L GH N V  +      G  V 
Sbjct: 361 ILPLTNVAFNKSGSSFITGSYDRTCKIWDTASAEELHTLEGHRNVVYAIAFNNPFGDKVI 182

Query: 329 TGSWDSFLKIWN 340
           TGS+D   K+W+
Sbjct: 181 TGSFDKTCKLWS 146

 Score = 47.8 bits (112), Expect = 6e-06,   Method: Compositional matrix adjust.
 Identities = 29/122 (23%), Positives = 57/122 (46%), Gaps = 1/122 (0%)
 Frame = -1

Query: 220 QTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRADQELTAYSQESIICGITSVAFS 279
           +    H   +  + F  +G +  TGS D +C+++D  + +EL  ++ E     + ++AF+
Sbjct: 379 KVLRAHILPLTNVAFNKSGSSFITGSYDRTCKIWDTASAEEL--HTLEGHRNVVYAIAFN 206

Query: 280 LS-GRLLFAGYDDFNCNVWDSLKCERVGILSGHDNRVSCLGVTADGMAVATGSWDSFLKI 338
              G  +  G  D  C +W +   +    L GH   + C+        +ATGS D+  ++
Sbjct: 205 NPFGDKVITGSFDKTCKLWSTADGKCYHTLRGHTAEIVCVSFNPSSTLIATGSMDTTCRL 26

Query: 339 WN 340
           W+
Sbjct: 25  WD 20
>02147
          Length = 1547

 Score = 68.6 bits (166), Expect = 3e-12,   Method: Compositional matrix adjust.
 Identities = 54/221 (24%), Positives = 88/221 (39%), Gaps = 38/221 (17%)
 Frame = +2

Query: 158 VTSSGDTTCALWDIETGQQKTVFVGHTGDCMSLAVSPDYKLFISGACDASAKLWD-VREG 216
            T + D +  +WD E G++   F  H     S+  S D    ++G+ +   K++D V   
Sbjct: 221 ATGAADFSAKIWDAEKGEELQTF-SHKHIVKSVDFSHDGTALLTGSNEKLLKVFDLVNTD 397

Query: 217 TCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRADQELT-------------- 262
              ++F GH S+I    F  +G+ I + SDD + RL+ L   QE+               
Sbjct: 398 AEPKSFAGHTSNIKGALFLSDGKRIISASDDKTVRLWSLETCQEVQQLTFDTPPTSLTLS 577

Query: 263 --------------AYSQESII---------CGITSVAFSLSGRLLFAGYDDFNCNVWDS 299
                         A+ Q   +           I+S +   S R   AG +DF    +D 
Sbjct: 578 PDKNTIIVTHSQNIAFYQADTLREMKKFEAEAPISSASLHQSERFFVAGGEDFKMYKFDY 757

Query: 300 LKCERVGILSGHDNRVSCLGVTADGMAVATGSWDSFLKIWN 340
              + +    GH   V C+  + DG   A+GS D  L++W 
Sbjct: 758 ETGKEIESFKGHFGPVHCVRFSPDGELYASGSEDGTLRLWQ 880

 Score = 60.1 bits (144), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 42/153 (27%), Positives = 73/153 (47%), Gaps = 1/153 (0%)
 Frame = +2

Query: 172 ETGQQKTVFVGHTGDCMSLAVSPDYKLFISGACDASAKLWDVREGTCRQTFTGHESDINA 231
           +TG     F GH G      ++ +     +GA D SAK+WD  +G   QTF+ H+  + +
Sbjct: 137 DTGDWIGTFEGHKGAVWGATLNREATRAATGAADFSAKIWDAEKGEELQTFS-HKHIVKS 313

Query: 232 ICFFPNGEAICTGSDDASCRLFDL-RADQELTAYSQESIICGITSVAFSLSGRLLFAGYD 290
           + F  +G A+ TGS++   ++FDL   D E  +++  +    I    F   G+ + +  D
Sbjct: 314 VDFSHDGTALLTGSNEKLLKVFDLVNTDAEPKSFAGHT--SNIKGALFLSDGKRIISASD 487

Query: 291 DFNCNVWDSLKCERVGILSGHDNRVSCLGVTAD 323
           D    +W    C+ V  L+  D   + L ++ D
Sbjct: 488 DKTVRLWSLETCQEVQQLT-FDTPPTSLTLSPD 583

 Score = 52.0 bits (123), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 38/168 (22%), Positives = 69/168 (41%)
 Frame = +2

Query: 49  RTLRGHLAKIYAMHWATDSKLLVSASQDGKLIVWDTYTTNKVHAIPLRSSWVMTCAYAPS 108
           ++  GH + I    + +D K ++SAS D  + +W   T  +V  +   +    +   +P 
Sbjct: 407 KSFAGHTSNIKGALFLSDGKRIISASDDKTVRLWSLETCQEVQQLTFDTP-PTSLTLSPD 583

Query: 109 GNFVACGGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFLDDNNIVTSSGDTTCAL 168
            N +      N+   Y   +    ++  ++  A     S      +   V    D     
Sbjct: 584 KNTIIVTHSQNIA-FYQADT----LREMKKFEAEAPISSASLHQSERFFVAGGEDFKMYK 748

Query: 169 WDIETGQQKTVFVGHTGDCMSLAVSPDYKLFISGACDASAKLWDVREG 216
           +D ETG++   F GH G    +  SPD +L+ SG+ D + +LW    G
Sbjct: 749 FDYETGKEIESFKGHFGPVHCVRFSPDGELYASGSEDGTLRLWQTTIG 892

 Score = 42.0 bits (97), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 29/121 (23%), Positives = 54/121 (44%), Gaps = 1/121 (0%)
 Frame = +2

Query: 221 TFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRADQELTAYSQESIICGITSVAFSL 280
           TF GH+  +             TG+ D S +++D    +EL  +S + I+    SV FS 
Sbjct: 158 TFEGHKGAVWGATLNREATRAATGAADFSAKIWDAEKGEELQTFSHKHIV---KSVDFSH 328

Query: 281 SGRLLFAGYDDFNCNVWDSLKCE-RVGILSGHDNRVSCLGVTADGMAVATGSWDSFLKIW 339
            G  L  G ++    V+D +  +      +GH + +      +DG  + + S D  +++W
Sbjct: 329 DGTALLTGSNEKLLKVFDLVNTDAEPKSFAGHTSNIKGALFLSDGKRIISASDDKTVRLW 508

Query: 340 N 340
           +
Sbjct: 509 S 511
>19949
          Length = 903

 Score = 63.5 bits (153), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 41/149 (27%), Positives = 68/149 (45%), Gaps = 1/149 (0%)
 Frame = +2

Query: 100 VMTCAYAPSGNFVACGGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFLDDNN-IV 158
           V +  + P G + A G +D    +++++ R+G +   +    HTG + C RF  D   I 
Sbjct: 2   VKSLDFHPYGAYTASGSMDCNVKLWDIR-RKGCIYTYK---GHTGCVCCLRFSPDGRWIA 169

Query: 159 TSSGDTTCALWDIETGQQKTVFVGHTGDCMSLAVSPDYKLFISGACDASAKLWDVREGTC 218
           ++S D    LWD+  G+  T    H     ++   P   L  SG+ D + K WD+     
Sbjct: 170 SASEDGLVKLWDLTAGKLLTDLKLHRDAVNTIEFHPHEFLLASGSADRTVKFWDLETFQL 349

Query: 219 RQTFTGHESDINAICFFPNGEAICTGSDD 247
             T     + I +I F P+G  + +GS D
Sbjct: 350 ISTTEPEANSIRSILFHPDGVCLYSGSKD 436

 Score = 62.0 bits (149), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 44/146 (30%), Positives = 64/146 (43%), Gaps = 3/146 (2%)
 Frame = +2

Query: 159 TSSGDTTC--ALWDIETGQQKTVFVGHTGDCMSLAVSPDYKLFISGACDASAKLWDVREG 216
           T+SG   C   LWDI        + GHTG    L  SPD +   S + D   KLWD+  G
Sbjct: 38  TASGSMDCNVKLWDIRRKGCIYTYKGHTGCVCCLRFSPDGRWIASASEDGLVKLWDLTAG 217

Query: 217 TCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRADQELTAYSQESIICGITSV 276
                   H   +N I F P+   + +GS D + + +DL   Q ++    E+    I S+
Sbjct: 218 KLLTDLKLHRDAVNTIEFHPHEFLLASGSADRTVKFWDLETFQLISTTEPEA--NSIRSI 391

Query: 277 AFSLSGRLLFAGYDD-FNCNVWDSLK 301
            F   G  L++G  D      W+ L+
Sbjct: 392 LFHPDGVCLYSGSKDTLKVYHWEPLE 469

 Score = 60.5 bits (145), Expect = 9e-10,   Method: Compositional matrix adjust.
 Identities = 42/152 (27%), Positives = 69/152 (45%)
 Frame = +2

Query: 189 SLAVSPDYKLFISGACDASAKLWDVREGTCRQTFTGHESDINAICFFPNGEAICTGSDDA 248
           SL   P      SG+ D + KLWD+R   C  T+ GH   +  + F P+G  I + S+D 
Sbjct: 8   SLDFHPYGAYTASGSMDCNVKLWDIRRKGCIYTYKGHTGCVCCLRFSPDGRWIASASEDG 187

Query: 249 SCRLFDLRADQELTAYSQESIICGITSVAFSLSGRLLFAGYDDFNCNVWDSLKCERVGIL 308
             +L+DL A + LT          + ++ F     LL +G  D     WD    + +   
Sbjct: 188 LVKLWDLTAGKLLTDLKLHRD--AVNTIEFHPHEFLLASGSADRTVKFWDLETFQLISTT 361

Query: 309 SGHDNRVSCLGVTADGMAVATGSWDSFLKIWN 340
               N +  +    DG+ + +GS D+ LK+++
Sbjct: 362 EPEANSIRSILFHPDGVCLYSGSKDT-LKVYH 454

 Score = 35.8 bits (81), Expect = 0.023,   Method: Compositional matrix adjust.
 Identities = 20/68 (29%), Positives = 32/68 (47%)
 Frame = +2

Query: 273 ITSVAFSLSGRLLFAGYDDFNCNVWDSLKCERVGILSGHDNRVSCLGVTADGMAVATGSW 332
           + S+ F   G    +G  D N  +WD  +   +    GH   V CL  + DG  +A+ S 
Sbjct: 2   VKSLDFHPYGAYTASGSMDCNVKLWDIRRKGCIYTYKGHTGCVCCLRFSPDGRWIASASE 181

Query: 333 DSFLKIWN 340
           D  +K+W+
Sbjct: 182 DGLVKLWD 205

 Score = 35.8 bits (81), Expect = 0.025,   Method: Compositional matrix adjust.
 Identities = 30/135 (22%), Positives = 54/135 (40%), Gaps = 1/135 (0%)
 Frame = +2

Query: 72  SASQDGKLIVWDTYTTNKVHAIPLRSSWVMTCAYAPSGNFVACGGLDNMCSIYNLKSREG 131
           S S D  + +WD      ++     +  V    ++P G ++A    D +  +++L +   
Sbjct: 44  SGSMDCNVKLWDIRRKGCIYTYKGHTGCVCCLRFSPDGRWIASASEDGLVKLWDLTAG-- 217

Query: 132 NVKVSRELSAHTGYLSCCRFLDDNNIVTS-SGDTTCALWDIETGQQKTVFVGHTGDCMSL 190
             K+  +L  H   ++   F     ++ S S D T   WD+ET Q  +          S+
Sbjct: 218 --KLLTDLKLHRDAVNTIEFHPHEFLLASGSADRTVKFWDLETFQLISTTEPEANSIRSI 391

Query: 191 AVSPDYKLFISGACD 205
              PD     SG+ D
Sbjct: 392 LFHPDGVCLYSGSKD 436

 Score = 35.8 bits (81), Expect = 0.029,   Method: Compositional matrix adjust.
 Identities = 19/79 (24%), Positives = 37/79 (46%)
 Frame = +2

Query: 50  TLRGHLAKIYAMHWATDSKLLVSASQDGKLIVWDTYTTNKVHAIPLRSSWVMTCAYAPSG 109
           T +GH   +  + ++ D + + SAS+DG + +WD      +  + L    V T  + P  
Sbjct: 104 TYKGHTGCVCCLRFSPDGRWIASASEDGLVKLWDLTAGKLLTDLKLHRDAVNTIEFHPHE 283

Query: 110 NFVACGGLDNMCSIYNLKS 128
             +A G  D     ++L++
Sbjct: 284 FLLASGSADRTVKFWDLET 340
>17602
          Length = 481

 Score = 63.2 bits (152), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 40/136 (29%), Positives = 65/136 (47%), Gaps = 4/136 (2%)
 Frame = +3

Query: 209 KLWDVREGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRADQELTAYSQES 268
           ++WDV+ G C +T   H   + A+ F  +G  I + S D  CR++D  + Q L     + 
Sbjct: 3   RIWDVKTGKCLKTLPAHSDPVTAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLXTLIDDD 182

Query: 269 IICGITSVAFSLSGRLLFAGYDDFNCNVWDSLKCERVGILSGHDNRVSCL----GVTADG 324
               ++ V FS +G+ + A   D    +WD  K + +    GH N   C+     VT  G
Sbjct: 183 NP-PVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYVGHRNEKYCIFANFSVTG-G 356

Query: 325 MAVATGSWDSFLKIWN 340
             + +GS D+ + IWN
Sbjct: 357 KWIVSGSEDNMVYIWN 404

 Score = 49.3 bits (116), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 31/135 (22%), Positives = 62/135 (45%), Gaps = 2/135 (1%)
 Frame = +3

Query: 168 LWDIETGQQKTVFVGHTGDCMSLAVSPDYKLFISGACDASAKLWDVREGTCRQTFTGHES 227
           +WD++TG+       H+    ++  + D  L +S + D   ++WD   G C  T    ++
Sbjct: 6   IWDVKTGKCLKTLPAHSDPVTAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLXTLIDDDN 185

Query: 228 -DINAICFFPNGEAICTGSDDASCRLFDLRADQELTAYSQESIICGITSVAFSLS-GRLL 285
             ++ + F PNG+ I   + D + +L+D    + L  Y             FS++ G+ +
Sbjct: 186 PPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYVGHRNEKYCIFANFSVTGGKWI 365

Query: 286 FAGYDDFNCNVWDSL 300
            +G +D    +W+ L
Sbjct: 366 VSGSEDNMVYIWNLL 410

 Score = 38.9 bits (89), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 22/78 (28%), Positives = 40/78 (51%), Gaps = 1/78 (1%)
 Frame = +3

Query: 49  RTLRGHLAKIYAMHWATDSKLLVSASQDGKLIVWDTYTTNKVHA-IPLRSSWVMTCAYAP 107
           +TL  H   + A+H+  D  L+VS+S DG   +WDT +   +   I   +  V    ++P
Sbjct: 36  KTLPAHSDPVTAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLXTLIDDDNPPVSFVKFSP 215

Query: 108 SGNFVACGGLDNMCSIYN 125
           +G ++    LDN   +++
Sbjct: 216 NGKYILAATLDNTLKLWD 269

 Score = 35.0 bits (79), Expect = 0.041,   Method: Compositional matrix adjust.
 Identities = 30/139 (21%), Positives = 58/139 (41%), Gaps = 4/139 (2%)
 Frame = +3

Query: 81  VWDTYTTNKVHAIPLRSSWVMTCAYAPSGNFVACGGLDNMCSIYNLKSREGNVKVSRELS 140
           +WD  T   +  +P  S  V    +   G+ +     D +C I++  S +    +   + 
Sbjct: 6   IWDVKTGKCLKTLPAHSDPVTAVHFNRDGSLIVSSSYDGLCRIWDTASGQC---LXTLID 176

Query: 141 AHTGYLSCCRFLDDNN-IVTSSGDTTCALWDIETGQQKTVFVGHTGD--CMSLAVS-PDY 196
                +S  +F  +   I+ ++ D T  LWD   G+    +VGH  +  C+    S    
Sbjct: 177 DDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYVGHRNEKYCIFANFSVTGG 356

Query: 197 KLFISGACDASAKLWDVRE 215
           K  +SG+ D    +W++ +
Sbjct: 357 KWIVSGSEDNMVYIWNLLD 413
>02090
          Length = 1841

 Score = 60.5 bits (145), Expect = 9e-10,   Method: Compositional matrix adjust.
 Identities = 48/178 (26%), Positives = 77/178 (43%), Gaps = 2/178 (1%)
 Frame = -3

Query: 164  TTCALWDI--ETGQQKTVFVGHTGDCMSLAVSPDYKLFISGACDASAKLWDVREGTCRQT 221
            +T ++WD+   T + K         C +LA+SPD K+  S   D +  +WD+   T  + 
Sbjct: 1692 STLSIWDLATPTPRIKAELTSSAPACYALAISPDGKVCFSCCSDGNIAVWDLHNQTLVRQ 1513

Query: 222  FTGHESDINAICFFPNGEAICTGSDDASCRLFDLRADQELTAYSQESIICGITSVAFSLS 281
            F GH    + I   P+G  + TG  D + R +DLR  ++L    Q      I S+ +  +
Sbjct: 1512 FQGHTDGASCIDISPDGTKLWTGGLDNTVRSWDLREGRQL---QQHDFSSQIFSLGYCPT 1342

Query: 282  GRLLFAGYDDFNCNVWDSLKCERVGILSGHDNRVSCLGVTADGMAVATGSWDSFLKIW 339
            G  L  G +  N  V    K ++   L  H++ V  L     G    +   D+ L  W
Sbjct: 1341 GEWLAVGMESSNVEVLHHSKPDKYQ-LHLHESCVLSLKFAYCGKWFVSTGKDNLLNAW 1171

 Score = 51.6 bits (122), Expect = 5e-07,   Method: Compositional matrix adjust.
 Identities = 53/223 (23%), Positives = 86/223 (38%), Gaps = 11/223 (4%)
 Frame = -3

Query: 122  SIYNLKSREGNVKVSRELSAHTGY-----------LSCCRFLDDNNIVTSSGDTTCALWD 170
            SI++L +    +K     SA   Y            SCC    D NI         A+WD
Sbjct: 1683 SIWDLATPTPRIKAELTSSAPACYALAISPDGKVCFSCCS---DGNI---------AVWD 1540

Query: 171  IETGQQKTVFVGHTGDCMSLAVSPDYKLFISGACDASAKLWDVREGTCRQTFTGHESDIN 230
            +        F GHT     + +SPD     +G  D + + WD+REG   Q      S I 
Sbjct: 1539 LHNQTLVRQFQGHTDGASCIDISPDGTKLWTGGLDNTVRSWDLREGRQLQQHD-FSSQIF 1363

Query: 231  AICFFPNGEAICTGSDDASCRLFDLRADQELTAYSQESIICGITSVAFSLSGRLLFAGYD 290
            ++ + P GE +  G + ++  +       +   +  ES    + S+ F+  G+   +   
Sbjct: 1362 SLGYCPTGEWLAVGMESSNVEVLHHSKPDKYQLHLHESC---VLSLKFAYCGKWFVSTGK 1192

Query: 291  DFNCNVWDSLKCERVGILSGHDNRVSCLGVTADGMAVATGSWD 333
            D   N W +     +       + +SC  + AD   + TGS D
Sbjct: 1191 DNLLNAWRTPYGASIFQSKESSSVLSC-DIAADDKYIVTGSGD 1066

 Score = 38.5 bits (88), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 20/66 (30%), Positives = 34/66 (51%)
 Frame = -3

Query: 275  SVAFSLSGRLLFAGYDDFNCNVWDSLKCERVGILSGHDNRVSCLGVTADGMAVATGSWDS 334
            ++A S  G++ F+   D N  VWD      V    GH +  SC+ ++ DG  + TG  D+
Sbjct: 1611 ALAISPDGKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISPDGTKLWTGGLDN 1432

Query: 335  FLKIWN 340
             ++ W+
Sbjct: 1431 TVRSWD 1414

 Score = 37.7 bits (86), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 27/104 (25%), Positives = 40/104 (38%)
 Frame = -3

Query: 46   RTRRTLRGHLAKIYAMHWATDSKLLVSASQDGKLIVWDTYTTNKVHAIPLRSSWVMTCAY 105
            R +  L       YA+  + D K+  S   DG + VWD +    V      +        
Sbjct: 1653 RIKAELTSSAPACYALAISPDGKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGASCIDI 1474

Query: 106  APSGNFVACGGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCC 149
            +P G  +  GGLDN    ++L  REG      + S+    L  C
Sbjct: 1473 SPDGTKLWTGGLDNTVRSWDL--REGRQLQQHDFSSQIFSLGYC 1348

 Score = 32.3 bits (72), Expect = 0.27,   Method: Compositional matrix adjust.
 Identities = 31/129 (24%), Positives = 59/129 (45%), Gaps = 2/129 (1%)
 Frame = -3

Query: 45   MRTRRTLRGH--LAKIYAMHWATDSKLLVSASQDGKLIVWDTYTTNKVHAIPLRSSWVMT 102
            +R  R L+ H   ++I+++ +    + L    +   + V      +K + + L  S V++
Sbjct: 1413 LREGRQLQQHDFSSQIFSLGYCPTGEWLAVGMESSNVEVLHHSKPDK-YQLHLHESCVLS 1237

Query: 103  CAYAPSGNFVACGGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFLDDNNIVTSSG 162
              +A  G +    G DN+ + +       ++  S+E S+    LSC    DD  IVT SG
Sbjct: 1236 LKFAYCGKWFVSTGKDNLLNAWR-TPYGASIFQSKESSS---VLSCDIAADDKYIVTGSG 1069

Query: 163  DTTCALWDI 171
            D    L+++
Sbjct: 1068 DKKATLYEV 1042
>21105
          Length = 650

 Score = 55.1 bits (131), Expect = 4e-08,   Method: Compositional matrix adjust.
 Identities = 30/100 (30%), Positives = 46/100 (46%), Gaps = 4/100 (4%)
 Frame = +1

Query: 158 VTSSGDTTCALWDIETGQQKTVFVGHTGDCMSLAVSPDYKLFISGACDASAKLWDVREGT 217
           +T+  D     +D  TG+     V H     SLAV P+    +SG+ D S +LW++   T
Sbjct: 112 ITAHEDRHIRFFDNNTGKLIHAMVAHLDSVTSLAVDPNGLYLLSGSHDCSIRLWNLDSKT 291

Query: 218 CRQTFTGH----ESDINAICFFPNGEAICTGSDDASCRLF 253
           C Q  T H    +  I+ + F P    I +   DA  ++F
Sbjct: 292 CVQEITSHRKKFDESIHDVAFHPQKPYIASAGADALAKVF 411

 Score = 29.3 bits (64), Expect = 2.3,   Method: Compositional matrix adjust.
 Identities = 16/68 (23%), Positives = 31/68 (45%)
 Frame = +1

Query: 62  HWATDSKLLVSASQDGKLIVWDTYTTNKVHAIPLRSSWVMTCAYAPSGNFVACGGLDNMC 121
           H      + ++A +D  +  +D  T   +HA+      V + A  P+G ++  G  D   
Sbjct: 85  HQHPTMPITITAHEDRHIRFFDNNTGKLIHAMVAHLDSVTSLAVDPNGLYLLSGSHDCSI 264

Query: 122 SIYNLKSR 129
            ++NL S+
Sbjct: 265 RLWNLDSK 288
>03156
          Length = 1014

 Score = 54.7 bits (130), Expect = 5e-08,   Method: Compositional matrix adjust.
 Identities = 44/190 (23%), Positives = 81/190 (42%), Gaps = 14/190 (7%)
 Frame = +1

Query: 49  RTLRGHLAKIYAMHWATDSKLLVSASQDGKLIVWDTYTTNKVHAIPLRSSWVMTCAYAPS 108
           R   GH   + A+H  TD+ LL S S+D  + +WD  T   +    +  + V    + P 
Sbjct: 163 RDFIGHDMVVTAIHLNTDNTLLCSGSRDNTVRIWDVETGACLRQNNIPQNLVTDVKWLPG 342

Query: 109 GNFVACGGLDNMCSIYNLK--------SREGNVKVSRELSAHTGY-LSCCRFLDDNNIVT 159
            + +   G D    IY+ +        +++  +++S +++A   + L+C      N    
Sbjct: 343 SHLIIQAGEDKEVRIYDSRTLGIVRSFTKKQYIQMSCDVTADGQFCLTCSNGFGGNGCEA 522

Query: 160 SSGDTTCALWDIETGQQKTVFVGH---TGDCMSLAVSPDYKLFISGACDASAKLWDV--R 214
           +       LW +  G  +  F GH      C+ L  + D  L  + + D S ++W++  +
Sbjct: 523 T-------LWQLSDGSIQNEFKGHREAIEACLFLPSNQDMTLIATASRDCSVRVWNMFTK 681

Query: 215 EGTCRQTFTG 224
           E  C Q F G
Sbjct: 682 ECVCEQNFEG 711

 Score = 53.9 bits (128), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 43/193 (22%), Positives = 84/193 (43%), Gaps = 7/193 (3%)
 Frame = +1

Query: 155 NNIVTSSGDTTCALWDIETGQQKTVFVGHTGDCMSLAVSPDYKLFISGACDASAKLWDVR 214
           N + ++S D T  +W          F+GH     ++ ++ D  L  SG+ D + ++WDV 
Sbjct: 94  NGMFSASRDKTIKMWQRGNSHSIRDFIGHDMVVTAIHLNTDNTLLCSGSRDNTVRIWDVE 273

Query: 215 EGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRADQELTAYSQESII---C 271
            G C +     ++ +  + + P    I    +D   R++D R    + +++++  I   C
Sbjct: 274 TGACLRQNNIPQNLVTDVKWLPGSHLIIQAGEDKEVRIYDSRTLGIVRSFTKKQYIQMSC 453

Query: 272 GITSVA-FSLSGRLLFAGYDDFNCNVWDSLKCERVGILSGHDNRV-SCLGVTA--DGMAV 327
            +T+   F L+    F G +     +W            GH   + +CL + +  D   +
Sbjct: 454 DVTADGQFCLTCSNGFGG-NGCEATLWQLSDGSIQNEFKGHREAIEACLFLPSNQDMTLI 630

Query: 328 ATGSWDSFLKIWN 340
           AT S D  +++WN
Sbjct: 631 ATASRDCSVRVWN 669

 Score = 35.4 bits (80), Expect = 0.034,   Method: Compositional matrix adjust.
 Identities = 34/157 (21%), Positives = 65/157 (41%), Gaps = 4/157 (2%)
 Frame = +1

Query: 172 ETGQQKTVFVGHTGDCMSLAVSPDYKLFISGACDASAKLWDVREGTCRQTFTGHESDINA 231
           + G+ +  + GH  +   +          S + D + K+W        + F GH+  + A
Sbjct: 19  KMGRLEDRWTGHDREITKVCYGASCNGMFSASRDKTIKMWQRGNSHSIRDFIGHDMVVTA 198

Query: 232 ICFFPNGEAICTGSDDASCRLFDLRADQELTAYSQESIICGITSVAFSLSGRLLFAGYDD 291
           I    +   +C+GS D + R++D+     L   +    +  +T V +     L+    +D
Sbjct: 199 IHLNTDNTLLCSGSRDNTVRIWDVETGACLRQNNIPQNL--VTDVKWLPGSHLIIQAGED 372

Query: 292 FNCNVWDSLKCERVGILSGHDNR----VSCLGVTADG 324
               ++DS     +GI+     +    +SC  VTADG
Sbjct: 373 KEVRIYDS---RTLGIVRSFTKKQYIQMSC-DVTADG 471

 Score = 32.3 bits (72), Expect = 0.29,   Method: Compositional matrix adjust.
 Identities = 20/85 (23%), Positives = 37/85 (43%)
 Frame = +1

Query: 256 RADQELTAYSQESIICGITSVAFSLSGRLLFAGYDDFNCNVWDSLKCERVGILSGHDNRV 315
           R +   T + +E     IT V +  S   +F+   D    +W       +    GHD  V
Sbjct: 28  RLEDRWTGHDRE-----ITKVCYGASCNGMFSASRDKTIKMWQRGNSHSIRDFIGHDMVV 192

Query: 316 SCLGVTADGMAVATGSWDSFLKIWN 340
           + + +  D   + +GS D+ ++IW+
Sbjct: 193 TAIHLNTDNTLLCSGSRDNTVRIWD 267
>01327
          Length = 2215

 Score = 54.7 bits (130), Expect = 5e-08,   Method: Compositional matrix adjust.
 Identities = 44/190 (23%), Positives = 81/190 (42%), Gaps = 14/190 (7%)
 Frame = +3

Query: 49  RTLRGHLAKIYAMHWATDSKLLVSASQDGKLIVWDTYTTNKVHAIPLRSSWVMTCAYAPS 108
           R   GH   + A+H  TD+ LL S S+D  + +WD  T   +    +  + V    + P 
Sbjct: 273 RDFIGHDMVVTAIHLNTDNTLLCSGSRDNTVRIWDVETGACLRQNNIPQNLVTDVKWLPG 452

Query: 109 GNFVACGGLDNMCSIYNLK--------SREGNVKVSRELSAHTGY-LSCCRFLDDNNIVT 159
            + +   G D    IY+ +        +++  +++S +++A   + L+C      N    
Sbjct: 453 SHLIIQAGEDKEVRIYDSRTLGIVRSFTKKQYIQMSCDVTADGQFCLTCSNGFGGNGCEA 632

Query: 160 SSGDTTCALWDIETGQQKTVFVGH---TGDCMSLAVSPDYKLFISGACDASAKLWDV--R 214
           +       LW +  G  +  F GH      C+ L  + D  L  + + D S ++W++  +
Sbjct: 633 T-------LWQLSDGSIQNEFKGHREAIEACLFLPSNQDMTLIATASRDCSVRVWNMFTK 791

Query: 215 EGTCRQTFTG 224
           E  C Q F G
Sbjct: 792 ECVCEQNFEG 821

 Score = 53.5 bits (127), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 43/193 (22%), Positives = 84/193 (43%), Gaps = 7/193 (3%)
 Frame = +3

Query: 155 NNIVTSSGDTTCALWDIETGQQKTVFVGHTGDCMSLAVSPDYKLFISGACDASAKLWDVR 214
           N + ++S D T  +W          F+GH     ++ ++ D  L  SG+ D + ++WDV 
Sbjct: 204 NGMFSASRDKTIKMWQRGNSHSIRDFIGHDMVVTAIHLNTDNTLLCSGSRDNTVRIWDVE 383

Query: 215 EGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRADQELTAYSQESII---C 271
            G C +     ++ +  + + P    I    +D   R++D R    + +++++  I   C
Sbjct: 384 TGACLRQNNIPQNLVTDVKWLPGSHLIIQAGEDKEVRIYDSRTLGIVRSFTKKQYIQMSC 563

Query: 272 GITSVA-FSLSGRLLFAGYDDFNCNVWDSLKCERVGILSGHDNRV-SCLGVTA--DGMAV 327
            +T+   F L+    F G +     +W            GH   + +CL + +  D   +
Sbjct: 564 DVTADGQFCLTCSNGFGG-NGCEATLWQLSDGSIQNEFKGHREAIEACLFLPSNQDMTLI 740

Query: 328 ATGSWDSFLKIWN 340
           AT S D  +++WN
Sbjct: 741 ATASRDCSVRVWN 779

 Score = 43.5 bits (101), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 38/171 (22%), Positives = 73/171 (42%), Gaps = 4/171 (2%)
 Frame = +3

Query: 158 VTSSGDTTCALWDIETGQQKTVFVGHTGDCMSLAVSPDYKLFISGACDASAKLWDVREGT 217
           ++ S D +  L+D + G+ +  + GH  +   +          S + D + K+W      
Sbjct: 87  LSGSKDKSVVLYDYQNGRLEDRWTGHDREITKVCYGASCNGMFSASRDKTIKMWQRGNSH 266

Query: 218 CRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRADQELTAYSQESIICGITSVA 277
             + F GH+  + AI    +   +C+GS D + R++D+     L   +    +  +T V 
Sbjct: 267 SIRDFIGHDMVVTAIHLNTDNTLLCSGSRDNTVRIWDVETGACLRQNNIPQNL--VTDVK 440

Query: 278 FSLSGRLLFAGYDDFNCNVWDSLKCERVGILSGHDNR----VSCLGVTADG 324
           +     L+    +D    ++DS     +GI+     +    +SC  VTADG
Sbjct: 441 WLPGSHLIIQAGEDKEVRIYDS---RTLGIVRSFTKKQYIQMSC-DVTADG 581

 Score = 41.2 bits (95), Expect = 6e-04,   Method: Compositional matrix adjust.
 Identities = 27/122 (22%), Positives = 55/122 (45%), Gaps = 6/122 (4%)
 Frame = +3

Query: 183 HTGDCMSLAV------SPDYKLFISGACDASAKLWDVREGTCRQTFTGHESDINAICFFP 236
           H  D +S+A       S    L +SG+ D S  L+D + G     +TGH+ +I  +C+  
Sbjct: 18  HVRDPVSIATLWSA*RSIQPGLCLSGSKDKSVVLYDYQNGRLEDRWTGHDREITKVCYGA 197

Query: 237 NGEAICTGSDDASCRLFDLRADQELTAYSQESIICGITSVAFSLSGRLLFAGYDDFNCNV 296
           +   + + S D + +++       +  +    ++  +T++  +    LL +G  D    +
Sbjct: 198 SCNGMFSASRDKTIKMWQRGNSHSIRDFIGHDMV--VTAIHLNTDNTLLCSGSRDNTVRI 371

Query: 297 WD 298
           WD
Sbjct: 372 WD 377

 Score = 37.4 bits (85), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 26/101 (25%), Positives = 45/101 (44%), Gaps = 3/101 (2%)
 Frame = +3

Query: 243 TGSDDASCRLFDL---RADQELTAYSQESIICGITSVAFSLSGRLLFAGYDDFNCNVWDS 299
           +GS D S  L+D    R +   T + +E     IT V +  S   +F+   D    +W  
Sbjct: 90  SGSKDKSVVLYDYQNGRLEDRWTGHDRE-----ITKVCYGASCNGMFSASRDKTIKMWQR 254

Query: 300 LKCERVGILSGHDNRVSCLGVTADGMAVATGSWDSFLKIWN 340
                +    GHD  V+ + +  D   + +GS D+ ++IW+
Sbjct: 255 GNSHSIRDFIGHDMVVTAIHLNTDNTLLCSGSRDNTVRIWD 377
>26107
          Length = 1338

 Score = 54.3 bits (129), Expect = 6e-08,   Method: Compositional matrix adjust.
 Identities = 44/152 (28%), Positives = 69/152 (45%), Gaps = 3/152 (1%)
 Frame = -3

Query: 153  DDNNIVTSSGDTTCALWDIETGQQKTVFVGHTGDCMSLAVSPDYKLF-ISGACDASAKLW 211
            +D+  +T+SGD T ALWD+ET  + T F+GH     S+A  P       SGA D    LW
Sbjct: 1054 NDSQCLTASGDQTVALWDVETTTKVTTFIGHKCSVRSVASCPSSPAQCASGARDGHIMLW 875

Query: 212  DVREGTCRQTFTGHE--SDINAICFFPNGEAICTGSDDASCRLFDLRADQELTAYSQESI 269
            D R    R+    H+  S ++ +C     +     S  A  R     A  +    +Q+S+
Sbjct: 874  DSRVNKKRE----HQPCSQVHQVCPQSGHQ-----SKPAKHRRIHRAAGPKGVMDTQQSV 722

Query: 270  ICGITSVAFSLSGRLLFAGYDDFNCNVWDSLK 301
             C    V +     ++ +G +D    +WD+ K
Sbjct: 721  TC----VLYQTDNLIISSGANDGCVKMWDTRK 638

 Score = 42.4 bits (98), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 43/182 (23%), Positives = 77/182 (42%), Gaps = 20/182 (10%)
 Frame = -3

Query: 101 MTCAYAPSGNFVACGGLDNMC-SIYNLKSREGNVKVSRELSAHT-----------GYLSC 148
           +TC    + N +   G ++ C  +++ +    N   S  +  HT           G ++ 
Sbjct: 724 VTCVLYQTDNLIISSGANDGCVKMWDTRKWYTNTTTSLPVPVHTFDYPGHMRRLKGIVTM 545

Query: 149 CRFLDDNNIVTSSGDTTCALWDIETGQ----QKTVFVGHTGDCMSL--AVSPDYKLFISG 202
           C     + +  S  D     + +  GQ    Q+ V+ GH  D   +  A+SPD K  +SG
Sbjct: 544 CMDPWKSQLFVSYTDNKVYRYQL-AGQYREPQEYVYAGHRNDTFFVRCAISPDGKYLLSG 368

Query: 203 ACDASAKLWDVREGTCRQTF-TGHESDINAICFFPNGE-AICTGSDDASCRLFDLRADQE 260
           +   +  +W+V +   R  F  GH  D++A+ +       + T SDD S R++   A + 
Sbjct: 367 SGRNTGVIWEVDKPNKRPLFLIGHTEDVSAVDWCSTDVCKLATVSDDRSLRIWRPDARER 188

Query: 261 LT 262
            T
Sbjct: 187 HT 182

 Score = 36.6 bits (83), Expect = 0.014,   Method: Compositional matrix adjust.
 Identities = 32/148 (21%), Positives = 60/148 (40%), Gaps = 7/148 (4%)
 Frame = -3

Query: 200  ISGACDASAKLWDVREGTCRQTFTGHESDINAICFFPNGEAIC-TGSDDASCRLFDLRAD 258
            ++ + D +  LWDV   T   TF GH+  + ++   P+  A C +G+ D    L+D R +
Sbjct: 1039 LTASGDQTVALWDVETTTKVTTFIGHKCSVRSVASCPSSPAQCASGARDGHIMLWDSRVN 860

Query: 259  QELTAYSQESIICGITSVAFSLSGRLLFAGYDDFNCNVWDSLKCERVGILSGH------D 312
            ++     +E   C         SG                  K  R+   +G        
Sbjct: 859  KK-----REHQPCSQVHQVCPQSGHQS------------KPAKHRRIHRAAGPKGVMDTQ 731

Query: 313  NRVSCLGVTADGMAVATGSWDSFLKIWN 340
              V+C+    D + +++G+ D  +K+W+
Sbjct: 730  QSVTCVLYQTDNLIISSGANDGCVKMWD 647
>12574
          Length = 521

 Score = 54.3 bits (129), Expect = 7e-08,   Method: Compositional matrix adjust.
 Identities = 32/108 (29%), Positives = 50/108 (46%), Gaps = 1/108 (0%)
 Frame = +3

Query: 139 LSAHTGYLSCCRFLDDNN-IVTSSGDTTCALWDIETGQQKTVFVGHTGDCMSLAVSPDYK 197
           L+ HT  LS  +F  + + + +SS D    +W    G+ +    GH      +A S D K
Sbjct: 174 LAGHTKALSAVKFSPNGDWLASSSADKLIKIWGAYDGKFEKTIAGHKLGLSDVAWSSDSK 353

Query: 198 LFISGACDASAKLWDVREGTCRQTFTGHESDINAICFFPNGEAICTGS 245
           L  S + D + K+W+   G C +T  GH + +    F P    I +GS
Sbjct: 354 LLCSASDDKTLKIWEFSTGKCMKTLKGHSNYVFCCNFNPQSNLIVSGS 497

 Score = 48.5 bits (114), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 24/81 (29%), Positives = 42/81 (51%)
 Frame = +3

Query: 37  LEVVGRVQMRTRRTLRGHLAKIYAMHWATDSKLLVSASQDGKLIVWDTYTTNKVHAIPLR 96
           +++ G    +  +T+ GH   +  + W++DSKLL SAS D  L +W+  T   +  +   
Sbjct: 258 IKIWGAYDGKFEKTIAGHKLGLSDVAWSSDSKLLCSASDDKTLKIWEFSTGKCMKTLKGH 437

Query: 97  SSWVMTCAYAPSGNFVACGGL 117
           S++V  C + P  N +  G L
Sbjct: 438 SNYVFCCNFNPQSNLIVSGSL 500

 Score = 46.6 bits (109), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 29/118 (24%), Positives = 55/118 (46%), Gaps = 3/118 (2%)
 Frame = +3

Query: 217 TCRQTFTGHESDINAICFFPNGEAICTGSDDASCRL---FDLRADQELTAYSQESIICGI 273
           T + T  GH   ++A+ F PNG+ + + S D   ++   +D + ++ +  +       G+
Sbjct: 159 TLKFTLAGHTKALSAVKFSPNGDWLASSSADKLIKIWGAYDGKFEKTIAGHK-----LGL 323

Query: 274 TSVAFSLSGRLLFAGYDDFNCNVWDSLKCERVGILSGHDNRVSCLGVTADGMAVATGS 331
           + VA+S   +LL +  DD    +W+    + +  L GH N V C         + +GS
Sbjct: 324 SDVAWSSDSKLLCSASDDKTLKIWEFSTGKCMKTLKGHSNYVFCCNFNPQSNLIVSGS 497

 Score = 41.6 bits (96), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 18/79 (22%), Positives = 39/79 (49%)
 Frame = +3

Query: 177 KTVFVGHTGDCMSLAVSPDYKLFISGACDASAKLWDVREGTCRQTFTGHESDINAICFFP 236
           K    GHT    ++  SP+     S + D   K+W   +G   +T  GH+  ++ + +  
Sbjct: 165 KFTLAGHTKALSAVKFSPNGDWLASSSADKLIKIWGAYDGKFEKTIAGHKLGLSDVAWSS 344

Query: 237 NGEAICTGSDDASCRLFDL 255
           + + +C+ SDD + ++++ 
Sbjct: 345 DSKLLCSASDDKTLKIWEF 401

 Score = 37.0 bits (84), Expect = 0.013,   Method: Compositional matrix adjust.
 Identities = 31/152 (20%), Positives = 57/152 (37%)
 Frame = +3

Query: 9   QEAEQLKKQIADARKACADITLAELVSGLEVVGRVQMRTRRTLRGHLAKIYAMHWATDSK 68
           +E+       AD + A A  T     S  +   +     + TL GH   + A+ ++ +  
Sbjct: 57  EESRGAGGDTADGKHAPASATSGTKSSATQ---KPTYTLKFTLAGHTKALSAVKFSPNGD 227

Query: 69  LLVSASQDGKLIVWDTYTTNKVHAIPLRSSWVMTCAYAPSGNFVACGGLDNMCSIYNLKS 128
            L S+S D  + +W  Y       I      +   A++     +     D    I+   +
Sbjct: 228 WLASSSADKLIKIWGAYDGKFEKTIAGHKLGLSDVAWSSDSKLLCSASDDKTLKIWEFST 407

Query: 129 REGNVKVSRELSAHTGYLSCCRFLDDNNIVTS 160
                K  + L  H+ Y+ CC F   +N++ S
Sbjct: 408 G----KCMKTLKGHSNYVFCCNFNPQSNLIVS 491
>13278
          Length = 870

 Score = 53.5 bits (127), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 29/100 (29%), Positives = 49/100 (49%)
 Frame = +1

Query: 157 IVTSSGDTTCALWDIETGQQKTVFVGHTGDCMSLAVSPDYKLFISGACDASAKLWDVREG 216
           + ++S D+T  LW++E G        H     S+A SPD K   SG+ D    +W+V+ G
Sbjct: 121 LASASFDSTVRLWEVERGLCLHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNVQTG 300

Query: 217 TCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLR 256
           +   ++ G    I  +C+   G+ +   + D S  + DLR
Sbjct: 301 SLVHSYKG-TGGIFEVCWNHRGDKVGASASDGSVFVLDLR 417

 Score = 47.8 bits (112), Expect = 7e-06,   Method: Compositional matrix adjust.
 Identities = 19/73 (26%), Positives = 42/73 (57%), Gaps = 1/73 (1%)
 Frame = +1

Query: 193 SPDYKLFISGAC-DASAKLWDVREGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCR 251
           +P+  L ++ A  D++ +LW+V  G C  T T H+  + ++ F P+G+ + +GS D    
Sbjct: 100 NPNTSLILASASFDSTVRLWEVERGLCLHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVH 279

Query: 252 LFDLRADQELTAY 264
           +++++    + +Y
Sbjct: 280 IWNVQTGSLVHSY 318

 Score = 35.0 bits (79), Expect = 0.048,   Method: Compositional matrix adjust.
 Identities = 20/81 (24%), Positives = 38/81 (46%), Gaps = 9/81 (11%)
 Frame = +1

Query: 57  KIYAMHWATD---------SKLLVSASQDGKLIVWDTYTTNKVHAIPLRSSWVMTCAYAP 107
           +IY + W+           S +L SAS D  + +W+      +H +      V + A++P
Sbjct: 55  EIYTIKWSPTGPGTSNPNTSLILASASFDSTVRLWEVERGLCLHTLTKHQEPVYSVAFSP 234

Query: 108 SGNFVACGGLDNMCSIYNLKS 128
            G ++A G  D    I+N+++
Sbjct: 235 DGKYLASGSFDKCVHIWNVQT 297

 Score = 29.3 bits (64), Expect = 2.6,   Method: Compositional matrix adjust.
 Identities = 14/44 (31%), Positives = 24/44 (54%)
 Frame = +1

Query: 49  RTLRGHLAKIYAMHWATDSKLLVSASQDGKLIVWDTYTTNKVHA 92
            TL  H   +Y++ ++ D K L S S D  + +W+  T + VH+
Sbjct: 184 HTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNVQTGSLVHS 315
>03395
          Length = 2795

 Score = 53.1 bits (126), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 40/168 (23%), Positives = 70/168 (41%), Gaps = 2/168 (1%)
 Frame = +2

Query: 51  LRGHLAKIYAMHWATDSKLLVSASQDGKLIVWDTYTTNKVHAIPLRSSWVMTCAYAPSGN 110
           ++ H  K+ A+   T+ +  VSAS DG  I+WD   TN    I L ++      +     
Sbjct: 134 MKEHKGKVTAIQIHTNDRCCVSASTDGSTIIWD-LITNTRSQIVLANTLFKCVCFGGKDL 310

Query: 111 FVACGGLDNMCSIYNLKSREGNVKVSREL-SAHTGYLSCCRF-LDDNNIVTSSGDTTCAL 168
            +   G D+    + +    G+  + REL  + TG ++      D   I+T   D+   L
Sbjct: 311 HILTSGTDHKIGYWEV----GDGGLLRELEGSQTGAINTIDIDRDGQTILTGGEDSLLKL 478

Query: 169 WDIETGQQKTVFVGHTGDCMSLAVSPDYKLFISGACDASAKLWDVREG 216
           W    G+     +GH+       + P+    +SG  D +  +W   +G
Sbjct: 479 WRYNEGEVTHTGIGHSNQITKARICPNRHYIVSGGEDGALHIWKFPDG 622

 Score = 39.7 bits (91), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 39/191 (20%), Positives = 75/191 (39%), Gaps = 8/191 (4%)
 Frame = +2

Query: 157 IVTSSGDTTCALWDIE----TGQQKTVFVG----HTGDCMSLAVSPDYKLFISGACDASA 208
           +V+  G+    +WDI     TG+ +   V     H G   ++ +  + +  +S + D S 
Sbjct: 41  LVSGGGEGQVRVWDIVKDMLTGKTRGDLVANMKEHKGKVTAIQIHTNDRCCVSASTDGST 220

Query: 209 KLWDVREGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRADQELTAYSQES 268
            +WD+   T  Q    + +    +CF      I T   D     +++  D  L    + S
Sbjct: 221 IIWDLITNTRSQIVLAN-TLFKCVCFGGKDLHILTSGTDHKIGYWEV-GDGGLLRELEGS 394

Query: 269 IICGITSVAFSLSGRLLFAGYDDFNCNVWDSLKCERVGILSGHDNRVSCLGVTADGMAVA 328
               I ++     G+ +  G +D    +W   + E      GH N+++   +  +   + 
Sbjct: 395 QTGAINTIDIDRDGQTILTGGEDSLLKLWRYNEGEVTHTGIGHSNQITKARICPNRHYIV 574

Query: 329 TGSWDSFLKIW 339
           +G  D  L IW
Sbjct: 575 SGGEDGALHIW 607
>01805
          Length = 2124

 Score = 52.0 bits (123), Expect = 4e-07,   Method: Compositional matrix adjust.
 Identities = 66/269 (24%), Positives = 110/269 (40%), Gaps = 34/269 (12%)
 Frame = -1

Query: 64  ATDSKLLVSASQDGKLIVWDTYTTNK------VH------AIPLRSSWVMTCAY--APSG 109
           ATD+ +L    Q G L V D Y  N+      VH      + PL   W+    Y  AP G
Sbjct: 897 ATDNLILCGRCQ-GDLSVLDVYVYNEDNNQLYVHHDYLLSSFPLALEWLNFDGYDNAP-G 724

Query: 110 NFVACGGLDNMCSIYNLKSREG-------------NVKVSRELSAHTGYLSCCRFLDDNN 156
           NFVA G ++ +  I++L   E                K  ++  + TG+      L  N 
Sbjct: 723 NFVAIGSMEPVIEIWDLDIMESVGPTLTLGSKPKKTKKKMKQKESVTGHTQAVLDLSWNR 544

Query: 157 -----IVTSSGDTTCALWDIETGQQKTVFVGHTGDCMSLAVSP-DYKLFISGACDASAKL 210
                + ++S DTT ALWD+  G+    F  H+ +       P + +  ++G+ D + K+
Sbjct: 543 NARHVLASASADTTVALWDLSEGKMAMNFTQHSREVQCCNWHPQEEQTLLTGSFDNTVKV 364

Query: 211 WDVREG-TCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRADQELTAYSQESI 269
            D R   TC +++T       A+    N   +   +D      FD+R ++ + +    S 
Sbjct: 363 VDCRSAETCHKSWTVEGEVEKAVWNHHNPLQLLACTDKGMVYCFDIRHEKPVFSVGAHSS 184

Query: 270 ICGITSVAFSLSGRLLFAGYDDFNCNVWD 298
                 ++  + G L+    +D    VWD
Sbjct: 183 CVTGVCLSSQIPG-LMITTSEDKTMKVWD 100
>10162
          Length = 1629

 Score = 48.9 bits (115), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 40/157 (25%), Positives = 69/157 (43%), Gaps = 11/157 (7%)
 Frame = +3

Query: 193 SPDYKLFISGACDASAKLWDVREGTCRQTFT--------GHESDINAICFFPNGEAICTG 244
           S D  L +SG  DA+AK+++V  G     F           ++ + ++ F P      T 
Sbjct: 396 SADNALIMSGCADATAKVFNVSSGKLXSAFNCAASQDSQDKDNSVESVAFCPVSPYAATA 575

Query: 245 SDDASCRLFDLRADQELTAYSQESIICGITSVAFSLSGRLLFAGYDDFNCNVWDSLKCER 304
           ++  S +++DL       ++     +C +    +S S  LL+    D    VWD+     
Sbjct: 576 TNSGSVQVWDLPTSVARHSFQHPEGVCKLQ---WSSSTALLYTACLDGVMRVWDARSGAS 746

Query: 305 VGILSGHDNRVSCL---GVTADGMAVATGSWDSFLKI 338
             +L+GH  R SC+    VT DG  + +GS D   ++
Sbjct: 747 KAVLTGH-ARNSCILDFDVTRDGTCLVSGSEDGTARV 854

 Score = 37.4 bits (85), Expect = 0.009,   Method: Compositional matrix adjust.
 Identities = 24/97 (24%), Positives = 42/97 (43%), Gaps = 2/97 (2%)
 Frame = +3

Query: 159 TSSGDTTCALWDIETGQQKTVFVGHTGDCMSLAVSPDYKLFISGACDASAKLWDVREGTC 218
           T++   +  +WD+ T   +  F    G C  L  S    L  +   D   ++WD R G  
Sbjct: 570 TATNSGSVQVWDLPTSVARHSFQHPEGVC-KLQWSSSTALLYTACLDGVMRVWDARSGAS 746

Query: 219 RQTFTGHESDINAICF--FPNGEAICTGSDDASCRLF 253
           +   TGH  +   + F    +G  + +GS+D + R+ 
Sbjct: 747 KAVLTGHARNSCILDFDVTRDGTCLVSGSEDGTARVL 857

 Score = 28.9 bits (63), Expect = 2.9,   Method: Compositional matrix adjust.
 Identities = 22/105 (20%), Positives = 38/105 (36%), Gaps = 2/105 (1%)
 Frame = +3

Query: 168 LWDIETGQQKTVFVGHTGDCMSLAVSPDYKLFISGACDASAKLWDVREGTCRQTFTGHES 227
           +W  E G   T    H G            + ++G       LW V      +       
Sbjct: 9   IWSYECGSDITWLQWHGG----------AHVLLAGTQGGEVWLWQVPSQDYSKMKMLQSH 158

Query: 228 DINAIC--FFPNGEAICTGSDDASCRLFDLRADQELTAYSQESII 270
              ++C    PNG+ +C G  D   +L+DL+    +  + Q S++
Sbjct: 159 GQPSLCGKILPNGKYVCVGYSDGVVKLWDLKTGTAVHTW-QHSVM 290
>37180
          Length = 681

 Score = 48.1 bits (113), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 22/79 (27%), Positives = 41/79 (51%), Gaps = 1/79 (1%)
 Frame = +1

Query: 179 VFVGHTGDCMSLAVSPDYKLFISGACDASAKLWDVREGTCR-QTFTGHESDINAICFFPN 237
           V  GH  +   +   P  +L ++ + D + +LWD R+       F GH   + +   F +
Sbjct: 4   VLNGHDQELSDVHAHPTQRLVVTSSKDMTFRLWDFRDSALLVNVFQGHTQPVTS-AVFAS 180

Query: 238 GEAICTGSDDASCRLFDLR 256
           G+ + +GSDD + R++D+R
Sbjct: 181 GDKVVSGSDDRTVRVWDMR 237

 Score = 37.7 bits (86), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 22/59 (37%), Positives = 33/59 (55%), Gaps = 1/59 (1%)
 Frame = +1

Query: 157 IVTSSGDTTCALWDI-ETGQQKTVFVGHTGDCMSLAVSPDYKLFISGACDASAKLWDVR 214
           +VTSS D T  LWD  ++     VF GHT    S   +   K+ +SG+ D + ++WD+R
Sbjct: 64  VVTSSKDMTFRLWDFRDSALLVNVFQGHTQPVTSAVFASGDKV-VSGSDDRTVRVWDMR 237

 Score = 30.4 bits (67), Expect = 0.99,   Method: Compositional matrix adjust.
 Identities = 20/91 (21%), Positives = 42/91 (46%)
 Frame = +1

Query: 51  LRGHLAKIYAMHWATDSKLLVSASQDGKLIVWDTYTTNKVHAIPLRSSWVMTCAYAPSGN 110
           L GH  ++  +H     +L+V++S+D    +WD   +  +  +    +  +T A   SG+
Sbjct: 7   LNGHDQELSDVHAHPTQRLVVTSSKDMTFRLWDFRDSALLVNVFQGHTQPVTSAVFASGD 186

Query: 111 FVACGGLDNMCSIYNLKSREGNVKVSRELSA 141
            V  G  D    ++++++    +   R  SA
Sbjct: 187 KVVSGSDDRTVRVWDMRNMRSPIATIRTDSA 279
>11493
          Length = 535

 Score = 47.4 bits (111), Expect = 7e-06,   Method: Compositional matrix adjust.
 Identities = 33/129 (25%), Positives = 55/129 (42%), Gaps = 5/129 (3%)
 Frame = -2

Query: 128 SREGNVKVSRELS--AHTGYLSCCRFLDDNNIVTSSGD-TTCALWDI--ETGQQKTVFVG 182
           S+ GN     +L       Y+   + L D   +   G+ +  ++WD+   T + K     
Sbjct: 390 SQPGNKNPVSQLDCLQRDNYIRSVKLLPDGRTLIVGGEASNLSIWDLASPTPRIKAELTS 211

Query: 183 HTGDCMSLAVSPDYKLFISGACDASAKLWDVREGTCRQTFTGHESDINAICFFPNGEAIC 242
               C +LA+SPD K+  S   D +  +WD+      + F GH    + I   P+G  + 
Sbjct: 210 AAPACYALAISPDSKVCFSCCSDGNIAVWDLHNEILVRQFQGHTDGASCIDISPDGSRLW 31

Query: 243 TGSDDASCR 251
           TG  D + R
Sbjct: 30  TGGLDNTVR 4

 Score = 43.1 bits (100), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 28/134 (20%), Positives = 58/134 (43%), Gaps = 5/134 (3%)
 Frame = -2

Query: 209 KLWDVREGTCRQTFTG-----HESDINAICFFPNGEAICTGSDDASCRLFDLRADQELTA 263
           K+WD+ +   +   +       ++ I ++   P+G  +  G + ++  ++DL +      
Sbjct: 405 KVWDISQPGNKNPVSQLDCLQRDNYIRSVKLLPDGRTLIVGGEASNLSIWDLASPTPRIK 226

Query: 264 YSQESIICGITSVAFSLSGRLLFAGYDDFNCNVWDSLKCERVGILSGHDNRVSCLGVTAD 323
               S      ++A S   ++ F+   D N  VWD      V    GH +  SC+ ++ D
Sbjct: 225 AELTSAAPACYALAISPDSKVCFSCCSDGNIAVWDLHNEILVRQFQGHTDGASCIDISPD 46

Query: 324 GMAVATGSWDSFLK 337
           G  + TG  D+ ++
Sbjct: 45  GSRLWTGGLDNTVR 4

 Score = 33.1 bits (74), Expect = 0.16,   Method: Compositional matrix adjust.
 Identities = 21/74 (28%), Positives = 31/74 (41%)
 Frame = -2

Query: 46  RTRRTLRGHLAKIYAMHWATDSKLLVSASQDGKLIVWDTYTTNKVHAIPLRSSWVMTCAY 105
           R +  L       YA+  + DSK+  S   DG + VWD +    V      +        
Sbjct: 234 RIKAELTSAAPACYALAISPDSKVCFSCCSDGNIAVWDLHNEILVRQFQGHTDGASCIDI 55

Query: 106 APSGNFVACGGLDN 119
           +P G+ +  GGLDN
Sbjct: 54  SPDGSRLWTGGLDN 13
>01598
          Length = 1545

 Score = 45.1 bits (105), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 36/127 (28%), Positives = 59/127 (46%), Gaps = 15/127 (11%)
 Frame = +1

Query: 104  AYAPSGNFVACGGLDNMCSIYNLKS----REGNVKVS------RELSAHTGYLSCCRFLD 153
            A +P  +++A  G D +  + +L S    REG+ + S      RELS H+  ++   +  
Sbjct: 1153 AGSPCCHWLAAAGNDQVIHVVDLASVFAEREGDKETSLILTSLRELSGHSQRVTDMSWSP 1332

Query: 154  --DNNIVTSSGDTTCALWDIETGQQKTVFVGHTG---DCMSLAVSPDYKLFISGACDASA 208
              D  +V+   D    +WD++ G     F GH G    C    + PD  L ++G  DAS 
Sbjct: 1333 HHDARLVSVGYDAEAFVWDVQKGTALAQFKGHMGRLLTCQFSGLDPD--LVMTGGSDASV 1506

Query: 209  KLWDVRE 215
             +W V +
Sbjct: 1507 HVWRVSQ 1527

 Score = 38.9 bits (89), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 45/204 (22%), Positives = 75/204 (36%), Gaps = 8/204 (3%)
 Frame = +1

Query: 60  AMHW-ATDSKLLVSASQDGKLIVWD-TYTTNKVHAIPLRSSWVMTCAYAPSGNFVACGGL 117
           A+HW  ++ + LVS+S  G L++W   YT  + +          T  Y P          
Sbjct: 241 AIHWLKSNPEQLVSSSSGGDLLLWSLRYTKGQAYQT------FQTSDYRP---------- 372

Query: 118 DNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFLDDNNIVTSSGDTTCALWDIETGQQK 177
            +M  ++N+                     C    D   + T + D    LWD+ET +  
Sbjct: 373 -HMRPVFNI---------------------CASGPDSKTLCTFAQDRQVVLWDLETMEAV 486

Query: 178 TVFVGHTGDCMSLAVSP-DYKLFISGACDASAKLWDVREGTCRQTFT----GHESDINAI 232
                  G    +  SP D      G  D+  + W++   T     T    G +S + A+
Sbjct: 487 ASMATLGGHVYCVRTSPIDPGRVAVGVGDSMIRTWNMSNKTNPYDVTTLWQGIKSKVTAV 666

Query: 233 CFFPNGEA-ICTGSDDASCRLFDL 255
            + P  E  +  G+DD    +FD+
Sbjct: 667 AWHPTKEGWLGFGTDDGRIGVFDV 738

 Score = 35.4 bits (80), Expect = 0.031,   Method: Compositional matrix adjust.
 Identities = 23/75 (30%), Positives = 37/75 (49%), Gaps = 3/75 (4%)
 Frame = +1

Query: 182  GHTGDCMSLAVSPDYKL-FISGACDASAKLWDVREGTCRQTFTGHESDINAICFFP--NG 238
            GH+     ++ SP +    +S   DA A +WDV++GT    F GH   +   C F   + 
Sbjct: 1294 GHSQRVTDMSWSPHHDARLVSVGYDAEAFVWDVQKGTALAQFKGHMGRL-LTCQFSGLDP 1470

Query: 239  EAICTGSDDASCRLF 253
            + + TG  DAS  ++
Sbjct: 1471 DLVMTGGSDASVHVW 1515
>19498
          Length = 903

 Score = 44.7 bits (104), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 42/185 (22%), Positives = 74/185 (40%), Gaps = 22/185 (11%)
 Frame = -1

Query: 119 NMCSIYNLKSREGNVKVSR---ELSAHTGYLSCCRFLDDNNIVTSSG-DTTCALWDIETG 174
           NM  I + K  E +  V R   ++ +H G ++C R+ ++   + S G D    +W I  G
Sbjct: 864 NMAPIRDEK-EEADDDVPRVLCQMDSHLGCVNCVRWSENGKFLASGGDDKLIMIWQISRG 688

Query: 175 -----------------QQKTVFVGHTGDCMSLAVSPDYKLFISGACDASAKLWDVREGT 217
                            +      GH GD + LA SP      S + D +  +W+  + +
Sbjct: 687 FGSGKSFGSNVTILEHWRSVATLRGHAGDVLDLAWSPQDLWLASCSVDNTIVVWNALKFS 508

Query: 218 CR-QTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRADQELTAYSQESIICGITSV 276
            +     GH   +  + + P G  + + SDD + R++     +E T        CG T+ 
Sbjct: 507 EQVAVIRGHAGMVKGVTWDPVGRYLASQSDDKTLRVWRTSDWKEETCVKSCFKECGGTTH 328

Query: 277 AFSLS 281
              L+
Sbjct: 327 VLRLN 313

 Score = 34.7 bits (78), Expect = 0.053,   Method: Compositional matrix adjust.
 Identities = 20/80 (25%), Positives = 35/80 (43%), Gaps = 1/80 (1%)
 Frame = -1

Query: 46  RTRRTLRGHLAKIYAMHWATDSKLLVSASQDGKLIVWDTYT-TNKVHAIPLRSSWVMTCA 104
           R+  TLRGH   +  + W+     L S S D  ++VW+    + +V  I   +  V    
Sbjct: 636 RSVATLRGHAGDVLDLAWSPQDLWLASCSVDNTIVVWNALKFSEQVAVIRGHAGMVKGVT 457

Query: 105 YAPSGNFVACGGLDNMCSIY 124
           + P G ++A    D    ++
Sbjct: 456 WDPVGRYLASQSDDKTLRVW 397
>18981
          Length = 407

 Score = 44.7 bits (104), Expect = 6e-05,   Method: Compositional matrix adjust.
 Identities = 34/128 (26%), Positives = 52/128 (40%)
 Frame = -2

Query: 117 LDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFLDDNNIVTSSGDTTCALWDIETGQQ 176
           L N C ++ L+    +V+              C  +    +V+ S D T  +W+++TG+ 
Sbjct: 337 LKNTCLLHTLRGHNDDVE--------------CVCIYGRRVVSGSWDKTLIVWEVDTGRP 200

Query: 177 KTVFVGHTGDCMSLAVSPDYKLFISGACDASAKLWDVREGTCRQTFTGHESDINAICFFP 236
                GHT      AV  D    +SG+ D   + W +  G C  T T  + DI   C   
Sbjct: 199 VHQLHGHTEAIT--AVQFDEGKAVSGSADGDVRTWALDTGQCLLTMTTGQ-DIEVYCVVY 29

Query: 237 NGEAICTG 244
           N E I  G
Sbjct: 28  NQEVIAAG 5

 Score = 35.4 bits (80), Expect = 0.034,   Method: Compositional matrix adjust.
 Identities = 30/127 (23%), Positives = 61/127 (48%), Gaps = 5/127 (3%)
 Frame = -2

Query: 197 KLFISGACDASAKLWDVREGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDL- 255
            + IS A D + ++W ++      T  GH  D+  +C +  G  + +GS D +  ++++ 
Sbjct: 385 NMIISAATDRTLRVWCLKNTCLLHTLRGHNDDVECVCIY--GRRVVSGSWDKTLIVWEVD 212

Query: 256 --RADQELTAYSQESIICGITSVAFSLSGRLLFAGYDDFNCNVW--DSLKCERVGILSGH 311
             R   +L  +++      IT+V F   G+ + +G  D +   W  D+ +C  + + +G 
Sbjct: 211 TGRPVHQLHGHTE-----AITAVQFD-EGKAV-SGSADGDVRTWALDTGQC-LLTMTTGQ 56

Query: 312 DNRVSCL 318
           D  V C+
Sbjct: 55  DIEVYCV 35

 Score = 28.5 bits (62), Expect = 3.8,   Method: Compositional matrix adjust.
 Identities = 17/63 (26%), Positives = 27/63 (42%)
 Frame = -2

Query: 278 FSLSGRLLFAGYDDFNCNVWDSLKCERVGILSGHDNRVSCLGVTADGMAVATGSWDSFLK 337
             L   ++ +   D    VW       +  L GH++ V C+ +   G  V +GSWD  L 
Sbjct: 400 IHLLDNMIISAATDRTLRVWCLKNTCLLHTLRGHNDDVECVCIY--GRRVVSGSWDKTLI 227

Query: 338 IWN 340
           +W 
Sbjct: 226 VWE 218
>03387
          Length = 1891

 Score = 44.3 bits (103), Expect = 8e-05,   Method: Compositional matrix adjust.
 Identities = 53/233 (22%), Positives = 95/233 (40%), Gaps = 28/233 (12%)
 Frame = +1

Query: 51  LRGHLAKIYAMHWATD-SKLLVSASQDGKLIVWDTYTTNK------VHAIPLRSSWVM-- 101
           L+GH  + Y + W  + +  L+SAS D  + +WD  +T +       H I    + V+  
Sbjct: 349 LKGHQKEGYGLSWNPNLNGHLLSASDDHTICLWDINSTQRESRVVDAHTIFTGHTSVVED 528

Query: 102 TCAYAPSGNFVACGGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFLDDNNIV--T 159
              +    +       D    I++ +S   + K S  + AHT  ++C  F   +  +  T
Sbjct: 529 VAWHLLHESLFGSVADDQKLMIWDTRSNTTS-KPSHVVDAHTAEVNCLSFNPYSEFILAT 705

Query: 160 SSGDTTCALWDIETGQQK-TVFVGHTGDCMSLAVSP-DYKLFISGACDASAKLWDV---- 213
            S D T ALWD+   + K   F  H  +   +  SP +  +  S   D    +WD+    
Sbjct: 706 GSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLHVWDLSKIG 885

Query: 214 --------REGTCRQTFT--GHESDINAICFFPNGE-AICTGSDDASCRLFDL 255
                    +G     F   GH + I+   + PN    +C+ S+D   +++ +
Sbjct: 886 EEQLPEDAEDGPPELLFIHGGHTAKISDFSWNPNEPWIVCSVSEDNIMQVWQM 1044
>31864
          Length = 545

 Score = 44.3 bits (103), Expect = 8e-05,   Method: Compositional matrix adjust.
 Identities = 40/172 (23%), Positives = 70/172 (40%), Gaps = 2/172 (1%)
 Frame = +2

Query: 169 WDIETGQQKTVFVG--HTGDCMSLAVSPDYKLFISGACDASAKLWDVREGTCRQTFTGHE 226
           WD+  GQ K V  G  HTG    + +S D  +F++ + D +AKL+D     C +T+   E
Sbjct: 2   WDVRKGQ-KVVDSGVDHTGGINDMQLSKDGTMFVTASKDTTAKLFDSESLMCLKTYKT-E 175

Query: 227 SDINAICFFPNGEAICTGSDDASCRLFDLRADQELTAYSQESIICGITSVAFSLSGRLLF 286
             +N+    P  + +  G                     Q+++    TS     +G+   
Sbjct: 176 RPVNSAAISPILDHVVLGG-------------------GQDAMEVTTTSTK---AGK--- 280

Query: 287 AGYDDFNCNVWDSLKCERVGILSGHDNRVSCLGVTADGMAVATGSWDSFLKI 338
                F+   +  +  E    L GH   ++ L    DG + A+G  D F+++
Sbjct: 281 -----FDSRFFHLIYEEEFARLKGHFGPINSLAFHPDGKSYASGGEDGFVRV 421
>27806
          Length = 419

 Score = 43.9 bits (102), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 20/78 (25%), Positives = 41/78 (52%)
 Frame = -1

Query: 194 PDYKLFISGACDASAKLWDVREGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLF 253
           P + +  + + D +A+++ +  G C  T+ GH+  +NA+ F P  + + T S D +  ++
Sbjct: 395 PGHPIIGTASADHTARIYSIETGACVLTYGGHQGSVNAVRFHPGQDLVLTASGDHTAHVW 216

Query: 254 DLRADQELTAYSQESIIC 271
             RA      +SQ S++ 
Sbjct: 215 --RAQ-----FSQPSLMS 183

 Score = 33.5 bits (75), Expect = 0.12,   Method: Compositional matrix adjust.
 Identities = 17/55 (30%), Positives = 28/55 (50%)
 Frame = -1

Query: 157 IVTSSGDTTCALWDIETGQQKTVFVGHTGDCMSLAVSPDYKLFISGACDASAKLW 211
           I T+S D T  ++ IETG     + GH G   ++   P   L ++ + D +A +W
Sbjct: 380 IGTASADHTARIYSIETGACVLTYGGHQGSVNAVRFHPGQDLVLTASGDHTAHVW 216
>14500
          Length = 1238

 Score = 35.8 bits (81), Expect(2) = 1e-04,   Method: Compositional matrix adjust.
 Identities = 23/98 (23%), Positives = 43/98 (43%), Gaps = 2/98 (2%)
 Frame = +3

Query: 244 GSDDASCRLFDLRADQELTAYSQESIICGITSVAFSLSGRLLFA--GYDDFNCNVWDSLK 301
           G+ D     ++      L++   +S +C +    +S   R L +  G+      +W    
Sbjct: 264 GTADRHIHFWNCNTGTNLSSVDTKSQVCALL---WSKEHRELISSHGFAQNQLIIWKYPA 434

Query: 302 CERVGILSGHDNRVSCLGVTADGMAVATGSWDSFLKIW 339
             RV  L+GH  RV  + ++ DG  V + + D  L++W
Sbjct: 435 MSRVAELTGHTARVLHMAMSPDGETVVSAAADETLRLW 548

 Score = 26.9 bits (58), Expect(2) = 1e-04,   Method: Compositional matrix adjust.
 Identities = 19/56 (33%), Positives = 27/56 (48%), Gaps = 5/56 (8%)
 Frame = +2

Query: 182 GHTGDCMSLAVSPDYKLFISGACDASAKLW--DVREGTCRQ---TFTGHESDINAI 232
           GH+ +   L  SPD K   SGA D    +W   V  G   Q   TF+ H++ + A+
Sbjct: 53  GHSQEVCGLRWSPDGKYLASGANDNLLCVWPAQVTGGNSTQPLHTFSQHQAAVKAL 220

 Score = 35.8 bits (81), Expect = 0.027,   Method: Compositional matrix adjust.
 Identities = 19/57 (33%), Positives = 25/57 (43%)
 Frame = +2

Query: 41 GRVQMRTRRTLRGHLAKIYAMHWATDSKLLVSASQDGKLIVWDTYTTNKVHAIPLRS 97
          GRV      TL GH  ++  + W+ D K L S + D  L VW    T      PL +
Sbjct: 17 GRVADHHVGTLSGHSQEVCGLRWSPDGKYLASGANDNLLCVWPAQVTGGNSTQPLHT 187

 Score = 33.5 bits (75), Expect = 0.12,   Method: Compositional matrix adjust.
 Identities = 13/44 (29%), Positives = 22/44 (50%)
 Frame = +3

Query: 168 LWDIETGQQKTVFVGHTGDCMSLAVSPDYKLFISGACDASAKLW 211
           +W      +     GHT   + +A+SPD +  +S A D + +LW
Sbjct: 417 IWKYPAMSRVAELTGHTARVLHMAMSPDGETVVSAAADETLRLW 548

 Score = 28.1 bits (61), Expect(2) = 0.25,   Method: Compositional matrix adjust.
 Identities = 21/95 (22%), Positives = 40/95 (42%), Gaps = 2/95 (2%)
 Frame = +3

Query: 161 SGDTTCALWDIETGQQKTVFVGHTGDCMSLAVSPDYKLFISGACDASAKL--WDVREGTC 218
           + D     W+  TG   +     +  C +L  S +++  IS    A  +L  W     + 
Sbjct: 267 TADRHIHFWNCNTGTNLSSVDTKSQVC-ALLWSKEHRELISSHGFAQNQLIIWKYPAMSR 443

Query: 219 RQTFTGHESDINAICFFPNGEAICTGSDDASCRLF 253
               TGH + +  +   P+GE + + + D + RL+
Sbjct: 444 VAELTGHTARVLHMAMSPDGETVVSAAADETLRLW 548

 Score = 23.1 bits (48), Expect(2) = 0.25,   Method: Compositional matrix adjust.
 Identities = 8/28 (28%), Positives = 16/28 (57%)
 Frame = +2

Query: 105 YAPSGNFVACGGLDNMCSIYNLKSREGN 132
           ++P G ++A G  DN+  ++  +   GN
Sbjct: 83  WSPDGKYLASGANDNLLCVWPAQVTGGN 166

 Score = 30.4 bits (67), Expect = 0.95,   Method: Compositional matrix adjust.
 Identities = 15/44 (34%), Positives = 24/44 (54%)
 Frame = +3

Query: 51  LRGHLAKIYAMHWATDSKLLVSASQDGKLIVWDTYTTNKVHAIP 94
           L GH A++  M  + D + +VSA+ D  L +W  +T +K    P
Sbjct: 453 LTGHTARVLHMAMSPDGETVVSAAADETLRLWKCFTVDKEKKRP 584
>12960
          Length = 550

 Score = 43.5 bits (101), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 28/109 (25%), Positives = 46/109 (42%), Gaps = 1/109 (0%)
 Frame = +2

Query: 150 RF-LDDNNIVTSSGDTTCALWDIETGQQKTVFVGHTGDCMSLAVSPDYKLFISGACDASA 208
           RF +D    +T   D +  LW+         ++GH  + +    S D     SG  D + 
Sbjct: 194 RFSVDSRYCMTCGSDKSVKLWNPHRELFLKTYIGHGHEVLDAQGSGDNSQICSGGIDKTV 373

Query: 209 KLWDVREGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRA 257
            L+DV  G   + +  H   +N + F      I +GS D + R +D R+
Sbjct: 374 VLFDVASGQALRKYRDHAGTVNCVKFNEESTVILSGSLDNTVRAWDTRS 520

 Score = 39.7 bits (91), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 26/111 (23%), Positives = 48/111 (43%)
 Frame = +2

Query: 189 SLAVSPDYKLFISGACDASAKLWDVREGTCRQTFTGHESDINAICFFPNGEAICTGSDDA 248
           ++  S D +  ++   D S KLW+       +T+ GH  ++       +   IC+G  D 
Sbjct: 188 AVRFSVDSRYCMTCGSDKSVKLWNPHRELFLKTYIGHGHEVLDAQGSGDNSQICSGGIDK 367

Query: 249 SCRLFDLRADQELTAYSQESIICGITSVAFSLSGRLLFAGYDDFNCNVWDS 299
           +  LFD+ + Q L  Y   +    +  V F+    ++ +G  D     WD+
Sbjct: 368 TVVLFDVASGQALRKYRDHA--GTVNCVKFNEESTVILSGSLDNTVRAWDT 514
>07665
          Length = 435

 Score = 43.1 bits (100), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 29/94 (30%), Positives = 45/94 (47%), Gaps = 7/94 (7%)
 Frame = -2

Query: 211 WDVREGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRADQ-------ELTA 263
           WD+ +G    T   H   INA+CF PN   +C      S +++DL   +       E+ +
Sbjct: 392 WDLNDGKNLYTLE-HNDIINALCFSPNRYWLCVAYG-PSIKIWDLACKKTVEELRPEVVS 219

Query: 264 YSQESIICGITSVAFSLSGRLLFAGYDDFNCNVW 297
            + ++      S+A+S  G+ LFAGY D    VW
Sbjct: 218 PTSKAEQPQCLSLAWSTDGQTLFAGYSDNTIRVW 117
>01249
          Length = 1743

 Score = 43.1 bits (100), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 36/137 (26%), Positives = 60/137 (43%), Gaps = 16/137 (11%)
 Frame = -1

Query: 220  QTFTGHESDINAICFFPNGEA--ICTGSDDASCRLFDLRADQELTAYSQESIICGITSVA 277
            +T   H   I  +     G A  + + S D +C+L+D+ +   L     E+   G+  + 
Sbjct: 1230 RTINAHSEPITGLHVGCGGPAARVASSSSDGTCKLWDMLSGALLRTMVYET---GVGCLI 1060

Query: 278  FSLSGRLLFAGYD--DFNCN----------VWDSLKCERVG--ILSGHDNRVSCLGVTAD 323
                   L AG D  D  C+          V+ S    + G  +L GH + V+CL  ++D
Sbjct: 1059 MDKQEHFLLAGLDNGDILCSPLFGQISQSEVFVSKHTTKAGERVLQGHSDAVTCLAFSSD 880

Query: 324  GMAVATGSWDSFLKIWN 340
            G  +A+GS +  + IWN
Sbjct: 879  GQRLASGSQNGKVIIWN 829

 Score = 34.7 bits (78), Expect = 0.061,   Method: Compositional matrix adjust.
 Identities = 13/36 (36%), Positives = 24/36 (66%)
 Frame = -1

Query: 48  RRTLRGHLAKIYAMHWATDSKLLVSASQDGKLIVWD 83
            R L+GH   +  + +++D + L S SQ+GK+I+W+
Sbjct: 936 ERVLQGHSDAVTCLAFSSDGQRLASGSQNGKVIIWN 829

 Score = 27.7 bits (60), Expect = 6.4,   Method: Compositional matrix adjust.
 Identities = 40/185 (21%), Positives = 65/185 (35%), Gaps = 29/185 (15%)
 Frame = -1

Query: 61   MHWATDSKLLVSASQDGKLIVWD---TYTTNKVHAIPLRSSWVMTCAYAP-SGNFVACGG 116
            + +  D    V A+  G L +WD     TT    A  L+    +     P +G  V CGG
Sbjct: 1353 IQFTDDGSQFVVATSSGHLNIWDFARVVTTTSQRARGLKPGRTINAHSEPITGLHVGCGG 1174

Query: 117  L---------DNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFLDDNNIVT----SSGD 163
                      D  C ++++ S      + R +   TG    C  +D           +GD
Sbjct: 1173 PAARVASSSSDGTCKLWDMLSG----ALLRTMVYETGV--GCLIMDKQEHFLLAGLDNGD 1012

Query: 164  TTCALWDIETGQQKT------------VFVGHTGDCMSLAVSPDYKLFISGACDASAKLW 211
              C+    +  Q +             V  GH+     LA S D +   SG+ +    +W
Sbjct: 1011 ILCSPLFGQISQSEVFVSKHTTKAGERVLQGHSDAVTCLAFSSDGQRLASGSQNGKVIIW 832

Query: 212  DVREG 216
            ++  G
Sbjct: 831  NMESG 817
>10264
          Length = 416

 Score = 42.4 bits (98), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 34/132 (25%), Positives = 59/132 (44%), Gaps = 18/132 (13%)
 Frame = -1

Query: 102 TCAYAPSGNFVACGGLDNMCSIYNLKS---------REGNVKVS------RELSAHTGYL 146
           + A +P  +++A  G D +  + +L S         REG+ +        RELS H+  +
Sbjct: 413 SPAGSPRCHWLAAAGNDQVIHVVDLASVFGEMGATEREGDKETLLILTSLRELSGHSQRV 234

Query: 147 SCCRF--LDDNNIVTSSGDTTCALWDIETGQQKTVFVGHTGDCMSLAVSP-DYKLFISGA 203
           +   +    D  +V+   D    +WD++ G     F GH G  ++   S  D  L ++G 
Sbjct: 233 TDMSWSPHHDARLVSVGYDAEAFVWDVQKGTALAQFKGHMGRLLTCQFSGLDPDLVMTGG 54

Query: 204 CDASAKLWDVRE 215
            DAS  +W V +
Sbjct: 53  SDASVHVWRVSQ 18

 Score = 35.4 bits (80), Expect = 0.031,   Method: Compositional matrix adjust.
 Identities = 23/75 (30%), Positives = 37/75 (49%), Gaps = 3/75 (4%)
 Frame = -1

Query: 182 GHTGDCMSLAVSPDYKL-FISGACDASAKLWDVREGTCRQTFTGHESDINAICFFP--NG 238
           GH+     ++ SP +    +S   DA A +WDV++GT    F GH   +   C F   + 
Sbjct: 251 GHSQRVTDMSWSPHHDARLVSVGYDAEAFVWDVQKGTALAQFKGHMGRL-LTCQFSGLDP 75

Query: 239 EAICTGSDDASCRLF 253
           + + TG  DAS  ++
Sbjct: 74  DLVMTGGSDASVHVW 30
>15780
          Length = 735

 Score = 42.4 bits (98), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 19/59 (32%), Positives = 29/59 (49%)
 Frame = -1

Query: 197 KLFISGACDASAKLWDVREGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDL 255
           K   +   D +  +WD+  GT     T H   + A+CF  +G  + +G  D S RL+DL
Sbjct: 735 KYLSTAGADHTVIVWDIASGTAVAHLTAHTDTVYALCFSRDGTVLASGGMDNSIRLWDL 559

 Score = 37.0 bits (84), Expect = 0.011,   Method: Compositional matrix adjust.
 Identities = 19/55 (34%), Positives = 26/55 (47%)
 Frame = -1

Query: 159 TSSGDTTCALWDIETGQQKTVFVGHTGDCMSLAVSPDYKLFISGACDASAKLWDV 213
           T+  D T  +WDI +G        HT    +L  S D  +  SG  D S +LWD+
Sbjct: 723 TAGADHTVIVWDIASGTAVAHLTAHTDTVYALCFSRDGTVLASGGMDNSIRLWDL 559

 Score = 32.7 bits (73), Expect = 0.22,   Method: Compositional matrix adjust.
 Identities = 22/82 (26%), Positives = 37/82 (45%), Gaps = 6/82 (7%)
 Frame = -1

Query: 68  KLLVSASQDGKLIVWDTYTTNKVHAIPLRSSWVMTCAYAPSGNFVACGGLDNMCSIYNL- 126
           K L +A  D  +IVWD  +   V  +   +  V    ++  G  +A GG+DN   +++L 
Sbjct: 735 KYLSTAGADHTVIVWDIASGTAVAHLTAHTDTVYALCFSRDGTVLASGGMDNSIRLWDLA 556

Query: 127 -----KSREGNVKVSRELSAHT 143
                +  E +  V   LS +T
Sbjct: 555 RVMEEQDPETDSNVPSSLSVNT 490
>01462
          Length = 995

 Score = 41.2 bits (95), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 22/76 (28%), Positives = 35/76 (46%)
 Frame = +2

Query: 161 SGDTTCALWDIETGQQKTVFVGHTGDCMSLAVSPDYKLFISGACDASAKLWDVREGTCRQ 220
           +GD    +WDIE GQ      GH      + +  D +  +S + D + ++WD+R  T  +
Sbjct: 254 AGDRKIHVWDIEAGQYLNAMEGHKDYIHKVVMKNDAQECVSASEDGTVRMWDIRSST--E 427

Query: 221 TFTGHESDINAICFFP 236
           T    E   N +C  P
Sbjct: 428 TVHCLEPSKNELCSRP 475

 Score = 36.6 bits (83), Expect = 0.015,   Method: Compositional matrix adjust.
 Identities = 15/64 (23%), Positives = 31/64 (48%)
 Frame = +2

Query: 197 KLFISGACDASAKLWDVREGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLR 256
           +   +GA D    +WD+  G       GH+  I+ +    + +   + S+D + R++D+R
Sbjct: 236 RRLYAGAGDRKIHVWDIEAGQYLNAMEGHKDYIHKVVMKNDAQECVSASEDGTVRMWDIR 415

Query: 257 ADQE 260
           +  E
Sbjct: 416 SSTE 427

 Score = 36.6 bits (83), Expect = 0.017,   Method: Compositional matrix adjust.
 Identities = 23/77 (29%), Positives = 36/77 (46%), Gaps = 11/77 (14%)
 Frame = +2

Query: 51  LRGHLAKIYAMHWATDSKLLVSASQDGKLIVWDTY-TTNKVHAI----------PLRSSW 99
           + GH   I+ +    D++  VSAS+DG + +WD   +T  VH +          PL   W
Sbjct: 311 MEGHKDYIHKVVMKNDAQECVSASEDGTVRMWDIRSSTETVHCLEPSKNELCSRPLLGKW 490

Query: 100 VMTCAYAPSGNFVACGG 116
           +   A  P   ++ CGG
Sbjct: 491 LRCLALDPEEGWLVCGG 541

 Score = 30.0 bits (66), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 14/58 (24%), Positives = 28/58 (48%)
 Frame = +2

Query: 283 RLLFAGYDDFNCNVWDSLKCERVGILSGHDNRVSCLGVTADGMAVATGSWDSFLKIWN 340
           R L+AG  D   +VWD    + +  + GH + +  + +  D     + S D  +++W+
Sbjct: 236 RRLYAGAGDRKIHVWDIEAGQYLNAMEGHKDYIHKVVMKNDAQECVSASEDGTVRMWD 409
>03734
          Length = 1963

 Score = 40.8 bits (94), Expect = 8e-04,   Method: Compositional matrix adjust.
 Identities = 29/125 (23%), Positives = 55/125 (44%), Gaps = 11/125 (8%)
 Frame = -2

Query: 190  LAVSPDYKLFISGACDASAKLWDVRE--GTCRQTFTGHESD------INAICFFPNGEAI 241
            LA++PD +  +S    +S ++WD+ +  GT   T    E++         +C   N +  
Sbjct: 1143 LAITPDNRYLVSATSVSSLQIWDISDDKGTLLHTVRPEETEEEGRHSFTNLCVSDNSKMA 964

Query: 242  CTGSDDASCRLFDLRADQ---ELTAYSQESIICGITSVAFSLSGRLLFAGYDDFNCNVWD 298
             T +      L+ +   +   +L A SQ++     T+++F+ + R L   Y D     +D
Sbjct: 963  ATSNSGGQVHLYSIAEGEVLCKLPALSQQA-----TAISFTXAARTLLVTYSDHKVMEFD 799

Query: 299  SLKCE 303
              K E
Sbjct: 798  VQKEE 784

 Score = 29.3 bits (64), Expect = 2.6,   Method: Compositional matrix adjust.
 Identities = 17/68 (25%), Positives = 32/68 (47%), Gaps = 2/68 (2%)
 Frame = -2

Query: 168  LWDIETGQ--QKTVFVGHTGDCMSLAVSPDYKLFISGACDASAKLWDVREGTCRQTFTGH 225
            +W +++G   Q+ +  G       LAV  D  + +SG        W+ ++GT    F  H
Sbjct: 1947 IWSVKSGHALQRIIIGGEDTTVWCLAVLGDLTI-VSGDSRGKVCFWNGKQGTRIAHFQSH 1771

Query: 226  ESDINAIC 233
            ++D+  +C
Sbjct: 1770 KADVLTLC 1747
>26939
          Length = 388

 Score = 40.0 bits (92), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 23/85 (27%), Positives = 35/85 (41%)
 Frame = +2

Query: 157 IVTSSGDTTCALWDIETGQQKTVFVGHTGDCMSLAVSPDYKLFISGACDASAKLWDVREG 216
           +V++S D T  +WD+   +       H   C S+     +   ISG+ D + K+W+ R  
Sbjct: 11  LVSASDDKTIRVWDLRNKRCMKTLYAHQHFCTSIDFHKAHPYVISGSVDQTVKVWECR-- 184

Query: 217 TCRQTFTGHESDINAICFFPNGEAI 241
                    E   N IC F N   I
Sbjct: 185 --------*EHSANNICLFLNLNII 235

 Score = 30.0 bits (66), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 16/61 (26%), Positives = 29/61 (47%)
 Frame = +2

Query: 238 GEAICTGSDDASCRLFDLRADQELTAYSQESIICGITSVAFSLSGRLLFAGYDDFNCNVW 297
           G+ + + SDD + R++DLR  + +         C  TS+ F  +   + +G  D    VW
Sbjct: 2   GKYLVSASDDKTIRVWDLRNKRCMKTLYAHQHFC--TSIDFHKAHPYVISGSVDQTVKVW 175

Query: 298 D 298
           +
Sbjct: 176 E 178
>19863
          Length = 502

 Score = 39.7 bits (91), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 18/59 (30%), Positives = 31/59 (52%)
 Frame = +1

Query: 157 IVTSSGDTTCALWDIETGQQKTVFVGHTGDCMSLAVSPDYKLFISGACDASAKLWDVRE 215
           +V+ S D +  +WD+E G QK    GH G    +  S D    +S + D + ++W++ E
Sbjct: 16  LVSGSSDMSIVVWDVENGVQKLRLQGHAGWVNDVHFSQDQCWLLSCSNDNTVRIWNIEE 192

 Score = 33.9 bits (76), Expect = 0.095,   Method: Compositional matrix adjust.
 Identities = 18/85 (21%), Positives = 38/85 (44%)
 Frame = +1

Query: 199 FISGACDASAKLWDVREGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRAD 258
            +SG+ D S  +WDV  G  +    GH   +N + F  +   + + S+D + R++++   
Sbjct: 16  LVSGSSDMSIVVWDVENGVQKLRLQGHAGWVNDVHFSQDQCWLLSCSNDNTVRIWNIEES 195

Query: 259 QELTAYSQESIICGITSVAFSLSGR 283
            ++    +     G+     S  G+
Sbjct: 196 DQIPIVMEHKRAQGLKVTKCSKCGK 270
>04358
          Length = 2430

 Score = 38.9 bits (89), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 64/275 (23%), Positives = 96/275 (34%), Gaps = 73/275 (26%)
 Frame = +1

Query: 139  LSAHTGYLSCCRFL--DDNNIVTSSGDTTCALWDIETGQQKTV--FVGHTG---DCMSLA 191
            L+ H   +S  RFL  D   I+T+S D T  +WD      K V  F G        +S  
Sbjct: 1408 LTGHDDVISSIRFLHTDPGLIMTASHDHTVRIWDPRASVSKEVQRFSGEQNTKCSVLSCD 1587

Query: 192  VSPDYKLFISGAC----DASAKLWDVREGTCRQTFT-GHESDINAICFFPNGE-AICTGS 245
            V+   ++  +G      DA    WD R+      +   H  DI  + F P  E  + TGS
Sbjct: 1588 VNISDRVLCAGTEMSNDDAYLLFWDRRKDKLLGCYEDSHHDDITQVHFGPTSEKTLLTGS 1767

Query: 246  DDASCRLFDLRADQE----LTAYSQESII-----CG------------------------ 272
             D    +FD+    E    ++ Y+ E+ +     CG                        
Sbjct: 1768 TDGLVNVFDVMQTTEDDALMSTYNTEATVERAGWCGPQSQQVYAITHMLSWHVWDTEKDE 1947

Query: 273  ----ITSVAFSLSGRL-------------------LFAGYDDFNCNVWDSLKCERVGIL- 308
                +T +   L G+                    L AG    + +V D    E V ++ 
Sbjct: 1948 DVQQLTDLEQKLQGQCQADYLVDCIPANQSTSPPCLVAGTHTGDLHVLDLSDLEEVKVVR 2127

Query: 309  ---SGHDNRVSCLGVTADGMAVATGSWDSFLKIWN 340
                GH + V CL        + TG  DS L +W+
Sbjct: 2128 SLSGGHTDTVRCLHWDKQTQTLVTGGEDSMLCLWS 2232
>21921
          Length = 1341

 Score = 37.4 bits (85), Expect = 0.009,   Method: Compositional matrix adjust.
 Identities = 16/47 (34%), Positives = 25/47 (53%)
 Frame = -1

Query: 176 QKTVFVGHTGDCMSLAVSPDYKLFISGACDASAKLWDVREGTCRQTF 222
           Q  V+ GHTG   S+   P  +  +SG+ D + + W+V  G C +T 
Sbjct: 507 QALVYKGHTGIVRSICPDPTGQWLVSGSDDGTIRFWEVSSGRCMKTL 367

 Score = 32.3 bits (72), Expect = 0.25,   Method: Compositional matrix adjust.
 Identities = 15/50 (30%), Positives = 26/50 (52%), Gaps = 2/50 (4%)
 Frame = -1

Query: 208 AKLWDVREGTCRQ--TFTGHESDINAICFFPNGEAICTGSDDASCRLFDL 255
            K  D+R     Q   + GH   + +IC  P G+ + +GSDD + R +++
Sbjct: 543 PKPKDLRPFPTTQALVYKGHTGIVRSICPDPTGQWLVSGSDDGTIRFWEV 394
>15118
          Length = 1074

 Score = 36.6 bits (83), Expect = 0.016,   Method: Compositional matrix adjust.
 Identities = 29/143 (20%), Positives = 57/143 (39%), Gaps = 4/143 (2%)
 Frame = +3

Query: 202 GACDASAKLWDVREGTCRQTF---TGHESDINAICFFPNGEAICTGSDDASCRLFDLRA- 257
           G       +++++ G  R +F     H S +  + F      + T   D   + +   + 
Sbjct: 111 GYSSGHLDIYNLQSGKHRGSFGDTVAHVSGVRGVAFDAFNCLLITAGGDCDIKFWRFGSR 290

Query: 258 DQELTAYSQESIICGITSVAFSLSGRLLFAGYDDFNCNVWDSLKCERVGILSGHDNRVSC 317
           D+      +  +  GI+ +       +L    +DF  +V D      V + SGH N ++ 
Sbjct: 291 DRARVLLKELKMSEGISRILLHRDSNMLAVVLEDFTVSVIDVDTLRVVRVFSGHSNSITD 470

Query: 318 LGVTADGMAVATGSWDSFLKIWN 340
           L  + DG  + T S D  ++ W+
Sbjct: 471 LSFSGDGRWLITASMDCTVRTWS 539

 Score = 34.3 bits (77), Expect = 0.071,   Method: Compositional matrix adjust.
 Identities = 40/173 (23%), Positives = 70/173 (40%), Gaps = 7/173 (4%)
 Frame = +3

Query: 109 GNFVACGGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFLDDNN--IVTSSGDTTC 166
           GN+VA G       IYNL+S +       +  AH   +    F D  N  ++T+ GD   
Sbjct: 93  GNYVAVGYSSGHLDIYNLQSGKHRGSFG-DTVAHVSGVRGVAF-DAFNCLLITAGGDCDI 266

Query: 167 ALWDIETGQQKTVFVGHTGDCMSLAVS-----PDYKLFISGACDASAKLWDVREGTCRQT 221
             W   +  +  V +      MS  +S      D  +      D +  + DV      + 
Sbjct: 267 KFWRFGSRDRARVLLKELK--MSEGISRILLHRDSNMLAVVLEDFTVSVIDVDTLRVVRV 440

Query: 222 FTGHESDINAICFFPNGEAICTGSDDASCRLFDLRADQELTAYSQESIICGIT 274
           F+GH + I  + F  +G  + T S D + R + L   + +  ++ E+ +  +T
Sbjct: 441 FSGHSNSITDLSFSGDGRWLITASMDCTVRTWSLVHGRLIDCFAVEAAVTSLT 599
>16199
          Length = 694

 Score = 36.6 bits (83), Expect = 0.016,   Method: Compositional matrix adjust.
 Identities = 14/41 (34%), Positives = 23/41 (56%)
 Frame = +2

Query: 194 PDYKLFISGACDASAKLWDVREGTCRQTFTGHESDINAICF 234
           PD  +F +G  D+  K+WD++E      F GH+  + +I F
Sbjct: 101 PDGLIFATGTEDSVIKIWDLKERANVANFQGHQGPVTSISF 223

 Score = 29.3 bits (64), Expect = 2.6,   Method: Compositional matrix adjust.
 Identities = 15/49 (30%), Positives = 24/49 (48%), Gaps = 1/49 (2%)
 Frame = +2

Query: 146 LSCCRFLDDNNIV-TSSGDTTCALWDIETGQQKTVFVGHTGDCMSLAVS 193
           L+C +F  D  I  T + D+   +WD++       F GH G   S++ S
Sbjct: 80  LTCAQFHPDGLIFATGTEDSVIKIWDLKERANVANFQGHQGPVTSISFS 226

 Score = 28.5 bits (62), Expect = 4.5,   Method: Compositional matrix adjust.
 Identities = 11/26 (42%), Positives = 17/26 (65%)
 Frame = +2

Query: 315 VSCLGVTADGMAVATGSWDSFLKIWN 340
           ++C     DG+  ATG+ DS +KIW+
Sbjct: 80  LTCAQFHPDGLIFATGTEDSVIKIWD 157
>12841
          Length = 1364

 Score = 36.2 bits (82), Expect = 0.020,   Method: Compositional matrix adjust.
 Identities = 48/239 (20%), Positives = 88/239 (36%), Gaps = 14/239 (5%)
 Frame = +1

Query: 54  HLAKIYAMHWATDSK--------LLVSASQDGKLIVWDT---YTTNKVHAIPLRSSWVMT 102
           HL  ++ + W    +        +L+S S DG++  W     + +N +  +    + +  
Sbjct: 697 HLGPVWQIQWIEKERGSGEERAEVLISISTDGRVTQWSIRKGFESNNIMRLKKLPTRMAG 876

Query: 103 CAYAPSGNFVACGGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFLDDNNIVTSSG 162
            A    G          +C  ++  SR+ NV ++       GY+  C             
Sbjct: 877 KAREKKGEAFISRHAGGLC--FDFHSRDLNVYLA---GTEEGYIHKC------------- 1002

Query: 163 DTTCALWDIETGQQKTVFVGHTGDCMSLAVSPDYK-LFISGACDASAKLWDVREGTCRQT 221
             +C+       Q    + GHT     +  SP    +F+S + D S +LW     T   T
Sbjct: 1003--SCSY----NEQYLETYSGHTAPVYHIRWSPFVSDIFLSCSADWSIRLWHQDRTTPILT 1164

Query: 222 FTGHESDINAICFFPNGEAICTGSDDASCRLFDLRADQELTAYSQESIICG--ITSVAF 278
           F      ++ +C+ P    +     + +  ++DL A   L A    +   G  +TSV F
Sbjct: 1165FHSSTKTVHDVCWSPRSSTVFACVHEGAVEVWDL-AQSTLDAVITITPTSGAKLTSVTF 1338
>34005
          Length = 456

 Score = 36.2 bits (82), Expect = 0.022,   Method: Compositional matrix adjust.
 Identities = 28/106 (26%), Positives = 46/106 (43%), Gaps = 6/106 (5%)
 Frame = +1

Query: 190 LAVSPDYKLFISGACDASAKLWDVREG---TCRQTFTGHESDINAICFFPNGE---AICT 243
           L+ SPD     SG+ D S  +WD   G       T T H++ + A+ + P      A   
Sbjct: 130 LSWSPDATFLASGSNDNSVNIWDSTLGMDVPPLHTLTSHQAAVKAVAWCPWQTRMLATGG 309

Query: 244 GSDDASCRLFDLRADQELTAYSQESIICGITSVAFSLSGRLLFAGY 289
           G++D   R ++      + A   +S +C   SV +    R L +G+
Sbjct: 310 GTNDRHIRFWNTNTGACVKAVDTQSQVC---SVLWCKEHRELVSGH 438
>03044
          Length = 1952

 Score = 35.8 bits (81), Expect = 0.024,   Method: Compositional matrix adjust.
 Identities = 58/250 (23%), Positives = 93/250 (37%), Gaps = 4/250 (1%)
 Frame = -2

Query: 50   TLRGHLAKIYAMHWATDSKLLVSASQDGKLIVWDTYTTNK--VHAIPLRSSWVMTCA-YA 106
            TL  H  ++  + WA  S  +V+   D    VW TY   K   H + LR +   TC  ++
Sbjct: 1669 TLGEHGQRVTGIDWAPKSNRIVTCGADRNAYVW-TYQDGKWQPHLVILRINRAATCVKWS 1493

Query: 107  PSGNFVACGGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFLDDNNIVTSSGDTTC 166
            P  N  A G    + S+ +    E    VS+ +         C     NNI+ ++G T  
Sbjct: 1492 PEENKFAVGSSARLISV-SYYEEEHRWWVSKHIKKPIRSTVTCLDWHPNNILIAAGSTDF 1316

Query: 167  ALWDIETGQQKTVFVGHTGDCMSLAVSPDYKLFISGACDASAKLWDVREGTCRQTFTGHE 226
                     +  VF G+  +  +            G     +K+         +   G  
Sbjct: 1315 ---------KARVFSGYVKETEAKP----------GPNSWGSKM--TFAALMAEFSNGGG 1199

Query: 227  SDINAICFFPNGEAICTGSDDASCRLFDLRADQELTAYSQESI-ICGITSVAFSLSGRLL 285
              ++A+ F P+GE I   + D+S  + D      L       +   GIT V+      ++
Sbjct: 1198 GWVHAVSFSPSGEKIAWVAHDSSVSVGDSTMQNRLVVIKDTFLPFMGITWVS---ENSMV 1028

Query: 286  FAGYDDFNCN 295
             AGYD   CN
Sbjct: 1027 AAGYD---CN 1007
>35607
          Length = 475

 Score = 35.8 bits (81), Expect = 0.028,   Method: Compositional matrix adjust.
 Identities = 31/140 (22%), Positives = 57/140 (40%)
 Frame = +2

Query: 194 PDYKLFISGACDASAKLWDVREGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLF 253
           PD     +G  D + + WD+REG   Q      S I ++ + P G+ +  G + ++  + 
Sbjct: 8   PDGTKLWTGGLDNTVRSWDLREGRQLQQHD-FSSQIFSLGYCPTGDWLAVGMESSNVEVL 184

Query: 254 DLRADQELTAYSQESIICGITSVAFSLSGRLLFAGYDDFNCNVWDSLKCERVGILSGHDN 313
                 +   +  ES +    S+ F+  G+   +   D   N W +     +       +
Sbjct: 185 HHSKPDKYQLHLHESCVL---SLKFAYCGKWFVSTGKDNLLNAWRTPYGASIFQSKESSS 355

Query: 314 RVSCLGVTADGMAVATGSWD 333
            +SC  + AD   + TGS D
Sbjct: 356 VLSC-DIAADDKYIVTGSGD 412

 Score = 31.2 bits (69), Expect = 0.59,   Method: Compositional matrix adjust.
 Identities = 31/129 (24%), Positives = 58/129 (44%), Gaps = 2/129 (1%)
 Frame = +2

Query: 45  MRTRRTLRGH--LAKIYAMHWATDSKLLVSASQDGKLIVWDTYTTNKVHAIPLRSSWVMT 102
           +R  R L+ H   ++I+++ +      L    +   + V      +K + + L  S V++
Sbjct: 65  LREGRQLQQHDFSSQIFSLGYCPTGDWLAVGMESSNVEVLHHSKPDK-YQLHLHESCVLS 241

Query: 103 CAYAPSGNFVACGGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFLDDNNIVTSSG 162
             +A  G +    G DN+ + +       ++  S+E S+    LSC    DD  IVT SG
Sbjct: 242 LKFAYCGKWFVSTGKDNLLNAWR-TPYGASIFQSKESSS---VLSCDIAADDKYIVTGSG 409

Query: 163 DTTCALWDI 171
           D    L+++
Sbjct: 410 DKKATLYEV 436

 Score = 29.6 bits (65), Expect = 1.9,   Method: Compositional matrix adjust.
 Identities = 27/104 (25%), Positives = 43/104 (41%)
 Frame = +2

Query: 236 PNGEAICTGSDDASCRLFDLRADQELTAYSQESIICGITSVAFSLSGRLLFAGYDDFNCN 295
           P+G  + TG  D + R +DLR  ++L    Q      I S+ +  +G  L  G +  N  
Sbjct: 8   PDGTKLWTGGLDNTVRSWDLREGRQL---QQHDFSSQIFSLGYCPTGDWLAVGMESSNVE 178

Query: 296 VWDSLKCERVGILSGHDNRVSCLGVTADGMAVATGSWDSFLKIW 339
           V    K ++   L  H++ V  L     G    +   D+ L  W
Sbjct: 179 VLHHSKPDKYQ-LHLHESCVLSLKFAYCGKWFVSTGKDNLLNAW 307
>31384
          Length = 474

 Score = 35.8 bits (81), Expect = 0.029,   Method: Compositional matrix adjust.
 Identities = 21/81 (25%), Positives = 37/81 (45%), Gaps = 6/81 (7%)
 Frame = -1

Query: 146 LSCCRF----LDDNNIVTSSGDTTCALWDIETGQQ--KTVFVGHTGDCMSLAVSPDYKLF 199
           +SC +F    L    +++ S D   + W+++   Q        HTG  + +  S D    
Sbjct: 267 VSCLKFSPGALPSTFLISGSWDNKVSCWEVQQSGQTIPKAQQTHTGPVLDVDWSDDGTKV 88

Query: 200 ISGACDASAKLWDVREGTCRQ 220
            + +CD +AK+WD+    C Q
Sbjct: 87  FTASCDKTAKVWDLNSNQCMQ 25
>33180
          Length = 460

 Score = 35.4 bits (80), Expect = 0.030,   Method: Compositional matrix adjust.
 Identities = 27/104 (25%), Positives = 52/104 (50%), Gaps = 9/104 (8%)
 Frame = -2

Query: 229 INAICFFPNGEAICTGSDDASCRLFDLRADQ---ELTAYSQESIICGITSVAFSL-SGRL 284
           I ++ F  +   I  G++D    ++D  ++Q   ++ A+  +     + +VAF+  S ++
Sbjct: 444 IFSLMFSSDNTEIVGGANDGCLYVYDRESNQRTLKIDAHDDD-----VNAVAFADDSSQI 280

Query: 285 LFAGYDDFNCNVWDSLKCER-----VGILSGHDNRVSCLGVTAD 323
           L++G DD  C VWD           VGI++GH + V+ +    D
Sbjct: 279 LYSGGDDGLCKVWDRRTLREDNPLPVGIMAGHSDGVTYIDTKGD 148
>29912
          Length = 510

 Score = 33.9 bits (76), Expect = 0.095,   Method: Compositional matrix adjust.
 Identities = 32/146 (21%), Positives = 61/146 (41%), Gaps = 8/146 (5%)
 Frame = +3

Query: 99  WVMTCAYAPSGNFVACGGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFLDDNNIV 158
           ++   ++   GN++A G       ++++  +       ++L    G+ +    L  N+ +
Sbjct: 15  YIGAVSWIKEGNYLALGTSTGEVQVWDVTQQ-------KKLRTMAGHAARVGSLSWNSFI 173

Query: 159 TSSGDTTCALW--DIETGQQKT-VFVGHTGDCMSLAVSPDYKLFISGACDASAKLW--DV 213
            SSG  +  +   D+           GH+ +   L  SPD K   SGA D    +W   V
Sbjct: 174 VSSGSRSGNIHHHDVRVADHHVGTLSGHSQEVCGLRWSPDGKYLASGANDNLLCVWPAQV 353

Query: 214 REGTCRQ---TFTGHESDINAICFFP 236
             G   Q   TF+ H++ + A+ + P
Sbjct: 354 TGGNSTQPLHTFSQHQAAVKALAWCP 431

 Score = 33.5 bits (75), Expect = 0.11,   Method: Compositional matrix adjust.
 Identities = 26/88 (29%), Positives = 35/88 (39%), Gaps = 11/88 (12%)
 Frame = +3

Query: 42  RVQMRTRRTLRGHLAKIYAMHWATDSKLLVSASQDGKLIVWDTYTTNKVHAIPLRS---- 97
           RV      TL GH  ++  + W+ D K L S + D  L VW    T      PL +    
Sbjct: 219 RVADHHVGTLSGHSQEVCGLRWSPDGKYLASGANDNLLCVWPAQVTGGNSTQPLHTFSQH 398

Query: 98  -------SWVMTCAYAPSGNFVACGGLD 118
                  +W   C + PS   +A GG D
Sbjct: 399 QAAVKALAW---CPWQPS--XLASGGGD 467

 Score = 32.3 bits (72), Expect = 0.27,   Method: Compositional matrix adjust.
 Identities = 29/134 (21%), Positives = 59/134 (44%), Gaps = 11/134 (8%)
 Frame = +3

Query: 145 YLSCCRFLDDNNIV---TSSGDTTCALWDIETGQQKTVFVGHTGDCMSLAVSPDYKLFI- 200
           Y+    ++ + N +   TS+G+    +WD+   ++     GH     SL+    +  FI 
Sbjct: 15  YIGAVSWIKEGNYLALGTSTGEVQ--VWDVTQQKKLRTMAGHAARVGSLS----WNSFIV 176

Query: 201 -SGACDASAKLWDVREGTCR-QTFTGHESDINAICFFPNGEAICTGSDDA-----SCRLF 253
            SG+   +    DVR       T +GH  ++  + + P+G+ + +G++D        ++ 
Sbjct: 177 SSGSRSGNIHHHDVRVADHHVGTLSGHSQEVCGLRWSPDGKYLASGANDNLLCVWPAQVT 356

Query: 254 DLRADQELTAYSQE 267
              + Q L  +SQ 
Sbjct: 357 GGNSTQPLHTFSQH 398
>15972
          Length = 1069

 Score = 32.3 bits (72), Expect = 0.26,   Method: Compositional matrix adjust.
 Identities = 16/51 (31%), Positives = 24/51 (47%)
 Frame = +3

Query: 166 CALWDIETGQQKTVFVGHTGDCMSLAVSPDYKLFISGACDASAKLWDVREG 216
           C   +   G  +  F GH G    LAV P  KL ++ + D + +LW+   G
Sbjct: 183 CVCGECPPG*PERTFSGHKGPVRHLAVHPSGKLTLTVSQDRTLRLWNNMNG 335

 Score = 29.6 bits (65), Expect = 1.8,   Method: Compositional matrix adjust.
 Identities = 15/56 (26%), Positives = 27/56 (48%), Gaps = 5/56 (8%)
 Frame = +3

Query: 204 CDASAKLWDVREGTC-----RQTFTGHESDINAICFFPNGEAICTGSDDASCRLFD 254
           C A  ++     G C      +TF+GH+  +  +   P+G+   T S D + RL++
Sbjct: 156 CSAPVRMGPCVCGECPPG*PERTFSGHKGPVRHLAVHPSGKLTLTVSQDRTLRLWN 323
>19140
          Length = 573

 Score = 32.0 bits (71), Expect = 0.40,   Method: Compositional matrix adjust.
 Identities = 15/51 (29%), Positives = 28/51 (54%)
 Frame = -3

Query: 182 GHTGDCMSLAVSPDYKLFISGACDASAKLWDVREGTCRQTFTGHESDINAI 232
           GHT +  +L ++ D    +SG+ D + +LW + +  C  TF  H+  + A+
Sbjct: 493 GHTDNVKALVLNRDGTQCLSGSSDGTIRLWSLGQQRCVATFRVHDEGVWAL 341

 Score = 28.9 bits (63), Expect = 3.2,   Method: Compositional matrix adjust.
 Identities = 12/38 (31%), Positives = 20/38 (52%)
 Frame = -3

Query: 302 CERVGILSGHDNRVSCLGVTADGMAVATGSWDSFLKIW 339
           C ++  L GH + V  L +  DG    +GS D  +++W
Sbjct: 517 CHKLMKLKGHTDNVKALVLNRDGTQCLSGSSDGTIRLW 404
>20662
          Length = 1220

 Score = 31.6 bits (70), Expect = 0.49,   Method: Compositional matrix adjust.
 Identities = 21/67 (31%), Positives = 34/67 (50%), Gaps = 3/67 (4%)
 Frame = +2

Query: 64  ATDSKLLVSASQDGKLIVWDTYTTNKVHAIPLRSS-WVMTCA-YAPSG-NFVACGGLDNM 120
            T+  L +S SQDGK+++WD   +     +P  SS +  TC  + P+  N  A G     
Sbjct: 539 PTEPALFLSCSQDGKIVLWDVRESKPATCLPKCSSGFKPTCVQWQPNARNMYAVGDEGGH 718

Query: 121 CSIYNLK 127
            S+ +L+
Sbjct: 719 VSVQDLR 739
>04088
          Length = 511

 Score = 31.6 bits (70), Expect = 0.50,   Method: Compositional matrix adjust.
 Identities = 19/67 (28%), Positives = 29/67 (43%), Gaps = 2/67 (2%)
 Frame = +3

Query: 158 VTSSGDTTCALWDIETGQQKTVFVGHTGDCMSLA--VSPDYKLFISGACDASAKLWDVRE 215
           + SS D T  L D +TG+    F GH      +   ++ +  L +SG+ D     WD+ E
Sbjct: 78  LVSSQDNTVRLMDKDTGEMLNEFTGHKHSQYKIDSCLNNEDTLVVSGSEDGKVYFWDLVE 257

Query: 216 GTCRQTF 222
                T 
Sbjct: 258 AKLVDTL 278
>31054
          Length = 392

 Score = 31.2 bits (69), Expect = 0.58,   Method: Compositional matrix adjust.
 Identities = 17/58 (29%), Positives = 29/58 (50%)
 Frame = -2

Query: 199 FISGACDASAKLWDVREGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLR 256
           F  G+ D   K W   +G   Q  +GH + IN +    +G  + +G+D+ +  L+D R
Sbjct: 367 FAXGSPDX-VKQWKFPDGNFIQNLSGHNAIINTLAVNSDG-VLVSGADNGTMHLWDWR 200

 Score = 29.3 bits (64), Expect = 2.5,   Method: Compositional matrix adjust.
 Identities = 27/99 (27%), Positives = 40/99 (40%)
 Frame = -2

Query: 169 WDIETGQQKTVFVGHTGDCMSLAVSPDYKLFISGACDASAKLWDVREGTCRQTFTGHESD 228
           W    G       GH     +LAV+ D  + +SGA + +  LWD R G   Q    H + 
Sbjct: 334 WKFPDGNFIQNLSGHNAIINTLAVNSD-GVLVSGADNGTMHLWDWRTGYNFQRI--HAAV 164

Query: 229 INAICFFPNGEAICTGSDDASCRLFDLRADQELTAYSQE 267
                   +G   CT  D +  RL    AD+ +  Y ++
Sbjct: 163 QPGSLDSESGFFACT-FDQSESRLITAEADKTIKVYRED 50
>11915
          Length = 737

 Score = 30.8 bits (68), Expect = 0.72,   Method: Compositional matrix adjust.
 Identities = 30/113 (26%), Positives = 50/113 (44%), Gaps = 18/113 (15%)
 Frame = +1

Query: 22  RKACADITLAELVSGLEVVGRVQMRTRRT------LRGHLAKIYAMHWATDSKL-LVSAS 74
           R+   D +   L +G  V GR+++    T      +  H A ++ +H+A D+ L L+SAS
Sbjct: 418 RQQQNDSSTLVLATG-HVSGRIKLWNCETGKLLIEMMDHKATVHDLHFAADNSLCLMSAS 594

Query: 75  QDGKLIVWD-----------TYTTNKVHAIPLRSSWVMTCAYAPSGNFVACGG 116
            DG + +W+           T  TN  HA         +C ++    +VA  G
Sbjct: 595 HDGTVKLWEFDDQGDCNMYLTLRTNAKHAF--------SCRWSHDRRYVATAG 729
>12140
          Length = 727

 Score = 30.4 bits (67), Expect = 0.98,   Method: Compositional matrix adjust.
 Identities = 19/70 (27%), Positives = 32/70 (45%), Gaps = 5/70 (7%)
 Frame = +2

Query: 222 FTGHESDINAICFFPN--GEAICTGSDDASCRLFDLRADQELTAY---SQESIICGITSV 276
           ++ H+S +N++CF P+  G  +  GS D S  +     D    +    +  +I C   S 
Sbjct: 26  YSNHDSSVNSVCFAPHELGLILACGSSDGSLSIISTTGDGNWDSKKINNAHTIGCNAVSW 205

Query: 277 AFSLSGRLLF 286
           A S +   LF
Sbjct: 206 APSTAPNALF 235

 Score = 27.3 bits (59), Expect = 8.0,   Method: Compositional matrix adjust.
 Identities = 48/209 (22%), Positives = 77/209 (36%), Gaps = 11/209 (5%)
 Frame = +2

Query: 100 VMTCAYAPS--GNFVACGGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFLDDNNI 157
           V +  +AP   G  +ACG  D   SI +  + +GN    +  +AHT  + C      N +
Sbjct: 47  VNSVCFAPHELGLILACGSSDGSLSIIST-TGDGNWDSKKINNAHT--IGC------NAV 199

Query: 158 VTSSGDTTCALWDIETGQQKTVFVGHTGDCMSLAVSPDYKLFISGACDASAKLW--DVRE 215
             +      AL+D    QQ                    K F+SG CD   K+W  D   
Sbjct: 200 SWAPSTAPNALFDQSARQQPV------------------KRFVSGGCDNLVKIWREDETG 325

Query: 216 GTCRQTFTGHESDINAICFFPN----GEAICTGSDDASCRLFDLRAD---QELTAYSQES 268
               Q   GH   +  + + P+       I + S D  CR+     D    + T+     
Sbjct: 326 WVEDQKLEGHSDWVRDVAWAPSIGLPRNVIASCSQD--CRVIIWTNDGSSNQWTSRILNK 499

Query: 269 IICGITSVAFSLSGRLLFAGYDDFNCNVW 297
               +  V++S++G +L     D    +W
Sbjct: 500 FSDVVWHVSWSVTGNILAVSGGDNKVTLW 586
>07781
          Length = 1269

 Score = 30.4 bits (67), Expect = 0.99,   Method: Compositional matrix adjust.
 Identities = 28/94 (29%), Positives = 43/94 (45%), Gaps = 4/94 (4%)
 Frame = -2

Query: 210 LWDVREGTCRQTFTGHESDINA-ICFFP--NGEAICTGSDDASCRLFDLRADQELTAYSQ 266
           +++V   T R+T      D  A IC F   N E I +GSDD   +++DLR        + 
Sbjct: 848 VFEVESTTVRETSQWRAHDFEAWICAFDQWNTELIYSGSDDCKLKVWDLRVGT-TPVLTN 672

Query: 267 ESIICGITSV-AFSLSGRLLFAGYDDFNCNVWDS 299
                G+TS+ +      LL  G  D N  ++D+
Sbjct: 671 SRFTMGVTSIQSCPQREHLLAVGSYDENLRLFDT 570
>16105
          Length = 960

 Score = 30.4 bits (67), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 46/172 (26%), Positives = 63/172 (36%), Gaps = 13/172 (7%)
 Frame = -2

Query: 96  RSSWVMT-CAYAPSGNFVACGGLDNMCSIYNLKSREGNVKVSRELSA-HTGYLSCCRFL- 152
           R+SW  T CA  P    V          +    SR G V V   L A H G +   ++  
Sbjct: 722 RTSWESTYCAVNPKFVAVMTEAAGGGAFLVLPLSRVGRVPVDNPLVAGHKGAVLDIQWCP 543

Query: 153 -DDNNIVTSSGDTTCALWDIE-----TGQQKTV--FVGHTGDCMSLAVSPDYK-LFISGA 203
            +DN I ++S D T  +W I      T     V   VGH   C  +   P  + + +S  
Sbjct: 542 HNDNVIASASDDCTVKVWQIPDSGLVTNLTDPVVDLVGHQKRCCLIVWHPSAQNVLVSAG 363

Query: 204 CDASAKLWDVREGTCRQTFTGHESD-INAICFFPNGEAICTGSDDASCRLFD 254
            D     W+V  GT          D I  + F  NG  +     D   R+ D
Sbjct: 362 ADNKILFWNV--GTGEPMLEVDVPDMIYCMSFNFNGSRLVCTCKDKKLRIID 213
>00345
          Length = 2923

 Score = 30.0 bits (66), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 20/53 (37%), Positives = 23/53 (43%)
 Frame = -3

Query: 237  NGEAICTGSDDASCRLFDLRADQELTAYSQESIICGITSVAFSLSGRLLFAGY 289
             G AICT  D  + RL  L     L A      IC    V +SL+  L F GY
Sbjct: 2735 RGAAICTAPDLTAFRLSPLPYRPLLLAC*HFIFICHCICVLYSLAVFLSFFGY 2577
>18320
          Length = 450

 Score = 30.0 bits (66), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 22/81 (27%), Positives = 36/81 (44%), Gaps = 9/81 (11%)
 Frame = -2

Query: 269 IICGITSVAFSLSGRLLFAGYDDFNCNVWDSLKCERVGILSGHDNRVSCLGVTADG---- 324
           +   +  V    +G+LL AG  D    + D  K +     S  D ++ C+     G    
Sbjct: 287 LFAAVDVVHLMQNGQLLAAGSRDRYLTLLDLTKYDPARPKSKKDMQLHCIDKAHSGWIWC 108

Query: 325 MA-----VATGSWDSFLKIWN 340
           MA     + TGSWD+ +K+W+
Sbjct: 107 MASLNQHLYTGSWDTKIKVWD 45
>22113
          Length = 614

 Score = 30.0 bits (66), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 22/81 (27%), Positives = 39/81 (48%)
 Frame = +3

Query: 91  HAIPLRSSWVMTCAYAPSGNFVACGGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCR 150
           + + L  S V++  +A  G +    G DN+ + +       ++  S+E S+    LSC  
Sbjct: 84  YQLHLHESCVLSLRFATCGKWFVSTGKDNLLNAWR-TPYGASIFQSKETSS---VLSCDI 251

Query: 151 FLDDNNIVTSSGDTTCALWDI 171
             DD  IVT SGD    ++++
Sbjct: 252 STDDKYIVTGSGDKKATVYEV 314
>27270
          Length = 1078

 Score = 29.3 bits (64), Expect = 2.6,   Method: Compositional matrix adjust.
 Identities = 15/42 (35%), Positives = 22/42 (52%)
 Frame = +2

Query: 52  RGHLAKIYAMHWATDSKLLVSASQDGKLIVWDTYTTNKVHAI 93
           +GH   +  M W  D + L S+S DG +I W+    N +H I
Sbjct: 263 KGHSKAVTDMCWRADGRTLYSSSLDGHVIGWN---VNTLHMI 379

 Score = 28.9 bits (63), Expect = 2.9,   Method: Compositional matrix adjust.
 Identities = 14/55 (25%), Positives = 26/55 (47%), Gaps = 2/55 (3%)
 Frame = +2

Query: 205 DASAKLWDVREGTCRQTFTGHESDINAI--CFFPNGEAICTGSDDASCRLFDLRA 257
           D + K+WD+      Q F+GH +++  +     P+ E    G  + +C +F   A
Sbjct: 461 DHTIKMWDLTTKNVLQEFSGHSTEVIKLLPVLKPSSEQNDIGDSNLACYVFSAAA 625
>15337
          Length = 860

 Score = 28.9 bits (63), Expect = 3.0,   Method: Compositional matrix adjust.
 Identities = 16/69 (23%), Positives = 28/69 (40%)
 Frame = -1

Query: 37  LEVVGRVQMRTRRTLRGHLAKIYAMHWATDSKLLVSASQDGKLIVWDTYTTNKVHAIPLR 96
           L V     M    T++ +   +  + W+ D K +V+  +D  + VW  +    V      
Sbjct: 257 LRVFNYNSMELIGTMKSYFGGLLCVCWSPDGKYIVTGGEDDLVTVWSFHEKRVVCRGHGH 78

Query: 97  SSWVMTCAY 105
            SWV   A+
Sbjct: 77  KSWVNVVAF 51

 Score = 28.9 bits (63), Expect = 3.1,   Method: Compositional matrix adjust.
 Identities = 12/63 (19%), Positives = 31/63 (49%)
 Frame = -1

Query: 67  SKLLVSASQDGKLIVWDTYTTNKVHAIPLRSSWVMTCAYAPSGNFVACGGLDNMCSIYNL 126
           S+ L    QDG L V++  +   +  +      ++   ++P G ++  GG D++ ++++ 
Sbjct: 293 SRYLAVVGQDGHLRVFNYNSMELIGTMKSYFGGLLCVCWSPDGKYIVTGGEDDLVTVWSF 114

Query: 127 KSR 129
             +
Sbjct: 113 HEK 105
>22154
          Length = 382

 Score = 28.9 bits (63), Expect = 3.2,   Method: Compositional matrix adjust.
 Identities = 24/91 (26%), Positives = 44/91 (48%), Gaps = 9/91 (9%)
 Frame = -2

Query: 109 GNFVACGGLDNMCSIYNLKSREGNV-KVSRELSAHTGYLSCCRFLDDNNIVTSSGD---T 164
           G+FV  G L    S+   K REG + +++R+   +  +++    LDD+N + +       
Sbjct: 318 GDFVLVGDLMRSVSLLAYKQREGQLEEIARD--CNPNWMTSVEILDDDNFLGAENSFNLF 145

Query: 165 TC-----ALWDIETGQQKTVFVGHTGDCMSL 190
           TC     A  D E  Q + V + H G+ +++
Sbjct: 144 TCQKDSAAATDEERSQMQEVGLFHYGEFVNV 52
>12076
          Length = 949

 Score = 28.9 bits (63), Expect = 3.3,   Method: Compositional matrix adjust.
 Identities = 11/27 (40%), Positives = 17/27 (62%)
 Frame = -1

Query: 241 ICTGSDDASCRLFDLRADQELTAYSQE 267
           IC  SDDASCR + L+ +  +  Y ++
Sbjct: 295 ICHTSDDASCRFYTLKENTAVQVYDRQ 215
>27525
          Length = 828

 Score = 28.1 bits (61), Expect = 5.3,   Method: Compositional matrix adjust.
 Identities = 12/40 (30%), Positives = 20/40 (50%)
 Frame = +2

Query: 219 RQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRAD 258
           R +F   ++ INAI F P+G  +  G  D    ++ +  D
Sbjct: 47  RNSFQVGQAQINAISFSPDGSQLAVGCHDGFVHVYVVHED 166
>17298
          Length = 476

 Score = 27.7 bits (60), Expect = 6.6,   Method: Compositional matrix adjust.
 Identities = 17/84 (20%), Positives = 34/84 (40%)
 Frame = -1

Query: 170 DIETGQQKTVFVGHTGDCMSLAVSPDYKLFISGACDASAKLWDVREGTCRQTFTGHESDI 229
           ++ +GQ    +  H G    +  + +  + +SG+ D + + WD R  +        E+  
Sbjct: 254 NVASGQALRKYRDHAGTVNCVKFNEESTVILSGSLDNTVRAWDTRSRSHTPIQVLDEATD 75

Query: 230 NAICFFPNGEAICTGSDDASCRLF 253
           +      +   I TGS D   R +
Sbjct: 74  SVTSIQVSDYEILTGSADGRVRRY 3
>25930
          Length = 419

 Score = 27.7 bits (60), Expect = 7.6,   Method: Compositional matrix adjust.
 Identities = 12/31 (38%), Positives = 18/31 (58%)
 Frame = +1

Query: 53  GHLAKIYAMHWATDSKLLVSASQDGKLIVWD 83
           G    I  ++W+ D+  L+S S+ G L VWD
Sbjct: 190 GQDDSIKNLNWSLDATRLISVSESGTLQVWD 282
>13983
          Length = 464

 Score = 27.3 bits (59), Expect = 9.7,   Method: Compositional matrix adjust.
 Identities = 13/26 (50%), Positives = 18/26 (69%)
 Frame = -3

Query: 66  DSKLLVSASQDGKLIVWDTYTTNKVH 91
           ++K LV A ++G L VWD+Y  N VH
Sbjct: 390 NAKSLV-AVKNGDLFVWDSYNANVVH 316
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|13928670|ref|NP_075373.1| vacuolar protein sorting 35
[Mus musculus]
         (796 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

37525                                                                 208   5e-78
26103                                                                 186   5e-47
>37525
          Length = 699

 Score =  208 bits (530), Expect(3) = 5e-78,   Method: Compositional matrix adjust.
 Identities = 99/156 (63%), Positives = 122/156 (78%)
 Frame = -2

Query: 640 CFSEENHEPLRTQCALAASKLLKKPDQGRAVSTCAHLFWSGRNTDKNGEELHGGKRVMEC 699
           CF EENHEPL+T CA AASKLLKKPDQ R VS C+HLFWSG+    +  E+   KR  +C
Sbjct: 479 CFGEENHEPLKTHCAQAASKLLKKPDQCRGVSVCSHLFWSGK-IGIDETEMRDAKRTTDC 303

Query: 700 LKKALKIANQCMDPSLQVQLFIEILNRYIYFYEKENDAVTIQVLNQLIQKIREDLPNLES 759
           LKK +KIANQCMD S+QVQLF+E+LN YIYFYEK  + + IQVLNQ+I ++RE LPNLE+
Sbjct: 302 LKKGVKIANQCMDSSVQVQLFVEVLNHYIYFYEKNCEQIAIQVLNQIIARVRELLPNLEA 123

Query: 760 SEETEQINKHFHNTLEHLRSRRESPESEGPIYEGLI 795
           + ETEQINKHF NTLEHL+ + E+ +S+   YEGL+
Sbjct: 122 NXETEQINKHFKNTLEHLQLKMEASDSKVS-YEGLV 18

 Score = 72.4 bits (176), Expect(3) = 5e-78,   Method: Compositional matrix adjust.
 Identities = 34/47 (72%), Positives = 38/47 (80%)
 Frame = -3

Query: 602 VAYEFMSQAFSLYEDEISDSKAQLAAITLIIGTFERMKCFSEENHEP 648
           VAYEF SQAFSLYEDEISDSKAQLAAITL+IGT E+M    ++   P
Sbjct: 592 VAYEFFSQAFSLYEDEISDSKAQLAAITLMIGTLEQMSVLGKKTMSP 452

 Score = 51.2 bits (121), Expect(3) = 5e-78,   Method: Composition-based stats.
 Identities = 27/37 (72%), Positives = 30/37 (81%)
 Frame = -1

Query: 565 HQTISALIKAELAELPLRLFLQGALAAGEIGFENHET 601
           HQTI    +AE AE+PLRLFLQGALAAG+I FEN ET
Sbjct: 699 HQTIGP-DQAEQAEIPLRLFLQGALAAGKIRFENSET 592
>26103
          Length = 441

 Score =  186 bits (471), Expect = 5e-47,   Method: Compositional matrix adjust.
 Identities = 85/143 (59%), Positives = 111/143 (77%)
 Frame = -1

Query: 644 ENHEPLRTQCALAASKLLKKPDQGRAVSTCAHLFWSGRNTDKNGEELHGGKRVMECLKKA 703
           EN EPLRT CALAASKLLKKPDQ R V  CA LFWSG+   +NGEE+   KR ++CLKK 
Sbjct: 441 ENAEPLRTNCALAASKLLKKPDQCRGVVACAALFWSGK---QNGEEMRDEKRTLDCLKKG 271

Query: 704 LKIANQCMDPSLQVQLFIEILNRYIYFYEKENDAVTIQVLNQLIQKIREDLPNLESSEET 763
            +IA+QC+D  +QVQL++E+LN Y++++E+ N  +T+ +LNQLI K+ E+LPNLE SEET
Sbjct: 270 ARIASQCLDTGVQVQLYVELLNHYLFYFERGNSLITVAMLNQLIAKVNEELPNLEPSEET 91

Query: 764 EQINKHFHNTLEHLRSRRESPES 786
           +QI  H+ NTL HLRSR ES ++
Sbjct: 90  KQIESHYKNTLAHLRSRIESTDT 22
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|13937391|ref|NP_034442.1| guanine nucleotide-binding
protein, beta-2 subunit [Mus musculus]
         (340 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

30295                                                                 285   1e-77
17266                                                                 264   3e-71
14555                                                                  95   4e-34
17598                                                                  94   1e-19
34511                                                                  75   2e-16
13335                                                                  81   5e-16
02147                                                                  78   5e-15
30256                                                                  77   1e-14
12806                                                                  77   1e-14
00561                                                                  74   6e-14
27465                                                                  73   2e-13
02960                                                                  66   2e-11
19949                                                                  66   2e-11
17602                                                                  65   5e-11
03395                                                                  59   2e-09
01805                                                                  59   3e-09
02090                                                                  58   7e-09
26107                                                                  55   6e-08
03156                                                                  55   6e-08
01327                                                                  54   8e-08
21105                                                                  54   1e-07
01249                                                                  53   2e-07
37180                                                                  50   2e-06
03387                                                                  49   3e-06
14500                                                                  42   3e-06
12574                                                                  49   3e-06
10162                                                                  49   4e-06
19498                                                                  49   4e-06
16199                                                                  39   3e-05
13278                                                                  45   4e-05
31384                                                                  44   7e-05
29912                                                                  44   1e-04
01462                                                                  43   2e-04
19863                                                                  43   2e-04
11493                                                                  43   2e-04
01598                                                                  43   2e-04
12960                                                                  43   2e-04
18981                                                                  43   2e-04
21921                                                                  40   0.001
10264                                                                  40   0.002
33180                                                                  40   0.002
15118                                                                  39   0.003
19140                                                                  38   0.006
34005                                                                  37   0.010
27806                                                                  37   0.013
35607                                                                  35   0.031
18320                                                                  35   0.047
17298                                                                  35   0.057
22114                                                                  34   0.071
31474                                                                  34   0.090
11915                                                                  33   0.15 
27270                                                                  33   0.20 
03734                                                                  32   0.26 
26939                                                                  32   0.27 
15745                                                                  32   0.30 
31864                                                                  32   0.32 
15972                                                                  32   0.37 
15337                                                                  32   0.39 
04358                                                                  32   0.47 
07665                                                                  32   0.48 
04088                                                                  31   0.58 
31054                                                                  31   0.84 
12140                                                                  31   0.90 
20662                                                                  30   1.1  
17807                                                                  30   1.8  
04524                                                                  30   2.0  
22113                                                                  29   3.3  
15780                                                                  28   5.0  
16105                                                                  28   7.0  
38177                                                                  28   7.1  
00825                                                                  27   8.6  
>30295
          Length = 593

 Score =  285 bits (730), Expect = 1e-77,   Method: Compositional matrix adjust.
 Identities = 135/153 (88%), Positives = 141/153 (92%)
 Frame = +2

Query: 18  IRDARKACGDSTLTQITAGLDPVGRIQMRTRRTLRGHLAKIYAMHWGTDSRLLVSASQDG 77
           IR+ARKA GD+TL Q TA  D VGRIQMRTRRTLR HLAKIYAMHW TDSR LVSASQDG
Sbjct: 134 IREARKAAGDTTLAQATASYDSVGRIQMRTRRTLRXHLAKIYAMHWATDSRNLVSASQDG 313

Query: 78  KLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFVACGGLDNICSIYSLKTREGNVRVSR 137
           KLI+WD YTTNKVHAIPLRSSWVMTCAYAPSG +VACGGLDNICSIYSLKTREGNVRVSR
Sbjct: 314 KLIVWDGYTTNKVHAIPLRSSWVMTCAYAPSGGYVACGGLDNICSIYSLKTREGNVRVSR 493

Query: 138 ELPGHTGYLSCCRFLDDNQIITSSGDTTCALWD 170
           ELPGHTGYLSCCRF+DDNQI+TSSGD TCALWD
Sbjct: 494 ELPGHTGYLSCCRFIDDNQIVTSSGDMTCALWD 592

 Score = 33.5 bits (75), Expect = 0.11,   Method: Compositional matrix adjust.
 Identities = 32/128 (25%), Positives = 51/128 (39%), Gaps = 5/128 (3%)
 Frame = +2

Query: 132 NVRVSRELPGHTGYLSCCRFLDDNQ-IITSSGDTTCALWDIETGQQTVGFAGHSGDVMSL 190
            +R  R L  H   +    +  D++ ++++S D    +WD  T  +       S  VM+ 
Sbjct: 212 QMRTRRTLRXHLAKIYAMHWATDSRNLVSASQDGKLIVWDGYTTNKVHAIPLRSSWVMTC 391

Query: 191 SLAPDGRTFVSGACD--ASIKLWDVRDSMCR--QTFIGHESDINAVAFFPNGYAFTTGSD 246
           + AP G     G  D   SI     R+   R  +   GH   ++   F  +     T S 
Sbjct: 392 AYAPSGGYVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFIDDN-QIVTSSG 568

Query: 247 DATCRLFD 254
           D TC L+D
Sbjct: 569 DMTCALWD 592
>17266
          Length = 480

 Score =  264 bits (675), Expect(2) = 3e-71,   Method: Compositional matrix adjust.
 Identities = 125/147 (85%), Positives = 135/147 (91%)
 Frame = -1

Query: 190 LSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTTGSDDAT 249
           LSLAPD RTFVSGACDAS KLWDVRD MC+QTF GHESDINA+ +FPNG+AF TGSDDAT
Sbjct: 441 LSLAPDMRTFVSGACDASAKLWDVRDGMCKQTFSGHESDINAITYFPNGHAFATGSDDAT 262

Query: 250 CRLFDLRADQELLMYSHDNIICGITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDRAGVLA 309
           CRLFD+RADQE+ MYSHDNIICGITSVAFS+SGRLLL GYDDFNCNIWD +K +R GVLA
Sbjct: 261 CRLFDIRADQEIGMYSHDNIICGITSVAFSKSGRLLLGGYDDFNCNIWDVLKQERTGVLA 82

Query: 310 GHDNRVSCLGVTDDGMAVATGSWDSFL 336
           GHDNRVSCLGVT+DG AVATGSWDSFL
Sbjct: 81  GHDNRVSCLGVTEDGSAVATGSWDSFL 1

 Score = 22.3 bits (46), Expect(2) = 3e-71,   Method: Compositional matrix adjust.
 Identities = 8/10 (80%), Positives = 10/10 (100%)
 Frame = -3

Query: 180 FAGHSGDVMS 189
           F+GH+GDVMS
Sbjct: 472 FSGHTGDVMS 443

 Score = 42.4 bits (98), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 28/101 (27%), Positives = 47/101 (46%), Gaps = 3/101 (2%)
 Frame = -1

Query: 151 FLDDNQIITSSGDTTCALWDIETGQQTVGFAGHSG---DVMSLSLAPDGRTFVSGACDAS 207
           F + +   T S D TC L+DI   Q+ +G   H      + S++ +  GR  + G  D +
Sbjct: 306 FPNGHAFATGSDDATCRLFDIRADQE-IGMYSHDNIICGITSVAFSKSGRLLLGGYDDFN 130

Query: 208 IKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTTGSDDA 248
             +WDV          GH++ ++ +    +G A  TGS D+
Sbjct: 129 CNIWDVLKQERTGVLAGHDNRVSCLGVTEDGSAVATGSWDS 7

 Score = 29.3 bits (64), Expect = 2.4,   Method: Compositional matrix adjust.
 Identities = 15/58 (25%), Positives = 31/58 (53%)
 Frame = -1

Query: 283 RLLLAGYDDFNCNIWDAMKGDRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
           R  ++G  D +  +WD   G      +GH++ ++ +    +G A ATGS D+  ++++
Sbjct: 420 RTFVSGACDASAKLWDVRDGMCKQTFSGHESDINAITYFPNGHAFATGSDDATCRLFD 247
>14555
          Length = 627

 Score = 95.1 bits (235), Expect(2) = 4e-34,   Method: Compositional matrix adjust.
 Identities = 46/73 (63%), Positives = 55/73 (75%)
 Frame = -2

Query: 218 CRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRADQELLMYSHDNIICGITSVA 277
           C Q F GHE+DIN V F+P+G AF TGSDDATCRLFDLRAD+E+  Y  ++II G  +V 
Sbjct: 623 CVQMFEGHEADINCVRFYPSGDAFATGSDDATCRLFDLRADREVNCYRKESIIFGCNAVD 444

Query: 278 FSRSGRLLLAGYD 290
           FS SGRLL  GY+
Sbjct: 443 FSVSGRLLFGGYE 405

 Score = 67.4 bits (163), Expect(2) = 4e-34,   Method: Compositional matrix adjust.
 Identities = 28/50 (56%), Positives = 39/50 (78%)
 Frame = -3

Query: 290 DDFNCNIWDAMKGDRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIW 339
           +D+  N+WDA+KG R+ +L GHDNRVSCL ++ DG ++ TGSWD  L+IW
Sbjct: 406 NDYTVNVWDALKGMRSTILYGHDNRVSCLRISPDGTSLCTGSWDYTLRIW 257

 Score = 37.4 bits (85), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 15/51 (29%), Positives = 28/51 (54%)
 Frame = -3

Query: 161 SGDTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLW 211
           + D T  +WD   G ++    GH   V  L ++PDG +  +G+ D ++++W
Sbjct: 409 TNDYTVNVWDALKGMRSTILYGHDNRVSCLRISPDGTSLCTGSWDYTLRIW 257

 Score = 33.5 bits (75), Expect = 0.14,   Method: Compositional matrix adjust.
 Identities = 14/49 (28%), Positives = 26/49 (53%)
 Frame = -3

Query: 205 DASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLF 253
           D ++ +WD    M      GH++ ++ +   P+G +  TGS D T R++
Sbjct: 403 DYTVNVWDALKGMRSTILYGHDNRVSCLRISPDGTSLCTGSWDYTLRIW 257
>17598
          Length = 875

 Score = 93.6 bits (231), Expect = 1e-19,   Method: Compositional matrix adjust.
 Identities = 65/256 (25%), Positives = 115/256 (44%), Gaps = 14/256 (5%)
 Frame = +1

Query: 48  RRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAP 107
           RRTL+GH   +  +    DSR ++S+S D  L +WD    N        +   +  A++P
Sbjct: 100 RRTLQGHSHFVSDVSLSADSRYVLSSSWDATLRLWDIKKGNTTRRFISHTRDALAVAFSP 279

Query: 108 SGNFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQ---IITSSGDT 164
               +A GG D    I++     G  + + +   H  +++C +F  D +   ++++S D 
Sbjct: 280 DNRQIASGGRDKALKIWNT---VGECKFTVDANSHQDWVTCVKFHQDAKSPLVVSASMDK 450

Query: 165 TCALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIG 224
           T  +WD +T      F GH   + ++ LA       SG+ D  +  W++++     TF+G
Sbjct: 451 TIKVWDNQTMTLKHTFVGHKTQINAIDLALKTYYLASGSKDGIVMTWNIQNG----TFLG 618

Query: 225 H---ESDINAVAFFPNGYAFTTGSDDA--------TCRLFDLRADQELLMYSHDNIICGI 273
               + ++NAV F PN Y    G+ +           ++ D+RA      +         
Sbjct: 619 KIDCDCEVNAVKFSPNKYWLFVGTSEGIQIWDLPNQKKIKDIRASPIDAQHKSQKKSIAC 798

Query: 274 TSVAFSRSGRLLLAGY 289
           TS+A+  SG  L AG+
Sbjct: 799 TSLAWDASGHTLFAGF 846

 Score = 73.2 bits (178), Expect = 1e-13,   Method: Compositional matrix adjust.
 Identities = 59/243 (24%), Positives = 97/243 (39%), Gaps = 54/243 (22%)
 Frame = +1

Query: 110 NFVACGGLDNICSIYSLKTRE--------GNVRVSRELPGHTGYLSCCRFLDDNQ-IITS 160
            F+  GG D +  ++ L  R+        G  R  R L GH+ ++S      D++ +++S
Sbjct: 4   EFLIXGGRDKLLIVWDLVPRKDGDEDETWGGPR--RTLQGHSHFVSDVSLSADSRYVLSS 177

Query: 161 SGDTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSG------------------ 202
           S D T  LWDI+ G  T  F  H+ D ++++ +PD R   SG                  
Sbjct: 178 SWDATLRLWDIKKGNTTRRFISHTRDALAVAFSPDNRQIASGGRDKALKIWNTVGECKFT 357

Query: 203 ---------------------------ACDASIKLWDVRDSMCRQTFIGHESDINAVAFF 235
                                      + D +IK+WD +    + TF+GH++ INA+   
Sbjct: 358 VDANSHQDWVTCVKFHQDAKSPLVVSASMDKTIKVWDNQTMTLKHTFVGHKTQINAIDLA 537

Query: 236 PNGYAFTTGSDDATCRLFDLRADQELLMYSHDNIICGITSVAFSRSGRLLLAGYDDFNCN 295
              Y   +GS D     ++++    L     D   C + +V FS +   L  G  +    
Sbjct: 538 LKTYYLASGSKDGIVMTWNIQNGTFLGKIDCD---CEVNAVKFSPNKYWLFVGTSE-GIQ 705

Query: 296 IWD 298
           IWD
Sbjct: 706 IWD 714

 Score = 67.4 bits (163), Expect = 8e-12,   Method: Compositional matrix adjust.
 Identities = 42/165 (25%), Positives = 77/165 (46%), Gaps = 4/165 (2%)
 Frame = +1

Query: 180 FAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGY 239
             GHS  V  +SL+ D R  +S + DA+++LWD++     + FI H  D  AVAF P+  
Sbjct: 109 LQGHSHFVSDVSLSADSRYVLSSSWDATLRLWDIKKGNTTRRFISHTRDALAVAFSPDNR 288

Query: 240 AFTTGSDDATCRLFDLRADQELLM--YSHDNIICGITSVAFSRSGR--LLLAGYDDFNCN 295
              +G  D   ++++   + +  +   SH +    +T V F +  +  L+++   D    
Sbjct: 289 QIASGGRDKALKIWNTVGECKFTVDANSHQD---WVTCVKFHQDAKSPLVVSASMDKTIK 459

Query: 296 IWDAMKGDRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
           +WD           GH  +++ + +      +A+GS D  +  WN
Sbjct: 460 VWDNQTMTLKHTFVGHKTQINAIDLALKTYYLASGSKDGIVMTWN 594
>34511
          Length = 1037

 Score = 75.5 bits (184), Expect(2) = 2e-16,   Method: Compositional matrix adjust.
 Identities = 31/40 (77%), Positives = 39/40 (97%)
 Frame = +3

Query: 301 KGDRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
           K +R+G+LAGHDNRVSCLGVT++GM+VATGSWDSFL++WN
Sbjct: 39  KAERSGILAGHDNRVSCLGVTENGMSVATGSWDSFLRVWN 158

 Score = 27.7 bits (60), Expect(2) = 2e-16,   Method: Compositional matrix adjust.
 Identities = 10/18 (55%), Positives = 12/18 (66%)
 Frame = +2

Query: 289 YDDFNCNIWDAMKGDRAG 306
           YDDFNCN+W  M+    G
Sbjct: 2   YDDFNCNVWYTMESRALG 55
>13335
          Length = 863

 Score = 81.3 bits (199), Expect = 5e-16,   Method: Compositional matrix adjust.
 Identities = 58/216 (26%), Positives = 97/216 (44%), Gaps = 24/216 (11%)
 Frame = +1

Query: 149 CRF-LDDNQIITSSGDTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDAS 207
           C+F    + +++ S D T  +W++ T +    + GH   VM+L+ +P+G   VSG+ +  
Sbjct: 79  CKFSPSSSHLVSGSDDDTICMWEVATQKLVRSYVGHEDSVMALAYSPNGHYLVSGSPNGD 258

Query: 208 IKLWDVRDSMCRQTFI---GHESDINAVAFFPN------------GYAFTTGSDDATCRL 252
           + +WD     CR   +    H+  +    F P                  TG  D   +L
Sbjct: 259 LYVWDASFGHCRHLTLRVDAHDLGVTCCEFSPTFGTACAENSSTCNLLLATGGKDNLIKL 438

Query: 253 FDLRAD---QELLMYSHDNIICG----ITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDRA 305
           +   A     E+ +   D I+ G    + + AFS S  LL +G  D +  +WD++KG   
Sbjct: 439 WTFSAQVGSPEVTLQCRD-ILSGHSDLVMACAFSPSSALLASGSFDKSVRLWDSVKGVAL 615

Query: 306 -GVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
             + A H   V+C   + DG  +A+GS D  +KIW 
Sbjct: 616 FSIEACHSRFVTCCAFSIDGTLLASGSMDRIIKIWK 723

 Score = 58.9 bits (141), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 51/192 (26%), Positives = 85/192 (44%), Gaps = 24/192 (12%)
 Frame = +1

Query: 49  RTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDS------YTTNKVHAIPLRSSWVMT 102
           R+  GH   + A+ +  +   LVS S +G L +WD+      + T +V A  L    V  
Sbjct: 169 RSYVGHEDSVMALAYSPNGHYLVSGSPNGDLYVWDASFGHCRHLTLRVDAHDLG---VTC 339

Query: 103 CAYAPS------------GNFVACGGLDNICSIYSLKTREGNVRVSRE----LPGHTGYL 146
           C ++P+               +A GG DN+  +++   + G+  V+ +    L GH+  +
Sbjct: 340 CEFSPTFGTACAENSSTCNLLLATGGKDNLIKLWTFSAQVGSPEVTLQCRDILSGHSDLV 519

Query: 147 SCCRFLDDNQIITS-SGDTTCALWDIETGQQTVGF-AGHSGDVMSLSLAPDGRTFVSGAC 204
             C F   + ++ S S D +  LWD   G       A HS  V   + + DG    SG+ 
Sbjct: 520 MACAFSPSSALLASGSFDKSVRLWDSVKGVALFSIEACHSRFVTCCAFSIDGTLLASGSM 699

Query: 205 DASIKLWDVRDS 216
           D  IK+W + D+
Sbjct: 700 DRIIKIWKLTDT 735

 Score = 58.9 bits (141), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 54/201 (26%), Positives = 90/201 (44%), Gaps = 28/201 (13%)
 Frame = +1

Query: 168 LWDIETGQQTVGFAGHSGDVMSL-SLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHE 226
           +WD++TG     +   S   + +   +P     VSG+ D +I +W+V      ++++GHE
Sbjct: 10  VWDVKTGSIKGEYQHASKSSIRVCKFSPSSSHLVSGSDDDTICMWEVATQKLVRSYVGHE 189

Query: 227 SDINAVAFFPNGYAFTTGSD-------DAT---CRLFDLRADQELLMYSHD-NIICGITS 275
             + A+A+ PNG+   +GS        DA+   CR   LR D      +HD  + C   S
Sbjct: 190 DSVMALAYSPNGHYLVSGSPNGDLYVWDASFGHCRHLTLRVD------AHDLGVTCCEFS 351

Query: 276 VAF-------SRSGRLLLA-GYDDFNCNIW--DAMKGDRA------GVLAGHDNRVSCLG 319
             F       S +  LLLA G  D    +W   A  G          +L+GH + V    
Sbjct: 352 PTFGTACAENSSTCNLLLATGGKDNLIKLWTFSAQVGSPEVTLQCRDILSGHSDLVMACA 531

Query: 320 VTDDGMAVATGSWDSFLKIWN 340
            +     +A+GS+D  +++W+
Sbjct: 532 FSPSSALLASGSFDKSVRLWD 594

 Score = 53.5 bits (127), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 52/223 (23%), Positives = 88/223 (39%), Gaps = 23/223 (10%)
 Frame = +1

Query: 56  AKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFVACG 115
           + I    +   S  LVS S D  + +W+  T   V +       VM  AY+P+G+++  G
Sbjct: 64  SSIRVCKFSPSSSHLVSGSDDDTICMWEVATQKLVRSYVGHEDSVMALAYSPNGHYLVSG 243

Query: 116 GLDNICSIYSLKTREGNVR-VSRELPGHTGYLSCCRFLDDNQIITSSGDTTC-------- 166
             +    +Y      G+ R ++  +  H   ++CC F        +   +TC        
Sbjct: 244 SPNG--DLYVWDASFGHCRHLTLRVDAHDLGVTCCEFSPTFGTACAENSSTCNLLLATGG 417

Query: 167 -----ALWDI--ETGQQTVG------FAGHSGDVMSLSLAPDGRTFVSGACDASIKLWD- 212
                 LW    + G   V        +GHS  VM+ + +P      SG+ D S++LWD 
Sbjct: 418 KDNLIKLWTFSAQVGSPEVTLQCRDILSGHSDLVMACAFSPSSALLASGSFDKSVRLWDS 597

Query: 213 VRDSMCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFDL 255
           V+          H   +   AF  +G    +GS D   +++ L
Sbjct: 598 VKGVALFSIEACHSRFVTCCAFSIDGTLLASGSMDRIIKIWKL 726

 Score = 41.2 bits (95), Expect = 6e-04,   Method: Compositional matrix adjust.
 Identities = 26/86 (30%), Positives = 41/86 (47%), Gaps = 1/86 (1%)
 Frame = +1

Query: 42  RIQMRTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIP-LRSSWV 100
            + ++ R  L GH   + A  +   S LL S S D  + +WDS     + +I    S +V
Sbjct: 469 EVTLQCRDILSGHSDLVMACAFSPSSALLASGSFDKSVRLWDSVKGVALFSIEACHSRFV 648

Query: 101 MTCAYAPSGNFVACGGLDNICSIYSL 126
             CA++  G  +A G +D I  I+ L
Sbjct: 649 TCCAFSIDGTLLASGSMDRIIKIWKL 726
>02147
          Length = 1547

 Score = 78.2 bits (191), Expect = 5e-15,   Method: Compositional matrix adjust.
 Identities = 56/220 (25%), Positives = 93/220 (42%), Gaps = 38/220 (17%)
 Frame = +2

Query: 159 TSSGDTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMC 218
           T + D +  +WD E G++   F+ H   V S+  + DG   ++G+ +  +K++D+ ++  
Sbjct: 224 TGAADFSAKIWDAEKGEELQTFS-HKHIVKSVDFSHDGTALLTGSNEKLLKVFDLVNTDA 400

Query: 219 R-QTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRADQELLMYSHD---------- 267
             ++F GH S+I    F  +G    + SDD T RL+ L   QE+   + D          
Sbjct: 401 EPKSFAGHTSNIKGALFLSDGKRIISASDDKTVRLWSLETCQEVQQLTFDTPPTSLTLSP 580

Query: 268 --NII-------------------------CGITSVAFSRSGRLLLAGYDDFNCNIWDAM 300
             N I                           I+S +  +S R  +AG +DF    +D  
Sbjct: 581 DKNTIIVTHSQNIAFYQADTLREMKKFEAEAPISSASLHQSERFFVAGGEDFKMYKFDYE 760

Query: 301 KGDRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
            G       GH   V C+  + DG   A+GS D  L++W 
Sbjct: 761 TGKEIESFKGHFGPVHCVRFSPDGELYASGSEDGTLRLWQ 880

 Score = 58.5 bits (140), Expect = 4e-09,   Method: Compositional matrix adjust.
 Identities = 39/164 (23%), Positives = 69/164 (42%), Gaps = 1/164 (0%)
 Frame = +2

Query: 49  RTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPS 108
           ++  GH + I    + +D + ++SAS D  + +W   T  +V  +   +    +   +P 
Sbjct: 407 KSFAGHTSNIKGALFLSDGKRIISASDDKTVRLWSLETCQEVQQLTFDTP-PTSLTLSPD 583

Query: 109 GNFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQIITSSG-DTTCA 167
            N +      NI   Y   T     +   E P     +S        +   + G D    
Sbjct: 584 KNTIIVTHSQNIA-FYQADTLREMKKFEAEAP-----ISSASLHQSERFFVAGGEDFKMY 745

Query: 168 LWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLW 211
            +D ETG++   F GH G V  +  +PDG  + SG+ D +++LW
Sbjct: 746 KFDYETGKEIESFKGHFGPVHCVRFSPDGELYASGSEDGTLRLW 877

 Score = 47.0 bits (110), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 31/121 (25%), Positives = 55/121 (45%), Gaps = 1/121 (0%)
 Frame = +2

Query: 221 TFIGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRADQELLMYSHDNIICGITSVAFSR 280
           TF GH+  +             TG+ D + +++D    +EL  +SH +I+    SV FS 
Sbjct: 158 TFEGHKGAVWGATLNREATRAATGAADFSAKIWDAEKGEELQTFSHKHIV---KSVDFSH 328

Query: 281 SGRLLLAGYDDFNCNIWDAMKGD-RAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIW 339
            G  LL G ++    ++D +  D      AGH + +       DG  + + S D  +++W
Sbjct: 329 DGTALLTGSNEKLLKVFDLVNTDAEPKSFAGHTSNIKGALFLSDGKRIISASDDKTVRLW 508

Query: 340 N 340
           +
Sbjct: 509 S 511

 Score = 30.0 bits (66), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 10/36 (27%), Positives = 19/36 (52%)
 Frame = +2

Query: 49  RTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDS 84
            + +GH   ++ + +  D  L  S S+DG L +W +
Sbjct: 776 ESFKGHFGPVHCVRFSPDGELYASGSEDGTLRLWQT 883
>30256
          Length = 961

 Score = 77.0 bits (188), Expect = 1e-14,   Method: Compositional matrix adjust.
 Identities = 67/238 (28%), Positives = 110/238 (46%), Gaps = 5/238 (2%)
 Frame = +3

Query: 108 SGNFVACGGLDNICSIYSLKTREGNVRV-SRELPGHTGYLSCCRFLDDNQIITSSGDTTC 166
           +GN V  G  D      SLK    +  V +  L GH+  + C   L   ++++ S D T 
Sbjct: 69  TGNTVISGSTDR-----SLKVWNADTGVCTHTLYGHSSTVRCLS-LSGKKVVSGSRDATL 230

Query: 167 ALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHE 226
            +WDIE+G       GH   V  +    DG+  VSGA D ++++WD   + C  T  GH 
Sbjct: 231 RVWDIESGHCLNVLLGHMAAVRCVQY--DGKRVVSGAXDYTVRVWDPDTASCLHTLQGHT 404

Query: 227 SDINAVAFFPNGYAFTTGSDDATCRLFDLRADQEL-LMYSHDNIICGITSVAFSRSGRLL 285
           + + ++ F  +G    +GS D + R++D+R  + +  +  H ++  G+          LL
Sbjct: 405 NRVYSLQF--DGVYVVSGSLDTSIRVWDVRCGKLVHTLMGHQSLTSGL-----ELKDNLL 563

Query: 286 LAGYDDFNCNIWDAMKGDRAGVLAG---HDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
           ++G  D    +WD   G     L G   H + V+CL    +   V T S D  +K+W+
Sbjct: 564 VSGNADSTVKVWDVHTGKCLQTLLGPNKHRSAVTCLQF--NKKFVVTCSDDGTVKLWD 731
>12806
          Length = 961

 Score = 76.6 bits (187), Expect = 1e-14,   Method: Compositional matrix adjust.
 Identities = 53/193 (27%), Positives = 91/193 (47%), Gaps = 6/193 (3%)
 Frame = +3

Query: 48  RRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAP 107
           R+TL GH   I  +    DSR  +S+S D  L +WD    +        +  V+T A++P
Sbjct: 144 RKTLTGHSHFISDLALSADSRFALSSSWDATLRLWDIKKGSTTSRFINHTRDVLTVAFSP 323

Query: 108 SGNFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQ---IITSSGDT 164
               +A GG D    I+++    G  + + +   HT +++C RF  D +   ++++S D 
Sbjct: 324 DNRQIASGGRDKNLKIWNIM---GECKYTVDANAHTDWVTCVRFHQDTKNPIVVSASNDK 494

Query: 165 TCALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIG 224
           T  +WD  T      F GH   + +L ++ +    VSG+ D     W+V +     +F+G
Sbjct: 495 TIKVWDNHTMTLKNTFVGHKAQITALDMSTN--YLVSGSKDGIAMTWNVAEG----SFVG 656

Query: 225 H---ESDINAVAF 234
               +  INA+ F
Sbjct: 657 KIDCDDQINAIKF 695

 Score = 62.8 bits (151), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 53/211 (25%), Positives = 95/211 (45%), Gaps = 13/211 (6%)
 Frame = +3

Query: 111 FVACGGLDNICSIYSL-KTREGNVRVS-----RELPGHTGYLSCCRFLDDNQI-ITSSGD 163
           F+  GG DN   ++ L   ++G+   +     + L GH+ ++S      D++  ++SS D
Sbjct: 51  FLISGGRDNNIIVWDL*PKKDGDEDQTWGVPRKTLTGHSHFISDLALSADSRFALSSSWD 230

Query: 164 TTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTF- 222
            T  LWDI+ G  T  F  H+ DV++++ +PD R   SG  D ++K+W++    C+ T  
Sbjct: 231 ATLRLWDIKKGSTTSRFINHTRDVLTVAFSPDNRQIASGGRDKNLKIWNIMGE-CKYTVD 407

Query: 223 -IGHESDINAVAFFPN--GYAFTTGSDDATCRLFDLRADQELLMYSHDNIICGITS--VA 277
              H   +  V F  +       + S+D T +++D          +  N   G  +   A
Sbjct: 408 ANAHTDWVTCVRFHQDTKNPIVVSASNDKTIKVWDNHT------MTLKNTFVGHKAQITA 569

Query: 278 FSRSGRLLLAGYDDFNCNIWDAMKGDRAGVL 308
              S   L++G  D     W+  +G   G +
Sbjct: 570 LDMSTNYLVSGSKDGIAMTWNVAEGSFVGKI 662

 Score = 30.0 bits (66), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 19/67 (28%), Positives = 31/67 (46%), Gaps = 10/67 (14%)
 Frame = +3

Query: 284 LLLAGYDDFNCNIWD---AMKGDR-------AGVLAGHDNRVSCLGVTDDGMAVATGSWD 333
            L++G  D N  +WD      GD           L GH + +S L ++ D     + SWD
Sbjct: 51  FLISGGRDNNIIVWDL*PKKDGDEDQTWGVPRKTLTGHSHFISDLALSADSRFALSSSWD 230

Query: 334 SFLKIWN 340
           + L++W+
Sbjct: 231 ATLRLWD 251
>00561
          Length = 1003

 Score = 74.3 bits (181), Expect = 6e-14,   Method: Compositional matrix adjust.
 Identities = 61/246 (24%), Positives = 108/246 (43%), Gaps = 13/246 (5%)
 Frame = -3

Query: 66  DSRLLVSASQDGKLIIWD---------SYTTNKVHAIPLRSSWVMTCAYAPSGNFVACGG 116
           D   ++SAS+D  LI+W           Y   +++     S ++     +  GN+   G 
Sbjct: 977 DPDTIISASRDKTLIVWKLTRDEDTNYGYPQKRLYG---HSHFISDVVLSSDGNYALSGS 807

Query: 117 LDNICSIYSLKTREGNVRVSRELPGHTG-YLSCCRFLDDNQIITSSGDTTCALWD-IETG 174
            D    ++ L       + +R   GHT   LS     D+ QI++ S D T  LW+ +   
Sbjct: 806 WDQTLRLWDLAAG----KTTRRFEGHTKDVLSVAFSADNRQIVSGSRDKTIKLWNTLAEC 639

Query: 175 QQTVGFAGHSGDVMSLSLAPDGRTFVSGAC--DASIKLWDVRDSMCRQTFIGHESDINAV 232
           + T+   GH+  V  +  +P+    +  +C  D ++K+W++ +   +    GH   +N V
Sbjct: 638 KFTIQEDGHTDWVSCVRFSPNHSNPIIVSCGWDRTVKVWNLANCKLKNNHHGHNGYLNTV 459

Query: 233 AFFPNGYAFTTGSDDATCRLFDLRADQELLMYSHDNIICGITSVAFSRSGRLLLAGYDDF 292
              P+G   T+G  D+   L+DL   + L    H++I   I ++ FS +   L   Y   
Sbjct: 458 TVSPDGSLCTSGGKDSKALLWDLNDGKNLYTLEHNDI---INALCFSPNRYWLCVAYGP- 291

Query: 293 NCNIWD 298
           +  IWD
Sbjct: 290 SIKIWD 273

 Score = 69.3 bits (168), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 61/210 (29%), Positives = 96/210 (45%), Gaps = 6/210 (2%)
 Frame = -3

Query: 137 RELPGHTGYLSCCRFLDD-NQIITSSGDTTCALWDIETGQQTVGFAGHSGDVMSLSLAPD 195
           + L GH+ ++S      D N  ++ S D T  LWD+  G+ T  F GH+ DV+S++ + D
Sbjct: 884 KRLYGHSHFISDVVLSSDGNYALSGSWDQTLRLWDLAAGKTTRRFEGHTKDVLSVAFSAD 705

Query: 196 GRTFVSGACDASIKLWDVRDSMCRQTFI--GHESDINAVAFFPN--GYAFTTGSDDATCR 251
            R  VSG+ D +IKLW+   + C+ T    GH   ++ V F PN       +   D T +
Sbjct: 704 NRQIVSGSRDKTIKLWNTL-AECKFTIQEDGHTDWVSCVRFSPNHSNPIIVSCGWDRTVK 528

Query: 252 LFDLRADQELLMYSHDNIICGITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDRAGVLAGH 311
           +++L   +  L  +H      + +V  S  G L  +G  D    +WD   G     L  +
Sbjct: 527 VWNLANCK--LKNNHHGHNGYLNTVTVSPDGSLCTSGGKDSKALLWDLNDGKNLYTLEHN 354

Query: 312 D-NRVSCLGVTDDGMAVATGSWDSFLKIWN 340
           D     C       + VA G     +KIW+
Sbjct: 353 DIINALCFSPNRYWLCVAYG---PSIKIWD 273

 Score = 63.5 bits (153), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 48/197 (24%), Positives = 81/197 (41%), Gaps = 3/197 (1%)
 Frame = -3

Query: 46  RTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAY 105
           +T R   GH   + ++ +  D+R +VS S+D  + +W++                     
Sbjct: 767 KTTRRFEGHTKDVLSVAFSADNRQIVSGSRDKTIKLWNTL-------------------- 648

Query: 106 APSGNFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDD--NQIITSSG- 162
                                       + + +  GHT ++SC RF  +  N II S G 
Sbjct: 647 -------------------------AECKFTIQEDGHTDWVSCVRFSPNHSNPIIVSCGW 543

Query: 163 DTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTF 222
           D T  +W++   +      GH+G + +++++PDG    SG  D+   LWD+ D     T 
Sbjct: 542 DRTVKVWNLANCKLKNNHHGHNGYLNTVTVSPDGSLCTSGGKDSKALLWDLNDGKNLYT- 366

Query: 223 IGHESDINAVAFFPNGY 239
           + H   INA+ F PN Y
Sbjct: 365 LEHNDIINALCFSPNRY 315
>27465
          Length = 658

 Score = 72.8 bits (177), Expect = 2e-13,   Method: Compositional matrix adjust.
 Identities = 37/104 (35%), Positives = 54/104 (51%), Gaps = 1/104 (0%)
 Frame = -1

Query: 157 IITSSGDTTCALWDIETGQQTVGFAGHSGDVMSLSLA-PDGRTFVSGACDASIKLWDVRD 215
            IT S D TC +WD  + ++     GH   V +++   P G   ++G+ D + KLW   D
Sbjct: 316 FITGSYDRTCKIWDTASAEELHTLEGHRNVVYAIAFNNPFGDKVITGSFDKTCKLWSTAD 137

Query: 216 SMCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRADQ 259
             C  T  GH ++I  V+F P+     TGS D TCRL+D+   Q
Sbjct: 136 GKCYHTLRGHTAEIVCVSFNPSSTLIATGSMDTTCRLWDVEKAQ 5

 Score = 59.7 bits (143), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 36/119 (30%), Positives = 58/119 (48%), Gaps = 2/119 (1%)
 Frame = -1

Query: 224 GHESDINAVAFFPNGYAFTTGSDDATCRLFDLRADQEL-LMYSHDNIICGITSVAFSRS- 281
            H   +  VAF  +G +F TGS D TC+++D  + +EL  +  H N++  I   AF+   
Sbjct: 367 AHILPLTNVAFNKSGSSFITGSYDRTCKIWDTASAEELHTLEGHRNVVYAI---AFNNPF 197

Query: 282 GRLLLAGYDDFNCNIWDAMKGDRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
           G  ++ G  D  C +W    G     L GH   + C+        +ATGS D+  ++W+
Sbjct: 196 GDKVITGSFDKTCKLWSTADGKCYHTLRGHTAEIVCVSFNPSSTLIATGSMDTTCRLWD 20

 Score = 59.3 bits (142), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 38/130 (29%), Positives = 62/130 (47%), Gaps = 2/130 (1%)
 Frame = -1

Query: 49  RTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYA-P 107
           + LR H+  +  + +       ++ S D    IWD+ +  ++H +    + V   A+  P
Sbjct: 379 KVLRAHILPLTNVAFNKSGSSFITGSYDRTCKIWDTASAEELHTLEGHRNVVYAIAFNNP 200

Query: 108 SGNFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQII-TSSGDTTC 166
            G+ V  G  D  C ++S  T +G  +    L GHT  + C  F   + +I T S DTTC
Sbjct: 199 FGDKVITGSFDKTCKLWS--TADG--KCYHTLRGHTAEIVCVSFNPSSTLIATGSMDTTC 32

Query: 167 ALWDIETGQQ 176
            LWD+E  Q+
Sbjct: 31  RLWDVEKAQR 2

 Score = 56.2 bits (134), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 38/127 (29%), Positives = 63/127 (49%), Gaps = 4/127 (3%)
 Frame = -1

Query: 182 GHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAF-FPNGYA 240
            H   + +++    G +F++G+ D + K+WD   +    T  GH + + A+AF  P G  
Sbjct: 367 AHILPLTNVAFNKSGSSFITGSYDRTCKIWDTASAEELHTLEGHRNVVYAIAFNNPFGDK 188

Query: 241 FTTGSDDATCRLF---DLRADQELLMYSHDNIICGITSVAFSRSGRLLLAGYDDFNCNIW 297
             TGS D TC+L+   D +    L  ++ + I+C    V+F+ S  L+  G  D  C +W
Sbjct: 187 VITGSFDKTCKLWSTADGKCYHTLRGHTAE-IVC----VSFNPSSTLIATGSMDTTCRLW 23

Query: 298 DAMKGDR 304
           D  K  R
Sbjct: 22  DVEKAQR 2
>02960
          Length = 1577

 Score = 66.2 bits (160), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 49/159 (30%), Positives = 80/159 (50%), Gaps = 6/159 (3%)
 Frame = +2

Query: 139  LPGHTGYLSCCRFLDDNQIITSSGDTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGRT 198
            L GH   +S  R+LD ++++TSS D +  LWD+ T QQT    G S  V+ ++ +P    
Sbjct: 947  LSGHAEAVSAVRWLDPHRVVTSSWDHSLRLWDLHTAQQTSLIQG-SKAVLDVAYSPLSHM 1123

Query: 199  FVSGACDASIKLWDVRDS---MCRQTFIGHESDINAVAFFPN-GYAFTTGSDDATCRLFD 254
             ++G+ D  ++L D R S     +  F  H   +  V + P   + F +GS D   +L+D
Sbjct: 1124 LITGSADRHVRLVDPRCSEGETVKCAFTSHTGWVTGVDWSPTREHLFLSGSYDNVLKLWD 1303

Query: 255  LRADQELL--MYSHDNIICGITSVAFSRSGRLLLAGYDD 291
             R+ +  L  M  H++    I +V +S    LL  G D+
Sbjct: 1304 TRSPKATLYDMNWHED---RILAVDWSIPELLLSGGVDN 1411

 Score = 39.7 bits (91), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 45/192 (23%), Positives = 76/192 (39%), Gaps = 9/192 (4%)
 Frame = +2

Query: 158 ITSSGDTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGR-----TFVSGACDASIKLW- 211
           ++ S D T  LW  + G+  +   GH+  V  ++           TFV+G+ D +  +W 
Sbjct: 527 LSGSYDNTVRLWSTK-GEAIMTIPGHTSPVKCVAWIKHDESSGVSTFVTGSHDQTALVWQ 703

Query: 212 ---DVRDSMCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRADQELLMYSHDN 268
              +  +  CR +  GH + ++ VA  P+     TGS            D+ L ++S D 
Sbjct: 704 WQRETNEVDCRLSCRGHAASVDCVAVSPDSQQMCTGS-----------WDKMLKLWSTDC 850

Query: 269 IICGITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDRAGVLAGHDNRVSCLGVTDDGMAVA 328
            + G  S    R  +   +        +           L+GH   VS +   D    V 
Sbjct: 851 NVDGDQSEDTERPSKKKKSAKSTTQTRV-------PVLTLSGHAEAVSAVRWLD-PHRVV 1006

Query: 329 TGSWDSFLKIWN 340
           T SWD  L++W+
Sbjct: 1007TSSWDHSLRLWD 1042
>19949
          Length = 903

 Score = 65.9 bits (159), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 40/149 (26%), Positives = 68/149 (45%), Gaps = 1/149 (0%)
 Frame = +2

Query: 100 VMTCAYAPSGNFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQ-II 158
           V +  + P G + A G +D    ++ ++ R+G +   +   GHTG + C RF  D + I 
Sbjct: 2   VKSLDFHPYGAYTASGSMDCNVKLWDIR-RKGCIYTYK---GHTGCVCCLRFSPDGRWIA 169

Query: 159 TSSGDTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMC 218
           ++S D    LWD+  G+       H   V ++   P      SG+ D ++K WD+     
Sbjct: 170 SASEDGLVKLWDLTAGKLLTDLKLHRDAVNTIEFHPHEFLLASGSADRTVKFWDLETFQL 349

Query: 219 RQTFIGHESDINAVAFFPNGYAFTTGSDD 247
             T     + I ++ F P+G    +GS D
Sbjct: 350 ISTTEPEANSIRSILFHPDGVCLYSGSKD 436

 Score = 62.0 bits (149), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 44/156 (28%), Positives = 70/156 (44%), Gaps = 2/156 (1%)
 Frame = +2

Query: 187 VMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTTGSD 246
           V SL   P G    SG+ D ++KLWD+R   C  T+ GH   +  + F P+G    + S+
Sbjct: 2   VKSLDFHPYGAYTASGSMDCNVKLWDIRRKGCIYTYKGHTGCVCCLRFSPDGRWIASASE 181

Query: 247 DATCRLFDLRADQEL--LMYSHDNIICGITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDR 304
           D   +L+DL A + L  L    D     + ++ F     LL +G  D     WD      
Sbjct: 182 DGLVKLWDLTAGKLLTDLKLHRD----AVNTIEFHPHEFLLASGSADRTVKFWDLETFQL 349

Query: 305 AGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
                   N +  +    DG+ + +GS D+ LK+++
Sbjct: 350 ISTTEPEANSIRSILFHPDGVCLYSGSKDT-LKVYH 454

 Score = 37.7 bits (86), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 30/135 (22%), Positives = 54/135 (40%), Gaps = 1/135 (0%)
 Frame = +2

Query: 72  SASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFVACGGLDNICSIYSLKTREG 131
           S S D  + +WD      ++     +  V    ++P G ++A    D +  ++ L     
Sbjct: 44  SGSMDCNVKLWDIRRKGCIYTYKGHTGCVCCLRFSPDGRWIASASEDGLVKLWDLTAG-- 217

Query: 132 NVRVSRELPGHTGYLSCCRFLDDNQIITS-SGDTTCALWDIETGQQTVGFAGHSGDVMSL 190
             ++  +L  H   ++   F     ++ S S D T   WD+ET Q        +  + S+
Sbjct: 218 --KLLTDLKLHRDAVNTIEFHPHEFLLASGSADRTVKFWDLETFQLISTTEPEANSIRSI 391

Query: 191 SLAPDGRTFVSGACD 205
              PDG    SG+ D
Sbjct: 392 LFHPDGVCLYSGSKD 436

 Score = 37.0 bits (84), Expect = 0.011,   Method: Compositional matrix adjust.
 Identities = 21/79 (26%), Positives = 35/79 (44%)
 Frame = +2

Query: 50  TLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSG 109
           T +GH   +  + +  D R + SAS+DG + +WD      +  + L    V T  + P  
Sbjct: 104 TYKGHTGCVCCLRFSPDGRWIASASEDGLVKLWDLTAGKLLTDLKLHRDAVNTIEFHPHE 283

Query: 110 NFVACGGLDNICSIYSLKT 128
             +A G  D     + L+T
Sbjct: 284 FLLASGSADRTVKFWDLET 340
>17602
          Length = 481

 Score = 64.7 bits (156), Expect = 5e-11,   Method: Compositional matrix adjust.
 Identities = 40/135 (29%), Positives = 62/135 (45%), Gaps = 3/135 (2%)
 Frame = +3

Query: 209 KLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRADQELLMYSHDN 268
           ++WDV+   C +T   H   + AV F  +G    + S D  CR++D  + Q L     D+
Sbjct: 3   RIWDVKTGKCLKTLPAHSDPVTAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLXTLIDDD 182

Query: 269 IICGITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDRAGVLAGHDNRVSCLGV---TDDGM 325
               ++ V FS +G+ +LA   D    +WD  KG       GH N   C+        G 
Sbjct: 183 NP-PVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYVGHRNEKYCIFANFSVTGGK 359

Query: 326 AVATGSWDSFLKIWN 340
            + +GS D+ + IWN
Sbjct: 360 WIVSGSEDNMVYIWN 404

 Score = 55.8 bits (133), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 33/124 (26%), Positives = 61/124 (49%), Gaps = 5/124 (4%)
 Frame = +3

Query: 137 RELPGHTGYLSCCRF-LDDNQIITSSGDTTCALWDIETGQQTVGFAGHSGDVMS-LSLAP 194
           + LP H+  ++   F  D + I++SS D  C +WD  +GQ            +S +  +P
Sbjct: 36  KTLPAHSDPVTAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLXTLIDDDNPPVSFVKFSP 215

Query: 195 DGRTFVSGACDASIKLWDVRDSMCRQTFIGHESD---INAVAFFPNGYAFTTGSDDATCR 251
           +G+  ++   D ++KLWD     C +T++GH ++   I A      G    +GS+D    
Sbjct: 216 NGKYILAATLDNTLKLWDYSKGKCLKTYVGHRNEKYCIFANFSVTGGKWIVSGSEDNMVY 395

Query: 252 LFDL 255
           +++L
Sbjct: 396 IWNL 407

 Score = 37.4 bits (85), Expect = 0.009,   Method: Compositional matrix adjust.
 Identities = 22/77 (28%), Positives = 39/77 (50%), Gaps = 1/77 (1%)
 Frame = +3

Query: 49  RTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHA-IPLRSSWVMTCAYAP 107
           +TL  H   + A+H+  D  L+VS+S DG   IWD+ +   +   I   +  V    ++P
Sbjct: 36  KTLPAHSDPVTAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLXTLIDDDNPPVSFVKFSP 215

Query: 108 SGNFVACGGLDNICSIY 124
           +G ++    LDN   ++
Sbjct: 216 NGKYILAATLDNTLKLW 266
>03395
          Length = 2795

 Score = 59.3 bits (142), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 47/167 (28%), Positives = 72/167 (43%), Gaps = 2/167 (1%)
 Frame = +2

Query: 51  LRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGN 110
           ++ H  K+ A+   T+ R  VSAS DG  IIWD   TN    I L ++      +     
Sbjct: 134 MKEHKGKVTAIQIHTNDRCCVSASTDGSTIIWD-LITNTRSQIVLANTLFKCVCFGGKDL 310

Query: 111 FVACGGLDNICSIYSLKTREGNVRVSRELPG-HTGYLSCCRFLDDNQIITSSG-DTTCAL 168
            +   G D+    + +    G+  + REL G  TG ++      D Q I + G D+   L
Sbjct: 311 HILTSGTDHKIGYWEV----GDGGLLRELEGSQTGAINTIDIDRDGQTILTGGEDSLLKL 478

Query: 169 WDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRD 215
           W    G+ T    GHS  +    + P+    VSG  D ++ +W   D
Sbjct: 479 WRYNEGEVTHTGIGHSNQITKARICPNRHYIVSGGEDGALHIWKFPD 619

 Score = 45.8 bits (107), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 39/193 (20%), Positives = 75/193 (38%), Gaps = 8/193 (4%)
 Frame = +2

Query: 156 QIITSSGDTTCALWDI--------ETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDAS 207
           ++++  G+    +WDI          G        H G V ++ +  + R  VS + D S
Sbjct: 38  KLVSGGGEGQVRVWDIVKDMLTGKTRGDLVANMKEHKGKVTAIQIHTNDRCCVSASTDGS 217

Query: 208 IKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRADQELLMYSHD 267
             +WD+  +   Q  + + +    V F        T   D     +++  D  LL     
Sbjct: 218 TIIWDLITNTRSQIVLAN-TLFKCVCFGGKDLHILTSGTDHKIGYWEV-GDGGLLRELEG 391

Query: 268 NIICGITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDRAGVLAGHDNRVSCLGVTDDGMAV 327
           +    I ++   R G+ +L G +D    +W   +G+      GH N+++   +  +   +
Sbjct: 392 SQTGAINTIDIDRDGQTILTGGEDSLLKLWRYNEGEVTHTGIGHSNQITKARICPNRHYI 571

Query: 328 ATGSWDSFLKIWN 340
            +G  D  L IW 
Sbjct: 572 VSGGEDGALHIWK 610

 Score = 40.8 bits (94), Expect = 9e-04,   Method: Compositional matrix adjust.
 Identities = 34/162 (20%), Positives = 64/162 (39%), Gaps = 9/162 (5%)
 Frame = +2

Query: 187 VMSLSLAPDGRTFVSGACDASIKLWD-VRDSMCRQT-------FIGHESDINAVAFFPNG 238
           V ++++   G   VSG  +  +++WD V+D +  +T          H+  + A+    N 
Sbjct: 5   VTAIAVTSCGTKLVSGGGEGQVRVWDIVKDMLTGKTRGDLVANMKEHKGKVTAIQIHTND 184

Query: 239 YAFTTGSDDATCRLFDLRADQELLMYSHDNIICGITSVAFSRSGRLLLAGYDDFNCNIWD 298
               + S D +  ++DL  +    +   + +      V F      +L    D     W+
Sbjct: 185 RCCVSASTDGSTIIWDLITNTRSQIVLANTL---FKCVCFGGKDLHILTSGTDHKIGYWE 355

Query: 299 AMKGDRAGVLAG-HDNRVSCLGVTDDGMAVATGSWDSFLKIW 339
              G     L G     ++ + +  DG  + TG  DS LK+W
Sbjct: 356 VGDGGLLRELEGSQTGAINTIDIDRDGQTILTGGEDSLLKLW 481

 Score = 28.5 bits (62), Expect = 3.6,   Method: Compositional matrix adjust.
 Identities = 17/77 (22%), Positives = 34/77 (44%), Gaps = 8/77 (10%)
 Frame = +2

Query: 272 GITSVAFSRSGRLLLAGYDDFNCNIWDAMK--------GDRAGVLAGHDNRVSCLGVTDD 323
           G+T++A +  G  L++G  +    +WD +K        GD    +  H  +V+ + +  +
Sbjct: 2   GVTAIAVTSCGTKLVSGGGEGQVRVWDIVKDMLTGKTRGDLVANMKEHKGKVTAIQIHTN 181

Query: 324 GMAVATGSWDSFLKIWN 340
                + S D    IW+
Sbjct: 182 DRCCVSASTDGSTIIWD 232
>01805
          Length = 2124

 Score = 58.9 bits (141), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 66/270 (24%), Positives = 113/270 (41%), Gaps = 35/270 (12%)
 Frame = -1

Query: 64  GTDSRLLVSASQDGKLIIWDSYTTNK------VH------AIPLRSSWVMTCAY--APSG 109
            TD+ +L    Q G L + D Y  N+      VH      + PL   W+    Y  AP G
Sbjct: 897 ATDNLILCGRCQ-GDLSVLDVYVYNEDNNQLYVHHDYLLSSFPLALEWLNFDGYDNAP-G 724

Query: 110 NFVACGGLDNICSIYSLKTREG----------------NVRVSRELPGHT-GYLSCCRFL 152
           NFVA G ++ +  I+ L   E                  ++    + GHT   L      
Sbjct: 723 NFVAIGSMEPVIEIWDLDIMESVGPTLTLGSKPKKTKKKMKQKESVTGHTQAVLDLSWNR 544

Query: 153 DDNQIITS-SGDTTCALWDIETGQQTVGFAGHSGDVMSLSLAP-DGRTFVSGACDASIKL 210
           +   ++ S S DTT ALWD+  G+  + F  HS +V   +  P + +T ++G+ D ++K+
Sbjct: 543 NARHVLASASADTTVALWDLSEGKMAMNFTQHSREVQCCNWHPQEEQTLLTGSFDNTVKV 364

Query: 211 WDVRDS-MCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRADQELLMY-SHDN 268
            D R +  C +++        AV    N       +D      FD+R ++ +    +H +
Sbjct: 363 VDCRSAETCHKSWTVEGEVEKAVWNHHNPLQLLACTDKGMVYCFDIRHEKPVFSVGAHSS 184

Query: 269 IICGITSVAFSRSGRLLLAGYDDFNCNIWD 298
            + G+     S+   L++   +D    +WD
Sbjct: 183 CVTGV--CLSSQIPGLMITTSEDKTMKVWD 100

 Score = 27.3 bits (59), Expect = 8.0,   Method: Compositional matrix adjust.
 Identities = 17/69 (24%), Positives = 32/69 (46%), Gaps = 2/69 (2%)
 Frame = -1

Query: 272 GITSVAFSRSGRLLLAGYD-DFNCNIWDAMKGDRAGVLAGHDNRVSCLG-VTDDGMAVAT 329
            +  ++++R+ R +LA    D    +WD  +G  A     H   V C      +   + T
Sbjct: 570 AVLDLSWNRNARHVLASASADTTVALWDLSEGKMAMNFTQHSREVQCCNWHPQEEQTLLT 391

Query: 330 GSWDSFLKI 338
           GS+D+ +K+
Sbjct: 390 GSFDNTVKV 364
>02090
          Length = 1841

 Score = 57.8 bits (138), Expect = 7e-09,   Method: Compositional matrix adjust.
 Identities = 43/178 (24%), Positives = 77/178 (43%), Gaps = 2/178 (1%)
 Frame = -3

Query: 164  TTCALWDIETGQQTVG--FAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQT 221
            +T ++WD+ T    +       +    +L+++PDG+   S   D +I +WD+ +    + 
Sbjct: 1692 STLSIWDLATPTPRIKAELTSSAPACYALAISPDGKVCFSCCSDGNIAVWDLHNQTLVRQ 1513

Query: 222  FIGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRADQELLMYSHDNIICGITSVAFSRS 281
            F GH    + +   P+G    TG  D T R +DLR  ++L  +   +    I S+ +  +
Sbjct: 1512 FQGHTDGASCIDISPDGTKLWTGGLDNTVRSWDLREGRQLQQHDFSS---QIFSLGYCPT 1342

Query: 282  GRLLLAGYDDFNCNIWDAMKGDRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIW 339
            G  L  G +  N  +    K D+   L  H++ V  L     G    +   D+ L  W
Sbjct: 1341 GEWLAVGMESSNVEVLHHSKPDKYQ-LHLHESCVLSLKFAYCGKWFVSTGKDNLLNAW 1171

 Score = 48.5 bits (114), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 38/171 (22%), Positives = 69/171 (40%)
 Frame = -3

Query: 163  DTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTF 222
            D   A+WD+        F GH+     + ++PDG    +G  D +++ WD+R+    Q  
Sbjct: 1563 DGNIAVWDLHNQTLVRQFQGHTDGASCIDISPDGTKLWTGGLDNTVRSWDLREGRQLQQH 1384

Query: 223  IGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRADQELLMYSHDNIICGITSVAFSRSG 282
                S I ++ + P G     G + +   +       +  ++ H++    + S+ F+  G
Sbjct: 1383 -DFSSQIFSLGYCPTGEWLAVGMESSNVEVLHHSKPDKYQLHLHESC---VLSLKFAYCG 1216

Query: 283  RLLLAGYDDFNCNIWDAMKGDRAGVLAGHDNRVSCLGVTDDGMAVATGSWD 333
            +  ++   D   N W    G          + +SC    DD   V TGS D
Sbjct: 1215 KWFVSTGKDNLLNAWRTPYGASIFQSKESSSVLSCDIAADDKYIV-TGSGD 1066

 Score = 35.4 bits (80), Expect = 0.037,   Method: Compositional matrix adjust.
 Identities = 17/66 (25%), Positives = 32/66 (48%)
 Frame = -3

Query: 275  SVAFSRSGRLLLAGYDDFNCNIWDAMKGDRAGVLAGHDNRVSCLGVTDDGMAVATGSWDS 334
            ++A S  G++  +   D N  +WD           GH +  SC+ ++ DG  + TG  D+
Sbjct: 1611 ALAISPDGKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISPDGTKLWTGGLDN 1432

Query: 335  FLKIWN 340
             ++ W+
Sbjct: 1431 TVRSWD 1414

 Score = 34.7 bits (78), Expect = 0.062,   Method: Compositional matrix adjust.
 Identities = 45/211 (21%), Positives = 71/211 (33%), Gaps = 1/211 (0%)
 Frame = -3

Query: 46   RTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAY 105
            R +  L       YA+    D ++  S   DG + +WD +    V      +        
Sbjct: 1653 RIKAELTSSAPACYALAISPDGKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGASCIDI 1474

Query: 106  APSGNFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQIITSSGDTT 165
            +P G  +  GGLDN  ++ S   REG      +       L  C   +   +   S +  
Sbjct: 1473 SPDGTKLWTGGLDN--TVRSWDLREGRQLQQHDFSSQIFSLGYCPTGEWLAVGMESSNVE 1300

Query: 166  CALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGH 225
                   +         H   V+SL  A  G+ FVS   D  +  W  R       F   
Sbjct: 1299 VLH---HSKPDKYQLHLHESCVLSLKFAYCGKWFVSTGKDNLLNAW--RTPYGASIFQSK 1135

Query: 226  E-SDINAVAFFPNGYAFTTGSDDATCRLFDL 255
            E S + +     +     TGS D    L+++
Sbjct: 1134 ESSSVLSCDIAADDKYIVTGSGDKKATLYEV 1042
>26107
          Length = 1338

 Score = 54.7 bits (130), Expect = 6e-08,   Method: Compositional matrix adjust.
 Identities = 43/150 (28%), Positives = 65/150 (43%), Gaps = 1/150 (0%)
 Frame = -3

Query: 153  DDNQIITSSGDTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTF-VSGACDASIKLW 211
            +D+Q +T+SGD T ALWD+ET  +   F GH   V S++  P       SGA D  I LW
Sbjct: 1054 NDSQCLTASGDQTVALWDVETTTKVTTFIGHKCSVRSVASCPSSPAQCASGARDGHIMLW 875

Query: 212  DVRDSMCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRADQELLMYSHDNIIC 271
            D R +  R+    H+         P        S  A  R     A  + +M +  ++ C
Sbjct: 874  DSRVNKKRE----HQPCSQVHQVCPQS---GHQSKPAKHRRIHRAAGPKGVMDTQQSVTC 716

Query: 272  GITSVAFSRSGRLLLAGYDDFNCNIWDAMK 301
                V +     ++ +G +D    +WD  K
Sbjct: 715  ----VLYQTDNLIISSGANDGCVKMWDTRK 638

 Score = 42.0 bits (97), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 46/193 (23%), Positives = 81/193 (41%), Gaps = 20/193 (10%)
 Frame = -3

Query: 101 MTCAYAPSGNFVACGGLDNIC-SIYSLKTREGNVRVSRELPGHT-----------GYLSC 148
           +TC    + N +   G ++ C  ++  +    N   S  +P HT           G ++ 
Sbjct: 724 VTCVLYQTDNLIISSGANDGCVKMWDTRKWYTNTTTSLPVPVHTFDYPGHMRRLKGIVTM 545

Query: 149 CRFLDDNQIITSSGDTTCALWDIETGQ----QTVGFAGHSGDVMSL--SLAPDGRTFVSG 202
           C     +Q+  S  D     + +  GQ    Q   +AGH  D   +  +++PDG+  +SG
Sbjct: 544 CMDPWKSQLFVSYTDNKVYRYQL-AGQYREPQEYVYAGHRNDTFFVRCAISPDGKYLLSG 368

Query: 203 ACDASIKLWDVRDSMCRQTF-IGHESDINAVAFFPNGY-AFTTGSDDATCRLFDLRADQE 260
           +   +  +W+V     R  F IGH  D++AV +         T SDD + R++   A + 
Sbjct: 367 SGRNTGVIWEVDKPNKRPLFLIGHTEDVSAVDWCSTDVCKLATVSDDRSLRIWRPDARER 188

Query: 261 LLMYSHDNIICGI 273
              ++ D  I G 
Sbjct: 187 ---HTEDPTISGF 158

 Score = 38.1 bits (87), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 36/168 (21%), Positives = 68/168 (40%), Gaps = 7/168 (4%)
 Frame = -3

Query: 180  FAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGY 239
            +  H+  V   S   +    ++ + D ++ LWDV  +    TFIGH+  + +VA  P+  
Sbjct: 1099 WXAHNNAVFDYSWISNDSQCLTASGDQTVALWDVETTTKVTTFIGHKCSVRSVASCPSSP 920

Query: 240  AF-TTGSDDATCRLFDLRADQELLMYSHDNIICGITSVAFSRSGRLLLAGYDDFNCNIWD 298
            A   +G+ D    L+D R +++      ++  C        +SG                
Sbjct: 919  AQCASGARDGHIMLWDSRVNKK-----REHQPCSQVHQVCPQSGHQSKPA---------- 785

Query: 299  AMKGDRAGVLAGH------DNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
              K  R    AG          V+C+    D + +++G+ D  +K+W+
Sbjct: 784  --KHRRIHRAAGPKGVMDTQQSVTCVLYQTDNLIISSGANDGCVKMWD 647
>03156
          Length = 1014

 Score = 54.7 bits (130), Expect = 6e-08,   Method: Compositional matrix adjust.
 Identities = 47/198 (23%), Positives = 81/198 (40%), Gaps = 12/198 (6%)
 Frame = +1

Query: 155 NQIITSSGDTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVR 214
           N + ++S D T  +W          F GH   V ++ L  D     SG+ D ++++WDV 
Sbjct: 94  NGMFSASRDKTIKMWQRGNSHSIRDFIGHDMVVTAIHLNTDNTLLCSGSRDNTVRIWDVE 273

Query: 215 DSMC-RQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRADQELLMYSHDNII--- 270
              C RQ  I  ++ +  V + P  +      +D   R++D R    +  ++    I   
Sbjct: 274 TGACLRQNNI-PQNLVTDVKWLPGSHLIIQAGEDKEVRIYDSRTLGIVRSFTKKQYIQMS 450

Query: 271 CGITSVAFSRSGRLLLAGYDDFNCN-----IWDAMKGDRAGVLAGHDNRV-SCLGV--TD 322
           C +T+      G+  L   + F  N     +W    G       GH   + +CL +    
Sbjct: 451 CDVTA-----DGQFCLTCSNGFGGNGCEATLWQLSDGSIQNEFKGHREAIEACLFLPSNQ 615

Query: 323 DGMAVATGSWDSFLKIWN 340
           D   +AT S D  +++WN
Sbjct: 616 DMTLIATASRDCSVRVWN 669

 Score = 51.2 bits (121), Expect = 6e-07,   Method: Compositional matrix adjust.
 Identities = 56/232 (24%), Positives = 93/232 (40%), Gaps = 16/232 (6%)
 Frame = +1

Query: 19  RDARKAC-GDSTLTQITAGLDPVGRIQMR----TRRTLRGHLAKIYAMHWGTDSRLLVSA 73
           R+  K C G S     +A  D   ++  R    + R   GH   + A+H  TD+ LL S 
Sbjct: 58  REITKVCYGASCNGMFSASRDKTIKMWQRGNSHSIRDFIGHDMVVTAIHLNTDNTLLCSG 237

Query: 74  SQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFVACGGLDNICSIYSLKTREGNV 133
           S+D  + IWD  T   +    +  + V    + P  + +   G D    IY  +T    +
Sbjct: 238 SRDNTVRIWDVETGACLRQNNIPQNLVTDVKWLPGSHLIIQAGEDKEVRIYDSRT----L 405

Query: 134 RVSRELPGHTGYLSCCRFLDDNQI-ITSS---GDTTC--ALWDIETGQQTVGFAGHSGDV 187
            + R           C    D Q  +T S   G   C   LW +  G     F GH   +
Sbjct: 406 GIVRSFTKKQYIQMSCDVTADGQFCLTCSNGFGGNGCEATLWQLSDGSIQNEFKGHREAI 585

Query: 188 MSLSLAPDGR--TFVSGAC-DASIKLWDV--RDSMCRQTFIGHESDINAVAF 234
            +    P  +  T ++ A  D S+++W++  ++ +C Q F G     + +A+
Sbjct: 586 EACLFLPSNQDMTLIATASRDCSVRVWNMFTKECVCEQNFEGTGPLTSMIAY 741

 Score = 46.6 bits (109), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 53/231 (22%), Positives = 97/231 (41%), Gaps = 12/231 (5%)
 Frame = +1

Query: 37  LDPVGRIQMRTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLR 96
           L  +GR++ R      GH  +I  + +G     + SAS+D  + +W    ++ +    + 
Sbjct: 13  LSKMGRLEDR----WTGHDREITKVCYGASCNGMFSASRDKTIKMWQRGNSHSIRDF-IG 177

Query: 97  SSWVMTCAYAPSGNFVAC-GGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDN 155
              V+T  +  + N + C G  DN   I+ ++T  G       +P +   ++  ++L  +
Sbjct: 178 HDMVVTAIHLNTDNTLLCSGSRDNTVRIWDVET--GACLRQNNIPQN--LVTDVKWLPGS 345

Query: 156 QIITSSG-DTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGR-------TFVSGACDAS 207
            +I  +G D    ++D  T      F       MS  +  DG+        F    C+A+
Sbjct: 346 HLIIQAGEDKEVRIYDSRTLGIVRSFTKKQYIQMSCDVTADGQFCLTCSNGFGGNGCEAT 525

Query: 208 IKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFT---TGSDDATCRLFDL 255
             LW + D   +  F GH   I A  F P+    T   T S D + R++++
Sbjct: 526 --LWQLSDGSIQNEFKGHREAIEACLFLPSNQDMTLIATASRDCSVRVWNM 672

 Score = 39.3 bits (90), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 28/121 (23%), Positives = 53/121 (43%), Gaps = 1/121 (0%)
 Frame = +1

Query: 180 FAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGY 239
           + GH  ++  +          S + D +IK+W   +S   + FIGH+  + A+    +  
Sbjct: 43  WTGHDREITKVCYGASCNGMFSASRDKTIKMWQRGNSHSIRDFIGHDMVVTAIHLNTDNT 222

Query: 240 AFTTGSDDATCRLFDLRADQELLMYSHDNIICG-ITSVAFSRSGRLLLAGYDDFNCNIWD 298
              +GS D T R++D+     L     +NI    +T V +     L++   +D    I+D
Sbjct: 223 LLCSGSRDNTVRIWDVETGACL---RQNNIPQNLVTDVKWLPGSHLIIQAGEDKEVRIYD 393

Query: 299 A 299
           +
Sbjct: 394 S 396

 Score = 28.1 bits (61), Expect = 5.5,   Method: Compositional matrix adjust.
 Identities = 16/68 (23%), Positives = 29/68 (42%)
 Frame = +1

Query: 273 ITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDRAGVLAGHDNRVSCLGVTDDGMAVATGSW 332
           IT V +  S   + +   D    +W            GHD  V+ + +  D   + +GS 
Sbjct: 64  ITKVCYGASCNGMFSASRDKTIKMWQRGNSHSIRDFIGHDMVVTAIHLNTDNTLLCSGSR 243

Query: 333 DSFLKIWN 340
           D+ ++IW+
Sbjct: 244 DNTVRIWD 267
>01327
          Length = 2215

 Score = 54.3 bits (129), Expect = 8e-08,   Method: Compositional matrix adjust.
 Identities = 47/198 (23%), Positives = 81/198 (40%), Gaps = 12/198 (6%)
 Frame = +3

Query: 155 NQIITSSGDTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVR 214
           N + ++S D T  +W          F GH   V ++ L  D     SG+ D ++++WDV 
Sbjct: 204 NGMFSASRDKTIKMWQRGNSHSIRDFIGHDMVVTAIHLNTDNTLLCSGSRDNTVRIWDVE 383

Query: 215 DSMC-RQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRADQELLMYSHDNII--- 270
              C RQ  I  ++ +  V + P  +      +D   R++D R    +  ++    I   
Sbjct: 384 TGACLRQNNI-PQNLVTDVKWLPGSHLIIQAGEDKEVRIYDSRTLGIVRSFTKKQYIQMS 560

Query: 271 CGITSVAFSRSGRLLLAGYDDFNCN-----IWDAMKGDRAGVLAGHDNRV-SCLGV--TD 322
           C +T+      G+  L   + F  N     +W    G       GH   + +CL +    
Sbjct: 561 CDVTA-----DGQFCLTCSNGFGGNGCEATLWQLSDGSIQNEFKGHREAIEACLFLPSNQ 725

Query: 323 DGMAVATGSWDSFLKIWN 340
           D   +AT S D  +++WN
Sbjct: 726 DMTLIATASRDCSVRVWN 779

 Score = 51.2 bits (121), Expect = 6e-07,   Method: Compositional matrix adjust.
 Identities = 56/232 (24%), Positives = 93/232 (40%), Gaps = 16/232 (6%)
 Frame = +3

Query: 19  RDARKAC-GDSTLTQITAGLDPVGRIQMR----TRRTLRGHLAKIYAMHWGTDSRLLVSA 73
           R+  K C G S     +A  D   ++  R    + R   GH   + A+H  TD+ LL S 
Sbjct: 168 REITKVCYGASCNGMFSASRDKTIKMWQRGNSHSIRDFIGHDMVVTAIHLNTDNTLLCSG 347

Query: 74  SQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFVACGGLDNICSIYSLKTREGNV 133
           S+D  + IWD  T   +    +  + V    + P  + +   G D    IY  +T    +
Sbjct: 348 SRDNTVRIWDVETGACLRQNNIPQNLVTDVKWLPGSHLIIQAGEDKEVRIYDSRT----L 515

Query: 134 RVSRELPGHTGYLSCCRFLDDNQI-ITSS---GDTTC--ALWDIETGQQTVGFAGHSGDV 187
            + R           C    D Q  +T S   G   C   LW +  G     F GH   +
Sbjct: 516 GIVRSFTKKQYIQMSCDVTADGQFCLTCSNGFGGNGCEATLWQLSDGSIQNEFKGHREAI 695

Query: 188 MSLSLAPDGR--TFVSGAC-DASIKLWDV--RDSMCRQTFIGHESDINAVAF 234
            +    P  +  T ++ A  D S+++W++  ++ +C Q F G     + +A+
Sbjct: 696 EACLFLPSNQDMTLIATASRDCSVRVWNMFTKECVCEQNFEGTGPLTSMIAY 851

 Score = 47.0 bits (110), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 33/143 (23%), Positives = 64/143 (44%), Gaps = 1/143 (0%)
 Frame = +3

Query: 158 ITSSGDTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSM 217
           ++ S D +  L+D + G+    + GH  ++  +          S + D +IK+W   +S 
Sbjct: 87  LSGSKDKSVVLYDYQNGRLEDRWTGHDREITKVCYGASCNGMFSASRDKTIKMWQRGNSH 266

Query: 218 CRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRADQELLMYSHDNIICG-ITSV 276
             + FIGH+  + A+    +     +GS D T R++D+     L     +NI    +T V
Sbjct: 267 SIRDFIGHDMVVTAIHLNTDNTLLCSGSRDNTVRIWDVETGACL---RQNNIPQNLVTDV 437

Query: 277 AFSRSGRLLLAGYDDFNCNIWDA 299
            +     L++   +D    I+D+
Sbjct: 438 KWLPGSHLIIQAGEDKEVRIYDS 506

 Score = 45.1 bits (105), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 49/215 (22%), Positives = 90/215 (41%), Gaps = 12/215 (5%)
 Frame = +3

Query: 53  GHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFV 112
           GH  +I  + +G     + SAS+D  + +W    ++ +    +    V+T  +  + N +
Sbjct: 159 GHDREITKVCYGASCNGMFSASRDKTIKMWQRGNSHSIRDF-IGHDMVVTAIHLNTDNTL 335

Query: 113 AC-GGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQIITSSG-DTTCALWD 170
            C G  DN   I+ ++T  G       +P +   ++  ++L  + +I  +G D    ++D
Sbjct: 336 LCSGSRDNTVRIWDVET--GACLRQNNIPQN--LVTDVKWLPGSHLIIQAGEDKEVRIYD 503

Query: 171 IETGQQTVGFAGHSGDVMSLSLAPDGR-------TFVSGACDASIKLWDVRDSMCRQTFI 223
             T      F       MS  +  DG+        F    C+A+  LW + D   +  F 
Sbjct: 504 SRTLGIVRSFTKKQYIQMSCDVTADGQFCLTCSNGFGGNGCEAT--LWQLSDGSIQNEFK 677

Query: 224 GHESDINAVAFFPNGYAFT---TGSDDATCRLFDL 255
           GH   I A  F P+    T   T S D + R++++
Sbjct: 678 GHREAIEACLFLPSNQDMTLIATASRDCSVRVWNM 782
>21105
          Length = 650

 Score = 53.5 bits (127), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 30/100 (30%), Positives = 46/100 (46%), Gaps = 4/100 (4%)
 Frame = +1

Query: 158 ITSSGDTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSM 217
           IT+  D     +D  TG+       H   V SL++ P+G   +SG+ D SI+LW++    
Sbjct: 112 ITAHEDRHIRFFDNNTGKLIHAMVAHLDSVTSLAVDPNGLYLLSGSHDCSIRLWNLDSKT 291

Query: 218 CRQTFIGH----ESDINAVAFFPNGYAFTTGSDDATCRLF 253
           C Q    H    +  I+ VAF P      +   DA  ++F
Sbjct: 292 CVQEITSHRKKFDESIHDVAFHPQKPYIASAGADALAKVF 411
>01249
          Length = 1743

 Score = 52.8 bits (125), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 49/200 (24%), Positives = 80/200 (40%), Gaps = 27/200 (13%)
 Frame = -1

Query: 168  LWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWD-----------VRDS 216
            +W++ TG   VG      +   +    DG  FV       + +WD            R  
Sbjct: 1416 IWEM-TGGSLVGLLSDFNEATKIQFTDDGSQFVVATSSGHLNIWDFARVVTTTSQRARGL 1240

Query: 217  MCRQTFIGHESDINAVAFFPNGYA--FTTGSDDATCRLFDLRADQELLMYSHDNIICGIT 274
               +T   H   I  +     G A    + S D TC+L+D+ +   L    ++    G+ 
Sbjct: 1239 KPGRTINAHSEPITGLHVGCGGPAARVASSSSDGTCKLWDMLSGALLRTMVYET---GVG 1069

Query: 275  SVAFSRSGRLLLAGYD--DFNCN----------IWDAMKGDRAG--VLAGHDNRVSCLGV 320
             +   +    LLAG D  D  C+          ++ +    +AG  VL GH + V+CL  
Sbjct: 1068 CLIMDKQEHFLLAGLDNGDILCSPLFGQISQSEVFVSKHTTKAGERVLQGHSDAVTCLAF 889

Query: 321  TDDGMAVATGSWDSFLKIWN 340
            + DG  +A+GS +  + IWN
Sbjct: 888  SSDGQRLASGSQNGKVIIWN 829

 Score = 34.7 bits (78), Expect = 0.063,   Method: Compositional matrix adjust.
 Identities = 14/36 (38%), Positives = 23/36 (63%)
 Frame = -1

Query: 48  RRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWD 83
            R L+GH   +  + + +D + L S SQ+GK+IIW+
Sbjct: 936 ERVLQGHSDAVTCLAFSSDGQRLASGSQNGKVIIWN 829

 Score = 34.3 bits (77), Expect = 0.077,   Method: Compositional matrix adjust.
 Identities = 42/181 (23%), Positives = 73/181 (40%), Gaps = 27/181 (14%)
 Frame = -1

Query: 150  RFLDD-NQIITSSGDTTCALWDIE-----TGQQTVGFA------GHSGDVMSLSLA---P 194
            +F DD +Q + ++      +WD       T Q+  G         HS  +  L +    P
Sbjct: 1350 QFTDDGSQFVVATSSGHLNIWDFARVVTTTSQRARGLKPGRTINAHSEPITGLHVGCGGP 1171

Query: 195  DGRTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTTGSD--DATCR- 251
              R   S + D + KLWD+      +T + +E+ +  +      +    G D  D  C  
Sbjct: 1170 AARV-ASSSSDGTCKLWDMLSGALLRTMV-YETGVGCLIMDKQEHFLLAGLDNGDILCSP 997

Query: 252  LFDLRADQELLMYSH-----DNIICG----ITSVAFSRSGRLLLAGYDDFNCNIWDAMKG 302
            LF   +  E+ +  H     + ++ G    +T +AFS  G+ L +G  +    IW+   G
Sbjct: 996  LFGQISQSEVFVSKHTTKAGERVLQGHSDAVTCLAFSSDGQRLASGSQNGKVIIWNMESG 817

Query: 303  D 303
            D
Sbjct: 816  D 814

 Score = 29.3 bits (64), Expect = 2.1,   Method: Compositional matrix adjust.
 Identities = 36/175 (20%), Positives = 64/175 (36%), Gaps = 5/175 (2%)
 Frame = -1

Query: 45   MRTRRTLRGHLAKIYAMHWGT--DSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMT 102
            ++  RT+  H   I  +H G    +  + S+S DG   +WD  +   +  +   +   + 
Sbjct: 1242 LKPGRTINAHSEPITGLHVGCGGPAARVASSSSDGTCKLWDMLSGALLRTMVYETG--VG 1069

Query: 103  CAYAPSGNFVACGGLDN---ICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQIIT 159
            C            GLDN   +CS    +  +  V VS+    HT               T
Sbjct: 1068 CLIMDKQEHFLLAGLDNGDILCSPLFGQISQSEVFVSK----HT---------------T 946

Query: 160  SSGDTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVR 214
             +G+                  GHS  V  L+ + DG+   SG+ +  + +W++ 
Sbjct: 945  KAGERV--------------LQGHSDAVTCLAFSSDGQRLASGSQNGKVIIWNME 823
>37180
          Length = 681

 Score = 49.7 bits (117), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 26/76 (34%), Positives = 41/76 (53%), Gaps = 1/76 (1%)
 Frame = +1

Query: 182 GHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDS-MCRQTFIGHESDINAVAFFPNGYA 240
           GH  ++  +   P  R  V+ + D + +LWD RDS +    F GH   + + A F +G  
Sbjct: 13  GHDQELSDVHAHPTQRLVVTSSKDMTFRLWDFRDSALLVNVFQGHTQPVTS-AVFASGDK 189

Query: 241 FTTGSDDATCRLFDLR 256
             +GSDD T R++D+R
Sbjct: 190 VVSGSDDRTVRVWDMR 237

 Score = 42.4 bits (98), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 32/108 (29%), Positives = 47/108 (43%), Gaps = 1/108 (0%)
 Frame = +1

Query: 157 IITSSGDTTCALWDIETGQQTVG-FAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRD 215
           ++TSS D T  LWD       V  F GH+  V S   A  G   VSG+ D ++++WD+R+
Sbjct: 64  VVTSSKDMTFRLWDFRDSALLVNVFQGHTQPVTSAVFA-SGDKVVSGSDDRTVRVWDMRN 240

Query: 216 SMCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRADQELLM 263
                  I  +S +N    F    A T      T  +F      E ++
Sbjct: 241 MRSPIATIRTDSAVNRFV*FQYRPASTQSPFPMTTAMFGXXTSMECVL 384

 Score = 29.6 bits (65), Expect = 1.7,   Method: Compositional matrix adjust.
 Identities = 18/77 (23%), Positives = 36/77 (46%)
 Frame = +1

Query: 51  LRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGN 110
           L GH  ++  +H     RL+V++S+D    +WD   +  +  +    +  +T A   SG+
Sbjct: 7   LNGHDQELSDVHAHPTQRLVVTSSKDMTFRLWDFRDSALLVNVFQGHTQPVTSAVFASGD 186

Query: 111 FVACGGLDNICSIYSLK 127
            V  G  D    ++ ++
Sbjct: 187 KVVSGSDDRTVRVWDMR 237
>03387
          Length = 1891

 Score = 48.9 bits (115), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 44/159 (27%), Positives = 74/159 (46%), Gaps = 13/159 (8%)
 Frame = +1

Query: 156 QIITSSGDTTCALWDIETGQQT-------VGFAGHSGDVMSLSLAPDGRT-FVSGACDAS 207
            ++++S D T  LWDI + Q+          F GH+  V  ++      + F S A D  
Sbjct: 406 HLLSASDDHTICLWDINSTQRESRVVDAHTIFTGHTSVVEDVAWHLLHESLFGSVADDQK 585

Query: 208 IKLWDVRD---SMCRQTFIGHESDINAVAFFP-NGYAFTTGSDDATCRLFDLRADQELLM 263
           + +WD R    S        H +++N ++F P + +   TGS D T  L+DLR + +L +
Sbjct: 586 LMIWDTRSNTTSKPSHVVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLR-NLKLKL 762

Query: 264 YSHDNIICGITSVAFSRSGRLLLAGY-DDFNCNIWDAMK 301
           +S ++    I  V +S     +LA    D   ++WD  K
Sbjct: 763 HSFESHKDEIFQVQWSPHNETILASSGTDRRLHVWDLSK 879

 Score = 46.6 bits (109), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 58/254 (22%), Positives = 99/254 (38%), Gaps = 14/254 (5%)
 Frame = +1

Query: 31  TQITAGLDPVGRIQMRTRRTLRGHLAKIYAMHWGTD-SRLLVSASQDGKLIIWDSYTTNK 89
           T+  +  DP G      R  L+GH  + Y + W  + +  L+SAS D  + +WD  +T +
Sbjct: 295 TKHPSKPDPSGECIPELR--LKGHQKEGYGLSWNPNLNGHLLSASDDHTICLWDINSTQR 468

Query: 90  ------VHAIPLRSSWVMTCAYAPSGNFVACGGLDNICSIYSLKTREGNV-RVSRELPGH 142
                  H I    + V+        +    G + +   +    TR     + S  +  H
Sbjct: 469 ESRVVDAHTIFTGHTSVVEDVAWHLLHESLFGSVADDQKLMIWDTRSNTTSKPSHVVDAH 648

Query: 143 TGYLSCCRFLDDNQII--TSSGDTTCALWDIETGQQTV-GFAGHSGDVMSLSLAPDGRTF 199
           T  ++C  F   ++ I  T S D T ALWD+   +  +  F  H  ++  +  +P   T 
Sbjct: 649 TAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPHNETI 828

Query: 200 V-SGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRAD 258
           + S   D  + +WD+       + IG E         P    F  G   A    F    +
Sbjct: 829 LASSGTDRRLHVWDL-------SKIGEEQLPEDAEDGPPELLFIHGGHTAKISDFSWNPN 987

Query: 259 QELLM--YSHDNII 270
           +  ++   S DNI+
Sbjct: 988 EPWIVCSVSEDNIM 1029
>14500
          Length = 1238

 Score = 34.3 bits (77), Expect(2) = 3e-06,   Method: Compositional matrix adjust.
 Identities = 18/59 (30%), Positives = 30/59 (50%), Gaps = 5/59 (8%)
 Frame = +2

Query: 180 FAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVR-----DSMCRQTFIGHESDINAVA 233
            +GHS +V  L  +PDG+   SGA D  + +W  +      +    TF  H++ + A+A
Sbjct: 47  LSGHSQEVCGLRWSPDGKYLASGANDNLLCVWPAQVTGGNSTQPLHTFSQHQAAVKALA 223

 Score = 33.9 bits (76), Expect(2) = 3e-06,   Method: Compositional matrix adjust.
 Identities = 18/70 (25%), Positives = 33/70 (47%), Gaps = 2/70 (2%)
 Frame = +3

Query: 273 ITSVAFSRSGRLLLA--GYDDFNCNIWDAMKGDRAGVLAGHDNRVSCLGVTDDGMAVATG 330
           + ++ +S+  R L++  G+      IW      R   L GH  RV  + ++ DG  V + 
Sbjct: 342 VCALLWSKEHRELISSHGFAQNQLIIWKYPAMSRVAELTGHTARVLHMAMSPDGETVVSA 521

Query: 331 SWDSFLKIWN 340
           + D  L++W 
Sbjct: 522 AADETLRLWK 551

 Score = 42.4 bits (98), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 17/62 (27%), Positives = 32/62 (51%), Gaps = 2/62 (3%)
 Frame = +3

Query: 153 DDNQIITSSG--DTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKL 210
           +  ++I+S G       +W      +     GH+  V+ ++++PDG T VS A D +++L
Sbjct: 366 EHRELISSHGFAQNQLIIWKYPAMSRVAELTGHTARVLHMAMSPDGETVVSAAADETLRL 545

Query: 211 WD 212
           W 
Sbjct: 546 WK 551

 Score = 33.5 bits (75), Expect = 0.13,   Method: Compositional matrix adjust.
 Identities = 16/57 (28%), Positives = 25/57 (43%)
 Frame = +2

Query: 41 GRIQMRTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRS 97
          GR+      TL GH  ++  + W  D + L S + D  L +W +  T      PL +
Sbjct: 17 GRVADHHVGTLSGHSQEVCGLRWSPDGKYLASGANDNLLCVWPAQVTGGNSTQPLHT 187

 Score = 30.4 bits (67), Expect = 1.0,   Method: Compositional matrix adjust.
 Identities = 15/44 (34%), Positives = 22/44 (50%)
 Frame = +3

Query: 51  LRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIP 94
           L GH A++  M    D   +VSA+ D  L +W  +T +K    P
Sbjct: 453 LTGHTARVLHMAMSPDGETVVSAAADETLRLWKCFTVDKEKKRP 584

 Score = 24.3 bits (51), Expect(2) = 1.7,   Method: Compositional matrix adjust.
 Identities = 22/103 (21%), Positives = 38/103 (36%), Gaps = 3/103 (2%)
 Frame = +3

Query: 161 SGDTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVS--GACDASIKLWDVRDSMC 218
           + D     W+  TG         S  V +L  + + R  +S  G     + +W       
Sbjct: 267 TADRHIHFWNCNTGTNLSSVDTKS-QVCALLWSKEHRELISSHGFAQNQLIIWKYPAMSR 443

Query: 219 RQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFD-LRADQE 260
                GH + +  +A  P+G    + + D T RL+     D+E
Sbjct: 444 VAELTGHTARVLHMAMSPDGETVVSAAADETLRLWKCFTVDKE 572

 Score = 23.9 bits (50), Expect(2) = 1.7,   Method: Compositional matrix adjust.
 Identities = 8/28 (28%), Positives = 16/28 (57%)
 Frame = +2

Query: 105 YAPSGNFVACGGLDNICSIYSLKTREGN 132
           ++P G ++A G  DN+  ++  +   GN
Sbjct: 83  WSPDGKYLASGANDNLLCVWPAQVTGGN 166

 Score = 28.5 bits (62), Expect = 4.4,   Method: Compositional matrix adjust.
 Identities = 16/71 (22%), Positives = 33/71 (46%), Gaps = 2/71 (2%)
 Frame = +3

Query: 56  AKIYAMHWGTDSRLLVSAS--QDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFVA 113
           +++ A+ W  + R L+S+      +LIIW     ++V  +   ++ V+  A +P G  V 
Sbjct: 336 SQVCALLWSKEHRELISSHGFAQNQLIIWKYPAMSRVAELTGHTARVLHMAMSPDGETVV 515

Query: 114 CGGLDNICSIY 124
               D    ++
Sbjct: 516 SAAADETLRLW 548
>12574
          Length = 521

 Score = 48.9 bits (115), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 29/119 (24%), Positives = 52/119 (43%), Gaps = 1/119 (0%)
 Frame = +3

Query: 128 TREGNVRVSRELPGHTGYLSCCRFLDDNQ-IITSSGDTTCALWDIETGQQTVGFAGHSGD 186
           T++    +   L GHT  LS  +F  +   + +SS D    +W    G+     AGH   
Sbjct: 141 TQKPTYTLKFTLAGHTKALSAVKFSPNGDWLASSSADKLIKIWGAYDGKFEKTIAGHKLG 320

Query: 187 VMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTTGS 245
           +  ++ + D +   S + D ++K+W+     C +T  GH + +    F P      +GS
Sbjct: 321 LSDVAWSSDSKLLCSASDDKTLKIWEFSTGKCMKTLKGHSNYVFCCNFNPQSNLIVSGS 497

 Score = 47.8 bits (112), Expect = 6e-06,   Method: Compositional matrix adjust.
 Identities = 31/116 (26%), Positives = 51/116 (43%), Gaps = 3/116 (2%)
 Frame = +3

Query: 219 RQTFIGHESDINAVAFFPNGYAFTTGSDDATCRL---FDLRADQELLMYSHDNIICGITS 275
           + T  GH   ++AV F PNG    + S D   ++   +D + ++ +  +       G++ 
Sbjct: 165 KFTLAGHTKALSAVKFSPNGDWLASSSADKLIKIWGAYDGKFEKTIAGHK-----LGLSD 329

Query: 276 VAFSRSGRLLLAGYDDFNCNIWDAMKGDRAGVLAGHDNRVSCLGVTDDGMAVATGS 331
           VA+S   +LL +  DD    IW+   G     L GH N V C         + +GS
Sbjct: 330 VAWSSDSKLLCSASDDKTLKIWEFSTGKCMKTLKGHSNYVFCCNFNPQSNLIVSGS 497

 Score = 47.0 bits (110), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 24/77 (31%), Positives = 38/77 (49%)
 Frame = +3

Query: 41  GRIQMRTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWV 100
           G    +  +T+ GH   +  + W +DS+LL SAS D  L IW+  T   +  +   S++V
Sbjct: 270 GAYDGKFEKTIAGHKLGLSDVAWSSDSKLLCSASDDKTLKIWEFSTGKCMKTLKGHSNYV 449

Query: 101 MTCAYAPSGNFVACGGL 117
             C + P  N +  G L
Sbjct: 450 FCCNFNPQSNLIVSGSL 500

 Score = 43.5 bits (101), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 22/92 (23%), Positives = 45/92 (48%), Gaps = 1/92 (1%)
 Frame = +3

Query: 180 FAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGY 239
            AGH+  + ++  +P+G    S + D  IK+W   D    +T  GH+  ++ VA+  +  
Sbjct: 174 LAGHTKALSAVKFSPNGDWLASSSADKLIKIWGAYDGKFEKTIAGHKLGLSDVAWSSDSK 353

Query: 240 AFTTGSDDATCRLFDLRADQEL-LMYSHDNII 270
              + SDD T ++++    + +  +  H N +
Sbjct: 354 LLCSASDDKTLKIWEFSTGKCMKTLKGHSNYV 449

 Score = 37.7 bits (86), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 26/113 (23%), Positives = 45/113 (39%)
 Frame = +3

Query: 48  RRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAP 107
           + TL GH   + A+ +  +   L S+S D  + IW +Y       I      +   A++ 
Sbjct: 165 KFTLAGHTKALSAVKFSPNGDWLASSSADKLIKIWGAYDGKFEKTIAGHKLGLSDVAWSS 344

Query: 108 SGNFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQIITS 160
               +     D    I+   T     +  + L GH+ Y+ CC F   + +I S
Sbjct: 345 DSKLLCSASDDKTLKIWEFSTG----KCMKTLKGHSNYVFCCNFNPQSNLIVS 491

 Score = 33.1 bits (74), Expect = 0.17,   Method: Compositional matrix adjust.
 Identities = 21/69 (30%), Positives = 32/69 (46%)
 Frame = +3

Query: 272 GITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDRAGVLAGHDNRVSCLGVTDDGMAVATGS 331
            +++V FS +G  L +   D    IW A  G     +AGH   +S +  + D   + + S
Sbjct: 192 ALSAVKFSPNGDWLASSSADKLIKIWGAYDGKFEKTIAGHKLGLSDVAWSSDSKLLCSAS 371

Query: 332 WDSFLKIWN 340
            D  LKIW 
Sbjct: 372 DDKTLKIWE 398
>10162
          Length = 1629

 Score = 48.5 bits (114), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 60/300 (20%), Positives = 111/300 (37%), Gaps = 19/300 (6%)
 Frame = +3

Query: 58  IYAMHWGTDSRLLVSASQDGKLIIWD--SYTTNKVHAIPLRSSWVMTCAYAPSGNFVACG 115
           I  + W   + +L++ +Q G++ +W   S   +K+  +       +     P+G +V  G
Sbjct: 36  ITWLQWHGGAHVLLAGTQGGEVWLWQVPSQDYSKMKMLQSHGQPSLCGKILPNGKYVCVG 215

Query: 116 GLDNICSIYSLKTR------EGNVRVSRELPGHTGYLSCCRFLDDNQIITSSGDTTCALW 169
             D +  ++ LKT       + +V    E+P             + +    +    C   
Sbjct: 216 YSDGVVKLWDLKTGTAVHTWQHSVMPEEEMPERNSSDEEDGEEVEVEREEDTVAILC--- 386

Query: 170 DIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTF------- 222
                               +  + D    +SG  DA+ K+++V        F       
Sbjct: 387 --------------------VDCSADNALIMSGCADATAKVFNVSSGKLXSAFNCAASQD 506

Query: 223 -IGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRADQELLMYSHDNIICGITSVAFSRS 281
               ++ + +VAF P      T ++  + +++DL        + H   +C +    +S S
Sbjct: 507 SQDKDNSVESVAFCPVSPYAATATNSGSVQVWDLPTSVARHSFQHPEGVCKLQ---WSSS 677

Query: 282 GRLLLAGYDDFNCNIWDAMKGDRAGVLAGHDNRVSCL---GVTDDGMAVATGSWDSFLKI 338
             LL     D    +WDA  G    VL GH  R SC+    VT DG  + +GS D   ++
Sbjct: 678 TALLYTACLDGVMRVWDARSGASKAVLTGH-ARNSCILDFDVTRDGTCLVSGSEDGTARV 854
>19498
          Length = 903

 Score = 48.5 bits (114), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 34/139 (24%), Positives = 60/139 (43%), Gaps = 19/139 (13%)
 Frame = -1

Query: 134 RVSRELPGHTGYLSCCRFLDDNQIITSSGD-TTCALWDIETG-----------------Q 175
           RV  ++  H G ++C R+ ++ + + S GD     +W I  G                 +
Sbjct: 813 RVLCQMDSHLGCVNCVRWSENGKFLASGGDDKLIMIWQISRGFGSGKSFGSNVTILEHWR 634

Query: 176 QTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWD-VRDSMCRQTFIGHESDINAVAF 234
                 GH+GDV+ L+ +P      S + D +I +W+ ++ S       GH   +  V +
Sbjct: 633 SVATLRGHAGDVLDLAWSPQDLWLASCSVDNTIVVWNALKFSEQVAVIRGHAGMVKGVTW 454

Query: 235 FPNGYAFTTGSDDATCRLF 253
            P G    + SDD T R++
Sbjct: 453 DPVGRYLASQSDDKTLRVW 397

 Score = 39.3 bits (90), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 32/126 (25%), Positives = 56/126 (44%), Gaps = 15/126 (11%)
 Frame = -1

Query: 105 YAPSGNFVACGGLDNICSIYSL-------KTREGNVRVSRE------LPGHTG-YLSCCR 150
           ++ +G F+A GG D +  I+ +       K+   NV +         L GH G  L    
Sbjct: 762 WSENGKFLASGGDDKLIMIWQISRGFGSGKSFGSNVTILEHWRSVATLRGHAGDVLDLAW 583

Query: 151 FLDDNQIITSSGDTTCALWD-IETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIK 209
              D  + + S D T  +W+ ++  +Q     GH+G V  ++  P GR   S + D +++
Sbjct: 582 SPQDLWLASCSVDNTIVVWNALKFSEQVAVIRGHAGMVKGVTWDPVGRYLASQSDDKTLR 403

Query: 210 LWDVRD 215
           +W   D
Sbjct: 402 VWRTSD 385

 Score = 34.3 bits (77), Expect = 0.083,   Method: Compositional matrix adjust.
 Identities = 31/157 (19%), Positives = 60/157 (38%), Gaps = 8/157 (5%)
 Frame = -1

Query: 46  RTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYT-TNKVHAIPLRSSWVMTCA 104
           R+  TLRGH   +  + W      L S S D  +++W++   + +V  I   +  V    
Sbjct: 636 RSVATLRGHAGDVLDLAWSPQDLWLASCSVDNTIVVWNALKFSEQVAVIRGHAGMVKGVT 457

Query: 105 YAPSGNFVACGGLDNICSIYSLKTREGNVRVS---RELPGHTGYLSCCRFLDDNQIITS- 160
           + P G ++A    D    ++     +    V    +E  G T  L      D N ++++ 
Sbjct: 456 WDPVGRYLASQSDDKTLRVWRTSDWKEETCVKSCFKECGGTTHVLRLNWSPDGNHVVSAH 277

Query: 161 ---SGDTTCALWDIETGQQTVGFAGHSGDVMSLSLAP 194
              +   T  + +      ++ F GH   +  +   P
Sbjct: 276 AMNNAXPTAQIIERNGWGTSLDFVGHRKAITVVRFNP 166
>16199
          Length = 694

 Score = 39.3 bits (90), Expect(2) = 3e-05,   Method: Compositional matrix adjust.
 Identities = 14/41 (34%), Positives = 25/41 (60%)
 Frame = +2

Query: 194 PDGRTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAF 234
           PDG  F +G  D+ IK+WD+++      F GH+  + +++F
Sbjct: 101 PDGLIFATGTEDSVIKIWDLKERANVANFQGHQGPVTSISF 223

 Score = 25.8 bits (55), Expect(2) = 3e-05,   Method: Compositional matrix adjust.
 Identities = 25/106 (23%), Positives = 46/106 (43%), Gaps = 3/106 (2%)
 Frame = +1

Query: 237 NGYAFTTGSDDATCRLFDLRADQELLMYSHDNIICGITSVAFSRSGRLL-LAGYD--DFN 293
           NGY   T ++D+  +L+DLR  +        +    + ++ F +SG  L +AG D   + 
Sbjct: 229 NGYYLATSAEDSVVKLWDLRKLKNFKTLQLGDKY-EVKALCFDQSGTYLAVAGSDVRVYL 405

Query: 294 CNIWDAMKGDRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIW 339
           C  W+ +      V   H    + +    +   +A+ S D  LK +
Sbjct: 406 CKQWNEL-----AVFNDHTATATGVRFGTNANFIASASMDRSLKFF 528

 Score = 33.9 bits (76), Expect = 0.086,   Method: Compositional matrix adjust.
 Identities = 16/49 (32%), Positives = 25/49 (51%), Gaps = 1/49 (2%)
 Frame = +2

Query: 146 LSCCRFLDDNQII-TSSGDTTCALWDIETGQQTVGFAGHSGDVMSLSLA 193
           L+C +F  D  I  T + D+   +WD++       F GH G V S+S +
Sbjct: 80  LTCAQFHPDGLIFATGTEDSVIKIWDLKERANVANFQGHQGPVTSISFS 226

 Score = 28.1 bits (61), Expect = 5.7,   Method: Compositional matrix adjust.
 Identities = 11/26 (42%), Positives = 17/26 (65%)
 Frame = +2

Query: 315 VSCLGVTDDGMAVATGSWDSFLKIWN 340
           ++C     DG+  ATG+ DS +KIW+
Sbjct: 80  LTCAQFHPDGLIFATGTEDSVIKIWD 157
>13278
          Length = 870

 Score = 45.1 bits (105), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 26/100 (26%), Positives = 47/100 (47%)
 Frame = +1

Query: 157 IITSSGDTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDS 216
           + ++S D+T  LW++E G        H   V S++ +PDG+   SG+ D  + +W+V+  
Sbjct: 121 LASASFDSTVRLWEVERGLCLHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNVQTG 300

Query: 217 MCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFDLR 256
               ++ G    I  V +   G      + D +  + DLR
Sbjct: 301 SLVHSYKG-TGGIFEVCWNHRGDKVGASASDGSVFVLDLR 417

 Score = 34.3 bits (77), Expect = 0.081,   Method: Compositional matrix adjust.
 Identities = 22/81 (27%), Positives = 39/81 (48%), Gaps = 9/81 (11%)
 Frame = +1

Query: 57  KIYAMHW-----GTD----SRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAP 107
           +IY + W     GT     S +L SAS D  + +W+      +H +      V + A++P
Sbjct: 55  EIYTIKWSPTGPGTSNPNTSLILASASFDSTVRLWEVERGLCLHTLTKHQEPVYSVAFSP 234

Query: 108 SGNFVACGGLDNICSIYSLKT 128
            G ++A G  D    I++++T
Sbjct: 235 DGKYLASGSFDKCVHIWNVQT 297

 Score = 29.6 bits (65), Expect = 2.0,   Method: Compositional matrix adjust.
 Identities = 23/102 (22%), Positives = 43/102 (42%), Gaps = 9/102 (8%)
 Frame = +1

Query: 210 LWDVRDSMCRQTFIGHESDINAVAFFPNG---------YAFTTGSDDATCRLFDLRADQE 260
           +W +    C         +I  + + P G             + S D+T RL+++  ++ 
Sbjct: 1   IWSMGKDSCIHDLQLTTKEIYTIKWSPTGPGTSNPNTSLILASASFDSTVRLWEV--ERG 174

Query: 261 LLMYSHDNIICGITSVAFSRSGRLLLAGYDDFNCNIWDAMKG 302
           L +++       + SVAFS  G+ L +G  D   +IW+   G
Sbjct: 175 LCLHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNVQTG 300

 Score = 28.9 bits (63), Expect = 2.9,   Method: Compositional matrix adjust.
 Identities = 19/70 (27%), Positives = 33/70 (47%), Gaps = 4/70 (5%)
 Frame = +1

Query: 27  DSTLTQITAGLDPVGRIQMRTR----RTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIW 82
           +++L   +A  D   R+    R     TL  H   +Y++ +  D + L S S D  + IW
Sbjct: 106 NTSLILASASFDSTVRLWEVERGLCLHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIW 285

Query: 83  DSYTTNKVHA 92
           +  T + VH+
Sbjct: 286 NVQTGSLVHS 315
>31384
          Length = 474

 Score = 44.3 bits (103), Expect = 7e-05,   Method: Compositional matrix adjust.
 Identities = 23/81 (28%), Positives = 42/81 (51%), Gaps = 6/81 (7%)
 Frame = -1

Query: 146 LSCCRF----LDDNQIITSSGDTTCALWDIETGQQTVGFAG--HSGDVMSLSLAPDGRTF 199
           +SC +F    L    +I+ S D   + W+++   QT+  A   H+G V+ +  + DG   
Sbjct: 267 VSCLKFSPGALPSTFLISGSWDNKVSCWEVQQSGQTIPKAQQTHTGPVLDVDWSDDGTKV 88

Query: 200 VSGACDASIKLWDVRDSMCRQ 220
            + +CD + K+WD+  + C Q
Sbjct: 87  FTASCDKTAKVWDLNSNQCMQ 25
>29912
          Length = 510

 Score = 43.5 bits (101), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 35/146 (23%), Positives = 64/146 (43%), Gaps = 8/146 (5%)
 Frame = +3

Query: 99  WVMTCAYAPSGNFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQII 158
           ++   ++   GN++A G       ++ +  +    +  R + GH   +     L  N  I
Sbjct: 15  YIGAVSWIKEGNYLALGTSTGEVQVWDVTQQ----KKLRTMAGHAARVGS---LSWNSFI 173

Query: 159 TSSGDTTCALW--DIETGQQTVG-FAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVR- 214
            SSG  +  +   D+      VG  +GHS +V  L  +PDG+   SGA D  + +W  + 
Sbjct: 174 VSSGSRSGNIHHHDVRVADHHVGTLSGHSQEVCGLRWSPDGKYLASGANDNLLCVWPAQV 353

Query: 215 ----DSMCRQTFIGHESDINAVAFFP 236
                +    TF  H++ + A+A+ P
Sbjct: 354 TGGNSTQPLHTFSQHQAAVKALAWCP 431

 Score = 32.0 bits (71), Expect = 0.37,   Method: Compositional matrix adjust.
 Identities = 27/109 (24%), Positives = 52/109 (47%), Gaps = 6/109 (5%)
 Frame = +3

Query: 145 YLSCCRFLDDNQII---TSSGDTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFV- 200
           Y+    ++ +   +   TS+G+    +WD+   ++    AGH+  V SLS      +F+ 
Sbjct: 15  YIGAVSWIKEGNYLALGTSTGEVQ--VWDVTQQKKLRTMAGHAARVGSLSW----NSFIV 176

Query: 201 -SGACDASIKLWDVRDS-MCRQTFIGHESDINAVAFFPNGYAFTTGSDD 247
            SG+   +I   DVR +     T  GH  ++  + + P+G    +G++D
Sbjct: 177 SSGSRSGNIHHHDVRVADHHVGTLSGHSQEVCGLRWSPDGKYLASGAND 323

 Score = 31.6 bits (70), Expect = 0.45,   Method: Compositional matrix adjust.
 Identities = 20/75 (26%), Positives = 33/75 (44%), Gaps = 6/75 (8%)
 Frame = +3

Query: 50  TLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSY-----TTNKVHAIPLRSSWVMTCA 104
           TL GH  ++  + W  D + L S + D  L +W +      +T  +H      + V   A
Sbjct: 243 TLSGHSQEVCGLRWSPDGKYLASGANDNLLCVWPAQVTGGNSTQPLHTFSQHQAAVKALA 422

Query: 105 YAP-SGNFVACGGLD 118
           + P   + +A GG D
Sbjct: 423 WCPWQPSXLASGGGD 467

 Score = 30.0 bits (66), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 17/64 (26%), Positives = 27/64 (42%)
 Frame = +3

Query: 273 ITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDRAGVLAGHDNRVSCLGVTDDGMAVATGSW 332
           I +V++ + G  L  G       +WD  +  +   +AGH  RV  L            SW
Sbjct: 18  IGAVSWIKEGNYLALGTSTGEVQVWDVTQQKKLRTMAGHAARVGSL------------SW 161

Query: 333 DSFL 336
           +SF+
Sbjct: 162 NSFI 173
>01462
          Length = 995

 Score = 43.1 bits (100), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 18/61 (29%), Positives = 32/61 (52%)
 Frame = +2

Query: 156 QIITSSGDTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRD 215
           ++   +GD    +WDIE GQ      GH   +  + +  D +  VS + D ++++WD+R 
Sbjct: 239 RLYAGAGDRKIHVWDIEAGQYLNAMEGHKDYIHKVVMKNDAQECVSASEDGTVRMWDIRS 418

Query: 216 S 216
           S
Sbjct: 419 S 421

 Score = 38.1 bits (87), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 18/64 (28%), Positives = 30/64 (46%)
 Frame = +2

Query: 197 RTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFDLR 256
           R   +GA D  I +WD+          GH+  I+ V    +     + S+D T R++D+R
Sbjct: 236 RRLYAGAGDRKIHVWDIEAGQYLNAMEGHKDYIHKVVMKNDAQECVSASEDGTVRMWDIR 415

Query: 257 ADQE 260
           +  E
Sbjct: 416 SSTE 427

 Score = 37.0 bits (84), Expect = 0.013,   Method: Compositional matrix adjust.
 Identities = 26/89 (29%), Positives = 42/89 (47%), Gaps = 11/89 (12%)
 Frame = +2

Query: 51  LRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWD-SYTTNKVHAI----------PLRSSW 99
           + GH   I+ +    D++  VSAS+DG + +WD   +T  VH +          PL   W
Sbjct: 311 MEGHKDYIHKVVMKNDAQECVSASEDGTVRMWDIRSSTETVHCLEPSKNELCSRPLLGKW 490

Query: 100 VMTCAYAPSGNFVACGGLDNICSIYSLKT 128
           +   A  P   ++ CGG   + S + L+T
Sbjct: 491 LRCLALDPEEGWLVCGGGPKL-SAWHLRT 574

 Score = 32.0 bits (71), Expect = 0.36,   Method: Compositional matrix adjust.
 Identities = 14/58 (24%), Positives = 27/58 (46%)
 Frame = +2

Query: 283 RLLLAGYDDFNCNIWDAMKGDRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
           R L AG  D   ++WD   G     + GH + +  + + +D     + S D  +++W+
Sbjct: 236 RRLYAGAGDRKIHVWDIEAGQYLNAMEGHKDYIHKVVMKNDAQECVSASEDGTVRMWD 409
>19863
          Length = 502

 Score = 43.1 bits (100), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 17/61 (27%), Positives = 36/61 (59%)
 Frame = +1

Query: 156 QIITSSGDTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRD 215
           Q+++ S D +  +WD+E G Q +   GH+G V  +  + D    +S + D ++++W++ +
Sbjct: 13  QLVSGSSDMSIVVWDVENGVQKLRLQGHAGWVNDVHFSQDQCWLLSCSNDNTVRIWNIEE 192

Query: 216 S 216
           S
Sbjct: 193 S 195

 Score = 41.6 bits (96), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 23/89 (25%), Positives = 42/89 (47%)
 Frame = +1

Query: 195 DGRTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFD 254
           DG   VSG+ D SI +WDV + + +    GH   +N V F  +     + S+D T R+++
Sbjct: 4   DGLQLVSGSSDMSIVVWDVENGVQKLRLQGHAGWVNDVHFSQDQCWLLSCSNDNTVRIWN 183

Query: 255 LRADQELLMYSHDNIICGITSVAFSRSGR 283
           +    ++ +        G+     S+ G+
Sbjct: 184 IEESDQIPIVMEHKRAQGLKVTKCSKCGK 270

 Score = 28.9 bits (63), Expect = 2.9,   Method: Compositional matrix adjust.
 Identities = 17/59 (28%), Positives = 30/59 (50%)
 Frame = +1

Query: 282 GRLLLAGYDDFNCNIWDAMKGDRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
           G  L++G  D +  +WD   G +   L GH   V+ +  + D   + + S D+ ++IWN
Sbjct: 7   GLQLVSGSSDMSIVVWDVENGVQKLRLQGHAGWVNDVHFSQDQCWLLSCSNDNTVRIWN 183
>11493
          Length = 535

 Score = 43.1 bits (100), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 25/110 (22%), Positives = 50/110 (45%), Gaps = 3/110 (2%)
 Frame = -2

Query: 145 YLSCCRFLDDNQIITSSGD-TTCALWDI--ETGQQTVGFAGHSGDVMSLSLAPDGRTFVS 201
           Y+   + L D + +   G+ +  ++WD+   T +        +    +L+++PD +   S
Sbjct: 333 YIRSVKLLPDGRTLIVGGEASNLSIWDLASPTPRIKAELTSAAPACYALAISPDSKVCFS 154

Query: 202 GACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCR 251
              D +I +WD+ + +  + F GH    + +   P+G    TG  D T R
Sbjct: 153 CCSDGNIAVWDLHNEILVRQFQGHTDGASCIDISPDGSRLWTGGLDNTVR 4

 Score = 42.7 bits (99), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 28/158 (17%), Positives = 65/158 (41%), Gaps = 5/158 (3%)
 Frame = -2

Query: 185 GDVMSLSLAPDGRTFVSGACDASIKLWDV-----RDSMCRQTFIGHESDINAVAFFPNGY 239
           G+V+      +   +V       +K+WD+     ++ + +   +  ++ I +V   P+G 
Sbjct: 477 GEVVCAVTISNPTKYVYTGGKGCVKVWDISQPGNKNPVSQLDCLQRDNYIRSVKLLPDGR 298

Query: 240 AFTTGSDDATCRLFDLRADQELLMYSHDNIICGITSVAFSRSGRLLLAGYDDFNCNIWDA 299
               G + +   ++DL +    +     +      ++A S   ++  +   D N  +WD 
Sbjct: 297 TLIVGGEASNLSIWDLASPTPRIKAELTSAAPACYALAISPDSKVCFSCCSDGNIAVWDL 118

Query: 300 MKGDRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLK 337
                     GH +  SC+ ++ DG  + TG  D+ ++
Sbjct: 117 HNEILVRQFQGHTDGASCIDISPDGSRLWTGGLDNTVR 4

 Score = 31.2 bits (69), Expect = 0.72,   Method: Compositional matrix adjust.
 Identities = 19/74 (25%), Positives = 30/74 (40%)
 Frame = -2

Query: 46  RTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAY 105
           R +  L       YA+    DS++  S   DG + +WD +    V      +        
Sbjct: 234 RIKAELTSAAPACYALAISPDSKVCFSCCSDGNIAVWDLHNEILVRQFQGHTDGASCIDI 55

Query: 106 APSGNFVACGGLDN 119
           +P G+ +  GGLDN
Sbjct: 54  SPDGSRLWTGGLDN 13
>01598
          Length = 1545

 Score = 43.1 bits (100), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 33/125 (26%), Positives = 59/125 (47%), Gaps = 15/125 (12%)
 Frame = +1

Query: 104  AYAPSGNFVACGGLDNICSIYSLKT----REGNVRVS------RELPGHTGYLSCCRFLD 153
            A +P  +++A  G D +  +  L +    REG+   S      REL GH+  ++   +  
Sbjct: 1153 AGSPCCHWLAAAGNDQVIHVVDLASVFAEREGDKETSLILTSLRELSGHSQRVTDMSWSP 1332

Query: 154  --DNQIITSSGDTTCALWDIETGQQTVGFAGHSGDVMSLS---LAPDGRTFVSGACDASI 208
              D ++++   D    +WD++ G     F GH G +++     L PD    ++G  DAS+
Sbjct: 1333 HHDARLVSVGYDAEAFVWDVQKGTALAQFKGHMGRLLTCQFSGLDPD--LVMTGGSDASV 1506

Query: 209  KLWDV 213
             +W V
Sbjct: 1507 HVWRV 1521

 Score = 40.4 bits (93), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 50/205 (24%), Positives = 79/205 (38%), Gaps = 9/205 (4%)
 Frame = +1

Query: 60  AMHW-GTDSRLLVSASQDGKLIIWD-SYTTNKVHAIPLRSSWVMTCAYAPSGNFVACGGL 117
           A+HW  ++   LVS+S  G L++W   YT  + +          T  Y P    V     
Sbjct: 241 AIHWLKSNPEQLVSSSSGGDLLLWSLRYTKGQAYQT------FQTSDYRPHMRPVF---- 390

Query: 118 DNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQIITSSGDTTCALWDIETGQQT 177
            NIC+                        + C F  D Q++         LWD+ET +  
Sbjct: 391 -NICA------------------SGPDSKTLCTFAQDRQVV---------LWDLETMEAV 486

Query: 178 VGFAGHSGDVMSLSLAP--DGRTFVSGACDASIKLWDVRDSM----CRQTFIGHESDINA 231
              A   G V  +  +P   GR  V G  D+ I+ W++ +          + G +S + A
Sbjct: 487 ASMATLGGHVYCVRTSPIDPGRVAV-GVGDSMIRTWNMSNKTNPYDVTTLWQGIKSKVTA 663

Query: 232 VAFFPNGYAFTT-GSDDATCRLFDL 255
           VA+ P    +   G+DD    +FD+
Sbjct: 664 VAWHPTKEGWLGFGTDDGRIGVFDV 738

 Score = 30.8 bits (68), Expect = 0.94,   Method: Compositional matrix adjust.
 Identities = 47/218 (21%), Positives = 78/218 (35%), Gaps = 27/218 (12%)
 Frame = +1

Query: 149  CRFLDDNQIITSSGDTTCALWDIETGQQTVGFAGHSG-DVMSLSLAPDGRTFVSGACDAS 207
            C+ L+ +  + S G+      DI      V      G     LS +PD      G  + S
Sbjct: 865  CKILEHSSAVLSRGEKKANAIDITQKIGAVNSDQVKGLKATELSWSPDQNAAAVGTDEGS 1044

Query: 208  IKLWDVRDSMCRQTFIGHESDINAVAFFPN-----------GYAFTTGSDDATCRLFDL- 255
            + +  ++D          +  IN V + P             +      +D    + DL 
Sbjct: 1045 VYVVTIQDLKIVAAIRTQQKLINCVRWHPRLTDQSPAGSPCCHWLAAAGNDQVIHVVDLA 1224

Query: 256  ------RADQEL-LMYSHDNIICG----ITSVAFS--RSGRLLLAGYDDFNCNIWDAMKG 302
                    D+E  L+ +    + G    +T +++S     RL+  GYD     +WD  KG
Sbjct: 1225 SVFAEREGDKETSLILTSLRELSGHSQRVTDMSWSPHHDARLVSVGYD-AEAFVWDVQKG 1401

Query: 303  DRAGVLAGHDNR-VSCLGVTDDGMAVATGSWDSFLKIW 339
                   GH  R ++C     D   V TG  D+ + +W
Sbjct: 1402 TALAQFKGHMGRLLTCQFSGLDPDLVMTGGSDASVHVW 1515
>12960
          Length = 550

 Score = 42.7 bits (99), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 28/112 (25%), Positives = 50/112 (44%)
 Frame = +2

Query: 187 VMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTTGSD 246
           V ++  + D R  ++   D S+KLW+    +  +T+IGH  ++       +     +G  
Sbjct: 182 VRAVRFSVDSRYCMTCGSDKSVKLWNPHRELFLKTYIGHGHEVLDAQGSGDNSQICSGGI 361

Query: 247 DATCRLFDLRADQELLMYSHDNIICGITSVAFSRSGRLLLAGYDDFNCNIWD 298
           D T  LFD+ + Q L  Y   +    +  V F+    ++L+G  D     WD
Sbjct: 362 DKTVVLFDVASGQALRKYR--DHAGTVNCVKFNEESTVILSGSLDNTVRAWD 511

 Score = 41.2 bits (95), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 18/62 (29%), Positives = 33/62 (53%)
 Frame = +2

Query: 153 DDNQIITSSGDTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWD 212
           D++QI +   D T  L+D+ +GQ    +  H+G V  +    +    +SG+ D +++ WD
Sbjct: 332 DNSQICSGGIDKTVVLFDVASGQALRKYRDHAGTVNCVKFNEESTVILSGSLDNTVRAWD 511

Query: 213 VR 214
            R
Sbjct: 512 TR 517
>18981
          Length = 407

 Score = 42.7 bits (99), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 36/111 (32%), Positives = 52/111 (46%)
 Frame = -2

Query: 152 LDDNQIITSSGDTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLW 211
           L DN II+++ D T  +W ++         GH+ DV  + +   GR  VSG+ D ++ +W
Sbjct: 394 LLDNMIISAATDRTLRVWCLKNTCLLHTLRGHNDDVECVCIY--GRRVVSGSWDKTLIVW 221

Query: 212 DVRDSMCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRADQELL 262
           +V          GH   I AV  F  G A  +GS D   R + L   Q LL
Sbjct: 220 EVDTGRPVHQLHGHTEAITAVQ-FDEGKAV-SGSADGDVRTWALDTGQCLL 74

 Score = 37.0 bits (84), Expect = 0.010,   Method: Compositional matrix adjust.
 Identities = 28/127 (22%), Positives = 55/127 (43%), Gaps = 2/127 (1%)
 Frame = -2

Query: 110 NFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSC-CRFLDDNQIITSSGDTTCAL 168
           N +     D    ++ LK    N  +   L GH   + C C +    ++++ S D T  +
Sbjct: 385 NMIISAATDRTLRVWCLK----NTCLLHTLRGHNDDVECVCIY--GRRVVSGSWDKTLIV 224

Query: 169 WDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTF-IGHES 227
           W+++TG+      GH+  + ++    D    VSG+ D  ++ W +    C  T   G + 
Sbjct: 223 WEVDTGRPVHQLHGHTEAITAVQF--DEGKAVSGSADGDVRTWALDTGQCLLTMTTGQDI 50

Query: 228 DINAVAF 234
           ++  V +
Sbjct: 49  EVYCVVY 29

 Score = 29.6 bits (65), Expect = 1.9,   Method: Compositional matrix adjust.
 Identities = 19/83 (22%), Positives = 40/83 (48%), Gaps = 1/83 (1%)
 Frame = -2

Query: 199 FVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRAD 258
            +S A D ++++W ++++    T  GH  D+  V  +  G    +GS D T  ++++   
Sbjct: 379 IISAATDRTLRVWCLKNTCLLHTLRGHNDDVECVCIY--GRRVVSGSWDKTLIVWEVDTG 206

Query: 259 QEL-LMYSHDNIICGITSVAFSR 280
           + +  ++ H      IT+V F  
Sbjct: 205 RPVHQLHGHTE---AITAVQFDE 146

 Score = 28.5 bits (62), Expect = 4.2,   Method: Compositional matrix adjust.
 Identities = 15/57 (26%), Positives = 26/57 (45%)
 Frame = -2

Query: 284 LLLAGYDDFNCNIWDAMKGDRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
           ++++   D    +W          L GH++ V C+ +   G  V +GSWD  L +W 
Sbjct: 382 MIISAATDRTLRVWCLKNTCLLHTLRGHNDDVECVCIY--GRRVVSGSWDKTLIVWE 218
>21921
          Length = 1341

 Score = 40.0 bits (92), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 36/143 (25%), Positives = 63/143 (44%), Gaps = 2/143 (1%)
 Frame = -1

Query: 176 QTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTF-IGHESDINAVAF 234
           Q + + GH+G V S+   P G+  VSG+ D +I+ W+V    C +T  +G    + +VA+
Sbjct: 507 QALVYKGHTGIVRSICPDPTGQWLVSGSDDGTIRFWEVSSGRCMKTLQVG--GCVTSVAW 334

Query: 235 FPN-GYAFTTGSDDATCRLFDLRADQELLMYSHDNIICGITSVAFSRSGRLLLAGYDDFN 293
            PN        + + T  L +     +L++ + D ++      A S S +     +    
Sbjct: 333 NPNPSLCVVAATLNTTVLLINPGLGDKLVVSNTDKLLLASEDQASSSSEKEQPVDWVRTE 154

Query: 294 CNIWDAMKGDRAGVLAGHDNRVS 316
            N+ D   G R  +   H   VS
Sbjct: 153 LNVEDYTSGVRLRL--EHPKEVS 91
>10264
          Length = 416

 Score = 39.7 bits (91), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 32/132 (24%), Positives = 59/132 (44%), Gaps = 20/132 (15%)
 Frame = -1

Query: 102 TCAYAPSGNFVACGGLDNICSIYSLKT---------REGNVRVS------RELPGHTGYL 146
           + A +P  +++A  G D +  +  L +         REG+          REL GH+  +
Sbjct: 413 SPAGSPRCHWLAAAGNDQVIHVVDLASVFGEMGATEREGDKETLLILTSLRELSGHSQRV 234

Query: 147 SCCRF--LDDNQIITSSGDTTCALWDIETGQQTVGFAGHSGDVMSLS---LAPDGRTFVS 201
           +   +    D ++++   D    +WD++ G     F GH G +++     L PD    ++
Sbjct: 233 TDMSWSPHHDARLVSVGYDAEAFVWDVQKGTALAQFKGHMGRLLTCQFSGLDPD--LVMT 60

Query: 202 GACDASIKLWDV 213
           G  DAS+ +W V
Sbjct: 59  GGSDASVHVWRV 24

 Score = 28.1 bits (61), Expect = 5.5,   Method: Compositional matrix adjust.
 Identities = 19/58 (32%), Positives = 26/58 (44%), Gaps = 1/58 (1%)
 Frame = -1

Query: 283 RLLLAGYDDFNCNIWDAMKGDRAGVLAGHDNR-VSCLGVTDDGMAVATGSWDSFLKIW 339
           RL+  GYD     +WD  KG       GH  R ++C     D   V TG  D+ + +W
Sbjct: 200 RLVSVGYD-AEAFVWDVQKGTALAQFKGHMGRLLTCQFSGLDPDLVMTGGSDASVHVW 30
>33180
          Length = 460

 Score = 39.7 bits (91), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 30/105 (28%), Positives = 48/105 (45%), Gaps = 7/105 (6%)
 Frame = -2

Query: 183 HSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYA-F 241
           HS  + SL  + D    V GA D  + ++D   +        H+ D+NAVAF  +     
Sbjct: 456 HSFCIFSLMFSSDNTEIVGGANDGCLYVYDRESNQRTLKIDAHDDDVNAVAFADDSSQIL 277

Query: 242 TTGSDDATCRLFD---LRADQEL---LMYSHDNIICGITSVAFSR 280
            +G DD  C+++D   LR D  L   +M  H + +  I +   +R
Sbjct: 276 YSGGDDGLCKVWDRRTLREDNPLPVGIMAGHSDGVTYIDTKGDAR 142
>15118
          Length = 1074

 Score = 38.9 bits (89), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 20/77 (25%), Positives = 37/77 (48%)
 Frame = +3

Query: 137 RELPGHTGYLSCCRFLDDNQIITSSGDTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDG 196
           +EL    G        D N +     D T ++ D++T +    F+GHS  +  LS + DG
Sbjct: 312 KELKMSEGISRILLHRDSNMLAVVLEDFTVSVIDVDTLRVVRVFSGHSNSITDLSFSGDG 491

Query: 197 RTFVSGACDASIKLWDV 213
           R  ++ + D +++ W +
Sbjct: 492 RWLITASMDCTVRTWSL 542

 Score = 37.4 bits (85), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 30/149 (20%), Positives = 60/149 (40%), Gaps = 4/149 (2%)
 Frame = +3

Query: 196 GRTFVSGACDASIKLWDVRDSMCRQTF---IGHESDINAVAFFPNGYAFTTGSDDATCRL 252
           G     G     + +++++    R +F   + H S +  VAF        T   D   + 
Sbjct: 93  GNYVAVGYSSGHLDIYNLQSGKHRGSFGDTVAHVSGVRGVAFDAFNCLLITAGGDCDIKF 272

Query: 253 FDLRA-DQELLMYSHDNIICGITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDRAGVLAGH 311
           +   + D+  ++     +  GI+ +   R   +L    +DF  ++ D        V +GH
Sbjct: 273 WRFGSRDRARVLLKELKMSEGISRILLHRDSNMLAVVLEDFTVSVIDVDTLRVVRVFSGH 452

Query: 312 DNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
            N ++ L  + DG  + T S D  ++ W+
Sbjct: 453 SNSITDLSFSGDGRWLITASMDCTVRTWS 539
>19140
          Length = 573

 Score = 38.1 bits (87), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 22/71 (30%), Positives = 36/71 (50%)
 Frame = -3

Query: 173 TGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAV 232
           T  + +   GH+ +V +L L  DG   +SG+ D +I+LW +    C  TF  H+  + A+
Sbjct: 520 TCHKLMKLKGHTDNVKALVLNRDGTQCLSGSSDGTIRLWSLGQQRCVATFRVHDEGVWAL 341

Query: 233 AFFPNGYAFTT 243
                  +FTT
Sbjct: 340 QA---NESFTT 317
>34005
          Length = 456

 Score = 37.4 bits (85), Expect = 0.010,   Method: Compositional matrix adjust.
 Identities = 28/110 (25%), Positives = 49/110 (44%), Gaps = 6/110 (5%)
 Frame = +1

Query: 186 DVMSLSLAPDGRTFVSGACDASIKLWDVR---DSMCRQTFIGHESDINAVAFFP---NGY 239
           +V  LS +PD     SG+ D S+ +WD     D     T   H++ + AVA+ P      
Sbjct: 118 EVCGLSWSPDATFLASGSNDNSVNIWDSTLGMDVPPLHTLTSHQAAVKAVAWCPWQTRML 297

Query: 240 AFTTGSDDATCRLFDLRADQELLMYSHDNIICGITSVAFSRSGRLLLAGY 289
           A   G++D   R ++      +      + +C   SV + +  R L++G+
Sbjct: 298 ATGGGTNDRHIRFWNTNTGACVKAVDTQSQVC---SVLWCKEHRELVSGH 438
>27806
          Length = 419

 Score = 37.0 bits (84), Expect = 0.013,   Method: Compositional matrix adjust.
 Identities = 20/78 (25%), Positives = 37/78 (47%), Gaps = 1/78 (1%)
 Frame = -1

Query: 187 VMSLSLAPDGRTFV-SGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTTGS 245
           V  +S++  G   + + + D + +++ +    C  T+ GH+  +NAV F P      T S
Sbjct: 419 VWEVSVSRPGHPIIGTASADHTARIYSIETGACVLTYGGHQGSVNAVRFHPGQDLVLTAS 240

Query: 246 DDATCRLFDLRADQELLM 263
            D T  ++  +  Q  LM
Sbjct: 239 GDHTAHVWRAQFSQPSLM 186

 Score = 32.0 bits (71), Expect = 0.41,   Method: Compositional matrix adjust.
 Identities = 16/55 (29%), Positives = 28/55 (50%)
 Frame = -1

Query: 157 IITSSGDTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLW 211
           I T+S D T  ++ IETG   + + GH G V ++   P     ++ + D +  +W
Sbjct: 380 IGTASADHTARIYSIETGACVLTYGGHQGSVNAVRFHPGQDLVLTASGDHTAHVW 216
>35607
          Length = 475

 Score = 35.4 bits (80), Expect = 0.031,   Method: Compositional matrix adjust.
 Identities = 31/141 (21%), Positives = 56/141 (39%)
 Frame = +2

Query: 193 APDGRTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRL 252
            PDG    +G  D +++ WD+R+    Q      S I ++ + P G     G + +   +
Sbjct: 5   PPDGTKLWTGGLDNTVRSWDLREGRQLQQH-DFSSQIFSLGYCPTGDWLAVGMESSNVEV 181

Query: 253 FDLRADQELLMYSHDNIICGITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDRAGVLAGHD 312
                  +  ++ H++ +    S+ F+  G+  ++   D   N W    G          
Sbjct: 182 LHHSKPDKYQLHLHESCVL---SLKFAYCGKWFVSTGKDNLLNAWRTPYGASIFQSKESS 352

Query: 313 NRVSCLGVTDDGMAVATGSWD 333
           + +SC    DD   V TGS D
Sbjct: 353 SVLSCDIAADDKYIV-TGSGD 412

 Score = 32.3 bits (72), Expect = 0.31,   Method: Compositional matrix adjust.
 Identities = 35/142 (24%), Positives = 65/142 (45%), Gaps = 4/142 (2%)
 Frame = +2

Query: 34  TAGLDPVGR-IQMRTRRTLRGH--LAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKV 90
           T GLD   R   +R  R L+ H   ++I+++ +      L    +   + +      +K 
Sbjct: 29  TGGLDNTVRSWDLREGRQLQQHDFSSQIFSLGYCPTGDWLAVGMESSNVEVLHHSKPDK- 205

Query: 91  HAIPLRSSWVMTCAYAPSGNFVACGGLDNICSIYSLKTREG-NVRVSRELPGHTGYLSCC 149
           + + L  S V++  +A  G +    G DN+ + +  +T  G ++  S+E    +  LSC 
Sbjct: 206 YQLHLHESCVLSLKFAYCGKWFVSTGKDNLLNAW--RTPYGASIFQSKE---SSSVLSCD 370

Query: 150 RFLDDNQIITSSGDTTCALWDI 171
              DD  I+T SGD    L+++
Sbjct: 371 IAADDKYIVTGSGDKKATLYEV 436
>18320
          Length = 450

 Score = 35.0 bits (79), Expect = 0.047,   Method: Compositional matrix adjust.
 Identities = 22/83 (26%), Positives = 37/83 (44%), Gaps = 9/83 (10%)
 Frame = -2

Query: 267 DNIICGITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDRAGVLAGHDNRVSCLGVTDDG-- 324
           D +   +  V   ++G+LL AG  D    + D  K D A   +  D ++ C+     G  
Sbjct: 293 DILFAAVDVVHLMQNGQLLAAGSRDRYLTLLDLTKYDPARPKSKKDMQLHCIDKAHSGWI 114

Query: 325 -------MAVATGSWDSFLKIWN 340
                    + TGSWD+ +K+W+
Sbjct: 113 WCMASLNQHLYTGSWDTKIKVWD 45
>17298
          Length = 476

 Score = 34.7 bits (78), Expect = 0.057,   Method: Compositional matrix adjust.
 Identities = 18/84 (21%), Positives = 36/84 (42%)
 Frame = -1

Query: 170 DIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHESDI 229
           ++ +GQ    +  H+G V  +    +    +SG+ D +++ WD R        +  E+  
Sbjct: 254 NVASGQALRKYRDHAGTVNCVKFNEESTVILSGSLDNTVRAWDTRSRSHTPIQVLDEATD 75

Query: 230 NAVAFFPNGYAFTTGSDDATCRLF 253
           +  +   + Y   TGS D   R +
Sbjct: 74  SVTSIQVSDYEILTGSADGRVRRY 3
>22114
          Length = 1140

 Score = 34.3 bits (77), Expect = 0.071,   Method: Compositional matrix adjust.
 Identities = 47/227 (20%), Positives = 83/227 (36%), Gaps = 27/227 (11%)
 Frame = -3

Query: 141 GHTGYLSCCRFLDDNQIITSSGDTTCALWDIETGQQTVGFAGHSGDVM--------SLSL 192
            HT +++      D +   S+ D    LW++E   Q+          M        +   
Sbjct: 826 AHTYHINSISVNSDQETYLSADDLRVNLWNLEVTNQSFNIVDIKPANMEELTEVITAAEF 647

Query: 193 APDG-RTFVSGACDASIKLWDVRD-SMCRQTFIGHESDINAVAFFPNGYAFTTGSDDATC 250
            P+   +FV  +   SI+L D+R+ ++C         D +A  F           +D T 
Sbjct: 646 HPNMCSSFVYSSSKGSIRLCDMRNQALC---------DKHAKLF--------EEPEDPTN 518

Query: 251 RLFDLRADQELLMYSHDNIICGITSVAFSRSGRLLLAGYDDFNCNIWD-AMKGDRAGVLA 309
           R F               II  I+ V FS  GR ++   D  +  +WD AM+        
Sbjct: 517 RSF------------FSEIISSISDVKFSHDGRYMMTR-DYLSVKLWDLAMESRPVETFQ 377

Query: 310 GHD----------------NRVSCLGVTDDGMAVATGSWDSFLKIWN 340
            H+                ++  C    DD   + TGS+++F ++++
Sbjct: 376 VHEYLRSKLCSLYENDCIFDKFECSWSADD-RHIMTGSYNNFFRMFD 239
>31474
          Length = 403

 Score = 33.9 bits (76), Expect = 0.090,   Method: Compositional matrix adjust.
 Identities = 18/55 (32%), Positives = 29/55 (52%), Gaps = 2/55 (3%)
 Frame = -3

Query: 182 GHSGDVMSLSLAPDGRTFVSGACDASIKLWDVR--DSMCRQTFIGHESDINAVAF 234
            H+  V SL  +P G    S + DA+  +W  +  +  C  T  GHE+++ AVA+
Sbjct: 176 AHTRTVRSLGWSPCGNYLSSASFDATTAVWSRKGGEFECIATLEGHENEVKAVAW 12
>11915
          Length = 737

 Score = 33.1 bits (74), Expect = 0.15,   Method: Compositional matrix adjust.
 Identities = 18/66 (27%), Positives = 32/66 (48%), Gaps = 3/66 (4%)
 Frame = +1

Query: 153 DDNQIITSSGDTT--CALWDIETGQQTVGFAGHSGDVMSLSLAPDGRT-FVSGACDASIK 209
           D + ++ ++G  +    LW+ ETG+  +    H   V  L  A D     +S + D ++K
Sbjct: 433 DSSTLVLATGHVSGRIKLWNCETGKLLIEMMDHKATVHDLHFAADNSLCLMSASHDGTVK 612

Query: 210 LWDVRD 215
           LW+  D
Sbjct: 613 LWEFDD 630

 Score = 28.5 bits (62), Expect = 4.0,   Method: Compositional matrix adjust.
 Identities = 28/108 (25%), Positives = 48/108 (44%), Gaps = 10/108 (9%)
 Frame = +1

Query: 19  RDARKACGDSTLTQITAGLDPVGRIQMRTRRT------LRGHLAKIYAMHWGTDSRL-LV 71
           R  R+   DS+ T + A     GRI++    T      +  H A ++ +H+  D+ L L+
Sbjct: 409 RWKRQQQNDSS-TLVLATGHVSGRIKLWNCETGKLLIEMMDHKATVHDLHFAADNSLCLM 585

Query: 72  SASQDGKLIIW---DSYTTNKVHAIPLRSSWVMTCAYAPSGNFVACGG 116
           SAS DG + +W   D    N    +   +    +C ++    +VA  G
Sbjct: 586 SASHDGTVKLWEFDDQGDCNMYLTLRTNAKHAFSCRWSHDRRYVATAG 729
>27270
          Length = 1078

 Score = 32.7 bits (73), Expect = 0.20,   Method: Compositional matrix adjust.
 Identities = 43/174 (24%), Positives = 60/174 (34%), Gaps = 14/174 (8%)
 Frame = +2

Query: 52  RGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNF 111
           +GH   +  M W  D R L S+S DG +I W+    N +H I     W  T     SG  
Sbjct: 263 KGHSKAVTDMCWRADGRTLYSSSLDGHVIGWN---VNTLHMI---EKWKAT-----SGRH 409

Query: 112 VACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQIITSSGDTTCALWDI 171
               G+  +C                         S  R L        + D T  +WD+
Sbjct: 410 ---HGVHCVC-----------------------LCSSSRLL--------TADHTIKMWDL 487

Query: 172 ETGQQTVGFAGHSGDVMSL--SLAPDGR------------TFVSGACDASIKLW 211
            T      F+GHS +V+ L   L P                F + A D +I +W
Sbjct: 488 TTKNVLQEFSGHSTEVIKLLPVLKPSSEQNDIGDSNLACYVFSAAAADRTINVW 649

 Score = 31.2 bits (69), Expect = 0.58,   Method: Compositional matrix adjust.
 Identities = 36/157 (22%), Positives = 60/157 (38%), Gaps = 5/157 (3%)
 Frame = +2

Query: 153 DDNQIITSSGDTTCALWDIETGQQTVGF-AGHSGDVMSLSLAPDGRTFVSGACDASIKLW 211
           D   +   S D +  L+ +ET   T     GHS  V  +    DGRT  S + D  +  W
Sbjct: 176 DSAVVAVGSADGSVGLYSVETHTYTHMLNKGHSKAVTDMCWRADGRTLYSSSLDGHVIGW 355

Query: 212 DVRDSMCRQTFI---GHESDINAVAFFPNGYAFTTGSDDATCRLFDLRADQELLMYS-HD 267
           +V      + +    G    ++ V    +    T    D T +++DL     L  +S H 
Sbjct: 356 NVNTLHMIEKWKATSGRHHGVHCVCLCSSSRLLTA---DHTIKMWDLTTKNVLQEFSGHS 526

Query: 268 NIICGITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDR 304
             +  +  V    S +  + G  +  C ++ A   DR
Sbjct: 527 TEVIKLLPVLKPSSEQNDI-GDSNLACYVFSAAAADR 634
>03734
          Length = 1963

 Score = 32.3 bits (72), Expect = 0.26,   Method: Compositional matrix adjust.
 Identities = 28/125 (22%), Positives = 51/125 (40%), Gaps = 11/125 (8%)
 Frame = -2

Query: 190  LSLAPDGRTFVSGACDASIKLWDVRDS--MCRQTFIGHESDINAVAFFPNGYAFTTGSDD 247
            L++ PD R  VS    +S+++WD+ D       T    E++      F N          
Sbjct: 1143 LAITPDNRYLVSATSVSSLQIWDISDDKGTLLHTVRPEETEEEGRHSFTNLCVSDNSKMA 964

Query: 248  ATCRLFDLRADQELLMYS--HDNIICGI-------TSVAFSRSGRLLLAGYDDFNCNIWD 298
            AT       +  ++ +YS     ++C +       T+++F+ + R LL  Y D     +D
Sbjct: 963  ATS-----NSGGQVHLYSIAEGEVLCKLPALSQQATAISFTXAARTLLVTYSDHKVMEFD 799

Query: 299  AMKGD 303
              K +
Sbjct: 798  VQKEE 784
>26939
          Length = 388

 Score = 32.3 bits (72), Expect = 0.27,   Method: Compositional matrix adjust.
 Identities = 13/58 (22%), Positives = 27/58 (46%)
 Frame = +2

Query: 157 IITSSGDTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVR 214
           ++++S D T  +WD+   +       H     S+         +SG+ D ++K+W+ R
Sbjct: 11  LVSASDDKTIRVWDLRNKRCMKTLYAHQHFCTSIDFHKAHPYVISGSVDQTVKVWECR 184

 Score = 32.0 bits (71), Expect = 0.41,   Method: Compositional matrix adjust.
 Identities = 17/62 (27%), Positives = 33/62 (53%), Gaps = 1/62 (1%)
 Frame = +2

Query: 238 GYAFTTGSDDATCRLFDLRADQEL-LMYSHDNIICGITSVAFSRSGRLLLAGYDDFNCNI 296
           G    + SDD T R++DLR  + +  +Y+H +     TS+ F ++   +++G  D    +
Sbjct: 2   GKYLVSASDDKTIRVWDLRNKRCMKTLYAHQHF---CTSIDFHKAHPYVISGSVDQTVKV 172

Query: 297 WD 298
           W+
Sbjct: 173 WE 178
>15745
          Length = 1183

 Score = 32.3 bits (72), Expect = 0.30,   Method: Compositional matrix adjust.
 Identities = 19/61 (31%), Positives = 29/61 (47%), Gaps = 3/61 (4%)
 Frame = +2

Query: 158 ITSSGDTTCALWDIETGQQTVGFAGHSGD-VMSLSLAPDGRTFVSGAC--DASIKLWDVR 214
           I ++ + T   WD+ + QQT    G  G  V  L   P+ R +   +C  D  +K WD R
Sbjct: 629 IATANEATIRGWDLRSKQQTYQMEGAHGQLVRDLDFNPN-RQYYLASCGDDCRVKFWDTR 805

Query: 215 D 215
           +
Sbjct: 806 N 808
>31864
          Length = 545

 Score = 32.3 bits (72), Expect = 0.32,   Method: Compositional matrix adjust.
 Identities = 32/157 (20%), Positives = 58/157 (36%)
 Frame = +2

Query: 54  HLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFVA 113
           H   I  M    D  + V+AS+D    ++DS +   +         V + A +P  + V 
Sbjct: 47  HTGGINDMQLSKDGTMFVTASKDTTAKLFDSESLMCLKTYKTERP-VNSAAISPILDHVV 223

Query: 114 CGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQIITSSGDTTCALWDIET 173
            GG  +   + +  T+ G                  RF                +++ E 
Sbjct: 224 LGGGQDAMEVTTTSTKAGKFD--------------SRFFH-------------LIYEEEF 322

Query: 174 GQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKL 210
            +      GH G + SL+  PDG+++ SG  D  +++
Sbjct: 323 AR----LKGHFGPINSLAFHPDGKSYASGGEDGFVRV 421
>15972
          Length = 1069

 Score = 32.0 bits (71), Expect = 0.37,   Method: Compositional matrix adjust.
 Identities = 11/33 (33%), Positives = 22/33 (66%)
 Frame = +3

Query: 180 FAGHSGDVMSLSLAPDGRTFVSGACDASIKLWD 212
           F+GH G V  L++ P G+  ++ + D +++LW+
Sbjct: 225 FSGHKGPVRHLAVHPSGKLTLTVSQDRTLRLWN 323

 Score = 28.9 bits (63), Expect = 3.2,   Method: Compositional matrix adjust.
 Identities = 13/35 (37%), Positives = 20/35 (57%)
 Frame = +3

Query: 220 QTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFD 254
           +TF GH+  +  +A  P+G    T S D T RL++
Sbjct: 219 RTFSGHKGPVRHLAVHPSGKLTLTVSQDRTLRLWN 323
>15337
          Length = 860

 Score = 32.0 bits (71), Expect = 0.39,   Method: Compositional matrix adjust.
 Identities = 17/54 (31%), Positives = 30/54 (55%), Gaps = 2/54 (3%)
 Frame = -1

Query: 183 HSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDS--MCRQTFIGHESDINAVAF 234
           + G ++ +  +PDG+  V+G  D  + +W   +   +CR    GH+S +N VAF
Sbjct: 206 YFGGLLCVCWSPDGKYIVTGGEDDLVTVWSFHEKRVVCRGH--GHKSWVNVVAF 51

 Score = 30.4 bits (67), Expect = 0.98,   Method: Compositional matrix adjust.
 Identities = 18/85 (21%), Positives = 39/85 (45%)
 Frame = -1

Query: 67  SRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFVACGGLDNICSIYSL 126
           SR L    QDG L +++  +   +  +      ++   ++P G ++  GG D++ +++S 
Sbjct: 293 SRYLAVVGQDGHLRVFNYNSMELIGTMKSYFGGLLCVCWSPDGKYIVTGGEDDLVTVWSF 114

Query: 127 KTREGNVRVSRELPGHTGYLSCCRF 151
             +    RV     GH  +++   F
Sbjct: 113 HEK----RVVCRGHGHKSWVNVVAF 51
>04358
          Length = 2430

 Score = 31.6 bits (70), Expect = 0.47,   Method: Compositional matrix adjust.
 Identities = 37/179 (20%), Positives = 71/179 (39%), Gaps = 21/179 (11%)
 Frame = +1

Query: 183  HSGDVMSLSLAPDG-RTFVSGACDASIKLWDVRDS---------------MCRQTFIGHE 226
            H  D+  +   P   +T ++G+ D  + ++DV  +               + R  + G +
Sbjct: 1702 HHDDITQVHFGPTSEKTLLTGSTDGLVNVFDVMQTTEDDALMSTYNTEATVERAGWCGPQ 1881

Query: 227  SD-INAVAFFPNGYAFTTGSDDATCRLFDLRADQELLMYSHDNIICGITSVAFSRSGRLL 285
            S  + A+    + + + T  D+   +L DL  +Q+L      + +        S S   L
Sbjct: 1882 SQQVYAITHMLSWHVWDTEKDEDVQQLTDL--EQKLQGQCQADYLVDCIPANQSTSPPCL 2055

Query: 286  LAGYDDFNCNIWDAMKGDRAGVL----AGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
            +AG    + ++ D    +   V+     GH + V CL        + TG  DS L +W+
Sbjct: 2056 VAGTHTGDLHVLDLSDLEEVKVVRSLSGGHTDTVRCLHWDKQTQTLVTGGEDSMLCLWS 2232

 Score = 28.1 bits (61), Expect = 4.8,   Method: Compositional matrix adjust.
 Identities = 12/42 (28%), Positives = 23/42 (54%), Gaps = 1/42 (2%)
 Frame = +1

Query: 44   QMRTRRTLRG-HLAKIYAMHWGTDSRLLVSASQDGKLIIWDS 84
            +++  R+L G H   +  +HW   ++ LV+  +D  L +W S
Sbjct: 2110 EVKVVRSLSGGHTDTVRCLHWDKQTQTLVTGGEDSMLCLWSS 2235
>07665
          Length = 435

 Score = 31.6 bits (70), Expect = 0.48,   Method: Compositional matrix adjust.
 Identities = 27/97 (27%), Positives = 39/97 (40%), Gaps = 8/97 (8%)
 Frame = -2

Query: 211 WDVRDSMCRQTFIGHESDINAVAFFPNGYAFTTGSD------DATCR--LFDLRADQELL 262
           WD+ D     T + H   INA+ F PN Y             D  C+  + +LR +    
Sbjct: 392 WDLNDGKNLYT-LEHNDIINALCFSPNRYWLCVAYGPSIKIWDLACKKTVEELRPEVVSP 216

Query: 263 MYSHDNIICGITSVAFSRSGRLLLAGYDDFNCNIWDA 299
               +   C   S+A+S  G+ L AGY D    +W  
Sbjct: 215 TSKAEQPQC--LSLAWSTDGQTLFAGYSDNTIRVWQV 111
>04088
          Length = 511

 Score = 31.2 bits (69), Expect = 0.58,   Method: Compositional matrix adjust.
 Identities = 18/58 (31%), Positives = 26/58 (44%), Gaps = 2/58 (3%)
 Frame = +3

Query: 158 ITSSGDTTCALWDIETGQQTVGFAGHSGDVMSLS--LAPDGRTFVSGACDASIKLWDV 213
           + SS D T  L D +TG+    F GH      +   L  +    VSG+ D  +  WD+
Sbjct: 78  LVSSQDNTVRLMDKDTGEMLNEFTGHKHSQYKIDSCLNNEDTLVVSGSEDGKVYFWDL 251

 Score = 30.0 bits (66), Expect = 1.4,   Method: Compositional matrix adjust.
 Identities = 21/73 (28%), Positives = 30/73 (41%), Gaps = 4/73 (5%)
 Frame = +3

Query: 272 GITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDRAGVLAGHDNRV----SCLGVTDDGMAV 327
            +TSV F+R G+  L    D    + D   G+      GH +      SCL   D    V
Sbjct: 36  AVTSVTFTRDGQCSLVSSQDNTVRLMDKDTGEMLNEFTGHKHSQYKIDSCLNNED--TLV 209

Query: 328 ATGSWDSFLKIWN 340
            +GS D  +  W+
Sbjct: 210 VSGSEDGKVYFWD 248
>31054
          Length = 392

 Score = 30.8 bits (68), Expect = 0.84,   Method: Compositional matrix adjust.
 Identities = 19/58 (32%), Positives = 28/58 (48%)
 Frame = -2

Query: 199 FVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFDLR 256
           F  G+ D  +K W   D    Q   GH + IN +A   +G    +G+D+ T  L+D R
Sbjct: 367 FAXGSPDX-VKQWKFPDGNFIQNLSGHNAIINTLAVNSDG-VLVSGADNGTMHLWDWR 200
>12140
          Length = 727

 Score = 30.8 bits (68), Expect = 0.90,   Method: Compositional matrix adjust.
 Identities = 39/141 (27%), Positives = 54/141 (38%), Gaps = 4/141 (2%)
 Frame = +2

Query: 100 VMTCAYAPS--GNFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQI 157
           V +  +AP   G  +ACG  D   SI S  T +GN    +    HT  + C      N +
Sbjct: 47  VNSVCFAPHELGLILACGSSDGSLSIIST-TGDGNWDSKKINNAHT--IGC------NAV 199

Query: 158 ITSSGDTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLW--DVRD 215
             +      AL+D    QQ V                  + FVSG CD  +K+W  D   
Sbjct: 200 SWAPSTAPNALFDQSARQQPV------------------KRFVSGGCDNLVKIWREDETG 325

Query: 216 SMCRQTFIGHESDINAVAFFP 236
            +  Q   GH   +  VA+ P
Sbjct: 326 WVEDQKLEGHSDWVRDVAWAP 388

 Score = 28.5 bits (62), Expect = 4.6,   Method: Compositional matrix adjust.
 Identities = 24/89 (26%), Positives = 40/89 (44%), Gaps = 13/89 (14%)
 Frame = +2

Query: 49  RTLRGHLAKIYAMHW----GTDSRLLVSASQDGKLIIW------DSYTT---NKVHAIPL 95
           + L GH   +  + W    G    ++ S SQD ++IIW      + +T+   NK   +  
Sbjct: 338 QKLEGHSDWVRDVAWAPSIGLPRNVIASCSQDCRVIIWTNDGSSNQWTSRILNKFSDVVW 517

Query: 96  RSSWVMTCAYAPSGNFVACGGLDNICSIY 124
             SW +T      GN +A  G DN  +++
Sbjct: 518 HVSWSVT------GNILAVSGGDNKVTLW 586
>20662
          Length = 1220

 Score = 30.4 bits (67), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 24/73 (32%), Positives = 36/73 (49%), Gaps = 4/73 (5%)
 Frame = +2

Query: 65  TDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSS-WVMTCA-YAPSG-NFVACGGLDNIC 121
           T+  L +S SQDGK+++WD   +     +P  SS +  TC  + P+  N  A G      
Sbjct: 542 TEPALFLSCSQDGKIVLWDVRESKPATCLPKCSSGFKPTCVQWQPNARNMYAVGDEGGHV 721

Query: 122 SIYSLK-TREGNV 133
           S+  L+   E NV
Sbjct: 722 SVQDLRMVVEKNV 760

 Score = 29.3 bits (64), Expect = 2.4,   Method: Compositional matrix adjust.
 Identities = 33/141 (23%), Positives = 58/141 (41%), Gaps = 6/141 (4%)
 Frame = +2

Query: 153 DDNQIITSSGDTTCALWDIETGQQTVGFAGHSGDVMSLSLAP-DGRTFVSGACDASIKLW 211
           D +  +++S D    +W+ +       +  HS  V  +   P +   F+S + D  I LW
Sbjct: 419 DXSHYLSASYDHGIKVWNTDL-TSLYTYRAHSDIVWDVQCHPTEPALFLSCSQDGKIVLW 595

Query: 212 DVRDSMCRQTFIGHESDINA--VAFFPNGY-AFTTGSDDATCRLFDLR--ADQELLMYSH 266
           DVR+S          S      V + PN    +  G +     + DLR   ++ +   SH
Sbjct: 596 DVRESKPATCLPKCSSGFKPTCVQWQPNARNMYAVGDEGGHVSVQDLRMVVEKNVSYQSH 775

Query: 267 DNIICGITSVAFSRSGRLLLA 287
           + +   +T +AF      +LA
Sbjct: 776 NRV---VTRLAFCPQRPSMLA 829
>17807
          Length = 484

 Score = 29.6 bits (65), Expect = 1.8,   Method: Compositional matrix adjust.
 Identities = 30/142 (21%), Positives = 61/142 (42%), Gaps = 10/142 (7%)
 Frame = -2

Query: 66  DSRLLVSASQDGKLIIWDSYTTNKV---HAIPLRSSWVMTCAYAPSGNFVACGGLDNICS 122
           D R  +S S DGK+ +W+     KV   + +   S+ + T ++  +G     G  D  C 
Sbjct: 426 DDRYFLSGSLDGKIRLWN-IPDKKVTMWNELSGSSNLITTASFCHNGRLAVVGTYDGRCI 250

Query: 123 IYSLKTREG----NVRVSRELPGHTGYLSCCRFLD-DNQIITSSGDTTCALWDIETGQQT 177
            Y+    +     NVR +R        ++    +  + +I+ +S D+   L+ ++    T
Sbjct: 249 FYTTDQLKYYTMLNVRSTRGRNARGRKITGIEAMPGEEKILVTSNDSRVRLYSLKDLTLT 70

Query: 178 VGFAG--HSGDVMSLSLAPDGR 197
             + G  ++   +  S +P G+
Sbjct: 69  CKYKGCTNNSSQIKASFSPTGK 4
>04524
          Length = 1340

 Score = 29.6 bits (65), Expect = 2.0,   Method: Compositional matrix adjust.
 Identities = 17/58 (29%), Positives = 32/58 (55%), Gaps = 11/58 (18%)
 Frame = -1

Query: 129 REGNVRVSRELP----------GHTGYLSCCRFLDDNQIITS-SGDTTCALWDIETGQ 175
           R+  +RVS + P          GHT +++C  ++++ +++ S SGD T   W++E  Q
Sbjct: 968 RDEKIRVS-QFPNAYNIHTYCLGHTQFVNCLVYVEEFRVLISGSGDCTVRAWNMEGKQ 798
>22113
          Length = 614

 Score = 28.9 bits (63), Expect = 3.3,   Method: Compositional matrix adjust.
 Identities = 22/82 (26%), Positives = 41/82 (50%), Gaps = 1/82 (1%)
 Frame = +3

Query: 91  HAIPLRSSWVMTCAYAPSGNFVACGGLDNICSIYSLKTREG-NVRVSRELPGHTGYLSCC 149
           + + L  S V++  +A  G +    G DN+ + +  +T  G ++  S+E    +  LSC 
Sbjct: 84  YQLHLHESCVLSLRFATCGKWFVSTGKDNLLNAW--RTPYGASIFQSKET---SSVLSCD 248

Query: 150 RFLDDNQIITSSGDTTCALWDI 171
              DD  I+T SGD    ++++
Sbjct: 249 ISTDDKYIVTGSGDKKATVYEV 314
>15780
          Length = 735

 Score = 28.1 bits (61), Expect = 5.0,   Method: Compositional matrix adjust.
 Identities = 15/59 (25%), Positives = 28/59 (47%)
 Frame = -1

Query: 68  RLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFVACGGLDNICSIYSL 126
           + L +A  D  +I+WD  +   V  +   +  V    ++  G  +A GG+DN   ++ L
Sbjct: 735 KYLSTAGADHTVIVWDIASGTAVAHLTAHTDTVYALCFSRDGTVLASGGMDNSIRLWDL 559
>16105
          Length = 960

 Score = 27.7 bits (60), Expect = 7.0,   Method: Compositional matrix adjust.
 Identities = 36/130 (27%), Positives = 51/130 (39%), Gaps = 12/130 (9%)
 Frame = -2

Query: 96  RSSWVMT-CAYAPSGNFVACGGLDNICSIYSLKTREGNVRVSREL-PGHTGYLSCCRFL- 152
           R+SW  T CA  P    V          +    +R G V V   L  GH G +   ++  
Sbjct: 722 RTSWESTYCAVNPKFVAVMTEAAGGGAFLVLPLSRVGRVPVDNPLVAGHKGAVLDIQWCP 543

Query: 153 -DDNQIITSSGDTTCALWDI-ETGQQT------VGFAGHSGDVMSLSLAPDGR-TFVSGA 203
            +DN I ++S D T  +W I ++G  T      V   GH      +   P  +   VS  
Sbjct: 542 HNDNVIASASDDCTVKVWQIPDSGLVTNLTDPVVDLVGHQKRCCLIVWHPSAQNVLVSAG 363

Query: 204 CDASIKLWDV 213
            D  I  W+V
Sbjct: 362 ADNKILFWNV 333
>38177
          Length = 430

 Score = 27.7 bits (60), Expect = 7.1,   Method: Compositional matrix adjust.
 Identities = 14/50 (28%), Positives = 22/50 (44%), Gaps = 4/50 (8%)
 Frame = +3

Query: 51  LRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTN----KVHAIPLR 96
           L+ H   + AM W    + +V+A   G +  W S   N    + H  P+R
Sbjct: 102 LQAHDVSVRAMRWSNHDQWMVTADHSGYIKYWQSNMNNVKMFQGHKEPIR 251

 Score = 27.7 bits (60), Expect = 7.5,   Method: Compositional matrix adjust.
 Identities = 13/65 (20%), Positives = 28/65 (43%)
 Frame = +3

Query: 276 VAFSRSGRLLLAGYDDFNCNIWDAMKGDRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSF 335
           +A++  GR L+ G       +W+ +  +   +L  HD  V  +  ++    + T     +
Sbjct: 6   LAWTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDVSVRAMRWSNHDQWMVTADHSGY 185

Query: 336 LKIWN 340
           +K W 
Sbjct: 186 IKYWQ 200
>00825
          Length = 1821

 Score = 27.3 bits (59), Expect = 8.6,   Method: Compositional matrix adjust.
 Identities = 14/52 (26%), Positives = 22/52 (42%)
 Frame = -2

Query: 162  GDTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDV 213
            G+  C  W++   Q       H G V  ++    G+ F S   D +IK W +
Sbjct: 1805 GELIC--WNLPKQQMACRVQAHDGIVHGMAAHSSGQYFFSCGSDKTIKQWSL 1656
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31982847|ref|NP_032103.2| glutamic acid decarboxylase
1 [Mus musculus]
         (593 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

18263                                                                 263   1e-77
17810                                                                 185   1e-55
22458                                                                  71   5e-21
11435                                                                  89   4e-18
20610                                                                  32   0.64 
30109                                                                  32   0.94 
13106                                                                  31   1.2  
23871                                                                  30   4.0  
>18263
          Length = 788

 Score =  263 bits (672), Expect(2) = 1e-77,   Method: Compositional matrix adjust.
 Identities = 123/217 (56%), Positives = 154/217 (70%)
 Frame = +1

Query: 376 GGGLLMSRKHRHKLSGIERANSVTWNPHKMMGVLLQCSAILVKEKGILQGCNQMCAGYLF 435
           GG +L+S   RHK++GIE  +S+TWNPHKMMG  LQ SA   K K +L+ C+   A YLF
Sbjct: 100 GGAVLLSDSLRHKMTGIELCDSLTWNPHKMMGAPLQSSAFFTKHKTLLEHCHSAKAKYLF 279

Query: 436 QPDKQYDVSYDTGDKAIQCGRHVDIFKFWLMWKAKGTVGFENQINKCLELADYLYAKIKN 495
           Q DK YDVSYDTGDK+IQCGR VD+ K W+MWK+KG+V F   I      A YL  K+K 
Sbjct: 280 QQDKFYDVSYDTGDKSIQCGRKVDVLKLWMMWKSKGSVQFAKDIENIFNCAQYLTTKLKA 459

Query: 496 REEFEMVFDGEPEHTNVCFWYIPQSLRGVPDSPERREKLHRVAPKIKALMMESGTTMVGY 555
            E F +V D EPE TNVCFWYIP SLRG P++ +   ++ +VAP+IK  M+E GT +VGY
Sbjct: 460 MEGFRLVVD-EPECTNVCFWYIPPSLRGQPETQDWWSQVAKVAPQIKQRMVEQGTLLVGY 636

Query: 556 QPQGDKANFFRMVISNPAATQSDIDFLIEEIERLGQD 592
           QP GD+ NFFRM++SN AAT +D+DF+  EI RLG D
Sbjct: 637 QPDGDRVNFFRMIVSNTAATFADMDFVASEIARLGHD 747

 Score = 45.4 bits (106), Expect(2) = 1e-77,   Method: Compositional matrix adjust.
 Identities = 18/33 (54%), Positives = 27/33 (81%), Gaps = 1/33 (3%)
 Frame = +2

Query: 344 AGTTVYGAFDPIQEIADICEKY-NLWLHVDAAW 375
           AG+TV G++DP+ +IA +C K+ ++WLHVD AW
Sbjct: 2   AGSTVLGSYDPLDKIAAVCRKHGDIWLHVDGAW 100
>17810
          Length = 667

 Score =  185 bits (469), Expect(2) = 1e-55,   Method: Compositional matrix adjust.
 Identities = 89/188 (47%), Positives = 125/188 (66%), Gaps = 2/188 (1%)
 Frame = +1

Query: 404 KMMGVLLQCSAILVKEKGILQGCNQMCAGYLFQPDKQYDVSYDTGDKAIQCGRHVDIFKF 463
           KM  V +Q SA++VKEKG+LQ  N + A YLFQPDK YD SYD GD+++QCGR VD+ K 
Sbjct: 106 KMCHVTIQASALMVKEKGMLQKANGLNAEYLFQPDKPYDTSYDIGDRSVQCGRKVDVVKV 285

Query: 464 WLMWKAKGTVGFENQINKCLELADYLYAKIKNREEFEMVFDGEPEHTNVCFWYIPQSLRG 523
           W+ WK  G  G  + + +  E ++YL  K++ RE F +V   + E TN+ FWYIP  LRG
Sbjct: 286 WMTWKGLGEKGMSDYVERAFENSEYLTQKLREREGFRLVLP-KFECTNISFWYIPPCLRG 462

Query: 524 VPDSPERREKLHRVAPKIKALMMESGTTMVGYQPQGDK--ANFFRMVISNPAATQSDIDF 581
             ++ +   K+ +VAP IK  MM  GT M+GYQP   K   NFFR++I+N  +  +D+DF
Sbjct: 463 KEETADWWNKVAKVAPVIKKRMMLEGTMMIGYQPLTSKNWVNFFRVIIANSLSDFTDMDF 642

Query: 582 LIEEIERL 589
           +++EI+RL
Sbjct: 643 IVDEIDRL 666

 Score = 50.8 bits (120), Expect(2) = 1e-55,   Method: Compositional matrix adjust.
 Identities = 19/32 (59%), Positives = 28/32 (87%)
 Frame = +3

Query: 370 HVDAAWGGGLLMSRKHRHKLSGIERANSVTWN 401
           H+D AWGGG L+S+K+RH ++G+E+A+SV WN
Sbjct: 3   HIDCAWGGGALLSKKYRHLMNGVEKADSVAWN 98
>22458
          Length = 523

 Score = 71.2 bits (173), Expect(2) = 5e-21,   Method: Composition-based stats.
 Identities = 32/67 (47%), Positives = 45/67 (67%)
 Frame = +3

Query: 134 STKVLDFHHPHQLLEGMEGFNLELSDHPESLEQILVDCRDTLKYGVRTGHPRFFNQLSTG 193
           ++KV+DF HP  L   ++   L LSD P   ++++  CRD +KY V+TGHP FFNQL  G
Sbjct: 210 ASKVVDFKHPEDLRTTLD---LTLSDQPADNDRLMDACRDIIKYSVKTGHPHFFNQLFGG 380

Query: 194 LDIIGLA 200
           +D+ GLA
Sbjct: 381 MDLYGLA 401

 Score = 48.5 bits (114), Expect(2) = 5e-21,   Method: Composition-based stats.
 Identities = 19/40 (47%), Positives = 28/40 (70%)
 Frame = +2

Query: 201 GEWLTSTANTNMFTYEIAPVFVLMEQITLKKMREIVGWSN 240
           G WLT   NT+ +T+E+APVF LME + L +M + +G+ N
Sbjct: 404 GSWLTEALNTSSYTFEVAPVFTLMENVVLGEMLKHIGFPN 523
>11435
          Length = 477

 Score = 89.4 bits (220), Expect = 4e-18,   Method: Composition-based stats.
 Identities = 45/102 (44%), Positives = 62/102 (60%), Gaps = 1/102 (0%)
 Frame = -1

Query: 110 EQTAQFLLEVVDILLNY-VRKTFDRSTKVLDFHHPHQLLEGMEGFNLELSDHPESLEQIL 168
           EQ   FL E+V +++   +R+      KV+DF HP  L   ++   L LSD P   ++++
Sbjct: 297 EQGYHFLSELVPLIIQQALREGTSAHNKVVDFKHPEDLRTTLD---LTLSDQPADNDRLM 127

Query: 169 VDCRDTLKYGVRTGHPRFFNQLSTGLDIIGLAGEWLTSTANT 210
             CRD +KY V+TGHP FFNQL  G+D+ GLAG WLT   NT
Sbjct: 126 DACRDIIKYSVKTGHPHFFNQLFGGMDLYGLAGSWLTEALNT 1
>20610
          Length = 928

 Score = 32.0 bits (71), Expect = 0.64,   Method: Compositional matrix adjust.
 Identities = 12/32 (37%), Positives = 22/32 (68%)
 Frame = +1

Query: 349 YGAFDPIQEIADICEKYNLWLHVDAAWGGGLL 380
           +G  D ++ +A + +KYN+ +HVD+  GG L+
Sbjct: 760 HGIIDDVEAVAALGKKYNIPVHVDSCLGGFLV 855
>30109
          Length = 1083

 Score = 31.6 bits (70), Expect = 0.94,   Method: Compositional matrix adjust.
 Identities = 21/73 (28%), Positives = 35/73 (47%)
 Frame = -3

Query: 220 VFVLMEQITLKKMREIVGWSNKDGDGIFSPGGAISNMYSIMAARYKYFPEVKTKGMAAVP 279
           +++L+E+ITL  +  I  WS  D   IF+ G A +N   +           K+  +A + 
Sbjct: 988 IYMLLEEITLTGLF*IYSWSKSDSYIIFNLGSAKTNCVRM---------SCKSIDLAKIR 836

Query: 280 KLVLFTSEHSHYS 292
            +V F S  S +S
Sbjct: 835 LVV*FASFKSRFS 797
>13106
          Length = 1162

 Score = 31.2 bits (69), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 12/32 (37%), Positives = 22/32 (68%)
 Frame = -3

Query: 349 YGAFDPIQEIADICEKYNLWLHVDAAWGGGLL 380
           +G  D ++ +A + +KYN+ +HVD+  GG L+
Sbjct: 941 HGIIDDVEAVAALGKKYNIPVHVDSCLGGFLV 846
>23871
          Length = 890

 Score = 29.6 bits (65), Expect = 4.0,   Method: Compositional matrix adjust.
 Identities = 11/27 (40%), Positives = 19/27 (70%)
 Frame = -2

Query: 429 MCAGYLFQPDKQYDVSYDTGDKAIQCG 455
           +C+G LFQ +KQ ++S  +G+  +Q G
Sbjct: 889 VCSGLLFQ*NKQTNISQXSGEPTLQLG 809
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|7106301|ref|NP_031922.1| microtubule-associated
protein, RP/EB family, member 1 [Mus musculus]
         (268 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

02149                                                                 285   2e-77
06997                                                                  73   1e-13
09949                                                                  67   7e-12
28710                                                                  66   1e-11
05935                                                                  27   7.8  
29034                                                                  27   10.0 
>02149
          Length = 1269

 Score =  285 bits (729), Expect = 2e-77,   Method: Compositional matrix adjust.
 Identities = 146/259 (56%), Positives = 186/259 (71%), Gaps = 5/259 (1%)
 Frame = +3

Query: 1   MAVNVYSTSVTSDNLSRHDMLAWINESLQLNLTKIEQLCSGAAYCQFMDMLFPGSIALKK 60
           MAVNV+STS TSDNLSRHD++AW+N+SLQ +  KIE+LC+GAAYCQFMDMLFPG++ALKK
Sbjct: 69  MAVNVHSTSCTSDNLSRHDIIAWVNDSLQTSYGKIEELCTGAAYCQFMDMLFPGTLALKK 248

Query: 61  VKFQAKLEHEYIQNFKILQAGFKRMGVDKIIPVDKLVKGKFQDNFEFVQWFKKFFDANYD 120
            KF  KLEHEYIQNFK+LQ  F ++GVDK+IPV++LVKG+FQDNFEFVQWFK+FFDAN  
Sbjct: 249 AKFNTKLEHEYIQNFKLLQNNFGKLGVDKVIPVERLVKGRFQDNFEFVQWFKRFFDANNK 428

Query: 121 GKEYDPVAARQGQETAVAPSLVAPALSKPKKPLGSSTAAPQRPIATQRTTAAPKAGPG-- 178
           G +YDP++AR G+    A      AL+K      + TA P+  +   RTT A  A     
Sbjct: 429 GLDYDPLSARGGEPMGGANK---GALNKAP---SNRTAPPKTRVPPSRTTPARPAANNVR 590

Query: 179 --MVRKNPGVGNGDDEAAE-LMQQVKVLKLTVEDLEKERDFYFGKLRNIELICQENEGEN 235
             M +       GD    E L  +++ L +  E LEKERDFYFGKLR+IE+ICQE+  E+
Sbjct: 591 SPMSKPTSNHAAGDSPMVEDLRAELRQLTVEKEGLEKERDFYFGKLRDIEVICQEH--ED 764

Query: 236 DPVLQRIVDILYATDEGFV 254
           D  ++ I+DILYAT++GF 
Sbjct: 765 DVSMKAIMDILYATEDGFA 821
>06997
          Length = 583

 Score = 72.8 bits (177), Expect = 1e-13,   Method: Compositional matrix adjust.
 Identities = 36/64 (56%), Positives = 50/64 (78%)
 Frame = +1

Query: 190 DDEAAELMQQVKVLKLTVEDLEKERDFYFGKLRNIELICQENEGENDPVLQRIVDILYAT 249
           +D  AE+  Q++ L +  E LEKERDFYFGKLR+IE+ICQE+  E+D  ++ I+DILYAT
Sbjct: 76  EDLRAEVCAQLRQLTVEKEGLEKERDFYFGKLRDIEVICQEH--EDDVSMKAIMDILYAT 249

Query: 250 DEGF 253
           ++GF
Sbjct: 250 EDGF 261
>09949
          Length = 455

 Score = 67.0 bits (162), Expect = 7e-12,   Method: Compositional matrix adjust.
 Identities = 33/59 (55%), Positives = 47/59 (79%)
 Frame = -1

Query: 195 ELMQQVKVLKLTVEDLEKERDFYFGKLRNIELICQENEGENDPVLQRIVDILYATDEGF 253
           +L  +++ L +  E LEKERDFYFGKLR+IE+ICQE+  E+D  ++ I+DILYAT++GF
Sbjct: 443 DLRAELRQLTVEKEGLEKERDFYFGKLRDIEVICQEH--EDDVSMKAIMDILYATEDGF 273
>28710
          Length = 525

 Score = 66.2 bits (160), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 32/59 (54%), Positives = 46/59 (77%)
 Frame = -1

Query: 195 ELMQQVKVLKLTVEDLEKERDFYFGKLRNIELICQENEGENDPVLQRIVDILYATDEGF 253
           +L  +++ + L  E LEKERDFYFGKLR+IE+ICQE+  E+   ++ I+DILYAT++GF
Sbjct: 507 DLRAELRQMNLEKEGLEKERDFYFGKLRDIEIICQEH--EDSDTMKGILDILYATEDGF 337
>05935
          Length = 1181

 Score = 26.9 bits (58), Expect = 7.8,   Method: Compositional matrix adjust.
 Identities = 11/21 (52%), Positives = 16/21 (76%)
 Frame = +3

Query: 196 LMQQVKVLKLTVEDLEKERDF 216
           L+  +K+ KLTVE +E+ERD 
Sbjct: 516 LLLYIKITKLTVETIERERDM 578
>29034
          Length = 642

 Score = 26.6 bits (57), Expect = 10.0,   Method: Compositional matrix adjust.
 Identities = 17/51 (33%), Positives = 23/51 (45%)
 Frame = -3

Query: 102 QDNFEFVQWFKKFFDANYDGKEYDPVAARQGQETAVAPSLVAPALSKPKKP 152
           QD    V   K   D +   KE D V   +GQ + V+PSL     ++P  P
Sbjct: 568 QDGSVVVSEEKNTADLSLSPKEADIVNVSEGQTSCVSPSLEDKDTTEPDYP 416
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|9790015|ref|NP_062744.1| transmembrane emp24 domain
trafficking protein 2 [Mus musculus]
         (201 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

19964                                                                 284   2e-77
38580                                                                  76   3e-16
03595                                                                  63   8e-11
>19964
          Length = 901

 Score =  284 bits (727), Expect = 2e-77,   Method: Compositional matrix adjust.
 Identities = 130/170 (76%), Positives = 155/170 (91%), Gaps = 2/170 (1%)
 Frame = +2

Query: 34  FERVTSGTKMGLIFEVAEGGFLDIDVEITGPDNKGIYKGDRESSGKYTFAAHMDGTYKFC 93
           F++V+SGTKM L+FEVAEGGFLDIDV+I GPDNK I++G+RES+GKYTFAAHMDG YK+C
Sbjct: 2   FDKVSSGTKMSLMFEVAEGGFLDIDVKIYGPDNKVIHQGERESNGKYTFAAHMDGIYKYC 181

Query: 94  FSNRMSTMTPKIVMFTIDIGEAPKGQ--DMETEAHQNKLEEMINELAVAMTAVKHEQEYM 151
           FSN+MSTMTPK+VMF++D+GE PK Q  D +++A   KLEEM+N+L+ A+T  KHEQEYM
Sbjct: 182 FSNQMSTMTPKVVMFSMDVGEKPKDQDGDKDSDASHGKLEEMVNQLSTALTGAKHEQEYM 361

Query: 152 EVRERIHRAINDNTNSRVVLWSFFEALVLVAMTLGQIYYLKRFFEVRRVV 201
           EVRERIHRAINDNTNSRVVLW+FFEALVLVAM+LGQ+YYLKRFFEVRRVV
Sbjct: 362 EVRERIHRAINDNTNSRVVLWAFFEALVLVAMSLGQVYYLKRFFEVRRVV 511
>38580
          Length = 727

 Score = 75.9 bits (185), Expect(2) = 3e-16,   Method: Compositional matrix adjust.
 Identities = 45/142 (31%), Positives = 71/142 (50%), Gaps = 2/142 (1%)
 Frame = +1

Query: 32  CFFERVTSGTKMGLIFEVAEGGFLDIDVEITGPDNKGIYKGDRESSGKYTFAAHMDGTYK 91
           CF E V  G K  + ++V  GG  D+D+E+T P  + +YK  ++    +T+ A + G + 
Sbjct: 184 CFHELVDKGVKATIEYQVVMGGNYDVDMELTAPTGQVLYKEVKKQYDSFTWTADVKGIHA 363

Query: 92  FCFSNRMSTMTPKIVMFTIDIG-EAPKGQ-DMETEAHQNKLEEMINELAVAMTAVKHEQE 149
           FCFSN  ST T K+V F + +G + P G  D +       +E     L   +  V   Q 
Sbjct: 364 FCFSNEFSTFTHKVVYFDLQVGDDKPVGDTDGDHVTAMTSIENSAVNLFEELKRVLDLQT 543

Query: 150 YMEVRERIHRAINDNTNSRVVL 171
           +  +RE   RA  ++ N RV+ 
Sbjct: 544 HFRLREAQGRAFAEDVNERVLF 609

 Score = 25.4 bits (54), Expect(2) = 3e-16,   Method: Compositional matrix adjust.
 Identities = 10/25 (40%), Positives = 18/25 (72%)
 Frame = +3

Query: 171 LWSFFEALVLVAMTLGQIYYLKRFF 195
           +WS  E++++V + +GQI  L+ FF
Sbjct: 606 VWSVGESILIVLIGIGQILVLRSFF 680
>03595
          Length = 1492

 Score = 62.8 bits (151), Expect = 8e-11,   Method: Compositional matrix adjust.
 Identities = 36/128 (28%), Positives = 64/128 (50%), Gaps = 4/128 (3%)
 Frame = +3

Query: 78  GKYTFAAHMDGTYKFCF-SNRMSTMTPKIVMFTIDIGEAPKGQDMETEAHQNKLEEM--- 133
           G++TF +H  G +  C  SN  + +    +   +DI       D +    ++KL E+   
Sbjct: 75  GRFTFTSHSAGEHIICLNSNSTAWLYAGQLRVHLDISVGEHAVDYQQVQAKDKLSELQLR 254

Query: 134 INELAVAMTAVKHEQEYMEVRERIHRAINDNTNSRVVLWSFFEALVLVAMTLGQIYYLKR 193
           I +L   +  +  EQ Y   RE   R  +++TN RV+ WS  + L+L+     Q+ +LK 
Sbjct: 255 IRQLLDQVEQITKEQNYQRYREERFRQTSESTNHRVLWWSIAQTLILLLTGFWQMQHLKS 434

Query: 194 FFEVRRVV 201
           FF+ +++V
Sbjct: 435 FFQAKKLV 458
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|10946604|ref|NP_067280.1| Sec61, alpha subunit 2 [Mus
musculus]
         (476 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

11779                                                                 284   4e-77
29817                                                                 258   4e-69
05072                                                                 204   8e-53
26212                                                                 202   3e-52
03057                                                                  65   6e-11
>11779
          Length = 460

 Score =  284 bits (727), Expect = 4e-77,   Method: Compositional matrix adjust.
 Identities = 136/153 (88%), Positives = 146/153 (95%)
 Frame = -2

Query: 160 LIVLLLDELLQKGYGLGSGISLFIATNICETIVWKAFSPTTINTGRGTEFEGAVIALFHL 219
           +IVLLLDELLQKGYGLGSGISLFIATNICETI+WKA SP T+NTGRGTEFEGA+IALFHL
Sbjct: 459 IIVLLLDELLQKGYGLGSGISLFIATNICETIMWKALSPATVNTGRGTEFEGALIALFHL 280

Query: 220 LATRTDKVRALREAFYRQNLPNLMNLIATVFVFAVVIYFQGFRVDLPIKSARYRGQYSSY 279
           LATR DKVR LREAFYRQNLPNLMNL+ATV VFA+VIYFQGFRVDLPIKSARYRGQ +SY
Sbjct: 279 LATRQDKVRGLREAFYRQNLPNLMNLMATVLVFAIVIYFQGFRVDLPIKSARYRGQQTSY 100

Query: 280 PIKLFYTSNIPIILQSALVSNLYVISQMLSVRF 312
           PIKLFYTSNIPIILQSALVSNLY+ISQML+ +F
Sbjct: 99  PIKLFYTSNIPIILQSALVSNLYIISQMLAAKF 1
>29817
          Length = 551

 Score =  258 bits (658), Expect = 4e-69,   Method: Compositional matrix adjust.
 Identities = 120/140 (85%), Positives = 131/140 (93%)
 Frame = +2

Query: 337 PVGGLCYYLSPPESMGAIFEDPVHVVVYIIFMLGSCAFFSKTWIEVSGSSAKDVAKQLKE 396
           PVGGLCYYLSPPE++G + EDP+H V+YI+FMLGSCAFFSKTWI+VSGSSAKDVAKQLKE
Sbjct: 2   PVGGLCYYLSPPETLGHVLEDPIHAVLYIVFMLGSCAFFSKTWIDVSGSSAKDVAKQLKE 181

Query: 397 QQMVMRGHRDTSMVHELNRYIPTAAAFGGLCIGALSVLADFLGAIGSGTGILLAVTIIYQ 456
           QQMVMRGHR+ SM+ ELNRYIPTAAAFGGLCIGALSVLADFLGAIGSGTGILLAVTIIYQ
Sbjct: 182 QQMVMRGHREQSMIKELNRYIPTAAAFGGLCIGALSVLADFLGAIGSGTGILLAVTIIYQ 361

Query: 457 YFEIFVKEQAEVGGMGALFF 476
           YFE FVKEQ+E+GGM  L F
Sbjct: 362 YFEYFVKEQSEMGGMSTLLF 421
>05072
          Length = 1404

 Score =  204 bits (518), Expect = 8e-53,   Method: Compositional matrix adjust.
 Identities = 100/119 (84%), Positives = 108/119 (90%), Gaps = 1/119 (0%)
 Frame = +3

Query: 359 VHVVVYIIFMLGSCAFFSKTWIEVSGSSAKDVAKQLKEQQMVMRG-HRDTSMVHELNRYI 417
           +H V+YI+FMLGSCAFFSKTWI+VSGSSAKDVAKQLKEQQMV  G  R+ SM+ ELNRYI
Sbjct: 3   IHAVLYIVFMLGSCAFFSKTWIDVSGSSAKDVAKQLKEQQMVNEGVTREKSMIKELNRYI 182

Query: 418 PTAAAFGGLCIGALSVLADFLGAIGSGTGILLAVTIIYQYFEIFVKEQAEVGGMGALFF 476
           PTAAAFGGLCIGALSVLADFLGAIGSGTGILLAVTIIYQYFE FVKEQ+E+GGM  L F
Sbjct: 183 PTAAAFGGLCIGALSVLADFLGAIGSGTGILLAVTIIYQYFEYFVKEQSEMGGMSTLLF 359
>26212
          Length = 415

 Score =  202 bits (513), Expect = 3e-52,   Method: Compositional matrix adjust.
 Identities = 95/105 (90%), Positives = 102/105 (97%)
 Frame = -1

Query: 2   GIKFLEVIKPFCAVLPEIQKPERKIQFREKVLWTAITLFIFLVCCQIPLFGIMSSDSADP 61
           G+KFLE +KPFC+VLPEI KP+RKIQFREKVLWTAITLFIFL+CCQIPLFGI+SSDSADP
Sbjct: 316 GLKFLEFVKPFCSVLPEIAKPDRKIQFREKVLWTAITLFIFLICCQIPLFGIVSSDSADP 137

Query: 62  FYWMRVILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVGDTP 106
           FYW+RVILASNRGTLMELGISPIVTS LIMQLLAGAKIIEVGDTP
Sbjct: 136 FYWIRVILASNRGTLMELGISPIVTSSLIMQLLAGAKIIEVGDTP 2
>03057
          Length = 2342

 Score = 65.1 bits (157), Expect = 6e-11,   Method: Compositional matrix adjust.
 Identities = 32/38 (84%), Positives = 34/38 (89%)
 Frame = +1

Query: 439 GAIGSGTGILLAVTIIYQYFEIFVKEQAEVGGMGALFF 476
           GAIGSGTGILLAVTIIYQYFE FVKEQ+E+GGM  L F
Sbjct: 142 GAIGSGTGILLAVTIIYQYFEYFVKEQSEMGGMSTLLF 255
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|34486094|ref|NP_038535.2| eukaryotic translation
initiation factor 4, gamma 2 isoform 1 [Mus musculus]
         (906 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

04759                                                                 285   4e-77
16157                                                                 209   5e-54
10296                                                                  88   3e-33
30336                                                                  90   1e-31
14839                                                                 117   3e-26
17532                                                                  60   3e-09
11597                                                                  55   2e-07
05432                                                                  39   0.007
33784                                                                  31   1.8  
>04759
          Length = 2827

 Score =  285 bits (730), Expect = 4e-77,   Method: Compositional matrix adjust.
 Identities = 137/336 (40%), Positives = 208/336 (61%)
 Frame = +2

Query: 550  VVTDYLNSGNANDAVSGVREMRAPKHFLPEMLSKVIILSLDRSDEDKEKASSLISLLKQE 609
            ++T++  + + N  V+ ++E+  PK  + + LS+V+I S++RS+ ++++   L++ LK +
Sbjct: 1574 LLTEFFTNQDMNKTVTAIKELHMPKMMVADFLSQVLIGSVNRSEAEQDEVMKLVAALKMD 1753

Query: 610  GIATSDNFMQAFLNVLEQCPKLEVDIPLVKSYLAQFAARAIISELVSISELAQPLESGTH 669
               TSD F++ F  V +Q   LE + PL+KS++A+F A+A+  E+ S++ELAQP + G H
Sbjct: 1754 KTITSDQFIEXFTRVADQMSALEQETPLIKSHMARFGAQALSCEVSSLTELAQPFQGGVH 1933

Query: 670  FPXXXXXXXXXXXXXDREWLTELFQQSKVNMQKMLPEIDQNKDRMLEILEXXXXXXXXXX 729
            +P             D+ WL +LF QS +N+Q MLPEIDQ K+RM+EILE          
Sbjct: 1934 YPLFLLCLQAAHRLHDKSWLVKLFNQSNLNLQDMLPEIDQKKERMMEILEDRGLSFLFPL 2113

Query: 730  XXXXXXXXXXXXXDPSPQTIYKWIKDNISPKLHVDKGFVNILMTSFLQYISSEVSPPSDE 789
                         +PS   I+KWIK+ + P L  +  F+NIL+   ++YI+ E S  ++ 
Sbjct: 2114 LRVQSELGRQIAAEPSAGAIFKWIKERVDPDLFANPNFINILVAGVVKYITGE-STLAEN 2290

Query: 790  TDSSSAPSXXXXXXXXXXXXSFKPVMQKFLHDHVDLQVSALYALQVHCYNSSFPKGMLLR 849
             D +  P               K V+QKFLH+H+DLQVSALYA+QV C++  FPKGMLLR
Sbjct: 2291 ADPNVTPDKSLMDKEKELLDKLKGVLQKFLHEHIDLQVSALYAVQVFCHSHHFPKGMLLR 2470

Query: 850  FFVHFYDMEIIEEEAFLAWKEDITQEFPGKGKALFQ 885
            FFV+ YD EI+EEEAFL WKE++  ++PGKGKALF+
Sbjct: 2471 FFVNLYDQEIVEEEAFLHWKEEVNDQYPGKGKALFR 2578
>16157
          Length = 1330

 Score =  209 bits (531), Expect = 5e-54,   Method: Compositional matrix adjust.
 Identities = 103/225 (45%), Positives = 138/225 (61%)
 Frame = -1

Query: 664  LESGTHFPXXXXXXXXXXXXXDREWLTELFQQSKVNMQKMLPEIDQNKDRMLEILEXXXX 723
             + G H+P             D++WLT +F  SK+++  MLPEIDQ K+++LEILE    
Sbjct: 1330 FQHGVHYPLFLLCLQAAHRVKDKQWLTRVFSDSKLDLITMLPEIDQKKEKLLEILEDRGL 1151

Query: 724  XXXXXXXXXXXXXXXXXXXDPSPQTIYKWIKDNISPKLHVDKGFVNILMTSFLQYISSEV 783
                               +P+    +KWIKD++ P L  +  F++IL+TS ++YI+SE 
Sbjct: 1150 SFLFPLMRVQSELGRHIAAEPTASATFKWIKDHVDPDLFTNPKFIHILVTSVVKYITSE- 974

Query: 784  SPPSDETDSSSAPSXXXXXXXXXXXXSFKPVMQKFLHDHVDLQVSALYALQVHCYNSSFP 843
            S  ++  DSS+AP               K V+QKFLH+H+ LQVSALYA+QV C++  FP
Sbjct: 973  STLAENVDSSAAPDKAASDKEKELLDKLKGVLQKFLHEHLSLQVSALYAVQVFCHSHHFP 794

Query: 844  KGMLLRFFVHFYDMEIIEEEAFLAWKEDITQEFPGKGKALFQVNQ 888
            KGMLLRFFV+ YD EIIEEEAFL WKE++  EFPGKGK LFQVNQ
Sbjct: 793  KGMLLRFFVNLYDQEIIEEEAFLHWKEEVNDEFPGKGKXLFQVNQ 659
>10296
          Length = 1682

 Score = 87.8 bits (216), Expect(2) = 3e-33,   Method: Compositional matrix adjust.
 Identities = 47/139 (33%), Positives = 73/139 (52%), Gaps = 5/139 (3%)
 Frame = +1

Query: 663  PLESGTHFPXXXXXXXXXXXXXDREWLTELFQQSKVNMQKMLP-----EIDQNKDRMLEI 717
            P + G H+P             D++WLT +F  SK+++  MLP     EIDQ K+++LEI
Sbjct: 1240 PFQHGVHYPLFLLCLQAAHRVKDKQWLTRVFSDSKLDLITMLPDTLSTEIDQKKEKLLEI 1419

Query: 718  LEXXXXXXXXXXXXXXXXXXXXXXXDPSPQTIYKWIKDNISPKLHVDKGFVNILMTSFLQ 777
            LE                       +P+    +KWIKD++ P L  +  F++IL+TS ++
Sbjct: 1420 LEDRGLSFLFPLMRVQSELGRHIAAEPTASATFKWIKDHVDPDLFTNPKFIHILVTSVVK 1599

Query: 778  YISSEVSPPSDETDSSSAP 796
            YI+SE S  ++  DSS+AP
Sbjct: 1600 YITSE-STLAENVDSSAAP 1653

 Score = 73.2 bits (178), Expect(2) = 3e-33,   Method: Compositional matrix adjust.
 Identities = 35/114 (30%), Positives = 68/114 (59%)
 Frame = +2

Query: 550  VVTDYLNSGNANDAVSGVREMRAPKHFLPEMLSKVIILSLDRSDEDKEKASSLISLLKQE 609
            +V D+    +  +  S ++ +R P+  + ++L+  +I S+ R++ D++K   LIS LK +
Sbjct: 902  LVRDFFTKEDVTETASAIKALRLPQGMVHDLLAHFLISSISRTESDQDKVMELISTLKTD 1081

Query: 610  GIATSDNFMQAFLNVLEQCPKLEVDIPLVKSYLAQFAARAIISELVSISELAQP 663
             +  S++FM+    V +Q   LE + P VKS++A+F A+A+   + ++ ELA P
Sbjct: 1082 KVIVSEHFMEGLQKVADQMSALEQETPRVKSHVARFGAQALALGVSNLLELAAP 1243
>30336
          Length = 388

 Score = 89.7 bits (221), Expect(2) = 1e-31,   Method: Composition-based stats.
 Identities = 40/73 (54%), Positives = 54/73 (73%)
 Frame = -3

Query: 258 MRTVGPRLDHERAKSLMDQYFARMCSLMLSKELPARIRFLLQDTVELREHHWVPRKAFLD 317
           +RTVGPRLD  +AK+LM QYF R+    ++++L  RIRF+LQD +ELR + W PR+   +
Sbjct: 260 IRTVGPRLDTPKAKALMKQYFVRIEVFAVNEDLTPRIRFMLQDVIELRANEWKPRRVATE 81

Query: 318 NGPKTINQIRQDA 330
           NGPKTI  IRQ+A
Sbjct: 80  NGPKTITAIRQEA 42

 Score = 66.6 bits (161), Expect(2) = 1e-31,   Method: Compositional matrix adjust.
 Identities = 31/43 (72%), Positives = 37/43 (86%)
 Frame = -1

Query: 215 GELGKLDLIHESILHKCIKTLLEKKKRVQLKDMGEDLECLCQI 257
           GELGKLD+++E ILHKCI+ LLEKKK   L+DM ED+ECLCQI
Sbjct: 388 GELGKLDMLYEGILHKCIQQLLEKKKNTPLRDMEEDMECLCQI 260
>14839
          Length = 340

 Score =  117 bits (292), Expect = 3e-26,   Method: Composition-based stats.
 Identities = 51/67 (76%), Positives = 58/67 (86%)
 Frame = +3

Query: 822 HVDLQVSALYALQVHCYNSSFPKGMLLRFFVHFYDMEIIEEEAFLAWKEDITQEFPGKGK 881
           H+ LQVSALYA+QV C++  FPKGMLLRFFV+ YD EIIEEEAFL WKE++  EFPGKGK
Sbjct: 3   HLSLQVSALYAVQVFCHSHHFPKGMLLRFFVNLYDQEIIEEEAFLHWKEEVNDEFPGKGK 182

Query: 882 ALFQVNQ 888
           ALFQVNQ
Sbjct: 183 ALFQVNQ 203
>17532
          Length = 432

 Score = 60.5 bits (145), Expect = 3e-09,   Method: Composition-based stats.
 Identities = 27/56 (48%), Positives = 35/56 (62%)
 Frame = -3

Query: 833 LQVHCYNSSFPKGMLLRFFVHFYDMEIIEEEAFLAWKEDITQEFPGKGKALFQVNQ 888
           +QV C++  FPKGMLLRF         +       WKE++  ++PGKGKALFQVNQ
Sbjct: 430 VQVFCHSHHFPKGMLLRFLSTCTTRRSLRRRLSSNWKEEVNDQYPGKGKALFQVNQ 263
>11597
          Length = 2290

 Score = 54.7 bits (130), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 30/98 (30%), Positives = 50/98 (51%), Gaps = 19/98 (19%)
 Frame = +2

Query: 255 CQIMRTVGPRLDHERAKSLMDQYF---ARMCSLMLSKE----------------LPARIR 295
            +++ T+G  LDH +AK+ MDQYF    +M S + + +                L  R++
Sbjct: 2   TKLLDTIGGELDHPKAKTRMDQYFQQLEKMTSDLTAAQQSATGHMPKSKDPKDKLSTRVK 181

Query: 296 FLLQDTVELREHHWVPRKAFLDNGPKTINQIRQDAVKD 333
           F + D +ELR + WV R+    N P T+ +I Q A ++
Sbjct: 182 FGILDIIELRRNRWVKRRIHAQNMPTTLTEIHQKAKQE 295
>05432
          Length = 1122

 Score = 39.3 bits (90), Expect = 0.007,   Method: Composition-based stats.
 Identities = 14/26 (53%), Positives = 20/26 (76%)
 Frame = +1

Query: 851  FVHFYDMEIIEEEAFLAWKEDITQEF 876
             V+ YD EI+EEEAFL WKE++  ++
Sbjct: 1045 LVNLYDQEIVEEEAFLHWKEEVNDQY 1122
>33784
          Length = 594

 Score = 31.2 bits (69), Expect = 1.8,   Method: Composition-based stats.
 Identities = 20/50 (40%), Positives = 25/50 (50%), Gaps = 9/50 (18%)
 Frame = +3

Query: 589 LDRSDEDKEKASSLISLLK------QEGIATSDNFMQAFL---NVLEQCP 629
           L+ S ED ++  S + LL       QEGI   DNF+ AFL   N    CP
Sbjct: 228 LNHSPEDTQENESFLKLLVDLIDFLQEGIPVVDNFLAAFLHTWNGSNYCP 377
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|39930509|ref|NP_579928.1| APC-binding protein EB2
[Mus musculus]
         (281 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

02149                                                                 283   4e-77
28710                                                                  79   3e-15
06997                                                                  75   2e-14
09949                                                                  75   4e-14
16231                                                                  30   0.75 
13383                                                                  27   8.0  
>02149
          Length = 1269

 Score =  283 bits (725), Expect = 4e-77,   Method: Compositional matrix adjust.
 Identities = 147/267 (55%), Positives = 178/267 (66%), Gaps = 2/267 (0%)
 Frame = +3

Query: 1   MAVNVYSTSVTSENLSRHDMLAWVNDSLHLNYTKIEQLCSGAAYCQFMDMLFPGCVHLRK 60
           MAVNV+STS TS+NLSRHD++AWVNDSL  +Y KIE+LC+GAAYCQFMDMLFPG + L+K
Sbjct: 69  MAVNVHSTSCTSDNLSRHDIIAWVNDSLQTSYGKIEELCTGAAYCQFMDMLFPGTLALKK 248

Query: 61  VKFQAKLEHEYIHNFKVLQAAFKKMGVDKIIPVEKLVKGKFQDNFEFIQWFKKFFDANYD 120
            KF  KLEHEYI NFK+LQ  F K+GVDK+IPVE+LVKG+FQDNFEF+QWFK+FFDAN  
Sbjct: 249 AKFNTKLEHEYIQNFKLLQNNFGKLGVDKVIPVERLVKGRFQDNFEFVQWFKRFFDANNK 428

Query: 121 GKDYNPLLARQGQDVAPPPNPGDQIFNKSKKLIGTAVPQRTSPTGPKNMQTSGRLSNVAP 180
           G DY+PL AR G+ +             +K  +  A   RT+P  PK      R +   P
Sbjct: 429 GLDYDPLSARGGEPMG----------GANKGALNKAPSNRTAP--PKTRVPPSRTTPARP 572

Query: 181 PCILRKNPPSARNGGHEADAXXXXXXXXXXXXXXTV--DGLEKERDFYFSKLRDIELICQ 238
                ++P S     H A                TV  +GLEKERDFYF KLRDIE+ICQ
Sbjct: 573 AANNVRSPMSKPTSNHAAGDSPMVEDLRAELRQLTVEKEGLEKERDFYFGKLRDIEVICQ 752

Query: 239 EHESENSPVISGIIGILYATEEGFAPP 265
           EHE + S  +  I+ ILYATE+GFAPP
Sbjct: 753 EHEDDVS--MKAIMDILYATEDGFAPP 827
>28710
          Length = 525

 Score = 78.6 bits (192), Expect = 3e-15,   Method: Compositional matrix adjust.
 Identities = 36/49 (73%), Positives = 42/49 (85%)
 Frame = -1

Query: 217 DGLEKERDFYFSKLRDIELICQEHESENSPVISGIIGILYATEEGFAPP 265
           +GLEKERDFYF KLRDIE+ICQEH  E+S  + GI+ ILYATE+GFAPP
Sbjct: 468 EGLEKERDFYFGKLRDIEIICQEH--EDSDTMKGILDILYATEDGFAPP 328
>06997
          Length = 583

 Score = 75.5 bits (184), Expect = 2e-14,   Method: Compositional matrix adjust.
 Identities = 35/49 (71%), Positives = 41/49 (83%)
 Frame = +1

Query: 217 DGLEKERDFYFSKLRDIELICQEHESENSPVISGIIGILYATEEGFAPP 265
           +GLEKERDFYF KLRDIE+ICQEHE + S  +  I+ ILYATE+GFAPP
Sbjct: 130 EGLEKERDFYFGKLRDIEVICQEHEDDVS--MKAIMDILYATEDGFAPP 270
>09949
          Length = 455

 Score = 74.7 bits (182), Expect = 4e-14,   Method: Compositional matrix adjust.
 Identities = 35/49 (71%), Positives = 41/49 (83%)
 Frame = -1

Query: 217 DGLEKERDFYFSKLRDIELICQEHESENSPVISGIIGILYATEEGFAPP 265
           +GLEKERDFYF KLRDIE+ICQEHE + S  +  I+ ILYATE+GFAPP
Sbjct: 404 EGLEKERDFYFGKLRDIEVICQEHEDDVS--MKAIMDILYATEDGFAPP 264
>16231
          Length = 1393

 Score = 30.4 bits (67), Expect = 0.75,   Method: Compositional matrix adjust.
 Identities = 18/55 (32%), Positives = 21/55 (38%)
 Frame = -2

Query: 3    VNVYSTSVTSENLSRHDMLAWVNDSLHLNYTKIEQLCSGAAYCQFMDMLFPGCVH 57
            V  Y TS     LSRH + AW   S+      +  L S          L PG VH
Sbjct: 1161 VGRYHTSADPSPLSRHSI*AWEGPSMEKPRAPVSPLVSTVKRPSAAPPLLPGRVH 997
>13383
          Length = 1072

 Score = 26.9 bits (58), Expect = 8.0,   Method: Compositional matrix adjust.
 Identities = 12/34 (35%), Positives = 18/34 (52%)
 Frame = -3

Query: 17  RHDMLAWVNDSLHLNYTKIEQLCSGAAYCQFMDM 50
           RH +    N   H N+ KI + CS    CQ++D+
Sbjct: 536 RHSLRTIANSLFHCNF-KIRRFCSFLLRCQWLDV 438
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|42734465|ref|NP_081590.2| membrane-associated ring
finger (C3HC4) 5 [Mus musculus]
         (278 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

20951                                                                 219   4e-77
06740                                                                  34   0.054
14294                                                                  33   0.18 
00275                                                                  29   2.7  
>20951
          Length = 627

 Score =  219 bits (559), Expect(2) = 4e-77,   Method: Compositional matrix adjust.
 Identities = 97/131 (74%), Positives = 118/131 (90%)
 Frame = -1

Query: 54  KQRGNSTARVACPQCNAEYLIVFPKLGPVVYALDLADRLISKACPFAAAGIMVGSIYWTA 113
           KQ+GN TA+VACPQCN EY+I+FP+LG +V  +DLAD++I K CPF A G+ +GS+YWTA
Sbjct: 411 KQKGNGTAKVACPQCNTEYIIIFPELGYIVSVMDLADKIIYKTCPFVAGGMFIGSVYWTA 232

Query: 114 VTYGAVTVMQVVGHKEGLDVMERADPLFLLIGLPTIPVMLILGKMIRWEDYVLRLWRKYS 173
           VTYGAVTVMQV+GHKEGL+VMERADPLFLLIGLPTIP+MLILGKM+RWEDY+LRLWRK+S
Sbjct: 231 VTYGAVTVMQVLGHKEGLNVMERADPLFLLIGLPTIPIMLILGKMVRWEDYILRLWRKHS 52

Query: 174 NKLQILNSIFP 184
            KL ++N I+P
Sbjct: 51  AKLPLINYIWP 19

 Score = 85.9 bits (211), Expect(2) = 4e-77,   Method: Compositional matrix adjust.
 Identities = 38/58 (65%), Positives = 46/58 (79%), Gaps = 1/58 (1%)
 Frame = -2

Query: 1   MPDQALQQMLDR-SCWVCFATDEDDRTAEWVRPCRCRGSTKWVHQACLQRWVDEKQRG 57
           M    L++  +R SCWVCFAT+EDD  A WVRPCRCRG+TKWVHQ+CLQRWVDE ++ 
Sbjct: 572 MSQSRLREENERQSCWVCFATEEDDTEAVWVRPCRCRGTTKWVHQSCLQRWVDENRKA 399
>06740
          Length = 1867

 Score = 34.3 bits (77), Expect = 0.054,   Method: Compositional matrix adjust.
 Identities = 18/56 (32%), Positives = 27/56 (48%), Gaps = 1/56 (1%)
 Frame = -2

Query: 2    PDQALQQMLDRSCWVC-FATDEDDRTAEWVRPCRCRGSTKWVHQACLQRWVDEKQR 56
            PD   +  L   C +C    D++D       PCRC G+  +VH  CL +W++   R
Sbjct: 1410 PDSDTETDLLPVCRICQLPGDKEDF---LFSPCRCSGTMMFVHYLCLLKWIEISTR 1252
>14294
          Length = 584

 Score = 32.7 bits (73), Expect = 0.18,   Method: Compositional matrix adjust.
 Identities = 12/37 (32%), Positives = 19/37 (51%)
 Frame = +3

Query: 13  SCWVCFATDEDDRTAEWVRPCRCRGSTKWVHQACLQR 49
            CW+C+  +  D     ++PC C+G    VH  CL+ 
Sbjct: 78  DCWICYDPERKD-AGPLIQPCLCKGDMASVHHDCLKN 185
>00275
          Length = 1513

 Score = 28.9 bits (63), Expect = 2.7,   Method: Compositional matrix adjust.
 Identities = 16/50 (32%), Positives = 23/50 (46%), Gaps = 1/50 (2%)
 Frame = -2

Query: 38  STKWVHQACLQRWVDEKQRGNSTARVACPQC-NAEYLIVFPKLGPVVYAL 86
           +  W+   CLQ  VD+  R  S     CP+C +  Y    P L  V++ L
Sbjct: 987 TKAWIRAVCLQGLVDQGSRSESF----CPECVHRFYNCTLPLLSSVLFCL 850
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31543976|ref|NP_061359.2| 3-monooxgenase/tryptophan
5-monooxygenase activation protein, gamma polypeptide [Mus musculus]
         (247 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

12344                                                                 283   5e-77
13465                                                                 181   3e-46
33715                                                                 168   2e-42
17028                                                                 127   5e-30
15092                                                                 121   3e-28
27988                                                                  71   1e-20
>12344
          Length = 1658

 Score =  283 bits (723), Expect = 5e-77,   Method: Compositional matrix adjust.
 Identities = 146/235 (62%), Positives = 178/235 (75%)
 Frame = +2

Query: 1   MVDREQLVQKARLAEQAERYDDMAAAMKNVTELNEPLSNEERNLLSVAYKNVVGARRSSW 60
           M DRE  V +A+   +AERYD+M   MK V  ++  L+ EERNLLSVAYKNV+GARR+SW
Sbjct: 56  MGDREDQVYQAKQLNRAERYDEMVKFMKIVACMDVELTVEERNLLSVAYKNVIGARRASW 235

Query: 61  RVISSIEQKTSADGNEKKIEMVRAYREKIEKELEAVCQDVLSLLDNYLIKNCSETQYESK 120
           R++SS+EQK   D  E K  + + YR KIEKEL+ +C+DVL +L+ +LI N +    ESK
Sbjct: 236 RIVSSLEQKE--DKCEDKKAINKEYRMKIEKELKDICEDVLDILEKHLIVNANTG--ESK 403

Query: 121 VFYLKMKGDYYRYLAEVATGEKRATVVESSEKAYSEAHEISKEHMQPTHPIRLGLALNYS 180
           VFY KMKGDY+RYLAE A G  R    E+S  AY  A +I+   + PTHPIRLGLALN+S
Sbjct: 404 VFYYKMKGDYHRYLAEFAVGNDRKEAAENSLVAYKAASDIAMIELAPTHPIRLGLALNFS 583

Query: 181 VFYYEIQNAPEQACHLAKTAFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTS 235
           VFYYEI N+P++AC LAK AFDDAIAELDTL+E+SYKDSTLIMQLLRDNLTLWTS
Sbjct: 584 VFYYEILNSPDRACRLAKAAFDDAIAELDTLSEESYKDSTLIMQLLRDNLTLWTS 748
>13465
          Length = 596

 Score =  181 bits (459), Expect = 3e-46,   Method: Compositional matrix adjust.
 Identities = 90/154 (58%), Positives = 114/154 (74%)
 Frame = +2

Query: 1   MVDREQLVQKARLAEQAERYDDMAAAMKNVTELNEPLSNEERNLLSVAYKNVVGARRSSW 60
           M DR+  V +A+LAEQAERYD+M  AMK V  +   L+ EERNLLSVAYKNV+GARR+SW
Sbjct: 110 MTDRDDFVYQAKLAEQAERYDEMVEAMKKVASMGNDLTVEERNLLSVAYKNVIGARRASW 289

Query: 61  RVISSIEQKTSADGNEKKIEMVRAYREKIEKELEAVCQDVLSLLDNYLIKNCSETQYESK 120
           R++SS+EQK     +  K +M + YR++IE EL+ +C+DVL ++D++LI   S TQ ESK
Sbjct: 290 RIVSSVEQKDLDKPDPDKGKMTKGYRQQIETELKQICEDVLKIIDDHLIP--STTQGESK 463

Query: 121 VFYLKMKGDYYRYLAEVATGEKRATVVESSEKAY 154
           VFY KMKGDYYRYLAE ATG+ R    ESS  AY
Sbjct: 464 VFYYKMKGDYYRYLAEFATGDPRKEAAESSLVAY 565
>33715
          Length = 434

 Score =  168 bits (425), Expect = 2e-42,   Method: Compositional matrix adjust.
 Identities = 79/112 (70%), Positives = 94/112 (83%)
 Frame = -1

Query: 124 LKMKGDYYRYLAEVATGEKRATVVESSEKAYSEAHEISKEHMQPTHPIRLGLALNYSVFY 183
           LKMKGDYYRYL+EV+ GE+R   V  S +AY EA +++KE +  THPIRLGLALN+SVF+
Sbjct: 374 LKMKGDYYRYLSEVSQGEQRKENVGKSMEAYKEATDMAKERLSSTHPIRLGLALNFSVFH 195

Query: 184 YEIQNAPEQACHLAKTAFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTS 235
           YEI+N P++AC LAK AFD+AI  LD LNE+SYKDSTLIMQLLRDNLTLWTS
Sbjct: 194 YEIKNCPDEACRLAKIAFDEAIQCLDQLNEESYKDSTLIMQLLRDNLTLWTS 39
>17028
          Length = 1078

 Score =  127 bits (318), Expect = 5e-30,   Method: Compositional matrix adjust.
 Identities = 61/90 (67%), Positives = 74/90 (82%), Gaps = 1/90 (1%)
 Frame = +1

Query: 147 VESSEKAYSEAHEISKEHMQPTHPIRLGLALNYSVFYYEIQNAPEQACHLAKTAFDDAIA 206
           V  +++AY++A E++K+ M PTHP RLGLALNYSVFYYEI N+ ++AC LAKTAFD+AI 
Sbjct: 37  VTKAQEAYNKAMEVAKQSMAPTHPNRLGLALNYSVFYYEILNSQDKACDLAKTAFDEAIQ 216

Query: 207 ELDTLNE-DSYKDSTLIMQLLRDNLTLWTS 235
           E+D   E D  KDSTLIMQLLRDNLTLWTS
Sbjct: 217 EMDQCGERDDCKDSTLIMQLLRDNLTLWTS 306
>15092
          Length = 692

 Score =  121 bits (303), Expect = 3e-28,   Method: Compositional matrix adjust.
 Identities = 67/112 (59%), Positives = 83/112 (74%), Gaps = 8/112 (7%)
 Frame = +3

Query: 4   REQLVQKARLAEQAERYDDMAAAM-KNVTE-------LNEPLSNEERNLLSVAYKNVVGA 55
           +E+ V  A++AEQAERYDDMA +M K V E        +  L NEERNLLSVAYKNVVGA
Sbjct: 231 KERQVHAAKIAEQAERYDDMAESMHKCVVEGYSANGDKSSTLDNEERNLLSVAYKNVVGA 410

Query: 56  RRSSWRVISSIEQKTSADGNEKKIEMVRAYREKIEKELEAVCQDVLSLLDNY 107
           RRS+WRVISSIEQKT  + N+KK+EM + YREK+EKEL+ +C  VL  + +Y
Sbjct: 411 RRSAWRVISSIEQKT--ENNDKKLEMAKKYREKVEKELKEICTQVLVRIHHY 560
>27988
          Length = 448

 Score = 70.9 bits (172), Expect(2) = 1e-20,   Method: Compositional matrix adjust.
 Identities = 38/60 (63%), Positives = 45/60 (75%)
 Frame = +3

Query: 44  LLSVAYKNVVGARRSSWRVISSIEQKTSADGNEKKIEMVRAYREKIEKELEAVCQDVLSL 103
           L SVAYKNVVGARRSSWRVI  IEQK  A+   +K E  RA+R+ +EKEL+A C +VL L
Sbjct: 276 LFSVAYKNVVGARRSSWRVICMIEQK--AETQPRK-EKARAFRKDVEKELDATCNEVLKL 446

 Score = 46.2 bits (108), Expect(2) = 1e-20,   Method: Compositional matrix adjust.
 Identities = 23/42 (54%), Positives = 30/42 (71%)
 Frame = +2

Query: 1   MVDREQLVQKARLAEQAERYDDMAAAMKNVTELNEPLSNEER 42
           + + + L+  A+LAEQAERYDDMA AMK VTE ++ L  E R
Sbjct: 146 LTESKDLISFAKLAEQAERYDDMAKAMKKVTENDKTLMQESR 271
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|70906453|ref|NP_080878.2| breast carcinoma amplified
sequence 2 [Mus musculus]
         (225 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

09375                                                                 282   9e-77
19361                                                                  30   0.90 
30835                                                                  27   6.4  
00739                                                                  27   6.6  
>09375
          Length = 1361

 Score =  282 bits (721), Expect = 9e-77,   Method: Compositional matrix adjust.
 Identities = 127/212 (59%), Positives = 168/212 (79%)
 Frame = -2

Query: 7   VAGEVVVDALPYFDQGYEAPGVRXXXXXXXXXXTRRYRPTKNYLSYLTAPDYSAFETDIM 66
           +AGEVVVDALPY+DQGY+ PGVR          TRRYRPTKNYL ++  P+Y AFET+I+
Sbjct: 955 MAGEVVVDALPYYDQGYDEPGVREAAIALVEEETRRYRPTKNYLDFIPTPNYHAFETEIL 776

Query: 67  RNEFERLAARQPIELLSMKRYELPAPSSGQKNDITAWQECVNNSMAQLEHQAVRIENLEL 126
           +NE ER+ AR P+++LSMKRYELP P +G+  DI AWQECV+NS AQLEHQA+RI NLE+
Sbjct: 775 KNEMERVQARLPMDMLSMKRYELPQPPAGKMTDIAAWQECVDNSQAQLEHQALRILNLEM 596

Query: 127 MSQHGCNAWKVYNENLVHMIEHAQKELQKLRKHIQDLNWQRKNMQLTAGSKLREMESNWV 186
           M+ +G  +WK YN+ LV MI+ AQK+LQ LRK IQ++NWQRKN Q  AG+KLRE+E++WV
Sbjct: 595 MADYGIPSWKTYNDTLVSMIDSAQKQLQDLRKKIQEINWQRKNEQTQAGTKLRELETSWV 416

Query: 187 SLVSKNYEIERTIVQLENEIYQIKQQHGEANK 218
            LVSKNYEIER  V+LE E+ ++++++ + ++
Sbjct: 415 GLVSKNYEIERACVELEKEVAEMEERNAKMDQ 320
>19361
          Length = 685

 Score = 30.0 bits (66), Expect = 0.90,   Method: Compositional matrix adjust.
 Identities = 25/106 (23%), Positives = 44/106 (41%)
 Frame = -1

Query: 40  TRRYRPTKNYLSYLTAPDYSAFETDIMRNEFERLAARQPIELLSMKRYELPAPSSGQKND 99
           T R RPT  Y     +PD +   +D +          +P + +   +YE P     Q  +
Sbjct: 469 TLRVRPTGTYRRQGVSPDITDDSSDNVDTVNSTPEEDEPEQSIDWTQYEKPHVFKVQNFN 290

Query: 100 ITAWQECVNNSMAQLEHQAVRIENLELMSQHGCNAWKVYNENLVHM 145
              W E   N M  L  Q V+ ++  + +   C+  ++ NE + +M
Sbjct: 289 GLNWCELCANFMWGLIAQGVKCQDCGVQTHKKCSE-RMPNECMPNM 155
>30835
          Length = 992

 Score = 26.9 bits (58), Expect = 6.4,   Method: Compositional matrix adjust.
 Identities = 18/58 (31%), Positives = 24/58 (41%), Gaps = 16/58 (27%)
 Frame = +2

Query: 78  PIELLSMKRYELP----APSSGQKNDITAWQECVNNS------------MAQLEHQAV 119
           P+   S++R   P     P   + N    W EC+N S            MA L+HQAV
Sbjct: 86  PVTRTSIQRQSFPVRRPTPVRERSNQEVHWNECLNPSLDRENPRRIWIKMATLKHQAV 259
>00739
          Length = 1313

 Score = 26.9 bits (58), Expect = 6.6,   Method: Compositional matrix adjust.
 Identities = 10/21 (47%), Positives = 15/21 (71%)
 Frame = -1

Query: 144 HMIEHAQKELQKLRKHIQDLN 164
           H ++H+ +ELQ L+ H QDL 
Sbjct: 515 HGVQHSARELQLLQHHAQDLG 453
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|188219757|ref|NP_613066.2| aldehyde dehydrogenase 7
family, member A1 isoform a [Mus musculus]
         (539 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

18652                                                                 283   1e-76
28082                                                                 187   1e-47
11245                                                                 132   4e-31
27685                                                                  99   5e-21
31624                                                                  92   6e-19
31982                                                                  59   7e-09
25921                                                                  56   3e-08
25364                                                                  31   1.1  
>18652
          Length = 759

 Score =  283 bits (723), Expect = 1e-76,   Method: Compositional matrix adjust.
 Identities = 130/189 (68%), Positives = 156/189 (82%)
 Frame = -1

Query: 351 RSAYSQIRVGNPWDPNILYGPLHTKQAVSMFVRAVEEAKKQGGTVVYGGKVMDHPGNYVE 410
           R   S  R  +P D  + YGPLH+ Q V++F +AV +A  QGG + YGGK ++ PGN+VE
Sbjct: 720 RRTLSSYR--DPLDEGVNYGPLHSPQGVALFQQAVADAVAQGGKIEYGGKPIERPGNFVE 547

Query: 411 PTIVTGLAHDAPIVHQETFAPILYVFKFQDEEEVFEWNNEVKQGLSSSIFTKDLGRIFRW 470
           PTI++GL+HDAP+VH+ETFAPI+Y  K  + +E   WNNEVKQGL+SS+FTKDL  +F+W
Sbjct: 546 PTIISGLSHDAPVVHRETFAPIVYALKTTNLDEAIAWNNEVKQGLTSSLFTKDLANVFKW 367

Query: 471 LGPKGSDCGIVNVNIPTSGAEIGGAFGGEKHTGGGRESGSDAWKQYMRRSTCTINYSTSL 530
           +GPKGSDCGIVNVNIPTSGAEIGGAFGGEKHTGGGRESGSDAWKQYMRRSTCTIN+S  L
Sbjct: 366 IGPKGSDCGIVNVNIPTSGAEIGGAFGGEKHTGGGRESGSDAWKQYMRRSTCTINFSKEL 187

Query: 531 PLAQGIKFQ 539
           PLAQGIKF+
Sbjct: 186 PLAQGIKFE 160
>28082
          Length = 445

 Score =  187 bits (475), Expect = 1e-47,   Method: Compositional matrix adjust.
 Identities = 93/149 (62%), Positives = 115/149 (77%)
 Frame = -1

Query: 110 RGEIVRKIGDAFREKIQLLGRLVSLEMGKILVEGIGEVQEYVDVCDYAAGLSRMIGGPTL 169
           RG+IVR+IGD  R+  + LG+LVSLE+GKI  EG GEVQE++D+CDYA GLSR+  G  +
Sbjct: 445 RGDIVRQIGDELRKYKEPLGKLVSLEVGKIYSEGQGEVQEFIDICDYAVGLSRIYAGQLI 266

Query: 170 PSERPGHALIEMWNPLGLVGIITAFNFPVAVFGWNNAIALITGNVCLWKGAPTTSLVSVA 229
            SER  H ++E W PLGLVG+I+A+NFP AVFGWN AIALITGN  LWKGAP+T LVSVA
Sbjct: 265 NSERVEHTILEAWRPLGLVGVISAYNFPNAVFGWNAAIALITGNSVLWKGAPSTPLVSVA 86

Query: 230 VTKIIAQVLEDNLLPGAICSLVCGGADIG 258
            T+I+A+VL  N LP A+  L  GG D+G
Sbjct: 85  TTRIVAEVLHRNNLP-AVVGLCQGGTDVG 2
>11245
          Length = 993

 Score =  132 bits (332), Expect = 4e-31,   Method: Compositional matrix adjust.
 Identities = 91/299 (30%), Positives = 147/299 (49%), Gaps = 17/299 (5%)
 Frame = +2

Query: 255 ADIGTTMARDERVNLLSFTGSTQVGKEVALMVQERFGKSLLELGGNNAIIAFEDADLSLV 314
           A IG    +   V  +SFTGSTQVGK +     +   +  LELGGN   I F+ A++   
Sbjct: 53  APIGELFCKSPDVRGISFTGSTQVGKLLFRNCADGIKRVCLELGGNAPFIVFDSANVEKA 232

Query: 315 VPSVLFAAVGTAGQRCTTVRRLFLHESIHNEVVDRLRSAYSQIRVGNPWDPNILYGPLHT 374
           V   + +     GQ C +  R F+ E ++++ V +L+     +++G+    ++  GPL  
Sbjct: 233 VDGAMASKFRNCGQTCVSANRFFVQEGVYDKFVSQLKQRVEALKIGDGKSSDVQIGPLIN 412

Query: 375 KQAVSMFVRAVEEAKKQGGTVVYGGKVMDHPGN-YVEPTIVTGLAHDAPIVHQETFAPIL 433
           K         VE+A+ +   V+ GGK +   G+ +  PTIVT +   A +  +E F P++
Sbjct: 413 KMQFDKVSGFVEDARSKKANVIVGGKALQEFGSLFYAPTIVTDVPPSAQLYTEEVFGPVV 592

Query: 434 YVFKFQDEEEVFEWNNEVKQGLSSSIFTKDLGRIFRWLGPKGSDCGIVNVNIPTSGAEIG 493
            + KF+DE E     N+ ++GL+   ++ +L ++FR    K  + G+V VN     A   
Sbjct: 593 SIIKFKDEAEAVXQANDTQRGLAGYFYSDNLQQVFRV--AKRLEVGMVGVNEGIISAP-E 763

Query: 494 GAFGGEKHTGGGRES---GSDAW---KQYMR-RSTCTIN---------YSTSLPLAQGI 536
             FGG K +G GRE    G D +   K YM  +S   +N          S+SLPL + +
Sbjct: 764 APFGGVKESGIGREGSHHGIDDYVDIKIYMHGQSQIRLNLLKMPLA*ALSSSLPLDKSL 940
>27685
          Length = 735

 Score = 98.6 bits (244), Expect = 5e-21,   Method: Compositional matrix adjust.
 Identities = 64/232 (27%), Positives = 112/232 (48%), Gaps = 4/232 (1%)
 Frame = +2

Query: 112 EIVRKIGDAFREKIQLLGRLVSLEMGKILVEGIGEVQEYVDVCDYAAGLSRMIGGPTLPS 171
           +++ +     +E+ + L R+  L+ GK + E   ++Q   D   Y  G+      PTL  
Sbjct: 2   QVLTRAAILIQEREEELARMEVLDTGKPIWEARYDIQGCADTIQYYGGIV-----PTLVG 166

Query: 172 ERP----GHALIEMWNPLGLVGIITAFNFPVAVFGWNNAIALITGNVCLWKGAPTTSLVS 227
           E      G     +  PLG+VG I A+N+P  +  W ++ AL  GN  ++K +P T L +
Sbjct: 167 EHTKLSGGSFAYTLREPLGVVGAIGAWNYPFQMAAWKSSPALACGNTMVFKPSPFTPLTA 346

Query: 228 VAVTKIIAQVLEDNLLPGAICSLVCGGADIGTTMARDERVNLLSFTGSTQVGKEVALMVQ 287
           V    ++ ++  +  LP    +++ G  + G  ++  + +  +SFTGS   G ++     
Sbjct: 347 V----MLGEIYREAGLPDGCYNVIQGEGETGQLISHHDDIAKMSFTGSVATGSKIMAACA 514

Query: 288 ERFGKSLLELGGNNAIIAFEDADLSLVVPSVLFAAVGTAGQRCTTVRRLFLH 339
           +      LELGG + +I FEDADL   V   + A   + GQ C+   R+F+ 
Sbjct: 515 QGIKHVTLELGGKSPLIIFEDADLDNAVKGAMLANFLSQGQVCSNGTRVFVQ 670
>31624
          Length = 2324

 Score = 91.7 bits (226), Expect = 6e-19,   Method: Compositional matrix adjust.
 Identities = 72/290 (24%), Positives = 131/290 (45%), Gaps = 7/290 (2%)
 Frame = +1

Query: 184 PLGLVGIITAFNFPVAVFGWNNAIALITGNVCLWKGAPTTSLVSVAVTKIIAQVLEDNLL 243
           PLG+V  IT FNFP  +  W   +A + GN C+ K     S      T I+ ++L++  +
Sbjct: 46  PLGVVAGITPFNFPAMIPLWMFPMAAVCGNTCILK----PSERDPGATMILMELLQEAGM 213

Query: 244 PGAICSLVCGGADIGTTMARDERVNLLSFTGSTQVGKEVALMVQERFGKSLLELGGNNAI 303
           P  I +++ G  D    +  +  +  +SF GS Q G+ +     +   +    +G  N  
Sbjct: 214 PPGIVNVIHGRHDSVNFICDNPDIKAISFVGSDQAGEYIYERGSKNGKRVQANMGAKNHG 393

Query: 304 IAFEDADLSLVVPSVLFAAVGTAGQRCTTVRR-LFLHESIH--NEVVDRLRSAYSQIRVG 360
           +   DA+    +  ++ AA G AGQRC  +   +F+ E+     E+V+R ++    ++V 
Sbjct: 394 VIMPDANKESTLTQLVGAAFGAAGQRCMALSTAVFVGEAKKWIPELVERAKA----LKVT 561

Query: 361 NPWDPNILYGPLHTKQAVSMFVRAVEEAKKQGGTVVYGGKVMDHP----GNYVEPTIVTG 416
              +     GPL + ++       V+     G  ++  G+ +  P    GN+V PTI+  
Sbjct: 562 GGTEKGADLGPLISPESKKRVCDLVQAGVDAGADLLLDGRGVQVPGYEKGNFVGPTILHQ 741

Query: 417 LAHDAPIVHQETFAPILYVFKFQDEEEVFEWNNEVKQGLSSSIFTKDLGR 466
           +  +     +E F P+L   +    +E  +  N    G  ++IFT + G 
Sbjct: 742 VDPNMKCYTEEIFGPVLVSMEVDTLDEAIDIVNANPYGNGTAIFTTNGGH 891
>31982
          Length = 555

 Score = 58.5 bits (140), Expect = 7e-09,   Method: Compositional matrix adjust.
 Identities = 33/82 (40%), Positives = 43/82 (52%), Gaps = 5/82 (6%)
 Frame = +2

Query: 390 KQGGTVVYGGKVMD-----HPGNYVEPTIVTGLAHDAPIVHQETFAPILYVFKFQDEEEV 444
           KQG  VV GG+ +        G Y+ P I+TG   D  +V +E F  +L V  F  +EEV
Sbjct: 2   KQGARVVCGGERVTPSAELSGGIYLSPCILTGCHDDMTVVQEEVFGSVLSVLTFDTQEEV 181

Query: 445 FEWNNEVKQGLSSSIFTKDLGR 466
               N+ + GL+  IFTKDL R
Sbjct: 182 VRRANBTELGLAGGIFTKDLKR 247
>25921
          Length = 425

 Score = 56.2 bits (134), Expect = 3e-08,   Method: Composition-based stats.
 Identities = 31/100 (31%), Positives = 51/100 (51%), Gaps = 5/100 (5%)
 Frame = +2

Query: 254 GADIGTTMARDERVNLLSFTGSTQVGKEVALMVQERFGKS-----LLELGGNNAIIAFED 308
           G   G  ++    +N ++FTGS  VG+    ++ E   KS      LELGG + ++ F+D
Sbjct: 26  GPTAGAAISEHPDINKVAFTGSVDVGR----IIMEAAAKSNLKRISLELGGKSPVVVFDD 193

Query: 309 ADLSLVVPSVLFAAVGTAGQRCTTVRRLFLHESIHNEVVD 348
           AD+   V +   A     GQ C    R ++HE I+++ V+
Sbjct: 194 ADIDFAVETXHEALFSNHGQSCCAGSRTYVHEKIYDKFVE 313
>25364
          Length = 619

 Score = 31.2 bits (69), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 15/33 (45%), Positives = 19/33 (57%)
 Frame = +1

Query: 496 FGGEKHTGGGRESGSDAWKQYMRRSTCTINYST 528
           FGG K +G GRE G  A K+Y    T TI  ++
Sbjct: 103 FGGFKQSGQGRELGEYALKEYTEIKTVTIKLAS 201
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|21703854|ref|NP_663403.1| dehydrogenase/reductase
(SDR family) member 7B [Mus musculus]
         (323 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

03060                                                                 282   1e-76
36378                                                                 117   5e-27
03983                                                                 100   7e-22
12867                                                                  95   4e-20
35613                                                                  88   5e-18
07400                                                                  74   7e-14
05690                                                                  68   4e-12
12758                                                                  67   9e-12
28229                                                                  44   2e-11
18534                                                                  66   2e-11
00991                                                                  61   7e-10
18041                                                                  60   1e-09
23588                                                                  57   1e-08
05194                                                                  52   2e-07
30783                                                                  39   1e-06
11922                                                                  44   7e-05
27168                                                                  44   1e-04
05235                                                                  43   2e-04
36857                                                                  34   0.096
12249                                                                  29   3.2  
>03060
          Length = 1893

 Score =  282 bits (722), Expect = 1e-76,   Method: Compositional matrix adjust.
 Identities = 149/290 (51%), Positives = 192/290 (66%), Gaps = 9/290 (3%)
 Frame = -1

Query: 30   GCLGIFSLFRLLQRIRSKAYLRN-------AVVVVTGATSGLGRECAKVFHAAGAKLVLC 82
            G  G+ +L  L  RIR+   LR         VV+VTGA+SGLG+ CAKVFH  G +++L 
Sbjct: 1776 GVGGVVALAFLWHRIRTFIKLRTRAADIQGKVVLVTGASSGLGKACAKVFHQHGCQVILA 1597

Query: 83   GRNVKALEELSRELAGSSQGQTH--QPFVVTFDLADPGTIAAAAAEILQCFGYVDVLINN 140
            GR+V+ L  +   L   S+G+    +P V+  DL D  ++   A   ++ FG VDV+INN
Sbjct: 1596 GRSVERLNAVKDYLT-KSEGEVKACEPSVLAMDLEDLNSLQQLAERAVELFGKVDVVINN 1420

Query: 141  AGISYRGTISDTIVDVDRKVMEINYFGPVALTKALLPSMVERKQGHIVAISSIQGKISIP 200
            AGISYRG I DT + VD+K+M +NYFG VAL K LLP M  R  GHIV ISS+QGKISIP
Sbjct: 1419 AGISYRGCIEDTSIQVDQKLMAVNYFGHVALIKGLLPHMQARNSGHIVGISSVQGKISIP 1240

Query: 201  FRSAYSASKHATQAFFDCLRAEMEEANIKVTVISPGYIHTNLSVNAVTADGSRYGALDKN 260
            +RSAYSASKHA QAFFDCLRAE+    IKV+++SPGYI TNLS NAV  DG+ YG +DK 
Sbjct: 1239 YRSAYSASKHALQAFFDCLRAELSCTKIKVSLLSPGYIKTNLSNNAVCGDGTTYGVMDKT 1060

Query: 261  TAQGRSAAEVAQDVFDAVGKKKKDVLLTDFVPSMAVYIRTLAPGLFFRIM 310
            T  G +   VAQ V  A+ K++ DV++   V   A+ +R +AP +FF IM
Sbjct: 1059 TEAGMTPEAVAQTVLHAILKQEPDVVVAPCVHKXAIVLRAVAPAVFFAIM 910
>36378
          Length = 552

 Score =  117 bits (294), Expect = 5e-27,   Method: Compositional matrix adjust.
 Identities = 58/142 (40%), Positives = 84/142 (59%)
 Frame = -3

Query: 81  LCGRNVKALEELSRELAGSSQGQTHQPFVVTFDLADPGTIAAAAAEILQCFGYVDVLINN 140
           L  R  + LE + ++   S   +    FVVT D     T   A   +LQ FG +D+L+NN
Sbjct: 523 LSARRTQELERVKKQCLLSGPLKEEDVFVVTLDCLQYDTHIPAVQTVLQHFGQIDILVNN 344

Query: 141 AGISYRGTISDTIVDVDRKVMEINYFGPVALTKALLPSMVERKQGHIVAISSIQGKISIP 200
           AG S R     T +DVDR+++E+N  G ++LTKA+LP M++R +GH+V +SSI GK   P
Sbjct: 343 AGRSQRAEWVKTSLDVDRQMLELNVLGVLSLTKAVLPHMMQRGRGHMVVMSSIAGKCGAP 164

Query: 201 FRSAYSASKHATQAFFDCLRAE 222
              +Y+ SKHA   +F+ LR E
Sbjct: 163 MSGSYTGSKHALHGWFESLRVE 98
>03983
          Length = 1099

 Score =  100 bits (249), Expect = 7e-22,   Method: Compositional matrix adjust.
 Identities = 69/210 (32%), Positives = 107/210 (50%), Gaps = 7/210 (3%)
 Frame = +2

Query: 40  LLQRIRSKAYLRNAV----VVVTGATSGLGRECAKVFHAAGAKLVLCGRNVKALEELSRE 95
           +++ I    + R +V    V++TGA SGLG+  A  F   G  LVL   N +A+E + R+
Sbjct: 128 IVKCILPSKFFRKSVEGQRVLITGAGSGLGKLMAYRFMGLGCDLVLWDINTEAIEAMERD 307

Query: 96  LAGSSQGQTHQPFVVTFDLADPGTIAAAAAEILQCFGYVDVLINNAGISYRGTISDTIVD 155
           +     GQ       T DL+    I  AA ++ +  G VD+L+NNAGI       D    
Sbjct: 308 M-----GQQVSCKAYTVDLSSREQIYKAADQVKREVGGVDILVNNAGIVTGRKFLDCPDS 472

Query: 156 VDRKVMEINYFGPVALTKALLPSMVERKQGHIVAISSIQGKISIPFRSAYSASKHATQAF 215
           +  K ME+N        KA LP+M+ + +GHI++I+S  G   +   + Y ASK A   F
Sbjct: 473 LIEKTMEVNSNAHFWTVKAFLPNMLAQNKGHIISIASSAGLFGVTGLADYCASKFAAVGF 652

Query: 216 FDCLRAEME---EANIKVTVISPGYIHTNL 242
            + LR E+E   +  +  TV+ P +I+T +
Sbjct: 653 DESLRFELEAMGKTGVHTTVVCPYFINTGM 742
>12867
          Length = 858

 Score = 94.7 bits (234), Expect = 4e-20,   Method: Compositional matrix adjust.
 Identities = 67/213 (31%), Positives = 105/213 (49%), Gaps = 5/213 (2%)
 Frame = -3

Query: 89  LEELSRELAGSSQGQTHQP--FVVTFDLADPGTIAAAAAEILQCFGYVDVLINNAGISYR 146
           LEE+  E   +++G   Q    V+  D+       +    +L  F  +DVL+NNAG S R
Sbjct: 853 LEEVQAECVTAARGLLAQNDVLVLPMDMLQLEEHQSHLYTVLNHFDRLDVLVNNAGRSQR 674

Query: 147 GTISDTIVDVDRKVMEINYFGPVALTKALLPSMVERK--QGHIVAISSIQGKISIPFRSA 204
              ++  + VDR + E++ F  V L++ ++   +E+   +GHI A SSI G   +PF + 
Sbjct: 673 ANWTEIEIQVDRDLFELDVFAVVNLSRLVVRYYLEQNGGRGHIAATSSIAGFSPVPFSAT 494

Query: 205 YSASKHATQAFFDCLRAEMEEANIKVTVISPGYIHTNLSVNAVT-ADGSRYGALDKNTAQ 263
           Y A+KHA  A+   L+  ME   + VT+ +PG   T+  + A T ADG + G    N  Q
Sbjct: 493 YCAAKHALNAYLMSLK--MEHRKLDVTIFAPGPTATDFLLEAFTGADGGKVGGSTAN--Q 326

Query: 264 GRSAAEVAQDVFDAVGKKKKDVLLTDFVPSMAV 296
            R  AE   ++F      K D+      P  A+
Sbjct: 325 KRLTAERCGELFAVALANKMDLTWCGLFPVNAL 227
>35613
          Length = 977

 Score = 87.8 bits (216), Expect = 5e-18,   Method: Compositional matrix adjust.
 Identities = 60/211 (28%), Positives = 105/211 (49%), Gaps = 11/211 (5%)
 Frame = +1

Query: 37  LFRLLQRIRSKA----YLRNAVVVVTGATSGLGRECAKVFHAAGAKLVLC-----GRNVK 87
           L+ L +R R  A     LR+  V++TG  +G G   AK  H  G  ++       G   K
Sbjct: 28  LYPLYRRHRRAAAGSVCLRDKTVLITGCDTGFGHALAKSLHEDGCHVIATVYQPDGDGAK 207

Query: 88  ALEELSRELAGSSQGQTHQPFVVTFDLADPGTIAAAAAEILQCFGYVDV--LINNAGISY 145
            L ++S          T +  V+  D++   ++      + Q   +  +  L+NNAG ++
Sbjct: 208 RLRDVS----------TDRMTVIPLDVSSDDSVEKCLRHVKQLCEHSGLWGLVNNAGHNF 357

Query: 146 RGTISDTIVDVDRKVMEINYFGPVALTKALLPSMVERKQGHIVAISSIQGKISIPFRSAY 205
            G +  T +     V  IN FG V  T+A LP ++    G IV ++SI+G++S P  +AY
Sbjct: 358 VGEVELTTMRQYLMVANINIFGMVRTTRAFLP-LLRHATGRIVNVTSIKGQLSTPMNAAY 534

Query: 206 SASKHATQAFFDCLRAEMEEANIKVTVISPG 236
           + +K+A + F +  + EM++  +KV+++ PG
Sbjct: 535 NITKYAGETFSEITQMEMKQFGVKVSIVEPG 627
>07400
          Length = 1577

 Score = 73.9 bits (180), Expect = 7e-14,   Method: Compositional matrix adjust.
 Identities = 54/191 (28%), Positives = 100/191 (52%), Gaps = 4/191 (2%)
 Frame = -3

Query: 51   RNAVVVVTGATSGLGRECAKVFHAAGAKLVLCGRNVKALEELSRELAGSSQ-GQTHQPFV 109
            ++ VV++TG  +G+G E A   +  G  +V    +V +        +G+ +  +     V
Sbjct: 1443 KDKVVLITGCDTGIGHEAALEANKRGLTVVAGCLDVTS--------SGAQRLAEKKGVHV 1288

Query: 110  VTFDLADPGTIAAA---AAEILQCFGYVDVLINNAGISYRGTISDTIVDVDRKVMEINYF 166
            +  D++   ++A A    +++ +  G   V INNAG +    +  T +     V ++  F
Sbjct: 1287 IRLDVSSDESVANAMKSVSKLCEAKGLWAV-INNAGFNRMSPVELTSMTTFHHVADVMLF 1111

Query: 167  GPVALTKALLPSMVERKQGHIVAISSIQGKISIPFRSAYSASKHATQAFFDCLRAEMEEA 226
            G V +TKA+LP +V R +G +V +SS +G  +  + SAY  +K   +AF D  R EM++ 
Sbjct: 1110 GTVRVTKAVLP-LVRRAKGRVVTVSSDRGMTTPAYSSAYCIAKFGVEAFSDVXRMEMKKY 934

Query: 227  NIKVTVISPGY 237
            ++ V++I PG+
Sbjct: 933  DVSVSIIQPGH 901
>05690
          Length = 1192

 Score = 68.2 bits (165), Expect = 4e-12,   Method: Compositional matrix adjust.
 Identities = 47/157 (29%), Positives = 76/157 (48%), Gaps = 3/157 (1%)
 Frame = +2

Query: 137 LINNAGISYRGTISDT-IVDVDRKVMEINYFGPVALTKALLPSMVERKQGHIVAISSIQG 195
           ++NNAGI + G +      DVD K++++NY G V + +A LP  + R +G +V ++S  G
Sbjct: 419 VVNNAGIMHIGCLEVMGQADVD-KILDVNYRGQVNVIRAFLP-FLRRSRGRLVNVASNTG 592

Query: 196 KISIPFRSAYSASKHATQAFFDCLRAEMEEANIKVTVISPGYIHTNLSVNAVTADGSRYG 255
              +P+ + Y ASK A  A  + LR E++   ++V+ I P    T +  +     G ++ 
Sbjct: 593 IAPVPYHAVYCASKAAVAALTESLRLELQPFGVRVSTIIPSGYRTGIQQHNTQTTGDKWW 772

Query: 256 ALDKNTAQGRSAAEVAQDVFDAVGKKK--KDVLLTDF 290
           A  K   +         D F    K K  K  L  DF
Sbjct: 773 AQAKQEVRD----SYGHDSFTPQNKTKDYKSYLNADF 871
>12758
          Length = 804

 Score = 67.0 bits (162), Expect = 9e-12,   Method: Compositional matrix adjust.
 Identities = 41/139 (29%), Positives = 67/139 (48%)
 Frame = -1

Query: 105 HQPFVVTFDLADPGTIAAAAAEILQCFGYVDVLINNAGISYRGTISDTIVDVDRKVMEIN 164
            +P ++  DL           E ++ FG +++L+N AGI   G I +T +D   ++   N
Sbjct: 741 QKPLLLVGDLTKEDDTKRVVEETVKQFGRLNILVNCAGIIELGNIENTSLDQYDRMFNTN 562

Query: 165 YFGPVALTKALLPSMVERKQGHIVAISSIQGKISIPFRSAYSASKHATQAFFDCLRAEME 224
                 LT   +P +V   QG+IV +SS+ G  S P   AY  +K A   F  C+  E+ 
Sbjct: 561 VRSVYHLTMLAVPHLV-NTQGNIVNVSSVNGMRSFPNVLAYCMAKSAIDQFTRCVALELA 385

Query: 225 EANIKVTVISPGYIHTNLS 243
              ++V  ++PG I + L 
Sbjct: 384 PKKVRVNGVNPGVIISELQ 328
>28229
          Length = 633

 Score = 44.3 bits (103), Expect(2) = 2e-11,   Method: Compositional matrix adjust.
 Identities = 34/92 (36%), Positives = 45/92 (48%)
 Frame = -2

Query: 60  ATSGLGRECAKVFHAAGAKLVLCGRNVKALEELSRELAGSSQGQTHQPFVVTFDLADPGT 119
           A+SG+G   A+V    GA L L GRNV  LE     L   + G   Q   V  D+     
Sbjct: 632 ASSGIGVAIAQVLAREGAVLSLVGRNVTNLEATRTTLQQQTTGV--QVLNVVADVTTDS- 462

Query: 120 IAAAAAEILQCFGYVDVLINNAGISYRGTISD 151
            AA   + +  +G +DVL+NNAGI   G + D
Sbjct: 461 -AAIIQQTINHYGRIDVLVNNAGILGNGPLID 369

 Score = 42.0 bits (97), Expect(2) = 2e-11,   Method: Compositional matrix adjust.
 Identities = 28/90 (31%), Positives = 45/90 (50%)
 Frame = -1

Query: 170 ALTKALLPSMVERKQGHIVAISSIQGKISIPFRSAYSASKHATQAFFDCLRAEMEEANIK 229
           A TKA LP +++ K G +V +SS  G    P   +Y  SK A   F   +  E+    ++
Sbjct: 315 AATKAALPHLLKTK-GAVVNVSSCAGICHFPGALSYGISKAALDQFTKIVSLELAPQGVR 139

Query: 230 VTVISPGYIHTNLSVNAVTADGSRYGALDK 259
           V  ++PG++ TN+         SR G +D+
Sbjct: 138 VNSVNPGFVVTNIH--------SRIGIVDE 73
>18534
          Length = 406

 Score = 65.9 bits (159), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 41/128 (32%), Positives = 64/128 (50%), Gaps = 3/128 (2%)
 Frame = -2

Query: 113 DLADPGTIAAAAAEILQCFGYVDVLINNAGISYRGTISDTIVDVDRKVMEINYFGPVALT 172
           D++D   I   AA+++   G+VDVLINNAGI       +    V +    IN        
Sbjct: 384 DISDREQIYQRAAQVIDDVGHVDVLINNAGIVCCKPFWELHDRVIQNTYNINIISHYWTV 205

Query: 173 KALLPSMVERKQGHIVAISSIQGKISIPFRSAYSASKHATQAFFDCLRAEMEEA---NIK 229
           KA LP M+   +GHIV + S+ G +     S Y+A+K+A   F + L  +++      I 
Sbjct: 204 KAFLPHMMRHNRGHIVTVGSVTGMLGTYGCSDYAATKYACIGFHESLLTDLKAHGYDQIH 25

Query: 230 VTVISPGY 237
           +++I P Y
Sbjct: 24  MSLICPYY 1
>00991
          Length = 1146

 Score = 60.8 bits (146), Expect = 7e-10,   Method: Compositional matrix adjust.
 Identities = 44/154 (28%), Positives = 77/154 (50%), Gaps = 6/154 (3%)
 Frame = +2

Query: 131 FGYVDVLINNAGISYRGTISDTIVDVDRKVMEINYFGPVALTKALLPSMVERK--QGHIV 188
            G VDV INNAG+++   +        + + ++N  G + +TK     M E     GHIV
Sbjct: 539 LGRVDVCINNAGLAHDAPLLTGDPAQWKHMFDVNVLGLMMVTKEAFTLMQENNIDDGHIV 718

Query: 189 AISSIQGK--ISIPFRSAYSASKHATQAFFDCLRAEMEE--ANIKVTVISPGYIHTNLSV 244
            ++S+ GK  ++      Y+ASK A  A F+ LR E+ E  + I+++ + PG + T  + 
Sbjct: 719 LVNSMSGKRVLNQKRTHCYAASKFAVTAIFEGLRNELRELKSKIRISQVCPGLVETQFAP 898

Query: 245 NAVTADGSRYGALDKNTAQGRSAAEVAQDVFDAV 278
             +  +G+      K T  G    + A+D+ D++
Sbjct: 899 RLMGEEGA------KATYSGYKCLQ-AEDIRDSI 979
>18041
          Length = 547

 Score = 59.7 bits (143), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 45/187 (24%), Positives = 81/187 (43%), Gaps = 5/187 (2%)
 Frame = -2

Query: 59  GATSGLGRECAKVFHAAGAKLVLCGRNVKALEELSRELAGSSQGQTHQPFVVTFDLADPG 118
           G+T G+G+  A      G  +VL  RN + L  +++E+    +       V+T D  +  
Sbjct: 546 GSTDGIGKCFALQLAEKGLDIVLISRNPEKLSAVAKEIVDQHKVSVK---VITADFKNAD 376

Query: 119 TIAAAAAEILQCFGYVDVLINNAGISYRGTI-----SDTIVDVDRKVMEINYFGPVALTK 173
                  ++      + +L+NN G+  R        +D      + ++ +N    V +T 
Sbjct: 375 IYDNIKRQLTGL--DIGILVNNVGMLNRRNPGYFCEADDFEQFHQDIINVNILACVQMTG 202

Query: 174 ALLPSMVERKQGHIVAISSIQGKISIPFRSAYSASKHATQAFFDCLRAEMEEANIKVTVI 233
            +LP M+ERK+G I+ I+S      +PF S YS +K     F   L  E     + + ++
Sbjct: 201 IVLPEMLERKRGLIINIASGAAIRPLPFFSVYSGTKAFISHFTQALNMEYSSQGVTIQLL 22

Query: 234 SPGYIHT 240
            P  + T
Sbjct: 21  IPNLVAT 1
>23588
          Length = 611

 Score = 57.0 bits (136), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 46/148 (31%), Positives = 68/148 (45%)
 Frame = +3

Query: 76  GAKLVLCGRNVKALEELSRELAGSSQGQTHQPFVVTFDLADPGTIAAAAAEILQCFGYVD 135
           GA+L L GR+   LE + ++   +    T     V  DL D        A  +  FG +D
Sbjct: 39  GARLSLTGRDATKLENVVQKCVAAGVKPTDV-VTVAGDLTDETFRQQLVASTVDKFGQID 215

Query: 136 VLINNAGISYRGTISDTIVDVDRKVMEINYFGPVALTKALLPSMVERKQGHIVAISSIQG 195
           VL+NNAG +  G +SB  ++    V  +N    VA++K  +P +++ K G+IV ISS   
Sbjct: 216 VLVNNAGFANPGLLSBPGMENLLNVFSLNLNAHVAMSKLCVPHLLQSK-GNIVNISSNLS 392

Query: 196 KISIPFRSAYSASKHATQAFFDCLRAEM 223
               P   AY  SK     F   L  E+
Sbjct: 393 MRPSPALGAYCMSKRHWTCFTRVLAYEL 476
>05194
          Length = 1075

 Score = 52.4 bits (124), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 25/64 (39%), Positives = 38/64 (59%)
 Frame = +1

Query: 179 MVERKQGHIVAISSIQGKISIPFRSAYSASKHATQAFFDCLRAEMEEANIKVTVISPGYI 238
           MV+R+ GHI+ ISS  G+   P  + YS SK   +     +R+E+ ++ +KVT I PG +
Sbjct: 22  MVKRESGHIINISSDAGRKGFPGLAVYSGSKFFVEGLSQAMRSEVADSGVKVTCIQPGDV 201

Query: 239 HTNL 242
            T L
Sbjct: 202 KTPL 213
>30783
          Length = 765

 Score = 38.5 bits (88), Expect(2) = 1e-06,   Method: Compositional matrix adjust.
 Identities = 19/56 (33%), Positives = 33/56 (58%)
 Frame = +2

Query: 128 LQCFGYVDVLINNAGISYRGTISDTIVDVDRKVMEINYFGPVALTKALLPSMVERK 183
           +  FG +D+L+NNAG++      DT  +   ++M+IN      L+K L P +++RK
Sbjct: 14  ISTFGRLDILVNNAGVARFVKPCDTTEEQYDEIMDINMKSVFFLSKLLAPELIKRK 181

 Score = 31.2 bits (69), Expect(2) = 1e-06,   Method: Compositional matrix adjust.
 Identities = 17/55 (30%), Positives = 26/55 (47%)
 Frame = +1

Query: 184 QGHIVAISSIQGKISIPFRSAYSASKHATQAFFDCLRAEMEEANIKVTVISPGYI 238
           +G IV +SSI     +     Y  SK A   F  CL  E+    ++V  ++PG +
Sbjct: 178 KGCIVNVSSICASRPMAEVGVYCMSKAAMDMFTQCLALELAPHGVRVNSVNPGSV 342
>11922
          Length = 2153

 Score = 44.3 bits (103), Expect = 7e-05,   Method: Compositional matrix adjust.
 Identities = 48/194 (24%), Positives = 83/194 (42%), Gaps = 8/194 (4%)
 Frame = +1

Query: 50  LRNAVVVVTGATSGLGRECAKVFHAAGAKLVLCGRNVKALEELSRELAGSSQ-----GQT 104
           L    V +TGA+ G+G+  A      GA +V+  +  +A  +L   +  +++     G  
Sbjct: 94  LVGKTVFITGASRGIGKAIAVKLAKDGANIVIAAKTAEAHPKLPGTIYTAAKEVEEAGGK 273

Query: 105 HQPFVVTFDLADPGTIAAAAAEILQCFGYVDVLINNA-GISYRGTISDTIVDVDRKVMEI 163
             P +V     D   +A  AA     FG +D+L+NNA  IS  GT+   +   D  +  I
Sbjct: 274 ALPCIVDIRNEDQVKVAVKAAA--DKFGGIDILVNNASAISLTGTLQTPMKRYDL-MNGI 444

Query: 164 NYFGPVALTKALLPSMVERKQGHIVAISSIQGKISIPFRS--AYSASKHATQAFFDCLRA 221
           N  G    ++  LP ++     HI+ IS      +  F+   AY+ +K+        +  
Sbjct: 445 NARGTYLCSQVCLPYLLRGSNPHILNISPPLNMSAKWFQGHVAYTMAKYGMSMCALGMAE 624

Query: 222 EMEEANIKVTVISP 235
           E  +  + V  + P
Sbjct: 625 EFRDDGVAVNALWP 666
>27168
          Length = 665

 Score = 43.5 bits (101), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 26/94 (27%), Positives = 43/94 (45%)
 Frame = +3

Query: 50  LRNAVVVVTGATSGLGRECAKVFHAAGAKLVLCGRNVKALEELSRELAGSSQGQTHQPFV 109
           L   V ++TGA  G+G E A+     G +++L  RN+   +E    +A        +   
Sbjct: 180 LHGRVALITGANCGIGFETARSLALHGCEIILACRNLATAQEAIDRIAVERPAARARCRT 359

Query: 110 VTFDLADPGTIAAAAAEILQCFGYVDVLINNAGI 143
            + DL     +     +I Q  G++D LI NAG+
Sbjct: 360 ASLDLGSLSDVKKFVEQIRQSVGHIDYLILNAGV 461
>05235
          Length = 944

 Score = 42.7 bits (99), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 59/212 (27%), Positives = 88/212 (41%), Gaps = 6/212 (2%)
 Frame = -2

Query: 37  LFRLLQRIRSKAYLRNAVVVVTGATSGLGRECAKVFHAAGAK-LVLCGR--NVKALEELS 93
           L +++ R  S       ++ V G   G+G +       +G K LV+  R  N  A+ EL 
Sbjct: 913 LTKIVNRXESMFIAGKNIIFVAG-LGGIGLDTNHEIVKSGPKNLVILDRIENPAAIAEL- 740

Query: 94  RELAGSSQGQTHQPFVVTFDLADPGTIAAAAAEILQCFGYVDVLINNAGISYRGTISDTI 153
            +        ++ P+ VT  +A+   +      +      VD+LIN AGI     I  TI
Sbjct: 739 -KAINPKVTISYYPYDVTVSVAESVKLLKT---VFAQLKKVDLLINGAGILDDHQIERTI 572

Query: 154 VDVDRKVMEINYFGPVALTKALLPSMVERKQGH---IVAISSIQGKISIPFRSAYSASKH 210
                    +N+ G V  T A++    +RK G    I  I S+ G  SI     YSASK 
Sbjct: 571 A--------VNFTGTVNTTTAIMEFWDKRKGGPGGVIANICSVTGFNSIYQVPVYSASKA 416

Query: 211 ATQAFFDCLRAEMEEANIKVTVISPGYIHTNL 242
              +F + L        + V  I+PG  HT L
Sbjct: 415 XALSFTNSLAKLAHITGVTVYSINPGITHTPL 320
>36857
          Length = 697

 Score = 33.9 bits (76), Expect = 0.096,   Method: Compositional matrix adjust.
 Identities = 24/85 (28%), Positives = 39/85 (45%), Gaps = 9/85 (10%)
 Frame = +2

Query: 131 FGYVDVLINNAGISYRGTISDTIVDVDRKVMEINYFGPVALTKALLPSMVERKQG----- 185
           FG +D+++NNAGI   G   DT      K ++IN  GP+  T+  L  +   K G     
Sbjct: 107 FGRLDIVVNNAGIG--GERDDTW----EKCVDINLKGPIRGTRLGLKYLRRDKGGEGGVD 268

Query: 186 --HIVA--ISSIQGKISIPFRSAYS 206
             HI+    +S  G+  + +   + 
Sbjct: 269 HQHIICRRFASAAGRAGVLWHKGWG 343
>12249
          Length = 403

 Score = 28.9 bits (63), Expect = 3.2,   Method: Compositional matrix adjust.
 Identities = 17/41 (41%), Positives = 22/41 (53%), Gaps = 2/41 (4%)
 Frame = -1

Query: 185 GHIV--AISSIQGKISIPFRSAYSASKHATQAFFDCLRAEM 223
           GH+V  A++ + G  SIP R      K AT AF +CL   M
Sbjct: 385 GHLVYEALNKVSGVGSIPTRVIPKMYK*ATLAFINCLTYRM 263
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|76559944|ref|NP_081170.1| MMP37-like protein,
mitochondrial [Mus musculus]
         (337 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

29124                                                                 282   1e-76
04112                                                                  30   1.4  
27842                                                                  29   2.9  
>29124
          Length = 1154

 Score =  282 bits (722), Expect = 1e-76,   Method: Compositional matrix adjust.
 Identities = 150/293 (51%), Positives = 196/293 (66%)
 Frame = +2

Query: 29  AYGSAVYRQAGPSAHQENPMLDLVFTVDDPVAWHAMNLKKNWSHYSFLKLLGPRIISSIQ 88
           AYGS V++Q G  A+  + MLD +  VD+P+ WH+ NLK+N  HYSFLK  G R ++ +Q
Sbjct: 2   AYGSGVFQQQG-HANMSSNMLDFILVVDNPLKWHSENLKRNRHHYSFLKYFGSRAVTMVQ 178

Query: 89  NNYGAGVYFNPLIRCDGKLIKYGVISTGTLIEDLLNWNNLYIAGRLQKPVKIVSMNENMA 148
             YGAGVYFN L+R + +LIKYGVIST  LI DLL+W+ LYI+GRL KPVK++ +  N  
Sbjct: 179 E-YGAGVYFNTLVRFEDRLIKYGVISTERLISDLLDWDTLYISGRLHKPVKLLVLPRNQD 355

Query: 149 LRAALDKNLRSAVTTACLMLPESFSEEDLFIEIAGLSYSGDFRMVIGEEKSKVLNIVKPN 208
           L +AL  NL+SAV TA L+LPE F EE L+  IAGLSY+GDFRMV+GE+++KV NIV PN
Sbjct: 356 LISALQVNLKSAVHTALLLLPEDFCEEALYTTIAGLSYNGDFRMVVGEDRNKVANIVGPN 535

Query: 209 VGHFRELYESILQKDPQVVYKMHQGQLEIDKSPEGQFTQLMTLPRTLQQQINHIMDPPGR 268
           + HFR LYES LQ +  V +   QG+LE + +   Q+  L  LP+T+   +      PG 
Sbjct: 536 MRHFRRLYESFLQTEEHVHWHPQQGRLEQNPNHVTQYHHLQLLPKTVLLLLQENRTRPGS 715

Query: 269 NRDVEETLLQVAQDPDCGDVVRLAISSIVRPSSIRQSTKGLFTAGMKKSVIYS 321
           + D+EE L   A    C D V   IS IV  SSI QS K + TAG +KSV+Y+
Sbjct: 716 HPDLEEVLKIYANSSHCDDSVARCISHIVWRSSIGQSAKTILTAGARKSVVYT 874
>04112
          Length = 973

 Score = 30.0 bits (66), Expect = 1.4,   Method: Compositional matrix adjust.
 Identities = 12/26 (46%), Positives = 20/26 (76%)
 Frame = +2

Query: 299 PSSIRQSTKGLFTAGMKKSVIYSSRK 324
           P++++QS+ G+F   M KSVIY S++
Sbjct: 236 PNNVQQSSAGIFNMXMIKSVIYHSQE 313
>27842
          Length = 621

 Score = 28.9 bits (63), Expect = 2.9,   Method: Compositional matrix adjust.
 Identities = 11/32 (34%), Positives = 18/32 (56%)
 Frame = +3

Query: 14  RRILAHFPEDLSLAFAYGSAVYRQAGPSAHQE 45
           RR+  H    ++L FA+ + +YR   PSA  +
Sbjct: 228 RRLYLHLKRSMALMFAFLACMYRNMVPSARHQ 323
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|8394252|ref|NP_058602.1| Sec61 alpha subunit homolog
[Mus musculus]
         (476 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

11779                                                                 283   1e-76
29817                                                                 263   8e-71
05072                                                                 208   4e-54
26212                                                                 196   1e-50
03057                                                                  66   3e-11
27825                                                                  30   2.8  
>11779
          Length = 460

 Score =  283 bits (724), Expect = 1e-76,   Method: Compositional matrix adjust.
 Identities = 135/153 (88%), Positives = 145/153 (94%)
 Frame = -2

Query: 160 LIVLLLDELLQKGYGLGSGISLFIATNICETIVWKAFSPTTVNTGRGMEFEGAIIALFHL 219
           +IVLLLDELLQKGYGLGSGISLFIATNICETI+WKA SP TVNTGRG EFEGA+IALFHL
Sbjct: 459 IIVLLLDELLQKGYGLGSGISLFIATNICETIMWKALSPATVNTGRGTEFEGALIALFHL 280

Query: 220 LATRTDKVRALREAFYRQNLPNLMNLIATIFVFAVVIYFQGFRVDLPIKSARYRGQYNTY 279
           LATR DKVR LREAFYRQNLPNLMNL+AT+ VFA+VIYFQGFRVDLPIKSARYRGQ  +Y
Sbjct: 279 LATRQDKVRGLREAFYRQNLPNLMNLMATVLVFAIVIYFQGFRVDLPIKSARYRGQQTSY 100

Query: 280 PIKLFYTSNIPIILQSALVSNLYVISQMLSARF 312
           PIKLFYTSNIPIILQSALVSNLY+ISQML+A+F
Sbjct: 99  PIKLFYTSNIPIILQSALVSNLYIISQMLAAKF 1
>29817
          Length = 551

 Score =  263 bits (673), Expect = 8e-71,   Method: Compositional matrix adjust.
 Identities = 126/140 (90%), Positives = 132/140 (94%)
 Frame = +2

Query: 337 PVGGLCYYLSPPESFGSVLEDPVHAVVYIVFMLGSCAFFSKTWIEVSGSSAKDVAKQLKE 396
           PVGGLCYYLSPPE+ G VLEDP+HAV+YIVFMLGSCAFFSKTWI+VSGSSAKDVAKQLKE
Sbjct: 2   PVGGLCYYLSPPETLGHVLEDPIHAVLYIVFMLGSCAFFSKTWIDVSGSSAKDVAKQLKE 181

Query: 397 QQMVMRGHRETSMVHELNRYIPTAAAFGGLCIGALSVLADFLGAIGSGTGILLAVTIIYQ 456
           QQMVMRGHRE SM+ ELNRYIPTAAAFGGLCIGALSVLADFLGAIGSGTGILLAVTIIYQ
Sbjct: 182 QQMVMRGHREQSMIKELNRYIPTAAAFGGLCIGALSVLADFLGAIGSGTGILLAVTIIYQ 361

Query: 457 YFEIFVKEQSEVGSMGALLF 476
           YFE FVKEQSE+G M  LLF
Sbjct: 362 YFEYFVKEQSEMGGMSTLLF 421
>05072
          Length = 1404

 Score =  208 bits (529), Expect = 4e-54,   Method: Compositional matrix adjust.
 Identities = 104/119 (87%), Positives = 109/119 (91%), Gaps = 1/119 (0%)
 Frame = +3

Query: 359 VHAVVYIVFMLGSCAFFSKTWIEVSGSSAKDVAKQLKEQQMVMRG-HRETSMVHELNRYI 417
           +HAV+YIVFMLGSCAFFSKTWI+VSGSSAKDVAKQLKEQQMV  G  RE SM+ ELNRYI
Sbjct: 3   IHAVLYIVFMLGSCAFFSKTWIDVSGSSAKDVAKQLKEQQMVNEGVTREKSMIKELNRYI 182

Query: 418 PTAAAFGGLCIGALSVLADFLGAIGSGTGILLAVTIIYQYFEIFVKEQSEVGSMGALLF 476
           PTAAAFGGLCIGALSVLADFLGAIGSGTGILLAVTIIYQYFE FVKEQSE+G M  LLF
Sbjct: 183 PTAAAFGGLCIGALSVLADFLGAIGSGTGILLAVTIIYQYFEYFVKEQSEMGGMSTLLF 359
>26212
          Length = 415

 Score =  196 bits (499), Expect = 1e-50,   Method: Compositional matrix adjust.
 Identities = 92/104 (88%), Positives = 100/104 (96%)
 Frame = -1

Query: 3   IKFLEVIKPFCVILPEIQKPERKIQFKEKVLWTAITLFIFLVCCQIPLFGIMSSDSADPF 62
           +KFLE +KPFC +LPEI KP+RKIQF+EKVLWTAITLFIFL+CCQIPLFGI+SSDSADPF
Sbjct: 313 LKFLEFVKPFCSVLPEIAKPDRKIQFREKVLWTAITLFIFLICCQIPLFGIVSSDSADPF 134

Query: 63  YWMRVILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVGDTP 106
           YW+RVILASNRGTLMELGISPIVTS LIMQLLAGAKIIEVGDTP
Sbjct: 133 YWIRVILASNRGTLMELGISPIVTSSLIMQLLAGAKIIEVGDTP 2
>03057
          Length = 2342

 Score = 65.9 bits (159), Expect = 3e-11,   Method: Compositional matrix adjust.
 Identities = 33/38 (86%), Positives = 34/38 (89%)
 Frame = +1

Query: 439 GAIGSGTGILLAVTIIYQYFEIFVKEQSEVGSMGALLF 476
           GAIGSGTGILLAVTIIYQYFE FVKEQSE+G M  LLF
Sbjct: 142 GAIGSGTGILLAVTIIYQYFEYFVKEQSEMGGMSTLLF 255
>27825
          Length = 542

 Score = 29.6 bits (65), Expect = 2.8,   Method: Compositional matrix adjust.
 Identities = 15/33 (45%), Positives = 17/33 (51%), Gaps = 1/33 (3%)
 Frame = -1

Query: 172 GYGLGSGISLFIAT-NICETIVWKAFSPTTVNT 203
            Y + S  S  I T N C  I+WK F  T VNT
Sbjct: 230 SYNIQSHTSSLIETCNQCRLIIWKQFRMTXVNT 132
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|171543827|ref|NP_034193.2| dynein cytoplasmic 1
intermediate chain 1 [Mus musculus]
         (628 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

20271                                                                 283   2e-76
14105                                                                 167   9e-42
12841                                                                 121   1e-27
07741                                                                  57   2e-08
20662                                                                  49   4e-06
08355                                                                  49   7e-06
03387                                                                  46   5e-05
13278                                                                  39   0.006
15972                                                                  36   0.046
02960                                                                  36   0.052
01598                                                                  35   0.10 
13335                                                                  34   0.17 
27475                                                                  33   0.32 
01768                                                                  32   0.74 
05393                                                                  32   1.0  
27465                                                                  31   1.2  
25139                                                                  28   8.0  
>20271
          Length = 567

 Score =  283 bits (723), Expect = 2e-76,   Method: Compositional matrix adjust.
 Identities = 130/188 (69%), Positives = 153/188 (81%)
 Frame = -1

Query: 373 HPVYCVNVVGTQNAHNLITVSTDGKMCSWSLDMLSTPQESMELVYNKSKPVAVTGMAFPT 432
           HPVYC+ VVGTQNAHNLI+VS DGK+CSWSLDMLS PQ+SMEL + +SK VA T  +F +
Sbjct: 567 HPVYCITVVGTQNAHNLISVSNDGKLCSWSLDMLSQPQDSMELQHKQSKSVAATCFSFLS 388

Query: 433 GDVNNFVVGSEEGTVYTACRHGSKAGIGEVFEGHQGPVTGINCHMAVGPIDFSHLFVTSS 492
           GD NNF+VGSEE  VY+A RHGSKAGI E +EGHQGP+T I+ H A G IDFS  F+T+S
Sbjct: 387 GDANNFIVGSEECLVYSASRHGSKAGINEAYEGHQGPITAIDTHHAAGQIDFSPFFLTAS 208

Query: 493 FDWTVKLWTTKHNKPLYSFEDNADYVYDVMWSPVHPALFACVDGMGRLDLWNLNSDTEVP 552
           FDWTVKLW  K  K + SFEDN+DYV DV WSP +PALF+CVD MGRLDLW+LN +TEVP
Sbjct: 207 FDWTVKLWNIKEQKYVCSFEDNSDYVSDVQWSPTNPALFSCVDIMGRLDLWHLNHETEVP 28

Query: 553 TASVAIEG 560
           TASV ++G
Sbjct: 27  TASVVVDG 4
>14105
          Length = 429

 Score =  167 bits (424), Expect = 9e-42,   Method: Compositional matrix adjust.
 Identities = 77/120 (64%), Positives = 92/120 (76%), Gaps = 1/120 (0%)
 Frame = +3

Query: 499 LWTTKHNKPLYSFEDNADYVYDVMWSPVHPALFACVDGMGRLDLWNLNSDTEVPTASVAI 558
           LW+ K  KPLYSFEDN+DYV DV WSPVHPALFA VDG GRLDLWNLN DTEVPTAS+ +
Sbjct: 3   LWSLKDTKPLYSFEDNSDYVMDVAWSPVHPALFAAVDGSGRLDLWNLNQDTEVPTASIVV 182

Query: 559 EGASALNRVRWAQGGKEVAVGDSEGRIWIYDVGE-LAVPHNDEWTRFARTLVEIRANRAD 617
           +GA ALNRV W   G  V +GD  G++++YDV E LA+P  DEW+RF  TL E++ N+ D
Sbjct: 183 DGAPALNRVSWTPSGLHVTIGDESGKLYVYDVAEHLALPTRDEWSRFNATLNELKMNQND 362

 Score = 29.6 bits (65), Expect = 3.9,   Method: Compositional matrix adjust.
 Identities = 18/61 (29%), Positives = 24/61 (39%), Gaps = 1/61 (1%)
 Frame = +3

Query: 310 KFKKTTPEYVFHCQSS-VMSVCFARFHPNLVVGGTYSGQIVLWDNRSHRRTPVQRTPLSA 368
             K T P Y F   S  VM V ++  HP L      SG++ LW+       P     +  
Sbjct: 9   SLKDTKPLYSFEDNSDYVMDVAWSPVHPALFAAVDGSGRLDLWNLNQDTEVPTASIVVDG 188

Query: 369 A 369
           A
Sbjct: 189 A 191
>12841
          Length = 1364

 Score =  121 bits (303), Expect = 1e-27,   Method: Compositional matrix adjust.
 Identities = 84/329 (25%), Positives = 148/329 (44%), Gaps = 25/329 (7%)
 Frame = +1

Query: 268 SKHRVVTCMDWSLQYPELMVASYSNNEDAPHEPDGVALVWNMKFKKTTPEYVFHCQSSVM 327
           +K R V+C+ W+   P+L+   Y    D  ++  G+   W++K     PE V+     V 
Sbjct: 394 TKGRNVSCLAWNKSNPDLVAVGY-GQFDFTNQKSGLICCWSLK-NPEYPERVYTSTHGVT 567

Query: 328 SVCFARFHPNLVVGGTYSGQIVLWDNRSHRRTPVQRTPLSAAAHTHPVYCVNVV------ 381
           S+ F+  + N++  G Y G + +++ RS    P+     +   H  PV+ +  +      
Sbjct: 568 SLDFSVANANILAAGYYDGGVAIYNVRSTSDEPILDNQETHGKHLGPVWQIQWIEKERGS 747

Query: 382 GTQNAHNLITVSTDGKMCSWSLDMLSTPQESMELVYNKSKPVAVTGMA------------ 429
           G + A  LI++STDG++  WS+       ES  ++  K  P  + G A            
Sbjct: 748 GEERAEVLISISTDGRVTQWSI---RKGFESNNIMRLKKLPTRMAGKAREKKGEAFISRH 918

Query: 430 -------FPTGDVNNFVVGSEEGTVYTACRHGSKAGIGEVFEGHQGPVTGINCHMAVGPI 482
                  F + D+N ++ G+EEG ++  C         E + GH  PV     H+   P 
Sbjct: 919 AGGLCFDFHSRDLNVYLAGTEEGYIH-KCSCSYNEQYLETYSGHTAPVY----HIRWSPF 1083

Query: 483 DFSHLFVTSSFDWTVKLWTTKHNKPLYSFEDNADYVYDVMWSPVHPALFACVDGMGRLDL 542
             S +F++ S DW+++LW      P+ +F  +   V+DV WSP    +FACV   G +++
Sbjct: 1084-VSDIFLSCSADWSIRLWHQDRTTPILTFHSSTKTVHDVCWSPRSSTVFACVH-EGAVEV 1257

Query: 543 WNLNSDTEVPTASVAIEGASALNRVRWAQ 571
           W+L   T     ++     + L  V + +
Sbjct: 1258WDLAQSTLDAVITITPTSGAKLTSVTFGK 1344
>07741
          Length = 2119

 Score = 57.0 bits (136), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 44/165 (26%), Positives = 76/165 (46%), Gaps = 17/165 (10%)
 Frame = +1

Query: 438 FVVGSEEGTVYTACRHGSKAGIGEVFEGHQGPVTGINCHMAVGPIDFSH----LFVTSSF 493
           F+VG+EEG V+  C     +   +  + H         +MAV  + ++H    ++ T S 
Sbjct: 157 FLVGTEEGKVH-VCSKAYTSHFIDTLDSH---------NMAVYKVAWNHYHPKIYATCSA 306

Query: 494 DWTVKLW-----------TTKHNKPLYSFEDNADYVYDVMWSPVHPALFACVDGMGRLDL 542
           DW VK+W            +   KPL+SF+ N + V DV W+P    +FA V   G++ +
Sbjct: 307 DWNVKIWENGGKPTDTGXDSLSRKPLFSFDLN-NSVGDVAWAPYSSTVFAAVTADGKVCV 483

Query: 543 WNLNSDTEVPTAS--VAIEGASALNRVRWAQGGKEVAVGDSEGRI 585
           ++L+ +   P     VA +  + L  + +      + VGD  G +
Sbjct: 484 YDLSVNKYEPLCEQMVAQKKKTKLTHIEFNPSYPILIVGDDRGNV 618
>20662
          Length = 1220

 Score = 49.3 bits (116), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 36/133 (27%), Positives = 64/133 (48%), Gaps = 4/133 (3%)
 Frame = +2

Query: 483 DFSHLFVTSSFDWTVKLWTTKHNKPLYSFEDNADYVYDVMWSPVHPALFACVDGMGRLDL 542
           D SH ++++S+D  +K+W T     LY++  ++D V+DV   P  PALF      G++ L
Sbjct: 419 DXSH-YLSASYDHGIKVWNTDLTS-LYTYRAHSDIVWDVQCHPTEPALFLSCSQDGKIVL 592

Query: 543 WNLNSD---TEVPTASVAIEGASALNRVRWAQGGKEV-AVGDSEGRIWIYDVGELAVPHN 598
           W++      T +P  S   +       V+W    + + AVGD  G + + D+  + V  N
Sbjct: 593 WDVRESKPATCLPKCSSGFKPTC----VQWQPNARNMYAVGDEGGHVSVQDL-RMVVEKN 757

Query: 599 DEWTRFARTLVEI 611
             +    R +  +
Sbjct: 758 VSYQSHNRVVTRL 796
>08355
          Length = 498

 Score = 48.9 bits (115), Expect = 7e-06,   Method: Composition-based stats.
 Identities = 43/175 (24%), Positives = 73/175 (41%), Gaps = 18/175 (10%)
 Frame = -1

Query: 344 YSGQIVLWDNRSHRRTPVQRTPLSAAAHTHPVYCV--NVVGTQNAHNLITVSTDGKMCSW 401
           Y G + L++       PVQR       HT PV+ V      + N  N  ++S+DG++  W
Sbjct: 495 YDGSVALFNTIEKHNNPVQRCTADNGKHTDPVWQVRWQKDDSDNNMNFFSISSDGRIVHW 316

Query: 402 S----------LDMLSTPQESMELVYNKSKPVAVTGMAFPTGDVNN--FVVGSEEGTVYT 449
           +          +  L+ P    E        V   G AF      +  F+VG+EEG ++ 
Sbjct: 315 TIVKNEMIYQDIIQLTIPGPPAEGPDGIRMEVTGCGTAFDFHKHKDYLFLVGTEEGKMHV 136

Query: 450 ACRHGSKAGIGEVFEGHQGPVTGINCHMAVGPIDFS----HLFVTSSFDWTVKLW 500
             +  +   IG          +G   +MA+  + ++    +++ T S DW VK+W
Sbjct: 135 CSKAYTSHFIG----------SGDAHNMAIYKVAWNRFHPNVYATCSADWNVKIW 1
>03387
          Length = 1891

 Score = 45.8 bits (107), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 63/255 (24%), Positives = 105/255 (41%), Gaps = 10/255 (3%)
 Frame = +1

Query: 336 PNLVVGGTYSGQIVLWDNRSHRRTP---VQRTP-LSAAAHTHPVYCVNVVGTQNAHNLIT 391
           P ++   T S  ++++D   H   P    +  P L    H    Y ++     N H L++
Sbjct: 241 PCIIATKTPSSDVLVFDYTKHPSKPDPSGECIPELRLKGHQKEGYGLSWNPNLNGH-LLS 417

Query: 392 VSTDGKMCSWSLDMLSTPQES----MELVYNKSKPVAVTGMAFPTGDVNNF-VVGSEEGT 446
            S D  +C W  D+ ST +ES       ++     V V  +A+     + F  V  ++  
Sbjct: 418 ASDDHTICLW--DINSTQRESRVVDAHTIFTGHTSV-VEDVAWHLLHESLFGSVADDQKL 588

Query: 447 VYTACRHGSKAGIGEVFEGHQGPVTGINCHMAVGPIDFSHLFVTSSFDWTVKLWTTKHNK 506
           +    R  + +    V + H   V   NC ++  P     +  T S D TV LW  ++ K
Sbjct: 589 MIWDTRSNTTSKPSHVVDAHTAEV---NC-LSFNPYS-EFILATGSADKTVALWDLRNLK 753

Query: 507 -PLYSFEDNADYVYDVMWSPVHPALFACVDGMGRLDLWNLNSDTEVPTASVAIEGASALN 565
             L+SFE + D ++ V WSP +  + A      RL +W+L+   E      A +G   L 
Sbjct: 754 LKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLHVWDLSKIGEEQLPEDAEDGPPEL- 930

Query: 566 RVRWAQGGKEVAVGD 580
              +  GG    + D
Sbjct: 931 --LFIHGGHTAKISD 969
>13278
          Length = 870

 Score = 38.9 bits (89), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 28/110 (25%), Positives = 52/110 (47%), Gaps = 4/110 (3%)
 Frame = +1

Query: 485 SHLFVTSSFDWTVKLWTTKHNKPLYSFEDNADYVYDVMWSPVHPALFACVDGMGRLD--- 541
           S +  ++SFD TV+LW  +    L++   + + VY V +SP    L +     G  D   
Sbjct: 112 SLILASASFDSTVRLWEVERGLCLHTLTKHQEPVYSVAFSPDGKYLAS-----GSFDKCV 276

Query: 542 -LWNLNSDTEVPTASVAIEGASALNRVRWAQGGKEVAVGDSEGRIWIYDV 590
            +WN+ + + V     + +G   +  V W   G +V    S+G +++ D+
Sbjct: 277 HIWNVQTGSLVH----SYKGTGGIFEVCWNHRGDKVGASASDGSVFVLDL 414
>15972
          Length = 1069

 Score = 36.2 bits (82), Expect = 0.046,   Method: Compositional matrix adjust.
 Identities = 25/85 (29%), Positives = 41/85 (48%)
 Frame = +3

Query: 463 FEGHQGPVTGINCHMAVGPIDFSHLFVTSSFDWTVKLWTTKHNKPLYSFEDNADYVYDVM 522
           F GH+GPV     H+AV P     L +T S D T++LW   + +  +   +  +    V 
Sbjct: 225 FSGHKGPVR----HLAVHP--SGKLTLTVSQDRTLRLWNNMNGRIAF-ISNMKEAAESVR 383

Query: 523 WSPVHPALFACVDGMGRLDLWNLNS 547
           W+P    L+  V     LD++++ S
Sbjct: 384 WAP--GGLYYVVAFRSHLDVYSVES 452
>02960
          Length = 1577

 Score = 35.8 bits (81), Expect = 0.052,   Method: Compositional matrix adjust.
 Identities = 57/257 (22%), Positives = 95/257 (36%), Gaps = 33/257 (12%)
 Frame = +2

Query: 301 DGVALVWNMKFKKTTPEYVFHCQSSVMSVCFARFHPN--LVVGGTYSGQIVLWDNRSH-- 356
           D  ALVW  + +    +    C+    SV      P+   +  G++   + LW    +  
Sbjct: 680 DQTALVWQWQRETNEVDCRLSCRGHAASVDCVAVSPDSQQMCTGSWDKMLKLWSTDCNVD 859

Query: 357 -----------------RRTPVQRTP-LSAAAHTHPVYCVNVVGTQNAHNLITVSTDGKM 398
                            + T   R P L+ + H   V  V  +   + H ++T S D  +
Sbjct: 860 GDQSEDTERPSKKKKSAKSTTQTRVPVLTLSGHAEAVSAVRWL---DPHRVVTSSWDHSL 1030

Query: 399 CSWSL------DMLSTPQESMELVYNKSKPVAVTGMAFPTGDVNNFVVGSEEGTVYTACR 452
             W L       ++   +  +++ Y+    + +TG A    D +  +V          C 
Sbjct: 1031RLWDLHTAQQTSLIQGSKAVLDVAYSPLSHMLITGSA----DRHVRLVDPR-------CS 1177

Query: 453 HGSKAGIGEVFEGHQGPVTGINCHMAVGPIDFS----HLFVTSSFDWTVKLWTTKHNKP- 507
            G        F  H G VTG+         D+S    HLF++ S+D  +KLW T+  K  
Sbjct: 1178EGETVKCA--FTSHTGWVTGV---------DWSPTREHLFLSGSYDNVLKLWDTRSPKAT 1324

Query: 508 LYSFEDNADYVYDVMWS 524
           LY    + D +  V WS
Sbjct: 1325LYDMNWHEDRILAVDWS 1375
>01598
          Length = 1545

 Score = 34.7 bits (78), Expect = 0.10,   Method: Compositional matrix adjust.
 Identities = 38/137 (27%), Positives = 57/137 (41%), Gaps = 3/137 (2%)
 Frame = +1

Query: 463 FEGHQGPVTGINCHMAVGPIDFSHLFVTSSFDWTVKLWTTKHNKPLYSFEDNADYVYDVM 522
           +  H  PV  I    A GP   S    T + D  V LW  +  + + S      +VY V 
Sbjct: 364 YRPHMRPVFNI---CASGPD--SKTLCTFAQDRQVVLWDLETMEAVASMATLGGHVYCVR 528

Query: 523 WSPVHPALFACVDGMGRLDLWNLNSDTEVPTASVAIEG-ASALNRVRWAQGGKE--VAVG 579
            SP+ P   A   G   +  WN+++ T     +   +G  S +  V W    KE  +  G
Sbjct: 529 TSPIDPGRVAVGVGDSMIRTWNMSNKTNPYDVTTLWQGIKSKVTAVAW-HPTKEGWLGFG 705

Query: 580 DSEGRIWIYDVGELAVP 596
             +GRI ++DV    +P
Sbjct: 706 TDDGRIGVFDVLSHKMP 756
>13335
          Length = 863

 Score = 34.3 bits (77), Expect = 0.17,   Method: Compositional matrix adjust.
 Identities = 55/234 (23%), Positives = 86/234 (36%), Gaps = 26/234 (11%)
 Frame = +1

Query: 305 LVWNMKFKKTTPEYVFHCQSSVMSVCFARFHPNL--VVGGTYSGQIVLWDNRSHRRTPVQ 362
           +VW++K      EY  H   S + VC  +F P+   +V G+    I +W+         Q
Sbjct: 7   IVWDVKTGSIKGEYQ-HASKSSIRVC--KFSPSSSHLVSGSDDDTICMWE------VATQ 159

Query: 363 RTPLSAAAHTHPVYCVNVVGTQNAHNLITVSTDGKMCSWSLDM-------LSTPQESMEL 415
           +   S   H   V  + +  + N H L++ S +G +  W           L      + +
Sbjct: 160 KLVRSYVGHEDSV--MALAYSPNGHYLVSGSPNGDLYVWDASFGHCRHLTLRVDAHDLGV 333

Query: 416 VYNKSKPVAVTGMA---------FPTGDVNNFV--------VGSEEGTVYTACRHGSKAG 458
              +  P   T  A           TG  +N +        VGS E T+   CR      
Sbjct: 334 TCCEFSPTFGTACAENSSTCNLLLATGGKDNLIKLWTFSAQVGSPEVTL--QCR------ 489

Query: 459 IGEVFEGHQGPVTGINCHMAVGPIDFSHLFVTSSFDWTVKLWTTKHNKPLYSFE 512
             ++  GH   V      MA      S L  + SFD +V+LW +     L+S E
Sbjct: 490 --DILSGHSDLV------MACAFSPSSALLASGSFDKSVRLWDSVKGVALFSIE 627
>27475
          Length = 369

 Score = 33.1 bits (74), Expect = 0.32,   Method: Compositional matrix adjust.
 Identities = 25/75 (33%), Positives = 34/75 (45%), Gaps = 1/75 (1%)
 Frame = +2

Query: 462 VFEGHQGPVTGINCHMAVGPIDFSHLFVTSSFDWTVKLWTTKHNKP-LYSFEDNADYVYD 520
            F  H G VTG++           HLF++ S+D  +KLW T+  K  LY    + D +  
Sbjct: 53  AFTSHTGWVTGVDWSPTR-----EHLFLSGSYDNVLKLWDTRSPKATLYDMNWHEDRILA 217

Query: 521 VMWSPVHPALFACVD 535
           V WS     L   VD
Sbjct: 218 VDWSIPELLLSGGVD 262
>01768
          Length = 1424

 Score = 32.0 bits (71), Expect = 0.74,   Method: Compositional matrix adjust.
 Identities = 29/120 (24%), Positives = 53/120 (44%), Gaps = 17/120 (14%)
 Frame = +3

Query: 444 EGTVYTAC------------RHGSKAGIGEVFEGHQGPVTGINCHMAVGPIDFSHLFVTS 491
           EG V+ +C            +  SKA +  V E H   +  IN +    PI+  HL  + 
Sbjct: 873 EGNVFASCSVDRTLRIWNTQQKPSKANVLTVPEAHSRDINVINWN----PIE-KHLLASG 1037

Query: 492 SFDWTVKLWTTK--HNKPL---YSFEDNADYVYDVMWSPVHPALFACVDGMGRLDLWNLN 546
             D  +K+W  +   NKP+    SF+ ++  V  + W+P   ++ A      ++ +W+ +
Sbjct: 1038GDDGIIKIWDLRMFRNKPVSAQASFKLHSQPVTSLEWNPQDSSVLAASGEDDQITIWDFS 1217

 Score = 30.4 bits (67), Expect = 2.1,   Method: Compositional matrix adjust.
 Identities = 27/93 (29%), Positives = 39/93 (41%), Gaps = 2/93 (2%)
 Frame = +3

Query: 500 WTTKHNKPLYSFEDNADYVYDVMWSPVHPALFACVDGMGRLDLWNLNSDTEVPTASVAIE 559
           WTT+ +    S+  + D V DV WSP    +FA       L +WN              E
Sbjct: 804 WTTEKS----SYAAHTDSVEDVQWSPNEGNVFASCSVDRTLRIWNTQQKPSKANVLTVPE 971

Query: 560 GASA-LNRVRWAQGGKE-VAVGDSEGRIWIYDV 590
             S  +N + W    K  +A G  +G I I+D+
Sbjct: 972 AHSRDINVINWNPIEKHLLASGGDDGIIKIWDL 1070
>05393
          Length = 904

 Score = 31.6 bits (70), Expect = 1.0,   Method: Compositional matrix adjust.
 Identities = 24/93 (25%), Positives = 41/93 (44%), Gaps = 7/93 (7%)
 Frame = +1

Query: 466 HQGPVTGINCHMA-VGPIDFSH----LFVTSSFDWTVKLWTTKHNKPLYSFEDNADY--V 518
           H+ PV  +  H + V  +  S     L +T+S D T+K+W  + +KP + F  N     +
Sbjct: 187 HEKPVFSVGAHSSCVTGVCLSSQIPGLMITTSEDKTMKVWDIQDDKPTHVFSRNLKMKEL 366

Query: 519 YDVMWSPVHPALFACVDGMGRLDLWNLNSDTEV 551
           +     P  P +FA   G     +W++     V
Sbjct: 367 HCTGCCPEAPFVFAVGGGRREPKVWDIRESAAV 465
>27465
          Length = 658

 Score = 31.2 bits (69), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 29/103 (28%), Positives = 47/103 (45%), Gaps = 2/103 (1%)
 Frame = -1

Query: 425 VTGMAFPTGDVNNFVVGSEEGTVYTACRHGSKAGIGEV--FEGHQGPVTGINCHMAVGPI 482
           +T +AF     ++F+ GS + T    C+    A   E+   EGH+  V  I  +    P 
Sbjct: 352 LTNVAFNKSG-SSFITGSYDRT----CKIWDTASAEELHTLEGHRNVVYAIAFN---NP- 200

Query: 483 DFSHLFVTSSFDWTVKLWTTKHNKPLYSFEDNADYVYDVMWSP 525
            F    +T SFD T KLW+T   K  ++   +   +  V ++P
Sbjct: 199 -FGDKVITGSFDKTCKLWSTADGKCYHTLRGHTAEIVCVSFNP 74
>25139
          Length = 657

 Score = 28.5 bits (62), Expect = 8.0,   Method: Compositional matrix adjust.
 Identities = 19/74 (25%), Positives = 31/74 (41%), Gaps = 7/74 (9%)
 Frame = +2

Query: 239 SGRELEEKDGDVQAGANLSF-------NRQFYDEHWSKHRVVTCMDWSLQYPELMVASYS 291
           S  +L E     ++ A+LSF       +  F+  H   H  + C   S   P+L+  + S
Sbjct: 245 SLNKLXEHHSQPKSSAHLSFPLSLVHLHSVFHSTHCPSHFFLFCPSPSSPXPQLVKGTTS 424

Query: 292 NNEDAPHEPDGVAL 305
            N   PH P  + +
Sbjct: 425 RNVIPPHPPFAITI 466
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31542111|ref|NP_038786.2| adducin 3 (gamma) [Mus
musculus]
         (706 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

08503                                                                 248   2e-76
12858                                                                 197   7e-59
06772                                                                  47   3e-08
37713                                                                  30   4.2  
>08503
          Length = 985

 Score =  248 bits (632), Expect(2) = 2e-76,   Method: Compositional matrix adjust.
 Identities = 114/222 (51%), Positives = 162/222 (72%)
 Frame = +3

Query: 116 VTPINDLPGADTSSYVKGEKLTRCKLASLYRLADLFGWAHLANTYISVRISKEQDHIIII 175
           V P+ND+ G +T  Y K EK+ RCKLA+ YRL DLF W +  + +IS+R+S+EQ+  ++ 
Sbjct: 138 VIPVNDIRGVETFGYSKQEKVLRCKLAACYRLIDLFXWTNGIHDHISMRVSQEQEQFLVN 317

Query: 176 PRGLSFSEATASTLVKVNIIGEVVDQGSTDLKIDHTGFSPHAAIYSTRPDVKCVIHIHTL 235
           P G+ +SE TASTL KV++ GEVVD GST L I   GF+ H+A++  RPD++C+IH+HT 
Sbjct: 318 PHGMLYSEMTASTLAKVDVRGEVVDTGSTGLGISKAGFTLHSALHQARPDLRCIIHLHTA 497

Query: 236 ATAAVSSMKCGILPISQESLILGDVAYYDYQGSLDEEEERIELQKVLGPSCKVLVLRNHG 295
              AVS+ KCG+LPISQE++I G ++Y+DY G L ++E+R +L + LGP  KV+ LRNHG
Sbjct: 498 NVVAVSATKCGLLPISQEAMICGKISYHDYPGPLTDQEDRDQLGRCLGPFNKVMFLRNHG 677

Query: 296 MVALGETLEEAFHYIFNVQMACEIQVQAVAGAGGVDNLLVLD 337
           ++  GET+EEAFHY FNV  A E QV+ +    G+DNL+++D
Sbjct: 678 VLVCGETIEEAFHYAFNVMAAVETQVKVM--VVGLDNLILVD 797

 Score = 57.4 bits (137), Expect(2) = 2e-76,   Method: Compositional matrix adjust.
 Identities = 21/44 (47%), Positives = 35/44 (79%)
 Frame = +2

Query: 359 ASHQKWKVGEIEFEGLMRTLDNLGYRTGYAYRHPLVREKPRHKS 402
            S ++W+ GE+E+E LMRTLDN GYRTG+ Y+ PL++++ + ++
Sbjct: 854 TSSRRWRCGELEWEALMRTLDNSGYRTGHLYKQPLMKQEKKERT 985
>12858
          Length = 851

 Score =  197 bits (500), Expect(2) = 7e-59,   Method: Compositional matrix adjust.
 Identities = 94/197 (47%), Positives = 142/197 (72%), Gaps = 2/197 (1%)
 Frame = +1

Query: 212 GFSPHAAIYSTRPDVKCVIHIHTLATAAVSSMKCGILPISQESLILGDVAYYDYQGSLDE 271
           GF+ H+AI+  RPD++C+IH+HT A  AVS+ K G+LP+S ++L+ G V+Y+DY G L +
Sbjct: 1   GFTLHSAIHQARPDIRCIIHLHTPAAVAVSATKQGLLPVSHQALMCGKVSYHDYNGILVD 180

Query: 272 EEERIELQKVLGPSCKVLVLRNHGMVALGETLEEAFHYIFNVQMACEIQVQAVAGAGGVD 331
           +EER +L + LGP  KV+ LRNHG+V  GE++EEAFH+ FNV  AC++Q++ +    G+D
Sbjct: 181 QEERDQLARNLGPFNKVMFLRNHGVVTCGESIEEAFHFAFNVMAACDVQMKVM--PVGID 354

Query: 332 NLLVLDLQKYKAFTHGVAMSGGGGVNMASHQKWKVGEIEFEGLMRTLDNLGYRTGYAYRH 391
           NL++LD ++ +  T+      G     +S +KW+ GE+EFE LMRTLDN GYRTG+ Y+ 
Sbjct: 355 NLVLLD-EETQEKTYKAGRQTGTD---SSGRKWRCGELEFEALMRTLDNSGYRTGHVYKQ 522

Query: 392 PLVREKPRHK--SDVEI 406
           PL++++ + K  SDVE+
Sbjct: 523 PLMKQEKKEKMNSDVEV 573

 Score = 49.7 bits (117), Expect(2) = 7e-59,   Method: Compositional matrix adjust.
 Identities = 32/89 (35%), Positives = 47/89 (52%), Gaps = 4/89 (4%)
 Frame = +3

Query: 413 FSFEDD---SAPLSPLKFMAQRQ-QREKTRWLNSPNTYMKVNVPEESRNGETSPRTKITW 468
           + F+ D   S  +SPLK   +RQ Q  K  WL SPN Y K  + E    G T+P+    W
Sbjct: 597 YIFDGDYEHSKYISPLKLAMERQKQAYKAGWLTSPNAYKKQEIEE---IGTTTPKKITKW 767

Query: 469 MKAEDSSKVSSGTPIKIEDPNQFVPLNTN 497
           +   +++   + T IK+++PNQF P   N
Sbjct: 768 VPGGEATDQKT-TAIKVDNPNQFAPQGVN 851
>06772
          Length = 996

 Score = 46.6 bits (109), Expect(2) = 3e-08,   Method: Compositional matrix adjust.
 Identities = 22/53 (41%), Positives = 34/53 (64%)
 Frame = +2

Query: 481 TPIKIEDPNQFVPLNTNPTEVLEKRNKIREQNRYDLKTAGPQSQLLAGIVVDK 533
           T IK+E+PNQF P  +NP E  +K+  I++    +  +AGP S++L GI  D+
Sbjct: 170 TAIKVENPNQFAPQGSNPKEFRDKQKSIKKDYYEERVSAGPTSKILDGISWDE 328

 Score = 29.6 bits (65), Expect(2) = 3e-08,   Method: Compositional matrix adjust.
 Identities = 19/46 (41%), Positives = 23/46 (50%), Gaps = 1/46 (2%)
 Frame = +1

Query: 424 PLKFMAQRQ-QREKTRWLNSPNTYMKVNVPEESRNGETSPRTKITW 468
           PL    +RQ Q  K  WL SPNTY K  + E    G T+P+    W
Sbjct: 7   PLXTAMERQKQAYKAGWLTSPNTYQKHEIEE---IGTTTPKKITKW 135
>37713
          Length = 2148

 Score = 29.6 bits (65), Expect = 4.2,   Method: Compositional matrix adjust.
 Identities = 14/27 (51%), Positives = 16/27 (59%)
 Frame = -2

Query: 228  CVIHIHTLATAAVSSMKCGILPISQES 254
            C+IHIHTL +   S  K  IL I QE 
Sbjct: 1565 CIIHIHTLKSHXSSCFKANILIIDQEC 1485
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|13385002|ref|NP_079840.1| mago-nashi homolog [Mus
musculus]
         (146 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

31130                                                                 278   4e-76
>31130
          Length = 487

 Score =  278 bits (712), Expect = 4e-76,   Method: Compositional matrix adjust.
 Identities = 132/145 (91%), Positives = 138/145 (95%)
 Frame = +2

Query: 2   GSDFYLRYYVGHKGKFGHEFLEFEFRPDGKLRYANNSNYKNDVMIRKEAYVHKSVMEELK 61
            SDFYLRYYVGHKGKFGHEFLEFEFRPDGKLRYANNSNYKND MIRKEAYVHKSVMEELK
Sbjct: 8   SSDFYLRYYVGHKGKFGHEFLEFEFRPDGKLRYANNSNYKNDTMIRKEAYVHKSVMEELK 187

Query: 62  RIIDDSEITKEDDALWPPPDRVGRQELEIVIGDEHISFTTSKIGSLIDVNQSKDPEGLRV 121
           R+I+DSE+ +EDDALWP PDRVGRQELEIVIGDEHISFTTSKIGSL+DVNQSKDPEGLR 
Sbjct: 188 RLIEDSEVMQEDDALWPSPDRVGRQELEIVIGDEHISFTTSKIGSLVDVNQSKDPEGLRT 367

Query: 122 FYYLVQDLKCLVFSLIGLHFKIKPI 146
           FYYLVQDL  +VFSLIGLHFKIKPI
Sbjct: 368 FYYLVQDLNVVVFSLIGLHFKIKPI 442
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|11230802|ref|NP_068695.1| actinin alpha 4 [Mus
musculus]
         (912 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

19002                                                                 282   5e-76
17613                                                                 189   2e-71
19147                                                                 189   2e-49
29426                                                                 114   2e-25
29446                                                                  97   4e-20
05733                                                                  81   2e-15
34417                                                                  72   7e-13
32371                                                                  49   3e-10
14594                                                                  59   7e-09
01375                                                                  50   4e-06
09711                                                                  50   5e-06
18202                                                                  49   7e-06
32088                                                                  40   0.004
18556                                                                  40   0.005
28965                                                                  40   0.005
04951                                                                  39   0.007
38338                                                                  38   0.016
38533                                                                  38   0.021
20251                                                                  37   0.025
03732                                                                  32   0.92 
22703                                                                  31   2.5  
02929                                                                  30   5.4  
>19002
          Length = 842

 Score =  282 bits (721), Expect = 5e-76,   Method: Compositional matrix adjust.
 Identities = 147/283 (51%), Positives = 190/283 (67%), Gaps = 8/283 (2%)
 Frame = -2

Query: 81  DGLKLMLLLEVISGERLPKPERGKMRVHKINNVNKALDFIASKGVKLVSIGAEEIVDGNA 140
           DG  LM LLEV     +    +GKMR+H + NV+KAL F+  + V L ++GA +IVDG++
Sbjct: 841 DGKMLMKLLEVRVRGEIASDXKGKMRIHCLENVDKALTFLHEQRVHLENMGAHDIVDGSS 662

Query: 141 KMTLGMIWTIILRFAIQDISVEET------SAKEGLLLWCQRKTAPYKNVNVQNFHISWK 194
           ++TLG+IWTIILRF IQDI +EE       SAK+ LLLWCQ KTA Y NVNV+NF  SW+
Sbjct: 661 RLTLGLIWTIILRFQIQDIMIEEVDNSETKSAKDALLLWCQMKTAGYPNVNVRNFTTSWR 482

Query: 195 DGLAFNALIHRHRPELIEYDKLRKDDPVTNLNNAFEVAEKYLDIPKMLDAEDIVNTARPD 254
           DGLAFNA+IH+HRP+L++YD+L K   + NL NAF VAE  L +  +L+ ED VN   PD
Sbjct: 481 DGLAFNAIIHKHRPDLVQYDRLHKSSAIQNLQNAFTVAEDKLGLTALLEPED-VNVEYPD 305

Query: 255 EKAIMTYVSSFYHAFSGAQKAETAANRICKVL--AVNQENEHLMEDYERLASDLLEWIRR 312
           EK+I+TYV ++YH FS  +       RI KV+  A+N EN   +E+YE L SDLLEWI +
Sbjct: 304 EKSIITYVVTYYHYFSKMKADSVQGKRIGKVIDNAINTENS--IEEYETLTSDLLEWIEQ 131

Query: 313 TIPWLEDRVPQKTIQEMQQKLEDFRDYRRVHKPPKVQEKCQLE 355
           TI  L DR    ++  +QQ+L  F  YR V KPPK  EK  LE
Sbjct: 130 TIVILRDRQFANSLTGVQQQLAAFNTYRIVEKPPKFDEKGNLE 2
>17613
          Length = 1108

 Score =  184 bits (467), Expect(2) = 2e-71,   Method: Compositional matrix adjust.
 Identities = 87/133 (65%), Positives = 107/133 (80%)
 Frame = +3

Query: 234 KYLDIPKMLDAEDIVNTARPDEKAIMTYVSSFYHAFSGAQKAETAANRICKVLAVNQENE 293
           K+LDIP+MLD ED+VN+A+PDE+++M YVSS+YHAFSGAQ+AETAANRICKVL VNQENE
Sbjct: 390 KHLDIPRMLDPEDMVNSAKPDERSVMAYVSSYYHAFSGAQQAETAANRICKVLKVNQENE 569

Query: 294 HLMEDYERLASDLLEWIRRTIPWLEDRVPQKTIQEMQQKLEDFRDYRRVHKPPKVQEKCQ 353
            LME+YERLASDLLEWIRRT PWLE+RV   T+   + KL++FRDYRR  KPP  + +  
Sbjct: 570 RLMEEYERLASDLLEWIRRTRPWLENRVTDNTLPGTRHKLDEFRDYRRKQKPPSWRTR-- 743

Query: 354 LEINFNTLQTKLR 366
              ++ TL T  R
Sbjct: 744 --PSWRTLSTPCR 776

 Score =  104 bits (260), Expect(2) = 2e-71,   Method: Compositional matrix adjust.
 Identities = 60/133 (45%), Positives = 75/133 (56%), Gaps = 4/133 (3%)
 Frame = +1

Query: 105 MRVHKINNVNKALDFI----ASKGVKLVSIGAEEIVDGNAKMTLGMIWTIILRFAIQDIS 160
           MR HKI NVNKALD+I       G+             + +  L     +          
Sbjct: 4   MRFHKIANVNKALDYIDLQRGQTGLHRSRRNC*RQRKDDIRYDLDNYPQV----CHPRHH 171

Query: 161 VEETSAKEGLLLWCQRKTAPYKNVNVQNFHISWKDGLAFNALIHRHRPELIEYDKLRKDD 220
              T  +   ++    KTAPYKNVNVQNFH+S+KDGLAF ALIHRHRPELI+Y  L KD+
Sbjct: 172 SRRTHCQRRTVIVVPAKTAPYKNVNVQNFHLSFKDGLAFCALIHRHRPELIDYHSLSKDN 351

Query: 221 PVTNLNNAFEVAE 233
           P+ NLN AF++AE
Sbjct: 352 PLENLNTAFDIAE 390

 Score =  189 bits (480), Expect = 5e-48,   Method: Compositional matrix adjust.
 Identities = 86/128 (67%), Positives = 111/128 (86%)
 Frame = +2

Query: 346 PKVQEKCQLEINFNTLQTKLRLSNRPAFMPSEGRMVSDINNGWQHLEQAEKGYEEWLLNE 405
           PK+++K +LE +FNTLQT+LRLSNRPA++P+EG+MVSDI N W+ LE AEKG+EEWLL+E
Sbjct: 725 PKLEDKAKLENSFNTLQTRLRLSNRPAYLPTEGKMVSDIANAWKGLEHAEKGFEEWLLSE 904

Query: 406 IRRLERLDHLAEKFRQKASIHEAWTDGKEAMLKQRDYETATLSDIKALIRKHEAFESDLA 465
           ++RLERLDHLA+KFR K  IHE W+ GKE ML+ RD++   L+++KA+ +KHEAFESDLA
Sbjct: 905 LQRLERLDHLAQKFRHKCEIHEEWSQGKEDMLQSRDFKQCRLNELKAMKKKHEAFESDLA 1084

Query: 466 AHQDRVEQ 473
           AHQDRVEQ
Sbjct: 1085AHQDRVEQ 1108

 Score =  114 bits (284), Expect = 3e-25,   Method: Compositional matrix adjust.
 Identities = 54/65 (83%), Positives = 57/65 (87%)
 Frame = +2

Query: 121 ASKGVKLVSIGAEEIVDGNAKMTLGMIWTIILRFAIQDISVEETSAKEGLLLWCQRKTAP 180
            SKGVKLVSIGAEEIVDGN KMTLGMIWTIILRFAIQDI+VEE +AKEGLLLWCQRK  P
Sbjct: 53  TSKGVKLVSIGAEEIVDGNVKMTLGMIWTIILRFAIQDITVEELTAKEGLLLWCQRKQHP 232

Query: 181 YKNVN 185
            K + 
Sbjct: 233 TKMLT 247
>19147
          Length = 474

 Score =  189 bits (479), Expect(2) = 2e-49,   Method: Compositional matrix adjust.
 Identities = 91/113 (80%), Positives = 99/113 (87%)
 Frame = +1

Query: 118 DFIASKGVKLVSIGAEEIVDGNAKMTLGMIWTIILRFAIQDISVEETSAKEGLLLWCQRK 177
            +IASKGVKLVSIGAEEIVDGN KMTLGMIWTIILRFAIQDI+VEE +AKEGLLLWCQRK
Sbjct: 46  SYIASKGVKLVSIGAEEIVDGNVKMTLGMIWTIILRFAIQDITVEELTAKEGLLLWCQRK 225

Query: 178 TAPYKNVNVQNFHISWKDGLAFNALIHRHRPELIEYDKLRKDDPVTNLNNAFE 230
           TAPYKNVNVQNFH+S+KDGLAF ALIHRHRPELI+Y  L K   V+ LN   +
Sbjct: 226 TAPYKNVNVQNFHLSFKDGLAFCALIHRHRPELIDYHSLSK---VSLLNTVVQ 375

 Score = 26.6 bits (57), Expect(2) = 2e-49,   Method: Composition-based stats.
 Identities = 12/16 (75%), Positives = 13/16 (81%)
 Frame = +3

Query: 104 KMRVHKINNVNKALDF 119
           KMR HKI NVNKAL+ 
Sbjct: 3   KMRFHKIANVNKALEL 50
>29426
          Length = 361

 Score =  114 bits (286), Expect = 2e-25,   Method: Compositional matrix adjust.
 Identities = 54/121 (44%), Positives = 86/121 (71%), Gaps = 1/121 (0%)
 Frame = -2

Query: 557 IVHTIEEIEGLISAHDQFKSTLPDADREREAILAIHKEAQRIAESNHIKLSGSNPYTTVT 616
           IVHT EE+EGL+ AH+QFK+TL +AD+E   I+++ +E   + +   +     NPYTT+ 
Sbjct: 360 IVHTTEEVEGLVDAHEQFKATLGEADKEYSTIVSLSQEVASLGQQYDLT-PPDNPYTTLH 184

Query: 617 PQ-IINSKWEKVQQLVPKRDHALLEEQSKQQSNEHLRRQFASQANMVGPWIQTKMEEIGR 675
            Q  I +KW +V++LVP+RD  L +E ++QQ+NE LRRQFA++AN VG WI+++++ +  
Sbjct: 183 AQEDITNKWSEVRELVPRRDQTLQQEMTRQQNNERLRRQFATKANTVGQWIESQLDAVAS 4

Query: 676 I 676
           +
Sbjct: 3   L 1
>29446
          Length = 1445

 Score = 96.7 bits (239), Expect = 4e-20,   Method: Compositional matrix adjust.
 Identities = 59/165 (35%), Positives = 89/165 (53%), Gaps = 11/165 (6%)
 Frame = +3

Query: 40   DRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIDEDFRDGLKLMLLLEVISGERLPK 99
            +R+L  D  W+  Q+ TFT W N HLR     I +++ DF DGL+L+ L+EV+SG++   
Sbjct: 963  ERELAEDAQWKIIQKNTFTRWANEHLRTVNKAIADLESDFSDGLRLVALIEVLSGKKFKH 1142

Query: 100  P-ERGKMRVHKINNVNKALDFIA-SKGVKLVSIGAEEIVDGNAKMTLGMIWTIILRFAIQ 157
              +R   R  K+ NV   L F+   +G+++V+I + +IVD   K+ LG+IWT+IL ++I 
Sbjct: 1143 VNKRPNFRTQKLENVTLTLKFLEDDEGIRIVNIDSTDIVDKKLKLILGLIWTLILHYSIS 1322

Query: 158  --DISVEETSAKEG-------LLLWCQRKTAPYKNVNVQNFHISW 193
                  EE +  EG       LL W Q K      +  Q  H  W
Sbjct: 1323 MPMWEGEEPTPSEGGPTPKQRLLNWIQSKVP----IAHQELHHRW 1445
>05733
          Length = 1021

 Score = 81.3 bits (199), Expect = 2e-15,   Method: Compositional matrix adjust.
 Identities = 42/102 (41%), Positives = 59/102 (57%), Gaps = 2/102 (1%)
 Frame = +2

Query: 170 LLLWCQR--KTAPYKNVNVQNFHISWKDGLAFNALIHRHRPELIEYDKLRKDDPVTNLNN 227
           LL WCQR      Y+ V++ +F  SW+ GLAF ALIH  RP LI    L + + V N   
Sbjct: 470 LLRWCQRVLNXGTYRGVHIIDFTSSWRSGLAFCALIHAFRPHLISPASLMECETVKNNQL 649

Query: 228 AFEVAEKYLDIPKMLDAEDIVNTARPDEKAIMTYVSSFYHAF 269
           AF+VA+K L I  ++  ED+   A PD+  ++ Y+S F+  F
Sbjct: 650 AFDVAQKELGIAPVMRGEDMAACAVPDKLTMVAYLSQFHELF 775
>34417
          Length = 1096

 Score = 72.4 bits (176), Expect = 7e-13,   Method: Compositional matrix adjust.
 Identities = 33/75 (44%), Positives = 44/75 (58%)
 Frame = +2

Query: 192 SWKDGLAFNALIHRHRPELIEYDKLRKDDPVTNLNNAFEVAEKYLDIPKMLDAEDIVNTA 251
            W +GLAF ALIH   P+  +Y +L+  +   N   AF+ AEK  DI  +LD ED++   
Sbjct: 44  CWNNGLAFCALIHHFYPDAFDYSQLQPQNRRYNFELAFDTAEKLADISPLLDVEDMIKMK 223

Query: 252 RPDEKAIMTYVSSFY 266
            PD K + TYV SFY
Sbjct: 224 NPDWKCVFTYVQSFY 268
>32371
          Length = 625

 Score = 48.5 bits (114), Expect(2) = 3e-10,   Method: Compositional matrix adjust.
 Identities = 24/48 (50%), Positives = 33/48 (68%)
 Frame = -2

Query: 208 PELIEYDKLRKDDPVTNLNNAFEVAEKYLDIPKMLDAEDIVNTARPDE 255
           P+LI+YD L K++ + N N AF VAE+ LDIP  L+A D+V    PD+
Sbjct: 549 PDLIDYDSLSKENVLYNNNLAFTVAEQELDIPAFLEAADMVALRTPDK 406

 Score = 35.0 bits (79), Expect(2) = 3e-10,   Method: Composition-based stats.
 Identities = 12/25 (48%), Positives = 21/25 (84%)
 Frame = -1

Query: 183 NVNVQNFHISWKDGLAFNALIHRHR 207
           +V++++  +SW++GLAF A+IHR R
Sbjct: 625 SVDIKDLLVSWRNGLAFCAIIHRFR 551
>14594
          Length = 1014

 Score = 59.3 bits (142), Expect = 7e-09,   Method: Compositional matrix adjust.
 Identities = 36/109 (33%), Positives = 63/109 (57%), Gaps = 2/109 (1%)
 Frame = +3

Query: 763 ISQEQMQEFRASFNHFDKDHGGALGPEEFKACLISLGYD-VENDRQGDAEFNRIMSVVDP 821
           ++ EQ+ EF+ +F+ FDKD  G +   E    + SLG +  EN+ Q       +++ VD 
Sbjct: 423 LTDEQVAEFKEAFSLFDKDGDGTITTSELGTVMRSLGQNPTENELQ------DMINEVDA 584

Query: 822 NHSGLVTFQAFIDFMSRETTDTDTADQVIASFKVLAGDKN-FITAEELR 869
           + +G + F+ F+  M+R+  DTD  +++  +F+V   D N +I+A ELR
Sbjct: 585 DGNGTIDFEEFLHMMARKMKDTDCEEELREAFRVFDKDGNGYISAAELR 731
>01375
          Length = 2323

 Score = 50.1 bits (118), Expect = 4e-06,   Method: Composition-based stats.
 Identities = 28/71 (39%), Positives = 42/71 (59%), Gaps = 3/71 (4%)
 Frame = +1

Query: 840 TTDTDTADQVIASFKVL-AGDKNFITAEELRRELPPDQAEYCIARMAPY--QGPDAAPGA 896
           T +  ++ +V  +F+ L +G+K FITA+EL   L  +QA+YCI RM PY  +     P A
Sbjct: 4   TENVQSSSEVEQAFRALTSGEKPFITAQELYANLTKEQADYCIGRMQPYVDKTGRTIPDA 183

Query: 897 LDYKSFSTALY 907
            DY  F+  L+
Sbjct: 184 YDYVDFTRQLF 216
>09711
          Length = 3041

 Score = 49.7 bits (117), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 65/268 (24%), Positives = 114/268 (42%), Gaps = 25/268 (9%)
 Frame = +1

Query: 50   EKQQRKTFTAWCNSHLRKAGTQIENIDEDFRDGLKLMLLLEVIS------GERLPKPERG 103
            E ++ KT+  W NS        + ++  D  DGL +  L + I        +   K  + 
Sbjct: 841  ESREEKTYRNWMNS--LGVSPFVHHLYSDLYDGLIIFQLYDYIQPGLVDWSKVKKKFNKL 1014

Query: 104  KMRVHKINNVNKALDF---IASKGVKLVSIGAEEIVDGNAKMTLGMIWTIILRFAIQDIS 160
            K R  +I N N A++    +    VKLV I  ++I+DGN  +TLG++W ++  + +  +S
Sbjct: 1015 KARFERIENCNYAVELGPQVKLVKVKLVGIAGQDILDGNPVLTLGLVWQLMRAYTLAILS 1194

Query: 161  -VEETS---AKEGLLLWCQRKTAPYKNVNVQNFH-ISWKDGLAFNALIHRHRPELIEYDK 215
             + E +   +   ++ W   K    K+  +  F      DG+    +I   +P ++ +D 
Sbjct: 1195 KITENNKPISDNEIITWVNSKIK--KDDRISGFQDRKLNDGVIVARVIEAIKPGIVNWDN 1368

Query: 216  LRKD-----DPVTNLNNAFEVAEKYLDIPKMLDAEDIVNTARPDEKAIMTYVSSFYHAFS 270
            +        D +TN   A  +A K       L  EDIV   +P  K ++T  +       
Sbjct: 1369 IDCSARDYQDRLTNARYAIGLARKIGAGVYAL-PEDIVEV-KP--KMLLTVFACLMMRDF 1536

Query: 271  GAQKAETAAN------RICKVLAVNQEN 292
             ++ A   AN       +C+ L VN E 
Sbjct: 1537 SSRPAAAEANSH*VWDNVCE*LGVNTEG 1620

 Score = 37.7 bits (86), Expect = 0.020,   Method: Compositional matrix adjust.
 Identities = 35/137 (25%), Positives = 55/137 (40%), Gaps = 17/137 (12%)
 Frame = +1

Query: 53  QRKTFTAWCNSHLRKA------------GTQIENIDEDFRDGLKLMLLLE-----VISGE 95
           ++K F  W N HL               GTQ+        DG+ L  L+       I   
Sbjct: 52  EQKAFAEWINRHLSDXPDCKHLLPLDADGTQLFG---QMADGVLLCKLINHSVSNTIDER 222

Query: 96  RLPKPERGKMRVHKINNVNKALDFIASKGVKLVSIGAEEIVDGNAKMTLGMIWTIILRFA 155
            + K      R H+  N+  A++   + G   V+IG E++  G   + LG++W II    
Sbjct: 223 TINKQNLSLYRRHE--NLTLAVNSAGAIGCTTVNIGPEDLAAGRPHLVLGLLWQIIRIGL 396

Query: 156 IQDISVEETSAKEGLLL 172
           + DI++        LLL
Sbjct: 397 LSDINLAHHPGLVNLLL 447
>18202
          Length = 424

 Score = 49.3 bits (116), Expect = 7e-06,   Method: Composition-based stats.
 Identities = 35/127 (27%), Positives = 68/127 (53%), Gaps = 6/127 (4%)
 Frame = -1

Query: 55  KTFTAWCNSHLRKAGTQIENIDEDFRDGLKLMLLLEVISGER-LPKPERGKMRVHKINNV 113
           + + +W NS L +  + +EN+    ++G  L  L++V++ E  L    +   +  +   +
Sbjct: 385 QVYLSWANSVLCEVNSSVENVSS-IQEGRVLCELIDVLAPEAGLLDKVQASGKSGQRAFI 209

Query: 114 NKALDFIASKGVKLVSIGAEEIVDGNAKMTLGMIWTIILRFAIQDI---SVEET--SAKE 168
             ALD + + G+K+V    ++I+DG+ K  L ++W +IL + I  I   S + +  + K+
Sbjct: 208 YAALDHMKNHGIKIV-FSTQDIMDGDIKSLLDVMWLLILNYGIHFIGNNSFQRSVGAGKK 32

Query: 169 GLLLWCQ 175
            LL WCQ
Sbjct: 31  NLLDWCQ 11
>32088
          Length = 1928

 Score = 40.0 bits (92), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 29/121 (23%), Positives = 56/121 (46%), Gaps = 12/121 (9%)
 Frame = +1

Query: 53   QRKTFTAWCNSHLR---------KAGTQIENIDEDFRDGLKLMLLLEVISGERLPKPERG 103
            ++K F AW N HL+         +   + +++ +   DG+ L  L+       + +    
Sbjct: 1264 EQKAFAAWINRHLKDDPDCKHLMEVNEEGDDLFKKVGDGILLCKLINHSVSNTIDERAIN 1443

Query: 104  KMRV---HKINNVNKALDFIASKGVKLVSIGAEEIVDGNAKMTLGMIWTIILRFAIQDIS 160
            K  +   H+  N+  A++   S G   V+IG E++  G   + LG++W II    + DI+
Sbjct: 1444 KSNLNVYHRHENLTLAVNSAGSIGCTTVNIGPEDLAAGRPHLVLGLLWQIIRIGLLSDIN 1623

Query: 161  V 161
            +
Sbjct: 1624 L 1626
>18556
          Length = 799

 Score = 40.0 bits (92), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 26/104 (25%), Positives = 48/104 (46%), Gaps = 1/104 (0%)
 Frame = +2

Query: 169 GLLLWCQRKTAPYK-NVNVQNFHISWKDGLAFNALIHRHRPELIEYDKLRKDDPVTNLNN 227
            LL W   + A Y+    ++     +++G    ALI R RP+LI+Y   +   P+     
Sbjct: 44  SLLRWISVQLAAYQFTAELKEPSDVFRNGRVLCALISRFRPDLIDYAATKDMSPLECNEL 223

Query: 228 AFEVAEKYLDIPKMLDAEDIVNTARPDEKAIMTYVSSFYHAFSG 271
           AF V E+ L I +++ A+  ++    + +  + Y+      F G
Sbjct: 224 AFAVLERELHIDRIMSAKQSLDLNDVESRVWLNYMDQICELFRG 355
>28965
          Length = 421

 Score = 39.7 bits (91), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 35/118 (29%), Positives = 53/118 (44%), Gaps = 2/118 (1%)
 Frame = +2

Query: 356 INFNTLQTKLRLSNRPAFMPSEGRMVSDINNGWQHLEQAEKGYEEWLLNEIRRLERL--D 413
           +  NTL  +L     P       +   ++N  W+ L Q            + R ERL   
Sbjct: 35  VEVNTLAEQLVTDGHPEEETIRQKQ-EEVNEAWKRLRQLS----------LLRQERLYGA 181

Query: 414 HLAEKFRQKASIHEAWTDGKEAMLKQRDYETATLSDIKALIRKHEAFESDLAAHQDRV 471
           H  ++F + A    AW   K+A+L   DY    L+ ++ L RKHE  E DLAA +++V
Sbjct: 182 HEIQRFNRDADETIAWIQEKDAVLSTDDY-GRDLASVQTLQRKHEGVERDLAALEEKV 352
>04951
          Length = 2852

 Score = 39.3 bits (90), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 43/173 (24%), Positives = 76/173 (43%), Gaps = 16/173 (9%)
 Frame = +1

Query: 125 VKLVSIGAEEIVDGNAKMTLGMIWTIILRFAIQDISVEETSAK----EGLLLWCQRKTAP 180
           +KLV IG ++I DGN  +TLG++W ++  + +  +S      K      ++ W   K   
Sbjct: 61  MKLVGIGGKDIHDGNPVLTLGLVWQLMRAYTLAILSKLTEDKKPIQDSEIVDWVNSKVK- 237

Query: 181 YKNVNVQNFHIS-WKDGLAFNALIHRHRPELIEYDKLR-----KDDPVTNLNNAFEVAEK 234
            K+  + +F  S   DG+    +I   +P ++ ++ +       DD + N   A  +A K
Sbjct: 238 -KDERIGSFQDSKLNDGVIVAKVIESIKPGIVNWENINPNASEPDDRLANARYAIGLARK 414

Query: 235 YLDIPKMLDAEDIVNTARPDEKAIMTYVSSFY------HAFSGAQKAETAANR 281
                  L  EDIV   +P  K ++T  +         H  +   +  TAAN+
Sbjct: 415 IGAGVYAL-PEDIVEV-KP--KMLLTVFACLMMRDLSAHKATQGVRGPTAANK 561
>38338
          Length = 463

 Score = 38.1 bits (87), Expect = 0.016,   Method: Compositional matrix adjust.
 Identities = 21/70 (30%), Positives = 39/70 (55%)
 Frame = -2

Query: 760 AKGISQEQMQEFRASFNHFDKDHGGALGPEEFKACLISLGYDVENDRQGDAEFNRIMSVV 819
           A  +++EQ+ EF+ +F+ FDKD  G +  +E    + SLG +       +AE   +++ V
Sbjct: 195 ADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPT-----EAELQDMINEV 31

Query: 820 DPNHSGLVTF 829
           D + +G + F
Sbjct: 30  DADGNGTIDF 1
>38533
          Length = 380

 Score = 37.7 bits (86), Expect = 0.021,   Method: Compositional matrix adjust.
 Identities = 14/50 (28%), Positives = 34/50 (68%)
 Frame = +1

Query: 446 TLSDIKALIRKHEAFESDLAAHQDRVEQIAAIAQELNELDYYDSHNVNTR 495
           +L+ ++ L++KH+A ES++ AH+  ++ +A  AQ++    ++ + ++ TR
Sbjct: 70  SLTAVQNLMKKHQALESEIVAHEPLIDAVATSAQQMIRTKHFATADIQTR 219
>20251
          Length = 2203

 Score = 37.4 bits (85), Expect = 0.025,   Method: Compositional matrix adjust.
 Identities = 29/110 (26%), Positives = 49/110 (44%)
 Frame = +3

Query: 763 ISQEQMQEFRASFNHFDKDHGGALGPEEFKACLISLGYDVENDRQGDAEFNRIMSVVDPN 822
             Q Q+QEF+ +FN  D++  G +  E+    L SLG   +N  +G  + + +M+     
Sbjct: 141 FDQSQIQEFKEAFNMIDQNRDGFIDKEDLGDMLASLG---KNPTEG--QLDEMMNXA--- 296

Query: 823 HSGLVTFQAFIDFMSRETTDTDTADQVIASFKVLAGDKNFITAEELRREL 872
             G + F  F+     +   TD  D +  +F     D   +  E+  REL
Sbjct: 297 -PGPINFTMFLTMFGDKLNGTDPEDVIKNAFACFDEDGKGVIQEDRLREL 443
>03732
          Length = 1114

 Score = 32.3 bits (72), Expect = 0.92,   Method: Compositional matrix adjust.
 Identities = 25/89 (28%), Positives = 35/89 (39%), Gaps = 10/89 (11%)
 Frame = -1

Query: 755 ILTRDAKGISQEQMQEFRA----------SFNHFDKDHGGALGPEEFKACLISLGYDVEN 804
           +  RD  G      QEF+A           F  +D+D+ G++   E K  L   GY    
Sbjct: 967 MFDRDNSGTIN--FQEFQALWKYVTDWQNCFRSYDRDNSGSIDRNELKNALTGFGY---- 806

Query: 805 DRQGDAEFNRIMSVVDPNHSGLVTFQAFI 833
            R  D  F+ ++   D    G V F  FI
Sbjct: 805 -RLSDRFFDVLVKKFDRQGKGTVAFDDFI 722
>22703
          Length = 906

 Score = 30.8 bits (68), Expect = 2.5,   Method: Compositional matrix adjust.
 Identities = 26/97 (26%), Positives = 49/97 (50%), Gaps = 9/97 (9%)
 Frame = -3

Query: 384 INNG---WQHLEQAEKGYEEWLLNEIRRLERLDHL------AEKFRQKASIHEAWTDGKE 434
           I NG    + +E+  K  ++ L   IR LE    L      A++ R +    EAW + +E
Sbjct: 847 IANGHFLSKEIEEKIKQLDQSLEGLIRNLEHRRKLHQQNLEAQQLRHEMEQIEAWMNLRE 668

Query: 435 AMLKQRDYETATLSDIKALIRKHEAFESDLAAHQDRV 471
            +LK++ +   ++   + ++R+H+ F   + A +DRV
Sbjct: 667 PLLKEKKF-GESIEGAEEMLRRHD*F*KTVTAQEDRV 560
>02929
          Length = 1353

 Score = 29.6 bits (65), Expect = 5.4,   Method: Compositional matrix adjust.
 Identities = 23/90 (25%), Positives = 40/90 (44%), Gaps = 6/90 (6%)
 Frame = +2

Query: 767 QMQEFRAS--FNHFDKDHGGALGPEEFKACLISLGYDVENDRQGDAEFNRIMSVVDPNHS 824
           Q ++FR +  F   DKD  G L  EEF   ++   +          E N +  + D    
Sbjct: 164 QAKKFRVTDFFRRQDKDGDGFLTEEEFVNGMMQSRFPTNR-----TELNAVFDIFDREKR 328

Query: 825 GLVTFQAFIDFMS----RETTDTDTADQVI 850
           GL+ ++ F+D +     R ++   + D+VI
Sbjct: 329 GLIEYKDFVDALKPDKFRTSSRAMSDDEVI 418
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|33859753|ref|NP_077777.1| RAS related protein 1b [Mus
musculus]
         (184 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

07580                                                                 273   5e-76
00858                                                                 151   2e-37
06994                                                                 117   8e-32
19046                                                                  93   5e-20
24619                                                                  90   5e-19
26536                                                                  86   1e-17
08428                                                                  79   8e-16
34468                                                                  77   3e-15
36482                                                                  77   4e-15
07465                                                                  76   7e-15
11257                                                                  73   7e-14
33374                                                                  72   2e-13
33380                                                                  69   8e-13
18509                                                                  61   1e-11
01972                                                                  64   3e-11
05468                                                                  60   4e-10
34597                                                                  59   8e-10
01398                                                                  59   1e-09
19006                                                                  57   3e-09
11728                                                                  57   6e-09
01095                                                                  56   1e-08
34359                                                                  55   1e-08
12339                                                                  55   2e-08
13745                                                                  55   2e-08
29380                                                                  53   8e-08
32723                                                                  49   1e-06
31928                                                                  47   3e-06
19656                                                                  47   4e-06
14119                                                                  42   2e-04
25618                                                                  41   3e-04
10708                                                                  41   4e-04
22152                                                                  27   5.2  
>07580
          Length = 921

 Score =  273 bits (698), Expect(2) = 5e-76,   Method: Compositional matrix adjust.
 Identities = 134/164 (81%), Positives = 146/164 (89%), Gaps = 2/164 (1%)
 Frame = +3

Query: 23  FVQGIFVEKYDPTIEDSYRKQVEVDAQQCMLEILDTAGTEQFTAMRDLYMKNGQGFALVY 82
             +GIFVEKYDPTIEDSYRKQVEVD QQCMLEILDTAGTEQFTAMRDLYMKNGQGF L Y
Sbjct: 120 LCKGIFVEKYDPTIEDSYRKQVEVDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFLLAY 299

Query: 83  SITAQSTFNDLQDLREQILRVKDTDDVPMILVGNKCDLEDERVVGKEQGQNLARQWNNCA 142
           SITAQSTFNDLQ+LREQILRVKDTDDVPM+LVGNKCDLEDERVVGK+QGQ LAR + +CA
Sbjct: 300 SITAQSTFNDLQELREQILRVKDTDDVPMLLVGNKCDLEDERVVGKDQGQGLARSF-SCA 476

Query: 143 FLESSAKSKINVNEIFYDLVRQINRKTPVPGKARKKS--SCQLL 184
           FLE+SAK++INVNEIF DLVRQIN+K+P     R KS  SC +L
Sbjct: 477 FLETSAKARINVNEIFMDLVRQINKKSPEQSGKRTKSKKSCTVL 608

 Score = 28.1 bits (61), Expect(2) = 5e-76,   Method: Compositional matrix adjust.
 Identities = 15/31 (48%), Positives = 15/31 (48%)
 Frame = +2

Query: 1  MREYXXXXXXXXXXXXXALTVQFVQGIFVEK 31
          MREY             ALTVQFVQG F  K
Sbjct: 53 MREYKLVVLGSGGVGKSALTVQFVQGDFCGK 145
>00858
          Length = 1658

 Score =  151 bits (381), Expect = 2e-37,   Method: Compositional matrix adjust.
 Identities = 78/165 (47%), Positives = 109/165 (66%)
 Frame = -2

Query: 1    MREYXXXXXXXXXXXXXALTVQFVQGIFVEKYDPTIEDSYRKQVEVDAQQCMLEILDTAG 60
            M EY             ALT+Q  Q  FVE+YDPT EDS RKQV +D + C+L+ILDTAG
Sbjct: 1597 MTEYKLVVVGAGGVGKSALTIQLXQNHFVEEYDPTXEDSXRKQVVIDGETCLLDILDTAG 1418

Query: 61   TEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTDDVPMILVGNKCDL 120
             E+ +AMRD  M+ G+GF  V+++    +F D+   REQI RVKD D+VPM+LVGNK DL
Sbjct: 1417 QEEXSAMRDQCMRTGEGFLCVFAVXNLKSFEDINQYREQIKRVKDADEVPMVLVGNKVDL 1238

Query: 121  EDERVVGKEQGQNLARQWNNCAFLESSAKSKINVNEIFYDLVRQI 165
               R V + QG+++A  + +  ++E+SAK++  V++ FY LVR+I
Sbjct: 1237 PI-RNVEQRQGKHMAELY-HIPYVETSAKTRQGVDDAFYTLVREI 1109
>06994
          Length = 429

 Score =  117 bits (294), Expect(2) = 8e-32,   Method: Compositional matrix adjust.
 Identities = 62/103 (60%), Positives = 65/103 (63%), Gaps = 32/103 (31%)
 Frame = +1

Query: 25  QGIFVEKYDPTIEDSYRKQVEVDAQQCMLEILDTAGT----------------------- 61
           +G   +KYDPTIEDSYRKQVEVD QQCMLEILDTAGT                       
Sbjct: 121 KGFLWKKYDPTIEDSYRKQVEVDGQQCMLEILDTAGTVHASHSNACVHGSLHAFVGTVTP 300

Query: 62  ---------EQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQD 95
                    EQFTAMRDLYMKNGQGF L YSITAQSTFNDLQ+
Sbjct: 301 LGRDALLNTEQFTAMRDLYMKNGQGFLLAYSITAQSTFNDLQE 429

 Score = 35.8 bits (81), Expect(2) = 8e-32,   Method: Compositional matrix adjust.
 Identities = 18/31 (58%), Positives = 18/31 (58%)
 Frame = +3

Query: 1  MREYXXXXXXXXXXXXXALTVQFVQGIFVEK 31
          MREY             ALTVQFVQGIFVEK
Sbjct: 48 MREYKLVVLGSGGVGKSALTVQFVQGIFVEK 140
>19046
          Length = 445

 Score = 93.2 bits (230), Expect = 5e-20,   Method: Compositional matrix adjust.
 Identities = 53/129 (41%), Positives = 77/129 (59%), Gaps = 6/129 (4%)
 Frame = -2

Query: 62  EQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTDDVPMILVGNKCDLE 121
           E+F+AMR+ YM+ G GF LV+S+T   +F ++ +   QILRVKD D  PMIL  NK DL 
Sbjct: 441 EEFSAMREQYMRKGDGFLLVFSVTDFRSFENMANFHTQILRVKDRDSYPMILCANKVDLV 262

Query: 122 DERVVGKEQGQNLARQWNNCAFLESSAK-SKINVNEIFYDLVRQINRKTPVPGKAR---- 176
            +R V +EQ ++LA +     ++E+SAK   +NV+  F+ +VR I  + P     R    
Sbjct: 261 HQRKVSEEQVRDLATRL-RIPYIETSAKDPPLNVDLAFHQVVRVIRAQPPHLKNQRHKHV 85

Query: 177 -KKSSCQLL 184
            KK  C +L
Sbjct: 84  GKKRKCAIL 58
>24619
          Length = 509

 Score = 90.1 bits (222), Expect = 5e-19,   Method: Compositional matrix adjust.
 Identities = 47/110 (42%), Positives = 70/110 (63%), Gaps = 1/110 (0%)
 Frame = -2

Query: 62  EQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTDDVPMILVGNKCDLE 121
           E+F+AMR+ YM+ G GF LV+S+    +F ++ +   QILRVKD D  PMIL  NK DL 
Sbjct: 505 EEFSAMREQYMRKGDGFLLVFSVIDYQSFENMVNFHTQILRVKDRDTYPMILCANKVDLV 326

Query: 122 DERVVGKEQGQNLARQWNNCAFLESSAK-SKINVNEIFYDLVRQINRKTP 170
            +R V +EQ ++LA +     ++E+SAK   +NV+  F+ +VR I  + P
Sbjct: 325 HQRKVSEEQVRDLATRL-RIPYIETSAKDPPLNVDLAFHQVVRVIRAQPP 179
>26536
          Length = 829

 Score = 85.5 bits (210), Expect = 1e-17,   Method: Compositional matrix adjust.
 Identities = 41/113 (36%), Positives = 72/113 (63%)
 Frame = +2

Query: 55  ILDTAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTDDVPMILV 114
            LDTAG E++++MR+ Y ++G GF +VYS+T  ++F + + +   + R +D   +  +L 
Sbjct: 140 FLDTAGQEEYSSMREHYTRSGDGFIVVYSVTDVTSFQEAEAVFRWLTRFQDETSIHAVLC 319

Query: 115 GNKCDLEDERVVGKEQGQNLARQWNNCAFLESSAKSKINVNEIFYDLVRQINR 167
           GNK DL  +R V  E+G+ +A +     F E+SAK+  NV+++++ L+R I R
Sbjct: 320 GNKTDLTSDRKVTPEEGRKMADRLGMLYF-ETSAKTGDNVSQVYHGLLRSIPR 475

 Score = 45.4 bits (106), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 18/32 (56%), Positives = 25/32 (78%)
 Frame = +2

Query: 18  ALTVQFVQGIFVEKYDPTIEDSYRKQVEVDAQ 49
           +LT++F Q  F++ YDPTIEDSYRK ++V  Q
Sbjct: 530 SLTIRFTQDTFLDVYDPTIEDSYRKMIQVSGQ 625
>08428
          Length = 1109

 Score = 79.3 bits (194), Expect = 8e-16,   Method: Compositional matrix adjust.
 Identities = 47/149 (31%), Positives = 80/149 (53%), Gaps = 1/149 (0%)
 Frame = -3

Query: 18   ALTVQFVQGIFVEKYDPTIEDSY-RKQVEVDAQQCMLEILDTAGTEQFTAMRDLYMKNGQ 76
            ++ ++FV G +    + TI  S+  K + VD      +I DTAG E+F A+  +Y +   
Sbjct: 1026 SIVLRFVTGSYRPSQESTIGASFMSKSLVVDGAGYRFQIWDTAGQEKFRALAPMYYRGAA 847

Query: 77   GFALVYSITAQSTFNDLQDLREQILRVKDTDDVPMILVGNKCDLEDERVVGKEQGQNLAR 136
               +VY +T   TF  ++   ++ LR     ++ + + GNKCDLE+ R V ++  Q  A 
Sbjct: 846  AAVIVYDVTRPRTFKSVKSWIQE-LRSFGPPNIVLAIAGNKCDLEELREVVEKDAQEYAS 670

Query: 137  QWNNCAFLESSAKSKINVNEIFYDLVRQI 165
               +  F E+SA + +NV E+F +L RQ+
Sbjct: 669  SI-SAIFGETSAMTAVNVEEMFTELARQL 586
>34468
          Length = 1502

 Score = 77.4 bits (189), Expect = 3e-15,   Method: Compositional matrix adjust.
 Identities = 53/158 (33%), Positives = 81/158 (51%), Gaps = 5/158 (3%)
 Frame = +1

Query: 19  LTVQFVQGIFVEKYDPTIEDSYR-KQVEVDAQQCMLEILDTAGTEQF-TAMRDLYMKNGQ 76
           LT +F  G F +K + TI   +R K ++VD++   L++ DTAG E+F  +M   Y +N  
Sbjct: 541 LTYRFCLGKFPDKTEATIGVDFREKSIQVDSEHLKLQLWDTAGQERFRKSMVQHYYRNVH 720

Query: 77  GFALVYSITAQSTFNDLQDLREQILRVKDTDDVPMILVGNKCDLEDERVVGKEQGQNLAR 136
               VY +T  S+F ++    E+  R   T  +P ILVGNKCD+ +   V     Q  A 
Sbjct: 721 AVVFVYDMTKMSSFENMPAWIEECDRHNLTKYIPRILVGNKCDVVERIAVNTNLAQKFA- 897

Query: 137 QWNNCAFLESSAK--SKIN-VNEIFYDLVRQINRKTPV 171
             +N    E+SAK   K N V+ IF  +  ++    P+
Sbjct: 898 DAHNMPLFETSAKDDEKANHVDAIFMTVAHKLKXSKPM 1011
>36482
          Length = 686

 Score = 77.0 bits (188), Expect = 4e-15,   Method: Compositional matrix adjust.
 Identities = 50/166 (30%), Positives = 86/166 (51%), Gaps = 4/166 (2%)
 Frame = +2

Query: 19  LTVQFVQGIFVEKYDPTIEDSYRKQVEVDAQQCMLEILDTAGTEQFTAMRDLYMKNGQGF 78
           LTV+F+   F+ +Y PT+E  Y+    ++     LEILDTAG   +   ++ Y      F
Sbjct: 2   LTVRFLTRRFIGEYCPTLESVYKYHTVIEDDDVRLEILDTAGQGTY-PWKEGYALWADCF 178

Query: 79  ALVYSITAQSTFNDLQDLREQILRVKDTDDVPMILVGNKCDLEDERVVGKEQGQNLARQW 138
             VYSI  + ++ +L  ++ Q+  V+ +  +  +L  NK DL  +R V +++G++LA + 
Sbjct: 179 VFVYSINDRQSYEELVQVKRQVESVRKSTSLTAVLAANKTDLLHDRQVTQKEGEDLAEE- 355

Query: 139 NNCAFLESSAKSKIN---VNEIFYDLVRQINR-KTPVPGKARKKSS 180
             C   E SA        +  +F+DL R+  + K    G+ RK S+
Sbjct: 356 IGCRLYEVSASEGSQMEAITSMFHDLYREFRKHKQQREGRQRKTSN 493
>07465
          Length = 1103

 Score = 76.3 bits (186), Expect = 7e-15,   Method: Compositional matrix adjust.
 Identities = 44/142 (30%), Positives = 78/142 (54%), Gaps = 1/142 (0%)
 Frame = +3

Query: 18  ALTVQFVQGIFVEKYDPTIE-DSYRKQVEVDAQQCMLEILDTAGTEQFTAMRDLYMKNGQ 76
           ++  ++ +GIF + Y  TI  D   +Q+EV  +   L + DTAG E+F A+   Y +  Q
Sbjct: 243 SMIQRYCKGIFTKDYKKTIGVDFLERQIEVGGEDVRLMLWDTAGQEEFDAITKAYYRGAQ 422

Query: 77  GFALVYSITAQSTFNDLQDLREQILRVKDTDDVPMILVGNKCDLEDERVVGKEQGQNLAR 136
              L +S   + +F  L+  + ++    +  ++ M++V NK DL D+ VV  E+ +NLA+
Sbjct: 423 ACVLAFSTVDRDSFEALETWKRKV--EDEVGEIGMVIVQNKIDLIDDAVVRPEEAENLAK 596

Query: 137 QWNNCAFLESSAKSKINVNEIF 158
           +     F  +S K  +NV+E+F
Sbjct: 597 KL-RLRFYRTSVKENMNVDEVF 659
>11257
          Length = 1102

 Score = 72.8 bits (177), Expect = 7e-14,   Method: Compositional matrix adjust.
 Identities = 38/128 (29%), Positives = 67/128 (52%), Gaps = 3/128 (2%)
 Frame = -2

Query: 41   RKQVEVDAQQCMLEILDTAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQI 100
             K V VD +   ++I DTAG E++ ++R  + +      L +S+    +   L D  ++ 
Sbjct: 1056 HKDVVVDGETFTMQIWDTAGQERYKSLRTPFYRGTDCCLLTFSVDNLKSLQSLSDWYDEF 877

Query: 101  LR---VKDTDDVPMILVGNKCDLEDERVVGKEQGQNLARQWNNCAFLESSAKSKINVNEI 157
            +    ++D+   P +++GNK D+E ER V  E   N  R   N  + E+SAK  +NV + 
Sbjct: 876  VNYADIQDSASFPFVIIGNKADIE-EREVSSEDAYNWCRTHGNLPYFETSAKDSLNVQQA 700

Query: 158  FYDLVRQI 165
            F  +VR++
Sbjct: 699  FLAVVRRL 676
>33374
          Length = 489

 Score = 71.6 bits (174), Expect = 2e-13,   Method: Compositional matrix adjust.
 Identities = 39/112 (34%), Positives = 67/112 (59%)
 Frame = +1

Query: 46  VDAQQCMLEILDTAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKD 105
           +D      EI DTAG E++ ++  +Y +  Q   +VY IT Q TF   +   +++ R + 
Sbjct: 160 LDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNQDTFGRAKTWVKELQR-QA 336

Query: 106 TDDVPMILVGNKCDLEDERVVGKEQGQNLARQWNNCAFLESSAKSKINVNEI 157
           + ++ + L GNK DL ++R+V  E+ Q  A + N+  F+E+SAK+ +NVN+I
Sbjct: 337 SPNIVIALAGNKADLANKRMVEFEEAQAYAEE-NSLLFMETSAKTAMNVNDI 489
>33380
          Length = 282

 Score = 69.3 bits (168), Expect = 8e-13,   Method: Compositional matrix adjust.
 Identities = 33/73 (45%), Positives = 47/73 (64%)
 Frame = +3

Query: 53  LEILDTAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTDDVPMI 112
           L+I DTAG E++  +   Y +   GF L+Y +T + +FN +QD   QI +    D+  ++
Sbjct: 66  LQIWDTAGQERYRTITTAYYRGAMGFILMYDVTNEESFNAVQDWCTQI-KTYSWDNAQVV 242

Query: 113 LVGNKCDLEDERV 125
           LVGNKCDLEDERV
Sbjct: 243 LVGNKCDLEDERV 281
>18509
          Length = 625

 Score = 61.2 bits (147), Expect(2) = 1e-11,   Method: Compositional matrix adjust.
 Identities = 31/66 (46%), Positives = 48/66 (72%)
 Frame = -3

Query: 102 RVKDTDDVPMILVGNKCDLEDERVVGKEQGQNLARQWNNCAFLESSAKSKINVNEIFYDL 161
           RVKD D+VPM+LVGNK DL   R V + QG+++A  + +  ++E+SAK++  V++ FY L
Sbjct: 548 RVKDADEVPMVLVGNKVDLPI-RNVEQRQGKHMAELY-HIPYVETSAKTRQGVDDAFYTL 375

Query: 162 VRQINR 167
           VR+I +
Sbjct: 374 VREIRK 357

 Score = 24.3 bits (51), Expect(2) = 1e-11,   Method: Compositional matrix adjust.
 Identities = 9/25 (36%), Positives = 15/25 (60%)
 Frame = -1

Query: 76  QGFALVYSITAQSTFNDLQDLREQI 100
           +GF  V+++    +F D+   REQI
Sbjct: 625 EGFLCVFAVNNLKSFEDINQYREQI 551
>01972
          Length = 2359

 Score = 63.9 bits (154), Expect = 3e-11,   Method: Compositional matrix adjust.
 Identities = 34/113 (30%), Positives = 64/113 (56%)
 Frame = +3

Query: 53  LEILDTAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTDDVPMI 112
             + DTAG E+F  +RD Y   GQ   +++ +T++ T+ ++ +    ++RV   +++P++
Sbjct: 453 FNVWDTAGQEKFGGLRDGYYIQGQCAVIMFDVTSRVTYKNVPNWHRDLVRV--CENIPIV 626

Query: 113 LVGNKCDLEDERVVGKEQGQNLARQWNNCAFLESSAKSKINVNEIFYDLVRQI 165
           L GNK D++D +V  K +     R+  N  + + SAKS  N  + F  L R++
Sbjct: 627 LCGNKVDIKDRKV--KAKAIVFHRK-KNLQYYDISAKSNYNFEKPFLWLARKL 776
>05468
          Length = 1558

 Score = 60.5 bits (145), Expect = 4e-10,   Method: Compositional matrix adjust.
 Identities = 46/153 (30%), Positives = 74/153 (48%), Gaps = 6/153 (3%)
 Frame = -3

Query: 22   QFVQGIFVEKYDPTIE-DSYRKQVEVDAQQCM-LEILDTAGTEQFTAMRDLYMKNGQGFA 79
            ++V   F + Y  TI  D   K +  DA   + L++ D AG E+F  M  +Y K   G  
Sbjct: 1484 RYVHQFFSQHYRATIGVDFALKVLNWDADTLIRLQLWDIAGQERFGNMTRVYYKEAVGAF 1305

Query: 80   LVYSITAQSTFNDLQDLREQI---LRVKDTDDVPMILVGNKCDLEDERVVGK-EQGQNLA 135
            +V+ +T  STF+ +   +  +   +++ D   VP +L+ NKCD   E +V    Q     
Sbjct: 1304 VVFDVTRASTFDAVTKWKNDLDSKVQLADGSPVPCVLLANKCDQAKEGLVNNTSQMDEFC 1125

Query: 136  RQWNNCAFLESSAKSKINVNEIFYDLVRQINRK 168
             +     + E+SAK  IN++E    LV +I  K
Sbjct: 1124 SEKGFIGWYETSAKENINIDEAARFLVTRILEK 1026
>34597
          Length = 773

 Score = 59.3 bits (142), Expect = 8e-10,   Method: Compositional matrix adjust.
 Identities = 29/63 (46%), Positives = 45/63 (71%)
 Frame = -2

Query: 107 DDVPMILVGNKCDLEDERVVGKEQGQNLARQWNNCAFLESSAKSKINVNEIFYDLVRQIN 166
           +DV  +++GNKCD+ D+RVV KE+G+ +AR+ ++  F+E+SAKS IN+   F +L   I 
Sbjct: 658 EDVEKMILGNKCDMTDKRVVSKERGEAIARE-HSIRFMETSAKSNINIERAFCELAEAIL 482

Query: 167 RKT 169
            KT
Sbjct: 481 DKT 473
>01398
          Length = 1421

 Score = 58.5 bits (140), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 31/102 (30%), Positives = 55/102 (53%)
 Frame = -2

Query: 62   EQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTDDVPMILVGNKCDLE 121
            E+F ++   Y +N  G  +VY IT +STF +L+   E+     +      +++G+K D E
Sbjct: 1417 ERFRSITRSYYRNSVGVIIVYDITKRSTFENLKQWYEEARNHIEPHKAIFLVLGHKSDRE 1238

Query: 122  DERVVGKEQGQNLARQWNNCAFLESSAKSKINVNEIFYDLVR 163
            D R V   +G+  A + +   F E+SAKS  N+ ++F  + +
Sbjct: 1237 DARQVTAREGRRFA-EMHGLKFFETSAKSGHNIEDVFAQIAK 1115
>19006
          Length = 568

 Score = 57.4 bits (137), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 34/112 (30%), Positives = 59/112 (52%)
 Frame = -2

Query: 18  ALTVQFVQGIFVEKYDPTIEDSYRKQVEVDAQQCMLEILDTAGTEQFTAMRDLYMKNGQG 77
            L + F +  F E Y PT+ ++Y   +EVD++Q  L + DTAG E +  +R L   +   
Sbjct: 393 CLLIVFSKDQFPEVYVPTVFENYVADIEVDSKQVELALWDTAGQEDYDRLRPLSYPDTDV 214

Query: 78  FALVYSITAQSTFNDLQDLREQILRVKDTDDVPMILVGNKCDLEDERVVGKE 129
             + +SI +  +  ++ +     +R     +VP+ILVGNK DL ++    +E
Sbjct: 213 ILMCFSIDSPDSLENIPEKWTPEVR-HFCPNVPIILVGNKKDLRNDENTKRE 61
>11728
          Length = 635

 Score = 56.6 bits (135), Expect = 6e-09,   Method: Compositional matrix adjust.
 Identities = 39/142 (27%), Positives = 66/142 (46%), Gaps = 12/142 (8%)
 Frame = -1

Query: 19  LTVQFVQGIFVEKYDPTIEDSYRKQVEVDAQQCMLEILDTAGTEQFTAMRDLYMKNGQGF 78
           L + +    F  +Y PT+ D+Y   V VD++   L + DTAG E +  +R L       F
Sbjct: 443 LLISYTTNAFPGEYIPTVFDNYSANVMVDSKPINLGLWDTAGQEDYDRLRPLSYPQTDVF 264

Query: 79  ALVYSITAQSTFNDLQDLREQILRVKDTDDVPMILVGNKCDL-EDERVVGK--------- 128
            + +S+ + ++F +++      +      + P+ILVG K DL ED+  + K         
Sbjct: 263 LICFSLISPASFENVKAKWYPEVS-HHCPNTPIILVGTKLDLREDKETIEKLKEKKLAPI 87

Query: 129 --EQGQNLARQWNNCAFLESSA 148
              QG  +A+      +LE SA
Sbjct: 86  TYPQGLAMAKDIGAGKYLECSA 21
>01095
          Length = 1745

 Score = 55.8 bits (133), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 32/104 (30%), Positives = 61/104 (58%)
 Frame = -1

Query: 80   LVYSITAQSTFNDLQDLREQILRVKDTDDVPMILVGNKCDLEDERVVGKEQGQNLARQWN 139
            +VY IT Q TF   +   +++ R + + ++ + L GNK DL ++R+V  E+ Q  A + N
Sbjct: 1745 VVYDITNQDTFGRAKTWVKELQR-QASPNIVIALAGNKADLANKRMVEFEEAQAYAEE-N 1572

Query: 140  NCAFLESSAKSKINVNEIFYDLVRQINRKTPVPGKARKKSSCQL 183
            +  F+E+SAK+ +NVN+IF  + +++ +     G   ++   +L
Sbjct: 1571 SLLFMETSAKTAMNVNDIFLAIAKKLPKNEGGGGSQPRQQGVRL 1440
>34359
          Length = 1042

 Score = 55.1 bits (131), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 23/77 (29%), Positives = 46/77 (59%)
 Frame = +3

Query: 53  LEILDTAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTDDVPMI 112
             + DTAG E+F  +RD Y   G    +++ +T++ T+ ++ +    ++RV   +++P++
Sbjct: 201 FNVWDTAGQEKFGGLRDGYYIQGTCAIIMFDVTSRVTYKNVPNWHRDLVRV--CENIPIV 374

Query: 113 LVGNKCDLEDERVVGKE 129
           L GNK D++D +V  K 
Sbjct: 375 LCGNKVDIKDRKVKAKA 425
>12339
          Length = 578

 Score = 55.1 bits (131), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 31/100 (31%), Positives = 50/100 (50%), Gaps = 3/100 (3%)
 Frame = -2

Query: 62  EQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILR---VKDTDDVPMILVGNKC 118
           E+F ++   + +      LVY +T   TF+ L   + + L     +D +  P +++GNK 
Sbjct: 574 ERFQSLGVAFYRGADCCILVYDVTEXKTFDSLDSWQREFLNQASPRDPEHFPFVVIGNKI 395

Query: 119 DLEDERVVGKEQGQNLARQWNNCAFLESSAKSKINVNEIF 158
           DL D RVV  ++GQ          + E+SAK  INV + F
Sbjct: 394 DL-DNRVVTAKRGQGWCSTKGGIPYFETSAKEAINVEQAF 278
>13745
          Length = 1045

 Score = 55.1 bits (131), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 31/105 (29%), Positives = 54/105 (51%), Gaps = 3/105 (2%)
 Frame = +2

Query: 62  EQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQIL---RVKDTDDVPMILVGNKC 118
           E+F ++   + +      LVY +TA ++F +L   R++ L     +D +  P +++GNK 
Sbjct: 5   ERFQSLGVAFYRGADCCVLVYDVTAPNSFKNLDSWRDEFLIQASPRDPEHFPFVVLGNKV 184

Query: 119 DLEDERVVGKEQGQNLARQWNNCAFLESSAKSKINVNEIFYDLVR 163
           DL D R V   + Q   +  N+  + E+SAK  INV   F  + +
Sbjct: 185 DL-DNRQVSTRRAQQWCQSKNDIPYYETSAKEGINVEMAFQTIAK 316
>29380
          Length = 853

 Score = 52.8 bits (125), Expect = 8e-08,   Method: Compositional matrix adjust.
 Identities = 36/88 (40%), Positives = 51/88 (57%), Gaps = 2/88 (2%)
 Frame = -2

Query: 80  LVYSITAQSTFN-DLQDLREQILRVKDTDDVPMILVGNKCDLEDE-RVVGKEQGQNLARQ 137
           +VY +    TF+  L  ++E  LR ++T+ V +IL GNK DL  + R V  E  Q+ AR+
Sbjct: 837 IVYDVNIADTFSRALAWVKE--LRQQNTESVLIILAGNKVDLATQHRAVSFEDAQSFARE 664

Query: 138 WNNCAFLESSAKSKINVNEIFYDLVRQI 165
            N   F E SAK+ + VNEIF  L  Q+
Sbjct: 663 -NGLLFAEVSAKTGMAVNEIFMTLANQL 583
>32723
          Length = 384

 Score = 48.5 bits (114), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 31/105 (29%), Positives = 51/105 (48%)
 Frame = +2

Query: 62  EQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTDDVPMILVGNKCDLE 121
           E+F ++   Y ++     LVY + +Q ++  L     +I     T  V   LVGNK D  
Sbjct: 5   ERFRSITQSYYRSANALILVYDVCSQQSYESLPQWIHEIELYAGTK-VLAFLVGNKIDQT 181

Query: 122 DERVVGKEQGQNLARQWNNCAFLESSAKSKINVNEIFYDLVRQIN 166
           D+R +    G+  A ++    FLE+SAK   NV ++F  +  Q+ 
Sbjct: 182 DKREIPTHIGKEFAERYE-MRFLETSAKEADNVEKLFSTIAYQLT 313
>31928
          Length = 429

 Score = 47.4 bits (111), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 31/87 (35%), Positives = 44/87 (50%), Gaps = 4/87 (4%)
 Frame = +2

Query: 35  TIEDSYRKQVEVD-AQQCMLEILDTAGTEQFTAMRDL---YMKNGQGFALVYSITAQSTF 90
           TIED Y   +E D   +  + I DT      T   DL   Y+    GF LVY  T+  +F
Sbjct: 53  TIEDIYTAVIETDRGVKEKVRIFDTGAAALETTEGDLPKHYLNFPDGFVLVYDTTSWESF 232

Query: 91  NDLQDLREQILRVKDTDDVPMILVGNK 117
             L  L++ I + +D  +V MI++GNK
Sbjct: 233 RRLDKLKKDIDKHRDKREVHMIVIGNK 313
>19656
          Length = 428

 Score = 47.4 bits (111), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 22/76 (28%), Positives = 39/76 (51%)
 Frame = +3

Query: 19  LTVQFVQGIFVEKYDPTIEDSYRKQVEVDAQQCMLEILDTAGTEQFTAMRDLYMKNGQGF 78
           L + +    F  +Y PT+ D+Y   V VD +   L + DTAG E +  +R L       F
Sbjct: 159 LLISYTTNAFPGEYIPTVFDNYSANVMVDGRPVNLGLWDTAGQEDYDRLRPLSYPQTDVF 338

Query: 79  ALVYSITAQSTFNDLQ 94
            L +S+ + ++F +++
Sbjct: 339 LLCFSVASPASFENIR 386
>14119
          Length = 602

 Score = 42.0 bits (97), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 24/74 (32%), Positives = 38/74 (51%), Gaps = 1/74 (1%)
 Frame = +1

Query: 101 LRVKDTDDVPMILVGNKCDLEDE-RVVGKEQGQNLARQWNNCAFLESSAKSKINVNEIFY 159
           LR ++   V ++L GNK DL  E R V  +  +  A   N   F E SAK+ + V+E+F 
Sbjct: 34  LRQQNAGSVLIVLAGNKADLASEHRAVSADDARTFAED-NGLIFAEVSAKTGMAVSEVFM 210

Query: 160 DLVRQINRKTPVPG 173
            +  ++ R+    G
Sbjct: 211 TIAHKLVRRAEEGG 252
>25618
          Length = 475

 Score = 40.8 bits (94), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 23/70 (32%), Positives = 37/70 (52%), Gaps = 1/70 (1%)
 Frame = +3

Query: 101 LRVKDTDDVPMILVGNKCDLEDE-RVVGKEQGQNLARQWNNCAFLESSAKSKINVNEIFY 159
           LR ++   V ++L GNK DL  E R V  +  +  A   N   F E SAK+ + V+E+F 
Sbjct: 54  LRQQNAGSVLIVLAGNKADLASEHRAVSADDARTFAED-NGLIFAEVSAKTGMAVSEVFM 230

Query: 160 DLVRQINRKT 169
            +  ++ R+ 
Sbjct: 231 TIAHKLVRRA 260
>10708
          Length = 2775

 Score = 40.8 bits (94), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 28/89 (31%), Positives = 45/89 (50%), Gaps = 12/89 (13%)
 Frame = -3

Query: 108  DVPMILVGNKCDLEDERVVGKE------------QGQNLARQWNNCAFLESSAKSKINVN 155
            +VP+ILVGNK DL ++    +E            +G+ ++ + N  ++LE SAK+K  V 
Sbjct: 2554 NVPIILVGNKKDLRNDENTKRELMKMKQEPVRLDEGRAMSEKINAYSYLECSAKTKEGVR 2375

Query: 156  EIFYDLVRQINRKTPVPGKARKKSSCQLL 184
            E+F    R       +  K +KK  C +L
Sbjct: 2374 EVFETATR-----AALQTKKKKKGGCIVL 2303
>22152
          Length = 610

 Score = 26.9 bits (58), Expect = 5.2,   Method: Compositional matrix adjust.
 Identities = 16/47 (34%), Positives = 26/47 (55%), Gaps = 1/47 (2%)
 Frame = +2

Query: 127 GKEQGQNLARQWNNCA-FLESSAKSKINVNEIFYDLVRQINRKTPVP 172
           G ++G++L+ Q    A  +E     K +VN + + L RQI   TP+P
Sbjct: 374 GSKRGESLSHQVGMFASIIEEMQMCKFDVNNL*FYLWRQIQF*TPLP 514
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6755847|ref|NP_035752.1| target of myb1 homolog
isoform 1 [Mus musculus]
         (492 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

30964                                                                 166   1e-75
30899                                                                  69   4e-12
14965                                                                  60   3e-09
21026                                                                  56   3e-08
07665                                                                  33   0.28 
20802                                                                  28   9.5  
>30964
          Length = 894

 Score =  166 bits (420), Expect(3) = 1e-75,   Method: Compositional matrix adjust.
 Identities = 79/132 (59%), Positives = 101/132 (76%), Gaps = 3/132 (2%)
 Frame = -1

Query: 43  TEEGPKDAFRAVKKRIMGN--KNFHEVMLALTVLETCVKNCGHRFHVLVANQDFVENVLV 100
           T+EGPKDA RA KKR+  N  KNF  +M  LT LETCVKNCG RFHV VA +DF++  LV
Sbjct: 864 TDEGPKDASRAFKKRLSQNVGKNFTAIMYTLTCLETCVKNCGRRFHVCVATKDFLQE-LV 688

Query: 101 RTILPKNNPPTIVHDKVLNLIQSWADAFRSSPDLTGVVAVYEDLRRKGLEFPMTDLDMLS 160
           + I PK++PP  V +KVL +IQ+WADAFR +P+L  V  +Y++L+ KG+EFPMTDLD ++
Sbjct: 687 KVIGPKHDPPQAVQEKVLQMIQTWADAFRGAPELKEVEKIYQELKSKGIEFPMTDLDNMA 508

Query: 161 PIHTPQRTV-FN 171
           PIHTP R+V FN
Sbjct: 507 PIHTPARSVPFN 472

 Score =  132 bits (332), Expect(3) = 1e-75,   Method: Compositional matrix adjust.
 Identities = 66/119 (55%), Positives = 90/119 (75%)
 Frame = -3

Query: 203 VLPGDSPITPTPEQIGKLRSELEMVSGNVRVMSEMLTELVPTQVEPADLELLQELNRTCR 262
           ++P + P T   +Q  KL  ELE+VSGNVRVM EMLTE+ P+  + +D+ELLQEL+RTCR
Sbjct: 373 IIPSE-PTTLNTDQRSKLSRELEVVSGNVRVMGEMLTEMSPSSPDASDMELLQELHRTCR 197

Query: 263 AMQQRILELIPRISNEQLTEELLMINDNLNNVFLRHERFERFRTGQTAKASSEAELATD 321
            MQQR+++L+  ++NE++T ELL +ND+LNNVFLR+ERFER+R+GQ A    E   A D
Sbjct: 196 QMQQRVMQLLGEVANEEVTGELLRVNDDLNNVFLRYERFERYRSGQGAPEIPEPTPAAD 20

 Score = 24.6 bits (52), Expect(3) = 1e-75,   Method: Compositional matrix adjust.
 Identities = 9/15 (60%), Positives = 12/15 (80%)
 Frame = -2

Query: 34  MEICDIINETEEGPK 48
           ME+CD+INE  + PK
Sbjct: 890 MEVCDMINEQTKDPK 846
>30899
          Length = 698

 Score = 68.9 bits (167), Expect = 4e-12,   Method: Compositional matrix adjust.
 Identities = 33/89 (37%), Positives = 53/89 (59%)
 Frame = -3

Query: 10  SSPVGQRIEKATDGSLQSEDWALNMEICDIINETEEGPKDAFRAVKKRIMGNKNFHEVML 69
           +SP    +EKAT     SEDW L ++IC+ +   + G +D  +++ KR+     F   M 
Sbjct: 675 TSPFDVDVEKATHEMSTSEDWGLILDICEKVGRQQNGARDCLKSIVKRLNHKVPF-VAMQ 499

Query: 70  ALTVLETCVKNCGHRFHVLVANQDFVENV 98
           ALT+L+ CV NCG +FH+ + ++D  +NV
Sbjct: 498 ALTLLDACVNNCGRQFHLEICSRDLPQNV 412
>14965
          Length = 949

 Score = 59.7 bits (143), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 50/144 (34%), Positives = 73/144 (50%), Gaps = 14/144 (9%)
 Frame = +2

Query: 363 EDDFDMFALTRGS-SLADQRKGVKYEAPQTTDGLAGALDARQQSTGAIPATQARIM---- 417
           ++DFDMFA +R S     Q  G  Y + Q  D L GAL    Q+  + P +   I+    
Sbjct: 2   DEDFDMFAQSRQSVEQTRQATGPIY-SNQREDQLTGAL---SQTAASKPQSDNDILNLQD 169

Query: 418 -----EDIEQWLSTD----VGNSAEEPSGVTSEEFDKFLEERAKAADRLPNLASPSAEGP 468
                +++EQWL+T       NS     G+TS EFD+FL ERA AA+ +P +  P+  G 
Sbjct: 170 KDTDYDEMEQWLATHDPNAAANSGARQEGLTSSEFDRFLLERAAAAENMPTI--PAQTG- 340

Query: 469 PRPSPGTAPRRKTQEKDDDMLFAL 492
             P      R+  ++++D  LFAL
Sbjct: 341 --PQSARNTRQMKRDEEDKSLFAL 406
>21026
          Length = 682

 Score = 56.2 bits (134), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 52/151 (34%), Positives = 76/151 (50%), Gaps = 21/151 (13%)
 Frame = -2

Query: 363 EDDFDMFALTRGSSLADQRK---GVKYE---APQTTDGLAGALDARQQSTGAIPATQAR- 415
           ++DFDMFA +R S   DQ K   G  Y      Q   GL  A+  + QS   +   Q + 
Sbjct: 681 DEDFDMFAQSRQS--FDQNKQTPGPVYSNQREDQMAAGLGQAVSIKSQSDQDVLGLQDKE 508

Query: 416 -IMEDIEQWLSTDVGNSA-------EEP------SGVTSEEFDKFLEERAKAADRLPNLA 461
              +++EQWL+T   N+A       EE        G+TS EFD FL +RA A   +P + 
Sbjct: 507 TDYDEMEQWLATHDPNAAAALRLYKEESEAGGRTEGLTSSEFDNFLSDRASATGGVPTI- 331

Query: 462 SPSAEGPPRPSPGTAPRRKTQEKDDDMLFAL 492
             SA+   +P+ G   R+  +E++D+ LFAL
Sbjct: 330 --SAQTGQQPAAGRNARQMKKEEEDNSLFAL 244
>07665
          Length = 435

 Score = 33.1 bits (74), Expect = 0.28,   Method: Composition-based stats.
 Identities = 22/67 (32%), Positives = 35/67 (52%), Gaps = 2/67 (2%)
 Frame = -3

Query: 160 SPIHTPQRT-VFNSETPSRQNSVSSNTSQRGDLSQHATPLPTPAVLPGDSPITP-TPEQI 217
           SP+  P R+ +++++ PSR  ++ S+   +   S  A P P P +    SP TP TP   
Sbjct: 298 SPMAHPSRSGIWHAKRPSRSCALRSSRPHQRPSSHSACPWPGPPMARPCSPATPTTPSAS 119

Query: 218 GKLRSEL 224
           GK   +L
Sbjct: 118 GKCLYQL 98
>20802
          Length = 526

 Score = 28.1 bits (61), Expect = 9.5,   Method: Compositional matrix adjust.
 Identities = 17/47 (36%), Positives = 29/47 (61%), Gaps = 2/47 (4%)
 Frame = +2

Query: 250 DLELLQELNRTCRAMQQRILE--LIPRISNEQLTEELLMINDNLNNV 294
           D+E ++ L++ CR ++   L+  LIP+I N    ++L  +N  LNNV
Sbjct: 215 DIERIEYLDKWCRELKILYLQSNLIPKIENVSRLKKLEYLNLALNNV 355
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|148528987|ref|NP_780693.2| coronin, actin binding
protein, 2B [Mus musculus]
         (480 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

16105                                                                 278   2e-75
30679                                                                 200   7e-64
03387                                                                  66   2e-11
01768                                                                  64   2e-10
01805                                                                  61   9e-10
12841                                                                  54   2e-07
12574                                                                  50   3e-06
00561                                                                  47   1e-05
19949                                                                  47   2e-05
01598                                                                  46   3e-05
12140                                                                  46   3e-05
01327                                                                  46   4e-05
15780                                                                  46   4e-05
10264                                                                  46   4e-05
18981                                                                  44   2e-04
17602                                                                  43   2e-04
07741                                                                  43   3e-04
19498                                                                  42   4e-04
30256                                                                  42   5e-04
03156                                                                  42   6e-04
31474                                                                  42   8e-04
13335                                                                  41   0.001
27475                                                                  40   0.001
02090                                                                  39   0.003
17598                                                                  39   0.004
27465                                                                  39   0.004
02960                                                                  38   0.010
27806                                                                  37   0.018
12806                                                                  36   0.027
37142                                                                  36   0.032
10162                                                                  35   0.054
01249                                                                  35   0.069
11493                                                                  34   0.12 
30108                                                                  34   0.16 
20662                                                                  33   0.23 
08355                                                                  32   0.46 
15745                                                                  31   1.1  
02948                                                                  31   1.4  
37180                                                                  30   1.7  
01462                                                                  30   2.5  
25400                                                                  30   2.7  
27562                                                                  29   3.5  
00825                                                                  29   4.3  
30176                                                                  29   4.6  
02828                                                                  28   6.7  
06078                                                                  28   6.7  
29912                                                                  28   8.0  
17266                                                                  28   8.1  
>16105
          Length = 960

 Score =  278 bits (712), Expect = 2e-75,   Method: Compositional matrix adjust.
 Identities = 132/267 (49%), Positives = 188/267 (70%), Gaps = 1/267 (0%)
 Frame = -2

Query: 13  RSSKFRNVYGKAANREHCFDGIPITKNVHDNHFCAVNARFLAIVTESAGGGSFLVIPLEQ 72
           R SKFR+V+GK   R+ C+DGI IT+   ++ +CAVN +F+A++TE+AGGG+FLV+PL +
Sbjct: 797 RQSKFRHVFGKPEKRDQCYDGIRITRTSWESTYCAVNPKFVAVMTEAAGGGAFLVLPLSR 618

Query: 73  TGRIEPNYPKVCGHQGNVLDIKWNPFIDNIIASCSEDTSVRIWEIPDGGLKRNMTEALLE 132
            GR+  + P V GH+G VLDI+W P  DN+IAS S+D +V++W+IPD GL  N+T+ +++
Sbjct: 617 VGRVPVDNPLVAGHKGAVLDIQWCPHNDNVIASASDDCTVKVWQIPDSGLVTNLTDPVVD 438

Query: 133 LHGHSRRVGLVEWHPTTNNILFSAGYDYKVLIWNLDIGEPVKMIDCHTDVILCMSFNTDG 192
           L GH +R  L+ WHP+  N+L SAG D K+L WN+  GEP+  +D   D+I CMSFN +G
Sbjct: 437 LVGHQKRCCLIVWHPSAQNVLVSAGADNKILFWNVGTGEPMLEVDV-PDMIYCMSFNFNG 261

Query: 193 SLLTTTCKDKKLRVIEPRSGRVLQEANCKN-HRVNRVVFLGNMKRLLTTGVSRWNTRQIA 251
           S L  TCKDKKLR+I+  SG VL+E  C +  +  +  +L + K + TTG SR + RQ A
Sbjct: 260 SRLVCTCKDKKLRIIDSHSGAVLKEGKCHDGAKPAQACYLKDGK-VFTTGFSRMSERQYA 84

Query: 252 LWDQEDLSMPMIEEEIDGLSGLLFPFY 278
           +WD+ DLS  M  EEID  +G++F FY
Sbjct: 83  IWDENDLSESMTLEEIDSSNGVMFIFY 3
>30679
          Length = 1025

 Score =  200 bits (509), Expect(3) = 7e-64,   Method: Compositional matrix adjust.
 Identities = 90/191 (47%), Positives = 130/191 (68%), Gaps = 1/191 (0%)
 Frame = +1

Query: 151 NILFSAGYDYKVLIWNLDIGEPVKMIDCHTDVILCMSFNTDGSLLTTTCKDKKLRVIEPR 210
           NIL SAG+DYK ++WN++  EPV ++DCHTD I  MS+N  GS+  TT KDKKLR I+PR
Sbjct: 1   NILLSAGFDYKCVVWNVEQAEPVNIVDCHTDTIFSMSWNRXGSMFATTSKDKKLRTIDPR 180

Query: 211 SGRVLQEANC-KNHRVNRVVFLGNMKRLLTTGVSRWNTRQIALWDQEDLSMPMIEEEIDG 269
           +  V  E+ C K  + ++VVF  N+K L TTG ++  +R+++LWD       +   ++D 
Sbjct: 181 TTTVAAESQCHKGPKASKVVFADNVK-LTTTGFAQMGSRELSLWDLRKSKTAIHTVDLDS 357

Query: 270 LSGLLFPFYDADTHMLYLAGKGDGNIRYYEISTEKPYLSYLMEFRSPAPQKGLGVMPKHG 329
             G++ P+YD DT +++LAGKGDGNIRY+E+S       +L  ++SP+PQ+GLG+MPK G
Sbjct: 358 SCGVMLPYYDYDTRVIFLAGKGDGNIRYFEVSDTDSCFHFLNAYQSPSPQRGLGMMPKRG 537

Query: 330 LDVSACEVFRF 340
            D   CE+ RF
Sbjct: 538 CDTKRCEIMRF 570

 Score = 42.0 bits (97), Expect(3) = 7e-64,   Method: Compositional matrix adjust.
 Identities = 17/27 (62%), Positives = 23/27 (85%)
 Frame = +2

Query: 342 KLVTLKGLIEPISMIVPRRSDSYQEDI 368
           +L   K L+EPISMIVPR+SD++QED+
Sbjct: 572 QLHAAKNLVEPISMIVPRKSDAFQEDV 652

 Score = 41.2 bits (95), Expect(3) = 7e-64,   Method: Compositional matrix adjust.
 Identities = 19/49 (38%), Positives = 30/49 (61%)
 Frame = +3

Query: 369 YPMTPGTEPALTPDEWLGGINRDPVLMSLKEGYKKSSKVVFKAPIREKK 417
           YP T  T P+L  DEW+ G NR+P+L+S+ +G   SS  +  +   +K+
Sbjct: 654 YPPTASTIPSLRADEWISGQNREPILVSMVDGTVVSSPQITTSKAVQKQ 800
>03387
          Length = 1891

 Score = 66.2 bits (160), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 49/200 (24%), Positives = 93/200 (46%), Gaps = 6/200 (3%)
 Frame = +1

Query: 82  KVCGHQGNVLDIKWNPFIDNIIASCSEDTSVRIWEIPDGGLKRNMTEALLELHGHSRRVG 141
           ++ GHQ     + WNP ++  + S S+D ++ +W+I     +  + +A     GH+  V 
Sbjct: 346 RLKGHQKEGYGLSWNPNLNGHLLSASDDHTICLWDINSTQRESRVVDAHTIFTGHTSVVE 525

Query: 142 LVEWHPTTNNILFSAGYDYKVLIWNL---DIGEPVKMIDCHTDVILCMSFNTDGS-LLTT 197
            V WH    ++  S   D K++IW+       +P  ++D HT  + C+SFN     +L T
Sbjct: 526 DVAWHLLHESLFGSVADDQKLMIWDTRSNTTSKPSHVVDAHTAEVNCLSFNPYSEFILAT 705

Query: 198 TCKDKKLRVIEPRSGRV-LQEANCKNHRVNRVVFLGNMKRLLTTGVSRWNTRQIALWDQE 256
              DK + + + R+ ++ L         + +V +  + + +L    S    R++ +WD  
Sbjct: 706 GSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPHNETIL---ASSGTDRRLHVWDLS 876

Query: 257 DLSMPMIEEEI-DGLSGLLF 275
            +    + E+  DG   LLF
Sbjct: 877 KIGEEQLPEDAEDGPPELLF 936

 Score = 47.8 bits (112), Expect = 9e-06,   Method: Compositional matrix adjust.
 Identities = 55/230 (23%), Positives = 100/230 (43%), Gaps = 16/230 (6%)
 Frame = +1

Query: 49  NARFLAIVTESAGG--GSFLVIPLEQTGRIEPNYPKVCGHQGNVLDIKWNPFIDNIIASC 106
           NA+F A   +S  G  G F  +    +G+IE        H+G V   ++ P    IIA+ 
Sbjct: 100 NAQFDAAQYDSEKGEFGGFGSV----SGKIEIEIK--INHEGEVNRARYMPQNPCIIATK 261

Query: 107 SEDTSVRIWEIPDGGLKRNMTEAL---LELHGHSRRVGLVEWHPTTNNILFSAGYDYKVL 163
           +  + V +++      K + +      L L GH +    + W+P  N  L SA  D+ + 
Sbjct: 262 TPSSDVLVFDYTKHPSKPDPSGECIPELRLKGHQKEGYGLSWNPNLNGHLLSASDDHTIC 441

Query: 164 IWNLDIGE-PVKMIDCHTDVILCMSFNTD-------GSLLTTTCKDKKLRVIEPRSGRVL 215
           +W+++  +   +++D HT      S   D        SL  +   D+KL + + RS    
Sbjct: 442 LWDINSTQRESRVVDAHTIFTGHTSVVEDVAWHLLHESLFGSVADDQKLMIWDTRSNTTS 621

Query: 216 QEA---NCKNHRVNRVVFLGNMKRLLTTGVSRWNTRQIALWDQEDLSMPM 262
           + +   +     VN + F    + +L TG +    + +ALWD  +L + +
Sbjct: 622 KPSHVVDAHTAEVNCLSFNPYSEFILATGSA---DKTVALWDLRNLKLKL 762

 Score = 39.3 bits (90), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 21/89 (23%), Positives = 44/89 (49%), Gaps = 7/89 (7%)
 Frame = +1

Query: 86  HQGNVLDIKWNPFIDNIIASCSEDTSVRIWEIPDGGLKRNMTEA------LLELHG-HSR 138
           H+  +  ++W+P  + I+AS   D  + +W++   G ++   +A      LL +HG H+ 
Sbjct: 778 HKDEIFQVQWSPHNETILASSGTDRRLHVWDLSKIGEEQLPEDAEDGPPELLFIHGGHTA 957

Query: 139 RVGLVEWHPTTNNILFSAGYDYKVLIWNL 167
           ++    W+P    I+ S   D  + +W +
Sbjct: 958 KISDFSWNPNEPWIVCSVSEDNIMQVWQM 1044

 Score = 32.0 bits (71), Expect = 0.54,   Method: Compositional matrix adjust.
 Identities = 12/35 (34%), Positives = 20/35 (57%)
 Frame = +1

Query: 85  GHQGNVLDIKWNPFIDNIIASCSEDTSVRIWEIPD 119
           GH   + D  WNP    I+ S SED  +++W++ +
Sbjct: 946 GHTAKISDFSWNPNEPWIVCSVSEDNIMQVWQMAE 1050
>01768
          Length = 1424

 Score = 63.5 bits (153), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 42/158 (26%), Positives = 74/158 (46%), Gaps = 6/158 (3%)
 Frame = +3

Query: 55  IVTESAGGGSFLVIPLEQTGRIEPNYPKVCGHQGNVLDIKWNPFIDNIIASCSEDTSVRI 114
           +VT    G  ++  P       E +      H  +V D++W+P   N+ ASCS D ++RI
Sbjct: 747 LVTGDCTGAIYISQPSSSGWTTEKS--SYAAHTDSVEDVQWSPNEGNVFASCSVDRTLRI 920

Query: 115 WEIPDGGLKRNMTEALLELHGHSRRVGLVEWHPTTNNILFSAGYDYKVLIWNLDI--GEP 172
           W       K N+   L     HSR + ++ W+P   ++L S G D  + IW+L +   +P
Sbjct: 921 WNTQQKPSKANV---LTVPEAHSRDINVINWNPIEKHLLASGGDDGIIKIWDLRMFRNKP 1091

Query: 173 VKM---IDCHTDVILCMSFN-TDGSLLTTTCKDKKLRV 206
           V        H+  +  + +N  D S+L  + +D ++ +
Sbjct: 1092VSAQASFKLHSQPVTSLEWNPQDSSVLAASGEDDQITI 1205

 Score = 48.1 bits (113), Expect = 8e-06,   Method: Compositional matrix adjust.
 Identities = 24/85 (28%), Positives = 48/85 (56%)
 Frame = +3

Query: 85   GHQGNVLDIKWNPFIDNIIASCSEDTSVRIWEIPDGGLKRNMTEALLELHGHSRRVGLVE 144
             H  ++  I WNP   +++AS  +D  ++IW++     K    +A  +LH  S+ V  +E
Sbjct: 972  AHSRDINVINWNPIEKHLLASGGDDGIIKIWDLRMFRNKPVSAQASFKLH--SQPVTSLE 1145

Query: 145  WHPTTNNILFSAGYDYKVLIWNLDI 169
            W+P  +++L ++G D ++ IW+  +
Sbjct: 1146 WNPQDSSVLAASGEDDQITIWDFSV 1220
>01805
          Length = 2124

 Score = 61.2 bits (147), Expect = 9e-10,   Method: Compositional matrix adjust.
 Identities = 33/113 (29%), Positives = 52/113 (46%)
 Frame = -1

Query: 82  KVCGHQGNVLDIKWNPFIDNIIASCSEDTSVRIWEIPDGGLKRNMTEALLELHGHSRRVG 141
            V GH   VLD+ WN    +++AS S DT+V +W++ +G +  N T+       HSR V 
Sbjct: 591 SVTGHTQAVLDLSWNRNARHVLASASADTTVALWDLSEGKMAMNFTQ-------HSREVQ 433

Query: 142 LVEWHPTTNNILFSAGYDYKVLIWNLDIGEPVKMIDCHTDVILCMSFNTDGSL 194
              WHP     L +  +D             VK++DC +      S+  +G +
Sbjct: 432 CCNWHPQEEQTLLTGSFD-----------NTVKVVDCRSAETCHKSWTVEGEV 307
>12841
          Length = 1364

 Score = 53.5 bits (127), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 26/83 (31%), Positives = 45/83 (54%)
 Frame = +1

Query: 85   GHQGNVLDIKWNPFIDNIIASCSEDTSVRIWEIPDGGLKRNMTEALLELHGHSRRVGLVE 144
            GH   V  I+W+PF+ +I  SCS D S+R+W        ++ T  +L  H  ++ V  V 
Sbjct: 1042 GHTAPVYHIRWSPFVSDIFLSCSADWSIRLWH-------QDRTTPILTFHSSTKTVHDVC 1200

Query: 145  WHPTTNNILFSAGYDYKVLIWNL 167
            W P ++ + F+  ++  V +W+L
Sbjct: 1201 WSPRSSTV-FACVHEGAVEVWDL 1266

 Score = 31.6 bits (70), Expect = 0.69,   Method: Compositional matrix adjust.
 Identities = 17/63 (26%), Positives = 29/63 (46%), Gaps = 3/63 (4%)
 Frame = +1

Query: 128  EALLELH-GHSRRVGLVEWHPTTNNILFSAGYDYKVLIWNLDIGEPVKMIDCHTDVI--L 184
            E  LE + GH+  V  + W P  ++I  S   D+ + +W+ D   P+      T  +  +
Sbjct: 1018 EQYLETYSGHTAPVYHIRWSPFVSDIFLSCSADWSIRLWHQDRTTPILTFHSSTKTVHDV 1197

Query: 185  CMS 187
            C S
Sbjct: 1198 CWS 1206
>12574
          Length = 521

 Score = 49.7 bits (117), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 32/124 (25%), Positives = 59/124 (47%), Gaps = 3/124 (2%)
 Frame = +3

Query: 77  EPNYP---KVCGHQGNVLDIKWNPFIDNIIASCSEDTSVRIWEIPDGGLKRNMTEALLEL 133
           +P Y     + GH   +  +K++P  D  +AS S D  ++IW   DG  ++ +       
Sbjct: 147 KPTYTLKFTLAGHTKALSAVKFSPNGD-WLASSSADKLIKIWGAYDGKFEKTIA------ 305

Query: 134 HGHSRRVGLVEWHPTTNNILFSAGYDYKVLIWNLDIGEPVKMIDCHTDVILCMSFNTDGS 193
            GH   +  V W  + + +L SA  D  + IW    G+ +K +  H++ + C +FN   +
Sbjct: 306 -GHKLGLSDVAW-SSDSKLLCSASDDKTLKIWEFSTGKCMKTLKGHSNYVFCCNFNPQSN 479

Query: 194 LLTT 197
           L+ +
Sbjct: 480 LIVS 491
>00561
          Length = 1003

 Score = 47.4 bits (111), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 35/108 (32%), Positives = 56/108 (51%), Gaps = 3/108 (2%)
 Frame = -3

Query: 85  GHQGNVLDIKWNPFIDN-IIASCSEDTSVRIWEIPDGGLKRNMTEALLELHGHSRRVGLV 143
           GH   V  ++++P   N II SC  D +V++W + +  LK N        HGH+  +  V
Sbjct: 617 GHTDWVSCVRFSPNHSNPIIVSCGWDRTVKVWNLANCKLKNNH-------HGHNGYLNTV 459

Query: 144 EWHPTTNNILFSAGYDYKVLIWNLDIGEPVKMIDCHTDVI--LCMSFN 189
              P   ++  S G D K L+W+L+ G+ +  ++ H D+I  LC S N
Sbjct: 458 TVSP-DGSLCTSGGKDSKALLWDLNDGKNLYTLE-HNDIINALCFSPN 321

 Score = 39.7 bits (91), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 26/111 (23%), Positives = 52/111 (46%)
 Frame = -3

Query: 96  NPFIDNIIASCSEDTSVRIWEIPDGGLKRNMTEALLELHGHSRRVGLVEWHPTTNNILFS 155
           NP   + I S S D ++ +W++       N       L+GHS  +  V    +  N   S
Sbjct: 986 NPKDPDTIISASRDKTLIVWKLTRDE-DTNYGYPQKRLYGHSHFISDVV-LSSDGNYALS 813

Query: 156 AGYDYKVLIWNLDIGEPVKMIDCHTDVILCMSFNTDGSLLTTTCKDKKLRV 206
             +D  + +W+L  G+  +  + HT  +L ++F+ D   + +  +DK +++
Sbjct: 812 GSWDQTLRLWDLAAGKTTRRFEGHTKDVLSVAFSADNRQIVSGSRDKTIKL 660
>19949
          Length = 903

 Score = 47.0 bits (110), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 35/117 (29%), Positives = 56/117 (47%)
 Frame = +2

Query: 85  GHQGNVLDIKWNPFIDNIIASCSEDTSVRIWEIPDGGLKRNMTEALLELHGHSRRVGLVE 144
           GH G V  ++++P     IAS SED  V++W++  G L       L +L  H   V  +E
Sbjct: 113 GHTGCVCCLRFSP-DGRWIASASEDGLVKLWDLTAGKL-------LTDLKLHRDAVNTIE 268

Query: 145 WHPTTNNILFSAGYDYKVLIWNLDIGEPVKMIDCHTDVILCMSFNTDGSLLTTTCKD 201
           +HP    +L S   D  V  W+L+  + +   +   + I  + F+ DG  L +  KD
Sbjct: 269 FHP-HEFLLASGSADRTVKFWDLETFQLISTTEPEANSIRSILFHPDGVCLYSGSKD 436

 Score = 34.7 bits (78), Expect = 0.094,   Method: Compositional matrix adjust.
 Identities = 27/127 (21%), Positives = 57/127 (44%)
 Frame = +2

Query: 104 ASCSEDTSVRIWEIPDGGLKRNMTEALLELHGHSRRVGLVEWHPTTNNILFSAGYDYKVL 163
           AS S D +V++W+I   G        +    GH+  V  + + P    I  SA  D  V 
Sbjct: 41  ASGSMDCNVKLWDIRRKG-------CIYTYKGHTGCVCCLRFSPDGRWIA-SASEDGLVK 196

Query: 164 IWNLDIGEPVKMIDCHTDVILCMSFNTDGSLLTTTCKDKKLRVIEPRSGRVLQEANCKNH 223
           +W+L  G+ +  +  H D +  + F+    LL +   D+ ++  +  + +++     + +
Sbjct: 197 LWDLTAGKLLTDLKLHRDAVNTIEFHPHEFLLASGSADRTVKFWDLETFQLISTTEPEAN 376

Query: 224 RVNRVVF 230
            +  ++F
Sbjct: 377 SIRSILF 397
>01598
          Length = 1545

 Score = 46.2 bits (108), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 29/91 (31%), Positives = 43/91 (47%), Gaps = 1/91 (1%)
 Frame = +1

Query: 129  ALLELHGHSRRVGLVEWHPTTNNILFSAGYDYKVLIWNLDIGEPVKMIDCHTDVILCMSF 188
            +L EL GHS+RV  + W P  +  L S GYD +  +W++  G  +     H   +L   F
Sbjct: 1276 SLRELSGHSQRVTDMSWSPHHDARLVSVGYDAEAFVWDVQKGTALAQFKGHMGRLLTCQF 1455

Query: 189  NT-DGSLLTTTCKDKKLRVIEPRSGRVLQEA 218
            +  D  L+ T   D  + V      RV Q+A
Sbjct: 1456 SGLDPDLVMTGGSDASVHVW-----RVSQQA 1533

 Score = 40.4 bits (93), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 22/97 (22%), Positives = 43/97 (44%)
 Frame = +1

Query: 71   EQTGRIEPNYPKVCGHQGNVLDIKWNPFIDNIIASCSEDTSVRIWEIPDGGLKRNMTEAL 130
            ++T  I  +  ++ GH   V D+ W+P  D  + S   D    +W++  G        AL
Sbjct: 1252 KETSLILTSLRELSGHSQRVTDMSWSPHHDARLVSVGYDAEAFVWDVQKG-------TAL 1410

Query: 131  LELHGHSRRVGLVEWHPTTNNILFSAGYDYKVLIWNL 167
             +  GH  R+   ++     +++ + G D  V +W +
Sbjct: 1411 AQFKGHMGRLLTCQFSGLDPDLVMTGGSDASVHVWRV 1521
>12140
          Length = 727

 Score = 45.8 bits (107), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 36/101 (35%), Positives = 48/101 (47%), Gaps = 6/101 (5%)
 Frame = +2

Query: 71  EQTGRIEPNYPKVCGHQGNVLDIKWNPFID---NIIASCSEDTSVRIWEIPDGGLKRNMT 127
           ++TG +E    K+ GH   V D+ W P I    N+IASCS+D  V IW   + G     T
Sbjct: 314 DETGWVEDQ--KLEGHSDWVRDVAWAPSIGLPRNVIASCSQDCRVIIW--TNDGSSNQWT 481

Query: 128 EALLELHGHSRRVGLVEWH---PTTNNILFSAGYDYKVLIW 165
             +L       +   V WH     T NIL  +G D KV +W
Sbjct: 482 SRIL------NKFSDVVWHVSWSVTGNILAVSGGDNKVTLW 586
>01327
          Length = 2215

 Score = 45.8 bits (107), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 36/156 (23%), Positives = 71/156 (45%)
 Frame = +3

Query: 105 SCSEDTSVRIWEIPDGGLKRNMTEALLELHGHSRRVGLVEWHPTTNNILFSAGYDYKVLI 164
           S S+D SV +++  +G L+   T       GH R +  V +  + N  +FSA  D  + +
Sbjct: 90  SGSKDKSVVLYDYQNGRLEDRWT-------GHDREITKVCYGASCNG-MFSASRDKTIKM 245

Query: 165 WNLDIGEPVKMIDCHTDVILCMSFNTDGSLLTTTCKDKKLRVIEPRSGRVLQEANCKNHR 224
           W       ++    H  V+  +  NTD +LL +  +D  +R+ +  +G  L++ N   + 
Sbjct: 246 WQRGNSHSIRDFIGHDMVVTAIHLNTDNTLLCSGSRDNTVRIWDVETGACLRQNNIPQNL 425

Query: 225 VNRVVFLGNMKRLLTTGVSRWNTRQIALWDQEDLSM 260
           V  V +L     ++  G      +++ ++D   L +
Sbjct: 426 VTDVKWLPGSHLIIQAG----EDKEVRIYDSRTLGI 521

 Score = 27.7 bits (60), Expect = 9.3,   Method: Compositional matrix adjust.
 Identities = 27/85 (31%), Positives = 42/85 (49%), Gaps = 3/85 (3%)
 Frame = +3

Query: 85  GHQGNVLDIKWNPFIDN-IIASCSEDTSVRIWEIPDGGLKR--NMTEALLELHGHSRRVG 141
           GH   V  I  N   DN ++ S S D +VRIW++  G   R  N+ + L         V 
Sbjct: 285 GHDMVVTAIHLNT--DNTLLCSGSRDNTVRIWDVETGACLRQNNIPQNL---------VT 431

Query: 142 LVEWHPTTNNILFSAGYDYKVLIWN 166
            V+W P + +++  AG D +V I++
Sbjct: 432 DVKWLPGS-HLIIQAGEDKEVRIYD 503
>15780
          Length = 735

 Score = 45.8 bits (107), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 20/65 (30%), Positives = 38/65 (58%)
 Frame = -1

Query: 153 LFSAGYDYKVLIWNLDIGEPVKMIDCHTDVILCMSFNTDGSLLTTTCKDKKLRVIEPRSG 212
           L +AG D+ V++W++  G  V  +  HTD +  + F+ DG++L +   D  +R+ +    
Sbjct: 729 LSTAGADHTVIVWDIASGTAVAHLTAHTDTVYALCFSRDGTVLASGGMDNSIRLWDL--A 556

Query: 213 RVLQE 217
           RV++E
Sbjct: 555 RVMEE 541
>10264
          Length = 416

 Score = 45.8 bits (107), Expect = 4e-05,   Method: Composition-based stats.
 Identities = 29/91 (31%), Positives = 43/91 (47%), Gaps = 1/91 (1%)
 Frame = -1

Query: 129 ALLELHGHSRRVGLVEWHPTTNNILFSAGYDYKVLIWNLDIGEPVKMIDCHTDVILCMSF 188
           +L EL GHS+RV  + W P  +  L S GYD +  +W++  G  +     H   +L   F
Sbjct: 269 SLRELSGHSQRVTDMSWSPHHDARLVSVGYDAEAFVWDVQKGTALAQFKGHMGRLLTCQF 90

Query: 189 N-TDGSLLTTTCKDKKLRVIEPRSGRVLQEA 218
           +  D  L+ T   D  + V      RV Q+A
Sbjct: 89  SGLDPDLVMTGGSDASVHV-----WRVSQQA 12

 Score = 40.0 bits (92), Expect = 0.002,   Method: Composition-based stats.
 Identities = 20/86 (23%), Positives = 38/86 (44%)
 Frame = -1

Query: 82  KVCGHQGNVLDIKWNPFIDNIIASCSEDTSVRIWEIPDGGLKRNMTEALLELHGHSRRVG 141
           ++ GH   V D+ W+P  D  + S   D    +W++  G        AL +  GH  R+ 
Sbjct: 260 ELSGHSQRVTDMSWSPHHDARLVSVGYDAEAFVWDVQKG-------TALAQFKGHMGRLL 102

Query: 142 LVEWHPTTNNILFSAGYDYKVLIWNL 167
             ++     +++ + G D  V +W +
Sbjct: 101 TCQFSGLDPDLVMTGGSDASVHVWRV 24
>18981
          Length = 407

 Score = 43.5 bits (101), Expect = 2e-04,   Method: Composition-based stats.
 Identities = 25/92 (27%), Positives = 45/92 (48%)
 Frame = -2

Query: 98  FIDNIIASCSEDTSVRIWEIPDGGLKRNMTEALLELHGHSRRVGLVEWHPTTNNILFSAG 157
            +DN+I S + D ++R+W + +  L       L  L GH+  V  V  +      + S  
Sbjct: 394 LLDNMIISAATDRTLRVWCLKNTCL-------LHTLRGHNDDVECVCIY---GRRVVSGS 245

Query: 158 YDYKVLIWNLDIGEPVKMIDCHTDVILCMSFN 189
           +D  +++W +D G PV  +  HT+ I  + F+
Sbjct: 244 WDKTLIVWEVDTGRPVHQLHGHTEAITAVQFD 149
>17602
          Length = 481

 Score = 43.1 bits (100), Expect = 2e-04,   Method: Composition-based stats.
 Identities = 29/92 (31%), Positives = 48/92 (52%), Gaps = 1/92 (1%)
 Frame = +3

Query: 164 IWNLDIGEPVKMIDCHTDVILCMSFNTDGSLLTTTCKDKKLRVIEPRSGRVLQE-ANCKN 222
           IW++  G+ +K +  H+D +  + FN DGSL+ ++  D   R+ +  SG+ L    +  N
Sbjct: 6   IWDVKTGKCLKTLPAHSDPVTAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLXTLIDDDN 185

Query: 223 HRVNRVVFLGNMKRLLTTGVSRWNTRQIALWD 254
             V+ V F  N K +L   +   NT  + LWD
Sbjct: 186 PPVSFVKFSPNGKYILAATLD--NT--LKLWD 269
>07741
          Length = 2119

 Score = 42.7 bits (99), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 24/89 (26%), Positives = 42/89 (47%), Gaps = 3/89 (3%)
 Frame = +1

Query: 86  HQGNVLDIKWNPFIDNIIASCSEDTSVRIWE---IPDGGLKRNMTEALLELHGHSRRVGL 142
           H   V  + WN +   I A+CS D +V+IWE    P      +++   L     +  VG 
Sbjct: 238 HNMAVYKVAWNHYHPKIYATCSADWNVKIWENGGKPTDTGXDSLSRKPLFSFDLNNSVGD 417

Query: 143 VEWHPTTNNILFSAGYDYKVLIWNLDIGE 171
           V W P ++ +  +   D KV +++L + +
Sbjct: 418 VAWAPYSSTVFAAVTADGKVCVYDLSVNK 504
>19498
          Length = 903

 Score = 42.4 bits (98), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 28/81 (34%), Positives = 41/81 (50%)
 Frame = -1

Query: 85  GHQGNVLDIKWNPFIDNIIASCSEDTSVRIWEIPDGGLKRNMTEALLELHGHSRRVGLVE 144
           GH G+VLD+ W+P  D  +ASCS D ++ +W      LK   +E +  + GH+  V  V 
Sbjct: 615 GHAGDVLDLAWSPQ-DLWLASCSVDNTIVVWN----ALK--FSEQVAVIRGHAGMVKGVT 457

Query: 145 WHPTTNNILFSAGYDYKVLIW 165
           W P     L S   D  + +W
Sbjct: 456 WDP-VGRYLASQSDDKTLRVW 397
>30256
          Length = 961

 Score = 42.0 bits (97), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 29/114 (25%), Positives = 51/114 (44%)
 Frame = +3

Query: 103 IASCSEDTSVRIWEIPDGGLKRNMTEALLELHGHSRRVGLVEWHPTTNNILFSAGYDYKV 162
           + S S D ++R+W+I  G         L  L GH   V  V++       + S   DY V
Sbjct: 201 VVSGSRDATLRVWDIESG-------HCLNVLLGHMAAVRCVQYDGKR---VVSGAXDYTV 350

Query: 163 LIWNLDIGEPVKMIDCHTDVILCMSFNTDGSLLTTTCKDKKLRVIEPRSGRVLQ 216
            +W+ D    +  +  HT+ +  + F  DG  + +   D  +RV + R G+++ 
Sbjct: 351 RVWDPDTASCLHTLQGHTNRVYSLQF--DGVYVVSGSLDTSIRVWDVRCGKLVH 506

 Score = 37.4 bits (85), Expect = 0.013,   Method: Compositional matrix adjust.
 Identities = 30/120 (25%), Positives = 53/120 (44%), Gaps = 3/120 (2%)
 Frame = +3

Query: 85  GHQGNVLDIKWNPFIDNIIASCSEDTSVRIWEIPDGGLKRNMTEALLELHGHSRRVGLVE 144
           GH   V  ++++      + S S DTS+R+W++  G L       +  L GH      +E
Sbjct: 396 GHTNRVYSLQFDGVY---VVSGSLDTSIRVWDVRCGKL-------VHTLMGHQSLTSGLE 545

Query: 145 WHPTTNNILFSAGYDYKVLIWNLDIGEPVKMI---DCHTDVILCMSFNTDGSLLTTTCKD 201
                +N+L S   D  V +W++  G+ ++ +   + H   + C+ FN        TC D
Sbjct: 546 ---LKDNLLVSGNADSTVKVWDVHTGKCLQTLLGPNKHRSAVTCLQFNKK---FVVTCSD 707

 Score = 35.4 bits (80), Expect = 0.050,   Method: Compositional matrix adjust.
 Identities = 19/68 (27%), Positives = 31/68 (45%)
 Frame = +3

Query: 149 TNNILFSAGYDYKVLIWNLDIGEPVKMIDCHTDVILCMSFNTDGSLLTTTCKDKKLRVIE 208
           T N + S   D  + +WN D G     +  H+  + C+S +  G  + +  +D  LRV +
Sbjct: 69  TGNTVISGSTDRSLKVWNADTGVCTHTLYGHSSTVRCLSLS--GKKVVSGSRDATLRVWD 242

Query: 209 PRSGRVLQ 216
             SG  L 
Sbjct: 243 IESGHCLN 266

 Score = 28.9 bits (63), Expect = 4.9,   Method: Compositional matrix adjust.
 Identities = 16/75 (21%), Positives = 39/75 (52%)
 Frame = +3

Query: 100 DNIIASCSEDTSVRIWEIPDGGLKRNMTEALLELHGHSRRVGLVEWHPTTNNILFSAGYD 159
           DN++ S + D++V++W++  G       + LL  + H   V  ++++      + +   D
Sbjct: 552 DNLLVSGNADSTVKVWDVHTG----KCLQTLLGPNKHRSAVTCLQFNK---KFVVTCSDD 710

Query: 160 YKVLIWNLDIGEPVK 174
             V +W+L+ G+ ++
Sbjct: 711 GTVKLWDLNTGDFIR 755

 Score = 28.1 bits (61), Expect = 7.1,   Method: Compositional matrix adjust.
 Identities = 9/29 (31%), Positives = 18/29 (62%)
 Frame = +3

Query: 98  FIDNIIASCSEDTSVRIWEIPDGGLKRNM 126
           F    + +CS+D +V++W++  G   RN+
Sbjct: 675 FNKKFVVTCSDDGTVKLWDLNTGDFIRNL 761
>03156
          Length = 1014

 Score = 42.0 bits (97), Expect = 6e-04,   Method: Compositional matrix adjust.
 Identities = 28/126 (22%), Positives = 57/126 (45%)
 Frame = +1

Query: 135 GHSRRVGLVEWHPTTNNILFSAGYDYKVLIWNLDIGEPVKMIDCHTDVILCMSFNTDGSL 194
           GH R +  V +  + N  +FSA  D  + +W       ++    H  V+  +  NTD +L
Sbjct: 49  GHDREITKVCYGASCNG-MFSASRDKTIKMWQRGNSHSIRDFIGHDMVVTAIHLNTDNTL 225

Query: 195 LTTTCKDKKLRVIEPRSGRVLQEANCKNHRVNRVVFLGNMKRLLTTGVSRWNTRQIALWD 254
           L +  +D  +R+ +  +G  L++ N   + V  V +L     ++  G      +++ ++D
Sbjct: 226 LCSGSRDNTVRIWDVETGACLRQNNIPQNLVTDVKWLPGSHLIIQAG----EDKEVRIYD 393

Query: 255 QEDLSM 260
              L +
Sbjct: 394 SRTLGI 411

 Score = 28.1 bits (61), Expect = 7.9,   Method: Compositional matrix adjust.
 Identities = 27/85 (31%), Positives = 42/85 (49%), Gaps = 3/85 (3%)
 Frame = +1

Query: 85  GHQGNVLDIKWNPFIDN-IIASCSEDTSVRIWEIPDGGLKR--NMTEALLELHGHSRRVG 141
           GH   V  I  N   DN ++ S S D +VRIW++  G   R  N+ + L         V 
Sbjct: 175 GHDMVVTAIHLNT--DNTLLCSGSRDNTVRIWDVETGACLRQNNIPQNL---------VT 321

Query: 142 LVEWHPTTNNILFSAGYDYKVLIWN 166
            V+W P + +++  AG D +V I++
Sbjct: 322 DVKWLPGS-HLIIQAGEDKEVRIYD 393
>31474
          Length = 403

 Score = 41.6 bits (96), Expect = 8e-04,   Method: Composition-based stats.
 Identities = 29/95 (30%), Positives = 44/95 (46%), Gaps = 5/95 (5%)
 Frame = -3

Query: 82  KVC---GHQGNVLDIKWNPFIDNIIASCSEDTSVRIW--EIPDGGLKRNMTEALLELHGH 136
           +VC    H  +   + WNP    ++ASC  D  ++IW  E  +   K  +T+A      H
Sbjct: 329 EVCCLSAHDEHAWCVAWNP-TGTLLASCGSDKIIKIWGKEGDNWVCKSTLTDA------H 171

Query: 137 SRRVGLVEWHPTTNNILFSAGYDYKVLIWNLDIGE 171
           +R V  + W P   N L SA +D    +W+   GE
Sbjct: 170 TRTVRSLGWSP-CGNYLSSASFDATTAVWSRKGGE 69
>13335
          Length = 863

 Score = 40.8 bits (94), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 29/136 (21%), Positives = 61/136 (44%), Gaps = 5/136 (3%)
 Frame = +1

Query: 76  IEPNYPKVCGHQGNVLDIKWNPFIDNIIASCSEDTSVRIWEIPDGGLKRNMTEALLE--- 132
             P +   C    +  ++        ++A+  +D  +++W       +    E  L+   
Sbjct: 346 FSPTFGTACAENSSTCNL--------LLATGGKDNLIKLWTFS---AQVGSPEVTLQCRD 492

Query: 133 -LHGHSRRVGLVEWHPTTNNILFSAGYDYKVLIWNLDIGEPVKMID-CHTDVILCMSFNT 190
            L GHS  V    + P++  +L S  +D  V +W+   G  +  I+ CH+  + C +F+ 
Sbjct: 493 ILSGHSDLVMACAFSPSSA-LLASGSFDKSVRLWDSVKGVALFSIEACHSRFVTCCAFSI 669

Query: 191 DGSLLTTTCKDKKLRV 206
           DG+LL +   D+ +++
Sbjct: 670 DGTLLASGSMDRIIKI 717
>27475
          Length = 369

 Score = 40.4 bits (93), Expect = 0.001,   Method: Composition-based stats.
 Identities = 28/106 (26%), Positives = 52/106 (49%), Gaps = 4/106 (3%)
 Frame = +2

Query: 86  HQGNVLDIKWNPFIDNIIASCSEDTSVRIWEIPDGGLKRNMTEALLELHGHSRRVGLVEW 145
           H G V  + W+P  +++  S S D  +++W+       R+    L +++ H  R+  V+W
Sbjct: 65  HTGWVTGVDWSPTREHLFLSGSYDNVLKLWD------TRSPKATLYDMNWHEDRILAVDW 226

Query: 146 HPTTNNILFSAGYDYKVLIWNLD---IGEPVKMIDCHTD-VILCMS 187
             +   +L S G D K+ +++     +G    +IDC  D V+ C S
Sbjct: 227 --SIPELLLSGGVDNKLHVFSYSSAKLGTTD*LIDCACDYVV*CCS 358

 Score = 30.4 bits (67), Expect = 1.5,   Method: Composition-based stats.
 Identities = 23/82 (28%), Positives = 37/82 (45%), Gaps = 3/82 (3%)
 Frame = +2

Query: 136 HSRRVGLVEWHPTTNNILFSAGYDYKVLIWNLDIGEPVKMI---DCHTDVILCMSFNTDG 192
           H+  V  V+W PT  ++  S  YD  + +W  D   P   +   + H D IL + ++   
Sbjct: 65  HTGWVTGVDWSPTREHLFLSGSYDNVLKLW--DTRSPKATLYDMNWHEDRILAVDWSIP- 235

Query: 193 SLLTTTCKDKKLRVIEPRSGRV 214
            LL +   D KL V    S ++
Sbjct: 236 ELLLSGGVDNKLHVFSYSSAKL 301
>02090
          Length = 1841

 Score = 39.3 bits (90), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 21/66 (31%), Positives = 32/66 (48%)
 Frame = -3

Query: 152  ILFSAGYDYKVLIWNLDIGEPVKMIDCHTDVILCMSFNTDGSLLTTTCKDKKLRVIEPRS 211
            + FS   D  + +W+L     V+    HTD   C+  + DG+ L T   D  +R  + R 
Sbjct: 1584 VCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISPDGTKLWTGGLDNTVRSWDLRE 1405

Query: 212  GRVLQE 217
            GR LQ+
Sbjct: 1404 GRQLQQ 1387
>17598
          Length = 875

 Score = 39.3 bits (90), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 38/173 (21%), Positives = 72/173 (41%), Gaps = 5/173 (2%)
 Frame = +1

Query: 133 LHGHSRRVGLVEWHPTTNNILFSAGYDYKVLIWNLDIGEPVKMIDCHTDVILCMSFNTDG 192
           L GHS  V  V     +  +L S+ +D  + +W++  G   +    HT   L ++F+ D 
Sbjct: 109 LQGHSHFVSDVSLSADSRYVL-SSSWDATLRLWDIKKGNTTRRFISHTRDALAVAFSPDN 285

Query: 193 SLLTTTCKDKKLRVIEP-RSGRVLQEANCKNHRVNRVVFLGNMKRLLTTGVSRWNTRQIA 251
             + +  +DK L++       +   +AN     V  V F  + K  L    S    + I 
Sbjct: 286 RQIASGGRDKALKIWNTVGECKFTVDANSHQDWVTCVKFHQDAKSPLVVSASM--DKTIK 459

Query: 252 LWDQEDLSMPMI----EEEIDGLSGLLFPFYDADTHMLYLAGKGDGNIRYYEI 300
           +WD + +++       + +I+ +   L  +Y A       +G  DG +  + I
Sbjct: 460 VWDNQTMTLKHTFVGHKTQINAIDLALKTYYLA-------SGSKDGIVMTWNI 597

 Score = 28.9 bits (63), Expect = 4.4,   Method: Compositional matrix adjust.
 Identities = 20/81 (24%), Positives = 35/81 (43%)
 Frame = +1

Query: 102 IIASCSEDTSVRIWEIPDGGLKRNMTEALLELHGHSRRVGLVEWHPTTNNILFSAGYDYK 161
           ++ S S D ++++W+     LK           GH  ++  ++    T   L S   D  
Sbjct: 424 LVVSASMDKTIKVWDNQTMTLKHTFV-------GHKTQINAIDLALKTY-YLASGSKDGI 579

Query: 162 VLIWNLDIGEPVKMIDCHTDV 182
           V+ WN+  G  +  IDC  +V
Sbjct: 580 VMTWNIQNGTFLGKIDCDCEV 642
>27465
          Length = 658

 Score = 39.3 bits (90), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 24/100 (24%), Positives = 43/100 (43%)
 Frame = -1

Query: 107 SEDTSVRIWEIPDGGLKRNMTEALLELHGHSRRVGLVEWHPTTNNILFSAGYDYKVLIWN 166
           S D + +IW+           E L  L GH   V  + ++    + + +  +D    +W+
Sbjct: 304 SYDRTCKIWDTASA-------EELHTLEGHRNVVYAIAFNNPFGDKVITGSFDKTCKLWS 146

Query: 167 LDIGEPVKMIDCHTDVILCMSFNTDGSLLTTTCKDKKLRV 206
              G+    +  HT  I+C+SFN   +L+ T   D   R+
Sbjct: 145 TADGKCYHTLRGHTAEIVCVSFNPSSTLIATGSMDTTCRL 26

 Score = 34.3 bits (77), Expect = 0.12,   Method: Compositional matrix adjust.
 Identities = 28/125 (22%), Positives = 55/125 (44%), Gaps = 6/125 (4%)
 Frame = -1

Query: 53  LAIVTESAGGGSFLVIPLEQTGRI-----EPNYPKVCGHQGNVLDIKWN-PFIDNIIASC 106
           L  V  +  G SF+    ++T +I           + GH+  V  I +N PF D +I   
Sbjct: 352 LTNVAFNKSGSSFITGSYDRTCKIWDTASAEELHTLEGHRNVVYAIAFNNPFGDKVITG- 176

Query: 107 SEDTSVRIWEIPDGGLKRNMTEALLELHGHSRRVGLVEWHPTTNNILFSAGYDYKVLIWN 166
           S D + ++W   DG       +    L GH+  +  V ++P++  ++ +   D    +W+
Sbjct: 175 SFDKTCKLWSTADG-------KCYHTLRGHTAEIVCVSFNPSS-TLIATGSMDTTCRLWD 20

Query: 167 LDIGE 171
           ++  +
Sbjct: 19  VEKAQ 5
>02960
          Length = 1577

 Score = 37.7 bits (86), Expect = 0.010,   Method: Compositional matrix adjust.
 Identities = 27/106 (25%), Positives = 52/106 (49%), Gaps = 4/106 (3%)
 Frame = +2

Query: 86   HQGNVLDIKWNPFIDNIIASCSEDTSVRIWEIPDGGLKRNMTEALLELHGHSRRVGLVEW 145
            H G V  + W+P  +++  S S D  +++W+       R+    L +++ H  R+  V+W
Sbjct: 1211 HTGWVTGVDWSPTREHLFLSGSYDNVLKLWDT------RSPKATLYDMNWHEDRILAVDW 1372

Query: 146  HPTTNNILFSAGYDYKVLIWNLD---IGEPVKMIDCHTDVIL-CMS 187
              +   +L S G D K+ +++     +G    +IDC  D ++ C S
Sbjct: 1373 --SIPELLLSGGVDNKLHVFSYSSAKLGTTD*LIDCACDYVV*CCS 1504

 Score = 29.6 bits (65), Expect = 2.5,   Method: Compositional matrix adjust.
 Identities = 33/128 (25%), Positives = 58/128 (45%), Gaps = 3/128 (2%)
 Frame = +2

Query: 90   VLDIKWNPFIDNIIASCSEDTSVRIWEIPDGGLKRNMTEALLELHGHSRRVGLVEWHPTT 149
            VLD+ ++P + +++ + S D  VR+ + P       +  A      H+  V  V+W PT 
Sbjct: 1088 VLDVAYSP-LSHMLITGSADRHVRLVD-PRCSEGETVKCAFTS---HTGWVTGVDWSPTR 1252

Query: 150  NNILFSAGYDYKVLIWNLDIGEPVKMI---DCHTDVILCMSFNTDGSLLTTTCKDKKLRV 206
             ++  S  YD  + +W  D   P   +   + H D IL + ++    LL +   D KL V
Sbjct: 1253 EHLFLSGSYDNVLKLW--DTRSPKATLYDMNWHEDRILAVDWSIP-ELLLSGGVDNKLHV 1423

Query: 207  IEPRSGRV 214
                S ++
Sbjct: 1424 FSYSSAKL 1447
>27806
          Length = 419

 Score = 37.0 bits (84), Expect = 0.018,   Method: Composition-based stats.
 Identities = 22/78 (28%), Positives = 35/78 (44%)
 Frame = -1

Query: 102 IIASCSEDTSVRIWEIPDGGLKRNMTEALLELHGHSRRVGLVEWHPTTNNILFSAGYDYK 161
           II + S D + RI+ I  G         +L   GH   V  V +HP  + +L ++G D+ 
Sbjct: 383 IIGTASADHTARIYSIETGA-------CVLTYGGHQGSVNAVRFHPGQDLVLTASG-DHT 228

Query: 162 VLIWNLDIGEPVKMIDCH 179
             +W     +P  M D +
Sbjct: 227 AHVWRAQFSQPSLMSDLY 174
>12806
          Length = 961

 Score = 36.2 bits (82), Expect = 0.027,   Method: Compositional matrix adjust.
 Identities = 36/175 (20%), Positives = 71/175 (40%), Gaps = 4/175 (2%)
 Frame = +3

Query: 90  VLDIKWNPFIDNIIASCSEDTSVRIWEI---PDGGLKRNMTEALLELHGHSRRVGLVEWH 146
           V+D    PF+     S   D ++ +W++    DG   +        L GHS  +  +   
Sbjct: 27  VVDGATKPFL----ISGGRDNNIIVWDL*PKKDGDEDQTWGVPRKTLTGHSHFISDLALS 194

Query: 147 PTTNNILFSAGYDYKVLIWNLDIGEPVKMIDCHTDVILCMSFNTDGSLLTTTCKDKKLRV 206
             +     S+ +D  + +W++  G        HT  +L ++F+ D   + +  +DK L++
Sbjct: 195 ADSR-FALSSSWDATLRLWDIKKGSTTSRFINHTRDVLTVAFSPDNRQIASGGRDKNLKI 371

Query: 207 IEPRSG-RVLQEANCKNHRVNRVVFLGNMKRLLTTGVSRWNTRQIALWDQEDLSM 260
                  +   +AN     V  V F  + K  +    S  N + I +WD   +++
Sbjct: 372 WNIMGECKYTVDANAHTDWVTCVRFHQDTKNPIVVSAS--NDKTIKVWDNHTMTL 530

 Score = 34.3 bits (77), Expect = 0.11,   Method: Compositional matrix adjust.
 Identities = 24/88 (27%), Positives = 38/88 (43%)
 Frame = +3

Query: 102 IIASCSEDTSVRIWEIPDGGLKRNMTEALLELHGHSRRVGLVEWHPTTNNILFSAGYDYK 161
           I+ S S D ++++W+     LK           GH  ++  ++    + N L S   D  
Sbjct: 468 IVVSASNDKTIKVWDNHTMTLKNTFV-------GHKAQITALD---MSTNYLVSGSKDGI 617

Query: 162 VLIWNLDIGEPVKMIDCHTDVILCMSFN 189
            + WN+  G  V  IDC  D I  + FN
Sbjct: 618 AMTWNVAEGSFVGKIDCD-DQINAIKFN 698
>37142
          Length = 327

 Score = 36.2 bits (82), Expect = 0.032,   Method: Composition-based stats.
 Identities = 26/115 (22%), Positives = 53/115 (46%), Gaps = 4/115 (3%)
 Frame = +2

Query: 55  IVTESAGGGSFLVIPLEQT--GRIEPNYPKVCGHQGNVLDIKWNPFIDNIIASCSEDTSV 112
           ++   A  GS LV   ++   G  + +  ++  H G V  + +NPF  N++AS + ++ +
Sbjct: 2   VIVGGADNGSVLVYSAQKMIDGDADCSVLQLTKHTGAVKALDFNPFQTNLLASGASESEI 181

Query: 113 RIWEI--PDGGLKRNMTEALLELHGHSRRVGLVEWHPTTNNILFSAGYDYKVLIW 165
            IW++  PD  +         E       V  V W+    +IL ++ +  + ++W
Sbjct: 182 YIWDLNKPDNPMTPGQKSQPPE------EVSCVAWNRQVQHIL-ASNFAARCVVW 325
>10162
          Length = 1629

 Score = 35.4 bits (80), Expect = 0.054,   Method: Compositional matrix adjust.
 Identities = 29/126 (23%), Positives = 50/126 (39%), Gaps = 8/126 (6%)
 Frame = +3

Query: 182 VILCMSFNTDGSLLTTTCKDKKLRVIEPRSGRVLQEANC--------KNHRVNRVVFLGN 233
            ILC+  + D +L+ + C D   +V    SG++    NC        K++ V  V F   
Sbjct: 375 AILCVDCSADNALIMSGCADATAKVFNVSSGKLXSAFNCAASQDSQDKDNSVESVAFCPV 554

Query: 234 MKRLLTTGVSRWNTRQIALWDQEDLSMPMIEEEIDGLSGLLFPFYDADTHMLYLAGKGDG 293
                T      N+  + +W   DL   +         G+    + + T +LY A   DG
Sbjct: 555 SPYAATAT----NSGSVQVW---DLPTSVARHSFQHPEGVCKLQWSSSTALLYTACL-DG 710

Query: 294 NIRYYE 299
            +R ++
Sbjct: 711 VMRVWD 728
>01249
          Length = 1743

 Score = 35.0 bits (79), Expect = 0.069,   Method: Compositional matrix adjust.
 Identities = 25/116 (21%), Positives = 52/116 (44%), Gaps = 6/116 (5%)
 Frame = -1

Query: 103  IASCSEDTSVRIWEIPDGGLKRNMTEA------LLELHGHSRRVGLVEWHPTTNNILFSA 156
            +AS S D + ++W++  G L R M         +++   H    GL +      + LF  
Sbjct: 1161 VASSSSDGTCKLWDMLSGALLRTMVYETGVGCLIMDKQEHFLLAGL-DNGDILCSPLFGQ 985

Query: 157  GYDYKVLIWNLDIGEPVKMIDCHTDVILCMSFNTDGSLLTTTCKDKKLRVIEPRSG 212
                +V +         +++  H+D + C++F++DG  L +  ++ K+ +    SG
Sbjct: 984  ISQSEVFVSKHTTKAGERVLQGHSDAVTCLAFSSDGQRLASGSQNGKVIIWNMESG 817
>11493
          Length = 535

 Score = 34.3 bits (77), Expect = 0.12,   Method: Compositional matrix adjust.
 Identities = 40/168 (23%), Positives = 64/168 (38%), Gaps = 3/168 (1%)
 Frame = -2

Query: 41  HDNHFCAVNARFLAIVTESAGGGSFLVIPLEQTGRIEPNYPKVCGHQGNVL-DIKWNPFI 99
           H    CAV          + G G   V  + Q G   P     C  + N +  +K  P  
Sbjct: 480 HGEVVCAVTISNPTKYVYTGGKGCVKVWDISQPGNKNPVSQLDCLQRDNYIRSVKLLPDG 301

Query: 100 DNIIASCSEDTSVRIWEI--PDGGLKRNMTEALLELHGHSRRVGLVEWHPTTNNILFSAG 157
             +I    E +++ IW++  P   +K  +T A    +        +   P +  + FS  
Sbjct: 300 RTLIVG-GEASNLSIWDLASPTPRIKAELTSAAPACYA-------LAISPDSK-VCFSCC 148

Query: 158 YDYKVLIWNLDIGEPVKMIDCHTDVILCMSFNTDGSLLTTTCKDKKLR 205
            D  + +W+L     V+    HTD   C+  + DGS L T   D  +R
Sbjct: 147 SDGNIAVWDLHNEILVRQFQGHTDGASCIDISPDGSRLWTGGLDNTVR 4
>30108
          Length = 1032

 Score = 33.9 bits (76), Expect = 0.16,   Method: Compositional matrix adjust.
 Identities = 19/83 (22%), Positives = 41/83 (49%), Gaps = 2/83 (2%)
 Frame = +1

Query: 87  QGNVLDIKWNPFIDNIIASCSEDTSVRIWEIPDGGLKRNMTEALLELHGHSRRVGL--VE 144
           Q +V  + W P   +++A   + ++V IW I    L    + + +++  HS    +  + 
Sbjct: 226 QKSVAHLAWQPLSASVLAVACQ-SAVLIWHIEPTSLAARPSSSSVQVLQHSGHCPITHLA 402

Query: 145 WHPTTNNILFSAGYDYKVLIWNL 167
           W P+ N +L ++  D  V+ W++
Sbjct: 403 WLPSANILLSASPVDTAVMAWSV 471
>20662
          Length = 1220

 Score = 33.1 bits (74), Expect = 0.23,   Method: Compositional matrix adjust.
 Identities = 29/153 (18%), Positives = 59/153 (38%)
 Frame = +2

Query: 24  AANREHCFDGIPITKNVHDNHFCAVNARFLAIVTESAGGGSFLVIPLEQTGRIEPNYPKV 83
           A N + C  G+ +   + D  +   +   + + T     G   +  L+   ++       
Sbjct: 212 APNVDKCTAGVQLEAGLRDAAWVDSHKVLVGLDT-----GGVALWELQDEDKMFSMLSSA 376

Query: 84  CGHQGNVLDIKWNPFIDNIIASCSEDTSVRIWEIPDGGLKRNMTEALLELHGHSRRVGLV 143
           C H      +  N    + + S S D  +++W         ++T +L     HS  V  V
Sbjct: 377 CEHDDMTASVSINSDXSHYL-SASYDHGIKVWNT-------DLT-SLYTYRAHSDIVWDV 529

Query: 144 EWHPTTNNILFSAGYDYKVLIWNLDIGEPVKMI 176
           + HPT   +  S   D K+++W++   +P   +
Sbjct: 530 QCHPTEPALFLSCSQDGKIVLWDVRESKPATCL 628
>08355
          Length = 498

 Score = 32.3 bits (72), Expect = 0.46,   Method: Compositional matrix adjust.
 Identities = 12/31 (38%), Positives = 18/31 (58%)
 Frame = -1

Query: 85  GHQGNVLDIKWNPFIDNIIASCSEDTSVRIW 115
            H   +  + WN F  N+ A+CS D +V+IW
Sbjct: 93  AHNMAIYKVAWNRFHPNVYATCSADWNVKIW 1
>15745
          Length = 1183

 Score = 30.8 bits (68), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 23/106 (21%), Positives = 41/106 (38%), Gaps = 17/106 (16%)
 Frame = +2

Query: 82  KVCGHQGNVLDIKWNPFIDNIIASCSEDTS-------VRIWEIP----------DGGLKR 124
           +V    G V  I    F  +++A+C   TS         +W +P          D     
Sbjct: 212 RVSAQGGEVWHISAATFDSSLLATCYNKTSESKSELRAAVWRLPGDVDPSSPADDQSSSH 391

Query: 125 NMTEALLELHGHSRRVGLVEWHPTTNNILFSAGYDYKVLIWNLDIG 170
           +    L  LH     V  + WHPT ++       + +V++W+L++ 
Sbjct: 392 SSLLPLCHLHSSDHDVKGILWHPTGDSQTVLGVCEDRVIMWDLNVA 529

 Score = 30.8 bits (68), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 19/56 (33%), Positives = 26/56 (46%)
 Frame = +2

Query: 85  GHQGNVLDIKWNPFIDNIIASCSEDTSVRIWEIPDGGLKRNMTEALLELHGHSRRV 140
            H   V D+ +NP     +ASC +D  V+ W+       RN +E L  L  HS  V
Sbjct: 704 AHGQLVRDLDFNPNRQYYLASCGDDCRVKFWDT------RNCSEPLKVLSDHSHWV 853
>02948
          Length = 1207

 Score = 30.8 bits (68), Expect = 1.4,   Method: Compositional matrix adjust.
 Identities = 14/44 (31%), Positives = 22/44 (50%)
 Frame = -2

Query: 85   GHQGNVLDIKWNPFIDNIIASCSEDTSVRIWEIPDGGLKRNMTE 128
            GH+G V  +  NP     + SC  D ++ +W   DG L R+ + 
Sbjct: 1203 GHRGQVTGLALNPANKLQLLSCGLDGNINVWAYVDGVLLRSYSH 1072
>37180
          Length = 681

 Score = 30.4 bits (67), Expect = 1.7,   Method: Compositional matrix adjust.
 Identities = 23/73 (31%), Positives = 37/73 (50%), Gaps = 4/73 (5%)
 Frame = +3

Query: 101 NIIASCSEDTSVRIWEIPD---GGLKRNMTEALLELHGHSRRVGLVEWHPTTNNI-LFSA 156
           N IA   ++  VR+++I     G L R+  +      GH+R V  V W   +    LFS 
Sbjct: 318 NTIAIPHDNRHVRLYDINGVRIGRLPRSNRQ------GHTRMVCAVSWADESAPCNLFSC 479

Query: 157 GYDYKVLIWNLDI 169
           G+D +VL W++ +
Sbjct: 480 GFDRQVLGWHVSL 518
>01462
          Length = 995

 Score = 29.6 bits (65), Expect = 2.5,   Method: Compositional matrix adjust.
 Identities = 13/59 (22%), Positives = 30/59 (50%)
 Frame = +2

Query: 153 LFSAGYDYKVLIWNLDIGEPVKMIDCHTDVILCMSFNTDGSLLTTTCKDKKLRVIEPRS 211
           L++   D K+ +W+++ G+ +  ++ H D I  +    D     +  +D  +R+ + RS
Sbjct: 242 LYAGAGDRKIHVWDIEAGQYLNAMEGHKDYIHKVVMKNDAQECVSASEDGTVRMWDIRS 418
>25400
          Length = 462

 Score = 29.6 bits (65), Expect = 2.7,   Method: Composition-based stats.
 Identities = 13/35 (37%), Positives = 22/35 (62%)
 Frame = +3

Query: 85  GHQGNVLDIKWNPFIDNIIASCSEDTSVRIWEIPD 119
           GH+  V D+ W+P+ + +I+S S D +V  W+  D
Sbjct: 84  GHRSCVRDVSWHPYTNTLISS-SWDGTVGKWDYFD 185
>27562
          Length = 399

 Score = 29.3 bits (64), Expect = 3.5,   Method: Composition-based stats.
 Identities = 18/57 (31%), Positives = 28/57 (49%)
 Frame = -3

Query: 381 PDEWLGGINRDPVLMSLKEGYKKSSKVVFKAPIREKKSVVVNGIDLLENVPPRTENE 437
           P+  L G+    V    +EGY  S++ +F+ P+R+         D LE  P RT+ E
Sbjct: 250 PEADLTGLMESVVDSDEEEGYADSTEALFQFPVRDTVR------DCLEKRPIRTDGE 98
>00825
          Length = 1821

 Score = 28.9 bits (63), Expect = 4.3,   Method: Compositional matrix adjust.
 Identities = 22/79 (27%), Positives = 37/79 (46%)
 Frame = -2

Query: 93   IKWNPFIDNIIASCSEDTSVRIWEIPDGGLKRNMTEALLELHGHSRRVGLVEWHPTTNNI 152
            + WNP     I S +ED ++  +++    +  NM         H+  V  V++ PT    
Sbjct: 1343 LSWNPMEAFTITSANEDGNLYTFDMRKLSMPLNMHR------DHTAAVMDVDYCPTGREF 1182

Query: 153  LFSAGYDYKVLIWNLDIGE 171
            + SAGYD  + I+ +D G 
Sbjct: 1181 V-SAGYDKVIRIFPVDKGH 1128
>30176
          Length = 365

 Score = 28.9 bits (63), Expect = 4.6,   Method: Composition-based stats.
 Identities = 20/75 (26%), Positives = 39/75 (52%), Gaps = 12/75 (16%)
 Frame = +2

Query: 95  WNPFIDNI---IASCSEDTSVRIWE-----IPDGGLKRNMT---EALLELHGH-SRRVGL 142
           WN   D     +ASCS+D +++IW+      P+G + ++     + +  L G+ SR +  
Sbjct: 32  WNLTFDKTGTRLASCSDDKTIKIWQEYLPGNPEGIVTKDNEPTWKCVCTLGGYTSRALYD 211

Query: 143 VEWHPTTNNILFSAG 157
           ++W   T +I+ + G
Sbjct: 212 IDWSHLTGDIVTAGG 256
>02828
          Length = 1813

 Score = 28.5 bits (62), Expect = 6.7,   Method: Compositional matrix adjust.
 Identities = 22/75 (29%), Positives = 32/75 (42%), Gaps = 8/75 (10%)
 Frame = +1

Query: 302 TEKPYLSYLMEFRSPAPQKGLGVMPKHGLDVSACEVFRFYKLVTLKGLIEPISMIVPR-- 359
           + K  L  L  FRS +PQ+G+   P  GL       +     +T   L+ P+S       
Sbjct: 730 SSKIALKLLFSFRSRSPQQGVAPAPDRGLSGPWTXAYLPLFSLTPNSLLCPLSSSFSSSS 909

Query: 360 ------RSDSYQEDI 368
                 +S S+QEDI
Sbjct: 910 SFCQGLKSSSFQEDI 954
>06078
          Length = 1315

 Score = 28.5 bits (62), Expect = 6.7,   Method: Compositional matrix adjust.
 Identities = 32/131 (24%), Positives = 51/131 (38%), Gaps = 3/131 (2%)
 Frame = +1

Query: 302 TEKPYLSYLMEFRSPAPQKGLGVMPKHGLDVSACEVFR---FYKLVTLKGLIEPISMIVP 358
           T  P +    + +  +P+K LG       D+S C + +    YKL T  GL +    +  
Sbjct: 496 TSSPEMFNNSKHQHQSPKKQLGFR-----DLSTCXISKGSVCYKLSTSLGLAD--VKVSA 654

Query: 359 RRSDSYQEDIYPMTPGTEPALTPDEWLGGINRDPVLMSLKEGYKKSSKVVFKAPIREKKS 418
             SDS  E+   M        TP+ W        +L S  EG        F++  RE++ 
Sbjct: 655 EDSDSGSENDSAMCFSARTFWTPENWKEVKKCSSILQSNYEG--------FESAARERQL 810

Query: 419 VVVNGIDLLEN 429
           +    +  L N
Sbjct: 811 METEALQSLSN 843
>29912
          Length = 510

 Score = 28.1 bits (61), Expect = 8.0,   Method: Compositional matrix adjust.
 Identities = 24/112 (21%), Positives = 47/112 (41%), Gaps = 6/112 (5%)
 Frame = +3

Query: 101 NIIASCSEDTSVRIWEIPDGGLKRNMTEALLELHGHSRRVGLVEWHPTTNNILFSAG--- 157
           N +A  +    V++W++      R M        GH+ RVG + W    N+ + S+G   
Sbjct: 48  NYLALGTSTGEVQVWDVTQQKKLRTMA-------GHAARVGSLSW----NSFIVSSGSRS 194

Query: 158 ---YDYKVLIWNLDIGEPVKMIDCHTDVILCMSFNTDGSLLTTTCKDKKLRV 206
              + + V + +  +G     +  H+  +  + ++ DG  L +   D  L V
Sbjct: 195 GNIHHHDVRVADHHVG----TLSGHSQEVCGLRWSPDGKYLASGANDNLLCV 338
>17266
          Length = 480

 Score = 28.1 bits (61), Expect = 8.1,   Method: Compositional matrix adjust.
 Identities = 26/122 (21%), Positives = 54/122 (44%), Gaps = 2/122 (1%)
 Frame = -1

Query: 85  GHQGNVLDIKWNPFIDNIIASCSEDTSVRIWEIPDGGLKRNMTEALLELHGHSRRV-GLV 143
           GH+ ++  I + P   +  A+ S+D + R+++I          +  + ++ H   + G+ 
Sbjct: 339 GHESDINAITYFP-NGHAFATGSDDATCRLFDIR--------ADQEIGMYSHDNIICGIT 187

Query: 144 EWHPTTNNILFSAGYD-YKVLIWNLDIGEPVKMIDCHTDVILCMSFNTDGSLLTTTCKDK 202
               + +  L   GYD +   IW++   E   ++  H + + C+    DGS + T   D 
Sbjct: 186 SVAFSKSGRLLLGGYDDFNCNIWDVLKQERTGVLAGHDNRVSCLGVTEDGSAVATGSWDS 7

Query: 203 KL 204
            L
Sbjct: 6   FL 1
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|61097906|ref|NP_598917.1| actinin, alpha 1 [Mus
musculus]
         (892 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

17613                                                                 190   2e-75
19002                                                                 267   1e-71
19147                                                                 193   2e-51
29426                                                                 127   2e-29
29446                                                                  99   6e-21
05733                                                                  86   7e-17
34417                                                                  77   2e-14
32371                                                                  50   9e-12
14594                                                                  59   7e-09
22063                                                                  55   1e-07
14945                                                                  55   1e-07
18202                                                                  53   6e-07
01375                                                                  50   4e-06
09711                                                                  49   7e-06
18556                                                                  48   1e-05
38338                                                                  40   0.005
32088                                                                  40   0.005
28965                                                                  39   0.008
04951                                                                  39   0.008
20251                                                                  38   0.023
38533                                                                  37   0.028
03732                                                                  32   1.2  
14027                                                                  30   4.9  
30240                                                                  30   5.4  
>17613
          Length = 1108

 Score =  184 bits (468), Expect(2) = 2e-75,   Method: Compositional matrix adjust.
 Identities = 86/133 (64%), Positives = 108/133 (81%)
 Frame = +3

Query: 214 RFLDIPKMLDAEDIVGTARPDEKAIMTYVSSFYHAFSGAQKAETAANRICKVLAVNQENE 273
           + LDIP+MLD ED+V +A+PDE+++M YVSS+YHAFSGAQ+AETAANRICKVL VNQENE
Sbjct: 390 KHLDIPRMLDPEDMVNSAKPDERSVMAYVSSYYHAFSGAQQAETAANRICKVLKVNQENE 569

Query: 274 QLMEDYEKLASDLLEWIRRTIPWLENRVPENTMHAMQQKLEDFRDYRRLHKPPKVQEKCQ 333
           +LME+YE+LASDLLEWIRRT PWLENRV +NT+   + KL++FRDYRR  KPP  + +  
Sbjct: 570 RLMEEYERLASDLLEWIRRTRPWLENRVTDNTLPGTRHKLDEFRDYRRKQKPPSWRTR-- 743

Query: 334 LEINFNTLQTKLR 346
              ++ TL T  R
Sbjct: 744 --PSWRTLSTPCR 776

 Score =  117 bits (294), Expect(2) = 2e-75,   Method: Compositional matrix adjust.
 Identities = 63/133 (47%), Positives = 78/133 (58%), Gaps = 4/133 (3%)
 Frame = +1

Query: 85  MRVHKISNVNKALDFI----ASKGVKLVSIGAEEIVDGNVKMTLGMIWTIILRFAIQDIS 140
           MR HKI+NVNKALD+I       G+             +++  L     +          
Sbjct: 4   MRFHKIANVNKALDYIDLQRGQTGLHRSRRNC*RQRKDDIRYDLDNYPQV----CHPRHH 171

Query: 141 VEETSAKEGLLLWCQRKTAPYKNVNIQNFHISWKDGLGFCALIHRHRPELIDYGKLRKDD 200
              T  +   ++    KTAPYKNVN+QNFH+S+KDGL FCALIHRHRPELIDY  L KD+
Sbjct: 172 SRRTHCQRRTVIVVPAKTAPYKNVNVQNFHLSFKDGLAFCALIHRHRPELIDYHSLSKDN 351

Query: 201 PLTNLNTAFDVAE 213
           PL NLNTAFD+AE
Sbjct: 352 PLENLNTAFDIAE 390

 Score =  190 bits (482), Expect = 3e-48,   Method: Compositional matrix adjust.
 Identities = 88/128 (68%), Positives = 111/128 (86%)
 Frame = +2

Query: 326 PKVQEKCQLEINFNTLQTKLRLSNRPAFMPSEGRMVSDINNAWGCLEQAEKGYEEWLLNE 385
           PK+++K +LE +FNTLQT+LRLSNRPA++P+EG+MVSDI NAW  LE AEKG+EEWLL+E
Sbjct: 725 PKLEDKAKLENSFNTLQTRLRLSNRPAYLPTEGKMVSDIANAWKGLEHAEKGFEEWLLSE 904

Query: 386 IRRLERLDHLAEKFRQKASIHEAWTDGKEAMLRQKDYETATLSEIKALLKKHEAFESDLA 445
           ++RLERLDHLA+KFR K  IHE W+ GKE ML+ +D++   L+E+KA+ KKHEAFESDLA
Sbjct: 905 LQRLERLDHLAQKFRHKCEIHEEWSQGKEDMLQSRDFKQCRLNELKAMKKKHEAFESDLA 1084

Query: 446 AHQDRVEQ 453
           AHQDRVEQ
Sbjct: 1085AHQDRVEQ 1108
>19002
          Length = 842

 Score =  267 bits (683), Expect = 1e-71,   Method: Compositional matrix adjust.
 Identities = 141/283 (49%), Positives = 185/283 (65%), Gaps = 8/283 (2%)
 Frame = -2

Query: 61  DGLKLMLLLEVISGERLAKPERGKMRVHKISNVNKALDFIASKGVKLVSIGAEEIVDGNV 120
           DG  LM LLEV     +A   +GKMR+H + NV+KAL F+  + V L ++GA +IVDG+ 
Sbjct: 841 DGKMLMKLLEVRVRGEIASDXKGKMRIHCLENVDKALTFLHEQRVHLENMGAHDIVDGSS 662

Query: 121 KMTLGMIWTIILRFAIQDISVEET------SAKEGLLLWCQRKTAPYKNVNIQNFHISWK 174
           ++TLG+IWTIILRF IQDI +EE       SAK+ LLLWCQ KTA Y NVN++NF  SW+
Sbjct: 661 RLTLGLIWTIILRFQIQDIMIEEVDNSETKSAKDALLLWCQMKTAGYPNVNVRNFTTSWR 482

Query: 175 DGLGFCALIHRHRPELIDYGKLRKDDPLTNLNTAFDVAERFLDIPKMLDAEDIVGTARPD 234
           DGL F A+IH+HRP+L+ Y +L K   + NL  AF VAE  L +  +L+ ED V    PD
Sbjct: 481 DGLAFNAIIHKHRPDLVQYDRLHKSSAIQNLQNAFTVAEDKLGLTALLEPED-VNVEYPD 305

Query: 235 EKAIMTYVSSFYHAFSGAQKAETAANRICKVL--AVNQENEQLMEDYEKLASDLLEWIRR 292
           EK+I+TYV ++YH FS  +       RI KV+  A+N EN   +E+YE L SDLLEWI +
Sbjct: 304 EKSIITYVVTYYHYFSKMKADSVQGKRIGKVIDNAINTENS--IEEYETLTSDLLEWIEQ 131

Query: 293 TIPWLENRVPENTMHAMQQKLEDFRDYRRLHKPPKVQEKCQLE 335
           TI  L +R   N++  +QQ+L  F  YR + KPPK  EK  LE
Sbjct: 130 TIVILRDRQFANSLTGVQQQLAAFNTYRIVEKPPKFDEKGNLE 2
>19147
          Length = 474

 Score =  193 bits (491), Expect(2) = 2e-51,   Method: Compositional matrix adjust.
 Identities = 90/108 (83%), Positives = 97/108 (89%)
 Frame = +1

Query: 98  DFIASKGVKLVSIGAEEIVDGNVKMTLGMIWTIILRFAIQDISVEETSAKEGLLLWCQRK 157
            +IASKGVKLVSIGAEEIVDGNVKMTLGMIWTIILRFAIQDI+VEE +AKEGLLLWCQRK
Sbjct: 46  SYIASKGVKLVSIGAEEIVDGNVKMTLGMIWTIILRFAIQDITVEELTAKEGLLLWCQRK 225

Query: 158 TAPYKNVNIQNFHISWKDGLGFCALIHRHRPELIDYGKLRKDDPLTNL 205
           TAPYKNVN+QNFH+S+KDGL FCALIHRHRPELIDY  L K   L  +
Sbjct: 226 TAPYKNVNVQNFHLSFKDGLAFCALIHRHRPELIDYHSLSKVSLLNTV 369

 Score = 28.1 bits (61), Expect(2) = 2e-51,   Method: Composition-based stats.
 Identities = 12/16 (75%), Positives = 14/16 (87%)
 Frame = +3

Query: 84 KMRVHKISNVNKALDF 99
          KMR HKI+NVNKAL+ 
Sbjct: 3  KMRFHKIANVNKALEL 50
>29426
          Length = 361

 Score =  127 bits (319), Expect = 2e-29,   Method: Compositional matrix adjust.
 Identities = 62/121 (51%), Positives = 84/121 (69%), Gaps = 1/121 (0%)
 Frame = -2

Query: 537 IVHTIEEIQGLTTAHEQFKATLPDADKERLAILGIHNEVSKIVQTYHVNMAGTNPYTTIT 596
           IVHT EE++GL  AHEQFKATL +ADKE   I+ +  EV+ + Q Y +     NPYTT+ 
Sbjct: 360 IVHTTEEVEGLVDAHEQFKATLGEADKEYSTIVSLSQEVASLGQQYDLTPPD-NPYTTLH 184

Query: 597 PQE-INGKWDHVRQLVPRRDQALTEEHARQQHNERLRKQFGAQANVIGPWIQTKMEEIGR 655
            QE I  KW  VR+LVPRRDQ L +E  RQQ+NERLR+QF  +AN +G WI+++++ +  
Sbjct: 183 AQEDITNKWSEVRELVPRRDQTLQQEMTRQQNNERLRRQFATKANTVGQWIESQLDAVAS 4

Query: 656 I 656
           +
Sbjct: 3   L 1
>29446
          Length = 1445

 Score = 99.4 bits (246), Expect = 6e-21,   Method: Compositional matrix adjust.
 Identities = 60/165 (36%), Positives = 90/165 (54%), Gaps = 11/165 (6%)
 Frame = +3

Query: 20   DRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRDGLKLMLLLEVISGERLAK 79
            +R+L  D  W+  Q+ TFT W N HLR     I ++E DF DGL+L+ L+EV+SG++   
Sbjct: 963  ERELAEDAQWKIIQKNTFTRWANEHLRTVNKAIADLESDFSDGLRLVALIEVLSGKKFKH 1142

Query: 80   P-ERGKMRVHKISNVNKALDFIA-SKGVKLVSIGAEEIVDGNVKMTLGMIWTIILRFAIQ 137
              +R   R  K+ NV   L F+   +G+++V+I + +IVD  +K+ LG+IWT+IL ++I 
Sbjct: 1143 VNKRPNFRTQKLENVTLTLKFLEDDEGIRIVNIDSTDIVDKKLKLILGLIWTLILHYSIS 1322

Query: 138  --DISVEETSAKEG-------LLLWCQRKTAPYKNVNIQNFHISW 173
                  EE +  EG       LL W Q K      +  Q  H  W
Sbjct: 1323 MPMWEGEEPTPSEGGPTPKQRLLNWIQSKVP----IAHQELHHRW 1445
>05733
          Length = 1021

 Score = 85.9 bits (211), Expect = 7e-17,   Method: Compositional matrix adjust.
 Identities = 42/102 (41%), Positives = 59/102 (57%), Gaps = 2/102 (1%)
 Frame = +2

Query: 150 LLLWCQR--KTAPYKNVNIQNFHISWKDGLGFCALIHRHRPELIDYGKLRKDDPLTNLNT 207
           LL WCQR      Y+ V+I +F  SW+ GL FCALIH  RP LI    L + + + N   
Sbjct: 470 LLRWCQRVLNXGTYRGVHIIDFTSSWRSGLAFCALIHAFRPHLISPASLMECETVKNNQL 649

Query: 208 AFDVAERFLDIPKMLDAEDIVGTARPDEKAIMTYVSSFYHAF 249
           AFDVA++ L I  ++  ED+   A PD+  ++ Y+S F+  F
Sbjct: 650 AFDVAQKELGIAPVMRGEDMAACAVPDKLTMVAYLSQFHELF 775
>34417
          Length = 1096

 Score = 77.4 bits (189), Expect = 2e-14,   Method: Composition-based stats.
 Identities = 34/74 (45%), Positives = 44/74 (59%)
 Frame = +2

Query: 173 WKDGLGFCALIHRHRPELIDYGKLRKDDPLTNLNTAFDVAERFLDIPKMLDAEDIVGTAR 232
           W +GL FCALIH   P+  DY +L+  +   N   AFD AE+  DI  +LD ED++    
Sbjct: 47  WNNGLAFCALIHHFYPDAFDYSQLQPQNRRYNFELAFDTAEKLADISPLLDVEDMIKMKN 226

Query: 233 PDEKAIMTYVSSFY 246
           PD K + TYV SFY
Sbjct: 227 PDWKCVFTYVQSFY 268
>32371
          Length = 625

 Score = 50.1 bits (118), Expect(2) = 9e-12,   Method: Compositional matrix adjust.
 Identities = 25/48 (52%), Positives = 32/48 (66%)
 Frame = -2

Query: 188 PELIDYGKLRKDDPLTNLNTAFDVAERFLDIPKMLDAEDIVGTARPDE 235
           P+LIDY  L K++ L N N AF VAE+ LDIP  L+A D+V    PD+
Sbjct: 549 PDLIDYDSLSKENVLYNNNLAFTVAEQELDIPAFLEAADMVALRTPDK 406

 Score = 38.5 bits (88), Expect(2) = 9e-12,   Method: Composition-based stats.
 Identities = 13/25 (52%), Positives = 21/25 (84%)
 Frame = -1

Query: 163 NVNIQNFHISWKDGLGFCALIHRHR 187
           +V+I++  +SW++GL FCA+IHR R
Sbjct: 625 SVDIKDLLVSWRNGLAFCAIIHRFR 551
>14594
          Length = 1014

 Score = 59.3 bits (142), Expect = 7e-09,   Method: Compositional matrix adjust.
 Identities = 35/108 (32%), Positives = 61/108 (56%), Gaps = 1/108 (0%)
 Frame = +3

Query: 743 ISQEQMNEFRASFNHFDRDHSGTLGPEEFKACLISLGYDIGNDPQGEAEFARIMSIVDPN 802
           ++ EQ+ EF+ +F+ FD+D  GT+   E    + SL    G +P  E E   +++ VD +
Sbjct: 423 LTDEQVAEFKEAFSLFDKDGDGTITTSELGTVMRSL----GQNPT-ENELQDMINEVDAD 587

Query: 803 RLGVVTFQAFIDFMSRETADTDTADQVMASFKILAGDKN-YITEDELR 849
             G + F+ F+  M+R+  DTD  +++  +F++   D N YI+  ELR
Sbjct: 588 GNGTIDFEEFLHMMARKMKDTDCEEELREAFRVFDKDGNGYISAAELR 731
>22063
          Length = 688

 Score = 54.7 bits (130), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 30/112 (26%), Positives = 63/112 (56%), Gaps = 3/112 (2%)
 Frame = +3

Query: 743 ISQEQMNEFRASFNHFDRDHSGTLGPEEFKACLISLGYDIGNDPQGEAEFARIMSIVDPN 802
           +++EQ  E R +F+ FD D SGT+  +E K  + +LG+    +P+ E E  ++++ +D  
Sbjct: 153 LTEEQKQEIREAFDLFDADGSGTIDAKELKVAMRALGF----EPKKE-EIKKMIAEIDKE 317

Query: 803 RLGVVTFQAFIDFMSRETADTDTADQVMASFKILAGD---KNYITEDELRRE 851
             G + F  F+  M+++ ++ D  ++++ +F++   D   KN   + E  R+
Sbjct: 318 GTGTIDFNDFLTIMTQKMSEKDAKEEILKAFRLFDDDETGKNLFPQFETSRK 473
>14945
          Length = 1337

 Score = 54.7 bits (130), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 26/97 (26%), Positives = 57/97 (58%)
 Frame = +1

Query: 743 ISQEQMNEFRASFNHFDRDHSGTLGPEEFKACLISLGYDIGNDPQGEAEFARIMSIVDPN 802
           +++EQ  E R +F+ FD D SGT+  +E K  + +LG+    +P+ E E  ++++ +D  
Sbjct: 94  LTEEQKQEIREAFDLFDADGSGTIDAKELKVAMRALGF----EPKKE-EIKKMIAEIDKE 258

Query: 803 RLGVVTFQAFIDFMSRETADTDTADQVMASFKILAGD 839
             G + F  F+  M+++ ++ D  ++++ +F++   D
Sbjct: 259 GTGTIDFNDFLTIMTQKMSEKDAKEEILKAFRLFDDD 369
>18202
          Length = 424

 Score = 52.8 bits (125), Expect = 6e-07,   Method: Composition-based stats.
 Identities = 35/127 (27%), Positives = 70/127 (55%), Gaps = 6/127 (4%)
 Frame = -1

Query: 35  KTFTAWCNSHLRKAGTQIENIEEDFRDGLKLMLLLEVISGER-LAKPERGKMRVHKISNV 93
           + + +W NS L +  + +EN+    ++G  L  L++V++ E  L    +   +  + + +
Sbjct: 385 QVYLSWANSVLCEVNSSVENVSS-IQEGRVLCELIDVLAPEAGLLDKVQASGKSGQRAFI 209

Query: 94  NKALDFIASKGVKLVSIGAEEIVDGNVKMTLGMIWTIILRFAIQDI---SVEET--SAKE 148
             ALD + + G+K+V    ++I+DG++K  L ++W +IL + I  I   S + +  + K+
Sbjct: 208 YAALDHMKNHGIKIV-FSTQDIMDGDIKSLLDVMWLLILNYGIHFIGNNSFQRSVGAGKK 32

Query: 149 GLLLWCQ 155
            LL WCQ
Sbjct: 31  NLLDWCQ 11
>01375
          Length = 2323

 Score = 50.1 bits (118), Expect = 4e-06,   Method: Composition-based stats.
 Identities = 26/71 (36%), Positives = 42/71 (59%), Gaps = 3/71 (4%)
 Frame = +1

Query: 820 TADTDTADQVMASFKIL-AGDKNYITEDELRRELPPDQAEYCIARMAPYAGPD--SVPGA 876
           T +  ++ +V  +F+ L +G+K +IT  EL   L  +QA+YCI RM PY      ++P A
Sbjct: 4   TENVQSSSEVEQAFRALTSGEKPFITAQELYANLTKEQADYCIGRMQPYVDKTGRTIPDA 183

Query: 877 LDYMSFSTALY 887
            DY+ F+  L+
Sbjct: 184 YDYVDFTRQLF 216
>09711
          Length = 3041

 Score = 49.3 bits (116), Expect = 7e-06,   Method: Compositional matrix adjust.
 Identities = 65/267 (24%), Positives = 114/267 (42%), Gaps = 25/267 (9%)
 Frame = +1

Query: 30   EKQQRKTFTAWCNSHLRKAGTQIENIEEDFRDGLKLMLLLEVIS------GERLAKPERG 83
            E ++ KT+  W NS        + ++  D  DGL +  L + I        +   K  + 
Sbjct: 841  ESREEKTYRNWMNS--LGVSPFVHHLYSDLYDGLIIFQLYDYIQPGLVDWSKVKKKFNKL 1014

Query: 84   KMRVHKISNVNKALDF---IASKGVKLVSIGAEEIVDGNVKMTLGMIWTIILRFAIQDIS 140
            K R  +I N N A++    +    VKLV I  ++I+DGN  +TLG++W ++  + +  +S
Sbjct: 1015 KARFERIENCNYAVELGPQVKLVKVKLVGIAGQDILDGNPVLTLGLVWQLMRAYTLAILS 1194

Query: 141  -VEETS---AKEGLLLWCQRKTAPYKNVNIQNFH-ISWKDGLGFCALIHRHRPELIDYGK 195
             + E +   +   ++ W   K    K+  I  F      DG+    +I   +P ++++  
Sbjct: 1195 KITENNKPISDNEIITWVNSKIK--KDDRISGFQDRKLNDGVIVARVIEAIKPGIVNWDN 1368

Query: 196  LRKD-----DPLTNLNTAFDVAERFLDIPKMLDAEDIVGTARPDEKAIMTYVSSFYHAFS 250
            +        D LTN   A  +A +       L  EDIV   +P  K ++T  +       
Sbjct: 1369 IDCSARDYQDRLTNARYAIGLARKIGAGVYAL-PEDIV-EVKP--KMLLTVFACLMMRDF 1536

Query: 251  GAQKAETAAN------RICKVLAVNQE 271
             ++ A   AN       +C+ L VN E
Sbjct: 1537 SSRPAAAEANSH*VWDNVCE*LGVNTE 1617

 Score = 37.4 bits (85), Expect = 0.028,   Method: Compositional matrix adjust.
 Identities = 35/137 (25%), Positives = 55/137 (40%), Gaps = 17/137 (12%)
 Frame = +1

Query: 33  QRKTFTAWCNSHLRKA------------GTQIENIEEDFRDGLKLMLLLE-----VISGE 75
           ++K F  W N HL               GTQ+        DG+ L  L+       I   
Sbjct: 52  EQKAFAEWINRHLSDXPDCKHLLPLDADGTQLFG---QMADGVLLCKLINHSVSNTIDER 222

Query: 76  RLAKPERGKMRVHKISNVNKALDFIASKGVKLVSIGAEEIVDGNVKMTLGMIWTIILRFA 135
            + K      R H+  N+  A++   + G   V+IG E++  G   + LG++W II    
Sbjct: 223 TINKQNLSLYRRHE--NLTLAVNSAGAIGCTTVNIGPEDLAAGRPHLVLGLLWQIIRIGL 396

Query: 136 IQDISVEETSAKEGLLL 152
           + DI++        LLL
Sbjct: 397 LSDINLAHHPGLVNLLL 447
>18556
          Length = 799

 Score = 48.1 bits (113), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 30/104 (28%), Positives = 48/104 (46%), Gaps = 1/104 (0%)
 Frame = +2

Query: 149 GLLLWCQRKTAPYK-NVNIQNFHISWKDGLGFCALIHRHRPELIDYGKLRKDDPLTNLNT 207
            LL W   + A Y+    ++     +++G   CALI R RP+LIDY   +   PL     
Sbjct: 44  SLLRWISVQLAAYQFTAELKEPSDVFRNGRVLCALISRFRPDLIDYAATKDMSPLECNEL 223

Query: 208 AFDVAERFLDIPKMLDAEDIVGTARPDEKAIMTYVSSFYHAFSG 251
           AF V ER L I +++ A+  +     + +  + Y+      F G
Sbjct: 224 AFAVLERELHIDRIMSAKQSLDLNDVESRVWLNYMDQICELFRG 355
>38338
          Length = 463

 Score = 40.0 bits (92), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 23/70 (32%), Positives = 40/70 (57%)
 Frame = -2

Query: 740 AKGISQEQMNEFRASFNHFDRDHSGTLGPEEFKACLISLGYDIGNDPQGEAEFARIMSIV 799
           A  +++EQ+ EF+ +F+ FD+D  GT+  +E    + SL    G +P  EAE   +++ V
Sbjct: 195 ADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSL----GQNPT-EAELQDMINEV 31

Query: 800 DPNRLGVVTF 809
           D +  G + F
Sbjct: 30  DADGNGTIDF 1
>32088
          Length = 1928

 Score = 39.7 bits (91), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 29/121 (23%), Positives = 56/121 (46%), Gaps = 12/121 (9%)
 Frame = +1

Query: 33   QRKTFTAWCNSHLR---------KAGTQIENIEEDFRDGLKLMLLLEVISGERLAKPERG 83
            ++K F AW N HL+         +   + +++ +   DG+ L  L+       + +    
Sbjct: 1264 EQKAFAAWINRHLKDDPDCKHLMEVNEEGDDLFKKVGDGILLCKLINHSVSNTIDERAIN 1443

Query: 84   KMRV---HKISNVNKALDFIASKGVKLVSIGAEEIVDGNVKMTLGMIWTIILRFAIQDIS 140
            K  +   H+  N+  A++   S G   V+IG E++  G   + LG++W II    + DI+
Sbjct: 1444 KSNLNVYHRHENLTLAVNSAGSIGCTTVNIGPEDLAAGRPHLVLGLLWQIIRIGLLSDIN 1623

Query: 141  V 141
            +
Sbjct: 1624 L 1626
>28965
          Length = 421

 Score = 39.3 bits (90), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 35/118 (29%), Positives = 53/118 (44%), Gaps = 2/118 (1%)
 Frame = +2

Query: 336 INFNTLQTKLRLSNRPAFMPSEGRMVSDINNAWGCLEQAEKGYEEWLLNEIRRLERL--D 393
           +  NTL  +L     P       +   ++N AW  L Q            + R ERL   
Sbjct: 35  VEVNTLAEQLVTDGHPEEETIRQKQ-EEVNEAWKRLRQLS----------LLRQERLYGA 181

Query: 394 HLAEKFRQKASIHEAWTDGKEAMLRQKDYETATLSEIKALLKKHEAFESDLAAHQDRV 451
           H  ++F + A    AW   K+A+L   DY    L+ ++ L +KHE  E DLAA +++V
Sbjct: 182 HEIQRFNRDADETIAWIQEKDAVLSTDDY-GRDLASVQTLQRKHEGVERDLAALEEKV 352
>04951
          Length = 2852

 Score = 38.9 bits (89), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 44/173 (25%), Positives = 76/173 (43%), Gaps = 16/173 (9%)
 Frame = +1

Query: 105 VKLVSIGAEEIVDGNVKMTLGMIWTIILRFAIQDISVEETSAK----EGLLLWCQRKTAP 160
           +KLV IG ++I DGN  +TLG++W ++  + +  +S      K      ++ W   K   
Sbjct: 61  MKLVGIGGKDIHDGNPVLTLGLVWQLMRAYTLAILSKLTEDKKPIQDSEIVDWVNSKVK- 237

Query: 161 YKNVNIQNFHIS-WKDGLGFCALIHRHRPELIDYGKLR-----KDDPLTNLNTAFDVAER 214
            K+  I +F  S   DG+    +I   +P ++++  +       DD L N   A  +A +
Sbjct: 238 -KDERIGSFQDSKLNDGVIVAKVIESIKPGIVNWENINPNASEPDDRLANARYAIGLARK 414

Query: 215 FLDIPKMLDAEDIVGTARPDEKAIMTYVSSFY------HAFSGAQKAETAANR 261
                  L  EDIV   +P  K ++T  +         H  +   +  TAAN+
Sbjct: 415 IGAGVYAL-PEDIV-EVKP--KMLLTVFACLMMRDLSAHKATQGVRGPTAANK 561
>20251
          Length = 2203

 Score = 37.7 bits (86), Expect = 0.023,   Method: Compositional matrix adjust.
 Identities = 41/155 (26%), Positives = 62/155 (40%), Gaps = 8/155 (5%)
 Frame = +3

Query: 743 ISQEQMNEFRASFNHFDRDHSGTLGPEEFKACLISLGYDIGNDPQGEAEFARIMSIVDPN 802
             Q Q+ EF+ +FN  D++  G +  E+    L SL    G +P  E +   +M+     
Sbjct: 141 FDQSQIQEFKEAFNMIDQNRDGFIDKEDLGDMLASL----GKNPT-EGQLDEMMNXAP-- 299

Query: 803 RLGVVTFQAFIDFMSRETADTDTADQVMASFKILAGD-KNYITEDELRRELPPDQAEYC- 860
             G + F  F+     +   TD  D +  +F     D K  I ED LR  L      +  
Sbjct: 300 --GPINFTMFLTMFGDKLNGTDPEDVIKNAFACFDEDGKGVIQEDRLRELLTTMGDRFTD 473

Query: 861 -----IARMAPYAGPDSVPGALDYMSFSTAL-YGE 889
                + R AP        G  DY+ F+  L YG+
Sbjct: 474 DEVDEMFRDAPIK-----RGNFDYLEFTRILKYGK 563
>38533
          Length = 380

 Score = 37.4 bits (85), Expect = 0.028,   Method: Compositional matrix adjust.
 Identities = 14/50 (28%), Positives = 32/50 (64%)
 Frame = +1

Query: 426 TLSEIKALLKKHEAFESDLAAHQDRVEQIAAIAQELNELDYYDSPSVNAR 475
           +L+ ++ L+KKH+A ES++ AH+  ++ +A  AQ++    ++ +  +  R
Sbjct: 70  SLTAVQNLMKKHQALESEIVAHEPLIDAVATSAQQMIRTKHFATADIQTR 219
>03732
          Length = 1114

 Score = 32.0 bits (71), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 31/119 (26%), Positives = 51/119 (42%)
 Frame = -1

Query: 695  IQEALIFDNKHTNYNMEHIRVGWEQLLTTIARTINEVENQILTRDAKGISQEQMNEFRAS 754
            +Q+AL  +   T +N E +R+         + TIN  E Q L +         + +++  
Sbjct: 1036 LQQALS-NGTWTPFNPETVRLMIGMFDRDNSGTINFQEFQALWK--------YVTDWQNC 884

Query: 755  FNHFDRDHSGTLGPEEFKACLISLGYDIGNDPQGEAEFARIMSIVDPNRLGVVTFQAFI 813
            F  +DRD+SG++   E K  L   GY +      +  F  ++   D    G V F  FI
Sbjct: 883  FRSYDRDNSGSIDRNELKNALTGFGYRL-----SDRFFDVLVKKFDRQGKGTVAFDDFI 722
>14027
          Length = 958

 Score = 29.6 bits (65), Expect = 4.9,   Method: Compositional matrix adjust.
 Identities = 17/43 (39%), Positives = 23/43 (53%), Gaps = 2/43 (4%)
 Frame = -1

Query: 26  DPAWEKQQRKTFTAWCN--SHLRKAGTQIENIEEDFRDGLKLM 66
           +  W KQ +   TA+CN   H+      IENIE+DF+    LM
Sbjct: 514 NXVWSKQTKSDITAFCNYCCHI------IENIEKDFKVQKXLM 404
>30240
          Length = 346

 Score = 29.6 bits (65), Expect = 5.4,   Method: Composition-based stats.
 Identities = 12/37 (32%), Positives = 20/37 (54%)
 Frame = +2

Query: 8  QTNDYMQPEEDWDRDLLLDPAWEKQQRKTFTAWCNSH 44
           T+ Y++      +D+L+ P  +K  R+ F  WCN H
Sbjct: 47 HTHTYIRTNTHQIQDILMSPE-KKTHRRKFVLWCNQH 154
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|94374305|ref|XP_001000876.1| PREDICTED: membrane
associated guanylate kinase, WW and PDZ domain containing 2 isoform 2
[Mus musculus]
         (1414 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

03499                                                                 279   6e-75
26162                                                                  58   2e-08
20073                                                                  55   2e-07
03831                                                                  48   3e-05
29974                                                                  44   6e-04
28454                                                                  42   0.002
38751                                                                  40   0.005
33791                                                                  38   0.022
27345                                                                  37   0.039
25750                                                                  37   0.040
29705                                                                  37   0.041
37239                                                                  37   0.060
02951                                                                  35   0.15 
37652                                                                  34   0.44 
08480                                                                  32   1.3  
01502                                                                  32   1.7  
39267                                                                  32   1.7  
33158                                                                  32   2.2  
17402                                                                  31   2.9  
08444                                                                  30   8.9  
>03499
          Length = 1247

 Score =  279 bits (713), Expect = 6e-75,   Method: Compositional matrix adjust.
 Identities = 172/432 (39%), Positives = 245/432 (56%), Gaps = 42/432 (9%)
 Frame = -3

Query: 355  KIDDPIYGTYYVDHINRRTQFENPV------------------------LEAKRKLQQHN 390
            K++DP YGTYY+DH+NRRTQ+ENPV                        L ++R +  ++
Sbjct: 1245 KVEDPHYGTYYIDHVNRRTQYENPVSTVKKEEGEEMNGTGTYPPLLKPDLSSQRSVSDNS 1066

Query: 391  MP-HTELGAKPLQAPGFREKPLFTRDASQLKGTFLSTTLKKSNMGFGFTIIGGDEPD-EF 448
            M  +   G++P       +KP FT+   +L+G F+ T+L KS  GFGFTI+G D PD EF
Sbjct: 1065 MNININGGSRPDW-----KKPFFTKQPGELQGEFVKTSLVKSVRGFGFTIVGSDHPDTEF 901

Query: 449  LQVKSVIPDGPAAQDGKMETGDVIVYINEVCVLGHTHADVVKLFQSVPIGQSVNLVLCRG 508
            LQ+K+V+P+GPA  +GK++TGDVIV++N  CVLG+TH DVV LFQ++  G++V L +CRG
Sbjct: 900  LQIKNVVPNGPAYLNGKLKTGDVIVFVNTTCVLGYTHQDVVSLFQTISPGETVTLEICRG 721

Query: 509  YPLPFDPEDPANSMVPPLAI--------MERPPPVMVNGRHNYETYLEYISRTSQSVPDI 560
            YPL FDP+DP   +V  LA+         E  P   + G       L   +R+ +S+PD+
Sbjct: 720  YPLHFDPDDPNTEIVTTLAVNMPQDGHSSESAPFSTLGGSD-----LNSSNRSLKSLPDL 556

Query: 561  T------DRPPHSLHSMPADGQ--LDGTYPPPVHDDNVSMASSGATQAELMTLTIVKGAQ 612
                        S HSMP D +    G  PP    D V++ S    + E++++ IV+G  
Sbjct: 555  ARSANVHSNMSFSQHSMPGDLKSLSQGNGPP----DLVTVTS----KPEILSINIVRGQM 400

Query: 613  GFGFTIADSPTGQRVKQILDIQGCPGLCEGDLIVEINQQNVQNLSHTEVVDILKDCPVGS 672
            GFGFTIADSP GQ+VKQILD   C  L E DL+ EIN+ +V+ ++H ++V +LKDCP+G 
Sbjct: 399  GFGFTIADSPYGQKVKQILDKGRCKTLQENDLLQEINRVDVKRMTHAQIVQVLKDCPIGV 220

Query: 673  ETSLIIHRGGFFSPWKTPKPMMDRWENQGSPQTSLSAPAVPQNLPFPPALHRSSFPDSTE 732
            +T +I+ RGG   P  + K M        + Q+    P V  NL  P A   +    +  
Sbjct: 219  DTQIIVQRGGI--PLHSKKKMK-------TSQSFDDRPPV-NNLNAPGAYFFTGSDSNLR 70

Query: 733  AFDPRKPDPYEL 744
              DP  PD  E+
Sbjct: 69   NADPSLPDGDEI 34

 Score = 58.9 bits (141), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 63/259 (24%), Positives = 106/259 (40%), Gaps = 30/259 (11%)
 Frame = -3

Query: 780  LRRMESGFGFRILGGDEPGQPIL-IGAVIAMGSADRDGRLHPGDELVYVDGIPVAGKTHR 838
            L +   GFGF I+G D P    L I  V+  G A  +G+L  GD +V+V+   V G TH+
Sbjct: 966  LVKSVRGFGFTIVGSDHPDTEFLQIKNVVPNGPAYLNGKLKTGDVIVFVNTTCVLGYTHQ 787

Query: 839  YVIDLMHHAARNGQVNLTVRRKVLCGGEPCPENGRSPGSVSTH-----HSSPRSDYATYX 893
             V+ L    +    V L + R      +P   N     +++ +     HSS  + ++T  
Sbjct: 786  DVVSLFQTISPGETVTLEICRGYPLHFDPDDPNTEIVTTLAVNMPQDGHSSESAPFSTLG 607

Query: 894  XXXXXXXXXXXXXXEGFASHSLQTSDVVIHRKE--------NEGFG---FVIISS----- 937
                             A  +   S++   +          ++G G    V ++S     
Sbjct: 606  GSDLNSSNRSLKSLPDLARSANVHSNMSFSQHSMPGDLKSLSQGNGPPDLVTVTSKPEIL 427

Query: 938  ---LNRPESGATITVP-----HKIGRIIDGSPADRCAKLKVGDRILAVNGQSIINMPHAD 989
               + R + G   T+       K+ +I+D     RC  L+  D +  +N   +  M HA 
Sbjct: 426  SINIVRGQMGFGFTIADSPYGQKVKQILD---KGRCKTLQENDLLQEINRVDVKRMTHAQ 256

Query: 990  IVKLIKDAGLSVTLRIIPQ 1008
            IV+++KD  + V  +II Q
Sbjct: 255  IVQVLKDCPIGVDTQIIVQ 199

 Score = 43.9 bits (102), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 22/82 (26%), Positives = 41/82 (50%), Gaps = 3/82 (3%)
 Frame = -3

Query: 1130 RQPQDF--DYFTVDMEKGAKGFGFSIRGGREYKMD-LYVLRLAEDGPAIRNGRMRVGDQI 1186
            +QP +   ++    + K  +GFGF+I G      + L +  +  +GPA  NG+++ GD I
Sbjct: 1008 KQPGELQGEFVKTSLVKSVRGFGFTIVGSDHPDTEFLQIKNVVPNGPAYLNGKLKTGDVI 829

Query: 1187 IEINGESTRDMTHARAIELIKS 1208
            + +N       TH   + L ++
Sbjct: 828  VFVNTTCVLGYTHQDVVSLFQT 763

 Score = 43.1 bits (100), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 67/290 (23%), Positives = 115/290 (39%), Gaps = 7/290 (2%)
 Frame = -3

Query: 925  KENEGFGFVIISSLNRPESGATITVPHKIGRIIDGSPADRCAKLKVGDRILAVNGQSIIN 984
            K   GFGF I+ S + P++        +I  ++   PA    KLK GD I+ VN   ++ 
Sbjct: 960  KSVRGFGFTIVGS-DHPDTEFL-----QIKNVVPNGPAYLNGKLKTGDVIVFVNTTCVLG 799

Query: 985  MPHADIVKLIKDA--GLSVTLRIIPQEELNSPTSAPSSEKQSPMAQQHSPLAQQSPLAQP 1042
              H D+V L +    G +VTL I     L+     P++E  + +A  + P    S  + P
Sbjct: 798  YTHQDVVSLFQTISPGETVTLEICRGYPLHFDPDDPNTEIVTTLA-VNMPQDGHSSESAP 622

Query: 1043 SPATPNSPVXXXXXXXXXXXXGHENSYRSEVKARQDVKPDIRQPPFTDYRQ--PPLDYRQ 1100
                  S +               NS    +K+  D+           + Q   P D + 
Sbjct: 621  FSTLGGSDL---------------NSSNRSLKSLPDLARSANVHSNMSFSQHSMPGDLKS 487

Query: 1101 PPGGDYSQPPPLDYRQHSPDTRQYPLSDYRQPQDFDYFTVDMEKGAKGFGFSIRG---GR 1157
               G+   PP L      P                +  ++++ +G  GFGF+I     G+
Sbjct: 486  LSQGN--GPPDLVTVTSKP----------------EILSINIVRGQMGFGFTIADSPYGQ 361

Query: 1158 EYKMDLYVLRLAEDGPAIRNGRMRVGDQIIEINGESTRDMTHARAIELIK 1207
            + K      ++ + G   R   ++  D + EIN    + MTHA+ ++++K
Sbjct: 360  KVK------QILDKG---RCKTLQENDLLQEINRVDVKRMTHAQIVQVLK 238
>26162
          Length = 608

 Score = 58.2 bits (139), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 31/80 (38%), Positives = 40/80 (50%)
 Frame = +1

Query: 302 PLPDNWEMAYTEKGEVYFIDHNTKTTSWLDPRLXXXXXXXXXXXXXXLPYGWEKIDDPIY 361
           PLP+ WE     +G  YF+DHNT+TT+W  P+               LP GWE+  D   
Sbjct: 79  PLPNGWEARKDSQGRTYFVDHNTRTTTWERPQ--------------PLPAGWERRIDQHG 216

Query: 362 GTYYVDHINRRTQFENPVLE 381
             YYVDH  R T ++ P  E
Sbjct: 217 RVYYVDHNTRTTTWQRPNTE 276

 Score = 49.7 bits (117), Expect = 8e-06,   Method: Compositional matrix adjust.
 Identities = 31/105 (29%), Positives = 40/105 (38%), Gaps = 28/105 (26%)
 Frame = +1

Query: 302 PLPDNWEMAYTEKGEVYFIDHNTKTTSWLDPRLXXXXXXXXXXXXXX------------- 348
           PLP  WE    + G VY++DHNT+TT+W  P                             
Sbjct: 175 PLPAGWERRIDQHGRVYYVDHNTRTTTWQRPNTEMVTNWNNWQQWRNNRTMDAMNQRFLF 354

Query: 349 ---------------LPYGWEKIDDPIYGTYYVDHINRRTQFENP 378
                          L  GWEK  D     Y+V+H NR TQ+E+P
Sbjct: 355 PQTAQPSVDNDPLGPLLDGWEKRTDATGRVYFVNHKNRTTQWEDP 489

 Score = 44.7 bits (104), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 18/31 (58%), Positives = 25/31 (80%)
 Frame = +1

Query: 301 DPLPDNWEMAYTEKGEVYFIDHNTKTTSWLD 331
           DPL + WEM YT++G  YF+DHNT+TT++ D
Sbjct: 514 DPLQEGWEMRYTQEGVRYFVDHNTRTTTFQD 606

 Score = 44.3 bits (103), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 28/82 (34%), Positives = 36/82 (43%)
 Frame = +1

Query: 296 ENEDSDPLPDNWEMAYTEKGEVYFIDHNTKTTSWLDPRLXXXXXXXXXXXXXXLPYGWEK 355
           +N+   PL D WE      G VYF++H  +TT W DPR               L  GWE 
Sbjct: 379 DNDPLGPLLDGWEKRTDATGRVYFVNHKNRTTQWEDPRT------QGVMQEDPLQEGWEM 540

Query: 356 IDDPIYGTYYVDHINRRTQFEN 377
                   Y+VDH  R T F++
Sbjct: 541 RYTQEGVRYFVDHNTRTTTFQD 606
>20073
          Length = 582

 Score = 55.1 bits (131), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 30/73 (41%), Positives = 41/73 (56%)
 Frame = +3

Query: 786 GFGFRILGGDEPGQPILIGAVIAMGSADRDGRLHPGDELVYVDGIPVAGKTHRYVIDLMH 845
           G GF ++GG E   PI I  +I  G ADR   L  GD+L+ V+G+ V G+ H   ++L+ 
Sbjct: 3   GLGFNVMGGKEQSSPIYISRIIPGGVADRLNCLKRGDQLLSVNGVSVEGEYHEKAVELLK 182

Query: 846 HAARNGQVNLTVR 858
            A   G V L VR
Sbjct: 183 LA--QGSVRLVVR 215

 Score = 47.4 bits (111), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 22/60 (36%), Positives = 36/60 (60%)
 Frame = +3

Query: 1148 GFGFSIRGGREYKMDLYVLRLAEDGPAIRNGRMRVGDQIIEINGESTRDMTHARAIELIK 1207
            G GF++ GG+E    +Y+ R+   G A R   ++ GDQ++ +NG S     H +A+EL+K
Sbjct: 3    GLGFNVMGGKEQSSPIYISRIIPGGVADRLNCLKRGDQLLSVNGVSVEGEYHEKAVELLK 182

 Score = 41.6 bits (96), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 29/61 (47%), Positives = 35/61 (57%), Gaps = 2/61 (3%)
 Frame = +3

Query: 950  PHKIGRIIDGSPADRCAKLKVGDRILAVNGQSIINMPHADIVKLIKDAGLSVTL--RIIP 1007
            P  I RII G  ADR   LK GD++L+VNG S+    H   V+L+K A  SV L  R  P
Sbjct: 45   PIYISRIIPGGVADRLNCLKRGDQLLSVNGVSVEGEYHEKAVELLKLAQGSVRLVVRYTP 224

Query: 1008 Q 1008
            Q
Sbjct: 225  Q 227

 Score = 39.3 bits (90), Expect = 0.011,   Method: Compositional matrix adjust.
 Identities = 19/60 (31%), Positives = 32/60 (53%)
 Frame = +3

Query: 434 GFGFTIIGGDEPDEFLQVKSVIPDGPAAQDGKMETGDVIVYINEVCVLGHTHADVVKLFQ 493
           G GF ++GG E    + +  +IP G A +   ++ GD ++ +N V V G  H   V+L +
Sbjct: 3   GLGFNVMGGKEQSSPIYISRIIPGGVADRLNCLKRGDQLLSVNGVSVEGEYHEKAVELLK 182
>03831
          Length = 1143

 Score = 48.1 bits (113), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 26/57 (45%), Positives = 35/57 (61%)
 Frame = +3

Query: 953  IGRIIDGSPADRCAKLKVGDRILAVNGQSIINMPHADIVKLIKDAGLSVTLRIIPQE 1009
            IG++ +GSPA+  A LK GDRI+ VNG +I N  H  +V  IK  G    L ++ QE
Sbjct: 216  IGKVDEGSPAE-AAGLKAGDRIVEVNGTNIGNENHQQVVGRIKAGGDETRLLVVDQE 383

 Score = 38.5 bits (88), Expect = 0.021,   Method: Compositional matrix adjust.
 Identities = 23/79 (29%), Positives = 41/79 (51%)
 Frame = +3

Query: 928  EGFGFVIISSLNRPESGATITVPHKIGRIIDGSPADRCAKLKVGDRILAVNGQSIINMPH 987
            +G+GF + +  ++P           IG +   SPA+    LK GDRI+ VNG++I    H
Sbjct: 612  DGYGFNLHAEKDKP--------GQYIGSVDPNSPAE-TGGLKEGDRIIEVNGENIETTNH 764

Query: 988  ADIVKLIKDAGLSVTLRII 1006
              +++ IK  G   ++ ++
Sbjct: 765  TAVIQNIKSRGDKTSMLVV 821

 Score = 36.6 bits (83), Expect = 0.070,   Method: Compositional matrix adjust.
 Identities = 21/61 (34%), Positives = 35/61 (57%)
 Frame = +3

Query: 1148 GFGFSIRGGREYKMDLYVLRLAEDGPAIRNGRMRVGDQIIEINGESTRDMTHARAIELIK 1207
            G+GF++   ++ K   Y+  +  + PA   G ++ GD+IIE+NGE+     H   I+ IK
Sbjct: 615  GYGFNLHAEKD-KPGQYIGSVDPNSPA-ETGGLKEGDRIIEVNGENIETTNHTAVIQNIK 788

Query: 1208 S 1208
            S
Sbjct: 789  S 791

 Score = 36.2 bits (82), Expect = 0.100,   Method: Compositional matrix adjust.
 Identities = 16/41 (39%), Positives = 28/41 (68%)
 Frame = +3

Query: 638 GLCEGDLIVEINQQNVQNLSHTEVVDILKDCPVGSETSLII 678
           GL EGD I+E+N +N++  +HT V+  +K    G +TS+++
Sbjct: 702 GLKEGDRIIEVNGENIETTNHTAVIQNIK--SRGDKTSMLV 818

 Score = 32.7 bits (73), Expect = 1.0,   Method: Compositional matrix adjust.
 Identities = 17/61 (27%), Positives = 35/61 (57%)
 Frame = +3

Query: 1148 GFGFSIRGGREYKMDLYVLRLAEDGPAIRNGRMRVGDQIIEINGESTRDMTHARAIELIK 1207
            G+GF++    + K   ++ ++ E  PA   G ++ GD+I+E+NG +  +  H + +  IK
Sbjct: 168  GYGFNLHA-EKGKAGQFIGKVDEGSPAEAAG-LKAGDRIVEVNGTNIGNENHQQVVGRIK 341

Query: 1208 S 1208
            +
Sbjct: 342  A 344
>29974
          Length = 344

 Score = 43.5 bits (101), Expect = 6e-04,   Method: Compositional matrix adjust.
 Identities = 21/50 (42%), Positives = 30/50 (60%), Gaps = 1/50 (2%)
 Frame = +1

Query: 137 TVPCTTRPHKEGEVPGVDYIFITVEEFMELE-KSGALLESGTYEDNYYGT 185
            +P TTR  +  E PG DY F++  E ME + ++   +E+G Y DN YGT
Sbjct: 43  CIPHTTRERRTNEEPGQDYHFVSSREQMERDIQNHLFIEAGVYNDNLYGT 192
>28454
          Length = 472

 Score = 41.6 bits (96), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 14/34 (41%), Positives = 21/34 (61%)
 Frame = -2

Query: 301 DPLPDNWEMAYTEKGEVYFIDHNTKTTSWLDPRL 334
           DPLP  WE      G +++IDH  +TT+W  P++
Sbjct: 309 DPLPSGWEARVDSHGRIFYIDHMNRTTTWQRPQV 208

 Score = 33.5 bits (75), Expect = 0.64,   Method: Compositional matrix adjust.
 Identities = 13/32 (40%), Positives = 19/32 (59%)
 Frame = -2

Query: 349 LPYGWEKIDDPIYGTYYVDHINRRTQFENPVL 380
           LP GWE   D     +Y+DH+NR T ++ P +
Sbjct: 303 LPSGWEARVDSHGRIFYIDHMNRTTTWQRPQV 208
>38751
          Length = 329

 Score = 40.4 bits (93), Expect = 0.005,   Method: Composition-based stats.
 Identities = 18/56 (32%), Positives = 35/56 (62%)
 Frame = +3

Query: 1153 IRGGREYKMDLYVLRLAEDGPAIRNGRMRVGDQIIEINGESTRDMTHARAIELIKS 1208
            I+GG+EY   + V  + E   A + G + +GD+I+++NG     +THA A+ ++++
Sbjct: 9    IKGGKEYGTPIVVYVIEEGCQAEQQG-LNIGDRILDVNGTDFTHLTHAEAVTIMRN 173

 Score = 33.5 bits (75), Expect = 0.61,   Method: Composition-based stats.
 Identities = 17/46 (36%), Positives = 29/46 (63%)
 Frame = +3

Query: 968  LKVGDRILAVNGQSIINMPHADIVKLIKDAGLSVTLRIIPQEELNS 1013
            L +GDRIL VNG    ++ HA+ V ++++A  +V + + P  E +S
Sbjct: 87   LNIGDRILDVNGTDFTHLTHAEAVTIMRNA-WNVIMTVQPCPESDS 221
>33791
          Length = 247

 Score = 38.1 bits (87), Expect = 0.022,   Method: Compositional matrix adjust.
 Identities = 21/40 (52%), Positives = 29/40 (72%)
 Frame = +3

Query: 919 DVVIHRKENEGFGFVIISSLNRPESGATITVPHKIGRIID 958
           +V + R+E EGFGFVIISS+ +  SG+T+     IGRII+
Sbjct: 135 EVTVTRRETEGFGFVIISSVTK--SGSTLG--EFIGRIIE 242
>27345
          Length = 496

 Score = 37.4 bits (85), Expect = 0.039,   Method: Compositional matrix adjust.
 Identities = 21/67 (31%), Positives = 35/67 (52%), Gaps = 1/67 (1%)
 Frame = +3

Query: 794 GDEPGQ-PILIGAVIAMGSADRDGRLHPGDELVYVDGIPVAGKTHRYVIDLMHHAARNGQ 852
           G  PG+  I I  +   G+A +DGR+   D+++ VDG  + G T  Y   ++ + +  GQ
Sbjct: 3   GCRPGKLGIFIKTLTDGGAAQKDGRIQVNDQIIEVDGKSLVGVTQAYAASVLRNTS--GQ 176

Query: 853 VNLTVRR 859
           V   + R
Sbjct: 177 VTFHIGR 197
>25750
          Length = 428

 Score = 37.4 bits (85), Expect = 0.040,   Method: Compositional matrix adjust.
 Identities = 18/59 (30%), Positives = 29/59 (49%), Gaps = 2/59 (3%)
 Frame = +3

Query: 299 DSDPLPDNWEMAYTEKGEVYFIDHNTKTTSWLDPRLXXXXXXXXXXXXXXLP--YGWEK 355
           D   LPD +E   T++G++YF+   T  ++W DPR+               P  +GWE+
Sbjct: 252 DMMELPDGYEQRRTQQGQIYFLHTRTGVSTWHDPRVPREASNLELRDEDLGPMLHGWER 428
>29705
          Length = 674

 Score = 37.4 bits (85), Expect = 0.041,   Method: Compositional matrix adjust.
 Identities = 18/53 (33%), Positives = 32/53 (60%)
 Frame = -1

Query: 953  IGRIIDGSPADRCAKLKVGDRILAVNGQSIINMPHADIVKLIKDAGLSVTLRI 1005
            I ++I+G  A++  ++ V DR+LAVN  ++ ++ H + V  +K  G  V L I
Sbjct: 353  ITKVIEGGSAEQDGRIAVMDRLLAVNEHNLEDVTHEEAVAALKSTGDVVRLTI 195

 Score = 31.2 bits (69), Expect = 2.9,   Method: Composition-based stats.
 Identities = 12/36 (33%), Positives = 22/36 (61%)
 Frame = -2

Query: 1172 GPAIRNGRMRVGDQIIEINGESTRDMTHARAIELIK 1207
            G A  +GR+R+ D I+++  E   + TH  A++ +K
Sbjct: 619  GAAAEDGRLRLNDIIVKVGTEDVSNTTHTAAVDALK 512

 Score = 30.4 bits (67), Expect = 5.5,   Method: Compositional matrix adjust.
 Identities = 18/62 (29%), Positives = 30/62 (48%)
 Frame = -1

Query: 446 DEFLQVKSVIPDGPAAQDGKMETGDVIVYINEVCVLGHTHADVVKLFQSVPIGQSVNLVL 505
           D  + +  VI  G A QDG++   D ++ +NE  +   TH + V   +S   G  V L +
Sbjct: 368 DNGIFITKVIEGGSAEQDGRIAVMDRLLAVNEHNLEDVTHEEAVAALKST--GDVVRLTI 195

Query: 506 CR 507
            +
Sbjct: 194 AK 189
>37239
          Length = 453

 Score = 37.0 bits (84), Expect = 0.060,   Method: Compositional matrix adjust.
 Identities = 16/38 (42%), Positives = 23/38 (60%)
 Frame = -2

Query: 1171 DGPAIRNGRMRVGDQIIEINGESTRDMTHARAIELIKS 1208
            D PA R+ R+ VGD+++EING       H  A  ++KS
Sbjct: 446  DSPAARDARIHVGDELLEINGNLLHGRCHLNASAIVKS 333

 Score = 33.5 bits (75), Expect = 0.58,   Method: Compositional matrix adjust.
 Identities = 18/52 (34%), Positives = 28/52 (53%)
 Frame = -2

Query: 456 PDGPAAQDGKMETGDVIVYINEVCVLGHTHADVVKLFQSVPIGQSVNLVLCR 507
           PD PAA+D ++  GD ++ IN   + G  H +   + +SV     V LV+ R
Sbjct: 449 PDSPAARDARIHVGDELLEINGNLLHGRCHLNASAIVKSV-TAPDVKLVVNR 297
>02951
          Length = 1076

 Score = 35.4 bits (80), Expect = 0.15,   Method: Compositional matrix adjust.
 Identities = 16/46 (34%), Positives = 31/46 (67%)
 Frame = +2

Query: 1163 LYVLRLAEDGPAIRNGRMRVGDQIIEINGESTRDMTHARAIELIKS 1208
            +YV  + E+ PA R G +++ D+I+++NG+    +TH +A+E I+ 
Sbjct: 23   IYVTFIYENSPAARCG-LQLHDKILQLNGKDFTVVTHKQAVENIRK 157
>37652
          Length = 229

 Score = 33.9 bits (76), Expect = 0.44,   Method: Compositional matrix adjust.
 Identities = 13/34 (38%), Positives = 21/34 (61%)
 Frame = -3

Query: 299 DSDPLPDNWEMAYTEKGEVYFIDHNTKTTSWLDP 332
           D + LP+ WE   +  G V++++H T+TT W  P
Sbjct: 107 DPNELPEGWEERRSASGRVHYVNHVTRTTQWETP 6

 Score = 30.8 bits (68), Expect = 3.7,   Method: Compositional matrix adjust.
 Identities = 13/30 (43%), Positives = 18/30 (60%)
 Frame = -3

Query: 349 LPYGWEKIDDPIYGTYYVDHINRRTQFENP 378
           LP GWE+        +YV+H+ R TQ+E P
Sbjct: 95  LPEGWEERRSASGRVHYVNHVTRTTQWETP 6
>08480
          Length = 698

 Score = 32.3 bits (72), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 18/48 (37%), Positives = 25/48 (52%)
 Frame = -1

Query: 961  PADRCAKLKVGDRILAVNGQSIINMPHADIVKLIKDAGLSVTLRIIPQ 1008
            PAD    L+ GD+IL+VN   +    H    + +K AG   T+ II Q
Sbjct: 695  PADLSGDLRRGDKILSVNDVDVERATHEQAAQALKRAG--DTVEIIAQ 558
>01502
          Length = 1949

 Score = 32.0 bits (71), Expect = 1.7,   Method: Composition-based stats.
 Identities = 16/45 (35%), Positives = 31/45 (68%)
 Frame = +1

Query: 1163 LYVLRLAEDGPAIRNGRMRVGDQIIEINGESTRDMTHARAIELIK 1207
            +YV  + E+ PA R G +++ D+I+++NG+    +TH +A+E I+
Sbjct: 37   IYVTFIYENSPAARCG-LQLHDKILQLNGKDFTVVTHKQAVENIR 168
>39267
          Length = 456

 Score = 32.0 bits (71), Expect = 1.7,   Method: Compositional matrix adjust.
 Identities = 16/42 (38%), Positives = 25/42 (59%)
 Frame = +1

Query: 1148 GFGFSIRGGREYKMDLYVLRLAEDGPAIRNGRMRVGDQIIEI 1189
            G GF+I G    +  +YV +L   GPA  +G++ VGD+I  +
Sbjct: 115  GLGFNISG--NMRDGIYVSQLHNRGPASESGKIHVGDRIQSV 234
>33158
          Length = 1075

 Score = 31.6 bits (70), Expect = 2.2,   Method: Compositional matrix adjust.
 Identities = 14/47 (29%), Positives = 24/47 (51%)
 Frame = +2

Query: 778 VHLRRMESGFGFRILGGDEPGQPILIGAVIAMGSADRDGRLHPGDEL 824
           +HL +     G  +      G  +LI  ++  G+A++ G LH GDE+
Sbjct: 944 IHLEKTNEHLGATV---KNEGDSVLIARIVKGGAAEKSGLLHEGDEI 1075
>17402
          Length = 488

 Score = 31.2 bits (69), Expect = 2.9,   Method: Composition-based stats.
 Identities = 14/28 (50%), Positives = 19/28 (67%)
 Frame = -2

Query: 643 DLIVEINQQNVQNLSHTEVVDILKDCPV 670
           DLI  IN ++VQ+L HT+VV +L    V
Sbjct: 487 DLITHINDESVQSLLHTQVVHLLSSSTV 404
>08444
          Length = 715

 Score = 29.6 bits (65), Expect = 8.9,   Method: Compositional matrix adjust.
 Identities = 13/31 (41%), Positives = 19/31 (61%)
 Frame = -2

Query: 561 TDRPPHSLHSMPADGQLDGTYPPPVHDDNVS 591
           T RPPH L  +P  GQ++    P  HDD+++
Sbjct: 99  TARPPHHLQLVPMIGQVEVHVRPFTHDDHLA 7
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|70906474|ref|NP_036191.2| Ca<2+>dependent activator
protein for secretion isoform 1 [Mus musculus]
         (1361 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

29674                                                                 278   8e-75
21559                                                                  31   3.3  
>29674
          Length = 488

 Score =  278 bits (712), Expect = 8e-75,   Method: Composition-based stats.
 Identities = 123/162 (75%), Positives = 135/162 (83%)
 Frame = -2

Query: 670 NPCNFDHASLFEMVQRLTLDHRLNDSYSCLGWFSPGQVFVLDEYCARNGVRGCHRHLCYL 729
           +P  + H  LF+++Q LTLD+RL D+Y+CLGWFSPGQVFVLDEYCAR GVRGC RHLCYL
Sbjct: 487 DPYRYSHGDLFKLLQTLTLDYRLGDAYTCLGWFSPGQVFVLDEYCARYGVRGCLRHLCYL 308

Query: 730 RDLLERAENGAMIDPTLLHYSFAFCASHVHGNRPDGIGTVTVXXXXXXXXXXXXLRVLLE 789
            DLLERAE G +IDPTL+HYSFAFCASHVHGN+PDGIGTV              LR+LLE
Sbjct: 307 NDLLERAEKGILIDPTLIHYSFAFCASHVHGNKPDGIGTVLQAERVKFDEIKERLRILLE 128

Query: 790 NQITHFRYCFPFGRPEGALKATLSLLERVLMKDIVTPVPQEE 831
           NQITHFRYCFPFGRPEGALKATLSLLERVLMKDIVTPVP EE
Sbjct: 127 NQITHFRYCFPFGRPEGALKATLSLLERVLMKDIVTPVPPEE 2
>21559
          Length = 521

 Score = 31.2 bits (69), Expect = 3.3,   Method: Composition-based stats.
 Identities = 17/36 (47%), Positives = 17/36 (47%)
 Frame = -1

Query: 522 HSGYLWTIGKNVWKRWKKRFFVLVQVSQYTFAMCSY 557
           H  YL  I KN WK W KRF   V    YTF    Y
Sbjct: 392 HGLYLQRI*KNCWKEW*KRF--AVTCMNYTFGRYLY 291
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31542899|ref|NP_038559.2| guanine nucleotide-binding
protein, beta-4 subunit [Mus musculus]
         (340 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

30295                                                                 276   1e-74
17266                                                                 261   8e-71
14555                                                                  96   6e-35
17598                                                                  96   3e-20
12806                                                                  87   8e-18
34511                                                                  76   9e-16
30256                                                                  80   2e-15
13335                                                                  79   3e-15
27465                                                                  79   4e-15
02147                                                                  76   2e-14
00561                                                                  71   8e-13
19949                                                                  68   5e-12
02960                                                                  66   2e-11
03395                                                                  65   5e-11
17602                                                                  64   8e-11
03387                                                                  60   1e-09
10162                                                                  59   3e-09
01805                                                                  57   1e-08
03156                                                                  54   1e-07
01327                                                                  53   1e-07
02090                                                                  53   1e-07
26107                                                                  53   2e-07
12574                                                                  52   2e-07
19498                                                                  52   3e-07
13278                                                                  50   2e-06
12960                                                                  49   2e-06
21105                                                                  49   4e-06
37180                                                                  47   1e-05
11493                                                                  47   1e-05
01598                                                                  46   2e-05
01249                                                                  45   3e-05
14500                                                                  39   5e-05
10264                                                                  43   2e-04
19863                                                                  43   2e-04
15780                                                                  41   6e-04
01462                                                                  41   7e-04
18981                                                                  41   7e-04
15118                                                                  40   0.001
31864                                                                  40   0.001
16199                                                                  38   0.001
00825                                                                  40   0.001
31384                                                                  39   0.004
34005                                                                  37   0.010
27806                                                                  36   0.019
31054                                                                  35   0.033
29912                                                                  35   0.037
26939                                                                  35   0.052
27270                                                                  34   0.066
04088                                                                  34   0.078
21921                                                                  33   0.14 
33180                                                                  33   0.24 
15972                                                                  32   0.28 
35607                                                                  32   0.30 
18320                                                                  32   0.36 
15337                                                                  31   0.57 
07665                                                                  30   0.97 
11915                                                                  30   1.1  
17298                                                                  30   1.1  
15745                                                                  30   1.5  
07781                                                                  30   1.6  
19140                                                                  30   1.7  
12140                                                                  29   3.3  
20662                                                                  28   3.6  
16477                                                                  28   4.1  
22113                                                                  28   4.5  
27525                                                                  28   4.8  
04358                                                                  28   5.1  
05907                                                                  28   7.6  
27681                                                                  27   8.1  
38177                                                                  27   8.4  
>30295
          Length = 593

 Score =  276 bits (705), Expect = 1e-74,   Method: Compositional matrix adjust.
 Identities = 130/153 (84%), Positives = 139/153 (90%)
 Frame = +2

Query: 18  IQDARKACNDATLVQITSNMDSVGRIQMRTRRTLRGHLAKIYAMHWGYDSRLLVSASQDG 77
           I++ARKA  D TL Q T++ DSVGRIQMRTRRTLR HLAKIYAMHW  DSR LVSASQDG
Sbjct: 134 IREARKAAGDTTLAQATASYDSVGRIQMRTRRTLRXHLAKIYAMHWATDSRNLVSASQDG 313

Query: 78  KLIIWDSYTTNKMHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSR 137
           KLI+WD YTTNK+HAIPLRSSWVMTCAYAPSG YVACGGLDNICSIY+LKTREGNVRVSR
Sbjct: 314 KLIVWDGYTTNKVHAIPLRSSWVMTCAYAPSGGYVACGGLDNICSIYSLKTREGNVRVSR 493

Query: 138 ELPGHTGYLSCCRFLDDGQIITSSGDTTCALWD 170
           ELPGHTGYLSCCRF+DD QI+TSSGD TCALWD
Sbjct: 494 ELPGHTGYLSCCRFIDDNQIVTSSGDMTCALWD 592
>17266
          Length = 480

 Score =  261 bits (666), Expect(2) = 8e-71,   Method: Compositional matrix adjust.
 Identities = 120/147 (81%), Positives = 140/147 (95%)
 Frame = -1

Query: 190 LSLSPDLKTFVSGACDASSKLWDIRDGMCRQSFTGHISDINAVSFFPSGYAFATGSDDAT 249
           LSL+PD++TFVSGACDAS+KLWD+RDGMC+Q+F+GH SDINA+++FP+G+AFATGSDDAT
Sbjct: 441 LSLAPDMRTFVSGACDASAKLWDVRDGMCKQTFSGHESDINAITYFPNGHAFATGSDDAT 262

Query: 250 CRLFDLRADQELLLYSHDNIICGITSVAFSKSGRLLLAGYDDFNCSVWDALKGGRSGVLA 309
           CRLFD+RADQE+ +YSHDNIICGITSVAFSKSGRLLL GYDDFNC++WD LK  R+GVLA
Sbjct: 261 CRLFDIRADQEIGMYSHDNIICGITSVAFSKSGRLLLGGYDDFNCNIWDVLKQERTGVLA 82

Query: 310 GHDNRVSCLGVTDDGMAVATGSWDSFL 336
           GHDNRVSCLGVT+DG AVATGSWDSFL
Sbjct: 81  GHDNRVSCLGVTEDGSAVATGSWDSFL 1

 Score = 24.3 bits (51), Expect(2) = 8e-71,   Method: Compositional matrix adjust.
 Identities = 9/12 (75%), Positives = 12/12 (100%)
 Frame = -3

Query: 178 TTFTGHSGDVMS 189
           T+F+GH+GDVMS
Sbjct: 478 TSFSGHTGDVMS 443

 Score = 30.4 bits (67), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 16/58 (27%), Positives = 31/58 (53%)
 Frame = -1

Query: 283 RLLLAGYDDFNCSVWDALKGGRSGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLRIWN 340
           R  ++G  D +  +WD   G      +GH++ ++ +    +G A ATGS D+  R+++
Sbjct: 420 RTFVSGACDASAKLWDVRDGMCKQTFSGHESDINAITYFPNGHAFATGSDDATCRLFD 247
>14555
          Length = 627

 Score = 96.3 bits (238), Expect(2) = 6e-35,   Method: Compositional matrix adjust.
 Identities = 47/73 (64%), Positives = 55/73 (75%)
 Frame = -2

Query: 218 CRQSFTGHISDINAVSFFPSGYAFATGSDDATCRLFDLRADQELLLYSHDNIICGITSVA 277
           C Q F GH +DIN V F+PSG AFATGSDDATCRLFDLRAD+E+  Y  ++II G  +V 
Sbjct: 623 CVQMFEGHEADINCVRFYPSGDAFATGSDDATCRLFDLRADREVNCYRKESIIFGCNAVD 444

Query: 278 FSKSGRLLLAGYD 290
           FS SGRLL  GY+
Sbjct: 443 FSVSGRLLFGGYE 405

 Score = 68.9 bits (167), Expect(2) = 6e-35,   Method: Compositional matrix adjust.
 Identities = 31/50 (62%), Positives = 39/50 (78%)
 Frame = -3

Query: 290 DDFNCSVWDALKGGRSGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLRIW 339
           +D+  +VWDALKG RS +L GHDNRVSCL ++ DG ++ TGSWD  LRIW
Sbjct: 406 NDYTVNVWDALKGMRSTILYGHDNRVSCLRISPDGTSLCTGSWDYTLRIW 257

 Score = 30.8 bits (68), Expect(2) = 5e-04,   Method: Compositional matrix adjust.
 Identities = 15/49 (30%), Positives = 24/49 (48%)
 Frame = -3

Query: 205 DASSKLWDIRDGMCRQSFTGHISDINAVSFFPSGYAFATGSDDATCRLF 253
           D +  +WD   GM      GH + ++ +   P G +  TGS D T R++
Sbjct: 403 DYTVNVWDALKGMRSTILYGHDNRVSCLRISPDGTSLCTGSWDYTLRIW 257

 Score = 30.0 bits (66), Expect(2) = 5e-04,   Method: Compositional matrix adjust.
 Identities = 14/47 (29%), Positives = 21/47 (44%), Gaps = 1/47 (2%)
 Frame = -2

Query: 139 LPGHTGYLSCCRFLDDGQ-IITSSGDTTCALWDIETGQQTTTFTGHS 184
             GH   ++C RF   G    T S D TC L+D+   ++   +   S
Sbjct: 611 FEGHEADINCVRFYPSGDAFATGSDDATCRLFDLRADREVNCYRKES 471

 Score = 35.8 bits (81), Expect = 0.025,   Method: Compositional matrix adjust.
 Identities = 16/51 (31%), Positives = 27/51 (52%)
 Frame = -3

Query: 161 SGDTTCALWDIETGQQTTTFTGHSGDVMSLSLSPDLKTFVSGACDASSKLW 211
           + D T  +WD   G ++T   GH   V  L +SPD  +  +G+ D + ++W
Sbjct: 409 TNDYTVNVWDALKGMRSTILYGHDNRVSCLRISPDGTSLCTGSWDYTLRIW 257
>17598
          Length = 875

 Score = 95.5 bits (236), Expect = 3e-20,   Method: Compositional matrix adjust.
 Identities = 67/256 (26%), Positives = 115/256 (44%), Gaps = 14/256 (5%)
 Frame = +1

Query: 48  RRTLRGHLAKIYAMHWGYDSRLLVSASQDGKLIIWDSYTTNKMHAIPLRSSWVMTCAYAP 107
           RRTL+GH   +  +    DSR ++S+S D  L +WD    N        +   +  A++P
Sbjct: 100 RRTLQGHSHFVSDVSLSADSRYVLSSSWDATLRLWDIKKGNTTRRFISHTRDALAVAFSP 279

Query: 108 SGNYVACGGLDNICSIYNLKTREGNVRVSRELPGHTGYLSCCRFLDDGQ---IITSSGDT 164
               +A GG D    I+N     G  + + +   H  +++C +F  D +   ++++S D 
Sbjct: 280 DNRQIASGGRDKALKIWNT---VGECKFTVDANSHQDWVTCVKFHQDAKSPLVVSASMDK 450

Query: 165 TCALWDIETGQQTTTFTGHSGDVMSLSLSPDLKTFVSGACDASSKLWDIRDGMCRQSFTG 224
           T  +WD +T     TF GH   + ++ L+       SG+ D     W+I++G    +F G
Sbjct: 451 TIKVWDNQTMTLKHTFVGHKTQINAIDLALKTYYLASGSKDGIVMTWNIQNG----TFLG 618

Query: 225 HIS---DINAVSFFPSGYAFATGSDDA--------TCRLFDLRADQELLLYSHDNIICGI 273
            I    ++NAV F P+ Y    G+ +           ++ D+RA      +         
Sbjct: 619 KIDCDCEVNAVKFSPNKYWLFVGTSEGIQIWDLPNQKKIKDIRASPIDAQHKSQKKSIAC 798

Query: 274 TSVAFSKSGRLLLAGY 289
           TS+A+  SG  L AG+
Sbjct: 799 TSLAWDASGHTLFAGF 846

 Score = 66.6 bits (161), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 52/198 (26%), Positives = 87/198 (43%), Gaps = 14/198 (7%)
 Frame = +1

Query: 157 IITSSGDTTCALWDI---------ET-GQQTTTFTGHSGDVMSLSLSPDLKTFVSGACDA 206
           +I    D    +WD+         ET G    T  GHS  V  +SLS D +  +S + DA
Sbjct: 10  LIXGGRDKLLIVWDLVPRKDGDEDETWGGPRRTLQGHSHFVSDVSLSADSRYVLSSSWDA 189

Query: 207 SSKLWDIRDGMCRQSFTGHISDINAVSFFPSGYAFATGSDDATCRLFDLRADQELLL--Y 264
           + +LWDI+ G   + F  H  D  AV+F P     A+G  D   ++++   + +  +   
Sbjct: 190 TLRLWDIKKGNTTRRFISHTRDALAVAFSPDNRQIASGGRDKALKIWNTVGECKFTVDAN 369

Query: 265 SHDNIICGITSVAFSKSGR--LLLAGYDDFNCSVWDALKGGRSGVLAGHDNRVSCLGVTD 322
           SH +    +T V F +  +  L+++   D    VWD           GH  +++ + +  
Sbjct: 370 SHQD---WVTCVKFHQDAKSPLVVSASMDKTIKVWDNQTMTLKHTFVGHKTQINAIDLAL 540

Query: 323 DGMAVATGSWDSFLRIWN 340
               +A+GS D  +  WN
Sbjct: 541 KTYYLASGSKDGIVMTWN 594

 Score = 65.9 bits (159), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 56/243 (23%), Positives = 95/243 (39%), Gaps = 54/243 (22%)
 Frame = +1

Query: 110 NYVACGGLDNICSIYNLKTRE--------GNVRVSRELPGHTGYLSCCRFLDDGQ-IITS 160
            ++  GG D +  +++L  R+        G  R  R L GH+ ++S      D + +++S
Sbjct: 4   EFLIXGGRDKLLIVWDLVPRKDGDEDETWGGPR--RTLQGHSHFVSDVSLSADSRYVLSS 177

Query: 161 SGDTTCALWDIETGQQTTTFTGHSGDVMSLSLSPDLKTFVSG------------------ 202
           S D T  LWDI+ G  T  F  H+ D ++++ SPD +   SG                  
Sbjct: 178 SWDATLRLWDIKKGNTTRRFISHTRDALAVAFSPDNRQIASGGRDKALKIWNTVGECKFT 357

Query: 203 ---------------------------ACDASSKLWDIRDGMCRQSFTGHISDINAVSFF 235
                                      + D + K+WD +    + +F GH + INA+   
Sbjct: 358 VDANSHQDWVTCVKFHQDAKSPLVVSASMDKTIKVWDNQTMTLKHTFVGHKTQINAIDLA 537

Query: 236 PSGYAFATGSDDATCRLFDLRADQELLLYSHDNIICGITSVAFSKSGRLLLAGYDDFNCS 295
              Y  A+GS D     ++++    L     D   C + +V FS +   L  G  +    
Sbjct: 538 LKTYYLASGSKDGIVMTWNIQNGTFLGKIDCD---CEVNAVKFSPNKYWLFVGTSE-GIQ 705

Query: 296 VWD 298
           +WD
Sbjct: 706 IWD 714
>12806
          Length = 961

 Score = 87.4 bits (215), Expect = 8e-18,   Method: Compositional matrix adjust.
 Identities = 58/193 (30%), Positives = 93/193 (48%), Gaps = 6/193 (3%)
 Frame = +3

Query: 48  RRTLRGHLAKIYAMHWGYDSRLLVSASQDGKLIIWDSYTTNKMHAIPLRSSWVMTCAYAP 107
           R+TL GH   I  +    DSR  +S+S D  L +WD    +        +  V+T A++P
Sbjct: 144 RKTLTGHSHFISDLALSADSRFALSSSWDATLRLWDIKKGSTTSRFINHTRDVLTVAFSP 323

Query: 108 SGNYVACGGLDNICSIYNLKTREGNVRVSRELPGHTGYLSCCRFLDDGQ---IITSSGDT 164
               +A GG D    I+N+    G  + + +   HT +++C RF  D +   ++++S D 
Sbjct: 324 DNRQIASGGRDKNLKIWNIM---GECKYTVDANAHTDWVTCVRFHQDTKNPIVVSASNDK 494

Query: 165 TCALWDIETGQQTTTFTGHSGDVMSLSLSPDLKTFVSGACDASSKLWDIRDGMCRQSFTG 224
           T  +WD  T     TF GH   + +L +S +    VSG+ D  +  W++ +G    SF G
Sbjct: 495 TIKVWDNHTMTLKNTFVGHKAQITALDMSTNY--LVSGSKDGIAMTWNVAEG----SFVG 656

Query: 225 HI---SDINAVSF 234
            I     INA+ F
Sbjct: 657 KIDCDDQINAIKF 695

 Score = 63.5 bits (153), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 42/169 (24%), Positives = 80/169 (47%), Gaps = 2/169 (1%)
 Frame = +3

Query: 174 GQQTTTFTGHSGDVMSLSLSPDLKTFVSGACDASSKLWDIRDGMCRQSFTGHISDINAVS 233
           G    T TGHS  +  L+LS D +  +S + DA+ +LWDI+ G     F  H  D+  V+
Sbjct: 135 GVPRKTLTGHSHFISDLALSADSRFALSSSWDATLRLWDIKKGSTTSRFINHTRDVLTVA 314

Query: 234 FFPSGYAFATGSDDATCRLFDLRADQELLLYSHDNIICGITSVAFSKSGR--LLLAGYDD 291
           F P     A+G  D   +++++  + +  + ++ +    +T V F +  +  ++++  +D
Sbjct: 315 FSPDNRQIASGGRDKNLKIWNIMGECKYTVDANAHTDW-VTCVRFHQDTKNPIVVSASND 491

Query: 292 FNCSVWDALKGGRSGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLRIWN 340
               VWD           GH  +++ L ++ + +   +GS D     WN
Sbjct: 492 KTIKVWDNHTMTLKNTFVGHKAQITALDMSTNYL--VSGSKDGIAMTWN 632
>34511
          Length = 1037

 Score = 75.9 bits (185), Expect(2) = 9e-16,   Method: Compositional matrix adjust.
 Identities = 33/40 (82%), Positives = 38/40 (95%)
 Frame = +3

Query: 301 KGGRSGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLRIWN 340
           K  RSG+LAGHDNRVSCLGVT++GM+VATGSWDSFLR+WN
Sbjct: 39  KAERSGILAGHDNRVSCLGVTENGMSVATGSWDSFLRVWN 158

 Score = 24.6 bits (52), Expect(2) = 9e-16,   Method: Compositional matrix adjust.
 Identities = 8/13 (61%), Positives = 11/13 (84%)
 Frame = +2

Query: 289 YDDFNCSVWDALK 301
           YDDFNC+VW  ++
Sbjct: 2   YDDFNCNVWYTME 40
>30256
          Length = 961

 Score = 79.7 bits (195), Expect = 2e-15,   Method: Compositional matrix adjust.
 Identities = 63/207 (30%), Positives = 103/207 (49%)
 Frame = +3

Query: 134 RVSRELPGHTGYLSCCRFLDDGQIITSSGDTTCALWDIETGQQTTTFTGHSGDVMSLSLS 193
           R  + L GHTG +   +   +  +I+ S D +  +W+ +TG  T T  GHS  V  LSLS
Sbjct: 15  RCIKNLIGHTGGVWSSQMTGN-TVISGSTDRSLKVWNADTGVCTHTLYGHSSTVRCLSLS 191

Query: 194 PDLKTFVSGACDASSKLWDIRDGMCRQSFTGHISDINAVSFFPSGYAFATGSDDATCRLF 253
              K  VSG+ DA+ ++WDI  G C     GH++ +  V +   G    +G+ D T R++
Sbjct: 192 G--KKVVSGSRDATLRVWDIESGHCLNVLLGHMAAVRCVQY--DGKRVVSGAXDYTVRVW 359

Query: 254 DLRADQELLLYSHDNIICGITSVAFSKSGRLLLAGYDDFNCSVWDALKGGRSGVLAGHDN 313
           D   D    L++       + S+ F   G  +++G  D +  VWD   G     L GH +
Sbjct: 360 D--PDTASCLHTLQGHTNRVYSLQF--DGVYVVSGSLDTSIRVWDVRCGKLVHTLMGHQS 527

Query: 314 RVSCLGVTDDGMAVATGSWDSFLRIWN 340
             S L + D+   + +G+ DS +++W+
Sbjct: 528 LTSGLELKDN--LLVSGNADSTVKVWD 602

 Score = 72.4 bits (176), Expect = 2e-13,   Method: Compositional matrix adjust.
 Identities = 65/262 (24%), Positives = 111/262 (42%), Gaps = 18/262 (6%)
 Frame = +3

Query: 50  TLRGHLAKIYAMHWGYDSRLLVSASQDGKLIIWDSYTTNKMHAIPLRSSWVMTCAYAPSG 109
           TL GH + +  +      + +VS S+D  L +WD  + + ++ +    + V    Y   G
Sbjct: 147 TLYGHSSTVRCL--SLSGKKVVSGSRDATLRVWDIESGHCLNVLLGHMAAVRCVQY--DG 314

Query: 110 NYVACGGLDNICSIYNLKTREGNVRVSRELPGHTGYLSCCRFLDDGQIITSSGDTTCALW 169
             V  G  D    +++  T          L GHT  +   +F D   +++ S DT+  +W
Sbjct: 315 KRVVSGAXDYTVRVWDPDTAS----CLHTLQGHTNRVYSLQF-DGVYVVSGSLDTSIRVW 479

Query: 170 DIETGQQTTTFTGHSGDVMSLSLSPDLKTFVSGACDASSKLWDIRDGMCRQSFTGHISDI 229
           D+  G+   T  GH      L L  +L   VSG  D++ K+WD+  G C Q+  G     
Sbjct: 480 DVRCGKLVHTLMGHQSLTSGLELKDNL--LVSGNADSTVKVWDVHTGKCLQTLLGPNKHR 653

Query: 230 NAVSFFPSGYAF-ATGSDDATCRLFDLRADQEL-----------------LLYSHDNIIC 271
           +AV+       F  T SDD T +L+DL     +                 L  ++  ++C
Sbjct: 654 SAVTCLQFNKKFVVTCSDDGTVKLWDLNTGDFIRNLITLPSGGSGGVVWRLRCNNTKMVC 833

Query: 272 GITSVAFSKSGRLLLAGYDDFN 293
            + S   ++  +LL+  +D  N
Sbjct: 834 AVGSRNGTEETKLLVLDFDQVN 899
>13335
          Length = 863

 Score = 78.6 bits (192), Expect = 3e-15,   Method: Compositional matrix adjust.
 Identities = 60/216 (27%), Positives = 96/216 (44%), Gaps = 24/216 (11%)
 Frame = +1

Query: 149 CRF-LDDGQIITSSGDTTCALWDIETGQQTTTFTGHSGDVMSLSLSPDLKTFVSGACDAS 207
           C+F      +++ S D T  +W++ T +   ++ GH   VM+L+ SP+    VSG+ +  
Sbjct: 79  CKFSPSSSHLVSGSDDDTICMWEVATQKLVRSYVGHEDSVMALAYSPNGHYLVSGSPNGD 258

Query: 208 SKLWDIRDGMCRQ---SFTGHISDINAVSFFPS------------GYAFATGSDDATCRL 252
             +WD   G CR        H   +    F P+                ATG  D   +L
Sbjct: 259 LYVWDASFGHCRHLTLRVDAHDLGVTCCEFSPTFGTACAENSSTCNLLLATGGKDNLIKL 438

Query: 253 FDLRAD---QELLLYSHDNIICG----ITSVAFSKSGRLLLAGYDDFNCSVWDALKG-GR 304
           +   A     E+ L   D I+ G    + + AFS S  LL +G  D +  +WD++KG   
Sbjct: 439 WTFSAQVGSPEVTLQCRD-ILSGHSDLVMACAFSPSSALLASGSFDKSVRLWDSVKGVAL 615

Query: 305 SGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLRIWN 340
             + A H   V+C   + DG  +A+GS D  ++IW 
Sbjct: 616 FSIEACHSRFVTCCAFSIDGTLLASGSMDRIIKIWK 723

 Score = 54.3 bits (129), Expect = 7e-08,   Method: Compositional matrix adjust.
 Identities = 52/209 (24%), Positives = 84/209 (40%), Gaps = 23/209 (11%)
 Frame = +1

Query: 70  LVSASQDGKLIIWDSYTTNKMHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTR 129
           LVS S D  + +W+  T   + +       VM  AY+P+G+Y+  G  +    +Y     
Sbjct: 106 LVSGSDDDTICMWEVATQKLVRSYVGHEDSVMALAYSPNGHYLVSGSPNG--DLYVWDAS 279

Query: 130 EGNVR-VSRELPGHTGYLSCCRFLDDGQIITSSGDTTC-------------ALWDI--ET 173
            G+ R ++  +  H   ++CC F        +   +TC              LW    + 
Sbjct: 280 FGHCRHLTLRVDAHDLGVTCCEFSPTFGTACAENSSTCNLLLATGGKDNLIKLWTFSAQV 459

Query: 174 GQQTTT------FTGHSGDVMSLSLSPDLKTFVSGACDASSKLWDIRDGMCRQSFTG-HI 226
           G    T       +GHS  VM+ + SP      SG+ D S +LWD   G+   S    H 
Sbjct: 460 GSPEVTLQCRDILSGHSDLVMACAFSPSSALLASGSFDKSVRLWDSVKGVALFSIEACHS 639

Query: 227 SDINAVSFFPSGYAFATGSDDATCRLFDL 255
             +   +F   G   A+GS D   +++ L
Sbjct: 640 RFVTCCAFSIDGTLLASGSMDRIIKIWKL 726

 Score = 51.6 bits (122), Expect = 4e-07,   Method: Compositional matrix adjust.
 Identities = 51/206 (24%), Positives = 89/206 (43%), Gaps = 25/206 (12%)
 Frame = +1

Query: 35  SNMDSVGRIQMRTRRTLR---GHLAKIYAMHWGYDSRLLVSASQDGKLIIWDSYTTNKMH 91
           S+ D++   ++ T++ +R   GH   + A+ +  +   LVS S +G L +WD+   +  H
Sbjct: 118 SDDDTICMWEVATQKLVRSYVGHEDSVMALAYSPNGHYLVSGSPNGDLYVWDASFGHCRH 297

Query: 92  AIPLRSSW----VMTCAYAPS------------GNYVACGGLDNICSIYNLKTREGNVRV 135
            + LR       V  C ++P+               +A GG DN+  ++    + G+  V
Sbjct: 298 -LTLRVDAHDLGVTCCEFSPTFGTACAENSSTCNLLLATGGKDNLIKLWTFSAQVGSPEV 474

Query: 136 SRE----LPGHTGYLSCCRFLDDGQIITS-SGDTTCALWDIETGQQTTTFTG-HSGDVMS 189
           + +    L GH+  +  C F     ++ S S D +  LWD   G    +    HS  V  
Sbjct: 475 TLQCRDILSGHSDLVMACAFSPSSALLASGSFDKSVRLWDSVKGVALFSIEACHSRFVTC 654

Query: 190 LSLSPDLKTFVSGACDASSKLWDIRD 215
            + S D     SG+ D   K+W + D
Sbjct: 655 CAFSIDGTLLASGSMDRIIKIWKLTD 732
>27465
          Length = 658

 Score = 78.6 bits (192), Expect = 4e-15,   Method: Compositional matrix adjust.
 Identities = 40/104 (38%), Positives = 57/104 (54%), Gaps = 1/104 (0%)
 Frame = -1

Query: 157 IITSSGDTTCALWDIETGQQTTTFTGHSGDVMSLSLS-PDLKTFVSGACDASSKLWDIRD 215
            IT S D TC +WD  + ++  T  GH   V +++ + P     ++G+ D + KLW   D
Sbjct: 316 FITGSYDRTCKIWDTASAEELHTLEGHRNVVYAIAFNNPFGDKVITGSFDKTCKLWSTAD 137

Query: 216 GMCRQSFTGHISDINAVSFFPSGYAFATGSDDATCRLFDLRADQ 259
           G C  +  GH ++I  VSF PS    ATGS D TCRL+D+   Q
Sbjct: 136 GKCYHTLRGHTAEIVCVSFNPSSTLIATGSMDTTCRLWDVEKAQ 5

 Score = 63.9 bits (154), Expect = 9e-11,   Method: Compositional matrix adjust.
 Identities = 39/119 (32%), Positives = 59/119 (49%), Gaps = 2/119 (1%)
 Frame = -1

Query: 224 GHISDINAVSFFPSGYAFATGSDDATCRLFDLRADQEL-LLYSHDNIICGITSVAFSKS- 281
            HI  +  V+F  SG +F TGS D TC+++D  + +EL  L  H N++  I   AF+   
Sbjct: 367 AHILPLTNVAFNKSGSSFITGSYDRTCKIWDTASAEELHTLEGHRNVVYAI---AFNNPF 197

Query: 282 GRLLLAGYDDFNCSVWDALKGGRSGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLRIWN 340
           G  ++ G  D  C +W    G     L GH   + C+        +ATGS D+  R+W+
Sbjct: 196 GDKVITGSFDKTCKLWSTADGKCYHTLRGHTAEIVCVSFNPSSTLIATGSMDTTCRLWD 20

 Score = 58.5 bits (140), Expect = 4e-09,   Method: Compositional matrix adjust.
 Identities = 37/130 (28%), Positives = 61/130 (46%), Gaps = 2/130 (1%)
 Frame = -1

Query: 49  RTLRGHLAKIYAMHWGYDSRLLVSASQDGKLIIWDSYTTNKMHAIPLRSSWVMTCAYA-P 107
           + LR H+  +  + +       ++ S D    IWD+ +  ++H +    + V   A+  P
Sbjct: 379 KVLRAHILPLTNVAFNKSGSSFITGSYDRTCKIWDTASAEELHTLEGHRNVVYAIAFNNP 200

Query: 108 SGNYVACGGLDNICSIYNLKTREGNVRVSRELPGHTGYLSCCRFLDDGQII-TSSGDTTC 166
            G+ V  G  D  C +++  T +G  +    L GHT  + C  F     +I T S DTTC
Sbjct: 199 FGDKVITGSFDKTCKLWS--TADG--KCYHTLRGHTAEIVCVSFNPSSTLIATGSMDTTC 32

Query: 167 ALWDIETGQQ 176
            LWD+E  Q+
Sbjct: 31  RLWDVEKAQR 2

 Score = 55.5 bits (132), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 34/131 (25%), Positives = 58/131 (44%), Gaps = 2/131 (1%)
 Frame = -1

Query: 89  KMHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELPGHTGYLSC 148
           + H +PL +      A+  SG+    G  D  C I++  + E        L GH   +  
Sbjct: 370 RAHILPLTN-----VAFNKSGSSFITGSYDRTCKIWDTASAEE----LHTLEGHRNVVYA 218

Query: 149 CRFLDD--GQIITSSGDTTCALWDIETGQQTTTFTGHSGDVMSLSLSPDLKTFVSGACDA 206
             F +    ++IT S D TC LW    G+   T  GH+ +++ +S +P      +G+ D 
Sbjct: 217 IAFNNPFGDKVITGSFDKTCKLWSTADGKCYHTLRGHTAEIVCVSFNPSSTLIATGSMDT 38

Query: 207 SSKLWDIRDGM 217
           + +LWD+    
Sbjct: 37  TCRLWDVEKAQ 5

 Score = 48.9 bits (115), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 37/127 (29%), Positives = 61/127 (48%), Gaps = 4/127 (3%)
 Frame = -1

Query: 182 GHSGDVMSLSLSPDLKTFVSGACDASSKLWDIRDGMCRQSFTGHISDINAVSF-FPSGYA 240
            H   + +++ +    +F++G+ D + K+WD        +  GH + + A++F  P G  
Sbjct: 367 AHILPLTNVAFNKSGSSFITGSYDRTCKIWDTASAEELHTLEGHRNVVYAIAFNNPFGDK 188

Query: 241 FATGSDDATCRLFDLRADQELL--LYSHD-NIICGITSVAFSKSGRLLLAGYDDFNCSVW 297
             TGS D TC+L+   AD +    L  H   I+C    V+F+ S  L+  G  D  C +W
Sbjct: 187 VITGSFDKTCKLWST-ADGKCYHTLRGHTAEIVC----VSFNPSSTLIATGSMDTTCRLW 23

Query: 298 DALKGGR 304
           D  K  R
Sbjct: 22  DVEKAQR 2
>02147
          Length = 1547

 Score = 75.9 bits (185), Expect = 2e-14,   Method: Compositional matrix adjust.
 Identities = 58/220 (26%), Positives = 91/220 (41%), Gaps = 38/220 (17%)
 Frame = +2

Query: 159 TSSGDTTCALWDIETGQQTTTFTGHSGDVMSLSLSPDLKTFVSGACDASSKLWDIRDGMC 218
           T + D +  +WD E G++  TF+ H   V S+  S D    ++G+ +   K++D+ +   
Sbjct: 224 TGAADFSAKIWDAEKGEELQTFS-HKHIVKSVDFSHDGTALLTGSNEKLLKVFDLVNTDA 400

Query: 219 R-QSFTGHISDINAVSFFPSGYAFATGSDDATCRLFDLRADQEL---------------- 261
             +SF GH S+I    F   G    + SDD T RL+ L   QE+                
Sbjct: 401 EPKSFAGHTSNIKGALFLSDGKRIISASDDKTVRLWSLETCQEVQQLTFDTPPTSLTLSP 580

Query: 262 ----LLYSHDNIIC-----------------GITSVAFSKSGRLLLAGYDDFNCSVWDAL 300
               ++ +H   I                   I+S +  +S R  +AG +DF    +D  
Sbjct: 581 DKNTIIVTHSQNIAFYQADTLREMKKFEAEAPISSASLHQSERFFVAGGEDFKMYKFDYE 760

Query: 301 KGGRSGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLRIWN 340
            G       GH   V C+  + DG   A+GS D  LR+W 
Sbjct: 761 TGKEIESFKGHFGPVHCVRFSPDGELYASGSEDGTLRLWQ 880

 Score = 69.7 bits (169), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 57/244 (23%), Positives = 94/244 (38%), Gaps = 41/244 (16%)
 Frame = +2

Query: 50  TLRGHLAKIYAMHWGYDSRLLVSASQDGKLIIWDSYTTNKMHAIPLRSSWVMTCAYAPSG 109
           T  GH   ++      ++    + + D    IWD+    ++     +   V +  ++  G
Sbjct: 158 TFEGHKGAVWGATLNREATRAATGAADFSAKIWDAEKGEELQTFSHKHI-VKSVDFSHDG 334

Query: 110 NYVACGGLDNICSIYNLKTREGNVRVSRELPGHTGYLSCCRFLDDGQ-IITSSGDTTCAL 168
             +  G  + +  +++L   +      +   GHT  +    FL DG+ II++S D T  L
Sbjct: 335 TALLTGSNEKLLKVFDLVNTDAE---PKSFAGHTSNIKGALFLSDGKRIISASDDKTVRL 505

Query: 169 WDIETGQQTTTFTGHSGDVMSLSLSPDLKT------------------------------ 198
           W +ET Q+    T  +    SL+LSPD  T                              
Sbjct: 506 WSLETCQEVQQLTFDTPPT-SLTLSPDKNTIIVTHSQNIAFYQADTLREMKKFEAEAPIS 682

Query: 199 ----------FVSGACDASSKLWDIRDGMCRQSFTGHISDINAVSFFPSGYAFATGSDDA 248
                     FV+G  D     +D   G   +SF GH   ++ V F P G  +A+GS+D 
Sbjct: 683 SASLHQSERFFVAGGEDFKMYKFDYETGKEIESFKGHFGPVHCVRFSPDGELYASGSEDG 862

Query: 249 TCRL 252
           T RL
Sbjct: 863 TLRL 874

 Score = 52.4 bits (124), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 39/164 (23%), Positives = 68/164 (41%), Gaps = 1/164 (0%)
 Frame = +2

Query: 49  RTLRGHLAKIYAMHWGYDSRLLVSASQDGKLIIWDSYTTNKMHAIPLRSSWVMTCAYAPS 108
           ++  GH + I    +  D + ++SAS D  + +W   T  ++  +   +    +   +P 
Sbjct: 407 KSFAGHTSNIKGALFLSDGKRIISASDDKTVRLWSLETCQEVQQLTFDTP-PTSLTLSPD 583

Query: 109 GNYVACGGLDNICSIYNLKTREGNVRVSRELPGHTGYL-SCCRFLDDGQIITSSGDTTCA 167
            N +      NI   Y   T     +   E P  +  L    RF      +    D    
Sbjct: 584 KNTIIVTHSQNIA-FYQADTLREMKKFEAEAPISSASLHQSERFF-----VAGGEDFKMY 745

Query: 168 LWDIETGQQTTTFTGHSGDVMSLSLSPDLKTFVSGACDASSKLW 211
            +D ETG++  +F GH G V  +  SPD + + SG+ D + +LW
Sbjct: 746 KFDYETGKEIESFKGHFGPVHCVRFSPDGELYASGSEDGTLRLW 877

 Score = 46.2 bits (108), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 32/121 (26%), Positives = 55/121 (45%), Gaps = 1/121 (0%)
 Frame = +2

Query: 221 SFTGHISDINAVSFFPSGYAFATGSDDATCRLFDLRADQELLLYSHDNIICGITSVAFSK 280
           +F GH   +   +        ATG+ D + +++D    +EL  +SH +I+    SV FS 
Sbjct: 158 TFEGHKGAVWGATLNREATRAATGAADFSAKIWDAEKGEELQTFSHKHIV---KSVDFSH 328

Query: 281 SGRLLLAGYDDFNCSVWDALK-GGRSGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLRIW 339
            G  LL G ++    V+D +         AGH + +       DG  + + S D  +R+W
Sbjct: 329 DGTALLTGSNEKLLKVFDLVNTDAEPKSFAGHTSNIKGALFLSDGKRIISASDDKTVRLW 508

Query: 340 N 340
           +
Sbjct: 509 S 511
>00561
          Length = 1003

 Score = 70.9 bits (172), Expect = 8e-13,   Method: Compositional matrix adjust.
 Identities = 61/246 (24%), Positives = 107/246 (43%), Gaps = 13/246 (5%)
 Frame = -3

Query: 66  DSRLLVSASQDGKLIIWD---------SYTTNKMHAIPLRSSWVMTCAYAPSGNYVACGG 116
           D   ++SAS+D  LI+W           Y   +++     S ++     +  GNY   G 
Sbjct: 977 DPDTIISASRDKTLIVWKLTRDEDTNYGYPQKRLYG---HSHFISDVVLSSDGNYALSGS 807

Query: 117 LDNICSIYNLKTREGNVRVSRELPGHTG-YLSCCRFLDDGQIITSSGDTTCALWD-IETG 174
            D    +++L       + +R   GHT   LS     D+ QI++ S D T  LW+ +   
Sbjct: 806 WDQTLRLWDLAAG----KTTRRFEGHTKDVLSVAFSADNRQIVSGSRDKTIKLWNTLAEC 639

Query: 175 QQTTTFTGHSGDVMSLSLSPDLKTFVSGAC--DASSKLWDIRDGMCRQSFTGHISDINAV 232
           + T    GH+  V  +  SP+    +  +C  D + K+W++ +   + +  GH   +N V
Sbjct: 638 KFTIQEDGHTDWVSCVRFSPNHSNPIIVSCGWDRTVKVWNLANCKLKNNHHGHNGYLNTV 459

Query: 233 SFFPSGYAFATGSDDATCRLFDLRADQELLLYSHDNIICGITSVAFSKSGRLLLAGYDDF 292
           +  P G    +G  D+   L+DL   + L    H++I   I ++ FS +   L   Y   
Sbjct: 458 TVSPDGSLCTSGGKDSKALLWDLNDGKNLYTLEHNDI---INALCFSPNRYWLCVAYGP- 291

Query: 293 NCSVWD 298
           +  +WD
Sbjct: 290 SIKIWD 273

 Score = 64.3 bits (155), Expect = 6e-11,   Method: Compositional matrix adjust.
 Identities = 51/196 (26%), Positives = 87/196 (44%), Gaps = 8/196 (4%)
 Frame = -3

Query: 153 DDGQIITSSGDTTCALW------DIETGQQTTTFTGHSGDVMSLSLSPDLKTFVSGACDA 206
           D   II++S D T  +W      D   G       GHS  +  + LS D    +SG+ D 
Sbjct: 977 DPDTIISASRDKTLIVWKLTRDEDTNYGYPQKRLYGHSHFISDVVLSSDGNYALSGSWDQ 798

Query: 207 SSKLWDIRDGMCRQSFTGHISDINAVSFFPSGYAFATGSDDATCRLFDLRADQELLLYSH 266
           + +LWD+  G   + F GH  D+ +V+F        +GS D T +L++  A+ +  +   
Sbjct: 797 TLRLWDLAAGKTTRRFEGHTKDVLSVAFSADNRQIVSGSRDKTIKLWNTLAECKFTI-QE 621

Query: 267 DNIICGITSVAFSK--SGRLLLAGYDDFNCSVWDALKGGRSGVLAGHDNRVSCLGVTDDG 324
           D     ++ V FS   S  ++++   D    VW+           GH+  ++ + V+ DG
Sbjct: 620 DGHTDWVSCVRFSPNHSNPIIVSCGWDRTVKVWNLANCKLKNNHHGHNGYLNTVTVSPDG 441

Query: 325 MAVATGSWDSFLRIWN 340
               +G  DS   +W+
Sbjct: 440 SLCTSGGKDSKALLWD 393

 Score = 63.9 bits (154), Expect = 8e-11,   Method: Compositional matrix adjust.
 Identities = 59/213 (27%), Positives = 99/213 (46%), Gaps = 9/213 (4%)
 Frame = -3

Query: 137 RELPGHTGYLSCCRFLDDGQI-ITSSGDTTCALWDIETGQQTTTFTGHSGDVMSLSLSPD 195
           + L GH+ ++S      DG   ++ S D T  LWD+  G+ T  F GH+ DV+S++ S D
Sbjct: 884 KRLYGHSHFISDVVLSSDGNYALSGSWDQTLRLWDLAAGKTTRRFEGHTKDVLSVAFSAD 705

Query: 196 LKTFVSGACDASSKLWDIRDGMCRQSFT----GHISDINAVSFFP--SGYAFATGSDDAT 249
            +  VSG+ D + KLW+    +    FT    GH   ++ V F P  S     +   D T
Sbjct: 704 NRQIVSGSRDKTIKLWNT---LAECKFTIQEDGHTDWVSCVRFSPNHSNPIIVSCGWDRT 534

Query: 250 CRLFDLRADQELLLYSHDNIICGITSVAFSKSGRLLLAGYDDFNCSVWDALKGGRSGVLA 309
            ++++L   +  L  +H      + +V  S  G L  +G  D    +WD L  G++    
Sbjct: 533 VKVWNLANCK--LKNNHHGHNGYLNTVTVSPDGSLCTSGGKDSKALLWD-LNDGKNLYTL 363

Query: 310 GHDNRVS--CLGVTDDGMAVATGSWDSFLRIWN 340
            H++ ++  C       + VA G     ++IW+
Sbjct: 362 EHNDIINALCFSPNRYWLCVAYG---PSIKIWD 273

 Score = 61.6 bits (148), Expect = 5e-10,   Method: Compositional matrix adjust.
 Identities = 46/172 (26%), Positives = 80/172 (46%), Gaps = 4/172 (2%)
 Frame = -3

Query: 46  RTRRTLRGHLAKIYAMHWGYDSRLLVSASQDGKLIIWDSYTTNKMHAIPL-RSSWVMTCA 104
           +T R   GH   + ++ +  D+R +VS S+D  + +W++    K        + WV    
Sbjct: 767 KTTRRFEGHTKDVLSVAFSADNRQIVSGSRDKTIKLWNTLAECKFTIQEDGHTDWVSCVR 588

Query: 105 YAP--SGNYVACGGLDNICSIYNLKTREGNVRVSRELPGHTGYLSCCRFLDDGQIITSSG 162
           ++P  S   +   G D    ++NL     N ++     GH GYL+      DG + TS G
Sbjct: 587 FSPNHSNPIIVSCGWDRTVKVWNL----ANCKLKNNHHGHNGYLNTVTVSPDGSLCTSGG 420

Query: 163 -DTTCALWDIETGQQTTTFTGHSGDVMSLSLSPDLKTFVSGACDASSKLWDI 213
            D+   LWD+  G+   T   H+  + +L  SP+ + ++  A   S K+WD+
Sbjct: 419 KDSKALLWDLNDGKNLYTLE-HNDIINALCFSPN-RYWLCVAYGPSIKIWDL 270
>19949
          Length = 903

 Score = 68.2 bits (165), Expect = 5e-12,   Method: Compositional matrix adjust.
 Identities = 42/149 (28%), Positives = 69/149 (46%), Gaps = 1/149 (0%)
 Frame = +2

Query: 100 VMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELPGHTGYLSCCRFLDDGQ-II 158
           V +  + P G Y A G +D    +++++ R+G +   +   GHTG + C RF  DG+ I 
Sbjct: 2   VKSLDFHPYGAYTASGSMDCNVKLWDIR-RKGCIYTYK---GHTGCVCCLRFSPDGRWIA 169

Query: 159 TSSGDTTCALWDIETGQQTTTFTGHSGDVMSLSLSPDLKTFVSGACDASSKLWDIRDGMC 218
           ++S D    LWD+  G+  T    H   V ++   P      SG+ D + K WD+     
Sbjct: 170 SASEDGLVKLWDLTAGKLLTDLKLHRDAVNTIEFHPHEFLLASGSADRTVKFWDLETFQL 349

Query: 219 RQSFTGHISDINAVSFFPSGYAFATGSDD 247
             +     + I ++ F P G    +GS D
Sbjct: 350 ISTTEPEANSIRSILFHPDGVCLYSGSKD 436

 Score = 67.0 bits (162), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 46/146 (31%), Positives = 65/146 (44%), Gaps = 3/146 (2%)
 Frame = +2

Query: 159 TSSGDTTC--ALWDIETGQQTTTFTGHSGDVMSLSLSPDLKTFVSGACDASSKLWDIRDG 216
           T+SG   C   LWDI       T+ GH+G V  L  SPD +   S + D   KLWD+  G
Sbjct: 38  TASGSMDCNVKLWDIRRKGCIYTYKGHTGCVCCLRFSPDGRWIASASEDGLVKLWDLTAG 217

Query: 217 MCRQSFTGHISDINAVSFFPSGYAFATGSDDATCRLFDLRADQELLLYSHDNIICGITSV 276
                   H   +N + F P  +  A+GS D T + +DL   Q  L+ + +     I S+
Sbjct: 218 KLLTDLKLHRDAVNTIEFHPHEFLLASGSADRTVKFWDLETFQ--LISTTEPEANSIRSI 391

Query: 277 AFSKSGRLLLAGYDD-FNCSVWDALK 301
            F   G  L +G  D      W+ L+
Sbjct: 392 LFHPDGVCLYSGSKDTLKVYHWEPLE 469

 Score = 55.8 bits (133), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 43/155 (27%), Positives = 69/155 (44%), Gaps = 1/155 (0%)
 Frame = +2

Query: 187 VMSLSLSPDLKTFVSGACDASSKLWDIRDGMCRQSFTGHISDINAVSFFPSGYAFATGSD 246
           V SL   P      SG+ D + KLWDIR   C  ++ GH   +  + F P G   A+ S+
Sbjct: 2   VKSLDFHPYGAYTASGSMDCNVKLWDIRRKGCIYTYKGHTGCVCCLRFSPDGRWIASASE 181

Query: 247 DATCRLFDLRADQELL-LYSHDNIICGITSVAFSKSGRLLLAGYDDFNCSVWDALKGGRS 305
           D   +L+DL A + L  L  H +    + ++ F     LL +G  D     WD       
Sbjct: 182 DGLVKLWDLTAGKLLTDLKLHRD---AVNTIEFHPHEFLLASGSADRTVKFWDLETFQLI 352

Query: 306 GVLAGHDNRVSCLGVTDDGMAVATGSWDSFLRIWN 340
                  N +  +    DG+ + +GS D+ L++++
Sbjct: 353 STTEPEANSIRSILFHPDGVCLYSGSKDT-LKVYH 454

 Score = 38.1 bits (87), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 35/144 (24%), Positives = 59/144 (40%)
 Frame = +2

Query: 50  TLRGHLAKIYAMHWGYDSRLLVSASQDGKLIIWDSYTTNKMHAIPLRSSWVMTCAYAPSG 109
           T +GH   +  + +  D R + SAS+DG + +WD      +  + L    V T  + P  
Sbjct: 104 TYKGHTGCVCCLRFSPDGRWIASASEDGLVKLWDLTAGKLLTDLKLHRDAVNTIEFHPHE 283

Query: 110 NYVACGGLDNICSIYNLKTREGNVRVSRELPGHTGYLSCCRFLDDGQIITSSGDTTCALW 169
             +A G  D     ++L+T +    +S   P      S   F  DG  + S    T  ++
Sbjct: 284 FLLASGSADRTVKFWDLETFQ---LISTTEPEANSIRSIL-FHPDGVCLYSGSKDTLKVY 451

Query: 170 DIETGQQTTTFTGHSGDVMSLSLS 193
             E  +   T +   G V  +S+S
Sbjct: 452 HWEPLELYDTVSVPWGQVCDMSIS 523

 Score = 37.4 bits (85), Expect = 0.010,   Method: Compositional matrix adjust.
 Identities = 30/135 (22%), Positives = 56/135 (41%), Gaps = 1/135 (0%)
 Frame = +2

Query: 72  SASQDGKLIIWDSYTTNKMHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTREG 131
           S S D  + +WD      ++     +  V    ++P G ++A    D +  +++L     
Sbjct: 44  SGSMDCNVKLWDIRRKGCIYTYKGHTGCVCCLRFSPDGRWIASASEDGLVKLWDLTAG-- 217

Query: 132 NVRVSRELPGHTGYLSCCRFLDDGQIITS-SGDTTCALWDIETGQQTTTFTGHSGDVMSL 190
             ++  +L  H   ++   F     ++ S S D T   WD+ET Q  +T    +  + S+
Sbjct: 218 --KLLTDLKLHRDAVNTIEFHPHEFLLASGSADRTVKFWDLETFQLISTTEPEANSIRSI 391

Query: 191 SLSPDLKTFVSGACD 205
              PD     SG+ D
Sbjct: 392 LFHPDGVCLYSGSKD 436
>02960
          Length = 1577

 Score = 66.2 bits (160), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 50/160 (31%), Positives = 82/160 (51%), Gaps = 7/160 (4%)
 Frame = +2

Query: 139  LPGHTGYLSCCRFLDDGQIITSSGDTTCALWDIETGQQTTTFTGHSGDVMSLSLSPDLKT 198
            L GH   +S  R+LD  +++TSS D +  LWD+ T QQT+   G S  V+ ++ SP    
Sbjct: 947  LSGHAEAVSAVRWLDPHRVVTSSWDHSLRLWDLHTAQQTSLIQG-SKAVLDVAYSPLSHM 1123

Query: 199  FVSGACDASSKLWDIR--DG-MCRQSFTGHISDINAVSFFPS-GYAFATGSDDATCRLFD 254
             ++G+ D   +L D R  +G   + +FT H   +  V + P+  + F +GS D   +L+D
Sbjct: 1124 LITGSADRHVRLVDPRCSEGETVKCAFTSHTGWVTGVDWSPTREHLFLSGSYDNVLKLWD 1303

Query: 255  LRADQELLL---YSHDNIICGITSVAFSKSGRLLLAGYDD 291
             R+ +  L    +  D I+    +V +S    LL  G D+
Sbjct: 1304 TRSPKATLYDMNWHEDRIL----AVDWSIPELLLSGGVDN 1411

 Score = 43.9 bits (102), Expect = 9e-05,   Method: Compositional matrix adjust.
 Identities = 50/195 (25%), Positives = 79/195 (40%), Gaps = 9/195 (4%)
 Frame = +2

Query: 155 GQIITSSGDTTCALWDIETGQQTTTFTGHSGDVMSLSL-----SPDLKTFVSGACDASSK 209
           G  ++ S D T  LW  + G+   T  GH+  V  ++      S  + TFV+G+ D ++ 
Sbjct: 518 GXXLSGSYDNTVRLWSTK-GEAIMTIPGHTSPVKCVAWIKHDESSGVSTFVTGSHDQTAL 694

Query: 210 LW----DIRDGMCRQSFTGHISDINAVSFFPSGYAFATGSDDATCRLFDLRADQELLLYS 265
           +W    +  +  CR S  GH + ++ V+  P      TGS            D+ L L+S
Sbjct: 695 VWQWQRETNEVDCRLSCRGHAASVDCVAVSPDSQQMCTGS-----------WDKMLKLWS 841

Query: 266 HDNIICGITSVAFSKSGRLLLAGYDDFNCSVWDALKGGRSGVLAGHDNRVSCLGVTDDGM 325
            D  + G  S    +  +   +        V           L+GH   VS +    D  
Sbjct: 842 TDCNVDGDQSEDTERPSKKKKSAKSTTQTRV-------PVLTLSGHAEAVSAVRWL-DPH 997

Query: 326 AVATGSWDSFLRIWN 340
            V T SWD  LR+W+
Sbjct: 998 RVVTSSWDHSLRLWD 1042

 Score = 43.5 bits (101), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 49/213 (23%), Positives = 84/213 (39%), Gaps = 36/213 (16%)
 Frame = +2

Query: 115 GGLDNICSIYNLKTREGNVRVSRELPGHTGYLSCCRFLDDGQ------IITSSGDTTCAL 168
           G  DN   +++ K   G   ++  +PGHT  + C  ++   +       +T S D T  +
Sbjct: 533 GSYDNTVRLWSTK---GEAIMT--IPGHTSPVKCVAWIKHDESSGVSTFVTGSHDQTALV 697

Query: 169 WDI--ETGQQTTTFT--GHSGDVMSLSLSPDLKTFVSGACDASSKLW--------DIRDG 216
           W    ET +     +  GH+  V  +++SPD +   +G+ D   KLW        D  + 
Sbjct: 698 WQWQRETNEVDCRLSCRGHAASVDCVAVSPDSQQMCTGSWDKMLKLWSTDCNVDGDQSED 877

Query: 217 MCRQ------------------SFTGHISDINAVSFFPSGYAFATGSDDATCRLFDLRAD 258
             R                   + +GH   ++AV +    +   T S D + RL+DL   
Sbjct: 878 TERPSKKKKSAKSTTQTRVPVLTLSGHAEAVSAVRWL-DPHRVVTSSWDHSLRLWDLHTA 1054

Query: 259 QELLLYSHDNIICGITSVAFSKSGRLLLAGYDD 291
           Q+  L         +  VA+S    +L+ G  D
Sbjct: 1055QQTSLIQGSK---AVLDVAYSPLSHMLITGSAD 1144
>03395
          Length = 2795

 Score = 64.7 bits (156), Expect = 5e-11,   Method: Compositional matrix adjust.
 Identities = 49/168 (29%), Positives = 74/168 (44%), Gaps = 2/168 (1%)
 Frame = +2

Query: 51  LRGHLAKIYAMHWGYDSRLLVSASQDGKLIIWDSYTTNKMHAIPLRSSWVMTCAYAPSGN 110
           ++ H  K+ A+    + R  VSAS DG  IIWD   TN    I L ++      +     
Sbjct: 134 MKEHKGKVTAIQIHTNDRCCVSASTDGSTIIWD-LITNTRSQIVLANTLFKCVCFGGKDL 310

Query: 111 YVACGGLDNICSIYNLKTREGNVRVSRELPG-HTGYLSCCRFLDDGQIITSSG-DTTCAL 168
           ++   G D+    + +    G+  + REL G  TG ++      DGQ I + G D+   L
Sbjct: 311 HILTSGTDHKIGYWEV----GDGGLLRELEGSQTGAINTIDIDRDGQTILTGGEDSLLKL 478

Query: 169 WDIETGQQTTTFTGHSGDVMSLSLSPDLKTFVSGACDASSKLWDIRDG 216
           W    G+ T T  GHS  +    + P+    VSG  D +  +W   DG
Sbjct: 479 WRYNEGEVTHTGIGHSNQITKARICPNRHYIVSGGEDGALHIWKFPDG 622

 Score = 38.9 bits (89), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 37/193 (19%), Positives = 74/193 (38%), Gaps = 8/193 (4%)
 Frame = +2

Query: 156 QIITSSGDTTCALWDI--------ETGQQTTTFTGHSGDVMSLSLSPDLKTFVSGACDAS 207
           ++++  G+    +WDI          G        H G V ++ +  + +  VS + D S
Sbjct: 38  KLVSGGGEGQVRVWDIVKDMLTGKTRGDLVANMKEHKGKVTAIQIHTNDRCCVSASTDGS 217

Query: 208 SKLWDIRDGMCRQSFTGHISDINAVSFFPSGYAFATGSDDATCRLFDLRADQELLLYSHD 267
           + +WD+      Q    + +    V F        T   D     +++  D  LL     
Sbjct: 218 TIIWDLITNTRSQIVLAN-TLFKCVCFGGKDLHILTSGTDHKIGYWEV-GDGGLLRELEG 391

Query: 268 NIICGITSVAFSKSGRLLLAGYDDFNCSVWDALKGGRSGVLAGHDNRVSCLGVTDDGMAV 327
           +    I ++   + G+ +L G +D    +W   +G  +    GH N+++   +  +   +
Sbjct: 392 SQTGAINTIDIDRDGQTILTGGEDSLLKLWRYNEGEVTHTGIGHSNQITKARICPNRHYI 571

Query: 328 ATGSWDSFLRIWN 340
            +G  D  L IW 
Sbjct: 572 VSGGEDGALHIWK 610
>17602
          Length = 481

 Score = 63.9 bits (154), Expect = 8e-11,   Method: Compositional matrix adjust.
 Identities = 41/136 (30%), Positives = 63/136 (46%), Gaps = 4/136 (2%)
 Frame = +3

Query: 209 KLWDIRDGMCRQSFTGHISDINAVSFFPSGYAFATGSDDATCRLFDLRADQELL-LYSHD 267
           ++WD++ G C ++   H   + AV F   G    + S D  CR++D  + Q L  L   D
Sbjct: 3   RIWDVKTGKCLKTLPAHSDPVTAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLXTLIDDD 182

Query: 268 NIICGITSVAFSKSGRLLLAGYDDFNCSVWDALKGGRSGVLAGHDNRVSCLGV---TDDG 324
           N    ++ V FS +G+ +LA   D    +WD  KG       GH N   C+        G
Sbjct: 183 NP--PVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYVGHRNEKYCIFANFSVTGG 356

Query: 325 MAVATGSWDSFLRIWN 340
             + +GS D+ + IWN
Sbjct: 357 KWIVSGSEDNMVYIWN 404

 Score = 53.1 bits (126), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 44/158 (27%), Positives = 68/158 (43%), Gaps = 7/158 (4%)
 Frame = +3

Query: 168 LWDIETGQQTTTFTGHSGDVMSLSLSPDLKTFVSGACDASSKLWDIRDGMCRQSFTGHIS 227
           +WD++TG+   T   HS  V ++  + D    VS + D   ++WD   G C  +    I 
Sbjct: 6   IWDVKTGKCLKTLPAHSDPVTAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLXTL---ID 176

Query: 228 DINA----VSFFPSGYAFATGSDDATCRLFDLRADQELLLY-SHDNIICGITSVAFSKSG 282
           D N     V F P+G      + D T +L+D    + L  Y  H N    I +      G
Sbjct: 177 DDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYVGHRNEKYCIFANFSVTGG 356

Query: 283 RLLLAGYDDFNCSVWDALKGGRSGVLAGHDNR--VSCL 318
           + +++G +D    +W+ L  G S    G   R  V CL
Sbjct: 357 KWIVSGSEDNMVYIWNLLDQGDSTEATGSHRRGAVLCL 470

 Score = 40.0 bits (92), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 35/139 (25%), Positives = 60/139 (43%), Gaps = 5/139 (3%)
 Frame = +3

Query: 49  RTLRGHLAKIYAMHWGYDSRLLVSASQDGKLIIWDSYTTNKMHA-IPLRSSWVMTCAYAP 107
           +TL  H   + A+H+  D  L+VS+S DG   IWD+ +   +   I   +  V    ++P
Sbjct: 36  KTLPAHSDPVTAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLXTLIDDDNPPVSFVKFSP 215

Query: 108 SGNYVACGGLDNICSIYNLKTREGNVRVSRELPGHTGYLSC--CRFLDDG--QIITSSGD 163
           +G Y+    LDN   +++        +  +   GH     C    F   G   I++ S D
Sbjct: 216 NGKYILAATLDNTLKLWDYSKG----KCLKTYVGHRNEKYCIFANFSVTGGKWIVSGSED 383

Query: 164 TTCALWDIETGQQTTTFTG 182
               +W++     +T  TG
Sbjct: 384 NMVYIWNLLDQGDSTEATG 440

 Score = 39.3 bits (90), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 33/139 (23%), Positives = 60/139 (43%), Gaps = 4/139 (2%)
 Frame = +3

Query: 81  IWDSYTTNKMHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELP 140
           IWD  T   +  +P  S  V    +   G+ +     D +C I++  T  G   +   + 
Sbjct: 6   IWDVKTGKCLKTLPAHSDPVTAVHFNRDGSLIVSSSYDGLCRIWD--TASGQC-LXTLID 176

Query: 141 GHTGYLSCCRFLDDGQ-IITSSGDTTCALWDIETGQQTTTFTGHSGDVMSLSLSPDL--- 196
                +S  +F  +G+ I+ ++ D T  LWD   G+   T+ GH  +   +  +  +   
Sbjct: 177 DDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYVGHRNEKYCIFANFSVTGG 356

Query: 197 KTFVSGACDASSKLWDIRD 215
           K  VSG+ D    +W++ D
Sbjct: 357 KWIVSGSEDNMVYIWNLLD 413
>03387
          Length = 1891

 Score = 60.5 bits (145), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 54/169 (31%), Positives = 80/169 (47%), Gaps = 15/169 (8%)
 Frame = +1

Query: 154 DGQIITSSGDTTCALWDIETGQQT-------TTFTGHSGDVMSLS---LSPDLKTFVSGA 203
           +G ++++S D T  LWDI + Q+        T FTGH+  V  ++   L   L  F S A
Sbjct: 400 NGHLLSASDDHTICLWDINSTQRESRVVDAHTIFTGHTSVVEDVAWHLLHESL--FGSVA 573

Query: 204 CDASSKLWDIRDGMCRQS---FTGHISDINAVSFFP-SGYAFATGSDDATCRLFDLRADQ 259
            D    +WD R     +       H +++N +SF P S +  ATGS D T  L+DLR + 
Sbjct: 574 DDQKLMIWDTRSNTTSKPSHVVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLR-NL 750

Query: 260 ELLLYSHDNIICGITSVAFSKSGRLLLAGY-DDFNCSVWDALKGGRSGV 307
           +L L+S ++    I  V +S     +LA    D    VWD  K G   +
Sbjct: 751 KLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLHVWDLSKIGEEQL 897

 Score = 40.8 bits (94), Expect = 9e-04,   Method: Compositional matrix adjust.
 Identities = 50/213 (23%), Positives = 86/213 (40%), Gaps = 26/213 (12%)
 Frame = +1

Query: 51  LRGHLAKIYAMHWGYD-SRLLVSASQDGKLIIWDSYTTNK------MHAIPLRSSWVMTC 103
           L+GH  + Y + W  + +  L+SAS D  + +WD  +T +       H I    + V+  
Sbjct: 349 LKGHQKEGYGLSWNPNLNGHLLSASDDHTICLWDINSTQRESRVVDAHTIFTGHTSVVED 528

Query: 104 AYAPSGNYVACGGLDNICSIYNLKTREGNV-RVSRELPGHTGYLSCCRFLDDGQII--TS 160
                 +    G + +   +    TR     + S  +  HT  ++C  F    + I  T 
Sbjct: 529 VAWHLLHESLFGSVADDQKLMIWDTRSNTTSKPSHVVDAHTAEVNCLSFNPYSEFILATG 708

Query: 161 SGDTTCALWDIETGQ-QTTTFTGHSGDVMSLSLSPDLKTFV-SGACDASSKLWDI----- 213
           S D T ALWD+   + +  +F  H  ++  +  SP  +T + S   D    +WD+     
Sbjct: 709 SADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLHVWDLSKIGE 888

Query: 214 -------RDGMCRQSFT--GHISDINAVSFFPS 237
                   DG     F   GH + I+  S+ P+
Sbjct: 889 EQLPEDAEDGPPELLFIHGGHTAKISDFSWNPN 987
>10162
          Length = 1629

 Score = 58.9 bits (141), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 65/300 (21%), Positives = 116/300 (38%), Gaps = 19/300 (6%)
 Frame = +3

Query: 58  IYAMHWGYDSRLLVSASQDGKLIIWD--SYTTNKMHAIPLRSSWVMTCAYAPSGNYVACG 115
           I  + W   + +L++ +Q G++ +W   S   +KM  +       +     P+G YV  G
Sbjct: 36  ITWLQWHGGAHVLLAGTQGGEVWLWQVPSQDYSKMKMLQSHGQPSLCGKILPNGKYVCVG 215

Query: 116 GLDNICSIYNLKTR------EGNVRVSRELPGHTGYLSCCRFLDDGQIITSSGDTTCALW 169
             D +  +++LKT       + +V    E+P                             
Sbjct: 216 YSDGVVKLWDLKTGTAVHTWQHSVMPEEEMPERNSSDE---------------------- 329

Query: 170 DIETGQQTTTFTGHSGDVMSLSLSPDLKTFVSGACDASSKLWDIRDGMCRQSFTGHISD- 228
             +  +        +  ++ +  S D    +SG  DA++K++++  G    +F    S  
Sbjct: 330 -EDGEEVEVEREEDTVAILCVDCSADNALIMSGCADATAKVFNVSSGKLXSAFNCAASQD 506

Query: 229 -------INAVSFFPSGYAFATGSDDATCRLFDLRADQELLLYSHDNIICGITSVAFSKS 281
                  + +V+F P     AT ++  + +++DL        + H   +C +    +S S
Sbjct: 507 SQDKDNSVESVAFCPVSPYAATATNSGSVQVWDLPTSVARHSFQHPEGVCKLQ---WSSS 677

Query: 282 GRLLLAGYDDFNCSVWDALKGGRSGVLAGHDNRVSCL---GVTDDGMAVATGSWDSFLRI 338
             LL     D    VWDA  G    VL GH  R SC+    VT DG  + +GS D   R+
Sbjct: 678 TALLYTACLDGVMRVWDARSGASKAVLTGH-ARNSCILDFDVTRDGTCLVSGSEDGTARV 854
>01805
          Length = 2124

 Score = 57.0 bits (136), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 60/257 (23%), Positives = 109/257 (42%), Gaps = 35/257 (13%)
 Frame = -1

Query: 77  GKLIIWDSYTTNK------------MHAIPLRSSWVMTCAY--APSGNYVACGGLDNICS 122
           G L + D Y  N+            + + PL   W+    Y  AP GN+VA G ++ +  
Sbjct: 861 GDLSVLDVYVYNEDNNQLYVHHDYLLSSFPLALEWLNFDGYDNAP-GNFVAIGSMEPVIE 685

Query: 123 IYNLKTREG----------------NVRVSRELPGHTGYLSCCRFLDDGQ--IITSSGDT 164
           I++L   E                  ++    + GHT  +    +  + +  + ++S DT
Sbjct: 684 IWDLDIMESVGPTLTLGSKPKKTKKKMKQKESVTGHTQAVLDLSWNRNARHVLASASADT 505

Query: 165 TCALWDIETGQQTTTFTGHSGDVMSLSLSP-DLKTFVSGACDASSKLWDIRDG-MCRQSF 222
           T ALWD+  G+    FT HS +V   +  P + +T ++G+ D + K+ D R    C +S+
Sbjct: 504 TVALWDLSEGKMAMNFTQHSREVQCCNWHPQEEQTLLTGSFDNTVKVVDCRSAETCHKSW 325

Query: 223 TGHISDINAVSFFPSGYAFATGSDDATCRLFDLRADQELL-LYSHDNIICGITSVAFSKS 281
           T       AV    +       +D      FD+R ++ +  + +H + + G+     S+ 
Sbjct: 324 TVEGEVEKAVWNHHNPLQLLACTDKGMVYCFDIRHEKPVFSVGAHSSCVTGV--CLSSQI 151

Query: 282 GRLLLAGYDDFNCSVWD 298
             L++   +D    VWD
Sbjct: 150 PGLMITTSEDKTMKVWD 100
>03156
          Length = 1014

 Score = 53.5 bits (127), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 43/195 (22%), Positives = 78/195 (40%), Gaps = 11/195 (5%)
 Frame = +1

Query: 157 IITSSGDTTCALWDIETGQQTTTFTGHSGDVMSLSLSPDLKTFVSGACDASSKLWDIRDG 216
           + ++S D T  +W          F GH   V ++ L+ D     SG+ D + ++WD+  G
Sbjct: 100 MFSASRDKTIKMWQRGNSHSIRDFIGHDMVVTAIHLNTDNTLLCSGSRDNTVRIWDVETG 279

Query: 217 MCRQSFTGHISDINAVSFFPSGYAFATGSDDATCRLFDLRADQELLLYSHDNII---CGI 273
            C +      + +  V + P  +      +D   R++D R    +  ++    I   C +
Sbjct: 280 ACLRQNNIPQNLVTDVKWLPGSHLIIQAGEDKEVRIYDSRTLGIVRSFTKKQYIQMSCDV 459

Query: 274 TSVAFSKSGRLLLAGYDDF-----NCSVWDALKGGRSGVLAGHDNRV-SCLGV--TDDGM 325
           T+      G+  L   + F       ++W    G       GH   + +CL +    D  
Sbjct: 460 TA-----DGQFCLTCSNGFGGNGCEATLWQLSDGSIQNEFKGHREAIEACLFLPSNQDMT 624

Query: 326 AVATGSWDSFLRIWN 340
            +AT S D  +R+WN
Sbjct: 625 LIATASRDCSVRVWN 669

 Score = 53.1 bits (126), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 46/187 (24%), Positives = 76/187 (40%), Gaps = 11/187 (5%)
 Frame = +1

Query: 49  RTLRGHLAKIYAMHWGYDSRLLVSASQDGKLIIWDSYTTNKMHAIPLRSSWVMTCAYAPS 108
           R   GH   + A+H   D+ LL S S+D  + IWD  T   +    +  + V    + P 
Sbjct: 163 RDFIGHDMVVTAIHLNTDNTLLCSGSRDNTVRIWDVETGACLRQNNIPQNLVTDVKWLPG 342

Query: 109 GNYVACGGLDNICSIYNLKTREGNVRVSRELPGHTGYLSCCRFLDDGQI-ITSS---GDT 164
            + +   G D    IY+ +T    + + R           C    DGQ  +T S   G  
Sbjct: 343 SHLIIQAGEDKEVRIYDSRT----LGIVRSFTKKQYIQMSCDVTADGQFCLTCSNGFGGN 510

Query: 165 TC--ALWDIETGQQTTTFTGHSGDVMSLSLSP---DLKTFVSGACDASSKLWDI--RDGM 217
            C   LW +  G     F GH   + +    P   D+    + + D S ++W++  ++ +
Sbjct: 511 GCEATLWQLSDGSIQNEFKGHREAIEACLFLPSNQDMTLIATASRDCSVRVWNMFTKECV 690

Query: 218 CRQSFTG 224
           C Q+F G
Sbjct: 691 CEQNFEG 711

 Score = 33.5 bits (75), Expect = 0.13,   Method: Compositional matrix adjust.
 Identities = 26/129 (20%), Positives = 52/129 (40%), Gaps = 1/129 (0%)
 Frame = +1

Query: 172 ETGQQTTTFTGHSGDVMSLSLSPDLKTFVSGACDASSKLWDIRDGMCRQSFTGHISDINA 231
           + G+    +TGH  ++  +          S + D + K+W   +    + F GH   + A
Sbjct: 19  KMGRLEDRWTGHDREITKVCYGASCNGMFSASRDKTIKMWQRGNSHSIRDFIGHDMVVTA 198

Query: 232 VSFFPSGYAFATGSDDATCRLFDLRADQELLLYSHDNIICG-ITSVAFSKSGRLLLAGYD 290
           +          +GS D T R++D+     L     +NI    +T V +     L++   +
Sbjct: 199 IHLNTDNTLLCSGSRDNTVRIWDVETGACL---RQNNIPQNLVTDVKWLPGSHLIIQAGE 369

Query: 291 DFNCSVWDA 299
           D    ++D+
Sbjct: 370 DKEVRIYDS 396
>01327
          Length = 2215

 Score = 53.1 bits (126), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 46/187 (24%), Positives = 76/187 (40%), Gaps = 11/187 (5%)
 Frame = +3

Query: 49  RTLRGHLAKIYAMHWGYDSRLLVSASQDGKLIIWDSYTTNKMHAIPLRSSWVMTCAYAPS 108
           R   GH   + A+H   D+ LL S S+D  + IWD  T   +    +  + V    + P 
Sbjct: 273 RDFIGHDMVVTAIHLNTDNTLLCSGSRDNTVRIWDVETGACLRQNNIPQNLVTDVKWLPG 452

Query: 109 GNYVACGGLDNICSIYNLKTREGNVRVSRELPGHTGYLSCCRFLDDGQI-ITSS---GDT 164
            + +   G D    IY+ +T    + + R           C    DGQ  +T S   G  
Sbjct: 453 SHLIIQAGEDKEVRIYDSRT----LGIVRSFTKKQYIQMSCDVTADGQFCLTCSNGFGGN 620

Query: 165 TC--ALWDIETGQQTTTFTGHSGDVMSLSLSP---DLKTFVSGACDASSKLWDI--RDGM 217
            C   LW +  G     F GH   + +    P   D+    + + D S ++W++  ++ +
Sbjct: 621 GCEATLWQLSDGSIQNEFKGHREAIEACLFLPSNQDMTLIATASRDCSVRVWNMFTKECV 800

Query: 218 CRQSFTG 224
           C Q+F G
Sbjct: 801 CEQNFEG 821

 Score = 44.3 bits (103), Expect = 7e-05,   Method: Compositional matrix adjust.
 Identities = 32/151 (21%), Positives = 63/151 (41%), Gaps = 1/151 (0%)
 Frame = +3

Query: 150 RFLDDGQIITSSGDTTCALWDIETGQQTTTFTGHSGDVMSLSLSPDLKTFVSGACDASSK 209
           R +  G  ++ S D +  L+D + G+    +TGH  ++  +          S + D + K
Sbjct: 63  RSIQPGLCLSGSKDKSVVLYDYQNGRLEDRWTGHDREITKVCYGASCNGMFSASRDKTIK 242

Query: 210 LWDIRDGMCRQSFTGHISDINAVSFFPSGYAFATGSDDATCRLFDLRADQELLLYSHDNI 269
           +W   +    + F GH   + A+          +GS D T R++D+     L     +NI
Sbjct: 243 MWQRGNSHSIRDFIGHDMVVTAIHLNTDNTLLCSGSRDNTVRIWDVETGACL---RQNNI 413

Query: 270 ICG-ITSVAFSKSGRLLLAGYDDFNCSVWDA 299
               +T V +     L++   +D    ++D+
Sbjct: 414 PQNLVTDVKWLPGSHLIIQAGEDKEVRIYDS 506

 Score = 30.0 bits (66), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 25/99 (25%), Positives = 42/99 (42%), Gaps = 1/99 (1%)
 Frame = +3

Query: 243 TGSDDATCRLFDLRADQ-ELLLYSHDNIICGITSVAFSKSGRLLLAGYDDFNCSVWDALK 301
           +GS D +  L+D +  + E     HD     IT V +  S   + +   D    +W    
Sbjct: 90  SGSKDKSVVLYDYQNGRLEDRWTGHDR---EITKVCYGASCNGMFSASRDKTIKMWQRGN 260

Query: 302 GGRSGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLRIWN 340
                   GHD  V+ + +  D   + +GS D+ +RIW+
Sbjct: 261 SHSIRDFIGHDMVVTAIHLNTDNTLLCSGSRDNTVRIWD 377
>02090
          Length = 1841

 Score = 53.1 bits (126), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 43/156 (27%), Positives = 68/156 (43%), Gaps = 2/156 (1%)
 Frame = -3

Query: 143  TGYLSCCRFLDDGQIITSSGDTTCALWDI--ETGQQTTTFTGHSGDVMSLSLSPDLKTFV 200
            +G  SCCR    G   +    +T ++WD+   T +     T  +    +L++SPD K   
Sbjct: 1746 SGPSSCCR---TGAR*SWREASTLSIWDLATPTPRIKAELTSSAPACYALAISPDGKVCF 1576

Query: 201  SGACDASSKLWDIRDGMCRQSFTGHISDINAVSFFPSGYAFATGSDDATCRLFDLRADQE 260
            S   D +  +WD+ +    + F GH    + +   P G    TG  D T R +DLR  ++
Sbjct: 1575 SCCSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISPDGTKLWTGGLDNTVRSWDLREGRQ 1396

Query: 261  LLLYSHDNIICGITSVAFSKSGRLLLAGYDDFNCSV 296
              L  HD     I S+ +  +G  L  G +  N  V
Sbjct: 1395 --LQQHD-FSSQIFSLGYCPTGEWLAVGMESSNVEV 1297

 Score = 37.0 bits (84), Expect = 0.010,   Method: Compositional matrix adjust.
 Identities = 19/66 (28%), Positives = 33/66 (50%)
 Frame = -3

Query: 275  SVAFSKSGRLLLAGYDDFNCSVWDALKGGRSGVLAGHDNRVSCLGVTDDGMAVATGSWDS 334
            ++A S  G++  +   D N +VWD           GH +  SC+ ++ DG  + TG  D+
Sbjct: 1611 ALAISPDGKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISPDGTKLWTGGLDN 1432

Query: 335  FLRIWN 340
             +R W+
Sbjct: 1431 TVRSWD 1414

 Score = 32.3 bits (72), Expect = 0.30,   Method: Compositional matrix adjust.
 Identities = 24/97 (24%), Positives = 38/97 (39%)
 Frame = -3

Query: 46   RTRRTLRGHLAKIYAMHWGYDSRLLVSASQDGKLIIWDSYTTNKMHAIPLRSSWVMTCAY 105
            R +  L       YA+    D ++  S   DG + +WD +    +      +        
Sbjct: 1653 RIKAELTSSAPACYALAISPDGKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGASCIDI 1474

Query: 106  APSGNYVACGGLDNICSIYNLKTREGNVRVSRELPGH 142
            +P G  +  GGLDN    ++L  REG     R+L  H
Sbjct: 1473 SPDGTKLWTGGLDNTVRSWDL--REG-----RQLQQH 1384

 Score = 30.0 bits (66), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 30/130 (23%), Positives = 60/130 (46%), Gaps = 3/130 (2%)
 Frame = -3

Query: 45   MRTRRTLRGH--LAKIYAMHWGYDSRLLVSASQDGKLIIWDSYTTNKMHAIPLRSSWVMT 102
            +R  R L+ H   ++I+++ +      L    +   + +      +K + + L  S V++
Sbjct: 1413 LREGRQLQQHDFSSQIFSLGYCPTGEWLAVGMESSNVEVLHHSKPDK-YQLHLHESCVLS 1237

Query: 103  CAYAPSGNYVACGGLDNICSIYNLKTREG-NVRVSRELPGHTGYLSCCRFLDDGQIITSS 161
              +A  G +    G DN+ + +  +T  G ++  S+E    +  LSC    DD  I+T S
Sbjct: 1236 LKFAYCGKWFVSTGKDNLLNAW--RTPYGASIFQSKE---SSSVLSCDIAADDKYIVTGS 1072

Query: 162  GDTTCALWDI 171
            GD    L+++
Sbjct: 1071 GDKKATLYEV 1042
>26107
          Length = 1338

 Score = 52.8 bits (125), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 45/150 (30%), Positives = 68/150 (45%), Gaps = 1/150 (0%)
 Frame = -3

Query: 153  DDGQIITSSGDTTCALWDIETGQQTTTFTGHSGDVMSLSLSPDLKTF-VSGACDASSKLW 211
            +D Q +T+SGD T ALWD+ET  + TTF GH   V S++  P       SGA D    LW
Sbjct: 1054 NDSQCLTASGDQTVALWDVETTTKVTTFIGHKCSVRSVASCPSSPAQCASGARDGHIMLW 875

Query: 212  DIRDGMCRQSFTGHISDINAVSFFPSGYAFATGSDDATCRLFDLRADQELLLYSHDNIIC 271
            D R    R+      S ++ V    SG+     S  A  R     A  + ++ +  ++ C
Sbjct: 874  DSRVNKKREHQP--CSQVHQVC-PQSGHQ----SKPAKHRRIHRAAGPKGVMDTQQSVTC 716

Query: 272  GITSVAFSKSGRLLLAGYDDFNCSVWDALK 301
                V +     ++ +G +D    +WD  K
Sbjct: 715  ----VLYQTDNLIISSGANDGCVKMWDTRK 638

 Score = 40.0 bits (92), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 53/254 (20%), Positives = 95/254 (37%), Gaps = 52/254 (20%)
 Frame = -3

Query: 72  SASQDGKLIIWDSYTTNKMHAIP--------------------------------LRSSW 99
           S ++DG +++WDS    K    P                                + +  
Sbjct: 907 SGARDGHIMLWDSRVNKKREHQPCSQVHQVCPQSGHQSKPAKHRRIHRAAGPKGVMDTQQ 728

Query: 100 VMTCAYAPSGNYVACGGLDNIC-SIYNLKTREGNVRVSRELPGHT-----------GYLS 147
            +TC    + N +   G ++ C  +++ +    N   S  +P HT           G ++
Sbjct: 727 SVTCVLYQTDNLIISSGANDGCVKMWDTRKWYTNTTTSLPVPVHTFDYPGHMRRLKGIVT 548

Query: 148 CCRFLDDGQIITSSGDTTCALWDIETGQ----QTTTFTGHSGDVMSL--SLSPDLKTFVS 201
            C      Q+  S  D     + +  GQ    Q   + GH  D   +  ++SPD K  +S
Sbjct: 547 MCMDPWKSQLFVSYTDNKVYRYQL-AGQYREPQEYVYAGHRNDTFFVRCAISPDGKYLLS 371

Query: 202 GACDASSKLWDIRDGMCRQSF-TGHISDINAVSFFPSGY-AFATGSDDATCRLFDLRADQ 259
           G+   +  +W++     R  F  GH  D++AV +  +     AT SDD + R++   A +
Sbjct: 370 GSGRNTGVIWEVDKPNKRPLFLIGHTEDVSAVDWCSTDVCKLATVSDDRSLRIWRPDARE 191

Query: 260 ELLLYSHDNIICGI 273
               ++ D  I G 
Sbjct: 190 R---HTEDPTISGF 158

 Score = 37.4 bits (85), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 75/319 (23%), Positives = 118/319 (36%), Gaps = 32/319 (10%)
 Frame = -3

Query: 53   GHLAKIYAMHWGYDSRLLVSASQDGKLIIWDSYTTNKM-----HAIPLRSSWVMTCAYAP 107
             H   ++   W  +    ++AS D  + +WD  TT K+     H   +RS  V +C  +P
Sbjct: 1093 AHNNAVFDYSWISNDSQCLTASGDQTVALWDVETTTKVTTFIGHKCSVRS--VASCPSSP 920

Query: 108  SGNYVACGGLDNICSIYNL---KTREGNV--RVSRELP--GHTGYLSCCRFLDDGQIITS 160
            +    A G  D    +++    K RE     +V +  P  GH    +  R +        
Sbjct: 919  AQ--CASGARDGHIMLWDSRVNKKREHQPCSQVHQVCPQSGHQSKPAKHRRIHRAAGPKG 746

Query: 161  SGDTTCALWDIETGQQTTTFTGHSGDVMSLSLSPDLKTFVSGACDASSKLWDIRDGMCRQ 220
              DT          QQ+ T   +  D + +S         SGA D   K+WD R      
Sbjct: 745  VMDT----------QQSVTCVLYQTDNLIIS---------SGANDGCVKMWDTRKWYTNT 623

Query: 221  S-----------FTGHISDINAVSFF---P-SGYAFATGSDDATCRLF---DLRADQELL 262
            +           + GH+  +  +      P     F + +D+   R       R  QE +
Sbjct: 622  TTSLPVPVHTFDYPGHMRRLKGIVTMCMDPWKSQLFVSYTDNKVYRYQLAGQYREPQEYV 443

Query: 263  LYSHDNIICGITSVAFSKSGRLLLAGYDDFNCSVWDALKGGRSGV-LAGHDNRVSCLG-V 320
               H N    +   A S  G+ LL+G       +W+  K  +  + L GH   VS +   
Sbjct: 442  YAGHRNDTFFV-RCAISPDGKYLLSGSGRNTGVIWEVDKPNKRPLFLIGHTEDVSAVDWC 266

Query: 321  TDDGMAVATGSWDSFLRIW 339
            + D   +AT S D  LRIW
Sbjct: 265  STDVCKLATVSDDRSLRIW 209

 Score = 32.3 bits (72), Expect = 0.27,   Method: Compositional matrix adjust.
 Identities = 36/172 (20%), Positives = 74/172 (43%), Gaps = 5/172 (2%)
 Frame = -3

Query: 174  GQQTTT---FTGHSGDVMSLSLSPDLKTFVSGACDASSKLWDIRDGMCRQSFTGHISDIN 230
            GQ + T   +  H+  V   S   +    ++ + D +  LWD+       +F GH   + 
Sbjct: 1126 GQDSPTVHRWXAHNNAVFDYSWISNDSQCLTASGDQTVALWDVETTTKVTTFIGHKCSVR 947

Query: 231  AVSFFPSGYAF-ATGSDDATCRLFDLRADQELLLYSHDNIICGITSVAFSKSG-RLLLAG 288
            +V+  PS  A  A+G+ D    L+D R +++      ++  C        +SG +   A 
Sbjct: 946  SVASCPSSPAQCASGARDGHIMLWDSRVNKK-----REHQPCSQVHQVCPQSGHQSKPAK 782

Query: 289  YDDFNCSVWDALKGGRSGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLRIWN 340
            +   +         G  GV+    + V+C+    D + +++G+ D  +++W+
Sbjct: 781  HRRIH------RAAGPKGVMDTQQS-VTCVLYQTDNLIISSGANDGCVKMWD 647
>12574
          Length = 521

 Score = 52.4 bits (124), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 32/119 (26%), Positives = 54/119 (45%), Gaps = 1/119 (0%)
 Frame = +3

Query: 128 TREGNVRVSRELPGHTGYLSCCRFLDDGQ-IITSSGDTTCALWDIETGQQTTTFTGHSGD 186
           T++    +   L GHT  LS  +F  +G  + +SS D    +W    G+   T  GH   
Sbjct: 141 TQKPTYTLKFTLAGHTKALSAVKFSPNGDWLASSSADKLIKIWGAYDGKFEKTIAGHKLG 320

Query: 187 VMSLSLSPDLKTFVSGACDASSKLWDIRDGMCRQSFTGHISDINAVSFFPSGYAFATGS 245
           +  ++ S D K   S + D + K+W+   G C ++  GH + +   +F P      +GS
Sbjct: 321 LSDVAWSSDSKLLCSASDDKTLKIWEFSTGKCMKTLKGHSNYVFCCNFNPQSNLIVSGS 497

 Score = 47.0 bits (110), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 25/77 (32%), Positives = 37/77 (48%)
 Frame = +3

Query: 41  GRIQMRTRRTLRGHLAKIYAMHWGYDSRLLVSASQDGKLIIWDSYTTNKMHAIPLRSSWV 100
           G    +  +T+ GH   +  + W  DS+LL SAS D  L IW+  T   M  +   S++V
Sbjct: 270 GAYDGKFEKTIAGHKLGLSDVAWSSDSKLLCSASDDKTLKIWEFSTGKCMKTLKGHSNYV 449

Query: 101 MTCAYAPSGNYVACGGL 117
             C + P  N +  G L
Sbjct: 450 FCCNFNPQSNLIVSGSL 500

 Score = 43.1 bits (100), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 30/114 (26%), Positives = 50/114 (43%), Gaps = 1/114 (0%)
 Frame = +3

Query: 219 RQSFTGHISDINAVSFFPSGYAFATGSDDATCRLFDLRADQ-ELLLYSHDNIICGITSVA 277
           + +  GH   ++AV F P+G   A+ S D   +++     + E  +  H     G++ VA
Sbjct: 165 KFTLAGHTKALSAVKFSPNGDWLASSSADKLIKIWGAYDGKFEKTIAGHK---LGLSDVA 335

Query: 278 FSKSGRLLLAGYDDFNCSVWDALKGGRSGVLAGHDNRVSCLGVTDDGMAVATGS 331
           +S   +LL +  DD    +W+   G     L GH N V C         + +GS
Sbjct: 336 WSSDSKLLCSASDDKTLKIWEFSTGKCMKTLKGHSNYVFCCNFNPQSNLIVSGS 497

 Score = 36.6 bits (83), Expect = 0.017,   Method: Compositional matrix adjust.
 Identities = 26/113 (23%), Positives = 44/113 (38%)
 Frame = +3

Query: 48  RRTLRGHLAKIYAMHWGYDSRLLVSASQDGKLIIWDSYTTNKMHAIPLRSSWVMTCAYAP 107
           + TL GH   + A+ +  +   L S+S D  + IW +Y       I      +   A++ 
Sbjct: 165 KFTLAGHTKALSAVKFSPNGDWLASSSADKLIKIWGAYDGKFEKTIAGHKLGLSDVAWSS 344

Query: 108 SGNYVACGGLDNICSIYNLKTREGNVRVSRELPGHTGYLSCCRFLDDGQIITS 160
               +     D    I+   T     +  + L GH+ Y+ CC F     +I S
Sbjct: 345 DSKLLCSASDDKTLKIWEFSTG----KCMKTLKGHSNYVFCCNFNPQSNLIVS 491

 Score = 36.2 bits (82), Expect = 0.022,   Method: Compositional matrix adjust.
 Identities = 21/93 (22%), Positives = 42/93 (45%), Gaps = 1/93 (1%)
 Frame = +3

Query: 179 TFTGHSGDVMSLSLSPDLKTFVSGACDASSKLWDIRDGMCRQSFTGHISDINAVSFFPSG 238
           T  GH+  + ++  SP+     S + D   K+W   DG   ++  GH   ++ V++    
Sbjct: 171 TLAGHTKALSAVKFSPNGDWLASSSADKLIKIWGAYDGKFEKTIAGHKLGLSDVAWSSDS 350

Query: 239 YAFATGSDDATCRLFDLRADQEL-LLYSHDNII 270
               + SDD T ++++    + +  L  H N +
Sbjct: 351 KLLCSASDDKTLKIWEFSTGKCMKTLKGHSNYV 449

 Score = 31.2 bits (69), Expect = 0.58,   Method: Compositional matrix adjust.
 Identities = 19/69 (27%), Positives = 32/69 (46%)
 Frame = +3

Query: 272 GITSVAFSKSGRLLLAGYDDFNCSVWDALKGGRSGVLAGHDNRVSCLGVTDDGMAVATGS 331
            +++V FS +G  L +   D    +W A  G     +AGH   +S +  + D   + + S
Sbjct: 192 ALSAVKFSPNGDWLASSSADKLIKIWGAYDGKFEKTIAGHKLGLSDVAWSSDSKLLCSAS 371

Query: 332 WDSFLRIWN 340
            D  L+IW 
Sbjct: 372 DDKTLKIWE 398
>19498
          Length = 903

 Score = 52.0 bits (123), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 36/139 (25%), Positives = 62/139 (44%), Gaps = 19/139 (13%)
 Frame = -1

Query: 134 RVSRELPGHTGYLSCCRFLDDGQIITSSGD-TTCALWDIETG-----------------Q 175
           RV  ++  H G ++C R+ ++G+ + S GD     +W I  G                 +
Sbjct: 813 RVLCQMDSHLGCVNCVRWSENGKFLASGGDDKLIMIWQISRGFGSGKSFGSNVTILEHWR 634

Query: 176 QTTTFTGHSGDVMSLSLSPDLKTFVSGACDASSKLWD-IRDGMCRQSFTGHISDINAVSF 234
              T  GH+GDV+ L+ SP      S + D +  +W+ ++         GH   +  V++
Sbjct: 633 SVATLRGHAGDVLDLAWSPQDLWLASCSVDNTIVVWNALKFSEQVAVIRGHAGMVKGVTW 454

Query: 235 FPSGYAFATGSDDATCRLF 253
            P G   A+ SDD T R++
Sbjct: 453 DPVGRYLASQSDDKTLRVW 397

 Score = 33.5 bits (75), Expect = 0.14,   Method: Compositional matrix adjust.
 Identities = 19/80 (23%), Positives = 35/80 (43%), Gaps = 1/80 (1%)
 Frame = -1

Query: 46  RTRRTLRGHLAKIYAMHWGYDSRLLVSASQDGKLIIWDSYT-TNKMHAIPLRSSWVMTCA 104
           R+  TLRGH   +  + W      L S S D  +++W++   + ++  I   +  V    
Sbjct: 636 RSVATLRGHAGDVLDLAWSPQDLWLASCSVDNTIVVWNALKFSEQVAVIRGHAGMVKGVT 457

Query: 105 YAPSGNYVACGGLDNICSIY 124
           + P G Y+A    D    ++
Sbjct: 456 WDPVGRYLASQSDDKTLRVW 397

 Score = 33.1 bits (74), Expect = 0.16,   Method: Compositional matrix adjust.
 Identities = 31/135 (22%), Positives = 59/135 (43%), Gaps = 18/135 (13%)
 Frame = -1

Query: 105 YAPSGNYVACGGLDNICSIYNL-------KTREGNVRVSRE------LPGHTG-YLSCCR 150
           ++ +G ++A GG D +  I+ +       K+   NV +         L GH G  L    
Sbjct: 762 WSENGKFLASGGDDKLIMIWQISRGFGSGKSFGSNVTILEHWRSVATLRGHAGDVLDLAW 583

Query: 151 FLDDGQIITSSGDTTCALWD-IETGQQTTTFTGHSGDVMSLSLSPDLKTFVSGACDASSK 209
              D  + + S D T  +W+ ++  +Q     GH+G V  ++  P  +   S + D + +
Sbjct: 582 SPQDLWLASCSVDNTIVVWNALKFSEQVAVIRGHAGMVKGVTWDPVGRYLASQSDDKTLR 403

Query: 210 LW---DIRDGMCRQS 221
           +W   D ++  C +S
Sbjct: 402 VWRTSDWKEETCVKS 358
>13278
          Length = 870

 Score = 49.7 bits (117), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 30/100 (30%), Positives = 48/100 (48%)
 Frame = +1

Query: 157 IITSSGDTTCALWDIETGQQTTTFTGHSGDVMSLSLSPDLKTFVSGACDASSKLWDIRDG 216
           + ++S D+T  LW++E G    T T H   V S++ SPD K   SG+ D    +W+++ G
Sbjct: 121 LASASFDSTVRLWEVERGLCLHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNVQTG 300

Query: 217 MCRQSFTGHISDINAVSFFPSGYAFATGSDDATCRLFDLR 256
               S+ G    I  V +   G      + D +  + DLR
Sbjct: 301 SLVHSYKG-TGGIFEVCWNHRGDKVGASASDGSVFVLDLR 417

 Score = 37.7 bits (86), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 19/62 (30%), Positives = 32/62 (51%)
 Frame = +1

Query: 67  SRLLVSASQDGKLIIWDSYTTNKMHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNL 126
           S +L SAS D  + +W+      +H +      V + A++P G Y+A G  D    I+N+
Sbjct: 112 SLILASASFDSTVRLWEVERGLCLHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNV 291

Query: 127 KT 128
           +T
Sbjct: 292 QT 297

 Score = 31.6 bits (70), Expect = 0.49,   Method: Compositional matrix adjust.
 Identities = 24/102 (23%), Positives = 44/102 (43%), Gaps = 9/102 (8%)
 Frame = +1

Query: 210 LWDIRDGMCRQSFTGHISDINAVSFFPSG---------YAFATGSDDATCRLFDLRADQE 260
           +W +    C         +I  + + P+G            A+ S D+T RL+++  ++ 
Sbjct: 1   IWSMGKDSCIHDLQLTTKEIYTIKWSPTGPGTSNPNTSLILASASFDSTVRLWEV--ERG 174

Query: 261 LLLYSHDNIICGITSVAFSKSGRLLLAGYDDFNCSVWDALKG 302
           L L++       + SVAFS  G+ L +G  D    +W+   G
Sbjct: 175 LCLHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNVQTG 300
>12960
          Length = 550

 Score = 49.3 bits (116), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 37/147 (25%), Positives = 57/147 (38%), Gaps = 9/147 (6%)
 Frame = +2

Query: 120 ICSIYNLKTREGNVRVSRELPGHTGYLSCC--------RF-LDDGQIITSSGDTTCALWD 170
           + S++N      N  +  ELP        C        RF +D    +T   D +  LW+
Sbjct: 80  VLSVFNKTHSVQNTNMKFELPDRKEVTINCKQQAVRAVRFSVDSRYCMTCGSDKSVKLWN 259

Query: 171 IETGQQTTTFTGHSGDVMSLSLSPDLKTFVSGACDASSKLWDIRDGMCRQSFTGHISDIN 230
                   T+ GH  +V+    S D     SG  D +  L+D+  G   + +  H   +N
Sbjct: 260 PHRELFLKTYIGHGHEVLDAQGSGDNSQICSGGIDKTVVLFDVASGQALRKYRDHAGTVN 439

Query: 231 AVSFFPSGYAFATGSDDATCRLFDLRA 257
            V F        +GS D T R +D R+
Sbjct: 440 CVKFNEESTVILSGSLDNTVRAWDTRS 520

 Score = 35.0 bits (79), Expect = 0.044,   Method: Compositional matrix adjust.
 Identities = 26/112 (23%), Positives = 48/112 (42%)
 Frame = +2

Query: 187 VMSLSLSPDLKTFVSGACDASSKLWDIRDGMCRQSFTGHISDINAVSFFPSGYAFATGSD 246
           V ++  S D +  ++   D S KLW+    +  +++ GH  ++             +G  
Sbjct: 182 VRAVRFSVDSRYCMTCGSDKSVKLWNPHRELFLKTYIGHGHEVLDAQGSGDNSQICSGGI 361

Query: 247 DATCRLFDLRADQELLLYSHDNIICGITSVAFSKSGRLLLAGYDDFNCSVWD 298
           D T  LFD+ + Q L  Y   +    +  V F++   ++L+G  D     WD
Sbjct: 362 DKTVVLFDVASGQALRKYR--DHAGTVNCVKFNEESTVILSGSLDNTVRAWD 511
>21105
          Length = 650

 Score = 48.5 bits (114), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 29/100 (29%), Positives = 45/100 (45%), Gaps = 4/100 (4%)
 Frame = +1

Query: 158 ITSSGDTTCALWDIETGQQTTTFTGHSGDVMSLSLSPDLKTFVSGACDASSKLWDIRDGM 217
           IT+  D     +D  TG+       H   V SL++ P+    +SG+ D S +LW++    
Sbjct: 112 ITAHEDRHIRFFDNNTGKLIHAMVAHLDSVTSLAVDPNGLYLLSGSHDCSIRLWNLDSKT 291

Query: 218 CRQSFTGHISD----INAVSFFPSGYAFATGSDDATCRLF 253
           C Q  T H       I+ V+F P     A+   DA  ++F
Sbjct: 292 CVQEITSHRKKFDESIHDVAFHPQKPYIASAGADALAKVF 411

 Score = 28.5 bits (62), Expect = 4.0,   Method: Compositional matrix adjust.
 Identities = 15/61 (24%), Positives = 31/61 (50%)
 Frame = +1

Query: 69  LLVSASQDGKLIIWDSYTTNKMHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKT 128
           + ++A +D  +  +D+ T   +HA+      V + A  P+G Y+  G  D    ++NL +
Sbjct: 106 ITITAHEDRHIRFFDNNTGKLIHAMVAHLDSVTSLAVDPNGLYLLSGSHDCSIRLWNLDS 285

Query: 129 R 129
           +
Sbjct: 286 K 288
>37180
          Length = 681

 Score = 47.0 bits (110), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 24/78 (30%), Positives = 40/78 (51%), Gaps = 1/78 (1%)
 Frame = +1

Query: 180 FTGHSGDVMSLSLSPDLKTFVSGACDASSKLWDIRD-GMCRQSFTGHISDINAVSFFPSG 238
             GH  ++  +   P  +  V+ + D + +LWD RD  +    F GH   + + + F SG
Sbjct: 7   LNGHDQELSDVHAHPTQRLVVTSSKDMTFRLWDFRDSALLVNVFQGHTQPVTS-AVFASG 183

Query: 239 YAFATGSDDATCRLFDLR 256
               +GSDD T R++D+R
Sbjct: 184 DKVVSGSDDRTVRVWDMR 237

 Score = 35.8 bits (81), Expect = 0.023,   Method: Compositional matrix adjust.
 Identities = 21/60 (35%), Positives = 33/60 (55%), Gaps = 1/60 (1%)
 Frame = +1

Query: 157 IITSSGDTTCALWDI-ETGQQTTTFTGHSGDVMSLSLSPDLKTFVSGACDASSKLWDIRD 215
           ++TSS D T  LWD  ++      F GH+  V S   +   K  VSG+ D + ++WD+R+
Sbjct: 64  VVTSSKDMTFRLWDFRDSALLVNVFQGHTQPVTSAVFASGDKV-VSGSDDRTVRVWDMRN 240

 Score = 31.2 bits (69), Expect = 0.61,   Method: Compositional matrix adjust.
 Identities = 18/77 (23%), Positives = 37/77 (48%)
 Frame = +1

Query: 51  LRGHLAKIYAMHWGYDSRLLVSASQDGKLIIWDSYTTNKMHAIPLRSSWVMTCAYAPSGN 110
           L GH  ++  +H     RL+V++S+D    +WD   +  +  +    +  +T A   SG+
Sbjct: 7   LNGHDQELSDVHAHPTQRLVVTSSKDMTFRLWDFRDSALLVNVFQGHTQPVTSAVFASGD 186

Query: 111 YVACGGLDNICSIYNLK 127
            V  G  D    +++++
Sbjct: 187 KVVSGSDDRTVRVWDMR 237
>11493
          Length = 535

 Score = 47.0 bits (110), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 28/110 (25%), Positives = 50/110 (45%), Gaps = 3/110 (2%)
 Frame = -2

Query: 145 YLSCCRFLDDGQIITSSGD-TTCALWDI--ETGQQTTTFTGHSGDVMSLSLSPDLKTFVS 201
           Y+   + L DG+ +   G+ +  ++WD+   T +     T  +    +L++SPD K   S
Sbjct: 333 YIRSVKLLPDGRTLIVGGEASNLSIWDLASPTPRIKAELTSAAPACYALAISPDSKVCFS 154

Query: 202 GACDASSKLWDIRDGMCRQSFTGHISDINAVSFFPSGYAFATGSDDATCR 251
              D +  +WD+ + +  + F GH    + +   P G    TG  D T R
Sbjct: 153 CCSDGNIAVWDLHNEILVRQFQGHTDGASCIDISPDGSRLWTGGLDNTVR 4

 Score = 40.0 bits (92), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 35/168 (20%), Positives = 69/168 (41%), Gaps = 5/168 (2%)
 Frame = -2

Query: 175 QQTTTFTGHSGDVMSLSLSPDLKTFVSGACDASSKLWDI-----RDGMCRQSFTGHISDI 229
           +Q  T + H   V ++++S   K   +G      K+WDI     ++ + +       + I
Sbjct: 501 RQINTLS-HGEVVCAVTISNPTKYVYTGG-KGCVKVWDISQPGNKNPVSQLDCLQRDNYI 328

Query: 230 NAVSFFPSGYAFATGSDDATCRLFDLRADQELLLYSHDNIICGITSVAFSKSGRLLLAGY 289
            +V   P G     G + +   ++DL +    +     +      ++A S   ++  +  
Sbjct: 327 RSVKLLPDGRTLIVGGEASNLSIWDLASPTPRIKAELTSAAPACYALAISPDSKVCFSCC 148

Query: 290 DDFNCSVWDALKGGRSGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLR 337
            D N +VWD           GH +  SC+ ++ DG  + TG  D+ +R
Sbjct: 147 SDGNIAVWDLHNEILVRQFQGHTDGASCIDISPDGSRLWTGGLDNTVR 4

 Score = 29.6 bits (65), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 18/74 (24%), Positives = 30/74 (40%)
 Frame = -2

Query: 46  RTRRTLRGHLAKIYAMHWGYDSRLLVSASQDGKLIIWDSYTTNKMHAIPLRSSWVMTCAY 105
           R +  L       YA+    DS++  S   DG + +WD +    +      +        
Sbjct: 234 RIKAELTSAAPACYALAISPDSKVCFSCCSDGNIAVWDLHNEILVRQFQGHTDGASCIDI 55

Query: 106 APSGNYVACGGLDN 119
           +P G+ +  GGLDN
Sbjct: 54  SPDGSRLWTGGLDN 13
>01598
          Length = 1545

 Score = 45.8 bits (107), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 33/125 (26%), Positives = 60/125 (48%), Gaps = 15/125 (12%)
 Frame = +1

Query: 104  AYAPSGNYVACGGLDNICSIYNLKT----REGNVRVS------RELPGHTGYLSCCRFLD 153
            A +P  +++A  G D +  + +L +    REG+   S      REL GH+  ++   +  
Sbjct: 1153 AGSPCCHWLAAAGNDQVIHVVDLASVFAEREGDKETSLILTSLRELSGHSQRVTDMSWSP 1332

Query: 154  --DGQIITSSGDTTCALWDIETGQQTTTFTGHSGDVMSLSLS---PDLKTFVSGACDASS 208
              D ++++   D    +WD++ G     F GH G +++   S   PDL   ++G  DAS 
Sbjct: 1333 HHDARLVSVGYDAEAFVWDVQKGTALAQFKGHMGRLLTCQFSGLDPDL--VMTGGSDASV 1506

Query: 209  KLWDI 213
             +W +
Sbjct: 1507 HVWRV 1521

 Score = 34.3 bits (77), Expect = 0.072,   Method: Compositional matrix adjust.
 Identities = 47/204 (23%), Positives = 75/204 (36%), Gaps = 8/204 (3%)
 Frame = +1

Query: 60  AMHW-GYDSRLLVSASQDGKLIIWD-SYTTNKMHAIPLRSSWVMTCAYAPSGNYVACGGL 117
           A+HW   +   LVS+S  G L++W   YT  + +          T  Y P    V     
Sbjct: 241 AIHWLKSNPEQLVSSSSGGDLLLWSLRYTKGQAYQT------FQTSDYRPHMRPVF---- 390

Query: 118 DNICSIYNLKTREGNVRVSRELPGHTGYLSCCRFLDDGQIITSSGDTTCALWDIETGQQT 177
            NIC+                        + C F  D Q++         LWD+ET +  
Sbjct: 391 -NICA------------------SGPDSKTLCTFAQDRQVV---------LWDLETMEAV 486

Query: 178 TTFTGHSGDVMSLSLSP-DLKTFVSGACDASSKLWDIRDGMCRQSFT----GHISDINAV 232
            +     G V  +  SP D      G  D+  + W++ +       T    G  S + AV
Sbjct: 487 ASMATLGGHVYCVRTSPIDPGRVAVGVGDSMIRTWNMSNKTNPYDVTTLWQGIKSKVTAV 666

Query: 233 SFFPSGYAF-ATGSDDATCRLFDL 255
           ++ P+   +   G+DD    +FD+
Sbjct: 667 AWHPTKEGWLGFGTDDGRIGVFDV 738

 Score = 32.7 bits (73), Expect = 0.22,   Method: Compositional matrix adjust.
 Identities = 18/56 (32%), Positives = 26/56 (46%), Gaps = 1/56 (1%)
 Frame = +1

Query: 180  FTGHSGDVMSLSLSPDLKT-FVSGACDASSKLWDIRDGMCRQSFTGHISDINAVSF 234
             +GHS  V  +S SP      VS   DA + +WD++ G     F GH+  +    F
Sbjct: 1288 LSGHSQRVTDMSWSPHHDARLVSVGYDAEAFVWDVQKGTALAQFKGHMGRLLTCQF 1455

 Score = 28.5 bits (62), Expect = 4.4,   Method: Compositional matrix adjust.
 Identities = 51/218 (23%), Positives = 78/218 (35%), Gaps = 27/218 (12%)
 Frame = +1

Query: 149  CRFLDDGQIITSSGDTTCALWDIETGQQTTTFTGHSG-DVMSLSLSPDLKTFVSGACDAS 207
            C+ L+    + S G+      DI             G     LS SPD      G  + S
Sbjct: 865  CKILEHSSAVLSRGEKKANAIDITQKIGAVNSDQVKGLKATELSWSPDQNAAAVGTDEGS 1044

Query: 208  SKLWDIRDGMCRQSFTGHISDINAVSFFP-------SG----YAFATGSDDATCRLFDL- 255
              +  I+D     +       IN V + P       +G    +  A   +D    + DL 
Sbjct: 1045 VYVVTIQDLKIVAAIRTQQKLINCVRWHPRLTDQSPAGSPCCHWLAAAGNDQVIHVVDLA 1224

Query: 256  ------RADQEL-LLYSHDNIICG----ITSVAFSK--SGRLLLAGYDDFNCSVWDALKG 302
                    D+E  L+ +    + G    +T +++S     RL+  GYD     VWD  KG
Sbjct: 1225 SVFAEREGDKETSLILTSLRELSGHSQRVTDMSWSPHHDARLVSVGYD-AEAFVWDVQKG 1401

Query: 303  GRSGVLAGHDNR-VSCLGVTDDGMAVATGSWDSFLRIW 339
                   GH  R ++C     D   V TG  D+ + +W
Sbjct: 1402 TALAQFKGHMGRLLTCQFSGLDPDLVMTGGSDASVHVW 1515
>01249
          Length = 1743

 Score = 45.4 bits (106), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 35/113 (30%), Positives = 55/113 (48%), Gaps = 14/113 (12%)
 Frame = -1

Query: 242  ATGSDDATCRLFDLRADQELLLYSHDNIICGITSVAFSKSGRLLLAGYD--DFNCS---- 295
            A+ S D TC+L+D+ +   L    ++    G+  +   K    LLAG D  D  CS    
Sbjct: 1158 ASSSSDGTCKLWDMLSGALLRTMVYET---GVGCLIMDKQEHFLLAGLDNGDILCSPLFG 988

Query: 296  ------VWDALKGGRSG--VLAGHDNRVSCLGVTDDGMAVATGSWDSFLRIWN 340
                  V+ +    ++G  VL GH + V+CL  + DG  +A+GS +  + IWN
Sbjct: 987  QISQSEVFVSKHTTKAGERVLQGHSDAVTCLAFSSDGQRLASGSQNGKVIIWN 829

 Score = 33.9 bits (76), Expect = 0.11,   Method: Compositional matrix adjust.
 Identities = 14/36 (38%), Positives = 22/36 (61%)
 Frame = -1

Query: 48  RRTLRGHLAKIYAMHWGYDSRLLVSASQDGKLIIWD 83
            R L+GH   +  + +  D + L S SQ+GK+IIW+
Sbjct: 936 ERVLQGHSDAVTCLAFSSDGQRLASGSQNGKVIIWN 829

 Score = 29.3 bits (64), Expect = 2.2,   Method: Compositional matrix adjust.
 Identities = 42/179 (23%), Positives = 68/179 (37%), Gaps = 28/179 (15%)
 Frame = -1

Query: 66   DSRLLVSASQDGKLIIWD---SYTTNKMHAIPLRSSWVMTCAYAP-SGNYVACGGL---- 117
            D    V A+  G L IWD     TT    A  L+    +     P +G +V CGG     
Sbjct: 1338 DGSQFVVATSSGHLNIWDFARVVTTTSQRARGLKPGRTINAHSEPITGLHVGCGGPAARV 1159

Query: 118  -----DNICSIYNLKTREGNVRVSRELPGHTGYLSCCRF----------LDDGQIITSSG 162
                 D  C ++++ +      + R +   TG + C             LD+G I+ S  
Sbjct: 1158 ASSSSDGTCKLWDMLSGA----LLRTMVYETG-VGCLIMDKQEHFLLAGLDNGDILCSPL 994

Query: 163  DTTCALWDIETGQQTT-----TFTGHSGDVMSLSLSPDLKTFVSGACDASSKLWDIRDG 216
                +  ++   + TT        GHS  V  L+ S D +   SG+ +    +W++  G
Sbjct: 993  FGQISQSEVFVSKHTTKAGERVLQGHSDAVTCLAFSSDGQRLASGSQNGKVIIWNMESG 817

 Score = 27.7 bits (60), Expect = 6.2,   Method: Compositional matrix adjust.
 Identities = 39/180 (21%), Positives = 70/180 (38%), Gaps = 27/180 (15%)
 Frame = -1

Query: 150  RFLDDG-QIITSSGDTTCALWDIETGQQTT-----------TFTGHSGDVMSLSLS---P 194
            +F DDG Q + ++      +WD      TT           T   HS  +  L +    P
Sbjct: 1350 QFTDDGSQFVVATSSGHLNIWDFARVVTTTSQRARGLKPGRTINAHSEPITGLHVGCGGP 1171

Query: 195  DLKTFVSGACDASSKLWDIRDGMCRQSFTGHISDINAVSFFPSGYAFATGSD--DATC-R 251
              +   S + D + KLWD+  G   ++   + + +  +      +    G D  D  C  
Sbjct: 1170 AARV-ASSSSDGTCKLWDMLSGALLRTMV-YETGVGCLIMDKQEHFLLAGLDNGDILCSP 997

Query: 252  LFDLRADQELLLYSH-----DNIICG----ITSVAFSKSGRLLLAGYDDFNCSVWDALKG 302
            LF   +  E+ +  H     + ++ G    +T +AFS  G+ L +G  +    +W+   G
Sbjct: 996  LFGQISQSEVFVSKHTTKAGERVLQGHSDAVTCLAFSSDGQRLASGSQNGKVIIWNMESG 817
>14500
          Length = 1238

 Score = 35.0 bits (79), Expect(2) = 5e-05,   Method: Compositional matrix adjust.
 Identities = 26/107 (24%), Positives = 43/107 (40%), Gaps = 2/107 (1%)
 Frame = +3

Query: 236 PSGYAFATGSDDATCRLFDLRADQELLLYSHDNIICGITSVAFSKSGRLLLA--GYDDFN 293
           PS  A   G+ D     ++      L      + +C +    +SK  R L++  G+    
Sbjct: 240 PSLLASGGGTADRHIHFWNCNTGTNLSSVDTKSQVCALL---WSKEHRELISSHGFAQNQ 410

Query: 294 CSVWDALKGGRSGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLRIWN 340
             +W      R   L GH  RV  + ++ DG  V + + D  LR+W 
Sbjct: 411 LIIWKYPAMSRVAELTGHTARVLHMAMSPDGETVVSAAADETLRLWK 551

 Score = 28.9 bits (63), Expect(2) = 5e-05,   Method: Compositional matrix adjust.
 Identities = 20/60 (33%), Positives = 30/60 (50%), Gaps = 5/60 (8%)
 Frame = +2

Query: 179 TFTGHSGDVMSLSLSPDLKTFVSGACDASSKLW--DIRDGMCRQ---SFTGHISDINAVS 233
           T +GHS +V  L  SPD K   SGA D    +W   +  G   Q   +F+ H + + A++
Sbjct: 44  TLSGHSQEVCGLRWSPDGKYLASGANDNLLCVWPAQVTGGNSTQPLHTFSQHQAAVKALA 223

 Score = 39.3 bits (90), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 18/62 (29%), Positives = 32/62 (51%), Gaps = 2/62 (3%)
 Frame = +3

Query: 153 DDGQIITSSG--DTTCALWDIETGQQTTTFTGHSGDVMSLSLSPDLKTFVSGACDASSKL 210
           +  ++I+S G       +W      +    TGH+  V+ +++SPD +T VS A D + +L
Sbjct: 366 EHRELISSHGFAQNQLIIWKYPAMSRVAELTGHTARVLHMAMSPDGETVVSAAADETLRL 545

Query: 211 WD 212
           W 
Sbjct: 546 WK 551

 Score = 33.1 bits (74), Expect = 0.19,   Method: Compositional matrix adjust.
 Identities = 16/57 (28%), Positives = 25/57 (43%)
 Frame = +2

Query: 41 GRIQMRTRRTLRGHLAKIYAMHWGYDSRLLVSASQDGKLIIWDSYTTNKMHAIPLRS 97
          GR+      TL GH  ++  + W  D + L S + D  L +W +  T      PL +
Sbjct: 17 GRVADHHVGTLSGHSQEVCGLRWSPDGKYLASGANDNLLCVWPAQVTGGNSTQPLHT 187

 Score = 25.0 bits (53), Expect(2) = 0.59,   Method: Compositional matrix adjust.
 Identities = 23/103 (22%), Positives = 41/103 (39%), Gaps = 3/103 (2%)
 Frame = +3

Query: 161 SGDTTCALWDIETGQQTTTFTGHSGDVMSLSLSPDLKTFVSGACDASSKL--WDIRDGMC 218
           + D     W+  TG   ++    S  V +L  S + +  +S    A ++L  W       
Sbjct: 267 TADRHIHFWNCNTGTNLSSVDTKS-QVCALLWSKEHRELISSHGFAQNQLIIWKYPAMSR 443

Query: 219 RQSFTGHISDINAVSFFPSGYAFATGSDDATCRLFD-LRADQE 260
               TGH + +  ++  P G    + + D T RL+     D+E
Sbjct: 444 VAELTGHTARVLHMAMSPDGETVVSAAADETLRLWKCFTVDKE 572

 Score = 24.6 bits (52), Expect(2) = 0.59,   Method: Compositional matrix adjust.
 Identities = 9/28 (32%), Positives = 16/28 (57%)
 Frame = +2

Query: 105 YAPSGNYVACGGLDNICSIYNLKTREGN 132
           ++P G Y+A G  DN+  ++  +   GN
Sbjct: 83  WSPDGKYLASGANDNLLCVWPAQVTGGN 166

 Score = 30.4 bits (67), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 15/44 (34%), Positives = 22/44 (50%)
 Frame = +3

Query: 51  LRGHLAKIYAMHWGYDSRLLVSASQDGKLIIWDSYTTNKMHAIP 94
           L GH A++  M    D   +VSA+ D  L +W  +T +K    P
Sbjct: 453 LTGHTARVLHMAMSPDGETVVSAAADETLRLWKCFTVDKEKKRP 584
>10264
          Length = 416

 Score = 42.7 bits (99), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 32/132 (24%), Positives = 60/132 (45%), Gaps = 20/132 (15%)
 Frame = -1

Query: 102 TCAYAPSGNYVACGGLDNICSIYNLKT---------REGNVRVS------RELPGHTGYL 146
           + A +P  +++A  G D +  + +L +         REG+          REL GH+  +
Sbjct: 413 SPAGSPRCHWLAAAGNDQVIHVVDLASVFGEMGATEREGDKETLLILTSLRELSGHSQRV 234

Query: 147 SCCRFLD--DGQIITSSGDTTCALWDIETGQQTTTFTGHSGDVMSLSLS---PDLKTFVS 201
           +   +    D ++++   D    +WD++ G     F GH G +++   S   PDL   ++
Sbjct: 233 TDMSWSPHHDARLVSVGYDAEAFVWDVQKGTALAQFKGHMGRLLTCQFSGLDPDL--VMT 60

Query: 202 GACDASSKLWDI 213
           G  DAS  +W +
Sbjct: 59  GGSDASVHVWRV 24

 Score = 32.3 bits (72), Expect = 0.25,   Method: Compositional matrix adjust.
 Identities = 18/56 (32%), Positives = 26/56 (46%), Gaps = 1/56 (1%)
 Frame = -1

Query: 180 FTGHSGDVMSLSLSPDLKT-FVSGACDASSKLWDIRDGMCRQSFTGHISDINAVSF 234
            +GHS  V  +S SP      VS   DA + +WD++ G     F GH+  +    F
Sbjct: 257 LSGHSQRVTDMSWSPHHDARLVSVGYDAEAFVWDVQKGTALAQFKGHMGRLLTCQF 90
>19863
          Length = 502

 Score = 42.7 bits (99), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 21/64 (32%), Positives = 36/64 (56%), Gaps = 1/64 (1%)
 Frame = +1

Query: 153 DDG-QIITSSGDTTCALWDIETGQQTTTFTGHSGDVMSLSLSPDLKTFVSGACDASSKLW 211
           DDG Q+++ S D +  +WD+E G Q     GH+G V  +  S D    +S + D + ++W
Sbjct: 1   DDGLQLVSGSSDMSIVVWDVENGVQKLRLQGHAGWVNDVHFSQDQCWLLSCSNDNTVRIW 180

Query: 212 DIRD 215
           +I +
Sbjct: 181 NIEE 192

 Score = 39.3 bits (90), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 21/85 (24%), Positives = 39/85 (45%)
 Frame = +1

Query: 199 FVSGACDASSKLWDIRDGMCRQSFTGHISDINAVSFFPSGYAFATGSDDATCRLFDLRAD 258
            VSG+ D S  +WD+ +G+ +    GH   +N V F        + S+D T R++++   
Sbjct: 16  LVSGSSDMSIVVWDVENGVQKLRLQGHAGWVNDVHFSQDQCWLLSCSNDNTVRIWNIEES 195

Query: 259 QELLLYSHDNIICGITSVAFSKSGR 283
            ++ +        G+     SK G+
Sbjct: 196 DQIPIVMEHKRAQGLKVTKCSKCGK 270

 Score = 31.2 bits (69), Expect = 0.59,   Method: Compositional matrix adjust.
 Identities = 19/59 (32%), Positives = 30/59 (50%)
 Frame = +1

Query: 282 GRLLLAGYDDFNCSVWDALKGGRSGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLRIWN 340
           G  L++G  D +  VWD   G +   L GH   V+ +  + D   + + S D+ +RIWN
Sbjct: 7   GLQLVSGSSDMSIVVWDVENGVQKLRLQGHAGWVNDVHFSQDQCWLLSCSNDNTVRIWN 183
>15780
          Length = 735

 Score = 41.2 bits (95), Expect = 6e-04,   Method: Compositional matrix adjust.
 Identities = 22/62 (35%), Positives = 29/62 (46%)
 Frame = -1

Query: 159 TSSGDTTCALWDIETGQQTTTFTGHSGDVMSLSLSPDLKTFVSGACDASSKLWDIRDGMC 218
           T+  D T  +WDI +G      T H+  V +L  S D     SG  D S +LWD+   M 
Sbjct: 723 TAGADHTVIVWDIASGTAVAHLTAHTDTVYALCFSRDGTVLASGGMDNSIRLWDLARVME 544

Query: 219 RQ 220
            Q
Sbjct: 543 EQ 538

 Score = 35.4 bits (80), Expect = 0.034,   Method: Compositional matrix adjust.
 Identities = 32/115 (27%), Positives = 50/115 (43%), Gaps = 1/115 (0%)
 Frame = -1

Query: 197 KTFVSGACDASSKLWDIRDGMCRQSFTGHISDINAVSFFPSGYAFATGSDDATCRLFDL- 255
           K   +   D +  +WDI  G      T H   + A+ F   G   A+G  D + RL+DL 
Sbjct: 735 KYLSTAGADHTVIVWDIASGTAVAHLTAHTDTVYALCFSRDGTVLASGGMDNSIRLWDLA 556

Query: 256 RADQELLLYSHDNIICGITSVAFSKSGRLLLAGYDDFNCSVWDALKGGRSGVLAG 310
           R  +E    +  N+    +S++ + +  LLL  Y   +  V+  L   R  VL G
Sbjct: 555 RVMEEQDPETDSNV---PSSLSVNTNPALLLGTYYTKSSPVF-GLHFTRRNVLLG 403

 Score = 27.7 bits (60), Expect = 7.9,   Method: Compositional matrix adjust.
 Identities = 14/59 (23%), Positives = 29/59 (49%)
 Frame = -1

Query: 68  RLLVSASQDGKLIIWDSYTTNKMHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNL 126
           + L +A  D  +I+WD  +   +  +   +  V    ++  G  +A GG+DN   +++L
Sbjct: 735 KYLSTAGADHTVIVWDIASGTAVAHLTAHTDTVYALCFSRDGTVLASGGMDNSIRLWDL 559
>01462
          Length = 995

 Score = 40.8 bits (94), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 18/59 (30%), Positives = 30/59 (50%)
 Frame = +2

Query: 156 QIITSSGDTTCALWDIETGQQTTTFTGHSGDVMSLSLSPDLKTFVSGACDASSKLWDIR 214
           ++   +GD    +WDIE GQ      GH   +  + +  D +  VS + D + ++WDIR
Sbjct: 239 RLYAGAGDRKIHVWDIEAGQYLNAMEGHKDYIHKVVMKNDAQECVSASEDGTVRMWDIR 415

 Score = 37.4 bits (85), Expect = 0.010,   Method: Compositional matrix adjust.
 Identities = 24/89 (26%), Positives = 43/89 (48%), Gaps = 11/89 (12%)
 Frame = +2

Query: 51  LRGHLAKIYAMHWGYDSRLLVSASQDGKLIIWD-----------SYTTNKMHAIPLRSSW 99
           + GH   I+ +    D++  VSAS+DG + +WD             + N++ + PL   W
Sbjct: 311 MEGHKDYIHKVVMKNDAQECVSASEDGTVRMWDIRSSTETVHCLEPSKNELCSRPLLGKW 490

Query: 100 VMTCAYAPSGNYVACGGLDNICSIYNLKT 128
           +   A  P   ++ CGG   + S ++L+T
Sbjct: 491 LRCLALDPEEGWLVCGGGPKL-SAWHLRT 574

 Score = 36.2 bits (82), Expect = 0.021,   Method: Compositional matrix adjust.
 Identities = 21/77 (27%), Positives = 34/77 (44%), Gaps = 2/77 (2%)
 Frame = +2

Query: 197 KTFVSGACDASSKLWDIRDGMCRQSFTGHISDINAVSFFPSGYAFATGSDDATCRLFDLR 256
           +   +GA D    +WDI  G    +  GH   I+ V          + S+D T R++D+R
Sbjct: 236 RRLYAGAGDRKIHVWDIEAGQYLNAMEGHKDYIHKVVMKNDAQECVSASEDGTVRMWDIR 415

Query: 257 ADQELL--LYSHDNIIC 271
           +  E +  L    N +C
Sbjct: 416 SSTETVHCLEPSKNELC 466

 Score = 31.6 bits (70), Expect = 0.43,   Method: Compositional matrix adjust.
 Identities = 16/58 (27%), Positives = 26/58 (44%)
 Frame = +2

Query: 283 RLLLAGYDDFNCSVWDALKGGRSGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLRIWN 340
           R L AG  D    VWD   G     + GH + +  + + +D     + S D  +R+W+
Sbjct: 236 RRLYAGAGDRKIHVWDIEAGQYLNAMEGHKDYIHKVVMKNDAQECVSASEDGTVRMWD 409
>18981
          Length = 407

 Score = 40.8 bits (94), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 34/111 (30%), Positives = 51/111 (45%)
 Frame = -2

Query: 152 LDDGQIITSSGDTTCALWDIETGQQTTTFTGHSGDVMSLSLSPDLKTFVSGACDASSKLW 211
           L D  II+++ D T  +W ++      T  GH+ DV  + +    +  VSG+ D +  +W
Sbjct: 394 LLDNMIISAATDRTLRVWCLKNTCLLHTLRGHNDDVECVCIYG--RRVVSGSWDKTLIVW 221

Query: 212 DIRDGMCRQSFTGHISDINAVSFFPSGYAFATGSDDATCRLFDLRADQELL 262
           ++  G       GH   I AV  F  G A + GS D   R + L   Q LL
Sbjct: 220 EVDTGRPVHQLHGHTEAITAVQ-FDEGKAVS-GSADGDVRTWALDTGQCLL 74

 Score = 36.6 bits (83), Expect = 0.016,   Method: Compositional matrix adjust.
 Identities = 27/115 (23%), Positives = 50/115 (43%), Gaps = 1/115 (0%)
 Frame = -2

Query: 110 NYVACGGLDNICSIYNLKTREGNVRVSRELPGHTGYLSC-CRFLDDGQIITSSGDTTCAL 168
           N +     D    ++ LK    N  +   L GH   + C C +    ++++ S D T  +
Sbjct: 385 NMIISAATDRTLRVWCLK----NTCLLHTLRGHNDDVECVCIY--GRRVVSGSWDKTLIV 224

Query: 169 WDIETGQQTTTFTGHSGDVMSLSLSPDLKTFVSGACDASSKLWDIRDGMCRQSFT 223
           W+++TG+      GH+  + ++    D    VSG+ D   + W +  G C  + T
Sbjct: 223 WEVDTGRPVHQLHGHTEAITAVQF--DEGKAVSGSADGDVRTWALDTGQCLLTMT 65

 Score = 28.1 bits (61), Expect = 5.3,   Method: Compositional matrix adjust.
 Identities = 16/57 (28%), Positives = 26/57 (45%)
 Frame = -2

Query: 284 LLLAGYDDFNCSVWDALKGGRSGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLRIWN 340
           ++++   D    VW          L GH++ V C+ +   G  V +GSWD  L +W 
Sbjct: 382 MIISAATDRTLRVWCLKNTCLLHTLRGHNDDVECVCIY--GRRVVSGSWDKTLIVWE 218
>15118
          Length = 1074

 Score = 40.4 bits (93), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 32/135 (23%), Positives = 58/135 (42%), Gaps = 4/135 (2%)
 Frame = +3

Query: 210 LWDIRDGMCRQSF---TGHISDINAVSFFPSGYAFATGSDDATCRLFDLRA-DQELLLYS 265
           +++++ G  R SF     H+S +  V+F        T   D   + +   + D+  +L  
Sbjct: 135 IYNLQSGKHRGSFGDTVAHVSGVRGVAFDAFNCLLITAGGDCDIKFWRFGSRDRARVLLK 314

Query: 266 HDNIICGITSVAFSKSGRLLLAGYDDFNCSVWDALKGGRSGVLAGHDNRVSCLGVTDDGM 325
              +  GI+ +   +   +L    +DF  SV D        V +GH N ++ L  + DG 
Sbjct: 315 ELKMSEGISRILLHRDSNMLAVVLEDFTVSVIDVDTLRVVRVFSGHSNSITDLSFSGDGR 494

Query: 326 AVATGSWDSFLRIWN 340
            + T S D  +R W+
Sbjct: 495 WLITASMDCTVRTWS 539

 Score = 33.9 bits (76), Expect = 0.096,   Method: Compositional matrix adjust.
 Identities = 24/107 (22%), Positives = 45/107 (42%)
 Frame = +3

Query: 137 RELPGHTGYLSCCRFLDDGQIITSSGDTTCALWDIETGQQTTTFTGHSGDVMSLSLSPDL 196
           +EL    G        D   +     D T ++ D++T +    F+GHS  +  LS S D 
Sbjct: 312 KELKMSEGISRILLHRDSNMLAVVLEDFTVSVIDVDTLRVVRVFSGHSNSITDLSFSGDG 491

Query: 197 KTFVSGACDASSKLWDIRDGMCRQSFTGHISDINAVSFFPSGYAFAT 243
           +  ++ + D + + W +  G     F    + + +++  PS    AT
Sbjct: 492 RWLITASMDCTVRTWSLVHGRLIDCFAVEAA-VTSLTMSPSQDFLAT 629

 Score = 28.9 bits (63), Expect = 3.3,   Method: Compositional matrix adjust.
 Identities = 36/168 (21%), Positives = 58/168 (34%), Gaps = 3/168 (1%)
 Frame = +3

Query: 91  HAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELPGHTGYLSCCR 150
           H    R +       +  GNYVA G       IYNL++ +        +   +G      
Sbjct: 39  HGAQHRFTTAQAVDISSCGNYVAVGYSSGHLDIYNLQSGKHRGSFGDTVAHVSGVRGVAF 218

Query: 151 FLDDGQIITSSGDTTCALWDIETGQQTTTFTGH---SGDVMSLSLSPDLKTFVSGACDAS 207
              +  +IT+ GD     W   +  +          S  +  + L  D         D +
Sbjct: 219 DAFNCLLITAGGDCDIKFWRFGSRDRARVLLKELKMSEGISRILLHRDSNMLAVVLEDFT 398

Query: 208 SKLWDIRDGMCRQSFTGHISDINAVSFFPSGYAFATGSDDATCRLFDL 255
             + D+      + F+GH + I  +SF   G    T S D T R + L
Sbjct: 399 VSVIDVDTLRVVRVFSGHSNSITDLSFSGDGRWLITASMDCTVRTWSL 542
>31864
          Length = 545

 Score = 40.0 bits (92), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 34/126 (26%), Positives = 56/126 (44%), Gaps = 15/126 (11%)
 Frame = +2

Query: 142 HTGYLSCCRFLDDGQI-ITSSGDTTCALWDIETGQQTTTFTGHSGDVMSLSLSPDLKTFV 200
           HTG ++  +   DG + +T+S DTT  L+D E+     T+      V S ++SP L   V
Sbjct: 47  HTGGINDMQLSKDGTMFVTASKDTTAKLFDSESLMCLKTYKTER-PVNSAAISPILDHVV 223

Query: 201 SG--------------ACDASSKLWDIRDGMCRQSFTGHISDINAVSFFPSGYAFATGSD 246
            G              A    S+ + +          GH   IN+++F P G ++A+G +
Sbjct: 224 LGGGQDAMEVTTTSTKAGKFDSRFFHLIYEEEFARLKGHFGPINSLAFHPDGKSYASGGE 403

Query: 247 DATCRL 252
           D   R+
Sbjct: 404 DGFVRV 421

 Score = 30.4 bits (67), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 28/120 (23%), Positives = 47/120 (39%), Gaps = 10/120 (8%)
 Frame = +2

Query: 54  HLAKIYAMHWGYDSRLLVSASQDGKLIIWDSYTTNKMHAIPLRSSWVMTCAYAPSGNYVA 113
           H   I  M    D  + V+AS+D    ++DS +   +         V + A +P  ++V 
Sbjct: 47  HTGGINDMQLSKDGTMFVTASKDTTAKLFDSESLMCLKTYKTERP-VNSAAISPILDHVV 223

Query: 114 CGGLDNICSIYNLKTREGNVR------VSRE----LPGHTGYLSCCRFLDDGQIITSSGD 163
            GG  +   +    T+ G         +  E    L GH G ++   F  DG+   S G+
Sbjct: 224 LGGGQDAMEVTTTSTKAGKFDSRFFHLIYEEEFARLKGHFGPINSLAFHPDGKSYASGGE 403
>16199
          Length = 694

 Score = 33.1 bits (74), Expect(2) = 0.001,   Method: Compositional matrix adjust.
 Identities = 13/44 (29%), Positives = 23/44 (52%)
 Frame = +2

Query: 191 SLSPDLKTFVSGACDASSKLWDIRDGMCRQSFTGHISDINAVSF 234
              PD   F +G  D+  K+WD+++     +F GH   + ++SF
Sbjct: 92  QFHPDGLIFATGTEDSVIKIWDLKERANVANFQGHQGPVTSISF 223

 Score = 26.2 bits (56), Expect(2) = 0.001,   Method: Compositional matrix adjust.
 Identities = 19/71 (26%), Positives = 33/71 (46%), Gaps = 7/71 (9%)
 Frame = +1

Query: 237 SGYAFATGSDDATCRLFDLRADQELLLYSHDNIICG----ITSVAFSKSGRLLLAGYDD- 291
           +GY  AT ++D+  +L+DLR      L +   +  G    + ++ F +SG  L     D 
Sbjct: 229 NGYYLATSAEDSVVKLWDLRK-----LKNFKTLQLGDKYEVKALCFDQSGTYLAVAGSDV 393

Query: 292 --FNCSVWDAL 300
             + C  W+ L
Sbjct: 394 RVYLCKQWNEL 426

 Score = 38.1 bits (87), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 18/49 (36%), Positives = 26/49 (53%), Gaps = 1/49 (2%)
 Frame = +2

Query: 146 LSCCRFLDDGQII-TSSGDTTCALWDIETGQQTTTFTGHSGDVMSLSLS 193
           L+C +F  DG I  T + D+   +WD++       F GH G V S+S S
Sbjct: 80  LTCAQFHPDGLIFATGTEDSVIKIWDLKERANVANFQGHQGPVTSISFS 226

 Score = 30.8 bits (68), Expect = 0.92,   Method: Compositional matrix adjust.
 Identities = 14/56 (25%), Positives = 30/56 (53%)
 Frame = +2

Query: 226 ISDINAVSFFPSGYAFATGSDDATCRLFDLRADQELLLYSHDNIICGITSVAFSKS 281
           +  +    F P G  FATG++D+  +++DL+    +  +        +TS++FS++
Sbjct: 71  VPALTCAQFHPDGLIFATGTEDSVIKIWDLKERANVANFQGHQ--GPVTSISFSET 232
>00825
          Length = 1821

 Score = 40.0 bits (92), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 30/123 (24%), Positives = 53/123 (43%), Gaps = 2/123 (1%)
 Frame = -2

Query: 189  SLSLSP-DLKTFVSGACDASSKLWDIRD-GMCRQSFTGHISDINAVSFFPSGYAFATGSD 246
            +LS +P +  T  S   D +   +D+R   M       H + +  V + P+G  F +   
Sbjct: 1346 ALSWNPMEAFTITSANEDGNLYTFDMRKLSMPLNMHRDHTAAVMDVDYCPTGREFVSAGY 1167

Query: 247  DATCRLFDLRADQELLLYSHDNIICGITSVAFSKSGRLLLAGYDDFNCSVWDALKGGRSG 306
            D   R+F +       +Y H   +  + SV +S+  + + +  D+ N  VW A+     G
Sbjct: 1166 DKVIRIFPVDKGHSREVY-HTKRMQRVGSVVWSRDSKYIFSASDEMNIRVWKAVAWEALG 990

Query: 307  VLA 309
             LA
Sbjct: 989  KLA 981
>31384
          Length = 474

 Score = 38.5 bits (88), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 22/81 (27%), Positives = 39/81 (48%), Gaps = 6/81 (7%)
 Frame = -1

Query: 146 LSCCRF----LDDGQIITSSGDTTCALWDIETGQQTTTFTG--HSGDVMSLSLSPDLKTF 199
           +SC +F    L    +I+ S D   + W+++   QT       H+G V+ +  S D    
Sbjct: 267 VSCLKFSPGALPSTFLISGSWDNKVSCWEVQQSGQTIPKAQQTHTGPVLDVDWSDDGTKV 88

Query: 200 VSGACDASSKLWDIRDGMCRQ 220
            + +CD ++K+WD+    C Q
Sbjct: 87  FTASCDKTAKVWDLNSNQCMQ 25

 Score = 27.7 bits (60), Expect = 7.9,   Method: Compositional matrix adjust.
 Identities = 23/88 (26%), Positives = 38/88 (43%), Gaps = 5/88 (5%)
 Frame = -1

Query: 258 DQELLLYSHDNIICGITSVAFSK---SGRLLLAGYDDFNCSVWDALKGGRSGVLAGHDNR 314
           D E+     D++ C    + FS        L++G  D   S W+  + G++   A   + 
Sbjct: 300 DFEVTSPPDDSVSC----LKFSPGALPSTFLISGSWDNKVSCWEVQQSGQTIPKAQQTHT 133

Query: 315 VSCLGV--TDDGMAVATGSWDSFLRIWN 340
              L V  +DDG  V T S D   ++W+
Sbjct: 132 GPVLDVDWSDDGTKVFTASCDKTAKVWD 49
>34005
          Length = 456

 Score = 37.0 bits (84), Expect = 0.010,   Method: Compositional matrix adjust.
 Identities = 30/110 (27%), Positives = 49/110 (44%), Gaps = 6/110 (5%)
 Frame = +1

Query: 186 DVMSLSLSPDLKTFVSGACDASSKLWDIRDGM---CRQSFTGHISDINAVSFFP---SGY 239
           +V  LS SPD     SG+ D S  +WD   GM      + T H + + AV++ P      
Sbjct: 118 EVCGLSWSPDATFLASGSNDNSVNIWDSTLGMDVPPLHTLTSHQAAVKAVAWCPWQTRML 297

Query: 240 AFATGSDDATCRLFDLRADQELLLYSHDNIICGITSVAFSKSGRLLLAGY 289
           A   G++D   R ++      +      + +C   SV + K  R L++G+
Sbjct: 298 ATGGGTNDRHIRFWNTNTGACVKAVDTQSQVC---SVLWCKEHRELVSGH 438
>27806
          Length = 419

 Score = 36.2 bits (82), Expect = 0.019,   Method: Compositional matrix adjust.
 Identities = 18/70 (25%), Positives = 32/70 (45%)
 Frame = -1

Query: 194 PDLKTFVSGACDASSKLWDIRDGMCRQSFTGHISDINAVSFFPSGYAFATGSDDATCRLF 253
           P      + + D +++++ I  G C  ++ GH   +NAV F P      T S D T  ++
Sbjct: 395 PGHPIIGTASADHTARIYSIETGACVLTYGGHQGSVNAVRFHPGQDLVLTASGDHTAHVW 216

Query: 254 DLRADQELLL 263
             +  Q  L+
Sbjct: 215 RAQFSQPSLM 186

 Score = 33.9 bits (76), Expect = 0.099,   Method: Compositional matrix adjust.
 Identities = 24/80 (30%), Positives = 36/80 (45%)
 Frame = -1

Query: 132 NVRVSRELPGHTGYLSCCRFLDDGQIITSSGDTTCALWDIETGQQTTTFTGHSGDVMSLS 191
            V VSR  PGH              I T+S D T  ++ IETG    T+ GH G V ++ 
Sbjct: 413 EVSVSR--PGHP------------IIGTASADHTARIYSIETGACVLTYGGHQGSVNAVR 276

Query: 192 LSPDLKTFVSGACDASSKLW 211
             P     ++ + D ++ +W
Sbjct: 275 FHPGQDLVLTASGDHTAHVW 216
>31054
          Length = 392

 Score = 35.4 bits (80), Expect = 0.033,   Method: Compositional matrix adjust.
 Identities = 28/100 (28%), Positives = 45/100 (45%)
 Frame = -2

Query: 169 WDIETGQQTTTFTGHSGDVMSLSLSPDLKTFVSGACDASSKLWDIRDGMCRQSFTGHISD 228
           W    G      +GH+  + +L+++ D    VSGA + +  LWD R G   Q     +  
Sbjct: 334 WKFPDGNFIQNLSGHNAIINTLAVNSD-GVLVSGADNGTMHLWDWRTGYNFQRIHAAVQP 158

Query: 229 INAVSFFPSGYAFATGSDDATCRLFDLRADQELLLYSHDN 268
            +  S   SG+ FA   D +  RL    AD+ + +Y  D+
Sbjct: 157 GSLDS--ESGF-FACTFDQSESRLITAEADKTIKVYREDD 47

 Score = 30.4 bits (67), Expect = 1.0,   Method: Compositional matrix adjust.
 Identities = 19/58 (32%), Positives = 29/58 (50%)
 Frame = -2

Query: 199 FVSGACDASSKLWDIRDGMCRQSFTGHISDINAVSFFPSGYAFATGSDDATCRLFDLR 256
           F  G+ D   K W   DG   Q+ +GH + IN ++    G    +G+D+ T  L+D R
Sbjct: 367 FAXGSPD-XVKQWKFPDGNFIQNLSGHNAIINTLAVNSDG-VLVSGADNGTMHLWDWR 200
>29912
          Length = 510

 Score = 35.4 bits (80), Expect = 0.037,   Method: Compositional matrix adjust.
 Identities = 37/148 (25%), Positives = 63/148 (42%), Gaps = 8/148 (5%)
 Frame = +3

Query: 97  SSWVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELPGHTGYLSCCRFLDDGQ 156
             ++   ++   GNY+A G       ++++ T++  +R         G LS   F     
Sbjct: 9   EEYIGAVSWIKEGNYLALGTSTGEVQVWDV-TQQKKLRTMAGHAARVGSLSWNSF----- 170

Query: 157 IITSSGDTTCALW--DIETG-QQTTTFTGHSGDVMSLSLSPDLKTFVSGACDASSKLW-- 211
            I SSG  +  +   D+        T +GHS +V  L  SPD K   SGA D    +W  
Sbjct: 171 -IVSSGSRSGNIHHHDVRVADHHVGTLSGHSQEVCGLRWSPDGKYLASGANDNLLCVWPA 347

Query: 212 DIRDGMCRQ---SFTGHISDINAVSFFP 236
            +  G   Q   +F+ H + + A+++ P
Sbjct: 348 QVTGGNSTQPLHTFSQHQAAVKALAWCP 431

 Score = 32.3 bits (72), Expect = 0.30,   Method: Compositional matrix adjust.
 Identities = 27/113 (23%), Positives = 54/113 (47%), Gaps = 6/113 (5%)
 Frame = +3

Query: 141 GHTGYLSCCRFLDDGQII---TSSGDTTCALWDIETGQQTTTFTGHSGDVMSLSLSPDLK 197
           G   Y+    ++ +G  +   TS+G+    +WD+   ++  T  GH+  V SLS +    
Sbjct: 3   GPEEYIGAVSWIKEGNYLALGTSTGEVQ--VWDVTQQKKLRTMAGHAARVGSLSWN---- 164

Query: 198 TFV--SGACDASSKLWDIRDG-MCRQSFTGHISDINAVSFFPSGYAFATGSDD 247
           +F+  SG+   +    D+R       + +GH  ++  + + P G   A+G++D
Sbjct: 165 SFIVSSGSRSGNIHHHDVRVADHHVGTLSGHSQEVCGLRWSPDGKYLASGAND 323

 Score = 31.6 bits (70), Expect = 0.49,   Method: Compositional matrix adjust.
 Identities = 20/75 (26%), Positives = 33/75 (44%), Gaps = 6/75 (8%)
 Frame = +3

Query: 50  TLRGHLAKIYAMHWGYDSRLLVSASQDGKLIIWDSY-----TTNKMHAIPLRSSWVMTCA 104
           TL GH  ++  + W  D + L S + D  L +W +      +T  +H      + V   A
Sbjct: 243 TLSGHSQEVCGLRWSPDGKYLASGANDNLLCVWPAQVTGGNSTQPLHTFSQHQAAVKALA 422

Query: 105 YAP-SGNYVACGGLD 118
           + P   + +A GG D
Sbjct: 423 WCPWQPSXLASGGGD 467

 Score = 29.6 bits (65), Expect = 1.9,   Method: Compositional matrix adjust.
 Identities = 19/64 (29%), Positives = 27/64 (42%)
 Frame = +3

Query: 273 ITSVAFSKSGRLLLAGYDDFNCSVWDALKGGRSGVLAGHDNRVSCLGVTDDGMAVATGSW 332
           I +V++ K G  L  G       VWD  +  +   +AGH  RV  L            SW
Sbjct: 18  IGAVSWIKEGNYLALGTSTGEVQVWDVTQQKKLRTMAGHAARVGSL------------SW 161

Query: 333 DSFL 336
           +SF+
Sbjct: 162 NSFI 173
>26939
          Length = 388

 Score = 34.7 bits (78), Expect = 0.052,   Method: Compositional matrix adjust.
 Identities = 19/77 (24%), Positives = 39/77 (50%), Gaps = 3/77 (3%)
 Frame = +2

Query: 197 KTFVSGACDASSKLWDIRDGMCRQSFTGHISDINAVSFFPSGYAFATGSDDATCRLFDLR 256
           K  VS + D + ++WD+R+  C ++   H     ++ F  +     +GS D T ++++ R
Sbjct: 5   KYLVSASDDKTIRVWDLRNKRCMKTLYAHQHFCTSIDFHKAHPYVISGSVDQTVKVWECR 184

Query: 257 ---ADQELLLYSHDNII 270
              +   + L+ + NII
Sbjct: 185 *EHSANNICLFLNLNII 235

 Score = 33.9 bits (76), Expect = 0.11,   Method: Compositional matrix adjust.
 Identities = 20/62 (32%), Positives = 33/62 (53%), Gaps = 1/62 (1%)
 Frame = +2

Query: 238 GYAFATGSDDATCRLFDLRADQEL-LLYSHDNIICGITSVAFSKSGRLLLAGYDDFNCSV 296
           G    + SDD T R++DLR  + +  LY+H +     TS+ F K+   +++G  D    V
Sbjct: 2   GKYLVSASDDKTIRVWDLRNKRCMKTLYAHQHF---CTSIDFHKAHPYVISGSVDQTVKV 172

Query: 297 WD 298
           W+
Sbjct: 173 WE 178

 Score = 33.1 bits (74), Expect = 0.16,   Method: Compositional matrix adjust.
 Identities = 14/58 (24%), Positives = 27/58 (46%)
 Frame = +2

Query: 157 IITSSGDTTCALWDIETGQQTTTFTGHSGDVMSLSLSPDLKTFVSGACDASSKLWDIR 214
           ++++S D T  +WD+   +   T   H     S+         +SG+ D + K+W+ R
Sbjct: 11  LVSASDDKTIRVWDLRNKRCMKTLYAHQHFCTSIDFHKAHPYVISGSVDQTVKVWECR 184
>27270
          Length = 1078

 Score = 34.3 bits (77), Expect = 0.066,   Method: Compositional matrix adjust.
 Identities = 43/168 (25%), Positives = 62/168 (36%), Gaps = 4/168 (2%)
 Frame = +2

Query: 27  DATLVQITSNMDSVGRIQMRTRRTL----RGHLAKIYAMHWGYDSRLLVSASQDGKLIIW 82
           D+ +V + S   SVG   + T        +GH   +  M W  D R L S+S DG +I W
Sbjct: 176 DSAVVAVGSADGSVGLYSVETHTYTHMLNKGHSKAVTDMCWRADGRTLYSSSLDGHVIGW 355

Query: 83  DSYTTNKMHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELPGH 142
           +    N +H I     W  T     SG +    G+  +C                     
Sbjct: 356 N---VNTLHMI---EKWKAT-----SGRH---HGVHCVC--------------------- 430

Query: 143 TGYLSCCRFLDDGQIITSSGDTTCALWDIETGQQTTTFTGHSGDVMSL 190
               S  R L        + D T  +WD+ T      F+GHS +V+ L
Sbjct: 431 --LCSSSRLL--------TADHTIKMWDLTTKNVLQEFSGHSTEVIKL 544

 Score = 28.1 bits (61), Expect = 5.9,   Method: Compositional matrix adjust.
 Identities = 33/152 (21%), Positives = 61/152 (40%), Gaps = 6/152 (3%)
 Frame = +2

Query: 112 VACGGLDNICSIYNLKTREGNVRVSRELPGHTGYLS-CCRFLDDGQIITSSGDTTCALWD 170
           VA G  D    +Y+++T      +++   GH+  ++  C   D   + +SS D     W+
Sbjct: 188 VAVGSADGSVGLYSVETHTYTHMLNK---GHSKAVTDMCWRADGRTLYSSSLDGHVIGWN 358

Query: 171 IETGQQTTTFTGHSGD---VMSLSLSPDLKTFVSGACDASSKLWDIRDGMCRQSFTGHIS 227
           + T      +   SG    V  + L    +   +   D + K+WD+      Q F+GH +
Sbjct: 359 VNTLHMIEKWKATSGRHHGVHCVCLCSSSRLLTA---DHTIKMWDLTTKNVLQEFSGHST 529

Query: 228 DINAV--SFFPSGYAFATGSDDATCRLFDLRA 257
           ++  +     PS      G  +  C +F   A
Sbjct: 530 EVIKLLPVLKPSSEQNDIGDSNLACYVFSAAA 625
>04088
          Length = 511

 Score = 34.3 bits (77), Expect = 0.078,   Method: Compositional matrix adjust.
 Identities = 23/66 (34%), Positives = 31/66 (46%), Gaps = 3/66 (4%)
 Frame = +3

Query: 151 FLDDGQI-ITSSGDTTCALWDIETGQQTTTFTGHSGDVMSLS--LSPDLKTFVSGACDAS 207
           F  DGQ  + SS D T  L D +TG+    FTGH      +   L+ +    VSG+ D  
Sbjct: 54  FTRDGQCSLVSSQDNTVRLMDKDTGEMLNEFTGHKHSQYKIDSCLNNEDTLVVSGSEDGK 233

Query: 208 SKLWDI 213
              WD+
Sbjct: 234 VYFWDL 251
>21921
          Length = 1341

 Score = 33.5 bits (75), Expect = 0.14,   Method: Compositional matrix adjust.
 Identities = 14/47 (29%), Positives = 25/47 (53%)
 Frame = -1

Query: 176 QTTTFTGHSGDVMSLSLSPDLKTFVSGACDASSKLWDIRDGMCRQSF 222
           Q   + GH+G V S+   P  +  VSG+ D + + W++  G C ++ 
Sbjct: 507 QALVYKGHTGIVRSICPDPTGQWLVSGSDDGTIRFWEVSSGRCMKTL 367
>33180
          Length = 460

 Score = 32.7 bits (73), Expect = 0.24,   Method: Compositional matrix adjust.
 Identities = 28/102 (27%), Positives = 51/102 (50%), Gaps = 7/102 (6%)
 Frame = -2

Query: 229 INAVSFFPSGYAFATGSDDATCRLFDLRADQELL-LYSHDNIICGITSVAFSK-SGRLLL 286
           I ++ F         G++D    ++D  ++Q  L + +HD+    + +VAF+  S ++L 
Sbjct: 444 IFSLMFSSDNTEIVGGANDGCLYVYDRESNQRTLKIDAHDD---DVNAVAFADDSSQILY 274

Query: 287 AGYDDFNCSVWD--ALKGGRS---GVLAGHDNRVSCLGVTDD 323
           +G DD  C VWD   L+       G++AGH + V+ +    D
Sbjct: 273 SGGDDGLCKVWDRRTLREDNPLPVGIMAGHSDGVTYIDTKGD 148
>15972
          Length = 1069

 Score = 32.3 bits (72), Expect = 0.28,   Method: Compositional matrix adjust.
 Identities = 20/80 (25%), Positives = 38/80 (47%), Gaps = 1/80 (1%)
 Frame = +3

Query: 166 CALWDIETGQQTTTFTGHSGDVMSLSLSPDLKTFVSGACDASSKLWDIRDGMCRQSFTGH 225
           C   +   G    TF+GH G V  L++ P  K  ++ + D + +LW+  +G  R +F  +
Sbjct: 183 CVCGECPPG*PERTFSGHKGPVRHLAVHPSGKLTLTVSQDRTLRLWNNMNG--RIAFISN 356

Query: 226 ISD-INAVSFFPSGYAFATG 244
           + +   +V + P G  +   
Sbjct: 357 MKEAAESVRWAPGGLYYVVA 416
>35607
          Length = 475

 Score = 32.3 bits (72), Expect = 0.30,   Method: Compositional matrix adjust.
 Identities = 32/140 (22%), Positives = 57/140 (40%)
 Frame = +2

Query: 194 PDLKTFVSGACDASSKLWDIRDGMCRQSFTGHISDINAVSFFPSGYAFATGSDDATCRLF 253
           PD     +G  D + + WD+R+G   Q      S I ++ + P+G   A G + +   + 
Sbjct: 8   PDGTKLWTGGLDNTVRSWDLREGRQLQQHD-FSSQIFSLGYCPTGDWLAVGMESSNVEVL 184

Query: 254 DLRADQELLLYSHDNIICGITSVAFSKSGRLLLAGYDDFNCSVWDALKGGRSGVLAGHDN 313
                 +  L+ H++ +    S+ F+  G+  ++   D   + W    G          +
Sbjct: 185 HHSKPDKYQLHLHESCVL---SLKFAYCGKWFVSTGKDNLLNAWRTPYGASIFQSKESSS 355

Query: 314 RVSCLGVTDDGMAVATGSWD 333
            +SC    DD   V TGS D
Sbjct: 356 VLSCDIAADDKYIV-TGSGD 412

 Score = 29.6 bits (65), Expect = 1.7,   Method: Compositional matrix adjust.
 Identities = 23/82 (28%), Positives = 41/82 (50%), Gaps = 1/82 (1%)
 Frame = +2

Query: 91  HAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTREG-NVRVSRELPGHTGYLSCC 149
           + + L  S V++  +A  G +    G DN+ + +  +T  G ++  S+E    +  LSC 
Sbjct: 206 YQLHLHESCVLSLKFAYCGKWFVSTGKDNLLNAW--RTPYGASIFQSKE---SSSVLSCD 370

Query: 150 RFLDDGQIITSSGDTTCALWDI 171
              DD  I+T SGD    L+++
Sbjct: 371 IAADDKYIVTGSGDKKATLYEV 436
>18320
          Length = 450

 Score = 32.0 bits (71), Expect = 0.36,   Method: Compositional matrix adjust.
 Identities = 26/125 (20%), Positives = 54/125 (43%), Gaps = 10/125 (8%)
 Frame = -2

Query: 226 ISDINAVSFFPSGYAFATGSDDATCRLF-DLRADQELLLYSHDNIICGITSVAFSKSGRL 284
           + ++  V F    +  A    + T R++ D     +  +Y+ D +   +  V   ++G+L
Sbjct: 416 VPEVPPVDFDGIDWQEACVERERTHRVWSDPNQHMDHFIYN-DILFAAVDVVHLMQNGQL 240

Query: 285 LLAGYDDFNCSVWDALKGGRSGVLAGHDNRVSCLGVTDDG---------MAVATGSWDSF 335
           L AG  D   ++ D  K   +   +  D ++ C+     G           + TGSWD+ 
Sbjct: 239 LAAGSRDRYLTLLDLTKYDPARPKSKKDMQLHCIDKAHSGWIWCMASLNQHLYTGSWDTK 60

Query: 336 LRIWN 340
           +++W+
Sbjct: 59  IKVWD 45
>15337
          Length = 860

 Score = 31.2 bits (69), Expect = 0.57,   Method: Compositional matrix adjust.
 Identities = 22/88 (25%), Positives = 40/88 (45%), Gaps = 3/88 (3%)
 Frame = -1

Query: 67  SRLLVSASQDGKLIIWDSYTTNKMHAIPLRSSW---VMTCAYAPSGNYVACGGLDNICSI 123
           SR L    QDG L +   +  N M  I    S+   ++   ++P G Y+  GG D++ ++
Sbjct: 293 SRYLAVVGQDGHLRV---FNYNSMELIGTMKSYFGGLLCVCWSPDGKYIVTGGEDDLVTV 123

Query: 124 YNLKTREGNVRVSRELPGHTGYLSCCRF 151
           ++   +    RV     GH  +++   F
Sbjct: 122 WSFHEK----RVVCRGHGHKSWVNVVAF 51
>07665
          Length = 435

 Score = 30.4 bits (67), Expect = 0.97,   Method: Compositional matrix adjust.
 Identities = 30/96 (31%), Positives = 44/96 (45%), Gaps = 9/96 (9%)
 Frame = -2

Query: 211 WDIRDGMCRQSFTGHISDI-NAVSFFPSGYAF--ATGSD----DATCR--LFDLRADQEL 261
           WD+ DG  +  +T   +DI NA+ F P+ Y    A G      D  C+  + +LR +   
Sbjct: 392 WDLNDG--KNLYTLEHNDIINALCFSPNRYWLCVAYGPSIKIWDLACKKTVEELRPEVVS 219

Query: 262 LLYSHDNIICGITSVAFSKSGRLLLAGYDDFNCSVW 297
                +   C   S+A+S  G+ L AGY D    VW
Sbjct: 218 PTSKAEQPQC--LSLAWSTDGQTLFAGYSDNTIRVW 117
>11915
          Length = 737

 Score = 30.4 bits (67), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 30/106 (28%), Positives = 50/106 (47%), Gaps = 11/106 (10%)
 Frame = +1

Query: 22  RKACNDA-TLVQITSNMDSVGRIQMRTRRT------LRGHLAKIYAMHWGYDSRL-LVSA 73
           R+  ND+ TLV  T ++   GRI++    T      +  H A ++ +H+  D+ L L+SA
Sbjct: 418 RQQQNDSSTLVLATGHVS--GRIKLWNCETGKLLIEMMDHKATVHDLHFAADNSLCLMSA 591

Query: 74  SQDGKLIIW---DSYTTNKMHAIPLRSSWVMTCAYAPSGNYVACGG 116
           S DG + +W   D    N    +   +    +C ++    YVA  G
Sbjct: 592 SHDGTVKLWEFDDQGDCNMYLTLRTNAKHAFSCRWSHDRRYVATAG 729

 Score = 28.5 bits (62), Expect = 4.1,   Method: Compositional matrix adjust.
 Identities = 20/75 (26%), Positives = 32/75 (42%), Gaps = 4/75 (5%)
 Frame = +1

Query: 153 DDGQIITSSGDTT--CALWDIETGQQTTTFTGHSGDVMSLSLSPDLK-TFVSGACDASSK 209
           D   ++ ++G  +    LW+ ETG+       H   V  L  + D     +S + D + K
Sbjct: 433 DSSTLVLATGHVSGRIKLWNCETGKLLIEMMDHKATVHDLHFAADNSLCLMSASHDGTVK 612

Query: 210 LWDIRD-GMCRQSFT 223
           LW+  D G C    T
Sbjct: 613 LWEFDDQGDCNMYLT 657
>17298
          Length = 476

 Score = 30.4 bits (67), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 19/84 (22%), Positives = 34/84 (40%)
 Frame = -1

Query: 170 DIETGQQTTTFTGHSGDVMSLSLSPDLKTFVSGACDASSKLWDIRDGMCRQSFTGHISDI 229
           ++ +GQ    +  H+G V  +  + +    +SG+ D + + WD R            +  
Sbjct: 254 NVASGQALRKYRDHAGTVNCVKFNEESTVILSGSLDNTVRAWDTRSRSHTPIQVLDEATD 75

Query: 230 NAVSFFPSGYAFATGSDDATCRLF 253
           +  S   S Y   TGS D   R +
Sbjct: 74  SVTSIQVSDYEILTGSADGRVRRY 3
>15745
          Length = 1183

 Score = 30.0 bits (66), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 18/61 (29%), Positives = 31/61 (50%), Gaps = 3/61 (4%)
 Frame = +2

Query: 158 ITSSGDTTCALWDIETGQQTTTFTGHSGD-VMSLSLSPDLKTFVSGAC--DASSKLWDIR 214
           I ++ + T   WD+ + QQT    G  G  V  L  +P+ + +++ +C  D   K WD R
Sbjct: 629 IATANEATIRGWDLRSKQQTYQMEGAHGQLVRDLDFNPNRQYYLA-SCGDDCRVKFWDTR 805

Query: 215 D 215
           +
Sbjct: 806 N 808
>07781
          Length = 1269

 Score = 30.0 bits (66), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 28/114 (24%), Positives = 52/114 (45%), Gaps = 7/114 (6%)
 Frame = -2

Query: 156 QIITSSGDTTCALWDIE--TGQQTTTFTGHSGDVMSLSLSP-DLKTFVSGACDASSKLWD 212
           ++ITS       ++++E  T ++T+ +  H  +    +    + +   SG+ D   K+WD
Sbjct: 884 RVITSDSAGNLTVFEVESTTVRETSQWRAHDFEAWICAFDQWNTELIYSGSDDCKLKVWD 705

Query: 213 IRDG----MCRQSFTGHISDINAVSFFPSGYAFATGSDDATCRLFDLRADQELL 262
           +R G    +    FT  ++ I +       +  A GS D   RLFD R  ++ L
Sbjct: 704 LRVGTTPVLTNSRFTMGVTSIQSCP--QREHLLAVGSYDENLRLFDTRHMRQPL 549
>19140
          Length = 573

 Score = 29.6 bits (65), Expect = 1.7,   Method: Compositional matrix adjust.
 Identities = 19/77 (24%), Positives = 34/77 (44%)
 Frame = -3

Query: 180 FTGHSGDVMSLSLSPDLKTFVSGACDASSKLWDIRDGMCRQSFTGHISDINAVSFFPSGY 239
             GH+ +V +L L+ D    +SG+ D + +LW +    C  +F  H   + A+    S  
Sbjct: 499 LKGHTDNVKALVLNRDGTQCLSGSSDGTIRLWSLGQQRCVATFRVHDEGVWALQANESFT 320

Query: 240 AFATGSDDATCRLFDLR 256
              +G  D      D++
Sbjct: 319 TLYSGGRDHQVWATDIK 269
>12140
          Length = 727

 Score = 28.9 bits (63), Expect = 3.3,   Method: Compositional matrix adjust.
 Identities = 24/89 (26%), Positives = 40/89 (44%), Gaps = 13/89 (14%)
 Frame = +2

Query: 49  RTLRGHLAKIYAMHW----GYDSRLLVSASQDGKLIIW------DSYTT---NKMHAIPL 95
           + L GH   +  + W    G    ++ S SQD ++IIW      + +T+   NK   +  
Sbjct: 338 QKLEGHSDWVRDVAWAPSIGLPRNVIASCSQDCRVIIWTNDGSSNQWTSRILNKFSDVVW 517

Query: 96  RSSWVMTCAYAPSGNYVACGGLDNICSIY 124
             SW +T      GN +A  G DN  +++
Sbjct: 518 HVSWSVT------GNILAVSGGDNKVTLW 586

 Score = 27.7 bits (60), Expect = 6.7,   Method: Compositional matrix adjust.
 Identities = 16/44 (36%), Positives = 22/44 (50%), Gaps = 2/44 (4%)
 Frame = +2

Query: 196 LKTFVSGACDASSKLW--DIRDGMCRQSFTGHISDINAVSFFPS 237
           +K FVSG CD   K+W  D    +  Q   GH   +  V++ PS
Sbjct: 260 VKRFVSGGCDNLVKIWREDETGWVEDQKLEGHSDWVRDVAWAPS 391
>20662
          Length = 1220

 Score = 28.5 bits (62), Expect = 3.6,   Method: Compositional matrix adjust.
 Identities = 23/72 (31%), Positives = 36/72 (50%), Gaps = 4/72 (5%)
 Frame = +2

Query: 66  DSRLLVSASQDGKLIIWDSYTTNKMHAIPLRSS-WVMTCA-YAPSG-NYVACGGLDNICS 122
           +  L +S SQDGK+++WD   +     +P  SS +  TC  + P+  N  A G      S
Sbjct: 545 EPALFLSCSQDGKIVLWDVRESKPATCLPKCSSGFKPTCVQWQPNARNMYAVGDEGGHVS 724

Query: 123 IYNLK-TREGNV 133
           + +L+   E NV
Sbjct: 725 VQDLRMVVEKNV 760
>16477
          Length = 892

 Score = 28.5 bits (62), Expect = 4.1,   Method: Compositional matrix adjust.
 Identities = 19/63 (30%), Positives = 26/63 (41%)
 Frame = -1

Query: 79  LIIWDSYTTNKMHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRE 138
           L I+  Y T    AI    S+++ C Y    NYV CG    + + YN       +     
Sbjct: 760 LYIYARYNTASQLAIISNGSFLIKCIYFSISNYVHCGFYC*LITQYNFFCLSLTLH*VIL 581

Query: 139 LPG 141
           LPG
Sbjct: 580 LPG 572
>22113
          Length = 614

 Score = 28.5 bits (62), Expect = 4.5,   Method: Compositional matrix adjust.
 Identities = 22/82 (26%), Positives = 41/82 (50%), Gaps = 1/82 (1%)
 Frame = +3

Query: 91  HAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTREG-NVRVSRELPGHTGYLSCC 149
           + + L  S V++  +A  G +    G DN+ + +  +T  G ++  S+E    +  LSC 
Sbjct: 84  YQLHLHESCVLSLRFATCGKWFVSTGKDNLLNAW--RTPYGASIFQSKET---SSVLSCD 248

Query: 150 RFLDDGQIITSSGDTTCALWDI 171
              DD  I+T SGD    ++++
Sbjct: 249 ISTDDKYIVTGSGDKKATVYEV 314
>27525
          Length = 828

 Score = 28.1 bits (61), Expect = 4.8,   Method: Compositional matrix adjust.
 Identities = 14/40 (35%), Positives = 19/40 (47%)
 Frame = +2

Query: 219 RQSFTGHISDINAVSFFPSGYAFATGSDDATCRLFDLRAD 258
           R SF    + INA+SF P G   A G  D    ++ +  D
Sbjct: 47  RNSFQVGQAQINAISFSPDGSQLAVGCHDGFVHVYVVHED 166
>04358
          Length = 2430

 Score = 28.1 bits (61), Expect = 5.1,   Method: Compositional matrix adjust.
 Identities = 12/42 (28%), Positives = 23/42 (54%), Gaps = 1/42 (2%)
 Frame = +1

Query: 44   QMRTRRTLRG-HLAKIYAMHWGYDSRLLVSASQDGKLIIWDS 84
            +++  R+L G H   +  +HW   ++ LV+  +D  L +W S
Sbjct: 2110 EVKVVRSLSGGHTDTVRCLHWDKQTQTLVTGGEDSMLCLWSS 2235

 Score = 27.7 bits (60), Expect = 6.1,   Method: Compositional matrix adjust.
 Identities = 58/278 (20%), Positives = 95/278 (34%), Gaps = 76/278 (27%)
 Frame = +1

Query: 139  LPGHTGYLSCCRFL--DDGQIITSSGDTTCALWDIE----------TGQQTTTFT----- 181
            L GH   +S  RFL  D G I+T+S D T  +WD            +G+Q T  +     
Sbjct: 1408 LTGHDDVISSIRFLHTDPGLIMTASHDHTVRIWDPRASVSKEVQRFSGEQNTKCSVLSCD 1587

Query: 182  -------------------------------------GHSGDVMSLSLSP-DLKTFVSGA 203
                                                  H  D+  +   P   KT ++G+
Sbjct: 1588 VNISDRVLCAGTEMSNDDAYLLFWDRRKDKLLGCYEDSHHDDITQVHFGPTSEKTLLTGS 1767

Query: 204  CDASSKLWDI----RDGMCRQSFTGHIS------------DINAVSFFPSGYAFATGSDD 247
             D    ++D+     D     ++    +             + A++   S + + T  D+
Sbjct: 1768 TDGLVNVFDVMQTTEDDALMSTYNTEATVERAGWCGPQSQQVYAITHMLSWHVWDTEKDE 1947

Query: 248  ATCRLFDLRADQELLLYSHDNIICGITSVAFSKSGRLLLAGYDDFNCSVWD-----ALKG 302
               +L DL  +Q+L      + +        S S   L+AG    +  V D      +K 
Sbjct: 1948 DVQQLTDL--EQKLQGQCQADYLVDCIPANQSTSPPCLVAGTHTGDLHVLDLSDLEEVKV 2121

Query: 303  GRSGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLRIWN 340
             RS +  GH + V CL        + TG  DS L +W+
Sbjct: 2122 VRS-LSGGHTDTVRCLHWDKQTQTLVTGGEDSMLCLWS 2232
>05907
          Length = 954

 Score = 27.7 bits (60), Expect = 7.6,   Method: Compositional matrix adjust.
 Identities = 16/42 (38%), Positives = 18/42 (42%), Gaps = 6/42 (14%)
 Frame = -3

Query: 215 DGMCRQSF------TGHISDINAVSFFPSGYAFATGSDDATC 250
           D  CR SF      TGH    +   F P G  F T S+ A C
Sbjct: 598 DKXCRDSFVLIVI*TGHFPYYHKELFCPGGCCFKTCSETAQC 473
>27681
          Length = 465

 Score = 27.3 bits (59), Expect = 8.1,   Method: Compositional matrix adjust.
 Identities = 25/107 (23%), Positives = 49/107 (45%)
 Frame = +2

Query: 233 SFFPSGYAFATGSDDATCRLFDLRADQELLLYSHDNIICGITSVAFSKSGRLLLAGYDDF 292
           ++ P+    A+GS D+T R++++                  TS   + + +L+L      
Sbjct: 14  AWNPTNDLLASGSGDSTARIWNM------------------TSETPNNANQLVLR----- 124

Query: 293 NCSVWDALKGGRSGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLRIW 339
           +C     ++ G + V +  D  V+ L    +G  +ATGS+D + R+W
Sbjct: 125 HC-----IQKGGTEVPSNKD--VTSLDWNSEGTLLATGSYDGYARLW 244
>38177
          Length = 430

 Score = 27.3 bits (59), Expect = 8.4,   Method: Compositional matrix adjust.
 Identities = 16/50 (32%), Positives = 23/50 (46%), Gaps = 4/50 (8%)
 Frame = +3

Query: 51  LRGHLAKIYAMHWGYDSRLLVSASQDGKLIIWDSYTTN-KM---HAIPLR 96
           L+ H   + AM W    + +V+A   G +  W S   N KM   H  P+R
Sbjct: 102 LQAHDVSVRAMRWSNHDQWMVTADHSGYIKYWQSNMNNVKMFQGHKEPIR 251
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|80978937|ref|NP_001032213.1| centaurin, gamma 2
isoform 2 [Mus musculus]
         (804 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

02351                                                                 277   1e-74
32987                                                                  64   6e-12
13462                                                                  55   1e-07
08428                                                                  51   2e-06
14456                                                                  50   5e-06
00858                                                                  49   5e-06
05924                                                                  49   9e-06
11257                                                                  49   9e-06
09292                                                                  48   2e-05
36482                                                                  45   9e-05
07465                                                                  43   5e-04
34468                                                                  43   5e-04
09180                                                                  42   0.001
12417                                                                  42   0.001
35806                                                                  40   0.003
21532                                                                  40   0.004
08473                                                                  39   0.011
14005                                                                  39   0.012
12339                                                                  38   0.017
06253                                                                  38   0.020
00540                                                                  37   0.022
13745                                                                  36   0.054
02114                                                                  36   0.075
19166                                                                  35   0.13 
11295                                                                  35   0.14 
20036                                                                  34   0.25 
09204                                                                  33   0.34 
32770                                                                  33   0.51 
20884                                                                  33   0.61 
16561                                                                  32   0.93 
13358                                                                  32   0.97 
00552                                                                  32   1.1  
25470                                                                  32   1.1  
27108                                                                  31   2.5  
01398                                                                  30   2.6  
02055                                                                  30   3.8  
09214                                                                  30   4.0  
33484                                                                  30   4.8  
34789                                                                  30   5.6  
27067                                                                  29   5.7  
14764                                                                  29   6.4  
15772                                                                  29   8.3  
>02351
          Length = 939

 Score =  277 bits (709), Expect = 1e-74,   Method: Compositional matrix adjust.
 Identities = 125/215 (58%), Positives = 159/215 (73%)
 Frame = +3

Query: 561 SIRNMRGNSHCVDCDTQNPNWASLNLGALMCIECSGIHRNLGTHLSRVRSLDLDDWPMEL 620
           +IR  RGN+ CVDC T +P+WAS+NLGA+MCIEC G+HRN+GTH+SRVRSLDLDDWP E+
Sbjct: 3   TIRTTRGNTICVDCGTPSPSWASINLGAVMCIECCGVHRNIGTHISRVRSLDLDDWPPEV 182

Query: 621 IKVMSSIGNELANSVWEEGSQGRTKPSLDSTREEKERWIRAKYEQKLFLAPLPCTEFSLG 680
            KVM+SIGN +ANSVWE  ++GR+KP+  S REEKE+WI+AKYE K FL PLP  +  + 
Sbjct: 183 TKVMTSIGNYVANSVWEANTKGRSKPTSSSNREEKEQWIKAKYEAKEFLPPLPYIDIPIN 362

Query: 681 QQLLRATAEEDLRTVILLLAHGSRDEVNETCGEGDGRTALHLACRKGNVVLAQLLIWYGV 740
           QQL+ A   ED+R +I++L H + D++N   G+ DGRTALH+A   GNVV  QLL+WY  
Sbjct: 363 QQLIDALVREDIRNIIIILGHAASDDINSPYGKDDGRTALHIAAALGNVVYVQLLLWYCA 542

Query: 741 DVMARDAHGNTALAYARQASSQECIDVLLQYGCPD 775
           +V   D  G  AL YAR + S EC D+L   GCPD
Sbjct: 543 NVKVVDHEGRNALWYARTSGSVECTDLLAAAGCPD 647
>32987
          Length = 368

 Score = 63.5 bits (153), Expect(2) = 6e-12,   Method: Compositional matrix adjust.
 Identities = 38/87 (43%), Positives = 53/87 (60%)
 Frame = +2

Query: 645 KPSLDSTREEKERWIRAKYEQKLFLAPLPCTEFSLGQQLLRATAEEDLRTVILLLAHGSR 704
           KP L+S  ++KE WIR+KYE++ FL PLPC  + + QQL+ A    D+R VIL LA  + 
Sbjct: 35  KPELNSPAKDKEEWIRSKYERREFLPPLPCPWWPIQQQLIDAIKRRDIRQVILCLAIATE 214

Query: 705 DEVNETCGEGDGRTALHLACRKGNVVL 731
            EVN +    D R  +H+A   G + L
Sbjct: 215 AEVNASYNRTDPRAPIHIAAAIGYICL 295

 Score = 25.8 bits (55), Expect(2) = 6e-12,   Method: Composition-based stats.
 Identities = 12/26 (46%), Positives = 14/26 (53%)
 Frame = +3

Query: 730 VLAQLLIWYGVDVMARDAHGNTALAY 755
           V  QLLIWY   V  +D +G  A  Y
Sbjct: 291 VCLQLLIWYKGQVDLKDVNGRNAYYY 368
>13462
          Length = 1388

 Score = 55.1 bits (131), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 34/82 (41%), Positives = 48/82 (58%)
 Frame = +3

Query: 691 DLRTVILLLAHGSRDEVNETCGEGDGRTALHLACRKGNVVLAQLLIWYGVDVMARDAHGN 750
           +L  V +LLA+G++  V +     DG TALHLAC + NV + +LL+ +G DV   D    
Sbjct: 219 NLGIVSMLLAYGAQPNVQDE----DGNTALHLACSESNVDVVRLLLEWGGDVAVADIDNE 386

Query: 751 TALAYARQASSQECIDVLLQYG 772
           T L  A  A+S E +D+LL  G
Sbjct: 387 TPLVRACLANSVELVDLLLHAG 452

 Score = 32.3 bits (72), Expect = 0.75,   Method: Compositional matrix adjust.
 Identities = 16/47 (34%), Positives = 27/47 (57%)
 Frame = +3

Query: 726 KGNVVLAQLLIWYGVDVMARDAHGNTALAYARQASSQECIDVLLQYG 772
            GN+ +  +L+ YG     +D  GNTAL  A   S+ + + +LL++G
Sbjct: 213 NGNLGIVSMLLAYGAQPNVQDEDGNTALHLACSESNVDVVRLLLEWG 353

 Score = 31.6 bits (70), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 32/86 (37%), Positives = 38/86 (44%), Gaps = 8/86 (9%)
 Frame = +3

Query: 695 VILLLAHGSRDEVNETCGEGDGRTALHLACRKGNVVLAQLLIWYGVDVMARDAHGNT--- 751
           V LLL  GS    N     G G T LH AC+   V   +LL+ YG DV   D    +   
Sbjct: 708 VRLLLLWGS----NPNLVTGTGDTPLHFACQTFAVSKVRLLLMYGADVNQIDGTHTSPLI 875

Query: 752 -ALAYARQ----ASSQECIDVLLQYG 772
            AL   RQ    AS  + I +LL  G
Sbjct: 876 AALTTRRQPQNDASYLDLIRLLLAAG 953
>08428
          Length = 1109

 Score = 50.8 bits (120), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 42/166 (25%), Positives = 83/166 (50%), Gaps = 7/166 (4%)
 Frame = -3

Query: 71   ELKVGIVGNLASGKSALVHRYLTGTY-VQEESPEGGRF-KKEIVVDGQSYLLLIRDEGGP 128
            ++KV ++G+   GKS++V R++TG+Y   +ES  G  F  K +VVDG  Y   I D  G 
Sbjct: 1071 DVKVCLLGDSGVGKSSIVLRFVTGSYRPSQESTIGASFMSKSLVVDGAGYRFQIWDTAGQ 892

Query: 129  PEAQ-----FAMWVDAVIFVFSLEDEISFQTVYHYYSRMANYRNTSEIPLVLVGTQDAIS 183
             + +     +     A + V+ +    +F++V  +   + ++     I L + G +  + 
Sbjct: 891  EKFRALAPMYYRGAAAAVIVYDVTRPRTFKSVKSWIQELRSF-GPPNIVLAIAGNKCDLE 715

Query: 184  STNPRVIDDVRARKLSNDLKRCTYYETCATYGLNVERVFQDVAQKI 229
                 V  D  A++ ++ +    + ET A   +NVE +F ++A+++
Sbjct: 714  ELREVVEKD--AQEYASSIS-AIFGETSAMTAVNVEEMFTELARQL 586
>14456
          Length = 1867

 Score = 49.7 bits (117), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 45/177 (25%), Positives = 81/177 (45%), Gaps = 21/177 (11%)
 Frame = -1

Query: 83   GKSALVHRYLTGTY-VQEESPEGGRF-KKEIVVDGQSYLLLIRDEGGPPEAQ-----FAM 135
            GKS+L++R+++  +  Q     G  F  K++VVD ++Y + I D  G    +     F  
Sbjct: 1105 GKSSLMNRFVSNKFDAQSFHTIGVEFLNKDVVVDDETYTMQIWDTAGQERFKSLRTPFYR 926

Query: 136  WVDAVIFVFSLEDEISFQTV------YHYYSRMANYRNTSEIPLVLVGTQDAISSTNPRV 189
              D  +  FS++   SF+ +      + YY   A+ ++    P V++G +          
Sbjct: 925  GADCCLLTFSVDSMQSFRNLSMWRKEFLYY---ADIQDGVTFPFVVLGNKI--------- 782

Query: 190  IDDVRARKLSNDLKR--CT------YYETCATYGLNVERVFQDVAQKIVATRKKQQL 238
              DV  R+++N+  R  CT      Y+ET A    NVE+ F    Q++     +Q++
Sbjct: 781  --DVEGRQVTNEEARSWCTANSNAPYFETSAKDATNVEKAFLAAVQRLREVEDQQEV 617
>00858
          Length = 1658

 Score = 49.3 bits (116), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 47/182 (25%), Positives = 83/182 (45%), Gaps = 6/182 (3%)
 Frame = -2

Query: 54   EDAFVNSQEWTLSRSVPELKVGIVGNLASGKSALVHRYLTGTYVQEESP-EGGRFKKEIV 112
            ED    ++    +  + E K+ +VG    GKSAL  +     +V+E  P      +K++V
Sbjct: 1642 EDCLRKTKRELYTTQMTEYKLVVVGAGGVGKSALTIQLXQNHFVEEYDPTXEDSXRKQVV 1463

Query: 113  VDGQSYLLLIRDEGGPPEA-----QFAMWVDAVIFVFSLEDEISFQTVYHYYSRMANYRN 167
            +DG++ LL I D  G  E      Q     +  + VF++ +  SF+ +  Y  ++   ++
Sbjct: 1462 IDGETCLLDILDTAGQEEXSAMRDQCMRTGEGFLCVFAVXNLKSFEDINQYREQIKRVKD 1283

Query: 168  TSEIPLVLVGTQDAISSTNPRVIDDVRARKLSNDLKRCTYYETCATYGLNVERVFQDVAQ 227
              E+P+VLVG +  +   N     + R  K   +L    Y ET A     V+  F  + +
Sbjct: 1282 ADEVPMVLVGNKVDLPIRNV----EQRQGKHMAELYHIPYVETSAKTRQGVDDAFYTLVR 1115

Query: 228  KI 229
            +I
Sbjct: 1114 EI 1109
>05924
          Length = 704

 Score = 48.9 bits (115), Expect = 9e-06,   Method: Composition-based stats.
 Identities = 34/87 (39%), Positives = 42/87 (48%)
 Frame = +1

Query: 686 ATAEEDLRTVILLLAHGSRDEVNETCGEGDGRTALHLACRKGNVVLAQLLIWYGVDVMAR 745
           + A EDL  V +L+  G+    N      DGRTALHLACR G   + Q+LI  G DV  R
Sbjct: 91  SMASEDL--VQMLIKAGA----NANSTNQDGRTALHLACRGGYTNIVQILIAAGTDVNRR 252

Query: 746 DAHGNTALAYARQASSQECIDVLLQYG 772
              G T L  A      E +  L+  G
Sbjct: 253 TVDGKTCLHVAVWRGHTEVVVKLVNAG 333

 Score = 32.3 bits (72), Expect = 0.68,   Method: Composition-based stats.
 Identities = 18/58 (31%), Positives = 32/58 (55%)
 Frame = +1

Query: 715 DGRTALHLACRKGNVVLAQLLIWYGVDVMARDAHGNTALAYARQASSQECIDVLLQYG 772
           DG+T LH+A  +G+  +   L+  G DV   D+ G + L +A +++    + VL+  G
Sbjct: 259 DGKTCLHVAVWRGHTEVVVKLVNAGADVNIPDSVGCSPLYWAARSNYTAILTVLVNAG 432
>11257
          Length = 1102

 Score = 48.5 bits (114), Expect = 9e-06,   Method: Compositional matrix adjust.
 Identities = 32/129 (24%), Positives = 60/129 (46%), Gaps = 8/129 (6%)
 Frame = -2

Query: 109  KEIVVDGQSYLLLIRDEGGPPEAQ-----FAMWVDAVIFVFSLEDEISFQTVYHYYSRMA 163
            K++VVDG+++ + I D  G    +     F    D  +  FS+++  S Q++  +Y    
Sbjct: 1053 KDVVVDGETFTMQIWDTAGQERYKSLRTPFYRGTDCCLLTFSVDNLKSLQSLSDWYDEFV 874

Query: 164  NY---RNTSEIPLVLVGTQDAISSTNPRVIDDVRARKLSNDLKRCTYYETCATYGLNVER 220
            NY   ++++  P V++G +  I     R +    A           Y+ET A   LNV++
Sbjct: 873  NYADIQDSASFPFVIIGNKADIEE---REVSSEDAYNWCRTHGNLPYFETSAKDSLNVQQ 703

Query: 221  VFQDVAQKI 229
             F  V +++
Sbjct: 702  AFLAVVRRL 676
>09292
          Length = 1486

 Score = 47.8 bits (112), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 31/79 (39%), Positives = 47/79 (59%), Gaps = 1/79 (1%)
 Frame = -2

Query: 695  VILLLAHGSRDEVNETCGEGDGRTALHLACRKGNVVLAQLLIWYGVDVMARDAHGNTALA 754
            V LLL HG+   VN   G    ++ LH+ACR GN+ +A+ +I  G +V A D  GNT L 
Sbjct: 1029 VQLLLVHGA--AVNSLPGT---KSPLHIACRNGNIEMARTVIIAGANVNAVDKDGNTPLH 865

Query: 755  YA-RQASSQECIDVLLQYG 772
             + R  SS + + +L+++G
Sbjct: 864  ISVRAPSSAQLVRLLIRFG 808

 Score = 33.1 bits (74), Expect = 0.41,   Method: Compositional matrix adjust.
 Identities = 25/82 (30%), Positives = 40/82 (48%)
 Frame = -2

Query: 695 VILLLAHGSRDEVNETCGEGDGRTALHLACRKGNVVLAQLLIWYGVDVMARDAHGNTALA 754
           ++ L+  GS D VN    +G     LHLAC K  + +A+ L+ +G +V     +G T L 
Sbjct: 636 IVRLVLQGSSD-VNSP--DGRNNAPLHLACMKQCIGIARCLLRHGANVNVSGYNGRTPLH 466

Query: 755 YARQASSQECIDVLLQYGCPDE 776
            A    + E + +L   G  D+
Sbjct: 465 IAISHHNLELVLLLYMCGANDQ 400
>36482
          Length = 686

 Score = 45.4 bits (106), Expect = 9e-05,   Method: Compositional matrix adjust.
 Identities = 41/184 (22%), Positives = 78/184 (42%), Gaps = 8/184 (4%)
 Frame = +2

Query: 87  LVHRYLTGTYVQEESPE-GGRFKKEIVVDGQSYLLLIRDEGG----PPEAQFAMWVDAVI 141
           L  R+LT  ++ E  P     +K   V++     L I D  G    P +  +A+W D  +
Sbjct: 2   LTVRFLTRRFIGEYCPTLESVYKYHTVIEDDDVRLEILDTAGQGTYPWKEGYALWADCFV 181

Query: 142 FVFSLEDEISFQTVYHYYSRMANYRNTSEIPLVLVGTQDAISSTNPRVIDDVRARKLSND 201
           FV+S+ D  S++ +     ++ + R ++ +  VL   +  +   + R +       L+ +
Sbjct: 182 FVYSINDRQSYEELVQVKRQVESVRKSTSLTAVLAANKTDL--LHDRQVTQKEGEDLAEE 355

Query: 202 LKRCTYYETCATYGLNVERV---FQDVAQKIVATRKKQQLSIGPCKSLPNSPSHSSVCSA 258
           +  C  YE  A+ G  +E +   F D+ ++    RK +Q   G  +   NS         
Sbjct: 356 IG-CRLYEVSASEGSQMEAITSMFHDLYREF---RKHKQQREGRQRKTSNSAKFKQAIQK 523

Query: 259 QVSA 262
            +S 
Sbjct: 524 VISG 535
>07465
          Length = 1103

 Score = 43.1 bits (100), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 37/151 (24%), Positives = 68/151 (45%), Gaps = 7/151 (4%)
 Frame = +3

Query: 85  SALVHRYLTGTYVQEESPEGG--RFKKEIVVDGQSYLLLIRDEGGPPEAQ-----FAMWV 137
           S+++ RY  G + ++     G    +++I V G+   L++ D  G  E       +    
Sbjct: 240 SSMIQRYCKGIFTKDYKKTIGVDFLERQIEVGGEDVRLMLWDTAGQEEFDAITKAYYRGA 419

Query: 138 DAVIFVFSLEDEISFQTVYHYYSRMANYRNTSEIPLVLVGTQDAISSTNPRVIDDVRARK 197
            A +  FS  D  SF+ +  +  ++ +     EI +V+V  Q+ I   +  V+    A  
Sbjct: 420 QACVLAFSTVDRDSFEALETWKRKVED--EVGEIGMVIV--QNKIDLIDDAVVRPEEAEN 587

Query: 198 LSNDLKRCTYYETCATYGLNVERVFQDVAQK 228
           L+  L R  +Y T     +NV+ VF+ +A K
Sbjct: 588 LAKKL-RLRFYRTSVKENMNVDEVFRYLADK 677
>34468
          Length = 1502

 Score = 42.7 bits (99), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 52/211 (24%), Positives = 90/211 (42%), Gaps = 22/211 (10%)
 Frame = +1

Query: 72  LKVGIVGNLASGKSALVHRYLTGTYVQE-ESPEGGRFK-KEIVVDGQSYLLLIRDEGGPP 129
            K+ ++G+   GK+ L +R+  G +  + E+  G  F+ K I VD +   L + D  G  
Sbjct: 496 FKIIVIGDSNVGKTCLTYRFCLGKFPDKTEATIGVDFREKSIQVDSEHLKLQLWDTAGQE 675

Query: 130 EAQFAMW------VDAVIFVFSLEDEISFQTVYHYYSRMANYRNTSEIPLVLVGTQ-DAI 182
             + +M       V AV+FV+ +    SF+ +  +      +  T  IP +LVG + D +
Sbjct: 676 RFRKSMVQHYYRNVHAVVFVYDMTKMSSFENMPAWIEECDRHNLTKYIPRILVGNKCDVV 855

Query: 183 SSTNPRVIDDVRARKLSNDLKRCTYYETCAT---YGLNVERVFQDVAQKIVATRKKQ--- 236
                  ++   A+K + D      +ET A       +V+ +F  VA K+  ++      
Sbjct: 856 ERI---AVNTNLAQKFA-DAHNMPLFETSAKDDEKANHVDAIFMTVAHKLKXSKPMMPAH 1023

Query: 237 -------QLSIGPCKSLPNSPSHSSVCSAQV 260
                   +S G    L  SP H  + SA V
Sbjct: 1024LSEMVPGDVSHGDLVHLRGSPRHRGLESATV 1116
>09180
          Length = 610

 Score = 42.0 bits (97), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 21/58 (36%), Positives = 34/58 (58%)
 Frame = +3

Query: 716 GRTALHLACRKGNVVLAQLLIWYGVDVMARDAHGNTALAYARQASSQECIDVLLQYGC 773
           G TALH++  KG + +  +L+  GVD+ A+DA G T+L  A     ++   VL+ + C
Sbjct: 165 GATALHVSAAKGYINVMNVLLQAGVDINAQDADGWTSLHAAVHWGQEDSCQVLVDHFC 338
>12417
          Length = 954

 Score = 41.6 bits (96), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 21/56 (37%), Positives = 31/56 (55%)
 Frame = +2

Query: 716 GRTALHLACRKGNVVLAQLLIWYGVDVMARDAHGNTALAYARQASSQECIDVLLQY 771
           GRT LH A  +G+  +  LL+  G D+ A D +G+TAL+ A Q   + C   L  +
Sbjct: 332 GRTPLHXASAQGHGHIVDLLLEKGADIDAEDDYGDTALSIADQFGFKSCGRXLFLF 499
>35806
          Length = 792

 Score = 40.0 bits (92), Expect = 0.003,   Method: Composition-based stats.
 Identities = 28/90 (31%), Positives = 47/90 (52%), Gaps = 5/90 (5%)
 Frame = -2

Query: 77  VGNLASGKSALVHRYLTGTYVQEESPEGGRFKKEIVVDGQSYLLLIRDEGGPPEAQFAMW 136
           +G+L +G   L+H+ L    +Q+  PE      E  +D +  L+LIR +  PP AQ A +
Sbjct: 299 LGDLDNGSDKLLHKVL----LQQVGPEMVDKVDEQTLDVRPILVLIRHDHQPPVAQRAQF 132

Query: 137 VDAVIFVF-----SLEDEISFQTVYHYYSR 161
           V  V+F+      +L+D + F  V+  + R
Sbjct: 131 V*RVVFLLKVQSQNLDDVVDFCVVHDLFVR 42
>21532
          Length = 460

 Score = 40.0 bits (92), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 23/75 (30%), Positives = 37/75 (49%), Gaps = 11/75 (14%)
 Frame = -1

Query: 717 RTALHLACRKGNVVLAQLLIWYGVDVMARDAHGNTALAYARQASSQECIDVLLQ------ 770
            T LHLA ++G+  + +LL+ +  D+ A++  G+  L+ ARQ   +  + VL Q      
Sbjct: 274 NTPLHLASQEGHTAIVELLVEHKADLAAKNDSGHNPLSLARQYKHENVVAVLQQAENTEP 95

Query: 771 -----YGCPDERFVL 780
                Y C   RF L
Sbjct: 94  VIPTNYDCTVARFRL 50
>08473
          Length = 942

 Score = 38.5 bits (88), Expect = 0.011,   Method: Compositional matrix adjust.
 Identities = 22/66 (33%), Positives = 35/66 (53%)
 Frame = -1

Query: 707 VNETCGEGDGRTALHLACRKGNVVLAQLLIWYGVDVMARDAHGNTALAYARQASSQECID 766
            N TC E  G+T L  A  +G + + +LL+  G +V A D    T L  A +  ++E ++
Sbjct: 846 ANPTCMEMGGKTPLFYAAHRGEISICKLLVDKGANVNAADKMLITPLMVAAREGNREAVE 667

Query: 767 VLLQYG 772
            LL+ G
Sbjct: 666 FLLKRG 649
>14005
          Length = 1745

 Score = 38.5 bits (88), Expect = 0.012,   Method: Compositional matrix adjust.
 Identities = 29/92 (31%), Positives = 46/92 (50%)
 Frame = -1

Query: 680  GQQLLRATAEEDLRTVILLLAHGSRDEVNETCGEGDGRTALHLACRKGNVVLAQLLIWYG 739
            G+  L    + D   V LLL   S   VN +C +    T +H AC++ N+ L + L+ +G
Sbjct: 1442 GKTPLVVACKNDKAEVALLLIR-SGANVNVSC-DITANTPVHFACQRPNIELLKRLVLHG 1269

Query: 740  VDVMARDAHGNTALAYARQASSQECIDVLLQY 771
             DV   +A G+TAL  A     ++ +  LL +
Sbjct: 1268 ADVDKPNAKGHTALHVASVRGFKQHVIYLLDF 1173

 Score = 35.8 bits (81), Expect = 0.063,   Method: Compositional matrix adjust.
 Identities = 27/83 (32%), Positives = 42/83 (50%), Gaps = 1/83 (1%)
 Frame = -1

Query: 691  DLRTVILLLAHGSRDEVNETCGEGDGRTALHLACRKGNVVLAQLLIWYGVDV-MARDAHG 749
            D R  + LL HG+  E        DG+T L +AC+     +A LLI  G +V ++ D   
Sbjct: 1505 DPRIALYLLRHGANKESRTV----DGKTPLVVACKNDKAEVALLLIRSGANVNVSCDITA 1338

Query: 750  NTALAYARQASSQECIDVLLQYG 772
            NT + +A Q  + E +  L+ +G
Sbjct: 1337 NTPVHFACQRPNIELLKRLVLHG 1269

 Score = 29.6 bits (65), Expect = 5.2,   Method: Compositional matrix adjust.
 Identities = 20/56 (35%), Positives = 32/56 (57%), Gaps = 1/56 (1%)
 Frame = -1

Query: 718  TALHLACRKGNV-VLAQLLIWYGVDVMARDAHGNTALAYARQASSQECIDVLLQYG 772
            T L +A R G++ V+++LL   G+DV  RD     AL +A   +  E +  L++YG
Sbjct: 1739 TPLIIASRMGHLAVVSELLKVPGIDVNERDEKLRPALYFACMGNDIELVKQLVRYG 1572

 Score = 29.3 bits (64), Expect = 6.8,   Method: Compositional matrix adjust.
 Identities = 23/89 (25%), Positives = 39/89 (43%)
 Frame = -1

Query: 680  GQQLLRATAEEDLRTVILLLAHGSRDEVNETCGEGDGRTALHLACRKGNVVLAQLLIWYG 739
            G   L   +    +  ++ L      EVN    +G+   ALH+ACR  +  L +LL+  G
Sbjct: 1241 GHTALHVASVRGFKQHVIYLLDFCDAEVNAATLKGN--NALHIACRGKHADLVELLLHKG 1068

Query: 740  VDVMARDAHGNTALAYARQASSQECIDVL 768
             +   R+  G     +  + S+  C +VL
Sbjct: 1067 ANPAQRNQRG-----WTPRNSAGRCXEVL 996
>12339
          Length = 578

 Score = 37.7 bits (86), Expect = 0.017,   Method: Composition-based stats.
 Identities = 26/113 (23%), Positives = 52/113 (46%), Gaps = 3/113 (2%)
 Frame = -2

Query: 133 FAMWVDAVIFVFSLEDEISFQTVYHY---YSRMANYRNTSEIPLVLVGTQDAISSTNPRV 189
           F    D  I V+ + +  +F ++  +   +   A+ R+    P V++G +  + +   RV
Sbjct: 547 FYRGADCCILVYDVTEXKTFDSLDSWQREFLNQASPRDPEHFPFVVIGNKIDLDN---RV 377

Query: 190 IDDVRARKLSNDLKRCTYYETCATYGLNVERVFQDVAQKIVATRKKQQLSIGP 242
           +   R +   +      Y+ET A   +NVE+ FQ VA+  +A   + ++   P
Sbjct: 376 VTAKRGQGWCSTKGGIPYFETSAKEAINVEQAFQTVAKNALAQESEVEIDDFP 218
>06253
          Length = 1049

 Score = 37.7 bits (86), Expect = 0.020,   Method: Compositional matrix adjust.
 Identities = 25/68 (36%), Positives = 32/68 (47%), Gaps = 2/68 (2%)
 Frame = -1

Query: 707 VNETCGEGDGR--TALHLACRKGNVVLAQLLIWYGVDVMARDAHGNTALAYARQASSQEC 764
           +N  C   DGR  T LHLA       + QLL+ +G DV A+D  G   L  A      E 
Sbjct: 620 LNVNCHASDGRKSTPLHLAAGYNRTRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHFEV 441

Query: 765 IDVLLQYG 772
            ++LL  G
Sbjct: 440 TEMLLXAG 417

 Score = 31.2 bits (69), Expect = 1.7,   Method: Compositional matrix adjust.
 Identities = 23/60 (38%), Positives = 28/60 (46%)
 Frame = -1

Query: 716 GRTALHLACRKGNVVLAQLLIWYGVDVMARDAHGNTALAYARQASSQECIDVLLQYGCPD 775
           G   LH AC  G+  + QLL+ +G D  ARD    T L  A      +   VLLQ  C D
Sbjct: 947 GLIPLHNACSFGHAEVVQLLLRHGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQQ-CAD 771
>00540
          Length = 3034

 Score = 37.4 bits (85), Expect = 0.022,   Method: Compositional matrix adjust.
 Identities = 24/87 (27%), Positives = 42/87 (48%)
 Frame = -2

Query: 686  ATAEEDLRTVILLLAHGSRDEVNETCGEGDGRTALHLACRKGNVVLAQLLIWYGVDVMAR 745
            A  +  L  V  L+ H +  E+  +     G T L +AC +G++ + + L++ G  V  R
Sbjct: 2949 ACYDGHLEVVQFLVEHKAEIEIANS----HGHTCLMIACYRGHLDVVEYLLYLGAQVNRR 2782

Query: 746  DAHGNTALAYARQASSQECIDVLLQYG 772
               GNTAL  + ++     + +LL  G
Sbjct: 2781 SVKGNTALHDSAESGKLSIMKLLLSKG 2701
>13745
          Length = 1045

 Score = 36.2 bits (82), Expect = 0.054,   Method: Compositional matrix adjust.
 Identities = 26/109 (23%), Positives = 48/109 (44%), Gaps = 3/109 (2%)
 Frame = +2

Query: 133 FAMWVDAVIFVFSLEDEISFQTVYHYYSRM---ANYRNTSEIPLVLVGTQDAISSTNPRV 189
           F    D  + V+ +    SF+ +  +       A+ R+    P V++G +  + +   R 
Sbjct: 32  FYRGADCCVLVYDVTAPNSFKNLDSWRDEFLIQASPRDPEHFPFVVLGNKVDLDN---RQ 202

Query: 190 IDDVRARKLSNDLKRCTYYETCATYGLNVERVFQDVAQKIVATRKKQQL 238
           +   RA++         YYET A  G+NVE  FQ +A+  +    + +L
Sbjct: 203 VSTRRAQQWCQSKNDIPYYETSAKEGINVEMAFQTIAKNALEQETEAEL 349
>02114
          Length = 1072

 Score = 35.8 bits (81), Expect = 0.075,   Method: Compositional matrix adjust.
 Identities = 19/57 (33%), Positives = 30/57 (52%)
 Frame = +1

Query: 716 GRTALHLACRKGNVVLAQLLIWYGVDVMARDAHGNTALAYARQASSQECIDVLLQYG 772
           G T LHLAC  G+    Q L+  GVDV + D    T++  +       C+ +L+++G
Sbjct: 301 GSTPLHLACAHGHSFCVQTLLRCGVDVNSVDKTSWTSVHVSSYHGRLGCLQMLIKWG 471
>19166
          Length = 447

 Score = 35.0 bits (79), Expect = 0.13,   Method: Compositional matrix adjust.
 Identities = 19/62 (30%), Positives = 31/62 (50%), Gaps = 1/62 (1%)
 Frame = +1

Query: 715 DGRTALHLACRKGNVVLAQLLIWYGVDVMARDAHGNTALAYARQASSQECIDVLLQYGC- 773
           +G T LH+AC+K  + + +LL+ YG  + A    G T L  +        +  L+Q+   
Sbjct: 55  NGFTPLHIACKKNRIKVVELLLKYGASIDATTESGLTPLHVSSFMGHMNIVIYLIQHNAY 234

Query: 774 PD 775
           PD
Sbjct: 235 PD 240
>11295
          Length = 1179

 Score = 34.7 bits (78), Expect = 0.14,   Method: Compositional matrix adjust.
 Identities = 26/73 (35%), Positives = 35/73 (47%)
 Frame = +1

Query: 697 LLLAHGSRDEVNETCGEGDGRTALHLACRKGNVVLAQLLIWYGVDVMARDAHGNTALAYA 756
           LLL   + D +       D  TALH+AC   +  +A LL+ YG   MA D  G+T L  A
Sbjct: 118 LLLDGWNGDGIAVNATSNDHVTALHIACCLDDREMASLLLKYGAYAMALDVIGHTPLHVA 297

Query: 757 RQASSQECIDVLL 769
               S+    +LL
Sbjct: 298 CWCGSEGVTRLLL 336
>20036
          Length = 1849

 Score = 33.9 bits (76), Expect = 0.25,   Method: Compositional matrix adjust.
 Identities = 20/59 (33%), Positives = 30/59 (50%)
 Frame = +3

Query: 711  CGEGDGRTALHLACRKGNVVLAQLLIWYGVDVMARDAHGNTALAYARQASSQECIDVLL 769
            C E  G+TAL LA  +    + +LL+  G D   +D  G+TAL  A +      + +LL
Sbjct: 1086 CAEQTGQTALMLATSQCRTDMVELLLETGADCNQQDFDGSTALMCACEHGHTAIVQLLL 1262
>09204
          Length = 1051

 Score = 33.5 bits (75), Expect = 0.34,   Method: Compositional matrix adjust.
 Identities = 25/97 (25%), Positives = 45/97 (46%), Gaps = 2/97 (2%)
 Frame = -3

Query: 139  AVIFVFSLEDEISFQTVYHYYSRMANYRNTSEIPLVLVGTQDAISSTNP--RVIDDVRAR 196
            A I  F L D+ SF  +  +   +  +    E  L + GT+  +   +P  R +    A+
Sbjct: 1007 AAILCFDLTDKSSFDRIRFWIGELRQHEE--ECKLYICGTKFDLVHDDPERRAVPRSVAK 834

Query: 197  KLSNDLKRCTYYETCATYGLNVERVFQDVAQKIVATR 233
             L++D      YET +  G N+E++F  +A+  +  R
Sbjct: 833  ALADDCM-AEIYETSSMTGDNIEKLFTKIAEDYMKER 726
>32770
          Length = 387

 Score = 33.1 bits (74), Expect = 0.51,   Method: Composition-based stats.
 Identities = 22/69 (31%), Positives = 35/69 (50%), Gaps = 4/69 (5%)
 Frame = +2

Query: 172 PLVLVGTQ-DAISSTNPRVIDDV---RARKLSNDLKRCTYYETCATYGLNVERVFQDVAQ 227
           P +LVGTQ D    + P   D V   + +KL+  +    Y+E  A  G  ++RVF+ V  
Sbjct: 32  PFILVGTQADLRHHSQPASKDMVPAHKGKKLARKVGALGYFECSALIGSGLDRVFRQVVT 211

Query: 228 KIVATRKKQ 236
             V  +K++
Sbjct: 212 CAVHPQKRE 238
>20884
          Length = 712

 Score = 32.7 bits (73), Expect = 0.61,   Method: Compositional matrix adjust.
 Identities = 18/51 (35%), Positives = 27/51 (52%)
 Frame = +1

Query: 686 ATAEEDLRTVILLLAHGSRDEVNETCGEGDGRTALHLACRKGNVVLAQLLI 736
           A A   +  V  L+  G+  E  + CG     TALH+ACR+G   + +LL+
Sbjct: 319 AVATRQMWVVRRLMVAGAAMEAPDYCG----NTALHIACREGMTEMVKLLL 459
>16561
          Length = 2029

 Score = 32.0 bits (71), Expect = 0.93,   Method: Compositional matrix adjust.
 Identities = 20/59 (33%), Positives = 28/59 (47%)
 Frame = -3

Query: 715  DGRTALHLACRKGNVVLAQLLIWYGVDVMARDAHGNTALAYARQASSQECIDVLLQYGC 773
            DG TALH +       + QLL+  G  + A +  G + L  A      +C+ VLL  GC
Sbjct: 2015 DGDTALHYSAFGNQPDVLQLLLSKGAKINALNNGGCSTLHVAVNKQHIKCVHVLLNXGC 1839

 Score = 32.0 bits (71), Expect = 0.99,   Method: Compositional matrix adjust.
 Identities = 22/67 (32%), Positives = 33/67 (49%), Gaps = 3/67 (4%)
 Frame = -3

Query: 716  GRTALHLACRKGNVVLAQLLIWYGVDVMARDAHGNTALAYA---RQASSQECIDVLLQYG 772
            G + LH+A  K ++    +L+  G DV  +DA+G+TAL  A   R   S   + + L   
Sbjct: 1913 GCSTLHVAVNKQHIKCVHVLLNXGCDVNXQDAYGDTALHDAIGKRAVKSLTSLSITLALI 1734

Query: 773  CPDERFV 779
             P E  V
Sbjct: 1733 SPSETSV 1713
>13358
          Length = 775

 Score = 32.0 bits (71), Expect = 0.97,   Method: Compositional matrix adjust.
 Identities = 28/104 (26%), Positives = 49/104 (47%), Gaps = 13/104 (12%)
 Frame = -2

Query: 682 QLLRATAEEDLRTV--ILLLAHGSRDEVNETCGE----GDGRTALHLACRKGNV----VL 731
           Q+ +A    D+ T+  +L   H     +N    +    GDG+  LH A  +G+     +L
Sbjct: 627 QVHQAVESGDVETLRQLLYFRHNEPHGLNPCLADCRKPGDGQPLLHKAALRGSYEMLELL 448

Query: 732 AQLLIWYGVDVM--ARDAHGNTALAYAR-QASSQECIDVLLQYG 772
           A+ L++     +   RD H  T L YA  Q   ++ +++L+ YG
Sbjct: 447 AETLVYQRKQRLDSIRDQHFRTCLHYAYGQEHGKQLVNLLMDYG 316
>00552
          Length = 455

 Score = 32.0 bits (71), Expect = 1.1,   Method: Composition-based stats.
 Identities = 22/71 (30%), Positives = 40/71 (56%), Gaps = 10/71 (14%)
 Frame = -1

Query: 72  LKVGIVGNLASGKSALVHRYLTGTY-VQEESPEGGRF-KKEIVVDGQSYLL--------L 121
           LKV ++G+   GKS+L++R+++  +  Q     G  F  K++VVDG+++ +        L
Sbjct: 443 LKVVLLGDGGVGKSSLMNRFVSNKFDAQSFHTIGVEFLTKDVVVDGETFTMQKPARLAQL 264

Query: 122 IRDEGGPPEAQ 132
           +R +   PE Q
Sbjct: 263 VRRQLRNPEVQ 231
>25470
          Length = 400

 Score = 32.0 bits (71), Expect = 1.1,   Method: Composition-based stats.
 Identities = 23/63 (36%), Positives = 30/63 (47%), Gaps = 1/63 (1%)
 Frame = -3

Query: 716 GRTALHLACRKGNVVLAQLLIWYGVDVMARDAHGNTALAYAR-QASSQECIDVLLQYGCP 774
           G   LH AC  G+  + QLL+ +G D  ARD    T L  A  +     CI +L Q   P
Sbjct: 299 GLIPLHNACSFGHAEVVQLLLRHGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQQCADP 120

Query: 775 DER 777
           + R
Sbjct: 119 NIR 111
>27108
          Length = 449

 Score = 30.8 bits (68), Expect = 2.5,   Method: Composition-based stats.
 Identities = 25/68 (36%), Positives = 36/68 (52%), Gaps = 1/68 (1%)
 Frame = -3

Query: 705 DEVNETCGEGDGRTALHLACRKGNV-VLAQLLIWYGVDVMARDAHGNTALAYARQASSQE 763
           D+VN+   +G+  T L  A  K N+ +L  LL   GVD+ ++D  G TAL  A      E
Sbjct: 414 DKVNKKNHKGE--TMLIRAAIKNNLSLLKHLLTVPGVDINSQDYAGWTALHEACNHGHLE 241

Query: 764 CIDVLLQY 771
           C   LL++
Sbjct: 240 CARALLKF 217
>01398
          Length = 1421

 Score = 30.4 bits (67), Expect = 2.6,   Method: Compositional matrix adjust.
 Identities = 18/89 (20%), Positives = 41/89 (46%)
 Frame = -2

Query: 139  AVIFVFSLEDEISFQTVYHYYSRMANYRNTSEIPLVLVGTQDAISSTNPRVIDDVRARKL 198
             VI V+ +    +F+ +  +Y    N+    +   +++G +      + R +     R+ 
Sbjct: 1372 GVIIVYDITKRSTFENLKQWYEEARNHIEPHKAIFLVLGHKS--DREDARQVTAREGRRF 1199

Query: 199  SNDLKRCTYYETCATYGLNVERVFQDVAQ 227
            + ++    ++ET A  G N+E VF  +A+
Sbjct: 1198 A-EMHGLKFFETSAKSGHNIEDVFAQIAK 1115
>02055
          Length = 1740

 Score = 30.0 bits (66), Expect = 3.8,   Method: Compositional matrix adjust.
 Identities = 18/53 (33%), Positives = 26/53 (49%)
 Frame = +3

Query: 718 TALHLACRKGNVVLAQLLIWYGVDVMARDAHGNTALAYARQASSQECIDVLLQ 770
           T LH+ACR        LLI  G  +   DA G T L  A + +    +++LL+
Sbjct: 531 TPLHVACRLRGQQEVALLIQLGARIDVNDATGTTPLQMACKRADPAVVNILLR 689
>09214
          Length = 2116

 Score = 30.0 bits (66), Expect = 4.0,   Method: Compositional matrix adjust.
 Identities = 14/38 (36%), Positives = 21/38 (55%)
 Frame = -3

Query: 715  DGRTALHLACRKGNVVLAQLLIWYGVDVMARDAHGNTA 752
            +GRTALH   ++ +  + Q L+ +G D  A D  G  A
Sbjct: 1613 NGRTALHWGAKRDHQTVVQYLLSHGADKNAVDNDGKIA 1500
>33484
          Length = 436

 Score = 29.6 bits (65), Expect = 4.8,   Method: Compositional matrix adjust.
 Identities = 22/66 (33%), Positives = 31/66 (46%)
 Frame = -2

Query: 685 RATAEEDLRTVILLLAHGSRDEVNETCGEGDGRTALHLACRKGNVVLAQLLIWYGVDVMA 744
           +A +E D  TV  L   GS  +  E     +G + L LAC  G   LAQ+L+    +V  
Sbjct: 255 QALSERDAGTVRKLYESGSVPDTTE-----EGESLLSLACSAGYYELAQVLLAMNANVED 91

Query: 745 RDAHGN 750
           R   G+
Sbjct: 90  RGIKGD 73
>34789
          Length = 1249

 Score = 29.6 bits (65), Expect = 5.6,   Method: Compositional matrix adjust.
 Identities = 22/59 (37%), Positives = 26/59 (44%)
 Frame = +3

Query: 715 DGRTALHLACRKGNVVLAQLLIWYGVDVMARDAHGNTALAYARQASSQECIDVLLQYGC 773
           DG TAL +A   GNV L   L+  G +      HGN  L  A  + S   I   L  GC
Sbjct: 75  DGSTALFMAVYDGNVELVDYLLKNGANPHFSSQHGNF-LHAAVLSQSVPLIQRALDLGC 248
>27067
          Length = 409

 Score = 29.3 bits (64), Expect = 5.7,   Method: Compositional matrix adjust.
 Identities = 20/62 (32%), Positives = 31/62 (50%), Gaps = 1/62 (1%)
 Frame = +1

Query: 716 GRTALHLACRKGNV-VLAQLLIWYGVDVMARDAHGNTALAYARQASSQECIDVLLQYGCP 774
           G +A+H A +  N  +L  LL   G++  A +A   T +  A      EC+ +LL +GC 
Sbjct: 25  GSSAVHEAIKVNNTDILRYLLTVPGLECNAVNASQKTPVMEAASRGRIECLTMLLDHGCN 204

Query: 775 DE 776
            E
Sbjct: 205 TE 210
>14764
          Length = 2105

 Score = 29.3 bits (64), Expect = 6.4,   Method: Compositional matrix adjust.
 Identities = 23/77 (29%), Positives = 35/77 (45%), Gaps = 10/77 (12%)
 Frame = -3

Query: 358 GKSLNKEWKK---KYVTLCDNGVL-TYHPSLHDYMQNVHGKEIDLLRTTVKV------PG 407
            KSLNKEW++    Y  L DN +L + H S      + +G+  D ++           PG
Sbjct: 987 AKSLNKEWQEYDATYRLLTDNALLDSLHWSEKGQQYSDYGRHSDRVKLEKPPPPAHLQPG 808

Query: 408 KRPPRATSACAPISSPK 424
           +RPP        ++ PK
Sbjct: 807 QRPPDLPKVRVSLTEPK 757
>15772
          Length = 1282

 Score = 28.9 bits (63), Expect = 8.3,   Method: Compositional matrix adjust.
 Identities = 16/35 (45%), Positives = 21/35 (60%)
 Frame = -3

Query: 717  RTALHLACRKGNVVLAQLLIWYGVDVMARDAHGNT 751
            +TALH AC+KG V   +LL+ +G    AR   G T
Sbjct: 1175 KTALHWACQKGFVECIRLLLDHGAKGTARTDTGWT 1071
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|56090560|ref|NP_001007574.1| hypothetical protein
LOC215090 [Mus musculus]
         (452 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

02025                                                                 275   2e-74
03120                                                                 266   2e-71
18694                                                                  28   6.7  
>02025
          Length = 861

 Score =  275 bits (704), Expect = 2e-74,   Method: Compositional matrix adjust.
 Identities = 130/252 (51%), Positives = 166/252 (65%)
 Frame = +3

Query: 192 DDNGEPTDDLVPAILDTAHQYNIQVAFHIQPYKGRDDITVHDNIKYIIDTYGSHGAFYRY 251
           DDNGEP D L P +L +AH + ++VAFHI+PYK R   T+  NIKYIIDTYG H   YR 
Sbjct: 3   DDNGEPVDRLFPLLLHSAHTHGVKVAFHIEPYKNRSGETLRKNIKYIIDTYGXHPGLYR- 179

Query: 252 KNSMGKSLPLFYIYDSYLTSPEAWAHLLTQNGPHSIRNTPYDGVFIALLVEESHTHDILA 311
           +++ GK LP++YIYDSY      WA  L  +G HS+R T YDG+F+ L +       +  
Sbjct: 180 RDAGGKQLPVYYIYDSYQIDSSDWAKALKPDGKHSLRGTQYDGIFLGLYLGPDDERKLTT 359

Query: 312 AGFDGMYTYFASNGFSFGSSHQNWKAVKNFCDTNNLMFIPSVGPGYIDTSIRPWNNHNTR 371
           AGFDG YTYFA+N F+ GSS  NW+ + +F   NNL+F+PSVGPGY+DT IRPWN  NTR
Sbjct: 360 AGFDGFYTYFAANRFTKGSSWSNWQNMADFAAKNNLLFVPSVGPGYVDTRIRPWNGENTR 539

Query: 372 NRVNGKYYETALQAALTVRPEIVSITSFNEWHEGTQIEKAVPKTTPTRLYLDYLPHQSSL 431
            R+ GKY   + Q AL    +++S+TSFNEWHEG+Q+E AVPK      Y DYLP     
Sbjct: 540 KRLQGKYLRHSFQTALDAGAKMISVTSFNEWHEGSQVEPAVPKEIEGFKYEDYLPGPPDF 719

Query: 432 YLELTRRWAEHF 443
           YL L R + + F
Sbjct: 720 YLRLLREYVDRF 755
>03120
          Length = 1415

 Score =  266 bits (679), Expect = 2e-71,   Method: Compositional matrix adjust.
 Identities = 126/246 (51%), Positives = 161/246 (65%)
 Frame = +3

Query: 192 DDNGEPTDDLVPAILDTAHQYNIQVAFHIQPYKGRDDITVHDNIKYIIDTYGSHGAFYRY 251
           DDNG+P D L P +L +AH + ++VAFHI+PYK R   T+  NIKYIIDTYG+H   YR 
Sbjct: 3   DDNGDPVDRLFPLLLHSAHTHGVKVAFHIEPYKNRSGETLRKNIKYIIDTYGTHPGLYR- 179

Query: 252 KNSMGKSLPLFYIYDSYLTSPEAWAHLLTQNGPHSIRNTPYDGVFIALLVEESHTHDILA 311
           +++ GK LP++YIYDSY      WA  L  +G HS+R T YDG+F+ L +       +  
Sbjct: 180 RDAGGKQLPVYYIYDSYQIDSSDWAKALKPDGKHSLRGTQYDGIFLGLYLGPDDEXKLTT 359

Query: 312 AGFDGMYTYFASNGFSFGSSHQNWKAVKNFCDTNNLMFIPSVGPGYIDTSIRPWNNHNTR 371
           AGFDG YTYFA+N F  GSS  NW+ + +F   NNL+F+PSVGPGY+D  IRPWN  N R
Sbjct: 360 AGFDGFYTYFAANRFXKGSSWSNWQNMADFAAKNNLLFVPSVGPGYVDXRIRPWNXENXR 539

Query: 372 NRVNGKYYETALQAALTVRPEIVSITSFNEWHEGTQIEKAVPKTTPTRLYLDYLPHQSSL 431
            R+ GKY   + Q AL    +++S+TSFNEWHEG+Q+E AVPK      Y DYLP     
Sbjct: 540 KRLQGKYLRHSFQTALDAGAKMISVTSFNEWHEGSQVEPAVPKEIEGFKYEDYLPGPPDF 719

Query: 432 YLELTR 437
           YL L R
Sbjct: 720 YLRLLR 737
>18694
          Length = 1201

 Score = 28.1 bits (61), Expect = 6.7,   Method: Compositional matrix adjust.
 Identities = 14/43 (32%), Positives = 21/43 (48%)
 Frame = -1

Query: 402 WHEGTQIEKAVPKTTPTRLYLDYLPHQSSLYLELTRRWAEHFI 444
           W E TQ  K + + T +RL+    P Q++  L    RW  H +
Sbjct: 475 WWEDTQTTKPMDRRTRSRLFNSPCPLQATCRLMACDRWVLHHL 347
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|68448547|ref|NP_694817.2| eukaryotic translation
initiation factor 2C, 4 [Mus musculus]
         (861 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

19404                                                                 276   3e-74
06972                                                                 265   4e-71
02516                                                                 113   4e-25
22922                                                                  44   2e-04
01764                                                                  37   0.023
18700                                                                  32   0.94 
34844                                                                  32   1.2  
02771                                                                  29   8.1  
>19404
          Length = 576

 Score =  276 bits (705), Expect = 3e-74,   Method: Compositional matrix adjust.
 Identities = 140/202 (69%), Positives = 158/202 (78%), Gaps = 6/202 (2%)
 Frame = +1

Query: 517 KTPVYAEVKRVGDTLLGMATQCVQVKNVVKTSPQTLSNLCLKMNAKLGGINNVLVPHQRP 576
           KTPVYAEVKRVGD + G+ATQCVQ KNV KT+PQTLSNLCLK+N KLGG+N++L+P  RP
Sbjct: 1   KTPVYAEVKRVGDIMFGLATQCVQSKNVNKTTPQTLSNLCLKINVKLGGVNSILLPSIRP 180

Query: 577 SVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDGHPSRYCATVRVQTSRQEITQELLY 636
           +VF++PVIFLGADVTHPPAGD  KPSIAAVVGSMD HPSRY A VRVQ  R         
Sbjct: 181 AVFREPVIFLGADVTHPPAGDSSKPSIAAVVGSMDAHPSRYAAAVRVQEHR--------- 333

Query: 637 SQEVVQDLTSMARELLIQFYKSTRFKPTRIIYYRGGVSEGQMK-----QVAWPELIAIRK 691
            QEV+ +L +M RELLIQFY+STRFKPTRII+YR GVSEGQ       QV   EL AIR+
Sbjct: 334 -QEVIYELATMVRELLIQFYRSTRFKPTRIIFYRDGVSEGQFHASTYLQVLSHELRAIRE 510

Query: 692 ACISLEEDYRPG-ITYIVVQKR 712
           AC  LE DYRPG  T+IVVQKR
Sbjct: 511 ACTKLEGDYRPGNTTFIVVQKR 576
>06972
          Length = 1038

 Score =  265 bits (678), Expect = 4e-71,   Method: Compositional matrix adjust.
 Identities = 122/158 (77%), Positives = 136/158 (86%)
 Frame = +1

Query: 704 ITYIVVQKRHHTRLFCADKMERVGKSGNVPAGTTVDSTVTHPSEFDFYLCSHAGIQGTSR 763
           IT+IVVQKRHHTRLFCA+K E+ GKSGN+PAGTTVD  +THP+EFDFYLCSH GIQGT R
Sbjct: 4   ITFIVVQKRHHTRLFCAEKKEQSGKSGNIPAGTTVDVGITHPTEFDFYLCSHQGIQGTXR 183

Query: 764 PSHYQVLWDDNCFTADELQLLTYQLCHTYVRCTRSVSIPAPAYYARLVAFRARYHLVDKD 823
           PSHY VLWDDN F +DELQ LTYQLCHTYVRCTRSVSIPAPAYYA LVAFRARYHLV+K+
Sbjct: 184 PSHYHVLWDDNHFDSDELQCLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVEKE 363

Query: 824 HDSAEGSHVSGQSNGRDPQALAKAVQIHHDTQHTMYFA 861
           HDS EGSH SG S  R P A+A+A+ +H DT+  MYFA
Sbjct: 364 HDSGEGSHQSGSSEDRTPGAMARAITVHADTKKVMYFA 477
>02516
          Length = 2764

 Score =  113 bits (282), Expect = 4e-25,   Method: Compositional matrix adjust.
 Identities = 105/418 (25%), Positives = 181/418 (43%), Gaps = 32/418 (7%)
 Frame = +1

Query: 428  DMRGKQFYAGIEIKVWAVACFAPQKQCREDLLKSFTDQLRKISKDAGMPIQGQPCFCKYA 487
            DMRGK+    + ++ W +     QK+   D  K     L K+    GM I   P   +  
Sbjct: 1471 DMRGKKMVLAVPLQRWLLVV---QKR-STDKAKDLAGILAKVGPPMGMNI-APPRMVQID 1635

Query: 488  QGADSVEPMFKHLKMTYVGLQLIVVILPG-KTPVYAEVKRVGDTLLGMATQCVQVKNVVK 546
            Q  +          +     QL+V +L   K   Y  +K+     + +A+Q V  K +  
Sbjct: 1636 QDRNDSYIHALRENIREGETQLVVCVLSNNKKDRYDAIKKYCCIDMPVASQMVTDKTL-- 1809

Query: 547  TSPQTL----SNLCLKMNAKLGGINNVLVPHQRPSVFQQPV-----IFLGADVTHPPAGD 597
            ++ Q L    + + ++MN KLGG+           V+  P+     + +G D  H  A  
Sbjct: 1810 SNKQRLMSVATKIAIQMNCKLGGV-----------VWVCPIPLVNTMIVGIDTYHDSAVR 1956

Query: 598  GKKPSIAAVVGSMDGHPSRYCATVRVQTSRQEITQELLYSQEVVQDLTSMARELLIQFYK 657
            G+  S+  +V +++   SRY +T   Q    E+  +L +S  ++  L +  RE       
Sbjct: 1957 GQ--SVGGIVATVNSDYSRYFSTCTFQMRHLELQDKLYFS--IIACLKAYGRE------- 2103

Query: 658  STRFKPTRIIYYRGGVSEGQMKQVAWPELIAIRKACISLEE--DYRPGITYIVVQKRHHT 715
            +    P +++ +R GV +GQ++ V   E+  +R+A     E  D    + YI+V+KR + 
Sbjct: 2104 NNNKYPDKVVVFRDGVGDGQLQLVYEHEIPQVRRALNKCAERFDMTIKLAYIIVKKRTNA 2283

Query: 716  RLF--------------------CADKMERVGKSGNVPAGTTVDSTVTHPSEFDFYLCSH 755
            R F                          +     N   GT +D+  T P+ FDF+L S 
Sbjct: 2284 RFFQEGVIMESGPGGARGGRGGGGGAGGGQRRGLTNPGPGTIIDNVATKPTWFDFFLISQ 2463

Query: 756  AGIQGTSRPSHYQVLWDDNCFTADELQLLTYQLCHTYVRCTRSVSIPAPAYYARLVAF 813
            +   GT  P+H+ V++D+    ++  Q + Y+LCH Y     ++ +PAP  YA  +AF
Sbjct: 2464 SVRDGTVSPTHFNVIFDELDIKSEYYQRMAYKLCHMYYNWQGTIRVPAPCMYAHKLAF 2637
>22922
          Length = 970

 Score = 44.3 bits (103), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 20/55 (36%), Positives = 33/55 (60%)
 Frame = +2

Query: 759 QGTSRPSHYQVLWDDNCFTADELQLLTYQLCHTYVRCTRSVSIPAPAYYARLVAF 813
           +GT  P+ Y V+ D+    AD+LQ+L+Y++ H Y   + +  +PA   YA  +AF
Sbjct: 569 KGTVSPTSYNVIQDNMGLDADKLQMLSYKMTHLYYNWSGTCRVPAVCQYAHKLAF 733
>01764
          Length = 441

 Score = 37.4 bits (85), Expect = 0.023,   Method: Compositional matrix adjust.
 Identities = 22/84 (26%), Positives = 36/84 (42%)
 Frame = -3

Query: 758 IQGTSRPSHYQVLWDDNCFTADELQLLTYQLCHTYVRCTRSVSIPAPAYYARLVAFRARY 817
           +     P  + V++D+    ++  Q + Y+LCH Y     ++ +PAP  YA  +AF    
Sbjct: 292 VTAQCHPLTFNVIFDELDIKSEYYQRMAYKLCHMYYNWQGTIRVPAPCMYAHKLAF---- 125

Query: 818 HLVDKDHDSAEGSHVSGQSNGRDP 841
                         + GQS  RDP
Sbjct: 124 --------------LVGQSLHRDP 95
>18700
          Length = 1224

 Score = 32.3 bits (72), Expect = 0.94,   Method: Compositional matrix adjust.
 Identities = 17/56 (30%), Positives = 26/56 (46%)
 Frame = -2

Query: 719 CADKMERVGKSGNVPAGTTVDSTVTHPSEFDFYLCSHAGIQGTSRPSHYQVLWDDN 774
           C  + +R G + +      V  T+  P   D  +C H G+Q TS+P H +    DN
Sbjct: 866 CKREEKRRGGTRSSAYLVAVFGTLCKPPRIDCAVCIHNGVQPTSQPQHTENFRLDN 699
>34844
          Length = 901

 Score = 32.0 bits (71), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 13/40 (32%), Positives = 23/40 (57%)
 Frame = -2

Query: 538 CVQVKNVVKTSPQTLSNLCLKMNAKLGGINNVLVPHQRPS 577
           C+  + V++TS    + +C  + A LGG+NNV +    P+
Sbjct: 468 CMNFQRVIRTSLSHFTCICALIFASLGGLNNVYIALSIPA 349
>02771
          Length = 1591

 Score = 28.9 bits (63), Expect = 8.1,   Method: Compositional matrix adjust.
 Identities = 12/24 (50%), Positives = 17/24 (70%)
 Frame = +3

Query: 682 AWPELIAIRKACISLEEDYRPGIT 705
           AWPE+I IR+  +S+  D RP +T
Sbjct: 726 AWPEVIIIRRRMVSMG*DSRPELT 797
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|165377226|ref|NP_035530.2| solute carrier family 2
(facilitated glucose transporter), member 1 [Mus musculus]
         (492 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

13366                                                                 275   4e-74
17824                                                                 137   1e-32
14422                                                                 123   5e-31
37357                                                                  75   8e-22
35238                                                                  58   9e-09
05016                                                                  35   0.065
>13366
          Length = 1953

 Score =  275 bits (702), Expect = 4e-74,   Method: Compositional matrix adjust.
 Identities = 146/354 (41%), Positives = 213/354 (60%), Gaps = 3/354 (0%)
 Frame = +1

Query: 141 PMYVGEVSPTALRGALGTLHQLGIVVGILIAQVFGLDSIMGNADLWPLLLSVIFIPALLQ 200
           P+Y+ E+SP +LRG  GT +QL I  G++IA+V GLDS++G   LWP  L    +P + Q
Sbjct: 4   PLYLSEISPISLRGLCGTFNQLAICFGVVIAEVVGLDSLLGTPTLWPYALGFTIVPVVFQ 183

Query: 201 CILLPFCPESPRFLLINRNEENRAKSVLKKLRGTADVTRDLQEMKEEGRQMMREKKVTIL 260
            + LP CPE+PRFL++  NE++ A+  L  LRGT DV  +L+EM+ E  ++    K ++ 
Sbjct: 184 LMXLPCCPETPRFLMVVHNEDDEAEKGLIWLRGTEDVGEELEEMRRERAELRNSVKFSVK 363

Query: 261 ELFRSPAYRQPILIAVVLQLSQQLSGINAVFYYSTSIFEKAGVQQPV--YATIGSGIVNT 318
           +LFR+P  R P++I++VL ++QQ SGINAV YYST +FE AG+ + V  YAT G+G VN 
Sbjct: 364 DLFRNPELRWPLIISIVLMMAQQFSGINAVIYYSTDVFEGAGLSEKVSQYATAGTGAVNV 543

Query: 319 AFTVVSLFVVERAGRRTLHLIGLAGMAGCAVLMTIALALLERLPWMSYLSIVAIFGFVAF 378
            +T VS  V+++ GRRTL + GL GM    V++T+AL       W+S+L I A+  ++  
Sbjct: 544 CWTFVSAIVIDKVGRRTLMIAGLGGMLIFTVVLTVALVFQNSATWLSFLCIGAVVLYIVA 723

Query: 379 FEVGPGPIPWFIVAELFSQGPRPAAIAVAGFSNWTSNFIVGMCFQYVEQLCGPXXXXXXX 438
           F  GPG IPWF VAELF+QGPR AA++V+   NW SNF VG+ F  +             
Sbjct: 724 FATGPGAIPWFFVAELFAQGPRSAAVSVSVLINWLSNFTVGLVFPELRDAINEYSFVPFA 903

Query: 439 XXXXXXXXXXXXKVPETKGRTFDEIASGFRQ-GGASQSDKTPEELFHPLGADSQ 491
                        VPETKG+  ++I   F+     SQ++    + +  +  D +
Sbjct: 904 AMLLASLLFVIFFVPETKGKRIEDITLLFKAPDEQSQANIQSSQGYRQISEDEE 1065
>17824
          Length = 450

 Score =  137 bits (345), Expect = 1e-32,   Method: Compositional matrix adjust.
 Identities = 63/148 (42%), Positives = 97/148 (65%)
 Frame = -2

Query: 118 SFEMLILGRFIIGVYCGLTTGFVPMYVGEVSPTALRGALGTLHQLGIVVGILIAQVFGLD 177
           S E+L+L R  +G++ GL     P+Y+ E+SP  +RGA+GT HQL I +GIL++Q+ GL 
Sbjct: 446 SPEVLMLSRVFVGLHSGLNISLCPLYLAEISPRKIRGAIGTCHQLAITIGILVSQILGLR 267

Query: 178 SIMGNADLWPLLLSVIFIPALLQCILLPFCPESPRFLLINRNEENRAKSVLKKLRGTADV 237
            ++G   LWPLL +   +P+++  IL+PFCPESPRFLLI + ++  A+  L  LRGT  V
Sbjct: 266 ELLGTETLWPLLFAFNALPSIMCLILMPFCPESPRFLLIKQGKDEEARKALVGLRGTHXV 87

Query: 238 TRDLQEMKEEGRQMMREKKVTILELFRS 265
             +++EM+ E R+ +     T+ +L  S
Sbjct: 86  DEEMEEMRVEARKSVGVTNFTLKQLVTS 3
>14422
          Length = 444

 Score =  123 bits (309), Expect(2) = 5e-31,   Method: Composition-based stats.
 Identities = 61/122 (50%), Positives = 81/122 (66%)
 Frame = -2

Query: 136 TTGFVPMYVGEVSPTALRGALGTLHQLGIVVGILIAQVFGLDSIMGNADLWPLLLSVIFI 195
           T G  PMY+ E+S   +RGALG LHQLG+V G+L++Q  G   ++GN   W +LL + F+
Sbjct: 389 TRGLSPMYLSEISTPDIRGALGVLHQLGVVSGLLLSQALGFPEVLGNTKTWDILLGITFV 210

Query: 196 PALLQCILLPFCPESPRFLLINRNEENRAKSVLKKLRGTADVTRDLQEMKEEGRQMMREK 255
           P +LQ +L   CPESPRFLLI + +E +A+ VL+ LRGT +V  DL EMK E  Q   E 
Sbjct: 209 PCVLQLLLFLLCPESPRFLLITKKQEQQAEKVLQMLRGTDEVHADLDEMKAEALQQDAEP 30

Query: 256 KV 257
           KV
Sbjct: 29  KV 24

 Score = 29.3 bits (64), Expect(2) = 5e-31,   Method: Composition-based stats.
 Identities = 11/23 (47%), Positives = 17/23 (73%)
 Frame = -1

Query: 118 SFEMLILGRFIIGVYCGLTTGFV 140
           ++EM+I+GR ++G  CGL T  V
Sbjct: 444 AYEMIIVGRLLVGFNCGLYTRVV 376
>37357
          Length = 505

 Score = 75.1 bits (183), Expect(3) = 8e-22,   Method: Compositional matrix adjust.
 Identities = 34/63 (53%), Positives = 46/63 (73%)
 Frame = +3

Query: 365 SYLSIVAIFGFVAFFEVGPGPIPWFIVAELFSQGPRPAAIAVAGFSNWTSNFIVGMCFQY 424
           S  SI+    +V FF +GPG IPW IV+ELFSQGPRPAAI+V+   NW +NF+VG  F +
Sbjct: 102 SSWSIIVSLIYVVFFALGPGSIPWLIVSELFSQGPRPAAISVSVLINWVANFVVGYTFPF 281

Query: 425 VEQ 427
           +++
Sbjct: 282 IQK 290

 Score = 38.1 bits (87), Expect(3) = 8e-22,   Method: Compositional matrix adjust.
 Identities = 17/32 (53%), Positives = 24/32 (75%)
 Frame = +2

Query: 332 GRRTLHLIGLAGMAGCAVLMTIALALLERLPW 363
           GRRTLHL+GL GM   ++L+T+ LAL + + W
Sbjct: 5   GRRTLHLVGLGGMFVFSILITVTLALRDEVQW 100

 Score = 28.1 bits (61), Expect(3) = 8e-22,   Method: Compositional matrix adjust.
 Identities = 10/17 (58%), Positives = 15/17 (88%)
 Frame = +1

Query: 452 VPETKGRTFDEIASGFR 468
           +PETKGRT +EI++ +R
Sbjct: 364 LPETKGRTIEEISTAWR 414
>35238
          Length = 898

 Score = 57.8 bits (138), Expect = 9e-09,   Method: Compositional matrix adjust.
 Identities = 37/106 (34%), Positives = 54/106 (50%), Gaps = 2/106 (1%)
 Frame = +2

Query: 261 ELFRSPAYRQPILIAVVLQLSQQLSGINAVFYYSTSIFEKAGVQ--QPVYATIGSGIVNT 318
           ++ R+P  R+ + +   LQL QQLSGIN V YYS +I ++AG    Q ++       VN 
Sbjct: 14  QMLRTPHVRRALFVGCGLQLFQQLSGINTVIYYSATILKEAGFHATQAIWLVCIPFAVNF 193

Query: 319 AFTVVSLFVVERAGRRTLHLIGLAGMAGCAVLMTIALALLERLPWM 364
             T + +  VER GRR L +    G       + IAL +L    W+
Sbjct: 194 LATFIGIAAVERLGRRALLVCSFIG-------IIIALVVLSTGFWL 310

 Score = 40.0 bits (92), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 29/102 (28%), Positives = 42/102 (41%), Gaps = 1/102 (0%)
 Frame = +2

Query: 363 WMSYLSIVAIFGFVAFFEVGPGPIPWFIVAELFSQGPRPAAIAVAGFSNWTSNFIVGMCF 422
           WM+ L +     FV  F  G GP+PW I +E++    R   +A+A   NW  N  V   F
Sbjct: 602 WMAVLGLAL---FVLSFAPGLGPMPWTINSEIYPMWARGTGVALATMFNWLFNLAVSFTF 772

Query: 423 -QYVEQLCGPXXXXXXXXXXXXXXXXXXXKVPETKGRTFDEI 463
              +E +                       VPETK +T +E+
Sbjct: 773 LTLLETITTYGTFFLFTGVSFLGLLFTVMFVPETKNKTLEEM 898
>05016
          Length = 1381

 Score = 35.0 bits (79), Expect = 0.065,   Method: Compositional matrix adjust.
 Identities = 21/63 (33%), Positives = 31/63 (49%), Gaps = 3/63 (4%)
 Frame = +1

Query: 368 SIVAIFG---FVAFFEVGPGPIPWFIVAELFSQGPRPAAIAVAGFSNWTSNFIVGMCFQY 424
           S +A FG   FV  F  G  P+PW I +E++    R    ++A    W+SN I+   F  
Sbjct: 466 SWIAAFGVALFVFLFSPGMAPMPWTINSEIYPLWARGTCSSLAVTVCWSSNLIISFTFLS 645

Query: 425 VEQ 427
           V +
Sbjct: 646 VTE 654
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|149261084|ref|XP_125901.8| PREDICTED: TBP-interacting
protein isoform 1 [Mus musculus]
         (1438 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

19390                                                                 275   6e-74
22141                                                                  39   0.011
06072                                                                  34   0.53 
>19390
          Length = 542

 Score =  275 bits (704), Expect = 6e-74,   Method: Compositional matrix adjust.
 Identities = 136/179 (75%), Positives = 152/179 (84%), Gaps = 5/179 (2%)
 Frame = +2

Query: 1086 YALGSISVGNLPEYLPFVLQEITSQPKRQYLLLHSLKEIIS--SASVAG---LKPYVENI 1140
            YALG+ISVGNLP++LPFVLQEI +QPKRQYLLLHSLKEIIS  S+S  G   LK Y+  I
Sbjct: 2    YALGNISVGNLPKFLPFVLQEIENQPKRQYLLLHSLKEIISCESSSQTGVEILKSYINTI 181

Query: 1141 WALLLKHCECAEEGTRNVVAECLGKLTLIDPETLLPRLKGYLISGSSYARSSVVTAVKFT 1200
            W +L  +CEC EEGTRNVVAECLGKLTLIDP+TLL  L+ +L   S   RS+VVTAVKFT
Sbjct: 182  WTMLFHNCECPEEGTRNVVAECLGKLTLIDPDTLLGNLQQHLSDESPLTRSTVVTAVKFT 361

Query: 1201 ISDHPQPIDPLLKNCIGDFLKTLEDPDLNVRRVALVTFNSAAHNKPSLIRDLLDSVLPH 1259
            ISD PQ +DP+LK CIGDFLKTL+DPDLNVRRVALVTFNSAAHNKPSLIRD+LDSVLPH
Sbjct: 362  ISDQPQAVDPMLKTCIGDFLKTLQDPDLNVRRVALVTFNSAAHNKPSLIRDMLDSVLPH 538
>22141
          Length = 453

 Score = 39.3 bits (90), Expect = 0.011,   Method: Composition-based stats.
 Identities = 20/41 (48%), Positives = 28/41 (68%)
 Frame = +2

Query: 897 MIDAVLDELPPLISESDMHVSQMAISFLTTLAKVYPSSLSK 937
           MI+ ++ E+PPLISE+D+HVSQ+ I    +L    PS  SK
Sbjct: 2   MINDMMKEMPPLISENDLHVSQV-ICIARSLLHRVPSHFSK 121
>06072
          Length = 1397

 Score = 33.9 bits (76), Expect = 0.53,   Method: Compositional matrix adjust.
 Identities = 21/54 (38%), Positives = 30/54 (55%)
 Frame = +1

Query: 1063 LELKSVILEAFSSPSEEVKSAASYALGSISVGNLPEYLPFVLQEITSQPKRQYL 1116
            LEL  + +   SS  E+V+  A +ALG+I+ G+ PE   +VL E    P  Q L
Sbjct: 409  LELSPIFVRLLSSEVEDVQEQAVWALGNIA-GDSPECREYVLNENILVPLLQLL 567
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31542143|ref|NP_058082.2| ras homolog gene family,
member A [Mus musculus]
         (193 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

19006                                                                 272   8e-74
10708                                                                 156   6e-63
11728                                                                 205   7e-54
19656                                                                 157   3e-39
31291                                                                 144   2e-35
17872                                                                 129   7e-31
07580                                                                  70   6e-13
34468                                                                  69   1e-12
08428                                                                  69   2e-12
11257                                                                  67   4e-12
26083                                                                  66   8e-12
14456                                                                  65   1e-11
07465                                                                  64   3e-11
17511                                                                  64   3e-11
00858                                                                  63   6e-11
09700                                                                  63   7e-11
26536                                                                  62   2e-10
33374                                                                  60   6e-10
01972                                                                  53   7e-10
27191                                                                  59   2e-09
32770                                                                  54   5e-08
13750                                                                  53   8e-08
33794                                                                  52   2e-07
34359                                                                  52   2e-07
35581                                                                  49   1e-06
33380                                                                  49   2e-06
13901                                                                  47   5e-06
00552                                                                  43   9e-05
05468                                                                  41   3e-04
36482                                                                  38   0.003
08153                                                                  37   0.004
11378                                                                  35   0.023
18509                                                                  35   0.028
01095                                                                  34   0.040
09827                                                                  33   0.050
28321                                                                  33   0.059
14775                                                                  33   0.060
06994                                                                  32   0.14 
36757                                                                  32   0.20 
12443                                                                  29   1.1  
19819                                                                  27   5.7  
34597                                                                  26   8.0  
>19006
          Length = 568

 Score =  272 bits (695), Expect = 8e-74,   Method: Compositional matrix adjust.
 Identities = 128/136 (94%), Positives = 134/136 (98%)
 Frame = -2

Query: 5   RKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQE 64
           ++KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVD KQVELALWDTAGQE
Sbjct: 438 KEKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDSKQVELALWDTAGQE 259

Query: 65  DYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRND 124
           DYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEV+HFCPNVPIILVGNKKDLRND
Sbjct: 258 DYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVRHFCPNVPIILVGNKKDLRND 79

Query: 125 EHTRRELAKMKQEPVK 140
           E+T+REL KMKQEPV+
Sbjct: 78  ENTKRELMKMKQEPVR 31
>10708
          Length = 2775

 Score =  156 bits (394), Expect(2) = 6e-63,   Method: Compositional matrix adjust.
 Identities = 72/97 (74%), Positives = 87/97 (89%)
 Frame = -3

Query: 97   EKWTPEVKHFCPNVPIILVGNKKDLRNDEHTRRELAKMKQEPVKPEEGRDMANRIGAFGY 156
            +KWTPEV+HFCPNVPIILVGNKKDLRNDE+T+REL KMKQEPV+ +EGR M+ +I A+ Y
Sbjct: 2590 KKWTPEVRHFCPNVPIILVGNKKDLRNDENTKRELMKMKQEPVRLDEGRAMSEKINAYSY 2411

Query: 157  MECSAKTKDGVREVFEMATRAALQARRGKKKSGCLIL 193
            +ECSAKTK+GVREVFE ATRAALQ ++ KKK GC++L
Sbjct: 2410 LECSAKTKEGVREVFETATRAALQTKK-KKKGGCIVL 2303

 Score =  101 bits (252), Expect(2) = 6e-63,   Method: Compositional matrix adjust.
 Identities = 47/48 (97%), Positives = 48/48 (100%)
 Frame = -2

Query: 51   KQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEK 98
            +QVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEK
Sbjct: 2729 QQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEK 2586
>11728
          Length = 635

 Score =  205 bits (522), Expect = 7e-54,   Method: Compositional matrix adjust.
 Identities = 99/167 (59%), Positives = 119/167 (71%)
 Frame = -1

Query: 1   MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDT 60
           M AI  K V+VGDGA GKTCLLI ++ + FP  Y+PTVF+NY A++ VD K + L LWDT
Sbjct: 497 MQAI--KCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDSKPINLGLWDT 324

Query: 61  AGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKD 120
           AGQEDYDRLRPLSYP TDV L+CFS+ SP S EN+  KW PEV H CPN PIILVG K D
Sbjct: 323 AGQEDYDRLRPLSYPQTDVFLICFSLISPASFENVKAKWYPEVSHHCPNTPIILVGTKLD 144

Query: 121 LRNDEHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGV 167
           LR D+ T  +L + K  P+   +G  MA  IGA  Y+ECSA T+ G+
Sbjct: 143 LREDKETIEKLKEKKLAPITYPQGLAMAKDIGAGKYLECSALTQKGL 3
>19656
          Length = 428

 Score =  157 bits (396), Expect = 3e-39,   Method: Compositional matrix adjust.
 Identities = 71/108 (65%), Positives = 82/108 (75%)
 Frame = +3

Query: 1   MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDT 60
           MA    K V+VGDGA GKTCLLI ++ + FP  Y+PTVF+NY A++ VDG+ V L LWDT
Sbjct: 99  MAMQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGRPVNLGLWDT 278

Query: 61  AGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCP 108
           AGQEDYDRLRPLSYP TDV L+CFS+ SP S ENI  KW PEV H CP
Sbjct: 279 AGQEDYDRLRPLSYPQTDVFLLCFSVASPASFENIRAKWYPEVNHHCP 422
>31291
          Length = 446

 Score =  144 bits (364), Expect = 2e-35,   Method: Compositional matrix adjust.
 Identities = 68/142 (47%), Positives = 94/142 (66%), Gaps = 3/142 (2%)
 Frame = -1

Query: 55  LALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIIL 114
           L LWDTAGQEDYDRLRPL+YP+TDV ++ FS+ S  S++N+  KW PE++H  P+VPI+L
Sbjct: 446 LQLWDTAGQEDYDRLRPLAYPNTDVFMLXFSLMSEASMKNVKVKWYPEIRHHDPHVPIVL 267

Query: 115 VGNKKDLRNDEHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGVREVFEMA 174
           VG K DLR D+   R+L   +Q+PV   +G D+A  I A  Y ECS+KT++ ++  FE  
Sbjct: 266 VGTKLDLRQDKEAVRKLRSSRQDPVSSNQGNDLAKAIKAKRYFECSSKTQENLKTAFEET 87

Query: 175 TRAALQ---ARRGKKKSGCLIL 193
            R AL        + K  C++L
Sbjct: 86  VRVALNMDGQNNKRPKPKCVLL 21
>17872
          Length = 700

 Score =  129 bits (324), Expect = 7e-31,   Method: Compositional matrix adjust.
 Identities = 58/118 (49%), Positives = 83/118 (70%)
 Frame = -1

Query: 63  QEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLR 122
           Q+D+D LRPL YP+T+V L+CFS+ SP S  N+ EKW PE+++ CP  P+++VG + DLR
Sbjct: 700 QDDFDSLRPLCYPETNVFLLCFSVVSPTSFHNVMEKWVPELRYHCPGAPLVVVGTQSDLR 521

Query: 123 NDEHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGVREVFEMATRAALQ 180
           ND     ELAK K++PV  EE   MA+++GA  Y+ECSA T+  ++EVF+    A+L 
Sbjct: 520 NDVKVLIELAKYKEKPVSEEEAVKMADQLGA-QYVECSALTQKNLKEVFDTGILASLN 350
>07580
          Length = 921

 Score = 70.1 bits (170), Expect = 6e-13,   Method: Compositional matrix adjust.
 Identities = 53/180 (29%), Positives = 90/180 (50%), Gaps = 8/180 (4%)
 Frame = +3

Query: 22  LIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVIL 81
           L    K  F E Y PT+ ++Y   +EVDG+Q  L + DTAG E +  +R L   +    L
Sbjct: 111 LYSLCKGIFVEKYDPTIEDSYRKQVEVDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFL 290

Query: 82  MCFSIDSPDSLENIPE--KWTPEVKHFCPNVPIILVGNKKDLRNDEHTRRELAKMKQEPV 139
           + +SI +  +  ++ E  +    VK    +VP++LVGNK DL +            +  V
Sbjct: 291 LAYSITAQSTFNDLQELREQILRVKD-TDDVPMLLVGNKCDLED------------ERVV 431

Query: 140 KPEEGRDMANRIGAFGYMECSAKTKDGVREVF-----EMATRAALQA-RRGKKKSGCLIL 193
             ++G+ +A R  +  ++E SAK +  V E+F     ++  ++  Q+ +R K K  C +L
Sbjct: 432 GKDQGQGLA-RSFSCAFLETSAKARINVNEIFMDLVRQINKKSPEQSGKRTKSKKSCTVL 608
>34468
          Length = 1502

 Score = 68.6 bits (166), Expect = 1e-12,   Method: Compositional matrix adjust.
 Identities = 39/119 (32%), Positives = 64/119 (53%), Gaps = 4/119 (3%)
 Frame = +1

Query: 7   KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYV-ADIEVDGKQVELALWDTAGQED 65
           K++++GD   GKTCL   F   +FP+    T+  ++    I+VD + ++L LWDTAGQE 
Sbjct: 499 KIIVIGDSNVGKTCLTYRFCLGKFPDKTEATIGVDFREKSIQVDSEHLKLQLWDTAGQER 678

Query: 66  YDR-LRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEV--KHFCPNVPIILVGNKKDL 121
           + + +    Y +   ++  + +    S EN+P  W  E    +    +P ILVGNK D+
Sbjct: 679 FRKSMVQHYYRNVHAVVFVYDMTKMSSFENMP-AWIEECDRHNLTKYIPRILVGNKCDV 852
>08428
          Length = 1109

 Score = 68.6 bits (166), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 46/167 (27%), Positives = 81/167 (48%), Gaps = 2/167 (1%)
 Frame = -3

Query: 7    KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVA-DIEVDGKQVELALWDTAGQED 65
            K+ ++GD   GK+ +++ F    +      T+  ++++  + VDG      +WDTAGQE 
Sbjct: 1065 KVCLLGDSGVGKSSIVLRFVTGSYRPSQESTIGASFMSKSLVVDGAGYRFQIWDTAGQEK 886

Query: 66   YDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFC-PNVPIILVGNKKDLRND 124
            +  L P+ Y      ++ + +  P + +++ + W  E++ F  PN+ + + GNK DL   
Sbjct: 885  FRALAPMYYRGAAAAVIVYDVTRPRTFKSV-KSWIQELRSFGPPNIVLAIAGNKCDL--- 718

Query: 125  EHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGVREVF 171
            E  R  + K  QE          A+ I A  + E SA T   V E+F
Sbjct: 717  EELREVVEKDAQE---------YASSISAI-FGETSAMTAVNVEEMF 607
>11257
          Length = 1102

 Score = 67.4 bits (163), Expect = 4e-12,   Method: Compositional matrix adjust.
 Identities = 42/137 (30%), Positives = 64/137 (46%), Gaps = 5/137 (3%)
 Frame = -2

Query: 45   DIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVK 104
            D+ VDG+   + +WDTAGQE Y  LR   Y  TD  L+ FS+D+  SL+++ + W  E  
Sbjct: 1050 DVVVDGETFTMQIWDTAGQERYKSLRTPFYRGTDCCLLTFSVDNLKSLQSLSD-WYDEFV 874

Query: 105  HFC-----PNVPIILVGNKKDLRNDEHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMEC 159
            ++       + P +++GNK D+   E             V  E+  +     G   Y E 
Sbjct: 873  NYADIQDSASFPFVIIGNKADIEERE-------------VSSEDAYNWCRTHGNLPYFET 733

Query: 160  SAKTKDGVREVFEMATR 176
            SAK    V++ F    R
Sbjct: 732  SAKDSLNVQQAFLAVVR 682
>26083
          Length = 432

 Score = 66.2 bits (160), Expect = 8e-12,   Method: Compositional matrix adjust.
 Identities = 38/114 (33%), Positives = 63/114 (55%), Gaps = 2/114 (1%)
 Frame = +1

Query: 7   KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVA-DIEVDGKQVELALWDTAGQED 65
           KLV +G+ + GKT L+  F  D F   Y  T+  ++++  + ++ + + L LWDTAGQE 
Sbjct: 82  KLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTIRLQLWDTAGQER 261

Query: 66  YDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVK-HFCPNVPIILVGNK 118
           +  L P    D+ V ++ + I + +S      KW  +V+     +V I+LVGNK
Sbjct: 262 FRSLIPSYIRDSSVAVVVYDITNANSFHQ-TSKWIDDVRTERGSDVIIMLVGNK 420
>14456
          Length = 1867

 Score = 65.5 bits (158), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 47/169 (27%), Positives = 71/169 (42%), Gaps = 6/169 (3%)
 Frame = -1

Query: 14   GACGKTCLLIVFSKDQFPEVYVPTVFENYV-ADIEVDGKQVELALWDTAGQEDYDRLRPL 72
            G  GK+ L+  F  ++F      T+   ++  D+ VD +   + +WDTAGQE +  LR  
Sbjct: 1114 GGVGKSSLMNRFVSNKFDAQSFHTIGVEFLNKDVVVDDETYTMQIWDTAGQERFKSLRTP 935

Query: 73   SYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCP-----NVPIILVGNKKDLRNDEHT 127
             Y   D  L+ FS+DS  S  N+   W  E  ++         P +++GNK D+   +  
Sbjct: 934  FYRGADCCLLTFSVDSMQSFRNLS-MWRKEFLYYADIQDGVTFPFVVLGNKIDVEGRQ-- 764

Query: 128  RRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGVREVFEMATR 176
                       V  EE R          Y E SAK    V + F  A +
Sbjct: 763  -----------VTNEEARSWCTANSNAPYFETSAKDATNVEKAFLAAVQ 650
>07465
          Length = 1103

 Score = 64.3 bits (155), Expect = 3e-11,   Method: Compositional matrix adjust.
 Identities = 45/154 (29%), Positives = 74/154 (48%), Gaps = 1/154 (0%)
 Frame = +3

Query: 19  TCLLIVFSKDQFPEVYVPTVFENYVA-DIEVDGKQVELALWDTAGQEDYDRLRPLSYPDT 77
           + ++  + K  F + Y  T+  +++   IEV G+ V L LWDTAGQE++D +    Y   
Sbjct: 240 SSMIQRYCKGIFTKDYKKTIGVDFLERQIEVGGEDVRLMLWDTAGQEEFDAITKAYYRGA 419

Query: 78  DVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRNDEHTRRELAKMKQE 137
              ++ FS    DS E + E W  +V+     + +++V NK DL +D             
Sbjct: 420 QACVLAFSTVDRDSFEAL-ETWKRKVEDEVGEIGMVIVQNKIDLIDD------------A 560

Query: 138 PVKPEEGRDMANRIGAFGYMECSAKTKDGVREVF 171
            V+PEE  ++A ++    +   S K    V EVF
Sbjct: 561 VVRPEEAENLAKKL-RLRFYRTSVKENMNVDEVF 659
>17511
          Length = 483

 Score = 63.9 bits (154), Expect = 3e-11,   Method: Compositional matrix adjust.
 Identities = 39/130 (30%), Positives = 69/130 (53%), Gaps = 9/130 (6%)
 Frame = -3

Query: 1   MAAIRK---KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVA-DIEVDGKQVELA 56
           MA+ +K   K++I+GD   GKT L+  +   +F   Y  T+  +++  ++ VD + V + 
Sbjct: 388 MASRKKVLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQ 209

Query: 57  LWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPE-VKHFCP----NVP 111
           +WDTAGQE +  L    Y   D  ++ F +  P++  ++ + W  E +    P    N P
Sbjct: 208 IWDTAGQERFQSLGVAFYRGADCCVLVFDVTMPNTFRSL-DSWRDEFLIQASPRDPENFP 32

Query: 112 IILVGNKKDL 121
            +++GNK DL
Sbjct: 31  FVVIGNKIDL 2
>00858
          Length = 1658

 Score = 63.2 bits (152), Expect = 6e-11,   Method: Compositional matrix adjust.
 Identities = 49/163 (30%), Positives = 78/163 (47%), Gaps = 4/163 (2%)
 Frame = -2

Query: 18   KTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDT 77
            K+ L I   ++ F E Y PT  ++    + +DG+   L + DTAGQE+   +R       
Sbjct: 1552 KSALTIQLXQNHFVEEYDPTXEDSXRKQVVIDGETCLLDILDTAGQEEXSAMRDQCMRTG 1373

Query: 78   DVILMCFSIDSPDSLENIPEKWTPEVKHF--CPNVPIILVGNKKDL--RNDEHTRRELAK 133
            +  L  F++ +  S E+I  ++  ++K       VP++LVGNK DL  RN          
Sbjct: 1372 EGFLCVFAVXNLKSFEDI-NQYREQIKRVKDADEVPMVLVGNKVDLPIRN---------- 1226

Query: 134  MKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGVREVFEMATR 176
                 V+  +G+ MA  +    Y+E SAKT+ GV + F    R
Sbjct: 1225 -----VEQRQGKHMAE-LYHIPYVETSAKTRQGVDDAFYTLVR 1115
>09700
          Length = 1855

 Score = 63.2 bits (152), Expect = 7e-11,   Method: Compositional matrix adjust.
 Identities = 30/73 (41%), Positives = 48/73 (65%)
 Frame = -1

Query: 108  PNVPIILVGNKKDLRNDEHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGV 167
            P  P++LVG + DLRND     ELAK K++PV  ++   +A+++GA  Y+ECSA T+  +
Sbjct: 1822 PRTPLVLVGTQSDLRNDVKVLIELAKYKEKPVSEDDASKLAHQLGA-SYVECSALTQKNL 1646

Query: 168  REVFEMATRAALQ 180
            +E+F+     +LQ
Sbjct: 1645 KEMFDSCILTSLQ 1607
>26536
          Length = 829

 Score = 61.6 bits (148), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 40/129 (31%), Positives = 60/129 (46%), Gaps = 2/129 (1%)
 Frame = +2

Query: 51  KQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPE--KWTPEVKHFCP 108
           ++V     DTAGQE+Y  +R       D  ++ +S+    S +      +W    +    
Sbjct: 122 RRVSWTFLDTAGQEEYSSMREHYTRSGDGFIVVYSVTDVTSFQEAEAVFRWLTRFQD-ET 298

Query: 109 NVPIILVGNKKDLRNDEHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGVR 168
           ++  +L GNK DL +D              V PEEGR MA+R+G   Y E SAKT D V 
Sbjct: 299 SIHAVLCGNKTDLTSD------------RKVTPEEGRKMADRLGML-YFETSAKTGDNVS 439

Query: 169 EVFEMATRA 177
           +V+    R+
Sbjct: 440 QVYHGLLRS 466

 Score = 44.3 bits (103), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 19/45 (42%), Positives = 31/45 (68%)
 Frame = +2

Query: 7   KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGK 51
           K+V++G G  GK+ L I F++D F +VY PT+ ++Y   I+V G+
Sbjct: 491 KIVMLGSGGVGKSSLTIRFTQDTFLDVYDPTIEDSYRKMIQVSGQ 625
>33374
          Length = 489

 Score = 60.1 bits (144), Expect = 6e-10,   Method: Compositional matrix adjust.
 Identities = 36/124 (29%), Positives = 58/124 (46%), Gaps = 1/124 (0%)
 Frame = +1

Query: 48  VDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEV-KHF 106
           +D   V+  +WDTAGQE Y  L P+ Y      ++ + I + D+     + W  E+ +  
Sbjct: 160 LDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNQDTFGR-AKTWVKELQRQA 336

Query: 107 CPNVPIILVGNKKDLRNDEHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDG 166
            PN+ I L GNK DL N     + + + ++     EE         +  +ME SAKT   
Sbjct: 337 SPNIVIALAGNKADLAN-----KRMVEFEEAQAYAEE--------NSLLFMETSAKTAMN 477

Query: 167 VREV 170
           V ++
Sbjct: 478 VNDI 489
>01972
          Length = 2359

 Score = 53.1 bits (126), Expect(2) = 7e-10,   Method: Compositional matrix adjust.
 Identities = 24/72 (33%), Positives = 42/72 (58%)
 Frame = +3

Query: 52  QVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVP 111
           +++  +WDTAGQE +  LR   Y      ++ F + S  + +N+P  W  ++   C N+P
Sbjct: 444 KLKFNVWDTAGQEKFGGLRDGYYIQGQCAVIMFDVTSRVTYKNVPN-WHRDLVRVCENIP 620

Query: 112 IILVGNKKDLRN 123
           I+L GNK D+++
Sbjct: 621 IVLCGNKVDIKD 656

 Score = 26.2 bits (56), Expect(2) = 7e-10,   Method: Compositional matrix adjust.
 Identities = 10/16 (62%), Positives = 12/16 (75%)
 Frame = +1

Query: 7   KLVIVGDGACGKTCLL 22
           KLV+VGDG  GKT  +
Sbjct: 307 KLVLVGDGGVGKTTFV 354
>27191
          Length = 443

 Score = 58.5 bits (140), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 32/103 (31%), Positives = 56/103 (54%), Gaps = 2/103 (1%)
 Frame = +1

Query: 18  KTCLLIVFSKDQFPEVYVPTVFENYVADIE-VDGKQVELALWDTAGQEDYDRLRPLSYPD 76
           KTCL+  F + +F + Y PTV  +Y   I+ V+G  + + +WD +G  +Y  +R   Y  
Sbjct: 1   KTCLIKHFCESKFNQGYQPTVGVDYGFKIQTVNGVDMRVHMWDLSGSNEYLDVRNELYTG 180

Query: 77  TDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPI-ILVGNK 118
           +D I + F + +  S E + + W  E+  F    P+ ++VGN+
Sbjct: 181 SDAIFIVFDVSNTPSFEAL-DSWLREINRFATGSPLNVIVGNR 306
>32770
          Length = 387

 Score = 53.5 bits (127), Expect = 5e-08,   Method: Compositional matrix adjust.
 Identities = 28/83 (33%), Positives = 44/83 (53%)
 Frame = +2

Query: 101 PEVKHFCPNVPIILVGNKKDLRNDEHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECS 160
           PE++ + P  P ILVG + DLR+  H++     M    V   +G+ +A ++GA GY ECS
Sbjct: 2   PELRDYRPGTPFILVGTQADLRH--HSQPASKDM----VPAHKGKKLARKVGALGYFECS 163

Query: 161 AKTKDGVREVFEMATRAALQARR 183
           A    G+  VF      A+  ++
Sbjct: 164 ALIGSGLDRVFRQVVTCAVHPQK 232
>13750
          Length = 503

 Score = 52.8 bits (125), Expect = 8e-08,   Method: Compositional matrix adjust.
 Identities = 41/156 (26%), Positives = 60/156 (38%), Gaps = 2/156 (1%)
 Frame = -2

Query: 18  KTCLLIVFSKDQFPEVYVPT--VFENYVADIEVDGKQVELALWDTAGQEDYDRLRPLSYP 75
           KTCLL  + K  F +  +PT  V  +   +   D   V   LWDT G E Y  L    + 
Sbjct: 502 KTCLLRRYQKGFFMDRTMPTIAVLCSEFNESRTDPLNVRYTLWDTGGAETYRSLWVSHFR 323

Query: 76  DTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRNDEHTRRELAKMK 135
              V L+ + +    S       W   +    P   +I VG+K DL  +           
Sbjct: 322 GAQVALLVYDVTCEWSFLTATTVWRKALMKNIPEAQVIFVGSKTDLEEN----------- 176

Query: 136 QEPVKPEEGRDMANRIGAFGYMECSAKTKDGVREVF 171
              +  E G+  A + G + + E S+ T   V  VF
Sbjct: 175 -RVISTERGQAFATQCG-YTFFETSSVTGKNVDAVF 74
>33794
          Length = 779

 Score = 52.0 bits (123), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 42/139 (30%), Positives = 63/139 (45%), Gaps = 1/139 (0%)
 Frame = -1

Query: 43  VADIEVDGKQVELALWDTAGQEDY-DRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTP 101
              I ++GK+V+L +WDT+GQ  +   +R  S     +IL+ + I +  S + I ++W  
Sbjct: 680 TTTILLEGKRVKLQIWDTSGQGRFCTIIRSYSRGAQGIILV-YDITNKWSFDGI-DRWLK 507

Query: 102 EVKHFCPNVPIILVGNKKDLRNDEHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSA 161
           EV+   P +P +LVGN          R  LA  +Q   K  E     N +  F   E S 
Sbjct: 506 EVEEHAPGIPKVLVGN----------RLHLAYKRQVAAKQAETYASRNNMSCF---EISP 366

Query: 162 KTKDGVREVFEMATRAALQ 180
                +RE F    R AL 
Sbjct: 365 LCDFNIRESFCELARMALH 309
>34359
          Length = 1042

 Score = 51.6 bits (122), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 24/71 (33%), Positives = 40/71 (56%)
 Frame = +3

Query: 53  VELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPI 112
           +   +WDTAGQE +  LR   Y      ++ F + S  + +N+P  W  ++   C N+PI
Sbjct: 195 LRFNVWDTAGQEKFGGLRDGYYIQGTCAIIMFDVTSRVTYKNVPN-WHRDLVRVCENIPI 371

Query: 113 ILVGNKKDLRN 123
           +L GNK D+++
Sbjct: 372 VLCGNKVDIKD 404
>35581
          Length = 364

 Score = 48.9 bits (115), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 28/80 (35%), Positives = 38/80 (47%), Gaps = 2/80 (2%)
 Frame = +2

Query: 7   KLVIVGDGACGKTCLLIVFSKDQFPE--VYVPTVFENYVADIEVDGKQVELALWDTAGQE 64
           K V++GD   GKTCLL   + D+F +  +   T            G    + LWDTAGQE
Sbjct: 50  KCVLLGDAGVGKTCLLNRLATDKFLDSPLTSLTTASLLTTVTLTSGVMASVDLWDTAGQE 229

Query: 65  DYDRLRPLSYPDTDVILMCF 84
            Y  L    Y DT  +L+ +
Sbjct: 230 RYRSLTSSYYRDTKAVLIVY 289
>33380
          Length = 282

 Score = 48.5 bits (114), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 24/75 (32%), Positives = 42/75 (56%), Gaps = 1/75 (1%)
 Frame = +3

Query: 51  KQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFC-PN 109
           K+V+L +WDTAGQE Y  +    Y      ++ + + + +S  N  + W  ++K +   N
Sbjct: 54  KRVKLQIWDTAGQERYRTITTAYYRGAMGFILMYDVTNEESF-NAVQDWCTQIKTYSWDN 230

Query: 110 VPIILVGNKKDLRND 124
             ++LVGNK DL ++
Sbjct: 231 AQVVLVGNKCDLEDE 275
>13901
          Length = 962

 Score = 47.0 bits (110), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 24/90 (26%), Positives = 44/90 (48%), Gaps = 2/90 (2%)
 Frame = -3

Query: 7   KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADI--EVDGKQVELALWDTAGQE 64
           K++I+GD   GKT  +  +  D F   Y  T+  ++   +    D   ++L LWD AGQE
Sbjct: 282 KVIIIGDPTVGKTSFVQRYVNDSFRRDYKMTIGVDFALKVIRWSDKCNIKLQLWDIAGQE 103

Query: 65  DYDRLRPLSYPDTDVILMCFSIDSPDSLEN 94
            +  +  + Y D    ++ F +   ++ +N
Sbjct: 102 RFTSMTRVYYKDAHACIVMFDLTQKNTYQN 13
>00552
          Length = 455

 Score = 42.7 bits (99), Expect = 9e-05,   Method: Compositional matrix adjust.
 Identities = 21/51 (41%), Positives = 31/51 (60%)
 Frame = -3

Query: 56  ALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHF 106
            +WDTAGQE Y  LR   Y  TD  L+ FS+D+  SL+++ + W  E  ++
Sbjct: 150 GIWDTAGQERYKSLRTPFYRGTDCCLLTFSVDNLKSLQSLSD-WYDEFVNY 1
>05468
          Length = 1558

 Score = 41.2 bits (95), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 29/122 (23%), Positives = 55/122 (45%), Gaps = 8/122 (6%)
 Frame = -3

Query: 7    KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTV---FENYVADIEVDGKQVELALWDTAGQ 63
            K++++G+   GKT ++  +    F + Y  T+   F   V + + D   + L LWD AGQ
Sbjct: 1535 KILVIGELGTGKTSIIKRYVHQFFSQHYRATIGVDFALKVLNWDAD-TLIRLQLWDIAGQ 1359

Query: 64   EDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFC-----PNVPIILVGNK 118
            E +  +  + Y +     + F +    + + +  KW  ++           VP +L+ NK
Sbjct: 1358 ERFGNMTRVYYKEAVGAFVVFDVTRASTFDAVT-KWKNDLDSKVQLADGSPVPCVLLANK 1182

Query: 119  KD 120
             D
Sbjct: 1181 CD 1176
>36482
          Length = 686

 Score = 37.7 bits (86), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 44/174 (25%), Positives = 67/174 (38%), Gaps = 7/174 (4%)
 Frame = +2

Query: 21  LLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVI 80
           L + F   +F   Y PT+   Y     ++   V L + DTAGQ  Y      +    D  
Sbjct: 2   LTVRFLTRRFIGEYCPTLESVYKYHTVIEDDDVRLEILDTAGQGTYPWKEGYALW-ADCF 178

Query: 81  LMCFSIDSPDSLENIPE-KWTPEVKHFCPNVPIILVGNKKDLRNDEHTRRELAKMKQEPV 139
           +  +SI+   S E + + K   E      ++  +L  NK DL +D              V
Sbjct: 179 VFVYSINDRQSYEELVQVKRQVESVRKSTSLTAVLAANKTDLLHDRQ------------V 322

Query: 140 KPEEGRDMANRIGAFGYMECSAKTKDGVREVFEM------ATRAALQARRGKKK 187
             +EG D+A  IG   Y E SA     +  +  M        R   Q R G+++
Sbjct: 323 TQKEGEDLAEEIGCRLY-EVSASEGSQMEAITSMFHDLYREFRKHKQQREGRQR 481
>08153
          Length = 1703

 Score = 37.0 bits (84), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 45/174 (25%), Positives = 74/174 (42%), Gaps = 8/174 (4%)
 Frame = +1

Query: 7   KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDY 66
           ++++VG  A GKT +L      +     +PT+  N      V+ K +   +WD  GQ   
Sbjct: 88  RILMVGLDAAGKTTILYKLKLGEIVTT-IPTIGFNVET---VEYKNISFTVWDVGGQ--- 246

Query: 67  DRLRPL---SYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHF----CPNVPIILVGNKK 119
           D++RPL    + +T  ++  F +DS D  E I E      +        +  I++  NK+
Sbjct: 247 DKIRPLWRHYFQNTQGLI--FVVDSNDR-ERINEAKEELARMLNEDDLRDAIILVFANKQ 417

Query: 120 DLRNDEHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECS-AKTKDGVREVFE 172
           DL N        A +            +AN  G   YM+ + A + DG+ E  E
Sbjct: 418 DLPNAYSASEVTAHL-----------GLANLKGRKWYMQATCATSGDGMYEGLE 546
>11378
          Length = 1688

 Score = 34.7 bits (78), Expect = 0.023,   Method: Compositional matrix adjust.
 Identities = 30/115 (26%), Positives = 49/115 (42%), Gaps = 1/115 (0%)
 Frame = +3

Query: 7   KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDY 66
           KLV +G    GKT LL +   D+  + +VPT+   +    E+    +    +D  G    
Sbjct: 327 KLVFLGLDNAGKTTLLHMLKDDKMAQ-HVPTL---HPTSEELSMGGMRFTTFDLGGHRQA 494

Query: 67  DRLRPLSYPDTDVILMCFSIDSPDSL-ENIPEKWTPEVKHFCPNVPIILVGNKKD 120
            R+    +P  D I+    +   + L E   E  +        N PI+++GNK D
Sbjct: 495 RRVWKDYFPAVDGIVFLVDVHDRERLVEAKAELDSLMTDEQVANAPILVLGNKID 659
>18509
          Length = 625

 Score = 34.7 bits (78), Expect = 0.028,   Method: Compositional matrix adjust.
 Identities = 25/69 (36%), Positives = 34/69 (49%), Gaps = 2/69 (2%)
 Frame = -3

Query: 110 VPIILVGNKKDL--RNDEHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGV 167
           VP++LVGNK DL  RN               V+  +G+ MA  +    Y+E SAKT+ GV
Sbjct: 527 VPMVLVGNKVDLPIRN---------------VEQRQGKHMAE-LYHIPYVETSAKTRQGV 396

Query: 168 REVFEMATR 176
            + F    R
Sbjct: 395 DDAFYTLVR 369
>01095
          Length = 1745

 Score = 33.9 bits (76), Expect = 0.040,   Method: Compositional matrix adjust.
 Identities = 23/74 (31%), Positives = 31/74 (41%), Gaps = 1/74 (1%)
 Frame = -1

Query: 99   WTPEV-KHFCPNVPIILVGNKKDLRNDEHTRRELAKMKQEPVKPEEGRDMANRIGAFGYM 157
            W  E+ +   PN+ I L GNK DL N      E A+   E               +  +M
Sbjct: 1697 WVKELQRQASPNIVIALAGNKADLANKRMVEFEEAQAYAEE-------------NSLLFM 1557

Query: 158  ECSAKTKDGVREVF 171
            E SAKT   V ++F
Sbjct: 1556 ETSAKTAMNVNDIF 1515
>09827
          Length = 1201

 Score = 33.5 bits (75), Expect = 0.050,   Method: Compositional matrix adjust.
 Identities = 27/89 (30%), Positives = 46/89 (51%), Gaps = 5/89 (5%)
 Frame = -3

Query: 7    KLVIVGDGACGKTCLLIVFSKDQFPEVY--VPTVFENYVADIEVDGKQVELALWDTAGQE 64
            ++++VG  A GKT +L    K +  E+   +PT+  N      V+ K +   +WD  GQ 
Sbjct: 1109 RILMVGLDAAGKTTILY---KLKLGEIVTTIPTIGFNVET---VEYKNISFTVWDVGGQ- 951

Query: 65   DYDRLRPL---SYPDTDVILMCFSIDSPD 90
              D++RPL    + +T  ++  F +DS D
Sbjct: 950  --DKIRPLWRHYFQNTQGLI--FVVDSND 876
>28321
          Length = 422

 Score = 33.5 bits (75), Expect = 0.059,   Method: Compositional matrix adjust.
 Identities = 15/19 (78%), Positives = 17/19 (89%)
 Frame = +2

Query: 162 KTKDGVREVFEMATRAALQ 180
           + K+GVREVFE ATRAALQ
Sbjct: 32  QXKEGVREVFETATRAALQ 88
>14775
          Length = 380

 Score = 33.5 bits (75), Expect = 0.060,   Method: Compositional matrix adjust.
 Identities = 22/71 (30%), Positives = 31/71 (43%), Gaps = 2/71 (2%)
 Frame = -2

Query: 18  KTCLLIVFSKDQFPEVYVPT--VFENYVADIEVDGKQVELALWDTAGQEDYDRLRPLSYP 75
           KTCLL  + K  F +  +PT  V  +   +   D   V   LWDT G E Y  L    + 
Sbjct: 379 KTCLLRRYQKGFFMDRTMPTIAVLCSEFNESRTDPLNVRYTLWDTGGAETYRSLWVSHFR 200

Query: 76  DTDVILMCFSI 86
              V L+ + +
Sbjct: 199 GAQVALLVYDV 167
>06994
          Length = 429

 Score = 32.0 bits (71), Expect = 0.14,   Method: Compositional matrix adjust.
 Identities = 14/29 (48%), Positives = 20/29 (68%)
 Frame = +1

Query: 34  YVPTVFENYVADIEVDGKQVELALWDTAG 62
           Y PT+ ++Y   +EVDG+Q  L + DTAG
Sbjct: 142 YDPTIEDSYRKQVEVDGQQCMLEILDTAG 228
>36757
          Length = 359

 Score = 31.6 bits (70), Expect = 0.20,   Method: Compositional matrix adjust.
 Identities = 13/24 (54%), Positives = 18/24 (75%)
 Frame = +2

Query: 156 YMECSAKTKDGVREVFEMATRAAL 179
           Y+ECSA T+ G++ VF+ A RA L
Sbjct: 8   YLECSALTQKGLKTVFDEAIRAVL 79
>12443
          Length = 837

 Score = 29.3 bits (64), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 27/107 (25%), Positives = 47/107 (43%), Gaps = 10/107 (9%)
 Frame = -3

Query: 4   IRKKLVIVGDGACGKTCLLIVFSKDQFPEVY-----VPTVFENYVADIEVDGKQV--ELA 56
           +  K+++VG    GKT  +   + +  P  +     + T    +   I+  GK V  ++ 
Sbjct: 586 VNYKVMLVGKTGVGKTSTVAKLTGNDIPLTHNETPGLQTSHLYWPGKIKHLGKTVLFQIQ 407

Query: 57  LWDTAGQ---EDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWT 100
           L+D AG+   + YD + P      D I+  FS     S + IP+  T
Sbjct: 406 LFD-AGETALKRYDHILPACQDGVDGIMFLFSFVDKGSFDEIPQLLT 269
>19819
          Length = 717

 Score = 26.9 bits (58), Expect = 5.7,   Method: Compositional matrix adjust.
 Identities = 16/38 (42%), Positives = 19/38 (50%), Gaps = 1/38 (2%)
 Frame = +2

Query: 36  PTVFENYVADI-EVDGKQVELALWDTAGQEDYDRLRPL 72
           P V  N V+ + E  G Q    LWDTAG E    L+ L
Sbjct: 116 PVVHGNVVSPVPEY*GSQESSILWDTAGTEGVPLLKVL 229
>34597
          Length = 773

 Score = 26.2 bits (56), Expect = 8.0,   Method: Compositional matrix adjust.
 Identities = 25/99 (25%), Positives = 45/99 (45%), Gaps = 1/99 (1%)
 Frame = -2

Query: 91  SLENIPEKWTPEV-KHFCPNVPIILVGNKKDLRNDEHTRRELAKMKQEPVKPEEGRDMAN 149
           S ENI  KW   + +H   +V  +++GNK D+ +    +R ++K + E +  E       
Sbjct: 709 SFENIV-KWLRNIDEHANEDVEKMILGNKCDMTD----KRVVSKERGEAIAREH------ 563

Query: 150 RIGAFGYMECSAKTKDGVREVFEMATRAALQARRGKKKS 188
              +  +ME SAK+   +   F     A L    G++ +
Sbjct: 562 ---SIRFMETSAKSNINIERAFCELAEAILDKTAGRESA 455
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|21728376|ref|NP_075891.1| myosin, light chain 12B,
regulatory [Mus musculus]
         (172 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

20251                                                                 271   1e-73
14594                                                                 108   1e-24
14366                                                                  70   4e-13
26610                                                                  68   2e-12
22063                                                                  53   2e-12
05237                                                                  66   6e-12
18171                                                                  66   7e-12
11425                                                                  57   3e-09
01019                                                                  55   2e-08
38338                                                                  54   3e-08
14945                                                                  53   5e-08
16255                                                                  44   4e-05
19942                                                                  41   2e-04
07385                                                                  40   7e-04
08108                                                                  39   0.001
01773                                                                  37   0.005
01491                                                                  31   0.20 
19912                                                                  31   0.33 
22273                                                                  30   0.38 
37064                                                                  28   1.4  
07678                                                                  27   3.2  
>20251
          Length = 2203

 Score =  271 bits (693), Expect = 1e-73,   Method: Compositional matrix adjust.
 Identities = 132/159 (83%), Positives = 146/159 (91%)
 Frame = +3

Query: 14  RPQRATSNVFAMFDQSQIQEFKEAFNMIDQNRDGFIDKEDLHDMLASLGKNPTDAYLDAM 73
           R QRATSNVFAMFDQSQIQEFKEAFNMIDQNRDGFIDKEDL DMLASLGKNPT+  LD M
Sbjct: 105 RAQRATSNVFAMFDQSQIQEFKEAFNMIDQNRDGFIDKEDLGDMLASLGKNPTEGQLDEM 284

Query: 74  MNEAPGPINFTMFLTMFGEKLNGTDPEDVIRNAFACFDEEATGTIQEDYLRELLTTMGDR 133
           MN APGPINFTMFLTMFG+KLNGTDPEDVI+NAFACFDE+  G IQED LRELLTTMGDR
Sbjct: 285 MNXAPGPINFTMFLTMFGDKLNGTDPEDVIKNAFACFDEDGKGVIQEDRLRELLTTMGDR 464

Query: 134 FTDEEVDELYREAPIDKKGNFNYIEFTRILKHGAKDKDD 172
           FTD+EVDE++R+API K+GNF+Y+EFTRILK+G K+ D+
Sbjct: 465 FTDDEVDEMFRDAPI-KRGNFDYLEFTRILKYGKKENDE 578
>14594
          Length = 1014

 Score =  108 bits (271), Expect = 1e-24,   Method: Compositional matrix adjust.
 Identities = 62/152 (40%), Positives = 88/152 (57%), Gaps = 16/152 (10%)
 Frame = +3

Query: 30  QIQEFKEAFNMIDQNRDGFIDKEDLHDMLASLGKNPTDAYLDAMMNEAP----GPINFTM 85
           Q+ EFKEAF++ D++ DG I   +L  ++ SLG+NPT+  L  M+NE      G I+F  
Sbjct: 435 QVAEFKEAFSLFDKDGDGTITTSELGTVMRSLGQNPTENELQDMINEVDADGNGTIDFEE 614

Query: 86  FLTMFGEKLNGTDPEDVIRNAFACFDEEATGTIQEDYLRELLTTMGDRFTDEEVDELYRE 145
           FL M   K+  TD E+ +R AF  FD++  G I    LR ++T +G++ TDEEVDE+ +E
Sbjct: 615 FLHMMARKMKDTDCEEELREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIKE 794

Query: 146 APIDKKGNFNYIEF------------TRILKH 165
           A +D  G  NY EF            TR+L H
Sbjct: 795 ADLDGDGMVNYEEFVTMMTAK*PSEGTRLLHH 890

 Score = 39.3 bits (90), Expect = 8e-04,   Method: Compositional matrix adjust.
 Identities = 30/100 (30%), Positives = 47/100 (47%), Gaps = 7/100 (7%)
 Frame = +3

Query: 79  GPINFTMF-----LTMFGEKLNGTDPEDV--IRNAFACFDEEATGTIQEDYLRELLTTMG 131
           GPI FT F     L M  E +     E V   + AF+ FD++  GTI    L  ++ ++G
Sbjct: 357 GPI-FTFFVRHSLLIMSQEHIVTLTDEQVAEFKEAFSLFDKDGDGTITTSELGTVMRSLG 533

Query: 132 DRFTDEEVDELYREAPIDKKGNFNYIEFTRILKHGAKDKD 171
              T+ E+ ++  E   D  G  ++ EF  ++    KD D
Sbjct: 534 QNPTENELQDMINEVDADGNGTIDFEEFLHMMARKMKDTD 653
>14366
          Length = 499

 Score = 70.5 bits (171), Expect = 4e-13,   Method: Compositional matrix adjust.
 Identities = 42/143 (29%), Positives = 76/143 (53%), Gaps = 4/143 (2%)
 Frame = -3

Query: 28  QSQIQEFKEAFNMIDQNRDGFIDKEDLHDMLASLGKNPTDAYLDAMM----NEAPGPINF 83
           Q + +E +EAF +++ + D  I    L  ++ S+G+ PT++ L  +     N     +  
Sbjct: 479 QLRQEELQEAF-IMNCSPDNTIALNKLGIVVRSIGRAPTESQLKTLTMEFENRGKRTLTL 303

Query: 84  TMFLTMFGEKLNGTDPEDVIRNAFACFDEEATGTIQEDYLRELLTTMGDRFTDEEVDELY 143
              + +  +     +  D +R AF  FD+E  G I    LR +LT +G++ +DEEVDE+ 
Sbjct: 302 QEVIAIVTKYEFAPETSDNLREAFRIFDKEGNGMINAAELRHVLTHLGEKLSDEEVDEMI 123

Query: 144 REAPIDKKGNFNYIEFTRILKHG 166
           REA I   G  +Y +F +++++G
Sbjct: 122 READISGDGQVSYNDFVKVMENG 54
>26610
          Length = 455

 Score = 68.2 bits (165), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 43/132 (32%), Positives = 66/132 (50%), Gaps = 4/132 (3%)
 Frame = +3

Query: 36  EAFNMIDQNRDGFIDKEDLHDMLASLGKNPTDAYLDAMMNEA----PGPINFTMFLTMFG 91
           EAF + D + DG I   ++   + SLG   TD+ L  ++++A     G ++   F  +  
Sbjct: 54  EAFELFDTDNDGKIAASEVGTAIRSLGHVVTDSDLRRLLSKAGIEPHGKVDMNRFRQLV- 230

Query: 92  EKLNGTDPEDVIRNAFACFDEEATGTIQEDYLRELLTTMGDRFTDEEVDELYREAPIDKK 151
           + L G +    +  AF   D+E +G +    LR LLT MGDR TDEE + L  E  +D  
Sbjct: 231 QPLQGVNYTKQLDEAFNTIDKEGSGFVMATELRHLLTHMGDRITDEEFNALLEELEVDSN 410

Query: 152 GNFNYIEFTRIL 163
           G     EF ++L
Sbjct: 411 GRVRRKEFVQLL 446

 Score = 33.1 bits (74), Expect = 0.063,   Method: Compositional matrix adjust.
 Identities = 15/45 (33%), Positives = 25/45 (55%)
 Frame = +3

Query: 32  QEFKEAFNMIDQNRDGFIDKEDLHDMLASLGKNPTDAYLDAMMNE 76
           ++  EAFN ID+   GF+   +L  +L  +G   TD   +A++ E
Sbjct: 258 KQLDEAFNTIDKEGSGFVMATELRHLLTHMGDRITDEEFNALLEE 392
>22063
          Length = 688

 Score = 53.1 bits (126), Expect(2) = 2e-12,   Method: Compositional matrix adjust.
 Identities = 31/93 (33%), Positives = 51/93 (54%), Gaps = 4/93 (4%)
 Frame = +3

Query: 28  QSQIQEFKEAFNMIDQNRDGFIDKEDLHDMLASLGKNPTDAYLDAMM----NEAPGPINF 83
           + Q QE +EAF++ D +  G ID ++L   + +LG  P    +  M+     E  G I+F
Sbjct: 159 EEQKQEIREAFDLFDADGSGTIDAKELKVAMRALGFEPKKEEIKKMIAEIDKEGTGTIDF 338

Query: 84  TMFLTMFGEKLNGTDPEDVIRNAFACFDEEATG 116
             FLT+  +K++  D ++ I  AF  FD++ TG
Sbjct: 339 NDFLTIMTQKMSEKDAKEEILKAFRLFDDDETG 437

 Score = 34.7 bits (78), Expect(2) = 2e-12,   Method: Compositional matrix adjust.
 Identities = 20/58 (34%), Positives = 27/58 (46%)
 Frame = +1

Query: 108 ACFDEEATGTIQEDYLRELLTTMGDRFTDEEVDELYREAPIDKKGNFNYIEFTRILKH 165
           AC        I    L+ +   +G+  TDEE+ E+  EA  D  G  N  EF RI+K 
Sbjct: 412 ACLTMMKRAKISFRNLKRVAKELGENLTDEELQEMIDEADRDGDGEINQEEFLRIMKK 585

 Score = 32.0 bits (71), Expect = 0.12,   Method: Compositional matrix adjust.
 Identities = 19/69 (27%), Positives = 33/69 (47%)
 Frame = +3

Query: 103 IRNAFACFDEEATGTIQEDYLRELLTTMGDRFTDEEVDELYREAPIDKKGNFNYIEFTRI 162
           IR AF  FD + +GTI    L+  +  +G     EE+ ++  E   +  G  ++ +F  I
Sbjct: 177 IREAFDLFDADGSGTIDAKELKVAMRALGFEPKKEEIKKMIAEIDKEGTGTIDFNDFLTI 356

Query: 163 LKHGAKDKD 171
           +     +KD
Sbjct: 357 MTQKMSEKD 383
>05237
          Length = 472

 Score = 66.2 bits (160), Expect = 6e-12,   Method: Compositional matrix adjust.
 Identities = 31/67 (46%), Positives = 44/67 (65%)
 Frame = +3

Query: 97  TDPEDVIRNAFACFDEEATGTIQEDYLRELLTTMGDRFTDEEVDELYREAPIDKKGNFNY 156
           TD +D +R AF  FD++  G I    LR ++T +G++ TDEEVDE+ REA ID  G  NY
Sbjct: 15  TDTDDELREAFRVFDKDGNGFISASELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNY 194

Query: 157 IEFTRIL 163
            EF +++
Sbjct: 195 EEFVKMM 215

 Score = 42.7 bits (99), Expect = 7e-05,   Method: Compositional matrix adjust.
 Identities = 24/75 (32%), Positives = 42/75 (56%), Gaps = 4/75 (5%)
 Frame = +3

Query: 33  EFKEAFNMIDQNRDGFIDKEDLHDMLASLGKNPTDAYLDAMMNEA----PGPINFTMFLT 88
           E +EAF + D++ +GFI   +L  ++ +LG+  TD  +D M+ EA     G +N+  F+ 
Sbjct: 30  ELREAFRVFDKDGNGFISASELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVK 209

Query: 89  MFGEKLNGTDPEDVI 103
           M   K + T  + +I
Sbjct: 210 MMTTK*SKTFLQTII 254
>18171
          Length = 1131

 Score = 66.2 bits (160), Expect = 7e-12,   Method: Compositional matrix adjust.
 Identities = 33/92 (35%), Positives = 52/92 (56%), Gaps = 3/92 (3%)
 Frame = +3

Query: 75  NEAPGPINFTMFLTMFGEKLNGTDPE---DVIRNAFACFDEEATGTIQEDYLRELLTTMG 131
           N   G ++F  FLT+    +   DP+   D +  A    D++ TG I    LR +LTT+G
Sbjct: 78  NSNQGKVDFPDFLTLMARTVGSKDPQEEDDAMLEALTLLDKDQTGVISTALLRHVLTTLG 257

Query: 132 DRFTDEEVDELYREAPIDKKGNFNYIEFTRIL 163
           D+ T EEV+EL +EA  ++ G  +Y EF +++
Sbjct: 258 DQLTSEEVEELIKEADKEETGQVDYKEFIKMM 353
>11425
          Length = 599

 Score = 57.4 bits (137), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 48/159 (30%), Positives = 71/159 (44%), Gaps = 11/159 (6%)
 Frame = -2

Query: 19  TSNVFAMFDQSQIQEFKEAFNMID--QNRDGFIDKEDLHDMLASLGKNPTDAYL-----D 71
           T+       +S I++  E F + D    RDG +D   + DM   LG NPT   +      
Sbjct: 598 TTCTMXSLSKSDIEDITEVFELFDFWDGRDGDVDAFKVGDMCFCLGLNPTQEIIRKNGGT 419

Query: 72  AMMNEAPGPIN--FTMFLTMFGEKLNGTDPEDVIRNAFACFDEEATGTIQEDYLRELLTT 129
             + E    +     ++ T+  EK  GT  +      F  FD E  G I    LR LLT 
Sbjct: 418 TKLGEKAYKLEEFLPIYETISKEKDTGTFAD--FMEGFKTFDREGQGFISAAELRHLLTG 245

Query: 130 MGDRFTDEEVDELYREAPI--DKKGNFNYIEFTRILKHG 166
           +G+R +D+EVDEL +      D +GN  Y +F + +  G
Sbjct: 244 LGERLSDDEVDELIKATDTREDLEGNVKYEDFIQKVLKG 128
>01019
          Length = 1705

 Score = 55.1 bits (131), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 28/68 (41%), Positives = 39/68 (57%), Gaps = 8/68 (11%)
 Frame = +1

Query: 109 CFDEEATGTIQEDYLRELLTTMGDRFTDEEVDELYREAPIDKKGNFNYIEFTRIL----- 163
            FD++  G I    LR ++T +G++ TDEEVDE+ REA ID  G  NY EF  ++     
Sbjct: 43  VFDKDGNGFISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVTMMTSK*A 222

Query: 164 ---KHGAK 168
               HGA+
Sbjct: 223 VQSAHGAR 246
>38338
          Length = 463

 Score = 53.9 bits (128), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 28/69 (40%), Positives = 43/69 (62%)
 Frame = -2

Query: 17  RATSNVFAMFDQSQIQEFKEAFNMIDQNRDGFIDKEDLHDMLASLGKNPTDAYLDAMMNE 76
            + SN+     + QI EFKEAF++ D++ DG I  ++L  ++ SLG+NPT+A L  M+NE
Sbjct: 213 HSKSNMADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINE 34

Query: 77  APGPINFTM 85
                N T+
Sbjct: 33  VDADGNGTI 7

 Score = 30.8 bits (68), Expect = 0.29,   Method: Compositional matrix adjust.
 Identities = 14/53 (26%), Positives = 28/53 (52%)
 Frame = -2

Query: 104 RNAFACFDEEATGTIQEDYLRELLTTMGDRFTDEEVDELYREAPIDKKGNFNY 156
           + AF+ FD++  GTI    L  ++ ++G   T+ E+ ++  E   D  G  ++
Sbjct: 159 KEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDF 1
>14945
          Length = 1337

 Score = 53.1 bits (126), Expect = 5e-08,   Method: Compositional matrix adjust.
 Identities = 31/93 (33%), Positives = 51/93 (54%), Gaps = 4/93 (4%)
 Frame = +1

Query: 28  QSQIQEFKEAFNMIDQNRDGFIDKEDLHDMLASLGKNPTDAYLDAMM----NEAPGPINF 83
           + Q QE +EAF++ D +  G ID ++L   + +LG  P    +  M+     E  G I+F
Sbjct: 100 EEQKQEIREAFDLFDADGSGTIDAKELKVAMRALGFEPKKEEIKKMIAEIDKEGTGTIDF 279

Query: 84  TMFLTMFGEKLNGTDPEDVIRNAFACFDEEATG 116
             FLT+  +K++  D ++ I  AF  FD++ TG
Sbjct: 280 NDFLTIMTQKMSEKDAKEEILKAFRLFDDDETG 378

 Score = 32.7 bits (73), Expect = 0.080,   Method: Compositional matrix adjust.
 Identities = 19/69 (27%), Positives = 33/69 (47%)
 Frame = +1

Query: 103 IRNAFACFDEEATGTIQEDYLRELLTTMGDRFTDEEVDELYREAPIDKKGNFNYIEFTRI 162
           IR AF  FD + +GTI    L+  +  +G     EE+ ++  E   +  G  ++ +F  I
Sbjct: 118 IREAFDLFDADGSGTIDAKELKVAMRALGFEPKKEEIKKMIAEIDKEGTGTIDFNDFLTI 297

Query: 163 LKHGAKDKD 171
           +     +KD
Sbjct: 298 MTQKMSEKD 324
>16255
          Length = 767

 Score = 43.5 bits (101), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 19/37 (51%), Positives = 26/37 (70%)
 Frame = -2

Query: 127 LTTMGDRFTDEEVDELYREAPIDKKGNFNYIEFTRIL 163
           +T +G++ TDEEVDE+ REA ID  G  NY EF  ++
Sbjct: 766 MTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVTMM 656
>19942
          Length = 367

 Score = 41.2 bits (95), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 17/31 (54%), Positives = 23/31 (74%)
 Frame = +2

Query: 126 LLTTMGDRFTDEEVDELYREAPIDKKGNFNY 156
           ++T +G++ TDEEVDE+ REA ID  G  NY
Sbjct: 2   VMTNLGEKLTDEEVDEMIREADIDGDGQVNY 94
>07385
          Length = 1292

 Score = 39.7 bits (91), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 17/31 (54%), Positives = 22/31 (70%)
 Frame = +3

Query: 133 RFTDEEVDELYREAPIDKKGNFNYIEFTRIL 163
           + TDEEVDE+ REA ID  G  NY EF +++
Sbjct: 150 KLTDEEVDEMIREADIDGDGQVNYEEFVKMM 242
>08108
          Length = 818

 Score = 38.5 bits (88), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 22/68 (32%), Positives = 36/68 (52%)
 Frame = +2

Query: 97  TDPEDVIRNAFACFDEEATGTIQEDYLRELLTTMGDRFTDEEVDELYREAPIDKKGNFNY 156
           TD E   + AFA FD + +G+I    L E L   G   TD++  EL ++   D  G+ + 
Sbjct: 119 TDAE--CQTAFAVFDTDGSGSISAGELGEALRAQGADITDDQTAELIKKYDSDSNGDIDT 292

Query: 157 IEFTRILK 164
            EF ++++
Sbjct: 293 DEFRKLVE 316
>01773
          Length = 1950

 Score = 36.6 bits (83), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 35/137 (25%), Positives = 59/137 (43%), Gaps = 11/137 (8%)
 Frame = +1

Query: 34  FKEAFNMIDQNRDGFIDKEDLHDMLASLGKNPTDAYLDAMMNEAPGP-----INFTMF-- 86
           +K+ F   D+N DG+++ ++L ++    G + +D+ +        GP     I F  F  
Sbjct: 160 YKQLFKEADKNNDGYLEIKELRELFKRNGSSLSDSQIADTFVFFDGPRGDKRITFEXFCK 339

Query: 87  ----LTMFGEKLNGTDPEDVIRNAFACFDEEATGTIQEDYLRELLTTMGDRFTDEEVDEL 142
               + MF +KL            F   D+   G +  D L+ LL   G +FT ++V  +
Sbjct: 340 GLDQIVMFVQKL---------AELFKAKDKSGDGYLDRDELKALLDESGQKFTADDVSAI 492

Query: 143 YREAPIDKKGNFNYIEF 159
            + A    K N N I F
Sbjct: 493 LKSAD---KNNDNKICF 534
>01491
          Length = 1707

 Score = 31.2 bits (69), Expect = 0.20,   Method: Compositional matrix adjust.
 Identities = 22/78 (28%), Positives = 39/78 (50%), Gaps = 11/78 (14%)
 Frame = +1

Query: 37  AFNMIDQNRDGFIDKEDLHDMLASLGKNPTDAYLDAMMNE----APGPINFTMFLTMFGE 92
           AF ++D+   G I  EDL  +L SLG + T+  ++ M+ E      G +++  F T+   
Sbjct: 361 AFRVLDKGNKGVIPVEDLRWLLKSLGDDLTEDEIEDMIVETDTDGSGTVDYEEFRTLMNS 540

Query: 93  -------KLNGTDPEDVI 103
                  +++   P+DVI
Sbjct: 541 A*RHLPTRVSHHIPDDVI 594
>19912
          Length = 865

 Score = 30.8 bits (68), Expect = 0.33,   Method: Compositional matrix adjust.
 Identities = 20/54 (37%), Positives = 24/54 (44%)
 Frame = +2

Query: 107 FACFDEEATGTIQEDYLRELLTTMGDRFTDEEVDELYREAPIDKKGNFNYIEFT 160
           F  FD+E T +I  D  R+ LT        +EVD L  E   D  G  NY E  
Sbjct: 686 FNKFDKEGTMSITRDQFRQGLTEASIPLAGDEVDFLLDELDRDGDGEINYSELV 847
>22273
          Length = 297

 Score = 30.4 bits (67), Expect = 0.38,   Method: Compositional matrix adjust.
 Identities = 13/25 (52%), Positives = 17/25 (68%)
 Frame = +1

Query: 139 VDELYREAPIDKKGNFNYIEFTRIL 163
           VDE+ REA ID  G  NY EF +++
Sbjct: 1   VDEMIREADIDGDGQVNYEEFVKMM 75
>37064
          Length = 715

 Score = 28.5 bits (62), Expect = 1.4,   Method: Compositional matrix adjust.
 Identities = 22/76 (28%), Positives = 36/76 (47%)
 Frame = -2

Query: 71  DAMMNEAPGPINFTMFLTMFGEKLNGTDPEDVIRNAFACFDEEATGTIQEDYLRELLTTM 130
           +++  E P  I  +    +   +LN   PED   N    F +  T ++ E+++R L+   
Sbjct: 384 ESLFAEIPIVIKNSPLTNIMMSELNELLPEDKGHN----FLDLGTASVLENHMRSLI--- 226

Query: 131 GDRFTDEEVDELYREA 146
                 E VDELY+EA
Sbjct: 225 ------ERVDELYQEA 196
>07678
          Length = 958

 Score = 27.3 bits (59), Expect = 3.2,   Method: Compositional matrix adjust.
 Identities = 10/18 (55%), Positives = 14/18 (77%)
 Frame = +1

Query: 101 DVIRNAFACFDEEATGTI 118
           DVI+  F CFD++ +GTI
Sbjct: 430 DVIQEMFTCFDKDZSGTI 483
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6755546|ref|NP_036107.1| solute carrier family 27,
member 1 [Mus musculus]
         (646 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

14264                                                                 273   1e-73
26510                                                                  42   0.001
20450                                                                  38   0.014
02291                                                                  32   0.71 
13819                                                                  32   0.74 
05061                                                                  30   4.4  
03756                                                                  29   5.2  
04020                                                                  29   6.1  
>14264
          Length = 1790

 Score =  273 bits (699), Expect = 1e-73,   Method: Compositional matrix adjust.
 Identities = 177/466 (37%), Positives = 246/466 (52%), Gaps = 14/466 (3%)
 Frame = -3

Query: 129  DVVAVFLEGRPEFXXXXXXXXXXXXXXXXXXXXXRREPLAFCLGTSAAKALIYGG--EMA 186
            D VA+ ++  P F                     R +PLA  +  +  KALI G   ++ 
Sbjct: 1383 DAVALMMQNEPAFMWTVLGLQKLGVAVALINHNLRAKPLAHAILAAEPKALIVGSGRDVQ 1204

Query: 187  AAVAEVSEQLGKSLLKFCSGDLGPESILPDTQLLDPMLAEA-PTTPLAQAPGKGMDDRL- 244
             A  ++ E +   +     G  G E++      LD ++ +A P  P      +  DD + 
Sbjct: 1203 QAAFDIQEHM-HGMPVLVQGLCG-EAVPAGMXDLDMLMTDALPVRPDPSLRSQMTDDTIG 1030

Query: 245  FYIYTSGTTGLPKAAIVVHSRYYRIAAFGHHSYSMRAADVLYDCLPLYHSAGNIMGVGQC 304
             YIYTSGTTGLPK  +  + +  ++         +   D++Y  LPLYH +   +G    
Sbjct: 1029 VYIYTSGTTGLPKP-VYYNQKKLKMFTTTAQLLDVTTQDIVYTVLPLYHISAFGVGFMGL 853

Query: 305  VIYGLTVVLRKKFSASRFWDDCVKYNCTVVQYIGEICRYLLRQPVRDVEQRHRVRLAVGN 364
            +  G T VL++KFSAS+FW DC  YN T+VQYIGE+ RYLL QP  +++  H+VR A+GN
Sbjct: 852  LHQGGTSVLKRKFSASQFWSDCRTYNVTIVQYIGELFRYLLAQPKSELDGVHKVRGAIGN 673

Query: 365  GLRPAIWEEFTQRFGVPQIGEFYGATECNCSIANMDGKVGSCGFNSRILTHV--YPIRLV 422
            GLR  I+EE   RF + Q+ EFY ATE    + NM  K G+ G  S  L  +  YP  +V
Sbjct: 672  GLRKDIFEEVLTRFKIIQVCEFYAATEGVSGLFNMFNKPGAIGRVSPFLNFLAPYPSVVV 493

Query: 423  KVNEDTMEPLRDSEGLCIPCQPGEPGLLVGQ----INQQDPLRRFDGYVSDSATNKKIAH 478
            K +  T  P+RD  G C+  +PGE GL + Q    I  Q  L  +    S  A  KK+  
Sbjct: 492  KFDYSTAMPVRDKNGRCVKVKPGEIGLFMSQVPDDIQTQGNLTVYKA--SKEANEKKLVR 319

Query: 479  SVFRKGDSAYLSGDVLVMDELGYMYFRDRSGDTFRWRGENVSTTEVEAVLSRLLGQTDVA 538
            + F++GD  +  GDV  +D+  ++YF DR GDTFRW+GENVSTTEV  VLS     +D  
Sbjct: 318  NAFKEGDLYFNYGDVFYLDKDYFVYFHDRIGDTFRWKGENVSTTEVSNVLSTPDFISDAN 139

Query: 539  VYGVAVPGVEGKAGMAAIA-DPHSQLDPNS---MYQELQKVLASYA 580
            VYGV VPG +G+AGMAA+  +  + L P     MY   Q  L SYA
Sbjct: 138  VYGVTVPGHDGRAGMAALTLNEGTTLAPEQLKZMYTLCQSELPSYA 1
>26510
          Length = 1692

 Score = 41.6 bits (96), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 38/149 (25%), Positives = 59/149 (39%), Gaps = 7/149 (4%)
 Frame = +1

Query: 242 DRLFYIYTSGTTGLPKAAIVVHSRYYRIAAFGHHSYSMRAADVLYDCLPLYHSAGNIMGV 301
           D LF  Y+SGTTGLPK  ++ H              + +  D     LP +H  G +  V
Sbjct: 700 DVLFLPYSSGTTGLPKGVMLSHRNIVANILQFRELANTQPEDRTLGLLPFFHIYG-LTCV 876

Query: 302 GQCVIY-GLTVVLRKKFSASRFWDDCVKYNCTVVQYIGEICRYLLRQP------VRDVEQ 354
               +Y G  +V   +F    F         T++Q +  +  +L R P      + +++ 
Sbjct: 877 QFGTLYDGAELVTVPRFEPELFLKSLHDRKITLLQAVPPVVLFLARHPMVSQFDLSNIKY 1056

Query: 355 RHRVRLAVGNGLRPAIWEEFTQRFGVPQI 383
            H     +G+G    I  E   R G P I
Sbjct: 1057MHSGAAPLGSG----ITIECQNRLGFPVI 1131
>20450
          Length = 775

 Score = 37.7 bits (86), Expect = 0.014,   Method: Compositional matrix adjust.
 Identities = 19/52 (36%), Positives = 29/52 (55%)
 Frame = -3

Query: 490 SGDVLVMDELGYMYFRDRSGDTFRWRGENVSTTEVEAVLSRLLGQTDVAVYG 541
           +GDV   D  G++Y  DR  +  +++GE V+   +E VL    G +D AV G
Sbjct: 455 TGDVGQFDSNGFLYIVDRKKELIKYKGEQVAPAMLEDVLLSHPGISDAAVIG 300
>02291
          Length = 3161

 Score = 32.0 bits (71), Expect = 0.71,   Method: Compositional matrix adjust.
 Identities = 22/71 (30%), Positives = 33/71 (46%), Gaps = 6/71 (8%)
 Frame = -1

Query: 247  IYTSGTTGLPKAAIVVHSRYYRIAAFGHHSYSMRAADVLY------DCLPLYHSAGNIMG 300
            IYTSGTTG PK  ++ H       A  + S +M+  +  +        LPL H A  +M 
Sbjct: 2846 IYTSGTTGTPKGVMLSHDNITYTVAV-NMSSTMQQLNTKFGQQSGISYLPLSHIAAQMMD 2670

Query: 301  VGQCVIYGLTV 311
            +   + +G T 
Sbjct: 2669 IYVXIGFGGTT 2637
>13819
          Length = 1080

 Score = 32.0 bits (71), Expect = 0.74,   Method: Compositional matrix adjust.
 Identities = 30/139 (21%), Positives = 58/139 (41%), Gaps = 5/139 (3%)
 Frame = +2

Query: 473 NKKIAHSVFRKGDSAYLSGDVLVMDELGYMYFRDRSGDTFRWRGENVSTTEVEAVLSRLL 532
           +++   + F+     Y +GD       G+     R  D     G  + T EVE VL   +
Sbjct: 26  HQRYIDTYFKPCPGVYYTGDGAHRHPGGFYQITGRMDDVVNVTGHRLGTAEVEDVLDDHV 205

Query: 533 GQTDVAVYGVAVPGVEGKAGMAAIADPHSQLDPN-----SMYQELQKVLASYARPIFLRL 587
              + AV G     ++G+   A +      ++ N      +   +++ +ASYA+P F+  
Sbjct: 206 DVAESAVVGFP-HDIKGEGIFAFVVLKERAMETNKEIEADLKAAIKQRIASYAQPDFILF 382

Query: 588 LPQVDTTGTFKIQKTRLQR 606
              +  T + KI +  L++
Sbjct: 383 TESLPKTRSGKIMRRVLRK 439
>05061
          Length = 1516

 Score = 29.6 bits (65), Expect = 4.4,   Method: Compositional matrix adjust.
 Identities = 18/55 (32%), Positives = 29/55 (52%)
 Frame = -1

Query: 513 RWRGENVSTTEVEAVLSRLLGQTDVAVYGVAVPGVEGKAGMAAIADPHSQLDPNS 567
           RWR  + STT  E +  +LLG+    V+G  V  V  + G  A+   H+ L+ ++
Sbjct: 223 RWRKSSSSTTLEEVLTGKLLGKL---VHGAVVVIVR*RHGCQAVGFVHAVLEKDN 68
>03756
          Length = 992

 Score = 29.3 bits (64), Expect = 5.2,   Method: Compositional matrix adjust.
 Identities = 12/26 (46%), Positives = 16/26 (61%)
 Frame = +2

Query: 241 DDRLFYIYTSGTTGLPKAAIVVHSRY 266
           DD     YTSGTTG PK  ++ H+ +
Sbjct: 722 DDLATLCYTSGTTGDPKGVMLTHANF 799
>04020
          Length = 1820

 Score = 28.9 bits (63), Expect = 6.1,   Method: Compositional matrix adjust.
 Identities = 12/30 (40%), Positives = 15/30 (50%)
 Frame = -1

Query: 363 GNGLRPAIWEEFTQRFGVPQIGEFYGATEC 392
           G GLRP  W   T+R  V +  +F    EC
Sbjct: 305 GLGLRPCEWHNSTRRTAVEETTQFLSCLEC 216
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|7106427|ref|NP_033315.1| STE20-like kinase [Mus
musculus]
         (1233 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

13212                                                                 275   1e-73
18921                                                                 183   4e-46
12721                                                                 170   3e-42
19094                                                                 118   1e-41
14420                                                                 154   1e-37
00300                                                                 140   4e-33
13592                                                                 120   2e-27
01707                                                                 108   1e-23
01756                                                                 106   7e-23
03240                                                                 103   3e-22
37602                                                                  93   2e-21
09606                                                                  92   2e-18
06405                                                                  87   4e-17
14126                                                                  87   6e-17
01718                                                                  84   3e-16
31885                                                                  83   9e-16
01060                                                                  82   2e-15
00392                                                                  81   3e-15
19761                                                                  80   6e-15
29581                                                                  77   6e-14
30755                                                                  75   1e-13
04591                                                                  75   1e-13
13066                                                                  75   2e-13
18484                                                                  75   2e-13
09007                                                                  72   2e-12
15910                                                                  72   2e-12
02638                                                                  69   1e-11
04138                                                                  69   2e-11
00715                                                                  68   2e-11
21079                                                                  67   6e-11
12786                                                                  66   8e-11
27405                                                                  66   8e-11
01392                                                                  66   1e-10
04852                                                                  65   1e-10
26560                                                                  65   2e-10
21808                                                                  64   4e-10
21210                                                                  64   4e-10
17975                                                                  64   6e-10
27546                                                                  63   7e-10
19301                                                                  63   8e-10
11780                                                                  63   8e-10
01966                                                                  62   2e-09
07940                                                                  62   2e-09
21433                                                                  54   8e-09
14116                                                                  60   8e-09
28638                                                                  59   1e-08
07291                                                                  57   5e-08
16708                                                                  55   2e-07
12672                                                                  55   2e-07
18996                                                                  50   6e-06
14477                                                                  50   6e-06
26711                                                                  49   1e-05
22005                                                                  48   2e-05
03508                                                                  48   2e-05
17253                                                                  47   4e-05
07833                                                                  47   6e-05
26009                                                                  32   1e-04
28157                                                                  45   2e-04
20640                                                                  44   3e-04
36481                                                                  44   4e-04
11185                                                                  44   5e-04
07836                                                                  44   6e-04
20559                                                                  44   6e-04
32691                                                                  43   6e-04
25019                                                                  42   0.002
31489                                                                  42   0.002
17300                                                                  41   0.003
29011                                                                  35   0.009
31789                                                                  39   0.012
17516                                                                  39   0.015
06358                                                                  38   0.022
08294                                                                  38   0.023
18481                                                                  37   0.033
01106                                                                  37   0.038
37063                                                                  37   0.039
00394                                                                  37   0.053
00486                                                                  37   0.065
21800                                                                  37   0.066
17806                                                                  37   0.072
32359                                                                  36   0.094
32000                                                                  35   0.13 
18663                                                                  35   0.16 
20152                                                                  35   0.18 
29360                                                                  35   0.19 
27274                                                                  34   0.36 
31120                                                                  33   0.97 
29590                                                                  32   1.3  
20513                                                                  31   2.8  
32957                                                                  31   3.4  
16350                                                                  30   5.8  
24241                                                                  30   7.7  
>13212
          Length = 1067

 Score =  275 bits (702), Expect = 1e-73,   Method: Compositional matrix adjust.
 Identities = 115/192 (59%), Positives = 159/192 (82%), Gaps = 3/192 (1%)
 Frame = -1

Query: 104  LWILIEF---CAGGAVDAVMLELERPLTESQIQVVCKQTLEALNYLHDNKIIHRDLKAGN 160
            +W +++       GA+D++M++LE+P+TE+QI  VC +   AL++LH + +IHRD+KAGN
Sbjct: 1067 VWXIVDVFRVLWWGALDSIMVDLEKPMTEAQICYVCHEMCMALDFLHRHHVIHRDIKAGN 888

Query: 161  ILFTLDGDIKLADFGVSAKNTRTIQRRDSFIGTPYWMAPEVVMCETSKDRPYDYKADVWS 220
            +L T+DG++KLADFGVSAKNT+T Q+RD+FIGTPYWMAPEVV+CET KD PYD+KAD+WS
Sbjct: 887  VLLTIDGEVKLADFGVSAKNTQTQQKRDTFIGTPYWMAPEVVLCETLKDTPYDFKADIWS 708

Query: 221  LGITLIEMAEIEPPHHELNPMRVLLKIAKSEPPTLAQPSKWSSNFKDFLRKCLEKNVDAR 280
            LG+TLIE A+IEPP+ E++PMRVL+KI KS+PPTL +P KW+  FKDF+ KCL K+ + R
Sbjct: 707  LGVTLIEFAQIEPPNKEMHPMRVLIKIHKSDPPTLEKPKKWTKLFKDFIAKCLVKDPNLR 528

Query: 281  WTTSQLLQHPFV 292
             T ++LL+HPF+
Sbjct: 527  PTAAELLEHPFM 492
>18921
          Length = 697

 Score =  183 bits (465), Expect = 4e-46,   Method: Composition-based stats.
 Identities = 90/208 (43%), Positives = 137/208 (65%)
 Frame = +2

Query: 30  PEEFWEIIGELGDGAFGKVYKAQNKETNVLAAAKVIDTKSEEELEDYMVEIDILASCDHP 89
           PE+ ++I+G+LG+G++G V+K+ +KET  + A K +   ++  L++ + EI I+  CD  
Sbjct: 23  PEDVFDILGKLGEGSYGSVFKSLHKETGQVLAIKQVPVDTD--LQEIIKEISIMQQCDSK 196

Query: 90  NIVKLLDAFYYENNLWILIEFCAGGAVDAVMLELERPLTESQIQVVCKQTLEALNYLHDN 149
            IVK   +++   +LWI++E+C  G+V  +M    + L E +I  +   TL+ L YLH  
Sbjct: 197 YIVKYYGSYFKNTDLWIVMEYCGAGSVSDIMRLRNKTLVEREIATILYYTLKGLXYLHSR 376

Query: 150 KIIHRDLKAGNILFTLDGDIKLADFGVSAKNTRTIQRRDSFIGTPYWMAPEVVMCETSKD 209
           + IHRD+KAGNIL   +G  KLADFGV+ + T T+ +R++ IGTPYWMAPEV+     ++
Sbjct: 377 RKIHRDIKAGNILLNNEGHAKLADFGVAGQLTDTMAKRNTVIGTPYWMAPEVI-----QE 541

Query: 210 RPYDYKADVWSLGITLIEMAEIEPPHHE 237
             YD  AD+WSLGIT +EMAE +PP  E
Sbjct: 542 IGYDCVADIWSLGITALEMAEGKPPVME 625
>12721
          Length = 821

 Score =  170 bits (430), Expect = 3e-42,   Method: Composition-based stats.
 Identities = 91/272 (33%), Positives = 154/272 (56%)
 Frame = +1

Query: 11  KLGSEKKKKQYEHVKRDLNPEEFWEIIGELGDGAFGKVYKAQNKETNVLAAAKVIDTKSE 70
           +L  E+ +   + V    +P  F +   ++G+G+ G V  A +++   +A  K +D + +
Sbjct: 25  RLSHEQFRAALQMVVTPGDPRTFLDDFMKIGEGSTGIVCIATSRDGRQMAVKK-MDLRKQ 201

Query: 71  EELEDYMVEIDILASCDHPNIVKLLDAFYYENNLWILIEFCAGGAVDAVMLELERPLTES 130
           +  E    E+ ++    HPNIV++ +++   + LW+++EF  GGA+  ++      + E 
Sbjct: 202 QRRELLFNEVVVMRDYHHPNIVEMYNSYLVNDELWVVMEFMEGGALTDIVTN--NRMDEV 375

Query: 131 QIQVVCKQTLEALNYLHDNKIIHRDLKAGNILFTLDGDIKLADFGVSAKNTRTIQRRDSF 190
           QI  VC+  L+AL +LH N +IHRD+K+ +IL + DG +KL DFG  A+ T+ +Q+R S 
Sbjct: 376 QIATVCRACLKALAFLHANGVIHRDIKSDSILLSHDGKVKLXDFGFCAQVTQDLQKRKSL 555

Query: 191 IGTPYWMAPEVVMCETSKDRPYDYKADVWSLGITLIEMAEIEPPHHELNPMRVLLKIAKS 250
           +GTPYWMAPEV+        PY  + D+WSLGI ++EM + EPP     P++ + +I   
Sbjct: 556 VGTPYWMAPEVI-----SRLPYGPEVDIWSLGIMVMEMIDAEPPFFNEPPLQAMRRIRDM 720

Query: 251 EPPTLAQPSKWSSNFKDFLRKCLEKNVDARWT 282
            PP L    K S   + F+ + L ++   R T
Sbjct: 721 PPPKLRNTHKISPRLQGFIDRMLVRDPHQRAT 816
>19094
          Length = 898

 Score =  118 bits (296), Expect(2) = 1e-41,   Method: Composition-based stats.
 Identities = 58/119 (48%), Positives = 78/119 (65%)
 Frame = +1

Query: 112 AGGAVDAVMLELERPLTESQIQVVCKQTLEALNYLHDNKIIHRDLKAGNILFTLDGDIKL 171
             G+V  +M    + L E +I  +   TL+ L YLH  + IHRD+KAGNIL   +G  KL
Sbjct: 4   GAGSVSDIMRLRNKTLVEREIATILYYTLKGL*YLHSRRKIHRDIKAGNILLNNEGHAKL 183

Query: 172 ADFGVSAKNTRTIQRRDSFIGTPYWMAPEVVMCETSKDRPYDYKADVWSLGITLIEMAE 230
           ADFGV+ + T T+ +R++ IGTPYWMAPEV+     ++  YD  AD+WSLGIT +EMAE
Sbjct: 184 ADFGVAGQLTDTMAKRNTVIGTPYWMAPEVI-----QEIGYDCVADIWSLGITALEMAE 345

 Score = 71.2 bits (173), Expect(2) = 1e-41,   Method: Compositional matrix adjust.
 Identities = 28/61 (45%), Positives = 39/61 (63%)
 Frame = +3

Query: 232 EPPHHELNPMRVLLKIAKSEPPTLAQPSKWSSNFKDFLRKCLEKNVDARWTTSQLLQHPF 291
           +PP+ +++PMR +  I    PP+  QP KWS+ F DF+ KCL KN + R T   LLQH F
Sbjct: 348 KPPYGDIHPMRAIFMIPTKPPPSFRQPDKWSTEFIDFVSKCLVKNPENRATAVDLLQHDF 527

Query: 292 V 292
           +
Sbjct: 528 I 530
>14420
          Length = 528

 Score =  154 bits (390), Expect = 1e-37,   Method: Compositional matrix adjust.
 Identities = 73/166 (43%), Positives = 106/166 (63%)
 Frame = +2

Query: 79  EIDILASCDHPNIVKLLDAFYYENNLWILIEFCAGGAVDAVMLELERPLTESQIQVVCKQ 138
           EI ++    +PNIV  LD++     LW+++EF AGG++  V+ E    + E QI  VC++
Sbjct: 50  EILVMRENQNPNIVNYLDSYLVGEELWVVMEFLAGGSLTDVVTE--TCMDEGQIAAVCRE 223

Query: 139 TLEALNYLHDNKIIHRDLKAGNILFTLDGDIKLADFGVSAKNTRTIQRRDSFIGTPYWMA 198
            L+AL +LH+N++IHRD+K+ NIL  +DG +KL DFG  A+ +    +R + +GTPYWMA
Sbjct: 224 CLQALEFLHENQVIHRDIKSDNILLGMDGSVKLTDFGFCAQLSPEQSKRSTMVGTPYWMA 403

Query: 199 PEVVMCETSKDRPYDYKADVWSLGITLIEMAEIEPPHHELNPMRVL 244
           PEVV       + Y    D+WSLG+  IEM E EPP+   NP+R L
Sbjct: 404 PEVV-----TRKQYGPTVDIWSLGVMCIEMIEGEPPYLNENPLRAL 526
>00300
          Length = 2318

 Score =  140 bits (352), Expect = 4e-33,   Method: Compositional matrix adjust.
 Identities = 94/294 (31%), Positives = 148/294 (50%), Gaps = 7/294 (2%)
 Frame = -1

Query: 8    KIFKLGSEKKKKQYEHVKRDLNPEEFWEIIGELGDGAFGKVYKAQNKETNVLAAAKVIDT 67
            +I ++ ++ ++  Y    R +N    W+   ++G+G FGKVY A N  T  L A K +  
Sbjct: 1724 RIGRVAAKPREPDYRINVRRVNFR--WQRGNKIGEGQFGKVYTAVNMSTGELMALKEMKF 1551

Query: 68   KSE--EELEDYMVEIDILASCDHPNIVKLLDAFYYENNLWILIEFCAGGAVDAVMLELER 125
            +    ++L +   EI I     H N+VK      +++ + + +E+C  G ++      + 
Sbjct: 1550 QPNDLQQLREMCDEIKIFEGIQHENLVKYYGVEVHKDEMLMFMEYCDTGTIEEAA---KM 1380

Query: 126  PLTESQIQVVCKQTLEALNYLHDNKIIHRDLKAGNILFTLDGDIKLADFGVSAK---NTR 182
             L E  I+   ++ + A+N+LH+N I+HRD+K  NI  T +G +KL DFG S K   +T 
Sbjct: 1379 GLPEYLIRRYTREIVLAVNHLHENSIVHRDIKGANIFLTSNGHVKLGDFGCSVKLKSHTT 1200

Query: 183  TIQRRDSFIGTPYWMAPEVVMCETSKDR-PYDYKADVWSLGITLIEMAEIEPPHHEL-NP 240
                  + +GT  +MAPEV    T  D+  Y   AD+WSLG  +IEMA  + P H+L N 
Sbjct: 1199 MPGEFHNLVGTTAYMAPEVF---TQNDQGGYGRAADIWSLGCVVIEMATGKRPWHDLDNN 1029

Query: 241  MRVLLKIAKSEPPTLAQPSKWSSNFKDFLRKCLEKNVDARWTTSQLLQHPFVTV 294
             +++ K+     P  A P   S   K FL   +  +   R   SQLL H F  V
Sbjct: 1028 YQIMYKVGIGHKP--AVPDSLSVEGKHFLDLIMCHDPAQRALASQLLDHTFTKV 873
>13592
          Length = 980

 Score =  120 bits (302), Expect = 2e-27,   Method: Compositional matrix adjust.
 Identities = 83/261 (31%), Positives = 132/261 (50%), Gaps = 8/261 (3%)
 Frame = +2

Query: 39  ELGDGAFGKVYKAQNKETNVLAAAKVIDTKSEE--ELEDYMVEIDILASCDHPNIVKLLD 96
           ++G G FGKVY A N  T  L A K I  +  E   L++   E+ IL    H N+V+   
Sbjct: 5   KIGQGRFGKVYTAVNNNTGELMAMKEIAIQPGETRALKNVAEELKILEGIKHKNLVRYYG 184

Query: 97  AFYYENNLWILIEFCAGGAVDAVMLELERPLTESQIQVVCKQTLEALNYLHDNKIIHRDL 156
              +   L I +E C+ G +++ ++EL   L E+  +    Q L  +  LH + I+HRD+
Sbjct: 185 IEVHREELLIFMELCSEGTLES-LVELTGGLPEALSRRFTAQLLSGVAELHKHGIVHRDI 361

Query: 157 KAGNILFTLDG--DIKLADFGVSAK---NTRTIQRRDSFIGTPYWMAPEVVMCETSKDRP 211
           K  NI F +DG   +KL DFG + K   +T        ++GT  +MAPE V  +T+ D  
Sbjct: 362 KTANI-FLVDGSNSLKLGDFGSAVKIQAHTTVPGELQGYVGTQAYMAPE-VFTKTNSD-G 532

Query: 212 YDYKADVWSLGITLIEMAEIEPPHHELNP-MRVLLKIAKSEPPTLAQPSKWSSNFKDFLR 270
           +   AD+WS+G  ++EMA  + P  + +   +++ K+   E P    P   S    DF+ 
Sbjct: 533 HGRLADIWSVGCVVVEMASGKRPWAQFDSNFQIMFKVGMGEKPQ--APESLSQEGHDFID 706

Query: 271 KCLEKNVDARWTTSQLLQHPF 291
            CL+ +   R +  +LL+  F
Sbjct: 707 HCLQHDPKQRLSAIELLEQNF 769
>01707
          Length = 757

 Score =  108 bits (271), Expect = 1e-23,   Method: Composition-based stats.
 Identities = 69/203 (33%), Positives = 112/203 (55%), Gaps = 6/203 (2%)
 Frame = +1

Query: 32  EFWEIIGELGDGAFGKVYKAQNKETNVLAAAKVIDTKSEEEL--EDYMVEIDILASCDHP 89
           E +E IG++G+G++G V+K +NKET+ L A K      ++ L  +  M EI +L    HP
Sbjct: 64  EKYEKIGKIGEGSYGVVFKCRNKETSQLVAIKKFVESEDDPLIKKIAMREIRMLKQLKHP 243

Query: 90  NIVKLLDAFYYENNLWILIEFCAGGAVDAVML-ELER---PLTESQIQVVCKQTLEALNY 145
           N+V+L++ F  +  L ++ ++     VD  +L EL+R    L E  ++ +  QTL A+N+
Sbjct: 244 NLVRLIEVFRRKKRLHLVFDY-----VDHTLLNELDRYPRGLPEPMVKRIIYQTLLAVNF 408

Query: 146 LHDNKIIHRDLKAGNILFTLDGDIKLADFGVSAKNTRTIQRRDSFIGTPYWMAPEVVMCE 205
            H    IHRD+K  NIL T  G +KL DFG +   T        ++ T ++ APE+++ +
Sbjct: 409 CHQYNTIHRDVKPENILITRQGQVKLCDFGFARILTGPGDEYTDYVATRWYRAPELLVGD 588

Query: 206 TSKDRPYDYKADVWSLGITLIEM 228
           T    P     DVW++G    E+
Sbjct: 589 TQYGPP----VDVWAIGCVFAEL 645
>01756
          Length = 1858

 Score =  106 bits (264), Expect = 7e-23,   Method: Compositional matrix adjust.
 Identities = 70/216 (32%), Positives = 113/216 (52%), Gaps = 16/216 (7%)
 Frame = -3

Query: 34   WEIIGELGDGAFGKVYKAQNKETNVLAAAK--VIDTKSEEELEDYMVEIDILASCDHPNI 91
            +E + ++G G FG+V+KA+ K+T  + A K  ++D + E      + EI IL   +H N+
Sbjct: 1736 YEKLAKIGQGTFGEVFKARCKKTKQVVAMKKVLMDNEKEGFPITALREIKILQLLNHENV 1557

Query: 92   VKLLD--------AFYYENNLWILIEFC---AGGAVDAVMLELERPLTESQIQVVCKQTL 140
            V L++        A  Y++  +++ EFC     G +  + +    P    +I+ V KQ +
Sbjct: 1556 VDLIEICSTKATSANRYKSMFYLVFEFCEHDLAGLLSNMSVVFNLP----EIKEVMKQLM 1389

Query: 141  EALNYLHDNKIIHRDLKAGNILFTLDGDIKLADFGVS---AKNTRTIQRRDSFIGTPYWM 197
              L Y+H NKI+HRD+KA NIL T  G +KLADFG++   + N R   R  + + T ++ 
Sbjct: 1388 NGLYYIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRVVTLWYR 1209

Query: 198  APEVVMCETSKDRPYDYKADVWSLGITLIEMAEIEP 233
             PE+++     DR Y    D W  G  + EM    P
Sbjct: 1208 PPELLL----GDRNYSTAIDQWGAGCIMAEMWTRNP 1113
>03240
          Length = 1683

 Score =  103 bits (258), Expect = 3e-22,   Method: Compositional matrix adjust.
 Identities = 82/301 (27%), Positives = 131/301 (43%), Gaps = 56/301 (18%)
 Frame = -3

Query: 16   KKKKQYEHVKRDLNPEEFWEIIGELGDGAFGKVYKAQNKETNVLAAAKVI---DTKSEEE 72
            +K+  Y  +KR    +  +E I  LG GAFG+V   +  +T +L A K +   D     +
Sbjct: 1339 QKESNYIRLKRAKMDKCMFEKIKTLGVGAFGEVSLCRKNDTGMLYAMKTLRKSDVLKRNQ 1160

Query: 73   LEDYMVEIDILASCDHPNIVKLLDAFYYENNLWILIEFCAGGAVDAVMLELERPLTESQI 132
            +     E DILA  D+  +VKL  +F   N L+ ++++  GG +  +++ +E  L E   
Sbjct: 1159 VAHVKAERDILAEADNEWVVKLYYSFQDHNYLYFVMDYVPGGDLMGLLIRME-ILDEPLA 983

Query: 133  QVVCKQTLEALNYLHDNKIIHRDLKAGNILFTLDGDIKLADFGVS-----AKNTRTIQR- 186
            +    + ++A+  +H    IHRD+K  NIL   +G IKL DFG+        N++  QR 
Sbjct: 982  RFYVAELVQAIESVHRMGFIHRDIKPDNILIDRNGHIKLTDFGLCTGFRWTHNSKYYQRD 803

Query: 187  --------------------------------------RDSFIGTPYWMAPEVVMCETSK 208
                                                    S +GTP ++APEV+    S+
Sbjct: 802  GTHARQDSMEVKCQLDEQCQCEILKPLERRRKREQRCLAHSLVGTPNYIAPEVL----SR 635

Query: 209  DRPYDYKADVWSLGITLIEMAEIEPPHHELNP---------MRVLLKIAKSEPPTLAQPS 259
               Y    D WS+G+ L EM    PP +   P          + +LKI +     L+QP+
Sbjct: 634  LGGYTSVCDWWSVGVILFEMLVGHPPFYANTPAETQYKVINWKDMLKIPRES--NLSQPA 461

Query: 260  K 260
            K
Sbjct: 460  K 458
>37602
          Length = 804

 Score = 93.2 bits (230), Expect(3) = 2e-21,   Method: Composition-based stats.
 Identities = 45/108 (41%), Positives = 69/108 (63%), Gaps = 5/108 (4%)
 Frame = -1

Query: 92  VKLLDAFYYENNLWILIEFCAGGAVDAVMLELERPLTESQIQVVCKQTLEALNYLHDNKI 151
           V   D++     LWI +E+C GG++  +   +  PLTE QI  VC++TL+ L+YLH    
Sbjct: 330 VGYFDSYLRREKLWIAMEYCGGGSMQDIY-HVTGPLTEPQIAFVCRETLKGLHYLHRRGK 154

Query: 152 IHRDLKAGNILFTLDGDIKLADF-GVSAKNTRTIQRR----DSFIGTP 194
           +HRD+K  NIL T +GD+KLADF  VS+ ++  +Q++    ++FIG P
Sbjct: 153 MHRDIKGANILLTEEGDVKLADFWRVSSNHSHNVQKKVFHWNAFIGWP 10

 Score = 27.3 bits (59), Expect(3) = 2e-21,   Method: Compositional matrix adjust.
 Identities = 14/37 (37%), Positives = 19/37 (51%)
 Frame = -3

Query: 59  LAAAKVIDTKSEEELEDYMVEIDILASCDHPNIVKLL 95
           LAA KVI  +  ++      EI ++  C HPNI  L 
Sbjct: 430 LAAFKVIKLEPGDDFAIIQQEILMMKDCKHPNICWLF 320

 Score = 21.2 bits (43), Expect(3) = 2e-21,   Method: Composition-based stats.
 Identities = 7/7 (100%), Positives = 7/7 (100%)
 Frame = -3

Query: 195 YWMAPEV 201
           YWMAPEV
Sbjct: 22  YWMAPEV 2

 Score = 47.0 bits (110), Expect(2) = 1e-05,   Method: Composition-based stats.
 Identities = 21/46 (45%), Positives = 33/46 (71%)
 Frame = -1

Query: 172 ADFGVSAKNTRTIQRRDSFIGTPYWMAPEVVMCETSKDRPYDYKAD 217
           ADFGVSA+ T T+ +R SFIGTPYWMA +     + +++ ++++ D
Sbjct: 747 ADFGVSAQITATMCKRKSFIGTPYWMARKNRRLLSVENKVWNHRPD 610

 Score = 20.8 bits (42), Expect(2) = 1e-05,   Method: Compositional matrix adjust.
 Identities = 10/18 (55%), Positives = 12/18 (66%), Gaps = 3/18 (16%)
 Frame = -2

Query: 160 NILFTLDGDIK---LADF 174
           NIL T +GD+K   L DF
Sbjct: 803 NILLTEEGDVKLVCLCDF 750

 Score = 32.7 bits (73), Expect = 0.83,   Method: Composition-based stats.
 Identities = 15/26 (57%), Positives = 18/26 (69%)
 Frame = -2

Query: 174 FGVSAKNTRTIQRRDSFIGTPYWMAP 199
           FGVSA+ T T+ +R SFIGTP    P
Sbjct: 86  FGVSAQITATMCKRKSFIGTPLLDGP 9
>09606
          Length = 1300

 Score = 91.7 bits (226), Expect = 2e-18,   Method: Compositional matrix adjust.
 Identities = 77/295 (26%), Positives = 130/295 (44%), Gaps = 30/295 (10%)
 Frame = -3

Query: 39   ELGDGAFGKVYKAQNKETNVLAAAKVIDTKSEEELEDYMVEIDILASCDHPNIVKLLDAF 98
            ELG G    +YK + K T    A   I+     E+ +    + +     HPN+V+  + +
Sbjct: 1094 ELGKGEHSIIYKGRRKGTINFVAIHCIEKCKRPEVTN---TVRMTHDISHPNVVQFHEWY 924

Query: 99   YYENNLWILIEFCAGGAVDAVMLELERPLTESQIQVVCKQTLEALNYLHDNKIIHRDLKA 158
               N+LW+++E C GG++ A +L  +  L E+ I+      +  L+Y+H   I+  DL+ 
Sbjct: 923  ETSNHLWLVVELCTGGSL-ADILAQDHHLPETSIRDFGIHLVTGLHYIHSLGILFHDLRP 747

Query: 159  GNILFTLDGDIKLADFGVS----------------AKNTRTIQRRDSFI------GTPYW 196
              +L    G +K ADFG+S                A +   IQ  +  +      G+P +
Sbjct: 746  SKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEAGDQWNIQSAEEMMKQVPTSGSPTY 567

Query: 197  MAPEVVMCETSKDRPYDYKADVWSLGITLIEMAEIEPPH----HELNPMRVL---LKIAK 249
            MAPEV         P    +D+W+LG    EM    PP     +++   +VL     + K
Sbjct: 566  MAPEVF----QGAEP-SIMSDLWALGCVFYEMFSGHPPFLGETYDITKDKVLNKEFPLPK 402

Query: 250  SEPPTL-AQPSKWSSNFKDFLRKCLEKNVDARWTTSQLLQHPFVTVDSNKPVREL 303
             +   L A+PS     F + L   L+K+   R + + L++H F     +  V+E 
Sbjct: 401  VKGSRLSAKPSP---EFLNLLESLLQKDSTRRLSWASLVKHAFWQGGLSSLVKEF 246
>06405
          Length = 1965

 Score = 87.0 bits (214), Expect = 4e-17,   Method: Compositional matrix adjust.
 Identities = 58/199 (29%), Positives = 93/199 (46%), Gaps = 9/199 (4%)
 Frame = +1

Query: 40  LGDGAFGKVYKAQNKETNVLAAAKVI--DTKSEEELEDYMVEIDILASCDHPNIVKLLDA 97
           LG G +G VY+A  K  N + A K +  DT +   L D++ E  I+    HPN+V+LL  
Sbjct: 283 LGGGQYGDVYEAMWKRYNKIVAVKTLKEDTMA---LNDFLEEAAIMKEMKHPNLVQLLGV 453

Query: 98  FYYENNLWILIEFCA-GGAVDAVMLELERPLTESQIQVVCKQTLEALNYLHDNKIIHRDL 156
              E   +I+ EF   G  +D +          + +  +  Q    + YL     IHRDL
Sbjct: 454 CTREPPFYIVTEFMPHGNLLDYLRSSTREENGPTALMYMATQIASGMAYLETKNFIHRDL 633

Query: 157 KAGNILFTLDGDIKLADFGVSAKNTRTIQRRDSF---IGTPY---WMAPEVVMCETSKDR 210
            A N L      +K+ADFG++      + + D++   IG  +   W APE +        
Sbjct: 634 AARNCLVADSNMVKVADFGLA-----RLMKDDTYTAHIGAKFPIKWTAPEGLAFNR---- 786

Query: 211 PYDYKADVWSLGITLIEMA 229
            +  ++D+W+ G+ L E+A
Sbjct: 787 -FSTRSDIWAFGVLLWELA 840
>14126
          Length = 1265

 Score = 86.7 bits (213), Expect = 6e-17,   Method: Compositional matrix adjust.
 Identities = 66/215 (30%), Positives = 108/215 (50%), Gaps = 11/215 (5%)
 Frame = +3

Query: 25  KRDLNPEEFWEIIGELGDGAFGKVYKAQN-KETNVLAAAKVIDTKSEEELEDYMV--EID 81
           +RD + E+ +E +  +G+GA+G VYKA++ +      A K I   + EE    M   EI 
Sbjct: 171 RRD-STEQKYEEVAVIGNGAYGTVYKARDLRNQGEFVAMKRIRLNNTEEGMPMMAIREIS 347

Query: 82  ILASCD---HPNIVKLLDAFY-----YENNLWILIEFCAGGAVDAVMLELERPLTESQIQ 133
           +L   +   HPN+V+LLD  +      E  L ++ E+        +       L   +I+
Sbjct: 348 MLKQLEQYEHPNVVRLLDVSHNTITDREIRLNLVFEYIEHDLATYLAKCPSPGLGPDRIK 527

Query: 134 VVCKQTLEALNYLHDNKIIHRDLKAGNILFTLDGDIKLADFGVSAKNTRTIQRRDSFIGT 193
            +  Q L  +++LH N+I+HRDLK  N+L + DG +KLADFG+ A+         + + T
Sbjct: 528 DLMLQLLNGVDFLHSNRIVHRDLKPQNLLISKDGRLKLADFGL-ARIYSFHMALTTVVVT 704

Query: 194 PYWMAPEVVMCETSKDRPYDYKADVWSLGITLIEM 228
            ++ +PEV+M        Y    D+WS G    E+
Sbjct: 705 LWYRSPEVLM-----QAEYGTSVDIWSCGCIFAEL 794
>01718
          Length = 959

 Score = 84.0 bits (206), Expect = 3e-16,   Method: Compositional matrix adjust.
 Identities = 57/210 (27%), Positives = 105/210 (50%), Gaps = 5/210 (2%)
 Frame = +3

Query: 36  IIGELGDGAFGKVYKAQNKETNVLAAAKVIDTKSEEELEDYMVEIDILASCDHPNIVKLL 95
           I  ++G G F +V+K  ++ T  + A K+    S     + + E+ +L    H NI++ +
Sbjct: 159 ICEKIGAGFFSEVFKVTHRITGQVMALKMNTMTSNRH--NMLREVQLLNRLQHANILRFM 332

Query: 96  DAFYYENNLWILIEFCAGGAVDAVMLELERPLTESQIQVVCKQTLEALNYLHDNKIIHRD 155
               +E  L  L E+   G ++ ++ + +  L  +Q   +       L+YLH  + IHRD
Sbjct: 333 GVCVHEGQLHALTEYIPSGNLEQLLEKKDEELPWTQRIQLTLGLARGLDYLHSTRFIHRD 512

Query: 156 LKAGNILFTLDGD----IKLADFGVSAKNTRTIQR-RDSFIGTPYWMAPEVVMCETSKDR 210
           L + NIL   + +      +ADFG++ K    + + +   +G+PYWMAPEV+        
Sbjct: 513 LTSKNILIRREDNHGYHAVIADFGLATKIPDPLDKEKLPTVGSPYWMAPEVL-----NGH 677

Query: 211 PYDYKADVWSLGITLIEMAEIEPPHHELNP 240
            Y+ +AD++S+GI + E+    P   ++ P
Sbjct: 678 FYNERADLFSVGIIMCEITARIPADPDIMP 767
>31885
          Length = 529

 Score = 82.8 bits (203), Expect = 9e-16,   Method: Composition-based stats.
 Identities = 51/155 (32%), Positives = 78/155 (50%)
 Frame = -2

Query: 80  IDILASCDHPNIVKLLDAFYYENNLWILIEFCAGGAVDAVMLELERPLTESQIQVVCKQT 139
           +D+L   DHP +V L  AF  E +L+++++   GG +   M + E    E  ++    Q 
Sbjct: 519 VDMLTRLDHPFLVNLWYAFQDEEDLFMVVDLFLGGDLRYHMQQ-EVSFREDCVKFYLCQL 343

Query: 140 LEALNYLHDNKIIHRDLKAGNILFTLDGDIKLADFGVSAKNTRTIQRRDSFIGTPYWMAP 199
              L+YL   KI+HRD+K  NIL    G   + DF + A      +   S  GT  +MAP
Sbjct: 342 ALVLDYLRSQKIVHRDIKPDNILLDEQGHCHVTDFNI-ATQLEDDELATSTSGTRPYMAP 166

Query: 200 EVVMCETSKDRPYDYKADVWSLGITLIEMAEIEPP 234
           EV     ++ R Y +  D WSLG++L E+ +   P
Sbjct: 165 EVYGVAINERRGYGFPVDWWSLGVSLFELLKKRRP 61
>01060
          Length = 1800

 Score = 81.6 bits (200), Expect = 2e-15,   Method: Compositional matrix adjust.
 Identities = 58/200 (29%), Positives = 98/200 (49%), Gaps = 10/200 (5%)
 Frame = +1

Query: 39  ELGDGAFGKVYKAQNKETNVLAAAKVIDTKSEEEL--EDYMVEIDILASCDHPNIVKLLD 96
           ++G+G +G VYK +++ T    A K I  +  E+      + EI +L    H NIV L D
Sbjct: 94  KIGEGTYGVVYKCRHRATGRKLAMKKIRLRGSEDGVPSSAIREIAMLRELRHTNIVCLED 273

Query: 97  AFYYENNLWILIEFCAGGAVDAVM--------LELERPLTESQIQVVCKQTLEALNYLHD 148
               +  L+++ EF +   +D  M        + L+R L +S +     Q +  + + H 
Sbjct: 274 VIMEDERLFLVFEFLS---MDLKMYIDKFPEGVVLDRRLVKSYVF----QIVTGIXFCHQ 432

Query: 149 NKIIHRDLKAGNILFTLDGDIKLADFGVSAKNTRTIQRRDSFIGTPYWMAPEVVMCETSK 208
            +I+HRDLK  N+L    G IK+ADFG++      ++     + T ++ APE++M  +  
Sbjct: 433 RRIVHRDLKPQNLLINHTGAIKIADFGMARTFALPVRAYTHEVVTLWYRAPEILMGASKY 612

Query: 209 DRPYDYKADVWSLGITLIEM 228
             P     DVWS+G    +M
Sbjct: 613 STP----VDVWSIGTIFADM 660
>00392
          Length = 668

 Score = 80.9 bits (198), Expect = 3e-15,   Method: Compositional matrix adjust.
 Identities = 52/173 (30%), Positives = 90/173 (52%), Gaps = 12/173 (6%)
 Frame = +3

Query: 79  EIDILASCDHPNIVKLLDAFYYENN------LWILIEFCAGGAVDAVMLELERPLTESQI 132
           E ++L    HPNIV+  D ++ E+N      + ++ E    G +   +   ++P     +
Sbjct: 81  EAEMLKELQHPNIVRFFD-YWEEHNHRNRKVIILVTELMTSGTLKTYLKRFKKP----NV 245

Query: 133 QVV---CKQTLEALNYLHDNK--IIHRDLKAGNILFT-LDGDIKLADFGVSAKNTRTIQR 186
           +++   C+Q L+ L +LH     +IHRDLK  NI  T   G +K+ D G++    ++  +
Sbjct: 246 KILKNWCRQVLKGLYFLHTRTPPVIHRDLKCDNIFITGPTGSVKIGDLGLATLKNQSFAK 425

Query: 187 RDSFIGTPYWMAPEVVMCETSKDRPYDYKADVWSLGITLIEMAEIEPPHHELN 239
             S IGTP +MAPE+       +  YD   DV++ G+ ++EMA  E P+ E +
Sbjct: 426 --SVIGTPEFMAPEMY------EEHYDEAVDVYAFGMCMLEMASSEYPYSECS 560
>19761
          Length = 473

 Score = 79.7 bits (195), Expect = 6e-15,   Method: Composition-based stats.
 Identities = 48/147 (32%), Positives = 79/147 (53%), Gaps = 4/147 (2%)
 Frame = -3

Query: 134 VVC--KQTLEALNYLHDNK--IIHRDLKAGNILFTLDGDIKLADFGVSAKNTRTIQRRDS 189
           +VC   QT  ALNY+H +   I+HRDLK  NI  T  GD++L D G++ K T       S
Sbjct: 417 IVCWLMQTASALNYMHTHTPVILHRDLKPQNIYVTEKGDVRLGDLGLARKLTGPADFATS 238

Query: 190 FIGTPYWMAPEVVMCETSKDRPYDYKADVWSLGITLIEMAEIEPPHHELNPMRVLLKIAK 249
            +GT  +++PE++       +PY+ K+D+WSLG    ++   +    E+  M +L+++  
Sbjct: 237 QVGTIMYLSPEIL-----SQQPYNSKSDIWSLGCVFYDITG-KKGSDEMGVMFLLVQVMG 76

Query: 250 SEPPTLAQPSKWSSNFKDFLRKCLEKN 276
                L  P  +S  F+D + + L K+
Sbjct: 75  GR--KLPLPDHYSQEFRDTISRMLTKD 1
>29581
          Length = 1278

 Score = 76.6 bits (187), Expect = 6e-14,   Method: Compositional matrix adjust.
 Identities = 47/158 (29%), Positives = 86/158 (54%), Gaps = 2/158 (1%)
 Frame = -2

Query: 78   VEIDILASCDHPNIVKLLDAFYYE--NNLWILIEFCAGGAVDAVMLELERPLTESQIQVV 135
            V    L +  H NIV+L +    +  ++L++++E+C    + +++  +  P +ESQ++ +
Sbjct: 1208 VRSTFLLNLRHQNIVQLQEVVVGKSLDSLFLVMEYCEQD-LASLLDNMPAPFSESQVKCI 1032

Query: 136  CKQTLEALNYLHDNKIIHRDLKAGNILFTLDGDIKLADFGVSAKNTRTIQRRDSFIGTPY 195
              Q L+ L YLH+  IIHRDLK  N+L T  G +K+ADFG++    +  +     + T +
Sbjct: 1031 VLQLLKGLRYLHEAFIIHRDLKVSNLLMTDKGCVKIADFGLARNYGKPQKPMTPKVVTLW 852

Query: 196  WMAPEVVMCETSKDRPYDYKADVWSLGITLIEMAEIEP 233
            + APE++       + +    D+WS G  L E+   +P
Sbjct: 851  YRAPELLF----GSKTHSTAIDMWSAGCILGELLGHKP 750
>30755
          Length = 1137

 Score = 75.5 bits (184), Expect = 1e-13,   Method: Composition-based stats.
 Identities = 41/108 (37%), Positives = 58/108 (53%)
 Frame = +2

Query: 121 LELERPLTESQIQVVCKQTLEALNYLHDNKIIHRDLKAGNILFTLDGDIKLADFGVSAKN 180
           L  ER  TE + +    + + AL YLH   II+RDLK  N+L   DG IK+ADFG+  ++
Sbjct: 5   LSHERIFTEERTRFYGAEIISALGYLHSQGIIYRDLKLENLLLDKDGHIKVADFGLCKED 184

Query: 181 TRTIQRRDSFIGTPYWMAPEVVMCETSKDRPYDYKADVWSLGITLIEM 228
               +   +F GTP ++APEV+      D  Y    D W  G+ + EM
Sbjct: 185 ITYGRTTKTFCGTPEYLAPEVL-----DDNDYGRAVDWWGTGVVMYEM 313
>04591
          Length = 1117

 Score = 75.5 bits (184), Expect = 1e-13,   Method: Composition-based stats.
 Identities = 49/163 (30%), Positives = 88/163 (53%), Gaps = 8/163 (4%)
 Frame = -2

Query: 79   EIDILASCDHPNIVKLLDAFY--------YENNLWILIEFCAGGAVDAVMLELERPLTES 130
            EI IL   +H N+V+L +  +        Y++  +++ E+C    +  ++  L    + +
Sbjct: 1071 EIKILQQLEHENVVQLQEICHTQAGPYNRYKSTFYLIFEYCDYD-LAGLLNNLRVKFSLA 895

Query: 131  QIQVVCKQTLEALNYLHDNKIIHRDLKAGNILFTLDGDIKLADFGVSAKNTRTIQRRDSF 190
              + +  Q L  L Y+H  +I+HRD+KA NIL T DG +KLADFG+S    ++ +R  + 
Sbjct: 894  DKKNLMSQLLNGLFYIHTKQILHRDIKAANILLTRDGVLKLADFGLSRPWVKS-KRLTNR 718

Query: 191  IGTPYWMAPEVVMCETSKDRPYDYKADVWSLGITLIEMAEIEP 233
            + T ++  PE+++ E    R Y  + D+W +G  + EM   +P
Sbjct: 717  VVTLWYRPPELLLGE----REYGPEIDMWGVGCIMAEMWSRKP 601
>13066
          Length = 551

 Score = 75.1 bits (183), Expect = 2e-13,   Method: Composition-based stats.
 Identities = 55/175 (31%), Positives = 87/175 (49%), Gaps = 9/175 (5%)
 Frame = +3

Query: 57  NVLAAAKVIDTKSE--EELEDYMV-EIDILASCDHPNIVKLLDAFYYENNLWILIEFCAG 113
           N+  A K+ID +    + +E +   E+D+L   DHP I+++          +I + F   
Sbjct: 51  NIKLACKIIDKEKAPVDFVEKFFPRELDLLTKLDHPYIIQIHSILQRXPKNFIFMRFAER 230

Query: 114 GAVDAVMLELERPLTESQIQVVCKQTLEALNYLHDNKIIHRDLKAGNILFTLDGDIKLAD 173
           G +   + E+   + E Q ++   Q   ALNYLH   + HRDLK  NIL +   ++KLAD
Sbjct: 231 GDLLTYIQEVGF-VKEKQAKIWFYQMTTALNYLHSYDVAHRDLKCENILLSSHFNVKLAD 407

Query: 174 FG-----VSAKNTRTIQRRDSFIGTPYWMAPEVVMCETSKDRPYDYK-ADVWSLG 222
           FG     ++    + + R  ++ G+  + APE+V        PY  K AD WSLG
Sbjct: 408 FGFACACITESGEKYMSR--TYCGSAAYAAPEIVY-----GAPYAPKVADAWSLG 551
>18484
          Length = 635

 Score = 74.7 bits (182), Expect = 2e-13,   Method: Composition-based stats.
 Identities = 36/93 (38%), Positives = 53/93 (56%)
 Frame = +1

Query: 142 ALNYLHDNKIIHRDLKAGNILFTLDGDIKLADFGVSAKNTRTIQRRDSFIGTPYWMAPEV 201
            L +LHD  II+RDLK  N++   +G IK+ADFG+  +         +F GTP ++APE+
Sbjct: 79  GLFFLHDQGIIYRDLKLDNVMLDSEGHIKIADFGMCKEGMTGDATTRTFCGTPDYIAPEI 258

Query: 202 VMCETSKDRPYDYKADVWSLGITLIEMAEIEPP 234
           V+ +     PY    D W+ G+ L EM   +PP
Sbjct: 259 VLYQ-----PYSKSVDWWAYGVLLFEMLAGQPP 342
>09007
          Length = 1440

 Score = 71.6 bits (174), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 66/280 (23%), Positives = 127/280 (45%), Gaps = 18/280 (6%)
 Frame = -1

Query: 40  LGDGAFGKV----YKAQNKETNVLAAAKVIDTKSEEELEDYMVEIDILASCDHPNIVKLL 95
           LG G FG V    + A++ E   +A   +   K  ++ ++++ E  I+   DH NIV++ 
Sbjct: 855 LGQGHFGTVRQAIWTAESGEKVQVAVKCLSKDKIHKDGQEFLKETAIMQMLDHENIVRVY 676

Query: 96  DAFYYEN-NLWILIEFCAGGAVDAVMLELERPLTESQIQVVC---KQTLEALNYLHDNKI 151
                   ++ ++ E     ++   + E+   +  S +  +C   +Q  + ++YL   ++
Sbjct: 675 GVVMDNGADIMLVTELAPMRSLLECVKEVSARVDFS-VPRLCDFSQQVCDGMSYLESKRL 499

Query: 152 IHRDLKAGNILFTLDGDIKLADFGVSA---------KNTRTIQRRDSFIGTPYWMAPEVV 202
           +HRDL A NIL      +K++D GVS          ++ +TI  +++      W AP   
Sbjct: 498 VHRDLAARNILLFSKSKVKISDVGVSGALGAGKEYYQSQQTIHLQNAVA----WCAP--- 340

Query: 203 MCETSKDRPYDYKADVWSLGITLIE-MAEIEPPHHELNPMRVLLKIAKSEPPTLAQPSKW 261
             E+ ++  +   +DVW+ G+ L E       P   LN  +++  +   +   L QP   
Sbjct: 339 --ESFRNLCFSSASDVWAFGVLLWEFFTHGFQPWAGLNGQQIMEAVDAPQSQRLEQPDLC 166

Query: 262 SSNFKDFLRKCLEKNVDARWTTSQLLQHPFVTVDSNKPVR 301
              +   + KC E+    R T SQL    F+T+   +P++
Sbjct: 165 PKEYYAVMLKCWEQEPQRRPTFSQL----FLTLPQIRPIQ 58
>15910
          Length = 1361

 Score = 71.6 bits (174), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 58/161 (36%), Positives = 83/161 (51%), Gaps = 8/161 (4%)
 Frame = +2

Query: 140 LEALNYLHDNKIIHRDLKAGNILF---TLDGDIKLADFGVSAKNTRTIQ---RRDSFIGT 193
           L  + Y+H N ++HRDLK  N+L+   T D  +KLADFG+S    R I+   +  +  GT
Sbjct: 494 LHGVQYIHANGVVHRDLKPENLLYECMTDDSKLKLADFGLS----RIIEPEVQMSTVCGT 661

Query: 194 PYWMAPEVVMCETSKDRPYDYKADVWSLG-ITLIEMAEIEPPHHELNPMRVLLKIAKSEP 252
           P + APEV+     K   Y    D+WS+G I  I +   EP   E N   +  KI K E 
Sbjct: 662 PGYCAPEVL-----KGDKYTPSVDMWSVGVIAYILLCGYEPFFAE-NEFEMYRKIIKGEY 823

Query: 253 PTLAQP-SKWSSNFKDFLRKCLEKNVDARWTTSQLLQHPFV 292
               +  S+ S N KD +RK L  +   R T ++ L+ P+V
Sbjct: 824 KFDEEYWSEISENAKDVVRKLLVIDPKKRLTATEALRLPWV 946
>02638
          Length = 1490

 Score = 69.3 bits (168), Expect = 1e-11,   Method: Composition-based stats.
 Identities = 40/108 (37%), Positives = 57/108 (52%), Gaps = 4/108 (3%)
 Frame = +1

Query: 190 FIGTPYWMAPEVVMCETSKDRPYDYKADVWSLGITLIEMAEIEPP---HHELNPMRVLLK 246
            +GT  +MAPEV+  E+     Y    DVWS+G  +IEM    PP   H   N + ++ K
Sbjct: 16  LLGTIAFMAPEVLRGES-----YGRACDVWSVGCVMIEMCTCRPPWNSHDISNHLALIFK 180

Query: 247 IAKS-EPPTLAQPSKWSSNFKDFLRKCLEKNVDARWTTSQLLQHPFVT 293
           IA S +PP +  P   S   +D + +CLE++ D R +   LL HP  T
Sbjct: 181 IASSVDPPPI--PENMSPPVRDLMLRCLEQDSDFRPSAKDLLMHPLFT 318
>04138
          Length = 800

 Score = 68.6 bits (166), Expect = 2e-11,   Method: Composition-based stats.
 Identities = 42/110 (38%), Positives = 60/110 (54%), Gaps = 3/110 (2%)
 Frame = +1

Query: 127 LTESQIQVVCKQTLEALNYLHDNKIIHRDLKAGNILFTLDGDIKLADFGVS---AKNTRT 183
           L ES+ + +C    E L Y+H NKI+HRD+KA NIL T  G +KLADFG++   + N R 
Sbjct: 7   LPESK-KSIC*AADERLYYIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQ 183

Query: 184 IQRRDSFIGTPYWMAPEVVMCETSKDRPYDYKADVWSLGITLIEMAEIEP 233
             R  + + T ++  PE+++     DR Y    D W  G  + EM    P
Sbjct: 184 PNRYTNRVVTLWYRPPELLL----GDRNYSTAIDQWGAGCIMAEMWTRNP 321
>00715
          Length = 1788

 Score = 68.2 bits (165), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 55/225 (24%), Positives = 100/225 (44%), Gaps = 29/225 (12%)
 Frame = +1

Query: 88  HPNIVKLLDA---FYYENNLWILIEFCAGGAVDAVMLELERPLTESQIQVVCKQTLEALN 144
           H N+V +L A     +E+  W+ +E+     +  ++ + ++ +  S    +  Q    L+
Sbjct: 103 HVNVVSILGATSLHRFEDGAWLAMEYVGPLNLQTILNDHQQDIDSSMRLSLALQMARGLH 282

Query: 145 YLHDNKIIHRDLKAGNILFTLDGDIKLADFGVSAKNTRT--------------------I 184
           YLH   I+H DLK  N L T D  +++ADFG   + T T                    +
Sbjct: 283 YLHSINIVHLDLKPANCLLTRDLKLRIADFGCCHQLTPTGLDMGEREGGMAGNELELTPV 462

Query: 185 Q--RRDSFIGTPYWMAPEVVMCETSKDRPYDYKADVWSLGITLIEMAEIEPPHHELNPMR 242
           Q   ++   GT  + APE++     K      ++DV+SLGITL +M   + P+  +    
Sbjct: 463 QGAWKNELAGTLAYRAPELL-----KGLQPSVRSDVYSLGITLWQMCTRQGPYEGVPAHA 627

Query: 243 VLLKIAKSE----PPTLAQPSKWSSNFKDFLRKCLEKNVDARWTT 283
           V+ ++   +    PP   +   +   F+D   +C  + V+ R T+
Sbjct: 628 VVYQVVSKDLRPCPPPSTEDDPFEVMFRDLYTQCWARRVEDRPTS 762
>21079
          Length = 878

 Score = 66.6 bits (161), Expect = 6e-11,   Method: Composition-based stats.
 Identities = 43/141 (30%), Positives = 70/141 (49%), Gaps = 5/141 (3%)
 Frame = +1

Query: 88  HPNIVKLLDAFYYENNLWILIEFCAGGAVDAVMLELERPLTESQIQVVCKQTLEALNYLH 147
           HP ++ L DAF     + +++EF   G +   ++  +  LTE       +Q    + Y+H
Sbjct: 1   HPKLLMLWDAFEAPRTMVLVMEFVGAGELFERVIRDDFVLTERDCVHFVRQICSGVGYMH 180

Query: 148 DNKIIHRDLKAGNILFTLDGD--IKLADFGVSAKNTRTIQRRDS---FIGTPYWMAPEVV 202
              I+H DLK  N+L   D    IK+ DFG++    R  +  DS     GTP ++APEVV
Sbjct: 181 TQSILHLDLKPENVLCVSDNSNQIKIIDFGLA----RFYKPGDSLQVLFGTPEFIAPEVV 348

Query: 203 MCETSKDRPYDYKADVWSLGI 223
             +       ++  D+WS+G+
Sbjct: 349 NYDE-----INFTTDMWSIGV 396
>12786
          Length = 460

 Score = 66.2 bits (160), Expect = 8e-11,   Method: Composition-based stats.
 Identities = 41/132 (31%), Positives = 66/132 (50%), Gaps = 17/132 (12%)
 Frame = -3

Query: 124 ERPLTESQIQVVCKQTLEALNYLHDNKIIHRDLKAGNILFTLDGDIKLADFGV--SAKNT 181
           E+ L    I+   ++ L A+  LH+  +IH DLK  N +  + G++KL DFG+  + +  
Sbjct: 428 EQGLDRMMIKFYWREMLRAVKALHNEGVIHSDLKPANFML-VAGNLKLIDFGIANTLQQD 252

Query: 182 RTIQRRDSFIGTPYWMAPEVVM--CETSKDRPYD-------------YKADVWSLGITLI 226
           +T   +DS +GTP +M+PE +M  C+ S D   +              ++DVWSLG  L 
Sbjct: 251 KTSVLKDSRVGTPSYMSPEAIMAACDDSADDSMEEDGHRTKPKYKVGVRSDVWSLGCILY 72

Query: 227 EMAEIEPPHHEL 238
            M     P   +
Sbjct: 71  NMVYGRTPFQHI 36
>27405
          Length = 532

 Score = 66.2 bits (160), Expect = 8e-11,   Method: Composition-based stats.
 Identities = 46/181 (25%), Positives = 90/181 (49%), Gaps = 7/181 (3%)
 Frame = -3

Query: 44  AFGKVYKAQNKETNVLAAAKVIDTK------SEEELEDYMVEIDILASCD-HPNIVKLLD 96
            FG+VY  +  +T  + A K +D K       E    +  + + ++++ +  P IV +  
Sbjct: 530 GFGEVYGCRKADTGKMYAMKCLDKKRIKMKGGETLALNERIMLSLVSTGEGSPFIVCMTY 351

Query: 97  AFYYENNLWILIEFCAGGAVDAVMLELERPLTESQIQVVCKQTLEALNYLHDNKIIHRDL 156
           AF     L  +++   GG +    L      TE +++    + +  L ++H   +++RDL
Sbjct: 350 AFQTPEKLCFILDLMNGGDLH-YHLSQHGVFTEKEVRFYAAEVMLGLEHMHSRFVVYRDL 174

Query: 157 KAGNILFTLDGDIKLADFGVSAKNTRTIQRRDSFIGTPYWMAPEVVMCETSKDRPYDYKA 216
           K  NIL   +G ++++D G++   ++  ++  + +GT  +MAPEV+M    K + YD  A
Sbjct: 173 KPANILLDENGHVRISDLGLACDFSK--KKPHASVGTHGYMAPEVLM----KGQAYDSSA 12

Query: 217 D 217
           D
Sbjct: 11  D 9
>01392
          Length = 1806

 Score = 65.9 bits (159), Expect = 1e-10,   Method: Composition-based stats.
 Identities = 57/192 (29%), Positives = 86/192 (44%), Gaps = 26/192 (13%)
 Frame = -1

Query: 127  LTESQIQVVCKQTLEALNYLHDNKIIHRDLKAGNILFTLDGDI---KLADF----GVS-- 177
            L E +  +V +    AL++LH   I HRDLK  NIL     D+   K+ DF    G+S  
Sbjct: 1800 LCEREASLVVRHIARALDFLHSKGIAHRDLKPENILCEHLDDVVPVKICDFDLASGISCD 1621

Query: 178  AKNTRTIQRRDSFIGTPYWMAPEVVMCETSKDRPYDYKADVWSLGITLIEMAEIEPPH-- 235
               T+T +     +G+  +MAPEVV         YD + D+WSLGI L  M    PP   
Sbjct: 1620 GDGTKTPELLTP-VGSAEYMAPEVVDAWVGDSFSYDKRCDLWSLGIILYIMLCGYPPFYG 1444

Query: 236  --------------HELNPMRVLLKIAKSEPPTLAQP-SKWSSNFKDFLRKCLEKNVDAR 280
                          H+   M +   I        +Q  +  SS+ KD +R  L +    R
Sbjct: 1443 QCGEDCGWNRGEACHDCQDM-LFNSIQDGHYKFPSQEWTSISSSAKDLIRHLLVREPRKR 1267

Query: 281  WTTSQLLQHPFV 292
            ++ + +L+HP++
Sbjct: 1266 YSAADVLKHPWI 1231
>04852
          Length = 1462

 Score = 65.5 bits (158), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 68/272 (25%), Positives = 108/272 (39%), Gaps = 28/272 (10%)
 Frame = +1

Query: 46  GKVYKAQNKETNVLAAAKVIDTKSEEELEDYMVEIDILASC----DHPNIVKLLDAFYYE 101
           G+V KA      +L   + I T  EE+  D++ E+ ++ +      H NIV  L      
Sbjct: 4   GRVPKASTVAVKML---RDIVTAVEEQ--DFVQELQVMKAVKKMGSHINIVNFLGCCTQG 168

Query: 102 NNLWILIEFCAGGAV--------DAV-----MLELERP-----------LTESQIQVVCK 137
             LW+++EF   G +        D +      +  + P           +    +     
Sbjct: 169 GPLWVIVEFAKNGNLRDFLESCRDGINGYGKFVSPQDPGWYTKTPGGHVIRRKNLLSYAF 348

Query: 138 QTLEALNYLHDNKIIHRDLKAGNILFTLDGDIKLADFGVSAKNTRTIQRRDSFIGTPYWM 197
           Q    + +L   K IHRDL A N+L T +  +K+ADFG+S       +R    +    WM
Sbjct: 349 QIARGMEFLASRKCIHRDLAARNVLVTEEHVLKIADFGLSRTGDYYKKRSGGRLPVK-WM 525

Query: 198 APEVVMCETSKDRPYDYKADVWSLGITLIEMAEIEPPHHELNPMRVLLKIAKSEPPTLAQ 257
           APE +      D  Y  K+DVWS G+ L E+  +    +   P   L      +   + +
Sbjct: 526 APEALF-----DMRYTTKSDVWSFGVVLWEIFSLGGMPYASIPNEELYSKLLDDAYRMPR 690

Query: 258 PSKWSSNFKDFLRKCLEKNVDARWTTSQLLQH 289
           P   S N    + +C       R   SQL+ H
Sbjct: 691 PELASGNLYAIMERCWLNRPSDRPEFSQLVGH 786
>26560
          Length = 398

 Score = 65.1 bits (157), Expect = 2e-10,   Method: Composition-based stats.
 Identities = 33/113 (29%), Positives = 63/113 (55%)
 Frame = -1

Query: 127 LTESQIQVVCKQTLEALNYLHDNKIIHRDLKAGNILFTLDGDIKLADFGVSAKNTRTIQR 186
            TE +++    + +  L ++H   +++RDLK  NIL   +G ++++D G++   ++  +R
Sbjct: 365 FTEKEVRFYAAEVMLGLEHMHSRFVVYRDLKPANILLDENGHVRISDLGLACDFSK--KR 192

Query: 187 RDSFIGTPYWMAPEVVMCETSKDRPYDYKADVWSLGITLIEMAEIEPPHHELN 239
             + +GT  +MAPEV+M    K + YD  AD +S G  L ++ +   P  + N
Sbjct: 191 PHASVGTHGYMAPEVLM----KGQSYDSSADWFSFGCMLYKLLKGHSPFRQHN 45
>21808
          Length = 1011

 Score = 63.9 bits (154), Expect = 4e-10,   Method: Composition-based stats.
 Identities = 44/159 (27%), Positives = 76/159 (47%), Gaps = 5/159 (3%)
 Frame = +1

Query: 74  EDYMVEIDILASCDHPNIVKLLDAFYYENNLWILIEFCAGGAVDAVMLELERPLTESQIQ 133
           +D++ E  I+    HP +++L      ++ ++I+ E    G++   +    R L    + 
Sbjct: 67  KDFLAEAQIMKKLRHPKLIQLYAVCTQDDPIFIITELMKNGSLLEFLQGKGRVLKLPALI 246

Query: 134 VVCKQTLEALNYLHDNKIIHRDLKAGNILFTLDGDIKLADFGVSAKNTRTIQRR--DSFI 191
            +  Q    + YL     IHRDL A NIL + +  +K+ADFG++    R I+    ++ +
Sbjct: 247 DIGAQIACGMAYLESQNYIHRDLAARNILVSDNNTVKIADFGLA----RVIKEDEYEARV 414

Query: 192 GTPY---WMAPEVVMCETSKDRPYDYKADVWSLGITLIE 227
           G  +   W AP     E +    +  K+DVWS GI L E
Sbjct: 415 GARFPIKWTAP-----EAANYNRFTIKSDVWSFGILLTE 516
>21210
          Length = 518

 Score = 63.5 bits (153), Expect = 4e-10,   Method: Composition-based stats.
 Identities = 39/108 (36%), Positives = 60/108 (55%), Gaps = 1/108 (0%)
 Frame = +3

Query: 194 PYWMAPEVVMCETSKDRPYDYKADVWSLGITLIEMAEIEPPHHE-LNPMRVLLKIAKSEP 252
           PY MAPE +    S    YD ++DVWSLGITL+E+A    P+ + ++    L ++ +   
Sbjct: 15  PY-MAPERIDPRASS-HGYDVRSDVWSLGITLMELATGRFPYRKWVSIFDQLQQVVRGVA 188

Query: 253 PTLAQPSKWSSNFKDFLRKCLEKNVDARWTTSQLLQHPFVTVDSNKPV 300
           P L     +S +F +F+ KCL K+   R   ++LL HPFV +   + V
Sbjct: 189 PCLPHDGAFSHDFVNFVNKCLTKDEKQRPKYNKLLAHPFVRLYEEQEV 332
>17975
          Length = 449

 Score = 63.5 bits (153), Expect = 6e-10,   Method: Composition-based stats.
 Identities = 43/136 (31%), Positives = 71/136 (52%), Gaps = 3/136 (2%)
 Frame = +3

Query: 45  FGKVYKAQNKETNVLAAAKVID-TKSEEELEDYMV-EIDILASCDHPNIVKLLDAFYYEN 102
           F  V  A++  T    A KVID TK +E    ++  E+  +    HPN+V+L +    + 
Sbjct: 6   FAVVKLARHVFTGEKVAVKVIDKTKLDEVSRSHLFQEVRCMKLVQHPNVVRLYEVIDTQT 185

Query: 103 NLWILIEFCAGGAVDAVMLELERPLTESQIQVVCKQTLEALNYLHDNKIIHRDLKAGNIL 162
            L++++E   GG +   ++     L E   +   +Q +EA++Y H   ++HRDLK  N++
Sbjct: 186 KLYLILELGDGGDMYDYIMRHSGGLEEKLAKRYFRQIVEAISYCHKLHVVHRDLKPENVV 365

Query: 163 -FTLDGDIKLADFGVS 177
            F   G +KL DFG S
Sbjct: 366 FFEKPGLVKLTDFGFS 413
>27546
          Length = 426

 Score = 63.2 bits (152), Expect = 7e-10,   Method: Composition-based stats.
 Identities = 34/99 (34%), Positives = 57/99 (57%)
 Frame = -1

Query: 79  EIDILASCDHPNIVKLLDAFYYENNLWILIEFCAGGAVDAVMLELERPLTESQIQVVCKQ 138
           E++IL   DHPNI+++         ++I + +   G + +  ++   P+ E+Q +V   Q
Sbjct: 330 ELEILTRLDHPNIIQIHSILQRGPKIFIFMRYAEKGDMLS-HIKKTGPIDEAQTKVWFFQ 154

Query: 139 TLEALNYLHDNKIIHRDLKAGNILFTLDGDIKLADFGVS 177
             +AL YLH + I HRDLK  NIL +   ++K+ADFG +
Sbjct: 153 MAKALQYLHSHDIAHRDLKCENILLSKRLNVKIADFGFA 37
>19301
          Length = 712

 Score = 62.8 bits (151), Expect = 8e-10,   Method: Compositional matrix adjust.
 Identities = 50/153 (32%), Positives = 72/153 (47%), Gaps = 9/153 (5%)
 Frame = +2

Query: 34  WEIIGE-------LGDGAFGKVYKAQNKETNVLAAAKVIDTKSEEELEDYMVEIDI--LA 84
           WEI  E       LG GA G V+  +     V A  KV D K          E DI  L 
Sbjct: 290 WEIPFESITDLEWLGSGAQGAVFLGKLCAEEV-AVKKVRDIK----------ETDIRNLR 436

Query: 85  SCDHPNIVKLLDAFYYENNLWILIEFCAGGAVDAVMLELERPLTESQIQVVCKQTLEALN 144
             +HPNI+             I++E+C  G +  V+ +  + +  + +    KQ    +N
Sbjct: 437 KLNHPNIISFKGVCTQAPCYCIIMEYCPYGQLYEVLRD-GKEIPPALVLDWSKQIASGMN 613

Query: 145 YLHDNKIIHRDLKAGNILFTLDGDIKLADFGVS 177
           YLH +KIIHRDLK+ N+L   +  +K++DFG S
Sbjct: 614 YLHSHKIIHRDLKSPNVLVAKNDVVKISDFGTS 712
>11780
          Length = 1713

 Score = 62.8 bits (151), Expect = 8e-10,   Method: Compositional matrix adjust.
 Identities = 53/169 (31%), Positives = 82/169 (48%), Gaps = 3/169 (1%)
 Frame = +3

Query: 37  IGE-LGDGAFGKVYKAQNKETNVLAAAKVIDTKSEEELEDYMVEIDILASCDHPNIVKLL 95
           IGE +G G FG VYK   +   V  A K +  K   E + ++ E  ++ S  H N+V+L+
Sbjct: 609 IGEAIGKGDFGDVYKGMYRGQPV--AIKQLKDKDRGE-QSFLQEASVMTSLRHDNLVRLI 779

Query: 96  DAFYYENNLWILIEFCAGGAVDAVMLELERPLTESQIQV-VCKQTLEALNYLHDNKIIHR 154
                E  ++++ EF   G +   +    R +   + Q+     T  A+ YL   +++HR
Sbjct: 780 GVVLGET-IFLVTEFMGKGNLVEYLRSRGRSVITKKDQINFATDTCAAMEYLESKRLVHR 956

Query: 155 DLKAGNILFTLDGDIKLADFGVSAKNTRTIQRRDSFIGTPY-WMAPEVV 202
           DL A N+L   DG  K++DFG+ AK     Q    F   P  W APE +
Sbjct: 957 DLAARNVLVHDDGKAKVSDFGL-AKFGDFSQTSVKF---PIKWTAPEAL 1091
>01966
          Length = 1735

 Score = 61.6 bits (148), Expect = 2e-09,   Method: Composition-based stats.
 Identities = 46/154 (29%), Positives = 77/154 (50%), Gaps = 9/154 (5%)
 Frame = -1

Query: 59   LAAAKVIDTKSEEELEDYMV-EIDILASCDHPNIVKLLDAFYYENNLWILIEFCAGGAVD 117
            LA  K+    SE+ +    + EI +L    H NIV L D    +  L+++ EF +   +D
Sbjct: 1627 LAMKKIRLRGSEDGVPSSAIREIAMLRELRHTNIVCLEDVIMEDERLFLVFEFLS---MD 1457

Query: 118  AVM--------LELERPLTESQIQVVCKQTLEALNYLHDNKIIHRDLKAGNILFTLDGDI 169
              M        + L+R L +S +     Q +  +N+ H  +I+HRDLK  N+L    G I
Sbjct: 1456 LKMYIDKFPEGVVLDRRLVKSYV----FQIVTGINFCHQRRIVHRDLKPQNLLINHTGAI 1289

Query: 170  KLADFGVSAKNTRTIQRRDSFIGTPYWMAPEVVM 203
            K+ADFG++      ++     + T ++ APE++M
Sbjct: 1288 KIADFGMARTFALPVRAYTHEVVTLWYRAPEILM 1187
>07940
          Length = 1336

 Score = 61.6 bits (148), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 40/113 (35%), Positives = 58/113 (51%), Gaps = 6/113 (5%)
 Frame = -3

Query: 122 ELERPLTESQIQVVCKQTLEALNYLHDNKIIHRDLKAGNILFTLDGDIKLADFGVSAKNT 181
           ++ + LT   +     Q    + YL   + IHRDL A N+L   +  +K+ADFG+    T
Sbjct: 371 DMLKMLTPKDLISYAYQVARGMEYLASKQCIHRDLAARNVLVAEEYVLKIADFGL----T 204

Query: 182 RTIQRRDSFIGT-----PY-WMAPEVVMCETSKDRPYDYKADVWSLGITLIEM 228
           R +Q+ D +  T     P  WMAPE +      DR Y  K+DVWS G+ L E+
Sbjct: 203 RNLQQFDYYRKTTDGRLPVKWMAPEALF-----DRKYTSKSDVWSYGVLLWEI 60

 Score = 35.4 bits (80), Expect = 0.13,   Method: Compositional matrix adjust.
 Identities = 30/102 (29%), Positives = 53/102 (51%), Gaps = 14/102 (13%)
 Frame = -3

Query: 27  DLNPEEFWE------IIGE-LGDGAFGKVYKAQN----KETN-VLAAAKVI-DTKSEEEL 73
           DL  +  WE      ++G+ LG+GAFG V K +     K+ N V  A K++ +  ++ E+
Sbjct: 878 DLPLDAKWEFPRERLVLGDRLGEGAFGLVMKGEAMGIFKDNNSVTVAVKMLKEDATDREM 699

Query: 74  EDYMVEIDILASCD-HPNIVKLLDAFYYENNLWILIEFCAGG 114
            D + E++++     H NI+ LL        L++++EF   G
Sbjct: 698 MDLIREMEMMKVIGKHKNIINLLGCCTQRGALYVIVEFAPHG 573
>21433
          Length = 590

 Score = 54.3 bits (129), Expect(2) = 8e-09,   Method: Composition-based stats.
 Identities = 39/97 (40%), Positives = 53/97 (54%)
 Frame = +2

Query: 138 QTLEALNYLHDNKIIHRDLKAGNILFTLDGDIKLADFGVSAKNTRTIQRRDSFIGTPYWM 197
           Q   AL Y H  K+IHRD+K  N+L  L GD+K+ADFG S     +  RR +  GT  ++
Sbjct: 191 QLSSALEYCHYRKVIHRDIKPENLLLGLKGDLKIADFGWSVHAPSS--RRTTMCGTLDYL 364

Query: 198 APEVVMCETSKDRPYDYKADVWSLGITLIEMAEIEPP 234
            PE+V  +T     +D   D+WSLG+   E     PP
Sbjct: 365 PPEMVEGKT-----HDENVDLWSLGVLCYEFLVGTPP 460

 Score = 25.0 bits (53), Expect(2) = 8e-09,   Method: Composition-based stats.
 Identities = 10/36 (27%), Positives = 22/36 (61%)
 Frame = +3

Query: 79  EIDILASCDHPNIVKLLDAFYYENNLWILIEFCAGG 114
           EI+I +   H NI+++   F+ +  +++++EF   G
Sbjct: 18  EIEIQSHLRHDNILRMFGYFHDKTRVYLILEFAPKG 125
>14116
          Length = 1017

 Score = 59.7 bits (143), Expect = 8e-09,   Method: Composition-based stats.
 Identities = 53/211 (25%), Positives = 96/211 (45%), Gaps = 14/211 (6%)
 Frame = -1

Query: 32  EFWEIIGELGDGAFGKVYKA----QNKETNVLAAAKVI--DTKSEEELEDYMVEIDILAS 85
           EF  +  E+G G FG V +       ++ ++L A K +  +   E EL+ ++ E  I+  
Sbjct: 636 EFLTMGEEIGKGNFGCVKRGFLTLPEQKGDILVAVKTLHNNNPREIELQSFLQEALIMKD 457

Query: 86  CDHPNIVKLLDAFYYENNL-WILIEFCAGGAVDAVMLELERPLTESQIQVVCKQTLEALN 144
             H N++ L+      +++  +++ F   G +   + + +   T   + +        ++
Sbjct: 456 FHHSNVLTLIGICLNLDDMPLVVLPFMKHGDLLTYIRDDQHQPTIKDLIMYGVDIARGMD 277

Query: 145 YLHDNKIIHRDLKAGNILFTLDGDIKLADFGVSAKNTRTIQRRDSFIGTP-------YWM 197
           YL   K +HRDL A N +   D  +K+ADFG++    R I  ++ +            WM
Sbjct: 276 YLAGLKFVHRDLAARNCMLDEDFHVKVADFGLA----RDIYEKEYYSSENKKAKLPVKWM 109

Query: 198 APEVVMCETSKDRPYDYKADVWSLGITLIEM 228
           A      E+ +   YD K DVWS G+ L E+
Sbjct: 108 A-----LESLEKGNYDSKTDVWSYGVVLWEL 31
>28638
          Length = 1458

 Score = 58.9 bits (141), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 40/106 (37%), Positives = 54/106 (50%), Gaps = 4/106 (3%)
 Frame = -1

Query: 137 KQTLEALNYLH--DNKIIHRDLKAGNILFTLD--GDIKLADFGVSAKNTRTIQRRDSFIG 192
           +Q   AL +L   +  IIH DLK  NIL        IK+ DFG S +     QR   +I 
Sbjct: 816 QQLCTALLFLATPEMNIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLG---QRIYQYIQ 646

Query: 193 TPYWMAPEVVMCETSKDRPYDYKADVWSLGITLIEMAEIEPPHHEL 238
           + ++ +PEV++       PYD   D+WSLG  L+EM   EPP   L
Sbjct: 645 SRFYRSPEVLL-----GVPYDLAIDMWSLGCILVEMHTGEPPLCRL 523
>07291
          Length = 833

 Score = 57.0 bits (136), Expect = 5e-08,   Method: Compositional matrix adjust.
 Identities = 33/107 (30%), Positives = 57/107 (53%), Gaps = 5/107 (4%)
 Frame = +1

Query: 127 LTESQIQVVCKQTLEALNYLHDNKIIHRDLKAGNILFTLDGDIKLADFGVSAKNTRTIQR 186
           LT  Q+    +Q  + + YL + K++HR+L A N + T DG ++L+D+GV+   +   Q 
Sbjct: 40  LTVVQLLDFGRQIADGMAYLQEVKVVHRNLAARNCIVTEDGRLQLSDYGVTG--SLFPQS 213

Query: 187 RDSFIGTPY-----WMAPEVVMCETSKDRPYDYKADVWSLGITLIEM 228
             +   +P      WMAPE +      +  +  K+DVW+ G+ L E+
Sbjct: 214 YYTADDSPARDLVKWMAPETI-----DNFHFSSKSDVWAFGVVLWEL 339
>16708
          Length = 1397

 Score = 55.1 bits (131), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 68/280 (24%), Positives = 105/280 (37%), Gaps = 35/280 (12%)
 Frame = -1

Query: 36   IIGELGDGAFGKVYKAQNKETNVLAAAK--VIDTKSEEELEDYMVEIDILASCDHPNIVK 93
            I+  LG G FGKVY+A+   T+  AA K  ++   S +E+E                + +
Sbjct: 1391 ILQVLGKGVFGKVYEARLLSTHEKAALKTSILCHHSLDEVEA---------------LGR 1257

Query: 94   LLDAFYYENNL--W----------ILIEFCAGGAVDAVMLEL---ERPLTESQIQVVC-- 136
            +   FY       W          IL+ F   G +  V       E P+  S   +VC  
Sbjct: 1256 IEGGFYLAQMFGAWVTCLPFPKMNILLHFYEMGPLCNVYAHYKNKEMPIRWSNPAMVCCI 1077

Query: 137  -KQTLEALNYLHDNKIIHRDLKAGNILFTLDGDIKLADFGVS-----------AKNTRTI 184
              Q + AL ++H+  ++H D+KA N+L    G+ KL D+G++             ++   
Sbjct: 1076 AGQXVCALEHIHELGVVHMDVKADNVLVDAHGNCKLTDYGIAQLYKVYPAPTETHSSGCT 897

Query: 185  QRRDSFIGTPYWMAPEVVMCETSKDRPYDYKADVWSLGITLIEMAEIEPPHHELNPMRVL 244
             +R  +   P  M P     E       DY    + LG  L  +              VL
Sbjct: 896  NKRTFYTRPPATMTPSERFSEEGDGIGTDY----FRLGQMLWTLTG-----------AVL 762

Query: 245  LKIAKSEPPTLA----QPSKWSSNFKDFLRKCLEKNVDAR 280
            L +  S PP L      P    S   DF+ K    + + R
Sbjct: 761  LHVWVSRPPKLPDWCRTPESELSGMSDFIEKLCHGDPNMR 642
>12672
          Length = 773

 Score = 54.7 bits (130), Expect = 2e-07,   Method: Composition-based stats.
 Identities = 34/98 (34%), Positives = 52/98 (53%), Gaps = 4/98 (4%)
 Frame = +3

Query: 135 VCKQTLEALNYLHDNKIIHRDLKAGNILFTLDGDIKLADFG--VSAKN--TRTIQRRDSF 190
           + K T   + YL+DN  +HRD+K  NIL   +   K+ DF   VSA +   +T+Q     
Sbjct: 6   IVKGTASGIQYLNDNGHVHRDIKTANILLDSEYTAKVGDFATVVSAPSGEGKTVQNASVV 185

Query: 191 IGTPYWMAPEVVMCETSKDRPYDYKADVWSLGITLIEM 228
           IGT  ++APE +  + S       K D +S G+ L+E+
Sbjct: 186 IGTAAYLAPEAIHFDVST------KLDSYSFGVVLLEV 281
>18996
          Length = 491

 Score = 50.1 bits (118), Expect = 6e-06,   Method: Composition-based stats.
 Identities = 50/148 (33%), Positives = 71/148 (47%), Gaps = 11/148 (7%)
 Frame = +2

Query: 152 IHRDLKAGNILFTLDGDIKLADFGVSAKNTRT-----IQRRDSFIGTPYWMAPEVVMCET 206
           IHRDL A NIL      +K++DFG++           I +RD  I    W +PE +  ET
Sbjct: 2   IHRDLAARNILVDRSC-VKISDFGLAQFANADGYYYGISQRDIPIK---WYSPEAI--ET 163

Query: 207 SKDRPYDYKADVWSLGITLIEM---AEIEP--PHHELNPMRVLLKIAKSEPPTLAQPSKW 261
            K   Y   +DVWS G+TL EM    EI    P H+L     L ++ K E   L +P   
Sbjct: 164 CKFSSY---SDVWSYGVTLFEMFSRGEIPNLLPGHDLTQEEFLNRLRKGE--RLPKPELC 328

Query: 262 SS-NFKDFLRKCLEKNVDARWTTSQLLQ 288
           S   + + +R C  +   +R T  Q++Q
Sbjct: 329 SDFVYSELMRPCWHEMPKSRPTFHQIIQ 412
>14477
          Length = 493

 Score = 49.7 bits (117), Expect = 6e-06,   Method: Compositional matrix adjust.
 Identities = 50/169 (29%), Positives = 81/169 (47%), Gaps = 7/169 (4%)
 Frame = -1

Query: 39  ELGDGAFGKVYKAQNK--ETNVLAAAKVI-----DTKSEEELEDYMVEIDILASCDHPNI 91
           +LG G FG V K   +  +  +  A KV+     D   + EL   + E +++   DH +I
Sbjct: 469 KLGAGNFGSVMKGVCRLDDREIPVAIKVLKNADLDPSVQSEL---IKEAEVMKKMDHMHI 299

Query: 92  VKLLDAFYYENNLWILIEFCAGGAVDAVMLELERPLTESQIQVVCKQTLEALNYLHDNKI 151
           V+L+     E  + +L E    G ++   L   + L    I  +  Q  + + YL  NK 
Sbjct: 298 VRLIGLCEGETMMLVL-ELAKLGPLNK-FLPKNKHLPLWNILELMWQVSQGMEYLEANKF 125

Query: 152 IHRDLKAGNILFTLDGDIKLADFGVSAKNTRTIQRRDSFIGTPYWMAPE 200
           +HRDL A NIL   +   K++DFG+S    +T+ R ++     Y+MA E
Sbjct: 124 VHRDLAARNILLCDEHFAKISDFGMS----KTLSRENN-----YYMAQE 5
>26711
          Length = 405

 Score = 48.9 bits (115), Expect = 1e-05,   Method: Composition-based stats.
 Identities = 29/93 (31%), Positives = 51/93 (54%), Gaps = 4/93 (4%)
 Frame = -2

Query: 135 VCKQTLEALNYLHDNKIIHRDLKAGNILFTLD--GDIKLADFGVSAKNTRTIQRRDSFI- 191
           V KQ L+ L ++H   ++H DLK  N+L + D    ++L DFG++ K       +++F+ 
Sbjct: 401 VVKQVLDILQHVHAQGVVHMDLKPSNLLLSGDKLDSVQLIDFGLARK---LYPPQETFLN 231

Query: 192 -GTPYWMAPEVVMCETSKDRPYDYKADVWSLGI 223
            GTP + +PE +       +P    +DVW +G+
Sbjct: 230 HGTPGFTSPEAL-----DVKPISTASDVWGVGV 147
>22005
          Length = 873

 Score = 48.1 bits (113), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 60/251 (23%), Positives = 99/251 (39%), Gaps = 61/251 (24%)
 Frame = +1

Query: 39  ELGDGAFGKVYKAQNKETNVLAAA-----------KVIDTKSEEELE-DYMVEIDILASC 86
           ++G GAFG+V K +      L              K++   + E+L+ D+  E  ++A  
Sbjct: 4   DIGQGAFGRVSKLKFLGLASLVGELIPEKRP*LL*KMLKEDASEDLQSDFEREASLMADF 183

Query: 87  DHPNIVKLLDAFYYENNLWILIEFCAGGAVDAVML-----ELERPLTESQIQVV------ 135
           DHPNIVKLL        + +L EF + G ++  +          P++ SQ  VV      
Sbjct: 184 DHPNIVKLLGVCAIGKPMCLLFEFMSKGDLNDFLRLCSPENYNLPVSRSQNLVVDLEDGL 363

Query: 136 -------------------CKQTLE-------------ALNYLHDNKIIHRDLKAGNILF 163
                              C   L               + YL     +HRDL A   + 
Sbjct: 364 RVEVEAEECEKDTQSEDRDCSGMLXTKDQLYISQQISAGMAYLAQKDYVHRDL-ATRTVX 540

Query: 164 TLDGDIKLADFGVSAKNTRTIQRRDSFIGT-----PY-WMAPEVVMCETSKDRPYDYKAD 217
           +      ++DFG++    R++   D + G+     P  WM  E ++   SK   +  ++D
Sbjct: 541 SRTT*S*ISDFGLA----RSVHSVDYYRGSEQDAIPIRWMPLEAIL--YSK---FSTQSD 693

Query: 218 VWSLGITLIEM 228
           VWS G+ L E+
Sbjct: 694 VWSFGVVLWEI 726
>03508
          Length = 1463

 Score = 48.1 bits (113), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 28/108 (25%), Positives = 56/108 (51%), Gaps = 1/108 (0%)
 Frame = +1

Query: 122 ELERPLTESQIQVVCKQTLEALNYLHDNKIIHRDLKAGNILFTLDGD-IKLADFGVSAKN 180
           +L +  T+  I+    + ++AL++ H   I+HRD+K  N++   +   ++L D+G+ A+ 
Sbjct: 847 QLYQTFTDYDIRFYLYELMKALDFCHSMGIMHRDVKPHNVMIDHENKKLRLIDWGL-AEF 1023

Query: 181 TRTIQRRDSFIGTPYWMAPEVVMCETSKDRPYDYKADVWSLGITLIEM 228
                  +  + + Y+  PE+++      + YDY  D+WSLG     M
Sbjct: 1024YHPGMEYNVRVASRYFKGPELLL----DYQMYDYSLDMWSLGCMFASM 1155
>17253
          Length = 483

 Score = 47.0 bits (110), Expect = 4e-05,   Method: Composition-based stats.
 Identities = 32/127 (25%), Positives = 58/127 (45%), Gaps = 13/127 (10%)
 Frame = -1

Query: 66  DTKSEEELEDYMVEIDILASCD-HPNIVKLLDAFYYENNLWILIEFCAGGAVDAVMLELE 124
           +  ++ E  +++ E+ I+     HPN+V  +      +   IL+EFC  G + +  L   
Sbjct: 438 EAATDAEKSEFLRELSIMRKLPRHPNVVSFMGCCTMSDPALILMEFCCHGDLLS-FLRKR 262

Query: 125 RP------------LTESQIQVVCKQTLEALNYLHDNKIIHRDLKAGNILFTLDGDIKLA 172
           RP            LT              + ++ +NKI+HRD+ A N+L +     K++
Sbjct: 261 RPDRTVFLTSTANDLTARDFFSFALHVARGMAHVANNKIVHRDVAARNVLISERNVCKVS 82

Query: 173 DFGVSAK 179
           DFG+S +
Sbjct: 81  DFGLSRR 61
>07833
          Length = 1504

 Score = 46.6 bits (109), Expect = 6e-05,   Method: Composition-based stats.
 Identities = 56/220 (25%), Positives = 92/220 (41%), Gaps = 14/220 (6%)
 Frame = -3

Query: 75   DYMVEIDILASCDHPNIVKLLDAFYYENNLWILIEFCAGGAVDAVMLELERPLTESQIQV 134
            D+M E   L   +HPN++ +L       NL ++ +F   G++   +        ES I V
Sbjct: 1481 DFMEEFPRLRIFNHPNVLPVLACCNQPPNLVLISQFMPFGSLYNTL------HGESGIVV 1320

Query: 135  VCKQTLE-ALNYLHDNKIIHR-DLKAGNILFT---------LDGDIKLADFGVSAKNTRT 183
               Q+L  A++     + +H  +    N L T         L   I +AD+  S      
Sbjct: 1319 DQNQSLRFAMDIARGMEFLHSMEPTIPNFLLTSKHVMIDEDLTARINMADYCFSFHEKGK 1140

Query: 184  IQRRDSFIGTPYWMAPEVVMCETSKDRPYDYK---ADVWSLGITLIEMAEIEPPHHELNP 240
            +        +P WMAPE +     + RP D     AD+WS  I + E+   E P  EL+ 
Sbjct: 1139 VY-------SPAWMAPEAL-----QRRPDDINTRAADMWSFAILMWELETREVPFAELSS 996

Query: 241  MRVLLKIAKSEPPTLAQPSKWSSNFKDFLRKCLEKNVDAR 280
            M V +K+A  E   ++ P   S +    ++ C+ +    R
Sbjct: 995  MEVGMKVA-LEGLRISIPPGISLHMSRLIKICMNEEPGKR 879
>26009
          Length = 886

 Score = 32.3 bits (72), Expect(2) = 1e-04,   Method: Compositional matrix adjust.
 Identities = 20/83 (24%), Positives = 40/83 (48%), Gaps = 1/83 (1%)
 Frame = +2

Query: 28  LNPEEFWEIIGELGDGAFGKVYKAQNKETNVLAAAKVIDTKSEEELEDYMVEIDI-LASC 86
           L+  E +++  ELG G +GKV  A+ + T    A K++  KS  +L ++  E  +     
Sbjct: 404 LSLREHYDVCKELGRGTYGKVVLARCRHTGTQVALKLL-PKSCTKLREFQREFQLSYFLS 580

Query: 87  DHPNIVKLLDAFYYENNLWILIE 109
            H NI+   +  +   + ++  +
Sbjct: 581 PHANIIDTYNVAFQTRSSYVFAQ 649

 Score = 32.3 bits (72), Expect(2) = 1e-04,   Method: Composition-based stats.
 Identities = 12/32 (37%), Positives = 23/32 (71%)
 Frame = +3

Query: 131 QIQVVCKQTLEALNYLHDNKIIHRDLKAGNIL 162
           + + V KQ + AL+++H  +++HRD+K  N+L
Sbjct: 714 EAKSVMKQLVSALDFMHSKQLVHRDIKPENVL 809
>28157
          Length = 400

 Score = 45.1 bits (105), Expect = 2e-04,   Method: Composition-based stats.
 Identities = 36/116 (31%), Positives = 60/116 (51%), Gaps = 6/116 (5%)
 Frame = +3

Query: 68  KSEEELEDYMVEIDILASCDHPNIVKLLDAFYYENNLWILIEFCAGGAVDAVMLEL--ER 125
           +SE+E + +M E+  L+   HPNIV L  A   ++ + +++E+  GG++  V+     + 
Sbjct: 27  ESEQEKKSFMQELKQLSRVSHPNIVCLYGAC-RDHPVCLVMEYAEGGSLYNVLHGSGPQP 203

Query: 126 PLTESQIQVVCKQTLEALNYLHDNK---IIHRDLKAGNILFTLDG-DIKLADFGVS 177
             T +       Q    + YLH  K   +IHRDLK  N+L    G  +K+ DFG +
Sbjct: 204 QYTAAHAMNWLLQCALGVEYLHGMKPKALIHRDLKPPNLLLIQCGTKLKICDFGTA 371
>20640
          Length = 1492

 Score = 44.3 bits (103), Expect = 3e-04,   Method: Composition-based stats.
 Identities = 34/136 (25%), Positives = 62/136 (45%), Gaps = 7/136 (5%)
 Frame = +1

Query: 152 IHRDLKAGNILFTLDGDIKLADFGVSAKNTRTIQRRDSFIGTPY------WMAPEVVMCE 205
           +HRDL   N L   D  +K++DFG++    R++   D + G+ +      WM  E ++  
Sbjct: 10  VHRDLATRNCLVGHDLVVKISDFGLA----RSVHSVDYYRGSEHDAIPIRWMPLEAILYN 177

Query: 206 TSKDRPYDYKADVWSLGITLIEM-AEIEPPHHELNPMRVLLKIAKSEPPTLAQPSKWSSN 264
                 +  ++DVWS G+ L E+ A    P++ L    V+  +   E   LA P +    
Sbjct: 178 K-----FSTQSDVWSFGVVLWEIFAFALQPYYGLTHEEVVRFV--KEGKVLACPERTPPP 336

Query: 265 FKDFLRKCLEKNVDAR 280
             + +++C  +    R
Sbjct: 337 MYELMKQCWHRRPATR 384
>36481
          Length = 806

 Score = 43.9 bits (102), Expect = 4e-04,   Method: Composition-based stats.
 Identities = 35/129 (27%), Positives = 59/129 (45%), Gaps = 6/129 (4%)
 Frame = +2

Query: 41  GDGAFGKVYKAQNKETNVLAAAKVIDTKSEEELEDYMVEIDILASCDHPN------IVKL 94
           G+G FGKV + ++       A K+I    ++  E   +EI++L      +       V++
Sbjct: 389 GEGTFGKVVQCKDLLKGDDIALKIIKN-VDKYREAAKLEINVLEKLREKDPHAKHMCVQM 565

Query: 95  LDAFYYENNLWILIEFCAGGAVDAVMLELERPLTESQIQVVCKQTLEALNYLHDNKIIHR 154
           LD F Y  ++ I          D +           Q++ +  Q   A+N+LH+N++ H 
Sbjct: 566 LDWFDYHGHVCISFHMLGLSVFDFLKDNSYGAYPIEQVRHISYQLCYAVNFLHENQLTHT 745

Query: 155 DLKAGNILF 163
           DLK  NILF
Sbjct: 746 DLKPENILF 772
>11185
          Length = 473

 Score = 43.9 bits (102), Expect = 5e-04,   Method: Composition-based stats.
 Identities = 44/173 (25%), Positives = 67/173 (38%), Gaps = 23/173 (13%)
 Frame = +1

Query: 142 ALNYLHDNKIIHRDLKAGNILFTLDGDIKLADFGVS----------------AKNTRTIQ 185
            L+Y+H   I+  DL+   +L    G +K ADFG+S                A +   IQ
Sbjct: 37  GLHYIHSLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEAGDQWNIQ 216

Query: 186 RRDSFI------GTPYWMAPEVVM-CETSKDRPYDYKADVWSLGITLIEMAEIEPPHHEL 238
             +  +      G+P +MAPEV    E S        +D+W+LG    EM          
Sbjct: 217 SAEEMMKQVPTSGSPTYMAPEVFQGAEPS------IMSDLWALGCVFYEMF--------- 351

Query: 239 NPMRVLLKIAKSEPPTLAQPSKWSSNFKDFLRKCLEKNVDARWTTSQLLQHPF 291
                      S     A+P   S  F + L   L+K+   R + + L++H F
Sbjct: 352 -----------SGSRLSAKP---SPEFLNLLESLLQKDSTRRLSWASLVKHAF 468
>07836
          Length = 1478

 Score = 43.5 bits (101), Expect = 6e-04,   Method: Composition-based stats.
 Identities = 44/191 (23%), Positives = 83/191 (43%), Gaps = 30/191 (15%)
 Frame = -1

Query: 104  LWILIEFCAGGAVDAVMLELERPLTESQIQVVCKQTLEALNYLH--------DNKIIHRD 155
            L+++ ++   G++   +L   R L  S++  +    +  L +LH           I HRD
Sbjct: 1328 LFLITDYHENGSLHDYLLS--RVLDSSEMLALAHSAICGLAHLHIEIFGTRGKPAIAHRD 1155

Query: 156  LKAGNILFTLDGDIKLADFGVSAKNTRTIQRRD----SFIGTPYWMAPEVV-MCETSKDR 210
            +K+ NIL   +G   +AD G++ +        D       GT  +MAPEV+ M    K+ 
Sbjct: 1154 IKSKNILVKKNGTCCIADLGLAVRYISESNEVDVAPNPRQGTKRYMAPEVLEMLLNVKNF 975

Query: 211  PYDYKADVWSLGITLIEMA----------EIEPPHHELNP-------MRVLLKIAKSEPP 253
                +AD+++ G+ + E+A          E + P +   P       +R+++ + K  P 
Sbjct: 974  DAFKQADMYAFGLVMWEIARCCVIGGVAEEYQVPFYNCLPHDPSFEDVRLVVSVDKVRPD 795

Query: 254  TLAQPSKWSSN 264
                P +W  +
Sbjct: 794  I---PLRWQED 771
>20559
          Length = 430

 Score = 43.5 bits (101), Expect = 6e-04,   Method: Compositional matrix adjust.
 Identities = 25/77 (32%), Positives = 43/77 (55%), Gaps = 2/77 (2%)
 Frame = -2

Query: 34  WEIIGELGDGAFGKVYKAQNKETNVLAAAKVI--DTKSEEELEDYMVEIDILASCDHPNI 91
           +E + ++G+G +G V+KA+N+ET+ + A K +  D   E      + EI +L    H NI
Sbjct: 369 YEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKHRNI 190

Query: 92  VKLLDAFYYENNLWILI 108
           V+L D  + E  L ++ 
Sbjct: 189 VRLHDVLHSERKLTLVF 139
>32691
          Length = 295

 Score = 43.1 bits (100), Expect = 6e-04,   Method: Compositional matrix adjust.
 Identities = 18/34 (52%), Positives = 23/34 (67%)
 Frame = +1

Query: 259 SKWSSNFKDFLRKCLEKNVDARWTTSQLLQHPFV 292
           +KWS+ F DF+ KCL KN + R T   LLQH F+
Sbjct: 79  TKWSTEFIDFVSKCLVKNPENRATAVDLLQHDFI 180
>25019
          Length = 730

 Score = 41.6 bits (96), Expect = 0.002,   Method: Composition-based stats.
 Identities = 23/69 (33%), Positives = 36/69 (52%)
 Frame = +3

Query: 158 AGNILFTLDGDIKLADFGVSAKNTRTIQRRDSFIGTPYWMAPEVVMCETSKDRPYDYKAD 217
           A N+L   DG +KL DFG+  +     +   +F GT  +MAPE ++  T   +  D+   
Sbjct: 258 AENVLLDKDGHVKLTDFGLCKEAITGTRVTHTFCGTIEYMAPE-ILTRTGHGKAVDW--- 425

Query: 218 VWSLGITLI 226
            WSLG + +
Sbjct: 426 -WSLGSSYV 449
>31489
          Length = 329

 Score = 41.6 bits (96), Expect = 0.002,   Method: Composition-based stats.
 Identities = 17/39 (43%), Positives = 24/39 (61%)
 Frame = +3

Query: 124 ERPLTESQIQVVCKQTLEALNYLHDNKIIHRDLKAGNIL 162
           ++PLTE  I+    Q L  L Y+H   ++HRDLK  N+L
Sbjct: 147 DQPLTEEHIRYFLYQILRGLKYIHSANVVHRDLKPSNLL 263
>17300
          Length = 480

 Score = 40.8 bits (94), Expect = 0.003,   Method: Composition-based stats.
 Identities = 34/113 (30%), Positives = 52/113 (46%), Gaps = 5/113 (4%)
 Frame = +1

Query: 142 ALNYLHDNKIIHRDLKAGNILFTLDGDIKLADFGVSAK-NTRTIQRRDSFIGTPY---WM 197
            +  L D   +HRDL A NIL       K+ADFG+S +  + T +   +  G      W 
Sbjct: 10  GMGXLADMGYVHRDLAARNILVNEILVCKVADFGLSREIESDTTEGAYTTKGGKIPVRWT 189

Query: 198 APEVVMCETSKDRPYDYKADVWSLGITLIE-MAEIEPPHHELNPMRVLLKIAK 249
           APE +       R +   +DVWS G+ + E M+  E P+   +   V+  + K
Sbjct: 190 APEAIAY-----RKFTSASDVWSFGVVMWEVMSYGERPYWNWSNQDVIKAVEK 333
>29011
          Length = 374

 Score = 35.4 bits (80), Expect(2) = 0.009,   Method: Compositional matrix adjust.
 Identities = 15/29 (51%), Positives = 20/29 (68%)
 Frame = +2

Query: 265 FKDFLRKCLEKNVDARWTTSQLLQHPFVT 293
           FK FL KCL+  V++R +   LL HPF+T
Sbjct: 92  FKTFLDKCLQVEVESRSSAVDLLTHPFLT 178

 Score = 23.1 bits (48), Expect(2) = 0.009,   Method: Composition-based stats.
 Identities = 10/32 (31%), Positives = 15/32 (46%)
 Frame = +1

Query: 240 PMRVLLKIAKSEPPTLAQPSKWSSNFKDFLRK 271
           P+R L  IA    P +      S + +DF R+
Sbjct: 16  PLRALYLIASHGRPEITSWDSTSPDLQDFFRQ 111
>31789
          Length = 676

 Score = 38.9 bits (89), Expect = 0.012,   Method: Compositional matrix adjust.
 Identities = 29/113 (25%), Positives = 57/113 (50%), Gaps = 8/113 (7%)
 Frame = +2

Query: 39  ELGDGAFGKVYKAQNKETNV-LAAAKVIDTK-SEEELEDYMVEIDILASCDHPNIVKLLD 96
           E+G G+F  VYK  + E  V +A  ++ D K ++ E + +  E ++L    HPNIV+  D
Sbjct: 341 EIGRGSFKTVYKGLDTELGVAVAWCELQDKKWNKTERQRFKEEAEMLKELQHPNIVRFFD 520

Query: 97  AFYYENN------LWILIEFCAGGAVDAVMLELERPLTESQIQVVCKQTLEAL 143
            ++ E+N      + ++ E    G +   +   ++ +    ++  C+Q L+ L
Sbjct: 521 -YWEEHNHRNRKVIILVTELMTSGTLKTYLKRFKK-INLKVLKNWCRQILKGL 673
>17516
          Length = 453

 Score = 38.9 bits (89), Expect = 0.015,   Method: Composition-based stats.
 Identities = 19/40 (47%), Positives = 26/40 (65%)
 Frame = -3

Query: 189 SFIGTPYWMAPEVVMCETSKDRPYDYKADVWSLGITLIEM 228
           +  GTP +MAPEV++    +   YD KADV+SL I L E+
Sbjct: 442 TLAGTPVYMAPEVLL----QKGQYDMKADVYSLAIILWEL 335
>06358
          Length = 1517

 Score = 38.1 bits (87), Expect = 0.022,   Method: Compositional matrix adjust.
 Identities = 61/240 (25%), Positives = 98/240 (40%), Gaps = 37/240 (15%)
 Frame = +3

Query: 37  IGELGDGAFGKVYKAQNKETNVLAAAKVIDTKS---------EEELEDYMVEIDILASCD 87
           +   G G   KV+ A  K T   A+  V + KS         E  +E   V +  L    
Sbjct: 21  VASAGPGLLWKVFAASKKSTKEEASVFVFEKKSVDRYSRRDREAIVEVLRVGVQQLTKLR 200

Query: 88  HPNIVKLLD---------AFYYENNLWILIEFCAG-GAVDAVMLELE-RPLTESQIQVVC 136
           HP I+ +++         AF  E     L        ++  V  EL+   L + +I+   
Sbjct: 201 HPKILAVINPLEESRETLAFATEPVFASLANVLGDLSSIXTVPKELQDYQLYDVEIKHGL 380

Query: 137 KQTLEALNYLH-DNKIIHRDLKAGNILFTLDGDIKLA--DFGVSAKNTRTIQRRDSF--- 190
            Q  EAL +LH D K++HR++    I+ T  G  KLA  +F V + + ++      F   
Sbjct: 381 LQVTEALGFLHNDAKMMHRNVCPEAIMLTKLGSWKLAGYEFCVRSSDPQSTDPSYPFYEW 560

Query: 191 ------IGTPY--WMAPEVVM---CETSKDRPYDYKADVWSLGITLIEMAEIEPPHHELN 239
                 +  P+  +MAPE V+   C T         +D++SLG+ +  +     P  E N
Sbjct: 561 RSDIAPVTQPHLDFMAPEYVLTMQCGTG--------SDMFSLGLLVYSVFAKGKPLFECN 716
>08294
          Length = 1849

 Score = 38.1 bits (87), Expect = 0.023,   Method: Compositional matrix adjust.
 Identities = 37/170 (21%), Positives = 67/170 (39%), Gaps = 24/170 (14%)
 Frame = +2

Query: 86   CDH--PNIVKLLDAFYYENNLWILIEFCAGGAVDAVMLELER-----------PLTESQI 132
            C H  PNIV  +         +++ E+C  G +   +L                L  SQ 
Sbjct: 872  CPHGAPNIVHFMGVCREAEPHFLITEYCDWGDLKQFLLATRNDNGRGRGTRVPALALSQK 1051

Query: 133  QVVCKQTLEALNYLHDNKIIHRDLKAGNILFT-----------LDGDIKLADFGVSAKNT 181
              + +Q    +  L +  ++H DL A N+L T           L GD+  +++     + 
Sbjct: 1052 LGMGQQVAAGMEALSNQGLVHGDLAARNVLLTSRMQLKVARPALSGDVYASEY--YPLHQ 1225

Query: 182  RTIQRRDSFIGTPYWMAPEVVMCETSKDRPYDYKADVWSLGITLIEMAEI 231
            R +  R        W+ PE V+ +++         DVW+ G+ L E+ ++
Sbjct: 1226 RLVPLR--------WLPPEGVLEDSATT-----CGDVWAFGVFLWEVLQL 1336
>18481
          Length = 437

 Score = 37.4 bits (85), Expect = 0.033,   Method: Composition-based stats.
 Identities = 28/101 (27%), Positives = 47/101 (46%), Gaps = 5/101 (4%)
 Frame = -1

Query: 88  HPNIVKLLDAFYY--ENNLWILIEFCAGGAVDAVMLELERPLTESQIQVVCKQTLEALNY 145
           HP +  +   ++Y  E +   L+    G +++ + +  +R  T   I +V  Q L  L +
Sbjct: 320 HPGLPTM---YHYGTEKHFNALVMELLGPSLEELFVICKRRFTLKTILMVSDQLLSRLEF 150

Query: 146 LHDNKIIHRDLKAGNILFTLDGD---IKLADFGVSAKNTRT 183
           +H    IHRDLK  N L  L      + + DFG+S +   T
Sbjct: 149 IHQKCFIHRDLKPDNFLMGLGRHCHRLYIIDFGLSKRYKDT 27
>01106
          Length = 878

 Score = 37.4 bits (85), Expect = 0.038,   Method: Composition-based stats.
 Identities = 33/146 (22%), Positives = 67/146 (45%), Gaps = 13/146 (8%)
 Frame = +3

Query: 34  WEIIGELGDGAFGKVYKAQNKETNVLAAAKVIDTKSEEELEDYMVEIDILASCDHPNI-- 91
           + +I +LG G F  V+   +       A KV+ + ++   E  + E+ +L      ++  
Sbjct: 324 YHVIRKLGWGHFSTVWLCWDLTCKRFVALKVVKS-AQHYTETALDEVKLLKCVRESDVAD 500

Query: 92  ------VKLLDAFYYE----NNLWILIEFCAGGAVDAVMLELERPLTESQIQVVCKQTLE 141
                 V+LLD F        ++ ++ E      +  ++    + +    ++++ +Q LE
Sbjct: 501 PARAKCVQLLDDFKISGVNGTHVAMVFEVLGYNLLKLIIRSNYQGIPIHNVKLIIRQVLE 680

Query: 142 ALNYLHDN-KIIHRDLKAGNILFTLD 166
            L+Y+H   +IIH D+K  NIL  +D
Sbjct: 681 GLSYMHAKCRIIHTDIKPENILICVD 758
>37063
          Length = 455

 Score = 37.4 bits (85), Expect = 0.039,   Method: Composition-based stats.
 Identities = 16/35 (45%), Positives = 22/35 (62%)
 Frame = -2

Query: 191 IGTPYWMAPEVVMCETSKDRPYDYKADVWSLGITL 225
           +G+  +MAPEVV     +   YD + D+WSLGI L
Sbjct: 325 VGSAEYMAPEVVDAWVGESFSYDKRCDMWSLGIIL 221
>00394
          Length = 548

 Score = 37.0 bits (84), Expect = 0.053,   Method: Compositional matrix adjust.
 Identities = 23/65 (35%), Positives = 37/65 (56%), Gaps = 2/65 (3%)
 Frame = -2

Query: 39  ELGDGAFGKVYKAQNKETNV-LAAAKVIDTK-SEEELEDYMVEIDILASCDHPNIVKLLD 96
           E+G G+F  VYK  + E  V +A  ++ D K ++ E + +  E ++L    HPNIV+  D
Sbjct: 277 EIGRGSFKTVYKGLDTELGVAVAWCELQDKKWNKAERQRFKEEAEMLKELQHPNIVRFFD 98

Query: 97  AFYYE 101
             Y+E
Sbjct: 97  --YWE 89
>00486
          Length = 797

 Score = 36.6 bits (83), Expect = 0.065,   Method: Composition-based stats.
 Identities = 27/92 (29%), Positives = 43/92 (46%)
 Frame = -2

Query: 189 SFIGTPYWMAPEVVMCETSKDRPYDYKADVWSLGITLIEMAEIEPPHHELNPMRVLLKIA 248
           +F GT  +MAPE+ +  T   +  D+    WSLG  + +M    PP    N  + + KI 
Sbjct: 781 TFCGTIEYMAPEI-LTRTGHGKAVDW----WSLGALMYDMLTGSPPFTAENRKKTIDKIL 617

Query: 249 KSEPPTLAQPSKWSSNFKDFLRKCLEKNVDAR 280
           K +   L  P   ++  +  ++K L KN   R
Sbjct: 616 KGK---LNLPPYLTNEARGLIKKLLRKNPAER 530
>21800
          Length = 855

 Score = 36.6 bits (83), Expect = 0.066,   Method: Composition-based stats.
 Identities = 17/36 (47%), Positives = 24/36 (66%), Gaps = 1/36 (2%)
 Frame = +2

Query: 132 IQVVCKQTLEALNYLHDN-KIIHRDLKAGNILFTLD 166
           ++++ +Q LE LNYLH    IIH D+K  NIL  +D
Sbjct: 638 VKLIIRQVLEGLNYLHAKCNIIHTDIKPENILICVD 745
>17806
          Length = 433

 Score = 36.6 bits (83), Expect = 0.072,   Method: Compositional matrix adjust.
 Identities = 27/82 (32%), Positives = 43/82 (52%), Gaps = 6/82 (7%)
 Frame = +1

Query: 39  ELGDGAFGKVYKA-QNKETNVLAAAKVI-----DTKSEEELEDYMVEIDILASCDHPNIV 92
           ELG G FGKV ++   + T  ++ +KV+     D  +++E   +  E+      DHPNIV
Sbjct: 70  ELGTGWFGKVIESDAERITTGVSRSKVVVKMLKDDATKDEQLLFFEEVAPFRELDHPNIV 249

Query: 93  KLLDAFYYENNLWILIEFCAGG 114
           +LL      N + +L+E  A G
Sbjct: 250 RLLGQCTEMNPMLMLMECAALG 315
>32359
          Length = 928

 Score = 36.2 bits (82), Expect = 0.094,   Method: Compositional matrix adjust.
 Identities = 33/128 (25%), Positives = 60/128 (46%), Gaps = 15/128 (11%)
 Frame = -1

Query: 40  LGDGAFGKVYKAQNKETNVLAAAKVI--DTKSEEELEDYMVEIDILASCDHPNIVKLLDA 97
           +G+G+FG VY+A+  +T+ L A K +  D + +        E+ I+   +H NIVKL   
Sbjct: 406 IGNGSFGVVYQAKLVDTSELVAIKKVLQDKRFKNR------ELQIMRKLEHQNIVKLKFF 245

Query: 98  FYY------ENNLWILIEFCAGGAVDAVMLELERPLTESQ-------IQVVCKQTLEALN 144
           FY       E  L +++E+     V   +  + R  ++S+       I++   Q   +L 
Sbjct: 244 FYSSGEKKDEVFLNLVLEY-----VPETVYRVARHYSKSKQTIPILYIKLYMYQLFRSLA 80

Query: 145 YLHDNKII 152
           Y+H    +
Sbjct: 79  YIHSQACV 56
>32000
          Length = 644

 Score = 35.4 bits (80), Expect = 0.13,   Method: Composition-based stats.
 Identities = 31/153 (20%), Positives = 64/153 (41%), Gaps = 26/153 (16%)
 Frame = -1

Query: 165 LDGDIKLADFGVSAKNTRTIQRRDSFIGTPYWMAPEVVM-CETSKDRPYDYKADVWSLGI 223
           +   +K+ADFG++      ++     + T ++ APE+++ C     R Y    D+WSLG 
Sbjct: 584 MTAKMKIADFGLARVFGLPVRTYTHEVITLWYRAPEILLGC-----RFYSVPVDIWSLGC 420

Query: 224 TLIEMA---EIEPPHHELNPM-RVLLKIAKSEP---PTLAQPSKWSSNFK---------- 266
             +EM     + P   E++ + R+   +   +    P +++   +   F           
Sbjct: 419 IFVEMMTRRALFPGDSEIDQLYRIFRTLGTPDEKVWPGVSKLPDYKPTFPKWPLKNLETV 240

Query: 267 --------DFLRKCLEKNVDARWTTSQLLQHPF 291
                   D L++ L  N + R +    ++HP+
Sbjct: 239 VSLSKVGLDLLKRMLTYNPNRRISARSAMRHPY 141
>18663
          Length = 600

 Score = 35.4 bits (80), Expect = 0.16,   Method: Composition-based stats.
 Identities = 17/46 (36%), Positives = 25/46 (54%)
 Frame = +2

Query: 189 SFIGTPYWMAPEVVMCETSKDRPYDYKADVWSLGITLIEMAEIEPP 234
           +F GTP ++APE++  E      Y +  D W+LG+ L EM     P
Sbjct: 5   TFCGTPNYIAPEILRGED-----YGFSVDWWALGVLLYEMLAGRSP 127
>20152
          Length = 445

 Score = 35.0 bits (79), Expect = 0.18,   Method: Composition-based stats.
 Identities = 27/95 (28%), Positives = 42/95 (44%), Gaps = 1/95 (1%)
 Frame = +1

Query: 199 PEVVMCETSKDRPYDYKA-DVWSLGITLIEMAEIEPPHHELNPMRVLLKIAKSEPPTLAQ 257
           PE+++ ++     YD  A DVWSLG+ L  +   E P  E N    L  I          
Sbjct: 1   PEILLGDS-----YDAPAVDVWSLGVILYMLVVGEAPFQEANDSETLTMIMDCR---YQI 156

Query: 258 PSKWSSNFKDFLRKCLEKNVDARWTTSQLLQHPFV 292
           P   S   +D + K L++    R +   +L HP++
Sbjct: 157 PPHISHKCQDLIEKMLQREPVDRASLPHILAHPWL 261
>29360
          Length = 363

 Score = 35.0 bits (79), Expect = 0.19,   Method: Compositional matrix adjust.
 Identities = 31/120 (25%), Positives = 52/120 (43%), Gaps = 5/120 (4%)
 Frame = +3

Query: 50  KAQNKETNVLAAAKVIDTKSEEELEDYMVEIDILA-----SCDHPNIVKLLDAFYYENNL 104
           K   K T+ + A K++        +   +E+ IL      S D  N V+  + F ++N+ 
Sbjct: 6   KCWKKGTSEIVAIKILKNHPSYARQG-QIEVSILQRLSQESADDYNFVRAFECFQHKNHT 182

Query: 105 WILIEFCAGGAVDAVMLELERPLTESQIQVVCKQTLEALNYLHDNKIIHRDLKAGNILFT 164
            ++ E       D +     +PL    I+ + +Q L AL  L    +IH DLK  NI+  
Sbjct: 183 CLVFEMLEQNLYDFLKQNKFQPLPLKYIRPITQQVLTALRKLKQLGLIHADLKPENIMLV 362
>27274
          Length = 396

 Score = 33.9 bits (76), Expect = 0.36,   Method: Composition-based stats.
 Identities = 23/84 (27%), Positives = 36/84 (42%), Gaps = 8/84 (9%)
 Frame = -1

Query: 217 DVWSLGITLIEMAEIEPP--------HHELNPMRVLLKIAKSEPPTLAQPSKWSSNFKDF 268
           D+WSLGI L E+     P            N M V  +I +     +      S++  DF
Sbjct: 339 DMWSLGILLHELLSGHVPFEPERGSRQMARNMMAVYAQIIRGSSRDVCDGLALSTHGADF 160

Query: 269 LRKCLEKNVDARWTTSQLLQHPFV 292
           LR+ ++     R T+ Q   HP++
Sbjct: 159 LRRLVQLEDTKRLTSQQAFSHPWI 88
>31120
          Length = 439

 Score = 32.7 bits (73), Expect = 0.97,   Method: Composition-based stats.
 Identities = 28/93 (30%), Positives = 47/93 (50%), Gaps = 4/93 (4%)
 Frame = +1

Query: 211 PYDYK-ADVWSLGITLIEMAEIEPPHHELNPMRVLLKIAKSEPPTLAQPSK--WSSNFKD 267
           PYD K AD WSLG+ L  M   + P  + N +  LL+  +S+  +  +  +   S N + 
Sbjct: 19  PYDPKMADAWSLGVILFIMLNGKMPFDDSN-LNKLLEDQRSKKYSFRRKLQDLVSPNARS 195

Query: 268 FLRKCLEKNVDARWTTSQLLQHPFV-TVDSNKP 299
            +   LE N   RW  +++L   ++ T+D  +P
Sbjct: 196 TVSVLLEPNSAMRWDLNEVLNCQWLQTIDEPRP 294
>29590
          Length = 320

 Score = 32.3 bits (72), Expect = 1.3,   Method: Composition-based stats.
 Identities = 17/43 (39%), Positives = 24/43 (55%)
 Frame = +3

Query: 181 TRTIQRRDSFIGTPYWMAPEVVMCETSKDRPYDYKADVWSLGI 223
           T T +     IGTP ++APEV+  E     P   + D+WSLG+
Sbjct: 27  TNTGEDIRDIIGTPDYVAPEVLDYE-----PLSIQTDMWSLGV 140
>20513
          Length = 405

 Score = 31.2 bits (69), Expect = 2.8,   Method: Compositional matrix adjust.
 Identities = 14/35 (40%), Positives = 22/35 (62%)
 Frame = -1

Query: 262 SSNFKDFLRKCLEKNVDARWTTSQLLQHPFVTVDS 296
           +  F DFL   LE + + R T +Q LQHP++ +D+
Sbjct: 297 AKAFADFLAPMLEFDPEQRATAAQSLQHPWLKLDA 193
>32957
          Length = 645

 Score = 30.8 bits (68), Expect = 3.4,   Method: Composition-based stats.
 Identities = 18/51 (35%), Positives = 25/51 (49%)
 Frame = +3

Query: 186 RRDSFIGTPYWMAPEVVMCETSKDRPYDYKADVWSLGITLIEMAEIEPPHH 236
           R  +F GT  +MAPEV      + + Y  + D W LGI L E+   +   H
Sbjct: 33  RTRTFCGTREYMAPEV-----HERKEYGKEVDWWGLGILLHELLAAQIKKH 170
>16350
          Length = 1108

 Score = 30.0 bits (66), Expect = 5.8,   Method: Composition-based stats.
 Identities = 14/32 (43%), Positives = 21/32 (65%)
 Frame = +3

Query: 265 FKDFLRKCLEKNVDARWTTSQLLQHPFVTVDS 296
           F DFL   LE + + R T +Q LQHP++ +D+
Sbjct: 756 FADFLAPMLEFDPEQRATAAQSLQHPWLKLDA 851
>24241
          Length = 413

 Score = 29.6 bits (65), Expect = 7.7,   Method: Composition-based stats.
 Identities = 21/77 (27%), Positives = 38/77 (49%), Gaps = 3/77 (3%)
 Frame = -2

Query: 37  IGELGDGAFGKVYKAQNKETNVLAAAKVIDTKSEEE--LEDYMVEIDILASCDHPN-IVK 93
           + ++G+G +G VYK +++ T    A K I  +  E+      + EI +L    H   +V 
Sbjct: 328 LSKIGEGTYGVVYKCRHRATGRKLAMKKIRLRGSEDGVPSSAIREIAMLRELRHTQXLVC 149

Query: 94  LLDAFYYENNLWILIEF 110
           L D    +  L+++ EF
Sbjct: 148 LEDVIMEDERLFLVFEF 98
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|21704066|ref|NP_663516.1| RAS-related protein-1a [Mus
musculus]
         (184 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

07580                                                                 264   2e-73
00858                                                                 148   1e-36
06994                                                                 116   2e-31
19046                                                                  91   3e-19
24619                                                                  88   2e-18
26536                                                                  86   7e-18
08428                                                                  79   8e-16
34468                                                                  76   7e-15
07465                                                                  75   1e-14
36482                                                                  74   4e-14
11257                                                                  72   2e-13
33374                                                                  69   9e-13
33380                                                                  67   4e-12
01972                                                                  64   3e-11
18509                                                                  60   4e-11
34597                                                                  60   6e-10
01398                                                                  58   2e-09
05468                                                                  58   2e-09
34359                                                                  57   5e-09
19006                                                                  57   6e-09
13745                                                                  56   9e-09
12339                                                                  55   1e-08
11728                                                                  55   1e-08
01095                                                                  52   1e-07
29380                                                                  51   3e-07
32723                                                                  49   1e-06
31928                                                                  48   3e-06
19656                                                                  46   8e-06
14119                                                                  37   0.004
25618                                                                  37   0.004
10708                                                                  36   0.008
>07580
          Length = 921

 Score =  264 bits (675), Expect(2) = 2e-73,   Method: Compositional matrix adjust.
 Identities = 127/146 (86%), Positives = 139/146 (95%)
 Frame = +3

Query: 25  QGIFVEKYDPTIEDSYRKQVEVDCQQCMLEILDTAGTEQFTAMRDLYMKNGQGFALVYSI 84
           +GIFVEKYDPTIEDSYRKQVEVD QQCMLEILDTAGTEQFTAMRDLYMKNGQGF L YSI
Sbjct: 126 KGIFVEKYDPTIEDSYRKQVEVDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFLLAYSI 305

Query: 85  TAQSTFNDLQDLREQILRVKDTEDVPMILVGNKCDLEDERVVGKEQGQNLARQWCNCAFL 144
           TAQSTFNDLQ+LREQILRVKDT+DVPM+LVGNKCDLEDERVVGK+QGQ LAR + +CAFL
Sbjct: 306 TAQSTFNDLQELREQILRVKDTDDVPMLLVGNKCDLEDERVVGKDQGQGLARSF-SCAFL 482

Query: 145 ESSAKSKINVNEIFYDLVRQINRKTP 170
           E+SAK++INVNEIF DLVRQIN+K+P
Sbjct: 483 ETSAKARINVNEIFMDLVRQINKKSP 560

 Score = 28.1 bits (61), Expect(2) = 2e-73,   Method: Compositional matrix adjust.
 Identities = 15/31 (48%), Positives = 15/31 (48%)
 Frame = +2

Query: 1  MREYXXXXXXXXXXXXXALTVQFVQGIFVEK 31
          MREY             ALTVQFVQG F  K
Sbjct: 53 MREYKLVVLGSGGVGKSALTVQFVQGDFCGK 145
>00858
          Length = 1658

 Score =  148 bits (373), Expect = 1e-36,   Method: Compositional matrix adjust.
 Identities = 77/165 (46%), Positives = 109/165 (66%)
 Frame = -2

Query: 1    MREYXXXXXXXXXXXXXALTVQFVQGIFVEKYDPTIEDSYRKQVEVDCQQCMLEILDTAG 60
            M EY             ALT+Q  Q  FVE+YDPT EDS RKQV +D + C+L+ILDTAG
Sbjct: 1597 MTEYKLVVVGAGGVGKSALTIQLXQNHFVEEYDPTXEDSXRKQVVIDGETCLLDILDTAG 1418

Query: 61   TEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTEDVPMILVGNKCDL 120
             E+ +AMRD  M+ G+GF  V+++    +F D+   REQI RVKD ++VPM+LVGNK DL
Sbjct: 1417 QEEXSAMRDQCMRTGEGFLCVFAVXNLKSFEDINQYREQIKRVKDADEVPMVLVGNKVDL 1238

Query: 121  EDERVVGKEQGQNLARQWCNCAFLESSAKSKINVNEIFYDLVRQI 165
               R V + QG+++A  + +  ++E+SAK++  V++ FY LVR+I
Sbjct: 1237 PI-RNVEQRQGKHMAELY-HIPYVETSAKTRQGVDDAFYTLVREI 1109
>06994
          Length = 429

 Score =  116 bits (291), Expect(2) = 2e-31,   Method: Compositional matrix adjust.
 Identities = 62/103 (60%), Positives = 65/103 (63%), Gaps = 32/103 (31%)
 Frame = +1

Query: 25  QGIFVEKYDPTIEDSYRKQVEVDCQQCMLEILDTAGT----------------------- 61
           +G   +KYDPTIEDSYRKQVEVD QQCMLEILDTAGT                       
Sbjct: 121 KGFLWKKYDPTIEDSYRKQVEVDGQQCMLEILDTAGTVHASHSNACVHGSLHAFVGTVTP 300

Query: 62  ---------EQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQD 95
                    EQFTAMRDLYMKNGQGF L YSITAQSTFNDLQ+
Sbjct: 301 LGRDALLNTEQFTAMRDLYMKNGQGFLLAYSITAQSTFNDLQE 429

 Score = 35.8 bits (81), Expect(2) = 2e-31,   Method: Compositional matrix adjust.
 Identities = 18/31 (58%), Positives = 18/31 (58%)
 Frame = +3

Query: 1  MREYXXXXXXXXXXXXXALTVQFVQGIFVEK 31
          MREY             ALTVQFVQGIFVEK
Sbjct: 48 MREYKLVVLGSGGVGKSALTVQFVQGIFVEK 140
>19046
          Length = 445

 Score = 90.5 bits (223), Expect = 3e-19,   Method: Compositional matrix adjust.
 Identities = 47/110 (42%), Positives = 71/110 (64%), Gaps = 1/110 (0%)
 Frame = -2

Query: 62  EQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTEDVPMILVGNKCDLE 121
           E+F+AMR+ YM+ G GF LV+S+T   +F ++ +   QILRVKD +  PMIL  NK DL 
Sbjct: 441 EEFSAMREQYMRKGDGFLLVFSVTDFRSFENMANFHTQILRVKDRDSYPMILCANKVDLV 262

Query: 122 DERVVGKEQGQNLARQWCNCAFLESSAK-SKINVNEIFYDLVRQINRKTP 170
            +R V +EQ ++LA +     ++E+SAK   +NV+  F+ +VR I  + P
Sbjct: 261 HQRKVSEEQVRDLATR-LRIPYIETSAKDPPLNVDLAFHQVVRVIRAQPP 115
>24619
          Length = 509

 Score = 88.2 bits (217), Expect = 2e-18,   Method: Compositional matrix adjust.
 Identities = 46/110 (41%), Positives = 70/110 (63%), Gaps = 1/110 (0%)
 Frame = -2

Query: 62  EQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTEDVPMILVGNKCDLE 121
           E+F+AMR+ YM+ G GF LV+S+    +F ++ +   QILRVKD +  PMIL  NK DL 
Sbjct: 505 EEFSAMREQYMRKGDGFLLVFSVIDYQSFENMVNFHTQILRVKDRDTYPMILCANKVDLV 326

Query: 122 DERVVGKEQGQNLARQWCNCAFLESSAK-SKINVNEIFYDLVRQINRKTP 170
            +R V +EQ ++LA +     ++E+SAK   +NV+  F+ +VR I  + P
Sbjct: 325 HQRKVSEEQVRDLATR-LRIPYIETSAKDPPLNVDLAFHQVVRVIRAQPP 179
>26536
          Length = 829

 Score = 86.3 bits (212), Expect = 7e-18,   Method: Compositional matrix adjust.
 Identities = 40/113 (35%), Positives = 72/113 (63%)
 Frame = +2

Query: 55  ILDTAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTEDVPMILV 114
            LDTAG E++++MR+ Y ++G GF +VYS+T  ++F + + +   + R +D   +  +L 
Sbjct: 140 FLDTAGQEEYSSMREHYTRSGDGFIVVYSVTDVTSFQEAEAVFRWLTRFQDETSIHAVLC 319

Query: 115 GNKCDLEDERVVGKEQGQNLARQWCNCAFLESSAKSKINVNEIFYDLVRQINR 167
           GNK DL  +R V  E+G+ +A +     + E+SAK+  NV+++++ L+R I R
Sbjct: 320 GNKTDLTSDRKVTPEEGRKMADR-LGMLYFETSAKTGDNVSQVYHGLLRSIPR 475

 Score = 44.7 bits (104), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 18/32 (56%), Positives = 25/32 (78%)
 Frame = +2

Query: 18  ALTVQFVQGIFVEKYDPTIEDSYRKQVEVDCQ 49
           +LT++F Q  F++ YDPTIEDSYRK ++V  Q
Sbjct: 530 SLTIRFTQDTFLDVYDPTIEDSYRKMIQVSGQ 625
>08428
          Length = 1109

 Score = 79.3 bits (194), Expect = 8e-16,   Method: Compositional matrix adjust.
 Identities = 47/149 (31%), Positives = 80/149 (53%), Gaps = 1/149 (0%)
 Frame = -3

Query: 18   ALTVQFVQGIFVEKYDPTIEDSY-RKQVEVDCQQCMLEILDTAGTEQFTAMRDLYMKNGQ 76
            ++ ++FV G +    + TI  S+  K + VD      +I DTAG E+F A+  +Y +   
Sbjct: 1026 SIVLRFVTGSYRPSQESTIGASFMSKSLVVDGAGYRFQIWDTAGQEKFRALAPMYYRGAA 847

Query: 77   GFALVYSITAQSTFNDLQDLREQILRVKDTEDVPMILVGNKCDLEDERVVGKEQGQNLAR 136
               +VY +T   TF  ++   ++ LR     ++ + + GNKCDLE+ R V ++  Q  A 
Sbjct: 846  AAVIVYDVTRPRTFKSVKSWIQE-LRSFGPPNIVLAIAGNKCDLEELREVVEKDAQEYAS 670

Query: 137  QWCNCAFLESSAKSKINVNEIFYDLVRQI 165
               +  F E+SA + +NV E+F +L RQ+
Sbjct: 669  S-ISAIFGETSAMTAVNVEEMFTELARQL 586
>34468
          Length = 1502

 Score = 76.3 bits (186), Expect = 7e-15,   Method: Compositional matrix adjust.
 Identities = 53/158 (33%), Positives = 80/158 (50%), Gaps = 5/158 (3%)
 Frame = +1

Query: 19  LTVQFVQGIFVEKYDPTIEDSYR-KQVEVDCQQCMLEILDTAGTEQF-TAMRDLYMKNGQ 76
           LT +F  G F +K + TI   +R K ++VD +   L++ DTAG E+F  +M   Y +N  
Sbjct: 541 LTYRFCLGKFPDKTEATIGVDFREKSIQVDSEHLKLQLWDTAGQERFRKSMVQHYYRNVH 720

Query: 77  GFALVYSITAQSTFNDLQDLREQILRVKDTEDVPMILVGNKCDLEDERVVGKEQGQNLAR 136
               VY +T  S+F ++    E+  R   T+ +P ILVGNKCD+ +   V     Q  A 
Sbjct: 721 AVVFVYDMTKMSSFENMPAWIEECDRHNLTKYIPRILVGNKCDVVERIAVNTNLAQKFA- 897

Query: 137 QWCNCAFLESSAK--SKIN-VNEIFYDLVRQINRKTPV 171
              N    E+SAK   K N V+ IF  +  ++    P+
Sbjct: 898 DAHNMPLFETSAKDDEKANHVDAIFMTVAHKLKXSKPM 1011
>07465
          Length = 1103

 Score = 75.1 bits (183), Expect = 1e-14,   Method: Compositional matrix adjust.
 Identities = 44/142 (30%), Positives = 78/142 (54%), Gaps = 1/142 (0%)
 Frame = +3

Query: 18  ALTVQFVQGIFVEKYDPTIE-DSYRKQVEVDCQQCMLEILDTAGTEQFTAMRDLYMKNGQ 76
           ++  ++ +GIF + Y  TI  D   +Q+EV  +   L + DTAG E+F A+   Y +  Q
Sbjct: 243 SMIQRYCKGIFTKDYKKTIGVDFLERQIEVGGEDVRLMLWDTAGQEEFDAITKAYYRGAQ 422

Query: 77  GFALVYSITAQSTFNDLQDLREQILRVKDTEDVPMILVGNKCDLEDERVVGKEQGQNLAR 136
              L +S   + +F  L+  + ++    +  ++ M++V NK DL D+ VV  E+ +NLA+
Sbjct: 423 ACVLAFSTVDRDSFEALETWKRKV--EDEVGEIGMVIVQNKIDLIDDAVVRPEEAENLAK 596

Query: 137 QWCNCAFLESSAKSKINVNEIF 158
           +     F  +S K  +NV+E+F
Sbjct: 597 K-LRLRFYRTSVKENMNVDEVF 659
>36482
          Length = 686

 Score = 73.9 bits (180), Expect = 4e-14,   Method: Compositional matrix adjust.
 Identities = 45/153 (29%), Positives = 79/153 (51%), Gaps = 3/153 (1%)
 Frame = +2

Query: 19  LTVQFVQGIFVEKYDPTIEDSYRKQVEVDCQQCMLEILDTAGTEQFTAMRDLYMKNGQGF 78
           LTV+F+   F+ +Y PT+E  Y+    ++     LEILDTAG   +   ++ Y      F
Sbjct: 2   LTVRFLTRRFIGEYCPTLESVYKYHTVIEDDDVRLEILDTAGQGTY-PWKEGYALWADCF 178

Query: 79  ALVYSITAQSTFNDLQDLREQILRVKDTEDVPMILVGNKCDLEDERVVGKEQGQNLARQW 138
             VYSI  + ++ +L  ++ Q+  V+ +  +  +L  NK DL  +R V +++G++LA + 
Sbjct: 179 VFVYSINDRQSYEELVQVKRQVESVRKSTSLTAVLAANKTDLLHDRQVTQKEGEDLAEE- 355

Query: 139 CNCAFLESSAKSKIN---VNEIFYDLVRQINRK 168
             C   E SA        +  +F+DL R+  + 
Sbjct: 356 IGCRLYEVSASEGSQMEAITSMFHDLYREFRKH 454
>11257
          Length = 1102

 Score = 71.6 bits (174), Expect = 2e-13,   Method: Compositional matrix adjust.
 Identities = 39/128 (30%), Positives = 66/128 (51%), Gaps = 3/128 (2%)
 Frame = -2

Query: 41   RKQVEVDCQQCMLEILDTAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQI 100
             K V VD +   ++I DTAG E++ ++R  + +      L +S+    +   L D  ++ 
Sbjct: 1056 HKDVVVDGETFTMQIWDTAGQERYKSLRTPFYRGTDCCLLTFSVDNLKSLQSLSDWYDEF 877

Query: 101  LRVKDTED---VPMILVGNKCDLEDERVVGKEQGQNLARQWCNCAFLESSAKSKINVNEI 157
            +   D +D    P +++GNK D+E ER V  E   N  R   N  + E+SAK  +NV + 
Sbjct: 876  VNYADIQDSASFPFVIIGNKADIE-EREVSSEDAYNWCRTHGNLPYFETSAKDSLNVQQA 700

Query: 158  FYDLVRQI 165
            F  +VR++
Sbjct: 699  FLAVVRRL 676
>33374
          Length = 489

 Score = 69.3 bits (168), Expect = 9e-13,   Method: Compositional matrix adjust.
 Identities = 38/112 (33%), Positives = 66/112 (58%)
 Frame = +1

Query: 46  VDCQQCMLEILDTAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKD 105
           +D      EI DTAG E++ ++  +Y +  Q   +VY IT Q TF   +   +++ R + 
Sbjct: 160 LDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNQDTFGRAKTWVKELQR-QA 336

Query: 106 TEDVPMILVGNKCDLEDERVVGKEQGQNLARQWCNCAFLESSAKSKINVNEI 157
           + ++ + L GNK DL ++R+V  E+ Q  A +  +  F+E+SAK+ +NVN+I
Sbjct: 337 SPNIVIALAGNKADLANKRMVEFEEAQAYAEE-NSLLFMETSAKTAMNVNDI 489
>33380
          Length = 282

 Score = 67.0 bits (162), Expect = 4e-12,   Method: Compositional matrix adjust.
 Identities = 32/73 (43%), Positives = 47/73 (64%)
 Frame = +3

Query: 53  LEILDTAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTEDVPMI 112
           L+I DTAG E++  +   Y +   GF L+Y +T + +FN +QD   QI +    ++  ++
Sbjct: 66  LQIWDTAGQERYRTITTAYYRGAMGFILMYDVTNEESFNAVQDWCTQI-KTYSWDNAQVV 242

Query: 113 LVGNKCDLEDERV 125
           LVGNKCDLEDERV
Sbjct: 243 LVGNKCDLEDERV 281
>01972
          Length = 2359

 Score = 64.3 bits (155), Expect = 3e-11,   Method: Compositional matrix adjust.
 Identities = 35/113 (30%), Positives = 64/113 (56%)
 Frame = +3

Query: 53  LEILDTAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTEDVPMI 112
             + DTAG E+F  +RD Y   GQ   +++ +T++ T+ ++ +    ++RV   E++P++
Sbjct: 453 FNVWDTAGQEKFGGLRDGYYIQGQCAVIMFDVTSRVTYKNVPNWHRDLVRV--CENIPIV 626

Query: 113 LVGNKCDLEDERVVGKEQGQNLARQWCNCAFLESSAKSKINVNEIFYDLVRQI 165
           L GNK D++D +V  K +     R+  N  + + SAKS  N  + F  L R++
Sbjct: 627 LCGNKVDIKDRKV--KAKAIVFHRK-KNLQYYDISAKSNYNFEKPFLWLARKL 776
>18509
          Length = 625

 Score = 59.7 bits (143), Expect(2) = 4e-11,   Method: Compositional matrix adjust.
 Identities = 30/66 (45%), Positives = 48/66 (72%)
 Frame = -3

Query: 102 RVKDTEDVPMILVGNKCDLEDERVVGKEQGQNLARQWCNCAFLESSAKSKINVNEIFYDL 161
           RVKD ++VPM+LVGNK DL   R V + QG+++A +  +  ++E+SAK++  V++ FY L
Sbjct: 548 RVKDADEVPMVLVGNKVDLPI-RNVEQRQGKHMA-ELYHIPYVETSAKTRQGVDDAFYTL 375

Query: 162 VRQINR 167
           VR+I +
Sbjct: 374 VREIRK 357

 Score = 24.3 bits (51), Expect(2) = 4e-11,   Method: Compositional matrix adjust.
 Identities = 9/25 (36%), Positives = 15/25 (60%)
 Frame = -1

Query: 76  QGFALVYSITAQSTFNDLQDLREQI 100
           +GF  V+++    +F D+   REQI
Sbjct: 625 EGFLCVFAVNNLKSFEDINQYREQI 551
>34597
          Length = 773

 Score = 59.7 bits (143), Expect = 6e-10,   Method: Compositional matrix adjust.
 Identities = 30/64 (46%), Positives = 44/64 (68%)
 Frame = -2

Query: 106 TEDVPMILVGNKCDLEDERVVGKEQGQNLARQWCNCAFLESSAKSKINVNEIFYDLVRQI 165
            EDV  +++GNKCD+ D+RVV KE+G+ +AR+  +  F+E+SAKS IN+   F +L   I
Sbjct: 661 NEDVEKMILGNKCDMTDKRVVSKERGEAIAREH-SIRFMETSAKSNINIERAFCELAEAI 485

Query: 166 NRKT 169
             KT
Sbjct: 484 LDKT 473
>01398
          Length = 1421

 Score = 58.2 bits (139), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 31/102 (30%), Positives = 54/102 (52%)
 Frame = -2

Query: 62   EQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTEDVPMILVGNKCDLE 121
            E+F ++   Y +N  G  +VY IT +STF +L+   E+     +      +++G+K D E
Sbjct: 1417 ERFRSITRSYYRNSVGVIIVYDITKRSTFENLKQWYEEARNHIEPHKAIFLVLGHKSDRE 1238

Query: 122  DERVVGKEQGQNLARQWCNCAFLESSAKSKINVNEIFYDLVR 163
            D R V   +G+  A +     F E+SAKS  N+ ++F  + +
Sbjct: 1237 DARQVTAREGRRFA-EMHGLKFFETSAKSGHNIEDVFAQIAK 1115
>05468
          Length = 1558

 Score = 57.8 bits (138), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 45/153 (29%), Positives = 73/153 (47%), Gaps = 6/153 (3%)
 Frame = -3

Query: 22   QFVQGIFVEKYDPTIE-DSYRKQVEVDCQQCM-LEILDTAGTEQFTAMRDLYMKNGQGFA 79
            ++V   F + Y  TI  D   K +  D    + L++ D AG E+F  M  +Y K   G  
Sbjct: 1484 RYVHQFFSQHYRATIGVDFALKVLNWDADTLIRLQLWDIAGQERFGNMTRVYYKEAVGAF 1305

Query: 80   LVYSITAQSTFNDLQDLREQI---LRVKDTEDVPMILVGNKCDLEDERVVGK-EQGQNLA 135
            +V+ +T  STF+ +   +  +   +++ D   VP +L+ NKCD   E +V    Q     
Sbjct: 1304 VVFDVTRASTFDAVTKWKNDLDSKVQLADGSPVPCVLLANKCDQAKEGLVNNTSQMDEFC 1125

Query: 136  RQWCNCAFLESSAKSKINVNEIFYDLVRQINRK 168
             +     + E+SAK  IN++E    LV +I  K
Sbjct: 1124 SEKGFIGWYETSAKENINIDEAARFLVTRILEK 1026
>34359
          Length = 1042

 Score = 57.0 bits (136), Expect = 5e-09,   Method: Compositional matrix adjust.
 Identities = 24/77 (31%), Positives = 46/77 (59%)
 Frame = +3

Query: 53  LEILDTAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTEDVPMI 112
             + DTAG E+F  +RD Y   G    +++ +T++ T+ ++ +    ++RV   E++P++
Sbjct: 201 FNVWDTAGQEKFGGLRDGYYIQGTCAIIMFDVTSRVTYKNVPNWHRDLVRV--CENIPIV 374

Query: 113 LVGNKCDLEDERVVGKE 129
           L GNK D++D +V  K 
Sbjct: 375 LCGNKVDIKDRKVKAKA 425
>19006
          Length = 568

 Score = 56.6 bits (135), Expect = 6e-09,   Method: Compositional matrix adjust.
 Identities = 34/111 (30%), Positives = 58/111 (52%)
 Frame = -2

Query: 19  LTVQFVQGIFVEKYDPTIEDSYRKQVEVDCQQCMLEILDTAGTEQFTAMRDLYMKNGQGF 78
           L + F +  F E Y PT+ ++Y   +EVD +Q  L + DTAG E +  +R L   +    
Sbjct: 390 LLIVFSKDQFPEVYVPTVFENYVADIEVDSKQVELALWDTAGQEDYDRLRPLSYPDTDVI 211

Query: 79  ALVYSITAQSTFNDLQDLREQILRVKDTEDVPMILVGNKCDLEDERVVGKE 129
            + +SI +  +  ++ +     +R     +VP+ILVGNK DL ++    +E
Sbjct: 210 LMCFSIDSPDSLENIPEKWTPEVR-HFCPNVPIILVGNKKDLRNDENTKRE 61
>13745
          Length = 1045

 Score = 55.8 bits (133), Expect = 9e-09,   Method: Compositional matrix adjust.
 Identities = 32/109 (29%), Positives = 57/109 (52%), Gaps = 7/109 (6%)
 Frame = +2

Query: 62  EQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQIL---RVKDTEDVPMILVGNKC 118
           E+F ++   + +      LVY +TA ++F +L   R++ L     +D E  P +++GNK 
Sbjct: 5   ERFQSLGVAFYRGADCCVLVYDVTAPNSFKNLDSWRDEFLIQASPRDPEHFPFVVLGNKV 184

Query: 119 DLEDERVVGKEQGQNLARQWC----NCAFLESSAKSKINVNEIFYDLVR 163
           DL++ +V  +      A+QWC    +  + E+SAK  INV   F  + +
Sbjct: 185 DLDNRQVSTRR-----AQQWCQSKNDIPYYETSAKEGINVEMAFQTIAK 316
>12339
          Length = 578

 Score = 55.5 bits (132), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 34/109 (31%), Positives = 55/109 (50%), Gaps = 7/109 (6%)
 Frame = -2

Query: 62  EQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILR---VKDTEDVPMILVGNKC 118
           E+F ++   + +      LVY +T   TF+ L   + + L     +D E  P +++GNK 
Sbjct: 574 ERFQSLGVAFYRGADCCILVYDVTEXKTFDSLDSWQREFLNQASPRDPEHFPFVVIGNKI 395

Query: 119 DLEDERVVGKEQGQNLARQWCNC----AFLESSAKSKINVNEIFYDLVR 163
           DL D RVV  ++GQ     WC+      + E+SAK  INV + F  + +
Sbjct: 394 DL-DNRVVTAKRGQG----WCSTKGGIPYFETSAKEAINVEQAFQTVAK 263
>11728
          Length = 635

 Score = 55.5 bits (132), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 34/118 (28%), Positives = 59/118 (50%), Gaps = 1/118 (0%)
 Frame = -1

Query: 19  LTVQFVQGIFVEKYDPTIEDSYRKQVEVDCQQCMLEILDTAGTEQFTAMRDLYMKNGQGF 78
           L + +    F  +Y PT+ D+Y   V VD +   L + DTAG E +  +R L       F
Sbjct: 443 LLISYTTNAFPGEYIPTVFDNYSANVMVDSKPINLGLWDTAGQEDYDRLRPLSYPQTDVF 264

Query: 79  ALVYSITAQSTFNDLQDLREQILRVKDTEDVPMILVGNKCDL-EDERVVGKEQGQNLA 135
            + +S+ + ++F +++  +          + P+ILVG K DL ED+  + K + + LA
Sbjct: 263 LICFSLISPASFENVK-AKWYPEVSHHCPNTPIILVGTKLDLREDKETIEKLKEKKLA 93
>01095
          Length = 1745

 Score = 52.4 bits (124), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 29/88 (32%), Positives = 55/88 (62%)
 Frame = -1

Query: 80   LVYSITAQSTFNDLQDLREQILRVKDTEDVPMILVGNKCDLEDERVVGKEQGQNLARQWC 139
            +VY IT Q TF   +   +++ R + + ++ + L GNK DL ++R+V  E+ Q  A +  
Sbjct: 1745 VVYDITNQDTFGRAKTWVKELQR-QASPNIVIALAGNKADLANKRMVEFEEAQAYAEE-N 1572

Query: 140  NCAFLESSAKSKINVNEIFYDLVRQINR 167
            +  F+E+SAK+ +NVN+IF  + +++ +
Sbjct: 1571 SLLFMETSAKTAMNVNDIFLAIAKKLPK 1488
>29380
          Length = 853

 Score = 50.8 bits (120), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 36/88 (40%), Positives = 50/88 (56%), Gaps = 2/88 (2%)
 Frame = -2

Query: 80  LVYSITAQSTFN-DLQDLREQILRVKDTEDVPMILVGNKCDLEDE-RVVGKEQGQNLARQ 137
           +VY +    TF+  L  ++E  LR ++TE V +IL GNK DL  + R V  E  Q+ AR+
Sbjct: 837 IVYDVNIADTFSRALAWVKE--LRQQNTESVLIILAGNKVDLATQHRAVSFEDAQSFARE 664

Query: 138 WCNCAFLESSAKSKINVNEIFYDLVRQI 165
                F E SAK+ + VNEIF  L  Q+
Sbjct: 663 -NGLLFAEVSAKTGMAVNEIFMTLANQL 583
>32723
          Length = 384

 Score = 48.9 bits (115), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 31/105 (29%), Positives = 52/105 (49%)
 Frame = +2

Query: 62  EQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTEDVPMILVGNKCDLE 121
           E+F ++   Y ++     LVY + +Q ++  L     +I     T+ V   LVGNK D  
Sbjct: 5   ERFRSITQSYYRSANALILVYDVCSQQSYESLPQWIHEIELYAGTK-VLAFLVGNKIDQT 181

Query: 122 DERVVGKEQGQNLARQWCNCAFLESSAKSKINVNEIFYDLVRQIN 166
           D+R +    G+  A ++    FLE+SAK   NV ++F  +  Q+ 
Sbjct: 182 DKREIPTHIGKEFAERY-EMRFLETSAKEADNVEKLFSTIAYQLT 313
>31928
          Length = 429

 Score = 47.8 bits (112), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 31/87 (35%), Positives = 44/87 (50%), Gaps = 4/87 (4%)
 Frame = +2

Query: 35  TIEDSYRKQVEVD-CQQCMLEILDTAGTEQFTAMRDL---YMKNGQGFALVYSITAQSTF 90
           TIED Y   +E D   +  + I DT      T   DL   Y+    GF LVY  T+  +F
Sbjct: 53  TIEDIYTAVIETDRGVKEKVRIFDTGAAALETTEGDLPKHYLNFPDGFVLVYDTTSWESF 232

Query: 91  NDLQDLREQILRVKDTEDVPMILVGNK 117
             L  L++ I + +D  +V MI++GNK
Sbjct: 233 RRLDKLKKDIDKHRDKREVHMIVIGNK 313
>19656
          Length = 428

 Score = 46.2 bits (108), Expect = 8e-06,   Method: Compositional matrix adjust.
 Identities = 22/76 (28%), Positives = 39/76 (51%)
 Frame = +3

Query: 19  LTVQFVQGIFVEKYDPTIEDSYRKQVEVDCQQCMLEILDTAGTEQFTAMRDLYMKNGQGF 78
           L + +    F  +Y PT+ D+Y   V VD +   L + DTAG E +  +R L       F
Sbjct: 159 LLISYTTNAFPGEYIPTVFDNYSANVMVDGRPVNLGLWDTAGQEDYDRLRPLSYPQTDVF 338

Query: 79  ALVYSITAQSTFNDLQ 94
            L +S+ + ++F +++
Sbjct: 339 LLCFSVASPASFENIR 386
>14119
          Length = 602

 Score = 37.4 bits (85), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 22/70 (31%), Positives = 36/70 (51%), Gaps = 1/70 (1%)
 Frame = +1

Query: 101 LRVKDTEDVPMILVGNKCDLEDE-RVVGKEQGQNLARQWCNCAFLESSAKSKINVNEIFY 159
           LR ++   V ++L GNK DL  E R V  +  +  A       F E SAK+ + V+E+F 
Sbjct: 34  LRQQNAGSVLIVLAGNKADLASEHRAVSADDARTFAED-NGLIFAEVSAKTGMAVSEVFM 210

Query: 160 DLVRQINRKT 169
            +  ++ R+ 
Sbjct: 211 TIAHKLVRRA 240
>25618
          Length = 475

 Score = 37.4 bits (85), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 22/70 (31%), Positives = 36/70 (51%), Gaps = 1/70 (1%)
 Frame = +3

Query: 101 LRVKDTEDVPMILVGNKCDLEDE-RVVGKEQGQNLARQWCNCAFLESSAKSKINVNEIFY 159
           LR ++   V ++L GNK DL  E R V  +  +  A       F E SAK+ + V+E+F 
Sbjct: 54  LRQQNAGSVLIVLAGNKADLASEHRAVSADDARTFAED-NGLIFAEVSAKTGMAVSEVFM 230

Query: 160 DLVRQINRKT 169
            +  ++ R+ 
Sbjct: 231 TIAHKLVRRA 260
>10708
          Length = 2775

 Score = 36.2 bits (82), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 22/68 (32%), Positives = 36/68 (52%), Gaps = 12/68 (17%)
 Frame = -3

Query: 108  DVPMILVGNKCDLEDERVVGKE------------QGQNLARQWCNCAFLESSAKSKINVN 155
            +VP+ILVGNK DL ++    +E            +G+ ++ +    ++LE SAK+K  V 
Sbjct: 2554 NVPIILVGNKKDLRNDENTKRELMKMKQEPVRLDEGRAMSEKINAYSYLECSAKTKEGVR 2375

Query: 156  EIFYDLVR 163
            E+F    R
Sbjct: 2374 EVFETATR 2351
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|22094119|ref|NP_035716.1| myosin XVIIIA [Mus
musculus]
         (2035 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

31878                                                                 260   3e-73
34550                                                                 105   2e-22
25922                                                                  45   4e-04
03831                                                                  42   0.003
20073                                                                  37   0.087
33963                                                                  37   0.090
38751                                                                  35   0.38 
29705                                                                  34   0.47 
08480                                                                  33   1.3  
09654                                                                  33   1.3  
01284                                                                  32   1.8  
25944                                                                  31   4.9  
>31878
          Length = 1178

 Score =  260 bits (664), Expect(2) = 3e-73,   Method: Compositional matrix adjust.
 Identities = 156/365 (42%), Positives = 245/365 (67%), Gaps = 4/365 (1%)
 Frame = -1

Query: 1202 QHFKKRKIQDLAIRCVQKNIKKNKGVKDWPWWKLFTTVRPLIQVQLSEEQIRNKDEEIQQ 1261
            Q  +K ++Q LA+RC+Q+N++K   +++W WWKL+T V+P++ V  +EE++     +++ 
Sbjct: 1088 QKTEKLRVQHLAVRCIQRNVQKYMKIREWSWWKLYTKVKPILNVHRTEEELLEAQADLEA 909

Query: 1262 LRSKLEKVEKERNELRLSSDRLETRISELTSELTDERNTGESASQLLDAETAERLRTEKE 1321
            +++K EK+EKERNE + + ++LE+R+SE+T++L +E  T   AS++L+AE+AER+R EKE
Sbjct: 908  MKTKTEKLEKERNEYKAACEKLESRLSEVTADLMEENMTSTQASEMLEAESAERMRLEKE 729

Query: 1322 MKELQTQYDALKKQXXXXXXXXXXARLIRAAEINGEVDDDDAGGE--WRLKYERAVREVD 1379
            +KELQ +Y  LK+Q          +R+ +A  +  E++DD  GG   ++ + ER +RE+ 
Sbjct: 728  LKELQAKYSPLKRQNEKLQMEVMQSRVWQAQSMEDELEDDVDGGSSVYKERCERLMRELQ 549

Query: 1380 FTKKRLQQELEDKMEVXXXXXXXXXXXXGDLQADSDESQRALQQLKKKCQRLTAELQDTK 1439
             TKK++QQ+ E+ +E              +   +++E +R +Q  KKK QRLTAE+QD K
Sbjct: 548  MTKKQMQQQHEEDLEQELASRKMIEKRLHEAVEEAEEQRRQVQVAKKKTQRLTAEMQDIK 369

Query: 1440 LHLEGQQVRNHELEKKQRRFDSELSQAHEETQREKLQREKLQREKDMLLAEAFSLKQQME 1499
            LHLE Q  RN+ELE+KQRRFD+EL  AHE+ + EK  REKLQRE+D+LL+E +SL+Q ++
Sbjct: 368  LHLEEQMTRNNELERKQRRFDNELGMAHEDVREEKQLREKLQRERDLLLSEKYSLEQSIQ 189

Query: 1500 EKDLDIAGFTQKVVSLEAELQDI--SSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQ 1557
               +D      K   L+ EL DI  S +++ +  SL +VK    +LE KV++QEEELD+Q
Sbjct: 188  NLRMDQQSAADKADRLDKELNDILVSGKDNSEVVSLKRVK---HELELKVREQEEELDDQ 18

Query: 1558 AGSIQ 1562
            AG IQ
Sbjct: 17   AGQIQ 3

 Score = 35.8 bits (81), Expect(2) = 3e-73,   Method: Composition-based stats.
 Identities = 16/30 (53%), Positives = 22/30 (73%)
 Frame = -2

Query: 1173 LARLEEQRDEQTSRHLTLFQAACRGYLARQ 1202
            L++LE  RDE+ +  +T FQA CRGYL R+
Sbjct: 1174 LSQLEAGRDEKLTGIVTQFQALCRGYLGRK 1085
>34550
          Length = 405

 Score =  105 bits (262), Expect = 2e-22,   Method: Composition-based stats.
 Identities = 60/128 (46%), Positives = 83/128 (64%), Gaps = 1/128 (0%)
 Frame = +3

Query: 898  FSYYGPQEGDKKGQSPLLRSSKPRHFLLGHSHGTNWVEYNVAGWLNYTKQNPATQNAPRL 957
            F+ +G Q+  K   S L + S    F+L H+ GT  V+YN AGWL   + NP ++N+  +
Sbjct: 33   FAQHGEQQVRK--DSLLRKGSLGHTFILNHNQGTAPVQYNAAGWLRLCRDNPISKNSIII 206

Query: 958  LQDSQKKIISNLFLGRAGS-ATVLSGSIAGLEGGSQLALRRATSMRKTFTTGMAAVKKKS 1016
            LQDS+   IS LF    GS   ++SGSIAG+EG +  +LRR  SMR+TF +G AA+KKKS
Sbjct: 207  LQDSKSPGISQLFGSLKGSVGGIVSGSIAGMEGTT--SLRRVGSMRRTFMSGTAALKKKS 380

Query: 1017 LCIQIKLQ 1024
            +CIQ+K Q
Sbjct: 381  VCIQVKFQ 404
>25922
          Length = 422

 Score = 44.7 bits (104), Expect = 4e-04,   Method: Composition-based stats.
 Identities = 27/90 (30%), Positives = 47/90 (52%), Gaps = 1/90 (1%)
 Frame = -2

Query: 751 EGMASGLYSELFTLLISLVNRALKSSQHSLCSMM-IVDTPGFQNPEWGGSARGASFEELC 809
           + +   LYS +F+ L+  +N ++K        +M ++D  GF+  E        SFE+  
Sbjct: 319 DALCKALYSRMFSWLVHRINDSIKVRGAQRTKVMGVLDIYGFEVFE------NNSFEQFI 158

Query: 810 HNYAQDRLQRLFHERTFLQELERYKEDNIE 839
            NY  ++LQ++F E T  +E E Y ++ IE
Sbjct: 157 INYCNEKLQQIFIELTLKEEQEEYIKEGIE 68
>03831
          Length = 1143

 Score = 42.0 bits (97), Expect = 0.003,   Method: Composition-based stats.
 Identities = 20/46 (43%), Positives = 29/46 (63%)
 Frame = +3

Query: 262 GTKDLALGLVPGDRLVEINGQNVENKSRDEIVEMIRQSGDSVRLKV 307
           G+   A GL  GDR+VE+NG N+ N++  ++V  I+  GD  RL V
Sbjct: 234 GSPAEAAGLKAGDRIVEVNGTNIGNENHQQVVGRIKAGGDETRLLV 371

 Score = 37.0 bits (84), Expect = 0.080,   Method: Composition-based stats.
 Identities = 14/39 (35%), Positives = 25/39 (64%)
 Frame = +3

Query: 269 GLVPGDRLVEINGQNVENKSRDEIVEMIRQSGDSVRLKV 307
           GL  GDR++E+NG+N+E  +   +++ I+  GD   + V
Sbjct: 702 GLKEGDRIIEVNGENIETTNHTAVIQNIKSRGDKTSMLV 818
>20073
          Length = 582

 Score = 37.0 bits (84), Expect = 0.087,   Method: Composition-based stats.
 Identities = 22/72 (30%), Positives = 40/72 (55%)
 Frame = +3

Query: 259 PGAGTKDLALGLVPGDRLVEINGQNVENKSRDEIVEMIRQSGDSVRLKVQPIPELSELSR 318
           PG G  D    L  GD+L+ +NG +VE +  ++ VE+++ +  SVRL V+  P++ E   
Sbjct: 69  PG-GVADRLNCLKRGDQLLSVNGVSVEGEYHEKAVELLKLAQGSVRLVVRYTPQILEEME 245

Query: 319 SWLRTGEGHRRE 330
           +     +  R++
Sbjct: 246 ARFERQKNSRKQ 281
>33963
          Length = 392

 Score = 37.0 bits (84), Expect = 0.090,   Method: Compositional matrix adjust.
 Identities = 30/102 (29%), Positives = 50/102 (49%)
 Frame = +2

Query: 1424 LKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEETQREKLQREKLQRE 1483
            L+K   RL  EL+D  + +E      + LEKKQR FD  +++   +    + + E  Q+E
Sbjct: 2    LEKAKARLQGELEDLMVDVERSNANANNLEKKQRAFDKTIAEWQAKVNDLQGELENAQKE 181

Query: 1484 KDMLLAEAFSLKQQMEEKDLDIAGFTQKVVSLEAELQDISSQ 1525
                 AE F +K Q+EE         ++  +L  E+ D++ Q
Sbjct: 182  ARGYSAELFRVKAQLEEAVDSTEALRRENKNLADEIHDLTDQ 307
>38751
          Length = 329

 Score = 34.7 bits (78), Expect = 0.38,   Method: Composition-based stats.
 Identities = 21/74 (28%), Positives = 37/74 (50%)
 Frame = +3

Query: 253 VVHFAEPGAGTKDLALGLVPGDRLVEINGQNVENKSRDEIVEMIRQSGDSVRLKVQPIPE 312
           VV+  E G   +   L +  GDR++++NG +  + +  E V ++R + + + + VQP PE
Sbjct: 42  VVYVIEEGCQAEQQGLNI--GDRILDVNGTDFTHLTHAEAVTIMRNAWNVI-MTVQPCPE 212

Query: 313 LSELSRSWLRTGEG 326
                     TG G
Sbjct: 213 SDSGQGQQYTTGRG 254
>29705
          Length = 674

 Score = 34.3 bits (77), Expect = 0.47,   Method: Composition-based stats.
 Identities = 18/60 (30%), Positives = 36/60 (60%)
 Frame = -1

Query: 258 EPGAGTKDLALGLVPGDRLVEINGQNVENKSRDEIVEMIRQSGDSVRLKVQPIPELSELS 317
           E G+  +D  + ++  DRL+ +N  N+E+ + +E V  ++ +GD VRL +     +++LS
Sbjct: 338 EGGSAEQDGRIAVM--DRLLAVNEHNLEDVTHEEAVAALKSTGDVVRLTIAKPTYIADLS 165
>08480
          Length = 698

 Score = 33.1 bits (74), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 15/51 (29%), Positives = 31/51 (60%)
 Frame = -1

Query: 262 GTKDLALGLVPGDRLVEINGQNVENKSRDEIVEMIRQSGDSVRLKVQPIPE 312
           G  DL+  L  GD+++ +N  +VE  + ++  + ++++GD+V +  Q  PE
Sbjct: 698 GPADLSGDLRRGDKILSVNDVDVERATHEQAAQALKRAGDTVEIIAQYKPE 546
>09654
          Length = 1044

 Score = 33.1 bits (74), Expect = 1.3,   Method: Composition-based stats.
 Identities = 15/48 (31%), Positives = 26/48 (54%)
 Frame = -3

Query: 617 HLAENNVFGIVPLSKPEEKQKAAQQFSKLQAAMKVLAISPEEQKTCWL 664
           H ++N  F +    K +  +++  Q  +LQAA +  AIS   Q +CW+
Sbjct: 802 HPSQNAHFKLSRFGKRQRHEQSVHQCPQLQAAGRAQAISSGVQASCWM 659
>01284
          Length = 1603

 Score = 32.3 bits (72), Expect = 1.8,   Method: Compositional matrix adjust.
 Identities = 20/90 (22%), Positives = 38/90 (42%), Gaps = 1/90 (1%)
 Frame = +2

Query: 1090 AQLRGSRLLDAMRMYRQGYPDHMVFSEFRRRF-DVLAPHLTKKHGRNYIVVDEKRAVXXX 1148
            +QL+ + ++  + + +QG+P    FSE    +   L P L++        +D +      
Sbjct: 152  SQLQCAGMVSVLELMQQGFPSRTPFSELYNMYKKYLPPELSR--------LDPRLFCKSL 307

Query: 1149 XXXXXXXXXXCCLGLSRVFFRAGTLARLEE 1178
                         GL++VFFR G  A  ++
Sbjct: 308  FKALGLDDKDFKFGLTKVFFRPGKFAEFDQ 397
>25944
          Length = 417

 Score = 31.2 bits (69), Expect = 4.9,   Method: Compositional matrix adjust.
 Identities = 43/165 (26%), Positives = 72/165 (43%)
 Frame = -3

Query: 1554 LDEQAGSIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEE 1613
            ++E    +Q  E  KLRLE+ M  +R+ +  E+  R+E+ EE+++S  ++L++ME +LE+
Sbjct: 415  IEELEDELQAAEDGKLRLEVNMNALREKYKNEVAGREEQEEESKRSLLRQLREMEAELED 236

Query: 1614 EYEDKQKALREKRELESKLSTLSDQVNQRDFESEKRLRKDLKRTKALLADAQIMLDHLKN 1673
            E   KQ+AL                VN R+                L  D Q M      
Sbjct: 235  ER--KQRAL---------------AVNARN---------------KLQGDVQGM------ 170

Query: 1674 NAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEMEDLHLQIDD 1718
                       + QLE +      AVK  K +  +M+D   +++D
Sbjct: 169  -----------EQQLEMATKVKEDAVKQYKKIFAQMKDFQHELED 68
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6753244|ref|NP_033920.1| calmodulin 1 [Mus musculus]
         (149 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

14594                                                                 269   3e-73
14366                                                                 140   2e-34
22063                                                                 105   9e-34
14945                                                                 105   1e-33
38338                                                                 134   1e-32
05237                                                                 132   4e-32
20251                                                                 117   2e-27
01019                                                                 115   8e-27
26610                                                                 109   5e-25
17484                                                                  83   4e-24
18171                                                                 100   2e-22
06641                                                                  99   6e-22
01491                                                                  68   9e-20
11425                                                                  91   1e-19
16255                                                                  78   1e-15
07385                                                                  72   6e-14
19942                                                                  64   2e-11
08108                                                                  63   4e-11
26019                                                                  62   7e-11
01773                                                                  59   8e-10
22273                                                                  56   6e-09
04067                                                                  51   1e-07
07678                                                                  51   2e-07
15966                                                                  48   1e-06
17892                                                                  48   2e-06
04697                                                                  48   2e-06
19912                                                                  44   2e-05
07198                                                                  44   2e-05
04643                                                                  44   3e-05
26849                                                                  44   4e-05
00167                                                                  43   4e-05
32088                                                                  43   5e-05
05230                                                                  39   0.001
13028                                                                  39   0.001
17977                                                                  38   0.001
03616                                                                  36   0.005
08380                                                                  35   0.010
18677                                                                  35   0.014
35350                                                                  33   0.036
28617                                                                  33   0.048
22490                                                                  32   0.15 
28023                                                                  31   0.22 
01130                                                                  30   0.28 
15239                                                                  28   1.2  
30885                                                                  28   1.4  
12671                                                                  28   2.0  
13551                                                                  27   2.2  
05818                                                                  27   3.8  
33397                                                                  26   5.2  
>14594
          Length = 1014

 Score =  269 bits (688), Expect = 3e-73,   Method: Compositional matrix adjust.
 Identities = 133/145 (91%), Positives = 138/145 (95%)
 Frame = +3

Query: 5   LTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTI 64
           LT+EQ+AEFKEAFSLFDKDGDGTITT ELGTVMRSLGQNPTE ELQDMINEVDADGNGTI
Sbjct: 423 LTDEQVAEFKEAFSLFDKDGDGTITTSELGTVMRSLGQNPTENELQDMINEVDADGNGTI 602

Query: 65  DFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDE 124
           DF EFL MMARKMKDTD EEE+REAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDE
Sbjct: 603 DFEEFLHMMARKMKDTDCEEELREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDE 782

Query: 125 MIREADIDGDGQVNYEEFVQMMTAK 149
           MI+EAD+DGDG VNYEEFV MMTAK
Sbjct: 783 MIKEADLDGDGMVNYEEFVTMMTAK 857
>14366
          Length = 499

 Score =  140 bits (353), Expect = 2e-34,   Method: Compositional matrix adjust.
 Identities = 71/143 (49%), Positives = 103/143 (72%)
 Frame = -3

Query: 4   QLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGT 63
           QL +E   E +EAF + +   D TI   +LG V+RS+G+ PTE++L+ +  E +  G  T
Sbjct: 479 QLRQE---ELQEAF-IMNCSPDNTIALNKLGIVVRSIGRAPTESQLKTLTMEFENRGKRT 312

Query: 64  IDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVD 123
           +   E + ++ +     ++ + +REAFR+FDK+GNG I+AAELRHV+T+LGEKL+DEEVD
Sbjct: 311 LTLQEVIAIVTKYEFAPETSDNLREAFRIFDKEGNGMINAAELRHVLTHLGEKLSDEEVD 132

Query: 124 EMIREADIDGDGQVNYEEFVQMM 146
           EMIREADI GDGQV+Y +FV++M
Sbjct: 131 EMIREADISGDGQVSYNDFVKVM 63
>22063
          Length = 688

 Score =  105 bits (263), Expect(2) = 9e-34,   Method: Compositional matrix adjust.
 Identities = 53/96 (55%), Positives = 69/96 (71%)
 Frame = +3

Query: 4   QLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGT 63
           +LTEEQ  E +EAF LFD DG GTI  KEL   MR+LG  P + E++ MI E+D +G GT
Sbjct: 150 ELTEEQKQEIREAFDLFDADGSGTIDAKELKVAMRALGFEPKKEEIKKMIAEIDKEGTGT 329

Query: 64  IDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNG 99
           IDF +FLT+M +KM + D++EEI +AFR+FD D  G
Sbjct: 330 IDFNDFLTIMTQKMSEKDAKEEILKAFRLFDDDETG 437

 Score = 53.5 bits (127), Expect(2) = 9e-34,   Method: Compositional matrix adjust.
 Identities = 27/46 (58%), Positives = 34/46 (73%)
 Frame = +1

Query: 101 ISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 146
           IS   L+ V   LGE LTDEE+ EMI EAD DGDG++N EEF+++M
Sbjct: 442 ISFRNLKRVAKELGENLTDEELQEMIDEADRDGDGEINQEEFLRIM 579

 Score = 59.7 bits (143), Expect = 5e-10,   Method: Compositional matrix adjust.
 Identities = 30/69 (43%), Positives = 46/69 (66%)
 Frame = +3

Query: 81  DSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYE 140
           + ++EIREAF +FD DG+G I A EL+  M  LG +   EE+ +MI E D +G G +++ 
Sbjct: 162 EQKQEIREAFDLFDADGSGTIDAKELKVAMRALGFEPKKEEIKKMIAEIDKEGTGTIDFN 341

Query: 141 EFVQMMTAK 149
           +F+ +MT K
Sbjct: 342 DFLTIMTQK 368

 Score = 45.8 bits (107), Expect = 6e-06,   Method: Compositional matrix adjust.
 Identities = 22/50 (44%), Positives = 33/50 (66%)
 Frame = +1

Query: 26  GTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMAR 75
             I+ + L  V + LG+N T+ ELQ+MI+E D DG+G I+  EFL +M +
Sbjct: 436 AKISFRNLKRVAKELGENLTDEELQEMIDEADRDGDGEINQEEFLRIMKK 585
>14945
          Length = 1337

 Score =  105 bits (262), Expect(2) = 1e-33,   Method: Compositional matrix adjust.
 Identities = 53/96 (55%), Positives = 69/96 (71%)
 Frame = +1

Query: 4   QLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGT 63
           +LTEEQ  E +EAF LFD DG GTI  KEL   MR+LG  P + E++ MI E+D +G GT
Sbjct: 91  ELTEEQKQEIREAFDLFDADGSGTIDAKELKVAMRALGFEPKKEEIKKMIAEIDKEGTGT 270

Query: 64  IDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNG 99
           IDF +FLT+M +KM + D++EEI +AFR+FD D  G
Sbjct: 271 IDFNDFLTIMTQKMSEKDAKEEILKAFRLFDDDETG 378

 Score = 53.5 bits (127), Expect(2) = 1e-33,   Method: Compositional matrix adjust.
 Identities = 27/46 (58%), Positives = 34/46 (73%)
 Frame = +2

Query: 101 ISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 146
           IS   L+ V   LGE LTDEE+ EMI EAD DGDG++N EEF+++M
Sbjct: 383 ISFRNLKRVAKELGENLTDEELQEMIDEADRDGDGEINQEEFLRIM 520

 Score = 60.5 bits (145), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 30/69 (43%), Positives = 46/69 (66%)
 Frame = +1

Query: 81  DSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYE 140
           + ++EIREAF +FD DG+G I A EL+  M  LG +   EE+ +MI E D +G G +++ 
Sbjct: 103 EQKQEIREAFDLFDADGSGTIDAKELKVAMRALGFEPKKEEIKKMIAEIDKEGTGTIDFN 282

Query: 141 EFVQMMTAK 149
           +F+ +MT K
Sbjct: 283 DFLTIMTQK 309

 Score = 45.8 bits (107), Expect = 6e-06,   Method: Compositional matrix adjust.
 Identities = 22/50 (44%), Positives = 33/50 (66%)
 Frame = +2

Query: 26  GTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMAR 75
             I+ + L  V + LG+N T+ ELQ+MI+E D DG+G I+  EFL +M +
Sbjct: 377 AKISFRNLKRVAKELGENLTDEELQEMIDEADRDGDGEINQEEFLRIMKK 526

 Score = 37.7 bits (86), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 30/90 (33%), Positives = 46/90 (51%), Gaps = 1/90 (1%)
 Frame = +1

Query: 48  ELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELR 107
           E+++  +  DADG+GTID  E    M R +     +EEI++     DK+G G I   +  
Sbjct: 115 EIREAFDLFDADGSGTIDAKELKVAM-RALGFEPKKEEIKKMIAEIDKEGTGTIDFNDFL 291

Query: 108 HVMT-NLGEKLTDEEVDEMIREADIDGDGQ 136
            +MT  + EK   EE+ +  R  D D  G+
Sbjct: 292 TIMTQKMSEKDAKEEILKAFRLFDDDETGK 381
>38338
          Length = 463

 Score =  134 bits (337), Expect = 1e-32,   Method: Compositional matrix adjust.
 Identities = 66/66 (100%), Positives = 66/66 (100%)
 Frame = -2

Query: 1   MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADG 60
           MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADG
Sbjct: 198 MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADG 19

Query: 61  NGTIDF 66
           NGTIDF
Sbjct: 18  NGTIDF 1

 Score = 58.5 bits (140), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 31/72 (43%), Positives = 46/72 (63%), Gaps = 3/72 (4%)
 Frame = -2

Query: 71  TMMARKMKDTDSEEEI---REAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIR 127
           T     M D  +EE+I   +EAF +FDKDG+G I+  EL  VM +LG+  T+ E+ +MI 
Sbjct: 216 THSKSNMADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMIN 37

Query: 128 EADIDGDGQVNY 139
           E D DG+G +++
Sbjct: 36  EVDADGNGTIDF 1
>05237
          Length = 472

 Score =  132 bits (333), Expect = 4e-32,   Method: Compositional matrix adjust.
 Identities = 63/72 (87%), Positives = 71/72 (98%)
 Frame = +3

Query: 78  KDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQV 137
           K+TD+++E+REAFRVFDKDGNG+ISA+ELRHVMTNLGEKLTDEEVDEMIREADIDGDGQV
Sbjct: 9   KETDTDDELREAFRVFDKDGNGFISASELRHVMTNLGEKLTDEEVDEMIREADIDGDGQV 188

Query: 138 NYEEFVQMMTAK 149
           NYEEFV+MMT K
Sbjct: 189 NYEEFVKMMTTK 224

 Score = 66.2 bits (160), Expect = 5e-12,   Method: Compositional matrix adjust.
 Identities = 31/65 (47%), Positives = 45/65 (69%)
 Frame = +3

Query: 12 EFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLT 71
          E +EAF +FDKDG+G I+  EL  VM +LG+  T+ E+ +MI E D DG+G +++ EF+ 
Sbjct: 30 ELREAFRVFDKDGNGFISASELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVK 209

Query: 72 MMARK 76
          MM  K
Sbjct: 210MMTTK 224
>20251
          Length = 2203

 Score =  117 bits (292), Expect = 2e-27,   Method: Compositional matrix adjust.
 Identities = 62/140 (44%), Positives = 91/140 (65%)
 Frame = +3

Query: 7   EEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDF 66
           + QI EFKEAF++ D++ DG I  ++LG ++ SLG+NPTE +L +M+N       G I+F
Sbjct: 147 QSQIQEFKEAFNMIDQNRDGFIDKEDLGDMLASLGKNPTEGQLDEMMNXAP----GPINF 314

Query: 67  PEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMI 126
             FLTM   K+  TD E+ I+ AF  FD+DG G I    LR ++T +G++ TD+EVDEM 
Sbjct: 315 TMFLTMFGDKLNGTDPEDVIKNAFACFDEDGKGVIQEDRLRELLTTMGDRFTDDEVDEMF 494

Query: 127 READIDGDGQVNYEEFVQMM 146
           R+A I   G  +Y EF +++
Sbjct: 495 RDAPIKR-GNFDYLEFTRIL 551

 Score = 39.3 bits (90), Expect = 6e-04,   Method: Compositional matrix adjust.
 Identities = 22/73 (30%), Positives = 41/73 (56%)
 Frame = +3

Query: 77  MKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQ 136
           M D    +E +EAF + D++ +G+I   +L  ++ +LG+  T+ ++DEM+  A     G 
Sbjct: 138 MFDQSQIQEFKEAFNMIDQNRDGFIDKEDLGDMLASLGKNPTEGQLDEMMNXA----PGP 305

Query: 137 VNYEEFVQMMTAK 149
           +N+  F+ M   K
Sbjct: 306 INFTMFLTMFGDK 344
>01019
          Length = 1705

 Score =  115 bits (288), Expect = 8e-27,   Method: Compositional matrix adjust.
 Identities = 55/58 (94%), Positives = 57/58 (98%)
 Frame = +1

Query: 92  VFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK 149
           VFDKDGNG+ISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFV MMT+K
Sbjct: 43  VFDKDGNGFISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVTMMTSK 216

 Score = 59.3 bits (142), Expect = 6e-10,   Method: Compositional matrix adjust.
 Identities = 28/58 (48%), Positives = 41/58 (70%)
 Frame = +1

Query: 19  LFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARK 76
           +FDKDG+G I+  EL  VM +LG+  T+ E+ +MI E D DG+G +++ EF+TMM  K
Sbjct: 43  VFDKDGNGFISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVTMMTSK 216
>26610
          Length = 455

 Score =  109 bits (272), Expect = 5e-25,   Method: Compositional matrix adjust.
 Identities = 48/133 (36%), Positives = 91/133 (68%)
 Frame = +3

Query: 15  EAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMA 74
           EAF LFD D DG I   E+GT +RSLG   T+++L+ ++++   + +G +D   F   + 
Sbjct: 54  EAFELFDTDNDGKIAASEVGTAIRSLGHVVTDSDLRRLLSKAGIEPHGKVDMNRF-RQLV 230

Query: 75  RKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGD 134
           + ++  +  +++ EAF   DK+G+G++ A ELRH++T++G+++TDEE + ++ E ++D +
Sbjct: 231 QPLQGVNYTKQLDEAFNTIDKEGSGFVMATELRHLLTHMGDRITDEEFNALLEELEVDSN 410

Query: 135 GQVNYEEFVQMMT 147
           G+V  +EFVQ+++
Sbjct: 411 GRVRRKEFVQLLS 449

 Score = 46.6 bits (109), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 21/65 (32%), Positives = 42/65 (64%)
 Frame = +3

Query: 82  SEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEE 141
           S++ + EAF +FD D +G I+A+E+   + +LG  +TD ++  ++ +A I+  G+V+   
Sbjct: 36  SKDAVSEAFELFDTDNDGKIAASEVGTAIRSLGHVVTDSDLRRLLSKAGIEPHGKVDMNR 215

Query: 142 FVQMM 146
           F Q++
Sbjct: 216 FRQLV 230

 Score = 42.4 bits (98), Expect = 7e-05,   Method: Compositional matrix adjust.
 Identities = 19/64 (29%), Positives = 36/64 (56%)
 Frame = +3

Query: 12  EFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLT 71
           +  EAF+  DK+G G +   EL  ++  +G   T+ E   ++ E++ D NG +   EF+ 
Sbjct: 261 QLDEAFNTIDKEGSGFVMATELRHLLTHMGDRITDEEFNALLEELEVDSNGRVRRKEFVQ 440

Query: 72  MMAR 75
           +++R
Sbjct: 441 LLSR 452
>17484
          Length = 471

 Score = 82.8 bits (203), Expect(2) = 4e-24,   Method: Compositional matrix adjust.
 Identities = 38/83 (45%), Positives = 61/83 (73%), Gaps = 1/83 (1%)
 Frame = -3

Query: 68  EFLTMMARKMKD-TDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMI 126
           EFL ++  +MK  ++ ++E+R+AFR FD++G+G IS +ELR  M  +G+KL+D +V+ +I
Sbjct: 322 EFLPLIVGRMKGGSEKDKEMRDAFRAFDQNGDGVISISELRQAMAKMGQKLSDADVESII 143

Query: 127 READIDGDGQVNYEEFVQMMTAK 149
           R+ D DGDG VNYEEF + +  +
Sbjct: 142 RDVDKDGDGFVNYEEFTKFIAGQ 74

 Score = 44.7 bits (104), Expect(2) = 4e-24,   Method: Compositional matrix adjust.
 Identities = 19/47 (40%), Positives = 31/47 (65%)
 Frame = -1

Query: 20  FDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDF 66
           +D+DG+G IT  E  +V+R LG + +E EL++M+   D D +G I+ 
Sbjct: 465 YDQDGNGKITRNEFRSVVRMLGHSLSEKELEEMMQAADTDASGAIEL 325

 Score = 55.8 bits (133), Expect = 6e-09,   Method: Compositional matrix adjust.
 Identities = 25/67 (37%), Positives = 44/67 (65%)
 Frame = -3

Query: 8   EQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFP 67
           E+  E ++AF  FD++GDG I+  EL   M  +GQ  ++A+++ +I +VD DG+G +++ 
Sbjct: 280 EKDKEMRDAFRAFDQNGDGVISISELRQAMAKMGQKLSDADVESIIRDVDKDGDGFVNYE 101

Query: 68  EFLTMMA 74
           EF   +A
Sbjct: 100 EFTKFIA 80

 Score = 43.9 bits (102), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 19/45 (42%), Positives = 31/45 (68%)
 Frame = -1

Query: 93  FDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQV 137
           +D+DGNG I+  E R V+  LG  L+++E++EM++ AD D  G +
Sbjct: 465 YDQDGNGKITRNEFRSVVRMLGHSLSEKELEEMMQAADTDASGAI 331
>18171
          Length = 1131

 Score =  100 bits (249), Expect = 2e-22,   Method: Compositional matrix adjust.
 Identities = 49/98 (50%), Positives = 70/98 (71%), Gaps = 3/98 (3%)
 Frame = +3

Query: 52  MINEVDADGNGTIDFPEFLTMMARKMKDTDSEEE---IREAFRVFDKDGNGYISAAELRH 108
           +I++V     G +DFP+FLT+MAR +   D +EE   + EA  + DKD  G IS A LRH
Sbjct: 60  LIHDVSNSNQGKVDFPDFLTLMARTVGSKDPQEEDDAMLEALTLLDKDQTGVISTALLRH 239

Query: 109 VMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 146
           V+T LG++LT EEV+E+I+EAD +  GQV+Y+EF++MM
Sbjct: 240 VLTTLGDQLTSEEVEELIKEADKEETGQVDYKEFIKMM 353
>06641
          Length = 726

 Score = 99.0 bits (245), Expect = 6e-22,   Method: Compositional matrix adjust.
 Identities = 52/138 (37%), Positives = 84/138 (60%), Gaps = 5/138 (3%)
 Frame = +1

Query: 16  AFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEV-DADGNGTIDFPEFLTMMA 74
           AF +FD + + T+  +E+GT++RSLG  P+EAEL DM+ E+ + +  G I F +FL MM 
Sbjct: 208 AFDIFDHEANKTVDVREVGTIIRSLGCCPSEAELHDMLAEIEEEEPTGYIRFEKFLPMMT 387

Query: 75  RKMKDTD----SEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREAD 130
           + + +       E++I +AF+V D +G GY+   EL   MT  GE  T EE++EM+ +A 
Sbjct: 388 KVLMERRYKAVPEDQIVKAFQVLDVEGRGYLLQEELSKYMTEEGEPFTSEELEEMMSQAL 567

Query: 131 IDGDGQVNYEEFVQMMTA 148
               G + Y+++  +M A
Sbjct: 568 DPEKGYIPYKDYASLMAA 621
>01491
          Length = 1707

 Score = 68.2 bits (165), Expect(2) = 9e-20,   Method: Compositional matrix adjust.
 Identities = 39/99 (39%), Positives = 62/99 (62%)
 Frame = +1

Query: 50  QDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHV 109
           ++  + VD D  G I + +F  +   K+ + + E E+REAFRV DK   G I   +LR +
Sbjct: 244 EEWADAVDEDAAGFITWEQFKPVFELKLHEDEDEREMREAFRVLDKGNKGVIPVEDLRWL 423

Query: 110 MTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTA 148
           + +LG+ LT++E+++MI E D DG G V+YEEF  +M +
Sbjct: 424 LKSLGDDLTEDEIEDMIVETDTDGSGTVDYEEFRTLMNS 540

 Score = 44.3 bits (103), Expect(2) = 9e-20,   Method: Compositional matrix adjust.
 Identities = 19/38 (50%), Positives = 27/38 (71%)
 Frame = +2

Query: 4   QLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLG 41
           Q+TE+   +  + F LFDK G+GT++TKEL  V +SLG
Sbjct: 107 QITEKMYNDASQTFHLFDKKGNGTVSTKELANVFKSLG 220

 Score = 57.0 bits (136), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 27/58 (46%), Positives = 40/58 (68%)
 Frame = +1

Query: 16  AFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMM 73
           AF + DK   G I  ++L  +++SLG + TE E++DMI E D DG+GT+D+ EF T+M
Sbjct: 361 AFRVLDKGNKGVIPVEDLRWLLKSLGDDLTEDEIEDMIVETDTDGSGTVDYEEFRTLM 534

 Score = 35.4 bits (80), Expect = 0.009,   Method: Compositional matrix adjust.
 Identities = 15/35 (42%), Positives = 24/35 (68%)
 Frame = +2

Query: 88  EAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEV 122
           + F +FDK GNG +S  EL +V  +LG ++ DE++
Sbjct: 140 QTFHLFDKKGNGTVSTKELANVFKSLGLQVEDEKL 244
>11425
          Length = 599

 Score = 91.3 bits (225), Expect = 1e-19,   Method: Compositional matrix adjust.
 Identities = 60/150 (40%), Positives = 87/150 (58%), Gaps = 9/150 (6%)
 Frame = -2

Query: 4   QLTEEQIAEFKEAFSLFD-KDG-DGTITTKELGTVMRSLGQNPTEAELQDMINEVDAD-- 59
            L++  I +  E F LFD  DG DG +   ++G +   LG NPT    Q++I +      
Sbjct: 580 SLSKSDIEDITEVFELFDFWDGRDGDVDAFKVGDMCFCLGLNPT----QEIIRKNGGTTK 413

Query: 60  -GNGTIDFPEFLTMM--ARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEK 116
            G       EFL +     K KDT +  +  E F+ FD++G G+ISAAELRH++T LGE+
Sbjct: 412 LGEKAYKLEEFLPIYETISKEKDTGTFADFMEGFKTFDREGQGFISAAELRHLLTGLGER 233

Query: 117 LTDEEVDEMIREADI--DGDGQVNYEEFVQ 144
           L+D+EVDE+I+  D   D +G V YE+F+Q
Sbjct: 232 LSDDEVDELIKATDTREDLEGNVKYEDFIQ 143
>16255
          Length = 767

 Score = 78.2 bits (191), Expect = 1e-15,   Method: Compositional matrix adjust.
 Identities = 38/40 (95%), Positives = 39/40 (97%)
 Frame = -2

Query: 110 MTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK 149
           MTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFV MMT+K
Sbjct: 766 MTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVTMMTSK 647

 Score = 41.2 bits (95), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 18/40 (45%), Positives = 28/40 (70%)
 Frame = -2

Query: 37  MRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARK 76
           M +LG+  T+ E+ +MI E D DG+G +++ EF+TMM  K
Sbjct: 766 MTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVTMMTSK 647
>07385
          Length = 1292

 Score = 72.4 bits (176), Expect = 6e-14,   Method: Compositional matrix adjust.
 Identities = 37/49 (75%), Positives = 40/49 (81%)
 Frame = +3

Query: 101 ISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK 149
           ISA +LR       +KLTDEEVDEMIREADIDGDGQVNYEEFV+MMT K
Sbjct: 114 ISAGQLRGARF---QKLTDEEVDEMIREADIDGDGQVNYEEFVKMMTTK 251
>19942
          Length = 367

 Score = 64.3 bits (155), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 31/32 (96%), Positives = 32/32 (100%)
 Frame = +2

Query: 109 VMTNLGEKLTDEEVDEMIREADIDGDGQVNYE 140
           VMTNLGEKLTDEEVDEMIREADIDGDGQVNY+
Sbjct: 2   VMTNLGEKLTDEEVDEMIREADIDGDGQVNYD 97
>08108
          Length = 818

 Score = 63.2 bits (152), Expect = 4e-11,   Method: Compositional matrix adjust.
 Identities = 42/139 (30%), Positives = 72/139 (51%), Gaps = 4/139 (2%)
 Frame = +2

Query: 11  AEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFL 70
           AE + AF++FD DG G+I+  ELG  +R+ G + T+ +  ++I + D+D NG ID  EF 
Sbjct: 125 AECQTAFAVFDTDGSGSISAGELGEALRAQGADITDDQTAELIKKYDSDSNGDIDTDEF- 301

Query: 71  TMMARKMKDTDSE----EEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMI 126
               RK+ + +S+     +    F+  D DG+G I+A+E+           TD +   M+
Sbjct: 302 ----RKLVEGESDVARLAQSALMFKSLDADGDGQITASEITEAQGKKTIGATDGQFAAMV 469

Query: 127 READIDGDGQVNYEEFVQM 145
             A     G + +  F++ 
Sbjct: 470 EAA---AGGVLTFAAFLKC 517

 Score = 52.8 bits (125), Expect = 6e-08,   Method: Compositional matrix adjust.
 Identities = 24/65 (36%), Positives = 42/65 (64%)
 Frame = +2

Query: 82  SEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEE 141
           ++ E + AF VFD DG+G ISA EL   +   G  +TD++  E+I++ D D +G ++ +E
Sbjct: 119 TDAECQTAFAVFDTDGSGSISAGELGEALRAQGADITDDQTAELIKKYDSDSNGDIDTDE 298

Query: 142 FVQMM 146
           F +++
Sbjct: 299 FRKLV 313

 Score = 38.9 bits (89), Expect = 8e-04,   Method: Compositional matrix adjust.
 Identities = 28/105 (26%), Positives = 46/105 (43%)
 Frame = +2

Query: 45  TEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAA 104
           T+AE Q      D DG+G+I   E    +  +  D  ++++  E  + +D D NG I   
Sbjct: 119 TDAECQTAFAVFDTDGSGSISAGELGEALRAQGADI-TDDQTAELIKKYDSDSNGDIDTD 295

Query: 105 ELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK 149
           E R ++    +     +   M +  D DGDGQ+   E  +    K
Sbjct: 296 EFRKLVEGESDVARLAQSALMFKSLDADGDGQITASEITEAQGKK 430
>26019
          Length = 1561

 Score = 62.4 bits (150), Expect = 7e-11,   Method: Compositional matrix adjust.
 Identities = 37/111 (33%), Positives = 63/111 (56%), Gaps = 1/111 (0%)
 Frame = +2

Query: 17  FSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARK 76
           F   D D  G+++  E  + +  L QNP    +Q +I+  D DGNG +DF EF+  +++ 
Sbjct: 116 FRKLDLDNSGSLSIDEFMS-LPELQQNPL---VQRVIDIFDTDGNGEVDFKEFIEGISQF 283

Query: 77  MKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNL-GEKLTDEEVDEMI 126
               D E ++R AF+++D D +GYIS  EL  V+  + G  L D ++ +++
Sbjct: 284 SVKGDKESKLRFAFKIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIV 436

 Score = 29.3 bits (64), Expect = 0.70,   Method: Compositional matrix adjust.
 Identities = 18/61 (29%), Positives = 33/61 (54%)
 Frame = +2

Query: 84  EEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFV 143
           + + + FR  D D +G +S  E      +L E   +  V  +I   D DG+G+V+++EF+
Sbjct: 98  QRLGKRFRKLDLDNSGSLSIDEF----MSLPELQQNPLVQRVIDIFDTDGNGEVDFKEFI 265

Query: 144 Q 144
           +
Sbjct: 266 E 268
>01773
          Length = 1950

 Score = 58.9 bits (141), Expect = 8e-10,   Method: Compositional matrix adjust.
 Identities = 39/142 (27%), Positives = 71/142 (50%), Gaps = 7/142 (4%)
 Frame = +1

Query: 13  FKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDAD-GNGTIDFPEF-- 69
           +K+ F   DK+ DG +  KEL  + +  G + +++++ D     D   G+  I F  F  
Sbjct: 160 YKQLFKEADKNNDGYLEIKELRELFKRNGSSLSDSQIADTFVFFDGPRGDKRITFEXFCK 339

Query: 70  ----LTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEM 125
               + M  +K+          E F+  DK G+GY+   EL+ ++   G+K T ++V  +
Sbjct: 340 GLDQIVMFVQKLA---------ELFKAKDKSGDGYLDRDELKALLDESGQKFTADDVSAI 492

Query: 126 IREADIDGDGQVNYEEFVQMMT 147
           ++ AD + D ++ +EEFV   T
Sbjct: 493 LKSADKNNDNKICFEEFVDACT 558

 Score = 33.1 bits (74), Expect = 0.048,   Method: Compositional matrix adjust.
 Identities = 21/78 (26%), Positives = 40/78 (51%), Gaps = 2/78 (2%)
 Frame = +1

Query: 71  TMMARKMKDT-DSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEV-DEMIRE 128
           + MA K K T  + +  ++ F+  DK+ +GY+   ELR +    G  L+D ++ D  +  
Sbjct: 112 SKMAAKGKGTGPNTDAYKQLFKEADKNNDGYLEIKELRELFKRNGSSLSDSQIADTFVFF 291

Query: 129 ADIDGDGQVNYEEFVQMM 146
               GD ++ +E F + +
Sbjct: 292 DGPRGDKRITFEXFCKGL 345
>22273
          Length = 297

 Score = 55.8 bits (133), Expect = 6e-09,   Method: Compositional matrix adjust.
 Identities = 26/28 (92%), Positives = 27/28 (96%)
 Frame = +1

Query: 122 VDEMIREADIDGDGQVNYEEFVQMMTAK 149
           VDEMIREADIDGDGQVNYEEFV+MMT K
Sbjct: 1   VDEMIREADIDGDGQVNYEEFVKMMTTK 84
>04067
          Length = 1920

 Score = 51.2 bits (121), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 24/55 (43%), Positives = 37/55 (67%)
 Frame = -1

Query: 19   LFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMM 73
            + DK   G I  ++L  +++SLG + TE E++DMI E D DG+GT+D+ EF  +M
Sbjct: 1920 VLDKGNKGVIPVEDLRWLLKSLGDDLTEDEIEDMILETDTDGSGTVDYEEFYKLM 1756
>07678
          Length = 958

 Score = 51.2 bits (121), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 42/143 (29%), Positives = 67/143 (46%), Gaps = 10/143 (6%)
 Frame = +1

Query: 10  IAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAE-LQDMINEVDADGNGTIDFPE 68
           I      F + D DG+ ++  KE    +   G    E + +Q+M    D D +GTIDF E
Sbjct: 316 IKGLARKFKIMDDDGNRSLDFKEFKKGITEFGLTQFEGDVIQEMFTCFDKDZSGTIDFDE 495

Query: 69  FLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHV--MTNLGEKLTDEEVDEMI 126
           FL  +   M     ++ I+ AF+  DK G+G ++  +L+ V  +T   + L  E  +E I
Sbjct: 496 FLVKLRPPMSQM-RKDLIQRAFQKLDKTGDGVVTVEDLKGVYNVTKHPKYLNGEWTEERI 672

Query: 127 READIDG-------DGQVNYEEF 142
               +D        DG++  EEF
Sbjct: 673 LRIFLDSFDSPNDKDGKITKEEF 741
>15966
          Length = 362

 Score = 48.1 bits (113), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 30/100 (30%), Positives = 51/100 (51%), Gaps = 6/100 (6%)
 Frame = +2

Query: 56  VDADGNGTIDFPEF------LTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHV 109
           V + G+  I F EF      + M  +K+          E F+  DK G+GY+   EL+ +
Sbjct: 59  VPSCGDKRITFEEFCKGLDQIVMFVQKLA---------ELFKAKDKSGDGYLDRDELKAL 211

Query: 110 MTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK 149
           +   G+K T ++V  +++ AD + D ++ +EEFV   T K
Sbjct: 212 LDESGQKFTADDVSAILKSADKNNDNKICFEEFVDACT*K 331
>17892
          Length = 512

 Score = 47.8 bits (112), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 21/60 (35%), Positives = 41/60 (68%), Gaps = 1/60 (1%)
 Frame = +1

Query: 90  FRVFDKDGNGYISAAELRHVMTNLGEK-LTDEEVDEMIREADIDGDGQVNYEEFVQMMTA 148
           F + DKD  GY+S  ++R  + N G+  ++ E++ ++++E D + +GQV  +E++QMM+A
Sbjct: 1   FELIDKDKKGYVSINDIRRALKNFGDGDVSGEQLHDILKEIDTNMNGQVELDEYLQMMSA 180
>04697
          Length = 559

 Score = 47.8 bits (112), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 21/69 (30%), Positives = 38/69 (55%)
 Frame = +1

Query: 5   LTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTI 64
            T+++I ++ + F   D    G +T  +L    + +G+  TE +L D+++EVD   N  +
Sbjct: 343 FTKDEINQYVKRFKSLDYQNKGFVTVNDLRRYFKKMGEKVTEDQLHDILSEVDLSRNAQV 522

Query: 65  DFPEFLTMM 73
           D  EFL +M
Sbjct: 523 DLGEFLQLM 549
>19912
          Length = 865

 Score = 44.3 bits (103), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 27/75 (36%), Positives = 39/75 (52%), Gaps = 1/75 (1%)
 Frame = +2

Query: 70  LTMMARKMKDTDSEE-EIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIRE 128
           L  M + M   DS    + + F  FDK+G   I+  + R  +T     L  +EVD ++ E
Sbjct: 623 LHPMVKLMAYIDSNNLRLVDFFNKFDKEGTMSITRDQFRQGLTEASIPLAGDEVDFLLDE 802

Query: 129 ADIDGDGQVNYEEFV 143
            D DGDG++NY E V
Sbjct: 803 LDRDGDGEINYSELV 847
>07198
          Length = 1675

 Score = 44.3 bits (103), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 35/137 (25%), Positives = 68/137 (49%)
 Frame = -3

Query: 8   EQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFP 67
           E + E ++ F   D + DG++ +KE       +  +  + EL+  + + D + +GTI   
Sbjct: 491 ELVDEDRKVFDAADANKDGSLNSKEYFAFF--MPNSFPQLELERFMRQSDKNKDGTISME 318

Query: 68  EFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIR 127
           EF+   A     T SE    E+F+ +DKD +G +S  E    +    ++  D EV+ +  
Sbjct: 317 EFMPEGATGDTRTSSE----ESFKNYDKDKDGSLSLEEAMEWINPSSDEHADVEVEHLFT 150

Query: 128 EADIDGDGQVNYEEFVQ 144
             D++ DG+++ +E + 
Sbjct: 149 IGDVNHDGKLSKDEILN 99
>04643
          Length = 1881

 Score = 43.9 bits (102), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 18/52 (34%), Positives = 36/52 (69%), Gaps = 1/52 (1%)
 Frame = +2

Query: 98  NGYISAAELR-HVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTA 148
           +G + A E++ HV    G+ +++E +D ++ ++D DG+G++NY+EF+   TA
Sbjct: 2   SGCLCADEIKAHVRALTGDDMSEEALDNLVSKSDADGNGKINYKEFLASWTA 157

 Score = 37.4 bits (85), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 17/47 (36%), Positives = 30/47 (63%), Gaps = 1/47 (2%)
 Frame = +2

Query: 26 GTITTKELGTVMRSL-GQNPTEAELQDMINEVDADGNGTIDFPEFLT 71
          G +   E+   +R+L G + +E  L +++++ DADGNG I++ EFL 
Sbjct: 5  GCLCADEIKAHVRALTGDDMSEEALDNLVSKSDADGNGKINYKEFLA 145
>26849
          Length = 649

 Score = 43.5 bits (101), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 23/65 (35%), Positives = 35/65 (53%)
 Frame = +2

Query: 10  IAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEF 69
           I     AF + DKDG   ++ +E    +  +  +  EA+++DM    D DGNGTI+  EF
Sbjct: 164 ILGLARAFRVMDKDGSKVLSLEEFKKGILDMHIDINEADIEDMFYRFDNDGNGTINMTEF 343

Query: 70  LTMMA 74
           L  +A
Sbjct: 344 LLKVA 358

 Score = 38.1 bits (87), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 18/58 (31%), Positives = 34/58 (58%)
 Frame = +2

Query: 86  IREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFV 143
           +  AFRV DKDG+  +S  E +  + ++   + + ++++M    D DG+G +N  EF+
Sbjct: 173 LARAFRVMDKDGSKVLSLEEFKKGILDMHIDINEADIEDMFYRFDNDGNGTINMTEFL 346
>00167
          Length = 2176

 Score = 43.1 bits (100), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 24/62 (38%), Positives = 36/62 (58%)
 Frame = +3

Query: 45  TEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAA 104
           T  EL ++    D DG GT+DF EFL  +  KM +    + +++AF   DK G+G I+A 
Sbjct: 834 TSEELNEVFRRFDKDGTGTLDFEEFLLALRPKMNEF-RRKLVKKAFAKMDKTGDGIITAD 1010

Query: 105 EL 106
           +L
Sbjct: 1011DL 1016
>32088
          Length = 1928

 Score = 43.1 bits (100), Expect = 5e-05,   Method: Composition-based stats.
 Identities = 22/64 (34%), Positives = 33/64 (51%)
 Frame = +1

Query: 79  DTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVN 138
           D D   E+R  F   D D NG+IS  EL      +G  +   E+  ++ + D  GDG++N
Sbjct: 928 DEDQLTELRSVFDSIDDDNNGHISXGELDSAFRAVGLNIPGYELRTIMSKYDASGDGRLN 1107

Query: 139 YEEF 142
            +EF
Sbjct: 1108MDEF 1119
>05230
          Length = 843

 Score = 38.5 bits (88), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 35/124 (28%), Positives = 63/124 (50%), Gaps = 3/124 (2%)
 Frame = -2

Query: 25  DGTITTKELGTVMRSLG-QNPTEAE--LQDMINEVDADGNGTIDFPEFLTMMARKMKDTD 81
           DG +   E   +M  LG  N  EA   L D   +V+ D    +   E++++M+    D  
Sbjct: 815 DGRLNLFEFTRLMTLLGLPNAQEAAKVLFDKQTKVERD---RLRMEEYISIMSDASVDMK 645

Query: 82  SEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEE 141
           +    R+ F  FD DG+G+ S  ++   + N+G  +T  ++   I+  D + DG++NY +
Sbjct: 644 TNM-WRKLFAQFDTDGSGWASREDVIEGLENIGITIT-PDLRAKIKAMDGNKDGKINYAD 471

Query: 142 FVQM 145
           F++M
Sbjct: 470 FLRM 459
>13028
          Length = 1273

 Score = 38.5 bits (88), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 31/110 (28%), Positives = 51/110 (46%), Gaps = 10/110 (9%)
 Frame = -1

Query: 27   TITTKELGTVMRSLGQNPTEAELQDMINEVDAD-----GNGT--IDFPEFLTMMARKMKD 79
            TI   E+  VMR+LG  PTE E++DM+NEV        G     +D   F+ +       
Sbjct: 1063 TIPLSEVPFVMRALGFYPTEQEIEDMLNEVKFSRYVETGQYVEELDLGTFIKLYVNHRPA 884

Query: 80   TD-SEEEIREAFRVF--DKDGNGYISAAELRHVMTNLGEKLTDEEVDEMI 126
               S ++++ AF          G +   EL  ++ + GE +T+ E+ E +
Sbjct: 883  FGLSPDKLQWAFDTLGMPSPAGGAVDRGELLDILQSKGEHMTEYELAEYL 734
>17977
          Length = 445

 Score = 38.1 bits (87), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 22/82 (26%), Positives = 40/82 (48%), Gaps = 2/82 (2%)
 Frame = +3

Query: 70  LTMMARKMK--DTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIR 127
           +  M +++K  +  S  ++  AFR +DKDG G I   +LR         +    ++++  
Sbjct: 171 VAAMRQQLKKFNYHSFPDLIRAFRFYDKDGKGKIDIDDLREACRKFDVPIDVWLLEQVFD 350

Query: 128 EADIDGDGQVNYEEFVQMMTAK 149
             D + DGQ++Y EF   +  K
Sbjct: 351 YCDENRDGQIDYLEFANFLNWK 416
>03616
          Length = 2372

 Score = 36.2 bits (82), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 18/68 (26%), Positives = 39/68 (57%)
 Frame = +2

Query: 75  RKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGD 134
           +K+  TD +  + E F  +D+D  GYIS   +R +   L   + D+ +  ++++  +D +
Sbjct: 857 KKIAITD-KSRVDEMFLRYDRDRTGYISVENMRDLCRRLQLPVDDDVILALVQQCTMDQE 1033

Query: 135 GQVNYEEF 142
           G+++ E+F
Sbjct: 1034GRISLEDF 1057
>08380
          Length = 1236

 Score = 35.4 bits (80), Expect = 0.010,   Method: Compositional matrix adjust.
 Identities = 43/160 (26%), Positives = 72/160 (45%), Gaps = 28/160 (17%)
 Frame = -1

Query: 11  AEFKEAFSLFDKDGDGTITTKEL-GTVMRSLGQNPTEA--ELQDMINEVDADGNGTIDFP 67
           ++ K+     D D DG ++  EL   V   + ++ +EA  E +++   +D D NG + + 
Sbjct: 885 SKLKDIVYKVDSDKDGKLSVAELEAWVKDKMEEHFSEATQENEEIFKHLDPDNNGKVHWK 706

Query: 68  EFLT--MMARKMK----------------DTDSEEEI-REAFRVFDKDG---NGYISAAE 105
           E+    ++A+  K                D D++EEI R  FR  D DG   +  ++  E
Sbjct: 705 EYYVHFLLAKGYKQDVASRHVVDYDZIQLDPDAKEEIIRYKFRWSDADGEPMDNELTREE 526

Query: 106 L---RHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEF 142
               RH      EK  +  V+ ++   D +GDG V  EEF
Sbjct: 525 FMSFRH--PEQSEKTLNNMVNGILGGIDTNGDGVVTEEEF 412
>18677
          Length = 754

 Score = 34.7 bits (78), Expect = 0.014,   Method: Compositional matrix adjust.
 Identities = 22/74 (29%), Positives = 35/74 (47%)
 Frame = +2

Query: 2   ADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGN 61
           A +L +E I  ++E F  FDK+  G + T ELG +   LG   T   L  ++     D  
Sbjct: 482 AKRLWKE-IKAYREVFLQFDKNRSGLVDTYELGNMFSKLGFPVTRPVLTSIVRRY-GDRR 655

Query: 62  GTIDFPEFLTMMAR 75
             I   +F+ ++ R
Sbjct: 656 NQISLEDFVVVILR 697
>35350
          Length = 339

 Score = 33.5 bits (75), Expect = 0.036,   Method: Compositional matrix adjust.
 Identities = 20/45 (44%), Positives = 25/45 (55%)
 Frame = +2

Query: 32 ELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARK 76
          EL  +M  LG   T   L+ MI EVD D +  I F EFL ++ RK
Sbjct: 11 ELKYMMEKLGAPQTHLGLKKMIAEVDEDHDSKISFREFL-LIYRK 142
>28617
          Length = 348

 Score = 33.1 bits (74), Expect = 0.048,   Method: Compositional matrix adjust.
 Identities = 12/23 (52%), Positives = 20/23 (86%)
 Frame = -2

Query: 124 EMIREADIDGDGQVNYEEFVQMM 146
           EM+ EAD++GDGQ++  EF+++M
Sbjct: 338 EMVEEADVNGDGQIDQSEFIRIM 270

 Score = 26.2 bits (56), Expect = 5.5,   Method: Compositional matrix adjust.
 Identities = 10/25 (40%), Positives = 17/25 (68%)
 Frame = -2

Query: 49  LQDMINEVDADGNGTIDFPEFLTMM 73
            ++M+ E D +G+G ID  EF+ +M
Sbjct: 344 WREMVEEADVNGDGQIDQSEFIRIM 270
>22490
          Length = 743

 Score = 31.6 bits (70), Expect = 0.15,   Method: Compositional matrix adjust.
 Identities = 13/23 (56%), Positives = 19/23 (82%)
 Frame = -1

Query: 122 VDEMIREADIDGDGQVNYEEFVQ 144
           VDE++RE D+D DG V+Y EF++
Sbjct: 467 VDEILREDDLDKDGYVDYTEFMK 399
>28023
          Length = 475

 Score = 30.8 bits (68), Expect = 0.22,   Method: Compositional matrix adjust.
 Identities = 14/30 (46%), Positives = 21/30 (70%)
 Frame = -1

Query: 118 TDEEVDEMIREADIDGDGQVNYEEFVQMMT 147
           TD+EVDE+I   D + DG+V++ EF + M 
Sbjct: 475 TDQEVDEVIDYIDKNKDGKVDFSEFYKFMV 386
>01130
          Length = 1032

 Score = 30.4 bits (67), Expect = 0.28,   Method: Compositional matrix adjust.
 Identities = 15/54 (27%), Positives = 28/54 (51%)
 Frame = +3

Query: 90  FRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFV 143
           FR  D  G G++     RHV      +LT + + ++   +D+  DG+++ +EF 
Sbjct: 549 FRALDVQGKGFLDGDCCRHVFE--ASELTSDVLSDVWNLSDVTRDGKLDVDEFC 704
>15239
          Length = 913

 Score = 28.5 bits (62), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 17/58 (29%), Positives = 33/58 (56%), Gaps = 1/58 (1%)
 Frame = +2

Query: 87  REAFRVF-DKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFV 143
           R+ F+ F DK+ +G + A E+R  +       +  E   +I ++D D DG+++Y+E +
Sbjct: 20  RDQFQQFRDKNNDGKLDANEVREWIIPDDYDHSSAEAKHLIGDSDGDKDGKLSYDEIL 193
>30885
          Length = 1090

 Score = 28.1 bits (61), Expect = 1.4,   Method: Compositional matrix adjust.
 Identities = 16/59 (27%), Positives = 30/59 (50%)
 Frame = -1

Query: 86  IREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQ 144
           ++  F+ FD+  NG+I+  +    +T L   ++  E+  +  EA    D  VNY  F++
Sbjct: 793 LKPVFQDFDRHNNGHITRVQFSQGLTMLEIPISTPELAAL--EARFYNDVGVNYLAFLK 623
>12671
          Length = 807

 Score = 27.7 bits (60), Expect = 2.0,   Method: Compositional matrix adjust.
 Identities = 14/60 (23%), Positives = 30/60 (50%)
 Frame = -2

Query: 90  FRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK 149
           +R  DKDG G +   +L   +      L  E ++++    D DG+ +++Y  F++ +  +
Sbjct: 797 YRQLDKDGTGILLQHDLERGLLRFHVDLPPEVLEQVFEIVDPDGERRLDYSFFMRTVLGQ 618
>13551
          Length = 529

 Score = 27.3 bits (59), Expect = 2.2,   Method: Compositional matrix adjust.
 Identities = 12/37 (32%), Positives = 23/37 (62%)
 Frame = +1

Query: 113 LGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK 149
           +GE + + +V + +RE D + DG +++EEF  +   K
Sbjct: 55  MGEIVNEVKVTQWLREEDKNVDGCLDFEEFCALYKKK 165
>05818
          Length = 1203

 Score = 26.6 bits (57), Expect = 3.8,   Method: Compositional matrix adjust.
 Identities = 14/36 (38%), Positives = 18/36 (50%)
 Frame = +1

Query: 41  GQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARK 76
           G  PT    Q ++NEV+A      D   FLT+M  K
Sbjct: 712 GMIPTR---QKLVNEVEASARSLTDCRTFLTIMGLK 810
>33397
          Length = 1723

 Score = 26.2 bits (56), Expect = 5.2,   Method: Compositional matrix adjust.
 Identities = 18/52 (34%), Positives = 30/52 (57%), Gaps = 1/52 (1%)
 Frame = +3

Query: 92  VFDKDG-NGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEF 142
           +F K G +G IS ++   ++T L     + E+    R  DI+GDG+++ EEF
Sbjct: 111 IFYKLGEHGLISFSDYIFLLTVLSTPPRNFEI--AFRMFDINGDGELDLEEF 260
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|23956214|ref|NP_076092.1| splicing factor
proline/glutamine rich (polypyrimidine tract binding protein
associated) [Mus musculus]
         (699 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

08958                                                                 271   5e-73
19868                                                                  52   7e-07
17775                                                                  48   2e-05
02347                                                                  47   3e-05
00029                                                                  47   3e-05
28652                                                                  45   8e-05
31310                                                                  44   2e-04
20169                                                                  44   3e-04
13822                                                                  42   0.001
02415                                                                  41   0.001
30672                                                                  41   0.001
16427                                                                  40   0.004
10194                                                                  39   0.005
02064                                                                  38   0.012
12350                                                                  38   0.017
00302                                                                  37   0.020
03000                                                                  37   0.021
03406                                                                  37   0.026
17681                                                                  37   0.028
03200                                                                  36   0.054
02809                                                                  36   0.060
31618                                                                  36   0.067
24983                                                                  35   0.074
08670                                                                  35   0.076
06580                                                                  35   0.12 
02882                                                                  35   0.15 
23395                                                                  35   0.15 
01278                                                                  34   0.20 
11126                                                                  33   0.26 
05987                                                                  33   0.47 
00556                                                                  33   0.55 
02343                                                                  33   0.56 
23655                                                                  32   0.58 
05273                                                                  32   0.59 
33516                                                                  32   0.65 
19556                                                                  32   0.91 
15503                                                                  32   1.2  
32386                                                                  32   1.2  
33504                                                                  31   1.7  
25746                                                                  30   2.4  
23322                                                                  30   2.5  
08816                                                                  30   2.7  
28455                                                                  30   4.6  
>08958
          Length = 680

 Score =  271 bits (694), Expect = 5e-73,   Method: Compositional matrix adjust.
 Identities = 127/210 (60%), Positives = 159/210 (75%)
 Frame = +2

Query: 283 KTYTQRCRLFVGNLPADITEDEFKRLFAKYGEPGEVFINKGKGFGFIKLESRALAEIAKA 342
           K +T RCRLFVGNL  D++ED+FK+LF+ +GE  E ++N G+GFGFI+L+ R  AE AKA
Sbjct: 50  KKFTGRCRLFVGNLTPDVSEDDFKKLFSPFGEVSEAYVNSGRGFGFIRLDYRHNAEAAKA 229

Query: 343 ELDDTPMRGRQLRVRFATHAAALSVRNLSPYVSNELLEEAFSQFGPIERAVVIVDDRGRS 402
            LD    +GR LRVR+ATH AAL V+NL PYVSNELLE+AF+QFG +ERA+VIVD+RGRS
Sbjct: 230 ALDGLQRKGRSLRVRYATHGAALKVKNLHPYVSNELLEQAFTQFGDLERAIVIVDERGRS 409

Query: 403 TGKGIVEFASKPAARKAFERCSEGVFLLTTTPRPVIVEPLEQLDDEDGLPEKLAQKNPMY 462
           TG+G+VEF  KP A++A  R +EGVFL    P+P+ VEPLE  D+EDGLPEK   KN  Y
Sbjct: 410 TGEGVVEFVRKPGAQQALRRINEGVFLFGADPKPIEVEPLEHKDEEDGLPEKFLGKNEQY 589

Query: 463 QKERETPPRFAQHGTFEYEYSQRWKSLDEM 492
            KERE  P FA  G+FE+E+  RWK L E+
Sbjct: 590 LKEREKDPHFAPKGSFEFEFGMRWKQLAEL 679
>19868
          Length = 434

 Score = 52.4 bits (124), Expect = 7e-07,   Method: Compositional matrix adjust.
 Identities = 41/144 (28%), Positives = 67/144 (46%), Gaps = 16/144 (11%)
 Frame = +2

Query: 290 RLFVGNLPADITEDEFKRLFAKYGEPGEVFINK------GKGFGFI---------KLESR 334
           ++FVG L    + +  +  F K+GE  EV + K       +GFGFI         K+ ++
Sbjct: 2   KMFVGGLSWQTSPESLRDYFNKFGEITEVMVMKDPTTRRSRGFGFITFGDPASVDKVLAQ 181

Query: 335 ALAEIAKAELDDTPMRGRQLRVRFATHAAALSVRNLSPYVSNELLEEAFSQFGPIERAVV 394
           A  E+   ++D      R+   R  T    + V  LS   + E ++  F QFGPIE A++
Sbjct: 182 ATHELDGKKIDPKVAFPRRAHPRMVTRTKKIFVGGLSAPTTLEDVKNYFEQFGPIEDAML 361

Query: 395 IVDDR-GRSTGKGIVEFASKPAAR 417
           + D +  R  G G V  + +  +R
Sbjct: 362 MFDKQTNRHRGFGFVTISKRRHSR 433
>17775
          Length = 1282

 Score = 47.8 bits (112), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 42/145 (28%), Positives = 61/145 (42%), Gaps = 24/145 (16%)
 Frame = -2

Query: 322 KGKGFGFIKLESRALAEIAKAELDDTPMRGR---------------QLRVRFAT------ 360
           K +GFGF+  E    AE A  E++ T + GR               +L+ RF        
Sbjct: 537 KSRGFGFVSFEEPEGAEKAVDEINGTEVSGRIIYCGRAQKRAERQAELKERFEKIKLERI 358

Query: 361 ---HAAALSVRNLSPYVSNELLEEAFSQFGPIERAVVIVDDRGRSTGKGIVEFASKPAAR 417
                  L V+NL   + +E L + FS FG I  A ++ +  GRS G G V F+S   A 
Sbjct: 357 NRYQGVNLYVKNLDDSIDDERLRKEFSNFGTITSAKIMTEG-GRSKGFGFVCFSSPEEAT 181

Query: 418 KAFERCSEGVFLLTTTPRPVIVEPL 442
           KA         +     R ++ +PL
Sbjct: 180 KA---------VTEMNGRIIVAKPL 133

 Score = 28.9 bits (63), Expect = 7.2,   Method: Compositional matrix adjust.
 Identities = 21/77 (27%), Positives = 34/77 (44%), Gaps = 4/77 (5%)
 Frame = -2

Query: 287 QRCRLFVGNLPADITEDEFKRLFAKYGEPGEVFI----NKGKGFGFIKLESRALAEIAKA 342
           Q   L+V NL   I ++  ++ F+ +G      I     + KGFGF+   S   A  A  
Sbjct: 348 QGVNLYVKNLDDSIDDERLRKEFSNFGTITSAKIMTEGGRSKGFGFVCFSSPEEATKAVT 169

Query: 343 ELDDTPMRGRQLRVRFA 359
           E++   +  + L V  A
Sbjct: 168 EMNGRIIVAKPLYVALA 118
>02347
          Length = 928

 Score = 47.0 bits (110), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 25/72 (34%), Positives = 41/72 (56%), Gaps = 1/72 (1%)
 Frame = -3

Query: 290 RLFVGNLPADITEDEFKRLFAKYGEPGEVFINKG-KGFGFIKLESRALAEIAKAELDDTP 348
           +++VG+LP D +E E +R F  YG    V++ +   GF F++ E    A+ A   LD T 
Sbjct: 743 KIYVGDLPPDASEKEVERAFNYYGHLRNVWVARNPPGFAFVEFEDTRDADDAVRALDGTV 564

Query: 349 MRGRQLRVRFAT 360
           + G ++RV  +T
Sbjct: 563 VCGNRVRVEHST 528
>00029
          Length = 2204

 Score = 47.0 bits (110), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 25/79 (31%), Positives = 42/79 (53%)
 Frame = -3

Query: 285  YTQRCRLFVGNLPADITEDEFKRLFAKYGEPGEVFINKGKGFGFIKLESRALAEIAKAEL 344
            Y    ++F+GNL  D   +E + LF KYG   E  +   K FGF+ +  +  A+ A + L
Sbjct: 2148 YNMTIKIFIGNLGDDTDPEELRALFEKYGSVAECDVL--KNFGFVHMVKKGEADDAISNL 1975

Query: 345  DDTPMRGRQLRVRFATHAA 363
            +   + G+++RV  +T A 
Sbjct: 1974 NGYNIGGQRMRVELSTGAG 1918
>28652
          Length = 918

 Score = 45.4 bits (106), Expect = 8e-05,   Method: Compositional matrix adjust.
 Identities = 42/154 (27%), Positives = 64/154 (41%), Gaps = 22/154 (14%)
 Frame = -2

Query: 290 RLFVGNLPADITEDEFKRLFAKYGEP-GEVFIN--------KGKGFGFIKLESRALAEIA 340
           RLFVGN+P   T++E  + F K+ E   +V +         K +GF F++ ++   A  A
Sbjct: 485 RLFVGNIPKSKTKEEILKEFEKHSEGLMDVIVYGSADNPKLKNRGFAFLEYDTHKNASAA 306

Query: 341 KAELDDTPMRGRQLRVRF-------------ATHAAALSVRNLSPYVSNELLEEAFSQFG 387
           K        R  Q  V                +    L VRNL+  V+ + L+E F  +G
Sbjct: 305 KRRFTTGRFRVWQCDVIVDWADLQEEPNEETMSKVKVLYVRNLTGDVTEDDLKEKFGAYG 126

Query: 388 PIERAVVIVDDRGRSTGKGIVEFASKPAARKAFE 421
            +ER   I D        G V +  +  A KA +
Sbjct: 125 KVERVKKIKD-------YGFVHYEDREDALKALD 45

 Score = 40.8 bits (94), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 28/72 (38%), Positives = 37/72 (51%)
 Frame = -2

Query: 275 SLLRRPGEKTYTQRCRLFVGNLPADITEDEFKRLFAKYGEPGEVFINKGKGFGFIKLESR 334
            L   P E+T ++   L+V NL  D+TED+ K  F  YG+   V   K K +GF+  E R
Sbjct: 242 DLQEEPNEETMSKVKVLYVRNLTGDVTEDDLKEKFGAYGKVERV--KKIKDYGFVHYEDR 69

Query: 335 ALAEIAKAELDD 346
              E A   LDD
Sbjct: 68  ---EDALKALDD 42
>31310
          Length = 469

 Score = 44.3 bits (103), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 23/74 (31%), Positives = 40/74 (54%), Gaps = 6/74 (8%)
 Frame = -3

Query: 289 CRLFVGNLPADITEDEFKRLFAKYGEPGEV------FINKGKGFGFIKLESRALAEIAKA 342
           CR++VG++  +I ED  K+ F  +G    V        NK KGF FI+ +    A++A  
Sbjct: 323 CRIYVGSINFEIREDTIKQAFLPFGPIKSVNLSWDPITNKHKGFSFIEYDVPEAAQLALE 144

Query: 343 ELDDTPMRGRQLRV 356
           +++   + GR ++V
Sbjct: 143 QMNGVMIGGRNIKV 102
>20169
          Length = 1364

 Score = 43.5 bits (101), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 24/76 (31%), Positives = 39/76 (51%), Gaps = 1/76 (1%)
 Frame = -1

Query: 282  EKTYTQRCRLFVGNLPADITEDEFKRLFAKYGEPGEVFI-NKGKGFGFIKLESRALAEIA 340
             + ++  C+++VG L     + E +  FAKYG    V++  +  GF F++ E    AE A
Sbjct: 1091 HRDFSLDCKVYVGELGHGCAKQELEDKFAKYGPLKNVWVARRPAGFAFVEFEDNRDAEDA 912

Query: 341  KAELDDTPMRGRQLRV 356
               LD   + GR+ RV
Sbjct: 911  VQALDGARINGRRARV 864
>13822
          Length = 963

 Score = 42.0 bits (97), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 29/91 (31%), Positives = 49/91 (53%), Gaps = 4/91 (4%)
 Frame = -1

Query: 290 RLFVGNLPADITEDEFKRLFAKYGEPGEV---FINKG-KGFGFIKLESRALAEIAKAELD 345
           RL V N+P    E + ++L   +G   +V   F  +G KGFGF+     A AE A+ +++
Sbjct: 339 RLHVSNIPFRFREADLRQLLGPFGTILDVEIIFNERGSKGFGFVTFAHSAEAERARDKMN 160

Query: 346 DTPMRGRQLRVRFATHAAALSVRNLSPYVSN 376
            T + GR++ V  AT A  ++ +  +P + N
Sbjct: 159 GTVVEGRKIEVNNAT-ARVMTKKVAAPSIPN 70
>02415
          Length = 2763

 Score = 41.2 bits (95), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 28/94 (29%), Positives = 46/94 (48%), Gaps = 7/94 (7%)
 Frame = -1

Query: 273  NLSLLRRPGEKTYTQRCRLFVGNLPADITEDEFKRLFAKYGEPGEVFI------NKGKGF 326
            N +L+    + TYT   ++FVG LP   T+   +  F K+G+  E  +       K +G+
Sbjct: 1965 NPALITGQKDTTYT---KIFVGGLPYHTTDHSLREYFDKFGDIDEAVVITDRQTGKSRGY 1795

Query: 327  GFIKLESRALAEIAKAELDDTP-MRGRQLRVRFA 359
            GF+ +  R  A+  +A  D  P + GR+  V  A
Sbjct: 1794 GFVTMADRTGAD--RACKDPNPIIDGRKANVNLA 1699

 Score = 36.2 bits (82), Expect = 0.045,   Method: Compositional matrix adjust.
 Identities = 25/73 (34%), Positives = 35/73 (47%), Gaps = 1/73 (1%)
 Frame = -1

Query: 367  VRNLSPYVSNELLEEAFSQFGPIERAVVIVD-DRGRSTGKGIVEFASKPAARKAFERCSE 425
            V  L  + ++  L E F +FG I+ AVVI D   G+S G G V  A +  A +A   C +
Sbjct: 1914 VGGLPYHTTDHSLREYFDKFGDIDEAVVITDRQTGKSRGYGFVTMADRTGADRA---CKD 1744

Query: 426  GVFLLTTTPRPVI 438
                    P P+I
Sbjct: 1743 --------PNPII 1729
>30672
          Length = 877

 Score = 41.2 bits (95), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 22/79 (27%), Positives = 40/79 (50%), Gaps = 5/79 (6%)
 Frame = +3

Query: 287 QRCRLFVGNLPADITEDEFKRLFAKYGEPGEVFI-----NKGKGFGFIKLESRALAEIAK 341
           +RCRL + NL     E + +  F K+G   EV I     ++ +GF F++      A+ A 
Sbjct: 399 KRCRLIIRNLAFKCKEADIRSHFGKFGTISEVTIPLKQGDRSRGFAFVQFTEVKAAQKAI 578

Query: 342 AELDDTPMRGRQLRVRFAT 360
           ++++ T +  R + V +A 
Sbjct: 579 SDMNGTAIMDRPVAVDWAV 635

 Score = 38.9 bits (89), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 25/60 (41%), Positives = 32/60 (53%), Gaps = 1/60 (1%)
 Frame = +3

Query: 361 HAAALSVRNLSPYVSNELLEEAFSQFGPIERAVVIVDDR-GRSTGKGIVEFASKPAARKA 419
            +  L VRNL    SNE L EAF Q GP++ A V+     G+  G G V+F+    A KA
Sbjct: 6   QSKTLFVRNLPFETSNEKLLEAFEQVGPLKTAFVVAGKEPGKCRGFGYVQFSMLEDAIKA 185

 Score = 32.7 bits (73), Expect = 0.48,   Method: Compositional matrix adjust.
 Identities = 22/75 (29%), Positives = 36/75 (48%), Gaps = 6/75 (8%)
 Frame = +3

Query: 291 LFVGNLPADITEDEFKRLFAKYGEPGEVFINKGK------GFGFIKLESRALAEIAKAEL 344
           LFV NLP + + ++    F + G     F+  GK      GFG+++     L +  KA+ 
Sbjct: 18  LFVRNLPFETSNEKLLEAFEQVGPLKTAFVVAGKEPGKCRGFGYVQFS--MLEDAIKAKD 191

Query: 345 DDTPMRGRQLRVRFA 359
             T   GR++ + FA
Sbjct: 192 TVTHCSGRKISLSFA 236

 Score = 30.8 bits (68), Expect = 1.8,   Method: Compositional matrix adjust.
 Identities = 21/76 (27%), Positives = 32/76 (42%)
 Frame = +3

Query: 365 LSVRNLSPYVSNELLEEAFSQFGPIERAVVIVDDRGRSTGKGIVEFASKPAARKAFERCS 424
           L +RNL+       +   F +FG I    + +    RS G   V+F    AA+KA    +
Sbjct: 411 LIIRNLAFKCKEADIRSHFGKFGTISEVTIPLKQGDRSRGFAFVQFTEVKAAQKAISDMN 590

Query: 425 EGVFLLTTTPRPVIVE 440
               +     RPV V+
Sbjct: 591 GTAIM----DRPVAVD 626
>16427
          Length = 1313

 Score = 40.0 bits (92), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 26/80 (32%), Positives = 39/80 (48%), Gaps = 6/80 (7%)
 Frame = +1

Query: 290 RLFVGNLPADITEDEFKRLFAKYGEPGEVFINKGK------GFGFIKLESRALAEIAKAE 343
           +LFVG L  +I E   +R F+K+G   E  + + K      GFGF+  E+   AE A   
Sbjct: 139 KLFVGGLAEEIDEKVLEREFSKFGRITESMVIRDKVRQVSRGFGFVTYENPMDAEEAVKH 318

Query: 344 LDDTPMRGRQLRVRFATHAA 363
           +D   + G++L V  A    
Sbjct: 319 MDGKEILGKKLHVEDAVRGG 378
>10194
          Length = 1278

 Score = 39.3 bits (90), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 24/79 (30%), Positives = 41/79 (51%), Gaps = 6/79 (7%)
 Frame = -3

Query: 291 LFVGNLPADITEDEFKRLFAKYGEPGEVFI------NKGKGFGFIKLESRALAEIAKAEL 344
           +FVGNLP DI E+  +  F   G+   + +      N GKG  +I  +S     +A  +L
Sbjct: 400 VFVGNLPFDIEEESVRSHFEDCGDVENIRVVRDRKTNLGKGICYILFKSADSVSLA-LKL 224

Query: 345 DDTPMRGRQLRVRFATHAA 363
           +++ +  RQ+RV+    A+
Sbjct: 223 NNSELEKRQIRVQRCKDAS 167
>02064
          Length = 1195

 Score = 38.1 bits (87), Expect = 0.012,   Method: Compositional matrix adjust.
 Identities = 19/58 (32%), Positives = 36/58 (62%)
 Frame = +1

Query: 363 AALSVRNLSPYVSNELLEEAFSQFGPIERAVVIVDDRGRSTGKGIVEFASKPAARKAF 420
             + V+NL   ++ + L E F + G ++ + + +D +GRSTG+G+V FA++  A +A 
Sbjct: 79  CTVQVKNLPYAITWQDLRERFQEIGVVKYSEITMD-KGRSTGQGLVRFATEDDAVRAI 249
>12350
          Length = 975

 Score = 37.7 bits (86), Expect = 0.017,   Method: Compositional matrix adjust.
 Identities = 24/88 (27%), Positives = 44/88 (50%), Gaps = 4/88 (4%)
 Frame = -2

Query: 277 LRRPGEKTYTQRC---RLFVGNLPADITEDEFKRLFAKYGEPGEVFINK-GKGFGFIKLE 332
           +R P  K   Q+    ++FVG    D+T D+ ++ F+K+GE  +VFI +  + F F+   
Sbjct: 407 VRIPNSKEGAQQLMNRKIFVGRCTDDMTADDLRQFFSKFGEVVDVFIPRPFRAFAFVSFA 228

Query: 333 SRALAEIAKAELDDTPMRGRQLRVRFAT 360
              +A+    E  D  ++G  + +  A 
Sbjct: 227 DPEVAQSLYGE--DHIIKGASVHISGAA 150
>00302
          Length = 927

 Score = 37.4 bits (85), Expect = 0.020,   Method: Compositional matrix adjust.
 Identities = 22/62 (35%), Positives = 30/62 (48%), Gaps = 1/62 (1%)
 Frame = -1

Query: 364 ALSVRNLSPYVSNELLEEAFSQFGPIERAVVIVDDR-GRSTGKGIVEFASKPAARKAFER 422
            L +  LS Y     L E F ++G I    V+ D + GRS G   V F S   A +A +R
Sbjct: 462 CLGIFGLSLYTQERGLREVFGRYGHISEVQVVYDRQTGRSRGFAFVYFKSSEDAHEAKDR 283

Query: 423 CS 424
           C+
Sbjct: 282 CN 277
>03000
          Length = 778

 Score = 37.4 bits (85), Expect = 0.021,   Method: Compositional matrix adjust.
 Identities = 33/152 (21%), Positives = 64/152 (42%), Gaps = 22/152 (14%)
 Frame = +3

Query: 290 RLFVGNLPADITEDEFKRLFAKYGEPGEVFI------NKGKGFGFIKLESRALAEIAKAE 343
           +LF+G L  +  ED  +  F  +GE  +  +       + +GFGFI  +     + A+A 
Sbjct: 90  KLFIGGLSYETDEDSLRSHFETWGEIVDCIVMRDSNSKRSRGFGFITYKDAESIDQAQA- 266

Query: 344 LDDTP--MRGRQLRVRFAT------------HAAALSVRNLSPYVSNELLEEAFSQFGPI 389
             + P  + GR++  + A                 + V  +    + +++ + F++FG I
Sbjct: 267 --NRPHKIDGREVDTKRAMPREESGRSEVQQSVKKMFVGGVKEDTTEDMIRDTFNEFGEI 440

Query: 390 ERAVVIVDDRGRSTGKG--IVEFASKPAARKA 419
              V ++ D+G    +G   V F    +  KA
Sbjct: 441 T-GVDLIQDKGTGKNRGFCFVTFGDHDSVDKA 533
>03406
          Length = 1292

 Score = 37.0 bits (84), Expect = 0.026,   Method: Compositional matrix adjust.
 Identities = 40/164 (24%), Positives = 70/164 (42%), Gaps = 17/164 (10%)
 Frame = +3

Query: 290 RLFVGNLPADITEDEFKRLFAKYGEPGEVFI------NKGKGFGFIKLESRALAEIAKAE 343
           ++FVG L  +      +  F K+GE     +       K +GFGF+  +  A  + A  +
Sbjct: 243 KIFVGGLSWETXSKHLREYFEKFGEVTSCTLKTDLDSGKSRGFGFVVFKEAATVD-AVVK 419

Query: 344 LDDTPMRGRQLRVRFATHAAALS---VRNLSPYVSNELLEEAFSQFGPIERAVVIVD--- 397
             +  ++GR++  + A     +    V  L P V  E +E  F++FG +    +  D   
Sbjct: 420 NKEHKLQGRKIDPKPANPRKGMRKIFVGKLDPGVPQEDVESYFAKFGKVVNVELPYDKVK 599

Query: 398 DRGRSTGKGIVEFASKPAARKAFERCS-----EGVFLLTTTPRP 436
           D+ R+     VEF +    +K  E+ S     + V +   TP P
Sbjct: 600 DQRRAF--CFVEFDNDKTVKKVLEQTSHKIGGQEVDVKKATPNP 725
>17681
          Length = 964

 Score = 37.0 bits (84), Expect = 0.028,   Method: Compositional matrix adjust.
 Identities = 21/77 (27%), Positives = 36/77 (46%), Gaps = 6/77 (7%)
 Frame = +2

Query: 290 RLFVGNLPADITEDEFKRLFAKYGEPGEVFI------NKGKGFGFIKLESRALAEIAKAE 343
            +FVG+L  +I  +  +  FA +GE     I       K KG+ F+    +A AE A   
Sbjct: 35  HIFVGDLSPEIETETLREAFAPFGEISNCRIVRDPQTMKSKGYAFVSFVKKAEAENAIQA 214

Query: 344 LDDTPMRGRQLRVRFAT 360
           ++   +  R +R  ++T
Sbjct: 215 MNGQWIGSRSIRTNWST 265

 Score = 34.7 bits (78), Expect = 0.13,   Method: Compositional matrix adjust.
 Identities = 21/84 (25%), Positives = 37/84 (44%), Gaps = 5/84 (5%)
 Frame = +2

Query: 278 RRPGEKTYTQ----RCRLFVGNLPADITEDEF-KRLFAKYGEPGEVFINKGKGFGFIKLE 332
           R   E+ Y Q       ++ G  P ++  DE   + F ++G   +V + K KGF FIK  
Sbjct: 377 RHTFEEVYNQSSPTNTTVYCGGFPPNVISDELMHKHFMQFGPIQDVRVFKDKGFAFIKFV 556

Query: 333 SRALAEIAKAELDDTPMRGRQLRV 356
           ++  A  A      + + G  ++ 
Sbjct: 557 TKEAAARAIEHTHISEVHGNHVKC 628

 Score = 34.7 bits (78), Expect = 0.14,   Method: Compositional matrix adjust.
 Identities = 20/58 (34%), Positives = 29/58 (50%), Gaps = 1/58 (1%)
 Frame = +2

Query: 365 LSVRNLSPYVSNELLEEAFSQFGPIERAVVIVDDRG-RSTGKGIVEFASKPAARKAFE 421
           + V +LSP +  E L EAF+ FG I    ++ D +  +S G   V F  K  A  A +
Sbjct: 38  IFVGDLSPEIETETLREAFAPFGEISNCRIVRDPQTMKSKGYAFVSFVKKAEAENAIQ 211

 Score = 34.3 bits (77), Expect = 0.15,   Method: Compositional matrix adjust.
 Identities = 18/49 (36%), Positives = 27/49 (55%)
 Frame = +2

Query: 374 VSNELLEEAFSQFGPIERAVVIVDDRGRSTGKGIVEFASKPAARKAFER 422
           +S+EL+ + F QFGPI+   V  D      G   ++F +K AA +A E 
Sbjct: 458 ISDELMHKHFMQFGPIQDVRVFKDK-----GFAFIKFVTKEAAARAIEH 589
>03200
          Length = 657

 Score = 35.8 bits (81), Expect = 0.054,   Method: Compositional matrix adjust.
 Identities = 26/102 (25%), Positives = 45/102 (44%), Gaps = 3/102 (2%)
 Frame = -1

Query: 300 ITEDEFKRLFAKYGEPGEVFINKGKGFGFIKLESRALAEIAKAELDDTPMRGRQLRVRFA 359
           +TED  K  F+ +G    + I + +  GF+  E    A+ A A ++ + +   QL+V  A
Sbjct: 459 VTEDILKSAFSNFGNIVNINIERERNNGFVTFEKMESADQAIANMNGSMISNVQLKVMMA 280

Query: 360 THAAALSVRNLSPYVSNELLEEAFSQFGPI---ERAVVIVDD 398
               +    N     +   +  + SQ GP    +R +V  DD
Sbjct: 279 RRQPSFDSVNDPSTTTWSSIAASHSQKGPSRKEDRDMVQYDD 154
>02809
          Length = 1475

 Score = 35.8 bits (81), Expect = 0.060,   Method: Compositional matrix adjust.
 Identities = 20/68 (29%), Positives = 34/68 (50%), Gaps = 1/68 (1%)
 Frame = -1

Query: 282  EKTYTQRCRLFVGNLPADITEDEFKRLFAKYGEPGEVFINKG-KGFGFIKLESRALAEIA 340
             + ++  C+++VG L     + E +  FAKYG    V++ +   GF F++ E    AE A
Sbjct: 1355 HRDFSLDCKVYVGELGHGCAKQELEDKFAKYGPLKNVWVARRPAGFAFVEFEDNRDAEDA 1176

Query: 341  KAELDDTP 348
               LD + 
Sbjct: 1175 VQALDGSA 1152
>31618
          Length = 716

 Score = 35.8 bits (81), Expect = 0.067,   Method: Compositional matrix adjust.
 Identities = 20/61 (32%), Positives = 32/61 (52%), Gaps = 7/61 (11%)
 Frame = +1

Query: 290 RLFVGNLPADITEDEFKRLFAKYGEPGEVFI------NKGKGFGFIKL-ESRALAEIAKA 342
           +LFVG L  + TE E +  F KYGE   + +       + +GF FI    + A+ +++ A
Sbjct: 295 KLFVGGLSWETTEKELRDHFGKYGEIESINVKTDPQTGRSRGFAFIVFTNTEAIDQVSAA 474

Query: 343 E 343
           E
Sbjct: 475 E 477
>24983
          Length = 433

 Score = 35.4 bits (80), Expect = 0.074,   Method: Composition-based stats.
 Identities = 21/50 (42%), Positives = 29/50 (58%), Gaps = 2/50 (4%)
 Frame = -2

Query: 372 PY-VSNELLEEAFSQFGPIERAVVIVDDR-GRSTGKGIVEFASKPAARKA 419
           PY  ++  L E F +FG I+ AVVI D + G+S G G V  A +  A +A
Sbjct: 291 PYHTTDHSLREYFDKFGDIDEAVVITDRQTGKSRGYGFVTMADRTGADRA 142
>08670
          Length = 1307

 Score = 35.4 bits (80), Expect = 0.076,   Method: Compositional matrix adjust.
 Identities = 21/68 (30%), Positives = 33/68 (48%)
 Frame = +2

Query: 291  LFVGNLPADITEDEFKRLFAKYGEPGEVFINKGKGFGFIKLESRALAEIAKAELDDTPMR 350
            L+VGN+   +TE    ++FAK+G    V +   K   FI  + +  A  A   L +    
Sbjct: 959  LWVGNVLPQVTEKRLTQMFAKHGPVASVRMLPEKYCAFINYKLKESAGRAMQYLQNQECE 1138

Query: 351  GRQLRVRF 358
            G+ L +RF
Sbjct: 1139 GQHLLIRF 1162
>06580
          Length = 1597

 Score = 34.7 bits (78), Expect = 0.12,   Method: Compositional matrix adjust.
 Identities = 26/92 (28%), Positives = 40/92 (43%), Gaps = 6/92 (6%)
 Frame = +1

Query: 274 LSLLRRPGEK----TYTQRCRLFVGNLPADITEDEFKRLFAKYGEP-GEVFINKGKGFGF 328
           L   +RPG K     +     L + N+P  ITE++ +  F  YG   G  F  K +    
Sbjct: 121 LHRFKRPGSKNCQNIFPPSAVLHLSNIPPSITEEQLQSWFTDYGTVRGFKFFQKDRKMAL 300

Query: 329 IKLESRALAEIAKAELDDTPM-RGRQLRVRFA 359
           I+L S   A +A   + +  +     LRV F+
Sbjct: 301 IQLNSVDEAILALIGMHNMQLGENSHLRVSFS 396
>02882
          Length = 2876

 Score = 34.7 bits (78), Expect = 0.15,   Method: Compositional matrix adjust.
 Identities = 24/92 (26%), Positives = 42/92 (45%), Gaps = 6/92 (6%)
 Frame = -1

Query: 274  LSLLRRPGEKT----YTQRCRLFVGNLPADITEDEFKRLFAKYGE-PGEVFINKGKGFGF 328
            L   +RPG K     +     L + N+P  +TE++ +  FA YG   G  F  K +    
Sbjct: 2756 LHRFKRPGSKNCQNIFPPSAVLHLSNIPPSVTEEQIQNWFADYGTVKGFKFFQKDRRMAL 2577

Query: 329  IKLESRALAEIAKAELDDTPM-RGRQLRVRFA 359
            I++ +   A ++   + +T +     LRV F+
Sbjct: 2576 IEMNNADEAVLSLIGMHNTQLGENSHLRVSFS 2481
>23395
          Length = 1060

 Score = 34.7 bits (78), Expect = 0.15,   Method: Compositional matrix adjust.
 Identities = 25/89 (28%), Positives = 39/89 (43%), Gaps = 6/89 (6%)
 Frame = -1

Query: 277 LRRPGEK----TYTQRCRLFVGNLPADITEDEFKRLFAKYGEP-GEVFINKGKGFGFIKL 331
            +RPG K     +     L + N+P  ITE++ +  F  YG   G  F  K +    I+L
Sbjct: 931 FKRPGSKNCQNIFPPSAVLHLSNIPPSITEEQLQSWFTDYGTVRGFKFFQKDRKMALIQL 752

Query: 332 ESRALAEIAKAELDDTPM-RGRQLRVRFA 359
            S   A +A   + +  +     LRV F+
Sbjct: 751 NSVDEAILALIGMHNMQLGENSHLRVSFS 665
>01278
          Length = 1082

 Score = 33.9 bits (76), Expect = 0.20,   Method: Compositional matrix adjust.
 Identities = 23/72 (31%), Positives = 32/72 (44%), Gaps = 1/72 (1%)
 Frame = +2

Query: 350 RGRQLRVRFATHAAALSVRNLSPYVSNELLEEAFSQFGPIERAVVIVDD-RGRSTGKGIV 408
           RG  +  +    AA + V NLS       L+E F  FGPI R  +  D   G+S G   +
Sbjct: 596 RGESMANQRKDEAATIRVTNLSEDTRESDLQELFRPFGPISRIYLAKDKVTGQSKGFAFI 775

Query: 409 EFASKPAARKAF 420
            F  +  A +A 
Sbjct: 776 NFHRREDASRAI 811
>11126
          Length = 1061

 Score = 33.5 bits (75), Expect = 0.26,   Method: Compositional matrix adjust.
 Identities = 20/72 (27%), Positives = 33/72 (45%), Gaps = 6/72 (8%)
 Frame = -3

Query: 291 LFVGNLPADITEDEFKRLFAKYGEPGEVFI------NKGKGFGFIKLESRALAEIAKAEL 344
           ++VGN+    T +E ++ F   G    V I         KGF +++   +     AK   
Sbjct: 624 VYVGNVDYGATAEELEQHFHGCGSVNRVTILCDKYSGHPKGFAYVEFADKDSVVTAKCTG 445

Query: 345 DDTPMRGRQLRV 356
            D+  RGRQ++V
Sbjct: 444 MDSLFRGRQIKV 409
>05987
          Length = 1726

 Score = 32.7 bits (73), Expect = 0.47,   Method: Compositional matrix adjust.
 Identities = 22/84 (26%), Positives = 36/84 (42%), Gaps = 7/84 (8%)
 Frame = -2

Query: 288  RCRLFVGNLPADITEDEFKRLFAKYGEPGEVFINKGK-------GFGFIKLESRALAEIA 340
            +C LFV NLP  ++  + K L     E       + K       GF +++  S ALA+  
Sbjct: 1173 KCTLFVKNLPPTVSVTDIKSLSKDIKEVRLRIAVRAKQRQKKKMGFAYVEFASEALADKN 994

Query: 341  KAELDDTPMRGRQLRVRFATHAAA 364
              +L  T ++   L V +    +A
Sbjct: 993  YKQLQGTKLKDWDLVVDYVGQKSA 922
>00556
          Length = 2189

 Score = 32.7 bits (73), Expect = 0.55,   Method: Compositional matrix adjust.
 Identities = 28/90 (31%), Positives = 39/90 (43%), Gaps = 12/90 (13%)
 Frame = +3

Query: 280 PGEKTYTQRCRLFVGNLPADITEDEFKRLFAKY----------GEPG-EVFINKGKGFGF 328
           PG     Q  RL+VGN+P  +TE+     F             G+P   V IN  K F F
Sbjct: 402 PGSAMSRQARRLYVGNIPFGVTEESMMDFFNHQMKITGLAQAEGDPVIAVHINLDKNFAF 581

Query: 329 IKLESRALAEIAKA-ELDDTPMRGRQLRVR 357
             LE R++ E  +A   D      + L++R
Sbjct: 582 --LELRSVDETTQALAFDGIAYETQPLKIR 665

 Score = 32.3 bits (72), Expect = 0.59,   Method: Compositional matrix adjust.
 Identities = 22/81 (27%), Positives = 41/81 (50%), Gaps = 7/81 (8%)
 Frame = +3

Query: 290 RLFVGNLPADITEDEFKRLFAKYGEPGEVF-------INKGKGFGFIKLESRALAEIAKA 342
           ++F+G LP+ ++ED+ K L   +G P + F           KGF F +    ++ + A A
Sbjct: 762 KIFMGGLPSYLSEDQMKELLLSFG-PLKSFNLVRDNATGLSKGFAFCEYLDPSVTDQACA 938

Query: 343 ELDDTPMRGRQLRVRFATHAA 363
            L+   +  ++L V+ A+  A
Sbjct: 939 GLNGMQLGDKKLIVQRASIGA 1001
>02343
          Length = 1715

 Score = 32.7 bits (73), Expect = 0.56,   Method: Compositional matrix adjust.
 Identities = 18/58 (31%), Positives = 28/58 (48%), Gaps = 1/58 (1%)
 Frame = -2

Query: 365  LSVRNLSPYVSNELLEEAFSQFGPIERAVVIVD-DRGRSTGKGIVEFASKPAARKAFE 421
            L +R LSP  +++ L      FG I     I+D    +  G G V+F +  AA +A +
Sbjct: 1258 LYIRGLSPNTTDKDLVNLCQHFGTITSTKAIIDQTTNKCKGYGFVDFDAPGAAERAVQ 1085

 Score = 28.9 bits (63), Expect = 8.2,   Method: Compositional matrix adjust.
 Identities = 27/132 (20%), Positives = 51/132 (38%), Gaps = 6/132 (4%)
 Frame = -2

Query: 288  RCRLFVGNLPADITEDEFKRLFAKYGEPGEV------FINKGKGFGFIKLESRALAEIAK 341
            +  L++  L  + T+ +   L   +G             NK KG+GF+  ++   AE A 
Sbjct: 1267 KTNLYIRGLSPNTTDKDLVNLCQHFGTITSTKAIIDQTTNKCKGYGFVDFDAPGAAERAV 1088

Query: 342  AELDDTPMRGRQLRVRFATHAAALSVRNLSPYVSNELLEEAFSQFGPIERAVVIVDDRGR 401
              L    ++  Q+  +       L + NL  + + + LE  F  +G +    ++    G 
Sbjct: 1087 QALQAQGIQA-QMAKQQEQDPTNLYIANLPLHFTEKHLEGLFKDYGTVISTRILRKPDGI 911

Query: 402  STGKGIVEFASK 413
            S   G     S+
Sbjct: 910  SRCVGFARMESR 875
>23655
          Length = 929

 Score = 32.3 bits (72), Expect = 0.58,   Method: Compositional matrix adjust.
 Identities = 20/63 (31%), Positives = 32/63 (50%), Gaps = 4/63 (6%)
 Frame = -1

Query: 283 KTYTQRCRLFVGNLPADITEDEFKRLFAKYGEPGEVFINKGKGFG----FIKLESRALAE 338
           ++ T R ++FVG +  D TED  +  F ++GE   V + + KG G    F+ L S     
Sbjct: 923 RSSTVREKMFVGGVKEDTTEDMIRDTFNEFGEITGVDLIQDKGTGKNRDFVSLPSVTTTP 744

Query: 339 IAK 341
           + K
Sbjct: 743 LTK 735
>05273
          Length = 1009

 Score = 32.3 bits (72), Expect = 0.59,   Method: Compositional matrix adjust.
 Identities = 19/48 (39%), Positives = 28/48 (58%), Gaps = 2/48 (4%)
 Frame = -1

Query: 370 LSPYVSNE-LLEEAFSQFGPIERAVVIVD-DRGRSTGKGIVEFASKPA 415
           ++P ++ +  L E F +FG I+ AVVI D   G+S G G V  A + A
Sbjct: 181 ITPIITTDHSLREYFDKFGDIDEAVVITDRQTGKSRGYGFVTMADRRA 38
>33516
          Length = 449

 Score = 32.3 bits (72), Expect = 0.65,   Method: Composition-based stats.
 Identities = 14/56 (25%), Positives = 29/56 (51%), Gaps = 6/56 (10%)
 Frame = +1

Query: 290 RLFVGNLPADITEDEFKRLFAKYGEPGEVFI------NKGKGFGFIKLESRALAEI 339
           ++FVG L  D  +D  +  F+++GE  +  +       K +GFGF+  +  +  ++
Sbjct: 157 KIFVGGLSWDTDQDSLQGYFSQFGEITDCIVMMNQQTGKSRGFGFVSFKDPSTVDV 324
>19556
          Length = 917

 Score = 32.0 bits (71), Expect = 0.91,   Method: Compositional matrix adjust.
 Identities = 21/85 (24%), Positives = 41/85 (48%), Gaps = 8/85 (9%)
 Frame = -1

Query: 287 QRCRLFVGNLPADITEDEFKRLFAKYGEPGEVFINK------GKGFGFIKL--ESRALAE 338
           QR   F+G L   +TE+E    F+++G+   V I         + F ++ L  E     +
Sbjct: 836 QRKENFIGGLVKGVTEEELMEKFSRFGQVSNVDIKTRTNGIDSRTFAYVNLTAEENGFKK 657

Query: 339 IAKAELDDTPMRGRQLRVRFATHAA 363
              A  ++T  +G QL++++A  ++
Sbjct: 656 CFTA-YNNTKWKGGQLKLQYAKESS 585
>15503
          Length = 570

 Score = 31.6 bits (70), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 22/71 (30%), Positives = 32/71 (45%), Gaps = 3/71 (4%)
 Frame = +1

Query: 291 LFVGNLPADITEDEFKRLFAKYGEPGEVFINK---GKGFGFIKLESRALAEIAKAELDDT 347
           L+V NLP  IT +E   +F KYG   ++ +      KG  F+  E    A+ A   L   
Sbjct: 154 LYVKNLPYKITAEEMYDIFGKYGAIRQIRVGNTPETKGTAFVVYEDIFDAKNACDHLSGF 333

Query: 348 PMRGRQLRVRF 358
            +  R L V +
Sbjct: 334 NVCNRYLVVLY 366
>32386
          Length = 674

 Score = 31.6 bits (70), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 14/46 (30%), Positives = 23/46 (50%), Gaps = 6/46 (13%)
 Frame = +1

Query: 290 RLFVGNLPADITEDEFKRLFAKYGEPGEVFI------NKGKGFGFI 329
           +LF+G L  +  ED  +  F  +GE  +  +       + +GFGFI
Sbjct: 304 KLFIGGLSYETDEDSLRSHFETWGEIVDCIVMRDSNSKRSRGFGFI 441
>33504
          Length = 282

 Score = 30.8 bits (68), Expect = 1.7,   Method: Composition-based stats.
 Identities = 12/30 (40%), Positives = 19/30 (63%)
 Frame = +1

Query: 285 YTQRCRLFVGNLPADITEDEFKRLFAKYGE 314
           Y     +F+G LP D+TE +   +F++YGE
Sbjct: 157 YKDSAWVFIGGLPYDLTEGDIICVFSQYGE 246
>25746
          Length = 475

 Score = 30.4 bits (67), Expect = 2.4,   Method: Composition-based stats.
 Identities = 10/23 (43%), Positives = 19/23 (82%)
 Frame = +1

Query: 291 LFVGNLPADITEDEFKRLFAKYG 313
           ++V  LP+D+T+++F+ L +KYG
Sbjct: 79  VYVSGLPSDLTDEQFQELMSKYG 147
>23322
          Length = 471

 Score = 30.4 bits (67), Expect = 2.5,   Method: Compositional matrix adjust.
 Identities = 23/77 (29%), Positives = 36/77 (46%), Gaps = 7/77 (9%)
 Frame = -2

Query: 290 RLFVGNLPADITEDEFKRLFAKYGEPGEVFI------NKGKGFGFIKLESRALAEIAKAE 343
           ++FVG +  D TED  +  F ++GE   V +       K +GF F+         + KA 
Sbjct: 407 KMFVGGVKEDTTEDMIRDTFNEFGEITGVDLIQDKGTGKNRGFCFVTFGDH--DSVDKAV 234

Query: 344 LDD-TPMRGRQLRVRFA 359
           L     + GRQ+ V+ A
Sbjct: 233 LKKRHDLNGRQVEVKKA 183
>08816
          Length = 566

 Score = 30.4 bits (67), Expect = 2.7,   Method: Composition-based stats.
 Identities = 21/73 (28%), Positives = 37/73 (50%), Gaps = 4/73 (5%)
 Frame = +1

Query: 288 RCRLFVGNLPADITEDEFKRLFAKYGEP--GEVFINKGK--GFGFIKLESRALAEIAKAE 343
           RC + V N+P  +T  E +  F   G+    E+ +++G+  G   ++  + A A  A   
Sbjct: 46  RCTVTVRNVPFSLTWQELRERFQDIGDVKFSEILMDQGRPSGDAVVRFGTSADAMRAINL 225

Query: 344 LDDTPMRGRQLRV 356
           +D T + GR +RV
Sbjct: 226 VDGTRIDGRTVRV 264
>28455
          Length = 573

 Score = 29.6 bits (65), Expect = 4.6,   Method: Compositional matrix adjust.
 Identities = 16/67 (23%), Positives = 34/67 (50%), Gaps = 5/67 (7%)
 Frame = -1

Query: 284 TYTQRCRLFVGNLPADITEDEFKRLFAKYGEPGEVFI-----NKGKGFGFIKLESRALAE 338
           T  ++ +LFV NLP   + +  + +F ++G+  +V +        KG  +++ E+  +A 
Sbjct: 555 TSLEKNKLFVKNLPFTCSAEALETIFKEHGKVKDVRLVTYRSGASKGLAYVEFETEEMAT 376

Query: 339 IAKAELD 345
            A  + D
Sbjct: 375 QAVMKTD 355
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6680067|ref|NP_032181.1| glucose phosphate isomerase
1 [Mus musculus]
         (558 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

09208                                                                 271   5e-73
27738                                                                  32   0.58 
24075                                                                  29   5.1  
>09208
          Length = 2252

 Score =  271 bits (693), Expect = 5e-73,   Method: Compositional matrix adjust.
 Identities = 125/172 (72%), Positives = 147/172 (85%)
 Frame = +3

Query: 382 EPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQHPIRKGLHHKILLANFLAQTEALMKGKL 441
           EPGTNGQHAFYQLIHQG ++IPCDFL+PV+T +P++ GLHH+IL ANFLAQTEALM GK 
Sbjct: 3   EPGTNGQHAFYQLIHQGMRLIPCDFLLPVKTLNPVQDGLHHEILQANFLAQTEALMLGKS 182

Query: 442 PEEARKELQAAGKSPEDLEKLLPHKVFEGNRPTNSIVFTKLTPFILGALIAMYEHKIFVQ 501
            EEAR EL+ +G   +D+E +LPHKVF GNRP+NSIVF +LTPF+LG LIAMYEHKI VQ
Sbjct: 183 TEEARAELEKSGMVQKDIEHILPHKVFRGNRPSNSIVFKQLTPFMLGELIAMYEHKIHVQ 362

Query: 502 GIMWDINSFDQWGVELGKQLAKKIEPELEGSSAVTSHDSSTNGLISFIKQQR 553
           G++WDINS+DQWGVELGKQLAK I+PEL+G   V +HDSSTNGLI FIK  R
Sbjct: 363 GVIWDINSYDQWGVELGKQLAKVIQPELKGDGTVNTHDSSTNGLIDFIKTHR 518
>27738
          Length = 528

 Score = 32.3 bits (72), Expect = 0.58,   Method: Composition-based stats.
 Identities = 17/45 (37%), Positives = 22/45 (48%)
 Frame = -2

Query: 382 EPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQHPIRKGLHHKILL 426
           EPG  G    +QL H+ T + PC    P    HP R G   ++LL
Sbjct: 158 EPG--G*RQPHQLTHRPTVVAPC*RYAPAHPSHPARDGCSSRLLL 30
>24075
          Length = 1861

 Score = 28.9 bits (63), Expect = 5.1,   Method: Compositional matrix adjust.
 Identities = 13/29 (44%), Positives = 18/29 (62%)
 Frame = -1

Query: 484  PFILGALIAMYEHKIFVQGIMWDINSFDQ 512
            PFI GAL+  +  KI +  + WD + FDQ
Sbjct: 1777 PFIKGALLVEFWSKI-ITNVFWDYSKFDQ 1694
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6680690|ref|NP_031478.1| peroxiredoxin 3 [Mus
musculus]
         (257 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

09130                                                                 270   5e-73
10721                                                                 260   3e-70
09123                                                                  67   8e-12
14066                                                                  28   5.0  
>09130
          Length = 1000

 Score =  270 bits (690), Expect = 5e-73,   Method: Compositional matrix adjust.
 Identities = 128/223 (57%), Positives = 158/223 (70%)
 Frame = +1

Query: 32  PVASRRTCLTDILWSASAQGKSAFSTSSSFHTPAVTQHAPYFKGTAVVNGEFKELSLDDF 91
           P  +RRT    I WS +                 +++ AP + GTAV++GEFK++ L DF
Sbjct: 145 PQETRRTSGHSIQWSQAV----------------ISKPAPDWNGTAVIDGEFKDIKLSDF 276

Query: 92  KGKYLVLFFYPLDFTFVCPTEIVAFSDKANEFHDVNCEVVAVSVDSHFSHLAWINTPRKN 151
           +GKYLV FFYPLDFTFVCPTEIVAFSD   +F  +N EVVA SVDS F+HLAWINTPR  
Sbjct: 277 RGKYLVFFFYPLDFTFVCPTEIVAFSDNVGKFKSINTEVVACSVDSQFTHLAWINTPRNQ 456

Query: 152 GGLGHMNITLLSDITKQISRDYGVLLESAGIALRGLFIIDPNGVVKHLSVNDLPVGRSVE 211
           GGLG + I LLSDIT  I++ YGV L+  G +LRGLFIIDP G+++ +++NDLPVGRSV+
Sbjct: 457 GGLGPLKIPLLSDITHDIAKAYGVYLQDLGHSLRGLFIIDPKGILRQITMNDLPVGRSVD 636

Query: 212 ETLRLVKAFQFVETHGEVCPANWTPESPTIKPSPTASKEYFEK 254
           ETLRLV+AFQ+ + HGEVCP  W P S TI P P  SK+YF K
Sbjct: 637 ETLRLVQAFQYTDAHGEVCPVGWKPGSDTIIPDPKQSKKYFNK 765
>10721
          Length = 1542

 Score =  260 bits (665), Expect = 3e-70,   Method: Compositional matrix adjust.
 Identities = 119/192 (61%), Positives = 147/192 (76%)
 Frame = -2

Query: 65   AVTQHAPYFKGTAVVNGEFKELSLDDFKGKYLVLFFYPLDFTFVCPTEIVAFSDKANEFH 124
            A+ + AP F   AVV+G+FK + L D+KGKY+VLFFYPLDFTFVCPTEI+AFSD+  EF 
Sbjct: 1454 AIQKPAPEFSVQAVVDGDFKTVKLSDYKGKYVVLFFYPLDFTFVCPTEIIAFSDRVEEFR 1275

Query: 125  DVNCEVVAVSVDSHFSHLAWINTPRKNGGLGHMNITLLSDITKQISRDYGVLLESAGIAL 184
             + CEV+A S DS FSHLAW+NTPRK GGLG+M I LL+D T ++SR YG L E  GIA 
Sbjct: 1274 SIQCEVLAASTDSVFSHLAWVNTPRKQGGLGNMKIPLLADKTLELSRMYGCLKEDEGIAY 1095

Query: 185  RGLFIIDPNGVVKHLSVNDLPVGRSVEETLRLVKAFQFVETHGEVCPANWTPESPTIKPS 244
            R L+IID  G ++ +++NDLPVGRSV+ETLRLV+AFQF + HGEVCPA W P + TIKPS
Sbjct: 1094 RALYIIDDKGTLRQITMNDLPVGRSVDETLRLVQAFQFTDKHGEVCPAGWKPGADTIKPS 915

Query: 245  PTASKEYFEKVH 256
               SK +F K +
Sbjct: 914  VKDSKTFFSKAN 879
>09123
          Length = 1944

 Score = 67.0 bits (162), Expect = 8e-12,   Method: Compositional matrix adjust.
 Identities = 40/151 (26%), Positives = 69/151 (45%), Gaps = 9/151 (5%)
 Frame = -3

Query: 95   YLVLFFYPLDFTFVCPTEIVAFSDKANEFHDVNCEVVAVSVDSHFSHLAWINTPRKNGGL 154
            + +LF +P D+T VC TE+    +   EF    C+V A+S D   SH  W    +K  G+
Sbjct: 1606 WAILFSHPADYTPVCTTELGRVLNLIGEFEKRKCKVFALSCDGPESHKGWAKDVQKYAGV 1427

Query: 155  G---HMNITLLSDITKQISRDYGVL------LESAGIALRGLFIIDPNGVVKHLSVNDLP 205
                     +++D  + ++   G++       +   +  R +FII P+  +K   +    
Sbjct: 1426 DTDTKFPYPIIADEKRDLAVQLGMVDPAEKTKDGLPLTCRAVFIIGPDKKLKLSLLYPAT 1247

Query: 206  VGRSVEETLRLVKAFQFVETHGEVCPANWTP 236
             GR+ +E LR++ + Q   T     P NW P
Sbjct: 1246 TGRNFDEILRVLDSLQLTATKKVATPENWQP 1154
>14066
          Length = 1483

 Score = 27.7 bits (60), Expect = 5.0,   Method: Compositional matrix adjust.
 Identities = 22/72 (30%), Positives = 29/72 (40%)
 Frame = -2

Query: 51  GKSAFSTSSSFHTPAVTQHAPYFKGTAVVNGEFKELSLDDFKGKYLVLFFYPLDFTFVCP 110
            +  FS  S++ T  V Q               K +SLD  KGKY VL   PL+ T   P
Sbjct: 273 NRQNFSYRSNYKTRNVPQTMKL--------RLLKPISLDISKGKYTVLVLCPLNITI--P 124

Query: 111 TEIVAFSDKANE 122
             +    D  N+
Sbjct: 123 EMLYNIPDLNNK 88
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|7305605|ref|NP_038727.1| upstream binding protein 1
isoform b [Mus musculus]
         (504 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

21141                                                                 271   6e-73
05433                                                                 157   9e-39
32390                                                                  29   3.9  
>21141
          Length = 813

 Score =  271 bits (692), Expect = 6e-73,   Method: Compositional matrix adjust.
 Identities = 124/201 (61%), Positives = 163/201 (81%)
 Frame = +1

Query: 73  SPAVKLHDETLTYLNQGQSYEIRMLDNRKMGDMPELSGKLVKSIIRVVFHDRRLQYTEHQ 132
           SPAVK+++ETLTYLNQGQSYEI++   +K+GD+ E  GK ++SI+RV FH+RRLQY E +
Sbjct: 1   SPAVKMNEETLTYLNQGQSYEIKV---KKLGDLSEYQGKCLRSIVRVQFHERRLQYMEKE 171

Query: 133 QLEGWKWNRPGDRLLDLDIPMSVGIIDTRTNPSQLNAVEFLWDPAKRTSAFIQVHCISTE 192
           Q++ WK NRPG+R++D+DIP+S G++D   +PS++N  +F+WDP K T  + +VH ISTE
Sbjct: 172 QVDQWKANRPGERIVDVDIPLSYGLVDVILDPSKINQADFVWDPTKETGLYFRVHAISTE 351

Query: 193 FTPRKHGGEKGVPFRIQVDTFKQNENGEYTDHLHSASCQIKVFKPKGADRKQKNDREKME 252
           FT +KHGGEKGVPFR+QV+T+    +GE    LH+ASCQ+KVFKPKGADRK K DREKME
Sbjct: 352 FTAKKHGGEKGVPFRVQVETYTHG-DGE-GKLLHAASCQVKVFKPKGADRKHKTDREKME 525

Query: 253 KRTAHEKEKYQPSYDTTILTE 273
           KR+  EKEKYQPSY+ T+LTE
Sbjct: 526 KRSEAEKEKYQPSYECTVLTE 588
>05433
          Length = 1513

 Score =  157 bits (397), Expect = 9e-39,   Method: Compositional matrix adjust.
 Identities = 79/177 (44%), Positives = 112/177 (63%)
 Frame = +2

Query: 328 IQPSATTQETQQWLLKNRFSSYTRLFSNFSGADLLKLTKEDLVQICGAADGIRLYNSLKS 387
           I   AT+ E Q WL  +RFS+YTR+F +FSGADLL+L ++DL+QICG ADGIRL N+L+S
Sbjct: 29  IIVDATSAEVQGWLTFHRFSNYTRVFQHFSGADLLRLNRDDLIQICGLADGIRLNNALQS 208

Query: 388 RSVRPRLTIYVCQEQPSSTALXXXXXXXXXXXXXXXXXXXVYHAIYLEEMVASEVARKLA 447
           +SVRPRLTI++CQE  +                       VYHA+Y++ + A E+  KLA
Sbjct: 209 KSVRPRLTIFICQEPEA-----------------------VYHAVYMDSVGAHELKCKLA 319

Query: 448 SVFNIPFHQINQVYRQGPTGIHILVSDQMVQNFQDETCFLFSTVKAENNDGIHIILK 504
           S+F I    I  ++  GP+ IHILV+D+++ N QD++ F+    + E  D   I+LK
Sbjct: 320 SLFGIQASHIGDIFMIGPSSIHILVTDEVLLNTQDQSRFIVEGTREETGDKYRILLK 490
>32390
          Length = 423

 Score = 29.3 bits (64), Expect = 3.9,   Method: Compositional matrix adjust.
 Identities = 14/34 (41%), Positives = 20/34 (58%)
 Frame = +1

Query: 27  GQELGAGAYSMSDVLALPIFKQEDSSLSLEDEAK 60
            +ELGA    + D   LP   Q+++SLS ED+ K
Sbjct: 286 AEELGAPVIFLQDWTTLPQLLQQEASLSAEDKVK 387
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|20070420|ref|NP_613067.1| es1 protein [Mus musculus]
         (266 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

00206                                                                 269   7e-73
>00206
          Length = 1950

 Score =  269 bits (688), Expect = 7e-73,   Method: Compositional matrix adjust.
 Identities = 132/182 (72%), Positives = 150/182 (82%)
 Frame = +3

Query: 82  VPQMHVIDHTKGEPSERESRNVLAESARIARGKITSLAQLNAANHDAAIFPGGFGAAKNL 141
           + QMHVI+HTKGEP + + RNVL ESARIARGKI +L+ L  AN DA IFPGGFGAAKNL
Sbjct: 3   IDQMHVINHTKGEPMQPQ-RNVLIESARIARGKIEALSALQTANFDAVIFPGGFGAAKNL 179

Query: 142 STFAVDGKDCKVNKEVERVLKEFHGAKKPIGLCCIAPVLAAKVIKGVEVTVGHEQEEGGK 201
           S+FAVDG    VN +VERVLKEFHGA+KPIGLCCIAPVLAAKVI G EVTVG +QEEGG+
Sbjct: 180 SSFAVDGTAMTVNPDVERVLKEFHGAQKPIGLCCIAPVLAAKVIPGCEVTVGSDQEEGGR 359

Query: 202 WPYAGTAEAIKALGAKHCVKGVTEAHVDQKNKVVTTPAFMCETALHHIHDGIGAMVKNVL 261
           WPYAGTA AI ++ + H  K VTE HVD  NK+VTTPAFMCETA+H I+DGIG MVK+VL
Sbjct: 360 WPYAGTAGAIGSMDSTHVKKDVTECHVDSSNKIVTTPAFMCETAVHLIYDGIGGMVKSVL 539

Query: 262 EL 263
            L
Sbjct: 540 SL 545
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6753918|ref|NP_034371.1| AKT interacting protein [Mus
musculus]
         (292 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

21913                                                                 270   7e-73
31099                                                                  37   0.011
21443                                                                  36   0.018
02313                                                                  33   0.12 
02183                                                                  33   0.20 
37111                                                                  28   5.9  
26740                                                                  27   9.2  
>21913
          Length = 874

 Score =  270 bits (689), Expect = 7e-73,   Method: Compositional matrix adjust.
 Identities = 123/225 (54%), Positives = 164/225 (72%), Gaps = 1/225 (0%)
 Frame = +3

Query: 68  ASYGPFYLEYSLLAEFTLVVKQKLPGVYVQPSYRSALVWFGVIFIRHGLYQDGVFKFTVY 127
           + YGPF  EY+++AE+  + KQKLPGVYV PS +S L+W GV+F+R GLY+    +FT+ 
Sbjct: 6   SGYGPFLQEYTMMAEYNQLHKQKLPGVYVMPSAKSPLLWNGVMFLRQGLYEGCSLRFTLT 185

Query: 128 IPDNYPDGDCPRLLFDIPVFHPLVDPTSGELDVKRAFAKWRRNHNHIWQVLMYARRVFYK 187
           IPDNYPDGDCP L+F+ PVFHPLVDP SG++DVKRAF KWRRN NH+WQVLMYAR++FYK
Sbjct: 186 IPDNYPDGDCPDLVFEFPVFHPLVDPVSGKVDVKRAFPKWRRNVNHLWQVLMYARKIFYK 365

Query: 188 IDTTSPLNPEAAVLYEKDIQLFKSKVVDSVKVCTARLFDQPKIEDPYAISFSPWNPSVHD 247
           I+T +PLNPEAA LYE+D   F+  V +SV+    RL   P  +DP+A+ FSPW   VH 
Sbjct: 366 IETKAPLNPEAATLYEQDTDQFRQHVSESVQTAKQRLMQPPASDDPFALRFSPWTEPVHC 545

Query: 248 EAREKMLTQK-KPDEQHNKSVHVAGLSWVKPGSVQPFSKEEKTVA 291
           EA+ +ML  K +  E+ + +    G+SW++PGS Q F +++   A
Sbjct: 546 EAKRQMLHSKTRHSEERSANPRDLGMSWMRPGSTQVFVRDDSAPA 680
>31099
          Length = 748

 Score = 36.6 bits (83), Expect = 0.011,   Method: Compositional matrix adjust.
 Identities = 25/89 (28%), Positives = 45/89 (50%)
 Frame = +2

Query: 117 YQDGVFKFTVYIPDNYPDGDCPRLLFDIPVFHPLVDPTSGELDVKRAFAKWRRNHNHIWQ 176
           YQ GVF  T+  P +YP    P++ F   ++HP ++ ++G + +    ++W      I +
Sbjct: 224 YQGGVFFLTITFPADYP-FKPPKVAFTTKIYHPNIN-SNGSICLDILRSQWSPALT-ISK 394

Query: 177 VLMYARRVFYKIDTTSPLNPEAAVLYEKD 205
           VL+    +    +   PL PE A +Y+ D
Sbjct: 395 VLLSISSLLTDPNPDDPLVPEIARVYKND 481
>21443
          Length = 610

 Score = 35.8 bits (81), Expect = 0.018,   Method: Compositional matrix adjust.
 Identities = 26/97 (26%), Positives = 48/97 (49%)
 Frame = -1

Query: 113 RHGLYQDGVFKFTVYIPDNYPDGDCPRLLFDIPVFHPLVDPTSGELDVKRAFAKWRRNHN 172
           R   Y+ GVF  T+  P +YP    P++ F   ++HP ++ ++G + +    ++W     
Sbjct: 415 RDSAYEGGVFFLTISFPTDYPFKP-PKVSFTTRIYHPNIN-SNGSICLDILRSQWSPALT 242

Query: 173 HIWQVLMYARRVFYKIDTTSPLNPEAAVLYEKDIQLF 209
            I +VL+    +    +   PL PE A +Y+ D + F
Sbjct: 241 -ISKVLLSICSMLTDPNPDDPLVPEIARIYKTDREKF 134
>02313
          Length = 891

 Score = 33.1 bits (74), Expect = 0.12,   Method: Compositional matrix adjust.
 Identities = 34/116 (29%), Positives = 50/116 (43%), Gaps = 17/116 (14%)
 Frame = -1

Query: 106 WFGVIFIRHG-LYQDGVFKFTVYIPDNYPDGDCPRLLFDIPVFHPLV------------- 151
           W   IF   G LY+ G FK  +  P +YP    P + F   ++HP V             
Sbjct: 669 WEVAIFGPPGTLYEGGYFKAHMKFPADYPYSP-PSVRFITKMWHPNVYENGEVCISILHP 493

Query: 152 ---DPTSGELDVKRAFAKWRRNHNHIWQVLMYARRVFYKIDTTSPLNPEAAVLYEK 204
              DP SGEL  +R    W      +  +L+    +  + +T SP N +A+V+Y K
Sbjct: 492 PVDDPQSGELPSER----WNPTQT-VRTILLSIISLLNEPNTYSPANVDASVMYRK 340
>02183
          Length = 1456

 Score = 32.7 bits (73), Expect = 0.20,   Method: Compositional matrix adjust.
 Identities = 30/120 (25%), Positives = 55/120 (45%), Gaps = 9/120 (7%)
 Frame = -2

Query: 115  GLYQDGVFKFTVYIPDNYPDGDCPRLLFDIPVFHPLVDPTSGELDVKR---------AFA 165
            G +  G FKF + +P+ Y +   P+ +    ++HP +   +GE+ +            +A
Sbjct: 1167 GYWTGGKFKFDINVPEEY-NIVPPKAVCHTKIWHPNI-TEAGEICLSLLRQNSYDGLGWA 994

Query: 166  KWRRNHNHIWQVLMYARRVFYKIDTTSPLNPEAAVLYEKDIQLFKSKVVDSVKVCTARLF 225
              RR  + +W +      +   ++   PLN EAA  + +D + FK KV D ++    R F
Sbjct: 993  PTRRLKDVVWGLNSLFSDL---LNFEDPLNVEAAEHFARDKESFKIKVRDYIQAYAKR*F 823
>37111
          Length = 611

 Score = 27.7 bits (60), Expect = 5.9,   Method: Compositional matrix adjust.
 Identities = 26/102 (25%), Positives = 43/102 (42%), Gaps = 9/102 (8%)
 Frame = -1

Query: 117 YQDGVFKFTVYIPDNYPDGDCPRLLFDIPVFHPLVDPTSGE--LDVKRAFAKWRRNHNHI 174
           Y+ G F+  + IP+ YP  + P + F   ++HP V   +G   LD+ +            
Sbjct: 353 YEGGRFELDIRIPETYP-FNPPLVKFLTKIWHPNVSSVTGAICLDILK----------DQ 207

Query: 175 WQVLMYARRVFYKID----TTSPLNPEAAVL---YEKDIQLF 209
           W   M  R V   +        P +P+ AV+   Y+   +LF
Sbjct: 206 WAAAMTLRTVLLSLQALMAAAEPDDPQDAVVANQYKDHRELF 81
>26740
          Length = 404

 Score = 26.9 bits (58), Expect = 9.2,   Method: Compositional matrix adjust.
 Identities = 9/18 (50%), Positives = 13/18 (72%)
 Frame = +2

Query: 117 YQDGVFKFTVYIPDNYPD 134
           Y +G F+F VY P +YP+
Sbjct: 329 YANGAFEFDVYFPQDYPN 382
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|37718970|ref|NP_759013.2| hypothetical protein
LOC230249 [Mus musculus]
         (1840 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

14383                                                                 272   1e-72
15971                                                                 269   6e-72
29563                                                                  69   2e-11
32022                                                                  35   0.32 
18026                                                                  33   1.4  
>14383
          Length = 710

 Score =  272 bits (695), Expect = 1e-72,   Method: Compositional matrix adjust.
 Identities = 132/225 (58%), Positives = 170/225 (75%), Gaps = 1/225 (0%)
 Frame = +2

Query: 1094 KGAAFGFNVIATRAGEQLAPFLPQLVPRLYRYQFDPNLGIRQAMTSIWNALVTD-KSMVD 1152
            KG    F+   T + EQLAP++ Q+VPRLYRYQFDPN  I+QAM  IW+ALVTD K  VD
Sbjct: 2    KGQRLDFHDCYT-SREQLAPYMSQIVPRLYRYQFDPNPRIQQAMAGIWSALVTDNKKTVD 178

Query: 1153 KYLKEILQDLIKNLTSNMWRVRESSCLALNDLLRGRPLDDVIDKLPEMWETLFRVQDDIK 1212
             YLKEIL DL+KNLT+N WRVRESSC A+ DLLRGR LD +++ LPE+WE   RV+DDIK
Sbjct: 179  TYLKEILHDLLKNLTNNQWRVRESSCNAVTDLLRGRTLDTIVEDLPELWEQCLRVRDDIK 358

Query: 1213 ESVRKAAELALKTLSKVCVKMCDPAKGAAGQRTIAVLLPCLLDKGMMSPVTEVRALSINT 1272
            ESVR +A+ + KTLSKV +++CDP  G AG+R  + +LPCLL+  + + V EVRA+ ++T
Sbjct: 359  ESVRLSADQSCKTLSKVSIRICDPENGQAGERATSAVLPCLLNITLNTNVKEVRAIGLST 538

Query: 1273 LVKISKSAGAMLKPHAPKLIPALLESLSVLEPQVLNYLSLRATEQ 1317
            +++ISK AG +LKPH   L+ ALLE++S LEPQVLNYLS   + Q
Sbjct: 539  ILEISKKAGKLLKPHIHTLVVALLEAVSGLEPQVLNYLSFHTSSQ 673
>15971
          Length = 742

 Score =  269 bits (688), Expect = 6e-72,   Method: Compositional matrix adjust.
 Identities = 129/247 (52%), Positives = 179/247 (72%), Gaps = 2/247 (0%)
 Frame = -1

Query: 1242 GQRTIAVLLPCLLDKGMMSPVTEVRALSINTLVKISKSAGAMLKPHAPKLIPALLESLSV 1301
            G+R  + +LPCLL+  + + V EVRA+ ++T+++ISK AG +LKPH   L+ ALLE++S 
Sbjct: 742  GERATSAVLPCLLNITLNTNVKEVRAIGLSTILEISKKAGKLLKPHIHTLVVALLEAVSG 563

Query: 1302 LEPQVLNYLSLRATEQ-EKDVMDSA-RLSAAKSSPMMETINMCLQYLDVSVLGELVPRLC 1359
            LEPQVLNYLS   + Q  +D +D A R  A+KSSPMMET+N C+QY+D SVL ELVPRL 
Sbjct: 562  LEPQVLNYLSFHTSSQVTQDKLDKAHRG*ASKSSPMMETVNRCVQYVDESVLTELVPRLT 383

Query: 1360 ELIRSGVGLGTKGGCASVIVSLTTQCPQDLTPYSGKLMSALLSGLTDRNSVIQKSCAFAM 1419
            ELI+ G+G+GTK GC+S +VSL  QCP DL P++GKLM A L GL DRNS ++K+ A A+
Sbjct: 382  ELIKRGLGVGTKAGCSSFVVSLVHQCPHDLAPHAGKLMGAFLHGLNDRNSSVRKNYASAL 203

Query: 1420 GHLVRTSRDSSTEKLLQKLNGWYMEKDEPVYKTSCALTIHAIGRYSPDVLKNHAKEVLPL 1479
             HLV+  +D STEKL+ KL  WY++ +    + +C +T+HAI + +PD L+ HA   +PL
Sbjct: 202  AHLVKVGKDKSTEKLICKLKTWYLDHENESAQQACGVTLHAISQTAPDHLRRHASLAMPL 23

Query: 1480 AFLGMHE 1486
            AF  +H+
Sbjct: 22   AFFALHQ 2
>29563
          Length = 1310

 Score = 68.9 bits (167), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 33/50 (66%), Positives = 40/50 (80%)
 Frame = +1

Query: 3    TGSDSDQLERVFLRLGHAETDEQLQNIISKFLPPVLLKLSSTQEGVRKKV 52
             G  S  +ERVFLR G AETDEQL+N++ KFL PVLLKL+S++E VRKKV
Sbjct: 1021 NGVISVLVERVFLRFGSAETDEQLENVLGKFLAPVLLKLNSSEEAVRKKV 1170
>32022
          Length = 498

 Score = 35.0 bits (79), Expect = 0.32,   Method: Composition-based stats.
 Identities = 24/79 (30%), Positives = 39/79 (49%)
 Frame = -1

Query: 1156 KEILQDLIKNLTSNMWRVRESSCLALNDLLRGRPLDDVIDKLPEMWETLFRVQDDIKESV 1215
            K+ +  L+  L      VRES+CL+L  L   + +D ++D          R ++D   +V
Sbjct: 342  KDTVPRLVSLLEDEDRLVRESACLSLGFLQATKAVDHIVD----------RWRNDPISTV 193

Query: 1216 RKAAELALKTLSKVCVKMC 1234
            R+AAELAL  +     + C
Sbjct: 192  REAAELALSKMKIAEAQRC 136
>18026
          Length = 628

 Score = 32.7 bits (73), Expect = 1.4,   Method: Composition-based stats.
 Identities = 17/40 (42%), Positives = 21/40 (52%)
 Frame = -1

Query: 1422 LVRTSRDSSTEKLLQKLNGWYMEKDEPVYKTSCALTIHAI 1461
            + R S +S T K L+ LNG +     P YK  C LT  AI
Sbjct: 181  MARASENSHTNKPLKLLNGSHGPHTMPTYKVFCCLTNQAI 62
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6677659|ref|NP_033610.1| DnaJ (Hsp40) homolog,
subfamily C, member 2 [Mus musculus]
         (621 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

13422                                                                 269   2e-72
02324                                                                  60   3e-09
09629                                                                  58   1e-08
34504                                                                  47   3e-05
13998                                                                  46   4e-05
26984                                                                  43   4e-04
14550                                                                  37   0.023
09362                                                                  36   0.048
25991                                                                  35   0.071
14153                                                                  35   0.10 
07620                                                                  33   0.44 
11692                                                                  28   7.4  
>13422
          Length = 930

 Score =  269 bits (688), Expect = 2e-72,   Method: Compositional matrix adjust.
 Identities = 138/280 (49%), Positives = 178/280 (63%), Gaps = 2/280 (0%)
 Frame = +1

Query: 3   LLPSAAEGQGTAITHALTSASSVCQVEPVGRWFEAFVKRRNRNASTSFXXXXXXXXXXXX 62
           ++P A + + + +  ALT    V  VEP G+WF A+ +R +     SF            
Sbjct: 94  MIPHAEDDEVSEVFGALTPGD-VITVEPTGQWFSAYQQRVH--GRQSFHSSSSSEGEEEI 264

Query: 63  XXXXXXXXXXFPMLKTLDPKDWKNQDHYAVLGLGHVRYTATQRQIKAAHKAMVLKHHPDK 122
                       +L  L+PK+WK QDHYAVLGL  +RY AT   IK  ++  VL HHPDK
Sbjct: 265 EDVEESEEDH-TLLLGLNPKEWKKQDHYAVLGLSKLRYKATADHIKRIYRQKVLLHHPDK 441

Query: 123 RKAAGEPIKEGDNDYFTCITKAYEMLSDPVKRRAFNSVDPTFDNSVPSK-SEAKDNFFQV 181
           R+A G  ++ G+NDYF CI++AYE+L DPVKRR+F+SVDP FD +VPS   E KDNFF+V
Sbjct: 442 RRARGLHVENGENDYFLCISRAYEILGDPVKRRSFDSVDPEFDEAVPSLCQENKDNFFKV 621

Query: 182 FSPVFERNSRWSNKKNVPKLGDMNSSFEDVDAFYSFWYNFDSWREFSYLXXXXXXXXXXX 241
           F P FERN+RWSNKK VP+LGD N+ F+ V+AFY+FWY+FDSWREFSY            
Sbjct: 622 FRPAFERNARWSNKKKVPQLGDENTDFDHVNAFYNFWYSFDSWREFSYKDEEEKEKGENR 801

Query: 242 XXXXWIEKQNRATRAQR-KKEEMNRIRTLVDNAYSCDPRI 280
               WIEKQN++   ++ KKEE  R+R LVDNAY+ DPRI
Sbjct: 802 EERRWIEKQNKSGLVKKLKKEETARLRQLVDNAYTSDPRI 921
>02324
          Length = 2058

 Score = 60.1 bits (144), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 57/224 (25%), Positives = 92/224 (41%), Gaps = 32/224 (14%)
 Frame = +2

Query: 89  HYAVLGLGHVRYTATQRQIKAAHKAMVLKHHPDKRKAAGEPIKEGDNDYFTCITKAYEML 148
           HY VLG   V  +A    +K A++ + LK HPDK   + E         F  + +AYE+L
Sbjct: 107 HYEVLG---VERSADNDDLKKAYRKLALKFHPDKNPDSVEEATAQ----FRLVQQAYEIL 265

Query: 149 SDPVKRRAFN------------SVDPTFDNSV-----------PSKSEAKDNFFQVFSPV 185
           +DP +R  ++              D   DNS+               +    F+ V+  V
Sbjct: 266 TDPQERSWYDRHREAILRGGQGKGDKYEDNSLNLFQYFTSSCYSGFGDDDKGFYSVYREV 445

Query: 186 FERNS----RWSNKKN----VPKLGDMNSSFEDV-DAFYSFWYNFDSWREFSYLXXXXXX 236
           F+  S     + + K+     P+ GD  S +++V  AFY FW+ F + + + ++      
Sbjct: 446 FKTVSSEDYEFMDDKDSDFSFPEFGDSQSDYDEVVKAFYDFWHAFCTCKSYVWVEEYDTR 625

Query: 237 XXXXXXXXXWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRI 280
                     +E +N+  R   KKE    IR LV      D R+
Sbjct: 626 EAPDRRTRRLMEAENKKQRDAAKKERNEEIRALVAFVRKRDKRV 757
>09629
          Length = 394

 Score = 57.8 bits (138), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 23/49 (46%), Positives = 36/49 (73%)
 Frame = +3

Query: 554 WTTEEQKLLEQALKTYPVNTPERWEKIAEAVPGRTKKDCMRRYKELVEM 602
           WT  +Q + E AL+ +P  T +RW+KIAE + G+TK+DC+ R+K+L E+
Sbjct: 246 WTQNQQVIFEWALRHFPKGTDKRWDKIAEQISGKTKEDCIIRFKQLAEL 392

 Score = 28.9 bits (63), Expect = 6.5,   Method: Compositional matrix adjust.
 Identities = 18/57 (31%), Positives = 31/57 (54%)
 Frame = +3

Query: 453 NWSEDDLQLLIKAVNLFPAGTNSRWEVIANYMNIHSSSGVKRTAKDVISKAKSLQKL 509
           +W+++   +   A+  FP GT+ RW+ IA  +     SG  +T +D I + K L +L
Sbjct: 243 SWTQNQQVIFEWALRHFPKGTDKRWDKIAEQI-----SG--KTKEDCIIRFKQLAEL 392
>34504
          Length = 509

 Score = 46.6 bits (109), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 21/51 (41%), Positives = 31/51 (60%)
 Frame = -2

Query: 435 QASKNAEKXXXXXXXXXKNWSEDDLQLLIKAVNLFPAGTNSRWEVIANYMN 485
           ++S + ++          +WSE++L LL KAVN FP GT  RWE IAN ++
Sbjct: 208 ESSNSVDQQSSQSHAKGGDWSEEELVLLAKAVNKFPGGTPKRWEKIANMLD 56

 Score = 36.6 bits (83), Expect = 0.033,   Method: Compositional matrix adjust.
 Identities = 17/42 (40%), Positives = 24/42 (57%)
 Frame = -2

Query: 554 WTTEEQKLLEQALKTYPVNTPERWEKIAEAVPGRTKKDCMRR 595
           W+ EE  LL +A+  +P  TP+RWEKIA  +     + C  R
Sbjct: 151 WSEEELVLLAKAVNKFPGGTPKRWEKIANMLDRSVDEVCPSR 26
>13998
          Length = 1075

 Score = 46.2 bits (108), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 24/78 (30%), Positives = 44/78 (56%)
 Frame = +1

Query: 82  KDWKNQDHYAVLGLGHVRYTATQRQIKAAHKAMVLKHHPDKRKAAGEPIKEGDNDYFTCI 141
           K  K +D+Y +LG+      AT+ +IK A++   L HHPD+   +   +++ +   F  +
Sbjct: 187 KKSKRKDYYKILGISR---NATEDEIKKAYRKKALVHHPDRHANSSADVRKDEELKFKEV 357

Query: 142 TKAYEMLSDPVKRRAFNS 159
            +AY +LSD  K+  ++S
Sbjct: 358 GEAYAILSDGAKKTRYDS 411
>26984
          Length = 1107

 Score = 42.7 bits (99), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 25/75 (33%), Positives = 41/75 (54%)
 Frame = -2

Query: 85  KNQDHYAVLGLGHVRYTATQRQIKAAHKAMVLKHHPDKRKAAGEPIKEGDNDYFTCITKA 144
           K +D Y++LGL   R  A+   IK  ++   +  HPDK +   EP   G  + F  +  A
Sbjct: 524 KGKDPYSILGL---RADASDEDIKRYYRRQAVLVHPDKNQ---EP---GAEEAFKILGHA 372

Query: 145 YEMLSDPVKRRAFNS 159
           +EM+ DP KR+ +++
Sbjct: 371 FEMIGDPTKRKEYDT 327
>14550
          Length = 1395

 Score = 37.0 bits (84), Expect = 0.023,   Method: Compositional matrix adjust.
 Identities = 24/73 (32%), Positives = 39/73 (53%)
 Frame = -1

Query: 86   NQDHYAVLGLGHVRYTATQRQIKAAHKAMVLKHHPDKRKAAGEPIKEGDNDYFTCITKAY 145
             +D Y +LG   V  +A  +QIK A++ +  + HPDK +   E  +      F  +  AY
Sbjct: 1140 GRDFYKILG---VSKSADTKQIKRAYRKIAKELHPDKNRDDPEAEQR-----FQDLGAAY 985

Query: 146  EMLSDPVKRRAFN 158
            E+LSD  KR+ ++
Sbjct: 984  EVLSDEEKRKVYD 946
>09362
          Length = 925

 Score = 35.8 bits (81), Expect = 0.048,   Method: Compositional matrix adjust.
 Identities = 18/53 (33%), Positives = 26/53 (49%)
 Frame = +2

Query: 547 PCIDSTPWTTEEQKLLEQALKTYPVNTPERWEKIAEAVPGRTKKDCMRRYKEL 599
           P I   PWT  E K L   L+   ++    W K  + +PGRT    ++RY+ L
Sbjct: 236 PNISGQPWTYNEDKTL---LEQVAIHGRGNWVKCLKELPGRTDNQILQRYRRL 385
>25991
          Length = 847

 Score = 35.4 bits (80), Expect = 0.071,   Method: Compositional matrix adjust.
 Identities = 22/56 (39%), Positives = 29/56 (51%), Gaps = 2/56 (3%)
 Frame = -1

Query: 554 WTTEEQKLLEQALKTYPVNTPE--RWEKIAEAVPGRTKKDCMRRYKELVEMVKAKK 607
           WT EEQK L++ L  YP    E  RW KIA A   RT +    R ++  E ++  K
Sbjct: 238 WTPEEQKRLDELLVQYPPEEVEARRWRKIAAAFGDRTPQQIASRVQKYFEKLERNK 71
>14153
          Length = 419

 Score = 34.7 bits (78), Expect = 0.10,   Method: Composition-based stats.
 Identities = 14/21 (66%), Positives = 19/21 (90%)
 Frame = +3

Query: 584 VPGRTKKDCMRRYKELVEMVK 604
           +P R+KKDCM+RYKEL E+V+
Sbjct: 3   IPNRSKKDCMKRYKELCEIVR 65
>07620
          Length = 1775

 Score = 32.7 bits (73), Expect = 0.44,   Method: Compositional matrix adjust.
 Identities = 17/48 (35%), Positives = 22/48 (45%)
 Frame = +3

Query: 133 GDNDYFTCITKAYEMLSDPVKRRAFNSVDPTFDNSVPSKSEAKDNFFQ 180
           G  D F  I  AY +LSDP KRR ++   P         SE  +  F+
Sbjct: 207 GATDAFKKIGNAYSVLSDPDKRRKYDVYGPELQQPSQHHSEYSNGGFE 350
>11692
          Length = 880

 Score = 28.5 bits (62), Expect = 7.4,   Method: Compositional matrix adjust.
 Identities = 27/83 (32%), Positives = 41/83 (49%), Gaps = 14/83 (16%)
 Frame = +3

Query: 482 NYMNIH-----SSSGVKRTAKDVISKAKSLQKLDPHQKDDINKKAFDKFKKEHGVASQA- 535
           N  NIH     S+S +K    D + +A S +K+D   K +  K+A+ KFK +H + S + 
Sbjct: 429 NNHNIHNEIVISNSTIKAREID*LLEADS-KKIDG*TKANYIKEAYIKFKIQHSIISHSN 605

Query: 536 ------DSAAPSERFEG--PCID 550
                 +   PSE FE   PC +
Sbjct: 606 *FLSIENVT*PSEMFETAVPCCN 674
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|78190507|ref|NP_001030303.1| exportin 1, CRM1 homolog
[Mus musculus]
         (1071 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

09530                                                                 269   3e-72
38734                                                                  32   1.3  
21946                                                                  31   3.4  
31761                                                                  30   4.2  
15337                                                                  30   5.7  
>09530
          Length = 971

 Score =  269 bits (688), Expect = 3e-72,   Method: Compositional matrix adjust.
 Identities = 128/179 (71%), Positives = 151/179 (84%), Gaps = 1/179 (0%)
 Frame = +2

Query: 894  LQILFTLLQNVAQEEAAAQSFYQTYFCDILQHIFSVVTDTSHTAGLTMHASILAYMFNLV 953
            L IL+TLLQN+A EE AAQSFYQTYF DILQH+FSV+TD+SHTAGLTM A+ILA MF  +
Sbjct: 2    LDILYTLLQNIAGEEVAAQSFYQTYFTDILQHLFSVITDSSHTAGLTMQATILATMFVAL 181

Query: 954  EEGKISTPLNPGN-PVNNQMFIQDYVANLLKSAFPHLQDAQVKLFVTGLFSLNQDIPAFK 1012
            E  KI+ PL+P + P  N  +IQD++ NLLK+AFPHL + Q+KLF+ GLFS +QD  AFK
Sbjct: 182  ESNKITAPLSPNHAPAQNVAYIQDFLLNLLKTAFPHLNEPQIKLFIEGLFSFDQDFNAFK 361

Query: 1013 EHLRDFLVQIKEFAGEDTSDLFLEERETALRQAQEEKHKLQMSVPGILNPHEIPEEMCD 1071
            EHLRDFLVQI+EFAGED SDLFLEERETA+RQAQ+EK K+QM+VPGIL PHEIPEEM D
Sbjct: 362  EHLRDFLVQIREFAGEDMSDLFLEERETAIRQAQDEKRKVQMAVPGILGPHEIPEEMQD 538
>38734
          Length = 605

 Score = 32.0 bits (71), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 19/59 (32%), Positives = 34/59 (57%), Gaps = 1/59 (1%)
 Frame = +3

Query: 976  DYVANLLKSAFPHLQDAQVKL-FVTGLFSLNQDIPAFKEHLRDFLVQIKEFAGEDTSDL 1033
            +Y  NL K +   +Q AQ +L  +  + +LN ++ A K+HL + L Q+K+   ED  ++
Sbjct: 207  EYFRNLYKRSEVAVQQAQEELAMLRSVKALNVELIASKQHLMEELAQVKKLRKEDQEEM 383
>21946
          Length = 569

 Score = 30.8 bits (68), Expect = 3.4,   Method: Composition-based stats.
 Identities = 13/42 (30%), Positives = 23/42 (54%), Gaps = 3/42 (7%)
 Frame = -2

Query: 559 WKFLKTVV---NKLFEFMHETHDGVQDMACDTFIKIAQKCRR 597
           W  L T++   ++   F H+TH  V+D  C  +  I ++C+R
Sbjct: 196 WCLLSTIIQTCHQRLRFEHDTHCAVRDSCCREWYVIFRRCQR 71
>31761
          Length = 1165

 Score = 30.4 bits (67), Expect = 4.2,   Method: Compositional matrix adjust.
 Identities = 14/46 (30%), Positives = 25/46 (54%)
 Frame = -2

Query: 588  FIKIAQKCRRHFVQVQVGEVMPFIDEILNNINTIICDLQPQQVHTF 633
             +K   K    ++Q +V + +PFID+ L N+  +IC +    VH +
Sbjct: 1128 LLKFINKVDDPYIQCKVSQTLPFIDQHLVNLR*LICYISNLGVHIW 991
>15337
          Length = 860

 Score = 30.0 bits (66), Expect = 5.7,   Method: Composition-based stats.
 Identities = 22/94 (23%), Positives = 39/94 (41%), Gaps = 5/94 (5%)
 Frame = +1

Query: 381 YRESPFSTSASP-----LLSGSQHFDIPPRRQLYLTVLSKVRLLMVSRMAKPEEVLVVEN 435
           +++   + S+SP     L SG QH    P + L++  +S + L + +R            
Sbjct: 112 WKDHTVTRSSSPPVTMYLPSGDQHTHNKPPK*LFIVPISSMEL*LNTRRCPS*PTTARYR 291

Query: 436 DQGEVVREFMKDTDSINLYKNMRETLVYLTHLDY 469
           +QGE     M    +   Y  +R  LV   + +Y
Sbjct: 292 EQGEKANSLMAPVPTTQRYNGLRVLLVLQVNTEY 393
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|160707894|ref|NP_033788.3| aldo-keto reductase family
1, member B1 [Mus musculus]
         (316 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

17411                                                                 265   2e-71
00500                                                                 167   8e-46
09575                                                                 162   1e-40
02477                                                                 119   1e-27
31792                                                                 110   7e-25
20851                                                                  72   5e-23
08973                                                                  91   4e-19
26455                                                                  52   5e-16
24743                                                                  40   0.001
13564                                                                  32   0.24 
17872                                                                  31   0.55 
>17411
          Length = 1104

 Score =  265 bits (676), Expect = 2e-71,   Method: Compositional matrix adjust.
 Identities = 139/313 (44%), Positives = 191/313 (61%), Gaps = 2/313 (0%)
 Frame = -3

Query: 5    LELNNGTKMPTLGLGTWKSPPGQVTEAVKVAIDLGYRHIDCAQVYQNEKEVGVALQEKLK 64
            ++LNNG ++P LGLGT+ S   +   A+K AID+GYRHID A   QNE EVG A+++K+ 
Sbjct: 1060 VKLNNGYEIPILGLGTYTSKDNEGEIAIKXAIDVGYRHIDTAYFXQNEFEVGKAIRDKIA 881

Query: 65   EQVVKRQDLFIVSKLWCTFHDKSMVKGAFQKTXXXXXXXXXXXXXIHWPTGFK--PGPDY 122
            E VV+R+D+F+V+KLW   HD  +V+ A +K              IH P G+K       
Sbjct: 880  EGVVQREDIFLVTKLWNIHHDPKLVESACRKQLALLCMDYIDLYLIHQPVGYKFIDEETL 701

Query: 123  FPLDASGNVIPSDTDFVDTWTAMEQLVDEGLVKTIGVSNFNPLQIERILNKPGLKYKPAV 182
             P DA+  +  SD D++DT+ AMEQLV  GLV++IGVSNFN  Q+ R++N    + KP  
Sbjct: 700  VPKDANNELQLSDVDYLDTYKAMEQLVKIGLVRSIGVSNFNSEQLLRVIN--NCEIKPVT 527

Query: 183  NQIECHPYLTQEKLIEYCHSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKYN 242
            NQ+EC P + Q+KLI +C   G+ +TAY PLG P     KPE    L  P +KAIA KY 
Sbjct: 526  NQVECSPAINQKKLIAFCKQHGVTLTAYRPLGKPQPDQNKPE---YLYSPEVKAIAQKYK 356

Query: 243  KTTAQVLIRFPIQRNLVVIPKSVTPVRIAENLKVFDFEVSSEDMATLLSYNRNWRVCALM 302
            K+  QV++R+ ++   + IPKS  P RIAEN  +FDFE+++E+   L  YN   R   + 
Sbjct: 355  KSAPQVILRYLVELGTLPIPKSSNPGRIAENFNIFDFELTAEEKCVLDGYNTGERNVPMT 176

Query: 303  SCAKHKDYPFHAE 315
            S   HK YPF  E
Sbjct: 175  SLKHHKYYPFAIE 137
>00500
          Length = 730

 Score =  167 bits (424), Expect(2) = 8e-46,   Method: Compositional matrix adjust.
 Identities = 83/215 (38%), Positives = 128/215 (59%), Gaps = 4/215 (1%)
 Frame = +2

Query: 10  GTKMPTLGLGTW---KSPPGQVTEAVKVAIDLGYRHIDCAQVYQNEKEVGVALQEKLKEQ 66
           G  MP +  GTW   +S  G+V   VK A++ GY H+D A VY NE EVG A+ + ++E 
Sbjct: 5   GQLMPVVAYGTWTVWQSKAGEVYRGVKTALEAGYGHVDTAWVYDNEHEVGQAVADVIQEG 184

Query: 67  VVKRQDLFIVSKLWCTFHDKSMVKGAFQKTXXXXXXXXXXXXXIHWPTGFK-PGPDYFPL 125
            + R D+FI +K+W T+H +  VK   +K+             +H+PT FK    D FP 
Sbjct: 185 SLTRGDIFITTKIWDTYHSRERVKLNVEKSLAKLKLSYVDLVLMHYPTSFKDTDDDNFPK 364

Query: 126 DASGNVIPSDTDFVDTWTAMEQLVDEGLVKTIGVSNFNPLQIERILNKPGLKYKPAVNQI 185
              G +I S+ D +DTW  +E  V  GLV+ IGVSNFN  QI+R+++   +  KP   Q+
Sbjct: 365 GPDGKIIYSNHDLLDTWKGLEDCVRAGLVRNIGVSNFNSQQIKRVVDAASI--KPCNLQV 538

Query: 186 ECHPYLTQEKLIEYCHSKGIVVTAYSPLGSPDRPW 220
           E +P ++ E+L+++  S+G+ V++Y+PLG+P R +
Sbjct: 539 EINPTMSNERLVKFAESQGLTVSSYAPLGAPGRKY 643

 Score = 33.9 bits (76), Expect(2) = 8e-46,   Method: Compositional matrix adjust.
 Identities = 14/28 (50%), Positives = 20/28 (71%)
 Frame = +3

Query: 225 DPSLLEDPRIKAIAAKYNKTTAQVLIRF 252
           DP  +EDP +  IA+K  KT AQV++R+
Sbjct: 645 DPCAIEDPVVTGIASKKGKTPAQVILRW 728
>09575
          Length = 734

 Score =  162 bits (411), Expect = 1e-40,   Method: Compositional matrix adjust.
 Identities = 77/186 (41%), Positives = 121/186 (65%), Gaps = 1/186 (0%)
 Frame = +1

Query: 110 IHWPTGFK-PGPDYFPLDASGNVIPSDTDFVDTWTAMEQLVDEGLVKTIGVSNFNPLQIE 168
           +H+PT FK    D FP    G +I S+ D +DTW  +E  V  GLV+ IGVSNFN  QI+
Sbjct: 28  MHYPTSFKDTDDDNFPKGPDGKIIYSNHDLLDTWKGLEDCVXAGLVRNIGVSNFNSQQIK 207

Query: 169 RILNKPGLKYKPAVNQIECHPYLTQEKLIEYCHSKGIVVTAYSPLGSPDRPWAKPEDPSL 228
           R+++   +K  P   Q+E +P ++ E+L+++  S+G+ V++Y+PLG+P RPW +  DP  
Sbjct: 208 RVVDAASIK--PCNLQVEINPTMSNERLVKFAESQGLTVSSYAPLGAPGRPWKESTDPCA 381

Query: 229 LEDPRIKAIAAKYNKTTAQVLIRFPIQRNLVVIPKSVTPVRIAENLKVFDFEVSSEDMAT 288
           +EDP +  IA+K  KT AQV++R+ +QR + V  KS+   RI +N+ VF+FE+S ++M  
Sbjct: 382 IEDPVVTGIASKKGKTPAQVILRWLLQRGVCVCVKSLNVDRIRQNIDVFNFELSEDEMTQ 561

Query: 289 LLSYNR 294
           +   N+
Sbjct: 562 MSGLNK 579
>02477
          Length = 1091

 Score =  119 bits (299), Expect = 1e-27,   Method: Compositional matrix adjust.
 Identities = 71/190 (37%), Positives = 101/190 (53%)
 Frame = +1

Query: 110 IHWPTGFKPGPDYFPLDASGNVIPSDTDFVDTWTAMEQLVDEGLVKTIGVSNFNPLQIER 169
           IHWP   K  P     DA         + + +W  MEQL  EG +K IGVSNF    +E 
Sbjct: 76  IHWPGTQKLQPH----DARHKA-----NRLASWADMEQLHKEGKLKAIGVSNFLQHHLEE 228

Query: 170 ILNKPGLKYKPAVNQIECHPYLTQEKLIEYCHSKGIVVTAYSPLGSPDRPWAKPEDPSLL 229
           IL    +K  PAV QIE HP+L Q  L+ +C    I   AYS LG+        ++  LL
Sbjct: 229 ILAVCSVK--PAVLQIEFHPHLVQSNLLSWCTQNTIHFQAYSSLGTT------SDNNKLL 384

Query: 230 EDPRIKAIAAKYNKTTAQVLIRFPIQRNLVVIPKSVTPVRIAENLKVFDFEVSSEDMATL 289
            D  +++IA++YN+T AQ+L+ + +Q+ + V+PKS     I EN ++FDF +   DM  L
Sbjct: 385 TDQTVQSIASRYNRTPAQILLHWAVQQGVGVLPKSTNQKHIEENGEIFDFTLEDSDMQAL 564

Query: 290 LSYNRNWRVC 299
            S + +   C
Sbjct: 565 SSLHSDTHYC 594
>31792
          Length = 377

 Score =  110 bits (275), Expect = 7e-25,   Method: Compositional matrix adjust.
 Identities = 53/124 (42%), Positives = 80/124 (64%), Gaps = 2/124 (1%)
 Frame = -3

Query: 145 MEQLVDEGLVKTIGVSNFNPLQIERILNKPGLKYKPAVNQIECHPYLTQEKLIEYCHSKG 204
           +E+LV EG ++++G+SNFN +Q++ I        KP +NQ+ECH YL Q++L  +C  + 
Sbjct: 366 LEKLVQEGKIRSLGISNFNSVQVDLI--NFVATVKPVINQVECHAYLAQKELQAFCQKRN 193

Query: 205 IVVTAYSPLGSPDRP--WAKPEDPSLLEDPRIKAIAAKYNKTTAQVLIRFPIQRNLVVIP 262
           I + A++PLGSP RP       DP LLE+P + +I  KY KT AQVL+R   QR + ++ 
Sbjct: 192 IFLQAFAPLGSPGRPEHMVTDGDPVLLEEPVLASIGEKYKKTPAQVLLRNLFQRGMAMVA 13

Query: 263 KSVT 266
           KS +
Sbjct: 12  KSCS 1
>20851
          Length = 408

 Score = 71.6 bits (174), Expect(2) = 5e-23,   Method: Compositional matrix adjust.
 Identities = 38/86 (44%), Positives = 48/86 (55%), Gaps = 5/86 (5%)
 Frame = +2

Query: 40  YRHIDCAQVYQNEKEVGVALQEKLKEQVVKRQDLFIVSKLWCTFHDKSMVKGAFQKTXXX 99
           YRH D A VY+ EK VG  +  K+++  VKR+DLFIVSKLW T H  S V+ + ++T   
Sbjct: 2   YRHFDTAWVYETEKAVGEGIARKIQDGTVKREDLFIVSKLWNTCH--SRVEASLRETLNN 175

Query: 100 XXXXXXXXXXIHWPTGFK-----PGP 120
                     IHWP  FK     PGP
Sbjct: 176 LQLGYLDLYLIHWPIAFKKVENPPGP 253

 Score = 53.5 bits (127), Expect(2) = 5e-23,   Method: Compositional matrix adjust.
 Identities = 24/42 (57%), Positives = 32/42 (76%)
 Frame = +1

Query: 133 PSDTDFVDTWTAMEQLVDEGLVKTIGVSNFNPLQIERILNKP 174
           P D DFVDT+  ME+LVD+ LV ++GVSNFN  Q+ R+L+ P
Sbjct: 277 PVDHDFVDTYKDMEKLVDQRLVNSLGVSNFNTHQLTRLLSVP 402
>08973
          Length = 567

 Score = 91.3 bits (225), Expect = 4e-19,   Method: Compositional matrix adjust.
 Identities = 50/129 (38%), Positives = 66/129 (51%), Gaps = 2/129 (1%)
 Frame = -3

Query: 189 PYLTQEKLIEYCHSKGIVVTAYSPLGSPD--RPWAKPEDPSLLEDPRIKAIAAKYNKTTA 246
           P   Q KL  +    GIV+ AY PL  P   R W     P  L D R + +A KY +T A
Sbjct: 565 PAFQQHKLRAHAKKHGIVICAYCPLARPQPARHW-----PPFLYDERAQQLAKKYGRTAA 401

Query: 247 QVLIRFPIQRNLVVIPKSVTPVRIAENLKVFDFEVSSEDMATLLSYNRNWRVCALMSCAK 306
           Q+ + + IQ  +V +PKS    RIAEN   FDFE+  EDM  +  Y+ N R       + 
Sbjct: 400 QICLXYLIQSGVVPLPKSSNKKRIAENFNCFDFELMPEDMLAMEKYHTNVRTVPFSGMSS 221

Query: 307 HKDYPFHAE 315
           H+ YPF+ E
Sbjct: 220 HQYYPFNDE 194
>26455
          Length = 466

 Score = 51.6 bits (122), Expect(2) = 5e-16,   Method: Compositional matrix adjust.
 Identities = 24/46 (52%), Positives = 33/46 (71%)
 Frame = -3

Query: 1   MASHLELNNGTKMPTLGLGTWKSPPGQVTEAVKVAIDLGYRHIDCA 46
           +A  ++LNNG ++P LGLGT+ S   +   A+K AID+GYRHID A
Sbjct: 269 LAPTVKLNNGYEIPILGLGTYTSKDNEGEIAIKHAIDVGYRHIDTA 132

 Score = 50.1 bits (118), Expect(2) = 5e-16,   Method: Compositional matrix adjust.
 Identities = 21/37 (56%), Positives = 30/37 (81%)
 Frame = -2

Query: 49  YQNEKEVGVALQEKLKEQVVKRQDLFIVSKLWCTFHD 85
           YQNE EVG A+++K+ E VV+R+D+F+V+KLW   HD
Sbjct: 126 YQNEFEVGKAIRDKIAEGVVQREDIFLVTKLWNIHHD 16
>24743
          Length = 342

 Score = 40.0 bits (92), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 25/62 (40%), Positives = 30/62 (48%)
 Frame = +3

Query: 110 IHWPTGFKPGPDYFPLDASGNVIPSDTDFVDTWTAMEQLVDEGLVKTIGVSNFNPLQIER 169
           IHWP   K  P     DA         + + +W  MEQL  EG +K IGVSNF    +E 
Sbjct: 99  IHWPGTQKLQPH----DAR-----HKANRLXSWADMEQLHKEGKLKAIGVSNFLQHHLEE 251

Query: 170 IL 171
           IL
Sbjct: 252 IL 257
>13564
          Length = 842

 Score = 32.3 bits (72), Expect = 0.24,   Method: Compositional matrix adjust.
 Identities = 15/44 (34%), Positives = 28/44 (63%)
 Frame = +1

Query: 142 WTAMEQLVDEGLVKTIGVSNFNPLQIERILNKPGLKYKPAVNQI 185
           W A+E LVD+  V +IGV++ +  +++++      K KP +NQ+
Sbjct: 127 WKALEDLVDQERVLSIGVADLDKHKLDQLYQ--WAKVKPRINQV 252
>17872
          Length = 700

 Score = 31.2 bits (69), Expect = 0.55,   Method: Compositional matrix adjust.
 Identities = 19/56 (33%), Positives = 32/56 (57%), Gaps = 1/56 (1%)
 Frame = -1

Query: 1   MASHLELNNGTKMPTLGLGTWKSPPGQVTEAVKVAIDLGYRHIDCAQVYQ-NEKEV 55
           + +  +L N  K+  + L  +K  P    EAVK+A  LG ++++C+ + Q N KEV
Sbjct: 544 VGTQSDLRNDVKV-LIELAKYKEKPVSEEEAVKMADQLGAQYVECSALTQKNLKEV 380
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|148747526|ref|NP_033031.2| RAB7, member RAS oncogene
family [Mus musculus]
         (207 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

17511                                                                 263   4e-71
13745                                                                 237   3e-63
12339                                                                 204   3e-53
14456                                                                 202   1e-52
11257                                                                 149   5e-37
08428                                                                 137   2e-33
05468                                                                 124   3e-29
34468                                                                 111   2e-25
26083                                                                 100   6e-22
07465                                                                 100   6e-22
33374                                                                  99   9e-22
13901                                                                  97   4e-21
01972                                                                  86   1e-20
07580                                                                  75   9e-17
33794                                                                  82   2e-16
34359                                                                  75   2e-14
30760                                                                  72   1e-13
11728                                                                  72   1e-13
00858                                                                  72   2e-13
01398                                                                  70   5e-13
13750                                                                  70   5e-13
19656                                                                  69   2e-12
33380                                                                  69   2e-12
19006                                                                  69   2e-12
00552                                                                  68   3e-12
35581                                                                  67   4e-12
32723                                                                  66   1e-11
27191                                                                  59   5e-10
26536                                                                  60   7e-10
01095                                                                  56   9e-09
19046                                                                  55   2e-08
24619                                                                  54   7e-08
31291                                                                  51   3e-07
29380                                                                  50   6e-07
10708                                                                  36   1e-06
34597                                                                  47   6e-06
18509                                                                  46   1e-05
09204                                                                  45   2e-05
14775                                                                  44   6e-05
31932                                                                  41   4e-04
25618                                                                  39   0.001
05634                                                                  37   0.004
29461                                                                  36   0.010
14119                                                                  34   0.045
33605                                                                  33   0.099
08153                                                                  33   0.10 
10862                                                                  30   0.61 
09827                                                                  30   0.66 
11378                                                                  29   1.3  
06994                                                                  28   3.0  
14677                                                                  27   3.9  
28453                                                                  27   6.6  
14989                                                                  26   9.8  
>17511
          Length = 483

 Score =  263 bits (671), Expect = 4e-71,   Method: Compositional matrix adjust.
 Identities = 124/129 (96%), Positives = 127/129 (98%)
 Frame = -3

Query: 1   MTSRKKVLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQ 60
           M SRKKVLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQ
Sbjct: 388 MASRKKVLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQ 209

Query: 61  IWDTAGQERFQSLGVAFYRGADCCVLVFDVTAPNTFKTLDSWRDEFLIQASPRDPENFPF 120
           IWDTAGQERFQSLGVAFYRGADCCVLVFDVT PNTF++LDSWRDEFLIQASPRDPENFPF
Sbjct: 208 IWDTAGQERFQSLGVAFYRGADCCVLVFDVTMPNTFRSLDSWRDEFLIQASPRDPENFPF 29

Query: 121 VVLGNKIDL 129
           VV+GNKIDL
Sbjct: 28  VVIGNKIDL 2
>13745
          Length = 1045

 Score =  237 bits (604), Expect = 3e-63,   Method: Compositional matrix adjust.
 Identities = 107/141 (75%), Positives = 126/141 (89%)
 Frame = +2

Query: 67  QERFQSLGVAFYRGADCCVLVFDVTAPNTFKTLDSWRDEFLIQASPRDPENFPFVVLGNK 126
           QERFQSLGVAFYRGADCCVLV+DVTAPN+FK LDSWRDEFLIQASPRDPE+FPFVVLGNK
Sbjct: 2   QERFQSLGVAFYRGADCCVLVYDVTAPNSFKNLDSWRDEFLIQASPRDPEHFPFVVLGNK 181

Query: 127 IDLENRQVATKRAQAWCYSKNNIPYFETSAKEAINVEQAFQTIARNALKQETEVELYNEF 186
           +DL+NRQV+T+RAQ WC SKN+IPY+ETSAKE INVE AFQTIA+NAL+QETE EL N+F
Sbjct: 182 VDLDNRQVSTRRAQQWCQSKNDIPYYETSAKEGINVEMAFQTIAKNALEQETEAELINDF 361

Query: 187 PEPIKLDKNDRAKASAESCSC 207
           P+ I+L+  +    +A++C C
Sbjct: 362 PDQIRLNSENNRPGNADNCQC 424
>12339
          Length = 578

 Score =  204 bits (518), Expect = 3e-53,   Method: Compositional matrix adjust.
 Identities = 97/141 (68%), Positives = 114/141 (80%)
 Frame = -2

Query: 67  QERFQSLGVAFYRGADCCVLVFDVTAPNTFKTLDSWRDEFLIQASPRDPENFPFVVLGNK 126
           QERFQSLGVAFYRGADCC+LV+DVT   TF +LDSW+ EFL QASPRDPE+FPFVV+GNK
Sbjct: 577 QERFQSLGVAFYRGADCCILVYDVTEXKTFDSLDSWQREFLNQASPRDPEHFPFVVIGNK 398

Query: 127 IDLENRQVATKRAQAWCYSKNNIPYFETSAKEAINVEQAFQTIARNALKQETEVELYNEF 186
           IDL+NR V  KR Q WC +K  IPYFETSAKEAINVEQAFQT+A+NAL QE+EVE+ ++F
Sbjct: 397 IDLDNRVVTAKRGQGWCSTKGGIPYFETSAKEAINVEQAFQTVAKNALAQESEVEI-DDF 221

Query: 187 PEPIKLDKNDRAKASAESCSC 207
           P  I+L  +D      E C+C
Sbjct: 220 PSEIRLSNDD--SRPRERCAC 164
>14456
          Length = 1867

 Score =  202 bits (513), Expect = 1e-52,   Method: Compositional matrix adjust.
 Identities = 100/199 (50%), Positives = 132/199 (66%), Gaps = 3/199 (1%)
 Frame = -1

Query: 7    VLLKVII---LGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQIWD 63
            V LK+ +   L   GVGK+SLMN++V+ KF  Q   TIG +FL K+V+VDD   TMQIWD
Sbjct: 1153 VWLKITLDKQLKQGGVGKSSLMNRFVSNKFDAQSFHTIGVEFLNKDVVVDDETYTMQIWD 974

Query: 64   TAGQERFQSLGVAFYRGADCCVLVFDVTAPNTFKTLDSWRDEFLIQASPRDPENFPFVVL 123
            TAGQERF+SL   FYRGADCC+L F V +  +F+ L  WR EFL  A  +D   FPFVVL
Sbjct: 973  TAGQERFKSLRTPFYRGADCCLLTFSVDSMQSFRNLSMWRKEFLYYADIQDGVTFPFVVL 794

Query: 124  GNKIDLENRQVATKRAQAWCYSKNNIPYFETSAKEAINVEQAFQTIARNALKQETEVELY 183
            GNKID+E RQV  + A++WC + +N PYFETSAK+A NVE+AF    +   + E + E+ 
Sbjct: 793  GNKIDVEGRQVTNEEARSWCTANSNAPYFETSAKDATNVEKAFLAAVQRLREVEDQQEVK 614

Query: 184  NEFPEPIKLDKNDRAKASA 202
                  + L++  R K+S+
Sbjct: 613  TAHGNTVDLNRAARGKSSS 557
>11257
          Length = 1102

 Score =  149 bits (377), Expect = 5e-37,   Method: Compositional matrix adjust.
 Identities = 69/160 (43%), Positives = 102/160 (63%)
 Frame = -2

Query: 48   KEVMVDDRLVTMQIWDTAGQERFQSLGVAFYRGADCCVLVFDVTAPNTFKTLDSWRDEFL 107
            K+V+VD    TMQIWDTAGQER++SL   FYRG DCC+L F V    + ++L  W DEF+
Sbjct: 1053 KDVVVDGETFTMQIWDTAGQERYKSLRTPFYRGTDCCLLTFSVDNLKSLQSLSDWYDEFV 874

Query: 108  IQASPRDPENFPFVVLGNKIDLENRQVATKRAQAWCYSKNNIPYFETSAKEAINVEQAFQ 167
              A  +D  +FPFV++GNK D+E R+V+++ A  WC +  N+PYFETSAK+++NV+QAF 
Sbjct: 873  NYADIQDSASFPFVIIGNKADIEEREVSSEDAYNWCRTHGNLPYFETSAKDSLNVQQAFL 694

Query: 168  TIARNALKQETEVELYNEFPEPIKLDKNDRAKASAESCSC 207
             + R   + + +++       P + D  D  + +    SC
Sbjct: 693  AVVRRLREMDEQMD-----ERPTRTDTVDLKRVAKVKSSC 589
>08428
          Length = 1109

 Score =  137 bits (346), Expect = 2e-33,   Method: Compositional matrix adjust.
 Identities = 74/170 (43%), Positives = 105/170 (61%), Gaps = 1/170 (0%)
 Frame = -3

Query: 9    LKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQIWDTAGQE 68
            +KV +LGDSGVGK+S++ ++V   +    ++TIGA F++K ++VD      QIWDTAGQE
Sbjct: 1068 VKVCLLGDSGVGKSSIVLRFVTGSYRPSQESTIGASFMSKSLVVDGAGYRFQIWDTAGQE 889

Query: 69   RFQSLGVAFYRGADCCVLVFDVTAPNTFKTLDSWRDEFLIQASPRDPENFPFVVLGNKID 128
            +F++L   +YRGA   V+V+DVT P TFK++ SW  E         P N    + GNK D
Sbjct: 888  KFRALAPMYYRGAAAAVIVYDVTRPRTFKSVKSWIQEL----RSFGPPNIVLAIAGNKCD 721

Query: 129  LEN-RQVATKRAQAWCYSKNNIPYFETSAKEAINVEQAFQTIARNALKQE 177
            LE  R+V  K AQ +  S + I + ETSA  A+NVE+ F  +AR    +E
Sbjct: 720  LEELREVVEKDAQEYASSISAI-FGETSAMTAVNVEEMFTELARQLPPEE 574
>05468
          Length = 1558

 Score =  124 bits (311), Expect = 3e-29,   Method: Compositional matrix adjust.
 Identities = 65/182 (35%), Positives = 109/182 (59%), Gaps = 3/182 (1%)
 Frame = -3

Query: 4    RKKVLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVD-DRLVTMQIW 62
            +K+ L K++++G+ G GKTS++ +YV++ FS  Y+ATIG DF  K +  D D L+ +Q+W
Sbjct: 1553 KKEHLYKILVIGELGTGKTSIIKRYVHQFFSQHYRATIGVDFALKVLNWDADTLIRLQLW 1374

Query: 63   DTAGQERFQSLGVAFYRGADCCVLVFDVTAPNTFKTLDSWRDEFLIQASPRDPENFPFVV 122
            D AGQERF ++   +Y+ A    +VFDVT  +TF  +  W+++   +    D    P V+
Sbjct: 1373 DIAGQERFGNMTRVYYKEAVGAFVVFDVTRASTFDAVTKWKNDLDSKVQLADGSPVPCVL 1194

Query: 123  LGNKIDLENRQVATKRAQA--WCYSKNNIPYFETSAKEAINVEQAFQTIARNALKQETEV 180
            L NK D     +    +Q   +C  K  I ++ETSAKE IN+++A + +    L+++  +
Sbjct: 1193 LANKCDQAKEGLVNNTSQMDEFCSEKGFIGWYETSAKENINIDEAARFLVTRILEKDRAM 1014

Query: 181  EL 182
            +L
Sbjct: 1013 QL 1008
>34468
          Length = 1502

 Score =  111 bits (278), Expect = 2e-25,   Method: Compositional matrix adjust.
 Identities = 66/173 (38%), Positives = 101/173 (58%), Gaps = 9/173 (5%)
 Frame = +1

Query: 8   LLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQIWDTAGQ 67
           + K+I++GDS VGKT L  ++   KF ++ +ATIG DF  K + VD   + +Q+WDTAGQ
Sbjct: 493 IFKIIVIGDSNVGKTCLTYRFCLGKFPDKTEATIGVDFREKSIQVDSEHLKLQLWDTAGQ 672

Query: 68  ERF-QSLGVAFYRGADCCVLVFDVTAPNTFKTLDSWRDEFLIQASPRDPENF----PFVV 122
           ERF +S+   +YR     V V+D+T  ++F+ + +W +E        D  N     P ++
Sbjct: 673 ERFRKSMVQHYYRNVHAVVFVYDMTKMSSFENMPAWIEEC-------DRHNLTKYIPRIL 831

Query: 123 LGNKIDLENR-QVATKRAQAWCYSKNNIPYFETSAKE---AINVEQAFQTIAR 171
           +GNK D+  R  V T  AQ +    +N+P FETSAK+   A +V+  F T+A 
Sbjct: 832 VGNKCDVVERIAVNTNLAQKFA-DAHNMPLFETSAKDDEKANHVDAIFMTVAH 987
>26083
          Length = 432

 Score =  100 bits (248), Expect = 6e-22,   Method: Compositional matrix adjust.
 Identities = 43/97 (44%), Positives = 67/97 (69%)
 Frame = +1

Query: 9   LKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQIWDTAGQE 68
            K++ LG+  VGKTSL+ +++   F N Y+ATIG DFL+K + ++DR + +Q+WDTAGQE
Sbjct: 79  FKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTIRLQLWDTAGQE 258

Query: 69  RFQSLGVAFYRGADCCVLVFDVTAPNTFKTLDSWRDE 105
           RF+SL  ++ R +   V+V+D+T  N+F     W D+
Sbjct: 259 RFRSLIPSYIRDSSVAVVVYDITNANSFHQTSKWIDD 369
>07465
          Length = 1103

 Score =  100 bits (248), Expect = 6e-22,   Method: Compositional matrix adjust.
 Identities = 55/170 (32%), Positives = 90/170 (52%), Gaps = 1/170 (0%)
 Frame = +3

Query: 22  TSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQIWDTAGQERFQSLGVAFYRGA 81
           +S++ +Y    F+  YK TIG DFL +++ V    V + +WDTAGQE F ++  A+YRGA
Sbjct: 240 SSMIQRYCKGIFTKDYKKTIGVDFLERQIEVGGEDVRLMLWDTAGQEEFDAITKAYYRGA 419

Query: 82  DCCVLVFDVTAPNTFKTLDSWRDEFLIQASPRDPENFPFVVLGNKIDLENRQVATKRAQA 141
             CVL F     ++F+ L++W+ +   +           V++ NKIDL +  V       
Sbjct: 420 QACVLAFSTVDRDSFEALETWKRKVEDEVGE-----IGMVIVQNKIDLIDDAVVRPEEAE 584

Query: 142 WCYSKNNIPYFETSAKEAINVEQAFQTIARNALKQ-ETEVELYNEFPEPI 190
               K  + ++ TS KE +NV++ F+ +A   L Q  T ++  N  P+ I
Sbjct: 585 NLAKKLRLRFYRTSVKENMNVDEVFRYLADKYLHQLNTGMDEVNLTPQKI 734
>33374
          Length = 489

 Score = 99.4 bits (246), Expect = 9e-22,   Method: Compositional matrix adjust.
 Identities = 54/119 (45%), Positives = 73/119 (61%), Gaps = 1/119 (0%)
 Frame = +1

Query: 45  FLTKEVMVDDRLVTMQIWDTAGQERFQSLGVAFYRGADCCVLVFDVTAPNTFKTLDSWRD 104
           FLT+ V +DD  V  +IWDTAGQER+ SL   +YRGA   ++V+D+T  +TF    +W  
Sbjct: 139 FLTQTVCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNQDTFGRAKTWVK 318

Query: 105 EFLIQASPRDPENFPFVVLGNKIDLEN-RQVATKRAQAWCYSKNNIPYFETSAKEAINV 162
           E   QASP    N    + GNK DL N R V  + AQA+   +N++ + ETSAK A+NV
Sbjct: 319 ELQRQASP----NIVIALAGNKADLANKRMVEFEEAQAYA-EENSLLFMETSAKTAMNV 480

 Score = 38.5 bits (88), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 21/61 (34%), Positives = 38/61 (62%)
 Frame = +2

Query: 9  LKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQIWDTAGQE 68
           K+++LG+S VGK+SL+ ++V  +F    ++TIGA F  ++ +    L+T Q    +G +
Sbjct: 32 FKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAF*LRQFV----LMTQQSSLRSGTQ 199

Query: 69 R 69
          R
Sbjct: 200R 202
>13901
          Length = 962

 Score = 97.1 bits (240), Expect = 4e-21,   Method: Compositional matrix adjust.
 Identities = 45/99 (45%), Positives = 64/99 (64%), Gaps = 1/99 (1%)
 Frame = -3

Query: 5   KKVLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRL-VTMQIWD 63
           ++VL KVII+GD  VGKTS + +YVN  F   YK TIG DF  K +   D+  + +Q+WD
Sbjct: 297 EEVLFKVIIIGDPTVGKTSFVQRYVNDSFRRDYKMTIGVDFALKVIRWSDKCNIKLQLWD 118

Query: 64  TAGQERFQSLGVAFYRGADCCVLVFDVTAPNTFKTLDSW 102
            AGQERF S+   +Y+ A  C+++FD+T  NT++    W
Sbjct: 117 IAGQERFTSMTRVYYKDAHACIVMFDLTQKNTYQNAIRW 1
>01972
          Length = 2359

 Score = 85.5 bits (210), Expect(2) = 1e-20,   Method: Compositional matrix adjust.
 Identities = 50/166 (30%), Positives = 84/166 (50%), Gaps = 2/166 (1%)
 Frame = +3

Query: 30  NKKFSNQYKATIGADFLTKEVMVDDRLVTMQIWDTAGQERFQSLGVAFYRGADCCVLVFD 89
           +++   +Y AT+G +            +   +WDTAGQE+F  L   +Y    C V++FD
Sbjct: 366 HRRI*KKYVATLGVEVHPLLFHTSRGKLKFNVWDTAGQEKFGGLRDGYYIQGQCAVIMFD 545

Query: 90  VTAPNTFKTLDSWRDEFLIQASPRDPENFPFVVLGNKIDLENRQVATKRAQAWCYSKNNI 149
           VT+  T+K + +W  + +     R  EN P V+ GNK+D+++R+V  K      + K N+
Sbjct: 546 VTSRVTYKNVPNWHRDLV-----RVCENIPIVLCGNKVDIKDRKVKAKAIV--FHRKKNL 704

Query: 150 PYFETSAKEAINVEQAFQTIARNALKQETE--VELYNEFPEPIKLD 193
            Y++ SAK   N E+ F  +AR  +       VE+    P  + +D
Sbjct: 705 QYYDISAKSNYNFEKPFLWLARKLVGDPNLEFVEMPALLPPEVAMD 842

 Score = 30.4 bits (67), Expect(2) = 1e-20,   Method: Compositional matrix adjust.
 Identities = 10/25 (40%), Positives = 19/25 (76%)
 Frame = +1

Query: 9   LKVIILGDSGVGKTSLMNQYVNKKF 33
            K++++GD GVGKT+ + ++V  +F
Sbjct: 304 FKLVLVGDGGVGKTTFVKRHVTGEF 378
>07580
          Length = 921

 Score = 74.7 bits (182), Expect(2) = 9e-17,   Method: Compositional matrix adjust.
 Identities = 46/147 (31%), Positives = 75/147 (51%)
 Frame = +3

Query: 33  FSNQYKATIGADFLTKEVMVDDRLVTMQIWDTAGQERFQSLGVAFYRGADCCVLVFDVTA 92
           F  +Y  TI  D   K+V VD +   ++I DTAG E+F ++   + +     +L + +TA
Sbjct: 135 FVEKYDPTI-EDSYRKQVEVDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFLLAYSITA 311

Query: 93  PNTFKTLDSWRDEFLIQASPRDPENFPFVVLGNKIDLENRQVATKRAQAWCYSKNNIPYF 152
            +TF  L   R++ L     +D ++ P +++GNK DLE+ +V  K          +  + 
Sbjct: 312 QSTFNDLQELREQIL---RVKDTDDVPMLLVGNKCDLEDERVVGKDQGQGLARSFSCAFL 482

Query: 153 ETSAKEAINVEQAFQTIARNALKQETE 179
           ETSAK  INV + F  + R   K+  E
Sbjct: 483 ETSAKARINVNEIFMDLVRQINKKSPE 563

 Score = 28.5 bits (62), Expect(2) = 9e-17,   Method: Compositional matrix adjust.
 Identities = 11/27 (40%), Positives = 18/27 (66%)
 Frame = +2

Query: 10 KVIILGDSGVGKTSLMNQYVNKKFSNQ 36
          K+++LG  GVGK++L  Q+V   F  +
Sbjct: 65 KLVVLGSGGVGKSALTVQFVQGDFCGK 145
>33794
          Length = 779

 Score = 81.6 bits (200), Expect = 2e-16,   Method: Compositional matrix adjust.
 Identities = 46/133 (34%), Positives = 77/133 (57%), Gaps = 1/133 (0%)
 Frame = -1

Query: 45  FLTKEVMVDDRLVTMQIWDTAGQERFQSLGVAFYRGADCCVLVFDVTAPNTFKTLDSWRD 104
           + T  ++++ + V +QIWDT+GQ RF ++  ++ RGA   +LV+D+T   +F  +D W  
Sbjct: 686 YKTTTILLEGKRVKLQIWDTSGQGRFCTIIRSYSRGAQGIILVYDITNKWSFDGIDRWLK 507

Query: 105 EFLIQASPRDPENFPFVVLGNKIDLE-NRQVATKRAQAWCYSKNNIPYFETSAKEAINVE 163
           E    A        P V++GN++ L   RQVA K+A+ +  S+NN+  FE S     N+ 
Sbjct: 506 EVEEHA-----PGIPKVLVGNRLHLAYKRQVAAKQAETYA-SRNNMSCFEISPLCDFNIR 345

Query: 164 QAFQTIARNALKQ 176
           ++F  +AR AL +
Sbjct: 344 ESFCELARMALHR 306
>34359
          Length = 1042

 Score = 74.7 bits (182), Expect = 2e-14,   Method: Compositional matrix adjust.
 Identities = 40/132 (30%), Positives = 70/132 (53%), Gaps = 3/132 (2%)
 Frame = +3

Query: 9   LKVIILGDSGVGKTSLMNQYVNKKFSN---QYKATIGADFLTKEVMVDDRLVTMQIWDTA 65
            K++++G    G+    N  V +  +    +Y AT+G +    +      L+   +WDTA
Sbjct: 54  FKLVLVG----GRWEWANNIVKRHVTGS*KKYVATLGVEVHPLQFNTSRGLLRFNVWDTA 221

Query: 66  GQERFQSLGVAFYRGADCCVLVFDVTAPNTFKTLDSWRDEFLIQASPRDPENFPFVVLGN 125
           GQE+F  L   +Y    C +++FDVT+  T+K + +W  + +     R  EN P V+ GN
Sbjct: 222 GQEKFGGLRDGYYIQGTCAIIMFDVTSRVTYKNVPNWHRDLV-----RVCENIPIVLCGN 386

Query: 126 KIDLENRQVATK 137
           K+D+++R+V  K
Sbjct: 387 KVDIKDRKVKAK 422
>30760
          Length = 596

 Score = 72.4 bits (176), Expect = 1e-13,   Method: Compositional matrix adjust.
 Identities = 54/174 (31%), Positives = 84/174 (48%), Gaps = 6/174 (3%)
 Frame = -1

Query: 10  KVIILGDSGVGKTSLMNQYVN--KKFSNQYKATIGADFLTKEVMVDDRL--VTMQIWDTA 65
           K I+ GDSGVGK+S+   + +    F   Y  T G + L K V + D    V + ++D+A
Sbjct: 524 KCIVTGDSGVGKSSICQVFHSDSAHFPKNYSMTTGVEVLVKLVNIPDSRDQVELYLFDSA 345

Query: 66  GQERFQSLGVAFYRGADCCVLVFDVTAPNTFKTLDSWRDEFLIQASPRDPENFPFVVLGN 125
           G+E F      F+      ++V+DVT   +F     W  E +  A P      P V++ N
Sbjct: 344 GKEIFSENVTKFWDQPSVVMVVYDVTDETSFSGCVRWL-ERVRAAKPNTV--IPGVLVAN 174

Query: 126 KIDLENRQVATKRAQAWCYSKNNIPYFETSAKEAINVEQAFQTIAR--NALKQE 177
           K DL+ R+  +++        + + YFE SAKE  N +  F  +A   + L QE
Sbjct: 173 KTDLDERRRVSRKEGKDLAQSHGLEYFECSAKEMQNTDTPFFCLAHAFHKLYQE 12
>11728
          Length = 635

 Score = 72.4 bits (176), Expect = 1e-13,   Method: Compositional matrix adjust.
 Identities = 42/131 (32%), Positives = 70/131 (53%), Gaps = 2/131 (1%)
 Frame = -1

Query: 9   LKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQIWDTAGQE 68
           +K +++GD  VGKT L+  Y    F  +Y  T+  D  +  VMVD + + + +WDTAGQE
Sbjct: 488 IKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTV-FDNYSANVMVDSKPINLGLWDTAGQE 312

Query: 69  RFQSLGVAFYRGADCCVLVFDVTAPNTFKTLDS-WRDEFLIQASPRDPENFPFVVLGNKI 127
            +  L    Y   D  ++ F + +P +F+ + + W  E     S   P N P +++G K+
Sbjct: 311 DYDRLRPLSYPQTDVFLICFSLISPASFENVKAKWYPE----VSHHCP-NTPIILVGTKL 147

Query: 128 DL-ENRQVATK 137
           DL E+++   K
Sbjct: 146 DLREDKETIEK 114
>00858
          Length = 1658

 Score = 71.6 bits (174), Expect = 2e-13,   Method: Compositional matrix adjust.
 Identities = 46/151 (30%), Positives = 75/151 (49%)
 Frame = -2

Query: 21   KTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQIWDTAGQERFQSLGVAFYRG 80
            K++L  Q     F  +Y  T   D   K+V++D     + I DTAGQE   ++     R 
Sbjct: 1552 KSALTIQLXQNHFVEEYDPTX-EDSXRKQVVIDGETCLLDILDTAGQEEXSAMRDQCMRT 1376

Query: 81   ADCCVLVFDVTAPNTFKTLDSWRDEFLIQASPRDPENFPFVVLGNKIDLENRQVATKRAQ 140
             +  + VF V    +F+ ++ +R++       +D +  P V++GNK+DL  R V  ++ +
Sbjct: 1375 GEGFLCVFAVXNLKSFEDINQYREQI---KRVKDADEVPMVLVGNKVDLPIRNVEQRQGK 1205

Query: 141  AWCYSKNNIPYFETSAKEAINVEQAFQTIAR 171
                   +IPY ETSAK    V+ AF T+ R
Sbjct: 1204 HMA-ELYHIPYVETSAKTRQGVDDAFYTLVR 1115
>01398
          Length = 1421

 Score = 70.5 bits (171), Expect = 5e-13,   Method: Compositional matrix adjust.
 Identities = 37/111 (33%), Positives = 64/111 (57%), Gaps = 1/111 (0%)
 Frame = -2

Query: 67   QERFQSLGVAFYRGADCCVLVFDVTAPNTFKTLDSWRDEFLIQASPRDPENFPFVVLGNK 126
            QERF+S+  ++YR +   ++V+D+T  +TF+ L  W +E     +  +P    F+VLG+K
Sbjct: 1420 QERFRSITRSYYRNSVGVIIVYDITKRSTFENLKQWYEE---ARNHIEPHKAIFLVLGHK 1250

Query: 127  IDLEN-RQVATKRAQAWCYSKNNIPYFETSAKEAINVEQAFQTIARNALKQ 176
             D E+ RQV  +  + +    + + +FETSAK   N+E  F  IA++  + 
Sbjct: 1249 SDREDARQVTAREGRRFA-EMHGLKFFETSAKSGHNIEDVFAQIAKDTYQH 1100
>13750
          Length = 503

 Score = 70.1 bits (170), Expect = 5e-13,   Method: Compositional matrix adjust.
 Identities = 53/158 (33%), Positives = 82/158 (51%), Gaps = 8/158 (5%)
 Frame = -2

Query: 21  KTSLMNQYVNKKFSNQYKATIG---ADFLTKEVMVDDRLVTMQIWDTAGQERFQSLGVAF 77
           KT L+ +Y    F ++   TI    ++F   E   D   V   +WDT G E ++SL V+ 
Sbjct: 502 KTCLLRRYQKGFFMDRTMPTIAVLCSEF--NESRTDPLNVRYTLWDTGGAETYRSLWVSH 329

Query: 78  YRGADCCVLVFDVTAPNTFKTLDS-WRDEFLIQASPRDPENFP---FVVLGNKIDL-ENR 132
           +RGA   +LV+DVT   +F T  + WR   +        +N P    + +G+K DL ENR
Sbjct: 328 FRGAQVALLVYDVTCEWSFLTATTVWRKALM--------KNIPEAQVIFVGSKTDLEENR 173

Query: 133 QVATKRAQAWCYSKNNIPYFETSAKEAINVEQAFQTIA 170
            ++T+R QA+  ++    +FETS+    NV+  F  IA
Sbjct: 172 VISTERGQAFA-TQCGYTFFETSSVTGKNVDAVFWEIA 62
>19656
          Length = 428

 Score = 68.6 bits (166), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 36/98 (36%), Positives = 53/98 (54%), Gaps = 1/98 (1%)
 Frame = +3

Query: 9   LKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQIWDTAGQE 68
           +K +++GD  VGKT L+  Y    F  +Y  T+  D  +  VMVD R V + +WDTAGQE
Sbjct: 114 IKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTV-FDNYSANVMVDGRPVNLGLWDTAGQE 290

Query: 69  RFQSLGVAFYRGADCCVLVFDVTAPNTFKTLDS-WRDE 105
            +  L    Y   D  +L F V +P +F+ + + W  E
Sbjct: 291 DYDRLRPLSYPQTDVFLLCFSVASPASFENIRAKWYPE 404
>33380
          Length = 282

 Score = 68.6 bits (166), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 34/85 (40%), Positives = 51/85 (60%)
 Frame = +3

Query: 50  VMVDDRLVTMQIWDTAGQERFQSLGVAFYRGADCCVLVFDVTAPNTFKTLDSWRDEFLIQ 109
           V   D+ V +QIWDTAGQER++++  A+YRGA   +L++DVT   +F  +  W      Q
Sbjct: 39  VFRQDKRVKLQIWDTAGQERYRTITTAYYRGAMGFILMYDVTNEESFNAVQDW----CTQ 206

Query: 110 ASPRDPENFPFVVLGNKIDLENRQV 134
                 +N   V++GNK DLE+ +V
Sbjct: 207 IKTYSWDNAQVVLVGNKCDLEDERV 281
>19006
          Length = 568

 Score = 68.6 bits (166), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 40/130 (30%), Positives = 70/130 (53%), Gaps = 1/130 (0%)
 Frame = -2

Query: 10  KVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQIWDTAGQER 69
           K++I+GD   GKT L+  +   +F   Y  T+  +++  ++ VD + V + +WDTAGQE 
Sbjct: 432 KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVA-DIEVDSKQVELALWDTAGQED 256

Query: 70  FQSLGVAFYRGADCCVLVFDVTAPNTFKTL-DSWRDEFLIQASPRDPENFPFVVLGNKID 128
           +  L    Y   D  ++ F + +P++ + + + W  E +    P    N P +++GNK D
Sbjct: 255 YDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPE-VRHFCP----NVPIILVGNKKD 91

Query: 129 LENRQVATKR 138
           L N +  TKR
Sbjct: 90  LRNDE-NTKR 64
>00552
          Length = 455

 Score = 67.8 bits (164), Expect = 3e-12,   Method: Compositional matrix adjust.
 Identities = 33/56 (58%), Positives = 42/56 (75%)
 Frame = -1

Query: 5   KKVLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQ 60
           K  LLKV++LGD GVGK+SLMN++V+ KF  Q   TIG +FLTK+V+VD    TMQ
Sbjct: 455 KSRLLKVVLLGDGGVGKSSLMNRFVSNKFDAQSFHTIGVEFLTKDVVVDGETFTMQ 288

 Score = 63.2 bits (152), Expect = 7e-11,   Method: Compositional matrix adjust.
 Identities = 26/47 (55%), Positives = 33/47 (70%)
 Frame = -3

Query: 61  IWDTAGQERFQSLGVAFYRGADCCVLVFDVTAPNTFKTLDSWRDEFL 107
           IWDTAGQER++SL   FYRG DCC+L F V    + ++L  W DEF+
Sbjct: 147 IWDTAGQERYKSLRTPFYRGTDCCLLTFSVDNLKSLQSLSDWYDEFV 7
>35581
          Length = 364

 Score = 67.4 bits (163), Expect = 4e-12,   Method: Compositional matrix adjust.
 Identities = 36/105 (34%), Positives = 57/105 (54%), Gaps = 1/105 (0%)
 Frame = +2

Query: 2   TSRKKVLLKVIILGDSGVGKTSLMNQYVNKKFSNQ-YKATIGADFLTKEVMVDDRLVTMQ 60
           T    +  K ++LGD+GVGKT L+N+    KF +    +   A  LT   +    + ++ 
Sbjct: 26  TGNDTLYFKCVLLGDAGVGKTCLLNRLATDKFLDSPLTSLTTASLLTTVTLTSGVMASVD 205

Query: 61  IWDTAGQERFQSLGVAFYRGADCCVLVFDVTAPNTFKTLDSWRDE 105
           +WDTAGQER++SL  ++YR     ++V+D  A +  K  D W D 
Sbjct: 206 LWDTAGQERYRSLTSSYYRDTKAVLIVYD--AEHKLKLTD-WTDR 331
>32723
          Length = 384

 Score = 65.9 bits (159), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 39/105 (37%), Positives = 63/105 (60%), Gaps = 1/105 (0%)
 Frame = +2

Query: 67  QERFQSLGVAFYRGADCCVLVFDVTAPNTFKTLDSWRDEFLIQASPRDPENFPFVVLGNK 126
           QERF+S+  ++YR A+  +LV+DV +  ++++L  W  E  + A  +      F+V GNK
Sbjct: 2   QERFRSITQSYYRSANALILVYDVCSQQSYESLPQWIHEIELYAGTK---VLAFLV-GNK 169

Query: 127 ID-LENRQVATKRAQAWCYSKNNIPYFETSAKEAINVEQAFQTIA 170
           ID  + R++ T   + +   +  + + ETSAKEA NVE+ F TIA
Sbjct: 170 IDQTDKREIPTHIGKEFA-ERYEMRFLETSAKEADNVEKLFSTIA 301
>27191
          Length = 443

 Score = 59.3 bits (142), Expect(2) = 5e-10,   Method: Compositional matrix adjust.
 Identities = 32/109 (29%), Positives = 55/109 (50%), Gaps = 2/109 (1%)
 Frame = +1

Query: 21  KTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQIWDTAGQERFQSLGVAFYRG 80
           KT L+  +   KF+  Y+ T+G D+  K   V+   + + +WD +G   +  +    Y G
Sbjct: 1   KTCLIKHFCESKFNQGYQPTVGVDYGFKIQTVNGVDMRVHMWDLSGSNEYLDVRNELYTG 180

Query: 81  ADCCVLVFDVTAPNTFKTLDSWRDEF--LIQASPRDPENFPFVVLGNKI 127
           +D   +VFDV+   +F+ LDSW  E       SP +      V++GN++
Sbjct: 181 SDAIFIVFDVSNTPSFEALDSWLREINRFATGSPLN------VIVGNRV 309

 Score = 21.2 bits (43), Expect(2) = 5e-10,   Method: Compositional matrix adjust.
 Identities = 9/24 (37%), Positives = 12/24 (50%)
 Frame = +2

Query: 146 KNNIPYFETSAKEAINVEQAFQTI 169
            N   Y+ETSA     V+  FQ +
Sbjct: 362 HNKCLYYETSAATGEGVDDMFQQM 433
>26536
          Length = 829

 Score = 59.7 bits (143), Expect = 7e-10,   Method: Compositional matrix adjust.
 Identities = 40/140 (28%), Positives = 67/140 (47%), Gaps = 3/140 (2%)
 Frame = +2

Query: 46  LTKEVMVDDRLVTMQIWDTAGQERFQSLGVAFYRGADCCVLVFDVTAPNTFKTLDS---W 102
           LT   M+ +R V+    DTAGQE + S+   + R  D  ++V+ VT   +F+  ++   W
Sbjct: 95  LTTMKMMMERRVSWTFLDTAGQEEYSSMREHYTRSGDGFIVVYSVTDVTSFQEAEAVFRW 274

Query: 103 RDEFLIQASPRDPENFPFVVLGNKIDLENRQVATKRAQAWCYSKNNIPYFETSAKEAINV 162
              F      +D  +   V+ GNK DL + +  T         +  + YFETSAK   NV
Sbjct: 275 LTRF------QDETSIHAVLCGNKTDLTSDRKVTPEEGRKMADRLGMLYFETSAKTGDNV 436

Query: 163 EQAFQTIARNALKQETEVEL 182
            Q +  + R+  +  T+ ++
Sbjct: 437 SQVYHGLLRSIPRSGTDYKI 496
>01095
          Length = 1745

 Score = 56.2 bits (134), Expect = 9e-09,   Method: Compositional matrix adjust.
 Identities = 37/93 (39%), Positives = 51/93 (54%), Gaps = 1/93 (1%)
 Frame = -1

Query: 86   LVFDVTAPNTFKTLDSWRDEFLIQASPRDPENFPFVVLGNKIDLEN-RQVATKRAQAWCY 144
            +V+D+T  +TF    +W  E   QASP    N    + GNK DL N R V  + AQA+  
Sbjct: 1745 VVYDITNQDTFGRAKTWVKELQRQASP----NIVIALAGNKADLANKRMVEFEEAQAYA- 1581

Query: 145  SKNNIPYFETSAKEAINVEQAFQTIARNALKQE 177
             +N++ + ETSAK A+NV   F  IA+   K E
Sbjct: 1580 EENSLLFMETSAKTAMNVNDIFLAIAKKLPKNE 1482
>19046
          Length = 445

 Score = 55.5 bits (132), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 31/106 (29%), Positives = 59/106 (55%), Gaps = 1/106 (0%)
 Frame = -2

Query: 67  QERFQSLGVAFYRGADCCVLVFDVTAPNTFKTLDSWRDEFLIQASPRDPENFPFVVLGNK 126
           QE F ++   + R  D  +LVF VT   +F+ + ++  + L     +D +++P ++  NK
Sbjct: 444 QEEFSAMREQYMRKGDGFLLVFSVTDFRSFENMANFHTQIL---RVKDRDSYPMILCANK 274

Query: 127 IDLENRQVATKRAQAWCYSKNNIPYFETSAKE-AINVEQAFQTIAR 171
           +DL +++  ++       ++  IPY ETSAK+  +NV+ AF  + R
Sbjct: 273 VDLVHQRKVSEEQVRDLATRLRIPYIETSAKDPPLNVDLAFHQVVR 136
>24619
          Length = 509

 Score = 53.5 bits (127), Expect = 7e-08,   Method: Compositional matrix adjust.
 Identities = 30/106 (28%), Positives = 57/106 (53%), Gaps = 1/106 (0%)
 Frame = -2

Query: 67  QERFQSLGVAFYRGADCCVLVFDVTAPNTFKTLDSWRDEFLIQASPRDPENFPFVVLGNK 126
           QE F ++   + R  D  +LVF V    +F+ + ++  + L     +D + +P ++  NK
Sbjct: 508 QEEFSAMREQYMRKGDGFLLVFSVIDYQSFENMVNFHTQIL---RVKDRDTYPMILCANK 338

Query: 127 IDLENRQVATKRAQAWCYSKNNIPYFETSAKE-AINVEQAFQTIAR 171
           +DL +++  ++       ++  IPY ETSAK+  +NV+ AF  + R
Sbjct: 337 VDLVHQRKVSEEQVRDLATRLRIPYIETSAKDPPLNVDLAFHQVVR 200
>31291
          Length = 446

 Score = 51.2 bits (121), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 41/145 (28%), Positives = 66/145 (45%), Gaps = 14/145 (9%)
 Frame = -1

Query: 59  MQIWDTAGQERFQSLGVAFYRGADCCVLVFDVTAPNTFKTLD-SWRDEFLIQASPRDPEN 117
           +Q+WDTAGQE +  L    Y   D  +L F + +  + K +   W  E        DP +
Sbjct: 446 LQLWDTAGQEDYDRLRPLAYPNTDVFMLXFSLMSEASMKNVKVKWYPEIRHH----DP-H 282

Query: 118 FPFVVLGNKIDLEN-----RQVATKRAQAWCYSKNN--------IPYFETSAKEAINVEQ 164
            P V++G K+DL       R++ + R      ++ N          YFE S+K   N++ 
Sbjct: 281 VPIVLVGTKLDLRQDKEAVRKLRSSRQDPVSSNQGNDLAKAIKAKRYFECSSKTQENLKT 102

Query: 165 AFQTIARNALKQETEVELYNEFPEP 189
           AF+   R AL  + +    N+ P+P
Sbjct: 101 AFEETVRVALNMDGQ---NNKRPKP 36
>29380
          Length = 853

 Score = 50.1 bits (118), Expect = 6e-07,   Method: Compositional matrix adjust.
 Identities = 29/101 (28%), Positives = 55/101 (54%), Gaps = 2/101 (1%)
 Frame = -2

Query: 81  ADCCVLVFDVTAPNTFKTLDSWRDEFLIQASPRDPENFPFVVLGNKIDL--ENRQVATKR 138
           A   ++V+DV   +TF    +W  E       ++ E+   ++ GNK+DL  ++R V+ + 
Sbjct: 852 ASAAIIVYDVNIADTFSRALAWVKEL----RQQNTESVLIILAGNKVDLATQHRAVSFED 685

Query: 139 AQAWCYSKNNIPYFETSAKEAINVEQAFQTIARNALKQETE 179
           AQ++   +N + + E SAK  + V + F T+A   ++QE +
Sbjct: 684 AQSFA-RENGLLFAEVSAKTGMAVNEIFMTLANQLIQQEID 565
>10708
          Length = 2775

 Score = 36.2 bits (82), Expect(2) = 1e-06,   Method: Compositional matrix adjust.
 Identities = 19/59 (32%), Positives = 30/59 (50%), Gaps = 4/59 (6%)
 Frame = -2

Query: 57   VTMQIWDTAGQERFQSLGVAFYRGADCCVLVFDVTAPNTFKTL----DSWRDEFLIQAS 111
            V + +WDTAGQE +  L    Y   D  ++ F + +P++ + +    DS    FL Q S
Sbjct: 2723 VELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKVDSRGAPFLSQCS 2547

 Score = 32.3 bits (72), Expect(2) = 1e-06,   Method: Compositional matrix adjust.
 Identities = 24/73 (32%), Positives = 32/73 (43%), Gaps = 14/73 (19%)
 Frame = -3

Query: 117  NFPFVVLGNKIDLENRQVATKR--------------AQAWCYSKNNIPYFETSAKEAINV 162
            N P +++GNK DL N +  TKR               +A     N   Y E SAK    V
Sbjct: 2554 NVPIILVGNKKDLRNDE-NTKRELMKMKQEPVRLDEGRAMSEKINAYSYLECSAKTKEGV 2378

Query: 163  EQAFQTIARNALK 175
             + F+T  R AL+
Sbjct: 2377 REVFETATRAALQ 2339
>34597
          Length = 773

 Score = 47.0 bits (110), Expect = 6e-06,   Method: Compositional matrix adjust.
 Identities = 28/85 (32%), Positives = 49/85 (57%)
 Frame = -2

Query: 116 ENFPFVVLGNKIDLENRQVATKRAQAWCYSKNNIPYFETSAKEAINVEQAFQTIARNALK 175
           E+   ++LGNK D+ +++V +K        +++I + ETSAK  IN+E+AF  +A  A+ 
Sbjct: 658 EDVEKMILGNKCDMTDKRVVSKERGEAIAREHSIRFMETSAKSNINIERAFCELAE-AIL 482

Query: 176 QETEVELYNEFPEPIKLDKNDRAKA 200
            +T      E PE + +D+ +  KA
Sbjct: 481 DKTAGRESAENPERVVIDRGNSDKA 407
>18509
          Length = 625

 Score = 45.8 bits (107), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 24/63 (38%), Positives = 35/63 (55%)
 Frame = -3

Query: 113 RDPENFPFVVLGNKIDLENRQVATKRAQAWCYSKNNIPYFETSAKEAINVEQAFQTIARN 172
           +D +  P V++GNK+DL  R V  ++ +       +IPY ETSAK    V+ AF T+ R 
Sbjct: 542 KDADEVPMVLVGNKVDLPIRNVEQRQGKHMA-ELYHIPYVETSAKTRQGVDDAFYTLVRE 366

Query: 173 ALK 175
             K
Sbjct: 365 IRK 357
>09204
          Length = 1051

 Score = 45.1 bits (105), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 32/116 (27%), Positives = 54/116 (46%), Gaps = 8/116 (6%)
 Frame = -3

Query: 69   RFQSLGVAFYRGADCCVLVFDVTAPNTFKTLDSWRDEFLIQASPRDPENFPFVVLGNKID 128
            R++++   +YRGA   +L FD+T  ++F  +  W  E       +  E     + G K D
Sbjct: 1049 RYEAMSRIYYRGAKAAILCFDLTDKSSFDRIRFWIGEL-----RQHEEECKLYICGTKFD 885

Query: 129  L-----ENRQVATKRAQAW---CYSKNNIPYFETSAKEAINVEQAFQTIARNALKQ 176
            L     E R V    A+A    C ++     +ETS+    N+E+ F  IA + +K+
Sbjct: 884  LVHDDPERRAVPRSVAKALADDCMAE----IYETSSMTGDNIEKLFTKIAEDYMKE 729
>14775
          Length = 380

 Score = 43.5 bits (101), Expect = 6e-05,   Method: Compositional matrix adjust.
 Identities = 27/74 (36%), Positives = 40/74 (54%), Gaps = 3/74 (4%)
 Frame = -2

Query: 21  KTSLMNQYVNKKFSNQYKATIG---ADFLTKEVMVDDRLVTMQIWDTAGQERFQSLGVAF 77
           KT L+ +Y    F ++   TI    ++F   E   D   V   +WDT G E ++SL V+ 
Sbjct: 379 KTCLLRRYQKGFFMDRTMPTIAVLCSEF--NESRTDPLNVRYTLWDTGGAETYRSLWVSH 206

Query: 78  YRGADCCVLVFDVT 91
           +RGA   +LV+DVT
Sbjct: 205 FRGAQVALLVYDVT 164
>31932
          Length = 437

 Score = 40.8 bits (94), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 22/94 (23%), Positives = 43/94 (45%), Gaps = 5/94 (5%)
 Frame = -1

Query: 119 PFVVLGNKIDLENRQVATKRAQAWCYSKNNIPYFETSAKEAINVEQAFQTIARNALKQET 178
           P ++LGNK DL +R+V     +  C   + + + ETS K+   ++++   +    + +  
Sbjct: 398 PCLLLGNKSDLGHREVEQDEIEDLCKEHDFLGWSETSVKDGTMIDESMNYLIEEMMAKHA 219

Query: 179 EVELYNEFPEPI-----KLDKNDRAKASAESCSC 207
           E+E ++E          +L + D    S   C C
Sbjct: 218 ELEGFSESVTQGNGVIRRLSREDSDVPSGSRCGC 117
>25618
          Length = 475

 Score = 38.9 bits (89), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 26/90 (28%), Positives = 44/90 (48%), Gaps = 2/90 (2%)
 Frame = +3

Query: 120 FVVLGNKIDL--ENRQVATKRAQAWCYSKNNIPYFETSAKEAINVEQAFQTIARNALKQE 177
            V+ GNK DL  E+R V+   A+ +    N + + E SAK  + V + F TIA   +++ 
Sbjct: 84  IVLAGNKADLASEHRAVSADDARTFA-EDNGLIFAEVSAKTGMAVSEVFMTIAHKLVRRA 260

Query: 178 TEVELYNEFPEPIKLDKNDRAKASAESCSC 207
            E +   +  E ++L + + A      C C
Sbjct: 261 EEGQGSXQGRERVRLSEAEEASG---GCKC 341
>05634
          Length = 2200

 Score = 37.4 bits (85), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 18/32 (56%), Positives = 25/32 (78%)
 Frame = +3

Query: 176 QETEVELYNEFPEPIKLDKNDRAKASAESCSC 207
           QE++VELYNEFP+PI++  ND+ K   E C+C
Sbjct: 3   QESDVELYNEFPDPIRV-SNDQNKPK-EGCAC 92
>29461
          Length = 456

 Score = 36.2 bits (82), Expect = 0.010,   Method: Compositional matrix adjust.
 Identities = 26/94 (27%), Positives = 44/94 (46%), Gaps = 3/94 (3%)
 Frame = +3

Query: 73  LGVAFYRG---ADCCVLVFDVTAPNTFKTLDSWRDEFLIQASPRDPENFPFVVLGNKIDL 129
           LG++F R      C + V D++    +  L+  R E L Q  P      P  ++GNKID+
Sbjct: 3   LGISFLRHIQRCXCLLYVLDLSGEAPWLQLEELRFE-LEQYEP-GLSTRPHAIIGNKIDV 176

Query: 130 ENRQVATKRAQAWCYSKNNIPYFETSAKEAINVE 163
           E  Q      Q    ++ ++P +  SAK  + ++
Sbjct: 177 EGAQEMLCELQ----TRIDLPVYAISAKHRLGID 266
>14119
          Length = 602

 Score = 33.9 bits (76), Expect = 0.045,   Method: Compositional matrix adjust.
 Identities = 26/87 (29%), Positives = 41/87 (47%), Gaps = 2/87 (2%)
 Frame = +1

Query: 95  TFKTLDSWRDEFLIQASPRDPENFPFVVLGNKIDL--ENRQVATKRAQAWCYSKNNIPYF 152
           TF    +W  E   Q    +  +   V+ GNK DL  E+R V+   A+ +    N + + 
Sbjct: 1   TFNRALAWVKELRQQ----NAGSVLIVLAGNKADLASEHRAVSADDARTFA-EDNGLIFA 165

Query: 153 ETSAKEAINVEQAFQTIARNALKQETE 179
           E SAK  + V + F TIA   +++  E
Sbjct: 166 EVSAKTGMAVSEVFMTIAHKLVRRAEE 246
>33605
          Length = 888

 Score = 32.7 bits (73), Expect = 0.099,   Method: Compositional matrix adjust.
 Identities = 20/81 (24%), Positives = 40/81 (49%)
 Frame = +1

Query: 9   LKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQIWDTAGQE 68
           +++++LG    GKT+++ ++ N +  +    T+G +  T E     R   + +WD  GQ+
Sbjct: 499 VRLLMLGLDNAGKTTILKKF-NGEDIDTISPTLGFNIKTLE----HRGFKLNVWDVGGQQ 663

Query: 69  RFQSLGVAFYRGADCCVLVFD 89
             +S    ++   D  V V D
Sbjct: 664 SLRSYWRNYFESTDGLVWVVD 726
>08153
          Length = 1703

 Score = 32.7 bits (73), Expect = 0.10,   Method: Compositional matrix adjust.
 Identities = 26/129 (20%), Positives = 60/129 (46%)
 Frame = +1

Query: 9   LKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQIWDTAGQE 68
           ++++++G    GKT+++ +    +       TIG +  T    V+ + ++  +WD  GQ+
Sbjct: 85  VRILMVGLDAAGKTTILYKLKLGEIVTTI-PTIGFNVET----VEYKNISFTVWDVGGQD 249

Query: 69  RFQSLGVAFYRGADCCVLVFDVTAPNTFKTLDSWRDEFLIQASPRDPENFPFVVLGNKID 128
           + + L   +++     + V D    N  + ++  ++E     +  D  +   +V  NK D
Sbjct: 250 KIRPLWRHYFQNTQGLIFVVD---SNDRERINEAKEELARMLNEDDLRDAIILVFANKQD 420

Query: 129 LENRQVATK 137
           L N   A++
Sbjct: 421 LPNAYSASE 447
>10862
          Length = 2896

 Score = 30.0 bits (66), Expect = 0.61,   Method: Compositional matrix adjust.
 Identities = 17/69 (24%), Positives = 30/69 (43%)
 Frame = -3

Query: 61   IWDTAGQERFQSLGVAFYRGADCCVLVFDVTAPNTFKTLDSWRDEFLIQASPRDPENFPF 120
            +WD  GQ++ + L   +Y G    + V D    +    +D  R E     + R+  +   
Sbjct: 2474 VWDVGGQDKIRPLWRHYYTGTQGLIFVVDCADRD---RIDEARQELHRIINDREMRDAII 2304

Query: 121  VVLGNKIDL 129
            ++  NK DL
Sbjct: 2303 LIFANKQDL 2277
>09827
          Length = 1201

 Score = 30.0 bits (66), Expect = 0.66,   Method: Compositional matrix adjust.
 Identities = 24/123 (19%), Positives = 56/123 (45%)
 Frame = -3

Query: 9    LKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQIWDTAGQE 68
            ++++++G    GKT+++ +    +       TIG +  T    V+ + ++  +WD  GQ+
Sbjct: 1112 MRILMVGLDAAGKTTILYKLKLGEIVTTI-PTIGFNVET----VEYKNISFTVWDVGGQD 948

Query: 69   RFQSLGVAFYRGADCCVLVFDVTAPNTFKTLDSWRDEFLIQASPRDPENFPFVVLGNKID 128
            + + L   +++     + V D    N  + +   R+E     +  +  +   +V  NK D
Sbjct: 947  KIRPLWRHYFQNTQGLIFVVD---SNDKERVQEAREELTRMLNEDELRDAVLLVFANKQD 777

Query: 129  LEN 131
            L +
Sbjct: 776  LPH 768
>11378
          Length = 1688

 Score = 29.3 bits (64), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 30/120 (25%), Positives = 53/120 (44%), Gaps = 1/120 (0%)
 Frame = +3

Query: 10  KVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEV-MVDDRLVTMQIWDTAGQE 68
           K++ LG    GKT+L++   + K + Q+  T+     ++E+ M   R  T   +D  G  
Sbjct: 327 KLVFLGLDNAGKTTLLHMLKDDKMA-QHVPTLHPT--SEELSMGGMRFTT---FDLGGHR 488

Query: 69  RFQSLGVAFYRGADCCVLVFDVTAPNTFKTLDSWRDEFLIQASPRDPENFPFVVLGNKID 128
           + + +   ++   D  V + DV          +  D  +   +     N P +VLGNKID
Sbjct: 489 QARRVWKDYFPAVDGIVFLVDVHDRERLVEAKAELDSLM---TDEQVANAPILVLGNKID 659
>06994
          Length = 429

 Score = 27.7 bits (60), Expect = 3.0,   Method: Compositional matrix adjust.
 Identities = 11/24 (45%), Positives = 17/24 (70%)
 Frame = +3

Query: 10 KVIILGDSGVGKTSLMNQYVNKKF 33
          K+++LG  GVGK++L  Q+V   F
Sbjct: 60 KLVVLGSGGVGKSALTVQFVQGIF 131
>14677
          Length = 378

 Score = 27.3 bits (59), Expect = 3.9,   Method: Compositional matrix adjust.
 Identities = 9/21 (42%), Positives = 16/21 (76%)
 Frame = -3

Query: 13  ILGDSGVGKTSLMNQYVNKKF 33
           +LG++G+GK++LM+   N  F
Sbjct: 325 VLGETGIGKSTLMDTLFNTNF 263
>28453
          Length = 979

 Score = 26.9 bits (58), Expect = 6.6,   Method: Compositional matrix adjust.
 Identities = 10/24 (41%), Positives = 15/24 (62%)
 Frame = +1

Query: 20  GKTSLMNQYVNKKFSNQYKATIGA 43
           G TSL+N Y+N+ + N + A  G 
Sbjct: 424 GHTSLLNNYMNEIYHNSFSAINGC 495
>14989
          Length = 896

 Score = 26.2 bits (56), Expect = 9.8,   Method: Compositional matrix adjust.
 Identities = 14/43 (32%), Positives = 21/43 (48%), Gaps = 5/43 (11%)
 Frame = -2

Query: 84  CVLVFDVTAPNTFKTLDSWRDEFLIQASPR-----DPENFPFV 121
           C+ +   TAP +F  L  WR+E  ++  P+     D  NF  V
Sbjct: 505 CLSLPAWTAPRSFGALSLWREESSLRMCPKSRXFLDQSNFSMV 377
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31543565|ref|NP_033025.2| RAB23, member RAS oncogene
family [Mus musculus]
         (237 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

07465                                                                 263   5e-71
17511                                                                 111   2e-25
34468                                                                 108   2e-24
05468                                                                 106   8e-24
08428                                                                 102   1e-22
14456                                                                 100   5e-22
33374                                                                  82   7e-22
07580                                                                  92   2e-21
13901                                                                  96   1e-20
26083                                                                  93   9e-20
01972                                                                  75   2e-18
11728                                                                  79   2e-15
33794                                                                  78   3e-15
19006                                                                  75   2e-14
11257                                                                  75   3e-14
13750                                                                  73   1e-13
19656                                                                  70   8e-13
34359                                                                  69   2e-12
27191                                                                  67   5e-12
26536                                                                  66   1e-11
33380                                                                  66   1e-11
32723                                                                  65   2e-11
13745                                                                  65   2e-11
12339                                                                  65   3e-11
00858                                                                  60   7e-10
19046                                                                  60   9e-10
24619                                                                  58   4e-09
36482                                                                  57   5e-09
01398                                                                  55   2e-08
34597                                                                  51   4e-07
09204                                                                  50   6e-07
00552                                                                  50   9e-07
35581                                                                  48   4e-06
14775                                                                  47   6e-06
31291                                                                  47   8e-06
10708                                                                  39   0.002
08153                                                                  37   0.008
10862                                                                  37   0.009
09827                                                                  35   0.026
00822                                                                  32   0.31 
06994                                                                  31   0.35 
17872                                                                  30   0.78 
33605                                                                  29   1.9  
30174                                                                  28   4.1  
>07465
          Length = 1103

 Score =  263 bits (671), Expect = 5e-71,   Method: Compositional matrix adjust.
 Identities = 130/216 (60%), Positives = 163/216 (75%), Gaps = 2/216 (0%)
 Frame = +3

Query: 23  SSMIQRYCKGIFTKDYKKTIGVDFLERQIQVNDEDVRLMLWDTAGQEEFDAITKAYYRGA 82
           SSMIQRYCKGIFTKDYKKTIGVDFLERQI+V  EDVRLMLWDTAGQEEFDAITKAYYRGA
Sbjct: 240 SSMIQRYCKGIFTKDYKKTIGVDFLERQIEVGGEDVRLMLWDTAGQEEFDAITKAYYRGA 419

Query: 83  QACVLVFSTTDRESFEAISSWREKVVAEVGDIPTALVQNKIDLLDDSCIKNEEAEGLAKR 142
           QACVL FST DR+SFEA+ +W+ KV  EVG+I   +VQNKIDL+DD+ ++ EEAE LAK+
Sbjct: 420 QACVLAFSTVDRDSFEALETWKRKVEDEVGEIGMVIVQNKIDLIDDAVVRPEEAENLAKK 599

Query: 143 LKLRFYRTSVKEDLNVSEVFKYLAEKHLQKLKQQITEDPEQTHSSSNKI--GVFNASVRS 200
           L+LRFYRTSVKE++NV EVF+YLA+K+L +L   + E     + +  KI  G+     ++
Sbjct: 600 LRLRFYRTSVKENMNVDEVFRYLADKYLHQLNTGMDE----VNLTPQKIGQGLIQTETKN 767

Query: 201 HLGQNSSSLNGGDVINLRPNKQRTKRTRNPFSSCSV 236
           H+   S        I+L+P+K+RT   ++  +S  V
Sbjct: 768 HIKDRSGKHRHEGTISLQPSKRRTHGKKSLLTSKCV 875
>17511
          Length = 483

 Score =  111 bits (278), Expect = 2e-25,   Method: Compositional matrix adjust.
 Identities = 49/124 (39%), Positives = 80/124 (64%), Gaps = 5/124 (4%)
 Frame = -3

Query: 7   EVAIKMVVVGNGAVGKSSMIQRYCKGIFTKDYKKTIGVDFLERQIQVNDEDVRLMLWDTA 66
           +V +K++++G+  VGK+S++ +Y    F+  YK TIG DFL +++ V+D  V + +WDTA
Sbjct: 373 KVLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQIWDTA 194

Query: 67  GQEEFDAITKAYYRGAQACVLVFSTTDRESFEAISSWREKVVAEVG-----DIPTALVQN 121
           GQE F ++  A+YRGA  CVLVF  T   +F ++ SWR++ + +       + P  ++ N
Sbjct: 193 GQERFQSLGVAFYRGADCCVLVFDVTMPNTFRSLDSWRDEFLIQASPRDPENFPFVVIGN 14

Query: 122 KIDL 125
           KIDL
Sbjct: 13  KIDL 2
>34468
          Length = 1502

 Score =  108 bits (270), Expect = 2e-24,   Method: Compositional matrix adjust.
 Identities = 60/165 (36%), Positives = 90/165 (54%), Gaps = 6/165 (3%)
 Frame = +1

Query: 10  IKMVVVGNGAVGKSSMIQRYCKGIFTKDYKKTIGVDFLERQIQVNDEDVRLMLWDTAGQE 69
            K++V+G+  VGK+ +  R+C G F    + TIGVDF E+ IQV+ E ++L LWDTAGQE
Sbjct: 496 FKIIVIGDSNVGKTCLTYRFCLGKFPDKTEATIGVDFREKSIQVDSEHLKLQLWDTAGQE 675

Query: 70  EF-DAITKAYYRGAQACVLVFSTTDRESFEAISSWREKVVAE--VGDIPTALVQNKIDLL 126
            F  ++ + YYR   A V V+  T   SFE + +W E+         IP  LV NK D++
Sbjct: 676 RFRKSMVQHYYRNVHAVVFVYDMTKMSSFENMPAWIEECDRHNLTKYIPRILVGNKCDVV 855

Query: 127 DDSCIKNEEAEGLAKRLKLRFYRTSVKEDL---NVSEVFKYLAEK 168
           +   +    A+  A    +  + TS K+D    +V  +F  +A K
Sbjct: 856 ERIAVNTNLAQKFADAHNMPLFETSAKDDEKANHVDAIFMTVAHK 990
>05468
          Length = 1558

 Score =  106 bits (264), Expect = 8e-24,   Method: Compositional matrix adjust.
 Identities = 58/177 (32%), Positives = 100/177 (56%), Gaps = 8/177 (4%)
 Frame = -3

Query: 4    EDMEVAIKMVVVGNGAVGKSSMIQRYCKGIFTKDYKKTIGVDFLERQIQVN-DEDVRLML 62
            E  E   K++V+G    GK+S+I+RY    F++ Y+ TIGVDF  + +  + D  +RL L
Sbjct: 1556 EKKEHLYKILVIGELGTGKTSIIKRYVHQFFSQHYRATIGVDFALKVLNWDADTLIRLQL 1377

Query: 63   WDTAGQEEFDAITKAYYRGAQACVLVFSTTDRESFEAISSWREKV-----VAEVGDIPTA 117
            WD AGQE F  +T+ YY+ A    +VF  T   +F+A++ W+  +     +A+   +P  
Sbjct: 1376 WDIAGQERFGNMTRVYYKEAVGAFVVFDVTRASTFDAVTKWKNDLDSKVQLADGSPVPCV 1197

Query: 118  LVQNKIDLLDDSCIKN--EEAEGLAKRLKLRFYRTSVKEDLNVSEVFKYLAEKHLQK 172
            L+ NK D   +  + N  +  E  +++  + +Y TS KE++N+ E  ++L  + L+K
Sbjct: 1196 LLANKCDQAKEGLVNNTSQMDEFCSEKGFIGWYETSAKENINIDEAARFLVTRILEK 1026
>08428
          Length = 1109

 Score =  102 bits (254), Expect = 1e-22,   Method: Compositional matrix adjust.
 Identities = 53/160 (33%), Positives = 91/160 (56%), Gaps = 1/160 (0%)
 Frame = -3

Query: 10   IKMVVVGNGAVGKSSMIQRYCKGIFTKDYKKTIGVDFLERQIQVNDEDVRLMLWDTAGQE 69
            +K+ ++G+  VGKSS++ R+  G +    + TIG  F+ + + V+    R  +WDTAGQE
Sbjct: 1068 VKVCLLGDSGVGKSSIVLRFVTGSYRPSQESTIGASFMSKSLVVDGAGYRFQIWDTAGQE 889

Query: 70   EFDAITKAYYRGAQACVLVFSTTDRESFEAISSWREKVVA-EVGDIPTALVQNKIDLLDD 128
            +F A+   YYRGA A V+V+  T   +F+++ SW +++ +    +I  A+  NK DL + 
Sbjct: 888  KFRALAPMYYRGAAAAVIVYDVTRPRTFKSVKSWIQELRSFGPPNIVLAIAGNKCDLEEL 709

Query: 129  SCIKNEEAEGLAKRLKLRFYRTSVKEDLNVSEVFKYLAEK 168
              +  ++A+  A  +   F  TS    +NV E+F  LA +
Sbjct: 708  REVVEKDAQEYASSISAIFGETSAMTAVNVEEMFTELARQ 589
>14456
          Length = 1867

 Score =  100 bits (249), Expect = 5e-22,   Method: Compositional matrix adjust.
 Identities = 66/196 (33%), Positives = 106/196 (54%), Gaps = 6/196 (3%)
 Frame = -1

Query: 18   GAVGKSSMIQRYCKGIFTKDYKKTIGVDFLERQIQVNDEDVRLMLWDTAGQEEFDAITKA 77
            G VGKSS++ R+    F      TIGV+FL + + V+DE   + +WDTAGQE F ++   
Sbjct: 1114 GGVGKSSLMNRFVSNKFDAQSFHTIGVEFLNKDVVVDDETYTMQIWDTAGQERFKSLRTP 935

Query: 78   YYRGAQACVLVFSTTDRESFEAISSWREKVV--AEVGD---IPTALVQNKIDLLDDSCIK 132
            +YRGA  C+L FS    +SF  +S WR++ +  A++ D    P  ++ NKID ++   + 
Sbjct: 934  FYRGADCCLLTFSVDSMQSFRNLSMWRKEFLYYADIQDGVTFPFVVLGNKID-VEGRQVT 758

Query: 133  NEEAEGLA-KRLKLRFYRTSVKEDLNVSEVFKYLAEKHLQKLKQQITEDPEQTHSSSNKI 191
            NEEA           ++ TS K+  NV + F  LA   +Q+L++   ED ++  ++    
Sbjct: 757  NEEARSWCTANSNAPYFETSAKDATNVEKAF--LAA--VQRLRE--VEDQQEVKTAHGNT 596

Query: 192  GVFNASVRSHLGQNSS 207
               N + R   G++SS
Sbjct: 595  VDLNRAAR---GKSSS 557
>33374
          Length = 489

 Score = 81.6 bits (200), Expect(2) = 7e-22,   Method: Compositional matrix adjust.
 Identities = 40/117 (34%), Positives = 71/117 (60%), Gaps = 1/117 (0%)
 Frame = +1

Query: 46  FLERQIQVNDEDVRLMLWDTAGQEEFDAITKAYYRGAQACVLVFSTTDRESFEAISSWRE 105
           FL + + ++D  V+  +WDTAGQE + ++   YYRGAQA ++V+  T++++F    +W +
Sbjct: 139 FLTQTVCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNQDTFGRAKTWVK 318

Query: 106 KVVAEVG-DIPTALVQNKIDLLDDSCIKNEEAEGLAKRLKLRFYRTSVKEDLNVSEV 161
           ++  +   +I  AL  NK DL +   ++ EEA+  A+   L F  TS K  +NV+++
Sbjct: 319 ELQRQASPNIVIALAGNKADLANKRMVEFEEAQAYAEENSLLFMETSAKTAMNVNDI 489

 Score = 38.9 bits (89), Expect(2) = 7e-22,   Method: Compositional matrix adjust.
 Identities = 19/42 (45%), Positives = 27/42 (64%)
 Frame = +2

Query: 10 IKMVVVGNGAVGKSSMIQRYCKGIFTKDYKKTIGVDFLERQI 51
           K+V++G  AVGKSS++ R+ KG F +  + TIG  F  RQ 
Sbjct: 32 FKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAF*LRQF 157
>07580
          Length = 921

 Score = 91.7 bits (226), Expect(2) = 2e-21,   Method: Compositional matrix adjust.
 Identities = 51/149 (34%), Positives = 82/149 (55%), Gaps = 2/149 (1%)
 Frame = +3

Query: 30  CKGIFTKDYKKTIGVDFLERQIQVNDEDVRLMLWDTAGQEEFDAITKAYYRGAQACVLVF 89
           CKGIF + Y  TI  D   +Q++V+ +   L + DTAG E+F A+   Y +  Q  +L +
Sbjct: 123 CKGIFVEKYDPTIE-DSYRKQVEVDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFLLAY 299

Query: 90  STTDRESFEAISSWREKV--VAEVGDIPTALVQNKIDLLDDSCIKNEEAEGLAKRLKLRF 147
           S T + +F  +   RE++  V +  D+P  LV NK DL D+  +  ++ +GLA+     F
Sbjct: 300 SITAQSTFNDLQELREQILRVKDTDDVPMLLVGNKCDLEDERVVGKDQGQGLARSFSCAF 479

Query: 148 YRTSVKEDLNVSEVFKYLAEKHLQKLKQQ 176
             TS K  +NV+E+F  L  +  +K  +Q
Sbjct: 480 LETSAKARINVNEIFMDLVRQINKKSPEQ 566

 Score = 27.3 bits (59), Expect(2) = 2e-21,   Method: Compositional matrix adjust.
 Identities = 11/24 (45%), Positives = 19/24 (79%)
 Frame = +2

Query: 11 KMVVVGNGAVGKSSMIQRYCKGIF 34
          K+VV+G+G VGKS++  ++ +G F
Sbjct: 65 KLVVLGSGGVGKSALTVQFVQGDF 136
>13901
          Length = 962

 Score = 95.9 bits (237), Expect = 1e-20,   Method: Compositional matrix adjust.
 Identities = 41/98 (41%), Positives = 67/98 (68%), Gaps = 1/98 (1%)
 Frame = -3

Query: 7   EVAIKMVVVGNGAVGKSSMIQRYCKGIFTKDYKKTIGVDFLERQIQVNDE-DVRLMLWDT 65
           EV  K++++G+  VGK+S +QRY    F +DYK TIGVDF  + I+ +D+ +++L LWD 
Sbjct: 294 EVLFKVIIIGDPTVGKTSFVQRYVNDSFRRDYKMTIGVDFALKVIRWSDKCNIKLQLWDI 115

Query: 66  AGQEEFDAITKAYYRGAQACVLVFSTTDRESFEAISSW 103
           AGQE F ++T+ YY+ A AC+++F  T + +++    W
Sbjct: 114 AGQERFTSMTRVYYKDAHACIVMFDLTQKNTYQNAIRW 1
>26083
          Length = 432

 Score = 92.8 bits (229), Expect = 9e-20,   Method: Compositional matrix adjust.
 Identities = 46/113 (40%), Positives = 67/113 (59%), Gaps = 1/113 (0%)
 Frame = +1

Query: 11  KMVVVGNGAVGKSSMIQRYCKGIFTKDYKKTIGVDFLERQIQVNDEDVRLMLWDTAGQEE 70
           K+V +G  +VGK+S+I R+    F   Y+ TIG+DFL + + + D  +RL LWDTAGQE 
Sbjct: 82  KLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTIRLQLWDTAGQER 261

Query: 71  FDAITKAYYRGAQACVLVFSTTDRESFEAISSWREKVVAEVG-DIPTALVQNK 122
           F ++  +Y R +   V+V+  T+  SF   S W + V  E G D+   LV NK
Sbjct: 262 FRSLIPSYIRDSSVAVVVYDITNANSFHQTSKWIDDVRTERGSDVIIMLVGNK 420
>01972
          Length = 2359

 Score = 75.5 bits (184), Expect(2) = 2e-18,   Method: Compositional matrix adjust.
 Identities = 41/146 (28%), Positives = 70/146 (47%)
 Frame = +3

Query: 36  KDYKKTIGVDFLERQIQVNDEDVRLMLWDTAGQEEFDAITKAYYRGAQACVLVFSTTDRE 95
           K Y  T+GV+        +   ++  +WDTAGQE+F  +   YY   Q  V++F  T R 
Sbjct: 381 KKYVATLGVEVHPLLFHTSRGKLKFNVWDTAGQEKFGGLRDGYYIQGQCAVIMFDVTSRV 560

Query: 96  SFEAISSWREKVVAEVGDIPTALVQNKIDLLDDSCIKNEEAEGLAKRLKLRFYRTSVKED 155
           +++ + +W   +V    +IP  L  NK+D+ D       +A    ++  L++Y  S K +
Sbjct: 561 TYKNVPNWHRDLVRVCENIPIVLCGNKVDIKDRKV--KAKAIVFHRKKNLQYYDISAKSN 734

Query: 156 LNVSEVFKYLAEKHLQKLKQQITEDP 181
            N  + F +LA K +     +  E P
Sbjct: 735 YNFEKPFLWLARKLVGDPNLEFVEMP 812

 Score = 33.9 bits (76), Expect(2) = 2e-18,   Method: Compositional matrix adjust.
 Identities = 13/33 (39%), Positives = 23/33 (69%)
 Frame = +1

Query: 5   DMEVAIKMVVVGNGAVGKSSMIQRYCKGIFTKD 37
           + E   K+V+VG+G VGK++ ++R+  G F K+
Sbjct: 289 EQEPTFKLVLVGDGGVGKTTFVKRHVTGEFEKN 387
>11728
          Length = 635

 Score = 79.0 bits (193), Expect = 2e-15,   Method: Compositional matrix adjust.
 Identities = 43/121 (35%), Positives = 64/121 (52%), Gaps = 1/121 (0%)
 Frame = -1

Query: 9   AIKMVVVGNGAVGKSSMIQRYCKGIFTKDYKKTIGVDFLERQIQVNDEDVRLMLWDTAGQ 68
           AIK VVVG+GAVGK+ ++  Y    F  +Y  T+  D     + V+ + + L LWDTAGQ
Sbjct: 491 AIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTV-FDNYSANVMVDSKPINLGLWDTAGQ 315

Query: 69  EEFDAITKAYYRGAQACVLVFSTTDRESFEAI-SSWREKVVAEVGDIPTALVQNKIDLLD 127
           E++D +    Y      ++ FS     SFE + + W  +V     + P  LV  K+DL +
Sbjct: 314 EDYDRLRPLSYPQTDVFLICFSLISPASFENVKAKWYPEVSHHCPNTPIILVGTKLDLRE 135

Query: 128 D 128
           D
Sbjct: 134 D 132
>33794
          Length = 779

 Score = 78.2 bits (191), Expect = 3e-15,   Method: Compositional matrix adjust.
 Identities = 42/129 (32%), Positives = 66/129 (51%)
 Frame = -1

Query: 44  VDFLERQIQVNDEDVRLMLWDTAGQEEFDAITKAYYRGAQACVLVFSTTDRESFEAISSW 103
           V +    I +  + V+L +WDT+GQ  F  I ++Y RGAQ  +LV+  T++ SF+ I  W
Sbjct: 692 VAYKTTTILLEGKRVKLQIWDTSGQGRFCTIIRSYSRGAQGIILVYDITNKWSFDGIDRW 513

Query: 104 REKVVAEVGDIPTALVQNKIDLLDDSCIKNEEAEGLAKRLKLRFYRTSVKEDLNVSEVFK 163
            ++V      IP  LV N++ L     +  ++AE  A R  +  +  S   D N+ E F 
Sbjct: 512 LKEVEEHAPGIPKVLVGNRLHLAYKRQVAAKQAETYASRNNMSCFEISPLCDFNIRESFC 333

Query: 164 YLAEKHLQK 172
            LA   L +
Sbjct: 332 ELARMALHR 306
>19006
          Length = 568

 Score = 75.5 bits (184), Expect = 2e-14,   Method: Compositional matrix adjust.
 Identities = 43/125 (34%), Positives = 68/125 (54%), Gaps = 1/125 (0%)
 Frame = -2

Query: 11  KMVVVGNGAVGKSSMIQRYCKGIFTKDYKKTIGVDFLERQIQVNDEDVRLMLWDTAGQEE 70
           K+V+VG+GA GK+ ++  + K  F + Y  T+  +++   I+V+ + V L LWDTAGQE+
Sbjct: 432 KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVA-DIEVDSKQVELALWDTAGQED 256

Query: 71  FDAITKAYYRGAQACVLVFSTTDRESFEAISS-WREKVVAEVGDIPTALVQNKIDLLDDS 129
           +D +    Y      ++ FS    +S E I   W  +V     ++P  LV NK DL +D 
Sbjct: 255 YDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVRHFCPNVPIILVGNKKDLRNDE 76

Query: 130 CIKNE 134
             K E
Sbjct: 75  NTKRE 61
>11257
          Length = 1102

 Score = 74.7 bits (182), Expect = 3e-14,   Method: Compositional matrix adjust.
 Identities = 41/143 (28%), Positives = 81/143 (56%), Gaps = 6/143 (4%)
 Frame = -2

Query: 48   ERQIQVNDEDVRLMLWDTAGQEEFDAITKAYYRGAQACVLVFSTTDRESFEAISSWREKV 107
             + + V+ E   + +WDTAGQE + ++   +YRG   C+L FS  + +S +++S W ++ 
Sbjct: 1056 HKDVVVDGETFTMQIWDTAGQERYKSLRTPFYRGTDCCLLTFSVDNLKSLQSLSDWYDEF 877

Query: 108  V--AEVGD---IPTALVQNKIDLLDDSCIKNEEAEGLAK-RLKLRFYRTSVKEDLNVSEV 161
            V  A++ D    P  ++ NK D +++  + +E+A    +    L ++ TS K+ LNV + 
Sbjct: 876  VNYADIQDSASFPFVIIGNKAD-IEEREVSSEDAYNWCRTHGNLPYFETSAKDSLNVQQA 700

Query: 162  FKYLAEKHLQKLKQQITEDPEQT 184
            F  +  + L+++ +Q+ E P +T
Sbjct: 699  FLAVV-RRLREMDEQMDERPTRT 634
>13750
          Length = 503

 Score = 72.8 bits (177), Expect = 1e-13,   Method: Compositional matrix adjust.
 Identities = 45/147 (30%), Positives = 74/147 (50%), Gaps = 2/147 (1%)
 Frame = -2

Query: 22  KSSMIQRYCKGIFTKDYKKTIGVDFLE-RQIQVNDEDVRLMLWDTAGQEEFDAITKAYYR 80
           K+ +++RY KG F      TI V   E  + + +  +VR  LWDT G E + ++  +++R
Sbjct: 502 KTCLLRRYQKGFFMDRTMPTIAVLCSEFNESRTDPLNVRYTLWDTGGAETYRSLWVSHFR 323

Query: 81  GAQACVLVFSTTDRESF-EAISSWREKVVAEVGDIPTALVQNKIDLLDDSCIKNEEAEGL 139
           GAQ  +LV+  T   SF  A + WR+ ++  + +     V +K DL ++  I  E  +  
Sbjct: 322 GAQVALLVYDVTCEWSFLTATTVWRKALMKNIPEAQVIFVGSKTDLEENRVISTERGQAF 143

Query: 140 AKRLKLRFYRTSVKEDLNVSEVFKYLA 166
           A +    F+ TS     NV  VF  +A
Sbjct: 142 ATQCGYTFFETSSVTGKNVDAVFWEIA 62
>19656
          Length = 428

 Score = 70.1 bits (170), Expect = 8e-13,   Method: Compositional matrix adjust.
 Identities = 39/100 (39%), Positives = 53/100 (53%), Gaps = 1/100 (1%)
 Frame = +3

Query: 9   AIKMVVVGNGAVGKSSMIQRYCKGIFTKDYKKTIGVDFLERQIQVNDEDVRLMLWDTAGQ 68
           AIK VVVG+GAVGK+ ++  Y    F  +Y  T+  D     + V+   V L LWDTAGQ
Sbjct: 111 AIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTV-FDNYSANVMVDGRPVNLGLWDTAGQ 287

Query: 69  EEFDAITKAYYRGAQACVLVFSTTDRESFEAI-SSWREKV 107
           E++D +    Y      +L FS     SFE I + W  +V
Sbjct: 288 EDYDRLRPLSYPQTDVFLLCFSVASPASFENIRAKWYPEV 407
>34359
          Length = 1042

 Score = 68.9 bits (167), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 35/118 (29%), Positives = 62/118 (52%)
 Frame = +3

Query: 10  IKMVVVGNGAVGKSSMIQRYCKGIFTKDYKKTIGVDFLERQIQVNDEDVRLMLWDTAGQE 69
            K+V+VG      +++++R+  G   K Y  T+GV+    Q   +   +R  +WDTAGQE
Sbjct: 54  FKLVLVGGRWEWANNIVKRHVTGS*-KKYVATLGVEVHPLQFNTSRGLLRFNVWDTAGQE 230

Query: 70  EFDAITKAYYRGAQACVLVFSTTDRESFEAISSWREKVVAEVGDIPTALVQNKIDLLD 127
           +F  +   YY      +++F  T R +++ + +W   +V    +IP  L  NK+D+ D
Sbjct: 231 KFGGLRDGYYIQGTCAIIMFDVTSRVTYKNVPNWHRDLVRVCENIPIVLCGNKVDIKD 404
>27191
          Length = 443

 Score = 67.4 bits (163), Expect = 5e-12,   Method: Compositional matrix adjust.
 Identities = 33/103 (32%), Positives = 57/103 (55%), Gaps = 1/103 (0%)
 Frame = +1

Query: 22  KSSMIQRYCKGIFTKDYKKTIGVDFLERQIQVNDEDVRLMLWDTAGQEEFDAITKAYYRG 81
           K+ +I+ +C+  F + Y+ T+GVD+  +   VN  D+R+ +WD +G  E+  +    Y G
Sbjct: 1   KTCLIKHFCESKFNQGYQPTVGVDYGFKIQTVNGVDMRVHMWDLSGSNEYLDVRNELYTG 180

Query: 82  AQACVLVFSTTDRESFEAISSW-REKVVAEVGDIPTALVQNKI 123
           + A  +VF  ++  SFEA+ SW RE      G     +V N++
Sbjct: 181 SDAIFIVFDVSNTPSFEALDSWLREINRFATGSPLNVIVGNRV 309
>26536
          Length = 829

 Score = 66.2 bits (160), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 40/111 (36%), Positives = 56/111 (50%), Gaps = 3/111 (2%)
 Frame = +2

Query: 58  VRLMLWDTAGQEEFDAITKAYYRGAQACVLVFSTTDRESF---EAISSWREKVVAEVGDI 114
           V     DTAGQEE+ ++ + Y R     ++V+S TD  SF   EA+  W  +   E   I
Sbjct: 128 VSWTFLDTAGQEEYSSMREHYTRSGDGFIVVYSVTDVTSFQEAEAVFRWLTRFQDET-SI 304

Query: 115 PTALVQNKIDLLDDSCIKNEEAEGLAKRLKLRFYRTSVKEDLNVSEVFKYL 165
              L  NK DL  D  +  EE   +A RL + ++ TS K   NVS+V+  L
Sbjct: 305 HAVLCGNKTDLTSDRKVTPEEGRKMADRLGMLYFETSAKTGDNVSQVYHGL 457

 Score = 33.1 bits (74), Expect = 0.11,   Method: Compositional matrix adjust.
 Identities = 18/46 (39%), Positives = 28/46 (60%)
 Frame = +2

Query: 11  KMVVVGNGAVGKSSMIQRYCKGIFTKDYKKTIGVDFLERQIQVNDE 56
           K+V++G+G VGKSS+  R+ +  F   Y  TI  D   + IQV+ +
Sbjct: 491 KIVMLGSGGVGKSSLTIRFTQDTFLDVYDPTI-EDSYRKMIQVSGQ 625
>33380
          Length = 282

 Score = 66.2 bits (160), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 33/75 (44%), Positives = 45/75 (60%), Gaps = 1/75 (1%)
 Frame = +3

Query: 55  DEDVRLMLWDTAGQEEFDAITKAYYRGAQACVLVFSTTDRESFEAISSWREKVVAEVGD- 113
           D+ V+L +WDTAGQE +  IT AYYRGA   +L++  T+ ESF A+  W  ++     D 
Sbjct: 51  DKRVKLQIWDTAGQERYRTITTAYYRGAMGFILMYDVTNEESFNAVQDWCTQIKTYSWDN 230

Query: 114 IPTALVQNKIDLLDD 128
               LV NK DL D+
Sbjct: 231 AQVVLVGNKCDLEDE 275
>32723
          Length = 384

 Score = 65.5 bits (158), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 36/100 (36%), Positives = 56/100 (56%), Gaps = 1/100 (1%)
 Frame = +2

Query: 68  QEEFDAITKAYYRGAQACVLVFSTTDRESFEAISSWREKVVAEVG-DIPTALVQNKIDLL 126
           QE F +IT++YYR A A +LV+    ++S+E++  W  ++    G  +   LV NKID  
Sbjct: 2   QERFRSITQSYYRSANALILVYDVCSQQSYESLPQWIHEIELYAGTKVLAFLVGNKIDQT 181

Query: 127 DDSCIKNEEAEGLAKRLKLRFYRTSVKEDLNVSEVFKYLA 166
           D   I     +  A+R ++RF  TS KE  NV ++F  +A
Sbjct: 182 DKREIPTHIGKEFAERYEMRFLETSAKEADNVEKLFSTIA 301
>13745
          Length = 1045

 Score = 65.1 bits (157), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 39/134 (29%), Positives = 69/134 (51%), Gaps = 9/134 (6%)
 Frame = +2

Query: 68  QEEFDAITKAYYRGAQACVLVFSTTDRESFEAISSWREKVVAEVGD-----IPTALVQNK 122
           QE F ++  A+YRGA  CVLV+  T   SF+ + SWR++ + +         P  ++ NK
Sbjct: 2   QERFQSLGVAFYRGADCCVLVYDVTAPNSFKNLDSWRDEFLIQASPRDPEHFPFVVLGNK 181

Query: 123 IDLLDDSCIKNEEAEGLAKRLKLRFYRTSVKEDLNVSEVFKYLAEKHLQKLKQQ--ITED 180
           +DL +         +    +  + +Y TS KE +NV   F+ +A+  L++  +   I + 
Sbjct: 182 VDLDNRQVSTRRAQQWCQSKNDIPYYETSAKEGINVEMAFQTIAKNALEQETEAELINDF 361

Query: 181 PEQT--HSSSNKIG 192
           P+Q   +S +N+ G
Sbjct: 362 PDQIRLNSENNRPG 403
>12339
          Length = 578

 Score = 64.7 bits (156), Expect = 3e-11,   Method: Compositional matrix adjust.
 Identities = 36/129 (27%), Positives = 74/129 (57%), Gaps = 7/129 (5%)
 Frame = -2

Query: 68  QEEFDAITKAYYRGAQACVLVFSTTDRESFEAISSWREKVVAEVGD-----IPTALVQNK 122
           QE F ++  A+YRGA  C+LV+  T+ ++F+++ SW+ + + +         P  ++ NK
Sbjct: 577 QERFQSLGVAFYRGADCCILVYDVTEXKTFDSLDSWQREFLNQASPRDPEHFPFVVIGNK 398

Query: 123 IDLLDDSCIKNEEAEGL-AKRLKLRFYRTSVKEDLNVSEVFKYLAEKHL-QKLKQQITED 180
           ID LD+  +  +  +G  + +  + ++ TS KE +NV + F+ +A+  L Q+ + +I + 
Sbjct: 397 ID-LDNRVVTAKRGQGWCSTKGGIPYFETSAKEAINVEQAFQTVAKNALAQESEVEIDDF 221

Query: 181 PEQTHSSSN 189
           P +   S++
Sbjct: 220 PSEIRLSND 194
>00858
          Length = 1658

 Score = 60.1 bits (144), Expect = 7e-10,   Method: Compositional matrix adjust.
 Identities = 41/146 (28%), Positives = 76/146 (52%), Gaps = 2/146 (1%)
 Frame = -2

Query: 22   KSSMIQRYCKGIFTKDYKKTIGVDFLERQIQVNDEDVRLMLWDTAGQEEFDAITKAYYRG 81
            KS++  +  +  F ++Y  T   D   +Q+ ++ E   L + DTAGQEE  A+     R 
Sbjct: 1552 KSALTIQLXQNHFVEEYDPTXE-DSXRKQVVIDGETCLLDILDTAGQEEXSAMRDQCMRT 1376

Query: 82   AQACVLVFSTTDRESFEAISSWREKV--VAEVGDIPTALVQNKIDLLDDSCIKNEEAEGL 139
             +  + VF+  + +SFE I+ +RE++  V +  ++P  LV NK+DL   + ++  + + +
Sbjct: 1375 GEGFLCVFAVXNLKSFEDINQYREQIKRVKDADEVPMVLVGNKVDLPIRN-VEQRQGKHM 1199

Query: 140  AKRLKLRFYRTSVKEDLNVSEVFKYL 165
            A+   + +  TS K    V + F  L
Sbjct: 1198 AELYHIPYVETSAKTRQGVDDAFYTL 1121
>19046
          Length = 445

 Score = 59.7 bits (143), Expect = 9e-10,   Method: Compositional matrix adjust.
 Identities = 35/98 (35%), Positives = 53/98 (54%), Gaps = 3/98 (3%)
 Frame = -2

Query: 68  QEEFDAITKAYYRGAQACVLVFSTTDRESFEAISSWREKV--VAEVGDIPTALVQNKIDL 125
           QEEF A+ + Y R     +LVFS TD  SFE ++++  ++  V +    P  L  NK+DL
Sbjct: 444 QEEFSAMREQYMRKGDGFLLVFSVTDFRSFENMANFHTQILRVKDRDSYPMILCANKVDL 265

Query: 126 LDDSCIKNEEAEGLAKRLKLRFYRTSVKE-DLNVSEVF 162
           +    +  E+   LA RL++ +  TS K+  LNV   F
Sbjct: 264 VHQRKVSEEQVRDLATRLRIPYIETSAKDPPLNVDLAF 151
>24619
          Length = 509

 Score = 57.8 bits (138), Expect = 4e-09,   Method: Compositional matrix adjust.
 Identities = 34/98 (34%), Positives = 52/98 (53%), Gaps = 3/98 (3%)
 Frame = -2

Query: 68  QEEFDAITKAYYRGAQACVLVFSTTDRESFEAISSWREKV--VAEVGDIPTALVQNKIDL 125
           QEEF A+ + Y R     +LVFS  D +SFE + ++  ++  V +    P  L  NK+DL
Sbjct: 508 QEEFSAMREQYMRKGDGFLLVFSVIDYQSFENMVNFHTQILRVKDRDTYPMILCANKVDL 329

Query: 126 LDDSCIKNEEAEGLAKRLKLRFYRTSVKE-DLNVSEVF 162
           +    +  E+   LA RL++ +  TS K+  LNV   F
Sbjct: 328 VHQRKVSEEQVRDLATRLRIPYIETSAKDPPLNVDLAF 215
>36482
          Length = 686

 Score = 57.4 bits (137), Expect = 5e-09,   Method: Compositional matrix adjust.
 Identities = 40/128 (31%), Positives = 62/128 (48%), Gaps = 4/128 (3%)
 Frame = +2

Query: 53  VNDEDVRLMLWDTAGQEEFDAITKAYYRGAQACVLVFSTTDRESFEAISSWREKV--VAE 110
           + D+DVRL + DTAGQ  +    + Y   A   V V+S  DR+S+E +   + +V  V +
Sbjct: 83  IEDDDVRLEILDTAGQGTY-PWKEGYALWADCFVFVYSINDRQSYEELVQVKRQVESVRK 259

Query: 111 VGDIPTALVQNKIDLLDDSCIKNEEAEGLAKRLKLRFYRTSVKEDLNVSEVFKYLAE--K 168
              +   L  NK DLL D  +  +E E LA+ +  R Y  S  E   +  +     +  +
Sbjct: 260 STSLTAVLAANKTDLLHDRQVTQKEGEDLAEEIGCRLYEVSASEGSQMEAITSMFHDLYR 439

Query: 169 HLQKLKQQ 176
             +K KQQ
Sbjct: 440 EFRKHKQQ 463
>01398
          Length = 1421

 Score = 55.5 bits (132), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 31/109 (28%), Positives = 53/109 (48%), Gaps = 2/109 (1%)
 Frame = -2

Query: 68   QEEFDAITKAYYRGAQACVLVFSTTDRESFEAISSWREKVVAEVGDIPTAL--VQNKIDL 125
            QE F +IT++YYR +   ++V+  T R +FE +  W E+    +         + +K D 
Sbjct: 1420 QERFRSITRSYYRNSVGVIIVYDITKRSTFENLKQWYEEARNHIEPHKAIFLVLGHKSDR 1241

Query: 126  LDDSCIKNEEAEGLAKRLKLRFYRTSVKEDLNVSEVFKYLAEKHLQKLK 174
             D   +   E    A+   L+F+ TS K   N+ +VF  +A+   Q L+
Sbjct: 1240 EDARQVTAREGRRFAEMHGLKFFETSAKSGHNIEDVFAQIAKDTYQHLQ 1094
>34597
          Length = 773

 Score = 51.2 bits (121), Expect = 4e-07,   Method: Compositional matrix adjust.
 Identities = 31/109 (28%), Positives = 53/109 (48%), Gaps = 2/109 (1%)
 Frame = -2

Query: 77  AYYRGAQACVLVFSTTDRESFEAISSWREKVVAEVG-DIPTALVQNKIDLLDDSCIKNEE 135
           ++  G  AC++      ++SFE I  W   +      D+   ++ NK D+ D   +  E 
Sbjct: 760 SWSDGHNACLMT*RM--KKSFENIVKWLRNIDEHANEDVEKMILGNKCDMTDKRVVSKER 587

Query: 136 AEGLAKRLKLRFYRTSVKEDLNVSEVFKYLAEKHLQKLK-QQITEDPEQ 183
            E +A+   +RF  TS K ++N+   F  LAE  L K   ++  E+PE+
Sbjct: 586 GEAIAREHSIRFMETSAKSNINIERAFCELAEAILDKTAGRESAENPER 440
>09204
          Length = 1051

 Score = 50.4 bits (119), Expect = 6e-07,   Method: Compositional matrix adjust.
 Identities = 29/106 (27%), Positives = 53/106 (50%), Gaps = 4/106 (3%)
 Frame = -3

Query: 71   FDAITKAYYRGAQACVLVFSTTDRESFEAISSWREKVVAEVGDIPTALVQNKIDLLDDS- 129
            ++A+++ YYRGA+A +L F  TD+ SF+ I  W  ++     +    +   K DL+ D  
Sbjct: 1046 YEAMSRIYYRGAKAAILCFDLTDKSSFDRIRFWIGELRQHEEECKLYICGTKFDLVHDDP 867

Query: 130  ---CIKNEEAEGLAKRLKLRFYRTSVKEDLNVSEVFKYLAEKHLQK 172
                +    A+ LA       Y TS     N+ ++F  +AE ++++
Sbjct: 866  ERRAVPRSVAKALADDCMAEIYETSSMTGDNIEKLFTKIAEDYMKE 729
>00552
          Length = 455

 Score = 49.7 bits (117), Expect = 9e-07,   Method: Compositional matrix adjust.
 Identities = 18/47 (38%), Positives = 31/47 (65%)
 Frame = -3

Query: 62  LWDTAGQEEFDAITKAYYRGAQACVLVFSTTDRESFEAISSWREKVV 108
           +WDTAGQE + ++   +YRG   C+L FS  + +S +++S W ++ V
Sbjct: 147 IWDTAGQERYKSLRTPFYRGTDCCLLTFSVDNLKSLQSLSDWYDEFV 7

 Score = 42.4 bits (98), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 19/47 (40%), Positives = 31/47 (65%)
 Frame = -1

Query: 10  IKMVVVGNGAVGKSSMIQRYCKGIFTKDYKKTIGVDFLERQIQVNDE 56
           +K+V++G+G VGKSS++ R+    F      TIGV+FL + + V+ E
Sbjct: 443 LKVVLLGDGGVGKSSLMNRFVSNKFDAQSFHTIGVEFLTKDVVVDGE 303
>35581
          Length = 364

 Score = 47.8 bits (112), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 26/98 (26%), Positives = 50/98 (51%), Gaps = 1/98 (1%)
 Frame = +2

Query: 10  IKMVVVGNGAVGKSSMIQRYCKGIFTKDYKKTIGVDFLERQIQVNDEDVRLM-LWDTAGQ 68
            K V++G+  VGK+ ++ R     F      ++    L   + +    +  + LWDTAGQ
Sbjct: 47  FKCVLLGDAGVGKTCLLNRLATDKFLDSPLTSLTTASLLTTVTLTSGVMASVDLWDTAGQ 226

Query: 69  EEFDAITKAYYRGAQACVLVFSTTDRESFEAISSWREK 106
           E + ++T +YYR  +A ++V+   D E    ++ W ++
Sbjct: 227 ERYRSLTSSYYRDTKAVLIVY---DAEHKLKLTDWTDR 331
>14775
          Length = 380

 Score = 47.4 bits (111), Expect = 6e-06,   Method: Compositional matrix adjust.
 Identities = 25/72 (34%), Positives = 41/72 (56%), Gaps = 1/72 (1%)
 Frame = -2

Query: 22  KSSMIQRYCKGIFTKDYKKTIGVDFLE-RQIQVNDEDVRLMLWDTAGQEEFDAITKAYYR 80
           K+ +++RY KG F      TI V   E  + + +  +VR  LWDT G E + ++  +++R
Sbjct: 379 KTCLLRRYQKGFFMDRTMPTIAVLCSEFNESRTDPLNVRYTLWDTGGAETYRSLWVSHFR 200

Query: 81  GAQACVLVFSTT 92
           GAQ  +LV+  T
Sbjct: 199 GAQVALLVYDVT 164
>31291
          Length = 446

 Score = 46.6 bits (109), Expect = 8e-06,   Method: Compositional matrix adjust.
 Identities = 32/118 (27%), Positives = 50/118 (42%), Gaps = 14/118 (11%)
 Frame = -1

Query: 60  LMLWDTAGQEEFDAITKAYYRGAQACVLVFSTTDRESFEAIS-SWREKVVAEVGDIPTAL 118
           L LWDTAGQE++D +    Y      +L FS     S + +   W  ++      +P  L
Sbjct: 446 LQLWDTAGQEDYDRLRPLAYPNTDVFMLXFSLMSEASMKNVKVKWYPEIRHHDPHVPIVL 267

Query: 119 VQNKIDLLDD------------SCIKNEEAEGLAKRLKL-RFYRTSVKEDLNVSEVFK 163
           V  K+DL  D              + + +   LAK +K  R++  S K   N+   F+
Sbjct: 266 VGTKLDLRQDKEAVRKLRSSRQDPVSSNQGNDLAKAIKAKRYFECSSKTQENLKTAFE 93
>10708
          Length = 2775

 Score = 38.5 bits (88), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 17/44 (38%), Positives = 23/44 (52%)
 Frame = -2

Query: 58   VRLMLWDTAGQEEFDAITKAYYRGAQACVLVFSTTDRESFEAIS 101
            V L LWDTAGQE++D +    Y      ++ FS    +S E I 
Sbjct: 2723 VELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIP 2592
>08153
          Length = 1703

 Score = 37.0 bits (84), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 20/86 (23%), Positives = 43/86 (50%)
 Frame = +1

Query: 10  IKMVVVGNGAVGKSSMIQRYCKGIFTKDYKKTIGVDFLERQIQVNDEDVRLMLWDTAGQE 69
           +++++VG  A GK++++ +   G        TIG +       V  +++   +WD  GQ+
Sbjct: 85  VRILMVGLDAAGKTTILYKLKLGEIVTTIP-TIGFNVE----TVEYKNISFTVWDVGGQD 249

Query: 70  EFDAITKAYYRGAQACVLVFSTTDRE 95
           +   + + Y++  Q  + V  + DRE
Sbjct: 250 KIRPLWRHYFQNTQGLIFVVDSNDRE 327
>10862
          Length = 2896

 Score = 36.6 bits (83), Expect = 0.009,   Method: Compositional matrix adjust.
 Identities = 18/74 (24%), Positives = 34/74 (45%), Gaps = 2/74 (2%)
 Frame = -3

Query: 56   EDVRLMLWDTAGQEEFDAITKAYYRGAQACVLVFSTTDRESFEAISSWREKVV--AEVGD 113
            ++ +  +WD  GQ++   + + YY G Q  + V    DR+  +       +++   E+ D
Sbjct: 2492 QECQFNVWDVGGQDKIRPLWRHYYTGTQGLIFVVDCADRDRIDEARQELHRIINDREMRD 2313

Query: 114  IPTALVQNKIDLLD 127
                +  NK DL D
Sbjct: 2312 AIILIFANKQDLPD 2271
>09827
          Length = 1201

 Score = 35.0 bits (79), Expect = 0.026,   Method: Compositional matrix adjust.
 Identities = 19/86 (22%), Positives = 43/86 (50%)
 Frame = -3

Query: 10   IKMVVVGNGAVGKSSMIQRYCKGIFTKDYKKTIGVDFLERQIQVNDEDVRLMLWDTAGQE 69
            +++++VG  A GK++++ +   G        TIG +       V  +++   +WD  GQ+
Sbjct: 1112 MRILMVGLDAAGKTTILYKLKLGEIVTTIP-TIGFNVE----TVEYKNISFTVWDVGGQD 948

Query: 70   EFDAITKAYYRGAQACVLVFSTTDRE 95
            +   + + Y++  Q  + V  + D+E
Sbjct: 947  KIRPLWRHYFQNTQGLIFVVDSNDKE 870
>00822
          Length = 1294

 Score = 31.6 bits (70), Expect = 0.31,   Method: Compositional matrix adjust.
 Identities = 16/43 (37%), Positives = 23/43 (53%)
 Frame = +1

Query: 86  VLVFSTTDRESFEAISSWREKVVAEVGDIPTALVQNKIDLLDD 128
           V VF    R  FE I SW+EK++++  +    LVQ  I  L +
Sbjct: 781 VCVFHFVSRSVFEEICSWKEKILSKEENSWLCLVQLXILYLSE 909
>06994
          Length = 429

 Score = 31.2 bits (69), Expect = 0.35,   Method: Compositional matrix adjust.
 Identities = 12/26 (46%), Positives = 21/26 (80%)
 Frame = +3

Query: 11 KMVVVGNGAVGKSSMIQRYCKGIFTK 36
          K+VV+G+G VGKS++  ++ +GIF +
Sbjct: 60 KLVVLGSGGVGKSALTVQFVQGIFVE 137
>17872
          Length = 700

 Score = 30.0 bits (66), Expect = 0.78,   Method: Compositional matrix adjust.
 Identities = 25/108 (23%), Positives = 42/108 (38%), Gaps = 13/108 (12%)
 Frame = -1

Query: 68  QEEFDAITKAYYRGAQACVLVFSTTDRESFE-AISSWREKVVAEVGDIPTALVQNKIDLL 126
           Q++FD++    Y      +L FS     SF   +  W  ++       P  +V  + DL 
Sbjct: 700 QDDFDSLRPLCYPETNVFLLCFSVVSPTSFHNVMEKWVPELRYHCPGAPLVVVGTQSDLR 521

Query: 127 DD------------SCIKNEEAEGLAKRLKLRFYRTSVKEDLNVSEVF 162
           +D              +  EEA  +A +L  ++   S     N+ EVF
Sbjct: 520 NDVKVLIELAKYKEKPVSEEEAVKMADQLGAQYVECSALTQKNLKEVF 377
>33605
          Length = 888

 Score = 28.9 bits (63), Expect = 1.9,   Method: Compositional matrix adjust.
 Identities = 19/90 (21%), Positives = 42/90 (46%), Gaps = 2/90 (2%)
 Frame = +1

Query: 7   EVAIKMVVVGNGAVGKSSMIQRYCKGIFTKDYKKTIGVDF--LERQIQVNDEDVRLMLWD 64
           E  ++++++G    GK+++++++  G        T+G +   LE +        +L +WD
Sbjct: 490 EKEVRLLMLGLDNAGKTTILKKF-NGEDIDTISPTLGFNIKTLEHR------GFKLNVWD 648

Query: 65  TAGQEEFDAITKAYYRGAQACVLVFSTTDR 94
             GQ+   +  + Y+      V V  + DR
Sbjct: 649 VGGQQSLRSYWRNYFESTDGLVWVVDSADR 738
>30174
          Length = 1384

 Score = 27.7 bits (60), Expect = 4.1,   Method: Compositional matrix adjust.
 Identities = 18/49 (36%), Positives = 24/49 (48%), Gaps = 8/49 (16%)
 Frame = -3

Query: 126  LDDSCIKNEEAEGLAKRL--------KLRFYRTSVKEDLNVSEVFKYLA 166
            LDD  IKN +AE L K L        +L F +   K DL  ++ F +L 
Sbjct: 1352 LDDILIKNSDAEALTKDLHFVQETLFRLGFIQNLAKSDLIPNQRFSHLG 1206
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|9790227|ref|NP_062747.1| RAB9, member RAS oncogene
family [Mus musculus]
         (201 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

14456                                                                 263   5e-71
11257                                                                 201   1e-53
17511                                                                 157   3e-39
13745                                                                 130   4e-31
08428                                                                 125   1e-29
12339                                                                 124   2e-29
34468                                                                 108   1e-24
05468                                                                 102   1e-22
00552                                                                  99   2e-21
01972                                                                  75   3e-20
07465                                                                  94   3e-20
33374                                                                  75   5e-20
26083                                                                  87   6e-18
07580                                                                  72   2e-16
13901                                                                  78   3e-15
11728                                                                  77   4e-15
34359                                                                  77   5e-15
13750                                                                  76   9e-15
19006                                                                  76   1e-14
35581                                                                  75   1e-14
19656                                                                  72   2e-13
19046                                                                  71   4e-13
24619                                                                  71   4e-13
00858                                                                  67   6e-12
30760                                                                  65   2e-11
01398                                                                  63   9e-11
31291                                                                  62   2e-10
26536                                                                  62   2e-10
33380                                                                  62   2e-10
10708                                                                  43   1e-09
27191                                                                  55   2e-08
32723                                                                  54   6e-08
14775                                                                  44   4e-05
17872                                                                  42   2e-04
31932                                                                  42   2e-04
18509                                                                  40   5e-04
01095                                                                  39   0.002
09827                                                                  34   0.041
08153                                                                  33   0.094
33605                                                                  32   0.16 
06994                                                                  30   0.68 
10862                                                                  29   1.4  
25796                                                                  28   2.3  
14677                                                                  28   2.4  
09576                                                                  27   3.9  
>14456
          Length = 1867

 Score =  263 bits (671), Expect = 5e-71,   Method: Compositional matrix adjust.
 Identities = 126/198 (63%), Positives = 154/198 (77%), Gaps = 4/198 (2%)
 Frame = -1

Query: 8    FKIIL---LGDGGVGKSSLMNRYVTNKFDSQLFHTIGVEFLNKDLEVDGHFVTMQIWDTA 64
             KI L   L  GGVGKSSLMNR+V+NKFD+Q FHTIGVEFLNKD+ VD    TMQIWDTA
Sbjct: 1147 LKITLDKQLKQGGVGKSSLMNRFVSNKFDAQSFHTIGVEFLNKDVVVDDETYTMQIWDTA 968

Query: 65   GQERFRSLRTPFYRGSDCCLLTFSVDDSQSFQNLSNWKKEFIYYADVKEPESFPFVILGN 124
            GQERF+SLRTPFYRG+DCCLLTFSVD  QSF+NLS W+KEF+YYAD+++  +FPFV+LGN
Sbjct: 967  GQERFKSLRTPFYRGADCCLLTFSVDSMQSFRNLSMWRKEFLYYADIQDGVTFPFVVLGN 788

Query: 125  KTDIKERQVSTEEAQAWCKDNGDYPYFETSAKDSTNVAAAFEEAVRRILATEDRSE-HLI 183
            K D++ RQV+ EEA++WC  N + PYFETSAKD+TNV  AF  AV+R+   ED+ E    
Sbjct: 787  KIDVEGRQVTNEEARSWCTANSNAPYFETSAKDATNVEKAFLAAVQRLREVEDQQEVKTA 608

Query: 184  QTDTVNLHRKPKPNSSCC 201
              +TV+L+R  +  SS C
Sbjct: 607  HGNTVDLNRAARGKSSSC 554
>11257
          Length = 1102

 Score =  201 bits (512), Expect(2) = 1e-53,   Method: Compositional matrix adjust.
 Identities = 95/157 (60%), Positives = 122/157 (77%), Gaps = 1/157 (0%)
 Frame = -2

Query: 46   NKDLEVDGHFVTMQIWDTAGQERFRSLRTPFYRGSDCCLLTFSVDDSQSFQNLSNWKKEF 105
            +KD+ VDG   TMQIWDTAGQER++SLRTPFYRG+DCCLLTFSVD+ +S Q+LS+W  EF
Sbjct: 1056 HKDVVVDGETFTMQIWDTAGQERYKSLRTPFYRGTDCCLLTFSVDNLKSLQSLSDWYDEF 877

Query: 106  IYYADVKEPESFPFVILGNKTDIKERQVSTEEAQAWCKDNGDYPYFETSAKDSTNVAAAF 165
            + YAD+++  SFPFVI+GNK DI+ER+VS+E+A  WC+ +G+ PYFETSAKDS NV  AF
Sbjct: 876  VNYADIQDSASFPFVIIGNKADIEEREVSSEDAYNWCRTHGNLPYFETSAKDSLNVQQAF 697

Query: 166  EEAVRRILATEDR-SEHLIQTDTVNLHRKPKPNSSCC 201
               VRR+   +++  E   +TDTV+L R  K  SSCC
Sbjct: 696  LAVVRRLREMDEQMDERPTRTDTVDLKRVAKVKSSCC 586

 Score = 25.4 bits (54), Expect(2) = 1e-53,   Method: Compositional matrix adjust.
 Identities = 10/12 (83%), Positives = 11/12 (91%)
 Frame = -3

Query: 36   LFHTIGVEFLNK 47
            +FHTIGVEFL K
Sbjct: 1085 VFHTIGVEFLTK 1050
>17511
          Length = 483

 Score =  157 bits (396), Expect = 3e-39,   Method: Compositional matrix adjust.
 Identities = 70/125 (56%), Positives = 93/125 (74%)
 Frame = -3

Query: 4   KSSLFKIILLGDGGVGKSSLMNRYVTNKFDSQLFHTIGVEFLNKDLEVDGHFVTMQIWDT 63
           K  L K+I+LGD GVGK+SLMN+YV  KF +Q   TIG +FL K++ VD   VTMQIWDT
Sbjct: 376 KKVLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQIWDT 197

Query: 64  AGQERFRSLRTPFYRGSDCCLLTFSVDDSQSFQNLSNWKKEFIYYADVKEPESFPFVILG 123
           AGQERF+SL   FYRG+DCC+L F V    +F++L +W+ EF+  A  ++PE+FPFV++G
Sbjct: 196 AGQERFQSLGVAFYRGADCCVLVFDVTMPNTFRSLDSWRDEFLIQASPRDPENFPFVVIG 17

Query: 124 NKTDI 128
           NK D+
Sbjct: 16  NKIDL 2
>13745
          Length = 1045

 Score =  130 bits (326), Expect = 4e-31,   Method: Compositional matrix adjust.
 Identities = 58/117 (49%), Positives = 77/117 (65%)
 Frame = +2

Query: 66  QERFRSLRTPFYRGSDCCLLTFSVDDSQSFQNLSNWKKEFIYYADVKEPESFPFVILGNK 125
           QERF+SL   FYRG+DCC+L + V    SF+NL +W+ EF+  A  ++PE FPFV+LGNK
Sbjct: 2   QERFQSLGVAFYRGADCCVLVYDVTAPNSFKNLDSWRDEFLIQASPRDPEHFPFVVLGNK 181

Query: 126 TDIKERQVSTEEAQAWCKDNGDYPYFETSAKDSTNVAAAFEEAVRRILATEDRSEHL 182
            D+  RQVST  AQ WC+   D PY+ETSAK+  NV  AF+   +  L  E  +E +
Sbjct: 182 VDLDNRQVSTRRAQQWCQSKNDIPYYETSAKEGINVEMAFQTIAKNALEQETEAELI 352
>08428
          Length = 1109

 Score =  125 bits (314), Expect = 1e-29,   Method: Compositional matrix adjust.
 Identities = 70/187 (37%), Positives = 106/187 (56%), Gaps = 1/187 (0%)
 Frame = -3

Query: 9    KIILLGDGGVGKSSLMNRYVTNKFDSQLFHTIGVEFLNKDLEVDGHFVTMQIWDTAGQER 68
            K+ LLGD GVGKSS++ R+VT  +      TIG  F++K L VDG     QIWDTAGQE+
Sbjct: 1065 KVCLLGDSGVGKSSIVLRFVTGSYRPSQESTIGASFMSKSLVVDGAGYRFQIWDTAGQEK 886

Query: 69   FRSLRTPFYRGSDCCLLTFSVDDSQSFQNLSNWKKEFIYYADVKEPESFPFVILGNKTDI 128
            FR+L   +YRG+   ++ + V   ++F+++ +W +E   +     P +    I GNK D+
Sbjct: 885  FRALAPMYYRGAAAAVIVYDVTRPRTFKSVKSWIQELRSFG----PPNIVLAIAGNKCDL 718

Query: 129  KE-RQVSTEEAQAWCKDNGDYPYFETSAKDSTNVAAAFEEAVRRILATEDRSEHLIQTDT 187
            +E R+V  ++AQ +        + ETSA  + NV   F E  R++   ED       ++T
Sbjct: 717  EELREVVEKDAQEYASSISAI-FGETSAMTAVNVEEMFTELARQLPPEEDNPHP---SNT 550

Query: 188  VNLHRKP 194
            VNL R+P
Sbjct: 549  VNLRRQP 529
>12339
          Length = 578

 Score =  124 bits (311), Expect = 2e-29,   Method: Compositional matrix adjust.
 Identities = 53/115 (46%), Positives = 76/115 (66%)
 Frame = -2

Query: 66  QERFRSLRTPFYRGSDCCLLTFSVDDSQSFQNLSNWKKEFIYYADVKEPESFPFVILGNK 125
           QERF+SL   FYRG+DCC+L + V + ++F +L +W++EF+  A  ++PE FPFV++GNK
Sbjct: 577 QERFQSLGVAFYRGADCCILVYDVTEXKTFDSLDSWQREFLNQASPRDPEHFPFVVIGNK 398

Query: 126 TDIKERQVSTEEAQAWCKDNGDYPYFETSAKDSTNVAAAFEEAVRRILATEDRSE 180
            D+  R V+ +  Q WC   G  PYFETSAK++ NV  AF+   +  LA E   E
Sbjct: 397 IDLDNRVVTAKRGQGWCSTKGGIPYFETSAKEAINVEQAFQTVAKNALAQESEVE 233
>34468
          Length = 1502

 Score =  108 bits (271), Expect = 1e-24,   Method: Compositional matrix adjust.
 Identities = 61/153 (39%), Positives = 89/153 (58%), Gaps = 2/153 (1%)
 Frame = +1

Query: 7   LFKIILLGDGGVGKSSLMNRYVTNKFDSQLFHTIGVEFLNKDLEVDGHFVTMQIWDTAGQ 66
           +FKII++GD  VGK+ L  R+   KF  +   TIGV+F  K ++VD   + +Q+WDTAGQ
Sbjct: 493 IFKIIVIGDSNVGKTCLTYRFCLGKFPDKTEATIGVDFREKSIQVDSEHLKLQLWDTAGQ 672

Query: 67  ERFR-SLRTPFYRGSDCCLLTFSVDDSQSFQNLSNWKKEFIYYADVKEPESFPFVILGNK 125
           ERFR S+   +YR     +  + +    SF+N+  W +E   +   K     P +++GNK
Sbjct: 673 ERFRKSMVQHYYRNVHAVVFVYDMTKMSSFENMPAWIEECDRHNLTK---YIPRILVGNK 843

Query: 126 TDIKER-QVSTEEAQAWCKDNGDYPYFETSAKD 157
            D+ ER  V+T  AQ +  D  + P FETSAKD
Sbjct: 844 CDVVERIAVNTNLAQKFA-DAHNMPLFETSAKD 939
>05468
          Length = 1558

 Score =  102 bits (254), Expect = 1e-22,   Method: Compositional matrix adjust.
 Identities = 62/182 (34%), Positives = 99/182 (54%), Gaps = 3/182 (1%)
 Frame = -3

Query: 4    KSSLFKIILLGDGGVGKSSLMNRYVTNKFDSQLFHTIGVEFLNKDLEVDGH-FVTMQIWD 62
            K  L+KI+++G+ G GK+S++ RYV   F      TIGV+F  K L  D    + +Q+WD
Sbjct: 1550 KEHLYKILVIGELGTGKTSIIKRYVHQFFSQHYRATIGVDFALKVLNWDADTLIRLQLWD 1371

Query: 63   TAGQERFRSLRTPFYRGSDCCLLTFSVDDSQSFQNLSNWKKEFIYYADVKEPESFPFVIL 122
             AGQERF ++   +Y+ +    + F V  + +F  ++ WK +      + +    P V+L
Sbjct: 1370 IAGQERFGNMTRVYYKEAVGAFVVFDVTRASTFDAVTKWKNDLDSKVQLADGSPVPCVLL 1191

Query: 123  GNKTD-IKERQV-STEEAQAWCKDNGDYPYFETSAKDSTNVAAAFEEAVRRILATEDRSE 180
             NK D  KE  V +T +   +C + G   ++ETSAK++ N+  A    V RIL  +DR+ 
Sbjct: 1190 ANKCDQAKEGLVNNTSQMDEFCSEKGFIGWYETSAKENINIDEAARFLVTRIL-EKDRAM 1014

Query: 181  HL 182
             L
Sbjct: 1013 QL 1008
>00552
          Length = 455

 Score = 98.6 bits (244), Expect = 2e-21,   Method: Compositional matrix adjust.
 Identities = 49/78 (62%), Positives = 57/78 (73%)
 Frame = -1

Query: 4   KSSLFKIILLGDGGVGKSSLMNRYVTNKFDSQLFHTIGVEFLNKDLEVDGHFVTMQIWDT 63
           KS L K++LLGDGGVGKSSLMNR+V+NKFD+Q FHTIGVEFL KD+ VDG   TMQ    
Sbjct: 455 KSRLLKVVLLGDGGVGKSSLMNRFVSNKFDAQSFHTIGVEFLTKDVVVDGETFTMQKPAR 276

Query: 64  AGQERFRSLRTPFYRGSD 81
             Q   R LR P  +GS+
Sbjct: 275 LAQLVRRQLRNPEVQGSN 222

 Score = 84.3 bits (207), Expect = 3e-17,   Method: Compositional matrix adjust.
 Identities = 36/49 (73%), Positives = 44/49 (89%)
 Frame = -3

Query: 60  IWDTAGQERFRSLRTPFYRGSDCCLLTFSVDDSQSFQNLSNWKKEFIYY 108
           IWDTAGQER++SLRTPFYRG+DCCLLTFSVD+ +S Q+LS+W  EF+ Y
Sbjct: 147 IWDTAGQERYKSLRTPFYRGTDCCLLTFSVDNLKSLQSLSDWYDEFVNY 1
>01972
          Length = 2359

 Score = 74.7 bits (182), Expect(2) = 3e-20,   Method: Compositional matrix adjust.
 Identities = 42/136 (30%), Positives = 67/136 (49%)
 Frame = +3

Query: 39  TIGVEFLNKDLEVDGHFVTMQIWDTAGQERFRSLRTPFYRGSDCCLLTFSVDDSQSFQNL 98
           T+GVE            +   +WDTAGQE+F  LR  +Y    C ++ F V    +++N+
Sbjct: 396 TLGVEVHPLLFHTSRGKLKFNVWDTAGQEKFGGLRDGYYIQGQCAVIMFDVTSRVTYKNV 575

Query: 99  SNWKKEFIYYADVKEPESFPFVILGNKTDIKERQVSTEEAQAWCKDNGDYPYFETSAKDS 158
            NW ++      V+  E+ P V+ GNK DIK+R+V  +      K N    Y++ SAK +
Sbjct: 576 PNWHRDL-----VRVCENIPIVLCGNKVDIKDRKVKAKAIVFHRKKN--LQYYDISAKSN 734

Query: 159 TNVAAAFEEAVRRILA 174
            N    F    R+++ 
Sbjct: 735 YNFEKPFLWLARKLVG 782

 Score = 40.4 bits (93), Expect(2) = 3e-20,   Method: Compositional matrix adjust.
 Identities = 14/30 (46%), Positives = 24/30 (80%)
 Frame = +1

Query: 8   FKIILLGDGGVGKSSLMNRYVTNKFDSQLF 37
           FK++L+GDGGVGK++ + R+VT +F+  + 
Sbjct: 304 FKLVLVGDGGVGKTTFVKRHVTGEFEKNML 393
>07465
          Length = 1103

 Score = 94.4 bits (233), Expect = 3e-20,   Method: Compositional matrix adjust.
 Identities = 64/173 (36%), Positives = 88/173 (50%), Gaps = 3/173 (1%)
 Frame = +3

Query: 21  SSLMNRYVTNKFDSQLFHTIGVEFLNKDLEVDGHFVTMQIWDTAGQERFRSLRTPFYRGS 80
           SS++ RY    F      TIGV+FL + +EV G  V + +WDTAGQE F ++   +YRG+
Sbjct: 240 SSMIQRYCKGIFTKDYKKTIGVDFLERQIEVGGEDVRLMLWDTAGQEEFDAITKAYYRGA 419

Query: 81  DCCLLTFSVDDSQSFQNLSNWKKEFIYYADVKEPESFPFVILGNKTD-IKERQVSTEEAQ 139
             C+L FS  D  SF+ L  WK++        E      VI+ NK D I +  V  EEA+
Sbjct: 420 QACVLAFSTVDRDSFEALETWKRKV-----EDEVGEIGMVIVQNKIDLIDDAVVRPEEAE 584

Query: 140 AWCKDNGDYPYFETSAKDSTNVAAAFEEAVRRILATEDRSEHLIQT--DTVNL 190
              K      ++ TS K++ NV   F     R LA  D+  H + T  D VNL
Sbjct: 585 NLAK-KLRLRFYRTSVKENMNVDEVF-----RYLA--DKYLHQLNTGMDEVNL 719
>33374
          Length = 489

 Score = 75.1 bits (183), Expect(2) = 5e-20,   Method: Compositional matrix adjust.
 Identities = 42/122 (34%), Positives = 68/122 (55%), Gaps = 4/122 (3%)
 Frame = +1

Query: 44  FLNKDLEVDGHFVTMQIWDTAGQERFRSLRTPFYRGSDCCLLTFSVDDSQSFQNLSNWKK 103
           FL + + +D   V  +IWDTAGQER+ SL   +YRG+   ++ + + +  +F     W K
Sbjct: 139 FLTQTVCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNQDTFGRAKTWVK 318

Query: 104 EFIYYADVKEPESFPFVIL---GNKTDI-KERQVSTEEAQAWCKDNGDYPYFETSAKDST 159
           E        + ++ P +++   GNK D+  +R V  EEAQA+ ++N    + ETSAK + 
Sbjct: 319 EL-------QRQASPNIVIALAGNKADLANKRMVEFEEAQAYAEENS-LLFMETSAKTAM 474

Query: 160 NV 161
           NV
Sbjct: 475 NV 480

 Score = 38.9 bits (89), Expect(2) = 5e-20,   Method: Compositional matrix adjust.
 Identities = 20/42 (47%), Positives = 26/42 (61%)
 Frame = +2

Query: 3  GKSSLFKIILLGDGGVGKSSLMNRYVTNKFDSQLFHTIGVEF 44
          GK   FK++LLG+  VGKSSL+ R+V  +F      TIG  F
Sbjct: 17 GKICQFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAF 142
>26083
          Length = 432

 Score = 86.7 bits (213), Expect = 6e-18,   Method: Compositional matrix adjust.
 Identities = 43/120 (35%), Positives = 71/120 (59%), Gaps = 2/120 (1%)
 Frame = +1

Query: 8   FKIILLGDGGVGKSSLMNRYVTNKFDSQLFHTIGVEFLNKDLEVDGHFVTMQIWDTAGQE 67
           FK++ LG+  VGK+SL+ R++ + FD+    TIG++FL+K + ++   + +Q+WDTAGQE
Sbjct: 79  FKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTIRLQLWDTAGQE 258

Query: 68  RFRSLRTPFYRGSDCCLLTFSVDDSQSFQNLSNWKKEFIYYADVKEPESFPFVIL--GNK 125
           RFRSL   + R S   ++ + + ++ SF   S W        DV+       +I+  GNK
Sbjct: 259 RFRSLIPSYIRDSSVAVVVYDITNANSFHQTSKWID------DVRTERGSDVIIMLVGNK 420
>07580
          Length = 921

 Score = 71.6 bits (174), Expect(2) = 2e-16,   Method: Compositional matrix adjust.
 Identities = 40/127 (31%), Positives = 70/127 (55%), Gaps = 1/127 (0%)
 Frame = +3

Query: 47  KDLEVDGHFVTMQIWDTAGQERFRSLRTPFYRGSDCCLLTFSVDDSQSFQNLSNWKKEFI 106
           K +EVDG    ++I DTAG E+F ++R  + +     LL +S+    +F +L   +++ +
Sbjct: 177 KQVEVDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFLLAYSITAQSTFNDLQELREQIL 356

Query: 107 YYADVKEPESFPFVILGNKTDIK-ERQVSTEEAQAWCKDNGDYPYFETSAKDSTNVAAAF 165
               VK+ +  P +++GNK D++ ER V  ++ Q   + +    + ETSAK   NV   F
Sbjct: 357 R---VKDTDDVPMLLVGNKCDLEDERVVGKDQGQGLAR-SFSCAFLETSAKARINVNEIF 524

Query: 166 EEAVRRI 172
            + VR+I
Sbjct: 525 MDLVRQI 545

 Score = 30.4 bits (67), Expect(2) = 2e-16,   Method: Compositional matrix adjust.
 Identities = 12/25 (48%), Positives = 19/25 (76%)
 Frame = +2

Query: 8  FKIILLGDGGVGKSSLMNRYVTNKF 32
          +K+++LG GGVGKS+L  ++V   F
Sbjct: 62 YKLVVLGSGGVGKSALTVQFVQGDF 136
>13901
          Length = 962

 Score = 77.8 bits (190), Expect = 3e-15,   Method: Compositional matrix adjust.
 Identities = 37/96 (38%), Positives = 57/96 (59%), Gaps = 1/96 (1%)
 Frame = -3

Query: 7   LFKIILLGDGGVGKSSLMNRYVTNKFDSQLFHTIGVEFLNKDLE-VDGHFVTMQIWDTAG 65
           LFK+I++GD  VGK+S + RYV + F      TIGV+F  K +   D   + +Q+WD AG
Sbjct: 288 LFKVIIIGDPTVGKTSFVQRYVNDSFRRDYKMTIGVDFALKVIRWSDKCNIKLQLWDIAG 109

Query: 66  QERFRSLRTPFYRGSDCCLLTFSVDDSQSFQNLSNW 101
           QERF S+   +Y+ +  C++ F +    ++QN   W
Sbjct: 108 QERFTSMTRVYYKDAHACIVMFDLTQKNTYQNAIRW 1
>11728
          Length = 635

 Score = 77.0 bits (188), Expect = 4e-15,   Method: Compositional matrix adjust.
 Identities = 48/162 (29%), Positives = 81/162 (50%), Gaps = 14/162 (8%)
 Frame = -1

Query: 8   FKIILLGDGGVGKSSLMNRYVTNKFDSQLFHTIGVEFLNKDLEVDGHFVTMQIWDTAGQE 67
            K +++GDG VGK+ L+  Y TN F  +   T+  +  + ++ VD   + + +WDTAGQE
Sbjct: 488 IKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTV-FDNYSANVMVDSKPINLGLWDTAGQE 312

Query: 68  RFRSLRTPFYRGSDCCLLTFSVDDSQSFQNL-SNWKKEFIYYADVKEPESFPFVILGNKT 126
            +  LR   Y  +D  L+ FS+    SF+N+ + W  E  ++       + P +++G K 
Sbjct: 311 DYDRLRPLSYPQTDVFLICFSLISPASFENVKAKWYPEVSHHC-----PNTPIILVGTKL 147

Query: 127 DIKERQVSTEEAQ-------------AWCKDNGDYPYFETSA 155
           D++E + + E+ +             A  KD G   Y E SA
Sbjct: 146 DLREDKETIEKLKEKKLAPITYPQGLAMAKDIGAGKYLECSA 21
>34359
          Length = 1042

 Score = 77.0 bits (188), Expect = 5e-15,   Method: Compositional matrix adjust.
 Identities = 40/129 (31%), Positives = 68/129 (52%)
 Frame = +3

Query: 8   FKIILLGDGGVGKSSLMNRYVTNKFDSQLFHTIGVEFLNKDLEVDGHFVTMQIWDTAGQE 67
           FK++L+G      ++++ R+VT     +   T+GVE            +   +WDTAGQE
Sbjct: 54  FKLVLVGGRWEWANNIVKRHVTGS*K-KYVATLGVEVHPLQFNTSRGLLRFNVWDTAGQE 230

Query: 68  RFRSLRTPFYRGSDCCLLTFSVDDSQSFQNLSNWKKEFIYYADVKEPESFPFVILGNKTD 127
           +F  LR  +Y    C ++ F V    +++N+ NW ++      V+  E+ P V+ GNK D
Sbjct: 231 KFGGLRDGYYIQGTCAIIMFDVTSRVTYKNVPNWHRDL-----VRVCENIPIVLCGNKVD 395

Query: 128 IKERQVSTE 136
           IK+R+V  +
Sbjct: 396 IKDRKVKAK 422
>13750
          Length = 503

 Score = 76.3 bits (186), Expect = 9e-15,   Method: Compositional matrix adjust.
 Identities = 62/175 (35%), Positives = 88/175 (50%), Gaps = 6/175 (3%)
 Frame = -2

Query: 20  KSSLMNRYVTNKFDSQLFHTIGV---EFLNKDLEVDGHFVTMQIWDTAGQERFRSLRTPF 76
           K+ L+ RY    F  +   TI V   EF   +   D   V   +WDT G E +RSL    
Sbjct: 502 KTCLLRRYQKGFFMDRTMPTIAVLCSEF--NESRTDPLNVRYTLWDTGGAETYRSLWVSH 329

Query: 77  YRGSDCCLLTFSVDDSQSFQNLSN-WKKEFIYYADVKEPESFPFVILGNKTDIKE-RQVS 134
           +RG+   LL + V    SF   +  W+K  +   ++ E +    + +G+KTD++E R +S
Sbjct: 328 FRGAQVALLVYDVTCEWSFLTATTVWRKALM--KNIPEAQ---VIFVGSKTDLEENRVIS 164

Query: 135 TEEAQAWCKDNGDYPYFETSAKDSTNVAAAFEEAVRRILATEDRSEHL-IQTDTV 188
           TE  QA+    G Y +FETS+    NV A F E +  ILA   RS HL +  DTV
Sbjct: 163 TERGQAFATQCG-YTFFETSSVTGKNVDAVFWE-IAFILARLQRSAHLELSMDTV 5
>19006
          Length = 568

 Score = 75.9 bits (185), Expect = 1e-14,   Method: Compositional matrix adjust.
 Identities = 38/122 (31%), Positives = 67/122 (54%), Gaps = 1/122 (0%)
 Frame = -2

Query: 9   KIILLGDGGVGKSSLMNRYVTNKFDSQLFHTIGVEFLNKDLEVDGHFVTMQIWDTAGQER 68
           K++++GDG  GK+ L+  +  ++F      T+   ++  D+EVD   V + +WDTAGQE 
Sbjct: 432 KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYV-ADIEVDSKQVELALWDTAGQED 256

Query: 69  FRSLRTPFYRGSDCCLLTFSVDDSQSFQNLS-NWKKEFIYYADVKEPESFPFVILGNKTD 127
           +  LR   Y  +D  L+ FS+D   S +N+   W  E  ++       + P +++GNK D
Sbjct: 255 YDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVRHFC-----PNVPIILVGNKKD 91

Query: 128 IK 129
           ++
Sbjct: 90  LR 85
>35581
          Length = 364

 Score = 75.5 bits (184), Expect = 1e-14,   Method: Compositional matrix adjust.
 Identities = 38/95 (40%), Positives = 55/95 (57%), Gaps = 1/95 (1%)
 Frame = +2

Query: 8   FKIILLGDGGVGKSSLMNRYVTNKF-DSQLFHTIGVEFLNKDLEVDGHFVTMQIWDTAGQ 66
           FK +LLGD GVGK+ L+NR  T+KF DS L        L       G   ++ +WDTAGQ
Sbjct: 47  FKCVLLGDAGVGKTCLLNRLATDKFLDSPLTSLTTASLLTTVTLTSGVMASVDLWDTAGQ 226

Query: 67  ERFRSLRTPFYRGSDCCLLTFSVDDSQSFQNLSNW 101
           ER+RSL + +YR +   L+ +   D++    L++W
Sbjct: 227 ERYRSLTSSYYRDTKAVLIVY---DAEHKLKLTDW 322
>19656
          Length = 428

 Score = 71.6 bits (174), Expect = 2e-13,   Method: Compositional matrix adjust.
 Identities = 38/98 (38%), Positives = 56/98 (57%), Gaps = 1/98 (1%)
 Frame = +3

Query: 8   FKIILLGDGGVGKSSLMNRYVTNKFDSQLFHTIGVEFLNKDLEVDGHFVTMQIWDTAGQE 67
            K +++GDG VGK+ L+  Y TN F  +   T+  +  + ++ VDG  V + +WDTAGQE
Sbjct: 114 IKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTV-FDNYSANVMVDGRPVNLGLWDTAGQE 290

Query: 68  RFRSLRTPFYRGSDCCLLTFSVDDSQSFQNL-SNWKKE 104
            +  LR   Y  +D  LL FSV    SF+N+ + W  E
Sbjct: 291 DYDRLRPLSYPQTDVFLLCFSVASPASFENIRAKWYPE 404
>19046
          Length = 445

 Score = 70.9 bits (172), Expect = 4e-13,   Method: Compositional matrix adjust.
 Identities = 43/111 (38%), Positives = 64/111 (57%), Gaps = 2/111 (1%)
 Frame = -2

Query: 66  QERFRSLRTPFYRGSDCCLLTFSVDDSQSFQNLSNWKKEFIYYADVKEPESFPFVILGNK 125
           QE F ++R  + R  D  LL FSV D +SF+N++N+  + +    VK+ +S+P ++  NK
Sbjct: 444 QEEFSAMREQYMRKGDGFLLVFSVTDFRSFENMANFHTQILR---VKDRDSYPMILCANK 274

Query: 126 TD-IKERQVSTEEAQAWCKDNGDYPYFETSAKDST-NVAAAFEEAVRRILA 174
            D + +R+VS E+ +         PY ETSAKD   NV  AF + VR I A
Sbjct: 273 VDLVHQRKVSEEQVRDLAT-RLRIPYIETSAKDPPLNVDLAFHQVVRVIRA 124
>24619
          Length = 509

 Score = 70.9 bits (172), Expect = 4e-13,   Method: Compositional matrix adjust.
 Identities = 43/111 (38%), Positives = 63/111 (56%), Gaps = 2/111 (1%)
 Frame = -2

Query: 66  QERFRSLRTPFYRGSDCCLLTFSVDDSQSFQNLSNWKKEFIYYADVKEPESFPFVILGNK 125
           QE F ++R  + R  D  LL FSV D QSF+N+ N+  + +    VK+ +++P ++  NK
Sbjct: 508 QEEFSAMREQYMRKGDGFLLVFSVIDYQSFENMVNFHTQIL---RVKDRDTYPMILCANK 338

Query: 126 TD-IKERQVSTEEAQAWCKDNGDYPYFETSAKDST-NVAAAFEEAVRRILA 174
            D + +R+VS E+ +         PY ETSAKD   NV  AF + VR I A
Sbjct: 337 VDLVHQRKVSEEQVRDLAT-RLRIPYIETSAKDPPLNVDLAFHQVVRVIRA 188
>00858
          Length = 1658

 Score = 66.6 bits (161), Expect = 6e-12,   Method: Compositional matrix adjust.
 Identities = 40/126 (31%), Positives = 65/126 (51%)
 Frame = -2

Query: 47   KDLEVDGHFVTMQIWDTAGQERFRSLRTPFYRGSDCCLLTFSVDDSQSFQNLSNWKKEFI 106
            K + +DG    + I DTAGQE   ++R    R  +  L  F+V + +SF++++ ++++  
Sbjct: 1474 KQVVIDGETCLLDILDTAGQEEXSAMRDQCMRTGEGFLCVFAVXNLKSFEDINQYREQI- 1298

Query: 107  YYADVKEPESFPFVILGNKTDIKERQVSTEEAQAWCKDNGDYPYFETSAKDSTNVAAAFE 166
                VK+ +  P V++GNK D+  R V   + +    +    PY ETSAK    V  AF 
Sbjct: 1297 --KRVKDADEVPMVLVGNKVDLPIRNVEQRQGKHMA-ELYHIPYVETSAKTRQGVDDAFY 1127

Query: 167  EAVRRI 172
              VR I
Sbjct: 1126 TLVREI 1109
>30760
          Length = 596

 Score = 65.5 bits (158), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 51/162 (31%), Positives = 77/162 (47%), Gaps = 5/162 (3%)
 Frame = -1

Query: 9   KIILLGDGGVGKSSLMNRYVTNK--FDSQLFHTIGVEFLNKDLEVDGHF--VTMQIWDTA 64
           K I+ GD GVGKSS+   + ++   F      T GVE L K + +      V + ++D+A
Sbjct: 524 KCIVTGDSGVGKSSICQVFHSDSAHFPKNYSMTTGVEVLVKLVNIPDSRDQVELYLFDSA 345

Query: 65  GQERFRSLRTPFYRGSDCCLLTFSVDDSQSFQNLSNWKKEFIYYADVKEPESFPFVILGN 124
           G+E F    T F+      ++ + V D  SF     W +        K     P V++ N
Sbjct: 344 GKEIFSENVTKFWDQPSVVMVVYDVTDETSFSGCVRWLERV---RAAKPNTVIPGVLVAN 174

Query: 125 KTDIKE-RQVSTEEAQAWCKDNGDYPYFETSAKDSTNVAAAF 165
           KTD+ E R+VS +E +   + +G   YFE SAK+  N    F
Sbjct: 173 KTDLDERRRVSRKEGKDLAQSHG-LEYFECSAKEMQNTDTPF 51
>01398
          Length = 1421

 Score = 62.8 bits (151), Expect = 9e-11,   Method: Compositional matrix adjust.
 Identities = 34/106 (32%), Positives = 59/106 (55%), Gaps = 1/106 (0%)
 Frame = -2

Query: 66   QERFRSLRTPFYRGSDCCLLTFSVDDSQSFQNLSNWKKEFIYYADVKEPESFPFVILGNK 125
            QERFRS+   +YR S   ++ + +    +F+NL  W +E   +    EP    F++LG+K
Sbjct: 1420 QERFRSITRSYYRNSVGVIIVYDITKRSTFENLKQWYEEARNHI---EPHKAIFLVLGHK 1250

Query: 126  TDIKE-RQVSTEEAQAWCKDNGDYPYFETSAKDSTNVAAAFEEAVR 170
            +D ++ RQV+  E + + + +G   +FETSAK   N+   F +  +
Sbjct: 1249 SDREDARQVTAREGRRFAEMHG-LKFFETSAKSGHNIEDVFAQIAK 1115
>31291
          Length = 446

 Score = 62.0 bits (149), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 47/150 (31%), Positives = 71/150 (47%), Gaps = 14/150 (9%)
 Frame = -1

Query: 58  MQIWDTAGQERFRSLRTPFYRGSDCCLLTFSVDDSQSFQNLS-NWKKEFIYYADVKEPES 116
           +Q+WDTAGQE +  LR   Y  +D  +L FS+    S +N+   W  E  ++    +P  
Sbjct: 446 LQLWDTAGQEDYDRLRPLAYPNTDVFMLXFSLMSEASMKNVKVKWYPEIRHH----DPH- 282

Query: 117 FPFVILGNKTDIKE-----------RQ--VSTEEAQAWCKDNGDYPYFETSAKDSTNVAA 163
            P V++G K D+++           RQ  VS+ +     K      YFE S+K   N+  
Sbjct: 281 VPIVLVGTKLDLRQDKEAVRKLRSSRQDPVSSNQGNDLAKAIKAKRYFECSSKTQENLKT 102

Query: 164 AFEEAVRRILATEDRSEHLIQTDTVNLHRK 193
           AFEE VR  L  + ++    +   V L RK
Sbjct: 101 AFEETVRVALNMDGQNNKRPKPKCVLL*RK 12
>26536
          Length = 829

 Score = 61.6 bits (148), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 41/118 (34%), Positives = 61/118 (51%), Gaps = 1/118 (0%)
 Frame = +2

Query: 56  VTMQIWDTAGQERFRSLRTPFYRGSDCCLLTFSVDDSQSFQNLSNWKKEFIYYADVKEPE 115
           V+    DTAGQE + S+R  + R  D  ++ +SV D  SFQ     +  F +    ++  
Sbjct: 128 VSWTFLDTAGQEEYSSMREHYTRSGDGFIVVYSVTDVTSFQEA---EAVFRWLTRFQDET 298

Query: 116 SFPFVILGNKTDI-KERQVSTEEAQAWCKDNGDYPYFETSAKDSTNVAAAFEEAVRRI 172
           S   V+ GNKTD+  +R+V+ EE +    D     YFETSAK   NV+  +   +R I
Sbjct: 299 SIHAVLCGNKTDLTSDRKVTPEEGRKMA-DRLGMLYFETSAKTGDNVSQVYHGLLRSI 469

 Score = 34.7 bits (78), Expect = 0.024,   Method: Compositional matrix adjust.
 Identities = 14/25 (56%), Positives = 19/25 (76%)
 Frame = +2

Query: 8   FKIILLGDGGVGKSSLMNRYVTNKF 32
           +KI++LG GGVGKSSL  R+  + F
Sbjct: 488 YKIVMLGSGGVGKSSLTIRFTQDTF 562
>33380
          Length = 282

 Score = 61.6 bits (148), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 28/78 (35%), Positives = 50/78 (64%)
 Frame = +3

Query: 56  VTMQIWDTAGQERFRSLRTPFYRGSDCCLLTFSVDDSQSFQNLSNWKKEFIYYADVKEPE 115
           V +QIWDTAGQER+R++ T +YRG+   +L + V + +SF  + +W  +   Y+     +
Sbjct: 60  VKLQIWDTAGQERYRTITTAYYRGAMGFILMYDVTNEESFNAVQDWCTQIKTYS----WD 227

Query: 116 SFPFVILGNKTDIKERQV 133
           +   V++GNK D+++ +V
Sbjct: 228 NAQVVLVGNKCDLEDERV 281
>10708
          Length = 2775

 Score = 42.7 bits (99), Expect(2) = 1e-09,   Method: Compositional matrix adjust.
 Identities = 18/43 (41%), Positives = 26/43 (60%)
 Frame = -2

Query: 56   VTMQIWDTAGQERFRSLRTPFYRGSDCCLLTFSVDDSQSFQNL 98
            V + +WDTAGQE +  LR   Y  +D  L+ FS+D   S +N+
Sbjct: 2723 VELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENI 2595

 Score = 36.2 bits (82), Expect(2) = 1e-09,   Method: Compositional matrix adjust.
 Identities = 25/97 (25%), Positives = 40/97 (41%), Gaps = 13/97 (13%)
 Frame = -3

Query: 97   NLSNWKKEFIYYADVKEPESFPFVILGNKTDI-------------KERQVSTEEAQAWCK 143
            +L  W  E  ++       + P +++GNK D+             K+  V  +E +A  +
Sbjct: 2596 SLKKWTPEVRHFCP-----NVPIILVGNKKDLRNDENTKRELMKMKQEPVRLDEGRAMSE 2432

Query: 144  DNGDYPYFETSAKDSTNVAAAFEEAVRRILATEDRSE 180
                Y Y E SAK    V   FE A R  L T+ + +
Sbjct: 2431 KINAYSYLECSAKTKEGVREVFETATRAALQTKKKKK 2321
>27191
          Length = 443

 Score = 54.7 bits (130), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 31/107 (28%), Positives = 56/107 (52%)
 Frame = +1

Query: 20  KSSLMNRYVTNKFDSQLFHTIGVEFLNKDLEVDGHFVTMQIWDTAGQERFRSLRTPFYRG 79
           K+ L+  +  +KF+     T+GV++  K   V+G  + + +WD +G   +  +R   Y G
Sbjct: 1   KTCLIKHFCESKFNQGYQPTVGVDYGFKIQTVNGVDMRVHMWDLSGSNEYLDVRNELYTG 180

Query: 80  SDCCLLTFSVDDSQSFQNLSNWKKEFIYYADVKEPESFPFVILGNKT 126
           SD   + F V ++ SF+ L +W +E   +A    P +   VI+GN+ 
Sbjct: 181 SDAIFIVFDVSNTPSFEALDSWLREINRFA-TGSPLN---VIVGNRV 309
>32723
          Length = 384

 Score = 53.5 bits (127), Expect = 6e-08,   Method: Compositional matrix adjust.
 Identities = 33/101 (32%), Positives = 54/101 (53%), Gaps = 1/101 (0%)
 Frame = +2

Query: 66  QERFRSLRTPFYRGSDCCLLTFSVDDSQSFQNLSNWKKEFIYYADVKEPESFPFVILGNK 125
           QERFRS+   +YR ++  +L + V   QS+++L  W  E   YA  K      F++ GNK
Sbjct: 2   QERFRSITQSYYRSANALILVYDVCSQQSYESLPQWIHEIELYAGTK---VLAFLV-GNK 169

Query: 126 TD-IKERQVSTEEAQAWCKDNGDYPYFETSAKDSTNVAAAF 165
            D   +R++ T   + +  +  +  + ETSAK++ NV   F
Sbjct: 170 IDQTDKREIPTHIGKEFA-ERYEMRFLETSAKEADNVEKLF 289
>14775
          Length = 380

 Score = 43.9 bits (102), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 49/173 (28%), Positives = 64/173 (36%), Gaps = 4/173 (2%)
 Frame = -2

Query: 20  KSSLMNRYVTNKFDSQLFHTIGV---EFLNKDLEVDGHFVTMQIWDTAGQERFRSLRTPF 76
           K+ L+ RY    F  +   TI V   EF   +   D   V   +WDT G E +RSL    
Sbjct: 379 KTCLLRRYQKGFFMDRTMPTIAVLCSEF--NESRTDPLNVRYTLWDTGGAETYRSLWVSH 206

Query: 77  YRGSDCCLLTFSVDDSQSFQNLSNWKKEFIYYADVKEPESFPFVILGNKTDIKERQVSTE 136
           +RG+   LL +                                             V+ E
Sbjct: 205 FRGAQVALLVY--------------------------------------------DVTCE 158

Query: 137 EAQAWCKDNGDYPYFETSAKDSTNVAAAFEEAVRRILATEDRSEHL-IQTDTV 188
             QA+    G Y +FETS+    NV A F E +  ILA   RS HL +  DTV
Sbjct: 157 RGQAFATQCG-YTFFETSSVTGKNVDAVFWE-IAFILARLQRSAHLELSMDTV 5
>17872
          Length = 700

 Score = 42.0 bits (97), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 38/127 (29%), Positives = 52/127 (40%), Gaps = 14/127 (11%)
 Frame = -1

Query: 66  QERFRSLRTPFYRGSDCCLLTFSVDDSQSFQN-LSNWKKEFIYYADVKEPESFPFVILGN 124
           Q+ F SLR   Y  ++  LL FSV    SF N +  W  E  Y+         P V++G 
Sbjct: 700 QDDFDSLRPLCYPETNVFLLCFSVVSPTSFHNVMEKWVPELRYHC-----PGAPLVVVGT 536

Query: 125 KTDI-------------KERQVSTEEAQAWCKDNGDYPYFETSAKDSTNVAAAFEEAVRR 171
           ++D+             KE+ VS EEA       G   Y E SA    N+   F+  +  
Sbjct: 535 QSDLRNDVKVLIELAKYKEKPVSEEEAVKMADQLGAQ-YVECSALTQKNLKEVFDTGILA 359

Query: 172 ILATEDR 178
            L   DR
Sbjct: 358 SLNWTDR 338
>31932
          Length = 437

 Score = 41.6 bits (96), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 21/70 (30%), Positives = 38/70 (54%), Gaps = 2/70 (2%)
 Frame = -1

Query: 107 YYADVKEP--ESFPFVILGNKTDIKERQVSTEEAQAWCKDNGDYPYFETSAKDSTNVAAA 164
           + A V  P   + P ++LGNK+D+  R+V  +E +  CK++    + ETS KD T +  +
Sbjct: 437 WTASVNWPYGSTVPCLLLGNKSDLGHREVEQDEIEDLCKEHDFLGWSETSVKDGTMIDES 258

Query: 165 FEEAVRRILA 174
               +  ++A
Sbjct: 257 MNYLIEEMMA 228
>18509
          Length = 625

 Score = 40.4 bits (93), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 24/70 (34%), Positives = 35/70 (50%)
 Frame = -3

Query: 111 VKEPESFPFVILGNKTDIKERQVSTEEAQAWCKDNGDYPYFETSAKDSTNVAAAFEEAVR 170
           VK+ +  P V++GNK D+  R V   + +    +    PY ETSAK    V  AF   VR
Sbjct: 545 VKDADEVPMVLVGNKVDLPIRNVEQRQGKHMA-ELYHIPYVETSAKTRQGVDDAFYTLVR 369

Query: 171 RILATEDRSE 180
            I   ++R +
Sbjct: 368 EIRKYKERKD 339
>01095
          Length = 1745

 Score = 38.5 bits (88), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 31/120 (25%), Positives = 52/120 (43%), Gaps = 3/120 (2%)
 Frame = -1

Query: 85   LTFSVDDSQSFQNLSNWKKEFIYYADVKEPESFPFVILGNKTDI-KERQVSTEEAQAWCK 143
            + + + +  +F     W KE    A      +    + GNK D+  +R V  EEAQA+ +
Sbjct: 1745 VVYDITNQDTFGRAKTWVKELQRQAS----PNIVIALAGNKADLANKRMVEFEEAQAYAE 1578

Query: 144  DNGDYPYFETSAKDSTNVAAAFEEAVRRILATE--DRSEHLIQTDTVNLHRKPKPNSSCC 201
            +N    + ETSAK + NV   F    +++   E    S+   Q   +N  +  +    CC
Sbjct: 1577 EN-SLLFMETSAKTAMNVNDIFLAIAKKLPKNEGGGGSQPRQQGVRLNNEQSQQSEGGCC 1401
>09827
          Length = 1201

 Score = 33.9 bits (76), Expect = 0.041,   Method: Compositional matrix adjust.
 Identities = 25/140 (17%), Positives = 59/140 (42%), Gaps = 4/140 (2%)
 Frame = -3

Query: 1    MAGKSSLFKIILLGDGGVGKSSLMNRYVTNKFDSQL----FHTIGVEFLNKDLEVDGHFV 56
            M GK  + +I+++G    GK++++ +    +  + +    F+   VE+ N         +
Sbjct: 1130 MFGKKDM-RILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKN---------I 981

Query: 57   TMQIWDTAGQERFRSLRTPFYRGSDCCLLTFSVDDSQSFQNLSNWKKEFIYYADVKEPES 116
            +  +WD  GQ++ R L   +++ +   +     +D +  Q     ++E     +  E   
Sbjct: 980  SFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDKERVQEA---REELTRMLNEDELRD 810

Query: 117  FPFVILGNKTDIKERQVSTE 136
               ++  NK D+     + E
Sbjct: 809  AVLLVFANKQDLPHAMATAE 750
>08153
          Length = 1703

 Score = 32.7 bits (73), Expect = 0.094,   Method: Compositional matrix adjust.
 Identities = 35/178 (19%), Positives = 70/178 (39%), Gaps = 28/178 (15%)
 Frame = +1

Query: 1   MAGKSSLFK---------IILLGDGGVGKSSLMNRYVTNKFDSQL----FHTIGVEFLNK 47
           M G  SLFK         I+++G    GK++++ +    +  + +    F+   VE+ N 
Sbjct: 37  MGGFVSLFKNLFGKKEVRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKN- 213

Query: 48  DLEVDGHFVTMQIWDTAGQERFRSLRTPFYRGSDCCLLTFSVDDSQSFQNLSNWKKEFIY 107
                   ++  +WD  GQ++ R L   +++ +   +    V DS   + ++  K+E   
Sbjct: 214 --------ISFTVWDVGGQDKIRPLWRHYFQNTQGLIF---VVDSNDRERINEAKEELAR 360

Query: 108 YADVKEPESFPFVILGNKTDIKERQVSTEEA---------------QAWCKDNGDYPY 150
             +  +      ++  NK D+     ++E                 QA C  +GD  Y
Sbjct: 361 MLNEDDLRDAIILVFANKQDLPNAYSASEVTAHLGLANLKGRKWYMQATCATSGDGMY 534
>33605
          Length = 888

 Score = 32.0 bits (71), Expect = 0.16,   Method: Compositional matrix adjust.
 Identities = 28/112 (25%), Positives = 52/112 (46%), Gaps = 8/112 (7%)
 Frame = +1

Query: 1   MAGKSSLFKIILLGDGGVGKSSLMNRYVTNKFDSQLFHTIGVEFLNKDLEVDGHFVTMQI 60
           M  K    ++++LG    GK++++ ++     D+ +  T+G  F  K LE  G    + +
Sbjct: 478 MKQKEKEVRLLMLGLDNAGKTTILKKFNGEDIDT-ISPTLG--FNIKTLEHRGF--KLNV 642

Query: 61  WDTAGQERFRSLRTPFYRGSDCCLLTFSVDDSQSFQ--------NLSNWKKE 104
           WD  GQ+  RS    ++  +D   L + VD +   +         +S WKK+
Sbjct: 643 WDVGGQQSLRSYWRNYFESTDG--LVWVVDSADRMRIADCKRDYKVSWWKKD 792
>06994
          Length = 429

 Score = 30.0 bits (66), Expect = 0.68,   Method: Compositional matrix adjust.
 Identities = 12/25 (48%), Positives = 19/25 (76%)
 Frame = +3

Query: 8  FKIILLGDGGVGKSSLMNRYVTNKF 32
          +K+++LG GGVGKS+L  ++V   F
Sbjct: 57 YKLVVLGSGGVGKSALTVQFVQGIF 131
>10862
          Length = 2896

 Score = 28.9 bits (63), Expect = 1.4,   Method: Compositional matrix adjust.
 Identities = 18/71 (25%), Positives = 32/71 (45%)
 Frame = -3

Query: 60   IWDTAGQERFRSLRTPFYRGSDCCLLTFSVDDSQSFQNLSNWKKEFIYYADVKEPESFPF 119
            +WD  GQ++ R L   +Y G+    L F VD +     +   ++E     + +E      
Sbjct: 2474 VWDVGGQDKIRPLWRHYYTGTQG--LIFVVDCADR-DRIDEARQELHRIINDREMRDAII 2304

Query: 120  VILGNKTDIKE 130
            +I  NK D+ +
Sbjct: 2303 LIFANKQDLPD 2271
>25796
          Length = 422

 Score = 28.1 bits (61), Expect = 2.3,   Method: Compositional matrix adjust.
 Identities = 9/22 (40%), Positives = 16/22 (72%)
 Frame = -1

Query: 7  LFKIILLGDGGVGKSSLMNRYV 28
          LFK +++G  G GKS L++ ++
Sbjct: 68 LFKFLIIGSAGSGKSCLLHHFI 3
>14677
          Length = 378

 Score = 28.1 bits (61), Expect = 2.4,   Method: Compositional matrix adjust.
 Identities = 13/31 (41%), Positives = 19/31 (61%)
 Frame = -3

Query: 4   KSSLFKIILLGDGGVGKSSLMNRYVTNKFDS 34
           K+S     +LG+ G+GKS+LM+      FDS
Sbjct: 349 KASASTFFVLGETGIGKSTLMDTLFNTNFDS 257
>09576
          Length = 2266

 Score = 27.3 bits (59), Expect = 3.9,   Method: Compositional matrix adjust.
 Identities = 14/54 (25%), Positives = 25/54 (46%), Gaps = 1/54 (1%)
 Frame = -2

Query: 6    SLFKIILLGDGGVGKSSLMNR-YVTNKFDSQLFHTIGVEFLNKDLEVDGHFVTM 58
            +L K +   +  +G  ++M   Y   K+D        VEFL ++L  D  F+ +
Sbjct: 1005 ALLKFVYTDEVQIGPETVMTTLYAAKKYDVPALERACVEFLKRNLSSDNAFMLL 844
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|13937355|ref|NP_058599.1| esterase
D/formylglutathione hydrolase [Mus musculus]
         (282 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

27390                                                                 263   6e-71
03536                                                                  28   3.4  
01162                                                                  28   3.4  
19310                                                                  28   5.1  
>27390
          Length = 703

 Score =  263 bits (672), Expect = 6e-71,   Method: Compositional matrix adjust.
 Identities = 116/178 (65%), Positives = 142/178 (79%)
 Frame = +1

Query: 105 FYVNATEDPWKANYRMYSYVTEELPQLINANFPVDPQRMSIFGHSMGGHGALICALKNPG 164
           FYV+AT++ WK NYRMYSY+T+ELP L+N+NFP  P + SIFGHSMGGHGALICA+KNPG
Sbjct: 1   FYVDATQEKWKNNYRMYSYITKELPALVNSNFPTLPGKQSIFGHSMGGHGALICAMKNPG 180

Query: 165 KYRSVSAFAPICNPVLCSWGKKAFSGYLGPDESKWKAYDATCLVKAYSGSQIDILIDQGK 224
            + SVSAFAPICNP  C WGKKAF GYLG + + W+ YDATCL+K Y+G  +  LIDQGK
Sbjct: 181 MFCSVSAFAPICNPTECPWGKKAFKGYLGDNPNTWEDYDATCLLKKYNGPPLQFLIDQGK 360

Query: 225 DDEFLSNGQLLPDNFIAACTEKKIPVVFRLQEGYDHSYYFIATFIADHIRHHAKYLNA 282
            D FL + QLLP+NFI  CT  K  +  R+Q+GYDHSY+FIA+F+ DHI+HHAK+L A
Sbjct: 361 GDNFLEDKQLLPENFIKECTSTKTQITLRMQDGYDHSYFFIASFVEDHIKHHAKFLKA 534
>03536
          Length = 1776

 Score = 28.5 bits (62), Expect = 3.4,   Method: Compositional matrix adjust.
 Identities = 14/35 (40%), Positives = 21/35 (60%)
 Frame = +3

Query: 30  MRFAVYLPPQAESGKCPALYWLSGLTCTEQNFISK 64
           +RF +YL   +ES + P L   S LT + + FI+K
Sbjct: 495 LRFLIYLFVNSESRQSPLLLCASPLTFSLKQFIAK 599
>01162
          Length = 1892

 Score = 28.5 bits (62), Expect = 3.4,   Method: Compositional matrix adjust.
 Identities = 14/35 (40%), Positives = 21/35 (60%)
 Frame = -3

Query: 30  MRFAVYLPPQAESGKCPALYWLSGLTCTEQNFISK 64
           +RF +YL   +ES + P L   S LT + + FI+K
Sbjct: 798 LRFLIYLFVNSESRQSPLLLCASPLTFSLKQFIAK 694
>19310
          Length = 784

 Score = 27.7 bits (60), Expect = 5.1,   Method: Compositional matrix adjust.
 Identities = 29/118 (24%), Positives = 49/118 (41%), Gaps = 5/118 (4%)
 Frame = -3

Query: 138 VDPQRMSIFGHSMGGHGALICALKNPGKYRSVSAFAPICNPVLCSWGKKAFSGYLGPDES 197
           VD  R++I G S GG+ AL+   + P  ++   A AP+ +  L   G      YL   + 
Sbjct: 413 VDLNRVAIHGWSYGGYLALMGLAQRPDVFKVAVAGAPVVSWKLYDTGYT--ERYLSLPQV 240

Query: 198 KWKAYDATCL---VKAYSGSQIDILIDQGKDDEFLSNGQL--LPDNFIAACTEKKIPV 250
               Y    +   +K +   +  +LI  G  DE +    +  L    + AC   ++ V
Sbjct: 239 NVTGYTKGSVLHYLKQFPDEENRLLIVHGLIDENVHFHHINKLVTALVKACKPHQLQV 66
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|160707956|ref|NP_033804.2| annexin A7 [Mus musculus]
         (463 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

32521                                                                 264   7e-71
36934                                                                 161   4e-40
06659                                                                 159   3e-39
22178                                                                 101   1e-30
17882                                                                  76   1e-23
12136                                                                  91   9e-19
13827                                                                  72   4e-15
29756                                                                  64   9e-11
>32521
          Length = 1241

 Score =  264 bits (674), Expect = 7e-71,   Method: Compositional matrix adjust.
 Identities = 124/271 (45%), Positives = 188/271 (69%)
 Frame = +2

Query: 193 DQRQQIKAAFKTMYGKDLIKDLKSELSGNMEELILALFMPSTYYDAWSLRKAMQGAGTQE 252
           +QR++I   +KTM+GKDL K+L  ELSGN + L + + +    +DA  + KA++G GT E
Sbjct: 2   EQRREINLTYKTMFGKDLGKELSGELSGNFKTLCVEMLLGPAEFDAKQINKAVKGLGTDE 181

Query: 253 RVLIEILCTRTNQEIRDIVRCYQLEFGRDLEKDIRSDTSGHFERLLVSMCQGNRDERQSV 312
           R LIEI+CTRTN ++  +   Y+  + +D+E DI  DTSG F+RLL+   Q NR E Q  
Sbjct: 182 RALIEIICTRTNAQLTAMKEAYKTMYQKDVETDIEGDTSGPFKRLLIGCLQANRPEGQEF 361

Query: 313 NHQMAQEDAQRLYQAGEGRLGTDESCFNMILATRSFPQLKATMEAYSRMANRDLLSSVSR 372
           +   A++DAQ L +AGE + GTDES FN+++ +RSFPQL+AT + Y+++AN+D+  S+S 
Sbjct: 362 DRNKAKQDAQALLEAGEKKWGTDESRFNVVIVSRSFPQLRATFQEYAKLANKDIEDSISS 541

Query: 373 EFSGYVESGLKTILQCALNRPAFFAERLYYSMKGAGTDDSTLVRIVVTRSEIDLVQIKQM 432
           E SG  ++G+ T+++   ++   FA  L+ +MKG GTDD TLVR+V +R E+D+VQIK+ 
Sbjct: 542 EMSGDXKNGMLTVVRVIRSKATHFATELHRAMKGLGTDDDTLVRVVASRCEVDMVQIKEE 721

Query: 433 FTQMYQKTLSTMIASDTSGDYRKLLLAIVGQ 463
           F + +++TL + I  DTSGDYR +L  ++GQ
Sbjct: 722 FQRNFKQTLYSFIVDDTSGDYRLMLCNLIGQ 814

 Score = 75.5 bits (184), Expect = 4e-14,   Method: Compositional matrix adjust.
 Identities = 60/224 (26%), Positives = 111/224 (49%), Gaps = 12/224 (5%)
 Frame = +2

Query: 165 DAEILRKAMKGFGTDEQAIVDVVSNRSNDQRQQIKAAFKTMYGKDLIKDLKSELSGNMEE 224
           DA+ + KA+KG GTDE+A+++++  R+N Q   +K A+KTMY KD+  D++ + SG  + 
Sbjct: 134 DAKQINKAVKGLGTDERALIEIICTRTNAQLTAMKEAYKTMYQKDVETDIEGDTSGPFKR 313

Query: 225 LILALFMPS-----------TYYDAWSLRKAMQGA-GTQERVLIEILCTRTNQEIRDIVR 272
           L++     +              DA +L +A +   GT E     ++ +R+  ++R   +
Sbjct: 314 LLIGCLQANRPEGQEFDRNKAKQDAQALLEAGEKKWGTDESRFNVVIVSRSFPQLRATFQ 493

Query: 273 CYQLEFGRDLEKDIRSDTSGHFERLLVSMCQGNRDERQSVNHQMAQEDAQRLYQAGEGRL 332
            Y     +D+E  I S+ SG  +  ++++ +        V    A   A  L++A +G L
Sbjct: 494 EYAKLANKDIEDSISSEMSGDXKNGMLTVVR--------VIRSKATHFATELHRAMKG-L 646

Query: 333 GTDESCFNMILATRSFPQLKATMEAYSRMANRDLLSSVSREFSG 376
           GTD+     ++A+R    +    E + R   + L S +  + SG
Sbjct: 647 GTDDDTLVRVVASRCEVDMVQIKEEFQRNFKQTLYSFIVDDTSG 778

 Score = 35.8 bits (81), Expect = 0.036,   Method: Compositional matrix adjust.
 Identities = 20/62 (32%), Positives = 33/62 (53%)
 Frame = +2

Query: 169 LRKAMKGFGTDEQAIVDVVSNRSNDQRQQIKAAFKTMYGKDLIKDLKSELSGNMEELILA 228
           L +AMKG GTD+  +V VV++R      QIK  F+  + + L   +  + SG+   ++  
Sbjct: 623 LHRAMKGLGTDDDTLVRVVASRCEVDMVQIKEEFQRNFKQTLYSFIVDDTSGDYRLMLCN 802

Query: 229 LF 230
           L 
Sbjct: 803 LI 808
>36934
          Length = 667

 Score =  161 bits (408), Expect = 4e-40,   Method: Compositional matrix adjust.
 Identities = 88/204 (43%), Positives = 125/204 (61%), Gaps = 1/204 (0%)
 Frame = +3

Query: 162 AMRDAEILRKAMKGFG-TDEQAIVDVVSNRSNDQRQQIKAAFKTMYGKDLIKDLKSELSG 220
           A  DAE L KAM G G T E  +++++  RSN QRQ +K  +K MY +DL + L+SEL+G
Sbjct: 18  AAEDAERLHKAMSGMGVTHEDTVLEIIIKRSNSQRQTLKKKYKEMYKRDLAEHLQSELTG 197

Query: 221 NMEELILALFMPSTYYDAWSLRKAMQGAGTQERVLIEILCTRTNQEIRDIVRCYQLEFGR 280
           + EELIL L MP   YDA+ L KA+ G GT E VLI ILCT   +E+  +   Y+  +G 
Sbjct: 198 DFEELILGLLMPPVEYDAFCLNKAVDGLGTNEDVLIGILCTANPKELSSVKEVYKKTYGE 377

Query: 281 DLEKDIRSDTSGHFERLLVSMCQGNRDERQSVNHQMAQEDAQRLYQAGEGRLGTDESCFN 340
           DL+  I+ DTSG FE LL+++ +G RD+ +SVN + A++DAQ+L    + + G     F 
Sbjct: 378 DLDSAIKGDTSGGFEDLLLALSRGERDQSKSVNEKEAKQDAQKLCPDKK*KTGHG**NFQ 557

Query: 341 MILATRSFPQLKATMEAYSRMANR 364
            I    +  Q+KAT   Y ++  R
Sbjct: 558 YIDDKENKQQMKATFVEYEKLRVR 629

 Score = 68.9 bits (167), Expect = 4e-12,   Method: Compositional matrix adjust.
 Identities = 45/144 (31%), Positives = 73/144 (50%)
 Frame = +3

Query: 317 AQEDAQRLYQAGEGRLGTDESCFNMILATRSFPQLKATMEAYSRMANRDLLSSVSREFSG 376
           A EDA+RL++A  G   T E     I+  RS  Q +   + Y  M  RDL   +  E +G
Sbjct: 18  AAEDAERLHKAMSGMGVTHEDTVLEIIIKRSNSQRQTLKKKYKEMYKRDLAEHLQSELTG 197

Query: 377 YVESGLKTILQCALNRPAFFAERLYYSMKGAGTDDSTLVRIVVTRSEIDLVQIKQMFTQM 436
             E  +  +L   +   AF    L  ++ G GT++  L+ I+ T +  +L  +K+++ + 
Sbjct: 198 DFEELILGLLMPPVEYDAFC---LNKAVDGLGTNEDVLIGILCTANPKELSSVKEVYKKT 368

Query: 437 YQKTLSTMIASDTSGDYRKLLLAI 460
           Y + L + I  DTSG +  LLLA+
Sbjct: 369 YGEDLDSAIKGDTSGGFEDLLLAL 440

 Score = 47.0 bits (110), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 22/71 (30%), Positives = 45/71 (63%), Gaps = 1/71 (1%)
 Frame = +3

Query: 392 RPAFFAERLYYSMKGAG-TDDSTLVRIVVTRSEIDLVQIKQMFTQMYQKTLSTMIASDTS 450
           + A  AERL+ +M G G T + T++ I++ RS      +K+ + +MY++ L+  + S+ +
Sbjct: 15  KAAEDAERLHKAMSGMGVTHEDTVLEIIIKRSNSQRQTLKKKYKEMYKRDLAEHLQSELT 194

Query: 451 GDYRKLLLAIV 461
           GD+ +L+L ++
Sbjct: 195 GDFEELILGLL 227
>06659
          Length = 776

 Score =  159 bits (401), Expect = 3e-39,   Method: Compositional matrix adjust.
 Identities = 94/224 (41%), Positives = 139/224 (62%), Gaps = 3/224 (1%)
 Frame = -3

Query: 241 LRKAMQGAGTQERVLIEILCTRTNQEIRDIVRCYQLEFGRDLEKDIRSDTSGHFERLLVS 300
           L  A+ GAGT E+ LI+I+CTR N E+++I   Y+ EF  +LE+D+++DT G+F RL++S
Sbjct: 774 LHDAISGAGTDEKCLIDIMCTRDNDEMKEIKEKYKEEFESELEEDLQADTGGYFRRLMIS 595

Query: 301 MCQGNRD--ERQSVNHQMAQEDAQRLYQAGEGRLGTDESCFNMILATRSFPQLKATMEAY 358
           +C G RD       N   A EDAQ+  +AGE   GT+E+  N IL   S  QL  T+E Y
Sbjct: 594 LCVGGRDYDNWWXANEDKAVEDAQKFLEAGENAWGTEEADMNAILCRTSPAQLCKTIEKY 415

Query: 359 SRMA-NRDLLSSVSREFSGYVESGLKTILQCALNRPAFFAERLYYSMKGAGTDDSTLVRI 417
             +   + +  S+  E S  +  G   I++ A + P +FA RL     G GT D+ L+RI
Sbjct: 414 EELTEGKTMEESIRSECSDDLXDGYLAIVESARSMPRYFARRLNDCFSGLGTSDNDLIRI 235

Query: 418 VVTRSEIDLVQIKQMFTQMYQKTLSTMIASDTSGDYRKLLLAIV 461
           +V+RSE+DL  IKQ + +MY+K L+  + S+  GDY++LLLAI+
Sbjct: 234 IVSRSEVDLEAIKQAYEEMYEKPLTEAVESECGGDYKRLLLAIL 103

 Score = 65.5 bits (158), Expect = 5e-11,   Method: Compositional matrix adjust.
 Identities = 68/240 (28%), Positives = 115/240 (47%), Gaps = 15/240 (6%)
 Frame = -3

Query: 169 LRKAMKGFGTDEQAIVDVVSNRSNDQRQQIKAAFKTMYGKDLIKDLKSELSGNMEELILA 228
           L  A+ G GTDE+ ++D++  R ND+ ++IK  +K  +  +L +DL+++  G    L+++
Sbjct: 774 LHDAISGAGTDEKCLIDIMCTRDNDEMKEIKEKYKEEFESELEEDLQADTGGYFRRLMIS 595

Query: 229 LFMPSTYYDAW---SLRKAMQGA-----------GTQERVLIEILC-TRTNQEIRDIVRC 273
           L +    YD W   +  KA++ A           GT+E  +  ILC T   Q  + I + 
Sbjct: 594 LCVGGRDYDNWWXANEDKAVEDAQKFLEAGENAWGTEEADMNAILCRTSPAQLCKTIEKY 415

Query: 274 YQLEFGRDLEKDIRSDTSGHFERLLVSMCQGNRDERQSVNHQMAQEDAQRLYQAGEGRLG 333
            +L  G+ +E+ IRS+ S       +++ +  R         M +  A+RL     G LG
Sbjct: 414 EELTEGKTMEESIRSECSDDLXDGYLAIVESAR--------SMPRYFARRLNDCFSG-LG 262

Query: 334 TDESCFNMILATRSFPQLKATMEAYSRMANRDLLSSVSREFSGYVESGLKTILQCALNRP 393
           T ++    I+ +RS   L+A  +AY  M  + L  +V  E  G      K +L   LN P
Sbjct: 261 TSDNDLIRIIVSRSEVDLEAIKQAYEEMYEKPLTEAVESECGG----DYKRLLLAILNPP 94
>22178
          Length = 655

 Score =  101 bits (251), Expect(2) = 1e-30,   Method: Compositional matrix adjust.
 Identities = 48/79 (60%), Positives = 62/79 (78%)
 Frame = +1

Query: 385 ILQCALNRPAFFAERLYYSMKGAGTDDSTLVRIVVTRSEIDLVQIKQMFTQMYQKTLSTM 444
           I++ A N PA+FAERLY SMKGAGT+D  L+R +V+RSE DL  IKQ F +MY KTL++ 
Sbjct: 226 IVRVARNTPAYFAERLYKSMKGAGTNDKALIRAIVSRSENDLGFIKQEFQRMYGKTLASY 405

Query: 445 IASDTSGDYRKLLLAIVGQ 463
           I  DTSGDY+K+LLA+ G+
Sbjct: 406 IKGDTSGDYKKILLALCGE 462

 Score = 50.1 bits (118), Expect(2) = 1e-30,   Method: Compositional matrix adjust.
 Identities = 21/51 (41%), Positives = 35/51 (68%)
 Frame = +2

Query: 332 LGTDESCFNMILATRSFPQLKATMEAYSRMANRDLLSSVSREFSGYVESGL 382
           +GTDE  FN IL  R++ QL+AT +AY +++ +D+  ++  E SG +E+G 
Sbjct: 65  VGTDEETFNRILCLRNYGQLRATFDAYRQISGKDIEDAIKSEMSGNLEAGF 217

 Score = 51.2 bits (121), Expect = 8e-07,   Method: Compositional matrix adjust.
 Identities = 26/64 (40%), Positives = 43/64 (67%)
 Frame = +1

Query: 166 AEILRKAMKGFGTDEQAIVDVVSNRSNDQRQQIKAAFKTMYGKDLIKDLKSELSGNMEEL 225
           AE L K+MKG GT+++A++  + +RS +    IK  F+ MYGK L   +K + SG+ +++
Sbjct: 262 AERLYKSMKGAGTNDKALIRAIVSRSENDLGFIKQEFQRMYGKTLASYIKGDTSGDYKKI 441

Query: 226 ILAL 229
           +LAL
Sbjct: 442 LLAL 453

 Score = 35.4 bits (80), Expect = 0.054,   Method: Compositional matrix adjust.
 Identities = 19/56 (33%), Positives = 31/56 (55%)
 Frame = +2

Query: 177 GTDEQAIVDVVSNRSNDQRQQIKAAFKTMYGKDLIKDLKSELSGNMEELILALFMP 232
           GTDE+    ++  R+  Q +    A++ + GKD+   +KSE+SGN+E      F P
Sbjct: 68  GTDEETFNRILCLRNYGQLRATFDAYRQISGKDIEDAIKSEMSGNLE---AGFFWP 226

 Score = 34.3 bits (77), Expect = 0.12,   Method: Compositional matrix adjust.
 Identities = 17/50 (34%), Positives = 26/50 (52%)
 Frame = +2

Query: 246 QGAGTQERVLIEILCTRTNQEIRDIVRCYQLEFGRDLEKDIRSDTSGHFE 295
           +  GT E     ILC R   ++R     Y+   G+D+E  I+S+ SG+ E
Sbjct: 59  ESVGTDEETFNRILCLRNYGQLRATFDAYRQISGKDIEDAIKSEMSGNLE 208
>17882
          Length = 489

 Score = 76.3 bits (186), Expect(2) = 1e-23,   Method: Compositional matrix adjust.
 Identities = 35/56 (62%), Positives = 47/56 (83%)
 Frame = -1

Query: 408 GTDDSTLVRIVVTRSEIDLVQIKQMFTQMYQKTLSTMIASDTSGDYRKLLLAIVGQ 463
           GT+DS L+RI+V+RSEIDL  IK ++   Y+KTL + +ASDTSGDY++LLLAIVG+
Sbjct: 351 GTNDSRLIRIIVSRSEIDLQDIKDVYLSKYKKTLESAVASDTSGDYKRLLLAIVGR 184

 Score = 52.0 bits (123), Expect(2) = 1e-23,   Method: Compositional matrix adjust.
 Identities = 22/44 (50%), Positives = 33/44 (75%)
 Frame = -2

Query: 362 ANRDLLSSVSREFSGYVESGLKTILQCALNRPAFFAERLYYSMK 405
           A +DLLSS+S E SG  E+GL+ I++C  NRP +FA++L+  +K
Sbjct: 488 AGKDLLSSISSEMSGDFETGLRAIVRCMKNRPEYFADKLHDCIK 357

 Score = 42.0 bits (97), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 20/57 (35%), Positives = 36/57 (63%)
 Frame = -1

Query: 246 QGAGTQERVLIEILCTRTNQEIRDIVRCYQLEFGRDLEKDIRSDTSGHFERLLVSMC 302
           Q  GT +  LI I+ +R+  +++DI   Y  ++ + LE  + SDTSG ++RLL+++ 
Sbjct: 360 QVLGTNDSRLIRIIVSRSEIDLQDIKDVYLSKYKKTLESAVASDTSGDYKRLLLAIV 190
>12136
          Length = 445

 Score = 90.9 bits (224), Expect = 9e-19,   Method: Compositional matrix adjust.
 Identities = 48/106 (45%), Positives = 69/106 (65%), Gaps = 7/106 (6%)
 Frame = +3

Query: 210 LIKDLKSELSGNMEELILALFMPSTYYDAWSLRKAMQGAGTQERVLIEILCTRTNQEIRD 269
           LI+++K ELSG+ +EL++ALF+    YDAW +++A+ G GT E  L+EIL TRTN +I++
Sbjct: 3   LIEEIKGELSGDYKELVMALFVAPAEYDAWCIKEAIYGPGTDEMALMEILMTRTNAQIKE 182

Query: 270 IVRCY-----QLEFGR--DLEKDIRSDTSGHFERLLVSMCQGNRDE 308
           +   Y         GR   +E+DI  D SG F+RLL+S  QG R E
Sbjct: 183 LRSIYPSVLNDHYHGRTPKIEQDIEDDCSGDFKRLLISASQGGRFE 320
>13827
          Length = 483

 Score = 72.4 bits (176), Expect(2) = 4e-15,   Method: Compositional matrix adjust.
 Identities = 32/58 (55%), Positives = 42/58 (72%)
 Frame = -1

Query: 405 KGAGTDDSTLVRIVVTRSEIDLVQIKQMFTQMYQKTLSTMIASDTSGDYRKLLLAIVG 462
           +G GTDD TL+R+VVTR E+D+ QIKQ F   Y + L   +  D SGDYR+L+LA+VG
Sbjct: 444 RGMGTDDRTLIRVVVTRCEVDMKQIKQEFQNRYGQALEAFVRDDISGDYRRLMLALVG 271

 Score = 26.6 bits (57), Expect(2) = 4e-15,   Method: Compositional matrix adjust.
 Identities = 10/15 (66%), Positives = 13/15 (86%)
 Frame = -3

Query: 394 AFFAERLYYSMKGAG 408
            +FA+RLY+SMKG G
Sbjct: 478 GYFADRLYHSMKGDG 434

 Score = 41.2 bits (95), Expect = 8e-04,   Method: Compositional matrix adjust.
 Identities = 23/70 (32%), Positives = 38/70 (54%), Gaps = 2/70 (2%)
 Frame = -1

Query: 174 KGFGTDEQAIVDVVSNRSNDQRQQIKAAFKTMYGKDLIKDLKSELSGNMEELILALF--M 231
           +G GTD++ ++ VV  R     +QIK  F+  YG+ L   ++ ++SG+   L+LAL   +
Sbjct: 444 RGMGTDDRTLIRVVVTRCEVDMKQIKQEFQNRYGQALEAFVRDDISGDYRRLMLALVGGI 265

Query: 232 PSTYYDAWSL 241
           P      W L
Sbjct: 264 P*ARQ*IWPL 235
>29756
          Length = 496

 Score = 64.3 bits (155), Expect = 9e-11,   Method: Compositional matrix adjust.
 Identities = 34/88 (38%), Positives = 51/88 (57%), Gaps = 1/88 (1%)
 Frame = +3

Query: 143 PASMTQGTQGTILPASNFDAMRDAEILRKAMKGFGTDEQAIVDVVSNRSNDQRQQIKAAF 202
           P     G +    P   F+A  D + LRKAMKGFGTDE+AI+D++  R++DQRQ +K  +
Sbjct: 213 PHHTKSGRKER*KPYPRFNAEEDVQKLRKAMKGFGTDEKAIIDILGYRTSDQRQNLKLMY 392

Query: 203 KTMYGKDLIKDL-KSELSGNMEELILAL 229
           K ++ K       +   +G  E+ +LAL
Sbjct: 393 KNLFWKRFGAGF*RVN*AGAFEDAMLAL 476

 Score = 28.5 bits (62), Expect = 5.9,   Method: Compositional matrix adjust.
 Identities = 16/51 (31%), Positives = 27/51 (52%), Gaps = 4/51 (7%)
 Frame = +3

Query: 393 PAFFAE----RLYYSMKGAGTDDSTLVRIVVTRSEIDLVQIKQMFTQMYQK 439
           P F AE    +L  +MKG GTD+  ++ I+  R+      +K M+  ++ K
Sbjct: 258 PRFNAEEDVQKLRKAMKGFGTDEKAIIDILGYRTSDQRQNLKLMYKNLFWK 410
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|12746442|ref|NP_075547.1| eukaryotic elongation
factor, selenocysteine-tRNA-specific [Mus musculus]
         (583 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

31464                                                                 233   8e-71
15991                                                                  68   1e-11
00709                                                                  49   5e-06
22349                                                                  44   2e-04
04497                                                                  39   0.008
15617                                                                  29   6.1  
14064                                                                  28   7.8  
00725                                                                  28   9.3  
>31464
          Length = 946

 Score =  233 bits (593), Expect(2) = 8e-71,   Method: Compositional matrix adjust.
 Identities = 118/214 (55%), Positives = 149/214 (69%)
 Frame = +1

Query: 118 VIGQIACQKLVVVLNKIDLLAEGKRQAAIDKMTKKMQKTLENTKFRGAPIIPVXXXXXXX 177
           VIGQI CQ +VVVLNK DL+     +    +   +  KTLE+T+F+  PI+ V       
Sbjct: 10  VIGQITCQSMVVVLNKTDLIHRTSDRPPSKR*RSECGKTLEDTQFKDCPIVAVAAKPGGP 189

Query: 178 XXXXXXXXXXISELIELLKSQISIPTRDPSGPFLMSVDHCFSIKGQGTVMTGTILSGTIS 237
                     + +LI  L+ Q  +P R+P GPF+ SVDHCFS++ QGTV+TGT +SG+++
Sbjct: 190 EAGDIAADG-MGDLIGELQKQTYMPRRNPDGPFIFSVDHCFSLRXQGTVLTGTAISGSVA 366

Query: 238 LGDSVEIPALKVVKKVKSMQMFHTPVTSAMQGDRLGICVTQFDPKLLERGLVCAPESLHT 297
           + D+VEIPA+KV KKVKSMQMF  PV   +QGDR GICVTQFDPKLLERGLVC P +L T
Sbjct: 367 VNDTVEIPAMKVQKKVKSMQMFRNPVDRLVQGDRAGICVTQFDPKLLERGLVCHPGALFT 546

Query: 298 VHAALISVEKIPYFRGPLQTKAKFHITVGHETVM 331
           VHA + SV KI YF+G + TKAKFHITVGHET+M
Sbjct: 547 VHAFIASVHKIAYFKGTVSTKAKFHITVGHETIM 648

 Score = 53.5 bits (127), Expect(2) = 8e-71,   Method: Compositional matrix adjust.
 Identities = 28/71 (39%), Positives = 38/71 (53%), Gaps = 2/71 (2%)
 Frame = +2

Query: 353 FDLSREYLFQEQYLCKDSMPTATEGDDEADPKAGHAPGGH--CPRQQWALVEFEKPVTCP 410
            D S EY +QE+        +A   DD+ +  A     GH   P +Q+ L+E EKPVTC 
Sbjct: 743 LDFSAEYAYQEELFAD----SALSPDDKTNGAASSEESGHGTTPVKQYVLIELEKPVTCS 910

Query: 411 RLCLVIGSRLD 421
              L+IGS+LD
Sbjct: 911 NNALMIGSKLD 943
>15991
          Length = 1629

 Score = 68.2 bits (165), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 63/277 (22%), Positives = 106/277 (38%), Gaps = 21/277 (7%)
 Frame = -3

Query: 36   FDKQPQSRERGITLDLGFSCFVVPLPGAEPGSSDTLLQVTLVDCPGHASLIRTIIGGAQI 95
             DK    RERGIT+D+    F           +D    VT++D PGH   I+ +I G   
Sbjct: 1498 LDKLKAERERGITIDIALWKF----------ETDKYY-VTIIDAPGHRDFIKNMITGTSQ 1352

Query: 96   IDLMMLVIDVTKG-------MQTQSAE-CLVIGQIACQKLVVVLNKIDLLAEGKRQAAID 147
             D  +LV+   KG          Q+ E  L+   +  ++L+V +NK+D           +
Sbjct: 1351 ADCAVLVVAAGKGEFEAGISKDGQTREHALLAYTLGVKQLIVAVNKMDSTEPPYSMDRFE 1172

Query: 148  KMTKKMQKTLENTKFR-------------GAPIIPVXXXXXXXXXXXXXXXXXISELIEL 194
            ++ K++   ++   +              G  ++                     E ++ 
Sbjct: 1171 EIKKEVSTYIKKIGYNPNTVAFVPISGWVGDNMMEASTKIVHKWKIERKEGKAEGETLKE 992

Query: 195  LKSQISIPTRDPSGPFLMSVDHCFSIKGQGTVMTGTILSGTISLGDSVEIPALKVVKKVK 254
                I  PTR       + +   + I G GTV  G + +G +  G  V      +  +VK
Sbjct: 991  ALDAILPPTRPTDKALRLPLQDVYKIGGIGTVPVGRVETGILKPGTVVTFAPGGLTTEVK 812

Query: 255  SMQMFHTPVTSAMQGDRLGICVTQFDPKLLERGLVCA 291
            S++M H  +  A+ GD +G  V     K + RG V  
Sbjct: 811  SVEMHHEQLQEALPGDNVGFNVKNVSVKDIRRGNVAG 701
>00709
          Length = 1076

 Score = 49.3 bits (116), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 33/146 (22%), Positives = 65/146 (44%), Gaps = 11/146 (7%)
 Frame = -2

Query: 36  FDKQPQSRERGITLDLGFSCFVVPLPGAEPGSSDTLLQVTLVDCPGHASLIRTIIGGAQI 95
            DK    RERGIT+D+    F             T   VT++D PGH   I+ +I G   
Sbjct: 730 LDKLKAERERGITIDIALWKF-----------ETTKYYVTIIDAPGHRDFIKNMITGTSQ 584

Query: 96  IDLMMLVI---------DVTKGMQTQSAECLVIGQIACQKLVVVLNKIDLLAEGKRQAAI 146
            D  +L++          ++K  QT+    L+   +  ++L++ +NK+D  +    +   
Sbjct: 583 ADCAVLIVASGTGEFEAGISKEGQTRE-HALLAYTLGVKQLIIGVNKMDSTSPAYSETRF 407

Query: 147 DKMTKKMQKTLENTKF--RGAPIIPV 170
           +++ K++   ++   F  +    +P+
Sbjct: 406 NEIQKEVSGYIKKIGFNPKAVAFVPI 329
>22349
          Length = 662

 Score = 43.5 bits (101), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 31/110 (28%), Positives = 49/110 (44%), Gaps = 10/110 (9%)
 Frame = -2

Query: 36  FDKQPQSRERGITLDLGFSCFVVPLPGAEPGSSDTLLQVTLVDCPGHASLIRTIIGGAQI 95
            D   + RE+G T+++G + F   L              T++D PGH S +  +I GA  
Sbjct: 334 LDTNNEEREKGKTVEVGRAFFETELK-----------HFTVLDAPGHKSFVPNMICGASQ 188

Query: 96  IDLMMLVIDVTKG----------MQTQSAECLVIGQIACQKLVVVLNKID 135
            DL +LVI   +G           +  S  C    Q   + L+V++NK+D
Sbjct: 187 ADLAILVISARRGEF*DWFLSEEARHVSMPCW*RRQ-GVRHLIVLINKMD 41
>04497
          Length = 1188

 Score = 38.5 bits (88), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 47/184 (25%), Positives = 77/184 (41%), Gaps = 15/184 (8%)
 Frame = -2

Query: 74  VTLVDCPGHASLIRTIIGG--AQIIDLMMLVIDVTKGMQTQSAECLVIGQIACQKLVVVL 131
           +T +D  GH   ++T + G      D  ML+I    G+   + E L +       + VV+
Sbjct: 986 ITFIDLAGHERYLKTTVFGMTGHAPDFAMLMIGANAGVIGMTKEHLGLALALNVPVFVVV 807

Query: 132 NKIDLLAEGKRQAAIDKMTKKMQKTLENTKFRGAPII---------PVXXXXXXXXXXXX 182
            K+D+      Q  +  +T+     L++   R  P+I                       
Sbjct: 806 TKVDMCPPNVLQETLKLLTR----ILKSPGCRKIPVIVQNKDDVICSATNFTSERMCPVF 639

Query: 183 XXXXXISELIELLKSQISI-PTR---DPSGPFLMSVDHCFSIKGQGTVMTGTILSGTISL 238
                  E +ELLK  +++  TR   D S P    +D  FS+ G GTV++GT+L G I L
Sbjct: 638 QVSNVTGENLELLKMFLNLLSTRVKCDLSKPPEFQIDDTFSVPGVGTVVSGTLLQGYIKL 459

Query: 239 GDSV 242
            D++
Sbjct: 458 NDTL 447
>15617
          Length = 595

 Score = 28.9 bits (63), Expect = 6.1,   Method: Compositional matrix adjust.
 Identities = 11/44 (25%), Positives = 21/44 (47%)
 Frame = -3

Query: 74  VTLVDCPGHASLIRTIIGGAQIIDLMMLVIDVTKGMQTQSAECL 117
           + L+D PGH      +    ++ D  ++V+D   G+  Q+   L
Sbjct: 185 INLIDSPGHVDFSSEVTAALRVTDGALVVVDCVSGVCVQTETVL 54
>14064
          Length = 1723

 Score = 28.5 bits (62), Expect = 7.8,   Method: Compositional matrix adjust.
 Identities = 16/44 (36%), Positives = 22/44 (50%), Gaps = 2/44 (4%)
 Frame = +2

Query: 74  VTLVDCPGHASLIRTIIGG--AQIIDLMMLVIDVTKGMQTQSAE 115
           +TL+D  GH   +RT I G      D  MLV+  T G+   + E
Sbjct: 140 ITLIDLAGHHRYLRTTIVGLTGNCPDFAMLVVSATSGIVGMTKE 271
>00725
          Length = 1555

 Score = 28.1 bits (61), Expect = 9.3,   Method: Compositional matrix adjust.
 Identities = 14/51 (27%), Positives = 28/51 (54%), Gaps = 1/51 (1%)
 Frame = +2

Query: 525 PESKKILTPTLKKRSRAGRGETTKPEEGTERPEPIQPV-TLNLSFKRYVFD 574
           P+  +++ PT+ +  +  R   T+P EG  + E + P+  L+    RY++D
Sbjct: 116 PDGWELIEPTIDELDQKMREAETEPHEGKRKVEAMWPIFRLHHQKSRYIYD 268
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|40018610|ref|NP_796188.2| U5 snRNP-specific protein,
200 kDa [Mus musculus]
         (2136 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

30067                                                                 265   1e-70
05560                                                                 221   2e-57
32034                                                                 207   5e-53
09566                                                                  78   7e-22
11624                                                                  40   0.014
14946                                                                  35   0.25 
>30067
          Length = 445

 Score =  265 bits (677), Expect = 1e-70,   Method: Compositional matrix adjust.
 Identities = 123/147 (83%), Positives = 138/147 (93%)
 Frame = -3

Query: 1058 KINVLLQAFISQLKLEGFALMADMVYVTQSAGRLMRAIFEIVLNRGWAQLTDKTLNLCKM 1117
            K+NVLLQA+ISQLKLEGFALM DMV++TQSAGRL+RA+FEIVL RGWAQL DK + LCKM
Sbjct: 443  KVNVLLQAYISQLKLEGFALMVDMVFITQSAGRLVRALFEIVLYRGWAQLADKAVALCKM 264

Query: 1118 IDKRMWQSMCPLRQFRKLPEEVVKKIEKKNFPFERLYDLNHNEIGELIRMPKMGKTIHKY 1177
            ++KRMWQSM PLRQFR++PEEVV+KIEKKNFPFERLYDLNH+EIGELIR PKMG TIHKY
Sbjct: 263  VNKRMWQSMSPLRQFRRIPEEVVRKIEKKNFPFERLYDLNHHEIGELIRTPKMGTTIHKY 84

Query: 1178 VHLFPKLELSVHLQPITRSTLKVELTI 1204
            VH FPKLELSV++QPITRSTLKVELTI
Sbjct: 83   VHQFPKLELSVNVQPITRSTLKVELTI 3

 Score = 57.8 bits (138), Expect = 5e-08,   Method: Compositional matrix adjust.
 Identities = 40/137 (29%), Positives = 68/137 (49%), Gaps = 3/137 (2%)
 Frame = -3

Query: 1890 KTNLLLQAHLSRMQLSA-ELQSDTEEILSKAIRLIQACVDVLSSNGWLSPALAAMELAQM 1948
            K N+LLQA++S+++L    L  D   I   A RL++A  +++   GW   A  A+ L +M
Sbjct: 443  KVNVLLQAYISQLKLEGFALMVDMVFITQSAGRLVRALFEIVLYRGWAQLADKAVALCKM 264

Query: 1949 VTQAMWSKDSYLKQLPHFTSEHIKRCTDKG--VESVFDIMEMEDEERNALLQLTDSQIAD 2006
            V + MW   S L+Q      E +++   K    E ++D+   E  E    L  T      
Sbjct: 263  VNKRMWQSMSPLRQFRRIPEEVVRKIEKKNFPFERLYDLNHHEIGE----LIRTPKMGTT 96

Query: 2007 VARFCNRYPNIELSYEV 2023
            + ++ +++P +ELS  V
Sbjct: 95   IHKYVHQFPKLELSVNV 45
>05560
          Length = 561

 Score =  221 bits (564), Expect = 2e-57,   Method: Compositional matrix adjust.
 Identities = 109/148 (73%), Positives = 121/148 (81%)
 Frame = +2

Query: 1   MADVTARSLQYEYKANSNLVLQADRSLIDRTRRDEPTGEVLSLVGKLEGTRMGDKAQRTK 60
           MAD TARSLQYEYKANSNLVL  DRSLIDR  RDE TGEV++LVGKL GTRMGDK+Q+TK
Sbjct: 116 MADHTARSLQYEYKANSNLVLSVDRSLIDRRARDEATGEVMTLVGKLTGTRMGDKSQKTK 295

Query: 61  PQMQXXXXXXXXXXXXXXHDMNKMKGYTLLSEGIDEMVGIIYKPKTKETRETYEVLLSFI 120
           P +               HDM KMKG TLL+ GIDEMVGI+Y+PKT ETR+TYEVLLSFI
Sbjct: 296 PPLMEERKNKRRKRDEAQHDMVKMKGTTLLTGGIDEMVGIMYRPKTVETRQTYEVLLSFI 475

Query: 121 QAALGDQPRDILCGAADEVLAVLKNEKL 148
           QAALGDQPRDILCGAADEVLAVLKN+++
Sbjct: 476 QAALGDQPRDILCGAADEVLAVLKNDRM 559
>32034
          Length = 386

 Score =  207 bits (526), Expect = 5e-53,   Method: Compositional matrix adjust.
 Identities = 91/124 (73%), Positives = 110/124 (88%)
 Frame = +2

Query: 454 PFGSEEQLLPVEKLPKYAQAGFEGFKTLNRIQSKLYRAALETDENLLLCAPTGAGKTNVA 513
           PF  +E L+P+++LPKYAQ  F+ FK+LNRIQS+L++AA+ETD+NLLLCAPTGAGKTNVA
Sbjct: 14  PFDDDESLVPIDRLPKYAQPAFDSFKSLNRIQSRLFKAAMETDQNLLLCAPTGAGKTNVA 193

Query: 514 LMCMLREIGKHINMDGTINVDDFKIIYIAPMRSLVQEMVGSFGKRLATYGITVAELTGDH 573
           L+C+L EIGKH+N DGTIN DDFKIIY+APMRSLVQEMVG+F  RL +YGI VAELTGDH
Sbjct: 194 LLCILHEIGKHVNADGTINTDDFKIIYVAPMRSLVQEMVGNFSLRLQSYGIKVAELTGDH 373

Query: 574 QLCK 577
           QL +
Sbjct: 374 QLTR 385

 Score = 49.7 bits (117), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 30/98 (30%), Positives = 52/98 (53%), Gaps = 9/98 (9%)
 Frame = +2

Query: 1323 DKFPFFNPIQTQVFNTVYNSDDNVFVGAPTGSGKTICAEFAILRMLLQ--NSEG------ 1374
            D F   N IQ+++F     +D N+ + APTG+GKT  A   IL  + +  N++G      
Sbjct: 80   DSFKSLNRIQSRLFKAAMETDQNLLLCAPTGAGKTNVALLCILHEIGKHVNADGTINTDD 259

Query: 1375 -RCVYITPMEALAEQVYMDWYEKFQDRLNKKVVLLTGE 1411
             + +Y+ PM +L +++  ++  + Q     KV  LTG+
Sbjct: 260  FKIIYVAPMRSLVQEMVGNFSLRLQS-YGIKVAELTGD 370
>09566
          Length = 391

 Score = 77.8 bits (190), Expect(2) = 7e-22,   Method: Composition-based stats.
 Identities = 39/44 (88%), Positives = 41/44 (93%), Gaps = 1/44 (2%)
 Frame = +1

Query: 102 YKP-KTKETRETYEVLLSFIQAALGDQPRDILCGAADEVLAVLK 144
           Y P KT ETR+TYEVLLSFIQAALGDQPRDILCGAADEVLAVL+
Sbjct: 250 YVPTKTVETRQTYEVLLSFIQAALGDQPRDILCGAADEVLAVLR 381

 Score = 47.0 bits (110), Expect(2) = 7e-22,   Method: Composition-based stats.
 Identities = 20/27 (74%), Positives = 24/27 (88%)
 Frame = +2

Query: 79  HDMNKMKGYTLLSEGIDEMVGIIYKPK 105
           HDM KMKG TLL+ GIDEMVGI+Y+P+
Sbjct: 185 HDMVKMKGTTLLTGGIDEMVGIMYRPR 265

 Score = 31.2 bits (69), Expect = 4.3,   Method: Compositional matrix adjust.
 Identities = 14/17 (82%), Positives = 15/17 (88%)
 Frame = +1

Query: 1   MADVTARSLQYEYKANS 17
           MAD TARSLQYEYKA +
Sbjct: 115 MADHTARSLQYEYKATA 165
>11624
          Length = 2257

 Score = 39.7 bits (91), Expect = 0.014,   Method: Compositional matrix adjust.
 Identities = 21/48 (43%), Positives = 28/48 (58%), Gaps = 2/48 (4%)
 Frame = -3

Query: 1345 NVFVGAPTGSGKTICAEFAILRMLLQN--SEGRCVYITPMEALAEQVY 1390
            ++ V APTGSGKT+     I++ L Q      R V + P+  LAEQVY
Sbjct: 1811 DICVSAPTGSGKTLAYTLPIIQCLKQRMVPHVRAVIVLPVRDLAEQVY 1668
>14946
          Length = 1599

 Score = 35.4 bits (80), Expect = 0.25,   Method: Composition-based stats.
 Identities = 28/81 (34%), Positives = 36/81 (44%), Gaps = 11/81 (13%)
 Frame = -3

Query: 932  SPTLY--GISHDDLKGDPLLDQRRLDLVHTAALMLDKNNLVKYDKKTGNFQVTELGRIAS 989
            +PT+Y  G+S D + GDP L    LD   TA      NNLV Y    GN +  E  ++ S
Sbjct: 1582 NPTIYSVGVSEDRVVGDPFLQVTALDADFTAP-----NNLVTY-TLAGNSKALEYFQVGS 1421

Query: 990  H---------YYITNDTVQTY 1001
                       Y+  D  QTY
Sbjct: 1420 SSGQLSVLQPLYLDQDRTQTY 1358
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|149233605|ref|XP_980514.2| PREDICTED:
ADP-ribosylation factor guanine nucleotide-exchange factor 1(brefeldin
A-inhibited) [Mus musculus]
         (1846 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

25800                                                                 264   2e-70
11688                                                                 247   3e-65
30249                                                                  76   1e-13
20966                                                                  42   0.002
13952                                                                  39   0.028
17762                                                                  35   0.28 
>25800
          Length = 431

 Score =  264 bits (675), Expect = 2e-70,   Method: Compositional matrix adjust.
 Identities = 123/140 (87%), Positives = 130/140 (92%)
 Frame = +2

Query: 1190 DHFNKVGCNPNEDVAIFAVDSLRQLSMKFLEKGELANFRFQKDFLRPFEHIMKRNRSPTI 1249
            DHFNKVGC+P EDVA FAVDSLRQLSMKF+EKGE ANFRFQKDFLRPFEHIMKRNRSPTI
Sbjct: 2    DHFNKVGCSPMEDVAFFAVDSLRQLSMKFIEKGEFANFRFQKDFLRPFEHIMKRNRSPTI 181

Query: 1250 RDMVVRCIAQMVNSQAANIRSGWKNIFSVFHLAASDQDESIVELAFQTTGHIVTLVFEKH 1309
            RDMVVRC+AQMVNSQAA+I+SGWKNIFSVFHLAASD DE IVELAFQTTG I+  VFEKH
Sbjct: 182  RDMVVRCVAQMVNSQAASIKSGWKNIFSVFHLAASDHDEGIVELAFQTTGKIILSVFEKH 361

Query: 1310 FPATIDSFQDAVKCLSEFAC 1329
            F + IDSFQDAVKCLSEFAC
Sbjct: 362  FASIIDSFQDAVKCLSEFAC 421
>11688
          Length = 590

 Score =  247 bits (631), Expect = 3e-65,   Method: Compositional matrix adjust.
 Identities = 119/184 (64%), Positives = 143/184 (77%), Gaps = 5/184 (2%)
 Frame = +1

Query: 1607 EQKLFAALLIKCVVQLELIQTIDNIVFFPATSKKEDAENLAAAQRDAVDFDVR-----VD 1661
            +Q+LF  LLI+CVVQLELIQTIDNIVFFPATS+KEDAENLA AQ    +  +      + 
Sbjct: 37   DQQLFQGLLIRCVVQLELIQTIDNIVFFPATSRKEDAENLAVAQGSVDECQLHEPGHEIQ 216

Query: 1662 TQDQGMYRFLTSQQLFKLLDCLLESHRFAKAFNSNNEQRTALWKAGFKGKSKPNLLKQET 1721
             +DQGMY+FL+SQQL    DCLL+SHRFAK FNSN+EQR  LWKAGFKGK+KPNLLKQET
Sbjct: 217  HEDQGMYQFLSSQQLLMFTDCLLQSHRFAKQFNSNHEQRNVLWKAGFKGKAKPNLLKQET 396

Query: 1722 SSLACGLRILFRMYMDESRVSAWEEVQQRLLNVCREALSYFLTLTSESHREAWTNXXXXX 1781
             SLAC  RILFRMY DE+R  AW +V+++LL+VC EAL YFL+L S+SHREAW +     
Sbjct: 397  QSLACMFRILFRMYNDETRTDAWPQVEEKLLHVCSEALEYFLSLQSDSHREAWCSLLLLI 576

Query: 1782 XTKV 1785
             T++
Sbjct: 577  ITRM 588
>30249
          Length = 822

 Score = 75.9 bits (185), Expect = 1e-13,   Method: Compositional matrix adjust.
 Identities = 40/82 (48%), Positives = 55/82 (67%), Gaps = 3/82 (3%)
 Frame = -2

Query: 790 EAQKIDRLMEKFAARYLECNQGQTL-FASADTAYVLAYSIIMLTTDLHSPQVK--NKMTK 846
           EAQKI+RLME FA RY +CN  Q   F + DT ++LA++IIML TDLH+  VK   KM  
Sbjct: 821 EAQKIERLMEAFAERYCQCNPDQVKNFKTFDTVFLLAFAIIMLNTDLHNSSVKPERKMKL 642

Query: 847 EQYIKMNRGINDSKDLPEEYLS 868
           E +++  RGI+D +D+  +  S
Sbjct: 641 EDFVRNLRGIDDGEDVDGDLAS 576
>20966
          Length = 686

 Score = 42.0 bits (97), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 17/50 (34%), Positives = 32/50 (64%)
 Frame = -1

Query: 538 SFDHKWMVIQTLTRICADAQSVVDIYVNYDCDLNAANIFERLVNDLSKIA 587
           ++D + + ++++ ++      V ++Y+NYDCDL  +N+FE L   LSK A
Sbjct: 683 TYDQREIALESIVQLWRIPGLVTELYLNYDCDLYCSNLFEELTKLLSKNA 534

 Score = 41.6 bits (96), Expect = 0.003,   Method: Composition-based stats.
 Identities = 19/45 (42%), Positives = 29/45 (64%), Gaps = 2/45 (4%)
 Frame = -3

Query: 692 LKQQKEIIEQGIDLFNKKPKRGIQYLQEQGMLGT--TPEDIAQFL 734
           ++ ++    QG + FN+KP +GI +LQEQG+L T   P  +A FL
Sbjct: 156 VQTKERAYNQGTEYFNQKPAKGIAFLQEQGLLATPXDPGQVATFL 22
>13952
          Length = 577

 Score = 38.5 bits (88), Expect = 0.028,   Method: Compositional matrix adjust.
 Identities = 17/39 (43%), Positives = 26/39 (66%)
 Frame = -3

Query: 845 TKEQYIKMNRGINDSKDLPEEYLSAIYNEIAGKKISMKE 883
           T E++I+MNR IND   LPEE L+++Y+ I  +   + E
Sbjct: 575 TVERFIQMNRDINDGDSLPEELLTSLYDSIKKEPFKIPE 459
>17762
          Length = 1950

 Score = 35.0 bits (79), Expect = 0.28,   Method: Composition-based stats.
 Identities = 18/49 (36%), Positives = 24/49 (48%), Gaps = 5/49 (10%)
 Frame = -1

Query: 1142 RWLC----AVSMDELLSTTH-PRMFSLQKIVEISYYNMGRIRLQWSRIW 1185
            RW C         EL S  H PR         I+ YN+ R++L+WSR+W
Sbjct: 861  RWTC*EPAGEGRWELQSNQHRPRGLGKSVPTSINQYNLDRLKLKWSRVW 715
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|27753995|ref|NP_083296.2| ATP-binding cassette,
sub-family B (MDR/TAP), member 8 [Mus musculus]
         (717 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

05764                                                                 263   2e-70
01623                                                                 258   8e-69
02301                                                                 209   4e-54
22529                                                                 103   2e-22
01142                                                                 103   4e-22
15744                                                                  54   5e-16
30281                                                                  78   1e-14
32946                                                                  65   8e-11
19777                                                                  55   7e-08
12308                                                                  52   7e-07
22801                                                                  45   7e-05
03538                                                                  45   8e-05
19618                                                                  44   2e-04
27295                                                                  39   0.006
20290                                                                  39   0.007
18248                                                                  30   2.4  
38795                                                                  30   2.9  
>05764
          Length = 1395

 Score =  263 bits (672), Expect = 2e-70,   Method: Compositional matrix adjust.
 Identities = 141/322 (43%), Positives = 196/322 (60%), Gaps = 1/322 (0%)
 Frame = -2

Query: 374  GTLFIGGSLVAGQQLKGGDLMSFLVASQTVQRSMASLSVLFGQVVRGLSAGARVFEYMAL 433
            G    G  LV   ++   ++    +A     + +   S       +G  A A +F  M +
Sbjct: 1370 GCFRFGAYLVGRGEMNAEEVYRVFMAMTLAGQVVGQTSSFLPDYGKGRLAAAYIFRMMRI 1191

Query: 434  SPVIPLTGGYCIPNKDIRGSITFQNVTFSYPCRPGFNVLKDFTLKLPSGKIVALVGQSGG 493
             P I       I  KD +G+I  + V F YP RP   VLK  +L++ +G+  ALVG SG 
Sbjct: 1190 EPSIDNCSTTGI-RKDAKGNIKVEKVEFCYPTRPEIQVLKGISLEISAGQTAALVGISGC 1014

Query: 494  GKTTVASLLERFYDPEAGSVTLDGHDLRTLNPSWLRGQVIGFISQEPVLFATTIMENIRF 553
            GK+T+ SLL+R+YDP  G + +DG D+R  N + LR  ++  +SQEP+LF  +I +NI++
Sbjct: 1013 GKSTIISLLQRYYDPSKGRLLVDGTDVRDYNITALR-SLLSVVSQEPILFDCSIRDNIQY 837

Query: 554  G-KLDASDEEVYTAAREANAHEFISSFPDGYSTVVGERGTTLSGGQKQRLAIARALIKQP 612
            G + D    ++  A + AN HEFI+S P GY T VG +GT LSGGQKQR+AIARAL++ P
Sbjct: 836  GLESDVPMPDIIAACKTANIHEFIASLPQGYDTQVGGKGTQLSGGQKQRVAIARALVRNP 657

Query: 613  TVLILDEATSALDAESERVVQEALDRASAGRTVLVIAHRLSTVRAAHSIIVMANGQVCEA 672
             +L+LDEATSALD ESE++VQ ALD A  GRT +VIAHRLST++ A  I VM NGQ+ E 
Sbjct: 656  IILLLDEATSALDTESEKLVQAALDNAREGRTCIVIAHRLSTIQNADVIFVMENGQILEK 477

Query: 673  GTHEELLKKGGLYSELIRRQTL 694
            G H+ELL   G Y+  +  Q +
Sbjct: 476  GNHQELLALQGAYAGFVSNQKI 411
>01623
          Length = 1414

 Score =  258 bits (658), Expect = 8e-69,   Method: Compositional matrix adjust.
 Identities = 123/249 (49%), Positives = 182/249 (73%), Gaps = 4/249 (1%)
 Frame = +3

Query: 450 IRGSITFQNVTFSYPCRPGFNVLKDFTLKLPSGKIVALVGQSGGGKTTVASLLERFYDPE 509
           + G+I F+++ F+YP RP   + K F L+  +G++ A+VG SG GK+TV  LL R+YDP 
Sbjct: 15  LEGNIEFRDIHFAYPGRPDVAIFKGFNLQARAGQVTAVVGPSGSGKSTVCGLLLRYYDPN 194

Query: 510 AGSVTLDGHDLRTLNPSWLRGQVIGFISQEPVLFATTIMENIRFGKLD---ASDEEVYTA 566
           AG V LDG ++  L+P+WLR   IG +SQEP+LF+ ++ ENI +G ++    +  ++  A
Sbjct: 195 AGQVMLDGQNIAELDPTWLRSH-IGTVSQEPILFSCSVAENIAYGAVNPDAVTLGQIEDA 371

Query: 567 AREANAHEFISSFPDGYSTVVGERGTTLSGGQKQRLAIARALIKQPTVLILDEATSALDA 626
           AR+ANA  F+S+FP G  T+VGERG  LSGGQ+QR+AIARA++K P +L+LDEATSALDA
Sbjct: 372 ARKANAFNFVSTFPLGLDTMVGERGMMLSGGQRQRIAIARAILKNPEILLLDEATSALDA 551

Query: 627 ESERVVQEALDRASAGRTVLVIAHRLSTVRAAHSIIVMANGQVCEAGTHEELLK-KGGLY 685
           ESE +VQ+AL++   GRTV+ IAHRLST++ A+ I V+ +G V E G++++L+    G++
Sbjct: 552 ESEYLVQDALEKLMGGRTVITIAHRLSTIKTANQIAVLTDGVVAEMGSYQDLIAINDGIF 731

Query: 686 SELIRRQTL 694
            +L+ RQT+
Sbjct: 732 RKLVERQTI 758
>02301
          Length = 1098

 Score =  209 bits (531), Expect = 4e-54,   Method: Compositional matrix adjust.
 Identities = 112/240 (46%), Positives = 156/240 (65%)
 Frame = -2

Query: 464  PCRPGFNVLKDFTLKLPSGKIVALVGQSGGGKTTVASLLERFYDPEAGSVTLDGHDLRTL 523
            P RP    L  +   + +G++V L G   GGK+T  SLL+ FY P +G V LDG  +   
Sbjct: 1073 PTRPNQVFLITYPSSIKAGEVVGLGGGQWGGKSTCVSLLQNFYQPSSGLVLLDGVPVHQY 894

Query: 524  NPSWLRGQVIGFISQEPVLFATTIMENIRFGKLDASDEEVYTAAREANAHEFISSFPDGY 583
                L  + +  + QEPVLF+ +I +NI +G    +D ++ TAA +ANAH+FI + P GY
Sbjct: 893  QHHCLHSK-MALVGQEPVLFSRSIKDNIGYGPEQYNDSDIVTAAMKANAHDFIRALPRGY 717

Query: 584  STVVGERGTTLSGGQKQRLAIARALIKQPTVLILDEATSALDAESERVVQEALDRASAGR 643
             T VGERG  LSGGQKQRLAIARAL++QP +L+LDEATSALD +SE +VQ A++  + GR
Sbjct: 716  DTSVGERGLLLSGGQKQRLAIARALVRQPAILLLDEATSALDTQSESLVQSAINECTRGR 537

Query: 644  TVLVIAHRLSTVRAAHSIIVMANGQVCEAGTHEELLKKGGLYSELIRRQTLDASLTSTPP 703
            TV++IAHRL+TV  A  ++V+  G+V E G+   LLK GG+++ L R+Q +     S  P
Sbjct: 536  TVVIIAHRLTTVEKADRVLVINKGRVVEEGSPSHLLKLGGMFTSLARQQLIGTXKNSLSP 357
>22529
          Length = 312

 Score =  103 bits (258), Expect = 2e-22,   Method: Composition-based stats.
 Identities = 48/86 (55%), Positives = 64/86 (74%)
 Frame = +3

Query: 608 LIKQPTVLILDEATSALDAESERVVQEALDRASAGRTVLVIAHRLSTVRAAHSIIVMANG 667
           L++ P +L+LDEATSALD ESE+ VQ+ALD+A  GRT +VIAHRLST++ A  II    G
Sbjct: 3   LVRNPKILLLDEATSALDMESEKTVQDALDKARQGRTTIVIAHRLSTIKTADIIISFKEG 182

Query: 668 QVCEAGTHEELLKKGGLYSELIRRQT 693
           +V E GTH +L+ K G+Y +L+  QT
Sbjct: 183 KVFEQGTHADLMSKQGIYYQLVMNQT 260
>01142
          Length = 729

 Score =  103 bits (256), Expect = 4e-22,   Method: Compositional matrix adjust.
 Identities = 64/170 (37%), Positives = 100/170 (58%), Gaps = 1/170 (0%)
 Frame = -1

Query: 511 GSVTLDGHDLRTLNPSWLRGQVIGFISQEPVLFATTIMENIR-FGKLDASDEEVYTAARE 569
           GS+ +DG ++  +    LR   +  + Q+PVLF+ ++  N+  F +   SD +++TA   
Sbjct: 729 GSILIDGVNIADMGLHDLRSH-LTILPQDPVLFSGSLRMNLDPFDEY--SDSQLWTALDR 559

Query: 570 ANAHEFISSFPDGYSTVVGERGTTLSGGQKQRLAIARALIKQPTVLILDEATSALDAESE 629
           A+   F+SS P       GE G +LS GQ+Q + +AR L+++  VLILDEAT+A+D E++
Sbjct: 558 AHLRRFVSSLPAQLHFQCGEEGDSLSVGQRQLVCLARTLLRRSRVLILDEATAAVDMETD 379

Query: 630 RVVQEALDRASAGRTVLVIAHRLSTVRAAHSIIVMANGQVCEAGTHEELL 679
            ++Q  L  A +  TVL IAHRL T+     I+V+  G V E    +ELL
Sbjct: 378 ALIQNTLRSAFSVCTVLTIAHRLHTILDYDKIMVLEEGVVKEFAPPDELL 229
>15744
          Length = 1104

 Score = 54.3 bits (129), Expect(2) = 5e-16,   Method: Compositional matrix adjust.
 Identities = 30/70 (42%), Positives = 43/70 (61%)
 Frame = +3

Query: 614 VLILDEATSALDAESERVVQEALDRASAGRTVLVIAHRLSTVRAAHSIIVMANGQVCEAG 673
           VLILDEAT+A+D E++ ++Q  +    A  TVL IAHRL+T+     I+V+  GQV E  
Sbjct: 375 VLILDEATAAVDLETDDLIQATIRTEFADCTVLTIAHRLNTIMDYTRIVVLDAGQVAEFD 554

Query: 674 THEELLKKGG 683
             + LL+   
Sbjct: 555 APQALLQNSD 584

 Score = 48.5 bits (114), Expect(2) = 5e-16,   Method: Compositional matrix adjust.
 Identities = 35/117 (29%), Positives = 60/117 (51%), Gaps = 1/117 (0%)
 Frame = +1

Query: 487 LVGQSGGGKTTVASLLERFYDPEAGSVTLDGHDLRTLNPSWLRGQVIGFISQEPVLFATT 546
           +VG++G GK+++   L R  +   G +++D   +  +    LR ++   I Q+PV+F+ +
Sbjct: 1   IVGRTGAGKSSLTLALFRIIEAAGGEISIDDITISCIGLHDLRSKLT-IIPQDPVVFSGS 177

Query: 547 IMENIR-FGKLDASDEEVYTAAREANAHEFISSFPDGYSTVVGERGTTLSGGQKQRL 602
           +  N+  F K   SDEE++ A   A+   F+     G      E G  LS GQ+Q L
Sbjct: 178 LRMNLDPFDK--HSDEELWQALEHAHLKTFVQGLAAGLLHECTEGGENLSVGQRQLL 342
>30281
          Length = 821

 Score = 78.2 bits (191), Expect = 1e-14,   Method: Compositional matrix adjust.
 Identities = 52/186 (27%), Positives = 95/186 (51%), Gaps = 4/186 (2%)
 Frame = -2

Query: 533 IGFISQEPVLFATTIMENIRFGKLDASDEEVYTAAREANAHE-FISSFPDGYSTVVGERG 591
           I ++ Q+  +   T+ +NI FG      +  Y A  E    E  ++  P G  T +GE+G
Sbjct: 814 IAYVPQQAWIQNATVRDNILFGSPYIRSK--YKAILEQCELERDVAMLPGGDLTQIGEKG 641

Query: 592 TTLSGGQKQRLAIARALIKQPTVLILDEATSALDAESERVVQEALDRASA---GRTVLVI 648
             LSGGQKQR+++ARA+     V +LD+  SA+D+   + +   +   +    G T +++
Sbjct: 640 INLSGGQKQRVSVARAVYSDSDVYLLDDPLSAVDSHVGKAIFSKVIGPNGLLRGTTRVLV 461

Query: 649 AHRLSTVRAAHSIIVMANGQVCEAGTHEELLKKGGLYSELIRRQTLDASLTSTPPAEKPE 708
            H +  +     I+V+ +G++ E G++EEL+   G ++  ++       LT     E+ E
Sbjct: 460 THGVHWLPMVDEILVLMDGKISERGSYEELVSHDGPFAHFLK-----TYLTEVFEVEEQE 296

Query: 709 DPKSCQ 714
           DP+  +
Sbjct: 295 DPEIAE 278
>32946
          Length = 483

 Score = 65.5 bits (158), Expect = 8e-11,   Method: Compositional matrix adjust.
 Identities = 48/147 (32%), Positives = 79/147 (53%), Gaps = 2/147 (1%)
 Frame = -3

Query: 471 VLKDFTLKLPSGKIVALVGQSGGGKTTVASLLERF-YDPEAGSVTLDGHDLRTLNPSWLR 529
           VLK     +  GK    VG++G GK+++ + L R  Y+   GS+ +D  D   +    LR
Sbjct: 424 VLKSLNFTMNQGKSWH-VGRTGAGKSSLINALFRLSYN--DGSILIDKRDTEEIGLHDLR 254

Query: 530 GQVIGFISQEPVLFATTIMENIR-FGKLDASDEEVYTAAREANAHEFISSFPDGYSTVVG 588
            + I  I QEPVLF+ TI  N+  F +    D +++ A  E +  + +S  P G  + V 
Sbjct: 253 SK-ISIIPQEPVLFSGTIRYNLDPFEQF--PDSKLWQALEEVHLKDEVSELPMGLQSNVS 83

Query: 589 ERGTTLSGGQKQRLAIARALIKQPTVL 615
           E G+  S GQ+Q + +ARA++++  +L
Sbjct: 82  EGGSNFSVGQRQLVCLARAILRENRIL 2
>19777
          Length = 671

 Score = 55.5 bits (132), Expect = 7e-08,   Method: Compositional matrix adjust.
 Identities = 53/221 (23%), Positives = 97/221 (43%), Gaps = 6/221 (2%)
 Frame = -1

Query: 453 SITFQNVTFSYPCRPGFNVLKDFTLKLPSGKIVALVGQSGGGKTTVASLLERFYDPEAGS 512
           + + ++VT+  P +    + +D +LKL SG  + + G SG GKT++  ++   +    G 
Sbjct: 641 AFSIESVTYG-PPKSSHVLCRDLSLKLHSGTSILVTGDSGCGKTSLLRVIAGLWKSSTGY 465

Query: 513 VTLDGHDLRTLN--PSWLRGQVIGFISQEPVLFATTIMENIRFGKLDAS----DEEVYTA 566
           V       R +   PS L      ++ Q+P L   ++ + I F   +A     D+++Y  
Sbjct: 464 VD------RIVEQIPSELL-----YLPQKPYLTTGSLRDQILFPSTEADVVPDDDKMYRY 318

Query: 567 AREANAHEFISSFPDGYSTVVGERGTTLSGGQKQRLAIARALIKQPTVLILDEATSALDA 626
              A  ++ +         +        S G+ QRL+  R    +P   +LDEATS +  
Sbjct: 317 LSLAGLNQLLERLGGLDVNMDWNWYDEXSPGEMQRLSFVRXFFHKPRFALLDEATSQVSQ 138

Query: 627 ESERVVQEALDRASAGRTVLVIAHRLSTVRAAHSIIVMANG 667
           E E  +     +     T+L I HR  ++R  H + +  +G
Sbjct: 137 EMEGTLYLQCQKLHI--TLLSIGHR-DSIRPYHPLSLHFHG 24
>12308
          Length = 698

 Score = 52.4 bits (124), Expect = 7e-07,   Method: Compositional matrix adjust.
 Identities = 45/183 (24%), Positives = 84/183 (45%), Gaps = 7/183 (3%)
 Frame = -3

Query: 454 ITFQNVTFSYPCRPGFNVLKDFTLKLPSGKIVALVGQSGGGKTTVASLLERFYDPEAGSV 513
           I F  V    P   G  ++ + + ++ +G  V + G +G GK+++  +L   +    GS+
Sbjct: 537 IKFDKVPLVTPN--GDVLIPELSFEVKAGMNVLVCGPNGCGKSSLFRILGELWPLFGGSL 364

Query: 514 TLDGHDLRTLNPSWLRGQVIGFISQEPVLFATTIMENIRFGKLDASDEEVYTAAREANAH 573
           T          P   +G++  +I Q P +   T+ + + +   D+ +E++    R+    
Sbjct: 363 T---------KPE--KGKLF-YIPQRPYMTVGTLRDQVTYP--DSHEEQLRKGTRDEELA 226

Query: 574 EFISSFP-------DGYSTVVGERGTTLSGGQKQRLAIARALIKQPTVLILDEATSALDA 626
           + +           +G    V +    LSGG+KQR+A+AR    +P   ILDE TSA+  
Sbjct: 225 DILGKVQLDYVLQREGGWDAVQDWMDVLSGGEKQRIAMARLFYHKPQFAILDECTSAVSV 46

Query: 627 ESE 629
           + E
Sbjct: 45  DVE 37
>22801
          Length = 753

 Score = 45.4 bits (106), Expect = 7e-05,   Method: Compositional matrix adjust.
 Identities = 24/66 (36%), Positives = 40/66 (60%)
 Frame = -1

Query: 594 LSGGQKQRLAIARALIKQPTVLILDEATSALDAESERVVQEALDRASAGRTVLVIAHRLS 653
           LSGGQ+ R+A+A    + P VL+LDE T+ LD ES   + +A+   + G  V++++H   
Sbjct: 732 LSGGQRARVALAELSCRAPDVLVLDEPTNNLDIESIDALADAIKNFTGG--VIIVSHDER 559

Query: 654 TVRAAH 659
            +R  +
Sbjct: 558 LIRDTN 541
>03538
          Length = 1974

 Score = 45.4 bits (106), Expect = 8e-05,   Method: Compositional matrix adjust.
 Identities = 24/66 (36%), Positives = 40/66 (60%)
 Frame = -1

Query: 594  LSGGQKQRLAIARALIKQPTVLILDEATSALDAESERVVQEALDRASAGRTVLVIAHRLS 653
            LSGGQ+ R+A+A    + P VL+LDE T+ LD ES   + +A+   + G  V++++H   
Sbjct: 1725 LSGGQRARVALAELSCRAPDVLVLDEPTNNLDIESIDALADAIKNFTGG--VIIVSHDER 1552

Query: 654  TVRAAH 659
             +R  +
Sbjct: 1551 LIRDTN 1534
>19618
          Length = 974

 Score = 44.3 bits (103), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 25/75 (33%), Positives = 40/75 (53%)
 Frame = +2

Query: 594 LSGGQKQRLAIARALIKQPTVLILDEATSALDAESERVVQEALDRASAGRTVLVIAHRLS 653
           LSGG+KQR+A+AR    +P   ILDE TSA+  + E  +         G T+  ++HR  
Sbjct: 197 LSGGEKQRIAMARLFYHKPQFAILDECTSAVSVDVEGKMYSYC--REVGITLFTVSHR-K 367

Query: 654 TVRAAHSIIVMANGQ 668
           ++   H   +  +G+
Sbjct: 368 SLWVHHDYYLQFDGR 412
>27295
          Length = 384

 Score = 39.3 bits (90), Expect = 0.006,   Method: Composition-based stats.
 Identities = 23/62 (37%), Positives = 39/62 (62%), Gaps = 1/62 (1%)
 Frame = +1

Query: 493 GGKTTVASLLERFYDPEAGSVTLDGHDLRTLNPSWLRGQVIGFISQEPVLFAT-TIMENI 551
           GGKTT  S+L  F  P +G+  ++G+D+RT + + +R   +G   Q  +LF T T+ E++
Sbjct: 1   GGKTTTMSMLTGFIPPTSGTAFVNGYDIRT-DINNVRSN-LGLCPQHNILFDTLTVDEHL 174

Query: 552 RF 553
           +F
Sbjct: 175 QF 180
>20290
          Length = 1550

 Score = 38.9 bits (89), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 28/111 (25%), Positives = 52/111 (46%), Gaps = 5/111 (4%)
 Frame = +3

Query: 563  VYTAAREANAH-EFISSF--PDGYSTVVGERGTTLSGGQKQRLAIARALIKQPTVLILDE 619
            ++   R+A  H +F++    P     ++ +    LSGG+ QR+A+   L K   V ++DE
Sbjct: 945  LHDKIRDAYVHPQFMADVMKPMKIEEIMDQEVQNLSGGELQRVALVLCLGKPADVYLIDE 1124

Query: 620  ATSALDAESERVVQEALDRA--SAGRTVLVIAHRLSTVRAAHSIIVMANGQ 668
             ++ LD+E   V  + + R    A +T  V+ H           +++  GQ
Sbjct: 1125 PSAYLDSEQRLVAAKVIKRYILHAKKTGFVVEHDFIMATYLADRVIVIEGQ 1277
>18248
          Length = 466

 Score = 30.4 bits (67), Expect = 2.4,   Method: Composition-based stats.
 Identities = 15/42 (35%), Positives = 26/42 (61%)
 Frame = +1

Query: 584 STVVGERGTTLSGGQKQRLAIARALIKQPTVLILDEATSALD 625
           +T + ++   LSGG+ QR+A+   L K   V ++DE ++ LD
Sbjct: 340 NTSLTKKYKNLSGGELQRVALTLCLGKPADVYLIDEPSAYLD 465
>38795
          Length = 792

 Score = 30.4 bits (67), Expect = 2.9,   Method: Compositional matrix adjust.
 Identities = 23/74 (31%), Positives = 42/74 (56%)
 Frame = +1

Query: 593 TLSGGQKQRLAIARALIKQPTVLILDEATSALDAESERVVQEALDRASAGRTVLVIAHRL 652
             SGG + R+ +ARAL  +P++L+LDE T+ LD  +   ++E L   +  R +++I+H  
Sbjct: 130 NFSGGWRMRIGLARALYLRPSLLLLDEPTNHLDLNACVWLEEEL--KNYPRILVIISHSQ 303

Query: 653 STVRAAHSIIVMAN 666
             +    + I+  N
Sbjct: 304 DFLNGVCNSIIHMN 345
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|40068507|ref|NP_031791.3| collapsin response mediator
protein 1 isoform 2 [Mus musculus]
         (572 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

14768                                                                 213   2e-70
34622                                                                 159   2e-39
29305                                                                  40   0.003
>14768
          Length = 697

 Score =  213 bits (542), Expect(2) = 2e-70,   Method: Compositional matrix adjust.
 Identities = 94/161 (58%), Positives = 127/161 (78%)
 Frame = -1

Query: 322 ACGDLQVTGSGHCPYSTAQKAVGKDNFTLIPEGVNGIEERMTVVWDKAVATGKMDENQFV 381
           A  DLQVTG+ +C +   QKA+GKD+F  IP GVNG+E+RM+V+W+K V +GKMD  +FV
Sbjct: 487 ANNDLQVTGTDNCTFRADQKALGKDDFRSIPNGVNGVEDRMSVIWEKGVQSGKMDACRFV 308

Query: 382 AVTSTNAAKIFNLYPRKGRIAVGSDADVVIWDPDKMKTITAKSHKSTVEYNIFEGMECHG 441
           AVTS+ AAKIFN+YPRKGRIAVGSDADVV+WD ++ +TI+A++H   V++NIFEG++CHG
Sbjct: 307 AVTSSAAAKIFNIYPRKGRIAVGSDADVVVWDGNQTRTISAETHHQAVDFNIFEGLQCHG 128

Query: 442 SPLVVISQGKIVFEDGNISVSKGMGRFIPRKPFPEHLYQRV 482
            P+ VI  G +V ++G + V+KG GRFIP   FPE +Y R+
Sbjct: 127 VPVYVIXNGNVVVDNGEVKVTKGSGRFIPSPCFPEAVYGRI 5

 Score = 72.0 bits (175), Expect(2) = 2e-70,   Method: Compositional matrix adjust.
 Identities = 31/51 (60%), Positives = 41/51 (80%)
 Frame = -2

Query: 252 ITKVMSKSAADIIALARKKGPLVFGEPIAASLGTDGTHYWSKNWAKAAAFV 302
           +  +MSKS+AD+I+ +R+KG +VFGEPIAASLGTDGTH W++ W  AA  V
Sbjct: 696 VVHIMSKSSADVISASRRKGKVVFGEPIAASLGTDGTHQWNRCWRHAAGHV 544
>34622
          Length = 477

 Score =  159 bits (403), Expect = 2e-39,   Method: Compositional matrix adjust.
 Identities = 67/128 (52%), Positives = 99/128 (77%)
 Frame = -3

Query: 360 ERMTVVWDKAVATGKMDENQFVAVTSTNAAKIFNLYPRKGRIAVGSDADVVIWDPDKMKT 419
           +RM+V+W+K V  GKMD  +FVA TS NAA+I+N+YPRKGRIAVGSDADVV+WD ++ +T
Sbjct: 475 DRMSVIWEKGVMMGKMDACRFVAATSANAARIYNIYPRKGRIAVGSDADVVVWDGNQTRT 296

Query: 420 ITAKSHKSTVEYNIFEGMECHGSPLVVISQGKIVFEDGNISVSKGMGRFIPRKPFPEHLY 479
           I+A++H   V++NIFEG++CHG P+ V+S G++V +DG + V++G+GR +      E +Y
Sbjct: 295 ISAETHHQAVDFNIFEGLQCHGVPVYVVSNGQVVVDDGQLKVTQGLGRLVSTPCNAETVY 116

Query: 480 QRVRIRSK 487
            RV+ R +
Sbjct: 115 GRVKARDQ 92
>29305
          Length = 881

 Score = 39.7 bits (91), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 18/23 (78%), Positives = 20/23 (86%)
 Frame = -3

Query: 86  ADDFFQGTKAALAGGTTMIIDHV 108
            DDF+ GTKAALAGGTTMI+D V
Sbjct: 879 CDDFYIGTKAALAGGTTMIMDFV 811
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31981999|ref|NP_742162.2| intraflagellar transport 52
homolog [Mus musculus]
         (426 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

12929                                                                 261   4e-70
04043                                                                 111   7e-25
33085                                                                  31   0.94 
09933                                                                  30   2.7  
17292                                                                  28   7.4  
>12929
          Length = 620

 Score =  261 bits (666), Expect = 4e-70,   Method: Compositional matrix adjust.
 Identities = 129/187 (68%), Positives = 151/187 (80%)
 Frame = -2

Query: 153 DEENSGNNAQALTFVYPFGATLSVMKPAVAVLSTGSVCFPLNRPILAFYHSKNQGFGKLA 212
           DEE  GNNAQAL+F+YPFGATL+VMKP+ AVLSTGSV FPLNRP+   + SK  G GKL 
Sbjct: 610 DEE--GNNAQALSFLYPFGATLNVMKPSAAVLSTGSVSFPLNRPVCGLHTSK-AGRGKLV 440

Query: 213 VLGSCHMFSDQYLDKEENSKIMDVVFQWLTTGDIHLNQIDAEDPEISDYTMVPDTATLSE 272
           VLGS HMFSDQYLDKEEN KI+DV+ Q+LTT +I LN IDAEDPEISDY  +PD A LSE
Sbjct: 439 VLGSTHMFSDQYLDKEENGKILDVLIQFLTTDEIKLNVIDAEDPEISDYNQLPDVARLSE 260

Query: 273 QLRVCLQEGDENPRDFTTLFDLSIYQLDTTCLPKVIKAHEELNVKHEPLQLVQPQFEMPL 332
           QL+ CLQE D+ PRD T+LFD S+++LDT+ + K IKA E+L+ KHEPL L+ PQFE PL
Sbjct: 259 QLKTCLQESDDIPRDITSLFDNSLFRLDTSLVSKSIKAFEQLSCKHEPLTLITPQFETPL 80

Query: 333 PALQPAV 339
           P LQPAV
Sbjct: 79  PPLQPAV 59
>04043
          Length = 643

 Score =  111 bits (277), Expect = 7e-25,   Method: Compositional matrix adjust.
 Identities = 50/64 (78%), Positives = 58/64 (90%)
 Frame = +1

Query: 361 FSSEKARLAQITNKCTDEDLEFYVRKCGDILGVTSKLPKDQQDAKHILEHIFFQVVEFKK 420
           FSSEK R+AQITNKCTD+DLE+YVR+CGDILGVT  LP+D + AKHILEHIF Q+VEFKK
Sbjct: 1   FSSEKVRVAQITNKCTDDDLEYYVRECGDILGVTHNLPQDNRTAKHILEHIFTQIVEFKK 180

Query: 421 LNQE 424
           LNQ+
Sbjct: 181 LNQD 192
>33085
          Length = 496

 Score = 31.2 bits (69), Expect = 0.94,   Method: Compositional matrix adjust.
 Identities = 16/61 (26%), Positives = 30/61 (49%), Gaps = 6/61 (9%)
 Frame = +2

Query: 178 KPAVAVLSTGSVC------FPLNRPILAFYHSKNQGFGKLAVLGSCHMFSDQYLDKEENS 231
           K  V ++S  + C      FP      + +HSK+ G+ ++ V  S H++ +Q  D ++  
Sbjct: 248 KATVHIVSGSAGCQENHDEFPQIEKDYSAFHSKDYGYSRMTVYNSTHLYFEQVSDDQKRK 427

Query: 232 K 232
           K
Sbjct: 428 K 430
>09933
          Length = 2033

 Score = 29.6 bits (65), Expect = 2.7,   Method: Compositional matrix adjust.
 Identities = 13/49 (26%), Positives = 25/49 (51%)
 Frame = -3

Query: 197  ILAFYHSKNQGFGKLAVLGSCHMFSDQYLDKEENSKIMDVVFQWLTTGD 245
            ++ F+ +   G+  +  L  CH+ +  YL+  E   +MD   +W+T  D
Sbjct: 1395 LMRFFFTCKSGYDTVDWLAKCHLNALAYLEPPETYPVMD---KWVTEND 1258
>17292
          Length = 477

 Score = 28.1 bits (61), Expect = 7.4,   Method: Compositional matrix adjust.
 Identities = 15/49 (30%), Positives = 26/49 (53%), Gaps = 4/49 (8%)
 Frame = -1

Query: 97  TNINFLLEEY----GIMVNNDAVVRNVYYKYFHPKEALVSDGVLNREIS 141
           T I F++  Y     +++ NDA+ RN+ YK ++ KE  +    L   +S
Sbjct: 381 TYITFVIRCYHASRSLLIRNDAIQRNI-YKCYNCKETFIHSNTLVNSVS 238
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|84794597|ref|NP_077779.2| protein phosphatase 3,
regulatory subunit B, alpha isoform (calcineurin B, type I) [Mus
musculus]
         (170 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

26019                                                                 254   4e-70
14594                                                                  83   5e-17
14945                                                                  37   4e-08
22063                                                                  37   4e-08
16289                                                                  54   4e-08
14366                                                                  52   1e-07
05237                                                                  51   3e-07
17484                                                                  50   4e-07
07678                                                                  42   1e-04
01019                                                                  42   1e-04
32088                                                                  39   0.001
01773                                                                  37   0.004
00167                                                                  36   0.009
08108                                                                  36   0.009
08380                                                                  35   0.022
38338                                                                  34   0.025
15966                                                                  33   0.040
01401                                                                  33   0.043
04697                                                                  33   0.063
14601                                                                  32   0.18 
03732                                                                  32   0.19 
32153                                                                  31   0.32 
16255                                                                  30   0.40 
26849                                                                  30   0.41 
07385                                                                  30   0.45 
00992                                                                  30   0.55 
02929                                                                  30   0.64 
05230                                                                  29   0.86 
01491                                                                  29   0.93 
19912                                                                  29   1.0  
19745                                                                  28   1.3  
04117                                                                  28   1.3  
22273                                                                  28   1.9  
33397                                                                  28   2.7  
04643                                                                  27   5.9  
20170                                                                  26   7.7  
27864                                                                  26   8.1  
13551                                                                  26   8.3  
04067                                                                  26   9.7  
>26019
          Length = 1561

 Score =  254 bits (648), Expect(2) = 4e-70,   Method: Compositional matrix adjust.
 Identities = 128/150 (85%), Positives = 137/150 (91%)
 Frame = +2

Query: 21  KRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGVS 80
           +RLGKRF+KLDLDNSGSLS++EFMSLPELQQNPLVQRVIDIFDTDGNGEVDFKEFIEG+S
Sbjct: 98  QRLGKRFRKLDLDNSGSLSIDEFMSLPELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGIS 277

Query: 81  QFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINA 140
           QFSVKGDKE KLRFAF+IYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDK   + 
Sbjct: 278 QFSVKGDKESKLRFAFKIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKP-SSM 454

Query: 141 DKDGDGRISFEEFCAVVGGLDIHKKMVVDV 170
                  ISFEEFCAVVG +D+HKKMVVDV
Sbjct: 455 RTPTVMEISFEEFCAVVGTMDVHKKMVVDV 544

 Score = 27.3 bits (59), Expect(2) = 4e-70,   Method: Compositional matrix adjust.
 Identities = 11/20 (55%), Positives = 13/20 (65%)
 Frame = +3

Query: 8  PLEMCSHFDADEIKRLGKRF 27
           +E+CS FD DEIK L   F
Sbjct: 60 AMELCSTFDVDEIKDLANDF 119
>14594
          Length = 1014

 Score = 83.2 bits (204), Expect = 5e-17,   Method: Compositional matrix adjust.
 Identities = 50/144 (34%), Positives = 82/144 (56%), Gaps = 4/144 (2%)
 Frame = +3

Query: 18  DEIKRLGKRFKKLDLDNSGSLSVEEFMS-LPELQQNPL---VQRVIDIFDTDGNGEVDFK 73
           +++    + F   D D  G+++  E  + +  L QNP    +Q +I+  D DGNG +DF+
Sbjct: 432 EQVAEFKEAFSLFDKDGDGTITTSELGTVMRSLGQNPTENELQDMINEVDADGNGTIDFE 611

Query: 74  EFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIV 133
           EF+  +++     D E++LR AFR++D D +GYIS  EL  V+      NL +    + V
Sbjct: 612 EFLHMMARKMKDTDCEEELREAFRVFDKDGNGYISAAELRHVM-----TNLGEKLTDEEV 776

Query: 134 DKTIINADKDGDGRISFEEFCAVV 157
           D+ I  AD DGDG +++EEF  ++
Sbjct: 777 DEMIKEADLDGDGMVNYEEFVTMM 848
>14945
          Length = 1337

 Score = 37.0 bits (84), Expect(2) = 4e-08,   Method: Compositional matrix adjust.
 Identities = 24/63 (38%), Positives = 37/63 (58%)
 Frame = +2

Query: 101 MDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGL 160
           M K   IS   L +V K + G NL D +LQ+++D+    AD+DGDG I+ EEF  ++   
Sbjct: 365 MMKPAKISFRNLKRVAKEL-GENLTDEELQEMIDE----ADRDGDGEINQEEFLRIMKKT 529

Query: 161 DIH 163
            ++
Sbjct: 530 SLY 538

 Score = 36.2 bits (82), Expect(2) = 4e-08,   Method: Compositional matrix adjust.
 Identities = 23/83 (27%), Positives = 47/83 (56%), Gaps = 4/83 (4%)
 Frame = +1

Query: 27  FKKLDLDNSGSLSVEEF-MSLPELQQNPL---VQRVIDIFDTDGNGEVDFKEFIEGVSQF 82
           F   D D SG++  +E  +++  L   P    ++++I   D +G G +DF +F+  ++Q 
Sbjct: 130 FDLFDADGSGTIDAKELKVAMRALGFEPKKEEIKKMIAEIDKEGTGTIDFNDFLTIMTQK 309

Query: 83  SVKGDKEQKLRFAFRIYDMDKDG 105
             + D ++++  AFR++D D+ G
Sbjct: 310 MSEKDAKEEILKAFRLFDDDETG 378
>22063
          Length = 688

 Score = 36.6 bits (83), Expect(2) = 4e-08,   Method: Compositional matrix adjust.
 Identities = 23/83 (27%), Positives = 47/83 (56%), Gaps = 4/83 (4%)
 Frame = +3

Query: 27  FKKLDLDNSGSLSVEEF-MSLPELQQNPL---VQRVIDIFDTDGNGEVDFKEFIEGVSQF 82
           F   D D SG++  +E  +++  L   P    ++++I   D +G G +DF +F+  ++Q 
Sbjct: 189 FDLFDADGSGTIDAKELKVAMRALGFEPKKEEIKKMIAEIDKEGTGTIDFNDFLTIMTQK 368

Query: 83  SVKGDKEQKLRFAFRIYDMDKDG 105
             + D ++++  AFR++D D+ G
Sbjct: 369 MSEKDAKEEILKAFRLFDDDETG 437

 Score = 36.6 bits (83), Expect(2) = 4e-08,   Method: Compositional matrix adjust.
 Identities = 24/57 (42%), Positives = 35/57 (61%)
 Frame = +1

Query: 101 MDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVV 157
           M K   IS   L +V K + G NL D +LQ+++D+    AD+DGDG I+ EEF  ++
Sbjct: 424 MMKRAKISFRNLKRVAKEL-GENLTDEELQEMIDE----ADRDGDGEINQEEFLRIM 579
>16289
          Length = 522

 Score = 53.5 bits (127), Expect = 4e-08,   Method: Compositional matrix adjust.
 Identities = 25/58 (43%), Positives = 36/58 (62%)
 Frame = +3

Query: 111 ELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLDIHKKMVV 168
           EL  +L MMVG N+   QL  I ++TI+ AD    G+ISFE+FC  +   D+ +KM +
Sbjct: 3   ELLSILHMMVGANISQDQLVSIAERTILEADLCCQGKISFEDFCKALERTDVDQKMSI 176
>14366
          Length = 499

 Score = 52.0 bits (123), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 32/96 (33%), Positives = 51/96 (53%)
 Frame = -3

Query: 62  FDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVG 121
           F+  G   +  +E I  V+++    +    LR AFRI+D + +G I+  EL  VL  + G
Sbjct: 335 FENRGKRTLTLQEVIAIVTKYEFAPETSDNLREAFRIFDKEGNGMINAAELRHVLTHL-G 159

Query: 122 NNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVV 157
             L D +    VD+ I  AD  GDG++S+ +F  V+
Sbjct: 158 EKLSDEE----VDEMIREADISGDGQVSYNDFVKVM 63
>05237
          Length = 472

 Score = 50.8 bits (120), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 29/71 (40%), Positives = 45/71 (63%)
 Frame = +3

Query: 87  DKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDG 146
           D + +LR AFR++D D +G+IS  EL  V+  + G  L D +    VD+ I  AD DGDG
Sbjct: 18  DTDDELREAFRVFDKDGNGFISASELRHVMTNL-GEKLTDEE----VDEMIREADIDGDG 182

Query: 147 RISFEEFCAVV 157
           ++++EEF  ++
Sbjct: 183 QVNYEEFVKMM 215

 Score = 27.7 bits (60), Expect = 2.8,   Method: Compositional matrix adjust.
 Identities = 18/58 (31%), Positives = 31/58 (53%), Gaps = 4/58 (6%)
 Frame = +3

Query: 23 LGKRFKKLDLDNSGSLSVEEF----MSLPELQQNPLVQRVIDIFDTDGNGEVDFKEFI 76
          L + F+  D D +G +S  E      +L E   +  V  +I   D DG+G+V+++EF+
Sbjct: 33 LREAFRVFDKDGNGFISASELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFV 206
>17484
          Length = 471

 Score = 50.1 bits (118), Expect = 4e-07,   Method: Compositional matrix adjust.
 Identities = 29/73 (39%), Positives = 44/73 (60%)
 Frame = -3

Query: 87  DKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDG 146
           +K++++R AFR +D + DG IS  EL Q +  M G  L D  ++ I    I + DKDGDG
Sbjct: 280 EKDKEMRDAFRAFDQNGDGVISISELRQAMAKM-GQKLSDADVESI----IRDVDKDGDG 116

Query: 147 RISFEEFCAVVGG 159
            +++EEF   + G
Sbjct: 115 FVNYEEFTKFIAG 77
>07678
          Length = 958

 Score = 42.0 bits (97), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 32/105 (30%), Positives = 51/105 (48%), Gaps = 3/105 (2%)
 Frame = +1

Query: 55  VQRVIDIFDTDGNGEVDFKEFIEGVSQFSV---KGDKEQKLRFAFRIYDMDKDGYISNGE 111
           + R   I D DGN  +DFKEF +G+++F +   +GD  Q++   F  +D D+ G I   E
Sbjct: 325 LARKFKIMDDDGNRSLDFKEFKKGITEFGLTQFEGDVIQEM---FTCFDKDZSGTIDFDE 495

Query: 112 LFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAV 156
               L+  +    KD     ++ +     DK GDG ++ E+   V
Sbjct: 496 FLVKLRPPMSQMRKD-----LIQRAFQKLDKTGDGVVTVEDLKGV 615

 Score = 39.7 bits (91), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 46/165 (27%), Positives = 78/165 (47%), Gaps = 16/165 (9%)
 Frame = +1

Query: 5   ASYPLE----MCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEF------MSLPELQQNPL 54
           A+ P+E     C    A  IK L ++FK +D D + SL  +EF        L + + + +
Sbjct: 259 ATDPVEKLRLACLARGAAGIKGLARKFKIMDDDGNRSLDFKEFKKGITEFGLTQFEGD-V 435

Query: 55  VQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQ 114
           +Q +   FD D +G +DF EF+  +     +  K+   R AF+  D   DG ++  +L  
Sbjct: 436 IQEMFTCFDKDZSGTIDFDEFLVKLRPPMSQMRKDLIQR-AFQKLDKTGDGVVTVEDLKG 612

Query: 115 VL------KMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEF 153
           V       K + G   ++  L+  +D    ++  D DG+I+ EEF
Sbjct: 613 VYNVTKHPKYLNGEWTEERILRIFLDS--FDSPNDKDGKITKEEF 741
>01019
          Length = 1705

 Score = 41.6 bits (96), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 22/64 (34%), Positives = 37/64 (57%)
 Frame = +1

Query: 94  FAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEF 153
           +   ++D D +G+IS  EL  V+      NL +    + VD+ I  AD DGDG++++EEF
Sbjct: 31  WPLLVFDKDGNGFISAAELRHVM-----TNLGEKLTDEEVDEMIREADIDGDGQVNYEEF 195

Query: 154 CAVV 157
             ++
Sbjct: 196 VTMM 207
>32088
          Length = 1928

 Score = 38.9 bits (89), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 25/67 (37%), Positives = 37/67 (55%)
 Frame = +1

Query: 87  DKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDG 146
           D+  +LR  F   D D +G+IS GEL    +  VG N+   +L+ I+ K     D  GDG
Sbjct: 934 DQLTELRSVFDSIDDDNNGHISXGELDSAFRA-VGLNIPGYELRTIMSK----YDASGDG 1098

Query: 147 RISFEEF 153
           R++ +EF
Sbjct: 1099RLNMDEF 1119
>01773
          Length = 1950

 Score = 37.0 bits (84), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 39/136 (28%), Positives = 61/136 (44%), Gaps = 9/136 (6%)
 Frame = +1

Query: 27  FKKLDLDNSGSLSVEEFMSLPELQQNPLV-QRVIDIF----DTDGNGEVDFKEFIEGVSQ 81
           FK+ D +N G L ++E   L +   + L   ++ D F       G+  + F+ F +G+ Q
Sbjct: 172 FKEADKNNDGYLEIKELRELFKRNGSSLSDSQIADTFVFFDGPRGDKRITFEXFCKGLDQ 351

Query: 82  FSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQI----VDKTI 137
             +     QKL   F+  D   DGY+   EL  +L         D   Q+     V   +
Sbjct: 352 IVMF---VQKLAELFKAKDKSGDGYLDRDELKALL---------DESGQKFTADDVSAIL 495

Query: 138 INADKDGDGRISFEEF 153
            +ADK+ D +I FEEF
Sbjct: 496 KSADKNNDNKICFEEF 543
>00167
          Length = 2176

 Score = 35.8 bits (81), Expect = 0.009,   Method: Compositional matrix adjust.
 Identities = 38/153 (24%), Positives = 71/153 (46%), Gaps = 12/153 (7%)
 Frame = +3

Query: 20  IKRLGKRFKKLDLDNSGSLSVEEFM------SLPELQQNPLVQRVIDIFDTDGNGEVDFK 73
           IK +G++F+ +D +    LSV+EF+       + ++    L   V   FD DG G +DF+
Sbjct: 726 IKTIGRKFRIMDDNRDRKLSVDEFIVGCRECRIAKMTSEEL-NEVFRRFDKDGTGTLDFE 902

Query: 74  EFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQL---- 129
           EF+  +    +   + + ++ AF   D   DG I+  +L     +      ++ +L    
Sbjct: 903 EFLLALRP-KMNEFRRKLVKKAFAKMDKTGDGIITADDLVGTYDVRSHPRYQNGELTKKQ 1079

Query: 130 --QQIVDKTIINADKDGDGRISFEEFCAVVGGL 160
             Q+ +D  ++  D D DG I+  E+     G+
Sbjct: 1080VYQEFLDNFVV-GDND-DGVITMAEWIDYYSGV 1172
>08108
          Length = 818

 Score = 35.8 bits (81), Expect = 0.009,   Method: Compositional matrix adjust.
 Identities = 26/96 (27%), Positives = 43/96 (44%), Gaps = 7/96 (7%)
 Frame = +2

Query: 27  FKKLDLDNSGSLSVEEFMSLPELQQNPLV----QRVIDIFDTDGNGEVD---FKEFIEGV 79
           F   D D SGS+S  E       Q   +       +I  +D+D NG++D   F++ +EG 
Sbjct: 143 FAVFDTDGSGSISAGELGEALRAQGADITDDQTAELIKKYDSDSNGDIDTDEFRKLVEGE 322

Query: 80  SQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQV 115
           S  +    +  +    F+  D D DG I+  E+ + 
Sbjct: 323 SDVA----RLAQSALMFKSLDADGDGQITASEITEA 418

 Score = 32.7 bits (73), Expect = 0.073,   Method: Compositional matrix adjust.
 Identities = 30/128 (23%), Positives = 53/128 (41%), Gaps = 6/128 (4%)
 Frame = +2

Query: 37  SLSVEEFMSLPELQQNPLV----QRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKL 92
           SLS +      +L   PL     Q    +FDTDG+G +   E  E +         +Q  
Sbjct: 65  SLSRQSHRHSIQLTMAPLTDAECQTAFAVFDTDGSGSISAGELGEALRAQGADITDDQTA 244

Query: 93  RFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTII--NADKDGDGRISF 150
               + YD D +G I   E  ++++        ++ + ++    ++  + D DGDG+I+ 
Sbjct: 245 EL-IKKYDSDSNGDIDTDEFRKLVE-------GESDVARLAQSALMFKSLDADGDGQITA 400

Query: 151 EEFCAVVG 158
            E     G
Sbjct: 401 SEITEAQG 424
>08380
          Length = 1236

 Score = 34.7 bits (78), Expect = 0.022,   Method: Compositional matrix adjust.
 Identities = 44/158 (27%), Positives = 67/158 (42%), Gaps = 27/158 (17%)
 Frame = -1

Query: 29  KLDLDNSGSLSVEEFMSLP----ELQQNPLVQRVIDIF---DTDGNGEVDFKEFI----- 76
           K+D D  G LSV E  +      E   +   Q   +IF   D D NG+V +KE+      
Sbjct: 861 KVDSDKDGKLSVAELEAWVKDKMEEHFSEATQENEEIFKHLDPDNNGKVHWKEYYVHFLL 682

Query: 77  ------EGVSQFSVKGD--------KEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGN 122
                 +  S+  V  D        KE+ +R+ FR  D D  G   + EL +   M   +
Sbjct: 681 AKGYKQDVASRHVVDYDZIQLDPDAKEEIIRYKFRWSDAD--GEPMDNELTREEFMSFRH 508

Query: 123 -NLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGG 159
               +  L  +V+  +   D +GDG ++ EEF A+  G
Sbjct: 507 PEQSEKTLNNMVNGILGGIDTNGDGVVTEEEFSALPPG 394
>38338
          Length = 463

 Score = 34.3 bits (77), Expect = 0.025,   Method: Compositional matrix adjust.
 Identities = 20/66 (30%), Positives = 33/66 (50%), Gaps = 4/66 (6%)
 Frame = -2

Query: 11  MCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMS-LPELQQNPL---VQRVIDIFDTDG 66
           M      ++I    + F   D D  G+++ +E  + +  L QNP    +Q +I+  D DG
Sbjct: 198 MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADG 19

Query: 67  NGEVDF 72
           NG +DF
Sbjct: 18  NGTIDF 1
>15966
          Length = 362

 Score = 33.5 bits (75), Expect = 0.040,   Method: Compositional matrix adjust.
 Identities = 28/88 (31%), Positives = 41/88 (46%)
 Frame = +2

Query: 66  GNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLK 125
           G+  + F+EF +G+ Q  +     QKL   F+  D   DGY+   EL  +L         
Sbjct: 71  GDKRITFEEFCKGLDQIVMF---VQKLAELFKAKDKSGDGYLDRDELKALLDESGQKFTA 241

Query: 126 DTQLQQIVDKTIINADKDGDGRISFEEF 153
           D      V   + +ADK+ D +I FEEF
Sbjct: 242 DD-----VSAILKSADKNNDNKICFEEF 310
>01401
          Length = 1454

 Score = 33.5 bits (75), Expect = 0.043,   Method: Compositional matrix adjust.
 Identities = 20/57 (35%), Positives = 32/57 (56%), Gaps = 6/57 (10%)
 Frame = +1

Query: 27  FKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVIDIFD------TDGNGEVDFKEFIE 77
           F++LD DNSGSL+ EE M+  +  +  L  R   I D       D + ++D+ EF++
Sbjct: 280 FRQLDKDNSGSLTREEIMAAVQ-SEGELKLRAAKISDLLVAWHKDADQKLDYNEFVQ 447
>04697
          Length = 559

 Score = 33.1 bits (74), Expect = 0.063,   Method: Compositional matrix adjust.
 Identities = 24/81 (29%), Positives = 37/81 (45%), Gaps = 4/81 (4%)
 Frame = +1

Query: 1   MGNEASYPLEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEE----FMSLPELQQNPLVQ 56
           MG +     E   +F  DEI +  KRFK LD  N G ++V +    F  + E      + 
Sbjct: 301 MGLDIKQTSESHLNFTKDEINQYVKRFKSLDYQNKGFVTVNDLRRYFKKMGEKVTEDQLH 480

Query: 57  RVIDIFDTDGNGEVDFKEFIE 77
            ++   D   N +VD  EF++
Sbjct: 481 DILSEVDLSRNAQVDLGEFLQ 543
>14601
          Length = 472

 Score = 31.6 bits (70), Expect = 0.18,   Method: Compositional matrix adjust.
 Identities = 18/64 (28%), Positives = 32/64 (50%), Gaps = 5/64 (7%)
 Frame = +3

Query: 96  FRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTII-----NADKDGDGRISF 150
           F+  D ++D  +S  E+   L+    ++ +   + Q+   T++     + DKD DG IS 
Sbjct: 18  FKQIDTNEDSLLSQDEVSAYLQQQRKSDPRAPPMNQMQHSTVVSQIFEHEDKDKDGFISH 197

Query: 151 EEFC 154
           EEF 
Sbjct: 198 EEFS 209
>03732
          Length = 1114

 Score = 31.6 bits (70), Expect = 0.19,   Method: Compositional matrix adjust.
 Identities = 26/107 (24%), Positives = 44/107 (41%), Gaps = 29/107 (27%)
 Frame = -1

Query: 30  LDLDNSGSLSVEEFMSLPELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSV----- 84
            D DNSG+++ +EF +L +   +   Q     +D D +G +D  E    ++ F       
Sbjct: 964 FDRDNSGTINFQEFQALWKYVTD--WQNCFRSYDRDNSGSIDRNELKNALTGFGYRLSDR 791

Query: 85  -------KGDKE-----------------QKLRFAFRIYDMDKDGYI 107
                  K D++                 Q L  +FR +D D+DG+I
Sbjct: 790 FFDVLVKKFDRQGKGTVAFDDFIQCCVVLQTLTTSFRTHDQDQDGWI 650
>32153
          Length = 471

 Score = 30.8 bits (68), Expect = 0.32,   Method: Compositional matrix adjust.
 Identities = 24/79 (30%), Positives = 39/79 (49%), Gaps = 5/79 (6%)
 Frame = -1

Query: 84  VKGDKEQKLRFAFRIYDMDKDGYISNGELFQ-----VLKMMVGNNLKDTQLQQIVDKTII 138
           ++   ++K    F   D D DG I+  EL Q     +LKMM      +  L  ++   + 
Sbjct: 444 LRAQYKKKYTNMFNAIDADSDGKITFNELKQNYGNKMLKMM------EPFLTIMMRMLMN 283

Query: 139 NADKDGDGRISFEEFCAVV 157
           NAD DGDG I+ +E+  ++
Sbjct: 282 NADGDGDGLITLQEWYTLM 226
>16255
          Length = 767

 Score = 30.4 bits (67), Expect = 0.40,   Method: Compositional matrix adjust.
 Identities = 14/36 (38%), Positives = 23/36 (63%)
 Frame = -2

Query: 122 NNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVV 157
            NL +    + VD+ I  AD DGDG++++EEF  ++
Sbjct: 763 TNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVTMM 656
>26849
          Length = 649

 Score = 30.4 bits (67), Expect = 0.41,   Method: Compositional matrix adjust.
 Identities = 26/87 (29%), Positives = 38/87 (43%), Gaps = 12/87 (13%)
 Frame = +2

Query: 7   YPLEM-CSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVIDI---- 61
           Y L + C       I  L + F+ +D D S  LS+EEF       +  ++   IDI    
Sbjct: 122 YKLRLQCLSRGPTGILGLARAFRVMDKDGSKVLSLEEF-------KKGILDMHIDINEAD 280

Query: 62  -------FDTDGNGEVDFKEFIEGVSQ 81
                  FD DGNG ++  EF+  V+ 
Sbjct: 281 IEDMFYRFDNDGNGTINMTEFLLKVAS 361
>07385
          Length = 1292

 Score = 30.0 bits (66), Expect = 0.45,   Method: Compositional matrix adjust.
 Identities = 16/53 (30%), Positives = 27/53 (50%), Gaps = 4/53 (7%)
 Frame = +3

Query: 105 GYISNGELFQVLKMMVGNNLKDTQLQQI----VDKTIINADKDGDGRISFEEF 153
           G    G      + +    L+  + Q++    VD+ I  AD DGDG++++EEF
Sbjct: 72  GSPPGGSRGWCSRRISAGQLRGARFQKLTDEEVDEMIREADIDGDGQVNYEEF 230
>00992
          Length = 1754

 Score = 30.0 bits (66), Expect = 0.55,   Method: Compositional matrix adjust.
 Identities = 15/42 (35%), Positives = 28/42 (66%), Gaps = 1/42 (2%)
 Frame = +2

Query: 68  GEVDFKEFIEGVSQFSVKGDKE-QKLRFAFRIYDMDKDGYIS 108
           GE+D+K +++ V   +++  +E Q LR+ FRI D+   GY++
Sbjct: 56  GEMDYKTYLDFV--LAMENRREPQALRYLFRILDVQHRGYLN 175
>02929
          Length = 1353

 Score = 29.6 bits (65), Expect = 0.64,   Method: Compositional matrix adjust.
 Identities = 17/57 (29%), Positives = 32/57 (56%), Gaps = 4/57 (7%)
 Frame = +2

Query: 27  FKKLDLDNSGSLSVEEFMSLPELQQNPL----VQRVIDIFDTDGNGEVDFKEFIEGV 79
           F++ D D  G L+ EEF++     + P     +  V DIFD +  G +++K+F++ +
Sbjct: 194 FRRQDKDGDGFLTEEEFVNGMMQSRFPTNRTELNAVFDIFDREKRGLIEYKDFVDAL 364

 Score = 28.9 bits (63), Expect = 0.97,   Method: Compositional matrix adjust.
 Identities = 21/64 (32%), Positives = 32/64 (50%), Gaps = 3/64 (4%)
 Frame = +2

Query: 57  RVIDIF---DTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELF 113
           RV D F   D DG+G +  +EF+ G+ Q     ++ + L   F I+D +K G I   +  
Sbjct: 179 RVTDFFRRQDKDGDGFLTEEEFVNGMMQSRFPTNRTE-LNAVFDIFDREKRGLIEYKDFV 355

Query: 114 QVLK 117
             LK
Sbjct: 356 DALK 367
>05230
          Length = 843

 Score = 29.3 bits (64), Expect = 0.86,   Method: Compositional matrix adjust.
 Identities = 21/83 (25%), Positives = 44/83 (53%), Gaps = 5/83 (6%)
 Frame = -2

Query: 38  LSVEEFMSL-----PELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKL 92
           L +EE++S+      +++ N + +++   FDTDG+G    ++ IEG+    +    +  L
Sbjct: 698 LRMEEYISIMSDASVDMKTN-MWRKLFAQFDTDGSGWASREDVIEGLENIGITITPD--L 528

Query: 93  RFAFRIYDMDKDGYISNGELFQV 115
           R   +  D +KDG I+  +  ++
Sbjct: 527 RAKIKAMDGNKDGKINYADFLRM 459
>01491
          Length = 1707

 Score = 29.3 bits (64), Expect = 0.93,   Method: Compositional matrix adjust.
 Identities = 18/54 (33%), Positives = 31/54 (57%), Gaps = 5/54 (9%)
 Frame = +1

Query: 27  FKKLDLDNSGSLSVEEFMSL-----PELQQNPLVQRVIDIFDTDGNGEVDFKEF 75
           F+ LD  N G + VE+   L      +L ++ +   +++  DTDG+G VD++EF
Sbjct: 364 FRVLDKGNKGVIPVEDLRWLLKSLGDDLTEDEIEDMIVET-DTDGSGTVDYEEF 522
>19912
          Length = 865

 Score = 28.9 bits (63), Expect = 1.0,   Method: Compositional matrix adjust.
 Identities = 20/78 (25%), Positives = 42/78 (53%), Gaps = 4/78 (5%)
 Frame = +2

Query: 9   LEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPL----VQRVIDIFDT 64
           +++ ++ D++ + RL   F K D + + S++ ++F         PL    V  ++D  D 
Sbjct: 635 VKLMAYIDSNNL-RLVDFFNKFDKEGTMSITRDQFRQGLTEASIPLAGDEVDFLLDELDR 811

Query: 65  DGNGEVDFKEFIEGVSQF 82
           DG+GE+++ E + G + F
Sbjct: 812 DGDGEINYSELVIGHTDF 865
>19745
          Length = 1014

 Score = 28.5 bits (62), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 17/41 (41%), Positives = 26/41 (63%), Gaps = 1/41 (2%)
 Frame = -1

Query: 37  SLSVEEFMSLPELQQNP-LVQRVIDIFDTDGNGEVDFKEFI 76
           S+SVE+     +LQ++P L QRV    DT+G+G V  +E +
Sbjct: 927 SISVEDLSR--DLQRDPALAQRVARHLDTNGDGFVAVREVL 811
>04117
          Length = 697

 Score = 28.5 bits (62), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 18/62 (29%), Positives = 26/62 (41%)
 Frame = -1

Query: 11  MCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVIDIFDTDGNGEV 70
           MC++        L   FK+          V  F  +P L ++ LVQ     F + GNG V
Sbjct: 319 MCTYVH*PRTSVLYAHFKQ------KQAWVNIFCKIPGLFKDTLVQDFFKYFSSPGNGHV 158

Query: 71  DF 72
           +F
Sbjct: 157 NF 152
>22273
          Length = 297

 Score = 28.1 bits (61), Expect = 1.9,   Method: Compositional matrix adjust.
 Identities = 12/25 (48%), Positives = 19/25 (76%)
 Frame = +1

Query: 133 VDKTIINADKDGDGRISFEEFCAVV 157
           VD+ I  AD DGDG++++EEF  ++
Sbjct: 1   VDEMIREADIDGDGQVNYEEFVKMM 75
>33397
          Length = 1723

 Score = 27.7 bits (60), Expect = 2.7,   Method: Compositional matrix adjust.
 Identities = 29/129 (22%), Positives = 52/129 (40%), Gaps = 5/129 (3%)
 Frame = +3

Query: 32  LDNSGSLSVEEFMSLPELQQNPL--VQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKE 89
           L   G +S  +++ L  +   P    +    +FD +G+GE+D +EF        V+G   
Sbjct: 123 LGEHGLISFSDYIFLLTVLSTPPRNFEIAFRMFDINGDGELDLEEFNR------VQGVIR 284

Query: 90  QKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGD---G 146
            +     R  D    G + +G    +L    G N K    +++  K  ++  +       
Sbjct: 285 NQTHVGARHRDHAVTGSVDHGLSSSLLSYFFGKNGK----KKLTHKEFLDFQRQLQREIN 452

Query: 147 RISFEEFCA 155
           RI FE +C 
Sbjct: 453 RIEFERYCG 479
>04643
          Length = 1881

 Score = 26.6 bits (57), Expect = 5.9,   Method: Compositional matrix adjust.
 Identities = 14/47 (29%), Positives = 26/47 (55%), Gaps = 5/47 (10%)
 Frame = +2

Query: 35 SGSLSVEEFMS-LPELQQNPLVQRVIDIF----DTDGNGEVDFKEFI 76
          SG L  +E  + +  L  + + +  +D      D DGNG++++KEF+
Sbjct: 2  SGCLCADEIKAHVRALTGDDMSEEALDNLVSKSDADGNGKINYKEFL 142
>20170
          Length = 470

 Score = 26.2 bits (56), Expect = 7.7,   Method: Compositional matrix adjust.
 Identities = 9/15 (60%), Positives = 13/15 (86%)
 Frame = -3

Query: 140 ADKDGDGRISFEEFC 154
           ADKD DG++S +E+C
Sbjct: 399 ADKDNDGQVSVDEWC 355
>27864
          Length = 343

 Score = 25.8 bits (55), Expect = 8.1,   Method: Compositional matrix adjust.
 Identities = 14/45 (31%), Positives = 24/45 (53%)
 Frame = +1

Query: 30  LDLDNSGSLSVEEFMSLPELQQNPLVQRVIDIFDTDGNGEVDFKE 74
            D DNSG+++ +EF +L +   +   Q     +D D +G +D  E
Sbjct: 151 FDRDNSGTINFQEFQALWKYVTD--WQNCFRSYDRDNSGSIDRNE 279
>13551
          Length = 529

 Score = 25.8 bits (55), Expect = 8.3,   Method: Compositional matrix adjust.
 Identities = 11/24 (45%), Positives = 16/24 (66%)
 Frame = +1

Query: 133 VDKTIINADKDGDGRISFEEFCAV 156
           V + +   DK+ DG + FEEFCA+
Sbjct: 82  VTQWLREEDKNVDGCLDFEEFCAL 153
>04067
          Length = 1920

 Score = 25.8 bits (55), Expect = 9.7,   Method: Compositional matrix adjust.
 Identities = 18/50 (36%), Positives = 27/50 (54%), Gaps = 4/50 (8%)
 Frame = -1

Query: 30   LDLDNSGSLSVEEFMSLPELQQNPLVQRVIDIF----DTDGNGEVDFKEF 75
            LD  N G + VE+   L +   + L +  I+      DTDG+G VD++EF
Sbjct: 1917 LDKGNKGVIPVEDLRWLLKSLGDDLTEDEIEDMILETDTDGSGTVDYEEF 1768
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|93277108|ref|NP_061347.2| aldo-keto reductase family
1, member E1 [Mus musculus]
         (301 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

17411                                                                 260   4e-70
00500                                                                 174   5e-44
09575                                                                 158   3e-39
02477                                                                 134   5e-32
20851                                                                 104   3e-30
31792                                                                  97   1e-20
08973                                                                  79   2e-15
26455                                                                  50   8e-13
24743                                                                  55   3e-08
05102                                                                  37   0.014
19023                                                                  32   0.26 
13564                                                                  32   0.40 
22438                                                                  29   2.0  
>17411
          Length = 1104

 Score =  260 bits (665), Expect = 4e-70,   Method: Compositional matrix adjust.
 Identities = 135/303 (44%), Positives = 193/303 (63%), Gaps = 5/303 (1%)
 Frame = -3

Query: 4    IPTVGLGTWKASPGEVTDAVKLAINLGYRHFDCAYLYHNESEVGMGISEKIKEGVVKRED 63
            IP +GLGT+ +   E   A+K AI++GYRH D AY   NE EVG  I +KI EGVV+RED
Sbjct: 1036 IPILGLGTYTSKDNEGEIAIKXAIDVGYRHIDTAYFXQNEFEVGKAIRDKIAEGVVQRED 857

Query: 64   LFVVSKLWCTCHKKSLVKTACTNTLEALNLDYLDLYLIHWPMGFK--PGEKDIPLDRNGK 121
            +F+V+KLW   H   LV++AC   L  L +DY+DLYLIH P+G+K    E  +P D N +
Sbjct: 856  IFLVTKLWNIHHDPKLVESACRKQLALLCMDYIDLYLIHQPVGYKFIDEETLVPKDANNE 677

Query: 122  VIPSHTSFLDTWEAMEDLVFEGLVKNLGVSNFNHEQLERLLDKPGLRVRPITNQIECHPY 181
            +  S   +LDT++AME LV  GLV+++GVSNFN EQL R+++     ++P+TNQ+EC P 
Sbjct: 676  LQLSDVDYLDTYKAMEQLVKIGLVRSIGVSNFNSEQLLRVIN--NCEIKPVTNQVECSPA 503

Query: 182  LNQKKLIDFCHKRNVSVTAYRPLGG---SGGGFHLMDDTVIRKIAKKHGKSPAQILIRFQ 238
            +NQKKLI FC +  V++TAYRPLG           +    ++ IA+K+ KS  Q+++R+ 
Sbjct: 502  INQKKLIAFCKQHGVTLTAYRPLGKPQPDQNKPEYLYSPEVKAIAQKYKKSAPQVILRYL 323

Query: 239  IQRNLIVIPKSVTPSRIRENIQVFDFELTEKDMEELLSLDKNLRLATFPTTENHQDYPFH 298
            ++   + IPKS  P RI EN  +FDFELT ++   L   +   R     + ++H+ YPF 
Sbjct: 322  VELGTLPIPKSSNPGRIAENFNIFDFELTAEEKCVLDGYNTGERNVPMTSLKHHKYYPFA 143

Query: 299  IEY 301
            IE+
Sbjct: 142  IEF 134
>00500
          Length = 730

 Score =  174 bits (440), Expect = 5e-44,   Method: Compositional matrix adjust.
 Identities = 83/209 (39%), Positives = 130/209 (62%), Gaps = 4/209 (1%)
 Frame = +2

Query: 4   IPTVGLGTW---KASPGEVTDAVKLAINLGYRHFDCAYLYHNESEVGMGISEKIKEGVVK 60
           +P V  GTW   ++  GEV   VK A+  GY H D A++Y NE EVG  +++ I+EG + 
Sbjct: 14  MPVVAYGTWTVWQSKAGEVYRGVKTALEAGYGHVDTAWVYDNEHEVGQAVADVIQEGSLT 193

Query: 61  REDLFVVSKLWCTCHKKSLVKTACTNTLEALNLDYLDLYLIHWPMGFKPGEKD-IPLDRN 119
           R D+F+ +K+W T H +  VK     +L  L L Y+DL L+H+P  FK  + D  P   +
Sbjct: 194 RGDIFITTKIWDTYHSRERVKLNVEKSLAKLKLSYVDLVLMHYPTSFKDTDDDNFPKGPD 373

Query: 120 GKVIPSHTSFLDTWEAMEDLVFEGLVKNLGVSNFNHEQLERLLDKPGLRVRPITNQIECH 179
           GK+I S+   LDTW+ +ED V  GLV+N+GVSNFN +Q++R++D     ++P   Q+E +
Sbjct: 374 GKIIYSNHDLLDTWKGLEDCVRAGLVRNIGVSNFNSQQIKRVVD--AASIKPCNLQVEIN 547

Query: 180 PYLNQKKLIDFCHKRNVSVTAYRPLGGSG 208
           P ++ ++L+ F   + ++V++Y PLG  G
Sbjct: 548 PTMSNERLVKFAESQGLTVSSYAPLGAPG 634
>09575
          Length = 734

 Score =  158 bits (399), Expect = 3e-39,   Method: Compositional matrix adjust.
 Identities = 77/194 (39%), Positives = 126/194 (64%), Gaps = 7/194 (3%)
 Frame = +1

Query: 93  LDYLDLYLIHWPMGFKPGEKD-IPLDRNGKVIPSHTSFLDTWEAMEDLVFEGLVKNLGVS 151
           L Y+DL L+H+P  FK  + D  P   +GK+I S+   LDTW+ +ED V  GLV+N+GVS
Sbjct: 4   LSYVDLVLMHYPTSFKDTDDDNFPKGPDGKIIYSNHDLLDTWKGLEDCVXAGLVRNIGVS 183

Query: 152 NFNHEQLERLLDKPGLRVRPITNQIECHPYLNQKKLIDFCHKRNVSVTAYRPLGGSGGGF 211
           NFN +Q++R++D     ++P   Q+E +P ++ ++L+ F   + ++V++Y PLG  G  +
Sbjct: 184 NFNSQQIKRVVD--AASIKPCNLQVEINPTMSNERLVKFAESQGLTVSSYAPLGAPGRPW 357

Query: 212 H------LMDDTVIRKIAKKHGKSPAQILIRFQIQRNLIVIPKSVTPSRIRENIQVFDFE 265
                   ++D V+  IA K GK+PAQ+++R+ +QR + V  KS+   RIR+NI VF+FE
Sbjct: 358 KESTDPCAIEDPVVTGIASKKGKTPAQVILRWLLQRGVCVCVKSLNVDRIRQNIDVFNFE 537

Query: 266 LTEKDMEELLSLDK 279
           L+E +M ++  L+K
Sbjct: 538 LSEDEMTQMSGLNK 579
>02477
          Length = 1091

 Score =  134 bits (337), Expect = 5e-32,   Method: Compositional matrix adjust.
 Identities = 75/210 (35%), Positives = 110/210 (52%)
 Frame = +1

Query: 80  VKTACTNTLEALNLDYLDLYLIHWPMGFKPGEKDIPLDRNGKVIPSHTSFLDTWEAMEDL 139
            + AC  +L  L   YLDL+LIHWP      +K  P D   K      + L +W  ME L
Sbjct: 13  CRAACLQSLSRLQCSYLDLFLIHWP----GTQKLQPHDARHKA-----NRLASWADMEQL 165

Query: 140 VFEGLVKNLGVSNFNHEQLERLLDKPGLRVRPITNQIECHPYLNQKKLIDFCHKRNVSVT 199
             EG +K +GVSNF    LE +L      V+P   QIE HP+L Q  L+ +C +  +   
Sbjct: 166 HKEGKLKAIGVSNFLQHHLEEIL--AVCSVKPAVLQIEFHPHLVQSNLLSWCTQNTIHFQ 339

Query: 200 AYRPLGGSGGGFHLMDDTVIRKIAKKHGKSPAQILIRFQIQRNLIVIPKSVTPSRIRENI 259
           AY  LG +     L+ D  ++ IA ++ ++PAQIL+ + +Q+ + V+PKS     I EN 
Sbjct: 340 AYSSLGTTSDNNKLLTDQTVQSIASRYNRTPAQILLHWAVQQGVGVLPKSTNQKHIEENG 519

Query: 260 QVFDFELTEKDMEELLSLDKNLRLATFPTT 289
           ++FDF L + DM+ L SL  +      P+ 
Sbjct: 520 EIFDFTLEDSDMQALSSLHSDTHYCWDPSA 609
>20851
          Length = 408

 Score =  104 bits (260), Expect(2) = 3e-30,   Method: Compositional matrix adjust.
 Identities = 54/109 (49%), Positives = 69/109 (63%), Gaps = 5/109 (4%)
 Frame = +2

Query: 31  YRHFDCAYLYHNESEVGMGISEKIKEGVVKREDLFVVSKLWCTCHKKSLVKTACTNTLEA 90
           YRHFD A++Y  E  VG GI+ KI++G VKREDLF+VSKLW TCH +  V+ +   TL  
Sbjct: 2   YRHFDTAWVYETEKAVGEGIARKIQDGTVKREDLFIVSKLWNTCHSR--VEASLRETLNN 175

Query: 91  LNLDYLDLYLIHWPMGFK-----PGEKDIPLDRNGKVIPSHTSFLDTWE 134
           L L YLDLYLIHWP+ FK     PG + + L R   +I    +   TW+
Sbjct: 176 LQLGYLDLYLIHWPIAFKKVENPPGPR-VDLSRASLLITILLTRTRTWK 319

 Score = 45.1 bits (105), Expect(2) = 3e-30,   Method: Compositional matrix adjust.
 Identities = 22/37 (59%), Positives = 27/37 (72%)
 Frame = +1

Query: 129 FLDTWEAMEDLVFEGLVKNLGVSNFNHEQLERLLDKP 165
           F+DT++ ME LV + LV +LGVSNFN  QL RLL  P
Sbjct: 292 FVDTYKDMEKLVDQRLVNSLGVSNFNTHQLTRLLSVP 402
>31792
          Length = 377

 Score = 96.7 bits (239), Expect = 1e-20,   Method: Compositional matrix adjust.
 Identities = 50/124 (40%), Positives = 77/124 (62%), Gaps = 8/124 (6%)
 Frame = -3

Query: 136 MEDLVFEGLVKNLGVSNFNHEQLERLLDKPGLRVRPITNQIECHPYLNQKKLIDFCHKRN 195
           +E LV EG +++LG+SNFN  Q++  L      V+P+ NQ+ECH YL QK+L  FC KRN
Sbjct: 366 LEKLVQEGKIRSLGISNFNSVQVD--LINFVATVKPVINQVECHAYLAQKELQAFCQKRN 193

Query: 196 VSVTAYRPLGGSGGGFH--------LMDDTVIRKIAKKHGKSPAQILIRFQIQRNLIVIP 247
           + + A+ PLG  G   H        L+++ V+  I +K+ K+PAQ+L+R   QR + ++ 
Sbjct: 192 IFLQAFAPLGSPGRPEHMVTDGDPVLLEEPVLASIGEKYKKTPAQVLLRNLFQRGMAMVA 13

Query: 248 KSVT 251
           KS +
Sbjct: 12  KSCS 1
>08973
          Length = 567

 Score = 79.3 bits (194), Expect = 2e-15,   Method: Compositional matrix adjust.
 Identities = 43/125 (34%), Positives = 63/125 (50%), Gaps = 3/125 (2%)
 Frame = -3

Query: 180 PYLNQKKLIDFCHKRNVSVTAYRPLGGSGGGFH---LMDDTVIRKIAKKHGKSPAQILIR 236
           P   Q KL     K  + + AY PL       H    + D   +++AKK+G++ AQI + 
Sbjct: 565 PAFQQHKLRAHAKKHGIVICAYCPLARPQPARHWPPFLYDERAQQLAKKYGRTAAQICLX 386

Query: 237 FQIQRNLIVIPKSVTPSRIRENIQVFDFELTEKDMEELLSLDKNLRLATFPTTENHQDYP 296
           + IQ  ++ +PKS    RI EN   FDFEL  +DM  +     N+R   F    +HQ YP
Sbjct: 385 YLIQSGVVPLPKSSNKKRIAENFNCFDFELMPEDMLAMEKYHTNVRTVPFSGMSSHQYYP 206

Query: 297 FHIEY 301
           F+ E+
Sbjct: 205 FNDEF 191
>26455
          Length = 466

 Score = 50.1 bits (118), Expect(2) = 8e-13,   Method: Compositional matrix adjust.
 Identities = 23/40 (57%), Positives = 29/40 (72%)
 Frame = -2

Query: 36  CAYLYHNESEVGMGISEKIKEGVVKREDLFVVSKLWCTCH 75
           C + Y NE EVG  I +KI EGVV+RED+F+V+KLW   H
Sbjct: 135 CVF-YQNEFEVGKAIRDKIAEGVVQREDIFLVTKLWNIHH 19

 Score = 40.4 bits (93), Expect(2) = 8e-13,   Method: Compositional matrix adjust.
 Identities = 18/36 (50%), Positives = 24/36 (66%)
 Frame = -3

Query: 4   IPTVGLGTWKASPGEVTDAVKLAINLGYRHFDCAYL 39
           IP +GLGT+ +   E   A+K AI++GYRH D AY 
Sbjct: 233 IPILGLGTYTSKDNEGEIAIKHAIDVGYRHIDTAYF 126
>24743
          Length = 342

 Score = 55.5 bits (132), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 34/89 (38%), Positives = 44/89 (49%)
 Frame = +3

Query: 80  VKTACTNTLEALNLDYLDLYLIHWPMGFKPGEKDIPLDRNGKVIPSHTSFLDTWEAMEDL 139
            + AC  +L  L   YLDL+LIHWP      +K  P D   K      + L +W  ME L
Sbjct: 36  CRAACLQSLSRLQCSYLDLFLIHWP----GTQKLQPHDARHK-----ANRLXSWADMEQL 188

Query: 140 VFEGLVKNLGVSNFNHEQLERLLDKPGLR 168
             EG +K +GVSNF    LE +L    +R
Sbjct: 189 HKEGKLKAIGVSNFLQHHLEEILAVCSVR 275
>05102
          Length = 1532

 Score = 36.6 bits (83), Expect = 0.014,   Method: Compositional matrix adjust.
 Identities = 27/120 (22%), Positives = 48/120 (40%), Gaps = 2/120 (1%)
 Frame = -3

Query: 87   TLEALNLDYLDLYLIHWPMGFKPGEKDIPLDRNGKVIPSHTSFLDTWEAMEDLVFEGLVK 146
             L  +  DY+D+  IH+P   K                      +T   ++  +  G ++
Sbjct: 1521 ALRKMETDYIDILQIHFPSFVK-------------------DMKETLAELDSQIARGRLR 1399

Query: 147  NLGVSNFNHEQLERLLDKPGLRVRPITNQIECHPYLN--QKKLIDFCHKRNVSVTAYRPL 204
            + G SNF  + L+  LD      +P+ NQ+  +      +  +   C   N+S+ AY PL
Sbjct: 1398 HYGFSNFGPKNLKAFLDAG---AKPVVNQMGYNLLWRSVEYDVQSICAANNISILAYSPL 1228
>19023
          Length = 460

 Score = 32.3 bits (72), Expect = 0.26,   Method: Compositional matrix adjust.
 Identities = 13/35 (37%), Positives = 21/35 (60%)
 Frame = +3

Query: 111 EKDIPLDRNGKVIPSHTSFLDTWEAMEDLVFEGLV 145
            K +    NG+ IP HTSFL    ++E +++ G+V
Sbjct: 3   HKLVVFANNGRNIPVHTSFLTLTASLETVIYFGMV 107
>13564
          Length = 842

 Score = 31.6 bits (70), Expect = 0.40,   Method: Compositional matrix adjust.
 Identities = 15/44 (34%), Positives = 29/44 (65%)
 Frame = +1

Query: 133 WEAMEDLVFEGLVKNLGVSNFNHEQLERLLDKPGLRVRPITNQI 176
           W+A+EDLV +  V ++GV++ +  +L++L      +V+P  NQ+
Sbjct: 127 WKALEDLVDQERVLSIGVADLDKHKLDQLYQ--WAKVKPRINQV 252
>22438
          Length = 756

 Score = 29.3 bits (64), Expect = 2.0,   Method: Compositional matrix adjust.
 Identities = 11/28 (39%), Positives = 17/28 (60%)
 Frame = -2

Query: 122 VIPSHTSFLDTWEAMEDLVFEGLVKNLG 149
           V+P+H   L+ W A + L F G V++L 
Sbjct: 95  VVPAHFRILE*WHAWKALCFTGFVRSLA 12
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|33563282|ref|NP_036095.1| proteasome (prosome,
macropain) subunit, alpha type 1 [Mus musculus]
         (263 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

19133                                                                 260   5e-70
02448                                                                 154   4e-38
24591                                                                 153   7e-38
14551                                                                 127   6e-30
00789                                                                 117   3e-27
20771                                                                 116   9e-27
17033                                                                 109   1e-24
04255                                                                  77   1e-20
09721                                                                  66   2e-11
28971                                                                  52   3e-07
34924                                                                  36   0.013
37174                                                                  32   0.31 
18900                                                                  29   1.7  
02262                                                                  28   2.9  
06271                                                                  28   3.2  
12779                                                                  27   7.2  
>19133
          Length = 692

 Score =  260 bits (664), Expect = 5e-70,   Method: Compositional matrix adjust.
 Identities = 118/163 (72%), Positives = 144/163 (88%)
 Frame = +1

Query: 77  LTADARLLCNFMRQECLDSRFVFDRPLPVSRLVSLIGSKTQIPTQRYGRRPYGVGLLIAG 136
           LTADARLLCNFM+ ECLDSR+ + +PLPVSRLVS IG+K QIPT RYGRRP+GVGLLIAG
Sbjct: 1   LTADARLLCNFMQTECLDSRWAYQQPLPVSRLVSAIGNKLQIPTHRYGRRPFGVGLLIAG 180

Query: 137 YDDMGPHIFQTCPSANYFDCRAMSIGARSQSARTYLERHMSEFMECNLDELVKHGLRALR 196
           YD  GPHI+QTCPSANY+DC+AM+IGARSQSARTYLERH+ +F +C+LDELVKHGLRALR
Sbjct: 181 YDWSGPHIYQTCPSANYYDCKAMAIGARSQSARTYLERHLDQFPQCSLDELVKHGLRALR 360

Query: 197 ETLPAEQDLTTKNVSIGIVGKDLEFTIYDDDDVSPFLDGLEER 239
           +TLP+E  L+TKN S+GIV KD++F IYDD++V+ +L  +E +
Sbjct: 361 DTLPSEVTLSTKNCSLGIVDKDMKFKIYDDENVASYLALIEGK 489
>02448
          Length = 1302

 Score =  154 bits (389), Expect = 4e-38,   Method: Compositional matrix adjust.
 Identities = 80/233 (34%), Positives = 135/233 (57%), Gaps = 3/233 (1%)
 Frame = +2

Query: 4   NQYDNDVTVWSPQGRIHQIEYAMEAVKQGSATVGLKSKTHAVLVALKRAQSELAAHQ--K 61
           ++YD  +TV+SP G + Q+EYA EAVK+GS  VG++     VL   K+A ++L   +  +
Sbjct: 257 DRYDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGNNLVVLGVEKKAVAKLQEERTVR 436

Query: 62  KILHVDNHIGISIAGLTADARLLCNFMRQECLDSRFVFDRPLPVSRLVSLIGSKTQIPTQ 121
           KI  +D H+ ++ AGLTADAR+L N  R EC   +   + P+ V  +   I    Q  TQ
Sbjct: 437 KIALLDEHVALAFAGLTADARILINRARIECQSHKLTVEDPVTVEYITRHIAQLKQKYTQ 616

Query: 122 RYGRRPYGVGLLIAGYD-DMGPHIFQTCPSANYFDCRAMSIGARSQSARTYLERHMSEFM 180
             GRRP+G+  LI G+D D  PH++QT PS  Y + +A +IG  +++ R +LE+H ++ +
Sbjct: 617 SNGRRPFGLSSLIIGFDYDGSPHLYQTDPSGTYHEWKANTIGRNAKTVREFLEKHYTDEV 796

Query: 181 ECNLDELVKHGLRALRETLPAEQDLTTKNVSIGIVGKDLEFTIYDDDDVSPFL 233
             +  E +K  L+AL E + +      KN+ + ++ +     + + D++  ++
Sbjct: 797 AASDKETIKLALKALLEVVQS----GAKNMEVAVMRRGQALQMLESDEIEKYI 943
>24591
          Length = 1801

 Score =  153 bits (386), Expect = 7e-38,   Method: Compositional matrix adjust.
 Identities = 80/233 (34%), Positives = 135/233 (57%), Gaps = 3/233 (1%)
 Frame = +1

Query: 4   NQYDNDVTVWSPQGRIHQIEYAMEAVKQGSATVGLKSKTHAVLVALKRAQSELAAHQ--K 61
           ++YD  +TV+SP G + Q+EYA EAVK+GS  VG++     VL   K+A ++L   +  +
Sbjct: 34  DRYDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGDNLVVLGVEKKAVAKLQEERTVR 213

Query: 62  KILHVDNHIGISIAGLTADARLLCNFMRQECLDSRFVFDRPLPVSRLVSLIGSKTQIPTQ 121
           KI  +D H+ ++ AGLTADAR+L N  R EC   +   + P+ V  +   I    Q  TQ
Sbjct: 214 KIALLDEHVALAFAGLTADARILINRARIECQSHKLTVEDPVTVEYITRHIAQLKQKYTQ 393

Query: 122 RYGRRPYGVGLLIAGYD-DMGPHIFQTCPSANYFDCRAMSIGARSQSARTYLERHMSEFM 180
             GRRP+G+  LI G+D D  PH++QT PS  Y + +A +IG  +++ R +LE+H ++ +
Sbjct: 394 SNGRRPFGLSSLIIGFDYDGTPHLYQTDPSGTYHEWKANTIGRNAKTVREFLEKHYTDEV 573

Query: 181 ECNLDELVKHGLRALRETLPAEQDLTTKNVSIGIVGKDLEFTIYDDDDVSPFL 233
             +  E +K  L+AL E + +      KN+ + ++ +     + + D++  ++
Sbjct: 574 AASDKETIKLALKALLEVVQS----GAKNMEVAVMRRGQALQMLESDEIEKYI 720
>14551
          Length = 1344

 Score =  127 bits (318), Expect = 6e-30,   Method: Compositional matrix adjust.
 Identities = 73/215 (33%), Positives = 125/215 (58%), Gaps = 5/215 (2%)
 Frame = +3

Query: 5   QYDNDVTVWSPQGRIHQIEYAMEAVKQGSATVGLKSKTHAVLVALKRAQSELAAHQ---K 61
           +Y   +T +SP G++ QIEYA+ AV  G+ +VG+K+ T+ V++A ++ Q  +   +    
Sbjct: 150 RYSFSLTTFSPSGKLVQIEYALAAVGAGAPSVGIKA-TNGVVLATEKKQKSVXYDEHSIN 326

Query: 62  KILHVDNHIGISIAGLTADARLLCNFMRQECLDSRFVFDRPLPVSRLVSLIGSKTQIPTQ 121
           K+  +  +IGI  +G+  D R+LC   R+     + V++  +P ++LV  + +  Q  TQ
Sbjct: 327 KVETITKNIGIVYSGMGPDYRVLCRRARKLAEQYKRVYNEQIPTAQLVQRVAAVMQEFTQ 506

Query: 122 RYGRRPYGVGLLIAGY--DDMGPHIFQTCPSANYFDCRAMSIGARSQSARTYLERHMSEF 179
             G RP+GV LL+AG+  DD  P ++Q  PS  YF  +A ++G    + +T+LE+  SE 
Sbjct: 507 SGGVRPFGVSLLMAGWDEDDKKPFLYQCDPSGAYFAWKATAMGKNHINGKTFLEKRYSET 686

Query: 180 MECNLDELVKHGLRALRETLPAEQDLTTKNVSIGI 214
           +E  L++ V   + AL+E+   E  +T  N+ IGI
Sbjct: 687 LE--LEDAVHTAILALKESF--EGQMTEDNIEIGI 779
>00789
          Length = 1584

 Score =  117 bits (294), Expect = 3e-27,   Method: Compositional matrix adjust.
 Identities = 66/199 (33%), Positives = 115/199 (57%), Gaps = 4/199 (2%)
 Frame = +1

Query: 5   QYDNDVTVWSPQGRIHQIEYAMEAVKQGSATVGLKSKTHAVLVALKRAQSEL---AAHQK 61
           +YD+  T++SP+GR++Q+EYAMEA+      +G+ +K   VL A +R  ++L    ++ +
Sbjct: 31  RYDSRTTIFSPEGRLYQVEYAMEAIGHAGTCLGILAKDGIVLAAERRNTNKLLDEVSYSE 210

Query: 62  KILHVDNHIGISIAGLTADARLLCNFMRQECLDSRFVFDRPLPVSRLVSLIGSKTQIPTQ 121
           KI  + + +  S+AG+T+DA +L N +R         +  P+P  ++V+ +    Q  TQ
Sbjct: 211 KIYRLSDDMACSVAGITSDANVLTNELRLIAQRYLLQYQEPIPCEQVVATLCDIKQAYTQ 390

Query: 122 RYGRRPYGVGLLIAGYDD-MGPHIFQTCPSANYFDCRAMSIGARSQSARTYLERHMSEFM 180
             G+RP+GV +L  G+D   G  ++Q+ PS NY   +A  IG  S +A + L++   E  
Sbjct: 391 FGGKRPFGVSILYMGWDKHYGFQLYQSDPSGNYGGWKATCIGNNSANAVSLLKQEYKED- 567

Query: 181 ECNLDELVKHGLRALRETL 199
           E +LDE +   ++ L +TL
Sbjct: 568 ESSLDEALALSIKVLGKTL 624
>20771
          Length = 674

 Score =  116 bits (291), Expect = 9e-27,   Method: Compositional matrix adjust.
 Identities = 63/182 (34%), Positives = 98/182 (53%), Gaps = 7/182 (3%)
 Frame = +2

Query: 1   MFRNQYDNDVTVWSPQGRIHQIEYAMEAVKQGSATVGLKSKTHAVLVALKRAQSEL--AA 58
           + R++YD  V  +SP+GR+ Q+EYA+EA+K GS  +G+++    VL   KR  S L    
Sbjct: 86  LTRSEYDRGVNTFSPEGRLFQVEYAIEAIKLGSTAIGIQTNEGVVLAVEKRVTSSLIEPT 265

Query: 59  HQKKILHVDNHIGISIAGLTADARLLCNFMRQECLDSRFVFDRPLPVSRLVSLIGSKTQI 118
             +KI+ VD HIG +++GL AD+R L +  R E  +  F ++  + V  +   + +    
Sbjct: 266 SIEKIMEVDKHIGCAMSGLIADSRTLIDRARVEAQNHWFTYNENMSVESVTQAVSNLALA 445

Query: 119 -----PTQRYGRRPYGVGLLIAGYDDMGPHIFQTCPSANYFDCRAMSIGARSQSARTYLE 173
                P      RP+GV LLIAG D  GP +F   PS  +    A +IG+ S+ A+  L+
Sbjct: 446 FGDDDPDPGAMSRPFGVALLIAGVDSNGPRLFHMDPSGTFIQYDAKAIGSGSEGAQQALQ 625

Query: 174 RH 175
             
Sbjct: 626 EQ 631
>17033
          Length = 2217

 Score =  109 bits (272), Expect = 1e-24,   Method: Compositional matrix adjust.
 Identities = 59/192 (30%), Positives = 100/192 (52%), Gaps = 2/192 (1%)
 Frame = -3

Query: 6    YDNDVTVWSPQGRIHQIEYAMEAVKQGSATVGLKSKTHAVLVALKRAQSEL--AAHQKKI 63
            YD   + +SP GR+ Q+EYA +AV+     +G++ K   V+   K   S+L      K++
Sbjct: 2149 YDLSASHFSPDGRVFQVEYAQKAVENSGTAIGIRGKDGVVMGVEKLVTSKLYEQGANKRL 1970

Query: 64   LHVDNHIGISIAGLTADARLLCNFMRQECLDSRFVFDRPLPVSRLVSLIGSKTQIPTQRY 123
             ++D HIG ++AGL ADAR L    ++E  + RF +  P+P+  L   +       T   
Sbjct: 1969 FNIDRHIGGAVAGLLADARQLMERAKEESSNYRFNYGSPVPLKYLTDRVAGYVHAYTLHS 1790

Query: 124  GRRPYGVGLLIAGYDDMGPHIFQTCPSANYFDCRAMSIGARSQSARTYLERHMSEFMECN 183
              RP+G  +++A YD +GP +F   PS   +     +IG   Q+A+T +E+   +  +  
Sbjct: 1789 AVRPFGTSMIVASYDAVGPQMFLVEPSGVSWGYYGCAIGKAKQTAKTEIEK--LKMKDLT 1616

Query: 184  LDELVKHGLRAL 195
            + +LVK   R +
Sbjct: 1615 MQDLVKEVARII 1580
>04255
          Length = 1758

 Score = 77.0 bits (188), Expect(2) = 1e-20,   Method: Compositional matrix adjust.
 Identities = 48/172 (27%), Positives = 81/172 (47%), Gaps = 2/172 (1%)
 Frame = -2

Query: 70   IGISIAGLTADARLLCNFMRQECLDSRFVFDRPLPVSRLVSLIGSKTQIPTQRYGRRPYG 129
            IG  + G+ AD++      R E    ++ +   +PV  L   I +  Q+ TQ    RP G
Sbjct: 1406 IGCVMTGMIADSQSQVQRARYEAAKWKYTYGYDIPVDMLCKRIANINQVYTQSAEMRPLG 1227

Query: 130  VGLLIAGYDD-MGPHIFQTCPSANYFDCRAMSIGARSQSARTYLERHMSEFMECNLDELV 188
              +++ GYDD  GP +++T P+  Y   +A S G++   A  +LE+ + +  +   +E  
Sbjct: 1226 CCMILIGYDDEKGPEVYKTDPAGYYCGFKATSAGSKQLEANGFLEKKIKKKQDFTYNEAA 1047

Query: 189  KHGLRALRETLPAEQDLTTKNVSIGIVGKD-LEFTIYDDDDVSPFLDGLEER 239
            +  +  L   L A  D     V +GIV KD   F I  + D+   L  + E+
Sbjct: 1046 EIAITCLSTVLSA--DFKASEVEVGIVTKDNPNFRILTEADIDVHLTAIAEK 897

 Score = 39.7 bits (91), Expect(2) = 1e-20,   Method: Compositional matrix adjust.
 Identities = 18/39 (46%), Positives = 28/39 (71%), Gaps = 1/39 (2%)
 Frame = -3

Query: 14   SPQGRIHQIEYAMEAVKQGSAT-VGLKSKTHAVLVALKR 51
            SP+GR++Q+EYA +A+ QG  T V ++ K  AV+V  K+
Sbjct: 1582 SPEGRLYQVEYAFKAINQGGLTSVAVRGKDSAVIVTQKK 1466
>09721
          Length = 919

 Score = 65.9 bits (159), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 29/39 (74%), Positives = 34/39 (87%)
 Frame = -1

Query: 77  LTADARLLCNFMRQECLDSRFVFDRPLPVSRLVSLIGSK 115
           LTADARLLCNFM+ ECLDSR+ + +PLPVSRLVS IG+ 
Sbjct: 919 LTADARLLCNFMQTECLDSRWAYQQPLPVSRLVSAIGNS 803
>28971
          Length = 437

 Score = 51.6 bits (122), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 21/57 (36%), Positives = 37/57 (64%)
 Frame = +1

Query: 120 TQRYGRRPYGVGLLIAGYDDMGPHIFQTCPSANYFDCRAMSIGARSQSARTYLERHM 176
           TQ  G RP+GV LLI G+D+  P+++Q+ PS  YF  +A ++G  + + + +L + +
Sbjct: 13  TQSGGVRPFGVSLLICGWDNERPYLYQSDPSGAYFAWKATAMGKNAVNGKNFLGKAL 183
>34924
          Length = 413

 Score = 36.2 bits (82), Expect = 0.013,   Method: Compositional matrix adjust.
 Identities = 14/32 (43%), Positives = 23/32 (71%)
 Frame = +3

Query: 207 TKNVSIGIVGKDLEFTIYDDDDVSPFLDGLEE 238
            +N S+GIV +D++F IYDDD V+ ++  L +
Sbjct: 246 VQNCSLGIVSQDMKFAIYDDDKVASYVSLLSQ 341
>37174
          Length = 146

 Score = 31.6 bits (70), Expect = 0.31,   Method: Composition-based stats.
 Identities = 14/32 (43%), Positives = 20/32 (62%)
 Frame = +1

Query: 15 PQGRIHQIEYAMEAVKQGSATVGLKSKTHAVL 46
          P  ++ QIEYA+ AV  G+  VG+K+    VL
Sbjct: 43 PTAQLVQIEYALAAVGAGAPVVGIKATNGVVL 138
>18900
          Length = 883

 Score = 29.3 bits (64), Expect = 1.7,   Method: Compositional matrix adjust.
 Identities = 17/57 (29%), Positives = 30/57 (52%)
 Frame = -1

Query: 144 IFQTCPSANYFDCRAMSIGARSQSARTYLERHMSEFMECNLDELVKHGLRALRETLP 200
           +  T P  +  DCR  SIGA  Q++    + H+  F+EC+   ++ H +  L ++ P
Sbjct: 586 VILTQPRESGTDCRTDSIGAGLQASS--FQTHV--FLECHFTIVLGHSMSRLAQSHP 428
>02262
          Length = 1605

 Score = 28.5 bits (62), Expect = 2.9,   Method: Compositional matrix adjust.
 Identities = 12/33 (36%), Positives = 18/33 (54%)
 Frame = -1

Query: 148 CPSANYFDCRAMSIGARSQSARTYLERHMSEFM 180
           CP    FD R+MSI  +  S   +L+ H  E++
Sbjct: 816 CPPFTSFDIRSMSITVKFFSGICFLKGHACEYL 718
>06271
          Length = 2023

 Score = 28.5 bits (62), Expect = 3.2,   Method: Compositional matrix adjust.
 Identities = 27/91 (29%), Positives = 41/91 (45%), Gaps = 14/91 (15%)
 Frame = +2

Query: 143 HIFQTCPSANYFDCRAMSIGAR--SQSARTYL------------ERHMSEFMECNLDELV 188
           HI+  C S N F CR  S+ A   SQ+ + Y+            +RH S F+      L 
Sbjct: 308 HIYVLCVSCN*FKCRGESLLAYAGSQAPKNYVREVSGTGPLRLAQRHFSLFL-----NL* 472

Query: 189 KHGLRALRETLPAEQDLTTKNVSIGIVGKDL 219
           K   ++L      +QDL  K+ S  ++G D+
Sbjct: 473 KIHTQSLTPVTCLQQDL--KSYSGELLGADI 559
>12779
          Length = 735

 Score = 27.3 bits (59), Expect = 7.2,   Method: Compositional matrix adjust.
 Identities = 12/28 (42%), Positives = 18/28 (64%)
 Frame = +1

Query: 210 VSIGIVGKDLEFTIYDDDDVSPFLDGLE 237
           + IGI+GK L   IY +D +S  +D L+
Sbjct: 226 IGIGIIGKSLRCQIYINDTMSRLIDILQ 309
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|34878892|ref|NP_035027.1| neurofibromin [Mus
musculus]
         (2841 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

18860                                                                 234   6e-70
19358                                                                 248   3e-65
21062                                                                  72   4e-12
28193                                                                  55   5e-07
11228                                                                  41   0.008
01438                                                                  35   0.50 
18151                                                                  33   1.1  
05820                                                                  32   4.6  
28771                                                                  31   8.4  
>18860
          Length = 560

 Score =  234 bits (596), Expect(2) = 6e-70,   Method: Compositional matrix adjust.
 Identities = 114/156 (73%), Positives = 130/156 (83%)
 Frame = -1

Query: 1169 LGYHKDLQTRATFMEVLTKILQQGTEFDTLAETVLADRFERLVELVTMMGDQGELPIAMA 1228
            +GYHKD QTRA FMEVLTKILQQGTEF+TLAET LADRFERLVELVTM+GD+GELPIAMA
Sbjct: 470  IGYHKDPQTRAAFMEVLTKILQQGTEFETLAETALADRFERLVELVTMIGDKGELPIAMA 291

Query: 1229 LANVVPCSQWDELARVLVTLFDSRHLLYQLLWNMFSKEVELADSMQTLFRGNSLASKIMT 1288
            LA VV  +Q DELARV V+LFD++ LLYQLLWNMFSKEVE+AD MQTLFRGNSLASKIM 
Sbjct: 290  LAQVVSNTQMDELARVFVSLFDAKRLLYQLLWNMFSKEVEVADCMQTLFRGNSLASKIMA 111

Query: 1289 FCFKVYGATYLQKLLDPLLRVIITSSDWQHVSFEVD 1324
            +CF+ YG  YL  LL PL++ +        VS+E+D
Sbjct: 110  YCFRFYGQWYLCDLLSPLIQEMFHLEKETQVSYEID 3

 Score = 52.0 bits (123), Expect(2) = 6e-70,   Method: Compositional matrix adjust.
 Identities = 24/32 (75%), Positives = 28/32 (87%)
 Frame = -2

Query: 1139 RLASLRHCTVLAMSNLLNANVDSGLMHSIGLG 1170
             L++LR+CTV AMSNLLNAN+DSGLMHSI L 
Sbjct: 559  NLSALRNCTVQAMSNLLNANIDSGLMHSIALA 464
>19358
          Length = 455

 Score =  248 bits (633), Expect = 3e-65,   Method: Compositional matrix adjust.
 Identities = 106/151 (70%), Positives = 133/151 (88%)
 Frame = -1

Query: 1562 SSLNLTSSKFEEFMTRHQVHEKEEFKALKTLSIFYQAGTSKAGNPIFYYVARRFKTGQIN 1621
            SS+++TS+KFEE M++H +HEK+EFK+LK L IFYQAGTSKAGNP+FYY+ARR+K G+IN
Sbjct: 455  SSMDMTSTKFEEIMSKHNMHEKDEFKSLKNLHIFYQAGTSKAGNPVFYYIARRYKVGEIN 276

Query: 1622 GDLLIYHVLLTLKPYYAKPYEIVVDLTHTGPSNRFKTDFLSKWFVVFPGFAYDNVSAVYI 1681
            GDLLIYHVLLTLKP+Y KP+E+V+D THT   NRF+TDFLSKWFVV P   Y N++A YI
Sbjct: 275  GDLLIYHVLLTLKPFYHKPFELVIDFTHTCSENRFRTDFLSKWFVVMPEIVYQNITAAYI 96

Query: 1682 YNCNSWVREYTKYHERLLTGLKGSKRLIFID 1712
            YNCNSWVREYTKYH+R+L+ LK +++L+FID
Sbjct: 95   YNCNSWVREYTKYHDRILSPLKNNRKLVFID 3
>21062
          Length = 598

 Score = 71.6 bits (174), Expect = 4e-12,   Method: Composition-based stats.
 Identities = 58/143 (40%), Positives = 74/143 (51%), Gaps = 2/143 (1%)
 Frame = +3

Query: 2699 QYQTSYLQSFGFNGLWRFAGPFSKQTQIPDYAELIVKFLDA--LIDTYLPGIDXXXXXXX 2756
            Q Q SYLQS GF GLWRFAG F+K T   D AEL V  L+   ++++ LPG D       
Sbjct: 9    QQQLSYLQSIGFGGLWRFAGTFTKSTGSSDIAELFVNCLEKAMMVESCLPGDDL------ 170

Query: 2757 XXXXXXXYPPALQSQLSITANLNLSNSMTSLATSQHSPGLDKENVELSPTAGHCNSGRTR 2816
                           L I++ LNLS+SM+SL+        DK+    S   G  N GR R
Sbjct: 171  -------------DSLVISSTLNLSSSMSSLSMGSMHSPTDKDT---SDKTGASNGGRMR 302

Query: 2817 HGSASQVQKQRSAGSFKRNSIKK 2839
            H SA+Q+  +R  GSFK+   KK
Sbjct: 303  HSSANQINAKR-GGSFKQKEKKK 368
>28193
          Length = 457

 Score = 54.7 bits (130), Expect = 5e-07,   Method: Compositional matrix adjust.
 Identities = 38/98 (38%), Positives = 52/98 (53%)
 Frame = -3

Query: 1240 ELARVLVTLFDSRHLLYQLLWNMFSKEVELADSMQTLFRGNSLASKIMTFCFKVYGATYL 1299
            E A+ LV LF   H L  L+  +  +E+ L     TLFRGNSL SK++    K+ G  YL
Sbjct: 347  EAAQPLVRLFHHHHHLIPLIRCLADREMALTTDPNTLFRGNSLLSKMIDELMKLVGLPYL 168

Query: 1300 QKLLDPLLRVIITSSDWQHVSFEVDPTRLEPSESLEEN 1337
                   L+V I S   +    E+DP+RL+  ESL +N
Sbjct: 167  HD----TLKVFIDSVCDEPKPCEIDPSRLKEGESLTDN 66
>11228
          Length = 2155

 Score = 40.8 bits (94), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 27/115 (23%), Positives = 53/115 (46%)
 Frame = -3

Query: 1187 KILQQGTEFDTLAETVLADRFERLVELVTMMGDQGELPIAMALANVVPCSQWDELARVLV 1246
            ++L    E+ +L E ++ + +E L                + LA + P  +W  LAR L+
Sbjct: 353  QVLLPQAEYTSLKELLIEEGYENL----------------LTLAQLCPKQEWSTLARALL 222

Query: 1247 TLFDSRHLLYQLLWNMFSKEVELADSMQTLFRGNSLASKIMTFCFKVYGATYLQK 1301
             +F S      LL  +   E++    + TLFR  +LA+ +M    K+  + ++++
Sbjct: 221  RIFSSDRKEVVLLRTLNDHEIDKEVEVSTLFRATTLATTLMDQYMKMTSSDFVRQ 57
>01438
          Length = 3111

 Score = 34.7 bits (78), Expect = 0.50,   Method: Compositional matrix adjust.
 Identities = 11/34 (32%), Positives = 23/34 (67%)
 Frame = -1

Query: 1441 LKLMSKVLQSIANHVLFTKEEHMRPFNDFVKSNF 1474
            L ++S +   +A+HV+F   +H++P  D++ SN+
Sbjct: 111  LSMLSSITD*LASHVIFCPRDHLKPLQDYLHSNY 10
>18151
          Length = 1032

 Score = 33.5 bits (75), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 21/101 (20%), Positives = 41/101 (40%)
 Frame = +2

Query: 1589 LKTLSIFYQAGTSKAGNPIFYYVARRFKTGQINGDLLIYHVLLTLKPYYAKPYEIVVDLT 1648
            + +L   Y++G  + G P+  +V   F     + D  + +++  +      PY +V   T
Sbjct: 413  IASLRCLYRSGVDRHGRPVIVFVGANFSARDCDMDRALLYMVKVMDTVVDSPYVVVYFHT 592

Query: 1649 HTGPSNRFKTDFLSKWFVVFPGFAYDNVSAVYIYNCNSWVR 1689
             T  SN    +FL + +         N+     Y+ N  V+
Sbjct: 593  LTNSSNHPPMNFLKEAYSRLDNRYKKNLKKFLYYSSNMVVK 715
>05820
          Length = 1525

 Score = 31.6 bits (70), Expect = 4.6,   Method: Compositional matrix adjust.
 Identities = 22/79 (27%), Positives = 33/79 (41%), Gaps = 13/79 (16%)
 Frame = -2

Query: 723 CGVDEVSVHNFLPNYNTFMEFASVSNMMSTGR-------------AALQKRVMALLRRIE 769
           C +  +S+   + N NT +EF   S MM+  +             A L K        I 
Sbjct: 813 CSIIRLSLSQVITNKNTTVEFILFSKMMTHAKSDFSTLFSQRCSNATLNKVYXXKSSYIL 634

Query: 770 HPTAGNIEAWEDTHAKWEQ 788
           HPTA + ++  D HA  +Q
Sbjct: 633 HPTASSQKSCGDRHAMKQQ 577
>28771
          Length = 810

 Score = 30.8 bits (68), Expect = 8.4,   Method: Compositional matrix adjust.
 Identities = 16/33 (48%), Positives = 20/33 (60%)
 Frame = -1

Query: 1340 NLLQMTEKFFHAIISSSSEFPSQLRSVCHCLYQ 1372
            N+L+ T +  H +    S F SQ R VCHCLYQ
Sbjct: 483  NMLKHTIQRTHTV----SHFISQSREVCHCLYQ 397
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6753364|ref|NP_033991.1| cell division cycle 42 [Mus
musculus]
         (191 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

11728                                                                 259   6e-70
19656                                                                 194   2e-50
19006                                                                 174   3e-44
17872                                                                 153   5e-38
31291                                                                 150   3e-37
10708                                                                  85   1e-17
09700                                                                  83   6e-17
08428                                                                  72   1e-13
17511                                                                  67   3e-12
00858                                                                  67   5e-12
14456                                                                  66   9e-12
34468                                                                  62   1e-10
01972                                                                  48   2e-10
07465                                                                  61   3e-10
32770                                                                  60   7e-10
07580                                                                  57   4e-09
26083                                                                  55   2e-08
11257                                                                  54   3e-08
35581                                                                  51   4e-07
30760                                                                  50   6e-07
27191                                                                  50   8e-07
34359                                                                  48   3e-06
13901                                                                  47   4e-06
26536                                                                  47   5e-06
36757                                                                  46   8e-06
13750                                                                  45   2e-05
05468                                                                  45   2e-05
33794                                                                  43   6e-05
09204                                                                  43   9e-05
33374                                                                  42   1e-04
33380                                                                  41   3e-04
01398                                                                  40   5e-04
00552                                                                  39   0.001
36482                                                                  36   0.011
24619                                                                  32   0.18 
19046                                                                  30   0.46 
06994                                                                  29   1.4  
21806                                                                  27   4.5  
>11728
          Length = 635

 Score =  259 bits (661), Expect = 6e-70,   Method: Compositional matrix adjust.
 Identities = 118/165 (71%), Positives = 138/165 (83%)
 Frame = -1

Query: 1   MQTIKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAG 60
           MQ IKCVVVGDGAVGKTCLLISYTTN FP EY+PTVFDNY+  VM+  +P  LGL+DTAG
Sbjct: 497 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDSKPINLGLWDTAG 318

Query: 61  QEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPKTPFLLVGTQIDLR 120
           QEDYDRLRPLSYPQTDVFL+CFS++SP+SFENVK KW PE++HHCP TP +LVGT++DLR
Sbjct: 317 QEDYDRLRPLSYPQTDVFLICFSLISPASFENVKAKWYPEVSHHCPNTPIILVGTKLDLR 138

Query: 121 DDPSTIEKLAKNKQKPITPETAEKLARDLKAVKYVECSALTQKGL 165
           +D  TIEKL + K  PIT      +A+D+ A KY+ECSALTQKGL
Sbjct: 137 EDKETIEKLKEKKLAPITYPQGLAMAKDIGAGKYLECSALTQKGL 3
>19656
          Length = 428

 Score =  194 bits (492), Expect = 2e-50,   Method: Compositional matrix adjust.
 Identities = 85/108 (78%), Positives = 94/108 (87%)
 Frame = +3

Query: 1   MQTIKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAG 60
           MQ IKCVVVGDGAVGKTCLLISYTTN FP EY+PTVFDNY+  VM+ G P  LGL+DTAG
Sbjct: 105 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGRPVNLGLWDTAG 284

Query: 61  QEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPKT 108
           QEDYDRLRPLSYPQTDVFL+CFSV SP+SFEN++ KW PE+ HHCP T
Sbjct: 285 QEDYDRLRPLSYPQTDVFLLCFSVASPASFENIRAKWYPEVNHHCPGT 428
>19006
          Length = 568

 Score =  174 bits (440), Expect = 3e-44,   Method: Compositional matrix adjust.
 Identities = 78/144 (54%), Positives = 102/144 (70%)
 Frame = -2

Query: 5   KCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAGQEDY 64
           K V+VGDGA GKTCLLI ++ ++FP  YVPTVF+NY   + +  +   L L+DTAGQEDY
Sbjct: 432 KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDSKQVELALWDTAGQEDY 253

Query: 65  DRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPKTPFLLVGTQIDLRDDPS 124
           DRLRPLSYP TDV L+CFS+ SP S EN+ EKW PE+ H CP  P +LVG + DLR+D +
Sbjct: 252 DRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVRHFCPNVPIILVGNKKDLRNDEN 73

Query: 125 TIEKLAKNKQKPITPETAEKLARD 148
           T  +L K KQ+P+  +   +  R+
Sbjct: 72  TKRELMKMKQEPVRLDRRARHVRE 1
>17872
          Length = 700

 Score =  153 bits (386), Expect = 5e-38,   Method: Compositional matrix adjust.
 Identities = 73/117 (62%), Positives = 92/117 (78%)
 Frame = -1

Query: 61  QEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPKTPFLLVGTQIDLR 120
           Q+D+D LRPL YP+T+VFL+CFSVVSP+SF NV EKWVPE+ +HCP  P ++VGTQ DLR
Sbjct: 700 QDDFDSLRPLCYPETNVFLLCFSVVSPTSFHNVMEKWVPELRYHCPGAPLVVVGTQSDLR 521

Query: 121 DDPSTIEKLAKNKQKPITPETAEKLARDLKAVKYVECSALTQKGLKNVFDEAILAAL 177
           +D   + +LAK K+KP++ E A K+A  L A +YVECSALTQK LK VFD  ILA+L
Sbjct: 520 NDVKVLIELAKYKEKPVSEEEAVKMADQLGA-QYVECSALTQKNLKEVFDTGILASL 353
>31291
          Length = 446

 Score =  150 bits (379), Expect = 3e-37,   Method: Compositional matrix adjust.
 Identities = 71/142 (50%), Positives = 95/142 (66%), Gaps = 3/142 (2%)
 Frame = -1

Query: 53  LGLFDTAGQEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPKTPFLL 112
           L L+DTAGQEDYDRLRPL+YP TDVF++ FS++S +S +NVK KW PEI HH P  P +L
Sbjct: 446 LQLWDTAGQEDYDRLRPLAYPNTDVFMLXFSLMSEASMKNVKVKWYPEIRHHDPHVPIVL 267

Query: 113 VGTQIDLRDDPSTIEKLAKNKQKPITPETAEKLARDLKAVKYVECSALTQKGLKNVFDEA 172
           VGT++DLR D   + KL  ++Q P++      LA+ +KA +Y ECS+ TQ+ LK  F+E 
Sbjct: 266 VGTKLDLRQDKEAVRKLRSSRQDPVSSNQGNDLAKAIKAKRYFECSSKTQENLKTAFEET 87

Query: 173 ILAALEPPEPKKSR---RCVLL 191
           +  AL        R   +CVLL
Sbjct: 86  VRVALNMDGQNNKRPKPKCVLL 21
>10708
          Length = 2775

 Score = 85.1 bits (209), Expect = 1e-17,   Method: Compositional matrix adjust.
 Identities = 42/118 (35%), Positives = 72/118 (61%), Gaps = 1/118 (0%)
 Frame = -3

Query: 75   TDVFLVCFS-VVSPSSFENVKEKWVPEITHHCPKTPFLLVGTQIDLRDDPSTIEKLAKNK 133
            T +  +C S + + +++    +KW PE+ H CP  P +LVG + DLR+D +T  +L K K
Sbjct: 2653 TQMSSLCASPLTALTAWRTSLKKWTPEVRHFCPNVPIILVGNKKDLRNDENTKRELMKMK 2474

Query: 134  QKPITPETAEKLARDLKAVKYVECSALTQKGLKNVFDEAILAALEPPEPKKSRRCVLL 191
            Q+P+  +    ++  + A  Y+ECSA T++G++ VF+ A  AAL+  + KK   C++L
Sbjct: 2473 QEPVRLDEGRAMSEKINAYSYLECSAKTKEGVREVFETATRAALQTKKKKKG-GCIVL 2303

 Score = 74.7 bits (182), Expect = 2e-14,   Method: Compositional matrix adjust.
 Identities = 35/59 (59%), Positives = 43/59 (72%), Gaps = 7/59 (11%)
 Frame = -2

Query: 53   LGLFDTAGQEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEK-------WVPEITHH 104
            L L+DTAGQEDYDRLRPLSYP TDV L+CFS+ SP S EN+ EK       ++ + +HH
Sbjct: 2717 LALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKVDSRGAPFLSQCSHH 2541
>09700
          Length = 1855

 Score = 83.2 bits (204), Expect = 6e-17,   Method: Compositional matrix adjust.
 Identities = 46/94 (48%), Positives = 61/94 (64%), Gaps = 8/94 (8%)
 Frame = -1

Query: 102  THHCPKTPFLLVGTQIDLRDDPSTIEKLAKNKQKPITPETAEKLARDLKAVKYVECSALT 161
             ++ P+TP +LVGTQ DLR+D   + +LAK K+KP++ + A KLA  L A  YVECSALT
Sbjct: 1834 ANNSPRTPLVLVGTQSDLRNDVKVLIELAKYKEKPVSEDDASKLAHQLGA-SYVECSALT 1658

Query: 162  QKGLKNVFDEAILAALEPPEP--------KKSRR 187
            QK LK +FD  IL +L+  E         +KSRR
Sbjct: 1657 QKNLKEMFDSCILTSLQWAEAELQRSKSVRKSRR 1556
>08428
          Length = 1109

 Score = 72.4 bits (176), Expect = 1e-13,   Method: Compositional matrix adjust.
 Identities = 48/183 (26%), Positives = 91/183 (49%), Gaps = 2/183 (1%)
 Frame = -3

Query: 1    MQTIKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNY-AVTVMIGGEPYTLGLFDTA 59
            M+ +K  ++GD  VGK+ +++ + T  +      T+  ++ + ++++ G  Y   ++DTA
Sbjct: 1077 MRDVKVCLLGDSGVGKSSIVLRFVTGSYRPSQESTIGASFMSKSLVVDGAGYRFQIWDTA 898

Query: 60   GQEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPKTPFL-LVGTQID 118
            GQE +  L P+ Y      ++ + V  P +F++VK  W+ E+    P    L + G + D
Sbjct: 897  GQEKFRALAPMYYRGAAAAVIVYDVTRPRTFKSVK-SWIQELRSFGPPNIVLAIAGNKCD 721

Query: 119  LRDDPSTIEKLAKNKQKPITPETAEKLARDLKAVKYVECSALTQKGLKNVFDEAILAALE 178
            L +    +EK             A++ A  + A+ + E SA+T   ++ +F E  LA   
Sbjct: 720  LEELREVVEK------------DAQEYASSISAI-FGETSAMTAVNVEEMFTE--LARQL 586

Query: 179  PPE 181
            PPE
Sbjct: 585  PPE 577
>17511
          Length = 483

 Score = 67.4 bits (163), Expect = 3e-12,   Method: Compositional matrix adjust.
 Identities = 38/122 (31%), Positives = 66/122 (54%), Gaps = 6/122 (4%)
 Frame = -3

Query: 4   IKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVT-VMIGGEPYTLGLFDTAGQE 62
           +K +++GD  VGKT L+  Y   KF ++Y  T+  ++    VM+     T+ ++DTAGQE
Sbjct: 364 LKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQIWDTAGQE 185

Query: 63  DYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPE-ITHHCPKT----PFLLVGTQI 117
            +  L    Y   D  ++ F V  P++F ++ + W  E +    P+     PF+++G +I
Sbjct: 184 RFQSLGVAFYRGADCCVLVFDVTMPNTFRSL-DSWRDEFLIQASPRDPENFPFVVIGNKI 8

Query: 118 DL 119
           DL
Sbjct: 7   DL 2
>00858
          Length = 1658

 Score = 66.6 bits (161), Expect = 5e-12,   Method: Compositional matrix adjust.
 Identities = 47/156 (30%), Positives = 75/156 (48%), Gaps = 2/156 (1%)
 Frame = -2

Query: 16   KTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAGQEDYDRLRPLSYPQT 75
            K+ L I    N F  EY PT  D+    V+I GE   L + DTAGQE+   +R       
Sbjct: 1552 KSALTIQLXQNHFVEEYDPTXEDSXRKQVVIDGETCLLDILDTAGQEEXSAMRDQCMRTG 1373

Query: 76   DVFLVCFSVVSPSSFENVKEKWVPEITH--HCPKTPFLLVGTQIDLRDDPSTIEKLAKNK 133
            + FL  F+V +  SFE++ + +  +I       + P +LVG ++DL      I  + + +
Sbjct: 1372 EGFLCVFAVXNLKSFEDINQ-YREQIKRVKDADEVPMVLVGNKVDL-----PIRNVEQRQ 1211

Query: 134  QKPITPETAEKLARDLKAVKYVECSALTQKGLKNVF 169
             K +          +L  + YVE SA T++G+ + F
Sbjct: 1210 GKHMA---------ELYHIPYVETSAKTRQGVDDAF 1130
>14456
          Length = 1867

 Score = 65.9 bits (159), Expect = 9e-12,   Method: Compositional matrix adjust.
 Identities = 52/173 (30%), Positives = 82/173 (47%), Gaps = 6/173 (3%)
 Frame = -1

Query: 12   GAVGKTCLLISYTTNKFPSEYVPTVFDNY-AVTVMIGGEPYTLGLFDTAGQEDYDRLRPL 70
            G VGK+ L+  + +NKF ++   T+   +    V++  E YT+ ++DTAGQE +  LR  
Sbjct: 1114 GGVGKSSLMNRFVSNKFDAQSFHTIGVEFLNKDVVVDDETYTMQIWDTAGQERFKSLRTP 935

Query: 71   SYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCP-----KTPFLLVGTQIDLRDDPST 125
             Y   D  L+ FSV S  SF N+   W  E  ++         PF+++G +ID+      
Sbjct: 934  FYRGADCCLLTFSVDSMQSFRNLS-MWRKEFLYYADIQDGVTFPFVVLGNKIDV------ 776

Query: 126  IEKLAKNKQKPITPETAEKLARDLKAVKYVECSALTQKGLKNVFDEAILAALE 178
                   + + +T E A           Y E SA   K   NV ++A LAA++
Sbjct: 775  -------EGRQVTNEEARSWCTANSNAPYFETSA---KDATNV-EKAFLAAVQ 650
>34468
          Length = 1502

 Score = 62.4 bits (150), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 41/135 (30%), Positives = 65/135 (48%), Gaps = 4/135 (2%)
 Frame = +1

Query: 2   QTIKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTV-FDNYAVTVMIGGEPYTLGLFDTAG 60
           +  K +V+GD  VGKTCL   +   KFP +   T+  D    ++ +  E   L L+DTAG
Sbjct: 490 RIFKIIVIGDSNVGKTCLTYRFCLGKFPDKTEATIGVDFREKSIQVDSEHLKLQLWDTAG 669

Query: 61  QEDYDR-LRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHH--CPKTPFLLVGTQI 117
           QE + + +    Y      +  + +   SSFEN+   W+ E   H      P +LVG + 
Sbjct: 670 QERFRKSMVQHYYRNVHAVVFVYDMTKMSSFENMP-AWIEECDRHNLTKYIPRILVGNKC 846

Query: 118 DLRDDPSTIEKLAKN 132
           D+      +E++A N
Sbjct: 847 DV------VERIAVN 873
>01972
          Length = 2359

 Score = 47.8 bits (112), Expect(2) = 2e-10,   Method: Compositional matrix adjust.
 Identities = 23/85 (27%), Positives = 44/85 (51%)
 Frame = +3

Query: 53  LGLFDTAGQEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPKTPFLL 112
             ++DTAGQE +  LR   Y Q    ++ F V S  +++NV   W  ++   C   P +L
Sbjct: 453 FNVWDTAGQEKFGGLRDGYYIQGQCAVIMFDVTSRVTYKNVPN-WHRDLVRVCENIPIVL 629

Query: 113 VGTQIDLRDDPSTIEKLAKNKQKPI 137
            G ++D++D     + +  +++K +
Sbjct: 630 CGNKVDIKDRKVKAKAIVFHRKKNL 704

 Score = 33.9 bits (76), Expect(2) = 2e-10,   Method: Compositional matrix adjust.
 Identities = 14/32 (43%), Positives = 19/32 (59%)
 Frame = +1

Query: 3   TIKCVVVGDGAVGKTCLLISYTTNKFPSEYVP 34
           T K V+VGDG VGKT  +  + T +F    +P
Sbjct: 301 TFKLVLVGDGGVGKTTFVKRHVTGEFEKNMLP 396
>07465
          Length = 1103

 Score = 61.2 bits (147), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 42/154 (27%), Positives = 69/154 (44%), Gaps = 1/154 (0%)
 Frame = +3

Query: 17  TCLLISYTTNKFPSEYVPTV-FDNYAVTVMIGGEPYTLGLFDTAGQEDYDRLRPLSYPQT 75
           + ++  Y    F  +Y  T+  D     + +GGE   L L+DTAGQE++D +    Y   
Sbjct: 240 SSMIQRYCKGIFTKDYKKTIGVDFLERQIEVGGEDVRLMLWDTAGQEEFDAITKAYYRGA 419

Query: 76  DVFLVCFSVVSPSSFENVKEKWVPEITHHCPKTPFLLVGTQIDLRDDPSTIEKLAKNKQK 135
              ++ FS V   SFE + E W  ++     +   ++V  +IDL DD             
Sbjct: 420 QACVLAFSTVDRDSFEAL-ETWKRKVEDEVGEIGMVIVQNKIDLIDDA------------ 560

Query: 136 PITPETAEKLARDLKAVKYVECSALTQKGLKNVF 169
            + PE AE LA+ L+ +++   S      +  VF
Sbjct: 561 VVRPEEAENLAKKLR-LRFYRTSVKENMNVDEVF 659
>32770
          Length = 387

 Score = 59.7 bits (143), Expect = 7e-10,   Method: Compositional matrix adjust.
 Identities = 34/83 (40%), Positives = 47/83 (56%), Gaps = 2/83 (2%)
 Frame = +2

Query: 99  PEITHHCPKTPFLLVGTQIDLR--DDPSTIEKLAKNKQKPITPETAEKLARDLKAVKYVE 156
           PE+  + P TPF+LVGTQ DLR    P++ + +  +K K        KLAR + A+ Y E
Sbjct: 2   PELRDYRPGTPFILVGTQADLRHHSQPASKDMVPAHKGK--------KLARKVGALGYFE 157

Query: 157 CSALTQKGLKNVFDEAILAALEP 179
           CSAL   GL  VF + +  A+ P
Sbjct: 158 CSALIGSGLDRVFRQVVTCAVHP 226
>07580
          Length = 921

 Score = 57.0 bits (136), Expect = 4e-09,   Method: Compositional matrix adjust.
 Identities = 42/173 (24%), Positives = 78/173 (45%), Gaps = 1/173 (0%)
 Frame = +3

Query: 14  VGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAGQEDYDRLRPLSYP 73
           + K   L S     F  +Y PT+ D+Y   V + G+   L + DTAG E +  +R L   
Sbjct: 93  LAKVL*LYSLCKGIFVEKYDPTIEDSYRKQVEVDGQQCMLEILDTAGTEQFTAMRDLYMK 272

Query: 74  QTDVFLVCFSVVSPSSFENVKEKWVPEI-THHCPKTPFLLVGTQIDLRDDPSTIEKLAKN 132
               FL+ +S+ + S+F +++E     +        P LLVG + DL D           
Sbjct: 273 NGQGFLLAYSITAQSTFNDLQELREQILRVKDTDDVPMLLVGNKCDLED----------- 419

Query: 133 KQKPITPETAEKLARDLKAVKYVECSALTQKGLKNVFDEAILAALEPPEPKKS 185
            ++ +  +  + LAR   +  ++E SA  +  +  +F + ++  +    P++S
Sbjct: 420 -ERVVGKDQGQGLARSF-SCAFLETSAKARINVNEIFMD-LVRQINKKSPEQS 569
>26083
          Length = 432

 Score = 54.7 bits (130), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 33/118 (27%), Positives = 59/118 (50%), Gaps = 2/118 (1%)
 Frame = +1

Query: 1   MQTIKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTV-FDNYAVTVMIGGEPYTLGLFDTA 59
           ++  K V +G+ +VGKT L+  +  + F + Y  T+  D  + T+ +      L L+DTA
Sbjct: 70  LRKFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTIRLQLWDTA 249

Query: 60  GQEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEI-THHCPKTPFLLVGTQ 116
           GQE +  L P     + V +V + + + +SF     KW+ ++ T        +LVG +
Sbjct: 250 GQERFRSLIPSYIRDSSVAVVVYDITNANSFHQT-SKWIDDVRTERGSDVIIMLVGNK 420
>11257
          Length = 1102

 Score = 54.3 bits (129), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 38/148 (25%), Positives = 66/148 (44%), Gaps = 5/148 (3%)
 Frame = -2

Query: 44   VMIGGEPYTLGLFDTAGQEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITH 103
            V++ GE +T+ ++DTAGQE Y  LR   Y  TD  L+ FSV +  S +++ + W  E  +
Sbjct: 1047 VVVDGETFTMQIWDTAGQERYKSLRTPFYRGTDCCLLTFSVDNLKSLQSLSD-WYDEFVN 871

Query: 104  HC-----PKTPFLLVGTQIDLRDDPSTIEKLAKNKQKPITPETAEKLARDLKAVKYVECS 158
            +         PF+++G + D+             +++ ++ E A    R    + Y E S
Sbjct: 870  YADIQDSASFPFVIIGNKADI-------------EEREVSSEDAYNWCRTHGNLPYFETS 730

Query: 159  ALTQKGLKNVFDEAILAALEPPEPKKSR 186
            A     ++  F   +    E  E    R
Sbjct: 729  AKDSLNVQQAFLAVVRRLREMDEQMDER 646
>35581
          Length = 364

 Score = 50.8 bits (120), Expect = 4e-07,   Method: Compositional matrix adjust.
 Identities = 31/106 (29%), Positives = 49/106 (46%), Gaps = 2/106 (1%)
 Frame = +2

Query: 4   IKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVT--VMIGGEPYTLGLFDTAGQ 61
            KCV++GD  VGKTCLL    T+KF    + ++     +T   +  G   ++ L+DTAGQ
Sbjct: 47  FKCVLLGDAGVGKTCLLNRLATDKFLDSPLTSLTTASLLTTVTLTSGVMASVDLWDTAGQ 226

Query: 62  EDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPK 107
           E Y  L    Y  T   L+ +         +  ++    + HH  +
Sbjct: 227 ERYRSLTSSYYRDTKAVLIVYDAEHKLKLTDWTDR--AAVPHHTQR 358
>30760
          Length = 596

 Score = 50.1 bits (118), Expect = 6e-07,   Method: Compositional matrix adjust.
 Identities = 43/166 (25%), Positives = 73/166 (43%), Gaps = 11/166 (6%)
 Frame = -1

Query: 5   KCVVVGDGAVGKT--CLLISYTTNKFPSEYVPTVFDNYAVTVMI-------GGEPYTLGL 55
           KC+V GD  VGK+  C +    +  FP  Y  T      V V++         +   L L
Sbjct: 524 KCIVTGDSGVGKSSICQVFHSDSAHFPKNYSMTT----GVEVLVKLVNIPDSRDQVELYL 357

Query: 56  FDTAGQEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPKT--PFLLV 113
           FD+AG+E +       + Q  V +V + V   +SF     +W+  +    P T  P +LV
Sbjct: 356 FDSAGKEIFSENVTKFWDQPSVVMVVYDVTDETSFSGCV-RWLERVRAAKPNTVIPGVLV 180

Query: 114 GTQIDLRDDPSTIEKLAKNKQKPITPETAEKLARDLKAVKYVECSA 159
             + DL            ++++ ++ +  + LA+    ++Y ECSA
Sbjct: 179 ANKTDL------------DERRRVSRKEGKDLAQS-HGLEYFECSA 81
>27191
          Length = 443

 Score = 49.7 bits (117), Expect = 8e-07,   Method: Compositional matrix adjust.
 Identities = 29/104 (27%), Positives = 52/104 (50%), Gaps = 2/104 (1%)
 Frame = +1

Query: 16  KTCLLISYTTNKFPSEYVPTVFDNYAVTVM-IGGEPYTLGLFDTAGQEDYDRLRPLSYPQ 74
           KTCL+  +  +KF   Y PTV  +Y   +  + G    + ++D +G  +Y  +R   Y  
Sbjct: 1   KTCLIKHFCESKFNQGYQPTVGVDYGFKIQTVNGVDMRVHMWDLSGSNEYLDVRNELYTG 180

Query: 75  TDVFLVCFSVVSPSSFENVKEKWVPEITHHCPKTPF-LLVGTQI 117
           +D   + F V +  SFE + + W+ EI      +P  ++VG ++
Sbjct: 181 SDAIFIVFDVSNTPSFEAL-DSWLREINRFATGSPLNVIVGNRV 309
>34359
          Length = 1042

 Score = 47.8 bits (112), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 23/90 (25%), Positives = 46/90 (51%)
 Frame = +3

Query: 53  LGLFDTAGQEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPKTPFLL 112
             ++DTAGQE +  LR   Y Q    ++ F V S  +++NV   W  ++   C   P +L
Sbjct: 201 FNVWDTAGQEKFGGLRDGYYIQGTCAIIMFDVTSRVTYKNVPN-WHRDLVRVCENIPIVL 377

Query: 113 VGTQIDLRDDPSTIEKLAKNKQKPITPETA 142
            G ++D++D     + +  ++++  +  T+
Sbjct: 378 CGNKVDIKDRKVKAKAIVFHRKRTCSTTTS 467
>13901
          Length = 962

 Score = 47.4 bits (111), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 24/90 (26%), Positives = 46/90 (51%), Gaps = 2/90 (2%)
 Frame = -3

Query: 5   KCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEP--YTLGLFDTAGQE 62
           K +++GD  VGKT  +  Y  + F  +Y  T+  ++A+ V+   +     L L+D AGQE
Sbjct: 282 KVIIIGDPTVGKTSFVQRYVNDSFRRDYKMTIGVDFALKVIRWSDKCNIKLQLWDIAGQE 103

Query: 63  DYDRLRPLSYPQTDVFLVCFSVVSPSSFEN 92
            +  +  + Y      +V F +   ++++N
Sbjct: 102 RFTSMTRVYYKDAHACIVMFDLTQKNTYQN 13
>26536
          Length = 829

 Score = 47.0 bits (110), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 37/139 (26%), Positives = 59/139 (42%), Gaps = 2/139 (1%)
 Frame = +2

Query: 55  LFDTAGQEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKE--KWVPEITHHCPKTPFLL 112
             DTAGQE+Y  +R       D F+V +SV   +SF+  +   +W+            +L
Sbjct: 140 FLDTAGQEEYSSMREHYTRSGDGFIVVYSVTDVTSFQEAEAVFRWLTRFQDETS-IHAVL 316

Query: 113 VGTQIDLRDDPSTIEKLAKNKQKPITPETAEKLARDLKAVKYVECSALTQKGLKNVFDEA 172
            G + DL  D            + +TPE   K+A D   + Y E SA T   +  V+   
Sbjct: 317 CGNKTDLTSD------------RKVTPEEGRKMA-DRLGMLYFETSAKTGDNVSQVY-HG 454

Query: 173 ILAALEPPEPKKSRRCVLL 191
           +L ++  P      + V+L
Sbjct: 455 LLRSI--PRSGTDYKIVML 505

 Score = 42.4 bits (98), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 18/46 (39%), Positives = 28/46 (60%)
 Frame = +2

Query: 5   KCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEP 50
           K V++G G VGK+ L I +T + F   Y PT+ D+Y   + + G+P
Sbjct: 491 KIVMLGSGGVGKSSLTIRFTQDTFLDVYDPTIEDSYRKMIQVSGQP 628
>36757
          Length = 359

 Score = 46.2 bits (108), Expect = 8e-06,   Method: Compositional matrix adjust.
 Identities = 22/26 (84%), Positives = 23/26 (88%)
 Frame = +2

Query: 152 VKYVECSALTQKGLKNVFDEAILAAL 177
           VKY+ECSALTQKGLK VFDEAI A L
Sbjct: 2   VKYLECSALTQKGLKTVFDEAIRAVL 79
>13750
          Length = 503

 Score = 45.1 bits (105), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 45/171 (26%), Positives = 67/171 (39%), Gaps = 8/171 (4%)
 Frame = -2

Query: 16  KTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYT------LGLFDTAGQEDYDRLRP 69
           KTCLL  Y    F    +PT+    AV      E  T        L+DT G E Y  L  
Sbjct: 502 KTCLLRRYQKGFFMDRTMPTI----AVLCSEFNESRTDPLNVRYTLWDTGGAETYRSLWV 335

Query: 70  LSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPKTPFLLVGTQIDLRDDPSTIEKL 129
             +    V L+ + V    SF      W   +  + P+   + VG++ DL ++       
Sbjct: 334 SHFRGAQVALLVYDVTCEWSFLTATTVWRKALMKNIPEAQVIFVGSKTDLEEN------- 176

Query: 130 AKNKQKPITPETAEKLARDLKAVKYVECSALTQKGLKNVFDEA--ILAALE 178
                + I+ E  +  A       + E S++T K +  VF E   ILA L+
Sbjct: 175 -----RVISTERGQAFATQC-GYTFFETSSVTGKNVDAVFWEIAFILARLQ 41
>05468
          Length = 1558

 Score = 44.7 bits (104), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 28/99 (28%), Positives = 47/99 (47%), Gaps = 2/99 (2%)
 Frame = -3

Query: 5    KCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEP--YTLGLFDTAGQE 62
            K +V+G+   GKT ++  Y    F   Y  T+  ++A+ V+         L L+D AGQE
Sbjct: 1535 KILVIGELGTGKTSIIKRYVHQFFSQHYRATIGVDFALKVLNWDADTLIRLQLWDIAGQE 1356

Query: 63   DYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEI 101
             +  +  + Y +     V F V   S+F+ V  KW  ++
Sbjct: 1355 RFGNMTRVYYKEAVGAFVVFDVTRASTFDAVT-KWKNDL 1242
>33794
          Length = 779

 Score = 43.1 bits (100), Expect = 6e-05,   Method: Compositional matrix adjust.
 Identities = 22/78 (28%), Positives = 44/78 (56%), Gaps = 1/78 (1%)
 Frame = -1

Query: 43  TVMIGGEPYTLGLFDTAGQEDY-DRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEI 101
           T+++ G+   L ++DT+GQ  +   +R  S     + LV + + +  SF+ + ++W+ E+
Sbjct: 674 TILLEGKRVKLQIWDTSGQGRFCTIIRSYSRGAQGIILV-YDITNKWSFDGI-DRWLKEV 501

Query: 102 THHCPKTPFLLVGTQIDL 119
             H P  P +LVG ++ L
Sbjct: 500 EEHAPGIPKVLVGNRLHL 447
>09204
          Length = 1051

 Score = 42.7 bits (99), Expect = 9e-05,   Method: Compositional matrix adjust.
 Identities = 27/107 (25%), Positives = 51/107 (47%), Gaps = 1/107 (0%)
 Frame = -3

Query: 64   YDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPKTPFLLVGTQIDL-RDD 122
            Y+ +  + Y      ++CF +   SSF+ ++  W+ E+  H  +    + GT+ DL  DD
Sbjct: 1046 YEAMSRIYYRGAKAAILCFDLTDKSSFDRIR-FWIGELRQHEEECKLYICGTKFDLVHDD 870

Query: 123  PSTIEKLAKNKQKPITPETAEKLARDLKAVKYVECSALTQKGLKNVF 169
            P         +++ +    A+ LA D  A  Y E S++T   ++ +F
Sbjct: 869  P---------ERRAVPRSVAKALADDCMAEIY-ETSSMTGDNIEKLF 759
>33374
          Length = 489

 Score = 42.0 bits (97), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 27/94 (28%), Positives = 40/94 (42%), Gaps = 1/94 (1%)
 Frame = +1

Query: 29  PSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAGQEDYDRLRPLSYPQTDVFLVCFSVVSPS 88
           P EY  + F     TV +        ++DTAGQE Y  L P+ Y      +V + + +  
Sbjct: 115 PGEYDWSCF--LTQTVCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNQD 288

Query: 89  SFENVKEKWVPEITHHC-PKTPFLLVGTQIDLRD 121
           +F   K  WV E+     P     L G + DL +
Sbjct: 289 TFGRAK-TWVKELQRQASPNIVIALAGNKADLAN 387
>33380
          Length = 282

 Score = 41.2 bits (95), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 23/71 (32%), Positives = 36/71 (50%), Gaps = 1/71 (1%)
 Frame = +3

Query: 53  LGLFDTAGQEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEI-THHCPKTPFL 111
           L ++DTAGQE Y  +    Y     F++ + V +  SF N  + W  +I T+       +
Sbjct: 66  LQIWDTAGQERYRTITTAYYRGAMGFILMYDVTNEESF-NAVQDWCTQIKTYSWDNAQVV 242

Query: 112 LVGTQIDLRDD 122
           LVG + DL D+
Sbjct: 243 LVGNKCDLEDE 275
>01398
          Length = 1421

 Score = 40.0 bits (92), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 28/110 (25%), Positives = 54/110 (49%), Gaps = 5/110 (4%)
 Frame = -2

Query: 65   DRLRPL--SYPQTDV-FLVCFSVVSPSSFENVKEKWVPEITHHCP--KTPFLLVGTQIDL 119
            +R R +  SY +  V  ++ + +   S+FEN+K+ W  E  +H    K  FL++G + D 
Sbjct: 1417 ERFRSITRSYYRNSVGVIIVYDITKRSTFENLKQ-WYEEARNHIEPHKAIFLVLGHKSD- 1244

Query: 120  RDDPSTIEKLAKNKQKPITPETAEKLARDLKAVKYVECSALTQKGLKNVF 169
            R+D            + +T     + A ++  +K+ E SA +   +++VF
Sbjct: 1243 REDA-----------RQVTAREGRRFA-EMHGLKFFETSAKSGHNIEDVF 1130
>00552
          Length = 455

 Score = 39.3 bits (90), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 17/51 (33%), Positives = 32/51 (62%), Gaps = 1/51 (1%)
 Frame = -1

Query: 4   IKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVT-VMIGGEPYTL 53
           +K V++GDG VGK+ L+  + +NKF ++   T+   +    V++ GE +T+
Sbjct: 443 LKVVLLGDGGVGKSSLMNRFVSNKFDAQSFHTIGVEFLTKDVVVDGETFTM 291

 Score = 37.7 bits (86), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 20/51 (39%), Positives = 30/51 (58%)
 Frame = -3

Query: 54  GLFDTAGQEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHH 104
           G++DTAGQE Y  LR   Y  TD  L+ FSV +  S +++ + W  E  ++
Sbjct: 150 GIWDTAGQERYKSLRTPFYRGTDCCLLTFSVDNLKSLQSLSD-WYDEFVNY 1
>36482
          Length = 686

 Score = 35.8 bits (81), Expect = 0.011,   Method: Compositional matrix adjust.
 Identities = 30/120 (25%), Positives = 49/120 (40%), Gaps = 1/120 (0%)
 Frame = +2

Query: 19  LLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAGQEDYDRLRPLSYPQTDVF 78
           L + + T +F  EY PT+   Y    +I  +   L + DTAGQ  Y      +    D F
Sbjct: 2   LTVRFLTRRFIGEYCPTLESVYKYHTVIEDDDVRLEILDTAGQGTYPWKEGYALW-ADCF 178

Query: 79  LVCFSVVSPSSFEN-VKEKWVPEITHHCPKTPFLLVGTQIDLRDDPSTIEKLAKNKQKPI 137
           +  +S+    S+E  V+ K   E          +L   + DL  D    +K  ++  + I
Sbjct: 179 VFVYSINDRQSYEELVQVKRQVESVRKSTSLTAVLAANKTDLLHDRQVTQKEGEDLAEEI 358
>24619
          Length = 509

 Score = 32.0 bits (71), Expect = 0.18,   Method: Compositional matrix adjust.
 Identities = 27/100 (27%), Positives = 44/100 (44%), Gaps = 1/100 (1%)
 Frame = -2

Query: 61  QEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPKT-PFLLVGTQIDL 119
           QE++  +R     + D FL+ FSV+   SFEN+       +      T P +L   ++DL
Sbjct: 508 QEEFSAMREQYMRKGDGFLLVFSVIDYQSFENMVNFHTQILRVKDRDTYPMILCANKVDL 329

Query: 120 RDDPSTIEKLAKNKQKPITPETAEKLARDLKAVKYVECSA 159
                         Q+ ++ E    LA  L+ + Y+E SA
Sbjct: 328 ------------VHQRKVSEEQVRDLATRLR-IPYIETSA 248
>19046
          Length = 445

 Score = 30.4 bits (67), Expect = 0.46,   Method: Compositional matrix adjust.
 Identities = 27/101 (26%), Positives = 45/101 (44%), Gaps = 2/101 (1%)
 Frame = -2

Query: 61  QEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPKT--PFLLVGTQID 118
           QE++  +R     + D FL+ FSV    SFEN+   +  +I     +   P +L   ++D
Sbjct: 444 QEEFSAMREQYMRKGDGFLLVFSVTDFRSFENMAN-FHTQILRVKDRDSYPMILCANKVD 268

Query: 119 LRDDPSTIEKLAKNKQKPITPETAEKLARDLKAVKYVECSA 159
           L              Q+ ++ E    LA  L+ + Y+E SA
Sbjct: 267 L------------VHQRKVSEEQVRDLATRLR-IPYIETSA 184
>06994
          Length = 429

 Score = 28.9 bits (63), Expect = 1.4,   Method: Compositional matrix adjust.
 Identities = 21/97 (21%), Positives = 37/97 (38%), Gaps = 32/97 (32%)
 Frame = +1

Query: 31  EYVPTVFDNYAVTVMIGGEPYTLGLFDTAG------------------------------ 60
           +Y PT+ D+Y   V + G+   L + DTAG                              
Sbjct: 139 KYDPTIEDSYRKQVEVDGQQCMLEILDTAGTVHASHSNACVHGSLHAFVGTVTPLGRDAL 318

Query: 61  --QEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKE 95
              E +  +R L       FL+ +S+ + S+F +++E
Sbjct: 319 LNTEQFTAMRDLYMKNGQGFLLAYSITAQSTFNDLQE 429
>21806
          Length = 1553

 Score = 26.9 bits (58), Expect = 4.5,   Method: Compositional matrix adjust.
 Identities = 21/68 (30%), Positives = 28/68 (41%)
 Frame = +2

Query: 77  VFLVCFSVVSPSSFENVKEKWVPEITHHCPKTPFLLVGTQIDLRDDPSTIEKLAKNKQKP 136
           VFLVCF                P+ T+          GT+     D +T+ +   NKQ P
Sbjct: 23  VFLVCF---------------FPQFTN*QA-----TQGTEQRASGDKATMGRRKTNKQAP 142

Query: 137 ITPETAEK 144
           +T E AEK
Sbjct: 143 LTKEGAEK 166
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|158937300|ref|NP_694695.3| SEC63-like protein [Mus
musculus]
         (760 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

35300                                                                 261   7e-70
26868                                                                  81   2e-18
02324                                                                  45   9e-05
02088                                                                  40   0.004
13998                                                                  39   0.005
26984                                                                  36   0.048
07620                                                                  35   0.13 
15360                                                                  32   1.0  
20155                                                                  31   2.3  
33510                                                                  30   4.9  
>35300
          Length = 586

 Score =  261 bits (667), Expect = 7e-70,   Method: Compositional matrix adjust.
 Identities = 122/194 (62%), Positives = 153/194 (78%), Gaps = 1/194 (0%)
 Frame = -1

Query: 138 DEVMFMRIAKAYAALTDEESRKNWEEFGNPDGPQATSFGIALPAWIVDQKNSILVLLVYG 197
           DE  FM+IAKAYAALTDEESRKNWEEFGNPDGP+AT FGIALP WIV+++NS+ VL VYG
Sbjct: 586 DEKRFMKIAKAYAALTDEESRKNWEEFGNPDGPEATRFGIALPKWIVERENSMWVLAVYG 407

Query: 198 LAFMVILPVVVGSWWYRSIRYSGDQILIRTTQIYTYFVYKTRNMDMKRLIMVLAGASEFD 257
           L FM+ILP+VVG WWYRSI++S DQ+L+ TT++Y YF+ KT NM +KR +M+LA + EFD
Sbjct: 406 LVFMIILPIVVGVWWYRSIKFSSDQVLLDTTRLYYYFINKTPNMILKRAVMILAASCEFD 227

Query: 258 PQYNKDSTSRPTDNILIPQLIREIGSINLKKNEPPLTCPYSLKARVLLLSHLARMKIPE- 316
             +N +   RP+DN  +PQLI+ +G++  K  E PL  PYSLK RVLLLSH  R+ +PE 
Sbjct: 226 RMHNAEVQDRPSDNEELPQLIKLLGNVQEKNRERPLCFPYSLKTRVLLLSHFQRLPLPEH 47

Query: 317 TLEEDQQFMLKKCP 330
           TL  DQ ++LKKCP
Sbjct: 46  TLGADQDYILKKCP 5
>26868
          Length = 686

 Score = 80.9 bits (198), Expect(2) = 2e-18,   Method: Composition-based stats.
 Identities = 42/95 (44%), Positives = 64/95 (67%)
 Frame = -2

Query: 383 PLLQLPHIEEDNLRRVSNHKKYKIKTIQDLVSLKESDRHSLLHFLEDEKYEEVMAVLGSF 442
           PL QLPHI  D LR  +  K+  I+ ++D V +++ DR  +L  L + +Y++++ V  + 
Sbjct: 622 PLQQLPHISPDMLRHFTTRKR-NIRHMRDFVMMEDEDRRQMLRSLSEWEYQDILQVCRTL 446

Query: 443 PYVTMDIKSQVLDDEDSNNITVGSLVTVLVKLTRQ 477
           P+V M I+S+VLD+EDS  ITVGS+VTV V L R+
Sbjct: 445 PFVDMSIRSEVLDEEDS-TITVGSIVTVTVNLVRK 344

 Score = 30.4 bits (67), Expect(2) = 2e-18,   Method: Compositional matrix adjust.
 Identities = 14/22 (63%), Positives = 17/22 (77%)
 Frame = -3

Query: 362 SLENCMKLSQMAVQGLQQFKSP 383
           ++EN MKLSQM VQGL +  SP
Sbjct: 684 TVENLMKLSQMMVQGLDEKASP 619
>02324
          Length = 2058

 Score = 45.4 bits (106), Expect = 9e-05,   Method: Compositional matrix adjust.
 Identities = 25/58 (43%), Positives = 34/58 (58%), Gaps = 5/58 (8%)
 Frame = +2

Query: 106 YEVLNLDPGATVAEIKKQYRLLSLKYHPDKGGDEV-----MFMRIAKAYAALTDEESR 158
           YEVL ++  A   ++KK YR L+LK+HPDK  D V      F  + +AY  LTD + R
Sbjct: 110 YEVLGVERSADNDDLKKAYRKLALKFHPDKNPDSVEEATAQFRLVQQAYEILTDPQER 283
>02088
          Length = 1062

 Score = 40.0 bits (92), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 23/72 (31%), Positives = 36/72 (50%), Gaps = 6/72 (8%)
 Frame = +3

Query: 100 YQEYNPYEVLNLDPGATVAEIKKQYRLLSLKYHPD------KGGDEVMFMRIAKAYAALT 153
           ++  + YEV+ +   AT  E+KK Y  +SL  HPD      K      F  + K Y  L+
Sbjct: 96  FETTDLYEVIGIRREATPQEVKKGYHKVSLAVHPDQVSAAEKETATRKFQTLGKVYTVLS 275

Query: 154 DEESRKNWEEFG 165
           D++ R  ++E G
Sbjct: 276 DKDKRAXYDETG 311
>13998
          Length = 1075

 Score = 39.3 bits (90), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 21/66 (31%), Positives = 35/66 (53%), Gaps = 9/66 (13%)
 Frame = +1

Query: 106 YEVLNLDPGATVAEIKKQYRLLSLKYHPDKGGD---------EVMFMRIAKAYAALTDEE 156
           Y++L +   AT  EIKK YR  +L +HPD+  +         E+ F  + +AYA L+D  
Sbjct: 211 YKILGISRNATEDEIKKAYRKKALVHHPDRHANSSADVRKDEELKFKEVGEAYAILSDGA 390

Query: 157 SRKNWE 162
            +  ++
Sbjct: 391 KKTRYD 408
>26984
          Length = 1107

 Score = 36.2 bits (82), Expect = 0.048,   Method: Compositional matrix adjust.
 Identities = 20/62 (32%), Positives = 32/62 (51%), Gaps = 3/62 (4%)
 Frame = -2

Query: 104 NPYEVLNLDPGATVAEIKKQYRLLSLKYHPDKG---GDEVMFMRIAKAYAALTDEESRKN 160
           +PY +L L   A+  +IK+ YR  ++  HPDK    G E  F  +  A+  + D   RK 
Sbjct: 515 DPYSILGLRADASDEDIKRYYRRQAVLVHPDKNQEPGAEEAFKILGHAFEMIGDPTKRKE 336

Query: 161 WE 162
           ++
Sbjct: 335 YD 330
>07620
          Length = 1775

 Score = 34.7 bits (78), Expect = 0.13,   Method: Compositional matrix adjust.
 Identities = 15/30 (50%), Positives = 22/30 (73%)
 Frame = +1

Query: 106 YEVLNLDPGATVAEIKKQYRLLSLKYHPDK 135
           YEVL++    T +++KK YR L+L+ HPDK
Sbjct: 106 YEVLDVKKDCTESDMKKAYRKLALQMHPDK 195
>15360
          Length = 502

 Score = 32.0 bits (71), Expect = 1.0,   Method: Compositional matrix adjust.
 Identities = 18/70 (25%), Positives = 39/70 (55%), Gaps = 12/70 (17%)
 Frame = +1

Query: 106 YEVLNLDPGATVAEIKKQYRLLSLKYHPDKGGDEV----MFMRIAKAY--------AALT 153
           + +L++  G+    +K +Y+ L+LK+HP+K  +       F+++ +AY         A+T
Sbjct: 61  FNLLDIPAGSDQESLKTKYKQLALKWHPEKHKNAAEAVKQFIQVTQAYRLLAYNTSQAMT 240

Query: 154 DEESRKNWEE 163
             E+RK +++
Sbjct: 241 VGEARKFFQD 270
>20155
          Length = 484

 Score = 30.8 bits (68), Expect = 2.3,   Method: Composition-based stats.
 Identities = 12/41 (29%), Positives = 24/41 (58%)
 Frame = +1

Query: 108 VLNLDPGATVAEIKKQYRLLSLKYHPDKGGDEVMFMRIAKA 148
           +L + P A+  +IK  ++ + L  HPD+GG   +  ++ +A
Sbjct: 151 ILGVSPSASKVKIKDAHKRIMLLNHPDRGGSPYLAAKVNEA 273
>33510
          Length = 501

 Score = 29.6 bits (65), Expect = 4.9,   Method: Compositional matrix adjust.
 Identities = 16/47 (34%), Positives = 24/47 (51%), Gaps = 7/47 (14%)
 Frame = +3

Query: 116 TVAEIKKQYRLLSLKYHPDKGGDE-------VMFMRIAKAYAALTDE 155
           +  ++KK YR   L  HPDK  D+       ++FM +  A+A   DE
Sbjct: 294 SADQVKKVYRKAVLSVHPDKLHDDPHEALAKLIFMELNDAWAKFEDE 434
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|194440734|ref|NP_032310.2| Harvey rat sarcoma virus
oncogene 1 isoform 1 [Mus musculus]
         (189 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

00858                                                                 259   7e-70
07580                                                                 172   4e-46
18509                                                                 105   2e-33
19046                                                                 106   6e-24
24619                                                                 103   4e-23
11257                                                                  97   3e-21
36482                                                                  92   1e-19
26536                                                                  90   4e-19
14456                                                                  86   1e-17
06994                                                                  74   2e-17
08428                                                                  79   2e-15
34468                                                                  78   2e-15
33374                                                                  69   1e-12
11728                                                                  67   6e-12
01972                                                                  64   5e-11
30760                                                                  64   5e-11
07465                                                                  63   7e-11
19656                                                                  60   4e-10
01398                                                                  60   5e-10
33794                                                                  59   1e-09
13745                                                                  59   1e-09
33380                                                                  59   2e-09
17511                                                                  58   2e-09
19006                                                                  57   3e-09
12339                                                                  57   3e-09
29380                                                                  55   3e-08
34359                                                                  54   3e-08
26083                                                                  53   8e-08
34597                                                                  52   2e-07
31291                                                                  51   3e-07
10708                                                                  39   4e-07
01095                                                                  50   4e-07
25655                                                                  34   1e-05
14119                                                                  45   2e-05
25618                                                                  45   2e-05
00552                                                                  37   0.004
31928                                                                  36   0.011
21396                                                                  32   0.13 
35581                                                                  30   0.48 
33373                                                                  27   3.6  
30463                                                                  27   5.8  
18949                                                                  26   8.3  
>00858
          Length = 1658

 Score =  259 bits (661), Expect = 7e-70,   Method: Compositional matrix adjust.
 Identities = 128/163 (78%), Positives = 137/163 (84%)
 Frame = -2

Query: 1    MTEYKLXXXXXXXXXKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAG 60
            MTEYKL         KSALTIQL QNHFV+EYDPT EDS RKQVVIDGETCLLDILDTAG
Sbjct: 1597 MTEYKLVVVGAGGVGKSALTIQLXQNHFVEEYDPTXEDSXRKQVVIDGETCLLDILDTAG 1418

Query: 61   QEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLVGNKCDL 120
            QEE SAMRDQ MRTGEGFLCVFA+ N KSFEDI+QYREQIKRVKD+D+VPMVLVGNK DL
Sbjct: 1417 QEEXSAMRDQCMRTGEGFLCVFAVXNLKSFEDINQYREQIKRVKDADEVPMVLVGNKVDL 1238

Query: 121  AARTVESRQAQDLARSYGIPYIETSAKTRQGVEDAFYTLVREI 163
              R VE RQ + +A  Y IPY+ETSAKTRQGV+DAFYTLVREI
Sbjct: 1237 PIRNVEQRQGKHMAELYHIPYVETSAKTRQGVDDAFYTLVREI 1109
>07580
          Length = 921

 Score =  172 bits (436), Expect(2) = 4e-46,   Method: Compositional matrix adjust.
 Identities = 86/164 (52%), Positives = 113/164 (68%), Gaps = 1/164 (0%)
 Frame = +3

Query: 23  LIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVF 82
           L +  FV++YDPTIEDSYRKQV +DG+ C+L+ILDTAG E+++AMRD YM+ G+GFL  +
Sbjct: 120 LCKGIFVEKYDPTIEDSYRKQVEVDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFLLAY 299

Query: 83  AINNTKSFEDIHQYREQIKRVKDSDDVPMVLVGNKCDLA-ARTVESRQAQDLARSYGIPY 141
           +I    +F D+ + REQI RVKD+DDVPM+LVGNKCDL   R V   Q Q LARS+   +
Sbjct: 300 SITAQSTFNDLQELREQILRVKDTDDVPMLLVGNKCDLEDERVVGKDQGQGLARSFSCAF 479

Query: 142 IETSAKTRQGVEDAFYTLVREIRQHKLRKLNPPDESGPGCMSCK 185
           +ETSAK R  V + F  LVR+I +        P++SG    S K
Sbjct: 480 LETSAKARINVNEIFMDLVRQINKK------SPEQSGKRTKSKK 593

 Score = 29.3 bits (64), Expect(2) = 4e-46,   Method: Compositional matrix adjust.
 Identities = 13/28 (46%), Positives = 15/28 (53%)
 Frame = +2

Query: 1  MTEYKLXXXXXXXXXKSALTIQLIQNHF 28
          M EYKL         KSALT+Q +Q  F
Sbjct: 53 MREYKLVVLGSGGVGKSALTVQFVQGDF 136
>18509
          Length = 625

 Score =  105 bits (263), Expect(2) = 2e-33,   Method: Compositional matrix adjust.
 Identities = 50/69 (72%), Positives = 58/69 (84%)
 Frame = -3

Query: 102 RVKDSDDVPMVLVGNKCDLAARTVESRQAQDLARSYGIPYIETSAKTRQGVEDAFYTLVR 161
           RVKD+D+VPMVLVGNK DL  R VE RQ + +A  Y IPY+ETSAKTRQGV+DAFYTLVR
Sbjct: 548 RVKDADEVPMVLVGNKVDLPIRNVEQRQGKHMAELYHIPYVETSAKTRQGVDDAFYTLVR 369

Query: 162 EIRQHKLRK 170
           EIR++K RK
Sbjct: 368 EIRKYKERK 342

 Score = 53.5 bits (127), Expect(2) = 2e-33,   Method: Compositional matrix adjust.
 Identities = 23/26 (88%), Positives = 25/26 (96%)
 Frame = -1

Query: 76  EGFLCVFAINNTKSFEDIHQYREQIK 101
           EGFLCVFA+NN KSFEDI+QYREQIK
Sbjct: 625 EGFLCVFAVNNLKSFEDINQYREQIK 548
>19046
          Length = 445

 Score =  106 bits (264), Expect = 6e-24,   Method: Compositional matrix adjust.
 Identities = 56/106 (52%), Positives = 71/106 (66%), Gaps = 2/106 (1%)
 Frame = -2

Query: 61  QEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLVGNKCDL 120
           QEE+SAMR+QYMR G+GFL VF++ + +SFE++  +  QI RVKD D  PM+L  NK DL
Sbjct: 444 QEEFSAMREQYMRKGDGFLLVFSVTDFRSFENMANFHTQILRVKDRDSYPMILCANKVDL 265

Query: 121 A-ARTVESRQAQDLARSYGIPYIETSAKTRQ-GVEDAFYTLVREIR 164
              R V   Q +DLA    IPYIETSAK     V+ AF+ +VR IR
Sbjct: 264 VHQRKVSEEQVRDLATRLRIPYIETSAKDPPLNVDLAFHQVVRVIR 127
>24619
          Length = 509

 Score =  103 bits (257), Expect = 4e-23,   Method: Compositional matrix adjust.
 Identities = 56/106 (52%), Positives = 71/106 (66%), Gaps = 2/106 (1%)
 Frame = -2

Query: 61  QEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLVGNKCDL 120
           QEE+SAMR+QYMR G+GFL VF++ + +SFE++  +  QI RVKD D  PM+L  NK DL
Sbjct: 508 QEEFSAMREQYMRKGDGFLLVFSVIDYQSFENMVNFHTQILRVKDRDTYPMILCANKVDL 329

Query: 121 A-ARTVESRQAQDLARSYGIPYIETSAKTRQ-GVEDAFYTLVREIR 164
              R V   Q +DLA    IPYIETSAK     V+ AF+ +VR IR
Sbjct: 328 VHQRKVSEEQVRDLATRLRIPYIETSAKDPPLNVDLAFHQVVRVIR 191
>11257
          Length = 1102

 Score = 97.4 bits (241), Expect = 3e-21,   Method: Compositional matrix adjust.
 Identities = 49/128 (38%), Positives = 76/128 (59%), Gaps = 4/128 (3%)
 Frame = -2

Query: 42   KQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIK 101
            K VV+DGET  + I DTAGQE Y ++R  + R  +  L  F+++N KS + +  + ++  
Sbjct: 1053 KDVVVDGETFTMQIWDTAGQERYKSLRTPFYRGTDCCLLTFSVDNLKSLQSLSDWYDEFV 874

Query: 102  R---VKDSDDVPMVLVGNKCDLAARTVESRQAQDLARSYG-IPYIETSAKTRQGVEDAFY 157
                ++DS   P V++GNK D+  R V S  A +  R++G +PY ETSAK    V+ AF 
Sbjct: 873  NYADIQDSASFPFVIIGNKADIEEREVSSEDAYNWCRTHGNLPYFETSAKDSLNVQQAFL 694

Query: 158  TLVREIRQ 165
             +VR +R+
Sbjct: 693  AVVRRLRE 670
>36482
          Length = 686

 Score = 92.0 bits (227), Expect = 1e-19,   Method: Compositional matrix adjust.
 Identities = 53/153 (34%), Positives = 85/153 (55%), Gaps = 4/153 (2%)
 Frame = +2

Query: 19  LTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGF 78
           LT++ +   F+ EY PT+E  Y+   VI+ +   L+ILDTAGQ  Y   ++ Y    + F
Sbjct: 2   LTVRFLTRRFIGEYCPTLESVYKYHTVIEDDDVRLEILDTAGQGTY-PWKEGYALWADCF 178

Query: 79  LCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLVGNKCDLAA-RTVESRQAQDLARSY 137
           + V++IN+ +S+E++ Q + Q++ V+ S  +  VL  NK DL   R V  ++ +DLA   
Sbjct: 179 VFVYSINDRQSYEELVQVKRQVESVRKSTSLTAVLAANKTDLLHDRQVTQKEGEDLAEEI 358

Query: 138 GIPYIETSA---KTRQGVEDAFYTLVREIRQHK 167
           G    E SA      + +   F+ L RE R+HK
Sbjct: 359 GCRLYEVSASEGSQMEAITSMFHDLYREFRKHK 457
>26536
          Length = 829

 Score = 89.7 bits (221), Expect(2) = 4e-19,   Method: Compositional matrix adjust.
 Identities = 44/110 (40%), Positives = 66/110 (60%), Gaps = 1/110 (0%)
 Frame = +2

Query: 55  ILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLV 114
            LDTAGQEEYS+MR+ Y R+G+GF+ V+++ +  SF++       + R +D   +  VL 
Sbjct: 140 FLDTAGQEEYSSMREHYTRSGDGFIVVYSVTDVTSFQEAEAVFRWLTRFQDETSIHAVLC 319

Query: 115 GNKCDLAA-RTVESRQAQDLARSYGIPYIETSAKTRQGVEDAFYTLVREI 163
           GNK DL + R V   + + +A   G+ Y ETSAKT   V   ++ L+R I
Sbjct: 320 GNKTDLTSDRKVTPEEGRKMADRLGMLYFETSAKTGDNVSQVYHGLLRSI 469

 Score = 21.2 bits (43), Expect(2) = 4e-19,   Method: Compositional matrix adjust.
 Identities = 8/13 (61%), Positives = 8/13 (61%)
 Frame = +1

Query: 48  GETCLLDILDTAG 60
           GETC LDI    G
Sbjct: 118 GETCFLDIFGHRG 156

 Score = 51.6 bits (122), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 23/48 (47%), Positives = 32/48 (66%)
 Frame = +2

Query: 2   TEYKLXXXXXXXXXKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGE 49
           T+YK+         KS+LTI+  Q+ F+D YDPTIEDSYRK + + G+
Sbjct: 482 TDYKIVMLGSGGVGKSSLTIRFTQDTFLDVYDPTIEDSYRKMIQVSGQ 625
>14456
          Length = 1867

 Score = 85.5 bits (210), Expect = 1e-17,   Method: Compositional matrix adjust.
 Identities = 50/155 (32%), Positives = 84/155 (54%), Gaps = 5/155 (3%)
 Frame = -1

Query: 16   KSALTIQLIQNHFVDEYDPTIEDSY-RKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRT 74
            KS+L  + + N F  +   TI   +  K VV+D ET  + I DTAGQE + ++R  + R 
Sbjct: 1102 KSSLMNRFVSNKFDAQSFHTIGVEFLNKDVVVDDETYTMQIWDTAGQERFKSLRTPFYRG 923

Query: 75   GEGFLCVFAINNTKSFEDIHQYREQI---KRVKDSDDVPMVLVGNKCDLAARTVESRQAQ 131
             +  L  F++++ +SF ++  +R++      ++D    P V++GNK D+  R V + +A+
Sbjct: 922  ADCCLLTFSVDSMQSFRNLSMWRKEFLYYADIQDGVTFPFVVLGNKIDVEGRQVTNEEAR 743

Query: 132  DL-ARSYGIPYIETSAKTRQGVEDAFYTLVREIRQ 165
                 +   PY ETSAK    VE AF   V+ +R+
Sbjct: 742  SWCTANSNAPYFETSAKDATNVEKAFLAAVQRLRE 638
>06994
          Length = 429

 Score = 73.9 bits (180), Expect(2) = 2e-17,   Method: Compositional matrix adjust.
 Identities = 38/105 (36%), Positives = 54/105 (51%), Gaps = 32/105 (30%)
 Frame = +1

Query: 23  LIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAG---------------------- 60
           L +     +YDPTIEDSYRKQV +DG+ C+L+ILDTAG                      
Sbjct: 115 LCKGFLWKKYDPTIEDSYRKQVEVDGQQCMLEILDTAGTVHASHSNACVHGSLHAFVGTV 294

Query: 61  ----------QEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQ 95
                      E+++AMRD YM+ G+GFL  ++I    +F D+ +
Sbjct: 295 TPLGRDALLNTEQFTAMRDLYMKNGQGFLLAYSITAQSTFNDLQE 429

 Score = 31.2 bits (69), Expect(2) = 2e-17,   Method: Compositional matrix adjust.
 Identities = 14/31 (45%), Positives = 18/31 (58%)
 Frame = +3

Query: 1  MTEYKLXXXXXXXXXKSALTIQLIQNHFVDE 31
          M EYKL         KSALT+Q +Q  FV++
Sbjct: 48 MREYKLVVLGSGGVGKSALTVQFVQGIFVEK 140
>08428
          Length = 1109

 Score = 78.6 bits (192), Expect = 2e-15,   Method: Compositional matrix adjust.
 Identities = 48/166 (28%), Positives = 83/166 (50%), Gaps = 2/166 (1%)
 Frame = -3

Query: 16   KSALTIQLIQNHFVDEYDPTIEDSY-RKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRT 74
            KS++ ++ +   +    + TI  S+  K +V+DG      I DTAGQE++ A+   Y R 
Sbjct: 1032 KSSIVLRFVTGSYRPSQESTIGASFMSKSLVVDGAGYRFQIWDTAGQEKFRALAPMYYRG 853

Query: 75   GEGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLVGNKCDLAA-RTVESRQAQDL 133
                + V+ +   ++F+ +  + ++++     + V + + GNKCDL   R V  + AQ+ 
Sbjct: 852  AAAAVIVYDVTRPRTFKSVKSWIQELRSFGPPNIV-LAIAGNKCDLEELREVVEKDAQEY 676

Query: 134  ARSYGIPYIETSAKTRQGVEDAFYTLVREIRQHKLRKLNPPDESGP 179
            A S    + ETSA T   VE+ F  L R++         PP+E  P
Sbjct: 675  ASSISAIFGETSAMTAVNVEEMFTELARQL---------PPEEDNP 565
>34468
          Length = 1502

 Score = 78.2 bits (191), Expect = 2e-15,   Method: Compositional matrix adjust.
 Identities = 53/163 (32%), Positives = 81/163 (49%), Gaps = 5/163 (3%)
 Frame = +1

Query: 16  KSALTIQLIQNHFVDEYDPTIEDSYR-KQVVIDGETCLLDILDTAGQEEY-SAMRDQYMR 73
           K+ LT +     F D+ + TI   +R K + +D E   L + DTAGQE +  +M   Y R
Sbjct: 532 KTCLTYRFCLGKFPDKTEATIGVDFREKSIQVDSEHLKLQLWDTAGQERFRKSMVQHYYR 711

Query: 74  TGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLVGNKCDLAAR-TVESRQAQD 132
                + V+ +    SFE++  + E+  R   +  +P +LVGNKCD+  R  V +  AQ 
Sbjct: 712 NVHAVVFVYDMTKMSSFENMPAWIEECDRHNLTKYIPRILVGNKCDVVERIAVNTNLAQK 891

Query: 133 LARSYGIPYIETSAKTRQGVE--DAFYTLVREIRQHKLRKLNP 173
            A ++ +P  ETSAK  +     DA +  V     HKL+   P
Sbjct: 892 FADAHNMPLFETSAKDDEKANHVDAIFMTV----AHKLKXSKP 1008
>33374
          Length = 489

 Score = 68.9 bits (167), Expect = 1e-12,   Method: Compositional matrix adjust.
 Identities = 40/112 (35%), Positives = 61/112 (54%), Gaps = 1/112 (0%)
 Frame = +1

Query: 44  VVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRV 103
           V +D  T   +I DTAGQE Y ++   Y R  +  + V+ I N  +F     + ++++R 
Sbjct: 154 VCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNQDTFGRAKTWVKELQR- 330

Query: 104 KDSDDVPMVLVGNKCDLA-ARTVESRQAQDLARSYGIPYIETSAKTRQGVED 154
           + S ++ + L GNK DLA  R VE  +AQ  A    + ++ETSAKT   V D
Sbjct: 331 QASPNIVIALAGNKADLANKRMVEFEEAQAYAEENSLLFMETSAKTAMNVND 486
>11728
          Length = 635

 Score = 66.6 bits (161), Expect = 6e-12,   Method: Compositional matrix adjust.
 Identities = 47/152 (30%), Positives = 76/152 (50%), Gaps = 15/152 (9%)
 Frame = -1

Query: 16  KSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTG 75
           K+ L I    N F  EY PT+ D+Y   V++D +   L + DTAGQE+Y  +R       
Sbjct: 452 KTCLLISYTTNAFPGEYIPTVFDNYSANVMVDSKPINLGLWDTAGQEDYDRLRPLSYPQT 273

Query: 76  EGFLCVFAINNTKSFEDIH-QYREQIKRVKDSDDVPMVLVGNKCDLA--ARTVESRQ--- 129
           + FL  F++ +  SFE++  ++  ++       + P++LVG K DL     T+E  +   
Sbjct: 272 DVFLICFSLISPASFENVKAKWYPEVSH--HCPNTPIILVGTKLDLREDKETIEKLKEKK 99

Query: 130 ------AQDLARSYGI---PYIETSAKTRQGV 152
                  Q LA +  I    Y+E SA T++G+
Sbjct: 98  LAPITYPQGLAMAKDIGAGKYLECSALTQKGL 3
>01972
          Length = 2359

 Score = 63.5 bits (153), Expect = 5e-11,   Method: Compositional matrix adjust.
 Identities = 32/111 (28%), Positives = 62/111 (55%)
 Frame = +3

Query: 53  LDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMV 112
            ++ DTAGQE++  +RD Y   G+  + +F + +  +++++  +   + RV   +++P+V
Sbjct: 453 FNVWDTAGQEKFGGLRDGYYIQGQCAVIMFDVTSRVTYKNVPNWHRDLVRV--CENIPIV 626

Query: 113 LVGNKCDLAARTVESRQAQDLARSYGIPYIETSAKTRQGVEDAFYTLVREI 163
           L GNK D+  R V+++ A    R   + Y + SAK+    E  F  L R++
Sbjct: 627 LCGNKVDIKDRKVKAK-AIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKL 776
>30760
          Length = 596

 Score = 63.5 bits (153), Expect = 5e-11,   Method: Compositional matrix adjust.
 Identities = 37/117 (31%), Positives = 62/117 (52%), Gaps = 1/117 (0%)
 Frame = -1

Query: 53  LDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMV 112
           L + D+AG+E +S    ++       + V+ + +  SF    ++ E+++  K +  +P V
Sbjct: 365 LYLFDSAGKEIFSENVTKFWDQPSVVMVVYDVTDETSFSGCVRWLERVRAAKPNTVIPGV 186

Query: 113 LVGNKCDL-AARTVESRQAQDLARSYGIPYIETSAKTRQGVEDAFYTLVREIRQHKL 168
           LV NK DL   R V  ++ +DLA+S+G+ Y E SAK  Q  +  F+ L      HKL
Sbjct: 185 LVANKTDLDERRRVSRKEGKDLAQSHGLEYFECSAKEMQNTDTPFFCLAHAF--HKL 21
>07465
          Length = 1103

 Score = 63.2 bits (152), Expect = 7e-11,   Method: Compositional matrix adjust.
 Identities = 40/134 (29%), Positives = 69/134 (51%), Gaps = 2/134 (1%)
 Frame = +3

Query: 28  FVDEYDPTIE-DSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINN 86
           F  +Y  TI  D   +Q+ + GE   L + DTAGQEE+ A+   Y R  +  +  F+  +
Sbjct: 273 FTKDYKKTIGVDFLERQIEVGGEDVRLMLWDTAGQEEFDAITKAYYRGAQACVLAFSTVD 452

Query: 87  TKSFEDIHQYREQIKRVKDSDDVPMVLVGNKCDLA-ARTVESRQAQDLARSYGIPYIETS 145
             SFE +  ++ +++   +  ++ MV+V NK DL     V   +A++LA+   + +  TS
Sbjct: 453 RDSFEALETWKRKVE--DEVGEIGMVIVQNKIDLIDDAVVRPEEAENLAKKLRLRFYRTS 626

Query: 146 AKTRQGVEDAFYTL 159
            K    V++ F  L
Sbjct: 627 VKENMNVDEVFRYL 668
>19656
          Length = 428

 Score = 60.5 bits (145), Expect = 4e-10,   Method: Compositional matrix adjust.
 Identities = 30/78 (38%), Positives = 43/78 (55%)
 Frame = +3

Query: 16  KSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTG 75
           K+ L I    N F  EY PT+ D+Y   V++DG    L + DTAGQE+Y  +R       
Sbjct: 150 KTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGRPVNLGLWDTAGQEDYDRLRPLSYPQT 329

Query: 76  EGFLCVFAINNTKSFEDI 93
           + FL  F++ +  SFE+I
Sbjct: 330 DVFLLCFSVASPASFENI 383
>01398
          Length = 1421

 Score = 60.1 bits (144), Expect = 5e-10,   Method: Compositional matrix adjust.
 Identities = 30/107 (28%), Positives = 57/107 (53%), Gaps = 1/107 (0%)
 Frame = -2

Query: 61   QEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLVGNKCDL 120
            QE + ++   Y R   G + V+ I    +FE++ Q+ E+ +   +      +++G+K D 
Sbjct: 1420 QERFRSITRSYYRNSVGVIIVYDITKRSTFENLKQWYEEARNHIEPHKAIFLVLGHKSDR 1241

Query: 121  A-ARTVESRQAQDLARSYGIPYIETSAKTRQGVEDAFYTLVREIRQH 166
              AR V +R+ +  A  +G+ + ETSAK+   +ED F  + ++  QH
Sbjct: 1240 EDARQVTAREGRRFAEMHGLKFFETSAKSGHNIEDVFAQIAKDTYQH 1100
>33794
          Length = 779

 Score = 58.9 bits (141), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 34/119 (28%), Positives = 63/119 (52%), Gaps = 1/119 (0%)
 Frame = -1

Query: 44  VVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRV 103
           ++++G+   L I DT+GQ  +  +   Y R  +G + V+ I N  SF+ I ++ ++++  
Sbjct: 671 ILLEGKRVKLQIWDTSGQGRFCTIIRSYSRGAQGIILVYDITNKWSFDGIDRWLKEVE-- 498

Query: 104 KDSDDVPMVLVGNKCDLA-ARTVESRQAQDLARSYGIPYIETSAKTRQGVEDAFYTLVR 161
           + +  +P VLVGN+  LA  R V ++QA+  A    +   E S      + ++F  L R
Sbjct: 497 EHAPGIPKVLVGNRLHLAYKRQVAAKQAETYASRNNMSCFEISPLCDFNIRESFCELAR 321
>13745
          Length = 1045

 Score = 58.9 bits (141), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 34/105 (32%), Positives = 57/105 (54%), Gaps = 4/105 (3%)
 Frame = +2

Query: 61  QEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQI---KRVKDSDDVPMVLVGNK 117
           QE + ++   + R  +  + V+ +    SF+++  +R++       +D +  P V++GNK
Sbjct: 2   QERFQSLGVAFYRGADCCVLVYDVTAPNSFKNLDSWRDEFLIQASPRDPEHFPFVVLGNK 181

Query: 118 CDLAARTVESRQAQDLARSYG-IPYIETSAKTRQGVEDAFYTLVR 161
            DL  R V +R+AQ   +S   IPY ETSAK    VE AF T+ +
Sbjct: 182 VDLDNRQVSTRRAQQWCQSKNDIPYYETSAKEGINVEMAFQTIAK 316
>33380
          Length = 282

 Score = 58.5 bits (140), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 29/68 (42%), Positives = 39/68 (57%)
 Frame = +3

Query: 53  LDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMV 112
           L I DTAGQE Y  +   Y R   GF+ ++ + N +SF  +  +  QIK     D+  +V
Sbjct: 66  LQIWDTAGQERYRTITTAYYRGAMGFILMYDVTNEESFNAVQDWCTQIK-TYSWDNAQVV 242

Query: 113 LVGNKCDL 120
           LVGNKCDL
Sbjct: 243 LVGNKCDL 266
>17511
          Length = 483

 Score = 58.2 bits (139), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 31/109 (28%), Positives = 57/109 (52%), Gaps = 4/109 (3%)
 Frame = -3

Query: 16  KSALTIQLIQNHFVDEYDPTI-EDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRT 74
           K++L  Q +   F ++Y  TI  D   K+V++D     + I DTAGQE + ++   + R 
Sbjct: 328 KTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQIWDTAGQERFQSLGVAFYRG 149

Query: 75  GEGFLCVFAINNTKSFEDIHQYREQI---KRVKDSDDVPMVLVGNKCDL 120
            +  + VF +    +F  +  +R++       +D ++ P V++GNK DL
Sbjct: 148 ADCCVLVFDVTMPNTFRSLDSWRDEFLIQASPRDPENFPFVVIGNKIDL 2
>19006
          Length = 568

 Score = 57.4 bits (137), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 33/106 (31%), Positives = 59/106 (55%), Gaps = 1/106 (0%)
 Frame = -2

Query: 16  KSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTG 75
           K+ L I   ++ F + Y PT+ ++Y   + +D +   L + DTAGQE+Y  +R       
Sbjct: 399 KTCLLIVFSKDQFPEVYVPTVFENYVADIEVDSKQVELALWDTAGQEDYDRLRPLSYPDT 220

Query: 76  EGFLCVFAINNTKSFEDI-HQYREQIKRVKDSDDVPMVLVGNKCDL 120
           +  L  F+I++  S E+I  ++  +++      +VP++LVGNK DL
Sbjct: 219 DVILMCFSIDSPDSLENIPEKWTPEVRHF--CPNVPIILVGNKKDL 88
>12339
          Length = 578

 Score = 57.4 bits (137), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 33/105 (31%), Positives = 57/105 (54%), Gaps = 4/105 (3%)
 Frame = -2

Query: 61  QEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQY-REQIKRV--KDSDDVPMVLVGNK 117
           QE + ++   + R  +  + V+ +   K+F+ +  + RE + +   +D +  P V++GNK
Sbjct: 577 QERFQSLGVAFYRGADCCILVYDVTEXKTFDSLDSWQREFLNQASPRDPEHFPFVVIGNK 398

Query: 118 CDLAARTVESRQAQDLARSYG-IPYIETSAKTRQGVEDAFYTLVR 161
            DL  R V +++ Q    + G IPY ETSAK    VE AF T+ +
Sbjct: 397 IDLDNRVVTAKRGQGWCSTKGGIPYFETSAKEAINVEQAFQTVAK 263
>29380
          Length = 853

 Score = 54.7 bits (130), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 34/115 (29%), Positives = 59/115 (51%), Gaps = 7/115 (6%)
 Frame = -2

Query: 79  LCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLVGNKCDLAA--RTVESRQAQDLARS 136
           + V+ +N   +F     + +++++ ++++ V ++L GNK DLA   R V    AQ  AR 
Sbjct: 840 IIVYDVNIADTFSRALAWVKELRQ-QNTESVLIILAGNKVDLATQHRAVSFEDAQSFARE 664

Query: 137 YGIPYIETSAKTRQGVEDAFYTLVREIRQHKL-----RKLNPPDESGPGCMSCKC 186
            G+ + E SAKT   V + F TL  ++ Q ++     R +    E+G     CKC
Sbjct: 663 NGLLFAEVSAKTGMAVNEIFMTLANQLIQQEIDGSRNRGVTLNRENGEAS-GCKC 502
>34359
          Length = 1042

 Score = 54.3 bits (129), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 26/111 (23%), Positives = 61/111 (54%), Gaps = 6/111 (5%)
 Frame = +3

Query: 53  LDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMV 112
            ++ DTAGQE++  +RD Y   G   + +F + +  +++++  +   + RV   +++P+V
Sbjct: 201 FNVWDTAGQEKFGGLRDGYYIQGTCAIIMFDVTSRVTYKNVPNWHRDLVRV--CENIPIV 374

Query: 113 LVGNKCDLAARTVESR-----QAQDLARSYGIPYIETSAKTRQ-GVEDAFY 157
           L GNK D+  R V+++     + +  + +  +P   T+ ++R  G   +++
Sbjct: 375 LCGNKVDIKDRKVKAKAIVFHRKRTCSTTTSVPRATTTLRSRSCGWRASWW 527
>26083
          Length = 432

 Score = 52.8 bits (125), Expect = 8e-08,   Method: Compositional matrix adjust.
 Identities = 33/118 (27%), Positives = 59/118 (50%), Gaps = 1/118 (0%)
 Frame = +1

Query: 1   MTEYKLXXXXXXXXXKSALTIQLIQNHFVDEYDPTIE-DSYRKQVVIDGETCLLDILDTA 59
           + ++KL         K++L  + + + F + Y  TI  D   K + ++  T  L + DTA
Sbjct: 70  LRKFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTIRLQLWDTA 249

Query: 60  GQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLVGNK 117
           GQE + ++   Y+R     + V+ I N  SF    ++ + + R +   DV ++LVGNK
Sbjct: 250 GQERFRSLIPSYIRDSSVAVVVYDITNANSFHQTSKWIDDV-RTERGSDVIIMLVGNK 420
>34597
          Length = 773

 Score = 51.6 bits (122), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 29/85 (34%), Positives = 47/85 (55%), Gaps = 1/85 (1%)
 Frame = -2

Query: 80  CVFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLVGNKCDLA-ARTVESRQAQDLARSYG 138
           C+      KSFE+I ++   I     ++DV  +++GNKCD+   R V   + + +AR + 
Sbjct: 736 CLMT*RMKKSFENIVKWLRNIDE-HANEDVEKMILGNKCDMTDKRVVSKERGEAIAREHS 560

Query: 139 IPYIETSAKTRQGVEDAFYTLVREI 163
           I ++ETSAK+   +E AF  L   I
Sbjct: 559 IRFMETSAKSNINIERAFCELAEAI 485
>31291
          Length = 446

 Score = 50.8 bits (120), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 39/124 (31%), Positives = 62/124 (50%), Gaps = 15/124 (12%)
 Frame = -1

Query: 53  LDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIH-QYREQIKRVKDSDDVPM 111
           L + DTAGQE+Y  +R       + F+  F++ +  S +++  ++  +I+       VP+
Sbjct: 446 LQLWDTAGQEDYDRLRPLAYPNTDVFMLXFSLMSEASMKNVKVKWYPEIRH--HDPHVPI 273

Query: 112 VLVGNKCDL-----AAR--------TVESRQAQDLARSYGIP-YIETSAKTRQGVEDAFY 157
           VLVG K DL     A R         V S Q  DLA++     Y E S+KT++ ++ AF 
Sbjct: 272 VLVGTKLDLRQDKEAVRKLRSSRQDPVSSNQGNDLAKAIKAKRYFECSSKTQENLKTAFE 93

Query: 158 TLVR 161
             VR
Sbjct: 92  ETVR 81
>10708
          Length = 2775

 Score = 39.3 bits (90), Expect(2) = 4e-07,   Method: Compositional matrix adjust.
 Identities = 27/79 (34%), Positives = 37/79 (46%), Gaps = 16/79 (20%)
 Frame = -3

Query: 108  DVPMVLVGNKCDL----------------AARTVESRQAQDLARSYGIPYIETSAKTRQG 151
            +VP++LVGNK DL                  R  E R   +   +Y   Y+E SAKT++G
Sbjct: 2554 NVPIILVGNKKDLRNDENTKRELMKMKQEPVRLDEGRAMSEKINAYS--YLECSAKTKEG 2381

Query: 152  VEDAFYTLVREIRQHKLRK 170
            V + F T  R   Q K +K
Sbjct: 2380 VREVFETATRAALQTKKKK 2324

 Score = 30.8 bits (68), Expect(2) = 4e-07,   Method: Compositional matrix adjust.
 Identities = 15/43 (34%), Positives = 24/43 (55%)
 Frame = -2

Query: 53   LDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQ 95
            L + DTAGQE+Y  +R       +  L  F+I++  S E+I +
Sbjct: 2717 LALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPE 2589
>01095
          Length = 1745

 Score = 50.4 bits (119), Expect = 4e-07,   Method: Compositional matrix adjust.
 Identities = 32/101 (31%), Positives = 52/101 (51%), Gaps = 1/101 (0%)
 Frame = -1

Query: 81   VFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLVGNKCDLA-ARTVESRQAQDLARSYGI 139
            V+ I N  +F     + ++++R + S ++ + L GNK DLA  R VE  +AQ  A    +
Sbjct: 1742 VYDITNQDTFGRAKTWVKELQR-QASPNIVIALAGNKADLANKRMVEFEEAQAYAEENSL 1566

Query: 140  PYIETSAKTRQGVEDAFYTLVREIRQHKLRKLNPPDESGPG 180
             ++ETSAKT   V D F  + +++         P +E G G
Sbjct: 1565 LFMETSAKTAMNVNDIFLAIAKKL---------PKNEGGGG 1470
>25655
          Length = 871

 Score = 34.3 bits (77), Expect(2) = 1e-05,   Method: Compositional matrix adjust.
 Identities = 14/21 (66%), Positives = 17/21 (80%)
 Frame = -3

Query: 131 QDLARSYGIPYIETSAKTRQG 151
           + +A  Y IPY+ETSAKTRQG
Sbjct: 869 KHMAELYHIPYVETSAKTRQG 807

 Score = 31.2 bits (69), Expect(2) = 1e-05,   Method: Compositional matrix adjust.
 Identities = 13/16 (81%), Positives = 16/16 (100%)
 Frame = -2

Query: 152 VEDAFYTLVREIRQHK 167
           V+DAFYTLVREIR++K
Sbjct: 807 VDDAFYTLVREIRKYK 760
>14119
          Length = 602

 Score = 45.1 bits (105), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 30/84 (35%), Positives = 42/84 (50%), Gaps = 2/84 (2%)
 Frame = +1

Query: 102 RVKDSDDVPMVLVGNKCDLAA--RTVESRQAQDLARSYGIPYIETSAKTRQGVEDAFYTL 159
           R +++  V +VL GNK DLA+  R V +  A+  A   G+ + E SAKT   V + F T+
Sbjct: 37  RQQNAGSVLIVLAGNKADLASEHRAVSADDARTFAEDNGLIFAEVSAKTGMAVSEVFMTI 216

Query: 160 VREIRQHKLRKLNPPDESGPGCMS 183
                 HKL +     E G G  S
Sbjct: 217 A-----HKLVR---RAEEGGGVWS 264
>25618
          Length = 475

 Score = 44.7 bits (104), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 31/98 (31%), Positives = 49/98 (50%), Gaps = 13/98 (13%)
 Frame = +3

Query: 102 RVKDSDDVPMVLVGNKCDLAA--RTVESRQAQDLARSYGIPYIETSAKTRQGVEDAFYTL 159
           R +++  V +VL GNK DLA+  R V +  A+  A   G+ + E SAKT   V + F T+
Sbjct: 57  RQQNAGSVLIVLAGNKADLASEHRAVSADDARTFAEDNGLIFAEVSAKTGMAVSEVFMTI 236

Query: 160 VREI----------RQHKLR-KLNPPDESGPGCMSCKC 186
             ++           Q + R +L+  +E+  G   CKC
Sbjct: 237 AHKLVRRAEEGQGSXQGRERVRLSEAEEASGG---CKC 341
>00552
          Length = 455

 Score = 37.4 bits (85), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 15/46 (32%), Positives = 27/46 (58%)
 Frame = -3

Query: 55  ILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQI 100
           I DTAGQE Y ++R  + R  +  L  F+++N KS + +  + ++ 
Sbjct: 147 IWDTAGQERYKSLRTPFYRGTDCCLLTFSVDNLKSLQSLSDWYDEF 10
>31928
          Length = 429

 Score = 35.8 bits (81), Expect = 0.011,   Method: Compositional matrix adjust.
 Identities = 24/87 (27%), Positives = 43/87 (49%), Gaps = 4/87 (4%)
 Frame = +2

Query: 35  TIEDSYRKQVVID-GETCLLDILDTAGQEEYSAMRD---QYMRTGEGFLCVFAINNTKSF 90
           TIED Y   +  D G    + I DT      +   D    Y+   +GF+ V+   + +SF
Sbjct: 53  TIEDIYTAVIETDRGVKEKVRIFDTGAAALETTEGDLPKHYLNFPDGFVLVYDTTSWESF 232

Query: 91  EDIHQYREQIKRVKDSDDVPMVLVGNK 117
             + + ++ I + +D  +V M+++GNK
Sbjct: 233 RRLDKLKKDIDKHRDKREVHMIVIGNK 313
>21396
          Length = 647

 Score = 32.3 bits (72), Expect = 0.13,   Method: Compositional matrix adjust.
 Identities = 15/42 (35%), Positives = 21/42 (50%)
 Frame = -2

Query: 28  FVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRD 69
           F +E  PT       Q +  G  CLL +L T+  E +S +RD
Sbjct: 388 FFEELRPTTSHHDHTQSLFHGRLCLLFLLCTSALEIHSFLRD 263
>35581
          Length = 364

 Score = 30.4 bits (67), Expect = 0.48,   Method: Compositional matrix adjust.
 Identities = 13/38 (34%), Positives = 20/38 (52%)
 Frame = +2

Query: 45  VIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVF 82
           +  G    +D+ DTAGQE Y ++   Y R  +  L V+
Sbjct: 176 LTSGVMASVDLWDTAGQERYRSLTSSYYRDTKAVLIVY 289
>33373
          Length = 420

 Score = 27.3 bits (59), Expect = 3.6,   Method: Compositional matrix adjust.
 Identities = 12/28 (42%), Positives = 18/28 (64%)
 Frame = -3

Query: 70  QYMRTGEGFLCVFAINNTKSFEDIHQYR 97
           QY++TGE +L  + +NN+    DI QY 
Sbjct: 259 QYLKTGEQWLH*WYLNNSS*TRDIAQYN 176
>30463
          Length = 412

 Score = 26.6 bits (57), Expect = 5.8,   Method: Compositional matrix adjust.
 Identities = 14/26 (53%), Positives = 14/26 (53%)
 Frame = -1

Query: 113 LVGNKCDLAARTVESRQAQDLARSYG 138
           LV NK  L A    SR A DLA  YG
Sbjct: 232 LVANKASLTAEDAFSRTAYDLADQYG 155
>18949
          Length = 414

 Score = 26.2 bits (56), Expect = 8.3,   Method: Compositional matrix adjust.
 Identities = 12/64 (18%), Positives = 29/64 (45%)
 Frame = +3

Query: 56  LDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLVG 115
            D  G  +   +   Y    +G + +  +++T+   +     + + R     D+P++++G
Sbjct: 72  FDLGGHRQARRVWKDYFPAVDGIVFIVDVHDTERITEAKAELDSLLRDDQIADIPVLVLG 251

Query: 116 NKCD 119
           NK D
Sbjct: 252 NKMD 263
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|154146249|ref|NP_083174.2| raptor [Mus musculus]
         (1335 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

38976                                                                 262   8e-70
32189                                                                  33   1.0  
09905                                                                  32   2.0  
02960                                                                  32   2.0  
26107                                                                  31   2.9  
02147                                                                  31   3.4  
10162                                                                  31   3.7  
21960                                                                  30   4.4  
>38976
          Length = 459

 Score =  262 bits (669), Expect = 8e-70,   Method: Compositional matrix adjust.
 Identities = 116/137 (84%), Positives = 131/137 (95%)
 Frame = -1

Query: 46  AQSWRMKDRMKTVSVALVLCLNVGVDPPDVVKTTPCARLECWIDPLSMGPQKALETIGAN 105
            Q+WRMK+RMKTVSVALVLCLNVGVDPPD++K +PCA+++CWIDP+++  QKALETIG N
Sbjct: 411 TQTWRMKERMKTVSVALVLCLNVGVDPPDIIKISPCAKMQCWIDPVTVSAQKALETIGGN 232

Query: 106 LQKQYENWQPRARYKQSLDPTVDEVKKLCTSLRRNAKEERVLFHYNGHGVPRPTVNGEVW 165
           LQKQYE WQPRARYKQSLDPTVDEVKKLCTSLRRNAKEERVLFHY+GHGVPRPTVNGE+W
Sbjct: 231 LQKQYERWQPRARYKQSLDPTVDEVKKLCTSLRRNAKEERVLFHYSGHGVPRPTVNGEIW 52

Query: 166 VFNKNYTQYIPLSIYDL 182
           VFNK+YTQYIPLS+YDL
Sbjct: 51  VFNKSYTQYIPLSLYDL 1
>32189
          Length = 1688

 Score = 32.7 bits (73), Expect = 1.0,   Method: Compositional matrix adjust.
 Identities = 26/99 (26%), Positives = 45/99 (45%), Gaps = 6/99 (6%)
 Frame = +1

Query: 965  RYFAQPVMKIPEEHDLESQIRKEREWRFLRNTRVRKQAQQV-IQKGITRLDDQIFLNRNP 1023
            R+ + PV+    +H   S ++++R+      T+ RK   ++ IQK   +      + R P
Sbjct: 1279 RFLSVPVLTSCTQHMRTSGLKRQRK------TKTRKPCSELRIQKR*LKTTLASLIARGP 1440

Query: 1024 GV---PS--VVKFHPFTPCIAVADKDSICFWDWEKGEKL 1057
                 PS  +    P T C  V    S CFW W++G ++
Sbjct: 1441 KTHVTPSRNITVKAPRT-CAGVTPSASFCFWCWKRGLRI 1554
>09905
          Length = 1980

 Score = 31.6 bits (70), Expect = 2.0,   Method: Composition-based stats.
 Identities = 18/50 (36%), Positives = 29/50 (58%), Gaps = 1/50 (2%)
 Frame = +2

Query: 139  RNAKEERVLFHYNGHGVPRPTVNGEVWVFNKNY-TQYIPLSIYDLQTWMG 187
            +NA  + VL  YN   +    + G   + N+NY T+ +PL IY L++W+G
Sbjct: 1826 KNAYFKNVLLKYNS--IYGKLMYGTFTLINRNYLTKPVPLLIYYLKSWIG 1969
>02960
          Length = 1577

 Score = 31.6 bits (70), Expect = 2.0,   Method: Compositional matrix adjust.
 Identities = 16/68 (23%), Positives = 30/68 (44%)
 Frame = +2

Query: 1180 LIVAGLGDGSIRVYDRRMALSECRVMTYREHTAWVVKAYLQKHPEGHIVSVSVNGDVRFF 1239
            +++ G  D  +R+ D R +  E     +  HT WV         E   +S S +  ++ +
Sbjct: 1121 MLITGSADRHVRLVDPRCSEGETVKCAFTSHTGWVTGVDWSPTREHLFLSGSYDNVLKLW 1300

Query: 1240 DPRMPESV 1247
            D R P++ 
Sbjct: 1301 DTRSPKAT 1324
>26107
          Length = 1338

 Score = 31.2 bits (69), Expect = 2.9,   Method: Compositional matrix adjust.
 Identities = 20/64 (31%), Positives = 32/64 (50%)
 Frame = -3

Query: 1134 ETGLLMSSGDVRIVRIWDTDRETKVQDIPTGADSCVTSLSCDSHRSLIVAGLGDGSIRVY 1193
            ++  L +SGD + V +WD +  TKV        S  +  SC S  +   +G  DG I ++
Sbjct: 1051 DSQCLTASGD-QTVALWDVETTTKVTTFIGHKCSVRSVASCPSSPAQCASGARDGHIMLW 875

Query: 1194 DRRM 1197
            D R+
Sbjct: 874  DSRV 863
>02147
          Length = 1547

 Score = 30.8 bits (68), Expect = 3.4,   Method: Compositional matrix adjust.
 Identities = 31/138 (22%), Positives = 67/138 (48%)
 Frame = +2

Query: 1045 SICFWDWEKGEKLDYFHNGNPRYTRVTAMEYLNGQDCSLLLTATDDGAIRVWKNFADLEK 1104
            S   WD EKGE+L  F + +     V ++++    D + LLT +++  ++V+ +  + + 
Sbjct: 242  SAKIWDAEKGEELQTFSHKHI----VKSVDF--SHDGTALLTGSNEKLLKVF-DLVNTDA 400

Query: 1105 NPEMVTAWQGLSDMLPTTRGAGMVVDWEQETGLLMSSGDVRIVRIWDTDRETKVQDIPTG 1164
             P      +  +      +GA  + D ++    ++S+ D + VR+W  +   +VQ +   
Sbjct: 401  EP------KSFAGHTSNIKGALFLSDGKR----IISASDDKTVRLWSLETCQEVQQLT-- 544

Query: 1165 ADSCVTSLSCDSHRSLIV 1182
             D+  TSL+    ++ I+
Sbjct: 545  FDTPPTSLTLSPDKNTII 598
>10162
          Length = 1629

 Score = 30.8 bits (68), Expect = 3.7,   Method: Compositional matrix adjust.
 Identities = 28/113 (24%), Positives = 48/113 (42%), Gaps = 6/113 (5%)
 Frame = +3

Query: 1086 TATDDGAIRVWKNFADLEK----NPEMVTAWQGLSDMLPTTRGAGMVVDWEQETGLLMSS 1141
            TAT+ G+++VW     + +    +PE V   Q                 W   T LL ++
Sbjct: 570  TATNSGSVQVWDLPTSVARHSFQHPEGVCKLQ-----------------WSSSTALLYTA 698

Query: 1142 GDVRIVRIWDTDRETKVQDIPTGA--DSCVTSLSCDSHRSLIVAGLGDGSIRV 1192
                ++R+WD  R    + + TG   +SC+         + +V+G  DG+ RV
Sbjct: 699  CLDGVMRVWDA-RSGASKAVLTGHARNSCILDFDVTRDGTCLVSGSEDGTARV 854
>21960
          Length = 756

 Score = 30.4 bits (67), Expect = 4.4,   Method: Compositional matrix adjust.
 Identities = 17/67 (25%), Positives = 29/67 (43%)
 Frame = +1

Query: 1263 PQANLIACGSMNQFTAIYNGNGELINNIKYYDGFMGQRVGAISCLAFHPHWPHLAVGSND 1322
            P +  I  GS +     ++ N E + N        G   G ++CL  HP  P LA    D
Sbjct: 394  PHSEHIISGSDDGNIFYWDKNTEAVTNF-----MKGDDAGVVNCLEQHPTMPVLATSGLD 558

Query: 1323 YYISVYS 1329
            + + +++
Sbjct: 559  HNVKIWT 579
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|18079341|ref|NP_542366.1| eukaryotic translation
initiation factor 3, subunit H [Mus musculus]
         (352 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

09316                                                                 259   1e-69
01108                                                                 223   1e-58
37064                                                                 128   3e-45
23227                                                                  87   9e-18
25605                                                                  80   1e-15
>09316
          Length = 2312

 Score =  259 bits (663), Expect = 1e-69,   Method: Compositional matrix adjust.
 Identities = 130/216 (60%), Positives = 158/216 (73%), Gaps = 1/216 (0%)
 Frame = -3

Query: 34  SAVKQVQIDGLVVLKIIKHYXXXXXXXXXXXXXXXXXXXXD-RLEITNCFPFPQHTEDDA 92
           S V+ VQIDGLV LKIIKH                     D RLEITNCFPFP+H+E+D 
Sbjct: 645 SHVQFVQIDGLVALKIIKHSQEESAGGTDLVQGMLLGLVVDNRLEITNCFPFPRHSEED- 469

Query: 93  DFDEVQYQMEMMRSLRHVNIDHLHVGWYQSTYYGSFVTRALLDSQFSYQHAIEESVVLIY 152
           DFDEV Y MEMMR LRHVNIDHL+VGWYQSTY+GSF+ R LL+SQF YQHAIEESV LIY
Sbjct: 468 DFDEVNYPMEMMRYLRHVNIDHLNVGWYQSTYFGSFINRPLLESQFGYQHAIEESVALIY 289

Query: 153 DPIKTAQGSLSLKAYRLTPKLMEVCKEKDFSPEALKKASITFEHMFEEVPIVIKNSHLIN 212
           DP+KT QG LSLKAYRLTP +M+  KE +F+PEA+ + SI+FE+MFEE+P+V+KNSHL+N
Sbjct: 288 DPLKTTQGFLSLKAYRLTPAMMKFYKEGEFTPEAIAQHSISFENMFEEIPVVLKNSHLVN 109

Query: 213 VLMWELEKKSAVADKHELLSLASSNHLGKSLQLLMD 248
            L+ EL + +    K   L L +S  L K+L+ LM+
Sbjct: 108 ALLCELSETTKRDHKFNFLDLGTSAVLEKNLRQLME 1
>01108
          Length = 860

 Score =  223 bits (567), Expect = 1e-58,   Method: Compositional matrix adjust.
 Identities = 112/218 (51%), Positives = 149/218 (68%)
 Frame = +3

Query: 132 ALLDSQFSYQHAIEESVVLIYDPIKTAQGSLSLKAYRLTPKLMEVCKEKDFSPEALKKAS 191
           +LL+SQF YQHAIEESV LIYDP+KT QG LSLKAYRLTP +M+  KE +F+PEA+ + S
Sbjct: 33  SLLESQFGYQHAIEESVALIYDPLKTTQGFLSLKAYRLTPAMMKFYKEGEFTPEAIAQHS 212

Query: 192 ITFEHMFEEVPIVIKNSHLINVLMWELEKKSAVADKHELLSLASSNHLGKSLQLLMDRVD 251
           I+FE+MFEE+P+V+KNSHL+N L+ EL + +    K   L L +S  L K+L+ LM+ VD
Sbjct: 213 ISFENMFEEIPVVLKNSHLVNALLCELSETTKRDHKFNFLDLGTSAVLEKNLRQLMESVD 392

Query: 252 EMSQDIIKYNTYMRNTSKXXXXXXXXXXXXXXXXXXXXXXGEPPLPEEDLSKLFKPHQAP 311
           E++ D  KY  + R   +                      GEPPLPEED++KLFKP Q P
Sbjct: 393 EVAMDTNKYLNFQRQNFRQQQAKQQHLQKRQQENQQRVVRGEPPLPEEDINKLFKPLQPP 572

Query: 312 ARMDSLLIAGQINTYCQNIKEFTAQNLGKLFMAQALQE 349
            R+D LL+A QI+ YC +I EF+AQ++ KL MA++LQE
Sbjct: 573 PRLDCLLVANQIDQYCNSISEFSAQSIAKLLMAESLQE 686
>37064
          Length = 715

 Score =  128 bits (322), Expect(3) = 3e-45,   Method: Compositional matrix adjust.
 Identities = 61/138 (44%), Positives = 97/138 (70%)
 Frame = -2

Query: 126 GSFVTRALLDSQFSYQHAIEESVVLIYDPIKTAQGSLSLKAYRLTPKLMEVCKEKDFSPE 185
           G+ ++ ALL+SQ+ YQ +IEESVV++YD  K+++G L LKAYRLTP+ +++ K+ DF+PE
Sbjct: 591 GNSLSLALLESQYHYQTSIEESVVVVYDTQKSSRGFLCLKAYRLTPQAIQMYKDGDFTPE 412

Query: 186 ALKKASITFEHMFEEVPIVIKNSHLINVLMWELEKKSAVADKHELLSLASSNHLGKSLQL 245
           A +   + +E +F E+PIVIKNS L N++M EL +       H  L L +++ L   ++ 
Sbjct: 411 AFRTLKVGYESLFAEIPIVIKNSPLTNIMMSELNELLPEDKGHNFLDLGTASVLENHMRS 232

Query: 246 LMDRVDEMSQDIIKYNTY 263
           L++RVDE+ Q+ ++YN Y
Sbjct: 231 LIERVDELYQEAVRYNKY 178

 Score = 52.0 bits (123), Expect(3) = 3e-45,   Method: Compositional matrix adjust.
 Identities = 22/41 (53%), Positives = 27/41 (65%)
 Frame = -3

Query: 91  DADFDEVQYQMEMMRSLRHVNIDHLHVGWYQSTYYGSFVTR 131
           D   DE  YQ+ +MR LR VN+DHLHVGWYQS+   +   R
Sbjct: 698 DETMDEEMYQLTVMRRLRRVNVDHLHVGWYQSSDCWAIACR 576

 Score = 39.7 bits (91), Expect(3) = 3e-45,   Method: Compositional matrix adjust.
 Identities = 15/30 (50%), Positives = 23/30 (76%)
 Frame = -3

Query: 292 GEPPLPEEDLSKLFKPHQAPARMDSLLIAG 321
           GEP LPEE++ KL++P Q PAR+ + + +G
Sbjct: 92  GEPTLPEEEVLKLYRPMQVPARLTATITSG 3
>23227
          Length = 1206

 Score = 87.0 bits (214), Expect = 9e-18,   Method: Compositional matrix adjust.
 Identities = 37/58 (63%), Positives = 48/58 (82%)
 Frame = +1

Query: 292  GEPPLPEEDLSKLFKPHQAPARMDSLLIAGQINTYCQNIKEFTAQNLGKLFMAQALQE 349
            GEPPLPEED++KLFKP Q P R+D LL+A QI+ YC +I EF+AQ++ KL MA++LQE
Sbjct: 991  GEPPLPEEDINKLFKPLQPPPRLDCLLVANQIDQYCNSISEFSAQSIAKLLMAESLQE 1164
>25605
          Length = 556

 Score = 80.1 bits (196), Expect = 1e-15,   Method: Compositional matrix adjust.
 Identities = 34/55 (61%), Positives = 45/55 (81%)
 Frame = +1

Query: 295 PLPEEDLSKLFKPHQAPARMDSLLIAGQINTYCQNIKEFTAQNLGKLFMAQALQE 349
           PLPEED++KLFKP Q P R+D LL+A QI+ YC +I EF+AQ++ KL MA++LQE
Sbjct: 217 PLPEEDINKLFKPLQPPPRLDCLLVANQIDQYCNSISEFSAQSIAKLLMAESLQE 381
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6755000|ref|NP_035181.1| programmed cell death 6 [Mus
musculus]
         (191 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

03732                                                                 258   1e-69
27864                                                                 146   5e-36
12214                                                                 107   4e-24
32241                                                                  56   8e-09
14366                                                                  55   2e-08
16109                                                                  53   7e-08
08108                                                                  49   2e-06
14945                                                                  48   2e-06
11425                                                                  48   3e-06
22063                                                                  47   5e-06
01401                                                                  37   0.006
32088                                                                  37   0.006
17484                                                                  36   0.011
32153                                                                  30   0.71 
03845                                                                  29   1.3  
00167                                                                  29   1.4  
18171                                                                  28   1.6  
17810                                                                  28   3.3  
07678                                                                  27   5.5  
02929                                                                  26   10.0 
>03732
          Length = 1114

 Score =  258 bits (658), Expect = 1e-69,   Method: Compositional matrix adjust.
 Identities = 118/167 (70%), Positives = 142/167 (85%)
 Frame = -1

Query: 24   DQSFLWNVFQRVDKDRSGVISDNELQQALSNGTWTPFNPVTVRSIISMFDRENKAGVNFS 83
            D +FL  +FQR+DKDRSG IS NELQQALSNGTWTPFNP TVR +I MFDR+N   +NF 
Sbjct: 1108 DPNFLAGIFQRIDKDRSGNISVNELQQALSNGTWTPFNPETVRLMIGMFDRDNSGTINFQ 929

Query: 84   EFTGVWKYITDWQNVFRTYDRDNSGMIDKNELKQALSGFGYRLSDQFHDILIRKFDRQGR 143
            EF  +WKY+TDWQN FR+YDRDNSG ID+NELK AL+GFGYRLSD+F D+L++KFDRQG+
Sbjct: 928  EFQALWKYVTDWQNCFRSYDRDNSGSIDRNELKNALTGFGYRLSDRFFDVLVKKFDRQGK 749

Query: 144  GQIAFDDFIQGCIVLQRLTDIFRRYDTDQDGWIQVSYEQYLSMVFSI 190
            G +AFDDFIQ C+VLQ LT  FR +D DQDGWIQ+SYEQ+L++VFS+
Sbjct: 748  GTVAFDDFIQCCVVLQTLTTSFRTHDQDQDGWIQISYEQFLTLVFSL 608
>27864
          Length = 343

 Score =  146 bits (369), Expect = 5e-36,   Method: Compositional matrix adjust.
 Identities = 68/100 (68%), Positives = 78/100 (78%)
 Frame = +1

Query: 24  DQSFLWNVFQRVDKDRSGVISDNELQQALSNGTWTPFNPVTVRSIISMFDRENKAGVNFS 83
           D +FL  +FQR+DKDRSG IS NELQQALSNGTWTPFNP TVR +I MFDR+N   +NF 
Sbjct: 7   DPNFLAGIFQRIDKDRSGNISVNELQQALSNGTWTPFNPETVRLMIGMFDRDNSGTINFQ 186

Query: 84  EFTGVWKYITDWQNVFRTYDRDNSGMIDKNELKQALSGFG 123
           EF  +WKY+TDWQN FR+YDRDNSG ID+NELK      G
Sbjct: 187 EFQALWKYVTDWQNCFRSYDRDNSGSIDRNELKMPXPDLG 306
>12214
          Length = 654

 Score =  107 bits (266), Expect = 4e-24,   Method: Compositional matrix adjust.
 Identities = 49/124 (39%), Positives = 77/124 (62%)
 Frame = -3

Query: 64  TVRSIISMFDRENKAGVNFSEFTGVWKYITDWQNVFRTYDRDNSGMIDKNELKQALSGFG 123
           T R +I MFDR+    ++ +EF  +W+YI  W++ F  YD + SG I+ NEL+ A    G
Sbjct: 652 TSRLMIGMFDRDMSGTIDINEFQSLWQYIQQWRSTFERYDSNRSGSIEGNELQAAYQQMG 473

Query: 124 YRLSDQFHDILIRKFDRQGRGQIAFDDFIQGCIVLQRLTDIFRRYDTDQDGWIQVSYEQY 183
           + +S +F   ++ KFD  GR  +  D+FIQ C++L+ LTD FR+ DT   G + ++YE +
Sbjct: 472 FNVSPRFVQTVLYKFDHFGRRSLTLDNFIQSCVMLKSLTDAFRQRDTGSTGVVNMAYEDF 293

Query: 184 LSMV 187
           L+M 
Sbjct: 292 LTMA 281

 Score = 35.8 bits (81), Expect = 0.012,   Method: Compositional matrix adjust.
 Identities = 21/82 (25%), Positives = 39/82 (47%)
 Frame = -3

Query: 30  NVFQRVDKDRSGVISDNELQQALSNGTWTPFNPVTVRSIISMFDRENKAGVNFSEFTGVW 89
           + F+R D +RSG I  NELQ A     +   +P  V++++  FD   +  +    F    
Sbjct: 553 STFERYDSNRSGSIEGNELQAAYQQMGFN-VSPRFVQTVLYKFDHFGRRSLTLDNFIQSC 377

Query: 90  KYITDWQNVFRTYDRDNSGMID 111
             +    + FR  D  ++G+++
Sbjct: 376 VMLKSLTDAFRQRDTGSTGVVN 311
>32241
          Length = 328

 Score = 56.2 bits (134), Expect = 8e-09,   Method: Compositional matrix adjust.
 Identities = 27/71 (38%), Positives = 40/71 (56%)
 Frame = -2

Query: 96  QNVFRTYDRDNSGMIDKNELKQALSGFGYRLSDQFHDILIRKFDRQGRGQIAFDDFIQGC 155
           +  F   D + SG I+ NEL  A    G+ +S QF   ++ KFD   R  ++ D FIQ C
Sbjct: 243 EGTFERIDTNRSGSIEANELVTAYRQMGFNVSPQFVQTVLYKFDHLARRSLSLDMFIQSC 64

Query: 156 IVLQRLTDIFR 166
           ++L+ LTD F+
Sbjct: 63  VMLRSLTDAFK 31

 Score = 28.9 bits (63), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 20/79 (25%), Positives = 36/79 (45%), Gaps = 4/79 (5%)
 Frame = -2

Query: 31  VFQRVDKDRSGVISDNELQQALSNGTWTPFNPVTVRSIISMFDRENKAGVNFSEFTGVWK 90
            F+R+D +RSG I  NEL  A     +   +P  V++++  FD   +  ++   F     
Sbjct: 237 TFERIDTNRSGSIEANELVTAYRQMGFN-VSPQFVQTVLYKFDHLARRSLSLDMFIQSCV 61

Query: 91  YITDWQNVFRT----YDRD 105
            +    + F+     YDR+
Sbjct: 60  MLRSLTDAFKQTRPGYDRN 4
>14366
          Length = 499

 Score = 55.1 bits (131), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 22/60 (36%), Positives = 41/60 (68%)
 Frame = -3

Query: 94  DWQNVFRTYDRDNSGMIDKNELKQALSGFGYRLSDQFHDILIRKFDRQGRGQIAFDDFIQ 153
           + +  FR +D++ +GMI+  EL+  L+  G +LSD+  D +IR+ D  G GQ++++DF++
Sbjct: 248 NLREAFRIFDKEGNGMINAAELRHVLTHLGEKLSDEEVDEMIREADISGDGQVSYNDFVK 69
>16109
          Length = 1490

 Score = 53.1 bits (126), Expect = 7e-08,   Method: Compositional matrix adjust.
 Identities = 34/123 (27%), Positives = 57/123 (46%), Gaps = 1/123 (0%)
 Frame = +3

Query: 64   TVRSIISMFDRENKAGVNFSEFTGVWKYITDWQNVFRTYDRDNSGMIDKNELKQALSGFG 123
            T R ++S+ DR+    ++      +W Y+  W   F T D     ++D  ELK      G
Sbjct: 945  TCRCLLSLLDRDITGRLSLEAVKTIWNYVKVWTKAFHTTDVSKDKLVDTFELKDLFKKIG 1124

Query: 124  YRL-SDQFHDILIRKFDRQGRGQIAFDDFIQGCIVLQRLTDIFRRYDTDQDGWIQVSYEQ 182
            + + S+    I+ R  D  G+  I  DDF+Q    +  L  IF++  +  DG I  +  +
Sbjct: 1125 FTIDSEVLKRIVCRYGDEDGK--IHEDDFLQSFCRVLALYHIFKKKSS--DGLITQNLSE 1292

Query: 183  YLS 185
            +LS
Sbjct: 1293 WLS 1301
>08108
          Length = 818

 Score = 48.5 bits (114), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 31/92 (33%), Positives = 44/92 (47%), Gaps = 6/92 (6%)
 Frame = +2

Query: 94  DWQNVFRTYDRDNSGMIDKNELKQALSGFGYRLSDQFHDILIRKFDRQGRGQIAFDDF-- 151
           + Q  F  +D D SG I   EL +AL   G  ++D     LI+K+D    G I  D+F  
Sbjct: 128 ECQTAFAVFDTDGSGSISAGELGEALRAQGADITDDQTAELIKKYDSDSNGDIDTDEFRK 307

Query: 152 -IQGCIVLQRLTD---IFRRYDTDQDGWIQVS 179
            ++G   + RL     +F+  D D DG I  S
Sbjct: 308 LVEGESDVARLAQSALMFKSLDADGDGQITAS 403
>14945
          Length = 1337

 Score = 48.1 bits (113), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 31/103 (30%), Positives = 50/103 (48%), Gaps = 14/103 (13%)
 Frame = +1

Query: 86  TGVWKYITDWQN-----VFRTYDRDNSGMIDKNELKQALSGFGYRLSDQFHDILIRKFDR 140
           TG    +T+ Q       F  +D D SG ID  ELK A+   G+    +    +I + D+
Sbjct: 76  TGPKCELTEEQKQEIREAFDLFDADGSGTIDAKELKVAMRALGFEPKKEEIKKMIAEIDK 255

Query: 141 QGRGQIAFDDFIQGCIVLQRLTD---------IFRRYDTDQDG 174
           +G G I F+DF+   I+ Q++++          FR +D D+ G
Sbjct: 256 EGTGTIDFNDFL--TIMTQKMSEKDAKEEILKAFRLFDDDETG 378
>11425
          Length = 599

 Score = 47.8 bits (112), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 25/62 (40%), Positives = 36/62 (58%), Gaps = 2/62 (3%)
 Frame = -2

Query: 94  DWQNVFRTYDRDNSGMIDKNELKQALSGFGYRLSDQFHDILIRKFDRQG--RGQIAFDDF 151
           D+   F+T+DR+  G I   EL+  L+G G RLSD   D LI+  D +    G + ++DF
Sbjct: 328 DFMEGFKTFDREGQGFISAAELRHLLTGLGERLSDDEVDELIKATDTREDLEGNVKYEDF 149

Query: 152 IQ 153
           IQ
Sbjct: 148 IQ 143
>22063
          Length = 688

 Score = 47.0 bits (110), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 31/103 (30%), Positives = 50/103 (48%), Gaps = 14/103 (13%)
 Frame = +3

Query: 86  TGVWKYITDWQN-----VFRTYDRDNSGMIDKNELKQALSGFGYRLSDQFHDILIRKFDR 140
           TG    +T+ Q       F  +D D SG ID  ELK A+   G+    +    +I + D+
Sbjct: 135 TGPKCELTEEQKQEIREAFDLFDADGSGTIDAKELKVAMRALGFEPKKEEIKKMIAEIDK 314

Query: 141 QGRGQIAFDDFIQGCIVLQRLTD---------IFRRYDTDQDG 174
           +G G I F+DF+   I+ Q++++          FR +D D+ G
Sbjct: 315 EGTGTIDFNDFL--TIMTQKMSEKDAKEEILKAFRLFDDDETG 437
>01401
          Length = 1454

 Score = 37.0 bits (84), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 21/81 (25%), Positives = 42/81 (51%), Gaps = 4/81 (4%)
 Frame = +1

Query: 47  ELQQALSNGTWTPFNPVTVRSIISMFDRENKAGV-NFSEF---TGVWKYITDWQNVFRTY 102
           EL+ A +       +   ++ +++  D+++K  V ++ EF    G+ +  T   +VFR  
Sbjct: 112 ELEGACNKEMGVAISADRIQQLLTALDKDSKDEVIDYEEFLRVMGMQEAATVMAHVFRQL 291

Query: 103 DRDNSGMIDKNELKQALSGFG 123
           D+DNSG + + E+  A+   G
Sbjct: 292 DKDNSGSLTREEIMAAVQSEG 354
>32088
          Length = 1928

 Score = 36.6 bits (83), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 18/60 (30%), Positives = 31/60 (51%)
 Frame = +1

Query: 92  ITDWQNVFRTYDRDNSGMIDKNELKQALSGFGYRLSDQFHDILIRKFDRQGRGQIAFDDF 151
           +T+ ++VF + D DN+G I   EL  A    G  +       ++ K+D  G G++  D+F
Sbjct: 940 LTELRSVFDSIDDDNNGHISXGELDSAFRAVGLNIPGYELRTIMSKYDASGDGRLNMDEF 1119
>17484
          Length = 471

 Score = 35.8 bits (81), Expect = 0.011,   Method: Compositional matrix adjust.
 Identities = 23/69 (33%), Positives = 37/69 (53%)
 Frame = -3

Query: 28  LWNVFQRVDKDRSGVISDNELQQALSNGTWTPFNPVTVRSIISMFDRENKAGVNFSEFTG 87
           + + F+  D++  GVIS +EL+QA++       +   V SII   D++    VN+ EFT 
Sbjct: 265 MRDAFRAFDQNGDGVISISELRQAMAK-MGQKLSDADVESIIRDVDKDGDGFVNYEEFT- 92

Query: 88  VWKYITDWQ 96
             K+I   Q
Sbjct: 91  --KFIAGQQ 71

 Score = 28.9 bits (63), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 13/47 (27%), Positives = 25/47 (53%)
 Frame = -1

Query: 102 YDRDNSGMIDKNELKQALSGFGYRLSDQFHDILIRKFDRQGRGQIAF 148
           YD+D +G I +NE +  +   G+ LS++  + +++  D    G I  
Sbjct: 465 YDQDGNGKITRNEFRSVVRMLGHSLSEKELEEMMQAADTDASGAIEL 325
>32153
          Length = 471

 Score = 29.6 bits (65), Expect = 0.71,   Method: Compositional matrix adjust.
 Identities = 21/82 (25%), Positives = 37/82 (45%), Gaps = 3/82 (3%)
 Frame = -1

Query: 30  NVFQRVDKDRSGVISDNELQQALSNGTWT---PFNPVTVRSIISMFDRENKAGVNFSEFT 86
           N+F  +D D  G I+ NEL+Q   N       PF  + +R +++  D +    +   E+ 
Sbjct: 414 NMFNAIDADSDGKITFNELKQNYGNKMLKMMEPFLTIMMRMLMNNADGDGDGLITLQEWY 235

Query: 87  GVWKYITDWQNVFRTYDRDNSG 108
            + K    +   F+    D+SG
Sbjct: 234 TLMK--IQY*EAFKNLTVDSSG 175

 Score = 28.5 bits (62), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 19/65 (29%), Positives = 29/65 (44%), Gaps = 4/65 (6%)
 Frame = -1

Query: 90  KYITDWQNVFRTYDRDNSGMIDKNELKQALSGFGYRLSDQFHDILIRKF----DRQGRGQ 145
           +Y   + N+F   D D+ G I  NELKQ       ++ + F  I++R      D  G G 
Sbjct: 435 QYKKKYTNMFNAIDADSDGKITFNELKQNYGNKMLKMMEPFLTIMMRMLMNNADGDGDGL 256

Query: 146 IAFDD 150
           I   +
Sbjct: 255 ITLQE 241
>03845
          Length = 1326

 Score = 28.9 bits (63), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 17/64 (26%), Positives = 29/64 (45%)
 Frame = +2

Query: 28  LWNVFQRVDKDRSGVISDNELQQALSNGTWTPFNPVTVRSIISMFDRENKAGVNFSEFTG 87
           LW++      +  GVI D E +  L++GT              +F   + +G + S+FT 
Sbjct: 170 LWHILPESALEEKGVIQDQEFESRLASGT-------------PIFIYAHGSGGSRSQFTR 310

Query: 88  VWKY 91
           V+ Y
Sbjct: 311 VYTY 322
>00167
          Length = 2176

 Score = 28.9 bits (63), Expect = 1.4,   Method: Compositional matrix adjust.
 Identities = 14/47 (29%), Positives = 28/47 (59%), Gaps = 7/47 (14%)
 Frame = +3

Query: 145 QIAFDDFIQGC-------IVLQRLTDIFRRYDTDQDGWIQVSYEQYL 184
           +++ D+FI GC       +  + L ++FRR+  D+DG   + +E++L
Sbjct: 777 KLSVDEFIVGCRECRIAKMTSEELNEVFRRF--DKDGTGTLDFEEFL 911

 Score = 28.5 bits (62), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 17/59 (28%), Positives = 25/59 (42%)
 Frame = +3

Query: 94  DWQNVFRTYDRDNSGMIDKNELKQALSGFGYRLSDQFHDILIRKFDRQGRGQIAFDDFI 152
           +   VFR +D+D +G +D  E   AL         +       K D+ G G I  DD +
Sbjct: 843 ELNEVFRRFDKDGTGTLDFEEFLLALRPKMNEFRRKLVKKAFAKMDKTGDGIITADDLV 1019
>18171
          Length = 1131

 Score = 28.5 bits (62), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 16/58 (27%), Positives = 26/58 (44%)
 Frame = +3

Query: 28  LWNVFQRVDKDRSGVISDNELQQALSNGTWTPFNPVTVRSIISMFDRENKAGVNFSEF 85
           +      +DKD++GVIS   L+  L+           V  +I   D+E    V++ EF
Sbjct: 171 MLEALTLLDKDQTGVISTALLRHVLTT-LGDQLTSEEVEELIKEADKEETGQVDYKEF 341
>17810
          Length = 667

 Score = 27.7 bits (60), Expect = 3.3,   Method: Compositional matrix adjust.
 Identities = 11/33 (33%), Positives = 17/33 (51%)
 Frame = +3

Query: 26  SFLWNVFQRVDKDRSGVISDNELQQALSNGTWT 58
           S  WN+ + V +D  GV +D E +   +   WT
Sbjct: 84  SVAWNLXKNVSRDHPGVGADGEGEGHAAESQWT 182
>07678
          Length = 958

 Score = 26.9 bits (58), Expect = 5.5,   Method: Compositional matrix adjust.
 Identities = 18/58 (31%), Positives = 30/58 (51%), Gaps = 4/58 (6%)
 Frame = +1

Query: 99  FRTYDRDNSGMIDKNELKQALSGFGYRLSDQFHDILIRK----FDRQGRGQIAFDDFI 152
           F+  D D +  +D  E K+ ++ FG     QF   +I++    FD+   G I FD+F+
Sbjct: 337 FKIMDDDGNRSLDFKEFKKGITEFGLT---QFEGDVIQEMFTCFDKDZSGTIDFDEFL 501
>02929
          Length = 1353

 Score = 26.2 bits (56), Expect = 10.0,   Method: Compositional matrix adjust.
 Identities = 16/61 (26%), Positives = 29/61 (47%)
 Frame = +2

Query: 92  ITDWQNVFRTYDRDNSGMIDKNELKQALSGFGYRLSDQFHDILIRKFDRQGRGQIAFDDF 151
           +TD+   FR  D+D  G + + E    +    +  +    + +   FDR+ RG I + DF
Sbjct: 182 VTDF---FRRQDKDGDGFLTEEEFVNGMMQSRFPTNRTELNAVFDIFDREKRGLIEYKDF 352

Query: 152 I 152
           +
Sbjct: 353 V 355
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|188219524|ref|NP_036123.3|
dihydropyrimidinase-related protein 4 [Mus musculus]
         (572 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

14768                                                                 216   2e-69
34622                                                                 155   4e-38
29305                                                                  40   0.002
35175                                                                  32   0.64 
19962                                                                  29   5.3  
>14768
          Length = 697

 Score =  216 bits (551), Expect(2) = 2e-69,   Method: Compositional matrix adjust.
 Identities = 101/167 (60%), Positives = 130/167 (77%)
 Frame = -1

Query: 316 HLTSLLSSGDLQVTGSAHCTFTTAQKAVGKDNFTLIPEGVNGIEERMSVVWEKCVASGKM 375
           +L  LL++ DLQVTG+ +CTF   QKA+GKD+F  IP GVNG+E+RMSV+WEK V SGKM
Sbjct: 505 YLMDLLANNDLQVTGTDNCTFRADQKALGKDDFRSIPNGVNGVEDRMSVIWEKGVQSGKM 326

Query: 376 DENEFVAVTSTNAAKIFNFYPRKGRVAVGSDADLVIWNPRATKVISAKSHNLNVEYNIFE 435
           D   FVAVTS+ AAKIFN YPRKGR+AVGSDAD+V+W+   T+ ISA++H+  V++NIFE
Sbjct: 325 DACRFVAVTSSAAAKIFNIYPRKGRIAVGSDADVVVWDGNQTRTISAETHHQAVDFNIFE 146

Query: 436 GVECRGVPTVVISQGRVVLEDGNLLVTPGAGRFIPRKTFPDFVYKRI 482
           G++C GVP  VI  G VV+++G + VT G+GRFIP   FP+ VY RI
Sbjct: 145 GLQCHGVPVYVIXNGNVVVDNGEVKVTKGSGRFIPSPCFPEAVYGRI 5

 Score = 65.1 bits (157), Expect(2) = 2e-69,   Method: Compositional matrix adjust.
 Identities = 28/51 (54%), Positives = 39/51 (76%)
 Frame = -2

Query: 252 VTKVMSKGAADMVAQAKRRGVVVFGEPITASLGTDGSHYWSKNWAKAAAFV 302
           V  +MSK +AD+++ ++R+G VVFGEPI ASLGTDG+H W++ W  AA  V
Sbjct: 696 VVHIMSKSSADVISASRRKGKVVFGEPIAASLGTDGTHQWNRCWRHAAGHV 544
>34622
          Length = 477

 Score =  155 bits (393), Expect = 4e-38,   Method: Compositional matrix adjust.
 Identities = 71/128 (55%), Positives = 96/128 (75%)
 Frame = -3

Query: 360 ERMSVVWEKCVASGKMDENEFVAVTSTNAAKIFNFYPRKGRVAVGSDADLVIWNPRATKV 419
           +RMSV+WEK V  GKMD   FVA TS NAA+I+N YPRKGR+AVGSDAD+V+W+   T+ 
Sbjct: 475 DRMSVIWEKGVMMGKMDACRFVAATSANAARIYNIYPRKGRIAVGSDADVVVWDGNQTRT 296

Query: 420 ISAKSHNLNVEYNIFEGVECRGVPTVVISQGRVVLEDGNLLVTPGAGRFIPRKTFPDFVY 479
           ISA++H+  V++NIFEG++C GVP  V+S G+VV++DG L VT G GR +      + VY
Sbjct: 295 ISAETHHQAVDFNIFEGLQCHGVPVYVVSNGQVVVDDGQLKVTQGLGRLVSTPCNAETVY 116

Query: 480 KRIKARNR 487
            R+KAR++
Sbjct: 115 GRVKARDQ 92
>29305
          Length = 881

 Score = 40.0 bits (92), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 19/24 (79%), Positives = 20/24 (83%)
 Frame = -3

Query: 86  ADDFCQGTKAALAGGTTMILDHVF 109
            DDF  GTKAALAGGTTMI+D VF
Sbjct: 879 CDDFYIGTKAALAGGTTMIMDFVF 808
>35175
          Length = 597

 Score = 32.0 bits (71), Expect = 0.64,   Method: Compositional matrix adjust.
 Identities = 20/76 (26%), Positives = 39/76 (51%), Gaps = 3/76 (3%)
 Frame = -2

Query: 145 HESTKEELEALVRDKGVNSFLVFMAYKDRCQCTDGQIYEIFSLIRDLGAVAQ---VHAEN 201
           H+S +EE+EA  ++K   S+  ++   DR +  +     IFS + +L   +     HA N
Sbjct: 452 HDSQEEEVEAGGKEKVEFSYASYLREIDREEILNNTDESIFSSLPELTGXSSKDLSHANN 273

Query: 202 GDIVEEEQKRLLEQGI 217
            D+  +++ +  E+G 
Sbjct: 272 SDMASKDEGQQSEEGT 225
>19962
          Length = 410

 Score = 28.9 bits (63), Expect = 5.3,   Method: Compositional matrix adjust.
 Identities = 24/76 (31%), Positives = 36/76 (47%), Gaps = 10/76 (13%)
 Frame = +3

Query: 479 YKRIKARNRLAEIHGVPRGLYDGPVHEVMLPAKPGS----------GTQARASCSGKISV 528
           ++R ++R   A +HGV      GP     +P+ PGS            Q  ASC+ +   
Sbjct: 108 WRRCESRGPPAALHGV-----AGP--RSAVPSDPGSILVLRHPAARSAQWAASCTLQRGH 266

Query: 529 PPVRNLHQSGFSLSGS 544
            P RNLH++G + S S
Sbjct: 267 RPHRNLHRAGHADSSS 314
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31560504|ref|NP_038486.2| adducin 2 (beta) [Mus
musculus]
         (725 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

08503                                                                 232   2e-69
12858                                                                 192   3e-53
06772                                                                  48   1e-05
>08503
          Length = 985

 Score =  232 bits (591), Expect(3) = 2e-69,   Method: Compositional matrix adjust.
 Identities = 105/234 (44%), Positives = 165/234 (70%), Gaps = 1/234 (0%)
 Frame = +3

Query: 112 MTPINDLHTADSLNLAKGERLMRCKISSVYRLLDLYGWAQLSDTYVTLRVSKEQDHFLIS 171
           + P+ND+   ++   +K E+++RCK+++ YRL+DL+ W      ++++RVS+EQ+ FL++
Sbjct: 138 VIPVNDIRGVETFGYSKQEKVLRCKLAACYRLIDLFXWTNGIHDHISMRVSQEQEQFLVN 317

Query: 172 PKGVSCSEVTASSLIKVNILGEVVEKGSSCFPVDTTGFSLHSAIYAARPDVRCAIHLHTP 231
           P G+  SE+TAS+L KV++ GEVV+ GS+   +   GF+LHSA++ ARPD+RC IHLHT 
Sbjct: 318 PHGMLYSEMTASTLAKVDVRGEVVDTGSTGLGISKAGFTLHSALHQARPDLRCIIHLHTA 497

Query: 232 ATAAVSAMKCGLLPVSHNALLVGDMAYYDFNGEMEQEADRINLQKCLGPTCKILVLRNHG 291
              AVSA KCGLLP+S  A++ G ++Y+D+ G +  + DR  L +CLGP  K++ LRNHG
Sbjct: 498 NVVAVSATKCGLLPISQEAMICGKISYHDYPGPLTDQEDRDQLGRCLGPFNKVMFLRNHG 677

Query: 292 MVALGDTVEEAFYKVFHLQAACEVQVSALSSAGGTENLILLEQE-KHRPHEVGS 344
           ++  G+T+EEAF+  F++ AA E QV  +    G +NLIL+++E + R  +VGS
Sbjct: 678 VLVCGETIEEAFHYAFNVMAAVETQVKVMVV--GLDNLILVDEETQERTFKVGS 833

 Score = 49.7 bits (117), Expect(3) = 2e-69,   Method: Compositional matrix adjust.
 Identities = 20/41 (48%), Positives = 31/41 (75%)
 Frame = +2

Query: 356 QKSRLGEHEFEALMRMLDNLGYRTGYTYRHPFVQEKTKHKS 396
           ++ R GE E+EALMR LDN GYRTG+ Y+ P ++++ K ++
Sbjct: 863 RRWRCGELEWEALMRTLDNSGYRTGHLYKQPLMKQEKKERT 985

 Score = 21.6 bits (44), Expect(3) = 2e-69,   Method: Compositional matrix adjust.
 Identities = 7/15 (46%), Positives = 12/15 (80%)
 Frame = +2

Query: 65 EELEGLIQEQMKKGN 79
          +ELE ++QEQ++ G 
Sbjct: 2  DELEAVVQEQIRPGR 46
>12858
          Length = 851

 Score =  192 bits (487), Expect(2) = 3e-53,   Method: Compositional matrix adjust.
 Identities = 96/195 (49%), Positives = 134/195 (68%), Gaps = 2/195 (1%)
 Frame = +1

Query: 208 GFSLHSAIYAARPDVRCAIHLHTPATAAVSAMKCGLLPVSHNALLVGDMAYYDFNGEMEQ 267
           GF+LHSAI+ ARPD+RC IHLHTPA  AVSA K GLLPVSH AL+ G ++Y+D+NG +  
Sbjct: 1   GFTLHSAIHQARPDIRCIIHLHTPAAVAVSATKQGLLPVSHQALMCGKVSYHDYNGILVD 180

Query: 268 EADRINLQKCLGPTCKILVLRNHGMVALGDTVEEAFYKVFHLQAACEVQVSALSSAGGTE 327
           + +R  L + LGP  K++ LRNHG+V  G+++EEAF+  F++ AAC+VQ+  +    G +
Sbjct: 181 QEERDQLARNLGPFNKVMFLRNHGVVTCGESIEEAFHFAFNVMAACDVQMKVMPV--GID 354

Query: 328 NLILLEQEKHRPHEVGSVQWAGSTFGPMQKSRLGEHEFEALMRMLDNLGYRTGYTYRHPF 387
           NL+LL++E          Q    + G  +K R GE EFEALMR LDN GYRTG+ Y+ P 
Sbjct: 355 NLVLLDEETQEKTYKAGRQTGTDSSG--RKWRCGELEFEALMRTLDNSGYRTGHVYKQPL 528

Query: 388 VQEKTKHK--SEVEI 400
           ++++ K K  S+VE+
Sbjct: 529 MKQEKKEKMNSDVEV 573

 Score = 35.4 bits (80), Expect(2) = 3e-53,   Method: Compositional matrix adjust.
 Identities = 20/66 (30%), Positives = 34/66 (51%), Gaps = 2/66 (3%)
 Frame = +3

Query: 424 QKQQKEKTRWLNTPNTYLRVNVADEVQRNMGSPRPK--TTWMKADEVEKSSSGMPIRIEN 481
           +++Q  K  WL +PN Y +  + +     +G+  PK  T W+   E     +   I+++N
Sbjct: 660 RQKQAYKAGWLTSPNAYKKQEIEE-----IGTTTPKKITKWVPGGEATDQKT-TAIKVDN 821

Query: 482 PNQFVP 487
           PNQF P
Sbjct: 822 PNQFAP 839
>06772
          Length = 996

 Score = 48.1 bits (113), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 42/155 (27%), Positives = 75/155 (48%), Gaps = 31/155 (20%)
 Frame = +2

Query: 451 RNMGSPRPKTTWMKADEVEKSS--------SGMP-----------IRIENPNQFVPLYTD 491
           R  GSP P  T +K+ ++ +S+        SG+P           I++ENPNQF P  ++
Sbjct: 47  RQGGSPHP--TPIKSTKLRRSAPPRPRKLPSGVPGGEQANQKSTAIKVENPNQFAPQGSN 220

Query: 492 PQEVLDMRNKIREQNRQDIKSAGPQSQLLASV-IAEKSRSPSTESQLMSKGDADT----K 546
           P+E  D +  I++   ++  SAGP S++L  +   E ++      Q +  G A      +
Sbjct: 221 PKEFRDKQKSIKKDYYEERVSAGPTSKILDGISWDEAAKMKEGGDQTVVVGAASKGIIQR 400

Query: 547 DESEETV-------PNPFSQLTDQELEEYKKEVER 574
           D     V        NPF  + +++++ YK++V+R
Sbjct: 401 DHQHNAVVFRSYYAANPFENIAEEDMDAYKQQVDR 505
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|94396776|ref|XP_991516.1| PREDICTED: similar to
oxoglutarate dehydrogenase-like isoform 1 [Mus musculus]
         (1007 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

15717                                                                 260   2e-69
33389                                                                  72   8e-13
18709                                                                  30   6.1  
>15717
          Length = 470

 Score =  260 bits (664), Expect = 2e-69,   Method: Compositional matrix adjust.
 Identities = 119/156 (76%), Positives = 136/156 (87%)
 Frame = -2

Query: 651 EGIHVRLSGQDVERGTFSHRHHVLHDQEVDRRTCVPMNHLWPDQAPYTVCNSSLSEYGVL 710
           EGIHVRLSGQDVE GTFSHRHHVLH QE+D++  VP+NH++ DQA Y+VCNSSLSEYGVL
Sbjct: 469 EGIHVRLSGQDVEXGTFSHRHHVLHHQEIDKKMFVPLNHMFEDQAEYSVCNSSLSEYGVL 290

Query: 711 GFELGYAMASPNALVLWEAQFGDFHNTAQCIIDQFISTGQAKWVRHNGIVLLLPHGMEGM 770
           GFELGY+M +PNALV+WEAQFGDF NTAQCIIDQFIS+GQAKWVR +G+VLLLPHG EGM
Sbjct: 289 GFELGYSMTNPNALVIWEAQFGDFANTAQCIIDQFISSGQAKWVRQSGLVLLLPHGYEGM 110

Query: 771 GPEHSSARPERFLQMSNDDSDAYPVFTEDFEVSQLY 806
           GPEHSS R ERFLQ SNDD D +PV   + E+ QL+
Sbjct: 109 GPEHSSCRIERFLQQSNDDPDYFPVEDMNLEIQQLH 2
>33389
          Length = 894

 Score = 72.4 bits (176), Expect = 8e-13,   Method: Composition-based stats.
 Identities = 34/71 (47%), Positives = 44/71 (61%), Gaps = 3/71 (4%)
 Frame = +1

Query: 930 KYSGAELVWCQEEHKNMGYYDYISPRFMTL---LGHSRPIWYVGRDPAAAPATGNKNAHL 986
           KY  A++ W QEEHKNMG Y Y+ PR  T+   +   R + Y GR P+AA ATGNK  H+
Sbjct: 64  KYPKAKVCWVQEEHKNMGPYQYVEPRMRTVFKKMNDVRELEYAGRFPSAAAATGNKQMHV 243

Query: 987 VSLRRFLDTAF 997
           + L  F+D A 
Sbjct: 244 IELSTFMDAAL 276
>18709
          Length = 501

 Score = 29.6 bits (65), Expect = 6.1,   Method: Compositional matrix adjust.
 Identities = 16/42 (38%), Positives = 22/42 (52%)
 Frame = +2

Query: 347 NRNITLSLVANPSHLEAVDPVVQGKTKAEQFYRGDAQGRKVM 388
           N NIT SL+ NP    A+DPV       ++F R +    +VM
Sbjct: 47  NGNITYSLLENPESAFAIDPVTGTLRAMKKFDRENRSHYRVM 172
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|26340446|dbj|BAC33886.1| unnamed protein product [Mus
musculus]
         (293 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

00770                                                                 257   3e-69
02347                                                                  27   8.4  
>00770
          Length = 1465

 Score =  257 bits (657), Expect = 3e-69,   Method: Compositional matrix adjust.
 Identities = 123/259 (47%), Positives = 175/259 (67%), Gaps = 3/259 (1%)
 Frame = +2

Query: 36  PGRITWSELSESGLPL-CDVVINLAGENILNPLRRWNETFQKEVLTSRLDTTHLLAKAIT 94
           P RITWS+L  SGLP     +++L+GENILNP +RWN+ F+K V +SR+D T  LA A+ 
Sbjct: 2   PNRITWSDLERSGLPXDYSAIVSLSGENILNPTKRWNDAFKKAVWSSRVDCTKALADAVR 181

Query: 95  ETAHPPQAWILVTGVAYYQPSLTKEYDEDSPGGNFDFFSNLVTKWEAAARLPGE-STRQX 153
           ++ +PPQ ++ ++GV YY+P  T +YDEDS GG+FD+ S L T WEAAA LP   + RQ 
Sbjct: 182 QSNNPPQVFVSMSGVGYYKPDPTAQYDEDSAGGDFDYLSELCTAWEAAANLPPSLNIRQV 361

Query: 154 XXXXXXXXXXXXXAISHMLLPFRLGLGGPIGSGRQFFPWIHIGDLAGILNYALEANHVQG 213
                         I  +  PF +G+GG IGSG+Q+FPWIH+ D+AGI+ +A+  + V G
Sbjct: 362 IVRSGVVLGRDGGMIQQIYWPFFMGVGGRIGSGQQWFPWIHVEDIAGIITHAITDDSVSG 541

Query: 214 VLNGVAPASTTTNAEFAQALGAALGRPAFIPVPSTVVRAVFG-ERAIMLLEGQKVVPRRT 272
           +LNGVAP    TN +F +A  +++ RPA  PVP  V+  V+G ER  ++LEGQKV P+RT
Sbjct: 542 ILNGVAP-QPATNTDFTKAFASSMXRPALFPVPGFVMNTVYGPERGKVILEGQKVSPKRT 718

Query: 273 LATGYQYSFPELRAALKDV 291
           L +GY+++FP+L +A K +
Sbjct: 719 LESGYKFAFPDLTSACKSL 775
>02347
          Length = 928

 Score = 27.3 bits (59), Expect = 8.4,   Method: Compositional matrix adjust.
 Identities = 12/46 (26%), Positives = 24/46 (52%)
 Frame = -2

Query: 8   GTGFIGTAVTQLLRGRGHEVKLVSRQPGPGRITWSELSESGLPLCD 53
           G   +   + Q+ +GRG + +++ ++P    I WS L    +P C+
Sbjct: 432 GPRPLCLRLLQIPQGRGKQAQVLQQKPLSIPIPWSPLQPKPIPQCE 295
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|7304855|ref|NP_038484.1| actinin alpha 3 [Mus
musculus]
         (900 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

19002                                                                 259   3e-69
19147                                                                 190   2e-51
17613                                                                 179   4e-45
29426                                                                 134   1e-31
29446                                                                  99   1e-20
05733                                                                  82   7e-16
34417                                                                  76   5e-14
32371                                                                  50   5e-11
14594                                                                  59   7e-09
18202                                                                  51   2e-06
18556                                                                  49   8e-06
09711                                                                  49   1e-05
01375                                                                  48   2e-05
20251                                                                  45   1e-04
04951                                                                  41   0.002
32088                                                                  39   0.008
38338                                                                  39   0.008
14366                                                                  36   0.074
28965                                                                  35   0.13 
38533                                                                  35   0.14 
03732                                                                  32   0.80 
12091                                                                  30   3.3  
14027                                                                  30   4.0  
>19002
          Length = 842

 Score =  259 bits (662), Expect = 3e-69,   Method: Compositional matrix adjust.
 Identities = 140/283 (49%), Positives = 181/283 (63%), Gaps = 8/283 (2%)
 Frame = -2

Query: 74  NGLKLMLLLEVISGERLPRPDKGKMRFHKIANVNKALDFIASKGVKLVSIGAEEIVDGNL 133
           +G  LM LLEV     +    KGKMR H + NV+KAL F+  + V L ++GA +IVDG+ 
Sbjct: 841 DGKMLMKLLEVRVRGEIASDXKGKMRIHCLENVDKALTFLHEQRVHLENMGAHDIVDGSS 662

Query: 134 KMTLGMIWTIILRFAIQDISVEET------SAKEGLLLWCQRKTAPYRNVNVQNFHTSWK 187
           ++TLG+IWTIILRF IQDI +EE       SAK+ LLLWCQ KTA Y NVNV+NF TSW+
Sbjct: 661 RLTLGLIWTIILRFQIQDIMIEEVDNSETKSAKDALLLWCQMKTAGYPNVNVRNFTTSWR 482

Query: 188 DGLALCALIHRHRPDLIDYAKLRKDDPIGNLNTAFEVAEKYLDIPKMLDAEDIVNTPKPD 247
           DGLA  A+IH+HRPDL+ Y +L K   I NL  AF VAE  L +  +L+ ED VN   PD
Sbjct: 481 DGLAFNAIIHKHRPDLVQYDRLHKSSAIQNLQNAFTVAEDKLGLTALLEPED-VNVEYPD 305

Query: 248 EKAIMTYVSCFYHXXXXXXXXXXXXNRICKVL--AVNQENEKLMEEYEKLASELLEWIRR 305
           EK+I+TYV  +YH             RI KV+  A+N EN   +EEYE L S+LLEWI +
Sbjct: 304 EKSIITYVVTYYHYFSKMKADSVQGKRIGKVIDNAINTENS--IEEYETLTSDLLEWIEQ 131

Query: 306 TVPWLENRVGEPSMSAMQRKLEDFRDYRRLHKPPRVQEKCQLE 348
           T+  L +R    S++ +Q++L  F  YR + KPP+  EK  LE
Sbjct: 130 TIVILRDRQFANSLTGVQQQLAAFNTYRIVEKPPKFDEKGNLE 2
>19147
          Length = 474

 Score =  190 bits (483), Expect(2) = 2e-51,   Method: Compositional matrix adjust.
 Identities = 90/113 (79%), Positives = 99/113 (87%)
 Frame = +1

Query: 111 DFIASKGVKLVSIGAEEIVDGNLKMTLGMIWTIILRFAIQDISVEETSAKEGLLLWCQRK 170
            +IASKGVKLVSIGAEEIVDGN+KMTLGMIWTIILRFAIQDI+VEE +AKEGLLLWCQRK
Sbjct: 46  SYIASKGVKLVSIGAEEIVDGNVKMTLGMIWTIILRFAIQDITVEELTAKEGLLLWCQRK 225

Query: 171 TAPYRNVNVQNFHTSWKDGLALCALIHRHRPDLIDYAKLRKDDPIGNLNTAFE 223
           TAPY+NVNVQNFH S+KDGLA CALIHRHRP+LIDY  L K   +  LNT  +
Sbjct: 226 TAPYKNVNVQNFHLSFKDGLAFCALIHRHRPELIDYHSLSK---VSLLNTVVQ 375

 Score = 32.0 bits (71), Expect(2) = 2e-51,   Method: Composition-based stats.
 Identities = 14/16 (87%), Positives = 15/16 (93%)
 Frame = +3

Query: 97  KMRFHKIANVNKALDF 112
           KMRFHKIANVNKAL+ 
Sbjct: 3   KMRFHKIANVNKALEL 50
>17613
          Length = 1108

 Score =  179 bits (455), Expect = 4e-45,   Method: Compositional matrix adjust.
 Identities = 79/127 (62%), Positives = 110/127 (86%)
 Frame = +2

Query: 339 PRVQEKCQLEINFNTLQTKLRLSHRPAFMPSEGKLVSDIANAWRGLEQVEKGYEDWLLSE 398
           P++++K +LE +FNTLQT+LRLS+RPA++P+EGK+VSDIANAW+GLE  EKG+E+WLLSE
Sbjct: 725 PKLEDKAKLENSFNTLQTRLRLSNRPAYLPTEGKMVSDIANAWKGLEHAEKGFEEWLLSE 904

Query: 399 IRRLQRLQHLAEKFQQKASLHEAWTRGKEEMLNQHDYESASLQEVRALLRRHEAFESDLA 458
           ++RL+RL HLA+KF+ K  +HE W++GKE+ML   D++   L E++A+ ++HEAFESDLA
Sbjct: 905 LQRLERLDHLAQKFRHKCEIHEEWSQGKEDMLQSRDFKQCRLNELKAMKKKHEAFESDLA 1084

Query: 459 AHQDRVE 465
           AHQDRVE
Sbjct: 1085AHQDRVE 1105

 Score =  158 bits (399), Expect = 1e-38,   Method: Compositional matrix adjust.
 Identities = 77/145 (53%), Positives = 98/145 (67%)
 Frame = +3

Query: 215 IGNLNTAFEVAEKYLDIPKMLDAEDIVNTPKPDEKAIMTYVSCFYHXXXXXXXXXXXXNR 274
           IG     F    K+LDIP+MLD ED+VN+ KPDE+++M YVS +YH            NR
Sbjct: 354 IGEPQHCF*HRRKHLDIPRMLDPEDMVNSAKPDERSVMAYVSSYYHAFSGAQQAETAANR 533

Query: 275 ICKVLAVNQENEKLMEEYEKLASELLEWIRRTVPWLENRVGEPSMSAMQRKLEDFRDYRR 334
           ICKVL VNQENE+LMEEYE+LAS+LLEWIRRT PWLENRV + ++   + KL++FRDYRR
Sbjct: 534 ICKVLKVNQENERLMEEYERLASDLLEWIRRTRPWLENRVTDNTLPGTRHKLDEFRDYRR 713

Query: 335 LHKPPRVQEKCQLEINFNTLQTKLR 359
             KPP  + +     ++ TL T  R
Sbjct: 714 KQKPPSWRTR----PSWRTLSTPCR 776

 Score =  114 bits (285), Expect = 2e-25,   Method: Compositional matrix adjust.
 Identities = 62/133 (46%), Positives = 78/133 (58%), Gaps = 4/133 (3%)
 Frame = +1

Query: 98  MRFHKIANVNKALDFI----ASKGVKLVSIGAEEIVDGNLKMTLGMIWTIILRFAIQDIS 153
           MRFHKIANVNKALD+I       G+             +++  L     +          
Sbjct: 4   MRFHKIANVNKALDYIDLQRGQTGLHRSRRNC*RQRKDDIRYDLDNYPQV----CHPRHH 171

Query: 154 VEETSAKEGLLLWCQRKTAPYRNVNVQNFHTSWKDGLALCALIHRHRPDLIDYAKLRKDD 213
              T  +   ++    KTAPY+NVNVQNFH S+KDGLA CALIHRHRP+LIDY  L KD+
Sbjct: 172 SRRTHCQRRTVIVVPAKTAPYKNVNVQNFHLSFKDGLAFCALIHRHRPELIDYHSLSKDN 351

Query: 214 PIGNLNTAFEVAE 226
           P+ NLNTAF++AE
Sbjct: 352 PLENLNTAFDIAE 390
>29426
          Length = 361

 Score =  134 bits (338), Expect = 1e-31,   Method: Compositional matrix adjust.
 Identities = 66/121 (54%), Positives = 85/121 (70%), Gaps = 1/121 (0%)
 Frame = -2

Query: 550 LVHSVEETQSLLTAHEQFKATLPEADRERGAILGIQGEIQKICQTYGLRPKSGNPYITLS 609
           +VH+ EE + L+ AHEQFKATL EAD+E   I+ +  E+  + Q Y L P   NPY TL 
Sbjct: 360 IVHTTEEVEGLVDAHEQFKATLGEADKEYSTIVSLSQEVASLGQQYDLTPPD-NPYTTLH 184

Query: 610 SQ-DINNKWDTVRKLVPSRDQTLQEELARQQVNERLRRQFAAQANAIGPWIQGKVEEVGR 668
           +Q DI NKW  VR+LVP RDQTLQ+E+ RQQ NERLRRQFA +AN +G WI+ +++ V  
Sbjct: 183 AQEDITNKWSEVRELVPRRDQTLQQEMTRQQNNERLRRQFATKANTVGQWIESQLDAVAS 4

Query: 669 L 669
           L
Sbjct: 3   L 1
>29446
          Length = 1445

 Score = 98.6 bits (244), Expect = 1e-20,   Method: Compositional matrix adjust.
 Identities = 60/165 (36%), Positives = 90/165 (54%), Gaps = 11/165 (6%)
 Frame = +3

Query: 33   DRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRNGLKLMLLLEVISGERLPR 92
            +R+L  D  W+  Q+ TFT W N HLR     I ++E DF +GL+L+ L+EV+SG++   
Sbjct: 963  ERELAEDAQWKIIQKNTFTRWANEHLRTVNKAIADLESDFSDGLRLVALIEVLSGKKFKH 1142

Query: 93   PDK-GKMRFHKIANVNKALDFIA-SKGVKLVSIGAEEIVDGNLKMTLGMIWTIILRFAIQ 150
             +K    R  K+ NV   L F+   +G+++V+I + +IVD  LK+ LG+IWT+IL ++I 
Sbjct: 1143 VNKRPNFRTQKLENVTLTLKFLEDDEGIRIVNIDSTDIVDKKLKLILGLIWTLILHYSIS 1322

Query: 151  DI--SVEETSAKEG-------LLLWCQRKTAPYRNVNVQNFHTSW 186
                  EE +  EG       LL W Q K      +  Q  H  W
Sbjct: 1323 MPMWEGEEPTPSEGGPTPKQRLLNWIQSKVP----IAHQELHHRW 1445
>05733
          Length = 1021

 Score = 82.4 bits (202), Expect = 7e-16,   Method: Compositional matrix adjust.
 Identities = 41/99 (41%), Positives = 59/99 (59%), Gaps = 2/99 (2%)
 Frame = +2

Query: 163 LLLWCQR--KTAPYRNVNVQNFHTSWKDGLALCALIHRHRPDLIDYAKLRKDDPIGNLNT 220
           LL WCQR      YR V++ +F +SW+ GLA CALIH  RP LI  A L + + + N   
Sbjct: 470 LLRWCQRVLNXGTYRGVHIIDFTSSWRSGLAFCALIHAFRPHLISPASLMECETVKNNQL 649

Query: 221 AFEVAEKYLDIPKMLDAEDIVNTPKPDEKAIMTYVSCFY 259
           AF+VA+K L I  ++  ED+     PD+  ++ Y+S F+
Sbjct: 650 AFDVAQKELGIAPVMRGEDMAACAVPDKLTMVAYLSQFH 766
>34417
          Length = 1096

 Score = 76.3 bits (186), Expect = 5e-14,   Method: Composition-based stats.
 Identities = 34/76 (44%), Positives = 45/76 (59%)
 Frame = +2

Query: 184 TSWKDGLALCALIHRHRPDLIDYAKLRKDDPIGNLNTAFEVAEKYLDIPKMLDAEDIVNT 243
           + W +GLA CALIH   PD  DY++L+  +   N   AF+ AEK  DI  +LD ED++  
Sbjct: 41  SCWNNGLAFCALIHHFYPDAFDYSQLQPQNRRYNFELAFDTAEKLADISPLLDVEDMIKM 220

Query: 244 PKPDEKAIMTYVSCFY 259
             PD K + TYV  FY
Sbjct: 221 KNPDWKCVFTYVQSFY 268
>32371
          Length = 625

 Score = 50.1 bits (118), Expect(2) = 5e-11,   Method: Compositional matrix adjust.
 Identities = 25/48 (52%), Positives = 32/48 (66%)
 Frame = -2

Query: 201 PDLIDYAKLRKDDPIGNLNTAFEVAEKYLDIPKMLDAEDIVNTPKPDE 248
           PDLIDY  L K++ + N N AF VAE+ LDIP  L+A D+V    PD+
Sbjct: 549 PDLIDYDSLSKENVLYNNNLAFTVAEQELDIPAFLEAADMVALRTPDK 406

 Score = 36.2 bits (82), Expect(2) = 5e-11,   Method: Composition-based stats.
 Identities = 12/25 (48%), Positives = 20/25 (80%)
 Frame = -1

Query: 176 NVNVQNFHTSWKDGLALCALIHRHR 200
           +V++++   SW++GLA CA+IHR R
Sbjct: 625 SVDIKDLLVSWRNGLAFCAIIHRFR 551
>14594
          Length = 1014

 Score = 59.3 bits (142), Expect = 7e-09,   Method: Compositional matrix adjust.
 Identities = 31/104 (29%), Positives = 57/104 (54%), Gaps = 1/104 (0%)
 Frame = +3

Query: 756 LSQEQLNEFRASFNHFDRKRNGMMEPDDFRACLISMGYDLGEVEFARIMTMVDPNAAGVV 815
           L+ EQ+ EF+ +F+ FD+  +G +   +    + S+G +  E E   ++  VD +  G +
Sbjct: 423 LTDEQVAEFKEAFSLFDKDGDGTITTSELGTVMRSLGQNPTENELQDMINEVDADGNGTI 602

Query: 816 TFQAFIDFMTRETAETDTAEQVVASFKILAGDKN-YITPEELRR 858
            F+ F+  M R+  +TD  E++  +F++   D N YI+  ELR 
Sbjct: 603 DFEEFLHMMARKMKDTDCEEELREAFRVFDKDGNGYISAAELRH 734
>18202
          Length = 424

 Score = 51.2 bits (121), Expect = 2e-06,   Method: Composition-based stats.
 Identities = 36/127 (28%), Positives = 69/127 (54%), Gaps = 6/127 (4%)
 Frame = -1

Query: 48  KTFTAWCNSHLRKAGTQIENIEEDFRNGLKLMLLLEVISGER-LPRPDKGKMRFHKIANV 106
           + + +W NS L +  + +EN+    + G  L  L++V++ E  L    +   +  + A +
Sbjct: 385 QVYLSWANSVLCEVNSSVENVSS-IQEGRVLCELIDVLAPEAGLLDKVQASGKSGQRAFI 209

Query: 107 NKALDFIASKGVKLVSIGAEEIVDGNLKMTLGMIWTIILRFAIQDI---SVEET--SAKE 161
             ALD + + G+K+V    ++I+DG++K  L ++W +IL + I  I   S + +  + K+
Sbjct: 208 YAALDHMKNHGIKIV-FSTQDIMDGDIKSLLDVMWLLILNYGIHFIGNNSFQRSVGAGKK 32

Query: 162 GLLLWCQ 168
            LL WCQ
Sbjct: 31  NLLDWCQ 11
>18556
          Length = 799

 Score = 48.9 bits (115), Expect = 8e-06,   Method: Compositional matrix adjust.
 Identities = 28/78 (35%), Positives = 42/78 (53%), Gaps = 1/78 (1%)
 Frame = +2

Query: 162 GLLLWCQRKTAPYR-NVNVQNFHTSWKDGLALCALIHRHRPDLIDYAKLRKDDPIGNLNT 220
            LL W   + A Y+    ++     +++G  LCALI R RPDLIDYA  +   P+     
Sbjct: 44  SLLRWISVQLAAYQFTAELKEPSDVFRNGRVLCALISRFRPDLIDYAATKDMSPLECNEL 223

Query: 221 AFEVAEKYLDIPKMLDAE 238
           AF V E+ L I +++ A+
Sbjct: 224 AFAVLERELHIDRIMSAK 277
>09711
          Length = 3041

 Score = 48.5 bits (114), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 65/267 (24%), Positives = 112/267 (41%), Gaps = 25/267 (9%)
 Frame = +1

Query: 43   EKQQRKTFTAWCNSHLRKAGTQIENIEEDFRNGLKLMLLLEVIS------GERLPRPDKG 96
            E ++ KT+  W NS        + ++  D  +GL +  L + I        +   + +K 
Sbjct: 841  ESREEKTYRNWMNS--LGVSPFVHHLYSDLYDGLIIFQLYDYIQPGLVDWSKVKKKFNKL 1014

Query: 97   KMRFHKIANVNKALDF---IASKGVKLVSIGAEEIVDGNLKMTLGMIWTIILRFAIQDIS 153
            K RF +I N N A++    +    VKLV I  ++I+DGN  +TLG++W ++  + +  +S
Sbjct: 1015 KARFERIENCNYAVELGPQVKLVKVKLVGIAGQDILDGNPVLTLGLVWQLMRAYTLAILS 1194

Query: 154  -VEETS---AKEGLLLWCQRKTAPYRNVNVQNFHT-SWKDGLALCALIHRHRP-----DL 203
             + E +   +   ++ W   K    ++  +  F      DG+ +  +I   +P     D 
Sbjct: 1195 KITENNKPISDNEIITWVNSKIK--KDDRISGFQDRKLNDGVIVARVIEAIKPGIVNWDN 1368

Query: 204  IDYAKLRKDDPIGNLNTAFEVAEKYLDIPKMLDAEDIVNTPKPDEKAIMTYVSCFYHXXX 263
            ID +     D + N   A  +A K       L  EDIV   KP  K ++T  +C      
Sbjct: 1369 IDCSARDYQDRLTNARYAIGLARKIGAGVYAL-PEDIVEV-KP--KMLLTVFACLMMRDF 1536

Query: 264  XXXXXXXXXN------RICKVLAVNQE 284
                     N       +C+ L VN E
Sbjct: 1537 SSRPAAAEANSH*VWDNVCE*LGVNTE 1617

 Score = 34.3 bits (77), Expect = 0.23,   Method: Compositional matrix adjust.
 Identities = 34/137 (24%), Positives = 56/137 (40%), Gaps = 17/137 (12%)
 Frame = +1

Query: 46  QRKTFTAWCNSHLRKA------------GTQIENIEEDFRNGLKLMLLLE-----VISGE 88
           ++K F  W N HL               GTQ+     D   G+ L  L+       I   
Sbjct: 52  EQKAFAEWINRHLSDXPDCKHLLPLDADGTQLFGQMAD---GVLLCKLINHSVSNTIDER 222

Query: 89  RLPRPDKGKMRFHKIANVNKALDFIASKGVKLVSIGAEEIVDGNLKMTLGMIWTIILRFA 148
            + + +    R H+  N+  A++   + G   V+IG E++  G   + LG++W II    
Sbjct: 223 TINKQNLSLYRRHE--NLTLAVNSAGAIGCTTVNIGPEDLAAGRPHLVLGLLWQIIRIGL 396

Query: 149 IQDISVEETSAKEGLLL 165
           + DI++        LLL
Sbjct: 397 LSDINLAHHPGLVNLLL 447
>01375
          Length = 2323

 Score = 48.1 bits (113), Expect = 2e-05,   Method: Composition-based stats.
 Identities = 29/72 (40%), Positives = 41/72 (56%), Gaps = 4/72 (5%)
 Frame = +1

Query: 828 TAETDTAEQVVASFKIL-AGDKNYITPEELRRELPAEQAEYCIRRMAPY---KGSGAPSG 883
           T    ++ +V  +F+ L +G+K +IT +EL   L  EQA+YCI RM PY    G   P  
Sbjct: 4   TENVQSSSEVEQAFRALTSGEKPFITAQELYANLTKEQADYCIGRMQPYVDKTGRTIPD- 180

Query: 884 ALDYVAFSSALY 895
           A DYV F+  L+
Sbjct: 181 AYDYVDFTRQLF 216
>20251
          Length = 2203

 Score = 45.4 bits (106), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 38/150 (25%), Positives = 63/150 (42%), Gaps = 8/150 (5%)
 Frame = +3

Query: 756 LSQEQLNEFRASFNHFDRKRNGMMEPDDFRACLISMGYDLGEVEFARIMTMVDPNAAGVV 815
             Q Q+ EF+ +FN  D+ R+G ++ +D    L S+G +  E +   +M      A G +
Sbjct: 141 FDQSQIQEFKEAFNMIDQNRDGFIDKEDLGDMLASLGKNPTEGQLDEMMNX----APGPI 308

Query: 816 TFQAFIDFMTRETAETDTAEQVVASFKILAGDKNYITPEELRRELPAEQAEYC------- 868
            F  F+     +   TD  + +  +F     D   +  E+  REL     +         
Sbjct: 309 NFTMFLTMFGDKLNGTDPEDVIKNAFACFDEDGKGVIQEDRLRELLTTMGDRFTDDEVDE 488

Query: 869 IRRMAPYKGSGAPSGALDYVAFSSAL-YGE 897
           + R AP K      G  DY+ F+  L YG+
Sbjct: 489 MFRDAPIK-----RGNFDYLEFTRILKYGK 563
>04951
          Length = 2852

 Score = 41.2 bits (95), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 39/151 (25%), Positives = 70/151 (46%), Gaps = 10/151 (6%)
 Frame = +1

Query: 118 VKLVSIGAEEIVDGNLKMTLGMIWTIILRFAIQDISVEETSAK----EGLLLWCQRKTAP 173
           +KLV IG ++I DGN  +TLG++W ++  + +  +S      K      ++ W   K   
Sbjct: 61  MKLVGIGGKDIHDGNPVLTLGLVWQLMRAYTLAILSKLTEDKKPIQDSEIVDWVNSKVK- 237

Query: 174 YRNVNVQNFHTS-WKDGLALCALIHRHRPDLIDYAKLR-----KDDPIGNLNTAFEVAEK 227
            ++  + +F  S   DG+ +  +I   +P ++++  +       DD + N   A  +A K
Sbjct: 238 -KDERIGSFQDSKLNDGVIVAKVIESIKPGIVNWENINPNASEPDDRLANARYAIGLARK 414

Query: 228 YLDIPKMLDAEDIVNTPKPDEKAIMTYVSCF 258
                  L  EDIV   KP  K ++T  +C 
Sbjct: 415 IGAGVYAL-PEDIVEV-KP--KMLLTVFACL 495
>32088
          Length = 1928

 Score = 39.3 bits (90), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 31/121 (25%), Positives = 58/121 (47%), Gaps = 12/121 (9%)
 Frame = +1

Query: 46   QRKTFTAWCNSHLR-----KAGTQIENIEED-FRNGLKLMLLLEVISGERLPRPDKGKMR 99
            ++K F AW N HL+     K   ++    +D F+     +LL ++I+       D+  + 
Sbjct: 1264 EQKAFAAWINRHLKDDPDCKHLMEVNEEGDDLFKKVGDGILLCKLINHSVSNTIDERAIN 1443

Query: 100  ------FHKIANVNKALDFIASKGVKLVSIGAEEIVDGNLKMTLGMIWTIILRFAIQDIS 153
                  +H+  N+  A++   S G   V+IG E++  G   + LG++W II    + DI+
Sbjct: 1444 KSNLNVYHRHENLTLAVNSAGSIGCTTVNIGPEDLAAGRPHLVLGLLWQIIRIGLLSDIN 1623

Query: 154  V 154
            +
Sbjct: 1624 L 1626
>38338
          Length = 463

 Score = 39.3 bits (90), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 18/65 (27%), Positives = 35/65 (53%)
 Frame = -2

Query: 753 AKGLSQEQLNEFRASFNHFDRKRNGMMEPDDFRACLISMGYDLGEVEFARIMTMVDPNAA 812
           A  L++EQ+ EF+ +F+ FD+  +G +   +    + S+G +  E E   ++  VD +  
Sbjct: 195 ADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGN 16

Query: 813 GVVTF 817
           G + F
Sbjct: 15  GTIDF 1
>14366
          Length = 499

 Score = 35.8 bits (81), Expect = 0.074,   Method: Compositional matrix adjust.
 Identities = 18/69 (26%), Positives = 33/69 (47%)
 Frame = -3

Query: 756 LSQEQLNEFRASFNHFDRKRNGMMEPDDFRACLISMGYDLGEVEFARIMTMVDPNAAGVV 815
            + E  +  R +F  FD++ NGM+   + R  L  +G  L + E   ++   D +  G V
Sbjct: 269 FAPETSDNLREAFRIFDKEGNGMINAAELRHVLTHLGEKLSDEEVDEMIREADISGDGQV 90

Query: 816 TFQAFIDFM 824
           ++  F+  M
Sbjct: 89  SYNDFVKVM 63
>28965
          Length = 421

 Score = 35.0 bits (79), Expect = 0.13,   Method: Compositional matrix adjust.
 Identities = 34/118 (28%), Positives = 54/118 (45%), Gaps = 2/118 (1%)
 Frame = +2

Query: 349 INFNTLQTKLRLSHRPAFMPSEGKLVSDIANAWRGLEQVEKGYEDWLLSEIRRLQRL--Q 406
           +  NTL  +L     P       K   ++  AW+ L Q+           + R +RL   
Sbjct: 35  VEVNTLAEQLVTDGHPEEETIRQKQ-EEVNEAWKRLRQLS----------LLRQERLYGA 181

Query: 407 HLAEKFQQKASLHEAWTRGKEEMLNQHDYESASLQEVRALLRRHEAFESDLAAHQDRV 464
           H  ++F + A    AW + K+ +L+  DY    L  V+ L R+HE  E DLAA +++V
Sbjct: 182 HEIQRFNRDADETIAWIQEKDAVLSTDDY-GRDLASVQTLQRKHEGVERDLAALEEKV 352
>38533
          Length = 380

 Score = 35.0 bits (79), Expect = 0.14,   Method: Compositional matrix adjust.
 Identities = 15/50 (30%), Positives = 31/50 (62%)
 Frame = +1

Query: 439 SLQEVRALLRRHEAFESDLAAHQDRVEHIAALAQELNELDYHEAASVNSR 488
           SL  V+ L+++H+A ES++ AH+  ++ +A  AQ++    +   A + +R
Sbjct: 70  SLTAVQNLMKKHQALESEIVAHEPLIDAVATSAQQMIRTKHFATADIQTR 219
>03732
          Length = 1114

 Score = 32.3 bits (72), Expect = 0.80,   Method: Compositional matrix adjust.
 Identities = 27/114 (23%), Positives = 50/114 (43%)
 Frame = -1

Query: 708  LQESLVFDNKHTVYSMEHIRVGWEQLLTSIARTINEVENQVLTRDAKGLSQEQLNEFRAS 767
            LQ++L  +   T ++ E +R+         + TIN  E Q L +         + +++  
Sbjct: 1036 LQQALS-NGTWTPFNPETVRLMIGMFDRDNSGTINFQEFQALWK--------YVTDWQNC 884

Query: 768  FNHFDRKRNGMMEPDDFRACLISMGYDLGEVEFARIMTMVDPNAAGVVTFQAFI 821
            F  +DR  +G ++ ++ +  L   GY L +  F  ++   D    G V F  FI
Sbjct: 883  FRSYDRDNSGSIDRNELKNALTGFGYRLSDRFFDVLVKKFDRQGKGTVAFDDFI 722
>12091
          Length = 725

 Score = 30.4 bits (67), Expect = 3.3,   Method: Composition-based stats.
 Identities = 19/56 (33%), Positives = 29/56 (51%), Gaps = 1/56 (1%)
 Frame = -1

Query: 129 VDGNLKMTLGMIWTIILRFAIQDISVEETSAKE-GLLLWCQRKTAPYRNVNVQNFH 183
           V  NL +       ++L  AI     + T+AKE GLLL+  + T+  R  N++ FH
Sbjct: 674 VSQNLDLQTMFQIAMLLFLAINMFRRDSTAAKETGLLLYFSQSTSITRKXNLEQFH 507
>14027
          Length = 958

 Score = 30.0 bits (66), Expect = 4.0,   Method: Compositional matrix adjust.
 Identities = 17/43 (39%), Positives = 23/43 (53%), Gaps = 2/43 (4%)
 Frame = -1

Query: 39  DPAWEKQQRKTFTAWCN--SHLRKAGTQIENIEEDFRNGLKLM 79
           +  W KQ +   TA+CN   H+      IENIE+DF+    LM
Sbjct: 514 NXVWSKQTKSDITAFCNYCCHI------IENIEKDFKVQKXLM 404
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|111154109|ref|NP_035067.2| neuroblastoma ras oncogene
[Mus musculus]
         (189 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

00858                                                                 256   4e-69
07580                                                                 166   3e-44
18509                                                                 105   4e-32
19046                                                                  99   1e-21
24619                                                                  96   6e-21
11257                                                                  92   1e-19
26536                                                                  87   2e-18
36482                                                                  85   2e-17
14456                                                                  84   3e-17
06994                                                                  73   4e-17
08428                                                                  76   1e-14
34468                                                                  74   3e-14
33374                                                                  68   2e-12
11728                                                                  62   1e-10
07465                                                                  62   2e-10
01972                                                                  59   1e-09
19656                                                                  58   3e-09
17511                                                                  58   3e-09
13745                                                                  57   5e-09
33380                                                                  57   6e-09
12339                                                                  54   3e-08
19006                                                                  54   5e-08
01398                                                                  54   5e-08
26083                                                                  52   2e-07
34359                                                                  51   3e-07
34597                                                                  48   3e-06
01095                                                                  47   7e-06
32723                                                                  46   7e-06
31291                                                                  46   7e-06
25655                                                                  33   9e-06
31928                                                                  35   0.019
00552                                                                  35   0.023
21396                                                                  32   0.12 
35581                                                                  30   0.48 
10708                                                                  28   2.3  
09309                                                                  28   2.9  
18949                                                                  27   4.9  
>00858
          Length = 1658

 Score =  256 bits (654), Expect = 4e-69,   Method: Compositional matrix adjust.
 Identities = 125/163 (76%), Positives = 136/163 (83%)
 Frame = -2

Query: 1    MTEYKLXXXXXXXXXKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAG 60
            MTEYKL         KSALTIQL QNHFV+EYDPT EDS RKQVVIDGETCLLDILDTAG
Sbjct: 1597 MTEYKLVVVGAGGVGKSALTIQLXQNHFVEEYDPTXEDSXRKQVVIDGETCLLDILDTAG 1418

Query: 61   QEEYSAMRDQYMRTGEGFLCVFAINNSKSFADINLYREQIKRVKDSDDVPMVLVGNKCDL 120
            QEE SAMRDQ MRTGEGFLCVFA+ N KSF DIN YREQIKRVKD+D+VPMVLVGNK DL
Sbjct: 1417 QEEXSAMRDQCMRTGEGFLCVFAVXNLKSFEDINQYREQIKRVKDADEVPMVLVGNKVDL 1238

Query: 121  PTRTVDTKQAHELAKSYGIPFIETSAKTRQGVEDAFYTLVREI 163
            P R V+ +Q   +A+ Y IP++ETSAKTRQGV+DAFYTLVREI
Sbjct: 1237 PIRNVEQRQGKHMAELYHIPYVETSAKTRQGVDDAFYTLVREI 1109
>07580
          Length = 921

 Score =  166 bits (420), Expect(2) = 3e-44,   Method: Compositional matrix adjust.
 Identities = 80/144 (55%), Positives = 104/144 (72%), Gaps = 1/144 (0%)
 Frame = +3

Query: 23  LIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVF 82
           L +  FV++YDPTIEDSYRKQV +DG+ C+L+ILDTAG E+++AMRD YM+ G+GFL  +
Sbjct: 120 LCKGIFVEKYDPTIEDSYRKQVEVDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFLLAY 299

Query: 83  AINNSKSFADINLYREQIKRVKDSDDVPMVLVGNKCDLP-TRTVDTKQAHELAKSYGIPF 141
           +I    +F D+   REQI RVKD+DDVPM+LVGNKCDL   R V   Q   LA+S+   F
Sbjct: 300 SITAQSTFNDLQELREQILRVKDTDDVPMLLVGNKCDLEDERVVGKDQGQGLARSFSCAF 479

Query: 142 IETSAKTRQGVEDAFYTLVREIRQ 165
           +ETSAK R  V + F  LVR+I +
Sbjct: 480 LETSAKARINVNEIFMDLVRQINK 551

 Score = 28.9 bits (63), Expect(2) = 3e-44,   Method: Compositional matrix adjust.
 Identities = 13/28 (46%), Positives = 15/28 (53%)
 Frame = +2

Query: 1  MTEYKLXXXXXXXXXKSALTIQLIQNHF 28
          M EYKL         KSALT+Q +Q  F
Sbjct: 53 MREYKLVVLGSGGVGKSALTVQFVQGDF 136
>18509
          Length = 625

 Score =  105 bits (261), Expect(2) = 4e-32,   Method: Compositional matrix adjust.
 Identities = 47/69 (68%), Positives = 59/69 (85%)
 Frame = -3

Query: 102 RVKDSDDVPMVLVGNKCDLPTRTVDTKQAHELAKSYGIPFIETSAKTRQGVEDAFYTLVR 161
           RVKD+D+VPMVLVGNK DLP R V+ +Q   +A+ Y IP++ETSAKTRQGV+DAFYTLVR
Sbjct: 548 RVKDADEVPMVLVGNKVDLPIRNVEQRQGKHMAELYHIPYVETSAKTRQGVDDAFYTLVR 369

Query: 162 EIRQYRMKK 170
           EIR+Y+ +K
Sbjct: 368 EIRKYKERK 342

 Score = 49.7 bits (117), Expect(2) = 4e-32,   Method: Compositional matrix adjust.
 Identities = 22/26 (84%), Positives = 23/26 (88%)
 Frame = -1

Query: 76  EGFLCVFAINNSKSFADINLYREQIK 101
           EGFLCVFA+NN KSF DIN YREQIK
Sbjct: 625 EGFLCVFAVNNLKSFEDINQYREQIK 548
>19046
          Length = 445

 Score = 99.0 bits (245), Expect = 1e-21,   Method: Compositional matrix adjust.
 Identities = 53/106 (50%), Positives = 70/106 (66%), Gaps = 2/106 (1%)
 Frame = -2

Query: 61  QEEYSAMRDQYMRTGEGFLCVFAINNSKSFADINLYREQIKRVKDSDDVPMVLVGNKCDL 120
           QEE+SAMR+QYMR G+GFL VF++ + +SF ++  +  QI RVKD D  PM+L  NK DL
Sbjct: 444 QEEFSAMREQYMRKGDGFLLVFSVTDFRSFENMANFHTQILRVKDRDSYPMILCANKVDL 265

Query: 121 -PTRTVDTKQAHELAKSYGIPFIETSAKTRQ-GVEDAFYTLVREIR 164
              R V  +Q  +LA    IP+IETSAK     V+ AF+ +VR IR
Sbjct: 264 VHQRKVSEEQVRDLATRLRIPYIETSAKDPPLNVDLAFHQVVRVIR 127
>24619
          Length = 509

 Score = 96.3 bits (238), Expect = 6e-21,   Method: Compositional matrix adjust.
 Identities = 53/106 (50%), Positives = 70/106 (66%), Gaps = 2/106 (1%)
 Frame = -2

Query: 61  QEEYSAMRDQYMRTGEGFLCVFAINNSKSFADINLYREQIKRVKDSDDVPMVLVGNKCDL 120
           QEE+SAMR+QYMR G+GFL VF++ + +SF ++  +  QI RVKD D  PM+L  NK DL
Sbjct: 508 QEEFSAMREQYMRKGDGFLLVFSVIDYQSFENMVNFHTQILRVKDRDTYPMILCANKVDL 329

Query: 121 -PTRTVDTKQAHELAKSYGIPFIETSAKTRQ-GVEDAFYTLVREIR 164
              R V  +Q  +LA    IP+IETSAK     V+ AF+ +VR IR
Sbjct: 328 VHQRKVSEEQVRDLATRLRIPYIETSAKDPPLNVDLAFHQVVRVIR 191
>11257
          Length = 1102

 Score = 92.4 bits (228), Expect = 1e-19,   Method: Compositional matrix adjust.
 Identities = 46/128 (35%), Positives = 77/128 (60%), Gaps = 4/128 (3%)
 Frame = -2

Query: 42   KQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNSKSFADINLYREQI- 100
            K VV+DGET  + I DTAGQE Y ++R  + R  +  L  F+++N KS   ++ + ++  
Sbjct: 1053 KDVVVDGETFTMQIWDTAGQERYKSLRTPFYRGTDCCLLTFSVDNLKSLQSLSDWYDEFV 874

Query: 101  --KRVKDSDDVPMVLVGNKCDLPTRTVDTKQAHELAKSYG-IPFIETSAKTRQGVEDAFY 157
                ++DS   P V++GNK D+  R V ++ A+   +++G +P+ ETSAK    V+ AF 
Sbjct: 873  NYADIQDSASFPFVIIGNKADIEEREVSSEDAYNWCRTHGNLPYFETSAKDSLNVQQAFL 694

Query: 158  TLVREIRQ 165
             +VR +R+
Sbjct: 693  AVVRRLRE 670
>26536
          Length = 829

 Score = 87.0 bits (214), Expect(2) = 2e-18,   Method: Compositional matrix adjust.
 Identities = 43/110 (39%), Positives = 66/110 (60%), Gaps = 1/110 (0%)
 Frame = +2

Query: 55  ILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNSKSFADINLYREQIKRVKDSDDVPMVLV 114
            LDTAGQEEYS+MR+ Y R+G+GF+ V+++ +  SF +       + R +D   +  VL 
Sbjct: 140 FLDTAGQEEYSSMREHYTRSGDGFIVVYSVTDVTSFQEAEAVFRWLTRFQDETSIHAVLC 319

Query: 115 GNKCDLPT-RTVDTKQAHELAKSYGIPFIETSAKTRQGVEDAFYTLVREI 163
           GNK DL + R V  ++  ++A   G+ + ETSAKT   V   ++ L+R I
Sbjct: 320 GNKTDLTSDRKVTPEEGRKMADRLGMLYFETSAKTGDNVSQVYHGLLRSI 469

 Score = 21.2 bits (43), Expect(2) = 2e-18,   Method: Compositional matrix adjust.
 Identities = 8/13 (61%), Positives = 8/13 (61%)
 Frame = +1

Query: 48  GETCLLDILDTAG 60
           GETC LDI    G
Sbjct: 118 GETCFLDIFGHRG 156

 Score = 51.2 bits (121), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 23/48 (47%), Positives = 32/48 (66%)
 Frame = +2

Query: 2   TEYKLXXXXXXXXXKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGE 49
           T+YK+         KS+LTI+  Q+ F+D YDPTIEDSYRK + + G+
Sbjct: 482 TDYKIVMLGSGGVGKSSLTIRFTQDTFLDVYDPTIEDSYRKMIQVSGQ 625
>36482
          Length = 686

 Score = 84.7 bits (208), Expect = 2e-17,   Method: Compositional matrix adjust.
 Identities = 49/156 (31%), Positives = 85/156 (54%), Gaps = 4/156 (2%)
 Frame = +2

Query: 19  LTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGF 78
           LT++ +   F+ EY PT+E  Y+   VI+ +   L+ILDTAGQ  Y   ++ Y    + F
Sbjct: 2   LTVRFLTRRFIGEYCPTLESVYKYHTVIEDDDVRLEILDTAGQGTY-PWKEGYALWADCF 178

Query: 79  LCVFAINNSKSFADINLYREQIKRVKDSDDVPMVLVGNKCD-LPTRTVDTKQAHELAKSY 137
           + V++IN+ +S+ ++   + Q++ V+ S  +  VL  NK D L  R V  K+  +LA+  
Sbjct: 179 VFVYSINDRQSYEELVQVKRQVESVRKSTSLTAVLAANKTDLLHDRQVTQKEGEDLAEEI 358

Query: 138 GIPFIETSA---KTRQGVEDAFYTLVREIRQYRMKK 170
           G    E SA      + +   F+ L RE R+++ ++
Sbjct: 359 GCRLYEVSASEGSQMEAITSMFHDLYREFRKHKQQR 466
>14456
          Length = 1867

 Score = 84.3 bits (207), Expect = 3e-17,   Method: Compositional matrix adjust.
 Identities = 49/155 (31%), Positives = 85/155 (54%), Gaps = 5/155 (3%)
 Frame = -1

Query: 16   KSALTIQLIQNHFVDEYDPTIEDSY-RKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRT 74
            KS+L  + + N F  +   TI   +  K VV+D ET  + I DTAGQE + ++R  + R 
Sbjct: 1102 KSSLMNRFVSNKFDAQSFHTIGVEFLNKDVVVDDETYTMQIWDTAGQERFKSLRTPFYRG 923

Query: 75   GEGFLCVFAINNSKSFADINLYREQI---KRVKDSDDVPMVLVGNKCDLPTRTVDTKQAH 131
             +  L  F++++ +SF +++++R++      ++D    P V++GNK D+  R V  ++A 
Sbjct: 922  ADCCLLTFSVDSMQSFRNLSMWRKEFLYYADIQDGVTFPFVVLGNKIDVEGRQVTNEEAR 743

Query: 132  EL-AKSYGIPFIETSAKTRQGVEDAFYTLVREIRQ 165
                 +   P+ ETSAK    VE AF   V+ +R+
Sbjct: 742  SWCTANSNAPYFETSAKDATNVEKAFLAAVQRLRE 638
>06994
          Length = 429

 Score = 73.2 bits (178), Expect(2) = 4e-17,   Method: Compositional matrix adjust.
 Identities = 38/103 (36%), Positives = 53/103 (51%), Gaps = 32/103 (31%)
 Frame = +1

Query: 23  LIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAG---------------------- 60
           L +     +YDPTIEDSYRKQV +DG+ C+L+ILDTAG                      
Sbjct: 115 LCKGFLWKKYDPTIEDSYRKQVEVDGQQCMLEILDTAGTVHASHSNACVHGSLHAFVGTV 294

Query: 61  ----------QEEYSAMRDQYMRTGEGFLCVFAINNSKSFADI 93
                      E+++AMRD YM+ G+GFL  ++I    +F D+
Sbjct: 295 TPLGRDALLNTEQFTAMRDLYMKNGQGFLLAYSITAQSTFNDL 423

 Score = 31.2 bits (69), Expect(2) = 4e-17,   Method: Compositional matrix adjust.
 Identities = 14/31 (45%), Positives = 18/31 (58%)
 Frame = +3

Query: 1  MTEYKLXXXXXXXXXKSALTIQLIQNHFVDE 31
          M EYKL         KSALT+Q +Q  FV++
Sbjct: 48 MREYKLVVLGSGGVGKSALTVQFVQGIFVEK 140
>08428
          Length = 1109

 Score = 75.9 bits (185), Expect = 1e-14,   Method: Compositional matrix adjust.
 Identities = 46/150 (30%), Positives = 76/150 (50%), Gaps = 2/150 (1%)
 Frame = -3

Query: 16   KSALTIQLIQNHFVDEYDPTIEDSY-RKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRT 74
            KS++ ++ +   +    + TI  S+  K +V+DG      I DTAGQE++ A+   Y R 
Sbjct: 1032 KSSIVLRFVTGSYRPSQESTIGASFMSKSLVVDGAGYRFQIWDTAGQEKFRALAPMYYRG 853

Query: 75   GEGFLCVFAINNSKSFADINLYREQIKRVKDSDDVPMVLVGNKCDLPT-RTVDTKQAHEL 133
                + V+ +   ++F  +  + ++++     + V + + GNKCDL   R V  K A E 
Sbjct: 852  AAAAVIVYDVTRPRTFKSVKSWIQELRSFGPPNIV-LAIAGNKCDLEELREVVEKDAQEY 676

Query: 134  AKSYGIPFIETSAKTRQGVEDAFYTLVREI 163
            A S    F ETSA T   VE+ F  L R++
Sbjct: 675  ASSISAIFGETSAMTAVNVEEMFTELARQL 586
>34468
          Length = 1502

 Score = 74.3 bits (181), Expect = 3e-14,   Method: Compositional matrix adjust.
 Identities = 48/155 (30%), Positives = 79/155 (50%), Gaps = 6/155 (3%)
 Frame = +1

Query: 16  KSALTIQLIQNHFVDEYDPTIEDSYR-KQVVIDGETCLLDILDTAGQEEY-SAMRDQYMR 73
           K+ LT +     F D+ + TI   +R K + +D E   L + DTAGQE +  +M   Y R
Sbjct: 532 KTCLTYRFCLGKFPDKTEATIGVDFREKSIQVDSEHLKLQLWDTAGQERFRKSMVQHYYR 711

Query: 74  TGEGFLCVFAINNSKSFADINLYREQIKRVKDSDDVPMVLVGNKCDLPTR-TVDTKQAHE 132
                + V+ +    SF ++  + E+  R   +  +P +LVGNKCD+  R  V+T  A +
Sbjct: 712 NVHAVVFVYDMTKMSSFENMPAWIEECDRHNLTKYIPRILVGNKCDVVERIAVNTNLAQK 891

Query: 133 LAKSYGIPFIETSAK---TRQGVEDAFYTLVREIR 164
            A ++ +P  ETSAK       V+  F T+  +++
Sbjct: 892 FADAHNMPLFETSAKDDEKANHVDAIFMTVAHKLK 996
>33374
          Length = 489

 Score = 68.2 bits (165), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 38/112 (33%), Positives = 61/112 (54%), Gaps = 1/112 (0%)
 Frame = +1

Query: 44  VVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNSKSFADINLYREQIKRV 103
           V +D  T   +I DTAGQE Y ++   Y R  +  + V+ I N  +F     + ++++R 
Sbjct: 154 VCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNQDTFGRAKTWVKELQR- 330

Query: 104 KDSDDVPMVLVGNKCDLPT-RTVDTKQAHELAKSYGIPFIETSAKTRQGVED 154
           + S ++ + L GNK DL   R V+ ++A   A+   + F+ETSAKT   V D
Sbjct: 331 QASPNIVIALAGNKADLANKRMVEFEEAQAYAEENSLLFMETSAKTAMNVND 486
>11728
          Length = 635

 Score = 62.0 bits (149), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 45/153 (29%), Positives = 71/153 (46%), Gaps = 16/153 (10%)
 Frame = -1

Query: 16  KSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTG 75
           K+ L I    N F  EY PT+ D+Y   V++D +   L + DTAGQE+Y  +R       
Sbjct: 452 KTCLLISYTTNAFPGEYIPTVFDNYSANVMVDSKPINLGLWDTAGQEDYDRLRPLSYPQT 273

Query: 76  EGFLCVFAINNSKSFADI--NLYREQIKRVKDSDDVPMVLVGNKCDL------------- 120
           + FL  F++ +  SF ++    Y E      ++   P++LVG K DL             
Sbjct: 272 DVFLICFSLISPASFENVKAKWYPEVSHHCPNT---PIILVGTKLDLREDKETIEKLKEK 102

Query: 121 PTRTVDTKQAHELAKSYGI-PFIETSAKTRQGV 152
               +   Q   +AK  G   ++E SA T++G+
Sbjct: 101 KLAPITYPQGLAMAKDIGAGKYLECSALTQKGL 3
>07465
          Length = 1103

 Score = 62.0 bits (149), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 41/135 (30%), Positives = 67/135 (49%), Gaps = 2/135 (1%)
 Frame = +3

Query: 28  FVDEYDPTIE-DSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINN 86
           F  +Y  TI  D   +Q+ + GE   L + DTAGQEE+ A+   Y R  +  +  F+  +
Sbjct: 273 FTKDYKKTIGVDFLERQIEVGGEDVRLMLWDTAGQEEFDAITKAYYRGAQACVLAFSTVD 452

Query: 87  SKSFADINLYREQIKRVKDSDDVPMVLVGNKCDL-PTRTVDTKQAHELAKSYGIPFIETS 145
             SF  +  ++ +++   +  ++ MV+V NK DL     V  ++A  LAK   + F  TS
Sbjct: 453 RDSFEALETWKRKVE--DEVGEIGMVIVQNKIDLIDDAVVRPEEAENLAKKLRLRFYRTS 626

Query: 146 AKTRQGVEDAFYTLV 160
            K    V++ F  L 
Sbjct: 627 VKENMNVDEVFRYLA 671
>01972
          Length = 2359

 Score = 58.5 bits (140), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 31/111 (27%), Positives = 59/111 (53%)
 Frame = +3

Query: 53  LDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNSKSFADINLYREQIKRVKDSDDVPMV 112
            ++ DTAGQE++  +RD Y   G+  + +F + +  ++ ++  +   + RV   +++P+V
Sbjct: 453 FNVWDTAGQEKFGGLRDGYYIQGQCAVIMFDVTSRVTYKNVPNWHRDLVRV--CENIPIV 626

Query: 113 LVGNKCDLPTRTVDTKQAHELAKSYGIPFIETSAKTRQGVEDAFYTLVREI 163
           L GNK D+  R V  K A    +   + + + SAK+    E  F  L R++
Sbjct: 627 LCGNKVDIKDRKVKAK-AIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKL 776
>19656
          Length = 428

 Score = 57.8 bits (138), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 29/78 (37%), Positives = 42/78 (53%)
 Frame = +3

Query: 16  KSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTG 75
           K+ L I    N F  EY PT+ D+Y   V++DG    L + DTAGQE+Y  +R       
Sbjct: 150 KTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGRPVNLGLWDTAGQEDYDRLRPLSYPQT 329

Query: 76  EGFLCVFAINNSKSFADI 93
           + FL  F++ +  SF +I
Sbjct: 330 DVFLLCFSVASPASFENI 383
>17511
          Length = 483

 Score = 57.8 bits (138), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 31/109 (28%), Positives = 58/109 (53%), Gaps = 4/109 (3%)
 Frame = -3

Query: 16  KSALTIQLIQNHFVDEYDPTI-EDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRT 74
           K++L  Q +   F ++Y  TI  D   K+V++D     + I DTAGQE + ++   + R 
Sbjct: 328 KTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQIWDTAGQERFQSLGVAFYRG 149

Query: 75  GEGFLCVFAINNSKSFADINLYREQI---KRVKDSDDVPMVLVGNKCDL 120
            +  + VF +    +F  ++ +R++       +D ++ P V++GNK DL
Sbjct: 148 ADCCVLVFDVTMPNTFRSLDSWRDEFLIQASPRDPENFPFVVIGNKIDL 2
>13745
          Length = 1045

 Score = 57.0 bits (136), Expect = 5e-09,   Method: Compositional matrix adjust.
 Identities = 32/105 (30%), Positives = 57/105 (54%), Gaps = 4/105 (3%)
 Frame = +2

Query: 61  QEEYSAMRDQYMRTGEGFLCVFAINNSKSFADINLYREQI---KRVKDSDDVPMVLVGNK 117
           QE + ++   + R  +  + V+ +    SF +++ +R++       +D +  P V++GNK
Sbjct: 2   QERFQSLGVAFYRGADCCVLVYDVTAPNSFKNLDSWRDEFLIQASPRDPEHFPFVVLGNK 181

Query: 118 CDLPTRTVDTKQAHELAKSYG-IPFIETSAKTRQGVEDAFYTLVR 161
            DL  R V T++A +  +S   IP+ ETSAK    VE AF T+ +
Sbjct: 182 VDLDNRQVSTRRAQQWCQSKNDIPYYETSAKEGINVEMAFQTIAK 316
>33380
          Length = 282

 Score = 56.6 bits (135), Expect = 6e-09,   Method: Compositional matrix adjust.
 Identities = 29/68 (42%), Positives = 39/68 (57%)
 Frame = +3

Query: 53  LDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNSKSFADINLYREQIKRVKDSDDVPMV 112
           L I DTAGQE Y  +   Y R   GF+ ++ + N +SF  +  +  QIK     D+  +V
Sbjct: 66  LQIWDTAGQERYRTITTAYYRGAMGFILMYDVTNEESFNAVQDWCTQIK-TYSWDNAQVV 242

Query: 113 LVGNKCDL 120
           LVGNKCDL
Sbjct: 243 LVGNKCDL 266
>12339
          Length = 578

 Score = 54.3 bits (129), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 32/105 (30%), Positives = 55/105 (52%), Gaps = 4/105 (3%)
 Frame = -2

Query: 61  QEEYSAMRDQYMRTGEGFLCVFAINNSKSFADINLY-REQIKRV--KDSDDVPMVLVGNK 117
           QE + ++   + R  +  + V+ +   K+F  ++ + RE + +   +D +  P V++GNK
Sbjct: 577 QERFQSLGVAFYRGADCCILVYDVTEXKTFDSLDSWQREFLNQASPRDPEHFPFVVIGNK 398

Query: 118 CDLPTRTVDTKQAHELAKSYG-IPFIETSAKTRQGVEDAFYTLVR 161
            DL  R V  K+      + G IP+ ETSAK    VE AF T+ +
Sbjct: 397 IDLDNRVVTAKRGQGWCSTKGGIPYFETSAKEAINVEQAFQTVAK 263
>19006
          Length = 568

 Score = 53.5 bits (127), Expect = 5e-08,   Method: Compositional matrix adjust.
 Identities = 32/106 (30%), Positives = 57/106 (53%), Gaps = 1/106 (0%)
 Frame = -2

Query: 16  KSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTG 75
           K+ L I   ++ F + Y PT+ ++Y   + +D +   L + DTAGQE+Y  +R       
Sbjct: 399 KTCLLIVFSKDQFPEVYVPTVFENYVADIEVDSKQVELALWDTAGQEDYDRLRPLSYPDT 220

Query: 76  EGFLCVFAINNSKSFADI-NLYREQIKRVKDSDDVPMVLVGNKCDL 120
           +  L  F+I++  S  +I   +  +++      +VP++LVGNK DL
Sbjct: 219 DVILMCFSIDSPDSLENIPEKWTPEVRHF--CPNVPIILVGNKKDL 88
>01398
          Length = 1421

 Score = 53.5 bits (127), Expect = 5e-08,   Method: Compositional matrix adjust.
 Identities = 30/129 (23%), Positives = 59/129 (45%), Gaps = 4/129 (3%)
 Frame = -2

Query: 61   QEEYSAMRDQYMRTGEGFLCVFAINNSKSFADINLYREQIKRVKDSDDVPMVLVGNKCDL 120
            QE + ++   Y R   G + V+ I    +F ++  + E+ +   +      +++G+K D 
Sbjct: 1420 QERFRSITRSYYRNSVGVIIVYDITKRSTFENLKQWYEEARNHIEPHKAIFLVLGHKSDR 1241

Query: 121  P-TRTVDTKQAHELAKSYGIPFIETSAKTRQGVEDAFYTLVREIRQYRMK---KLNSSDD 176
               R V  ++    A+ +G+ F ETSAK+   +ED F  + ++  Q+      +L    D
Sbjct: 1240 EDARQVTAREGRRFAEMHGLKFFETSAKSGHNIEDVFAQIAKDTYQHLQDGHIRLEEGWD 1061

Query: 177  GTQGCMGLP 185
            G +     P
Sbjct: 1060 GVKQGFARP 1034
>26083
          Length = 432

 Score = 51.6 bits (122), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 33/118 (27%), Positives = 60/118 (50%), Gaps = 1/118 (0%)
 Frame = +1

Query: 1   MTEYKLXXXXXXXXXKSALTIQLIQNHFVDEYDPTIE-DSYRKQVVIDGETCLLDILDTA 59
           + ++KL         K++L  + + + F + Y  TI  D   K + ++  T  L + DTA
Sbjct: 70  LRKFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTIRLQLWDTA 249

Query: 60  GQEEYSAMRDQYMRTGEGFLCVFAINNSKSFADINLYREQIKRVKDSDDVPMVLVGNK 117
           GQE + ++   Y+R     + V+ I N+ SF   + + + + R +   DV ++LVGNK
Sbjct: 250 GQERFRSLIPSYIRDSSVAVVVYDITNANSFHQTSKWIDDV-RTERGSDVIIMLVGNK 420
>34359
          Length = 1042

 Score = 51.2 bits (121), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 27/111 (24%), Positives = 57/111 (51%), Gaps = 6/111 (5%)
 Frame = +3

Query: 53  LDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNSKSFADINLYREQIKRVKDSDDVPMV 112
            ++ DTAGQE++  +RD Y   G   + +F + +  ++ ++  +   + RV   +++P+V
Sbjct: 201 FNVWDTAGQEKFGGLRDGYYIQGTCAIIMFDVTSRVTYKNVPNWHRDLVRV--CENIPIV 374

Query: 113 LVGNKCDLPTRTVDTK-----QAHELAKSYGIPFIETSAKTRQ-GVEDAFY 157
           L GNK D+  R V  K     +    + +  +P   T+ ++R  G   +++
Sbjct: 375 LCGNKVDIKDRKVKAKAIVFHRKRTCSTTTSVPRATTTLRSRSCGWRASWW 527
>34597
          Length = 773

 Score = 47.8 bits (112), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 29/85 (34%), Positives = 47/85 (55%), Gaps = 1/85 (1%)
 Frame = -2

Query: 80  CVFAINNSKSFADINLYREQIKRVKDSDDVPMVLVGNKCDLPTRTVDTKQAHE-LAKSYG 138
           C+      KSF +I  +   I     ++DV  +++GNKCD+  + V +K+  E +A+ + 
Sbjct: 736 CLMT*RMKKSFENIVKWLRNIDE-HANEDVEKMILGNKCDMTDKRVVSKERGEAIAREHS 560

Query: 139 IPFIETSAKTRQGVEDAFYTLVREI 163
           I F+ETSAK+   +E AF  L   I
Sbjct: 559 IRFMETSAKSNINIERAFCELAEAI 485
>01095
          Length = 1745

 Score = 46.6 bits (109), Expect = 7e-06,   Method: Compositional matrix adjust.
 Identities = 26/85 (30%), Positives = 47/85 (55%), Gaps = 1/85 (1%)
 Frame = -1

Query: 80   CVFAINNSKSFADINLYREQIKRVKDSDDVPMVLVGNKCDLPT-RTVDTKQAHELAKSYG 138
             V+ I N  +F     + ++++R + S ++ + L GNK DL   R V+ ++A   A+   
Sbjct: 1745 VVYDITNQDTFGRAKTWVKELQR-QASPNIVIALAGNKADLANKRMVEFEEAQAYAEENS 1569

Query: 139  IPFIETSAKTRQGVEDAFYTLVREI 163
            + F+ETSAKT   V D F  + +++
Sbjct: 1568 LLFMETSAKTAMNVNDIFLAIAKKL 1494
>32723
          Length = 384

 Score = 46.2 bits (108), Expect = 7e-06,   Method: Compositional matrix adjust.
 Identities = 34/125 (27%), Positives = 59/125 (47%), Gaps = 1/125 (0%)
 Frame = +2

Query: 61  QEEYSAMRDQYMRTGEGFLCVFAINNSKSFADINLYREQIKRVKDSDDVPMVLVGNKCDL 120
           QE + ++   Y R+    + V+ + + +S+  +  +  +I+ +     V   LVGNK D 
Sbjct: 2   QERFRSITQSYYRSANALILVYDVCSQQSYESLPQWIHEIE-LYAGTKVLAFLVGNKIDQ 178

Query: 121 P-TRTVDTKQAHELAKSYGIPFIETSAKTRQGVEDAFYTLVREIRQYRMKKLNSSDDGTQ 179
              R + T    E A+ Y + F+ETSAK    VE  F T+  ++       L  ++  TQ
Sbjct: 179 TDKREIPTHIGKEFAERYEMRFLETSAKEADNVEKLFSTIAYQLTAQAQGTLG-AEA*TQ 355

Query: 180 GCMGL 184
           G + L
Sbjct: 356 GPLSL 370
>31291
          Length = 446

 Score = 46.2 bits (108), Expect = 7e-06,   Method: Compositional matrix adjust.
 Identities = 37/123 (30%), Positives = 60/123 (48%), Gaps = 14/123 (11%)
 Frame = -1

Query: 53  LDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNSKSFADINLYREQIKRVKDSDDVPMV 112
           L + DTAGQE+Y  +R       + F+  F++ +  S  ++ +      R  D   VP+V
Sbjct: 446 LQLWDTAGQEDYDRLRPLAYPNTDVFMLXFSLMSEASMKNVKVKWYPEIRHHDP-HVPIV 270

Query: 113 LVGNKCDL-----------PTR--TVDTKQAHELAKSYGIP-FIETSAKTRQGVEDAFYT 158
           LVG K DL            +R   V + Q ++LAK+     + E S+KT++ ++ AF  
Sbjct: 269 LVGTKLDLRQDKEAVRKLRSSRQDPVSSNQGNDLAKAIKAKRYFECSSKTQENLKTAFEE 90

Query: 159 LVR 161
            VR
Sbjct: 89  TVR 81
>25655
          Length = 871

 Score = 33.5 bits (75), Expect(2) = 9e-06,   Method: Compositional matrix adjust.
 Identities = 13/20 (65%), Positives = 17/20 (85%)
 Frame = -3

Query: 132 ELAKSYGIPFIETSAKTRQG 151
            +A+ Y IP++ETSAKTRQG
Sbjct: 866 HMAELYHIPYVETSAKTRQG 807

 Score = 32.0 bits (71), Expect(2) = 9e-06,   Method: Compositional matrix adjust.
 Identities = 13/16 (81%), Positives = 16/16 (100%)
 Frame = -2

Query: 152 VEDAFYTLVREIRQYR 167
           V+DAFYTLVREIR+Y+
Sbjct: 807 VDDAFYTLVREIRKYK 760
>31928
          Length = 429

 Score = 35.0 bits (79), Expect = 0.019,   Method: Compositional matrix adjust.
 Identities = 24/87 (27%), Positives = 43/87 (49%), Gaps = 4/87 (4%)
 Frame = +2

Query: 35  TIEDSYRKQVVID-GETCLLDILDTAGQEEYSAMRD---QYMRTGEGFLCVFAINNSKSF 90
           TIED Y   +  D G    + I DT      +   D    Y+   +GF+ V+   + +SF
Sbjct: 53  TIEDIYTAVIETDRGVKEKVRIFDTGAAALETTEGDLPKHYLNFPDGFVLVYDTTSWESF 232

Query: 91  ADINLYREQIKRVKDSDDVPMVLVGNK 117
             ++  ++ I + +D  +V M+++GNK
Sbjct: 233 RRLDKLKKDIDKHRDKREVHMIVIGNK 313
>00552
          Length = 455

 Score = 34.7 bits (78), Expect = 0.023,   Method: Compositional matrix adjust.
 Identities = 15/46 (32%), Positives = 27/46 (58%)
 Frame = -3

Query: 55  ILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNSKSFADINLYREQI 100
           I DTAGQE Y ++R  + R  +  L  F+++N KS   ++ + ++ 
Sbjct: 147 IWDTAGQERYKSLRTPFYRGTDCCLLTFSVDNLKSLQSLSDWYDEF 10
>21396
          Length = 647

 Score = 32.3 bits (72), Expect = 0.12,   Method: Compositional matrix adjust.
 Identities = 15/42 (35%), Positives = 21/42 (50%)
 Frame = -2

Query: 28  FVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRD 69
           F +E  PT       Q +  G  CLL +L T+  E +S +RD
Sbjct: 388 FFEELRPTTSHHDHTQSLFHGRLCLLFLLCTSALEIHSFLRD 263
>35581
          Length = 364

 Score = 30.4 bits (67), Expect = 0.48,   Method: Compositional matrix adjust.
 Identities = 12/30 (40%), Positives = 18/30 (60%)
 Frame = +2

Query: 53  LDILDTAGQEEYSAMRDQYMRTGEGFLCVF 82
           +D+ DTAGQE Y ++   Y R  +  L V+
Sbjct: 200 VDLWDTAGQERYRSLTSSYYRDTKAVLIVY 289
>10708
          Length = 2775

 Score = 28.1 bits (61), Expect = 2.3,   Method: Compositional matrix adjust.
 Identities = 14/41 (34%), Positives = 22/41 (53%)
 Frame = -2

Query: 53   LDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNSKSFADI 93
            L + DTAGQE+Y  +R       +  L  F+I++  S  +I
Sbjct: 2717 LALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENI 2595
>09309
          Length = 1508

 Score = 27.7 bits (60), Expect = 2.9,   Method: Compositional matrix adjust.
 Identities = 11/32 (34%), Positives = 20/32 (62%)
 Frame = +3

Query: 102 RVKDSDDVPMVLVGNKCDLPTRTVDTKQAHEL 133
           R+++ +  P  +   +  LPT + DT+QAHE+
Sbjct: 258 RIEEPESRPAPVTSKESVLPTGSGDTQQAHEM 353
>18949
          Length = 414

 Score = 26.9 bits (58), Expect = 4.9,   Method: Compositional matrix adjust.
 Identities = 16/79 (20%), Positives = 35/79 (44%), Gaps = 4/79 (5%)
 Frame = +3

Query: 56  LDTAGQEEYSAMRDQYMRTGEGFLCVFAINNSKSFADINLYREQIKRVKDSDDVPMVLVG 115
            D  G  +   +   Y    +G + +  +++++   +     + + R     D+P++++G
Sbjct: 72  FDLGGHRQARRVWKDYFPAVDGIVFIVDVHDTERITEAKAELDSLLRDDQIADIPVLVLG 251

Query: 116 NKCD----LPTRTVDTKQA 130
           NK D    +  RT DT  A
Sbjct: 252 NKMDKHGVVERRTSDTGWA 308
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|15277319|ref|NP_201579.1| leucine zipper
transcription factor-like 1 [Mus musculus]
         (299 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

08389                                                                 251   6e-69
22980                                                                  29   2.7  
>08389
          Length = 962

 Score =  251 bits (641), Expect(2) = 6e-69,   Method: Compositional matrix adjust.
 Identities = 138/281 (49%), Positives = 182/281 (64%)
 Frame = +1

Query: 19  RFARSKRGLRLKTVDSCFQDLKDSRLVEETFTIDEVSEVLNGLQAVVHSEVESELINTAY 78
           RFAR +RG RL+ VD CF++LKDSRL +ETFTIDEV+E+L+GL  VV SEVESELINTA+
Sbjct: 85  RFARYQRGQRLRAVDLCFEELKDSRLTDETFTIDEVTEMLDGLLTVVRSEVESELINTAH 264

Query: 79  TNVLLLRQLFSQAEKWYLKLQTDISELENRELLEQVAEFEKAEFVSSSKKPIIDITKPKL 138
           TNVL++RQ+F QAEKW+LKLQ DISELENRELLEQ+ EFE+ EF  + +    +     L
Sbjct: 265 TNVLMMRQMFQQAEKWHLKLQADISELENRELLEQIKEFEEREFAGAKRD--TEFVPKML 438

Query: 139 VPINEGGTTELLNKEILRLQQENEKLKSRLKTIEIQAVNALDEKSKLERVXXXXXXXXXX 198
            P+NE G T LL+ +I  LQ +NEK+K+ L  ++      +  +  L             
Sbjct: 439 EPVNETGGTALLHMKIEELQAQNEKMKAHLMKVDKNFAMMMASQGSL---SSELELAKGA 609

Query: 199 XXXXXXXXXXXXXENTVATLRSEFQKTLNDKTENQKSLEENLAAAKHDLLRVQEQLSMAE 258
                          T+A L S+ +          +  E++L++ KH+LL+++E L +AE
Sbjct: 610 LGRASNDGDVESLRKTMAGLESQIESERAKGRMTAEGAEKDLSSTKHELLKIREMLELAE 789

Query: 259 KELEKKFQQTAAYRNMKEILTKKNDQIKDLRKRLAKYESED 299
           KELEKK   TA +RN+K +L KKNDQIKDLRKRL KYES D
Sbjct: 790 KELEKKVSMTAPFRNLKSMLQKKNDQIKDLRKRLGKYESLD 912

 Score = 27.3 bits (59), Expect(2) = 6e-69,   Method: Compositional matrix adjust.
 Identities = 10/13 (76%), Positives = 13/13 (100%)
 Frame = +2

Query: 6  LNEHHQNEVINYM 18
          +NEHHQN+VINY+
Sbjct: 47 VNEHHQNQVINYI 85
>22980
          Length = 1128

 Score = 28.9 bits (63), Expect = 2.7,   Method: Compositional matrix adjust.
 Identities = 17/45 (37%), Positives = 26/45 (57%)
 Frame = -3

Query: 121 EFVSSSKKPIIDITKPKLVPINEGGTTELLNKEILRLQQENEKLK 165
           +F+S+++KP+  I  PKL  I E  TTE +   I  LQ   + L+
Sbjct: 832 QFISNTQKPLTSIHTPKL--ITEKTTTENIYIIICTLQIPTQSLR 704
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|22122795|ref|NP_666341.1| dynein cytoplasmic 1 light
intermediate chain 1 [Mus musculus]
         (523 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

06254                                                                 248   6e-69
26083                                                                  32   0.59 
05468                                                                  31   1.4  
07465                                                                  28   8.8  
>06254
          Length = 2204

 Score =  248 bits (634), Expect(2) = 6e-69,   Method: Compositional matrix adjust.
 Identities = 118/215 (54%), Positives = 161/215 (74%), Gaps = 7/215 (3%)
 Frame = +2

Query: 179 PPEEMKEMEQKLIRDFQEYVEP--GEDFPASPQRRTTG----AQEDRGDSVVLPLGADTL 232
           P ++M++ EQ L+R FQ+Y  P  G+    +P R        A     D VVLPLG + L
Sbjct: 215 PQKKMRDYEQSLVRFFQDYTAPEEGQSSSQAPPRGDANPLHPALMTDDDKVVLPLGDNVL 394

Query: 233 THNLGLPVLVVCTKCDAISVLEKEHDYRDEHFDFIQSHIRKFCLQYGAALIYTSVKENKN 292
           THNLG+PV+VV TKCDAIS LEK+HD+R+EHFDFIQ ++RKFCL+YGA L YTSVK+ +N
Sbjct: 395 THNLGIPVVVVLTKCDAISSLEKDHDFREEHFDFIQQYVRKFCLKYGAGLFYTSVKDERN 574

Query: 293 IDLVYKYIVQKLYGFPYKIPAVVVEKDAVFIPAGWDNDKKIGILHENFQTLKVEDNFEDI 352
            +L+Y+Y+V ++YGFP+  PA VV++D+VF+P GWDN+KKI IL+EN  ++K ED  ED+
Sbjct: 575 CELLYRYLVHRIYGFPFTTPAYVVDRDSVFVPCGWDNEKKISILYENMSSVKPEDGLEDV 754

Query: 353 ITKPPVRKFVH-EKEIMAEDDQVFLMKLQSLLAKQ 386
           I +P +RK V  + E+ AED+QV+LMKLQ++LAKQ
Sbjct: 755 IVRPVLRKPVQRDAEVFAEDEQVYLMKLQAVLAKQ 859

 Score = 31.2 bits (69), Expect(2) = 6e-69,   Method: Compositional matrix adjust.
 Identities = 17/30 (56%), Positives = 20/30 (66%), Gaps = 4/30 (13%)
 Frame = +1

Query: 427 SKKIDPNMKAGAT----SEGVLANFFNSLL 452
           S K   + KAG T    +EG+LANFFNSLL
Sbjct: 964 SPKCGKDPKAGGTPGQATEGMLANFFNSLL 1053

 Score = 59.7 bits (143), Expect(2) = 4e-15,   Method: Compositional matrix adjust.
 Identities = 24/51 (47%), Positives = 38/51 (74%)
 Frame = +1

Query: 140 SLRDTLVMLVVDMSKPWTALDSLQKWASVVREHVDKLKIPPEEMKEMEQKL 190
           +  D++VMLV  M++PW+  DSL KW +V+ +H+DKL+IPPE+ + +  KL
Sbjct: 97  TFEDSMVMLVASMAQPWSIADSLTKWITVLSQHIDKLRIPPEKNERLXTKL 249

 Score = 39.7 bits (91), Expect(2) = 4e-15,   Method: Compositional matrix adjust.
 Identities = 15/26 (57%), Positives = 20/26 (76%)
 Frame = +3

Query: 111 RDDQTRCNVWILDGDLYHKGLLKFSL 136
           RD+Q R NVW+LDGD  H  L+K++L
Sbjct: 9   RDEQARLNVWVLDGDQSHTALMKYAL 86
>26083
          Length = 432

 Score = 32.0 bits (71), Expect = 0.59,   Method: Composition-based stats.
 Identities = 29/104 (27%), Positives = 44/104 (42%), Gaps = 3/104 (2%)
 Frame = +1

Query: 70  VLLLGEDGAGKTSLIRRI---QGIEEYKKGRGLEYLYLNVHDEDRDDQTRCNVWILDGDL 126
           ++ LGE   GKTSLI R         Y+   G+++L   ++ EDR    R  +W   G  
Sbjct: 85  LVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDR--TIRLQLWDTAGQE 258

Query: 127 YHKGLLKFSLDALSLRDTLVMLVVDMSKPWTALDSLQKWASVVR 170
             + L+        +RD+ V +VV       +     KW   VR
Sbjct: 259 RFRSLI-----PSYIRDSSVAVVVYDITNANSFHQTSKWIDDVR 375
>05468
          Length = 1558

 Score = 30.8 bits (68), Expect = 1.4,   Method: Compositional matrix adjust.
 Identities = 25/100 (25%), Positives = 50/100 (50%), Gaps = 4/100 (4%)
 Frame = -3

Query: 70   VLLLGEDGAGKTSLIRRIQG---IEEYKKGRGLEYLYLNVHDEDRDDQTRCNVWILDGDL 126
            +L++GE G GKTS+I+R       + Y+   G+++  L V + D D   R  +W + G  
Sbjct: 1532 ILVIGELGTGKTSIIKRYVHQFFSQHYRATIGVDFA-LKVLNWDADTLIRLQLWDIAGQE 1356

Query: 127  YHKGLLK-FSLDALSLRDTLVMLVVDMSKPWTALDSLQKW 165
                + + +  +A+        +V D+++  +  D++ KW
Sbjct: 1355 RFGNMTRVYYKEAVG-----AFVVFDVTRA-STFDAVTKW 1254
>07465
          Length = 1103

 Score = 28.1 bits (61), Expect = 8.8,   Method: Compositional matrix adjust.
 Identities = 11/19 (57%), Positives = 15/19 (78%)
 Frame = +3

Query: 285 TSVKENKNIDLVYKYIVQK 303
           TSVKEN N+D V++Y+  K
Sbjct: 621 TSVKENMNVDEVFRYLADK 677
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|84370270|ref|NP_067259.3| c-K-ras2 protein [Mus
musculus]
         (188 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

00858                                                                 255   8e-69
07580                                                                 168   6e-45
18509                                                                  98   1e-30
19046                                                                 100   4e-22
24619                                                                  98   2e-21
11257                                                                  94   4e-20
26536                                                                  87   4e-18
36482                                                                  87   5e-18
06994                                                                  74   2e-17
14456                                                                  82   1e-16
08428                                                                  79   2e-15
34468                                                                  78   2e-15
33374                                                                  67   5e-12
07465                                                                  65   2e-11
11728                                                                  64   4e-11
17511                                                                  62   2e-10
01972                                                                  61   3e-10
13745                                                                  61   3e-10
19656                                                                  60   4e-10
12339                                                                  59   1e-09
33380                                                                  58   2e-09
19006                                                                  57   6e-09
34359                                                                  53   6e-08
26083                                                                  53   8e-08
34597                                                                  53   8e-08
32723                                                                  48   2e-06
01095                                                                  45   2e-05
31291                                                                  45   2e-05
25655                                                                  33   4e-05
00552                                                                  37   0.004
31928                                                                  34   0.044
21396                                                                  32   0.17 
09700                                                                  31   0.32 
10708                                                                  30   0.42 
35581                                                                  30   0.62 
27191                                                                  27   7.0  
>00858
          Length = 1658

 Score =  255 bits (651), Expect = 8e-69,   Method: Compositional matrix adjust.
 Identities = 124/163 (76%), Positives = 136/163 (83%)
 Frame = -2

Query: 1    MTEYKLXXXXXXXXXKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAG 60
            MTEYKL         KSALTIQL QNHFV+EYDPT EDS RKQVVIDGETCLLDILDTAG
Sbjct: 1597 MTEYKLVVVGAGGVGKSALTIQLXQNHFVEEYDPTXEDSXRKQVVIDGETCLLDILDTAG 1418

Query: 61   QEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKSVKDSEDVPMVLVGNKCDL 120
            QEE SAMRDQ MRTGEGFLCVFA+ N KSFEDI+ YREQIK VKD+++VPMVLVGNK DL
Sbjct: 1417 QEEXSAMRDQCMRTGEGFLCVFAVXNLKSFEDINQYREQIKRVKDADEVPMVLVGNKVDL 1238

Query: 121  PSRTVDTKQAQELARSYGIPFIETSAKTRQGVDDAFYTLVREI 163
            P R V+ +Q + +A  Y IP++ETSAKTRQGVDDAFYTLVREI
Sbjct: 1237 PIRNVEQRQGKHMAELYHIPYVETSAKTRQGVDDAFYTLVREI 1109
>07580
          Length = 921

 Score =  168 bits (425), Expect(2) = 6e-45,   Method: Compositional matrix adjust.
 Identities = 80/142 (56%), Positives = 104/142 (73%), Gaps = 1/142 (0%)
 Frame = +3

Query: 23  LIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVF 82
           L +  FV++YDPTIEDSYRKQV +DG+ C+L+ILDTAG E+++AMRD YM+ G+GFL  +
Sbjct: 120 LCKGIFVEKYDPTIEDSYRKQVEVDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFLLAY 299

Query: 83  AINNTKSFEDIHHYREQIKSVKDSEDVPMVLVGNKCDLP-SRTVDTKQAQELARSYGIPF 141
           +I    +F D+   REQI  VKD++DVPM+LVGNKCDL   R V   Q Q LARS+   F
Sbjct: 300 SITAQSTFNDLQELREQILRVKDTDDVPMLLVGNKCDLEDERVVGKDQGQGLARSFSCAF 479

Query: 142 IETSAKTRQGVDDAFYTLVREI 163
           +ETSAK R  V++ F  LVR+I
Sbjct: 480 LETSAKARINVNEIFMDLVRQI 545

 Score = 29.3 bits (64), Expect(2) = 6e-45,   Method: Compositional matrix adjust.
 Identities = 13/28 (46%), Positives = 15/28 (53%)
 Frame = +2

Query: 1  MTEYKLXXXXXXXXXKSALTIQLIQNHF 28
          M EYKL         KSALT+Q +Q  F
Sbjct: 53 MREYKLVVLGSGGVGKSALTVQFVQGDF 136
>18509
          Length = 625

 Score = 97.8 bits (242), Expect(2) = 1e-30,   Method: Compositional matrix adjust.
 Identities = 44/62 (70%), Positives = 53/62 (85%)
 Frame = -3

Query: 103 VKDSEDVPMVLVGNKCDLPSRTVDTKQAQELARSYGIPFIETSAKTRQGVDDAFYTLVRE 162
           VKD+++VPMVLVGNK DLP R V+ +Q + +A  Y IP++ETSAKTRQGVDDAFYTLVRE
Sbjct: 545 VKDADEVPMVLVGNKVDLPIRNVEQRQGKHMAELYHIPYVETSAKTRQGVDDAFYTLVRE 366

Query: 163 IR 164
           IR
Sbjct: 365 IR 360

 Score = 52.0 bits (123), Expect(2) = 1e-30,   Method: Compositional matrix adjust.
 Identities = 22/26 (84%), Positives = 24/26 (92%)
 Frame = -1

Query: 76  EGFLCVFAINNTKSFEDIHHYREQIK 101
           EGFLCVFA+NN KSFEDI+ YREQIK
Sbjct: 625 EGFLCVFAVNNLKSFEDINQYREQIK 548
>19046
          Length = 445

 Score =  100 bits (249), Expect = 4e-22,   Method: Compositional matrix adjust.
 Identities = 53/106 (50%), Positives = 72/106 (67%), Gaps = 2/106 (1%)
 Frame = -2

Query: 61  QEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKSVKDSEDVPMVLVGNKCDL 120
           QEE+SAMR+QYMR G+GFL VF++ + +SFE++ ++  QI  VKD +  PM+L  NK DL
Sbjct: 444 QEEFSAMREQYMRKGDGFLLVFSVTDFRSFENMANFHTQILRVKDRDSYPMILCANKVDL 265

Query: 121 -PSRTVDTKQAQELARSYGIPFIETSAKTRQ-GVDDAFYTLVREIR 164
              R V  +Q ++LA    IP+IETSAK     VD AF+ +VR IR
Sbjct: 264 VHQRKVSEEQVRDLATRLRIPYIETSAKDPPLNVDLAFHQVVRVIR 127
>24619
          Length = 509

 Score = 97.8 bits (242), Expect = 2e-21,   Method: Compositional matrix adjust.
 Identities = 53/106 (50%), Positives = 72/106 (67%), Gaps = 2/106 (1%)
 Frame = -2

Query: 61  QEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKSVKDSEDVPMVLVGNKCDL 120
           QEE+SAMR+QYMR G+GFL VF++ + +SFE++ ++  QI  VKD +  PM+L  NK DL
Sbjct: 508 QEEFSAMREQYMRKGDGFLLVFSVIDYQSFENMVNFHTQILRVKDRDTYPMILCANKVDL 329

Query: 121 -PSRTVDTKQAQELARSYGIPFIETSAK-TRQGVDDAFYTLVREIR 164
              R V  +Q ++LA    IP+IETSAK     VD AF+ +VR IR
Sbjct: 328 VHQRKVSEEQVRDLATRLRIPYIETSAKDPPLNVDLAFHQVVRVIR 191
>11257
          Length = 1102

 Score = 93.6 bits (231), Expect = 4e-20,   Method: Compositional matrix adjust.
 Identities = 47/127 (37%), Positives = 74/127 (58%), Gaps = 4/127 (3%)
 Frame = -2

Query: 42   KQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQI- 100
            K VV+DGET  + I DTAGQE Y ++R  + R  +  L  F+++N KS + +  + ++  
Sbjct: 1053 KDVVVDGETFTMQIWDTAGQERYKSLRTPFYRGTDCCLLTFSVDNLKSLQSLSDWYDEFV 874

Query: 101  --KSVKDSEDVPMVLVGNKCDLPSRTVDTKQAQELARSYG-IPFIETSAKTRQGVDDAFY 157
                ++DS   P V++GNK D+  R V ++ A    R++G +P+ ETSAK    V  AF 
Sbjct: 873  NYADIQDSASFPFVIIGNKADIEEREVSSEDAYNWCRTHGNLPYFETSAKDSLNVQQAFL 694

Query: 158  TLVREIR 164
             +VR +R
Sbjct: 693  AVVRRLR 673
>26536
          Length = 829

 Score = 86.7 bits (213), Expect(2) = 4e-18,   Method: Compositional matrix adjust.
 Identities = 43/110 (39%), Positives = 67/110 (60%), Gaps = 1/110 (0%)
 Frame = +2

Query: 55  ILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKSVKDSEDVPMVLV 114
            LDTAGQEEYS+MR+ Y R+G+GF+ V+++ +  SF++       +   +D   +  VL 
Sbjct: 140 FLDTAGQEEYSSMREHYTRSGDGFIVVYSVTDVTSFQEAEAVFRWLTRFQDETSIHAVLC 319

Query: 115 GNKCDLPS-RTVDTKQAQELARSYGIPFIETSAKTRQGVDDAFYTLVREI 163
           GNK DL S R V  ++ +++A   G+ + ETSAKT   V   ++ L+R I
Sbjct: 320 GNKTDLTSDRKVTPEEGRKMADRLGMLYFETSAKTGDNVSQVYHGLLRSI 469

 Score = 21.2 bits (43), Expect(2) = 4e-18,   Method: Compositional matrix adjust.
 Identities = 8/13 (61%), Positives = 8/13 (61%)
 Frame = +1

Query: 48  GETCLLDILDTAG 60
           GETC LDI    G
Sbjct: 118 GETCFLDIFGHRG 156

 Score = 51.6 bits (122), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 23/48 (47%), Positives = 32/48 (66%)
 Frame = +2

Query: 2   TEYKLXXXXXXXXXKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGE 49
           T+YK+         KS+LTI+  Q+ F+D YDPTIEDSYRK + + G+
Sbjct: 482 TDYKIVMLGSGGVGKSSLTIRFTQDTFLDVYDPTIEDSYRKMIQVSGQ 625
>36482
          Length = 686

 Score = 86.7 bits (213), Expect = 5e-18,   Method: Compositional matrix adjust.
 Identities = 51/150 (34%), Positives = 82/150 (54%), Gaps = 4/150 (2%)
 Frame = +2

Query: 19  LTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGF 78
           LT++ +   F+ EY PT+E  Y+   VI+ +   L+ILDTAGQ  Y   ++ Y    + F
Sbjct: 2   LTVRFLTRRFIGEYCPTLESVYKYHTVIEDDDVRLEILDTAGQGTY-PWKEGYALWADCF 178

Query: 79  LCVFAINNTKSFEDIHHYREQIKSVKDSEDVPMVLVGNKCD-LPSRTVDTKQAQELARSY 137
           + V++IN+ +S+E++   + Q++SV+ S  +  VL  NK D L  R V  K+ ++LA   
Sbjct: 179 VFVYSINDRQSYEELVQVKRQVESVRKSTSLTAVLAANKTDLLHDRQVTQKEGEDLAEEI 358

Query: 138 GIPFIETSA---KTRQGVDDAFYTLVREIR 164
           G    E SA      + +   F+ L RE R
Sbjct: 359 GCRLYEVSASEGSQMEAITSMFHDLYREFR 448
>06994
          Length = 429

 Score = 73.9 bits (180), Expect(2) = 2e-17,   Method: Compositional matrix adjust.
 Identities = 38/103 (36%), Positives = 53/103 (51%), Gaps = 32/103 (31%)
 Frame = +1

Query: 23  LIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAG---------------------- 60
           L +     +YDPTIEDSYRKQV +DG+ C+L+ILDTAG                      
Sbjct: 115 LCKGFLWKKYDPTIEDSYRKQVEVDGQQCMLEILDTAGTVHASHSNACVHGSLHAFVGTV 294

Query: 61  ----------QEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDI 93
                      E+++AMRD YM+ G+GFL  ++I    +F D+
Sbjct: 295 TPLGRDALLNTEQFTAMRDLYMKNGQGFLLAYSITAQSTFNDL 423

 Score = 31.2 bits (69), Expect(2) = 2e-17,   Method: Compositional matrix adjust.
 Identities = 14/31 (45%), Positives = 18/31 (58%)
 Frame = +3

Query: 1  MTEYKLXXXXXXXXXKSALTIQLIQNHFVDE 31
          M EYKL         KSALT+Q +Q  FV++
Sbjct: 48 MREYKLVVLGSGGVGKSALTVQFVQGIFVEK 140
>14456
          Length = 1867

 Score = 82.4 bits (202), Expect = 1e-16,   Method: Compositional matrix adjust.
 Identities = 48/154 (31%), Positives = 83/154 (53%), Gaps = 5/154 (3%)
 Frame = -1

Query: 16   KSALTIQLIQNHFVDEYDPTIEDSY-RKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRT 74
            KS+L  + + N F  +   TI   +  K VV+D ET  + I DTAGQE + ++R  + R 
Sbjct: 1102 KSSLMNRFVSNKFDAQSFHTIGVEFLNKDVVVDDETYTMQIWDTAGQERFKSLRTPFYRG 923

Query: 75   GEGFLCVFAINNTKSFEDIHHYREQI---KSVKDSEDVPMVLVGNKCDLPSRTVDTKQAQ 131
             +  L  F++++ +SF ++  +R++      ++D    P V++GNK D+  R V  ++A+
Sbjct: 922  ADCCLLTFSVDSMQSFRNLSMWRKEFLYYADIQDGVTFPFVVLGNKIDVEGRQVTNEEAR 743

Query: 132  ELARS-YGIPFIETSAKTRQGVDDAFYTLVREIR 164
                +    P+ ETSAK    V+ AF   V+ +R
Sbjct: 742  SWCTANSNAPYFETSAKDATNVEKAFLAAVQRLR 641
>08428
          Length = 1109

 Score = 78.6 bits (192), Expect = 2e-15,   Method: Compositional matrix adjust.
 Identities = 46/150 (30%), Positives = 79/150 (52%), Gaps = 2/150 (1%)
 Frame = -3

Query: 16   KSALTIQLIQNHFVDEYDPTIEDSY-RKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRT 74
            KS++ ++ +   +    + TI  S+  K +V+DG      I DTAGQE++ A+   Y R 
Sbjct: 1032 KSSIVLRFVTGSYRPSQESTIGASFMSKSLVVDGAGYRFQIWDTAGQEKFRALAPMYYRG 853

Query: 75   GEGFLCVFAINNTKSFEDIHHYREQIKSVKDSEDVPMVLVGNKCDLPS-RTVDTKQAQEL 133
                + V+ +   ++F+ +  + ++++S     ++ + + GNKCDL   R V  K AQE 
Sbjct: 852  AAAAVIVYDVTRPRTFKSVKSWIQELRSF-GPPNIVLAIAGNKCDLEELREVVEKDAQEY 676

Query: 134  ARSYGIPFIETSAKTRQGVDDAFYTLVREI 163
            A S    F ETSA T   V++ F  L R++
Sbjct: 675  ASSISAIFGETSAMTAVNVEEMFTELARQL 586
>34468
          Length = 1502

 Score = 78.2 bits (191), Expect = 2e-15,   Method: Compositional matrix adjust.
 Identities = 50/155 (32%), Positives = 81/155 (52%), Gaps = 6/155 (3%)
 Frame = +1

Query: 16  KSALTIQLIQNHFVDEYDPTIEDSYR-KQVVIDGETCLLDILDTAGQEEY-SAMRDQYMR 73
           K+ LT +     F D+ + TI   +R K + +D E   L + DTAGQE +  +M   Y R
Sbjct: 532 KTCLTYRFCLGKFPDKTEATIGVDFREKSIQVDSEHLKLQLWDTAGQERFRKSMVQHYYR 711

Query: 74  TGEGFLCVFAINNTKSFEDIHHYREQIKSVKDSEDVPMVLVGNKCDLPSR-TVDTKQAQE 132
                + V+ +    SFE++  + E+      ++ +P +LVGNKCD+  R  V+T  AQ+
Sbjct: 712 NVHAVVFVYDMTKMSSFENMPAWIEECDRHNLTKYIPRILVGNKCDVVERIAVNTNLAQK 891

Query: 133 LARSYGIPFIETSAK---TRQGVDDAFYTLVREIR 164
            A ++ +P  ETSAK       VD  F T+  +++
Sbjct: 892 FADAHNMPLFETSAKDDEKANHVDAIFMTVAHKLK 996
>33374
          Length = 489

 Score = 66.6 bits (161), Expect = 5e-12,   Method: Compositional matrix adjust.
 Identities = 38/112 (33%), Positives = 62/112 (55%), Gaps = 1/112 (0%)
 Frame = +1

Query: 44  VVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKSV 103
           V +D  T   +I DTAGQE Y ++   Y R  +  + V+ I N  +F     + ++++  
Sbjct: 154 VCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNQDTFGRAKTWVKELQR- 330

Query: 104 KDSEDVPMVLVGNKCDLPS-RTVDTKQAQELARSYGIPFIETSAKTRQGVDD 154
           + S ++ + L GNK DL + R V+ ++AQ  A    + F+ETSAKT   V+D
Sbjct: 331 QASPNIVIALAGNKADLANKRMVEFEEAQAYAEENSLLFMETSAKTAMNVND 486
>07465
          Length = 1103

 Score = 65.1 bits (157), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 42/135 (31%), Positives = 69/135 (51%), Gaps = 2/135 (1%)
 Frame = +3

Query: 28  FVDEYDPTIE-DSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINN 86
           F  +Y  TI  D   +Q+ + GE   L + DTAGQEE+ A+   Y R  +  +  F+  +
Sbjct: 273 FTKDYKKTIGVDFLERQIEVGGEDVRLMLWDTAGQEEFDAITKAYYRGAQACVLAFSTVD 452

Query: 87  TKSFEDIHHYREQIKSVKDSEDVPMVLVGNKCDL-PSRTVDTKQAQELARSYGIPFIETS 145
             SFE +  ++ +++   +  ++ MV+V NK DL     V  ++A+ LA+   + F  TS
Sbjct: 453 RDSFEALETWKRKVED--EVGEIGMVIVQNKIDLIDDAVVRPEEAENLAKKLRLRFYRTS 626

Query: 146 AKTRQGVDDAFYTLV 160
            K    VD+ F  L 
Sbjct: 627 VKENMNVDEVFRYLA 671
>11728
          Length = 635

 Score = 63.9 bits (154), Expect = 4e-11,   Method: Compositional matrix adjust.
 Identities = 35/105 (33%), Positives = 55/105 (52%)
 Frame = -1

Query: 16  KSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTG 75
           K+ L I    N F  EY PT+ D+Y   V++D +   L + DTAGQE+Y  +R       
Sbjct: 452 KTCLLISYTTNAFPGEYIPTVFDNYSANVMVDSKPINLGLWDTAGQEDYDRLRPLSYPQT 273

Query: 76  EGFLCVFAINNTKSFEDIHHYREQIKSVKDSEDVPMVLVGNKCDL 120
           + FL  F++ +  SFE++   +   +      + P++LVG K DL
Sbjct: 272 DVFLICFSLISPASFENVKA-KWYPEVSHHCPNTPIILVGTKLDL 141
>17511
          Length = 483

 Score = 61.6 bits (148), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 33/109 (30%), Positives = 58/109 (53%), Gaps = 4/109 (3%)
 Frame = -3

Query: 16  KSALTIQLIQNHFVDEYDPTI-EDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRT 74
           K++L  Q +   F ++Y  TI  D   K+V++D     + I DTAGQE + ++   + R 
Sbjct: 328 KTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQIWDTAGQERFQSLGVAFYRG 149

Query: 75  GEGFLCVFAINNTKSFEDIHHYREQI---KSVKDSEDVPMVLVGNKCDL 120
            +  + VF +    +F  +  +R++     S +D E+ P V++GNK DL
Sbjct: 148 ADCCVLVFDVTMPNTFRSLDSWRDEFLIQASPRDPENFPFVVIGNKIDL 2
>01972
          Length = 2359

 Score = 61.2 bits (147), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 31/111 (27%), Positives = 61/111 (54%)
 Frame = +3

Query: 53  LDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKSVKDSEDVPMV 112
            ++ DTAGQE++  +RD Y   G+  + +F + +  +++++ ++   +  V+  E++P+V
Sbjct: 453 FNVWDTAGQEKFGGLRDGYYIQGQCAVIMFDVTSRVTYKNVPNWHRDL--VRVCENIPIV 626

Query: 113 LVGNKCDLPSRTVDTKQAQELARSYGIPFIETSAKTRQGVDDAFYTLVREI 163
           L GNK D+  R V  K A    R   + + + SAK+    +  F  L R++
Sbjct: 627 LCGNKVDIKDRKVKAK-AIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKL 776
>13745
          Length = 1045

 Score = 60.8 bits (146), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 34/105 (32%), Positives = 60/105 (57%), Gaps = 4/105 (3%)
 Frame = +2

Query: 61  QEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQI---KSVKDSEDVPMVLVGNK 117
           QE + ++   + R  +  + V+ +    SF+++  +R++     S +D E  P V++GNK
Sbjct: 2   QERFQSLGVAFYRGADCCVLVYDVTAPNSFKNLDSWRDEFLIQASPRDPEHFPFVVLGNK 181

Query: 118 CDLPSRTVDTKQAQELARSYG-IPFIETSAKTRQGVDDAFYTLVR 161
            DL +R V T++AQ+  +S   IP+ ETSAK    V+ AF T+ +
Sbjct: 182 VDLDNRQVSTRRAQQWCQSKNDIPYYETSAKEGINVEMAFQTIAK 316
>19656
          Length = 428

 Score = 60.5 bits (145), Expect = 4e-10,   Method: Compositional matrix adjust.
 Identities = 30/78 (38%), Positives = 43/78 (55%)
 Frame = +3

Query: 16  KSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTG 75
           K+ L I    N F  EY PT+ D+Y   V++DG    L + DTAGQE+Y  +R       
Sbjct: 150 KTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGRPVNLGLWDTAGQEDYDRLRPLSYPQT 329

Query: 76  EGFLCVFAINNTKSFEDI 93
           + FL  F++ +  SFE+I
Sbjct: 330 DVFLLCFSVASPASFENI 383
>12339
          Length = 578

 Score = 58.9 bits (141), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 32/105 (30%), Positives = 56/105 (53%), Gaps = 4/105 (3%)
 Frame = -2

Query: 61  QEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQI---KSVKDSEDVPMVLVGNK 117
           QE + ++   + R  +  + V+ +   K+F+ +  ++ +     S +D E  P V++GNK
Sbjct: 577 QERFQSLGVAFYRGADCCILVYDVTEXKTFDSLDSWQREFLNQASPRDPEHFPFVVIGNK 398

Query: 118 CDLPSRTVDTKQAQELARSYG-IPFIETSAKTRQGVDDAFYTLVR 161
            DL +R V  K+ Q    + G IP+ ETSAK    V+ AF T+ +
Sbjct: 397 IDLDNRVVTAKRGQGWCSTKGGIPYFETSAKEAINVEQAFQTVAK 263
>33380
          Length = 282

 Score = 58.2 bits (139), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 29/73 (39%), Positives = 41/73 (56%)
 Frame = +3

Query: 53  LDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKSVKDSEDVPMV 112
           L I DTAGQE Y  +   Y R   GF+ ++ + N +SF  +  +  QIK+    ++  +V
Sbjct: 66  LQIWDTAGQERYRTITTAYYRGAMGFILMYDVTNEESFNAVQDWCTQIKTYS-WDNAQVV 242

Query: 113 LVGNKCDLPSRTV 125
           LVGNKCDL    V
Sbjct: 243 LVGNKCDLEDERV 281
>19006
          Length = 568

 Score = 56.6 bits (135), Expect = 6e-09,   Method: Compositional matrix adjust.
 Identities = 33/106 (31%), Positives = 58/106 (54%), Gaps = 1/106 (0%)
 Frame = -2

Query: 16  KSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTG 75
           K+ L I   ++ F + Y PT+ ++Y   + +D +   L + DTAGQE+Y  +R       
Sbjct: 399 KTCLLIVFSKDQFPEVYVPTVFENYVADIEVDSKQVELALWDTAGQEDYDRLRPLSYPDT 220

Query: 76  EGFLCVFAINNTKSFEDI-HHYREQIKSVKDSEDVPMVLVGNKCDL 120
           +  L  F+I++  S E+I   +  +++      +VP++LVGNK DL
Sbjct: 219 DVILMCFSIDSPDSLENIPEKWTPEVRHF--CPNVPIILVGNKKDL 88
>34359
          Length = 1042

 Score = 53.1 bits (126), Expect = 6e-08,   Method: Compositional matrix adjust.
 Identities = 26/103 (25%), Positives = 56/103 (54%), Gaps = 5/103 (4%)
 Frame = +3

Query: 53  LDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKSVKDSEDVPMV 112
            ++ DTAGQE++  +RD Y   G   + +F + +  +++++ ++   +  V+  E++P+V
Sbjct: 201 FNVWDTAGQEKFGGLRDGYYIQGTCAIIMFDVTSRVTYKNVPNWHRDL--VRVCENIPIV 374

Query: 113 LVGNKCDLPSRTVDTK-----QAQELARSYGIPFIETSAKTRQ 150
           L GNK D+  R V  K     + +  + +  +P   T+ ++R 
Sbjct: 375 LCGNKVDIKDRKVKAKAIVFHRKRTCSTTTSVPRATTTLRSRS 503
>26083
          Length = 432

 Score = 52.8 bits (125), Expect = 8e-08,   Method: Compositional matrix adjust.
 Identities = 33/118 (27%), Positives = 60/118 (50%), Gaps = 1/118 (0%)
 Frame = +1

Query: 1   MTEYKLXXXXXXXXXKSALTIQLIQNHFVDEYDPTIE-DSYRKQVVIDGETCLLDILDTA 59
           + ++KL         K++L  + + + F + Y  TI  D   K + ++  T  L + DTA
Sbjct: 70  LRKFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTIRLQLWDTA 249

Query: 60  GQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKSVKDSEDVPMVLVGNK 117
           GQE + ++   Y+R     + V+ I N  SF     + + +++ + S DV ++LVGNK
Sbjct: 250 GQERFRSLIPSYIRDSSVAVVVYDITNANSFHQTSKWIDDVRTERGS-DVIIMLVGNK 420
>34597
          Length = 773

 Score = 52.8 bits (125), Expect = 8e-08,   Method: Compositional matrix adjust.
 Identities = 30/85 (35%), Positives = 47/85 (55%), Gaps = 1/85 (1%)
 Frame = -2

Query: 80  CVFAINNTKSFEDIHHYREQIKSVKDSEDVPMVLVGNKCDLP-SRTVDTKQAQELARSYG 138
           C+      KSFE+I  +   I     +EDV  +++GNKCD+   R V  ++ + +AR + 
Sbjct: 736 CLMT*RMKKSFENIVKWLRNIDE-HANEDVEKMILGNKCDMTDKRVVSKERGEAIAREHS 560

Query: 139 IPFIETSAKTRQGVDDAFYTLVREI 163
           I F+ETSAK+   ++ AF  L   I
Sbjct: 559 IRFMETSAKSNINIERAFCELAEAI 485
>32723
          Length = 384

 Score = 48.1 bits (113), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 29/104 (27%), Positives = 53/104 (50%), Gaps = 1/104 (0%)
 Frame = +2

Query: 61  QEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKSVKDSEDVPMVLVGNKCD- 119
           QE + ++   Y R+    + V+ + + +S+E +  +  +I+    ++ V   LVGNK D 
Sbjct: 2   QERFRSITQSYYRSANALILVYDVCSQQSYESLPQWIHEIELYAGTK-VLAFLVGNKIDQ 178

Query: 120 LPSRTVDTKQAQELARSYGIPFIETSAKTRQGVDDAFYTLVREI 163
              R + T   +E A  Y + F+ETSAK    V+  F T+  ++
Sbjct: 179 TDKREIPTHIGKEFAERYEMRFLETSAKEADNVEKLFSTIAYQL 310
>01095
          Length = 1745

 Score = 45.1 bits (105), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 26/85 (30%), Positives = 48/85 (56%), Gaps = 1/85 (1%)
 Frame = -1

Query: 80   CVFAINNTKSFEDIHHYREQIKSVKDSEDVPMVLVGNKCDLPS-RTVDTKQAQELARSYG 138
             V+ I N  +F     + ++++  + S ++ + L GNK DL + R V+ ++AQ  A    
Sbjct: 1745 VVYDITNQDTFGRAKTWVKELQR-QASPNIVIALAGNKADLANKRMVEFEEAQAYAEENS 1569

Query: 139  IPFIETSAKTRQGVDDAFYTLVREI 163
            + F+ETSAKT   V+D F  + +++
Sbjct: 1568 LLFMETSAKTAMNVNDIFLAIAKKL 1494
>31291
          Length = 446

 Score = 44.7 bits (104), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 36/124 (29%), Positives = 60/124 (48%), Gaps = 15/124 (12%)
 Frame = -1

Query: 53  LDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIH-HYREQIKSVKDSEDVPM 111
           L + DTAGQE+Y  +R       + F+  F++ +  S +++   +  +I+       VP+
Sbjct: 446 LQLWDTAGQEDYDRLRPLAYPNTDVFMLXFSLMSEASMKNVKVKWYPEIRH--HDPHVPI 273

Query: 112 VLVGNKCDL-----------PSR--TVDTKQAQELARSYGIP-FIETSAKTRQGVDDAFY 157
           VLVG K DL            SR   V + Q  +LA++     + E S+KT++ +  AF 
Sbjct: 272 VLVGTKLDLRQDKEAVRKLRSSRQDPVSSNQGNDLAKAIKAKRYFECSSKTQENLKTAFE 93

Query: 158 TLVR 161
             VR
Sbjct: 92  ETVR 81
>25655
          Length = 871

 Score = 33.1 bits (74), Expect(2) = 4e-05,   Method: Compositional matrix adjust.
 Identities = 13/21 (61%), Positives = 17/21 (80%)
 Frame = -3

Query: 131 QELARSYGIPFIETSAKTRQG 151
           + +A  Y IP++ETSAKTRQG
Sbjct: 869 KHMAELYHIPYVETSAKTRQG 807

 Score = 30.0 bits (66), Expect(2) = 4e-05,   Method: Compositional matrix adjust.
 Identities = 13/13 (100%), Positives = 13/13 (100%)
 Frame = -2

Query: 152 VDDAFYTLVREIR 164
           VDDAFYTLVREIR
Sbjct: 807 VDDAFYTLVREIR 769
>00552
          Length = 455

 Score = 37.4 bits (85), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 15/46 (32%), Positives = 27/46 (58%)
 Frame = -3

Query: 55  ILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQI 100
           I DTAGQE Y ++R  + R  +  L  F+++N KS + +  + ++ 
Sbjct: 147 IWDTAGQERYKSLRTPFYRGTDCCLLTFSVDNLKSLQSLSDWYDEF 10
>31928
          Length = 429

 Score = 33.9 bits (76), Expect = 0.044,   Method: Compositional matrix adjust.
 Identities = 24/87 (27%), Positives = 41/87 (47%), Gaps = 4/87 (4%)
 Frame = +2

Query: 35  TIEDSYRKQVVID-GETCLLDILDTAGQEEYSAMRD---QYMRTGEGFLCVFAINNTKSF 90
           TIED Y   +  D G    + I DT      +   D    Y+   +GF+ V+   + +SF
Sbjct: 53  TIEDIYTAVIETDRGVKEKVRIFDTGAAALETTEGDLPKHYLNFPDGFVLVYDTTSWESF 232

Query: 91  EDIHHYREQIKSVKDSEDVPMVLVGNK 117
             +   ++ I   +D  +V M+++GNK
Sbjct: 233 RRLDKLKKDIDKHRDKREVHMIVIGNK 313
>21396
          Length = 647

 Score = 32.0 bits (71), Expect = 0.17,   Method: Compositional matrix adjust.
 Identities = 15/42 (35%), Positives = 21/42 (50%)
 Frame = -2

Query: 28  FVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRD 69
           F +E  PT       Q +  G  CLL +L T+  E +S +RD
Sbjct: 388 FFEELRPTTSHHDHTQSLFHGRLCLLFLLCTSALEIHSFLRD 263
>09700
          Length = 1855

 Score = 30.8 bits (68), Expect = 0.32,   Method: Compositional matrix adjust.
 Identities = 19/69 (27%), Positives = 32/69 (46%), Gaps = 13/69 (18%)
 Frame = -1

Query: 101  KSVKDSEDVPMVLVGNKCDLPS-------------RTVDTKQAQELARSYGIPFIETSAK 147
            +S  +S   P+VLVG + DL +             + V    A +LA   G  ++E SA 
Sbjct: 1840 RSANNSPRTPLVLVGTQSDLRNDVKVLIELAKYKEKPVSEDDASKLAHQLGASYVECSAL 1661

Query: 148  TRQGVDDAF 156
            T++ + + F
Sbjct: 1660 TQKNLKEMF 1634
>10708
          Length = 2775

 Score = 30.4 bits (67), Expect = 0.42,   Method: Compositional matrix adjust.
 Identities = 15/41 (36%), Positives = 23/41 (56%)
 Frame = -2

Query: 53   LDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDI 93
            L + DTAGQE+Y  +R       +  L  F+I++  S E+I
Sbjct: 2717 LALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENI 2595
>35581
          Length = 364

 Score = 30.0 bits (66), Expect = 0.62,   Method: Compositional matrix adjust.
 Identities = 13/35 (37%), Positives = 19/35 (54%)
 Frame = +2

Query: 48  GETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVF 82
           G    +D+ DTAGQE Y ++   Y R  +  L V+
Sbjct: 185 GVMASVDLWDTAGQERYRSLTSSYYRDTKAVLIVY 289
>27191
          Length = 443

 Score = 26.6 bits (57), Expect = 7.0,   Method: Compositional matrix adjust.
 Identities = 11/22 (50%), Positives = 16/22 (72%)
 Frame = +2

Query: 141 FIETSAKTRQGVDDAFYTLVRE 162
           + ETSA T +GVDD F  +++E
Sbjct: 377 YYETSAATGEGVDDMFQQMLQE 442
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|33468987|ref|NP_080512.1| WD repeat domain 48 [Mus
musculus]
         (676 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

19140                                                                 256   2e-68
30256                                                                  79   6e-15
00561                                                                  70   2e-12
17598                                                                  69   5e-12
13335                                                                  62   6e-10
12574                                                                  59   7e-09
02147                                                                  59   9e-09
19949                                                                  54   3e-07
01327                                                                  52   9e-07
03156                                                                  52   1e-06
13278                                                                  51   1e-06
27465                                                                  50   2e-06
15780                                                                  50   3e-06
18981                                                                  49   7e-06
17266                                                                  48   1e-05
12960                                                                  48   1e-05
02090                                                                  47   2e-05
26939                                                                  47   3e-05
17602                                                                  47   3e-05
21105                                                                  47   3e-05
19498                                                                  46   6e-05
01462                                                                  45   7e-05
12806                                                                  45   7e-05
10162                                                                  44   2e-04
37180                                                                  44   3e-04
31864                                                                  44   3e-04
21921                                                                  44   3e-04
03395                                                                  43   3e-04
31474                                                                  42   7e-04
19863                                                                  42   9e-04
11493                                                                  40   0.003
01598                                                                  37   0.022
25880                                                                  37   0.028
01249                                                                  36   0.048
31384                                                                  36   0.057
15337                                                                  36   0.058
11915                                                                  35   0.075
12140                                                                  35   0.076
14500                                                                  35   0.081
16105                                                                  35   0.084
14555                                                                  35   0.088
17298                                                                  35   0.090
26107                                                                  35   0.10 
20662                                                                  34   0.25 
34005                                                                  33   0.27 
00825                                                                  32   0.61 
30297                                                                  32   0.63 
04358                                                                  32   0.67 
04524                                                                  32   0.93 
30295                                                                  32   0.99 
06898                                                                  32   1.0  
15118                                                                  32   1.2  
13890                                                                  32   1.2  
02960                                                                  31   1.3  
04088                                                                  31   1.7  
25930                                                                  31   1.7  
27681                                                                  31   2.0  
07151                                                                  30   2.2  
33180                                                                  30   4.0  
38039                                                                  30   4.5  
07665                                                                  29   4.8  
16199                                                                  29   5.7  
03734                                                                  28   8.2  
>19140
          Length = 573

 Score =  256 bits (654), Expect(3) = 2e-68,   Method: Compositional matrix adjust.
 Identities = 126/181 (69%), Positives = 150/181 (82%)
 Frame = -3

Query: 197 PRTCAKLMKLKGHTDNVKALLLHRDGTQCLSGSSDGTIRLWSLGQQRCIATYRVHDEGVW 256
           PRTC KLMKLKGHTDNVKAL+L+RDGTQCLSGSSDGTIRLWSLGQQRC+AT+RVHDEGVW
Sbjct: 526 PRTCHKLMKLKGHTDNVKALVLNRDGTQCLSGSSDGTIRLWSLGQQRCVATFRVHDEGVW 347

Query: 257 ALQVNDAFTHVYSGGRDRKIYCTDLRNPDIRVLICEEKAPVLKMELDRSADPPPAIWVAT 316
           ALQ N++FT +YSGGRD +++ TD++NPD R LICEEKAPVLK+EL  +   PP++WVAT
Sbjct: 346 ALQANESFTTLYSGGRDHQVWATDIKNPDNRELICEEKAPVLKLEL--TPTDPPSLWVAT 173

Query: 317 TKSTVNKWTLKGIHNFRASGDYDNDCTNPITPLCTQPDQVIKGGASIIQCHILNDKRHIL 376
           T S +  W ++ + N RASG+YDND    I P  TQPD VIKGG SI Q ++LND+RHIL
Sbjct: 172 TDSCIKNWPVR-LPNPRASGEYDND---RIHPTATQPDFVIKGGPSIRQYNVLNDRRHIL 5

Query: 377 T 377
           T
Sbjct: 4   T 2

 Score = 21.9 bits (45), Expect(3) = 2e-68,   Method: Composition-based stats.
 Identities = 9/10 (90%), Positives = 10/10 (100%)
 Frame = -2

Query: 181 TIIVSGSTEK 190
           T+IVSGSTEK
Sbjct: 572 TVIVSGSTEK 543

 Score = 21.6 bits (44), Expect(3) = 2e-68,   Method: Compositional matrix adjust.
 Identities = 8/8 (100%), Positives = 8/8 (100%)
 Frame = -1

Query: 190 KVLRVWDP 197
           KVLRVWDP
Sbjct: 546 KVLRVWDP 523

 Score = 47.4 bits (111), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 25/78 (32%), Positives = 43/78 (55%)
 Frame = -3

Query: 68  IASMEHHTDWVNDVVLCCNGKTLISASSDTTVKVWNAHKGFCMSTLRTHKDYVKALAYAK 127
           +  ++ HTD V  +VL  +G   +S SSD T+++W+  +  C++T R H + V AL   +
Sbjct: 508 LMKLKGHTDNVKALVLNRDGTQCLSGSSDGTIRLWSLGQQRCVATFRVHDEGVWALQANE 329

Query: 128 DKELVASAGLDRQIFLWD 145
               + S G D Q++  D
Sbjct: 328 SFTTLYSGGRDHQVWATD 275
>30256
          Length = 961

 Score = 79.0 bits (193), Expect = 6e-15,   Method: Compositional matrix adjust.
 Identities = 58/190 (30%), Positives = 90/190 (47%)
 Frame = +3

Query: 87  GKTLISASSDTTVKVWNAHKGFCMSTLRTHKDYVKALAYAKDKELVASAGLDRQIFLWDX 146
           G T+IS S+D ++KVWNA  G C  TL  H   V+ L+ +  K  V S   D  + +WD 
Sbjct: 72  GNTVISGSTDRSLKVWNADTGVCTHTLYGHSSTVRCLSLSGKK--VVSGSRDATLRVWD- 242

Query: 147 XXXXXXXXXXXXXXXXXXXGNKDSIYSLAMNQLGTIIVSGSTEKVLRVWDPRTCAKLMKL 206
                              G+  ++  +  +  G  +VSG+ +  +RVWDP T + L  L
Sbjct: 243 --------IESGHCLNVLLGHMAAVRCVQYD--GKRVVSGAXDYTVRVWDPDTASCLHTL 392

Query: 207 KGHTDNVKALLLHRDGTQCLSGSSDGTIRLWSLGQQRCIATYRVHDEGVWALQVNDAFTH 266
           +GHT+ V +L    DG   +SGS D +IR+W +   + + T   H      L++ D    
Sbjct: 393 QGHTNRVYSLQF--DGVYVVSGSLDTSIRVWDVRCGKLVHTLMGHQSLTSGLELKDNL-- 560

Query: 267 VYSGGRDRKI 276
           + SG  D  +
Sbjct: 561 LVSGNADSTV 590

 Score = 76.6 bits (187), Expect = 3e-14,   Method: Compositional matrix adjust.
 Identities = 70/253 (27%), Positives = 114/253 (45%), Gaps = 5/253 (1%)
 Frame = +3

Query: 43  NRLFTAGRDSIIRIWSVNQHKQDPYIASMEHHTDWVNDVVLCCNGKTLISASSDTTVKVW 102
           N + +   D  +++W+ +         ++  H+  V  + L  +GK ++S S D T++VW
Sbjct: 75  NTVISGSTDRSLKVWNADT---GVCTHTLYGHSSTVRCLSL--SGKKVVSGSRDATLRVW 239

Query: 103 NAHKGFCMSTLRTHKDYVKALAYAKDKELVASAGLDRQIFLWDXXXXXXXXXXXXXXXXX 162
           +   G C++ L  H   V+ + Y  D + V S   D  + +WD                 
Sbjct: 240 DIESGHCLNVLLGHMAAVRCVQY--DGKRVVSGAXDYTVRVWD---------PDTASCLH 386

Query: 163 XXXGNKDSIYSLAMNQLGTIIVSGSTEKVLRVWDPRTCAKLM-KLKGHTDNVKALLLHRD 221
              G+ + +YSL  +  G  +VSGS +  +RVWD R C KL+  L GH      L L  +
Sbjct: 387 TLQGHTNRVYSLQFD--GVYVVSGSLDTSIRVWDVR-CGKLVHTLMGHQSLTSGLELKDN 557

Query: 222 GTQCLSGSSDGTIRLWSLGQQRCIATY---RVHDEGVWALQVNDAFTHVYSGGRDRKIYC 278
               +SG++D T+++W +   +C+ T      H   V  LQ N  F  V +   D  +  
Sbjct: 558 --LLVSGNADSTVKVWDVHTGKCLQTLLGPNKHRSAVTCLQFNKKF--VVTCSDDGTVKL 725

Query: 279 TDLRNPD-IRVLI 290
            DL   D IR LI
Sbjct: 726 WDLNTGDFIRNLI 764

 Score = 51.6 bits (122), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 37/120 (30%), Positives = 58/120 (48%)
 Frame = +3

Query: 166 GNKDSIYSLAMNQLGTIIVSGSTEKVLRVWDPRTCAKLMKLKGHTDNVKALLLHRDGTQC 225
           G+   ++S  M   G  ++SGST++ L+VW+  T      L GH+  V+ L L   G + 
Sbjct: 36  GHTGGVWSSQMT--GNTVISGSTDRSLKVWNADTGVCTHTLYGHSSTVRCLSL--SGKKV 203

Query: 226 LSGSSDGTIRLWSLGQQRCIATYRVHDEGVWALQVNDAFTHVYSGGRDRKIYCTDLRNPD 285
           +SGS D T+R+W +    C+     H   V  +Q +     V SG  D   Y   + +PD
Sbjct: 204 VSGSRDATLRVWDIESGHCLNVLLGHMAAVRCVQYDGK--RVVSGAXD---YTVRVWDPD 368
>00561
          Length = 1003

 Score = 70.5 bits (171), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 50/213 (23%), Positives = 89/213 (41%), Gaps = 5/213 (2%)
 Frame = -3

Query: 45  LFTAGRDSIIRIWSVNQHKQDPYIASMEH---HTDWVNDVVLCCNGKTLISASSDTTVKV 101
           + +A RD  + +W + + +   Y    +    H+ +++DVVL  +G   +S S D T+++
Sbjct: 965 IISASRDKTLIVWKLTRDEDTNYGYPQKRLYGHSHFISDVVLSSDGNYALSGSWDQTLRL 786

Query: 102 WNAHKGFCMSTLRTHKDYVKALAYAKDKELVASAGLDRQIFLWDXXXXXXXXXXXXXXXX 161
           W+   G        H   V ++A++ D   + S   D+ I LW+                
Sbjct: 785 WDLAAGKTTRRFEGHTKDVLSVAFSADNRQIVSGSRDKTIKLWN--------TLAECKFT 630

Query: 162 XXXXGNKD--SIYSLAMNQLGTIIVSGSTEKVLRVWDPRTCAKLMKLKGHTDNVKALLLH 219
               G+ D  S    + N    IIVS   ++ ++VW+   C       GH   +  + + 
Sbjct: 629 IQEDGHTDWVSCVRFSPNHSNPIIVSCGWDRTVKVWNLANCKLKNNHHGHNGYLNTVTVS 450

Query: 220 RDGTQCLSGSSDGTIRLWSLGQQRCIATYRVHD 252
            DG+ C SG  D    LW L   + + T   +D
Sbjct: 449 PDGSLCTSGGKDSKALLWDLNDGKNLYTLEHND 351

 Score = 56.6 bits (135), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 48/204 (23%), Positives = 87/204 (42%), Gaps = 9/204 (4%)
 Frame = -3

Query: 89  TLISASSDTTVKVW------NAHKGFCMSTLRTHKDYVKALAYAKDKELVASAGLDRQIF 142
           T+ISAS D T+ VW      + + G+    L  H  ++  +  + D     S   D+ + 
Sbjct: 968 TIISASRDKTLIVWKLTRDEDTNYGYPQKRLYGHSHFISDVVLSSDGNYALSGSWDQTLR 789

Query: 143 LWDXXXXXXXXXXXXXXXXXXXXGNKDSIYSLAMNQLGTIIVSGSTEKVLRVWDPRT-CA 201
           LWD                    G+   + S+A +     IVSGS +K +++W+    C 
Sbjct: 788 LWDLAAGKTTRRFE---------GHTKDVLSVAFSADNRQIVSGSRDKTIKLWNTLAECK 636

Query: 202 KLMKLKGHTDNVKALLLHRDGTQ--CLSGSSDGTIRLWSLGQQRCIATYRVHDEGVWALQ 259
             ++  GHTD V  +    + +    +S   D T+++W+L   +    +  H+  +  + 
Sbjct: 635 FTIQEDGHTDWVSCVRFSPNHSNPIIVSCGWDRTVKVWNLANCKLKNNHHGHNGYLNTVT 456

Query: 260 VNDAFTHVYSGGRDRKIYCTDLRN 283
           V+   +   SGG+D K    DL +
Sbjct: 455 VSPDGSLCTSGGKDSKALLWDLND 384

 Score = 51.2 bits (121), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 41/161 (25%), Positives = 68/161 (42%), Gaps = 4/161 (2%)
 Frame = -3

Query: 127 KDKELVASAGLDRQIFLWDXXXXXXXXXXXXXXXXXXXXGNKDSIYSLAMNQLGTIIVSG 186
           KD + + SA  D+ + +W                     G+   I  + ++  G   +SG
Sbjct: 980 KDPDTIISASRDKTLIVW---KLTRDEDTNYGYPQKRLYGHSHFISDVVLSSDGNYALSG 810

Query: 187 STEKVLRVWDPRTCAKLMKLKGHTDNVKALLLHRDGTQCLSGSSDGTIRLWSLGQQRCIA 246
           S ++ LR+WD        + +GHT +V ++    D  Q +SGS D TI+LW+   + C  
Sbjct: 809 SWDQTLRLWDLAAGKTTRRFEGHTKDVLSVAFSADNRQIVSGSRDKTIKLWNTLAE-CKF 633

Query: 247 TYRVHDEGVWALQVNDAFTH----VYSGGRDRKIYCTDLRN 283
           T +      W   V  +  H    + S G DR +   +L N
Sbjct: 632 TIQEDGHTDWVSCVRFSPNHSNPIIVSCGWDRTVKVWNLAN 510
>17598
          Length = 875

 Score = 69.3 bits (168), Expect = 5e-12,   Method: Compositional matrix adjust.
 Identities = 48/204 (23%), Positives = 93/204 (45%), Gaps = 9/204 (4%)
 Frame = +1

Query: 45  LFTAGRDSIIRIWSVNQHK---QDPYIA----SMEHHTDWVNDVVLCCNGKTLISASSDT 97
           L   GRD ++ +W +   K   +D        +++ H+ +V+DV L  + + ++S+S D 
Sbjct: 10  LIXGGRDKLLIVWDLVPRKDGDEDETWGGPRRTLQGHSHFVSDVSLSADSRYVLSSSWDA 189

Query: 98  TVKVWNAHKGFCMSTLRTHKDYVKALAYAKDKELVASAGLDRQIFLWDXXXXXXXXXXXX 157
           T+++W+  KG       +H     A+A++ D   +AS G D+ + +W+            
Sbjct: 190 TLRLWDIKKGNTTRRFISHTRDALAVAFSPDNRQIASGGRDKALKIWNTVGECKFTVDAN 369

Query: 158 XXXXXXXXGNKDSIYSLAMNQ--LGTIIVSGSTEKVLRVWDPRTCAKLMKLKGHTDNVKA 215
                    ++D +  +  +Q     ++VS S +K ++VWD +T        GH   + A
Sbjct: 370 --------SHQDWVTCVKFHQDAKSPLVVSASMDKTIKVWDNQTMTLKHTFVGHKTQINA 525

Query: 216 LLLHRDGTQCLSGSSDGTIRLWSL 239
           + L        SGS DG +  W++
Sbjct: 526 IDLALKTYYLASGSKDGIVMTWNI 597

 Score = 47.4 bits (111), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 31/113 (27%), Positives = 50/113 (44%), Gaps = 2/113 (1%)
 Frame = +1

Query: 35  ALQLDPALNRLFTAGRDSIIRIWSVNQHKQDPYIASMEHHTDWVNDVVLCCNGKT--LIS 92
           A+   P   ++ + GRD  ++IW  N   +  +      H DWV  V    + K+  ++S
Sbjct: 262 AVAFSPDNRQIASGGRDKALKIW--NTVGECKFTVDANSHQDWVTCVKFHQDAKSPLVVS 435

Query: 93  ASSDTTVKVWNAHKGFCMSTLRTHKDYVKALAYAKDKELVASAGLDRQIFLWD 145
           AS D T+KVW+        T   HK  + A+  A     +AS   D  +  W+
Sbjct: 436 ASMDKTIKVWDNQTMTLKHTFVGHKTQINAIDLALKTYYLASGSKDGIVMTWN 594

 Score = 42.0 bits (97), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 29/105 (27%), Positives = 45/105 (42%), Gaps = 10/105 (9%)
 Frame = +1

Query: 182 IIVSGSTEKVLRVWD--PRT--------CAKLMKLKGHTDNVKALLLHRDGTQCLSGSSD 231
            ++ G  +K+L VWD  PR               L+GH+  V  + L  D    LS S D
Sbjct: 7   FLIXGGRDKLLIVWDLVPRKDGDEDETWGGPRRTLQGHSHFVSDVSLSADSRYVLSSSWD 186

Query: 232 GTIRLWSLGQQRCIATYRVHDEGVWALQVNDAFTHVYSGGRDRKI 276
            T+RLW + +      +  H     A+  +     + SGGRD+ +
Sbjct: 187 ATLRLWDIKKGNTTRRFISHTRDALAVAFSPDNRQIASGGRDKAL 321
>13335
          Length = 863

 Score = 62.4 bits (150), Expect = 6e-10,   Method: Compositional matrix adjust.
 Identities = 58/235 (24%), Positives = 94/235 (40%), Gaps = 16/235 (6%)
 Frame = +1

Query: 21  IRDEVEKYNRNGVNALQLDPALNRLFTAGRDSIIRIWSVNQHKQDPYIASMEHHTDWVND 80
           I+ E +  +++ +   +  P+ + L +   D  I +W V   K    + S   H D V  
Sbjct: 34  IKGEYQHASKSSIRVCKFSPSSSHLVSGSDDDTICMWEVATQK---LVRSYVGHEDSVMA 204

Query: 81  VVLCCNGKTLISASSDTTVKVWNAHKGFCMS-TLR--------THKDYVKALAYAKDKE- 130
           +    NG  L+S S +  + VW+A  G C   TLR        T  ++      A  +  
Sbjct: 205 LAYSPNGHYLVSGSPNGDLYVWDASFGHCRHLTLRVDAHDLGVTCCEFSPTFGTACAENS 384

Query: 131 -----LVASAGLDRQIFLWDXXXXXXXXXXXXXXXXXXXXGNKDSIYSLAMNQLGTIIVS 185
                L+A+ G D  I LW                     G+ D + + A +    ++ S
Sbjct: 385 STCNLLLATGGKDNLIKLW-TFSAQVGSPEVTLQCRDILSGHSDLVMACAFSPSSALLAS 561

Query: 186 GSTEKVLRVWDPRTCAKLMKLKG-HTDNVKALLLHRDGTQCLSGSSDGTIRLWSL 239
           GS +K +R+WD      L  ++  H+  V       DGT   SGS D  I++W L
Sbjct: 562 GSFDKSVRLWDSVKGVALFSIEACHSRFVTCCAFSIDGTLLASGSMDRIIKIWKL 726

 Score = 40.8 bits (94), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 28/123 (22%), Positives = 50/123 (40%), Gaps = 8/123 (6%)
 Frame = +1

Query: 90  LISASSDTTVKVW--NAHKGF------CMSTLRTHKDYVKALAYAKDKELVASAGLDRQI 141
           L +   D  +K+W  +A  G       C   L  H D V A A++    L+AS   D+ +
Sbjct: 403 LATGGKDNLIKLWTFSAQVGSPEVTLQCRDILSGHSDLVMACAFSPSSALLASGSFDKSV 582

Query: 142 FLWDXXXXXXXXXXXXXXXXXXXXGNKDSIYSLAMNQLGTIIVSGSTEKVLRVWDPRTCA 201
            LWD                     +   +   A +  GT++ SGS ++++++W     +
Sbjct: 583 RLWDSVKGVALFSIEAC--------HSRFVTCCAFSIDGTLLASGSMDRIIKIWKLTDTS 738

Query: 202 KLM 204
            +M
Sbjct: 739 SIM 747

 Score = 40.4 bits (93), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 32/103 (31%), Positives = 50/103 (48%), Gaps = 4/103 (3%)
 Frame = +1

Query: 166 GNKDSIYSLAMNQLGTIIVSGSTEKVLRVWDPRTCAKLMKLKGHTDNVKALLLHRDGTQC 225
            +K SI     +   + +VSGS +  + +W+  T   +    GH D+V AL    +G   
Sbjct: 55  ASKSSIRVCKFSPSSSHLVSGSDDDTICMWEVATQKLVRSYVGHEDSVMALAYSPNGHYL 234

Query: 226 LSGSSDGTIRLW--SLGQQRCIATYRV--HDEGVWALQVNDAF 264
           +SGS +G + +W  S G  R + T RV  HD GV   + +  F
Sbjct: 235 VSGSPNGDLYVWDASFGHCRHL-TLRVDAHDLGVTCCEFSPTF 360

 Score = 33.9 bits (76), Expect = 0.24,   Method: Compositional matrix adjust.
 Identities = 29/121 (23%), Positives = 52/121 (42%), Gaps = 16/121 (13%)
 Frame = +1

Query: 194 VWDPRTCAKLMKLKGH-----TDNVKALLLHRDGTQCLSGSSDGTIRLWSLGQQRCIATY 248
           VWD +T      +KG        +++        +  +SGS D TI +W +  Q+ + +Y
Sbjct: 10  VWDVKT----GSIKGEYQHASKSSIRVCKFSPSSSHLVSGSDDDTICMWEVATQKLVRSY 177

Query: 249 RVHDEGVWALQVNDAFTHVYSGGRDRKIYCTD-----LRNPDIRV------LICEEKAPV 297
             H++ V AL  +    ++ SG  +  +Y  D      R+  +RV      + C E +P 
Sbjct: 178 VGHEDSVMALAYSPNGHYLVSGSPNGDLYVWDASFGHCRHLTLRVDAHDLGVTCCEFSPT 357

Query: 298 L 298
            
Sbjct: 358 F 360

 Score = 32.3 bits (72), Expect = 0.72,   Method: Compositional matrix adjust.
 Identities = 35/134 (26%), Positives = 53/134 (39%), Gaps = 23/134 (17%)
 Frame = +1

Query: 166 GNKDSIYSLAMNQLGTIIVSGSTEKVLRVWDPRT--CAKL-MKLKGHTDNVKALLLHRD- 221
           G++DS+ +LA +  G  +VSGS    L VWD     C  L +++  H   V         
Sbjct: 181 GHEDSVMALAYSPNGHYLVSGSPNGDLYVWDASFGHCRHLTLRVDAHDLGVTCCEFSPTF 360

Query: 222 GTQCLSGSS-----------DGTIRLWSLGQQ--------RCIATYRVHDEGVWALQVND 262
           GT C   SS           D  I+LW+   Q        +C      H + V A   + 
Sbjct: 361 GTACAENSSTCNLLLATGGKDNLIKLWTFSAQVGSPEVTLQCRDILSGHSDLVMACAFSP 540

Query: 263 AFTHVYSGGRDRKI 276
           +   + SG  D+ +
Sbjct: 541 SSALLASGSFDKSV 582
>12574
          Length = 521

 Score = 58.9 bits (141), Expect = 7e-09,   Method: Composition-based stats.
 Identities = 34/108 (31%), Positives = 53/108 (49%)
 Frame = +3

Query: 32  GVNALQLDPALNRLFTAGRDSIIRIWSVNQHKQDPYIASMEHHTDWVNDVVLCCNGKTLI 91
            ++A++  P  + L ++  D +I+IW     K +  IA    H   ++DV    + K L 
Sbjct: 192 ALSAVKFSPNGDWLASSSADKLIKIWGAYDGKFEKTIAG---HKLGLSDVAWSSDSKLLC 362

Query: 92  SASSDTTVKVWNAHKGFCMSTLRTHKDYVKALAYAKDKELVASAGLDR 139
           SAS D T+K+W    G CM TL+ H +YV    +     L+ S  L R
Sbjct: 363 SASDDKTLKIWEFSTGKCMKTLKGHSNYVFCCNFNPQSNLIVSGSLMR 506

 Score = 38.5 bits (88), Expect = 0.008,   Method: Composition-based stats.
 Identities = 21/105 (20%), Positives = 44/105 (41%)
 Frame = +3

Query: 166 GNKDSIYSLAMNQLGTIIVSGSTEKVLRVWDPRTCAKLMKLKGHTDNVKALLLHRDGTQC 225
           G+  ++ ++  +  G  + S S +K++++W          + GH   +  +    D    
Sbjct: 180 GHTKALSAVKFSPNGDWLASSSADKLIKIWGAYDGKFEKTIAGHKLGLSDVAWSSDSKLL 359

Query: 226 LSGSSDGTIRLWSLGQQRCIATYRVHDEGVWALQVNDAFTHVYSG 270
            S S D T+++W     +C+ T + H   V+    N     + SG
Sbjct: 360 CSASDDKTLKIWEFSTGKCMKTLKGHSNYVFCCNFNPQSNLIVSG 494

 Score = 35.0 bits (79), Expect = 0.089,   Method: Composition-based stats.
 Identities = 26/118 (22%), Positives = 51/118 (43%)
 Frame = +3

Query: 112 TLRTHKDYVKALAYAKDKELVASAGLDRQIFLWDXXXXXXXXXXXXXXXXXXXXGNKDSI 171
           TL  H   + A+ ++ + + +AS+  D+ I +W                     G+K  +
Sbjct: 171 TLAGHTKALSAVKFSPNGDWLASSSADKLIKIWGAYDGKFEKTIA---------GHKLGL 323

Query: 172 YSLAMNQLGTIIVSGSTEKVLRVWDPRTCAKLMKLKGHTDNVKALLLHRDGTQCLSGS 229
             +A +    ++ S S +K L++W+  T   +  LKGH++ V     +      +SGS
Sbjct: 324 SDVAWSSDSKLLCSASDDKTLKIWEFSTGKCMKTLKGHSNYVFCCNFNPQSNLIVSGS 497
>02147
          Length = 1547

 Score = 58.5 bits (140), Expect = 9e-09,   Method: Compositional matrix adjust.
 Identities = 45/174 (25%), Positives = 70/174 (40%), Gaps = 1/174 (0%)
 Frame = +2

Query: 67  YIASMEHHTDWVNDVVLCCNGKTLISASSDTTVKVWNAHKGFCMSTLRTHKDYVKALAYA 126
           +I + E H   V    L        + ++D + K+W+A KG  + T  +HK  VK++ ++
Sbjct: 149 WIGTFEGHKGAVWGATLNREATRAATGAADFSAKIWDAEKGEELQTF-SHKHIVKSVDFS 325

Query: 127 KDKELVASAGLDRQIFLWDXXXXXXXXXXXXXXXXXXXXGNKDSIYSLAMNQLGTIIVSG 186
            D                                                   GT +++G
Sbjct: 326 HD---------------------------------------------------GTALLTG 352

Query: 187 STEKVLRVWD-PRTCAKLMKLKGHTDNVKALLLHRDGTQCLSGSSDGTIRLWSL 239
           S EK+L+V+D   T A+     GHT N+K  L   DG + +S S D T+RLWSL
Sbjct: 353 SNEKLLKVFDLVNTDAEPKSFAGHTSNIKGALFLSDGKRIISASDDKTVRLWSL 514

 Score = 49.3 bits (116), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 44/195 (22%), Positives = 78/195 (40%), Gaps = 2/195 (1%)
 Frame = +2

Query: 45  LFTAGRDSIIRIWSVNQHKQDPYIASMEHHTDWVNDVVLCCNGKTLISASSDTTVKVWNA 104
           L T   + +++++ +     +P   S   HT  +   +   +GK +ISAS D TV++W+ 
Sbjct: 341 LLTGSNEKLLKVFDLVNTDAEP--KSFAGHTSNIKGALFLSDGKRIISASDDKTVRLWSL 514

Query: 105 HKGFCMSTLR-THKDYVKALAYAKDKE-LVASAGLDRQIFLWDXXXXXXXXXXXXXXXXX 162
               C    + T      +L  + DK  ++ +   +   +  D                 
Sbjct: 515 ET--CQEVQQLTFDTPPTSLTLSPDKNTIIVTHSQNIAFYQADTLREMKKFEAEA----- 673

Query: 163 XXXGNKDSIYSLAMNQLGTIIVSGSTEKVLRVWDPRTCAKLMKLKGHTDNVKALLLHRDG 222
                   I S +++Q     V+G  +  +  +D  T  ++   KGH   V  +    DG
Sbjct: 674 -------PISSASLHQSERFFVAGGEDFKMYKFDYETGKEIESFKGHFGPVHCVRFSPDG 832

Query: 223 TQCLSGSSDGTIRLW 237
               SGS DGT+RLW
Sbjct: 833 ELYASGSEDGTLRLW 877
>19949
          Length = 903

 Score = 53.5 bits (127), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 32/111 (28%), Positives = 51/111 (45%)
 Frame = +2

Query: 171 IYSLAMNQLGTIIVSGSTEKVLRVWDPRTCAKLMKLKGHTDNVKALLLHRDGTQCLSGSS 230
           + SL  +  G    SGS +  +++WD R    +   KGHT  V  L    DG    S S 
Sbjct: 2   VKSLDFHPYGAYTASGSMDCNVKLWDIRRKGCIYTYKGHTGCVCCLRFSPDGRWIASASE 181

Query: 231 DGTIRLWSLGQQRCIATYRVHDEGVWALQVNDAFTHVYSGGRDRKIYCTDL 281
           DG ++LW L   + +   ++H + V  ++ +     + SG  DR +   DL
Sbjct: 182 DGLVKLWDLTAGKLLTDLKLHRDAVNTIEFHPHEFLLASGSADRTVKFWDL 334

 Score = 50.8 bits (120), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 40/167 (23%), Positives = 72/167 (43%), Gaps = 2/167 (1%)
 Frame = +2

Query: 33  VNALQLDPALNRLFTAGRDSIIRIWSVNQHKQDPYIASMEHHTDWVNDVVLCCNGKTLIS 92
           V +L   P      +   D  +++W +   ++   I + + HT  V  +    +G+ + S
Sbjct: 2   VKSLDFHPYGAYTASGSMDCNVKLWDI---RRKGCIYTYKGHTGCVCCLRFSPDGRWIAS 172

Query: 93  ASSDTTVKVWNAHKGFCMSTLRTHKDYVKALAYAKDKELVASAGLDRQIFLWDXXXXXXX 152
           AS D  VK+W+   G  ++ L+ H+D V  + +   + L+AS   DR +  WD       
Sbjct: 173 ASEDGLVKLWDLTAGKLLTDLKLHRDAVNTIEFHPHEFLLASGSADRTVKFWDLETFQLI 352

Query: 153 XXXXXXXXXXXXXGNKDSIYSLAMNQLGTIIVSGSTEKVLRV--WDP 197
                           +SI S+  +  G  + SGS +  L+V  W+P
Sbjct: 353 STTEP---------EANSIRSILFHPDGVCLYSGSKD-TLKVYHWEP 463

 Score = 48.5 bits (114), Expect = 9e-06,   Method: Compositional matrix adjust.
 Identities = 39/159 (24%), Positives = 64/159 (40%), Gaps = 1/159 (0%)
 Frame = +2

Query: 120 VKALAYAKDKELVASAGLDRQIFLWDXXXXXXXXXXXXXXXXXXXXGNKDSIYSLAMNQL 179
           VK+L +       AS  +D  + LWD                    G+   +  L  +  
Sbjct: 2   VKSLDFHPYGAYTASGSMDCNVKLWDIRRKGCIYTYK---------GHTGCVCCLRFSPD 154

Query: 180 GTIIVSGSTEKVLRVWDPRTCAKLMKLKGHTDNVKALLLHRDGTQCLSGSSDGTIRLWSL 239
           G  I S S + ++++WD      L  LK H D V  +  H       SGS+D T++ W L
Sbjct: 155 GRWIASASEDGLVKLWDLTAGKLLTDLKLHRDAVNTIEFHPHEFLLASGSADRTVKFWDL 334

Query: 240 GQQRCIATYRVHDEGVWALQVNDAFTHVYSGGRDR-KIY 277
              + I+T       + ++  +     +YSG +D  K+Y
Sbjct: 335 ETFQLISTTEPEANSIRSILFHPDGVCLYSGSKDTLKVY 451
>01327
          Length = 2215

 Score = 52.0 bits (123), Expect = 9e-07,   Method: Compositional matrix adjust.
 Identities = 48/221 (21%), Positives = 86/221 (38%), Gaps = 6/221 (2%)
 Frame = +3

Query: 40  PALNRLFTAGRDSIIRIWSV-NQHKQDPYIASMEHHTDWVNDVVLCCNGKTLISASSDTT 98
            + N +F+A RD  I++W   N H    +I     H   V  + L  +   L S S D T
Sbjct: 195 ASCNGMFSASRDKTIKMWQRGNSHSIRDFIG----HDMVVTAIHLNTDNTLLCSGSRDNT 362

Query: 99  VKVWNAHKGFCMSTLRTHKDYVKALAYAKDKELVASAGLDRQIFLWDXXXXXXXXXXXXX 158
           V++W+   G C+      ++ V  + +     L+  AG D+++ ++D             
Sbjct: 363 VRIWDVETGACLRQNNIPQNLVTDVKWLPGSHLIIQAGEDKEVRIYDSRTLGIVRSFTKK 542

Query: 159 XXXXXXXG-NKDSIYSLAM-NQLGTIIVSGSTEKVLRVWDPRTCAKLMKLKGHTDNVKAL 216
                      D  + L   N  G        E  L  W     +   + KGH + ++A 
Sbjct: 543 QYIQMSCDVTADGQFCLTCSNGFG----GNGCEATL--WQLSDGSIQNEFKGHREAIEAC 704

Query: 217 LL---HRDGTQCLSGSSDGTIRLWSLGQQRCIATYRVHDEG 254
           L    ++D T   + S D ++R+W++  + C+        G
Sbjct: 705 LFLPSNQDMTLIATASRDCSVRVWNMFTKECVCEQNFEGTG 827

 Score = 39.3 bits (90), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 29/125 (23%), Positives = 54/125 (43%)
 Frame = +3

Query: 183 IVSGSTEKVLRVWDPRTCAKLMKLKGHTDNVKALLLHRDGTQCLSGSSDGTIRLWSLGQQ 242
           + S S +K +++W       +    GH   V A+ L+ D T   SGS D T+R+W +   
Sbjct: 210 MFSASRDKTIKMWQRGNSHSIRDFIGHDMVVTAIHLNTDNTLLCSGSRDNTVRIWDVETG 389

Query: 243 RCIATYRVHDEGVWALQVNDAFTHVYSGGRDRKIYCTDLRNPDIRVLICEEKAPVLKMEL 302
            C+    +    V  ++       +   G D+++   D R   + ++    K   ++M  
Sbjct: 390 ACLRQNNIPQNLVTDVKWLPGSHLIIQAGEDKEVRIYDSRT--LGIVRSFTKKQYIQMSC 563

Query: 303 DRSAD 307
           D +AD
Sbjct: 564 DVTAD 578

 Score = 37.4 bits (85), Expect = 0.019,   Method: Compositional matrix adjust.
 Identities = 25/95 (26%), Positives = 42/95 (44%)
 Frame = +3

Query: 182 IIVSGSTEKVLRVWDPRTCAKLMKLKGHTDNVKALLLHRDGTQCLSGSSDGTIRLWSLGQ 241
           + +SGS +K + ++D +      +  GH   +  +          S S D TI++W  G 
Sbjct: 81  LCLSGSKDKSVVLYDYQNGRLEDRWTGHDREITKVCYGASCNGMFSASRDKTIKMWQRGN 260

Query: 242 QRCIATYRVHDEGVWALQVNDAFTHVYSGGRDRKI 276
              I  +  HD  V A+ +N   T + SG RD  +
Sbjct: 261 SHSIRDFIGHDMVVTAIHLNTDNTLLCSGSRDNTV 365

 Score = 31.2 bits (69), Expect = 1.4,   Method: Compositional matrix adjust.
 Identities = 24/113 (21%), Positives = 44/113 (38%)
 Frame = +3

Query: 91  ISASSDTTVKVWNAHKGFCMSTLRTHKDYVKALAYAKDKELVASAGLDRQIFLWDXXXXX 150
           +S S D +V +++   G        H   +  + Y      + SA  D+ I +W      
Sbjct: 87  LSGSKDKSVVLYDYQNGRLEDRWTGHDREITKVCYGASCNGMFSASRDKTIKMWQRGNSH 266

Query: 151 XXXXXXXXXXXXXXXGNKDSIYSLAMNQLGTIIVSGSTEKVLRVWDPRTCAKL 203
                          G+   + ++ +N   T++ SGS +  +R+WD  T A L
Sbjct: 267 SIRDFI---------GHDMVVTAIHLNTDNTLLCSGSRDNTVRIWDVETGACL 398
>03156
          Length = 1014

 Score = 51.6 bits (122), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 48/221 (21%), Positives = 86/221 (38%), Gaps = 6/221 (2%)
 Frame = +1

Query: 40  PALNRLFTAGRDSIIRIWSV-NQHKQDPYIASMEHHTDWVNDVVLCCNGKTLISASSDTT 98
            + N +F+A RD  I++W   N H    +I     H   V  + L  +   L S S D T
Sbjct: 85  ASCNGMFSASRDKTIKMWQRGNSHSIRDFIG----HDMVVTAIHLNTDNTLLCSGSRDNT 252

Query: 99  VKVWNAHKGFCMSTLRTHKDYVKALAYAKDKELVASAGLDRQIFLWDXXXXXXXXXXXXX 158
           V++W+   G C+      ++ V  + +     L+  AG D+++ ++D             
Sbjct: 253 VRIWDVETGACLRQNNIPQNLVTDVKWLPGSHLIIQAGEDKEVRIYDSRTLGIVRSFTKK 432

Query: 159 XXXXXXXG-NKDSIYSLAM-NQLGTIIVSGSTEKVLRVWDPRTCAKLMKLKGHTDNVKAL 216
                      D  + L   N  G        E  L  W     +   + KGH + ++A 
Sbjct: 433 QYIQMSCDVTADGQFCLTCSNGFG----GNGCEATL--WQLSDGSIQNEFKGHREAIEAC 594

Query: 217 LL---HRDGTQCLSGSSDGTIRLWSLGQQRCIATYRVHDEG 254
           L    ++D T   + S D ++R+W++  + C+        G
Sbjct: 595 LFLPSNQDMTLIATASRDCSVRVWNMFTKECVCEQNFEGTG 717

 Score = 38.9 bits (89), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 29/125 (23%), Positives = 54/125 (43%)
 Frame = +1

Query: 183 IVSGSTEKVLRVWDPRTCAKLMKLKGHTDNVKALLLHRDGTQCLSGSSDGTIRLWSLGQQ 242
           + S S +K +++W       +    GH   V A+ L+ D T   SGS D T+R+W +   
Sbjct: 100 MFSASRDKTIKMWQRGNSHSIRDFIGHDMVVTAIHLNTDNTLLCSGSRDNTVRIWDVETG 279

Query: 243 RCIATYRVHDEGVWALQVNDAFTHVYSGGRDRKIYCTDLRNPDIRVLICEEKAPVLKMEL 302
            C+    +    V  ++       +   G D+++   D R   + ++    K   ++M  
Sbjct: 280 ACLRQNNIPQNLVTDVKWLPGSHLIIQAGEDKEVRIYDSRT--LGIVRSFTKKQYIQMSC 453

Query: 303 DRSAD 307
           D +AD
Sbjct: 454 DVTAD 468

 Score = 33.1 bits (74), Expect = 0.41,   Method: Compositional matrix adjust.
 Identities = 20/69 (28%), Positives = 29/69 (42%)
 Frame = +1

Query: 208 GHTDNVKALLLHRDGTQCLSGSSDGTIRLWSLGQQRCIATYRVHDEGVWALQVNDAFTHV 267
           GH   +  +          S S D TI++W  G    I  +  HD  V A+ +N   T +
Sbjct: 49  GHDREITKVCYGASCNGMFSASRDKTIKMWQRGNSHSIRDFIGHDMVVTAIHLNTDNTLL 228

Query: 268 YSGGRDRKI 276
            SG RD  +
Sbjct: 229 CSGSRDNTV 255
>13278
          Length = 870

 Score = 51.2 bits (121), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 20/56 (35%), Positives = 37/56 (66%)
 Frame = +1

Query: 90  LISASSDTTVKVWNAHKGFCMSTLRTHKDYVKALAYAKDKELVASAGLDRQIFLWD 145
           L SAS D+TV++W   +G C+ TL  H++ V ++A++ D + +AS   D+ + +W+
Sbjct: 121 LASASFDSTVRLWEVERGLCLHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWN 288

 Score = 37.7 bits (86), Expect = 0.016,   Method: Compositional matrix adjust.
 Identities = 25/104 (24%), Positives = 46/104 (44%)
 Frame = +1

Query: 182 IIVSGSTEKVLRVWDPRTCAKLMKLKGHTDNVKALLLHRDGTQCLSGSSDGTIRLWSLGQ 241
           I+ S S +  +R+W+      L  L  H + V ++    DG    SGS D  + +W++  
Sbjct: 118 ILASASFDSTVRLWEVERGLCLHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNVQT 297

Query: 242 QRCIATYRVHDEGVWALQVNDAFTHVYSGGRDRKIYCTDLRNPD 285
              + +Y+    G++ +  N     V +   D  ++  DLR  D
Sbjct: 298 GSLVHSYK-GTGGIFEVCWNHRGDKVGASASDGSVFVLDLRK*D 426

 Score = 34.7 bits (78), Expect = 0.12,   Method: Compositional matrix adjust.
 Identities = 23/104 (22%), Positives = 49/104 (47%)
 Frame = +1

Query: 131 LVASAGLDRQIFLWDXXXXXXXXXXXXXXXXXXXXGNKDSIYSLAMNQLGTIIVSGSTEK 190
           ++ASA  D  + LW+                     +++ +YS+A +  G  + SGS +K
Sbjct: 118 ILASASFDSTVRLWEVERGLCLHTLTK---------HQEPVYSVAFSPDGKYLASGSFDK 270

Query: 191 VLRVWDPRTCAKLMKLKGHTDNVKALLLHRDGTQCLSGSSDGTI 234
            + +W+ +T + +   KG T  +  +  +  G +  + +SDG++
Sbjct: 271 CVHIWNVQTGSLVHSYKG-TGGIFEVCWNHRGDKVGASASDGSV 399
>27465
          Length = 658

 Score = 50.4 bits (119), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 37/161 (22%), Positives = 63/161 (39%), Gaps = 11/161 (6%)
 Frame = -1

Query: 90  LISASSDTTVKVW----------NAHKGFCMSTLRTHKDYVKALAYAKDKELVASAGLDR 139
           LI+ S    VK W          + H  +    LR H   +  +A+ K      +   DR
Sbjct: 472 LITPSKQEHVKNWCFACRKTRPKDDHHFYLFKVLRAHILPLTNVAFNKSGSSFITGSYDR 293

Query: 140 QIFLWDXXXXXXXXXXXXXXXXXXXXGNKDSIYSLAMNQ-LGTIIVSGSTEKVLRVWDPR 198
              +WD                    G+++ +Y++A N   G  +++GS +K  ++W   
Sbjct: 292 TCKIWDTASAEELHTLE---------GHRNVVYAIAFNNPFGDKVITGSFDKTCKLWSTA 140

Query: 199 TCAKLMKLKGHTDNVKALLLHRDGTQCLSGSSDGTIRLWSL 239
                  L+GHT  +  +  +   T   +GS D T RLW +
Sbjct: 139 DGKCYHTLRGHTAEIVCVSFNPSSTLIATGSMDTTCRLWDV 17

 Score = 43.9 bits (102), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 27/106 (25%), Positives = 47/106 (44%), Gaps = 3/106 (2%)
 Frame = -1

Query: 43  NRLFTAGRDSIIRIWSVNQHKQDPYIASMEHHTDWVNDVVLCCN---GKTLISASSDTTV 99
           +   T   D   +IW     ++   + ++E H + V  +    N   G  +I+ S D T 
Sbjct: 322 SSFITGSYDRTCKIWDTASAEE---LHTLEGHRNVVYAIAF--NNPFGDKVITGSFDKTC 158

Query: 100 KVWNAHKGFCMSTLRTHKDYVKALAYAKDKELVASAGLDRQIFLWD 145
           K+W+   G C  TLR H   +  +++     L+A+  +D    LWD
Sbjct: 157 KLWSTADGKCYHTLRGHTAEIVCVSFNPSSTLIATGSMDTTCRLWD 20
>15780
          Length = 735

 Score = 50.1 bits (118), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 24/58 (41%), Positives = 35/58 (60%)
 Frame = -1

Query: 88  KTLISASSDTTVKVWNAHKGFCMSTLRTHKDYVKALAYAKDKELVASAGLDRQIFLWD 145
           K L +A +D TV VW+   G  ++ L  H D V AL +++D  ++AS G+D  I LWD
Sbjct: 735 KYLSTAGADHTVIVWDIASGTAVAHLTAHTDTVYALCFSRDGTVLASGGMDNSIRLWD 562

 Score = 46.6 bits (109), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 22/48 (45%), Positives = 26/48 (54%)
 Frame = -1

Query: 194 VWDPRTCAKLMKLKGHTDNVKALLLHRDGTQCLSGSSDGTIRLWSLGQ 241
           VWD  +   +  L  HTD V AL   RDGT   SG  D +IRLW L +
Sbjct: 696 VWDIASGTAVAHLTAHTDTVYALCFSRDGTVLASGGMDNSIRLWDLAR 553

 Score = 34.3 bits (77), Expect = 0.17,   Method: Compositional matrix adjust.
 Identities = 17/74 (22%), Positives = 36/74 (48%)
 Frame = -1

Query: 132 VASAGLDRQIFLWDXXXXXXXXXXXXXXXXXXXXGNKDSIYSLAMNQLGTIIVSGSTEKV 191
           +++AG D  + +WD                     + D++Y+L  ++ GT++ SG  +  
Sbjct: 729 LSTAGADHTVIVWDIASGTAVAHLT---------AHTDTVYALCFSRDGTVLASGGMDNS 577

Query: 192 LRVWDPRTCAKLMK 205
           +R+WD    A++M+
Sbjct: 576 IRLWD---LARVME 544

 Score = 31.6 bits (70), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 16/59 (27%), Positives = 28/59 (47%)
 Frame = -1

Query: 45  LFTAGRDSIIRIWSVNQHKQDPYIASMEHHTDWVNDVVLCCNGKTLISASSDTTVKVWN 103
           L TAG D  + +W +        +A +  HTD V  +    +G  L S   D ++++W+
Sbjct: 729 LSTAGADHTVIVWDIASGTA---VAHLTAHTDTVYALCFSRDGTVLASGGMDNSIRLWD 562

 Score = 29.6 bits (65), Expect = 4.0,   Method: Compositional matrix adjust.
 Identities = 19/70 (27%), Positives = 31/70 (44%)
 Frame = -1

Query: 227 SGSSDGTIRLWSLGQQRCIATYRVHDEGVWALQVNDAFTHVYSGGRDRKIYCTDLRNPDI 286
           +  +D T+ +W +     +A    H + V+AL  +   T + SGG D  I   DL     
Sbjct: 723 TAGADHTVIVWDIASGTAVAHLTAHTDTVYALCFSRDGTVLASGGMDNSIRLWDLAR--- 553

Query: 287 RVLICEEKAP 296
              + EE+ P
Sbjct: 552 ---VMEEQDP 532
>18981
          Length = 407

 Score = 48.9 bits (115), Expect = 7e-06,   Method: Compositional matrix adjust.
 Identities = 26/88 (29%), Positives = 50/88 (56%)
 Frame = -2

Query: 176 MNQLGTIIVSGSTEKVLRVWDPRTCAKLMKLKGHTDNVKALLLHRDGTQCLSGSSDGTIR 235
           ++ L  +I+S +T++ LRVW  +    L  L+GH D+V+ + ++  G + +SGS D T+ 
Sbjct: 400 IHLLDNMIISAATDRTLRVWCLKNTCLLHTLRGHNDDVECVCIY--GRRVVSGSWDKTLI 227

Query: 236 LWSLGQQRCIATYRVHDEGVWALQVNDA 263
           +W +   R +     H E + A+Q ++ 
Sbjct: 226 VWEVDTGRPVHQLHGHTEAITAVQFDEG 143

 Score = 48.1 bits (113), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 28/82 (34%), Positives = 47/82 (57%)
 Frame = -2

Query: 166 GNKDSIYSLAMNQLGTIIVSGSTEKVLRVWDPRTCAKLMKLKGHTDNVKALLLHRDGTQC 225
           G+ D +  + +   G  +VSGS +K L VW+  T   + +L GHT+ + A+    D  + 
Sbjct: 304 GHNDDVECVCI--YGRRVVSGSWDKTLIVWEVDTGRPVHQLHGHTEAITAVQF--DEGKA 137

Query: 226 LSGSSDGTIRLWSLGQQRCIAT 247
           +SGS+DG +R W+L   +C+ T
Sbjct: 136 VSGSADGDVRTWALDTGQCLLT 71

 Score = 33.1 bits (74), Expect = 0.36,   Method: Compositional matrix adjust.
 Identities = 17/56 (30%), Positives = 30/56 (53%)
 Frame = -2

Query: 90  LISASSDTTVKVWNAHKGFCMSTLRTHKDYVKALAYAKDKELVASAGLDRQIFLWD 145
           +ISA++D T++VW       + TLR H D V+ +     +  V S   D+ + +W+
Sbjct: 379 IISAATDRTLRVWCLKNTCLLHTLRGHNDDVECVCIYGRR--VVSGSWDKTLIVWE 218
>17266
          Length = 480

 Score = 47.8 bits (112), Expect = 1e-05,   Method: Composition-based stats.
 Identities = 32/144 (22%), Positives = 57/144 (39%)
 Frame = -1

Query: 88  KTLISASSDTTVKVWNAHKGFCMSTLRTHKDYVKALAYAKDKELVASAGLDRQIFLWDXX 147
           +T +S + D + K+W+   G C  T   H+  + A+ Y  +    A+   D    L+D  
Sbjct: 420 RTFVSGACDASAKLWDVRDGMCKQTFSGHESDINAITYFPNGHAFATGSDDATCRLFDIR 241

Query: 148 XXXXXXXXXXXXXXXXXXGNKDSIYSLAMNQLGTIIVSGSTEKVLRVWDPRTCAKLMKLK 207
                                  I S+A ++ G +++ G  +    +WD     +   L 
Sbjct: 240 ADQEIGMYSHDNIIC-------GITSVAFSKSGRLLLGGYDDFNCNIWDVLKQERTGVLA 82

Query: 208 GHTDNVKALLLHRDGTQCLSGSSD 231
           GH + V  L +  DG+   +GS D
Sbjct: 81  GHDNRVSCLGVTEDGSAVATGSWD 10

 Score = 35.4 bits (80), Expect = 0.071,   Method: Composition-based stats.
 Identities = 20/69 (28%), Positives = 32/69 (46%)
 Frame = -1

Query: 184 VSGSTEKVLRVWDPRTCAKLMKLKGHTDNVKALLLHRDGTQCLSGSSDGTIRLWSLGQQR 243
           VSG+ +   ++WD R         GH  ++ A+    +G    +GS D T RL+ +   +
Sbjct: 411 VSGACDASAKLWDVRDGMCKQTFSGHESDINAITYFPNGHAFATGSDDATCRLFDIRADQ 232

Query: 244 CIATYRVHD 252
            I  Y  HD
Sbjct: 231 EIGMYS-HD 208
>12960
          Length = 550

 Score = 47.8 bits (112), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 28/122 (22%), Positives = 52/122 (42%)
 Frame = +2

Query: 78  VNDVVLCCNGKTLISASSDTTVKVWNAHKGFCMSTLRTHKDYVKALAYAKDKELVASAGL 137
           V  V    + +  ++  SD +VK+WN H+   + T   H   V     + D   + S G+
Sbjct: 182 VRAVRFSVDSRYCMTCGSDKSVKLWNPHRELFLKTYIGHGHEVLDAQGSGDNSQICSGGI 361

Query: 138 DRQIFLWDXXXXXXXXXXXXXXXXXXXXGNKDSIYSLAMNQLGTIIVSGSTEKVLRVWDP 197
           D+ + L+D                     +  ++  +  N+  T+I+SGS +  +R WD 
Sbjct: 362 DKTVVLFDVASGQALRKYRD---------HAGTVNCVKFNEESTVILSGSLDNTVRAWDT 514

Query: 198 RT 199
           R+
Sbjct: 515 RS 520

 Score = 39.3 bits (90), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 27/126 (21%), Positives = 51/126 (40%)
 Frame = +2

Query: 112 TLRTHKDYVKALAYAKDKELVASAGLDRQIFLWDXXXXXXXXXXXXXXXXXXXXGNKDSI 171
           T+   +  V+A+ ++ D     + G D+ + LW+                    G+   +
Sbjct: 158 TINCKQQAVRAVRFSVDSRYCMTCGSDKSVKLWNPHRELFLKTYI---------GHGHEV 310

Query: 172 YSLAMNQLGTIIVSGSTEKVLRVWDPRTCAKLMKLKGHTDNVKALLLHRDGTQCLSGSSD 231
                +   + I SG  +K + ++D  +   L K + H   V  +  + + T  LSGS D
Sbjct: 311 LDAQGSGDNSQICSGGIDKTVVLFDVASGQALRKYRDHAGTVNCVKFNEESTVILSGSLD 490

Query: 232 GTIRLW 237
            T+R W
Sbjct: 491 NTVRAW 508

 Score = 33.1 bits (74), Expect = 0.38,   Method: Compositional matrix adjust.
 Identities = 18/69 (26%), Positives = 35/69 (50%)
 Frame = +2

Query: 213 VKALLLHRDGTQCLSGSSDGTIRLWSLGQQRCIATYRVHDEGVWALQVNDAFTHVYSGGR 272
           V+A+    D   C++  SD +++LW+  ++  + TY  H   V   Q +   + + SGG 
Sbjct: 182 VRAVRFSVDSRYCMTCGSDKSVKLWNPHRELFLKTYIGHGHEVLDAQGSGDNSQICSGGI 361

Query: 273 DRKIYCTDL 281
           D+ +   D+
Sbjct: 362 DKTVVLFDV 388
>02090
          Length = 1841

 Score = 47.4 bits (111), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 28/95 (29%), Positives = 43/95 (45%), Gaps = 2/95 (2%)
 Frame = -3

Query: 190  KVLRVWDPRTCAKLMK--LKGHTDNVKALLLHRDGTQCLSGSSDGTIRLWSLGQQRCIAT 247
              L +WD  T    +K  L        AL +  DG  C S  SDG I +W L  Q  +  
Sbjct: 1692 STLSIWDLATPTPRIKAELTSSAPACYALAISPDGKVCFSCCSDGNIAVWDLHNQTLVRQ 1513

Query: 248  YRVHDEGVWALQVNDAFTHVYSGGRDRKIYCTDLR 282
            ++ H +G   + ++   T +++GG D  +   DLR
Sbjct: 1512 FQGHTDGASCIDISPDGTKLWTGGLDNTVRSWDLR 1408

 Score = 45.4 bits (106), Expect = 8e-05,   Method: Compositional matrix adjust.
 Identities = 22/74 (29%), Positives = 39/74 (52%)
 Frame = -3

Query: 170  SIYSLAMNQLGTIIVSGSTEKVLRVWDPRTCAKLMKLKGHTDNVKALLLHRDGTQCLSGS 229
            + Y+LA++  G +  S  ++  + VWD      + + +GHTD    + +  DGT+  +G 
Sbjct: 1620 ACYALAISPDGKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISPDGTKLWTGG 1441

Query: 230  SDGTIRLWSLGQQR 243
             D T+R W L + R
Sbjct: 1440 LDNTVRSWDLREGR 1399

 Score = 33.9 bits (76), Expect = 0.22,   Method: Compositional matrix adjust.
 Identities = 16/60 (26%), Positives = 26/60 (43%)
 Frame = -3

Query: 86   NGKTLISASSDTTVKVWNAHKGFCMSTLRTHKDYVKALAYAKDKELVASAGLDRQIFLWD 145
            +GK   S  SD  + VW+ H    +   + H D    +  + D   + + GLD  +  WD
Sbjct: 1593 DGKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISPDGTKLWTGGLDNTVRSWD 1414
>26939
          Length = 388

 Score = 46.6 bits (109), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 20/59 (33%), Positives = 34/59 (57%)
 Frame = +2

Query: 87  GKTLISASSDTTVKVWNAHKGFCMSTLRTHKDYVKALAYAKDKELVASAGLDRQIFLWD 145
           GK L+SAS D T++VW+     CM TL  H+ +  ++ + K    V S  +D+ + +W+
Sbjct: 2   GKYLVSASDDKTIRVWDLRNKRCMKTLYAHQHFCTSIDFHKAHPYVISGSVDQTVKVWE 178

 Score = 40.0 bits (92), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 19/58 (32%), Positives = 30/58 (51%)
 Frame = +2

Query: 180 GTIIVSGSTEKVLRVWDPRTCAKLMKLKGHTDNVKALLLHRDGTQCLSGSSDGTIRLW 237
           G  +VS S +K +RVWD R    +  L  H     ++  H+     +SGS D T+++W
Sbjct: 2   GKYLVSASDDKTIRVWDLRNKRCMKTLYAHQHFCTSIDFHKAHPYVISGSVDQTVKVW 175

 Score = 37.4 bits (85), Expect = 0.020,   Method: Compositional matrix adjust.
 Identities = 18/55 (32%), Positives = 28/55 (50%)
 Frame = +2

Query: 222 GTQCLSGSSDGTIRLWSLGQQRCIATYRVHDEGVWALQVNDAFTHVYSGGRDRKI 276
           G   +S S D TIR+W L  +RC+ T   H     ++  + A  +V SG  D+ +
Sbjct: 2   GKYLVSASDDKTIRVWDLRNKRCMKTLYAHQHFCTSIDFHKAHPYVISGSVDQTV 166
>17602
          Length = 481

 Score = 46.6 bits (109), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 21/55 (38%), Positives = 31/55 (56%)
 Frame = +3

Query: 193 RVWDPRTCAKLMKLKGHTDNVKALLLHRDGTQCLSGSSDGTIRLWSLGQQRCIAT 247
           R+WD +T   L  L  H+D V A+  +RDG+  +S S DG  R+W     +C+ T
Sbjct: 3   RIWDVKTGKCLKTLPAHSDPVTAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLXT 167

 Score = 46.2 bits (108), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 32/120 (26%), Positives = 58/120 (48%), Gaps = 5/120 (4%)
 Frame = +3

Query: 167 NKDSIYSLAMNQLGTIIVSGSTEKVLRVWDPRTCAKLMKLKGHTDN--VKALLLHRDGTQ 224
           + D + ++  N+ G++IVS S + + R+WD  +   L  L    DN  V  +    +G  
Sbjct: 51  HSDPVTAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLXTLI-DDDNPPVSFVKFSPNGKY 227

Query: 225 CLSGSSDGTIRLWSLGQQRCIATYRVHDEGVWALQVNDAFTH---VYSGGRDRKIYCTDL 281
            L+ + D T++LW   + +C+ TY  H    + +  N + T    + SG  D  +Y  +L
Sbjct: 228 ILAATLDNTLKLWDYSKGKCLKTYVGHRNEKYCIFANFSVTGGKWIVSGSEDNMVYIWNL 407

 Score = 45.4 bits (106), Expect = 8e-05,   Method: Compositional matrix adjust.
 Identities = 32/146 (21%), Positives = 59/146 (40%), Gaps = 3/146 (2%)
 Frame = +3

Query: 100 KVWNAHKGFCMSTLRTHKDYVKALAYAKDKELVASAGLDRQIFLWDXXXXXXXXXXXXXX 159
           ++W+   G C+ TL  H D V A+ + +D  L+ S+  D    +WD              
Sbjct: 3   RIWDVKTGKCLKTLPAHSDPVTAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLXTLIDD- 179

Query: 160 XXXXXXGNKDSIYSLAMNQLGTIIVSGSTEKVLRVWDPRTCAKLMKLKGHTDNVKALLLH 219
                  +   +  +  +  G  I++ + +  L++WD      L    GH +    +  +
Sbjct: 180 -------DNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYVGHRNEKYCIFAN 338

Query: 220 ---RDGTQCLSGSSDGTIRLWSLGQQ 242
                G   +SGS D  + +W+L  Q
Sbjct: 339 FSVTGGKWIVSGSEDNMVYIWNLLDQ 416

 Score = 43.1 bits (100), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 41/172 (23%), Positives = 73/172 (42%), Gaps = 4/172 (2%)
 Frame = +3

Query: 55  RIWSVNQHKQDPYIASMEHHTDWVNDVVLCCNGKTLISASSDTTVKVWNAHKGFCMSTLR 114
           RIW V   K    + ++  H+D V  V    +G  ++S+S D   ++W+   G C+ TL 
Sbjct: 3   RIWDVKTGKC---LKTLPAHSDPVTAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLXTLI 173

Query: 115 THKD-YVKALAYAKDKELVASAGLDRQIFLWDXXXXXXXXXXXXXXXXXXXXGNKDSIYS 173
              +  V  + ++ + + + +A LD  + LWD                    G+++  Y 
Sbjct: 174 DDDNPPVSFVKFSPNGKYILAATLDNTLKLWD---------YSKGKCLKTYVGHRNEKYC 326

Query: 174 LAMN---QLGTIIVSGSTEKVLRVWDPRTCAKLMKLKGHTDNVKALLLHRDG 222
           +  N     G  IVSGS + ++ +W+         L    D+ +A   HR G
Sbjct: 327 IFANFSVTGGKWIVSGSEDNMVYIWN---------LLDQGDSTEATGSHRRG 455

 Score = 37.0 bits (84), Expect = 0.024,   Method: Compositional matrix adjust.
 Identities = 25/116 (21%), Positives = 53/116 (45%), Gaps = 3/116 (2%)
 Frame = +3

Query: 33  VNALQLDPALNRLFTAGRDSIIRIWSVNQHKQDPYIASMEHHTDWVNDVVLCCNGKTLIS 92
           V A+  +   + + ++  D + RIW     +       ++     V+ V    NGK +++
Sbjct: 63  VTAVHFNRDGSLIVSSSYDGLCRIWDTASGQC--LXTLIDDDNPPVSFVKFSPNGKYILA 236

Query: 93  ASSDTTVKVWNAHKGFCMSTLRTHKD---YVKALAYAKDKELVASAGLDRQIFLWD 145
           A+ D T+K+W+  KG C+ T   H++    + A       + + S   D  +++W+
Sbjct: 237 ATLDNTLKLWDYSKGKCLKTYVGHRNEKYCIFANFSVTGGKWIVSGSEDNMVYIWN 404
>21105
          Length = 650

 Score = 46.6 bits (109), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 26/96 (27%), Positives = 47/96 (48%), Gaps = 4/96 (4%)
 Frame = +1

Query: 182 IIVSGSTEKVLRVWDPRTCAKLMKLKGHTDNVKALLLHRDGTQCLSGSSDGTIRLWSLGQ 241
           I ++   ++ +R +D  T   +  +  H D+V +L +  +G   LSGS D +IRLW+L  
Sbjct: 106 ITITAHEDRHIRFFDNNTGKLIHAMVAHLDSVTSLAVDPNGLYLLSGSHDCSIRLWNLDS 285

Query: 242 QRCIATYRVH----DEGVWALQVNDAFTHVYSGGRD 273
           + C+     H    DE +  +  +    ++ S G D
Sbjct: 286 KTCVQEITSHRKKFDESIHDVAFHPQKPYIASAGAD 393

 Score = 46.2 bits (108), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 30/103 (29%), Positives = 49/103 (47%), Gaps = 4/103 (3%)
 Frame = +1

Query: 40  PALNRLFTAGRDSIIRIWSVNQHKQDPYIASMEHHTDWVNDVVLCCNGKTLISASSDTTV 99
           P +    TA  D  IR +  N  K    I +M  H D V  + +  NG  L+S S D ++
Sbjct: 94  PTMPITITAHEDRHIRFFDNNTGK---LIHAMVAHLDSVTSLAVDPNGLYLLSGSHDCSI 264

Query: 100 KVWNAHKGFCMSTLRTHK----DYVKALAYAKDKELVASAGLD 138
           ++WN     C+  + +H+    + +  +A+   K  +ASAG D
Sbjct: 265 RLWNLDSKTCVQEITSHRKKFDESIHDVAFHPQKPYIASAGAD 393

 Score = 29.6 bits (65), Expect = 3.9,   Method: Compositional matrix adjust.
 Identities = 14/36 (38%), Positives = 24/36 (66%), Gaps = 2/36 (5%)
 Frame = +1

Query: 169 DSIYSLAMNQLGTIIVSGSTEKVLRVW--DPRTCAK 202
           DS+ SLA++  G  ++SGS +  +R+W  D +TC +
Sbjct: 193 DSVTSLAVDPNGLYLLSGSHDCSIRLWNLDSKTCVQ 300
>19498
          Length = 903

 Score = 45.8 bits (107), Expect = 6e-05,   Method: Compositional matrix adjust.
 Identities = 46/183 (25%), Positives = 68/183 (37%), Gaps = 23/183 (12%)
 Frame = -1

Query: 68  IASMEHHTDWVNDVVLCCNGKTLISASSDTTVKVWNAHKGF-----------------CM 110
           +  M+ H   VN V    NGK L S   D  + +W   +GF                  +
Sbjct: 807 LCQMDSHLGCVNCVRWSENGKFLASGGDDKLIMIWQISRGFGSGKSFGSNVTILEHWRSV 628

Query: 111 STLRTHKDYVKALAYAKDKELVASAGLDRQIFLWDXXXXXXXXXXXXXXXXXXXXGNKDS 170
           +TLR H   V  LA++     +AS  +D  I +W+                    G+   
Sbjct: 627 ATLRGHAGDVLDLAWSPQDLWLASCSVDNTIVVWN--------ALKFSEQVAVIRGHAGM 472

Query: 171 IYSLAMNQLGTIIVSGSTEKVLRV-----WDPRTCAK-LMKLKGHTDNVKALLLHRDGTQ 224
           +  +  + +G  + S S +K LRV     W   TC K   K  G T +V  L    DG  
Sbjct: 471 VKGVTWDPVGRYLASQSDDKTLRVWRTSDWKEETCVKSCFKECGGTTHVLRLNWSPDGNH 292

Query: 225 CLS 227
            +S
Sbjct: 291 VVS 283

 Score = 31.6 bits (70), Expect = 0.97,   Method: Compositional matrix adjust.
 Identities = 26/137 (18%), Positives = 53/137 (38%), Gaps = 9/137 (6%)
 Frame = -1

Query: 110 MSTLRTHKDYVKALAYAKDKELVASAGLDRQIFLWDXXXXXXXXXXXXXX--------XX 161
           +  + +H   V  + ++++ + +AS G D+ I +W                         
Sbjct: 807 LCQMDSHLGCVNCVRWSENGKFLASGGDDKLIMIWQISRGFGSGKSFGSNVTILEHWRSV 628

Query: 162 XXXXGNKDSIYSLAMNQLGTIIVSGSTEKVLRVWDP-RTCAKLMKLKGHTDNVKALLLHR 220
               G+   +  LA +     + S S +  + VW+  +   ++  ++GH   VK +    
Sbjct: 627 ATLRGHAGDVLDLAWSPQDLWLASCSVDNTIVVWNALKFSEQVAVIRGHAGMVKGVTWDP 448

Query: 221 DGTQCLSGSSDGTIRLW 237
            G    S S D T+R+W
Sbjct: 447 VGRYLASQSDDKTLRVW 397
>01462
          Length = 995

 Score = 45.4 bits (106), Expect = 7e-05,   Method: Compositional matrix adjust.
 Identities = 21/71 (29%), Positives = 44/71 (61%), Gaps = 2/71 (2%)
 Frame = +2

Query: 171 IYSLAMNQ-LGTI-IVSGSTEKVLRVWDPRTCAKLMKLKGHTDNVKALLLHRDGTQCLSG 228
           + S+A+++ +GT  + +G+ ++ + VWD      L  ++GH D +  +++  D  +C+S 
Sbjct: 200 VNSIAVDEKMGTRRLYAGAGDRKIHVWDIEAGQYLNAMEGHKDYIHKVVMKNDAQECVSA 379

Query: 229 SSDGTIRLWSL 239
           S DGT+R+W +
Sbjct: 380 SEDGTVRMWDI 412

 Score = 43.1 bits (100), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 22/78 (28%), Positives = 44/78 (56%), Gaps = 2/78 (2%)
 Frame = +2

Query: 28  YNRNGVNALQLDPALN--RLFTAGRDSIIRIWSVNQHKQDPYIASMEHHTDWVNDVVLCC 85
           ++   VN++ +D  +   RL+    D  I +W +   +   Y+ +ME H D+++ VV+  
Sbjct: 185 FSNAEVNSIAVDEKMGTRRLYAGAGDRKIHVWDIEAGQ---YLNAMEGHKDYIHKVVMKN 355

Query: 86  NGKTLISASSDTTVKVWN 103
           + +  +SAS D TV++W+
Sbjct: 356 DAQECVSASEDGTVRMWD 409

 Score = 36.2 bits (82), Expect = 0.050,   Method: Compositional matrix adjust.
 Identities = 15/58 (25%), Positives = 28/58 (48%)
 Frame = +2

Query: 88  KTLISASSDTTVKVWNAHKGFCMSTLRTHKDYVKALAYAKDKELVASAGLDRQIFLWD 145
           + L + + D  + VW+   G  ++ +  HKDY+  +    D +   SA  D  + +WD
Sbjct: 236 RRLYAGAGDRKIHVWDIEAGQYLNAMEGHKDYIHKVVMKNDAQECVSASEDGTVRMWD 409
>12806
          Length = 961

 Score = 45.4 bits (106), Expect = 7e-05,   Method: Compositional matrix adjust.
 Identities = 28/90 (31%), Positives = 45/90 (50%), Gaps = 2/90 (2%)
 Frame = +3

Query: 36  LQLDPALNRLFTAGRDSIIRIWSVNQHKQDPYIASMEHHTDWVNDVVLCCNGKT--LISA 93
           +   P   ++ + GRD  ++IW++    +  Y      HTDWV  V    + K   ++SA
Sbjct: 309 VAFSPDNRQIASGGRDKNLKIWNI--MGECKYTVDANAHTDWVTCVRFHQDTKNPIVVSA 482

Query: 94  SSDTTVKVWNAHKGFCMSTLRTHKDYVKAL 123
           S+D T+KVW+ H     +T   HK  + AL
Sbjct: 483 SNDKTIKVWDNHTMTLKNTFVGHKAQITAL 572

 Score = 40.8 bits (94), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 38/192 (19%), Positives = 72/192 (37%), Gaps = 4/192 (2%)
 Frame = +3

Query: 115 THKDYVKALAYAKDKELVASAGLDRQIFLWDX-XXXXXXXXXXXXXXXXXXXGNKDSIYS 173
           T   Y + +     K  + S G D  I +WD                     G+   I  
Sbjct: 3   TTMQYGEQVVDGATKPFLISGGRDNNIIVWDL*PKKDGDEDQTWGVPRKTLTGHSHFISD 182

Query: 174 LAMNQLGTIIVSGSTEKVLRVWDPRTCAKLMKLKGHTDNVKALLLHRDGTQCLSGSSDGT 233
           LA++      +S S +  LR+WD +  +   +   HT +V  +    D  Q  SG  D  
Sbjct: 183 LALSADSRFALSSSWDATLRLWDIKKGSTTSRFINHTRDVLTVAFSPDNRQIASGGRDKN 362

Query: 234 IRLWS-LGQQRCIATYRVHDEGVWALQVNDAFTH--VYSGGRDRKIYCTDLRNPDIRVLI 290
           +++W+ +G+ +       H + V  ++ +    +  V S   D+ I   D     ++   
Sbjct: 363 LKIWNIMGECKYTVDANAHTDWVTCVRFHQDTKNPIVVSASNDKTIKVWDNHTMTLKNTF 542

Query: 291 CEEKAPVLKMEL 302
              KA +  +++
Sbjct: 543 VGHKAQITALDM 578

 Score = 39.7 bits (91), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 37/155 (23%), Positives = 67/155 (43%), Gaps = 4/155 (2%)
 Frame = +3

Query: 46  FTAGRDSIIRIWSVNQHKQDPYIASMEHHTDWVNDVVLCCNGKTLISASSDTTVKVWNAH 105
            ++  D+ +R+W +   K+    +   +HT  V  V    + + + S   D  +K+WN  
Sbjct: 213 LSSSWDATLRLWDI---KKGSTTSRFINHTRDVLTVAFSPDNRQIASGGRDKNLKIWNI- 380

Query: 106 KGFCMSTL--RTHKDYVKALAYAKDKE--LVASAGLDRQIFLWDXXXXXXXXXXXXXXXX 161
            G C  T+    H D+V  + + +D +  +V SA  D+ I +WD                
Sbjct: 381 MGECKYTVDANAHTDWVTCVRFHQDTKNPIVVSASNDKTIKVWD---------NHTMTLK 533

Query: 162 XXXXGNKDSIYSLAMNQLGTIIVSGSTEKVLRVWD 196
               G+K  I +L M+     +VSGS + +   W+
Sbjct: 534 NTFVGHKAQITALDMST--NYLVSGSKDGIAMTWN 632
>10162
          Length = 1629

 Score = 43.9 bits (102), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 38/157 (24%), Positives = 62/157 (39%), Gaps = 10/157 (6%)
 Frame = +3

Query: 90  LISASSDTTVKVWNAHKGFCMSTLRTHK--------DYVKALAYAKDKELVASAGLDRQI 141
           ++S  +D T KV+N   G   S              + V+++A+       A+A     +
Sbjct: 414 IMSGCADATAKVFNVSSGKLXSAFNCAASQDSQDKDNSVESVAFCPVSPYAATATNSGSV 593

Query: 142 FLWDXXXXXXXXXXXXXXXXXXXXGNKDSIYSLAMNQLGTIIVSGSTEKVLRVWDPRTCA 201
            +WD                     + + +  L  +    ++ +   + V+RVWD R+ A
Sbjct: 594 QVWDLPTSVARHSFQ----------HPEGVCKLQWSSSTALLYTACLDGVMRVWDARSGA 743

Query: 202 KLMKLKGHTDNVKALLLH--RDGTQCLSGSSDGTIRL 236
               L GH  N   L     RDGT  +SGS DGT R+
Sbjct: 744 SKAVLTGHARNSCILDFDVTRDGTCLVSGSEDGTARV 854
>37180
          Length = 681

 Score = 43.5 bits (101), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 25/70 (35%), Positives = 40/70 (57%), Gaps = 2/70 (2%)
 Frame = +1

Query: 182 IIVSGSTEKVLRVWDPRTCAKLMKL-KGHTDNVKALLLHRDGTQCLSGSSDGTIRLWSLG 240
           ++V+ S +   R+WD R  A L+ + +GHT  V + +    G + +SGS D T+R+W + 
Sbjct: 61  LVVTSSKDMTFRLWDFRDSALLVNVFQGHTQPVTSAVF-ASGDKVVSGSDDRTVRVWDMR 237

Query: 241 QQRC-IATYR 249
             R  IAT R
Sbjct: 238 NMRSPIATIR 267
>31864
          Length = 545

 Score = 43.5 bits (101), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 38/166 (22%), Positives = 60/166 (36%)
 Frame = +2

Query: 74  HTDWVNDVVLCCNGKTLISASSDTTVKVWNAHKGFCMSTLRTHKDYVKALAYAKDKELVA 133
           HT  +ND+ L  +G   ++AS DTT K++++    C+ T +T +    A        +V 
Sbjct: 47  HTGGINDMQLSKDGTMFVTASKDTTAKLFDSESLMCLKTYKTERPVNSAAISPILDHVVL 226

Query: 134 SAGLDRQIFLWDXXXXXXXXXXXXXXXXXXXXGNKDSIYSLAMNQLGTIIVSGSTEKVLR 193
             G D                                    AM    T   +G  +   R
Sbjct: 227 GGGQD------------------------------------AMEVTTTSTKAGKFDS--R 292

Query: 194 VWDPRTCAKLMKLKGHTDNVKALLLHRDGTQCLSGSSDGTIRLWSL 239
            +      +  +LKGH   + +L  H DG    SG  DG +R+ S 
Sbjct: 293 FFHLIYEEEFARLKGHFGPINSLAFHPDGKSYASGGEDGFVRVKSF 430

 Score = 33.9 bits (76), Expect = 0.20,   Method: Compositional matrix adjust.
 Identities = 22/78 (28%), Positives = 37/78 (47%), Gaps = 1/78 (1%)
 Frame = +2

Query: 195 WDPRTCAKLMKLK-GHTDNVKALLLHRDGTQCLSGSSDGTIRLWSLGQQRCIATYRVHDE 253
           WD R   K++     HT  +  + L +DGT  ++ S D T +L+      C+ TY+  + 
Sbjct: 2   WDVRKGQKVVDSGVDHTGGINDMQLSKDGTMFVTASKDTTAKLFDSESLMCLKTYKT-ER 178

Query: 254 GVWALQVNDAFTHVYSGG 271
            V +  ++    HV  GG
Sbjct: 179 PVNSAAISPILDHVVLGG 232
>21921
          Length = 1341

 Score = 43.5 bits (101), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 20/54 (37%), Positives = 29/54 (53%)
 Frame = -1

Query: 197 PRTCAKLMKLKGHTDNVKALLLHRDGTQCLSGSSDGTIRLWSLGQQRCIATYRV 250
           P    + +  KGHT  V+++     G   +SGS DGTIR W +   RC+ T +V
Sbjct: 522 PFPTTQALVYKGHTGIVRSICPDPTGQWLVSGSDDGTIRFWEVSSGRCMKTLQV 361
>03395
          Length = 2795

 Score = 43.1 bits (100), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 36/213 (16%), Positives = 84/213 (39%), Gaps = 5/213 (2%)
 Frame = +2

Query: 32  GVNALQLDPALNRLFTAGRDSIIRIWSV-----NQHKQDPYIASMEHHTDWVNDVVLCCN 86
           GV A+ +     +L + G +  +R+W +         +   +A+M+ H   V  + +  N
Sbjct: 2   GVTAIAVTSCGTKLVSGGGEGQVRVWDIVKDMLTGKTRGDLVANMKEHKGKVTAIQIHTN 181

Query: 87  GKTLISASSDTTVKVWNAHKGFCMSTLRTHKDYVKALAYAKDKELVASAGLDRQIFLWDX 146
            +  +SAS+D +  +W+       S +       K + +      + ++G D +I  W+ 
Sbjct: 182 DRCCVSASTDGSTIIWDLITNT-RSQIVLANTLFKCVCFGGKDLHILTSGTDHKIGYWEV 358

Query: 147 XXXXXXXXXXXXXXXXXXXGNKDSIYSLAMNQLGTIIVSGSTEKVLRVWDPRTCAKLMKL 206
                                  +I ++ +++ G  I++G  + +L++W           
Sbjct: 359 GDGGLLRELEGS--------QTGAINTIDIDRDGQTILTGGEDSLLKLWRYNEGEVTHTG 514

Query: 207 KGHTDNVKALLLHRDGTQCLSGSSDGTIRLWSL 239
            GH++ +    +  +    +SG  DG + +W  
Sbjct: 515 IGHSNQITKARICPNRHYIVSGGEDGALHIWKF 613

 Score = 40.0 bits (92), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 44/210 (20%), Positives = 77/210 (36%), Gaps = 10/210 (4%)
 Frame = +2

Query: 78  VNDVVLCCNGKTLISASSDTTVKVWNAHK--------GFCMSTLRTHKDYVKALAYAKDK 129
           V  + +   G  L+S   +  V+VW+  K        G  ++ ++ HK  V A+    + 
Sbjct: 5   VTAIAVTSCGTKLVSGGGEGQVRVWDIVKDMLTGKTRGDLVANMKEHKGKVTAIQIHTND 184

Query: 130 ELVASAGLDRQIFLWDXXXXXXXXXXXXXXXXXXX-XGNKDSIYSLAMNQLGTIIVSGST 188
               SA  D    +WD                     G KD            I+ SG+ 
Sbjct: 185 RCCVSASTDGSTIIWDLITNTRSQIVLANTLFKCVCFGGKDL----------HILTSGTD 334

Query: 189 EKVLRVWDPRTCAKLMKLKG-HTDNVKALLLHRDGTQCLSGSSDGTIRLWSLGQQRCIAT 247
            K+   W+      L +L+G  T  +  + + RDG   L+G  D  ++LW   +     T
Sbjct: 335 HKI-GYWEVGDGGLLRELEGSQTGAINTIDIDRDGQTILTGGEDSLLKLWRYNEGEVTHT 511

Query: 248 YRVHDEGVWALQVNDAFTHVYSGGRDRKIY 277
              H   +   ++     ++ SGG D  ++
Sbjct: 512 GIGHSNQITKARICPNRHYIVSGGEDGALH 601
>31474
          Length = 403

 Score = 42.0 bits (97), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 30/94 (31%), Positives = 44/94 (46%), Gaps = 2/94 (2%)
 Frame = -3

Query: 36  LQLDPALNRLFTAGRDSIIRIWSVNQHKQDPYIASMEHHTDWVNDVVLCCNGKTLISASS 95
           +  +P    L + G D II+IW              + HT  V  +     G  L SAS 
Sbjct: 287 VAWNPTGTLLASCGSDKIIKIWGKEGDNWVCKSTLTDAHTRTVRSLGWSPCGNYLSSASF 108

Query: 96  DTTVKVWNAHKG--FCMSTLRTHKDYVKALAYAK 127
           D T  VW+   G   C++TL  H++ VKA+A+A+
Sbjct: 107 DATTAVWSRKGGEFECIATLEGHENEVKAVAWAR 6

 Score = 39.7 bits (91), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 27/90 (30%), Positives = 43/90 (47%), Gaps = 6/90 (6%)
 Frame = -3

Query: 172 YSLAMNQLGTIIVSGSTEKVLRVW----DPRTCAKLMKLKGHTDNVKALLLHRDGTQCLS 227
           + +A N  GT++ S  ++K++++W    D   C   +    HT  V++L     G    S
Sbjct: 293 WCVAWNPTGTLLASCGSDKIIKIWGKEGDNWVCKSTLT-DAHTRTVRSLGWSPCGNYLSS 117

Query: 228 GSSDGTIRLWSL--GQQRCIATYRVHDEGV 255
            S D T  +WS   G+  CIAT   H+  V
Sbjct: 116 ASFDATTAVWSRKGGEFECIATLEGHENEV 27
>19863
          Length = 502

 Score = 42.0 bits (97), Expect = 9e-04,   Method: Compositional matrix adjust.
 Identities = 20/60 (33%), Positives = 35/60 (58%)
 Frame = +1

Query: 180 GTIIVSGSTEKVLRVWDPRTCAKLMKLKGHTDNVKALLLHRDGTQCLSGSSDGTIRLWSL 239
           G  +VSGS++  + VWD     + ++L+GH   V  +   +D    LS S+D T+R+W++
Sbjct: 7   GLQLVSGSSDMSIVVWDVENGVQKLRLQGHAGWVNDVHFSQDQCWLLSCSNDNTVRIWNI 186

 Score = 36.6 bits (83), Expect = 0.032,   Method: Compositional matrix adjust.
 Identities = 22/74 (29%), Positives = 35/74 (47%)
 Frame = +1

Query: 44  RLFTAGRDSIIRIWSVNQHKQDPYIASMEHHTDWVNDVVLCCNGKTLISASSDTTVKVWN 103
           +L +   D  I +W V    Q      ++ H  WVNDV    +   L+S S+D TV++WN
Sbjct: 13  QLVSGSSDMSIVVWDVENGVQK---LRLQGHAGWVNDVHFSQDQCWLLSCSNDNTVRIWN 183

Query: 104 AHKGFCMSTLRTHK 117
             +   +  +  HK
Sbjct: 184 IEESDQIPIVMEHK 225

 Score = 36.2 bits (82), Expect = 0.043,   Method: Compositional matrix adjust.
 Identities = 16/60 (26%), Positives = 32/60 (53%)
 Frame = +1

Query: 86  NGKTLISASSDTTVKVWNAHKGFCMSTLRTHKDYVKALAYAKDKELVASAGLDRQIFLWD 145
           +G  L+S SSD ++ VW+   G     L+ H  +V  + +++D+  + S   D  + +W+
Sbjct: 4   DGLQLVSGSSDMSIVVWDVENGVQKLRLQGHAGWVNDVHFSQDQCWLLSCSNDNTVRIWN 183
>11493
          Length = 535

 Score = 40.0 bits (92), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 27/101 (26%), Positives = 45/101 (44%), Gaps = 5/101 (4%)
 Frame = -2

Query: 181 TIIVSGSTEKVLRVWD-----PRTCAKLMKLKGHTDNVKALLLHRDGTQCLSGSSDGTIR 235
           T+IV G     L +WD     PR  A+L           AL +  D   C S  SDG I 
Sbjct: 297 TLIVGGEASN-LSIWDLASPTPRIKAELTS---AAPACYALAISPDSKVCFSCCSDGNIA 130

Query: 236 LWSLGQQRCIATYRVHDEGVWALQVNDAFTHVYSGGRDRKI 276
           +W L  +  +  ++ H +G   + ++   + +++GG D  +
Sbjct: 129 VWDLHNEILVRQFQGHTDGASCIDISPDGSRLWTGGLDNTV 7

 Score = 35.0 bits (79), Expect = 0.093,   Method: Compositional matrix adjust.
 Identities = 22/118 (18%), Positives = 47/118 (39%)
 Frame = -2

Query: 118 DYVKALAYAKDKELVASAGLDRQIFLWDXXXXXXXXXXXXXXXXXXXXGNKDSIYSLAMN 177
           +Y++++    D   +   G    + +WD                        + Y+LA++
Sbjct: 336 NYIRSVKLLPDGRTLIVGGEASNLSIWDLASPTPRIKAELTSA-------APACYALAIS 178

Query: 178 QLGTIIVSGSTEKVLRVWDPRTCAKLMKLKGHTDNVKALLLHRDGTQCLSGSSDGTIR 235
               +  S  ++  + VWD      + + +GHTD    + +  DG++  +G  D T+R
Sbjct: 177 PDSKVCFSCCSDGNIAVWDLHNEILVRQFQGHTDGASCIDISPDGSRLWTGGLDNTVR 4

 Score = 32.7 bits (73), Expect = 0.44,   Method: Compositional matrix adjust.
 Identities = 24/112 (21%), Positives = 43/112 (38%), Gaps = 1/112 (0%)
 Frame = -2

Query: 31  NGVNALQLDPALNRLFTAGRDSIIRIWSVNQHKQDPYI-ASMEHHTDWVNDVVLCCNGKT 89
           N + +++L P    L   G  S + IW +      P I A +         + +  + K 
Sbjct: 336 NYIRSVKLLPDGRTLIVGGEASNLSIWDL--ASPTPRIKAELTSAAPACYALAISPDSKV 163

Query: 90  LISASSDTTVKVWNAHKGFCMSTLRTHKDYVKALAYAKDKELVASAGLDRQI 141
             S  SD  + VW+ H    +   + H D    +  + D   + + GLD  +
Sbjct: 162 CFSCCSDGNIAVWDLHNEILVRQFQGHTDGASCIDISPDGSRLWTGGLDNTV 7
>01598
          Length = 1545

 Score = 37.4 bits (85), Expect = 0.022,   Method: Compositional matrix adjust.
 Identities = 32/134 (23%), Positives = 58/134 (43%), Gaps = 19/134 (14%)
 Frame = +1

Query: 31  NGVNALQLDPALNRLFTAGRDSIIRIWSVNQHKQDPYIASMEHHTD-----------WVN 79
           NG+   + D     + T  +D  IR+W+++Q KQ  ++  + +              W+ 
Sbjct: 67  NGLTDPERDTGGCLIATGSKDRTIRVWTLSQGKQ-IFMKKLPNQRREAGDTGSRFKVWLA 243

Query: 80  DVVLCCNGKTLISASSDTTVKVWN-------AHKGFCMSTLRTH-KDYVKALAYAKDKEL 131
              L  N + L+S+SS   + +W+       A++ F  S  R H +      A   D + 
Sbjct: 244 IHWLKSNPEQLVSSSSGGDLLLWSLRYTKGQAYQTFQTSDYRPHMRPVFNICASGPDSKT 423

Query: 132 VASAGLDRQIFLWD 145
           + +   DRQ+ LWD
Sbjct: 424 LCTFAQDRQVVLWD 465
>25880
          Length = 423

 Score = 37.0 bits (84), Expect = 0.028,   Method: Composition-based stats.
 Identities = 26/72 (36%), Positives = 39/72 (54%), Gaps = 1/72 (1%)
 Frame = +2

Query: 167 NKDSIYSLAMNQLGTIIVSGSTEKVLRVWD-PRTCAKLMKLKGHTDNVKALLLHRDGTQC 225
           +K  + S+A +     IV+GS EK++RV++  +  A+     GHT  +K  L        
Sbjct: 53  HKHIVKSVAFDNSSENIVTGSNEKLVRVFNLEQPDAEPELYGGHTGAIKRALY------- 211

Query: 226 LSGSSDGTIRLW 237
            SGS DGT+RLW
Sbjct: 212 ASGSEDGTLRLW 247
>01249
          Length = 1743

 Score = 36.2 bits (82), Expect = 0.048,   Method: Compositional matrix adjust.
 Identities = 39/172 (22%), Positives = 69/172 (40%), Gaps = 2/172 (1%)
 Frame = -1

Query: 70   SMEHHTDWVNDVVLCCNGKT--LISASSDTTVKVWNAHKGFCMSTLRTHKDYVKALAYAK 127
            ++  H++ +  + + C G    + S+SSD T K+W+   G  + T+  ++  V  L   K
Sbjct: 1227 TINAHSEPITGLHVGCGGPAARVASSSSDGTCKLWDMLSGALLRTM-VYETGVGCLIMDK 1051

Query: 128  DKELVASAGLDRQIFLWDXXXXXXXXXXXXXXXXXXXXGNKDSIYSLAMNQLGTIIVSGS 187
             +  +  AGLD                            N D + S    Q+        
Sbjct: 1050 QEHFLL-AGLD----------------------------NGDILCSPLFGQI-------- 982

Query: 188  TEKVLRVWDPRTCAKLMKLKGHTDNVKALLLHRDGTQCLSGSSDGTIRLWSL 239
            ++  + V    T A    L+GH+D V  L    DG +  SGS +G + +W++
Sbjct: 981  SQSEVFVSKHTTKAGERVLQGHSDAVTCLAFSSDGQRLASGSQNGKVIIWNM 826
>31384
          Length = 474

 Score = 35.8 bits (81), Expect = 0.057,   Method: Compositional matrix adjust.
 Identities = 28/90 (31%), Positives = 41/90 (45%), Gaps = 3/90 (3%)
 Frame = -1

Query: 24  EVEKYNRNGVNALQLDP-ALNRLF--TAGRDSIIRIWSVNQHKQDPYIASMEHHTDWVND 80
           EV     + V+ L+  P AL   F  +   D+ +  W V Q  Q     + + HT  V D
Sbjct: 294 EVTSPPDDSVSCLKFSPGALPSTFLISGSWDNKVSCWEVQQSGQT-IPKAQQTHTGPVLD 118

Query: 81  VVLCCNGKTLISASSDTTVKVWNAHKGFCM 110
           V    +G  + +AS D T KVW+ +   CM
Sbjct: 117 VDWSDDGTKVFTASCDKTAKVWDLNSNQCM 28

 Score = 33.9 bits (76), Expect = 0.24,   Method: Compositional matrix adjust.
 Identities = 20/77 (25%), Positives = 37/77 (48%), Gaps = 2/77 (2%)
 Frame = -1

Query: 181 TIIVSGSTEKVLRVWDPRTCAKLMK--LKGHTDNVKALLLHRDGTQCLSGSSDGTIRLWS 238
           T ++SGS +  +  W+ +   + +    + HT  V  +    DGT+  + S D T ++W 
Sbjct: 228 TFLISGSWDNKVSCWEVQQSGQTIPKAQQTHTGPVLDVDWSDDGTKVFTASCDKTAKVWD 49

Query: 239 LGQQRCIATYRVHDEGV 255
           L   +C+   + HD  V
Sbjct: 48  LNSNQCMQIAQ-HDAPV 1
>15337
          Length = 860

 Score = 35.8 bits (81), Expect = 0.058,   Method: Compositional matrix adjust.
 Identities = 20/93 (21%), Positives = 42/93 (45%)
 Frame = -1

Query: 33  VNALQLDPALNRLFTAGRDSIIRIWSVNQHKQDPYIASMEHHTDWVNDVVLCCNGKTLIS 92
           ++     P    L   G+D  +R+++ N  +    I +M+ +   +  V    +GK +++
Sbjct: 320 ISEFAFSPCSRYLAVVGQDGHLRVFNYNSME---LIGTMKSYFGGLLCVCWSPDGKYIVT 150

Query: 93  ASSDTTVKVWNAHKGFCMSTLRTHKDYVKALAY 125
              D  V VW+ H+   +     HK +V  +A+
Sbjct: 149 GGEDDLVTVWSFHEKRVVCRGHGHKSWVNVVAF 51
>11915
          Length = 737

 Score = 35.4 bits (80), Expect = 0.075,   Method: Compositional matrix adjust.
 Identities = 18/62 (29%), Positives = 31/62 (50%), Gaps = 1/62 (1%)
 Frame = +1

Query: 182 IIVSGSTEKVLRVWDPRTCAKLMKLKGHTDNVKALLLHRDGTQCL-SGSSDGTIRLWSLG 240
           ++ +G     +++W+  T   L+++  H   V  L    D + CL S S DGT++LW   
Sbjct: 448 VLATGHVSGRIKLWNCETGKLLIEMMDHKATVHDLHFAADNSLCLMSASHDGTVKLWEFD 627

Query: 241 QQ 242
            Q
Sbjct: 628 DQ 633

 Score = 32.7 bits (73), Expect = 0.44,   Method: Compositional matrix adjust.
 Identities = 32/104 (30%), Positives = 49/104 (47%), Gaps = 4/104 (3%)
 Frame = +1

Query: 37  QLDPALNRLFTAGRDSIIRIWSVNQHKQDPYIASMEHHTDWVNDVVLCC-NGKTLISASS 95
           Q D +   L T      I++W+    K    +  M  H   V+D+     N   L+SAS 
Sbjct: 427 QNDSSTLVLATGHVSGRIKLWNCETGK---LLIEMMDHKATVHDLHFAADNSLCLMSASH 597

Query: 96  DTTVKVWNA-HKGFC--MSTLRTHKDYVKALAYAKDKELVASAG 136
           D TVK+W    +G C    TLRT+  +  +  ++ D+  VA+AG
Sbjct: 598 DGTVKLWEFDDQGDCNMYLTLRTNAKHAFSCRWSHDRRYVATAG 729
>12140
          Length = 727

 Score = 35.4 bits (80), Expect = 0.076,   Method: Compositional matrix adjust.
 Identities = 25/112 (22%), Positives = 51/112 (45%), Gaps = 9/112 (8%)
 Frame = +2

Query: 42  LNRLFTAGRDSIIRIWSVNQHKQDPYIA--SMEHHTDWVNDVVLCCN----GKTLISASS 95
           + R  + G D++++IW   +  +  ++    +E H+DWV DV    +       + S S 
Sbjct: 260 VKRFVSGGCDNLVKIW---REDETGWVEDQKLEGHSDWVRDVAWAPSIGLPRNVIASCSQ 430

Query: 96  DTTVKVW---NAHKGFCMSTLRTHKDYVKALAYAKDKELVASAGLDRQIFLW 144
           D  V +W    +   +    L    D V  ++++    ++A +G D ++ LW
Sbjct: 431 DCRVIIWTNDGSSNQWTSRILNKFSDVVWHVSWSVTGNILAVSGGDNKVTLW 586
>14500
          Length = 1238

 Score = 35.4 bits (80), Expect = 0.081,   Method: Compositional matrix adjust.
 Identities = 16/52 (30%), Positives = 28/52 (53%)
 Frame = +3

Query: 186 GSTEKVLRVWDPRTCAKLMKLKGHTDNVKALLLHRDGTQCLSGSSDGTIRLW 237
           G  +  L +W     +++ +L GHT  V  + +  DG   +S ++D T+RLW
Sbjct: 393 GFAQNQLIIWKYPAMSRVAELTGHTARVLHMAMSPDGETVVSAAADETLRLW 548
>16105
          Length = 960

 Score = 35.4 bits (80), Expect = 0.084,   Method: Compositional matrix adjust.
 Identities = 44/185 (23%), Positives = 72/185 (38%), Gaps = 10/185 (5%)
 Frame = -2

Query: 65  DPYIASMEHHTDWVNDVVLCC-NGKTLISASSDTTVKVWNAHKGFCMSTLRT-------- 115
           +P +A    H   V D+  C  N   + SAS D TVKVW       ++ L          
Sbjct: 596 NPLVAG---HKGAVLDIQWCPHNDNVIASASDDCTVKVWQIPDSGLVTNLTDPVVDLVGH 426

Query: 116 HKDYVKALAYAKDKELVASAGLDRQIFLWDXXXXXXXXXXXXXXXXXXXXGNKDSIYSLA 175
            K     + +   + ++ SAG D +I  W+                       D IY ++
Sbjct: 425 QKRCCLIVWHPSAQNVLVSAGADNKILFWNVGTGEPMLEVDV----------PDMIYCMS 276

Query: 176 MNQLGTIIVSGSTEKVLRVWDPRTCAKLMKLKGHTDNVKALLLH-RDGTQCLSGSSDGTI 234
            N  G+ +V    +K LR+ D  + A L + K H     A   + +DG    +G S  + 
Sbjct: 275 FNFNGSRLVCTCKDKKLRIIDSHSGAVLKEGKCHDGAKPAQACYLKDGKVFTTGFSRMSE 96

Query: 235 RLWSL 239
           R +++
Sbjct: 95  RQYAI 81
>14555
          Length = 627

 Score = 35.0 bits (79), Expect = 0.088,   Method: Compositional matrix adjust.
 Identities = 18/57 (31%), Positives = 30/57 (52%)
 Frame = -3

Query: 187 STEKVLRVWDPRTCAKLMKLKGHTDNVKALLLHRDGTQCLSGSSDGTIRLWSLGQQR 243
           + +  + VWD     +   L GH + V  L +  DGT   +GS D T+R+W+  ++R
Sbjct: 409 TNDYTVNVWDALKGMRSTILYGHDNRVSCLRISPDGTSLCTGSWDYTLRIWA*ERER 239
>17298
          Length = 476

 Score = 35.0 bits (79), Expect = 0.090,   Method: Compositional matrix adjust.
 Identities = 20/70 (28%), Positives = 40/70 (57%), Gaps = 2/70 (2%)
 Frame = -1

Query: 170 SIYSLAMNQLGTIIVSGSTEKVLRVWDPRTCAK--LMKLKGHTDNVKALLLHRDGTQCLS 227
           ++  +  N+  T+I+SGS +  +R WD R+ +   +  L   TD+V ++ +     + L+
Sbjct: 206 TVNCVKFNEESTVILSGSLDNTVRAWDTRSRSHTPIQVLDEATDSVTSIQV--SDYEILT 33

Query: 228 GSSDGTIRLW 237
           GS+DG +R +
Sbjct: 32  GSADGRVRRY 3

 Score = 29.6 bits (65), Expect = 3.9,   Method: Compositional matrix adjust.
 Identities = 23/77 (29%), Positives = 37/77 (48%), Gaps = 3/77 (3%)
 Frame = -1

Query: 203 LMKLKGHTDNVKALLLHRDGTQCLSGSSDGTIRLWSLGQQRCIATYRVHDEG---VWALQ 259
           L K + H   V  +  + + T  LSGS D T+R W   + R     +V DE    V ++Q
Sbjct: 233 LRKYRDHAGTVNCVKFNEESTVILSGSLDNTVRAWDT-RSRSHTPIQVLDEATDSVTSIQ 57

Query: 260 VNDAFTHVYSGGRDRKI 276
           V+D    + +G  D ++
Sbjct: 56  VSDY--EILTGSADGRV 12
>26107
          Length = 1338

 Score = 35.0 bits (79), Expect = 0.10,   Method: Compositional matrix adjust.
 Identities = 21/67 (31%), Positives = 32/67 (47%), Gaps = 1/67 (1%)
 Frame = -3

Query: 172  YSLAMNQLGTIIVSGSTEKVLRVWDPRTCAKLMKLKGHTDNVKALL-LHRDGTQCLSGSS 230
            YS   N    +  SG  ++ + +WD  T  K+    GH  +V+++        QC SG+ 
Sbjct: 1069 YSWISNDSQCLTASG--DQTVALWDVETTTKVTTFIGHKCSVRSVASCPSSPAQCASGAR 896

Query: 231  DGTIRLW 237
            DG I LW
Sbjct: 895  DGHIMLW 875
>20662
          Length = 1220

 Score = 33.9 bits (76), Expect = 0.25,   Method: Compositional matrix adjust.
 Identities = 26/94 (27%), Positives = 41/94 (43%), Gaps = 2/94 (2%)
 Frame = +2

Query: 54  IRIWSV-NQHKQDPYIASMEHHTDWVNDVVLCCNGKTLISASSDTTVKVWNAHKGFCMST 112
           + +W + ++ K    ++S   H D    V +  +    +SAS D  +KVWN      + T
Sbjct: 320 VALWELQDEDKMFSMLSSACEHDDMTASVSINSDXSHYLSASYDHGIKVWNTDL-TSLYT 496

Query: 113 LRTHKDYV-KALAYAKDKELVASAGLDRQIFLWD 145
            R H D V     +  +  L  S   D +I LWD
Sbjct: 497 YRAHSDIVWDVQCHPTEPALFLSCSQDGKIVLWD 598

 Score = 33.1 bits (74), Expect = 0.38,   Method: Compositional matrix adjust.
 Identities = 22/75 (29%), Positives = 38/75 (50%), Gaps = 1/75 (1%)
 Frame = +2

Query: 209 HTDNVKALLLHRDGTQCLSGSSDGTIRLWSLGQQRCIATYRVHDEGVWALQVNDAFTHVY 268
           H D   ++ ++ D +  LS S D  I++W+      + TYR H + VW +Q +     ++
Sbjct: 383 HDDMTASVSINSDXSHYLSASYDHGIKVWNT-DLTSLYTYRAHSDIVWDVQCHPTEPALF 559

Query: 269 -SGGRDRKIYCTDLR 282
            S  +D KI   D+R
Sbjct: 560 LSCSQDGKIVLWDVR 604
>34005
          Length = 456

 Score = 33.5 bits (75), Expect = 0.27,   Method: Compositional matrix adjust.
 Identities = 23/107 (21%), Positives = 42/107 (39%), Gaps = 3/107 (2%)
 Frame = +1

Query: 33  VNALQLDPALNRLFTAGRDSIIRIWSVNQHKQDPYIASMEHHTDWVNDVVLCCNGKTLIS 92
           V  L   P    L +   D+ + IW        P + ++  H   V  V  C     +++
Sbjct: 121 VCGLSWSPDATFLASGSNDNSVNIWDSTLGMDVPPLHTLTSHQAAVKAVAWCPWQTRMLA 300

Query: 93  ---ASSDTTVKVWNAHKGFCMSTLRTHKDYVKALAYAKDKELVASAG 136
               ++D  ++ WN + G C+  + T       L   + +ELV+  G
Sbjct: 301 TGGGTNDRHIRFWNTNTGACVKAVDTQSQVCSVLWCKEHRELVSGHG 441
>00825
          Length = 1821

 Score = 32.3 bits (72), Expect = 0.61,   Method: Compositional matrix adjust.
 Identities = 20/66 (30%), Positives = 32/66 (48%), Gaps = 1/66 (1%)
 Frame = -2

Query: 40   PALNRLFTAGRDSIIRIWSVNQ-HKQDPYIASMEHHTDWVNDVVLCCNGKTLISASSDTT 98
            P      +AG D +IRI+ V++ H ++ Y          V  VV   + K + SAS +  
Sbjct: 1199 PTGREFVSAGYDKVIRIFPVDKGHSREVYHTKRMQR---VGSVVWSRDSKYIFSASDEMN 1029

Query: 99   VKVWNA 104
            ++VW A
Sbjct: 1028 IRVWKA 1011

 Score = 29.6 bits (65), Expect = 3.7,   Method: Compositional matrix adjust.
 Identities = 14/50 (28%), Positives = 26/50 (52%)
 Frame = -2

Query: 227  SGSSDGTIRLWSLGQQRCIATYRVHDEGVWALQVNDAFTHVYSGGRDRKI 276
            SG+ DG +  W+L +Q+     + HD  V  +  + +  + +S G D+ I
Sbjct: 1820 SGACDGELICWNLPKQQMACRVQAHDGIVHGMAAHSSGQYFFSCGSDKTI 1671
>30297
          Length = 822

 Score = 32.3 bits (72), Expect = 0.63,   Method: Compositional matrix adjust.
 Identities = 19/78 (24%), Positives = 38/78 (48%), Gaps = 10/78 (12%)
 Frame = -1

Query: 171 IYSLAMNQLGTIIVSGSTEKVLRVWD--------PRTCAK--LMKLKGHTDNVKALLLHR 220
           + ++A N+  T++ S  +   + VWD        P T +   +   +GH ++V  L L  
Sbjct: 375 VSAMATNKANTLLYSADSLGFIYVWDISQYCLETPETDSPDVIQSWRGHVESVSCLDLVE 196

Query: 221 DGTQCLSGSSDGTIRLWS 238
                L+ ++D T+R+W+
Sbjct: 195 QNKVLLTSAADCTVRMWT 142
>04358
          Length = 2430

 Score = 32.3 bits (72), Expect = 0.67,   Method: Compositional matrix adjust.
 Identities = 18/71 (25%), Positives = 36/71 (50%), Gaps = 4/71 (5%)
 Frame = +1

Query: 171  IYSLAMNQLG---TIIVSGSTEKVLRVWDPRTCAKLMKLKGHTDNVKAL-LLHRDGTQCL 226
            +  LA    G   +++ + S+  ++R++     A+   L GH D + ++  LH D    +
Sbjct: 1294 VLGLAAQHTGGADSLVAAASSNFMVRLYSRCRLAQTNTLTGHDDVISSIRFLHTDPGLIM 1473

Query: 227  SGSSDGTIRLW 237
            + S D T+R+W
Sbjct: 1474 TASHDHTVRIW 1506
>04524
          Length = 1340

 Score = 32.0 bits (71), Expect = 0.93,   Method: Compositional matrix adjust.
 Identities = 23/68 (33%), Positives = 31/68 (45%), Gaps = 2/68 (2%)
 Frame = -1

Query: 45  LFTAGRDSIIRIWSV-NQHKQDPYIASMEHHTDWVNDVVLCCNGKTLISASSDTTVKVWN 103
           + T  RD  IR+    N +    Y      HT +VN +V     + LIS S D TV+ WN
Sbjct: 983 VVTCDRDEKIRVSQFPNAYNIHTYCLG---HTQFVNCLVYVEEFRVLISGSGDCTVRAWN 813

Query: 104 AH-KGFCM 110
              K  C+
Sbjct: 812 MEGKQLCL 789

 Score = 30.4 bits (67), Expect = 2.1,   Method: Compositional matrix adjust.
 Identities = 15/39 (38%), Positives = 23/39 (58%), Gaps = 1/39 (2%)
 Frame = -1

Query: 208 GHTDNVKALLLHRDGTQCLSGSSDGTIRLWSL-GQQRCI 245
           GHT  V  L+   +    +SGS D T+R W++ G+Q C+
Sbjct: 905 GHTQFVNCLVYVEEFRVLISGSGDCTVRAWNMEGKQLCL 789
>30295
          Length = 593

 Score = 31.6 bits (70), Expect = 0.99,   Method: Compositional matrix adjust.
 Identities = 25/92 (27%), Positives = 39/92 (42%)
 Frame = +2

Query: 47  TAGRDSIIRIWSVNQHKQDPYIASMEHHTDWVNDVVLCCNGKTLISASSDTTVKVWNAHK 106
           TA  DS+ RI    +     ++A + +   W  D       + L+SAS D  + VW+ + 
Sbjct: 182 TASYDSVGRIQMRTRRTLRXHLAKI-YAMHWATD------SRNLVSASQDGKLIVWDGYT 340

Query: 107 GFCMSTLRTHKDYVKALAYAKDKELVASAGLD 138
              +  +     +V   AYA     VA  GLD
Sbjct: 341 TNKVHAIPLRSSWVMTCAYAPSGGYVACGGLD 436
>06898
          Length = 1979

 Score = 31.6 bits (70), Expect = 1.0,   Method: Compositional matrix adjust.
 Identities = 19/55 (34%), Positives = 31/55 (56%)
 Frame = +1

Query: 293 EKAPVLKMELDRSADPPPAIWVATTKSTVNKWTLKGIHNFRASGDYDNDCTNPIT 347
           EK P   ++ D +AD PP + ++ T  T+ K TLK I N   S ++D +   P++
Sbjct: 874 EKVP---LQQDSNADKPPGMLLSGTSCTIFKDTLKNISN--NSENHDQNTVKPLS 1023
>15118
          Length = 1074

 Score = 31.6 bits (70), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 18/59 (30%), Positives = 28/59 (47%)
 Frame = +3

Query: 192 LRVWDPRTCAKLMKLKGHTDNVKALLLHRDGTQCLSGSSDGTIRLWSLGQQRCIATYRV 250
           + V D  T   +    GH++++  L    DG   ++ S D T+R WSL   R I  + V
Sbjct: 399 VSVIDVDTLRVVRVFSGHSNSITDLSFSGDGRWLITASMDCTVRTWSLVHGRLIDCFAV 575

 Score = 29.6 bits (65), Expect = 4.1,   Method: Compositional matrix adjust.
 Identities = 22/114 (19%), Positives = 45/114 (39%)
 Frame = +3

Query: 31  NGVNALQLDPALNRLFTAGRDSIIRIWSVNQHKQDPYIASMEHHTDWVNDVVLCCNGKTL 90
           +GV  +  D     L TAG D  I+ W      +   +      ++ ++ ++L  +   L
Sbjct: 195 SGVRGVAFDAFNCLLITAGGDCDIKFWRFGSRDRARVLLKELKMSEGISRILLHRDSNML 374

Query: 91  ISASSDTTVKVWNAHKGFCMSTLRTHKDYVKALAYAKDKELVASAGLDRQIFLW 144
                D TV V +      +     H + +  L+++ D   + +A +D  +  W
Sbjct: 375 AVVLEDFTVSVIDVDTLRVVRVFSGHSNSITDLSFSGDGRWLITASMDCTVRTW 536
>13890
          Length = 630

 Score = 31.6 bits (70), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 34/147 (23%), Positives = 63/147 (42%), Gaps = 10/147 (6%)
 Frame = +1

Query: 180 GTIIVSGSTEKVLRVWDPRTCAKLM-KLKGHTDNVKALLLHRDGTQCLSGSSDGTIRLWS 238
           G ++   S+++ +  WD RT   L  ++      V  L+LH   +Q L+ +  G I ++S
Sbjct: 172 GDVVSRESSDRSIMAWDFRTGVILSNQIFQERYTVTRLMLHPYQSQFLAQTQAGYIAVFS 351

Query: 239 ------LGQQRCIATYRVHDEGVWALQVNDAFTHVYSGGRDRKIYCTDLRNP-DIRVLIC 291
                 + + +    ++     + A    D  + VYSG  D K++C        IR L C
Sbjct: 352 TQRPYKMNKNKRFEGHKTAGYNIGASLSQDG-SIVYSGSSDGKLHCYSFNTTKKIRTLHC 528

Query: 292 EEKAPVLKMELDRSADP--PPAIWVAT 316
            +      + +D ++ P  P  +  AT
Sbjct: 529 GQ------VVMDVTSHPLLPSVVAAAT 591
>02960
          Length = 1577

 Score = 31.2 bits (69), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 33/131 (25%), Positives = 58/131 (44%), Gaps = 5/131 (3%)
 Frame = +2

Query: 112  TLRTHKDYVKALAYAKDKELVASAGLDRQIFLWDXXXXXXXXXXXXXXXXXXXXGNKDSI 171
            TL  H + V A+ +  D   V ++  D  + LWD                    G+K ++
Sbjct: 944  TLSGHAEAVSAVRWL-DPHRVVTSSWDHSLRLWDLHTAQQTSLIQ---------GSK-AV 1090

Query: 172  YSLAMNQLGTIIVSGSTEKVLRVWDPRTCAKLMKLK----GHTDNVKALLLHRDGTQC-L 226
              +A + L  ++++GS ++ +R+ DPR C++   +K     HT  V  +          L
Sbjct: 1091 LDVAYSPLSHMLITGSADRHVRLVDPR-CSEGETVKCAFTSHTGWVTGVDWSPTREHLFL 1267

Query: 227  SGSSDGTIRLW 237
            SGS D  ++LW
Sbjct: 1268 SGSYDNVLKLW 1300
>04088
          Length = 511

 Score = 30.8 bits (68), Expect = 1.7,   Method: Compositional matrix adjust.
 Identities = 19/80 (23%), Positives = 37/80 (46%), Gaps = 2/80 (2%)
 Frame = +3

Query: 170 SIYSLAMNQLGTIIVSGSTEKVLRVWDPRTCAKLMKLKGHTDNVKAL--LLHRDGTQCLS 227
           ++ S+   + G   +  S +  +R+ D  T   L +  GH  +   +   L+ + T  +S
Sbjct: 36  AVTSVTFTRDGQCSLVSSQDNTVRLMDKDTGEMLNEFTGHKHSQYKIDSCLNNEDTLVVS 215

Query: 228 GSSDGTIRLWSLGQQRCIAT 247
           GS DG +  W L + + + T
Sbjct: 216 GSEDGKVYFWDLVEAKLVDT 275
>25930
          Length = 419

 Score = 30.8 bits (68), Expect = 1.7,   Method: Compositional matrix adjust.
 Identities = 17/62 (27%), Positives = 30/62 (48%), Gaps = 4/62 (6%)
 Frame = +1

Query: 182 IIVSGSTEKVLRVWD----PRTCAKLMKLKGHTDNVKALLLHRDGTQCLSGSSDGTIRLW 237
            +  GS    + ++D    P   A++    G  D++K L    D T+ +S S  GT+++W
Sbjct: 100 FVAVGSVRGDILIYDVRLEPWRLARIAPSNGQDDSIKNLNWSLDATRLISVSESGTLQVW 279

Query: 238 SL 239
            L
Sbjct: 280 DL 285
>27681
          Length = 465

 Score = 30.8 bits (68), Expect = 2.0,   Method: Compositional matrix adjust.
 Identities = 23/81 (28%), Positives = 38/81 (46%), Gaps = 14/81 (17%)
 Frame = +2

Query: 171 IYSLAMNQLGTIIVSGSTEKVLRVWD-----PRTCAKLMKL----KGHTD-----NVKAL 216
           ++  A N    ++ SGS +   R+W+     P    +L+      KG T+     +V +L
Sbjct: 2   VFICAWNPTNDLLASGSGDSTARIWNMTSETPNNANQLVLRHCIQKGGTEVPSNKDVTSL 181

Query: 217 LLHRDGTQCLSGSSDGTIRLW 237
             + +GT   +GS DG  RLW
Sbjct: 182 DWNSEGTLLATGSYDGYARLW 244
>07151
          Length = 512

 Score = 30.4 bits (67), Expect = 2.2,   Method: Compositional matrix adjust.
 Identities = 11/26 (42%), Positives = 18/26 (69%)
 Frame = -1

Query: 120 VKALAYAKDKELVASAGLDRQIFLWD 145
           VK   ++KDK ++ + G+DR I LW+
Sbjct: 155 VKCFDFSKDKNIIVTGGMDRIIRLWN 78
>33180
          Length = 460

 Score = 29.6 bits (65), Expect = 4.0,   Method: Compositional matrix adjust.
 Identities = 17/66 (25%), Positives = 33/66 (50%), Gaps = 1/66 (1%)
 Frame = -2

Query: 209 HTDNVKALLLHRDGTQCLSGSSDGTIRLWSLGQQRCIATYRVHDEGVWALQVNDAFTHV- 267
           H+  + +L+   D T+ + G++DG + ++     +       HD+ V A+   D  + + 
Sbjct: 456 HSFCIFSLMFSSDNTEIVGGANDGCLYVYDRESNQRTLKIDAHDDDVNAVAFADDSSQIL 277

Query: 268 YSGGRD 273
           YSGG D
Sbjct: 276 YSGGDD 259
>38039
          Length = 816

 Score = 29.6 bits (65), Expect = 4.5,   Method: Compositional matrix adjust.
 Identities = 14/44 (31%), Positives = 21/44 (47%)
 Frame = -1

Query: 60  NQHKQDPYIASMEHHTDWVNDVVLCCNGKTLISASSDTTVKVWN 103
           N+H   P     + H D +  +  C   K   S+S D T++VWN
Sbjct: 540 NRHDHKPD----DDHVDLITGLTSCSRMKLFASSSMDGTIRVWN 421
>07665
          Length = 435

 Score = 29.3 bits (64), Expect = 4.8,   Method: Compositional matrix adjust.
 Identities = 23/105 (21%), Positives = 40/105 (38%)
 Frame = -2

Query: 102 WNAHKGFCMSTLRTHKDYVKALAYAKDKELVASAGLDRQIFLWDXXXXXXXXXXXXXXXX 161
           W+ + G  + TL  H D + AL ++ ++  +  A     I +WD                
Sbjct: 392 WDLNDGKNLYTLE-HNDIINALCFSPNRYWLCVA-YGPSIKIWDLACKKTVEELRPEVVS 219

Query: 162 XXXXGNKDSIYSLAMNQLGTIIVSGSTEKVLRVWDPRTCAKLMKL 206
                 +    SLA +  G  + +G ++  +RVW     A  M L
Sbjct: 218 PTSKAEQPQCLSLAWSTDGQTLFAGYSDNTIRVWQVSVSAH*MDL 84
>16199
          Length = 694

 Score = 29.3 bits (64), Expect = 5.7,   Method: Compositional matrix adjust.
 Identities = 10/37 (27%), Positives = 21/37 (56%)
 Frame = +2

Query: 180 GTIIVSGSTEKVLRVWDPRTCAKLMKLKGHTDNVKAL 216
           G I  +G+ + V+++WD +  A +   +GH   V ++
Sbjct: 107 GLIFATGTEDSVIKIWDLKERANVANFQGHQGPVTSI 217
>03734
          Length = 1963

 Score = 28.5 bits (62), Expect = 8.2,   Method: Compositional matrix adjust.
 Identities = 24/85 (28%), Positives = 36/85 (42%), Gaps = 1/85 (1%)
 Frame = -2

Query: 54   IRIWSVNQ-HKQDPYIASMEHHTDWVNDVVLCCNGKTLISASSDTTVKVWNAHKGFCMST 112
            +RIWSV   H     I   E  T W   V+      T++S  S   V  WN  +G  ++ 
Sbjct: 1953 LRIWSVKSGHALQRIIIGGEDTTVWCLAVL---GDLTIVSGDSRGKVCFWNGKQGTRIAH 1783

Query: 113  LRTHKDYVKALAYAKDKELVASAGL 137
             ++HK  V  L   + +  V   G+
Sbjct: 1782 FQSHKADVLTLCADESETNVFCGGV 1708
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6681219|ref|NP_033494.1| dihydropyrimidinase-like 3
isoform 2 [Mus musculus]
         (570 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

14768                                                                 207   2e-68
34622                                                                 151   9e-37
29305                                                                  39   0.004
03868                                                                  30   3.6  
06829                                                                  28   7.6  
14916                                                                  28   7.9  
>14768
          Length = 697

 Score =  207 bits (526), Expect(2) = 2e-68,   Method: Compositional matrix adjust.
 Identities = 92/167 (55%), Positives = 128/167 (76%)
 Frame = -1

Query: 316 YINSLLASGDLQLSGSAHCTFSTAQKAIGKDNFTAIPEGTNGVEERMSVIWDKAVATGKM 375
           Y+  LLA+ DLQ++G+ +CTF   QKA+GKD+F +IP G NGVE+RMSVIW+K V +GKM
Sbjct: 505 YLMDLLANNDLQVTGTDNCTFRADQKALGKDDFRSIPNGVNGVEDRMSVIWEKGVQSGKM 326

Query: 376 DENQFVAVTSTNAAKIFNLYPRKGRIAVGSDSDLVIWDPDALKIVSAKNHQSVAEYNIFE 435
           D  +FVAVTS+ AAKIFN+YPRKGRIAVGSD+D+V+WD +  + +SA+ H    ++NIFE
Sbjct: 325 DACRFVAVTSSAAAKIFNIYPRKGRIAVGSDADVVVWDGNQTRTISAETHHQAVDFNIFE 146

Query: 436 GMELRGAPLVVICQGKIMLEDGNLHVTQGAGRFIPCSPFSDYVYKRI 482
           G++  G P+ VI  G +++++G + VT+G+GRFIP   F + VY RI
Sbjct: 145 GLQCHGVPVYVIXNGNVVVDNGEVKVTKGSGRFIPSPCFPEAVYGRI 5

 Score = 70.9 bits (172), Expect(2) = 2e-68,   Method: Compositional matrix adjust.
 Identities = 32/51 (62%), Positives = 39/51 (76%)
 Frame = -2

Query: 252 VTKVMSKSAADLISQARKKGNVVFGEPITASLGIDGTHYWSKNWAKAAAFV 302
           V  +MSKS+AD+IS +R+KG VVFGEPI ASLG DGTH W++ W  AA  V
Sbjct: 696 VVHIMSKSSADVISASRRKGKVVFGEPIAASLGTDGTHQWNRCWRHAAGHV 544
>34622
          Length = 477

 Score =  151 bits (381), Expect = 9e-37,   Method: Compositional matrix adjust.
 Identities = 67/128 (52%), Positives = 96/128 (75%), Gaps = 2/128 (1%)
 Frame = -3

Query: 360 ERMSVIWDKAVATGKMDENQFVAVTSTNAAKIFNLYPRKGRIAVGSDSDLVIWDPDALKI 419
           +RMSVIW+K V  GKMD  +FVA TS NAA+I+N+YPRKGRIAVGSD+D+V+WD +  + 
Sbjct: 475 DRMSVIWEKGVMMGKMDACRFVAATSANAARIYNIYPRKGRIAVGSDADVVVWDGNQTRT 296

Query: 420 VSAKNHQSVAEYNIFEGMELRGAPLVVICQGKIMLEDGNLHVTQGAGRFI--PCSPFSDY 477
           +SA+ H    ++NIFEG++  G P+ V+  G+++++DG L VTQG GR +  PC+  ++ 
Sbjct: 295 ISAETHHQAVDFNIFEGLQCHGVPVYVVSNGQVVVDDGQLKVTQGLGRLVSTPCN--AET 122

Query: 478 VYKRIKAR 485
           VY R+KAR
Sbjct: 121 VYGRVKAR 98
>29305
          Length = 881

 Score = 39.3 bits (90), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 20/32 (62%), Positives = 24/32 (75%), Gaps = 3/32 (9%)
 Frame = -3

Query: 86  VDDFFQGTKAALAGGTTMIIDH---VVPEPES 114
            DDF+ GTKAALAGGTTMI+D    VV  P++
Sbjct: 879 CDDFYIGTKAALAGGTTMIMDFVFVVVLHPDN 784
>03868
          Length = 1865

 Score = 29.6 bits (65), Expect = 3.6,   Method: Compositional matrix adjust.
 Identities = 17/34 (50%), Positives = 19/34 (55%), Gaps = 4/34 (11%)
 Frame = -2

Query: 237 FRAIT----VASQTNCPLYVTKVMSKSAADLISQ 266
           FR  T    V  QTNCPL VT   S SA D+ S+
Sbjct: 805 FRRFTSRDDVVDQTNCPLNVTDDGSCSAGDVDSE 704
>06829
          Length = 880

 Score = 28.5 bits (62), Expect = 7.6,   Method: Compositional matrix adjust.
 Identities = 21/76 (27%), Positives = 35/76 (46%), Gaps = 1/76 (1%)
 Frame = -1

Query: 405 SDSDLVIWDPDALKIVSAKNHQSVAEYNIFEGMELRGAPLVVIC-QGKIMLEDGNLHVTQ 463
           ++ D V W  DA + +S    +S   ++  E      +P   +C  G   L +  LH+ Q
Sbjct: 229 TELDAVFWIQDAWQTISLDTIKS--SFHKAEFPHASPSPPASLCPSGLEPLPNNFLHLVQ 56

Query: 464 GAGRFIPCSPFSDYVY 479
            AGR    +P S ++Y
Sbjct: 55  EAGRVFRFTPMSAHLY 8
>14916
          Length = 883

 Score = 28.5 bits (62), Expect = 7.9,   Method: Compositional matrix adjust.
 Identities = 21/76 (27%), Positives = 35/76 (46%), Gaps = 1/76 (1%)
 Frame = +1

Query: 405 SDSDLVIWDPDALKIVSAKNHQSVAEYNIFEGMELRGAPLVVIC-QGKIMLEDGNLHVTQ 463
           ++ D V W  DA + +S    +S   ++  E      +P   +C  G   L +  LH+ Q
Sbjct: 148 TELDAVFWIQDAWQTISLDTIKS--SFHKAEFPHASPSPPASLCPSGLEPLPNNFLHLVQ 321

Query: 464 GAGRFIPCSPFSDYVY 479
            AGR    +P S ++Y
Sbjct: 322 EAGRVFRFTPMSAHLY 369
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|82882528|ref|XP_889298.1| PREDICTED: CLASP1 isoform 1
[Mus musculus]
         (1536 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

25317                                                                 251   4e-68
13482                                                                 169   7e-42
27718                                                                 104   7e-30
27421                                                                  54   6e-07
21443                                                                  35   0.21 
20120                                                                  35   0.23 
00036                                                                  31   4.6  
>25317
          Length = 1017

 Score =  251 bits (642), Expect(2) = 4e-68,   Method: Compositional matrix adjust.
 Identities = 114/229 (49%), Positives = 165/229 (72%)
 Frame = +2

Query: 309 VPVVQIYSSRDLEESINKIREILSDDKHDWEQRVNALKKIRSLLLAGAAEYDNFFQHLRL 368
           + ++Q++SSRD+ + ++K+   LSD   DWE+RV+  K  R+L++ GA ++D F Q LR 
Sbjct: 56  IALLQLFSSRDMMDQMSKVNAALSDANLDWEKRVDNFKIFRALVMNGATDHDEFHQQLRG 235

Query: 369 LDGAFKLSAKDLRSQVVREACITLGHLSSVLGNKFDHGAEAIMPTIFNLIPNSAKIMATS 428
           ++ AF    KDLRSQVVREAC+T+ +++  LG+K D  AE + P +FNLIPNSAKIMATS
Sbjct: 236 MEPAFVSGVKDLRSQVVREACVTIAYMAQQLGSKLDRFAEVVFPALFNLIPNSAKIMATS 415

Query: 429 GVVAVRLIIRHTHIPRLIPVITSNCTSKSVAVRRRCFEFLDLLLQEWQTHSLERHISVLA 488
           G V +R II++ H  RLIP++T N ++KS  +RR+  EFL+ LL  W TH+LE+HI++L 
Sbjct: 416 GCVCIRFIIQYVHTNRLIPILTGNMSTKSNVIRRQSCEFLNQLLHSWGTHTLEKHIALLQ 595

Query: 489 ETIKKGIHDADSEARIEARKCYWGFHSHFSREAEHLYHTLESSYQKALQ 537
           ++I++GI DADSEAR  +RK +WGF  HF  +A+ L  +L+ S QK LQ
Sbjct: 596 DSIRRGISDADSEARAFSRKAFWGFAEHFKSQADALLASLDPSKQKLLQ 742

 Score = 26.6 bits (57), Expect(2) = 4e-68,   Method: Composition-based stats.
 Identities = 11/16 (68%), Positives = 14/16 (87%)
 Frame = +1

Query: 298 DEEDFIKAFDDVPVVQ 313
           DEE FIK+F+DVP V+
Sbjct: 7   DEELFIKSFEDVPKVK 54
>13482
          Length = 530

 Score =  169 bits (428), Expect = 7e-42,   Method: Compositional matrix adjust.
 Identities = 78/150 (52%), Positives = 108/150 (72%)
 Frame = +2

Query: 298 DEEDFIKAFDDVPVVQIYSSRDLEESINKIREILSDDKHDWEQRVNALKKIRSLLLAGAA 357
           DEE FIK+F+DVP V+++SSRD+ + ++K+   LSD   DWE+RV+  K  R+L++ GA 
Sbjct: 80  DEELFIKSFEDVPKVKLFSSRDMMDQMSKVNAALSDANLDWEKRVDNFKIFRALVMNGAT 259

Query: 358 EYDNFFQHLRLLDGAFKLSAKDLRSQVVREACITLGHLSSVLGNKFDHGAEAIMPTIFNL 417
           ++D F Q LR ++ AF    KDLRSQVVREAC+T+ +++  LG+K D  AE + P +FNL
Sbjct: 260 DHDEFHQQLRGMEPAFVSGVKDLRSQVVREACVTIAYMAQQLGSKLDRFAEVVFPALFNL 439

Query: 418 IPNSAKIMATSGVVAVRLIIRHTHIPRLIP 447
           IPNSAKIMATSG V +R II++ H  R  P
Sbjct: 440 IPNSAKIMATSGCVCIRFIIQYVHTNRQTP 529
>27718
          Length = 388

 Score =  104 bits (260), Expect(2) = 7e-30,   Method: Compositional matrix adjust.
 Identities = 50/88 (56%), Positives = 64/88 (72%)
 Frame = -3

Query: 111 DQTLLLKIMDQAANPQYVWDRMLGGFKHKNFRTREGICLCLIATLNASGAQTLTLSKIVP 170
            Q LLLK+M  A++PQYV++RM G F HK +  REG+ +CL  T+N  GA++L LSK VP
Sbjct: 266 SQQLLLKLMMPASSPQYVFERMSGAFSHKLWHVREGMLVCLQNTINRYGARSLQLSKTVP 87

Query: 171 HICNLLGDPNSQVRDAAINSLVEIYRHV 198
            IC LL D N QVR+AA+ +L EIYRHV
Sbjct: 86  AICKLLEDQNLQVREAAVVTLTEIYRHV 3

 Score = 45.8 bits (107), Expect(2) = 7e-30,   Method: Compositional matrix adjust.
 Identities = 21/28 (75%), Positives = 23/28 (82%)
 Frame = -1

Query: 83  DRFKAQIGTVLPSLIDRLGDAKDSVREQ 110
           + FK  I TVLPS+IDRLGDAKD VREQ
Sbjct: 349 EEFKPHISTVLPSVIDRLGDAKDQVREQ 266
>27421
          Length = 374

 Score = 53.5 bits (127), Expect = 6e-07,   Method: Compositional matrix adjust.
 Identities = 39/129 (30%), Positives = 54/129 (41%)
 Frame = -3

Query: 708 VTPSSEKRSKIPRSQGCSRETSPNRIGLARSSRIPRPSMSQGCXXXXXXXXXXXXXPARG 767
           +TP  ++++ IPRSQG SRE SPNR    R  R+                          
Sbjct: 276 MTPKGKRKTGIPRSQGASREASPNRRTYGRERRL-------------------------- 175

Query: 768 FTPLDRFGLGQSGRIPGSVNAMRVLSTSTDLEAAVADALKKPVRRRYEPYGMYXXXXXXX 827
                    G  G   G + + RVL   +D+E A+ DAL +P R+RY+   +Y       
Sbjct: 174 --------SGSKGSHTGPLISQRVLRPGSDVEDALHDALSRPNRKRYD---VYDSDDAAS 28

Query: 828 XXXXVCSER 836
               VCSER
Sbjct: 27  ETSSVCSER 1
>21443
          Length = 610

 Score = 35.0 bits (79), Expect = 0.21,   Method: Compositional matrix adjust.
 Identities = 19/59 (32%), Positives = 31/59 (52%)
 Frame = -1

Query: 138 HKNFRTREGICLCLIATLNASGAQTLTLSKIVPHICNLLGDPNSQVRDAAINSLVEIYR 196
           H N  +   ICL +   L +  +  LT+SK++  IC++L DPN    D  +  +  IY+
Sbjct: 313 HPNINSNGSICLDI---LRSQWSPALTISKVLLSICSMLTDPNPD--DPLVPEIARIYK 152
>20120
          Length = 1816

 Score = 35.0 bits (79), Expect = 0.23,   Method: Compositional matrix adjust.
 Identities = 33/117 (28%), Positives = 47/117 (40%), Gaps = 20/117 (17%)
 Frame = +3

Query: 108 REQDQTLLLKIMDQAANPQYVWDRMLGGFKHKNFRTREGICLC----------------- 150
           R  DQ+ L  +   A     V D+ L   + K +R  E ICLC                 
Sbjct: 549 RYTDQSHLRTLYTLAEQHVQVSDKAL---QKKAYRILEEICLCESEACREFLMSNLTEIQ 719

Query: 151 --LIATLNASGAQTLTLS-KIVPHICNLLGDPNSQVRDAAINSLVEIYRHVGERVRA 204
             L+ +L+AS   T     + +  IC  L  PN+    A +   +   R VGE+VRA
Sbjct: 720 QLLLGSLSASAPNTRNPRLRCLTCICQQLTQPNTAFIQAVVPEAIMCTRGVGEKVRA 890
>00036
          Length = 1324

 Score = 30.8 bits (68), Expect = 4.6,   Method: Composition-based stats.
 Identities = 14/29 (48%), Positives = 18/29 (62%)
 Frame = +3

Query: 64   YKVVLLGMDILSALVTRLQDRFKAQIGTV 92
            YK V+  +DI    +TRL D FK  +GTV
Sbjct: 1185 YKQVMFHLDIFHCGITRLTDYFKFPMGTV 1271
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|134949013|ref|NP_033098.2| Rho-associated coiled-coil
forming kinase 2 [Mus musculus]
         (1388 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

03240                                                                 256   5e-68
30755                                                                 129   1e-29
18484                                                                 113   1e-25
29793                                                                 110   4e-24
31885                                                                 110   5e-24
27405                                                                 103   4e-22
12721                                                                 100   5e-21
18921                                                                  97   6e-20
00300                                                                  96   8e-20
14420                                                                  88   2e-17
01392                                                                  87   6e-17
01707                                                                  86   8e-17
26560                                                                  84   4e-16
15910                                                                  83   8e-16
13592                                                                  80   4e-15
09606                                                                  80   5e-15
13066                                                                  79   1e-14
26156                                                                  64   3e-14
12786                                                                  76   7e-14
13212                                                                  76   1e-13
01718                                                                  75   2e-13
17975                                                                  75   2e-13
19094                                                                  70   5e-12
26711                                                                  69   2e-11
01060                                                                  69   2e-11
01756                                                                  68   3e-11
14126                                                                  67   5e-11
00486                                                                  67   6e-11
06405                                                                  67   7e-11
05015                                                                  49   9e-11
16708                                                                  65   1e-10
17932                                                                  65   2e-10
18663                                                                  63   7e-10
21079                                                                  62   2e-09
04591                                                                  61   3e-09
25019                                                                  60   5e-09
21433                                                                  58   2e-08
19761                                                                  56   1e-07
03508                                                                  55   1e-07
14748                                                                  55   2e-07
01966                                                                  48   2e-07
27546                                                                  55   2e-07
29581                                                                  55   3e-07
11185                                                                  52   1e-06
00392                                                                  51   3e-06
00715                                                                  51   4e-06
17722                                                                  51   4e-06
28157                                                                  50   5e-06
19301                                                                  48   2e-05
07833                                                                  48   3e-05
04852                                                                  48   3e-05
37602                                                                  47   5e-05
38560                                                                  47   6e-05
37063                                                                  47   7e-05
28638                                                                  47   7e-05
11780                                                                  45   2e-04
14116                                                                  45   2e-04
04138                                                                  45   3e-04
21808                                                                  44   4e-04
00638                                                                  43   7e-04
32359                                                                  33   7e-04
07940                                                                  43   0.001
12672                                                                  42   0.002
18996                                                                  41   0.003
02638                                                                  41   0.003
32957                                                                  40   0.005
06358                                                                  40   0.005
18401                                                                  40   0.005
29590                                                                  40   0.005
20152                                                                  39   0.012
13840                                                                  39   0.016
07291                                                                  38   0.024
18481                                                                  38   0.035
17300                                                                  37   0.046
33586                                                                  37   0.053
29360                                                                  37   0.055
11404                                                                  37   0.056
26009                                                                  37   0.070
31489                                                                  36   0.10 
01106                                                                  36   0.11 
21210                                                                  35   0.17 
17516                                                                  33   1.1  
35187                                                                  32   2.0  
25445                                                                  31   3.1  
27274                                                                  31   3.3  
21800                                                                  30   4.7  
>03240
          Length = 1683

 Score =  256 bits (653), Expect = 5e-68,   Method: Compositional matrix adjust.
 Identities = 134/328 (40%), Positives = 188/328 (57%), Gaps = 44/328 (13%)
 Frame = -3

Query: 92   YDVVKVIGRGAFGEVQLVRHKASQKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANSPW 151
            ++ +K +G GAFGEV L R   +  +YAMK L K +++KR+  A    ERDI+A A++ W
Sbjct: 1285 FEKIKTLGVGAFGEVSLCRKNDTGMLYAMKTLRKSDVLKRNQVAHVKAERDILAEADNEW 1106

Query: 152  VVQLFCAFQDDRYLYMVMEYMPGGDLVNLMSNYDV-PEKWAKFYTAEVVLALDAIHSMGL 210
            VV+L+ +FQD  YLY VM+Y+PGGDL+ L+   ++  E  A+FY AE+V A++++H MG 
Sbjct: 1105 VVKLYYSFQDHNYLYFVMDYVPGGDLMGLLIRMEILDEPLARFYVAELVQAIESVHRMGF 926

Query: 211  IHRDVKPDNMLLDKHGHLKLADFGTCMKMDETGM-----------------VHC------ 247
            IHRD+KPDN+L+D++GH+KL DFG C     T                   V C      
Sbjct: 925  IHRDIKPDNILIDRNGHIKLTDFGLCTGFRWTHNSKYYQRDGTHARQDSMEVKCQLDEQC 746

Query: 248  --------------------DTAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLFEM 287
                                 + VGTP+YI+PEVL   GG   Y   CDWWSVGV LFEM
Sbjct: 745  QCEILKPLERRRKREQRCLAHSLVGTPNYIAPEVLSRLGG---YTSVCDWWSVGVILFEM 575

Query: 288  LVGDTPFYADSLVGTYSKIMDHKNSLCFPEDTEISKHAKNLICAFLTDREVRLGRNGVEE 347
            LVG  PFYA++   T  K+++ K+ L  P ++ +S+ AK+LI       + RLG NG  E
Sbjct: 574  LVGHPPFYANTPAETQYKVINWKDMLKIPRESNLSQPAKDLILRLCCGSDDRLGLNGAGE 395

Query: 348  IKQHPFFKNDQWNWDNIRETAAPVVPEL 375
            IK H FF     N++ +R+   P VP +
Sbjct: 394  IKTHMFFAG--VNFETLRKQQPPYVPNI 317
>30755
          Length = 1137

 Score =  129 bits (323), Expect = 1e-29,   Method: Composition-based stats.
 Identities = 76/191 (39%), Positives = 111/191 (58%), Gaps = 3/191 (1%)
 Frame = +2

Query: 188 EKWAKFYTAEVVLALDAIHSMGLIHRDVKPDNMLLDKHGHLKLADFGTCMKMDETGMVHC 247
           E+  +FY AE++ AL  +HS G+I+RD+K +N+LLDK GH+K+ADFG C K D T     
Sbjct: 29  EERTRFYGAEIISALGYLHSQGIIYRDLKLENLLLDKDGHIKVADFGLC-KEDITYGRTT 205

Query: 248 DTAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLFEMLVGDTPFYADSLVGTYSKIM 307
            T  GTP+Y++PEVL     D  YGR  DWW  GV ++EM+ G  PFY       ++ I+
Sbjct: 206 KTFCGTPEYLAPEVLD----DNDYGRAVDWWGTGVVMYEMICGRLPFYNRDHDVLFTLIL 373

Query: 308 DHKNSLCFPEDTEISKHAKNLICAFLT-DREVRL--GRNGVEEIKQHPFFKNDQWNWDNI 364
                + FP +  I+  AK+L+   L  D   RL  G++ V+EI+ HPFF +  W     
Sbjct: 374 --VEDVKFPRN--ITDEAKSLLSGLLAKDPRNRLGGGQDDVKEIQAHPFFASINWTDLVQ 541

Query: 365 RETAAPVVPEL 375
           ++   P  P++
Sbjct: 542 KKITPPFKPQV 574
>18484
          Length = 635

 Score =  113 bits (283), Expect(2) = 1e-25,   Method: Composition-based stats.
 Identities = 65/155 (41%), Positives = 87/155 (56%), Gaps = 1/155 (0%)
 Frame = +1

Query: 188 EKWAKFYTAEVVLALDAIHSMGLIHRDVKPDNMLLDKHGHLKLADFGTCMKMDETGMVHC 247
           E  A FY AE+ + L  +H  G+I+RD+K DN++LD  GH+K+ADFG C K   TG    
Sbjct: 40  EPVAAFYAAEIAVGLFFLHDQGIIYRDLKLDNVMLDSEGHIKIADFGMC-KEGMTGDATT 216

Query: 248 DTAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLFEMLVGDTPFYADSLVGTYSKIM 307
            T  GTPDYI+PE++  Q     Y +  DWW+ GV LFEML G  PF  +     +S I 
Sbjct: 217 RTFCGTPDYIAPEIVLYQP----YSKSVDWWAYGVLLFEMLAGQPPFDGEDEDELFSSIT 384

Query: 308 DHKNSLCFPEDTEISKHAKNLICAFLTDREV-RLG 341
           DH  S  +P+   +S+ A +L    L      RLG
Sbjct: 385 DHNVS--YPK--AMSREAVSLCKGLLMKNPTKRLG 477

 Score = 23.1 bits (48), Expect(2) = 1e-25,   Method: Compositional matrix adjust.
 Identities = 10/33 (30%), Positives = 16/33 (48%)
 Frame = +2

Query: 343 NGVEEIKQHPFFKNDQWNWDNIRETAAPVVPEL 375
           NG  +I+ H FF+   W+     E   P  P++
Sbjct: 488 NGERDIRDHAFFRRIVWDKIKSMEVQPPYKPKI 586
>29793
          Length = 1088

 Score =  110 bits (275), Expect = 4e-24,   Method: Compositional matrix adjust.
 Identities = 101/321 (31%), Positives = 154/321 (47%), Gaps = 18/321 (5%)
 Frame = +2

Query: 744  RSLKQKVENLLLEAEKRCSILDCDLKQSQQKLNELLKQKDVLNEDVRNLTLKIEQET--- 800
            +S++ KVE  LLE EK+ S +  DL Q QQ+              V   +   +Q +   
Sbjct: 149  KSMRHKVEARLLETEKKBSEMGVDLMQLQQR--------------VERCSPSYKQRSTRA 286

Query: 801  -------QKRC-----LMQNDLKMQTQQVNTLKMSEKQIKQENNHLMEMKMNLEKQNTEL 848
                    ++C     LMQ D+K  +  +N  K  EKQ+ +E + L   K   +++   L
Sbjct: 287  GGCPCKWSRKCKTYDNLMQGDIKTTSMDLNKAKSKEKQLAKEISDLKHEKKTADQEIRRL 466

Query: 849  RKERQDADGQMKELQDQLEAEQYFSTLYKTQVRXXXXXXXXXXXXXXXXXXXXXXXXXXX 908
            + E   ++ QM+E Q+QLEAE YFS+LYKTQV+                           
Sbjct: 467  KDEISVSELQMRETQEQLEAENYFSSLYKTQVKELKEEVDEKQKQIQDLTSDVQNILHEK 646

Query: 909  XSLAAQLEITLTKADSEQLARSIAEEQYSDXXXXXXXXXXXXXXXXARHKQELTEKDTTI 968
             S+  Q+++  TKADSE LAR IAEEQ SD                +RHK E+ +K++ +
Sbjct: 647  ESILTQVQLLHTKADSEALARGIAEEQLSDVEKEKTMLELEIKELMSRHKNEMNKKESQL 826

Query: 969  ASLEETNRTLTSDVXXXXXXXXXXXXXXXDSQEQLSKLKDEEMSAAAIKAQFE---KQLL 1025
            A+LE+  R  + +                D   ++ +L  E++ ++   ++F+   KQL 
Sbjct: 827  AALEDQKRDYSINT-------EKLQQDKDDLNNKIKRLA-EDLQSSKNMSEFDKLKKQLE 982

Query: 1026 NERTLKTQAVNKLAEIMNRKE 1046
            +E+  K QAVNKLAEIMNRKE
Sbjct: 983  DEKLKKIQAVNKLAEIMNRKE 1045
>31885
          Length = 529

 Score =  110 bits (274), Expect = 5e-24,   Method: Composition-based stats.
 Identities = 59/162 (36%), Positives = 92/162 (56%), Gaps = 5/162 (3%)
 Frame = -2

Query: 142 DIMAFANSPWVVQLFCAFQDDRYLYMVMEYMPGGDL-VNLMSNYDVPEKWAKFYTAEVVL 200
           D++   + P++V L+ AFQD+  L+MV++   GGDL  ++       E   KFY  ++ L
Sbjct: 516 DMLTRLDHPFLVNLWYAFQDEEDLFMVVDLFLGGDLRYHMQQEVSFREDCVKFYLCQLAL 337

Query: 201 ALDAIHSMGLIHRDVKPDNMLLDKHGHLKLADFGTCMKMDETGMVHCDTAVGTPDYISPE 260
            LD + S  ++HRD+KPDN+LLD+ GH  + DF    ++++  +    +  GT  Y++PE
Sbjct: 336 VLDYLRSQKIVHRDIKPDNILLDEQGHCHVTDFNIATQLEDDELA--TSTSGTRPYMAPE 163

Query: 261 V----LKSQGGDGYYGRECDWWSVGVFLFEMLVGDTPFYADS 298
           V    +  + G   YG   DWWS+GV LFE+L    PF   S
Sbjct: 162 VYGVAINERRG---YGFPVDWWSLGVSLFELLKKRRPFSVHS 46
>27405
          Length = 532

 Score =  103 bits (258), Expect = 4e-22,   Method: Composition-based stats.
 Identities = 64/183 (34%), Positives = 100/183 (54%), Gaps = 6/183 (3%)
 Frame = -3

Query: 102 AFGEVQLVRHKASQKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFAN----SPWVVQLFC 157
            FGEV   R   + K+YAMK L K  +  +        ER +++  +    SP++V +  
Sbjct: 530 GFGEVYGCRKADTGKMYAMKCLDKKRIKMKGGETLALNERIMLSLVSTGEGSPFIVCMTY 351

Query: 158 AFQDDRYLYMVMEYMPGGDLVNLMSNYDV-PEKWAKFYTAEVVLALDAIHSMGLIHRDVK 216
           AFQ    L  +++ M GGDL   +S + V  EK  +FY AEV+L L+ +HS  +++RD+K
Sbjct: 350 AFQTPEKLCFILDLMNGGDLHYHLSQHGVFTEKEVRFYAAEVMLGLEHMHSRFVVYRDLK 171

Query: 217 PDNMLLDKHGHLKLADFGTCMKMDETGMVHCDTAVGTPDYISPEVL-KSQGGDGYYGREC 275
           P N+LLD++GH++++D G      +        +VGT  Y++PEVL K Q     Y    
Sbjct: 170 PANILLDENGHVRISDLGLACDFSKK---KPHASVGTHGYMAPEVLMKGQA----YDSSA 12

Query: 276 DWW 278
           DW+
Sbjct: 11  DWF 3
>12721
          Length = 821

 Score =  100 bits (248), Expect = 5e-21,   Method: Compositional matrix adjust.
 Identities = 60/211 (28%), Positives = 114/211 (54%)
 Frame = +1

Query: 98  IGRGAFGEVQLVRHKASQKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANSPWVVQLFC 157
           IG G+ G V +   +  +++     + K ++ K+      + E  +M   + P +V+++ 
Sbjct: 112 IGEGSTGIVCIATSRDGRQMA----VKKMDLRKQQRRELLFNEVVVMRDYHHPNIVEMYN 279

Query: 158 AFQDDRYLYMVMEYMPGGDLVNLMSNYDVPEKWAKFYTAEVVLALDAIHSMGLIHRDVKP 217
           ++  +  L++VME+M GG L ++++N  + E          + AL  +H+ G+IHRD+K 
Sbjct: 280 SYLVNDELWVVMEFMEGGALTDIVTNNRMDEVQIATVCRACLKALAFLHANGVIHRDIKS 459

Query: 218 DNMLLDKHGHLKLADFGTCMKMDETGMVHCDTAVGTPDYISPEVLKSQGGDGYYGRECDW 277
           D++LL   G +KL DFG C ++ +  +    + VGTP +++PEV+        YG E D 
Sbjct: 460 DSILLSHDGKVKLXDFGFCAQVTQD-LQKRKSLVGTPYWMAPEVISRLP----YGPEVDI 624

Query: 278 WSVGVFLFEMLVGDTPFYADSLVGTYSKIMD 308
           WS+G+ + EM+  + PF+ +  +    +I D
Sbjct: 625 WSLGIMVMEMIDAEPPFFNEPPLQAMRRIRD 717
>18921
          Length = 697

 Score = 96.7 bits (239), Expect = 6e-20,   Method: Compositional matrix adjust.
 Identities = 64/211 (30%), Positives = 111/211 (52%), Gaps = 2/211 (0%)
 Frame = +2

Query: 92  YDVVKVIGRGAFGEVQLVRHKASQKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANSPW 151
           +D++  +G G++G V    HK + +V A+K     ++   +D     +E  IM   +S +
Sbjct: 35  FDILGKLGEGSYGSVFKSLHKETGQVLAIK-----QVPVDTDLQEIIKEISIMQQCDSKY 199

Query: 152 VVQLFCAFQDDRYLYMVMEYMPGGDLVNLMS--NYDVPEKWAKFYTAEVVLALDAIHSMG 209
           +V+ + ++  +  L++VMEY   G + ++M   N  + E+         +  L  +HS  
Sbjct: 200 IVKYYGSYFKNTDLWIVMEYCGAGSVSDIMRLRNKTLVEREIATILYYTLKGLXYLHSRR 379

Query: 210 LIHRDVKPDNMLLDKHGHLKLADFGTCMKMDETGMVHCDTAVGTPDYISPEVLKSQGGDG 269
            IHRD+K  N+LL+  GH KLADFG   ++ +T M   +T +GTP +++PEV++  G   
Sbjct: 380 KIHRDIKAGNILLNNEGHAKLADFGVAGQLTDT-MAKRNTVIGTPYWMAPEVIQEIG--- 547

Query: 270 YYGRECDWWSVGVFLFEMLVGDTPFYADSLV 300
            Y    D WS+G+   EM  G  P    S++
Sbjct: 548 -YDCVADIWSLGITALEMAEGKPPVMETSIL 637
>00300
          Length = 2318

 Score = 96.3 bits (238), Expect = 8e-20,   Method: Compositional matrix adjust.
 Identities = 63/202 (31%), Positives = 100/202 (49%), Gaps = 4/202 (1%)
 Frame = -1

Query: 98   IGRGAFGEVQLVRHKASQKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANSPWVVQLFC 157
            IG G FG+V    + ++ ++ A+K + KF+           +E  I        +V+ + 
Sbjct: 1634 IGEGQFGKVYTAVNMSTGELMALKEM-KFQPNDLQQLREMCDEIKIFEGIQHENLVKYYG 1458

Query: 158  AFQDDRYLYMVMEYMPGGDLVNLMSNYDVPEKWAKFYTAEVVLALDAIHSMGLIHRDVKP 217
                   + M MEY   G  +   +   +PE   + YT E+VLA++ +H   ++HRD+K 
Sbjct: 1457 VEVHKDEMLMFMEYCDTGT-IEEAAKMGLPEYLIRRYTREIVLAVNHLHENSIVHRDIKG 1281

Query: 218  DNMLLDKHGHLKLADFGTCMKMDE----TGMVHCDTAVGTPDYISPEVLKSQGGDGYYGR 273
             N+ L  +GH+KL DFG  +K+       G  H    VGT  Y++PEV  +Q   G YGR
Sbjct: 1280 ANIFLTSNGHVKLGDFGCSVKLKSHTTMPGEFH--NLVGTTAYMAPEVF-TQNDQGGYGR 1110

Query: 274  ECDWWSVGVFLFEMLVGDTPFY 295
              D WS+G  + EM  G  P++
Sbjct: 1109 AADIWSLGCVVIEMATGKRPWH 1044
>14420
          Length = 528

 Score = 88.2 bits (217), Expect = 2e-17,   Method: Compositional matrix adjust.
 Identities = 49/146 (33%), Positives = 80/146 (54%)
 Frame = +2

Query: 149 SPWVVQLFCAFQDDRYLYMVMEYMPGGDLVNLMSNYDVPEKWAKFYTAEVVLALDAIHSM 208
           +P +V    ++     L++VME++ GG L ++++   + E        E + AL+ +H  
Sbjct: 77  NPNIVNYLDSYLVGEELWVVMEFLAGGSLTDVVTETCMDEGQIAAVCRECLQALEFLHEN 256

Query: 209 GLIHRDVKPDNMLLDKHGHLKLADFGTCMKMDETGMVHCDTAVGTPDYISPEVLKSQGGD 268
            +IHRD+K DN+LL   G +KL DFG C ++         T VGTP +++PEV+  +   
Sbjct: 257 QVIHRDIKSDNILLGMDGSVKLTDFGFCAQLSPEQSKR-STMVGTPYWMAPEVVTRK--- 424

Query: 269 GYYGRECDWWSVGVFLFEMLVGDTPF 294
             YG   D WS+GV   EM+ G+ P+
Sbjct: 425 -QYGPTVDIWSLGVMCIEMIEGEPPY 499
>01392
          Length = 1806

 Score = 86.7 bits (213), Expect = 6e-17,   Method: Composition-based stats.
 Identities = 63/189 (33%), Positives = 90/189 (47%), Gaps = 23/189 (12%)
 Frame = -1

Query: 188  EKWAKFYTAEVVLALDAIHSMGLIHRDVKPDNML---LDKHGHLKLADF----GTCMKMD 240
            E+ A      +  ALD +HS G+ HRD+KP+N+L   LD    +K+ DF    G     D
Sbjct: 1794 EREASLVVRHIARALDFLHSKGIAHRDLKPENILCEHLDDVVPVKICDFDLASGISCDGD 1615

Query: 241  ETGMVHCDTAVGTPDYISPEVLKSQGGDGY-YGRECDWWSVGVFLFEMLVGDTPFYA--- 296
             T      T VG+ +Y++PEV+ +  GD + Y + CD WS+G+ L+ ML G  PFY    
Sbjct: 1614 GTKTPELLTPVGSAEYMAPEVVDAWVGDSFSYDKRCDLWSLGIILYIMLCGYPPFYGQCG 1435

Query: 297  ------------DSLVGTYSKIMDHKNSLCFPEDTEISKHAKNLICAFLTDREVRLGRNG 344
                        D     ++ I D        E T IS  AK+LI   L  RE R  R  
Sbjct: 1434 EDCGWNRGEACHDCQDMLFNSIQDGHYKFPSQEWTSISSSAKDLIRHLLV-REPR-KRYS 1261

Query: 345  VEEIKQHPF 353
              ++ +HP+
Sbjct: 1260 AADVLKHPW 1234
>01707
          Length = 757

 Score = 86.3 bits (212), Expect = 8e-17,   Method: Compositional matrix adjust.
 Identities = 64/208 (30%), Positives = 106/208 (50%), Gaps = 5/208 (2%)
 Frame = +1

Query: 88  KAEDYDVVKVIGRGAFGEVQLVRHKASQKVYAMKLLSKFE---MIKRSDSAFFWEERDIM 144
           + E Y+ +  IG G++G V   R+K + ++ A+K   + E   +IK+        E  ++
Sbjct: 58  RMEKYEKIGKIGEGSYGVVFKCRNKETSQLVAIKKFVESEDDPLIKKIAM----REIRML 225

Query: 145 AFANSPWVVQLFCAFQDDRYLYMVMEYMPGGDLVNLMSNY--DVPEKWAKFYTAEVVLAL 202
                P +V+L   F+  + L++V +Y+    L+N +  Y   +PE   K    + +LA+
Sbjct: 226 KQLKHPNLVRLIEVFRRKKRLHLVFDYV-DHTLLNELDRYPRGLPEPMVKRIIYQTLLAV 402

Query: 203 DAIHSMGLIHRDVKPDNMLLDKHGHLKLADFGTCMKMDETGMVHCDTAVGTPDYISPEVL 262
           +  H    IHRDVKP+N+L+ + G +KL DFG    +   G  + D  V T  Y +PE+L
Sbjct: 403 NFCHQYNTIHRDVKPENILITRQGQVKLCDFGFARILTGPGDEYTD-YVATRWYRAPELL 579

Query: 263 KSQGGDGYYGRECDWWSVGVFLFEMLVG 290
               GD  YG   D W++G    E+L G
Sbjct: 580 V---GDTQYGPPVDVWAIGCVFAELLTG 654
>26560
          Length = 398

 Score = 84.0 bits (206), Expect = 4e-16,   Method: Composition-based stats.
 Identities = 43/108 (39%), Positives = 67/108 (62%), Gaps = 1/108 (0%)
 Frame = -1

Query: 188 EKWAKFYTAEVVLALDAIHSMGLIHRDVKPDNMLLDKHGHLKLADFGTCMKMDETGMVHC 247
           EK  +FY AEV+L L+ +HS  +++RD+KP N+LLD++GH++++D G      +      
Sbjct: 359 EKEVRFYAAEVMLGLEHMHSRFVVYRDLKPANILLDENGHVRISDLGLACDFSKK---RP 189

Query: 248 DTAVGTPDYISPEVL-KSQGGDGYYGRECDWWSVGVFLFEMLVGDTPF 294
             +VGT  Y++PEVL K Q     Y    DW+S G  L+++L G +PF
Sbjct: 188 HASVGTHGYMAPEVLMKGQS----YDSSADWFSFGCMLYKLLKGHSPF 57
>15910
          Length = 1361

 Score = 83.2 bits (204), Expect = 8e-16,   Method: Compositional matrix adjust.
 Identities = 53/139 (38%), Positives = 81/139 (58%), Gaps = 5/139 (3%)
 Frame = +2

Query: 196 AEVVLALDAIHSMGLIHRDVKPDNML---LDKHGHLKLADFGTCMKMDETGMVHCDTAVG 252
           ++++  +  IH+ G++HRD+KP+N+L   +     LKLADFG    ++    V   T  G
Sbjct: 485 SDILHGVQYIHANGVVHRDLKPENLLYECMTDDSKLKLADFGLSRIIEPE--VQMSTVCG 658

Query: 253 TPDYISPEVLKSQGGDGYYGRECDWWSVGVFLFEMLVGDTPFYADSLVGTYSKIMDHKNS 312
           TP Y +PEVLK   GD  Y    D WSVGV  + +L G  PF+A++    Y KI+  K  
Sbjct: 659 TPGYCAPEVLK---GDK-YTPSVDMWSVGVIAYILLCGYEPFFAENEFEMYRKII--KGE 820

Query: 313 LCFPED--TEISKHAKNLI 329
             F E+  +EIS++AK+++
Sbjct: 821 YKFDEEYWSEISENAKDVV 877
>13592
          Length = 980

 Score = 80.5 bits (197), Expect = 4e-15,   Method: Compositional matrix adjust.
 Identities = 61/204 (29%), Positives = 101/204 (49%), Gaps = 7/204 (3%)
 Frame = +2

Query: 98  IGRGAFGEVQLVRHKASQKVYAMKLLSKFEMIKRSDSAFF---WEERDIMAFANSPWVVQ 154
           IG+G FG+V    +  + ++ AMK ++    I+  ++       EE  I+       +V+
Sbjct: 8   IGQGRFGKVYTAVNNNTGELMAMKEIA----IQPGETRALKNVAEELKILEGIKHKNLVR 175

Query: 155 LFCAFQDDRYLYMVMEYMPGGDLVNLMS-NYDVPEKWAKFYTAEVVLALDAIHSMGLIHR 213
            +        L + ME    G L +L+     +PE  ++ +TA+++  +  +H  G++HR
Sbjct: 176 YYGIEVHREELLIFMELCSEGTLESLVELTGGLPEALSRRFTAQLLSGVAELHKHGIVHR 355

Query: 214 DVKPDNM-LLDKHGHLKLADFGTCMKMDETGMV--HCDTAVGTPDYISPEVLKSQGGDGY 270
           D+K  N+ L+D    LKL DFG+ +K+     V       VGT  Y++PEV      DG 
Sbjct: 356 DIKTANIFLVDGSNSLKLGDFGSAVKIQAHTTVPGELQGYVGTQAYMAPEVFTKTNSDG- 532

Query: 271 YGRECDWWSVGVFLFEMLVGDTPF 294
           +GR  D WSVG  + EM  G  P+
Sbjct: 533 HGRLADIWSVGCVVVEMASGKRPW 604
>09606
          Length = 1300

 Score = 80.1 bits (196), Expect = 5e-15,   Method: Compositional matrix adjust.
 Identities = 62/246 (25%), Positives = 114/246 (46%), Gaps = 22/246 (8%)
 Frame = -3

Query: 85   LQMKAEDYDVVKVIGRGAFGEVQLVRHKASQKVYAMKLLSKFEMIKRSDSAFFWEERDIM 144
            L  + E++ + + +G+G    +   R K +    A+  + K +  + +++       DI 
Sbjct: 1130 LITRMENFVLYEELGKGEHSIIYKGRRKGTINFVAIHCIEKCKRPEVTNTVRM--THDI- 960

Query: 145  AFANSPWVVQLFCAFQDDRYLYMVMEYMPGGDLVNLMS-NYDVPEKWAKFYTAEVVLALD 203
               + P VVQ    ++   +L++V+E   GG L ++++ ++ +PE   + +   +V  L 
Sbjct: 959  ---SHPNVVQFHEWYETSNHLWLVVELCTGGSLADILAQDHHLPETSIRDFGIHLVTGLH 789

Query: 204  AIHSMGLIHRDVKPDNMLLDKHGHLKLADFGTC-----------MKMDETG--------- 243
             IHS+G++  D++P  +LLD  G LK ADFG              K  E G         
Sbjct: 788  YIHSLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEAGDQWNIQSAE 609

Query: 244  -MVHCDTAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLFEMLVGDTPFYADSLVGT 302
             M+      G+P Y++PEV   QG +       D W++G   +EM  G  PF  ++   T
Sbjct: 608  EMMKQVPTSGSPTYMAPEVF--QGAEP--SIMSDLWALGCVFYEMFSGHPPFLGETYDIT 441

Query: 303  YSKIMD 308
              K+++
Sbjct: 440  KDKVLN 423
>13066
          Length = 551

 Score = 79.3 bits (194), Expect = 1e-14,   Method: Composition-based stats.
 Identities = 48/149 (32%), Positives = 80/149 (53%), Gaps = 3/149 (2%)
 Frame = +3

Query: 136 FFWEERDIMAFANSPWVVQLFCAFQDDRYLYMVMEYMPGGDLVNLMSNYD-VPEKWAKFY 194
           FF  E D++   + P+++Q+    Q     ++ M +   GDL+  +     V EK AK +
Sbjct: 114 FFPRELDLLTKLDHPYIIQIHSILQRXPKNFIFMRFAERGDLLTYIQEVGFVKEKQAKIW 293

Query: 195 TAEVVLALDAIHSMGLIHRDVKPDNMLLDKHGHLKLADFG-TCMKMDETGMVHCD-TAVG 252
             ++  AL+ +HS  + HRD+K +N+LL  H ++KLADFG  C  + E+G  +   T  G
Sbjct: 294 FYQMTTALNYLHSYDVAHRDLKCENILLSSHFNVKLADFGFACACITESGEKYMSRTYCG 473

Query: 253 TPDYISPEVLKSQGGDGYYGRECDWWSVG 281
           +  Y +PE++    G  Y  +  D WS+G
Sbjct: 474 SAAYAAPEIVY---GAPYAPKVADAWSLG 551
>26156
          Length = 479

 Score = 63.5 bits (153), Expect(2) = 3e-14,   Method: Compositional matrix adjust.
 Identities = 36/107 (33%), Positives = 66/107 (61%), Gaps = 4/107 (3%)
 Frame = -1

Query: 91  DYDVVKVIGRGAFGEVQLVRHKASQKVYAMKLLSKFEMIKRSDSAFFWEERDIMAF---A 147
           D+ +++VIGRG++ +V  V HK ++++YAMK++ K E++   D    W + +   F    
Sbjct: 386 DFLLLRVIGRGSYAKVLQVEHKRTKRIYAMKVIKK-ELVN-DDEDIDWVQTEKHVFETAT 213

Query: 148 NSPWVVQLFCAFQDDRYLYMVMEYMPGGDLV-NLMSNYDVPEKWAKF 193
           N P++V L   FQ +  L+ V+E++ GGDL+ ++     +PE+ A+F
Sbjct: 212 NYPFLVGLHSCFQSESRLFFVIEFVNGGDLMFHMQRQRRLPEEHARF 72

 Score = 34.3 bits (77), Expect(2) = 3e-14,   Method: Composition-based stats.
 Identities = 12/24 (50%), Positives = 20/24 (83%)
 Frame = -3

Query: 193 FYTAEVVLALDAIHSMGLIHRDVK 216
           FY+AE+ LAL+ +H  G+++RD+K
Sbjct: 75  FYSAEICLALNFLHKRGIVYRDLK 4
>12786
          Length = 460

 Score = 76.3 bits (186), Expect = 7e-14,   Method: Compositional matrix adjust.
 Identities = 47/121 (38%), Positives = 68/121 (56%), Gaps = 18/121 (14%)
 Frame = -3

Query: 192 KFYTAEVVLALDAIHSMGLIHRDVKPDNMLLDKHGHLKLADFGTC--MKMDETGMVHCDT 249
           KFY  E++ A+ A+H+ G+IH D+KP N +L   G+LKL DFG    ++ D+T ++  D+
Sbjct: 401 KFYWREMLRAVKALHNEGVIHSDLKPANFML-VAGNLKLIDFGIANTLQQDKTSVLK-DS 228

Query: 250 AVGTPDYISPEVL---------KSQGGDGY-------YGRECDWWSVGVFLFEMLVGDTP 293
            VGTP Y+SPE +          S   DG+        G   D WS+G  L+ M+ G TP
Sbjct: 227 RVGTPSYMSPEAIMAACDDSADDSMEEDGHRTKPKYKVGVRSDVWSLGCILYNMVYGRTP 48

Query: 294 F 294
           F
Sbjct: 47  F 45
>13212
          Length = 1067

 Score = 75.9 bits (185), Expect = 1e-13,   Method: Compositional matrix adjust.
 Identities = 61/186 (32%), Positives = 90/186 (48%), Gaps = 5/186 (2%)
 Frame = -1

Query: 175  GDLVNLMSNYDVPEKWAK--FYTAEVVLALDAIHSMGLIHRDVKPDNMLLDKHGHLKLAD 232
            G L ++M + + P   A+  +   E+ +ALD +H   +IHRD+K  N+LL   G +KLAD
Sbjct: 1028 GALDSIMVDLEKPMTEAQICYVCHEMCMALDFLHRHHVIHRDIKAGNVLLTIDGEVKLAD 849

Query: 233  FGTCMKMDETGMVHCDTAVGTPDYISPEVLKSQG-GDGYYGRECDWWSVGVFLFEMLVGD 291
            FG   K  +T     DT +GTP +++PEV+  +   D  Y  + D WS+GV L E    +
Sbjct: 848  FGVSAKNTQTQQKR-DTFIGTPYWMAPEVVLCETLKDTPYDFKADIWSLGVTLIEFAQIE 672

Query: 292  TPFYADSLVGTYSKIMDHKNSLCFPEDTEISKHAKNLICAFLTDREVRLG--RNGVEEIK 349
             P      +    KI  HK+    P   E  K    L   F+    V+    R    E+ 
Sbjct: 671  PPNKEMHPMRVLIKI--HKSD---PPTLEKPKKWTKLFKDFIAKCLVKDPNLRPTAAELL 507

Query: 350  QHPFFK 355
            +HPF K
Sbjct: 506  EHPFMK 489
>01718
          Length = 959

 Score = 75.1 bits (183), Expect = 2e-13,   Method: Compositional matrix adjust.
 Identities = 58/200 (29%), Positives = 94/200 (47%), Gaps = 10/200 (5%)
 Frame = +3

Query: 98  IGRGAFGEVQLVRHKASQKVYAMKLLS----KFEMIKRSDSAFFWEERDIMAFANSPWVV 153
           IG G F EV  V H+ + +V A+K+ +    +  M++        +  +I+ F       
Sbjct: 171 IGAGFFSEVFKVTHRITGQVMALKMNTMTSNRHNMLREVQLLNRLQHANILRFMG----- 335

Query: 154 QLFCAFQDDRYLYMVMEYMPGGDLVNLMSNYDVPEKWAKFYTAEVVLA--LDAIHSMGLI 211
              C  +    L+ + EY+P G+L  L+   D    W +     + LA  LD +HS   I
Sbjct: 336 --VCVHEGQ--LHALTEYIPSGNLEQLLEKKDEELPWTQRIQLTLGLARGLDYLHSTRFI 503

Query: 212 HRDVKPDNMLL---DKHG-HLKLADFGTCMKMDETGMVHCDTAVGTPDYISPEVLKSQGG 267
           HRD+   N+L+   D HG H  +ADFG   K+ +         VG+P +++PEVL     
Sbjct: 504 HRDLTSKNILIRREDNHGYHAVIADFGLATKIPDPLDKEKLPTVGSPYWMAPEVLNGH-- 677

Query: 268 DGYYGRECDWWSVGVFLFEM 287
             +Y    D +SVG+ + E+
Sbjct: 678 --FYNERADLFSVGIIMCEI 731
>17975
          Length = 449

 Score = 74.7 bits (182), Expect = 2e-13,   Method: Composition-based stats.
 Identities = 47/140 (33%), Positives = 79/140 (56%), Gaps = 5/140 (3%)
 Frame = +3

Query: 103 FGEVQLVRHKASQKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANSPWVVQLFCAFQDD 162
           F  V+L RH  + +  A+K++ K ++ + S S  F E R  M     P VV+L+      
Sbjct: 6   FAVVKLARHVFTGEKVAVKVIDKTKLDEVSRSHLFQEVR-CMKLVQHPNVVRLYEVIDTQ 182

Query: 163 RYLYMVMEYMPGGDLVNLMSNYD--VPEKWAKFYTAEVVLALDAIHSMGLIHRDVKPDNM 220
             LY+++E   GGD+ + +  +   + EK AK Y  ++V A+   H + ++HRD+KP+N+
Sbjct: 183 TKLYLILELGDGGDMYDYIMRHSGGLEEKLAKRYFRQIVEAISYCHKLHVVHRDLKPENV 362

Query: 221 L-LDKHGHLKLADFG--TCM 237
           +  +K G +KL DFG  TC+
Sbjct: 363 VFFEKPGLVKLTDFGFSTCL 422
>19094
          Length = 898

 Score = 70.5 bits (171), Expect = 5e-12,   Method: Composition-based stats.
 Identities = 36/87 (41%), Positives = 53/87 (60%)
 Frame = +1

Query: 205 IHSMGLIHRDVKPDNMLLDKHGHLKLADFGTCMKMDETGMVHCDTAVGTPDYISPEVLKS 264
           +HS   IHRD+K  N+LL+  GH KLADFG   ++ +T M   +T +GTP +++PEV++ 
Sbjct: 106 LHSRRKIHRDIKAGNILLNNEGHAKLADFGVAGQLTDT-MAKRNTVIGTPYWMAPEVIQE 282

Query: 265 QGGDGYYGRECDWWSVGVFLFEMLVGD 291
            G    Y    D WS+G+   EM  G+
Sbjct: 283 IG----YDCVADIWSLGITALEMAEGN 351
>26711
          Length = 405

 Score = 68.6 bits (166), Expect = 2e-11,   Method: Composition-based stats.
 Identities = 48/140 (34%), Positives = 71/140 (50%), Gaps = 7/140 (5%)
 Frame = -2

Query: 197 EVVLALDAIHSMGLIHRDVKPDNMLL--DKHGHLKLADFGTCMKM---DETGMVHCDTAV 251
           +V+  L  +H+ G++H D+KP N+LL  DK   ++L DFG   K+    ET + H     
Sbjct: 392 QVLDILQHVHAQGVVHMDLKPSNLLLSGDKLDSVQLIDFGLARKLYPPQETFLNH----- 228

Query: 252 GTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLFEMLVGDTPFYADSLVGTYSKIM--DH 309
           GTP + SPE L  +          D W VGV  + +L G +PF ADS   +  K    D 
Sbjct: 227 GTPGFTSPEALDVKP----ISTASDVWGVGVLAYILLSGQSPFQADSATESLKKTQTCDW 60

Query: 310 KNSLCFPEDTEISKHAKNLI 329
              +C P  + +S+ AK+ I
Sbjct: 59  SFDVC-PSFSNMSQDAKDFI 3
>01060
          Length = 1800

 Score = 68.6 bits (166), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 61/218 (27%), Positives = 94/218 (43%), Gaps = 8/218 (3%)
 Frame = +1

Query: 98  IGRGAFGEVQLVRHKASQKVYAMKLLSKFEMIKRSDSAFFWEERDIMAF--ANSPWVVQL 155
           IG G +G V   RH+A+ +  AMK   K  +    D       R+I          +V L
Sbjct: 97  IGEGTYGVVYKCRHRATGRKLAMK---KIRLRGSEDGVPSSAIREIAMLRELRHTNIVCL 267

Query: 156 FCAFQDDRYLYMVMEYMPGGDLVNLMSNYDVPE------KWAKFYTAEVVLALDAIHSMG 209
                +D  L++V E++   DL   +  +  PE      +  K Y  ++V  +   H   
Sbjct: 268 EDVIMEDERLFLVFEFL-SMDLKMYIDKF--PEGVVLDRRLVKSYVFQIVTGIXFCHQRR 438

Query: 210 LIHRDVKPDNMLLDKHGHLKLADFGTCMKMDETGMVHCDTAVGTPDYISPEVLKSQGGDG 269
           ++HRD+KP N+L++  G +K+ADFG           +    V T  Y +PE+L    G  
Sbjct: 439 IVHRDLKPQNLLINHTGAIKIADFGMARTFALPVRAYTHEVV-TLWYRAPEILM---GAS 606

Query: 270 YYGRECDWWSVGVFLFEMLVGDTPFYADSLVGTYSKIM 307
            Y    D WS+G    +ML+    F  DS +    KI 
Sbjct: 607 KYSTPVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIF 720
>01756
          Length = 1858

 Score = 67.8 bits (164), Expect = 3e-11,   Method: Compositional matrix adjust.
 Identities = 70/211 (33%), Positives = 98/211 (46%), Gaps = 15/211 (7%)
 Frame = -3

Query: 92   YDVVKVIGRGAFGEVQLVRHKASQKVYAMK-LLSKFEMIKRSDSAFFWEERDIMAFANSP 150
            Y+ +  IG+G FGEV   R K +++V AMK +L   E      +A    E  I+   N  
Sbjct: 1736 YEKLAKIGQGTFGEVFKARCKKTKQVVAMKKVLMDNEKEGFPITAL--REIKILQLLNHE 1563

Query: 151  WVVQLF--C---AFQDDRY---LYMVMEYMPGGDLVNLMSN----YDVPEKWAKFYTAEV 198
             VV L   C   A   +RY    Y+V E+    DL  L+SN    +++PE   K    ++
Sbjct: 1562 NVVDLIEICSTKATSANRYKSMFYLVFEFCEH-DLAGLLSNMSVVFNLPE--IKEVMKQL 1392

Query: 199  VLALDAIHSMGLIHRDVKPDNMLLDKHGHLKLADFGT--CMKMDETGMVHCDTAVGTPDY 256
            +  L  IH   ++HRD+K  N+L+ K G LKLADFG      ++          V T  Y
Sbjct: 1391 MNGLYYIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRVVTLWY 1212

Query: 257  ISPEVLKSQGGDGYYGRECDWWSVGVFLFEM 287
              PE+L    GD  Y    D W  G  + EM
Sbjct: 1211 RPPELLL---GDRNYSTAIDQWGAGCIMAEM 1128
>14126
          Length = 1265

 Score = 67.0 bits (162), Expect = 5e-11,   Method: Compositional matrix adjust.
 Identities = 88/315 (27%), Positives = 129/315 (40%), Gaps = 37/315 (11%)
 Frame = +3

Query: 92  YDVVKVIGRGAFGEVQLVRHKASQKVY-AMKLLSKFEMIKRSDSAFFWEERDIMAFAN-- 148
           Y+ V VIG GA+G V   R   +Q  + AMK   +  +    +       R+I       
Sbjct: 195 YEEVAVIGNGAYGTVYKARDLRNQGEFVAMK---RIRLNNTEEGMPMMAIREISMLKQLE 365

Query: 149 ---SPWVVQLFCAFQD---DR--YLYMVMEYMPGGDLVNLMSNYDVPEKWA---KFYTAE 197
               P VV+L     +   DR   L +V EY+   DL   ++    P       K    +
Sbjct: 366 QYEHPNVVRLLDVSHNTITDREIRLNLVFEYIEH-DLATYLAKCPSPGLGPDRIKDLMLQ 542

Query: 198 VVLALDAIHSMGLIHRDVKPDNMLLDKHGHLKLADFGTCMKMDETGMVHCDTAVGTPDYI 257
           ++  +D +HS  ++HRD+KP N+L+ K G LKLADFG  +    +  +   T V T  Y 
Sbjct: 543 LLNGVDFLHSNRIVHRDLKPQNLLISKDGRLKLADFG--LARIYSFHMALTTVVVTLWYR 716

Query: 258 SPEVLKSQGGDGYYGRECDWWSVGVFLFEMLVGDTPFYADSLVGTYSKIMD--------- 308
           SPEVL        YG   D WS G    E+      F   S      KI +         
Sbjct: 717 SPEVLMQ----AEYGTSVDIWSCGCIFAELFTRRALFKGSSEFDQLKKIFEVIGLPPAGD 884

Query: 309 -------HKNSL----CFPEDT---EISKHAKNLICAFLTDREVRLGRNGVEEIKQHPFF 354
                  H+NS       P  T   E+   AK+L+   L  +  R  R    E   HP+ 
Sbjct: 885 WPEGVSVHRNSFRPTPPVPLQTLVPEMDPQAKDLMEKMLVFKSGR--RISSRESLLHPYL 1058

Query: 355 KNDQWNWDNIRETAA 369
           ++D    D+IR +++
Sbjct: 1059RDD---LDSIRTSSS 1094
>00486
          Length = 797

 Score = 66.6 bits (161), Expect = 6e-11,   Method: Composition-based stats.
 Identities = 43/130 (33%), Positives = 63/130 (48%), Gaps = 3/130 (2%)
 Frame = -2

Query: 249 TAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLFEMLVGDTPFYADSLVGTYSKIMD 308
           T  GT +Y++PE+L   G    +G+  DWWS+G  +++ML G  PF A++   T  KI+ 
Sbjct: 781 TFCGTIEYMAPEILTRTG----HGKAVDWWSLGALMYDMLTGSPPFTAENRKKTIDKIL- 617

Query: 309 HKNSLCFPEDTEISKHAKNLICAFLTDREV-RL--GRNGVEEIKQHPFFKNDQWNWDNIR 365
            K  L  P    ++  A+ LI   L      RL  G +    IK H FF+N  W    +R
Sbjct: 616 -KGKLNLP--PYLTNEARGLIKKLLRKNPAERLGGGHDDSGPIKDHQFFRNTNWALLALR 446

Query: 366 ETAAPVVPEL 375
               P  P +
Sbjct: 445 RAEPPFRPNV 416
>06405
          Length = 1965

 Score = 66.6 bits (161), Expect = 7e-11,   Method: Compositional matrix adjust.
 Identities = 58/211 (27%), Positives = 91/211 (43%), Gaps = 5/211 (2%)
 Frame = +1

Query: 98  IGRGAFGEVQLVRHKASQKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANSPWVVQLFC 157
           +G G +G+V     K   K+ A+K L +  M        F EE  IM     P +VQL  
Sbjct: 283 LGGGQYGDVYEAMWKRYNKIVAVKTLKEDTMALND----FLEEAAIMKEMKHPNLVQLLG 450

Query: 158 AFQDDRYLYMVMEYMPGGDLVNLMSNYDVPEKW--AKFYTA-EVVLALDAIHSMGLIHRD 214
               +   Y+V E+MP G+L++ + +    E    A  Y A ++   +  + +   IHRD
Sbjct: 451 VCTREPPFYIVTEFMPHGNLLDYLRSSTREENGPTALMYMATQIASGMAYLETKNFIHRD 630

Query: 215 VKPDNMLLDKHGHLKLADFGTCMKM-DETGMVHCDTAVGTPDYISPEVLKSQGGDGYYGR 273
           +   N L+     +K+ADFG    M D+T   H         + +PE L        +  
Sbjct: 631 LAARNCLVADSNMVKVADFGLARLMKDDTYTAHIGAKFPI-KWTAPEGLAFN----RFST 795

Query: 274 ECDWWSVGVFLFEMLV-GDTPFYADSLVGTY 303
             D W+ GV L+E+   G +P+    L   Y
Sbjct: 796 RSDIWAFGVLLWELATYGMSPYPGVELTEVY 888
>05015
          Length = 894

 Score = 48.9 bits (115), Expect(2) = 9e-11,   Method: Compositional matrix adjust.
 Identities = 31/88 (35%), Positives = 47/88 (53%)
 Frame = +3

Query: 1069 ELKSEREKLTQQMIKYQKELNEMQAQIAEESQIRIELQMTLDSKDSDIEQLRSQLQALHI 1128
            EL  EREK  + + K Q+++ E Q  + EES  R  LQM +D+KDS+IEQLR     L +
Sbjct: 627  ELTMEREKYNKMVEKMQRDVAEAQQNVYEESLSRQRLQMEMDAKDSEIEQLR-----LKL 791

Query: 1129 GMDSSSIGSGPGDAEPDDGFPESRLEGW 1156
             + ++ + S       ++   E    GW
Sbjct: 792  SLFNADVTSTHSTGSLEESVVEESTSGW 875

 Score = 37.0 bits (84), Expect(2) = 9e-11,   Method: Compositional matrix adjust.
 Identities = 21/39 (53%), Positives = 28/39 (71%), Gaps = 5/39 (12%)
 Frame = +2

Query: 1032 TQAVNKLAEIMNRKEPVKRGS-----DTDVRRKEKENRK 1065
            +QAVNKLAEIMNRKE  + G       +D++RKEK+ R+
Sbjct: 500  SQAVNKLAEIMNRKEFRRGGGKDKAVGSDLKRKEKDLRR 616
>16708
          Length = 1397

 Score = 65.5 bits (158), Expect = 1e-10,   Method: Composition-based stats.
 Identities = 44/156 (28%), Positives = 80/156 (51%), Gaps = 15/156 (9%)
 Frame = -1

Query: 94   VVKVIGRGAFGEVQLVRHKASQKVYAMKL-------LSKFEMIKRSDSAFFWEERDIMAF 146
            +++V+G+G FG+V   R  ++ +  A+K        L + E + R +  F+      +A 
Sbjct: 1391 ILQVLGKGVFGKVYEARLLSTHEKAALKTSILCHHSLDEVEALGRIEGGFY------LAQ 1230

Query: 147  ANSPWVVQLFCAFQDDRYLYMVMEYMPGGDLVNLMSNY---DVPEKWAK-----FYTAEV 198
                WV  L   F     + +++ +   G L N+ ++Y   ++P +W+          + 
Sbjct: 1229 MFGAWVTCL--PFPK---MNILLHFYEMGPLCNVYAHYKNKEMPIRWSNPAMVCCIAGQX 1065

Query: 199  VLALDAIHSMGLIHRDVKPDNMLLDKHGHLKLADFG 234
            V AL+ IH +G++H DVK DN+L+D HG+ KL D+G
Sbjct: 1064 VCALEHIHELGVVHMDVKADNVLVDAHGNCKLTDYG 957
>17932
          Length = 597

 Score = 65.1 bits (157), Expect = 2e-10,   Method: Composition-based stats.
 Identities = 37/105 (35%), Positives = 54/105 (51%), Gaps = 4/105 (3%)
 Frame = -3

Query: 316 PEDTEISKHAKNLICAFLTDREVRLGRNGVEEIKQHPFFKNDQWNWDNIRETAAPVVPEL 375
           P  + +SK A++LI   L+D + RLG     E++QHPFFK    +W NIR    P VP +
Sbjct: 475 PPHSSVSKEARDLISQLLSDGKSRLGW---PELQQHPFFKT--VDWANIRNAMPPYVPSI 311

Query: 376 XXXXXXXXXXXXXXXKG--DVETF--PIPKAFVGNQLPFIGFTYF 416
                          +   ++++F  P  + F G  LPF+GFTYF
Sbjct: 310 SSLDDTSHFDEVEKARPAPNIDSFHQPSSRDFTGRHLPFVGFTYF 176

 Score = 48.1 bits (113), Expect = 2e-05,   Method: Composition-based stats.
 Identities = 22/51 (43%), Positives = 31/51 (60%), Gaps = 2/51 (3%)
 Frame = -2

Query: 277 WWSVGVFLFEMLVGDTPFYAD--SLVGTYSKIMDHKNSLCFPEDTEISKHA 325
           WWS+GV  +EML G TPF  D  S+V TY+ IM++K +   P    + + A
Sbjct: 596 WWSLGVCAYEMLFGCTPFTDDDGSMVATYNNIMNYKTNSSSPSQQRVQRGA 444
>18663
          Length = 600

 Score = 63.2 bits (152), Expect = 7e-10,   Method: Compositional matrix adjust.
 Identities = 43/139 (30%), Positives = 63/139 (45%), Gaps = 12/139 (8%)
 Frame = +2

Query: 249 TAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLFEMLVGDTPFYADSLVGTYSKIMD 308
           T  GTP+YI+PE+L+ +     YG   DWW++GV L+EML G +PF    + G       
Sbjct: 5   TFCGTPNYIAPEILRGED----YGFSVDWWALGVLLYEMLAGRSPF---DIAGASENPDQ 163

Query: 309 HKNSLCFPEDTE--------ISKHAKNLICAFLTDREV-RLG---RNGVEEIKQHPFFKN 356
           +     F    E        +S  A +++  FL      RLG    +   +I  HPFFK 
Sbjct: 164 NTEDYLFQVILEKTIRIPRSLSVKAASVLKGFLNKNPADRLGCHRESAFMDIVNHPFFKV 343

Query: 357 DQWNWDNIRETAAPVVPEL 375
             W     ++ + P  P L
Sbjct: 344 IDWEMLERKQVSPPFKPRL 400
>21079
          Length = 878

 Score = 61.6 bits (148), Expect = 2e-09,   Method: Composition-based stats.
 Identities = 38/148 (25%), Positives = 74/148 (50%), Gaps = 4/148 (2%)
 Frame = +1

Query: 150 PWVVQLFCAFQDDRYLYMVMEYMPGGDLVN--LMSNYDVPEKWAKFYTAEVVLALDAIHS 207
           P ++ L+ AF+  R + +VME++  G+L    +  ++ + E+    +  ++   +  +H+
Sbjct: 4   PKLLMLWDAFEAPRTMVLVMEFVGAGELFERVIRDDFVLTERDCVHFVRQICSGVGYMHT 183

Query: 208 MGLIHRDVKPDNMLL--DKHGHLKLADFGTCMKMDETGMVHCDTAVGTPDYISPEVLKSQ 265
             ++H D+KP+N+L   D    +K+ DFG          +      GTP++I+PEV+   
Sbjct: 184 QSILHLDLKPENVLCVSDNSNQIKIIDFGLARFYKPGDSLQ--VLFGTPEFIAPEVVNYD 357

Query: 266 GGDGYYGRECDWWSVGVFLFEMLVGDTP 293
                     D WS+GV  + +L G +P
Sbjct: 358 ----EINFTTDMWSIGVICYILLSGLSP 429
>04591
          Length = 1117

 Score = 61.2 bits (147), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 51/146 (34%), Positives = 71/146 (48%), Gaps = 10/146 (6%)
 Frame = -2

Query: 152  VVQL--FCAFQDDRY------LYMVMEYMPGGDLVNLMSNYDVPEKWA--KFYTAEVVLA 201
            VVQL   C  Q   Y       Y++ EY    DL  L++N  V    A  K   ++++  
Sbjct: 1035 VVQLQEICHTQAGPYNRYKSTFYLIFEYC-DYDLAGLLNNLRVKFSLADKKNLMSQLLNG 859

Query: 202  LDAIHSMGLIHRDVKPDNMLLDKHGHLKLADFGTCMKMDETGMVHCDTAVGTPDYISPEV 261
            L  IH+  ++HRD+K  N+LL + G LKLADFG      ++  +     V T  Y  PE+
Sbjct: 858  LFYIHTKQILHRDIKAANILLTRDGVLKLADFGLSRPWVKSKRL--TNRVVTLWYRPPEL 685

Query: 262  LKSQGGDGYYGRECDWWSVGVFLFEM 287
            L    G+  YG E D W VG  + EM
Sbjct: 684  LL---GEREYGPEIDMWGVGCIMAEM 616
>25019
          Length = 730

 Score = 60.1 bits (144), Expect = 5e-09,   Method: Composition-based stats.
 Identities = 30/64 (46%), Positives = 40/64 (62%)
 Frame = +3

Query: 218 DNMLLDKHGHLKLADFGTCMKMDETGMVHCDTAVGTPDYISPEVLKSQGGDGYYGRECDW 277
           +N+LLDK GH+KL DFG C K   TG     T  GT +Y++PE+L   G    +G+  DW
Sbjct: 261 ENVLLDKDGHVKLTDFGLC-KEAITGTRVTHTFCGTIEYMAPEILTRTG----HGKAVDW 425

Query: 278 WSVG 281
           WS+G
Sbjct: 426 WSLG 437
>21433
          Length = 590

 Score = 58.2 bits (139), Expect = 2e-08,   Method: Composition-based stats.
 Identities = 38/101 (37%), Positives = 55/101 (54%)
 Frame = +2

Query: 194 YTAEVVLALDAIHSMGLIHRDVKPDNMLLDKHGHLKLADFGTCMKMDETGMVHCDTAVGT 253
           Y  ++  AL+  H   +IHRD+KP+N+LL   G LK+ADFG  +    +      T  GT
Sbjct: 182 YIYQLSSALEYCHYRKVIHRDIKPENLLLGLKGDLKIADFGWSVHAPSSRRT---TMCGT 352

Query: 254 PDYISPEVLKSQGGDGYYGRECDWWSVGVFLFEMLVGDTPF 294
            DY+ PE+++ +  D       D WS+GV  +E LVG  P 
Sbjct: 353 LDYLPPEMVEGKTHD----ENVDLWSLGVLCYEFLVGTPPL 463
>19761
          Length = 473

 Score = 55.8 bits (133), Expect = 1e-07,   Method: Composition-based stats.
 Identities = 33/105 (31%), Positives = 57/105 (54%), Gaps = 3/105 (2%)
 Frame = -3

Query: 186 VPEKWAKFYTAEVVLALDAIHSMG--LIHRDVKPDNMLLDKHGHLKLADFGTCMKMDETG 243
           +PE+    +  +   AL+ +H+    ++HRD+KP N+ + + G ++L D G   K+  TG
Sbjct: 432 LPERLIVCWLMQTASALNYMHTHTPVILHRDLKPQNIYVTEKGDVRLGDLGLARKL--TG 259

Query: 244 MVHCDTA-VGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLFEM 287
                T+ VGT  Y+SPE+L  Q     Y  + D WS+G   +++
Sbjct: 258 PADFATSQVGTIMYLSPEILSQQP----YNSKSDIWSLGCVFYDI 136
>03508
          Length = 1463

 Score = 55.5 bits (132), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 38/118 (32%), Positives = 61/118 (51%), Gaps = 1/118 (0%)
 Frame = +1

Query: 177 LVNLMSNYDVPEKWAKFYTAEVVLALDAIHSMGLIHRDVKPDNMLLD-KHGHLKLADFGT 235
           L    ++YD+     +FY  E++ ALD  HSMG++HRDVKP N+++D ++  L+L D+G 
Sbjct: 850 LYQTFTDYDI-----RFYLYELMKALDFCHSMGIMHRDVKPHNVMIDHENKKLRLIDWGL 1014

Query: 236 CMKMDETGMVHCDTAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLFEMLVGDTP 293
             +    GM + +  V +  +  PE+L        Y    D WS+G     M+    P
Sbjct: 1015A-EFYHPGMEY-NVRVASRYFKGPELLLDYQM---YDYSLDMWSLGCMFASMIFRKEP 1173
>14748
          Length = 606

 Score = 55.5 bits (132), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 47/173 (27%), Positives = 91/173 (52%), Gaps = 4/173 (2%)
 Frame = +3

Query: 486 EEITLRKSVESTLRQLEREKALLQHKNAEYQRKADHEADKKRNLENDVNSLKDQLEDLKK 545
           EE+TL+    + LR +ER  A+L+H+  E QR+ D E + ++  E  V   + +++ +++
Sbjct: 57  EEMTLK----TELRDMERSMAMLKHELKESQRRLDQEVEGRKAFEKRVMDKEREIDAMRR 224

Query: 546 R----NQSSQISTEKVNQLQKQLDEANALLRTESDTAARLRKTQAESSKQIQQLESNNRD 601
           +    N+ S  S+E++  ++K L+EAN  LRTE D A + +K  ++  +++   E N  +
Sbjct: 225 KGQEINRDSVQSSERLASVEKSLNEANVKLRTEMDHANKQKKAMSDMQQRLMNAEQNYGE 404

Query: 602 LQDKNCXXXXXXXXXXXXFINLQSALESERRDRTHGSEIINDLQGRISGLEED 654
           L  +               + LQ++L+ ER  R+       +L  RI  L+++
Sbjct: 405 LTGRYQDLNALKQRMETEVLTLQASLDVERNARSQEVAHTMELNERIKALQDE 563
>01966
          Length = 1735

 Score = 48.1 bits (113), Expect(2) = 2e-07,   Method: Composition-based stats.
 Identities = 37/133 (27%), Positives = 63/133 (47%), Gaps = 8/133 (6%)
 Frame = -1

Query: 110  RHKASQKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFAN--SPWVVQLFCAFQDDRYLYM 167
            RH+A+ +  AMK   K  +    D       R+I          +V L     +D  L++
Sbjct: 1651 RHRATGRKLAMK---KIRLRGSEDGVPSSAIREIAMLRELRHTNIVCLEDVIMEDERLFL 1481

Query: 168  VMEYMPGGDLVNLMSNYDVPE------KWAKFYTAEVVLALDAIHSMGLIHRDVKPDNML 221
            V E++   DL   +  +  PE      +  K Y  ++V  ++  H   ++HRD+KP N+L
Sbjct: 1480 VFEFL-SMDLKMYIDKF--PEGVVLDRRLVKSYVFQIVTGINFCHQRRIVHRDLKPQNLL 1310

Query: 222  LDKHGHLKLADFG 234
            ++  G +K+ADFG
Sbjct: 1309 INHTGAIKIADFG 1271

 Score = 26.2 bits (56), Expect(2) = 2e-07,   Method: Composition-based stats.
 Identities = 17/60 (28%), Positives = 22/60 (36%)
 Frame = -3

Query: 247  CDTAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLFEMLVGDTPFYADSLVGTYSKI 306
            CD  V  P        +   G   Y    D WS+G    +ML+    F  DS +    KI
Sbjct: 1223 CDLVVPGP--------RDPHGASKYSTPVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKI 1068
>27546
          Length = 426

 Score = 55.1 bits (131), Expect = 2e-07,   Method: Composition-based stats.
 Identities = 30/100 (30%), Positives = 55/100 (55%), Gaps = 1/100 (1%)
 Frame = -1

Query: 136 FFWEERDIMAFANSPWVVQLFCAFQDDRYLYMVMEYMPGGDLVN-LMSNYDVPEKWAKFY 194
           FF  E +I+   + P ++Q+    Q    +++ M Y   GD+++ +     + E   K +
Sbjct: 342 FFPRELEILTRLDHPNIIQIHSILQRGPKIFIFMRYAEKGDMLSHIKKTGPIDEAQTKVW 163

Query: 195 TAEVVLALDAIHSMGLIHRDVKPDNMLLDKHGHLKLADFG 234
             ++  AL  +HS  + HRD+K +N+LL K  ++K+ADFG
Sbjct: 162 FFQMAKALQYLHSHDIAHRDLKCENILLSKRLNVKIADFG 43
>29581
          Length = 1278

 Score = 54.7 bits (130), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 43/132 (32%), Positives = 62/132 (46%), Gaps = 2/132 (1%)
 Frame = -2

Query: 165  LYMVMEYMPGGDLVNLMSNYDVP--EKWAKFYTAEVVLALDAIHSMGLIHRDVKPDNMLL 222
            L++VMEY    DL +L+ N   P  E   K    +++  L  +H   +IHRD+K  N+L+
Sbjct: 1124 LFLVMEYC-EQDLASLLDNMPAPFSESQVKCIVLQLLKGLRYLHEAFIIHRDLKVSNLLM 948

Query: 223  DKHGHLKLADFGTCMKMDETGMVHCDTAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGV 282
               G +K+ADFG      +         V T  Y +PE+L    G   +    D WS G 
Sbjct: 947  TDKGCVKIADFGLARNYGKPQKPMTPKVV-TLWYRAPELL---FGSKTHSTAIDMWSAGC 780

Query: 283  FLFEMLVGDTPF 294
             L E+L G  P 
Sbjct: 779  ILGELL-GHKPL 747
>11185
          Length = 473

 Score = 52.4 bits (124), Expect = 1e-06,   Method: Composition-based stats.
 Identities = 36/114 (31%), Positives = 51/114 (44%), Gaps = 21/114 (18%)
 Frame = +1

Query: 198 VVLALDAIHSMGLIHRDVKPDNMLLDKHGHLKLADFGTC-----------MKMDETG--- 243
           +V  L  IHS+G++  D++P  +LLD  G LK ADFG              K  E G   
Sbjct: 28  LVTGLHYIHSLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEAGDQW 207

Query: 244 -------MVHCDTAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLFEMLVG 290
                  M+      G+P Y++PEV   QG +       D W++G   +EM  G
Sbjct: 208 NIQSAEEMMKQVPTSGSPTYMAPEVF--QGAEPSI--MSDLWALGCVFYEMFSG 357
>00392
          Length = 668

 Score = 51.2 bits (121), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 49/210 (23%), Positives = 95/210 (45%), Gaps = 15/210 (7%)
 Frame = +3

Query: 137 FWEERDIMAFANSPWVVQLFCAFQDDRY-----LYMVMEYMPGGDLVNLMSNYDVPE-KW 190
           F EE +++     P +V+ F  +++  +     + +V E M  G L   +  +  P  K 
Sbjct: 72  FKEEAEMLKELQHPNIVRFFDYWEEHNHRNRKVIILVTELMTSGTLKTYLKRFKKPNVKI 251

Query: 191 AKFYTAEVVLALDAIHSMG--LIHRDVKPDNMLL-DKHGHLKLADFGTCMKMDETGMVHC 247
            K +  +V+  L  +H+    +IHRD+K DN+ +    G +K+ D G     +++     
Sbjct: 252 LKNWCRQVLKGLYFLHTRTPPVIHRDLKCDNIFITGPTGSVKIGDLGLATLKNQS---FA 422

Query: 248 DTAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLFEMLVGDTPFYADSLVGTYSKIM 307
            + +GTP++++PE+ +      +Y    D ++ G+ + EM   + P+   S     ++I 
Sbjct: 423 KSVIGTPEFMAPEMYEE-----HYDEAVDVYAFGMCMLEMASSEYPY---SECSNAAQIY 578

Query: 308 DHKNSLCFPED------TEISKHAKNLICA 331
               S   PE       TEI     + IC+
Sbjct: 579 KRVTSGVLPEALDKVAITEIRDIIHHCICS 668
>00715
          Length = 1788

 Score = 50.8 bits (120), Expect = 4e-06,   Method: Composition-based stats.
 Identities = 43/185 (23%), Positives = 78/185 (42%), Gaps = 23/185 (12%)
 Frame = +1

Query: 159 FQDDRYLYMVMEYMPGGDLVNLMSNY--DVPEKWAKFYTAEVVLALDAIHSMGLIHRDVK 216
           F+D  +L   MEY+   +L  +++++  D+          ++   L  +HS+ ++H D+K
Sbjct: 148 FEDGAWL--AMEYVGPLNLQTILNDHQQDIDSSMRLSLALQMARGLHYLHSINIVHLDLK 321

Query: 217 PDNMLLDKHGHLKLADFGTCMKMDETGM---------------------VHCDTAVGTPD 255
           P N LL +   L++ADFG C ++  TG+                        +   GT  
Sbjct: 322 PANCLLTRDLKLRIADFGCCHQLTPTGLDMGEREGGMAGNELELTPVQGAWKNELAGTLA 501

Query: 256 YISPEVLKSQGGDGYYGRECDWWSVGVFLFEMLVGDTPFYADSLVGTYSKIMDHKNSLCF 315
           Y +PE+LK            D +S+G+ L++M     P+          +++      C 
Sbjct: 502 YRAPELLKGLQPS----VRSDVYSLGITLWQMCTRQGPYEGVPAHAVVYQVVSKDLRPCP 669

Query: 316 PEDTE 320
           P  TE
Sbjct: 670 PPSTE 684
>17722
          Length = 680

 Score = 50.8 bits (120), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 35/106 (33%), Positives = 56/106 (52%), Gaps = 5/106 (4%)
 Frame = -3

Query: 275 CDWWSVGVFLFEMLVGDTPFYADSLVGTYSKIMDHKNSLCFPEDTEISKHAKNLICAFLT 334
            DWW  GV ++EM+ G  PFY       +  I+    ++ FP +  +S+ AK L+   L 
Sbjct: 678 VDWWGTGVVMYEMMCGRLPFYNRDHDVLFELIL--LQNVKFPRN--LSEEAKTLLSGLLA 511

Query: 335 -DREVRLGRN--GVEEIKQHPFFKNDQWNWDNI--RETAAPVVPEL 375
            + + RLG +   V EIK HPFF+    NWD++  ++   P  P++
Sbjct: 510 KNPKRRLGGSEADVTEIKTHPFFQCI--NWDDLAAKKITPPWKPDV 379
>28157
          Length = 400

 Score = 50.4 bits (119), Expect = 5e-06,   Method: Composition-based stats.
 Identities = 36/107 (33%), Positives = 58/107 (54%), Gaps = 8/107 (7%)
 Frame = +3

Query: 137 FWEERDIMAFANSPWVVQLFCAFQDDRYLYMVMEYMPGGDLVNLMSNYDVPEKW----AK 192
           F +E   ++  + P +V L+ A +D   + +VMEY  GG L N++       ++    A 
Sbjct: 51  FMQELKQLSRVSHPNIVCLYGACRD-HPVCLVMEYAEGGSLYNVLHGSGPQPQYTAAHAM 227

Query: 193 FYTAEVVLALDAIHSM---GLIHRDVKPDNMLLDKHG-HLKLADFGT 235
            +  +  L ++ +H M    LIHRD+KP N+LL + G  LK+ DFGT
Sbjct: 228 NWLLQCALGVEYLHGMKPKALIHRDLKPPNLLLIQCGTKLKICDFGT 368
>19301
          Length = 712

 Score = 48.1 bits (113), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 22/70 (31%), Positives = 44/70 (62%), Gaps = 1/70 (1%)
 Frame = +2

Query: 167 MVMEYMPGGDLVNLMSNY-DVPEKWAKFYTAEVVLALDAIHSMGLIHRDVKPDNMLLDKH 225
           ++MEY P G L  ++ +  ++P      ++ ++   ++ +HS  +IHRD+K  N+L+ K+
Sbjct: 500 IIMEYCPYGQLYEVLRDGKEIPPALVLDWSKQIASGMNYLHSHKIIHRDLKSPNVLVAKN 679

Query: 226 GHLKLADFGT 235
             +K++DFGT
Sbjct: 680 DVVKISDFGT 709
>07833
          Length = 1504

 Score = 47.8 bits (112), Expect = 3e-05,   Method: Composition-based stats.
 Identities = 39/169 (23%), Positives = 72/169 (42%), Gaps = 11/169 (6%)
 Frame = -3

Query: 137  FWEERDIMAFANSPWVVQLFCAFQDDRYLYMVMEYMPGGDLVNLM---SNYDVPEKWAKF 193
            F EE   +   N P V+ +         L ++ ++MP G L N +   S   V +  +  
Sbjct: 1478 FMEEFPRLRIFNHPNVLPVLACCNQPPNLVLISQFMPFGSLYNTLHGESGIVVDQNQSLR 1299

Query: 194  YTAEVVLALDAIHSMGLIHRDVKPDNMLLDKH--------GHLKLADFGTCMKMDETGMV 245
            +  ++   ++ +HSM        P+ +L  KH          + +AD+  C    E G V
Sbjct: 1298 FAMDIARGMEFLHSM----EPTIPNFLLTSKHVMIDEDLTARINMADY--CFSFHEKGKV 1137

Query: 246  HCDTAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLFEMLVGDTPF 294
            +      +P +++PE L+ +  D    R  D WS  + ++E+   + PF
Sbjct: 1136 Y------SPAWMAPEALQRRPDD-INTRAADMWSFAILMWELETREVPF 1011
>04852
          Length = 1462

 Score = 47.8 bits (112), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 43/151 (28%), Positives = 71/151 (47%), Gaps = 6/151 (3%)
 Frame = +1

Query: 173 PGGDLV---NLMSNYDVPEKWAKFYTAEVVLALDAIHSMGLIHRDVKPDNMLLDKHGHLK 229
           PGG ++   NL+S           Y  ++   ++ + S   IHRD+   N+L+ +   LK
Sbjct: 301 PGGHVIRRKNLLS-----------YAFQIARGMEFLASRKCIHRDLAARNVLVTEEHVLK 447

Query: 230 LADFGTCMKMDETGMVHCDTAVG--TPDYISPEVLKSQGGDGYYGRECDWWSVGVFLFEM 287
           +ADFG    +  TG  +   + G     +++PE L     D  Y  + D WS GV L+E+
Sbjct: 448 IADFG----LSRTGDYYKKRSGGRLPVKWMAPEALF----DMRYTTKSDVWSFGVVLWEI 603

Query: 288 L-VGDTPFYADSLVGTYSKIMDHKNSLCFPE 317
             +G  P+ +      YSK++D    +  PE
Sbjct: 604 FSLGGMPYASIPNEELYSKLLDDAYRMPRPE 696
>37602
          Length = 804

 Score = 47.0 bits (110), Expect = 5e-05,   Method: Composition-based stats.
 Identities = 28/86 (32%), Positives = 43/86 (50%), Gaps = 5/86 (5%)
 Frame = -1

Query: 153 VQLFCAFQDD----RYLYMVMEYMPGGDLVNLMS-NYDVPEKWAKFYTAEVVLALDAIHS 207
           +Q F  + D       L++ MEY  GG + ++      + E    F   E +  L  +H 
Sbjct: 342 IQTFVGYFDSYLRREKLWIAMEYCGGGSMQDIYHVTGPLTEPQIAFVCRETLKGLHYLHR 163

Query: 208 MGLIHRDVKPDNMLLDKHGHLKLADF 233
            G +HRD+K  N+LL + G +KLADF
Sbjct: 162 RGKMHRDIKGANILLTEEGDVKLADF 85
>38560
          Length = 479

 Score = 47.0 bits (110), Expect = 6e-05,   Method: Composition-based stats.
 Identities = 26/63 (41%), Positives = 34/63 (53%), Gaps = 1/63 (1%)
 Frame = -3

Query: 233 FGTCMKMDETGM-VHCDTAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLFEMLVGD 291
           FGT     + GM  H  T  G+P Y +PE++    G  Y G E D WS+GV L+ +L G 
Sbjct: 459 FGTLCA*PKGGMDHHLTTCCGSPAYAAPELIS---GLEYLGSEADIWSMGVLLYALLCGY 289

Query: 292 TPF 294
            PF
Sbjct: 288 LPF 280
>37063
          Length = 455

 Score = 46.6 bits (109), Expect = 7e-05,   Method: Composition-based stats.
 Identities = 28/84 (33%), Positives = 46/84 (54%), Gaps = 14/84 (16%)
 Frame = -2

Query: 215 VKPDNML---LDKHGHLKLADFGTCMKMDETGMVHCD----------TAVGTPDYISPEV 261
           +KP+N+L   LD+   LK+ DF      D    ++CD          T VG+ +Y++PEV
Sbjct: 454 LKPENILCEHLDEVVPLKICDF------DLASGINCDGDGTKTPELLTPVGSAEYMAPEV 293

Query: 262 LKSQGGDGY-YGRECDWWSVGVFL 284
           + +  G+ + Y + CD WS+G+ L
Sbjct: 292 VDAWVGESFSYDKRCDMWSLGIIL 221
>28638
          Length = 1458

 Score = 46.6 bits (109), Expect = 7e-05,   Method: Composition-based stats.
 Identities = 31/93 (33%), Positives = 45/93 (48%), Gaps = 2/93 (2%)
 Frame = -1

Query: 204 AIHSMGLIHRDVKPDNMLL--DKHGHLKLADFGTCMKMDETGMVHCDTAVGTPDYISPEV 261
           A   M +IH D+KP+N+LL   K   +K+ DFG+  ++ +    +  +      Y SPEV
Sbjct: 786 ATPEMNIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRF----YRSPEV 619

Query: 262 LKSQGGDGYYGRECDWWSVGVFLFEMLVGDTPF 294
           L        Y    D WS+G  L EM  G+ P 
Sbjct: 618 LLGVP----YDLAIDMWSLGCILVEMHTGEPPL 532
>11780
          Length = 1713

 Score = 45.4 bits (106), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 45/184 (24%), Positives = 87/184 (47%), Gaps = 4/184 (2%)
 Frame = +3

Query: 84  GLQMKAEDYDVVKVIGRGAFGEVQLVRHKASQKVYAMKLLSKFEMIKRSDSAFFWEERDI 143
           G  +  +D ++ + IG+G FG+V    ++  Q V   +L  K     R + +F  +E  +
Sbjct: 579 GWVIAXQDLEIGEAIGKGDFGDVYKGMYRG-QPVAIKQLKDK----DRGEQSFL-QEASV 740

Query: 144 MAFANSPWVVQLFCAFQDDRYLYMVMEYMPGGDLVNLMSNYD---VPEKWAKFYTAEVVL 200
           M       +V+L      +  +++V E+M  G+LV  + +     + +K    +  +   
Sbjct: 741 MTSLRHDNLVRLIGVVLGET-IFLVTEFMGKGNLVEYLRSRGRSVITKKDQINFATDTCA 917

Query: 201 ALDAIHSMGLIHRDVKPDNMLLDKHGHLKLADFGTCMKMDETGMVHCDTAVGTP-DYISP 259
           A++ + S  L+HRD+   N+L+   G  K++DFG     D +      T+V  P  + +P
Sbjct: 918 AMEYLESKRLVHRDLAARNVLVHDDGKAKVSDFGLAKFGDFS-----QTSVKFPIKWTAP 1082

Query: 260 EVLK 263
           E L+
Sbjct: 1083EALR 1094
>14116
          Length = 1017

 Score = 45.1 bits (105), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 38/137 (27%), Positives = 65/137 (47%), Gaps = 4/137 (2%)
 Frame = -1

Query: 156 FCAFQDDRYLYMVMEYMPGGDLVNLMSN--YDVPEKWAKFYTAEVVLALDAIHSMGLIHR 213
            C   DD  L +V+ +M  GDL+  + +  +    K    Y  ++   +D +  +  +HR
Sbjct: 423 ICLNLDDMPL-VVLPFMKHGDLLTYIRDDQHQPTIKDLIMYGVDIARGMDYLAGLKFVHR 247

Query: 214 DVKPDNMLLDKHGHLKLADFGTCMKMDETGMVHCDT--AVGTPDYISPEVLKSQGGDGYY 271
           D+   N +LD+  H+K+ADFG    + E      +   A     +++ E L+     G Y
Sbjct: 246 DLAARNCMLDEDFHVKVADFGLARDIYEKEYYSSENKKAKLPVKWMALESLEK----GNY 79

Query: 272 GRECDWWSVGVFLFEML 288
             + D WS GV L+E+L
Sbjct: 78  DSKTDVWSYGVVLWELL 28
>04138
          Length = 800

 Score = 44.7 bits (104), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 32/88 (36%), Positives = 41/88 (46%), Gaps = 2/88 (2%)
 Frame = +1

Query: 202 LDAIHSMGLIHRDVKPDNMLLDKHGHLKLADFGT--CMKMDETGMVHCDTAVGTPDYISP 259
           L  IH   ++HRD+K  N+L+ K G LKLADFG      ++          V T  Y  P
Sbjct: 52  LYYIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRVVTLWYRPP 231

Query: 260 EVLKSQGGDGYYGRECDWWSVGVFLFEM 287
           E+L    GD  Y    D W  G  + EM
Sbjct: 232 ELLL---GDRNYSTAIDQWGAGCIMAEM 306
>21808
          Length = 1011

 Score = 44.3 bits (103), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 41/166 (24%), Positives = 69/166 (41%), Gaps = 8/166 (4%)
 Frame = +1

Query: 137 FWEERDIMAFANSPWVVQLFCAFQDDRYLYMVMEYMPGGDLVNLMSNYDVPEKWAKFY-- 194
           F  E  IM     P ++QL+     D  ++++ E M  G L+  +       K       
Sbjct: 73  FLAEAQIMKKLRHPKLIQLYAVCTQDDPIFIITELMKNGSLLEFLQGKGRVLKLPALIDI 252

Query: 195 TAEVVLALDAIHSMGLIHRDVKPDNMLLDKHGHLKLADFGT--CMKMDETGMVHCDTAVG 252
            A++   +  + S   IHRD+   N+L+  +  +K+ADFG    +K DE      +  VG
Sbjct: 253 GAQIACGMAYLESQNYIHRDLAARNILVSDNNTVKIADFGLARVIKEDEY-----EARVG 417

Query: 253 T---PDYISPEVLKSQGGDGYYGRECDWWSVGVFLFEMLV-GDTPF 294
                 + +PE          +  + D WS G+ L E +  G  P+
Sbjct: 418 ARFPIKWTAPEAANYN----RFTIKSDVWSFGILLTETVTYGRVPY 543
>00638
          Length = 1595

 Score = 43.1 bits (100), Expect = 7e-04,   Method: Composition-based stats.
 Identities = 26/77 (33%), Positives = 42/77 (54%), Gaps = 5/77 (6%)
 Frame = +2

Query: 152 VVQLFCAFQD--DRYLYMVMEYMPGGDLVNL---MSNYDVPEKWAKFYTAEVVLALDAIH 206
           V+ L    +D   R   ++ E++   D   L    ++YD+     +FY  E++ ALD  H
Sbjct: 305 VITLLAIVKDPVSRTPALIFEHVNNTDFKQLYQTFTDYDI-----RFYLYELMKALDFCH 469

Query: 207 SMGLIHRDVKPDNMLLD 223
           SMG++HRDVKP   L++
Sbjct: 470 SMGIMHRDVKPSPPLVN 520
>32359
          Length = 928

 Score = 33.1 bits (74), Expect(2) = 7e-04,   Method: Compositional matrix adjust.
 Identities = 35/135 (25%), Positives = 56/135 (41%), Gaps = 15/135 (11%)
 Frame = -1

Query: 92  YDVVKVIGRGAFGEVQLVRHKASQKVYAMKLLSKFEMIK----RSDSAFFWEERDIMAFA 147
           Y   KVIG G+FG            VY  KL+   E++       D  F   E  IM   
Sbjct: 424 YTDAKVIGNGSFGV-----------VYQAKLVDTSELVAIKKVLQDKRFKNRELQIMRKL 278

Query: 148 NSPWVVQLFCAF------QDDRYLYMVMEYMPGGDLVNLMSNYD-----VPEKWAKFYTA 196
               +V+L   F      +D+ +L +V+EY+P   +  +  +Y      +P  + K Y  
Sbjct: 277 EHQNIVKLKFFFYSSGEKKDEVFLNLVLEYVP-ETVYRVARHYSKSKQTIPILYIKLYMY 101

Query: 197 EVVLALDAIHSMGLI 211
           ++  +L  IHS   +
Sbjct: 100 QLFRSLAYIHSQACV 56

 Score = 28.9 bits (63), Expect(2) = 7e-04,   Method: Composition-based stats.
 Identities = 10/15 (66%), Positives = 13/15 (86%)
 Frame = -3

Query: 209 GLIHRDVKPDNMLLD 223
           G+ HRD+KP N+LLD
Sbjct: 65  GVCHRDIKPQNLLLD 21
>07940
          Length = 1336

 Score = 42.7 bits (99), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 31/103 (30%), Positives = 50/103 (48%), Gaps = 2/103 (1%)
 Frame = -3

Query: 194 YTAEVVLALDAIHSMGLIHRDVKPDNMLLDKHGHLKLADFGTCMKMDETGMVHCDTAVGT 253
           Y  +V   ++ + S   IHRD+   N+L+ +   LK+ADFG    + +       T    
Sbjct: 332 YAYQVARGMEYLASKQCIHRDLAARNVLVAEEYVLKIADFGLTRNLQQFDYYRKTTDGRL 153

Query: 254 P-DYISPEVLKSQGGDGYYGRECDWWSVGVFLFEML-VGDTPF 294
           P  +++PE L     D  Y  + D WS GV L+E+  +G  P+
Sbjct: 152 PVKWMAPEALF----DRKYTSKSDVWSYGVLLWEIFTLGGNPY 36
>12672
          Length = 773

 Score = 42.0 bits (97), Expect = 0.002,   Method: Composition-based stats.
 Identities = 25/85 (29%), Positives = 41/85 (48%), Gaps = 3/85 (3%)
 Frame = +3

Query: 209 GLIHRDVKPDNMLLDKHGHLKLADFGTCMKM---DETGMVHCDTAVGTPDYISPEVLKSQ 265
           G +HRD+K  N+LLD     K+ DF T +     +   + +    +GT  Y++PE +   
Sbjct: 51  GHVHRDIKTANILLDSEYTAKVGDFATVVSAPSGEGKTVQNASVVIGTAAYLAPEAIHFD 230

Query: 266 GGDGYYGRECDWWSVGVFLFEMLVG 290
                   + D +S GV L E++ G
Sbjct: 231 -----VSTKLDSYSFGVVLLEVITG 290
>18996
          Length = 491

 Score = 41.2 bits (95), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 28/85 (32%), Positives = 43/85 (50%), Gaps = 2/85 (2%)
 Frame = +2

Query: 211 IHRDVKPDNMLLDKHGHLKLADFGTCMKMDETGMVHCDTAVGTP-DYISPEVLKSQGGDG 269
           IHRD+   N+L+D+   +K++DFG     +  G  +  +    P  + SPE +++     
Sbjct: 2   IHRDLAARNILVDR-SCVKISDFGLAQFANADGYYYGISQRDIPIKWYSPEAIETCKFSS 178

Query: 270 YYGRECDWWSVGVFLFEMLV-GDTP 293
           Y     D WS GV LFEM   G+ P
Sbjct: 179 Y----SDVWSYGVTLFEMFSRGEIP 241
>02638
          Length = 1490

 Score = 41.2 bits (95), Expect = 0.003,   Method: Composition-based stats.
 Identities = 30/106 (28%), Positives = 51/106 (48%), Gaps = 2/106 (1%)
 Frame = +1

Query: 251 VGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLFEMLVGDTPFYADSLVGTYSKIMDHK 310
           +GT  +++PEVL+ +     YGR CD WSVG  + EM     P+ +  +    + I    
Sbjct: 19  LGTIAFMAPEVLRGES----YGRACDVWSVGCVMIEMCTCRPPWNSHDISNHLALIFKIA 186

Query: 311 NSLCFPEDTE-ISKHAKNLICAFL-TDREVRLGRNGVEEIKQHPFF 354
           +S+  P   E +S   ++L+   L  D +    R   +++  HP F
Sbjct: 187 SSVDPPPIPENMSPPVRDLMLRCLEQDSDF---RPSAKDLLMHPLF 315
>32957
          Length = 645

 Score = 40.4 bits (93), Expect = 0.005,   Method: Composition-based stats.
 Identities = 17/40 (42%), Positives = 26/40 (65%)
 Frame = +3

Query: 249 TAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLFEML 288
           T  GT +Y++PEV + +     YG+E DWW +G+ L E+L
Sbjct: 42  TFCGTREYMAPEVHERK----EYGKEVDWWGLGILLHELL 149
>06358
          Length = 1517

 Score = 40.4 bits (93), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 45/171 (26%), Positives = 72/171 (42%), Gaps = 14/171 (8%)
 Frame = +3

Query: 139 EERDIMAFANSPWVVQLFCAFQDDRYLYMVMEYMPGGDLVNLMSNYDVPEKWAKFYTAEV 198
           E R+ +AFA  P    L     D   +  V + +    L      YDV  K       E 
Sbjct: 237 ESRETLAFATEPVFASLANVLGDLSSIXTVPKELQDYQL------YDVEIKHGLLQVTE- 395

Query: 199 VLALDAIHS-MGLIHRDVKPDNMLLDKHGHLKLADFGTCMKMDETGMV---------HCD 248
             AL  +H+   ++HR+V P+ ++L K G  KLA +  C++  +               D
Sbjct: 396 --ALGFLHNDAKMMHRNVCPEAIMLTKLGSWKLAGYEFCVRSSDPQSTDPSYPFYEWRSD 569

Query: 249 TA-VGTP--DYISPE-VLKSQGGDGYYGRECDWWSVGVFLFEMLVGDTPFY 295
            A V  P  D+++PE VL  Q G G      D +S+G+ ++ +     P +
Sbjct: 570 IAPVTQPHLDFMAPEYVLTMQCGTG-----SDMFSLGLLVYSVFAKGKPLF 707
>18401
          Length = 463

 Score = 40.4 bits (93), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 19/46 (41%), Positives = 24/46 (52%)
 Frame = -3

Query: 249 TAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLFEMLVGDTPF 294
           T V T  Y +PEV+   G    +   CD WSVG  +FE+  G T F
Sbjct: 455 TIVSTRHYRAPEVILELG----WSHPCDVWSVGCIMFELYTGYTLF 330
>29590
          Length = 320

 Score = 40.4 bits (93), Expect = 0.005,   Method: Composition-based stats.
 Identities = 22/55 (40%), Positives = 30/55 (54%)
 Frame = +3

Query: 251 VGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLFEMLVGDTPFYADSLVGTYSK 305
           +GTPDY++PEVL  +        + D WS+GV  + ML   +PF     VG  SK
Sbjct: 57  IGTPDYVAPEVLDYEP----LSIQTDMWSLGVLSYVMLTACSPF-----VGITSK 194
>20152
          Length = 445

 Score = 39.3 bits (90), Expect = 0.012,   Method: Composition-based stats.
 Identities = 30/98 (30%), Positives = 45/98 (45%)
 Frame = +1

Query: 259 PEVLKSQGGDGYYGRECDWWSVGVFLFEMLVGDTPFYADSLVGTYSKIMDHKNSLCFPED 318
           PE+L    GD Y     D WS+GV L+ ++VG+ PF   +   T + IMD +  +     
Sbjct: 1   PEILL---GDSYDAPAVDVWSLGVILYMLVVGEAPFQEANDSETLTMIMDCRYQI----P 159

Query: 319 TEISKHAKNLICAFLTDREVRLGRNGVEEIKQHPFFKN 356
             IS   ++LI   L    V   R  +  I  HP+  +
Sbjct: 160 PHISHKCQDLIEKMLQREPV--DRASLPHILAHPWLND 267
>13840
          Length = 446

 Score = 38.9 bits (89), Expect = 0.016,   Method: Compositional matrix adjust.
 Identities = 37/134 (27%), Positives = 59/134 (44%), Gaps = 7/134 (5%)
 Frame = -1

Query: 89  AEDYDVVKVIGRGAFGEVQLVRHKASQKVYAMK-LLSKFEMIKRSDSAFFWEERDIMAFA 147
           +ED   +  IGRG +G V  +RHK +  V A+K + S  E  +R       +   +M   
Sbjct: 398 SEDMQDMGEIGRGNYGTVNKMRHKITSTVMAVKRIRSTVE--EREQKQLLMDLDVVMRSN 225

Query: 148 NSPWVVQLFCAFQDDRYLYMVMEYMPGG-----DLVNLMSNYDVPEKWAKFYTAEVVLAL 202
           N P++VQ + A   +   ++ ME M          V       +PE      T   + AL
Sbjct: 224 NCPFIVQFYGALFKEGDCWICMELMETSLDKFYKFVYGEMQSSIPENILGKITVATLKAL 45

Query: 203 DAI-HSMGLIHRDV 215
           + +   + +IHRDV
Sbjct: 44  NYLKEELRIIHRDV 3
>07291
          Length = 833

 Score = 38.1 bits (87), Expect = 0.024,   Method: Compositional matrix adjust.
 Identities = 22/88 (25%), Positives = 45/88 (51%), Gaps = 3/88 (3%)
 Frame = +1

Query: 210 LIHRDVKPDNMLLDKHGHLKLADFGTCMKMDETGMVHCD--TAVGTPDYISPEVLKSQGG 267
           ++HR++   N ++ + G L+L+D+G    +        D   A     +++PE +     
Sbjct: 112 VVHRNLAARNCIVTEDGRLQLSDYGVTGSLFPQSYYTADDSPARDLVKWMAPETID---- 279

Query: 268 DGYYGRECDWWSVGVFLFEMLV-GDTPF 294
           + ++  + D W+ GV L+E+L  G TP+
Sbjct: 280 NFHFSSKSDVWAFGVVLWELLTRGITPY 363
>18481
          Length = 437

 Score = 37.7 bits (86), Expect = 0.035,   Method: Composition-based stats.
 Identities = 22/49 (44%), Positives = 29/49 (59%), Gaps = 4/49 (8%)
 Frame = -1

Query: 202 LDAIHSMGLIHRDVKPDNML--LDKHGH-LKLADFGTCMKMDET-GMVH 246
           L+ IH    IHRD+KPDN L  L +H H L + DFG   +  +T G +H
Sbjct: 158 LEFIHQKCFIHRDLKPDNFLMGLGRHCHRLYIIDFGLSKRYKDTQGTMH 12
>17300
          Length = 480

 Score = 37.4 bits (85), Expect = 0.046,   Method: Composition-based stats.
 Identities = 26/99 (26%), Positives = 48/99 (48%), Gaps = 4/99 (4%)
 Frame = +1

Query: 201 ALDAIHSMGLIHRDVKPDNMLLDKHGHLKLADFGTCMKM--DETGMVHCDTAVGTP-DYI 257
            +  +  MG +HRD+   N+L+++    K+ADFG   ++  D T   +       P  + 
Sbjct: 10  GMGXLADMGYVHRDLAARNILVNEILVCKVADFGLSREIESDTTEGAYTTKGGKIPVRWT 189

Query: 258 SPEVLKSQGGDGYYGRECDWWSVGVFLFE-MLVGDTPFY 295
           +PE +  +     +    D WS GV ++E M  G+ P++
Sbjct: 190 APEAIAYRK----FTSASDVWSFGVVMWEVMSYGERPYW 294
>33586
          Length = 551

 Score = 37.0 bits (84), Expect = 0.053,   Method: Composition-based stats.
 Identities = 19/49 (38%), Positives = 31/49 (63%), Gaps = 1/49 (2%)
 Frame = +2

Query: 151 WVVQLFCAFQDDRYLYMVMEYMPGGDLVNLMSNYDV-PEKWAKFYTAEV 198
           ++V L  AFQ +  LY+++E++ GGDL   +S   +  E+  KFY AE+
Sbjct: 404 FIVHLHYAFQTEGKLYLILEFLRGGDLFTRLSKEVMFTEEDVKFYLAEL 550
>29360
          Length = 363

 Score = 37.0 bits (84), Expect = 0.055,   Method: Compositional matrix adjust.
 Identities = 22/72 (30%), Positives = 38/72 (52%), Gaps = 2/72 (2%)
 Frame = +3

Query: 153 VQLFCAFQDDRYLYMVMEYMPGG--DLVNLMSNYDVPEKWAKFYTAEVVLALDAIHSMGL 210
           V+ F  FQ   +  +V E +     D +       +P K+ +  T +V+ AL  +  +GL
Sbjct: 144 VRAFECFQHKNHTCLVFEMLEQNLYDFLKQNKFQPLPLKYIRPITQQVLTALRKLKQLGL 323

Query: 211 IHRDVKPDNMLL 222
           IH D+KP+N++L
Sbjct: 324 IHADLKPENIML 359
>11404
          Length = 563

 Score = 37.0 bits (84), Expect = 0.056,   Method: Compositional matrix adjust.
 Identities = 39/156 (25%), Positives = 70/156 (44%), Gaps = 22/156 (14%)
 Frame = +1

Query: 89  AEDYDVVKVIGRGAFGEVQLVRHKASQKVYAMKLLSK--------------FEMIKRSDS 134
           A+ Y++  +IG+G+FG+V         +  A+K++                 EM+ R D+
Sbjct: 136 ADRYEIDSLIGKGSFGQVVKAYDHTDNEQVAIKIIKNKKPFLNQAQIEVKLLEMMNRHDT 315

Query: 135 AFFWEERDIMAFANSPWVVQLFCAFQDDRYLYMVMEYMPGGDLVNLMSN-------YDVP 187
                        N  ++V+L   F    +L +V E +   +L +L+ N        ++ 
Sbjct: 316 ------------DNKYYIVRLKRHFMFRSHLCLVFELL-SYNLYDLLRNTNFRGVSLNLT 456

Query: 188 EKWA-KFYTAEVVLALDAIHSMGLIHRDVKPDNMLL 222
            K+A +  TA + LA      M +IH D+KP+N+LL
Sbjct: 457 RKFAQQLCTALLFLATP---EMSIIHCDLKPENILL 555
>26009
          Length = 886

 Score = 36.6 bits (83), Expect = 0.070,   Method: Composition-based stats.
 Identities = 16/32 (50%), Positives = 24/32 (75%)
 Frame = +3

Query: 191 AKFYTAEVVLALDAIHSMGLIHRDVKPDNMLL 222
           AK    ++V ALD +HS  L+HRD+KP+N+L+
Sbjct: 717 AKSVMKQLVSALDFMHSKQLVHRDIKPENVLI 812

 Score = 36.6 bits (83), Expect = 0.077,   Method: Compositional matrix adjust.
 Identities = 17/36 (47%), Positives = 23/36 (63%)
 Frame = +2

Query: 90  EDYDVVKVIGRGAFGEVQLVRHKASQKVYAMKLLSK 125
           E YDV K +GRG +G+V L R + +    A+KLL K
Sbjct: 416 EHYDVCKELGRGTYGKVVLARCRHTGTQVALKLLPK 523
>31489
          Length = 329

 Score = 36.2 bits (82), Expect = 0.10,   Method: Composition-based stats.
 Identities = 16/64 (25%), Positives = 37/64 (57%)
 Frame = +3

Query: 158 AFQDDRYLYMVMEYMPGGDLVNLMSNYDVPEKWAKFYTAEVVLALDAIHSMGLIHRDVKP 217
           ++ D + +++V + M       + S+  + E+  +++  +++  L  IHS  ++HRD+KP
Sbjct: 72  SYHDFKDIHVVFDLMESDLHRIIYSDQPLTEEHIRYFLYQILRGLKYIHSANVVHRDLKP 251

Query: 218 DNML 221
            N+L
Sbjct: 252 SNLL 263
>01106
          Length = 878

 Score = 35.8 bits (81), Expect = 0.11,   Method: Compositional matrix adjust.
 Identities = 38/147 (25%), Positives = 69/147 (46%), Gaps = 16/147 (10%)
 Frame = +3

Query: 92  YDVVKVIGRGAFGEVQLVRHKASQKVYAMKLL--------SKFEMIKRSDSAFFWEERDI 143
           Y V++ +G G F  V L      ++  A+K++        +  + +K         E D+
Sbjct: 324 YHVIRKLGWGHFSTVWLCWDLTCKRFVALKVVKSAQHYTETALDEVKLLKCV---RESDV 494

Query: 144 MAFANSPWVVQLFCAFQ----DDRYLYMVMEYMPGGDLVNLM--SNY-DVPEKWAKFYTA 196
              A +   VQL   F+    +  ++ MV E + G +L+ L+  SNY  +P    K    
Sbjct: 495 ADPARAK-CVQLLDDFKISGVNGTHVAMVFEVL-GYNLLKLIIRSNYQGIPIHNVKLIIR 668

Query: 197 EVVLALDAIHS-MGLIHRDVKPDNMLL 222
           +V+  L  +H+   +IH D+KP+N+L+
Sbjct: 669 QVLEGLSYMHAKCRIIHTDIKPENILI 749
>21210
          Length = 518

 Score = 35.4 bits (80), Expect = 0.17,   Method: Composition-based stats.
 Identities = 27/110 (24%), Positives = 42/110 (38%), Gaps = 6/110 (5%)
 Frame = +3

Query: 252 GTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLFEMLVGDTPFYADSLVGTYSKIMDHKN 311
           G   Y++PE +  +     Y    D WS+G+ L E+  G  P+        +  I D   
Sbjct: 6   GCRPYMAPERIDPRASSHGYDVRSDVWSLGITLMELATGRFPYR------KWVSIFDQLQ 167

Query: 312 SL------CFPEDTEISKHAKNLICAFLTDREVRLGRNGVEEIKQHPFFK 355
            +      C P D   S    N +   LT  E +  R    ++  HPF +
Sbjct: 168 QVVRGVAPCLPHDGAFSHDFVNFVNKCLTKDEKQ--RPKYNKLLAHPFVR 311
>17516
          Length = 453

 Score = 32.7 bits (73), Expect = 1.1,   Method: Composition-based stats.
 Identities = 16/42 (38%), Positives = 25/42 (59%)
 Frame = -3

Query: 249 TAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLFEMLVG 290
           T  GTP Y++PEVL  +   G Y  + D +S+ + L+E+  G
Sbjct: 442 TLAGTPVYMAPEVLLQK---GQYDMKADVYSLAIILWELWYG 326
>35187
          Length = 593

 Score = 32.0 bits (71), Expect = 2.0,   Method: Composition-based stats.
 Identities = 16/56 (28%), Positives = 23/56 (41%)
 Frame = -3

Query: 1260 GHEFIPTLYHFPTNCEACMKPLWHMFKPPPALECRRCHIKCHKDHMDKKEEIIAPC 1315
            GH F    +H PT C  C   LW +        C  C+   H   M   + +++PC
Sbjct: 318  GHFFTKKTFHKPTYCHHCTDILWGLIG--VGYVCEVCNFVVHDRCM---KTVVSPC 166
>25445
          Length = 460

 Score = 31.2 bits (69), Expect = 3.1,   Method: Composition-based stats.
 Identities = 22/82 (26%), Positives = 35/82 (42%), Gaps = 17/82 (20%)
 Frame = -1

Query: 1261 HEFIPTLYHFPTNCEACMKPLWHMFKPPPALECRRCHIKCHK------------DHMDKK 1308
            H+F    Y  PT C+ C   L+ +      L+C  C + CHK            DH +++
Sbjct: 397  HKFKAHTYGSPTFCDHCGSLLYGLIHQ--GLKCDSCDMNCHKRCEKHVPRLCGMDHTERR 224

Query: 1309 EEI---IAP--CKVYYDISSAK 1325
              I   I+P   K+  ++  AK
Sbjct: 223  GRIYLRISPHGSKLLVNVKEAK 158
>27274
          Length = 396

 Score = 31.2 bits (69), Expect = 3.3,   Method: Composition-based stats.
 Identities = 17/56 (30%), Positives = 29/56 (51%), Gaps = 8/56 (14%)
 Frame = -1

Query: 260 EVLKSQGGDGYYGRECDWWSVGVFLFEMLVGDTPF--------YADSLVGTYSKIM 307
           E+L+ Q     +G   D WS+G+ L E+L G  PF         A +++  Y++I+
Sbjct: 375 ELLRGQ----QHGPTVDMWSLGILLHELLSGHVPFEPERGSRQMARNMMAVYAQII 220
>21800
          Length = 855

 Score = 30.4 bits (67), Expect = 4.7,   Method: Composition-based stats.
 Identities = 25/78 (32%), Positives = 44/78 (56%), Gaps = 8/78 (10%)
 Frame = +2

Query: 153 VQLFCAFQ----DDRYLYMVMEYMPGGDLVNLM--SNYD-VPEKWAKFYTAEVVLALDAI 205
           VQL   F+    +  ++ MV E + G +L+ L+  SNY  +P    K    +V+  L+ +
Sbjct: 506 VQLLDDFKISGVNGTHVCMVFEVL-GYNLLKLIIRSNYQGIPVHNVKLIIRQVLEGLNYL 682

Query: 206 HSM-GLIHRDVKPDNMLL 222
           H+   +IH D+KP+N+L+
Sbjct: 683 HAKCNIIHTDIKPENILI 736
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|154146209|ref|NP_001003918.2| ubiquitin specific
peptidase 7 [Mus musculus]
         (1103 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

01907                                                                 256   5e-68
29736                                                                 142   5e-34
34869                                                                  85   2e-21
11884                                                                  65   1e-10
08419                                                                  50   6e-06
12789                                                                  35   0.14 
03515                                                                  35   0.16 
09373                                                                  31   2.8  
>01907
          Length = 1360

 Score =  256 bits (653), Expect = 5e-68,   Method: Compositional matrix adjust.
 Identities = 124/220 (56%), Positives = 166/220 (75%), Gaps = 3/220 (1%)
 Frame = -3

Query: 887  TDFENRRSFKCIWLNSQFREE-EITLYPDKHGCVRDLLEECKKAVELGDKASGRLRLLEI 945
            +D EN+R FKC W+N + +EE E+ LYPDK+G V DLL E +K VEL +  +G+LRLLEI
Sbjct: 1358 SDLENKRQFKCSWVNGKMKEERELVLYPDKNGRVSDLLSEARKQVELSENGAGKLRLLEI 1179

Query: 946  VSYKIIGVHQEDELLECLSPATSRTFRIEEIPLDQVDIDKENEMLITVAHFHKEVFGTFG 1005
            +SYKI+ V +ED  LE LS   +RTFR+EE+P+D+V +  E+E+LI VAHFHKE++ TFG
Sbjct: 1178 ISYKILSVQREDVQLEQLSVGGTRTFRVEEVPVDEVSLP-EDELLIPVAHFHKEIYQTFG 1002

Query: 1006 IPFLLRIHQGEHFREVMKRIQSLLDIQEKEFEKFKFAIVMMGRHQYINEDEYEVNLKDFE 1065
            IPFLL+I   E F +V +RIQ  +D+ +KEFEK+KFA+++MGR +YI+ED+  V++  F 
Sbjct: 1001 IPFLLKIKNNEPFLKVKERIQKRMDVPDKEFEKYKFALIVMGRLEYISEDDKPVSISHFM 822

Query: 1066 PQ--PGNMSHPRPWLGLDHFNKAPKRSRYTYLEKAIKIHN 1103
            PQ   GN    RPWLG+DH NK  KR+RY+Y EKAIKIHN
Sbjct: 821  PQHLHGNNMQARPWLGIDHVNKTAKRTRYSYQEKAIKIHN 702
>29736
          Length = 481

 Score =  142 bits (359), Expect = 5e-34,   Method: Compositional matrix adjust.
 Identities = 68/134 (50%), Positives = 97/134 (72%), Gaps = 3/134 (2%)
 Frame = +1

Query: 968  SRTFRIEEIPLDQVDIDKENEMLITVAHFHKEVFGTFGIPFLLRIHQGEHFREVMKRIQS 1027
            +RTFR+EEIP +++ +  ++E+L+ VAHF KEV+ TFGIPFLL+I   E F +V +RIQ 
Sbjct: 4    TRTFRVEEIPTEEMSLP-DDEVLVPVAHFSKEVYQTFGIPFLLKIKDNEPFSKVKERIQE 180

Query: 1028 LLDIQEKEFEKFKFAIVMMGRHQYINEDEYEVNLKDFEP---QPGNMSHPRPWLGLDHFN 1084
             +D+ EKEFEKFKFA+VMMG+ +Y+ E++  ++ + F P   Q  N    RPWLG+DH  
Sbjct: 181  RIDVPEKEFEKFKFAVVMMGQQEYLTEEDKPISKRQFTPQNLQGSNSMQTRPWLGIDHVT 360

Query: 1085 KAPKRSRYTYLEKA 1098
            K  KRSR++Y EK+
Sbjct: 361  KPNKRSRHSYQEKS 402
>34869
          Length = 556

 Score = 84.7 bits (208), Expect(2) = 2e-21,   Method: Compositional matrix adjust.
 Identities = 50/106 (47%), Positives = 63/106 (59%), Gaps = 6/106 (5%)
 Frame = +1

Query: 19  SEPEDMEMEAGDT------DDPPRITQNPVINGNVTLSDGHSNAEEDMEDDTSWRSEATF 72
           SE EDME +  D       DDPP       +NG V   +    AE +ME+D   R+EATF
Sbjct: 217 SEHEDMETDQIDGNNHHHGDDPP----GESVNGEVK-EESADIAEAEMEED-DCRAEATF 378

Query: 73  QFTVERFSRLSESVLSPPCFVRNLPWKIMVMPRFYPDRPHQKSVGF 118
           ++TV+  S+L E+ LSP C VRNLPWKIM MPR   +   QKS+GF
Sbjct: 379 RYTVKNISKLKETALSPSCMVRNLPWKIMAMPRNSQNADRQKSLGF 516

 Score = 37.4 bits (85), Expect(2) = 2e-21,   Method: Composition-based stats.
 Identities = 14/15 (93%), Positives = 14/15 (93%)
 Frame = +3

Query: 117 GFFLQCNAESDSTSW 131
           GFFLQCNAESDS SW
Sbjct: 510 GFFLQCNAESDSASW 554
>11884
          Length = 952

 Score = 65.1 bits (157), Expect = 1e-10,   Method: Composition-based stats.
 Identities = 49/172 (28%), Positives = 79/172 (45%), Gaps = 2/172 (1%)
 Frame = +3

Query: 321 IPKLFRGKMVSYIQCKXXXXXXXXXXXXXXIQLSIKGKKNIFESFVDYVAVEQLDGDNKY 380
           I ++F G + S +QC               + L++K    +  +   YV  E LD  N Y
Sbjct: 12  IHQVFGGFLRSQVQCLKCGARSNTFEPFMDLSLNLKDVNTVEAALGKYVKPETLDAANAY 191

Query: 381 DAGE-HGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQ 439
           D  +     +A K      +P VL +QL RF +   T    KIN   +FPE+L + +++ 
Sbjct: 192 DCQKCRKKTQARKRFSLHKIPNVLTIQLNRFGF---TRAAGKINKHIQFPEKLNVRQYMS 362

Query: 440 KTDPKDPANYILHAVLVHSGDN-HGGHYVVYLNPKGDGKWCKFDDDVVSRCT 490
           +    DP  Y L+ VL+HSG + + GHY  Y+    +  W   +D  V + +
Sbjct: 363 RRQ-GDPEYYHLYGVLIHSGHHCNMGHYYCYVRSPAN-SWYIMNDSSVHQVS 512
>08419
          Length = 731

 Score = 49.7 bits (117), Expect = 6e-06,   Method: Compositional matrix adjust.
 Identities = 41/138 (29%), Positives = 61/138 (44%), Gaps = 13/138 (9%)
 Frame = +1

Query: 399 LPPVLHLQLMRFMYDPQTDQNIKINDRFEFP------EQLPLDEFLQKTDPKDPAN---- 448
           LP  L +QLMRF Y+ Q   + K+             + L  D   Q+ D   P      
Sbjct: 136 LPECLIIQLMRFQYNAQQGCSTKLRAPVSIRLKGLNLQDLMCDTVTQREDCVSPGQNSSQ 315

Query: 449 -YILHAVLVHSG--DNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHNYGGHDDD 505
            Y L+ + +H G    H GHY+ Y +   D +W ++DD+ V+    E  IE+     +  
Sbjct: 316 MYDLYGLCLHIGADSTHHGHYISY-SLASDSRWYRYDDEAVT----EVNIEYELTTKE-- 474

Query: 506 LSVRHCTNAYMLVYIRES 523
             VR   NAY+L Y R +
Sbjct: 475 --VRQ--NAYILFYKRAT 516
>12789
          Length = 2095

 Score = 35.4 bits (80), Expect = 0.14,   Method: Compositional matrix adjust.
 Identities = 22/59 (37%), Positives = 30/59 (50%), Gaps = 2/59 (3%)
 Frame = +3

Query: 278 KKLTKSFGWET--LDSFMQHDVQELCRVLLDNVENKMKGTCVEGTIPKLFRGKMVSYIQ 334
           K   ++FGW T  +D    HDV+ L RV  D  + K K TCV   + K F+G  +  I 
Sbjct: 678 KARAEAFGWNTYVVDG---HDVEGLSRVFYDASQVKNKPTCV---LAKTFKGNAIQGIS 836
>03515
          Length = 2030

 Score = 35.0 bits (79), Expect = 0.16,   Method: Compositional matrix adjust.
 Identities = 22/53 (41%), Positives = 32/53 (60%), Gaps = 3/53 (5%)
 Frame = -1

Query: 434  LDEFLQKTDPKD--PANYILHAVLVHSGDNHGGHYVVYL-NPKGDGKWCKFDD 483
            ++E L+  D +D   A Y L+A+  H+G   GGHYV Y  NP  +GKW  ++D
Sbjct: 2018 IEEKLKLYDSEDFTGAQYDLYAMSCHTGIMGGGHYVAYSKNP--NGKWYCYND 1866
>09373
          Length = 418

 Score = 30.8 bits (68), Expect = 2.8,   Method: Composition-based stats.
 Identities = 14/41 (34%), Positives = 22/41 (53%), Gaps = 3/41 (7%)
 Frame = -1

Query: 88  SPPC---FVRNLPWKIMVMPRFYPDRPHQKSVGFFLQCNAE 125
           SP C   F+ ++   + ++P + P+RPHQ  V F   C  E
Sbjct: 193 SPSCCRSFLLDILTLVQILPVYRPERPHQSCVSFQRTCPLE 71
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|7304989|ref|NP_038530.1| C-terminal binding protein 1
[Mus musculus]
         (441 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

05955                                                                 254   6e-68
25533                                                                  88   8e-18
02672                                                                  64   1e-10
12358                                                                  47   1e-05
20523                                                                  31   0.92 
06846                                                                  29   4.7  
>05955
          Length = 1009

 Score =  254 bits (648), Expect = 6e-68,   Method: Compositional matrix adjust.
 Identities = 115/145 (79%), Positives = 132/145 (91%)
 Frame = -1

Query: 12  PLGVRPPIMNGPMHPRPLVALLDGRDCTVEMPILKDVATVAFCDAQSTQEIHEKVLNEAV 71
           P+ +R PI NGPMHPRPLVALLDGRDC+VEMPILKDVATVAFCDAQSTQEIHEKVLNEAV
Sbjct: 814 PMSIRGPIPNGPMHPRPLVALLDGRDCSVEMPILKDVATVAFCDAQSTQEIHEKVLNEAV 635

Query: 72  GALMYHTITLTREDLEKFKALRIIVRIGSGFDNIDIKSAGDLGIAVCNVPAASVEETADS 131
           GALM+HTITLT+EDL+KFK+LR+I+RIGSGFDN+D+K+AG++GIAVCNVP   VEE ADS
Sbjct: 634 GALMWHTITLTKEDLDKFKSLRVIIRIGSGFDNVDVKAAGEMGIAVCNVPGYGVEEVADS 455

Query: 132 TLCHILNLYRRTTWLHQALREGTRV 156
           TLC ILNLYRRT WL   +REG ++
Sbjct: 454 TLCLILNLYRRTYWLANMVREGKKL 380

 Score =  210 bits (534), Expect = 1e-54,   Method: Compositional matrix adjust.
 Identities = 99/136 (72%), Positives = 118/136 (86%)
 Frame = -3

Query: 147 HQALREGTRVQSVEQIREVASGAARIRGETLGIIGLGRVGQAVALRAKAFGFNVLFYDPY 206
           H + RE  ++   EQ+RE A G+ARIRG+TLGI+GLGRVG AVA+RAK FGFNV+FYDPY
Sbjct: 404 HGSRRE--KINGPEQLREAAQGSARIRGDTLGIVGLGRVGTAVAVRAKVFGFNVIFYDPY 231

Query: 207 LSDGIERALGLQRVSTLQDLLFHSDCVTLHCGLNEHNHHLINDFTVKQMRQGAFLVNTAR 266
           L+DGIE++LG+ RV TLQ+LLF SDCV+LHC LNEHNHHLIND+T+KQMR GAFL+NTAR
Sbjct: 230 LADGIEKSLGITRVYTLQELLFQSDCVSLHCTLNEHNHHLINDYTIKQMRPGAFLINTAR 51

Query: 267 GGLVDEKALAQALKEG 282
           GGLVDE ALA ALK+G
Sbjct: 50  GGLVDEHALAVALKDG 3
>25533
          Length = 437

 Score = 87.8 bits (216), Expect = 8e-18,   Method: Composition-based stats.
 Identities = 46/120 (38%), Positives = 73/120 (60%)
 Frame = +2

Query: 172 IRGETLGIIGLGRVGQAVALRAKAFGFNVLFYDPYLSDGIERALGLQRVSTLQDLLFHSD 231
           + G+TL IIGLGR+G+ VALR ++FG   + YDP +   +      + +  L+ +   +D
Sbjct: 74  LNGKTLAIIGLGRIGREVALRMQSFGMTTIGYDPIIGADVAAEFDTEWLP-LEQIWQRAD 250

Query: 232 CVTLHCGLNEHNHHLINDFTVKQMRQGAFLVNTARGGLVDEKALAQALKEGRIRGAALDV 291
            +T+H  L     +LIND    + ++G  +VN ARGG+++E AL +AL+ G+  GA LDV
Sbjct: 251 FITVHTPLIPATTNLINDAVFAKCKKGIRVVNCARGGIIEEAALLRALESGQCGGAGLDV 430
>02672
          Length = 2522

 Score = 63.9 bits (154), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 28/64 (43%), Positives = 37/64 (57%)
 Frame = -2

Query: 293  ESEPFSFSQGPLKDAPNLICTPHAAWYSEQXXXXXXXXXXXXXXXXXXXXXPDSLKNCVN 352
            ESEPFS +  P+KD PNL+ TPH+++YSEQ                     PDSL+NCVN
Sbjct: 2521 ESEPFSLASSPVKDCPNLMITPHSSFYSEQSVSELREMAAGEVRRAILGRIPDSLRNCVN 2342

Query: 353  KDHL 356
            K++ 
Sbjct: 2341 KEYF 2330
>12358
          Length = 598

 Score = 47.4 bits (111), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 25/50 (50%), Positives = 30/50 (60%)
 Frame = -2

Query: 266 RGGLVDEKALAQALKEGRIRGAALDVHESEPFSFSQGPLKDAPNLICTPH 315
           RGG+++   LA ALK G I GA LDV E EP   +  PL   PN + TPH
Sbjct: 549 RGGVINHDHLAVALKTGVIGGAGLDVTEPEPLPPTH-PLVHLPNCVVTPH 403
>20523
          Length = 422

 Score = 31.2 bits (69), Expect = 0.92,   Method: Compositional matrix adjust.
 Identities = 17/39 (43%), Positives = 22/39 (56%), Gaps = 1/39 (2%)
 Frame = -1

Query: 278 ALKEGRIRGAALDVHESE-PFSFSQGPLKDAPNLICTPH 315
           ALK G+  GAA DV+  E P S     L + P ++ TPH
Sbjct: 419 ALKSGKCAGAAFDVYAEEPPKSEVTKALINHPKVVATPH 303
>06846
          Length = 1152

 Score = 28.9 bits (63), Expect = 4.7,   Method: Compositional matrix adjust.
 Identities = 16/42 (38%), Positives = 25/42 (59%), Gaps = 1/42 (2%)
 Frame = +2

Query: 102 FDNIDIKSAGDLGIAVCNVPAASVEETADSTLCH-ILNLYRR 142
           FD+IDI   GDLG  +  +P    E++ DS + + + NL +R
Sbjct: 209 FDDIDILVTGDLGFELSEIP----EQSEDSDVVNRVENLLKR 322
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6679439|ref|NP_032933.1| peptidylprolyl isomerase A
[Mus musculus]
         (164 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

00176                                                                 252   7e-68
05336                                                                 247   1e-66
03374                                                                 189   7e-49
07030                                                                 182   4e-47
07382                                                                 167   2e-42
23478                                                                 164   1e-41
03857                                                                 138   1e-33
15913                                                                 136   4e-33
12506                                                                 127   2e-30
12711                                                                 125   6e-30
11676                                                                 107   2e-24
06379                                                                  80   2e-22
05986                                                                  96   9e-21
14547                                                                  89   9e-19
08983                                                                  79   7e-16
02140                                                                  77   3e-15
23338                                                                  53   5e-08
15093                                                                  42   8e-05
21265                                                                  36   0.007
13072                                                                  33   0.037
>00176
          Length = 1408

 Score =  252 bits (643), Expect = 7e-68,   Method: Compositional matrix adjust.
 Identities = 119/159 (74%), Positives = 134/159 (84%)
 Frame = -1

Query: 6   VFFDITADDEPLGRVSFELFADKVPKTAENFRALSTGEKGFGYKGSSFHRIIPGFMCQGG 65
           V+FD+T      GR+  EL  D VPKTAENFRAL T EKGFG+KGSSFHR+IPGFMCQGG
Sbjct: 892 VYFDMTIGGXDAGRIVMELRTDVVPKTAENFRALCTMEKGFGFKGSSFHRVIPGFMCQGG 713

Query: 66  DFTRHNGTGGRSIYGEKFEDENFILKHTGPGILSMANAGPNTNGSQFFICTAKTEWLDGK 125
           DFT HNGTGG+SIYG KF DENF LKHTGPGILSMANAGP TNGSQFF+CTA+T WLDGK
Sbjct: 712 DFTNHNGTGGKSIYGAKFADENFNLKHTGPGILSMANAGPGTNGSQFFLCTAETSWLDGK 533

Query: 126 HVVFGKVKEGMNIVEAMERFGSRNGKTSKKITISDCGQL 164
           HVVFGKV EGM +V+A+E+ GS++GKTSK + I DCGQL
Sbjct: 532 HVVFGKVAEGMEVVKAIEKVGSQSGKTSKPVVIKDCGQL 416
>05336
          Length = 1406

 Score =  247 bits (631), Expect = 1e-66,   Method: Compositional matrix adjust.
 Identities = 115/161 (71%), Positives = 135/161 (83%)
 Frame = +3

Query: 4   PTVFFDITADDEPLGRVSFELFADKVPKTAENFRALSTGEKGFGYKGSSFHRIIPGFMCQ 63
           P V+FD+TAD + +GR+ FELFAD VPKTAENFR+L TGEKGFG+K S FHR+IP FMCQ
Sbjct: 108 PRVYFDMTADGDEIGRIEFELFADVVPKTAENFRSLCTGEKGFGFKNSIFHRVIPEFMCQ 287

Query: 64  GGDFTRHNGTGGRSIYGEKFEDENFILKHTGPGILSMANAGPNTNGSQFFICTAKTEWLD 123
           GGD TR NGTGG+SIYG KFEDENF +KHT PG+LSMANAGP+TNGSQFFI T  T WLD
Sbjct: 288 GGDITRGNGTGGKSIYGNKFEDENFTMKHTKPGLLSMANAGPDTNGSQFFITTVVTSWLD 467

Query: 124 GKHVVFGKVKEGMNIVEAMERFGSRNGKTSKKITISDCGQL 164
           G HVVFG+V +GM+IV  +E+ GSR G+T KKI I+DCG+L
Sbjct: 468 GCHVVFGEVSKGMDIVTEIEKLGSRGGQTKKKIAIADCGEL 590
>03374
          Length = 852

 Score =  189 bits (479), Expect = 7e-49,   Method: Compositional matrix adjust.
 Identities = 95/164 (57%), Positives = 114/164 (69%), Gaps = 1/164 (0%)
 Frame = +1

Query: 2   VNPTVFFDITADDEPLGRVSFELFADKVPKTAENFRALSTGEKGFGYKGSSFHRIIPGFM 61
           V   VFFDIT   EP GRV   LF   V KT  NF+ L+   +G GYKGS FHRII  FM
Sbjct: 37  VTDKVFFDITIGGEPAGRVEIGLFGKTVEKTVRNFKELAEKPQGEGYKGSKFHRIIKDFM 216

Query: 62  CQGGDFTRHNGTGGRSIYGEKFEDENFILKHTGPGILSMANAGPNTNGSQFFICTAKTEW 121
            QGGDFT+ +GTGGRSIYGE+FEDENF LKH G G LSMANAG +TNGSQFFI T +T W
Sbjct: 217 IQGGDFTKGDGTGGRSIYGERFEDENFKLKHYGAGWLSMANAGKDTNGSQFFITTKQTSW 396

Query: 122 LDGKHVVFGKVKEGMNIVEAMERFGS-RNGKTSKKITISDCGQL 164
           LDG+HVVFGK+  GM++V  +E   +    +  K + I++CG +
Sbjct: 397 LDGRHVVFGKILSGMDVVRKIEASATDARDRPVKDVVIANCGVI 528
>07030
          Length = 2391

 Score =  182 bits (463), Expect = 4e-47,   Method: Compositional matrix adjust.
 Identities = 95/169 (56%), Positives = 114/169 (67%), Gaps = 6/169 (3%)
 Frame = +2

Query: 2   VNPTVFFDITADDEPLGRVSFELFADKVPKTAENFRALSTGEKG-----FGYKGSSFHRI 56
           V   VFFDI    E  GR+   LF D VPKTA+NF++L+ G K        YKGS FHR+
Sbjct: 155 VTDKVFFDIEIGGEKAGRIVIGLFGDIVPKTAKNFKSLAVGFKDKDDNTLTYKGSKFHRV 334

Query: 57  IPGFMCQGGDFTRHNGTGGRSIYGEKFEDENFILKHTGPGILSMANAGPNTNGSQFFICT 116
           I  FM QGGDFTR +GTGG+SIYGEKF DENF L H G G LSMANAG +TNGSQFF+ T
Sbjct: 335 IKDFMIQGGDFTRGDGTGGKSIYGEKFADENFKLNHYGAGWLSMANAGKDTNGSQFFLTT 514

Query: 117 AKTEWLDGKHVVFGKVKEGMNIVEAMERFGSR-NGKTSKKITISDCGQL 164
             T WLDG+HVVFGKV EGM++V  +E   +    K  K + I+D G++
Sbjct: 515 KTTSWLDGRHVVFGKVLEGMSVVRKIESTKTDGRDKPHKDVVIADSGEI 661
>07382
          Length = 1486

 Score =  167 bits (423), Expect = 2e-42,   Method: Compositional matrix adjust.
 Identities = 81/144 (56%), Positives = 97/144 (67%), Gaps = 2/144 (1%)
 Frame = +2

Query: 2   VNPTVFFDITADDEPLGRVSFELFADKVPKTAENFRALSTGEKGFGY--KGSSFHRIIPG 59
           V   V FDI+   EP G +   LF D VPKT  NF AL +G+  FGY  KGS FHR+I  
Sbjct: 128 VTKKVVFDISIAGEPAGSIEIGLFGDVVPKTVNNFVALXSGQNAFGYNYKGSKFHRVISD 307

Query: 60  FMCQGGDFTRHNGTGGRSIYGEKFEDENFILKHTGPGILSMANAGPNTNGSQFFICTAKT 119
           FM QGGDF  +NG+G +SIYG+ F+DE+F +KH G G +SMAN GPNTNG QFFI     
Sbjct: 308 FMIQGGDFVHNNGSGSKSIYGDLFDDEDFSVKHYGSGWISMANRGPNTNGCQFFITLRDC 487

Query: 120 EWLDGKHVVFGKVKEGMNIVEAME 143
            WLDG HVVFGKV +GM +V  +E
Sbjct: 488 PWLDGSHVVFGKVIDGMKVVRKIE 559
>23478
          Length = 909

 Score =  164 bits (415), Expect = 1e-41,   Method: Compositional matrix adjust.
 Identities = 83/170 (48%), Positives = 109/170 (64%), Gaps = 9/170 (5%)
 Frame = +1

Query: 4   PTVFFDITADDEPLGRVSFELFADKVPKTAENFRALSTGEKG--------FGYKGSSFHR 55
           P  FFD++  D+P GR+ FEL++D+ PKT ENFRAL TGEKG          YKG+ FHR
Sbjct: 106 PRCFFDVSIGDQPGGRIVFELYSDECPKTCENFRALCTGEKGTSEKTGAVLHYKGAPFHR 285

Query: 56  IIPGFMCQGGDFTRHNGTGGRSIYGEKFEDENFILKHTGPGILSMANAGPNTNGSQFFIC 115
           ++  FM Q GDFT+ +GTGG SIYG  F DENF  KH    +LSMAN G +TNGSQFFI 
Sbjct: 286 VVKDFMVQCGDFTKGDGTGGESIYGGHFADENFKFKHEKECLLSMANRGKDTNGSQFFIT 465

Query: 116 TAKTEWLDGKHVVFGKVKEGMNIVEAMERFGS-RNGKTSKKITISDCGQL 164
           T     LD  HVVFG V  G  +V+ +E+  +    +   ++ +++CG+L
Sbjct: 466 TNPAPHLDNVHVVFGHVLSGQEVVKKIEQLPTDARSRPEVEVKVANCGEL 615
>03857
          Length = 1696

 Score =  138 bits (347), Expect = 1e-33,   Method: Compositional matrix adjust.
 Identities = 66/109 (60%), Positives = 78/109 (71%)
 Frame = +1

Query: 56  IIPGFMCQGGDFTRHNGTGGRSIYGEKFEDENFILKHTGPGILSMANAGPNTNGSQFFIC 115
           +I  FM QGGDFT HNGTGG SIYG+KF+DE+F  KH  P +LSMANAGPNTNGSQFFI 
Sbjct: 13  VIKDFMIQGGDFTNHNGTGGESIYGDKFDDESFDRKHDCPMLLSMANAGPNTNGSQFFIT 192

Query: 116 TAKTEWLDGKHVVFGKVKEGMNIVEAMERFGSRNGKTSKKITISDCGQL 164
           T  T  LDGKHVVFG+V  G N+V  +E         +K  +I+DCG+L
Sbjct: 193 TVPTPHLDGKHVVFGEVIAGHNVVRELENVDKDGETPTKTCSIADCGEL 339
>15913
          Length = 1796

 Score =  136 bits (343), Expect = 4e-33,   Method: Compositional matrix adjust.
 Identities = 68/119 (57%), Positives = 82/119 (68%), Gaps = 8/119 (6%)
 Frame = -1

Query: 4    PTVFFDITADDEPLGRVSFELFADKVPKTAENFRALSTGEKG--------FGYKGSSFHR 55
            P  FFD++  D+P GR+ FEL++D+ PKT ENFRAL TGEKG          YKG+ FHR
Sbjct: 1742 PRCFFDVSIGDQPGGRIVFELYSDECPKTCENFRALCTGEKGTSEKTGAVLHYKGAPFHR 1563

Query: 56   IIPGFMCQGGDFTRHNGTGGRSIYGEKFEDENFILKHTGPGILSMANAGPNTNGSQFFI 114
            ++  FM Q GDFT+ +GTGG SIYG  F DENF  KH    +LSMAN G +TNGSQFFI
Sbjct: 1562 VVKDFMVQCGDFTKGDGTGGESIYGGHFADENFKFKHEKECLLSMANRGKDTNGSQFFI 1386
>12506
          Length = 1056

 Score =  127 bits (319), Expect = 2e-30,   Method: Compositional matrix adjust.
 Identities = 58/86 (67%), Positives = 67/86 (77%)
 Frame = -1

Query: 3   NPTVFFDITADDEPLGRVSFELFADKVPKTAENFRALSTGEKGFGYKGSSFHRIIPGFMC 62
            P V+ DI   +  +GR+  +L AD VPKTAENFR L T EKG+G+KGSSFHRIIP FMC
Sbjct: 639 QPQVYMDIKIGNRAVGRIIMQLRADVVPKTAENFRCLCTHEKGYGFKGSSFHRIIPQFMC 460

Query: 63  QGGDFTRHNGTGGRSIYGEKFEDENF 88
           QGGDFT HNGTGG+SIYG+KFEDE  
Sbjct: 459 QGGDFTNHNGTGGKSIYGKKFEDEKL 382

 Score =  114 bits (284), Expect = 2e-26,   Method: Compositional matrix adjust.
 Identities = 51/91 (56%), Positives = 67/91 (73%)
 Frame = -2

Query: 74  GGRSIYGEKFEDENFILKHTGPGILSMANAGPNTNGSQFFICTAKTEWLDGKHVVFGKVK 133
            G          +NF L+HT  G LSMAN+GPNTNGSQFF+ T KT+WLDGKHVVFG+V 
Sbjct: 425 AGNPSTARSLRTKNFQLRHTAAGDLSMANSGPNTNGSQFFLTTXKTDWLDGKHVVFGRVI 246

Query: 134 EGMNIVEAMERFGSRNGKTSKKITISDCGQL 164
           EG++IV  ME+ G++ GK + K+TI++CG+L
Sbjct: 245 EGLDIVNKMEKCGTKGGKPTDKVTIANCGEL 153
>12711
          Length = 1926

 Score =  125 bits (315), Expect = 6e-30,   Method: Compositional matrix adjust.
 Identities = 68/127 (53%), Positives = 82/127 (64%), Gaps = 1/127 (0%)
 Frame = -2

Query: 17  LGRVSFELFADKVPKTAENFRALSTGEKGFGYKGSSFHRIIPGFMCQGGDFTRHNGTGGR 76
           +G    EL+    P T  NF  L    +G+ Y G  FHRII  FM QGGD T   G GG 
Sbjct: 413 MGTFVLELYWKHAPNTCRNFAELC--RRGY-YNGIKFHRIIKDFMIQGGDPT-GTGRGGS 246

Query: 77  SIYGEKFEDE-NFILKHTGPGILSMANAGPNTNGSQFFICTAKTEWLDGKHVVFGKVKEG 135
           SIYG+ F DE    LKHTG GILSMAN+GPNTNGSQFFI  A T+WLDGKH +FG++  G
Sbjct: 245 SIYGKNFNDEIADDLKHTGAGILSMANSGPNTNGSQFFITLAPTQWLDGKHSIFGRISSG 66

Query: 136 MNIVEAM 142
           M +++ +
Sbjct: 65  MTVIKRI 45
>11676
          Length = 499

 Score =  107 bits (267), Expect = 2e-24,   Method: Compositional matrix adjust.
 Identities = 57/100 (57%), Positives = 63/100 (63%), Gaps = 6/100 (6%)
 Frame = -3

Query: 2   VNPTVFFDITADDEPLGRVSFELFADKVPKTAENFRALSTGE------KGFGYKGSSFHR 55
           V   V+FDI    E  GR+   LF   VPKTAENF+ L  G+      K   YKGS FHR
Sbjct: 302 VTDKVYFDIEIGGEKAGRIVIGLFGKTVPKTAENFKQLCIGDQKSEDGKELTYKGSQFHR 123

Query: 56  IIPGFMCQGGDFTRHNGTGGRSIYGEKFEDENFILKHTGP 95
           +I  FM QGGDFT  +GTGGRSIYGEKF DENF LKH G 
Sbjct: 122 VIKDFMIQGGDFTNGDGTGGRSIYGEKFADENFKLKHYGA 3
>06379
          Length = 1672

 Score = 80.1 bits (196), Expect(2) = 2e-22,   Method: Compositional matrix adjust.
 Identities = 40/64 (62%), Positives = 48/64 (75%)
 Frame = -2

Query: 49   KGSSFHRIIPGFMCQGGDFTRHNGTGGRSIYGEKFEDENFILKHTGPGILSMANAGPNTN 108
            K ++F  ++     +GGDFT  +GTGGRSIYGEKF DENF LKH G G LSMAN+G +TN
Sbjct: 1053 KAANFTALLKTL*FKGGDFTNGDGTGGRSIYGEKFADENFKLKHYGAGWLSMANSGKDTN 874

Query: 109  GSQF 112
            GSQF
Sbjct: 873  GSQF 862

 Score = 42.0 bits (97), Expect(2) = 2e-22,   Method: Compositional matrix adjust.
 Identities = 20/43 (46%), Positives = 25/43 (58%)
 Frame = -3

Query: 2    VNPTVFFDITADDEPLGRVSFELFADKVPKTAENFRALSTGEK 44
            V   V+FDI    E  GR+   LF   VPKTAENF+ L  G++
Sbjct: 1232 VTDKVYFDIEIGGEKAGRIVIGLFGKTVPKTAENFKQLCIGDQ 1104

 Score = 62.4 bits (150), Expect = 8e-11,   Method: Composition-based stats.
 Identities = 44/143 (30%), Positives = 59/143 (41%), Gaps = 22/143 (15%)
 Frame = -1

Query: 44   KGFGYKGSSFHRIIPGFMCQGGDFTR---------------------HNGTGGRSIYGEK 82
            K   YKGS FHR+I  FM QGG F +                         G  +I+G+ 
Sbjct: 1069 KELTYKGSQFHRVIKDFMIQGGRFHQW*WHWWAEYIRRKVC**ELQAEALWGWLAIHGQL 890

Query: 83   FEDENFILKHTGPGILSMANAGPNTNGSQFFICTAKTEWLDGKHVVFGKVKEGMNIVEAM 142
            ++   ++                        I T KT WLDG+HVVFGKV EGM++V  +
Sbjct: 889  WQRHQWL---------------------SVLITTKKTTWLDGRHVVFGKVLEGMDVVRRI 773

Query: 143  ERFG-SRNGKTSKKITISDCGQL 164
            E    S   K  K   I+D G +
Sbjct: 772  ENMKTSARDKPEKDCVIADSGAI 704
>05986
          Length = 1295

 Score = 95.5 bits (236), Expect = 9e-21,   Method: Compositional matrix adjust.
 Identities = 52/117 (44%), Positives = 74/117 (63%), Gaps = 1/117 (0%)
 Frame = -3

Query: 17   LGRVSFELFADKVPKTAENFRALSTGEKGFGYKGSSFHRIIPGFMCQGGDFTRHNGTGGR 76
            +G +  EL++ + PK+  NF  L    +G+ Y G++FHR++  F+ QGGD T   G GG 
Sbjct: 1224 VGDIDVELWSKEAPKSCRNFIQLCL--EGY-YDGTAFHRVVKEFIVQGGDPT-DTGHGGE 1057

Query: 77   SIYGEKFEDE-NFILKHTGPGILSMANAGPNTNGSQFFICTAKTEWLDGKHVVFGKV 132
            S+YG  F+DE +  L+    G+++MANAGP+ NGSQFF   A T  L  KH +FGKV
Sbjct: 1056 SVYGAPFKDEFHSRLRFVRRGLVAMANAGPHDNGSQFFFTMAATPELQNKHTIFGKV 886
>14547
          Length = 491

 Score = 89.0 bits (219), Expect = 9e-19,   Method: Compositional matrix adjust.
 Identities = 48/101 (47%), Positives = 58/101 (57%), Gaps = 8/101 (7%)
 Frame = -1

Query: 6   VFFDITADDEPLGRVSFELFADKVPKTAENFRALSTGEKG--------FGYKGSSFHRII 57
           V+ DI+  +E  GR+  EL++DK PKT ENFRAL TGEKG          Y  S FHRI+
Sbjct: 305 VYMDISIGEEAAGRLVIELYSDKAPKTCENFRALCTGEKGTSEETDLRLXYLNSLFHRIV 126

Query: 58  PGFMCQGGDFTRHNGTGGRSIYGEKFEDENFILKHTGPGIL 98
                QGGD     G GG SI+G  FEDENF + H   G +
Sbjct: 125 RNGWIQGGDIYHGRGNGGESIFGTVFEDENFAIPHDRRGCV 3
>08983
          Length = 430

 Score = 79.3 bits (194), Expect = 7e-16,   Method: Compositional matrix adjust.
 Identities = 39/54 (72%), Positives = 43/54 (79%), Gaps = 1/54 (1%)
 Frame = +3

Query: 78  IYGEKFEDE-NFILKHTGPGILSMANAGPNTNGSQFFICTAKTEWLDGKHVVFG 130
           IYG+ F DE    LKHTG GILSMAN+GPNTNGSQFFI  A T+WLDGKH +FG
Sbjct: 132 IYGKNFNDEIADDLKHTGAGILSMANSGPNTNGSQFFITLAPTQWLDGKHSIFG 293
>02140
          Length = 1796

 Score = 77.0 bits (188), Expect = 3e-15,   Method: Compositional matrix adjust.
 Identities = 50/152 (32%), Positives = 81/152 (53%), Gaps = 10/152 (6%)
 Frame = +3

Query: 17  LGRVSFELFADKVPKTAENFRALSTGEKGFGYKGSSFHRIIPGFMCQGGDFTRHNGTGGR 76
           +G+++ +L+ ++ P+ +ENF  L    K   Y  S FH +    + Q GD T   G GG 
Sbjct: 108 IGQLTVDLYTEERPRCSENFLKLC---KVKYYNFSLFHSVQENLVAQTGDPTA-TGRGGM 275

Query: 77  SIYGEKF-EDENFI-------LKHTGPGILSMANAGPNTNGSQFFICTAKT-EWLDGKHV 127
           S+YG  + E   +        +KH   G+LSM N G   +GSQFFI   ++ ++LDG+H 
Sbjct: 276 SVYGMVYGEQARYFDMEVSPRIKHKKRGLLSMVNNGAGKHGSQFFITLGESLDYLDGEHT 455

Query: 128 VFGKVKEGMNIVEAM-ERFGSRNGKTSKKITI 158
           VFG+V EG  +++ + E +     +  + I I
Sbjct: 456 VFGEVAEGFEVLDKLNEAYCDEKHRPYRDIRI 551
>23338
          Length = 1062

 Score = 53.1 bits (126), Expect = 5e-08,   Method: Compositional matrix adjust.
 Identities = 25/58 (43%), Positives = 37/58 (63%), Gaps = 2/58 (3%)
 Frame = -1

Query: 106  NTNGSQFFICTAKTEWLDGKHVVFGKVKEGMNIVEAMERFGSRNGKTS--KKITISDC 161
            +TNGSQFFI    + +LDGKHV FGKV +G  +++ + R G  +  T+  + + I DC
Sbjct: 1062 DTNGSQFFITLGPSRFLDGKHVAFGKVLKGFTLLKTINRMGPGDDYTTPRRPVRIVDC 889
>15093
          Length = 537

 Score = 42.4 bits (98), Expect = 8e-05,   Method: Compositional matrix adjust.
 Identities = 22/56 (39%), Positives = 31/56 (55%), Gaps = 1/56 (1%)
 Frame = +3

Query: 107 TNGSQFFICTAKTEWLDGKHVVFGKVKEGMNIVEAMERFG-SRNGKTSKKITISDC 161
           TN SQFF        LDGKH VFG++  G+  ++AME+    +  K  ++I I  C
Sbjct: 3   TNKSQFFFTFRSARHLDGKHAVFGRLVGGIETLDAMEKVEVDKKDKPKEEIKIESC 170
>21265
          Length = 579

 Score = 36.2 bits (82), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 18/45 (40%), Positives = 25/45 (55%)
 Frame = -3

Query: 17  LGRVSFELFADKVPKTAENFRALSTGEKGFGYKGSSFHRIIPGFM 61
           +G +  +LFA + PKT ENF   S   +   +    FHR+I GFM
Sbjct: 130 MGDIQCKLFAKECPKTVENFCVHS---RNSYFNNHVFHRVIKGFM 5
>13072
          Length = 608

 Score = 33.5 bits (75), Expect = 0.037,   Method: Compositional matrix adjust.
 Identities = 20/43 (46%), Positives = 24/43 (55%)
 Frame = -3

Query: 18  GRVSFELFADKVPKTAENFRALSTGEKGFGYKGSSFHRIIPGF 60
           G ++ EL  D VPKT ENF  L     G+ Y G+ FHR I  F
Sbjct: 228 GPLNVELHCDMVPKTCENFIKLCAS--GY-YDGTIFHRSIRNF 109
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|9625037|ref|NP_062512.1| ras homolog gene family,
member G [Mus musculus]
         (191 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

11728                                                                 252   7e-68
19656                                                                 190   3e-49
19006                                                                 174   2e-44
31291                                                                 149   6e-37
17872                                                                 117   2e-27
10708                                                                 100   3e-22
07580                                                                  78   2e-15
01972                                                                  60   4e-14
08428                                                                  72   1e-13
00858                                                                  72   2e-13
17511                                                                  68   3e-12
26083                                                                  67   6e-12
07465                                                                  64   4e-11
14456                                                                  62   2e-10
34468                                                                  62   2e-10
34359                                                                  59   1e-09
13750                                                                  58   3e-09
30760                                                                  57   6e-09
11257                                                                  53   7e-08
13901                                                                  53   9e-08
35581                                                                  52   1e-07
27191                                                                  51   2e-07
09700                                                                  51   4e-07
26536                                                                  50   6e-07
32770                                                                  49   2e-06
33374                                                                  46   7e-06
33794                                                                  45   1e-05
36482                                                                  44   3e-05
33380                                                                  44   4e-05
05468                                                                  44   5e-05
36757                                                                  42   2e-04
00552                                                                  37   0.004
32723                                                                  36   0.007
06994                                                                  33   0.089
18509                                                                  32   0.11 
14775                                                                  32   0.14 
25034                                                                  31   0.29 
10862                                                                  28   1.9  
19046                                                                  28   2.7  
09827                                                                  28   3.2  
08153                                                                  27   4.1  
24619                                                                  27   6.0  
28486                                                                  27   6.4  
>11728
          Length = 635

 Score =  252 bits (643), Expect = 7e-68,   Method: Compositional matrix adjust.
 Identities = 117/165 (70%), Positives = 136/165 (82%)
 Frame = -1

Query: 1   MQSIKCVVVGDGAVGKTCLLICYTTNAFPKEYIPTVFDNYSAQSAVDGRTVNLNLWDTAG 60
           MQ+IKCVVVGDGAVGKTCLLI YTTNAFP EYIPTVFDNYSA   VD + +NL LWDTAG
Sbjct: 497 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDSKPINLGLWDTAG 318

Query: 61  QEEYDRLRTLSYPQTNVFVICFSIASPPSYENVRHKWHPEVCHHCPDVPILLVGTKKDLR 120
           QE+YDRLR LSYPQT+VF+ICFS+ SP S+ENV+ KW+PEV HHCP+ PI+LVGTK DLR
Sbjct: 317 QEDYDRLRPLSYPQTDVFLICFSLISPASFENVKAKWYPEVSHHCPNTPIILVGTKLDLR 138

Query: 121 AQPDTLRRLKEQGQAPITPQQGQALAKQIHAVRYLECSALQQDGV 165
              +T+ +LKE+  APIT  QG A+AK I A +YLECSAL Q G+
Sbjct: 137 EDKETIEKLKEKKLAPITYPQGLAMAKDIGAGKYLECSALTQKGL 3
>19656
          Length = 428

 Score =  190 bits (483), Expect = 3e-49,   Method: Compositional matrix adjust.
 Identities = 86/106 (81%), Positives = 95/106 (89%)
 Frame = +3

Query: 1   MQSIKCVVVGDGAVGKTCLLICYTTNAFPKEYIPTVFDNYSAQSAVDGRTVNLNLWDTAG 60
           MQ+IKCVVVGDGAVGKTCLLI YTTNAFP EYIPTVFDNYSA   VDGR VNL LWDTAG
Sbjct: 105 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGRPVNLGLWDTAG 284

Query: 61  QEEYDRLRTLSYPQTNVFVICFSIASPPSYENVRHKWHPEVCHHCP 106
           QE+YDRLR LSYPQT+VF++CFS+ASP S+EN+R KW+PEV HHCP
Sbjct: 285 QEDYDRLRPLSYPQTDVFLLCFSVASPASFENIRAKWYPEVNHHCP 422
>19006
          Length = 568

 Score =  174 bits (441), Expect = 2e-44,   Method: Compositional matrix adjust.
 Identities = 80/133 (60%), Positives = 98/133 (73%)
 Frame = -2

Query: 5   KCVVVGDGAVGKTCLLICYTTNAFPKEYIPTVFDNYSAQSAVDGRTVNLNLWDTAGQEEY 64
           K V+VGDGA GKTCLLI ++ + FP+ Y+PTVF+NY A   VD + V L LWDTAGQE+Y
Sbjct: 432 KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDSKQVELALWDTAGQEDY 253

Query: 65  DRLRTLSYPQTNVFVICFSIASPPSYENVRHKWHPEVCHHCPDVPILLVGTKKDLRAQPD 124
           DRLR LSYP T+V ++CFSI SP S EN+  KW PEV H CP+VPI+LVG KKDLR   +
Sbjct: 252 DRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVRHFCPNVPIILVGNKKDLRNDEN 73

Query: 125 TLRRLKEQGQAPI 137
           T R L +  Q P+
Sbjct: 72  TKRELMKMKQEPV 34
>31291
          Length = 446

 Score =  149 bits (376), Expect = 6e-37,   Method: Compositional matrix adjust.
 Identities = 72/142 (50%), Positives = 93/142 (65%), Gaps = 3/142 (2%)
 Frame = -1

Query: 53  LNLWDTAGQEEYDRLRTLSYPQTNVFVICFSIASPPSYENVRHKWHPEVCHHCPDVPILL 112
           L LWDTAGQE+YDRLR L+YP T+VF++ FS+ S  S +NV+ KW+PE+ HH P VPI+L
Sbjct: 446 LQLWDTAGQEDYDRLRPLAYPNTDVFMLXFSLMSEASMKNVKVKWYPEIRHHDPHVPIVL 267

Query: 113 VGTKKDLRAQPDTLRRLKEQGQAPITPQQGQALAKQIHAVRYLECSALQQDGVKEVFAEA 172
           VGTK DLR   + +R+L+   Q P++  QG  LAK I A RY ECS+  Q+ +K  F E 
Sbjct: 266 VGTKLDLRQDKEAVRKLRSSRQDPVSSNQGNDLAKAIKAKRYFECSSKTQENLKTAFEET 87

Query: 173 VRAVLNPTPIKRGR---SCILL 191
           VR  LN       R    C+LL
Sbjct: 86  VRVALNMDGQNNKRPKPKCVLL 21
>17872
          Length = 700

 Score =  117 bits (294), Expect = 2e-27,   Method: Compositional matrix adjust.
 Identities = 54/120 (45%), Positives = 80/120 (66%)
 Frame = -1

Query: 61  QEEYDRLRTLSYPQTNVFVICFSIASPPSYENVRHKWHPEVCHHCPDVPILLVGTKKDLR 120
           Q+++D LR L YP+TNVF++CFS+ SP S+ NV  KW PE+ +HCP  P+++VGT+ DLR
Sbjct: 700 QDDFDSLRPLCYPETNVFLLCFSVVSPTSFHNVMEKWVPELRYHCPGAPLVVVGTQSDLR 521

Query: 121 AQPDTLRRLKEQGQAPITPQQGQALAKQIHAVRYLECSALQQDGVKEVFAEAVRAVLNPT 180
                L  L +  + P++ ++   +A Q+ A +Y+ECSAL Q  +KEVF   + A LN T
Sbjct: 520 NDVKVLIELAKYKEKPVSEEEAVKMADQLGA-QYVECSALTQKNLKEVFDTGILASLNWT 344
>10708
          Length = 2775

 Score =  100 bits (250), Expect = 3e-22,   Method: Compositional matrix adjust.
 Identities = 51/118 (43%), Positives = 74/118 (62%), Gaps = 1/118 (0%)
 Frame = -3

Query: 75   TNVFVICFS-IASPPSYENVRHKWHPEVCHHCPDVPILLVGTKKDLRAQPDTLRRLKEQG 133
            T +  +C S + +  ++     KW PEV H CP+VPI+LVG KKDLR   +T R L +  
Sbjct: 2653 TQMSSLCASPLTALTAWRTSLKKWTPEVRHFCPNVPIILVGNKKDLRNDENTKRELMKMK 2474

Query: 134  QAPITPQQGQALAKQIHAVRYLECSALQQDGVKEVFAEAVRAVLNPTPIKRGRSCILL 191
            Q P+   +G+A++++I+A  YLECSA  ++GV+EVF  A RA L     K+G  CI+L
Sbjct: 2473 QEPVRLDEGRAMSEKINAYSYLECSAKTKEGVREVFETATRAALQTKKKKKG-GCIVL 2303

 Score = 70.1 bits (170), Expect = 5e-13,   Method: Compositional matrix adjust.
 Identities = 31/46 (67%), Positives = 36/46 (78%)
 Frame = -2

Query: 51   VNLNLWDTAGQEEYDRLRTLSYPQTNVFVICFSIASPPSYENVRHK 96
            V L LWDTAGQE+YDRLR LSYP T+V ++CFSI SP S EN+  K
Sbjct: 2723 VELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEK 2586
>07580
          Length = 921

 Score = 78.2 bits (191), Expect = 2e-15,   Method: Compositional matrix adjust.
 Identities = 50/171 (29%), Positives = 83/171 (48%), Gaps = 7/171 (4%)
 Frame = +3

Query: 28  FPKEYIPTVFDNYSAQSAVDGRTVNLNLWDTAGQEEYDRLRTLSYPQTNVFVICFSIASP 87
           F ++Y PT+ D+Y  Q  VDG+   L + DTAG E++  +R L       F++ +SI + 
Sbjct: 135 FVEKYDPTIEDSYRKQVEVDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFLLAYSITAQ 314

Query: 88  PSYENVRH-KWHPEVCHHCPDVPILLVGTKKDLRAQPDTLRRLKEQGQAPITPQQGQALA 146
            ++ +++  +          DVP+LLVG K DL            + +  +   QGQ LA
Sbjct: 315 STFNDLQELREQILRVKDTDDVPMLLVGNKCDL------------EDERVVGKDQGQGLA 458

Query: 147 KQIHAVRYLECSALQQDGVKEVFAEAVRAVLNPTPIKRG------RSCILL 191
           +      +LE SA  +  V E+F + VR +   +P + G      +SC +L
Sbjct: 459 RSFSCA-FLETSAKARINVNEIFMDLVRQINKKSPEQSGKRTKSKKSCTVL 608
>01972
          Length = 2359

 Score = 59.7 bits (143), Expect(2) = 4e-14,   Method: Compositional matrix adjust.
 Identities = 28/70 (40%), Positives = 43/70 (61%)
 Frame = +3

Query: 51  VNLNLWDTAGQEEYDRLRTLSYPQTNVFVICFSIASPPSYENVRHKWHPEVCHHCPDVPI 110
           +  N+WDTAGQE++  LR   Y Q    VI F + S  +Y+NV + WH ++   C ++PI
Sbjct: 447 LKFNVWDTAGQEKFGGLRDGYYIQGQCAVIMFDVTSRVTYKNVPN-WHRDLVRVCENIPI 623

Query: 111 LLVGTKKDLR 120
           +L G K D++
Sbjct: 624 VLCGNKVDIK 653

 Score = 34.3 bits (77), Expect(2) = 4e-14,   Method: Compositional matrix adjust.
 Identities = 14/32 (43%), Positives = 19/32 (59%)
 Frame = +1

Query: 3   SIKCVVVGDGAVGKTCLLICYTTNAFPKEYIP 34
           + K V+VGDG VGKT  +  + T  F K  +P
Sbjct: 301 TFKLVLVGDGGVGKTTFVKRHVTGEFEKNMLP 396
>08428
          Length = 1109

 Score = 72.4 bits (176), Expect = 1e-13,   Method: Compositional matrix adjust.
 Identities = 48/176 (27%), Positives = 88/176 (50%), Gaps = 2/176 (1%)
 Frame = -3

Query: 1    MQSIKCVVVGDGAVGKTCLLICYTTNAFPKEYIPTVFDNYSAQS-AVDGRTVNLNLWDTA 59
            M+ +K  ++GD  VGK+ +++ + T ++      T+  ++ ++S  VDG      +WDTA
Sbjct: 1077 MRDVKVCLLGDSGVGKSSIVLRFVTGSYRPSQESTIGASFMSKSLVVDGAGYRFQIWDTA 898

Query: 60   GQEEYDRLRTLSYPQTNVFVICFSIASPPSYENVRHKWHPEV-CHHCPDVPILLVGTKKD 118
            GQE++  L  + Y      VI + +  P ++++V+  W  E+     P++ + + G K D
Sbjct: 897  GQEKFRALAPMYYRGAAAAVIVYDVTRPRTFKSVKS-WIQELRSFGPPNIVLAIAGNKCD 721

Query: 119  LRAQPDTLRRLKEQGQAPITPQQGQALAKQIHAVRYLECSALQQDGVKEVFAEAVR 174
            L    + LR + E        +  Q  A  I A+ + E SA+    V+E+F E  R
Sbjct: 720  L----EELREVVE--------KDAQEYASSISAI-FGETSAMTAVNVEEMFTELAR 592
>00858
          Length = 1658

 Score = 72.0 bits (175), Expect = 2e-13,   Method: Compositional matrix adjust.
 Identities = 48/162 (29%), Positives = 80/162 (49%), Gaps = 1/162 (0%)
 Frame = -2

Query: 16   KTCLLICYTTNAFPKEYIPTVFDNYSAQSAVDGRTVNLNLWDTAGQEEYDRLRTLSYPQT 75
            K+ L I    N F +EY PT  D+   Q  +DG T  L++ DTAGQEE   +R       
Sbjct: 1552 KSALTIQLXQNHFVEEYDPTXEDSXRKQVVIDGETCLLDILDTAGQEEXSAMRDQCMRTG 1373

Query: 76   NVFVICFSIASPPSYENV-RHKWHPEVCHHCPDVPILLVGTKKDLRAQPDTLRRLKEQGQ 134
              F+  F++ +  S+E++ +++   +      +VP++LVG K DL  +            
Sbjct: 1372 EGFLCVFAVXNLKSFEDINQYREQIKRVKDADEVPMVLVGNKVDLPIR------------ 1229

Query: 135  APITPQQGQALAKQIHAVRYLECSALQQDGVKEVFAEAVRAV 176
              +  +QG+ +A+  H + Y+E SA  + GV + F   VR +
Sbjct: 1228 -NVEQRQGKHMAELYH-IPYVETSAKTRQGVDDAFYTLVREI 1109
>17511
          Length = 483

 Score = 67.8 bits (164), Expect = 3e-12,   Method: Compositional matrix adjust.
 Identities = 35/122 (28%), Positives = 60/122 (49%), Gaps = 6/122 (4%)
 Frame = -3

Query: 4   IKCVVVGDGAVGKTCLLICYTTNAFPKEYIPTVFDNY-SAQSAVDGRTVNLNLWDTAGQE 62
           +K +++GD  VGKT L+  Y    F  +Y  T+  ++ + +  VD R V + +WDTAGQE
Sbjct: 364 LKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQIWDTAGQE 185

Query: 63  EYDRLRTLSYPQTNVFVICFSIASPPSYENVRHKWHPEVCHHCP-----DVPILLVGTKK 117
            +  L    Y   +  V+ F +  P ++ ++   W  E           + P +++G K 
Sbjct: 184 RFQSLGVAFYRGADCCVLVFDVTMPNTFRSL-DSWRDEFLIQASPRDPENFPFVVIGNKI 8

Query: 118 DL 119
           DL
Sbjct: 7   DL 2
>26083
          Length = 432

 Score = 66.6 bits (161), Expect = 6e-12,   Method: Compositional matrix adjust.
 Identities = 43/121 (35%), Positives = 66/121 (54%), Gaps = 5/121 (4%)
 Frame = +1

Query: 1   MQSIKCVVVGDGAVGKTCLLICYTTNAFPKEYIPTV-FDNYSAQSAVDGRTVNLNLWDTA 59
           ++  K V +G+ +VGKT L+  +  ++F   Y  T+  D  S    ++ RT+ L LWDTA
Sbjct: 70  LRKFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTIRLQLWDTA 249

Query: 60  GQEEYDRLRTL--SYPQ-TNVFVICFSIASPPSYENVRHKWHPEV-CHHCPDVPILLVGT 115
           GQE   R R+L  SY + ++V V+ + I +  S+     KW  +V      DV I+LVG 
Sbjct: 250 GQE---RFRSLIPSYIRDSSVAVVVYDITNANSFHQT-SKWIDDVRTERGSDVIIMLVGN 417

Query: 116 K 116
           K
Sbjct: 418 K 420
>07465
          Length = 1103

 Score = 63.5 bits (153), Expect = 4e-11,   Method: Compositional matrix adjust.
 Identities = 44/154 (28%), Positives = 69/154 (44%), Gaps = 1/154 (0%)
 Frame = +3

Query: 17  TCLLICYTTNAFPKEYIPTV-FDNYSAQSAVDGRTVNLNLWDTAGQEEYDRLRTLSYPQT 75
           + ++  Y    F K+Y  T+  D    Q  V G  V L LWDTAGQEE+D +    Y   
Sbjct: 240 SSMIQRYCKGIFTKDYKKTIGVDFLERQIEVGGEDVRLMLWDTAGQEEFDAITKAYYRGA 419

Query: 76  NVFVICFSIASPPSYENVRHKWHPEVCHHCPDVPILLVGTKKDLRAQPDTLRRLKEQGQA 135
              V+ FS     S+E +   W  +V     ++ +++V  K DL               A
Sbjct: 420 QACVLAFSTVDRDSFEAL-ETWKRKVEDEVGEIGMVIVQNKIDL------------IDDA 560

Query: 136 PITPQQGQALAKQIHAVRYLECSALQQDGVKEVF 169
            + P++ + LAK++  +R+   S  +   V EVF
Sbjct: 561 VVRPEEAENLAKKLR-LRFYRTSVKENMNVDEVF 659
>14456
          Length = 1867

 Score = 61.6 bits (148), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 42/169 (24%), Positives = 74/169 (43%), Gaps = 6/169 (3%)
 Frame = -1

Query: 12   GAVGKTCLLICYTTNAFPKEYIPTVFDNY-SAQSAVDGRTVNLNLWDTAGQEEYDRLRTL 70
            G VGK+ L+  + +N F  +   T+   + +    VD  T  + +WDTAGQE +  LRT 
Sbjct: 1114 GGVGKSSLMNRFVSNKFDAQSFHTIGVEFLNKDVVVDDETYTMQIWDTAGQERFKSLRTP 935

Query: 71   SYPQTNVFVICFSIASPPSYENVRHKWHPEVCHHCP-----DVPILLVGTKKDLRAQPDT 125
             Y   +  ++ FS+ S  S+ N+   W  E  ++         P +++G K D+  +   
Sbjct: 934  FYRGADCCLLTFSVDSMQSFRNL-SMWRKEFLYYADIQDGVTFPFVVLGNKIDVEGR--- 767

Query: 126  LRRLKEQGQAPITPQQGQALAKQIHAVRYLECSALQQDGVKEVFAEAVR 174
                       +T ++ ++         Y E SA     V++ F  AV+
Sbjct: 766  ----------QVTNEEARSWCTANSNAPYFETSAKDATNVEKAFLAAVQ 650
>34468
          Length = 1502

 Score = 61.6 bits (148), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 39/120 (32%), Positives = 59/120 (49%), Gaps = 4/120 (3%)
 Frame = +1

Query: 4   IKCVVVGDGAVGKTCLLICYTTNAFPKEYIPTVFDNYSAQS-AVDGRTVNLNLWDTAGQE 62
            K +V+GD  VGKTCL   +    FP +   T+  ++  +S  VD   + L LWDTAGQE
Sbjct: 496 FKIIVIGDSNVGKTCLTYRFCLGKFPDKTEATIGVDFREKSIQVDSEHLKLQLWDTAGQE 675

Query: 63  EYDR-LRTLSYPQTNVFVICFSIASPPSYENVRHKWHPEVCHH--CPDVPILLVGTKKDL 119
            + + +    Y   +  V  + +    S+EN+   W  E   H     +P +LVG K D+
Sbjct: 676 RFRKSMVQHYYRNVHAVVFVYDMTKMSSFENMP-AWIEECDRHNLTKYIPRILVGNKCDV 852
>34359
          Length = 1042

 Score = 58.9 bits (141), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 31/92 (33%), Positives = 52/92 (56%), Gaps = 1/92 (1%)
 Frame = +3

Query: 30  KEYIPTV-FDNYSAQSAVDGRTVNLNLWDTAGQEEYDRLRTLSYPQTNVFVICFSIASPP 88
           K+Y+ T+  + +  Q       +  N+WDTAGQE++  LR   Y Q    +I F + S  
Sbjct: 129 KKYVATLGVEVHPLQFNTSRGLLRFNVWDTAGQEKFGGLRDGYYIQGTCAIIMFDVTSRV 308

Query: 89  SYENVRHKWHPEVCHHCPDVPILLVGTKKDLR 120
           +Y+NV + WH ++   C ++PI+L G K D++
Sbjct: 309 TYKNVPN-WHRDLVRVCENIPIVLCGNKVDIK 401
>13750
          Length = 503

 Score = 57.8 bits (138), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 42/158 (26%), Positives = 64/158 (40%), Gaps = 2/158 (1%)
 Frame = -2

Query: 16  KTCLLICYTTNAFPKEYIPT--VFDNYSAQSAVDGRTVNLNLWDTAGQEEYDRLRTLSYP 73
           KTCLL  Y    F    +PT  V  +   +S  D   V   LWDT G E Y  L    + 
Sbjct: 502 KTCLLRRYQKGFFMDRTMPTIAVLCSEFNESRTDPLNVRYTLWDTGGAETYRSLWVSHFR 323

Query: 74  QTNVFVICFSIASPPSYENVRHKWHPEVCHHCPDVPILLVGTKKDLRAQPDTLRRLKEQG 133
              V ++ + +    S+      W   +  + P+  ++ VG+K DL            + 
Sbjct: 322 GAQVALLVYDVTCEWSFLTATTVWRKALMKNIPEAQVIFVGSKTDL------------EE 179

Query: 134 QAPITPQQGQALAKQIHAVRYLECSALQQDGVKEVFAE 171
              I+ ++GQA A Q     + E S++    V  VF E
Sbjct: 178 NRVISTERGQAFATQC-GYTFFETSSVTGKNVDAVFWE 68
>30760
          Length = 596

 Score = 56.6 bits (135), Expect = 6e-09,   Method: Compositional matrix adjust.
 Identities = 50/170 (29%), Positives = 79/170 (46%), Gaps = 15/170 (8%)
 Frame = -1

Query: 5   KCVVVGDGAVGKTCLLICYTTNA--FPKEYIPTVFDNYSAQSAV----------DGRT-V 51
           KC+V GD  VGK+ +   + +++  FPK        NYS  + V          D R  V
Sbjct: 524 KCIVTGDSGVGKSSICQVFHSDSAHFPK--------NYSMTTGVEVLVKLVNIPDSRDQV 369

Query: 52  NLNLWDTAGQEEYDRLRTLSYPQTNVFVICFSIASPPSYENVRHKWHPEVCHHCPD--VP 109
            L L+D+AG+E +    T  + Q +V ++ + +    S+     +W   V    P+  +P
Sbjct: 368 ELYLFDSAGKEIFSENVTKFWDQPSVVMVVYDVTDETSFSGCV-RWLERVRAAKPNTVIP 192

Query: 110 ILLVGTKKDLRAQPDTLRRLKEQGQAPITPQQGQALAKQIHAVRYLECSA 159
            +LV  K DL    D  RR        ++ ++G+ LA Q H + Y ECSA
Sbjct: 191 GVLVANKTDL----DERRR--------VSRKEGKDLA-QSHGLEYFECSA 81
>11257
          Length = 1102

 Score = 53.1 bits (126), Expect = 7e-08,   Method: Compositional matrix adjust.
 Identities = 37/138 (26%), Positives = 58/138 (42%), Gaps = 9/138 (6%)
 Frame = -2

Query: 46   VDGRTVNLNLWDTAGQEEYDRLRTLSYPQTNVFVICFSIASPPSYENVRHKWHPEVCHHC 105
            VDG T  + +WDTAGQE Y  LRT  Y  T+  ++ FS+ +  S +++   W+ E  ++ 
Sbjct: 1041 VDGETFTMQIWDTAGQERYKSLRTPFYRGTDCCLLTFSVDNLKSLQSL-SDWYDEFVNYA 865

Query: 106  -----PDVPILLVGTKKDLR----AQPDTLRRLKEQGQAPITPQQGQALAKQIHAVRYLE 156
                    P +++G K D+     +  D     +  G  P                 Y E
Sbjct: 864  DIQDSASFPFVIIGNKADIEEREVSSEDAYNWCRTHGNLP-----------------YFE 736

Query: 157  CSALQQDGVKEVFAEAVR 174
             SA     V++ F   VR
Sbjct: 735  TSAKDSLNVQQAFLAVVR 682
>13901
          Length = 962

 Score = 52.8 bits (125), Expect = 9e-08,   Method: Compositional matrix adjust.
 Identities = 24/91 (26%), Positives = 47/91 (51%), Gaps = 2/91 (2%)
 Frame = -3

Query: 4   IKCVVVGDGAVGKTCLLICYTTNAFPKEYIPTVFDNYSAQ--SAVDGRTVNLNLWDTAGQ 61
            K +++GD  VGKT  +  Y  ++F ++Y  T+  +++ +     D   + L LWD AGQ
Sbjct: 285 FKVIIIGDPTVGKTSFVQRYVNDSFRRDYKMTIGVDFALKVIRWSDKCNIKLQLWDIAGQ 106

Query: 62  EEYDRLRTLSYPQTNVFVICFSIASPPSYEN 92
           E +  +  + Y   +  ++ F +    +Y+N
Sbjct: 105 ERFTSMTRVYYKDAHACIVMFDLTQKNTYQN 13
>35581
          Length = 364

 Score = 52.4 bits (124), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 29/81 (35%), Positives = 41/81 (50%), Gaps = 2/81 (2%)
 Frame = +2

Query: 4   IKCVVVGDGAVGKTCLLICYTTNAFPKEYIP--TVFDNYSAQSAVDGRTVNLNLWDTAGQ 61
            KCV++GD  VGKTCLL    T+ F    +   T     +  +   G   +++LWDTAGQ
Sbjct: 47  FKCVLLGDAGVGKTCLLNRLATDKFLDSPLTSLTTASLLTTVTLTSGVMASVDLWDTAGQ 226

Query: 62  EEYDRLRTLSYPQTNVFVICF 82
           E Y  L +  Y  T   +I +
Sbjct: 227 ERYRSLTSSYYRDTKAVLIVY 289
>27191
          Length = 443

 Score = 51.2 bits (121), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 29/103 (28%), Positives = 54/103 (52%), Gaps = 2/103 (1%)
 Frame = +1

Query: 16  KTCLLICYTTNAFPKEYIPTVFDNYSAQ-SAVDGRTVNLNLWDTAGQEEYDRLRTLSYPQ 74
           KTCL+  +  + F + Y PTV  +Y  +   V+G  + +++WD +G  EY  +R   Y  
Sbjct: 1   KTCLIKHFCESKFNQGYQPTVGVDYGFKIQTVNGVDMRVHMWDLSGSNEYLDVRNELYTG 180

Query: 75  TNVFVICFSIASPPSYENVRHKWHPEVCHHCPDVPI-LLVGTK 116
           ++   I F +++ PS+E +   W  E+       P+ ++VG +
Sbjct: 181 SDAIFIVFDVSNTPSFEAL-DSWLREINRFATGSPLNVIVGNR 306
>09700
          Length = 1855

 Score = 50.8 bits (120), Expect = 4e-07,   Method: Compositional matrix adjust.
 Identities = 26/67 (38%), Positives = 39/67 (58%)
 Frame = -1

Query: 103  HHCPDVPILLVGTKKDLRAQPDTLRRLKEQGQAPITPQQGQALAKQIHAVRYLECSALQQ 162
            ++ P  P++LVGT+ DLR     L  L +  + P++      LA Q+ A  Y+ECSAL Q
Sbjct: 1831 NNSPRTPLVLVGTQSDLRNDVKVLIELAKYKEKPVSEDDASKLAHQLGA-SYVECSALTQ 1655

Query: 163  DGVKEVF 169
              +KE+F
Sbjct: 1654 KNLKEMF 1634
>26536
          Length = 829

 Score = 50.1 bits (118), Expect = 6e-07,   Method: Compositional matrix adjust.
 Identities = 32/130 (24%), Positives = 58/130 (44%), Gaps = 2/130 (1%)
 Frame = +2

Query: 49  RTVNLNLWDTAGQEEYDRLRTLSYPQTNVFVICFSIASPPSYENVR--HKWHPEVCHHCP 106
           R V+    DTAGQEEY  +R       + F++ +S+    S++      +W         
Sbjct: 122 RRVSWTFLDTAGQEEYSSMREHYTRSGDGFIVVYSVTDVTSFQEAEAVFRWLTRFQDETS 301

Query: 107 DVPILLVGTKKDLRAQPDTLRRLKEQGQAPITPQQGQALAKQIHAVRYLECSALQQDGVK 166
            +  +L G K DL +               +TP++G+ +A ++  + Y E SA   D V 
Sbjct: 302 -IHAVLCGNKTDLTS------------DRKVTPEEGRKMADRL-GMLYFETSAKTGDNVS 439

Query: 167 EVFAEAVRAV 176
           +V+   +R++
Sbjct: 440 QVYHGLLRSI 469

 Score = 38.5 bits (88), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 18/45 (40%), Positives = 26/45 (57%)
 Frame = +2

Query: 5   KCVVVGDGAVGKTCLLICYTTNAFPKEYIPTVFDNYSAQSAVDGR 49
           K V++G G VGK+ L I +T + F   Y PT+ D+Y     V G+
Sbjct: 491 KIVMLGSGGVGKSSLTIRFTQDTFLDVYDPTIEDSYRKMIQVSGQ 625
>32770
          Length = 387

 Score = 48.5 bits (114), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 28/83 (33%), Positives = 46/83 (55%), Gaps = 2/83 (2%)
 Frame = +2

Query: 99  PEVCHHCPDVPILLVGTKKDLR--AQPDTLRRLKEQGQAPITPQQGQALAKQIHAVRYLE 156
           PE+  + P  P +LVGT+ DLR  +QP +        +  +   +G+ LA+++ A+ Y E
Sbjct: 2   PELRDYRPGTPFILVGTQADLRHHSQPAS--------KDMVPAHKGKKLARKVGALGYFE 157

Query: 157 CSALQQDGVKEVFAEAVRAVLNP 179
           CSAL   G+  VF + V   ++P
Sbjct: 158 CSALIGSGLDRVFRQVVTCAVHP 226
>33374
          Length = 489

 Score = 46.2 bits (108), Expect = 7e-06,   Method: Compositional matrix adjust.
 Identities = 31/115 (26%), Positives = 55/115 (47%), Gaps = 1/115 (0%)
 Frame = +1

Query: 46  VDGRTVNLNLWDTAGQEEYDRLRTLSYPQTNVFVICFSIASPPSYENVRHKWHPEVCHHC 105
           +D  TV   +WDTAGQE Y  L  + Y      ++ + I +  ++   +  W  E+    
Sbjct: 160 LDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNQDTFGRAK-TWVKELQRQA 336

Query: 106 -PDVPILLVGTKKDLRAQPDTLRRLKEQGQAPITPQQGQALAKQIHAVRYLECSA 159
            P++ I L G K DL       +R+ E        ++ QA A++ +++ ++E SA
Sbjct: 337 SPNIVIALAGNKADL-----ANKRMVE-------FEEAQAYAEE-NSLLFMETSA 462
>33794
          Length = 779

 Score = 45.4 bits (106), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 33/134 (24%), Positives = 62/134 (46%), Gaps = 1/134 (0%)
 Frame = -1

Query: 46  VDGRTVNLNLWDTAGQEEY-DRLRTLSYPQTNVFVICFSIASPPSYENVRHKWHPEVCHH 104
           ++G+ V L +WDT+GQ  +   +R+ S     + ++ + I +  S++ +  +W  EV  H
Sbjct: 665 LEGKRVKLQIWDTSGQGRFCTIIRSYSRGAQGIILV-YDITNKWSFDGI-DRWLKEVEEH 492

Query: 105 CPDVPILLVGTKKDLRAQPDTLRRLKEQGQAPITPQQGQALAKQIHAVRYLECSALQQDG 164
            P +P +LVG             RL    +  +  +Q +  A + + +   E S L    
Sbjct: 491 APGIPKVLVGN------------RLHLAYKRQVAAKQAETYASR-NNMSCFEISPLCDFN 351

Query: 165 VKEVFAEAVRAVLN 178
           ++E F E  R  L+
Sbjct: 350 IRESFCELARMALH 309
>36482
          Length = 686

 Score = 44.3 bits (103), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 45/172 (26%), Positives = 71/172 (41%), Gaps = 4/172 (2%)
 Frame = +2

Query: 19  LLICYTTNAFPKEYIPTVFDNYSAQSAVDGRTVNLNLWDTAGQEEYDRLRTLSYPQTNVF 78
           L + + T  F  EY PT+   Y   + ++   V L + DTAGQ  Y      +    + F
Sbjct: 2   LTVRFLTRRFIGEYCPTLESVYKYHTVIEDDDVRLEILDTAGQGTYPWKEGYALW-ADCF 178

Query: 79  VICFSIASPPSYEN-VRHKWHPEVCHHCPDVPILLVGTKKDLRAQPDTLRRLKEQGQAPI 137
           V  +SI    SYE  V+ K   E       +  +L   K DL         L ++    +
Sbjct: 179 VFVYSINDRQSYEELVQVKRQVESVRKSTSLTAVLAANKTDL---------LHDR---QV 322

Query: 138 TPQQGQALAKQIHAVRYLECSA---LQQDGVKEVFAEAVRAVLNPTPIKRGR 186
           T ++G+ LA++I   R  E SA    Q + +  +F +  R        + GR
Sbjct: 323 TQKEGEDLAEEI-GCRLYEVSASEGSQMEAITSMFHDLYREFRKHKQQREGR 475
>33380
          Length = 282

 Score = 43.9 bits (102), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 23/72 (31%), Positives = 37/72 (51%), Gaps = 1/72 (1%)
 Frame = +3

Query: 49  RTVNLNLWDTAGQEEYDRLRTLSYPQTNVFVICFSIASPPSYENVRHKWHPEVCHHCPD- 107
           + V L +WDTAGQE Y  + T  Y     F++ + + +  S+ N    W  ++  +  D 
Sbjct: 54  KRVKLQIWDTAGQERYRTITTAYYRGAMGFILMYDVTNEESF-NAVQDWCTQIKTYSWDN 230

Query: 108 VPILLVGTKKDL 119
             ++LVG K DL
Sbjct: 231 AQVVLVGNKCDL 266
>05468
          Length = 1558

 Score = 43.5 bits (101), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 25/99 (25%), Positives = 48/99 (48%), Gaps = 2/99 (2%)
 Frame = -3

Query: 5    KCVVVGDGAVGKTCLLICYTTNAFPKEYIPTVFDNYSAQSA-VDGRT-VNLNLWDTAGQE 62
            K +V+G+   GKT ++  Y    F + Y  T+  +++ +    D  T + L LWD AGQE
Sbjct: 1535 KILVIGELGTGKTSIIKRYVHQFFSQHYRATIGVDFALKVLNWDADTLIRLQLWDIAGQE 1356

Query: 63   EYDRLRTLSYPQTNVFVICFSIASPPSYENVRHKWHPEV 101
             +  +  + Y +     + F +    +++ V  KW  ++
Sbjct: 1355 RFGNMTRVYYKEAVGAFVVFDVTRASTFDAVT-KWKNDL 1242
>36757
          Length = 359

 Score = 42.0 bits (97), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 19/26 (73%), Positives = 22/26 (84%)
 Frame = +2

Query: 152 VRYLECSALQQDGVKEVFAEAVRAVL 177
           V+YLECSAL Q G+K VF EA+RAVL
Sbjct: 2   VKYLECSALTQKGLKTVFDEAIRAVL 79
>00552
          Length = 455

 Score = 37.4 bits (85), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 18/50 (36%), Positives = 30/50 (60%)
 Frame = -3

Query: 55  LWDTAGQEEYDRLRTLSYPQTNVFVICFSIASPPSYENVRHKWHPEVCHH 104
           +WDTAGQE Y  LRT  Y  T+  ++ FS+ +  S +++   W+ E  ++
Sbjct: 147 IWDTAGQERYKSLRTPFYRGTDCCLLTFSVDNLKSLQSL-SDWYDEFVNY 1

 Score = 34.7 bits (78), Expect = 0.025,   Method: Compositional matrix adjust.
 Identities = 16/51 (31%), Positives = 28/51 (54%), Gaps = 1/51 (1%)
 Frame = -1

Query: 4   IKCVVVGDGAVGKTCLLICYTTNAFPKEYIPTVFDNYSAQS-AVDGRTVNL 53
           +K V++GDG VGK+ L+  + +N F  +   T+   +  +   VDG T  +
Sbjct: 443 LKVVLLGDGGVGKSSLMNRFVSNKFDAQSFHTIGVEFLTKDVVVDGETFTM 291
>32723
          Length = 384

 Score = 36.2 bits (82), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 28/109 (25%), Positives = 51/109 (46%), Gaps = 3/109 (2%)
 Frame = +2

Query: 65  DRLRTLS---YPQTNVFVICFSIASPPSYENVRHKWHPEVCHHCPDVPILLVGTKKDLRA 121
           +R R+++   Y   N  ++ + + S  SYE++    H    +    V   LVG K D   
Sbjct: 5   ERFRSITQSYYRSANALILVYDVCSQQSYESLPQWIHEIELYAGTKVLAFLVGNKID--- 175

Query: 122 QPDTLRRLKEQGQAPITPQQGQALAKQIHAVRYLECSALQQDGVKEVFA 170
           Q D         +  I    G+  A++ + +R+LE SA + D V+++F+
Sbjct: 176 QTD---------KREIPTHIGKEFAER-YEMRFLETSAKEADNVEKLFS 292
>06994
          Length = 429

 Score = 32.7 bits (73), Expect = 0.089,   Method: Compositional matrix adjust.
 Identities = 15/31 (48%), Positives = 20/31 (64%)
 Frame = +1

Query: 30  KEYIPTVFDNYSAQSAVDGRTVNLNLWDTAG 60
           K+Y PT+ D+Y  Q  VDG+   L + DTAG
Sbjct: 136 KKYDPTIEDSYRKQVEVDGQQCMLEILDTAG 228
>18509
          Length = 625

 Score = 32.3 bits (72), Expect = 0.11,   Method: Compositional matrix adjust.
 Identities = 25/82 (30%), Positives = 41/82 (50%)
 Frame = -3

Query: 105 CPDVPILLVGTKKDLRAQPDTLRRLKEQGQAPITPQQGQALAKQIHAVRYLECSALQQDG 164
             +VP++LVG K DL      +R +++        +QG+ +A+  H + Y+E SA  + G
Sbjct: 536 ADEVPMVLVGNKVDL-----PIRNVEQ--------RQGKHMAELYH-IPYVETSAKTRQG 399

Query: 165 VKEVFAEAVRAVLNPTPIKRGR 186
           V + F   VR +      K GR
Sbjct: 398 VDDAFYTLVREIRKYKERKDGR 333
>14775
          Length = 380

 Score = 32.3 bits (72), Expect = 0.14,   Method: Compositional matrix adjust.
 Identities = 22/71 (30%), Positives = 30/71 (42%), Gaps = 2/71 (2%)
 Frame = -2

Query: 16  KTCLLICYTTNAFPKEYIPT--VFDNYSAQSAVDGRTVNLNLWDTAGQEEYDRLRTLSYP 73
           KTCLL  Y    F    +PT  V  +   +S  D   V   LWDT G E Y  L    + 
Sbjct: 379 KTCLLRRYQKGFFMDRTMPTIAVLCSEFNESRTDPLNVRYTLWDTGGAETYRSLWVSHFR 200

Query: 74  QTNVFVICFSI 84
              V ++ + +
Sbjct: 199 GAQVALLVYDV 167
>25034
          Length = 527

 Score = 31.2 bits (69), Expect = 0.29,   Method: Compositional matrix adjust.
 Identities = 19/62 (30%), Positives = 31/62 (50%), Gaps = 1/62 (1%)
 Frame = +3

Query: 75  TNVFVICFSIASPPSYENVRHKWHPEV-CHHCPDVPILLVGTKKDLRAQPDTLRRLKEQG 133
           +NVF++  ++   P   N  H+W P+   H  P  P L     K L A+P T+  LK+  
Sbjct: 120 SNVFLMSNALTEYPLCNNCSHRWRPKTHSHQSPGSPSLQPF**KVLSAKPLTIFTLKQTS 299

Query: 134 QA 135
           ++
Sbjct: 300 RS 305
>10862
          Length = 2896

 Score = 28.5 bits (62), Expect = 1.9,   Method: Compositional matrix adjust.
 Identities = 19/76 (25%), Positives = 30/76 (39%), Gaps = 1/76 (1%)
 Frame = -3

Query: 53   LNLWDTAGQEEYDRLRTLSYPQTNVFVICFSIASPPSYENVRHKWHPEVC-HHCPDVPIL 111
             N+WD  GQ++   L    Y  T   +     A     +  R + H  +      D  IL
Sbjct: 2480 FNVWDVGGQDKIRPLWRHYYTGTQGLIFVVDCADRDRIDEARQELHRIINDREMRDAIIL 2301

Query: 112  LVGTKKDLRAQPDTLR 127
            +   K+DL   PD ++
Sbjct: 2300 IFANKQDL---PDAMK 2262
>19046
          Length = 445

 Score = 27.7 bits (60), Expect = 2.7,   Method: Compositional matrix adjust.
 Identities = 24/101 (23%), Positives = 47/101 (46%), Gaps = 2/101 (1%)
 Frame = -2

Query: 61  QEEYDRLRTLSYPQTNVFVICFSIASPPSYENVRHKWHPEVCH--HCPDVPILLVGTKKD 118
           QEE+  +R     + + F++ FS+    S+EN+ + +H ++         P++L   K D
Sbjct: 444 QEEFSAMREQYMRKGDGFLLVFSVTDFRSFENMAN-FHTQILRVKDRDSYPMILCANKVD 268

Query: 119 LRAQPDTLRRLKEQGQAPITPQQGQALAKQIHAVRYLECSA 159
           L              Q  ++ +Q + LA ++  + Y+E SA
Sbjct: 267 L------------VHQRKVSEEQVRDLATRLR-IPYIETSA 184
>09827
          Length = 1201

 Score = 27.7 bits (60), Expect = 3.2,   Method: Compositional matrix adjust.
 Identities = 24/119 (20%), Positives = 46/119 (38%), Gaps = 1/119 (0%)
 Frame = -3

Query: 2    QSIKCVVVGDGAVGKTCLLICYTTNAFPKEYIPTVFDNYSAQSAVDGRTVNLNLWDTAGQ 61
            + ++ ++VG  A GKT +L            IPT+  N      V+ + ++  +WD  GQ
Sbjct: 1118 KDMRILMVGLDAAGKTTILYKLKLGEIVTT-IPTIGFNVET---VEYKNISFTVWDVGGQ 951

Query: 62   EEYDRLRTLSYPQTNVFVICFSIASPPSYENVRHKWHPEVCH-HCPDVPILLVGTKKDL 119
            ++   L    +  T   +           +  R +    +      D  +L+   K+DL
Sbjct: 950  DKIRPLWRHYFQNTQGLIFVVDSNDKERVQEAREELTRMLNEDELRDAVLLVFANKQDL 774
>08153
          Length = 1703

 Score = 27.3 bits (59), Expect = 4.1,   Method: Compositional matrix adjust.
 Identities = 19/69 (27%), Positives = 33/69 (47%)
 Frame = +1

Query: 2   QSIKCVVVGDGAVGKTCLLICYTTNAFPKEYIPTVFDNYSAQSAVDGRTVNLNLWDTAGQ 61
           + ++ ++VG  A GKT +L            IPT+  N      V+ + ++  +WD  GQ
Sbjct: 79  KEVRILMVGLDAAGKTTILYKLKLGEIVTT-IPTIGFNVET---VEYKNISFTVWDVGGQ 246

Query: 62  EEYDRLRTL 70
              D++R L
Sbjct: 247 ---DKIRPL 264
>24619
          Length = 509

 Score = 26.6 bits (57), Expect = 6.0,   Method: Compositional matrix adjust.
 Identities = 24/101 (23%), Positives = 47/101 (46%), Gaps = 2/101 (1%)
 Frame = -2

Query: 61  QEEYDRLRTLSYPQTNVFVICFSIASPPSYENVRHKWHPEVCH--HCPDVPILLVGTKKD 118
           QEE+  +R     + + F++ FS+    S+EN+ + +H ++         P++L   K D
Sbjct: 508 QEEFSAMREQYMRKGDGFLLVFSVIDYQSFENMVN-FHTQILRVKDRDTYPMILCANKVD 332

Query: 119 LRAQPDTLRRLKEQGQAPITPQQGQALAKQIHAVRYLECSA 159
           L              Q  ++ +Q + LA ++  + Y+E SA
Sbjct: 331 L------------VHQRKVSEEQVRDLATRLR-IPYIETSA 248
>28486
          Length = 771

 Score = 26.6 bits (57), Expect = 6.4,   Method: Compositional matrix adjust.
 Identities = 9/24 (37%), Positives = 12/24 (50%)
 Frame = +2

Query: 95  HKWHPEVCHHCPDVPILLVGTKKD 118
           HKW P VC +CP     + G +  
Sbjct: 683 HKWRPTVCSYCPSQTPWISGVRSQ 754
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|11140825|ref|NP_068561.1| trafficking protein
particle complex 4 [Mus musculus]
         (219 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

18428                                                                 252   8e-68
13037                                                                  40   7e-04
18767                                                                  29   1.7  
03234                                                                  27   8.1  
>18428
          Length = 705

 Score =  252 bits (644), Expect = 8e-68,   Method: Compositional matrix adjust.
 Identities = 114/170 (67%), Positives = 144/170 (84%)
 Frame = -1

Query: 1   MAIFSVYVVNKAGGLIYQWDSYSPRAEAEKTFSYPLDLLLKLHDERVLVAFGQRDGIRVG 60
           MAIFSVY+VNKAGGLIYQ D  + R E EKTFSYPL+L+LK+ D++++VAFG+RDGI+VG
Sbjct: 510 MAIFSVYIVNKAGGLIYQHDHNASRPEVEKTFSYPLELVLKIFDDKIVVAFGERDGIKVG 331

Query: 61  HAVLAINGMDVNGKYTADGKEVLEYLGNPANYPVSIRFGRPRLTSNEKLMLASMFHSLFA 120
           H VL+ING+   G++  DG+++LE L    NYP+SI+FGRP+LT+NEK+MLASMFHSLFA
Sbjct: 330 HTVLSINGVAAEGRFLKDGRDILETLAMEENYPISIKFGRPKLTTNEKIMLASMFHSLFA 151

Query: 121 IGSQLSPEQGSSGIEMLETDTFKLHCFQTLTGIKFVVLADPRQAGIDSLL 170
           IG QLSPE  SSGI++LET+TFKLHC QT+TGIKFVV+ DP+Q  +D LL
Sbjct: 150 IGCQLSPEPRSSGIQVLETETFKLHCEQTMTGIKFVVITDPKQMAVDGLL 1
>13037
          Length = 473

 Score = 40.0 bits (92), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 19/56 (33%), Positives = 33/56 (58%), Gaps = 1/56 (1%)
 Frame = +2

Query: 146 CFQTLTGIKFVVLADPR-QAGIDSLLRKIYEIYSDFALKNPFYSLEMPIRCELFDQ 200
            F T   ++F++L D + + GI +   ++YE Y  FA+ NPFY +  PI+   F++
Sbjct: 263 AFVTAGRMRFLILHDAKNEDGIKNFFTEVYETYIKFAM-NPFYEINTPIKSSAFEK 427
>18767
          Length = 467

 Score = 28.9 bits (63), Expect = 1.7,   Method: Compositional matrix adjust.
 Identities = 19/66 (28%), Positives = 34/66 (51%), Gaps = 3/66 (4%)
 Frame = -3

Query: 87  GNPANYPVSIRFGRPRLTSNEKLMLASMFHSLFAIGS---QLSPEQGSSGIEMLETDTFK 143
           GN   Y    R  +P ++ +E+  L  M+  +F+I S   ++SP+    G    +T  +K
Sbjct: 198 GNCLYYAEWNRKNQPGISKDEEFKL--MYGMIFSIKSFINRISPKDVQDGFLNFKTSKYK 25

Query: 144 LHCFQT 149
           LH ++T
Sbjct: 24  LHFYET 7
>03234
          Length = 963

 Score = 26.6 bits (57), Expect = 8.1,   Method: Compositional matrix adjust.
 Identities = 18/55 (32%), Positives = 25/55 (45%), Gaps = 2/55 (3%)
 Frame = -3

Query: 98  FGRPRLTSNEKLMLASMFHSLFAIGSQLSPEQG--SSGIEMLETDTFKLHCFQTL 150
           FGR RL +N +L+           G  L    G  S  ++M E D F+LH   T+
Sbjct: 187 FGRKRLVNNXRLV----------AGCSLKRGSGPWSHEVDMEEGDLFRLHDVHTI 53
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|46048490|ref|NP_032025.2| flap structure specific
endonuclease 1 [Mus musculus]
         (380 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

15265                                                                 253   8e-68
13856                                                                 201   4e-52
15033                                                                  49   3e-06
04762                                                                  30   1.8  
27894                                                                  28   8.9  
>15265
          Length = 767

 Score =  253 bits (647), Expect = 8e-68,   Method: Compositional matrix adjust.
 Identities = 114/201 (56%), Positives = 154/201 (76%)
 Frame = +1

Query: 144 LLSLMGIPYLDXXXXXXXXXXXXXXXXXXXXXXTEDMDCLTFGSPVLMRHLTASEAKKLP 203
           LL LMG+PY++                      TEDMD LTFGS VL+RHLT SEA+K+P
Sbjct: 7   LLKLMGVPYVEAPCEAEAQCAALVKAGKVYATGTEDMDALTFGSKVLLRHLTFSEARKMP 186

Query: 204 IQEFHLSRVLQELGLNQEQFVDLCILLGSDYCESIRGIGPKRAVDLIQKHKSIEEIVRRL 263
           I+EF+L ++L ++  + ++F+DLCILLG DYC+SIRGIGPKRAV+LI++HK+IE I+  L
Sbjct: 187 IKEFYLGQILDDMNFSMDEFIDLCILLGCDYCDSIRGIGPKRAVELIKQHKNIETILEHL 366

Query: 264 DPSKYPVPENWLHKEAQQLFLEPEVLDPESVELKWSEPNEEELVKFMCGEKQFSEERIRS 323
           D  KY VPE+W++KEA++LF EP+V DPE+++LKW++P+EE L+ FM  +K FSE+RIR+
Sbjct: 367 DQKKYTVPEDWMYKEARRLFQEPDVTDPETLDLKWTDPDEEGLIDFMVTQKSFSEDRIRN 546

Query: 324 GVKRLSKSRQGSTQGRLDDFF 344
           G+K+L KSRQGSTQGRLD FF
Sbjct: 547 GIKKLQKSRQGSTQGRLDSFF 609
>13856
          Length = 487

 Score =  201 bits (511), Expect = 4e-52,   Method: Compositional matrix adjust.
 Identities = 94/137 (68%), Positives = 109/137 (79%)
 Frame = +3

Query: 1   MGIHGLAKLIADVAPSAIRENDIKSYFGRKVAIDASMSIYQFLIAVRQGGDVLQNEEGET 60
           MGIHGL+K++ D APS+++EN+IK+YFGRKVAIDASMSIYQFLIAVRQ G  L NEEGET
Sbjct: 57  MGIHGLSKVLGDYAPSSLKENEIKNYFGRKVAIDASMSIYQFLIAVRQDGSQLTNEEGET 236

Query: 61  TSHLMGMFYRTIRMMENGIKPVYVFDGKPPQLKSGELAKRSXXXXXXXXXXXXXXXXGME 120
           TSH+MGMFYRTIRM+ENGIKPVYVFDGKPP +KSGELAKR                 G E
Sbjct: 237 TSHIMGMFYRTIRMLENGIKPVYVFDGKPPDMKSGELAKRKEMREAAQKELEKAEEAGDE 416

Query: 121 EEVEKFTKRLVKVTKQH 137
           E +++F +RLVKVTKQ 
Sbjct: 417 ENIDRFNRRLVKVTKQQ 467
>15033
          Length = 1696

 Score = 49.3 bits (116), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 32/105 (30%), Positives = 58/105 (55%), Gaps = 5/105 (4%)
 Frame = -1

Query: 1    MGIHGLAKLI----ADVAPSAIRENDIKSYFGRKVAIDASMSIYQFLIAVR-QGGDVLQN 55
            MG+ GL +L+      V+P+++         G+ +A+D S+ ++Q +  +R + G+ L N
Sbjct: 1411 MGVQGLWQLLHPAGKPVSPASLE--------GKVLAVDISIWLHQTMKGMRDKDGNPLPN 1256

Query: 56   EEGETTSHLMGMFYRTIRMMENGIKPVYVFDGKPPQLKSGELAKR 100
                  +HL G+F R  +++   I+PV++FDG  P LK   +A R
Sbjct: 1255 ------AHLQGLFSRVCKLLFYRIRPVFIFDGGVPLLKKQTVAIR 1139
>04762
          Length = 916

 Score = 30.0 bits (66), Expect = 1.8,   Method: Compositional matrix adjust.
 Identities = 14/39 (35%), Positives = 21/39 (53%)
 Frame = +1

Query: 8   KLIADVAPSAIRENDIKSYFGRKVAIDASMSIYQFLIAV 46
           K+   + PS IR   +KSYFGR     +S   Y F++ +
Sbjct: 106 KMCFGIIPSLIRIRTLKSYFGRFCIKISSKYFYLFVLII 222
>27894
          Length = 535

 Score = 27.7 bits (60), Expect = 8.9,   Method: Compositional matrix adjust.
 Identities = 14/49 (28%), Positives = 25/49 (51%)
 Frame = -1

Query: 228 ILLGSDYCESIRGIGPKRAVDLIQKHKSIEEIVRRLDPSKYPVPENWLH 276
           +LL SDY   +  +   +   +   H  I++ +   +PS+YP P N+ H
Sbjct: 241 LLLASDYAGCLTSL--MKFPQVADAHYFIDKALWLREPSQYPRPPNYCH 101
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|60218875|ref|NP_036124.2| ATP-binding cassette,
sub-family D, member 2 [Mus musculus]
         (741 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

12308                                                                 254   1e-67
19618                                                                 165   5e-41
19777                                                                 155   5e-38
05764                                                                  56   6e-08
01623                                                                  48   2e-05
02301                                                                  47   2e-05
30281                                                                  44   2e-04
01142                                                                  44   3e-04
38795                                                                  33   0.39 
>12308
          Length = 698

 Score =  254 bits (648), Expect = 1e-67,   Method: Compositional matrix adjust.
 Identities = 124/239 (51%), Positives = 170/239 (71%), Gaps = 3/239 (1%)
 Frame = -3

Query: 422 TARVYNMFWVFDEVKRGIYKRTVTQEPENHSKRGGNLELPLSDTLAIK---GTVIDVDHG 478
           TARV ++  V +++  G Y+RT+     ++  RG   E     ++ +K   G +I  DH 
Sbjct: 696 TARVTDLIKVLEDLNNGRYERTMVT---SNGPRGDGAE----SSMKLKPGNGQLIFKDHV 538

Query: 479 IICENVPIITPAGEVVASRLNFKVEEGMHLLITGPNGCGKSSLFRILSGLWPVYEGVLYK 538
           I  + VP++TP G+V+   L+F+V+ GM++L+ GPNGCGKSSLFRIL  LWP++ G L K
Sbjct: 537 IKFDKVPLVTPNGDVLIPELSFEVKAGMNVLVCGPNGCGKSSLFRILGELWPLFGGSLTK 358

Query: 539 PPPQHMFYIPQRPYMSLGSLRDQVIYPDSADDMREKGYTDQDLERILHSVHLYHIVQREG 598
           P    +FYIPQRPYM++G+LRDQV YPDS ++   KG  D++L  IL  V L +++QREG
Sbjct: 357 PEKGKLFYIPQRPYMTVGTLRDQVTYPDSHEEQLRKGTRDEELADILGKVQLDYVLQREG 178

Query: 599 GWDAVMDWKDVLSGGEKQRMGMARMFYHKPKYALLDECTSAVSIDVEGKIFQAAIGAGI 657
           GWDAV DW DVLSGGEKQR+ MAR+FYHKP++A+LDECTSAVS+DVEG ++Q +   GI
Sbjct: 177 GWDAVQDWMDVLSGGEKQRIAMARLFYHKPQFAILDECTSAVSVDVEGFMYQYSREVGI 1
>19618
          Length = 974

 Score =  165 bits (418), Expect = 5e-41,   Method: Compositional matrix adjust.
 Identities = 81/152 (53%), Positives = 105/152 (69%)
 Frame = +2

Query: 539 PPPQHMFYIPQRPYMSLGSLRDQVIYPDSADDMREKGYTDQDLERILHSVHLYHIVQREG 598
           PPP  + Y       SL S   Q+IYP + DDMR  G +D+DL   L  V L ++ QRE 
Sbjct: 8   PPPTRLTY-------SL-SYNLQIIYPHTRDDMRRLGKSDEDLLHFLDIVQLTYLEQREH 163

Query: 599 GWDAVMDWKDVLSGGEKQRMGMARMFYHKPKYALLDECTSAVSIDVEGKIFQAAIGAGIS 658
           G DA+ DW DVLSGGEKQR+ MAR+FYHKP++A+LDECTSAVS+DVEGK++      GI+
Sbjct: 164 GLDAIEDWIDVLSGGEKQRIAMARLFYHKPQFAILDECTSAVSVDVEGKMYSYCREVGIT 343

Query: 659 LLSITHRPSLWKYHTHLLQFDGEGGWRFEQLD 690
           L +++HR SLW +H + LQFDG G + FE +D
Sbjct: 344 LFTVSHRKSLWVHHDYYLQFDGRGSYEFEAID 439
>19777
          Length = 671

 Score =  155 bits (392), Expect = 5e-38,   Method: Compositional matrix adjust.
 Identities = 80/200 (40%), Positives = 117/200 (58%), Gaps = 5/200 (2%)
 Frame = -1

Query: 490 AGEVVASRLNFKVEEGMHLLITGPNGCGKSSLFRILSGLWPVYEGV---LYKPPPQHMFY 546
           +  V+   L+ K+  G  +L+TG +GCGK+SL R+++GLW    G    + +  P  + Y
Sbjct: 602 SSHVLCRDLSLKLHSGTSILVTGDSGCGKTSLLRVIAGLWKSSTGYVDRIVEQIPSELLY 423

Query: 547 IPQRPYMSLGSLRDQVIYPDSADDMREKGYTDQDLERILHSVHLYHIVQREGGWDAVMDW 606
           +PQ+PY++ GSLRDQ+++P +  D+      D  + R L    L  +++R GG D  MDW
Sbjct: 422 LPQKPYLTTGSLRDQILFPSTEADVVPD---DDKMYRYLSLAGLNQLLERLGGLDVNMDW 252

Query: 607 K--DVLSGGEKQRMGMARMFYHKPKYALLDECTSAVSIDVEGKIFQAAIGAGISLLSITH 664
              D  S GE QR+   R F+HKP++ALLDE TS VS ++EG ++       I+LLSI H
Sbjct: 251 NWYDEXSPGEMQRLSFVRXFFHKPRFALLDEATSQVSQEMEGTLYLQCQKLHITLLSIGH 72

Query: 665 RPSLWKYHTHLLQFDGEGGW 684
           R S+  YH   L F G G W
Sbjct: 71  RDSIRPYHPLSLHFHGSGSW 12
>05764
          Length = 1395

 Score = 55.8 bits (133), Expect = 6e-08,   Method: Compositional matrix adjust.
 Identities = 60/225 (26%), Positives = 94/225 (41%), Gaps = 18/225 (8%)
 Frame = -2

Query: 461  PLSDTLAIKGTVIDVDHGIICENVPIITPA-GEV-VASRLNFKVEEGMHLLITGPNGCGK 518
            P  D  +  G   D    I  E V    P   E+ V   ++ ++  G    + G +GCGK
Sbjct: 1187 PSIDNCSTTGIRKDAKGNIKVEKVEFCYPTRPEIQVLKGISLEISAGQTAALVGISGCGK 1008

Query: 519  SSLFRILSGLWPVYEGVLYKPPPQHMFY-----------IPQRPYMSLGSLRDQVIYPDS 567
            S++  +L   +   +G L         Y           + Q P +   S+RD + Y   
Sbjct: 1007 STIISLLQRYYDPSKGRLLVDGTDVRDYNITALRSLLSVVSQEPILFDCSIRDNIQYGLE 828

Query: 568  ADDMREKGYTDQDLERILHSVHLYH-IVQREGGWDAVMDWKDV-LSGGEKQRMGMARMFY 625
            +D          D+     + +++  I     G+D  +  K   LSGG+KQR+ +AR   
Sbjct: 827  SD------VPMPDIIAACKTANIHEFIASLPQGYDTQVGGKGTQLSGGQKQRVAIARALV 666

Query: 626  HKPKYALLDECTSAVSIDVEGKIFQAAIG---AGISLLSITHRPS 667
              P   LLDE TSA+  + E K+ QAA+     G + + I HR S
Sbjct: 665  RNPIILLLDEATSALDTESE-KLVQAALDNAREGRTCIVIAHRLS 534
>01623
          Length = 1414

 Score = 47.8 bits (112), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 46/192 (23%), Positives = 82/192 (42%), Gaps = 14/192 (7%)
 Frame = +3

Query: 498 LNFKVEEGMHLLITGPNGCGKSSLFRILSGLWPVYEG--------VLYKPPP---QHMFY 546
            N +   G    + GP+G GKS++  +L   +    G        +    P     H+  
Sbjct: 90  FNLQARAGQVTAVVGPSGSGKSTVCGLLLRYYDPNAGQVMLDGQNIAELDPTWLRSHIGT 269

Query: 547 IPQRPYMSLGSLRDQVIYPDSADDMREKGYTDQDLERILHSVHLYHIVQREGGWDAVMDW 606
           + Q P +   S+ + + Y     D    G   +D  R  ++ +         G D ++  
Sbjct: 270 VSQEPILFSCSVAENIAYGAVNPDAVTLGQI-EDAARKANAFNFVSTFPL--GLDTMVGE 440

Query: 607 KDV-LSGGEKQRMGMARMFYHKPKYALLDECTSAVSIDVEGKIFQA--AIGAGISLLSIT 663
           + + LSGG++QR+ +AR     P+  LLDE TSA+  + E  +  A   +  G ++++I 
Sbjct: 441 RGMMLSGGQRQRIAIARAILKNPEILLLDEATSALDAESEYLVQDALEKLMGGRTVITIA 620

Query: 664 HRPSLWKYHTHL 675
           HR S  K    +
Sbjct: 621 HRLSTIKTANQI 656
>02301
          Length = 1098

 Score = 47.4 bits (111), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 38/128 (29%), Positives = 63/128 (49%), Gaps = 6/128 (4%)
 Frame = -2

Query: 544 MFYIPQRPYMSLGSLRDQVIY-PDSADDMREKGYTDQDLERILHSVHLYHIVQR-EGGWD 601
           M  + Q P +   S++D + Y P+         Y D D+       + +  ++    G+D
Sbjct: 869 MALVGQEPVLFSRSIKDNIGYGPEQ--------YNDSDIVTAAMKANAHDFIRALPRGYD 714

Query: 602 -AVMDWKDVLSGGEKQRMGMARMFYHKPKYALLDECTSAVSIDVEGKIFQAAIGA---GI 657
            +V +   +LSGG+KQR+ +AR    +P   LLDE TSA+    E  + Q+AI     G 
Sbjct: 713 TSVGERGLLLSGGQKQRLAIARALVRQPAILLLDEATSALDTQSE-SLVQSAINECTRGR 537

Query: 658 SLLSITHR 665
           +++ I HR
Sbjct: 536 TVVIIAHR 513
>30281
          Length = 821

 Score = 44.3 bits (103), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 37/126 (29%), Positives = 59/126 (46%), Gaps = 7/126 (5%)
 Frame = -2

Query: 546 YIPQRPYMSLGSLRDQVIYPDSADDMREKGYTDQ-DLERILHSVHLYHIVQREGGWDAVM 604
           Y+PQ+ ++   ++RD +++       + K   +Q +LER         +    GG    +
Sbjct: 808 YVPQQAWIQNATVRDNILFGSPYIRSKYKAILEQCELER--------DVAMLPGGDLTQI 653

Query: 605 DWKDV-LSGGEKQRMGMARMFYHKPKYALLDECTSAVSIDVEGKIFQAAIGA-----GIS 658
             K + LSGG+KQR+ +AR  Y      LLD+  SAV   V   IF   IG      G +
Sbjct: 652 GEKGINLSGGQKQRVSVARAVYSDSDVYLLDDPLSAVDSHVGKAIFSKVIGPNGLLRGTT 473

Query: 659 LLSITH 664
            + +TH
Sbjct: 472 RVLVTH 455
>01142
          Length = 729

 Score = 43.5 bits (101), Expect = 3e-04,   Method: Composition-based stats.
 Identities = 38/131 (29%), Positives = 62/131 (47%), Gaps = 8/131 (6%)
 Frame = -1

Query: 543 HMFYIPQRPYMSLGSLRDQVIYPDSADDMREKGYTDQDLERILHSVHLYHIVQREGGWDA 602
           H+  +PQ P +  GSLR  +   D  D+     Y+D  L   L   HL   V       A
Sbjct: 669 HLTILPQDPVLFSGSLRMNL---DPFDE-----YSDSQLWTALDRAHLRRFVS---SLPA 523

Query: 603 VMDWK-----DVLSGGEKQRMGMARMFYHKPKYALLDECTSAVSIDVEGKIFQAAIGAGI 657
            + ++     D LS G++Q + +AR    + +  +LDE T+AV ++ +  I Q  + +  
Sbjct: 522 QLHFQCGEEGDSLSVGQRQLVCLARTLLRRSRVLILDEATAAVDMETDALI-QNTLRSAF 346

Query: 658 S---LLSITHR 665
           S   +L+I HR
Sbjct: 345 SVCTVLTIAHR 313
>38795
          Length = 792

 Score = 33.1 bits (74), Expect = 0.39,   Method: Compositional matrix adjust.
 Identities = 12/34 (35%), Positives = 22/34 (64%)
 Frame = +1

Query: 494 VASRLNFKVEEGMHLLITGPNGCGKSSLFRILSG 527
           +   L+F ++    + + GPNG GKS+L +++SG
Sbjct: 682 IYQNLDFGIDLDTRVALVGPNGAGKSTLLKLISG 783
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|84662745|ref|NP_032165.3| guanine nucleotide binding
protein, alpha q polypeptide [Mus musculus]
         (359 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

11965                                                                 252   1e-67
13527                                                                 162   2e-40
20516                                                                 118   4e-27
29196                                                                 105   2e-23
08153                                                                  45   6e-05
09827                                                                  44   8e-05
11378                                                                  41   0.001
10862                                                                  40   0.001
34094                                                                  40   0.001
18949                                                                  35   0.045
15745                                                                  31   0.75 
18208                                                                  30   1.0  
25041                                                                  27   9.2  
>11965
          Length = 3256

 Score =  252 bits (644), Expect = 1e-67,   Method: Compositional matrix adjust.
 Identities = 123/221 (55%), Positives = 155/221 (70%)
 Frame = +1

Query: 138 DPGIQECYDRRREYQLSDSTKYYLNDLDRVADPSYLPTQQDVLRVRVPTTGIIEYPFDLQ 197
           D G+Q+C+ R  EYQL+DS KY+L+DLDR+    Y+PT+QD+LR RV TTGI+E  F  +
Sbjct: 1   DSGVQDCFSRSNEYQLNDSAKYFLDDLDRLGTKDYMPTEQDILRTRVKTTGIVEVHFSFK 180

Query: 198 SVIFRMVDVGGQRSERRKWIHCFENVTSIMFLVALSEYDQVLVESDNENRMEESKALFRT 257
           ++ F++ DVGGQRSER+KWIHCFE+VT+I+F VA+SEYDQVL E +  NRM+ES  LF +
Sbjct: 181 NLNFKLFDVGGQRSERKKWIHCFEDVTAIIFCVAMSEYDQVLHEDETTNRMQESLKLFDS 360

Query: 258 IITYPWFQNSSVILFLNKKDLLEEKIMYSHLVDYFPEYDGPQRDAQAAREFILKMFVDLN 317
           I    WF ++S+ILFLNKKDL EEKI  S L   FPEY G Q   + A  +I   F   N
Sbjct: 361 ICNNKWFTDTSIILFLNKKDLFEEKIKKSPLTVCFPEYTGKQTYEEVA-AYIQAQFEAKN 537

Query: 318 PDSDKIIYSHFTCATDTENIRFVFAAVKDTILQLNLKEYNL 358
             S K IY H TCATDT NI+FVF AV D I+  NL+   L
Sbjct: 538 KSSQKEIYCHQTCATDTNNIQFVFDAVTDVIIANNLRGCGL 660
>13527
          Length = 1091

 Score =  162 bits (411), Expect = 2e-40,   Method: Compositional matrix adjust.
 Identities = 79/201 (39%), Positives = 117/201 (58%), Gaps = 2/201 (0%)
 Frame = -2

Query: 6    IMACCLSEEAKEARRINDEIXXXXXXXXXXXXXXXXXXXXGTGESGKSTFIKQMRIIHGS 65
            IM C LS E + A   +  I                    G GESGKST +KQM+IIH  
Sbjct: 1045 IMGCTLSAEERAAMERSKAIEKNLKEDGMQAAKDIKLLLLGAGESGKSTIVKQMKIIHEG 866

Query: 66   GYSDEDKRGFTKLVYQNIFTAMQAMIRAMDTLKIPYKYEHNKAHAQLVREV--DVEKVSA 123
            G++ ED + +  +V+ N   ++ A+IRAM TL IP+     ++ A++V +V   +E    
Sbjct: 865  GFTSEDNKQYRPVVFSNTIQSLVAIIRAMGTLSIPFGDNERESDAKMVLDVIARMEDTEP 686

Query: 124  FENPYVDAIKSLWNDPGIQECYDRRREYQLSDSTKYYLNDLDRVADPSYLPTQQDVLRVR 183
            F    + A++ LW D G+Q+C+ R  EYQL+DS KY+L+DLDR+    Y+PT+QD+LR R
Sbjct: 685  FSEELLAAMERLWMDSGVQDCFSRSNEYQLNDSAKYFLDDLDRLGTKDYMPTEQDILRTR 506

Query: 184  VPTTGIIEYPFDLQSVIFRMV 204
            V TTGI+E  F  +++ F+ V
Sbjct: 505  VKTTGIVEVHFSFKNLNFKYV 443
>20516
          Length = 534

 Score =  118 bits (295), Expect = 4e-27,   Method: Compositional matrix adjust.
 Identities = 72/159 (45%), Positives = 92/159 (57%), Gaps = 3/159 (1%)
 Frame = +2

Query: 200 IFRMVD--VGGQRSERRKWIHCFENVTSIMFLVALSEYDQVLVESDNENRMEESKALFRT 257
           IF +V    GGQRS+R+KW  CF  +TSI+FL A SE+DQVL+E    NR++ES  +F T
Sbjct: 53  IFFLVGEVTGGQRSQRQKWYQCFVGITSILFLAASSEFDQVLMEDRKTNRLQESCDIFET 232

Query: 258 IITYPWFQNSSVILFLNKKDLLEEKIMYSHLVDYFPEYDGPQRDAQAAREFILKMFVDLN 317
           II    F   S+ILFLNK DLL++K     L   F  + G  +    ++  I    V   
Sbjct: 233 IINNKSFSGVSIILFLNKMDLLQDKN*ACQLRRLFSRFSG*SQGH*CSQS-I*ASAV*FA 409

Query: 318 PD-SDKIIYSHFTCATDTENIRFVFAAVKDTILQLNLKE 355
           P  S +    HFT A DTENI+ VF  VKDTIL  NL+ 
Sbjct: 410 PT*SKQTFVHHFTTAIDTENIKHVFQDVKDTILHDNLRS 526
>29196
          Length = 431

 Score =  105 bits (263), Expect = 2e-23,   Method: Compositional matrix adjust.
 Identities = 60/146 (41%), Positives = 87/146 (59%), Gaps = 4/146 (2%)
 Frame = -2

Query: 131 AIKSLWNDPGIQECYDRRREYQLSDSTKYYLNDLDRVADPSYLPTQQD----VLRVRVPT 186
           A+K LW D G+QEC   R     + +    ++ +  +     + +Q +        R P 
Sbjct: 427 AMKRLWLDSGVQEC--SRAATNTN*TIPLNISWMI*IG*ALRITSQPNRTFCAPESRPPA 254

Query: 187 TGIIEYPFDLQSVIFRMVDVGGQRSERRKWIHCFENVTSIMFLVALSEYDQVLVESDNEN 246
                 P  L+++ F++ DVGGQRSER+KWIHCFE+VT+I+F VA+SEYDQVL E +  N
Sbjct: 253 L*RFISP--LKNLNFKLFDVGGQRSERKKWIHCFEDVTAIIFCVAMSEYDQVLHEDETTN 80

Query: 247 RMEESKALFRTIITYPWFQNSSVILF 272
           RM+ES  LF +I    WF ++S+ILF
Sbjct: 79  RMQESLKLFDSICNNKWFTDTSIILF 2
>08153
          Length = 1703

 Score = 44.7 bits (104), Expect = 6e-05,   Method: Compositional matrix adjust.
 Identities = 25/95 (26%), Positives = 49/95 (51%)
 Frame = +1

Query: 184 VPTTGIIEYPFDLQSVIFRMVDVGGQRSERRKWIHCFENVTSIMFLVALSEYDQVLVESD 243
           +PT G      + +++ F + DVGGQ   R  W H F+N   ++F          +V+S+
Sbjct: 169 IPTIGFNVETVEYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIF----------VVDSN 318

Query: 244 NENRMEESKALFRTIITYPWFQNSSVILFLNKKDL 278
           +  R+ E+K     ++     +++ +++F NK+DL
Sbjct: 319 DRERINEAKEELARMLNEDDLRDAIILVFANKQDL 423
>09827
          Length = 1201

 Score = 44.3 bits (103), Expect = 8e-05,   Method: Compositional matrix adjust.
 Identities = 24/95 (25%), Positives = 51/95 (53%)
 Frame = -3

Query: 184  VPTTGIIEYPFDLQSVIFRMVDVGGQRSERRKWIHCFENVTSIMFLVALSEYDQVLVESD 243
            +PT G      + +++ F + DVGGQ   R  W H F+N   ++F          +V+S+
Sbjct: 1028 IPTIGFNVETVEYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIF----------VVDSN 879

Query: 244  NENRMEESKALFRTIITYPWFQNSSVILFLNKKDL 278
            ++ R++E++     ++     +++ +++F NK+DL
Sbjct: 878  DKERVQEAREELTRMLNEDELRDAVLLVFANKQDL 774
>11378
          Length = 1688

 Score = 40.8 bits (94), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 32/123 (26%), Positives = 50/123 (40%), Gaps = 1/123 (0%)
 Frame = +3

Query: 156 STKYYLNDLDRVADPSYLPT-QQDVLRVRVPTTGIIEYPFDLQSVIFRMVDVGGQRSERR 214
           S K     LD     + L   + D +   VPT         +  + F   D+GG R  RR
Sbjct: 321 SGKLVFLGLDNAGKTTLLHMLKDDKMAQHVPTLHPTSEELSMGGMRFTTFDLGGHRQARR 500

Query: 215 KWIHCFENVTSIMFLVALSEYDQVLVESDNENRMEESKALFRTIITYPWFQNSSVILFLN 274
            W   F  V  I+F          LV+  +  R+ E+KA   +++T     N+ +++  N
Sbjct: 501 VWKDYFPAVDGIVF----------LVDVHDRERLVEAKAELDSLMTDEQVANAPILVLGN 650

Query: 275 KKD 277
           K D
Sbjct: 651 KID 659
>10862
          Length = 2896

 Score = 40.4 bits (93), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 27/103 (26%), Positives = 49/103 (47%), Gaps = 8/103 (7%)
 Frame = -3

Query: 196  LQSVIFRMVDVGGQRSERRKWIHCFENVTSIMFLVALSEYDQVLVESDNENRMEESKALF 255
            LQ   F + DVGGQ   R  W H +     ++F+V  ++ D          R++E++   
Sbjct: 2495 LQECQFNVWDVGGQDKIRPLWRHYYTGTQGLIFVVDCADRD----------RIDEARQEL 2346

Query: 256  RTIITYPWFQNSSVILFLNKKDL--------LEEKIMYSHLVD 290
              II     +++ +++F NK+DL        ++EK+  + L D
Sbjct: 2345 HRIINDREMRDAIILIFANKQDLPDAMKPHEIQEKLGLTRLRD 2217
>34094
          Length = 452

 Score = 40.0 bits (92), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 17/44 (38%), Positives = 27/44 (61%)
 Frame = +1

Query: 60  RIIHGSGYSDEDKRGFTKLVYQNIFTAMQAMIRAMDTLKIPYKY 103
           RIIH  GYS E+   +  +VY N   +M A++RAM+ L + + +
Sbjct: 103 RIIHEKGYSQEECLQYKPVVYSNAIQSMIAIVRAMNLLSVEFGH 234
>18949
          Length = 414

 Score = 35.0 bits (79), Expect = 0.045,   Method: Compositional matrix adjust.
 Identities = 25/108 (23%), Positives = 44/108 (40%)
 Frame = +3

Query: 170 PSYLPTQQDVLRVRVPTTGIIEYPFDLQSVIFRMVDVGGQRSERRKWIHCFENVTSIMFL 229
           P+ LPT ++                 +  + F   D+GG R  RR W   F  V  I+F+
Sbjct: 15  PTGLPTSEE---------------LSMGGMTFTTFDLGGHRQARRVWKDYFPAVDGIVFI 149

Query: 230 VALSEYDQVLVESDNENRMEESKALFRTIITYPWFQNSSVILFLNKKD 277
           V + + +          R+ E+KA   +++      +  V++  NK D
Sbjct: 150 VDVHDTE----------RITEAKAELDSLLRDDQIADIPVLVLGNKMD 263
>15745
          Length = 1183

 Score = 31.2 bits (69), Expect = 0.75,   Method: Compositional matrix adjust.
 Identities = 15/35 (42%), Positives = 19/35 (54%)
 Frame = +2

Query: 83  IFTAMQAMIRAMDTLKIPYKYEHNKAHAQLVREVD 117
           I TA +A IR  D       Y+   AH QLVR++D
Sbjct: 629 IATANEATIRGWDLRSKQQTYQMEGAHGQLVRDLD 733
>18208
          Length = 458

 Score = 30.4 bits (67), Expect = 1.0,   Method: Compositional matrix adjust.
 Identities = 24/88 (27%), Positives = 40/88 (45%), Gaps = 5/88 (5%)
 Frame = -1

Query: 169 DPSYLPTQQDVLRVRVPTTGIIEYPFDLQSV-----IFRMVDVGGQRSERRKWIHCFENV 223
           DPS++           PT G     F+++SV        + D+GGQR  R  W + FEN 
Sbjct: 230 DPSHI----------TPTQG-----FNIKSVQSKGFKLNVWDIGGQRRIRPYWKNYFENT 96

Query: 224 TSIMFLVALSEYDQVLVESDNENRMEES 251
             +++          +++S +  RMEE+
Sbjct: 95  DLLIY----------VIDSSDTKRMEET 42
>25041
          Length = 455

 Score = 27.3 bits (59), Expect = 9.2,   Method: Compositional matrix adjust.
 Identities = 13/51 (25%), Positives = 26/51 (50%)
 Frame = +3

Query: 58  QMRIIHGSGYSDEDKRGFTKLVYQNIFTAMQAMIRAMDTLKIPYKYEHNKA 108
           Q  +   + Y D++ +  TKL+Y+++F  +  +I A   + I +   H K 
Sbjct: 3   QTNVYQKALYFDKNTKSITKLIYKHLFVLI*FLIEARAVILILFYKLHEKG 155
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|30424655|ref|NP_776142.1| RAB6B, member RAS oncogene
family [Mus musculus]
         (208 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

26083                                                                 251   2e-67
33374                                                                 124   2e-35
08428                                                                 144   4e-35
34468                                                                 113   4e-26
05468                                                                 102   1e-22
17511                                                                 102   2e-22
07465                                                                  98   2e-21
14456                                                                  97   4e-21
13901                                                                  92   2e-19
30760                                                                  91   4e-19
33794                                                                  89   1e-18
01398                                                                  87   5e-18
01095                                                                  87   7e-18
32723                                                                  86   9e-18
26536                                                                  86   1e-17
13750                                                                  79   1e-15
07580                                                                  70   2e-15
33380                                                                  78   3e-15
01972                                                                  70   4e-15
19006                                                                  72   1e-13
11257                                                                  70   5e-13
11728                                                                  70   6e-13
35581                                                                  69   2e-12
29380                                                                  68   3e-12
13745                                                                  67   5e-12
34359                                                                  64   6e-12
34597                                                                  65   2e-11
00858                                                                  60   4e-10
19656                                                                  59   2e-09
36482                                                                  58   2e-09
27191                                                                  55   2e-08
25618                                                                  55   3e-08
12339                                                                  54   3e-08
14119                                                                  53   1e-07
31291                                                                  52   1e-07
14775                                                                  50   8e-07
19046                                                                  49   2e-06
09204                                                                  47   8e-06
00552                                                                  46   9e-06
24619                                                                  44   5e-05
33605                                                                  43   8e-05
10708                                                                  39   0.002
08153                                                                  38   0.002
09827                                                                  37   0.005
18509                                                                  36   0.011
10862                                                                  35   0.029
11378                                                                  32   0.23 
05331                                                                  28   1.9  
06994                                                                  28   3.0  
>26083
          Length = 432

 Score =  251 bits (640), Expect = 2e-67,   Method: Compositional matrix adjust.
 Identities = 119/127 (93%), Positives = 124/127 (97%)
 Frame = +1

Query: 1   MSAGGDFGNPLRKFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDR 60
           M++ G+FGNPLRKFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDR
Sbjct: 40  MTSSGEFGNPLRKFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDR 219

Query: 61  TVRLQLWDTAGQERFRSLIPSYIRDSTVAVVVYDITNLNSFQQTSKWIDDVRTERGSDVI 120
           T+RLQLWDTAGQERFRSLIPSYIRDS+VAVVVYDITN NSF QTSKWIDDVRTERGSDVI
Sbjct: 220 TIRLQLWDTAGQERFRSLIPSYIRDSSVAVVVYDITNANSFHQTSKWIDDVRTERGSDVI 399

Query: 121 IMLVGNK 127
           IMLVGNK
Sbjct: 400 IMLVGNK 420
>33374
          Length = 489

 Score =  124 bits (310), Expect(2) = 2e-35,   Method: Compositional matrix adjust.
 Identities = 54/117 (46%), Positives = 83/117 (70%)
 Frame = +1

Query: 50  FLSKTMYLEDRTVRLQLWDTAGQERFRSLIPSYIRDSTVAVVVYDITNLNSFQQTSKWID 109
           FL++T+ L+D TV+ ++WDTAGQER+ SL P Y R +  A+VVYDITN ++F +   W+ 
Sbjct: 139 FLTQTVCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNQDTFGRAKTWVK 318

Query: 110 DVRTERGSDVIIMLVGNKTDLADKRQITIEEGEQRAKELSVMFIETSAKTGYNVKQL 166
           +++ +   +++I L GNK DLA+KR +  EE +  A+E S++F+ETSAKT  NV  +
Sbjct: 319 ELQRQASPNIVIALAGNKADLANKRMVEFEEAQAYAEENSLLFMETSAKTAMNVNDI 489

 Score = 42.0 bits (97), Expect(2) = 2e-35,   Method: Compositional matrix adjust.
 Identities = 19/38 (50%), Positives = 26/38 (68%)
 Frame = +2

Query: 13 KFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDF 50
          +FKLV LGE +VGK+SL+ RF+   F    ++TIG  F
Sbjct: 29 QFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAF 142
>08428
          Length = 1109

 Score =  144 bits (362), Expect = 4e-35,   Method: Compositional matrix adjust.
 Identities = 63/169 (37%), Positives = 109/169 (64%)
 Frame = -3

Query: 11   LRKFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTVRLQLWDTA 70
            +R  K+  LG+  VGK+S++ RF+  S+  + ++TIG  F+SK++ ++    R Q+WDTA
Sbjct: 1077 MRDVKVCLLGDSGVGKSSIVLRFVTGSYRPSQESTIGASFMSKSLVVDGAGYRFQIWDTA 898

Query: 71   GQERFRSLIPSYIRDSTVAVVVYDITNLNSFQQTSKWIDDVRTERGSDVIIMLVGNKTDL 130
            GQE+FR+L P Y R +  AV+VYD+T   +F+    WI ++R+    ++++ + GNK DL
Sbjct: 897  GQEKFRALAPMYYRGAAAAVIVYDVTRPRTFKSVKSWIQELRSFGPPNIVLAIAGNKCDL 718

Query: 131  ADKRQITIEEGEQRAKELSVMFIETSAKTGYNVKQLFRRVASALPGMEN 179
             + R++  ++ ++ A  +S +F ETSA T  NV+++F  +A  LP  E+
Sbjct: 717  EELREVVEKDAQEYASSISAIFGETSAMTAVNVEEMFTELARQLPPEED 571
>34468
          Length = 1502

 Score =  113 bits (283), Expect = 4e-26,   Method: Compositional matrix adjust.
 Identities = 62/168 (36%), Positives = 97/168 (57%), Gaps = 5/168 (2%)
 Frame = +1

Query: 12  RKFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTVRLQLWDTAG 71
           R FK++ +G+ +VGKT L  RF    F +  +ATIG+DF  K++ ++   ++LQLWDTAG
Sbjct: 490 RIFKIIVIGDSNVGKTCLTYRFCLGKFPDKTEATIGVDFREKSIQVDSEHLKLQLWDTAG 669

Query: 72  QERFR-SLIPSYIRDSTVAVVVYDITNLNSFQQTSKWIDDVRTERGSDVII-MLVGNKTD 129
           QERFR S++  Y R+    V VYD+T ++SF+    WI++      +  I  +LVGNK D
Sbjct: 670 QERFRKSMVQHYYRNVHAVVFVYDMTKMSSFENMPAWIEECDRHNLTKYIPRILVGNKCD 849

Query: 130 LADKRQITIEEGEQRAKELSVMFIETSAK---TGYNVKQLFRRVASAL 174
           + ++  +     ++ A   ++   ETSAK      +V  +F  VA  L
Sbjct: 850 VVERIAVNTNLAQKFADAHNMPLFETSAKDDEKANHVDAIFMTVAHKL 993
>05468
          Length = 1558

 Score =  102 bits (253), Expect = 1e-22,   Method: Compositional matrix adjust.
 Identities = 59/162 (36%), Positives = 96/162 (59%), Gaps = 7/162 (4%)
 Frame = -3

Query: 14   FKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLE-DRTVRLQLWDTAGQ 72
            +K++ +GE   GKTS+I R+++  F   Y+ATIG+DF  K +  + D  +RLQLWD AGQ
Sbjct: 1538 YKILVIGELGTGKTSIIKRYVHQFFSQHYRATIGVDFALKVLNWDADTLIRLQLWDIAGQ 1359

Query: 73   ERFRSLIPSYIRDSTVAVVVYDITNLNSFQQTSKWIDD----VRTERGSDVIIMLVGNKT 128
            ERF ++   Y +++  A VV+D+T  ++F   +KW +D    V+   GS V  +L+ NK 
Sbjct: 1358 ERFGNMTRVYYKEAVGAFVVFDVTRASTFDAVTKWKNDLDSKVQLADGSPVPCVLLANKC 1179

Query: 129  DLADKRQI--TIEEGEQRAKELSVMFIETSAKTGYNVKQLFR 168
            D A +  +  T +  E  +++  + + ETSAK   N+ +  R
Sbjct: 1178 DQAKEGLVNNTSQMDEFCSEKGFIGWYETSAKENINIDEAAR 1053
>17511
          Length = 483

 Score =  102 bits (253), Expect = 2e-22,   Method: Compositional matrix adjust.
 Identities = 49/121 (40%), Positives = 78/121 (64%), Gaps = 4/121 (3%)
 Frame = -3

Query: 14  FKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTVRLQLWDTAGQE 73
            K++ LG+  VGKTSL+ +++   F N Y+ATIG DFL+K + ++DR V +Q+WDTAGQE
Sbjct: 364 LKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQIWDTAGQE 185

Query: 74  RFRSLIPSYIRDSTVAVVVYDITNLNSFQQTSKWIDDVRTERG----SDVIIMLVGNKTD 129
           RF+SL  ++ R +   V+V+D+T  N+F+    W D+   +       +   +++GNK D
Sbjct: 184 RFQSLGVAFYRGADCCVLVFDVTMPNTFRSLDSWRDEFLIQASPRDPENFPFVVIGNKID 5

Query: 130 L 130
           L
Sbjct: 4   L 2
>07465
          Length = 1103

 Score = 98.2 bits (243), Expect = 2e-21,   Method: Compositional matrix adjust.
 Identities = 53/145 (36%), Positives = 81/145 (55%)
 Frame = +3

Query: 27  TSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTVRLQLWDTAGQERFRSLIPSYIRDS 86
           +S+I R+    F   Y+ TIG+DFL + + +    VRL LWDTAGQE F ++  +Y R +
Sbjct: 240 SSMIQRYCKGIFTKDYKKTIGVDFLERQIEVGGEDVRLMLWDTAGQEEFDAITKAYYRGA 419

Query: 87  TVAVVVYDITNLNSFQQTSKWIDDVRTERGSDVIIMLVGNKTDLADKRQITIEEGEQRAK 146
              V+ +   + +SF+    W   V  E G ++ +++V NK DL D   +  EE E  AK
Sbjct: 420 QACVLAFSTVDRDSFEALETWKRKVEDEVG-EIGMVIVQNKIDLIDDAVVRPEEAENLAK 596

Query: 147 ELSVMFIETSAKTGYNVKQLFRRVA 171
           +L + F  TS K   NV ++FR +A
Sbjct: 597 KLRLRFYRTSVKENMNVDEVFRYLA 671
>14456
          Length = 1867

 Score = 97.1 bits (240), Expect = 4e-21,   Method: Compositional matrix adjust.
 Identities = 60/175 (34%), Positives = 97/175 (55%), Gaps = 6/175 (3%)
 Frame = -1

Query: 19   LGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTVRLQLWDTAGQERFRSL 78
            L +  VGK+SL+ RF+ + FD     TIG++FL+K + ++D T  +Q+WDTAGQERF+SL
Sbjct: 1123 LKQGGVGKSSLMNRFVSNKFDAQSFHTIGVEFLNKDVVVDDETYTMQIWDTAGQERFKSL 944

Query: 79   IPSYIRDSTVAVVVYDITNLNSFQQTSKWIDD----VRTERGSDVIIMLVGNKTDLADKR 134
               + R +   ++ + + ++ SF+  S W  +       + G     +++GNK D+ + R
Sbjct: 943  RTPFYRGADCCLLTFSVDSMQSFRNLSMWRKEFLYYADIQDGVTFPFVVLGNKIDV-EGR 767

Query: 135  QITIEEGEQRAKELS-VMFIETSAKTGYNVKQLFRRVASALPGMENVQE-KSKEG 187
            Q+T EE        S   + ETSAK   NV++ F      L  +E+ QE K+  G
Sbjct: 766  QVTNEEARSWCTANSNAPYFETSAKDATNVEKAFLAAVQRLREVEDQQEVKTAHG 602
>13901
          Length = 962

 Score = 92.0 bits (227), Expect = 2e-19,   Method: Compositional matrix adjust.
 Identities = 40/95 (42%), Positives = 64/95 (67%), Gaps = 1/95 (1%)
 Frame = -3

Query: 14  FKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRT-VRLQLWDTAGQ 72
           FK++ +G+ +VGKTS + R++ DSF   Y+ TIG+DF  K +   D+  ++LQLWD AGQ
Sbjct: 285 FKVIIIGDPTVGKTSFVQRYVNDSFRRDYKMTIGVDFALKVIRWSDKCNIKLQLWDIAGQ 106

Query: 73  ERFRSLIPSYIRDSTVAVVVYDITNLNSFQQTSKW 107
           ERF S+   Y +D+   +V++D+T  N++Q   +W
Sbjct: 105 ERFTSMTRVYYKDAHACIVMFDLTQKNTYQNAIRW 1
>30760
          Length = 596

 Score = 90.9 bits (224), Expect = 4e-19,   Method: Compositional matrix adjust.
 Identities = 56/165 (33%), Positives = 90/165 (54%), Gaps = 5/165 (3%)
 Frame = -1

Query: 15  KLVFLGEQSVGKTSLITRFMYDS--FDNTYQATIGIDFLSKTMYLEDR--TVRLQLWDTA 70
           K +  G+  VGK+S+   F  DS  F   Y  T G++ L K + + D    V L L+D+A
Sbjct: 524 KCIVTGDSGVGKSSICQVFHSDSAHFPKNYSMTTGVEVLVKLVNIPDSRDQVELYLFDSA 345

Query: 71  GQERFRSLIPSYIRDSTVAVVVYDITNLNSFQQTSKWIDDVRTERGSDVII-MLVGNKTD 129
           G+E F   +  +    +V +VVYD+T+  SF    +W++ VR  + + VI  +LV NKTD
Sbjct: 344 GKEIFSENVTKFWDQPSVVMVVYDVTDETSFSGCVRWLERVRAAKPNTVIPGVLVANKTD 165

Query: 130 LADKRQITIEEGEQRAKELSVMFIETSAKTGYNVKQLFRRVASAL 174
           L ++R+++ +EG+  A+   + + E SAK   N    F  +A A 
Sbjct: 164 LDERRRVSRKEGKDLAQSHGLEYFECSAKEMQNTDTPFFCLAHAF 30
>33794
          Length = 779

 Score = 88.6 bits (218), Expect = 1e-18,   Method: Compositional matrix adjust.
 Identities = 51/150 (34%), Positives = 83/150 (55%), Gaps = 3/150 (2%)
 Frame = -1

Query: 39  DNTYQATIGIDFLSKTMYLEDRTVRLQLWDTAGQERFRSLIPSYIRDSTVAVVVYDITNL 98
           D T      + + + T+ LE + V+LQ+WDT+GQ RF ++I SY R +   ++VYDITN 
Sbjct: 719 DCTSHILQTVAYKTTTILLEGKRVKLQIWDTSGQGRFCTIIRSYSRGAQGIILVYDITNK 540

Query: 99  NSFQQTSKWIDDVRTERGSDVIIMLVGNKTDLADKRQITIEEGEQRAKELSVMFIETSAK 158
            SF    +W+ +V  E    +  +LVGN+  LA KRQ+  ++ E  A   ++   E S  
Sbjct: 539 WSFDGIDRWLKEVE-EHAPGIPKVLVGNRLHLAYKRQVAAKQAETYASRNNMSCFEISPL 363

Query: 159 TGYNVKQLF---RRVASALPGMENVQEKSK 185
             +N+++ F    R+A    GME++   +K
Sbjct: 362 CDFNIRESFCELARMALHRNGMEHIWRSNK 273
>01398
          Length = 1421

 Score = 87.0 bits (214), Expect = 5e-18,   Method: Compositional matrix adjust.
 Identities = 47/145 (32%), Positives = 81/145 (55%), Gaps = 8/145 (5%)
 Frame = -2

Query: 72   QERFRSLIPSYIRDSTVAVVVYDITNLNSFQQTSKWIDDVRTE-RGSDVIIMLVGNKTDL 130
            QERFRS+  SY R+S   ++VYDIT  ++F+   +W ++ R        I +++G+K+D 
Sbjct: 1420 QERFRSITRSYYRNSVGVIIVYDITKRSTFENLKQWYEEARNHIEPHKAIFLVLGHKSDR 1241

Query: 131  ADKRQITIEEGEQRAKELSVMFIETSAKTGYNVKQLFRRVAS-ALPGMENVQEKSKEGMI 189
             D RQ+T  EG + A+   + F ETSAK+G+N++ +F ++A      +++   + +EG  
Sbjct: 1240 EDARQVTAREGRRFAEMHGLKFFETSAKSGHNIEDVFAQIAKDTYQHLQDGHIRLEEGWD 1061

Query: 190  DIK--LDKPQE----PPASEGGCSC 208
             +K    +P+E        E G  C
Sbjct: 1060 GVKQGFARPRETVHLAEGEESGGCC 986
>01095
          Length = 1745

 Score = 86.7 bits (213), Expect = 7e-18,   Method: Compositional matrix adjust.
 Identities = 46/116 (39%), Positives = 70/116 (60%)
 Frame = -1

Query: 91   VVYDITNLNSFQQTSKWIDDVRTERGSDVIIMLVGNKTDLADKRQITIEEGEQRAKELSV 150
            VVYDITN ++F +   W+ +++ +   +++I L GNK DLA+KR +  EE +  A+E S+
Sbjct: 1745 VVYDITNQDTFGRAKTWVKELQRQASPNIVIALAGNKADLANKRMVEFEEAQAYAEENSL 1566

Query: 151  MFIETSAKTGYNVKQLFRRVASALPGMENVQEKSKEGMIDIKLDKPQEPPASEGGC 206
            +F+ETSAKT  NV  +F  +A  LP  E     S+     ++L+  Q    SEGGC
Sbjct: 1565 LFMETSAKTAMNVNDIFLAIAKKLPKNEG-GGGSQPRQQGVRLNNEQSQQ-SEGGC 1404
>32723
          Length = 384

 Score = 86.3 bits (212), Expect = 9e-18,   Method: Compositional matrix adjust.
 Identities = 41/105 (39%), Positives = 63/105 (60%)
 Frame = +2

Query: 72  QERFRSLIPSYIRDSTVAVVVYDITNLNSFQQTSKWIDDVRTERGSDVIIMLVGNKTDLA 131
           QERFRS+  SY R +   ++VYD+ +  S++   +WI ++    G+ V+  LVGNK D  
Sbjct: 2   QERFRSITQSYYRSANALILVYDVCSQQSYESLPQWIHEIELYAGTKVLAFLVGNKIDQT 181

Query: 132 DKRQITIEEGEQRAKELSVMFIETSAKTGYNVKQLFRRVASALPG 176
           DKR+I    G++ A+   + F+ETSAK   NV++LF  +A  L  
Sbjct: 182 DKREIPTHIGKEFAERYEMRFLETSAKEADNVEKLFSTIAYQLTA 316
>26536
          Length = 829

 Score = 85.9 bits (211), Expect = 1e-17,   Method: Compositional matrix adjust.
 Identities = 48/136 (35%), Positives = 77/136 (56%), Gaps = 3/136 (2%)
 Frame = +2

Query: 43  QATIGIDFLSKTMYLEDRTVRLQLWDTAGQERFRSLIPSYIRDSTVAVVVYDITNLNSFQ 102
           + TI +  L+    + +R V     DTAGQE + S+   Y R     +VVY +T++ SFQ
Sbjct: 71  ERTIMLLSLTTMKMMMERRVSWTFLDTAGQEEYSSMREHYTRSGDGFIVVYSVTDVTSFQ 250

Query: 103 QTS---KWIDDVRTERGSDVIIMLVGNKTDLADKRQITIEEGEQRAKELSVMFIETSAKT 159
           +     +W+   R +  + +  +L GNKTDL   R++T EEG + A  L +++ ETSAKT
Sbjct: 251 EAEAVFRWL--TRFQDETSIHAVLCGNKTDLTSDRKVTPEEGRKMADRLGMLYFETSAKT 424

Query: 160 GYNVKQLFRRVASALP 175
           G NV Q++  +  ++P
Sbjct: 425 GDNVSQVYHGLLRSIP 472

 Score = 34.7 bits (78), Expect = 0.025,   Method: Compositional matrix adjust.
 Identities = 16/33 (48%), Positives = 21/33 (63%)
 Frame = +2

Query: 14  FKLVFLGEQSVGKTSLITRFMYDSFDNTYQATI 46
           +K+V LG   VGK+SL  RF  D+F + Y  TI
Sbjct: 488 YKIVMLGSGGVGKSSLTIRFTQDTFLDVYDPTI 586
>13750
          Length = 503

 Score = 79.3 bits (194), Expect = 1e-15,   Method: Compositional matrix adjust.
 Identities = 53/157 (33%), Positives = 80/157 (50%), Gaps = 4/157 (2%)
 Frame = -2

Query: 26  KTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRT----VRLQLWDTAGQERFRSLIPS 81
           KT L+ R+    F +    TI +     + + E RT    VR  LWDT G E +RSL  S
Sbjct: 502 KTCLLRRYQKGFFMDRTMPTIAV---LCSEFNESRTDPLNVRYTLWDTGGAETYRSLWVS 332

Query: 82  YIRDSTVAVVVYDITNLNSFQQTSKWIDDVRTERGSDVIIMLVGNKTDLADKRQITIEEG 141
           + R + VA++VYD+T   SF   +        +   +  ++ VG+KTDL + R I+ E G
Sbjct: 331 HFRGAQVALLVYDVTCEWSFLTATTVWRKALMKNIPEAQVIFVGSKTDLEENRVISTERG 152

Query: 142 EQRAKELSVMFIETSAKTGYNVKQLFRRVASALPGME 178
           +  A +    F ETS+ TG NV  +F  +A  L  ++
Sbjct: 151 QAFATQCGYTFFETSSVTGKNVDAVFWEIAFILARLQ 41
>07580
          Length = 921

 Score = 70.5 bits (171), Expect(2) = 2e-15,   Method: Compositional matrix adjust.
 Identities = 49/156 (31%), Positives = 82/156 (52%), Gaps = 7/156 (4%)
 Frame = +3

Query: 38  FDNTYQATIGIDFLSKTMYLEDRTVRLQLWDTAGQERFRSLIPSYIRDSTVAVVVYDIT- 96
           F   Y  TI  D   K + ++ +   L++ DTAG E+F ++   Y+++    ++ Y IT 
Sbjct: 135 FVEKYDPTIE-DSYRKQVEVDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFLLAYSITA 311

Query: 97  --NLNSFQQTSKWIDDVRTERGSDVIIMLVGNKTDLADKRQITIEEGEQRAKELSVMFIE 154
               N  Q+  + I  +R +   DV ++LVGNK DL D+R +  ++G+  A+  S  F+E
Sbjct: 312 QSTFNDLQELREQI--LRVKDTDDVPMLLVGNKCDLEDERVVGKDQGQGLARSFSCAFLE 485

Query: 155 TSAKTGYNVKQLF----RRVASALPGMENVQEKSKE 186
           TSAK   NV ++F    R++    P     + KSK+
Sbjct: 486 TSAKARINVNEIFMDLVRQINKKSPEQSGKRTKSKK 593

 Score = 28.5 bits (62), Expect(2) = 2e-15,   Method: Compositional matrix adjust.
 Identities = 12/28 (42%), Positives = 19/28 (67%)
 Frame = +2

Query: 11 LRKFKLVFLGEQSVGKTSLITRFMYDSF 38
          +R++KLV LG   VGK++L  +F+   F
Sbjct: 53 MREYKLVVLGSGGVGKSALTVQFVQGDF 136
>33380
          Length = 282

 Score = 77.8 bits (190), Expect = 3e-15,   Method: Compositional matrix adjust.
 Identities = 33/81 (40%), Positives = 54/81 (66%)
 Frame = +3

Query: 54  TMYLEDRTVRLQLWDTAGQERFRSLIPSYIRDSTVAVVVYDITNLNSFQQTSKWIDDVRT 113
           T++ +D+ V+LQ+WDTAGQER+R++  +Y R +   +++YD+TN  SF     W   ++T
Sbjct: 36  TVFRQDKRVKLQIWDTAGQERYRTITTAYYRGAMGFILMYDVTNEESFNAVQDWCTQIKT 215

Query: 114 ERGSDVIIMLVGNKTDLADKR 134
               +  ++LVGNK DL D+R
Sbjct: 216 YSWDNAQVVLVGNKCDLEDER 278
>01972
          Length = 2359

 Score = 70.1 bits (170), Expect(2) = 4e-15,   Method: Compositional matrix adjust.
 Identities = 40/140 (28%), Positives = 71/140 (50%)
 Frame = +3

Query: 42  YQATIGIDFLSKTMYLEDRTVRLQLWDTAGQERFRSLIPSYIRDSTVAVVVYDITNLNSF 101
           Y AT+G++      +     ++  +WDTAGQE+F  L   Y      AV+++D+T+  ++
Sbjct: 387 YVATLGVEVHPLLFHTSRGKLKFNVWDTAGQEKFGGLRDGYYIQGQCAVIMFDVTSRVTY 566

Query: 102 QQTSKWIDDVRTERGSDVIIMLVGNKTDLADKRQITIEEGEQRAKELSVMFIETSAKTGY 161
           +    W  D+      ++ I+L GNK D+ D++         R K L   + + SAK+ Y
Sbjct: 567 KNVPNWHRDL-VRVCENIPIVLCGNKVDIKDRKVKAKAIVFHRKKNLQ--YYDISAKSNY 737

Query: 162 NVKQLFRRVASALPGMENVQ 181
           N ++ F  +A  L G  N++
Sbjct: 738 NFEKPFLWLARKLVGDPNLE 797

 Score = 27.7 bits (60), Expect(2) = 4e-15,   Method: Compositional matrix adjust.
 Identities = 11/26 (42%), Positives = 17/26 (65%)
 Frame = +1

Query: 14  FKLVFLGEQSVGKTSLITRFMYDSFD 39
           FKLV +G+  VGKT+ + R +   F+
Sbjct: 304 FKLVLVGDGGVGKTTFVKRHVTGEFE 381
>19006
          Length = 568

 Score = 72.4 bits (176), Expect = 1e-13,   Method: Compositional matrix adjust.
 Identities = 44/123 (35%), Positives = 68/123 (55%), Gaps = 1/123 (0%)
 Frame = -2

Query: 9   NPLRKFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTVRLQLWD 68
           N   K KLV +G+ + GKT L+  F  D F   Y  T+  ++++  + ++ + V L LWD
Sbjct: 450 NGCHKEKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVAD-IEVDSKQVELALWD 274

Query: 69  TAGQERFRSLIPSYIRDSTVAVVVYDITNLNSFQQ-TSKWIDDVRTERGSDVIIMLVGNK 127
           TAGQE +  L P    D+ V ++ + I + +S +    KW  +VR     +V I+LVGNK
Sbjct: 273 TAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVR-HFCPNVPIILVGNK 97

Query: 128 TDL 130
            DL
Sbjct: 96  KDL 88
>11257
          Length = 1102

 Score = 70.5 bits (171), Expect = 5e-13,   Method: Compositional matrix adjust.
 Identities = 43/147 (29%), Positives = 80/147 (54%), Gaps = 7/147 (4%)
 Frame = -2

Query: 53   KTMYLEDRTVRLQLWDTAGQERFRSLIPSYIRDSTVAVVVYDITNLNSFQQTSKWIDD-- 110
            K + ++  T  +Q+WDTAGQER++SL   + R +   ++ + + NL S Q  S W D+  
Sbjct: 1053 KDVVVDGETFTMQIWDTAGQERYKSLRTPFYRGTDCCLLTFSVDNLKSLQSLSDWYDEFV 874

Query: 111  --VRTERGSDVIIMLVGNKTDLADKRQITIEEGEQRAKEL-SVMFIETSAKTGYNVKQLF 167
                 +  +    +++GNK D+ ++R+++ E+     +   ++ + ETSAK   NV+Q F
Sbjct: 873  NYADIQDSASFPFVIIGNKADI-EEREVSSEDAYNWCRTHGNLPYFETSAKDSLNVQQAF 697

Query: 168  RRVASALPGM-ENVQEK-SKEGMIDIK 192
              V   L  M E + E+ ++   +D+K
Sbjct: 696  LAVVRRLREMDEQMDERPTRTDTVDLK 616
>11728
          Length = 635

 Score = 70.1 bits (170), Expect = 6e-13,   Method: Compositional matrix adjust.
 Identities = 46/163 (28%), Positives = 82/163 (50%), Gaps = 14/163 (8%)
 Frame = -1

Query: 11  LRKFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTVRLQLWDTA 70
           ++  K V +G+ +VGKT L+  +  ++F   Y  T+  D  S  + ++ + + L LWDTA
Sbjct: 497 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTV-FDNYSANVMVDSKPINLGLWDTA 321

Query: 71  GQERFRSLIPSYIRDSTVAVVVYDITNLNSFQQT-SKWIDDVRTERGSDVIIMLVGNKTD 129
           GQE +  L P     + V ++ + + +  SF+   +KW  +V +    +  I+LVG K D
Sbjct: 320 GQEDYDRLRPLSYPQTDVFLICFSLISPASFENVKAKWYPEV-SHHCPNTPIILVGTKLD 144

Query: 130 LADKRQ------------ITIEEGEQRAKELSV-MFIETSAKT 159
           L + ++            IT  +G   AK++    ++E SA T
Sbjct: 143 LREDKETIEKLKEKKLAPITYPQGLAMAKDIGAGKYLECSALT 15
>35581
          Length = 364

 Score = 68.6 bits (166), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 36/88 (40%), Positives = 46/88 (52%), Gaps = 1/88 (1%)
 Frame = +2

Query: 8   GNPLRKFKLVFLGEQSVGKTSLITRFMYDSF-DNTYQATIGIDFLSKTMYLEDRTVRLQL 66
           GN    FK V LG+  VGKT L+ R   D F D+   +      L+           + L
Sbjct: 29  GNDTLYFKCVLLGDAGVGKTCLLNRLATDKFLDSPLTSLTTASLLTTVTLTSGVMASVDL 208

Query: 67  WDTAGQERFRSLIPSYIRDSTVAVVVYD 94
           WDTAGQER+RSL  SY RD+   ++VYD
Sbjct: 209 WDTAGQERYRSLTSSYYRDTKAVLIVYD 292
>29380
          Length = 853

 Score = 67.8 bits (164), Expect = 3e-12,   Method: Compositional matrix adjust.
 Identities = 32/94 (34%), Positives = 58/94 (61%), Gaps = 1/94 (1%)
 Frame = -2

Query: 86  STVAVVVYDITNLNSFQQTSKWIDDVRTERGSDVIIMLVGNKTDLADK-RQITIEEGEQR 144
           ++ A++VYD+   ++F +   W+ ++R +    V+I+L GNK DLA + R ++ E+ +  
Sbjct: 852 ASAAIIVYDVNIADTFSRALAWVKELRQQNTESVLIILAGNKVDLATQHRAVSFEDAQSF 673

Query: 145 AKELSVMFIETSAKTGYNVKQLFRRVASALPGME 178
           A+E  ++F E SAKTG  V ++F  +A+ L   E
Sbjct: 672 ARENGLLFAEVSAKTGMAVNEIFMTLANQLIQQE 571
>13745
          Length = 1045

 Score = 67.0 bits (162), Expect = 5e-12,   Method: Compositional matrix adjust.
 Identities = 43/142 (30%), Positives = 69/142 (48%), Gaps = 5/142 (3%)
 Frame = +2

Query: 72  QERFRSLIPSYIRDSTVAVVVYDITNLNSFQQTSKWIDDVRTERG----SDVIIMLVGNK 127
           QERF+SL  ++ R +   V+VYD+T  NSF+    W D+   +           +++GNK
Sbjct: 2   QERFQSLGVAFYRGADCCVLVYDVTAPNSFKNLDSWRDEFLIQASPRDPEHFPFVVLGNK 181

Query: 128 TDLADKRQITIEEGEQRAKELS-VMFIETSAKTGYNVKQLFRRVASALPGMENVQEKSKE 186
            DL D RQ++    +Q  +  + + + ETSAK G NV+  F+ +A      E   E   +
Sbjct: 182 VDL-DNRQVSTRRAQQWCQSKNDIPYYETSAKEGINVEMAFQTIAKNALEQETEAELIND 358

Query: 187 GMIDIKLDKPQEPPASEGGCSC 208
               I+L+     P +   C C
Sbjct: 359 FPDQIRLNSENNRPGNADNCQC 424
>34359
          Length = 1042

 Score = 63.5 bits (153), Expect(2) = 6e-12,   Method: Compositional matrix adjust.
 Identities = 35/121 (28%), Positives = 63/121 (52%)
 Frame = +3

Query: 14  FKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTVRLQLWDTAGQE 73
           FKLV +G +     +++ R +  S    Y AT+G++            +R  +WDTAGQE
Sbjct: 54  FKLVLVGGRWEWANNIVKRHVTGS*KK-YVATLGVEVHPLQFNTSRGLLRFNVWDTAGQE 230

Query: 74  RFRSLIPSYIRDSTVAVVVYDITNLNSFQQTSKWIDDVRTERGSDVIIMLVGNKTDLADK 133
           +F  L   Y    T A++++D+T+  +++    W  D+      ++ I+L GNK D+ D+
Sbjct: 231 KFGGLRDGYYIQGTCAIIMFDVTSRVTYKNVPNWHRDL-VRVCENIPIVLCGNKVDIKDR 407

Query: 134 R 134
           +
Sbjct: 408 K 410

 Score = 23.5 bits (49), Expect(2) = 6e-12,   Method: Compositional matrix adjust.
 Identities = 11/36 (30%), Positives = 22/36 (61%)
 Frame = +2

Query: 145 AKELSVMFIETSAKTGYNVKQLFRRVASALPGMENV 180
           ++E ++ + + SAK+ YN ++ F  +A  L G  N+
Sbjct: 434 SQEKNLQYYDISAKSNYNFEKPFLWLARKLVGDPNL 541
>34597
          Length = 773

 Score = 65.1 bits (157), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 30/75 (40%), Positives = 48/75 (64%)
 Frame = -2

Query: 100 SFQQTSKWIDDVRTERGSDVIIMLVGNKTDLADKRQITIEEGEQRAKELSVMFIETSAKT 159
           SF+   KW+ ++      DV  M++GNK D+ DKR ++ E GE  A+E S+ F+ETSAK+
Sbjct: 709 SFENIVKWLRNIDEHANEDVEKMILGNKCDMTDKRVVSKERGEAIAREHSIRFMETSAKS 530

Query: 160 GYNVKQLFRRVASAL 174
             N+++ F  +A A+
Sbjct: 529 NINIERAFCELAEAI 485
>00858
          Length = 1658

 Score = 60.5 bits (145), Expect = 4e-10,   Method: Compositional matrix adjust.
 Identities = 47/162 (29%), Positives = 84/162 (51%), Gaps = 1/162 (0%)
 Frame = -2

Query: 7    FGNPLRKFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTVRLQL 66
            +   + ++KLV +G   VGK++L  +   + F   Y  T   D   K + ++  T  L +
Sbjct: 1609 YTTQMTEYKLVVVGAGGVGKSALTIQLXQNHFVEEYDPTXE-DSXRKQVVIDGETCLLDI 1433

Query: 67   WDTAGQERFRSLIPSYIRDSTVAVVVYDITNLNSFQQTSKWIDDVRTERGSD-VIIMLVG 125
             DTAGQE   ++    +R     + V+ + NL SF+  +++ + ++  + +D V ++LVG
Sbjct: 1432 LDTAGQEEXSAMRDQCMRTGEGFLCVFAVXNLKSFEDINQYREQIKRVKDADEVPMVLVG 1253

Query: 126  NKTDLADKRQITIEEGEQRAKELSVMFIETSAKTGYNVKQLF 167
            NK DL   R +   +G+  A+   + ++ETSAKT   V   F
Sbjct: 1252 NKVDLP-IRNVEQRQGKHMAELYHIPYVETSAKTRQGVDDAF 1130
>19656
          Length = 428

 Score = 58.9 bits (141), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 32/105 (30%), Positives = 55/105 (52%), Gaps = 1/105 (0%)
 Frame = +3

Query: 11  LRKFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTVRLQLWDTA 70
           ++  K V +G+ +VGKT L+  +  ++F   Y  T+  D  S  + ++ R V L LWDTA
Sbjct: 105 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTV-FDNYSANVMVDGRPVNLGLWDTA 281

Query: 71  GQERFRSLIPSYIRDSTVAVVVYDITNLNSFQQT-SKWIDDVRTE 114
           GQE +  L P     + V ++ + + +  SF+   +KW  +V   
Sbjct: 282 GQEDYDRLRPLSYPQTDVFLLCFSVASPASFENIRAKWYPEVNHH 416
>36482
          Length = 686

 Score = 58.2 bits (139), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 44/135 (32%), Positives = 67/135 (49%), Gaps = 3/135 (2%)
 Frame = +2

Query: 29  LITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTVRLQLWDTAGQERFRSLIPSYIRDSTV 88
           L  RF+   F   Y  T+   +   T+ +ED  VRL++ DTAGQ  +      Y   +  
Sbjct: 2   LTVRFLTRRFIGEYCPTLESVYKYHTV-IEDDDVRLEILDTAGQGTY-PWKEGYALWADC 175

Query: 89  AVVVYDITNLNSFQ---QTSKWIDDVRTERGSDVIIMLVGNKTDLADKRQITIEEGEQRA 145
            V VY I +  S++   Q  + ++ VR  + + +  +L  NKTDL   RQ+T +EGE  A
Sbjct: 176 FVFVYSINDRQSYEELVQVKRQVESVR--KSTSLTAVLAANKTDLLHDRQVTQKEGEDLA 349

Query: 146 KELSVMFIETSAKTG 160
           +E+     E SA  G
Sbjct: 350 EEIGCRLYEVSASEG 394
>27191
          Length = 443

 Score = 55.1 bits (131), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 26/102 (25%), Positives = 49/102 (48%)
 Frame = +1

Query: 26  KTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTVRLQLWDTAGQERFRSLIPSYIRD 85
           KT LI  F    F+  YQ T+G+D+  K   +    +R+ +WD +G   +  +       
Sbjct: 1   KTCLIKHFCESKFNQGYQPTVGVDYGFKIQTVNGVDMRVHMWDLSGSNEYLDVRNELYTG 180

Query: 86  STVAVVVYDITNLNSFQQTSKWIDDVRTERGSDVIIMLVGNK 127
           S    +V+D++N  SF+    W+ ++        + ++VGN+
Sbjct: 181 SDAIFIVFDVSNTPSFEALDSWLREINRFATGSPLNVIVGNR 306
>25618
          Length = 475

 Score = 54.7 bits (130), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 31/100 (31%), Positives = 54/100 (54%), Gaps = 1/100 (1%)
 Frame = +3

Query: 110 DVRTERGSDVIIMLVGNKTDLA-DKRQITIEEGEQRAKELSVMFIETSAKTGYNVKQLFR 168
           ++R +    V+I+L GNK DLA + R ++ ++    A++  ++F E SAKTG  V ++F 
Sbjct: 51  ELRQQNAGSVLIVLAGNKADLASEHRAVSADDARTFAEDNGLIFAEVSAKTGMAVSEVFM 230

Query: 169 RVASALPGMENVQEKSKEGMIDIKLDKPQEPPASEGGCSC 208
            +A  L       + S +G   ++L + +E     GGC C
Sbjct: 231 TIAHKLVRRAEEGQGSXQGRERVRLSEAEEAS---GGCKC 341
>12339
          Length = 578

 Score = 54.3 bits (129), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 33/105 (31%), Positives = 55/105 (52%), Gaps = 5/105 (4%)
 Frame = -2

Query: 72  QERFRSLIPSYIRDSTVAVVVYDITNLNSFQQTSKW----IDDVRTERGSDVIIMLVGNK 127
           QERF+SL  ++ R +   ++VYD+T   +F     W    ++            +++GNK
Sbjct: 577 QERFQSLGVAFYRGADCCILVYDVTEXKTFDSLDSWQREFLNQASPRDPEHFPFVVIGNK 398

Query: 128 TDLADKRQITIEEGE-QRAKELSVMFIETSAKTGYNVKQLFRRVA 171
            DL D R +T + G+   + +  + + ETSAK   NV+Q F+ VA
Sbjct: 397 IDL-DNRVVTAKRGQGWCSTKGGIPYFETSAKEAINVEQAFQTVA 266
>14119
          Length = 602

 Score = 52.8 bits (125), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 25/76 (32%), Positives = 45/76 (59%), Gaps = 1/76 (1%)
 Frame = +1

Query: 100 SFQQTSKWIDDVRTERGSDVIIMLVGNKTDLA-DKRQITIEEGEQRAKELSVMFIETSAK 158
           +F +   W+ ++R +    V+I+L GNK DLA + R ++ ++    A++  ++F E SAK
Sbjct: 1   TFNRALAWVKELRQQNAGSVLIVLAGNKADLASEHRAVSADDARTFAEDNGLIFAEVSAK 180

Query: 159 TGYNVKQLFRRVASAL 174
           TG  V ++F  +A  L
Sbjct: 181 TGMAVSEVFMTIAHKL 228
>31291
          Length = 446

 Score = 52.4 bits (124), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 42/139 (30%), Positives = 65/139 (46%), Gaps = 17/139 (12%)
 Frame = -1

Query: 64  LQLWDTAGQERFRSLIPSYIRDSTVAVVVYDITNLNSFQQTS-KWIDDVRTERGSDVIIM 122
           LQLWDTAGQE +  L P    ++ V ++ + + +  S +    KW  ++R      V I+
Sbjct: 446 LQLWDTAGQEDYDRLRPLAYPNTDVFMLXFSLMSEASMKNVKVKWYPEIR-HHDPHVPIV 270

Query: 123 LVGNKTDLADKRQ------------ITIEEGEQRAKELSVM-FIETSAKTGYNVKQLFR- 168
           LVG K DL   ++            ++  +G   AK +    + E S+KT  N+K  F  
Sbjct: 269 LVGTKLDLRQDKEAVRKLRSSRQDPVSSNQGNDLAKAIKAKRYFECSSKTQENLKTAFEE 90

Query: 169 --RVASALPGMENVQEKSK 185
             RVA  + G  N + K K
Sbjct: 89  TVRVALNMDGQNNKRPKPK 33
>14775
          Length = 380

 Score = 49.7 bits (117), Expect = 8e-07,   Method: Compositional matrix adjust.
 Identities = 43/157 (27%), Positives = 62/157 (39%), Gaps = 4/157 (2%)
 Frame = -2

Query: 26  KTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRT----VRLQLWDTAGQERFRSLIPS 81
           KT L+ R+    F +    TI +     + + E RT    VR  LWDT G E +RSL  S
Sbjct: 379 KTCLLRRYQKGFFMDRTMPTIAV---LCSEFNESRTDPLNVRYTLWDTGGAETYRSLWVS 209

Query: 82  YIRDSTVAVVVYDITNLNSFQQTSKWIDDVRTERGSDVIIMLVGNKTDLADKRQITIEEG 141
           + R + VA++VYD                                         +T E G
Sbjct: 208 HFRGAQVALLVYD-----------------------------------------VTCERG 152

Query: 142 EQRAKELSVMFIETSAKTGYNVKQLFRRVASALPGME 178
           +  A +    F ETS+ TG NV  +F  +A  L  ++
Sbjct: 151 QAFATQCGYTFFETSSVTGKNVDAVFWEIAFILARLQ 41
>19046
          Length = 445

 Score = 48.5 bits (114), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 32/119 (26%), Positives = 59/119 (49%), Gaps = 6/119 (5%)
 Frame = -2

Query: 72  QERFRSLIPSYIRDSTVAVVVYDITNLNSFQQTSKWIDDV-RTERGSDVIIMLVGNKTDL 130
           QE F ++   Y+R     ++V+ +T+  SF+  + +   + R +      ++L  NK DL
Sbjct: 444 QEEFSAMREQYMRKGDGFLLVFSVTDFRSFENMANFHTQILRVKDRDSYPMILCANKVDL 265

Query: 131 ADKRQITIEEGEQRAKELSVMFIETSAK-TGYNVKQLFRRVASAL----PGMENVQEKS 184
             +R+++ E+    A  L + +IETSAK    NV   F +V   +    P ++N + K 
Sbjct: 264 VHQRKVSEEQVRDLATRLRIPYIETSAKDPPLNVDLAFHQVVRVIRAQPPHLKNQRHKH 88
>09204
          Length = 1051

 Score = 46.6 bits (109), Expect = 8e-06,   Method: Compositional matrix adjust.
 Identities = 26/102 (25%), Positives = 54/102 (52%), Gaps = 4/102 (3%)
 Frame = -3

Query: 74   RFRSLIPSYIRDSTVAVVVYDITNLNSFQQTSKWIDDVRTERGSDVIIMLVGNKTDLA-- 131
            R+ ++   Y R +  A++ +D+T+ +SF +   WI ++R +   +  + + G K DL   
Sbjct: 1049 RYEAMSRIYYRGAKAAILCFDLTDKSSFDRIRFWIGELR-QHEEECKLYICGTKFDLVHD 873

Query: 132  --DKRQITIEEGEQRAKELSVMFIETSAKTGYNVKQLFRRVA 171
              ++R +     +  A +      ETS+ TG N+++LF ++A
Sbjct: 872  DPERRAVPRSVAKALADDCMAEIYETSSMTGDNIEKLFTKIA 747
>00552
          Length = 455

 Score = 46.2 bits (108), Expect = 9e-06,   Method: Compositional matrix adjust.
 Identities = 22/54 (40%), Positives = 35/54 (64%)
 Frame = -1

Query: 12  RKFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTVRLQ 65
           R  K+V LG+  VGK+SL+ RF+ + FD     TIG++FL+K + ++  T  +Q
Sbjct: 449 RLLKVVLLGDGGVGKSSLMNRFVSNKFDAQSFHTIGVEFLTKDVVVDGETFTMQ 288

 Score = 45.4 bits (106), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 18/45 (40%), Positives = 28/45 (62%)
 Frame = -3

Query: 66  LWDTAGQERFRSLIPSYIRDSTVAVVVYDITNLNSFQQTSKWIDD 110
           +WDTAGQER++SL   + R +   ++ + + NL S Q  S W D+
Sbjct: 147 IWDTAGQERYKSLRTPFYRGTDCCLLTFSVDNLKSLQSLSDWYDE 13
>24619
          Length = 509

 Score = 43.9 bits (102), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 31/114 (27%), Positives = 54/114 (47%), Gaps = 6/114 (5%)
 Frame = -2

Query: 72  QERFRSLIPSYIRDSTVAVVVYDITNLNSFQQTSKWIDDVRTERGSDVIIM-LVGNKTDL 130
           QE F ++   Y+R     ++V+ + +  SF+    +   +   +  D   M L  NK DL
Sbjct: 508 QEEFSAMREQYMRKGDGFLLVFSVIDYQSFENMVNFHTQILRVKDRDTYPMILCANKVDL 329

Query: 131 ADKRQITIEEGEQRAKELSVMFIETSAK-TGYNVKQLFRRVASAL----PGMEN 179
             +R+++ E+    A  L + +IETSAK    NV   F +V   +    P ++N
Sbjct: 328 VHQRKVSEEQVRDLATRLRIPYIETSAKDPPLNVDLAFHQVVRVIRAQPPHLKN 167
>33605
          Length = 888

 Score = 43.1 bits (100), Expect = 8e-05,   Method: Compositional matrix adjust.
 Identities = 27/83 (32%), Positives = 44/83 (53%)
 Frame = +1

Query: 12  RKFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTVRLQLWDTAG 71
           ++ +L+ LG  + GKT+++ +F  +  D T   T+G +   KT  LE R  +L +WD  G
Sbjct: 493 KEVRLLMLGLDNAGKTTILKKFNGEDID-TISPTLGFNI--KT--LEHRGFKLNVWDVGG 657

Query: 72  QERFRSLIPSYIRDSTVAVVVYD 94
           Q+  RS   +Y   +   V V D
Sbjct: 658 QQSLRSYWRNYFESTDGLVWVVD 726
>10708
          Length = 2775

 Score = 38.5 bits (88), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 26/86 (30%), Positives = 38/86 (44%), Gaps = 2/86 (2%)
 Frame = -2

Query: 62   VRLQLWDTAGQERFRSLIPSYIRDSTVAVVVYDITNLNSFQQTSKWIDDVRTERGSDVII 121
            V L LWDTAGQE +  L P    D+ V ++ + I + +S +   + +D       S    
Sbjct: 2723 VELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKVDSRGAPFLSQCSH 2544

Query: 122  MLVGNKTDLAD--KRQITIEEGEQRA 145
               G +   A   K Q   +E E RA
Sbjct: 2543 HPCGKQKRFAQR*KHQTRADENETRA 2466
>08153
          Length = 1703

 Score = 38.1 bits (87), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 28/127 (22%), Positives = 59/127 (46%), Gaps = 6/127 (4%)
 Frame = +1

Query: 12  RKFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTVRLQLWDTAG 71
           ++ +++ +G  + GKT+++ +        T   TIG +  +    +E + +   +WD  G
Sbjct: 79  KEVRILMVGLDAAGKTTILYKLKLGEIVTTI-PTIGFNVET----VEYKNISFTVWDVGG 243

Query: 72  QERFRSLIPSYIRDSTVAVVVYDITNLNSFQQTSKWI------DDVRTERGSDVIIMLVG 125
           Q++ R L   Y +++   + V D  +     +  + +      DD+R     D II++  
Sbjct: 244 QDKIRPLWRHYFQNTQGLIFVVDSNDRERINEAKEELARMLNEDDLR-----DAIILVFA 408

Query: 126 NKTDLAD 132
           NK DL +
Sbjct: 409 NKQDLPN 429
>09827
          Length = 1201

 Score = 37.0 bits (84), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 25/120 (20%), Positives = 56/120 (46%), Gaps = 1/120 (0%)
 Frame = -3

Query: 12   RKFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTVRLQLWDTAG 71
            +  +++ +G  + GKT+++ +        T   TIG +  +    +E + +   +WD  G
Sbjct: 1118 KDMRILMVGLDAAGKTTILYKLKLGEIVTTI-PTIGFNVET----VEYKNISFTVWDVGG 954

Query: 72   QERFRSLIPSYIRDSTVAVVVYDITNLNSFQQTSKWIDDVRTE-RGSDVIIMLVGNKTDL 130
            Q++ R L   Y +++   + V D  +    Q+  + +  +  E    D ++++  NK DL
Sbjct: 953  QDKIRPLWRHYFQNTQGLIFVVDSNDKERVQEAREELTRMLNEDELRDAVLLVFANKQDL 774
>18509
          Length = 625

 Score = 35.8 bits (81), Expect = 0.011,   Method: Compositional matrix adjust.
 Identities = 21/58 (36%), Positives = 32/58 (55%)
 Frame = -3

Query: 110 DVRTERGSDVIIMLVGNKTDLADKRQITIEEGEQRAKELSVMFIETSAKTGYNVKQLF 167
           D R +   +V ++LVGNK DL   R +   +G+  A+   + ++ETSAKT   V   F
Sbjct: 554 D*RVKDADEVPMVLVGNKVDLP-IRNVEQRQGKHMAELYHIPYVETSAKTRQGVDDAF 384
>10862
          Length = 2896

 Score = 34.7 bits (78), Expect = 0.029,   Method: Compositional matrix adjust.
 Identities = 24/103 (23%), Positives = 45/103 (43%), Gaps = 4/103 (3%)
 Frame = -3

Query: 62   VRLQLWDTAGQERFRSLIPSYIRDSTVAVVVYDITNLNSFQQTSKWIDDVRTERG-SDVI 120
             +  +WD  GQ++ R L   Y   +   + V D  + +   +  + +  +  +R   D I
Sbjct: 2486 CQFNVWDVGGQDKIRPLWRHYYTGTQGLIFVVDCADRDRIDEARQELHRIINDREMRDAI 2307

Query: 121  IMLVGNKTDLAD---KRQITIEEGEQRAKELSVMFIETSAKTG 160
            I++  NK DL D     +I  + G  R ++ +     + A TG
Sbjct: 2306 ILIFANKQDLPDAMKPHEIQEKLGLTRLRDRNWYVQPSCATTG 2178
>11378
          Length = 1688

 Score = 31.6 bits (70), Expect = 0.23,   Method: Compositional matrix adjust.
 Identities = 29/116 (25%), Positives = 53/116 (45%), Gaps = 1/116 (0%)
 Frame = +3

Query: 15  KLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTVRLQLWDTAGQER 74
           KLVFLG  + GKT+L+   + D  D   Q    +   S+ + +    +R   +D  G  +
Sbjct: 327 KLVFLGLDNAGKTTLL-HMLKD--DKMAQHVPTLHPTSEELSMGG--MRFTTFDLGGHRQ 491

Query: 75  FRSLIPSYIRDSTVAVVVYDITNLNSFQQTSKWIDDVRT-ERGSDVIIMLVGNKTD 129
            R +   Y       V + D+ +     +    +D + T E+ ++  I+++GNK D
Sbjct: 492 ARRVWKDYFPAVDGIVFLVDVHDRERLVEAKAELDSLMTDEQVANAPILVLGNKID 659
>05331
          Length = 1202

 Score = 28.5 bits (62), Expect = 1.9,   Method: Compositional matrix adjust.
 Identities = 13/35 (37%), Positives = 21/35 (60%)
 Frame = +3

Query: 29  LITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTVR 63
           L++  +Y S DN++  TIG  FLS  +  + +T R
Sbjct: 342 LLSSEIYRSADNSHACTIGGSFLSSRLKFKQQTYR 446
>06994
          Length = 429

 Score = 28.1 bits (61), Expect = 3.0,   Method: Compositional matrix adjust.
 Identities = 12/28 (42%), Positives = 19/28 (67%)
 Frame = +3

Query: 11 LRKFKLVFLGEQSVGKTSLITRFMYDSF 38
          +R++KLV LG   VGK++L  +F+   F
Sbjct: 48 MREYKLVVLGSGGVGKSALTVQFVQGIF 131
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6754004|ref|NP_034431.1| guanine nucleotide binding
protein, alpha 11 [Mus musculus]
         (359 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

11965                                                                 252   2e-67
13527                                                                 182   2e-46
20516                                                                 122   2e-28
29196                                                                 109   2e-24
08153                                                                  47   1e-05
09827                                                                  47   1e-05
11378                                                                  40   0.001
34094                                                                  40   0.002
10862                                                                  38   0.006
18949                                                                  35   0.057
13950                                                                  32   0.27 
18208                                                                  30   1.2  
>11965
          Length = 3256

 Score =  252 bits (643), Expect = 2e-67,   Method: Compositional matrix adjust.
 Identities = 123/221 (55%), Positives = 156/221 (70%)
 Frame = +1

Query: 138 DPGVQECYDRRREFQLSDSAKYYLTDVDRIATVGYLPTQQDVLRVRVPTTGIIEYPFDLE 197
           D GVQ+C+ R  E+QL+DSAKY+L D+DR+ T  Y+PT+QD+LR RV TTGI+E  F  +
Sbjct: 1   DSGVQDCFSRSNEYQLNDSAKYFLDDLDRLGTKDYMPTEQDILRTRVKTTGIVEVHFSFK 180

Query: 198 NIIFRMVDVGGQRSERRKWIHCFENVTSIMFLVALSEYDQVLVESDNENRMEESKALFRT 257
           N+ F++ DVGGQRSER+KWIHCFE+VT+I+F VA+SEYDQVL E +  NRM+ES  LF +
Sbjct: 181 NLNFKLFDVGGQRSERKKWIHCFEDVTAIIFCVAMSEYDQVLHEDETTNRMQESLKLFDS 360

Query: 258 IITYPWFQNSSVILFLNKKDLLEDKILHSHLVDYFPEFDGPQRDAQAAREFILKMFVDLN 317
           I    WF ++S+ILFLNKKDL E+KI  S L   FPE+ G Q   + A  +I   F   N
Sbjct: 361 ICNNKWFTDTSIILFLNKKDLFEEKIKKSPLTVCFPEYTGKQTYEEVA-AYIQAQFEAKN 537

Query: 318 PDSDKIIYSHFTCATDTENIRFVFAAVKDTILQLNLKEYNL 358
             S K IY H TCATDT NI+FVF AV D I+  NL+   L
Sbjct: 538 KSSQKEIYCHQTCATDTNNIQFVFDAVTDVIIANNLRGCGL 660
>13527
          Length = 1091

 Score =  182 bits (462), Expect = 2e-46,   Method: Compositional matrix adjust.
 Identities = 86/201 (42%), Positives = 133/201 (66%), Gaps = 2/201 (0%)
 Frame = -2

Query: 6    MMACCLSDEVKESKRINAEIEKQLRRDKRDARRELKLLLLGTGESGKSTFIKQMRIIHGA 65
            +M C LS E + +   +  IEK L+ D   A +++KLLLLG GESGKST +KQM+IIH  
Sbjct: 1045 IMGCTLSAEERAAMERSKAIEKNLKEDGMQAAKDIKLLLLGAGESGKSTIVKQMKIIHEG 866

Query: 66   GYSEEDKRGFTKLVYQNIFTAMQAMVRAMETLKILYKYEQNKANALLIREV--DVEKVTT 123
            G++ ED + +  +V+ N   ++ A++RAM TL I +   + +++A ++ +V   +E    
Sbjct: 865  GFTSEDNKQYRPVVFSNTIQSLVAIIRAMGTLSIPFGDNERESDAKMVLDVIARMEDTEP 686

Query: 124  FEHQYVNAIKTLWSDPGVQECYDRRREFQLSDSAKYYLTDVDRIATVGYLPTQQDVLRVR 183
            F  + + A++ LW D GVQ+C+ R  E+QL+DSAKY+L D+DR+ T  Y+PT+QD+LR R
Sbjct: 685  FSEELLAAMERLWMDSGVQDCFSRSNEYQLNDSAKYFLDDLDRLGTKDYMPTEQDILRTR 506

Query: 184  VPTTGIIEYPFDLENIIFRMV 204
            V TTGI+E  F  +N+ F+ V
Sbjct: 505  VKTTGIVEVHFSFKNLNFKYV 443
>20516
          Length = 534

 Score =  122 bits (307), Expect = 2e-28,   Method: Compositional matrix adjust.
 Identities = 75/162 (46%), Positives = 94/162 (58%), Gaps = 2/162 (1%)
 Frame = +2

Query: 196 LENIIFRMVDV-GGQRSERRKWIHCFENVTSIMFLVALSEYDQVLVESDNENRMEESKAL 254
             NI F + +V GGQRS+R+KW  CF  +TSI+FL A SE+DQVL+E    NR++ES  +
Sbjct: 44  FRNIFFLVGEVTGGQRSQRQKWYQCFVGITSILFLAASSEFDQVLMEDRKTNRLQESCDI 223

Query: 255 FRTIITYPWFQNSSVILFLNKKDLLEDKILHSHLVDYFPEFDGPQRDAQAAREFILKMFV 314
           F TII    F   S+ILFLNK DLL+DK     L   F  F G  +    ++  I    V
Sbjct: 224 FETIINNKSFSGVSIILFLNKMDLLQDKN*ACQLRRLFSRFSG*SQGH*CSQS-I*ASAV 400

Query: 315 DLNPD-SDKIIYSHFTCATDTENIRFVFAAVKDTILQLNLKE 355
              P  S +    HFT A DTENI+ VF  VKDTIL  NL+ 
Sbjct: 401 *FAPT*SKQTFVHHFTTAIDTENIKHVFQDVKDTILHDNLRS 526
>29196
          Length = 431

 Score =  109 bits (272), Expect = 2e-24,   Method: Compositional matrix adjust.
 Identities = 63/146 (43%), Positives = 87/146 (59%), Gaps = 4/146 (2%)
 Frame = -2

Query: 131 AIKTLWSDPGVQECYDRRREFQLSDSAKYYLTDVDRIATVGYLPTQQD----VLRVRVPT 186
           A+K LW D GVQEC   R     + +    ++ +  I     + +Q +        R P 
Sbjct: 427 AMKRLWLDSGVQEC--SRAATNTN*TIPLNISWMI*IG*ALRITSQPNRTFCAPESRPPA 254

Query: 187 TGIIEYPFDLENIIFRMVDVGGQRSERRKWIHCFENVTSIMFLVALSEYDQVLVESDNEN 246
                 P  L+N+ F++ DVGGQRSER+KWIHCFE+VT+I+F VA+SEYDQVL E +  N
Sbjct: 253 L*RFISP--LKNLNFKLFDVGGQRSERKKWIHCFEDVTAIIFCVAMSEYDQVLHEDETTN 80

Query: 247 RMEESKALFRTIITYPWFQNSSVILF 272
           RM+ES  LF +I    WF ++S+ILF
Sbjct: 79  RMQESLKLFDSICNNKWFTDTSIILF 2
>08153
          Length = 1703

 Score = 47.0 bits (110), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 27/95 (28%), Positives = 49/95 (51%)
 Frame = +1

Query: 184 VPTTGIIEYPFDLENIIFRMVDVGGQRSERRKWIHCFENVTSIMFLVALSEYDQVLVESD 243
           +PT G      + +NI F + DVGGQ   R  W H F+N   ++F          +V+S+
Sbjct: 169 IPTIGFNVETVEYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIF----------VVDSN 318

Query: 244 NENRMEESKALFRTIITYPWFQNSSVILFLNKKDL 278
           +  R+ E+K     ++     +++ +++F NK+DL
Sbjct: 319 DRERINEAKEELARMLNEDDLRDAIILVFANKQDL 423
>09827
          Length = 1201

 Score = 47.0 bits (110), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 26/95 (27%), Positives = 51/95 (53%)
 Frame = -3

Query: 184  VPTTGIIEYPFDLENIIFRMVDVGGQRSERRKWIHCFENVTSIMFLVALSEYDQVLVESD 243
            +PT G      + +NI F + DVGGQ   R  W H F+N   ++F          +V+S+
Sbjct: 1028 IPTIGFNVETVEYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIF----------VVDSN 879

Query: 244  NENRMEESKALFRTIITYPWFQNSSVILFLNKKDL 278
            ++ R++E++     ++     +++ +++F NK+DL
Sbjct: 878  DKERVQEAREELTRMLNEDELRDAVLLVFANKQDL 774
>11378
          Length = 1688

 Score = 40.4 bits (93), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 27/102 (26%), Positives = 44/102 (43%)
 Frame = +3

Query: 176 QQDVLRVRVPTTGIIEYPFDLENIIFRMVDVGGQRSERRKWIHCFENVTSIMFLVALSEY 235
           + D +   VPT         +  + F   D+GG R  RR W   F  V  I+F       
Sbjct: 384 KDDKMAQHVPTLHPTSEELSMGGMRFTTFDLGGHRQARRVWKDYFPAVDGIVF------- 542

Query: 236 DQVLVESDNENRMEESKALFRTIITYPWFQNSSVILFLNKKD 277
              LV+  +  R+ E+KA   +++T     N+ +++  NK D
Sbjct: 543 ---LVDVHDRERLVEAKAELDSLMTDEQVANAPILVLGNKID 659
>34094
          Length = 452

 Score = 39.7 bits (91), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 18/40 (45%), Positives = 25/40 (62%)
 Frame = +1

Query: 60  RIIHGAGYSEEDKRGFTKLVYQNIFTAMQAMVRAMETLKI 99
           RIIH  GYS+E+   +  +VY N   +M A+VRAM  L +
Sbjct: 103 RIIHEKGYSQEECLQYKPVVYSNAIQSMIAIVRAMNLLSV 222
>10862
          Length = 2896

 Score = 38.1 bits (87), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 22/83 (26%), Positives = 41/83 (49%)
 Frame = -3

Query: 196  LENIIFRMVDVGGQRSERRKWIHCFENVTSIMFLVALSEYDQVLVESDNENRMEESKALF 255
            L+   F + DVGGQ   R  W H +     ++F+V  ++ D          R++E++   
Sbjct: 2495 LQECQFNVWDVGGQDKIRPLWRHYYTGTQGLIFVVDCADRD----------RIDEARQEL 2346

Query: 256  RTIITYPWFQNSSVILFLNKKDL 278
              II     +++ +++F NK+DL
Sbjct: 2345 HRIINDREMRDAIILIFANKQDL 2277
>18949
          Length = 414

 Score = 34.7 bits (78), Expect = 0.057,   Method: Compositional matrix adjust.
 Identities = 21/82 (25%), Positives = 37/82 (45%)
 Frame = +3

Query: 196 LENIIFRMVDVGGQRSERRKWIHCFENVTSIMFLVALSEYDQVLVESDNENRMEESKALF 255
           +  + F   D+GG R  RR W   F  V  I+F+V + + +          R+ E+KA  
Sbjct: 48  MGGMTFTTFDLGGHRQARRVWKDYFPAVDGIVFIVDVHDTE----------RITEAKAEL 197

Query: 256 RTIITYPWFQNSSVILFLNKKD 277
            +++      +  V++  NK D
Sbjct: 198 DSLLRDDQIADIPVLVLGNKMD 263
>13950
          Length = 708

 Score = 32.3 bits (72), Expect = 0.27,   Method: Compositional matrix adjust.
 Identities = 43/164 (26%), Positives = 63/164 (38%), Gaps = 8/164 (4%)
 Frame = -2

Query: 49  ESGKSTFIKQMRIIHGAGYSEEDKRGFTKLVYQNIFTAMQAMVRAMETLKILYKYEQNKA 108
           +SGK   ++   I+  AG     K    KLV Q          R  E ++++    QNKA
Sbjct: 578 KSGKKALVEVAHILSPAGRVVAPKADLKKLVAQRAIHGKMVTPRLSE-VQVISTVSQNKA 402

Query: 109 --NALLIREVDVEKV--TTFEHQYVNAIKTLWSDP---GVQECYDRRREFQLSDSAKYYL 161
             ++  I +    K+  T    +     K LWSD    G       +R       AK   
Sbjct: 401 QTSSPKISKSPGRKMPPTPKSIKKKTPGKKLWSDIVKYGKAATAAPQRRATPRQVAKITA 222

Query: 162 TDVDRIATVGYLP-TQQDVLRVRVPTTGIIEYPFDLENIIFRMV 204
                   VG  P T + + R+  PTTG ++ P  L  +I R V
Sbjct: 221 APKSAKKRVGKTPKTPKTLARLNAPTTGHVDSPDTL--VIGRKV 96
>18208
          Length = 458

 Score = 30.4 bits (67), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 18/68 (26%), Positives = 30/68 (44%)
 Frame = -1

Query: 184 VPTTGIIEYPFDLENIIFRMVDVGGQRSERRKWIHCFENVTSIMFLVALSEYDQVLVESD 243
            PT G        +     + D+GGQR  R  W + FEN   +++          +++S 
Sbjct: 215 TPTQGFNIKSVQSKGFKLNVWDIGGQRRIRPYWKNYFENTDLLIY----------VIDSS 66

Query: 244 NENRMEES 251
           +  RMEE+
Sbjct: 65  DTKRMEET 42

 Score = 30.0 bits (66), Expect = 1.4,   Method: Compositional matrix adjust.
 Identities = 12/22 (54%), Positives = 18/22 (81%)
 Frame = -1

Query: 38  RELKLLLLGTGESGKSTFIKQM 59
           REL++LLLG   +GK+T +KQ+
Sbjct: 305 RELRILLLGLDNAGKTTLLKQL 240
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|13195674|ref|NP_077249.1| RAB6A, member RAS oncogene
family [Mus musculus]
         (208 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

26083                                                                 250   3e-67
33374                                                                 120   1e-34
08428                                                                 139   9e-34
34468                                                                 115   1e-26
05468                                                                 103   7e-23
17511                                                                 101   2e-22
07465                                                                  98   2e-21
14456                                                                  94   5e-20
30760                                                                  93   1e-19
13901                                                                  92   1e-19
33794                                                                  89   1e-18
01398                                                                  86   2e-17
32723                                                                  85   2e-17
01095                                                                  85   2e-17
26536                                                                  85   2e-17
13750                                                                  79   1e-15
07580                                                                  70   2e-15
33380                                                                  77   5e-15
11257                                                                  76   1e-14
01972                                                                  67   3e-14
19006                                                                  73   8e-14
29380                                                                  70   8e-13
13745                                                                  69   1e-12
35581                                                                  69   2e-12
34359                                                                  63   3e-12
11728                                                                  68   3e-12
34597                                                                  66   8e-12
00858                                                                  59   2e-09
19656                                                                  59   2e-09
36482                                                                  57   5e-09
27191                                                                  55   2e-08
12339                                                                  54   4e-08
14119                                                                  52   3e-07
25618                                                                  51   3e-07
31291                                                                  49   2e-06
14775                                                                  48   3e-06
19046                                                                  47   7e-06
00552                                                                  46   9e-06
24619                                                                  45   3e-05
09204                                                                  45   3e-05
33605                                                                  43   9e-05
08153                                                                  39   0.002
09827                                                                  37   0.008
10708                                                                  36   0.010
18509                                                                  34   0.049
10862                                                                  34   0.054
11378                                                                  31   0.28 
28195                                                                  31   0.44 
05331                                                                  28   2.0  
06994                                                                  28   2.7  
22270                                                                  27   6.0  
>26083
          Length = 432

 Score =  250 bits (638), Expect = 3e-67,   Method: Compositional matrix adjust.
 Identities = 118/127 (92%), Positives = 124/127 (97%)
 Frame = +1

Query: 1   MSAGGDFGNPLRKFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDR 60
           M++ G+FGNPLRKFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDR
Sbjct: 40  MTSSGEFGNPLRKFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDR 219

Query: 61  TVRLQLWDTAGQERFRSLIPSYIRDSTVAVVVYDITNVNSFQQTTKWIDDVRTERGSDVI 120
           T+RLQLWDTAGQERFRSLIPSYIRDS+VAVVVYDITN NSF QT+KWIDDVRTERGSDVI
Sbjct: 220 TIRLQLWDTAGQERFRSLIPSYIRDSSVAVVVYDITNANSFHQTSKWIDDVRTERGSDVI 399

Query: 121 IMLVGNK 127
           IMLVGNK
Sbjct: 400 IMLVGNK 420
>33374
          Length = 489

 Score =  120 bits (302), Expect(2) = 1e-34,   Method: Compositional matrix adjust.
 Identities = 53/117 (45%), Positives = 82/117 (70%)
 Frame = +1

Query: 50  FLSKTMYLEDRTVRLQLWDTAGQERFRSLIPSYIRDSTVAVVVYDITNVNSFQQTTKWID 109
           FL++T+ L+D TV+ ++WDTAGQER+ SL P Y R +  A+VVYDITN ++F +   W+ 
Sbjct: 139 FLTQTVCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNQDTFGRAKTWVK 318

Query: 110 DVRTERGSDVIIMLVGNKTDLADKRQVSIEEGERKAKELNVMFIETSAKAGYNVKQL 166
           +++ +   +++I L GNK DLA+KR V  EE +  A+E +++F+ETSAK   NV  +
Sbjct: 319 ELQRQASPNIVIALAGNKADLANKRMVEFEEAQAYAEENSLLFMETSAKTAMNVNDI 489

 Score = 42.4 bits (98), Expect(2) = 1e-34,   Method: Compositional matrix adjust.
 Identities = 19/38 (50%), Positives = 26/38 (68%)
 Frame = +2

Query: 13 KFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDF 50
          +FKLV LGE +VGK+SL+ RF+   F    ++TIG  F
Sbjct: 29 QFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAF 142
>08428
          Length = 1109

 Score =  139 bits (350), Expect = 9e-34,   Method: Compositional matrix adjust.
 Identities = 62/168 (36%), Positives = 106/168 (63%)
 Frame = -3

Query: 11   LRKFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTVRLQLWDTA 70
            +R  K+  LG+  VGK+S++ RF+  S+  + ++TIG  F+SK++ ++    R Q+WDTA
Sbjct: 1077 MRDVKVCLLGDSGVGKSSIVLRFVTGSYRPSQESTIGASFMSKSLVVDGAGYRFQIWDTA 898

Query: 71   GQERFRSLIPSYIRDSTVAVVVYDITNVNSFQQTTKWIDDVRTERGSDVIIMLVGNKTDL 130
            GQE+FR+L P Y R +  AV+VYD+T   +F+    WI ++R+    ++++ + GNK DL
Sbjct: 897  GQEKFRALAPMYYRGAAAAVIVYDVTRPRTFKSVKSWIQELRSFGPPNIVLAIAGNKCDL 718

Query: 131  ADKRQVSIEEGERKAKELNVMFIETSAKAGYNVKQLFRRVAAALPGME 178
             + R+V  ++ +  A  ++ +F ETSA    NV+++F  +A  LP  E
Sbjct: 717  EELREVVEKDAQEYASSISAIFGETSAMTAVNVEEMFTELARQLPPEE 574
>34468
          Length = 1502

 Score =  115 bits (289), Expect = 1e-26,   Method: Compositional matrix adjust.
 Identities = 64/168 (38%), Positives = 98/168 (58%), Gaps = 5/168 (2%)
 Frame = +1

Query: 12  RKFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTVRLQLWDTAG 71
           R FK++ +G+ +VGKT L  RF    F +  +ATIG+DF  K++ ++   ++LQLWDTAG
Sbjct: 490 RIFKIIVIGDSNVGKTCLTYRFCLGKFPDKTEATIGVDFREKSIQVDSEHLKLQLWDTAG 669

Query: 72  QERFR-SLIPSYIRDSTVAVVVYDITNVNSFQQTTKWIDDVRTERGSDVII-MLVGNKTD 129
           QERFR S++  Y R+    V VYD+T ++SF+    WI++      +  I  +LVGNK D
Sbjct: 670 QERFRKSMVQHYYRNVHAVVFVYDMTKMSSFENMPAWIEECDRHNLTKYIPRILVGNKCD 849

Query: 130 LADKRQVSIEEGERKAKELNVMFIETSAK---AGYNVKQLFRRVAAAL 174
           + ++  V+    ++ A   N+   ETSAK      +V  +F  VA  L
Sbjct: 850 VVERIAVNTNLAQKFADAHNMPLFETSAKDDEKANHVDAIFMTVAHKL 993
>05468
          Length = 1558

 Score =  103 bits (256), Expect = 7e-23,   Method: Compositional matrix adjust.
 Identities = 60/162 (37%), Positives = 96/162 (59%), Gaps = 7/162 (4%)
 Frame = -3

Query: 14   FKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTM-YLEDRTVRLQLWDTAGQ 72
            +K++ +GE   GKTS+I R+++  F   Y+ATIG+DF  K + +  D  +RLQLWD AGQ
Sbjct: 1538 YKILVIGELGTGKTSIIKRYVHQFFSQHYRATIGVDFALKVLNWDADTLIRLQLWDIAGQ 1359

Query: 73   ERFRSLIPSYIRDSTVAVVVYDITNVNSFQQTTKWIDD----VRTERGSDVIIMLVGNKT 128
            ERF ++   Y +++  A VV+D+T  ++F   TKW +D    V+   GS V  +L+ NK 
Sbjct: 1358 ERFGNMTRVYYKEAVGAFVVFDVTRASTFDAVTKWKNDLDSKVQLADGSPVPCVLLANKC 1179

Query: 129  DLADKRQV--SIEEGERKAKELNVMFIETSAKAGYNVKQLFR 168
            D A +  V  + +  E  +++  + + ETSAK   N+ +  R
Sbjct: 1178 DQAKEGLVNNTSQMDEFCSEKGFIGWYETSAKENINIDEAAR 1053
>17511
          Length = 483

 Score =  101 bits (252), Expect = 2e-22,   Method: Compositional matrix adjust.
 Identities = 49/121 (40%), Positives = 78/121 (64%), Gaps = 4/121 (3%)
 Frame = -3

Query: 14  FKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTVRLQLWDTAGQE 73
            K++ LG+  VGKTSL+ +++   F N Y+ATIG DFL+K + ++DR V +Q+WDTAGQE
Sbjct: 364 LKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQIWDTAGQE 185

Query: 74  RFRSLIPSYIRDSTVAVVVYDITNVNSFQQTTKWIDDVRTERGS----DVIIMLVGNKTD 129
           RF+SL  ++ R +   V+V+D+T  N+F+    W D+   +       +   +++GNK D
Sbjct: 184 RFQSLGVAFYRGADCCVLVFDVTMPNTFRSLDSWRDEFLIQASPRDPENFPFVVIGNKID 5

Query: 130 L 130
           L
Sbjct: 4   L 2
>07465
          Length = 1103

 Score = 98.2 bits (243), Expect = 2e-21,   Method: Compositional matrix adjust.
 Identities = 54/145 (37%), Positives = 81/145 (55%)
 Frame = +3

Query: 27  TSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTVRLQLWDTAGQERFRSLIPSYIRDS 86
           +S+I R+    F   Y+ TIG+DFL + + +    VRL LWDTAGQE F ++  +Y R +
Sbjct: 240 SSMIQRYCKGIFTKDYKKTIGVDFLERQIEVGGEDVRLMLWDTAGQEEFDAITKAYYRGA 419

Query: 87  TVAVVVYDITNVNSFQQTTKWIDDVRTERGSDVIIMLVGNKTDLADKRQVSIEEGERKAK 146
              V+ +   + +SF+    W   V  E G ++ +++V NK DL D   V  EE E  AK
Sbjct: 420 QACVLAFSTVDRDSFEALETWKRKVEDEVG-EIGMVIVQNKIDLIDDAVVRPEEAENLAK 596

Query: 147 ELNVMFIETSAKAGYNVKQLFRRVA 171
           +L + F  TS K   NV ++FR +A
Sbjct: 597 KLRLRFYRTSVKENMNVDEVFRYLA 671
>14456
          Length = 1867

 Score = 93.6 bits (231), Expect = 5e-20,   Method: Compositional matrix adjust.
 Identities = 56/169 (33%), Positives = 93/169 (55%), Gaps = 5/169 (2%)
 Frame = -1

Query: 19   LGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTVRLQLWDTAGQERFRSL 78
            L +  VGK+SL+ RF+ + FD     TIG++FL+K + ++D T  +Q+WDTAGQERF+SL
Sbjct: 1123 LKQGGVGKSSLMNRFVSNKFDAQSFHTIGVEFLNKDVVVDDETYTMQIWDTAGQERFKSL 944

Query: 79   IPSYIRDSTVAVVVYDITNVNSFQQTTKWIDD----VRTERGSDVIIMLVGNKTDLADKR 134
               + R +   ++ + + ++ SF+  + W  +       + G     +++GNK D+ + R
Sbjct: 943  RTPFYRGADCCLLTFSVDSMQSFRNLSMWRKEFLYYADIQDGVTFPFVVLGNKIDV-EGR 767

Query: 135  QVSIEEGERKA-KELNVMFIETSAKAGYNVKQLFRRVAAALPGMESTQD 182
            QV+ EE         N  + ETSAK   NV++ F      L  +E  Q+
Sbjct: 766  QVTNEEARSWCTANSNAPYFETSAKDATNVEKAFLAAVQRLREVEDQQE 620
>30760
          Length = 596

 Score = 92.8 bits (229), Expect = 1e-19,   Method: Compositional matrix adjust.
 Identities = 59/172 (34%), Positives = 92/172 (53%), Gaps = 5/172 (2%)
 Frame = -1

Query: 15  KLVFLGEQSVGKTSLITRFMYDS--FDNTYQATIGIDFLSKTMYLEDR--TVRLQLWDTA 70
           K +  G+  VGK+S+   F  DS  F   Y  T G++ L K + + D    V L L+D+A
Sbjct: 524 KCIVTGDSGVGKSSICQVFHSDSAHFPKNYSMTTGVEVLVKLVNIPDSRDQVELYLFDSA 345

Query: 71  GQERFRSLIPSYIRDSTVAVVVYDITNVNSFQQTTKWIDDVRTERGSDVII-MLVGNKTD 129
           G+E F   +  +    +V +VVYD+T+  SF    +W++ VR  + + VI  +LV NKTD
Sbjct: 344 GKEIFSENVTKFWDQPSVVMVVYDVTDETSFSGCVRWLERVRAAKPNTVIPGVLVANKTD 165

Query: 130 LADKRQVSIEEGERKAKELNVMFIETSAKAGYNVKQLFRRVAAALPGMESTQ 181
           L ++R+VS +EG+  A+   + + E SAK   N    F  +A A   +   Q
Sbjct: 164 LDERRRVSRKEGKDLAQSHGLEYFECSAKEMQNTDTPFFCLAHAFHKLYQEQ 9
>13901
          Length = 962

 Score = 92.4 bits (228), Expect = 1e-19,   Method: Compositional matrix adjust.
 Identities = 40/95 (42%), Positives = 64/95 (67%), Gaps = 1/95 (1%)
 Frame = -3

Query: 14  FKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRT-VRLQLWDTAGQ 72
           FK++ +G+ +VGKTS + R++ DSF   Y+ TIG+DF  K +   D+  ++LQLWD AGQ
Sbjct: 285 FKVIIIGDPTVGKTSFVQRYVNDSFRRDYKMTIGVDFALKVIRWSDKCNIKLQLWDIAGQ 106

Query: 73  ERFRSLIPSYIRDSTVAVVVYDITNVNSFQQTTKW 107
           ERF S+   Y +D+   +V++D+T  N++Q   +W
Sbjct: 105 ERFTSMTRVYYKDAHACIVMFDLTQKNTYQNAIRW 1
>33794
          Length = 779

 Score = 89.4 bits (220), Expect = 1e-18,   Method: Compositional matrix adjust.
 Identities = 52/143 (36%), Positives = 80/143 (55%), Gaps = 3/143 (2%)
 Frame = -1

Query: 39  DNTYQATIGIDFLSKTMYLEDRTVRLQLWDTAGQERFRSLIPSYIRDSTVAVVVYDITNV 98
           D T      + + + T+ LE + V+LQ+WDT+GQ RF ++I SY R +   ++VYDITN 
Sbjct: 719 DCTSHILQTVAYKTTTILLEGKRVKLQIWDTSGQGRFCTIIRSYSRGAQGIILVYDITNK 540

Query: 99  NSFQQTTKWIDDVRTERGSDVIIMLVGNKTDLADKRQVSIEEGERKAKELNVMFIETSAK 158
            SF    +W+ +V  E    +  +LVGN+  LA KRQV+ ++ E  A   N+   E S  
Sbjct: 539 WSFDGIDRWLKEVE-EHAPGIPKVLVGNRLHLAYKRQVAAKQAETYASRNNMSCFEISPL 363

Query: 159 AGYNVKQLF---RRVAAALPGME 178
             +N+++ F    R+A    GME
Sbjct: 362 CDFNIRESFCELARMALHRNGME 294
>01398
          Length = 1421

 Score = 85.5 bits (210), Expect = 2e-17,   Method: Compositional matrix adjust.
 Identities = 40/101 (39%), Positives = 65/101 (64%), Gaps = 1/101 (0%)
 Frame = -2

Query: 72   QERFRSLIPSYIRDSTVAVVVYDITNVNSFQQTTKWIDDVRTE-RGSDVIIMLVGNKTDL 130
            QERFRS+  SY R+S   ++VYDIT  ++F+   +W ++ R        I +++G+K+D 
Sbjct: 1420 QERFRSITRSYYRNSVGVIIVYDITKRSTFENLKQWYEEARNHIEPHKAIFLVLGHKSDR 1241

Query: 131  ADKRQVSIEEGERKAKELNVMFIETSAKAGYNVKQLFRRVA 171
             D RQV+  EG R A+   + F ETSAK+G+N++ +F ++A
Sbjct: 1240 EDARQVTAREGRRFAEMHGLKFFETSAKSGHNIEDVFAQIA 1118
>32723
          Length = 384

 Score = 85.1 bits (209), Expect = 2e-17,   Method: Compositional matrix adjust.
 Identities = 40/105 (38%), Positives = 62/105 (59%)
 Frame = +2

Query: 72  QERFRSLIPSYIRDSTVAVVVYDITNVNSFQQTTKWIDDVRTERGSDVIIMLVGNKTDLA 131
           QERFRS+  SY R +   ++VYD+ +  S++   +WI ++    G+ V+  LVGNK D  
Sbjct: 2   QERFRSITQSYYRSANALILVYDVCSQQSYESLPQWIHEIELYAGTKVLAFLVGNKIDQT 181

Query: 132 DKRQVSIEEGERKAKELNVMFIETSAKAGYNVKQLFRRVAAALPG 176
           DKR++    G+  A+   + F+ETSAK   NV++LF  +A  L  
Sbjct: 182 DKREIPTHIGKEFAERYEMRFLETSAKEADNVEKLFSTIAYQLTA 316
>01095
          Length = 1745

 Score = 84.7 bits (208), Expect = 2e-17,   Method: Compositional matrix adjust.
 Identities = 44/117 (37%), Positives = 71/117 (60%), Gaps = 1/117 (0%)
 Frame = -1

Query: 91   VVYDITNVNSFQQTTKWIDDVRTERGSDVIIMLVGNKTDLADKRQVSIEEGERKAKELNV 150
            VVYDITN ++F +   W+ +++ +   +++I L GNK DLA+KR V  EE +  A+E ++
Sbjct: 1745 VVYDITNQDTFGRAKTWVKELQRQASPNIVIALAGNKADLANKRMVEFEEAQAYAEENSL 1566

Query: 151  MFIETSAKAGYNVKQLFRRVAAALPGME-STQDRSREDMIDIKLEKPQEQPVNEGGC 206
            +F+ETSAK   NV  +F  +A  LP  E     + R+  + +  E+ Q+   +EGGC
Sbjct: 1565 LFMETSAKTAMNVNDIFLAIAKKLPKNEGGGGSQPRQQGVRLNNEQSQQ---SEGGC 1404
>26536
          Length = 829

 Score = 84.7 bits (208), Expect = 2e-17,   Method: Compositional matrix adjust.
 Identities = 48/136 (35%), Positives = 76/136 (55%), Gaps = 3/136 (2%)
 Frame = +2

Query: 43  QATIGIDFLSKTMYLEDRTVRLQLWDTAGQERFRSLIPSYIRDSTVAVVVYDITNVNSFQ 102
           + TI +  L+    + +R V     DTAGQE + S+   Y R     +VVY +T+V SFQ
Sbjct: 71  ERTIMLLSLTTMKMMMERRVSWTFLDTAGQEEYSSMREHYTRSGDGFIVVYSVTDVTSFQ 250

Query: 103 QTT---KWIDDVRTERGSDVIIMLVGNKTDLADKRQVSIEEGERKAKELNVMFIETSAKA 159
           +     +W+   R +  + +  +L GNKTDL   R+V+ EEG + A  L +++ ETSAK 
Sbjct: 251 EAEAVFRWL--TRFQDETSIHAVLCGNKTDLTSDRKVTPEEGRKMADRLGMLYFETSAKT 424

Query: 160 GYNVKQLFRRVAAALP 175
           G NV Q++  +  ++P
Sbjct: 425 GDNVSQVYHGLLRSIP 472

 Score = 35.0 bits (79), Expect = 0.022,   Method: Compositional matrix adjust.
 Identities = 16/33 (48%), Positives = 21/33 (63%)
 Frame = +2

Query: 14  FKLVFLGEQSVGKTSLITRFMYDSFDNTYQATI 46
           +K+V LG   VGK+SL  RF  D+F + Y  TI
Sbjct: 488 YKIVMLGSGGVGKSSLTIRFTQDTFLDVYDPTI 586
>13750
          Length = 503

 Score = 79.0 bits (193), Expect = 1e-15,   Method: Compositional matrix adjust.
 Identities = 53/157 (33%), Positives = 79/157 (50%), Gaps = 4/157 (2%)
 Frame = -2

Query: 26  KTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRT----VRLQLWDTAGQERFRSLIPS 81
           KT L+ R+    F +    TI +     + + E RT    VR  LWDT G E +RSL  S
Sbjct: 502 KTCLLRRYQKGFFMDRTMPTIAV---LCSEFNESRTDPLNVRYTLWDTGGAETYRSLWVS 332

Query: 82  YIRDSTVAVVVYDITNVNSFQQTTKWIDDVRTERGSDVIIMLVGNKTDLADKRQVSIEEG 141
           + R + VA++VYD+T   SF   T        +   +  ++ VG+KTDL + R +S E G
Sbjct: 331 HFRGAQVALLVYDVTCEWSFLTATTVWRKALMKNIPEAQVIFVGSKTDLEENRVISTERG 152

Query: 142 ERKAKELNVMFIETSAKAGYNVKQLFRRVAAALPGME 178
           +  A +    F ETS+  G NV  +F  +A  L  ++
Sbjct: 151 QAFATQCGYTFFETSSVTGKNVDAVFWEIAFILARLQ 41
>07580
          Length = 921

 Score = 70.1 bits (170), Expect(2) = 2e-15,   Method: Compositional matrix adjust.
 Identities = 43/131 (32%), Positives = 74/131 (56%), Gaps = 1/131 (0%)
 Frame = +3

Query: 38  FDNTYQATIGIDFLSKTMYLEDRTVRLQLWDTAGQERFRSLIPSYIRDSTVAVVVYDITN 97
           F   Y  TI  D   K + ++ +   L++ DTAG E+F ++   Y+++    ++ Y IT 
Sbjct: 135 FVEKYDPTIE-DSYRKQVEVDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFLLAYSITA 311

Query: 98  VNSFQQTTKWIDDV-RTERGSDVIIMLVGNKTDLADKRQVSIEEGERKAKELNVMFIETS 156
            ++F    +  + + R +   DV ++LVGNK DL D+R V  ++G+  A+  +  F+ETS
Sbjct: 312 QSTFNDLQELREQILRVKDTDDVPMLLVGNKCDLEDERVVGKDQGQGLARSFSCAFLETS 491

Query: 157 AKAGYNVKQLF 167
           AKA  NV ++F
Sbjct: 492 AKARINVNEIF 524

 Score = 28.5 bits (62), Expect(2) = 2e-15,   Method: Compositional matrix adjust.
 Identities = 12/28 (42%), Positives = 19/28 (67%)
 Frame = +2

Query: 11 LRKFKLVFLGEQSVGKTSLITRFMYDSF 38
          +R++KLV LG   VGK++L  +F+   F
Sbjct: 53 MREYKLVVLGSGGVGKSALTVQFVQGDF 136
>33380
          Length = 282

 Score = 77.0 bits (188), Expect = 5e-15,   Method: Compositional matrix adjust.
 Identities = 33/81 (40%), Positives = 54/81 (66%)
 Frame = +3

Query: 54  TMYLEDRTVRLQLWDTAGQERFRSLIPSYIRDSTVAVVVYDITNVNSFQQTTKWIDDVRT 113
           T++ +D+ V+LQ+WDTAGQER+R++  +Y R +   +++YD+TN  SF     W   ++T
Sbjct: 36  TVFRQDKRVKLQIWDTAGQERYRTITTAYYRGAMGFILMYDVTNEESFNAVQDWCTQIKT 215

Query: 114 ERGSDVIIMLVGNKTDLADKR 134
               +  ++LVGNK DL D+R
Sbjct: 216 YSWDNAQVVLVGNKCDLEDER 278
>11257
          Length = 1102

 Score = 75.9 bits (185), Expect = 1e-14,   Method: Compositional matrix adjust.
 Identities = 45/147 (30%), Positives = 79/147 (53%), Gaps = 7/147 (4%)
 Frame = -2

Query: 53   KTMYLEDRTVRLQLWDTAGQERFRSLIPSYIRDSTVAVVVYDITNVNSFQQTTKWIDD-- 110
            K + ++  T  +Q+WDTAGQER++SL   + R +   ++ + + N+ S Q  + W D+  
Sbjct: 1053 KDVVVDGETFTMQIWDTAGQERYKSLRTPFYRGTDCCLLTFSVDNLKSLQSLSDWYDEFV 874

Query: 111  --VRTERGSDVIIMLVGNKTDLADKRQVSIEEGERKAKEL-NVMFIETSAKAGYNVKQLF 167
                 +  +    +++GNK D+ ++R+VS E+     +   N+ + ETSAK   NV+Q F
Sbjct: 873  NYADIQDSASFPFVIIGNKADI-EEREVSSEDAYNWCRTHGNLPYFETSAKDSLNVQQAF 697

Query: 168  RRVAAALPGMESTQDR--SREDMIDIK 192
              V   L  M+   D   +R D +D+K
Sbjct: 696  LAVVRRLREMDEQMDERPTRTDTVDLK 616
>01972
          Length = 2359

 Score = 66.6 bits (161), Expect(2) = 3e-14,   Method: Compositional matrix adjust.
 Identities = 40/135 (29%), Positives = 71/135 (52%)
 Frame = +3

Query: 42  YQATIGIDFLSKTMYLEDRTVRLQLWDTAGQERFRSLIPSYIRDSTVAVVVYDITNVNSF 101
           Y AT+G++      +     ++  +WDTAGQE+F  L   Y      AV+++D+T+  ++
Sbjct: 387 YVATLGVEVHPLLFHTSRGKLKFNVWDTAGQEKFGGLRDGYYIQGQCAVIMFDVTSRVTY 566

Query: 102 QQTTKWIDDVRTERGSDVIIMLVGNKTDLADKRQVSIEEGERKAKELNVMFIETSAKAGY 161
           +    W  D+      ++ I+L GNK D+ D R+V  +      K+ N+ + + SAK+ Y
Sbjct: 567 KNVPNWHRDL-VRVCENIPIVLCGNKVDIKD-RKVKAKAIVFHRKK-NLQYYDISAKSNY 737

Query: 162 NVKQLFRRVAAALPG 176
           N ++ F  +A  L G
Sbjct: 738 NFEKPFLWLARKLVG 782

 Score = 27.7 bits (60), Expect(2) = 3e-14,   Method: Compositional matrix adjust.
 Identities = 11/26 (42%), Positives = 17/26 (65%)
 Frame = +1

Query: 14  FKLVFLGEQSVGKTSLITRFMYDSFD 39
           FKLV +G+  VGKT+ + R +   F+
Sbjct: 304 FKLVLVGDGGVGKTTFVKRHVTGEFE 381
>19006
          Length = 568

 Score = 73.2 bits (178), Expect = 8e-14,   Method: Compositional matrix adjust.
 Identities = 44/123 (35%), Positives = 68/123 (55%), Gaps = 1/123 (0%)
 Frame = -2

Query: 9   NPLRKFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTVRLQLWD 68
           N   K KLV +G+ + GKT L+  F  D F   Y  T+  ++++  + ++ + V L LWD
Sbjct: 450 NGCHKEKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVAD-IEVDSKQVELALWD 274

Query: 69  TAGQERFRSLIPSYIRDSTVAVVVYDITNVNSFQQTT-KWIDDVRTERGSDVIIMLVGNK 127
           TAGQE +  L P    D+ V ++ + I + +S +    KW  +VR     +V I+LVGNK
Sbjct: 273 TAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVR-HFCPNVPIILVGNK 97

Query: 128 TDL 130
            DL
Sbjct: 96  KDL 88
>29380
          Length = 853

 Score = 69.7 bits (169), Expect = 8e-13,   Method: Compositional matrix adjust.
 Identities = 39/124 (31%), Positives = 66/124 (53%), Gaps = 1/124 (0%)
 Frame = -2

Query: 86  STVAVVVYDITNVNSFQQTTKWIDDVRTERGSDVIIMLVGNKTDLADK-RQVSIEEGERK 144
           ++ A++VYD+   ++F +   W+ ++R +    V+I+L GNK DLA + R VS E+ +  
Sbjct: 852 ASAAIIVYDVNIADTFSRALAWVKELRQQNTESVLIILAGNKVDLATQHRAVSFEDAQSF 673

Query: 145 AKELNVMFIETSAKAGYNVKQLFRRVAAALPGMESTQDRSREDMIDIKLEKPQEQPVNEG 204
           A+E  ++F E SAK G  V ++F  +A  L   E    R+R     + L +   +     
Sbjct: 672 ARENGLLFAEVSAKTGMAVNEIFMTLANQLIQQEIDGSRNR----GVTLNRENGEA---S 514

Query: 205 GCSC 208
           GC C
Sbjct: 513 GCKC 502
>13745
          Length = 1045

 Score = 68.9 bits (167), Expect = 1e-12,   Method: Compositional matrix adjust.
 Identities = 45/142 (31%), Positives = 70/142 (49%), Gaps = 5/142 (3%)
 Frame = +2

Query: 72  QERFRSLIPSYIRDSTVAVVVYDITNVNSFQQTTKWIDDVRTERGS----DVIIMLVGNK 127
           QERF+SL  ++ R +   V+VYD+T  NSF+    W D+   +           +++GNK
Sbjct: 2   QERFQSLGVAFYRGADCCVLVYDVTAPNSFKNLDSWRDEFLIQASPRDPEHFPFVVLGNK 181

Query: 128 TDLADKRQVSIEEGERKAKELN-VMFIETSAKAGYNVKQLFRRVAAALPGMESTQDRSRE 186
            DL D RQVS    ++  +  N + + ETSAK G NV+  F+ +A      E+  +   +
Sbjct: 182 VDL-DNRQVSTRRAQQWCQSKNDIPYYETSAKEGINVEMAFQTIAKNALEQETEAELIND 358

Query: 187 DMIDIKLEKPQEQPVNEGGCSC 208
               I+L     +P N   C C
Sbjct: 359 FPDQIRLNSENNRPGNADNCQC 424
>35581
          Length = 364

 Score = 68.6 bits (166), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 36/88 (40%), Positives = 46/88 (52%), Gaps = 1/88 (1%)
 Frame = +2

Query: 8   GNPLRKFKLVFLGEQSVGKTSLITRFMYDSF-DNTYQATIGIDFLSKTMYLEDRTVRLQL 66
           GN    FK V LG+  VGKT L+ R   D F D+   +      L+           + L
Sbjct: 29  GNDTLYFKCVLLGDAGVGKTCLLNRLATDKFLDSPLTSLTTASLLTTVTLTSGVMASVDL 208

Query: 67  WDTAGQERFRSLIPSYIRDSTVAVVVYD 94
           WDTAGQER+RSL  SY RD+   ++VYD
Sbjct: 209 WDTAGQERYRSLTSSYYRDTKAVLIVYD 292
>34359
          Length = 1042

 Score = 62.8 bits (151), Expect(2) = 3e-12,   Method: Compositional matrix adjust.
 Identities = 35/121 (28%), Positives = 63/121 (52%)
 Frame = +3

Query: 14  FKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTVRLQLWDTAGQE 73
           FKLV +G +     +++ R +  S    Y AT+G++            +R  +WDTAGQE
Sbjct: 54  FKLVLVGGRWEWANNIVKRHVTGS*KK-YVATLGVEVHPLQFNTSRGLLRFNVWDTAGQE 230

Query: 74  RFRSLIPSYIRDSTVAVVVYDITNVNSFQQTTKWIDDVRTERGSDVIIMLVGNKTDLADK 133
           +F  L   Y    T A++++D+T+  +++    W  D+      ++ I+L GNK D+ D+
Sbjct: 231 KFGGLRDGYYIQGTCAIIMFDVTSRVTYKNVPNWHRDL-VRVCENIPIVLCGNKVDIKDR 407

Query: 134 R 134
           +
Sbjct: 408 K 410

 Score = 25.0 bits (53), Expect(2) = 3e-12,   Method: Compositional matrix adjust.
 Identities = 12/35 (34%), Positives = 21/35 (60%)
 Frame = +2

Query: 142 ERKAKELNVMFIETSAKAGYNVKQLFRRVAAALPG 176
            R ++E N+ + + SAK+ YN ++ F  +A  L G
Sbjct: 425 HRLSQEKNLQYYDISAKSNYNFEKPFLWLARKLVG 529
>11728
          Length = 635

 Score = 67.8 bits (164), Expect = 3e-12,   Method: Compositional matrix adjust.
 Identities = 39/135 (28%), Positives = 71/135 (52%), Gaps = 1/135 (0%)
 Frame = -1

Query: 11  LRKFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTVRLQLWDTA 70
           ++  K V +G+ +VGKT L+  +  ++F   Y  T+  D  S  + ++ + + L LWDTA
Sbjct: 497 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTV-FDNYSANVMVDSKPINLGLWDTA 321

Query: 71  GQERFRSLIPSYIRDSTVAVVVYDITNVNSFQQT-TKWIDDVRTERGSDVIIMLVGNKTD 129
           GQE +  L P     + V ++ + + +  SF+    KW  +V +    +  I+LVG K D
Sbjct: 320 GQEDYDRLRPLSYPQTDVFLICFSLISPASFENVKAKWYPEV-SHHCPNTPIILVGTKLD 144

Query: 130 LADKRQVSIEEGERK 144
           L + ++   +  E+K
Sbjct: 143 LREDKETIEKLKEKK 99
>34597
          Length = 773

 Score = 66.2 bits (160), Expect = 8e-12,   Method: Compositional matrix adjust.
 Identities = 35/90 (38%), Positives = 54/90 (60%), Gaps = 4/90 (4%)
 Frame = -2

Query: 100 SFQQTTKWIDDVRTERGSDVIIMLVGNKTDLADKRQVSIEEGERKAKELNVMFIETSAKA 159
           SF+   KW+ ++      DV  M++GNK D+ DKR VS E GE  A+E ++ F+ETSAK+
Sbjct: 709 SFENIVKWLRNIDEHANEDVEKMILGNKCDMTDKRVVSKERGEAIAREHSIRFMETSAKS 530

Query: 160 GYNVKQLFRRVAAAL----PGMESTQDRSR 185
             N+++ F  +A A+     G ES ++  R
Sbjct: 529 NINIERAFCELAEAILDKTAGRESAENPER 440
>00858
          Length = 1658

 Score = 58.5 bits (140), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 46/162 (28%), Positives = 83/162 (51%), Gaps = 1/162 (0%)
 Frame = -2

Query: 7    FGNPLRKFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTVRLQL 66
            +   + ++KLV +G   VGK++L  +   + F   Y  T   D   K + ++  T  L +
Sbjct: 1609 YTTQMTEYKLVVVGAGGVGKSALTIQLXQNHFVEEYDPTXE-DSXRKQVVIDGETCLLDI 1433

Query: 67   WDTAGQERFRSLIPSYIRDSTVAVVVYDITNVNSFQQTTKWIDDVRTERGSD-VIIMLVG 125
             DTAGQE   ++    +R     + V+ + N+ SF+   ++ + ++  + +D V ++LVG
Sbjct: 1432 LDTAGQEEXSAMRDQCMRTGEGFLCVFAVXNLKSFEDINQYREQIKRVKDADEVPMVLVG 1253

Query: 126  NKTDLADKRQVSIEEGERKAKELNVMFIETSAKAGYNVKQLF 167
            NK DL   R V   +G+  A+  ++ ++ETSAK    V   F
Sbjct: 1252 NKVDLP-IRNVEQRQGKHMAELYHIPYVETSAKTRQGVDDAF 1130
>19656
          Length = 428

 Score = 58.5 bits (140), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 32/105 (30%), Positives = 54/105 (51%), Gaps = 1/105 (0%)
 Frame = +3

Query: 11  LRKFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTVRLQLWDTA 70
           ++  K V +G+ +VGKT L+  +  ++F   Y  T+  D  S  + ++ R V L LWDTA
Sbjct: 105 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTV-FDNYSANVMVDGRPVNLGLWDTA 281

Query: 71  GQERFRSLIPSYIRDSTVAVVVYDITNVNSFQQT-TKWIDDVRTE 114
           GQE +  L P     + V ++ + + +  SF+    KW  +V   
Sbjct: 282 GQEDYDRLRPLSYPQTDVFLLCFSVASPASFENIRAKWYPEVNHH 416
>36482
          Length = 686

 Score = 57.0 bits (136), Expect = 5e-09,   Method: Compositional matrix adjust.
 Identities = 44/135 (32%), Positives = 67/135 (49%), Gaps = 3/135 (2%)
 Frame = +2

Query: 29  LITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTVRLQLWDTAGQERFRSLIPSYIRDSTV 88
           L  RF+   F   Y  T+   +   T+ +ED  VRL++ DTAGQ  +      Y   +  
Sbjct: 2   LTVRFLTRRFIGEYCPTLESVYKYHTV-IEDDDVRLEILDTAGQGTY-PWKEGYALWADC 175

Query: 89  AVVVYDITNVNSFQ---QTTKWIDDVRTERGSDVIIMLVGNKTDLADKRQVSIEEGERKA 145
            V VY I +  S++   Q  + ++ VR  + + +  +L  NKTDL   RQV+ +EGE  A
Sbjct: 176 FVFVYSINDRQSYEELVQVKRQVESVR--KSTSLTAVLAANKTDLLHDRQVTQKEGEDLA 349

Query: 146 KELNVMFIETSAKAG 160
           +E+     E SA  G
Sbjct: 350 EEIGCRLYEVSASEG 394
>27191
          Length = 443

 Score = 55.1 bits (131), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 26/102 (25%), Positives = 49/102 (48%)
 Frame = +1

Query: 26  KTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTVRLQLWDTAGQERFRSLIPSYIRD 85
           KT LI  F    F+  YQ T+G+D+  K   +    +R+ +WD +G   +  +       
Sbjct: 1   KTCLIKHFCESKFNQGYQPTVGVDYGFKIQTVNGVDMRVHMWDLSGSNEYLDVRNELYTG 180

Query: 86  STVAVVVYDITNVNSFQQTTKWIDDVRTERGSDVIIMLVGNK 127
           S    +V+D++N  SF+    W+ ++        + ++VGN+
Sbjct: 181 SDAIFIVFDVSNTPSFEALDSWLREINRFATGSPLNVIVGNR 306
>12339
          Length = 578

 Score = 54.3 bits (129), Expect = 4e-08,   Method: Compositional matrix adjust.
 Identities = 35/113 (30%), Positives = 57/113 (50%), Gaps = 5/113 (4%)
 Frame = -2

Query: 72  QERFRSLIPSYIRDSTVAVVVYDITNVNSFQQTTKW----IDDVRTERGSDVIIMLVGNK 127
           QERF+SL  ++ R +   ++VYD+T   +F     W    ++            +++GNK
Sbjct: 577 QERFQSLGVAFYRGADCCILVYDVTEXKTFDSLDSWQREFLNQASPRDPEHFPFVVIGNK 398

Query: 128 TDLADKRQVSIEEGE-RKAKELNVMFIETSAKAGYNVKQLFRRVAAALPGMES 179
            DL D R V+ + G+   + +  + + ETSAK   NV+Q F+ VA      ES
Sbjct: 397 IDL-DNRVVTAKRGQGWCSTKGGIPYFETSAKEAINVEQAFQTVAKNALAQES 242
>14119
          Length = 602

 Score = 51.6 bits (122), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 26/76 (34%), Positives = 44/76 (57%), Gaps = 1/76 (1%)
 Frame = +1

Query: 100 SFQQTTKWIDDVRTERGSDVIIMLVGNKTDLA-DKRQVSIEEGERKAKELNVMFIETSAK 158
           +F +   W+ ++R +    V+I+L GNK DLA + R VS ++    A++  ++F E SAK
Sbjct: 1   TFNRALAWVKELRQQNAGSVLIVLAGNKADLASEHRAVSADDARTFAEDNGLIFAEVSAK 180

Query: 159 AGYNVKQLFRRVAAAL 174
            G  V ++F  +A  L
Sbjct: 181 TGMAVSEVFMTIAHKL 228
>25618
          Length = 475

 Score = 51.2 bits (121), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 35/105 (33%), Positives = 54/105 (51%), Gaps = 6/105 (5%)
 Frame = +3

Query: 110 DVRTERGSDVIIMLVGNKTDLA-DKRQVSIEEGERKAKELNVMFIETSAKAGYNVKQLFR 168
           ++R +    V+I+L GNK DLA + R VS ++    A++  ++F E SAK G  V ++F 
Sbjct: 51  ELRQQNAGSVLIVLAGNKADLASEHRAVSADDARTFAEDNGLIFAEVSAKTGMAVSEVFM 230

Query: 169 RVAAAL-----PGMESTQDRSREDMIDIKLEKPQEQPVNEGGCSC 208
            +A  L      G  S Q R R     ++L + +E     GGC C
Sbjct: 231 TIAHKLVRRAEEGQGSXQGRER-----VRLSEAEEAS---GGCKC 341
>31291
          Length = 446

 Score = 48.5 bits (114), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 40/139 (28%), Positives = 64/139 (46%), Gaps = 17/139 (12%)
 Frame = -1

Query: 64  LQLWDTAGQERFRSLIPSYIRDSTVAVVVYDITNVNSFQQT-TKWIDDVRTERGSDVIIM 122
           LQLWDTAGQE +  L P    ++ V ++ + + +  S +    KW  ++R      V I+
Sbjct: 446 LQLWDTAGQEDYDRLRPLAYPNTDVFMLXFSLMSEASMKNVKVKWYPEIR-HHDPHVPIV 270

Query: 123 LVGNKTDLADKRQ------------VSIEEGERKAKELNVM-FIETSAKAGYNVKQLFR- 168
           LVG K DL   ++            VS  +G   AK +    + E S+K   N+K  F  
Sbjct: 269 LVGTKLDLRQDKEAVRKLRSSRQDPVSSNQGNDLAKAIKAKRYFECSSKTQENLKTAFEE 90

Query: 169 --RVAAALPGMESTQDRSR 185
             RVA  + G  + + + +
Sbjct: 89  TVRVALNMDGQNNKRPKPK 33
>14775
          Length = 380

 Score = 47.8 bits (112), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 42/157 (26%), Positives = 61/157 (38%), Gaps = 4/157 (2%)
 Frame = -2

Query: 26  KTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRT----VRLQLWDTAGQERFRSLIPS 81
           KT L+ R+    F +    TI +     + + E RT    VR  LWDT G E +RSL  S
Sbjct: 379 KTCLLRRYQKGFFMDRTMPTIAV---LCSEFNESRTDPLNVRYTLWDTGGAETYRSLWVS 209

Query: 82  YIRDSTVAVVVYDITNVNSFQQTTKWIDDVRTERGSDVIIMLVGNKTDLADKRQVSIEEG 141
           + R + VA++VYD+T                                          E G
Sbjct: 208 HFRGAQVALLVYDVT-----------------------------------------CERG 152

Query: 142 ERKAKELNVMFIETSAKAGYNVKQLFRRVAAALPGME 178
           +  A +    F ETS+  G NV  +F  +A  L  ++
Sbjct: 151 QAFATQCGYTFFETSSVTGKNVDAVFWEIAFILARLQ 41
>19046
          Length = 445

 Score = 46.6 bits (109), Expect = 7e-06,   Method: Compositional matrix adjust.
 Identities = 33/119 (27%), Positives = 59/119 (49%), Gaps = 6/119 (5%)
 Frame = -2

Query: 72  QERFRSLIPSYIRDSTVAVVVYDITNVNSFQQTTKWIDDV-RTERGSDVIIMLVGNKTDL 130
           QE F ++   Y+R     ++V+ +T+  SF+    +   + R +      ++L  NK DL
Sbjct: 444 QEEFSAMREQYMRKGDGFLLVFSVTDFRSFENMANFHTQILRVKDRDSYPMILCANKVDL 265

Query: 131 ADKRQVSIEEGERKAKELNVMFIETSAK-AGYNV----KQLFRRVAAALPGMESTQDRS 184
             +R+VS E+    A  L + +IETSAK    NV     Q+ R + A  P +++ + + 
Sbjct: 264 VHQRKVSEEQVRDLATRLRIPYIETSAKDPPLNVDLAFHQVVRVIRAQPPHLKNQRHKH 88
>00552
          Length = 455

 Score = 46.2 bits (108), Expect = 9e-06,   Method: Compositional matrix adjust.
 Identities = 22/54 (40%), Positives = 35/54 (64%)
 Frame = -1

Query: 12  RKFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTVRLQ 65
           R  K+V LG+  VGK+SL+ RF+ + FD     TIG++FL+K + ++  T  +Q
Sbjct: 449 RLLKVVLLGDGGVGKSSLMNRFVSNKFDAQSFHTIGVEFLTKDVVVDGETFTMQ 288

 Score = 43.1 bits (100), Expect = 8e-05,   Method: Compositional matrix adjust.
 Identities = 16/45 (35%), Positives = 28/45 (62%)
 Frame = -3

Query: 66  LWDTAGQERFRSLIPSYIRDSTVAVVVYDITNVNSFQQTTKWIDD 110
           +WDTAGQER++SL   + R +   ++ + + N+ S Q  + W D+
Sbjct: 147 IWDTAGQERYKSLRTPFYRGTDCCLLTFSVDNLKSLQSLSDWYDE 13
>24619
          Length = 509

 Score = 44.7 bits (104), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 33/114 (28%), Positives = 55/114 (48%), Gaps = 6/114 (5%)
 Frame = -2

Query: 72  QERFRSLIPSYIRDSTVAVVVYDITNVNSFQQTTKWIDDVRTERGSDVIIM-LVGNKTDL 130
           QE F ++   Y+R     ++V+ + +  SF+    +   +   +  D   M L  NK DL
Sbjct: 508 QEEFSAMREQYMRKGDGFLLVFSVIDYQSFENMVNFHTQILRVKDRDTYPMILCANKVDL 329

Query: 131 ADKRQVSIEEGERKAKELNVMFIETSAK-AGYNV----KQLFRRVAAALPGMES 179
             +R+VS E+    A  L + +IETSAK    NV     Q+ R + A  P +++
Sbjct: 328 VHQRKVSEEQVRDLATRLRIPYIETSAKDPPLNVDLAFHQVVRVIRAQPPHLKN 167
>09204
          Length = 1051

 Score = 44.7 bits (104), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 26/102 (25%), Positives = 53/102 (51%), Gaps = 4/102 (3%)
 Frame = -3

Query: 74   RFRSLIPSYIRDSTVAVVVYDITNVNSFQQTTKWIDDVRTERGSDVIIMLVGNKTDLA-- 131
            R+ ++   Y R +  A++ +D+T+ +SF +   WI ++R +   +  + + G K DL   
Sbjct: 1049 RYEAMSRIYYRGAKAAILCFDLTDKSSFDRIRFWIGELR-QHEEECKLYICGTKFDLVHD 873

Query: 132  --DKRQVSIEEGERKAKELNVMFIETSAKAGYNVKQLFRRVA 171
              ++R V     +  A +      ETS+  G N+++LF ++A
Sbjct: 872  DPERRAVPRSVAKALADDCMAEIYETSSMTGDNIEKLFTKIA 747
>33605
          Length = 888

 Score = 43.1 bits (100), Expect = 9e-05,   Method: Compositional matrix adjust.
 Identities = 27/83 (32%), Positives = 44/83 (53%)
 Frame = +1

Query: 12  RKFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTVRLQLWDTAG 71
           ++ +L+ LG  + GKT+++ +F  +  D T   T+G +   KT  LE R  +L +WD  G
Sbjct: 493 KEVRLLMLGLDNAGKTTILKKFNGEDID-TISPTLGFNI--KT--LEHRGFKLNVWDVGG 657

Query: 72  QERFRSLIPSYIRDSTVAVVVYD 94
           Q+  RS   +Y   +   V V D
Sbjct: 658 QQSLRSYWRNYFESTDGLVWVVD 726
>08153
          Length = 1703

 Score = 38.5 bits (88), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 29/132 (21%), Positives = 60/132 (45%), Gaps = 6/132 (4%)
 Frame = +1

Query: 12  RKFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTVRLQLWDTAG 71
           ++ +++ +G  + GKT+++ +        T   TIG +  +    +E + +   +WD  G
Sbjct: 79  KEVRILMVGLDAAGKTTILYKLKLGEIVTTI-PTIGFNVET----VEYKNISFTVWDVGG 243

Query: 72  QERFRSLIPSYIRDSTVAVVVYDITNVNSFQQTTKWI------DDVRTERGSDVIIMLVG 125
           Q++ R L   Y +++   + V D  +     +  + +      DD+R     D II++  
Sbjct: 244 QDKIRPLWRHYFQNTQGLIFVVDSNDRERINEAKEELARMLNEDDLR-----DAIILVFA 408

Query: 126 NKTDLADKRQVS 137
           NK DL +    S
Sbjct: 409 NKQDLPNAYSAS 444
>09827
          Length = 1201

 Score = 36.6 bits (83), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 25/120 (20%), Positives = 56/120 (46%), Gaps = 1/120 (0%)
 Frame = -3

Query: 12   RKFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTVRLQLWDTAG 71
            +  +++ +G  + GKT+++ +        T   TIG +  +    +E + +   +WD  G
Sbjct: 1118 KDMRILMVGLDAAGKTTILYKLKLGEIVTTI-PTIGFNVET----VEYKNISFTVWDVGG 954

Query: 72   QERFRSLIPSYIRDSTVAVVVYDITNVNSFQQTTKWIDDVRTE-RGSDVIIMLVGNKTDL 130
            Q++ R L   Y +++   + V D  +    Q+  + +  +  E    D ++++  NK DL
Sbjct: 953  QDKIRPLWRHYFQNTQGLIFVVDSNDKERVQEAREELTRMLNEDELRDAVLLVFANKQDL 774
>10708
          Length = 2775

 Score = 36.2 bits (82), Expect = 0.010,   Method: Compositional matrix adjust.
 Identities = 17/48 (35%), Positives = 27/48 (56%)
 Frame = -2

Query: 62   VRLQLWDTAGQERFRSLIPSYIRDSTVAVVVYDITNVNSFQQTTKWID 109
            V L LWDTAGQE +  L P    D+ V ++ + I + +S +   + +D
Sbjct: 2723 VELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKVD 2580
>18509
          Length = 625

 Score = 33.9 bits (76), Expect = 0.049,   Method: Compositional matrix adjust.
 Identities = 21/58 (36%), Positives = 32/58 (55%)
 Frame = -3

Query: 110 DVRTERGSDVIIMLVGNKTDLADKRQVSIEEGERKAKELNVMFIETSAKAGYNVKQLF 167
           D R +   +V ++LVGNK DL   R V   +G+  A+  ++ ++ETSAK    V   F
Sbjct: 554 D*RVKDADEVPMVLVGNKVDLP-IRNVEQRQGKHMAELYHIPYVETSAKTRQGVDDAF 384
>10862
          Length = 2896

 Score = 33.9 bits (76), Expect = 0.054,   Method: Compositional matrix adjust.
 Identities = 18/72 (25%), Positives = 33/72 (45%), Gaps = 1/72 (1%)
 Frame = -3

Query: 62   VRLQLWDTAGQERFRSLIPSYIRDSTVAVVVYDITNVNSFQQTTKWIDDVRTERG-SDVI 120
             +  +WD  GQ++ R L   Y   +   + V D  + +   +  + +  +  +R   D I
Sbjct: 2486 CQFNVWDVGGQDKIRPLWRHYYTGTQGLIFVVDCADRDRIDEARQELHRIINDREMRDAI 2307

Query: 121  IMLVGNKTDLAD 132
            I++  NK DL D
Sbjct: 2306 ILIFANKQDLPD 2271
>11378
          Length = 1688

 Score = 31.2 bits (69), Expect = 0.28,   Method: Compositional matrix adjust.
 Identities = 29/116 (25%), Positives = 53/116 (45%), Gaps = 1/116 (0%)
 Frame = +3

Query: 15  KLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTVRLQLWDTAGQER 74
           KLVFLG  + GKT+L+   + D  D   Q    +   S+ + +    +R   +D  G  +
Sbjct: 327 KLVFLGLDNAGKTTLL-HMLKD--DKMAQHVPTLHPTSEELSMGG--MRFTTFDLGGHRQ 491

Query: 75  FRSLIPSYIRDSTVAVVVYDITNVNSFQQTTKWIDDVRT-ERGSDVIIMLVGNKTD 129
            R +   Y       V + D+ +     +    +D + T E+ ++  I+++GNK D
Sbjct: 492 ARRVWKDYFPAVDGIVFLVDVHDRERLVEAKAELDSLMTDEQVANAPILVLGNKID 659
>28195
          Length = 435

 Score = 30.8 bits (68), Expect = 0.44,   Method: Compositional matrix adjust.
 Identities = 22/94 (23%), Positives = 42/94 (44%), Gaps = 3/94 (3%)
 Frame = -3

Query: 57  LEDRTVRLQLWDTAGQERFRSLIPSYIRDSTVAV-VVYDITN--VNSFQQTTKWIDDVRT 113
           LED    L+ WD     R R  +  ++R   +A+ +VYD  +  V+  Q   + +   RT
Sbjct: 376 LEDLLHCLRCWDVVTHGRGRHCLAHFVRAXCIALAIVYDXVSVEVHGLQGANEGV--ART 203

Query: 114 ERGSDVIIMLVGNKTDLADKRQVSIEEGERKAKE 147
           +     ++ ++  +  L D     +++G   A E
Sbjct: 202 QSVLHHLVYVLRAQNSLLDHTPXLVDDGVLDAVE 101
>05331
          Length = 1202

 Score = 28.5 bits (62), Expect = 2.0,   Method: Compositional matrix adjust.
 Identities = 13/35 (37%), Positives = 21/35 (60%)
 Frame = +3

Query: 29  LITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTVR 63
           L++  +Y S DN++  TIG  FLS  +  + +T R
Sbjct: 342 LLSSEIYRSADNSHACTIGGSFLSSRLKFKQQTYR 446
>06994
          Length = 429

 Score = 28.1 bits (61), Expect = 2.7,   Method: Compositional matrix adjust.
 Identities = 12/28 (42%), Positives = 19/28 (67%)
 Frame = +3

Query: 11 LRKFKLVFLGEQSVGKTSLITRFMYDSF 38
          +R++KLV LG   VGK++L  +F+   F
Sbjct: 48 MREYKLVVLGSGGVGKSALTVQFVQGIF 131
>22270
          Length = 330

 Score = 26.9 bits (58), Expect = 6.0,   Method: Compositional matrix adjust.
 Identities = 13/32 (40%), Positives = 21/32 (65%), Gaps = 1/32 (3%)
 Frame = +1

Query: 178 ESTQDRSREDMIDIKL-EKPQEQPVNEGGCSC 208
           +ST+++  EDM ++ L + P E    EGGC+C
Sbjct: 1   DSTENKPSEDMQEVVLKDSPNETKDPEGGCAC 96
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|71774133|ref|NP_035279.2| peptidylprolyl isomerase B
[Mus musculus]
         (216 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

03374                                                                 250   3e-67
07030                                                                 243   3e-65
07382                                                                 195   1e-50
00176                                                                 179   7e-46
05336                                                                 178   2e-45
23478                                                                 164   3e-41
06379                                                                 108   2e-40
12506                                                                  97   2e-39
12711                                                                 127   4e-30
11676                                                                 125   1e-29
15913                                                                 121   2e-28
03857                                                                 112   1e-25
05986                                                                  81   3e-16
14547                                                                  74   3e-14
02140                                                                  73   7e-14
08983                                                                  70   8e-13
23338                                                                  54   7e-08
15093                                                                  50   6e-07
21265                                                                  40   8e-04
27940                                                                  28   2.5  
>03374
          Length = 852

 Score =  250 bits (639), Expect = 3e-67,   Method: Compositional matrix adjust.
 Identities = 122/184 (66%), Positives = 143/184 (77%)
 Frame = +1

Query: 32  VANDKKKGPKVTVKVYFDLQIGDESVGRVVFGLFGKTVPKTVDNFVALATGEKGFGYKNS 91
           V  D+ KGPKVT KV+FD+ IG E  GRV  GLFGKTV KTV NF  LA   +G GYK S
Sbjct: 7   VVADESKGPKVTDKVFFDITIGGEPAGRVEIGLFGKTVEKTVRNFKELAEKPQGEGYKGS 186

Query: 92  KFHRVIKDFMIQXXXXXXXXXXXXKSIYGERFPDENFKLKHYGPGWVSMANAGKDTNGSQ 151
           KFHR+IKDFMIQ            +SIYGERF DENFKLKHYG GW+SMANAGKDTNGSQ
Sbjct: 187 KFHRIIKDFMIQGGDFTKGDGTGGRSIYGERFEDENFKLKHYGAGWLSMANAGKDTNGSQ 366

Query: 152 FFITTVKTSWLDGKHVVFGKVLEGMDVVRKVESTKTDSRDKPLKDVIIVDSGKIEVEKPF 211
           FFITT +TSWLDG+HVVFGK+L GMDVVRK+E++ TD+RD+P+KDV+I + G I V +PF
Sbjct: 367 FFITTKQTSWLDGRHVVFGKILSGMDVVRKIEASATDARDRPVKDVVIANCGVIAVAEPF 546

Query: 212 AIAK 215
           A++K
Sbjct: 547 AVSK 558
>07030
          Length = 2391

 Score =  243 bits (621), Expect = 3e-65,   Method: Compositional matrix adjust.
 Identities = 121/182 (66%), Positives = 139/182 (76%), Gaps = 5/182 (2%)
 Frame = +2

Query: 39  GPKVTVKVYFDLQIGDESVGRVVFGLFGKTVPKTVDNFVALATG-----EKGFGYKNSKF 93
           G KVT KV+FD++IG E  GR+V GLFG  VPKT  NF +LA G     +    YK SKF
Sbjct: 146 GLKVTDKVFFDIEIGGEKAGRIVIGLFGDIVPKTAKNFKSLAVGFKDKDDNTLTYKGSKF 325

Query: 94  HRVIKDFMIQXXXXXXXXXXXXKSIYGERFPDENFKLKHYGPGWVSMANAGKDTNGSQFF 153
           HRVIKDFMIQ            KSIYGE+F DENFKL HYG GW+SMANAGKDTNGSQFF
Sbjct: 326 HRVIKDFMIQGGDFTRGDGTGGKSIYGEKFADENFKLNHYGAGWLSMANAGKDTNGSQFF 505

Query: 154 ITTVKTSWLDGKHVVFGKVLEGMDVVRKVESTKTDSRDKPLKDVIIVDSGKIEVEKPFAI 213
           +TT  TSWLDG+HVVFGKVLEGM VVRK+ESTKTD RDKP KDV+I DSG+I+V+KPF++
Sbjct: 506 LTTKTTSWLDGRHVVFGKVLEGMSVVRKIESTKTDGRDKPHKDVVIADSGEIKVDKPFSV 685

Query: 214 AK 215
           +K
Sbjct: 686 SK 691
>07382
          Length = 1486

 Score =  195 bits (495), Expect = 1e-50,   Method: Compositional matrix adjust.
 Identities = 100/183 (54%), Positives = 121/183 (66%), Gaps = 2/183 (1%)
 Frame = +2

Query: 33  ANDKKKGPKVTVKVYFDLQIGDESVGRVVFGLFGKTVPKTVDNFVALATGEKGFGY--KN 90
           +  K+   +VT KV FD+ I  E  G +  GLFG  VPKTV+NFVAL +G+  FGY  K 
Sbjct: 101 SESKEDRLRVTKKVVFDISIAGEPAGSIEIGLFGDVVPKTVNNFVALXSGQNAFGYNYKG 280

Query: 91  SKFHRVIKDFMIQXXXXXXXXXXXXKSIYGERFPDENFKLKHYGPGWVSMANAGKDTNGS 150
           SKFHRVI DFMIQ            KSIYG+ F DE+F +KHYG GW+SMAN G +TNG 
Sbjct: 281 SKFHRVISDFMIQGGDFVHNNGSGSKSIYGDLFDDEDFSVKHYGSGWISMANRGPNTNGC 460

Query: 151 QFFITTVKTSWLDGKHVVFGKVLEGMDVVRKVESTKTDSRDKPLKDVIIVDSGKIEVEKP 210
           QFFIT     WLDG HVVFGKV++GM VVRK+E   T+S D PL D++I DS +   EK 
Sbjct: 461 QFFITLRDCPWLDGSHVVFGKVIDGMKVVRKIEDIDTNSVDAPLVDIVITDSRE---EKC 631

Query: 211 FAI 213
           +AI
Sbjct: 632 YAI 640
>00176
          Length = 1408

 Score =  179 bits (454), Expect = 7e-46,   Method: Compositional matrix adjust.
 Identities = 91/164 (55%), Positives = 108/164 (65%)
 Frame = -1

Query: 42  VTVKVYFDLQIGDESVGRVVFGLFGKTVPKTVDNFVALATGEKGFGYKNSKFHRVIKDFM 101
           +  +VYFD+ IG    GR+V  L    VPKT +NF AL T EKGFG+K S FHRVI  FM
Sbjct: 904 MVTRVYFDMTIGGXDAGRIVMELRTDVVPKTAENFRALCTMEKGFGFKGSSFHRVIPGFM 725

Query: 102 IQXXXXXXXXXXXXKSIYGERFPDENFKLKHYGPGWVSMANAGKDTNGSQFFITTVKTSW 161
            Q            KSIYG +F DENF LKH GPG +SMANAG  TNGSQFF+ T +TSW
Sbjct: 724 CQGGDFTNHNGTGGKSIYGAKFADENFNLKHTGPGILSMANAGPGTNGSQFFLCTAETSW 545

Query: 162 LDGKHVVFGKVLEGMDVVRKVESTKTDSRDKPLKDVIIVDSGKI 205
           LDGKHVVFGKV EGM+VV+ +E   + S  K  K V+I D G++
Sbjct: 544 LDGKHVVFGKVAEGMEVVKAIEKVGSQS-GKTSKPVVIKDCGQL 416
>05336
          Length = 1406

 Score =  178 bits (451), Expect = 2e-45,   Method: Compositional matrix adjust.
 Identities = 93/173 (53%), Positives = 116/173 (67%), Gaps = 1/173 (0%)
 Frame = +3

Query: 34  NDKKKGPKVTVKVYFDLQIGDESVGRVVFGLFGKTVPKTVDNFVALATGEKGFGYKNSKF 93
           +D+ K P+V    YFD+    + +GR+ F LF   VPKT +NF +L TGEKGFG+KNS F
Sbjct: 90  SDESKRPRV----YFDMTADGDEIGRIEFELFADVVPKTAENFRSLCTGEKGFGFKNSIF 257

Query: 94  HRVIKDFMIQXXXXXXXXXXXXKSIYGERFPDENFKLKHYGPGWVSMANAGKDTNGSQFF 153
           HRVI +FM Q            KSIYG +F DENF +KH  PG +SMANAG DTNGSQFF
Sbjct: 258 HRVIPEFMCQGGDITRGNGTGGKSIYGNKFEDENFTMKHTKPGLLSMANAGPDTNGSQFF 437

Query: 154 ITTVKTSWLDGKHVVFGKVLEGMDVVRKVESTKTDSR-DKPLKDVIIVDSGKI 205
           ITTV TSWLDG HVVFG+V +GMD+V ++E  K  SR  +  K + I D G++
Sbjct: 438 ITTVVTSWLDGCHVVFGEVSKGMDIVTEIE--KLGSRGGQTKKKIAIADCGEL 590
>23478
          Length = 909

 Score =  164 bits (414), Expect = 3e-41,   Method: Compositional matrix adjust.
 Identities = 83/174 (47%), Positives = 105/174 (60%), Gaps = 8/174 (4%)
 Frame = +1

Query: 40  PKVTVKVYFDLQIGDESVGRVVFGLFGKTVPKTVDNFVALATGEKG--------FGYKNS 91
           P    + +FD+ IGD+  GR+VF L+    PKT +NF AL TGEKG          YK +
Sbjct: 94  PGFRPRCFFDVSIGDQPGGRIVFELYSDECPKTCENFRALCTGEKGTSEKTGAVLHYKGA 273

Query: 92  KFHRVIKDFMIQXXXXXXXXXXXXKSIYGERFPDENFKLKHYGPGWVSMANAGKDTNGSQ 151
            FHRV+KDFM+Q            +SIYG  F DENFK KH     +SMAN GKDTNGSQ
Sbjct: 274 PFHRVVKDFMVQCGDFTKGDGTGGESIYGGHFADENFKFKHEKECLLSMANRGKDTNGSQ 453

Query: 152 FFITTVKTSWLDGKHVVFGKVLEGMDVVRKVESTKTDSRDKPLKDVIIVDSGKI 205
           FFITT     LD  HVVFG VL G +VV+K+E   TD+R +P  +V + + G++
Sbjct: 454 FFITTNPAPHLDNVHVVFGHVLSGQEVVKKIEQLPTDARSRPEVEVKVANCGEL 615
>06379
          Length = 1672

 Score =  108 bits (271), Expect(2) = 2e-40,   Method: Compositional matrix adjust.
 Identities = 67/149 (44%), Positives = 83/149 (55%), Gaps = 16/149 (10%)
 Frame = -1

Query: 84   KGFGYKNSKFHRVIKDFMIQXXXXXXXXXXXXKSIYGERFPD-------ENFKLK----- 131
            K   YK S+FHRVIKDFMIQ                G RF         E  + K     
Sbjct: 1069 KELTYKGSQFHRVIKDFMIQ----------------GGRFHQW*WHWWAEYIRRKVC**E 938

Query: 132  -HYGPGWVSMANAGKDTNGSQFF---ITTVKTSWLDGKHVVFGKVLEGMDVVRKVESTKT 187
                  W  +A  G+     Q+    ITT KT+WLDG+HVVFGKVLEGMDVVR++E+ KT
Sbjct: 937  LQAEALWGWLAIHGQLWQRHQWLSVLITTKKTTWLDGRHVVFGKVLEGMDVVRRIENMKT 758

Query: 188  DSRDKPLKDVIIVDSGKIEVEKPFAIAKE 216
             +RDKP KD +I DSG IE+E  F++AK+
Sbjct: 757  SARDKPEKDCVIADSGAIEMEGSFSVAKD 671

 Score = 73.6 bits (179), Expect(2) = 2e-40,   Method: Compositional matrix adjust.
 Identities = 39/71 (54%), Positives = 50/71 (70%), Gaps = 3/71 (4%)
 Frame = -3

Query: 17   LIVGSVVFLLLPGPSVA---NDKKKGPKVTVKVYFDLQIGDESVGRVVFGLFGKTVPKTV 73
            L+ G   FLL+   ++A   +DK KGPKVT KVYFD++IG E  GR+V GLFGKTVPKT 
Sbjct: 1316 LLSG*YSFLLVQAFALAENKSDKPKGPKVTDKVYFDIEIGGEKAGRIVIGLFGKTVPKTA 1137

Query: 74   DNFVALATGEK 84
            +NF  L  G++
Sbjct: 1136 ENFKQLCIGDQ 1104
>12506
          Length = 1056

 Score = 96.7 bits (239), Expect(2) = 2e-39,   Method: Compositional matrix adjust.
 Identities = 44/80 (55%), Positives = 59/80 (73%)
 Frame = -2

Query: 126 ENFKLKHYGPGWVSMANAGKDTNGSQFFITTVKTSWLDGKHVVFGKVLEGMDVVRKVEST 185
           +NF+L+H   G +SMAN+G +TNGSQFF+TT KT WLDGKHVVFG+V+EG+D+V K+E  
Sbjct: 389 KNFQLRHTAAGDLSMANSGPNTNGSQFFLTTXKTDWLDGKHVVFGRVIEGLDIVNKMEKC 210

Query: 186 KTDSRDKPLKDVIIVDSGKI 205
            T    KP   V I + G++
Sbjct: 209 GTKG-GKPTDKVTIANCGEL 153

 Score = 82.8 bits (203), Expect(2) = 2e-39,   Method: Compositional matrix adjust.
 Identities = 38/82 (46%), Positives = 51/82 (62%)
 Frame = -1

Query: 45  KVYFDLQIGDESVGRVVFGLFGKTVPKTVDNFVALATGEKGFGYKNSKFHRVIKDFMIQX 104
           +VY D++IG+ +VGR++  L    VPKT +NF  L T EKG+G+K S FHR+I  FM Q 
Sbjct: 633 QVYMDIKIGNRAVGRIIMQLRADVVPKTAENFRCLCTHEKGYGFKGSSFHRIIPQFMCQG 454

Query: 105 XXXXXXXXXXXKSIYGERFPDE 126
                      KSIYG++F DE
Sbjct: 453 GDFTNHNGTGGKSIYGKKFEDE 388
>12711
          Length = 1926

 Score =  127 bits (319), Expect = 4e-30,   Method: Compositional matrix adjust.
 Identities = 71/167 (42%), Positives = 95/167 (56%), Gaps = 1/167 (0%)
 Frame = -2

Query: 31  SVANDKKKGPKVTVKVYFDLQIGDESVGRVVFGLFGKTVPKTVDNFVALATGEKGFGYKN 90
           ++A  + + P +T++          S+G  V  L+ K  P T  NF  L    +G+ Y  
Sbjct: 464 TIAASRMQPPNITIET---------SMGTFVLELYWKHAPNTCRNFAELC--RRGY-YNG 321

Query: 91  SKFHRVIKDFMIQXXXXXXXXXXXXKSIYGERFPDE-NFKLKHYGPGWVSMANAGKDTNG 149
            KFHR+IKDFMIQ             SIYG+ F DE    LKH G G +SMAN+G +TNG
Sbjct: 320 IKFHRIIKDFMIQGGDPTGTGRGG-SSIYGKNFNDEIADDLKHTGAGILSMANSGPNTNG 144

Query: 150 SQFFITTVKTSWLDGKHVVFGKVLEGMDVVRKVESTKTDSRDKPLKD 196
           SQFFIT   T WLDGKH +FG++  GM V++++   +TD  DKPL D
Sbjct: 143 SQFFITLAPTQWLDGKHSIFGRISSGMTVIKRIGMVETDGNDKPLDD 3
>11676
          Length = 499

 Score =  125 bits (314), Expect = 1e-29,   Method: Compositional matrix adjust.
 Identities = 68/120 (56%), Positives = 80/120 (66%), Gaps = 9/120 (7%)
 Frame = -3

Query: 24  FLLLPGPSVA---NDKKKGPKVTVKVYFDLQIGDESVGRVVFGLFGKTVPKTVDNFVALA 80
           FLL+   ++A   +DK KGPKVT KVYFD++IG E  GR+V GLFGKTVPKT +NF  L 
Sbjct: 365 FLLVQAFALAENKSDKPKGPKVTDKVYFDIEIGGEKAGRIVIGLFGKTVPKTAENFKQLC 186

Query: 81  TGE------KGFGYKNSKFHRVIKDFMIQXXXXXXXXXXXXKSIYGERFPDENFKLKHYG 134
            G+      K   YK S+FHRVIKDFMIQ            +SIYGE+F DENFKLKHYG
Sbjct: 185 IGDQKSEDGKELTYKGSQFHRVIKDFMIQGGDFTNGDGTGGRSIYGEKFADENFKLKHYG 6
>15913
          Length = 1796

 Score =  121 bits (304), Expect = 2e-28,   Method: Compositional matrix adjust.
 Identities = 64/139 (46%), Positives = 78/139 (56%), Gaps = 15/139 (10%)
 Frame = -1

Query: 40   PKVTVKVYFDLQIGDESVGRVVFGLFGKTVPKTVDNFVALATGEKG--------FGYKNS 91
            P    + +FD+ IGD+  GR+VF L+    PKT +NF AL TGEKG          YK +
Sbjct: 1754 PGFRPRCFFDVSIGDQPGGRIVFELYSDECPKTCENFRALCTGEKGTSEKTGAVLHYKGA 1575

Query: 92   KFHRVIKDFMIQXXXXXXXXXXXXKSIYGERFPDENFKLKHYGPGWVSMANAGKDTNGSQ 151
             FHRV+KDFM+Q            +SIYG  F DENFK KH     +SMAN GKDTNGSQ
Sbjct: 1574 PFHRVVKDFMVQCGDFTKGDGTGGESIYGGHFADENFKFKHEKECLLSMANRGKDTNGSQ 1395

Query: 152  FFI-------TTVKTSWLD 163
            FFI       T V  +W +
Sbjct: 1394 FFIADRPKLDTAVAGNWCN 1338

 Score = 46.6 bits (109), Expect = 7e-06,   Method: Compositional matrix adjust.
 Identities = 21/53 (39%), Positives = 32/53 (60%)
 Frame = -1

Query: 153 FITTVKTSWLDGKHVVFGKVLEGMDVVRKVESTKTDSRDKPLKDVIIVDSGKI 205
           F     +  LD  HVVFG VL G +VV+K+E   TD+R +P  +V + + G++
Sbjct: 443 FQNNQSSPHLDNVHVVFGHVLSGQEVVKKIEQLPTDARSRPEVEVKVANCGEL 285
>03857
          Length = 1696

 Score =  112 bits (280), Expect = 1e-25,   Method: Compositional matrix adjust.
 Identities = 58/113 (51%), Positives = 74/113 (65%)
 Frame = +1

Query: 96  VIKDFMIQXXXXXXXXXXXXKSIYGERFPDENFKLKHYGPGWVSMANAGKDTNGSQFFIT 155
           VIKDFMIQ            +SIYG++F DE+F  KH  P  +SMANAG +TNGSQFFIT
Sbjct: 13  VIKDFMIQGGDFTNHNGTGGESIYGDKFDDESFDRKHDCPMLLSMANAGPNTNGSQFFIT 192

Query: 156 TVKTSWLDGKHVVFGKVLEGMDVVRKVESTKTDSRDKPLKDVIIVDSGKIEVE 208
           TV T  LDGKHVVFG+V+ G +VVR++E+   D  + P K   I D G++  +
Sbjct: 193 TVPTPHLDGKHVVFGEVIAGHNVVRELENVDKDG-ETPTKTCSIADCGELAAD 348
>05986
          Length = 1295

 Score = 81.3 bits (199), Expect = 3e-16,   Method: Compositional matrix adjust.
 Identities = 48/119 (40%), Positives = 67/119 (56%), Gaps = 1/119 (0%)
 Frame = -3

Query: 56   SVGRVVFGLFGKTVPKTVDNFVALATGEKGFGYKNSKFHRVIKDFMIQXXXXXXXXXXXX 115
            SVG +   L+ K  PK+  NF+ L    +G+ Y  + FHRV+K+F++Q            
Sbjct: 1227 SVGDIDVELWSKEAPKSCRNFIQLCL--EGY-YDGTAFHRVVKEFIVQGGDPTDTGHGG- 1060

Query: 116  KSIYGERFPDE-NFKLKHYGPGWVSMANAGKDTNGSQFFITTVKTSWLDGKHVVFGKVL 173
            +S+YG  F DE + +L+    G V+MANAG   NGSQFF T   T  L  KH +FGKV+
Sbjct: 1059 ESVYGAPFKDEFHSRLRFVRRGLVAMANAGPHDNGSQFFFTMAATPELQNKHTIFGKVV 883
>14547
          Length = 491

 Score = 74.3 bits (181), Expect = 3e-14,   Method: Compositional matrix adjust.
 Identities = 39/95 (41%), Positives = 52/95 (54%), Gaps = 8/95 (8%)
 Frame = -1

Query: 46  VYFDLQIGDESVGRVVFGLFGKTVPKTVDNFVALATGEKG--------FGYKNSKFHRVI 97
           VY D+ IG+E+ GR+V  L+    PKT +NF AL TGEKG          Y NS FHR++
Sbjct: 305 VYMDISIGEEAAGRLVIELYSDKAPKTCENFRALCTGEKGTSEETDLRLXYLNSLFHRIV 126

Query: 98  KDFMIQXXXXXXXXXXXXKSIYGERFPDENFKLKH 132
           ++  IQ            +SI+G  F DENF + H
Sbjct: 125 RNGWIQGGDIYHGRGNGGESIFGTVFEDENFAIPH 21
>02140
          Length = 1796

 Score = 73.2 bits (178), Expect = 7e-14,   Method: Compositional matrix adjust.
 Identities = 51/164 (31%), Positives = 84/164 (51%), Gaps = 8/164 (4%)
 Frame = +3

Query: 56  SVGRVVFGLFGKTVPKTVDNFVALATGEKGFGYKNSKFHRVIKDFMIQXXXXXXXXXXXX 115
           S+G++   L+ +  P+  +NF+ L    K   Y  S FH V ++ + Q            
Sbjct: 105 SIGQLTVDLYTEERPRCSENFLKLC---KVKYYNFSLFHSVQENLVAQTGDPTATGRGGM 275

Query: 116 K---SIYGE--RFPDENF--KLKHYGPGWVSMANAGKDTNGSQFFITTVKT-SWLDGKHV 167
                +YGE  R+ D     ++KH   G +SM N G   +GSQFFIT  ++  +LDG+H 
Sbjct: 276 SVYGMVYGEQARYFDMEVSPRIKHKKRGLLSMVNNGAGKHGSQFFITLGESLDYLDGEHT 455

Query: 168 VFGKVLEGMDVVRKVESTKTDSRDKPLKDVIIVDSGKIEVEKPF 211
           VFG+V EG +V+ K+     D + +P +D+ I  +  + +E P+
Sbjct: 456 VFGEVAEGFEVLDKLNEAYCDEKHRPYRDIRIFHT--VILEDPY 581
>08983
          Length = 430

 Score = 69.7 bits (169), Expect = 8e-13,   Method: Compositional matrix adjust.
 Identities = 34/58 (58%), Positives = 41/58 (70%), Gaps = 1/58 (1%)
 Frame = +3

Query: 118 IYGERFPDE-NFKLKHYGPGWVSMANAGKDTNGSQFFITTVKTSWLDGKHVVFGKVLE 174
           IYG+ F DE    LKH G G +SMAN+G +TNGSQFFIT   T WLDGKH +FG  ++
Sbjct: 132 IYGKNFNDEIADDLKHTGAGILSMANSGPNTNGSQFFITLAPTQWLDGKHSIFGASVQ 305
>23338
          Length = 1062

 Score = 53.5 bits (127), Expect = 7e-08,   Method: Compositional matrix adjust.
 Identities = 31/70 (44%), Positives = 42/70 (60%), Gaps = 1/70 (1%)
 Frame = -1

Query: 146  DTNGSQFFITTVKTSWLDGKHVVFGKVLEGMDVVRKVEST-KTDSRDKPLKDVIIVDSGK 204
            DTNGSQFFIT   + +LDGKHV FGKVL+G  +++ +      D    P + V IVD   
Sbjct: 1062 DTNGSQFFITLGPSRFLDGKHVAFGKVLKGFTLLKTINRMGPGDDYTTPRRPVRIVDC-S 886

Query: 205  IEVEKPFAIA 214
             EV K + ++
Sbjct: 885  TEVVKKYELS 856
>15093
          Length = 537

 Score = 50.1 bits (118), Expect = 6e-07,   Method: Compositional matrix adjust.
 Identities = 22/53 (41%), Positives = 34/53 (64%)
 Frame = +3

Query: 147 TNGSQFFITTVKTSWLDGKHVVFGKVLEGMDVVRKVESTKTDSRDKPLKDVII 199
           TN SQFF T      LDGKH VFG+++ G++ +  +E  + D +DKP +++ I
Sbjct: 3   TNKSQFFFTFRSARHLDGKHAVFGRLVGGIETLDAMEKVEVDKKDKPKEEIKI 161
>21265
          Length = 579

 Score = 40.0 bits (92), Expect = 8e-04,   Method: Compositional matrix adjust.
 Identities = 20/47 (42%), Positives = 27/47 (57%)
 Frame = -3

Query: 56  SVGRVVFGLFGKTVPKTVDNFVALATGEKGFGYKNSKFHRVIKDFMI 102
           ++G +   LF K  PKTV+NF   +   +   + N  FHRVIK FMI
Sbjct: 133 TMGDIQCKLFAKECPKTVENFCVHS---RNSYFNNHVFHRVIKGFMI 2
>27940
          Length = 364

 Score = 28.1 bits (61), Expect = 2.5,   Method: Compositional matrix adjust.
 Identities = 13/33 (39%), Positives = 17/33 (51%), Gaps = 3/33 (9%)
 Frame = -1

Query: 145 KDTNGS---QFFITTVKTSWLDGKHVVFGKVLE 174
           KD N S    F+   V T+W D  H++FG   E
Sbjct: 157 KDLNKSVNNNFYYQMVVTTWCDSSHILFGPNCE 59
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|9625023|ref|NP_062525.1| membrane protein,
palmitoylated 3 (MAGUK p55 subfamily member 5) [Mus musculus]
         (675 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

13641                                                                 251   3e-67
35802                                                                 190   2e-48
27435                                                                 186   3e-47
11512                                                                 134   1e-31
29636                                                                 127   2e-29
33158                                                                 118   7e-27
29974                                                                  94   1e-19
37412                                                                  64   2e-10
08480                                                                  61   1e-09
11574                                                                  49   6e-06
20073                                                                  44   2e-04
17286                                                                  34   0.18 
29687                                                                  33   0.53 
30740                                                                  32   0.61 
01494                                                                  32   0.84 
20495                                                                  32   0.89 
33804                                                                  30   3.0  
02291                                                                  30   3.9  
>13641
          Length = 2081

 Score =  251 bits (640), Expect(2) = 3e-67,   Method: Compositional matrix adjust.
 Identities = 139/363 (38%), Positives = 209/363 (57%), Gaps = 16/363 (4%)
 Frame = +2

Query: 315 NEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQ 374
           N VF + S   G+LT  L+PS++   P +K+  + VKA F ++   D  +PC+E GLSFQ
Sbjct: 62  NAVF-VQSKTSGSLTLKLVPSRRT--PGSKKREMVVKAMFSFNSKLDDNIPCKEAGLSFQ 232

Query: 375 KGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMKQTIEEDKEPEKSGK 434
           +GDILH+++QED  WWQAY+ GD   +  AGL+P + + +++E ++++  ++        
Sbjct: 233 QGDILHIVNQEDAIWWQAYKHGDAKKR--AGLIPSRHYHERQEVLRKSKSKEGRHMARSI 406

Query: 435 LWCAXXXXXXXXXXXXXXXXN-------DDYDNEEILTYEEMSLYHQPANRKRPIILIGP 487
             C                 +        D+D +EI  Y+E+  +       RPI+LIG 
Sbjct: 407 SPCRYSPKVPKQRRLRKTMYHIVQNGALTDFDTDEIPAYDEVEHFTPKPRHFRPIVLIGA 586

Query: 488 QNCGQNELRQRLMNKEKDRFASAVPHTTRNRRDHEVAGRDYHFVSRQAFEADIAAGKFIE 547
              G+NEL++RL       F   VP+TTR ++  E  G++YHFVSR+  E  I A KF+E
Sbjct: 587 PGIGRNELKRRLKASNPMHFLEVVPYTTRTKKPFEEDGKEYHFVSREDMEESIIAQKFVE 766

Query: 548 HGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQERLR- 606
           +GE   +LYGTS++S++QVI +GK+CLL+  TQ+LK LR  +LKPY+IFI  P+ E+L+ 
Sbjct: 767 YGEHHGHLYGTSVESIKQVIAAGKVCLLTPHTQALKFLRTYELKPYVIFIKSPTLEKLKE 946

Query: 607 -----ALLAKEGKNPKP---EELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRL 658
                   A E  + +P   EEL E+ E +R +E+  GH FD  IVN  L  A  ELL +
Sbjct: 947 SRMPARARATEADSIRPFSIEELEEMAETSRRLEERYGHVFDITIVNDSLTDATTELLMV 1126

Query: 659 INK 661
            +K
Sbjct: 1127ASK 1135

 Score = 23.1 bits (48), Expect(2) = 3e-67,   Method: Compositional matrix adjust.
 Identities = 8/13 (61%), Positives = 10/13 (76%)
 Frame = +1

Query: 661  KLDTEPQWVPSTW 673
            K++ EPQWVP  W
Sbjct: 1132 KIEKEPQWVPVGW 1170
>35802
          Length = 571

 Score =  190 bits (482), Expect = 2e-48,   Method: Compositional matrix adjust.
 Identities = 83/154 (53%), Positives = 116/154 (75%), Gaps = 1/154 (0%)
 Frame = +1

Query: 522 EVAGRDYHFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQS 581
           E+ GRDYHF SR  FEAD+ +GKF+E+GEF+ NLYGTS+++VRQVI  G++CLL+L  +S
Sbjct: 1   EMTGRDYHFTSRSMFEADMLSGKFLEYGEFQSNLYGTSVEAVRQVILQGRVCLLNLEPES 180

Query: 582 LKTLRNSDLKPYIIFIAPPSQERLRALLAKEGK-NPKPEELREIIEKTREMEQNNGHYFD 640
           LK LR +DLKPY  F+ PP+ E+LR L    GK  P  ++L+ +++K REME   GH+FD
Sbjct: 181 LKILRETDLKPYTXFVCPPNMEKLRQLHIAMGKIRPTDDQLKTVMDKGREMEDMYGHFFD 360

Query: 641 TAIVNSDLDKAYQELLRLINKLDTEPQWVPSTWL 674
             +VN D+D++ QEL+  IN+++ EPQWVP TW+
Sbjct: 361 YKLVNMDVDRSVQELMAEINRIEVEPQWVPVTWM 462
>27435
          Length = 456

 Score =  186 bits (472), Expect = 3e-47,   Method: Compositional matrix adjust.
 Identities = 82/149 (55%), Positives = 118/149 (79%), Gaps = 1/149 (0%)
 Frame = +1

Query: 525 GRDYHFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKT 584
           G+DYHF++R  FEAD+ +GKF+E+GEF+ NLYGT++++VRQVI  G+IC+L+L  +SLK 
Sbjct: 10  GKDYHFITRAVFEADMLSGKFVEYGEFQGNLYGTTVEAVRQVIQQGRICILNLGPESLKN 189

Query: 585 LRNSDLKPYIIFIAPPSQERLRALLAKEGK-NPKPEELREIIEKTREMEQNNGHYFDTAI 643
           LR ++LKPYIIFI+PP  E+LR L    GK  P  ++++E+IE+ REME+   HYFD  +
Sbjct: 190 LRETELKPYIIFISPPXMEKLRQLQMALGKPRPTDDQVKEVIERGREMEEMYSHYFDYIL 369

Query: 644 VNSDLDKAYQELLRLINKLDTEPQWVPST 672
           VN +L++A+ ELL+ IN+++TEPQWVP T
Sbjct: 370 VNMELNRAFDELLQEINRIETEPQWVPIT 456
>11512
          Length = 1006

 Score =  134 bits (338), Expect = 1e-31,   Method: Compositional matrix adjust.
 Identities = 61/158 (38%), Positives = 101/158 (63%), Gaps = 10/158 (6%)
 Frame = -3

Query: 528  YHFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRN 587
            Y FV+R+  +ADI AGKF+EHGE++ +LYGTS +SV+ ++N+G +C+LS   Q++KTLR 
Sbjct: 1004 YIFVAREKMDADIEAGKFVEHGEYKGHLYGTSAESVKSIVNAGCVCVLSPHYQAIKTLRT 825

Query: 588  SDLKPYIIFIAPPSQERLRALLAK----------EGKNPKPEELREIIEKTREMEQNNGH 637
              LKP++I I PP  + L++   +            ++   EE  ++I+ T  ++   GH
Sbjct: 824  XQLKPFLIHIKPPELDILKSTRTEARAKSTFDEANARSFTDEEFEDMIKSTXRIDFTYGH 645

Query: 638  YFDTAIVNSDLDKAYQELLRLINKLDTEPQWVPSTWLR 675
            +FD  IVN +L  A++ L++ + +L+ EP W PS W++
Sbjct: 644  FFDVEIVNGELLAAFEXLVQHVQRLENEPLWAPSMWVQ 531
>29636
          Length = 354

 Score =  127 bits (318), Expect = 2e-29,   Method: Compositional matrix adjust.
 Identities = 62/115 (53%), Positives = 87/115 (75%), Gaps = 3/115 (2%)
 Frame = +1

Query: 327 TLTFVLIPSQQ-IKPPPAKET-VIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQ 384
           T+TF++IP+   ++   AK   ++H++A F+YDP DDPY+PCRELG+SF KGDILH I  
Sbjct: 1   TITFMIIPAHSCVEDTTAKPGDIMHLRALFNYDPEDDPYIPCRELGISFLKGDILHAIQL 180

Query: 385 EDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMKQTIE-EDKEPEKSGKLWCA 438
            D NWWQA+REG ED   LAGL+P K+FQ+QRE+++Q +  E+KE +K G++ CA
Sbjct: 181 SDSNWWQAHREG-EDAHMLAGLIPSKAFQEQRESVRQQLNAENKENKKRGRI-CA 339
>33158
          Length = 1075

 Score =  118 bits (296), Expect = 7e-27,   Method: Compositional matrix adjust.
 Identities = 81/195 (41%), Positives = 115/195 (58%), Gaps = 17/195 (8%)
 Frame = +2

Query: 124 VEDLFSSLKHIQHTLVD-------SQSQEDISLLLQLVQNRDFQNAFKIHNAVTVHMSKA 176
           VED+ S+L+HI+  L         S  Q+++  L QL  N  FQ    +H  +    S++
Sbjct: 506 VEDVLSTLQHIRTRLSSADNTNDSSTGQQEVHFLKQLFHNPLFQQTVDMHQKMVDVTSRS 685

Query: 177 SPPFPLIANVQDLVQEVQTVLKPVHQKEGQ----ELTALLNAPHIQALLLAHDKVAEQEM 232
             P PL ++ Q+L  +V++    +     +    EL+ LL+ P ++ LL AHD+VA+Q  
Sbjct: 686 PLPRPLGSDSQELACDVKSYGSEMGGSXSEAVVEELSMLLDKPALKNLLKAHDEVADQ-- 859

Query: 233 QLEPITDERVYES------IGHYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKG 286
           Q  PI    V ES      +  YG E+VKI+ +EK  +  LGATV+NE DSV+I+RIVKG
Sbjct: 860 QTHPIL--HVSESDLIDYPLTEYGEESVKIIHLEKTNE-HLGATVKNEGDSVLIARIVKG 1030

Query: 287 GAAEKSGLLHEGDEV 301
           GAAEKSGLLHEGDE+
Sbjct: 1031GAAEKSGLLHEGDEI 1075
>29974
          Length = 344

 Score = 94.4 bits (233), Expect = 1e-19,   Method: Compositional matrix adjust.
 Identities = 47/102 (46%), Positives = 66/102 (64%), Gaps = 1/102 (0%)
 Frame = +1

Query: 499 LMNKEKDRFASAVPHTTRNRRDHEVAGRDYHFVS-RQAFEADIAAGKFIEHGEFEKNLYG 557
           L+++  D+F S +PHTTR RR +E  G+DYHFVS R+  E DI    FIE G +  NLYG
Sbjct: 10  LISEFPDKFGSCIPHTTRERRTNEEPGQDYHFVSSREQMERDIQNHLFIEAGVYNDNLYG 189

Query: 558 TSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAP 599
           TS+ SV++V   G+ C+L +   ++K L+ + L P  IFI P
Sbjct: 190 TSVASVKEVAEQGRHCILDVSGNAIKRLQVAGLYPIAIFIKP 315
>37412
          Length = 757

 Score = 64.3 bits (155), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 42/139 (30%), Positives = 74/139 (53%), Gaps = 14/139 (10%)
 Frame = -1

Query: 533 RQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGK-ICLLSL--------RTQSLK 583
           R   E+DI +G+++E+G+F  NLYGT +D+VRQ+++SG+ +C  S         R  S  
Sbjct: 739 RLTMESDIMSGRYLEYGDFNGNLYGTRLDTVRQIVDSGRCVCWTSTLPH*KSSRRPSSCP 560

Query: 584 TLRNSDLKPYIIFIAPPSQERL-RALLAKEGKNPKPE----ELREIIEKTREMEQNNGHY 638
           TL +S   P + +    S  ++   L A  G   + +       E +++++++E+    Y
Sbjct: 559 TLCSS---PRLAWKLSKSCTKMDDGLHAAAGSVVELK*NGGNFIETMKESQQIERVYASY 389

Query: 639 FDTAIVNSDLDKAYQELLR 657
           FD  IVN   +  Y++L R
Sbjct: 388 FDDIIVNDSFEDTYRQLRR 332
>08480
          Length = 698

 Score = 61.2 bits (147), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 46/163 (28%), Positives = 69/163 (42%), Gaps = 29/163 (17%)
 Frame = -1

Query: 287 GAAEKSGLLHEGDEVLEINGIEI-------------RGKDVNEVF--------------- 318
           G A+ SG L  GD++L +N +++             R  D  E+                
Sbjct: 698 GPADLSGDLRRGDKILSVNDVDVERATHEQAAQALKRAGDTVEIIAQYKPEDYNRFEAKI 519

Query: 319 -DLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGD 377
            DL   M       L  +Q+          + V+A FDY+PS D  +P R  GL F  GD
Sbjct: 518 QDLREQMMNNSAGSLRTTQK--------RTMFVRALFDYEPSKDSGLPSR--GLWFHYGD 369

Query: 378 ILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMK 420
           ILHV +  D  WWQA R   +  +   G++P K   +++E  +
Sbjct: 368 ILHVTNASDDEWWQAKRILPDGKEEGMGIIPSKRRVERKERAR 240
>11574
          Length = 1255

 Score = 48.9 bits (115), Expect = 6e-06,   Method: Compositional matrix adjust.
 Identities = 20/48 (41%), Positives = 32/48 (66%)
 Frame = +2

Query: 627 KTREMEQNNGHYFDTAIVNSDLDKAYQELLRLINKLDTEPQWVPSTWL 674
           + R +E+  GH+FD  IVN+D+D+  + L + I  + T PQWVP +W+
Sbjct: 2   RERAVEKAYGHFFDRQIVNNDIDETIRTLEKAIEDVCTLPQWVPVSWV 145
>20073
          Length = 582

 Score = 43.9 bits (102), Expect = 2e-04,   Method: Composition-based stats.
 Identities = 20/67 (29%), Positives = 38/67 (56%)
 Frame = +3

Query: 272 RNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFV 331
           + +   + ISRI+ GG A++   L  GD++L +NG+ + G+   +  +LL    G++  V
Sbjct: 30  KEQSSPIYISRIIPGGVADRLNCLKRGDQLLSVNGVSVEGEYHEKAVELLKLAQGSVRLV 209

Query: 332 LIPSQQI 338
           +  + QI
Sbjct: 210 VRYTPQI 230
>17286
          Length = 489

 Score = 34.3 bits (77), Expect = 0.18,   Method: Composition-based stats.
 Identities = 22/63 (34%), Positives = 33/63 (52%)
 Frame = +3

Query: 334 PSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAY 393
           P+  +K P A+       A +D+ P  D      ELG  FQ+GD++ +ISQ D NW++  
Sbjct: 3   PTAGVKQPCAR-------AIYDFLPESDG-----ELG--FQEGDMITLISQVDENWFEGS 140

Query: 394 REG 396
             G
Sbjct: 141 VHG 149
>29687
          Length = 434

 Score = 32.7 bits (73), Expect = 0.53,   Method: Compositional matrix adjust.
 Identities = 18/47 (38%), Positives = 25/47 (53%)
 Frame = -2

Query: 346 TVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQA 392
           T + VKA  DY+         RE  LSF KG I+  +S++D  WW+ 
Sbjct: 304 TKLRVKALHDYNAK-------REDELSFCKGAIITNVSRQDGGWWRG 185
>30740
          Length = 488

 Score = 32.3 bits (72), Expect = 0.61,   Method: Compositional matrix adjust.
 Identities = 31/110 (28%), Positives = 50/110 (45%), Gaps = 9/110 (8%)
 Frame = +2

Query: 304 INGIEIRGKDVNEVFDL-LSDMHGTLTFV----LIPSQQIKPPPAKETVIHVKAHFDY-- 356
           IN I++ G    ++ D   +D+   L F     L  +  I+P P ++ +      +D+  
Sbjct: 50  INRIQVGGLTRFKIGDKEFNDIPSLLNFYKSHYLDTTTLIRPAPREKLM----GKYDFSG 217

Query: 357 -DPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAY-REGDEDNQPLA 404
            DP D P          F KGDIL +IS+++  WW A  + G     PL+
Sbjct: 218 RDPEDLP----------FSKGDILELISKDEEEWWTARDKHGRVGQDPLS 337
>01494
          Length = 2122

 Score = 32.0 bits (71), Expect = 0.84,   Method: Compositional matrix adjust.
 Identities = 17/47 (36%), Positives = 26/47 (55%)
 Frame = +3

Query: 346 TVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQA 392
           T + VKA  DY+ +       R+  LSF KG I+  +S++D  WW+ 
Sbjct: 300 TKLRVKALHDYNAN-------RDDELSFCKGAIITNVSRQDGGWWRG 419
>20495
          Length = 859

 Score = 32.0 bits (71), Expect = 0.89,   Method: Compositional matrix adjust.
 Identities = 10/25 (40%), Positives = 18/25 (72%)
 Frame = +2

Query: 650 KAYQELLRLINKLDTEPQWVPSTWL 674
           + Y  +L  IN++++EPQW P+ W+
Sbjct: 521 RTYDVILHEINRIESEPQWTPTAWV 595
>33804
          Length = 621

 Score = 30.0 bits (66), Expect = 3.0,   Method: Composition-based stats.
 Identities = 17/56 (30%), Positives = 27/56 (48%)
 Frame = -1

Query: 616 PKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLINKLDTEPQWVPS 671
           PK   LR+  E+  +MEQ  G YF   +    +++ Y ++  +I        WVPS
Sbjct: 579 PK-SRLRKHFERAIKMEQEFGEYFTGVVQGDTIEEIYSKVKSMIWSQSGPNIWVPS 415
>02291
          Length = 3161

 Score = 29.6 bits (65), Expect = 3.9,   Method: Compositional matrix adjust.
 Identities = 17/40 (42%), Positives = 24/40 (60%)
 Frame = -1

Query: 180  FPLIANVQDLVQEVQTVLKPVHQKEGQELTALLNAPHIQA 219
             P +A ++D V+E   V +PVH   GQE    L+APH+Q 
Sbjct: 1949 IPPVA-IEDRVKEALPVGQPVHADRGQEKVP-LHAPHLQG 1836
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|9845265|ref|NP_063936.1| ubiquitin A-52 residue
ribosomal protein fusion product 1 [Mus musculus]
         (128 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

13455                                                                 248   4e-67
04649                                                                 158   6e-40
04017                                                                 157   1e-39
00758                                                                 156   2e-39
03942                                                                 149   2e-37
34270                                                                 121   1e-30
08296                                                                  97   1e-21
24173                                                                  85   7e-18
02863                                                                  54   5e-17
25295                                                                  50   2e-07
14135                                                                  49   5e-07
13753                                                                  47   2e-06
34268                                                                  46   3e-06
22667                                                                  37   0.003
30505                                                                  28   1.2  
25348                                                                  28   1.3  
19424                                                                  27   2.4  
26463                                                                  27   2.8  
39635                                                                  26   4.3  
36647                                                                  26   5.2  
29288                                                                  25   6.4  
>13455
          Length = 809

 Score =  248 bits (634), Expect = 4e-67,   Method: Compositional matrix adjust.
 Identities = 120/128 (93%), Positives = 124/128 (96%)
 Frame = +3

Query: 1   MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYN 60
           MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYN
Sbjct: 357 MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYN 536

Query: 61  IQKESTLHLVLRLRGGIIEPSLRQLAQKYNCDKMICRKCYARLHPRAVNCRKKKCGHTNN 120
           IQKESTLHLVLRLRGGIIEPSLR LA KYNCDKMICRKCYARLH RA NCRK+KCGHT+N
Sbjct: 537 IQKESTLHLVLRLRGGIIEPSLRILASKYNCDKMICRKCYARLHQRATNCRKRKCGHTSN 716

Query: 121 LRPKKKVK 128
           +RPKKK+K
Sbjct: 717 IRPKKKLK 740
>04649
          Length = 1590

 Score =  158 bits (399), Expect = 6e-40,   Method: Compositional matrix adjust.
 Identities = 76/76 (100%), Positives = 76/76 (100%)
 Frame = -2

Query: 1   MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYN 60
           MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYN
Sbjct: 449 MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYN 270

Query: 61  IQKESTLHLVLRLRGG 76
           IQKESTLHLVLRLRGG
Sbjct: 269 IQKESTLHLVLRLRGG 222
>04017
          Length = 690

 Score =  157 bits (397), Expect = 1e-39,   Method: Compositional matrix adjust.
 Identities = 76/76 (100%), Positives = 76/76 (100%)
 Frame = -1

Query: 1   MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYN 60
           MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYN
Sbjct: 342 MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYN 163

Query: 61  IQKESTLHLVLRLRGG 76
           IQKESTLHLVLRLRGG
Sbjct: 162 IQKESTLHLVLRLRGG 115
>00758
          Length = 1050

 Score =  156 bits (394), Expect = 2e-39,   Method: Compositional matrix adjust.
 Identities = 76/76 (100%), Positives = 76/76 (100%)
 Frame = +1

Query: 1   MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYN 60
           MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYN
Sbjct: 523 MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYN 702

Query: 61  IQKESTLHLVLRLRGG 76
           IQKESTLHLVLRLRGG
Sbjct: 703 IQKESTLHLVLRLRGG 750
>03942
          Length = 912

 Score =  149 bits (377), Expect = 2e-37,   Method: Compositional matrix adjust.
 Identities = 74/76 (97%), Positives = 75/76 (98%)
 Frame = +1

Query: 1   MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYN 60
           MQIFVKTLTGKTITLEVEPSDTIENVKAK +DKEGIPPDQQRLIFAGKQLEDGRTLSDYN
Sbjct: 406 MQIFVKTLTGKTITLEVEPSDTIENVKAKSKDKEGIPPDQQRLIFAGKQLEDGRTLSDYN 585

Query: 61  IQKESTLHLVLRLRGG 76
           IQKESTLHLVLRLRGG
Sbjct: 586 IQKESTLHLVLRLRGG 633
>34270
          Length = 274

 Score =  121 bits (303), Expect(2) = 1e-30,   Method: Compositional matrix adjust.
 Identities = 59/60 (98%), Positives = 59/60 (98%)
 Frame = +1

Query: 6   KTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKES 65
            TLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKES
Sbjct: 49  STLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKES 228

 Score = 27.3 bits (59), Expect(2) = 1e-30,   Method: Compositional matrix adjust.
 Identities = 12/15 (80%), Positives = 13/15 (86%)
 Frame = +2

Query: 62  QKESTLHLVLRLRGG 76
           +K  TLHLVLRLRGG
Sbjct: 218 RKSPTLHLVLRLRGG 262
>08296
          Length = 897

 Score = 97.4 bits (241), Expect = 1e-21,   Method: Compositional matrix adjust.
 Identities = 45/82 (54%), Positives = 62/82 (75%)
 Frame = +1

Query: 1   MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYN 60
           M I VKTLTGK I +++EP+D +E +K ++++KEGIPP QQRLIF+GKQ+ D +T  DY 
Sbjct: 127 MLIKVKTLTGKEIEIDIEPTDKVERIKERVEEKEGIPPQQQRLIFSGKQMNDEKTAQDYK 306

Query: 61  IQKESTLHLVLRLRGGIIEPSL 82
           +   S LHLVL LRGG+  P++
Sbjct: 307 VIGGSVLHLVLALRGGLS*PAV 372
>24173
          Length = 413

 Score = 85.1 bits (209), Expect = 7e-18,   Method: Compositional matrix adjust.
 Identities = 44/72 (61%), Positives = 53/72 (73%), Gaps = 1/72 (1%)
 Frame = -2

Query: 5   VKTLTGKT-ITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQK 63
           +KTLT +    L  E   T+  +K +I DK+GI P+QQRL+FAGKQLEDGR LSDYNI  
Sbjct: 337 LKTLTRQERSALTWEGGVTVGELKCQIYDKDGISPEQQRLVFAGKQLEDGRLLSDYNITD 158

Query: 64  ESTLHLVLRLRG 75
           +STLHLV RLRG
Sbjct: 157 DSTLHLVFRLRG 122
>02863
          Length = 583

 Score = 53.5 bits (127), Expect(2) = 5e-17,   Method: Compositional matrix adjust.
 Identities = 25/46 (54%), Positives = 33/46 (71%)
 Frame = +1

Query: 5   VKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQL 50
           +KTLTGKT+ L  E   T+  +K +I DK+GI P+QQRL+FAGK  
Sbjct: 325 LKTLTGKTVALTGEGGMTVGELKCQIYDKDGISPEQQRLVFAGKHW 462

 Score = 48.9 bits (115), Expect(2) = 5e-17,   Method: Compositional matrix adjust.
 Identities = 23/28 (82%), Positives = 24/28 (85%)
 Frame = +3

Query: 48  KQLEDGRTLSDYNIQKESTLHLVLRLRG 75
           K LEDGR LSDYNI  +STLHLVLRLRG
Sbjct: 453 KTLEDGRLLSDYNITDDSTLHLVLRLRG 536
>25295
          Length = 998

 Score = 50.1 bits (118), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 31/104 (29%), Positives = 53/104 (50%)
 Frame = -2

Query: 8   LTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTL 67
           L G+T+   +  +DTI  +KAK+ +  G+P  +Q+L + G  ++D  TL+ YN    +T+
Sbjct: 964 LNGQTLEFSLPLTDTISVLKAKLNEVLGMPAGKQKLQYEGIFVKDSNTLAFYNFMMGATV 785

Query: 68  HLVLRLRGGIIEPSLRQLAQKYNCDKMICRKCYARLHPRAVNCR 111
            L ++ RGG      R+      C   +C      L+ R VN +
Sbjct: 784 QLQMKERGG------RKK*XLSVCRTALCVVVVVFLYXRRVNGQ 671
>14135
          Length = 567

 Score = 48.9 bits (115), Expect = 5e-07,   Method: Compositional matrix adjust.
 Identities = 24/69 (34%), Positives = 42/69 (60%)
 Frame = +2

Query: 8   LTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTL 67
           L G+T+   +  +DTI  +KAK+ +  G+P  +Q+L + G  ++D  TL+ YN    +T+
Sbjct: 185 LNGQTLEFSLPLTDTISVLKAKLNEVLGMPAGKQKLQYEGIFVKDSNTLAFYNFMMGATV 364

Query: 68  HLVLRLRGG 76
            L ++ RGG
Sbjct: 365 QLQMKERGG 391
>13753
          Length = 812

 Score = 47.0 bits (110), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 28/82 (34%), Positives = 47/82 (57%)
 Frame = -3

Query: 1   MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYN 60
           MQ+FV     +  T+ VE ++T+E+VKA ++++E +  +   + F G  LED   LS   
Sbjct: 498 MQLFVHAQ--QIYTIGVEGAETVEDVKALVEERENVSAEDMAVYFGGSPLEDDVCLS--T 331

Query: 61  IQKESTLHLVLRLRGGIIEPSL 82
           ++  STL +  R+ GG +  SL
Sbjct: 330 LEDLSTLQVEQRMLGGKVHGSL 265
>34268
          Length = 463

 Score = 46.2 bits (108), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 23/25 (92%), Positives = 23/25 (92%)
 Frame = -2

Query: 1  MQIFVKTLTGKTITLEVEPSDTIEN 25
          MQIFVKTLT KTITLEVEP DTIEN
Sbjct: 96 MQIFVKTLTCKTITLEVEPMDTIEN 22
>22667
          Length = 1002

 Score = 36.6 bits (83), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 17/17 (100%), Positives = 17/17 (100%)
 Frame = +3

Query: 61  IQKESTLHLVLRLRGGI 77
           IQKESTLHLVLRLRGGI
Sbjct: 450 IQKESTLHLVLRLRGGI 500
>30505
          Length = 549

 Score = 27.7 bits (60), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 10/31 (32%), Positives = 20/31 (64%)
 Frame = -3

Query: 68  HLVLRLRGGIIEPSLRQLAQKYNCDKMICRK 98
           H V+ L+  ++   ++  AQ +NC+ ++CRK
Sbjct: 151 HCVVHLQPWLVLNRIQGSAQDFNCESLLCRK 59
>25348
          Length = 686

 Score = 27.7 bits (60), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 11/23 (47%), Positives = 15/23 (65%)
 Frame = +3

Query: 54  RTLSDYNIQKESTLHLVLRLRGG 76
           R L +Y ++ E  L  VLR+RGG
Sbjct: 456 RKLGNYYVEAEPKLAFVLRIRGG 524
>19424
          Length = 449

 Score = 26.9 bits (58), Expect = 2.4,   Method: Compositional matrix adjust.
 Identities = 11/24 (45%), Positives = 15/24 (62%)
 Frame = -3

Query: 91  CDKMICRKCYARLHPRAVNCRKKK 114
           C +M+CR C+ RLH R + C   K
Sbjct: 399 CSEMVCR-CHVRLHSRLILCMSGK 331
>26463
          Length = 756

 Score = 26.6 bits (57), Expect = 2.8,   Method: Compositional matrix adjust.
 Identities = 9/21 (42%), Positives = 13/21 (61%)
 Frame = -2

Query: 89  YNCDKMICRKCYARLHPRAVN 109
           Y C + +CR C+  LHP + N
Sbjct: 335 YQCQQPLCRHCHCFLHPASSN 273
>39635
          Length = 897

 Score = 26.2 bits (56), Expect = 4.3,   Method: Compositional matrix adjust.
 Identities = 17/61 (27%), Positives = 30/61 (49%), Gaps = 1/61 (1%)
 Frame = +3

Query: 53  GRTLSDYNIQKESTLHLVLRLRG-GIIEPSLRQLAQKYNCDKMICRKCYARLHPRAVNCR 111
            R L +Y ++ E  L  VLR+RG   + P  R++ Q +   + I    + +L+   +N  
Sbjct: 228 ARKLGNYYVEAEPKLAFVLRIRGINGVHPRPRKVLQLFRL-RQINNGVFIKLNRATLNML 404

Query: 112 K 112
           K
Sbjct: 405 K 407
>36647
          Length = 500

 Score = 25.8 bits (55), Expect = 5.2,   Method: Compositional matrix adjust.
 Identities = 11/29 (37%), Positives = 17/29 (58%)
 Frame = -2

Query: 78  IEPSLRQLAQKYNCDKMICRKCYARLHPR 106
           +  +LR+L ++Y C     RK + RLH R
Sbjct: 196 VTHALRKLHKRYTCVTRALRKLHIRLHMR 110
>29288
          Length = 421

 Score = 25.4 bits (54), Expect = 6.4,   Method: Compositional matrix adjust.
 Identities = 8/24 (33%), Positives = 17/24 (70%)
 Frame = -3

Query: 91  CDKMICRKCYARLHPRAVNCRKKK 114
           CD ++CR C+ ++H  +++ RK +
Sbjct: 101 CDTVMCRSCFDKVHQISISLRKHQ 30
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|39841057|ref|NP_950197.1| centrosomal protein 135
[Mus musculus]
         (1140 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

04618                                                                 249   6e-67
16755                                                                  41   0.003
21384                                                                  35   0.13 
05701                                                                  34   0.32 
12149                                                                  31   2.4  
09902                                                                  31   2.5  
17207                                                                  30   3.8  
02408                                                                  30   5.0  
15526                                                                  30   5.3  
>04618
          Length = 1663

 Score =  249 bits (635), Expect(2) = 6e-67,   Method: Compositional matrix adjust.
 Identities = 137/342 (40%), Positives = 227/342 (66%)
 Frame = -3

Query: 762  KVIAQLKVTVAEYETSLNQLQETLTTRDREINSLRRQLDASHKELDDVGKSREISFKENR 821
            +V++ LKV V E +  L+   + L  +DREI SLRRQ+++ +++L +  + R+I  +ENR
Sbjct: 1661 RVVSDLKVRVGELDAQLHHANDNLCLKDREIKSLRRQVESVNEDLGEASRGRDICVQENR 1482

Query: 822  RLQDDLATMARENQEISLELEAAVQEKEEMKSRVHKYITEVSRWESLMAAKEKENKDLLD 881
            RLQDDL   A+ENQ+++ EL+ A+ E+E +K +V KYI EV R E ++A KE E  DLL+
Sbjct: 1481 RLQDDLTVTAKENQKLNAELQDALAEREALKDQVQKYILEVRRVEDMLANKEAERSDLLE 1302

Query: 882  RFQMLHSRAEDWEVKAQQAEGENSSVRLELLSIDTERRHLRERVDLLEKEIQEHINAHHA 941
            +++ L   AE ++  + Q E E S++RLE+++ ++E R   +++D LE+EIQEH+ +  A
Sbjct: 1301 QYRKLSLEAEQFQTTSHQLESEGSNMRLEIMTKESELRRAHDKLDNLEREIQEHVQSQQA 1122

Query: 942  YESQISSMAKAMSQLEEELRRHESEKATMLGDVSSLRELCIKLDSGKDVMTQQLNSKSLE 1001
            YE Q+ S+ ++++ LEE LR+ E EK+ +  D +S RE   +LD  K+ + ++L +  LE
Sbjct: 1121 YEQQVVSLTRSVTTLEESLRQAEDEKSVLRADYTSSRESATQLDGQKEQLQRRLAALQLE 942

Query: 1002 LERAVAELENVKSESELLKKQLTNERQTIKNLESLLATNRDKEFQSHLTSHEKDTEIQXX 1061
             E+  + +E+++ ESE L+ Q++ ER T+KNLE+LL   R+KEFQ+ L+S E++TEIQ  
Sbjct: 941  KEQLHSLVEDLRQESECLQDQVSQERSTVKNLEALLQNGREKEFQNQLSSQERNTEIQML 762

Query: 1062 XXXXXXXXXXXTTQSRETSMLRTKVTQLQTDYDNLKRQMSNE 1103
                        +Q+RE +  RT+  +L+ D + L+RQ++NE
Sbjct: 761  KDRLSLNESKLQSQAREVASFRTRNVELEGDIERLRRQLTNE 636

 Score = 25.4 bits (54), Expect(2) = 6e-67,   Method: Compositional matrix adjust.
 Identities = 9/13 (69%), Positives = 13/13 (100%)
 Frame = -2

Query: 1104 KYERERAIQEMRR 1116
            ++ERERA+QE+RR
Sbjct: 636  RFERERAVQELRR 598
>16755
          Length = 426

 Score = 40.8 bits (94), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 30/96 (31%), Positives = 60/96 (62%), Gaps = 4/96 (4%)
 Frame = +3

Query: 316 CQELTEIDQLAQRLERHKEQVLETADKELGEAKKEIKRNLCEMRNLEEKMSKLQWELDLS 375
           CQ L  +D++A +L+  K+ V+  AD+E+GEAK E++++  E+ +L+  +S+L+ E    
Sbjct: 93  CQ-LQNVDRVAAKLQTDKDVVVRAADREMGEAKTELEKSRHELEDLDNLVSQLRAENKRM 269

Query: 376 HKEKERLNSELLLKS----DLETVVHQLEQEKQRLS 407
            K+   + + L ++      LE ++ + ++EK+RLS
Sbjct: 270 EKDFSDMKARLAVREADNRKLEDLLDRXQEEKKRLS 377
>21384
          Length = 684

 Score = 35.4 bits (80), Expect = 0.13,   Method: Compositional matrix adjust.
 Identities = 42/185 (22%), Positives = 78/185 (42%), Gaps = 24/185 (12%)
 Frame = +1

Query: 643 NKSKLQAQKLSHVTGDSSHQKTEMTSLRIVSE--QLQRSLDDCQHRLSIKRGELESAQEQ 700
           N +  +A  LS   GD+  +     +  ++SE   +   +D    RL  +    E  Q  
Sbjct: 55  NTASAKASNLSCSLGDARWRMAAEGNTNLLSELRGMLYDMDGEIQRLRTRVSTQEDDQRA 234

Query: 701 IKMLEQKLENLSHRMTVQSEETHAMKKTIGVMDKEKDFLQETVDEKTEKIANLQESLLSK 760
           ++ L  +L +L H+  +  +    ++K IG ++ +K  L   + +  E++ +    LL+ 
Sbjct: 235 VRDLRSELTSLMHKADIGEKHVRELEKVIGKLEADKTSLARQLAQHXEELGSRDSQLLAV 414

Query: 761 EKVIAQLKVTVAEYE---------------------TSLNQLQETLTTRDREINSLRRQL 799
           E  +AQ    + E +                      +++Q +  L  R  E+NSLR QL
Sbjct: 415 ESRLAQRNTQIIELQEDGNRRCEEIARLEKEVWRKSATVSQCEAQLEERGDEVNSLRSQL 594

Query: 800 -DASH 803
             ASH
Sbjct: 595 TQASH 609
>05701
          Length = 492

 Score = 34.3 bits (77), Expect = 0.32,   Method: Composition-based stats.
 Identities = 16/41 (39%), Positives = 21/41 (51%), Gaps = 1/41 (2%)
 Frame = -3

Query: 155 QTPGGRKRNIAF-RRQRMQIDEPAPPSEVSAYPVPQPEDPY 194
           QTPGGRKRN+    +Q + I     P   S +  P P  P+
Sbjct: 421 QTPGGRKRNLKLCFQQSISIITEIVPHHFSEFSPPMPAQPF 299
>12149
          Length = 576

 Score = 31.2 bits (69), Expect = 2.4,   Method: Compositional matrix adjust.
 Identities = 23/87 (26%), Positives = 40/87 (45%), Gaps = 3/87 (3%)
 Frame = +3

Query: 557 STSPNHLVSCVEKEKERALSELRRITAE---KEALREKLKNIQERNAVGKSDLEKTIEHL 613
             +  HL+  +   K       RR  A+      L+E L+ +  ++      L+K  +HL
Sbjct: 96  GYAGKHLIKLLVSRKWGGKQGSRRAAADTVTGMTLQESLQILNLKSVDDLEGLQKNYDHL 275

Query: 614 TYINHQLENEKYELQSKMLMMKETVES 640
             +N + +   + LQSK+L  KE +ES
Sbjct: 276 FAVNEKAKGGSFYLQSKVLRAKERIES 356
>09902
          Length = 1917

 Score = 31.2 bits (69), Expect = 2.5,   Method: Compositional matrix adjust.
 Identities = 26/97 (26%), Positives = 41/97 (42%), Gaps = 5/97 (5%)
 Frame = +2

Query: 661 HQKTEMTSLRIVSEQLQRSLDDCQHRLSIKRGELESAQEQIKMLEQKLE-----NLSHRM 715
           + KT +    +VSE     L DC  ++ I+R  L    E+++ L + LE     + S   
Sbjct: 497 YLKTRLRIQHVVSETPPSFLRDCSQKVCIERKPLRFCSERLQSLMRTLELTDLKDYSALS 676

Query: 716 TVQSEETHAMKKTIGVMDKEKDFLQETVDEKTEKIAN 752
            V    T     T G M      + E  D++T  I+N
Sbjct: 677 LVSGFATLVSTYTKGFM-----LIMEPFDDRTPTISN 772
>17207
          Length = 567

 Score = 30.4 bits (67), Expect = 3.8,   Method: Compositional matrix adjust.
 Identities = 14/36 (38%), Positives = 22/36 (61%)
 Frame = +3

Query: 605 DLEKTIEHLTYINHQLENEKYELQSKMLMMKETVES 640
            L+K  +HL  +N + +   + LQSK+L  KE +ES
Sbjct: 243 GLQKNYDHLFAVNEKAKGGSFYLQSKVLRAKERIES 350
>02408
          Length = 1773

 Score = 30.0 bits (66), Expect = 5.0,   Method: Composition-based stats.
 Identities = 19/66 (28%), Positives = 33/66 (50%), Gaps = 2/66 (3%)
 Frame = -3

Query: 929  EKEIQE-HINAHHAYES-QISSMAKAMSQLEEELRRHESEKATMLGDVSSLRELCIKLDS 986
            EKE QE H  AH  +   +++++ +   +     R H+  +    G     RELC+K DS
Sbjct: 1675 EKEAQEEHQRAHPDHRHHRVTNVGEVRREFSATSRCHQGGRDPENGGTDRARELCLKYDS 1496

Query: 987  GKDVMT 992
             +++ T
Sbjct: 1495 TRNLTT 1478
>15526
          Length = 869

 Score = 30.0 bits (66), Expect = 5.3,   Method: Compositional matrix adjust.
 Identities = 14/36 (38%), Positives = 22/36 (61%)
 Frame = +3

Query: 605 DLEKTIEHLTYINHQLENEKYELQSKMLMMKETVES 640
            L+K  +HL  +N + +   + LQSK+L  KE +ES
Sbjct: 543 GLQKNYDHLFAVNEKAKGGSFYLQSKVLRAKERIES 650
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|40254642|ref|NP_031888.2| discs large homolog 1 [Mus
musculus]
         (927 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

08480                                                                 252   6e-67
29974                                                                 180   2e-45
13641                                                                 147   2e-35
29705                                                                 110   2e-24
33804                                                                  82   2e-20
27435                                                                  94   2e-19
35802                                                                  84   3e-16
11512                                                                  77   3e-14
29636                                                                  59   6e-09
20073                                                                  57   4e-08
03499                                                                  50   6e-06
26154                                                                  49   1e-05
03831                                                                  48   2e-05
27345                                                                  47   3e-05
39267                                                                  43   7e-04
38751                                                                  38   0.023
01502                                                                  35   0.15 
02951                                                                  35   0.17 
37412                                                                  34   0.26 
37239                                                                  34   0.27 
30740                                                                  33   0.67 
12324                                                                  32   1.1  
30747                                                                  32   1.2  
33158                                                                  29   6.9  
14655                                                                  29   9.0  
>08480
          Length = 698

 Score =  252 bits (643), Expect = 6e-67,   Method: Compositional matrix adjust.
 Identities = 132/239 (55%), Positives = 165/239 (69%)
 Frame = -1

Query: 498 GPADLSGELRKGDRIISVNSVDLRAASHEQXXXXXXXXXXXVTIVAQYRPEEYSRFEAKI 557
           GPADLSG+LR+GD+I+SVN VD+  A+HEQ           V I+AQY+PE+Y+RFEAKI
Sbjct: 698 GPADLSGDLRRGDKILSVNDVDVERATHEQAAQALKRAGDTVEIIAQYKPEDYNRFEAKI 519

Query: 558 HDLREQMMNXXXXXXXXXLRTSQKRSLYVRALFDYDKTKDSGLPSQGLNFRFGDILHVIN 617
            DLREQMMN         LRT+QKR+++VRALFDY+ +KDSGLPS+GL F +GDILHV N
Sbjct: 518 QDLREQMMNNSAGS----LRTTQKRTMFVRALFDYEPSKDSGLPSRGLWFHYGDILHVTN 351

Query: 618 ASDDEWWQARQVTPDGESDEVGVIPSKRRVEKKERARLKTVKFNSKTRGDKGQSFNDKRK 677
           ASDDEWWQA+++ PDG+ + +G+IPSKRRVE+KERARL+ VKF   +        +  +K
Sbjct: 350 ASDDEWWQAKRILPDGKEEGMGIIPSKRRVERKERARLRNVKFGKNSTSTDKPVKDKGKK 171

Query: 678 KNLFSRKFPFYKNKDQSEQETSDADQHVTSNASDSESSYRGQEEYVLSYEPVNQQEVNY 736
           K+   R FPF K KDQS  E    D+    N      S RG EE VLSYE V QQE+ Y
Sbjct: 170 KS--GRMFPFKKGKDQSGSEDVSGDEVEEGNLPSDSDSNRG-EEPVLSYETVTQQELKY 3

 Score = 42.7 bits (99), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 21/42 (50%), Positives = 26/42 (61%)
 Frame = -1

Query: 357 GAAHKDGKLQIGDKLLAVNSVCLEEVTHEEAVTALKNTSDFV 398
           G A   G L+ GDK+L+VN V +E  THE+A  ALK   D V
Sbjct: 698 GPADLSGDLRRGDKILSVNDVDVERATHEQAAQALKRAGDTV 573

 Score = 41.6 bits (96), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 25/61 (40%), Positives = 32/61 (52%)
 Frame = -1

Query: 262 GAAAQDGRLRVNDCILRVNEADVRDVTHSKAVEALKEAGSIVRLYVKRRKPASEKIMEIK 321
           G A   G LR  D IL VN+ DV   TH +A +ALK AG  V + + + KP      E K
Sbjct: 698 GPADLSGDLRRGDKILSVNDVDVERATHEQAAQALKRAGDTVEI-IAQYKPEDYNRFEAK 522

Query: 322 L 322
           +
Sbjct: 521 I 519
>29974
          Length = 344

 Score =  180 bits (457), Expect = 2e-45,   Method: Compositional matrix adjust.
 Identities = 82/108 (75%), Positives = 95/108 (87%)
 Frame = +1

Query: 751 NDDLISEFPDKFGSCVPHTTRPKRDYEVDGRDYHFVTSREQMEKDIQEHKFIEAGQYNNH 810
           NDDLISEFPDKFGSC+PHTTR +R  E  G+DYHFV+SREQME+DIQ H FIEAG YN++
Sbjct: 1   NDDLISEFPDKFGSCIPHTTRERRTNEEPGQDYHFVSSREQMERDIQNHLFIEAGVYNDN 180

Query: 811 LYGTSVQSVRAVAEKGKHCILDVSGNAIKRLQIAQLYPISIFIKPKSM 858
           LYGTSV SV+ VAE+G+HCILDVSGNAIKRLQ+A LYPI+IFIKP  +
Sbjct: 181 LYGTSVASVKEVAEQGRHCILDVSGNAIKRLQVAGLYPIAIFIKPSRL 324
>13641
          Length = 2081

 Score =  147 bits (371), Expect = 2e-35,   Method: Compositional matrix adjust.
 Identities = 103/345 (29%), Positives = 176/345 (51%), Gaps = 21/345 (6%)
 Frame = +2

Query: 579 SQKRSLYVRALFDYDKTKDSGLPSQ--GLNFRFGDILHVINASDDEWWQARQVTPDGESD 636
           S+KR + V+A+F ++   D  +P +  GL+F+ GDILH++N  D  WWQA +    G++ 
Sbjct: 137 SKKREMVVKAMFSFNSKLDDNIPCKEAGLSFQQGDILHIVNQEDAIWWQAYK---HGDAK 307

Query: 637 E-VGVIPSKRRVEKKERARLKTVKFNSKTRGDKGQSFNDKRKKNLFSRKFPFYKNKDQSE 695
           +  G+IPS+   E++E  R        K++  +G+          +S K P        +
Sbjct: 308 KRAGLIPSRHYHERQEVLR--------KSKSKEGRHMARSISPCRYSPKVP-------KQ 442

Query: 696 QETSDADQHVTSNASDSESSYRGQEEYVLSYEPVNQ--QEVNYTRPVIILGP---MKDRV 750
           +       H+  N + ++       + + +Y+ V     +  + RP++++G     ++ +
Sbjct: 443 RRLRKTMYHIVQNGALTDFD----TDEIPAYDEVEHFTPKPRHFRPIVLIGAPGIGRNEL 610

Query: 751 NDDLISEFPDKFGSCVPHTTRPKRDYEVDGRDYHFVTSREQMEKDIQEHKFIEAGQYNNH 810
              L +  P  F   VP+TTR K+ +E DG++YHFV SRE ME+ I   KF+E G+++ H
Sbjct: 611 KRRLKASNPMHFLEVVPYTTRTKKPFEEDGKEYHFV-SREDMEESIIAQKFVEYGEHHGH 787

Query: 811 LYGTSVQSVRAVAEKGKHCILDVSGNAIKRLQIAQLYPISIFIKPKSMENI----MEMNK 866
           LYGTSV+S++ V   GK C+L     A+K L+  +L P  IFIK  ++E +    M    
Sbjct: 788 LYGTSVESIKQVIAAGKVCLLTPHTQALKFLRTYELKPYVIFIKSPTLEKLKESRMPARA 967

Query: 867 RLTEEQARKTF---------ERAMKLEQEFTEHFTAIVQGDTLED 902
           R TE  + + F         E + +LE+ +   F   +  D+L D
Sbjct: 968 RATEADSIRPFSIEELEEMAETSRRLEERYGHVFDITIVNDSLTD 1102
>29705
          Length = 674

 Score =  110 bits (276), Expect = 2e-24,   Method: Compositional matrix adjust.
 Identities = 72/188 (38%), Positives = 100/188 (53%), Gaps = 19/188 (10%)
 Frame = -1

Query: 244 NPHIGDDSSIFITKIITGGAAAQDGRLRVNDCILRVNEADVRDVTHSKAVEALKEAGSIV 303
           NPHIGDD SI+ITK+I  G            C  R   ++  +  H ++    +     V
Sbjct: 674 NPHIGDDPSIYITKLIPRG------------CCCRGWPSET-ERHHCQSGH*RR-----V 549

Query: 304 RLYVKRRKPASEKIMEIKLIKGP-------------------KGLGFSIAGGVGNQHIPG 344
           + +  RR+   + + +  L+                      +G G     G GNQHIPG
Sbjct: 548 QHHSHRRR*CPQTLRQQSLLASETAEDSDRKSHRHRPGQGS*QGSGIQHCRGKGNQHIPG 369

Query: 345 DNSIYVTKIIEGGAAHKDGKLQIGDKLLAVNSVCLEEVTHEEAVTALKNTSDFVYLKVAK 404
           DN I++TK+IEGG+A +DG++ + D+LLAVN   LE+VTHEEAV ALK+T D V L +AK
Sbjct: 368 DNGIFITKVIEGGSAEQDGRIAVMDRLLAVNEHNLEDVTHEEAVAALKSTGDVVRLTIAK 189

Query: 405 PTSMYIND 412
           PT  YI D
Sbjct: 188 PT--YIAD 171

 Score = 77.8 bits (190), Expect = 2e-14,   Method: Compositional matrix adjust.
 Identities = 39/77 (50%), Positives = 50/77 (64%)
 Frame = -1

Query: 233 GLGFSIAGGTDNPHIGDDSSIFITKIITGGAAAQDGRLRVNDCILRVNEADVRDVTHSKA 292
           G G     G  N HI  D+ IFITK+I GG+A QDGR+ V D +L VNE ++ DVTH +A
Sbjct: 419 GSGIQHCRGKGNQHIPGDNGIFITKVIEGGSAEQDGRIAVMDRLLAVNEHNLEDVTHEEA 240

Query: 293 VEALKEAGSIVRLYVKR 309
           V ALK  G +VRL + +
Sbjct: 239 VAALKSTGDVVRLTIAK 189

 Score = 35.0 bits (79), Expect = 0.14,   Method: Compositional matrix adjust.
 Identities = 15/40 (37%), Positives = 26/40 (65%)
 Frame = -1

Query: 488 GIFISFILAGGPADLSGELRKGDRIISVNSVDLRAASHEQ 527
           GIFI+ ++ GG A+  G +   DR+++VN  +L   +HE+
Sbjct: 362 GIFITKVIEGGSAEQDGRIAVMDRLLAVNEHNLEDVTHEE 243
>33804
          Length = 621

 Score = 82.0 bits (201), Expect(2) = 2e-20,   Method: Compositional matrix adjust.
 Identities = 36/54 (66%), Positives = 46/54 (85%)
 Frame = -1

Query: 874 RKTFERAMKLEQEFTEHFTAIVQGDTLEDIYNQVKQIIEEQSGPYIWVPAKEKL 927
           RK FERA+K+EQEF E+FT +VQGDT+E+IY++VK +I  QSGP IWVP+KE L
Sbjct: 564 RKHFERAIKMEQEFGEYFTGVVQGDTIEEIYSKVKSMIWSQSGPNIWVPSKESL 403

 Score = 35.8 bits (81), Expect(2) = 2e-20,   Method: Composition-based stats.
 Identities = 15/22 (68%), Positives = 22/22 (100%)
 Frame = -3

Query: 856 KSMENIMEMNKRLTEEQARKTF 877
           KS++++MEMN+R+TEEQA+KTF
Sbjct: 619 KSVDSVMEMNRRMTEEQAKKTF 554
>27435
          Length = 456

 Score = 94.4 bits (233), Expect = 2e-19,   Method: Compositional matrix adjust.
 Identities = 50/151 (33%), Positives = 88/151 (58%), Gaps = 5/151 (3%)
 Frame = +1

Query: 777 EVDGRDYHFVTSREQMEKDIQEHKFIEAGQYNNHLYGTSVQSVRAVAEKGKHCILDVSGN 836
           E +G+DYHF+T R   E D+   KF+E G++  +LYGT+V++VR V ++G+ CIL++   
Sbjct: 1   EHNGKDYHFIT-RAVFEADMLSGKFVEYGEFQGNLYGTTVEAVRQVIQQGRICILNLGPE 177

Query: 837 AIKRLQIAQLYPISIFIKPKSMENIMEMNKRL-----TEEQARKTFERAMKLEQEFTEHF 891
           ++K L+  +L P  IFI P  ME + ++   L     T++Q ++  ER  ++E+ ++ +F
Sbjct: 178 SLKNLRETELKPYIIFISPPXMEKLRQLQMALGKPRPTDDQVKEVIERGREMEEMYSHYF 357

Query: 892 TAIVQGDTLEDIYNQVKQIIEEQSGPYIWVP 922
             I+    L   ++++ Q I        WVP
Sbjct: 358 DYILVNMELNRAFDELLQEINRIETEPQWVP 450
>35802
          Length = 571

 Score = 84.0 bits (206), Expect = 3e-16,   Method: Compositional matrix adjust.
 Identities = 48/155 (30%), Positives = 91/155 (58%), Gaps = 10/155 (6%)
 Frame = +1

Query: 777 EVDGRDYHFVTSREQMEKDIQEHKFIEAGQYNNHLYGTSVQSVRAVAEKGKHCILDVSGN 836
           E+ GRDYHF TSR   E D+   KF+E G++ ++LYGTSV++VR V  +G+ C+L++   
Sbjct: 1   EMTGRDYHF-TSRSMFEADMLSGKFLEYGEFQSNLYGTSVEAVRQVILQGRVCLLNLEPE 177

Query: 837 AIKRLQIAQLYPISIFIKPKSMENIMEMN-----KRLTEEQARKTFERAMKLEQEFTEHF 891
           ++K L+   L P + F+ P +ME + +++      R T++Q +   ++  ++E  +   F
Sbjct: 178 SLKILRETDLKPYTXFVCPPNMEKLRQLHIAMGKIRPTDDQLKTVMDKGREMEDMYGHFF 357

Query: 892 -TAIVQGD---TLEDIYNQVKQI-IEEQSGPYIWV 921
              +V  D   +++++  ++ +I +E Q  P  W+
Sbjct: 358 DYKLVNMDVDRSVQELMAEINRIEVEPQWVPVTWM 462
>11512
          Length = 1006

 Score = 77.0 bits (188), Expect = 3e-14,   Method: Compositional matrix adjust.
 Identities = 54/159 (33%), Positives = 84/159 (52%), Gaps = 18/159 (11%)
 Frame = -3

Query: 783  YHFVTSREQMEKDIQEHKFIEAGQYNNHLYGTSVQSVRAVAEKGKHCILDVSGNAIKRLQ 842
            Y FV +RE+M+ DI+  KF+E G+Y  HLYGTS +SV+++   G  C+L     AIK L+
Sbjct: 1004 YIFV-AREKMDADIEAGKFVEHGEYKGHLYGTSAESVKSIVNAGCVCVLSPHYQAIKTLR 828

Query: 843  IAQLYPISIFIKPKSMENIMEMNKRLTEEQARKTFERAMK---LEQEFTE---------- 889
              QL P  I IKP  + +I++  +  TE +A+ TF+ A      ++EF +          
Sbjct: 827  TXQLKPFLIHIKPPEL-DILKSTR--TEARAKSTFDEANARSFTDEEFEDMIKSTXRIDF 657

Query: 890  ---HF--TAIVQGDTLEDIYNQVKQIIEEQSGPYIWVPA 923
               HF    IV G+ L      V+ +   ++ P +W P+
Sbjct: 656  TYGHFFDVEIVNGELLAAFEXLVQHVQRLENEP-LWAPS 543
>29636
          Length = 354

 Score = 59.3 bits (142), Expect = 6e-09,   Method: Composition-based stats.
 Identities = 36/89 (40%), Positives = 52/89 (58%), Gaps = 6/89 (6%)
 Frame = +1

Query: 584 LYVRALFDYDKTKDSGLPSQ--GLNFRFGDILHVINASDDEWWQARQVTPDGESDEV--G 639
           +++RALF+YD   D  +P +  G++F  GDILH I  SD  WWQA +   +GE   +  G
Sbjct: 70  MHLRALFNYDPEDDPYIPCRELGISFLKGDILHAIQLSDSNWWQAHR---EGEDAHMLAG 240

Query: 640 VIPSKRRVEKKE--RARLKTVKFNSKTRG 666
           +IPSK   E++E  R +L      +K RG
Sbjct: 241 LIPSKAFQEQRESVRQQLNAENKENKKRG 327
>20073
          Length = 582

 Score = 57.0 bits (136), Expect = 4e-08,   Method: Compositional matrix adjust.
 Identities = 31/83 (37%), Positives = 46/83 (55%), Gaps = 1/83 (1%)
 Frame = +3

Query: 475 GLGFNIVGG-EDGEGIFISFILAGGPADLSGELRKGDRIISVNSVDLRAASHEQXXXXXX 533
           GLGFN++GG E    I+IS I+ GG AD    L++GD+++SVN V +    HE+      
Sbjct: 3   GLGFNVMGGKEQSSPIYISRIIPGGVADRLNCLKRGDQLLSVNGVSVEGEYHEKAVELLK 182

Query: 534 XXXXXVTIVAQYRPEEYSRFEAK 556
                V +V +Y P+     EA+
Sbjct: 183 LAQGSVRLVVRYTPQILEEMEAR 251

 Score = 50.4 bits (119), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 32/76 (42%), Positives = 42/76 (55%)
 Frame = +3

Query: 233 GLGFSIAGGTDNPHIGDDSSIFITKIITGGAAAQDGRLRVNDCILRVNEADVRDVTHSKA 292
           GLGF++ GG +       S I+I++II GG A +   L+  D +L VN   V    H KA
Sbjct: 3   GLGFNVMGGKE-----QSSPIYISRIIPGGVADRLNCLKRGDQLLSVNGVSVEGEYHEKA 167

Query: 293 VEALKEAGSIVRLYVK 308
           VE LK A   VRL V+
Sbjct: 168 VELLKLAQGSVRLVVR 215

 Score = 49.7 bits (117), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 33/75 (44%), Positives = 44/75 (58%)
 Frame = +3

Query: 328 GLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGKLQIGDKLLAVNSVCLEEVTHEEA 387
           GLGF++ GG   Q  P    IY+++II GG A +   L+ GD+LL+VN V +E   HE+A
Sbjct: 3   GLGFNVMGG-KEQSSP----IYISRIIPGGVADRLNCLKRGDQLLSVNGVSVEGEYHEKA 167

Query: 388 VTALKNTSDFVYLKV 402
           V  LK     V L V
Sbjct: 168 VELLKLAQGSVRLVV 212
>03499
          Length = 1247

 Score = 49.7 bits (117), Expect = 6e-06,   Method: Compositional matrix adjust.
 Identities = 25/91 (27%), Positives = 49/91 (53%)
 Frame = -3

Query: 305  LYVKRRKPASEKIMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGK 364
             + K+      + ++  L+K  +G GF+I   VG+ H P    + +  ++  G A+ +GK
Sbjct: 1017 FFTKQPGELQGEFVKTSLVKSVRGFGFTI---VGSDH-PDTEFLQIKNVVPNGPAYLNGK 850

Query: 365  LQIGDKLLAVNSVCLEEVTHEEAVTALKNTS 395
            L+ GD ++ VN+ C+   TH++ V+  +  S
Sbjct: 849  LKTGDVIVFVNTTCVLGYTHQDVVSLFQTIS 757
>26154
          Length = 446

 Score = 48.5 bits (114), Expect = 1e-05,   Method: Composition-based stats.
 Identities = 46/161 (28%), Positives = 66/161 (40%), Gaps = 1/161 (0%)
 Frame = -3

Query: 357 GAAHKDGKLQIGDKLLAVNSVCLEEVTHEEAVTALKNTSDFVYLKVAKPTSMYINDGYAP 416
           G+AH+ G +Q GDKL+A+N V L+  T ++A   L+   + V LKV +            
Sbjct: 408 GSAHRCGSIQAGDKLMAINDVRLDTCTVDDATHLLELPDELVKLKVQRDD---------- 259

Query: 417 PDITNSSSQSVDNHVSPSSCLGQTPTSPARYSPISKAVLGDDEITREPRKVVLHRGSTGL 476
           PD  N              C+  T                          V L+R    L
Sbjct: 258 PDEGN------------EDCVTYT--------------------------VQLYRHGGPL 193

Query: 477 GFNIVGGEDG-EGIFISFILAGGPADLSGELRKGDRIISVN 516
           G  I G ED  + I IS + AGG A  +G +  GDR++ +N
Sbjct: 192 GITISGTEDPLDNIVISELTAGGLAQKTGAMHVGDRLLGIN 70
>03831
          Length = 1143

 Score = 48.1 bits (113), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 35/101 (34%), Positives = 50/101 (49%), Gaps = 4/101 (3%)
 Frame = +3

Query: 431 VSPSSCLGQTPTSPARYSPISKAVLGD--DEITREPRKVVLHRGS--TGLGFNIVGGEDG 486
           V  S+  GQ   +  RY P     +GD  D  T  PR   + R S   G GFN+   +  
Sbjct: 24  VVSSATGGQGKLTCNRYRPWQLINMGDGGDSPTLVPRLCHIVRWSDFNGYGFNLHAEKGK 203

Query: 487 EGIFISFILAGGPADLSGELRKGDRIISVNSVDLRAASHEQ 527
            G FI  +  G PA+ +G L+ GDRI+ VN  ++   +H+Q
Sbjct: 204 AGQFIGKVDEGSPAEAAG-LKAGDRIVEVNGTNIGNENHQQ 323

 Score = 42.7 bits (99), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 44/187 (23%), Positives = 78/187 (41%), Gaps = 10/187 (5%)
 Frame = +3

Query: 349 YVTKIIEGGAAHKDGKLQIGDKLLAVNSVCLEEVTHEEAVTALKNTSDFVYLKVA----- 403
           ++ K+ EG  A   G L+ GD+++ VN   +    H++ V  +K   D   L V      
Sbjct: 213 FIGKVDEGSPAEAAG-LKAGDRIVEVNGTNIGNENHQQVVGRIKAGGDETRLLVVDQETD 389

Query: 404 ---KPTSMYINDGYAPPDITNSSSQSVDNHVSPSSCLGQTPTSPARYSPISKAVLGDDEI 460
              K     +           ++ +  DN  +  + +     +     P  ++ L D+  
Sbjct: 390 QHYKEEKRVVRGDLPETRFMTAAREQKDNXENQEAEIAAVVEATNGTEPEPQS-LPDESS 566

Query: 461 TREPRKVVLHRGST--GLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDRIISVNSV 518
              PR   L + +   G GFN+   +D  G +I  +    PA+  G L++GDRII VN  
Sbjct: 567 LYAPRLCHLCKWADFDGYGFNLHAEKDKPGQYIGSVDPNSPAETGG-LKEGDRIIEVNGE 743

Query: 519 DLRAASH 525
           ++   +H
Sbjct: 744 NIETTNH 764
>27345
          Length = 496

 Score = 47.4 bits (111), Expect = 3e-05,   Method: Composition-based stats.
 Identities = 22/62 (35%), Positives = 37/62 (59%)
 Frame = +3

Query: 343 PGDNSIYVTKIIEGGAAHKDGKLQIGDKLLAVNSVCLEEVTHEEAVTALKNTSDFVYLKV 402
           PG   I++  + +GGAA KDG++Q+ D+++ V+   L  VT   A + L+NTS  V   +
Sbjct: 12  PGKLGIFIKTLTDGGAAQKDGRIQVNDQIIEVDGKSLVGVTQAYAASVLRNTSGQVTFHI 191

Query: 403 AK 404
            +
Sbjct: 192 GR 197

 Score = 43.5 bits (101), Expect = 4e-04,   Method: Composition-based stats.
 Identities = 24/69 (34%), Positives = 38/69 (55%), Gaps = 1/69 (1%)
 Frame = +3

Query: 253 IFITKIITGGAAAQDGRLRVNDCILRVNEADVRDVTHSKAVEALKEAGSIVRLYVKRRK- 311
           IFI  +  GGAA +DGR++VND I+ V+   +  VT + A   L+     V  ++ R K 
Sbjct: 27  IFIKTLTDGGAAQKDGRIQVNDQIIEVDGKSLVGVTQAYAASVLRNTSGQVTFHIGRDKD 206

Query: 312 PASEKIMEI 320
           PA  ++  +
Sbjct: 207 PAKSEVARL 233
>39267
          Length = 456

 Score = 42.7 bits (99), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 22/73 (30%), Positives = 43/73 (58%)
 Frame = +1

Query: 328 GLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGKLQIGDKLLAVNSVCLEEVTHEEA 387
           GLGF+I+G +        + IYV+++   G A + GK+ +GD++ +V ++  + + +E+A
Sbjct: 115 GLGFNISGNM-------RDGIYVSQLHNRGPASESGKIHVGDRIQSV-TIAYDNIVYEDA 270

Query: 388 VTALKNTSDFVYL 400
           +T L   S +  L
Sbjct: 271 LTILSYASPYPVL 309

 Score = 39.3 bits (90), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 21/41 (51%), Positives = 27/41 (65%)
 Frame = +1

Query: 475 GLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDRIISV 515
           GLGFNI G    +GI++S +   GPA  SG++  GDRI SV
Sbjct: 115 GLGFNISGNMR-DGIYVSQLHNRGPASESGKIHVGDRIQSV 234
>38751
          Length = 329

 Score = 37.7 bits (86), Expect = 0.023,   Method: Composition-based stats.
 Identities = 18/49 (36%), Positives = 27/49 (55%)
 Frame = +3

Query: 350 VTKIIEGGAAHKDGKLQIGDKLLAVNSVCLEEVTHEEAVTALKNTSDFV 398
           V  +IE G   +   L IGD++L VN      +TH EAVT ++N  + +
Sbjct: 42  VVYVIEEGCQAEQQGLNIGDRILDVNGTDFTHLTHAEAVTIMRNAWNVI 188
>01502
          Length = 1949

 Score = 35.0 bits (79), Expect = 0.15,   Method: Composition-based stats.
 Identities = 22/67 (32%), Positives = 38/67 (56%)
 Frame = +1

Query: 250 DSSIFITKIITGGAAAQDGRLRVNDCILRVNEADVRDVTHSKAVEALKEAGSIVRLYVKR 309
           D  I++T I     AA+ G L+++D IL++N  D   VTH +AVE +++   +  L  ++
Sbjct: 28  DKGIYVTFIYENSPAARCG-LQLHDKILQLNGKDFTVVTHKQAVENIRKKPVLKMLVYRK 204

Query: 310 RKPASEK 316
             P  +K
Sbjct: 205 GVPQLQK 225

 Score = 33.1 bits (74), Expect = 0.57,   Method: Composition-based stats.
 Identities = 20/48 (41%), Positives = 28/48 (58%)
 Frame = +1

Query: 345 DNSIYVTKIIEGGAAHKDGKLQIGDKLLAVNSVCLEEVTHEEAVTALK 392
           D  IYVT I E   A + G LQ+ DK+L +N      VTH++AV  ++
Sbjct: 28  DKGIYVTFIYENSPAARCG-LQLHDKILQLNGKDFTVVTHKQAVENIR 168
>02951
          Length = 1076

 Score = 34.7 bits (78), Expect = 0.17,   Method: Composition-based stats.
 Identities = 22/67 (32%), Positives = 38/67 (56%)
 Frame = +2

Query: 250 DSSIFITKIITGGAAAQDGRLRVNDCILRVNEADVRDVTHSKAVEALKEAGSIVRLYVKR 309
           D  I++T I     AA+ G L+++D IL++N  D   VTH +AVE +++   +  L  ++
Sbjct: 14  DKGIYVTFIYENSPAARCG-LQLHDKILQLNGKDFTVVTHKQAVENIRKKPVLKMLVYRK 190

Query: 310 RKPASEK 316
             P  +K
Sbjct: 191 GVPQLQK 211

 Score = 32.7 bits (73), Expect = 0.63,   Method: Composition-based stats.
 Identities = 20/48 (41%), Positives = 28/48 (58%)
 Frame = +2

Query: 345 DNSIYVTKIIEGGAAHKDGKLQIGDKLLAVNSVCLEEVTHEEAVTALK 392
           D  IYVT I E   A + G LQ+ DK+L +N      VTH++AV  ++
Sbjct: 14  DKGIYVTFIYENSPAARCG-LQLHDKILQLNGKDFTVVTHKQAVENIR 154
>37412
          Length = 757

 Score = 34.3 bits (77), Expect = 0.26,   Method: Composition-based stats.
 Identities = 15/39 (38%), Positives = 24/39 (61%)
 Frame = -3

Query: 826 GKHCILDVSGNAIKRLQIAQLYPISIFIKPKSMENIMEM 864
           GK C+LDV+  ++K L+ A+  P  +FI   S+E +  M
Sbjct: 629 GKMCVLDVNPTSLKVLKTAEFLPYIVFIAAPSVEALKVM 513
>37239
          Length = 453

 Score = 33.9 bits (76), Expect = 0.27,   Method: Composition-based stats.
 Identities = 15/28 (53%), Positives = 20/28 (71%)
 Frame = -3

Query: 344 GDNSIYVTKIIEGGAAHKDGKLQIGDKL 371
           G + IY+  I  GGAA KDG+L +GD+L
Sbjct: 85  GRHGIYIRHITIGGAAAKDGQLAVGDEL 2
>30740
          Length = 488

 Score = 32.7 bits (73), Expect = 0.67,   Method: Compositional matrix adjust.
 Identities = 14/30 (46%), Positives = 19/30 (63%)
 Frame = +2

Query: 598 SGLPSQGLNFRFGDILHVINASDDEWWQAR 627
           SG   + L F  GDIL +I+  ++EWW AR
Sbjct: 212 SGRDPEDLPFSKGDILELISKDEEEWWTAR 301
>12324
          Length = 946

 Score = 32.0 bits (71), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 14/41 (34%), Positives = 22/41 (53%)
 Frame = +3

Query: 586 VRALFDYDKTKDSGLPSQGLNFRFGDILHVINASDDEWWQA 626
           V A++DY+  KD       L F    +++VI  +DD WW+ 
Sbjct: 696 VVAIYDYEAEKD-----DELTFSENSVIYVIRKNDDGWWEG 803
>30747
          Length = 1168

 Score = 32.0 bits (71), Expect = 1.2,   Method: Composition-based stats.
 Identities = 25/77 (32%), Positives = 38/77 (49%)
 Frame = +3

Query: 766 VPHTTRPKRDYEVDGRDYHFVTSREQMEKDIQEHKFIEAGQYNNHLYGTSVQSVRAVAEK 825
           +P   RP    +   RD   V+  E +E   QE  F +   Y   L+GT + +V  + + 
Sbjct: 102 LPGLPRP----DAKPRDVKIVSPAEILEL-CQEEDFYKV--YEVDLHGTEITAVPDLEKF 260

Query: 826 GKHCILDVSGNAIKRLQ 842
            K  +LDVSGN I ++Q
Sbjct: 261 RKLRVLDVSGNYITKIQ 311
>33158
          Length = 1075

 Score = 29.3 bits (64), Expect = 6.9,   Method: Compositional matrix adjust.
 Identities = 11/26 (42%), Positives = 19/26 (73%)
 Frame = +2

Query: 346  NSIYVTKIIEGGAAHKDGKLQIGDKL 371
            +S+ + +I++GGAA K G L  GD++
Sbjct: 998  DSVLIARIVKGGAAEKSGLLHEGDEI 1075
>14655
          Length = 507

 Score = 28.9 bits (63), Expect = 9.0,   Method: Composition-based stats.
 Identities = 14/44 (31%), Positives = 22/44 (50%)
 Frame = +3

Query: 73  CEPVQPVTTWEIASLPSTAVTSETLPGSLSPPVEKYRYQDEEVL 116
           C P     TW I + P+T   + T P +LSP + +    D ++L
Sbjct: 360 CHP-PTFPTWSIPTWPATQTATVTSPNTLSPALNEKGSGDNDIL 488
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6671549|ref|NP_031479.1| peroxiredoxin 6 [Mus
musculus]
         (224 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

09123                                                                 240   6e-67
09130                                                                  75   2e-14
10721                                                                  74   4e-14
18197                                                                  28   2.5  
14109                                                                  27   9.3  
>09123
          Length = 1944

 Score =  240 bits (612), Expect(2) = 6e-67,   Method: Compositional matrix adjust.
 Identities = 119/194 (61%), Positives = 141/194 (72%)
 Frame = -3

Query: 31   DSWGILFSHPRDFTPVCTTELGRAAKLAPEFAKRNVKLIALSIDSVEDHLAWSKDINAYN 90
            +SW ILFSHP D+TPVCTTELGR   L  EF KR  K+ ALS D  E H  W+KD+  Y 
Sbjct: 1612 NSWAILFSHPADYTPVCTTELGRVLNLIGEFEKRKCKVFALSCDGPESHKGWAKDVQKYA 1433

Query: 91   GETPTEKLPFPIIDDKGRDLAILLGMLDPVEKDANNMPVTARVVFIFGPDKKLKLSILYP 150
            G     K P+PII D+ RDLA+ LGM+DP EK  + +P+T R VFI GPDKKLKLS+LYP
Sbjct: 1432 GVDTDTKFPYPIIADEKRDLAVQLGMVDPAEKTKDGLPLTCRAVFIIGPDKKLKLSLLYP 1253

Query: 151  ATTGRNFDEILRVVDSLQLTGTKPVATPVDWKKGESVMVVPTLSEEEAKQCFPKGVFTKE 210
            ATTGRNFDEILRV+DSLQLT TK VATP +W+ G   MV+P++S+EEAK+ F K V T  
Sbjct: 1252 ATTGRNFDEILRVLDSLQLTATKKVATPENWQPGGKCMVIPSVSDEEAKKLFTK-VETIS 1076

Query: 211  LPSGKKYLRYTPQP 224
            +PS K YLR T QP
Sbjct: 1075 VPSXKPYLRMTDQP 1034

 Score = 31.6 bits (70), Expect(2) = 6e-67,   Method: Compositional matrix adjust.
 Identities = 12/21 (57%), Positives = 15/21 (71%)
 Frame = -1

Query: 7    LGDEAPNFEANTTIGRIRFHD 27
            LGD  PNF A T +G I+FH+
Sbjct: 1683 LGDTFPNFTAQTNLGEIKFHE 1621
>09130
          Length = 1000

 Score = 75.1 bits (183), Expect = 2e-14,   Method: Compositional matrix adjust.
 Identities = 50/167 (29%), Positives = 77/167 (46%)
 Frame = +1

Query: 23  IRFHDFLGDSWGILFSHPRDFTPVCTTELGRAAKLAPEFAKRNVKLIALSIDSVEDHLAW 82
           I+  DF G  + + F +P DFT VC TE+   +    +F   N +++A S+DS   HLAW
Sbjct: 259 IKLSDFRG-KYLVFFFYPLDFTFVCPTEIVAFSDNVGKFKSINTEVVACSVDSQFTHLAW 435

Query: 83  SKDINAYNGETPTEKLPFPIIDDKGRDLAILLGMLDPVEKDANNMPVTARVVFIFGPDKK 142
              IN    +     L  P++ D   D+A   G+         ++  + R +FI  P   
Sbjct: 436 ---INTPRNQGGLGPLKIPLLSDITHDIAKAYGVY------LQDLGHSLRGLFIIDPKGI 588

Query: 143 LKLSILYPATTGRNFDEILRVVDSLQLTGTKPVATPVDWKKGESVMV 189
           L+   +     GR+ DE LR+V + Q T       PV WK G   ++
Sbjct: 589 LRQITMNDLPVGRSVDETLRLVQAFQYTDAHGEVCPVGWKPGSDTII 729
>10721
          Length = 1542

 Score = 74.3 bits (181), Expect = 4e-14,   Method: Compositional matrix adjust.
 Identities = 52/190 (27%), Positives = 82/190 (43%), Gaps = 4/190 (2%)
 Frame = -2

Query: 3    GGLLLGDEAPNFEANTTIG----RIRFHDFLGDSWGILFSHPRDFTPVCTTELGRAAKLA 58
            G L +   AP F     +      ++  D+ G  + +LF +P DFT VC TE+   +   
Sbjct: 1463 GQLAIQKPAPEFSVQAVVDGDFKTVKLSDYKG-KYVVLFFYPLDFTFVCPTEIIAFSDRV 1287

Query: 59   PEFAKRNVKLIALSIDSVEDHLAWSKDINAYNGETPTEKLPFPIIDDKGRDLAILLGMLD 118
             EF     +++A S DSV  HLAW   +N    +     +  P++ DK  +L+ + G L 
Sbjct: 1286 EEFRSIQCEVLAASTDSVFSHLAW---VNTPRKQGGLGNMKIPLLADKTLELSRMYGCLK 1116

Query: 119  PVEKDANNMPVTARVVFIFGPDKKLKLSILYPATTGRNFDEILRVVDSLQLTGTKPVATP 178
              E       +  R ++I      L+   +     GR+ DE LR+V + Q T       P
Sbjct: 1115 EDEG------IAYRALYIIDDKGTLRQITMNDLPVGRSVDETLRLVQAFQFTDKHGEVCP 954

Query: 179  VDWKKGESVM 188
              WK G   +
Sbjct: 953  AGWKPGADTI 924
>18197
          Length = 463

 Score = 28.5 bits (62), Expect = 2.5,   Method: Compositional matrix adjust.
 Identities = 34/120 (28%), Positives = 52/120 (43%), Gaps = 14/120 (11%)
 Frame = +3

Query: 73  IDSVEDHLAWSKDINAYNGETPTEKLPFPIIDDKGRDLAILL---GMLDPVEK-DANNMP 128
           + S  DHL      N  + +      P PI +D  R   + L   G++ P  +   +  P
Sbjct: 51  MGSTVDHLTVLPKANRVDPQL----APPPITEDDARKGILSLIERGLIPPAAQLTLDPSP 218

Query: 129 VTARVVFIFGPDKKLK---------LSILYPATTGRNFDE-ILRVVDSLQLTGTKPVATP 178
           V  RV+ +  PD+K K         LS L+  T GR+  E     ++S+     +PVATP
Sbjct: 219 VRHRVITLHDPDEKTKTPISEMATTLSSLHYDTNGRSAGEGGENNLESMPTVPPRPVATP 398
>14109
          Length = 1233

 Score = 26.6 bits (57), Expect = 9.3,   Method: Compositional matrix adjust.
 Identities = 10/22 (45%), Positives = 15/22 (68%)
 Frame = +1

Query: 86  INAYNGETPTEKLPFPIIDDKG 107
           +N  N E  ++KLP P+ DD+G
Sbjct: 532 LNCINEEVTSKKLPAPVDDDQG 597
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|82887368|ref|XP_130646.6| PREDICTED: ADP-ribosylation
factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
[Mus musculus]
         (1792 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

25800                                                                 252   7e-67
11688                                                                 236   6e-62
30249                                                                  76   1e-13
20966                                                                  44   7e-04
13952                                                                  42   0.003
17762                                                                  37   0.089
32331                                                                  32   2.9  
>25800
          Length = 431

 Score =  252 bits (644), Expect = 7e-67,   Method: Compositional matrix adjust.
 Identities = 115/140 (82%), Positives = 129/140 (92%)
 Frame = +2

Query: 1147 DHFNKVGCNPNEDVAIFAVDSLRQLSMKFLEKGELANFRFQKDFLRPFEHIMKKNRSPTI 1206
            DHFNKVGC+P EDVA FAVDSLRQLSMKF+EKGE ANFRFQKDFLRPFEHIMK+NRSPTI
Sbjct: 2    DHFNKVGCSPMEDVAFFAVDSLRQLSMKFIEKGEFANFRFQKDFLRPFEHIMKRNRSPTI 181

Query: 1207 RDMVIRCIAQMVSSQAANIRSGWKNIFAVFHQAASDHDGNIVELAFQTTGHIVSTIFQHH 1266
            RDMV+RC+AQMV+SQAA+I+SGWKNIF+VFH AASDHD  IVELAFQTTG I+ ++F+ H
Sbjct: 182  RDMVVRCVAQMVNSQAASIKSGWKNIFSVFHLAASDHDEGIVELAFQTTGKIILSVFEKH 361

Query: 1267 FPAAIDSFQDAVKCLSEFAC 1286
            F + IDSFQDAVKCLSEFAC
Sbjct: 362  FASIIDSFQDAVKCLSEFAC 421
>11688
          Length = 590

 Score =  236 bits (602), Expect = 6e-62,   Method: Compositional matrix adjust.
 Identities = 110/174 (63%), Positives = 138/174 (79%), Gaps = 5/174 (2%)
 Frame = +1

Query: 1550 QKLLASLLIKCVVQLELIQTIDNIVFYPATSKKEDAEHMVAAQQDTLDAEIH-----IET 1604
            Q+L   LLI+CVVQLELIQTIDNIVF+PATS+KEDAE++  AQ    + ++H     I+ 
Sbjct: 40   QQLFQGLLIRCVVQLELIQTIDNIVFFPATSRKEDAENLAVAQGSVDECQLHEPGHEIQH 219

Query: 1605 ENQGMYKFMSSQHLFKLLDCLQESHSFSKAFNSNYEQRTVLWRAGFKGKSKPNLLKQETS 1664
            E+QGMY+F+SSQ L    DCL +SH F+K FNSN+EQR VLW+AGFKGK+KPNLLKQET 
Sbjct: 220  EDQGMYQFLSSQQLLMFTDCLLQSHRFAKQFNSNHEQRNVLWKAGFKGKAKPNLLKQETQ 399

Query: 1665 SLACCLRILFRMYVDENRRDSWDEIQQRLLRVCSEALAYFITVNSESHREAWTS 1718
            SLAC  RILFRMY DE R D+W +++++LL VCSEAL YF+++ S+SHREAW S
Sbjct: 400  SLACMFRILFRMYNDETRTDAWPQVEEKLLHVCSEALEYFLSLQSDSHREAWCS 561
>30249
          Length = 822

 Score = 76.3 bits (186), Expect = 1e-13,   Method: Compositional matrix adjust.
 Identities = 40/82 (48%), Positives = 55/82 (67%), Gaps = 3/82 (3%)
 Frame = -2

Query: 745 EAQKIDRLMEKFAARYIECNQGQTL-FASADTAYVLAYSIIMLTTDLHSPQVK--NKMTK 801
           EAQKI+RLME FA RY +CN  Q   F + DT ++LA++IIML TDLH+  VK   KM  
Sbjct: 821 EAQKIERLMEAFAERYCQCNPDQVKNFKTFDTVFLLAFAIIMLNTDLHNSSVKPERKMKL 642

Query: 802 EQYIKMNRGINDSKDLPEEYLS 823
           E +++  RGI+D +D+  +  S
Sbjct: 641 EDFVRNLRGIDDGEDVDGDLAS 576
>20966
          Length = 686

 Score = 43.5 bits (101), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 19/55 (34%), Positives = 34/55 (61%)
 Frame = -1

Query: 499 SFEHRWMVIQTLTRICADAQCVVDIYVNYDCDLNAANIFERLVNDLSKIAQGRSG 553
           +++ R + ++++ ++      V ++Y+NYDCDL  +N+FE L   LSK A   SG
Sbjct: 683 TYDQREIALESIVQLWRIPGLVTELYLNYDCDLYCSNLFEELTKLLSKNAFPVSG 519

 Score = 39.3 bits (90), Expect = 0.013,   Method: Composition-based stats.
 Identities = 18/45 (40%), Positives = 27/45 (60%), Gaps = 2/45 (4%)
 Frame = -3

Query: 647 IKQQKEIIEHGIELFNKKPKRGIQFLQEQGMLGAAVE--DIAQFL 689
           ++ ++     G E FN+KP +GI FLQEQG+L    +   +A FL
Sbjct: 156 VQTKERAYNQGTEYFNQKPAKGIAFLQEQGLLATPXDPGQVATFL 22
>13952
          Length = 577

 Score = 41.6 bits (96), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 19/39 (48%), Positives = 27/39 (69%)
 Frame = -3

Query: 800 TKEQYIKMNRGINDSKDLPEEYLSSIYDEIEGKKIAMKE 838
           T E++I+MNR IND   LPEE L+S+YD I+ +   + E
Sbjct: 575 TVERFIQMNRDINDGDSLPEELLTSLYDSIKKEPFKIPE 459
>17762
          Length = 1950

 Score = 36.6 bits (83), Expect = 0.089,   Method: Composition-based stats.
 Identities = 16/49 (32%), Positives = 25/49 (51%), Gaps = 5/49 (10%)
 Frame = -1

Query: 1099 RWLCAVSMDE-----LASPHHPRMFSLQKIVEISYYNMNRIRLQWSRIW 1142
            RW C     E      ++ H PR         I+ YN++R++L+WSR+W
Sbjct: 861  RWTC*EPAGEGRWELQSNQHRPRGLGKSVPTSINQYNLDRLKLKWSRVW 715
>32331
          Length = 316

 Score = 31.6 bits (70), Expect = 2.9,   Method: Composition-based stats.
 Identities = 21/66 (31%), Positives = 32/66 (48%)
 Frame = +1

Query: 840 KEHTIATKSTKQSVASEKQRRLLYNVEMEQMAKTAKALMEAVSHAKAPFTSATHLDHVRP 899
           ++  IA    K SV   +  R++  VE+  +  T K    AV H ++PF S T L +   
Sbjct: 22  RQQFIAPNIKKNSVRERQYNRMVQVVELLPLW*TLKL---AVGH*RSPFGSMTQLKY*HG 192

Query: 900 MFKLVW 905
            FK+ W
Sbjct: 193 TFKM*W 210
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|134288917|ref|NP_084514.2| cytoplasmic dynein 1 heavy
chain 1 [Mus musculus]
         (4644 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

28569                                                                 253   1e-66
35960                                                                 243   1e-63
23257                                                                 201   1e-59
20410                                                                 132   4e-40
28658                                                                 149   4e-35
14519                                                                 147   1e-34
37041                                                                 107   1e-22
24890                                                                  99   3e-20
19780                                                                  89   4e-17
12392                                                                  87   1e-16
36750                                                                  60   2e-15
27572                                                                  83   3e-15
20622                                                                  79   5e-14
07275                                                                  75   5e-13
32781                                                                  71   1e-11
35288                                                                  58   1e-07
06548                                                                  55   5e-07
20268                                                                  44   0.002
13559                                                                  42   0.008
25583                                                                  40   0.020
31256                                                                  35   0.94 
30327                                                                  34   1.5  
00810                                                                  33   2.7  
15303                                                                  33   3.0  
05344                                                                  32   4.0  
>28569
          Length = 475

 Score =  253 bits (646), Expect = 1e-66,   Method: Compositional matrix adjust.
 Identities = 121/156 (77%), Positives = 135/156 (86%)
 Frame = -3

Query: 3434 MIRDLEASIARYKEEYAVLISEAQAIKADLAAVEAKVNRSTALLKSLSAERERWEKTSET 3493
            +I+ LE SI +YKEEYAVLIS+AQAIKADLAAVEAKV RS ALL SL  E++RWE  SET
Sbjct: 470  LIQGLEQSIGKYKEEYAVLISQAQAIKADLAAVEAKVERSVALLNSLGNEKQRWEAGSET 291

Query: 3494 FKNQMSTIAGDCLLSAAFIAYAGYFDQQMRQNLFTTWSHHLQQANIQFRTDIARTEYLSN 3553
            FK QM+TI GD LLSAAF+AYAGYFDQQMRQNLF  W +HLQ A IQFR D+ARTEYLSN
Sbjct: 290  FKQQMATIIGDVLLSAAFMAYAGYFDQQMRQNLFGNWCNHLQLAMIQFRPDLARTEYLSN 111

Query: 3554 ADERLRWQASSLPADDLCTENAIMLKRFNRYPLIID 3589
            ADERL WQA++LP D+LCTENAIMLKRFNRYPLI+D
Sbjct: 110  ADERLNWQANALPTDELCTENAIMLKRFNRYPLIVD 3
>35960
          Length = 734

 Score =  243 bits (621), Expect = 1e-63,   Method: Compositional matrix adjust.
 Identities = 129/248 (52%), Positives = 169/248 (68%), Gaps = 4/248 (1%)
 Frame = +1

Query: 3866 FNRVARGMLHQDHITFAMLLARIKLKGTVGEPTYDAEFQHFLRGKEIVLSAGSTPKIQGL 3925
            + RV  GML++D ITFA+ L RI L+G   E TYD EF HFLR +E +L   STP +   
Sbjct: 1    YGRVGCGMLYEDRITFAIQLCRIHLEGMASEGTYDVEFNHFLRSQEGLLMDKSTPLLLAS 180

Query: 3926 TVEQAE-AVVRLSCLPAFKD-LIAKVQADEQFGIWLDSSSPEQ--TVPYLWSEETPTTPI 3981
               + +   V +SC P+      +++    + G W   + P Q    P LWSE+   T I
Sbjct: 181  PSNRIQPCCVSVSCQPSETC*TKSRITLSSRLG-W---TVPSQRWDFPPLWSEDKAQTAI 348

Query: 3982 GQAIHRLLLIQAFRPDRLLAMAHMFVSTNLGESFMSIMEQPLDLTHIVGTEVKPNTPVLM 4041
            G+++H LL+IQA RPDRL+AMA +FV   LG  F+ I E+ L+L+ IV TE+K +TPVLM
Sbjct: 349  GKSVHGLLVIQALRPDRLIAMARIFVEKTLGSDFVHITEKELNLSLIVETEIKGSTPVLM 528

Query: 4042 CSVPGYDASGHVEDLAAEQNTQITSIAIGSAEGFNQADKAINTAVKSGRWVMLKNVHLAP 4101
            CS PGYD S  V+DLAAE + Q+TSIAIGSAEGF+QA+KAIN++ KSGRWV+LKNVHLAP
Sbjct: 529  CSAPGYDPSSRVDDLAAELSKQMTSIAIGSAEGFSQAEKAINSSSKSGRWVLLKNVHLAP 708

Query: 4102 GWLMQLEK 4109
             WL+QLE+
Sbjct: 709  QWLVQLER 732
>23257
          Length = 1984

 Score =  201 bits (511), Expect(2) = 1e-59,   Method: Compositional matrix adjust.
 Identities = 101/170 (59%), Positives = 128/170 (75%), Gaps = 2/170 (1%)
 Frame = -2

Query: 4477 VSDFSERIKQLQNISQAAASGGAKELKNIHVCLGGLFVPEAYITATRQYVAQANSWSLEE 4536
            ++DFS R+KQLQ I QA+ +  ++ELKN+++ LGG+F+PEAYITATRQ+VAQAN+WSLEE
Sbjct: 1863 ITDFSLRVKQLQAIVQASQASSSRELKNLNMWLGGMFIPEAYITATRQFVAQANNWSLEE 1684

Query: 4537 LCLEVNVTASQSATLDACSFGVTGLKLQGATCSNNKLSLSNAISTVLPLTQLRWVKQTSA 4596
            L L+V V   +   LD CSFGV GLKLQGA CSNNKL LS  IST L LT LRW+K   +
Sbjct: 1683 LYLDVLVQDGKPQALDDCSFGVLGLKLQGAACSNNKLQLSTTISTDLKLTVLRWIKVDGS 1504

Query: 4597 EKKASVVTLPVYLNFTRADLIFTVDFEIATKEDPR--SFYERGVAVLCTE 4644
            +   + VTLPVYLN TR  L+FTVDF+ A K   +   FYERGVA++C++
Sbjct: 1503 KNMDNRVTLPVYLNATRDQLLFTVDFDCAEKTAGKDHGFYERGVALICSD 1354

 Score = 50.8 bits (120), Expect(2) = 1e-59,   Method: Composition-based stats.
 Identities = 20/38 (52%), Positives = 31/38 (81%)
 Frame = -3

Query: 4438 GKKKQTNYLRTLINELVKGILPRSWSHYTVPAGMTVIQ 4475
            G+ +  ++ R+++ +LVKGI+P+SW  YTVPAG+TVIQ
Sbjct: 1979 GENEAHHHHRSMMADLVKGIIPKSWRRYTVPAGLTVIQ 1866
>20410
          Length = 754

 Score =  132 bits (332), Expect(2) = 4e-40,   Method: Composition-based stats.
 Identities = 63/141 (44%), Positives = 86/141 (60%)
 Frame = -2

Query: 1877 LVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKALGHQLGRFVLVFNCDETFDF 1936
            LV TPLTDRCY T+  AL   LGG+P GPAGTGKTE+ K L   + +  +VFNC +  D+
Sbjct: 393  LVITPLTDRCYRTLFGALHLHLGGAPEGPAGTGKTETTKDLAKAVAKQCVVFNCSDGLDY 214

Query: 1937 QAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQVQCIQEALREHSNPNYDKTSAPIT 1996
             A+G+ F GL   GAW CFDEFNR++  +LS V+QQ+  IQ  +   S+          T
Sbjct: 213  IALGKFFKGLASCGAWSCFDEFNRIDLEVLSVVAQQILTIQRGINSGSD----------T 64

Query: 1997 CELLNKQVKVSPDMAIFITMN 2017
                  ++++ P  ++FITMN
Sbjct: 63   LLFEGTEIRLDPTCSVFITMN 1

 Score = 54.3 bits (129), Expect(2) = 4e-40,   Method: Compositional matrix adjust.
 Identities = 28/79 (35%), Positives = 41/79 (51%)
 Frame = -1

Query: 1803 RRKLEHLITELVHQRDVTRSLIKSKIDNAKSFEWLSQMRFYFDPKQTDVLQQLSIQMANA 1862
            R  L+ +I   VH RDV   L K +I +   F WLSQ+R+Y++        Q+  +M N+
Sbjct: 598  RVTLQAMIVLEVHSRDVLAELCKVQISSELDFNWLSQLRYYWEEG------QMITRMINS 437

Query: 1863 KFNYGFEYLGVQDKLVQTP 1881
               YG+EYLG   +    P
Sbjct: 436  MLKYGYEYLGNSGRTXHHP 380
>28658
          Length = 552

 Score =  149 bits (375), Expect = 4e-35,   Method: Compositional matrix adjust.
 Identities = 75/149 (50%), Positives = 99/149 (66%)
 Frame = +3

Query: 1953 GCFDEFNRLEERMLSAVSQQVQCIQEALREHSNPNYDKTSAPITCELLNKQVKVSPDMAI 2012
             CFDEFNR++  +LS V+QQ+  I +A ++  + +               ++ + P  A+
Sbjct: 3    ACFDEFNRIDIEVLSVVAQQITTIHKAQQQRLDRSI----------FEGVELVLRPSCAV 152

Query: 2013 FITMNPGYAGRSNLPDNLKKLFRSLAMTKPDRQLIAQVMLYSQGFRTAEVLANKIVPFFK 2072
            FITMNPGYAGR+ LPDNLK LFR +AM  PD  LIA++ L+S GF  A  LA KIV  FK
Sbjct: 153  FITMNPGYAGRTELPDNLKALFRPVAMMVPDYALIAEISLFSFGFSDARNLAKKIVTTFK 332

Query: 2073 LCDEQLSSQSHYDFGLRALKSVLVSAGNV 2101
            L  EQLSSQ HYDFG+RA+KSV+ +AGN+
Sbjct: 333  LSSEQLSSQDHYDFGMRAVKSVISAAGNL 419
>14519
          Length = 945

 Score =  147 bits (370), Expect = 1e-34,   Method: Compositional matrix adjust.
 Identities = 72/208 (34%), Positives = 117/208 (56%), Gaps = 1/208 (0%)
 Frame = -3

Query: 2907 LVLFNEVLDHVLRIDRIFRQPQGHLLLIGVSGAGKTTLSRFVAWMNGLSVYQIKVHRKYT 2966
            LV F + + H+L+I RI R P+GH LL+GV G+GK +L+R  +++ G   +QI + R Y 
Sbjct: 682  LVFFKDAMIHLLKISRIIRTPRGHALLVGVGGSGKQSLTRLSSFIAGYKTFQITLTRSYN 503

Query: 2967 GEDFDEDLRTVLRRSGCKNEKIAFIMDESNVLDSGFLERMNTLLANGEVPGLFEGDEYAT 3026
              +  +DL+ + R +G + + I FI  +  + D GFLE +N +L++G V  LF  DE   
Sbjct: 502  VSNLLDDLKNLYRTAGQEGKGITFIFTDQEIKDEGFLEYLNNMLSSGVVANLFARDEMDE 323

Query: 3027 LMTQCKEGAQKE-GLMLDSHEELYKWFTSQVIRNLHVVFTMNPSSEGLKDRAATSPALFN 3085
            ++ +     + E      S+E LY+++ S+V  NLHV    +P  E  + RA   P L +
Sbjct: 322  ILGELVPVMKXEFPRRPPSNENLYEYYLSRVRNNLHVTLCFSPVGEKFRQRALKFPGLIS 143

Query: 3086 RCVLNWFGDWSTEALYQVGKEFTSKMDL 3113
             C ++WF  W  +AL  V   F ++ D+
Sbjct: 142  GCTMDWFQRWPKDALIAVADHFLAEFDI 59
>37041
          Length = 350

 Score =  107 bits (267), Expect = 1e-22,   Method: Composition-based stats.
 Identities = 52/105 (49%), Positives = 70/105 (66%)
 Frame = -2

Query: 2273 WTDGLFTHVLRKIIDNVRGELQKRQWIVFDGDVDPEWVENLNSVLDDNKLLTLPNGERLS 2332
            WTDG+F+ + R+     +GE     W+V DG VD  W+ENLNSVLDDNK LTL NG+R+ 
Sbjct: 310  WTDGIFSTLWRRTHKTKKGE---HVWLVLDGPVDAIWIENLNSVLDDNKTLTLANGDRIP 140

Query: 2333 LPPNVRIMFEVQDLKYATLATVSRCGMVWFSEDVLSTDMIFNNFL 2377
            + PN +I+FEV ++  A+ ATVSR GMV+ S  +L  D I   +L
Sbjct: 139  MAPNCKIIFEVHNIDNASPATVSRNGMVFMSSSILDWDPILQGWL 5
>24890
          Length = 425

 Score = 99.4 bits (246), Expect = 3e-20,   Method: Compositional matrix adjust.
 Identities = 48/79 (60%), Positives = 61/79 (77%), Gaps = 2/79 (2%)
 Frame = -2

Query: 4275 SFDSEFKLACKVD--GHKDIQMPDGIRREEFVQWVELLPDAQTPSWLGLPNNAERVLLTT 4332
            S+DS F L   VD    K I MPDG+RRE+FVQ+V+ L   QTPSWLGLPNNAE+VLLTT
Sbjct: 280  SYDSSFVLVRNVDDISGKHIGMPDGVRREQFVQFVDNLEGPQTPSWLGLPNNAEKVLLTT 101

Query: 4333 QGVDMISKMLKMQMLEDED 4351
             G DMI+++++MQ+LE+ D
Sbjct: 100  LGSDMIARLMRMQLLEEAD 44
>19780
          Length = 1009

 Score = 89.0 bits (219), Expect = 4e-17,   Method: Compositional matrix adjust.
 Identities = 68/263 (25%), Positives = 117/263 (44%), Gaps = 29/263 (11%)
 Frame = +1

Query: 2480 QIEQLERYIQRYLVYAILWSLSGDSRLKMRAELGEYIRRITT---VPLPTAPNVPIIDYE 2536
            Q+ ++   I+ + +++ +WS++       R +  E++R         L       + DY 
Sbjct: 34   QMGRINELIEPWFIFSFVWSVAATCDNDGRVKFSEWLREKMAEKKCKLKFPEEGLVYDYM 213

Query: 2537 VSISG-------------------EWSPWQAKVPQIEVETHKVAAPDVVVPTLDTVRHEA 2577
            +  +G                   +W  W   +P  EV      + D++VPT+DT+R   
Sbjct: 214  LDDAGISSTDRDDIEEEEAVHKEVQWRNWMHGLPTYEVAPDTKFS-DILVPTIDTIRSAY 390

Query: 2578 LLYTWLAEHKPLVLCGPPGSGKTMTLFSAL------RALPDMEVVGLNFSSATTPELLLK 2631
            ++   L+ +K ++  GP G+GKTMT+   L        +PD  V     S+  T +L+  
Sbjct: 391  IIGMLLSNNKTVLSVGPTGTGKTMTISDKLTRNMAKEYIPDFIVFSAKTSANQTQDLI-- 564

Query: 2632 TFDHYCEYRRTPNGVVLAPVQLGKWLVLFCDEINLPDMDKYGTQRVISFIRQMVEHGGFY 2691
              D   + RR   GV   P  LGK+ + F D++N+P  + YG Q  I  IRQ ++  G+Y
Sbjct: 565  --DGKLDKRR--KGVFGPP--LGKYFIFFIDDLNMPAREVYGAQPPIELIRQWMDFNGWY 726

Query: 2692 -RTSDQTWVKLERIQFVGACNPP 2713
             R +   +  L  + F  A  PP
Sbjct: 727  DRKAIGDFRNLVDVNFACAMGPP 795
>12392
          Length = 445

 Score = 87.4 bits (215), Expect = 1e-16,   Method: Compositional matrix adjust.
 Identities = 52/144 (36%), Positives = 76/144 (52%)
 Frame = +3

Query: 1743 YQAQLVVLSAQIAWSENVENALSNVGGGGDVGPLQSVLSNVEVTLNVLADSVLMEQPPLR 1802
            + +Q+ +L  Q+ W+ + E AL+N     D   + +        LN+L D    +   + 
Sbjct: 30   FPSQIGLLGLQMIWTRDSEEALNN--ARVDKKIMTNTNQKFLDLLNMLIDQTTRDLTKIE 203

Query: 1803 RRKLEHLITELVHQRDVTRSLIKSKIDNAKSFEWLSQMRFYFDPKQTDVLQQLSIQMANA 1862
            R K E LIT  VHQ+D+   L++  I +   FEWL Q RFY+  + TD   Q  I + + 
Sbjct: 204  RTKFETLITIHVHQKDIFDDLVRMHIKSVNDFEWLKQSRFYY-KEDTD---QCVISITDV 371

Query: 1863 KFNYGFEYLGVQDKLVQTPLTDRC 1886
             F Y  E+LG  D+LV TPLTDRC
Sbjct: 372  DFLYMNEFLGCTDRLVITPLTDRC 443
>36750
          Length = 1066

 Score = 60.1 bits (144), Expect(2) = 2e-15,   Method: Compositional matrix adjust.
 Identities = 46/197 (23%), Positives = 86/197 (43%), Gaps = 17/197 (8%)
 Frame = -1

Query: 2657 LVLFCDEINLPDMDKYGTQRVISFIRQMVEHGGFYRTSDQT-WVKLERIQFVGACNPPTD 2715
            + +F D+IN+P ++++G Q     +RQ++E+GGFY       +  +  +QF+ A   P  
Sbjct: 787  MTVFLDDINMPIINEWGDQVANEIVRQLMENGGFYSLEKPGDFTTIADVQFLAAMIQPGG 608

Query: 2716 PGRKPLSHRFLRHVPVVYVDYPGPASLTQIYGTFNRAML---------------RLIPSL 2760
             GR  +  R  R   +     P   S+ +I+    +                  R++P  
Sbjct: 607  -GRNDIPQRLKRQFVIFNCTLPSNTSIDKIFSVIGQGHFCKERGFSNKVIEMVKRIVPVT 431

Query: 2761 RTYAEPLTAAMVEFYTMSQERFTQDTQPHYIYSPREMTRWVRGIFEALRPLETLPVEG-L 2819
            R   +     M+     +  +F      HYI++ R+++R  +G+ +      T+  E  L
Sbjct: 430  RRLWQLTKIKMLP----TPAKF------HYIFNLRDLSRIWQGMLKT--SSSTVNSEKVL 287

Query: 2820 IRIWAHEALRLFQDRLV 2836
            + +W HE  R+  DR V
Sbjct: 286  MYLWKHECCRVIADRCV 236

 Score = 43.1 bits (100), Expect(2) = 2e-15,   Method: Composition-based stats.
 Identities = 26/78 (33%), Positives = 45/78 (57%), Gaps = 2/78 (2%)
 Frame = -2

Query: 2565 VVVPTLDTVRHEALLYTWLAEHKPLVLCGPPGSGKTMTLFSALRAL-PDMEVV-GLNFSS 2622
            ++VP +D VR E L+ T   ++K ++L G  G+ KT+ +   +    P+  +   +NFSS
Sbjct: 1056 ILVPNVDNVRTEFLIDTISKQNKAVLLIGEQGTAKTVMINGYMGLYNPEFHLSETVNFSS 877

Query: 2623 ATTPELLLKTFDHYCEYR 2640
            ATTP +  +T + Y + R
Sbjct: 876  ATTPLMYQRTIESYVDKR 823
>27572
          Length = 403

 Score = 83.2 bits (204), Expect = 3e-15,   Method: Compositional matrix adjust.
 Identities = 44/123 (35%), Positives = 69/123 (56%), Gaps = 5/123 (4%)
 Frame = +2

Query: 1562 ETQRFQSISTEFLALMKKVSKSPLVMDVLNIQGVQRSLERLADLLGKIQKALGEYLERER 1621
            +++RF  I T+F  L+ +V K+   +D  N   +   LE L   L   +KAL EYLE +R
Sbjct: 2    DSKRFDGIDTDFKELVGQVEKTKNCVDATNQPKLYERLETLQHNLALCEKALAEYLETKR 181

Query: 1622 SSFPRFYFVGDEDLLEIIGNSKNVAKLQKHFKKMFAGVSSIILNEDNS-----VVLGISS 1676
             +FPRFYFV   DLL+I+ N  N   + +H  K+F  ++ +   +D+S     V  G+ S
Sbjct: 182  LAFPRFYFVSSSDLLDILSNGNNPVSVARHLTKLFDSMAQLKFEKDSSGNEIKVATGMHS 361

Query: 1677 REG 1679
            ++G
Sbjct: 362  KDG 370
>20622
          Length = 448

 Score = 78.6 bits (192), Expect = 5e-14,   Method: Composition-based stats.
 Identities = 49/161 (30%), Positives = 76/161 (47%), Gaps = 4/161 (2%)
 Frame = -2

Query: 4157 RTFSSIPVS--RICKSPNERARLYFLLAWFHAIIQERLRYAPLGWSKKYEFGESDLRSAC 4214
            RT++ I      I   P  +  LY +  + H I+QER ++ PLGW+  YEF  SD  ++ 
Sbjct: 441  RTYAGITQDYLDISNMPQWKPMLYGV-GFLHTIVQERRKFGPLGWNIPYEFNTSDYNASV 265

Query: 4215 DTVDTWLDDT--AKGRQNISPDKIPWSALKTLMAQSIYGGRVDNEFDQRLLNTFLERLFT 4272
              V   LDD    KG        + W  ++ +  +  YGGRV ++FD+RLLNTF    F 
Sbjct: 264  QFVQNHLDDMDIKKG--------VNWICVRYMFGEIQYGGRVTDDFDKRLLNTFCRVWFG 109

Query: 4273 TRSFDSEFKLACKVDGHKDIQMPDGIRREEFVQWVELLPDA 4313
               F   F        +K   +P   +  E+ +++  LP +
Sbjct: 108  ENMFTPAFNF------YKGYVIPKCAKINEYHEYINSLPSS 4
>07275
          Length = 1513

 Score = 75.5 bits (184), Expect = 5e-13,   Method: Compositional matrix adjust.
 Identities = 53/202 (26%), Positives = 95/202 (47%), Gaps = 6/202 (2%)
 Frame = +2

Query: 4446 LRTLINELVKGILPRSWSHYTVPAGMTVIQWVSDFSERIKQLQNISQAAASGGAKELKNI 4505
            +  L N L   ++P +WS    P+  T+  W +D  +RIK+L+  +       A      
Sbjct: 2    MEALSNALFLDVVPDNWSKRAYPSLFTLGLWYADLLQRIKELETWTSDFQLPAA------ 163

Query: 4506 HVCLGGLFVPEAYITATRQYVAQANSWSLEELCLEVNVTASQSATLDAC---SFGVTGLK 4562
             V LGG F P++++TA  Q +A+ N W L+ + L+ +VT      +         V GL 
Sbjct: 164  -VWLGGFFNPQSFLTAIMQQMARKNEWPLDRMVLQCDVTKKSRDDMAGPPREGAYVHGLY 340

Query: 4563 LQGATCSNNKLSLSNA-ISTVLPLTQLRWVKQTSAEKK--ASVVTLPVYLNFTRADLIFT 4619
            ++GA        ++ A +  + P+  + ++K    +++   ++ + PVY   +R    F 
Sbjct: 341  MEGARWDTQTGMMAEARLKELAPIMPVLFIKAIPVDRQDVRNIYSCPVYKTKSRGP-TFV 517

Query: 4620 VDFEIATKEDPRSFYERGVAVL 4641
              F + TKE P  +   GVA+L
Sbjct: 518  WTFNLKTKEKPSKWILGGVAIL 583
>32781
          Length = 632

 Score = 70.9 bits (172), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 43/137 (31%), Positives = 67/137 (48%), Gaps = 7/137 (5%)
 Frame = -3

Query: 3480 LSAERERWEKTSETFKNQMSTIAGDCLLSAAFIAYAGYFDQQMRQNLFTTWSHHLQQANI 3539
            L++E  RW  + + F+    T+ GD L+  AF++Y G F  + R  LF T   HL     
Sbjct: 498  LASENVRWADSIQQFRINEQTLPGDVLMITAFVSYVGSFTXRYRTELFET---HLTPFLK 328

Query: 3540 QFRTDIARTEYLS------NADERLRWQASSLPADDLCTENAIMLKRFNRYPLIIDPSGQ 3593
              +  +  +E L       +  +   W    LP+D + TENA +L    R+PL+IDP  Q
Sbjct: 327  GLKYPVPVSEGLDPLTMLVDDADIAGWNNEGLPSDRMSTENATILTSCERWPLMIDPQLQ 148

Query: 3594 ATEFIMNEY-KDRKITR 3609
              ++I  +Y  D K+ R
Sbjct: 147  GIKWIKTKYGADLKVVR 97
>35288
          Length = 370

 Score = 57.8 bits (138), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 35/128 (27%), Positives = 65/128 (50%)
 Frame = +3

Query: 3480 LSAERERWEKTSETFKNQMSTIAGDCLLSAAFIAYAGYFDQQMRQNLFTTWSHHLQQANI 3539
            L  E +RW +       ++  +    LL+AAFI Y     + +R+     W   +  A+ 
Sbjct: 3    LDGEYQRWNEQVGELTKELQELPLRALLAAAFITYLPSAPEDLRREYMKAWMDAIGIAHF 182

Query: 3540 QFRTDIARTEYLSNADERLRWQASSLPADDLCTENAIMLKRFNRYPLIIDPSGQATEFIM 3599
              R       +LS   E+L W+A  LP+D+L  ENA+++ + ++ P ++DPS +AT ++ 
Sbjct: 183  DLR------RFLSTESEQLTWKAEGLPSDELSMENALVILQSSQRPFLVDPSSRATXWLK 344

Query: 3600 NEYKDRKI 3607
               K+ ++
Sbjct: 345  VHMKNNRL 368
>06548
          Length = 1130

 Score = 55.5 bits (132), Expect = 5e-07,   Method: Compositional matrix adjust.
 Identities = 48/195 (24%), Positives = 86/195 (44%), Gaps = 10/195 (5%)
 Frame = -2

Query: 4458 LPRSWSHYTVPAGMTVIQWVSDFSERIKQLQNISQAAASGGAKELKNIHVCLGGLFVPEA 4517
            +P +W   +  +  T+  W +D  +R  Q         +    E + +   + G F P+ 
Sbjct: 1048 VPNTWKKISWESA-TLGFWFTDLLDRNTQF--------NAWLFEGRPVSFWMTGFFNPQG 896

Query: 4518 YITATRQYVAQAN-SWSLEELCLEVNVTASQSATLDAC---SFGVTGLKLQGATCSNNKL 4573
            ++TA RQ + +A+  W+L+ + L+ +VT      + +       V GL L GA       
Sbjct: 895  FLTAMRQEITRAHKGWALDTVILDNDVTRMMKEDVHSPPGEGVYVHGLFLDGAGWERRNA 716

Query: 4574 SL----SNAISTVLPLTQLRWVKQTSAEKKAS--VVTLPVYLNFTRADLIFTVDFEIATK 4627
             L    +  + T+LP+     +  T+ EK+ S  +   PVY    R DL +     + T 
Sbjct: 715  RLIEPTAKVLYTLLPVVH---ISATNVEKQRSMNLYECPVYKKPKRTDLTYIFPLMLKTN 545

Query: 4628 EDPRSFYERGVAVLC 4642
            ++P  +  RGV +LC
Sbjct: 544  KNPDYWTLRGVGLLC 500
>20268
          Length = 416

 Score = 43.9 bits (102), Expect = 0.002,   Method: Composition-based stats.
 Identities = 20/68 (29%), Positives = 39/68 (57%)
 Frame = -1

Query: 1611 KALGEYLERERSSFPRFYFVGDEDLLEIIGNSKNVAKLQKHFKKMFAGVSSIILNEDNSV 1670
            K+L  YL+ +R +FPRFYFV D  LL ++    ++  ++ H + +F  +  + L + +  
Sbjct: 242  KSLMGYLDNKRRAFPRFYFVSDNILLALLSRPNDLDSVRPHLRSIFMQLHDVKLEKAHEH 63

Query: 1671 VLGISSRE 1678
            +L  +S +
Sbjct: 62   ILDDNSSD 39
>13559
          Length = 1151

 Score = 41.6 bits (96), Expect = 0.008,   Method: Composition-based stats.
 Identities = 23/59 (38%), Positives = 35/59 (59%), Gaps = 4/59 (6%)
 Frame = -2

Query: 3583 RYPLIIDPSGQATEFIMNEYKD----RKITRTSFLDDAFRKNLESALRFGNPLLVQDVE 3637
            ++PLIIDP+GQA+ F+   Y+D      I  T   ++  R  +  ALRFG PL++  +E
Sbjct: 1078 KWPLIIDPTGQASTFL--RYRDTNYINAIRPTDMEEERARMAILGALRFGKPLVLDMME 908
>25583
          Length = 434

 Score = 40.0 bits (92), Expect = 0.020,   Method: Composition-based stats.
 Identities = 16/43 (37%), Positives = 27/43 (62%)
 Frame = -1

Query: 3161 KRGGRTMAITPRHYLDFINHYANLFHEKRSELEEQQMHLNVGL 3203
            +R  R+  +TP+ YL F+N Y N++ +K+ E+ E    +N GL
Sbjct: 413  QRYRRSTHVTPKSYLSFLNSYKNVYKQKKDEIGELANRMNTGL 285
>31256
          Length = 351

 Score = 34.7 bits (78), Expect = 0.94,   Method: Composition-based stats.
 Identities = 16/50 (32%), Positives = 25/50 (50%)
 Frame = -2

Query: 4593 QTSAEKKASVVTLPVYLNFTRADLIFTVDFEIATKEDPRSFYERGVAVLC 4642
            + +A     + T P+Y    R DL +  D  + T + P  +  RGVA+LC
Sbjct: 233  KDTAPPDTRMYTCPIYKKPRRTDLTYIADVMLRTTQSPDHWILRGVALLC 84
>30327
          Length = 563

 Score = 33.9 bits (76), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 33/121 (27%), Positives = 57/121 (47%), Gaps = 11/121 (9%)
 Frame = +1

Query: 3581 FNRYPLIIDPSGQATEFIMNEYKDRKITRTSFLDDAFRKNLESALRFGNPLLVQ----DV 3636
            F RY    D +    + I + ++D+K+T T+F+D   +K  +   + G P+ +Q      
Sbjct: 1    FRRYKSTEDQTTHLAQVIEDAFQDQKVTLTAFID--LQKAFDKVWKDGLPVKLQRSGIHG 174

Query: 3637 ESYDPVLNPVLNREVR-----RTGGRVLITLG-DQDIDLSPS-FVIFLSTRDPTVEFPPD 3689
              Y      + NR  R     R G +VL+  G  Q   LSP+ F++F++      +F P+
Sbjct: 175  NMYRWTKAYLYNRRARVLVNGRYGRKVLLRQGVPQGGVLSPTLFILFMN------DFVPE 336

Query: 3690 L 3690
            L
Sbjct: 337  L 339
>00810
          Length = 1431

 Score = 33.1 bits (74), Expect = 2.7,   Method: Compositional matrix adjust.
 Identities = 48/187 (25%), Positives = 72/187 (38%), Gaps = 11/187 (5%)
 Frame = -3

Query: 2571 DTVRHEALLYTWLAEHKPLVLCGPPGSGKTMTLFSALRALPDMEVVGLNFSSATTPELLL 2630
            D  RH +LL       K ++L GPPG GKTM +  A         + L  SS        
Sbjct: 1372 DLFRHSSLLQP----PKGVLLHGPPGCGKTM-IAKATAKAAGARFINLQVSSLVD----- 1223

Query: 2631 KTFDHYCEYRRTPNGVVLAPVQLGKWLVLFCDEINLPDMDKYGTQRVISFIRQMV----E 2686
                 Y E ++    V    ++L +  ++F DEI+             SF+R       E
Sbjct: 1222 ---KWYGESQKRAEAVFSLAIKL-QPTIIFIDEID-------------SFLRSRTSTDHE 1094

Query: 2687 HGGFYRTSDQT-WVKLE-----RIQFVGACNPPTDPGRKPLSHRFLRHVPVVY-VDYPGP 2739
                 +T   + W  L      R+  +GA N P D     +    LR +P ++ +  PGP
Sbjct: 1093 ATAMIKTQFMSFWDGLMTDPDCRVMVMGATNRPQD-----VDAAILRRMPSMFHIGLPGP 929

Query: 2740 ASLTQIY 2746
            A    I+
Sbjct: 928  AQRRSIF 908
>15303
          Length = 479

 Score = 33.1 bits (74), Expect = 3.0,   Method: Composition-based stats.
 Identities = 19/44 (43%), Positives = 25/44 (56%), Gaps = 1/44 (2%)
 Frame = -3

Query: 4366 STSDGRPAWM-RTLHTTASNWLHLIPQTLSPLKRTVENIKDPLF 4408
            S SDGR  ++   LHT     LHL+P +   LKR V ++K  LF
Sbjct: 360  SWSDGRYIFLIHLLHTVRLQNLHLLPHSPKRLKRVVLHVKHTLF 229
>05344
          Length = 1178

 Score = 32.3 bits (72), Expect = 4.0,   Method: Composition-based stats.
 Identities = 24/86 (27%), Positives = 44/86 (51%), Gaps = 7/86 (8%)
 Frame = +3

Query: 1722 VEIFGKATSIDPN--TYITWI-DKYQAQLVVLSAQIAWSENVENALSNVGG----GGDVG 1774
            + IF +++S +P+  +  +WI   Y+    +LS  ++ S+N+ NAL            VG
Sbjct: 477  MRIFTESSSTEPSYASSTSWIISSYE*HGCLLSGSVS*SKNLSNALPVPSAIRLTDRTVG 656

Query: 1775 PLQSVLSNVEVTLNVLADSVLMEQPP 1800
            P  S+L + + +L  LA  + +  PP
Sbjct: 657  PAMSILISFDTSLGKLAAYMNVSAPP 734
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|24418919|ref|NP_722476.1| brain glycogen
phosphorylase [Mus musculus]
         (843 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

18438                                                                 154   1e-66
19923                                                                 234   1e-61
04115                                                                  30   4.1  
>18438
          Length = 457

 Score =  154 bits (390), Expect(2) = 1e-66,   Method: Compositional matrix adjust.
 Identities = 74/101 (73%), Positives = 83/101 (82%), Gaps = 1/101 (0%)
 Frame = -1

Query: 192 KARPEYMLPVHFYGR-VEHTPDGVLWLDTQVVLAMPYDTPVPGYKNNTVNTMRLWSAKAP 250
           KARPEYMLPV+FYGR V+   D + W+DTQVVLAMPYDTP+PGY NNTVNT+RLWSA+AP
Sbjct: 457 KARPEYMLPVNFYGRCVQDGDDRIKWVDTQVVLAMPYDTPIPGYGNNTVNTLRLWSARAP 278

Query: 251 NDFKLKDFNVGDYIEAVLDRNLAENISRVLYPNDNFFEGKE 291
           N F L  FN G+YI AV DRNLAENISRVLYPNDNF   + 
Sbjct: 277 NSFNLHFFNSGEYITAVCDRNLAENISRVLYPNDNFSRARN 155

 Score =  117 bits (294), Expect(2) = 1e-66,   Method: Composition-based stats.
 Identities = 54/57 (94%), Positives = 56/57 (98%)
 Frame = -3

Query: 286 FFEGKELRLKQEYFVVAATLQDIIRRFKSSRFGCRDPVRTCFETFPDKVAIQLNDTH 342
           FFEGKELRLKQEYF+VAATLQDIIRRFKSSRFGCRDPVRT F+TFPDKVAIQLNDTH
Sbjct: 173 FFEGKELRLKQEYFLVAATLQDIIRRFKSSRFGCRDPVRTSFDTFPDKVAIQLNDTH 3
>19923
          Length = 471

 Score =  234 bits (597), Expect = 1e-61,   Method: Compositional matrix adjust.
 Identities = 104/156 (66%), Positives = 136/156 (87%)
 Frame = +3

Query: 508 IGEGFLTDLSQLKKLLSLVDDEAFIRDVAKVKQENKLKFSAQLEKEYKVKINPASMFDVH 567
           IGE ++T+L++L++L  L  +E  +R + KVKQENK+K +A +E+ Y VK NPASMFD+ 
Sbjct: 3   IGETWVTNLAELRRLEPLSKEETLLRSIMKVKQENKMKLTAYMEQNYGVKANPASMFDMQ 182

Query: 568 VKRIHEYKRQLLNCLHIITLYNRIKKDPAKAFVPRTVMIGGKAAPGYHMAKMIIKLVTSI 627
           VKRIHEYKRQL+NCLH+IT+YNRIKK+P+  FVPRTVMIGGKAAPGYHMAK+IIKL+ ++
Sbjct: 183 VKRIHEYKRQLMNCLHVITIYNRIKKNPSIPFVPRTVMIGGKAAPGYHMAKLIIKLINNV 362

Query: 628 GDVVNHDPVVGDRLRVIFLENYRVSLAEKVIPAADL 663
           G  +N+DP+VGDRL++++LENYRVSLAEK+IPAADL
Sbjct: 363 GRTINNDPIVGDRLKLVYLENYRVSLAEKIIPAADL 470
>04115
          Length = 2897

 Score = 30.0 bits (66), Expect = 4.1,   Method: Composition-based stats.
 Identities = 9/15 (60%), Positives = 14/15 (93%)
 Frame = +3

Query: 825 IWGVEPSDLQIPPPN 839
           IWGVEP+D+++P P+
Sbjct: 3   IWGVEPTDIKLPAPH 47
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31981302|ref|NP_038500.2| annexin A6 isoform a [Mus
musculus]
         (673 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

32521                                                                 249   2e-66
06659                                                                 160   1e-39
36934                                                                 135   6e-32
22178                                                                 100   2e-27
12136                                                                  85   1e-16
17882                                                                  67   9e-16
13827                                                                  62   2e-11
29756                                                                  55   9e-08
>32521
          Length = 1241

 Score =  249 bits (637), Expect = 2e-66,   Method: Compositional matrix adjust.
 Identities = 127/270 (47%), Positives = 181/270 (67%)
 Frame = +2

Query: 53  KQRQEICQNYKSLYGKDLIEDLKYELTGKFERLIVNLMRPLAYCDAKEIKDAISGVGTDE 112
           +QR+EI   YK+++GKDL ++L  EL+G F+ L V ++   A  DAK+I  A+ G+GTDE
Sbjct: 2   EQRREINLTYKTMFGKDLGKELSGELSGNFKTLCVEMLLGPAEFDAKQINKAVKGLGTDE 181

Query: 113 KCLIEILASRTNEQMHQLVAAYKDAYERDLESDIIGDTSGHFQKMLVVLLQGTRENDDVV 172
           + LIEI+ +RTN Q+  +  AYK  Y++D+E+DI GDTSG F+++L+  LQ  R      
Sbjct: 182 RALIEIICTRTNAQLTAMKEAYKTMYQKDVETDIEGDTSGPFKRLLIGCLQANRPEGQEF 361

Query: 173 SEDLVQQDVQDLYEAGELKWGTDEAQFIYILGNRSKQHLRLVFDEYLKTTGKPIEASIRG 232
             +  +QD Q L EAGE KWGTDE++F  ++ +RS   LR  F EY K   K IE SI  
Sbjct: 362 DRNKAKQDAQALLEAGEKKWGTDESRFNVVIVSRSFPQLRATFQEYAKLANKDIEDSISS 541

Query: 233 ELSGDFEKLMLAVVKCIRSTPEYFAERLFKAMKGLGTRDNTLIRIMVSRSELDMLDIREI 292
           E+SGD +  ML VV+ IRS   +FA  L +AMKGLGT D+TL+R++ SR E+DM+ I+E 
Sbjct: 542 EMSGDXKNGMLTVVRVIRSKATHFATELHRAMKGLGTDDDTLVRVVASRCEVDMVQIKEE 721

Query: 293 FRTKYEKSLYSMIKNDTSGEYKKALLKLCG 322
           F+  ++++LYS I +DTSG+Y+  L  L G
Sbjct: 722 FQRNFKQTLYSFIVDDTSGDYRLMLCNLIG 811

 Score =  225 bits (574), Expect = 3e-59,   Method: Compositional matrix adjust.
 Identities = 116/274 (42%), Positives = 171/274 (62%)
 Frame = +2

Query: 397 QRQQIRQTFKSHFGRDLMADLKSEISGDLARLILGLMMPPAHYDAKQLKKAMEGAGTDEK 456
           QR++I  T+K+ FG+DL  +L  E+SG+   L + +++ PA +DAKQ+ KA++G GTDE+
Sbjct: 5   QRREINLTYKTMFGKDLGKELSGELSGNFKTLCVEMLLGPAEFDAKQINKAVKGLGTDER 184

Query: 457 TLIEILATRTNAEIRAINEAYKEDYHKSLEDALSSDTSGHFRRILISLATGNREEGGENR 516
            LIEI+ TRTNA++ A+ EAYK  Y K +E  +  DTSG F+R+LI     NR EG E  
Sbjct: 185 ALIEIICTRTNAQLTAMKEAYKTMYQKDVETDIEGDTSGPFKRLLIGCLQANRPEGQE-- 358

Query: 517 XXXXXXXXXXXXILEIADTPSGDKTSLETRFMTVLCTRSYPHLRRVFQEFIKKTNYDIEH 576
                       +LE  +   G   + E+RF  V+ +RS+P LR  FQE+ K  N DIE 
Sbjct: 359 FDRNKAKQDAQALLEAGEKKWG---TDESRFNVVIVSRSFPQLRATFQEYAKLANKDIED 529

Query: 577 VIKKEMSGDVKDAFVAIVQSVKNKPLFFADKLYKSMKGAGTDEKTLTRVMVSRSEIDLLN 636
            I  EMSGD K+  + +V+ +++K   FA +L+++MKG GTD+ TL RV+ SR E+D++ 
Sbjct: 530 SISSEMSGDXKNGMLTVVRVIRSKATHFATELHRAMKGLGTDDDTLVRVVASRCEVDMVQ 709

Query: 637 IRREFIEKYDKSLHQAIEGDTSGDFMKALLALCG 670
           I+ EF   + ++L+  I  DTSGD+   L  L G
Sbjct: 710 IKEEFQRNFKQTLYSFIVDDTSGDYRLMLCNLIG 811

 Score = 84.7 bits (208), Expect = 1e-16,   Method: Compositional matrix adjust.
 Identities = 52/170 (30%), Positives = 95/170 (55%), Gaps = 16/170 (9%)
 Frame = +2

Query: 352 ELKG---TVCAANDFNP-DADAKALRKAMKGIGTDEATIIDIVTHRSNAQRQQIRQTFKS 407
           EL G   T+C      P + DAK + KA+KG+GTDE  +I+I+  R+NAQ   +++ +K+
Sbjct: 74  ELSGNFKTLCVEMLLGPAEFDAKQINKAVKGLGTDERALIEIICTRTNAQLTAMKEAYKT 253

Query: 408 HFGRDLMADLKSEISGDLARLILGLMMP-----------PAHYDAKQLKKAMEGA-GTDE 455
            + +D+  D++ + SG   RL++G +              A  DA+ L +A E   GTDE
Sbjct: 254 MYQKDVETDIEGDTSGPFKRLLIGCLQANRPEGQEFDRNKAKQDAQALLEAGEKKWGTDE 433

Query: 456 KTLIEILATRTNAEIRAINEAYKEDYHKSLEDALSSDTSGHFRRILISLA 505
                ++ +R+  ++RA  + Y +  +K +ED++SS+ SG  +  ++++ 
Sbjct: 434 SRFNVVIVSRSFPQLRATFQEYAKLANKDIEDSISSEMSGDXKNGMLTVV 583

 Score = 70.9 bits (172), Expect = 1e-12,   Method: Compositional matrix adjust.
 Identities = 58/238 (24%), Positives = 119/238 (50%), Gaps = 12/238 (5%)
 Frame = +2

Query: 19  EFDANQDAEALYTAMKGFGSDKESILELITSRSNKQRQEICQNYKSLYGKDLIEDLKYEL 78
           EFDA Q    +  A+KG G+D+ +++E+I +R+N Q   + + YK++Y KD+  D++ + 
Sbjct: 128 EFDAKQ----INKAVKGLGTDERALIEIICTRTNAQLTAMKEAYKTMYQKDVETDIEGDT 295

Query: 79  TGKFERLIVNLM-----------RPLAYCDAKEIKDA-ISGVGTDEKCLIEILASRTNEQ 126
           +G F+RL++  +           R  A  DA+ + +A     GTDE     ++ SR+  Q
Sbjct: 296 SGPFKRLLIGCLQANRPEGQEFDRNKAKQDAQALLEAGEKKWGTDESRFNVVIVSRSFPQ 475

Query: 127 MHQLVAAYKDAYERDLESDIIGDTSGHFQKMLVVLLQGTRENDDVVSEDLVQQDVQDLYE 186
           +      Y     +D+E  I  + SG  +  ++ +++  R      + +L  + ++ L  
Sbjct: 476 LRATFQEYAKLANKDIEDSISSEMSGDXKNGMLTVVRVIRSKATHFATEL-HRAMKGL-- 646

Query: 187 AGELKWGTDEAQFIYILGNRSKQHLRLVFDEYLKTTGKPIEASIRGELSGDFEKLMLA 244
                 GTD+   + ++ +R +  +  + +E+ +   + + + I  + SGD+ +LML 
Sbjct: 647 ------GTDDDTLVRVVASRCEVDMVQIKEEFQRNFKQTLYSFIVDDTSGDY-RLMLC 799

 Score = 32.0 bits (71), Expect = 0.81,   Method: Compositional matrix adjust.
 Identities = 16/69 (23%), Positives = 37/69 (53%)
 Frame = +2

Query: 22  ANQDAEALYTAMKGFGSDKESILELITSRSNKQRQEICQNYKSLYGKDLIEDLKYELTGK 81
           A   A  L+ AMKG G+D ++++ ++ SR      +I + ++  + + L   +  + +G 
Sbjct: 602 ATHFATELHRAMKGLGTDDDTLVRVVASRCEVDMVQIKEEFQRNFKQTLYSFIVDDTSGD 781

Query: 82  FERLIVNLM 90
           +  ++ NL+
Sbjct: 782 YRLMLCNLI 808
>06659
          Length = 776

 Score =  160 bits (406), Expect = 1e-39,   Method: Compositional matrix adjust.
 Identities = 96/223 (43%), Positives = 138/223 (61%), Gaps = 3/223 (1%)
 Frame = -3

Query: 101 IKDAISGVGTDEKCLIEILASRTNEQMHQLVAAYKDAYERDLESDIIGDTSGHFQKMLVV 160
           + DAISG GTDEKCLI+I+ +R N++M ++   YK+ +E +LE D+  DT G+F+++++ 
Sbjct: 774 LHDAISGAGTDEKCLIDIMCTRDNDEMKEIKEKYKEEFESELEEDLQADTGGYFRRLMIS 595

Query: 161 LLQGTRENDD--VVSEDLVQQDVQDLYEAGELKWGTDEAQFIYILGNRSKQHLRLVFDEY 218
           L  G R+ D+    +ED   +D Q   EAGE  WGT+EA    IL   S   L    ++Y
Sbjct: 594 LCVGGRDYDNWWXANEDKAVEDAQKFLEAGENAWGTEEADMNAILCRTSPAQLCKTIEKY 415

Query: 219 LK-TTGKPIEASIRGELSGDFEKLMLAVVKCIRSTPEYFAERLFKAMKGLGTRDNTLIRI 277
            + T GK +E SIR E S D     LA+V+  RS P YFA RL     GLGT DN LIRI
Sbjct: 414 EELTEGKTMEESIRSECSDDLXDGYLAIVESARSMPRYFARRLNDCFSGLGTSDNDLIRI 235

Query: 278 MVSRSELDMLDIREIFRTKYEKSLYSMIKNDTSGEYKKALLKL 320
           +VSRSE+D+  I++ +   YEK L   ++++  G+YK+ LL +
Sbjct: 234 IVSRSEVDLEAIKQAYEEMYEKPLTEAVESECGGDYKRLLLAI 106

 Score =  125 bits (314), Expect = 6e-29,   Method: Compositional matrix adjust.
 Identities = 82/226 (36%), Positives = 127/226 (56%), Gaps = 1/226 (0%)
 Frame = -3

Query: 444 LKKAMEGAGTDEKTLIEILATRTNAEIRAINEAYKEDYHKSLEDALSSDTSGHFRRILIS 503
           L  A+ GAGTDEK LI+I+ TR N E++ I E YKE++   LE+ L +DT G+FRR++IS
Sbjct: 774 LHDAISGAGTDEKCLIDIMCTRDNDEMKEIKEKYKEEFESELEEDLQADTGGYFRRLMIS 595

Query: 504 LATGNREEGGENRXXXXXXXXXXXXILEIADTPSGDKTSLETRFMTVLCTRSYPHLRRVF 563
           L  G R+                   LE  +   G +   E     +LC  S   L +  
Sbjct: 594 LCVGGRDYDNWWXANEDKAVEDAQKFLEAGENAWGTE---EADMNAILCRTSPAQLCKTI 424

Query: 564 QEFIKKT-NYDIEHVIKKEMSGDVKDAFVAIVQSVKNKPLFFADKLYKSMKGAGTDEKTL 622
           +++ + T    +E  I+ E S D+ D ++AIV+S ++ P +FA +L     G GT +  L
Sbjct: 423 EKYEELTEGKTMEESIRSECSDDLXDGYLAIVESARSMPRYFARRLNDCFSGLGTSDNDL 244

Query: 623 TRVMVSRSEIDLLNIRREFIEKYDKSLHQAIEGDTSGDFMKALLAL 668
            R++VSRSE+DL  I++ + E Y+K L +A+E +  GD+ + LLA+
Sbjct: 243 IRIIVSRSEVDLEAIKQAYEEMYEKPLTEAVESECGGDYKRLLLAI 106

 Score = 46.6 bits (109), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 53/234 (22%), Positives = 110/234 (47%), Gaps = 15/234 (6%)
 Frame = -3

Query: 29  LYTAMKGFGSDKESILELITSRSNKQRQEICQNYKSLYGKDLIEDLKYELTGKFERLIVN 88
           L+ A+ G G+D++ +++++ +R N + +EI + YK  +  +L EDL+ +  G F RL+++
Sbjct: 774 LHDAISGAGTDEKCLIDIMCTRDNDEMKEIKEKYKEEFESELEEDLQADTGGYFRRLMIS 595

Query: 89  LM-------RPLAYCDAKEIKDAI-------SGVGTDEKCLIEILASRTNEQMHQLVAAY 134
           L              + K ++DA        +  GT+E  +  IL   +  Q+ + +  Y
Sbjct: 594 LCVGGRDYDNWWXANEDKAVEDAQKFLEAGENAWGTEEADMNAILCRTSPAQLCKTIEKY 415

Query: 135 KDAYE-RDLESDIIGDTSGHFQKMLVVLLQGTRENDDVVSEDLVQQDVQDLYEAGELKWG 193
           ++  E + +E  I  + S       + +++  R      +  L      D +       G
Sbjct: 414 EELTEGKTMEESIRSECSDDLXDGYLAIVESARSMPRYFARRL-----NDCFSG----LG 262

Query: 194 TDEAQFIYILGNRSKQHLRLVFDEYLKTTGKPIEASIRGELSGDFEKLMLAVVK 247
           T +   I I+ +RS+  L  +   Y +   KP+  ++  E  GD+++L+LA++ 
Sbjct: 261 TSDNDLIRIIVSRSEVDLEAIKQAYEEMYEKPLTEAVESECGGDYKRLLLAILN 100

 Score = 46.6 bits (109), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 35/147 (23%), Positives = 72/147 (48%), Gaps = 5/147 (3%)
 Frame = -3

Query: 22  ANQDAEALYTAMK-GFGSDKESILELITSRSNKQRQEICQNYKSLY-GKDLIEDLKYELT 79
           A +DA+    A +  +G+++  +  ++   S  Q  +  + Y+ L  GK + E ++ E +
Sbjct: 540 AVEDAQKFLEAGENAWGTEEADMNAILCRTSPAQLCKTIEKYEELTEGKTMEESIRSECS 361

Query: 80  GKFER---LIVNLMRPLAYCDAKEIKDAISGVGTDEKCLIEILASRTNEQMHQLVAAYKD 136
                    IV   R +    A+ + D  SG+GT +  LI I+ SR+   +  +  AY++
Sbjct: 360 DDLXDGYLAIVESARSMPRYFARRLNDCFSGLGTSDNDLIRIIVSRSEVDLEAIKQAYEE 181

Query: 137 AYERDLESDIIGDTSGHFQKMLVVLLQ 163
            YE+ L   +  +  G ++++L+ +L 
Sbjct: 180 MYEKPLTEAVESECGGDYKRLLLAILN 100

 Score = 44.7 bits (104), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 59/245 (24%), Positives = 107/245 (43%), Gaps = 15/245 (6%)
 Frame = -3

Query: 372 LRKAMKGIGTDEATIIDIVTHRSNAQRQQIRQTFKSHFGRDLMADLKSEISGDLARLILG 431
           L  A+ G GTDE  +IDI+  R N + ++I++ +K  F  +L  DL+++  G   RL++ 
Sbjct: 774 LHDAISGAGTDEKCLIDIMCTRDNDEMKEIKEKYKEEFESELEEDLQADTGGYFRRLMIS 595

Query: 432 LMMPPAHY-------------DAKQLKKAMEGA-GTDEKTLIEILATRTNAEIRAINEAY 477
           L +    Y             DA++  +A E A GT+E  +  IL   + A++    E Y
Sbjct: 594 LCVGGRDYDNWWXANEDKAVEDAQKFLEAGENAWGTEEADMNAILCRTSPAQLCKTIEKY 415

Query: 478 KE-DYHKSLEDALSSDTSGHFRRILISLATGNREEGGENRXXXXXXXXXXXXILEIADTP 536
           +E    K++E+++ S+ S       +++    R                      + D  
Sbjct: 414 EELTEGKTMEESIRSECSDDLXDGYLAIVESAR-------------SMPRYFARRLNDCF 274

Query: 537 SGDKTSLETRFMTVLCTRSYPHLRRVFQEFIKKTNYDIEHVIKKEMSGDVKDAFVAIVQS 596
           SG  TS +   + ++ +RS   L  + Q + +     +   ++ E  GD K   +AI+  
Sbjct: 273 SGLGTS-DNDLIRIIVSRSEVDLEAIKQAYEEMYEKPLTEAVESECGGDYKRLLLAIL-- 103

Query: 597 VKNKP 601
             N P
Sbjct: 102 --NPP 94

 Score = 35.0 bits (79), Expect = 0.088,   Method: Compositional matrix adjust.
 Identities = 23/67 (34%), Positives = 43/67 (64%), Gaps = 1/67 (1%)
 Frame = -3

Query: 608 LYKSMKGAGTDEKTLTRVMVSRSEIDLLNIRREFIEKYDKSLHQAIEGDTSGDFMKALLA 667
           L+ ++ GAGTDEK L  +M +R   ++  I+ ++ E+++  L + ++ DT G F + +++
Sbjct: 774 LHDAISGAGTDEKCLIDIMCTRDNDEMKEIKEKYKEEFESELEEDLQADTGGYFRRLMIS 595

Query: 668 LC-GGED 673
           LC GG D
Sbjct: 594 LCVGGRD 574
>36934
          Length = 667

 Score =  135 bits (339), Expect = 6e-32,   Method: Compositional matrix adjust.
 Identities = 80/200 (40%), Positives = 116/200 (58%), Gaps = 1/200 (0%)
 Frame = +3

Query: 22  ANQDAEALYTAMKGFG-SDKESILELITSRSNKQRQEICQNYKSLYGKDLIEDLKYELTG 80
           A +DAE L+ AM G G + ++++LE+I  RSN QRQ + + YK +Y +DL E L+ ELTG
Sbjct: 18  AAEDAERLHKAMSGMGVTHEDTVLEIIIKRSNSQRQTLKKKYKEMYKRDLAEHLQSELTG 197

Query: 81  KFERLIVNLMRPLAYCDAKEIKDAISGVGTDEKCLIEILASRTNEQMHQLVAAYKDAYER 140
            FE LI+ L+ P    DA  +  A+ G+GT+E  LI IL +   +++  +   YK  Y  
Sbjct: 198 DFEELILGLLMPPVEYDAFCLNKAVDGLGTNEDVLIGILCTANPKELSSVKEVYKKTYGE 377

Query: 141 DLESDIIGDTSGHFQKMLVVLLQGTRENDDVVSEDLVQQDVQDLYEAGELKWGTDEAQFI 200
           DL+S I GDTSG F+ +L+ L +G R+    V+E   +QD Q L    + K G     F 
Sbjct: 378 DLDSAIKGDTSGGFEDLLLALSRGERDQSKSVNEKEAKQDAQKLCPDKK*KTGHG**NFQ 557

Query: 201 YILGNRSKQHLRLVFDEYLK 220
           YI    +KQ ++  F EY K
Sbjct: 558 YIDDKENKQQMKATFVEYEK 617

 Score =  134 bits (336), Expect = 1e-31,   Method: Compositional matrix adjust.
 Identities = 66/145 (45%), Positives = 98/145 (67%), Gaps = 1/145 (0%)
 Frame = +3

Query: 368 DAKALRKAMKGIG-TDEATIIDIVTHRSNAQRQQIRQTFKSHFGRDLMADLKSEISGDLA 426
           DA+ L KAM G+G T E T+++I+  RSN+QRQ +++ +K  + RDL   L+SE++GD  
Sbjct: 27  DAERLHKAMSGMGVTHEDTVLEIIIKRSNSQRQTLKKKYKEMYKRDLAEHLQSELTGDFE 206

Query: 427 RLILGLMMPPAHYDAKQLKKAMEGAGTDEKTLIEILATRTNAEIRAINEAYKEDYHKSLE 486
            LILGL+MPP  YDA  L KA++G GT+E  LI IL T    E+ ++ E YK+ Y + L+
Sbjct: 207 ELILGLLMPPVEYDAFCLNKAVDGLGTNEDVLIGILCTANPKELSSVKEVYKKTYGEDLD 386

Query: 487 DALSSDTSGHFRRILISLATGNREE 511
            A+  DTSG F  +L++L+ G R++
Sbjct: 387 SAIKGDTSGGFEDLLLALSRGERDQ 461

 Score = 58.9 bits (141), Expect = 7e-09,   Method: Compositional matrix adjust.
 Identities = 43/177 (24%), Positives = 83/177 (46%), Gaps = 1/177 (0%)
 Frame = +3

Query: 257 AERLFKAMKGLG-TRDNTLIRIMVSRSELDMLDIREIFRTKYEKSLYSMIKNDTSGEYKK 315
           AERL KAM G+G T ++T++ I++ RS      +++ ++  Y++ L   ++++ +G++++
Sbjct: 30  AERLHKAMSGMGVTHEDTVLEIIIKRSNSQRQTLKKKYKEMYKRDLAEHLQSELTGDFEE 209

Query: 316 ALLKLCGGDDDAAGQFFPEAAQVAYQMWELSAVSRVELKGTVCAANDFNPDADAKALRKA 375
            +L          G   P    V Y                           DA  L KA
Sbjct: 210 LIL----------GLLMP---PVEY---------------------------DAFCLNKA 269

Query: 376 MKGIGTDEATIIDIVTHRSNAQRQQIRQTFKSHFGRDLMADLKSEISGDLARLILGL 432
           + G+GT+E  +I I+   +  +   +++ +K  +G DL + +K + SG    L+L L
Sbjct: 270 VDGLGTNEDVLIGILCTANPKELSSVKEVYKKTYGEDLDSAIKGDTSGGFEDLLLAL 440

 Score = 52.0 bits (123), Expect = 8e-07,   Method: Compositional matrix adjust.
 Identities = 37/139 (26%), Positives = 71/139 (51%), Gaps = 3/139 (2%)
 Frame = +3

Query: 537 SGDKTSLETRFMTVLCTRSYPH---LRRVFQEFIKKTNYDIEHVIKKEMSGDVKDAFVAI 593
           SG   + E   + ++  RS      L++ ++E  K+   D+   ++ E++GD ++  + +
Sbjct: 54  SGMGVTHEDTVLEIIIKRSNSQRQTLKKKYKEMYKR---DLAEHLQSELTGDFEELILGL 224

Query: 594 VQSVKNKPLFFADKLYKSMKGAGTDEKTLTRVMVSRSEIDLLNIRREFIEKYDKSLHQAI 653
           +        F    L K++ G GT+E  L  ++ + +  +L +++  + + Y + L  AI
Sbjct: 225 LMPPVEYDAFC---LNKAVDGLGTNEDVLIGILCTANPKELSSVKEVYKKTYGEDLDSAI 395

Query: 654 EGDTSGDFMKALLALCGGE 672
           +GDTSG F   LLAL  GE
Sbjct: 396 KGDTSGGFEDLLLALSRGE 452
>22178
          Length = 655

 Score =  100 bits (248), Expect(2) = 2e-27,   Method: Compositional matrix adjust.
 Identities = 48/81 (59%), Positives = 62/81 (76%)
 Frame = +1

Query: 590 FVAIVQSVKNKPLFFADKLYKSMKGAGTDEKTLTRVMVSRSEIDLLNIRREFIEKYDKSL 649
           F+AIV+  +N P +FA++LYKSMKGAGT++K L R +VSRSE DL  I++EF   Y K+L
Sbjct: 217 FLAIVRVARNTPAYFAERLYKSMKGAGTNDKALIRAIVSRSENDLGFIKQEFQRMYGKTL 396

Query: 650 HQAIEGDTSGDFMKALLALCG 670
              I+GDTSGD+ K LLALCG
Sbjct: 397 ASYIKGDTSGDYKKILLALCG 459

 Score = 41.2 bits (95), Expect(2) = 2e-27,   Method: Compositional matrix adjust.
 Identities = 19/47 (40%), Positives = 27/47 (57%)
 Frame = +2

Query: 544 ETRFMTVLCTRSYPHLRRVFQEFIKKTNYDIEHVIKKEMSGDVKDAF 590
           E  F  +LC R+Y  LR  F  + + +  DIE  IK EMSG+++  F
Sbjct: 77  EETFNRILCLRNYGQLRATFDAYRQISGKDIEDAIKSEMSGNLEAGF 217

 Score = 98.6 bits (244), Expect = 7e-21,   Method: Compositional matrix adjust.
 Identities = 49/82 (59%), Positives = 61/82 (74%)
 Frame = +1

Query: 241 LMLAVVKCIRSTPEYFAERLFKAMKGLGTRDNTLIRIMVSRSELDMLDIREIFRTKYEKS 300
           L LA+V+  R+TP YFAERL+K+MKG GT D  LIR +VSRSE D+  I++ F+  Y K+
Sbjct: 214 LFLAIVRVARNTPAYFAERLYKSMKGAGTNDKALIRAIVSRSENDLGFIKQEFQRMYGKT 393

Query: 301 LYSMIKNDTSGEYKKALLKLCG 322
           L S IK DTSG+YKK LL LCG
Sbjct: 394 LASYIKGDTSGDYKKILLALCG 459

 Score = 43.1 bits (100), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 21/64 (32%), Positives = 40/64 (62%)
 Frame = +1

Query: 26  AEALYTAMKGFGSDKESILELITSRSNKQRQEICQNYKSLYGKDLIEDLKYELTGKFERL 85
           AE LY +MKG G++ ++++  I SRS      I Q ++ +YGK L   +K + +G ++++
Sbjct: 262 AERLYKSMKGAGTNDKALIRAIVSRSENDLGFIKQEFQRMYGKTLASYIKGDTSGDYKKI 441

Query: 86  IVNL 89
           ++ L
Sbjct: 442 LLAL 453

 Score = 40.8 bits (94), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 20/49 (40%), Positives = 30/49 (61%)
 Frame = +2

Query: 449 EGAGTDEKTLIEILATRTNAEIRAINEAYKEDYHKSLEDALSSDTSGHF 497
           E  GTDE+T   IL  R   ++RA  +AY++   K +EDA+ S+ SG+ 
Sbjct: 59  ESVGTDEETFNRILCLRNYGQLRATFDAYRQISGKDIEDAIKSEMSGNL 205

 Score = 30.4 bits (67), Expect = 2.4,   Method: Compositional matrix adjust.
 Identities = 16/47 (34%), Positives = 27/47 (57%)
 Frame = +2

Query: 379 IGTDEATIIDIVTHRSNAQRQQIRQTFKSHFGRDLMADLKSEISGDL 425
           +GTDE T   I+  R+  Q +     ++   G+D+   +KSE+SG+L
Sbjct: 65  VGTDEETFNRILCLRNYGQLRATFDAYRQISGKDIEDAIKSEMSGNL 205

 Score = 29.6 bits (65), Expect = 4.3,   Method: Compositional matrix adjust.
 Identities = 16/48 (33%), Positives = 24/48 (50%)
 Frame = +2

Query: 108 VGTDEKCLIEILASRTNEQMHQLVAAYKDAYERDLESDIIGDTSGHFQ 155
           VGTDE+    IL  R   Q+     AY+    +D+E  I  + SG+ +
Sbjct: 65  VGTDEETFNRILCLRNYGQLRATFDAYRQISGKDIEDAIKSEMSGNLE 208
>12136
          Length = 445

 Score = 84.7 bits (208), Expect = 1e-16,   Method: Compositional matrix adjust.
 Identities = 46/111 (41%), Positives = 68/111 (61%), Gaps = 7/111 (6%)
 Frame = +3

Query: 413 LMADLKSEISGDLARLILGLMMPPAHYDAKQLKKAMEGAGTDEKTLIEILATRTNAEIRA 472
           L+ ++K E+SGD   L++ L + PA YDA  +K+A+ G GTDE  L+EIL TRTNA+I+ 
Sbjct: 3   LIEEIKGELSGDYKELVMALFVAPAEYDAWCIKEAIYGPGTDEMALMEILMTRTNAQIKE 182

Query: 473 INEAYK----EDYH---KSLEDALSSDTSGHFRRILISLATGNREEGGENR 516
           +   Y     + YH     +E  +  D SG F+R+LIS + G R E  ++R
Sbjct: 183 LRSIYPSVLNDHYHGRTPKIEQDIEDDCSGDFKRLLISASQGGRFEIPKDR 335

 Score = 72.4 bits (176), Expect = 6e-13,   Method: Compositional matrix adjust.
 Identities = 52/139 (37%), Positives = 78/139 (56%), Gaps = 7/139 (5%)
 Frame = +3

Query: 70  LIEDLKYELTGKFERLIVNLMRPLAYCDAKEIKDAISGVGTDEKCLIEILASRTNEQMHQ 129
           LIE++K EL+G ++ L++ L    A  DA  IK+AI G GTDE  L+EIL +RTN Q+ +
Sbjct: 3   LIEEIKGELSGDYKELVMALFVAPAEYDAWCIKEAIYGPGTDEMALMEILMTRTNAQIKE 182

Query: 130 LVAAYK----DAYE---RDLESDIIGDTSGHFQKMLVVLLQGTRENDDVVSEDLVQQDVQ 182
           L + Y     D Y      +E DI  D SG F+++L+   QG R     + +D +++ V+
Sbjct: 183 LRSIYPSVLNDHYHGRTPKIEQDIEDDCSGDFKRLLISASQGGRFE---IPKDRLEESVE 353

Query: 183 DLYEAGELKWGTDEAQFIY 201
           ++    E K GT   Q  Y
Sbjct: 354 EILNP-ETKEGTGMFQVNY 407

 Score = 45.1 bits (105), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 28/101 (27%), Positives = 57/101 (56%), Gaps = 7/101 (6%)
 Frame = +3

Query: 230 IRGELSGDFEKLMLAVVKCIRSTPEYFAERLFKAMKGLGTRDNTLIRIMVSRSELDMLDI 289
           I+GELSGD+++L++A+     +  EY A  + +A+ G GT +  L+ I+++R+   + ++
Sbjct: 15  IKGELSGDYKELVMAL---FVAPAEYDAWCIKEAIYGPGTDEMALMEILMTRTNAQIKEL 185

Query: 290 REIFRTKYEKSLYSM-------IKNDTSGEYKKALLKLCGG 323
           R I+ +      +         I++D SG++K+ L+    G
Sbjct: 186 RSIYPSVLNDHYHGRTPKIEQDIEDDCSGDFKRLLISASQG 308

 Score = 44.3 bits (103), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 23/70 (32%), Positives = 43/70 (61%), Gaps = 7/70 (10%)
 Frame = +3

Query: 368 DAKALRKAMKGIGTDEATIIDIVTHRSNAQRQQIRQTFKS-----HFGR--DLMADLKSE 420
           DA  +++A+ G GTDE  +++I+  R+NAQ +++R  + S     + GR   +  D++ +
Sbjct: 84  DAWCIKEAIYGPGTDEMALMEILMTRTNAQIKELRSIYPSVLNDHYHGRTPKIEQDIEDD 263

Query: 421 ISGDLARLIL 430
            SGD  RL++
Sbjct: 264 CSGDFKRLLI 293
>17882
          Length = 489

 Score = 60.1 bits (144), Expect(2) = 9e-16,   Method: Compositional matrix adjust.
 Identities = 27/55 (49%), Positives = 40/55 (72%)
 Frame = -1

Query: 616 GTDEKTLTRVMVSRSEIDLLNIRREFIEKYDKSLHQAIEGDTSGDFMKALLALCG 670
           GT++  L R++VSRSEIDL +I+  ++ KY K+L  A+  DTSGD+ + LLA+ G
Sbjct: 351 GTNDSRLIRIIVSRSEIDLQDIKDVYLSKYKKTLESAVASDTSGDYKRLLLAIVG 187

 Score = 42.0 bits (97), Expect(2) = 9e-16,   Method: Compositional matrix adjust.
 Identities = 19/41 (46%), Positives = 27/41 (65%)
 Frame = -2

Query: 573 DIEHVIKKEMSGDVKDAFVAIVQSVKNKPLFFADKLYKSMK 613
           D+   I  EMSGD +    AIV+ +KN+P +FADKL+  +K
Sbjct: 479 DLLSSISSEMSGDFETGLRAIVRCMKNRPEYFADKLHDCIK 357

 Score = 67.0 bits (162), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 30/56 (53%), Positives = 46/56 (82%)
 Frame = -1

Query: 267 LGTRDNTLIRIMVSRSELDMLDIREIFRTKYEKSLYSMIKNDTSGEYKKALLKLCG 322
           LGT D+ LIRI+VSRSE+D+ DI++++ +KY+K+L S + +DTSG+YK+ LL + G
Sbjct: 354 LGTNDSRLIRIIVSRSEIDLQDIKDVYLSKYKKTLESAVASDTSGDYKRLLLAIVG 187

 Score = 50.4 bits (119), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 29/73 (39%), Positives = 41/73 (56%)
 Frame = -2

Query: 223 GKPIEASIRGELSGDFEKLMLAVVKCIRSTPEYFAERLFKAMKGLGTRDNTLIRIMVSRS 282
           GK + +SI  E+SGDFE  + A+V+C+++ PEYFA++L   +K L              S
Sbjct: 485 GKDLLSSISSEMSGDFETGLRAIVRCMKNRPEYFADKLHDCIKFLAPTTPV-------*S 327

Query: 283 ELDMLDIREIFRT 295
           EL   D R  FRT
Sbjct: 326 ELSCPDQRLTFRT 288

 Score = 39.3 bits (90), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 17/55 (30%), Positives = 34/55 (61%)
 Frame = -1

Query: 108 VGTDEKCLIEILASRTNEQMHQLVAAYKDAYERDLESDIIGDTSGHFQKMLVVLL 162
           +GT++  LI I+ SR+   +  +   Y   Y++ LES +  DTSG ++++L+ ++
Sbjct: 354 LGTNDSRLIRIIVSRSEIDLQDIKDVYLSKYKKTLESAVASDTSGDYKRLLLAIV 190
>13827
          Length = 483

 Score = 62.0 bits (149), Expect(2) = 2e-11,   Method: Compositional matrix adjust.
 Identities = 25/59 (42%), Positives = 45/59 (76%)
 Frame = -1

Query: 265 KGLGTRDNTLIRIMVSRSELDMLDIREIFRTKYEKSLYSMIKNDTSGEYKKALLKLCGG 323
           +G+GT D TLIR++V+R E+DM  I++ F+ +Y ++L + +++D SG+Y++ +L L GG
Sbjct: 444 RGMGTDDRTLIRVVVTRCEVDMKQIKQEFQNRYGQALEAFVRDDISGDYRRLMLALVGG 268

 Score = 25.0 bits (53), Expect(2) = 2e-11,   Method: Composition-based stats.
 Identities = 10/16 (62%), Positives = 13/16 (81%)
 Frame = -3

Query: 255 YFAERLFKAMKGLGTR 270
           YFA+RL+ +MKG G R
Sbjct: 475 YFADRLYHSMKGDGHR 428

 Score = 61.2 bits (147), Expect(2) = 3e-11,   Method: Compositional matrix adjust.
 Identities = 26/59 (44%), Positives = 42/59 (71%)
 Frame = -1

Query: 613 KGAGTDEKTLTRVMVSRSEIDLLNIRREFIEKYDKSLHQAIEGDTSGDFMKALLALCGG 671
           +G GTD++TL RV+V+R E+D+  I++EF  +Y ++L   +  D SGD+ + +LAL GG
Sbjct: 444 RGMGTDDRTLIRVVVTRCEVDMKQIKQEFQNRYGQALEAFVRDDISGDYRRLMLALVGG 268

 Score = 25.8 bits (55), Expect(2) = 3e-11,   Method: Compositional matrix adjust.
 Identities = 10/14 (71%), Positives = 12/14 (85%)
 Frame = -3

Query: 603 FFADKLYKSMKGAG 616
           +FAD+LY SMKG G
Sbjct: 475 YFADRLYHSMKGDG 434

 Score = 51.2 bits (121), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 20/58 (34%), Positives = 38/58 (65%)
 Frame = -1

Query: 450 GAGTDEKTLIEILATRTNAEIRAINEAYKEDYHKSLEDALSSDTSGHFRRILISLATG 507
           G GTD++TLI ++ TR   +++ I + ++  Y ++LE  +  D SG +RR++++L  G
Sbjct: 441 GMGTDDRTLIRVVVTRCEVDMKQIKQEFQNRYGQALEAFVRDDISGDYRRLMLALVGG 268

 Score = 50.4 bits (119), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 23/57 (40%), Positives = 39/57 (68%)
 Frame = -1

Query: 377 KGIGTDEATIIDIVTHRSNAQRQQIRQTFKSHFGRDLMADLKSEISGDLARLILGLM 433
           +G+GTD+ T+I +V  R     +QI+Q F++ +G+ L A ++ +ISGD  RL+L L+
Sbjct: 444 RGMGTDDRTLIRVVVTRCEVDMKQIKQEFQNRYGQALEAFVRDDISGDYRRLMLALV 274

 Score = 41.2 bits (95), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 19/57 (33%), Positives = 35/57 (61%)
 Frame = -1

Query: 193 GTDEAQFIYILGNRSKQHLRLVFDEYLKTTGKPIEASIRGELSGDFEKLMLAVVKCI 249
           GTD+   I ++  R +  ++ +  E+    G+ +EA +R ++SGD+ +LMLA+V  I
Sbjct: 435 GTDDRTLIRVVVTRCEVDMKQIKQEFQNRYGQALEAFVRDDISGDYRRLMLALVGGI 265

 Score = 41.2 bits (95), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 17/58 (29%), Positives = 37/58 (63%)
 Frame = -1

Query: 107 GVGTDEKCLIEILASRTNEQMHQLVAAYKDAYERDLESDIIGDTSGHFQKMLVVLLQG 164
           G+GTD++ LI ++ +R    M Q+   +++ Y + LE+ +  D SG ++++++ L+ G
Sbjct: 441 GMGTDDRTLIRVVVTRCEVDMKQIKQEFQNRYGQALEAFVRDDISGDYRRLMLALVGG 268

 Score = 34.3 bits (77), Expect = 0.18,   Method: Compositional matrix adjust.
 Identities = 13/57 (22%), Positives = 36/57 (63%)
 Frame = -1

Query: 34  KGFGSDKESILELITSRSNKQRQEICQNYKSLYGKDLIEDLKYELTGKFERLIVNLM 90
           +G G+D  +++ ++ +R     ++I Q +++ YG+ L   ++ +++G + RL++ L+
Sbjct: 444 RGMGTDDRTLIRVVVTRCEVDMKQIKQEFQNRYGQALEAFVRDDISGDYRRLMLALV 274
>29756
          Length = 496

 Score = 55.1 bits (131), Expect = 9e-08,   Method: Compositional matrix adjust.
 Identities = 24/49 (48%), Positives = 35/49 (71%)
 Frame = +3

Query: 363 FNPDADAKALRKAMKGIGTDEATIIDIVTHRSNAQRQQIRQTFKSHFGR 411
           FN + D + LRKAMKG GTDE  IIDI+ +R++ QRQ ++  +K+ F +
Sbjct: 264 FNAEEDVQKLRKAMKGFGTDEKAIIDILGYRTSDQRQNLKLMYKNLFWK 410

 Score = 51.6 bits (122), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 21/52 (40%), Positives = 38/52 (73%)
 Frame = +3

Query: 17  FPEFDANQDAEALYTAMKGFGSDKESILELITSRSNKQRQEICQNYKSLYGK 68
           +P F+A +D + L  AMKGFG+D+++I++++  R++ QRQ +   YK+L+ K
Sbjct: 255 YPRFNAEEDVQKLRKAMKGFGTDEKAIIDILGYRTSDQRQNLKLMYKNLFWK 410

 Score = 40.8 bits (94), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 17/44 (38%), Positives = 29/44 (65%)
 Frame = +3

Query: 97  DAKEIKDAISGVGTDEKCLIEILASRTNEQMHQLVAAYKDAYER 140
           D ++++ A+ G GTDEK +I+IL  RT++Q   L   YK+ + +
Sbjct: 279 DVQKLRKAMKGFGTDEKAIIDILGYRTSDQRQNLKLMYKNLFWK 410

 Score = 40.4 bits (93), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 20/49 (40%), Positives = 31/49 (63%)
 Frame = +3

Query: 437 AHYDAKQLKKAMEGAGTDEKTLIEILATRTNAEIRAINEAYKEDYHKSL 485
           A  D ++L+KAM+G GTDEK +I+IL  RT+ + + +   YK  + K  
Sbjct: 270 AEEDVQKLRKAMKGFGTDEKAIIDILGYRTSDQRQNLKLMYKNLFWKRF 416
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|126506304|ref|NP_083909.2| CLIP-associating protein
CLASP2 isoform a [Mus musculus]
         (1286 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

25317                                                                 245   4e-66
13482                                                                 172   8e-43
27421                                                                  44   3e-04
21242                                                                  31   2.6  
09226                                                                  30   4.6  
>25317
          Length = 1017

 Score =  245 bits (626), Expect(2) = 4e-66,   Method: Compositional matrix adjust.
 Identities = 112/231 (48%), Positives = 163/231 (70%)
 Frame = +2

Query: 81  TDVPSVQIYSSRELEETLNKIREILSDDKHDWDQRANALKKIRSLLVAGAAQYDCFFQHL 140
           + +  +Q++SSR++ + ++K+   LSD   DW++R +  K  R+L++ GA  +D F Q L
Sbjct: 50  SSIALLQLFSSRDMMDQMSKVNAALSDANLDWEKRVDNFKIFRALVMNGATDHDEFHQQL 229

Query: 141 RLLDGALKLSAKDLRSQVVREACITVAHLSTVLGNKFDHGAEAIVPTLFNLVPNSAKVMA 200
           R ++ A     KDLRSQVVREAC+T+A+++  LG+K D  AE + P LFNL+PNSAK+MA
Sbjct: 230 RGMEPAFVSGVKDLRSQVVREACVTIAYMAQQLGSKLDRFAEVVFPALFNLIPNSAKIMA 409

Query: 201 TSGCAAIRFIIRHTHVPRLIPLITSNCTSKSVPVRRRSFEFLDLLLQEWQTHSLERHAAV 260
           TSGC  IRFII++ H  RLIP++T N ++KS  +RR+S EFL+ LL  W TH+LE+H A+
Sbjct: 410 TSGCVCIRFIIQYVHTNRLIPILTGNMSTKSNVIRRQSCEFLNQLLHSWGTHTLEKHIAL 589

Query: 261 LVETIKKGIHDADAEARVEARKTYMGLRNHFPGEAETLYNSLEPSYQKSLQ 311
           L ++I++GI DAD+EAR  +RK + G   HF  +A+ L  SL+PS QK LQ
Sbjct: 590 LQDSIRRGISDADSEARAFSRKAFWGFAEHFKSQADALLASLDPSKQKLLQ 742

 Score = 26.2 bits (56), Expect(2) = 4e-66,   Method: Composition-based stats.
 Identities = 11/18 (61%), Positives = 14/18 (77%)
 Frame = +1

Query: 70 AVDEDDFIKAFTDVPSVQ 87
          A DE+ FIK+F DVP V+
Sbjct: 1  AADEELFIKSFEDVPKVK 54
>13482
          Length = 530

 Score =  172 bits (436), Expect = 8e-43,   Method: Compositional matrix adjust.
 Identities = 79/156 (50%), Positives = 110/156 (70%)
 Frame = +2

Query: 66  GGAGAVDEDDFIKAFTDVPSVQIYSSRELEETLNKIREILSDDKHDWDQRANALKKIRSL 125
           G AGA DE+ FIK+F DVP V+++SSR++ + ++K+   LSD   DW++R +  K  R+L
Sbjct: 62  GEAGAADEELFIKSFEDVPKVKLFSSRDMMDQMSKVNAALSDANLDWEKRVDNFKIFRAL 241

Query: 126 LVAGAAQYDCFFQHLRLLDGALKLSAKDLRSQVVREACITVAHLSTVLGNKFDHGAEAIV 185
           ++ GA  +D F Q LR ++ A     KDLRSQVVREAC+T+A+++  LG+K D  AE + 
Sbjct: 242 VMNGATDHDEFHQQLRGMEPAFVSGVKDLRSQVVREACVTIAYMAQQLGSKLDRFAEVVF 421

Query: 186 PTLFNLVPNSAKVMATSGCAAIRFIIRHTHVPRLIP 221
           P LFNL+PNSAK+MATSGC  IRFII++ H  R  P
Sbjct: 422 PALFNLIPNSAKIMATSGCVCIRFIIQYVHTNRQTP 529
>27421
          Length = 374

 Score = 44.3 bits (103), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 37/115 (32%), Positives = 52/115 (45%)
 Frame = -3

Query: 496 AQKRSKIPRSQGCSREASPSRLSVARSSRIPRPSVSQGCSREASRESSRDTSPVRSFQPL 555
            ++++ IPRSQG SREASP+R +  R  R+   S S+G            T P+      
Sbjct: 264 GKRKTGIPRSQGASREASPNRRTYGRERRL---SGSKGS----------HTGPL------ 142

Query: 556 GPGYGIXXXXXXXXXXXAMRVLNTGSDVEEAVADALLLGDIRTKKKPARRRYESY 610
                            + RVL  GSDVE+A+ DAL         +P R+RY+ Y
Sbjct: 141 ----------------ISQRVLRPGSDVEDALHDAL--------SRPNRKRYDVY 49
>21242
          Length = 568

 Score = 31.2 bits (69), Expect = 2.6,   Method: Compositional matrix adjust.
 Identities = 17/46 (36%), Positives = 26/46 (56%)
 Frame = +1

Query: 1050 DLVAELLKELSNHNERIEERKIALYELMKLTQEESFSVWDEHFKTI 1095
            DL  +  + L N+NE  EERK A +E +K+  E+S    DE  + +
Sbjct: 433  DLWQQFRQALQNYNETTEERKTA-FEALKVKDEKSAKEIDEQMRKL 567
>09226
          Length = 920

 Score = 30.4 bits (67), Expect = 4.6,   Method: Compositional matrix adjust.
 Identities = 14/22 (63%), Positives = 15/22 (68%)
 Frame = -1

Query: 874 TGNGTQSSMGSPLTRPTPRSPA 895
           TGNGTQS   SP T P P +PA
Sbjct: 590 TGNGTQSPWWSPPTSPVPEAPA 525
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|21617847|ref|NP_598440.1| crystallin, zeta (quinone
reductase)-like 1 [Mus musculus]
         (348 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

18797                                                                 233   5e-66
17976                                                                  28   4.1  
19693                                                                  28   5.9  
>18797
          Length = 1159

 Score =  233 bits (594), Expect(2) = 5e-66,   Method: Compositional matrix adjust.
 Identities = 120/281 (42%), Positives = 179/281 (63%), Gaps = 5/281 (1%)
 Frame = -1

Query: 58  DFFPVGREVSGIVLEVGRKVTFFQPDDEVVGILPLDSEDPGLCEVIRVHEHYLVHKPEKV 117
           D  PVGR+VSGIV +VG +V+  +  DEVVGILPLD+   G  E     E  +  KP +V
Sbjct: 964 DRLPVGRDVSGIVKDVGSRVSTVKEGDEVVGILPLDTTTSGCGEFCIFREFDVAKKPHRV 785

Query: 118 SWTEAAGVIRDGVRACTALYYLSQLSPGKSVLIMDGASAFGTIAIQLAHHRGAKVISTAH 177
           S  EAA VI D VRA TAL+Y + +  G SVLIMDGA+  G++A+Q+A   GAKV++T  
Sbjct: 784 SHEEAAAVIGDAVRAYTALHYHTHVCAGDSVLIMDGATHAGSVAVQMALLWGAKVMTTYS 605

Query: 178 SLEDKQHLERLRPSIARVIDVSNGKVHVAESCLEETGGLGVDIVIDAGVRLYSKDDEPAV 237
           S+ +KQ L+   P++A+ ++++     +  + +EETGG+GVD ++D GVR++S +++ ++
Sbjct: 604 SVPEKQFLDSFHPTVAQTMELNQRSTLLVSTVMEETGGIGVDCIVDNGVRMFSNEEDVSL 425

Query: 238 -----KLHLPHKHDIITLLGVGGHWVTTEENLQLDPPDSHCLFLKGATVAFLNDEVWNLS 292
                K   PHK D+++ LG  G WVT++ +LQLDPPDS  LFL+ A+V FL    W L 
Sbjct: 424 MGEKTKFPKPHKQDVLSCLGFSGKWVTSQPDLQLDPPDSQQLFLRNASVHFLFPPSWTLM 245

Query: 293 NAQQGKYLCILKDVMEKLSAGVFRPLLDEPIPLYEAKVSME 333
            AQ G+Y   L D++EKL  GV +  + + +   E   +++
Sbjct: 244 RAQHGRYQHTLVDILEKLDKGVLKCKIAQIVTFEEVTSTLQ 122

 Score = 36.2 bits (82), Expect(2) = 5e-66,   Method: Compositional matrix adjust.
 Identities = 18/39 (46%), Positives = 25/39 (64%), Gaps = 1/39 (2%)
 Frame = -3

Query: 6    FQQSSTNEEVTFVFQEKE-NVPVTEDNFVRVQVKACALS 43
            +QQ  T EE T +F   E ++P  +DN + VQVKAC L+
Sbjct: 1133 YQQKQTTEERTSIFTAVEVDIPSLKDNEILVQVKACGLT 1017
>17976
          Length = 781

 Score = 28.5 bits (62), Expect = 4.1,   Method: Compositional matrix adjust.
 Identities = 24/85 (28%), Positives = 36/85 (42%), Gaps = 6/85 (7%)
 Frame = +3

Query: 167 HRGAKVISTAHSLEDKQHLERLR----PSIARVIDVSNGKVHVAESCLEETGGL--GVDI 220
           H G   ++  H    +Q  ER R    P   R      G+      CL+  GG+  G   
Sbjct: 510 HTGRTEMAGRHHAGRRQEEERGRQXAXPQGRRG*QKREGEP-ARRGCLQPAGGV*GGARE 686

Query: 221 VIDAGVRLYSKDDEPAVKLHLPHKH 245
           V  +G +++S    PA+  H PH+H
Sbjct: 687 VGCSGWKVWSTIYPPAILRHRPHQH 761
>19693
          Length = 526

 Score = 28.1 bits (61), Expect = 5.9,   Method: Compositional matrix adjust.
 Identities = 13/43 (30%), Positives = 23/43 (53%)
 Frame = +3

Query: 272 HCLFLKGATVAFLNDEVWNLSNAQQGKYLCILKDVMEKLSAGV 314
            CLF     + F N  +W +S  +QG+ LCIL ++  ++   +
Sbjct: 192 FCLF-YFCLIYFTNPNIWLISVDKQGRKLCILSELSAQICMYI 317
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|160333829|ref|NP_061363.2| sorting nexin 12 isoform 3
[Mus musculus]
         (166 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

01954                                                                 245   7e-66
12345                                                                  40   5e-04
01196                                                                  30   0.46 
07014                                                                  29   0.78 
10336                                                                  28   1.8  
30052                                                                  28   2.3  
16556                                                                  26   5.9  
>01954
          Length = 1966

 Score =  245 bits (625), Expect = 7e-66,   Method: Compositional matrix adjust.
 Identities = 124/160 (77%), Positives = 144/160 (90%)
 Frame = -3

Query: 1    MSDTAVADTRRLNSKPQDLTDAYGPPSNFLEIDIFNPQTVGVGRARFTTYEVRMRTNLPI 60
            M++TA A   R+NSK Q L DAY PP+NFLEIDI +PQT GV +AR+T YEVRM++NLP+
Sbjct: 1940 MANTATA---RINSKKQTLEDAYSPPANFLEIDIVDPQTHGVAKARYTDYEVRMKSNLPV 1770

Query: 61   FKLKESCVRRRYSDFEWLKNELERDSKIVVPPLPGKALKRQLPFRGDEGIFEESFIEERR 120
            FKL++S VRRRYSDFEWL++ELERDSKIVVPPLPGKALKRQLPFRGD+GIFEE FIEERR
Sbjct: 1769 FKLRDSSVRRRYSDFEWLRSELERDSKIVVPPLPGKALKRQLPFRGDDGIFEEEFIEERR 1590

Query: 121  QGLEQFINKIAGHPLAQNERCLHMFLQEEAIDRNYVPGKV 160
            +GLEQFINK+AGHPLAQNE+CLHMFLQE  ID+NYVPGK+
Sbjct: 1589 KGLEQFINKVAGHPLAQNEKCLHMFLQEPVIDKNYVPGKI 1470
>12345
          Length = 933

 Score = 40.0 bits (92), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 30/91 (32%), Positives = 47/91 (51%)
 Frame = +3

Query: 65  ESCVRRRYSDFEWLKNELERDSKIVVPPLPGKALKRQLPFRGDEGIFEESFIEERRQGLE 124
           ++ V RRY+DF  L        ++V+   P + L + LP +   G   E FIE+R++ L+
Sbjct: 285 KTTVLRRYNDFVAL-------YEMVMMRFPYRILPK-LPPKKMLGANRE-FIEQRKKSLK 437

Query: 125 QFINKIAGHPLAQNERCLHMFLQEEAIDRNY 155
           +FIN IA HP    ++ L  FL     D  +
Sbjct: 438 RFINIIARHPQINEDKLLKFFLTYSGNDMQH 530
>01196
          Length = 1546

 Score = 30.0 bits (66), Expect = 0.46,   Method: Compositional matrix adjust.
 Identities = 10/32 (31%), Positives = 19/32 (59%)
 Frame = -3

Query: 128 NKIAGHPLAQNERCLHMFLQEEAIDRNYVPGK 159
           + I GH ++ N+RCL ++  +    +N+ P K
Sbjct: 803 SSIXGHKVSFNKRCLTIYTDQAGXSQNFSPSK 708
>07014
          Length = 1664

 Score = 29.3 bits (64), Expect = 0.78,   Method: Compositional matrix adjust.
 Identities = 10/32 (31%), Positives = 19/32 (59%)
 Frame = -1

Query: 128 NKIAGHPLAQNERCLHMFLQEEAIDRNYVPGK 159
           + I GH ++ N+RCL ++  +    +N+ P K
Sbjct: 545 SSIXGHKVSFNKRCLTIYTDQAGQSQNFSPSK 450
>10336
          Length = 1279

 Score = 28.1 bits (61), Expect = 1.8,   Method: Compositional matrix adjust.
 Identities = 9/30 (30%), Positives = 18/30 (60%)
 Frame = -1

Query: 128 NKIAGHPLAQNERCLHMFLQEEAIDRNYVP 157
           + I GH ++ N+RCL ++  +    +N+ P
Sbjct: 943 SSIGGHKVSFNKRCLTIYTDQAGQSQNFSP 854
>30052
          Length = 430

 Score = 27.7 bits (60), Expect = 2.3,   Method: Compositional matrix adjust.
 Identities = 10/24 (41%), Positives = 17/24 (70%)
 Frame = -2

Query: 55  RTNLPIFKLKESCVRRRYSDFEWL 78
           +T + I K+KE C  RRYS+++ +
Sbjct: 222 KTTVMITKMKEKCKHRRYSEYKGI 151
>16556
          Length = 541

 Score = 26.2 bits (56), Expect = 5.9,   Method: Compositional matrix adjust.
 Identities = 11/20 (55%), Positives = 16/20 (80%)
 Frame = -3

Query: 54  MRTNLPIFKLKESCVRRRYS 73
           +R NLP+FKL  SC++R +S
Sbjct: 110 LRVNLPVFKL--SCIKRPFS 57
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|29789343|ref|NP_598677.1| eukaryotic translation
initiation factor 3, subunit 9 [Mus musculus]
         (803 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

00472                                                                 228   9e-66
11117                                                                 125   7e-29
06563                                                                  89   9e-18
28652                                                                  35   0.12 
02663                                                                  35   0.13 
03059                                                                  33   0.45 
21527                                                                  30   5.5  
08459                                                                  29   6.3  
>00472
          Length = 2194

 Score =  228 bits (582), Expect(2) = 9e-66,   Method: Compositional matrix adjust.
 Identities = 114/197 (57%), Positives = 140/197 (71%), Gaps = 10/197 (5%)
 Frame = +2

Query: 364  GVQLIDFSPCERYLVTFSPLMDTQDDPQAIIIWDILTGHKKRGFHCESSAHWPIFKWSHD 423
            GVQLIDFSPCERY    S L  T +     + + +     KRGFHC+    WPIFKWS D
Sbjct: 1610 GVQLIDFSPCERY**H-SAL*LTTERTLKPLSFGMFVLALKRGFHCKCQMTWPIFKWSPD 1786

Query: 424  GKFFARMTLDTLSIYETPSMGLLDKKSLKISGIKDFSWSPGGNIIAFWVPEDKDIPARVT 483
            G FFA M  D +S+YETPS GLLDKKS +I+ IKDFSWSP  +IIA+WVPE+ + PARVT
Sbjct: 1787 GSFFAXMRXDAISVYETPSFGLLDKKSXEITSIKDFSWSP-TDIIAYWVPEEXNTPARVT 1963

Query: 484  LMQLPTRQEIRVRNLFNVVDCKLHWQKNGDYLCVKVDRTPKGTQ----------GVVTNF 533
            L+++P+R E+ VRNLFNV DCK+HWQKNGD+LCVKVDR  K  +          G+  NF
Sbjct: 1964 LIEIPSRNELCVRNLFNVADCKMHWQKNGDHLCVKVDRYAKAKKVDEKEQVKYSGIYFNF 2143

Query: 534  EIFRMREKQVPVDVVEM 550
            E+FR+REKQ+PVD VE+
Sbjct: 2144 ELFRIREKQIPVDKVEI 2194

 Score = 41.2 bits (95), Expect(2) = 9e-66,   Method: Compositional matrix adjust.
 Identities = 18/24 (75%), Positives = 22/24 (91%)
 Frame = +3

Query: 338  LATFHQRGIALWGGDKFKQIQRFS 361
            +ATFHQ+GIALWGG+KF  +QRFS
Sbjct: 1539 VATFHQKGIALWGGEKF--VQRFS 1604
>11117
          Length = 573

 Score =  125 bits (314), Expect = 7e-29,   Method: Compositional matrix adjust.
 Identities = 60/123 (48%), Positives = 79/123 (64%)
 Frame = +2

Query: 660 SWWSHKVDNAYWLWTFQGRLLQKNNKDRFCQLLWRPRPPTXXXXXXXXXXXXXXXXXXXX 719
           SWW HKVDNAYW+W FQG LL K   +RFCQL+WRPR P+                    
Sbjct: 2   SWWGHKVDNAYWIWNFQGNLLVKQPMERFCQLMWRPRAPSLLTDKQIKEIKRNFKTWAQK 181

Query: 720 FEQKDRLSQSKASKELVERRRTMMEDFRQYRKMAQELYMKQKNERLELRGGVDTDELDSN 779
           FE +D + +  ASKE++E+R+ MME+F +     +E Y + K++RLELR GVDTDELDS+
Sbjct: 182 FETEDAMRKMTASKEMIEKRQNMMEEFSRLLAEKEERYKEMKSKRLELRXGVDTDELDSH 361

Query: 780 VDD 782
           VD+
Sbjct: 362 VDN 370
>06563
          Length = 2303

 Score = 88.6 bits (218), Expect = 9e-18,   Method: Compositional matrix adjust.
 Identities = 82/357 (22%), Positives = 143/357 (40%), Gaps = 17/357 (4%)
 Frame = -2

Query: 358  QRFSHQGVQLIDFSPCERYLVTFSPLM---DTQDDPQAIIIWDILTGHKKRGFHCESSAH 414
            Q+     V  + FSP    L T+ P     D +     ++IWD  +G+  + F  +    
Sbjct: 2107 QQLQQTRVAELMFSPRGSVLATWGPFYMDRDGKGGEPNMVIWDXASGNVLKTFVQKKQIG 1928

Query: 415  WPIFKWSHDGKFFARMTLDTLSIYETPSMGLLDKKSLKISGIKDFSWSPGGN--IIAFWV 472
            W +  WS D     R     +  YE  +   + ++ L +  + DFS +P     +I+ +V
Sbjct: 1927 WEL-AWSVDEAICCRTANSEVHFYENNNFDTVAQR-LHLQKVVDFSLAPASAPYVISAYV 1754

Query: 473  PEDKDIPARVTLMQLP----TRQEIRVRNLFNVVDCKLHWQKNGDYLCV-----KVDRTP 523
               K  P+ V + + P        I  ++ +        W K G  L +       D + 
Sbjct: 1753 AGVKGQPSFVRVYRYPHFDGQSAAIANKSFYKADRVNTFWNKTGTGLVILTSTESSDSSY 1574

Query: 524  KGTQGVVTNFEIFRMREKQVPVDVVEMKETIIAFAWEPNGSKFAVLHGEAPRISVSFYHV 583
             G QG+  ++         VP+   E K  + +  W P  ++F V++G  P     F   
Sbjct: 1573 YGEQGL--HYISTSGESCLVPL---EKKGPVYSVMWSPKNNEFCVVYGFMPAKVTLF--- 1418

Query: 584  KSNGKIELIKMFDKQQANTIFWSPQGQFVVLAGLRSMNGALAFVDTSDCTVMNIAEHYMA 643
              N K E +  F     N  F++PQG  + LAG  ++ G + F D      ++  +    
Sbjct: 1417 --NLKCEPVFDFGTGPRNHCFYNPQGNILCLAGFGNLAGHMEFWDLKQKKEISKFKAADT 1244

Query: 644  SDVEWDPTGRYVVTSVSWWSHKVDNAYWLWTFQGRLLQKNNK---DRFCQLLWRPRP 697
            ++  W P G + +T+      +V N Y LW + G LL   +    +     +W+P P
Sbjct: 1243 TNFAWSPDGEHFLTATVSPRLRVSNGYRLWHYTGSLLSSVSTPEGESLFDAIWQPAP 1073
>28652
          Length = 918

 Score = 35.0 bits (79), Expect = 0.12,   Method: Compositional matrix adjust.
 Identities = 14/37 (37%), Positives = 22/37 (59%)
 Frame = -2

Query: 218 TKGYIFLEYASPAHAVDAVKNADGYKLDKQHTFRVNL 254
            +GY F+ Y +   A +AVK  DGY++ K    +VN+
Sbjct: 611 NRGYCFVTYTTKEAAAEAVKQHDGYEIRKGKKLKVNI 501
>02663
          Length = 414

 Score = 35.0 bits (79), Expect = 0.13,   Method: Compositional matrix adjust.
 Identities = 16/22 (72%), Positives = 19/22 (86%)
 Frame = +1

Query: 142 FSDPEDFVDDVSEEELLGDVLK 163
           FSDP DFVD+ ++EELLGD LK
Sbjct: 346 FSDPPDFVDNPTDEELLGDFLK 411
>03059
          Length = 1154

 Score = 33.1 bits (74), Expect = 0.45,   Method: Compositional matrix adjust.
 Identities = 21/58 (36%), Positives = 32/58 (55%), Gaps = 3/58 (5%)
 Frame = -2

Query: 193 KNVIHKIFSKFGKIINDYYPEE---DGKTKGYIFLEYASPAHAVDAVKNADGYKLDKQ 247
           K+ I +IFS +G I     P +      +KG+ ++EY +P  A  AVK  DG ++D Q
Sbjct: 631 KDHIQEIFSLYGTIKFIDLPNDRIHPNTSKGHAYVEYENPEDAEKAVKYMDGGQIDGQ 458
>21527
          Length = 416

 Score = 29.6 bits (65), Expect = 5.5,   Method: Compositional matrix adjust.
 Identities = 15/53 (28%), Positives = 31/53 (58%)
 Frame = -3

Query: 190 EKLKNVIHKIFSKFGKIINDYYPEEDGKTKGYIFLEYASPAHAVDAVKNADGY 242
           ++LK  ++ IFS+FG+I+ D    +  K +G  F+ +     A +A+++  G+
Sbjct: 408 DELKKSLYAIFSQFGQIL-DIVAMKTLKMRGQAFVIFKEINSAANALRSMQGF 253
>08459
          Length = 1344

 Score = 29.3 bits (64), Expect = 6.3,   Method: Compositional matrix adjust.
 Identities = 23/106 (21%), Positives = 46/106 (43%), Gaps = 26/106 (24%)
 Frame = +1

Query: 188 RLEKLKNVIHKIFSKFGKI------------------------INDYYPEEDGKTKGYI- 222
           +L   ++++ K+F  FG++                        I  +Y  +D +   Y+ 
Sbjct: 829 KLRPSEDIVRKVFESFGEVRCVDIPMLDPYRKEIMGVLAKPGMIQTFYYGQDIQFDAYVQ 1008

Query: 223 FLEYASPAHAVDAVKNAD-GYKLDKQHTFRVNLFTDFDKYMTISDE 267
           F +Y S   A+DA++     +K D++  F   +  +FDK   +SD+
Sbjct: 1009FKDYISFVKAMDAMRGMKLMFKQDEEKAFTATIKVEFDKTRHLSDK 1146
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|118136297|ref|NP_035937.2| chapsyn-110 [Mus musculus]
         (852 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

08480                                                                 248   1e-65
29974                                                                 182   5e-46
13641                                                                 149   6e-36
29705                                                                 120   2e-27
33804                                                                  82   8e-21
27435                                                                  90   4e-18
35802                                                                  85   9e-17
11512                                                                  76   7e-14
20073                                                                  70   3e-12
29636                                                                  63   4e-10
27345                                                                  59   9e-09
03499                                                                  50   4e-06
26154                                                                  49   9e-06
03831                                                                  44   3e-04
39267                                                                  40   0.005
38751                                                                  40   0.006
02951                                                                  39   0.006
01502                                                                  39   0.007
37412                                                                  36   0.058
30740                                                                  34   0.21 
37239                                                                  33   0.37 
12324                                                                  33   0.40 
05562                                                                  32   1.3  
14282                                                                  30   3.1  
30747                                                                  29   6.3  
>08480
          Length = 698

 Score =  248 bits (632), Expect = 1e-65,   Method: Compositional matrix adjust.
 Identities = 134/237 (56%), Positives = 160/237 (67%), Gaps = 28/237 (11%)
 Frame = -1

Query: 453 GPADLSGELQRGDQILSVNGIDLRGASHEQAAAALKGAGQTVTIIAQYQPEDYARFEAKI 512
           GPADLSG+L+RGD+ILSVN +D+  A+HEQAA ALK AG TV IIAQY+PEDY RFEAKI
Sbjct: 698 GPADLSGDLRRGDKILSVNDVDVERATHEQAAQALKRAGDTVEIIAQYKPEDYNRFEAKI 519

Query: 513 HDLREQMMNHXXXXXXXXLRTNQKRSLYVRAMFDYDKSKDSGLPSQGLSFKYGDILHVIN 572
            DLREQMMN+        LRT QKR+++VRA+FDY+ SKDSGLPS+GL F YGDILHV N
Sbjct: 518 QDLREQMMNNSAGS----LRTTQKRTMFVRALFDYEPSKDSGLPSRGLWFHYGDILHVTN 351

Query: 573 ASDDEWWQARRVTLDGDSEEMGVIPSKRRVERKERARLKTVKFNA--------------- 617
           ASDDEWWQA+R+  DG  E MG+IPSKRRVERKERARL+ VKF                 
Sbjct: 350 ASDDEWWQAKRILPDGKEEGMGIIPSKRRVERKERARLRNVKFGKNSTSTDKPVKDKGKK 171

Query: 618 -------------KPGVIDSKGDIPGLGDDGYGTKTLRGQEDLILSYEPVTRQEINY 661
                        + G  D  GD    G+    + + RG+E  +LSYE VT+QE+ Y
Sbjct: 170 KSGRMFPFKKGKDQSGSEDVSGDEVEEGNLPSDSDSNRGEE-PVLSYETVTQQELKY 3

 Score = 41.2 bits (95), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 21/44 (47%), Positives = 26/44 (59%)
 Frame = -1

Query: 136 GAAAEDGRLRVNDCILRVNEVDVSEVSHSKAVEALKEAGSIVRL 179
           G A   G LR  D IL VN+VDV   +H +A +ALK AG  V +
Sbjct: 698 GPADLSGDLRRGDKILSVNDVDVERATHEQAAQALKRAGDTVEI 567

 Score = 37.7 bits (86), Expect = 0.018,   Method: Compositional matrix adjust.
 Identities = 18/44 (40%), Positives = 25/44 (56%)
 Frame = -1

Query: 231 GAAQKDGRLQVGDRLLMVNNYSLEEVTHEEAVAILKNTSDVVYL 274
           G A   G L+ GD++L VN+  +E  THE+A   LK   D V +
Sbjct: 698 GPADLSGDLRRGDKILSVNDVDVERATHEQAAQALKRAGDTVEI 567
>29974
          Length = 344

 Score =  182 bits (462), Expect = 5e-46,   Method: Compositional matrix adjust.
 Identities = 87/108 (80%), Positives = 94/108 (87%)
 Frame = +1

Query: 676 NDDLISEFPDKFGSCVPHTTRPKRDYEVDGRDYHFVISREQMEKDIQEHKFIEAGQYNDN 735
           NDDLISEFPDKFGSC+PHTTR +R  E  G+DYHFV SREQME+DIQ H FIEAG YNDN
Sbjct: 1   NDDLISEFPDKFGSCIPHTTRERRTNEEPGQDYHFVSSREQMERDIQNHLFIEAGVYNDN 180

Query: 736 LYGTSVQSVRFVAERGKHCILDVSGNAIKRLQVAQLYPIAIFIKPKSL 783
           LYGTSV SV+ VAE+G+HCILDVSGNAIKRLQVA LYPIAIFIKP  L
Sbjct: 181 LYGTSVASVKEVAEQGRHCILDVSGNAIKRLQVAGLYPIAIFIKPSRL 324
>13641
          Length = 2081

 Score =  149 bits (375), Expect = 6e-36,   Method: Compositional matrix adjust.
 Identities = 110/338 (32%), Positives = 174/338 (51%), Gaps = 36/338 (10%)
 Frame = +2

Query: 534 NQKRSLYVRAMFDYDKSKDSGLPSQ--GLSFKYGDILHVINASDDEWWQARRVTLDGDSE 591
           ++KR + V+AMF ++   D  +P +  GLSF+ GDILH++N  D  WWQA +    GD++
Sbjct: 137 SKKREMVVKAMFSFNSKLDDNIPCKEAGLSFQQGDILHIVNQEDAIWWQAYK---HGDAK 307

Query: 592 E-MGVIPSKRRVERKERARLKTVKFNAKPG-----VIDSKGDIPGLGDDGYGTKTLRG-- 643
           +  G+IPS+   ER+E  R    K  +K G      I      P +       KT+    
Sbjct: 308 KRAGLIPSRHYHERQEVLR----KSKSKEGRHMARSISPCRYSPKVPKQRRLRKTMYHIV 475

Query: 644 --------QEDLILSYEPVTR--QEINYTRPVIILGPM---KDRINDDLISEFPDKFGSC 690
                     D I +Y+ V     +  + RP++++G     ++ +   L +  P  F   
Sbjct: 476 QNGALTDFDTDEIPAYDEVEHFTPKPRHFRPIVLIGAPGIGRNELKRRLKASNPMHFLEV 655

Query: 691 VPHTTRPKRDYEVDGRDYHFVISREQMEKDIQEHKFIEAGQYNDNLYGTSVQSVRFVAER 750
           VP+TTR K+ +E DG++YHFV SRE ME+ I   KF+E G+++ +LYGTSV+S++ V   
Sbjct: 656 VPYTTRTKKPFEEDGKEYHFV-SREDMEESIIAQKFVEYGEHHGHLYGTSVESIKQVIAA 832

Query: 751 GKHCILDVSGNAIKRLQVAQLYPIAIFIKPKSLEPL----MEMNKRLTE---------EQ 797
           GK C+L     A+K L+  +L P  IFIK  +LE L    M    R TE         E+
Sbjct: 833 GKVCLLTPHTQALKFLRTYELKPYVIFIKSPTLEKLKESRMPARARATEADSIRPFSIEE 1012

Query: 798 AKKTYDRAIKLEQEFGEYFTAIVQGDTLEDIYNQCKLV 835
            ++  + + +LE+ +G  F   +  D+L D   +  +V
Sbjct: 1013LEEMAETSRRLEERYGHVFDITIVNDSLTDATTELLMV 1126
>29705
          Length = 674

 Score =  120 bits (302), Expect = 2e-27,   Method: Compositional matrix adjust.
 Identities = 75/184 (40%), Positives = 101/184 (54%), Gaps = 19/184 (10%)
 Frame = -1

Query: 118 NPHIGDDPGIFITKIIPGGAAAEDGRLRVNDCILRVNEVDVSEVSHSKAVEALKEAGSIV 177
           NPHIGDDP I+ITK+IP G            C  R    + +E  H ++    +     V
Sbjct: 674 NPHIGDDPSIYITKLIPRG------------CCCRGWPSE-TERHHCQSGH*RR-----V 549

Query: 178 RLYVRRRRPILETVVEIKLFKGP-------------------KGLGFSIAGGVGNQHIPG 218
           + +  RRR   +T+ +  L                       +G G     G GNQHIPG
Sbjct: 548 QHHSHRRR*CPQTLRQQSLLASETAEDSDRKSHRHRPGQGS*QGSGIQHCRGKGNQHIPG 369

Query: 219 DNSIYVTKIIDGGAAQKDGRLQVGDRLLMVNNYSLEEVTHEEAVAILKNTSDVVYLKVGK 278
           DN I++TK+I+GG+A++DGR+ V DRLL VN ++LE+VTHEEAVA LK+T DVV L + K
Sbjct: 368 DNGIFITKVIEGGSAEQDGRIAVMDRLLAVNEHNLEDVTHEEAVAALKSTGDVVRLTIAK 189

Query: 279 PTTI 282
           PT I
Sbjct: 188 PTYI 177

 Score = 72.8 bits (177), Expect = 5e-13,   Method: Compositional matrix adjust.
 Identities = 37/77 (48%), Positives = 50/77 (64%)
 Frame = -1

Query: 107 GLGFSIAGGTDNPHIGDDPGIFITKIIPGGAAAEDGRLRVNDCILRVNEVDVSEVSHSKA 166
           G G     G  N HI  D GIFITK+I GG+A +DGR+ V D +L VNE ++ +V+H +A
Sbjct: 419 GSGIQHCRGKGNQHIPGDNGIFITKVIEGGSAEQDGRIAVMDRLLAVNEHNLEDVTHEEA 240

Query: 167 VEALKEAGSIVRLYVRR 183
           V ALK  G +VRL + +
Sbjct: 239 VAALKSTGDVVRLTIAK 189

 Score = 45.1 bits (105), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 21/54 (38%), Positives = 34/54 (62%)
 Frame = -1

Query: 443 GIFVSFILAGGPADLSGELQRGDQILSVNGIDLRGASHEQAAAALKGAGQTVTI 496
           GIF++ ++ GG A+  G +   D++L+VN  +L   +HE+A AALK  G  V +
Sbjct: 362 GIFITKVIEGGSAEQDGRIAVMDRLLAVNEHNLEDVTHEEAVAALKSTGDVVRL 201
>33804
          Length = 621

 Score = 81.6 bits (200), Expect(2) = 8e-21,   Method: Compositional matrix adjust.
 Identities = 35/54 (64%), Positives = 46/54 (85%)
 Frame = -1

Query: 799 KKTYDRAIKLEQEFGEYFTAIVQGDTLEDIYNQCKLVIEEQSGPFIWIPSKEKL 852
           +K ++RAIK+EQEFGEYFT +VQGDT+E+IY++ K +I  QSGP IW+PSKE L
Sbjct: 564 RKHFERAIKMEQEFGEYFTGVVQGDTIEEIYSKVKSMIWSQSGPNIWVPSKESL 403

 Score = 37.7 bits (86), Expect(2) = 8e-21,   Method: Composition-based stats.
 Identities = 15/22 (68%), Positives = 21/22 (95%)
 Frame = -3

Query: 781 KSLEPLMEMNKRLTEEQAKKTY 802
           KS++ +MEMN+R+TEEQAKKT+
Sbjct: 619 KSVDSVMEMNRRMTEEQAKKTF 554
>27435
          Length = 456

 Score = 89.7 bits (221), Expect = 4e-18,   Method: Compositional matrix adjust.
 Identities = 50/151 (33%), Positives = 85/151 (56%), Gaps = 5/151 (3%)
 Frame = +1

Query: 702 EVDGRDYHFVISREQMEKDIQEHKFIEAGQYNDNLYGTSVQSVRFVAERGKHCILDVSGN 761
           E +G+DYHF I+R   E D+   KF+E G++  NLYGT+V++VR V ++G+ CIL++   
Sbjct: 1   EHNGKDYHF-ITRAVFEADMLSGKFVEYGEFQGNLYGTTVEAVRQVIQQGRICILNLGPE 177

Query: 762 AIKRLQVAQLYPIAIFIKPKSLEPLMEMNKRL-----TEEQAKKTYDRAIKLEQEFGEYF 816
           ++K L+  +L P  IFI P  +E L ++   L     T++Q K+  +R  ++E+ +  YF
Sbjct: 178 SLKNLRETELKPYIIFISPPXMEKLRQLQMALGKPRPTDDQVKEVIERGREMEEMYSHYF 357

Query: 817 TAIVQGDTLEDIYNQCKLVIEEQSGPFIWIP 847
             I+    L   +++    I        W+P
Sbjct: 358 DYILVNMELNRAFDELLQEINRIETEPQWVP 450
>35802
          Length = 571

 Score = 85.1 bits (209), Expect = 9e-17,   Method: Compositional matrix adjust.
 Identities = 51/157 (32%), Positives = 90/157 (57%), Gaps = 10/157 (6%)
 Frame = +1

Query: 702 EVDGRDYHFVISREQMEKDIQEHKFIEAGQYNDNLYGTSVQSVRFVAERGKHCILDVSGN 761
           E+ GRDYHF  SR   E D+   KF+E G++  NLYGTSV++VR V  +G+ C+L++   
Sbjct: 1   EMTGRDYHFT-SRSMFEADMLSGKFLEYGEFQSNLYGTSVEAVRQVILQGRVCLLNLEPE 177

Query: 762 AIKRLQVAQLYPIAIFIKPKSLEPLMEMN-----KRLTEEQAKKTYDRAIKLEQEFGEYF 816
           ++K L+   L P   F+ P ++E L +++      R T++Q K   D+  ++E  +G +F
Sbjct: 178 SLKILRETDLKPYTXFVCPPNMEKLRQLHIAMGKIRPTDDQLKTVMDKGREMEDMYGHFF 357

Query: 817 T-AIVQGD---TLEDIYNQC-KLVIEEQSGPFIWIPS 848
              +V  D   +++++  +  ++ +E Q  P  W+ S
Sbjct: 358 DYKLVNMDVDRSVQELMAEINRIEVEPQWVPVTWMNS 468
>11512
          Length = 1006

 Score = 75.9 bits (185), Expect = 7e-14,   Method: Compositional matrix adjust.
 Identities = 51/158 (32%), Positives = 78/158 (49%), Gaps = 18/158 (11%)
 Frame = -3

Query: 709  HFVISREQMEKDIQEHKFIEAGQYNDNLYGTSVQSVRFVAERGKHCILDVSGNAIKRLQV 768
            +  ++RE+M+ DI+  KF+E G+Y  +LYGTS +SV+ +   G  C+L     AIK L+ 
Sbjct: 1004 YIFVAREKMDADIEAGKFVEHGEYKGHLYGTSAESVKSIVNAGCVCVLSPHYQAIKTLRT 825

Query: 769  AQLYPIAIFIKPKSLEPLMEMNKRLTEEQAKKTYDRA-----------------IKLEQE 811
             QL P  I IKP  L+ L       TE +AK T+D A                  +++  
Sbjct: 824  XQLKPFLIHIKPPELDILKSTR---TEARAKSTFDEANARSFTDEEFEDMIKSTXRIDFT 654

Query: 812  FGEYF-TAIVQGDTLEDIYNQCKLVIEEQSGPFIWIPS 848
            +G +F   IV G+ L       + V   ++ P +W PS
Sbjct: 653  YGHFFDVEIVNGELLAAFEXLVQHVQRLENEP-LWAPS 543
>20073
          Length = 582

 Score = 70.1 bits (170), Expect = 3e-12,   Method: Compositional matrix adjust.
 Identities = 37/85 (43%), Positives = 53/85 (62%), Gaps = 1/85 (1%)
 Frame = +3

Query: 430 GLGFNIVGG-EDGEGIFVSFILAGGPADLSGELQRGDQILSVNGIDLRGASHEQAAAALK 488
           GLGFN++GG E    I++S I+ GG AD    L+RGDQ+LSVNG+ + G  HE+A   LK
Sbjct: 3   GLGFNVMGGKEQSSPIYISRIIPGGVADRLNCLKRGDQLLSVNGVSVEGEYHEKAVELLK 182

Query: 489 GAGQTVTIIAQYQPEDYARFEAKIH 513
            A  +V ++ +Y P+     EA+  
Sbjct: 183 LAQGSVRLVVRYTPQILEEMEARFE 257

 Score = 55.5 bits (132), Expect = 8e-08,   Method: Compositional matrix adjust.
 Identities = 38/83 (45%), Positives = 46/83 (55%)
 Frame = +3

Query: 107 GLGFSIAGGTDNPHIGDDPGIFITKIIPGGAAAEDGRLRVNDCILRVNEVDVSEVSHSKA 166
           GLGF++ GG +       P I+I++IIPGG A     L+  D +L VN V V    H KA
Sbjct: 3   GLGFNVMGGKEQ----SSP-IYISRIIPGGVADRLNCLKRGDQLLSVNGVSVEGEYHEKA 167

Query: 167 VEALKEAGSIVRLYVRRRRPILE 189
           VE LK A   VRL VR    ILE
Sbjct: 168 VELLKLAQGSVRLVVRYTPQILE 236

 Score = 49.3 bits (116), Expect = 6e-06,   Method: Compositional matrix adjust.
 Identities = 33/75 (44%), Positives = 44/75 (58%)
 Frame = +3

Query: 202 GLGFSIAGGVGNQHIPGDNSIYVTKIIDGGAAQKDGRLQVGDRLLMVNNYSLEEVTHEEA 261
           GLGF++ GG   Q  P    IY+++II GG A +   L+ GD+LL VN  S+E   HE+A
Sbjct: 3   GLGFNVMGG-KEQSSP----IYISRIIPGGVADRLNCLKRGDQLLSVNGVSVEGEYHEKA 167

Query: 262 VAILKNTSDVVYLKV 276
           V +LK     V L V
Sbjct: 168 VELLKLAQGSVRLVV 212
>29636
          Length = 354

 Score = 63.2 bits (152), Expect = 4e-10,   Method: Compositional matrix adjust.
 Identities = 38/98 (38%), Positives = 54/98 (55%), Gaps = 4/98 (4%)
 Frame = +1

Query: 539 LYVRAMFDYDKSKDSGLPSQ--GLSFKYGDILHVINASDDEWWQARRVTLDGDSEEM--G 594
           +++RA+F+YD   D  +P +  G+SF  GDILH I  SD  WWQA R   +G+   M  G
Sbjct: 70  MHLRALFNYDPEDDPYIPCRELGISFLKGDILHAIQLSDSNWWQAHR---EGEDAHMLAG 240

Query: 595 VIPSKRRVERKERARLKTVKFNAKPGVIDSKGDIPGLG 632
           +IPSK   E++E  R    + NA+      +G I   G
Sbjct: 241 LIPSKAFQEQRESVR---QQLNAENKENKKRGRICACG 345
>27345
          Length = 496

 Score = 58.9 bits (141), Expect = 9e-09,   Method: Composition-based stats.
 Identities = 28/62 (45%), Positives = 41/62 (66%)
 Frame = +3

Query: 217 PGDNSIYVTKIIDGGAAQKDGRLQVGDRLLMVNNYSLEEVTHEEAVAILKNTSDVVYLKV 276
           PG   I++  + DGGAAQKDGR+QV D+++ V+  SL  VT   A ++L+NTS  V   +
Sbjct: 12  PGKLGIFIKTLTDGGAAQKDGRIQVNDQIIEVDGKSLVGVTQAYAASVLRNTSGQVTFHI 191

Query: 277 GK 278
           G+
Sbjct: 192 GR 197

 Score = 42.0 bits (97), Expect = 0.001,   Method: Composition-based stats.
 Identities = 21/60 (35%), Positives = 34/60 (56%)
 Frame = +3

Query: 126 GIFITKIIPGGAAAEDGRLRVNDCILRVNEVDVSEVSHSKAVEALKEAGSIVRLYVRRRR 185
           GIFI  +  GGAA +DGR++VND I+ V+   +  V+ + A   L+     V  ++ R +
Sbjct: 24  GIFIKTLTDGGAAQKDGRIQVNDQIIEVDGKSLVGVTQAYAASVLRNTSGQVTFHIGRDK 203

 Score = 38.9 bits (89), Expect = 0.009,   Method: Composition-based stats.
 Identities = 20/53 (37%), Positives = 28/53 (52%)
 Frame = +3

Query: 443 GIFVSFILAGGPADLSGELQRGDQILSVNGIDLRGASHEQAAAALKGAGQTVT 495
           GIF+  +  GG A   G +Q  DQI+ V+G  L G +   AA+ L+     VT
Sbjct: 24  GIFIKTLTDGGAAQKDGRIQVNDQIIEVDGKSLVGVTQAYAASVLRNTSGQVT 182
>03499
          Length = 1247

 Score = 50.1 bits (118), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 34/98 (34%), Positives = 53/98 (54%), Gaps = 4/98 (4%)
 Frame = -3

Query: 403  RQPSVTLQRAISLEGEPRKVVLHKGSTGLGFNIVGGE--DGEGIFVSFILAGGPADLSGE 460
            ++P  T Q    L+GE  K  L K   G GF IVG +  D E + +  ++  GPA L+G+
Sbjct: 1026 KKPFFTKQPG-ELQGEFVKTSLVKSVRGFGFTIVGSDHPDTEFLQIKNVVPNGPAYLNGK 850

Query: 461  LQRGDQILSVNGIDLRGASHEQAAAALK--GAGQTVTI 496
            L+ GD I+ VN   + G +H+   +  +    G+TVT+
Sbjct: 849  LKTGDVIVFVNTTCVLGYTHQDVVSLFQTISPGETVTL 736
>26154
          Length = 446

 Score = 48.9 bits (115), Expect = 9e-06,   Method: Compositional matrix adjust.
 Identities = 37/120 (30%), Positives = 61/120 (50%), Gaps = 6/120 (5%)
 Frame = -3

Query: 136 GAAAEDGRLRVNDCILRVNEVDVSEVSHSKAVEALKEAGSIVRLYVRRRRP------ILE 189
           G+A   G ++  D ++ +N+V +   +   A   L+    +V+L V+R  P       + 
Sbjct: 408 GSAHRCGSIQAGDKLMAINDVRLDTCTVDDATHLLELPDELVKLKVQRDDPDEGNEDCVT 229

Query: 190 TVVEIKLFKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIDGGAAQKDGRLQVGDRLLMVN 249
             V++    GP  LG +I+G       P DN I ++++  GG AQK G + VGDRLL +N
Sbjct: 228 YTVQLYRHGGP--LGITISG----TEDPLDN-IVISELTAGGLAQKTGAMHVGDRLLGIN 70

 Score = 36.2 bits (82), Expect = 0.058,   Method: Compositional matrix adjust.
 Identities = 26/89 (29%), Positives = 46/89 (51%), Gaps = 12/89 (13%)
 Frame = -3

Query: 231 GAAQKDGRLQVGDRLLMVNNYSLEEVTHEEAVAILKNTSDVVYLKV--------GKPTTI 282
           G+A + G +Q GD+L+ +N+  L+  T ++A  +L+   ++V LKV         +    
Sbjct: 408 GSAHRCGSIQAGDKLMAINDVRLDTCTVDDATHLLELPDELVKLKVQRDDPDEGNEDCVT 229

Query: 283 YMTDPY---GPPDITHSYSP-PMENHLLS 307
           Y    Y   GP  IT S +  P++N ++S
Sbjct: 228 YTVQLYRHGGPLGITISGTEDPLDNIVIS 142

 Score = 31.2 bits (69), Expect = 1.8,   Method: Compositional matrix adjust.
 Identities = 19/51 (37%), Positives = 29/51 (56%), Gaps = 1/51 (1%)
 Frame = -3

Query: 422 VVLHKGSTGLGFNIVGGEDG-EGIFVSFILAGGPADLSGELQRGDQILSVN 471
           V L++    LG  I G ED  + I +S + AGG A  +G +  GD++L +N
Sbjct: 222 VQLYRHGGPLGITISGTEDPLDNIVISELTAGGLAQKTGAMHVGDRLLGIN 70
>03831
          Length = 1143

 Score = 43.9 bits (102), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 25/83 (30%), Positives = 41/83 (49%)
 Frame = +3

Query: 429 TGLGFNIVGGEDGEGIFVSFILAGGPADLSGELQRGDQILSVNGIDLRGASHEQAAAALK 488
            G GFN+   +   G F+  +  G PA+ +G L+ GD+I+ VNG ++   +H+Q    +K
Sbjct: 165 NGYGFNLHAEKGKAGQFIGKVDEGSPAEAAG-LKAGDRIVEVNGTNIGNENHQQVVGRIK 341

Query: 489 GAGQTVTIIAQYQPEDYARFEAK 511
             G    ++   Q  D    E K
Sbjct: 342 AGGDETRLLVVDQETDQHYKEEK 410

 Score = 36.6 bits (83), Expect = 0.041,   Method: Compositional matrix adjust.
 Identities = 19/68 (27%), Positives = 35/68 (51%)
 Frame = +3

Query: 430 GLGFNIVGGEDGEGIFVSFILAGGPADLSGELQRGDQILSVNGIDLRGASHEQAAAALKG 489
           G GFN+   +D  G ++  +    PA+  G L+ GD+I+ VNG ++   +H      +K 
Sbjct: 615 GYGFNLHAEKDKPGQYIGSVDPNSPAETGG-LKEGDRIIEVNGENIETTNHTAVIQNIKS 791

Query: 490 AGQTVTII 497
            G   +++
Sbjct: 792 RGDKTSML 815
>39267
          Length = 456

 Score = 39.7 bits (91), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 22/68 (32%), Positives = 40/68 (58%)
 Frame = +1

Query: 202 GLGFSIAGGVGNQHIPGDNSIYVTKIIDGGAAQKDGRLQVGDRLLMVNNYSLEEVTHEEA 261
           GLGF+I+G +        + IYV+++ + G A + G++ VGDR+  V   + + + +E+A
Sbjct: 115 GLGFNISGNM-------RDGIYVSQLHNRGPASESGKIHVGDRIQSV-TIAYDNIVYEDA 270

Query: 262 VAILKNTS 269
           + IL   S
Sbjct: 271 LTILSYAS 294

 Score = 38.9 bits (89), Expect = 0.010,   Method: Compositional matrix adjust.
 Identities = 25/56 (44%), Positives = 31/56 (55%), Gaps = 1/56 (1%)
 Frame = +1

Query: 416 EGEPRKVVLHKGST-GLGFNIVGGEDGEGIFVSFILAGGPADLSGELQRGDQILSV 470
           E     V LH     GLGFNI G    +GI+VS +   GPA  SG++  GD+I SV
Sbjct: 70  EAATESVWLHSQDIIGLGFNISGNMR-DGIYVSQLHNRGPASESGKIHVGDRIQSV 234
>38751
          Length = 329

 Score = 39.7 bits (91), Expect = 0.006,   Method: Composition-based stats.
 Identities = 21/51 (41%), Positives = 31/51 (60%)
 Frame = +3

Query: 222 IYVTKIIDGGAAQKDGRLQVGDRLLMVNNYSLEEVTHEEAVAILKNTSDVV 272
           I V  I +G  A++ G L +GDR+L VN      +TH EAV I++N  +V+
Sbjct: 39  IVVYVIEEGCQAEQQG-LNIGDRILDVNGTDFTHLTHAEAVTIMRNAWNVI 188

 Score = 34.3 bits (77), Expect = 0.22,   Method: Composition-based stats.
 Identities = 25/67 (37%), Positives = 32/67 (47%)
 Frame = +3

Query: 437 GGEDGEGIFVSFILAGGPADLSGELQRGDQILSVNGIDLRGASHEQAAAALKGAGQTVTI 496
           G E G  I V  I  G  A+  G L  GD+IL VNG D    +H +A   ++ A   V +
Sbjct: 18  GKEYGTPIVVYVIEEGCQAEQQG-LNIGDRILDVNGTDFTHLTHAEAVTIMRNA-WNVIM 191

Query: 497 IAQYQPE 503
             Q  PE
Sbjct: 192 TVQPCPE 212
>02951
          Length = 1076

 Score = 39.3 bits (90), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 23/66 (34%), Positives = 39/66 (59%)
 Frame = +2

Query: 124 DPGIFITKIIPGGAAAEDGRLRVNDCILRVNEVDVSEVSHSKAVEALKEAGSIVRLYVRR 183
           D GI++T I     AA  G L+++D IL++N  D + V+H +AVE +++   +  L  R+
Sbjct: 14  DKGIYVTFIYENSPAARCG-LQLHDKILQLNGKDFTVVTHKQAVENIRKKPVLKMLVYRK 190

Query: 184 RRPILE 189
             P L+
Sbjct: 191 GVPQLQ 208

 Score = 38.1 bits (87), Expect = 0.013,   Method: Compositional matrix adjust.
 Identities = 20/51 (39%), Positives = 29/51 (56%)
 Frame = +2

Query: 438 GEDGEGIFVSFILAGGPADLSGELQRGDQILSVNGIDLRGASHEQAAAALK 488
           G   +GI+V+FI    PA   G LQ  D+IL +NG D    +H+QA   ++
Sbjct: 5   GYPDKGIYVTFIYENSPAARCG-LQLHDKILQLNGKDFTVVTHKQAVENIR 154
>01502
          Length = 1949

 Score = 39.3 bits (90), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 23/66 (34%), Positives = 39/66 (59%)
 Frame = +1

Query: 124 DPGIFITKIIPGGAAAEDGRLRVNDCILRVNEVDVSEVSHSKAVEALKEAGSIVRLYVRR 183
           D GI++T I     AA  G L+++D IL++N  D + V+H +AVE +++   +  L  R+
Sbjct: 28  DKGIYVTFIYENSPAARCG-LQLHDKILQLNGKDFTVVTHKQAVENIRKKPVLKMLVYRK 204

Query: 184 RRPILE 189
             P L+
Sbjct: 205 GVPQLQ 222

 Score = 38.9 bits (89), Expect = 0.010,   Method: Compositional matrix adjust.
 Identities = 19/47 (40%), Positives = 28/47 (59%)
 Frame = +1

Query: 442 EGIFVSFILAGGPADLSGELQRGDQILSVNGIDLRGASHEQAAAALK 488
           +GI+V+FI    PA   G LQ  D+IL +NG D    +H+QA   ++
Sbjct: 31  KGIYVTFIYENSPAARCG-LQLHDKILQLNGKDFTVVTHKQAVENIR 168
>37412
          Length = 757

 Score = 36.2 bits (82), Expect = 0.058,   Method: Composition-based stats.
 Identities = 16/39 (41%), Positives = 24/39 (61%)
 Frame = -3

Query: 751 GKHCILDVSGNAIKRLQVAQLYPIAIFIKPKSLEPLMEM 789
           GK C+LDV+  ++K L+ A+  P  +FI   S+E L  M
Sbjct: 629 GKMCVLDVNPTSLKVLKTAEFLPYIVFIAAPSVEALKVM 513
>30740
          Length = 488

 Score = 34.3 bits (77), Expect = 0.21,   Method: Compositional matrix adjust.
 Identities = 14/30 (46%), Positives = 19/30 (63%)
 Frame = +2

Query: 553 SGLPSQGLSFKYGDILHVINASDDEWWQAR 582
           SG   + L F  GDIL +I+  ++EWW AR
Sbjct: 212 SGRDPEDLPFSKGDILELISKDEEEWWTAR 301
>37239
          Length = 453

 Score = 33.5 bits (75), Expect = 0.37,   Method: Composition-based stats.
 Identities = 16/28 (57%), Positives = 19/28 (67%)
 Frame = -3

Query: 218 GDNSIYVTKIIDGGAAQKDGRLQVGDRL 245
           G + IY+  I  GGAA KDG+L VGD L
Sbjct: 85  GRHGIYIRHITIGGAAAKDGQLAVGDEL 2

 Score = 29.6 bits (65), Expect = 5.6,   Method: Composition-based stats.
 Identities = 14/23 (60%), Positives = 17/23 (73%)
 Frame = -3

Query: 126 GIFITKIIPGGAAAEDGRLRVND 148
           GI+I  I  GGAAA+DG+L V D
Sbjct: 76  GIYIRHITIGGAAAKDGQLAVGD 8
>12324
          Length = 946

 Score = 33.5 bits (75), Expect = 0.40,   Method: Compositional matrix adjust.
 Identities = 19/59 (32%), Positives = 31/59 (52%)
 Frame = +3

Query: 541 VRAMFDYDKSKDSGLPSQGLSFKYGDILHVINASDDEWWQARRVTLDGDSEEMGVIPSK 599
           V A++DY+  KD       L+F    +++VI  +DD WW+     +DG +   G+ PS 
Sbjct: 696 VVAIYDYEAEKD-----DELTFSENSVIYVIRKNDDGWWEG---VMDGVT---GLFPSN 839
>05562
          Length = 1116

 Score = 31.6 bits (70), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 24/88 (27%), Positives = 40/88 (45%), Gaps = 3/88 (3%)
 Frame = -2

Query: 710  FVISREQM---EKDIQEHKFIEAGQYNDNLYGTSVQSVRFVAERGKHCILDVSGNAIKRL 766
            F++ R Q     +DI   + +E G +   +YG    ++  V +RG  C+       I+ L
Sbjct: 1088 FMVFRPQAPWGRRDIALQQNVENG-HRKAVYGQLSSALHLVLDRGDPCL------TIQSL 930

Query: 767  QVAQLYPIAIFIKPKSLEPLMEMNKRLT 794
                L  +AI + P  L P+M M +R  
Sbjct: 929  GFLPLIKVAIIV-PGPLAPVMNMTERFV 849
>14282
          Length = 874

 Score = 30.4 bits (67), Expect = 3.1,   Method: Compositional matrix adjust.
 Identities = 11/22 (50%), Positives = 16/22 (72%)
 Frame = -2

Query: 10  RTNVKKYRYQDEDGPHDHSLPR 31
           RTN++KY + +   PH +SLPR
Sbjct: 342 RTNIRKYSFANRVAPHWNSLPR 277
>30747
          Length = 1168

 Score = 29.3 bits (64), Expect = 6.3,   Method: Compositional matrix adjust.
 Identities = 22/62 (35%), Positives = 33/62 (53%)
 Frame = +3

Query: 706 RDYHFVISREQMEKDIQEHKFIEAGQYNDNLYGTSVQSVRFVAERGKHCILDVSGNAIKR 765
           RD   V   E +E   QE  F +   Y  +L+GT + +V  + +  K  +LDVSGN I +
Sbjct: 135 RDVKIVSPAEILEL-CQEEDFYKV--YEVDLHGTEITAVPDLEKFRKLRVLDVSGNYITK 305

Query: 766 LQ 767
           +Q
Sbjct: 306 IQ 311
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|17157989|ref|NP_473384.1| Musashi homolog 2 [Mus
musculus]
         (346 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

11019                                                                 246   1e-65
19868                                                                 239   9e-64
01937                                                                 126   2e-38
03000                                                                 151   3e-37
03406                                                                 151   5e-37
26197                                                                  94   1e-29
16016                                                                 102   2e-27
32386                                                                 102   2e-22
12350                                                                  96   3e-20
31618                                                                  94   6e-20
00817                                                                  89   3e-18
33516                                                                  88   4e-18
02415                                                                  72   3e-13
23322                                                                  70   9e-13
11687                                                                  69   3e-12
24983                                                                  66   2e-11
17681                                                                  65   4e-11
16427                                                                  62   3e-10
10194                                                                  56   2e-08
02343                                                                  54   8e-08
23655                                                                  41   8e-08
05273                                                                  50   2e-06
09968                                                                  47   8e-06
00556                                                                  47   9e-06
17775                                                                  46   2e-05
00302                                                                  44   7e-05
02502                                                                  43   2e-04
13457                                                                  42   4e-04
08958                                                                  42   5e-04
31310                                                                  41   5e-04
28652                                                                  41   0.001
00029                                                                  40   0.001
39789                                                                  38   0.006
11126                                                                  38   0.006
25691                                                                  37   0.012
30672                                                                  35   0.051
35379                                                                  27   0.086
13822                                                                  33   0.16 
35180                                                                  32   0.41 
28455                                                                  31   0.68 
25950                                                                  31   0.75 
12096                                                                  31   0.91 
11108                                                                  30   0.96 
33504                                                                  30   1.2  
21869                                                                  30   1.9  
23250                                                                  29   2.5  
12506                                                                  28   4.2  
19556                                                                  28   4.9  
>11019
          Length = 552

 Score =  246 bits (627), Expect = 1e-65,   Method: Compositional matrix adjust.
 Identities = 115/184 (62%), Positives = 141/184 (76%), Gaps = 21/184 (11%)
 Frame = -1

Query: 25  IGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTFADPASVDKVLGQPHH 84
           IGGLSWQT+ ++LR YF KFGEI+E MVM+DPT+KRSRGFGFVT+ DP++VD VL    H
Sbjct: 552 IGGLSWQTTTETLRSYFEKFGEIKESMVMKDPTSKRSRGFGFVTYKDPSNVDNVLANGPH 373

Query: 85  ELDSKT---------------------IDPKVAFPRRAQPKMVTRTKKIFVGGLSANTVV 123
            +DSKT                     +DPKVAFPR++ P+MVT+TKKIFVGGLS++T V
Sbjct: 372 CIDSKTLNFSNMTTFYSNQDLLPYPPQVDPKVAFPRKSNPRMVTKTKKIFVGGLSSSTTV 193

Query: 124 EDVKQYFEQFGKVEDAMLMFDKTTNRHRGFGFVTFENEDVVEKVCEIHFHEINNKMVECK 183
           ED+K YF+ +G +E+A LMFDK T+RHRGF FVTF+NE  V+KVCEIHFHEIN+KMVE K
Sbjct: 192 EDIKNYFKAYGTIEEATLMFDKVTSRHRGFAFVTFDNESTVDKVCEIHFHEINSKMVETK 13

Query: 184 KAQP 187
           KAQP
Sbjct: 12  KAQP 1

 Score = 73.6 bits (179), Expect = 1e-13,   Method: Compositional matrix adjust.
 Identities = 34/77 (44%), Positives = 50/77 (64%)
 Frame = -1

Query: 22  KMFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTFADPASVDKVLGQ 81
           K+F+GGLS  T+ + +++YF  +G I E  +M D  T R RGF FVTF + ++VDKV   
Sbjct: 231 KIFVGGLSSSTTVEDIKNYFKAYGTIEEATLMFDKVTSRHRGFAFVTFDNESTVDKVCEI 52

Query: 82  PHHELDSKTIDPKVAFP 98
             HE++SK ++ K A P
Sbjct: 51  HFHEINSKMVETKKAQP 1
>19868
          Length = 434

 Score =  239 bits (611), Expect = 9e-64,   Method: Compositional matrix adjust.
 Identities = 113/140 (80%), Positives = 122/140 (87%)
 Frame = +2

Query: 22  KMFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTFADPASVDKVLGQ 81
           KMF+GGLSWQTSP+SLRDYF+KFGEI E MVM+DPTT+RSRGFGF+TF DPASVDKVL Q
Sbjct: 2   KMFVGGLSWQTSPESLRDYFNKFGEITEVMVMKDPTTRRSRGFGFITFGDPASVDKVLAQ 181

Query: 82  PHHELDSKTIDPKVAFPRRAQPKMVTRTKKIFVGGLSANTVVEDVKQYFEQFGKVEDAML 141
             HELD K IDPKVAFPRRA P+MVTRTKKIFVGGLSA T +EDVK YFEQFG +EDAML
Sbjct: 182 ATHELDGKKIDPKVAFPRRAHPRMVTRTKKIFVGGLSAPTTLEDVKNYFEQFGPIEDAML 361

Query: 142 MFDKTTNRHRGFGFVTFENE 161
           MFDK TNRHRGFGFVT    
Sbjct: 362 MFDKQTNRHRGFGFVTISKR 421

 Score = 71.2 bits (173), Expect = 6e-13,   Method: Compositional matrix adjust.
 Identities = 35/79 (44%), Positives = 51/79 (64%)
 Frame = +2

Query: 111 KIFVGGLSANTVVEDVKQYFEQFGKVEDAMLMFDKTTNRHRGFGFVTFENEDVVEKVCEI 170
           K+FVGGLS  T  E ++ YF +FG++ + M+M D TT R RGFGF+TF +   V+KV   
Sbjct: 2   KMFVGGLSWQTSPESLRDYFNKFGEITEVMVMKDPTTRRSRGFGFITFGDPASVDKVLAQ 181

Query: 171 HFHEINNKMVECKKAQPKE 189
             HE++ K ++ K A P+ 
Sbjct: 182 ATHELDGKKIDPKVAFPRR 238
>01937
          Length = 1320

 Score =  126 bits (317), Expect(3) = 2e-38,   Method: Compositional matrix adjust.
 Identities = 62/109 (56%), Positives = 77/109 (70%)
 Frame = -1

Query: 61   SRGFGFVTFADPASVDKVLGQPHHELDSKTIDPKVAFPRRAQPKMVTRTKKIFVGGLSAN 120
            +RGFGFVT+ DP++VD VL    H +DSKT              MVT+T KIFVGGLS++
Sbjct: 1320 TRGFGFVTYKDPSNVDNVLANGPHCIDSKT--------------MVTKTSKIFVGGLSSS 1183

Query: 121  TVVEDVKQYFEQFGKVEDAMLMFDKTTNRHRGFGFVTFENEDVVEKVCE 169
            T VED K YF+ +G +E+A LMFDK T+RHRGF FVTF+NE  V+KVCE
Sbjct: 1182 TTVEDXKNYFKAYGTIEEATLMFDKVTSRHRGFAFVTFDNESTVDKVCE 1036

 Score = 45.4 bits (106), Expect(3) = 2e-38,   Method: Compositional matrix adjust.
 Identities = 31/69 (44%), Positives = 37/69 (53%), Gaps = 5/69 (7%)
 Frame = -3

Query: 176  NNKMVECKKAQPKEVMFPPGTRGRARGLP--YTMDAFMLG---MGMLGYPNFVATYGRGY 230
              KMVE KKAQPKEVM  P T  R RGL   Y++  ++ G      L      A YGRG+
Sbjct: 1015 TQKMVETKKAQPKEVMAGPTTLARGRGLAQRYSVAGYLPGPAGFPALPAAAAAAAYGRGF 836

Query: 231  PGFAPSYGY 239
            P   PS+ Y
Sbjct: 835  PALTPSFYY 809

 Score = 25.0 bits (53), Expect(3) = 2e-38,   Method: Compositional matrix adjust.
 Identities = 9/16 (56%), Positives = 12/16 (75%)
 Frame = -2

Query: 163  VVEKVCEIHFHEINNK 178
            +  K  +IHFHEIN+K
Sbjct: 1055 LWTKCVKIHFHEINSK 1008

 Score = 63.2 bits (152), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 28/61 (45%), Positives = 39/61 (63%)
 Frame = -1

Query: 22   KMFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTFADPASVDKVLGQ 81
            K+F+GGLS  T+ +  ++YF  +G I E  +M D  T R RGF FVTF + ++VDKV   
Sbjct: 1212 KIFVGGLSSSTTVEDXKNYFKAYGTIEEATLMFDKVTSRHRGFAFVTFDNESTVDKVCEN 1033

Query: 82   P 82
            P
Sbjct: 1032 P 1030
>03000
          Length = 778

 Score =  151 bits (382), Expect = 3e-37,   Method: Compositional matrix adjust.
 Identities = 74/172 (43%), Positives = 110/172 (63%), Gaps = 2/172 (1%)
 Frame = +3

Query: 22  KMFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTFADPASVDKVLGQ 81
           K+FIGGLS++T  DSLR +F  +GEI +C+VMRD  +KRSRGFGF+T+ D  S+D+    
Sbjct: 90  KLFIGGLSYETDEDSLRSHFETWGEIVDCIVMRDSNSKRSRGFGFITYKDAESIDQAQAN 269

Query: 82  PHHELDSKTIDPKVAFPRRA--QPKMVTRTKKIFVGGLSANTVVEDVKQYFEQFGKVEDA 139
             H++D + +D K A PR    + ++    KK+FVGG+  +T  + ++  F +FG++   
Sbjct: 270 RPHKIDGREVDTKRAMPREESGRSEVQQSVKKMFVGGVKEDTTEDMIRDTFNEFGEITGV 449

Query: 140 MLMFDKTTNRHRGFGFVTFENEDVVEKVCEIHFHEINNKMVECKKAQPKEVM 191
            L+ DK T ++RGF FVTF + D V+K      H++N + VE KKAQ K  M
Sbjct: 450 DLIQDKGTGKNRGFCFVTFGDHDSVDKAVLKKRHDLNGRQVEVKKAQSKNDM 605
>03406
          Length = 1292

 Score =  151 bits (381), Expect = 5e-37,   Method: Compositional matrix adjust.
 Identities = 78/179 (43%), Positives = 106/179 (59%)
 Frame = +3

Query: 9   TSGSANDSQHDPGKMFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVT 68
           T G A +   D  K+F+GGLSW+T    LR+YF KFGE+  C +  D  + +SRGFGFV 
Sbjct: 204 TGGDAEEENEDDRKIFVGGLSWETXSKHLREYFEKFGEVTSCTLKTDLDSGKSRGFGFVV 383

Query: 69  FADPASVDKVLGQPHHELDSKTIDPKVAFPRRAQPKMVTRTKKIFVGGLSANTVVEDVKQ 128
           F + A+VD V+    H+L  + IDPK A PR+         +KIFVG L      EDV+ 
Sbjct: 384 FKEAATVDAVVKNKEHKLQGRKIDPKPANPRKG-------MRKIFVGKLDPGVPQEDVES 542

Query: 129 YFEQFGKVEDAMLMFDKTTNRHRGFGFVTFENEDVVEKVCEIHFHEINNKMVECKKAQP 187
           YF +FGKV +  L +DK  ++ R F FV F+N+  V+KV E   H+I  + V+ KKA P
Sbjct: 543 YFAKFGKVVNVELPYDKVKDQRRAFCFVEFDNDKTVKKVLEQTSHKIGGQEVDVKKATP 719
>26197
          Length = 1365

 Score = 94.4 bits (233), Expect(2) = 1e-29,   Method: Compositional matrix adjust.
 Identities = 42/94 (44%), Positives = 58/94 (61%)
 Frame = -2

Query: 15   DSQHDPGKMFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTFADPAS 74
            +   D  K+F+GGLSW+TS   LR+YF KFGE+  C +  D  + +SRGFGFV F +  +
Sbjct: 1316 EENEDDRKIFVGGLSWETSSKHLREYFEKFGEVTSCTLKTDLDSGKSRGFGFVVFKEAVT 1137

Query: 75   VDKVLGQPHHELDSKTIDPKVAFPRRAQPKMVTR 108
            VD V+    H+L  + IDPK A PR+   K+  R
Sbjct: 1136 VDAVVKNKEHKLQGRKIDPKPANPRKGMRKIFCR 1035

 Score = 53.1 bits (126), Expect(2) = 1e-29,   Method: Compositional matrix adjust.
 Identities = 29/70 (41%), Positives = 41/70 (58%)
 Frame = -3

Query: 111  KIFVGGLSANTVVEDVKQYFEQFGKVEDAMLMFDKTTNRHRGFGFVTFENEDVVEKVCEI 170
            + FVG L      EDV+ YF +FGKV +  L +DK  ++ R F FV F+N+  V+KV E 
Sbjct: 1048 RFFVGKLDPGVPQEDVESYFAKFGKVVNVELPYDKVKDQRRAFCFVEFDNDKTVKKVLEQ 869

Query: 171  HFHEINNKMV 180
              H+I  + V
Sbjct: 868  TSHKIGGQEV 839

 Score = 61.6 bits (148), Expect = 4e-10,   Method: Compositional matrix adjust.
 Identities = 31/82 (37%), Positives = 50/82 (60%)
 Frame = -2

Query: 110  KKIFVGGLSANTVVEDVKQYFEQFGKVEDAMLMFDKTTNRHRGFGFVTFENEDVVEKVCE 169
            +KIFVGGLS  T  + +++YFE+FG+V    L  D  + + RGFGFV F+    V+ V +
Sbjct: 1298 RKIFVGGLSWETSSKHLREYFEKFGEVTSCTLKTDLDSGKSRGFGFVVFKEAVTVDAVVK 1119

Query: 170  IHFHEINNKMVECKKAQPKEVM 191
               H++  + ++ K A P++ M
Sbjct: 1118 NKEHKLQGRKIDPKPANPRKGM 1053

 Score = 43.5 bits (101), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 21/66 (31%), Positives = 34/66 (51%)
 Frame = -3

Query: 21   GKMFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTFADPASVDKVLG 80
            G+ F+G L      + +  YF+KFG++    +  D    + R F FV F +  +V KVL 
Sbjct: 1051 GRFFVGKLDPGVPQEDVESYFAKFGKVVNVELPYDKVKDQRRAFCFVEFDNDKTVKKVLE 872

Query: 81   QPHHEL 86
            Q  H++
Sbjct: 871  QTSHKI 854
>16016
          Length = 1364

 Score =  102 bits (253), Expect(2) = 2e-27,   Method: Compositional matrix adjust.
 Identities = 50/109 (45%), Positives = 71/109 (65%)
 Frame = -2

Query: 22   KMFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTFADPASVDKVLGQ 81
            K+FIGG+   T   SLR YF K+G+IREC+V++DP TKRSR F F+TF +  +VD+V   
Sbjct: 1306 KVFIGGMHPDTDESSLRSYFEKYGDIRECIVVKDPATKRSRCFSFITFGNAENVDEVQKD 1127

Query: 82   PHHELDSKTIDPKVAFPRRAQPKMVTRTKKIFVGGLSANTVVEDVKQYF 130
              H +D +T++ K A PR        +TKK+FVGGL  +T  E +++ F
Sbjct: 1126 RPHTIDGRTVETKRAMPREDTENH-HQTKKMFVGGLKDDTTEEMLRKEF 983

 Score = 37.7 bits (86), Expect(2) = 2e-27,   Method: Compositional matrix adjust.
 Identities = 19/51 (37%), Positives = 31/51 (60%)
 Frame = -1

Query: 141 LMFDKTTNRHRGFGFVTFENEDVVEKVCEIHFHEINNKMVECKKAQPKEVM 191
           ++ DK+T + RGF FV+F++ D V+K       +IN + VE KKA  +  +
Sbjct: 959 MIKDKSTGKFRGFCFVSFDDCDTVDKHAIHKCFKINGRHVEAKKASQQSEL 807

 Score = 65.1 bits (157), Expect = 4e-11,   Method: Compositional matrix adjust.
 Identities = 29/82 (35%), Positives = 52/82 (63%)
 Frame = -2

Query: 108  RTKKIFVGGLSANTVVEDVKQYFEQFGKVEDAMLMFDKTTNRHRGFGFVTFENEDVVEKV 167
            R +K+F+GG+  +T    ++ YFE++G + + +++ D  T R R F F+TF N + V++V
Sbjct: 1315 RNRKVFIGGMHPDTDESSLRSYFEKYGDIRECIVVKDPATKRSRCFSFITFGNAENVDEV 1136

Query: 168  CEIHFHEINNKMVECKKAQPKE 189
             +   H I+ + VE K+A P+E
Sbjct: 1135 QKDRPHTIDGRTVETKRAMPRE 1070

 Score = 31.2 bits (69), Expect(2) = 0.001,   Method: Compositional matrix adjust.
 Identities = 14/45 (31%), Positives = 27/45 (60%)
 Frame = -1

Query: 52  VMRDPTTKRSRGFGFVTFADPASVDKVLGQPHHELDSKTIDPKVA 96
           +++D +T + RGF FV+F D  +VDK       +++ + ++ K A
Sbjct: 959 MIKDKSTGKFRGFCFVSFDDCDTVDKHAIHKCFKINGRHVEAKKA 825

 Score = 28.5 bits (62), Expect(2) = 0.001,   Method: Compositional matrix adjust.
 Identities = 14/35 (40%), Positives = 21/35 (60%)
 Frame = -2

Query: 15   DSQHDPGKMFIGGLSWQTSPDSLRDYFSKFGEIRE 49
            ++ H   KMF+GGL   T+ + LR  F+  G+I E
Sbjct: 1063 ENHHQTKKMFVGGLKDDTTEEMLRKEFT--GKITE 965
>32386
          Length = 674

 Score =  102 bits (255), Expect = 2e-22,   Method: Compositional matrix adjust.
 Identities = 47/100 (47%), Positives = 67/100 (67%), Gaps = 2/100 (2%)
 Frame = +1

Query: 22  KMFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTFADPASVDKVLGQ 81
           K+FIGGLS++T  DSLR +F  +GEI +C+VMRD  +KRSRGFGF+T+ D  S+D+    
Sbjct: 304 KLFIGGLSYETDEDSLRSHFETWGEIVDCIVMRDSNSKRSRGFGFITYKDAESIDQAQAN 483

Query: 82  PHHELDSKTIDPKVAFPRRA--QPKMVTRTKKIFVGGLSA 119
             H++D + +D K A PR    + ++    KK+FVG LS 
Sbjct: 484 RPHKIDGREVDTKRAMPREESGRSEVQQSVKKMFVGSLSC 603

 Score = 65.9 bits (159), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 27/80 (33%), Positives = 54/80 (67%)
 Frame = +1

Query: 110 KKIFVGGLSANTVVEDVKQYFEQFGKVEDAMLMFDKTTNRHRGFGFVTFENEDVVEKVCE 169
           +K+F+GGLS  T  + ++ +FE +G++ D ++M D  + R RGFGF+T+++ + +++   
Sbjct: 301 RKLFIGGLSYETDEDSLRSHFETWGEIVDCIVMRDSNSKRSRGFGFITYKDAESIDQAQA 480

Query: 170 IHFHEINNKMVECKKAQPKE 189
              H+I+ + V+ K+A P+E
Sbjct: 481 NRPHKIDGREVDTKRAMPRE 540
>12350
          Length = 975

 Score = 95.5 bits (236), Expect = 3e-20,   Method: Compositional matrix adjust.
 Identities = 50/161 (31%), Positives = 88/161 (54%)
 Frame = -2

Query: 7   PGTSGSANDSQHDPGKMFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGF 66
           PG     + S+     + + GL W+++ D LR YFS+FG++    V +DP T +S+GFGF
Sbjct: 662 PGPKVVKSSSRQKCSDLIVLGLPWKSTEDDLRSYFSQFGDLLMVQVKKDPKTGQSKGFGF 483

Query: 67  VTFADPASVDKVLGQPHHELDSKTIDPKVAFPRRAQPKMVTRTKKIFVGGLSANTVVEDV 126
           + FA+  S  K + Q  H +D +  D ++   +    +++ R  KIFVG  + +   +D+
Sbjct: 482 IRFAEYESQLKCMAQ-RHMIDGRWCDVRIPNSKEGAQQLMNR--KIFVGRCTDDMTADDL 312

Query: 127 KQYFEQFGKVEDAMLMFDKTTNRHRGFGFVTFENEDVVEKV 167
           +Q+F +FG+V D  +         R F FV+F + +V + +
Sbjct: 311 RQFFSKFGEVVDVFI-----PRPFRAFAFVSFADPEVAQSL 204
>31618
          Length = 716

 Score = 94.4 bits (233), Expect = 6e-20,   Method: Compositional matrix adjust.
 Identities = 50/150 (33%), Positives = 82/150 (54%), Gaps = 2/150 (1%)
 Frame = +1

Query: 22  KMFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTFADPASVDKVLGQ 81
           K+F+GGLSW+T+   LRD+F K+GEI    V  DP T RSRGF F+ F +  ++D+V   
Sbjct: 295 KLFVGGLSWETTEKELRDHFGKYGEIESINVKTDPQTGRSRGFAFIVFTNTEAIDQVSAA 474

Query: 82  PHHELDSKTIDPKVAFPRRAQPKMVTRT--KKIFVGGLSANTVVEDVKQYFEQFGKVEDA 139
             H ++SK +DPK   PR A  + ++    +++ +      +V             + + 
Sbjct: 475 EEHIINSKKVDPKKK-PRLAMARFLSVA*PQRLAMRKSKPTSV---------NLDNIVEV 624

Query: 140 MLMFDKTTNRHRGFGFVTFENEDVVEKVCE 169
            + FDK  +  +GF F+TF++E VV  + +
Sbjct: 625 EMPFDKQKSHRKGFXFITFDSEQVVTDLLK 714

 Score = 63.5 bits (153), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 35/96 (36%), Positives = 58/96 (60%), Gaps = 3/96 (3%)
 Frame = +1

Query: 99  RRAQPKMVTR---TKKIFVGGLSANTVVEDVKQYFEQFGKVEDAMLMFDKTTNRHRGFGF 155
           ++ QP  VT    T+K+FVGGLS  T  ++++ +F ++G++E   +  D  T R RGF F
Sbjct: 250 QKMQPLRVTSVMMTEKLFVGGLSWETTEKELRDHFGKYGEIESINVKTDPQTGRSRGFAF 429

Query: 156 VTFENEDVVEKVCEIHFHEINNKMVECKKAQPKEVM 191
           + F N + +++V     H IN+K V+ KK +P+  M
Sbjct: 430 IVFTNTEAIDQVSAAEEHIINSKKVDPKK-KPRLAM 534

 Score = 33.9 bits (76), Expect = 0.092,   Method: Compositional matrix adjust.
 Identities = 13/35 (37%), Positives = 24/35 (68%)
 Frame = +3

Query: 12  SANDSQHDPGKMFIGGLSWQTSPDSLRDYFSKFGE 46
           S   ++   GK+F+GGL+ + S + ++ YFS+FG+
Sbjct: 507 SQKKAKARHGKIFVGGLTTEISDEEIKTYFSQFGQ 611
>00817
          Length = 2606

 Score = 89.0 bits (219), Expect = 3e-18,   Method: Compositional matrix adjust.
 Identities = 39/78 (50%), Positives = 54/78 (69%)
 Frame = -2

Query: 22   KMFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTFADPASVDKVLGQ 81
            K+FIGG+   T   SLR YF K+G+IREC+V++DP TKRSR F F+TF +  +VD+V   
Sbjct: 2548 KVFIGGMHPDTDESSLRSYFEKYGDIRECIVVKDPATKRSRCFSFITFGNAENVDEVQKD 2369

Query: 82   PHHELDSKTIDPKVAFPR 99
              H +D +T++ K A PR
Sbjct: 2368 RPHTIDGRTVETKRAMPR 2315

 Score = 65.1 bits (157), Expect = 4e-11,   Method: Compositional matrix adjust.
 Identities = 29/82 (35%), Positives = 52/82 (63%)
 Frame = -2

Query: 108  RTKKIFVGGLSANTVVEDVKQYFEQFGKVEDAMLMFDKTTNRHRGFGFVTFENEDVVEKV 167
            R +K+F+GG+  +T    ++ YFE++G + + +++ D  T R R F F+TF N + V++V
Sbjct: 2557 RNRKVFIGGMHPDTDESSLRSYFEKYGDIRECIVVKDPATKRSRCFSFITFGNAENVDEV 2378

Query: 168  CEIHFHEINNKMVECKKAQPKE 189
             +   H I+ + VE K+A P+E
Sbjct: 2377 QKDRPHTIDGRTVETKRAMPRE 2312
>33516
          Length = 449

 Score = 88.2 bits (217), Expect = 4e-18,   Method: Compositional matrix adjust.
 Identities = 42/88 (47%), Positives = 56/88 (63%), Gaps = 10/88 (11%)
 Frame = +1

Query: 17  QHDPGKMFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTFADPASVD 76
           + +PGK+F+GGLSW T  DSL+ YFS+FGEI +C+VM +  T +SRGFGFV+F DP++VD
Sbjct: 142 REEPGKIFVGGLSWDTDQDSLQGYFSQFGEITDCIVMMNQQTGKSRGFGFVSFKDPSTVD 321

Query: 77  KVLGQPH----------HELDSKTIDPK 94
            +L                L  K I PK
Sbjct: 322 VILSSKKPCY*WQNCRCQSLQRKRISPK 405

 Score = 57.8 bits (138), Expect = 6e-09,   Method: Compositional matrix adjust.
 Identities = 25/57 (43%), Positives = 41/57 (71%)
 Frame = +1

Query: 111 KIFVGGLSANTVVEDVKQYFEQFGKVEDAMLMFDKTTNRHRGFGFVTFENEDVVEKV 167
           KIFVGGLS +T  + ++ YF QFG++ D ++M ++ T + RGFGFV+F++   V+ +
Sbjct: 157 KIFVGGLSWDTDQDSLQGYFSQFGEITDCIVMMNQQTGKSRGFGFVSFKDPSTVDVI 327
>02415
          Length = 2763

 Score = 72.4 bits (176), Expect = 3e-13,   Method: Compositional matrix adjust.
 Identities = 32/76 (42%), Positives = 49/76 (64%)
 Frame = -1

Query: 22   KMFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTFADPASVDKVLGQ 81
            K+F+GGL + T+  SLR+YF KFG+I E +V+ D  T +SRG+GFVT AD    D+    
Sbjct: 1923 KIFVGGLPYHTTDHSLREYFDKFGDIDEAVVITDRQTGKSRGYGFVTMADRTGADRACKD 1744

Query: 82   PHHELDSKTIDPKVAF 97
            P+  +D +  +  +A+
Sbjct: 1743 PNPIIDGRKANVNLAY 1696

 Score = 60.1 bits (144), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 25/73 (34%), Positives = 46/73 (63%), Gaps = 5/73 (6%)
 Frame = -1

Query: 102  QPKMVTRTK-----KIFVGGLSANTVVEDVKQYFEQFGKVEDAMLMFDKTTNRHRGFGFV 156
             P ++T  K     KIFVGGL  +T    +++YF++FG +++A+++ D+ T + RG+GFV
Sbjct: 1965 NPALITGQKDTTYTKIFVGGLPYHTTDHSLREYFDKFGDIDEAVVITDRQTGKSRGYGFV 1786

Query: 157  TFENEDVVEKVCE 169
            T  +    ++ C+
Sbjct: 1785 TMADRTGADRACK 1747
>23322
          Length = 471

 Score = 70.5 bits (171), Expect = 9e-13,   Method: Compositional matrix adjust.
 Identities = 34/90 (37%), Positives = 54/90 (60%)
 Frame = -2

Query: 7   PGTSGSANDSQHDPGKMFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGF 66
           P      ++ Q    KMF+GG+   T+ D +RD F++FGEI    +++D  T ++RGF F
Sbjct: 452 PREESGRSEVQQSVKKMFVGGVKEDTTEDMIRDTFNEFGEITGVDLIQDKGTGKNRGFCF 273

Query: 67  VTFADPASVDKVLGQPHHELDSKTIDPKVA 96
           VTF D  SVDK + +  H+L+ + ++ K A
Sbjct: 272 VTFGDHDSVDKAVLKKRHDLNGRQVEVKKA 183

 Score = 67.4 bits (163), Expect = 8e-12,   Method: Compositional matrix adjust.
 Identities = 38/100 (38%), Positives = 58/100 (58%), Gaps = 2/100 (2%)
 Frame = -2

Query: 94  KVAFPRR--AQPKMVTRTKKIFVGGLSANTVVEDVKQYFEQFGKVEDAMLMFDKTTNRHR 151
           K A PR    + ++    KK+FVGG+  +T  + ++  F +FG++    L+ DK T ++R
Sbjct: 464 KRAMPREESGRSEVQQSVKKMFVGGVKEDTTEDMIRDTFNEFGEITGVDLIQDKGTGKNR 285

Query: 152 GFGFVTFENEDVVEKVCEIHFHEINNKMVECKKAQPKEVM 191
           GF FVTF + D V+K      H++N + VE KKAQ K  M
Sbjct: 284 GFCFVTFGDHDSVDKAVLKKRHDLNGRQVEVKKAQSKNDM 165
>11687
          Length = 676

 Score = 68.6 bits (166), Expect = 3e-12,   Method: Compositional matrix adjust.
 Identities = 50/166 (30%), Positives = 78/166 (46%), Gaps = 10/166 (6%)
 Frame = +3

Query: 3   ANGSPGTS-GSANDSQHDPGKMFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRS 61
           +N +P T   S  +   D  KMF+G +      + LR  F  +G +    ++RD  T +S
Sbjct: 93  SNMNPSTQVTSQGEPDADSIKMFVGQIPRNMDENELRKMFEDYGPVHSLNILRDKNTGQS 272

Query: 62  RGFGFVT-FADPASVD--------KVLGQPHHELDSKTIDPKVAFPRRAQPKMVTRTKKI 112
           +G  FVT F   A++D        K +   HH +  K  D +    +R   + V   +K+
Sbjct: 273 KGCCFVTFFTRKAALDAQNALHNVKTMPMMHHPVQMKPADSE----KRNGERNV-EERKL 437

Query: 113 FVGGLSANTVVEDVKQYFEQFGKVEDAMLMFDKTTNRHRGFGFVTF 158
           FVG LS      DV+  FE FG ++D  ++ D +    RG  F+TF
Sbjct: 438 FVGMLSKKLSENDVRMLFESFGSIDDCTVLRD-SNGTSRGCAFITF 572
>24983
          Length = 433

 Score = 66.2 bits (160), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 30/74 (40%), Positives = 46/74 (62%)
 Frame = -2

Query: 24  FIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTFADPASVDKVLGQPH 83
            +GGL + T+  SLR+YF KFG+I E +V+ D  T +SRG+GFVT AD    D+    P+
Sbjct: 306 LLGGLPYHTTDHSLREYFDKFGDIDEAVVITDRQTGKSRGYGFVTMADRTGADRACKDPN 127

Query: 84  HELDSKTIDPKVAF 97
             +D +  +  +A+
Sbjct: 126 PIIDGRKANVNLAY 85

 Score = 51.6 bits (122), Expect = 5e-07,   Method: Compositional matrix adjust.
 Identities = 18/57 (31%), Positives = 38/57 (66%)
 Frame = -2

Query: 113 FVGGLSANTVVEDVKQYFEQFGKVEDAMLMFDKTTNRHRGFGFVTFENEDVVEKVCE 169
            +GGL  +T    +++YF++FG +++A+++ D+ T + RG+GFVT  +    ++ C+
Sbjct: 306 LLGGLPYHTTDHSLREYFDKFGDIDEAVVITDRQTGKSRGYGFVTMADRTGADRACK 136
>17681
          Length = 964

 Score = 65.1 bits (157), Expect = 4e-11,   Method: Compositional matrix adjust.
 Identities = 44/203 (21%), Positives = 88/203 (43%), Gaps = 43/203 (21%)
 Frame = +2

Query: 23  MFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTFADPASVDKVLGQP 82
           +F+G LS +   ++LR+ F+ FGEI  C ++RDP T +S+G+ FV+F   A  +  +   
Sbjct: 38  IFVGDLSPEIETETLREAFAPFGEISNCRIVRDPQTMKSKGYAFVSFVKKAEAENAIQAM 217

Query: 83  HHE-LDSKTIDPKVAFPRRAQPKMVTRTKK------------------------------ 111
           + + + S++I    +  +   P+  +++                                
Sbjct: 218 NGQWIGSRSIRTNWSTRKLPPPRESSKSGGQGGGMGGMGGCGGGAGNGIKNNQRHTFEEV 397

Query: 112 ----------IFVGGLSANTVVEDV-KQYFEQFGKVEDAMLMFDKTTNRHRGFGFVTFEN 160
                     ++ GG   N + +++  ++F QFG ++D  +  DK      GF F+ F  
Sbjct: 398 YNQSSPTNTTVYCGGFPPNVISDELMHKHFMQFGPIQDVRVFKDK------GFAFIKFVT 559

Query: 161 EDVVEKVCE-IHFHEINNKMVEC 182
           ++   +  E  H  E++   V+C
Sbjct: 560 KEAAARAIEHTHISEVHGNHVKC 628
>16427
          Length = 1313

 Score = 62.0 bits (149), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 31/72 (43%), Positives = 43/72 (59%)
 Frame = +1

Query: 20  PGKMFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTFADPASVDKVL 79
           PGK+F+GGL+ +     L   FSKFG I E MV+RD   + SRGFGFVT+ +P   ++ +
Sbjct: 133 PGKLFVGGLAEEIDEKVLEREFSKFGRITESMVIRDKVRQVSRGFGFVTYENPMDAEEAV 312

Query: 80  GQPHHELDSKTI 91
                 +D K I
Sbjct: 313 KH----MDGKEI 336

 Score = 54.3 bits (129), Expect = 7e-08,   Method: Compositional matrix adjust.
 Identities = 29/79 (36%), Positives = 46/79 (58%), Gaps = 1/79 (1%)
 Frame = +1

Query: 108 RTKKIFVGGLSANTVVEDVKQYFEQFGKVEDAMLMFDKTTNRHRGFGFVTFENE-DVVEK 166
           R  K+FVGGL+     + +++ F +FG++ ++M++ DK     RGFGFVT+EN  D  E 
Sbjct: 130 RPGKLFVGGLAEEIDEKVLEREFSKFGRITESMVIRDKVRQVSRGFGFVTYENPMDAEEA 309

Query: 167 VCEIHFHEINNKMVECKKA 185
           V  +   EI  K +  + A
Sbjct: 310 VKHMDGKEILGKKLHVEDA 366
>10194
          Length = 1278

 Score = 56.2 bits (134), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 43/183 (23%), Positives = 84/183 (45%), Gaps = 20/183 (10%)
 Frame = -3

Query: 23  MFIGGLSWQTSPDSLRDYFSKFGEIR----ECMVMRDPTTKR-----SRGF--------G 65
           +F+G +  +T    L   F +FG+I      C  + DPTTK+     ++ F         
Sbjct: 706 VFVGNVPLKTDKKKLARLFKQFGKIENVRFRCAPVGDPTTKKRVAVITKDFHEKRHNISA 527

Query: 66  FVTFADPASVDKVLGQPHHELDSKTIDPKVAFPRRAQPKMVTRTKKIFVGGLSANTVVED 125
           ++ F +  +  + L    H +D   +  +V   + +   +  R+  +FVG L  +   E 
Sbjct: 526 YICFKEDEAAKQALTLNGHVIDG--LHLRVDSAKLSLKNLDKRS--VFVGNLPFDIEEES 359

Query: 126 VKQYFEQFGKVEDAMLMFDKTTNRHRGFGFVTFENEDVVEKVCEIHFHEINNKMV---EC 182
           V+ +FE  G VE+  ++ D+ TN  +G  ++ F++ D V    +++  E+  + +    C
Sbjct: 358 VRSHFEDCGDVENIRVVRDRKTNLGKGICYILFKSADSVSLALKLNNSELEKRQIRVQRC 179

Query: 183 KKA 185
           K A
Sbjct: 178 KDA 170

 Score = 34.3 bits (77), Expect = 0.066,   Method: Compositional matrix adjust.
 Identities = 20/96 (20%), Positives = 43/96 (44%), Gaps = 17/96 (17%)
 Frame = -3

Query: 98  PRRAQPKMVTRTKKIFVGGLSANTVVEDVKQYFEQFGKVED-----------------AM 140
           PRR + +     + +FVG +   T  + + + F+QFGK+E+                 A+
Sbjct: 748 PRRDRLQRANEKRTVFVGNVPLKTDKKKLARLFKQFGKIENVRFRCAPVGDPTTKKRVAV 569

Query: 141 LMFDKTTNRHRGFGFVTFENEDVVEKVCEIHFHEIN 176
           +  D    RH    ++ F+ ++  ++   ++ H I+
Sbjct: 568 ITKDFHEKRHNISAYICFKEDEAAKQALTLNGHVID 461
>02343
          Length = 1715

 Score = 54.3 bits (129), Expect = 8e-08,   Method: Compositional matrix adjust.
 Identities = 53/228 (23%), Positives = 89/228 (39%), Gaps = 14/228 (6%)
 Frame = -2

Query: 23   MFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTFADPASVDKVLGQP 82
            ++I GLS  T+   L +    FG I     + D TT + +G+GFV F  P + ++ +   
Sbjct: 1258 LYIRGLSPNTTDKDLVNLCQHFGTITSTKAIIDQTTNKCKGYGFVDFDAPGAAERAV--- 1088

Query: 83   HHELDSKTIDPKVAFPRRAQPKMVTRTKKIFVGGLSANTVVEDVKQYFEQFGKVEDAMLM 142
               L ++ I  ++A  +   P        +++  L  +   + ++  F+ +G V    ++
Sbjct: 1087 -QALQAQGIQAQMAKQQEQDP------TNLYIANLPLHFTEKHLEGLFKDYGTVISTRIL 929

Query: 143  FDKTTNRHRGFGFVTFENEDVVEKVCEIHFHEINNKMVE-C-------------KKAQPK 188
              K     R  GF   E+ D     C+   +  NNKM+  C             KK   +
Sbjct: 928  -RKPDGISRCVGFARMESRD----KCDTVINTFNNKMISGCSEPLLVKFADSGNKKKSQQ 764

Query: 189  EVMFPPGTRGRARGLPYTMDAFMLGMGMLGYPNFVATYGRGYPGFAPS 236
            + MF     GR  GL +  D        L  P     Y  G P   P+
Sbjct: 763  QKMF---QLGRDDGLQFPFDQQAALAANLSSPYM--NYSMGAPALMPT 635
>23655
          Length = 929

 Score = 39.7 bits (91), Expect(2) = 8e-08,   Method: Compositional matrix adjust.
 Identities = 19/43 (44%), Positives = 26/43 (60%)
 Frame = -3

Query: 149 RHRGFGFVTFENEDVVEKVCEIHFHEINNKMVECKKAQPKEVM 191
           + +GF FVTF + D V+K      H++N + VE KKAQ K  M
Sbjct: 789 QEQGFCFVTFGDHDSVDKAVLKKRHDLNGRQVEVKKAQSKNDM 661

 Score = 34.3 bits (77), Expect(2) = 8e-08,   Method: Compositional matrix adjust.
 Identities = 15/44 (34%), Positives = 28/44 (63%)
 Frame = -1

Query: 110 KKIFVGGLSANTVVEDVKQYFEQFGKVEDAMLMFDKTTNRHRGF 153
           +K+FVGG+  +T  + ++  F +FG++    L+ DK T ++R F
Sbjct: 905 EKMFVGGVKEDTTEDMIRDTFNEFGEITGVDLIQDKGTGKNRDF 774

 Score = 41.2 bits (95), Expect = 6e-04,   Method: Compositional matrix adjust.
 Identities = 18/43 (41%), Positives = 29/43 (67%)
 Frame = -1

Query: 22  KMFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGF 64
           KMF+GG+   T+ D +RD F++FGEI    +++D  T ++R F
Sbjct: 902 KMFVGGVKEDTTEDMIRDTFNEFGEITGVDLIQDKGTGKNRDF 774

 Score = 35.4 bits (80), Expect = 0.030,   Method: Compositional matrix adjust.
 Identities = 17/44 (38%), Positives = 27/44 (61%), Gaps = 2/44 (4%)
 Frame = -3

Query: 55  DPTTK--RSRGFGFVTFADPASVDKVLGQPHHELDSKTIDPKVA 96
           DP  +  + +GF FVTF D  SVDK + +  H+L+ + ++ K A
Sbjct: 810 DPRQRHWQEQGFCFVTFGDHDSVDKAVLKKRHDLNGRQVEVKKA 679
>05273
          Length = 1009

 Score = 49.7 bits (117), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 23/40 (57%), Positives = 30/40 (75%)
 Frame = -1

Query: 32  TSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTFAD 71
           T+  SLR+YF KFG+I E +V+ D  T +SRG+GFVT AD
Sbjct: 166 TTDHSLREYFDKFGDIDEAVVITDRQTGKSRGYGFVTMAD 47

 Score = 41.2 bits (95), Expect = 6e-04,   Method: Compositional matrix adjust.
 Identities = 13/36 (36%), Positives = 28/36 (77%)
 Frame = -1

Query: 126 VKQYFEQFGKVEDAMLMFDKTTNRHRGFGFVTFENE 161
           +++YF++FG +++A+++ D+ T + RG+GFVT  + 
Sbjct: 151 LREYFDKFGDIDEAVVITDRQTGKSRGYGFVTMADR 44
>09968
          Length = 2913

 Score = 47.4 bits (111), Expect = 8e-06,   Method: Compositional matrix adjust.
 Identities = 28/86 (32%), Positives = 45/86 (52%), Gaps = 2/86 (2%)
 Frame = -1

Query: 104  KMVTRTKKIFVGGLSANTVVEDVKQYFEQFGKVEDAMLMFDKTTNRHRGFGFVTFENEDV 163
            K  T  + ++V GLS++T   D+K  F + GKV  A ++ +  +     FGFVT  + D 
Sbjct: 1410 KATTSIRNLWVSGLSSSTRATDLKSLFGKHGKVIGAKVVTNTRSPGRLCFGFVTMASADE 1231

Query: 164  VEKVCEIHFH--EINNKMVECKKAQP 187
              K C  H H  E++ KM+  ++  P
Sbjct: 1230 TTK-CIQHLHRTELHGKMISVERFSP 1156

 Score = 32.0 bits (71), Expect = 0.41,   Method: Compositional matrix adjust.
 Identities = 21/70 (30%), Positives = 31/70 (44%), Gaps = 1/70 (1%)
 Frame = -1

Query: 23   MFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTFADPASVDKVLGQP 82
            +++ GLS  T    L+  F K G++    V+ +  +     FGFVT A      K +   
Sbjct: 1386 LWVSGLSSSTRATDLKSLFGKHGKVIGAKVVTNTRSPGRLCFGFVTMASADETTKCIQHL 1207

Query: 83   HH-ELDSKTI 91
            H  EL  K I
Sbjct: 1206 HRTELHGKMI 1177
>00556
          Length = 2189

 Score = 47.4 bits (111), Expect = 9e-06,   Method: Compositional matrix adjust.
 Identities = 23/69 (33%), Positives = 36/69 (52%)
 Frame = +3

Query: 9   TSGSANDSQHDPGKMFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVT 68
            S    DS H   K+F+GGL    S D +++    FG ++   ++RD  T  S+GF F  
Sbjct: 732 VSTVVQDSDH---KIFMGGLPSYLSEDQMKELLLSFGPLKSFNLVRDNATGLSKGFAFCE 902

Query: 69  FADPASVDK 77
           + DP+  D+
Sbjct: 903 YLDPSVTDQ 929

 Score = 37.0 bits (84), Expect = 0.010,   Method: Compositional matrix adjust.
 Identities = 21/76 (27%), Positives = 37/76 (48%), Gaps = 5/76 (6%)
 Frame = +3

Query: 98  PRRAQPKMVTRT-----KKIFVGGLSANTVVEDVKQYFEQFGKVEDAMLMFDKTTNRHRG 152
           P +A P +V+        KIF+GGL +    + +K+    FG ++   L+ D  T   +G
Sbjct: 708 PTQAVPGVVSTVVQDSDHKIFMGGLPSYLSEDQMKELLLSFGPLKSFNLVRDNATGLSKG 887

Query: 153 FGFVTFENEDVVEKVC 168
           F F  + +  V ++ C
Sbjct: 888 FAFCEYLDPSVTDQAC 935
>17775
          Length = 1282

 Score = 46.2 bits (108), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 41/150 (27%), Positives = 70/150 (46%), Gaps = 20/150 (13%)
 Frame = -2

Query: 60  RSRGFGFVTFADPASVDKVLGQPHHELDSKTIDPKVAFPRRAQPK------MVTRTKKI- 112
           +SRGFGFV+F +P   +K +     E++   +  ++ +  RAQ +      +  R +KI 
Sbjct: 537 KSRGFGFVSFEEPEGAEKAV----DEINGTEVSGRIIYCGRAQKRAERQAELKERFEKIK 370

Query: 113 ------------FVGGLSANTVVEDVKQYFEQFGKVEDAMLMFDKTTNRHRGFGFVTFEN 160
                       +V  L  +   E +++ F  FG +  A +M +    R +GFGFV F +
Sbjct: 369 LERINRYQGVNLYVKNLDDSIDDERLRKEFSNFGTITSAKIMTE--GGRSKGFGFVCFSS 196

Query: 161 -EDVVEKVCEIHFHEINNKMVECKKAQPKE 189
            E+  + V E++   I  K +    AQ KE
Sbjct: 195 PEEATKAVTEMNGRIIVAKPLYVALAQRKE 106
>00302
          Length = 927

 Score = 44.3 bits (103), Expect = 7e-05,   Method: Compositional matrix adjust.
 Identities = 33/99 (33%), Positives = 46/99 (46%), Gaps = 2/99 (2%)
 Frame = -1

Query: 19  DPGKMF-IGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTFADPASVDK 77
           DP +   I GLS  T    LR+ F ++G I E  V+ D  T RSRGF FV F       +
Sbjct: 474 DPNRCLGIFGLSLYTQERGLREVFGRYGHISEVQVVYDRQTGRSRGFAFVYFKSSEDAHE 295

Query: 78  VLGQPHH-ELDSKTIDPKVAFPRRAQPKMVTRTKKIFVG 115
              + +  E+D + I    +   RA     T T  I++G
Sbjct: 294 AKDRCNGIEIDGRKIRVDFSITERAH----TPTPGIYLG 190

 Score = 40.0 bits (92), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 20/66 (30%), Positives = 37/66 (56%), Gaps = 1/66 (1%)
 Frame = -1

Query: 116 GLSANTVVEDVKQYFEQFGKVEDAMLMFDKTTNRHRGFGFVTFE-NEDVVEKVCEIHFHE 174
           GLS  T    +++ F ++G + +  +++D+ T R RGF FV F+ +ED  E     +  E
Sbjct: 447 GLSLYTQERGLREVFGRYGHISEVQVVYDRQTGRSRGFAFVYFKSSEDAHEAKDRCNGIE 268

Query: 175 INNKMV 180
           I+ + +
Sbjct: 267 IDGRKI 250
>02502
          Length = 1557

 Score = 42.7 bits (99), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 24/85 (28%), Positives = 40/85 (47%), Gaps = 1/85 (1%)
 Frame = -3

Query: 112  IFVGGLSANTVVEDVKQYFEQFGKVEDAMLMFDKTTNRHRGFGFVTFENED-VVEKVCEI 170
            ++ GG++     E +   F+ FG + +  +  DK      GF F+ F N+D     +C I
Sbjct: 1435 VYCGGVNNGLTEELMHNTFKDFGSILEVRIFKDK------GFAFIRFNNKDAATNAICTI 1274

Query: 171  HFHEINNKMVECKKAQPKEVMFPPG 195
            H   IN+++V C   +      PPG
Sbjct: 1273 HGTVINDQVVRCSWGKESNEA-PPG 1202
>13457
          Length = 4857

 Score = 42.0 bits (97), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 18/62 (29%), Positives = 32/62 (51%)
 Frame = -1

Query: 22   KMFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTFADPASVDKVLGQ 81
            K+F+G L+ Q + + +R  F  +G I EC ++RD     S+G  FV ++  +     +  
Sbjct: 3405 KLFVGMLNKQQTEEDVRQLFHPYGAIEECTILRD-QNGNSKGCAFVKYSTHSEAQAAINA 3229

Query: 82   PH 83
             H
Sbjct: 3228 LH 3223

 Score = 41.6 bits (96), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 21/60 (35%), Positives = 34/60 (56%), Gaps = 1/60 (1%)
 Frame = -1

Query: 100  RAQPKM-VTRTKKIFVGGLSANTVVEDVKQYFEQFGKVEDAMLMFDKTTNRHRGFGFVTF 158
            R  PKM +   +K+FVG L+     EDV+Q F  +G +E+  ++ D+  N  +G  FV +
Sbjct: 3441 RLTPKMTIGEDRKLFVGMLNKQQTEEDVRQLFHPYGAIEECTILRDQNGN-SKGCAFVKY 3265
>08958
          Length = 680

 Score = 41.6 bits (96), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 39/138 (28%), Positives = 58/138 (42%), Gaps = 1/138 (0%)
 Frame = +2

Query: 22  KMFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTFADPASVDKVLGQ 81
           ++F+G L+   S D  +  FS FGE+ E  V         RGFGF+           L  
Sbjct: 71  RLFVGNLTPDVSEDDFKKLFSPFGEVSEAYV------NSGRGFGFIR----------LDY 202

Query: 82  PHH-ELDSKTIDPKVAFPRRAQPKMVTRTKKIFVGGLSANTVVEDVKQYFEQFGKVEDAM 140
            H+ E     +D      R  + +  T    + V  L      E ++Q F QFG +E A+
Sbjct: 203 RHNAEAAKAALDGLQRKGRSLRVRYATHGAALKVKNLHPYVSNELLEQAFTQFGDLERAI 382

Query: 141 LMFDKTTNRHRGFGFVTF 158
           ++ D+   R  G G V F
Sbjct: 383 VIVDE-RGRSTGEGVVEF 433

 Score = 32.7 bits (73), Expect = 0.20,   Method: Compositional matrix adjust.
 Identities = 17/49 (34%), Positives = 28/49 (57%)
 Frame = +2

Query: 111 KIFVGGLSANTVVEDVKQYFEQFGKVEDAMLMFDKTTNRHRGFGFVTFE 159
           ++FVG L+ +   +D K+ F  FG+V +A +      N  RGFGF+  +
Sbjct: 71  RLFVGNLTPDVSEDDFKKLFSPFGEVSEAYV------NSGRGFGFIRLD 199
>31310
          Length = 469

 Score = 41.2 bits (95), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 19/70 (27%), Positives = 39/70 (55%)
 Frame = -3

Query: 111 KIFVGGLSANTVVEDVKQYFEQFGKVEDAMLMFDKTTNRHRGFGFVTFENEDVVEKVCEI 170
           +I+VG ++     + +KQ F  FG ++   L +D  TN+H+GF F+ ++    V +  ++
Sbjct: 320 RIYVGSINFEIREDTIKQAFLPFGPIKSVNLSWDPITNKHKGFSFIEYD----VPEAAQL 153

Query: 171 HFHEINNKMV 180
              ++N  M+
Sbjct: 152 ALEQMNGVMI 123
>28652
          Length = 918

 Score = 40.8 bits (94), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 31/143 (21%), Positives = 65/143 (45%), Gaps = 5/143 (3%)
 Frame = -2

Query: 22  KMFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTF-ADPASVDKVLG 80
           ++F G +      D L   F   G I +  +M DP +  +RG+ FVT+    A+ + V  
Sbjct: 728 EVFCGKIPRDIFEDELIPLFEDCGTIWDLRLMMDPVSNLNRGYCFVTYTTKEAAAEAVKQ 549

Query: 81  QPHHELDS-KTIDPKVAFPRRAQPKMVTRTKKIFVGGLSANTVVEDVKQYFEQFGKVEDA 139
              +E+   K +   ++ P            ++FVG +  +   E++ + FE+  +    
Sbjct: 548 HDGYEIRKGKKLKVNISIP----------NLRLFVGNIPKSKTKEEILKEFEKHSEGLMD 399

Query: 140 MLMFDKTTN---RHRGFGFVTFE 159
           ++++    N   ++RGF F+ ++
Sbjct: 398 VIVYGSADNPKLKNRGFAFLEYD 330

 Score = 40.4 bits (93), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 32/126 (25%), Positives = 55/126 (43%), Gaps = 4/126 (3%)
 Frame = -2

Query: 50  CMVMRDPTTKRSRGFGFVTFADPASVDKVLGQPHHELDSKTIDPKVAFP----RRAQPKM 105
           C  M++  TK + G       D A +  +L +  +ELD  T   K   P       QP  
Sbjct: 914 CGKMKNLKTKGAGGGAQTKKPDEAKIQAILKRTGYELDVTTGQRKYGGPPPGWTDPQP-- 741

Query: 106 VTRTKKIFVGGLSANTVVEDVKQYFEQFGKVEDAMLMFDKTTNRHRGFGFVTFENEDVVE 165
                ++F G +  +   +++   FE  G + D  LM D  +N +RG+ FVT+  ++   
Sbjct: 740 -GSGHEVFCGKIPRDIFEDELIPLFEDCGTIWDLRLMMDPVSNLNRGYCFVTYTTKEAAA 564

Query: 166 KVCEIH 171
           +  + H
Sbjct: 563 EAVKQH 546
>00029
          Length = 2204

 Score = 40.4 bits (93), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 20/58 (34%), Positives = 28/58 (48%)
 Frame = -3

Query: 22   KMFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTFADPASVDKVL 79
            K+FIG L   T P+ LR  F K+G + EC V+++        FGFV        D  +
Sbjct: 2133 KIFIGNLGDDTDPEELRALFEKYGSVAECDVLKN--------FGFVHMVKKGEADDAI 1984
>39789
          Length = 361

 Score = 37.7 bits (86), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 23/75 (30%), Positives = 37/75 (49%)
 Frame = +1

Query: 23  MFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTFADPASVDKVLGQP 82
           +F+G LS+ T   SL+D F      R   + +   T++ RGFGFV F+ P          
Sbjct: 94  LFVGNLSYDTDQYSLKDAFPGATAAR---IAKFQDTQKPRGFGFVEFSTPDDAASAFDSG 264

Query: 83  HHELDSKTIDPKVAF 97
             E+D + +  K++F
Sbjct: 265 EREVDGRQV--KLSF 303

 Score = 29.6 bits (65), Expect = 1.8,   Method: Compositional matrix adjust.
 Identities = 22/74 (29%), Positives = 33/74 (44%)
 Frame = +1

Query: 109 TKKIFVGGLSANTVVEDVKQYFEQFGKVEDAMLMFDKTTNRHRGFGFVTFENEDVVEKVC 168
           T  +FVG LS +T    +K  F   G     +  F + T + RGFGFV F   D      
Sbjct: 85  TSVLFVGNLSYDTDQYSLKDAFP--GATAARIAKF-QDTQKPRGFGFVEFSTPDDAASAF 255

Query: 169 EIHFHEINNKMVEC 182
           +    E++ + V+ 
Sbjct: 256 DSGEREVDGRQVKL 297
>11126
          Length = 1061

 Score = 37.7 bits (86), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 18/68 (26%), Positives = 36/68 (52%)
 Frame = -3

Query: 97  FPRRAQPKMVTRTKKIFVGGLSANTVVEDVKQYFEQFGKVEDAMLMFDKTTNRHRGFGFV 156
           FP + + K+    + ++VG +      E+++Q+F   G V    ++ DK +   +GF +V
Sbjct: 666 FPSQ-EDKIEADLRSVYVGNVDYGATAEELEQHFHGCGSVNRVTILCDKYSGHPKGFAYV 490

Query: 157 TFENEDVV 164
            F ++D V
Sbjct: 489 EFADKDSV 466

 Score = 33.9 bits (76), Expect = 0.10,   Method: Compositional matrix adjust.
 Identities = 14/59 (23%), Positives = 29/59 (49%)
 Frame = -3

Query: 17  QHDPGKMFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTFADPASV 75
           + D   +++G + +  + + L  +F   G +    ++ D  +   +GF +V FAD  SV
Sbjct: 642 EADLRSVYVGNVDYGATAEELEQHFHGCGSVNRVTILCDKYSGHPKGFAYVEFADKDSV 466
>25691
          Length = 768

 Score = 37.0 bits (84), Expect = 0.012,   Method: Compositional matrix adjust.
 Identities = 18/73 (24%), Positives = 34/73 (46%)
 Frame = -2

Query: 21  GKMFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTFADPASVDKVLG 80
             ++I GL    +   L + F+  G I    ++ D TT  S+G GF+ F      ++ + 
Sbjct: 260 ANLYISGLPKSLTQLDLENLFTDCGNIITSRILYDQTTGLSKGVGFIRFDQRIEAERAIQ 81

Query: 81  QPHHELDSKTIDP 93
           + ++ +    IDP
Sbjct: 80  KLNNHIPDGCIDP 42
>30672
          Length = 877

 Score = 34.7 bits (78), Expect = 0.051,   Method: Compositional matrix adjust.
 Identities = 38/187 (20%), Positives = 70/187 (37%), Gaps = 42/187 (22%)
 Frame = +3

Query: 23  MFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTFADPASVDKVLGQP 82
           +F+  L ++TS + L + F + G ++   V+      + RGFG+V F+      K     
Sbjct: 18  LFVRNLPFETSNEKLLEAFEQVGPLKTAFVVAGKEPGKCRGFGYVQFSMLEDAIKAKDTV 197

Query: 83  HH-----------------------------------ELDSKTI------DPKVAFPRRA 101
            H                                   +L S+T       +PK    +  
Sbjct: 198 THCSGRKISLSFADTKKSWKTKQKGGTETSDALGLGKKLPSQTAVTDGEPNPKPEKKKTK 377

Query: 102 QPKM-VTRTKKIFVGGLSANTVVEDVKQYFEQFGKVEDAMLMFDKTTNRHRGFGFVTFEN 160
           QPK  + +  ++ +  L+      D++ +F +FG + +  +   K  +R RGF FV F  
Sbjct: 378 QPKQELGKRCRLIIRNLAFKCKEADIRSHFGKFGTISEVTIPL-KQGDRSRGFAFVQFTE 554

Query: 161 EDVVEKV 167
               +K 
Sbjct: 555 VKAAQKA 575

 Score = 33.1 bits (74), Expect = 0.16,   Method: Compositional matrix adjust.
 Identities = 18/51 (35%), Positives = 29/51 (56%)
 Frame = +3

Query: 108 RTKKIFVGGLSANTVVEDVKQYFEQFGKVEDAMLMFDKTTNRHRGFGFVTF 158
           ++K +FV  L   T  E + + FEQ G ++ A ++  K   + RGFG+V F
Sbjct: 6   QSKTLFVRNLPFETSNEKLLEAFEQVGPLKTAFVVAGKEPGKCRGFGYVQF 158
>35379
          Length = 534

 Score = 27.3 bits (59), Expect(2) = 0.086,   Method: Compositional matrix adjust.
 Identities = 18/58 (31%), Positives = 32/58 (55%), Gaps = 12/58 (20%)
 Frame = +1

Query: 151 RGFGFVTFENEDVVEKVCEIHFHEINNKMVECKK-----AQPKEVM-------FPPGT 196
           +G+GFVTFEN++  +++ +    E +N + + +K     A  K++M        PPGT
Sbjct: 106 KGYGFVTFENQEDADRIIK---KEADNLIFKDRKLNIGPAVRKQMMPRPYDSNIPPGT 270

 Score = 25.4 bits (54), Expect(2) = 0.086,   Method: Compositional matrix adjust.
 Identities = 9/19 (47%), Positives = 14/19 (73%)
 Frame = +2

Query: 115 GGLSANTVVEDVKQYFEQF 133
           GG++ANT   ++KQYF+  
Sbjct: 2   GGIAANTAETELKQYFQHL 58
>13822
          Length = 963

 Score = 33.1 bits (74), Expect = 0.16,   Method: Compositional matrix adjust.
 Identities = 18/62 (29%), Positives = 35/62 (56%)
 Frame = -1

Query: 125 DVKQYFEQFGKVEDAMLMFDKTTNRHRGFGFVTFENEDVVEKVCEIHFHEINNKMVECKK 184
           D++Q    FG + D  ++F++  ++  GFGFVTF +    E+  +    ++N  +VE +K
Sbjct: 297 DLRQLLGPFGTILDVEIIFNERGSK--GFGFVTFAHSAEAERARD----KMNGTVVEGRK 136

Query: 185 AQ 186
            +
Sbjct: 135 IE 130

 Score = 32.7 bits (73), Expect = 0.22,   Method: Compositional matrix adjust.
 Identities = 17/62 (27%), Positives = 31/62 (50%)
 Frame = -1

Query: 16  SQHDPGKMFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTFADPASV 75
           S   P ++ +  + ++     LR     FG I +  ++ +   + S+GFGFVTFA  A  
Sbjct: 357 SPEGPKRLHVSNIPFRFREADLRQLLGPFGTILDVEIIFN--ERGSKGFGFVTFAHSAEA 184

Query: 76  DK 77
           ++
Sbjct: 183 ER 178
>35180
          Length = 2181

 Score = 32.0 bits (71), Expect = 0.41,   Method: Compositional matrix adjust.
 Identities = 16/58 (27%), Positives = 33/58 (56%), Gaps = 3/58 (5%)
 Frame = -2

Query: 109 TKKIFVGGLSANTVVEDVKQYFEQFGKVEDAMLMFDKTTNRHRGFGFVTF---ENEDV 163
           ++ ++V G   +  ++ + ++FEQ GK++  ++  ++     +G  FVTF   E EDV
Sbjct: 263 SRSVYVKGFPEDITLDTLMEFFEQHGKIDTILMRRNRPDKNFKGSVFVTFSNKEEEDV 90
>28455
          Length = 573

 Score = 31.2 bits (69), Expect = 0.68,   Method: Compositional matrix adjust.
 Identities = 16/53 (30%), Positives = 29/53 (54%)
 Frame = -1

Query: 111 KIFVGGLSANTVVEDVKQYFEQFGKVEDAMLMFDKTTNRHRGFGFVTFENEDV 163
           K+FV  L      E ++  F++ GKV+D  L+  + +   +G  +V FE E++
Sbjct: 537 KLFVKNLPFTCSAEALETIFKEHGKVKDVRLVTYR-SGASKGLAYVEFETEEM 382
>25950
          Length = 417

 Score = 30.8 bits (68), Expect = 0.75,   Method: Compositional matrix adjust.
 Identities = 14/69 (20%), Positives = 33/69 (47%)
 Frame = -2

Query: 97  FPRRAQPKMVTRTKKIFVGGLSANTVVEDVKQYFEQFGKVEDAMLMFDKTTNRHRGFGFV 156
            P   + K    T+ ++VG +      E+++ +F   G +    ++ +K     +GF ++
Sbjct: 320 VPLSLEEKQEIDTRSVYVGNVDYGASAEELEAHFHGCGTINRVTILCNKADGHPKGFAYI 141

Query: 157 TFENEDVVE 165
            F +++ VE
Sbjct: 140 EFGSKEYVE 114
>12096
          Length = 1585

 Score = 30.8 bits (68), Expect = 0.91,   Method: Compositional matrix adjust.
 Identities = 16/55 (29%), Positives = 26/55 (47%)
 Frame = -3

Query: 112  IFVGGLSANTVVEDVKQYFEQFGKVEDAMLMFDKTTNRHRGFGFVTFENEDVVEK 166
            I + GLS   V  D+ Q   + G     +    + T   RGFGFV F+++   ++
Sbjct: 1217 ILLRGLSNTLVENDIIQELIRIGMPPKDVRFMRRVTGASRGFGFVEFQSQSEAQR 1053
>11108
          Length = 493

 Score = 30.4 bits (67), Expect = 0.96,   Method: Compositional matrix adjust.
 Identities = 13/74 (17%), Positives = 40/74 (54%)
 Frame = -1

Query: 104 KMVTRTKKIFVGGLSANTVVEDVKQYFEQFGKVEDAMLMFDKTTNRHRGFGFVTFENEDV 163
           +M+  + K+F+GG+  +   + + Q F+ FG ++      ++   + +G+ ++ FE++  
Sbjct: 310 RMLNYSPKVFLGGIPWDISEQSLIQIFKPFGSIKVEWPGKEQQAAQPKGYVYIIFESDKQ 131

Query: 164 VEKVCEIHFHEINN 177
           V+ +      ++++
Sbjct: 130 VKALLSACVLQVDD 89
>33504
          Length = 282

 Score = 30.4 bits (67), Expect = 1.2,   Method: Composition-based stats.
 Identities = 15/44 (34%), Positives = 24/44 (54%)
 Frame = +1

Query: 12  SANDSQHDPGKMFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRD 55
           S +D   D   +FIGGL +  +   +   FS++GEI    ++RD
Sbjct: 142 SWHDEYKDSAWVFIGGLPYDLTEGDIICVFSQYGEIVNINLVRD 273
>21869
          Length = 503

 Score = 29.6 bits (65), Expect = 1.9,   Method: Compositional matrix adjust.
 Identities = 13/33 (39%), Positives = 20/33 (60%), Gaps = 3/33 (9%)
 Frame = -1

Query: 19  DPGK---MFIGGLSWQTSPDSLRDYFSKFGEIR 48
           DP K   + + GL W+++ D L+ YFS+F   R
Sbjct: 101 DPNKCSDLIVLGLPWKSTEDDLKTYFSQFWRSR 3
>23250
          Length = 1617

 Score = 29.3 bits (64), Expect = 2.5,   Method: Compositional matrix adjust.
 Identities = 14/57 (24%), Positives = 28/57 (49%)
 Frame = -1

Query: 13   ANDSQHDPGKMFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTF 69
            A   + D G +++G +        ++ +FS+FG +    + R   T  S+G+ F+ F
Sbjct: 1359 AKGRKSDRGVVYLGHIPAGFYEPQMKRFFSQFGRVTRLRLSRSTKTGGSKGYAFLEF 1189
>12506
          Length = 1056

 Score = 28.5 bits (62), Expect = 4.2,   Method: Compositional matrix adjust.
 Identities = 15/49 (30%), Positives = 23/49 (46%)
 Frame = -3

Query: 21   GKMFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTF 69
            G +F  G   +     L   F  FG+I +  +  D  T++ RGF F+ F
Sbjct: 1054 GSLFTAG---EVDDKVLHAAFLPFGDIVDIQIPLDYETEKHRGFAFIEF 917
>19556
          Length = 917

 Score = 28.1 bits (61), Expect = 4.9,   Method: Compositional matrix adjust.
 Identities = 14/47 (29%), Positives = 22/47 (46%)
 Frame = -1

Query: 24  FIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTFA 70
           FIGGL    + + L + FS+FG++    +        SR F +V   
Sbjct: 821 FIGGLVKGVTEEELMEKFSRFGQVSNVDIKTRTNGIDSRTFAYVNLT 681
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6671672|ref|NP_031630.1| capping protein (actin
filament) muscle Z-line, alpha 2 [Mus musculus]
         (286 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

01441                                                                 245   1e-65
06308                                                                  31   0.66 
>01441
          Length = 1665

 Score =  245 bits (626), Expect = 1e-65,   Method: Compositional matrix adjust.
 Identities = 114/185 (61%), Positives = 144/185 (77%), Gaps = 2/185 (1%)
 Frame = -1

Query: 103  KEATDPRPYEAENAIESWRTSVETALRAYVKEHYPNGVCTVYGKKVDGQQTIIACIESHQ 162
            KE ++ +  E +   E WR  VE+A+  YV+ HYP+GV TVYG   DG  T+IACIESHQ
Sbjct: 1665 KEGSEYQAAEIDKRAEPWRAEVESAMTTYVQNHYPHGVATVYGSTADGNITLIACIESHQ 1486

Query: 163  FQAKNFWNGRWRSEWKFTVTPS--TTQVVGILKIQVHYYEDGNVQLVSHKDIQDSLTVSN 220
            FQ +N+WNGRWRS+W  T + S  T +V G+LK QVHYYEDGNVQLVS K+I++++ V+ 
Sbjct: 1485 FQPRNYWNGRWRSQWSVTFSESGGTAEVTGVLKAQVHYYEDGNVQLVSSKEIKENVKVTK 1306

Query: 221  EVQTAKEFIKIVEAAENEYQTAISENYQTMSDTTFKALRRQLPVTRTKIDWNKILSYKIG 280
            E  TAK F+ IV  AE++YQTA+SENYQTMSDTTFKALRRQLPVTR+KIDWNKIL YKIG
Sbjct: 1305 EQATAKAFVNIVSQAESDYQTALSENYQTMSDTTFKALRRQLPVTRSKIDWNKILGYKIG 1126

Query: 281  KEMQN 285
             ++++
Sbjct: 1125 GDLKH 1111
>06308
          Length = 926

 Score = 30.8 bits (68), Expect = 0.66,   Method: Compositional matrix adjust.
 Identities = 14/42 (33%), Positives = 22/42 (52%), Gaps = 3/42 (7%)
 Frame = -3

Query: 62  FTPVKIEGYEDQVLITEHGDL--GNGKFLDPK-NRICFKFDH 100
           F P+   G++D  +I  H DL     +FL P   R+C++  H
Sbjct: 456 FNPLPTNGHDDDAMIALHSDL*YCXSRFLKPSVQRLCWRTRH 331
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|94374531|ref|XP_001002822.1| PREDICTED: similar to
Signal recognition particle 72 kDa protein (SRP72) isoform 17 [Mus
musculus]
         (440 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

10690                                                                 246   1e-65
>10690
          Length = 1300

 Score =  246 bits (629), Expect = 1e-65,   Method: Compositional matrix adjust.
 Identities = 133/304 (43%), Positives = 192/304 (63%), Gaps = 3/304 (0%)
 Frame = -2

Query: 1   MAYIMQLQGRTEEALQLYNQIIKLKPTDVALLAVIANNIITINKDQNVFDSKKKVKLTNA 60
           M Y++Q +GRTEEA QLYN + K +P+DV L AV++NNI+T+NK+QNVFDSK+K+K    
Sbjct: 963 MGYLLQREGRTEEASQLYNLVQKNRPSDVGLGAVLSNNIVTVNKEQNVFDSKRKMKAATG 784

Query: 61  EGVEFKLSKRQLQAIEFNKALLAMYTNQAEQCRKIAASLQSQSPEYLLPVLIQAAQLCRE 120
           +  + KL+  Q + I  N+ LL MY+NQ EQC K    L   SP     +LI  AQ  ++
Sbjct: 783 DSAKAKLTAAQRETITLNQCLLHMYSNQGEQCLKETERLLQTSPSLTPCLLISVAQHAKD 604

Query: 121 KQHTKAIELLQEFSDQHPENAAEIKLTMAQLKISQGNISKACLILRSIEELRHKPGMVSA 180
           K   KAI LLQ + + H +    ++LT  Q+ +SQG +  AC  L+++ +L++KPG+VSA
Sbjct: 603 KNVDKAIXLLQAYGEXHQDLQFSMQLTKVQIYLSQGKVYAACEALKALGDLQYKPGVVSA 424

Query: 181 LVTMYSHEEDIDSAIEVFTQAIQWYQSHQPKSPAHLSLIREAANFKLKYGRKKEAVSDLE 240
           LVT+Y  +ED  +A E    A+ WY+  QPKSP    L +  ++F++K+G  + A   LE
Sbjct: 423 LVTLYMSQEDTTAASETLITAVNWYKKQQPKSPDLAVLTQANSSFQMKHGNPQVAAQTLE 244

Query: 241 QLWKQNSKDIHTLAQLISAYSLVDPEKAKALSKHLPSSDSMSLKVDVEALE---NSPGAT 297
              K+N KD   LAQLISAYS  D  KAK +SK LP    ++  VDV++LE   ++ G  
Sbjct: 243 DQRKRNPKDPLILAQLISAYSHFDTAKAKEVSKDLPPVSEIAQGVDVDSLETTFSTLGPK 64

Query: 298 YIRK 301
           Y++K
Sbjct: 63  YMKK 52
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|148747177|ref|NP_077756.2| RAB22A, member RAS
oncogene family [Mus musculus]
         (194 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

08428                                                                 244   2e-65
33374                                                                 135   4e-39
26083                                                                 113   6e-26
34468                                                                 109   6e-25
14456                                                                 102   8e-23
17511                                                                 101   2e-22
01095                                                                  98   2e-21
07465                                                                  89   9e-19
01398                                                                  89   9e-19
05468                                                                  87   4e-18
07580                                                                  86   9e-18
32723                                                                  84   5e-17
33380                                                                  83   9e-17
13901                                                                  80   5e-16
29380                                                                  79   1e-15
33794                                                                  79   1e-15
30760                                                                  79   2e-15
01972                                                                  64   5e-15
11257                                                                  73   6e-14
12339                                                                  69   1e-12
35581                                                                  69   1e-12
13750                                                                  67   4e-12
26536                                                                  67   4e-12
09204                                                                  65   2e-11
13745                                                                  65   3e-11
11728                                                                  62   1e-10
34359                                                                  60   5e-10
14119                                                                  60   6e-10
19006                                                                  60   7e-10
27191                                                                  57   7e-09
00858                                                                  55   1e-08
19656                                                                  55   2e-08
00552                                                                  53   8e-08
08153                                                                  53   9e-08
25618                                                                  52   1e-07
34597                                                                  52   1e-07
31291                                                                  51   3e-07
09827                                                                  51   3e-07
19046                                                                  50   8e-07
24619                                                                  47   4e-06
17872                                                                  47   7e-06
18208                                                                  43   7e-05
33605                                                                  43   7e-05
14775                                                                  42   2e-04
18509                                                                  38   0.003
10862                                                                  37   0.005
10708                                                                  32   0.13 
25697                                                                  29   1.1  
15478                                                                  28   2.3  
07633                                                                  27   4.0  
22347                                                                  27   4.2  
06884                                                                  27   5.5  
>08428
          Length = 1109

 Score =  244 bits (622), Expect = 2e-65,   Method: Compositional matrix adjust.
 Identities = 112/192 (58%), Positives = 152/192 (79%)
 Frame = -3

Query: 1    MALRELKVCLLGDTGVGKSSIVWRFVEDSFDPNINPTIGASFMTKTVQYQNELHKFLIWD 60
            M +R++KVCLLGD+GVGKSSIV RFV  S+ P+   TIGASFM+K++      ++F IWD
Sbjct: 1083 MQMRDVKVCLLGDSGVGKSSIVLRFVTGSYRPSQESTIGASFMSKSLVVDGAGYRFQIWD 904

Query: 61   TAGQERFRALAPMYYRGSAAAIIVYDITKEETFSTLKNWVRELRQHGPPSIVVAIAGNKC 120
            TAGQE+FRALAPMYYRG+AAA+IVYD+T+  TF ++K+W++ELR  GPP+IV+AIAGNKC
Sbjct: 903  TAGQEKFRALAPMYYRGAAAAVIVYDVTRPRTFKSVKSWIQELRSFGPPNIVLAIAGNKC 724

Query: 121  DLTDVREVMERDAKDYADSIHAIFVETSAKNAININELFIEISRRIPSTDANPASGGKGF 180
            DL ++REV+E+DA++YA SI AIF ETSA  A+N+ E+F E++R++P  + NP       
Sbjct: 723  DLEELREVVEKDAQEYASSISAIFGETSAMTAVNVEEMFTELARQLPPEEDNPHPSNT-V 547

Query: 181  KLRRQPSEPKRS 192
             LRRQPS+ ++S
Sbjct: 546  NLRRQPSKSEQS 511
>33374
          Length = 489

 Score =  135 bits (340), Expect(2) = 4e-39,   Method: Compositional matrix adjust.
 Identities = 62/117 (52%), Positives = 87/117 (74%)
 Frame = +1

Query: 42  FMTKTVQYQNELHKFLIWDTAGQERFRALAPMYYRGSAAAIIVYDITKEETFSTLKNWVR 101
           F+T+TV   +   KF IWDTAGQER+ +LAPMYYRG+ AAI+VYDIT ++TF   K WV+
Sbjct: 139 FLTQTVCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNQDTFGRAKTWVK 318

Query: 102 ELRQHGPPSIVVAIAGNKCDLTDVREVMERDAKDYADSIHAIFVETSAKNAININEL 158
           EL++   P+IV+A+AGNK DL + R V   +A+ YA+    +F+ETSAK A+N+N++
Sbjct: 319 ELQRQASPNIVIALAGNKADLANKRMVEFEEAQAYAEENSLLFMETSAKTAMNVNDI 489

 Score = 42.7 bits (99), Expect(2) = 4e-39,   Method: Compositional matrix adjust.
 Identities = 19/38 (50%), Positives = 26/38 (68%)
 Frame = +2

Query: 5  ELKVCLLGDTGVGKSSIVWRFVEDSFDPNINPTIGASF 42
          + K+ LLG++ VGKSS+V RFV+  F      TIGA+F
Sbjct: 29 QFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAF 142
>26083
          Length = 432

 Score =  113 bits (282), Expect = 6e-26,   Method: Compositional matrix adjust.
 Identities = 48/117 (41%), Positives = 74/117 (63%)
 Frame = +1

Query: 3   LRELKVCLLGDTGVGKSSIVWRFVEDSFDPNINPTIGASFMTKTVQYQNELHKFLIWDTA 62
           LR+ K+  LG+  VGK+S++ RF+ DSFD     TIG  F++KT+  ++   +  +WDTA
Sbjct: 70  LRKFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTIRLQLWDTA 249

Query: 63  GQERFRALAPMYYRGSAAAIIVYDITKEETFSTLKNWVRELRQHGPPSIVVAIAGNK 119
           GQERFR+L P Y R S+ A++VYDIT   +F     W+ ++R      +++ + GNK
Sbjct: 250 GQERFRSLIPSYIRDSSVAVVVYDITNANSFHQTSKWIDDVRTERGSDVIIMLVGNK 420
>34468
          Length = 1502

 Score =  109 bits (273), Expect = 6e-25,   Method: Compositional matrix adjust.
 Identities = 58/171 (33%), Positives = 95/171 (55%), Gaps = 5/171 (2%)
 Frame = +1

Query: 4   RELKVCLLGDTGVGKSSIVWRFVEDSFDPNINPTIGASFMTKTVQYQNELHKFLIWDTAG 63
           R  K+ ++GD+ VGK+ + +RF    F      TIG  F  K++Q  +E  K  +WDTAG
Sbjct: 490 RIFKIIVIGDSNVGKTCLTYRFCLGKFPDKTEATIGVDFREKSIQVDSEHLKLQLWDTAG 669

Query: 64  QERFR-ALAPMYYRGSAAAIIVYDITKEETFSTLKNWVRELRQHGPPSIVVAI-AGNKCD 121
           QERFR ++   YYR   A + VYD+TK  +F  +  W+ E  +H     +  I  GNKCD
Sbjct: 670 QERFRKSMVQHYYRNVHAVVFVYDMTKMSSFENMPAWIEECDRHNLTKYIPRILVGNKCD 849

Query: 122 LTDVREVMERDAKDYADSIHAIFVETSAKN---AININELFIEISRRIPST 169
           + +   V    A+ +AD+ +    ETSAK+   A +++ +F+ ++ ++  +
Sbjct: 850 VVERIAVNTNLAQKFADAHNMPLFETSAKDDEKANHVDAIFMTVAHKLKXS 1002
>14456
          Length = 1867

 Score =  102 bits (255), Expect = 8e-23,   Method: Compositional matrix adjust.
 Identities = 64/205 (31%), Positives = 103/205 (50%), Gaps = 11/205 (5%)
 Frame = -1

Query: 1    MALRELKVCL---LGDTGVGKSSIVWRFVEDSFDPNINPTIGASFMTKTVQYQNELHKFL 57
            +A   LK+ L   L   GVGKSS++ RFV + FD     TIG  F+ K V   +E +   
Sbjct: 1162 LACVWLKITLDKQLKQGGVGKSSLMNRFVSNKFDAQSFHTIGVEFLNKDVVVDDETYTMQ 983

Query: 58   IWDTAGQERFRALAPMYYRGSAAAIIVYDITKEETFSTLKNWVRELRQHGP----PSIVV 113
            IWDTAGQERF++L   +YRG+   ++ + +   ++F  L  W +E   +       +   
Sbjct: 982  IWDTAGQERFKSLRTPFYRGADCCLLTFSVDSMQSFRNLSMWRKEFLYYADIQDGVTFPF 803

Query: 114  AIAGNKCDLTDVREVMERDAKDYADS-IHAIFVETSAKNAININELFIEISRRIPSTDAN 172
             + GNK D+ + R+V   +A+ +  +  +A + ETSAK+A N+ + F+   +R+   +  
Sbjct: 802  VVLGNKIDV-EGRQVTNEEARSWCTANSNAPYFETSAKDATNVEKAFLAAVQRLREVEDQ 626

Query: 173  ---PASGGKGFKLRRQPSEPKRSCC 194
                 + G    L R       SCC
Sbjct: 625  QEVKTAHGNTVDLNRAARGKSSSCC 551
>17511
          Length = 483

 Score =  101 bits (251), Expect = 2e-22,   Method: Compositional matrix adjust.
 Identities = 50/121 (41%), Positives = 71/121 (58%), Gaps = 4/121 (3%)
 Frame = -3

Query: 6   LKVCLLGDTGVGKSSIVWRFVEDSFDPNINPTIGASFMTKTVQYQNELHKFLIWDTAGQE 65
           LKV +LGD+GVGK+S++ ++V   F      TIGA F+TK V   + L    IWDTAGQE
Sbjct: 364 LKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQIWDTAGQE 185

Query: 66  RFRALAPMYYRGSAAAIIVYDITKEETFSTLKNWVRELRQHGPP----SIVVAIAGNKCD 121
           RF++L   +YRG+   ++V+D+T   TF +L +W  E      P    +    + GNK D
Sbjct: 184 RFQSLGVAFYRGADCCVLVFDVTMPNTFRSLDSWRDEFLIQASPRDPENFPFVVIGNKID 5

Query: 122 L 122
           L
Sbjct: 4   L 2
>01095
          Length = 1745

 Score = 98.2 bits (243), Expect = 2e-21,   Method: Compositional matrix adjust.
 Identities = 46/117 (39%), Positives = 74/117 (63%), Gaps = 5/117 (4%)
 Frame = -1

Query: 83   IVYDITKEETFSTLKNWVRELRQHGPPSIVVAIAGNKCDLTDVREVMERDAKDYADSIHA 142
            +VYDIT ++TF   K WV+EL++   P+IV+A+AGNK DL + R V   +A+ YA+    
Sbjct: 1745 VVYDITNQDTFGRAKTWVKELQRQASPNIVIALAGNKADLANKRMVEFEEAQAYAEENSL 1566

Query: 143  IFVETSAKNAININELFIEISRRIPSTDANPASGG-----KGFKLRRQPSEPKRSCC 194
            +F+ETSAK A+N+N++F+ I++++P    N   GG     +G +L  + S+     C
Sbjct: 1565 LFMETSAKTAMNVNDIFLAIAKKLPK---NEGGGGSQPRQQGVRLNNEQSQQSEGGC 1404
>07465
          Length = 1103

 Score = 89.4 bits (220), Expect = 9e-19,   Method: Compositional matrix adjust.
 Identities = 44/141 (31%), Positives = 75/141 (53%)
 Frame = +3

Query: 19  SSIVWRFVEDSFDPNINPTIGASFMTKTVQYQNELHKFLIWDTAGQERFRALAPMYYRGS 78
           SS++ R+ +  F  +   TIG  F+ + ++   E  + ++WDTAGQE F A+   YYRG+
Sbjct: 240 SSMIQRYCKGIFTKDYKKTIGVDFLERQIEVGGEDVRLMLWDTAGQEEFDAITKAYYRGA 419

Query: 79  AAAIIVYDITKEETFSTLKNWVRELRQHGPPSIVVAIAGNKCDLTDVREVMERDAKDYAD 138
            A ++ +     ++F  L+ W R++       I + I  NK DL D   V   +A++ A 
Sbjct: 420 QACVLAFSTVDRDSFEALETWKRKVEDE-VGEIGMVIVQNKIDLIDDAVVRPEEAENLAK 596

Query: 139 SIHAIFVETSAKNAININELF 159
            +   F  TS K  +N++E+F
Sbjct: 597 KLRLRFYRTSVKENMNVDEVF 659
>01398
          Length = 1421

 Score = 89.4 bits (220), Expect = 9e-19,   Method: Compositional matrix adjust.
 Identities = 44/102 (43%), Positives = 60/102 (58%), Gaps = 1/102 (0%)
 Frame = -2

Query: 64   QERFRALAPMYYRGSAAAIIVYDITKEETFSTLKNWVRELRQH-GPPSIVVAIAGNKCDL 122
            QERFR++   YYR S   IIVYDITK  TF  LK W  E R H  P   +  + G+K D 
Sbjct: 1420 QERFRSITRSYYRNSVGVIIVYDITKRSTFENLKQWYEEARNHIEPHKAIFLVLGHKSDR 1241

Query: 123  TDVREVMERDAKDYADSIHAIFVETSAKNAININELFIEISR 164
             D R+V  R+ + +A+     F ETSAK+  NI ++F +I++
Sbjct: 1240 EDARQVTAREGRRFAEMHGLKFFETSAKSGHNIEDVFAQIAK 1115
>05468
          Length = 1558

 Score = 87.0 bits (214), Expect = 4e-18,   Method: Compositional matrix adjust.
 Identities = 57/172 (33%), Positives = 84/172 (48%), Gaps = 8/172 (4%)
 Frame = -3

Query: 7    KVCLLGDTGVGKSSIVWRFVEDSFDPNINPTIGASFMTKTVQYQ-NELHKFLIWDTAGQE 65
            K+ ++G+ G GK+SI+ R+V   F  +   TIG  F  K + +  + L +  +WD AGQE
Sbjct: 1535 KILVIGELGTGKTSIIKRYVHQFFSQHYRATIGVDFALKVLNWDADTLIRLQLWDIAGQE 1356

Query: 66   RFRALAPMYYRGSAAAIIVYDITKEETFSTLKNWVRELRQH-----GPPSIVVAIAGNKC 120
            RF  +  +YY+ +  A +V+D+T+  TF  +  W  +L        G P   V +A NKC
Sbjct: 1355 RFGNMTRVYYKEAVGAFVVFDVTRASTFDAVTKWKNDLDSKVQLADGSPVPCVLLA-NKC 1179

Query: 121  DLTDVREVMERDAKDYADSIHAI--FVETSAKNAININELFIEISRRIPSTD 170
            D      V      D   S      + ETSAK  INI+E    +  RI   D
Sbjct: 1178 DQAKEGLVNNTSQMDEFCSEKGFIGWYETSAKENINIDEAARFLVTRILEKD 1023
>07580
          Length = 921

 Score = 85.9 bits (211), Expect = 9e-18,   Method: Compositional matrix adjust.
 Identities = 54/165 (32%), Positives = 84/165 (50%), Gaps = 1/165 (0%)
 Frame = +3

Query: 30  FDPNINPTIGASFMTKTVQYQNELHKFLIWDTAGQERFRALAPMYYRGSAAAIIVYDITK 89
           F    +PTI  S+  K V+   +     I DTAG E+F A+  +Y +     ++ Y IT 
Sbjct: 135 FVEKYDPTIEDSY-RKQVEVDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFLLAYSITA 311

Query: 90  EETFSTLKNWVRE-LRQHGPPSIVVAIAGNKCDLTDVREVMERDAKDYADSIHAIFVETS 148
           + TF+ L+    + LR      + + + GNKCDL D R V +   +  A S    F+ETS
Sbjct: 312 QSTFNDLQELREQILRVKDTDDVPMLLVGNKCDLEDERVVGKDQGQGLARSFSCAFLETS 491

Query: 149 AKNAININELFIEISRRIPSTDANPASGGKGFKLRRQPSEPKRSC 193
           AK  IN+NE+F+++ R+I     +P   GK        ++ K+SC
Sbjct: 492 AKARINVNEIFMDLVRQINK--KSPEQSGK-------RTKSKKSC 599
>32723
          Length = 384

 Score = 83.6 bits (205), Expect = 5e-17,   Method: Compositional matrix adjust.
 Identities = 37/105 (35%), Positives = 64/105 (60%)
 Frame = +2

Query: 64  QERFRALAPMYYRGSAAAIIVYDITKEETFSTLKNWVRELRQHGPPSIVVAIAGNKCDLT 123
           QERFR++   YYR + A I+VYD+  ++++ +L  W+ E+  +    ++  + GNK D T
Sbjct: 2   QERFRSITQSYYRSANALILVYDVCSQQSYESLPQWIHEIELYAGTKVLAFLVGNKIDQT 181

Query: 124 DVREVMERDAKDYADSIHAIFVETSAKNAININELFIEISRRIPS 168
           D RE+     K++A+     F+ETSAK A N+ +LF  I+ ++ +
Sbjct: 182 DKREIPTHIGKEFAERYEMRFLETSAKEADNVEKLFSTIAYQLTA 316
>33380
          Length = 282

 Score = 82.8 bits (203), Expect = 9e-17,   Method: Compositional matrix adjust.
 Identities = 35/81 (43%), Positives = 54/81 (66%)
 Frame = +3

Query: 46  TVQYQNELHKFLIWDTAGQERFRALAPMYYRGSAAAIIVYDITKEETFSTLKNWVRELRQ 105
           TV  Q++  K  IWDTAGQER+R +   YYRG+   I++YD+T EE+F+ +++W  +++ 
Sbjct: 36  TVFRQDKRVKLQIWDTAGQERYRTITTAYYRGAMGFILMYDVTNEESFNAVQDWCTQIKT 215

Query: 106 HGPPSIVVAIAGNKCDLTDVR 126
           +   +  V + GNKCDL D R
Sbjct: 216 YSWDNAQVVLVGNKCDLEDER 278
>13901
          Length = 962

 Score = 80.1 bits (196), Expect = 5e-16,   Method: Compositional matrix adjust.
 Identities = 36/95 (37%), Positives = 60/95 (63%), Gaps = 1/95 (1%)
 Frame = -3

Query: 6   LKVCLLGDTGVGKSSIVWRFVEDSFDPNINPTIGASFMTKTVQYQNELH-KFLIWDTAGQ 64
            KV ++GD  VGK+S V R+V DSF  +   TIG  F  K +++ ++ + K  +WD AGQ
Sbjct: 285 FKVIIIGDPTVGKTSFVQRYVNDSFRRDYKMTIGVDFALKVIRWSDKCNIKLQLWDIAGQ 106

Query: 65  ERFRALAPMYYRGSAAAIIVYDITKEETFSTLKNW 99
           ERF ++  +YY+ + A I+++D+T++ T+     W
Sbjct: 105 ERFTSMTRVYYKDAHACIVMFDLTQKNTYQNAIRW 1
>29380
          Length = 853

 Score = 78.6 bits (192), Expect = 1e-15,   Method: Compositional matrix adjust.
 Identities = 43/118 (36%), Positives = 67/118 (56%), Gaps = 1/118 (0%)
 Frame = -2

Query: 78  SAAAIIVYDITKEETFSTLKNWVRELRQHGPPSIVVAIAGNKCDL-TDVREVMERDAKDY 136
           ++AAIIVYD+   +TFS    WV+ELRQ    S+++ +AGNK DL T  R V   DA+ +
Sbjct: 852 ASAAIIVYDVNIADTFSRALAWVKELRQQNTESVLIILAGNKVDLATQHRAVSFEDAQSF 673

Query: 137 ADSIHAIFVETSAKNAININELFIEISRRIPSTDANPASGGKGFKLRRQPSEPKRSCC 194
           A     +F E SAK  + +NE+F+ ++ ++   + +  S  +G  L R+  E     C
Sbjct: 672 ARENGLLFAEVSAKTGMAVNEIFMTLANQLIQQEID-GSRNRGVTLNRENGEASGCKC 502
>33794
          Length = 779

 Score = 78.6 bits (192), Expect = 1e-15,   Method: Compositional matrix adjust.
 Identities = 42/124 (33%), Positives = 66/124 (53%)
 Frame = -1

Query: 41  SFMTKTVQYQNELHKFLIWDTAGQERFRALAPMYYRGSAAAIIVYDITKEETFSTLKNWV 100
           ++ T T+  + +  K  IWDT+GQ RF  +   Y RG+   I+VYDIT + +F  +  W+
Sbjct: 689 AYKTTTILLEGKRVKLQIWDTSGQGRFCTIIRSYSRGAQGIILVYDITNKWSFDGIDRWL 510

Query: 101 RELRQHGPPSIVVAIAGNKCDLTDVREVMERDAKDYADSIHAIFVETSAKNAININELFI 160
           +E+ +H  P I   + GN+  L   R+V  + A+ YA   +    E S     NI E F 
Sbjct: 509 KEVEEHA-PGIPKVLVGNRLHLAYKRQVAAKQAETYASRNNMSCFEISPLCDFNIRESFC 333

Query: 161 EISR 164
           E++R
Sbjct: 332 ELAR 321
>30760
          Length = 596

 Score = 78.6 bits (192), Expect = 2e-15,   Method: Compositional matrix adjust.
 Identities = 54/162 (33%), Positives = 79/162 (48%), Gaps = 8/162 (4%)
 Frame = -1

Query: 7   KVCLLGDTGVGKSSIVWRFVEDS--FDPNINPTIGASFMTKTVQY-----QNELHKFLIW 59
           K  + GD+GVGKSSI   F  DS  F  N + T G   + K V       Q EL+ F   
Sbjct: 524 KCIVTGDSGVGKSSICQVFHSDSAHFPKNYSMTTGVEVLVKLVNIPDSRDQVELYLF--- 354

Query: 60  DTAGQERFRALAPMYYRGSAAAIIVYDITKEETFSTLKNWVRELRQHGPPSIVVAI-AGN 118
           D+AG+E F      ++   +  ++VYD+T E +FS    W+  +R   P +++  +   N
Sbjct: 353 DSAGKEIFSENVTKFWDQPSVVMVVYDVTDETSFSGCVRWLERVRAAKPNTVIPGVLVAN 174

Query: 119 KCDLTDVREVMERDAKDYADSIHAIFVETSAKNAININELFI 160
           K DL + R V  ++ KD A S    + E SAK   N +  F 
Sbjct: 173 KTDLDERRRVSRKEGKDLAQSHGLEYFECSAKEMQNTDTPFF 48
>01972
          Length = 2359

 Score = 63.9 bits (154), Expect(2) = 5e-15,   Method: Compositional matrix adjust.
 Identities = 37/112 (33%), Positives = 64/112 (57%)
 Frame = +3

Query: 55  KFLIWDTAGQERFRALAPMYYRGSAAAIIVYDITKEETFSTLKNWVRELRQHGPPSIVVA 114
           KF +WDTAGQE+F  L   YY     A+I++D+T   T+  + NW R+L +    +I + 
Sbjct: 450 KFNVWDTAGQEKFGGLRDGYYIQGQCAVIMFDVTSRVTYKNVPNWHRDLVRVC-ENIPIV 626

Query: 115 IAGNKCDLTDVREVMERDAKDYADSIHAIFVETSAKNAININELFIEISRRI 166
           + GNK D+ D R+V  + A  +    +  + + SAK+  N  + F+ ++R++
Sbjct: 627 LCGNKVDIKD-RKVKAK-AIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKL 776

 Score = 33.1 bits (74), Expect(2) = 5e-15,   Method: Compositional matrix adjust.
 Identities = 14/31 (45%), Positives = 20/31 (64%)
 Frame = +1

Query: 6   LKVCLLGDTGVGKSSIVWRFVEDSFDPNINP 36
            K+ L+GD GVGK++ V R V   F+ N+ P
Sbjct: 304 FKLVLVGDGGVGKTTFVKRHVTGEFEKNMLP 396
>11257
          Length = 1102

 Score = 73.2 bits (178), Expect = 6e-14,   Method: Compositional matrix adjust.
 Identities = 40/131 (30%), Positives = 69/131 (52%), Gaps = 5/131 (3%)
 Frame = -2

Query: 45   KTVQYQNELHKFLIWDTAGQERFRALAPMYYRGSAAAIIVYDITKEETFSTLKNWVRELR 104
            K V    E     IWDTAGQER+++L   +YRG+   ++ + +   ++  +L +W  E  
Sbjct: 1053 KDVVVDGETFTMQIWDTAGQERYKSLRTPFYRGTDCCLLTFSVDNLKSLQSLSDWYDEFV 874

Query: 105  QHG----PPSIVVAIAGNKCDLTDVREVMERDAKDYADSIHAI-FVETSAKNAININELF 159
             +       S    I GNK D+ + REV   DA ++  +   + + ETSAK+++N+ + F
Sbjct: 873  NYADIQDSASFPFVIIGNKADIEE-REVSSEDAYNWCRTHGNLPYFETSAKDSLNVQQAF 697

Query: 160  IEISRRIPSTD 170
            + + RR+   D
Sbjct: 696  LAVVRRLREMD 664
>12339
          Length = 578

 Score = 68.9 bits (167), Expect = 1e-12,   Method: Compositional matrix adjust.
 Identities = 38/106 (35%), Positives = 59/106 (55%), Gaps = 5/106 (4%)
 Frame = -2

Query: 64  QERFRALAPMYYRGSAAAIIVYDITKEETFSTLKNWVRELRQHGPP----SIVVAIAGNK 119
           QERF++L   +YRG+   I+VYD+T+ +TF +L +W RE      P         + GNK
Sbjct: 577 QERFQSLGVAFYRGADCCILVYDVTEXKTFDSLDSWQREFLNQASPRDPEHFPFVVIGNK 398

Query: 120 CDLTDVREVMERDAKDYADSIHAI-FVETSAKNAININELFIEISR 164
            DL D R V  +  + +  +   I + ETSAK AIN+ + F  +++
Sbjct: 397 IDL-DNRVVTAKRGQGWCSTKGGIPYFETSAKEAINVEQAFQTVAK 263
>35581
          Length = 364

 Score = 68.6 bits (166), Expect = 1e-12,   Method: Compositional matrix adjust.
 Identities = 34/82 (41%), Positives = 45/82 (54%), Gaps = 1/82 (1%)
 Frame = +2

Query: 6   LKVCLLGDTGVGKSSIVWRFVEDSF-DPNINPTIGASFMTKTVQYQNELHKFLIWDTAGQ 64
            K  LLGD GVGK+ ++ R   D F D  +     AS +T        +    +WDTAGQ
Sbjct: 47  FKCVLLGDAGVGKTCLLNRLATDKFLDSPLTSLTTASLLTTVTLTSGVMASVDLWDTAGQ 226

Query: 65  ERFRALAPMYYRGSAAAIIVYD 86
           ER+R+L   YYR + A +IVYD
Sbjct: 227 ERYRSLTSSYYRDTKAVLIVYD 292
>13750
          Length = 503

 Score = 67.0 bits (162), Expect = 4e-12,   Method: Compositional matrix adjust.
 Identities = 35/110 (31%), Positives = 63/110 (57%), Gaps = 1/110 (0%)
 Frame = -2

Query: 55  KFLIWDTAGQERFRALAPMYYRGSAAAIIVYDITKEETFSTLKN-WVRELRQHGPPSIVV 113
           ++ +WDT G E +R+L   ++RG+  A++VYD+T E +F T    W + L ++ P + V+
Sbjct: 388 RYTLWDTGGAETYRSLWVSHFRGAQVALLVYDVTCEWSFLTATTVWRKALMKNIPEAQVI 209

Query: 114 AIAGNKCDLTDVREVMERDAKDYADSIHAIFVETSAKNAININELFIEIS 163
            + G+K DL + R +     + +A      F ETS+    N++ +F EI+
Sbjct: 208 FV-GSKTDLEENRVISTERGQAFATQCGYTFFETSSVTGKNVDAVFWEIA 62
>26536
          Length = 829

 Score = 67.0 bits (162), Expect = 4e-12,   Method: Compositional matrix adjust.
 Identities = 41/126 (32%), Positives = 63/126 (50%), Gaps = 6/126 (4%)
 Frame = +2

Query: 60  DTAGQERFRALAPMYYRGSAAAIIVYDITKEETFSTLKNWVREL-RQHGPPSIVVAIAGN 118
           DTAGQE + ++   Y R     I+VY +T   +F   +   R L R     SI   + GN
Sbjct: 146 DTAGQEEYSSMREHYTRSGDGFIVVYSVTDVTSFQEAEAVFRWLTRFQDETSIHAVLCGN 325

Query: 119 KCDLTDVREVMERDAKDYADSIHAIFVETSAKNAININELFIEISRRIPSTDANP----- 173
           K DLT  R+V   + +  AD +  ++ ETSAK   N+++++  + R IP +  +      
Sbjct: 326 KTDLTSDRKVTPEEGRKMADRLGMLYFETSAKTGDNVSQVYHGLLRSIPRSGTDYKIVML 505

Query: 174 ASGGKG 179
            SGG G
Sbjct: 506 GSGGVG 523

 Score = 38.5 bits (88), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 17/38 (44%), Positives = 25/38 (65%)
 Frame = +2

Query: 5   ELKVCLLGDTGVGKSSIVWRFVEDSFDPNINPTIGASF 42
           + K+ +LG  GVGKSS+  RF +D+F    +PTI  S+
Sbjct: 485 DYKIVMLGSGGVGKSSLTIRFTQDTFLDVYDPTIEDSY 598
>09204
          Length = 1051

 Score = 64.7 bits (156), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 38/102 (37%), Positives = 57/102 (55%), Gaps = 4/102 (3%)
 Frame = -3

Query: 66   RFRALAPMYYRGSAAAIIVYDITKEETFSTLKNWVRELRQHGPPSIVVAIAGNKCDLT-- 123
            R+ A++ +YYRG+ AAI+ +D+T + +F  ++ W+ ELRQH      + I G K DL   
Sbjct: 1049 RYEAMSRIYYRGAKAAILCFDLTDKSSFDRIRFWIGELRQH-EEECKLYICGTKFDLVHD 873

Query: 124  --DVREVMERDAKDYADSIHAIFVETSAKNAININELFIEIS 163
              + R V    AK  AD   A   ETS+    NI +LF +I+
Sbjct: 872  DPERRAVPRSVAKALADDCMAEIYETSSMTGDNIEKLFTKIA 747
>13745
          Length = 1045

 Score = 64.7 bits (156), Expect = 3e-11,   Method: Compositional matrix adjust.
 Identities = 38/106 (35%), Positives = 56/106 (52%), Gaps = 5/106 (4%)
 Frame = +2

Query: 64  QERFRALAPMYYRGSAAAIIVYDITKEETFSTLKNWVREL----RQHGPPSIVVAIAGNK 119
           QERF++L   +YRG+   ++VYD+T   +F  L +W  E         P      + GNK
Sbjct: 2   QERFQSLGVAFYRGADCCVLVYDVTAPNSFKNLDSWRDEFLIQASPRDPEHFPFVVLGNK 181

Query: 120 CDLTDVREVMERDAKDYADSIHAI-FVETSAKNAININELFIEISR 164
            DL D R+V  R A+ +  S + I + ETSAK  IN+   F  I++
Sbjct: 182 VDL-DNRQVSTRRAQQWCQSKNDIPYYETSAKEGINVEMAFQTIAK 316
>11728
          Length = 635

 Score = 62.0 bits (149), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 33/130 (25%), Positives = 68/130 (52%), Gaps = 1/130 (0%)
 Frame = -1

Query: 3   LRELKVCLLGDTGVGKSSIVWRFVEDSFDPNINPTIGASFMTKTVQYQNELHKFLIWDTA 62
           ++ +K  ++GD  VGK+ ++  +  ++F     PT+  ++ +  V   ++     +WDTA
Sbjct: 497 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNY-SANVMVDSKPINLGLWDTA 321

Query: 63  GQERFRALAPMYYRGSAAAIIVYDITKEETFSTLK-NWVRELRQHGPPSIVVAIAGNKCD 121
           GQE +  L P+ Y  +   +I + +    +F  +K  W  E+  H P + ++ + G K D
Sbjct: 320 GQEDYDRLRPLSYPQTDVFLICFSLISPASFENVKAKWYPEVSHHCPNTPII-LVGTKLD 144

Query: 122 LTDVREVMER 131
           L + +E +E+
Sbjct: 143 LREDKETIEK 114
>34359
          Length = 1042

 Score = 60.5 bits (145), Expect = 5e-10,   Method: Compositional matrix adjust.
 Identities = 39/120 (32%), Positives = 59/120 (49%)
 Frame = +3

Query: 5   ELKVCLLGDTGVGKSSIVWRFVEDSFDPNINPTIGASFMTKTVQYQNELHKFLIWDTAGQ 64
             K+ L+G      ++IV R V  S    +  T+G             L +F +WDTAGQ
Sbjct: 51  NFKLVLVGGRWEWANNIVKRHVTGS*KKYV-ATLGVEVHPLQFNTSRGLLRFNVWDTAGQ 227

Query: 65  ERFRALAPMYYRGSAAAIIVYDITKEETFSTLKNWVRELRQHGPPSIVVAIAGNKCDLTD 124
           E+F  L   YY     AII++D+T   T+  + NW R+L +    +I + + GNK D+ D
Sbjct: 228 EKFGGLRDGYYIQGTCAIIMFDVTSRVTYKNVPNWHRDLVRVC-ENIPIVLCGNKVDIKD 404
>14119
          Length = 602

 Score = 60.1 bits (144), Expect = 6e-10,   Method: Compositional matrix adjust.
 Identities = 29/76 (38%), Positives = 48/76 (63%), Gaps = 1/76 (1%)
 Frame = +1

Query: 92  TFSTLKNWVRELRQHGPPSIVVAIAGNKCDL-TDVREVMERDAKDYADSIHAIFVETSAK 150
           TF+    WV+ELRQ    S+++ +AGNK DL ++ R V   DA+ +A+    IF E SAK
Sbjct: 1   TFNRALAWVKELRQQNAGSVLIVLAGNKADLASEHRAVSADDARTFAEDNGLIFAEVSAK 180

Query: 151 NAININELFIEISRRI 166
             + ++E+F+ I+ ++
Sbjct: 181 TGMAVSEVFMTIAHKL 228
>19006
          Length = 568

 Score = 59.7 bits (143), Expect = 7e-10,   Method: Compositional matrix adjust.
 Identities = 31/117 (26%), Positives = 63/117 (53%), Gaps = 1/117 (0%)
 Frame = -2

Query: 7   KVCLLGDTGVGKSSIVWRFVEDSFDPNINPTIGASFMTKTVQYQNELHKFLIWDTAGQER 66
           K+ ++GD   GK+ ++  F +D F     PT+  +++   ++  ++  +  +WDTAGQE 
Sbjct: 432 KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVAD-IEVDSKQVELALWDTAGQED 256

Query: 67  FRALAPMYYRGSAAAIIVYDITKEETFSTL-KNWVRELRQHGPPSIVVAIAGNKCDL 122
           +  L P+ Y  +   ++ + I   ++   + + W  E+R H  P++ + + GNK DL
Sbjct: 255 YDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVR-HFCPNVPIILVGNKKDL 88
>27191
          Length = 443

 Score = 56.6 bits (135), Expect = 7e-09,   Method: Compositional matrix adjust.
 Identities = 27/102 (26%), Positives = 48/102 (47%)
 Frame = +1

Query: 18  KSSIVWRFVEDSFDPNINPTIGASFMTKTVQYQNELHKFLIWDTAGQERFRALAPMYYRG 77
           K+ ++  F E  F+    PT+G  +  K         +  +WD +G   +  +    Y G
Sbjct: 1   KTCLIKHFCESKFNQGYQPTVGVDYGFKIQTVNGVDMRVHMWDLSGSNEYLDVRNELYTG 180

Query: 78  SAAAIIVYDITKEETFSTLKNWVRELRQHGPPSIVVAIAGNK 119
           S A  IV+D++   +F  L +W+RE+ +    S +  I GN+
Sbjct: 181 SDAIFIVFDVSNTPSFEALDSWLREINRFATGSPLNVIVGNR 306
>00858
          Length = 1658

 Score = 55.5 bits (132), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 41/150 (27%), Positives = 68/150 (45%), Gaps = 1/150 (0%)
 Frame = -2

Query: 18   KSSIVWRFVEDSFDPNINPTIGASFMTKTVQYQNELHKFLIWDTAGQERFRALAPMYYRG 77
            KS++  +  ++ F    +PT   S   K V    E     I DTAGQE   A+     R 
Sbjct: 1552 KSALTIQLXQNHFVEEYDPTXEDS-XRKQVVIDGETCLLDILDTAGQEEXSAMRDQCMRT 1376

Query: 78   SAAAIIVYDITKEETFSTLKNWVREL-RQHGPPSIVVAIAGNKCDLTDVREVMERDAKDY 136
                + V+ +   ++F  +  +  ++ R      + + + GNK DL  +R V +R  K  
Sbjct: 1375 GEGFLCVFAVXNLKSFEDINQYREQIKRVKDADEVPMVLVGNKVDLP-IRNVEQRQGKHM 1199

Query: 137  ADSIHAIFVETSAKNAININELFIEISRRI 166
            A+  H  +VETSAK    +++ F  + R I
Sbjct: 1198 AELYHIPYVETSAKTRQGVDDAFYTLVREI 1109
>19656
          Length = 428

 Score = 55.5 bits (132), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 27/109 (24%), Positives = 54/109 (49%), Gaps = 1/109 (0%)
 Frame = +3

Query: 1   MALRELKVCLLGDTGVGKSSIVWRFVEDSFDPNINPTIGASFMTKTVQYQNELHKFLIWD 60
           MA++ +K  ++GD  VGK+ ++  +  ++F     PT+  ++ +  V          +WD
Sbjct: 99  MAMQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNY-SANVMVDGRPVNLGLWD 275

Query: 61  TAGQERFRALAPMYYRGSAAAIIVYDITKEETFSTLK-NWVRELRQHGP 108
           TAGQE +  L P+ Y  +   ++ + +    +F  ++  W  E+  H P
Sbjct: 276 TAGQEDYDRLRPLSYPQTDVFLLCFSVASPASFENIRAKWYPEVNHHCP 422
>00552
          Length = 455

 Score = 52.8 bits (125), Expect = 8e-08,   Method: Compositional matrix adjust.
 Identities = 27/49 (55%), Positives = 31/49 (63%)
 Frame = -1

Query: 4   RELKVCLLGDTGVGKSSIVWRFVEDSFDPNINPTIGASFMTKTVQYQNE 52
           R LKV LLGD GVGKSS++ RFV + FD     TIG  F+TK V    E
Sbjct: 449 RLLKVVLLGDGGVGKSSLMNRFVSNKFDAQSFHTIGVEFLTKDVVVDGE 303

 Score = 45.8 bits (107), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 16/49 (32%), Positives = 30/49 (61%)
 Frame = -3

Query: 58  IWDTAGQERFRALAPMYYRGSAAAIIVYDITKEETFSTLKNWVRELRQH 106
           IWDTAGQER+++L   +YRG+   ++ + +   ++  +L +W  E   +
Sbjct: 147 IWDTAGQERYKSLRTPFYRGTDCCLLTFSVDNLKSLQSLSDWYDEFVNY 1
>08153
          Length = 1703

 Score = 52.8 bits (125), Expect = 9e-08,   Method: Compositional matrix adjust.
 Identities = 34/120 (28%), Positives = 59/120 (49%), Gaps = 1/120 (0%)
 Frame = +1

Query: 4   RELKVCLLGDTGVGKSSIVWRFVEDSFDPNINPTIGASFMTKTVQYQNELHKFLIWDTAG 63
           +E+++ ++G    GK++I+++         I PTIG  F  +TV+Y+N    F +WD  G
Sbjct: 79  KEVRILMVGLDAAGKTTILYKLKLGEIVTTI-PTIG--FNVETVEYKN--ISFTVWDVGG 243

Query: 64  QERFRALAPMYYRGSAAAIIVYDITKEETFSTLK-NWVRELRQHGPPSIVVAIAGNKCDL 122
           Q++ R L   Y++ +   I V D    E  +  K    R L +      ++ +  NK DL
Sbjct: 244 QDKIRPLWRHYFQNTQGLIFVVDSNDRERINEAKEELARMLNEDDLRDAIILVFANKQDL 423
>25618
          Length = 475

 Score = 52.4 bits (124), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 25/67 (37%), Positives = 43/67 (64%), Gaps = 1/67 (1%)
 Frame = +3

Query: 101 RELRQHGPPSIVVAIAGNKCDL-TDVREVMERDAKDYADSIHAIFVETSAKNAININELF 159
           +ELRQ    S+++ +AGNK DL ++ R V   DA+ +A+    IF E SAK  + ++E+F
Sbjct: 48  KELRQQNAGSVLIVLAGNKADLASEHRAVSADDARTFAEDNGLIFAEVSAKTGMAVSEVF 227

Query: 160 IEISRRI 166
           + I+ ++
Sbjct: 228 MTIAHKL 248
>34597
          Length = 773

 Score = 52.4 bits (124), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 32/89 (35%), Positives = 48/89 (53%), Gaps = 4/89 (4%)
 Frame = -2

Query: 92  TFSTLKNWVRELRQHGPPSIVVAIAGNKCDLTDVREVMERDAKDYADSI---HAI-FVET 147
           +F  +  W+R + +H    +   I GNKCD+TD R V    +K+  ++I   H+I F+ET
Sbjct: 709 SFENIVKWLRNIDEHANEDVEKMILGNKCDMTDKRVV----SKERGEAIAREHSIRFMET 542

Query: 148 SAKNAININELFIEISRRIPSTDANPASG 176
           SAK+ INI   F E++  I    A   S 
Sbjct: 541 SAKSNINIERAFCELAEAILDKTAGRESA 455
>31291
          Length = 446

 Score = 51.2 bits (121), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 33/121 (27%), Positives = 54/121 (44%), Gaps = 14/121 (11%)
 Frame = -1

Query: 58  IWDTAGQERFRALAPMYYRGSAAAIIVYDITKEETFSTLK-NWVRELRQHGPPSIVVAIA 116
           +WDTAGQE +  L P+ Y  +   ++ + +  E +   +K  W  E+R H  P + + + 
Sbjct: 440 LWDTAGQEDYDRLRPLAYPNTDVFMLXFSLMSEASMKNVKVKWYPEIRHHD-PHVPIVLV 264

Query: 117 GNKCDLTDVREVMER------------DAKDYADSIHAI-FVETSAKNAININELFIEIS 163
           G K DL   +E + +               D A +I A  + E S+K   N+   F E  
Sbjct: 263 GTKLDLRQDKEAVRKLRSSRQDPVSSNQGNDLAKAIKAKRYFECSSKTQENLKTAFEETV 84

Query: 164 R 164
           R
Sbjct: 83  R 81
>09827
          Length = 1201

 Score = 50.8 bits (120), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 34/120 (28%), Positives = 59/120 (49%), Gaps = 1/120 (0%)
 Frame = -3

Query: 4    RELKVCLLGDTGVGKSSIVWRFVEDSFDPNINPTIGASFMTKTVQYQNELHKFLIWDTAG 63
            +++++ ++G    GK++I+++         I PTIG  F  +TV+Y+N    F +WD  G
Sbjct: 1118 KDMRILMVGLDAAGKTTILYKLKLGEIVTTI-PTIG--FNVETVEYKN--ISFTVWDVGG 954

Query: 64   QERFRALAPMYYRGSAAAIIVYDIT-KEETFSTLKNWVRELRQHGPPSIVVAIAGNKCDL 122
            Q++ R L   Y++ +   I V D   KE      +   R L +      V+ +  NK DL
Sbjct: 953  QDKIRPLWRHYFQNTQGLIFVVDSNDKERVQEAREELTRMLNEDELRDAVLLVFANKQDL 774
>19046
          Length = 445

 Score = 49.7 bits (117), Expect = 8e-07,   Method: Compositional matrix adjust.
 Identities = 31/105 (29%), Positives = 53/105 (50%), Gaps = 2/105 (1%)
 Frame = -2

Query: 64  QERFRALAPMYYRGSAAAIIVYDITKEETFSTLKNWVRE-LRQHGPPSIVVAIAGNKCDL 122
           QE F A+   Y R     ++V+ +T   +F  + N+  + LR     S  + +  NK DL
Sbjct: 444 QEEFSAMREQYMRKGDGFLLVFSVTDFRSFENMANFHTQILRVKDRDSYPMILCANKVDL 265

Query: 123 TDVREVMERDAKDYADSIHAIFVETSAKN-AININELFIEISRRI 166
              R+V E   +D A  +   ++ETSAK+  +N++  F ++ R I
Sbjct: 264 VHQRKVSEEQVRDLATRLRIPYIETSAKDPPLNVDLAFHQVVRVI 130
>24619
          Length = 509

 Score = 47.4 bits (111), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 29/105 (27%), Positives = 53/105 (50%), Gaps = 2/105 (1%)
 Frame = -2

Query: 64  QERFRALAPMYYRGSAAAIIVYDITKEETFSTLKNWVRE-LRQHGPPSIVVAIAGNKCDL 122
           QE F A+   Y R     ++V+ +   ++F  + N+  + LR     +  + +  NK DL
Sbjct: 508 QEEFSAMREQYMRKGDGFLLVFSVIDYQSFENMVNFHTQILRVKDRDTYPMILCANKVDL 329

Query: 123 TDVREVMERDAKDYADSIHAIFVETSAKN-AININELFIEISRRI 166
              R+V E   +D A  +   ++ETSAK+  +N++  F ++ R I
Sbjct: 328 VHQRKVSEEQVRDLATRLRIPYIETSAKDPPLNVDLAFHQVVRVI 194
>17872
          Length = 700

 Score = 46.6 bits (109), Expect = 7e-06,   Method: Compositional matrix adjust.
 Identities = 32/109 (29%), Positives = 54/109 (49%), Gaps = 13/109 (11%)
 Frame = -1

Query: 64  QERFRALAPMYYRGSAAAIIVYDITKEETF-STLKNWVRELRQHGPPSIVVAIAGNKCDL 122
           Q+ F +L P+ Y  +   ++ + +    +F + ++ WV ELR H P + +V + G + DL
Sbjct: 700 QDDFDSLRPLCYPETNVFLLCFSVVSPTSFHNVMEKWVPELRYHCPGAPLV-VVGTQSDL 524

Query: 123 -TDV-----------REVMERDAKDYADSIHAIFVETSAKNAININELF 159
             DV           + V E +A   AD + A +VE SA    N+ E+F
Sbjct: 523 RNDVKVLIELAKYKEKPVSEEEAVKMADQLGAQYVECSALTQKNLKEVF 377
>18208
          Length = 458

 Score = 43.1 bits (100), Expect = 7e-05,   Method: Compositional matrix adjust.
 Identities = 29/84 (34%), Positives = 43/84 (51%), Gaps = 1/84 (1%)
 Frame = -1

Query: 4   RELKVCLLGDTGVGKSSIVWRFVEDSFDP-NINPTIGASFMTKTVQYQNELHKFLIWDTA 62
           REL++ LLG    GK++++ +   +  DP +I PT G  F  K+VQ +    K  +WD  
Sbjct: 305 RELRILLLGLDNAGKTTLLKQLASE--DPSHITPTQG--FNIKSVQSKG--FKLNVWDIG 144

Query: 63  GQERFRALAPMYYRGSAAAIIVYD 86
           GQ R R     Y+  +   I V D
Sbjct: 143 GQRRIRPYWKNYFENTDLLIYVID 72
>33605
          Length = 888

 Score = 43.1 bits (100), Expect = 7e-05,   Method: Compositional matrix adjust.
 Identities = 24/83 (28%), Positives = 46/83 (55%)
 Frame = +1

Query: 4   RELKVCLLGDTGVGKSSIVWRFVEDSFDPNINPTIGASFMTKTVQYQNELHKFLIWDTAG 63
           +E+++ +LG    GK++I+ +F  +  D  I+PT+G  F  KT++++    K  +WD  G
Sbjct: 493 KEVRLLMLGLDNAGKTTILKKFNGEDIDT-ISPTLG--FNIKTLEHRG--FKLNVWDVGG 657

Query: 64  QERFRALAPMYYRGSAAAIIVYD 86
           Q+  R+    Y+  +   + V D
Sbjct: 658 QQSLRSYWRNYFESTDGLVWVVD 726
>14775
          Length = 380

 Score = 42.0 bits (97), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 15/36 (41%), Positives = 26/36 (72%)
 Frame = -2

Query: 55  KFLIWDTAGQERFRALAPMYYRGSAAAIIVYDITKE 90
           ++ +WDT G E +R+L   ++RG+  A++VYD+T E
Sbjct: 265 RYTLWDTGGAETYRSLWVSHFRGAQVALLVYDVTCE 158
>18509
          Length = 625

 Score = 37.7 bits (86), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 20/54 (37%), Positives = 30/54 (55%)
 Frame = -3

Query: 113 VAIAGNKCDLTDVREVMERDAKDYADSIHAIFVETSAKNAININELFIEISRRI 166
           + + GNK DL  +R V +R  K  A+  H  +VETSAK    +++ F  + R I
Sbjct: 521 MVLVGNKVDLP-IRNVEQRQGKHMAELYHIPYVETSAKTRQGVDDAFYTLVREI 363
>10862
          Length = 2896

 Score = 37.0 bits (84), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 22/76 (28%), Positives = 33/76 (43%), Gaps = 6/76 (7%)
 Frame = -3

Query: 55   KFLIWDTAGQERFRALAPMYYRGSAAAIIVYDITKEETFSTLKNWV------RELRQHGP 108
            +F +WD  GQ++ R L   YY G+   I V D    +     +  +      RE+R    
Sbjct: 2483 QFNVWDVGGQDKIRPLWRHYYTGTQGLIFVVDCADRDRIDEARQELHRIINDREMR---- 2316

Query: 109  PSIVVAIAGNKCDLTD 124
               ++ I  NK DL D
Sbjct: 2315 -DAIILIFANKQDLPD 2271
>10708
          Length = 2775

 Score = 32.3 bits (72), Expect = 0.13,   Method: Compositional matrix adjust.
 Identities = 15/55 (27%), Positives = 29/55 (52%)
 Frame = -2

Query: 55   KFLIWDTAGQERFRALAPMYYRGSAAAIIVYDITKEETFSTLKNWVRELRQHGPP 109
            +  +WDTAGQE +  L P+ Y  +   ++ + I   ++  +L+N   ++   G P
Sbjct: 2720 ELALWDTAGQEDYDRLRPLSYPDTDVILMCFSI---DSPDSLENIPEKVDSRGAP 2565
>25697
          Length = 470

 Score = 29.3 bits (64), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 18/52 (34%), Positives = 26/52 (50%)
 Frame = +1

Query: 87  ITKEETFSTLKNWVRELRQHGPPSIVVAIAGNKCDLTDVREVMERDAKDYAD 138
           IT   T STL  ++ EL++HG   +V       CD T  +E +E +  D  D
Sbjct: 10  ITDRPTDSTLDKFIEELQKHGARHVVRV-----CDPTYSKEKLETEGIDVMD 150
>15478
          Length = 1282

 Score = 28.1 bits (61), Expect = 2.3,   Method: Compositional matrix adjust.
 Identities = 24/90 (26%), Positives = 39/90 (43%), Gaps = 13/90 (14%)
 Frame = +1

Query: 115 IAGNKCDL-------TDVREVMERDAKDYADS---IHAIFVETSAKN---AININELFIE 161
           +AG + DL        +V++  E+DA DYA +    HA+    SA +   A  +NE  + 
Sbjct: 880 VAGRQKDLEKMAQRMQEVKQASEKDAADYAAAQKHFHAVSSGLSANDDGEAATLNEQLLA 1059

Query: 162 ISRRIPSTDANPASGGKGFKLRRQPSEPKR 191
               I + + N        KL+    E K+
Sbjct: 1060AKNEISTAETNTKQA--QMKLKHAEQEXKK 1143
>07633
          Length = 995

 Score = 27.3 bits (59), Expect = 4.0,   Method: Compositional matrix adjust.
 Identities = 12/17 (70%), Positives = 14/17 (82%)
 Frame = -3

Query: 5   ELKVCLLGDTGVGKSSI 21
           EL+V LLG TG GKSS+
Sbjct: 915 ELRVVLLGKTGSGKSSL 865
>22347
          Length = 732

 Score = 27.3 bits (59), Expect = 4.2,   Method: Compositional matrix adjust.
 Identities = 15/49 (30%), Positives = 26/49 (53%)
 Frame = -1

Query: 145 VETSAKNAININELFIEISRRIPSTDANPASGGKGFKLRRQPSEPKRSC 193
           + ++ K   N+ + F E+++R  + + N    G  F L  + SEPK SC
Sbjct: 150 IYSAVKRQYNLRKKF-ELAQRYTTHEGNRNRLGSSFSLILKISEPKESC 7
>06884
          Length = 897

 Score = 26.9 bits (58), Expect = 5.5,   Method: Compositional matrix adjust.
 Identities = 12/39 (30%), Positives = 25/39 (64%)
 Frame = -2

Query: 13  DTGVGKSSIVWRFVEDSFDPNINPTIGASFMTKTVQYQN 51
           +TG+ K +I+W+ ++   D NI+PT+    + ++ Q+ N
Sbjct: 470 NTGLCKLTIIWQDIQCLTDCNISPTLM---IYRSFQFYN 363
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|161016799|ref|NP_038499.2| annexin A4 [Mus musculus]
         (319 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

32521                                                                 245   2e-65
06659                                                                 157   5e-39
36934                                                                 137   5e-33
22178                                                                 118   3e-27
17882                                                                  59   6e-19
13827                                                                  73   2e-15
12136                                                                  69   2e-12
29756                                                                  62   3e-10
>32521
          Length = 1241

 Score =  245 bits (626), Expect = 2e-65,   Method: Compositional matrix adjust.
 Identities = 121/269 (44%), Positives = 179/269 (66%)
 Frame = +2

Query: 48  QRQEIRSAYKSTIGRDLIEDLKSELSSNFEQVILGLMTPTVLYDVQELRRAMKGAGTDEG 107
           QR+EI   YK+  G+DL ++L  ELS NF+ + + ++     +D +++ +A+KG GTDE 
Sbjct: 5   QRREINLTYKTMFGKDLGKELSGELSGNFKTLCVEMLLGPAEFDAKQINKAVKGLGTDER 184

Query: 108 CLIEILASRTPEEIRRINQTYQQQYGRSLEEDICSDTSFMFQRVLVSLSAAGRDEGNYLD 167
            LIEI+ +RT  ++  + + Y+  Y + +E DI  DTS  F+R+L+    A R EG   D
Sbjct: 185 ALIEIICTRTNAQLTAMKEAYKTMYQKDVETDIEGDTSGPFKRLLIGCLQANRPEGQEFD 364

Query: 168 DALMKQDAQELYEAGEKRWGTDEVKFLSILCSRNRNHLLHVFDEYKRISQKDIEQSIKSE 227
               KQDAQ L EAGEK+WGTDE +F  ++ SR+   L   F EY +++ KDIE SI SE
Sbjct: 365 RNKAKQDAQALLEAGEKKWGTDESRFNVVIVSRSFPQLRATFQEYAKLANKDIEDSISSE 544

Query: 228 TSGSFEDALLAIVKCMRSKPSYFAERLYKSMKGLGTDDNTLIRVMVSRAEIDMLDIRASF 287
            SG  ++ +L +V+ +RSK ++FA  L+++MKGLGTDD+TL+RV+ SR E+DM+ I+  F
Sbjct: 545 MSGDXKNGMLTVVRVIRSKATHFATELHRAMKGLGTDDDTLVRVVASRCEVDMVQIKEEF 724

Query: 288 KRLYGKSLYSFIKGDTSGDYRKVLLVLCG 316
           +R + ++LYSFI  DTSGDYR +L  L G
Sbjct: 725 QRNFKQTLYSFIVDDTSGDYRLMLCNLIG 811

 Score = 77.4 bits (189), Expect = 8e-15,   Method: Compositional matrix adjust.
 Identities = 61/234 (26%), Positives = 115/234 (49%), Gaps = 12/234 (5%)
 Frame = +2

Query: 19  DAQTLRKAMKGLGTDEDAIIGILAYRNTAQRQEIRSAYKSTIGRDLIEDLKSELSSNFEQ 78
           DA+ + KA+KGLGTDE A+I I+  R  AQ   ++ AYK+   +D+  D++ + S  F++
Sbjct: 134 DAKQINKAVKGLGTDERALIEIICTRTNAQLTAMKEAYKTMYQKDVETDIEGDTSGPFKR 313

Query: 79  VILGLMTPT-----------VLYDVQELRRA-MKGAGTDEGCLIEILASRTPEEIRRINQ 126
           +++G +                 D Q L  A  K  GTDE     ++ SR+  ++R   Q
Sbjct: 314 LLIGCLQANRPEGQEFDRNKAKQDAQALLEAGEKKWGTDESRFNVVIVSRSFPQLRATFQ 493

Query: 127 TYQQQYGRSLEEDICSDTSFMFQRVLVSLSAAGRDEGNYLDDALMKQDAQELYEAGEKRW 186
            Y +   + +E+ I S+ S   +  ++++    R +  +         A EL+ A  K  
Sbjct: 494 EYAKLANKDIEDSISSEMSGDXKNGMLTVVRVIRSKATHF--------ATELHRA-MKGL 646

Query: 187 GTDEVKFLSILCSRNRNHLLHVFDEYKRISQKDIEQSIKSETSGSFEDALLAIV 240
           GTD+   + ++ SR    ++ + +E++R  ++ +   I  +TSG +   L  ++
Sbjct: 647 GTDDDTLVRVVASRCEVDMVQIKEEFQRNFKQTLYSFIVDDTSGDYRLMLCNLI 808

 Score = 36.6 bits (83), Expect = 0.013,   Method: Compositional matrix adjust.
 Identities = 19/69 (27%), Positives = 37/69 (53%)
 Frame = +2

Query: 16  ATEDAQTLRKAMKGLGTDEDAIIGILAYRNTAQRQEIRSAYKSTIGRDLIEDLKSELSSN 75
           AT  A  L +AMKGLGTD+D ++ ++A R      +I+  ++    + L   +  + S +
Sbjct: 602 ATHFATELHRAMKGLGTDDDTLVRVVASRCEVDMVQIKEEFQRNFKQTLYSFIVDDTSGD 781

Query: 76  FEQVILGLM 84
           +  ++  L+
Sbjct: 782 YRLMLCNLI 808
>06659
          Length = 776

 Score =  157 bits (397), Expect = 5e-39,   Method: Compositional matrix adjust.
 Identities = 91/225 (40%), Positives = 143/225 (63%), Gaps = 5/225 (2%)
 Frame = -3

Query: 95  LRRAMKGAGTDEGCLIEILASRTPEEIRRINQTYQQQYGRSLEEDICSDTSFMFQRVLVS 154
           L  A+ GAGTDE CLI+I+ +R  +E++ I + Y++++   LEED+ +DT   F+R+++S
Sbjct: 774 LHDAISGAGTDEKCLIDIMCTRDNDEMKEIKEKYKEEFESELEEDLQADTGGYFRRLMIS 595

Query: 155 LSAAGRDEGNYL----DDALMKQDAQELYEAGEKRWGTDEVKFLSILCSRNRNHLLHVFD 210
           L   GRD  N+     D A+  +DAQ+  EAGE  WGT+E    +ILC  +   L    +
Sbjct: 594 LCVGGRDYDNWWXANEDKAV--EDAQKFLEAGENAWGTEEADMNAILCRTSPAQLCKTIE 421

Query: 211 EYKRISQ-KDIEQSIKSETSGSFEDALLAIVKCMRSKPSYFAERLYKSMKGLGTDDNTLI 269
           +Y+ +++ K +E+SI+SE S    D  LAIV+  RS P YFA RL     GLGT DN LI
Sbjct: 420 KYEELTEGKTMEESIRSECSDDLXDGYLAIVESARSMPRYFARRLNDCFSGLGTSDNDLI 241

Query: 270 RVMVSRAEIDMLDIRASFKRLYGKSLYSFIKGDTSGDYRKVLLVL 314
           R++VSR+E+D+  I+ +++ +Y K L   ++ +  GDY+++LL +
Sbjct: 240 RIIVSRSEVDLEAIKQAYEEMYEKPLTEAVESECGGDYKRLLLAI 106

 Score = 46.6 bits (109), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 56/234 (23%), Positives = 109/234 (46%), Gaps = 15/234 (6%)
 Frame = -3

Query: 23  LRKAMKGLGTDEDAIIGILAYRNTAQRQEIRSAYKSTIGRDLIEDLKSELSSNFEQVILG 82
           L  A+ G GTDE  +I I+  R+  + +EI+  YK     +L EDL+++    F ++++ 
Sbjct: 774 LHDAISGAGTDEKCLIDIMCTRDNDEMKEIKEKYKEEFESELEEDLQADTGGYFRRLMIS 595

Query: 83  LMT-------------PTVLYDVQELRRAMKGA-GTDEGCLIEILASRTPEEIRRINQTY 128
           L                  + D Q+   A + A GT+E  +  IL   +P ++ +  + Y
Sbjct: 594 LCVGGRDYDNWWXANEDKAVEDAQKFLEAGENAWGTEEADMNAILCRTSPAQLCKTIEKY 415

Query: 129 QQ-QYGRSLEEDICSDTSFMFQRVLVSLSAAGRDEGNYLDDALMKQDAQELYEAGEKRWG 187
           ++   G+++EE I S+ S       +++  + R    Y         A+ L +      G
Sbjct: 414 EELTEGKTMEESIRSECSDDLXDGYLAIVESARSMPRYF--------ARRLNDCFSGL-G 262

Query: 188 TDEVKFLSILCSRNRNHLLHVFDEYKRISQKDIEQSIKSETSGSFEDALLAIVK 241
           T +   + I+ SR+   L  +   Y+ + +K + ++++SE  G ++  LLAI+ 
Sbjct: 261 TSDNDLIRIIVSRSEVDLEAIKQAYEEMYEKPLTEAVESECGGDYKRLLLAILN 100
>36934
          Length = 667

 Score =  137 bits (346), Expect = 5e-33,   Method: Compositional matrix adjust.
 Identities = 78/204 (38%), Positives = 120/204 (58%), Gaps = 1/204 (0%)
 Frame = +3

Query: 13  GFNATEDAQTLRKAMKGLG-TDEDAIIGILAYRNTAQRQEIRSAYKSTIGRDLIEDLKSE 71
           G  A EDA+ L KAM G+G T ED ++ I+  R+ +QRQ ++  YK    RDL E L+SE
Sbjct: 9   GRKAAEDAERLHKAMSGMGVTHEDTVLEIIIKRSNSQRQTLKKKYKEMYKRDLAEHLQSE 188

Query: 72  LSSNFEQVILGLMTPTVLYDVQELRRAMKGAGTDEGCLIEILASRTPEEIRRINQTYQQQ 131
           L+ +FE++ILGL+ P V YD   L +A+ G GT+E  LI IL +  P+E+  + + Y++ 
Sbjct: 189 LTGDFEELILGLLMPPVEYDAFCLNKAVDGLGTNEDVLIGILCTANPKELSSVKEVYKKT 368

Query: 132 YGRSLEEDICSDTSFMFQRVLVSLSAAGRDEGNYLDDALMKQDAQELYEAGEKRWGTDEV 191
           YG  L+  I  DTS  F+ +L++LS   RD+   +++   KQDAQ+L    + + G    
Sbjct: 369 YGEDLDSAIKGDTSGGFEDLLLALSRGERDQSKSVNEKEAKQDAQKLCPDKK*KTGHG** 548

Query: 192 KFLSILCSRNRNHLLHVFDEYKRI 215
            F  I    N+  +   F EY+++
Sbjct: 549 NFQYIDDKENKQQMKATFVEYEKL 620

 Score = 74.3 bits (181), Expect = 5e-14,   Method: Compositional matrix adjust.
 Identities = 44/146 (30%), Positives = 83/146 (56%)
 Frame = +3

Query: 173 QDAQELYEAGEKRWGTDEVKFLSILCSRNRNHLLHVFDEYKRISQKDIEQSIKSETSGSF 232
           +DA+ L++A      T E   L I+  R+ +    +  +YK + ++D+ + ++SE +G F
Sbjct: 24  EDAERLHKAMSGMGVTHEDTVLEIIIKRSNSQRQTLKKKYKEMYKRDLAEHLQSELTGDF 203

Query: 233 EDALLAIVKCMRSKPSYFAERLYKSMKGLGTDDNTLIRVMVSRAEIDMLDIRASFKRLYG 292
           E+ +L +   +     Y A  L K++ GLGT+++ LI ++ +    ++  ++  +K+ YG
Sbjct: 204 EELILGL---LMPPVEYDAFCLNKAVDGLGTNEDVLIGILCTANPKELSSVKEVYKKTYG 374

Query: 293 KSLYSFIKGDTSGDYRKVLLVLCGGD 318
           + L S IKGDTSG +  +LL L  G+
Sbjct: 375 EDLDSAIKGDTSGGFEDLLLALSRGE 452

 Score = 66.6 bits (161), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 48/164 (29%), Positives = 85/164 (51%), Gaps = 1/164 (0%)
 Frame = +3

Query: 91  DVQELRRAMKGAG-TDEGCLIEILASRTPEEIRRINQTYQQQYGRSLEEDICSDTSFMFQ 149
           D + L +AM G G T E  ++EI+  R+  + + + + Y++ Y R L E + S+ +  F+
Sbjct: 27  DAERLHKAMSGMGVTHEDTVLEIIIKRSNSQRQTLKKKYKEMYKRDLAEHLQSELTGDFE 206

Query: 150 RVLVSLSAAGRDEGNYLDDALMKQDAQELYEAGEKRWGTDEVKFLSILCSRNRNHLLHVF 209
            +++ L               ++ DA  L +A +   GT+E   + ILC+ N   L  V 
Sbjct: 207 ELILGLLMPP-----------VEYDAFCLNKAVDG-LGTNEDVLIGILCTANPKELSSVK 350

Query: 210 DEYKRISQKDIEQSIKSETSGSFEDALLAIVKCMRSKPSYFAER 253
           + YK+   +D++ +IK +TSG FED LLA+ +  R +     E+
Sbjct: 351 EVYKKTYGEDLDSAIKGDTSGGFEDLLLALSRGERDQSKSVNEK 482
>22178
          Length = 655

 Score =  118 bits (296), Expect = 3e-27,   Method: Compositional matrix adjust.
 Identities = 67/156 (42%), Positives = 97/156 (62%), Gaps = 5/156 (3%)
 Frame = +1

Query: 166 LDDALMKQDAQELYEAG---EKRWGTDEVKFLSIL--CSRNRNHLLHVFDEYKRISQKDI 220
           +D  +  Q+A ELY+AG   ++R G  +V+  S+         H   V    ++  +   
Sbjct: 1   VDPTIAMQEAHELYKAG*KGKRRDGRGDVQPHSVPEELRATAGHF*RVQANLRQGHRGRH 180

Query: 221 EQSIKSETSGSFEDALLAIVKCMRSKPSYFAERLYKSMKGLGTDDNTLIRVMVSRAEIDM 280
           ++  + +  G      LAIV+  R+ P+YFAERLYKSMKG GT+D  LIR +VSR+E D+
Sbjct: 181 QE*DEWQLGGGL---FLAIVRVARNTPAYFAERLYKSMKGAGTNDKALIRAIVSRSENDL 351

Query: 281 LDIRASFKRLYGKSLYSFIKGDTSGDYRKVLLVLCG 316
             I+  F+R+YGK+L S+IKGDTSGDY+K+LL LCG
Sbjct: 352 GFIKQEFQRMYGKTLASYIKGDTSGDYKKILLALCG 459

 Score = 52.8 bits (125), Expect(2) = 1e-12,   Method: Compositional matrix adjust.
 Identities = 26/71 (36%), Positives = 45/71 (63%)
 Frame = +1

Query: 85  TPTVLYDVQELRRAMKGAGTDEGCLIEILASRTPEEIRRINQTYQQQYGRSLEEDICSDT 144
           TP   Y  + L ++MKGAGT++  LI  + SR+  ++  I Q +Q+ YG++L   I  DT
Sbjct: 247 TPA--YFAERLYKSMKGAGTNDKALIRAIVSRSENDLGFIKQEFQRMYGKTLASYIKGDT 420

Query: 145 SFMFQRVLVSL 155
           S  ++++L++L
Sbjct: 421 SGDYKKILLAL 453

 Score = 37.7 bits (86), Expect(2) = 1e-12,   Method: Compositional matrix adjust.
 Identities = 19/48 (39%), Positives = 28/48 (58%)
 Frame = +2

Query: 30  LGTDEDAIIGILAYRNTAQRQEIRSAYKSTIGRDLIEDLKSELSSNFE 77
           +GTDE+    IL  RN  Q +    AY+   G+D+ + +KSE+S N E
Sbjct: 65  VGTDEETFNRILCLRNYGQLRATFDAYRQISGKDIEDAIKSEMSGNLE 208
>17882
          Length = 489

 Score = 59.3 bits (142), Expect(2) = 6e-19,   Method: Compositional matrix adjust.
 Identities = 28/56 (50%), Positives = 42/56 (75%)
 Frame = -1

Query: 261 LGTDDNTLIRVMVSRAEIDMLDIRASFKRLYGKSLYSFIKGDTSGDYRKVLLVLCG 316
           LGT+D+ LIR++VSR+EID+ DI+  +   Y K+L S +  DTSGDY+++LL + G
Sbjct: 354 LGTNDSRLIRIIVSRSEIDLQDIKDVYLSKYKKTLESAVASDTSGDYKRLLLAIVG 187

 Score = 52.0 bits (123), Expect(2) = 6e-19,   Method: Compositional matrix adjust.
 Identities = 23/46 (50%), Positives = 32/46 (69%)
 Frame = -2

Query: 218 KDIEQSIKSETSGSFEDALLAIVKCMRSKPSYFAERLYKSMKGLGT 263
           KD+  SI SE SG FE  L AIV+CM+++P YFA++L+  +K L  
Sbjct: 482 KDLLSSISSEMSGDFETGLRAIVRCMKNRPEYFADKLHDCIKFLAP 345

 Score = 35.8 bits (81), Expect = 0.021,   Method: Compositional matrix adjust.
 Identities = 19/54 (35%), Positives = 33/54 (61%)
 Frame = -1

Query: 187 GTDEVKFLSILCSRNRNHLLHVFDEYKRISQKDIEQSIKSETSGSFEDALLAIV 240
           GT++ + + I+ SR+   L  + D Y    +K +E ++ S+TSG ++  LLAIV
Sbjct: 351 GTNDSRLIRIIVSRSEIDLQDIKDVYLSKYKKTLESAVASDTSGDYKRLLLAIV 190
>13827
          Length = 483

 Score = 73.2 bits (178), Expect(2) = 2e-15,   Method: Compositional matrix adjust.
 Identities = 31/59 (52%), Positives = 46/59 (77%)
 Frame = -1

Query: 259 KGLGTDDNTLIRVMVSRAEIDMLDIRASFKRLYGKSLYSFIKGDTSGDYRKVLLVLCGG 317
           +G+GTDD TLIRV+V+R E+DM  I+  F+  YG++L +F++ D SGDYR+++L L GG
Sbjct: 444 RGMGTDDRTLIRVVVTRCEVDMKQIKQEFQNRYGQALEAFVRDDISGDYRRLMLALVGG 268

 Score = 26.2 bits (56), Expect(2) = 2e-15,   Method: Compositional matrix adjust.
 Identities = 11/15 (73%), Positives = 12/15 (80%)
 Frame = -3

Query: 248 SYFAERLYKSMKGLG 262
            YFA+RLY SMKG G
Sbjct: 478 GYFADRLYHSMKGDG 434

 Score = 42.4 bits (98), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 18/56 (32%), Positives = 38/56 (67%)
 Frame = -1

Query: 100 KGAGTDEGCLIEILASRTPEEIRRINQTYQQQYGRSLEEDICSDTSFMFQRVLVSL 155
           +G GTD+  LI ++ +R   ++++I Q +Q +YG++LE  +  D S  ++R++++L
Sbjct: 444 RGMGTDDRTLIRVVVTRCEVDMKQIKQEFQNRYGQALEAFVRDDISGDYRRLMLAL 277

 Score = 30.4 bits (67), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 12/57 (21%), Positives = 35/57 (61%)
 Frame = -1

Query: 28  KGLGTDEDAIIGILAYRNTAQRQEIRSAYKSTIGRDLIEDLKSELSSNFEQVILGLM 84
           +G+GTD+  +I ++  R     ++I+  +++  G+ L   ++ ++S ++ +++L L+
Sbjct: 444 RGMGTDDRTLIRVVVTRCEVDMKQIKQEFQNRYGQALEAFVRDDISGDYRRLMLALV 274
>12136
          Length = 445

 Score = 68.9 bits (167), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 39/106 (36%), Positives = 63/106 (59%), Gaps = 7/106 (6%)
 Frame = +3

Query: 64  LIEDLKSELSSNFEQVILGLMTPTVLYDVQELRRAMKGAGTDEGCLIEILASRTPEEIRR 123
           LIE++K ELS +++++++ L      YD   ++ A+ G GTDE  L+EIL +RT  +I+ 
Sbjct: 3   LIEEIKGELSGDYKELVMALFVAPAEYDAWCIKEAIYGPGTDEMALMEILMTRTNAQIKE 182

Query: 124 INQTYQ-----QQYGRS--LEEDICSDTSFMFQRVLVSLSAAGRDE 162
           +   Y        +GR+  +E+DI  D S  F+R+L+S S  GR E
Sbjct: 183 LRSIYPSVLNDHYHGRTPKIEQDIEDDCSGDFKRLLISASQGGRFE 320
>29756
          Length = 496

 Score = 62.0 bits (149), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 35/77 (45%), Positives = 43/77 (55%), Gaps = 1/77 (1%)
 Frame = +3

Query: 9   KAASGFNATEDAQTLRKAMKGLGTDEDAIIGILAYRNTAQRQEIRSAYKSTIGRDLIEDL 68
           K    FNA ED Q LRKAMKG GTDE AII IL YR + QRQ ++  YK+   +      
Sbjct: 249 KPYPRFNAEEDVQKLRKAMKGFGTDEKAIIDILGYRTSDQRQNLKLMYKNLFWKRFGAGF 428

Query: 69  -KSELSSNFEQVILGLM 84
            +   +  FE  +L LM
Sbjct: 429 *RVN*AGAFEDAMLALM 479

 Score = 43.1 bits (100), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 19/44 (43%), Positives = 30/44 (68%)
 Frame = +3

Query: 91  DVQELRRAMKGAGTDEGCLIEILASRTPEEIRRINQTYQQQYGR 134
           DVQ+LR+AMKG GTDE  +I+IL  RT ++ + +   Y+  + +
Sbjct: 279 DVQKLRKAMKGFGTDEKAIIDILGYRTSDQRQNLKLMYKNLFWK 410

 Score = 30.0 bits (66), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 16/53 (30%), Positives = 28/53 (52%), Gaps = 4/53 (7%)
 Frame = +3

Query: 247 PSYFAE----RLYKSMKGLGTDDNTLIRVMVSRAEIDMLDIRASFKRLYGKSL 295
           P + AE    +L K+MKG GTD+  +I ++  R      +++  +K L+ K  
Sbjct: 258 PRFNAEEDVQKLRKAMKGFGTDEKAIIDILGYRTSDQRQNLKLMYKNLFWKRF 416

 Score = 29.3 bits (64), Expect = 2.1,   Method: Compositional matrix adjust.
 Identities = 22/74 (29%), Positives = 40/74 (54%), Gaps = 1/74 (1%)
 Frame = +3

Query: 173 QDAQELYEAGEKRWGTDEVKFLSILCSRNRNHLLHVFDEYKRISQKDIEQSI-KSETSGS 231
           +D Q+L +A  K +GTDE   + IL  R  +   ++   YK +  K       +   +G+
Sbjct: 276 EDVQKLRKA-MKGFGTDEKAIIDILGYRTSDQRQNLKLMYKNLFWKRFGAGF*RVN*AGA 452

Query: 232 FEDALLAIVKCMRS 245
           FEDA+LA++  +++
Sbjct: 453 FEDAMLALMYNLKN 494
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|16418469|ref|NP_443205.1| striatin, calmodulin
binding protein 3 [Mus musculus]
         (796 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

04732                                                                 246   2e-65
09899                                                                 218   6e-57
21105                                                                 207   1e-53
30256                                                                  60   4e-09
17598                                                                  56   6e-08
01598                                                                  55   1e-07
19949                                                                  54   2e-07
02147                                                                  54   3e-07
12806                                                                  53   4e-07
01327                                                                  52   9e-07
03156                                                                  50   4e-06
00561                                                                  50   5e-06
03395                                                                  48   1e-05
13278                                                                  48   2e-05
13335                                                                  46   6e-05
19140                                                                  45   1e-04
20662                                                                  45   1e-04
17602                                                                  45   1e-04
00825                                                                  44   2e-04
19498                                                                  44   2e-04
21763                                                                  44   3e-04
37180                                                                  44   3e-04
11915                                                                  44   4e-04
02948                                                                  43   4e-04
26939                                                                  43   5e-04
30176                                                                  42   0.001
15118                                                                  42   0.001
15780                                                                  42   0.001
27465                                                                  42   0.001
21921                                                                  40   0.003
01249                                                                  40   0.003
12960                                                                  40   0.004
18981                                                                  40   0.005
15337                                                                  39   0.006
15972                                                                  39   0.009
11493                                                                  37   0.035
38039                                                                  37   0.037
02090                                                                  37   0.042
39204                                                                  37   0.045
07665                                                                  36   0.051
19863                                                                  36   0.057
31384                                                                  36   0.059
03387                                                                  36   0.064
27806                                                                  36   0.065
13890                                                                  35   0.088
12574                                                                  35   0.10 
01768                                                                  34   0.24 
04524                                                                  34   0.27 
16199                                                                  33   0.39 
26107                                                                  32   0.68 
02960                                                                  32   0.95 
34005                                                                  32   1.0  
12841                                                                  32   1.2  
10162                                                                  32   1.3  
04358                                                                  32   1.4  
31474                                                                  31   1.5  
38362                                                                  31   1.7  
14555                                                                  31   2.0  
18320                                                                  31   2.2  
21960                                                                  30   2.5  
05393                                                                  30   3.3  
01805                                                                  30   3.4  
34511                                                                  30   3.5  
08679                                                                  30   3.9  
30295                                                                  30   4.5  
31864                                                                  30   4.8  
30297                                                                  29   8.9  
>04732
          Length = 963

 Score =  246 bits (629), Expect = 2e-65,   Method: Compositional matrix adjust.
 Identities = 148/321 (46%), Positives = 196/321 (61%), Gaps = 31/321 (9%)
 Frame = -2

Query: 59  RPQQYTIPGILHYIQHEWARFEMERAHWEVERAELQARIAFLQGERKGQENLKKDLVRRI 118
           RPQ +++PGILH++Q EWARFEMER+ WEVERAELQARIAFLQGERKGQENLK+DLVRRI
Sbjct: 911 RPQ-FSMPGILHFLQTEWARFEMERSQWEVERAELQARIAFLQGERKGQENLKQDLVRRI 735

Query: 119 KMLEYALKQERAKYHKLKYGTELNQGDLKMPTFESEETKDVEAPP--APQNSQLTWKQGR 176
           KMLE+ALKQER KYHKLKYGT++N  +L   ++E ++   +  P   +P N+ + WKQGR
Sbjct: 734 KMLEFALKQERGKYHKLKYGTDMNSDELTQSSYEKKDDDQMGEPAMSSPANTNIEWKQGR 555

Query: 177 QLLRQYLQEVGYTDTILDVRSQRVRSLLGLSNSEPNGSVEAKNLEQILNGGESPKQK--- 233
           QLLRQYLQE+GY+DTI+DVRS RVRSLLGL   +P   V+  N  ++ NG   P+++   
Sbjct: 554 QLLRQYLQEIGYSDTIIDVRSARVRSLLGL---QPASDVDGDNQPELTNG--KPEKRDGT 390

Query: 234 GQEI--KRPPG-------------DVLETFNFLXXXXXXXXXXXXM------IEGIPEGK 272
           G+ +  KR PG              ++ TF+FL            +      +    E  
Sbjct: 389 GKRVGLKRLPGIGPMDSALMDTENSIMSTFDFLAGDSDIDEGENNLGDESDGLTADDESD 210

Query: 273 DKLR---IHKHKIGNEGLAA-DLTDDPDTEEALKEFDFLVTAEDGEGAGEARSSGDGTEW 328
           ++L    +    +GN+ ++  DL +DP+TEE + +FD LV                  E 
Sbjct: 209 ERLERKGVKTKVLGNDQMSGLDLLEDPETEEVMAQFDILV-----------------RES 81

Query: 329 DKDDLSPTAEV-WDVDQGLIS 348
           +K D  PT  V W VDQ  IS
Sbjct: 80  EKKD--PTCNVEWSVDQRHIS 24
>09899
          Length = 1401

 Score =  218 bits (556), Expect = 6e-57,   Method: Compositional matrix adjust.
 Identities = 112/175 (64%), Positives = 134/175 (76%), Gaps = 4/175 (2%)
 Frame = +1

Query: 69  LHYIQHEWARFEMERAHWEVERAELQARIAFLQGERKGQENLKKDLVRRIKMLEYALKQE 128
           L ++Q EWARFEMER+ WEVERAELQARIAFLQGERKGQENLK+DLVRRIKMLE+ALKQE
Sbjct: 79  LAFLQTEWARFEMERSQWEVERAELQARIAFLQGERKGQENLKQDLVRRIKMLEFALKQE 258

Query: 129 RAKYHKLKYGTELNQGDLKMPTFESEETKDVEAPP---APQNSQLTWKQGRQLLRQYLQE 185
           R KYHKLKYGT++N  DLK P FE ++   ++  P   +  NS   WKQGRQLLRQYLQE
Sbjct: 259 RGKYHKLKYGTDMNPEDLKPPVFEKKDEDQLDGEPSMTSSANSNTQWKQGRQLLRQYLQE 438

Query: 186 VGYTDTILDVRSQRVRSLLGLSNSEP-NGSVEAKNLEQILNGGESPKQKGQEIKR 239
           +GYTDTI+DVRS RVRSLLGL   +P +G  E   L  ++NG +   ++  + KR
Sbjct: 439 IGYTDTIIDVRSARVRSLLGL---QPVSGDNENDGLSALVNGEQQMGKRDNQGKR 594

 Score = 40.0 bits (92), Expect(2) = 3e-08,   Method: Compositional matrix adjust.
 Identities = 33/76 (43%), Positives = 37/76 (48%), Gaps = 1/76 (1%)
 Frame = +3

Query: 274 KLRIHKHKIGNEGLAA-DLTDDPDTEEALKEFDFLVTAEDGEGAGEARSSGDGTEWDKDD 332
           K R      GNE +A  DL DDP+ EEAL EFDFLV   D E               K D
Sbjct: 783 KKRCQTEGGGNESMAGEDLLDDPEAEEALAEFDFLVP--DSE---------------KKD 911

Query: 333 LSPTAEVWDVDQGLIS 348
           ++  AE W VDQ  IS
Sbjct: 912 VTSNAE-WSVDQRHIS 956

 Score = 36.2 bits (82), Expect(2) = 3e-08,   Method: Compositional matrix adjust.
 Identities = 35/113 (30%), Positives = 48/113 (42%), Gaps = 11/113 (9%)
 Frame = +1

Query: 369  RTNLCDMITDLG-DDELPHIPSGIINQSRSASTRMADHEGARAEEAEPITFPSGGGKSFI 427
            R+ L  M+ +LG ++ELP+ PS         S     HE A   +A+     SGGG  F 
Sbjct: 1012 RSALQAMLANLGSEEELPNFPS-------EPSGTATSHE-AEEVDADDTGMQSGGGLGFS 1167

Query: 428  MXXXXXXXXXXXXXXXXXX---------TVTNDADYS-YDLPANKDAFRKTWN 470
                                        T++N+AD S YD+ A K+ FRKTWN
Sbjct: 1168 PTSRKPMLGGSDEDEFSNALGLGELAGITISNEADPSNYDISAPKEVFRKTWN 1326

 Score = 41.6 bits (96), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 22/36 (61%), Positives = 25/36 (69%), Gaps = 1/36 (2%)
 Frame = +3

Query: 460  ANKDAFRKTWNPKYTLRSHFDGVRALAFHP-VEPVL 494
              K +F +    KYTLRSHFDGVRALAF P  +PVL
Sbjct: 1293 GTKRSF*EDMECKYTLRSHFDGVRALAFQP**DPVL 1400
>21105
          Length = 650

 Score =  207 bits (528), Expect = 1e-53,   Method: Compositional matrix adjust.
 Identities = 94/108 (87%), Positives = 104/108 (96%)
 Frame = +1

Query: 689 HPTLPVTITAHEDRHIKFFDNKTGKMIHSMVAHLDAVTSLAVDPNGIYLMSGSHDCSIRL 748
           HPT+P+TITAHEDRHI+FFDN TGK+IH+MVAHLD+VTSLAVDPNG+YL+SGSHDCSIRL
Sbjct: 91  HPTMPITITAHEDRHIRFFDNNTGKLIHAMVAHLDSVTSLAVDPNGLYLLSGSHDCSIRL 270

Query: 749 WNLDSKTCVQEITAHRKKLDESIYDVAFHPSKAYIASAGADALAKVFV 796
           WNLDSKTCVQEIT+HRKK DESI+DVAFHP K YIASAGADALAKVFV
Sbjct: 271 WNLDSKTCVQEITSHRKKFDESIHDVAFHPQKPYIASAGADALAKVFV 414

 Score = 42.0 bits (97), Expect = 8e-04,   Method: Composition-based stats.
 Identities = 24/76 (31%), Positives = 37/76 (48%)
 Frame = +1

Query: 488 HPVEPVLVTASEDHTLKLWNLQKTVPAKKSASLDVEPIYTFRAHIGPVLSLAISSNGEQC 547
           HP  P+ +TA ED  ++ ++         +  L    I+   AH+  V SLA+  NG   
Sbjct: 91  HPTMPITITAHEDRHIRFFD-------NNTGKL----IHAMVAHLDSVTSLAVDPNGLYL 237

Query: 548 FSGGIDATIQWWNMPS 563
            SG  D +I+ WN+ S
Sbjct: 238 LSGSHDCSIRLWNLDS 285

 Score = 31.2 bits (69), Expect = 1.6,   Method: Composition-based stats.
 Identities = 19/41 (46%), Positives = 22/41 (53%)
 Frame = +1

Query: 577 LAGTLVAHTDAVWGLAYSGIKNQLLSCSADGTIRLWNPQEK 617
           L   +VAH D+V  LA       LLS S D +IRLWN   K
Sbjct: 166 LIHAMVAHLDSVTSLAVDPNGLYLLSGSHDCSIRLWNLDSK 288

 Score = 31.2 bits (69), Expect = 1.8,   Method: Composition-based stats.
 Identities = 13/36 (36%), Positives = 22/36 (61%)
 Frame = +1

Query: 473 YTLRSHFDGVRALAFHPVEPVLVTASEDHTLKLWNL 508
           + + +H D V +LA  P    L++ S D +++LWNL
Sbjct: 172 HAMVAHLDSVTSLAVDPNGLYLLSGSHDCSIRLWNL 279
>30256
          Length = 961

 Score = 59.7 bits (143), Expect = 4e-09,   Method: Compositional matrix adjust.
 Identities = 52/215 (24%), Positives = 93/215 (43%)
 Frame = +3

Query: 581 LVAHTDAVWGLAYSGIKNQLLSCSADGTIRLWNPQEKLPCVCTYNGDKEHGIPTSVDFIG 640
           L+ HT  VW    +G  N ++S S D ++++WN       VCT+     +G  ++V  + 
Sbjct: 30  LIGHTGGVWSSQMTG--NTVISGSTDRSLKVWNADTG---VCTHT---LYGHSSTVRCLS 185

Query: 641 CDPAHMVTSFNTGSAVIYDLETSQSLVMLSSQVDSGLQSSNHINRVVSHPTLPVTITAHE 700
                +V+     +  ++D+E+   L +L   + +         RVVS            
Sbjct: 186 LSGKKVVSGSRDATLRVWDIESGHCLNVLLGHMAAVRCVQYDGKRVVS---------GAX 338

Query: 701 DRHIKFFDNKTGKMIHSMVAHLDAVTSLAVDPNGIYLMSGSHDCSIRLWNLDSKTCVQEI 760
           D  ++ +D  T   +H++  H + V SL  D  G+Y++SGS D SIR+W++     V  +
Sbjct: 339 DYTVRVWDPDTASCLHTLQGHTNRVYSLQFD--GVYVVSGSLDTSIRVWDVRCGKLVHTL 512

Query: 761 TAHRKKLDESIYDVAFHPSKAYIASAGADALAKVF 795
             H+                  + S  AD+  KV+
Sbjct: 513 MGHQS------LTSGLELKDNLLVSGNADSTVKVW 599

 Score = 58.5 bits (140), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 63/277 (22%), Positives = 118/277 (42%), Gaps = 4/277 (1%)
 Frame = +3

Query: 523 EPIYTFRAHIGPVLSLAISSNGEQCFSGGIDATIQWWNMPSPNVDPYDTYESNVLAGTLV 582
             I     H G V S  ++  G    SG  D +++ WN            ++ V   TL 
Sbjct: 15  RCIKNLIGHTGGVWSSQMT--GNTVISGSTDRSLKVWNA-----------DTGVCTHTLY 155

Query: 583 AHTDAVWGLAYSGIKNQLLSCSADGTIRLWNPQEKLPCVCTYNGDKEHGIPTSVDFIGCD 642
            H+  V  L+ SG K  ++S S D T+R+W+  E   C+     +   G   +V  +  D
Sbjct: 156 GHSSTVRCLSLSGKK--VVSGSRDATLRVWDI-ESGHCL-----NVLLGHMAAVRCVQYD 311

Query: 643 PAHMVTSFNTGSAVIYDLETSQSLVMLSSQVDSGLQSSNHINRVVSHPTLPV-TITAHED 701
              +V+     +  ++D +T+  L  L            H NRV S     V  ++   D
Sbjct: 312 GKRVVSGAXDYTVRVWDPDTASCLHTLQG----------HTNRVYSLQFDGVYVVSGSLD 461

Query: 702 RHIKFFDNKTGKMIHSMVAHLDAVTSLAVDPNGIYLMSGSHDCSIRLWNLDSKTCVQEIT 761
             I+ +D + GK++H+++ H    + L +  N   L+SG+ D ++++W++ +  C+Q + 
Sbjct: 462 TSIRVWDVRCGKLVHTLMGHQSLTSGLELKDN--LLVSGNADSTVKVWDVHTGKCLQTLL 635

Query: 762 A---HRKKLDESIYDVAFHPSKAYIASAGADALAKVF 795
               HR  +           +K ++ +   D   K++
Sbjct: 636 GPNKHRSAV------TCLQFNKKFVVTCSDDGTVKLW 728

 Score = 35.4 bits (80), Expect = 0.085,   Method: Compositional matrix adjust.
 Identities = 38/155 (24%), Positives = 70/155 (45%), Gaps = 8/155 (5%)
 Frame = +3

Query: 467 KTWNPK-----YTLRSHFDGVRALAFHPVEPVLVTASEDHTLKLWNLQKTVPAKKSASLD 521
           + W+P      +TL+ H + V +L F  V   +V+ S D ++++W+++            
Sbjct: 351 RVWDPDTASCLHTLQGHTNRVYSLQFDGVY--VVSGSLDTSIRVWDVRCG---------- 494

Query: 522 VEPIYTFRAHIGPVLSLAISSNGEQCFSGGIDATIQWWNMPSPNVDPYDTYESNVLAGTL 581
            + ++T   H      L +  N     SG  D+T++ W          D +    L  TL
Sbjct: 495 -KLVHTLMGHQSLTSGLELKDN--LLVSGNADSTVKVW----------DVHTGKCLQ-TL 632

Query: 582 VA---HTDAVWGLAYSGIKNQLLSCSADGTIRLWN 613
           +    H  AV  L ++  K  +++CS DGT++LW+
Sbjct: 633 LGPNKHRSAVTCLQFN--KKFVVTCSDDGTVKLWD 731
>17598
          Length = 875

 Score = 55.8 bits (133), Expect = 6e-08,   Method: Compositional matrix adjust.
 Identities = 60/292 (20%), Positives = 111/292 (38%), Gaps = 2/292 (0%)
 Frame = +1

Query: 494 LVTASEDHTLKLWNLQKTVPAKKSASLDV--EPIYTFRAHIGPVLSLAISSNGEQCFSGG 551
           L+    D  L +W+L   VP K     +    P  T + H   V  +++S++     S  
Sbjct: 10  LIXGGRDKLLIVWDL---VPRKDGDEDETWGGPRRTLQGHSHFVSDVSLSADSRYVLSSS 180

Query: 552 IDATIQWWNMPSPNVDPYDTYESNVLAGTLVAHTDAVWGLAYSGIKNQLLSCSADGTIRL 611
            DAT++ W++   N                ++HT     +A+S    Q+ S   D  +++
Sbjct: 181 WDATLRLWDIKKGNT-----------TRRFISHTRDALAVAFSPDNRQIASGGRDKALKI 327

Query: 612 WNPQEKLPCVCTYNGDKEHGIPTSVDFIGCDPAHMVTSFNTGSAVIYDLETSQSLVMLSS 671
           WN   +    C +  D      +  D++ C   H               + ++S      
Sbjct: 328 WNTVGE----CKFTVDAN----SHQDWVTCVKFH---------------QDAKS------ 420

Query: 672 QVDSGLQSSNHINRVVSHPTLPVTITAHEDRHIKFFDNKTGKMIHSMVAHLDAVTSLAVD 731
                                P+ ++A  D+ IK +DN+T  + H+ V H   + ++ + 
Sbjct: 421 ---------------------PLVVSASMDKTIKVWDNQTMTLKHTFVGHKTQINAIDLA 537

Query: 732 PNGIYLMSGSHDCSIRLWNLDSKTCVQEITAHRKKLDESIYDVAFHPSKAYI 783
               YL SGS D  +  WN+ + T + +I       D  +  V F P+K ++
Sbjct: 538 LKTYYLASGSKDGIVMTWNIQNGTFLGKIDC-----DCEVNAVKFSPNKYWL 678

 Score = 46.6 bits (109), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 42/162 (25%), Positives = 70/162 (43%), Gaps = 2/162 (1%)
 Frame = +1

Query: 456 YDLPANKDAFR-KTWN-PKYTLRSHFDGVRALAFHPVEPVLVTASEDHTLKLWNLQKTVP 513
           +DL   KD    +TW  P+ TL+ H   V  ++       ++++S D TL+LW+++K   
Sbjct: 46  WDLVPRKDGDEDETWGGPRRTLQGHSHFVSDVSLSADSRYVLSSSWDATLRLWDIKKGNT 225

Query: 514 AKKSASLDVEPIYTFRAHIGPVLSLAISSNGEQCFSGGIDATIQWWNMPSPNVDPYDTYE 573
            ++           F +H    L++A S +  Q  SGG D  ++ WN         D   
Sbjct: 226 TRR-----------FISHTRDALAVAFSPDNRQIASGGRDKALKIWNTVGECKFTVDANS 372

Query: 574 SNVLAGTLVAHTDAVWGLAYSGIKNQLLSCSADGTIRLWNPQ 615
                  +  H DA   L        ++S S D TI++W+ Q
Sbjct: 373 HQDWVTCVKFHQDAKSPL--------VVSASMDKTIKVWDNQ 474

 Score = 38.9 bits (89), Expect = 0.009,   Method: Compositional matrix adjust.
 Identities = 20/79 (25%), Positives = 38/79 (48%)
 Frame = +1

Query: 717 SMVAHLDAVTSLAVDPNGIYLMSGSHDCSIRLWNLDSKTCVQEITAHRKKLDESIYDVAF 776
           ++  H   V+ +++  +  Y++S S D ++RLW++      +   +H +        VAF
Sbjct: 106 TLQGHSHFVSDVSLSADSRYVLSSSWDATLRLWDIKKGNTTRRFISHTR----DALAVAF 273

Query: 777 HPSKAYIASAGADALAKVF 795
            P    IAS G D   K++
Sbjct: 274 SPDNRQIASGGRDKALKIW 330
>01598
          Length = 1545

 Score = 54.7 bits (130), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 49/205 (23%), Positives = 88/205 (42%), Gaps = 19/205 (9%)
 Frame = +1

Query: 604 SADGTIRLWNPQE-------KLPCVCTYNGD--KEHGIPTSVDFIGCDPAHMVTSFNTGS 654
           S D TIR+W   +       KLP      GD      +  ++ ++  +P  +V+S + G 
Sbjct: 121 SKDRTIRVWTLSQGKQIFMKKLPNQRREAGDTGSRFKVWLAIHWLKSNPEQLVSSSSGGD 300

Query: 655 AVIYDLETSQSLVMLSSQVDSGLQSSNH-------INRVVSHPTLPVTITAHEDRHIKFF 707
            +++ L  ++       Q     Q+S++        N   S P      T  +DR +  +
Sbjct: 301 LLLWSLRYTKG------QAYQTFQTSDYRPHMRPVFNICASGPDSKTLCTFAQDRQVVLW 462

Query: 708 DNKTGKMIHSMV---AHLDAVTSLAVDPNGIYLMSGSHDCSIRLWNLDSKTCVQEITAHR 764
           D +T + + SM     H+  V +  +DP  + +  G  D  IR WN+ +KT   ++T   
Sbjct: 463 DLETMEAVASMATLGGHVYCVRTSPIDPGRVAV--GVGDSMIRTWNMSNKTNPYDVTTLW 636

Query: 765 KKLDESIYDVAFHPSKAYIASAGAD 789
           + +   +  VA+HP+K      G D
Sbjct: 637 QGIKSKVTAVAWHPTKEGWLGFGTD 711
>19949
          Length = 903

 Score = 54.3 bits (129), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 28/107 (26%), Positives = 52/107 (48%)
 Frame = +2

Query: 689 HPTLPVTITAHEDRHIKFFDNKTGKMIHSMVAHLDAVTSLAVDPNGIYLMSGSHDCSIRL 748
           HP    T +   D ++K +D +    I++   H   V  L   P+G ++ S S D  ++L
Sbjct: 20  HPYGAYTASGSMDCNVKLWDIRRKGCIYTYKGHTGCVCCLRFSPDGRWIASASEDGLVKL 199

Query: 749 WNLDSKTCVQEITAHRKKLDESIYDVAFHPSKAYIASAGADALAKVF 795
           W+L +   + ++  HR    +++  + FHP +  +AS  AD   K +
Sbjct: 200 WDLTAGKLLTDLKLHR----DAVNTIEFHPHEFLLASGSADRTVKFW 328

 Score = 51.2 bits (121), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 35/132 (26%), Positives = 57/132 (43%)
 Frame = +2

Query: 482 VRALAFHPVEPVLVTASEDHTLKLWNLQKTVPAKKSASLDVEPIYTFRAHIGPVLSLAIS 541
           V++L FHP      + S D  +KLW++++              IYT++ H G V  L  S
Sbjct: 2   VKSLDFHPYGAYTASGSMDCNVKLWDIRRK-----------GCIYTYKGHTGCVCCLRFS 148

Query: 542 SNGEQCFSGGIDATIQWWNMPSPNVDPYDTYESNVLAGTLVAHTDAVWGLAYSGIKNQLL 601
            +G    S   D  ++ W++            +  L   L  H DAV  + +   +  L 
Sbjct: 149 PDGRWIASASEDGLVKLWDL-----------TAGKLLTDLKLHRDAVNTIEFHPHEFLLA 295

Query: 602 SCSADGTIRLWN 613
           S SAD T++ W+
Sbjct: 296 SGSADRTVKFWD 331

 Score = 50.1 bits (118), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 31/99 (31%), Positives = 52/99 (52%)
 Frame = +2

Query: 697 TAHEDRHIKFFDNKTGKMIHSMVAHLDAVTSLAVDPNGIYLMSGSHDCSIRLWNLDSKTC 756
           +A ED  +K +D   GK++  +  H DAV ++   P+   L SGS D +++ W+L++   
Sbjct: 170 SASEDGLVKLWDLTAGKLLTDLKLHRDAVNTIEFHPHEFLLASGSADRTVKFWDLET--- 340

Query: 757 VQEITAHRKKLDESIYDVAFHPSKAYIASAGADALAKVF 795
            Q I+    + + SI  + FHP    + S   D L KV+
Sbjct: 341 FQLISTTEPEAN-SIRSILFHPDGVCLYSGSKDTL-KVY 451

 Score = 49.7 bits (117), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 25/71 (35%), Positives = 36/71 (50%)
 Frame = +2

Query: 725 VTSLAVDPNGIYLMSGSHDCSIRLWNLDSKTCVQEITAHRKKLDESIYDVAFHPSKAYIA 784
           V SL   P G Y  SGS DC+++LW++  K C+     H       +  + F P   +IA
Sbjct: 2   VKSLDFHPYGAYTASGSMDCNVKLWDIRRKGCIYTYKGHTG----CVCCLRFSPDGRWIA 169

Query: 785 SAGADALAKVF 795
           SA  D L K++
Sbjct: 170 SASEDGLVKLW 202

 Score = 47.8 bits (112), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 37/142 (26%), Positives = 66/142 (46%)
 Frame = +2

Query: 602 SCSADGTIRLWNPQEKLPCVCTYNGDKEHGIPTSVDFIGCDPAHMVTSFNTGSAVIYDLE 661
           S S D  ++LW+ + K  C+ TY G    G    + F   D   + ++   G   ++DL 
Sbjct: 44  SGSMDCNVKLWDIRRK-GCIYTYKGHT--GCVCCLRF-SPDGRWIASASEDGLVKLWDLT 211

Query: 662 TSQSLVMLSSQVDSGLQSSNHINRVVSHPTLPVTITAHEDRHIKFFDNKTGKMIHSMVAH 721
             + L  L    D+       +N +  HP   +  +   DR +KF+D +T ++I +    
Sbjct: 212 AGKLLTDLKLHRDA-------VNTIEFHPHEFLLASGSADRTVKFWDLETFQLISTTEPE 370

Query: 722 LDAVTSLAVDPNGIYLMSGSHD 743
            +++ S+   P+G+ L SGS D
Sbjct: 371 ANSIRSILFHPDGVCLYSGSKD 436

 Score = 37.0 bits (84), Expect = 0.027,   Method: Compositional matrix adjust.
 Identities = 37/151 (24%), Positives = 62/151 (41%), Gaps = 5/151 (3%)
 Frame = +2

Query: 455 SYDLPANKDAFRKTWNPK-----YTLRSHFDGVRALAFHPVEPVLVTASEDHTLKLWNLQ 509
           +Y    + D   K W+ +     YT + H   V  L F P    + +ASED  +KLW+L 
Sbjct: 32  AYTASGSMDCNVKLWDIRRKGCIYTYKGHTGCVCCLRFSPDGRWIASASEDGLVKLWDLT 211

Query: 510 KTVPAKKSASLDVEPIYTFRAHIGPVLSLAISSNGEQCFSGGIDATIQWWNMPSPNVDPY 569
                        + +   + H   V ++    +     SG  D T+++W++ +  +   
Sbjct: 212 AG-----------KLLTDLKLHRDAVNTIEFHPHEFLLASGSADRTVKFWDLETFQLIST 358

Query: 570 DTYESNVLAGTLVAHTDAVWGLAYSGIKNQL 600
              E+N +   L  H D V    YSG K+ L
Sbjct: 359 TEPEANSIRSILF-HPDGV--CLYSGSKDTL 442
>02147
          Length = 1547

 Score = 53.9 bits (128), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 52/256 (20%), Positives = 102/256 (39%)
 Frame = +2

Query: 495 VTASEDHTLKLWNLQKTVPAKKSASLDVEPIYTFRAHIGPVLSLAISSNGEQCFSGGIDA 554
            T + D + K+W+ +K            E + TF +H   V S+  S +G    +G  + 
Sbjct: 221 ATGAADFSAKIWDAEKG-----------EELQTF-SHKHIVKSVDFSHDGTALLTGSNEK 364

Query: 555 TIQWWNMPSPNVDPYDTYESNVLAGTLVAHTDAVWGLAYSGIKNQLLSCSADGTIRLWNP 614
            ++ +++ + + +P           +   HT  + G  +     +++S S D T+RLW+ 
Sbjct: 365 LLKVFDLVNTDAEP----------KSFAGHTSNIKGALFLSDGKRIISASDDKTVRLWSL 514

Query: 615 QEKLPCVCTYNGDKEHGIPTSVDFIGCDPAHMVTSFNTGSAVIYDLETSQSLVMLSSQVD 674
           +      C          P +   +  D   ++ + ++ +   Y  +T + +    ++  
Sbjct: 515 E-----TCQEVQQLTFDTPPTSLTLSPDKNTIIVT-HSQNIAFYQADTLREMKKFEAEAP 676

Query: 675 SGLQSSNHINRVVSHPTLPVTITAHEDRHIKFFDNKTGKMIHSMVAHLDAVTSLAVDPNG 734
                   I+    H +    +   ED  +  FD +TGK I S   H   V  +   P+G
Sbjct: 677 --------ISSASLHQSERFFVAGGEDFKMYKFDYETGKEIESFKGHFGPVHCVRFSPDG 832

Query: 735 IYLMSGSHDCSIRLWN 750
               SGS D ++RLW 
Sbjct: 833 ELYASGSEDGTLRLWQ 880

 Score = 31.6 bits (70), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 46/215 (21%), Positives = 94/215 (43%), Gaps = 4/215 (1%)
 Frame = +2

Query: 579 GTLVAHTDAVWGLAYSGIKNQLLSCSADGTIRLWNPQEKLPCVCTYNGDKEHGIPTSVDF 638
           GT   H  AVWG   +    +  + +AD + ++W+  EK   + T++   +H I  SVDF
Sbjct: 155 GTFEGHKGAVWGATLNREATRAATGAADFSAKIWDA-EKGEELQTFS--HKH-IVKSVDF 322

Query: 639 IGCDPAHMVTSFNTGSAVIYDLETS----QSLVMLSSQVDSGLQSSNHINRVVSHPTLPV 694
              D   ++T  N     ++DL  +    +S    +S +   L  S+   R++S      
Sbjct: 323 -SHDGTALLTGSNEKLLKVFDLVNTDAEPKSFAGHTSNIKGALFLSDG-KRIIS------ 478

Query: 695 TITAHEDRHIKFFDNKTGKMIHSMVAHLDAVTSLAVDPNGIYLMSGSHDCSIRLWNLDSK 754
              A +D+ ++ +  +T + +  +       TSL + P+   ++  +H  +I  +  D+ 
Sbjct: 479 ---ASDDKTVRLWSLETCQEVQQLTFDTPP-TSLTLSPDKNTIIV-THSQNIAFYQADTL 643

Query: 755 TCVQEITAHRKKLDESIYDVAFHPSKAYIASAGAD 789
             +++  A     +  I   + H S+ +  + G D
Sbjct: 644 REMKKFEA-----EAPISSASLHQSERFFVAGGED 733

 Score = 29.6 bits (65), Expect = 4.6,   Method: Compositional matrix adjust.
 Identities = 12/34 (35%), Positives = 18/34 (52%)
 Frame = +2

Query: 474 TLRSHFDGVRALAFHPVEPVLVTASEDHTLKLWN 507
           + + HF  V  + F P   +  + SED TL+LW 
Sbjct: 779 SFKGHFGPVHCVRFSPDGELYASGSEDGTLRLWQ 880
>12806
          Length = 961

 Score = 53.1 bits (126), Expect = 4e-07,   Method: Compositional matrix adjust.
 Identities = 57/270 (21%), Positives = 100/270 (37%)
 Frame = +3

Query: 491 EPVLVTASEDHTLKLWNLQKTVPAKKSASLDVEPIYTFRAHIGPVLSLAISSNGEQCFSG 550
           +P L++   D+ + +W+L       +  +  V P  T   H   +  LA+S++     S 
Sbjct: 45  KPFLISGGRDNNIIVWDL*PKKDGDEDQTWGV-PRKTLTGHSHFISDLALSADSRFALSS 221

Query: 551 GIDATIQWWNMPSPNVDPYDTYESNVLAGTLVAHTDAVWGLAYSGIKNQLLSCSADGTIR 610
             DAT++ W++   +                + HT  V  +A+S    Q+ S   D  ++
Sbjct: 222 SWDATLRLWDIKKGST-----------TSRFINHTRDVLTVAFSPDNRQIASGGRDKNLK 368

Query: 611 LWNPQEKLPCVCTYNGDKEHGIPTSVDFIGCDPAHMVTSFNTGSAVIYDLETSQSLVMLS 670
           +WN   +    C Y  D         D++ C   H  T                      
Sbjct: 369 IWNIMGE----CKYTVDAN----AHTDWVTCVRFHQDTKN-------------------- 464

Query: 671 SQVDSGLQSSNHINRVVSHPTLPVTITAHEDRHIKFFDNKTGKMIHSMVAHLDAVTSLAV 730
                                 P+ ++A  D+ IK +DN T  + ++ V H   +T+L +
Sbjct: 465 ----------------------PIVVSASNDKTIKVWDNHTMTLKNTFVGHKAQITALDM 578

Query: 731 DPNGIYLMSGSHDCSIRLWNLDSKTCVQEI 760
             N  YL+SGS D     WN+   + V +I
Sbjct: 579 STN--YLVSGSKDGIAMTWNVAEGSFVGKI 662

 Score = 47.8 bits (112), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 47/162 (29%), Positives = 75/162 (46%), Gaps = 4/162 (2%)
 Frame = +3

Query: 456 YDLPANKDAFR-KTWN-PKYTLRSHFDGVRALAFHPVEPVLVTASEDHTLKLWNLQKTVP 513
           +DL   KD    +TW  P+ TL  H   +  LA        +++S D TL+LW+++K   
Sbjct: 90  WDL*PKKDGDEDQTWGVPRKTLTGHSHFISDLALSADSRFALSSSWDATLRLWDIKKGST 269

Query: 514 AKKSASLDVEPIYTFRAHIGPVLSLAISSNGEQCFSGGIDATIQWWNMPSPNVDPYDTYE 573
             +           F  H   VL++A S +  Q  SGG D  ++ WN+     +   T +
Sbjct: 270 TSR-----------FINHTRDVLTVAFSPDNRQIASGGRDKNLKIWNIMG---ECKYTVD 407

Query: 574 SNVLAGTLVAHTDAVWGLAY-SGIKNQL-LSCSADGTIRLWN 613
           +N       AHTD V  + +    KN + +S S D TI++W+
Sbjct: 408 AN-------AHTDWVTCVRFHQDTKNPIVVSASNDKTIKVWD 512

 Score = 41.6 bits (96), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 29/121 (23%), Positives = 50/121 (41%), Gaps = 10/121 (8%)
 Frame = +3

Query: 685 RVVSHPTLPVTITAHEDRHIKFFD----------NKTGKMIHSMVAHLDAVTSLAVDPNG 734
           +VV   T P  I+   D +I  +D             G    ++  H   ++ LA+  + 
Sbjct: 24  QVVDGATKPFLISGGRDNNIIVWDL*PKKDGDEDQTWGVPRKTLTGHSHFISDLALSADS 203

Query: 735 IYLMSGSHDCSIRLWNLDSKTCVQEITAHRKKLDESIYDVAFHPSKAYIASAGADALAKV 794
            + +S S D ++RLW++   +       H +     +  VAF P    IAS G D   K+
Sbjct: 204 RFALSSSWDATLRLWDIKKGSTTSRFINHTR----DVLTVAFSPDNRQIASGGRDKNLKI 371

Query: 795 F 795
           +
Sbjct: 372 W 374
>01327
          Length = 2215

 Score = 52.0 bits (123), Expect = 9e-07,   Method: Compositional matrix adjust.
 Identities = 54/239 (22%), Positives = 92/239 (38%), Gaps = 12/239 (5%)
 Frame = +3

Query: 569 YDTYESNVLAGTLVAHTDAVWGLAYSGIKNQLLSCSADGTIRLWNPQEKLPCVCTYNGDK 628
           YD Y++  L      H   +  + Y    N + S S D TI++W                
Sbjct: 120 YD-YQNGRLEDRWTGHDREITKVCYGASCNGMFSASRDKTIKMWQR------------GN 260

Query: 629 EHGIPTSVDFIGCDPAHMVTSFNTGSAVIYDLETSQSLVMLSSQVDSGLQSSNHINRVVS 688
            H I    DFIG D        NT + ++       ++ +   +  + L+ +N    +V+
Sbjct: 261 SHSIR---DFIGHDMVVTAIHLNTDNTLLCSGSRDNTVRIWDVETGACLRQNNIPQNLVT 431

Query: 689 H----PTLPVTITAHEDRHIKFFDNKTGKMIHSMVAHLDAVTSLAVDPNGIYLMS----- 739
                P   + I A ED+ ++ +D++T  ++ S         S  V  +G + ++     
Sbjct: 432 DVKWLPGSHLIIQAGEDKEVRIYDSRTLGIVRSFTKKQYIQMSCDVTADGQFCLTCSNGF 611

Query: 740 GSHDCSIRLWNLDSKTCVQEITAHRKKLDESIYDVAFHPSK---AYIASAGADALAKVF 795
           G + C   LW L   +   E   HR    E+I    F PS      IA+A  D   +V+
Sbjct: 612 GGNGCEATLWQLSDGSIQNEFKGHR----EAIEACLFLPSNQDMTLIATASRDCSVRVW 776
>03156
          Length = 1014

 Score = 50.1 bits (118), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 50/225 (22%), Positives = 86/225 (38%), Gaps = 12/225 (5%)
 Frame = +1

Query: 583 AHTDAVWGLAYSGIKNQLLSCSADGTIRLWNPQEKLPCVCTYNGDKEHGIPTSVDFIGCD 642
            H   +  + Y    N + S S D TI++W                 H I    DFIG D
Sbjct: 49  GHDREITKVCYGASCNGMFSASRDKTIKMWQR------------GNSHSIR---DFIGHD 183

Query: 643 PAHMVTSFNTGSAVIYDLETSQSLVMLSSQVDSGLQSSNHINRVVSH----PTLPVTITA 698
                   NT + ++       ++ +   +  + L+ +N    +V+     P   + I A
Sbjct: 184 MVVTAIHLNTDNTLLCSGSRDNTVRIWDVETGACLRQNNIPQNLVTDVKWLPGSHLIIQA 363

Query: 699 HEDRHIKFFDNKTGKMIHSMVAHLDAVTSLAVDPNGIYLMS-----GSHDCSIRLWNLDS 753
            ED+ ++ +D++T  ++ S         S  V  +G + ++     G + C   LW L  
Sbjct: 364 GEDKEVRIYDSRTLGIVRSFTKKQYIQMSCDVTADGQFCLTCSNGFGGNGCEATLWQLSD 543

Query: 754 KTCVQEITAHRKKLDESIYDVAFHPSK---AYIASAGADALAKVF 795
            +   E   HR    E+I    F PS      IA+A  D   +V+
Sbjct: 544 GSIQNEFKGHR----EAIEACLFLPSNQDMTLIATASRDCSVRVW 666
>00561
          Length = 1003

 Score = 49.7 bits (117), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 63/303 (20%), Positives = 113/303 (37%), Gaps = 1/303 (0%)
 Frame = -3

Query: 485 LAFHPVEP-VLVTASEDHTLKLWNLQKTVPAKKSASLDVEPIYTFRAHIGPVLSLAISSN 543
           +A +P +P  +++AS D TL +W L +             P      H   +  + +SS+
Sbjct: 995 IATNPKDPDTIISASRDKTLIVWKLTRDEDTNYG-----YPQKRLYGHSHFISDVVLSSD 831

Query: 544 GEQCFSGGIDATIQWWNMPSPNVDPYDTYESNVLAGTLVAHTDAVWGLAYSGIKNQLLSC 603
           G    SG  D T++ W++            +         HT  V  +A+S    Q++S 
Sbjct: 830 GNYALSGSWDQTLRLWDL-----------AAGKTTRRFEGHTKDVLSVAFSADNRQIVSG 684

Query: 604 SADGTIRLWNPQEKLPCVCTYNGDKEHGIPTSVDFIGCDPAHMVTSFNTGSAVIYDLETS 663
           S D TI+LWN   +  C  T   D         D++ C        F             
Sbjct: 683 SRDKTIKLWNTLAE--CKFTIQEDGH------TDWVSC------VRF------------- 585

Query: 664 QSLVMLSSQVDSGLQSSNHINRVVSHPTLPVTITAHEDRHIKFFDNKTGKMIHSMVAHLD 723
                          S NH N        P+ ++   DR +K ++    K+ ++   H  
Sbjct: 584 ---------------SPNHSN--------PIIVSCGWDRTVKVWNLANCKLKNNHHGHNG 474

Query: 724 AVTSLAVDPNGIYLMSGSHDCSIRLWNLDSKTCVQEITAHRKKLDESIYDVAFHPSKAYI 783
            + ++ V P+G    SG  D    LW+L+    +  +     + ++ I  + F P++ ++
Sbjct: 473 YLNTVTVSPDGSLCTSGGKDSKALLWDLNDGKNLYTL-----EHNDIINALCFSPNRYWL 309

Query: 784 ASA 786
             A
Sbjct: 308 CVA 300

 Score = 37.4 bits (85), Expect = 0.022,   Method: Compositional matrix adjust.
 Identities = 27/102 (26%), Positives = 45/102 (44%), Gaps = 2/102 (1%)
 Frame = -3

Query: 696 ITAHEDRHIKFFDNKTGKMIHSMVAHLDAVTSLAVDPNGIYLMSGSHDCSIRLWNLDSKT 755
           ++   D+ ++ +D   GK       H   V S+A   +   ++SGS D +I+LWN  ++ 
Sbjct: 818 LSGSWDQTLRLWDLAAGKTTRRFEGHTKDVLSVAFSADNRQIVSGSRDKTIKLWNTLAEC 639

Query: 756 CVQEITAHRKKLDESIYDVAFHP--SKAYIASAGADALAKVF 795
              + T       + +  V F P  S   I S G D   KV+
Sbjct: 638 ---KFTIQEDGHTDWVSCVRFSPNHSNPIIVSCGWDRTVKVW 522

 Score = 36.2 bits (82), Expect = 0.046,   Method: Compositional matrix adjust.
 Identities = 28/118 (23%), Positives = 51/118 (43%), Gaps = 7/118 (5%)
 Frame = -3

Query: 685 RVVSHPTLPVTI-TAHEDRHIKFF------DNKTGKMIHSMVAHLDAVTSLAVDPNGIYL 737
           ++ ++P  P TI +A  D+ +  +      D   G     +  H   ++ + +  +G Y 
Sbjct: 998 QIATNPKDPDTIISASRDKTLIVWKLTRDEDTNYGYPQKRLYGHSHFISDVVLSSDGNYA 819

Query: 738 MSGSHDCSIRLWNLDSKTCVQEITAHRKKLDESIYDVAFHPSKAYIASAGADALAKVF 795
           +SGS D ++RLW+L +    +    H K     +  VAF      I S   D   K++
Sbjct: 818 LSGSWDQTLRLWDLAAGKTTRRFEGHTK----DVLSVAFSADNRQIVSGSRDKTIKLW 657
>03395
          Length = 2795

 Score = 48.1 bits (113), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 47/229 (20%), Positives = 93/229 (40%), Gaps = 12/229 (5%)
 Frame = +2

Query: 535 VLSLAISSNGEQCFSGGIDATIQWWNMPSPNVDPYDTYESNVLAGTLVAHTDAVWGLAYS 594
           V ++A++S G +  SGG +  ++ W++     D         L   +  H   V  +   
Sbjct: 5   VTAIAVTSCGTKLVSGGGEGQVRVWDIVK---DMLTGKTRGDLVANMKEHKGKVTAIQIH 175

Query: 595 GIKNQLLSCSADGTIRLW----NPQEKL-------PCVCTYNGDKEHGIPTSVDFIGCDP 643
                 +S S DG+  +W    N + ++        CVC + G   H + +  D      
Sbjct: 176 TNDRCCVSASTDGSTIIWDLITNTRSQIVLANTLFKCVC-FGGKDLHILTSGTD------ 334

Query: 644 AHMVTSFNTG-SAVIYDLETSQSLVMLSSQVDSGLQSSNHINRVVSHPTLPVTITAHEDR 702
            H +  +  G   ++ +LE SQ+  + +  +D   Q+                +T  ED 
Sbjct: 335 -HKIGYWEVGDGGLLRELEGSQTGAINTIDIDRDGQT---------------ILTGGEDS 466

Query: 703 HIKFFDNKTGKMIHSMVAHLDAVTSLAVDPNGIYLMSGSHDCSIRLWNL 751
            +K +    G++ H+ + H + +T   + PN  Y++SG  D ++ +W  
Sbjct: 467 LLKLWRYNEGEVTHTGIGHSNQITKARICPNRHYIVSGGEDGALHIWKF 613
>13278
          Length = 870

 Score = 47.8 bits (112), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 27/103 (26%), Positives = 53/103 (51%)
 Frame = +1

Query: 694 VTITAHEDRHIKFFDNKTGKMIHSMVAHLDAVTSLAVDPNGIYLMSGSHDCSIRLWNLDS 753
           +  +A  D  ++ ++ + G  +H++  H + V S+A  P+G YL SGS D  + +WN+ +
Sbjct: 118 ILASASFDSTVRLWEVERGLCLHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNVQT 297

Query: 754 KTCVQEITAHRKKLDESIYDVAFHPSKAYIASAGADALAKVFV 796
            + V     H  K    I++V ++     + ++ +D    VFV
Sbjct: 298 GSLV-----HSYKGTGGIFEVCWNHRGDKVGASASD--GSVFV 405
>13335
          Length = 863

 Score = 45.8 bits (107), Expect = 6e-05,   Method: Compositional matrix adjust.
 Identities = 38/141 (26%), Positives = 59/141 (41%), Gaps = 5/141 (3%)
 Frame = +1

Query: 478 HFDGVRALAFHPVEPVLVTASEDHTLKLWNLQKTVPAKKSASLDVEPIYTFRAHIGPVLS 537
           H D V ALA+ P    LV+ S +  L +W+         +  +D   +        P   
Sbjct: 184 HEDSVMALAYSPNGHYLVSGSPNGDLYVWDASFGHCRHLTLRVDAHDLGVTCCEFSPTFG 363

Query: 538 LAISSNGEQC----FSGGIDATIQWWNMPSPNVDPYDTYES-NVLAGTLVAHTDAVWGLA 592
            A + N   C     +GG D  I+ W   +    P  T +  ++L+G    H+D V   A
Sbjct: 364 TACAENSSTCNLLLATGGKDNLIKLWTFSAQVGSPEVTLQCRDILSG----HSDLVMACA 531

Query: 593 YSGIKNQLLSCSADGTIRLWN 613
           +S     L S S D ++RLW+
Sbjct: 532 FSPSSALLASGSFDKSVRLWD 594

 Score = 42.7 bits (99), Expect = 6e-04,   Method: Compositional matrix adjust.
 Identities = 31/118 (26%), Positives = 54/118 (45%), Gaps = 12/118 (10%)
 Frame = +1

Query: 690 PTLPVTITAHEDRHIKFFDNKTGKMIHSMVAHLDAVTSLAVDPNGIYLMSGSHDCSIRLW 749
           P+    ++  +D  I  ++  T K++ S V H D+V +LA  PNG YL+SGS +  + +W
Sbjct: 91  PSSSHLVSGSDDDTICMWEVATQKLVRSYVGHEDSVMALAYSPNGHYLVSGSPNGDLYVW 270

Query: 750 NLDSKTCVQEITAHRKKLDESIYDVAFHPS------------KAYIASAGADALAKVF 795
           +     C + +T      D  +    F P+               +A+ G D L K++
Sbjct: 271 DASFGHC-RHLTLRVDAHDLGVTCCEFSPTFGTACAENSSTCNLLLATGGKDNLIKLW 441

 Score = 35.8 bits (81), Expect = 0.063,   Method: Compositional matrix adjust.
 Identities = 54/224 (24%), Positives = 91/224 (40%), Gaps = 21/224 (9%)
 Frame = +1

Query: 549 SGGIDATIQWWNMPSPNVDPYDTYESNVLAGTLVAHTDAVWGLAYSGIKNQLLSCSADGT 608
           SG  D TI  W + +             L  + V H D+V  LAYS   + L+S S +G 
Sbjct: 112 SGSDDDTICMWEVATQK-----------LVRSYVGHEDSVMALAYSPNGHYLVSGSPNGD 258

Query: 609 IRLWNPQEKLPCVCTYNGDKEHGIPTSVDFIGCDPAHMVTSFNTGSA-------VIYDLE 661
           + +W+         ++   +   +      +G        +F T  A       ++    
Sbjct: 259 LYVWDA--------SFGHCRHLTLRVDAHDLGVTCCEFSPTFGTACAENSSTCNLLLATG 414

Query: 662 TSQSLVML---SSQVDS---GLQS----SNHINRVVS---HPTLPVTITAHEDRHIKFFD 708
              +L+ L   S+QV S    LQ     S H + V++    P+  +  +   D+ ++ +D
Sbjct: 415 GKDNLIKLWTFSAQVGSPEVTLQCRDILSGHSDLVMACAFSPSSALLASGSFDKSVRLWD 594

Query: 709 NKTGKMIHSMVA-HLDAVTSLAVDPNGIYLMSGSHDCSIRLWNL 751
           +  G  + S+ A H   VT  A   +G  L SGS D  I++W L
Sbjct: 595 SVKGVALFSIEACHSRFVTCCAFSIDGTLLASGSMDRIIKIWKL 726

 Score = 33.5 bits (75), Expect = 0.38,   Method: Compositional matrix adjust.
 Identities = 22/78 (28%), Positives = 34/78 (43%)
 Frame = +1

Query: 718 MVAHLDAVTSLAVDPNGIYLMSGSHDCSIRLWNLDSKTCVQEITAHRKKLDESIYDVAFH 777
           +  H D V + A  P+   L SGS D S+RLW+      +  I A   +    +   AF 
Sbjct: 496 LSGHSDLVMACAFSPSSALLASGSFDKSVRLWDSVKGVALFSIEACHSRF---VTCCAFS 666

Query: 778 PSKAYIASAGADALAKVF 795
                +AS   D + K++
Sbjct: 667 IDGTLLASGSMDRIIKIW 720
>19140
          Length = 573

 Score = 45.4 bits (106), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 24/80 (30%), Positives = 40/80 (50%)
 Frame = -3

Query: 710 KTGKMIHSMVAHLDAVTSLAVDPNGIYLMSGSHDCSIRLWNLDSKTCVQEITAHRKKLDE 769
           +T   +  +  H D V +L ++ +G   +SGS D +IRLW+L  + CV     H    DE
Sbjct: 523 RTCHKLMKLKGHTDNVKALVLNRDGTQCLSGSSDGTIRLWSLGQQRCVATFRVH----DE 356

Query: 770 SIYDVAFHPSKAYIASAGAD 789
            ++ +  + S   + S G D
Sbjct: 355 GVWALQANESFTTLYSGGRD 296

 Score = 37.7 bits (86), Expect = 0.018,   Method: Compositional matrix adjust.
 Identities = 39/167 (23%), Positives = 68/167 (40%), Gaps = 2/167 (1%)
 Frame = -3

Query: 475 LRSHFDGVRALAFHPVEPVLVTASEDHTLKLWNLQKTVPAKKSASLDVEPIYTFRAHIGP 534
           L+ H D V+AL  +      ++ S D T++LW+L +              + TFR H   
Sbjct: 499 LKGHTDNVKALVLNRDGTQCLSGSSDGTIRLWSLGQQ-----------RCVATFRVHDEG 353

Query: 535 VLSLAISSNGEQCFSGGIDATIQWWNMPSPNVDPYDTYESNVLAGTLVAHTD--AVWGLA 592
           V +L  + +    +SGG D  +   ++ +P+       E   +    +  TD  ++W   
Sbjct: 352 VWALQANESFTTLYSGGRDHQVWATDIKNPDNRELICEEKAPVLKLELTPTDPPSLWVAT 173

Query: 593 YSGIKNQLLSCSADGTIRLWNPQEKLPCVCTYNGDKEHGIPTSVDFI 639
                    SC  +  +RL NP+        Y+ D+ H   T  DF+
Sbjct: 172 TD-------SCIKNWPVRLPNPRASG----EYDNDRIHPTATQPDFV 65
>20662
          Length = 1220

 Score = 45.1 bits (105), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 26/73 (35%), Positives = 43/73 (58%), Gaps = 5/73 (6%)
 Frame = +2

Query: 447 TVTNDADYSYDLPANKDAFRKTWNPK----YTLRSHFDGVRALAFHPVEPVL-VTASEDH 501
           +V+ ++D S+ L A+ D   K WN      YT R+H D V  +  HP EP L ++ S+D 
Sbjct: 401 SVSINSDXSHYLSASYDHGIKVWNTDLTSLYTYRAHSDIVWDVQCHPTEPALFLSCSQDG 580

Query: 502 TLKLWNLQKTVPA 514
            + LW+++++ PA
Sbjct: 581 KIVLWDVRESKPA 619

 Score = 38.1 bits (87), Expect = 0.014,   Method: Compositional matrix adjust.
 Identities = 29/87 (33%), Positives = 39/87 (44%), Gaps = 1/87 (1%)
 Frame = +2

Query: 537 SLAISSNGEQCFSGGIDATIQWWNMPSPNVDPYDTYESNVLAGTLVAHTDAVWGLAYSGI 596
           S++I+S+     S   D  I+ WN      D    Y       T  AH+D VW +     
Sbjct: 401 SVSINSDXSHYLSASYDHGIKVWN-----TDLTSLY-------TYRAHSDIVWDVQCHPT 544

Query: 597 KNQL-LSCSADGTIRLWNPQEKLPCVC 622
           +  L LSCS DG I LW+ +E  P  C
Sbjct: 545 EPALFLSCSQDGKIVLWDVRESKPATC 625
>17602
          Length = 481

 Score = 44.7 bits (104), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 26/91 (28%), Positives = 48/91 (52%)
 Frame = +3

Query: 705 KFFDNKTGKMIHSMVAHLDAVTSLAVDPNGIYLMSGSHDCSIRLWNLDSKTCVQEITAHR 764
           + +D KTGK + ++ AH D VT++  + +G  ++S S+D   R+W+  S  C+  +    
Sbjct: 3   RIWDVKTGKCLKTLPAHSDPVTAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLXTLIDDD 182

Query: 765 KKLDESIYDVAFHPSKAYIASAGADALAKVF 795
              +  +  V F P+  YI +A  D   K++
Sbjct: 183 ---NPPVSFVKFSPNGKYILAATLDNTLKLW 266

 Score = 41.2 bits (95), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 24/111 (21%), Positives = 57/111 (51%), Gaps = 1/111 (0%)
 Frame = +3

Query: 657 IYDLETSQSLVMLSSQVDSGLQSSNHINRVVSHPTLPVTITAHEDRHIKFFDNKTGKMIH 716
           I+D++T + L  L +  D    ++ H NR  S     + +++  D   + +D  +G+ + 
Sbjct: 6   IWDVKTGKCLKTLPAHSDP--VTAVHFNRDGS-----LIVSSSYDGLCRIWDTASGQCLX 164

Query: 717 SMVAHLDA-VTSLAVDPNGIYLMSGSHDCSIRLWNLDSKTCVQEITAHRKK 766
           +++   +  V+ +   PNG Y+++ + D +++LW+     C++    HR +
Sbjct: 165 TLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYVGHRNE 317

 Score = 35.4 bits (80), Expect = 0.098,   Method: Compositional matrix adjust.
 Identities = 33/140 (23%), Positives = 59/140 (42%), Gaps = 4/140 (2%)
 Frame = +3

Query: 630 HGIPTSVDFIGCDPAHMVTSFNTGSAVIYDLETSQSLVMLSSQVDSGLQSSNHINRVVSH 689
           H  P +      D + +V+S   G   I+D  + Q L  L   +D     +  ++ V   
Sbjct: 51  HSDPVTAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLXTL---ID---DDNPPVSFVKFS 212

Query: 690 PTLPVTITAHEDRHIKFFDNKTGKMIHSMVAHLDAVTSLAVD---PNGIYLMSGSHDCSI 746
           P     + A  D  +K +D   GK + + V H +    +  +     G +++SGS D  +
Sbjct: 213 PNGKYILAATLDNTLKLWDYSKGKCLKTYVGHRNEKYCIFANFSVTGGKWIVSGSEDNMV 392

Query: 747 RLWN-LDSKTCVQEITAHRK 765
            +WN LD     +   +HR+
Sbjct: 393 YIWNLLDQGDSTEATGSHRR 452
>00825
          Length = 1821

 Score = 43.9 bits (102), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 75/305 (24%), Positives = 127/305 (41%), Gaps = 9/305 (2%)
 Frame = -2

Query: 500  DHTLKLWNLQKTVPAKKSASLDVEPIYTFRAHIGPVLSLAISSNGEQCFSGGIDATIQWW 559
            D  L  WNL K   A +            +AH G V  +A  S+G+  FS G D TI+ W
Sbjct: 1808 DGELICWNLPKQQMACR-----------VQAHDGIVHGMAAHSSGQYFFSCGSDKTIKQW 1662

Query: 560  NM-PSPNVDPYDTYESNVLAGTLVAHTDAVWGLAYSGIKNQLLSCSADGTIRLWNPQEKL 618
            ++ P   + P     + +LA  +    D  W       K+ +   S    + +W+ +   
Sbjct: 1661 SLDPEGTIAPEPV--NTLLAKCIYTSLDHHW-------KDDIFVTSG-SRVDVWDEKRSE 1512

Query: 619  PCVCTYNGDKEHGIPTSVDFIGCDPAHMVTSFNTGSA------VIYDLETSQSLVMLSSQ 672
            P      G +      SV  +  +P   V ++  G+A      ++YD+  S  L  +  +
Sbjct: 1511 PMRSFSWGVE------SVHHVKFNP---VETYLLGAAAHDRSILLYDMRGSAPLRKVVMK 1359

Query: 673  VDSGLQSSNHINRVVSHPTLPVTIT-AHEDRHIKFFDNKTGKMIHSMVA-HLDAVTSLAV 730
            + +   S N        P    TIT A+ED ++  FD +   M  +M   H  AV  +  
Sbjct: 1358 MRTNALSWN--------PMEAFTITSANEDGNLYTFDMRKLSMPLNMHRDHTAAVMDVDY 1203

Query: 731  DPNGIYLMSGSHDCSIRLWNLDSKTCVQEITAHRKKLDESIYDVAFHPSKAYIASAGADA 790
             P G   +S  +D  IR++ +D K   +E+  H K++ + +  V +     YI SA  + 
Sbjct: 1202 CPTGREFVSAGYDKVIRIFPVD-KGHSREVY-HTKRM-QRVGSVVWSRDSKYIFSASDEM 1032

Query: 791  LAKVF 795
              +V+
Sbjct: 1031 NIRVW 1017
>19498
          Length = 903

 Score = 43.9 bits (102), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 38/117 (32%), Positives = 51/117 (43%), Gaps = 8/117 (6%)
 Frame = -1

Query: 505 LWNLQKTVPAKKSASLDVEPIYT-FRAHIGPVLSLAISSNGEQCFSGGIDATIQWWNMPS 563
           +WN+      K+ A  DV  +     +H+G V  +  S NG+   SGG D  I  W + S
Sbjct: 870 IWNMAPIRDEKEEADDDVPRVLCQMDSHLGCVNCVRWSENGKFLASGGDDKLIMIWQI-S 694

Query: 564 PNVDPYDTYESNVL-------AGTLVAHTDAVWGLAYSGIKNQLLSCSADGTIRLWN 613
                  ++ SNV          TL  H   V  LA+S     L SCS D TI +WN
Sbjct: 693 RGFGSGKSFGSNVTILEHWRSVATLRGHAGDVLDLAWSPQDLWLASCSVDNTIVVWN 523

 Score = 35.0 bits (79), Expect = 0.13,   Method: Compositional matrix adjust.
 Identities = 46/185 (24%), Positives = 66/185 (35%), Gaps = 2/185 (1%)
 Frame = -1

Query: 469 WNPKYTLRSHFDGVRALAFHPVEPVLVTASEDHTLKLWNLQKTVPAKKSASLDVEPIYTF 528
           W    TLR H   V  LA+ P +  L + S D+T+ +WN  K            E +   
Sbjct: 639 WRSVATLRGHAGDVLDLAWSPQDLWLASCSVDNTIVVWNALKF----------SEQVAVI 490

Query: 529 RAHIGPVLSLAISSNGEQCFSGGIDATIQWWNMPSPNVDPYDTYESNVLAGTL--VAHTD 586
           R H G V  +     G    S   D T++ W          D  E   +         T 
Sbjct: 489 RGHAGMVKGVTWDPVGRYLASQSDDKTLRVWRTS-------DWKEETCVKSCFKECGGTT 331

Query: 587 AVWGLAYSGIKNQLLSCSADGTIRLWNPQEKLPCVCTYNGDKEHGIPTSVDFIGCDPAHM 646
            V  L +S   N ++S  A        P  ++         + +G  TS+DF+G   A  
Sbjct: 330 HVLRLNWSPDGNHVVSAHAMNNA---XPTAQII--------ERNGWGTSLDFVGHRKAIT 184

Query: 647 VTSFN 651
           V  FN
Sbjct: 183 VVRFN 169

 Score = 28.9 bits (63), Expect = 9.6,   Method: Compositional matrix adjust.
 Identities = 23/101 (22%), Positives = 41/101 (40%), Gaps = 13/101 (12%)
 Frame = -1

Query: 708 DNKTGKMIHSMVAHLDAVTSLAVDPNGIYLMSGSHDCSIRLWNL-----DSKTCVQEIT- 761
           D+   +++  M +HL  V  +    NG +L SG  D  I +W +       K+    +T 
Sbjct: 828 DDDVPRVLCQMDSHLGCVNCVRWSENGKFLASGGDDKLIMIWQISRGFGSGKSFGSNVTI 649

Query: 762 -------AHRKKLDESIYDVAFHPSKAYIASAGADALAKVF 795
                  A  +     + D+A+ P   ++AS   D    V+
Sbjct: 648 LEHWRSVATLRGHAGDVLDLAWSPQDLWLASCSVDNTIVVW 526
>21763
          Length = 923

 Score = 43.9 bits (102), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 30/113 (26%), Positives = 53/113 (46%)
 Frame = +1

Query: 678 QSSNHINRVVSHPTLPVTITAHEDRHIKFFDNKTGKMIHSMVAHLDAVTSLAVDPNGIYL 737
           QS   I  V  HP  P+   A   R ++ ++  T + +  +  +   ++S+ V P G  +
Sbjct: 313 QSKGLIQCVKFHPLRPIFFVA-SQRFVRIYNLLTQQFVKKLQTNCKWISSMDVHPGGDNV 489

Query: 738 MSGSHDCSIRLWNLDSKTCVQEITAHRKKLDESIYDVAFHPSKAYIASAGADA 790
           + GS+DC    ++LD  T   +I  H K+   ++  V++H      ASA  D 
Sbjct: 490 IIGSYDCKSCWFDLDLSTKPYKILRHHKR---AVRHVSYHHRYPLFASASDDG 639
>37180
          Length = 681

 Score = 43.5 bits (101), Expect = 3e-04,   Method: Composition-based stats.
 Identities = 28/80 (35%), Positives = 45/80 (56%), Gaps = 3/80 (3%)
 Frame = +1

Query: 488 HPVEPVLVTASEDHTLKLWNLQKTVPAKKSASLDVEPIYTFRAHIGPVLSLAISSNGEQC 547
           HP + ++VT+S+D T +LW+       + SA L    +  F+ H  PV S A+ ++G++ 
Sbjct: 46  HPTQRLVVTSSKDMTFRLWDF------RDSALL----VNVFQGHTQPVTS-AVFASGDKV 192

Query: 548 FSGGIDATIQWW---NMPSP 564
            SG  D T++ W   NM SP
Sbjct: 193 VSGSDDRTVRVWDMRNMRSP 252

 Score = 35.4 bits (80), Expect = 0.099,   Method: Composition-based stats.
 Identities = 20/70 (28%), Positives = 42/70 (60%), Gaps = 1/70 (1%)
 Frame = +1

Query: 683 INRVVSHPTLPVTITAHEDRHIKFFDNK-TGKMIHSMVAHLDAVTSLAVDPNGIYLMSGS 741
           ++ V +HPT  + +T+ +D   + +D + +  +++    H   VTS AV  +G  ++SGS
Sbjct: 28  LSDVHAHPTQRLVVTSSKDMTFRLWDFRDSALLVNVFQGHTQPVTS-AVFASGDKVVSGS 204

Query: 742 HDCSIRLWNL 751
            D ++R+W++
Sbjct: 205 DDRTVRVWDM 234
>11915
          Length = 737

 Score = 43.5 bits (101), Expect = 4e-04,   Method: Composition-based stats.
 Identities = 30/98 (30%), Positives = 49/98 (50%), Gaps = 3/98 (3%)
 Frame = +1

Query: 694 VTITAHEDRHIKFFDNKTGKMIHSMVAHLDAVTSL--AVDPNGIYLMSGSHDCSIRLWNL 751
           V  T H    IK ++ +TGK++  M+ H   V  L  A D N + LMS SHD +++LW  
Sbjct: 448 VLATGHVSGRIKLWNCETGKLLIEMMDHKATVHDLHFAAD-NSLCLMSASHDGTVKLWEF 624

Query: 752 DSK-TCVQEITAHRKKLDESIYDVAFHPSKAYIASAGA 788
           D +  C   +T       +  +   +   + Y+A+AG+
Sbjct: 625 DDQGDCNMYLTLRTNA--KHAFSCRWSHDRRYVATAGS 732
>02948
          Length = 1207

 Score = 43.1 bits (100), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 30/120 (25%), Positives = 51/120 (42%), Gaps = 2/120 (1%)
 Frame = -2

Query: 678 QSSNHINRVVSHPTLPVTITAHEDRHIKFFDNKTGKMIHSMVAHLDA--VTSLAVDPNGI 735
           Q++     V  HPT     T H    I F+ N         V+H  +  VT LA  P G 
Sbjct: 762 QNNAAFTCVSCHPTDVCIATGHASGKITFWWNFDQDKTVLSVSHWHSLPVTCLAFTPEGS 583

Query: 736 YLMSGSHDCSIRLWNLDSKTCVQEITAHRKKLDESIYDVAFHPSKAYIASAGADALAKVF 795
            L+SG H+C++  W ++S     E      +L   ++++   P   +  +  +D + +V 
Sbjct: 582 CLLSGGHECTLVRWQMNS-----EHKEFLPRLGAPLHNIVVSPDGVFFVTGHSDNVLQVI 418
>26939
          Length = 388

 Score = 43.1 bits (100), Expect = 5e-04,   Method: Composition-based stats.
 Identities = 21/62 (33%), Positives = 34/62 (54%)
 Frame = +2

Query: 734 GIYLMSGSHDCSIRLWNLDSKTCVQEITAHRKKLDESIYDVAFHPSKAYIASAGADALAK 793
           G YL+S S D +IR+W+L +K C++ + AH+         + FH +  Y+ S   D   K
Sbjct: 2   GKYLVSASDDKTIRVWDLRNKRCMKTLYAHQ----HFCTSIDFHKAHPYVISGSVDQTVK 169

Query: 794 VF 795
           V+
Sbjct: 170 VW 175

 Score = 33.5 bits (75), Expect = 0.31,   Method: Composition-based stats.
 Identities = 14/54 (25%), Positives = 32/54 (59%)
 Frame = +2

Query: 696 ITAHEDRHIKFFDNKTGKMIHSMVAHLDAVTSLAVDPNGIYLMSGSHDCSIRLW 749
           ++A +D+ I+ +D +  + + ++ AH    TS+       Y++SGS D ++++W
Sbjct: 14  VSASDDKTIRVWDLRNKRCMKTLYAHQHFCTSIDFHKAHPYVISGSVDQTVKVW 175

 Score = 30.4 bits (67), Expect = 3.2,   Method: Composition-based stats.
 Identities = 15/56 (26%), Positives = 28/56 (50%), Gaps = 5/56 (8%)
 Frame = +2

Query: 456 YDLPANKDAFRKTWNPK-----YTLRSHFDGVRALAFHPVEPVLVTASEDHTLKLW 506
           Y + A+ D   + W+ +      TL +H     ++ FH   P +++ S D T+K+W
Sbjct: 8   YLVSASDDKTIRVWDLRNKRCMKTLYAHQHFCTSIDFHKAHPYVISGSVDQTVKVW 175
>30176
          Length = 365

 Score = 41.6 bits (96), Expect = 0.001,   Method: Composition-based stats.
 Identities = 24/63 (38%), Positives = 29/63 (46%), Gaps = 16/63 (25%)
 Frame = +2

Query: 580 TLVAHTDAVWGLAYSGIKNQLLSCSADGTIRLWNPQEKLP----------------CVCT 623
           TL +HT  VW L +     +L SCS D TI++W  QE LP                CVCT
Sbjct: 5   TLKSHTSTVWNLTFDKTGTRLASCSDDKTIKIW--QEYLPGNPEGIVTKDNEPTWKCVCT 178

Query: 624 YNG 626
             G
Sbjct: 179 LGG 187

 Score = 29.6 bits (65), Expect = 4.9,   Method: Composition-based stats.
 Identities = 21/69 (30%), Positives = 32/69 (46%), Gaps = 2/69 (2%)
 Frame = +2

Query: 474 TLRSHFDGVRALAFHPVEPVLVTASEDHTLKLWNLQKTVPAKKSA--SLDVEPIYTFRAH 531
           TL+SH   V  L F      L + S+D T+K+W  Q+ +P       + D EP +     
Sbjct: 5   TLKSHTSTVWNLTFDKTGTRLASCSDDKTIKIW--QEYLPGNPEGIVTKDNEPTWKCVCT 178

Query: 532 IGPVLSLAI 540
           +G   S A+
Sbjct: 179 LGGYTSRAL 205
>15118
          Length = 1074

 Score = 41.6 bits (96), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 20/75 (26%), Positives = 40/75 (53%)
 Frame = +3

Query: 677 LQSSNHINRVVSHPTLPVTITAHEDRHIKFFDNKTGKMIHSMVAHLDAVTSLAVDPNGIY 736
           L+ S  I+R++ H    +     ED  +   D  T +++     H +++T L+   +G +
Sbjct: 318 LKMSEGISRILLHRDSNMLAVVLEDFTVSVIDVDTLRVVRVFSGHSNSITDLSFSGDGRW 497

Query: 737 LMSGSHDCSIRLWNL 751
           L++ S DC++R W+L
Sbjct: 498 LITASMDCTVRTWSL 542

 Score = 33.9 bits (76), Expect = 0.25,   Method: Compositional matrix adjust.
 Identities = 25/119 (21%), Positives = 44/119 (36%), Gaps = 34/119 (28%)
 Frame = +3

Query: 477 SHFDGVRALAFHPVEPVLVTASEDHTLKLW------------------------------ 506
           +H  GVR +AF     +L+TA  D  +K W                              
Sbjct: 186 AHVSGVRGVAFDAFNCLLITAGGDCDIKFWRFGSRDRARVLLKELKMSEGISRILLHRDS 365

Query: 507 NLQKTVPAKKSAS-LDVEP---IYTFRAHIGPVLSLAISSNGEQCFSGGIDATIQWWNM 561
           N+   V    + S +DV+    +  F  H   +  L+ S +G    +  +D T++ W++
Sbjct: 366 NMLAVVLEDFTVSVIDVDTLRVVRVFSGHSNSITDLSFSGDGRWLITASMDCTVRTWSL 542

 Score = 33.1 bits (74), Expect = 0.43,   Method: Compositional matrix adjust.
 Identities = 21/85 (24%), Positives = 36/85 (42%), Gaps = 3/85 (3%)
 Frame = +3

Query: 703 HIKFFDNKTGKMIHSM---VAHLDAVTSLAVDPNGIYLMSGSHDCSIRLWNLDSKTCVQE 759
           H+  ++ ++GK   S    VAH+  V  +A D     L++   DC I+ W   S+     
Sbjct: 126 HLDIYNLQSGKHRGSFGDTVAHVSGVRGVAFDAFNCLLITAGGDCDIKFWRFGSRD-RAR 302

Query: 760 ITAHRKKLDESIYDVAFHPSKAYIA 784
           +     K+ E I  +  H     +A
Sbjct: 303 VLLKELKMSEGISRILLHRDSNMLA 377
>15780
          Length = 735

 Score = 41.6 bits (96), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 21/55 (38%), Positives = 29/55 (52%)
 Frame = -1

Query: 697 TAHEDRHIKFFDNKTGKMIHSMVAHLDAVTSLAVDPNGIYLMSGSHDCSIRLWNL 751
           TA  D  +  +D  +G  +  + AH D V +L    +G  L SG  D SIRLW+L
Sbjct: 723 TAGADHTVIVWDIASGTAVAHLTAHTDTVYALCFSRDGTVLASGGMDNSIRLWDL 559

 Score = 39.3 bits (90), Expect = 0.006,   Method: Composition-based stats.
 Identities = 34/122 (27%), Positives = 54/122 (44%), Gaps = 12/122 (9%)
 Frame = -1

Query: 494 LVTASEDHTLKLWNLQKTVPAKKSASLDVEPIYTFRAHIGPVLSLAISSNGEQCFSGGID 553
           L TA  DHT+ +W++     A  +A      +    AH   V +L  S +G    SGG+D
Sbjct: 729 LSTAGADHTVIVWDI-----ASGTA------VAHLTAHTDTVYALCFSRDGTVLASGGMD 583

Query: 554 ATIQWWNMPSPNVDPYDTYESNV------------LAGTLVAHTDAVWGLAYSGIKNQLL 601
            +I+ W++     +     +SNV            L GT    +  V+GL ++  +N LL
Sbjct: 582 NSIRLWDLARVMEEQDPETDSNVPSSLSVNTNPALLLGTYYTKSSPVFGLHFTR-RNVLL 406

Query: 602 SC 603
            C
Sbjct: 405 GC 400

 Score = 38.5 bits (88), Expect = 0.012,   Method: Compositional matrix adjust.
 Identities = 31/125 (24%), Positives = 59/125 (47%), Gaps = 4/125 (3%)
 Frame = -1

Query: 549 SGGIDATIQWWNMPSPNVDPYDTYESNVLAGTLVAHTDAVWGLAYSGIKNQLLSCSADGT 608
           + G D T+  W++ S     +           L AHTD V+ L +S     L S   D +
Sbjct: 723 TAGADHTVIVWDIASGTAVAH-----------LTAHTDTVYALCFSRDGTVLASGGMDNS 577

Query: 609 IRLWN----PQEKLPCVCTYNGDKEHGIPTSVDFIGCDPAHMVTSFNTGSAVIYDLETSQ 664
           IRLW+     +E+ P       + +  +P+S+  +  +PA ++ ++ T S+ ++ L  ++
Sbjct: 576 IRLWDLARVMEEQDP-------ETDSNVPSSLS-VNTNPALLLGTYYTKSSPVFGLHFTR 421

Query: 665 SLVML 669
             V+L
Sbjct: 420 RNVLL 406

 Score = 32.3 bits (72), Expect = 0.83,   Method: Compositional matrix adjust.
 Identities = 16/54 (29%), Positives = 28/54 (51%)
 Frame = -1

Query: 736 YLMSGSHDCSIRLWNLDSKTCVQEITAHRKKLDESIYDVAFHPSKAYIASAGAD 789
           YL +   D ++ +W++ S T V  +TAH     +++Y + F      +AS G D
Sbjct: 732 YLSTAGADHTVIVWDIASGTAVAHLTAHT----DTVYALCFSRDGTVLASGGMD 583
>27465
          Length = 658

 Score = 41.6 bits (96), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 31/143 (21%), Positives = 60/143 (41%), Gaps = 1/143 (0%)
 Frame = -1

Query: 475 LRSHFDGVRALAFHPVEPVLVTASEDHTLKLWNLQKTVPAKKSASLDVEPIYTFRAHIGP 534
           LR+H   +  +AF+      +T S D T K+W+           +   E ++T   H   
Sbjct: 373 LRAHILPLTNVAFNKSGSSFITGSYDRTCKIWD-----------TASAEELHTLEGHRNV 227

Query: 535 VLSLAISS-NGEQCFSGGIDATIQWWNMPSPNVDPYDTYESNVLAGTLVAHTDAVWGLAY 593
           V ++A ++  G++  +G  D T + W+                   TL  HT  +  +++
Sbjct: 226 VYAIAFNNPFGDKVITGSFDKTCKLWSTADGKC-----------YHTLRGHTAEIVCVSF 80

Query: 594 SGIKNQLLSCSADGTIRLWNPQE 616
           +     + + S D T RLW+ ++
Sbjct: 79  NPSSTLIATGSMDTTCRLWDVEK 11

 Score = 33.5 bits (75), Expect = 0.30,   Method: Compositional matrix adjust.
 Identities = 13/38 (34%), Positives = 24/38 (63%)
 Frame = -1

Query: 473 YTLRSHFDGVRALAFHPVEPVLVTASEDHTLKLWNLQK 510
           +TLR H   +  ++F+P   ++ T S D T +LW+++K
Sbjct: 124 HTLRGHTAEIVCVSFNPSSTLIATGSMDTTCRLWDVEK 11

 Score = 31.6 bits (70), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 18/83 (21%), Positives = 42/83 (50%), Gaps = 1/83 (1%)
 Frame = -1

Query: 714 MIHSMVAHLDAVTSLAVDPNGIYLMSGSHDCSIRLWNLDSKTCVQEITAHRKKLDESIYD 773
           +   + AH+  +T++A + +G   ++GS+D + ++W+  S   +  +  HR      +Y 
Sbjct: 385 LFKVLRAHILPLTNVAFNKSGSSFITGSYDRTCKIWDTASAEELHTLEGHR----NVVYA 218

Query: 774 VAF-HPSKAYIASAGADALAKVF 795
           +AF +P    + +   D   K++
Sbjct: 217 IAFNNPFGDKVITGSFDKTCKLW 149
>21921
          Length = 1341

 Score = 40.4 bits (93), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 20/69 (28%), Positives = 35/69 (50%)
 Frame = -1

Query: 720 AHLDAVTSLAVDPNGIYLMSGSHDCSIRLWNLDSKTCVQEITAHRKKLDESIYDVAFHPS 779
            H   V S+  DP G +L+SGS D +IR W + S  C++ +     ++   +  VA++P+
Sbjct: 489 GHTGIVRSICPDPTGQWLVSGSDDGTIRFWEVSSGRCMKTL-----QVGGCVTSVAWNPN 325

Query: 780 KAYIASAGA 788
            +    A  
Sbjct: 324 PSLCVVAAT 298
>01249
          Length = 1743

 Score = 40.0 bits (92), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 42/185 (22%), Positives = 64/185 (34%), Gaps = 46/185 (24%)
 Frame = -1

Query: 475  LRSHFDGVRALAFHPVEPVLVTASEDHTLKLWNLQKTVPAKKSASLDVEPIYTFRAHIGP 534
            L S F+    + F       V A+    L +W+  + V      +  ++P  T  AH  P
Sbjct: 1383 LLSDFNEATKIQFTDDGSQFVVATSSGHLNIWDFARVVTTTSQRARGLKPGRTINAHSEP 1204

Query: 535  VLSLAISSNG--EQCFSGGIDATIQWWNMPSPNVDPYDTYESNV------------LAG- 579
            +  L +   G   +  S   D T + W+M S  +     YE+ V            LAG 
Sbjct: 1203 ITGLHVGCGGPAARVASSSSDGTCKLWDMLSGALLRTMVYETGVGCLIMDKQEHFLLAGL 1024

Query: 580  -------------------------------TLVAHTDAVWGLAYSGIKNQLLSCSADGT 608
                                            L  H+DAV  LA+S    +L S S +G 
Sbjct: 1023 DNGDILCSPLFGQISQSEVFVSKHTTKAGERVLQGHSDAVTCLAFSSDGQRLASGSQNGK 844

Query: 609  IRLWN 613
            + +WN
Sbjct: 843  VIIWN 829

 Score = 33.1 bits (74), Expect = 0.43,   Method: Compositional matrix adjust.
 Identities = 15/34 (44%), Positives = 21/34 (61%)
 Frame = -1

Query: 720 AHLDAVTSLAVDPNGIYLMSGSHDCSIRLWNLDS 753
            H DAVT LA   +G  L SGS +  + +WN++S
Sbjct: 921 GHSDAVTCLAFSSDGQRLASGSQNGKVIIWNMES 820
>12960
          Length = 550

 Score = 40.0 bits (92), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 38/167 (22%), Positives = 64/167 (38%)
 Frame = +2

Query: 451 DADYSYDLPANKDAFRKTWNPKYTLRSHFDGVRALAFHPVEPVLVTASEDHTLKLWNLQK 510
           + +  ++LP  K+          T+      VRA+ F       +T   D ++KLWN  +
Sbjct: 116 NTNMKFELPDRKEV---------TINCKQQAVRAVRFSVDSRYCMTCGSDKSVKLWNPHR 268

Query: 511 TVPAKKSASLDVEPIYTFRAHIGPVLSLAISSNGEQCFSGGIDATIQWWNMPSPNVDPYD 570
            +  K           T+  H   VL    S +  Q  SGGID T+  +++ S       
Sbjct: 269 ELFLK-----------TYIGHGHEVLDAQGSGDNSQICSGGIDKTVVLFDVASGQ--ALR 409

Query: 571 TYESNVLAGTLVAHTDAVWGLAYSGIKNQLLSCSADGTIRLWNPQEK 617
            Y           H   V  + ++     +LS S D T+R W+ + +
Sbjct: 410 KYRD---------HAGTVNCVKFNEESTVILSGSLDNTVRAWDTRSR 523

 Score = 30.4 bits (67), Expect = 2.7,   Method: Compositional matrix adjust.
 Identities = 13/55 (23%), Positives = 27/55 (49%)
 Frame = +2

Query: 701 DRHIKFFDNKTGKMIHSMVAHLDAVTSLAVDPNGIYLMSGSHDCSIRLWNLDSKT 755
           D+ +  FD  +G+ +     H   V  +  +     ++SGS D ++R W+  S++
Sbjct: 362 DKTVVLFDVASGQALRKYRDHAGTVNCVKFNEESTVILSGSLDNTVRAWDTRSRS 526

 Score = 29.6 bits (65), Expect = 4.8,   Method: Compositional matrix adjust.
 Identities = 23/88 (26%), Positives = 44/88 (50%), Gaps = 1/88 (1%)
 Frame = +2

Query: 580 TLVAHTDAVWGLAYSGIKNQLLSCSADGTIRLWNPQEKLPCVCTYNGDKEHGIPTSVDFI 639
           T+     AV  + +S      ++C +D +++LWNP  +L  + TY G   HG    +D  
Sbjct: 158 TINCKQQAVRAVRFSVDSRYCMTCGSDKSVKLWNPHRELF-LKTYIG---HGHEV-LDAQ 322

Query: 640 GC-DPAHMVTSFNTGSAVIYDLETSQSL 666
           G  D + + +     + V++D+ + Q+L
Sbjct: 323 GSGDNSQICSGGIDKTVVLFDVASGQAL 406
>18981
          Length = 407

 Score = 39.7 bits (91), Expect = 0.005,   Method: Composition-based stats.
 Identities = 21/82 (25%), Positives = 43/82 (52%)
 Frame = -2

Query: 696 ITAHEDRHIKFFDNKTGKMIHSMVAHLDAVTSLAVDPNGIYLMSGSHDCSIRLWNLDSKT 755
           ++   D+ +  ++  TG+ +H +  H +A+T++  D      +SGS D  +R W LD+  
Sbjct: 256 VSGSWDKTLIVWEVDTGRPVHQLHGHTEAITAVQFDEGKA--VSGSADGDVRTWALDTGQ 83

Query: 756 CVQEITAHRKKLDESIYDVAFH 777
           C+  +T  +   D  +Y V ++
Sbjct: 82  CLLTMTTGQ---DIEVYCVVYN 26
>15337
          Length = 860

 Score = 39.3 bits (90), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 15/75 (20%), Positives = 39/75 (52%)
 Frame = -1

Query: 700 EDRHIKFFDNKTGKMIHSMVAHLDAVTSLAVDPNGIYLMSGSHDCSIRLWNLDSKTCVQE 759
           +D H++ F+  + ++I +M ++   +  +   P+G Y+++G  D  + +W+   K  V  
Sbjct: 269 QDGHLRVFNYNSMELIGTMKSYFGGLLCVCWSPDGKYIVTGGEDDLVTVWSFHEKRVVCR 90

Query: 760 ITAHRKKLDESIYDV 774
              H+  ++   +D+
Sbjct: 89  GHGHKSWVNVVAFDI 45
>15972
          Length = 1069

 Score = 38.9 bits (89), Expect = 0.009,   Method: Compositional matrix adjust.
 Identities = 17/37 (45%), Positives = 22/37 (59%)
 Frame = +3

Query: 471 PKYTLRSHFDGVRALAFHPVEPVLVTASEDHTLKLWN 507
           P+ T   H   VR LA HP   + +T S+D TL+LWN
Sbjct: 213 PERTFSGHKGPVRHLAVHPSGKLTLTVSQDRTLRLWN 323

 Score = 31.6 bits (70), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 14/37 (37%), Positives = 20/37 (54%)
 Frame = +3

Query: 524 PIYTFRAHIGPVLSLAISSNGEQCFSGGIDATIQWWN 560
           P  TF  H GPV  LA+  +G+   +   D T++ WN
Sbjct: 213 PERTFSGHKGPVRHLAVHPSGKLTLTVSQDRTLRLWN 323

 Score = 30.8 bits (68), Expect = 2.4,   Method: Compositional matrix adjust.
 Identities = 18/81 (22%), Positives = 47/81 (58%), Gaps = 3/81 (3%)
 Frame = +3

Query: 683 INRVVSHPTLPVTITAHEDRHIKFFDNKTGKMIHSMVAHL-DAVTSLAVDPNGIYLMSG- 740
           +  +  HP+  +T+T  +DR ++ ++N  G++  + ++++ +A  S+   P G+Y +   
Sbjct: 246 VRHLAVHPSGKLTLTVSQDRTLRLWNNMNGRI--AFISNMKEAAESVRWAPGGLYYVVAF 419

Query: 741 -SHDCSIRLWNLDSKTCVQEI 760
            SH   + +++++SK  ++ I
Sbjct: 420 RSH---LDVYSVESKGLLRSI 473
>11493
          Length = 535

 Score = 37.0 bits (84), Expect = 0.035,   Method: Composition-based stats.
 Identities = 29/129 (22%), Positives = 48/129 (37%)
 Frame = -2

Query: 482 VRALAFHPVEPVLVTASEDHTLKLWNLQKTVPAKKSASLDVEPIYTFRAHIGPVLSLAIS 541
           +R++   P    L+   E   L +W+L    P  K+      P            +LAIS
Sbjct: 330 IRSVKLLPDGRTLIVGGEASNLSIWDLASPTPRIKAELTSAAP---------ACYALAIS 178

Query: 542 SNGEQCFSGGIDATIQWWNMPSPNVDPYDTYESNVLAGTLVAHTDAVWGLAYSGIKNQLL 601
            + + CFS   D  I  W++            + +L      HTD    +  S   ++L 
Sbjct: 177 PDSKVCFSCCSDGNIAVWDL-----------HNEILVRQFQGHTDGASCIDISPDGSRLW 31

Query: 602 SCSADGTIR 610
           +   D T+R
Sbjct: 30  TGGLDNTVR 4

 Score = 30.4 bits (67), Expect = 3.2,   Method: Composition-based stats.
 Identities = 18/79 (22%), Positives = 33/79 (41%)
 Frame = -2

Query: 535 VLSLAISSNGEQCFSGGIDATIQWWNMPSPNVDPYDTYESNVLAGTLVAHTDAVWGLAYS 594
           + S+ +  +G     GG  + +  W++ SP         +  +   L +   A + LA S
Sbjct: 330 IRSVKLLPDGRTLIVGGEASNLSIWDLASP---------TPRIKAELTSAAPACYALAIS 178

Query: 595 GIKNQLLSCSADGTIRLWN 613
                  SC +DG I +W+
Sbjct: 177 PDSKVCFSCCSDGNIAVWD 121
>38039
          Length = 816

 Score = 36.6 bits (83), Expect = 0.037,   Method: Compositional matrix adjust.
 Identities = 20/55 (36%), Positives = 25/55 (45%)
 Frame = -1

Query: 584 HTDAVWGLAYSGIKNQLLSCSADGTIRLWNPQEKLPCVCTYNGDKEHGIPTSVDF 638
           H D + GL          S S DGTIR+WN + +L  V   N      IP S+ F
Sbjct: 510 HVDLITGLTSCSRMKLFASSSMDGTIRVWNEENRLVRVLRLN-----AIPNSIGF 361
>02090
          Length = 1841

 Score = 36.6 bits (83), Expect = 0.042,   Method: Compositional matrix adjust.
 Identities = 19/95 (20%), Positives = 40/95 (42%)
 Frame = -3

Query: 690  PTLPVTITAHEDRHIKFFDNKTGKMIHSMVAHLDAVTSLAVDPNGIYLMSGSHDCSIRLW 749
            P   V  +   D +I  +D     ++     H D  + + + P+G  L +G  D ++R W
Sbjct: 1596 PDGKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISPDGTKLWTGGLDNTVRSW 1417

Query: 750  NLDSKTCVQEITAHRKKLDESIYDVAFHPSKAYIA 784
            +L     +Q+           I+ + + P+  ++A
Sbjct: 1416 DLREGRQLQQ-----HDFSSQIFSLGYCPTGEWLA 1327

 Score = 35.0 bits (79), Expect = 0.13,   Method: Compositional matrix adjust.
 Identities = 21/90 (23%), Positives = 38/90 (42%)
 Frame = -3

Query: 472  KYTLRSHFDGVRALAFHPVEPVLVTASEDHTLKLWNLQKTVPAKKSASLDVEPIYTFRAH 531
            K  L S      ALA  P   V  +   D  + +W+L      ++           F+ H
Sbjct: 1647 KAELTSSAPACYALAISPDGKVCFSCCSDGNIAVWDLHNQTLVRQ-----------FQGH 1501

Query: 532  IGPVLSLAISSNGEQCFSGGIDATIQWWNM 561
                  + IS +G + ++GG+D T++ W++
Sbjct: 1500 TDGASCIDISPDGTKLWTGGLDNTVRSWDL 1411

 Score = 30.0 bits (66), Expect = 3.7,   Method: Compositional matrix adjust.
 Identities = 13/40 (32%), Positives = 23/40 (57%)
 Frame = -3

Query: 724  AVTSLAVDPNGIYLMSGSHDCSIRLWNLDSKTCVQEITAH 763
            A  +LA+ P+G    S   D +I +W+L ++T V++   H
Sbjct: 1620 ACYALAISPDGKVCFSCCSDGNIAVWDLHNQTLVRQFQGH 1501
>39204
          Length = 1684

 Score = 36.6 bits (83), Expect = 0.045,   Method: Compositional matrix adjust.
 Identities = 33/127 (25%), Positives = 51/127 (40%), Gaps = 7/127 (5%)
 Frame = -2

Query: 478  HFDGVRALAFHPVE------PVLVTASEDHTLKLWNL-QKTVPAKKSASLDVEPIYTFRA 530
            H+  VR L F PV       P+LV+A +D   KLW L  +T   K       E +  +R 
Sbjct: 1272 HYKAVRCLRFKPVTDSESPAPMLVSAGDDGMFKLWTLTTRTHHGKPVERWTCESVGHYRQ 1093

Query: 531  HIGPVLSLAISSNGEQCFSGGIDATIQWWNMPSPNVDPYDTYESNVLAGTLVAHTDAVWG 590
                  ++A  S+     +   D  +  WN            ++NVL  TL   +D +  
Sbjct: 1092 KAA---TMARFSHDGTSLAVVFDTALTLWNP-----------DTNVLMETLSFGSDPILA 955

Query: 591  LAYSGIK 597
            + + G K
Sbjct: 954  VEFGGEK 934
>07665
          Length = 435

 Score = 36.2 bits (82), Expect = 0.051,   Method: Composition-based stats.
 Identities = 33/91 (36%), Positives = 47/91 (51%), Gaps = 2/91 (2%)
 Frame = -2

Query: 473 YTLRSHFDGVRALAFHPVEPVLVTASEDHTLKLWNL--QKTVPAKKSASLDVEPIYTFRA 530
           YTL  H D + AL F P    L  A    ++K+W+L  +KTV   +     V P  T +A
Sbjct: 365 YTLE-HNDIINALCFSPNRYWLCVAY-GPSIKIWDLACKKTVEELRPEV--VSP--TSKA 204

Query: 531 HIGPVLSLAISSNGEQCFSGGIDATIQWWNM 561
                LSLA S++G+  F+G  D TI+ W +
Sbjct: 203 EQPQCLSLAWSTDGQTLFAGYSDNTIRVWQV 111
>19863
          Length = 502

 Score = 36.2 bits (82), Expect = 0.057,   Method: Composition-based stats.
 Identities = 26/81 (32%), Positives = 39/81 (48%), Gaps = 2/81 (2%)
 Frame = +1

Query: 543 NGEQCFSGGIDATIQWWNMPSPNVDPYDTYESNVLAGTLVAHTDAVWGLAYSGIKNQLLS 602
           +G Q  SG  D +I  W++           E+ V    L  H   V  + +S  +  LLS
Sbjct: 4   DGLQLVSGSSDMSIVVWDV-----------ENGVQKLRLQGHAGWVNDVHFSQDQCWLLS 150

Query: 603 CSADGTIRLWNPQE--KLPCV 621
           CS D T+R+WN +E  ++P V
Sbjct: 151 CSNDNTVRIWNIEESDQIPIV 213
>31384
          Length = 474

 Score = 36.2 bits (82), Expect = 0.059,   Method: Compositional matrix adjust.
 Identities = 24/90 (26%), Positives = 40/90 (44%), Gaps = 6/90 (6%)
 Frame = -1

Query: 480 DGVRALAFHP---VEPVLVTASEDHTLKLWNLQK---TVPAKKSASLDVEPIYTFRAHIG 533
           D V  L F P       L++ S D+ +  W +Q+   T+P  +            + H G
Sbjct: 273 DSVSCLKFSPGALPSTFLISGSWDNKVSCWEVQQSGQTIPKAQ------------QTHTG 130

Query: 534 PVLSLAISSNGEQCFSGGIDATIQWWNMPS 563
           PVL +  S +G + F+   D T + W++ S
Sbjct: 129 PVLDVDWSDDGTKVFTASCDKTAKVWDLNS 40
>03387
          Length = 1891

 Score = 35.8 bits (81), Expect = 0.064,   Method: Compositional matrix adjust.
 Identities = 41/146 (28%), Positives = 70/146 (47%), Gaps = 3/146 (2%)
 Frame = +1

Query: 471 PKYTLRSHFDGVRALAFHP-VEPVLVTASEDHTLKLWNLQKTVPAKKSASLDVEPIYTFR 529
           P+  L+ H      L+++P +   L++AS+DHT+ LW++  T   ++S  +D   I+T  
Sbjct: 337 PELRLKGHQKEGYGLSWNPNLNGHLLSASDDHTICLWDINST--QRESRVVDAHTIFT-- 504

Query: 530 AHIGPVLSLAISSNGEQCF-SGGIDATIQWWNMPSPNVDPYDTYESNVLAGTLVAHTDAV 588
            H   V  +A     E  F S   D  +  W+  S       +  S+V+     AHT  V
Sbjct: 505 GHTSVVEDVAWHLLHESLFGSVADDQKLMIWDTRSNTT----SKPSHVVD----AHTAEV 660

Query: 589 WGLAYSGIKNQLLSC-SADGTIRLWN 613
             L+++     +L+  SAD T+ LW+
Sbjct: 661 NCLSFNPYSEFILATGSADKTVALWD 738
>27806
          Length = 419

 Score = 35.8 bits (81), Expect = 0.065,   Method: Compositional matrix adjust.
 Identities = 17/44 (38%), Positives = 25/44 (56%)
 Frame = -1

Query: 474 TLRSHFDGVRALAFHPVEPVLVTASEDHTLKLWNLQKTVPAKKS 517
           T   H   V A+ FHP + +++TAS DHT  +W  Q + P+  S
Sbjct: 314 TYGGHQGSVNAVRFHPGQDLVLTASGDHTAHVWRAQFSQPSLMS 183
>13890
          Length = 630

 Score = 35.4 bits (80), Expect = 0.088,   Method: Compositional matrix adjust.
 Identities = 44/222 (19%), Positives = 84/222 (37%), Gaps = 10/222 (4%)
 Frame = +1

Query: 487 FHPVEPVLVTASEDHTLKLWNLQK-TVPAKKSASLDVEPIYTFRAHIGPVLSLAISSNGE 545
           FHPV P LV       +++W+++   VP +         + T +  +G V  +  S +G+
Sbjct: 4   FHPVTPHLVATGTTDCIQVWDVRHPEVPVR---------VLTHKEQLGQVQDVMFSHDGQ 156

Query: 546 QCFSGG-------IDATIQWWNMPSPNVDPYDTYESNVLAGTLVAHTDAVWGLAYSGIKN 598
           + FS G        D +I  W+  +  +     ++       L+ H            ++
Sbjct: 157 EVFSCGDVVSRESSDRSIMAWDFRTGVILSNQIFQERYTVTRLMLHP----------YQS 306

Query: 599 QLLSCSADGTIRLWNPQE--KLPCVCTYNGDKEHGIPTSVDFIGCDPAHMVTSFNTGSAV 656
           Q L+ +  G I +++ Q   K+     + G K  G       +  D + + +  + G   
Sbjct: 307 QFLAQTQAGYIAVFSTQRPYKMNKNKRFEGHKTAGYNIGAS-LSQDGSIVYSGSSDGKLH 483

Query: 657 IYDLETSQSLVMLSSQVDSGLQSSNHINRVVSHPTLPVTITA 698
            Y   T++ +          L     +  V SHP LP  + A
Sbjct: 484 CYSFNTTKKI--------RTLHCGQVVMDVTSHPLLPSVVAA 585
>12574
          Length = 521

 Score = 35.4 bits (80), Expect = 0.10,   Method: Composition-based stats.
 Identities = 21/79 (26%), Positives = 36/79 (45%)
 Frame = +3

Query: 717 SMVAHLDAVTSLAVDPNGIYLMSGSHDCSIRLWNLDSKTCVQEITAHRKKLDESIYDVAF 776
           ++  H  A++++   PNG +L S S D  I++W        + I  H+  L     DVA+
Sbjct: 171 TLAGHTKALSAVKFSPNGDWLASSSADKLIKIWGAYDGKFEKTIAGHKLGLS----DVAW 338

Query: 777 HPSKAYIASAGADALAKVF 795
                 + SA  D   K++
Sbjct: 339 SSDSKLLCSASDDKTLKIW 395

 Score = 32.0 bits (71), Expect = 0.90,   Method: Composition-based stats.
 Identities = 32/144 (22%), Positives = 56/144 (38%), Gaps = 5/144 (3%)
 Frame = +3

Query: 466 RKTWNPKYTLRSHFDGVRALAFHPVEPVLVTASEDHTLKLW-----NLQKTVPAKKSASL 520
           + T+  K+TL  H   + A+ F P    L ++S D  +K+W       +KT+   K    
Sbjct: 147 KPTYTLKFTLAGHTKALSAVKFSPNGDWLASSSADKLIKIWGAYDGKFEKTIAGHKLGLS 326

Query: 521 DVEPIYTFRAHIGPVLSLAISSNGEQCFSGGIDATIQWWNMPSPNVDPYDTYESNVLAGT 580
           DV                A SS+ +   S   D T++ W            + +     T
Sbjct: 327 DV----------------AWSSDSKLLCSASDDKTLKIWE-----------FSTGKCMKT 425

Query: 581 LVAHTDAVWGLAYSGIKNQLLSCS 604
           L  H++ V+   ++   N ++S S
Sbjct: 426 LKGHSNYVFCCNFNPQSNLIVSGS 497
>01768
          Length = 1424

 Score = 33.9 bits (76), Expect = 0.24,   Method: Compositional matrix adjust.
 Identities = 17/39 (43%), Positives = 25/39 (64%), Gaps = 1/39 (2%)
 Frame = +3

Query: 580 TLVAHTDAVWGLAYSGIK-NQLLSCSADGTIRLWNPQEK 617
           +  AHTD+V  + +S  + N   SCS D T+R+WN Q+K
Sbjct: 822 SYAAHTDSVEDVQWSPNEGNVFASCSVDRTLRIWNTQQK 938
>04524
          Length = 1340

 Score = 33.9 bits (76), Expect = 0.27,   Method: Compositional matrix adjust.
 Identities = 18/60 (30%), Positives = 27/60 (45%), Gaps = 1/60 (1%)
 Frame = -1

Query: 696 ITAHEDRHIKFFDNKTGKMIHS-MVAHLDAVTSLAVDPNGIYLMSGSHDCSIRLWNLDSK 754
           +T   D  I+         IH+  + H   V  L        L+SGS DC++R WN++ K
Sbjct: 980 VTCDRDEKIRVSQFPNAYNIHTYCLGHTQFVNCLVYVEEFRVLISGSGDCTVRAWNMEGK 801
>16199
          Length = 694

 Score = 33.1 bits (74), Expect = 0.39,   Method: Compositional matrix adjust.
 Identities = 16/55 (29%), Positives = 27/55 (49%)
 Frame = +2

Query: 487 FHPVEPVLVTASEDHTLKLWNLQKTVPAKKSASLDVEPIYTFRAHIGPVLSLAIS 541
           FHP   +  T +ED  +K+W+L++              +  F+ H GPV S++ S
Sbjct: 95  FHPDGLIFATGTEDSVIKIWDLKERA-----------NVANFQGHQGPVTSISFS 226

 Score = 30.0 bits (66), Expect = 3.6,   Method: Composition-based stats.
 Identities = 11/41 (26%), Positives = 21/41 (51%)
 Frame = +2

Query: 724 AVTSLAVDPNGIYLMSGSHDCSIRLWNLDSKTCVQEITAHR 764
           A+T     P+G+   +G+ D  I++W+L  +  V     H+
Sbjct: 77  ALTCAQFHPDGLIFATGTEDSVIKIWDLKERANVANFQGHQ 199
>26107
          Length = 1338

 Score = 32.3 bits (72), Expect = 0.68,   Method: Compositional matrix adjust.
 Identities = 29/117 (24%), Positives = 45/117 (38%), Gaps = 11/117 (9%)
 Frame = -3

Query: 521  DVEPIYTFRAHIGPVLSLAISSNGEQCFSGGIDATIQWWNMPSPNVDPYDTYESNVLAGT 580
            D   ++ + AH   V   +  SN  QC +   D T+  W++           E+     T
Sbjct: 1120 DSPTVHRWXAHNNAVFDYSWISNDSQCLTASGDQTVALWDV-----------ETTTKVTT 974

Query: 581  LVAHTDAVWGLAYS-GIKNQLLSCSADGTIRLWNP-----QEKLPC-----VCTYNG 626
             + H  +V  +A       Q  S + DG I LW+      +E  PC     VC  +G
Sbjct: 973  FIGHKCSVRSVASCPSSPAQCASGARDGHIMLWDSRVNKKREHQPCSQVHQVCPQSG 803

 Score = 32.0 bits (71), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 22/68 (32%), Positives = 31/68 (45%), Gaps = 1/68 (1%)
 Frame = -3

Query: 494  LVTASEDHTLKLWNLQKTVPAKKSASLDVEPIYTFRAHIGPVLSLA-ISSNGEQCFSGGI 552
             +TAS D T+ LW+++ T             + TF  H   V S+A   S+  QC SG  
Sbjct: 1042 CLTASGDQTVALWDVETTT-----------KVTTFIGHKCSVRSVASCPSSPAQCASGAR 896

Query: 553  DATIQWWN 560
            D  I  W+
Sbjct: 895  DGHIMLWD 872
>02960
          Length = 1577

 Score = 32.0 bits (71), Expect = 0.95,   Method: Compositional matrix adjust.
 Identities = 42/188 (22%), Positives = 73/188 (38%), Gaps = 21/188 (11%)
 Frame = +2

Query: 472 KYTLRSHFDGVRALAFHPVEPVLVTASEDHTLKLWNLQKTVPAKKSASLDVE-------- 523
           + + R H   V  +A  P    + T S D  LKLW+    V   +S   D E        
Sbjct: 734 RLSCRGHAASVDCVAVSPDSQQMCTGSWDKMLKLWSTDCNVDGDQSE--DTERPSKKKKS 907

Query: 524 ---------PIYTFRAHIGPVLSLAISSNGEQCFSGGIDATIQWWNMPSPNVDPYDTYES 574
                    P+ T   H    +S     +  +  +   D +++ W++ +           
Sbjct: 908 AKSTTQTRVPVLTLSGH-AEAVSAVRWLDPHRVVTSSWDHSLRLWDLHTAQ--------- 1057

Query: 575 NVLAGTLVAHTDAVWGLAYSGIKNQLLSCSADGTIRLWNPQ----EKLPCVCTYNGDKEH 630
                +L+  + AV  +AYS + + L++ SAD  +RL +P+    E + C  T +     
Sbjct: 1058---QTSLIQGSKAVLDVAYSPLSHMLITGSADRHVRLVDPRCSEGETVKCAFTSHT---- 1216

Query: 631 GIPTSVDF 638
           G  T VD+
Sbjct: 1217GWVTGVDW 1240

 Score = 32.0 bits (71), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 53/227 (23%), Positives = 92/227 (40%), Gaps = 38/227 (16%)
 Frame = +2

Query: 601 LSCSADGTIRLWNPQEKLPCVCTYNGDKEHGIPT-SVDFIGCDPAHMVTSFNTGS----A 655
           LS S D T+RLW+   K   + T  G   H  P   V +I  D +  V++F TGS    A
Sbjct: 527 LSGSYDNTVRLWS--TKGEAIMTIPG---HTSPVKCVAWIKHDESSGVSTFVTGSHDQTA 691

Query: 656 VIYDLETSQSLVMLSSQVDSGLQSSNH---INRVVSHPTLPVTITAHEDRHIKFFD---- 708
           +++  +        +++VD  L    H   ++ V   P      T   D+ +K +     
Sbjct: 692 LVWQWQRE------TNEVDCRLSCRGHAASVDCVAVSPDSQQMCTGSWDKMLKLWSTDCN 853

Query: 709 ----------------------NKTGKMIHSMVAHLDAVTSLA-VDPNGIYLMSGSHDCS 745
                                  +T   + ++  H +AV+++  +DP+ +   S  H  S
Sbjct: 854 VDGDQSEDTERPSKKKKSAKSTTQTRVPVLTLSGHAEAVSAVRWLDPHRVVTSSWDH--S 1027

Query: 746 IRLWNLDSKTCVQEITAHRKKL---DESIYDVAFHPSKAYIASAGAD 789
           +RLW+L         TA +  L    +++ DVA+ P    + +  AD
Sbjct: 1028LRLWDLH--------TAQQTSLIQGSKAVLDVAYSPLSHMLITGSAD 1144
>34005
          Length = 456

 Score = 32.0 bits (71), Expect = 1.0,   Method: Composition-based stats.
 Identities = 18/77 (23%), Positives = 37/77 (48%), Gaps = 6/77 (7%)
 Frame = +1

Query: 690 PTLPVTITAHEDRHIKFFDNKTGKMI---HSMVAHLDAVTSLAVDPNGIYLMS---GSHD 743
           P      +   D  +  +D+  G  +   H++ +H  AV ++A  P    +++   G++D
Sbjct: 142 PDATFLASGSNDNSVNIWDSTLGMDVPPLHTLTSHQAAVKAVAWCPWQTRMLATGGGTND 321

Query: 744 CSIRLWNLDSKTCVQEI 760
             IR WN ++  CV+ +
Sbjct: 322 RHIRFWNTNTGACVKAV 372
>12841
          Length = 1364

 Score = 31.6 bits (70), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 17/50 (34%), Positives = 27/50 (54%), Gaps = 1/50 (2%)
 Frame = +1

Query: 580  TLVAHTDAVWGLAYS-GIKNQLLSCSADGTIRLWNPQEKLPCVCTYNGDK 628
            T   HT  V+ + +S  + +  LSCSAD +IRLW+     P +  ++  K
Sbjct: 1033 TYSGHTAPVYHIRWSPFVSDIFLSCSADWSIRLWHQDRTTPILTFHSSTK 1182
>10162
          Length = 1629

 Score = 31.6 bits (70), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 56/290 (19%), Positives = 108/290 (37%), Gaps = 26/290 (8%)
 Frame = +3

Query: 485 LAFHPVEPVLVTASEDHTLKLWNLQKTVPAKKSASLDVEPIYTFRAHIGPVLSLAISSNG 544
           L +H    VL+  ++   + LW     VP++     D   +   ++H  P L   I  NG
Sbjct: 45  LQWHGGAHVLLAGTQGGEVWLWQ----VPSQ-----DYSKMKMLQSHGQPSLCGKILPNG 197

Query: 545 EQCFSGGIDATIQWWNMPSPNVDPYDTYESNVL-------------------AGTLVAHT 585
           +    G  D  ++ W++ +       T++ +V+                          T
Sbjct: 198 KYVCVGYSDGVVKLWDLKTGTA--VHTWQHSVMPEEEMPERNSSDEEDGEEVEVEREEDT 371

Query: 586 DAVWGLAYSGIKNQLLSCSADGTIRLWNPQ-----EKLPCVCTYNGDKEHGIPTSVDFIG 640
            A+  +  S     ++S  AD T +++N           C  + +   +     SV F  
Sbjct: 372 VAILCVDCSADNALIMSGCADATAKVFNVSSGKLXSAFNCAASQDSQDKDNSVESVAFCP 551

Query: 641 CDPAHMVTSFNTGSAVIYDLETSQSLVMLSSQVDSGLQSSNHINRVVSHPTLPVTITAHE 700
             P +  T+ N+GS  ++DL TS +            Q    + ++    +  +  TA  
Sbjct: 552 VSP-YAATATNSGSVQVWDLPTSVA--------RHSFQHPEGVCKLQWSSSTALLYTACL 704

Query: 701 DRHIKFFDNKTGKMIHSMVAHL--DAVTSLAVDPNGIYLMSGSHDCSIRL 748
           D  ++ +D ++G     +  H     +    V  +G  L+SGS D + R+
Sbjct: 705 DGVMRVWDARSGASKAVLTGHARNSCILDFDVTRDGTCLVSGSEDGTARV 854
>04358
          Length = 2430

 Score = 31.6 bits (70), Expect = 1.4,   Method: Compositional matrix adjust.
 Identities = 15/40 (37%), Positives = 26/40 (65%), Gaps = 1/40 (2%)
 Frame = +1

Query: 474  TLRSHFDGVRALAFHPVEPVLV-TASEDHTLKLWNLQKTV 512
            TL  H D + ++ F   +P L+ TAS DHT+++W+ + +V
Sbjct: 1405 TLTGHDDVISSIRFLHTDPGLIMTASHDHTVRIWDPRASV 1524
>31474
          Length = 403

 Score = 31.2 bits (69), Expect = 1.5,   Method: Composition-based stats.
 Identities = 32/113 (28%), Positives = 43/113 (38%), Gaps = 2/113 (1%)
 Frame = -3

Query: 516 KSASLDVEPIYTFRAHIGPVLSLAISSNGEQCFSGGIDATIQWWNMPSPNVDPYDTYESN 575
           K A   +E +    AH      +A +  G    S G D  I+ W     N          
Sbjct: 353 KMAMATLEEVCCLSAHDEHAWCVAWNPTGTLLASCGSDKIIKIWGKEGDNW--------- 201

Query: 576 VLAGTLV-AHTDAVWGLAYSGIKNQLLSCSADGTIRLWNPQ-EKLPCVCTYNG 626
           V   TL  AHT  V  L +S   N L S S D T  +W+ +  +  C+ T  G
Sbjct: 200 VCKSTLTDAHTRTVRSLGWSPCGNYLSSASFDATTAVWSRKGGEFECIATLEG 42

 Score = 29.3 bits (64), Expect = 5.9,   Method: Composition-based stats.
 Identities = 22/81 (27%), Positives = 38/81 (46%), Gaps = 3/81 (3%)
 Frame = -3

Query: 718 MVAHLDAVTSLAVDPNGIYLMSGSHDCSIRLWNL--DSKTCVQEIT-AHRKKLDESIYDV 774
           + AH +    +A +P G  L S   D  I++W    D+  C   +T AH +    ++  +
Sbjct: 317 LSAHDEHAWCVAWNPTGTLLASCGSDKIIKIWGKEGDNWVCKSTLTDAHTR----TVRSL 150

Query: 775 AFHPSKAYIASAGADALAKVF 795
            + P   Y++SA  DA   V+
Sbjct: 149 GWSPCGNYLSSASFDATTAVW 87
>38362
          Length = 1255

 Score = 31.2 bits (69), Expect = 1.7,   Method: Compositional matrix adjust.
 Identities = 16/55 (29%), Positives = 25/55 (45%), Gaps = 2/55 (3%)
 Frame = -1

Query: 579 GTLVAHTDAVWGLAYSGIKNQLLSCSADGTIRLW--NPQEKLPCVCTYNGDKEHG 631
           G   +H   VW ++++     L+S  ADG +R+W  N      C+    GD   G
Sbjct: 634 GLFDSHDSQVWRVSWNVTGTILVSSGADGCVRIWKANYLGSWACISVLKGDGTPG 470
>14555
          Length = 627

 Score = 30.8 bits (68), Expect = 2.0,   Method: Composition-based stats.
 Identities = 14/49 (28%), Positives = 25/49 (51%)
 Frame = -3

Query: 701 DRHIKFFDNKTGKMIHSMVAHLDAVTSLAVDPNGIYLMSGSHDCSIRLW 749
           D  +  +D   G     +  H + V+ L + P+G  L +GS D ++R+W
Sbjct: 403 DYTVNVWDALKGMRSTILYGHDNRVSCLRISPDGTSLCTGSWDYTLRIW 257
>18320
          Length = 450

 Score = 30.8 bits (68), Expect = 2.2,   Method: Compositional matrix adjust.
 Identities = 19/69 (27%), Positives = 34/69 (49%)
 Frame = -2

Query: 493 VLVTASEDHTLKLWNLQKTVPAKKSASLDVEPIYTFRAHIGPVLSLAISSNGEQCFSGGI 552
           +L   S D  L L +L K  PA+  +  D++     +AH G +  +A  S  +  ++G  
Sbjct: 242 LLAAGSRDRYLTLLDLTKYDPARPKSKKDMQLHCIDKAHSGWIWCMA--SLNQHLYTGSW 69

Query: 553 DATIQWWNM 561
           D  I+ W++
Sbjct: 68  DTKIKVWDL 42
>21960
          Length = 756

 Score = 30.4 bits (67), Expect = 2.5,   Method: Compositional matrix adjust.
 Identities = 17/72 (23%), Positives = 38/72 (52%)
 Frame = +1

Query: 636 VDFIGCDPAHMVTSFNTGSAVIYDLETSQSLVMLSSQVDSGLQSSNHINRVVSHPTLPVT 695
           V+F G    H+++  + G+   +D + ++++       D+G+     +N +  HPT+PV 
Sbjct: 379 VNFFGPHSEHIISGSDDGNIFYWD-KNTEAVTNFMKGDDAGV-----VNCLEQHPTMPVL 540

Query: 696 ITAHEDRHIKFF 707
            T+  D ++K +
Sbjct: 541 ATSGLDHNVKIW 576

 Score = 30.4 bits (67), Expect = 2.9,   Method: Compositional matrix adjust.
 Identities = 12/25 (48%), Positives = 15/25 (60%)
 Frame = +1

Query: 482 VRALAFHPVEPVLVTASEDHTLKLW 506
           V  L  HP  PVL T+  DH +K+W
Sbjct: 502 VNCLEQHPTMPVLATSGLDHNVKIW 576
>05393
          Length = 904

 Score = 30.4 bits (67), Expect = 3.3,   Method: Compositional matrix adjust.
 Identities = 16/61 (26%), Positives = 30/61 (49%), Gaps = 1/61 (1%)
 Frame = +1

Query: 454 YSYDLPANKDAFRKTWNPKYTLRSHFDGVRALAFHPVEP-VLVTASEDHTLKLWNLQKTV 512
           Y +D+   K        P +++ +H   V  +      P +++T SED T+K+W++Q   
Sbjct: 169 YCFDIRHEK--------PVFSVGAHSSCVTGVCLSSQIPGLMITTSEDKTMKVWDIQDDK 324

Query: 513 P 513
           P
Sbjct: 325 P 327
>01805
          Length = 2124

 Score = 30.0 bits (66), Expect = 3.4,   Method: Compositional matrix adjust.
 Identities = 13/44 (29%), Positives = 25/44 (56%), Gaps = 1/44 (2%)
 Frame = -1

Query: 471 PKYTLRSHFDGVRALAFHPVEP-VLVTASEDHTLKLWNLQKTVP 513
           P +++ +H   V  +      P +++T SED T+K+W++Q   P
Sbjct: 213 PVFSVGAHSSCVTGVCLSSQIPGLMITTSEDKTMKVWDIQDDKP 82
>34511
          Length = 1037

 Score = 30.0 bits (66), Expect = 3.5,   Method: Composition-based stats.
 Identities = 12/33 (36%), Positives = 20/33 (60%)
 Frame = +3

Query: 718 MVAHLDAVTSLAVDPNGIYLMSGSHDCSIRLWN 750
           +  H + V+ L V  NG+ + +GS D  +R+WN
Sbjct: 60  LAGHDNRVSCLGVTENGMSVATGSWDSFLRVWN 158
>08679
          Length = 2028

 Score = 30.0 bits (66), Expect = 3.9,   Method: Compositional matrix adjust.
 Identities = 26/85 (30%), Positives = 40/85 (47%), Gaps = 3/85 (3%)
 Frame = -3

Query: 482  VRALAFHPVEP-VLVTASEDHTLKLWNLQKTVPAKKSASLDVEPIYTFRAHIGPVLSLAI 540
            +R+++ HP  P   VTA  D    +W+L+K      SAS   EP+++     G  +S A 
Sbjct: 1534 LRSVSVHPTNPHFFVTAGSDMKXSVWDLRKL-----SASKGNEPLHSMMH--GKTVSSAY 1376

Query: 541  SS--NGEQCFSGGIDATIQWWNMPS 563
             S   G +  S   D T+  +N  S
Sbjct: 1375 FSPLTGARILSCSADDTLNVFNCSS 1301
>30295
          Length = 593

 Score = 29.6 bits (65), Expect = 4.5,   Method: Composition-based stats.
 Identities = 33/143 (23%), Positives = 59/143 (41%), Gaps = 1/143 (0%)
 Frame = +2

Query: 472 KYTLRSHFDGVRALAFHPVEPVLVTASEDHTLKLWNLQKTVPAKKSASLDVEPIYTFRAH 531
           + TLR H   + A+ +      LV+AS+D  L +W+   T             ++     
Sbjct: 224 RRTLRXHLAKIYAMHWATDSRNLVSASQDGKLIVWDGYTT-----------NKVHAIPLR 370

Query: 532 IGPVLSLAISSNGEQCFSGGIDATIQWWNMPSPNVDPYDTYESNV-LAGTLVAHTDAVWG 590
              V++ A + +G     GG+D     +++         T E NV ++  L  HT  +  
Sbjct: 371 SSWVMTCAYAPSGGYVACGGLDNICSIYSL--------KTREGNVRVSRELPGHTGYLSC 526

Query: 591 LAYSGIKNQLLSCSADGTIRLWN 613
             +    NQ+++ S D T  LW+
Sbjct: 527 CRFID-DNQIVTSSGDMTCALWD 592
>31864
          Length = 545

 Score = 29.6 bits (65), Expect = 4.8,   Method: Compositional matrix adjust.
 Identities = 35/132 (26%), Positives = 53/132 (40%), Gaps = 10/132 (7%)
 Frame = +2

Query: 673 VDSGLQSSNHINRVVSHPTLPVTITAHEDRHIKFFDNKTGKMIHSMVAHLDAVTSLAVDP 732
           VDSG+  +  IN +       + +TA +D   K FD+++  M          V S A+ P
Sbjct: 29  VDSGVDHTGGINDMQLSKDGTMFVTASKDTTAKLFDSES-LMCLKTYKTERPVNSAAISP 205

Query: 733 NGIY-LMSGSHDC------SIRLWNLDSK---TCVQEITAHRKKLDESIYDVAFHPSKAY 782
              + ++ G  D       S +    DS+      +E  A  K     I  +AFHP    
Sbjct: 206 ILDHVVLGGGQDAMEVTTTSTKAGKFDSRFFHLIYEEEFARLKGHFGPINSLAFHPDGKS 385

Query: 783 IASAGADALAKV 794
            AS G D   +V
Sbjct: 386 YASGGEDGFVRV 421

 Score = 29.3 bits (64), Expect = 7.3,   Method: Compositional matrix adjust.
 Identities = 30/122 (24%), Positives = 54/122 (44%), Gaps = 10/122 (8%)
 Frame = +2

Query: 642 DPAHMVTSFNTGSAVIYDLETSQSLVMLSSQVDSGLQSSNHINRVVSHPTL-----PVTI 696
           D    VT+    +A ++D   S+SL+ L +       +S  I+ ++ H  L      + +
Sbjct: 83  DGTMFVTASKDTTAKLFD---SESLMCLKTYKTERPVNSAAISPILDHVVLGGGQDAMEV 253

Query: 697 TAHEDRHIKFFDNKTGKMIHS-----MVAHLDAVTSLAVDPNGIYLMSGSHDCSIRLWNL 751
           T    +  KF D++   +I+      +  H   + SLA  P+G    SG  D  +R+ + 
Sbjct: 254 TTTSTKAGKF-DSRFFHLIYEEEFARLKGHFGPINSLAFHPDGKSYASGGEDGFVRVKSF 430

Query: 752 DS 753
           DS
Sbjct: 431 DS 436
>30297
          Length = 822

 Score = 28.9 bits (63), Expect = 8.9,   Method: Compositional matrix adjust.
 Identities = 11/39 (28%), Positives = 23/39 (58%)
 Frame = -1

Query: 714 MIHSMVAHLDAVTSLAVDPNGIYLMSGSHDCSIRLWNLD 752
           +I S   H+++V+ L +      L++ + DC++R+W  D
Sbjct: 252 VIQSWRGHVESVSCLDLVEQNKVLLTSAADCTVRMWTTD 136
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6753060|ref|NP_033803.1| annexin A5 [Mus musculus]
         (319 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

32521                                                                 244   3e-65
36934                                                                 142   1e-34
06659                                                                 135   2e-32
22178                                                                 102   2e-30
13827                                                                  67   3e-12
12136                                                                  64   7e-11
17882                                                                  57   1e-08
29756                                                                  54   7e-08
>32521
          Length = 1241

 Score =  244 bits (624), Expect = 3e-65,   Method: Compositional matrix adjust.
 Identities = 123/268 (45%), Positives = 176/268 (65%)
 Frame = +2

Query: 47  QRQEIAQEFKTLFGRDLVDDLKSELTGKFEKLIVAMMKPSRLYDAYELKHALKGAGTDEK 106
           QR+EI   +KT+FG+DL  +L  EL+G F+ L V M+     +DA ++  A+KG GTDE+
Sbjct: 5   QRREINLTYKTMFGKDLGKELSGELSGNFKTLCVEMLLGPAEFDAKQINKAVKGLGTDER 184

Query: 107 VLTEIIASRTPEELSAIKQVYEEEYGSNLEDDVVGDTSGYYQRMLVVLLQANRDPDTAID 166
            L EII +RT  +L+A+K+ Y+  Y  ++E D+ GDTSG ++R+L+  LQANR      D
Sbjct: 185 ALIEIICTRTNAQLTAMKEAYKTMYQKDVETDIEGDTSGPFKRLLIGCLQANRPEGQEFD 364

Query: 167 DAQVELDAQALFQAGELKWGTDEEKFITIFGTRSVSHLRRVFDKYMTISGFQIEETIDRE 226
             + + DAQAL +AGE KWGTDE +F  +  +RS   LR  F +Y  ++   IE++I  E
Sbjct: 365 RNKAKQDAQALLEAGEKKWGTDESRFNVVIVSRSFPQLRATFQEYAKLANKDIEDSISSE 544

Query: 227 TSGNLEQLLLAVVKSIRSIPAYLAETLYYAMKGAGTDDHTLIRVVVSRSEIDLFNIRKEF 286
            SG+ +  +L VV+ IRS   + A  L+ AMKG GTDD TL+RVV SR E+D+  I++EF
Sbjct: 545 MSGDXKNGMLTVVRVIRSKATHFATELHRAMKGLGTDDDTLVRVVASRCEVDMVQIKEEF 724

Query: 287 RKNFATSLYSMIKGDTSGDYKKALLLLC 314
           ++NF  +LYS I  DTSGDY+   L+LC
Sbjct: 725 QRNFKQTLYSFIVDDTSGDYR---LMLC 799

 Score = 74.7 bits (182), Expect = 4e-14,   Method: Compositional matrix adjust.
 Identities = 57/234 (24%), Positives = 118/234 (50%), Gaps = 12/234 (5%)
 Frame = +2

Query: 18  DAEVLRKAMKGLGTDEDSILNLLTSRSNAQRQEIAQEFKTLFGRDLVDDLKSELTGKFEK 77
           DA+ + KA+KGLGTDE +++ ++ +R+NAQ   + + +KT++ +D+  D++ + +G F++
Sbjct: 134 DAKQINKAVKGLGTDERALIEIICTRTNAQLTAMKEAYKTMYQKDVETDIEGDTSGPFKR 313

Query: 78  LIVAMMKPSRL-----------YDAYELKHA-LKGAGTDEKVLTEIIASRTPEELSAIKQ 125
           L++  ++ +R             DA  L  A  K  GTDE     +I SR+  +L A  Q
Sbjct: 314 LLIGCLQANRPEGQEFDRNKAKQDAQALLEAGEKKWGTDESRFNVVIVSRSFPQLRATFQ 493

Query: 126 VYEEEYGSNLEDDVVGDTSGYYQRMLVVLLQANRDPDTAIDDAQVELDAQALFQAGELKW 185
            Y +    ++ED +  + SG  +  ++ +++  R   T          A  L +A +   
Sbjct: 494 EYAKLANKDIEDSISSEMSGDXKNGMLTVVRVIRSKATHF--------ATELHRAMK-GL 646

Query: 186 GTDEEKFITIFGTRSVSHLRRVFDKYMTISGFQIEETIDRETSGNLEQLLLAVV 239
           GTD++  + +  +R    + ++ +++       +   I  +TSG+   +L  ++
Sbjct: 647 GTDDDTLVRVVASRCEVDMVQIKEEFQRNFKQTLYSFIVDDTSGDYRLMLCNLI 808
>36934
          Length = 667

 Score =  142 bits (359), Expect = 1e-34,   Method: Compositional matrix adjust.
 Identities = 69/161 (42%), Positives = 112/161 (69%), Gaps = 1/161 (0%)
 Frame = +3

Query: 18  DAEVLRKAMKGLG-TDEDSILNLLTSRSNAQRQEIAQEFKTLFGRDLVDDLKSELTGKFE 76
           DAE L KAM G+G T ED++L ++  RSN+QRQ + +++K ++ RDL + L+SELTG FE
Sbjct: 27  DAERLHKAMSGMGVTHEDTVLEIIIKRSNSQRQTLKKKYKEMYKRDLAEHLQSELTGDFE 206

Query: 77  KLIVAMMKPSRLYDAYELKHALKGAGTDEKVLTEIIASRTPEELSAIKQVYEEEYGSNLE 136
           +LI+ ++ P   YDA+ L  A+ G GT+E VL  I+ +  P+ELS++K+VY++ YG +L+
Sbjct: 207 ELILGLLMPPVEYDAFCLNKAVDGLGTNEDVLIGILCTANPKELSSVKEVYKKTYGEDLD 386

Query: 137 DDVVGDTSGYYQRMLVVLLQANRDPDTAIDDAQVELDAQAL 177
             + GDTSG ++ +L+ L +  RD   ++++ + + DAQ L
Sbjct: 387 SAIKGDTSGGFEDLLLALSRGERDQSKSVNEKEAKQDAQKL 509

 Score = 61.6 bits (148), Expect = 4e-10,   Method: Compositional matrix adjust.
 Identities = 45/149 (30%), Positives = 78/149 (52%), Gaps = 2/149 (1%)
 Frame = +3

Query: 173 DAQALFQAGELKWGTDEEKFITIFGTRSVSHLRRVFDKYMTISGFQIEETIDRETSGNLE 232
           DA+ L +A      T E+  + I   RS S  + +  KY  +    + E +  E +G+ E
Sbjct: 27  DAERLHKAMSGMGVTHEDTVLEIIIKRSNSQRQTLKKKYKEMYKRDLAEHLQSELTGDFE 206

Query: 233 QLLLAVVKSIRSIPA--YLAETLYYAMKGAGTDDHTLIRVVVSRSEIDLFNIRKEFRKNF 290
           +L+L ++     +P   Y A  L  A+ G GT++  LI ++ + +  +L ++++ ++K +
Sbjct: 207 ELILGLL-----MPPVEYDAFCLNKAVDGLGTNEDVLIGILCTANPKELSSVKEVYKKTY 371

Query: 291 ATSLYSMIKGDTSGDYKKALLLLCGGEDD 319
              L S IKGDTSG ++  LL L  GE D
Sbjct: 372 GEDLDSAIKGDTSGGFEDLLLALSRGERD 458
>06659
          Length = 776

 Score =  135 bits (341), Expect = 2e-32,   Method: Compositional matrix adjust.
 Identities = 89/224 (39%), Positives = 133/224 (59%), Gaps = 4/224 (1%)
 Frame = -3

Query: 94  LKHALKGAGTDEKVLTEIIASRTPEELSAIKQVYEEEYGSNLEDDVVGDTSGYYQRMLVV 153
           L  A+ GAGTDEK L +I+ +R  +E+  IK+ Y+EE+ S LE+D+  DT GY++R+++ 
Sbjct: 774 LHDAISGAGTDEKCLIDIMCTRDNDEMKEIKEKYKEEFESELEEDLQADTGGYFRRLMIS 595

Query: 154 LLQANRDPDT---AIDDAQVELDAQALFQAGELKWGTDEEKFITIFGTRSVSHLRRVFDK 210
           L    RD D    A +D  VE DAQ   +AGE  WGT+E     I    S + L +  +K
Sbjct: 594 LCVGGRDYDNWWXANEDKAVE-DAQKFLEAGENAWGTEEADMNAILCRTSPAQLCKTIEK 418

Query: 211 YMTIS-GFQIEETIDRETSGNLEQLLLAVVKSIRSIPAYLAETLYYAMKGAGTDDHTLIR 269
           Y  ++ G  +EE+I  E S +L    LA+V+S RS+P Y A  L     G GT D+ LIR
Sbjct: 417 YEELTEGKTMEESIRSECSDDLXDGYLAIVESARSMPRYFARRLNDCFSGLGTSDNDLIR 238

Query: 270 VVVSRSEIDLFNIRKEFRKNFATSLYSMIKGDTSGDYKKALLLL 313
           ++VSRSE+DL  I++ + + +   L   ++ +  GDYK+ LL +
Sbjct: 237 IIVSRSEVDLEAIKQAYEEMYEKPLTEAVESECGGDYKRLLLAI 106

 Score = 57.8 bits (138), Expect = 6e-09,   Method: Compositional matrix adjust.
 Identities = 41/139 (29%), Positives = 69/139 (49%), Gaps = 4/139 (2%)
 Frame = -3

Query: 22  LRKAMKGLGTDEDSILNLLTSRSNAQRQEIAQEFKTLF-GRDLVDDLKSELTGKFEKLIV 80
           L       GT+E  +  +L   S AQ  +  ++++ L  G+ + + ++SE +       +
Sbjct: 516 LEAGENAWGTEEADMNAILCRTSPAQLCKTIEKYEELTEGKTMEESIRSECSDDLXDGYL 337

Query: 81  AMMKPSR---LYDAYELKHALKGAGTDEKVLTEIIASRTPEELSAIKQVYEEEYGSNLED 137
           A+++ +R    Y A  L     G GT +  L  II SR+  +L AIKQ YEE Y   L +
Sbjct: 336 AIVESARSMPRYFARRLNDCFSGLGTSDNDLIRIIVSRSEVDLEAIKQAYEEMYEKPLTE 157

Query: 138 DVVGDTSGYYQRMLVVLLQ 156
            V  +  G Y+R+L+ +L 
Sbjct: 156 AVESECGGDYKRLLLAILN 100

 Score = 44.7 bits (104), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 18/67 (26%), Positives = 40/67 (59%)
 Frame = -3

Query: 19  AEVLRKAMKGLGTDEDSILNLLTSRSNAQRQEIAQEFKTLFGRDLVDDLKSELTGKFEKL 78
           A  L     GLGT ++ ++ ++ SRS    + I Q ++ ++ + L + ++SE  G +++L
Sbjct: 297 ARRLNDCFSGLGTSDNDLIRIIVSRSEVDLEAIKQAYEEMYEKPLTEAVESECGGDYKRL 118

Query: 79  IVAMMKP 85
           ++A++ P
Sbjct: 117 LLAILNP 97

 Score = 30.8 bits (68), Expect = 0.80,   Method: Compositional matrix adjust.
 Identities = 21/67 (31%), Positives = 43/67 (64%), Gaps = 1/67 (1%)
 Frame = -3

Query: 253 LYYAMKGAGTDDHTLIRVVVSRSEIDLFNIRKEFRKNFATSLYSMIKGDTSGDYKKALLL 312
           L+ A+ GAGTD+  LI ++ +R   ++  I++++++ F + L   ++ DT G +++ ++ 
Sbjct: 774 LHDAISGAGTDEKCLIDIMCTRDNDEMKEIKEKYKEEFESELEEDLQADTGGYFRRLMIS 595

Query: 313 LC-GGED 318
           LC GG D
Sbjct: 594 LCVGGRD 574
>22178
          Length = 655

 Score =  102 bits (254), Expect(2) = 2e-30,   Method: Compositional matrix adjust.
 Identities = 50/82 (60%), Positives = 62/82 (75%)
 Frame = +1

Query: 234 LLLAVVKSIRSIPAYLAETLYYAMKGAGTDDHTLIRVVVSRSEIDLFNIRKEFRKNFATS 293
           L LA+V+  R+ PAY AE LY +MKGAGT+D  LIR +VSRSE DL  I++EF++ +  +
Sbjct: 214 LFLAIVRVARNTPAYFAERLYKSMKGAGTNDKALIRAIVSRSENDLGFIKQEFQRMYGKT 393

Query: 294 LYSMIKGDTSGDYKKALLLLCG 315
           L S IKGDTSGDYKK LL LCG
Sbjct: 394 LASYIKGDTSGDYKKILLALCG 459

 Score = 47.4 bits (111), Expect(2) = 2e-30,   Method: Compositional matrix adjust.
 Identities = 25/47 (53%), Positives = 27/47 (57%)
 Frame = +2

Query: 186 GTDEEKFITIFGTRSVSHLRRVFDKYMTISGFQIEETIDRETSGNLE 232
           GTDEE F  I   R+   LR  FD Y  ISG  IE+ I  E SGNLE
Sbjct: 68  GTDEETFNRILCLRNYGQLRATFDAYRQISGKDIEDAIKSEMSGNLE 208

 Score = 58.2 bits (139), Expect(2) = 3e-13,   Method: Compositional matrix adjust.
 Identities = 32/85 (37%), Positives = 49/85 (57%)
 Frame = +1

Query: 70  ELTGKFEKLIVAMMKPSRLYDAYELKHALKGAGTDEKVLTEIIASRTPEELSAIKQVYEE 129
           +L G     IV + + +  Y A  L  ++KGAGT++K L   I SR+  +L  IKQ ++ 
Sbjct: 199 QLGGGLFLAIVRVARNTPAYFAERLYKSMKGAGTNDKALIRAIVSRSENDLGFIKQEFQR 378

Query: 130 EYGSNLEDDVVGDTSGYYQRMLVVL 154
            YG  L   + GDTSG Y+++L+ L
Sbjct: 379 MYGKTLASYIKGDTSGDYKKILLAL 453

 Score = 33.5 bits (75), Expect(2) = 3e-13,   Method: Compositional matrix adjust.
 Identities = 17/66 (25%), Positives = 34/66 (51%)
 Frame = +2

Query: 11 PGFDGRADAEVLRKAMKGLGTDEDSILNLLTSRSNAQRQEIAQEFKTLFGRDLVDDLKSE 70
          P    R  +   +   + +GTDE++   +L  R+  Q +     ++ + G+D+ D +KSE
Sbjct: 11 PSPCKRPTSSTRQGERESVGTDEETFNRILCLRNYGQLRATFDAYRQISGKDIEDAIKSE 190

Query: 71 LTGKFE 76
          ++G  E
Sbjct: 191MSGNLE 208

 Score = 48.5 bits (114), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 22/64 (34%), Positives = 42/64 (65%)
 Frame = +1

Query: 19  AEVLRKAMKGLGTDEDSILNLLTSRSNAQRQEIAQEFKTLFGRDLVDDLKSELTGKFEKL 78
           AE L K+MKG GT++ +++  + SRS      I QEF+ ++G+ L   +K + +G ++K+
Sbjct: 262 AERLYKSMKGAGTNDKALIRAIVSRSENDLGFIKQEFQRMYGKTLASYIKGDTSGDYKKI 441

Query: 79  IVAM 82
           ++A+
Sbjct: 442 LLAL 453

 Score = 26.2 bits (56), Expect(2) = 0.17,   Method: Compositional matrix adjust.
 Identities = 14/44 (31%), Positives = 22/44 (50%)
 Frame = +2

Query: 102 GTDEKVLTEIIASRTPEELSAIKQVYEEEYGSNLEDDVVGDTSG 145
           GTDE+    I+  R   +L A    Y +  G ++ED +  + SG
Sbjct: 68  GTDEETFNRILCLRNYGQLRATFDAYRQISGKDIEDAIKSEMSG 199

 Score = 25.4 bits (54), Expect(2) = 0.17,   Method: Compositional matrix adjust.
 Identities = 14/54 (25%), Positives = 30/54 (55%)
 Frame = +1

Query: 186 GTDEEKFITIFGTRSVSHLRRVFDKYMTISGFQIEETIDRETSGNLEQLLLAVV 239
           GT+++  I    +RS + L  +  ++  + G  +   I  +TSG+ +++LLA+ 
Sbjct: 295 GTNDKALIRAIVSRSENDLGFIKQEFQRMYGKTLASYIKGDTSGDYKKILLALC 456
>13827
          Length = 483

 Score = 66.6 bits (161), Expect(2) = 3e-12,   Method: Compositional matrix adjust.
 Identities = 28/59 (47%), Positives = 43/59 (72%)
 Frame = -1

Query: 258 KGAGTDDHTLIRVVVSRSEIDLFNIRKEFRKNFATSLYSMIKGDTSGDYKKALLLLCGG 316
           +G GTDD TLIRVVV+R E+D+  I++EF+  +  +L + ++ D SGDY++ +L L GG
Sbjct: 444 RGMGTDDRTLIRVVVTRCEVDMKQIKQEFQNRYGQALEAFVRDDISGDYRRLMLALVGG 268

 Score = 21.9 bits (45), Expect(2) = 3e-12,   Method: Compositional matrix adjust.
 Identities = 8/15 (53%), Positives = 11/15 (73%)
 Frame = -3

Query: 247 AYLAETLYYAMKGAG 261
            Y A+ LY++MKG G
Sbjct: 478 GYFADRLYHSMKGDG 434

 Score = 46.6 bits (109), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 20/57 (35%), Positives = 35/57 (61%)
 Frame = -1

Query: 99  KGAGTDEKVLTEIIASRTPEELSAIKQVYEEEYGSNLEDDVVGDTSGYYQRMLVVLL 155
           +G GTD++ L  ++ +R   ++  IKQ ++  YG  LE  V  D SG Y+R+++ L+
Sbjct: 444 RGMGTDDRTLIRVVVTRCEVDMKQIKQEFQNRYGQALEAFVRDDISGDYRRLMLALV 274

 Score = 40.0 bits (92), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 14/57 (24%), Positives = 39/57 (68%)
 Frame = -1

Query: 27  KGLGTDEDSILNLLTSRSNAQRQEIAQEFKTLFGRDLVDDLKSELTGKFEKLIVAMM 83
           +G+GTD+ +++ ++ +R     ++I QEF+  +G+ L   ++ +++G + +L++A++
Sbjct: 444 RGMGTDDRTLIRVVVTRCEVDMKQIKQEFQNRYGQALEAFVRDDISGDYRRLMLALV 274
>12136
          Length = 445

 Score = 63.9 bits (154), Expect = 7e-11,   Method: Compositional matrix adjust.
 Identities = 33/104 (31%), Positives = 62/104 (59%), Gaps = 7/104 (6%)
 Frame = +3

Query: 63  LVDDLKSELTGKFEKLIVAMMKPSRLYDAYELKHALKGAGTDEKVLTEIIASRTPEELSA 122
           L++++K EL+G +++L++A+      YDA+ +K A+ G GTDE  L EI+ +RT  ++  
Sbjct: 3   LIEEIKGELSGDYKELVMALFVAPAEYDAWCIKEAIYGPGTDEMALMEILMTRTNAQIKE 182

Query: 123 IKQVY-----EEEYG--SNLEDDVVGDTSGYYQRMLVVLLQANR 159
           ++ +Y     +  +G    +E D+  D SG ++R+L+   Q  R
Sbjct: 183 LRSIYPSVLNDHYHGRTPKIEQDIEDDCSGDFKRLLISASQGGR 314

 Score = 40.0 bits (92), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 21/78 (26%), Positives = 47/78 (60%), Gaps = 7/78 (8%)
 Frame = +3

Query: 18  DAEVLRKAMKGLGTDEDSILNLLTSRSNAQRQEIAQEFKTLF-----GR--DLVDDLKSE 70
           DA  +++A+ G GTDE +++ +L +R+NAQ +E+   + ++      GR   +  D++ +
Sbjct: 84  DAWCIKEAIYGPGTDEMALMEILMTRTNAQIKELRSIYPSVLNDHYHGRTPKIEQDIEDD 263

Query: 71  LTGKFEKLIVAMMKPSRL 88
            +G F++L+++  +  R 
Sbjct: 264 CSGDFKRLLISASQGGRF 317
>17882
          Length = 489

 Score = 56.6 bits (135), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 27/55 (49%), Positives = 38/55 (69%)
 Frame = -1

Query: 261 GTDDHTLIRVVVSRSEIDLFNIRKEFRKNFATSLYSMIKGDTSGDYKKALLLLCG 315
           GT+D  LIR++VSRSEIDL +I+  +   +  +L S +  DTSGDYK+ LL + G
Sbjct: 351 GTNDSRLIRIIVSRSEIDLQDIKDVYLSKYKKTLESAVASDTSGDYKRLLLAIVG 187

 Score = 44.7 bits (104), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 23/54 (42%), Positives = 33/54 (61%)
 Frame = -1

Query: 102 GTDEKVLTEIIASRTPEELSAIKQVYEEEYGSNLEDDVVGDTSGYYQRMLVVLL 155
           GT++  L  II SR+  +L  IK VY  +Y   LE  V  DTSG Y+R+L+ ++
Sbjct: 351 GTNDSRLIRIIVSRSEIDLQDIKDVYLSKYKKTLESAVASDTSGDYKRLLLAIV 190

 Score = 34.7 bits (78), Expect = 0.059,   Method: Compositional matrix adjust.
 Identities = 18/54 (33%), Positives = 33/54 (61%)
 Frame = -1

Query: 186 GTDEEKFITIFGTRSVSHLRRVFDKYMTISGFQIEETIDRETSGNLEQLLLAVV 239
           GT++ + I I  +RS   L+ + D Y++     +E  +  +TSG+ ++LLLA+V
Sbjct: 351 GTNDSRLIRIIVSRSEIDLQDIKDVYLSKYKKTLESAVASDTSGDYKRLLLAIV 190

 Score = 30.0 bits (66), Expect = 1.4,   Method: Compositional matrix adjust.
 Identities = 13/55 (23%), Positives = 34/55 (61%)
 Frame = -1

Query: 29  LGTDEDSILNLLTSRSNAQRQEIAQEFKTLFGRDLVDDLKSELTGKFEKLIVAMM 83
           LGT++  ++ ++ SRS    Q+I   + + + + L   + S+ +G +++L++A++
Sbjct: 354 LGTNDSRLIRIIVSRSEIDLQDIKDVYLSKYKKTLESAVASDTSGDYKRLLLAIV 190
>29756
          Length = 496

 Score = 54.3 bits (129), Expect = 7e-08,   Method: Compositional matrix adjust.
 Identities = 28/75 (37%), Positives = 44/75 (58%), Gaps = 1/75 (1%)
 Frame = +3

Query: 10  FPGFDGRADAEVLRKAMKGLGTDEDSILNLLTSRSNAQRQEIAQEFKTLFGRDLVDDL-K 68
           +P F+   D + LRKAMKG GTDE +I+++L  R++ QRQ +   +K LF +       +
Sbjct: 255 YPRFNAEEDVQKLRKAMKGFGTDEKAIIDILGYRTSDQRQNLKLMYKNLFWKRFGAGF*R 434

Query: 69  SELTGKFEKLIVAMM 83
               G FE  ++A+M
Sbjct: 435 VN*AGAFEDAMLALM 479

 Score = 35.8 bits (81), Expect = 0.026,   Method: Compositional matrix adjust.
 Identities = 15/40 (37%), Positives = 26/40 (65%)
 Frame = +3

Query: 90  DAYELKHALKGAGTDEKVLTEIIASRTPEELSAIKQVYEE 129
           D  +L+ A+KG GTDEK + +I+  RT ++   +K +Y+ 
Sbjct: 279 DVQKLRKAMKGFGTDEKAIIDILGYRTSDQRQNLKLMYKN 398
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|112363072|ref|NP_083987.1| actin related protein 2/3
complex, subunit 2 [Mus musculus]
         (300 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

05348                                                                 244   4e-65
31465                                                                 118   2e-32
07059                                                                  30   1.4  
38284                                                                  30   1.6  
30690                                                                  27   6.8  
22961                                                                  27   7.9  
>05348
          Length = 1459

 Score =  244 bits (622), Expect = 4e-65,   Method: Compositional matrix adjust.
 Identities = 116/144 (80%), Positives = 128/144 (88%), Gaps = 1/144 (0%)
 Frame = -2

Query: 156  SKKDRVTVVFSTVFKDDDDVVIGKVFMQEFKEGRRASHTAPQVLFSHREPPLELKDTDAA 215
            +KKDRVTV+FST+FKDDDD++IGKVFMQEFKEGRR    APQVLFSH+EPP EL+ TDA 
Sbjct: 1458 AKKDRVTVIFSTLFKDDDDIIIGKVFMQEFKEGRRKYQQAPQVLFSHKEPPQELQGTDAR 1279

Query: 216  VGDNIGYITFVLFPRHTNATARDNTINLIHTFRDYLHYHIKCSKAYIHT-RMRAKTSDFL 274
             GDNIGYITFVLFPRHT+A ARDNTINLIHT RDYLHYHIKCSKAY  T RMRAKTSDFL
Sbjct: 1278 TGDNIGYITFVLFPRHTSAAARDNTINLIHTLRDYLHYHIKCSKAYRFTERMRAKTSDFL 1099

Query: 275  KVLNRARPDAEKKEMKTITGKTFS 298
            KVLNRARP+ + KE KTITG+TF+
Sbjct: 1098 KVLNRARPEVKDKEKKTITGRTFN 1027
>31465
          Length = 417

 Score =  118 bits (295), Expect(2) = 2e-32,   Method: Compositional matrix adjust.
 Identities = 54/85 (63%), Positives = 69/85 (81%)
 Frame = +2

Query: 1   MILLEVNNRIIEETLALKFENAAAGNKPEAVEVTFADFDGVLYHISNPNGDKTKVMVSIS 60
           MILLE  N I++ETL  K  N   G KP+ V++T ADFDGVLYHISNP+G+K++++VS+S
Sbjct: 83  MILLEYKNLIVQETLKEKIRNVLDGGKPDNVDITVADFDGVLYHISNPDGNKSQILVSVS 262

Query: 61  LKFYKELQAHGADELLKRVYGSFLV 85
           LKFYK+LQ HGADEL+KR YG+F V
Sbjct: 263 LKFYKDLQEHGADELIKREYGAFSV 337

 Score = 38.1 bits (87), Expect(2) = 2e-32,   Method: Compositional matrix adjust.
 Identities = 15/29 (51%), Positives = 24/29 (82%)
 Frame = +3

Query: 84  LVNPEPGYNVSLLYDLENLPASKDSIVHQ 112
           LV+PEPGYNVS+++DLE +P + + +V +
Sbjct: 330 LVSPEPGYNVSVVFDLEKVPDNWEEMVEK 416
>07059
          Length = 2866

 Score = 29.6 bits (65), Expect = 1.4,   Method: Compositional matrix adjust.
 Identities = 10/20 (50%), Positives = 15/20 (75%)
 Frame = +1

Query: 247 FRDYLHYHIKCSKAYIHTRM 266
           F +Y+H HI C+K Y++TR 
Sbjct: 217 FLNYIHTHISCTKIYLNTRW 276
>38284
          Length = 293

 Score = 29.6 bits (65), Expect = 1.6,   Method: Composition-based stats.
 Identities = 10/19 (52%), Positives = 15/19 (78%)
 Frame = +3

Query: 247 FRDYLHYHIKCSKAYIHTR 265
           F +Y+H HI C+K Y++TR
Sbjct: 186 FLNYIHTHISCTKIYLNTR 242
>30690
          Length = 470

 Score = 27.3 bits (59), Expect = 6.8,   Method: Compositional matrix adjust.
 Identities = 26/110 (23%), Positives = 46/110 (41%), Gaps = 1/110 (0%)
 Frame = -2

Query: 2   ILLEVNNRIIEETLALKFENAAAGNKPEAVEVTFADFDGVLYHISNPNGDKTKVMVSISL 61
           I    +N I    L LKF +       E  + T  +FD    H  N    K ++++  +L
Sbjct: 334 IYFSFSNNISF*NLVLKFGSLYCNKYNELSDDTIQNFDVYHLHTQNSLVQKNRLVIKENL 155

Query: 62  KFYK-ELQAHGADELLKRVYGSFLVNPEPGYNVSLLYDLENLPASKDSIV 110
            F+K + Q H   + +   +G F  +     N+   Y  +  P++  SI+
Sbjct: 154 GFFKNQKQDHCFRKSVSN-WGDFFSHITKAKNIKSCYICKLAPSTLSSIL 8
>22961
          Length = 1074

 Score = 27.3 bits (59), Expect = 7.9,   Method: Compositional matrix adjust.
 Identities = 10/18 (55%), Positives = 14/18 (77%)
 Frame = -2

Query: 227 LFPRHTNATARDNTINLI 244
           LFP HT+A AR +T+ +I
Sbjct: 281 LFPAHTHACARTHTLTII 228
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|58037267|ref|NP_082235.1| protein disulfide
isomerase-associated 6 [Mus musculus]
         (445 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

04779                                                                 244   5e-65
08504                                                                 137   1e-32
06936                                                                  92   4e-19
03582                                                                  80   1e-15
30644                                                                  55   1e-12
28335                                                                  70   2e-12
18455                                                                  65   4e-11
04510                                                                  60   2e-09
21509                                                                  54   1e-07
15159                                                                  50   1e-06
07257                                                                  50   1e-06
35861                                                                  46   2e-06
18943                                                                  38   0.010
01000                                                                  35   0.071
14392                                                                  34   0.10 
36159                                                                  34   0.12 
38672                                                                  29   3.8  
05794                                                                  28   7.9  
>04779
          Length = 910

 Score =  244 bits (623), Expect = 5e-65,   Method: Compositional matrix adjust.
 Identities = 115/216 (53%), Positives = 151/216 (69%), Gaps = 4/216 (1%)
 Frame = +1

Query: 215 QTKGKVKLAAVDATMNQVLASRYGIKGFPTIKIF----QKGESPVDYDGGRTRSDIVSRA 270
           + KGKVK  A+DAT +Q  A+ Y ++G+PTIK F     +     +Y+GGRT SDI++ A
Sbjct: 1   ELKGKVKFGALDATAHQNKAAEYNVRGYPTIKFFPANSNRASDAQEYNGGRTASDIIAWA 180

Query: 271 LDLFSDNAPPPELLEIINEDIAKKTCEEHQLCVVAVLPHILDTGAAGRNSYLEVLLKLAD 330
            D  ++N PPPEL+EI +E      CE   LCVV+VLPHILD  A  RN +L+ L  L +
Sbjct: 181 SDKHTENVPPPELIEITSESTFDSACEGKPLCVVSVLPHILDCDAKCRNKFLDTLRTLGE 360

Query: 331 KYKKKMWGWLWTEAGAQYELENALGIGGFGYPAMAAINARKMKFALLKGSFSEQGINEFL 390
           K+K+K+WGW W+E G Q  LE +L +GGFGYPAMA +N +KMKF++LKGSFS+ GINEFL
Sbjct: 361 KFKQKLWGWAWSEGGQQPALEESLEVGGFGYPAMAVVNFKKMKFSVLKGSFSKDGINEFL 540

Query: 391 RELSFGRGSTAPVGGGSFPTITPREPWDGKDGELPV 426
           R++S+GRG TAPV G   P I   + WDGKDG+LP 
Sbjct: 541 RDISYGRGHTAPVRGAKKPKIISVDAWDGKDGQLPT 648

 Score = 54.7 bits (130), Expect = 7e-08,   Method: Compositional matrix adjust.
 Identities = 27/56 (48%), Positives = 35/56 (62%), Gaps = 3/56 (5%)
 Frame = +1

Query: 77  LKDVVKVGAVNADKHQSLGGQYGVQGFPTIKIFGANKNKPED---YQGGRTGEAIV 129
           LK  VK GA++A  HQ+   +Y V+G+PTIK F AN N+  D   Y GGRT   I+
Sbjct: 4   LKGKVKFGALDATAHQNKAAEYNVRGYPTIKFFPANSNRASDAQEYNGGRTASDII 171
>08504
          Length = 1225

 Score =  137 bits (344), Expect = 1e-32,   Method: Compositional matrix adjust.
 Identities = 64/121 (52%), Positives = 82/121 (67%)
 Frame = +2

Query: 305 AVLPHILDTGAAGRNSYLEVLLKLADKYKKKMWGWLWTEAGAQYELENALGIGGFGYPAM 364
           AVLP I         +    L       +    GWLW EAGAQ  LE+AL +GGFGYPA+
Sbjct: 8   AVLPQIXTASPPVATTTSRFLRLSGTNTRNTSGGWLWAEAGAQPALEDALEVGGFGYPAL 187

Query: 365 AAINARKMKFALLKGSFSEQGINEFLRELSFGRGSTAPVGGGSFPTITPREPWDGKDGEL 424
           AA+N+RKMK++L++G FSE+GINEFLR+LS+G+GST+P+     P I  R+PWDGKD EL
Sbjct: 188 AAVNSRKMKYSLMRGQFSEKGINEFLRDLSYGKGSTSPIRNAELPKIETRDPWDGKDAEL 367

Query: 425 P 425
           P
Sbjct: 368 P 370
>06936
          Length = 2198

 Score = 92.0 bits (227), Expect = 4e-19,   Method: Compositional matrix adjust.
 Identities = 75/235 (31%), Positives = 113/235 (48%), Gaps = 4/235 (1%)
 Frame = +3

Query: 166 DVVELTDDTFDKNVLDSEDVWMVEFYAPWCGHCKNLEPEWAAAATEVKEQTKGKVKLAAV 225
           DV++L    F ++ ++   + +VEF+APWCGHCK L P++  AAT +  +    V LA V
Sbjct: 147 DVLDLKKSDF-QSTIEKHSLMLVEFFAPWCGHCKKLAPQYELAATALL-KNDPPVPLAKV 320

Query: 226 DATMNQVLASRYGIKGFPTIKIFQKGESPVDYDGGRTRSDIVSRALDLFSDNAPPPELLE 285
           D T    + S+YG+ G+PT+K+F+ GE   DYDG R +  IV     +     P  + L+
Sbjct: 321 DCTEETDVCSKYGVSGYPTLKVFRGGEVNKDYDGPRDKDGIVKYMAKM---AGPTSKELK 491

Query: 286 IINEDIAKKTCEEHQLCVVAVLPHILDTGAAGRNSYLEVLLKLADKYKKKMWGWLWTE-- 343
            + E   +K       CVV        TGA   +   + L K+AD      +G+  +   
Sbjct: 492 SVEE--YEKFLSRDGSCVVGFF-----TGA--NSGMADTLKKVADSEDGLRFGYTTSSEV 644

Query: 344 -AGAQYELENALGIGGFGYPAMA-AINARKMKFALLKGSFSEQGINEFLRELSFG 396
              A+Y+ E  L    F    MA       +KF    G  +   I +FL+E SFG
Sbjct: 645 LEKAKYKDEIVL----FRPQKMANKFEDTAVKFT---GDANSHNIKKFLKEESFG 788

 Score = 84.0 bits (206), Expect = 1e-16,   Method: Compositional matrix adjust.
 Identities = 45/109 (41%), Positives = 66/109 (60%), Gaps = 4/109 (3%)
 Frame = +3

Query: 25  LYSSSDDVIELTPSNFNREVIQSDGLWLVEFYAPWCGHCQRLTPEWKKAATAL---KDVV 81
           L   + DV++L  S+F +  I+   L LVEF+APWCGHC++L P+++ AATAL      V
Sbjct: 129 LAVQASDVLDLKKSDF-QSTIEKHSLMLVEFFAPWCGHCKKLAPQYELAATALLKNDPPV 305

Query: 82  KVGAVNADKHQSLGGQYGVQGFPTIKIF-GANKNKPEDYQGGRTGEAIV 129
            +  V+  +   +  +YGV G+PT+K+F G   NK  DY G R  + IV
Sbjct: 306 PLAKVDCTEETDVCSKYGVSGYPTLKVFRGGEVNK--DYDGPRDKDGIV 446

 Score = 75.5 bits (184), Expect = 4e-14,   Method: Compositional matrix adjust.
 Identities = 40/96 (41%), Positives = 58/96 (60%), Gaps = 2/96 (2%)
 Frame = +3

Query: 174  TFDKNVLDSEDVWMVEFYAPWCGHCKNLEPEWAAAATEVKEQTKGKVKLAAVDATMNQVL 233
             F++ V D E   ++EFYAPWCGHCK L P++   A ++K +   ++ +A +DAT N V 
Sbjct: 1212 NFEELVNDPEKDVLIEFYAPWCGHCKTLAPKYDELAEKLKNEP--EIVIAKMDATANDV- 1382

Query: 234  ASRYGIKGFPTIKIFQKG--ESPVDYDGGRTRSDIV 267
               Y ++GFPT+    KG   SP  Y+GGR  +D V
Sbjct: 1383 PPPYDVRGFPTLYFAPKGSKSSPKKYEGGREVNDFV 1490

 Score = 62.4 bits (150), Expect = 4e-10,   Method: Compositional matrix adjust.
 Identities = 32/87 (36%), Positives = 48/87 (55%), Gaps = 2/87 (2%)
 Frame = +3

Query: 39   NFNREVIQSDGLWLVEFYAPWCGHCQRLTPEWKKAATALKDVVKVGAVNAD-KHQSLGGQ 97
            NF   V   +   L+EFYAPWCGHC+ L P++ + A  LK+  ++     D     +   
Sbjct: 1212 NFEELVNDPEKDVLIEFYAPWCGHCKTLAPKYDELAEKLKNEPEIVIAKMDATANDVPPP 1391

Query: 98   YGVQGFPTIKIF-GANKNKPEDYQGGR 123
            Y V+GFPT+      +K+ P+ Y+GGR
Sbjct: 1392 YDVRGFPTLYFAPKGSKSSPKKYEGGR 1472
>03582
          Length = 1967

 Score = 80.5 bits (197), Expect = 1e-15,   Method: Compositional matrix adjust.
 Identities = 42/88 (47%), Positives = 55/88 (62%)
 Frame = +2

Query: 160 DSSSKKDVVELTDDTFDKNVLDSEDVWMVEFYAPWCGHCKNLEPEWAAAATEVKEQTKGK 219
           D    + V  LT   FD  V ++E V +VEFYAPWCGHCK L PE+A AA  +K++    
Sbjct: 98  DVKQDEGVYVLTTKNFDSFVKENEFV-LVEFYAPWCGHCKALAPEYAKAAQTLKDE-NSD 271

Query: 220 VKLAAVDATMNQVLASRYGIKGFPTIKI 247
           VKLA VDAT+   L    G++G+PT+K 
Sbjct: 272 VKLAKVDATIETSLGENMGVRGYPTLKF 355

 Score = 77.4 bits (189), Expect = 1e-14,   Method: Compositional matrix adjust.
 Identities = 39/80 (48%), Positives = 50/80 (62%), Gaps = 3/80 (3%)
 Frame = +2

Query: 32  VIELTPSNFNREVIQSDGLWLVEFYAPWCGHCQRLTPEWKKAATALKDV---VKVGAVNA 88
           V  LT  NF+   ++ +   LVEFYAPWCGHC+ L PE+ KAA  LKD    VK+  V+A
Sbjct: 119 VYVLTTKNFDS-FVKENEFVLVEFYAPWCGHCKALAPEYAKAAQTLKDENSDVKLAKVDA 295

Query: 89  DKHQSLGGQYGVQGFPTIKI 108
               SLG   GV+G+PT+K 
Sbjct: 296 TIETSLGENMGVRGYPTLKF 355

 Score = 70.1 bits (170), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 35/95 (36%), Positives = 46/95 (48%)
 Frame = +3

Query: 35   LTPSNFNREVIQSDGLWLVEFYAPWCGHCQRLTPEWKKAATALKDVVKVGAVNADKHQSL 94
            L   NF    +       VEFYAPWCGHC++L P W + A    D   V     D   + 
Sbjct: 1140 LVGKNFKEVALDKTKGVFVEFYAPWCGHCKQLAPIWDELADKFTDKADVVIAKMDSTANE 1319

Query: 95   GGQYGVQGFPTIKIFGANKNKPEDYQGGRTGEAIV 129
              +  VQ FPT+K F  + ++  DY G RT +A V
Sbjct: 1320 IEEVKVQSFPTLKYFPKDSDEVIDYNGERTLDAFV 1424

 Score = 67.8 bits (164), Expect = 9e-12,   Method: Compositional matrix adjust.
 Identities = 36/90 (40%), Positives = 50/90 (55%), Gaps = 1/90 (1%)
 Frame = +3

Query: 174  TFDKNVLDSEDVWMVEFYAPWCGHCKNLEPEWAAAATEVKEQTKGKVKLAAVDATMNQVL 233
             F +  LD      VEFYAPWCGHCK L P W   A +  +  K  V +A +D+T N++ 
Sbjct: 1152 NFKEVALDKTKGVFVEFYAPWCGHCKQLAPIWDELADKFTD--KADVVIAKMDSTANEI- 1322

Query: 234  ASRYGIKGFPTIKIFQK-GESPVDYDGGRT 262
                 ++ FPT+K F K  +  +DY+G RT
Sbjct: 1323 -EEVKVQSFPTLKYFPKDSDEVIDYNGERT 1409
>30644
          Length = 845

 Score = 45.8 bits (107), Expect(2) = 1e-12,   Method: Compositional matrix adjust.
 Identities = 41/124 (33%), Positives = 50/124 (40%), Gaps = 6/124 (4%)
 Frame = -1

Query: 82  KVGA----VNADKHQSLG--GQYGVQGFPTIKIFGANKNKPEDYQGGRTGEAIVDAALSA 135
           KVGA    ++ DK    G   QY + GFPT+  F   K K   Y+ G  GE   D  +S 
Sbjct: 335 KVGANLVGIDVDKPHMKGVQAQYNITGFPTLYYFEKGKLK---YRYG--GENNKDGIISW 171

Query: 136 LRQLVKDXXXXXXXXXXXXXXXXXDSSSKKDVVELTDDTFDKNVLDSEDVWMVEFYAPWC 195
           L                        S    +V  L D  FD + L      +V FYAPWC
Sbjct: 170 LSNPKPPEEPKKEAEW---------SEEPSEVAHLEDSNFD-DFLKQHPSVLVMFYAPWC 21

Query: 196 GHCK 199
           GHCK
Sbjct: 20  GHCK 9

 Score = 45.1 bits (105), Expect(2) = 1e-12,   Method: Compositional matrix adjust.
 Identities = 19/52 (36%), Positives = 34/52 (65%), Gaps = 1/52 (1%)
 Frame = -3

Query: 28  SSDDVIELTPSNFNREVIQSD-GLWLVEFYAPWCGHCQRLTPEWKKAATALK 78
           ++ DV+ +   +   ++++ D    LV FYAPWCG+C+R+ P++  AAT +K
Sbjct: 489 TATDVVHIDTDDGLTKLLKKDKSAALVMFYAPWCGYCKRMKPDFAAAATEVK 334

 Score = 55.1 bits (131), Expect(2) = 6e-12,   Method: Compositional matrix adjust.
 Identities = 26/49 (53%), Positives = 35/49 (71%), Gaps = 1/49 (2%)
 Frame = -3

Query: 166 DVVEL-TDDTFDKNVLDSEDVWMVEFYAPWCGHCKNLEPEWAAAATEVK 213
           DVV + TDD   K +   +   +V FYAPWCG+CK ++P++AAAATEVK
Sbjct: 480 DVVHIDTDDGLTKLLKKDKSAALVMFYAPWCGYCKRMKPDFAAAATEVK 334

 Score = 33.1 bits (74), Expect(2) = 6e-12,   Method: Compositional matrix adjust.
 Identities = 15/44 (34%), Positives = 24/44 (54%)
 Frame = -1

Query: 225 VDATMNQVLASRYGIKGFPTIKIFQKGESPVDYDGGRTRSDIVS 268
           VD    + + ++Y I GFPT+  F+KG+    Y G   +  I+S
Sbjct: 305 VDKPHMKGVQAQYNITGFPTLYYFEKGKLKYRYGGENNKDGIIS 174

 Score = 38.1 bits (87), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 17/35 (48%), Positives = 23/35 (65%)
 Frame = -1

Query: 31  DVIELTPSNFNREVIQSDGLWLVEFYAPWCGHCQR 65
           +V  L  SNF+  + Q   + LV FYAPWCGHC++
Sbjct: 107 EVAHLEDSNFDDFLKQHPSV-LVMFYAPWCGHCKK 6
>28335
          Length = 601

 Score = 70.1 bits (170), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 38/90 (42%), Positives = 53/90 (58%), Gaps = 2/90 (2%)
 Frame = -2

Query: 174 TFDKNVLDSEDVWMVEFYAPWCGHCKNLEPEWAAAATEVKEQTKGKVKLAAVDATMNQVL 233
           TFDK V + +   ++EFYAPWCGHC+ LEP++   AT +K++    +  A +DAT N   
Sbjct: 525 TFDKIVNNPKKDVLIEFYAPWCGHCQQLEPKYNELATLLKDEP--DIVXAKIDATANDT- 355

Query: 234 ASRYGIKGFPTIKIFQK--GESPVDYDGGR 261
            + Y +KGFP I    K   E P  Y+G R
Sbjct: 354 PTPYEVKGFPAIYFSPKRFKEFPKKYEGDR 265

 Score = 63.5 bits (153), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 40/105 (38%), Positives = 53/105 (50%), Gaps = 7/105 (6%)
 Frame = -2

Query: 40  FNREVIQSDGLWLVEFYAPWCGHCQRLTPEWKKAATALKDVVKVGAVNAD-KHQSLGGQY 98
           F++ V       L+EFYAPWCGHCQ+L P++ + AT LKD   +     D         Y
Sbjct: 522 FDKIVNNPKKDVLIEFYAPWCGHCQQLEPKYNELATLLKDEPDIVXAKIDATANDTPTPY 343

Query: 99  GVQGFPTIKIFGANKNK--PEDYQGGRTGEA----IVDAALSALR 137
            V+GFP I  F   + K  P+ Y+G R  +A    I   A S LR
Sbjct: 342 EVKGFPAI-YFSPKRFKEFPKKYEGDREVDAMLKYIAREATSELR 211
>18455
          Length = 499

 Score = 65.5 bits (158), Expect = 4e-11,   Method: Compositional matrix adjust.
 Identities = 33/94 (35%), Positives = 55/94 (58%), Gaps = 2/94 (2%)
 Frame = +2

Query: 32  VIELTPSNFNREVIQSDGLWLVEFYAPWCGHCQRLTPEWKKAATAL--KDVVKVGAVNAD 89
           V++LT   F + V  S G   V+F+APWC HCQRL P W++ A AL  +    +  ++  
Sbjct: 146 VVDLTEDTFAKHV--SSGNHFVKFFAPWCSHCQRLAPIWEELAKALIKEPSATISKIDCT 319

Query: 90  KHQSLGGQYGVQGFPTIKIFGANKNKPEDYQGGR 123
           +++S+   + V+G+PT+ ++  +  K E Y G R
Sbjct: 320 QYRSICQDFEVKGYPTL-LWIEDGKKIEKYAGAR 418

 Score = 63.5 bits (153), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 32/95 (33%), Positives = 52/95 (54%)
 Frame = +2

Query: 167 VVELTDDTFDKNVLDSEDVWMVEFYAPWCGHCKNLEPEWAAAATEVKEQTKGKVKLAAVD 226
           VV+LT+DTF K+V  S     V+F+APWC HC+ L P W   A  + ++    +  + +D
Sbjct: 146 VVDLTEDTFAKHV--SSGNHFVKFFAPWCSHCQRLAPIWEELAKALIKEPSATI--SKID 313

Query: 227 ATMNQVLASRYGIKGFPTIKIFQKGESPVDYDGGR 261
            T  + +   + +KG+PT+   + G+    Y G R
Sbjct: 314 CTQYRSICQDFEVKGYPTLLWIEDGKKIEKYAGAR 418
>04510
          Length = 685

 Score = 60.1 bits (144), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 26/53 (49%), Positives = 38/53 (71%)
 Frame = +2

Query: 25  LYSSSDDVIELTPSNFNREVIQSDGLWLVEFYAPWCGHCQRLTPEWKKAATAL 77
           L   + DV++L  S+F +  I+   L LVEF+APWCGHC++L P+++ AATAL
Sbjct: 335 LAVQASDVLDLKKSDF-QSTIEKHSLMLVEFFAPWCGHCKKLAPQYELAATAL 490

 Score = 51.2 bits (121), Expect = 7e-07,   Method: Compositional matrix adjust.
 Identities = 20/47 (42%), Positives = 32/47 (68%)
 Frame = +2

Query: 166 DVVELTDDTFDKNVLDSEDVWMVEFYAPWCGHCKNLEPEWAAAATEV 212
           DV++L    F ++ ++   + +VEF+APWCGHCK L P++  AAT +
Sbjct: 353 DVLDLKKSDF-QSTIEKHSLMLVEFFAPWCGHCKKLAPQYELAATAL 490
>21509
          Length = 754

 Score = 53.9 bits (128), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 35/100 (35%), Positives = 51/100 (51%), Gaps = 1/100 (1%)
 Frame = -3

Query: 170 LTDDTFDKNVLDSEDVWMVEFYAPWCGHCKNLEPEWAAAATEVKEQTKGKV-KLAAVDAT 228
           LT DTFD  V     V +V F        KN    W          ++ K+  +AAVDAT
Sbjct: 713 LTKDTFDTFVSTHSSV-LVMFTPHGADIVKNEASVWRGCC----HHSRAKLGAVAAVDAT 549

Query: 229 MNQVLASRYGIKGFPTIKIFQKGESPVDYDGGRTRSDIVS 268
           ++  L ++Y +KG+PT+K F+ G+   +Y GGR+    VS
Sbjct: 548 LDPELGNKYDVKGYPTLKYFKDGKLAFEYSGGRSSDAFVS 429

 Score = 50.1 bits (118), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 22/44 (50%), Positives = 29/44 (65%)
 Frame = -1

Query: 166 DVVELTDDTFDKNVLDSEDVWMVEFYAPWCGHCKNLEPEWAAAA 209
           DV  LTD TF+  +  +    +V FYAPWCGHCK ++P + AAA
Sbjct: 358 DVNHLTDATFESFIAANRRT-LVMFYAPWCGHCKKMKPAYMAAA 230

 Score = 45.1 bits (105), Expect = 7e-05,   Method: Compositional matrix adjust.
 Identities = 20/45 (44%), Positives = 27/45 (60%)
 Frame = -1

Query: 30  DDVIELTPSNFNREVIQSDGLWLVEFYAPWCGHCQRLTPEWKKAA 74
            DV  LT + F    I ++   LV FYAPWCGHC+++ P +  AA
Sbjct: 361 SDVNHLTDATF-ESFIAANRRTLVMFYAPWCGHCKKMKPAYMAAA 230

 Score = 28.1 bits (61), Expect = 7.1,   Method: Compositional matrix adjust.
 Identities = 12/37 (32%), Positives = 19/37 (51%)
 Frame = -2

Query: 163 SKKDVVELTDDTFDKNVLDSEDVWMVEFYAPWCGHCK 199
           S++ +  ++D     ++     V     YAPWCGHCK
Sbjct: 738 SRERISLVSDQRHV*HIRVHTLVCSCHVYAPWCGHCK 628
>15159
          Length = 1945

 Score = 50.4 bits (119), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 24/76 (31%), Positives = 44/76 (57%), Gaps = 2/76 (2%)
 Frame = +3

Query: 32  VIELTPSNFNREVIQSDGLWLVEFYAPWCGHCQRLTPEWKK--AATALKDVVKVGAVNAD 89
           VI+++ ++   + IQ   L +V+F+A WCG C+ + P+  K       K+ VK+ +V+ D
Sbjct: 81  VIKISSADDFEKAIQGGQLVVVDFHATWCGPCKVIAPKLAKWSEEDRFKETVKIISVDVD 260

Query: 90  KHQSLGGQYGVQGFPT 105
           + + L G+ G+   PT
Sbjct: 261 ELEDLAGEQGISAMPT 308

 Score = 43.5 bits (101), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 29/84 (34%), Positives = 47/84 (55%), Gaps = 1/84 (1%)
 Frame = +3

Query: 162 SSKKDVVELTD-DTFDKNVLDSEDVWMVEFYAPWCGHCKNLEPEWAAAATEVKEQTKGKV 220
           S K  V++++  D F+K +   + V +V+F+A WCG CK + P+ A  + E  ++ K  V
Sbjct: 66  SKKMGVIKISSADDFEKAIQGGQLV-VVDFHATWCGPCKVIAPKLAKWSEE--DRFKETV 236

Query: 221 KLAAVDATMNQVLASRYGIKGFPT 244
           K+ +VD    + LA   GI   PT
Sbjct: 237 KIISVDVDELEDLAGEQGISAMPT 308
>07257
          Length = 1477

 Score = 50.4 bits (119), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 24/78 (30%), Positives = 38/78 (48%)
 Frame = -3

Query: 181  DSEDVWMVEFYAPWCGHCKNLEPEWAAAATEVKEQTKGKVKLAAVDATMNQVLASRYGIK 240
             + D  +V FYAPWC  C N  P + A A     +   ++++ AVD      L +R+G  
Sbjct: 1304 STADCVLVMFYAPWCHFCANTAPHYNALA-----RAFPQLEVLAVDTVHFSNLNARFGTV 1140

Query: 241  GFPTIKIFQKGESPVDYD 258
              P I +F +  S V ++
Sbjct: 1139 AVPNIMLFHQSRSAVRFN 1086

 Score = 44.3 bits (103), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 20/63 (31%), Positives = 31/63 (49%)
 Frame = -3

Query: 52   LVEFYAPWCGHCQRLTPEWKKAATALKDVVKVGAVNADKHQSLGGQYGVQGFPTIKIFGA 111
            LV FYAPWC  C    P +   A A    ++V AV+     +L  ++G    P I +F  
Sbjct: 1286 LVMFYAPWCHFCANTAPHYNALARAFPQ-LEVLAVDTVHFSNLNARFGTVAVPNIMLFHQ 1110

Query: 112  NKN 114
            +++
Sbjct: 1109 SRS 1101
>35861
          Length = 850

 Score = 46.2 bits (108), Expect(2) = 2e-06,   Method: Compositional matrix adjust.
 Identities = 23/70 (32%), Positives = 28/70 (40%)
 Frame = +3

Query: 35  LTPSNFNREVIQSDGLWLVEFYAPWCGHCQRLTPEWKKAATALKDVVKVGAVNADKHQSL 94
           L   NF    +       VEFYAPWCGHC++L P W +     +D   V       H   
Sbjct: 585 LVSKNFKEVALDKSKDVFVEFYAPWCGHCKQLVPIWDELGEKFQDSDDVVIAKNGLHGQR 764

Query: 95  GGQYGVQGFP 104
            G  G    P
Sbjct: 765 SGGGGHPELP 794

 Score = 22.7 bits (47), Expect(2) = 2e-06,   Method: Compositional matrix adjust.
 Identities = 9/22 (40%), Positives = 14/22 (63%)
 Frame = +1

Query: 100 VQGFPTIKIFGANKNKPEDYQG 121
           +Q FPT++IF    ++  DY G
Sbjct: 781 IQSFPTLQIFP*GSDEVVDYNG 846

 Score = 45.8 bits (107), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 21/41 (51%), Positives = 22/41 (53%)
 Frame = +3

Query: 165 KDVVELTDDTFDKNVLDSEDVWMVEFYAPWCGHCKNLEPEW 205
           K V  L    F +  LD      VEFYAPWCGHCK L P W
Sbjct: 570 KPVKVLVSKNFKEVALDKSKDVFVEFYAPWCGHCKQLVPIW 692
>18943
          Length = 1035

 Score = 37.7 bits (86), Expect = 0.010,   Method: Compositional matrix adjust.
 Identities = 24/99 (24%), Positives = 46/99 (46%), Gaps = 16/99 (16%)
 Frame = +2

Query: 60  CGHCQRLT----------PEWKKAATALKD------VVKVGAVNADKHQSLGGQYGVQGF 103
           CG CQ L           P + +A+  + +       V    V+ DK  ++  QY +  +
Sbjct: 170 CGVCQLLCRLVSLQSDSGPTFDEASRKISEEFTQPGKVLFAKVDCDKEVTIASQYRISKY 349

Query: 104 PTIKIFGANKNKPEDYQGGRTGEAIVDAALSALRQLVKD 142
           PT+K+F   +   ++++G R+     DA  + +R+ +KD
Sbjct: 350 PTLKLFRNGQMVKKEFRGQRSA----DALAAFIREELKD 454

 Score = 37.0 bits (84), Expect = 0.015,   Method: Compositional matrix adjust.
 Identities = 22/70 (31%), Positives = 35/70 (50%), Gaps = 12/70 (17%)
 Frame = +2

Query: 195 CGHCKNL----------EPEWAAAATEVKEQ--TKGKVKLAAVDATMNQVLASRYGIKGF 242
           CG C+ L           P +  A+ ++ E+    GKV  A VD      +AS+Y I  +
Sbjct: 170 CGVCQLLCRLVSLQSDSGPTFDEASRKISEEFTQPGKVLFAKVDCDKEVTIASQYRISKY 349

Query: 243 PTIKIFQKGE 252
           PT+K+F+ G+
Sbjct: 350 PTLKLFRNGQ 379

 Score = 29.6 bits (65), Expect = 2.6,   Method: Compositional matrix adjust.
 Identities = 14/44 (31%), Positives = 21/44 (47%)
 Frame = +3

Query: 26  YSSSDDVIELTPSNFNREVIQSDGLWLVEFYAPWCGHCQRLTPE 69
           +  + D + L   N N  + ++D +  V FYA WC   Q L P 
Sbjct: 102 FGHAGDAVALNNDNINTIISRNDVV-FVNFYADWCRFSQILAPR 230

 Score = 29.6 bits (65), Expect = 2.7,   Method: Compositional matrix adjust.
 Identities = 15/45 (33%), Positives = 20/45 (44%)
 Frame = +3

Query: 160 DSSSKKDVVELTDDTFDKNVLDSEDVWMVEFYAPWCGHCKNLEPE 204
           D     D V L +D  +  ++   DV  V FYA WC   + L P 
Sbjct: 99  DFGHAGDAVALNNDNINT-IISRNDVVFVNFYADWCRFSQILAPR 230
>01000
          Length = 1541

 Score = 34.7 bits (78), Expect = 0.071,   Method: Compositional matrix adjust.
 Identities = 14/42 (33%), Positives = 23/42 (54%)
 Frame = -1

Query: 225  VDATMNQVLASRYGIKGFPTIKIFQKGESPVDYDGGRTRSDI 266
            VD T      +   I+G+PT+ +FQ G+   D+ G R+  D+
Sbjct: 1541 VDCTKQSETCNAQSIRGYPTLAVFQNGKRQEDFKGTRSLDDL 1416
>14392
          Length = 468

 Score = 34.3 bits (77), Expect = 0.10,   Method: Compositional matrix adjust.
 Identities = 23/63 (36%), Positives = 35/63 (55%), Gaps = 5/63 (7%)
 Frame = +2

Query: 66  LTPEWKKAATALKD----VVKVGAVNADKHQSLGGQYGVQGFPTIKIFGAN-KNKPEDYQ 120
           LTP +++ A  L+D    +VK+ A   D    +  ++ V+GFPT+     + KNKP  Y 
Sbjct: 2   LTPIYEELAEKLQDEDVAIVKMDATAND----VPPEFNVRGFPTLFWLPKDSKNKPVSYN 169

Query: 121 GGR 123
           GGR
Sbjct: 170 GGR 178
>36159
          Length = 369

 Score = 34.3 bits (77), Expect = 0.12,   Method: Compositional matrix adjust.
 Identities = 11/23 (47%), Positives = 15/23 (65%)
 Frame = -1

Query: 57  APWCGHCQRLTPEWKKAATALKD 79
           APWCGHC++L P W +     +D
Sbjct: 102 APWCGHCKQLVPIWDELGEKFQD 34

 Score = 32.3 bits (72), Expect = 0.36,   Method: Compositional matrix adjust.
 Identities = 16/36 (44%), Positives = 19/36 (52%)
 Frame = -1

Query: 192 APWCGHCKNLEPEWAAAATEVKEQTKGKVKLAAVDA 227
           APWCGHCK L P W       K Q    V +A +D+
Sbjct: 102 APWCGHCKQLVPIWDELGE--KFQDSDDVVIAKMDS 1
>38672
          Length = 730

 Score = 29.3 bits (64), Expect = 3.8,   Method: Compositional matrix adjust.
 Identities = 14/27 (51%), Positives = 18/27 (66%)
 Frame = -3

Query: 164 KKDVVELTDDTFDKNVLDSEDVWMVEF 190
           K D+++L DDT D  VLDS  V M +F
Sbjct: 275 KMDLIDLEDDTIDAEVLDSLAVTMDDF 195
>05794
          Length = 952

 Score = 28.1 bits (61), Expect = 7.9,   Method: Compositional matrix adjust.
 Identities = 16/43 (37%), Positives = 20/43 (46%)
 Frame = -2

Query: 178 NVLDSEDVWMVEFYAPWCGHCKNLEPEWAAAATEVKEQTKGKV 220
           NVL    VW+V F   +C HC        +   E KE T GK+
Sbjct: 396 NVLIGNQVWLVSFIQKYC-HCD-------SQTHETKETTHGKL 292
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31543239|ref|NP_694698.2| microtubule-associated
protein, RP/EB family, member 2 [Mus musculus]
         (326 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

02149                                                                 243   6e-65
28710                                                                  62   3e-10
06997                                                                  62   3e-10
09949                                                                  60   1e-09
11636                                                                  28   4.8  
>02149
          Length = 1269

 Score =  243 bits (621), Expect = 6e-65,   Method: Compositional matrix adjust.
 Identities = 124/257 (48%), Positives = 161/257 (62%)
 Frame = +3

Query: 43  MAVNVYSTSITQETMSRHDIIAWVNDIVSLNYTKVEQLCSGAAYCQFMDMLFPGCISLKK 102
           MAVNV+STS T + +SRHDIIAWVND +  +Y K+E+LC+GAAYCQFMDMLFPG ++LKK
Sbjct: 69  MAVNVHSTSCTSDNLSRHDIIAWVNDSLQTSYGKIEELCTGAAYCQFMDMLFPGTLALKK 248

Query: 103 EKFQAKLEHEYIHNFKLLQASFKRMNVDKVIPVEKLVKGRFQDNLDFIQWFKKFYDANYD 162
            KF  KLEHEYI NFKLLQ +F ++ VDKVIPVE+LVKGRFQDN +F+QWFK+F+DAN  
Sbjct: 249 AKFNTKLEHEYIQNFKLLQNNFGKLGVDKVIPVERLVKGRFQDNFEFVQWFKRFFDANNK 428

Query: 163 GKEYDPVEARQGQDAIPPPDPGEQIFNLPKKSHHANXXXXXXXXXXXXXXXXXXXXXXXX 222
           G +YDP+ AR G+     P  G     L K   +                          
Sbjct: 429 GLDYDPLSARGGE-----PMGGANKGALNKAPSNRTAPPKTRVPPSRTTPARPAANNVRS 593

Query: 223 XXXXXXXXXXXXXDKDLETQVIQLNEQVHSLKLALEGVEKERDFYFGKLREIELLCQEHG 282
                           +E     L  ++  L +  EG+EKERDFYFGKLR+IE++CQEH 
Sbjct: 594 PMSKPTSNHAAGDSPMVE----DLRAELRQLTVEKEGLEKERDFYFGKLRDIEVICQEH- 758

Query: 283 QENDDLVQRLMEVLYAS 299
            E+D  ++ +M++LYA+
Sbjct: 759 -EDDVSMKAIMDILYAT 806
>28710
          Length = 525

 Score = 62.0 bits (149), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 29/61 (47%), Positives = 48/61 (78%), Gaps = 1/61 (1%)
 Frame = -1

Query: 240 ETQVIQ-LNEQVHSLKLALEGVEKERDFYFGKLREIELLCQEHGQENDDLVQRLMEVLYA 298
           +TQ+++ L  ++  + L  EG+EKERDFYFGKLR+IE++CQEH  E+ D ++ ++++LYA
Sbjct: 525 DTQMVEDLRAELRQMNLEKEGLEKERDFYFGKLRDIEIICQEH--EDSDTMKGILDILYA 352

Query: 299 S 299
           +
Sbjct: 351 T 349
>06997
          Length = 583

 Score = 62.0 bits (149), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 31/63 (49%), Positives = 46/63 (73%)
 Frame = +1

Query: 237 KDLETQVIQLNEQVHSLKLALEGVEKERDFYFGKLREIELLCQEHGQENDDLVQRLMEVL 296
           +DL  +V     Q+  L +  EG+EKERDFYFGKLR+IE++CQEH  E+D  ++ +M++L
Sbjct: 76  EDLRAEVCA---QLRQLTVEKEGLEKERDFYFGKLRDIEVICQEH--EDDVSMKAIMDIL 240

Query: 297 YAS 299
           YA+
Sbjct: 241 YAT 249
>09949
          Length = 455

 Score = 60.1 bits (144), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 28/54 (51%), Positives = 42/54 (77%)
 Frame = -1

Query: 246 LNEQVHSLKLALEGVEKERDFYFGKLREIELLCQEHGQENDDLVQRLMEVLYAS 299
           L  ++  L +  EG+EKERDFYFGKLR+IE++CQEH  E+D  ++ +M++LYA+
Sbjct: 440 LRAELRQLTVEKEGLEKERDFYFGKLRDIEVICQEH--EDDVSMKAIMDILYAT 285
>11636
          Length = 819

 Score = 28.1 bits (61), Expect = 4.8,   Method: Compositional matrix adjust.
 Identities = 12/26 (46%), Positives = 19/26 (73%)
 Frame = +1

Query: 246 LNEQVHSLKLALEGVEKERDFYFGKL 271
           L +++ +LK  L+G+EKE DF+  KL
Sbjct: 514 LEKEIXALKKGLQGIEKEVDFFKSKL 591
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|161086971|ref|NP_033927.2| F-actin capping protein
alpha-1 subunit [Mus musculus]
         (286 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

01441                                                                 243   7e-65
06308                                                                  31   0.62 
23871                                                                  28   3.7  
>01441
          Length = 1665

 Score =  243 bits (620), Expect = 7e-65,   Method: Compositional matrix adjust.
 Identities = 111/185 (60%), Positives = 143/185 (77%), Gaps = 2/185 (1%)
 Frame = -1

Query: 103  KEASDPQPEDVDGGLKSWRESCDSALRAYVKDHYSNGFCTVYAKTIDGQQTIIACIESHQ 162
            KE S+ Q  ++D   + WR   +SA+  YV++HY +G  TVY  T DG  T+IACIESHQ
Sbjct: 1665 KEGSEYQAAEIDKRAEPWRAEVESAMTTYVQNHYPHGVATVYGSTADGNITLIACIESHQ 1486

Query: 163  FQPKNFWNGRWRSEWKFTITPP--SAQVVGVLKIQVHYYEDGNVQLVSHKDVQDSVTVSN 220
            FQP+N+WNGRWRS+W  T +    +A+V GVLK QVHYYEDGNVQLVS K+++++V V+ 
Sbjct: 1485 FQPRNYWNGRWRSQWSVTFSESGGTAEVTGVLKAQVHYYEDGNVQLVSSKEIKENVKVTK 1306

Query: 221  EIQTTKEFIKIIESAENEYQTAISENYQTMSDTTFKALRRQLPVTRTKIDWNKILSYKIG 280
            E  T K F+ I+  AE++YQTA+SENYQTMSDTTFKALRRQLPVTR+KIDWNKIL YKIG
Sbjct: 1305 EQATAKAFVNIVSQAESDYQTALSENYQTMSDTTFKALRRQLPVTRSKIDWNKILGYKIG 1126

Query: 281  KEMQN 285
             ++++
Sbjct: 1125 GDLKH 1111
>06308
          Length = 926

 Score = 30.8 bits (68), Expect = 0.62,   Method: Compositional matrix adjust.
 Identities = 15/34 (44%), Positives = 18/34 (52%), Gaps = 2/34 (5%)
 Frame = -3

Query: 62  FTPVKIEGYDDQVLITEHGDL--GNSRFLDPRNQ 93
           F P+   G+DD  +I  H DL    SRFL P  Q
Sbjct: 456 FNPLPTNGHDDDAMIALHSDL*YCXSRFLKPSVQ 355
>23871
          Length = 890

 Score = 28.1 bits (61), Expect = 3.7,   Method: Compositional matrix adjust.
 Identities = 14/31 (45%), Positives = 16/31 (51%), Gaps = 2/31 (6%)
 Frame = +2

Query: 62  FTPVKIEGYDDQVLITEHGDL--GNSRFLDP 90
           F P+   G+DD   I  H DL    SRFL P
Sbjct: 461 FNPLPTNGHDDDATIALHSDL*YCRSRFLKP 553
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|47777351|ref|NP_034272.1| Eph receptor B2 [Mus
musculus]
         (986 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

17300                                                                 192   8e-65
21808                                                                 221   1e-57
06405                                                                 214   2e-55
11780                                                                 110   6e-41
04852                                                                 164   2e-40
09007                                                                 159   4e-39
14116                                                                 145   1e-34
22005                                                                 117   8e-32
08294                                                                 122   4e-31
20640                                                                 125   9e-29
07291                                                                 116   5e-26
18996                                                                 112   6e-25
07940                                                                 110   2e-24
01718                                                                 107   2e-23
17253                                                                  99   7e-21
14477                                                                  92   1e-18
13305                                                                  84   4e-16
12721                                                                  84   4e-16
17637                                                                  83   5e-16
07833                                                                  83   6e-16
18921                                                                  79   8e-15
00300                                                                  77   4e-14
14126                                                                  69   1e-11
01756                                                                  68   1e-11
19301                                                                  66   6e-11
27546                                                                  65   1e-10
14420                                                                  64   4e-10
09606                                                                  61   2e-09
18484                                                                  61   2e-09
21079                                                                  60   3e-09
01060                                                                  59   1e-08
29581                                                                  59   1e-08
15910                                                                  57   5e-08
13066                                                                  57   5e-08
19094                                                                  56   6e-08
04591                                                                  56   6e-08
07836                                                                  56   7e-08
00715                                                                  55   2e-07
13212                                                                  54   2e-07
12672                                                                  54   3e-07
17975                                                                  53   7e-07
31885                                                                  53   8e-07
30755                                                                  52   2e-06
01707                                                                  51   3e-06
19544                                                                  48   2e-05
01966                                                                  48   2e-05
26711                                                                  47   5e-05
17806                                                                  47   5e-05
04138                                                                  46   7e-05
03240                                                                  45   1e-04
25550                                                                  45   1e-04
19761                                                                  44   2e-04
02638                                                                  44   3e-04
01392                                                                  43   6e-04
34970                                                                  43   8e-04
11185                                                                  42   0.001
17679                                                                  40   0.004
27287                                                                  39   0.007
12786                                                                  39   0.012
32264                                                                  39   0.013
16708                                                                  37   0.027
26560                                                                  37   0.034
27405                                                                  37   0.056
07218                                                                  36   0.063
38046                                                                  34   0.24 
15741                                                                  33   0.38 
31489                                                                  33   0.73 
28638                                                                  33   0.76 
26039                                                                  32   1.2  
30103                                                                  32   1.5  
21210                                                                  32   1.6  
33147                                                                  32   1.8  
07933                                                                  32   1.8  
37602                                                                  31   2.0  
09206                                                                  30   3.5  
21433                                                                  30   4.5  
07945                                                                  30   5.1  
11667                                                                  30   7.0  
>17300
          Length = 480

 Score =  192 bits (488), Expect(2) = 8e-65,   Method: Compositional matrix adjust.
 Identities = 88/117 (75%), Positives = 102/117 (87%)
 Frame = +1

Query: 730 IAAGMKYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSALGGKIP 789
           I++GM  LADM YVHRDLAARNILVN  LVCKV+DFGLSR +E DT++  YT+  GGKIP
Sbjct: 1   ISSGMGXLADMGYVHRDLAARNILVNEILVCKVADFGLSREIESDTTEGAYTTK-GGKIP 177

Query: 790 IRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIEQDYRLP 846
           +RWTAPEAI YRKFTSASDVWS+G+VMWEVMSYGERPYW+ +NQDVI A+E+ YRLP
Sbjct: 178 VRWTAPEAIAYRKFTSASDVWSFGVVMWEVMSYGERPYWNWSNQDVIKAVEKGYRLP 348

 Score = 74.7 bits (182), Expect(2) = 8e-65,   Method: Composition-based stats.
 Identities = 30/44 (68%), Positives = 34/44 (77%)
 Frame = +2

Query: 847 PPMDCPSALHQLMLDCWQKDRNHRPKFGQIVNTLDKMIRNPNSL 890
           P MDCP ALHQLMLD WQK+R+HRPK   +V TLDK+IR P  L
Sbjct: 347 PSMDCPEALHQLMLDAWQKERSHRPKMSMVVKTLDKLIRAPELL 478
>21808
          Length = 1011

 Score =  221 bits (563), Expect = 1e-57,   Method: Compositional matrix adjust.
 Identities = 106/224 (47%), Positives = 146/224 (65%)
 Frame = +1

Query: 650 VAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDS 709
           VAIKTLKSG  +   +DFL+EA IM +  HP +I L  V T+  P+ IITE M+NGSL  
Sbjct: 28  VAIKTLKSGTMDP--KDFLAEAQIMKKLRHPKLIQLYAVCTQDDPIFIITELMKNGSLLE 201

Query: 710 FLRQNDGQFTVIQLVGMLRGIAAGMKYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSR 769
           FL+       +  L+ +   IA GM YL   NY+HRDLAARNILV+ N   K++DFGL+R
Sbjct: 202 FLQGKGRVLKLPALIDIGAQIACGMAYLESQNYIHRDLAARNILVSDNNTVKIADFGLAR 381

Query: 770 FLEDDTSDPTYTSALGGKIPIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWD 829
            +++D     Y + +G + PI+WTAPEA  Y +FT  SDVWS+GI++ E ++YG  PY  
Sbjct: 382 VIKEDE----YEARVGARFPIKWTAPEAANYNRFTIKSDVWSFGILLTETVTYGRVPYPG 549

Query: 830 MTNQDVINAIEQDYRLPPPMDCPSALHQLMLDCWQKDRNHRPKF 873
           MTN +V++ +E  YR+P P  CP  L+ +ML+CW+K+   RP  
Sbjct: 550 MTNAEVLHQVEHGYRMPCPPGCPKPLYDIMLECWRKEEMERPHL 681
>06405
          Length = 1965

 Score =  214 bits (544), Expect = 2e-55,   Method: Compositional matrix adjust.
 Identities = 108/271 (39%), Positives = 166/271 (61%), Gaps = 1/271 (0%)
 Frame = +1

Query: 615 EIDISCVKIEQVIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEASIM 674
           EI+ + + ++  +G G++G+V     K   K    VA+KTLK         DFL EA+IM
Sbjct: 247 EIERTEIAMKHRLGGGQYGDVYEAMWKRYNK---IVAVKTLKEDTMALN--DFLEEAAIM 411

Query: 675 GQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDSFLRQNDGQFT-VIQLVGMLRGIAAG 733
            +  HPN++ L GV T+  P  I+TEFM +G+L  +LR +  +      L+ M   IA+G
Sbjct: 412 KEMKHPNLVQLLGVCTREPPFYIVTEFMPHGNLLDYLRSSTREENGPTALMYMATQIASG 591

Query: 734 MKYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSALGGKIPIRWT 793
           M YL   N++HRDLAARN LV  + + KV+DFGL+R ++DDT    YT+ +G K PI+WT
Sbjct: 592 MAYLETKNFIHRDLAARNCLVADSNMVKVADFGLARLMKDDT----YTAHIGAKFPIKWT 759

Query: 794 APEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIEQDYRLPPPMDCPS 853
           APE + + +F++ SD+W++G+++WE+ +YG  PY  +   +V + +E+ YR+  P   P+
Sbjct: 760 APEGLAFNRFSTRSDIWAFGVLLWELATYGMSPYPGVELTEVYHLLERGYRMERPPGTPA 939

Query: 854 ALHQLMLDCWQKDRNHRPKFGQIVNTLDKMI 884
            ++ LML CWQ D   RP F +I   L+ M 
Sbjct: 940 DVYILMLKCWQWDPKDRPTFKEIHFLLENMF 1032
>11780
          Length = 1713

 Score =  110 bits (276), Expect(2) = 6e-41,   Method: Compositional matrix adjust.
 Identities = 73/183 (39%), Positives = 101/183 (55%), Gaps = 1/183 (0%)
 Frame = +3

Query: 621 VKIEQVIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEASIMGQFDHP 680
           ++I + IG G+FG+V  G       R   VAIK LK    ++  + FL EAS+M    H 
Sbjct: 603 LEIGEAIGKGDFGDVYKGMY-----RGQPVAIKQLKD--KDRGEQSFLQEASVMTSLRHD 761

Query: 681 NVIHLEGVVTKSTPVMIITEFMENGSLDSFLR-QNDGQFTVIQLVGMLRGIAAGMKYLAD 739
           N++ L GVV   T + ++TEFM  G+L  +LR +     T    +       A M+YL  
Sbjct: 762 NLVRLIGVVLGET-IFLVTEFMGKGNLVEYLRSRGRSVITKKDQINFATDTCAAMEYLES 938

Query: 740 MNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSALGGKIPIRWTAPEAIQ 799
              VHRDLAARN+LV+ +   KVSDFGL++F      D + TS    K PI+WTAPEA++
Sbjct: 939 KRLVHRDLAARNVLVHDDGKAKVSDFGLAKF-----GDFSQTSV---KFPIKWTAPEALR 1094

Query: 800 YRK 802
             K
Sbjct: 1095ENK 1103

 Score = 76.3 bits (186), Expect(2) = 6e-41,   Method: Compositional matrix adjust.
 Identities = 32/80 (40%), Positives = 50/80 (62%)
 Frame = +1

Query: 802  KFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIEQDYRLPPPMDCPSALHQLMLD 861
            KFTS SD+WS+GI++WE+ S+G  PY  +   DV+  +E+ YR+  P  CP  ++ +M  
Sbjct: 1102 KFTSKSDMWSFGILLWEIYSFGRVPYPRIPLTDVVMHVERGYRMEAPEGCPPEIYSIMKQ 1281

Query: 862  CWQKDRNHRPKFGQIVNTLD 881
             W+ D N RP F  ++  L+
Sbjct: 1282 AWELDPNERPTFKSVLARLN 1341
>04852
          Length = 1462

 Score =  164 bits (414), Expect = 2e-40,   Method: Compositional matrix adjust.
 Identities = 93/264 (35%), Positives = 145/264 (54%), Gaps = 29/264 (10%)
 Frame = +1

Query: 650 VAIKTLKSGYTEKQRRDFLSEASIMGQF----DHPNVIHLEGVVTKSTPVMIITEFMENG 705
           VA+K L+   T  + +DF+ E  +M        H N+++  G  T+  P+ +I EF +NG
Sbjct: 28  VAVKMLRDIVTAVEEQDFVQELQVMKAVKKMGSHINIVNFLGCCTQGGPLWVIVEFAKNG 207

Query: 706 SLDSFLR---------------QNDGQFT------VIQLVGMLR---GIAAGMKYLADMN 741
           +L  FL                Q+ G +T      VI+   +L     IA GM++LA   
Sbjct: 208 NLRDFLESCRDGINGYGKFVSPQDPGWYTKTPGGHVIRRKNLLSYAFQIARGMEFLASRK 387

Query: 742 YVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSALGGKIPIRWTAPEAIQYR 801
            +HRDLAARN+LV    V K++DFGLSR     T D  Y    GG++P++W APEA+   
Sbjct: 388 CIHRDLAARNVLVTEEHVLKIADFGLSR-----TGD-YYKKRSGGRLPVKWMAPEALFDM 549

Query: 802 KFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIEQD-YRLPPPMDCPSALHQLML 860
           ++T+ SDVWS+G+V+WE+ S G  PY  + N+++ + +  D YR+P P      L+ +M 
Sbjct: 550 RYTTKSDVWSFGVVLWEIFSLGGMPYASIPNEELYSKLLDDAYRMPRPELASGNLYAIME 729

Query: 861 DCWQKDRNHRPKFGQIVNTLDKMI 884
            CW    + RP+F Q+V  +D+++
Sbjct: 730 RCWLNRPSDRPEFSQLVGHIDRLL 801
>09007
          Length = 1440

 Score =  159 bits (403), Expect = 4e-39,   Method: Compositional matrix adjust.
 Identities = 94/290 (32%), Positives = 152/290 (52%), Gaps = 7/290 (2%)
 Frame = -1

Query: 616 IDISCVKIEQVIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEASIMG 675
           I   CV + + +G G FG V           ++ VA+K L      K  ++FL E +IM 
Sbjct: 888 ISKDCVALSKSLGQGHFGTVRQAIWTAESGEKVQVAVKCLSKDKIHKDGQEFLKETAIMQ 709

Query: 676 QFDHPNVIHLEGVVTKS-TPVMIITEFMENGSLDSFLRQNDGQ--FTVIQLVGMLRGIAA 732
             DH N++ + GVV  +   +M++TE     SL   +++   +  F+V +L    + +  
Sbjct: 708 MLDHENIVRVYGVVMDNGADIMLVTELAPMRSLLECVKEVSARVDFSVPRLCDFSQQVCD 529

Query: 733 GMKYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSALGGKIPIRW 792
           GM YL     VHRDLAARNIL+ S    K+SD G+S  L            +  +  + W
Sbjct: 528 GMSYLESKRLVHRDLAARNILLFSKSKVKISDVGVSGALGAGKEYYQSQQTIHLQNAVAW 349

Query: 793 TAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIE--QDYRLPPPMD 850
            APE+ +   F+SASDVW++G+++WE  ++G +P+  +  Q ++ A++  Q  RL  P  
Sbjct: 348 CAPESFRNLCFSSASDVWAFGVLLWEFFTHGFQPWAGLNGQQIMEAVDAPQSQRLEQPDL 169

Query: 851 CPSALHQLMLDCWQKDRNHRPKFGQIVNTLDKMIRNPNSLKAM--APLSS 898
           CP   + +ML CW+++   RP F Q+  TL ++   P  +KA+  AP S+
Sbjct: 168 CPKEYYAVMLKCWEQEPQRRPTFSQLFLTLPQI--RPIQVKAVKDAPSST 25
>14116
          Length = 1017

 Score =  145 bits (365), Expect = 1e-34,   Method: Compositional matrix adjust.
 Identities = 83/226 (36%), Positives = 133/226 (58%), Gaps = 5/226 (2%)
 Frame = -1

Query: 603 EDPNEAVREFAKEIDISCVKIEQVIGAGEFGEVCSGHLKLPGKR-EIFVAIKTLKSGY-T 660
           ED  + +   +  ID   + + + IG G FG V  G L LP ++ +I VA+KTL +    
Sbjct: 684 EDMMKLIENESLLIDREFLTMGEEIGKGNFGCVKRGFLTLPEQKGDILVAVKTLHNNNPR 505

Query: 661 EKQRRDFLSEASIMGQFDHPNVIHLEGVVTKSTPV-MIITEFMENGSLDSFLRQNDGQFT 719
           E + + FL EA IM  F H NV+ L G+      + +++  FM++G L +++R +  Q T
Sbjct: 504 EIELQSFLQEALIMKDFHHSNVLTLIGICLNLDDMPLVVLPFMKHGDLLTYIRDDQHQPT 325

Query: 720 VIQLVGMLRGIAAGMKYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPT 779
           +  L+     IA GM YLA + +VHRDLAARN +++ +   KV+DFGL+R    D  +  
Sbjct: 324 IKDLIMYGVDIARGMDYLAGLKFVHRDLAARNCMLDEDFHVKVADFGLAR----DIYEKE 157

Query: 780 YTSALG--GKIPIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYG 823
           Y S+     K+P++W A E+++   + S +DVWSYG+V+WE+++ G
Sbjct: 156 YYSSENKKAKLPVKWMALESLEKGNYDSKTDVWSYGVVLWELLTRG 19
>22005
          Length = 873

 Score =  117 bits (294), Expect(2) = 8e-32,   Method: Compositional matrix adjust.
 Identities = 84/247 (34%), Positives = 112/247 (45%), Gaps = 53/247 (21%)
 Frame = +1

Query: 627 IGAGEFGEVCSGHLKLPGKREIFVAI----------KTLKSGYTEKQRRDFLSEASIMGQ 676
           IG G FG V    LK  G   +   +          K LK   +E  + DF  EAS+M  
Sbjct: 7   IGQGAFGRV--SKLKFLGLASLVGELIPEKRP*LL*KMLKEDASEDLQSDFEREASLMAD 180

Query: 677 FDHPNVIHLEGVVTKSTPVMIITEFMENGSLDSFLR------------------------ 712
           FDHPN++ L GV     P+ ++ EFM  G L+ FLR                        
Sbjct: 181 FDHPNIVKLLGVCAIGKPMCLLFEFMSKGDLNDFLRLCSPENYNLPVSRSQNLVVDLEDG 360

Query: 713 ----------QNDGQFTVIQLVGML---------RGIAAGMKYLADMNYVHRDLAARNIL 753
                     + D Q       GML         + I+AGM YLA  +YVHRDLA R + 
Sbjct: 361 LRVEVEAEECEKDTQSEDRDCSGMLXTKDQLYISQQISAGMAYLAQKDYVHRDLATRTVX 540

Query: 754 VNSNLVCKVSDFGLSRFLEDDTSDPTYTSALGGKIPIRWTAPEAIQYRKFTSASDVWSYG 813
             +     +SDFGL+R +    S   Y  +    IPIRW   EAI Y KF++ SDVWS+G
Sbjct: 541 SRTT*S*-ISDFGLARSVH---SVDYYRGSEQDAIPIRWMPLEAILYSKFSTQSDVWSFG 708

Query: 814 IVMWEVM 820
           +V+WE++
Sbjct: 709 VVLWEIL 729

 Score = 38.9 bits (89), Expect(2) = 8e-32,   Method: Composition-based stats.
 Identities = 13/45 (28%), Positives = 28/45 (62%)
 Frame = +3

Query: 821 SYGERPYWDMTNQDVINAIEQDYRLPPPMDCPSALHQLMLDCWQK 865
           ++  +PY+ +T+++V+N ++    L  P   P  +++LM  CWQ+
Sbjct: 729 AFALQPYYGLTHEEVVNYVKAGKILEQPTKTPHQVYELMKQCWQR 863
>08294
          Length = 1849

 Score =  122 bits (305), Expect(2) = 4e-31,   Method: Compositional matrix adjust.
 Identities = 67/212 (31%), Positives = 111/212 (52%), Gaps = 11/212 (5%)
 Frame = +2

Query: 680  PNVIHLEGVVTKSTPVMIITEFMENGSLDSFL---RQNDGQ--------FTVIQLVGMLR 728
            PN++H  GV  ++ P  +ITE+ + G L  FL   R ++G+          + Q +GM +
Sbjct: 887  PNIVHFMGVCREAEPHFLITEYCDWGDLKQFLLATRNDNGRGRGTRVPALALSQKLGMGQ 1066

Query: 729  GIAAGMKYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSALGGKI 788
             +AAGM+ L++   VH DLAARN+L+ S +  KV+   LS     D     Y       +
Sbjct: 1067 QVAAGMEALSNQGLVHGDLAARNVLLTSRMQLKVARPALS----GDVYASEYYPLHQRLV 1234

Query: 789  PIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIEQDYRLPPP 848
            P+RW  PE +     T+  DVW++G+ +WEV+   + PY  M++++V+ +++        
Sbjct: 1235 PLRWLPPEGVLEDSATTCGDVWAFGVFLWEVLQLADLPYRLMSDEEVLRSLQHSQAALDS 1414

Query: 849  MDCPSALHQLMLDCWQKDRNHRPKFGQIVNTL 880
             D P AL  L+  C  +  + RP F +I + L
Sbjct: 1415 PDAPPALLSLLQRCTAQQPSQRPPFSEICSVL 1510

 Score = 32.3 bits (72), Expect(2) = 4e-31,   Method: Compositional matrix adjust.
 Identities = 19/59 (32%), Positives = 32/59 (54%), Gaps = 1/59 (1%)
 Frame = +3

Query: 625 QVIGAG-EFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNV 682
           +V GAG E+  V        G +E+ V +K+L S   E++ RDF +E  +  + +HP +
Sbjct: 747 RVFGAGQEWARV--------GDQELLVVVKSLLS-KGERETRDFYAEMDLFARMEHPTL 896
>20640
          Length = 1492

 Score =  125 bits (314), Expect = 9e-29,   Method: Compositional matrix adjust.
 Identities = 63/163 (38%), Positives = 95/163 (58%), Gaps = 4/163 (2%)
 Frame = +1

Query: 742 YVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSALGGKIPIRWTAPEAIQYR 801
           YVHRDLA RN LV  +LV K+SDFGL+R +    S   Y  +    IPIRW   EAI Y 
Sbjct: 7   YVHRDLATRNCLVGHDLVVKISDFGLARSVH---SVDYYRGSEHDAIPIRWMPLEAILYN 177

Query: 802 KFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIEQDYRLPPPMDCPSALHQLMLD 861
           KF++ SDVWS+G+V+WE+ ++  +PY+ +T+++V+  +++   L  P   P  +++LM  
Sbjct: 178 KFSTQSDVWSFGVVLWEIFAFALQPYYGLTHEEVVRFVKEGKVLACPERTPPPMYELMKQ 357

Query: 862 CWQKDRNHRPKFGQIVNTLDKMI----RNPNSLKAMAPLSSGI 900
           CW +    RP F  +  TL+ M     +N   LK    L + +
Sbjct: 358 CWHRRPATRPSFHTLHKTLENMHSKYEKNEVKLKKWCDLEAAV 486
>07291
          Length = 833

 Score =  116 bits (290), Expect = 5e-26,   Method: Compositional matrix adjust.
 Identities = 57/166 (34%), Positives = 97/166 (58%), Gaps = 3/166 (1%)
 Frame = +1

Query: 718 FTVIQLVGMLRGIAAGMKYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDD--- 774
            TV+QL+   R IA GM YL ++  VHR+LAARN +V  +   ++SD+G++  L      
Sbjct: 40  LTVVQLLDFGRQIADGMAYLQEVKVVHRNLAARNCIVTEDGRLQLSDYGVTGSLFPQSYY 219

Query: 775 TSDPTYTSALGGKIPIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQD 834
           T+D +    L     ++W APE I    F+S SDVW++G+V+WE+++ G  PY D+ N  
Sbjct: 220 TADDSPARDL-----VKWMAPETIDNFHFSSKSDVWAFGVVLWELLTRGITPYPDVENSS 384

Query: 835 VINAIEQDYRLPPPMDCPSALHQLMLDCWQKDRNHRPKFGQIVNTL 880
           ++  +++ +R+  P   P  ++++M  CW +    RP F ++ + L
Sbjct: 385 LLPYLKEGHRMKKPKQSPEPVYEMMTACWNESPEQRPDFAELNDQL 522
>18996
          Length = 491

 Score =  112 bits (281), Expect = 6e-25,   Method: Compositional matrix adjust.
 Identities = 61/145 (42%), Positives = 89/145 (61%), Gaps = 5/145 (3%)
 Frame = +2

Query: 743 VHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSALGGKIPIRWTAPEAIQYRK 802
           +HRDLAARNILV+ + V K+SDFGL++F     +D  Y       IPI+W +PEAI+  K
Sbjct: 2   IHRDLAARNILVDRSCV-KISDFGLAQFA---NADGYYYGISQRDIPIKWYSPEAIETCK 169

Query: 803 FTSASDVWSYGIVMWEVMSYGERPYW----DMTNQDVINAIEQDYRLPPPMDCPSALH-Q 857
           F+S SDVWSYG+ ++E+ S GE P      D+T ++ +N + +  RLP P  C   ++ +
Sbjct: 170 FSSYSDVWSYGVTLFEMFSRGEIPNLLPGHDLTQEEFLNRLRKGERLPKPELCSDFVYSE 349

Query: 858 LMLDCWQKDRNHRPKFGQIVNTLDK 882
           LM  CW +    RP F QI+  + +
Sbjct: 350 LMRPCWHEMPKSRPTFHQIIQIIAR 424
>07940
          Length = 1336

 Score =  110 bits (276), Expect = 2e-24,   Method: Compositional matrix adjust.
 Identities = 51/115 (44%), Positives = 74/115 (64%)
 Frame = -3

Query: 723 LVGMLRGIAAGMKYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTS 782
           L+     +A GM+YLA    +HRDLAARN+LV    V K++DFGL+R L+       Y  
Sbjct: 341 LISYAYQVARGMEYLASKQCIHRDLAARNVLVAEEYVLKIADFGLTRNLQQFD---YYRK 171

Query: 783 ALGGKIPIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVIN 837
              G++P++W APEA+  RK+TS SDVWSYG+++WE+ + G  PY  +  +D+ N
Sbjct: 170 TTDGRLPVKWMAPEALFDRKYTSKSDVWSYGVLLWEIFTLGGNPYPSVPVEDLFN 6
>01718
          Length = 959

 Score =  107 bits (268), Expect = 2e-23,   Method: Compositional matrix adjust.
 Identities = 78/286 (27%), Positives = 125/286 (43%), Gaps = 6/286 (2%)
 Frame = +3

Query: 607 EAVREFAKEIDISCVKIEQVIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRD 666
            AV    +  D  C KI    GAG F EV     ++ G+      +  LK       R +
Sbjct: 123 HAVSALTRLDDFICEKI----GAGFFSEVFKVTHRITGQ------VMALKMNTMTSNRHN 272

Query: 667 FLSEASIMGQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDSFLRQNDGQFTVIQLVGM 726
            L E  ++ +  H N++   GV      +  +TE++ +G+L+  L + D +    Q + +
Sbjct: 273 MLREVQLLNRLQHANILRFMGVCVHEGQLHALTEYIPSGNLEQLLEKKDEELPWTQRIQL 452

Query: 727 LRGIAAGMKYLADMNYVHRDLAARNILV----NSNLVCKVSDFGLSRFLEDDTSDPTYTS 782
             G+A G+ YL    ++HRDL ++NIL+    N      ++DFGL+        DP    
Sbjct: 453 TLGLARGLDYLHSTRFIHRDLTSKNILIRREDNHGYHAVIADFGLA----TKIPDPLDKE 620

Query: 783 ALGGKIPIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIEQD 842
            L       W APE +    +   +D++S GI+M E+ +   R   D      +N    D
Sbjct: 621 KLPTVGSPYWMAPEVLNGHFYNERADLFSVGIIMCEITA---RIPADPDIMPRMNNFGVD 791

Query: 843 YRLPPPMD--CPSALHQLMLDCWQKDRNHRPKFGQIVNTLDKMIRN 886
           Y     M   CP    QL   C Q D   RP+  +I+  L+K+ +N
Sbjct: 792 YVALSEMISYCPLDYLQLAFKCCQVDPQKRPRGVEIIEWLEKIFKN 929
>17253
          Length = 483

 Score = 99.4 bits (246), Expect = 7e-21,   Method: Composition-based stats.
 Identities = 59/155 (38%), Positives = 82/155 (52%), Gaps = 12/155 (7%)
 Frame = -1

Query: 650 VAIKTLKSGYTEKQRRDFLSEASIMGQFD-HPNVIHLEGVVTKSTPVMIITEFMENGSLD 708
           VA+KT     T+ ++ +FL E SIM +   HPNV+   G  T S P +I+ EF  +G L 
Sbjct: 459 VAVKTHNEAATDAEKSEFLRELSIMRKLPRHPNVVSFMGCCTMSDPALILMEFCCHGDLL 280

Query: 709 SFLRQNDGQFTVI-----------QLVGMLRGIAAGMKYLADMNYVHRDLAARNILVNSN 757
           SFLR+     TV                    +A GM ++A+   VHRD+AARN+L++  
Sbjct: 279 SFLRKRRPDRTVFLTSTANDLTARDFFSFALHVARGMAHVANNKIVHRDVAARNVLISER 100

Query: 758 LVCKVSDFGLSRFLEDDTSDPTYTSALGGKIPIRW 792
            VCKVSDFGLSR + D   +  Y       +P+RW
Sbjct: 99  NVCKVSDFGLSRRVGD--QNDVYEIVSRRPLPLRW 1
>14477
          Length = 493

 Score = 92.0 bits (227), Expect = 1e-18,   Method: Composition-based stats.
 Identities = 55/154 (35%), Positives = 89/154 (57%), Gaps = 1/154 (0%)
 Frame = -1

Query: 624 EQVIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQ-RRDFLSEASIMGQFDHPNV 682
           E  +GAG FG V  G  +L   REI VAIK LK+   +   + + + EA +M + DH ++
Sbjct: 475 ELKLGAGNFGSVMKGVCRL-DDREIPVAIKVLKNADLDPSVQSELIKEAEVMKKMDHMHI 299

Query: 683 IHLEGVVTKSTPVMIITEFMENGSLDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLADMNY 742
           + L G+    T +M++ E  + G L+ FL +N     +  ++ ++  ++ GM+YL    +
Sbjct: 298 VRLIGLCEGET-MMLVLELAKLGPLNKFLPKNK-HLPLWNILELMWQVSQGMEYLEANKF 125

Query: 743 VHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTS 776
           VHRDLAARNIL+      K+SDFG+S+ L  + +
Sbjct: 124 VHRDLAARNILLCDEHFAKISDFGMSKTLSRENN 23
>13305
          Length = 549

 Score = 83.6 bits (205), Expect = 4e-16,   Method: Compositional matrix adjust.
 Identities = 34/98 (34%), Positives = 56/98 (57%)
 Frame = +2

Query: 787 KIPIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIEQDYRLP 846
           ++PIRW A E++    +T+ SDVWS+G+V+WE+ + G  PY     Q +   ++  YRL 
Sbjct: 8   RVPIRWMAVESLFNNTYTTQSDVWSFGVVLWEIFTLGGTPYSSTDTQQLFAFLKDGYRLK 187

Query: 847 PPMDCPSALHQLMLDCWQKDRNHRPKFGQIVNTLDKMI 884
            P  C    + +ML CW ++   RP F ++   L +M+
Sbjct: 188 RPKLCDQNTYAMMLQCWNENAQRRPTFPELCGRLQRML 301
>12721
          Length = 821

 Score = 83.6 bits (205), Expect = 4e-16,   Method: Compositional matrix adjust.
 Identities = 61/223 (27%), Positives = 109/223 (48%), Gaps = 1/223 (0%)
 Frame = +1

Query: 627 IGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFL-SEASIMGQFDHPNVIHL 685
           IG G  G VC    +  G++   +A+K  K    ++QRR+ L +E  +M  + HPN++ +
Sbjct: 112 IGEGSTGIVCIATSR-DGRQ---MAVK--KMDLRKQQRRELLFNEVVVMRDYHHPNIVEM 273

Query: 686 EGVVTKSTPVMIITEFMENGSLDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLADMNYVHR 745
                 +  + ++ EFME G+L   +  N  +   +Q+  + R     + +L     +HR
Sbjct: 274 YNSYLVNDELWVVMEFMEGGALTDIVTNN--RMDEVQIATVCRACLKALAFLHANGVIHR 447

Query: 746 DLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSALGGKIPIRWTAPEAIQYRKFTS 805
           D+ + +IL++ +   K+ DFG   F    T D     +L G     W APE I    +  
Sbjct: 448 DIKSDSILLSHDGKVKLXDFG---FCAQVTQDLQKRKSLVGT--PYWMAPEVISRLPYGP 612

Query: 806 ASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIEQDYRLPPP 848
             D+WS GI++ E++   E P++   N+  + A+ +   +PPP
Sbjct: 613 EVDIWSLGIMVMEMID-AEPPFF---NEPPLQAMRRIRDMPPP 729
>17637
          Length = 447

 Score = 83.2 bits (204), Expect = 5e-16,   Method: Compositional matrix adjust.
 Identities = 42/127 (33%), Positives = 68/127 (53%), Gaps = 1/127 (0%)
 Frame = +1

Query: 751 NILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSALGGKI-PIRWTAPEAIQYRKFTSASDV 809
           N +++  L  K++D  LSR    D     Y     G+  PI+W + EA+Q   +   SDV
Sbjct: 1   NCVIDDQLRVKLTDSALSR----DLFSGDYNCLGDGEYRPIKWLSLEALQKSHYNEGSDV 168

Query: 810 WSYGIVMWEVMSYGERPYWDMTNQDVINAIEQDYRLPPPMDCPSALHQLMLDCWQKDRNH 869
           WS+G++MWE+ + G+ PY ++   ++ + ++  YRL  P +CP  L  +M  CW      
Sbjct: 169 WSFGVLMWEMCTLGKLPYAEIDPYEMEHYLKDGYRLAQPFNCPDELFTIMAYCWASMPAE 348

Query: 870 RPKFGQI 876
           RP F Q+
Sbjct: 349 RPSFSQL 369
>07833
          Length = 1504

 Score = 82.8 bits (203), Expect = 6e-16,   Method: Compositional matrix adjust.
 Identities = 63/237 (26%), Positives = 120/237 (50%), Gaps = 13/237 (5%)
 Frame = -3

Query: 660  TEKQRRDFLSEASIMGQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDSFLRQNDGQFT 719
            T++  RDF+ E   +  F+HPNV+ +     +   +++I++FM  GSL + L    G   
Sbjct: 1499 TKRITRDFMEEFPRLRIFNHPNVLPVLACCNQPPNLVLISQFMPFGSLYNTLHGESG--I 1326

Query: 720  VIQLVGMLR---GIAAGMKYLADM-----NYVHRDLAARNILVNSNLVCKVSDFGLSRFL 771
            V+     LR    IA GM++L  M     N++   L +++++++ +L  ++         
Sbjct: 1325 VVDQNQSLRFAMDIARGMEFLHSMEPTIPNFL---LTSKHVMIDEDLTARI--------- 1182

Query: 772  EDDTSDPTYTSALGGKI-PIRWTAPEAIQYRK---FTSASDVWSYGIVMWEVMSYGERPY 827
              + +D  ++    GK+    W APEA+Q R     T A+D+WS+ I+MWE +   E P+
Sbjct: 1181 --NMADYCFSFHEKGKVYSPAWMAPEALQRRPDDINTRAADMWSFAILMWE-LETREVPF 1011

Query: 828  WDMTNQDV-INAIEQDYRLPPPMDCPSALHQLMLDCWQKDRNHRPKFGQIVNTLDKM 883
             ++++ +V +    +  R+  P      + +L+  C  ++   RP+F  I+  L+KM
Sbjct: 1010 AELSSMEVGMKVALEGLRISIPPGISLHMSRLIKICMNEEPGKRPRFDMIIPILEKM 840
>18921
          Length = 697

 Score = 79.0 bits (193), Expect = 8e-15,   Method: Compositional matrix adjust.
 Identities = 57/200 (28%), Positives = 95/200 (47%)
 Frame = +2

Query: 627 IGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVIHLE 686
           +G G +G V     K  G+    +AIK +     +   ++ + E SIM Q D   ++   
Sbjct: 53  LGEGSYGSVFKSLHKETGQ---VLAIKQVP---VDTDLQEIIKEISIMQQCDSKYIVKYY 214

Query: 687 GVVTKSTPVMIITEFMENGSLDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLADMNYVHRD 746
           G   K+T + I+ E+   GS+   +R  +      ++  +L     G+ YL     +HRD
Sbjct: 215 GSYFKNTDLWIVMEYCGAGSVSDIMRLRNKTLVEREIATILYYTLKGLXYLHSRRKIHRD 394

Query: 747 LAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSALGGKIPIRWTAPEAIQYRKFTSA 806
           + A NIL+N+    K++DFG++  L D  +     + +G      W APE IQ   +   
Sbjct: 395 IKAGNILLNNEGHAKLADFGVAGQLTDTMAKR--NTVIGTP---YWMAPEVIQEIGYDCV 559

Query: 807 SDVWSYGIVMWEVMSYGERP 826
           +D+WS GI   E M+ G+ P
Sbjct: 560 ADIWSLGITALE-MAEGKPP 616
>00300
          Length = 2318

 Score = 77.0 bits (188), Expect = 4e-14,   Method: Compositional matrix adjust.
 Identities = 57/210 (27%), Positives = 100/210 (47%), Gaps = 4/210 (1%)
 Frame = -1

Query: 627  IGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTE-KQRRDFLSEASIMGQFDHPNVIHL 685
            IG G+FG+V +      G+    +A+K +K    + +Q R+   E  I     H N++  
Sbjct: 1634 IGEGQFGKVYTAVNMSTGE---LMALKEMKFQPNDLQQLREMCDEIKIFEGIQHENLVKY 1464

Query: 686  EGVVTKSTPVMIITEFMENGSLDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLADMNYVHR 745
             GV      +++  E+ + G+++   +    ++ + +     R I   + +L + + VHR
Sbjct: 1463 YGVEVHKDEMLMFMEYCDTGTIEEAAKMGLPEYLIRRYT---REIVLAVNHLHENSIVHR 1293

Query: 746  DLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSALGGKIPIRWTAPEAIQYRK--- 802
            D+   NI + SN   K+ DFG S  L+  T+ P     L G     + APE         
Sbjct: 1292 DIKGANIFLTSNGHVKLGDFGCSVKLKSHTTMPGEFHNLVGTTA--YMAPEVFTQNDQGG 1119

Query: 803  FTSASDVWSYGIVMWEVMSYGERPYWDMTN 832
            +  A+D+WS G V+ E M+ G+RP+ D+ N
Sbjct: 1118 YGRAADIWSLGCVVIE-MATGKRPWHDLDN 1032
>14126
          Length = 1265

 Score = 68.6 bits (166), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 65/277 (23%), Positives = 130/277 (46%), Gaps = 14/277 (5%)
 Frame = +3

Query: 593 MKIYIDPFTYEDPNEAVREFAKEIDISCVKIEQV--IGAGEFGEVCSGH-LKLPGKREIF 649
           MK  I P   +  +E+  + ++  D +  K E+V  IG G +G V     L+  G+   F
Sbjct: 105 MKTAISPKGRDGQSESAAKMSRRRDSTEQKYEEVAVIGNGAYGTVYKARDLRNQGE---F 275

Query: 650 VAIKTLKSGYTEKQRRDF-LSEASIMGQ---FDHPNVIHL-----EGVVTKSTPVMIITE 700
           VA+K ++   TE+      + E S++ Q   ++HPNV+ L       +  +   + ++ E
Sbjct: 276 VAMKRIRLNNTEEGMPMMAIREISMLKQLEQYEHPNVVRLLDVSHNTITDREIRLNLVFE 455

Query: 701 FMENGSLDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLADMNYVHRDLAARNILVNSNLVC 760
           ++E+       +         ++  ++  +  G+ +L     VHRDL  +N+L++ +   
Sbjct: 456 YIEHDLATYLAKCPSPGLGPDRIKDLMLQLLNGVDFLHSNRIVHRDLKPQNLLISKDGRL 635

Query: 761 KVSDFGLSRFLEDDTSDPTYTSALGGKIPIRW-TAPEAIQYRKFTSASDVWSYGIVMWEV 819
           K++DFGL+R         ++  AL   +   W  +PE +   ++ ++ D+WS G +  E+
Sbjct: 636 KLADFGLARIY-------SFHMALTTVVVTLWYRSPEVLMQAEYGTSVDIWSCGCIFAEL 794

Query: 820 MSYGERPYWDMTNQ-DVINAIEQDYRLPPPMDCPSAL 855
             +  R  +  +++ D +  I +   LPP  D P  +
Sbjct: 795 --FTRRALFKGSSEFDQLKKIFEVIGLPPAGDWPEGV 899
>01756
          Length = 1858

 Score = 68.2 bits (165), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 56/204 (27%), Positives = 91/204 (44%), Gaps = 11/204 (5%)
 Frame = -3

Query: 627  IGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVIHL- 685
            IG G FGEV     K    +++    K L     E      L E  I+   +H NV+ L 
Sbjct: 1718 IGQGTFGEVFKARCK--KTKQVVAMKKVLMDNEKEGFPITALREIKILQLLNHENVVDLI 1545

Query: 686  EGVVTKSTPV-------MIITEFMENGSLDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLA 738
            E   TK+T          ++ EF E+  L   L      F + ++  +++ +  G+ Y+ 
Sbjct: 1544 EICSTKATSANRYKSMFYLVFEFCEH-DLAGLLSNMSVVFNLPEIKEVMKQLMNGLYYIH 1368

Query: 739  DMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPT-YTSALGGKIPIRWTAPEA 797
                +HRD+ A NIL+    V K++DFGL+R    +   P  YT+    ++   W  P  
Sbjct: 1367 RNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTN----RVVTLWYRPPE 1200

Query: 798  IQY--RKFTSASDVWSYGIVMWEV 819
            +    R +++A D W  G +M E+
Sbjct: 1199 LLLGDRNYSTAIDQWGAGCIMAEM 1128
>19301
          Length = 712

 Score = 66.2 bits (160), Expect = 6e-11,   Method: Compositional matrix adjust.
 Identities = 44/110 (40%), Positives = 61/110 (55%), Gaps = 3/110 (2%)
 Frame = +2

Query: 662 KQRRDFLSEASI--MGQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDSFLRQNDGQFT 719
           K+ RD + E  I  + + +HPN+I  +GV T++    II E+   G L   LR  DG+  
Sbjct: 392 KKVRD-IKETDIRNLRKLNHPNIISFKGVCTQAPCYCIIMEYCPYGQLYEVLR--DGKEI 562

Query: 720 VIQLV-GMLRGIAAGMKYLADMNYVHRDLAARNILVNSNLVCKVSDFGLS 768
              LV    + IA+GM YL     +HRDL + N+LV  N V K+SDFG S
Sbjct: 563 PPALVLDWSKQIASGMNYLHSHKIIHRDLKSPNVLVAKNDVVKISDFGTS 712
>27546
          Length = 426

 Score = 65.1 bits (157), Expect = 1e-10,   Method: Composition-based stats.
 Identities = 31/110 (28%), Positives = 56/110 (50%)
 Frame = -1

Query: 664 RRDFLSEASIMGQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDSFLRQNDGQFTVIQL 723
           ++ F  E  I+ + DHPN+I +  ++ +   + I   + E G + S +++  G     Q 
Sbjct: 348 KKFFPRELEILTRLDHPNIIQIHSILQRGPKIFIFMRYAEKGDMLSHIKKT-GPIDEAQT 172

Query: 724 VGMLRGIAAGMKYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLED 773
                 +A  ++YL   +  HRDL   NIL++  L  K++DFG +R+  D
Sbjct: 171 KVWFFQMAKALQYLHSHDIAHRDLKCENILLSKRLNVKIADFGFARYCRD 22
>14420
          Length = 528

 Score = 63.5 bits (153), Expect = 4e-10,   Method: Compositional matrix adjust.
 Identities = 39/170 (22%), Positives = 83/170 (48%), Gaps = 3/170 (1%)
 Frame = +2

Query: 661 EKQRRDFLSEASIMGQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDSFLRQ---NDGQ 717
           + ++   ++E  +M +  +PN+++          + ++ EF+  GSL   + +   ++GQ
Sbjct: 23  QPKKELIINEILVMRENQNPNIVNYLDSYLVGEELWVVMEFLAGGSLTDVVTETCMDEGQ 202

Query: 718 FTVIQLVGMLRGIAAGMKYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSD 777
              +      R     +++L +   +HRD+ + NIL+  +   K++DFG    L  + S 
Sbjct: 203 IAAV-----CRECLQALEFLHENQVIHRDIKSDNILLGMDGSVKLTDFGFCAQLSPEQSK 367

Query: 778 PTYTSALGGKIPIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPY 827
              ++ +G      W APE +  +++    D+WS G++  E++  GE PY
Sbjct: 368 --RSTMVGTP---YWMAPEVVTRKQYGPTVDIWSLGVMCIEMIE-GEPPY 499
>09606
          Length = 1300

 Score = 61.2 bits (147), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 51/219 (23%), Positives = 95/219 (43%), Gaps = 21/219 (9%)
 Frame = -3

Query: 649  FVAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLD 708
            FVAI  ++    + +R +  +   +     HPNV+        S  + ++ E    GSL 
Sbjct: 1034 FVAIHCIE----KCKRPEVTNTVRMTHDISHPNVVQFHEWYETSNHLWLVVELCTGGSLA 867

Query: 709  SFLRQNDGQFTVIQLVGMLRGIAAGMKYLADMNYVHRDLAARNILVNSNLVCKVSDFGLS 768
              L Q D       +      +  G+ Y+  +  +  DL    +L++++ V K +DFGLS
Sbjct: 866  DILAQ-DHHLPETSIRDFGIHLVTGLHYIHSLGILFHDLRPSKVLLDTSGVLKFADFGLS 690

Query: 769  RFLEDDTSDPTYTSALGG-------------KIPIR----WTAPEAIQYRKFTSASDVWS 811
            +   ++  +  +  A  G             ++P      + APE  Q  + +  SD+W+
Sbjct: 689  KVEGENLEELFFKFAEAGDQWNIQSAEEMMKQVPTSGSPTYMAPEVFQGAEPSIMSDLWA 510

Query: 812  YGIVMWEVMSYGERPY----WDMTNQDVINAIEQDYRLP 846
             G V +E+ S G  P+    +D+T   V+N   +++ LP
Sbjct: 509  LGCVFYEMFS-GHPPFLGETYDITKDKVLN---KEFPLP 405
>18484
          Length = 635

 Score = 60.8 bits (146), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 45/173 (26%), Positives = 85/173 (49%), Gaps = 12/173 (6%)
 Frame = +1

Query: 713 QNDGQFTVIQLVGMLRGIAAGMKYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLE 772
           Q +G+F           IA G+ +L D   ++RDL   N++++S    K++DFG+ +  E
Sbjct: 19  QQEGKFKEPVAAFYAAEIAVGLFFLHDQGIIYRDLKLDNVMLDSEGHIKIADFGMCK--E 192

Query: 773 DDTSDPTYTSALGGKIPIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTN 832
             T D T  +  G      + APE + Y+ ++ + D W+YG++++E+++ G+ P+     
Sbjct: 193 GMTGDATTRTFCGTP---DYIAPEIVLYQPYSKSVDWWAYGVLLFEMLA-GQPPFDGEDE 360

Query: 833 QDVINAI-EQDYRLPPPMD------CPSALHQ---LMLDCWQK--DRNHRPKF 873
            ++ ++I + +   P  M       C   L +     L C  K   R+ RP+F
Sbjct: 361 DELFSSITDHNVSYPKAMSREAVSLCKGLLMKNPTKRLGCGSKW*TRHQRPRF 519
>21079
          Length = 878

 Score = 60.5 bits (145), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 42/146 (28%), Positives = 73/146 (50%), Gaps = 3/146 (2%)
 Frame = +1

Query: 679 HPNVIHLEGVVTKSTPVMIITEFMENGSLDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLA 738
           HP ++ L         ++++ EF+  G L   + ++D   T    V  +R I +G+ Y+ 
Sbjct: 1   HPKLLMLWDAFEAPRTMVLVMEFVGAGELFERVIRDDFVLTERDCVHFVRQICSGVGYMH 180

Query: 739 DMNYVHRDLAARNILV---NSNLVCKVSDFGLSRFLEDDTSDPTYTSALGGKIPIRWTAP 795
             + +H DL   N+L    NSN + K+ DFGL+RF +   S       L G  P  + AP
Sbjct: 181 TQSILHLDLKPENVLCVSDNSNQI-KIIDFGLARFYKPGDS----LQVLFGT-P-EFIAP 339

Query: 796 EAIQYRKFTSASDVWSYGIVMWEVMS 821
           E + Y +    +D+WS G++ + ++S
Sbjct: 340 EVVNYDEINFTTDMWSIGVICYILLS 417
>01060
          Length = 1800

 Score = 58.9 bits (141), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 49/202 (24%), Positives = 96/202 (47%), Gaps = 6/202 (2%)
 Frame = +1

Query: 625 QVIGAGEFGEVCSGHLKLPGKREIFVAIKTLK-SGYTEKQRRDFLSEASIMGQFDHPNVI 683
           Q IG G +G V     +  G++   +A+K ++  G  +      + E +++ +  H N++
Sbjct: 91  QKIGEGTYGVVYKCRHRATGRK---LAMKKIRLRGSEDGVPSSAIREIAMLRELRHTNIV 261

Query: 684 HLEGVVTKSTPVMIITEFME---NGSLDSFLRQNDGQFTVIQLV-GMLRGIAAGMKYLAD 739
            LE V+ +   + ++ EF+       +D F    +G     +LV   +  I  G+ +   
Sbjct: 262 CLEDVIMEDERLFLVFEFLSMDLKMYIDKF---PEGVVLDRRLVKSYVFQIVTGIXFCHQ 432

Query: 740 MNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSALGGKIPIRWTAPEAIQ 799
              VHRDL  +N+L+N     K++DFG++R          YT  +   + + + APE + 
Sbjct: 433 RRIVHRDLKPQNLLINHTGAIKIADFGMARTFALPVR--AYTHEV---VTLWYRAPEILM 597

Query: 800 -YRKFTSASDVWSYGIVMWEVM 820
              K+++  DVWS G +  +++
Sbjct: 598 GASKYSTPVDVWSIGTIFADML 663
>29581
          Length = 1278

 Score = 58.5 bits (140), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 42/160 (26%), Positives = 79/160 (49%), Gaps = 4/160 (2%)
 Frame = -2

Query: 671  ASIMGQFDHPNVIHLEGVVTKST--PVMIITEFMENGSLDSFLRQNDGQFTVIQLVGMLR 728
            ++ +    H N++ L+ VV   +   + ++ E+ E   L S L      F+  Q+  ++ 
Sbjct: 1202 STFLLNLRHQNIVQLQEVVVGKSLDSLFLVMEYCEQ-DLASLLDNMPAPFSESQVKCIVL 1026

Query: 729  GIAAGMKYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSALGGKI 788
             +  G++YL +   +HRDL   N+L+      K++DFGL+R    +   P     +  K+
Sbjct: 1025 QLLKGLRYLHEAFIIHRDLKVSNLLMTDKGCVKIADFGLAR----NYGKP--QKPMTPKV 864

Query: 789  PIRW-TAPEAIQYRK-FTSASDVWSYGIVMWEVMSYGERP 826
               W  APE +   K  ++A D+WS G ++ E++  G +P
Sbjct: 863  VTLWYRAPELLFGSKTHSTAIDMWSAGCILGELL--GHKP 750
>15910
          Length = 1361

 Score = 56.6 bits (135), Expect = 5e-08,   Method: Compositional matrix adjust.
 Identities = 34/116 (29%), Positives = 59/116 (50%), Gaps = 3/116 (2%)
 Frame = +2

Query: 716 GQFTVIQLVGMLRGIAAGMKYLADMNYVHRDLAARNIL---VNSNLVCKVSDFGLSRFLE 772
           GQ+T       +  I  G++Y+     VHRDL   N+L   +  +   K++DFGLSR +E
Sbjct: 449 GQYTEKDAARAISDILHGVQYIHANGVVHRDLKPENLLYECMTDDSKLKLADFGLSRIIE 628

Query: 773 DDTSDPTYTSALGGKIPIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYW 828
            +    T     G      + APE ++  K+T + D+WS G++ + ++  G  P++
Sbjct: 629 PEVQMSTVCGTPG------YCAPEVLKGDKYTPSVDMWSVGVIAY-ILLCGYEPFF 775
>13066
          Length = 551

 Score = 56.6 bits (135), Expect = 5e-08,   Method: Compositional matrix adjust.
 Identities = 43/174 (24%), Positives = 74/174 (42%), Gaps = 6/174 (3%)
 Frame = +3

Query: 646 REIFVAIKTLKSGYTEKQRRDFLS-----EASIMGQFDHPNVIHLEGVVTKSTPVMIITE 700
           R I +A K +     EK   DF+      E  ++ + DHP +I +  ++ +     I   
Sbjct: 48  RNIKLACKIIDK---EKAPVDFVEKFFPRELDLLTKLDHPYIIQIHSILQRXPKNFIFMR 218

Query: 701 FMENGSLDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLADMNYVHRDLAARNILVNSNLVC 760
           F E G L +++ Q  G     Q       +   + YL   +  HRDL   NIL++S+   
Sbjct: 219 FAERGDLLTYI-QEVGFVKEKQAKIWFYQMTTALNYLHSYDVAHRDLKCENILLSSHFNV 395

Query: 761 KVSDFGLSRFLEDDTSDPTYTSALGGKIPIRWTAPEAIQYRKFT-SASDVWSYG 813
           K++DFG +     ++ +   +    G     + APE +    +    +D WS G
Sbjct: 396 KLADFGFACACITESGEKYMSRTYCGSAA--YAAPEIVYGAPYAPKVADAWSLG 551
>19094
          Length = 898

 Score = 56.2 bits (134), Expect = 6e-08,   Method: Composition-based stats.
 Identities = 34/115 (29%), Positives = 56/115 (48%)
 Frame = +1

Query: 705 GSLDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLADMNYVHRDLAARNILVNSNLVCKVSD 764
           GS+   +R  +      ++  +L     G+ YL     +HRD+ A NIL+N+    K++D
Sbjct: 10  GSVSDIMRLRNKTLVEREIATILYYTLKGL*YLHSRRKIHRDIKAGNILLNNEGHAKLAD 189

Query: 765 FGLSRFLEDDTSDPTYTSALGGKIPIRWTAPEAIQYRKFTSASDVWSYGIVMWEV 819
           FG++  L D  +     + +G      W APE IQ   +   +D+WS GI   E+
Sbjct: 190 FGVAGQLTDTMA--KRNTVIGTPY---WMAPEVIQEIGYDCVADIWSLGITALEM 339
>04591
          Length = 1117

 Score = 56.2 bits (134), Expect = 6e-08,   Method: Compositional matrix adjust.
 Identities = 44/165 (26%), Positives = 76/165 (46%), Gaps = 11/165 (6%)
 Frame = -2

Query: 668  LSEASIMGQFDHPNVIHLEGVV-TKSTP-------VMIITEFMENGSLDSFLRQNDGQFT 719
            L E  I+ Q +H NV+ L+ +  T++ P         +I E+ +   L   L     +F+
Sbjct: 1077 LREIKILQQLEHENVVQLQEICHTQAGPYNRYKSTFYLIFEYCDY-DLAGLLNNLRVKFS 901

Query: 720  VIQLVGMLRGIAAGMKYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPT 779
            +     ++  +  G+ Y+     +HRD+ A NIL+  + V K++DFGLSR        P 
Sbjct: 900  LADKKNLMSQLLNGLFYIHTKQILHRDIKAANILLTRDGVLKLADFGLSR--------PW 745

Query: 780  YTSA-LGGKIPIRWTAPEAIQY--RKFTSASDVWSYGIVMWEVMS 821
              S  L  ++   W  P  +    R++    D+W  G +M E+ S
Sbjct: 744  VKSKRLTNRVVTLWYRPPELLLGEREYGPEIDMWGVGCIMAEMWS 610
>07836
          Length = 1478

 Score = 56.2 bits (134), Expect = 7e-08,   Method: Compositional matrix adjust.
 Identities = 46/173 (26%), Positives = 82/173 (47%), Gaps = 19/173 (10%)
 Frame = -1

Query: 693  TPVMIITEFMENGSLDSFL--RQNDGQFTVIQLVGMLRGIAAGMKYLADMNY-------- 742
            T + +IT++ ENGSL  +L  R  D      +++ +      G+ +L    +        
Sbjct: 1334 TQLFLITDYHENGSLHDYLLSRVLDSS----EMLALAHSAICGLAHLHIEIFGTRGKPAI 1167

Query: 743  VHRDLAARNILVNSNLVCKVSDFGLS-RFL-EDDTSDPTYTSALGGKIPIRWTAPEAIQ- 799
             HRD+ ++NILV  N  C ++D GL+ R++ E +  D       G K   R+ APE ++ 
Sbjct: 1166 AHRDIKSKNILVKKNGTCCIADLGLAVRYISESNEVDVAPNPRQGTK---RYMAPEVLEM 996

Query: 800  ------YRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIEQDYRLP 846
                  +  F  A D++++G+VMWE+               VI  + ++Y++P
Sbjct: 995  LLNVKNFDAFKQA-DMYAFGLVMWEI-----------ARCCVIGGVAEEYQVP 873
>00715
          Length = 1788

 Score = 54.7 bits (130), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 60/264 (22%), Positives = 104/264 (39%), Gaps = 29/264 (10%)
 Frame = +1

Query: 646 REIFVAIKTLKSGYTEKQRRDFLSEA-SIMGQFDHPNVIHLEGVVTK---STPVMIITEF 701
           R + V I   +S      R+ + +E  +      H NV+ + G  +         +  E+
Sbjct: 1   RTVAVKIYHKRSSNPRALRQSYSNELLAFRCGLRHVNVVSILGATSLHRFEDGAWLAMEY 180

Query: 702 MENGSLDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLADMNYVHRDLAARNILVNSNLVCK 761
           +   +L + L  +         + +   +A G+ YL  +N VH DL   N L+  +L  +
Sbjct: 181 VGPLNLQTILNDHQQDIDSSMRLSLALQMARGLHYLHSINIVHLDLKPANCLLTRDLKLR 360

Query: 762 VSDFGLSRFLEDDTSD-------------------PTYTSALGGKIPIRWTAPEAIQYRK 802
           ++DFG    L     D                     + + L G +  R  APE ++  +
Sbjct: 361 IADFGCCHQLTPTGLDMGEREGGMAGNELELTPVQGAWKNELAGTLAYR--APELLKGLQ 534

Query: 803 FTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVI-NAIEQDYR-LPPPM--DCP--SALH 856
            +  SDV+S GI +W+ M   + PY  +    V+   + +D R  PPP   D P      
Sbjct: 535 PSVRSDVYSLGITLWQ-MCTRQGPYEGVPAHAVVYQVVSKDLRPCPPPSTEDDPFEVMFR 711

Query: 857 QLMLDCWQKDRNHRPKFGQIVNTL 880
            L   CW +    RP    +V+ +
Sbjct: 712 DLYTQCWARRVEDRPTSLDVVHAI 783
>13212
          Length = 1067

 Score = 54.3 bits (129), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 44/183 (24%), Positives = 83/183 (45%), Gaps = 9/183 (4%)
 Frame = -1

Query: 705  GSLDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLADMNYVHRDLAARNILVNSNLVCKVSD 764
            G+LDS +   +   T  Q+  +   +   + +L   + +HRD+ A N+L+  +   K++D
Sbjct: 1028 GALDSIMVDLEKPMTEAQICYVCHEMCMALDFLHRHHVIHRDIKAGNVLLTIDGEVKLAD 849

Query: 765  FGLSRFLEDDTSDPTYTSALGGKIPIRWTAPEAI-----QYRKFTSASDVWSYGIVMWEV 819
            FG+S   ++  +     + +G      W APE +     +   +   +D+WS G+ + E 
Sbjct: 848  FGVS--AKNTQTQQKRDTFIGTPY---WMAPEVVLCETLKDTPYDFKADIWSLGVTLIE- 687

Query: 820  MSYGERPYWDMTNQDVINAIEQDYRLPPPMDCPSALHQLMLD----CWQKDRNHRPKFGQ 875
             +  E P  +M    V+  I +    PP ++ P    +L  D    C  KD N RP   +
Sbjct: 686  FAQIEPPNKEMHPMRVLIKIHKSD--PPTLEKPKKWTKLFKDFIAKCLVKDPNLRPTAAE 513

Query: 876  IVN 878
            ++ 
Sbjct: 512  LLE 504
>12672
          Length = 773

 Score = 53.9 bits (128), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 31/98 (31%), Positives = 56/98 (57%), Gaps = 2/98 (2%)
 Frame = +3

Query: 726 MLRGIAAGMKYLADMNYVHRDLAARNILVNSNLVCKVSDFG--LSRFLEDDTSDPTYTSA 783
           +++G A+G++YL D  +VHRD+   NIL++S    KV DF   +S    +  +    +  
Sbjct: 6   IVKGTASGIQYLNDNGHVHRDIKTANILLDSEYTAKVGDFATVVSAPSGEGKTVQNASVV 185

Query: 784 LGGKIPIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMS 821
           +G      + APEAI +   ++  D +S+G+V+ EV++
Sbjct: 186 IG---TAAYLAPEAIHF-DVSTKLDSYSFGVVLLEVIT 287
>17975
          Length = 449

 Score = 52.8 bits (125), Expect = 7e-07,   Method: Composition-based stats.
 Identities = 38/133 (28%), Positives = 59/133 (44%), Gaps = 7/133 (5%)
 Frame = +3

Query: 646 REIF----VAIKTL-KSGYTEKQRRDFLSEASIMGQFDHPNVIHLEGVVTKSTPVMIITE 700
           R +F    VA+K + K+   E  R     E   M    HPNV+ L  V+   T + +I E
Sbjct: 27  RHVFTGEKVAVKVIDKTKLDEVSRSHLFQEVRCMKLVQHPNVVRLYEVIDTQTKLYLILE 206

Query: 701 FMENGSLDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLADMNYVHRDLAARNILV--NSNL 758
             + G +  ++ ++ G           R I   + Y   ++ VHRDL   N++      L
Sbjct: 207 LGDGGDMYDYIMRHSGGLEEKLAKRYFRQIVEAISYCHKLHVVHRDLKPENVVFFEKPGL 386

Query: 759 VCKVSDFGLSRFL 771
           V K++DFG S  L
Sbjct: 387 V-KLTDFGFSTCL 422
>31885
          Length = 529

 Score = 52.8 bits (125), Expect = 8e-07,   Method: Compositional matrix adjust.
 Identities = 42/162 (25%), Positives = 74/162 (45%), Gaps = 5/162 (3%)
 Frame = -2

Query: 671 ASIMGQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDSFLRQNDGQFTVIQLVGMLRGI 730
             ++ + DHP +++L         + ++ +    G L  +  Q +  F    +   L  +
Sbjct: 519 VDMLTRLDHPFLVNLWYAFQDEEDLFMVVDLFLGGDL-RYHMQQEVSFREDCVKFYLCQL 343

Query: 731 AAGMKYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSALGGKIPI 790
           A  + YL     VHRD+   NIL++    C V+DF ++  LEDD       ++  G  P 
Sbjct: 342 ALVLDYLRSQKIVHRDIKPDNILLDEQGHCHVTDFNIATQLEDD----ELATSTSGTRP- 178

Query: 791 RWTAPE----AIQYRK-FTSASDVWSYGIVMWEVMSYGERPY 827
            + APE    AI  R+ +    D WS G+ ++E++    RP+
Sbjct: 177 -YMAPEVYGVAINERRGYGFPVDWWSLGVSLFELLK-KRRPF 58
>30755
          Length = 1137

 Score = 51.6 bits (122), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 34/118 (28%), Positives = 59/118 (50%), Gaps = 1/118 (0%)
 Frame = +2

Query: 730 IAAGMKYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSALGGKIP 789
           I + + YL     ++RDL   N+L++ +   KV+DFGL +  ED T   T  +  G    
Sbjct: 59  IISALGYLHSQGIIYRDLKLENLLLDKDGHIKVADFGLCK--EDITYGRTTKTFCGTP-- 226

Query: 790 IRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAI-EQDYRLP 846
             + APE +    +  A D W  G+VM+E++  G  P+++  +  +   I  +D + P
Sbjct: 227 -EYLAPEVLDDNDYGRAVDWWGTGVVMYEMIC-GRLPFYNRDHDVLFTLILVEDVKFP 394
>01707
          Length = 757

 Score = 50.8 bits (120), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 47/201 (23%), Positives = 86/201 (42%), Gaps = 6/201 (2%)
 Frame = +1

Query: 627 IGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQ-RRDFLSEASIMGQFDHPNVIHL 685
           IG G +G V     K   +    VAIK       +   ++  + E  ++ Q  HPN++ L
Sbjct: 88  IGEGSYGVVFKCRNKETSQ---LVAIKKFVESEDDPLIKKIAMREIRMLKQLKHPNLVRL 258

Query: 686 EGVVTKSTPVMIITEFMENGSLDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLADMNYVHR 745
             V  +   + ++ +++++  L+   R   G      +  ++      + +    N +HR
Sbjct: 259 IEVFRRKKRLHLVFDYVDHTLLNELDRYPRG-LPEPMVKRIIYQTLLAVNFCHQYNTIHR 435

Query: 746 DLAARNILVNSNLVCKVSDFGLSRFLE---DDTSDPTYTSALGGKIPIRW-TAPE-AIQY 800
           D+   NIL+      K+ DFG +R L    D+ +D   T         RW  APE  +  
Sbjct: 436 DVKPENILITRQGQVKLCDFGFARILTGPGDEYTDYVAT---------RWYRAPELLVGD 588

Query: 801 RKFTSASDVWSYGIVMWEVMS 821
            ++    DVW+ G V  E+++
Sbjct: 589 TQYGPPVDVWAIGCVFAELLT 651
>19544
          Length = 1421

 Score = 47.8 bits (112), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 53/199 (26%), Positives = 78/199 (39%), Gaps = 6/199 (3%)
 Frame = +2

Query: 325 PSAPQAVISSVNETSLMLEWT--PPRDSGGREDLVYNIICKSCGSGRGACTRCGDNVQYA 382
           PS  QAV  S   +S+ + W   PP    G       +  K   S     TR        
Sbjct: 116 PSNVQAVNKSA--SSIQVTWVAPPPETQNGGLSGYKVLYYKQSSSAEEELTRI------- 268

Query: 383 PRQLGLTEPRIYISDLLAHTQYTFEIQAVNGVTDQSPFSPQFASVNITTNQAAPSAVSIM 442
                  E  I +  L   T Y   +Q  N   +     P+ A V+  T++  PSA   +
Sbjct: 269 -----TAETHILLESLETFTVYFIAVQPYNLAGE----GPRSALVSAQTSEGVPSAPQSI 421

Query: 443 HQVSRTVDSITLSWSQPDQPNGVILDYELQYYEKELSEYNATA----IKSPTNTVTVQGL 498
              + T+  + + +  P  PNG IL YE+QY+ K+ S Y   A    +++    V V  L
Sbjct: 422 RFTNITMRQLMVHFDPPTTPNGHILLYEMQYFPKDESRYGFLAPKRILRANETRVVVTEL 601

Query: 499 KAGAIYVFQVRARTVAGYG 517
           +    Y F + A T  G G
Sbjct: 602 EKRVWYKFIISANTSIGKG 658
>01966
          Length = 1735

 Score = 47.8 bits (112), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 28/106 (26%), Positives = 54/106 (50%), Gaps = 4/106 (3%)
 Frame = -1

Query: 668  LSEASIMGQFDHPNVIHLEGVVTKSTPVMIITEFME---NGSLDSFLRQNDGQFTVIQLV 724
            + E +++ +  H N++ LE V+ +   + ++ EF+       +D F    +G     +LV
Sbjct: 1570 IREIAMLRELRHTNIVCLEDVIMEDERLFLVFEFLSMDLKMYIDKF---PEGVVLDRRLV 1400

Query: 725  -GMLRGIAAGMKYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSR 769
               +  I  G+ +      VHRDL  +N+L+N     K++DFG++R
Sbjct: 1399 KSYVFQIVTGINFCHQRRIVHRDLKPQNLLINHTGAIKIADFGMAR 1262
>26711
          Length = 405

 Score = 46.6 bits (109), Expect = 5e-05,   Method: Composition-based stats.
 Identities = 30/105 (28%), Positives = 58/105 (55%), Gaps = 2/105 (1%)
 Frame = -2

Query: 725 GMLRGIAAGMKYLADMNYVHRDLAARNILVNSNLVCKVS--DFGLSRFLEDDTSDPTYTS 782
           G+++ +   ++++     VH DL   N+L++ + +  V   DFGL+R L      P   +
Sbjct: 404 GVVKQVLDILQHVHAQGVVHMDLKPSNLLLSGDKLDSVQLIDFGLARKLY-----PPQET 240

Query: 783 ALGGKIPIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPY 827
            L    P  +T+PEA+  +  ++ASDVW  G++ + ++S G+ P+
Sbjct: 239 FLNHGTP-GFTSPEALDVKPISTASDVWGVGVLAYILLS-GQSPF 111
>17806
          Length = 433

 Score = 46.6 bits (109), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 27/93 (29%), Positives = 46/93 (49%), Gaps = 2/93 (2%)
 Frame = +1

Query: 627 IGAGEFGEVCSGHLK--LPGKREIFVAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVIH 684
           +G G FG+V     +    G     V +K LK   T+ ++  F  E +   + DHPN++ 
Sbjct: 73  LGTGWFGKVIESDAERITTGVSRSKVVVKMLKDDATKDEQLLFFEEVAPFRELDHPNIVR 252

Query: 685 LEGVVTKSTPVMIITEFMENGSLDSFLRQNDGQ 717
           L G  T+  P++++ E    G+L  +LR +  Q
Sbjct: 253 LLGQCTEMNPMLMLMECAALGNLKQYLRNHRHQ 351
>04138
          Length = 800

 Score = 46.2 bits (108), Expect = 7e-05,   Method: Compositional matrix adjust.
 Identities = 27/91 (29%), Positives = 46/91 (50%), Gaps = 3/91 (3%)
 Frame = +1

Query: 734 MKYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPT-YTSALGGKIPIRW 792
           + Y+     +HRD+ A NIL+    V K++DFGL+R    +   P  YT+    ++   W
Sbjct: 52  LYYIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTN----RVVTLW 219

Query: 793 TAPEAIQY--RKFTSASDVWSYGIVMWEVMS 821
             P  +    R +++A D W  G +M E+ +
Sbjct: 220 YRPPELLLGDRNYSTAIDQWGAGCIMAEMWT 312
>03240
          Length = 1683

 Score = 45.4 bits (106), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 37/151 (24%), Positives = 67/151 (44%), Gaps = 8/151 (5%)
 Frame = -3

Query: 625  QVIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRR--DFLSEASIMGQFDHPNV 682
            + +G G FGEV        G   +  A+KTL+     K+ +     +E  I+ + D+  V
Sbjct: 1273 KTLGVGAFGEVSLCRKNDTG---MLYAMKTLRKSDVLKRNQVAHVKAERDILAEADNEWV 1103

Query: 683  IHLEGVVTKSTPVMIITEFMENGSLDSFLRQND------GQFTVIQLVGMLRGIAAGMKY 736
            + L         +  + +++  G L   L + +       +F V +LV  +  +      
Sbjct: 1102 VKLYYSFQDHNYLYFVMDYVPGGDLMGLLIRMEILDEPLARFYVAELVQAIESVHR---- 935

Query: 737  LADMNYVHRDLAARNILVNSNLVCKVSDFGL 767
               M ++HRD+   NIL++ N   K++DFGL
Sbjct: 934  ---MGFIHRDIKPDNILIDRNGHIKLTDFGL 851
>25550
          Length = 941

 Score = 44.7 bits (104), Expect(2) = 1e-04,   Method: Composition-based stats.
 Identities = 24/68 (35%), Positives = 37/68 (54%)
 Frame = +3

Query: 816 MWEVMSYGERPYWDMTNQDVINAIEQDYRLPPPMDCPSALHQLMLDCWQKDRNHRPKFGQ 875
           +W+V      P  D+T  +V + +E+ YR+  P   P+ ++ LML CWQ D   RP F +
Sbjct: 27  IWDV----XYPGVDLT--EVYHLLERGYRMERPQGTPADVYILMLKCWQWDPKERPTFKE 188

Query: 876 IVNTLDKM 883
           I   L+ M
Sbjct: 189 IHYLLENM 212

 Score = 20.0 bits (40), Expect(2) = 1e-04,   Method: Compositional matrix adjust.
 Identities = 5/11 (45%), Positives = 10/11 (90%)
 Frame = +1

Query: 813 GIVMWEVMSYG 823
           G+++WE+ +YG
Sbjct: 1   GVLLWELATYG 33
>19761
          Length = 473

 Score = 44.3 bits (103), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 29/106 (27%), Positives = 53/106 (50%)
 Frame = -3

Query: 743 VHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSALGGKIPIRWTAPEAIQYRK 802
           +HRDL  +NI V      ++ D GL+R L   T    + ++  G I   + +PE +  + 
Sbjct: 351 LHRDLKPQNIYVTEKGDVRLGDLGLARKL---TGPADFATSQVGTI--MYLSPEILSQQP 187

Query: 803 FTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIEQDYRLPPP 848
           + S SD+WS G V +++   G++   +M    ++  +    +LP P
Sbjct: 186 YNSKSDIWSLGCVFYDIT--GKKGSDEMGVMFLLVQVMGGRKLPLP 55
>02638
          Length = 1490

 Score = 44.3 bits (103), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 28/89 (31%), Positives = 47/89 (52%), Gaps = 7/89 (7%)
 Frame = +1

Query: 790 IRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIEQDYRL---- 845
           I + APE ++   +  A DVWS G VM E+ +   RP W+  + D+ N +   +++    
Sbjct: 28  IAFMAPEVLRGESYGRACDVWSVGCVMIEMCTC--RPPWN--SHDISNHLALIFKIASSV 195

Query: 846 -PPPM--DCPSALHQLMLDCWQKDRNHRP 871
            PPP+  +    +  LML C ++D + RP
Sbjct: 196 DPPPIPENMSPPVRDLMLRCLEQDSDFRP 282
>01392
          Length = 1806

 Score = 43.1 bits (100), Expect = 6e-04,   Method: Compositional matrix adjust.
 Identities = 31/120 (25%), Positives = 54/120 (45%), Gaps = 11/120 (9%)
 Frame = -1

Query: 726  MLRGIAAGMKYLADMNYVHRDLAARNIL---VNSNLVCKVSDFGLSRFLE---DDTSDPT 779
            ++R IA  + +L      HRDL   NIL   ++  +  K+ DF L+  +    D T  P 
Sbjct: 1776 VVRHIARALDFLHSKGIAHRDLKPENILCEHLDDVVPVKICDFDLASGISCDGDGTKTPE 1597

Query: 780  YTSALGGKIPIRWTAPEAIQY-----RKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQD 834
              + +G      + APE +         +    D+WS GI+++ +M  G  P++    +D
Sbjct: 1596 LLTPVGSA---EYMAPEVVDAWVGDSFSYDKRCDLWSLGIILY-IMLCGYPPFYGQCGED 1429
>34970
          Length = 505

 Score = 42.7 bits (99), Expect = 8e-04,   Method: Compositional matrix adjust.
 Identities = 16/51 (31%), Positives = 32/51 (62%)
 Frame = -1

Query: 925 IKMGQYKESFANAGFTSFDVVSQMMMEDILRVGVTLAGHQKKILNSIQVMR 975
           + +G Y ++ A+ G+ + D V+ +  ED+  +G+   GHQKKI+ ++  M+
Sbjct: 496 LGLGMYLDTLASQGYDNIDYVTDITWEDLEEIGIKKLGHQKKIMLAVDRMK 344
>11185
          Length = 473

 Score = 42.0 bits (97), Expect = 0.001,   Method: Composition-based stats.
 Identities = 26/109 (23%), Positives = 51/109 (46%), Gaps = 17/109 (15%)
 Frame = +1

Query: 730 IAAGMKYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSALGG--- 786
           +  G+ Y+  +  +  DL    +L++++ V K +DFGLS+   ++  +  +  A  G   
Sbjct: 28  LVTGLHYIHSLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEAGDQW 207

Query: 787 ----------KIPIR----WTAPEAIQYRKFTSASDVWSYGIVMWEVMS 821
                     ++P      + APE  Q  + +  SD+W+ G V +E+ S
Sbjct: 208 NIQSAEEMMKQVPTSGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFS 354
>17679
          Length = 509

 Score = 40.0 bits (92), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 24/88 (27%), Positives = 40/88 (45%), Gaps = 4/88 (4%)
 Frame = +3

Query: 451 SITLSWSQPDQPNGVILDYELQYYEKELSE----YNATAIKSPTNTVTVQGLKAGAIYVF 506
           +I +SWS+P+ PNG+I  Y + +Y ++  E    +    +K+     T+ GL     Y  
Sbjct: 174 TIVVSWSEPEIPNGIIQGYRV-FYTRKPEEPVFFWEQQEVKNDNRLTTISGLDPNQTYTI 350

Query: 507 QVRARTVAGYGRYSGKMYFQTMTEAEYQ 534
            + A +  G G  S  +   T     YQ
Sbjct: 351 SILAYSSIGPGPMSHPIQVLTTQGVPYQ 434
>27287
          Length = 514

 Score = 39.3 bits (90), Expect = 0.007,   Method: Composition-based stats.
 Identities = 22/50 (44%), Positives = 29/50 (58%)
 Frame = -2

Query: 847 PPMDCPSALHQLMLDCWQKDRNHRPKFGQIVNTLDKMIRNPNSLKAMAPL 896
           PP    S +  +M  CWQ+D N RP F ++V  LDKM+   +SLK  A L
Sbjct: 504 PPY-ASSEMFGIMHSCWQEDPNDRPSFSRLVQELDKML--TSSLKDEAYL 364
>12786
          Length = 460

 Score = 38.5 bits (88), Expect = 0.012,   Method: Compositional matrix adjust.
 Identities = 38/128 (29%), Positives = 56/128 (43%), Gaps = 21/128 (16%)
 Frame = -3

Query: 726 MLRGIAAGMKYLADMNYVHRDLAARN-ILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSAL 784
           MLR + A    L +   +H DL   N +LV  NL  K+ DFG++  L+ D +     S +
Sbjct: 383 MLRAVKA----LHNEGVIHSDLKPANFMLVAGNL--KLIDFGIANTLQQDKTSVLKDSRV 222

Query: 785 GGKIPIRWTAPEAIQ---------------YR-----KFTSASDVWSYGIVMWEVMSYGE 824
           G      + +PEAI                +R     K    SDVWS G +++  M YG 
Sbjct: 221 GTP---SYMSPEAIMAACDDSADDSMEEDGHRTKPKYKVGVRSDVWSLGCILYN-MVYGR 54

Query: 825 RPYWDMTN 832
            P+  + N
Sbjct: 53  TPFQHIKN 30
>32264
          Length = 287

 Score = 38.5 bits (88), Expect = 0.013,   Method: Composition-based stats.
 Identities = 16/47 (34%), Positives = 26/47 (55%)
 Frame = +1

Query: 839 IEQDYRLPPPMDCPSALHQLMLDCWQKDRNHRPKFGQIVNTLDKMIR 885
           IE  YRL      P ++++LML CW+     RP F ++  +L  ++R
Sbjct: 1   IEDGYRLQQNPQTPDSVYKLMLRCWEYVPEKRPHFKELYTSLKDIVR 141
>16708
          Length = 1397

 Score = 37.4 bits (85), Expect = 0.027,   Method: Compositional matrix adjust.
 Identities = 47/215 (21%), Positives = 87/215 (40%), Gaps = 16/215 (7%)
 Frame = -1

Query: 621  VKIEQVIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEASIMGQFDHP 680
            V I QV+G G FG+V    L    ++    A+KT  S        +  +   I G F   
Sbjct: 1397 VAILQVLGKGVFGKVYEARLLSTHEK---AALKT--SILCHHSLDEVEALGRIEGGF--- 1242

Query: 681  NVIHLEGVVTKSTP---VMIITEFMENGSLDSFLRQNDGQFTVIQ-----LVGMLRG-IA 731
             +  + G      P   + I+  F E G L +       +   I+     +V  + G   
Sbjct: 1241 YLAQMFGAWVTCLPFPKMNILLHFYEMGPLCNVYAHYKNKEMPIRWSNPAMVCCIAGQXV 1062

Query: 732  AGMKYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFL-------EDDTSDPTYTSAL 784
              ++++ ++  VH D+ A N+LV+++  CK++D+G+++         E  +S  T     
Sbjct: 1061 CALEHIHELGVVHMDVKADNVLVDAHGNCKLTDYGIAQLYKVYPAPTETHSSGCTNKRTF 882

Query: 785  GGKIPIRWTAPEAIQYRKFTSASDVWSYGIVMWEV 819
              + P   T  E          +D +  G ++W +
Sbjct: 881  YTRPPATMTPSERFSEEGDGIGTDYFRLGQMLWTL 777
>26560
          Length = 398

 Score = 37.4 bits (85), Expect = 0.034,   Method: Composition-based stats.
 Identities = 25/99 (25%), Positives = 55/99 (55%), Gaps = 1/99 (1%)
 Frame = -1

Query: 730 IAAGMKYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSALGGKIP 789
           +  G++++     V+RDL   NIL++ N   ++SD GL+     D S     +++G    
Sbjct: 329 VMLGLEHMHSRFVVYRDLKPANILLDENGHVRISDLGLAC----DFSKKRPHASVGTH-- 168

Query: 790 IRWTAPEAI-QYRKFTSASDVWSYGIVMWEVMSYGERPY 827
             + APE + + + + S++D +S+G ++++++  G  P+
Sbjct: 167 -GYMAPEVLMKGQSYDSSADWFSFGCMLYKLLK-GHSPF 57
>27405
          Length = 532

 Score = 36.6 bits (83), Expect = 0.056,   Method: Compositional matrix adjust.
 Identities = 22/72 (30%), Positives = 37/72 (51%)
 Frame = -3

Query: 697 IITEFMENGSLDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLADMNYVHRDLAARNILVNS 756
            I + M  G L   L Q+ G FT  ++      +  G++++     V+RDL   NIL++ 
Sbjct: 323 FILDLMNGGDLHYHLSQH-GVFTEKEVRFYAAEVMLGLEHMHSRFVVYRDLKPANILLDE 147

Query: 757 NLVCKVSDFGLS 768
           N   ++SD GL+
Sbjct: 146 NGHVRISDLGLA 111
>07218
          Length = 1715

 Score = 36.2 bits (82), Expect = 0.063,   Method: Composition-based stats.
 Identities = 19/59 (32%), Positives = 35/59 (59%), Gaps = 3/59 (5%)
 Frame = +1

Query: 917 TVDE---WLEAIKMGQYKESFANAGFTSFDVVSQMMMEDILRVGVTLAGHQKKILNSIQ 972
           T DE   WLE++ +G+Y+ +F +      +++S +   D+  +GVT  GH K+I  +I+
Sbjct: 202 TTDEVGAWLESLSLGEYRANFISHEIRGAELLS-LERRDLKDLGVTKVGHLKRIQQAIK 375
>38046
          Length = 446

 Score = 34.3 bits (77), Expect = 0.24,   Method: Composition-based stats.
 Identities = 14/28 (50%), Positives = 18/28 (64%)
 Frame = -1

Query: 730 IAAGMKYLADMNYVHRDLAARNILVNSN 757
           IA  M Y+   N++HR+L  RNILV  N
Sbjct: 98  IADAMAYMEKENFIHRNLGDRNILVGPN 15
>15741
          Length = 402

 Score = 33.5 bits (75), Expect = 0.38,   Method: Composition-based stats.
 Identities = 16/44 (36%), Positives = 22/44 (50%)
 Frame = -3

Query: 710 FLRQNDGQFTVIQLVGMLRGIAAGMKYLADMNYVHRDLAARNIL 753
           FL       T          +A GM ++A+   VHRD+AARN+L
Sbjct: 133 FLTSTANDLTARDFFSFALHVARGMAHVANNKIVHRDVAARNVL 2
>31489
          Length = 329

 Score = 32.7 bits (73), Expect = 0.73,   Method: Composition-based stats.
 Identities = 24/95 (25%), Positives = 42/95 (44%), Gaps = 6/95 (6%)
 Frame = +3

Query: 673 IMGQFDHPNVIHLEGVVTKSTP------VMIITEFMENGSLDSFLRQNDGQFTVIQLVGM 726
           I+  F H N+I +  ++           + ++ + ME+  L   +  +D   T   +   
Sbjct: 9   ILKHFKHDNIISIREILKPKDSYHDFKDIHVVFDLMES-DLHRII-YSDQPLTEEHIRYF 182

Query: 727 LRGIAAGMKYLADMNYVHRDLAARNILVNSNLVCK 761
           L  I  G+KY+   N VHRDL   N+L    + C+
Sbjct: 183 LYQILRGLKYIHSANVVHRDLKPSNLLSMKIVXCE 287
>28638
          Length = 1458

 Score = 32.7 bits (73), Expect = 0.76,   Method: Compositional matrix adjust.
 Identities = 30/106 (28%), Positives = 46/106 (43%), Gaps = 9/106 (8%)
 Frame = -1

Query: 730 IAAGMKYLA--DMNYVHRDLAARNILVNS--NLVCKVSDFGLSRFLEDDTSDPTYTSALG 785
           +   + +LA  +MN +H DL   NIL+ +      K+ DFG S               LG
Sbjct: 810 LCTALLFLATPEMNIIHCDLKPENILLCNPKRSAIKIVDFGSS-------------CQLG 670

Query: 786 GKI-----PIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERP 826
            +I        + +PE +    +  A D+WS G ++ E M  GE P
Sbjct: 669 QRIYQYIQSRFYRSPEVLLGVPYDLAIDMWSLGCILVE-MHTGEPP 535
>26039
          Length = 441

 Score = 32.0 bits (71), Expect = 1.2,   Method: Composition-based stats.
 Identities = 20/60 (33%), Positives = 27/60 (45%), Gaps = 2/60 (3%)
 Frame = -1

Query: 252 GRCMCKAGFEAVENGTVCRGCPSGTFKANQGDEACTH-CPINSRTTSEGATN-CVCRNGY 309
           GRC+CK G+  +     CR    GTF A      C H C  +     +  T  C+C+ GY
Sbjct: 375 GRCICKPGWTGMRCSEHCR---PGTFGAE-----CKHNCSCSQHGECDPVTGACICQRGY 220
>30103
          Length = 341

 Score = 31.6 bits (70), Expect = 1.5,   Method: Composition-based stats.
 Identities = 20/72 (27%), Positives = 34/72 (47%), Gaps = 4/72 (5%)
 Frame = +1

Query: 452 ITLSWSQP--DQPNGVILDYELQYYEKELSEYNATAIKSPTNT--VTVQGLKAGAIYVFQ 507
           + L W  P   Q NGV+  Y++QY  K     +  ++ +P+      +  + +G  Y  +
Sbjct: 34  VLLKWRPPAARQKNGVLQSYKVQYRRKGSRRGDVCSVITPSQDHHFFLTDVTSGQTYKVR 213

Query: 508 VRARTVAGYGRY 519
           V A TV G G +
Sbjct: 214 VAAMTVNGTGPF 249
>21210
          Length = 518

 Score = 31.6 bits (70), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 26/95 (27%), Positives = 44/95 (46%), Gaps = 9/95 (9%)
 Frame = +3

Query: 792 WTAPEAIQYRK----FTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIEQDYR-LP 846
           + APE I  R     +   SDVWS GI + E+ + G  PY    +  + + ++Q  R + 
Sbjct: 18  YMAPERIDPRASSHGYDVRSDVWSLGITLMELAT-GRFPYRKWVS--IFDQLQQVVRGVA 188

Query: 847 PPMDCPSALHQLMLD----CWQKDRNHRPKFGQIV 877
           P +    A     ++    C  KD   RPK+ +++
Sbjct: 189 PCLPHDGAFSHDFVNFVNKCLTKDEKQRPKYNKLL 293
>33147
          Length = 925

 Score = 31.6 bits (70), Expect = 1.8,   Method: Composition-based stats.
 Identities = 14/44 (31%), Positives = 21/44 (47%)
 Frame = -3

Query: 54  NTIRTYQVCNVFESSQNNWLRTKFIRRRGAHRIHVEMKFSVRDC 97
           +TI   +VC V +  Q +W     + R   H +HV   FS+  C
Sbjct: 563 STIIVSEVCVVLQKMQTSWRTVTRVTRYTCHALHVSRPFSLYMC 432
>07933
          Length = 728

 Score = 31.6 bits (70), Expect = 1.8,   Method: Compositional matrix adjust.
 Identities = 11/38 (28%), Positives = 21/38 (55%)
 Frame = +3

Query: 848 PMDCPSALHQLMLDCWQKDRNHRPKFGQIVNTLDKMIR 885
           P  CP+ L+ +M+ CW  + + RP F ++   +  M+ 
Sbjct: 3   PNYCPNLLYNIMMQCWSAEPSARPTFHKLEQDIVAMVE 116
>37602
          Length = 804

 Score = 31.2 bits (69), Expect = 2.0,   Method: Composition-based stats.
 Identities = 20/69 (28%), Positives = 31/69 (44%)
 Frame = -1

Query: 697 IITEFMENGSLDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLADMNYVHRDLAARNILVNS 756
           I  E+   GS+   +    G  T  Q+  + R    G+ YL     +HRD+   NIL+  
Sbjct: 288 IAMEYCGGGSMQD-IYHVTGPLTEPQIAFVCRETLKGLHYLHRRGKMHRDIKGANILLTE 112

Query: 757 NLVCKVSDF 765
               K++DF
Sbjct: 111 EGDVKLADF 85
>09206
          Length = 873

 Score = 30.4 bits (67), Expect = 3.5,   Method: Composition-based stats.
 Identities = 11/31 (35%), Positives = 17/31 (54%), Gaps = 3/31 (9%)
 Frame = +3

Query: 358 YNIICKSCGSGRGACTRCG---DNVQYAPRQ 385
           Y  +C+ C + +G C +C    D  QYAP +
Sbjct: 375 YYTVCQPCATSKGVCAKCAQKKDVSQYAPDE 467
>21433
          Length = 590

 Score = 30.0 bits (66), Expect = 4.5,   Method: Composition-based stats.
 Identities = 21/91 (23%), Positives = 43/91 (47%)
 Frame = +2

Query: 730 IAAGMKYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSALGGKIP 789
           +++ ++Y      +HRD+   N+L+      K++DFG S  +   +S  T        +P
Sbjct: 194 LSSALEYCHYRKVIHRDIKPENLLLGLKGDLKIADFGWS--VHAPSSRRTTMCGTLDYLP 367

Query: 790 IRWTAPEAIQYRKFTSASDVWSYGIVMWEVM 820
                PE ++ +      D+WS G++ +E +
Sbjct: 368 -----PEMVEGKTHDENVDLWSLGVLCYEFL 445
>07945
          Length = 2023

 Score = 30.0 bits (66), Expect = 5.1,   Method: Compositional matrix adjust.
 Identities = 27/100 (27%), Positives = 36/100 (36%), Gaps = 3/100 (3%)
 Frame = -3

Query: 316  PLDMPCTTIPSAPQAVISSVNETSLMLEWTPPRDSGGREDLVYNIICKSCGSGRG---AC 372
            P   PC   PS P  V + +   SL L W PPR +       Y +        +G     
Sbjct: 1718 PRGKPCP--PSQP--VATDITHNSLTLSWQPPRRNSSDTIYAYTVEKTXPSDXKGWTIVT 1551

Query: 373  TRCGDNVQYAPRQLGLTEPRIYISDLLAHTQYTFEIQAVN 412
            T C  N QY             +  L   +QY F ++A N
Sbjct: 1550 TSCQGN-QYQ------------VKKLSPSSQYVFRVRAEN 1470
>11667
          Length = 1227

 Score = 29.6 bits (65), Expect = 7.0,   Method: Compositional matrix adjust.
 Identities = 32/132 (24%), Positives = 56/132 (42%), Gaps = 8/132 (6%)
 Frame = +3

Query: 252 GRCMCKAGFEAVENGTVCRGCPSGTFKANQGD--EACTHCPINSR--TTSEGATNCV-CR 306
           G+C C AG+E    G +C  C +G +++ + D    C  C I+ +   T +G   C  C+
Sbjct: 312 GKCKCTAGYE----GKLCDSCKAGYYQSEKNDTHTVCKVCHISCKNSCTGDGPKLCSECK 479

Query: 307 NGY-YRADLDPLDM-PCTTIPSAPQAVISSVNETSLMLEWTPPRDSGGREDLVYNIICKS 364
           +G+ +  D+   D+  C T P       ++   + + +                N+ C  
Sbjct: 480 DGWTHNTDIGCQDINECDTSPCKDTEYCTNTQGSYMCMSC--------------NVACDG 617

Query: 365 C-GSGRGACTRC 375
           C GSG   C +C
Sbjct: 618 CTGSGPDHCVKC 653
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|116734870|ref|NP_032543.2| leukotriene A4 hydrolase
[Mus musculus]
         (611 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

22301                                                                 243   1e-64
16587                                                                  95   4e-26
31163                                                                  83   3e-16
20340                                                                  71   2e-12
29830                                                                  40   0.002
26751                                                                  32   1.00 
12737                                                                  29   6.3  
00846                                                                  28   7.4  
>22301
          Length = 980

 Score =  243 bits (620), Expect = 1e-64,   Method: Compositional matrix adjust.
 Identities = 120/272 (44%), Positives = 170/272 (62%), Gaps = 6/272 (2%)
 Frame = +1

Query: 346 GWGELQNTIKTF---GESHPFTXXXXXXXXXXXXXAYSSIPYEKGFALLFYLEQLLGGPE 402
           GW ELQ  +      GE+  +T             A+S +PYEKGFALLFYLE LLGGP 
Sbjct: 4   GWHELQEAVSRMMKEGEA-AYTKLIPDLRGVDPDDAFSIVPYEKGFALLFYLENLLGGPA 180

Query: 403 VFLGFLKAYVKKFSYQSVTTDDWKSFLYSHFKDKVDL--LNQVDWNTWLYAPGLPPVKPN 460
           V+  F+KAY+  F  QS+T+  WK FL+S F D+ D   LN VDW+ W +  G+P V+P 
Sbjct: 181 VYEPFMKAYINXFKNQSITSYQWKDFLFSXFHDQKDQDKLNAVDWDAWFFVEGMPDVQPQ 360

Query: 461 YDVTLTNACIALSQRWVTAKEEDLSSFSIADLKDLSSHQLNEFLAQVLQ-KAPLPLGHIK 519
           +D +L   C  LS RW+ A + DL+SF+ ADL   SS Q  EF+A +LQ  + + L  ++
Sbjct: 361 FDTSLARPCQELSDRWLDASDADLTSFTAADLDGFSSLQTREFIALLLQSDSVVSLDKLQ 540

Query: 520 RMQEVYNFNAINNSEIRFRWLRLCIQSKWEEAIPLALKMATEQGRMKFTRPLFKDLAAFD 579
           +M  +Y  + + NSEIRFRWLRL I+S+W   +  AL+  TEQGRMKF RP+++DL A++
Sbjct: 541 KMDGLYKLSDVKNSEIRFRWLRLGIKSRWPSVVQRALQFVTEQGRMKFVRPIYRDLYAWE 720

Query: 580 KSHDQAVHTYQEHKASMHPVTAMLVGRDLKVD 611
           +S  +A+  +++H+  MH  T   V +DL +D
Sbjct: 721 ESRKEAITNFEQHREEMHNTTVKEVAKDLHLD 816
>16587
          Length = 310

 Score = 95.1 bits (235), Expect(2) = 4e-26,   Method: Compositional matrix adjust.
 Identities = 47/75 (62%), Positives = 55/75 (73%)
 Frame = +3

Query: 184 DPSRKIYRFNQRVPIPCYLIALVVGALESRQIGPRTLVWSEKEQVEKSANEFSETESMLK 243
           D S +++ F Q VPIP YL+A+V G +ESR I  R  VWSEKE V+ +A EFSETE MLK
Sbjct: 21  DGSSRVHTFQQTVPIPSYLLAIVGGDIESRTISNRCKVWSEKELVDAAAFEFSETELMLK 200

Query: 244 IAEDLGGPYVWGQYD 258
            AEDL G YVWGQYD
Sbjct: 201 TAEDLLGDYVWGQYD 245

 Score = 41.6 bits (96), Expect(2) = 4e-26,   Method: Composition-based stats.
 Identities = 16/17 (94%), Positives = 16/17 (94%)
 Frame = +1

Query: 264 PSFPYGGMENPCLTFVT 280
           P FPYGGMENPCLTFVT
Sbjct: 259 PFFPYGGMENPCLTFVT 309
>31163
          Length = 381

 Score = 82.8 bits (203), Expect = 3e-16,   Method: Compositional matrix adjust.
 Identities = 38/60 (63%), Positives = 48/60 (80%)
 Frame = -3

Query: 378 AYSSIPYEKGFALLFYLEQLLGGPEVFLGFLKAYVKKFSYQSVTTDDWKSFLYSHFKDKV 437
           A+S +PYEKGFALLFYLE LLGGP V+  F+KAY+ KF  QS+T+  WK FL+S+F D+V
Sbjct: 283 AFSIVPYEKGFALLFYLENLLGGPAVYEPFMKAYINKFKNQSITSYQWKDFLFSYFHDQV 104
>20340
          Length = 617

 Score = 70.9 bits (172), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 54/182 (29%), Positives = 78/182 (42%), Gaps = 13/182 (7%)
 Frame = -1

Query: 260 LVLPPSFPYGGMENPCLTFVTPTLLAGDKSLSN--------VIAHEISHSWTGNLVTNKT 311
           LV  P FP G MEN  L     T L  D   S+        +I HE++H+W GNLVT   
Sbjct: 599 LVAAPDFPIGAMENWGLVIYRETALLVDTETSSFLKEYIALIIGHELAHNWFGNLVTMNW 420

Query: 312 WDHFWLNEGHTVYLERHICGRLFGEK--FRHFHALGGWGELQNTIK--TFGESHPFTXXX 367
           W H WL EG   ++E       F E   +  F +     +L   +K      SHP     
Sbjct: 419 WTHLWLKEGFASWIEYLCVDHCFPEYDIWTQFVS----NDLGRALKLDALNNSHPI--EI 258

Query: 368 XXXXXXXXXXAYSSIPYEKGFALLFYLEQLLGGPEVFLGFLKAYVKKFSYQSVTTDD-WK 426
                      + +I Y KG +++  L   +G  +   G + AY+++  Y S  T+D WK
Sbjct: 257 EVGNPSEVDEIFDAISYSKGASIINMLHDYIGDADFRKG-MTAYLQRHQYSSACTEDLWK 81

Query: 427 SF 428
           + 
Sbjct: 80  AL 75
>29830
          Length = 1148

 Score = 40.4 bits (93), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 35/109 (32%), Positives = 44/109 (40%), Gaps = 8/109 (7%)
 Frame = -3

Query: 255 GQYDLLVLPPSFPYGGMENPCLTFVTPTLL--------AGDKSLSNVIAHEISHSWTGNL 306
           GQY      P F  G MEN  L     TLL          +   + VIAHEI+H W GNL
Sbjct: 810 GQYR----NPDFNAGAMENWGLITYRETLLYKPGVTSKTDEMWAAEVIAHEIAHMWFGNL 643

Query: 307 VTNKTWDHFWLNEGHTVYLERHICGRLFGEKFRHFHALGGWGELQNTIK 355
           VT K  +         ++L    CG       R   + G W  L + I+
Sbjct: 642 VTPKMVELAVAERSLRLFLGLSQCGGFTPGMERDRRSRGQWPSLGDDIR 496
>26751
          Length = 491

 Score = 31.6 bits (70), Expect = 1.00,   Method: Composition-based stats.
 Identities = 43/160 (26%), Positives = 67/160 (41%), Gaps = 16/160 (10%)
 Frame = +3

Query: 164 PKELVALMSAIRDGEAPDPEDPSRKIYRFNQRVPI-PCYLIALVVGALESRQI----GPR 218
           PK+ V L +     E     D S+K+ +F +R PI   YL+A VVG  +  +     G  
Sbjct: 18  PKDRVILSNMPVVSETSLESDSSQKVMKF-ERTPIMSTYLLAFVVGEFDYVEAKDADGVL 194

Query: 219 TLVWSEKEQVEKSANEFSETESMLKIAED-LGGPYVWGQYDLLVLPPSFPYGGMENPCL- 276
             V++   + E+       +   L   +D  G  Y   + DL+ +   F  G MEN  L 
Sbjct: 195 IRVYTPLGKKEQGQFALEVSVKTLPFYKDYFGIAYPLPKMDLIAI-ADFSAGAMENWGLV 371

Query: 277 TFVTPTLLAGDKSLSNVIAHEIS---------HSWTGNLV 307
           T+    LL   K+ S  +   ++          +W GNLV
Sbjct: 372 TYRETALLVDPKNTSTRVRLWVALVVGRRAGVTTWFGNLV 491
>12737
          Length = 1026

 Score = 28.9 bits (63), Expect = 6.3,   Method: Compositional matrix adjust.
 Identities = 14/39 (35%), Positives = 19/39 (48%)
 Frame = +2

Query: 105 ISFETSPKSSALQWLTPEQTSGKQHPYLFSQCQAIHCRA 143
           IS  TS     ++WL P     + HP   SQC  + C+A
Sbjct: 314 ISTTTSHGIHEIRWLFPVNGIPEAHPVRDSQCAVVECQA 430
>00846
          Length = 4234

 Score = 28.5 bits (62), Expect = 7.4,   Method: Compositional matrix adjust.
 Identities = 19/50 (38%), Positives = 24/50 (48%), Gaps = 2/50 (4%)
 Frame = +3

Query: 81   GYKGSPMEISLPIALSKNQEIVIEISFETSPK--SSALQWLTPEQTSGKQ 128
            GY   P  ++ PIA S  Q I+I I  E S    S A+ W   +Q   KQ
Sbjct: 3900 GYVREPSRVTSPIAYSNMQVILISILCEKS*TT*SQAMHWDVKQQKRKKQ 4049
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|126012517|ref|NP_031952.2| small inducible cytokine
subfamily E, member 1 [Mus musculus]
         (319 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

12674                                                                 242   1e-64
17358                                                                 140   8e-34
33013                                                                 105   3e-23
36599                                                                  68   9e-14
18275                                                                  37   0.008
>12674
          Length = 829

 Score =  242 bits (618), Expect = 1e-64,   Method: Compositional matrix adjust.
 Identities = 108/170 (63%), Positives = 137/170 (80%)
 Frame = -2

Query: 149 AASTDSKPIDASRLDLRIGCIVTAKKHPDADSLYVEEVDVGEAAPRTVVSGLVNHVPLEQ 208
           A + + + +D SRLD RIG I   +KHPDAD+LYVE VD+GE  PRT+VSGLVNH+P+EQ
Sbjct: 630 AGAAEPEKMDVSRLDFRIGKITAVEKHPDADTLYVETVDLGEEKPRTIVSGLVNHIPIEQ 451

Query: 209 MQNRMVVLLCNLKPAKMRGVLSQAMVMCASSPEKVEILAPPNGSVPGDRITFDAFPGEPD 268
           MQNR+ V +CNLK +KMRGV S+ M+MCA + EKVEIL PP G VPGDRITFD +PG PD
Sbjct: 450 MQNRLAVFMCNLKASKMRGVSSEGMIMCAKN-EKVEILEPPPGVVPGDRITFDGYPGTPD 274

Query: 269 KELNPKKKIWEQIQPDLHTNAECVATYKGAPFEVKGKGVCRAQTMANSGI 318
           K+LNPKKK+WE ++PD+ TN E VAT+KGAPF+V+GKG+ +A T+ N+ I
Sbjct: 273 KQLNPKKKVWETLKPDIRTNGERVATFKGAPFKVEGKGIVKAPTLTNAEI 124
>17358
          Length = 635

 Score =  140 bits (352), Expect = 8e-34,   Method: Compositional matrix adjust.
 Identities = 69/129 (53%), Positives = 90/129 (69%), Gaps = 3/129 (2%)
 Frame = +2

Query: 147 SAAASTDSKPIDASRLDLRIGCIVTAKKHPDADSLYVEEVDVGEAAPRTVVSGLVNHVPL 206
           S  AS     +  +RLDLR+G I + KKHP+ADSLY+E VD+GE + RTV+SGL   VP+
Sbjct: 248 SGRASAAQDEVSPARLDLRVGKITSVKKHPEADSLYIESVDLGEESERTVISGLAGLVPM 427

Query: 207 EQMQNRMVVLLCNLKPAKMRGVLSQAMVMCAS--SPEKVEILAPPNGSVPGDRITFDAFP 264
           E++Q+R+ V LCNLKP KMRG+ S  M+MCAS   P  VE L PP GS PGDR+  + + 
Sbjct: 428 EELQDRLGVFLCNLKPVKMRGIESCGMLMCASVDDPRAVEPLNPPEGSSPGDRVFVEGYE 607

Query: 265 -GEPDKELN 272
            G PD++LN
Sbjct: 608 KGTPDEKLN 634
>33013
          Length = 277

 Score =  105 bits (261), Expect = 3e-23,   Method: Compositional matrix adjust.
 Identities = 42/78 (53%), Positives = 63/78 (80%)
 Frame = -1

Query: 161 RLDLRIGCIVTAKKHPDADSLYVEEVDVGEAAPRTVVSGLVNHVPLEQMQNRMVVLLCNL 220
           RLD+R+G ++   +HPDAD+LYV ++D+ EA PRT++SGLV  V +E++  R+V +LCNL
Sbjct: 256 RLDIRVGKVIEVARHPDADTLYVLKIDLAEAQPRTIISGLVKFVTVEELDQRLVAVLCNL 77

Query: 221 KPAKMRGVLSQAMVMCAS 238
           KP+KMRG++S+ MV+C S
Sbjct: 76  KPSKMRGIMSEGMVLCTS 23
>36599
          Length = 197

 Score = 68.2 bits (165), Expect(2) = 9e-14,   Method: Compositional matrix adjust.
 Identities = 32/47 (68%), Positives = 38/47 (80%)
 Frame = -3

Query: 234 VMCASSPEKVEILAPPNGSVPGDRITFDAFPGEPDKELNPKKKIWEQ 280
           VMCA + EKVEIL PP G VPGDRITFD +PG PDK+LNPK+K  ++
Sbjct: 159 VMCAKN-EKVEILEPPPGVVPGDRITFDGYPGTPDKQLNPKRKYGKR 22

 Score = 25.8 bits (55), Expect(2) = 9e-14,   Method: Compositional matrix adjust.
 Identities = 8/15 (53%), Positives = 13/15 (86%)
 Frame = -2

Query: 273 PKKKIWEQIQPDLHT 287
           P+KK+WE ++PD+ T
Sbjct: 46  PQKKVWETLKPDIRT 2
>18275
          Length = 476

 Score = 37.4 bits (85), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 28/83 (33%), Positives = 40/83 (48%), Gaps = 1/83 (1%)
 Frame = +3

Query: 34  LKQQVALLKEKAILQATMREEKKLRVENXXXXXXXXXXXXXXXXXXXHNGVEQVRVRLST 93
           LKQQ+++L+    L A   EE++L+VEN                    NGV+QV +    
Sbjct: 9   LKQQISVLQTATALSAGKGEEERLKVENAELRKEIEKVKLSLMVAEIRNGVKQVPLPQQR 188

Query: 94  PLQTNCT-ASESVVQSPSVATTA 115
           PL T+ T AS +V   P+ A  A
Sbjct: 189 PLSTSATQASNAVPDKPAQAPVA 257

 Score = 33.9 bits (76), Expect = 0.089,   Method: Compositional matrix adjust.
 Identities = 14/29 (48%), Positives = 19/29 (65%)
 Frame = +2

Query: 149 AASTDSKPIDASRLDLRIGCIVTAKKHPD 177
           A + + + +D SRLD RIG I   +KHPD
Sbjct: 389 AGAAEPEKMDVSRLDFRIGKITAVEKHPD 475
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|13385134|ref|NP_079944.1| signal peptidase complex
subunit 2 homolog [Mus musculus]
         (226 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

03006                                                                 241   1e-64
12651                                                                  28   3.8  
>03006
          Length = 1773

 Score =  241 bits (616), Expect = 1e-64,   Method: Compositional matrix adjust.
 Identities = 113/187 (60%), Positives = 149/187 (79%)
 Frame = +1

Query: 38  KWKIDDKPVKIDKWDGSAVKNSLDDSAKKVLLEKYKYVENFGLIDGRLTICTISCFFAIV 97
           KW I+DKP+KIDKWD +A+KNSLDDSAK VL++   YVEN GL+DGRL ICTI+  FA+ 
Sbjct: 40  KWSIEDKPIKIDKWDSAALKNSLDDSAKNVLIKDCGYVENHGLVDGRLFICTIAVAFAMF 219

Query: 98  ALIWDYMHPFPESKPVLALCVISYFVMMGILTIYTSYKEKSIFLVAHRKDPTGMDPDDIW 157
           AL+WDY+ PFPES+PVL +CV SYFV+MG+LT+YT+YKE+ IFL+AH KD  GMDPD+ W
Sbjct: 220 ALVWDYLRPFPESRPVLIICVTSYFVLMGVLTVYTTYKERGIFLLAHEKDRAGMDPDNEW 399

Query: 158 QLSSSLKRFDDKYTLKLTFISGRTKQQREAEFTKSIAKFFDHSGTLVMDAYEPEISRLHD 217
            LSSSL+++DD YTL +T+  G+T++ R  EFTKS+A FFD +G L  D + PE+ ++  
Sbjct: 400 TLSSSLRKYDDLYTLCMTYTDGKTRETRTTEFTKSVANFFDENGVLCSDIFSPEVDKMRA 579

Query: 218 SLATERK 224
           SL +E+K
Sbjct: 580 SLLSEKK 600
>12651
          Length = 515

 Score = 27.7 bits (60), Expect = 3.8,   Method: Compositional matrix adjust.
 Identities = 13/53 (24%), Positives = 26/53 (49%), Gaps = 8/53 (15%)
 Frame = -2

Query: 102 DYMHPFPESKPVLA--------LCVISYFVMMGILTIYTSYKEKSIFLVAHRK 146
           DY   FP +  +L          C++++ + +G++T+Y S  E S+    H+ 
Sbjct: 340 DYNLNFPNN*SILCSPSLWMSNACIVTFNLCLGLVTVYQSAAESSLAESEHKA 182
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|12963531|ref|NP_075633.1| non-POU-domain-containing,
octamer binding protein [Mus musculus]
         (473 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

08958                                                                 243   2e-64
17775                                                                  60   2e-09
06580                                                                  53   3e-07
28652                                                                  53   3e-07
11687                                                                  51   9e-07
23395                                                                  51   9e-07
00029                                                                  48   7e-06
02882                                                                  47   1e-05
02347                                                                  46   3e-05
02502                                                                  45   8e-05
13457                                                                  44   1e-04
10194                                                                  44   1e-04
02415                                                                  44   1e-04
30672                                                                  43   3e-04
19868                                                                  43   3e-04
16427                                                                  42   5e-04
08670                                                                  41   0.001
08816                                                                  39   0.004
20169                                                                  39   0.005
00556                                                                  39   0.006
00817                                                                  37   0.012
16016                                                                  37   0.016
28455                                                                  37   0.016
23655                                                                  36   0.030
02064                                                                  36   0.032
03406                                                                  36   0.043
31618                                                                  35   0.052
17681                                                                  35   0.052
12350                                                                  35   0.053
17175                                                                  35   0.073
13822                                                                  35   0.081
26197                                                                  34   0.12 
19556                                                                  33   0.26 
15503                                                                  32   0.38 
02809                                                                  32   0.42 
03000                                                                  32   0.43 
23322                                                                  32   0.51 
33504                                                                  31   1.4  
29243                                                                  30   1.6  
25746                                                                  30   2.2  
03200                                                                  30   2.6  
17623                                                                  30   2.6  
03678                                                                  29   4.1  
>08958
          Length = 680

 Score =  243 bits (619), Expect = 2e-64,   Method: Compositional matrix adjust.
 Identities = 116/219 (52%), Positives = 160/219 (73%)
 Frame = +2

Query: 61  LKNFRKPGEKTFTQRSRLFVGNLPPDITEEEMRKLFEKYGKAGEVFIHKDKGFGFIRLET 120
           +K +R+   K FT R RLFVGNL PD++E++ +KLF  +G+  E +++  +GFGFIRL+ 
Sbjct: 32  VKEYRR---KKFTGRCRLFVGNLTPDVSEDDFKKLFSPFGEVSEAYVNSGRGFGFIRLDY 202

Query: 121 RTLAEIVKVELDNMPLRGKQLRVRFACHSASLTVRNLPQYVSNELLEEAFSVFGQVERAV 180
           R  AE  K  LD +  +G+ LRVR+A H A+L V+NL  YVSNELLE+AF+ FG +ERA+
Sbjct: 203 RHNAEAAKAALDGLQRKGRSLRVRYATHGAALKVKNLHPYVSNELLEQAFTQFGDLERAI 382

Query: 181 VIVDDRGRPSGKGIVEFSGKPAARKALDRCSEGSFLLTTFPWPVTVEPMDQLDDEEGLPE 240
           VIVD+RGR +G+G+VEF  KP A++AL R +EG FL    P P+ VEP++  D+E+GLPE
Sbjct: 383 VIVDERGRSTGEGVVEFVRKPGAQQALRRINEGVFLFGADPKPIEVEPLEHKDEEDGLPE 562

Query: 241 KLVIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEM 279
           K + KN+Q+ KERE+ P FA  GSFE+E+ MRWK L E+
Sbjct: 563 KFLGKNEQYLKEREKDPHFAPKGSFEFEFGMRWKQLAEL 679
>17775
          Length = 1282

 Score = 60.5 bits (145), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 39/153 (25%), Positives = 76/153 (49%), Gaps = 17/153 (11%)
 Frame = -2

Query: 76   SRLFVGNLPPDITEEEMRKLFEKYGKAG---------EVFIHKDKGFGFIRLETRTLAEI 126
            + L+VG+L PD+TE     LFEK+  AG         ++   +  G+ ++  +    AE 
Sbjct: 1194 ASLYVGDLHPDVTEA---MLFEKFSTAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAER 1024

Query: 127  VKVELDNMPLRGKQLRVRFACHSASLT--------VRNLPQYVSNELLEEAFSVFGQVER 178
                ++   ++G+ +R+ ++    S+         ++NL + + N+ L + FS FG +  
Sbjct: 1023 ALDTMNFDTVKGRPIRIMWSQRDPSVRKSGVGNVFIKNLDKTIDNKALYDTFSAFGNILS 844

Query: 179  AVVIVDDRGRPSGKGIVEFSGKPAARKALDRCS 211
              +  D++G   G G V F  + AAR+A+D+ +
Sbjct: 843  CKIACDEQG-SKGYGFVHFETEEAARQAIDKVN 748

 Score = 38.9 bits (89), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 34/123 (27%), Positives = 52/123 (42%), Gaps = 24/123 (19%)
 Frame = -2

Query: 109 KDKGFGFIRLETRTLAEIVKVELDNMPLRGK---------------QLRVRFA------- 146
           K +GFGF+  E    AE    E++   + G+               +L+ RF        
Sbjct: 537 KSRGFGFVSFEEPEGAEKAVDEINGTEVSGRIIYCGRAQKRAERQAELKERFEKIKLERI 358

Query: 147 --CHSASLTVRNLPQYVSNELLEEAFSVFGQVERAVVIVDDRGRPSGKGIVEFSGKPAAR 204
                 +L V+NL   + +E L + FS FG +  A ++ +  GR  G G V FS    A 
Sbjct: 357 NRYQGVNLYVKNLDDSIDDERLRKEFSNFGTITSAKIMTEG-GRSKGFGFVCFSSPEEAT 181

Query: 205 KAL 207
           KA+
Sbjct: 180 KAV 172

 Score = 33.1 bits (74), Expect = 0.25,   Method: Compositional matrix adjust.
 Identities = 20/70 (28%), Positives = 32/70 (45%), Gaps = 4/70 (5%)
 Frame = -2

Query: 78  LFVGNLPPDITEEEMRKLFEKYGKAGEVFIHKD----KGFGFIRLETRTLAEIVKVELDN 133
           +F+ NL   I  + +   F  +G      I  D    KG+GF+  ET   A     +++ 
Sbjct: 924 VFIKNLDKTIDNKALYDTFSAFGNILSCKIACDEQGSKGYGFVHFETEEAARQAIDKVNG 745

Query: 134 MPLRGKQLRV 143
           M L GK++ V
Sbjct: 744 MLLNGKKVYV 715
>06580
          Length = 1597

 Score = 52.8 bits (125), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 35/104 (33%), Positives = 51/104 (49%), Gaps = 11/104 (10%)
 Frame = +1

Query: 54  NEGLTIDLKN-----FRKPGEKT----FTQRSRLFVGNLPPDITEEEMRKLFEKYGKA-G 103
           + GLT D  N     F++PG K     F   + L + N+PP ITEE+++  F  YG   G
Sbjct: 85  DAGLTKDFVNSPLHRFKRPGSKNCQNIFPPSAVLHLSNIPPSITEEQLQSWFTDYGTVRG 264

Query: 104 EVFIHKDKGFGFIRLETRTLAEIVKVELDNMPL-RGKQLRVRFA 146
             F  KD+    I+L +   A +  + + NM L     LRV F+
Sbjct: 265 FKFFQKDRKMALIQLNSVDEAILALIGMHNMQLGENSHLRVSFS 396
>28652
          Length = 918

 Score = 52.8 bits (125), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 47/154 (30%), Positives = 66/154 (42%), Gaps = 22/154 (14%)
 Frame = -2

Query: 77  RLFVGNLPPDITEEEMRKLFEKYGKA-GEVFIH--------KDKGFGFIRLETRTLAEIV 127
           RLFVGN+P   T+EE+ K FEK+ +   +V ++        K++GF F+  +T   A   
Sbjct: 485 RLFVGNIPKSKTKEEILKEFEKHSEGLMDVIVYGSADNPKLKNRGFAFLEYDTHKNASAA 306

Query: 128 KVELDNMPLRGKQLRV-------------RFACHSASLTVRNLPQYVSNELLEEAFSVFG 174
           K        R  Q  V                     L VRNL   V+ + L+E F  +G
Sbjct: 305 KRRFTTGRFRVWQCDVIVDWADLQEEPNEETMSKVKVLYVRNLTGDVTEDDLKEKFGAYG 126

Query: 175 QVERAVVIVDDRGRPSGKGIVEFSGKPAARKALD 208
           +VER   I D        G V +  +  A KALD
Sbjct: 125 KVERVKKIKD-------YGFVHYEDREDALKALD 45

 Score = 43.5 bits (101), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 37/149 (24%), Positives = 65/149 (43%), Gaps = 11/149 (7%)
 Frame = -2

Query: 78  LFVGNLPPDITEEEMRKLFEKYGKAGEVFIHKD------KGFGFIRLETRTLAEIVKVEL 131
           +F G +P DI E+E+  LFE  G   ++ +  D      +G+ F+   T+  A     + 
Sbjct: 725 VFCGKIPRDIFEDELIPLFEDCGTIWDLRLMMDPVSNLNRGYCFVTYTTKEAAAEAVKQH 546

Query: 132 DNMPLR-GKQLRVRFACHSASLTVRNLPQYVSNELLEEAFSVFGQVERAVVIVDDRGRPS 190
           D   +R GK+L+V  +  +  L V N+P+  + E + + F    +    V++      P 
Sbjct: 545 DGYEIRKGKKLKVNISIPNLRLFVGNIPKSKTKEEILKEFEKHSEGLMDVIVYGSADNPK 366

Query: 191 ----GKGIVEFSGKPAARKALDRCSEGSF 215
               G   +E+     A  A  R + G F
Sbjct: 365 LKNRGFAFLEYDTHKNASAAKRRFTTGRF 279

 Score = 40.4 bits (93), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 21/55 (38%), Positives = 33/55 (60%)
 Frame = -2

Query: 67  PGEKTFTQRSRLFVGNLPPDITEEEMRKLFEKYGKAGEVFIHKDKGFGFIRLETR 121
           P E+T ++   L+V NL  D+TE+++++ F  YGK   V   K K +GF+  E R
Sbjct: 227 PNEETMSKVKVLYVRNLTGDVTEDDLKEKFGAYGKVERV--KKIKDYGFVHYEDR 69
>11687
          Length = 676

 Score = 51.2 bits (121), Expect = 9e-07,   Method: Compositional matrix adjust.
 Identities = 38/150 (25%), Positives = 65/150 (43%), Gaps = 19/150 (12%)
 Frame = +3

Query: 77  RLFVGNLPPDITEEEMRKLFEKYGKAGEVFIHKD------KGFGFIRLETRTLAEIVKVE 130
           ++FVG +P ++ E E+RK+FE YG    + I +D      KG  F+   TR  A   +  
Sbjct: 153 KMFVGQIPRNMDENELRKMFEDYGPVHSLNILRDKNTGQSKGCCFVTFFTRKAALDAQNA 332

Query: 131 LDN---MPLRGKQLRVRFA----------CHSASLTVRNLPQYVSNELLEEAFSVFGQVE 177
           L N   MP+    ++++ A               L V  L + +S   +   F  FG ++
Sbjct: 333 LHNVKTMPMMHHPVQMKPADSEKRNGERNVEERKLFVGMLSKKLSENDVRMLFESFGSID 512

Query: 178 RAVVIVDDRGRPSGKGIVEFSGKPAARKAL 207
              V+ D  G   G   + F+ +  A  ++
Sbjct: 513 DCTVLRDSNGTSRGCAFITFASRQCAMNSI 602

 Score = 38.9 bits (89), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 20/65 (30%), Positives = 35/65 (53%), Gaps = 5/65 (7%)
 Frame = +3

Query: 65  RKPGEKTFTQRSRLFVGNLPPDITEEEMRKLFEKYGKAGEVFIHKD-----KGFGFIRLE 119
           ++ GE+   +R +LFVG L   ++E ++R LFE +G   +  + +D     +G  FI   
Sbjct: 399 KRNGERNVEER-KLFVGMLSKKLSENDVRMLFESFGSIDDCTVLRDSNGTSRGCAFITFA 575

Query: 120 TRTLA 124
           +R  A
Sbjct: 576 SRQCA 590
>23395
          Length = 1060

 Score = 51.2 bits (121), Expect = 9e-07,   Method: Compositional matrix adjust.
 Identities = 32/95 (33%), Positives = 47/95 (49%), Gaps = 6/95 (6%)
 Frame = -1

Query: 58  TIDLKNFRKPGEK----TFTQRSRLFVGNLPPDITEEEMRKLFEKYGKA-GEVFIHKDKG 112
           T  L  F++PG K     F   + L + N+PP ITEE+++  F  YG   G  F  KD+ 
Sbjct: 949 TSPLHRFKRPGSKNCQNIFPPSAVLHLSNIPPSITEEQLQSWFTDYGTVRGFKFFQKDRK 770

Query: 113 FGFIRLETRTLAEIVKVELDNMPL-RGKQLRVRFA 146
              I+L +   A +  + + NM L     LRV F+
Sbjct: 769 MALIQLNSVDEAILALIGMHNMQLGENSHLRVSFS 665
>00029
          Length = 2204

 Score = 48.1 bits (113), Expect = 7e-06,   Method: Compositional matrix adjust.
 Identities = 24/76 (31%), Positives = 41/76 (53%)
 Frame = -3

Query: 72   FTQRSRLFVGNLPPDITEEEMRKLFEKYGKAGEVFIHKDKGFGFIRLETRTLAEIVKVEL 131
            +    ++F+GNL  D   EE+R LFEKYG   E  + K+  FGF+ +  +  A+     L
Sbjct: 2148 YNMTIKIFIGNLGDDTDPEELRALFEKYGSVAECDVLKN--FGFVHMVKKGEADDAISNL 1975

Query: 132  DNMPLRGKQLRVRFAC 147
            +   + G+++RV  + 
Sbjct: 1974 NGYNIGGQRMRVELST 1927
>02882
          Length = 2876

 Score = 47.0 bits (110), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 35/115 (30%), Positives = 52/115 (45%), Gaps = 11/115 (9%)
 Frame = -1

Query: 43   IPANGQQASSQNEGLTID-----LKNFRKPGEKT----FTQRSRLFVGNLPPDITEEEMR 93
            +P  GQ     + GLT D     L  F++PG K     F   + L + N+PP +TEE+++
Sbjct: 2813 MPKEGQS----DAGLTKDFAGSPLHRFKRPGSKNCQNIFPPSAVLHLSNIPPSVTEEQIQ 2646

Query: 94   KLFEKYGKA-GEVFIHKDKGFGFIRLETRTLAEIVKVELDNMPL-RGKQLRVRFA 146
              F  YG   G  F  KD+    I +     A +  + + N  L     LRV F+
Sbjct: 2645 NWFADYGTVKGFKFFQKDRRMALIEMNNADEAVLSLIGMHNTQLGENSHLRVSFS 2481
>02347
          Length = 928

 Score = 46.2 bits (108), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 22/69 (31%), Positives = 39/69 (56%), Gaps = 1/69 (1%)
 Frame = -3

Query: 76  SRLFVGNLPPDITEEEMRKLFEKYGKAGEVFIHKD-KGFGFIRLETRTLAEIVKVELDNM 134
            +++VG+LPPD +E+E+ + F  YG    V++ ++  GF F+  E    A+     LD  
Sbjct: 746 GKIYVGDLPPDASEKEVERAFNYYGHLRNVWVARNPPGFAFVEFEDTRDADDAVRALDGT 567

Query: 135 PLRGKQLRV 143
            + G ++RV
Sbjct: 566 VVCGNRVRV 540
>02502
          Length = 1557

 Score = 44.7 bits (104), Expect = 8e-05,   Method: Compositional matrix adjust.
 Identities = 23/82 (28%), Positives = 38/82 (46%), Gaps = 4/82 (4%)
 Frame = -3

Query: 69   EKTFTQRSR----LFVGNLPPDITEEEMRKLFEKYGKAGEVFIHKDKGFGFIRLETRTLA 124
            ++ F Q S+    ++ G +   +TEE M   F+ +G   EV I KDKGF FIR   +  A
Sbjct: 1474 DEVFNQSSQTNCTVYCGGVNNGLTEELMHNTFKDFGSILEVRIFKDKGFAFIRFNNKDAA 1295

Query: 125  EIVKVELDNMPLRGKQLRVRFA 146
                  +    +  + +R  + 
Sbjct: 1294 TNAICTIHGTVINDQVVRCSWG 1229
>13457
          Length = 4857

 Score = 44.3 bits (103), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 37/126 (29%), Positives = 55/126 (43%), Gaps = 18/126 (14%)
 Frame = -1

Query: 71   TFTQRSRLFVGNLPPDITEEEMRKLFEKYGKAGEVFIHKD-----KGFGFIRLETRTLAE 125
            T  +  +LFVG L    TEE++R+LF  YG   E  I +D     KG  F++  T + A+
Sbjct: 3423 TIGEDRKLFVGMLNKQQTEEDVRQLFHPYGAIEECTILRDQNGNSKGCAFVKYSTHSEAQ 3244

Query: 126  IVKVEL---DNMPLRGKQLRVRFACHSASLTVRNLPQ----------YVSNELLEEAFSV 172
                 L     MP     L V+FA       +R + Q          +  N++   A+  
Sbjct: 3243 AAINALHGSQTMPGASSSLVVKFADTEKERQLRRMQQMAGPLGLLNPFTLNQIGGTAYGT 3064

Query: 173  FGQVER 178
            F QVE+
Sbjct: 3063 FPQVEQ 3046
>10194
          Length = 1278

 Score = 43.9 bits (102), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 31/90 (34%), Positives = 47/90 (52%), Gaps = 6/90 (6%)
 Frame = -3

Query: 70  KTFTQRSRLFVGNLPPDITEEEMRKLFEKYGKAGEVFIHKD------KGFGFIRLETRTL 123
           K   +RS +FVGNLP DI EE +R  FE  G    + + +D      KG  +I  ++   
Sbjct: 421 KNLDKRS-VFVGNLPFDIEEESVRSHFEDCGDVENIRVVRDRKTNLGKGICYILFKSADS 245

Query: 124 AEIVKVELDNMPLRGKQLRVRFACHSASLT 153
             +  ++L+N  L  +Q+RV+  C  AS T
Sbjct: 244 VSLA-LKLNNSELEKRQIRVQ-RCKDASKT 161

 Score = 30.8 bits (68), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 42/159 (26%), Positives = 64/159 (40%), Gaps = 29/159 (18%)
 Frame = -3

Query: 78  LFVGNLPPDITEEEMRKLFEKYGKAGEV-----------------FIHKD------KGFG 114
           +FVGN+P    ++++ +LF+++GK   V                  I KD          
Sbjct: 706 VFVGNVPLKTDKKKLARLFKQFGKIENVRFRCAPVGDPTTKKRVAVITKDFHEKRHNISA 527

Query: 115 FIRLETRTLAEIVKVELDNMPLRGKQLRVRFACHSA------SLTVRNLPQYVSNELLEE 168
           +I  +    A+   + L+   + G  LRV  A  S       S+ V NLP  +  E +  
Sbjct: 526 YICFKEDEAAKQA-LTLNGHVIDGLHLRVDSAKLSLKNLDKRSVFVGNLPFDIEEESVRS 350

Query: 169 AFSVFGQVERAVVIVDDRGRPSGKGIVEFSGKPAARKAL 207
            F   G VE  + +V DR    GKGI     K A   +L
Sbjct: 349 HFEDCGDVEN-IRVVRDRKTNLGKGICYILFKSADSVSL 236
>02415
          Length = 2763

 Score = 43.9 bits (102), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 19/59 (32%), Positives = 33/59 (55%), Gaps = 6/59 (10%)
 Frame = -1

Query: 73   TQRSRLFVGNLPPDITEEEMRKLFEKYGKAGEVFIHKD------KGFGFIRLETRTLAE 125
            T  +++FVG LP   T+  +R+ F+K+G   E  +  D      +G+GF+ +  RT A+
Sbjct: 1935 TTYTKIFVGGLPYHTTDHSLREYFDKFGDIDEAVVITDRQTGKSRGYGFVTMADRTGAD 1759
>30672
          Length = 877

 Score = 42.7 bits (99), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 38/103 (36%), Positives = 47/103 (45%), Gaps = 8/103 (7%)
 Frame = +3

Query: 148 HSASLTVRNLPQYVSNELLEEAFSVFGQVERAVVIVDDR-GRPSGKGIVEFSGKPAARKA 206
            S +L VRNLP   SNE L EAF   G ++ A V+     G+  G G V+FS    A KA
Sbjct: 6   QSKTLFVRNLPFETSNEKLLEAFEQVGPLKTAFVVAGKEPGKCRGFGYVQFSMLEDAIKA 185

Query: 207 LD---RCS----EGSFLLTTFPWPVTVEPMDQLDDEEGLPEKL 242
            D    CS      SF  T   W    +   +  D  GL +KL
Sbjct: 186 KDTVTHCSGRKISLSFADTKKSWKTKQKGGTETSDALGLGKKL 314

 Score = 33.9 bits (76), Expect = 0.15,   Method: Compositional matrix adjust.
 Identities = 21/79 (26%), Positives = 39/79 (49%), Gaps = 6/79 (7%)
 Frame = +3

Query: 74  QRSRLFVGNLPPDITEEEMRKLFEKYGKAGEVFI------HKDKGFGFIRLETRTLAEIV 127
           Q   LFV NLP + + E++ + FE+ G     F+       K +GFG+++     L + +
Sbjct: 6   QSKTLFVRNLPFETSNEKLLEAFEQVGPLKTAFVVAGKEPGKCRGFGYVQFS--MLEDAI 179

Query: 128 KVELDNMPLRGKQLRVRFA 146
           K +       G+++ + FA
Sbjct: 180 KAKDTVTHCSGRKISLSFA 236
>19868
          Length = 434

 Score = 42.7 bits (99), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 40/145 (27%), Positives = 64/145 (44%), Gaps = 17/145 (11%)
 Frame = +2

Query: 77  RLFVGNLPPDITEEEMRKLFEKYGKAGEVFIHKD------KGFGFIRL-----ETRTLAE 125
           ++FVG L    + E +R  F K+G+  EV + KD      +GFGFI         + LA+
Sbjct: 2   KMFVGGLSWQTSPESLRDYFNKFGEITEVMVMKDPTTRRSRGFGFITFGDPASVDKVLAQ 181

Query: 126 IVKVELDNMPLRGK-----QLRVRFACHSASLTVRNLPQYVSNELLEEAFSVFGQVERAV 180
               ELD   +  K     +   R    +  + V  L    + E ++  F  FG +E A+
Sbjct: 182 ATH-ELDGKKIDPKVAFPRRAHPRMVTRTKKIFVGGLSAPTTLEDVKNYFEQFGPIEDAM 358

Query: 181 VIVDDR-GRPSGKGIVEFSGKPAAR 204
           ++ D +  R  G G V  S +  +R
Sbjct: 359 LMFDKQTNRHRGFGFVTISKRRHSR 433
>16427
          Length = 1313

 Score = 42.4 bits (98), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 26/80 (32%), Positives = 39/80 (48%), Gaps = 6/80 (7%)
 Frame = +1

Query: 77  RLFVGNLPPDITEEEMRKLFEKYGKAGEVFIHKDK------GFGFIRLETRTLAEIVKVE 130
           +LFVG L  +I E+ + + F K+G+  E  + +DK      GFGF+  E    AE     
Sbjct: 139 KLFVGGLAEEIDEKVLEREFSKFGRITESMVIRDKVRQVSRGFGFVTYENPMDAEEAVKH 318

Query: 131 LDNMPLRGKQLRVRFACHSA 150
           +D   + GK+L V  A    
Sbjct: 319 MDGKEILGKKLHVEDAVRGG 378
>08670
          Length = 1307

 Score = 40.8 bits (94), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 21/70 (30%), Positives = 36/70 (51%)
 Frame = +2

Query: 76   SRLFVGNLPPDITEEEMRKLFEKYGKAGEVFIHKDKGFGFIRLETRTLAEIVKVELDNMP 135
            + L+VGN+ P +TE+ + ++F K+G    V +  +K   FI  + +  A      L N  
Sbjct: 953  TALWVGNVLPQVTEKRLTQMFAKHGPVASVRMLPEKYCAFINYKLKESAGRAMQYLQNQE 1132

Query: 136  LRGKQLRVRF 145
              G+ L +RF
Sbjct: 1133 CEGQHLLIRF 1162
>08816
          Length = 566

 Score = 38.9 bits (89), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 20/59 (33%), Positives = 36/59 (61%)
 Frame = +1

Query: 150 ASLTVRNLPQYVSNELLEEAFSVFGQVERAVVIVDDRGRPSGKGIVEFSGKPAARKALD 208
            ++TVRN+P  ++ + L E F   G V+ + +++D +GRPSG  +V F     A +A++
Sbjct: 49  CTVTVRNVPFSLTWQELRERFQDIGDVKFSEILMD-QGRPSGDAVVRFGTSADAMRAIN 222
>20169
          Length = 1364

 Score = 38.9 bits (89), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 26/101 (25%), Positives = 44/101 (43%), Gaps = 1/101 (0%)
 Frame = -1

Query: 44   PANGQQASSQNEGLTIDLKNFRKPGEKTFTQRSRLFVGNLPPDITEEEMRKLFEKYGKAG 103
            P   Q  + +   LT   K   +   + F+   +++VG L     ++E+   F KYG   
Sbjct: 1160 PIAAQHTAGKKGCLTGRRKEMSR--HRDFSLDCKVYVGELGHGCAKQELEDKFAKYGPLK 987

Query: 104  EVFI-HKDKGFGFIRLETRTLAEIVKVELDNMPLRGKQLRV 143
             V++  +  GF F+  E    AE     LD   + G++ RV
Sbjct: 986  NVWVARRPAGFAFVEFEDNRDAEDAVQALDGARINGRRARV 864
>00556
          Length = 2189

 Score = 38.5 bits (88), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 28/90 (31%), Positives = 40/90 (44%), Gaps = 12/90 (13%)
 Frame = +3

Query: 67  PGEKTFTQRSRLFVGNLPPDITEEEMRKLFEKYGKAG-----------EVFIHKDKGFGF 115
           PG     Q  RL+VGN+P  +TEE M   F    K              V I+ DK F F
Sbjct: 402 PGSAMSRQARRLYVGNIPFGVTEESMMDFFNHQMKITGLAQAEGDPVIAVHINLDKNFAF 581

Query: 116 IRLETRTLAEIVK-VELDNMPLRGKQLRVR 144
             LE R++ E  + +  D +    + L++R
Sbjct: 582 --LELRSVDETTQALAFDGIAYETQPLKIR 665
>00817
          Length = 2606

 Score = 37.4 bits (85), Expect = 0.012,   Method: Compositional matrix adjust.
 Identities = 17/46 (36%), Positives = 24/46 (52%), Gaps = 6/46 (13%)
 Frame = -2

Query: 77   RLFVGNLPPDITEEEMRKLFEKYGKAGEVFIHKD------KGFGFI 116
            ++F+G + PD  E  +R  FEKYG   E  + KD      + F FI
Sbjct: 2548 KVFIGGMHPDTDESSLRSYFEKYGDIRECIVVKDPATKRSRCFSFI 2411
>16016
          Length = 1364

 Score = 37.0 bits (84), Expect = 0.016,   Method: Compositional matrix adjust.
 Identities = 17/46 (36%), Positives = 24/46 (52%), Gaps = 6/46 (13%)
 Frame = -2

Query: 77   RLFVGNLPPDITEEEMRKLFEKYGKAGEVFIHKD------KGFGFI 116
            ++F+G + PD  E  +R  FEKYG   E  + KD      + F FI
Sbjct: 1306 KVFIGGMHPDTDESSLRSYFEKYGDIRECIVVKDPATKRSRCFSFI 1169
>28455
          Length = 573

 Score = 37.0 bits (84), Expect = 0.016,   Method: Compositional matrix adjust.
 Identities = 23/94 (24%), Positives = 44/94 (46%), Gaps = 5/94 (5%)
 Frame = -1

Query: 71  TFTQRSRLFVGNLPPDITEEEMRKLFEKYGKAGEVFI-----HKDKGFGFIRLETRTLAE 125
           T  ++++LFV NLP   + E +  +F+++GK  +V +        KG  ++  ET  +A 
Sbjct: 555 TSLEKNKLFVKNLPFTCSAEALETIFKEHGKVKDVRLVTYRSGASKGLAYVEFETEEMAT 376

Query: 126 IVKVELDNMPLRGKQLRVRFACHSASLTVRNLPQ 159
              ++ D +         +   H  S+ + N PQ
Sbjct: 375 QAVMKTDGL---------QVGDHMISVAISNPPQ 301

 Score = 30.8 bits (68), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 19/56 (33%), Positives = 27/56 (48%)
 Frame = -1

Query: 152 LTVRNLPQYVSNELLEEAFSVFGQVERAVVIVDDRGRPSGKGIVEFSGKPAARKAL 207
           L V+NLP   S E LE  F   G+V+   ++    G   G   VEF  +  A +A+
Sbjct: 534 LFVKNLPFTCSAEALETIFKEHGKVKDVRLVTYRSGASKGLAYVEFETEEMATQAV 367
>23655
          Length = 929

 Score = 36.2 bits (82), Expect = 0.030,   Method: Compositional matrix adjust.
 Identities = 20/61 (32%), Positives = 34/61 (55%), Gaps = 4/61 (6%)
 Frame = -1

Query: 73  TQRSRLFVGNLPPDITEEEMRKLFEKYGKAGEVFIHKDKGFG----FIRLETRTLAEIVK 128
           T R ++FVG +  D TE+ +R  F ++G+   V + +DKG G    F+ L + T   + K
Sbjct: 914 TVREKMFVGGVKEDTTEDMIRDTFNEFGEITGVDLIQDKGTGKNRDFVSLPSVTTTPLTK 735

Query: 129 V 129
           +
Sbjct: 734 L 732
>02064
          Length = 1195

 Score = 36.2 bits (82), Expect = 0.032,   Method: Compositional matrix adjust.
 Identities = 18/60 (30%), Positives = 38/60 (63%)
 Frame = +1

Query: 149 SASLTVRNLPQYVSNELLEEAFSVFGQVERAVVIVDDRGRPSGKGIVEFSGKPAARKALD 208
           + ++ V+NLP  ++ + L E F   G V+ + + +D +GR +G+G+V F+ +  A +A++
Sbjct: 76  NCTVQVKNLPYAITWQDLRERFQEIGVVKYSEITMD-KGRSTGQGLVRFATEDDAVRAIN 252
>03406
          Length = 1292

 Score = 35.8 bits (81), Expect = 0.043,   Method: Compositional matrix adjust.
 Identities = 37/146 (25%), Positives = 66/146 (45%), Gaps = 11/146 (7%)
 Frame = +3

Query: 77  RLFVGNLPPDITEEEMRKLFEKYGKAGEVFIHKD------KGFGFIRL-ETRTLAEIVKV 129
           ++FVG L  +   + +R+ FEK+G+     +  D      +GFGF+   E  T+  +VK 
Sbjct: 243 KIFVGGLSWETXSKHLREYFEKFGEVTSCTLKTDLDSGKSRGFGFVVFKEAATVDAVVKN 422

Query: 130 ELDNMPLRGKQLRVRFACHSASLT---VRNLPQYVSNELLEEAFSVFGQVERAVVIVDD- 185
           +     L+G+++  + A     +    V  L   V  E +E  F+ FG+V    +  D  
Sbjct: 423 K--EHKLQGRKIDPKPANPRKGMRKIFVGKLDPGVPQEDVESYFAKFGKVVNVELPYDKV 596

Query: 186 RGRPSGKGIVEFSGKPAARKALDRCS 211
           + +      VEF      +K L++ S
Sbjct: 597 KDQRRAFCFVEFDNDKTVKKVLEQTS 674
>31618
          Length = 716

 Score = 35.4 bits (80), Expect = 0.052,   Method: Compositional matrix adjust.
 Identities = 18/46 (39%), Positives = 26/46 (56%), Gaps = 6/46 (13%)
 Frame = +1

Query: 77  RLFVGNLPPDITEEEMRKLFEKYGKAGEVFIHKD------KGFGFI 116
           +LFVG L  + TE+E+R  F KYG+   + +  D      +GF FI
Sbjct: 295 KLFVGGLSWETTEKELRDHFGKYGEIESINVKTDPQTGRSRGFAFI 432
>17681
          Length = 964

 Score = 35.4 bits (80), Expect = 0.052,   Method: Compositional matrix adjust.
 Identities = 18/81 (22%), Positives = 37/81 (45%), Gaps = 6/81 (7%)
 Frame = +2

Query: 72  FTQRSRLFVGNLPPDITEEEMRKLFEKYGKAGEVFIHKD------KGFGFIRLETRTLAE 125
            +    +FVG+L P+I  E +R+ F  +G+     I +D      KG+ F+    +  AE
Sbjct: 20  ISSHHHIFVGDLSPEIETETLREAFAPFGEISNCRIVRDPQTMKSKGYAFVSFVKKAEAE 199

Query: 126 IVKVELDNMPLRGKQLRVRFA 146
                ++   +  + +R  ++
Sbjct: 200 NAIQAMNGQWIGSRSIRTNWS 262
>12350
          Length = 975

 Score = 35.4 bits (80), Expect = 0.053,   Method: Compositional matrix adjust.
 Identities = 18/61 (29%), Positives = 34/61 (55%), Gaps = 1/61 (1%)
 Frame = -2

Query: 66  KPGEKTFTQRSRLFVGNLPPDITEEEMRKLFEKYGKAGEVFIHKD-KGFGFIRLETRTLA 124
           K G +    R ++FVG    D+T +++R+ F K+G+  +VFI +  + F F+      +A
Sbjct: 389 KEGAQQLMNR-KIFVGRCTDDMTADDLRQFFSKFGEVVDVFIPRPFRAFAFVSFADPEVA 213

Query: 125 E 125
           +
Sbjct: 212 Q 210
>17175
          Length = 512

 Score = 35.0 bits (79), Expect = 0.073,   Method: Compositional matrix adjust.
 Identities = 12/24 (50%), Positives = 19/24 (79%)
 Frame = -3

Query: 77  RLFVGNLPPDITEEEMRKLFEKYG 100
           ++FVG +P ++ E E+RK+FE YG
Sbjct: 87  KMFVGQIPRNMDENELRKMFEDYG 16
>13822
          Length = 963

 Score = 34.7 bits (78), Expect = 0.081,   Method: Compositional matrix adjust.
 Identities = 30/117 (25%), Positives = 52/117 (44%), Gaps = 4/117 (3%)
 Frame = -1

Query: 77  RLFVGNLPPDITEEEMRKLFEKYGKAGEVFI----HKDKGFGFIRLETRTLAEIVKVELD 132
           RL V N+P    E ++R+L   +G   +V I       KGFGF+       AE  + +++
Sbjct: 339 RLHVSNIPFRFREADLRQLLGPFGTILDVEIIFNERGSKGFGFVTFAHSAEAERARDKMN 160

Query: 133 NMPLRGKQLRVRFACHSASLTVRNLPQYVSNELLEEAFSVFGQVERAVVIVDDRGRP 189
              + G+++ V  A      T R + + V+   +  A ++ G       +   RGRP
Sbjct: 159 GTVVEGRKIEVNNA------TARVMTKKVAAPSIPNAAALRG-------VALTRGRP 28
>26197
          Length = 1365

 Score = 34.3 bits (77), Expect = 0.12,   Method: Compositional matrix adjust.
 Identities = 18/59 (30%), Positives = 32/59 (54%), Gaps = 7/59 (11%)
 Frame = -2

Query: 77   RLFVGNLPPDITEEEMRKLFEKYGKAGEVFIHKD------KGFGFIRL-ETRTLAEIVK 128
            ++FVG L  + + + +R+ FEK+G+     +  D      +GFGF+   E  T+  +VK
Sbjct: 1295 KIFVGGLSWETSSKHLREYFEKFGEVTSCTLKTDLDSGKSRGFGFVVFKEAVTVDAVVK 1119

 Score = 30.8 bits (68), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 20/74 (27%), Positives = 39/74 (52%), Gaps = 7/74 (9%)
 Frame = -3

Query: 77   RLFVGNLPPDITEEEMRKLFEKYGKAGEVFIHKDK------GFGFIRLET-RTLAEIVKV 129
            R FVG L P + +E++   F K+GK   V +  DK       F F+  +  +T+ ++  +
Sbjct: 1048 RFFVGKLDPGVPQEDVESYFAKFGKVVNVELPYDKVKDQRRAFCFVEFDNDKTVKKV--L 875

Query: 130  ELDNMPLRGKQLRV 143
            E  +  + G+++R+
Sbjct: 874  EQTSHKIGGQEVRI 833
>19556
          Length = 917

 Score = 33.1 bits (74), Expect = 0.26,   Method: Compositional matrix adjust.
 Identities = 24/88 (27%), Positives = 43/88 (48%), Gaps = 11/88 (12%)
 Frame = -1

Query: 74  QRSRLFVGNLPPDITEEEMRKLFEKYGKAGEVFIHKDKGFGFIRLETRTLAEI------- 126
           QR   F+G L   +TEEE+ + F ++G+   V I K +  G   +++RT A +       
Sbjct: 836 QRKENFIGGLVKGVTEEELMEKFSRFGQVSNVDI-KTRTNG---IDSRTFAYVNLTAEEN 669

Query: 127 ----VKVELDNMPLRGKQLRVRFACHSA 150
                    +N   +G QL++++A  S+
Sbjct: 668 GFKKCFTAYNNTKWKGGQLKLQYAKESS 585
>15503
          Length = 570

 Score = 32.3 bits (72), Expect = 0.38,   Method: Compositional matrix adjust.
 Identities = 18/45 (40%), Positives = 24/45 (53%), Gaps = 3/45 (6%)
 Frame = +1

Query: 78  LFVGNLPPDITEEEMRKLFEKYGKAGEVFIHK---DKGFGFIRLE 119
           L+V NLP  IT EEM  +F KYG   ++ +      KG  F+  E
Sbjct: 154 LYVKNLPYKITAEEMYDIFGKYGAIRQIRVGNTPETKGTAFVVYE 288
>02809
          Length = 1475

 Score = 32.3 bits (72), Expect = 0.42,   Method: Compositional matrix adjust.
 Identities = 18/64 (28%), Positives = 30/64 (46%), Gaps = 1/64 (1%)
 Frame = -1

Query: 70   KTFTQRSRLFVGNLPPDITEEEMRKLFEKYGKAGEVFIHKD-KGFGFIRLETRTLAEIVK 128
            + F+   +++VG L     ++E+   F KYG    V++ +   GF F+  E    AE   
Sbjct: 1352 RDFSLDCKVYVGELGHGCAKQELEDKFAKYGPLKNVWVARRPAGFAFVEFEDNRDAEDAV 1173

Query: 129  VELD 132
              LD
Sbjct: 1172 QALD 1161
>03000
          Length = 778

 Score = 32.3 bits (72), Expect = 0.43,   Method: Compositional matrix adjust.
 Identities = 14/38 (36%), Positives = 24/38 (63%)
 Frame = +3

Query: 77  RLFVGNLPPDITEEEMRKLFEKYGKAGEVFIHKDKGFG 114
           ++FVG +  D TE+ +R  F ++G+   V + +DKG G
Sbjct: 363 KMFVGGVKEDTTEDMIRDTFNEFGEITGVDLIQDKGTG 476
>23322
          Length = 471

 Score = 32.0 bits (71), Expect = 0.51,   Method: Compositional matrix adjust.
 Identities = 14/38 (36%), Positives = 24/38 (63%)
 Frame = -2

Query: 77  RLFVGNLPPDITEEEMRKLFEKYGKAGEVFIHKDKGFG 114
           ++FVG +  D TE+ +R  F ++G+   V + +DKG G
Sbjct: 407 KMFVGGVKEDTTEDMIRDTFNEFGEITGVDLIQDKGTG 294
>33504
          Length = 282

 Score = 30.8 bits (68), Expect = 1.4,   Method: Composition-based stats.
 Identities = 13/48 (27%), Positives = 27/48 (56%)
 Frame = +1

Query: 65  RKPGEKTFTQRSRLFVGNLPPDITEEEMRKLFEKYGKAGEVFIHKDKG 112
           +K     +   + +F+G LP D+TE ++  +F +YG+   + + +DK 
Sbjct: 136 KKSWHDEYKDSAWVFIGGLPYDLTEGDIICVFSQYGEIVNINLVRDKA 279
>29243
          Length = 1147

 Score = 30.4 bits (67), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 19/65 (29%), Positives = 31/65 (47%)
 Frame = +2

Query: 153 TVRNLPQYVSNELLEEAFSVFGQVERAVVIVDDRGRPSGKGIVEFSGKPAARKALDRCSE 212
           +VRN P YV+     E+++ +                   GI+E   +P A+K LD C +
Sbjct: 251 SVRNGPDYVNEPCSLESYNWY------------------VGIME---RPVAQKXLDTCPD 367

Query: 213 GSFLL 217
           G+FL+
Sbjct: 368 GTFLI 382
>25746
          Length = 475

 Score = 30.0 bits (66), Expect = 2.2,   Method: Compositional matrix adjust.
 Identities = 10/27 (37%), Positives = 19/27 (70%)
 Frame = +1

Query: 74  QRSRLFVGNLPPDITEEEMRKLFEKYG 100
           + + ++V  LP D+T+E+ ++L  KYG
Sbjct: 67  KSTHVYVSGLPSDLTDEQFQELMSKYG 147
>03200
          Length = 657

 Score = 29.6 bits (65), Expect = 2.6,   Method: Compositional matrix adjust.
 Identities = 16/76 (21%), Positives = 32/76 (42%)
 Frame = -1

Query: 87  ITEEEMRKLFEKYGKAGEVFIHKDKGFGFIRLETRTLAEIVKVELDNMPLRGKQLRVRFA 146
           +TE+ ++  F  +G    + I +++  GF+  E    A+     ++   +   QL+V  A
Sbjct: 459 VTEDILKSAFSNFGNIVNINIERERNNGFVTFEKMESADQAIANMNGSMISNVQLKVMMA 280

Query: 147 CHSASLTVRNLPQYVS 162
               S    N P   +
Sbjct: 279 RRQPSFDSVNDPSTTT 232
>17623
          Length = 687

 Score = 29.6 bits (65), Expect = 2.6,   Method: Compositional matrix adjust.
 Identities = 16/49 (32%), Positives = 26/49 (53%)
 Frame = -1

Query: 212 EGSFLLTTFPWPVTVEPMDQLDDEEGLPEKLVIKNQQFHKEREQPPRFA 260
            GSF+LT   W    + +  L DE GLP++L  ++ +   E  + P F+
Sbjct: 504 SGSFMLTLCSWGRRTKLVTSLSDEIGLPDRL--RSSR*MLESRE*PNFS 364
>03678
          Length = 847

 Score = 29.3 bits (64), Expect = 4.1,   Method: Compositional matrix adjust.
 Identities = 15/42 (35%), Positives = 23/42 (54%)
 Frame = -3

Query: 66  KPGEKTFTQRSRLFVGNLPPDITEEEMRKLFEKYGKAGEVFI 107
           KP E+T      +FVGN PP ++E +   LF+  G+   V +
Sbjct: 608 KPPERT------VFVGNTPPWLSEXDFEXLFKCCGEVERVIL 501
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|30794476|ref|NP_068680.1| protein kinase, cAMP
dependent regulatory, type I, alpha [Mus musculus]
         (381 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

08195                                                                 242   2e-64
27710                                                                 238   2e-63
18204                                                                 104   7e-23
20517                                                                  49   2e-06
27148                                                                  37   0.012
18885                                                                  32   0.51 
19667                                                                  32   0.56 
>08195
          Length = 2165

 Score =  242 bits (617), Expect = 2e-64,   Method: Compositional matrix adjust.
 Identities = 145/380 (38%), Positives = 205/380 (53%), Gaps = 31/380 (8%)
 Frame = -3

Query: 30   LLKDSIVQLCTTRPERPMAFLREYFERLE------------------KEEARQIQCLQKT 71
            LL++  V     RP   + F   YF RL                    +    I     T
Sbjct: 1998 LLQEFTVAALRERPSDLVDFAASYFNRLRLLNGDAVDPKCFTGGVRFSQTGSHILAHNGT 1819

Query: 72   GIRTDSREDE--ISPPPPNPVVKGRRRRGAISAEVY---TEEDAASYVRKVIPKDYKTMA 126
              + +S +DE  + PPP N     R RR ++SAE Y   T+ED     + V PK      
Sbjct: 1818 FAQNNSDDDEAMLEPPPSN---TARFRRKSVSAEAYNPETDEDGGE-AKIVNPKSDIQRQ 1651

Query: 127  ALAKAIEKNVLFSHLDDNERSDIFDAMFPVSFIAGETVIQQGDEGDNFYVIDQGEMDVYV 186
             LA  ++  +LF  LD  +  ++ DAMF  S   GE +I QGD+GDNFYVID G  D+YV
Sbjct: 1650 RLADVVKNILLFRSLDPEQMQEVLDAMFEKSVQPGEHIIDQGDDGDNFYVIDSGTYDIYV 1471

Query: 187  NNE-WATSVGE---GGSFGELALIYGTPRAATVKAKTNVKLWGIDRDSYRRILMGSTLRK 242
            + E  A  VG     G FGELAL+Y  PRAAT+ A +   +W +DR ++RRI++ +  +K
Sbjct: 1470 DVEGQAKLVGNYDNSGFFGELALMYNMPRAATIIASSTGTIWALDRTTFRRIVLKTAFQK 1291

Query: 243  RKMYEEFLSKVSILESLDKWERLTVADALEPVQFEDGQKIVVQGEPGDEFFIILEGTAAV 302
            RK YE  L  V +L+SLD +ER+ VADAL+   +EDG +I+ QG+  D  + +  G   +
Sbjct: 1290 RKKYESLLESVPLLKSLDLYERMNVADALQTRTYEDGVQIIKQGDAADVMYFVESGQVRI 1111

Query: 303  LQRRSENEE----FVEVGRLGPSDYFGEIALLMNRPRAATVVARGPLKCVKLDRPRFERV 358
                 E+ +      +V  L    YFGE+AL+ ++PRAA+  A+G +KC  LD   FER+
Sbjct: 1110 AMTNKESTDPSAGETDVTVLEKGGYFGELALITHQPRAASAYAQGTVKCAVLDVHAFERL 931

Query: 359  LGPCSDILKRNIQQYNSFVS 378
            +GPC D+LKRNI  Y+S +S
Sbjct: 930  MGPCMDVLKRNIDDYDSQIS 871
>27710
          Length = 429

 Score =  238 bits (608), Expect = 2e-63,   Method: Compositional matrix adjust.
 Identities = 112/142 (78%), Positives = 128/142 (90%)
 Frame = +2

Query: 162 ETVIQQGDEGDNFYVIDQGEMDVYVNNEWATSVGEGGSFGELALIYGTPRAATVKAKTNV 221
           E +IQQGDEGDNFYVID GE+DV+VN+E  T++ EGGSFGELALIYGTPRAATV+AK++V
Sbjct: 2   ENIIQQGDEGDNFYVIDVGEVDVFVNSELVTTISEGGSFGELALIYGTPRAATVRAKSDV 181

Query: 222 KLWGIDRDSYRRILMGSTLRKRKMYEEFLSKVSILESLDKWERLTVADALEPVQFEDGQK 281
           KLWGIDRDSYRRILMGST+RKRKMYEEFLS+VSILESLDKWERLTVAD+LE   F+DG+ 
Sbjct: 182 KLWGIDRDSYRRILMGSTIRKRKMYEEFLSRVSILESLDKWERLTVADSLETCAFDDGET 361

Query: 282 IVVQGEPGDEFFIILEGTAAVL 303
           IV QG  GD+F+IILEG A VL
Sbjct: 362 IVKQGAAGDDFYIILEGCAVVL 427

 Score = 53.5 bits (127), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 38/99 (38%), Positives = 52/99 (52%)
 Frame = +2

Query: 280 QKIVVQGEPGDEFFIILEGTAAVLQRRSENEEFVEVGRLGPSDYFGEIALLMNRPRAATV 339
           + I+ QG+ GD F++I  G   V      N E V     G S  FGE+AL+   PRAATV
Sbjct: 2   ENIIQQGDEGDNFYVIDVGEVDVFV----NSELVTTISEGGS--FGELALIYGTPRAATV 163

Query: 340 VARGPLKCVKLDRPRFERVLGPCSDILKRNIQQYNSFVS 378
            A+  +K   +DR  + R+L   S I KR  + Y  F+S
Sbjct: 164 RAKSDVKLWGIDRDSYRRIL-MGSTIRKR--KMYEEFLS 271

 Score = 39.7 bits (91), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 21/72 (29%), Positives = 38/72 (52%)
 Frame = +2

Query: 109 DAASYVRKVIPKDYKTMAALAKAIEKNVLFSHLDDNERSDIFDAMFPVSFIAGETVIQQG 168
           D  SY R ++    +      + + +  +   LD  ER  + D++   +F  GET+++QG
Sbjct: 197 DRDSYRRILMGSTIRKRKMYEEFLSRVSILESLDKWERLTVADSLETCAFDDGETIVKQG 376

Query: 169 DEGDNFYVIDQG 180
             GD+FY+I +G
Sbjct: 377 AAGDDFYIILEG 412
>18204
          Length = 429

 Score =  104 bits (259), Expect = 7e-23,   Method: Compositional matrix adjust.
 Identities = 58/143 (40%), Positives = 87/143 (60%)
 Frame = -1

Query: 199 SFGELALIYGTPRAATVKAKTNVKLWGIDRDSYRRILMGSTLRKRKMYEEFLSKVSILES 258
           +FGELA++Y   R A+VKA T+VK+W +DR  ++ I+M + L++R+    FL  VS+L  
Sbjct: 429 AFGELAILYNCTRTASVKAVTDVKVWVLDRQMFQAIMMKTGLQRREENIRFLKSVSVLRD 250

Query: 259 LDKWERLTVADALEPVQFEDGQKIVVQGEPGDEFFIILEGTAAVLQRRSENEEFVEVGRL 318
           L   +   +AD LE   F +G+ I+ +G  GD FF+I +G   V Q  + +EE  E+ +L
Sbjct: 249 LPSDKLAKIADVLEIDFFHEGEFIIREGCTGDTFFLINKGEVRVTQTVAGHEEPQEIRKL 70

Query: 319 GPSDYFGEIALLMNRPRAATVVA 341
              DYFGE ALL    R A+ +A
Sbjct: 69  KRGDYFGEKALLGEDRRTASCIA 1

 Score = 30.4 bits (67), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 15/36 (41%), Positives = 22/36 (61%)
 Frame = -1

Query: 324 FGEIALLMNRPRAATVVARGPLKCVKLDRPRFERVL 359
           FGE+A+L N  R A+V A   +K   LDR  F+ ++
Sbjct: 426 FGELAILYNCTRTASVKAVTDVKVWVLDRQMFQAIM 319
>20517
          Length = 749

 Score = 49.3 bits (116), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 40/145 (27%), Positives = 63/145 (43%), Gaps = 8/145 (5%)
 Frame = +3

Query: 169 DEGDNFYVIDQGEMDV------YVNNEWATSVGEGGSFGELALIYGTPRAATVKAKTNVK 222
           D   +FY I  G + V      Y       ++ +G SFGELA+I G+ R ATV   T V+
Sbjct: 6   DPPRSFYFILSGTVVVTQFERQYSTTRTLVTLDQGMSFGELAVITGSRRQATVSTMTEVE 185

Query: 223 LWGIDRDSYRRILM--GSTLRKRKMYEEFLSKVSILESLDKWERLTVADALEPVQFEDGQ 280
           L  I    +  I M  G  +     + +FL  V  L++    +      A     F  GQ
Sbjct: 186 LLCISAKDFEDIFMAGGRKIITDPDHNKFLRSVDFLKAWPVQQLAQHPHACMFHYFNRGQ 365

Query: 281 KIVVQGEPGDEFFIILEGTAAVLQR 305
            +V      D  +I+  G+ +V+++
Sbjct: 366 VLVRDSNNSDWIYIVKSGSLSVMKK 440

 Score = 29.6 bits (65), Expect = 2.4,   Method: Compositional matrix adjust.
 Identities = 19/73 (26%), Positives = 31/73 (42%)
 Frame = +3

Query: 287 EPGDEFFIILEGTAAVLQRRSENEEFVEVGRLGPSDYFGEIALLMNRPRAATVVARGPLK 346
           +P   F+ IL GT  V Q   +      +  L     FGE+A++    R ATV     ++
Sbjct: 6   DPPRSFYFILSGTVVVTQFERQYSTTRTLVTLDQGMSFGELAVITGSRRQATVSTMTEVE 185

Query: 347 CVKLDRPRFERVL 359
            + +    FE + 
Sbjct: 186 LLCISAKDFEDIF 224
>27148
          Length = 718

 Score = 37.0 bits (84), Expect = 0.012,   Method: Compositional matrix adjust.
 Identities = 24/70 (34%), Positives = 39/70 (55%)
 Frame = -3

Query: 197 GGSFGELALIYGTPRAATVKAKTNVKLWGIDRDSYRRILMGSTLRKRKMYEEFLSKVSIL 256
           G SFGELA++  T R +TV +K N++L  +  D +  + M   L      + FL+ +S L
Sbjct: 281 GDSFGELAIMNATRRQSTVISKDNMQLLVLTDDDFVEVFMSGGLANPD--DPFLNSLSYL 108

Query: 257 ESLDKWERLT 266
           +   K E+L+
Sbjct: 107 DGWPK-EKLS 81
>18885
          Length = 838

 Score = 31.6 bits (70), Expect = 0.51,   Method: Compositional matrix adjust.
 Identities = 20/62 (32%), Positives = 29/62 (46%), Gaps = 10/62 (16%)
 Frame = -3

Query: 161 GETVIQQGDEGDNFYVIDQGEMDVYVNNE----------WATSVGEGGSFGELALIYGTP 210
           G T+ +QGD G N+Y +  G + V V++               VG G SFGE  ++ G P
Sbjct: 185 GVTLFRQGDMGTNWYTVLTGSLAVLVSDNARPKIHQDGVMLCVVGPGTSFGE-GILTGKP 9

Query: 211 RA 212
             
Sbjct: 8   HG 3

 Score = 31.2 bits (69), Expect = 0.77,   Method: Compositional matrix adjust.
 Identities = 19/65 (29%), Positives = 32/65 (49%), Gaps = 4/65 (6%)
 Frame = -3

Query: 276 FEDGQKIVVQGEPGDEFFIILEGTAAVL----QRRSENEEFVEVGRLGPSDYFGEIALLM 331
            E G  +  QG+ G  ++ +L G+ AVL     R   +++ V +  +GP   FGE  +L 
Sbjct: 194 LEKGVTLFRQGDMGTNWYTVLTGSLAVLVSDNARPKIHQDGVMLCVVGPGTSFGE-GILT 18

Query: 332 NRPRA 336
            +P  
Sbjct: 17  GKPHG 3
>19667
          Length = 442

 Score = 31.6 bits (70), Expect = 0.56,   Method: Compositional matrix adjust.
 Identities = 15/46 (32%), Positives = 24/46 (52%)
 Frame = +3

Query: 156 VSFIAGETVIQQGDEGDNFYVIDQGEMDVYVNNEWATSVGEGGSFG 201
           V F  GE +I +GD   N Y +  G ++V  + +    +G+G  FG
Sbjct: 63  VFFGPGEVLIHKGDAIRNIYYVCSGSLEVLKDEQVVAILGKGDLFG 200
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|34996495|ref|NP_062616.2| ribophorin II [Mus
musculus]
         (631 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

02552                                                                 168   2e-64
36866                                                                 136   5e-39
>02552
          Length = 1917

 Score =  168 bits (426), Expect(2) = 2e-64,   Method: Compositional matrix adjust.
 Identities = 86/187 (45%), Positives = 116/187 (62%), Gaps = 1/187 (0%)
 Frame = +1

Query: 445 QEVVFVAEPDNKNVYKFELDTSERKIEFDSASGTYTLYLIIGDATLKNPILWNVADVVIK 504
           QE++FV+E D     KF+LD      EF   SG Y++ LI+GD  ++NP  W +AD  + 
Sbjct: 463 QEIIFVSEADGTLNNKFDLDVGASAKEFGYQSGKYSVELIVGDXIIENPFSWTLADAELT 642

Query: 505 FPEE-EAPSTVLSQSLFTPKQEIQHLFREPEKRPPTVVSNTFTAXXXXXXXXXXXXWIRI 563
           FPE   A    L+Q  ++ K EI+H+FREPEKRPP  VS TFT             W++I
Sbjct: 643 FPEGGAAKGEGLNQ--YSKKPEIKHMFREPEKRPPAPVSMTFTILVLVPLLILLLLWLKI 816

Query: 564 GANVSNFTFAPSTVIFHLGHAAMLGLMYIYWTQLNMFQTLKYLAVLGTVTFLAGNRMLAQ 623
           G N++NF F+ S + FH+  A + GL Y+YWTQLNMFQTL+YL +L   TFL GNR+L+ 
Sbjct: 817 GVNIANFPFSVSAIGFHICLAGIFGLYYLYWTQLNMFQTLRYLGILAVPTFLFGNRLLSA 996

Query: 624 HAVKRTA 630
            A KR +
Sbjct: 997 IASKRKS 1017

 Score = 96.3 bits (238), Expect(2) = 2e-64,   Method: Compositional matrix adjust.
 Identities = 57/150 (38%), Positives = 85/150 (56%), Gaps = 7/150 (4%)
 Frame = +2

Query: 300 LAQAAVKLEHAKSAATRATVLQK---TPFSLVGNVFELNFKNVKLSSGYYDFSVRV---E 353
           L Q  V  + A+     A V+ K   TP +   + +ELN    K + G+Y  +V V   +
Sbjct: 8   LGQLTVTADSARHIGDGAVVISKKQFTPTAADKSQYELNLMETKPARGFYRLTVSVAPKK 187

Query: 354 GDSRYIANT-VELRVKISTEVGITNVDLSTVDKDQSIAPKTTRVTYPAKAKGTFIADSHQ 412
            D+R I  +  E+ VK++T+V + NV++   DKDQ+ A +TT++ +P KA+ +  AD HQ
Sbjct: 188 ADARLIGTSGAEVSVKVTTKVSVENVEIGVADKDQTAAARTTKLVHPNKAQNSLEADYHQ 367

Query: 413 NFALFFQLVDVNTGAELTPHQTFVRLHNQK 442
              + FQL D  TG  +T HQTFVRL N K
Sbjct: 368 KILMRFQLKDRLTGQLMTAHQTFVRLTNLK 457
>36866
          Length = 688

 Score =  136 bits (342), Expect(2) = 5e-39,   Method: Compositional matrix adjust.
 Identities = 65/156 (41%), Positives = 95/156 (60%), Gaps = 2/156 (1%)
 Frame = +3

Query: 439 HNQKTGQEVVFVAEPDNKNVYKFELDTSERKIEFDSASGTYTLYLIIGDATLKNPILWNV 498
           HN++T ++++FVAE D+   YKF++D   +   F+  +G Y +YL +GDA++ N   W +
Sbjct: 27  HNKETDKDIIFVAEQDSSKAYKFDMDVGNQGKNFNYQNGLYNIYLTVGDASISNSFEWLL 206

Query: 499 ADVVIKF--PEEEAPSTVLSQSLFTPKQEIQHLFREPEKRPPTVVSNTFTAXXXXXXXXX 556
           ADV +KF  P+ E  S+ +S     P  EI H FR P+KRPP +VS+ FT          
Sbjct: 207 ADVQLKFNQPDREIKSSPVS----GPLPEIVHQFRVPDKRPPRIVSDIFTGLCITPLVLL 374

Query: 557 XXXWIRIGANVSNFTFAPSTVIFHLGHAAMLGLMYI 592
              W ++G NVSNFT APST+ FHLG   +LGL ++
Sbjct: 375 FVFWGKLGINVSNFTLAPSTIGFHLGFGGILGLFFV 482

 Score = 43.5 bits (101), Expect(2) = 5e-39,   Method: Compositional matrix adjust.
 Identities = 19/41 (46%), Positives = 27/41 (65%)
 Frame = +2

Query: 590 MYIYWTQLNMFQTLKYLAVLGTVTFLAGNRMLAQHAVKRTA 630
           ++ +W QLNMFQTL+ L  +   TFL GNR+L +   +R A
Sbjct: 473 VFRFWLQLNMFQTLRLLIPIAIFTFLCGNRLLRRLYAQRNA 595
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|82899437|ref|XP_488540.2| PREDICTED: hypothetical
protein LOC338350 isoform 1 [Mus musculus]
         (555 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

32741                                                                 243   2e-64
16160                                                                  98   9e-21
14390                                                                  93   2e-19
08964                                                                  90   3e-18
30191                                                                  72   6e-13
03206                                                                  60   2e-09
24479                                                                  44   2e-04
36054                                                                  26   2.5  
27581                                                                  29   4.5  
21031                                                                  29   6.2  
>32741
          Length = 809

 Score =  243 bits (619), Expect = 2e-64,   Method: Compositional matrix adjust.
 Identities = 132/267 (49%), Positives = 176/267 (65%), Gaps = 9/267 (3%)
 Frame = +3

Query: 63  GQASSATAQQSGKLTESMAELAWDFATKEG------FRVFKEMPATKTLSRSYHAWAGPR 116
           GQ  S+ ++  G +TE +AE+ W  A++                   +  R Y   AG  
Sbjct: 24  GQGVSSKSEMVGVITELVAEMGWQLASESNSPQTTPSAGGAGSSDGGSQRRGYATQAG-- 197

Query: 117 SPRTPKGVRGHST--VAAASPSHEAKGGLVISPEGLSPAVRKLYEQLVQFIEQKVYPLEP 174
           S RT   V  H T  ++  + SH A G + +S E LSP V++++ ++ + I+Q V PLE 
Sbjct: 198 SSRT---VLSHLTRPMSTEASSHTA-GHMAVSVEALSPRVQEIHRRVKEIIDQHVLPLET 365

Query: 175 EL-QRHQASANRWSPSPLIEDLKEKAKAEGLWNLFLPLETDPEKKYGAGLTNVEYAHLCE 233
           EL  + + S N W+  P IE LKE AK E LWNLFLPLETDP+ KYGAGLTNVEYAH+CE
Sbjct: 366 ELAHKARDSHNPWAVHPGIEQLKEMAKREKLWNLFLPLETDPDMKYGAGLTNVEYAHICE 545

Query: 234 VMGMSLYASEIFNCSVPDMGTMEILVRYGTEEQKARWLVPLLEGRIHSCFAMTDRKVASS 293
           +MG SL A E+FNCS PD G ME+LV+YGT++Q+ +WL PLL+G+I SCF MT+  VASS
Sbjct: 546 LMGHSLIAPEVFNCSAPDTGNMEVLVKYGTQQQQQQWLTPLLDGQIRSCFGMTEPAVASS 725

Query: 294 DASNIEASIKEEDNSYVINGHKWWTSG 320
           DA+NI++SI+ + + YVINGHKWWTSG
Sbjct: 726 DATNIQSSIRRDGDHYVINGHKWWTSG 806
>16160
          Length = 1693

 Score = 98.2 bits (243), Expect = 9e-21,   Method: Compositional matrix adjust.
 Identities = 66/262 (25%), Positives = 120/262 (45%), Gaps = 4/262 (1%)
 Frame = -2

Query: 291  ASSDASNIEASIKEEDNSYVINGHKWWTSGILHPHCKLCVFMGKTDPQAPRHQQQSMLLV 350
            A SD + +     ++ + Y++NG K W +   H +    +     DP+ P  +  +  +V
Sbjct: 1692 AGSDVAGVRTKAVKKGDKYILNGQKMWITNGGHANWYFVLARTDADPKTPAGKAFTGFIV 1513

Query: 351  PMDSPGITVIRPLSVFGLEDPPGGFAEVQFKDVRVPKENIILGPGRAFEIAQGRLGRARI 410
              DSPG+  IR    + +         + F+DV VP EN++   G  F IA G   + R 
Sbjct: 1512 DGDSPGL--IRERKEWNMGQRASDTRGITFEDVEVPAENVLGQEGVGFRIAMGAFDKTRP 1339

Query: 411  HNSMRLIGYSERALALMKTRVMSRTAFGKPLVEQGTILADIARSRVEIEQARLLVLKAAH 470
              +   +G ++RAL       M R   GKP+ E   +   +A   + IE +RL  +++A 
Sbjct: 1338 PVAAGAVGLAQRALDEATRYSMERKTMGKPICEHQAVAFMLADMAIGIETSRLATMRSAW 1159

Query: 471  LMDVAGNKAAALEMAMIKMVVPSMANQVIDRAIQAFGAAGLSSDYPLAQFFGWAQTLRLG 530
             +D          +A  K +   +AN+    A+Q FG  G +S+YP+ +    A+  ++ 
Sbjct: 1158 EIDQGRRNTYYASIA--KALAADVANKCATDAVQIFGGNGFNSEYPVEKLMRDAKIYQIY 985

Query: 531  DDQLKVAKM----ELKNQSRLQ 548
            +   ++ ++    EL  ++R Q
Sbjct: 984  EGTAQIQRLIVSRELLTKARQQ 919
>14390
          Length = 1789

 Score = 93.2 bits (230), Expect = 2e-19,   Method: Compositional matrix adjust.
 Identities = 73/279 (26%), Positives = 125/279 (44%), Gaps = 4/279 (1%)
 Frame = -3

Query: 247  CSVPDMGTMEILVRYGTEEQKARWLVPLLEGRIHSCFAMTDRKVASSDASNIEASIKEED 306
            C + +     +L+  GT++QK  +L P L   +   F +++ + + SDA ++     ++ 
Sbjct: 1721 CDLQNTLINTLLMNLGTQQQKDTYL-PRLTKDMVGSFCLSEAE-SGSDAFSLRTQAVQQG 1548

Query: 307  NSYVINGHKWWTSGILHPHCKLCVFMGKTDPQAPRHQQQSMLLVPMDSPGITVIRPLSVF 366
              YVI G K W S     H  + + M    P +  ++  +  +V  D+ G+T+       
Sbjct: 1547 GDYVITGEKVWISS--AEHAGVFLVMANAKP-SDGYKGITCFIVDRDTEGLTIGNKEDKL 1377

Query: 367  GLEDPPGGFAEVQFKDVRVPKENIILGPGRAFEIAQGRLGRARIHNSMRLIGYSERALAL 426
            GL         V F  VRVP+ NI+   G+ ++ A   L   RI  + +++G +E     
Sbjct: 1376 GLRSSST--CVVNFDGVRVPESNILGEFGKGYKYAISMLNEGRIGIASQMLGLAEGCFNR 1203

Query: 427  MKTRVMSRTAFGKPLVEQGTILADIARSRVEIEQARLLVLKAAHLMDVAGNKAAAL---- 482
                 M R  FG+ + E   +   IA   ++IE AR+LV  AA        K A L    
Sbjct: 1202 TVPYTMERKQFGRRIWEFQGMQHQIATIAMQIEAARMLVYNAAR------RKEAGLPFIK 1041

Query: 483  EMAMIKMVVPSMANQVIDRAIQAFGAAGLSSDYPLAQFF 521
            E AM K+    +A     + I+  G  G + DYP+ +++
Sbjct: 1040 EAAMAKLFSAELATVTTSKCIEWMGGVGFTKDYPIEKYY 924
>08964
          Length = 2157

 Score = 89.7 bits (221), Expect = 3e-18,   Method: Compositional matrix adjust.
 Identities = 64/213 (30%), Positives = 104/213 (48%), Gaps = 1/213 (0%)
 Frame = -3

Query: 305  EDNSYVINGHK-WWTSGILHPHCKLCVFMGKTDPQAPRHQQQSMLLVPMDSPGITVIRPL 363
            + +S+V+NG K W T+G      +  V    TD Q  +H+  S  LVP+ S G++  +  
Sbjct: 1600 DGDSWVLNGTKAWITNGY---EAEATVVFATTDRQL-KHKGISAFLVPIPSEGLSRGKKE 1433

Query: 364  SVFGLEDPPGGFAEVQFKDVRVPKENIILGPGRAFEIAQGRLGRARIHNSMRLIGYSERA 423
               G++     +  + F+D R+PK+N++  PG+ F+IA   L   RI  + + +G ++ +
Sbjct: 1432 DKLGIKATSTCY--LIFEDCRIPKDNLLGQPGQGFKIAMQTLDAGRIGIAGQALGIAQAS 1259

Query: 424  LALMKTRVMSRTAFGKPLVEQGTILADIARSRVEIEQARLLVLKAAHLMDVAGNKAAALE 483
            L         R +FG P+++  TI   +A   +  + ARLL  +AA L D    K    E
Sbjct: 1258 LECAMDYAFKRQSFGMPIIKMQTIQTKLADMEMRTQSARLLTWQAAMLKDA--GKPFTKE 1085

Query: 484  MAMIKMVVPSMANQVIDRAIQAFGAAGLSSDYP 516
             AM K+     A     +AIQ  G  G  +D P
Sbjct: 1084 AAMAKLAASETATFNAHQAIQILGGMGFVTDMP 986
>30191
          Length = 575

 Score = 72.0 bits (175), Expect = 6e-13,   Method: Compositional matrix adjust.
 Identities = 43/152 (28%), Positives = 76/152 (50%)
 Frame = +3

Query: 378 VQFKDVRVPKENIILGPGRAFEIAQGRLGRARIHNSMRLIGYSERALALMKTRVMSRTAF 437
           + F+DVRVPKEN+++  G  F+IA G   + R   +   +G ++R +       + R AF
Sbjct: 18  ITFEDVRVPKENVLISEGAGFKIAMGTFDKTRPPVAAGAVGLAQRCMDEALKYALERKAF 197

Query: 438 GKPLVEQGTILADIARSRVEIEQARLLVLKAAHLMDVAGNKAAALEMAMIKMVVPSMANQ 497
           G P+ +   +   +A   + +E +RL    +A  +D     +    +A  K     MAN+
Sbjct: 198 GVPIAQHQAVQFMLADMAIGVETSRLAWRLSAWEIDQGRRNSYYASIA--KCHAADMANK 371

Query: 498 VIDRAIQAFGAAGLSSDYPLAQFFGWAQTLRL 529
           +   A+Q FG  G +SDYP+ +    A+  ++
Sbjct: 372 IASDAVQIFGGNGFNSDYPVEKLMRDAKIYQI 467
>03206
          Length = 1682

 Score = 60.1 bits (144), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 38/141 (26%), Positives = 68/141 (48%)
 Frame = -2

Query: 380  FKDVRVPKENIILGPGRAFEIAQGRLGRARIHNSMRLIGYSERALALMKTRVMSRTAFGK 439
              D RVP+ N++   G+ F IA   L   R++ +   +G ++ ++   +  +  R  FG+
Sbjct: 1588 LDDCRVPRSNLLGSEGQGFNIAMRGLNGGRVNIASCSLGAAQASVEQARDHLKVRRQFGQ 1409

Query: 440  PLVEQGTILADIARSRVEIEQARLLVLKAAHLMDVAGNKAAALEMAMIKMVVPSMANQVI 499
             L +   +   +A    ++  +RLLV +AA  +D       AL  +M K+       +V 
Sbjct: 1408 ALEDFQYLQFRLAEMSTKVVTSRLLVRQAARALDDDSPDVVAL-CSMAKLFATEECFKVC 1232

Query: 500  DRAIQAFGAAGLSSDYPLAQF 520
            + A+Q FG  G   DYP+ Q+
Sbjct: 1231 NEALQMFGGYGYLKDYPVQQY 1169
>24479
          Length = 1105

 Score = 43.5 bits (101), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 23/87 (26%), Positives = 41/87 (47%)
 Frame = +2

Query: 303 KEEDNSYVINGHKWWTSGILHPHCKLCVFMGKTDPQAPRHQQQSMLLVPMDSPGITVIRP 362
           +E+ + Y++NG K W +   H +    +     DP+ P  +  +  +V  DSPG+  IR 
Sbjct: 14  REKGDKYILNGQKMWITNGGHANWYFVLARTDVDPKTPAGKAFTGFIVDGDSPGL--IRE 187

Query: 363 LSVFGLEDPPGGFAEVQFKDVRVPKEN 389
              + +         + F+DV VP E+
Sbjct: 188 RKEWNMGQRASDTRGITFEDVEVPAEH 268
>36054
          Length = 426

 Score = 25.8 bits (55), Expect(2) = 2.5,   Method: Compositional matrix adjust.
 Identities = 10/20 (50%), Positives = 15/20 (75%)
 Frame = +2

Query: 378 VQFKDVRVPKENIILGPGRA 397
           V F+DV++P EN++ G G A
Sbjct: 2   VYFEDVKIPVENVLGGVGGA 61

 Score = 22.7 bits (47), Expect(2) = 2.5,   Method: Composition-based stats.
 Identities = 16/59 (27%), Positives = 24/59 (40%)
 Frame = +1

Query: 395 GRAFEIAQGRLGRARIHNSMRLIGYSERALALMKTRVMSRTAFGKPLVEQGTILADIAR 453
           G  F++A   L   R   +  L G  +  +        +RT FG+ +   G I   IAR
Sbjct: 52  GWGFKVAMNILNNGRFGMAAALSGTMKYCIYKAVEHAGNRTQFGRRIDSFGAIQEKIAR 228
>27581
          Length = 541

 Score = 29.3 bits (64), Expect = 4.5,   Method: Composition-based stats.
 Identities = 15/36 (41%), Positives = 22/36 (61%), Gaps = 2/36 (5%)
 Frame = -3

Query: 287 DRKVASSD-ASNIEA-SIKEEDNSYVINGHKWWTSG 320
           DRK   SD A   E  +++E D SY + G+KW++S 
Sbjct: 281 DRKTGGSDVARGTETMAVEETDGSYRLYGYKWFSSA 174
>21031
          Length = 630

 Score = 28.9 bits (63), Expect = 6.2,   Method: Compositional matrix adjust.
 Identities = 21/84 (25%), Positives = 35/84 (41%)
 Frame = -2

Query: 111 AWAGPRSPRTPKGVRGHSTVAAASPSHEAKGGLVISPEGLSPAVRKLYEQLVQFIEQKVY 170
            W G    RTP   R  S  +  SPS  ++   V      +P +   +  +V+   Q+++
Sbjct: 272 TWEGGSMTRTPVSTRCPSPASTCSPSRCSRCPTVA*FMTCTPTMS*EFALVVK-ATQRLF 96

Query: 171 PLEPELQRHQASANRWSPSPLIED 194
           P    L  H     R+  SP++ D
Sbjct: 95  PARRPLSSHYRRETRFGCSPIVPD 24
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31982373|ref|NP_032017.2| fibrillarin [Mus musculus]
         (327 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

08333                                                                 241   3e-64
>08333
          Length = 445

 Score =  241 bits (616), Expect = 3e-64,   Method: Compositional matrix adjust.
 Identities = 110/137 (80%), Positives = 125/137 (91%)
 Frame = -3

Query: 91  NVMVEPHRHEGVFICRGKEDALVTKNLVPGESVYGEKRVSISEGDDKIEYRAWNPFRSKL 150
            V +EPHRHEG+FI RGKEDALVT+N VPG  VYGEKR+S+    +KIEYR WNPFRSKL
Sbjct: 413 TVTIEPHRHEGIFIARGKEDALVTRNFVPGSEVYGEKRISVETNGEKIEYRVWNPFRSKL 234

Query: 151 AAAILGGVDQIHIKPGAKVLYLGAASGTTVSHVSDIVGPDGLVYAVEFSHRSGRDLINLA 210
           AAA+LGGV++IH+ PG+KVLYLGAASGTTVSHVSD+VGP+GLVYAVEFSHRSGRDLIN+A
Sbjct: 233 AAAVLGGVEKIHMPPGSKVLYLGAASGTTVSHVSDVVGPEGLVYAVEFSHRSGRDLINVA 54

Query: 211 KKRTNIIPVIEDARHPH 227
           KKRTNIIP+IEDARHPH
Sbjct: 53  KKRTNIIPIIEDARHPH 3
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6679545|ref|NP_033000.1| protein tyrosine phosphatase
4a2 [Mus musculus]
         (167 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

14057                                                                 239   3e-64
25697                                                                 218   1e-57
30741                                                                  35   0.011
19962                                                                  34   0.031
29613                                                                  32   0.096
15655                                                                  28   1.3  
11098                                                                  27   4.8  
01924                                                                  27   5.9  
>14057
          Length = 1377

 Score =  239 bits (611), Expect = 3e-64,   Method: Compositional matrix adjust.
 Identities = 109/161 (67%), Positives = 133/161 (82%)
 Frame = +2

Query: 3   RPAPVEISYENMRFLITHNPTNATLNKFTEELKKYGVTTLVRVCDATYDKAPVEKEGIHV 62
           RP P EI ++NMRFLIT  PT++T++K+ EEL+K+G   +VRVCD TY +  ++K GI V
Sbjct: 674 RPEPAEIEFKNMRFLITDRPTDSTIDKYIEELQKHGAKHVVRVCDPTYSREVLQKAGIDV 853

Query: 63  LDWPFDDGAPPPNQIVDDWLNLLKTKFREEPGCCVAVHCVAGLGRAPVLVALALIECGMK 122
           LDW FDDG+PPPN++V +W NLLK +F+EEPGCCVAVHCVAGLGRAPVLVA+AL+E GMK
Sbjct: 854 LDWQFDDGSPPPNEVVGNWFNLLKARFKEEPGCCVAVHCVAGLGRAPVLVAIALMEAGMK 1033

Query: 123 YEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFRDTNGH 163
           YEDAV+ IRQKRRGA NSKQL YL+ YRPK RLR  + NGH
Sbjct: 1034YEDAVELIRQKRRGAINSKQLSYLQHYRPKSRLR-HNRNGH 1153
>25697
          Length = 470

 Score =  218 bits (555), Expect = 1e-57,   Method: Compositional matrix adjust.
 Identities = 100/150 (66%), Positives = 122/150 (81%), Gaps = 1/150 (0%)
 Frame = +1

Query: 15  RFLITHNPTNATLNKFTEELKKYGVTTLVRVCDATYDKAPVEKEGIHVLDWPFDDGAPPP 74
           RFLIT  PT++TL+KF EEL+K+G   +VRVCD TY K  +E EGI V+DW FDDG+PPP
Sbjct: 1   RFLITDRPTDSTLDKFIEELQKHGARHVVRVCDPTYSKEKLETEGIDVMDWQFDDGSPPP 180

Query: 75  NQIVDDWLNLLKTKFREEPGCCVAVHCVAGLGRAPVLVALALIECGMKYEDAVQFIRQKR 134
             +V +W NLLK  F+++PGCCVAVHCVAGLGRAPVLVA+AL+E GMKYEDAV+ IR+KR
Sbjct: 181 KDVVGNWFNLLKASFKDDPGCCVAVHCVAGLGRAPVLVAIALMEAGMKYEDAVELIRRKR 360

Query: 135 RGAFNSKQLLYLEKYRPKMRLRFR-DTNGH 163
           RGA NSKQL YL+ YRP+ RLR + + NGH
Sbjct: 361 RGAINSKQLSYLQHYRPRSRLRSKANRNGH 450
>30741
          Length = 506

 Score = 35.4 bits (80), Expect = 0.011,   Method: Compositional matrix adjust.
 Identities = 18/72 (25%), Positives = 31/72 (43%)
 Frame = -3

Query: 43  VRVCDATYDKAPVEKEGIHVLDWPFDDGAPPPNQIVDDWLNLLKTKFREEPGCCVAVHCV 102
           +RV D          +  H + WP D G P    ++ ++++ ++            VHC 
Sbjct: 459 IRVIDIKLGSQSRMIKHFHFMRWP-DHGCPERTSMLLNFVSSVRAHMPHTGAGPTLVHCS 283

Query: 103 AGLGRAPVLVAL 114
           AG+GR    +AL
Sbjct: 282 AGVGRTGTFIAL 247
>19962
          Length = 410

 Score = 33.9 bits (76), Expect = 0.031,   Method: Compositional matrix adjust.
 Identities = 20/62 (32%), Positives = 30/62 (48%)
 Frame = +1

Query: 56  EKEGIHVLDWPFDDGAPPPNQIVDDWLNLLKTKFREEPGCCVAVHCVAGLGRAPVLVALA 115
           E   +H   WP D G P P  +V  W  +  T+   +    + VHC AG+GR    +AL 
Sbjct: 127 EVHLLHFTAWP-DHGVPCPVTLVRFWSYV--TRQPAQLSGPLLVHCSAGIGRTGTYIALD 297

Query: 116 LI 117
           ++
Sbjct: 298 ML 303
>29613
          Length = 425

 Score = 32.3 bits (72), Expect = 0.096,   Method: Compositional matrix adjust.
 Identities = 18/55 (32%), Positives = 27/55 (49%), Gaps = 2/55 (3%)
 Frame = -2

Query: 79  DDWLNLLKTKFREEPGCC--VAVHCVAGLGRAPVLVALALIECGMKYEDAVQFIR 131
           DD L+ + +   E  GC   + VHC AG+GR    +AL  +         +QF+R
Sbjct: 241 DDVLDFISSVRLESRGCQGPMVVHCSAGVGRTGTFIALDFL---------MQFVR 104
>15655
          Length = 467

 Score = 28.5 bits (62), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 24/100 (24%), Positives = 39/100 (39%), Gaps = 11/100 (11%)
 Frame = +1

Query: 28  NKFTEELKKYGVTTLVRVCDATYDKAPVEKEGIHVLDWPFDDGAPPPNQIVDDWLNL--- 84
           NK  +  K Y  T L+     T +   V    +  + WP D G PP    +D   ++   
Sbjct: 88  NKSVQTYKNYVETKLILRNTETDEWREVTH--LQFISWP-DYGIPPATGFLDFLFHVREV 258

Query: 85  -------LKTKFREEP-GCCVAVHCVAGLGRAPVLVALAL 116
                  +   +   P G  + VHC AG+GR    + + +
Sbjct: 259 QASATTKMGASWAGHPLGPPIVVHCSAGIGRTGTFITIDI 378
>11098
          Length = 1151

 Score = 26.6 bits (57), Expect = 4.8,   Method: Compositional matrix adjust.
 Identities = 17/62 (27%), Positives = 34/62 (54%), Gaps = 3/62 (4%)
 Frame = -3

Query: 28  NKFTEELKKYGVTTLVRVCDATYDKA--PVEKEGIHVLDWPFDDGAPPPNQI-VDDWLNL 84
           N+F   +K + V  ++  C  T+DK     EK+ ++V  +   +G+P  +   VD+ ++L
Sbjct: 948 NEFVPFIKNFDVDEIMNFCTFTFDKQLFGTEKDVLYVCTYVPPEGSPFYSHFGVDNGISL 769

Query: 85  LK 86
           L+
Sbjct: 768 LE 763
>01924
          Length = 1183

 Score = 26.6 bits (57), Expect = 5.9,   Method: Compositional matrix adjust.
 Identities = 15/63 (23%), Positives = 29/63 (46%), Gaps = 3/63 (4%)
 Frame = -3

Query: 94  GCCVAVHCVAGLGRAPVLVALALIECGM---KYEDAVQFIRQKRRGAFNSKQLLYLEKYR 150
           GC + +  +   GR PV+  + L++CG+     +  V  I  + R     +QL +  +  
Sbjct: 221 GCMIGI--MVQFGRQPVITLITLVDCGLPAVSVQHGVVIITARCRRVQRGRQLRHFFRQT 48

Query: 151 PKM 153
           P +
Sbjct: 47  PSI 39
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|154090967|ref|NP_536696.4| SLIT-ROBO Rho GTPase
activating protein 3 [Mus musculus]
         (1099 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

17558                                                                 242   5e-64
19079                                                                  84   4e-16
17428                                                                  66   9e-11
20879                                                                  61   3e-09
12558                                                                  60   6e-09
30765                                                                  59   1e-08
12324                                                                  42   0.002
30740                                                                  39   0.011
19361                                                                  37   0.054
16716                                                                  36   0.11 
20131                                                                  35   0.16 
13664                                                                  33   0.48 
29419                                                                  31   3.3  
26032                                                                  30   5.0  
32409                                                                  30   7.2  
>17558
          Length = 671

 Score =  242 bits (618), Expect = 5e-64,   Method: Compositional matrix adjust.
 Identities = 119/208 (57%), Positives = 147/208 (70%)
 Frame = +3

Query: 502 KLFNGSMEAFIKDSGQAIPLVVESCIRFINLYGLQQQGIFRVPGSQVEVNDIKNSFERGE 561
           KLF GS+E +I+ +G+ IPL+++ CIR INLYGL  QG+FRV G+QVE+N  KN FE G+
Sbjct: 51  KLFGGSLEEYIEATGEEIPLIIKGCIRVINLYGLHHQGVFRVSGAQVEINHFKNVFESGD 230

Query: 562 DPLVDDQNERDINSVAGVLKLYFRGLENPLFPKERFQDLISTIKLENPADRVHPIQQILI 621
           D LVD  +  D+NS+AGVLKLYFR L  PLFP   F  L+   +  +   R+  I+ +L 
Sbjct: 231 DALVDVVDASDMNSIAGVLKLYFRELREPLFPLHLFDALVECTRENDVHRRLERIKDLLA 410

Query: 622 TLPRVVIVVMRYLFAFLNHLSQYSDENMMDPYNLAICFGPTLMHIPDGQDPVSCQAHVNE 681
           TLPR V VVMRYLFAFLNHLS+YSDENMMDPYNLAICFGPTL+ IP  +D V        
Sbjct: 411 TLPRSVFVVMRYLFAFLNHLSEYSDENMMDPYNLAICFGPTLLPIPPDRDQVVLPGLRQR 590

Query: 682 VIKTIIIHHEAIFPSPRELEGPVYEKCM 709
           +IKTII+H E IFP+     G  YEKC+
Sbjct: 591 IIKTIIVHQEEIFPND---GGETYEKCI 665
>19079
          Length = 436

 Score = 83.6 bits (205), Expect = 4e-16,   Method: Composition-based stats.
 Identities = 41/87 (47%), Positives = 56/87 (64%)
 Frame = -1

Query: 547 QVEVNDIKNSFERGEDPLVDDQNERDINSVAGVLKLYFRGLENPLFPKERFQDLISTIKL 606
           QV++N+ K  FE GED LVD  +  ++NSVAGVLKLYFR L  PLFP   F  L+   + 
Sbjct: 379 QVDINNFKAVFESGEDALVDVTDASEMNSVAGVLKLYFRELREPLFPLHLFDALVECTRE 200

Query: 607 ENPADRVHPIQQILITLPRVVIVVMRY 633
            +   R+  I+ +L +LPR + VVMR+
Sbjct: 199 ISVQRRLDSIRDLLASLPRAIFVVMRW 119

 Score = 34.3 bits (77), Expect = 0.25,   Method: Composition-based stats.
 Identities = 14/33 (42%), Positives = 20/33 (60%)
 Frame = -2

Query: 528 RFINLYGLQQQGIFRVPGSQVEVNDIKNSFERG 560
           R +NLYGL  QG+FRV G++      + S  +G
Sbjct: 435 RVVNLYGLHHQGVFRVSGARWTSTTSRPSLSQG 337
>17428
          Length = 623

 Score = 65.9 bits (159), Expect = 9e-11,   Method: Compositional matrix adjust.
 Identities = 54/191 (28%), Positives = 84/191 (43%), Gaps = 18/191 (9%)
 Frame = +1

Query: 538 QGIFRVPGSQVEVNDIKNSFERGEDPLVD-DQNERDINSVAGVLKLYFRGLENPLFPKER 596
           +G+FR      +   +K  F+     LVD ++   D N+VAGV+K Y R L  P+   + 
Sbjct: 1   EGLFRFSRISFKDEKLKACFDAR---LVDMEEFSNDPNTVAGVMKQYLRELPEPMLTFDL 171

Query: 597 FQDLISTIKLENPADRVHPIQQILITLPRVVIVVMRYLFAFLNHLSQYSDENMMDPYNLA 656
           + D +   +L +   +   +  ++  LP       RYL  FL  L++ S  N M P NLA
Sbjct: 172 YPDFMRAAQLGH-DQKCQSLYTLVNRLPPSNFNNFRYLIKFLALLAEKSHVNKMTPSNLA 348

Query: 657 ICFGPTLMHIPDGQDP-VSCQAHVNEVIKTIIIHHEAIFPS----------------PRE 699
           I  GP L+       P +   + V+ +I+T ++H E  FP                 PR 
Sbjct: 349 IVMGPNLLWARGENTPNMMTASTVSSIIETFVLHAEYFFPGELXPDIFDI*LPFHLRPRS 528

Query: 700 LEGPVYEKCMA 710
           L   V+  C A
Sbjct: 529 LHSVVFGFCWA 561
>20879
          Length = 1019

 Score = 60.8 bits (146), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 34/90 (37%), Positives = 48/90 (53%)
 Frame = -2

Query: 502 KLFNGSMEAFIKDSGQAIPLVVESCIRFINLYGLQQQGIFRVPGSQVEVNDIKNSFERGE 561
           KL  G +  F       IP +V +C   I   GL + GI+RVPGS  +  D+K  F +G+
Sbjct: 616 KLTEGILADFAPTQRPMIPRLVVNCANEIERRGLSEVGIYRVPGSDRDSKDLKEKFLKGK 437

Query: 562 DPLVDDQNERDINSVAGVLKLYFRGLENPL 591
            P  +  N  DI++V G LK + R L+ PL
Sbjct: 436 SP--NLSNIIDIHTVCGCLKDFLRNLKEPL 353
>12558
          Length = 720

 Score = 59.7 bits (143), Expect = 6e-09,   Method: Compositional matrix adjust.
 Identities = 36/128 (28%), Positives = 66/128 (51%), Gaps = 2/128 (1%)
 Frame = -1

Query: 539 GIFRVPGSQVEVNDIKNSFERGEDPLVDD--QNERDINSVAGVLKLYFRGLENPLFPKER 596
           G++R+ G    +  ++ +F+  + P + D  Q  +DI+S++ +LK+YFR L NPL   + 
Sbjct: 711 GLYRLSGVTSNIQKLRVAFDEDQAPELSDNVQYLQDIHSISSLLKMYFRELPNPLLTYQL 532

Query: 597 FQDLISTIKLENPADRVHPIQQILITLPRVVIVVMRYLFAFLNHLSQYSDENMMDPYNLA 656
           +      +K E+  +R+  I  ++  LP      + YL   L  ++ Y  +  M   NLA
Sbjct: 531 YTQFADAVKDED--NRLLRIHDVVQQLPPPHYRTLEYLVRHLACVASYGLQTGMHSKNLA 358

Query: 657 ICFGPTLM 664
           I + P L+
Sbjct: 357 IVWAPNLL 334
>30765
          Length = 635

 Score = 58.9 bits (141), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 31/98 (31%), Positives = 53/98 (54%), Gaps = 1/98 (1%)
 Frame = +2

Query: 497 SVYSHKLFNGSMEAFIKDSGQAIPLVVESCIRFINLYGLQQQGIFRVPGSQVEVNDIKNS 556
            +    +F  +++A        +P  V  CI  +   GL Q G++RV G+  E+  ++  
Sbjct: 257 GIIKDAVFGSTLQAQCDKDKAPVPNFVLECIAAVEKKGLDQDGLYRVSGNLAEIQRLRYV 436

Query: 557 FERGED-PLVDDQNERDINSVAGVLKLYFRGLENPLFP 593
            ++ +D  L +DQ   DI+++ G LKL+FR L+ PLFP
Sbjct: 437 VDKDDDHNLTEDQ--WDIHTLTGALKLFFRELKEPLFP 544
>12324
          Length = 946

 Score = 41.6 bits (96), Expect = 0.002,   Method: Composition-based stats.
 Identities = 19/65 (29%), Positives = 34/65 (52%)
 Frame = +3

Query: 734 GTEPHTSDEEVEQIEAIAKFDYVGRSPRELSFKKGASLLLYHRASEDWWEGRHNGVDGLI 793
           G + +     +E++ AI  +DY      EL+F + + + +  +  + WWEG  +GV GL 
Sbjct: 657 GPDEYMPATYIEKVVAI--YDYEAEKDDELTFSENSVIYVIRKNDDGWWEGVMDGVTGLF 830

Query: 794 PHQYI 798
           P  Y+
Sbjct: 831 PSNYV 845
>30740
          Length = 488

 Score = 38.9 bits (89), Expect = 0.011,   Method: Compositional matrix adjust.
 Identities = 15/36 (41%), Positives = 21/36 (58%)
 Frame = +2

Query: 750 IAKFDYVGRSPRELSFKKGASLLLYHRASEDWWEGR 785
           + K+D+ GR P +L F KG  L L  +  E+WW  R
Sbjct: 194 MGKYDFSGRDPEDLPFSKGDILELISKDEEEWWTAR 301
>19361
          Length = 685

 Score = 36.6 bits (83), Expect = 0.054,   Method: Compositional matrix adjust.
 Identities = 15/48 (31%), Positives = 28/48 (58%)
 Frame = -1

Query: 499 YSHKLFNGSMEAFIKDSGQAIPLVVESCIRFINLYGLQQQGIFRVPGS 546
           Y  +L+   +    K + Q +P+VVE CI+ I   G++ +G++R+  S
Sbjct: 151 YVKRLYGVDLTTVTKANKQILPIVVEXCIKEIEKRGVEPEGLYRLAXS 8
>16716
          Length = 934

 Score = 35.8 bits (81), Expect = 0.11,   Method: Compositional matrix adjust.
 Identities = 17/53 (32%), Positives = 25/53 (47%)
 Frame = -1

Query: 749 AIAKFDYVGRSPRELSFKKGASLLLYHRASEDWWEGRHNGVDGLIPHQYIVVQ 801
           AIA +DY      EL+F     +       + WW G  +G +GL P  Y+ +Q
Sbjct: 463 AIALYDYQAADDDELTFDPDDVITDIEMIDDGWWRGSCHGKNGLFPANYVELQ 305
>20131
          Length = 574

 Score = 35.0 bits (79), Expect = 0.16,   Method: Compositional matrix adjust.
 Identities = 15/49 (30%), Positives = 25/49 (51%)
 Frame = -2

Query: 750 IAKFDYVGRSPRELSFKKGASLLLYHRASEDWWEGRHNGVDGLIPHQYI 798
           +A + YV     +L+F +G  ++L  +  EDWW G      G+ P  Y+
Sbjct: 471 VAMYSYVSGETADLTFNEG-DMILVTKKDEDWWTGTLGEKTGMFPSTYV 328
>13664
          Length = 507

 Score = 33.5 bits (75), Expect = 0.48,   Method: Compositional matrix adjust.
 Identities = 13/37 (35%), Positives = 21/37 (56%)
 Frame = +2

Query: 748 EAIAKFDYVGRSPRELSFKKGASLLLYHRASEDWWEG 784
           + +A +DY  +   EL+   G  ++L H+ SE WW G
Sbjct: 368 KVVALYDYKAQRSDELTILSGDVIMLLHKDSESWWMG 478
>29419
          Length = 511

 Score = 30.8 bits (68), Expect = 3.3,   Method: Composition-based stats.
 Identities = 25/71 (35%), Positives = 29/71 (40%), Gaps = 1/71 (1%)
 Frame = -3

Query: 862 AIPRRRSGGDTHSPPRGLGPSIDTPPRAAACPSSP-HKIPLSRGRIESPEKRRMATFGSA 920
           A   R  G    SPP GL PS       +AC +SP H  P  R R  SP     A    A
Sbjct: 395 AAASRCVGSRPGSPPAGLPPS*VPLAGLSACLTSPSHPSPAPRPRTRSPCAPLYAGCRWA 216

Query: 921 GSINYPDKKAL 931
            S  +  K+ L
Sbjct: 215 ASWTWKSKRVL 183
>26032
          Length = 465

 Score = 30.0 bits (66), Expect = 5.0,   Method: Composition-based stats.
 Identities = 15/49 (30%), Positives = 23/49 (46%)
 Frame = +2

Query: 754 DYVGRSPRELSFKKGASLLLYHRASEDWWEGRHNGVDGLIPHQYIVVQD 802
           D+      EL F+K   + L  +  E  W G  NG+ G  P +++ V D
Sbjct: 29  DFERHDDDELGFRKNDIITLISQKDEHCWIGELNGLRGWFPAKFVEVLD 175
>32409
          Length = 588

 Score = 29.6 bits (65), Expect = 7.2,   Method: Compositional matrix adjust.
 Identities = 28/113 (24%), Positives = 48/113 (42%), Gaps = 14/113 (12%)
 Frame = +3

Query: 887 PRAAACPSSPHKIPLSRGRIESP-----------EKRRMATFGSAGSINYPDKKALTEGL 935
           P+    PS PH+   SR + +SP           E ++     SAG+     + A  +G 
Sbjct: 195 PQKTQTPSPPHQKSPSRKQQQSPTKQLETKNPETESQKKQKGNSAGTDKASIRTATNKGA 374

Query: 936 SMRSTCGS---TRHSSLGDHKSLEAEALAEDIEKTMSTALHELRELERQNTVK 985
             R+T      T  S +    + E     ++ E+T +T  HE ++ E+  TV+
Sbjct: 375 GFRTTQTKQEETEQSEIAQQTTEEPHITQQESEQTQTT--HEEQKTEQSQTVQ 527
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|33859482|ref|NP_031933.1| eukaryotic translation
elongation factor 2 [Mus musculus]
         (858 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

15617                                                                 231   7e-64
20758                                                                 128   7e-54
26111                                                                  98   1e-29
13945                                                                  76   9e-24
08198                                                                  82   1e-15
05177                                                                  54   2e-07
18903                                                                  46   5e-05
00709                                                                  42   0.001
32306                                                                  37   0.030
13184                                                                  34   0.21 
29559                                                                  30   2.9  
>15617
          Length = 595

 Score =  231 bits (588), Expect(2) = 7e-64,   Method: Compositional matrix adjust.
 Identities = 116/148 (78%), Positives = 127/148 (85%), Gaps = 2/148 (1%)
 Frame = -3

Query: 15  KKANIRNMSVIAHVDHGKSTLTDSLVCKAGIIASARAGETRFTDTRKDEQERCITIKSTA 74
           ++ NIRNMSVIAHVDHGKSTLTDSLV KAGIIASA+AGETRFTDTRKDEQERCITIKSTA
Sbjct: 446 QQKNIRNMSVIAHVDHGKSTLTDSLVSKAGIIASAKAGETRFTDTRKDEQERCITIKSTA 267

Query: 75  ISLFYELSENDLNFIKQ--SKDGSGFLINLIDSPGHVDFSSEVTAALRVTDGALXXXXXX 132
           ISL+YEL ++D+ +IKQ   +D + FLINLIDSPGHVDFSSEVTAALRVTDGAL      
Sbjct: 266 ISLYYELKKDDMKYIKQDYDQDNNAFLINLIDSPGHVDFSSEVTAALRVTDGALVVVDCV 87

Query: 133 XXXXXQTETVLRQAIAERIKPVLMMNKM 160
                QTETVLRQAI ERI+PVLMMNKM
Sbjct: 86  SGVCVQTETVLRQAIGERIRPVLMMNKM 3

 Score = 32.7 bits (73), Expect(2) = 7e-64,   Method: Composition-based stats.
 Identities = 14/16 (87%), Positives = 14/16 (87%)
 Frame = -1

Query: 1   MVNFTVDQIRAIMDKK 16
           MVNFTVDQIR IMD K
Sbjct: 487 MVNFTVDQIREIMDNK 440
>20758
          Length = 530

 Score =  128 bits (322), Expect(2) = 7e-54,   Method: Compositional matrix adjust.
 Identities = 59/107 (55%), Positives = 72/107 (67%)
 Frame = +2

Query: 752 PEQVVGGIYGVLNRKRGHVFEESQVAGTPMFVVKAYLPVNESFGFTADLRSNTGGQAFPQ 811
           P+  +GGIY  L ++RG V  E  V GTP+ + KAYLPV ESFGFT  LR +T G+AFPQ
Sbjct: 188 PDDAMGGIYQTLTQRRGIVIGEEPVPGTPLVICKAYLPVAESFGFTQHLRQSTSGRAFPQ 367

Query: 812 CVFDHWQILPGDPFDNSSRPSQVVAETRKRKGLKEGIPALDNFLDKL 858
           CVFDHW  +   P +  ++   V    RKRKGLK G+P LDNFLDKL
Sbjct: 368 CVFDHWDTINTSPLEEGTKGHSVCEGIRKRKGLKPGVPGLDNFLDKL 508

 Score =  101 bits (252), Expect(2) = 7e-54,   Method: Composition-based stats.
 Identities = 41/63 (65%), Positives = 52/63 (82%)
 Frame = +3

Query: 690 GALCEENMRGVRFDVHDVTLHADAIHRGGGQIIPTARRCLYASVLTAQPRLMEPIYLVEI 749
           G + EENMRG++F++ DV+LH DAIHRGGGQIIPTARR  YA+ L+A+PR  EP++L EI
Sbjct: 3   GVMTEENMRGIKFNIQDVSLHTDAIHRGGGQIIPTARRVFYAACLSAEPRFQEPVFLCEI 182

Query: 750 QCP 752
           Q P
Sbjct: 183 QTP 191
>26111
          Length = 413

 Score = 98.2 bits (243), Expect(2) = 1e-29,   Method: Composition-based stats.
 Identities = 41/76 (53%), Positives = 57/76 (75%)
 Frame = -3

Query: 612 GLAEDIDKGEVSARQELKARARYLAEKYEWDVAEARKIWCFGPDGTGPNILTDITKGVQY 671
           GLAE ID+G ++A Q +K R + L   + +D+  A KIWCFGP+G+GPN+L D T  VQ+
Sbjct: 228 GLAEAIDEGTIAATQNVKERGKMLNASFNFDLNLAHKIWCFGPEGSGPNLLVDSTFAVQH 49

Query: 672 LNEIKDSVVAGFQWAT 687
           L +I+D+VVAGFQWA+
Sbjct: 48  LQDIRDTVVAGFQWAS 1

 Score = 51.2 bits (121), Expect(2) = 1e-29,   Method: Composition-based stats.
 Identities = 27/62 (43%), Positives = 32/62 (51%)
 Frame = -2

Query: 551 ELHLEICLKDLEEDHACIPIKKSDPVVSYRETVSEESNVLCLSKSPNKHNRLYMKARPFP 610
           ELHLEICLKDLE  HA +P +                      KS NKHNRL+M A+P  
Sbjct: 412 ELHLEICLKDLETVHAGVPSRNQTRWCGIVRR*QRPLVRCVWPKSNNKHNRLFMTAQPLA 233

Query: 611 DG 612
           +G
Sbjct: 232 EG 227
>13945
          Length = 664

 Score = 75.9 bits (185), Expect(2) = 9e-24,   Method: Composition-based stats.
 Identities = 31/36 (86%), Positives = 35/36 (97%)
 Frame = -3

Query: 384 GIKSCDPKGPLMMYISKMVPTSDKGRFYAFGRVFSG 419
           GIK+CDPKG L+MY+SKMVPTSDKGRF+AFGRVFSG
Sbjct: 614 GIKTCDPKGELVMYVSKMVPTSDKGRFFAFGRVFSG 507

 Score = 53.5 bits (127), Expect(2) = 9e-24,   Method: Compositional matrix adjust.
 Identities = 24/33 (72%), Positives = 27/33 (81%)
 Frame = -1

Query: 419 GVVSTGLKVRIMGPNYTPGKKEDLYLKPIQRTI 451
           G V+TG KVRIMGPN+ PGKKEDLY K IQR +
Sbjct: 508 GTVATGQKVRIMGPNFIPGKKEDLYEKSIQRLV 410
>08198
          Length = 2555

 Score = 82.0 bits (201), Expect = 1e-15,   Method: Compositional matrix adjust.
 Identities = 45/127 (35%), Positives = 62/127 (48%), Gaps = 16/127 (12%)
 Frame = -1

Query: 735  TAQPRLMEPIYLVEIQCPEQVVGGIYGVLNRKRGHVFEESQVAGTPMFVVKAYLPVNESF 794
            T   RLM  +Y   IQ    ++G +Y V+ ++ G V +E    GT +F V    PV ESF
Sbjct: 2183 TMPQRLMVAMYRCVIQADMDILGKLYAVIGKRNGRVIQEQLREGTQIFNVVTEFPVAESF 2004

Query: 795  GFTADLRSNTGGQAFPQCVFDHWQILPGDPF----------------DNSSRPSQVVAET 838
            G   ++R  T G A PQ  F HWQ+L  DPF                D+ ++    + E 
Sbjct: 2003 GLAEEMRKRTSGLASPQLRFSHWQVLDIDPFWVPSTEEEYLHYGEKADSDNQARTYMNEV 1824

Query: 839  RKRKGLK 845
            R+RKGLK
Sbjct: 1823 RRRKGLK 1803
>05177
          Length = 594

 Score = 54.3 bits (129), Expect = 2e-07,   Method: Composition-based stats.
 Identities = 32/95 (33%), Positives = 54/95 (56%), Gaps = 1/95 (1%)
 Frame = -3

Query: 725 ARRCLYASVLTAQPRLMEPIYLVEIQCPEQVVGGIYGVLNRKRGHV-FEESQVAGTPMFV 783
           A +CL  ++  A P+L+EP+  +EI   E  + G+ G L+++R HV F  S+     + +
Sbjct: 565 AVQCLTQAIKQAGPQLLEPLMKLEISTDEDKLHGVLGDLSQRRSHVNFITSR---HDIKL 395

Query: 784 VKAYLPVNESFGFTADLRSNTGGQAFPQCVFDHWQ 818
           V+A  P++E  G++ DLR+ T G A       H+Q
Sbjct: 394 VEALTPLSELVGYSTDLRTITSGTATVSMELSHYQ 290
>18903
          Length = 814

 Score = 46.2 bits (108), Expect = 5e-05,   Method: Composition-based stats.
 Identities = 24/55 (43%), Positives = 30/55 (54%)
 Frame = +2

Query: 108 HVDFSSEVTAALRVTDGALXXXXXXXXXXXQTETVLRQAIAERIKPVLMMNKMDR 162
           HVDF+ EV  ALRV DG +           QT TV RQA    I  ++ +NKMD+
Sbjct: 2   HVDFTVEVERALRVLDGTVTVLDASAGVEAQTLTVWRQAANYSIPSLVYLNKMDK 166
>00709
          Length = 1076

 Score = 42.0 bits (97), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 37/122 (30%), Positives = 53/122 (43%), Gaps = 16/122 (13%)
 Frame = -2

Query: 21  NMSVIAHVDHGKSTLTDSLVCKAGII----------ASARAGETRFT-----DTRKDEQE 65
           N+ VI HVD GKST T  L+ K G I           +   G+  F      D  K E+E
Sbjct: 883 NIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAQEMGKGSFKYAWVLDKLKAERE 704

Query: 66  RCITIKSTAISLF-YELSENDLNFIKQSKDGSGFLINLIDSPGHVDFSSEVTAALRVTDG 124
           R ITI    I+L+ +E ++              + + +ID+PGH DF   +       D 
Sbjct: 703 RGITID---IALWKFETTK--------------YYVTIIDAPGHRDFIKNMITGTSQADC 575

Query: 125 AL 126
           A+
Sbjct: 574 AV 569
>32306
          Length = 441

 Score = 37.0 bits (84), Expect = 0.030,   Method: Compositional matrix adjust.
 Identities = 19/57 (33%), Positives = 32/57 (56%)
 Frame = +1

Query: 551 ELHLEICLKDLEEDHACIPIKKSDPVVSYRETVSEESNVLCLSKSPNKHNRLYMKAR 607
           E+HL+ C+ DL + +A I +  S P+V +RETV     V  ++++    N +   AR
Sbjct: 7   EVHLQRCIDDLTQRYANIEVNVSKPIVPFRETVIPRPKVDRVNEAIQDQNTVLASAR 177
>13184
          Length = 847

 Score = 34.3 bits (77), Expect = 0.21,   Method: Compositional matrix adjust.
 Identities = 19/68 (27%), Positives = 37/68 (54%), Gaps = 1/68 (1%)
 Frame = +1

Query: 742 EPIYLVEIQCPEQVVGGIYGVLNRKRGHVFEESQVAGTPMFVVKAYLPVNESF-GFTADL 800
           EP+    + CP+Q +GG+  +   +RG + ++  +  + + ++  + P+NE    F  DL
Sbjct: 1   EPMVKGTVICPDQYLGGVTSLCLDRRGVIEDQLNIDNSHIMLIIKF-PLNEILVDFFDDL 177

Query: 801 RSNTGGQA 808
           +S T G A
Sbjct: 178 KSITSGYA 201
>29559
          Length = 702

 Score = 30.4 bits (67), Expect = 2.9,   Method: Composition-based stats.
 Identities = 11/23 (47%), Positives = 15/23 (65%)
 Frame = +1

Query: 343 WLPAGDALLQMITIHLPSPVTAQ 365
           WLP G     ++T HLPSP+T +
Sbjct: 385 WLPTGHCTAWILTSHLPSPLTPK 453
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|21313156|ref|NP_080202.1| DnaJ (Hsp40) homolog,
subfamily B, member 4 [Mus musculus]
         (337 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

10680                                                                 240   8e-64
20488                                                                 205   2e-53
14550                                                                  91   6e-19
26984                                                                  77   8e-15
12040                                                                  75   3e-14
07620                                                                  49   3e-13
02324                                                                  70   9e-13
13998                                                                  70   1e-12
22505                                                                  42   1e-07
02088                                                                  52   5e-07
13422                                                                  44   8e-05
15360                                                                  42   4e-04
20155                                                                  29   2.4  
33510                                                                  28   3.7  
18150                                                                  28   4.1  
38321                                                                  28   4.6  
05107                                                                  28   6.0  
>10680
          Length = 1093

 Score =  240 bits (612), Expect = 8e-64,   Method: Compositional matrix adjust.
 Identities = 122/280 (43%), Positives = 172/280 (61%), Gaps = 2/280 (0%)
 Frame = -3

Query: 57   DPKKREIYDQFXXXXXXXXXXXXXXXXXTFR--YTFHGDPHATFAAFFGGSNPFEIFFGR 114
            D +KR +YDQF                  +   YTFHG+P   F  FFGG NPF+ F+ R
Sbjct: 1091 DQRKRAVYDQFGEEGLKNGVPTGSGETGAWTQGYTFHGNPDKVFRDFFGGDNPFQEFYDR 912

Query: 115  RMGGGRDSEEMEIDGDPFSAFGFSMNGYPRDRNSVGPSRLKQDPPIIHELKVSLEEIYSG 174
                        +DGD    FG             G    KQDPPI  +L ++LEE++ G
Sbjct: 911  ------------VDGDLSMGFG----------GLHGRGSKKQDPPIERDLFLALEEVFHG 798

Query: 175  CTKRMKISRKRLNPDGRSYRSEDKILTIEIKKGWKEGTKITFPREGDETPNSIPADIVFV 234
            CTK+MKISR+ +N DG +    DKILTI +KKGWK GTKITFP+EGD+ PN++PADIVF+
Sbjct: 797  CTKKMKISRRVMNEDGHTSSIRDKILTITVKKGWKPGTKITFPKEGDQGPNNVPADIVFI 618

Query: 235  IKDKEHPKFKRDGSNIVYTAKISLREALCGCSLNVPTMDGRNLPMSVTDIVKPGMRRRVI 294
            +KDK HP+F+R+G N+++TA + L  AL G ++++ T+D R L + + DIVKPG ++ V 
Sbjct: 617  VKDKPHPRFRREGLNLIHTANVLLGRALTGTTVDIHTLDDRTLHIPINDIVKPGYKKIVP 438

Query: 295  GYGLPFPKNPDQRGDLLIEFDVSFPDVISAASKEILRKHL 334
            G G+P   +P Q+GDL+IEF++ FP  ++   K+++R  L
Sbjct: 437  GEGMPMSSDPTQKGDLIIEFNIEFPTSLTPERKDLIRTAL 318
>20488
          Length = 3281

 Score =  205 bits (522), Expect = 2e-53,   Method: Compositional matrix adjust.
 Identities = 92/180 (51%), Positives = 135/180 (75%)
 Frame = -2

Query: 155  KQDPPIIHELKVSLEEIYSGCTKRMKISRKRLNPDGRSYRSEDKILTIEIKKGWKEGTKI 214
            KQDPPI  +L ++LEE++ GCTK+MKISR+ +N DG +    DKILTI +KKGWK GTKI
Sbjct: 1714 KQDPPIERDLFLALEEVFHGCTKKMKISRRVMNEDGHTSSIRDKILTITVKKGWKPGTKI 1535

Query: 215  TFPREGDETPNSIPADIVFVIKDKEHPKFKRDGSNIVYTAKISLREALCGCSLNVPTMDG 274
            TFP+EGD+ PN++PADIVF++KDK HP+F+R+G N+++TA + L  AL G ++++ T+D 
Sbjct: 1534 TFPKEGDQGPNNVPADIVFIVKDKPHPRFRREGLNLIHTANVLLGRALTGTTVDIHTLDD 1355

Query: 275  RNLPMSVTDIVKPGMRRRVIGYGLPFPKNPDQRGDLLIEFDVSFPDVISAASKEILRKHL 334
            R L + + DIVKPG ++ V G G+P   +P ++GDL+IEF++ FP  ++   K+++R  L
Sbjct: 1354 RTLHIPINDIVKPGYKKIVPGEGMPMSSDPTZKGDLIIEFNIEFPTSLTPERKDLIRTAL 1175
>14550
          Length = 1395

 Score = 91.3 bits (225), Expect = 6e-19,   Method: Compositional matrix adjust.
 Identities = 61/211 (28%), Positives = 102/211 (48%), Gaps = 36/211 (17%)
 Frame = -2

Query: 160 IIHELKVSLEEIYSG--------------------CTKRMKISRKRLNPDGRSYRS---- 195
           ++ +L V+LEE+YSG                    C  RM+   ++L P GR   S    
Sbjct: 806 VVMDLDVTLEELYSGDFVEVLRYKPVSKPAKGKRKCNCRMETVTQQLGP-GRFQMSQQQV 630

Query: 196 -----------EDKILTIEIKKGWKEGTKITFPREGDETPNSIPADIVFVIKDKEHPKFK 244
                      E+K+L +EI+ G ++G +  F  EG+   +  P D+ F+I+  +H +F+
Sbjct: 629 CDECPNIKFVPEEKVLEVEIEPGMRDGQEYPFVAEGEPHMDGEPGDLRFIIRQVKHARFE 450

Query: 245 RDGSNIVYTAKISLREALCGCSLNVPTMDGRNLPMSVTDIVKPGMRRRVIGYGLPFPKNP 304
           R G ++     +SL++AL G  +++  +DG  + +    I  PG R R    G+P  +N 
Sbjct: 449 RKGDDLYTNVTVSLQDALIGFEMDIVHLDGHKVHVIRDKITWPGARMRKSNEGMPNYENN 270

Query: 305 DQRGDLLIEFDVSFPD-VISAASKEILRKHL 334
           + +G L I FD+ FP   +S   KE L+  L
Sbjct: 269 NVKGSLFITFDIDFPKGTLSEEDKEGLKAIL 177

 Score = 74.3 bits (181), Expect = 7e-14,   Method: Compositional matrix adjust.
 Identities = 34/66 (51%), Positives = 52/66 (78%), Gaps = 1/66 (1%)
 Frame = -1

Query: 2    GKDYYHILGIDKGATDEDVKKAYRKQALKFHPDKNK-SPQAEEKFKEVAEAYEVLSDPKK 60
            G+D+Y ILG+ K A  + +K+AYRK A + HPDKN+  P+AE++F+++  AYEVLSD +K
Sbjct: 1140 GRDFYKILGVSKSADTKQIKRAYRKIAKELHPDKNRDDPEAEQRFQDLGAAYEVLSDEEK 961

Query: 61   REIYDQ 66
            R++YD+
Sbjct: 960  RKVYDR 943

 Score = 28.5 bits (62), Expect = 4.6,   Method: Compositional matrix adjust.
 Identities = 15/39 (38%), Positives = 22/39 (56%), Gaps = 1/39 (2%)
 Frame = -1

Query: 297  GLPFPKNPDQRGDLLIEFDVSFPD-VISAASKEILRKHL 334
            G+P  +N + +G L I FD+ FP   +S   KE L+  L
Sbjct: 1377 GMPNYENNNVKGSLFITFDIDFPKGTLSEEDKEGLKAIL 1261
>26984
          Length = 1107

 Score = 77.4 bits (189), Expect = 8e-15,   Method: Compositional matrix adjust.
 Identities = 35/64 (54%), Positives = 47/64 (73%)
 Frame = -2

Query: 2   GKDYYHILGIDKGATDEDVKKAYRKQALKFHPDKNKSPQAEEKFKEVAEAYEVLSDPKKR 61
           GKD Y ILG+   A+DED+K+ YR+QA+  HPDKN+ P AEE FK +  A+E++ DP KR
Sbjct: 521 GKDPYSILGLRADASDEDIKRYYRRQAVLVHPDKNQEPGAEEAFKILGHAFEMIGDPTKR 342

Query: 62  EIYD 65
           + YD
Sbjct: 341 KEYD 330
>12040
          Length = 1151

 Score = 75.5 bits (184), Expect = 3e-14,   Method: Compositional matrix adjust.
 Identities = 38/110 (34%), Positives = 67/110 (60%), Gaps = 2/110 (1%)
 Frame = -2

Query: 230  DIVFVIKDKEHPKFKRDGSNIVYTAKISLREALCGCSLNVPTMDGRNLPMSVT--DIVKP 287
            DI+ ++ +KEH  F   G++++    + L EALCG    V TMD R+L ++    ++++ 
Sbjct: 1150 DIIILLDEKEHSTFVHAGTDLMMKMPLQLVEALCGFQRIVKTMDDRDLLVATQPGEVIRH 971

Query: 288  GMRRRVIGYGLPFPKNPDQRGDLLIEFDVSFPDVISAASKEILRKHLPAS 337
             M + +   G+P  KNP ++G L+I+F+V FPDVI+ +    L++ LP +
Sbjct: 970  EMTKCIAEEGMPIFKNPMEKGTLIIQFEVIFPDVINPSVIPTLKQCLPPA 821
>07620
          Length = 1775

 Score = 48.9 bits (115), Expect(2) = 3e-13,   Method: Compositional matrix adjust.
 Identities = 20/36 (55%), Positives = 26/36 (72%)
 Frame = +1

Query: 2   GKDYYHILGIDKGATDEDVKKAYRKQALKFHPDKNK 37
            KDYY +L + K  T+ D+KKAYRK AL+ HPDK +
Sbjct: 94  CKDYYEVLDVKKDCTESDMKKAYRKLALQMHPDKTR 201

 Score = 43.1 bits (100), Expect(2) = 3e-13,   Method: Compositional matrix adjust.
 Identities = 28/77 (36%), Positives = 34/77 (44%), Gaps = 2/77 (2%)
 Frame = +3

Query: 33  PDKNKSPQAEEKFKEVAEAYEVLSDPKKREIYDQFXXXXXXXXXXXXXXXXXTFRYTFHG 92
           P +NK+P A + FK++  AY VLSDP KR  YD +                  F     G
Sbjct: 186 PRQNKAPGATDAFKKIGNAYSVLSDPDKRRKYDVYGPELQQPSQHHSEYSNGGFE----G 353

Query: 93  D--PHATFAAFFGGSNP 107
           D  P   F  FFGG  P
Sbjct: 354 DITPEELFNMFFGGGYP 404
>02324
          Length = 2058

 Score = 70.5 bits (171), Expect = 9e-13,   Method: Compositional matrix adjust.
 Identities = 32/64 (50%), Positives = 49/64 (76%), Gaps = 2/64 (3%)
 Frame = +2

Query: 5   YYHILGIDKGATDEDVKKAYRKQALKFHPDKN--KSPQAEEKFKEVAEAYEVLSDPKKRE 62
           +Y +LG+++ A ++D+KKAYRK ALKFHPDKN     +A  +F+ V +AYE+L+DP++R 
Sbjct: 107 HYEVLGVERSADNDDLKKAYRKLALKFHPDKNPDSVEEATAQFRLVQQAYEILTDPQERS 286

Query: 63  IYDQ 66
            YD+
Sbjct: 287 WYDR 298
>13998
          Length = 1075

 Score = 69.7 bits (169), Expect = 1e-12,   Method: Compositional matrix adjust.
 Identities = 37/69 (53%), Positives = 48/69 (69%), Gaps = 6/69 (8%)
 Frame = +1

Query: 3   KDYYHILGIDKGATDEDVKKAYRKQALKFHPDKNKSPQA------EEKFKEVAEAYEVLS 56
           KDYY ILGI + AT++++KKAYRK+AL  HPD++ +  A      E KFKEV EAY +LS
Sbjct: 202 KDYYKILGISRNATEDEIKKAYRKKALVHHPDRHANSSADVRKDEELKFKEVGEAYAILS 381

Query: 57  DPKKREIYD 65
           D  K+  YD
Sbjct: 382 DGAKKTRYD 408
>22505
          Length = 784

 Score = 41.6 bits (96), Expect(2) = 1e-07,   Method: Compositional matrix adjust.
 Identities = 19/38 (50%), Positives = 26/38 (68%)
 Frame = -1

Query: 1   MGKDYYHILGIDKGATDEDVKKAYRKQALKFHPDKNKS 38
           M  D Y ILG+   A ++ + KAYRK+ALK HPDK ++
Sbjct: 661 MKMDLYGILGVGPEANEKQIVKAYRKKALKCHPDKTQT 548

 Score = 32.0 bits (71), Expect(2) = 1e-07,   Method: Compositional matrix adjust.
 Identities = 13/29 (44%), Positives = 20/29 (68%)
 Frame = -3

Query: 38  SPQAEEKFKEVAEAYEVLSDPKKREIYDQ 66
           +P+A E F E+++A EVL+DP  +  YD 
Sbjct: 548 NPKAAELFHELSKALEVLTDPSAKAAYDN 462
>02088
          Length = 1062

 Score = 51.6 bits (122), Expect = 5e-07,   Method: Compositional matrix adjust.
 Identities = 27/66 (40%), Positives = 40/66 (60%), Gaps = 3/66 (4%)
 Frame = +3

Query: 4   DYYHILGIDKGATDEDVKKAYRKQALKFHPDKNKSPQAE---EKFKEVAEAYEVLSDPKK 60
           D Y ++GI + AT ++VKK Y K +L  HPD+  + + E    KF+ + + Y VLSD  K
Sbjct: 108 DLYEVIGIRREATPQEVKKGYHKVSLAVHPDQVSAAEKETATRKFQTLGKVYTVLSDKDK 287

Query: 61  REIYDQ 66
           R  YD+
Sbjct: 288 RAXYDE 305
>13422
          Length = 930

 Score = 44.3 bits (103), Expect = 8e-05,   Method: Compositional matrix adjust.
 Identities = 25/72 (34%), Positives = 41/72 (56%), Gaps = 9/72 (12%)
 Frame = +1

Query: 3   KDYYHILGIDK---GATDEDVKKAYRKQALKFHPDKNKS------PQAEEKFKEVAEAYE 53
           +D+Y +LG+ K    AT + +K+ YR++ L  HPDK ++          + F  ++ AYE
Sbjct: 334 QDHYAVLGLSKLRYKATADHIKRIYRQKVLLHHPDKRRARGLHVENGENDYFLCISRAYE 513

Query: 54  VLSDPKKREIYD 65
           +L DP KR  +D
Sbjct: 514 ILGDPVKRRSFD 549
>15360
          Length = 502

 Score = 41.6 bits (96), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 19/52 (36%), Positives = 37/52 (71%), Gaps = 1/52 (1%)
 Frame = +1

Query: 6   YHILGIDKGATDEDVKKAYRKQALKFHPDKNK-SPQAEEKFKEVAEAYEVLS 56
           +++L I  G+  E +K  Y++ ALK+HP+K+K + +A ++F +V +AY +L+
Sbjct: 61  FNLLDIPAGSDQESLKTKYKQLALKWHPEKHKNAAEAVKQFIQVTQAYRLLA 216
>20155
          Length = 484

 Score = 29.3 bits (64), Expect = 2.4,   Method: Compositional matrix adjust.
 Identities = 14/41 (34%), Positives = 21/41 (51%)
 Frame = +1

Query: 8   ILGIDKGATDEDVKKAYRKQALKFHPDKNKSPQAEEKFKEV 48
           ILG+   A+   +K A+++  L  HPD+  SP    K  E 
Sbjct: 151 ILGVSPSASKVKIKDAHKRIMLLNHPDRGGSPYLAAKVNEA 273
>33510
          Length = 501

 Score = 28.5 bits (62), Expect = 3.7,   Method: Compositional matrix adjust.
 Identities = 19/59 (32%), Positives = 29/59 (49%), Gaps = 4/59 (6%)
 Frame = +3

Query: 10  GIDKGATDEDVKKAYRKQALKFHPDK-NKSPQ---AEEKFKEVAEAYEVLSDPKKREIY 64
           G+    + + VKK YRK  L  HPDK +  P    A+  F E+ +A+    D   + +Y
Sbjct: 276 GMHDLVSADQVKKVYRKAVLSVHPDKLHDDPHEALAKLIFMELNDAWAKFEDEGMKSLY 452
>18150
          Length = 768

 Score = 28.5 bits (62), Expect = 4.1,   Method: Compositional matrix adjust.
 Identities = 11/18 (61%), Positives = 14/18 (77%)
 Frame = +2

Query: 50  EAYEVLSDPKKREIYDQF 67
           EA+E+LSD  KR IYD +
Sbjct: 119 EAHEILSDKHKRTIYDTY 172
>38321
          Length = 1059

 Score = 28.5 bits (62), Expect = 4.6,   Method: Compositional matrix adjust.
 Identities = 15/39 (38%), Positives = 22/39 (56%), Gaps = 1/39 (2%)
 Frame = -1

Query: 297  GLPFPKNPDQRGDLLIEFDVSFPD-VISAASKEILRKHL 334
            G+P  +N + +G L I FD+ FP   +S   KE L+  L
Sbjct: 1041 GMPNYENNNVKGSLFITFDIDFPKGTLSEEDKEGLKAIL 925
>05107
          Length = 1230

 Score = 28.1 bits (61), Expect = 6.0,   Method: Compositional matrix adjust.
 Identities = 13/39 (33%), Positives = 22/39 (56%)
 Frame = -1

Query: 163 ELKVSLEEIYSGCTKRMKISRKRLNPDGRSYRSEDKILT 201
           E+  +L+   S  +  + ++R R  P+GR Y + D ILT
Sbjct: 648 EVSAALDSARSSMS*LLPLTRSRTLPEGRGYMTLDTILT 532
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6755256|ref|NP_035354.1| muscle glycogen
phosphorylase [Mus musculus]
         (842 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

18438                                                                 150   1e-63
19923                                                                 223   2e-58
10391                                                                  31   1.6  
>18438
          Length = 457

 Score =  150 bits (379), Expect(2) = 1e-63,   Method: Compositional matrix adjust.
 Identities = 73/101 (72%), Positives = 80/101 (79%), Gaps = 1/101 (0%)
 Frame = -1

Query: 192 KARPEFTLPVHFYGR-VEHTSQGAKWVDTQVVLAMPYDTPVPGYRNNVVNTMRLWSAKAP 250
           KARPE+ LPV+FYGR V+      KWVDTQVVLAMPYDTP+PGY NN VNT+RLWSA+AP
Sbjct: 457 KARPEYMLPVNFYGRCVQDGDDRIKWVDTQVVLAMPYDTPIPGYGNNTVNTLRLWSARAP 278

Query: 251 NDFNLKDFNVGGYIQAVLDRNLAENISRVLYPNDNFFEGKE 291
           N FNL  FN G YI AV DRNLAENISRVLYPNDNF   + 
Sbjct: 277 NSFNLHFFNSGEYITAVCDRNLAENISRVLYPNDNFSRARN 155

 Score =  112 bits (281), Expect(2) = 1e-63,   Method: Composition-based stats.
 Identities = 52/57 (91%), Positives = 55/57 (96%)
 Frame = -3

Query: 286 FFEGKELRLKQEYFVVAATLQDIIRRFKSSKFGSRDPVRTNFDAFPDKVAIQLNDTH 342
           FFEGKELRLKQEYF+VAATLQDIIRRFKSS+FG RDPVRT+FD FPDKVAIQLNDTH
Sbjct: 173 FFEGKELRLKQEYFLVAATLQDIIRRFKSSRFGCRDPVRTSFDTFPDKVAIQLNDTH 3
>19923
          Length = 471

 Score =  223 bits (569), Expect = 2e-58,   Method: Compositional matrix adjust.
 Identities = 100/156 (64%), Positives = 130/156 (83%)
 Frame = +3

Query: 508 IGEDYISDLDQLRKLLSYVDDEAFIRDVAKVKQENKLKFSAYLEREYKVHINPNSLFDVQ 567
           IGE ++++L +LR+L     +E  +R + KVKQENK+K +AY+E+ Y V  NP S+FD+Q
Sbjct: 3   IGETWVTNLAELRRLEPLSKEETLLRSIMKVKQENKMKLTAYMEQNYGVKANPASMFDMQ 182

Query: 568 VKRIHEYKRQLLNCLHIITLYNRIKREPNRFMVPRTIMIGGKAAPGYHMAKMIIKLITAI 627
           VKRIHEYKRQL+NCLH+IT+YNRIK+ P+   VPRT+MIGGKAAPGYHMAK+IIKLI  +
Sbjct: 183 VKRIHEYKRQLMNCLHVITIYNRIKKNPSIPFVPRTVMIGGKAAPGYHMAKLIIKLINNV 362

Query: 628 GDVVNHDPAVGDRLRVIFLENYRVSLAEKVIPAADL 663
           G  +N+DP VGDRL++++LENYRVSLAEK+IPAADL
Sbjct: 363 GRTINNDPIVGDRLKLVYLENYRVSLAEKIIPAADL 470
>10391
          Length = 469

 Score = 31.2 bits (69), Expect = 1.6,   Method: Composition-based stats.
 Identities = 12/18 (66%), Positives = 14/18 (77%)
 Frame = +1

Query: 824 EIWGVEPSRQRLPAPDEK 841
           EIWG+EPS   +PAP EK
Sbjct: 1   EIWGMEPSSHVIPAPFEK 54
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6678940|ref|NP_032655.1| Musashi homolog 1 [Mus
musculus]
         (362 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

11019                                                                 238   2e-63
19868                                                                 223   1e-58
03000                                                                 146   1e-35
03406                                                                 142   3e-34
26197                                                                  92   2e-28
01937                                                                 121   4e-28
16016                                                                  96   2e-25
31618                                                                  99   3e-21
32386                                                                  97   8e-21
12350                                                                  96   3e-20
00817                                                                  83   2e-16
33516                                                                  78   6e-15
02415                                                                  75   5e-14
11687                                                                  70   2e-12
23322                                                                  68   5e-12
17681                                                                  68   5e-12
24983                                                                  66   2e-11
10194                                                                  59   4e-09
23655                                                                  39   5e-08
16427                                                                  54   8e-08
02343                                                                  52   3e-07
00302                                                                  51   7e-07
05273                                                                  50   1e-06
09968                                                                  46   2e-05
17775                                                                  46   2e-05
28652                                                                  44   1e-04
00556                                                                  43   2e-04
30672                                                                  43   2e-04
13457                                                                  43   2e-04
32733                                                                  42   3e-04
02502                                                                  42   5e-04
31310                                                                  41   6e-04
08958                                                                  41   6e-04
00029                                                                  40   0.001
11126                                                                  39   0.004
13822                                                                  38   0.008
23720                                                                  38   0.008
04988                                                                  37   0.012
25691                                                                  37   0.017
25950                                                                  35   0.032
35180                                                                  34   0.11 
28455                                                                  34   0.11 
39789                                                                  32   0.43 
11108                                                                  30   1.0  
19556                                                                  30   1.1  
30934                                                                  30   1.7  
21869                                                                  30   1.8  
33504                                                                  30   1.9  
02064                                                                  30   1.9  
35379                                                                  26   2.4  
12096                                                                  28   6.3  
>11019
          Length = 552

 Score =  238 bits (608), Expect = 2e-63,   Method: Compositional matrix adjust.
 Identities = 113/184 (61%), Positives = 139/184 (75%), Gaps = 21/184 (11%)
 Frame = -1

Query: 24  IGGLSWQTTQEGLREYFGQFGEVKECLVMRDPLTKRSRGFGFVTFMDQAGVDKVLAQSRH 83
           IGGLSWQTT E LR YF +FGE+KE +VM+DP +KRSRGFGFVT+ D + VD VLA   H
Sbjct: 552 IGGLSWQTTTETLRSYFEKFGEIKESMVMKDPTSKRSRGFGFVTYKDPSNVDNVLANGPH 373

Query: 84  ELDSKT---------------------IDPKVAFPRRAQPKMVTRTKKIFVGGLSVNTTV 122
            +DSKT                     +DPKVAFPR++ P+MVT+TKKIFVGGLS +TTV
Sbjct: 372 CIDSKTLNFSNMTTFYSNQDLLPYPPQVDPKVAFPRKSNPRMVTKTKKIFVGGLSSSTTV 193

Query: 123 EDVKHYFEQFGKVDDAMLMFDKTTNRHRGFGFVTFESEDIVEKVCEIHFHEINNKMVECK 182
           ED+K+YF+ +G +++A LMFDK T+RHRGF FVTF++E  V+KVCEIHFHEIN+KMVE K
Sbjct: 192 EDIKNYFKAYGTIEEATLMFDKVTSRHRGFAFVTFDNESTVDKVCEIHFHEINSKMVETK 13

Query: 183 KAQP 186
           KAQP
Sbjct: 12  KAQP 1

 Score = 75.5 bits (184), Expect = 3e-14,   Method: Compositional matrix adjust.
 Identities = 35/77 (45%), Positives = 51/77 (66%)
 Frame = -1

Query: 21  KMFIGGLSWQTTQEGLREYFGQFGEVKECLVMRDPLTKRSRGFGFVTFMDQAGVDKVLAQ 80
           K+F+GGLS  TT E ++ YF  +G ++E  +M D +T R RGF FVTF +++ VDKV   
Sbjct: 231 KIFVGGLSSSTTVEDIKNYFKAYGTIEEATLMFDKVTSRHRGFAFVTFDNESTVDKVCEI 52

Query: 81  SRHELDSKTIDPKVAFP 97
             HE++SK ++ K A P
Sbjct: 51  HFHEINSKMVETKKAQP 1
>19868
          Length = 434

 Score =  223 bits (567), Expect = 1e-58,   Method: Compositional matrix adjust.
 Identities = 104/136 (76%), Positives = 119/136 (87%)
 Frame = +2

Query: 21  KMFIGGLSWQTTQEGLREYFGQFGEVKECLVMRDPLTKRSRGFGFVTFMDQAGVDKVLAQ 80
           KMF+GGLSWQT+ E LR+YF +FGE+ E +VM+DP T+RSRGFGF+TF D A VDKVLAQ
Sbjct: 2   KMFVGGLSWQTSPESLRDYFNKFGEITEVMVMKDPTTRRSRGFGFITFGDPASVDKVLAQ 181

Query: 81  SRHELDSKTIDPKVAFPRRAQPKMVTRTKKIFVGGLSVNTTVEDVKHYFEQFGKVDDAML 140
           + HELD K IDPKVAFPRRA P+MVTRTKKIFVGGLS  TT+EDVK+YFEQFG ++DAML
Sbjct: 182 ATHELDGKKIDPKVAFPRRAHPRMVTRTKKIFVGGLSAPTTLEDVKNYFEQFGPIEDAML 361

Query: 141 MFDKTTNRHRGFGFVT 156
           MFDK TNRHRGFGFVT
Sbjct: 362 MFDKQTNRHRGFGFVT 409

 Score = 70.9 bits (172), Expect = 7e-13,   Method: Compositional matrix adjust.
 Identities = 35/79 (44%), Positives = 51/79 (64%)
 Frame = +2

Query: 110 KIFVGGLSVNTTVEDVKHYFEQFGKVDDAMLMFDKTTNRHRGFGFVTFESEDIVEKVCEI 169
           K+FVGGLS  T+ E ++ YF +FG++ + M+M D TT R RGFGF+TF     V+KV   
Sbjct: 2   KMFVGGLSWQTSPESLRDYFNKFGEITEVMVMKDPTTRRSRGFGFITFGDPASVDKVLAQ 181

Query: 170 HFHEINNKMVECKKAQPKE 188
             HE++ K ++ K A P+ 
Sbjct: 182 ATHELDGKKIDPKVAFPRR 238
>03000
          Length = 778

 Score =  146 bits (369), Expect = 1e-35,   Method: Compositional matrix adjust.
 Identities = 72/172 (41%), Positives = 110/172 (63%), Gaps = 2/172 (1%)
 Frame = +3

Query: 21  KMFIGGLSWQTTQEGLREYFGQFGEVKECLVMRDPLTKRSRGFGFVTFMDQAGVDKVLAQ 80
           K+FIGGLS++T ++ LR +F  +GE+ +C+VMRD  +KRSRGFGF+T+ D   +D+  A 
Sbjct: 90  KLFIGGLSYETDEDSLRSHFETWGEIVDCIVMRDSNSKRSRGFGFITYKDAESIDQAQAN 269

Query: 81  SRHELDSKTIDPKVAFPRR--AQPKMVTRTKKIFVGGLSVNTTVEDVKHYFEQFGKVDDA 138
             H++D + +D K A PR    + ++    KK+FVGG+  +TT + ++  F +FG++   
Sbjct: 270 RPHKIDGREVDTKRAMPREESGRSEVQQSVKKMFVGGVKEDTTEDMIRDTFNEFGEITGV 449

Query: 139 MLMFDKTTNRHRGFGFVTFESEDIVEKVCEIHFHEINNKMVECKKAQPKEVM 190
            L+ DK T ++RGF FVTF   D V+K      H++N + VE KKAQ K  M
Sbjct: 450 DLIQDKGTGKNRGFCFVTFGDHDSVDKAVLKKRHDLNGRQVEVKKAQSKNDM 605

 Score = 65.1 bits (157), Expect = 5e-11,   Method: Compositional matrix adjust.
 Identities = 33/106 (31%), Positives = 61/106 (57%)
 Frame = +3

Query: 109 KKIFVGGLSVNTTVEDVKHYFEQFGKVDDAMLMFDKTTNRHRGFGFVTFESEDIVEKVCE 168
           +K+F+GGLS  T  + ++ +FE +G++ D ++M D  + R RGFGF+T++  + +++   
Sbjct: 87  RKLFIGGLSYETDEDSLRSHFETWGEIVDCIVMRDSNSKRSRGFGFITYKDAESIDQAQA 266

Query: 169 IHFHEINNKMVECKKAQPKEVMSPTGSARGRSRVMPYGMDAFMLGI 214
              H+I+ + V+ K+A P+E         GRS V       F+ G+
Sbjct: 267 NRPHKIDGREVDTKRAMPRE-------ESGRSEVQQSVKKMFVGGV 383
>03406
          Length = 1292

 Score =  142 bits (357), Expect = 3e-34,   Method: Compositional matrix adjust.
 Identities = 78/187 (41%), Positives = 108/187 (57%)
 Frame = +3

Query: 5   APQPGLASPDSPHDPCKMFIGGLSWQTTQEGLREYFGQFGEVKECLVMRDPLTKRSRGFG 64
           A + G  + +   D  K+F+GGLSW+T  + LREYF +FGEV  C +  D  + +SRGFG
Sbjct: 195 AMETGGDAEEENEDDRKIFVGGLSWETXSKHLREYFEKFGEVTSCTLKTDLDSGKSRGFG 374

Query: 65  FVTFMDQAGVDKVLAQSRHELDSKTIDPKVAFPRRAQPKMVTRTKKIFVGGLSVNTTVED 124
           FV F + A VD V+    H+L  + IDPK A PR+         +KIFVG L      ED
Sbjct: 375 FVVFKEAATVDAVVKNKEHKLQGRKIDPKPANPRKG-------MRKIFVGKLDPGVPQED 533

Query: 125 VKHYFEQFGKVDDAMLMFDKTTNRHRGFGFVTFESEDIVEKVCEIHFHEINNKMVECKKA 184
           V+ YF +FGKV +  L +DK  ++ R F FV F+++  V+KV E   H+I  + V+ KKA
Sbjct: 534 VESYFAKFGKVVNVELPYDKVKDQRRAFCFVEFDNDKTVKKVLEQTSHKIGGQEVDVKKA 713

Query: 185 QPKEVMS 191
            P    S
Sbjct: 714 TPNPAQS 734
>26197
          Length = 1365

 Score = 92.4 bits (228), Expect(2) = 2e-28,   Method: Compositional matrix adjust.
 Identities = 44/103 (42%), Positives = 61/103 (59%)
 Frame = -2

Query: 5    APQPGLASPDSPHDPCKMFIGGLSWQTTQEGLREYFGQFGEVKECLVMRDPLTKRSRGFG 64
            + Q G    +   D  K+F+GGLSW+T+ + LREYF +FGEV  C +  D  + +SRGFG
Sbjct: 1343 STQSGHYGREENEDDRKIFVGGLSWETSSKHLREYFEKFGEVTSCTLKTDLDSGKSRGFG 1164

Query: 65   FVTFMDQAGVDKVLAQSRHELDSKTIDPKVAFPRRAQPKMVTR 107
            FV F +   VD V+    H+L  + IDPK A PR+   K+  R
Sbjct: 1163 FVVFKEAVTVDAVVKNKEHKLQGRKIDPKPANPRKGMRKIFCR 1035

 Score = 50.8 bits (120), Expect(2) = 2e-28,   Method: Compositional matrix adjust.
 Identities = 28/70 (40%), Positives = 41/70 (58%)
 Frame = -3

Query: 110  KIFVGGLSVNTTVEDVKHYFEQFGKVDDAMLMFDKTTNRHRGFGFVTFESEDIVEKVCEI 169
            + FVG L      EDV+ YF +FGKV +  L +DK  ++ R F FV F+++  V+KV E 
Sbjct: 1048 RFFVGKLDPGVPQEDVESYFAKFGKVVNVELPYDKVKDQRRAFCFVEFDNDKTVKKVLEQ 869

Query: 170  HFHEINNKMV 179
              H+I  + V
Sbjct: 868  TSHKIGGQEV 839

 Score = 62.0 bits (149), Expect = 4e-10,   Method: Compositional matrix adjust.
 Identities = 31/82 (37%), Positives = 50/82 (60%)
 Frame = -2

Query: 109  KKIFVGGLSVNTTVEDVKHYFEQFGKVDDAMLMFDKTTNRHRGFGFVTFESEDIVEKVCE 168
            +KIFVGGLS  T+ + ++ YFE+FG+V    L  D  + + RGFGFV F+    V+ V +
Sbjct: 1298 RKIFVGGLSWETSSKHLREYFEKFGEVTSCTLKTDLDSGKSRGFGFVVFKEAVTVDAVVK 1119

Query: 169  IHFHEINNKMVECKKAQPKEVM 190
               H++  + ++ K A P++ M
Sbjct: 1118 NKEHKLQGRKIDPKPANPRKGM 1053

 Score = 43.5 bits (101), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 22/65 (33%), Positives = 34/65 (52%)
 Frame = -3

Query: 21   KMFIGGLSWQTTQEGLREYFGQFGEVKECLVMRDPLTKRSRGFGFVTFMDQAGVDKVLAQ 80
            + F+G L     QE +  YF +FG+V    +  D +  + R F FV F +   V KVL Q
Sbjct: 1048 RFFVGKLDPGVPQEDVESYFAKFGKVVNVELPYDKVKDQRRAFCFVEFDNDKTVKKVLEQ 869

Query: 81   SRHEL 85
            + H++
Sbjct: 868  TSHKI 854
>01937
          Length = 1320

 Score =  121 bits (304), Expect = 4e-28,   Method: Compositional matrix adjust.
 Identities = 61/109 (55%), Positives = 77/109 (70%)
 Frame = -1

Query: 60   SRGFGFVTFMDQAGVDKVLAQSRHELDSKTIDPKVAFPRRAQPKMVTRTKKIFVGGLSVN 119
            +RGFGFVT+ D + VD VLA   H +DSKT              MVT+T KIFVGGLS +
Sbjct: 1320 TRGFGFVTYKDPSNVDNVLANGPHCIDSKT--------------MVTKTSKIFVGGLSSS 1183

Query: 120  TTVEDVKHYFEQFGKVDDAMLMFDKTTNRHRGFGFVTFESEDIVEKVCE 168
            TTVED K+YF+ +G +++A LMFDK T+RHRGF FVTF++E  V+KVCE
Sbjct: 1182 TTVEDXKNYFKAYGTIEEATLMFDKVTSRHRGFAFVTFDNESTVDKVCE 1036

 Score = 63.2 bits (152), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 28/57 (49%), Positives = 39/57 (68%)
 Frame = -1

Query: 21   KMFIGGLSWQTTQEGLREYFGQFGEVKECLVMRDPLTKRSRGFGFVTFMDQAGVDKV 77
            K+F+GGLS  TT E  + YF  +G ++E  +M D +T R RGF FVTF +++ VDKV
Sbjct: 1212 KIFVGGLSSSTTVEDXKNYFKAYGTIEEATLMFDKVTSRHRGFAFVTFDNESTVDKV 1042

 Score = 39.3 bits (90), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 24/72 (33%), Positives = 32/72 (44%), Gaps = 16/72 (22%)
 Frame = -3

Query: 158  ESEDIVEKVCEIHFHE---------------INNKMVECKKAQPKEVMS-PTGSARGRSR 201
            +S+    + C  H  +                  KMVE KKAQPKEVM+ PT  ARGR  
Sbjct: 1111 QSDQSASRFCICHVRQRIHCGQSV*KSTSMKSTQKMVETKKAQPKEVMAGPTTLARGRGL 932

Query: 202  VMPYGMDAFMLG 213
               Y +  ++ G
Sbjct: 931  AQRYSVAGYLPG 896
>16016
          Length = 1364

 Score = 96.3 bits (238), Expect(2) = 2e-25,   Method: Compositional matrix adjust.
 Identities = 47/109 (43%), Positives = 71/109 (65%)
 Frame = -2

Query: 21   KMFIGGLSWQTTQEGLREYFGQFGEVKECLVMRDPLTKRSRGFGFVTFMDQAGVDKVLAQ 80
            K+FIGG+   T +  LR YF ++G+++EC+V++DP TKRSR F F+TF +   VD+V   
Sbjct: 1306 KVFIGGMHPDTDESSLRSYFEKYGDIRECIVVKDPATKRSRCFSFITFGNAENVDEVQKD 1127

Query: 81   SRHELDSKTIDPKVAFPRRAQPKMVTRTKKIFVGGLSVNTTVEDVKHYF 129
              H +D +T++ K A P R   +   +TKK+FVGGL  +TT E ++  F
Sbjct: 1126 RPHTIDGRTVETKRAMP-REDTENHHQTKKMFVGGLKDDTTEEMLRKEF 983

 Score = 37.0 bits (84), Expect(2) = 2e-25,   Method: Compositional matrix adjust.
 Identities = 19/51 (37%), Positives = 30/51 (58%)
 Frame = -1

Query: 140 LMFDKTTNRHRGFGFVTFESEDIVEKVCEIHFHEINNKMVECKKAQPKEVM 190
           ++ DK+T + RGF FV+F+  D V+K       +IN + VE KKA  +  +
Sbjct: 959 MIKDKSTGKFRGFCFVSFDDCDTVDKHAIHKCFKINGRHVEAKKASQQSEL 807

 Score = 62.0 bits (149), Expect = 4e-10,   Method: Compositional matrix adjust.
 Identities = 28/82 (34%), Positives = 52/82 (63%)
 Frame = -2

Query: 107  RTKKIFVGGLSVNTTVEDVKHYFEQFGKVDDAMLMFDKTTNRHRGFGFVTFESEDIVEKV 166
            R +K+F+GG+  +T    ++ YFE++G + + +++ D  T R R F F+TF + + V++V
Sbjct: 1315 RNRKVFIGGMHPDTDESSLRSYFEKYGDIRECIVVKDPATKRSRCFSFITFGNAENVDEV 1136

Query: 167  CEIHFHEINNKMVECKKAQPKE 188
             +   H I+ + VE K+A P+E
Sbjct: 1135 QKDRPHTIDGRTVETKRAMPRE 1070

 Score = 30.0 bits (66), Expect(2) = 0.002,   Method: Compositional matrix adjust.
 Identities = 15/34 (44%), Positives = 22/34 (64%), Gaps = 1/34 (2%)
 Frame = -2

Query: 14   DSPHDPCKMFIGGLSWQTTQEGLR-EYFGQFGEV 46
            ++ H   KMF+GGL   TT+E LR E+ G+  E+
Sbjct: 1063 ENHHQTKKMFVGGLKDDTTEEMLRKEFTGKITEL 962

 Score = 28.5 bits (62), Expect(2) = 0.002,   Method: Compositional matrix adjust.
 Identities = 14/45 (31%), Positives = 25/45 (55%)
 Frame = -1

Query: 51  VMRDPLTKRSRGFGFVTFMDQAGVDKVLAQSRHELDSKTIDPKVA 95
           +++D  T + RGF FV+F D   VDK       +++ + ++ K A
Sbjct: 959 MIKDKSTGKFRGFCFVSFDDCDTVDKHAIHKCFKINGRHVEAKKA 825
>31618
          Length = 716

 Score = 99.0 bits (245), Expect = 3e-21,   Method: Compositional matrix adjust.
 Identities = 57/172 (33%), Positives = 88/172 (51%), Gaps = 9/172 (5%)
 Frame = +1

Query: 1   METDAPQPGLASPDSPHDPC---------KMFIGGLSWQTTQEGLREYFGQFGEVKECLV 51
           ME   P P L        P          K+F+GGLSW+TT++ LR++FG++GE++   V
Sbjct: 208 MENRLPLPALQMAAQKMQPLRVTSVMMTEKLFVGGLSWETTEKELRDHFGKYGEIESINV 387

Query: 52  MRDPLTKRSRGFGFVTFMDQAGVDKVLAQSRHELDSKTIDPKVAFPRRAQPKMVTRTKKI 111
             DP T RSRGF F+ F +   +D+V A   H ++SK +DPK   PR A  + ++     
Sbjct: 388 KTDPQTGRSRGFAFIVFTNTEAIDQVSAAEEHIINSKKVDPKKK-PRLAMARFLSVA*PQ 564

Query: 112 FVGGLSVNTTVEDVKHYFEQFGKVDDAMLMFDKTTNRHRGFGFVTFESEDIV 163
            +       T  ++ +  E         + FDK  +  +GF F+TF+SE +V
Sbjct: 565 RLAMRKSKPTSVNLDNIVE-------VEMPFDKQKSHRKGFXFITFDSEQVV 699

 Score = 62.8 bits (151), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 34/97 (35%), Positives = 60/97 (61%), Gaps = 3/97 (3%)
 Frame = +1

Query: 98  RRAQPKMVTR---TKKIFVGGLSVNTTVEDVKHYFEQFGKVDDAMLMFDKTTNRHRGFGF 154
           ++ QP  VT    T+K+FVGGLS  TT ++++ +F ++G+++   +  D  T R RGF F
Sbjct: 250 QKMQPLRVTSVMMTEKLFVGGLSWETTEKELRDHFGKYGEIESINVKTDPQTGRSRGFAF 429

Query: 155 VTFESEDIVEKVCEIHFHEINNKMVECKKAQPKEVMS 191
           + F + + +++V     H IN+K V+ KK +P+  M+
Sbjct: 430 IVFTNTEAIDQVSAAEEHIINSKKVDPKK-KPRLAMA 537
>32386
          Length = 674

 Score = 97.4 bits (241), Expect = 8e-21,   Method: Compositional matrix adjust.
 Identities = 44/100 (44%), Positives = 67/100 (67%), Gaps = 2/100 (2%)
 Frame = +1

Query: 21  KMFIGGLSWQTTQEGLREYFGQFGEVKECLVMRDPLTKRSRGFGFVTFMDQAGVDKVLAQ 80
           K+FIGGLS++T ++ LR +F  +GE+ +C+VMRD  +KRSRGFGF+T+ D   +D+  A 
Sbjct: 304 KLFIGGLSYETDEDSLRSHFETWGEIVDCIVMRDSNSKRSRGFGFITYKDAESIDQAQAN 483

Query: 81  SRHELDSKTIDPKVAFPRR--AQPKMVTRTKKIFVGGLSV 118
             H++D + +D K A PR    + ++    KK+FVG LS 
Sbjct: 484 RPHKIDGREVDTKRAMPREESGRSEVQQSVKKMFVGSLSC 603

 Score = 65.9 bits (159), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 27/80 (33%), Positives = 53/80 (66%)
 Frame = +1

Query: 109 KKIFVGGLSVNTTVEDVKHYFEQFGKVDDAMLMFDKTTNRHRGFGFVTFESEDIVEKVCE 168
           +K+F+GGLS  T  + ++ +FE +G++ D ++M D  + R RGFGF+T++  + +++   
Sbjct: 301 RKLFIGGLSYETDEDSLRSHFETWGEIVDCIVMRDSNSKRSRGFGFITYKDAESIDQAQA 480

Query: 169 IHFHEINNKMVECKKAQPKE 188
              H+I+ + V+ K+A P+E
Sbjct: 481 NRPHKIDGREVDTKRAMPRE 540
>12350
          Length = 975

 Score = 95.5 bits (236), Expect = 3e-20,   Method: Compositional matrix adjust.
 Identities = 50/165 (30%), Positives = 89/165 (53%)
 Frame = -2

Query: 2   ETDAPQPGLASPDSPHDPCKMFIGGLSWQTTQEGLREYFGQFGEVKECLVMRDPLTKRSR 61
           ++D P P +    S      + + GL W++T++ LR YF QFG++    V +DP T +S+
Sbjct: 674 KSDHPGPKVVKSSSRQKCSDLIVLGLPWKSTEDDLRSYFSQFGDLLMVQVKKDPKTGQSK 495

Query: 62  GFGFVTFMDQAGVDKVLAQSRHELDSKTIDPKVAFPRRAQPKMVTRTKKIFVGGLSVNTT 121
           GFGF+ F +     K +AQ RH +D +  D ++   +    +++ R  KIFVG  + + T
Sbjct: 494 GFGFIRFAEYESQLKCMAQ-RHMIDGRWCDVRIPNSKEGAQQLMNR--KIFVGRCTDDMT 324

Query: 122 VEDVKHYFEQFGKVDDAMLMFDKTTNRHRGFGFVTFESEDIVEKV 166
            +D++ +F +FG+V D  +         R F FV+F   ++ + +
Sbjct: 323 ADDLRQFFSKFGEVVDVFI-----PRPFRAFAFVSFADPEVAQSL 204
>00817
          Length = 2606

 Score = 82.8 bits (203), Expect = 2e-16,   Method: Compositional matrix adjust.
 Identities = 35/78 (44%), Positives = 53/78 (67%)
 Frame = -2

Query: 21   KMFIGGLSWQTTQEGLREYFGQFGEVKECLVMRDPLTKRSRGFGFVTFMDQAGVDKVLAQ 80
            K+FIGG+   T +  LR YF ++G+++EC+V++DP TKRSR F F+TF +   VD+V   
Sbjct: 2548 KVFIGGMHPDTDESSLRSYFEKYGDIRECIVVKDPATKRSRCFSFITFGNAENVDEVQKD 2369

Query: 81   SRHELDSKTIDPKVAFPR 98
              H +D +T++ K A PR
Sbjct: 2368 RPHTIDGRTVETKRAMPR 2315

 Score = 62.4 bits (150), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 28/82 (34%), Positives = 52/82 (63%)
 Frame = -2

Query: 107  RTKKIFVGGLSVNTTVEDVKHYFEQFGKVDDAMLMFDKTTNRHRGFGFVTFESEDIVEKV 166
            R +K+F+GG+  +T    ++ YFE++G + + +++ D  T R R F F+TF + + V++V
Sbjct: 2557 RNRKVFIGGMHPDTDESSLRSYFEKYGDIRECIVVKDPATKRSRCFSFITFGNAENVDEV 2378

Query: 167  CEIHFHEINNKMVECKKAQPKE 188
             +   H I+ + VE K+A P+E
Sbjct: 2377 QKDRPHTIDGRTVETKRAMPRE 2312
>33516
          Length = 449

 Score = 77.8 bits (190), Expect = 6e-15,   Method: Compositional matrix adjust.
 Identities = 38/89 (42%), Positives = 53/89 (59%), Gaps = 10/89 (11%)
 Frame = +1

Query: 17  HDPCKMFIGGLSWQTTQEGLREYFGQFGEVKECLVMRDPLTKRSRGFGFVTFMDQAGVDK 76
            +P K+F+GGLSW T Q+ L+ YF QFGE+ +C+VM +  T +SRGFGFV+F D + VD 
Sbjct: 145 EEPGKIFVGGLSWDTDQDSLQGYFSQFGEITDCIVMMNQQTGKSRGFGFVSFKDPSTVDV 324

Query: 77  VLAQSR----------HELDSKTIDPKVA 95
           +L+  +            L  K I PK  
Sbjct: 325 ILSSKKPCY*WQNCRCQSLQRKRISPKAT 411

 Score = 57.8 bits (138), Expect = 7e-09,   Method: Compositional matrix adjust.
 Identities = 25/57 (43%), Positives = 40/57 (70%)
 Frame = +1

Query: 110 KIFVGGLSVNTTVEDVKHYFEQFGKVDDAMLMFDKTTNRHRGFGFVTFESEDIVEKV 166
           KIFVGGLS +T  + ++ YF QFG++ D ++M ++ T + RGFGFV+F+    V+ +
Sbjct: 157 KIFVGGLSWDTDQDSLQGYFSQFGEITDCIVMMNQQTGKSRGFGFVSFKDPSTVDVI 327
>02415
          Length = 2763

 Score = 74.7 bits (182), Expect = 5e-14,   Method: Compositional matrix adjust.
 Identities = 34/96 (35%), Positives = 53/96 (55%)
 Frame = -1

Query: 1    METDAPQPGLASPDSPHDPCKMFIGGLSWQTTQEGLREYFGQFGEVKECLVMRDPLTKRS 60
            M T +  P L +        K+F+GGL + TT   LREYF +FG++ E +V+ D  T +S
Sbjct: 1983 MATTSINPALITGQKDTTYTKIFVGGLPYHTTDHSLREYFDKFGDIDEAVVITDRQTGKS 1804

Query: 61   RGFGFVTFMDQAGVDKVLAQSRHELDSKTIDPKVAF 96
            RG+GFVT  D+ G D+        +D +  +  +A+
Sbjct: 1803 RGYGFVTMADRTGADRACKDPNPIIDGRKANVNLAY 1696

 Score = 63.2 bits (152), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 30/90 (33%), Positives = 52/90 (57%), Gaps = 5/90 (5%)
 Frame = -1

Query: 101  QPKMVTRTK-----KIFVGGLSVNTTVEDVKHYFEQFGKVDDAMLMFDKTTNRHRGFGFV 155
             P ++T  K     KIFVGGL  +TT   ++ YF++FG +D+A+++ D+ T + RG+GFV
Sbjct: 1965 NPALITGQKDTTYTKIFVGGLPYHTTDHSLREYFDKFGDIDEAVVITDRQTGKSRGYGFV 1786

Query: 156  TFESEDIVEKVCEIHFHEINNKMVECKKAQ 185
            T       ++ C+       N +++ +KA 
Sbjct: 1785 TMADRTGADRACKDP-----NPIIDGRKAN 1711
>11687
          Length = 676

 Score = 69.7 bits (169), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 47/155 (30%), Positives = 75/155 (48%), Gaps = 8/155 (5%)
 Frame = +3

Query: 13  PDSPHDPCKMFIGGLSWQTTQEGLREYFGQFGEVKECLVMRDPLTKRSRGFGFVTFMDQA 72
           PD+  D  KMF+G +     +  LR+ F  +G V    ++RD  T +S+G  FVTF  + 
Sbjct: 135 PDA--DSIKMFVGQIPRNMDENELRKMFEDYGPVHSLNILRDKNTGQSKGCCFVTFFTR- 305

Query: 73  GVDKVLAQSRHELDSKTIDPKVAFPRRAQP--------KMVTRTKKIFVGGLSVNTTVED 124
              K    +++ L +    P +  P + +P        +     +K+FVG LS   +  D
Sbjct: 306 ---KAALDAQNALHNVKTMPMMHHPVQMKPADSEKRNGERNVEERKLFVGMLSKKLSEND 476

Query: 125 VKHYFEQFGKVDDAMLMFDKTTNRHRGFGFVTFES 159
           V+  FE FG +DD  ++ D +    RG  F+TF S
Sbjct: 477 VRMLFESFGSIDDCTVLRD-SNGTSRGCAFITFAS 578
>23322
          Length = 471

 Score = 68.2 bits (165), Expect = 5e-12,   Method: Compositional matrix adjust.
 Identities = 39/100 (39%), Positives = 58/100 (58%), Gaps = 2/100 (2%)
 Frame = -2

Query: 93  KVAFPRR--AQPKMVTRTKKIFVGGLSVNTTVEDVKHYFEQFGKVDDAMLMFDKTTNRHR 150
           K A PR    + ++    KK+FVGG+  +TT + ++  F +FG++    L+ DK T ++R
Sbjct: 464 KRAMPREESGRSEVQQSVKKMFVGGVKEDTTEDMIRDTFNEFGEITGVDLIQDKGTGKNR 285

Query: 151 GFGFVTFESEDIVEKVCEIHFHEINNKMVECKKAQPKEVM 190
           GF FVTF   D V+K      H++N + VE KKAQ K  M
Sbjct: 284 GFCFVTFGDHDSVDKAVLKKRHDLNGRQVEVKKAQSKNDM 165

 Score = 67.4 bits (163), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 30/75 (40%), Positives = 50/75 (66%)
 Frame = -2

Query: 21  KMFIGGLSWQTTQEGLREYFGQFGEVKECLVMRDPLTKRSRGFGFVTFMDQAGVDKVLAQ 80
           KMF+GG+   TT++ +R+ F +FGE+    +++D  T ++RGF FVTF D   VDK + +
Sbjct: 407 KMFVGGVKEDTTEDMIRDTFNEFGEITGVDLIQDKGTGKNRGFCFVTFGDHDSVDKAVLK 228

Query: 81  SRHELDSKTIDPKVA 95
            RH+L+ + ++ K A
Sbjct: 227 KRHDLNGRQVEVKKA 183
>17681
          Length = 964

 Score = 68.2 bits (165), Expect = 5e-12,   Method: Compositional matrix adjust.
 Identities = 47/203 (23%), Positives = 87/203 (42%), Gaps = 43/203 (21%)
 Frame = +2

Query: 22  MFIGGLSWQTTQEGLREYFGQFGEVKECLVMRDPLTKRSRGFGFVTFMDQAGVDKVL-AQ 80
           +F+G LS +   E LRE F  FGE+  C ++RDP T +S+G+ FV+F+ +A  +  + A 
Sbjct: 38  IFVGDLSPEIETETLREAFAPFGEISNCRIVRDPQTMKSKGYAFVSFVKKAEAENAIQAM 217

Query: 81  SRHELDSKTIDPKVAFPRRAQPKMVTRTKK------------------------------ 110
           +   + S++I    +  +   P+  +++                                
Sbjct: 218 NGQWIGSRSIRTNWSTRKLPPPRESSKSGGQGGGMGGMGGCGGGAGNGIKNNQRHTFEEV 397

Query: 111 ----------IFVGGLSVNTTVEDVKH-YFEQFGKVDDAMLMFDKTTNRHRGFGFVTFES 159
                     ++ GG   N   +++ H +F QFG + D  +  DK      GF F+ F +
Sbjct: 398 YNQSSPTNTTVYCGGFPPNVISDELMHKHFMQFGPIQDVRVFKDK------GFAFIKFVT 559

Query: 160 EDIVEKVCE-IHFHEINNKMVEC 181
           ++   +  E  H  E++   V+C
Sbjct: 560 KEAAARAIEHTHISEVHGNHVKC 628
>24983
          Length = 433

 Score = 66.2 bits (160), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 28/74 (37%), Positives = 44/74 (59%)
 Frame = -2

Query: 23  FIGGLSWQTTQEGLREYFGQFGEVKECLVMRDPLTKRSRGFGFVTFMDQAGVDKVLAQSR 82
            +GGL + TT   LREYF +FG++ E +V+ D  T +SRG+GFVT  D+ G D+      
Sbjct: 306 LLGGLPYHTTDHSLREYFDKFGDIDEAVVITDRQTGKSRGYGFVTMADRTGADRACKDPN 127

Query: 83  HELDSKTIDPKVAF 96
             +D +  +  +A+
Sbjct: 126 PIIDGRKANVNLAY 85

 Score = 53.1 bits (126), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 23/74 (31%), Positives = 44/74 (59%)
 Frame = -2

Query: 112 FVGGLSVNTTVEDVKHYFEQFGKVDDAMLMFDKTTNRHRGFGFVTFESEDIVEKVCEIHF 171
            +GGL  +TT   ++ YF++FG +D+A+++ D+ T + RG+GFVT       ++ C+   
Sbjct: 306 LLGGLPYHTTDHSLREYFDKFGDIDEAVVITDRQTGKSRGYGFVTMADRTGADRACKDP- 130

Query: 172 HEINNKMVECKKAQ 185
               N +++ +KA 
Sbjct: 129 ----NPIIDGRKAN 100
>10194
          Length = 1278

 Score = 58.5 bits (140), Expect = 4e-09,   Method: Compositional matrix adjust.
 Identities = 42/183 (22%), Positives = 86/183 (46%), Gaps = 20/183 (10%)
 Frame = -3

Query: 22  MFIGGLSWQTTQEGLREYFGQFGEVKE----CLVMRDPLTKR-----SRGF--------G 64
           +F+G +  +T ++ L   F QFG+++     C  + DP TK+     ++ F         
Sbjct: 706 VFVGNVPLKTDKKKLARLFKQFGKIENVRFRCAPVGDPTTKKRVAVITKDFHEKRHNISA 527

Query: 65  FVTFMDQAGVDKVLAQSRHELDSKTIDPKVAFPRRAQPKMVTRTKKIFVGGLSVNTTVED 124
           ++ F +     + L  + H +D   +  +V   + +   +  R+  +FVG L  +   E 
Sbjct: 526 YICFKEDEAAKQALTLNGHVIDG--LHLRVDSAKLSLKNLDKRS--VFVGNLPFDIEEES 359

Query: 125 VKHYFEQFGKVDDAMLMFDKTTNRHRGFGFVTFESEDIVEKVCEIHFHEINNKMV---EC 181
           V+ +FE  G V++  ++ D+ TN  +G  ++ F+S D V    +++  E+  + +    C
Sbjct: 358 VRSHFEDCGDVENIRVVRDRKTNLGKGICYILFKSADSVSLALKLNNSELEKRQIRVQRC 179

Query: 182 KKA 184
           K A
Sbjct: 178 KDA 170

 Score = 34.7 bits (78), Expect = 0.065,   Method: Compositional matrix adjust.
 Identities = 19/96 (19%), Positives = 43/96 (44%), Gaps = 17/96 (17%)
 Frame = -3

Query: 97  PRRAQPKMVTRTKKIFVGGLSVNTTVEDVKHYFEQFGKVDD-----------------AM 139
           PRR + +     + +FVG + + T  + +   F+QFGK+++                 A+
Sbjct: 748 PRRDRLQRANEKRTVFVGNVPLKTDKKKLARLFKQFGKIENVRFRCAPVGDPTTKKRVAV 569

Query: 140 LMFDKTTNRHRGFGFVTFESEDIVEKVCEIHFHEIN 175
           +  D    RH    ++ F+ ++  ++   ++ H I+
Sbjct: 568 ITKDFHEKRHNISAYICFKEDEAAKQALTLNGHVID 461
>23655
          Length = 929

 Score = 39.3 bits (90), Expect(2) = 5e-08,   Method: Compositional matrix adjust.
 Identities = 19/43 (44%), Positives = 25/43 (58%)
 Frame = -3

Query: 148 RHRGFGFVTFESEDIVEKVCEIHFHEINNKMVECKKAQPKEVM 190
           + +GF FVTF   D V+K      H++N + VE KKAQ K  M
Sbjct: 789 QEQGFCFVTFGDHDSVDKAVLKKRHDLNGRQVEVKKAQSKNDM 661

 Score = 35.0 bits (79), Expect(2) = 5e-08,   Method: Compositional matrix adjust.
 Identities = 16/44 (36%), Positives = 29/44 (65%)
 Frame = -1

Query: 109 KKIFVGGLSVNTTVEDVKHYFEQFGKVDDAMLMFDKTTNRHRGF 152
           +K+FVGG+  +TT + ++  F +FG++    L+ DK T ++R F
Sbjct: 905 EKMFVGGVKEDTTEDMIRDTFNEFGEITGVDLIQDKGTGKNRDF 774

 Score = 39.3 bits (90), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 16/43 (37%), Positives = 29/43 (67%)
 Frame = -1

Query: 21  KMFIGGLSWQTTQEGLREYFGQFGEVKECLVMRDPLTKRSRGF 63
           KMF+GG+   TT++ +R+ F +FGE+    +++D  T ++R F
Sbjct: 902 KMFVGGVKEDTTEDMIRDTFNEFGEITGVDLIQDKGTGKNRDF 774

 Score = 35.8 bits (81), Expect = 0.028,   Method: Compositional matrix adjust.
 Identities = 17/44 (38%), Positives = 27/44 (61%), Gaps = 2/44 (4%)
 Frame = -3

Query: 54  DPLTK--RSRGFGFVTFMDQAGVDKVLAQSRHELDSKTIDPKVA 95
           DP  +  + +GF FVTF D   VDK + + RH+L+ + ++ K A
Sbjct: 810 DPRQRHWQEQGFCFVTFGDHDSVDKAVLKKRHDLNGRQVEVKKA 679
>16427
          Length = 1313

 Score = 54.3 bits (129), Expect = 8e-08,   Method: Compositional matrix adjust.
 Identities = 25/72 (34%), Positives = 43/72 (59%)
 Frame = +1

Query: 19  PCKMFIGGLSWQTTQEGLREYFGQFGEVKECLVMRDPLTKRSRGFGFVTFMDQAGVDKVL 78
           P K+F+GGL+ +  ++ L   F +FG + E +V+RD + + SRGFGFVT+ +    ++ +
Sbjct: 133 PGKLFVGGLAEEIDEKVLEREFSKFGRITESMVIRDKVRQVSRGFGFVTYENPMDAEEAV 312

Query: 79  AQSRHELDSKTI 90
                 +D K I
Sbjct: 313 KH----MDGKEI 336

 Score = 52.4 bits (124), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 28/79 (35%), Positives = 45/79 (56%), Gaps = 1/79 (1%)
 Frame = +1

Query: 107 RTKKIFVGGLSVNTTVEDVKHYFEQFGKVDDAMLMFDKTTNRHRGFGFVTFESE-DIVEK 165
           R  K+FVGGL+     + ++  F +FG++ ++M++ DK     RGFGFVT+E+  D  E 
Sbjct: 130 RPGKLFVGGLAEEIDEKVLEREFSKFGRITESMVIRDKVRQVSRGFGFVTYENPMDAEEA 309

Query: 166 VCEIHFHEINNKMVECKKA 184
           V  +   EI  K +  + A
Sbjct: 310 VKHMDGKEILGKKLHVEDA 366
>02343
          Length = 1715

 Score = 52.4 bits (124), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 41/165 (24%), Positives = 71/165 (43%)
 Frame = -2

Query: 16   PHDPCKMFIGGLSWQTTQEGLREYFGQFGEVKECLVMRDPLTKRSRGFGFVTFMDQAGVD 75
            P     ++I GLS  TT + L      FG +     + D  T + +G+GFV F D  G  
Sbjct: 1276 PLSKTNLYIRGLSPNTTDKDLVNLCQHFGTITSTKAIIDQTTNKCKGYGFVDF-DAPGAA 1100

Query: 76   KVLAQSRHELDSKTIDPKVAFPRRAQPKMVTRTKKIFVGGLSVNTTVEDVKHYFEQFGKV 135
            +   Q+   L ++ I  ++A  +   P        +++  L ++ T + ++  F+ +G V
Sbjct: 1099 ERAVQA---LQAQGIQAQMAKQQEQDP------TNLYIANLPLHFTEKHLEGLFKDYGTV 947

Query: 136  DDAMLMFDKTTNRHRGFGFVTFESEDIVEKVCEIHFHEINNKMVE 180
                ++  K     R  GF   ES D     C+   +  NNKM+ 
Sbjct: 946  ISTRIL-RKPDGISRCVGFARMESRD----KCDTVINTFNNKMIS 827
>00302
          Length = 927

 Score = 51.2 bits (121), Expect = 7e-07,   Method: Compositional matrix adjust.
 Identities = 38/101 (37%), Positives = 52/101 (51%), Gaps = 4/101 (3%)
 Frame = -1

Query: 18  DPCKMF-IGGLSWQTTQEGLREYFGQFGEVKECLVMRDPLTKRSRGFGFVTFMDQAGVDK 76
           DP +   I GLS  T + GLRE FG++G + E  V+ D  T RSRGF FV F  ++  D 
Sbjct: 474 DPNRCLGIFGLSLYTQERGLREVFGRYGHISEVQVVYDRQTGRSRGFAFVYF--KSSEDA 301

Query: 77  VLAQSRH---ELDSKTIDPKVAFPRRAQPKMVTRTKKIFVG 114
             A+ R    E+D + I    +   RA     T T  I++G
Sbjct: 300 HEAKDRCNGIEIDGRKIRVDFSITERAH----TPTPGIYLG 190

 Score = 43.9 bits (102), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 31/115 (26%), Positives = 53/115 (46%), Gaps = 1/115 (0%)
 Frame = -1

Query: 80  QSRHELDSKTIDPKVAFPRRAQPKMVTRTKKIFVGGLSVNTTVEDVKHYFEQFGKVDDAM 139
           + RH+ D +  DP              R   IF  GLS+ T    ++  F ++G + +  
Sbjct: 507 RKRHQGDRENPDP-------------NRCLGIF--GLSLYTQERGLREVFGRYGHISEVQ 373

Query: 140 LMFDKTTNRHRGFGFVTFE-SEDIVEKVCEIHFHEINNKMVECKKAQPKEVMSPT 193
           +++D+ T R RGF FV F+ SED  E     +  EI+ + +    +  +   +PT
Sbjct: 372 VVYDRQTGRSRGFAFVYFKSSEDAHEAKDRCNGIEIDGRKIRVDFSITERAHTPT 208
>05273
          Length = 1009

 Score = 50.4 bits (119), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 21/41 (51%), Positives = 29/41 (70%)
 Frame = -1

Query: 31  TTQEGLREYFGQFGEVKECLVMRDPLTKRSRGFGFVTFMDQ 71
           TT   LREYF +FG++ E +V+ D  T +SRG+GFVT  D+
Sbjct: 166 TTDHSLREYFDKFGDIDEAVVITDRQTGKSRGYGFVTMADR 44

 Score = 43.5 bits (101), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 16/40 (40%), Positives = 29/40 (72%)
 Frame = -1

Query: 118 VNTTVEDVKHYFEQFGKVDDAMLMFDKTTNRHRGFGFVTF 157
           + TT   ++ YF++FG +D+A+++ D+ T + RG+GFVT 
Sbjct: 172 IITTDHSLREYFDKFGDIDEAVVITDRQTGKSRGYGFVTM 53
>09968
          Length = 2913

 Score = 46.2 bits (108), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 29/86 (33%), Positives = 44/86 (51%), Gaps = 2/86 (2%)
 Frame = -1

Query: 103  KMVTRTKKIFVGGLSVNTTVEDVKHYFEQFGKVDDAMLMFDKTTNRHRGFGFVTFESEDI 162
            K  T  + ++V GLS +T   D+K  F + GKV  A ++ +  +     FGFVT  S D 
Sbjct: 1410 KATTSIRNLWVSGLSSSTRATDLKSLFGKHGKVIGAKVVTNTRSPGRLCFGFVTMASADE 1231

Query: 163  VEKVCEIHFH--EINNKMVECKKAQP 186
              K C  H H  E++ KM+  ++  P
Sbjct: 1230 TTK-CIQHLHRTELHGKMISVERFSP 1156

 Score = 28.9 bits (63), Expect = 3.5,   Method: Compositional matrix adjust.
 Identities = 21/70 (30%), Positives = 31/70 (44%), Gaps = 1/70 (1%)
 Frame = -1

Query: 22   MFIGGLSWQTTQEGLREYFGQFGEVKECLVMRDPLTKRSRGFGFVTFMDQAGVDKVLAQ- 80
            +++ GLS  T    L+  FG+ G+V    V+ +  +     FGFVT        K +   
Sbjct: 1386 LWVSGLSSSTRATDLKSLFGKHGKVIGAKVVTNTRSPGRLCFGFVTMASADETTKCIQHL 1207

Query: 81   SRHELDSKTI 90
             R EL  K I
Sbjct: 1206 HRTELHGKMI 1177
>17775
          Length = 1282

 Score = 46.2 bits (108), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 42/150 (28%), Positives = 69/150 (46%), Gaps = 20/150 (13%)
 Frame = -2

Query: 59  RSRGFGFVTFMDQAGVDKVLAQSRHELDSKTIDPKVAFPRRAQPK------MVTRTKKI- 111
           +SRGFGFV+F +  G +K +     E++   +  ++ +  RAQ +      +  R +KI 
Sbjct: 537 KSRGFGFVSFEEPEGAEKAV----DEINGTEVSGRIIYCGRAQKRAERQAELKERFEKIK 370

Query: 112 ------------FVGGLSVNTTVEDVKHYFEQFGKVDDAMLMFDKTTNRHRGFGFVTFES 159
                       +V  L  +   E ++  F  FG +  A +M +    R +GFGFV F S
Sbjct: 369 LERINRYQGVNLYVKNLDDSIDDERLRKEFSNFGTITSAKIMTE--GGRSKGFGFVCFSS 196

Query: 160 -EDIVEKVCEIHFHEINNKMVECKKAQPKE 188
            E+  + V E++   I  K +    AQ KE
Sbjct: 195 PEEATKAVTEMNGRIIVAKPLYVALAQRKE 106
>28652
          Length = 918

 Score = 43.5 bits (101), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 35/159 (22%), Positives = 73/159 (45%), Gaps = 5/159 (3%)
 Frame = -2

Query: 6   PQPGLASPDSPHDPCKMFIGGLSWQTTQEGLREYFGQFGEVKECLVMRDPLTKRSRGFGF 65
           P PG   P  P    ++F G +     ++ L   F   G + +  +M DP++  +RG+ F
Sbjct: 770 PPPGWTDP-QPGSGHEVFCGKIPRDIFEDELIPLFEDCGTIWDLRLMMDPVSNLNRGYCF 594

Query: 66  VTF-MDQAGVDKVLAQSRHEL-DSKTIDPKVAFPRRAQPKMVTRTKKIFVGGLSVNTTVE 123
           VT+   +A  + V     +E+   K +   ++ P            ++FVG +  + T E
Sbjct: 593 VTYTTKEAAAEAVKQHDGYEIRKGKKLKVNISIP----------NLRLFVGNIPKSKTKE 444

Query: 124 DVKHYFEQFGKVDDAMLMFDKTTN---RHRGFGFVTFES 159
           ++   FE+  +    ++++    N   ++RGF F+ +++
Sbjct: 443 EILKEFEKHSEGLMDVIVYGSADNPKLKNRGFAFLEYDT 327

 Score = 38.9 bits (89), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 32/126 (25%), Positives = 58/126 (46%), Gaps = 4/126 (3%)
 Frame = -2

Query: 49  CLVMRDPLTKRSRGFGFVTFMDQAGVDKVLAQSRHELDSKTIDPKVAFP----RRAQPKM 104
           C  M++  TK + G       D+A +  +L ++ +ELD  T   K   P       QP  
Sbjct: 914 CGKMKNLKTKGAGGGAQTKKPDEAKIQAILKRTGYELDVTTGQRKYGGPPPGWTDPQP-- 741

Query: 105 VTRTKKIFVGGLSVNTTVEDVKHYFEQFGKVDDAMLMFDKTTNRHRGFGFVTFESEDIVE 164
                ++F G +  +   +++   FE  G + D  LM D  +N +RG+ FVT+ +++   
Sbjct: 740 -GSGHEVFCGKIPRDIFEDELIPLFEDCGTIWDLRLMMDPVSNLNRGYCFVTYTTKEAAA 564

Query: 165 KVCEIH 170
           +  + H
Sbjct: 563 EAVKQH 546
>00556
          Length = 2189

 Score = 43.1 bits (100), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 25/75 (33%), Positives = 41/75 (54%), Gaps = 3/75 (4%)
 Frame = +3

Query: 8   PGLAS---PDSPHDPCKMFIGGLSWQTTQEGLREYFGQFGEVKECLVMRDPLTKRSRGFG 64
           PG+ S    DS H   K+F+GGL    +++ ++E    FG +K   ++RD  T  S+GF 
Sbjct: 723 PGVVSTVVQDSDH---KIFMGGLPSYLSEDQMKELLLSFGPLKSFNLVRDNATGLSKGFA 893

Query: 65  FVTFMDQAGVDKVLA 79
           F  ++D +  D+  A
Sbjct: 894 FCEYLDPSVTDQACA 938

 Score = 37.4 bits (85), Expect = 0.011,   Method: Compositional matrix adjust.
 Identities = 33/168 (19%), Positives = 65/168 (38%), Gaps = 21/168 (12%)
 Frame = +3

Query: 21  KMFIGGLSWQTTQEGLREYFGQFGEVKECLVMR-DPLT----KRSRGFGFVTFMDQAGVD 75
           ++++G + +  T+E + ++F    ++        DP+        + F F+         
Sbjct: 432 RLYVGNIPFGVTEESMMDFFNHQMKITGLAQAEGDPVIAVHINLDKNFAFLELRSVDETT 611

Query: 76  KVLA-----------QSRHELDSKTIDPKVAFPRRAQPKMVTRT-----KKIFVGGLSVN 119
           + LA           + R   D K +      P +A P +V+        KIF+GGL   
Sbjct: 612 QALAFDGIAYETQPLKIRRPSDYKPLPGLSENPTQAVPGVVSTVVQDSDHKIFMGGLPSY 791

Query: 120 TTVEDVKHYFEQFGKVDDAMLMFDKTTNRHRGFGFVTFESEDIVEKVC 167
            + + +K     FG +    L+ D  T   +GF F  +    + ++ C
Sbjct: 792 LSEDQMKELLLSFGPLKSFNLVRDNATGLSKGFAFCEYLDPSVTDQAC 935
>30672
          Length = 877

 Score = 43.1 bits (100), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 20/62 (32%), Positives = 35/62 (56%), Gaps = 2/62 (3%)
 Frame = +3

Query: 20  CKMFIGGLSWQTTQEGLREYFGQFGEVKECLVMRDPLTK--RSRGFGFVTFMDQAGVDKV 77
           C++ I  L+++  +  +R +FG+FG + E  +   PL +  RSRGF FV F +     K 
Sbjct: 405 CRLIIRNLAFKCKEADIRSHFGKFGTISEVTI---PLKQGDRSRGFAFVQFTEVKAAQKA 575

Query: 78  LA 79
           ++
Sbjct: 576 IS 581

 Score = 39.3 bits (90), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 40/179 (22%), Positives = 67/179 (37%), Gaps = 43/179 (24%)
 Frame = +3

Query: 22  MFIGGLSWQTTQEGLREYFGQFGEVKECLVMRDPLTKRSRGFGFVTF------------- 68
           +F+  L ++T+ E L E F Q G +K   V+      + RGFG+V F             
Sbjct: 18  LFVRNLPFETSNEKLLEAFEQVGPLKTAFVVAGKEPGKCRGFGYVQFSMLEDAIKAKDTV 197

Query: 69  -----------------------------MDQAGVDKVLAQSRHELDSKTIDPKVAFPRR 99
                                         D  G+ K L       D +  +PK    + 
Sbjct: 198 THCSGRKISLSFADTKKSWKTKQKGGTETSDALGLGKKLPSQTAVTDGEP-NPKPEKKKT 374

Query: 100 AQPKM-VTRTKKIFVGGLSVNTTVEDVKHYFEQFGKVDDAMLMFDKTTNRHRGFGFVTF 157
            QPK  + +  ++ +  L+      D++ +F +FG + +  +   K  +R RGF FV F
Sbjct: 375 KQPKQELGKRCRLIIRNLAFKCKEADIRSHFGKFGTISEVTIPL-KQGDRSRGFAFVQF 548

 Score = 34.3 bits (77), Expect = 0.072,   Method: Compositional matrix adjust.
 Identities = 18/51 (35%), Positives = 28/51 (54%)
 Frame = +3

Query: 107 RTKKIFVGGLSVNTTVEDVKHYFEQFGKVDDAMLMFDKTTNRHRGFGFVTF 157
           ++K +FV  L   T+ E +   FEQ G +  A ++  K   + RGFG+V F
Sbjct: 6   QSKTLFVRNLPFETSNEKLLEAFEQVGPLKTAFVVAGKEPGKCRGFGYVQF 158
>13457
          Length = 4857

 Score = 43.1 bits (100), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 18/48 (37%), Positives = 31/48 (64%)
 Frame = -1

Query: 21   KMFIGGLSWQTTQEGLREYFGQFGEVKECLVMRDPLTKRSRGFGFVTF 68
            K+F+G L+ Q T+E +R+ F  +G ++EC ++RD     S+G  FV +
Sbjct: 3405 KLFVGMLNKQQTEEDVRQLFHPYGAIEECTILRDQ-NGNSKGCAFVKY 3265

 Score = 40.4 bits (93), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 20/62 (32%), Positives = 35/62 (56%), Gaps = 1/62 (1%)
 Frame = -1

Query: 99   RAQPKM-VTRTKKIFVGGLSVNTTVEDVKHYFEQFGKVDDAMLMFDKTTNRHRGFGFVTF 157
            R  PKM +   +K+FVG L+   T EDV+  F  +G +++  ++ D+  N  +G  FV +
Sbjct: 3441 RLTPKMTIGEDRKLFVGMLNKQQTEEDVRQLFHPYGAIEECTILRDQNGN-SKGCAFVKY 3265

Query: 158  ES 159
             +
Sbjct: 3264 ST 3259
>32733
          Length = 709

 Score = 42.4 bits (98), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 21/59 (35%), Positives = 30/59 (50%)
 Frame = +1

Query: 101 QPKMVTRTKKIFVGGLSVNTTVEDVKHYFEQFGKVDDAMLMFDKTTNRHRGFGFVTFES 159
           +PK    T +   G LS   +  DV+  FE FG +DD  ++ D +    RG  F+TF S
Sbjct: 442 EPKCSMWTDRCLWGMLSKKLSENDVRMLFESFGSIDDCTVLRD-SNGTSRGCAFITFAS 615
>02502
          Length = 1557

 Score = 41.6 bits (96), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 24/91 (26%), Positives = 43/91 (47%), Gaps = 1/91 (1%)
 Frame = -3

Query: 111  IFVGGLSVNTTVEDVKHYFEQFGKVDDAMLMFDKTTNRHRGFGFVTFESEDIV-EKVCEI 169
            ++ GG++   T E + + F+ FG + +  +  DK      GF F+ F ++D     +C I
Sbjct: 1435 VYCGGVNNGLTEELMHNTFKDFGSILEVRIFKDK------GFAFIRFNNKDAATNAICTI 1274

Query: 170  HFHEINNKMVECKKAQPKEVMSPTGSARGRS 200
            H   IN+++V C   +      P  +  G S
Sbjct: 1273 HGTVINDQVVRCSWGKESNEAPPGQNPSGAS 1181
>31310
          Length = 469

 Score = 41.2 bits (95), Expect = 6e-04,   Method: Compositional matrix adjust.
 Identities = 12/49 (24%), Positives = 32/49 (65%)
 Frame = -3

Query: 20  CKMFIGGLSWQTTQEGLREYFGQFGEVKECLVMRDPLTKRSRGFGFVTF 68
           C++++G ++++  ++ +++ F  FG +K   +  DP+T + +GF F+ +
Sbjct: 323 CRIYVGSINFEIREDTIKQAFLPFGPIKSVNLSWDPITNKHKGFSFIEY 177

 Score = 41.2 bits (95), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 18/70 (25%), Positives = 37/70 (52%)
 Frame = -3

Query: 110 KIFVGGLSVNTTVEDVKHYFEQFGKVDDAMLMFDKTTNRHRGFGFVTFESEDIVEKVCEI 169
           +I+VG ++     + +K  F  FG +    L +D  TN+H+GF F+ ++    V +  ++
Sbjct: 320 RIYVGSINFEIREDTIKQAFLPFGPIKSVNLSWDPITNKHKGFSFIEYD----VPEAAQL 153

Query: 170 HFHEINNKMV 179
              ++N  M+
Sbjct: 152 ALEQMNGVMI 123
>08958
          Length = 680

 Score = 41.2 bits (95), Expect = 6e-04,   Method: Compositional matrix adjust.
 Identities = 36/140 (25%), Positives = 59/140 (42%), Gaps = 2/140 (1%)
 Frame = +2

Query: 20  CKMFIGGLSWQTTQEGLREYFGQFGEVKECLVMRDPLTKRSRGFGFVTFMDQAGVDKVLA 79
           C++F+G L+   +++  ++ F  FGEV E  V         RGFGF+             
Sbjct: 68  CRLFVGNLTPDVSEDDFKKLFSPFGEVSEAYV------NSGRGFGFIRL----------- 196

Query: 80  QSRH--ELDSKTIDPKVAFPRRAQPKMVTRTKKIFVGGLSVNTTVEDVKHYFEQFGKVDD 137
             RH  E     +D      R  + +  T    + V  L    + E ++  F QFG ++ 
Sbjct: 197 DYRHNAEAAKAALDGLQRKGRSLRVRYATHGAALKVKNLHPYVSNELLEQAFTQFGDLER 376

Query: 138 AMLMFDKTTNRHRGFGFVTF 157
           A+++ D+   R  G G V F
Sbjct: 377 AIVIVDE-RGRSTGEGVVEF 433

 Score = 33.9 bits (76), Expect = 0.11,   Method: Compositional matrix adjust.
 Identities = 17/49 (34%), Positives = 28/49 (57%)
 Frame = +2

Query: 110 KIFVGGLSVNTTVEDVKHYFEQFGKVDDAMLMFDKTTNRHRGFGFVTFE 158
           ++FVG L+ + + +D K  F  FG+V +A +      N  RGFGF+  +
Sbjct: 71  RLFVGNLTPDVSEDDFKKLFSPFGEVSEAYV------NSGRGFGFIRLD 199
>00029
          Length = 2204

 Score = 40.4 bits (93), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 20/61 (32%), Positives = 30/61 (49%)
 Frame = -3

Query: 20   CKMFIGGLSWQTTQEGLREYFGQFGEVKECLVMRDPLTKRSRGFGFVTFMDQAGVDKVLA 79
             K+FIG L   T  E LR  F ++G V EC V+++        FGFV  + +   D  ++
Sbjct: 2136 IKIFIGNLGDDTDPEELRALFEKYGSVAECDVLKN--------FGFVHMVKKGEADDAIS 1981

Query: 80   Q 80
             
Sbjct: 1980 N 1978
>11126
          Length = 1061

 Score = 38.9 bits (89), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 18/68 (26%), Positives = 36/68 (52%)
 Frame = -3

Query: 96  FPRRAQPKMVTRTKKIFVGGLSVNTTVEDVKHYFEQFGKVDDAMLMFDKTTNRHRGFGFV 155
           FP + + K+    + ++VG +    T E+++ +F   G V+   ++ DK +   +GF +V
Sbjct: 666 FPSQ-EDKIEADLRSVYVGNVDYGATAEELEQHFHGCGSVNRVTILCDKYSGHPKGFAYV 490

Query: 156 TFESEDIV 163
            F  +D V
Sbjct: 489 EFADKDSV 466
>13822
          Length = 963

 Score = 37.7 bits (86), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 20/93 (21%), Positives = 48/93 (51%)
 Frame = -1

Query: 15  SPHDPCKMFIGGLSWQTTQEGLREYFGQFGEVKECLVMRDPLTKRSRGFGFVTFMDQAGV 74
           SP  P ++ +  + ++  +  LR+  G FG + +  ++ +   + S+GFGFVTF   A  
Sbjct: 357 SPEGPKRLHVSNIPFRFREADLRQLLGPFGTILDVEIIFN--ERGSKGFGFVTFAHSAEA 184

Query: 75  DKVLAQSRHELDSKTIDPKVAFPRRAQPKMVTR 107
           ++    +R +++   ++ +      A  +++T+
Sbjct: 183 ER----ARDKMNGTVVEGRKIEVNNATARVMTK 97

 Score = 31.6 bits (70), Expect = 0.54,   Method: Compositional matrix adjust.
 Identities = 19/77 (24%), Positives = 38/77 (49%)
 Frame = -1

Query: 109 KKIFVGGLSVNTTVEDVKHYFEQFGKVDDAMLMFDKTTNRHRGFGFVTFESEDIVEKVCE 168
           K++ V  +       D++     FG + D  ++F++  ++  GFGFVTF      E+  +
Sbjct: 342 KRLHVSNIPFRFREADLRQLLGPFGTILDVEIIFNERGSK--GFGFVTFAHSAEAERARD 169

Query: 169 IHFHEINNKMVECKKAQ 185
               ++N  +VE +K +
Sbjct: 168 ----KMNGTVVEGRKIE 130
>23720
          Length = 739

 Score = 37.7 bits (86), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 42/206 (20%), Positives = 78/206 (37%), Gaps = 39/206 (18%)
 Frame = -1

Query: 21  KMFIGGLSWQTTQEGLREYFGQFGEVKECLVMRDPLTKRSRGFGFVTFMDQAGVDKVLAQ 80
           +++IG L +Q  ++ +  +F  +G V + ++          G+GFV F D    D  +  
Sbjct: 682 RVYIGRLPYQAREKDIERFFRGYGRVNDIML--------KNGYGFVEFEDFRDADDAV-- 533

Query: 81  SRHELDSKTIDPKVAFPRRAQPKMV----------------------------------- 105
             +EL+ K +  +      A+                                       
Sbjct: 532 --YELNGKDLCGERVIIEHARGTSRGGGGGGGGRDRDRDGGGYYDRGGSSRRSGWGDKYG 359

Query: 106 --TRTK-KIFVGGLSVNTTVEDVKHYFEQFGKVDDAMLMFDKTTNRHRGFGFVTFE-SED 161
             TRT  ++ V  LS   + +D+K Y  Q G+V      +     RHR  G + F  S D
Sbjct: 358 PPTRTDYRLVVENLSSRVSWQDLKDYMRQAGEV-----TYADAHKRHRNEGIIEFATSSD 194

Query: 162 IVEKVCEIHFHEINNKMVECKKAQPK 187
           +   + ++   EIN + ++  + +PK
Sbjct: 193 LKNALDKLDNTEINGRKIKLVEDRPK 116
>04988
          Length = 705

 Score = 37.0 bits (84), Expect = 0.012,   Method: Compositional matrix adjust.
 Identities = 44/212 (20%), Positives = 79/212 (37%), Gaps = 45/212 (21%)
 Frame = -3

Query: 21  KMFIGGLSWQTTQEGLREYFGQFGEVKECLVMRDPLTKRSRGFGFVTFMDQAGVDKVLAQ 80
           +++IG L +Q  ++ +  +F  +G V + ++          G+GFV F D    D  +  
Sbjct: 649 RVYIGRLPYQAREKDIERFFRGYGRVNDIML--------KNGYGFVEFEDFRDADDAV-- 500

Query: 81  SRHELDSKTIDPKVAF-------------------------------------------P 97
             +EL+ K +  +                                              P
Sbjct: 499 --YELNGKDLCGERVIIEHARGTSRGGGGGGGGRDRDRDGGGYYDRGGSSRRSGWGDKVP 326

Query: 98  RRAQPKMVTRTK-KIFVGGLSVNTTVEDVKHYFEQFGKVDDAMLMFDKTTNRHRGFGFVT 156
           R   P   TRT  ++ V  LS   + +D+K Y  Q G+V      +     RHR  G + 
Sbjct: 325 RYGPP---TRTDYRLVVENLSSRVSWQDLKDYMRQAGEV-----TYADAHKRHRNEGIIE 170

Query: 157 FE-SEDIVEKVCEIHFHEINNKMVECKKAQPK 187
           F  S D+   + ++   EIN + ++  + +PK
Sbjct: 169 FATSSDLKNALDKLDNTEINGRKIKLVEDRPK 74
>25691
          Length = 768

 Score = 36.6 bits (83), Expect = 0.017,   Method: Compositional matrix adjust.
 Identities = 18/72 (25%), Positives = 32/72 (44%)
 Frame = -2

Query: 21  KMFIGGLSWQTTQEGLREYFGQFGEVKECLVMRDPLTKRSRGFGFVTFMDQAGVDKVLAQ 80
            ++I GL    TQ  L   F   G +    ++ D  T  S+G GF+ F  +   ++ + +
Sbjct: 257 NLYISGLPKSLTQLDLENLFTDCGNIITSRILYDQTTGLSKGVGFIRFDQRIEAERAIQK 78

Query: 81  SRHELDSKTIDP 92
             + +    IDP
Sbjct: 77  LNNHIPDGCIDP 42
>25950
          Length = 417

 Score = 35.4 bits (80), Expect = 0.032,   Method: Compositional matrix adjust.
 Identities = 15/68 (22%), Positives = 35/68 (51%)
 Frame = -2

Query: 97  PRRAQPKMVTRTKKIFVGGLSVNTTVEDVKHYFEQFGKVDDAMLMFDKTTNRHRGFGFVT 156
           P   + K    T+ ++VG +    + E+++ +F   G ++   ++ +K     +GF ++ 
Sbjct: 317 PLSLEEKQEIDTRSVYVGNVDYGASAEELEAHFHGCGTINRVTILCNKADGHPKGFAYIE 138

Query: 157 FESEDIVE 164
           F S++ VE
Sbjct: 137 FGSKEYVE 114
>35180
          Length = 2181

 Score = 33.9 bits (76), Expect = 0.11,   Method: Compositional matrix adjust.
 Identities = 17/58 (29%), Positives = 33/58 (56%), Gaps = 3/58 (5%)
 Frame = -2

Query: 108 TKKIFVGGLSVNTTVEDVKHYFEQFGKVDDAMLMFDKTTNRHRGFGFVTF---ESEDI 162
           ++ ++V G   + T++ +  +FEQ GK+D  ++  ++     +G  FVTF   E ED+
Sbjct: 263 SRSVYVKGFPEDITLDTLMEFFEQHGKIDTILMRRNRPDKNFKGSVFVTFSNKEEEDV 90

 Score = 30.4 bits (67), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 19/69 (27%), Positives = 34/69 (49%)
 Frame = -2

Query: 22  MFIGGLSWQTTQEGLREYFGQFGEVKECLVMRDPLTKRSRGFGFVTFMDQAGVDKVLAQS 81
           +++ G     T + L E+F Q G++   L+ R+   K  +G  FVTF ++   D  L + 
Sbjct: 254 VYVKGFPEDITLDTLMEFFEQHGKIDTILMRRNRPDKNFKGSVFVTFSNKEEEDVFLGKD 75

Query: 82  RHELDSKTI 90
               D++ I
Sbjct: 74  VKYNDTELI 48
>28455
          Length = 573

 Score = 33.9 bits (76), Expect = 0.11,   Method: Compositional matrix adjust.
 Identities = 20/84 (23%), Positives = 42/84 (50%), Gaps = 1/84 (1%)
 Frame = -1

Query: 110 KIFVGGLSVNTTVEDVKHYFEQFGKVDDAMLMFDKTTNRHRGFGFVTFESEDIV-EKVCE 168
           K+FV  L    + E ++  F++ GKV D  L+  + +   +G  +V FE+E++  + V +
Sbjct: 537 KLFVKNLPFTCSAEALETIFKEHGKVKDVRLVTYR-SGASKGLAYVEFETEEMATQAVMK 361

Query: 169 IHFHEINNKMVECKKAQPKEVMSP 192
               ++ + M+    + P +   P
Sbjct: 360 TDGLQVGDHMISVAISNPPQRKQP 289
>39789
          Length = 361

 Score = 32.0 bits (71), Expect = 0.43,   Method: Compositional matrix adjust.
 Identities = 18/69 (26%), Positives = 30/69 (43%)
 Frame = +1

Query: 22  MFIGGLSWQTTQEGLREYFGQFGEVKECLVMRDPLTKRSRGFGFVTFMDQAGVDKVLAQS 81
           +F+G LS+ T Q  L++    F       + +   T++ RGFGFV F             
Sbjct: 94  LFVGNLSYDTDQYSLKD---AFPGATAARIAKFQDTQKPRGFGFVEFSTPDDAASAFDSG 264

Query: 82  RHELDSKTI 90
             E+D + +
Sbjct: 265 EREVDGRQV 291

 Score = 31.2 bits (69), Expect = 0.64,   Method: Compositional matrix adjust.
 Identities = 23/77 (29%), Positives = 35/77 (45%)
 Frame = +1

Query: 108 TKKIFVGGLSVNTTVEDVKHYFEQFGKVDDAMLMFDKTTNRHRGFGFVTFESEDIVEKVC 167
           T  +FVG LS +T    +K  F   G     +  F + T + RGFGFV F + D      
Sbjct: 85  TSVLFVGNLSYDTDQYSLKDAFP--GATAARIAKF-QDTQKPRGFGFVEFSTPDDAASAF 255

Query: 168 EIHFHEINNKMVECKKA 184
           +    E++ + V+   A
Sbjct: 256 DSGEREVDGRQVKLSFA 306
>11108
          Length = 493

 Score = 30.4 bits (67), Expect = 1.0,   Method: Compositional matrix adjust.
 Identities = 15/77 (19%), Positives = 39/77 (50%), Gaps = 3/77 (3%)
 Frame = -1

Query: 103 KMVTRTKKIFVGGLSVNTTVEDVKHYFEQFGKVDDAMLMFDKTTNRHRGFGFVTFESEDI 162
           +M+  + K+F+GG+  + + + +   F+ FG +       ++   + +G+ ++ FES+  
Sbjct: 310 RMLNYSPKVFLGGIPWDISEQSLIQIFKPFGSIKVEWPGKEQQAAQPKGYVYIIFESDKQ 131

Query: 163 VEKV---CEIHFHEINN 176
           V+ +   C +   +  N
Sbjct: 130 VKALLSACVLQVDDSQN 80
>19556
          Length = 917

 Score = 30.4 bits (67), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 17/46 (36%), Positives = 22/46 (47%)
 Frame = -1

Query: 23  FIGGLSWQTTQEGLREYFGQFGEVKECLVMRDPLTKRSRGFGFVTF 68
           FIGGL    T+E L E F +FG+V    +        SR F +V  
Sbjct: 821 FIGGLVKGVTEEELMEKFSRFGQVSNVDIKTRTNGIDSRTFAYVNL 684

 Score = 30.0 bits (66), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 20/68 (29%), Positives = 31/68 (45%)
 Frame = -1

Query: 109 KKIFVGGLSVNTTVEDVKHYFEQFGKVDDAMLMFDKTTNRHRGFGFVTFESEDIVEKVCE 168
           K+ F+GGL    T E++   F +FG+V +  +         R F +V   +E+   K C 
Sbjct: 830 KENFIGGLVKGVTEEELMEKFSRFGQVSNVDIKTRTNGIDSRTFAYVNLTAEENGFKKC- 654

Query: 169 IHFHEINN 176
             F   NN
Sbjct: 653 --FTAYNN 636
>30934
          Length = 809

 Score = 30.0 bits (66), Expect = 1.7,   Method: Compositional matrix adjust.
 Identities = 14/35 (40%), Positives = 21/35 (60%)
 Frame = +1

Query: 35 GLREYFGQFGEVKECLVMRDPLTKRSRGFGFVTFM 69
          G + Y  + G V +  +  DP+TK+ +GF  VTFM
Sbjct: 1  GCQRYRDKGGPVTDLDLPVDPITKKIKGFAHVTFM 105
>21869
          Length = 503

 Score = 29.6 bits (65), Expect = 1.8,   Method: Compositional matrix adjust.
 Identities = 10/32 (31%), Positives = 19/32 (59%)
 Frame = -1

Query: 16 PHDPCKMFIGGLSWQTTQEGLREYFGQFGEVK 47
          P+    + + GL W++T++ L+ YF QF   +
Sbjct: 98 PNKCSDLIVLGLPWKSTEDDLKTYFSQFWRSR 3
>33504
          Length = 282

 Score = 29.6 bits (65), Expect = 1.9,   Method: Composition-based stats.
 Identities = 17/50 (34%), Positives = 26/50 (52%), Gaps = 4/50 (8%)
 Frame = +1

Query: 9   GLASPDSPHDPCK----MFIGGLSWQTTQEGLREYFGQFGEVKECLVMRD 54
           G+    S HD  K    +FIGGL +  T+  +   F Q+GE+    ++RD
Sbjct: 124 GVVGKKSWHDEYKDSAWVFIGGLPYDLTEGDIICVFSQYGEIVNINLVRD 273

 Score = 27.7 bits (60), Expect = 6.8,   Method: Composition-based stats.
 Identities = 12/34 (35%), Positives = 21/34 (61%)
 Frame = +1

Query: 111 IFVGGLSVNTTVEDVKHYFEQFGKVDDAMLMFDK 144
           +F+GGL  + T  D+   F Q+G++ +  L+ DK
Sbjct: 175 VFIGGLPYDLTEGDIICVFSQYGEIVNINLVRDK 276
>02064
          Length = 1195

 Score = 29.6 bits (65), Expect = 1.9,   Method: Compositional matrix adjust.
 Identities = 23/78 (29%), Positives = 35/78 (44%), Gaps = 1/78 (1%)
 Frame = +1

Query: 18  DPCKMFIGGLSWQTTQEGLREYFGQFGEVKECLVMRDPLTKRSRGFGFVTF-MDQAGVDK 76
           D C + +  L +  T + LRE F + G VK   +  D    RS G G V F  +   V  
Sbjct: 73  DNCTVQVKNLPYAITWQDLRERFQEIGVVKYSEITMDK--GRSTGQGLVRFATEDDAVRA 246

Query: 77  VLAQSRHELDSKTIDPKV 94
           + +  R   + +TI  K+
Sbjct: 247 INSMDRTRYEGRTIGVKM 300
>35379
          Length = 534

 Score = 25.8 bits (55), Expect(2) = 2.4,   Method: Compositional matrix adjust.
 Identities = 7/19 (36%), Positives = 16/19 (84%)
 Frame = +1

Query: 150 RGFGFVTFESEDIVEKVCE 168
           +G+GFVTFE+++  +++ +
Sbjct: 106 KGYGFVTFENQEDADRIIK 162

 Score = 21.9 bits (45), Expect(2) = 2.4,   Method: Compositional matrix adjust.
 Identities = 7/19 (36%), Positives = 12/19 (63%)
 Frame = +2

Query: 114 GGLSVNTTVEDVKHYFEQF 132
           GG++ NT   ++K YF+  
Sbjct: 2   GGIAANTAETELKQYFQHL 58
>12096
          Length = 1585

 Score = 28.1 bits (61), Expect = 6.3,   Method: Compositional matrix adjust.
 Identities = 19/56 (33%), Positives = 28/56 (50%), Gaps = 1/56 (1%)
 Frame = -3

Query: 111  IFVGGLSVNTTVE-DVKHYFEQFGKVDDAMLMFDKTTNRHRGFGFVTFESEDIVEK 165
            I + GLS NT VE D+     + G     +    + T   RGFGFV F+S+   ++
Sbjct: 1217 ILLRGLS-NTLVENDIIQELIRIGMPPKDVRFMRRVTGASRGFGFVEFQSQSEAQR 1053
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|82617575|ref|NP_084011.1| glutamyl-prolyl-tRNA
synthetase [Mus musculus]
         (1512 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

08695                                                                 241   2e-63
28731                                                                 227   2e-59
27596                                                                 206   8e-53
31189                                                                  77   2e-22
28739                                                                  85   2e-16
05674                                                                  80   7e-15
20405                                                                  45   3e-04
20465                                                                  38   0.024
10621                                                                  38   0.024
04150                                                                  37   0.042
23211                                                                  35   0.32 
20434                                                                  30   5.8  
>08695
          Length = 861

 Score =  241 bits (614), Expect = 2e-63,   Method: Compositional matrix adjust.
 Identities = 136/266 (51%), Positives = 161/266 (60%), Gaps = 9/266 (3%)
 Frame = +1

Query: 850  VTEAVECLLSLKAEYKEKTGKDYVPGQPPASQNSHSNPVSNAQPAG---------AEKPE 900
            +  AV+ LLSLK +YKE TGKD+ P  P A     S+P   AQPA           + PE
Sbjct: 100  IDAAVKVLLSLKKQYKEATGKDWTP--PKAG----SSPAKTAQPAAMPAVGGNAAVDSPE 261

Query: 901  AKVLFDRVACQGEVVRKLKAEKASKDQVDSAVQELLQLKAQYKSLTGIEYKPVSATGAED 960
            A  L   V  QG+ VR+LK   A+K++VD+AV++LL+LK ++K LTG +   V+  G  D
Sbjct: 262  ALALKAEVDAQGDKVRQLKTGGAAKEEVDAAVKKLLELKGKFKDLTGTD---VAGGGKRD 432

Query: 961  XXXXXXXXXXXXXXXXXXXXXXDXXXXXXXXXXXXXXXXXXXXXXXXXXXXTRLGLEAKK 1020
                                                               TRLGLEAKK
Sbjct: 433  KKAGADKNKGAGADKGKGGKNK---GAGGDGADKGSKPAKEADGAREVKKITRLGLEAKK 603

Query: 1021 EENLAEWYSQVITKSEMIEYYDVSGCYILRPWSYSIWESIKDFFDAEIKKLGVENCYFPI 1080
            EENL++WYSQVITKSEMIEYYD+SGCYILR WSYSIWE IKDFFDAEIKKLGVENCYFPI
Sbjct: 604  EENLSDWYSQVITKSEMIEYYDISGCYILRNWSYSIWEKIKDFFDAEIKKLGVENCYFPI 783

Query: 1081 FVSQAALEKEKNHIEDFAPEVAWVTR 1106
            FVS +ALE+EK HIEDFAPEVAWVT+
Sbjct: 784  FVSHSALEREKTHIEDFAPEVAWVTK 861

 Score = 69.7 bits (169), Expect = 9e-12,   Method: Compositional matrix adjust.
 Identities = 46/109 (42%), Positives = 68/109 (62%), Gaps = 8/109 (7%)
 Frame = +1

Query: 775 EDIDAAVKQLLTLKAEYKEKTGQEYKP---GNPSA-----AAVQTVSTKSSSNTVESTSL 826
           E+IDAAVK LL+LK +YKE TG+++ P   G+  A     AA+  V   ++ ++ E+ +L
Sbjct: 94  EEIDAAVKVLLSLKKQYKEATGKDWTPPKAGSSPAKTAQPAAMPAVGGNAAVDSPEALAL 273

Query: 827 YNKVAAQGEVVRKLKAEKAPKAKVTEAVECLLSLKAEYKEKTGKDYVPG 875
             +V AQG+ VR+LK   A K +V  AV+ LL LK ++K+ TG D   G
Sbjct: 274 KAEVDAQGDKVRQLKTGGAAKEEVDAAVKKLLELKGKFKDLTGTDVAGG 420

 Score = 52.4 bits (124), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 34/82 (41%), Positives = 48/82 (58%), Gaps = 3/82 (3%)
 Frame = +1

Query: 725 KKETSSAPKERPA--PAVSSTCAT-AEDSSVLYSRVAVQGDVVRELKAKKAPKEDIDAAV 781
           K  +S A   +PA  PAV    A  + ++  L + V  QGD VR+LK   A KE++DAAV
Sbjct: 178 KAGSSPAKTAQPAAMPAVGGNAAVDSPEALALKAEVDAQGDKVRQLKTGGAAKEEVDAAV 357

Query: 782 KQLLTLKAEYKEKTGQEYKPGN 803
           K+LL LK ++K+ TG +   G 
Sbjct: 358 KKLLELKGKFKDLTGTDVAGGG 423
>28731
          Length = 496

 Score =  227 bits (579), Expect = 2e-59,   Method: Compositional matrix adjust.
 Identities = 116/159 (72%), Positives = 134/159 (84%)
 Frame = -3

Query: 1191 ELYARVYEELLAIPVVRGRKTEKEKFAGGDYTTTIEAFISASGRAIQGATSHHLGQNFSK 1250
            ELYARVYE+L+AIPVVRG KTEKEKFA GD+TTT+EA+ISA+GRAIQGATSHHLGQNFSK
Sbjct: 476  ELYARVYEDLMAIPVVRGHKTEKEKFAXGDFTTTVEAYISANGRAIQGATSHHLGQNFSK 297

Query: 1251 MCEIVFEDPKTPGEKQFAYQCSWGLTTRTIGVMVMVHGDNMGLVLPPRVASVQVVVIPCG 1310
            M EIV EDP+T  +KQ+ YQ SWG+TTRTIGVM MVHGDN+GLVLPPRVA VQVVV+PCG
Sbjct: 296  MFEIVIEDPETQ-QKQYVYQNSWGITTRTIGVMTMVHGDNVGLVLPPRVACVQVVVVPCG 120

Query: 1311 ITNALSEEDREALMAKCNEYRRRLLGANIRVRVDLRDNY 1349
            IT +LSE D ++L   C++    L G +IR R D RDNY
Sbjct: 119  ITASLSEADTKSLYDACDKJAADLKGQDIRARADCRDNY 3
>27596
          Length = 458

 Score =  206 bits (523), Expect = 8e-53,   Method: Compositional matrix adjust.
 Identities = 99/152 (65%), Positives = 120/152 (78%), Gaps = 1/152 (0%)
 Frame = +3

Query: 1212 EKEKFAGGDYTTTIEAFISASGRAIQGATSHHLGQNFSKMCEIVFEDPKTPGEKQFAYQC 1271
            EKEKFAG  YTTT+EA+I+A+GRAIQGATSHHLGQNFSKM E+VF+DP+T GEK++ YQ 
Sbjct: 3    EKEKFAGAAYTTTVEAYIAAAGRAIQGATSHHLGQNFSKMFEVVFDDPET-GEKRYVYQN 179

Query: 1272 SWGLTTRTIGVMVMVHGDNMGLVLPPRVASVQVVVIPCGITNALSEEDREALMAKCNEYR 1331
            SWG+TTRTIGV+ MVHGDN GLVLPP+VASVQVV++PCGIT  L ++DR+AL   C +  
Sbjct: 180  SWGITTRTIGVLTMVHGDNQGLVLPPKVASVQVVIVPCGITVNLKDDDRKALYESCKDLE 359

Query: 1332 RRLLGANIRVRVDL-RDNYSPGWKFNHWELKG 1362
            + L     + +  L R    PG KFNHWELKG
Sbjct: 360  KLLXRCRGQSQGRLPRKTTLPGGKFNHWELKG 455
>31189
          Length = 448

 Score = 77.4 bits (189), Expect(2) = 2e-22,   Method: Composition-based stats.
 Identities = 40/67 (59%), Positives = 45/67 (67%), Gaps = 3/67 (4%)
 Frame = -2

Query: 1449 GEIDCEDWIKKMTARDQDVEPGAPSMGAKSLCIPFNPLCELQPGAMCV---CGKNPAKFY 1505
            G   CED IKK +ARD  VE GAP+MGAK LCIPF    +L P   C+   C K PAK+Y
Sbjct: 306  GTFPCEDAIKKDSARDVVVEEGAPAMGAKGLCIPFTQPQQLPPATQCIHHACSK-PAKYY 130

Query: 1506 TLFGRSY 1512
            TLFGRSY
Sbjct: 129  TLFGRSY 109

 Score = 48.5 bits (114), Expect(2) = 2e-22,   Method: Composition-based stats.
 Identities = 22/44 (50%), Positives = 29/44 (65%)
 Frame = -1

Query: 1408 IQLNLFTRASEDLKTHMVVSNTLEDFQKVLDAGKVAQIPFCGEI 1451
            IQ NL+++A  DLK +M VS+   DF   LD  K+ Q PFCG+I
Sbjct: 430  IQSNLYSKAEADLKNNMAVSHDWNDFCSALDKQKLIQAPFCGDI 299
>28739
          Length = 461

 Score = 84.7 bits (208), Expect = 2e-16,   Method: Compositional matrix adjust.
 Identities = 46/124 (37%), Positives = 72/124 (58%), Gaps = 1/124 (0%)
 Frame = -2

Query: 3   ALCLTVNAGNPPLEALLAVEHVK-GDVSISVEEGKENLLRVSETVAFTDVNSILRYLARI 61
           A+C++++   P +   L  EH+K     +S   G++N L V +   F+   S+ RYLAR 
Sbjct: 427 AVCVSISKNKPAVAGALTAEHLKKSGNGVSWSFGQDNALAVDKDSVFSSSASVSRYLARA 248

Query: 62  ATTSGLYGTNLMEHTEIDHWLEFSATKLSSCDRLTSAINELNHCLSLRTYLVGNSLTLAD 121
             ++ L G  ++E TE+DHWL F+  +LS     T A++ L+  L   T+LVG++LTLAD
Sbjct: 247 FPSAKLQGETILEKTEVDHWLNFAYGQLSCASDFTVALDYLDSVLKPSTFLVGHALTLAD 68

Query: 122 LCVW 125
             VW
Sbjct: 67  FAVW 56
>05674
          Length = 1437

 Score = 80.1 bits (196), Expect = 7e-15,   Method: Compositional matrix adjust.
 Identities = 75/276 (27%), Positives = 118/276 (42%), Gaps = 11/276 (3%)
 Frame = -1

Query: 422  EYSRLNLNNTVLSKRKLTWFVNEGLVDGWDDPRFPTVRGVLRRGMTVEGLKQFIAAQGSS 481
            EY RLNL+  V+SKRK+   + EG V  WDDPR  T+  + RRG   E +  F A  G +
Sbjct: 1437 EYGRLNLHYAVVSKRKIGKLITEGFVRNWDDPRLFTLTALRRRGFPSEAINYFCAKVGVT 1258

Query: 482  RSVVNMEWDKIWAFNKKVIDPVAPRYVALLKKEVVPVNVLDAQEEMK-EVARHPKNPDVG 540
             +   ++   + A  ++V++  APR +A+L    V +    A    +  V   P +   G
Sbjct: 1257 MAKTVIDPVMLEACVREVLNVKAPRAMAVLDPLKVVIQNFPADHSGEVTVPNFPADESKG 1078

Query: 541  LKPVWYSPKVFIEGAD--------AETFSEGEMVTFINWG-NINITKIHKNADGKITSLD 591
               V  +  +FIE +D         +  +  + V   + G  I++  + K+ADG++  L 
Sbjct: 1077 SHKVPLTSIIFIERSDFREEADKNYKRLAVNQTVGLRHAGLVISVESVVKDADGQVAELV 898

Query: 592  AKLNLENKDYKKTTKITWLAESTHALSIPAVCVTYEHLITKPVLGKDEDFKQYINKDSKH 651
             K     +  K    I W+++  H   I      + H   +        F   +NKDS  
Sbjct: 897  VKCVNATETSKPKAFIHWVSQPLHC-EIRLYDTLFYHKNPEDPSEVPGGFLTDVNKDSLT 721

Query: 652  E-ELMLGDPCLKDLKKGDIIQLQRRGFFICDQPYEP 686
                 L D  +   K  D  Q +R GFF  D    P
Sbjct: 720  VLRTALVDNSVSGAKTYDKFQFERNGFFSVDPDSSP 613
>20405
          Length = 766

 Score = 44.7 bits (104), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 46/166 (27%), Positives = 74/166 (44%), Gaps = 25/166 (15%)
 Frame = -1

Query: 46  VAFTDVNSILRYLARIATTSGLYGTNLMEHTEIDHWLEFSATKL--SSC----------- 92
           V  T+ N+I  Y+A     + L G+++     I  W  ++ ++L  +SC           
Sbjct: 586 VLLTESNAIAYYVAN----ATLRGSDVATQAAIYQWASWADSELLPASCAWVFPYLGIMQ 419

Query: 93  ----------DRLTSAINELNHCLSLRTYLVGNSLTLADLCVWATLKGSAAWQEHLKQN- 141
                     + L +A+  L+  L  RT+LV   +TLAD+ V+ TL    A+Q  L  + 
Sbjct: 418 FNKQNVERAKNDLLAALKVLDGHLLTRTFLVTERITLADIIVFTTLIH--AFQNVLDASI 245

Query: 142 -KTLVHVKRWFGFLEAQQAFRSVGTKWDVSGNRATVAPDKKQDVGK 186
             +LV+V+RWF  L  Q    SV     +     T  P K QD+ +
Sbjct: 244 RSSLVNVQRWFLTLANQPQVASVVGNIVLCEAPPTYDPKKYQDLNQ 107
>20465
          Length = 842

 Score = 38.1 bits (87), Expect = 0.024,   Method: Composition-based stats.
 Identities = 25/86 (29%), Positives = 47/86 (54%), Gaps = 2/86 (2%)
 Frame = +2

Query: 53  SILRYLARIATTSGLYGTNLMEHTEIDHWLEFSATKL--SSCDRLTSAINELNHCLSLRT 110
           +I RYL+R+   +     +++  T ID  L+ +  +L   +    ++ +  LN  L   +
Sbjct: 47  NIARYLSRLLQPA-YDDVDIVTATHIDEVLDMAQQQLIQGNNKEKSAVLRTLNARLGKGS 223

Query: 111 YLVGNSLTLADLCVWATLKGSAAWQE 136
           +LVG +L+LAD+ VW+ L+G+    E
Sbjct: 224 WLVGANLSLADVVVWSALQGAKIASE 301
>10621
          Length = 1304

 Score = 38.1 bits (87), Expect = 0.024,   Method: Compositional matrix adjust.
 Identities = 25/71 (35%), Positives = 35/71 (49%)
 Frame = +2

Query: 94  RLTSAINELNHCLSLRTYLVGNSLTLADLCVWATLKGSAAWQEHLKQNKTLVHVKRWFGF 153
           ++T A+  LN  L  RTYLVG S+T AD+ +   L          +  K   +V RWF  
Sbjct: 404 QVTKALTVLNDYLLTRTYLVGESVTQADISLACNLIMLYEQVMDPEFRKPFQNVNRWFTT 583

Query: 154 LEAQQAFRSVG 164
           L  Q  F++V 
Sbjct: 584 LVNQPNFKAVA 616
>04150
          Length = 1425

 Score = 37.4 bits (85), Expect = 0.042,   Method: Compositional matrix adjust.
 Identities = 23/55 (41%), Positives = 28/55 (50%)
 Frame = -1

Query: 753 LYSRVAVQGDVVRELKAKKAPKEDIDAAVKQLLTLKAEYKEKTGQEYKPGNPSAA 807
           L   V  QG+ VRE+KA KA K  IDA V +LL LK +     G +     PS  
Sbjct: 639 LTEEVTAQGNKVREVKAAKADKATIDAQVAKLLDLKKQLALAQGVDPAAAAPSGG 475
>23211
          Length = 1156

 Score = 34.7 bits (78), Expect = 0.32,   Method: Compositional matrix adjust.
 Identities = 28/93 (30%), Positives = 41/93 (44%)
 Frame = +1

Query: 102 LNHCLSLRTYLVGNSLTLADLCVWATLKGSAAWQEHLKQNKTLVHVKRWFGFLEAQQAFR 161
           LN  L  RTYLVG S+T AD+ +   L          +  K   +V RWF  L  Q  F+
Sbjct: 10  LNDYLLTRTYLVGESVTQADISLACNLIMLYEQVMDPEFRKPFQNVNRWFXTLVNQPNFK 189

Query: 162 SVGTKWDVSGNRATVAPDKKQDVGKFVELPGAE 194
           +      V+G+        + D  K+ +L G +
Sbjct: 190 A------VAGDVTLAQKMAQFDAKKYGDLHGGQ 270
>20434
          Length = 990

 Score = 30.4 bits (67), Expect = 5.8,   Method: Composition-based stats.
 Identities = 16/54 (29%), Positives = 26/54 (48%), Gaps = 7/54 (12%)
 Frame = -3

Query: 1037 MIEYYDVSGCYILRPW-------SYSIWESIKDFFDAEIKKLGVENCYFPIFVS 1083
            +++ Y V  CYI  PW       S  IW  + D+    I K  +++C F + V+
Sbjct: 601  LLDMYTVGMCYIFFPWFCLCHCCSVLIWSGVVDWT*NNINKSILQSCLFWVNVN 440
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|21312044|ref|NP_082935.1| eukaryotic translation
initiation factor 3, subunit K [Mus musculus]
         (218 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

14290                                                                 152   3e-63
11214                                                                  63   8e-11
24108                                                                  53   9e-08
17767                                                                  29   1.5  
16468                                                                  28   2.1  
02969                                                                  28   3.7  
18645                                                                  27   9.3  
>14290
          Length = 871

 Score =  152 bits (383), Expect(2) = 3e-63,   Method: Compositional matrix adjust.
 Identities = 68/140 (48%), Positives = 95/140 (67%)
 Frame = +3

Query: 79  HTDFTLCKCMIDQAHQEERPIRQILYLGDLLETCHFQAFWQALDENMDLLEGITGFEDSV 138
           H DF LCKC+ID  H  E PI +IL L + LE C F+ FW  + ++ DL   + GFED+V
Sbjct: 303 HPDFMLCKCLIDSTHLTEIPISKILELAEDLEACDFEHFWMEVRDDPDLFSSVVGFEDNV 482

Query: 139 RKFICHVVGITYQHIDRWLLAEMLGDLTDNQLKVWMSKYGWSADESGQVFICSQEESIKP 198
           RK++CHV+  T+Q I+   L + LG +T    + W +KYGW+ D +G +F+ +QEESIK 
Sbjct: 483 RKYVCHVIAATFQTIEEEKLQQFLGHVTPMVAQQWANKYGWTTDSNGMIFVSNQEESIKT 662

Query: 199 KNIVEKIDFDSVSSIMASSQ 218
           KNI EKI FDSV+ IMA+++
Sbjct: 663 KNITEKITFDSVAGIMATTR 722

 Score =  107 bits (266), Expect(2) = 3e-63,   Method: Compositional matrix adjust.
 Identities = 56/86 (65%), Positives = 63/86 (73%), Gaps = 1/86 (1%)
 Frame = +1

Query: 3   MFEQMRANVGKLLKGIDRYNPE-NLATLERYVETQAKENAYDLEANLAVLKLYQFNPAFF 61
           M E MR  V  LL+GIDR     NL+TLERYV+ QA+EN YDLEA+LAVLKLYQFNP +F
Sbjct: 73  MAEAMRGTVASLLRGIDRLLTR*NLSTLERYVQMQAQENTYDLEASLAVLKLYQFNPGYF 252

Query: 62  QTTVTAQILLKALTNLPHTDFTLCKC 87
           QT + A ILLKALTNLP    TL  C
Sbjct: 253 QTEIAALILLKALTNLP----TLTSC 318
>11214
          Length = 1018

 Score = 63.2 bits (152), Expect = 8e-11,   Method: Compositional matrix adjust.
 Identities = 25/60 (41%), Positives = 39/60 (65%)
 Frame = -3

Query: 126 DLLEGITGFEDSVRKFICHVVGITYQHIDRWLLAEMLGDLTDNQLKVWMSKYGWSADESG 185
           +L   + GFED+VRK++CHV+  T+Q I+   L + LG +T    + W +KYGW+ D +G
Sbjct: 182 NLFSSVVGFEDNVRKYVCHVIAATFQTIEEEKLQQFLGHVTPMVAQQWANKYGWTTDSNG 3
>24108
          Length = 421

 Score = 53.1 bits (126), Expect = 9e-08,   Method: Compositional matrix adjust.
 Identities = 25/42 (59%), Positives = 33/42 (78%)
 Frame = +3

Query: 28  TLERYVETQAKENAYDLEANLAVLKLYQFNPAFFQTTVTAQI 69
           T++R   ++ +EN YDLEA+LAVLKLYQFNP +FQT + A I
Sbjct: 303 TMDR---SRVQENXYDLEASLAVLKLYQFNPGYFQTEIAALI 419
>17767
          Length = 489

 Score = 28.9 bits (63), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 15/50 (30%), Positives = 26/50 (52%), Gaps = 3/50 (6%)
 Frame = +2

Query: 97  RPIRQILYLGDLLETCHFQAFWQALDENMDLLEGITGF---EDSVRKFIC 143
           RPI  +  +G + E C ++  +  L +N  L E  +GF   + SV + +C
Sbjct: 83  RPISLLSCIGKVFEKCVYKYVYNYLIDNHILTESQSGFLPGDSSVNQLLC 232
>16468
          Length = 598

 Score = 28.5 bits (62), Expect = 2.1,   Method: Compositional matrix adjust.
 Identities = 14/39 (35%), Positives = 19/39 (48%), Gaps = 3/39 (7%)
 Frame = +3

Query: 51  LKLYQFNPAFFQTTVTAQILLKALTN---LPHTDFTLCK 86
           LKLY  NP  F  + TA  L     +   LP T  ++C+
Sbjct: 150 LKLYSLNPGLFTMSRTASSLFTEFISHW*LPETSASICR 266
>02969
          Length = 1689

 Score = 27.7 bits (60), Expect = 3.7,   Method: Compositional matrix adjust.
 Identities = 12/53 (22%), Positives = 27/53 (50%)
 Frame = -2

Query: 113 HFQAFWQALDENMDLLEGITGFEDSVRKFICHVVGITYQHIDRWLLAEMLGDL 165
            +Q + + L +   +++G+T  E SV++ +C V+   ++  D    A    D+
Sbjct: 767 RYQKYSRTLSQTPWIIDGVTKMEGSVQELVCQVILEKFRPTDHKFSASGREDV 609
>18645
          Length = 477

 Score = 26.6 bits (57), Expect = 9.3,   Method: Compositional matrix adjust.
 Identities = 12/39 (30%), Positives = 21/39 (53%)
 Frame = -2

Query: 57  NPAFFQTTVTAQILLKALTNLPHTDFTLCKCMIDQAHQE 95
           NP+ F   VT  +++K   +     F +C CMI +A ++
Sbjct: 224 NPSIFSLFVTRCLVVKRFQHCVLLKFLMCVCMI*KAFRD 108
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6754264|ref|NP_034616.1| ELAV-like 2 isoform 2 [Mus
musculus]
         (360 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

25691                                                                 207   3e-63
02343                                                                 113   1e-25
11687                                                                  92   5e-19
17775                                                                  89   2e-18
19868                                                                  69   3e-12
17681                                                                  67   2e-11
11019                                                                  65   5e-11
03744                                                                  65   5e-11
16427                                                                  64   1e-10
20488                                                                  62   3e-10
13457                                                                  61   8e-10
03000                                                                  61   9e-10
08958                                                                  60   1e-09
00556                                                                  60   1e-09
12350                                                                  59   3e-09
14258                                                                  59   4e-09
03406                                                                  58   7e-09
14637                                                                  58   7e-09
01278                                                                  56   2e-08
00302                                                                  51   6e-07
02140                                                                  50   2e-06
13822                                                                  49   2e-06
30672                                                                  49   3e-06
15371                                                                  49   3e-06
00029                                                                  49   4e-06
32733                                                                  48   5e-06
02415                                                                  48   7e-06
12506                                                                  47   1e-05
01937                                                                  47   1e-05
23322                                                                  45   4e-05
10194                                                                  45   6e-05
31310                                                                  44   8e-05
00738                                                                  44   8e-05
24983                                                                  44   9e-05
01065                                                                  44   1e-04
03059                                                                  42   3e-04
31618                                                                  42   3e-04
33516                                                                  42   3e-04
26197                                                                  41   7e-04
32386                                                                  41   7e-04
03200                                                                  40   0.001
31938                                                                  40   0.001
28652                                                                  40   0.001
23720                                                                  40   0.001
09968                                                                  40   0.001
04988                                                                  40   0.001
00817                                                                  40   0.002
19733                                                                  39   0.003
16016                                                                  39   0.004
24794                                                                  39   0.004
31265                                                                  38   0.006
15503                                                                  38   0.007
02347                                                                  37   0.009
25632                                                                  37   0.009
39789                                                                  36   0.022
05273                                                                  36   0.030
25746                                                                  35   0.034
29364                                                                  35   0.039
20169                                                                  35   0.053
02809                                                                  35   0.061
12096                                                                  35   0.065
03856                                                                  34   0.071
22492                                                                  34   0.090
23250                                                                  33   0.12 
28605                                                                  33   0.13 
11126                                                                  32   0.49 
33504                                                                  31   0.81 
19570                                                                  31   0.81 
28372                                                                  30   1.6  
35180                                                                  30   2.2  
>25691
          Length = 768

 Score =  207 bits (526), Expect(2) = 3e-63,   Method: Compositional matrix adjust.
 Identities = 100/141 (70%), Positives = 117/141 (82%)
 Frame = -2

Query: 67  SCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYARPSSASIRDAN 126
           +CKL+RDK TGQSLGYGFVNY   +DA+KAI+TLNGLRLQ KTIKVS ARPS  SI+ AN
Sbjct: 434 TCKLIRDKPTGQSLGYGFVNYKRQEDADKAIHTLNGLRLQNKTIKVSLARPSCESIKGAN 255

Query: 127 LYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGISRGVGFIRFDKRIEAEEAIKGL 186
           LY+SGLPK++TQ +LE LF+  G IITSRIL DQ TG+S+GVGFIRFD+RIEAE AI+ L
Sbjct: 254 LYISGLPKSLTQLDLENLFTDCGNIITSRILYDQTTGLSKGVGFIRFDQRIEAERAIQKL 75

Query: 187 NGQKPPGATEPITVKFANNPS 207
           N   P G  +PITVKFAN+PS
Sbjct: 74  NNHIPDGCIDPITVKFANSPS 12

 Score = 53.1 bits (126), Expect(2) = 3e-63,   Method: Compositional matrix adjust.
 Identities = 23/30 (76%), Positives = 28/30 (93%)
 Frame = -1

Query: 37  SKTNLIVNYLPQNMTQEELKSLFGSIGEIE 66
           SKTNLIVNYLPQ M+Q+E++SLF SIGE+E
Sbjct: 525 SKTNLIVNYLPQTMSQDEIRSLFASIGELE 436

 Score = 40.0 bits (92), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 19/47 (40%), Positives = 29/47 (61%)
 Frame = -2

Query: 306 VKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQVSF 352
            K+IRD  T +  G+GFV     ++A  AI +LNG RL ++ ++VS 
Sbjct: 431 CKLIRDKPTGQSLGYGFVNYKRQEDADKAIHTLNGLRLQNKTIKVSL 291
>02343
          Length = 1715

 Score =  113 bits (283), Expect = 1e-25,   Method: Compositional matrix adjust.
 Identities = 66/176 (37%), Positives = 98/176 (55%)
 Frame = -2

Query: 37   SKTNLIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKA 96
            SKTNL +  L  N T ++L +L    G I S K + D+ T +  GYGFV++  P  AE+A
Sbjct: 1270 SKTNLYIRGLSPNTTDKDLVNLCQHFGTITSTKAIIDQTTNKCKGYGFVDFDAPGAAERA 1091

Query: 97   INTLNGLRLQTKTIKVSYARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRI 156
            +  L    +Q +  K     P+       NLY++ LP   T+K LE LF  YG +I++RI
Sbjct: 1090 VQALQAQGIQAQMAKQQEQDPT-------NLYIANLPLHFTEKHLEGLFKDYGTVISTRI 932

Query: 157  LVDQVTGISRGVGFIRFDKRIEAEEAIKGLNGQKPPGATEPITVKFANNPSQKTNQ 212
            L  +  GISR VGF R + R + +  I   N +   G +EP+ VKFA++ ++K +Q
Sbjct: 931  L-RKPDGISRCVGFARMESRDKCDTVINTFNNKMISGCSEPLLVKFADSGNKKKSQ 767

 Score = 54.3 bits (129), Expect = 7e-08,   Method: Compositional matrix adjust.
 Identities = 24/68 (35%), Positives = 37/68 (54%)
 Frame = -2

Query: 122  IRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGISRGVGFIRFDKRIEAEE 181
            +   NLY+ GL    T K+L  L   +G I +++ ++DQ T   +G GF+ FD    AE 
Sbjct: 1273 LSKTNLYIRGLSPNTTDKDLVNLCQHFGTITSTKAIIDQTTNKCKGYGFVDFDAPGAAER 1094

Query: 182  AIKGLNGQ 189
            A++ L  Q
Sbjct: 1093 AVQALQAQ 1070

 Score = 44.7 bits (104), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 23/70 (32%), Positives = 36/70 (51%)
 Frame = -2

Query: 271  GHPGTGWCIFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDE 330
            G P +   +++  L+P+  +  L  +   FG +T+ K I D  TNKCKG+GFV       
Sbjct: 1282 GDPLSKTNLYIRGLSPNTTDKDLVNLCQHFGTITSTKAIIDQTTNKCKGYGFVDFDAPGA 1103

Query: 331  AAMAIASLNG 340
            A  A+ +L  
Sbjct: 1102 AERAVQALQA 1073
>11687
          Length = 676

 Score = 91.7 bits (226), Expect = 5e-19,   Method: Compositional matrix adjust.
 Identities = 60/194 (30%), Positives = 99/194 (51%), Gaps = 9/194 (4%)
 Frame = +3

Query: 20  TVNNNCSSPVDSGNTEDSKT-NLIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQ 78
           T N N S+ V S    D+ +  + V  +P+NM + EL+ +F   G + S  ++RDK TGQ
Sbjct: 90  TSNMNPSTQVTSQGEPDADSIKMFVGQIPRNMDENELRKMFEDYGPVHSLNILRDKNTGQ 269

Query: 79  SLGYGFVNYIDPK---DAEKAINTLNGLRLQTKTIKV----SYARPSSASIRDANLYVSG 131
           S G  FV +   K   DA+ A++ +  + +    +++    S  R    ++ +  L+V  
Sbjct: 270 SKGCCFVTFFTRKAALDAQNALHNVKTMPMMHHPVQMKPADSEKRNGERNVEERKLFVGM 449

Query: 132 LPKTMTQKELEQLFSQYGRIITSRILVDQVTGISRGVGFIRFDKRIEAEEAIKGL-NGQK 190
           L K +++ ++  LF  +G I    +L D   G SRG  FI F  R  A  +IKG+ + Q 
Sbjct: 450 LSKKLSENDVRMLFESFGSIDDCTVLRDS-NGTSRGCAFITFASRQCAMNSIKGMHHSQT 626

Query: 191 PPGATEPITVKFAN 204
             G + P+ VK A+
Sbjct: 627 MEGCSSPLVVKMAD 668

 Score = 38.1 bits (87), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 21/64 (32%), Positives = 35/64 (54%)
 Frame = +3

Query: 279 IFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 338
           +FV  +  + DE+ L +MF  +G V ++ ++RD NT + KG  FVT      A  A  +L
Sbjct: 156 MFVGQIPRNMDENELRKMFEDYGPVHSLNILRDKNTGQSKGCCFVTFFTRKAALDAQNAL 335

Query: 339 NGYR 342
           +  +
Sbjct: 336 HNVK 347

 Score = 29.6 bits (65), Expect = 2.1,   Method: Compositional matrix adjust.
 Identities = 16/61 (26%), Positives = 31/61 (50%)
 Frame = +3

Query: 279 IFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 338
           +FV  L+    E+ +  +F  FG++ +  V+RD N    +G  F+T  +   A  +I  +
Sbjct: 435 LFVGMLSKKLSENDVRMLFESFGSIDDCTVLRDSNGTS-RGCAFITFASRQCAMNSIKGM 611

Query: 339 N 339
           +
Sbjct: 612 H 614
>17775
          Length = 1282

 Score = 89.4 bits (220), Expect = 2e-18,   Method: Compositional matrix adjust.
 Identities = 50/152 (32%), Positives = 87/152 (57%), Gaps = 2/152 (1%)
 Frame = -2

Query: 39   TNLIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAIN 98
             +L V  L  ++T+  L   F + G + S ++ RD IT +SLGY +VN+  P DAE+A++
Sbjct: 1194 ASLYVGDLHPDVTEAMLFEKFSTAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALD 1015

Query: 99   TLNGLRLQTKTIKVSYAR--PSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRI 156
            T+N   ++ + I++ +++  PS       N+++  L KT+  K L   FS +G I++ +I
Sbjct: 1014 TMNFDTVKGRPIRIMWSQRDPSVRKSGVGNVFIKNLDKTIDNKALYDTFSAFGNILSCKI 835

Query: 157  LVDQVTGISRGVGFIRFDKRIEAEEAIKGLNG 188
              D+    S+G GF+ F+    A +AI  +NG
Sbjct: 834  ACDEQG--SKGYGFVHFETEEAARQAIDKVNG 745

 Score = 74.7 bits (182), Expect = 5e-14,   Method: Compositional matrix adjust.
 Identities = 79/328 (24%), Positives = 134/328 (40%), Gaps = 8/328 (2%)
 Frame = -2

Query: 40  NLIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINT 99
           N+ +  L + +  + L   F + G I SCK+  D+    S GYGFV++   + A +AI+ 
Sbjct: 927 NVFIKNLDKTIDNKALYDTFSAFGNILSCKIACDEQG--SKGYGFVHFETEEAARQAIDK 754

Query: 100 LNGLRLQTKTIKVSYARPSSASI--------RDANLYVSGLPKTMTQKELEQLFSQYGRI 151
           +NG+ L  K + V    P    I        R  N+YV         +    L  Q  + 
Sbjct: 753 VNGMLLNGKKVYVGRFIPRKERIMMMGDKLKRFNNVYVKNFC*GTG*RPAA*LVWQARQD 574

Query: 152 ITSRILVDQVTGISRGVGFIRFDKRIEAEEAIKGLNGQKPPGATEPITVKFANNPSQKTN 211
                      G SRG GF+ F++   AE+A+  +NG +  G                  
Sbjct: 573 HLXXGACRGEDGKSRGFGFVSFEEPEGAEKAVDEINGTEVSGR----------------- 445

Query: 212 QAILSQLYQSPNRRYPGPLAQQAQRFRLDNLLNMAYGVKSRFSPMTIDGMTSLAGINIPG 271
             I+          Y G   ++A+R            +K RF  + ++ +    G+N+  
Sbjct: 444 --II----------YCGRAQKRAER---------QAELKERFEKIKLERINRYQGVNL-- 334

Query: 272 HPGTGWCIFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEA 331
                   +V NL    D+  L + F  FG +T+ K++ +    + KGFGFV  ++ +EA
Sbjct: 333 --------YVKNLDDSIDDERLRKEFSNFGTITSAKIMTE--GGRSKGFGFVCFSSPEEA 184

Query: 332 AMAIASLNGYRLGDRVLQVSFKTNKTHK 359
             A+  +NG  +  + L V+    K  +
Sbjct: 183 TKAVTEMNGRIIVAKPLYVALAQRKEDR 100

 Score = 62.0 bits (149), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 42/154 (27%), Positives = 77/154 (50%), Gaps = 18/154 (11%)
 Frame = -2

Query: 77  GQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYARPSS---ASIRD--------- 124
           G+S G+GFV++ +P+ AEKA++ +NG  +  + I    A+  +   A +++         
Sbjct: 540 GKSRGFGFVSFEEPEGAEKAVDEINGTEVSGRIIYCGRAQKRAERQAELKERFEKIKLER 361

Query: 125 ------ANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGISRGVGFIRFDKRIE 178
                  NLYV  L  ++  + L + FS +G I +++I+ +   G S+G GF+ F    E
Sbjct: 360 INRYQGVNLYVKNLDDSIDDERLRKEFSNFGTITSAKIMTE--GGRSKGFGFVCFSSPEE 187

Query: 179 AEEAIKGLNGQKPPGATEPITVKFANNPSQKTNQ 212
           A +A+  +NG+      +P+ V  A     +  Q
Sbjct: 186 ATKAVTEMNGRII--VAKPLYVALAQRKEDRRAQ 91
>19868
          Length = 434

 Score = 68.9 bits (167), Expect = 3e-12,   Method: Compositional matrix adjust.
 Identities = 40/141 (28%), Positives = 68/141 (48%), Gaps = 4/141 (2%)
 Frame = +2

Query: 40  NLIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEK---- 95
            + V  L    + E L+  F   GEI    +++D  T +S G+GF+ + DP   +K    
Sbjct: 2   KMFVGGLSWQTSPESLRDYFNKFGEITEVMVMKDPTTRRSRGFGFITFGDPASVDKVLAQ 181

Query: 96  AINTLNGLRLQTKTIKVSYARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSR 155
           A + L+G ++  K      A P   + R   ++V GL    T ++++  F Q+G I  + 
Sbjct: 182 ATHELDGKKIDPKVAFPRRAHPRMVT-RTKKIFVGGLSAPTTLEDVKNYFEQFGPIEDAM 358

Query: 156 ILVDQVTGISRGVGFIRFDKR 176
           ++ D+ T   RG GF+   KR
Sbjct: 359 LMFDKQTNRHRGFGFVTISKR 421

 Score = 37.4 bits (85), Expect = 0.010,   Method: Compositional matrix adjust.
 Identities = 23/73 (31%), Positives = 37/73 (50%), Gaps = 4/73 (5%)
 Frame = +2

Query: 279 IFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTM---TNYDEA-AMA 334
           +FV  L+       L   F  FG +T V V++D  T + +GFGF+T     + D+  A A
Sbjct: 5   MFVGGLSWQTSPESLRDYFNKFGEITEVMVMKDPTTRRSRGFGFITFGDPASVDKVLAQA 184

Query: 335 IASLNGYRLGDRV 347
              L+G ++  +V
Sbjct: 185 THELDGKKIDPKV 223

 Score = 30.8 bits (68), Expect = 0.82,   Method: Compositional matrix adjust.
 Identities = 16/49 (32%), Positives = 26/49 (53%)
 Frame = +2

Query: 279 IFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTN 327
           IFV  L+       +   F  FG + +  ++ D  TN+ +GFGFVT++ 
Sbjct: 272 IFVGGLSAPTTLEDVKNYFEQFGPIEDAMLMFDKQTNRHRGFGFVTISK 418
>17681
          Length = 964

 Score = 66.6 bits (161), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 29/78 (37%), Positives = 48/78 (61%)
 Frame = +2

Query: 279 IFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 338
           IFV +L+P+ +   L + F PFG ++N +++RD  T K KG+ FV+     EA  AI ++
Sbjct: 38  IFVGDLSPEIETETLREAFAPFGEISNCRIVRDPQTMKSKGYAFVSFVKKAEAENAIQAM 217

Query: 339 NGYRLGDRVLQVSFKTNK 356
           NG  +G R ++ ++ T K
Sbjct: 218 NGQWIGSRSIRTNWSTRK 271

 Score = 64.3 bits (155), Expect = 8e-11,   Method: Compositional matrix adjust.
 Identities = 48/193 (24%), Positives = 79/193 (40%), Gaps = 45/193 (23%)
 Frame = +2

Query: 37  SKTNLIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKA 96
           S  ++ V  L   +  E L+  F   GEI +C++VRD  T +S GY FV+++   +AE A
Sbjct: 26  SHHHIFVGDLSPEIETETLREAFAPFGEISNCRIVRDPQTMKSKGYAFVSFVKKAEAENA 205

Query: 97  INTLNGLRLQTKTIKVSYA-------RPSSASIR-------------------------- 123
           I  +NG  + +++I+ +++       R SS S                            
Sbjct: 206 IQAMNGQWIGSRSIRTNWSTRKLPPPRESSKSGGQGGGMGGMGGCGGGAGNGIKNNQRHT 385

Query: 124 -----------DANLYVSGLPKTMTQKEL-EQLFSQYGRIITSRILVDQVTGISRGVGFI 171
                      +  +Y  G P  +   EL  + F Q+G I   R+  D      +G  FI
Sbjct: 386 FEEVYNQSSPTNTTVYCGGFPPNVISDELMHKHFMQFGPIQDVRVFKD------KGFAFI 547

Query: 172 RFDKRIEAEEAIK 184
           +F  +  A  AI+
Sbjct: 548 KFVTKEAAARAIE 586

 Score = 50.4 bits (119), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 47/211 (22%), Positives = 86/211 (40%), Gaps = 1/211 (0%)
 Frame = +2

Query: 126 NLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGISRGVGFIRFDKRIEAEEAIKG 185
           +++V  L   +  + L + F+ +G I   RI+ D  T  S+G  F+ F K+ EAE AI+ 
Sbjct: 35  HIFVGDLSPEIETETLREAFAPFGEISNCRIVRDPQTMKSKGYAFVSFVKKAEAENAIQA 214

Query: 186 LNGQKPPGATEPITVKFANNPSQKTNQAILSQLYQSPNRRYPGPLAQQAQRFRLDNLLNM 245
           +NGQ            +  + S +TN +          R+ P P        +   +  M
Sbjct: 215 MNGQ------------WIGSRSIRTNWS---------TRKLPPPRESSKSGGQGGGMGGM 331

Query: 246 AYGVKSRFSPMTIDGMTSLAGINIPGHPGTGWCIFVYNLAPDA-DESILWQMFGPFGAVT 304
                   + +  +   +   +     P T   ++     P+   + ++ + F  FG + 
Sbjct: 332 GGCGGGAGNGIKNNQRHTFEEVYNQSSP-TNTTVYCGGFPPNVISDELMHKHFMQFGPIQ 508

Query: 305 NVKVIRDFNTNKCKGFGFVTMTNYDEAAMAI 335
           +V+V +D      KGF F+     + AA AI
Sbjct: 509 DVRVFKD------KGFAFIKFVTKEAAARAI 583
>11019
          Length = 552

 Score = 65.1 bits (157), Expect = 5e-11,   Method: Compositional matrix adjust.
 Identities = 42/153 (27%), Positives = 71/153 (46%), Gaps = 24/153 (15%)
 Frame = -1

Query: 46  LPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAI-------- 97
           L    T E L+S F   GEI+   +++D  + +S G+GFV Y DP + +  +        
Sbjct: 543 LSWQTTTETLRSYFEKFGEIKESMVMKDPTSKRSRGFGFVTYKDPSNVDNVLANGPHCID 364

Query: 98  -NTLNGLRLQT-------------KTIKVSYARPSSASI--RDANLYVSGLPKTMTQKEL 141
             TLN   + T                KV++ R S+  +  +   ++V GL  + T +++
Sbjct: 363 SKTLNFSNMTTFYSNQDLLPYPPQVDPKVAFPRKSNPRMVTKTKKIFVGGLSSSTTVEDI 184

Query: 142 EQLFSQYGRIITSRILVDQVTGISRGVGFIRFD 174
           +  F  YG I  + ++ D+VT   RG  F+ FD
Sbjct: 183 KNYFKAYGTIEEATLMFDKVTSRHRGFAFVTFD 85

 Score = 35.0 bits (79), Expect = 0.051,   Method: Compositional matrix adjust.
 Identities = 43/221 (19%), Positives = 80/221 (36%)
 Frame = -1

Query: 129 VSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGISRGVGFIRFDKRIEAEEAIKGLNG 188
           + GL    T + L   F ++G I  S ++ D  +  SRG GF+ +      +  +   NG
Sbjct: 552 IGGLSWQTTTETLRSYFEKFGEIKESMVMKDPTSKRSRGFGFVTYKDPSNVDNVL--ANG 379

Query: 189 QKPPGATEPITVKFANNPSQKTNQAILSQLYQSPNRRYPGPLAQQAQRFRLDNLLNMAYG 248
              P   +  T+ F+N  +  +NQ +L          YP P       F   +   M   
Sbjct: 378 ---PHCIDSKTLNFSNMTTFYSNQDLLP---------YP-PQVDPKVAFPRKSNPRMVTK 238

Query: 249 VKSRFSPMTIDGMTSLAGINIPGHPGTGWCIFVYNLAPDADESILWQMFGPFGAVTNVKV 308
            K                            IFV  L+       +   F  +G +    +
Sbjct: 237 TKK---------------------------IFVGGLSSSTTVEDIKNYFKAYGTIEEATL 139

Query: 309 IRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQ 349
           + D  T++ +GF FVT  N +     +  ++ + +  ++++
Sbjct: 138 MFDKVTSRHRGFAFVTFDN-ESTVDKVCEIHFHEINSKMVE 19
>03744
          Length = 3486

 Score = 64.7 bits (156), Expect = 5e-11,   Method: Compositional matrix adjust.
 Identities = 37/94 (39%), Positives = 53/94 (56%)
 Frame = -1

Query: 266  GINIPGHPGTGWCIFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTM 325
            G  +PG  G    +F+Y+L  +  +  L QMF PFG V + KV  D  TN  K FGFV+ 
Sbjct: 3243 GPRVPGPDGAN--LFIYHLPQEFGDQDLMQMFMPFGNVVSAKVFIDKQTNLSKCFGFVSY 3070

Query: 326  TNYDEAAMAIASLNGYRLGDRVLQVSFKTNKTHK 359
             +   A  AI S+NG+++G + L+V  K +K  K
Sbjct: 3069 DSPLAAQAAITSMNGFQIGMKRLKVQLKRSKNDK 2968

 Score = 58.2 bits (139), Expect = 5e-09,   Method: Compositional matrix adjust.
 Identities = 28/78 (35%), Positives = 43/78 (55%)
 Frame = -1

Query: 39   TNLIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAIN 98
             NL + +LPQ    ++L  +F   G + S K+  DK T  S  +GFV+Y  P  A+ AI 
Sbjct: 3216 ANLFIYHLPQEFGDQDLMQMFMPFGNVVSAKVFIDKQTNLSKCFGFVSYDSPLAAQAAIT 3037

Query: 99   TLNGLRLQTKTIKVSYAR 116
            ++NG ++  K +KV   R
Sbjct: 3036 SMNGFQIGMKRLKVQLKR 2983

 Score = 57.4 bits (137), Expect = 8e-09,   Method: Compositional matrix adjust.
 Identities = 20/64 (31%), Positives = 42/64 (65%)
 Frame = -1

Query: 125  ANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGISRGVGFIRFDKRIEAEEAIK 184
            ANL++  LP+    ++L Q+F  +G ++++++ +D+ T +S+  GF+ +D  + A+ AI 
Sbjct: 3216 ANLFIYHLPQEFGDQDLMQMFMPFGNVVSAKVFIDKQTNLSKCFGFVSYDSPLAAQAAIT 3037

Query: 185  GLNG 188
             +NG
Sbjct: 3036 SMNG 3025
>16427
          Length = 1313

 Score = 63.9 bits (154), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 27/68 (39%), Positives = 48/68 (70%)
 Frame = +1

Query: 123 RDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGISRGVGFIRFDKRIEAEEA 182
           R   L+V GL + + +K LE+ FS++GRI  S ++ D+V  +SRG GF+ ++  ++AEEA
Sbjct: 130 RPGKLFVGGLAEEIDEKVLEREFSKFGRITESMVIRDKVRQVSRGFGFVTYENPMDAEEA 309

Query: 183 IKGLNGQK 190
           +K ++G++
Sbjct: 310 VKHMDGKE 333

 Score = 53.5 bits (127), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 26/81 (32%), Positives = 43/81 (53%)
 Frame = +1

Query: 35  EDSKTNLIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAE 94
           +D    L V  L + + ++ L+  F   G I    ++RDK+   S G+GFV Y +P DAE
Sbjct: 124 KDRPGKLFVGGLAEEIDEKVLEREFSKFGRITESMVIRDKVRQVSRGFGFVTYENPMDAE 303

Query: 95  KAINTLNGLRLQTKTIKVSYA 115
           +A+  ++G  +  K + V  A
Sbjct: 304 EAVKHMDGKEILGKKLHVEDA 366

 Score = 52.0 bits (123), Expect = 4e-07,   Method: Compositional matrix adjust.
 Identities = 27/72 (37%), Positives = 39/72 (54%)
 Frame = +1

Query: 279 IFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 338
           +FV  LA + DE +L + F  FG +T   VIRD      +GFGFVT  N  +A  A+  +
Sbjct: 142 LFVGGLAEEIDEKVLEREFSKFGRITESMVIRDKVRQVSRGFGFVTYENPMDAEEAVKHM 321

Query: 339 NGYRLGDRVLQV 350
           +G  +  + L V
Sbjct: 322 DGKEILGKKLHV 357
>20488
          Length = 3281

 Score = 62.4 bits (150), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 43/121 (35%), Positives = 63/121 (52%)
 Frame = +2

Query: 239  LDNLLNMAYGVKSRFSPMTIDGMTSLAGINIPGHPGTGWCIFVYNLAPDADESILWQMFG 298
            L  L+N A    + F+P       + AG +  G  G    +F+Y+L  +  +  L QMF 
Sbjct: 2603 LSGLVNQA-SFPNAFNPQAQMQQANSAGKHSEGPDGAN--LFIYHLPQEFGDQDLMQMFM 2773

Query: 299  PFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQVSFKTNKTH 358
            PFG V + KV  D  TN  K FGFV+  +   A  AI S+NG+++G + L+V  K +K  
Sbjct: 2774 PFGNVVSAKVFIDKQTNLSKCFGFVSYDSPLAAQAAITSMNGFQIGMKRLKVQLKRSKND 2953

Query: 359  K 359
            K
Sbjct: 2954 K 2956

 Score = 58.5 bits (140), Expect = 4e-09,   Method: Compositional matrix adjust.
 Identities = 24/88 (27%), Positives = 49/88 (55%)
 Frame = +2

Query: 101  NGLRLQTKTIKVSYARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQ 160
            N    Q +  + + A   S     ANL++  LP+    ++L Q+F  +G ++++++ +D+
Sbjct: 2636 NAFNPQAQMQQANSAGKHSEGPDGANLFIYHLPQEFGDQDLMQMFMPFGNVVSAKVFIDK 2815

Query: 161  VTGISRGVGFIRFDKRIEAEEAIKGLNG 188
             T +S+  GF+ +D  + A+ AI  +NG
Sbjct: 2816 QTNLSKCFGFVSYDSPLAAQAAITSMNG 2899

 Score = 57.8 bits (138), Expect = 7e-09,   Method: Compositional matrix adjust.
 Identities = 28/78 (35%), Positives = 43/78 (55%)
 Frame = +2

Query: 39   TNLIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAIN 98
             NL + +LPQ    ++L  +F   G + S K+  DK T  S  +GFV+Y  P  A+ AI 
Sbjct: 2708 ANLFIYHLPQEFGDQDLMQMFMPFGNVVSAKVFIDKQTNLSKCFGFVSYDSPLAAQAAIT 2887

Query: 99   TLNGLRLQTKTIKVSYAR 116
            ++NG ++  K +KV   R
Sbjct: 2888 SMNGFQIGMKRLKVQLKR 2941
>13457
          Length = 4857

 Score = 60.8 bits (146), Expect = 8e-10,   Method: Compositional matrix adjust.
 Identities = 34/88 (38%), Positives = 50/88 (56%), Gaps = 1/88 (1%)
 Frame = -1

Query: 123  RDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGISRGVGFIRFDKRIEAEEA 182
             D  L+V  L K  T++++ QLF  YG I    IL DQ  G S+G  F+++    EA+ A
Sbjct: 3414 EDRKLFVGMLNKQQTEEDVRQLFHPYGAIEECTILRDQ-NGNSKGCAFVKYSTHSEAQAA 3238

Query: 183  IKGLNG-QKPPGATEPITVKFANNPSQK 209
            I  L+G Q  PGA+  + VKFA+   ++
Sbjct: 3237 INALHGSQTMPGASSSLVVKFADTEKER 3154

 Score = 38.9 bits (89), Expect(2) = 4e-07,   Method: Compositional matrix adjust.
 Identities = 19/46 (41%), Positives = 26/46 (56%)
 Frame = -3

Query: 276  GWCIFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFG 321
            G  +F+Y+L     ++ L QMF PFG V + KV  D  TN+ K  G
Sbjct: 2425 GCNLFIYHLPQXXGDAELAQMFVPFGNVISAKVYVDRATNQSKCLG 2288

 Score = 32.3 bits (72), Expect(2) = 4e-07,   Method: Compositional matrix adjust.
 Identities = 15/37 (40%), Positives = 23/37 (62%)
 Frame = -2

Query: 320  FGFVTMTNYDEAAMAIASLNGYRLGDRVLQVSFKTNK 356
            FGFV+  N   A  AI ++NG+++G + L+V  K  K
Sbjct: 2294 FGFVSFDNPASAQAAIQAMNGFQIGMKRLKVQLKRPK 2184

 Score = 37.7 bits (86), Expect(2) = 8e-05,   Method: Compositional matrix adjust.
 Identities = 15/44 (34%), Positives = 28/44 (63%)
 Frame = -3

Query: 126  NLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGISRGVG 169
            NL++  LP+     EL Q+F  +G +I++++ VD+ T  S+ +G
Sbjct: 2419 NLFIYHLPQXXGDAELAQMFVPFGNVISAKVYVDRATNQSKCLG 2288

 Score = 25.4 bits (54), Expect(2) = 8e-05,   Method: Compositional matrix adjust.
 Identities = 14/50 (28%), Positives = 22/50 (44%), Gaps = 12/50 (24%)
 Frame = -2

Query: 169  GFIRFDKRIEAEEAIKGLNG------------QKPPGATEPITVKFANNP 206
            GF+ FD    A+ AI+ +NG            ++P  A  P  V + + P
Sbjct: 2291 GFVSFDNPASAQAAIQAMNGFQIGMKRLKVQLKRPKDANRPY*VHWVDPP 2142

 Score = 44.3 bits (103), Expect = 9e-05,   Method: Compositional matrix adjust.
 Identities = 25/77 (32%), Positives = 36/77 (46%), Gaps = 13/77 (16%)
 Frame = -1

Query: 277  WC-------------IFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFV 323
            WC             +FV  L     E  + Q+F P+GA+    ++RD N N  KG  FV
Sbjct: 3447 WCRLTPKMTIGEDRKLFVGMLNKQQTEEDVRQLFHPYGAIEECTILRDQNGNS-KGCAFV 3271

Query: 324  TMTNYDEAAMAIASLNG 340
              + + EA  AI +L+G
Sbjct: 3270 KYSTHSEAQAAINALHG 3220

 Score = 38.1 bits (87), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 15/40 (37%), Positives = 25/40 (62%)
 Frame = -2

Query: 82   YGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYARPSSAS 121
            +GFV++ +P  A+ AI  +NG ++  K +KV   RP  A+
Sbjct: 2294 FGFVSFDNPASAQAAIQAMNGFQIGMKRLKVQLKRPKDAN 2175
>03000
          Length = 778

 Score = 60.8 bits (146), Expect = 9e-10,   Method: Compositional matrix adjust.
 Identities = 42/164 (25%), Positives = 79/164 (48%), Gaps = 14/164 (8%)
 Frame = +3

Query: 41  LIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAI--- 97
           L +  L     ++ L+S F + GEI  C ++RD  + +S G+GF+ Y D +  ++A    
Sbjct: 93  LFIGGLSYETDEDSLRSHFETWGEIVDCIVMRDSNSKRSRGFGFITYKDAESIDQAQANR 272

Query: 98  -NTLNGLRLQTKTIKVSYARPSSASIRDA------NLYVSGLPKTMTQKELEQLFSQYGR 150
            + ++G  + TK      A P   S R         ++V G+ +  T+  +   F+++G 
Sbjct: 273 PHKIDGREVDTKR-----AMPREESGRSEVQQSVKKMFVGGVKEDTTEDMIRDTFNEFGE 437

Query: 151 IITSRILVDQVTGISRGVGFIRFDKRIEAEEAI----KGLNGQK 190
           I    ++ D+ TG +RG  F+ F      ++A+      LNG++
Sbjct: 438 ITGVDLIQDKGTGKNRGFCFVTFGDHDSVDKAVLKKRHDLNGRQ 569

 Score = 44.3 bits (103), Expect = 8e-05,   Method: Compositional matrix adjust.
 Identities = 23/69 (33%), Positives = 36/69 (52%), Gaps = 4/69 (5%)
 Frame = +3

Query: 279 IFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAI--- 335
           +FV  +  D  E ++   F  FG +T V +I+D  T K +GF FVT  ++D    A+   
Sbjct: 366 MFVGGVKEDTTEDMIRDTFNEFGEITGVDLIQDKGTGKNRGFCFVTFGDHDSVDKAVLKK 545

Query: 336 -ASLNGYRL 343
              LNG ++
Sbjct: 546 RHDLNGRQV 572

 Score = 40.4 bits (93), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 18/58 (31%), Positives = 32/58 (55%)
 Frame = +3

Query: 279 IFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIA 336
           +F+  L+ + DE  L   F  +G + +  V+RD N+ + +GFGF+T  + +    A A
Sbjct: 93  LFIGGLSYETDEDSLRSHFETWGEIVDCIVMRDSNSKRSRGFGFITYKDAESIDQAQA 266
>08958
          Length = 680

 Score = 60.5 bits (145), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 46/171 (26%), Positives = 84/171 (49%), Gaps = 7/171 (4%)
 Frame = +2

Query: 38  KTNLIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAI 97
           +  L V  L  ++++++ K LF   GE+               G+GF+      +AE A 
Sbjct: 65  RCRLFVGNLTPDVSEDDFKKLFSPFGEVSEA------YVNSGRGFGFIRLDYRHNAEAAK 226

Query: 98  NTLNGLRLQTKTIKVSYARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRIL 157
             L+GL+ + ++++V YA   +A      L V  L   ++ + LEQ F+Q+G +  + ++
Sbjct: 227 AALDGLQRKGRSLRVRYATHGAA------LKVKNLHPYVSNELLEQAFTQFGDLERAIVI 388

Query: 158 VDQVTGISRGVGFIRFDKRIEAEEAIKGLN------GQKP-PGATEPITVK 201
           VD+  G S G G + F ++  A++A++ +N      G  P P   EP+  K
Sbjct: 389 VDE-RGRSTGEGVVEFVRKPGAQQALRRINEGVFLFGADPKPIEVEPLEHK 538

 Score = 53.5 bits (127), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 30/82 (36%), Positives = 43/82 (52%), Gaps = 1/82 (1%)
 Frame = +2

Query: 275 TGWC-IFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAM 333
           TG C +FV NL PD  E    ++F PFG V+   V      N  +GFGF+ +     A  
Sbjct: 59  TGRCRLFVGNLTPDVSEDDFKKLFSPFGEVSEAYV------NSGRGFGFIRLDYRHNAEA 220

Query: 334 AIASLNGYRLGDRVLQVSFKTN 355
           A A+L+G +   R L+V + T+
Sbjct: 221 AKAALDGLQRKGRSLRVRYATH 286
>00556
          Length = 2189

 Score = 60.5 bits (145), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 31/87 (35%), Positives = 49/87 (56%)
 Frame = +3

Query: 29  VDSGNTEDSKTNLIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYI 88
           V S   +DS   + +  LP  ++++++K L  S G ++S  LVRD  TG S G+ F  Y+
Sbjct: 729 VVSTVVQDSDHKIFMGGLPSYLSEDQMKELLLSFGPLKSFNLVRDNATGLSKGFAFCEYL 908

Query: 89  DPKDAEKAINTLNGLRLQTKTIKVSYA 115
           DP   ++A   LNG++L  K + V  A
Sbjct: 909 DPSVTDQACAGLNGMQLGDKKLIVQRA 989

 Score = 38.9 bits (89), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 23/72 (31%), Positives = 34/72 (47%)
 Frame = +3

Query: 279 IFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 338
           IF+  L     E  + ++   FG + +  ++RD  T   KGF F    +      A A L
Sbjct: 765 IFMGGLPSYLSEDQMKELLLSFGPLKSFNLVRDNATGLSKGFAFCEYLDPSVTDQACAGL 944

Query: 339 NGYRLGDRVLQV 350
           NG +LGD+ L V
Sbjct: 945 NGMQLGDKKLIV 980
>12350
          Length = 975

 Score = 59.3 bits (142), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 27/114 (23%), Positives = 62/114 (54%)
 Frame = -2

Query: 39  TNLIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAIN 98
           ++LIV  LP   T+++L+S F   G++   ++ +D  TGQS G+GF+ + + +   K + 
Sbjct: 620 SDLIVLGLPWKSTEDDLRSYFSQFGDLLMVQVKKDPKTGQSKGFGFIRFAEYESQLKCMA 441

Query: 99  TLNGLRLQTKTIKVSYARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRII 152
             + +  +   +++  ++  +  + +  ++V      MT  +L Q FS++G ++
Sbjct: 440 QRHMIDGRWCDVRIPNSKEGAQQLMNRKIFVGRCTDDMTADDLRQFFSKFGEVV 279

 Score = 47.4 bits (111), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 23/56 (41%), Positives = 35/56 (62%)
 Frame = -2

Query: 118 SSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGISRGVGFIRF 173
           SS+  + ++L V GLP   T+ +L   FSQ+G ++  ++  D  TG S+G GFIRF
Sbjct: 641 SSSRQKCSDLIVLGLPWKSTEDDLRSYFSQFGDLLMVQVKKDPKTGQSKGFGFIRF 474

 Score = 34.3 bits (77), Expect = 0.090,   Method: Compositional matrix adjust.
 Identities = 18/58 (31%), Positives = 27/58 (46%)
 Frame = -2

Query: 279 IFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIA 336
           + V  L   + E  L   F  FG +  V+V +D  T + KGFGF+    Y+     +A
Sbjct: 614 LIVLGLPWKSTEDDLRSYFSQFGDLLMVQVKKDPKTGQSKGFGFIRFAEYESQLKCMA 441
>14258
          Length = 1063

 Score = 58.5 bits (140), Expect = 4e-09,   Method: Compositional matrix adjust.
 Identities = 33/76 (43%), Positives = 44/76 (57%)
 Frame = +2

Query: 284 LAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYRL 343
           LAP   +  L QMF PFG V + KV  D  TN  K FGFV+  +   A  AI+S+NG+++
Sbjct: 83  LAPGVGDQDLMQMFMPFGNVISAKVFIDKQTNLSKCFGFVSYDSPMSAQDAISSMNGFQI 262

Query: 344 GDRVLQVSFKTNKTHK 359
           G + L+V  K  K  K
Sbjct: 263 GMKRLKVQLKRPKNDK 310

 Score = 50.1 bits (118), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 24/65 (36%), Positives = 38/65 (58%)
 Frame = +2

Query: 53  EELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKV 112
           ++L  +F   G + S K+  DK T  S  +GFV+Y  P  A+ AI+++NG ++  K +KV
Sbjct: 104 QDLMQMFMPFGNVISAKVFIDKQTNLSKCFGFVSYDSPMSAQDAISSMNGFQIGMKRLKV 283

Query: 113 SYARP 117
              RP
Sbjct: 284 QLKRP 298

 Score = 48.1 bits (113), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 16/50 (32%), Positives = 35/50 (70%)
 Frame = +2

Query: 139 KELEQLFSQYGRIITSRILVDQVTGISRGVGFIRFDKRIEAEEAIKGLNG 188
           ++L Q+F  +G +I++++ +D+ T +S+  GF+ +D  + A++AI  +NG
Sbjct: 104 QDLMQMFMPFGNVISAKVFIDKQTNLSKCFGFVSYDSPMSAQDAISSMNG 253
>03406
          Length = 1292

 Score = 57.8 bits (138), Expect = 7e-09,   Method: Compositional matrix adjust.
 Identities = 36/142 (25%), Positives = 66/142 (46%)
 Frame = +3

Query: 33  NTEDSKTNLIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKD 92
           N +D K  + V  L      + L+  F   GE+ SC L  D  +G+S G+GFV + +   
Sbjct: 228 NEDDRK--IFVGGLSWETXSKHLREYFEKFGEVTSCTLKTDLDSGKSRGFGFVVFKEAAT 401

Query: 93  AEKAINTLNGLRLQTKTIKVSYARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRII 152
            +  +      +LQ + I    A P     +   ++V  L   + Q+++E  F+++G+++
Sbjct: 402 VDAVVKNKE-HKLQGRKIDPKPANPRKGMRK---IFVGKLDPGVPQEDVESYFAKFGKVV 569

Query: 153 TSRILVDQVTGISRGVGFIRFD 174
              +  D+V    R   F+ FD
Sbjct: 570 NVELPYDKVKDQRRAFCFVEFD 635

 Score = 38.1 bits (87), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 17/61 (27%), Positives = 30/61 (49%)
 Frame = +3

Query: 124 DANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGISRGVGFIRFDKRIEAEEAI 183
           D  ++V GL      K L + F ++G + +  +  D  +G SRG GF+ F +    +  +
Sbjct: 237 DRKIFVGGLSWETXSKHLREYFEKFGEVTSCTLKTDLDSGKSRGFGFVVFKEAATVDAVV 416

Query: 184 K 184
           K
Sbjct: 417 K 419

 Score = 35.8 bits (81), Expect = 0.029,   Method: Compositional matrix adjust.
 Identities = 21/58 (36%), Positives = 30/58 (51%)
 Frame = +3

Query: 279 IFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIA 336
           IFV  L+ +     L + F  FG VT+  +  D ++ K +GFGFV    + EAA   A
Sbjct: 246 IFVGGLSWETXSKHLREYFEKFGEVTSCTLKTDLDSGKSRGFGFVV---FKEAATVDA 410
>14637
          Length = 455

 Score = 57.8 bits (138), Expect = 7e-09,   Method: Compositional matrix adjust.
 Identities = 32/93 (34%), Positives = 49/93 (52%), Gaps = 1/93 (1%)
 Frame = -1

Query: 14  TANGPTTVNNNCSSPVDSGNTED-SKTNLIVNYLPQNMTQEELKSLFGSIGEIESCKLVR 72
           TA+ P   NN       +  +E    +NL + +LPQ    ++L  +F   G + S K+  
Sbjct: 281 TASFPNAFNNQMQQNAAAKQSEGPDGSNLFIYHLPQEFGDQDLMQMFMPFGNVISAKVFI 102

Query: 73  DKITGQSLGYGFVNYIDPKDAEKAINTLNGLRL 105
           DK T  S  +GFV+Y  P  A+ AI+++NG RL
Sbjct: 101 DKQTNLSKCFGFVSYDSPMSAQDAISSMNGFRL 3

 Score = 57.8 bits (138), Expect = 7e-09,   Method: Compositional matrix adjust.
 Identities = 20/64 (31%), Positives = 43/64 (67%)
 Frame = -1

Query: 125 ANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGISRGVGFIRFDKRIEAEEAIK 184
           +NL++  LP+    ++L Q+F  +G +I++++ +D+ T +S+  GF+ +D  + A++AI 
Sbjct: 203 SNLFIYHLPQEFGDQDLMQMFMPFGNVISAKVFIDKQTNLSKCFGFVSYDSPMSAQDAIS 24

Query: 185 GLNG 188
            +NG
Sbjct: 23  SMNG 12

 Score = 55.5 bits (132), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 30/68 (44%), Positives = 41/68 (60%)
 Frame = -1

Query: 276 GWCIFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAI 335
           G  +F+Y+L  +  +  L QMF PFG V + KV  D  TN  K FGFV+  +   A  AI
Sbjct: 206 GSNLFIYHLPQEFGDQDLMQMFMPFGNVISAKVFIDKQTNLSKCFGFVSYDSPMSAQDAI 27

Query: 336 ASLNGYRL 343
           +S+NG+RL
Sbjct: 26  SSMNGFRL 3
>01278
          Length = 1082

 Score = 55.8 bits (133), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 27/84 (32%), Positives = 46/84 (54%)
 Frame = +2

Query: 35  EDSKTNLIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAE 94
           +D    + V  L ++  + +L+ LF   G I    L +DK+TGQS G+ F+N+   +DA 
Sbjct: 623 KDEAATIRVTNLSEDTRESDLQELFRPFGPISRIYLAKDKVTGQSKGFAFINFHRREDAS 802

Query: 95  KAINTLNGLRLQTKTIKVSYARPS 118
           +AI  ++G       + V +A+PS
Sbjct: 803 RAIAGVSGFGYDHLILNVEWAKPS 874

 Score = 53.9 bits (128), Expect = 9e-08,   Method: Compositional matrix adjust.
 Identities = 25/74 (33%), Positives = 43/74 (58%)
 Frame = +2

Query: 279 IFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 338
           I V NL+ D  ES L ++F PFG ++ + + +D  T + KGF F+     ++A+ AIA +
Sbjct: 641 IRVTNLSEDTRESDLQELFRPFGPISRIYLAKDKVTGQSKGFAFINFHRREDASRAIAGV 820

Query: 339 NGYRLGDRVLQVSF 352
           +G+     +L V +
Sbjct: 821 SGFGYDHLILNVEW 862
>00302
          Length = 927

 Score = 51.2 bits (121), Expect = 6e-07,   Method: Compositional matrix adjust.
 Identities = 25/87 (28%), Positives = 45/87 (51%), Gaps = 1/87 (1%)
 Frame = -1

Query: 273 PGTGWCIFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAA 332
           P    C+ ++ L+    E  L ++FG +G ++ V+V+ D  T + +GF FV   + ++A 
Sbjct: 477 PDPNRCLGIFGLSLYTQERGLREVFGRYGHISEVQVVYDRQTGRSRGFAFVYFKSSEDAH 298

Query: 333 MAIASLNGYRLGDRVLQVSFK-TNKTH 358
            A    NG  +  R ++V F  T + H
Sbjct: 297 EAKDRCNGIEIDGRKIRVDFSITERAH 217

 Score = 40.8 bits (94), Expect = 8e-04,   Method: Compositional matrix adjust.
 Identities = 21/62 (33%), Positives = 33/62 (53%)
 Frame = -1

Query: 127 LYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGISRGVGFIRFDKRIEAEEAIKGL 186
           L + GL     ++ L ++F +YG I   +++ D+ TG SRG  F+ F    +A EA    
Sbjct: 459 LGIFGLSLYTQERGLREVFGRYGHISEVQVVYDRQTGRSRGFAFVYFKSSEDAHEAKDRC 280

Query: 187 NG 188
           NG
Sbjct: 279 NG 274
>02140
          Length = 1796

 Score = 49.7 bits (117), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 27/83 (32%), Positives = 45/83 (54%)
 Frame = +3

Query: 41  LIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTL 100
           L V  L    T E+L+ +F   G I SC+++RD  T +SL Y FV +  P+  E A   +
Sbjct: 807 LFVCKLNPVTTDEDLEMIFSRFGPITSCEVIRDHKTKESLQYAFVEFEKPEHCENAYFKM 986

Query: 101 NGLRLQTKTIKVSYARPSSASIR 123
           + + +  + I V +++ S + IR
Sbjct: 987 DNVLIDDRRIHVDFSQ-SVSKIR 1052
>13822
          Length = 963

 Score = 49.3 bits (116), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 26/67 (38%), Positives = 39/67 (58%)
 Frame = -1

Query: 290 ESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQ 349
           E+ L Q+ GPFG + +V++I  FN    KGFGFVT  +  EA  A   +NG  +  R ++
Sbjct: 303 EADLRQLLGPFGTILDVEII--FNERGSKGFGFVTFAHSAEAERARDKMNGTVVEGRKIE 130

Query: 350 VSFKTNK 356
           V+  T +
Sbjct: 129 VNNATAR 109

 Score = 39.7 bits (91), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 21/62 (33%), Positives = 33/62 (53%)
 Frame = -1

Query: 127 LYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGISRGVGFIRFDKRIEAEEAIKGL 186
           L+VS +P    + +L QL   +G I+   I+ ++    S+G GF+ F    EAE A   +
Sbjct: 336 LHVSNIPFRFREADLRQLLGPFGTILDVEIIFNERG--SKGFGFVTFAHSAEAERARDKM 163

Query: 187 NG 188
           NG
Sbjct: 162 NG 157

 Score = 39.3 bits (90), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 30/111 (27%), Positives = 55/111 (49%), Gaps = 5/111 (4%)
 Frame = -1

Query: 10  TCNNTANGPTTVNNN-----CSSPVDSGNTEDSKTNLIVNYLPQNMTQEELKSLFGSIGE 64
           T N T    T VN++        P  + + E  K  L V+ +P    + +L+ L G  G 
Sbjct: 441 TANGTVEQSTEVNSDGEVQGVQVPPQAISPEGPK-RLHVSNIPFRFREADLRQLLGPFGT 265

Query: 65  IESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYA 115
           I   +++ ++    S G+GFV +    +AE+A + +NG  ++ + I+V+ A
Sbjct: 264 ILDVEIIFNE--RGSKGFGFVTFAHSAEAERARDKMNGTVVEGRKIEVNNA 118
>30672
          Length = 877

 Score = 49.3 bits (116), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 54/239 (22%), Positives = 96/239 (40%), Gaps = 9/239 (3%)
 Frame = +3

Query: 127 LYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGISRGVGFIRF---DKRIEAEEAI 183
           L+V  LP   + ++L + F Q G + T+ ++  +  G  RG G+++F   +  I+A++ +
Sbjct: 18  LFVRNLPFETSNEKLLEAFEQVGPLKTAFVVAGKEPGKCRGFGYVQFSMLEDAIKAKDTV 197

Query: 184 KGLNGQKPPGATEPITVKFAN-NPSQKTNQAILSQLYQSPNRRYPGPLAQQAQRFRLDNL 242
              +G+K       I++ FA+   S KT Q   ++   +                     
Sbjct: 198 THCSGRK-------ISLSFADTKKSWKTKQKGGTETSDA--------------------- 293

Query: 243 LNMAYGVKSRFSPMTIDG----MTSLAGINIPGHPGTGWC-IFVYNLAPDADESILWQMF 297
             +  G K        DG             P       C + + NLA    E+ +   F
Sbjct: 294 --LGLGKKLPSQTAVTDGEPNPKPEKKKTKQPKQELGKRCRLIIRNLAFKCKEADIRSHF 467

Query: 298 GPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQVSFKTNK 356
           G FG ++ V +      ++ +GF FV  T    A  AI+ +NG  + DR + V +   K
Sbjct: 468 GKFGTISEVTIPLK-QGDRSRGFAFVQFTEVKAAQKAISDMNGTAIMDRPVAVDWAVAK 641

 Score = 40.0 bits (92), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 22/78 (28%), Positives = 40/78 (51%)
 Frame = +3

Query: 38  KTNLIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAI 97
           +  LI+  L     + +++S FG  G I    +   K   +S G+ FV + + K A+KAI
Sbjct: 402 RCRLIIRNLAFKCKEADIRSHFGKFGTISEVTIPL-KQGDRSRGFAFVQFTEVKAAQKAI 578

Query: 98  NTLNGLRLQTKTIKVSYA 115
           + +NG  +  + + V +A
Sbjct: 579 SDMNGTAIMDRPVAVDWA 632
>15371
          Length = 383

 Score = 48.9 bits (115), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 19/74 (25%), Positives = 41/74 (55%)
 Frame = -2

Query: 101 NGLRLQTKTIKVSYARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQ 160
           N    Q +  + + A   S     ANL++  LP+    ++L Q+F  +G ++++++ +D+
Sbjct: 229 NAFNPQAQMQQANSAGKHSEGPDGANLFIYHLPQEFGDQDLMQMFMPFGNVVSAKVFIDK 50

Query: 161 VTGISRGVGFIRFD 174
            T +S+  GF+ +D
Sbjct: 49  QTNLSKCFGFVSYD 8

 Score = 44.3 bits (103), Expect = 8e-05,   Method: Compositional matrix adjust.
 Identities = 22/49 (44%), Positives = 29/49 (59%)
 Frame = -2

Query: 276 GWCIFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVT 324
           G  +F+Y+L  +  +  L QMF PFG V + KV  D  TN  K FGFV+
Sbjct: 160 GANLFIYHLPQEFGDQDLMQMFMPFGNVVSAKVFIDKQTNLSKCFGFVS 14

 Score = 40.4 bits (93), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 19/52 (36%), Positives = 28/52 (53%)
 Frame = -2

Query: 39  TNLIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDP 90
            NL + +LPQ    ++L  +F   G + S K+  DK T  S  +GFV+Y  P
Sbjct: 157 ANLFIYHLPQEFGDQDLMQMFMPFGNVVSAKVFIDKQTNLSKCFGFVSYDSP 2
>00029
          Length = 2204

 Score = 48.5 bits (114), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 28/76 (36%), Positives = 39/76 (51%)
 Frame = -3

Query: 279  IFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 338
            IF+ NL  D D   L  +F  +G+V    V+        K FGFV M    EA  AI++L
Sbjct: 2130 IFIGNLGDDTDPEELRALFEKYGSVAECDVL--------KNFGFVHMVKKGEADDAISNL 1975

Query: 339  NGYRLGDRVLQVSFKT 354
            NGY +G + ++V   T
Sbjct: 1974 NGYNIGGQRMRVELST 1927

 Score = 36.6 bits (83), Expect = 0.014,   Method: Compositional matrix adjust.
 Identities = 18/73 (24%), Positives = 38/73 (52%)
 Frame = -3

Query: 41   LIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTL 100
            + +  L  +   EEL++LF   G +  C ++++        +GFV+ +   +A+ AI+ L
Sbjct: 2130 IFIGNLGDDTDPEELRALFEKYGSVAECDVLKN--------FGFVHMVKKGEADDAISNL 1975

Query: 101  NGLRLQTKTIKVS 113
            NG  +  + ++V 
Sbjct: 1974 NGYNIGGQRMRVE 1936

 Score = 33.5 bits (75), Expect = 0.13,   Method: Compositional matrix adjust.
 Identities = 18/62 (29%), Positives = 30/62 (48%)
 Frame = -3

Query: 127  LYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGISRGVGFIRFDKRIEAEEAIKGL 186
            +++  L      +EL  LF +YG +    +L        +  GF+   K+ EA++AI  L
Sbjct: 2130 IFIGNLGDDTDPEELRALFEKYGSVAECDVL--------KNFGFVHMVKKGEADDAISNL 1975

Query: 187  NG 188
            NG
Sbjct: 1974 NG 1969
>32733
          Length = 709

 Score = 48.1 bits (113), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 26/74 (35%), Positives = 39/74 (52%), Gaps = 1/74 (1%)
 Frame = +1

Query: 132 LPKTMTQKELEQLFSQYGRIITSRILVDQVTGISRGVGFIRFDKRIEAEEAIKGL-NGQK 190
           L K +++ ++  LF  +G I    +L D   G SRG  FI F  R  A  +IKG+ + Q 
Sbjct: 487 LSKKLSENDVRMLFESFGSIDDCTVLRDS-NGTSRGCAFITFASRQCAMNSIKGMHHSQT 663

Query: 191 PPGATEPITVKFAN 204
             G + P+ VK A+
Sbjct: 664 MEGCSSPLVVKMAD 705
>02415
          Length = 2763

 Score = 47.8 bits (112), Expect = 7e-06,   Method: Compositional matrix adjust.
 Identities = 22/61 (36%), Positives = 33/61 (54%)
 Frame = -1

Query: 127  LYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGISRGVGFIRFDKRIEAEEAIKGL 186
            ++V GLP   T   L + F ++G I  + ++ D+ TG SRG GF+    R  A+ A K  
Sbjct: 1920 IFVGGLPYHTTDHSLREYFDKFGDIDEAVVITDRQTGKSRGYGFVTMADRTGADRACKDP 1741

Query: 187  N 187
            N
Sbjct: 1740 N 1738

 Score = 38.5 bits (88), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 29/88 (32%), Positives = 38/88 (43%), Gaps = 11/88 (12%)
 Frame = -1

Query: 251  SRFSPMTID----------GMTSLAGINIPGHPGTGWC-IFVYNLAPDADESILWQMFGP 299
            SRF P T+             TS+    I G   T +  IFV  L     +  L + F  
Sbjct: 2037 SRFKPPTVKISALYINTNMATTSINPALITGQKDTTYTKIFVGGLPYHTTDHSLREYFDK 1858

Query: 300  FGAVTNVKVIRDFNTNKCKGFGFVTMTN 327
            FG +    VI D  T K +G+GFVTM +
Sbjct: 1857 FGDIDEAVVITDRQTGKSRGYGFVTMAD 1774
>12506
          Length = 1056

 Score = 47.4 bits (111), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 21/68 (30%), Positives = 39/68 (57%)
 Frame = -3

Query: 285  APDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYRLG 344
            A + D+ +L   F PFG + ++++  D+ T K +GF F+     ++AA AI ++N   L 
Sbjct: 1039 AGEVDDKVLHAAFLPFGDIVDIQIPLDYETEKHRGFAFIEFELAEDAAAAIDNMNESELF 860

Query: 345  DRVLQVSF 352
             R ++V+ 
Sbjct: 859  GRTIRVNL 836
>01937
          Length = 1320

 Score = 46.6 bits (109), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 27/98 (27%), Positives = 46/98 (46%), Gaps = 4/98 (4%)
 Frame = -1

Query: 81   GYGFVNYIDPKDAEKAI----NTLNGLRLQTKTIKVSYARPSSASIRDANLYVSGLPKTM 136
            G+GFV Y DP + +  +    + ++   + TKT K+               +V GL  + 
Sbjct: 1314 GFGFVTYKDPSNVDNVLANGPHCIDSKTMVTKTSKI---------------FVGGLSSST 1180

Query: 137  TQKELEQLFSQYGRIITSRILVDQVTGISRGVGFIRFD 174
            T ++ +  F  YG I  + ++ D+VT   RG  F+ FD
Sbjct: 1179 TVEDXKNYFKAYGTIEEATLMFDKVTSRHRGFAFVTFD 1066
>23322
          Length = 471

 Score = 45.4 bits (106), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 23/69 (33%), Positives = 36/69 (52%), Gaps = 4/69 (5%)
 Frame = -2

Query: 279 IFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAI--- 335
           +FV  +  D  E ++   F  FG +T V +I+D  T K +GF FVT  ++D    A+   
Sbjct: 404 MFVGGVKEDTTEDMIRDTFNEFGEITGVDLIQDKGTGKNRGFCFVTFGDHDSVDKAVLKK 225

Query: 336 -ASLNGYRL 343
              LNG ++
Sbjct: 224 RHDLNGRQV 198
>10194
          Length = 1278

 Score = 44.7 bits (104), Expect = 6e-05,   Method: Compositional matrix adjust.
 Identities = 24/72 (33%), Positives = 38/72 (52%)
 Frame = -3

Query: 279 IFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 338
           +FV NL  D +E  +   F   G V N++V+RD  TN  KG  ++   + D  ++A+  L
Sbjct: 400 VFVGNLPFDIEEESVRSHFEDCGDVENIRVVRDRKTNLGKGICYILFKSADSVSLAL-KL 224

Query: 339 NGYRLGDRVLQV 350
           N   L  R ++V
Sbjct: 223 NNSELEKRQIRV 188
>31310
          Length = 469

 Score = 44.3 bits (103), Expect = 8e-05,   Method: Compositional matrix adjust.
 Identities = 25/77 (32%), Positives = 42/77 (54%)
 Frame = -3

Query: 279 IFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 338
           I+V ++  +  E  + Q F PFG + +V +  D  TNK KGF F+     + A +A+  +
Sbjct: 317 IYVGSINFEIREDTIKQAFLPFGPIKSVNLSWDPITNKHKGFSFIEYDVPEAAQLALEQM 138

Query: 339 NGYRLGDRVLQVSFKTN 355
           NG  +G R ++V   +N
Sbjct: 137 NGVMIGGRNIKVGRPSN 87

 Score = 42.0 bits (97), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 23/70 (32%), Positives = 38/70 (54%)
 Frame = -3

Query: 49  NMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTK 108
            + ++ +K  F   G I+S  L  D IT +  G+ F+ Y  P+ A+ A+  +NG+ +  +
Sbjct: 293 EIREDTIKQAFLPFGPIKSVNLSWDPITNKHKGFSFIEYDVPEAAQLALEQMNGVMIGGR 114

Query: 109 TIKVSYARPS 118
            IKV   RPS
Sbjct: 113 NIKV--GRPS 90
>00738
          Length = 1559

 Score = 44.3 bits (103), Expect = 8e-05,   Method: Compositional matrix adjust.
 Identities = 26/89 (29%), Positives = 43/89 (48%)
 Frame = -2

Query: 39   TNLIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAIN 98
            T + V  L  + +  E++  F   G+I    + R + T       FV Y   +DAEKAI 
Sbjct: 1267 TRIHVGSLSSSTSTREIREEFKRFGDIIDLWMPRTQPT-----IAFVVYRYEEDAEKAIR 1103

Query: 99   TLNGLRLQTKTIKVSYARPSSASIRDANL 127
             ++G  +  + ++VS ARP S  +R  + 
Sbjct: 1102 RMDGESMHGRRVRVSLARPRSQGVRGGSF 1016
>24983
          Length = 433

 Score = 44.3 bits (103), Expect = 9e-05,   Method: Compositional matrix adjust.
 Identities = 21/59 (35%), Positives = 31/59 (52%)
 Frame = -2

Query: 129 VSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGISRGVGFIRFDKRIEAEEAIKGLN 187
           + GLP   T   L + F ++G I  + ++ D+ TG SRG GF+    R  A+ A K  N
Sbjct: 303 LGGLPYHTTDHSLREYFDKFGDIDEAVVITDRQTGKSRGYGFVTMADRTGADRACKDPN 127

 Score = 34.7 bits (78), Expect = 0.069,   Method: Compositional matrix adjust.
 Identities = 15/35 (42%), Positives = 20/35 (57%)
 Frame = -2

Query: 293 LWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTN 327
           L + F  FG +    VI D  T K +G+GFVTM +
Sbjct: 267 LREYFDKFGDIDEAVVITDRQTGKSRGYGFVTMAD 163
>01065
          Length = 1033

 Score = 43.9 bits (102), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 26/89 (29%), Positives = 43/89 (48%)
 Frame = +2

Query: 39  TNLIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAIN 98
           T + V  L  + +  E++  F   G+I    + R + T       FV Y   +DAEKAI 
Sbjct: 14  TRIHVGSLSSSTSTREIREEFKRFGDIIDLWMPRTQPT-----IAFVVYRYEEDAEKAIR 178

Query: 99  TLNGLRLQTKTIKVSYARPSSASIRDANL 127
            ++G  +  + ++VS ARP S  +R  + 
Sbjct: 179 RMDGESMHGRRVRVSLARPRSQGVRGGSF 265
>03059
          Length = 1154

 Score = 42.4 bits (98), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 22/73 (30%), Positives = 42/73 (57%), Gaps = 1/73 (1%)
 Frame = -2

Query: 39  TNLIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKI-TGQSLGYGFVNYIDPKDAEKAI 97
           T + V  L +N+ ++ ++ +F   G I+   L  D+I    S G+ +V Y +P+DAEKA+
Sbjct: 670 TKVHVGRLTRNVNKDHIQEIFSLYGTIKFIDLPNDRIHPNTSKGHAYVEYENPEDAEKAV 491

Query: 98  NTLNGLRLQTKTI 110
             ++G ++  + I
Sbjct: 490 KYMDGGQIDGQEI 452
>31618
          Length = 716

 Score = 42.4 bits (98), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 34/97 (35%), Positives = 47/97 (48%), Gaps = 9/97 (9%)
 Frame = +1

Query: 105 LQTKTIKVSYARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGI 164
           LQ    K+   R +S  + +  L+V GL    T+KEL   F +YG I +  +  D  TG 
Sbjct: 235 LQMAAQKMQPLRVTSVMMTE-KLFVGGLSWETTEKELRDHFGKYGEIESINVKTDPQTGR 411

Query: 165 SRGVGFIRF------DKRIEAEEAI---KGLNGQKPP 192
           SRG  FI F      D+   AEE I   K ++ +K P
Sbjct: 412 SRGFAFIVFTNTEAIDQVSAAEEHIINSKKVDPKKKP 522
>33516
          Length = 449

 Score = 42.4 bits (98), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 19/49 (38%), Positives = 28/49 (57%)
 Frame = +1

Query: 125 ANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGISRGVGFIRF 173
             ++V GL     Q  L+  FSQ+G I    ++++Q TG SRG GF+ F
Sbjct: 154 GKIFVGGLSWDTDQDSLQGYFSQFGEITDCIVMMNQQTGKSRGFGFVSF 300

 Score = 41.6 bits (96), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 18/59 (30%), Positives = 34/59 (57%)
 Frame = +1

Query: 41  LIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINT 99
           + V  L  +  Q+ L+  F   GEI  C ++ ++ TG+S G+GFV++ DP   +  +++
Sbjct: 160 IFVGGLSWDTDQDSLQGYFSQFGEITDCIVMMNQQTGKSRGFGFVSFKDPSTVDVILSS 336

 Score = 38.5 bits (88), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 19/49 (38%), Positives = 28/49 (57%)
 Frame = +1

Query: 279 IFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTN 327
           IFV  L+ D D+  L   F  FG +T+  V+ +  T K +GFGFV+  +
Sbjct: 160 IFVGGLSWDTDQDSLQGYFSQFGEITDCIVMMNQQTGKSRGFGFVSFKD 306
>26197
          Length = 1365

 Score = 41.2 bits (95), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 23/93 (24%), Positives = 43/93 (46%)
 Frame = -2

Query: 92   DAEKAINTLNGLRLQTKTIKVSYARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRI 151
            D+E  ++T +G           Y R  +    D  ++V GL    + K L + F ++G +
Sbjct: 1361 DSEAVVSTQSG----------HYGREENED--DRKIFVGGLSWETSSKHLREYFEKFGEV 1218

Query: 152  ITSRILVDQVTGISRGVGFIRFDKRIEAEEAIK 184
             +  +  D  +G SRG GF+ F + +  +  +K
Sbjct: 1217 TSCTLKTDLDSGKSRGFGFVVFKEAVTVDAVVK 1119

 Score = 36.2 bits (82), Expect = 0.020,   Method: Compositional matrix adjust.
 Identities = 19/55 (34%), Positives = 29/55 (52%)
 Frame = -2

Query: 33   NTEDSKTNLIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNY 87
            N +D K  + V  L    + + L+  F   GE+ SC L  D  +G+S G+GFV +
Sbjct: 1310 NEDDRK--IFVGGLSWETSSKHLREYFEKFGEVTSCTLKTDLDSGKSRGFGFVVF 1152

 Score = 35.8 bits (81), Expect = 0.028,   Method: Compositional matrix adjust.
 Identities = 17/47 (36%), Positives = 25/47 (53%)
 Frame = -2

Query: 279  IFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTM 325
            IFV  L+ +     L + F  FG VT+  +  D ++ K +GFGFV  
Sbjct: 1292 IFVGGLSWETSSKHLREYFEKFGEVTSCTLKTDLDSGKSRGFGFVVF 1152
>32386
          Length = 674

 Score = 41.2 bits (95), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 18/58 (31%), Positives = 32/58 (55%)
 Frame = +1

Query: 279 IFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIA 336
           +F+  L+ + DE  L   F  +G + +  V+RD N+ + +GFGF+T  + +    A A
Sbjct: 307 LFIGGLSYETDEDSLRSHFETWGEIVDCIVMRDSNSKRSRGFGFITYKDAESIDQAQA 480

 Score = 40.4 bits (93), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 21/72 (29%), Positives = 39/72 (54%), Gaps = 4/72 (5%)
 Frame = +1

Query: 41  LIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAI--- 97
           L +  L     ++ L+S F + GEI  C ++RD  + +S G+GF+ Y D +  ++A    
Sbjct: 307 LFIGGLSYETDEDSLRSHFETWGEIVDCIVMRDSNSKRSRGFGFITYKDAESIDQAQANR 486

Query: 98  -NTLNGLRLQTK 108
            + ++G  + TK
Sbjct: 487 PHKIDGREVDTK 522

 Score = 32.0 bits (71), Expect = 0.44,   Method: Compositional matrix adjust.
 Identities = 31/129 (24%), Positives = 58/129 (44%), Gaps = 5/129 (3%)
 Frame = +1

Query: 117 PSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGISRGVGFIRFDKR 176
           P++   R   L++ GL     +  L   F  +G I+   ++ D  +  SRG GFI +   
Sbjct: 283 PNAEQFR--KLFIGGLSYETDEDSLRSHFETWGEIVDCIVMRDSNSKRSRGFGFITY--- 447

Query: 177 IEAEEAIKGLNGQKPPGAT-EPITVKFANNPSQKTNQAILSQLYQSPNRRYPGPLA---- 231
            +  E+I      +P       +  K A  P +++ +   S++ QS  + + G L+    
Sbjct: 448 -KDAESIDQAQANRPHKIDGREVDTKRA-MPREESGR---SEVQQSVKKMFVGSLSCKLG 612

Query: 232 QQAQRFRLD 240
           + AQ ++LD
Sbjct: 613 RAAQVWQLD 639
>03200
          Length = 657

 Score = 40.4 bits (93), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 24/78 (30%), Positives = 38/78 (48%)
 Frame = -1

Query: 273 PGTGWCIFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAA 332
           P  G  ++V+ +     E IL   F  FG + N+ + R+ N       GFVT    + A 
Sbjct: 498 PSKGHTVYVHGIG--VTEDILKSAFSNFGNIVNINIERERNN------GFVTFEKMESAD 343

Query: 333 MAIASLNGYRLGDRVLQV 350
            AIA++NG  + +  L+V
Sbjct: 342 QAIANMNGSMISNVQLKV 289

 Score = 36.6 bits (83), Expect = 0.016,   Method: Compositional matrix adjust.
 Identities = 30/102 (29%), Positives = 47/102 (46%), Gaps = 2/102 (1%)
 Frame = -1

Query: 50  MTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKT 109
           +T++ LKS F + G I +  + R++        GFV +   + A++AI  +NG  +    
Sbjct: 459 VTEDILKSAFSNFGNIVNINIERER------NNGFVTFEKMESADQAIANMNGSMISNVQ 298

Query: 110 IKVSYAR--PSSASIRDANLYVSGLPKTMTQKELEQLFSQYG 149
           +KV  AR  PS  S+ D        P T T   +    SQ G
Sbjct: 297 LKVMMARRQPSFDSVND--------PSTTTWSSIAASHSQKG 196

 Score = 32.7 bits (73), Expect = 0.22,   Method: Compositional matrix adjust.
 Identities = 31/114 (27%), Positives = 51/114 (44%), Gaps = 8/114 (7%)
 Frame = -1

Query: 127 LYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGISRGVGFIRFDKRIEAEEAIKGL 186
           +YV G+   +T+  L+  FS +G I+   I  +      R  GF+ F+K   A++AI  +
Sbjct: 480 VYVHGI--GVTEDILKSAFSNFGNIVNINIERE------RNNGFVTFEKMESADQAIANM 325

Query: 187 NGQ-------KPPGATEPITVKFANNPSQKTNQAILSQLYQS-PNRRYPGPLAQ 232
           NG        K   A    +    N+PS  T  +I +   Q  P+R+    + Q
Sbjct: 324 NGSMISNVQLKVMMARRQPSFDSVNDPSTTTWSSIAASHSQKGPSRKEDRDMVQ 163
>31938
          Length = 746

 Score = 40.4 bits (93), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 20/74 (27%), Positives = 41/74 (55%)
 Frame = +3

Query: 41  LIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTL 100
           +++  +P + T + L+  F  +G+++  ++  + +       G V +   +DAE AI  +
Sbjct: 267 IVIKNVPLSCTWQTLRDKFRDVGDVKFAEIRGNDV-------GVVRFFKERDAELAIALM 425

Query: 101 NGLRLQTKTIKVSY 114
           +G RL  +TIKV+Y
Sbjct: 426 DGSRLDGRTIKVTY 467
>28652
          Length = 918

 Score = 40.4 bits (93), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 21/72 (29%), Positives = 38/72 (52%)
 Frame = -2

Query: 272 HPGTGWCIFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEA 331
            PG+G  +F   +  D  E  L  +F   G + +++++ D  +N  +G+ FVT T  + A
Sbjct: 746 QPGSGHEVFCGKIPRDIFEDELIPLFEDCGTIWDLRLMMDPVSNLNRGYCFVTYTTKEAA 567

Query: 332 AMAIASLNGYRL 343
           A A+   +GY +
Sbjct: 566 AEAVKQHDGYEI 531

 Score = 40.4 bits (93), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 39/160 (24%), Positives = 73/160 (45%), Gaps = 10/160 (6%)
 Frame = -2

Query: 41  LIVNYLPQNMTQEELKSLFGSIGEIESCKLV---RDKITGQSLGYGFVNYIDPKDAEKAI 97
           L V  +P++ T+EE+   F    E     +V    D    ++ G+ F+ Y   K+A  A 
Sbjct: 482 LFVGNIPKSKTKEEILKEFEKHSEGLMDVIVYGSADNPKLKNRGFAFLEYDTHKNASAAK 303

Query: 98  N--TLNGLRLQTKTIKVSYA----RPSSASIRDAN-LYVSGLPKTMTQKELEQLFSQYGR 150
              T    R+    + V +A     P+  ++     LYV  L   +T+ +L++ F  YG+
Sbjct: 302 RRFTTGRFRVWQCDVIVDWADLQEEPNEETMSKVKVLYVRNLTGDVTEDDLKEKFGAYGK 123

Query: 151 IITSRILVDQVTGISRGVGFIRFDKRIEAEEAIKGLNGQK 190
           +   + + D         GF+ ++ R +A +A+  L+G+K
Sbjct: 122 VERVKKIKD--------YGFVHYEDREDALKALDDLHGEK 27
>23720
          Length = 739

 Score = 40.0 bits (92), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 22/81 (27%), Positives = 39/81 (48%)
 Frame = -1

Query: 39  TNLIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAIN 98
           T + +  LP    +++++  F   G +    L          GYGFV + D +DA+ A+ 
Sbjct: 685 TRVYIGRLPYQAREKDIERFFRGYGRVNDIML--------KNGYGFVEFEDFRDADDAVY 530

Query: 99  TLNGLRLQTKTIKVSYARPSS 119
            LNG  L  + + + +AR +S
Sbjct: 529 ELNGKDLCGERVIIEHARGTS 467

 Score = 38.9 bits (89), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 23/81 (28%), Positives = 43/81 (53%)
 Frame = -1

Query: 127 LYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGISRGVGFIRFDKRIEAEEAIKGL 186
           +Y+  LP    +K++E+ F  YGR+  + I+      +  G GF+ F+   +A++A+  L
Sbjct: 679 VYIGRLPYQAREKDIERFFRGYGRV--NDIM------LKNGYGFVEFEDFRDADDAVYEL 524

Query: 187 NGQKPPGATEPITVKFANNPS 207
           NG+   G  E + ++ A   S
Sbjct: 523 NGKDLCG--ERVIIEHARGTS 467

 Score = 30.0 bits (66), Expect = 1.4,   Method: Compositional matrix adjust.
 Identities = 20/74 (27%), Positives = 36/74 (48%), Gaps = 1/74 (1%)
 Frame = -1

Query: 276 GWCIFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAI 335
           G  +++  L   A E  + + F  +G V ++ +          G+GFV   ++ +A  A+
Sbjct: 688 GTRVYIGRLPYQAREKDIERFFRGYGRVNDIML--------KNGYGFVEFEDFRDADDAV 533

Query: 336 ASLNGYRL-GDRVL 348
             LNG  L G+RV+
Sbjct: 532 YELNGKDLCGERVI 491
>09968
          Length = 2913

 Score = 40.0 bits (92), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 25/78 (32%), Positives = 36/78 (46%)
 Frame = -1

Query: 40   NLIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINT 99
            NL V+ L  +    +LKSLFG  G++   K+V +  +   L +GFV      +  K I  
Sbjct: 1389 NLWVSGLSSSTRATDLKSLFGKHGKVIGAKVVTNTRSPGRLCFGFVTMASADETTKCIQH 1210

Query: 100  LNGLRLQTKTIKVSYARP 117
            L+   L  K I V    P
Sbjct: 1209 LHRTELHGKMISVERFSP 1156

 Score = 37.7 bits (86), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 21/72 (29%), Positives = 34/72 (47%)
 Frame = -1

Query: 279  IFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 338
            ++V  L+     + L  +FG  G V   KV+ +  +     FGFVTM + DE    I  L
Sbjct: 1386 LWVSGLSSSTRATDLKSLFGKHGKVIGAKVVTNTRSPGRLCFGFVTMASADETTKCIQHL 1207

Query: 339  NGYRLGDRVLQV 350
            +   L  +++ V
Sbjct: 1206 HRTELHGKMISV 1171
>04988
          Length = 705

 Score = 40.0 bits (92), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 22/81 (27%), Positives = 39/81 (48%)
 Frame = -3

Query: 39  TNLIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAIN 98
           T + +  LP    +++++  F   G +    L          GYGFV + D +DA+ A+ 
Sbjct: 652 TRVYIGRLPYQAREKDIERFFRGYGRVNDIML--------KNGYGFVEFEDFRDADDAVY 497

Query: 99  TLNGLRLQTKTIKVSYARPSS 119
            LNG  L  + + + +AR +S
Sbjct: 496 ELNGKDLCGERVIIEHARGTS 434

 Score = 38.5 bits (88), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 23/81 (28%), Positives = 43/81 (53%)
 Frame = -3

Query: 127 LYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGISRGVGFIRFDKRIEAEEAIKGL 186
           +Y+  LP    +K++E+ F  YGR+  + I+      +  G GF+ F+   +A++A+  L
Sbjct: 646 VYIGRLPYQAREKDIERFFRGYGRV--NDIM------LKNGYGFVEFEDFRDADDAVYEL 491

Query: 187 NGQKPPGATEPITVKFANNPS 207
           NG+   G  E + ++ A   S
Sbjct: 490 NGKDLCG--ERVIIEHARGTS 434

 Score = 30.4 bits (67), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 20/74 (27%), Positives = 36/74 (48%), Gaps = 1/74 (1%)
 Frame = -3

Query: 276 GWCIFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAI 335
           G  +++  L   A E  + + F  +G V ++ +          G+GFV   ++ +A  A+
Sbjct: 655 GTRVYIGRLPYQAREKDIERFFRGYGRVNDIML--------KNGYGFVEFEDFRDADDAV 500

Query: 336 ASLNGYRL-GDRVL 348
             LNG  L G+RV+
Sbjct: 499 YELNGKDLCGERVI 458
>00817
          Length = 2606

 Score = 39.7 bits (91), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 16/49 (32%), Positives = 26/49 (53%)
 Frame = -2

Query: 279  IFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTN 327
            +F+  + PD DES L   F  +G +    V++D  T + + F F+T  N
Sbjct: 2545 VFIGGMHPDTDESSLRSYFEKYGDIRECIVVKDPATKRSRCFSFITFGN 2399
>19733
          Length = 723

 Score = 38.9 bits (89), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 46/206 (22%), Positives = 81/206 (39%), Gaps = 15/206 (7%)
 Frame = +3

Query: 149 GRIITSRILVDQVTGISRGVGFIRFDKRIEAEEAIKGLNGQKPPGAT----EPITVKFAN 204
           G +   R+++D+VTG SRG  F++F ++  A++ +         G       P+ V  A 
Sbjct: 3   GELAYVRLVIDKVTGQSRGTAFVQFKEKDAADQCLANXQDTTRGGGLRVQGRPLYVVAAV 182

Query: 205 NPSQKTNQAILSQLYQSPNRRYPGPLAQQAQRFRLDNLLNMAYGVKSRFSPMTIDGMTSL 264
           + +Q   Q    +  +  + R      +   R        M+    ++   + +     L
Sbjct: 183 SRTQAQTQKEADKSKEQKDNRNLFLAREGLIRAGTQAAEGMSQEDINKRMKVEMVKREKL 362

Query: 265 AGINIPGHPGTGWCIFVYNLAPDADESILWQMFGPF-----GAVTNVKVIRDF------N 313
             INI     T  C  V+NL P  DE  L  +           +T  +V+RD        
Sbjct: 363 KNINIFV-SSTRLC--VHNLLPSVDEKQLKTVVRKIVDDSTMKITECRVMRDLARTKQSG 533

Query: 314 TNKCKGFGFVTMTNYDEAAMAIASLN 339
            +K  G+ FV  + ++ A  A+  LN
Sbjct: 534 QSKSLGYAFVNFSTHEHALKALRGLN 611

 Score = 38.1 bits (87), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 27/76 (35%), Positives = 43/76 (56%), Gaps = 11/76 (14%)
 Frame = +3

Query: 37  SKTNLIVNYLPQNMTQEELKSLFGSIGE-----IESCKLVRD----KITGQS--LGYGFV 85
           S T L V+ L  ++ +++LK++   I +     I  C+++RD    K +GQS  LGY FV
Sbjct: 384 SSTRLCVHNLLPSVDEKQLKTVVRKIVDDSTMKITECRVMRDLARTKQSGQSKSLGYAFV 563

Query: 86  NYIDPKDAEKAINTLN 101
           N+   + A KA+  LN
Sbjct: 564 NFSTHEHALKALRGLN 611

 Score = 33.9 bits (76), Expect = 0.092,   Method: Compositional matrix adjust.
 Identities = 26/91 (28%), Positives = 46/91 (50%), Gaps = 8/91 (8%)
 Frame = +3

Query: 63  GEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLN------GLRLQTKTIKV--SY 114
           GE+   +LV DK+TGQS G  FV + +   A++ +          GLR+Q + + V  + 
Sbjct: 3   GELAYVRLVIDKVTGQSRGTAFVQFKEKDAADQCLANXQDTTRGGGLRVQGRPLYVVAAV 182

Query: 115 ARPSSASIRDANLYVSGLPKTMTQKELEQLF 145
           +R  + + ++A+       K+  QK+   LF
Sbjct: 183 SRTQAQTQKEAD-------KSKEQKDNRNLF 254
>16016
          Length = 1364

 Score = 38.5 bits (88), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 16/49 (32%), Positives = 26/49 (53%)
 Frame = -2

Query: 279  IFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTN 327
            +F+  + PD DES L   F  +G +    V++D  T + + F F+T  N
Sbjct: 1303 VFIGGMHPDTDESSLRSYFEKYGDIRECIVVKDPATKRSRCFSFITFGN 1157
>24794
          Length = 622

 Score = 38.5 bits (88), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 17/44 (38%), Positives = 26/44 (59%)
 Frame = -2

Query: 84  FVNYIDPKDAEKAINTLNGLRLQTKTIKVSYARPSSASIRDANL 127
           FV Y   +DAEKAI  ++G  +  + ++VS ARP S  +R  + 
Sbjct: 489 FVVYRYEEDAEKAIRRMDGESMHGRRVRVSLARPRSQGVRGGSF 358
>31265
          Length = 540

 Score = 38.1 bits (87), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 25/80 (31%), Positives = 39/80 (48%), Gaps = 3/80 (3%)
 Frame = +2

Query: 41  LIVNYLPQNMTQEELKSLFGSIG---EIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAI 97
           L V  L    T+E LK +F       EIE  K +RD        Y FV++   +DA KA+
Sbjct: 164 LXVRNLMLTTTEETLKDVFSRAAGGREIERVKKIRD--------YAFVHFRSREDAIKAM 319

Query: 98  NTLNGLRLQTKTIKVSYARP 117
           +  +G  ++   ++V  A+P
Sbjct: 320 DVTDGSTIEGSQVEVVLAKP 379
>15503
          Length = 570

 Score = 37.7 bits (86), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 24/93 (25%), Positives = 44/93 (47%)
 Frame = +1

Query: 260 GMTSLAGINIPGHPGTGWCIFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKG 319
            M+    + +P  P     ++V NL        ++ +FG +GA+  ++V    NT + KG
Sbjct: 103 AMSKKGNVRLP--PEVNRVLYVKNLPYKITAEEMYDIFGKYGAIRQIRV---GNTPETKG 267

Query: 320 FGFVTMTNYDEAAMAIASLNGYRLGDRVLQVSF 352
             FV   +  +A  A   L+G+ + +R L V +
Sbjct: 268 TAFVVYEDIFDAKNACDHLSGFNVCNRYLVVLY 366

 Score = 35.0 bits (79), Expect = 0.044,   Method: Compositional matrix adjust.
 Identities = 19/62 (30%), Positives = 33/62 (53%)
 Frame = +1

Query: 127 LYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGISRGVGFIRFDKRIEAEEAIKGL 186
           LYV  LP  +T +E+  +F +YG I   R+     T  ++G  F+ ++   +A+ A   L
Sbjct: 154 LYVKNLPYKITAEEMYDIFGKYGAIRQIRV---GNTPETKGTAFVVYEDIFDAKNACDHL 324

Query: 187 NG 188
           +G
Sbjct: 325 SG 330
>02347
          Length = 928

 Score = 37.4 bits (85), Expect = 0.009,   Method: Compositional matrix adjust.
 Identities = 18/65 (27%), Positives = 34/65 (52%)
 Frame = -3

Query: 124 DANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGISRGVGFIRFDKRIEAEEAI 183
           +  +YV  LP   ++KE+E+ F+ YG +         V     G  F+ F+   +A++A+
Sbjct: 749 EGKIYVGDLPPDASEKEVERAFNYYGHLRNV-----WVARNPPGFAFVEFEDTRDADDAV 585

Query: 184 KGLNG 188
           + L+G
Sbjct: 584 RALDG 570
>25632
          Length = 864

 Score = 37.4 bits (85), Expect = 0.009,   Method: Compositional matrix adjust.
 Identities = 20/57 (35%), Positives = 29/57 (50%)
 Frame = -2

Query: 300 FGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQVSFKTNK 356
           +G V    V+        K +GFV M    EA+ AI +LNGY +  + ++V   TNK
Sbjct: 698 YGTVEECDVL--------KNYGFVHMPTKSEASAAITNLNGYNIKGQRMRVELSTNK 552
>39789
          Length = 361

 Score = 36.2 bits (82), Expect = 0.022,   Method: Compositional matrix adjust.
 Identities = 26/79 (32%), Positives = 43/79 (54%), Gaps = 1/79 (1%)
 Frame = +1

Query: 278 CIFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIAS 337
            +FV NL+ D D+   + +   F   T  ++ +  +T K +GFGFV  +  D+AA A  S
Sbjct: 91  VLFVGNLSYDTDQ---YSLKDAFPGATAARIAKFQDTQKPRGFGFVEFSTPDDAASAFDS 261

Query: 338 LNGYRLGD-RVLQVSFKTN 355
             G R  D R +++SF ++
Sbjct: 262 --GEREVDGRQVKLSFASS 312
>05273
          Length = 1009

 Score = 35.8 bits (81), Expect = 0.030,   Method: Compositional matrix adjust.
 Identities = 18/51 (35%), Positives = 27/51 (52%), Gaps = 1/51 (1%)
 Frame = -1

Query: 133 PKTMTQKELEQLFSQYGRIITSRILVDQVTGISRGVGFIRF-DKRIEAEEA 182
           P   T   L + F ++G I  + ++ D+ TG SRG GF+   D+R   E A
Sbjct: 175 PIITTDHSLREYFDKFGDIDEAVVITDRQTGKSRGYGFVTMADRRARTEPA 23

 Score = 35.0 bits (79), Expect = 0.053,   Method: Compositional matrix adjust.
 Identities = 15/35 (42%), Positives = 20/35 (57%)
 Frame = -1

Query: 293 LWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTN 327
           L + F  FG +    VI D  T K +G+GFVTM +
Sbjct: 151 LREYFDKFGDIDEAVVITDRQTGKSRGYGFVTMAD 47
>25746
          Length = 475

 Score = 35.4 bits (80), Expect = 0.034,   Method: Compositional matrix adjust.
 Identities = 24/90 (26%), Positives = 43/90 (47%), Gaps = 7/90 (7%)
 Frame = +1

Query: 113 SYARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITS-------RILVDQVTGIS 165
           SY+     + +  ++YVSGLP  +T ++ ++L S+YG I+           L     G  
Sbjct: 37  SYSWFDMDTEKSTHVYVSGLPSDLTDEQFQELMSKYGLIMFDPHTHKPKLKLYRNHDGTL 216

Query: 166 RGVGFIRFDKRIEAEEAIKGLNGQKPPGAT 195
           +G G   + K+   + A+  L+G    G+T
Sbjct: 217 KGDGLCCYIKQESVDLALNILDGSDVHGST 306
>29364
          Length = 1126

 Score = 35.4 bits (80), Expect = 0.039,   Method: Compositional matrix adjust.
 Identities = 24/76 (31%), Positives = 42/76 (55%)
 Frame = +1

Query: 136 MTQKELEQLFSQYGRIITSRILVDQVTGISRGVGFIRFDKRIEAEEAIKGLNGQKPPGAT 195
           + +++LE+ F  YGR  T  IL      I  G GF+ F+   +A++A+  LNG++  G  
Sbjct: 1   VRERDLERFFKGYGR--TRDIL------IKNGYGFVEFEDYRDADDAVYELNGKELLG-- 150

Query: 196 EPITVKFANNPSQKTN 211
           E + V+ A   ++ +N
Sbjct: 151 ERVVVEPARGTARGSN 198

 Score = 33.1 bits (74), Expect = 0.16,   Method: Compositional matrix adjust.
 Identities = 16/39 (41%), Positives = 24/39 (61%)
 Frame = +1

Query: 81  GYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYARPSS 119
           GYGFV + D +DA+ A+  LNG  L  + + V  AR ++
Sbjct: 70  GYGFVEFEDYRDADDAVYELNGKELLGERVVVEPARGTA 186

 Score = 29.3 bits (64), Expect = 2.6,   Method: Compositional matrix adjust.
 Identities = 18/60 (30%), Positives = 29/60 (48%), Gaps = 1/60 (1%)
 Frame = +1

Query: 290 ESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYR-LGDRVL 348
           E  L + F  +G   ++ +          G+GFV   +Y +A  A+  LNG   LG+RV+
Sbjct: 7   ERDLERFFKGYGRTRDILI--------KNGYGFVEFEDYRDADDAVYELNGKELLGERVV 162
>20169
          Length = 1364

 Score = 35.0 bits (79), Expect = 0.053,   Method: Compositional matrix adjust.
 Identities = 19/67 (28%), Positives = 33/67 (49%)
 Frame = -1

Query: 124  DANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGISRGVGFIRFDKRIEAEEAI 183
            D  +YV  L     ++ELE  F++YG +         V     G  F+ F+   +AE+A+
Sbjct: 1073 DCKVYVGELGHGCAKQELEDKFAKYGPLKNV-----WVARRPAGFAFVEFEDNRDAEDAV 909

Query: 184  KGLNGQK 190
            + L+G +
Sbjct: 908  QALDGAR 888
>02809
          Length = 1475

 Score = 34.7 bits (78), Expect = 0.061,   Method: Compositional matrix adjust.
 Identities = 19/65 (29%), Positives = 32/65 (49%)
 Frame = -1

Query: 124  DANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGISRGVGFIRFDKRIEAEEAI 183
            D  +YV  L     ++ELE  F++YG +         V     G  F+ F+   +AE+A+
Sbjct: 1337 DCKVYVGELGHGCAKQELEDKFAKYGPLKNV-----WVARRPAGFAFVEFEDNRDAEDAV 1173

Query: 184  KGLNG 188
            + L+G
Sbjct: 1172 QALDG 1158
>12096
          Length = 1585

 Score = 34.7 bits (78), Expect = 0.065,   Method: Compositional matrix adjust.
 Identities = 19/65 (29%), Positives = 32/65 (49%)
 Frame = -3

Query: 125  ANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGISRGVGFIRFDKRIEAEEAIK 184
            A + + GL  T+ + ++ Q   + G        + +VTG SRG GF+ F  + EA+  + 
Sbjct: 1223 ATILLRGLSNTLVENDIIQELIRIGMPPKDVRFMRRVTGASRGFGFVEFQSQSEAQRWMD 1044

Query: 185  GLNGQ 189
               GQ
Sbjct: 1043 HNQGQ 1029
>03856
          Length = 1292

 Score = 34.3 bits (77), Expect = 0.071,   Method: Compositional matrix adjust.
 Identities = 19/68 (27%), Positives = 34/68 (50%)
 Frame = +1

Query: 49   NMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTK 108
             + ++EL  LF    EI     ++D +    +GY F  +  P+  + A N   G R+Q+ 
Sbjct: 970  ELKEQELYKLFPKAQEITVPVRMKDNL---PIGYAFATFATPEQCKDAHNKGQGARVQSY 1140

Query: 109  TIKVSYAR 116
            ++ V YA+
Sbjct: 1141 SLVVLYAK 1164
>22492
          Length = 785

 Score = 34.3 bits (77), Expect = 0.090,   Method: Compositional matrix adjust.
 Identities = 12/32 (37%), Positives = 20/32 (62%)
 Frame = +1

Query: 87  YIDPKDAEKAINTLNGLRLQTKTIKVSYARPS 118
           ++DP+DAE A+  LNG R     + + +AR +
Sbjct: 352 FVDPRDAEDALYYLNGTRFXRTELDIEFARET 447
>23250
          Length = 1617

 Score = 33.5 bits (75), Expect = 0.12,   Method: Compositional matrix adjust.
 Identities = 14/47 (29%), Positives = 27/47 (57%)
 Frame = -1

Query: 127  LYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGISRGVGFIRF 173
            +Y+  +P    + ++++ FSQ+GR+   R+     TG S+G  F+ F
Sbjct: 1329 VYLGHIPAGFYEPQMKRFFSQFGRVTRLRLSRSTKTGGSKGYAFLEF 1189
>28605
          Length = 697

 Score = 33.5 bits (75), Expect = 0.13,   Method: Compositional matrix adjust.
 Identities = 14/52 (26%), Positives = 30/52 (57%)
 Frame = -3

Query: 137 TQKELEQLFSQYGRIITSRILVDQVTGISRGVGFIRFDKRIEAEEAIKGLNG 188
           ++ EL++LFS+YG ++ + +  ++        GF++F    E   A++ +NG
Sbjct: 530 SEAELQELFSKYGNVLDTLVHHNR-------YGFVQFSTEEEGRRAVEAMNG 396

 Score = 32.0 bits (71), Expect = 0.38,   Method: Compositional matrix adjust.
 Identities = 20/64 (31%), Positives = 35/64 (54%), Gaps = 1/64 (1%)
 Frame = -3

Query: 279 IFVYNLAPD-ADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIAS 337
           +FV NL+ D   E+ L ++F  +G V +  V    + N+   +GFV  +  +E   A+ +
Sbjct: 563 VFVANLSSDETSEAELQELFSKYGNVLDTLV----HHNR---YGFVQFSTEEEGRRAVEA 405

Query: 338 LNGY 341
           +NGY
Sbjct: 404 MNGY 393

 Score = 29.6 bits (65), Expect = 1.8,   Method: Compositional matrix adjust.
 Identities = 16/75 (21%), Positives = 32/75 (42%)
 Frame = -3

Query: 41  LIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTL 100
            + N      ++ EL+ LF   G +    +  ++       YGFV +   ++  +A+  +
Sbjct: 560 FVANLSSDETSEAELQELFSKYGNVLDTLVHHNR-------YGFVQFSTEEEGRRAVEAM 402

Query: 101 NGLRLQTKTIKVSYA 115
           NG     K +K + A
Sbjct: 401 NGYMFYRKKLKCNXA 357
>11126
          Length = 1061

 Score = 31.6 bits (70), Expect = 0.49,   Method: Compositional matrix adjust.
 Identities = 25/111 (22%), Positives = 42/111 (37%)
 Frame = -3

Query: 16  NGPTTVNNNCSSPVDSGNTEDSKTNLIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKI 75
           + PT+       P      E    ++ V  +    T EEL+  F   G +    ++ DK 
Sbjct: 699 SSPTSAATASPFPSQEDKIEADLRSVYVGNVDYGATAEELEQHFHGCGSVNRVTILCDKY 520

Query: 76  TGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYARPSSASIRDAN 126
           +G   G+ +V + D      A  T      + + IKV+  R +   I   N
Sbjct: 519 SGHPKGFAYVEFADKDSVVTAKCTGMDSLFRGRQIKVTPKRTNRPGISTTN 367
>33504
          Length = 282

 Score = 30.8 bits (68), Expect = 0.81,   Method: Composition-based stats.
 Identities = 12/36 (33%), Positives = 24/36 (66%)
 Frame = +1

Query: 125 ANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQ 160
           A +++ GLP  +T+ ++  +FSQYG I+   ++ D+
Sbjct: 169 AWVFIGGLPYDLTEGDIICVFSQYGEIVNINLVRDK 276

 Score = 28.5 bits (62), Expect = 4.7,   Method: Composition-based stats.
 Identities = 12/29 (41%), Positives = 19/29 (65%)
 Frame = +1

Query: 46  LPQNMTQEELKSLFGSIGEIESCKLVRDK 74
           LP ++T+ ++  +F   GEI +  LVRDK
Sbjct: 190 LPYDLTEGDIICVFSQYGEIVNINLVRDK 276
>19570
          Length = 1472

 Score = 30.8 bits (68), Expect = 0.81,   Method: Compositional matrix adjust.
 Identities = 22/84 (26%), Positives = 39/84 (46%)
 Frame = -1

Query: 1   METQLSNGPTCNNTANGPTTVNNNCSSPVDSGNTEDSKTNLIVNYLPQNMTQEELKSLFG 60
           M T++ + P  ++       +    +SPV+    +  KT +    L ++ T   LKSL  
Sbjct: 782 MRTEVEHPPAMSSRCVA-NELKRIVTSPVEEPRCKCVKTQISRELLLRDHTLI*LKSLIY 606

Query: 61  SIGEIESCKLVRDKITGQSLGYGF 84
              +++SC    D I+G+   YGF
Sbjct: 605 PQFQVDSCPPFCDIISGKITPYGF 534
>28372
          Length = 398

 Score = 30.0 bits (66), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 11/32 (34%), Positives = 21/32 (65%)
 Frame = -2

Query: 81  GYGFVNYIDPKDAEKAINTLNGLRLQTKTIKV 112
           G+GFV +    +AE+A + +NG  ++ + I+V
Sbjct: 256 GFGFVTFAHSAEAERARDKMNGTVVEGRKIEV 161
>35180
          Length = 2181

 Score = 29.6 bits (65), Expect = 2.2,   Method: Compositional matrix adjust.
 Identities = 16/66 (24%), Positives = 31/66 (46%)
 Frame = -2

Query: 115 ARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGISRGVGFIRFD 174
            +     I   ++YV G P+ +T   L + F Q+G+I T  +  ++     +G  F+ F 
Sbjct: 290 TKERKDDINSRSVYVKGFPEDITLDTLMEFFEQHGKIDTILMRRNRPDKNFKGSVFVTFS 111

Query: 175 KRIEAE 180
            + E +
Sbjct: 110 NKEEED 93
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|165377065|ref|NP_079923.3| UMP-CMP kinase [Mus
musculus]
         (227 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

01182                                                                 236   4e-63
06512                                                                 113   6e-26
16252                                                                  76   1e-14
30736                                                                  28   2.2  
05422                                                                  28   2.8  
11664                                                                  28   3.1  
22143                                                                  27   9.1  
>01182
          Length = 2762

 Score =  236 bits (603), Expect = 4e-63,   Method: Compositional matrix adjust.
 Identities = 113/189 (59%), Positives = 150/189 (79%)
 Frame = -3

Query: 36   VVFVLGGPGAGKGTQCARIVEKYGYTHLSAGELLRDERKNPDSQYGELIEKYIKEGKIVP 95
            VVFVLGGPGAGKGTQC +I E +GY HLSAG+LLR ER   +S++ + IE +IK G IVP
Sbjct: 2292 VVFVLGGPGAGKGTQCTKIEETFGYKHLSAGDLLRAERAKEESKFKDEIETHIKNGSIVP 2113

Query: 96   VEITISLLKREMDQTMAANAQKNKFLIDGFPRNQDNLQGWNKTMDGKADVSFVLFFDCNN 155
            VEIT SLLK+ M++     ++K+KFLIDGFPRN++NL GWNK MD  A V  VLFF+C  
Sbjct: 2112 VEITCSLLKQAMEE-----SRKDKFLIDGFPRNKNNLDGWNKVMDSVAVVRKVLFFNCPE 1948

Query: 156  EICIERCLERGKSSGRSDDNRESLEKRIQTYLESTKPIIDLYEEMGKVKKIDASKSVDEV 215
            ++CI+RCL+RGK+SGR+DDNRESLEKRI+TY EST PII+ Y++   V +I+A+++ ++V
Sbjct: 1947 DVCIDRCLDRGKNSGRADDNRESLEKRIKTYTESTMPIIEHYKKQSLVAEINANQTEEQV 1768

Query: 216  FGEVVKIFD 224
            F +V K+F+
Sbjct: 1767 FNDVTKVFN 1741
>06512
          Length = 2288

 Score =  113 bits (282), Expect = 6e-26,   Method: Compositional matrix adjust.
 Identities = 57/193 (29%), Positives = 114/193 (59%), Gaps = 4/193 (2%)
 Frame = +1

Query: 36   VVFVLGGPGAGKGTQCARIVEKY-GYTHLSAGELLRDE---RKNPDSQYGELIEKYIKEG 91
            ++F  GGP +GKGTQC R++ +Y    HLS G+++R +   + + D ++ +++   +++G
Sbjct: 1120 IIFFAGGPASGKGTQCKRLLSRYTNAAHLSMGDIIRAQIATQGSADDKW-DMMTDLMRKG 1296

Query: 92   KIVPVEITISLLKREMDQTMAANAQKNKFLIDGFPRNQDNLQGWNKTMDGKADVSFVLFF 151
            ++ P E+T+ LL      ++ +    + +L++G+PRN   L+ +N+ + G+   SF +  
Sbjct: 1297 ELAPEEVTVDLLM----SSLKSQPDAHFYLVEGYPRNLQQLEDFNQKIGGQ---SFTILL 1455

Query: 152  DCNNEICIERCLERGKSSGRSDDNRESLEKRIQTYLESTKPIIDLYEEMGKVKKIDASKS 211
            DC  +I   R   RGK+S R DDN  ++ K++  +  +T PI+  +++ GK+  +   + 
Sbjct: 1456 DCEEDILHYRLTMRGKTSERIDDNLVAIGKKLTYFKNNTLPILKTFDDSGKLVVVGGDRD 1635

Query: 212  VDEVFGEVVKIFD 224
             DE+F ++ K+ D
Sbjct: 1636 EDEIFFDLCKVLD 1674

 Score = 94.7 bits (234), Expect = 3e-20,   Method: Compositional matrix adjust.
 Identities = 55/192 (28%), Positives = 110/192 (57%), Gaps = 3/192 (1%)
 Frame = +1

Query: 36  VVFVLGGPGAGKGTQCARIVEKYG-YTHLSAGELLRDERKNPDSQYG--ELIEKYIKEGK 92
           ++F+ GGPG+GK TQ   +++KY  +  +  G+LLR E  +  S     +++ + + +G+
Sbjct: 331 IIFLTGGPGSGKSTQAELLLQKYPKWVTVPVGDLLRQEINDNGSGNARWKMVSELMSDGE 510

Query: 93  IVPVEITISLLKREMDQTMAANAQKNKFLIDGFPRNQDNLQGWNKTMDGKADVSFVLFFD 152
           +VP ++  +LL   +D+  +A  +   F+I GFPR+ +  + + K + G+ D  F++  D
Sbjct: 511 MVPEDVVDTLL---LDKLKSA-PKAEGFVIQGFPRDMEQAEQYEKLV-GRVDAVFLI--D 669

Query: 153 CNNEICIERCLERGKSSGRSDDNRESLEKRIQTYLESTKPIIDLYEEMGKVKKIDASKSV 212
           C  E   ++ L+R KS+ R D+N  ++ KRI  + ++T P++  +++M K+  ++     
Sbjct: 670 CEEETLSQQLLDRAKSTKRIDNNVNTVAKRIHAFRDNTLPVLKHFDDMEKLFVLNGESPA 849

Query: 213 DEVFGEVVKIFD 224
             V  E+  IF+
Sbjct: 850 KAVAEELAIIFE 885
>16252
          Length = 789

 Score = 76.3 bits (186), Expect = 1e-14,   Method: Compositional matrix adjust.
 Identities = 54/190 (28%), Positives = 95/190 (50%), Gaps = 28/190 (14%)
 Frame = +2

Query: 66  GELLRDERKNPDSQYGELIEKYIKEGKIVPVEITISLLKREMDQTMAANAQKNKFLIDGF 125
           G++LR E  +  S+ G  ++K + EGK+V  ++ ++++   +D+       KN FL+DGF
Sbjct: 2   GDMLRAEISSG-SKLGSELKKVMDEGKLVSDDLVVNMIDSNLDKPEC----KNGFLLDGF 166

Query: 126 PRNQDNLQGWNKTMDG-KADVSFVLFFDCNNEICIERCLER--GKSSG------------ 170
           PR     Q  +  +D  K  +  V+ F  ++ + + R   R   ++SG            
Sbjct: 167 PRTVVQAQKLDSLLDKRKTHLDAVIEFAIDDNLLVRRITGRLIHQASGRSYHEEFAPPKV 346

Query: 171 -------------RSDDNRESLEKRIQTYLESTKPIIDLYEEMGKVKKIDASKSVDEVFG 217
                        RSDDN E+L+KR+++Y + TKP++D Y   G   K+DA+K   +VF 
Sbjct: 347 PMRDDITGELLMKRSDDNAEALKKRLESYHKQTKPLVDYYGLRGLHFKVDAAKQASDVFS 526

Query: 218 EVVKIFDKEG 227
            +  IF ++ 
Sbjct: 527 TIDSIFQRKA 556
>30736
          Length = 520

 Score = 28.5 bits (62), Expect = 2.2,   Method: Compositional matrix adjust.
 Identities = 14/37 (37%), Positives = 20/37 (54%)
 Frame = -2

Query: 34  PLVVFVLGGPGAGKGTQCARIVEKYGYTHLSAGELLR 70
           P  + VLG P +GK T C  +  KYG   L   E+++
Sbjct: 123 PCKLAVLGPPLSGKTTLCHLLANKYGAKVLKVEEIIK 13
>05422
          Length = 1975

 Score = 28.1 bits (61), Expect = 2.8,   Method: Compositional matrix adjust.
 Identities = 14/51 (27%), Positives = 24/51 (47%)
 Frame = +3

Query: 131 NLQGWNKTMDGKADVSFVLFFDCNNEICIERCLERGKSSGRSDDNRESLEK 181
           + QGWN + D     SFVL     N+  ++R  E  K   ++   R  +++
Sbjct: 222 HFQGWNNSWDRLVPESFVLKASEENKTLMKRLTETAKKYRKNRQRRRKIDQ 374
>11664
          Length = 1336

 Score = 28.1 bits (61), Expect = 3.1,   Method: Compositional matrix adjust.
 Identities = 12/34 (35%), Positives = 18/34 (52%)
 Frame = +1

Query: 144 DVSFVLFFDCNNEICIERCLERGKSSGRSDDNRE 177
           DV  +LFF  NN +C+  C+  G ++      RE
Sbjct: 868 DVCVLLFFVHNNNVCLHSCVFXGNAALT*SSGRE 969
>22143
          Length = 370

 Score = 26.6 bits (57), Expect = 9.1,   Method: Compositional matrix adjust.
 Identities = 10/22 (45%), Positives = 15/22 (68%)
 Frame = +3

Query: 85  EKYIKEGKIVPVEITISLLKRE 106
           +KY  +G I+P+E+   LLKR 
Sbjct: 132 DKYFSKGAIIPLELITKLLKRS 197
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|39930335|ref|NP_038882.1| ATP-binding cassette,
sub-family F (GCN20), member 1 [Mus musculus]
         (837 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

03538                                                                 239   4e-63
22801                                                                 157   2e-38
38795                                                                 148   1e-35
33929                                                                  62   9e-10
24147                                                                  56   5e-08
05764                                                                  49   1e-05
02301                                                                  46   7e-05
01623                                                                  45   9e-05
20290                                                                  37   0.033
12308                                                                  37   0.037
30281                                                                  36   0.051
19618                                                                  33   0.43 
01142                                                                  32   0.90 
>03538
          Length = 1974

 Score =  239 bits (609), Expect = 4e-63,   Method: Compositional matrix adjust.
 Identities = 111/179 (62%), Positives = 138/179 (77%)
 Frame = -1

Query: 653  GVGKSXXXXXXXXXXXXXNGEMRKNHRLKIGFFNQQYAEQLHMEETPTEYLQRSFNLPYQ 712
            GVGKS              GE R NHRL++G ++Q  A+QL+++E+P EYL+R F+L YQ
Sbjct: 1971 GVGKSTLLKLLMGDLQPSQGEKRMNHRLRVGKYDQHSADQLNLDESPVEYLKRLFDLQYQ 1792

Query: 713  DARKCLGRFGLESHAHTIQICKLSGGQKARVVFAELACREPDVLILDEPTNNLDIESIDA 772
            DARK LGR GL SHAHTI    LSGGQ+ARV  AEL+CR PDVL+LDEPTNNLDIESIDA
Sbjct: 1791 DARKMLGRVGLASHAHTILNRDLSGGQRARVALAELSCRAPDVLVLDEPTNNLDIESIDA 1612

Query: 773  LGEAINDYKGAVIVVSHDARLITETNCQLWVVEEQGVSQIDGDFDDYKREVLEALGEVM 831
            L +AI ++ G VI+VSHD RLI +TNCQLWVVE+  ++++DGDFDDY+RE+LEALGE +
Sbjct: 1611 LADAIKNFTGGVIIVSHDERLIRDTNCQLWVVEDNTINEVDGDFDDYRRELLEALGETL 1435

 Score = 51.6 bits (122), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 25/66 (37%), Positives = 41/66 (62%)
 Frame = -1

Query: 441  TQKFSGGWRMRVSLARALFMEPTLLMLDEPTNHLDLNAVIWLNNYLQGWRKTLLIVSHDQ 500
             +  SGG R RV+LA      P +L+LDEPTN+LD+ ++  L + ++ +   ++IVSHD+
Sbjct: 1734 NRDLSGGQRARVALAELSCRAPDVLVLDEPTNNLDIESIDALADAIKNFTGGVIIVSHDE 1555

Query: 501  GFLDDV 506
              + D 
Sbjct: 1554 RLIRDT 1537
>22801
          Length = 753

 Score =  157 bits (396), Expect = 2e-38,   Method: Composition-based stats.
 Identities = 72/104 (69%), Positives = 88/104 (84%)
 Frame = -1

Query: 728 HTIQICKLSGGQKARVVFAELACREPDVLILDEPTNNLDIESIDALGEAINDYKGAVIVV 787
           HTI    LSGGQ+ARV  AEL+CR PDVL+LDEPTNNLDIESIDAL +AI ++ G VI+V
Sbjct: 753 HTILNRDLSGGQRARVALAELSCRAPDVLVLDEPTNNLDIESIDALADAIKNFTGGVIIV 574

Query: 788 SHDARLITETNCQLWVVEEQGVSQIDGDFDDYKREVLEALGEVM 831
           SHD RLI +TNCQLWVVE+  ++++DGDFDDY+RE+LEALGE +
Sbjct: 573 SHDERLIRDTNCQLWVVEDNTINEVDGDFDDYRRELLEALGETL 442

 Score = 50.8 bits (120), Expect = 2e-06,   Method: Composition-based stats.
 Identities = 25/64 (39%), Positives = 41/64 (64%)
 Frame = -1

Query: 442 QKFSGGWRMRVSLARALFMEPTLLMLDEPTNHLDLNAVIWLNNYLQGWRKTLLIVSHDQG 501
           +  SGG R RV+LA      P +L+LDEPTN+LD+ ++  L + ++ +   ++IVSHD+ 
Sbjct: 738 RDLSGGQRARVALAELSCRAPDVLVLDEPTNNLDIESIDALADAIKNFTGGVIIVSHDER 559

Query: 502 FLDD 505
            + D
Sbjct: 558 LIRD 547
>38795
          Length = 792

 Score =  148 bits (373), Expect = 1e-35,   Method: Compositional matrix adjust.
 Identities = 97/265 (36%), Positives = 137/265 (51%), Gaps = 7/265 (2%)
 Frame = +1

Query: 400 AAEKLEKVYEELXXXXXXXXXXXXXXXXXGLGFDPEMQNRPTQKFSGGWRMRVSLARALF 459
           + ++L  VY+ L                 GLGF  +MQ+   + FSGGWRMR+ LARAL+
Sbjct: 1   SHDRLLAVYDRLDELDSTKALAKAGFILHGLGFSKDMQHTKVKNFSGGWRMRIGLARALY 180

Query: 460 MEPTLLMLDEPTNHLDLNAVIWLNNYLQGWRKTLLIVSHDQGFLDDVCTDIIHLDTQRLH 519
           + P+LL+LDEPTNHLDLNA +WL   L+ + + L+I+SH Q FL+ VC  IIH++ ++L 
Sbjct: 181 LRPSLLLLDEPTNHLDLNACVWLEEELKNYPRILVIISHSQDFLNGVCNSIIHMNQKKLQ 360

Query: 520 YYRGNYMTFXXXXXXXXXXXXXXXX-----XXXXXXXXXXAGGKSTKQA-EKQTKEVLTR 573
           YY GNY ++                                G  S K A + Q+KE    
Sbjct: 361 YYGGNYDSYVQTRLELLENQAKRYKWEQDQISHMKNYIARFGHGSAKLARQAQSKE---- 528

Query: 574 KQQKCRRKNQDEESQEPPELLKRPKEYTVRFTFXXXXXXXXXVLGLHGVTFGYEGQKP-L 632
              K  +K  D    E     K   + T+ F F         V+ +  V+F Y   KP +
Sbjct: 529 ---KTLKKMVDGGLTE-----KVTSDKTLSFYFPSCGTIPPPVIMVQHVSFRYNETKPYI 684

Query: 633 FKNLDFGIDMDSRICIVGPNGVGKS 657
           ++NLDFGID+D+R+ +VGPNG GKS
Sbjct: 685 YQNLDFGIDLDTRVALVGPNGAGKS 759

 Score = 46.6 bits (109), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 33/123 (26%), Positives = 59/123 (47%), Gaps = 8/123 (6%)
 Frame = +1

Query: 713 DARKCLGRFGLESHA--------HTIQICKLSGGQKARVVFAELACREPDVLILDEPTNN 764
           D+ K L + G   H         HT ++   SGG + R+  A      P +L+LDEPTN+
Sbjct: 46  DSTKALAKAGFILHGLGFSKDMQHT-KVKNFSGGWRMRIGLARALYLRPSLLLLDEPTNH 222

Query: 765 LDIESIDALGEAINDYKGAVIVVSHDARLITETNCQLWVVEEQGVSQIDGDFDDYKREVL 824
           LD+ +   L E + +Y   ++++SH    +      +  + ++ +    G++D Y +  L
Sbjct: 223 LDLNACVWLEEELKNYPRILVIISHSQDFLNGVCNSIIHMNQKKLQYYGGNYDSYVQTRL 402

Query: 825 EAL 827
           E L
Sbjct: 403 ELL 411

 Score = 34.3 bits (77), Expect = 0.19,   Method: Compositional matrix adjust.
 Identities = 17/33 (51%), Positives = 21/33 (63%)
 Frame = +1

Query: 310 LFVNADLYIVAGRRYGLVGPNGKGKTTLLKHIA 342
           ++ N D  I    R  LVGPNG GK+TLLK I+
Sbjct: 682 IYQNLDFGIDLDTRVALVGPNGAGKSTLLKLIS 780
>33929
          Length = 408

 Score = 62.0 bits (149), Expect = 9e-10,   Method: Composition-based stats.
 Identities = 30/83 (36%), Positives = 50/83 (60%)
 Frame = +1

Query: 273 ENDFSVSQAEVSSRQAMLENASDIKLEKFSISAHGKELFVNADLYIVAGRRYGLVGPNGK 332
           E D +     V+   A   ++ D+ +   SI  HG EL +++ L +  G+RYGL+G NG 
Sbjct: 133 EMDIAAQHRSVTGVLASHGDSRDLHIHNMSILFHGAELLMDSKLEMNVGKRYGLIGLNGC 312

Query: 333 GKTTLLKHIANRALSIPPNIDVL 355
           GK++LL  +AN+ ++IP +ID+ 
Sbjct: 313 GKSSLLAALANKEVAIPDHIDIF 381
>24147
          Length = 394

 Score = 56.2 bits (134), Expect = 5e-08,   Method: Compositional matrix adjust.
 Identities = 26/59 (44%), Positives = 37/59 (62%)
 Frame = +2

Query: 653 GVGKSXXXXXXXXXXXXXNGEMRKNHRLKIGFFNQQYAEQLHMEETPTEYLQRSFNLPY 711
           GVGKS              GE R NHRL++G ++Q  A+QL+++E+P EYL+R F+L Y
Sbjct: 2   GVGKSTLLKLLMGDLQPSQGEKRMNHRLRVGKYDQHSADQLNLDESPVEYLKRLFDLQY 178
>05764
          Length = 1395

 Score = 48.5 bits (114), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 25/70 (35%), Positives = 42/70 (60%), Gaps = 2/70 (2%)
 Frame = -2

Query: 431 GFDPEMQNRPTQKFSGGWRMRVSLARALFMEPTLLMLDEPTNHLDLNAVIWLNNYLQGWR 490
           G+D ++  + TQ  SGG + RV++ARAL   P +L+LDE T+ LD  +   +   L   R
Sbjct: 749 GYDTQVGGKGTQ-LSGGQKQRVAIARALVRNPIILLLDEATSALDTESEKLVQAALDNAR 573

Query: 491 --KTLLIVSH 498
             +T ++++H
Sbjct: 572 EGRTCIVIAH 543

 Score = 47.8 bits (112), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 31/77 (40%), Positives = 43/77 (55%), Gaps = 2/77 (2%)
 Frame = -2

Query: 734 KLSGGQKARVVFAELACREPDVLILDEPTNNLDIESIDALGEAINDYKGA--VIVVSHDA 791
           +LSGGQK RV  A    R P +L+LDE T+ LD ES   +  A+++ +     IV++H  
Sbjct: 716 QLSGGQKQRVAIARALVRNPIILLLDEATSALDTESEKLVQAALDNAREGRTCIVIAH-- 543

Query: 792 RLITETNCQLWVVEEQG 808
           RL T  N  +  V E G
Sbjct: 542 RLSTIQNADVIFVMENG 492
>02301
          Length = 1098

 Score = 45.8 bits (107), Expect = 7e-05,   Method: Compositional matrix adjust.
 Identities = 27/63 (42%), Positives = 40/63 (63%), Gaps = 2/63 (3%)
 Frame = -2

Query: 735 LSGGQKARVVFAELACREPDVLILDEPTNNLDIESIDALGEAIND-YKG-AVIVVSHDAR 792
           LSGGQK R+  A    R+P +L+LDE T+ LD +S   +  AIN+  +G  V++++H  R
Sbjct: 686 LSGGQKQRLAIARALVRQPAILLLDEATSALDTQSESLVQSAINECTRGRTVVIIAH--R 513

Query: 793 LIT 795
           L T
Sbjct: 512 LTT 504

 Score = 41.6 bits (96), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 22/70 (31%), Positives = 41/70 (58%), Gaps = 2/70 (2%)
 Frame = -2

Query: 431 GFDPEMQNRPTQKFSGGWRMRVSLARALFMEPTLLMLDEPTNHLDLNAVIWLNNYLQGWR 490
           G+D  +  R     SGG + R+++ARAL  +P +L+LDE T+ LD  +   + + +    
Sbjct: 722 GYDTSVGERGLL-LSGGQKQRLAIARALVRQPAILLLDEATSALDTQSESLVQSAINECT 546

Query: 491 --KTLLIVSH 498
             +T++I++H
Sbjct: 545 RGRTVVIIAH 516
>01623
          Length = 1414

 Score = 45.4 bits (106), Expect = 9e-05,   Method: Compositional matrix adjust.
 Identities = 28/84 (33%), Positives = 41/84 (48%)
 Frame = +3

Query: 735 LSGGQKARVVFAELACREPDVLILDEPTNNLDIESIDALGEAINDYKGAVIVVSHDARLI 794
           LSGGQ+ R+  A    + P++L+LDE T+ LD ES   + +A+    G   V++   RL 
Sbjct: 453 LSGGQRQRIAIARAILKNPEILLLDEATSALDAESEYLVQDALEKLMGGRTVITIAHRLS 632

Query: 795 TETNCQLWVVEEQGVSQIDGDFDD 818
           T        V   GV    G + D
Sbjct: 633 TIKTANQIAVLTDGVVAEMGSYQD 704

 Score = 42.0 bits (97), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 23/71 (32%), Positives = 40/71 (56%), Gaps = 2/71 (2%)
 Frame = +3

Query: 430 LGFDPEMQNRPTQKFSGGWRMRVSLARALFMEPTLLMLDEPTNHLDLNAVIWLNNYLQGW 489
           LG D  +  R     SGG R R+++ARA+   P +L+LDE T+ LD  +   + + L+  
Sbjct: 414 LGLDTMVGER-GMMLSGGQRQRIAIARAILKNPEILLLDEATSALDAESEYLVQDALEKL 590

Query: 490 R--KTLLIVSH 498
              +T++ ++H
Sbjct: 591 MGGRTVITIAH 623
>20290
          Length = 1550

 Score = 37.0 bits (84), Expect = 0.033,   Method: Compositional matrix adjust.
 Identities = 22/69 (31%), Positives = 35/69 (50%), Gaps = 4/69 (5%)
 Frame = +3

Query: 435  EMQNRPTQKFSGGWRMRVSLARALFMEPTLLMLDEPTNHLD----LNAVIWLNNYLQGWR 490
            E+ ++  Q  SGG   RV+L   L     + ++DEP+ +LD    L A   +  Y+   +
Sbjct: 1020 EIMDQEVQNLSGGELQRVALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRYILHAK 1199

Query: 491  KTLLIVSHD 499
            KT  +V HD
Sbjct: 1200 KTGFVVEHD 1226

 Score = 35.4 bits (80), Expect = 0.083,   Method: Compositional matrix adjust.
 Identities = 25/81 (30%), Positives = 37/81 (45%), Gaps = 4/81 (4%)
 Frame = +3

Query: 731  QICKLSGGQKARVVFAELACREPDVLILDEPTNNLDIESIDALGEAINDY----KGAVIV 786
            ++  LSGG+  RV       +  DV ++DEP+  LD E      + I  Y    K    V
Sbjct: 1035 EVQNLSGGELQRVALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRYILHAKKTGFV 1214

Query: 787  VSHDARLITETNCQLWVVEEQ 807
            V HD  + T    ++ V+E Q
Sbjct: 1215 VEHDFIMATYLADRVIVIEGQ 1277
>12308
          Length = 698

 Score = 37.0 bits (84), Expect = 0.037,   Method: Compositional matrix adjust.
 Identities = 36/152 (23%), Positives = 62/152 (40%), Gaps = 15/152 (9%)
 Frame = -3

Query: 632 LFKNLDFGIDMDSRICIVGPNGVGKSXXXXXXXXXXXXXNGEMRKNHRLKIGFFNQQ--- 688
           L   L F +     + + GPNG GKS              G + K  + K+ +  Q+   
Sbjct: 492 LIPELSFEVKAGMNVLVCGPNGCGKSSLFRILGELWPLFGGSLTKPEKGKLFYIPQRPYM 313

Query: 689 ----YAEQLHMEETPTEYLQRSFNLPYQDARKCLGRFGL------ESHAHTIQ--ICKLS 736
                 +Q+   ++  E L++      ++    LG+  L      E     +Q  +  LS
Sbjct: 312 TVGTLRDQVTYPDSHEEQLRKGTR--DEELADILGKVQLDYVLQREGGWDAVQDWMDVLS 139

Query: 737 GGQKARVVFAELACREPDVLILDEPTNNLDIE 768
           GG+K R+  A L   +P   ILDE T+ + ++
Sbjct: 138 GGEKQRIAMARLFYHKPQFAILDECTSAVSVD 43

 Score = 30.4 bits (67), Expect = 3.2,   Method: Compositional matrix adjust.
 Identities = 12/42 (28%), Positives = 25/42 (59%)
 Frame = -3

Query: 444 FSGGWRMRVSLARALFMEPTLLMLDEPTNHLDLNAVIWLNNY 485
            SGG + R+++AR  + +P   +LDE T+ + ++   ++  Y
Sbjct: 144 LSGGEKQRIAMARLFYHKPQFAILDECTSAVSVDVEGFMYQY 19
>30281
          Length = 821

 Score = 36.2 bits (82), Expect = 0.051,   Method: Compositional matrix adjust.
 Identities = 27/89 (30%), Positives = 48/89 (53%), Gaps = 7/89 (7%)
 Frame = -2

Query: 444 FSGGWRMRVSLARALFMEPTLLMLDEPTNHLD-------LNAVIWLNNYLQGWRKTLLIV 496
            SGG + RVS+ARA++ +  + +LD+P + +D        + VI  N  L+G   T ++V
Sbjct: 634 LSGGQKQRVSVARAVYSDSDVYLLDDPLSAVDSHVGKAIFSKVIGPNGLLRG--TTRVLV 461

Query: 497 SHDQGFLDDVCTDIIHLDTQRLHYYRGNY 525
           +H   +L  V   ++ +D +     RG+Y
Sbjct: 460 THGVHWLPMVDEILVLMDGKISE--RGSY 380

 Score = 32.3 bits (72), Expect = 0.79,   Method: Compositional matrix adjust.
 Identities = 15/34 (44%), Positives = 20/34 (58%)
 Frame = -2

Query: 733 CKLSGGQKARVVFAELACREPDVLILDEPTNNLD 766
             LSGGQK RV  A     + DV +LD+P + +D
Sbjct: 640 INLSGGQKQRVSVARAVYSDSDVYLLDDPLSAVD 539
>19618
          Length = 974

 Score = 33.1 bits (74), Expect = 0.43,   Method: Compositional matrix adjust.
 Identities = 19/67 (28%), Positives = 30/67 (44%)
 Frame = +2

Query: 735 LSGGQKARVVFAELACREPDVLILDEPTNNLDIESIDALGEAINDYKGAVIVVSHDARLI 794
           LSGG+K R+  A L   +P   ILDE T+ + ++    +     +    +  VSH   L 
Sbjct: 197 LSGGEKQRIAMARLFYHKPQFAILDECTSAVSVDVEGKMYSYCREVGITLFTVSHRKSLW 376

Query: 795 TETNCQL 801
              +  L
Sbjct: 377 VHHDYYL 397

 Score = 32.7 bits (73), Expect = 0.68,   Method: Compositional matrix adjust.
 Identities = 17/55 (30%), Positives = 31/55 (56%)
 Frame = +2

Query: 444 FSGGWRMRVSLARALFMEPTLLMLDEPTNHLDLNAVIWLNNYLQGWRKTLLIVSH 498
            SGG + R+++AR  + +P   +LDE T+ + ++    + +Y +    TL  VSH
Sbjct: 197 LSGGEKQRIAMARLFYHKPQFAILDECTSAVSVDVEGKMYSYCREVGITLFTVSH 361
>01142
          Length = 729

 Score = 32.3 bits (72), Expect = 0.90,   Method: Composition-based stats.
 Identities = 30/80 (37%), Positives = 42/80 (52%), Gaps = 5/80 (6%)
 Frame = -1

Query: 735 LSGGQKARVVFAELACREPDVLILDEPTNNLDIESIDALGEAINDYKGA-----VIVVSH 789
           LS GQ+  V  A    R   VLILDE T  +D+E+ DAL +  N  + A     V+ ++H
Sbjct: 486 LSVGQRQLVCLARTLLRRSRVLILDEATAAVDMET-DALIQ--NTLRSAFSVCTVLTIAH 316

Query: 790 DARLITETNCQLWVVEEQGV 809
             RL T  +    +V E+GV
Sbjct: 315 --RLHTILDYDKIMVLEEGV 262
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|21312250|ref|NP_082560.1| Bardet-Biedl syndrome 5
[Mus musculus]
         (341 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

18333                                                                 237   5e-63
17934                                                                 160   1e-39
05428                                                                  27   9.0  
>18333
          Length = 411

 Score =  237 bits (604), Expect = 5e-63,   Method: Compositional matrix adjust.
 Identities = 108/135 (80%), Positives = 123/135 (91%)
 Frame = -1

Query: 30  LIDCLDSIEDTKGNNGDRGRLLVTNLRIIWHSLALPRVNLSIGYNCILNITTRTANSKLR 89
           LID LD++EDTKGNNGDRGRL+VTNLRIIWHSLA+PR NLSIG+NC++NI+TRTA S LR
Sbjct: 405 LIDRLDAVEDTKGNNGDRGRLIVTNLRIIWHSLAIPRANLSIGFNCVINISTRTAQSNLR 226

Query: 90  GQTEALYILTKCNTTRFEFIFTNLVPGSPRLFTSVIAVHRAYETSKMYRDFKLRSAVIQN 149
           G  EALY+L KCN TRFEFIFTNL+PGSPRLFTSVI+V RAYETSK+YRD KLR A++QN
Sbjct: 225 GTVEALYVLCKCNNTRFEFIFTNLIPGSPRLFTSVISVLRAYETSKLYRDLKLRGALVQN 46

Query: 150 KQLRLLPQEHVYDKI 164
           KQLRLLPQE VYDK+
Sbjct: 45  KQLRLLPQEQVYDKV 1

 Score = 36.6 bits (83), Expect = 0.016,   Method: Compositional matrix adjust.
 Identities = 17/63 (26%), Positives = 35/63 (55%)
 Frame = -1

Query: 162 DKINGVWNLSSDQGNLGTFFITNVRIVWHANMNDSFNVSIPYLQIRSIKIRDSKFGLALV 221
           D+++ V +   + G+ G   +TN+RI+WH+      N+SI +  + +I  R ++  L   
Sbjct: 399 DRLDAVEDTKGNNGDRGRLIVTNLRIIWHSLAIPRANLSIGFNCVINISTRTAQSNLRGT 220

Query: 222 IES 224
           +E+
Sbjct: 219 VEA 211
>17934
          Length = 1008

 Score =  160 bits (404), Expect = 1e-39,   Method: Compositional matrix adjust.
 Identities = 73/113 (64%), Positives = 89/113 (78%)
 Frame = +1

Query: 229 GGYVLGFKIDPVEKLQESVKEINSLHKVYSASPIFGVNYEMEEKPQPLEALTVEQIQDDV 288
           G        DP  KLQ+  KEI +LH++YS  PIFGV +E E+KPQ +E LT E +QDDV
Sbjct: 64  GAMCWDSAFDPPGKLQQVAKEIQNLHRIYSTCPIFGVEFETEDKPQSMEELTTEAVQDDV 243

Query: 289 EIDSDDHTDAFVAYFADGNKQQDREPVFSEELGLAIEKLKDGFTLQGLWEVMS 341
           EI++D HTDAF AYFADGNK++DREPVFSEELGLA+EKLKDGFT+ GLWEV++
Sbjct: 244 EIENDPHTDAFAAYFADGNKEKDREPVFSEELGLAVEKLKDGFTIAGLWEVLA 402

 Score = 40.4 bits (93), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 17/25 (68%), Positives = 21/25 (84%)
 Frame = +3

Query: 215 KFGLALVIESSQQSGGYVLGFKIDP 239
            FG+ALV+E+S  SGGYVLGF+I P
Sbjct: 21  SFGVALVVETSVMSGGYVLGFRIRP 95
>05428
          Length = 782

 Score = 27.3 bits (59), Expect = 9.0,   Method: Compositional matrix adjust.
 Identities = 11/38 (28%), Positives = 23/38 (60%)
 Frame = +1

Query: 222 IESSQQSGGYVLGFKIDPVEKLQESVKEINSLHKVYSA 259
           ++ S Q+ G    +K+  ++K+  + K+  +LHKVY+ 
Sbjct: 595 VKESLQT*GICTSYKLSKLQKILFTYKQTKTLHKVYTV 708
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|62241019|ref|NP_796214.2| hypothetical protein
LOC320714 [Mus musculus]
         (1133 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

33460                                                                 218   5e-63
>33460
          Length = 1303

 Score =  218 bits (554), Expect(2) = 5e-63,   Method: Compositional matrix adjust.
 Identities = 135/387 (34%), Positives = 203/387 (52%), Gaps = 7/387 (1%)
 Frame = +2

Query: 609 VFLKADCPHPIRFSKLCVSFNNQVYNQFCVLEE---ASKASEVLENLTQGKMCLVPGKTR 665
           V  +  CP P+RFSKL +  +N  Y   C L +    + AS   E      + L PGK R
Sbjct: 2   VCFRISCPLPMRFSKLSLQMSNTRYQASCELLDVRGTNAASASREEKEGHDLYLEPGKPR 181

Query: 666 KLSFKFVAKTEDVGKKIEITSVDLFLGSESGRCVVLSWQGGGGDAASSQEALQAARSFKR 725
              F F+   EDVG +IE+TSV L +G+E+G C VL W GGGGD   S      A     
Sbjct: 182 LYHFSFLPAKEDVGAQIEMTSVSLEMGTETGCCAVLRWLGGGGD---SINGTAPAPYLLT 352

Query: 726 RPKLAEDE-IHWDSVIIQASTMIISRVPNISVHLRHEPPALMNEMYCLVVTVQSHEKSPI 784
           +P  A  +   W    +     +  R   + + + H+ P L+NE YC+ VTV + E S +
Sbjct: 353 KPSAASSQAFDWALFKVNPLIRVTPRQALLELSVDHQSPCLINEFYCITVTVTNMEHSHV 532

Query: 785 RDVKLTAGLKPGQDANLTQKTHVTLHGAELCD--ESYPALLTDIPVGDLHPGEQLEKTVY 842
            D KL+ GL+  Q++     TH+    ++  D  E+  +LL    +G L  GEQ+ +  +
Sbjct: 533 HDAKLSLGLQKDQES-FDTTTHICSDSSQDGDMAEAKSSLLD---LGTLKTGEQVSRQFF 700

Query: 843 VRCGTVGSRMFLVYVSYLINTTVEGKEIICKCHKDDTVTIETVFPFDVAVRFVSTKFEHL 902
           V+C   G+R   V V Y +  +     + C C K++++T+  V PF+V++   S KFE +
Sbjct: 701 VKCLQSGTRSLAVKVEYGVEVSQGQHTVTCHCQKEESITLPAVPPFEVSLLLHSLKFEAI 880

Query: 903 ERVYADIPFLLMTDVLSASPWALTIVSSELQLAPSM-TAMDHLESQIDKVVLQTGESASE 961
           E V+A+ PFLLM D+   SPW + I +S + L+  + TA D  +SQI++V L+  E  SE
Sbjct: 881 EAVHAEEPFLLMADIRCTSPWPVEIKTSSINLSQYIRTASDEFQSQIEEVELKKSECGSE 1060

Query: 962 CFCLRCPSAGNIEGGVATGHYIISWKR 988
           C  L   +A +I+  V  G Y I W+R
Sbjct: 1061CLWLV--AASSIQPSVEMGTYSIHWRR 1135

 Score = 43.5 bits (101), Expect(2) = 5e-63,   Method: Composition-based stats.
 Identities = 18/45 (40%), Positives = 32/45 (71%)
 Frame = +3

Query: 1002 ITLPHVIAENIPLHVNADLPSFGRVRESLPVRYHLQNKTDLVQDV 1046
            + LP V  E+IP+ ++  LP++GRV+  LP+ Y L+N+T  +Q++
Sbjct: 1167 LPLPTVNIEHIPISMHLQLPAYGRVKTLLPLTYLLRNRTAYIQEL 1301
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6755226|ref|NP_035330.1| protein tyrosine phosphatase
4a1 [Mus musculus]
         (173 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

14057                                                                 236   5e-63
25697                                                                 212   7e-56
30741                                                                  35   0.013
19962                                                                  32   0.19 
29613                                                                  30   0.35 
15655                                                                  30   0.48 
11098                                                                  29   0.81 
>14057
          Length = 1377

 Score =  236 bits (601), Expect = 5e-63,   Method: Compositional matrix adjust.
 Identities = 107/170 (62%), Positives = 137/170 (80%)
 Frame = +2

Query: 3   RMNRPAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEKEG 62
           +  RP P E+ +KNMRFLIT  PT++T++K+IEEL+K+G   +VRVC+ TY   +++K G
Sbjct: 665 KARRPEPAEIEFKNMRFLITDRPTDSTIDKYIEELQKHGAKHVVRVCDPTYSREVLQKAG 844

Query: 63  IHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALIEG 122
           I VLDW FDDG+PP N++V +W +L+K +F+EEPGCC+AVHCVAGLGRAPVLVA+AL+E 
Sbjct: 845 IDVLDWQFDDGSPPPNEVVGNWFNLLKARFKEEPGCCVAVHCVAGLGRAPVLVAIALMEA 1024

Query: 123 GMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFKDSNGHRNNCCI 172
           GMKYEDAV+ IRQKRRGA NSKQL YL+ YRPK RLR  + NGH + C I
Sbjct: 1025GMKYEDAVELIRQKRRGAINSKQLSYLQHYRPKSRLR-HNRNGH-SQCLI 1168
>25697
          Length = 470

 Score =  212 bits (539), Expect = 7e-56,   Method: Compositional matrix adjust.
 Identities = 96/150 (64%), Positives = 121/150 (80%), Gaps = 1/150 (0%)
 Frame = +1

Query: 18  RFLITHNPTNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEKEGIHVLDWPFDDGAPPS 77
           RFLIT  PT++TL+KFIEEL+K+G   +VRVC+ TY    +E EGI V+DW FDDG+PP 
Sbjct: 1   RFLITDRPTDSTLDKFIEELQKHGARHVVRVCDPTYSKEKLETEGIDVMDWQFDDGSPPP 180

Query: 78  NQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALIEGGMKYEDAVQFIRQKR 137
             +V +W +L+K  F+++PGCC+AVHCVAGLGRAPVLVA+AL+E GMKYEDAV+ IR+KR
Sbjct: 181 KDVVGNWFNLLKASFKDDPGCCVAVHCVAGLGRAPVLVAIALMEAGMKYEDAVELIRRKR 360

Query: 138 RGAFNSKQLLYLEKYRPKMRLRFK-DSNGH 166
           RGA NSKQL YL+ YRP+ RLR K + NGH
Sbjct: 361 RGAINSKQLSYLQHYRPRSRLRSKANRNGH 450
>30741
          Length = 506

 Score = 35.4 bits (80), Expect = 0.013,   Method: Compositional matrix adjust.
 Identities = 17/54 (31%), Positives = 26/54 (48%)
 Frame = -3

Query: 64  HVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVAL 117
           H + WP D G P    ++ +++S V+            VHC AG+GR    +AL
Sbjct: 405 HFMRWP-DHGCPERTSMLLNFVSSVRAHMPHTGAGPTLVHCSAGVGRTGTFIAL 247
>19962
          Length = 410

 Score = 31.6 bits (70), Expect = 0.19,   Method: Compositional matrix adjust.
 Identities = 24/80 (30%), Positives = 34/80 (42%)
 Frame = +1

Query: 59  EKEGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALA 118
           E   +H   WP D G P    +V  W S V  +  +  G  + VHC AG+GR    +AL 
Sbjct: 127 EVHLLHFTAWP-DHGVPCPVTLVRFW-SYVTRQPAQLSGPLL-VHCSAGIGRTGTYIALD 297

Query: 119 LIEGGMKYEDAVQFIRQKRR 138
           ++    +    V      RR
Sbjct: 298 MLTHQAETTGKVSVFPTVRR 357
>29613
          Length = 425

 Score = 30.4 bits (67), Expect = 0.35,   Method: Compositional matrix adjust.
 Identities = 18/55 (32%), Positives = 25/55 (45%), Gaps = 2/55 (3%)
 Frame = -2

Query: 82  DDWLSLVKIKFREEPGCC--IAVHCVAGLGRAPVLVALALIEGGMKYEDAVQFIR 134
           DD L  +     E  GC   + VHC AG+GR    +AL  +         +QF+R
Sbjct: 241 DDVLDFISSVRLESRGCQGPMVVHCSAGVGRTGTFIALDFL---------MQFVR 104
>15655
          Length = 467

 Score = 30.0 bits (66), Expect = 0.48,   Method: Compositional matrix adjust.
 Identities = 24/100 (24%), Positives = 41/100 (41%), Gaps = 11/100 (11%)
 Frame = +1

Query: 31  NKFIEELKKYGVTTIVRVCEATYDTTLVEKEGIHVLDWPFDDGAPPSNQIVDDWLSLVKI 90
           NK ++  K Y  T ++     T      E   +  + WP D G PP+   +D    + ++
Sbjct: 88  NKSVQTYKNYVETKLI--LRNTETDEWREVTHLQFISWP-DYGIPPATGFLDFLFHVREV 258

Query: 91  K----------FREEP-GCCIAVHCVAGLGRAPVLVALAL 119
           +          +   P G  I VHC AG+GR    + + +
Sbjct: 259 QASATTKMGASWAGHPLGPPIVVHCSAGIGRTGTFITIDI 378
>11098
          Length = 1151

 Score = 29.3 bits (64), Expect = 0.81,   Method: Compositional matrix adjust.
 Identities = 18/62 (29%), Positives = 35/62 (56%), Gaps = 3/62 (4%)
 Frame = -3

Query: 31  NKFIEELKKYGVTTIVRVCEATYDTTL--VEKEGIHVLDWPFDDGAPPSNQI-VDDWLSL 87
           N+F+  +K + V  I+  C  T+D  L   EK+ ++V  +   +G+P  +   VD+ +SL
Sbjct: 948 NEFVPFIKNFDVDEIMNFCTFTFDKQLFGTEKDVLYVCTYVPPEGSPFYSHFGVDNGISL 769

Query: 88  VK 89
           ++
Sbjct: 768 LE 763
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|22095023|ref|NP_033183.1| mitogen-activated protein
kinase kinase 4 [Mus musculus]
         (397 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

13840                                                                 237   6e-63
21210                                                                 182   2e-46
18921                                                                 140   9e-34
00300                                                                 116   2e-26
12721                                                                 112   2e-25
13592                                                                  99   3e-21
19094                                                                  84   1e-20
13212                                                                  94   1e-19
01707                                                                  89   3e-18
31885                                                                  88   6e-18
14420                                                                  87   8e-18
01060                                                                  80   2e-15
06405                                                                  78   5e-15
09606                                                                  76   3e-14
14126                                                                  70   2e-12
12786                                                                  69   2e-12
19761                                                                  69   3e-12
01718                                                                  69   5e-12
09007                                                                  68   7e-12
01392                                                                  67   9e-12
04852                                                                  65   5e-11
00715                                                                  64   1e-10
11185                                                                  63   2e-10
21808                                                                  62   3e-10
30755                                                                  62   4e-10
26560                                                                  62   5e-10
07291                                                                  60   2e-09
03240                                                                  59   3e-09
14116                                                                  58   8e-09
18484                                                                  58   8e-09
19301                                                                  57   1e-08
15910                                                                  56   2e-08
01756                                                                  55   4e-08
00392                                                                  53   2e-07
11780                                                                  52   4e-07
26711                                                                  52   5e-07
28638                                                                  51   7e-07
07940                                                                  51   8e-07
16708                                                                  50   1e-06
04591                                                                  50   2e-06
01966                                                                  50   2e-06
07836                                                                  50   2e-06
17300                                                                  49   5e-06
21433                                                                  48   7e-06
17253                                                                  48   8e-06
12672                                                                  47   9e-06
28157                                                                  47   2e-05
13066                                                                  46   2e-05
04138                                                                  46   2e-05
29581                                                                  46   3e-05
27405                                                                  46   3e-05
18996                                                                  45   6e-05
21079                                                                  44   1e-04
17975                                                                  44   1e-04
37063                                                                  44   1e-04
03508                                                                  43   2e-04
25019                                                                  43   2e-04
37602                                                                  42   6e-04
20640                                                                  40   0.001
08294                                                                  39   0.005
07833                                                                  37   0.011
00486                                                                  37   0.013
11404                                                                  37   0.016
27546                                                                  36   0.023
14477                                                                  36   0.025
36481                                                                  35   0.051
20152                                                                  35   0.069
27274                                                                  34   0.085
32000                                                                  34   0.097
17637                                                                  34   0.12 
18663                                                                  34   0.13 
32691                                                                  33   0.28 
29590                                                                  32   0.34 
32957                                                                  32   0.37 
26156                                                                  32   0.40 
20559                                                                  31   0.78 
21800                                                                  31   0.90 
13305                                                                  31   1.1  
26874                                                                  31   1.1  
29360                                                                  30   1.8  
01106                                                                  30   1.9  
15549                                                                  28   4.7  
16350                                                                  28   4.9  
31489                                                                  28   5.6  
31120                                                                  28   6.0  
22398                                                                  28   7.9  
20160                                                                  28   8.5  
>13840
          Length = 446

 Score =  237 bits (605), Expect = 6e-63,   Method: Compositional matrix adjust.
 Identities = 106/147 (72%), Positives = 130/147 (88%)
 Frame = -1

Query: 82  SGKLKISPEQHWDFTAEDLKDLGEIGRGAYGSVNKMVHKPSGQIMAVKRIRSTVDEKEQK 141
           +GKL+I P + +DFT+ED++D+GEIGRG YG+VNKM HK +  +MAVKRIRSTV+E+EQK
Sbjct: 443 TGKLQIYPGKEYDFTSEDMQDMGEIGRGNYGTVNKMRHKITSTVMAVKRIRSTVEEREQK 264

Query: 142 QLLMDLDVVMRSSDCPYIVQFYGALFREGDCWICMELMSTSFDKFYKYVYSVLDDVIPEE 201
           QLLMDLDVVMRS++CP+IVQFYGALF+EGDCWICMELM TS DKFYK+VY  +   IPE 
Sbjct: 263 QLLMDLDVVMRSNNCPFIVQFYGALFKEGDCWICMELMETSLDKFYKFVYGEMQSSIPEN 84

Query: 202 ILGKITLATVKALNHLKENLKIIHRDI 228
           ILGKIT+AT+KALN+LKE L+IIHRD+
Sbjct: 83  ILGKITVATLKALNYLKEELRIIHRDV 3
>21210
          Length = 518

 Score =  182 bits (461), Expect = 2e-46,   Method: Compositional matrix adjust.
 Identities = 90/138 (65%), Positives = 104/138 (75%), Gaps = 5/138 (3%)
 Frame = +3

Query: 262 AGCRPYMAPERIDPSASRQGYDVRSDVWSLGITLYELATGRFPYPKWNSVFDQLTQVVKG 321
           AGCRPYMAPERIDP AS  GYDVRSDVWSLGITL ELATGRFPY KW S+FDQL QVV+G
Sbjct: 3   AGCRPYMAPERIDPRASSHGYDVRSDVWSLGITLMELATGRFPYRKWVSIFDQLQQVVRG 182

Query: 322 DPPQLSNSEEREFSPSFINFVNLCLTKDESKRPKYKELLKHPFILMYEERTVEVACYVCK 381
             P L +  +  FS  F+NFVN CLTKDE +RPKY +LL HPF+ +YEE+ V+VA YVC 
Sbjct: 183 VAPCLPH--DGAFSHDFVNFVNKCLTKDEKQRPKYNKLLAHPFVRLYEEQEVDVASYVCN 356

Query: 382 ILD-----QMPATPSSPM 394
           +LD     Q PA  + P+
Sbjct: 357 VLDKRKTLQNPAPLNPPL 410
>18921
          Length = 697

 Score =  140 bits (353), Expect = 9e-34,   Method: Compositional matrix adjust.
 Identities = 83/209 (39%), Positives = 120/209 (57%), Gaps = 2/209 (0%)
 Frame = +2

Query: 98  EDLKD-LGEIGRGAYGSVNKMVHKPSGQIMAVKRIRSTVDEKEQKQLLMDLDVVMRSSDC 156
           ED+ D LG++G G+YGSV K +HK +GQ++A+K++    D +E    ++    +M+  D 
Sbjct: 26  EDVFDILGKLGEGSYGSVFKSLHKETGQVLAIKQVPVDTDLQE----IIKEISIMQQCDS 193

Query: 157 PYIVQFYGALFREGDCWICMELMSTSFDKFYKYVYSVLDDVIPEEILGKITLATVKALNH 216
            YIV++YG+ F+  D WI ME            +  + +  + E  +  I   T+K L +
Sbjct: 194 KYIVKYYGSYFKNTDLWIVMEYCGAGS---VSDIMRLRNKTLVEREIATILYYTLKGLXY 364

Query: 217 LKENLKIIHRDIKPSNILLDRSGNIKLCDFGISGQLVDSIAKTRDAGCRPY-MAPERIDP 275
           L    KI HRDIK  NILL+  G+ KL DFG++GQL D++AK       PY MAPE I  
Sbjct: 365 LHSRRKI-HRDIKAGNILLNNEGHAKLADFGVAGQLTDTMAKRNTVIGTPYWMAPEVI-- 535

Query: 276 SASRQGYDVRSDVWSLGITLYELATGRFP 304
                GYD  +D+WSLGIT  E+A G+ P
Sbjct: 536 --QEIGYDCVADIWSLGITALEMAEGKPP 616
>00300
          Length = 2318

 Score =  116 bits (290), Expect = 2e-26,   Method: Compositional matrix adjust.
 Identities = 77/268 (28%), Positives = 134/268 (50%), Gaps = 4/268 (1%)
 Frame = -1

Query: 105  EIGRGAYGSVNKMVHKPSGQIMAVKRIRSTVDEKEQKQLLMDLDVVMRSSDCPYIVQFYG 164
            +IG G +G V   V+  +G++MA+K ++   ++ +Q + + D   +        +V++YG
Sbjct: 1637 KIGEGQFGKVYTAVNMSTGELMALKEMKFQPNDLQQLREMCDEIKIFEGIQHENLVKYYG 1458

Query: 165  ALFREGDCWICMELMSTSFDKFYKYVYSVLDDVIPEEILGKITLATVKALNHLKENLKII 224
                + +  + ME   T        +       +PE ++ + T   V A+NHL EN  I+
Sbjct: 1457 VEVHKDEMLMFMEYCDTG------TIEEAAKMGLPEYLIRRYTREIVLAVNHLHEN-SIV 1299

Query: 225  HRDIKPSNILLDRSGNIKLCDFGISGQLVDSIAKTRD----AGCRPYMAPERIDPSASRQ 280
            HRDIK +NI L  +G++KL DFG S +L        +     G   YMAPE +     + 
Sbjct: 1298 HRDIKGANIFLTSNGHVKLGDFGCSVKLKSHTTMPGEFHNLVGTTAYMAPE-VFTQNDQG 1122

Query: 281  GYDVRSDVWSLGITLYELATGRFPYPKWNSVFDQLTQVVKGDPPQLSNSEEREFSPSFIN 340
            GY   +D+WSLG  + E+ATG+ P+   ++ +  + +V  G  P + +S     S    +
Sbjct: 1121 GYGRAADIWSLGCVVIEMATGKRPWHDLDNNYQIMYKVGIGHKPAVPDS----LSVEGKH 954

Query: 341  FVNLCLTKDESKRPKYKELLKHPFILMY 368
            F++L +  D ++R    +LL H F  +Y
Sbjct: 953  FLDLIMCHDPAQRALASQLLDHTFTKVY 870
>12721
          Length = 821

 Score =  112 bits (280), Expect = 2e-25,   Method: Compositional matrix adjust.
 Identities = 87/292 (29%), Positives = 139/292 (47%), Gaps = 7/292 (2%)
 Frame = +1

Query: 69  PHIERLRTHSIESSGKLKISPEQHWDFTAEDLKDLGEIGRGAYGSVNKMVHKPSGQIMAV 128
           P  +RL      ++ ++ ++P     F    L D  +IG G+ G V     +  G+ MAV
Sbjct: 13  PEPQRLSHEQFRAALQMVVTPGDPRTF----LDDFMKIGEGSTGIVCIATSR-DGRQMAV 177

Query: 129 KRIRSTVDEKEQKQLLMDLDVVMRSSDCPYIVQFYGALFREGDCWICMELMSTSFDKFYK 188
           K++   + ++++++LL +  VVMR    P IV+ Y +     + W+ ME M         
Sbjct: 178 KKM--DLRKQQRRELLFNEVVVMRDYHHPNIVEMYNSYLVNDELWVVMEFMEGG------ 333

Query: 189 YVYSVLDDVIPEEILGKITLATV-----KALNHLKENLKIIHRDIKPSNILLDRSGNIKL 243
                L D++    + ++ +ATV     KAL  L  N  +IHRDIK  +ILL   G +KL
Sbjct: 334 ----ALTDIVTNNRMDEVQIATVCRACLKALAFLHAN-GVIHRDIKSDSILLSHDGKVKL 498

Query: 244 CDFGISGQLVDSIAKTRDAGCRPY-MAPERIDPSASRQGYDVRSDVWSLGITLYELATGR 302
            DFG   Q+   + K +     PY MAPE I    SR  Y    D+WSLGI + E+    
Sbjct: 499 XDFGFCAQVTQDLQKRKSLVGTPYWMAPEVI----SRLPYGPEVDIWSLGIMVMEMIDAE 666

Query: 303 FPYPKWNS-VFDQLTQVVKGDPPQLSNSEEREFSPSFINFVNLCLTKDESKR 353
            P+  +N      + ++    PP+L N+   + SP    F++  L +D  +R
Sbjct: 667 PPF--FNEPPLQAMRRIRDMPPPKLRNTH--KISPRLQGFIDRMLVRDPHQR 810
>13592
          Length = 980

 Score = 99.0 bits (245), Expect = 3e-21,   Method: Compositional matrix adjust.
 Identities = 76/272 (27%), Positives = 134/272 (49%), Gaps = 12/272 (4%)
 Frame = +2

Query: 105 EIGRGAYGSVNKMVHKPSGQIMAVKRIRSTVDEKEQKQLLMDLDVVMRSSDCPYIVQFYG 164
           +IG+G +G V   V+  +G++MA+K I     E    + + +   ++       +V++YG
Sbjct: 5   KIGQGRFGKVYTAVNNNTGELMAMKEIAIQPGETRALKNVAEELKILEGIKHKNLVRYYG 184

Query: 165 ALFREGDCWICMELMS-TSFDKFYKYVYSVLDDVIPEEILGKITLATVKALNHLKENLKI 223
                 +  I MEL S  + +   +     L   +PE +  + T   +  +  L ++  I
Sbjct: 185 IEVHREELLIFMELCSEGTLESLVE-----LTGGLPEALSRRFTAQLLSGVAELHKH-GI 346

Query: 224 IHRDIKPSNI-LLDRSGNIKLCDFG----------ISGQLVDSIAKTRDAGCRPYMAPER 272
           +HRDIK +NI L+D S ++KL DFG          + G+L   +      G + YMAPE 
Sbjct: 347 VHRDIKTANIFLVDGSNSLKLGDFGSAVKIQAHTTVPGELQGYV------GTQAYMAPEV 508

Query: 273 IDPSASRQGYDVRSDVWSLGITLYELATGRFPYPKWNSVFDQLTQVVKGDPPQLSNSEER 332
              + S  G+   +D+WS+G  + E+A+G+ P+ +++S F  + +V  G+ PQ   S  +
Sbjct: 509 FTKTNS-DGHGRLADIWSVGCVVVEMASGKRPWAQFDSNFQIMFKVGMGEKPQAPESLSQ 685

Query: 333 EFSPSFINFVNLCLTKDESKRPKYKELLKHPF 364
           E      +F++ CL  D  +R    ELL+  F
Sbjct: 686 EGH----DFIDHCLQHDPKQRLSAIELLEQNF 769
>19094
          Length = 898

 Score = 83.6 bits (205), Expect(2) = 1e-20,   Method: Compositional matrix adjust.
 Identities = 49/110 (44%), Positives = 63/110 (57%), Gaps = 1/110 (0%)
 Frame = +1

Query: 195 DDVIPEEILGKITLATVKALNHLKENLKIIHRDIKPSNILLDRSGNIKLCDFGISGQLVD 254
           +  + E  +  I   T+K L +L    KI HRDIK  NILL+  G+ KL DFG++GQL D
Sbjct: 40  NKTLVEREIATILYYTLKGL*YLHSRRKI-HRDIKAGNILLNNEGHAKLADFGVAGQLTD 216

Query: 255 SIAKTRDAGCRPY-MAPERIDPSASRQGYDVRSDVWSLGITLYELATGRF 303
           ++AK       PY MAPE I       GYD  +D+WSLGIT  E+A G  
Sbjct: 217 TMAKRNTVIGTPYWMAPEVIQEI----GYDCVADIWSLGITALEMAEGNL 354

 Score = 33.9 bits (76), Expect(2) = 1e-20,   Method: Compositional matrix adjust.
 Identities = 19/54 (35%), Positives = 27/54 (50%)
 Frame = +3

Query: 333 EFSPSFINFVNLCLTKDESKRPKYKELLKHPFILMYEERTVEVACYVCKILDQM 386
           ++S  FI+FV+ CL K+   R    +LL+H FI   E          C+IL  M
Sbjct: 432 KWSTEFIDFVSKCLVKNPENRATAVDLLQHDFIKKAE---------ACEILQAM 566
>13212
          Length = 1067

 Score = 94.0 bits (232), Expect = 1e-19,   Method: Compositional matrix adjust.
 Identities = 56/146 (38%), Positives = 83/146 (56%), Gaps = 3/146 (2%)
 Frame = -1

Query: 223 IIHRDIKPSNILLDRSGNIKLCDFGISGQLVDSIAKTRDA--GCRPYMAPERIDPSASRQ 280
           +IHRDIK  N+LL   G +KL DFG+S +   +  K RD   G   +MAPE +     + 
Sbjct: 917 VIHRDIKAGNVLLTIDGEVKLADFGVSAKNTQTQQK-RDTFIGTPYWMAPEVVLCETLKD 741

Query: 281 G-YDVRSDVWSLGITLYELATGRFPYPKWNSVFDQLTQVVKGDPPQLSNSEEREFSPSFI 339
             YD ++D+WSLG+TL E A    P  + + +   L ++ K DPP L     ++++  F 
Sbjct: 740 TPYDFKADIWSLGVTLIEFAQIEPPNKEMHPMR-VLIKIHKSDPPTLEKP--KKWTKLFK 570

Query: 340 NFVNLCLTKDESKRPKYKELLKHPFI 365
           +F+  CL KD + RP   ELL+HPF+
Sbjct: 569 DFIAKCLVKDPNLRPTAAELLEHPFM 492
>01707
          Length = 757

 Score = 89.0 bits (219), Expect = 3e-18,   Method: Compositional matrix adjust.
 Identities = 66/225 (29%), Positives = 111/225 (49%), Gaps = 2/225 (0%)
 Frame = +1

Query: 98  EDLKDLGEIGRGAYGSVNKMVHKPSGQIMAVKRIRSTVDEKEQKQLLMDLDVVMRSSDCP 157
           E  + +G+IG G+YG V K  +K + Q++A+K+   + D+   K++ M    +++    P
Sbjct: 64  EKYEKIGKIGEGSYGVVFKCRNKETSQLVAIKKFVESEDDPLIKKIAMREIRMLKQLKHP 243

Query: 158 YIVQFYGALFREGDCWICMELMS-TSFDKFYKYVYSVLDDVIPEEILGKITLATVKALNH 216
            +V+      R+    +  + +  T  ++  +Y        +PE ++ +I   T+ A+N 
Sbjct: 244 NLVRLIEVFRRKKRLHLVFDYVDHTLLNELDRYPRG-----LPEPMVKRIIYQTLLAVNF 408

Query: 217 LKENLKIIHRDIKPSNILLDRSGNIKLCDFGISGQLVDSIAKTRD-AGCRPYMAPERIDP 275
             +    IHRD+KP NIL+ R G +KLCDFG +  L     +  D    R Y APE +  
Sbjct: 409 CHQ-YNTIHRDVKPENILITRQGQVKLCDFGFARILTGPGDEYTDYVATRWYRAPELL-- 579

Query: 276 SASRQGYDVRSDVWSLGITLYELATGRFPYPKWNSVFDQLTQVVK 320
                 Y    DVW++G    EL TG+  +P  + V DQL  + K
Sbjct: 580 -VGDTQYGPPVDVWAIGCVFAELLTGQALWPGRSDV-DQLHLIRK 708
>31885
          Length = 529

 Score = 88.2 bits (217), Expect = 6e-18,   Method: Compositional matrix adjust.
 Identities = 56/153 (36%), Positives = 81/153 (52%), Gaps = 2/153 (1%)
 Frame = -2

Query: 155 DCPYIVQFYGALFREGDCWICMELMSTSFDKFYKYVYSVLDDVIPEEILGKITLATVK-A 213
           D P++V  + A   E D ++ ++L            Y +  +V   E   K  L  +   
Sbjct: 498 DHPFLVNLWYAFQDEEDLFMVVDLFLGG-----DLRYHMQQEVSFREDCVKFYLCQLALV 334

Query: 214 LNHLKENLKIIHRDIKPSNILLDRSGNIKLCDFGISGQLVDSIAKTRDAGCRPYMAPERI 273
           L++L+   KI+HRDIKP NILLD  G+  + DF I+ QL D    T  +G RPYMAPE  
Sbjct: 333 LDYLRSQ-KIVHRDIKPDNILLDEQGHCHVTDFNIATQLEDDELATSTSGTRPYMAPEVY 157

Query: 274 DPSAS-RQGYDVRSDVWSLGITLYELATGRFPY 305
             + + R+GY    D WSLG++L+EL   R P+
Sbjct: 156 GVAINERRGYGFPVDWWSLGVSLFELLKKRRPF 58
>14420
          Length = 528

 Score = 87.4 bits (215), Expect = 8e-18,   Method: Compositional matrix adjust.
 Identities = 58/177 (32%), Positives = 90/177 (50%), Gaps = 6/177 (3%)
 Frame = +2

Query: 135 VDEKEQKQLLMDLDVVMRSSDCPYIVQFYGALFREGDCWICMELMSTSFDKFYKYVYSVL 194
           + ++ +K+L+++  +VMR +  P IV +  +     + W+ ME ++             L
Sbjct: 14  LSQQPKKELIINEILVMRENQNPNIVNYLDSYLVGEELWVVMEFLAGG----------SL 163

Query: 195 DDVIPEEILGKITLATV-----KALNHLKENLKIIHRDIKPSNILLDRSGNIKLCDFGIS 249
            DV+ E  + +  +A V     +AL  L EN ++IHRDIK  NILL   G++KL DFG  
Sbjct: 164 TDVVTETCMDEGQIAAVCRECLQALEFLHEN-QVIHRDIKSDNILLGMDGSVKLTDFGFC 340

Query: 250 GQLVDSIAKTRDAGCRPY-MAPERIDPSASRQGYDVRSDVWSLGITLYELATGRFPY 305
            QL    +K       PY MAPE +    +R+ Y    D+WSLG+   E+  G  PY
Sbjct: 341 AQLSPEQSKRSTMVGTPYWMAPEVV----TRKQYGPTVDIWSLGVMCIEMIEGEPPY 499
>01060
          Length = 1800

 Score = 79.7 bits (195), Expect = 2e-15,   Method: Compositional matrix adjust.
 Identities = 77/298 (25%), Positives = 131/298 (43%), Gaps = 30/298 (10%)
 Frame = +1

Query: 99  DLKDLGEIGRGAYGSVNKMVHKPSGQIMAVKRIRSTVDEKEQKQLLMDLDVVMRSSDCPY 158
           DL D  +IG G YG V K  H+ +G+ +A+K+IR    E       +    ++R      
Sbjct: 76  DLTDFQKIGEGTYGVVYKCRHRATGRKLAMKKIRLRGSEDGVPSSAIREIAMLRELRHTN 255

Query: 159 IVQFYGALFREGDCWICMELMSTSF----DKFYKYVYSVLDDVIPEEILGKITLATVKAL 214
           IV     +  +   ++  E +S       DKF + V      V+   ++       V  +
Sbjct: 256 IVCLEDVIMEDERLFLVFEFLSMDLKMYIDKFPEGV------VLDRRLVKSYVFQIVTGI 417

Query: 215 NHLKENLKIIHRDIKPSNILLDRSGNIKLCDFGISGQLVDSI-AKTRDAGCRPYMAPERI 273
               +  +I+HRD+KP N+L++ +G IK+ DFG++      + A T +     Y APE I
Sbjct: 418 XFCHQR-RIVHRDLKPQNLLINHTGAIKIADFGMARTFALPVRAYTHEVVTLWYRAPE-I 591

Query: 274 DPSASRQGYDVRSDVWSLGITLYELATGRFPYPKWNSVFDQLTQVVK--GDPPQLSNSEE 331
              AS+  Y    DVWS+G T++     R P  K +S  DQL ++ +  G P + +  E 
Sbjct: 592 LMGASK--YSTPVDVWSIG-TIFADMLIRTPIFKGDSEIDQLFKIFRIIGTPTEQTWPEF 762

Query: 332 REFSPSF-----------------------INFVNLCLTKDESKRPKYKELLKHPFIL 366
            +  P+F                       ++ +   L  D ++R   K++L+H + L
Sbjct: 763 HKL-PAFNGMFPLWKEGKLSETLTDLDSLGLDLIERTLKCDPAQRISCKKMLQHAYFL 933
>06405
          Length = 1965

 Score = 78.2 bits (191), Expect = 5e-15,   Method: Compositional matrix adjust.
 Identities = 78/299 (26%), Positives = 128/299 (42%), Gaps = 12/299 (4%)
 Frame = +1

Query: 87  ISPE-QHWDFTAEDLKDLGEIGRGAYGSVNKMVHKPSGQIMAVKRIRSTVDEKEQKQLLM 145
           +SPE   W+    ++     +G G YG V + + K   +I+AVK +      KE    L 
Sbjct: 223 VSPEPDRWEIERTEIAMKHRLGGGQYGDVYEAMWKRYNKIVAVKTL------KEDTMALN 384

Query: 146 DL---DVVMRSSDCPYIVQFYGALFREGDCWICMELMSTSFDKFYKYVYSVLDDVIPEEI 202
           D      +M+    P +VQ  G   RE   +I  E M         Y+ S   +      
Sbjct: 385 DFLEEAAIMKEMKHPNLVQLLGVCTREPPFYIVTEFMP--HGNLLDYLRSSTREENGPTA 558

Query: 203 LGKITLATVKALNHLKENLKIIHRDIKPSNILLDRSGNIKLCDFGISGQLVDSIAKTRDA 262
           L  +       + +L E    IHRD+   N L+  S  +K+ DFG++  + D        
Sbjct: 559 LMYMATQIASGMAYL-ETKNFIHRDLAARNCLVADSNMVKVADFGLARLMKDDTYTAHIG 735

Query: 263 GCRP--YMAPERIDPSASRQGYDVRSDVWSLGITLYELAT-GRFPYP--KWNSVFDQLTQ 317
              P  + APE +    +   +  RSD+W+ G+ L+ELAT G  PYP  +   V+  L +
Sbjct: 736 AKFPIKWTAPEGL----AFNRFSTRSDIWAFGVLLWELATYGMSPYPGVELTEVYHLLER 903

Query: 318 VVKGDPPQLSNSEEREFSPSFINFVNL-CLTKDESKRPKYKELLKHPFIL--MYEERTV 373
             + + P          +P+ +  + L C   D   RP +KE+    F+L  M+E+ ++
Sbjct: 904 GYRMERPP--------GTPADVYILMLKCWQWDPKDRPTFKEIH---FLLENMFEKSSI 1047
>09606
          Length = 1300

 Score = 75.9 bits (185), Expect = 3e-14,   Method: Compositional matrix adjust.
 Identities = 73/289 (25%), Positives = 124/289 (42%), Gaps = 29/289 (10%)
 Frame = -3

Query: 105  EIGRGAYGSVNKMVHKPSGQIMAVKRIRSTVDEKEQKQLLMDLDVVMRSSDCPYIVQFYG 164
            E+G+G +  + K   K +   +A+  I      +    + M  D+       P +VQF+ 
Sbjct: 1094 ELGKGEHSIIYKGRRKGTINFVAIHCIEKCKRPEVTNTVRMTHDI-----SHPNVVQFHE 930

Query: 165  ALFREGDCWICMELMSTSFDKFYKYVYSVL--DDVIPEEILGKITLATVKALNHLKENLK 222
                    W+ +EL +         +  +L  D  +PE  +    +  V  L+++  +L 
Sbjct: 929  WYETSNHLWLVVELCTGG------SLADILAQDHHLPETSIRDFGIHLVTGLHYI-HSLG 771

Query: 223  IIHRDIKPSNILLDRSGNIKLCDFGISG-------QLVDSIAKTRD-------------- 261
            I+  D++PS +LLD SG +K  DFG+S        +L    A+  D              
Sbjct: 770  ILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEAGDQWNIQSAEEMMKQV 591

Query: 262  --AGCRPYMAPERIDPSASRQGYD--VRSDVWSLGITLYELATGRFPYPKWNSVFDQLTQ 317
              +G   YMAPE        QG +  + SD+W+LG   YE+ +G  P+        +   
Sbjct: 590  PTSGSPTYMAPEVF------QGAEPSIMSDLWALGCVFYEMFSGHPPFLGETYDITKDKV 429

Query: 318  VVKGDP-PQLSNSE-EREFSPSFINFVNLCLTKDESKRPKYKELLKHPF 364
            + K  P P++  S    + SP F+N +   L KD ++R  +  L+KH F
Sbjct: 428  LNKEFPLPKVKGSRLSAKPSPEFLNLLESLLQKDSTRRLSWASLVKHAF 282
>14126
          Length = 1265

 Score = 69.7 bits (169), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 69/273 (25%), Positives = 124/273 (45%), Gaps = 15/273 (5%)
 Frame = +3

Query: 80  ESSGKLKISPEQHWDFTAEDLKDLGEIGRGAYGSVNKMVH-KPSGQIMAVKRIRSTVDEK 138
           ES+ K+     +  D T +  +++  IG GAYG+V K    +  G+ +A+KRIR  ++  
Sbjct: 147 ESAAKMS----RRRDSTEQKYEEVAVIGNGAYGTVYKARDLRNQGEFVAMKRIR--LNNT 308

Query: 139 EQKQLLMDLDVV-----MRSSDCPYIVQFYGALFRE-GDCWICMELMSTSFDK-FYKYVY 191
           E+   +M +  +     +   + P +V+          D  I + L+    +     Y+ 
Sbjct: 309 EEGMPMMAIREISMLKQLEQYEHPNVVRLLDVSHNTITDREIRLNLVFEYIEHDLATYLA 488

Query: 192 SVLDDVIPEEILGKITLATVKALNHLKENLKIIHRDIKPSNILLDRSGNIKLCDFGISGQ 251
                 +  + +  + L  +  ++ L  N +I+HRD+KP N+L+ + G +KL DFG++  
Sbjct: 489 KCPSPGLGPDRIKDLMLQLLNGVDFLHSN-RIVHRDLKPQNLLISKDGRLKLADFGLARI 665

Query: 252 LVDSIAKTRDAGCRPYMAPERIDPSASRQGYDVRSDVWSLGITLYELATGRFPYPKWNSV 311
               +A T       Y +PE +     +  Y    D+WS G    EL T R  + K +S 
Sbjct: 666 YSFHMALTTVVVTLWYRSPEVL----MQAEYGTSVDIWSCGCIFAELFTRRALF-KGSSE 830

Query: 312 FDQLTQVVK-------GDPPQLSNSEEREFSPS 337
           FDQL ++ +       GD P+  +     F P+
Sbjct: 831 FDQLKKIFEVIGLPPAGDWPEGVSVHRNSFRPT 929
>12786
          Length = 460

 Score = 69.3 bits (168), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 47/117 (40%), Positives = 60/117 (51%), Gaps = 19/117 (16%)
 Frame = -3

Query: 208 LATVKALNHLKENLKIIHRDIKPSNILLDRSGNIKLCDFGISGQLVD---SIAKTRDAGC 264
           L  VKAL+    N  +IH D+KP+N +L  +GN+KL DFGI+  L     S+ K    G 
Sbjct: 380 LRAVKALH----NEGVIHSDLKPANFML-VAGNLKLIDFGIANTLQQDKTSVLKDSRVGT 216

Query: 265 RPYMAPERI--------DPSASRQGY--------DVRSDVWSLGITLYELATGRFPY 305
             YM+PE I        D S    G+         VRSDVWSLG  LY +  GR P+
Sbjct: 215 PSYMSPEAIMAACDDSADDSMEEDGHRTKPKYKVGVRSDVWSLGCILYNMVYGRTPF 45
>19761
          Length = 473

 Score = 68.9 bits (167), Expect = 3e-12,   Method: Compositional matrix adjust.
 Identities = 48/154 (31%), Positives = 83/154 (53%), Gaps = 2/154 (1%)
 Frame = -3

Query: 198 IPEEILGKITLATVKALNHLKENLKII-HRDIKPSNILLDRSGNIKLCDFGISGQLVD-S 255
           +PE ++    + T  ALN++  +  +I HRD+KP NI +   G+++L D G++ +L   +
Sbjct: 432 LPERLIVCWLMQTASALNYMHTHTPVILHRDLKPQNIYVTEKGDVRLGDLGLARKLTGPA 253

Query: 256 IAKTRDAGCRPYMAPERIDPSASRQGYDVRSDVWSLGITLYELATGRFPYPKWNSVFDQL 315
              T   G   Y++PE +    S+Q Y+ +SD+WSLG   Y++ TG+    +   +F  L
Sbjct: 252 DFATSQVGTIMYLSPEIL----SQQPYNSKSDIWSLGCVFYDI-TGKKGSDEMGVMF-LL 91

Query: 316 TQVVKGDPPQLSNSEEREFSPSFINFVNLCLTKD 349
            QV+ G    L +   +EF  +    ++  LTKD
Sbjct: 90  VQVMGGRKLPLPDHYSQEFRDT----ISRMLTKD 1
>01718
          Length = 959

 Score = 68.6 bits (166), Expect = 5e-12,   Method: Compositional matrix adjust.
 Identities = 68/276 (24%), Positives = 128/276 (46%), Gaps = 8/276 (2%)
 Frame = +3

Query: 94  DFTAEDLKDLGEIGRGAYGSVNKMVHKPSGQIMAVKRIRSTVDEKEQKQLLMDLDVVMRS 153
           DF  E      +IG G +  V K+ H+ +GQ+MA+K    T +     + +  L+ +  +
Sbjct: 153 DFICE------KIGAGFFSEVFKVTHRITGQVMALKMNTMTSNRHNMLREVQLLNRLQHA 314

Query: 154 SDCPYIVQFYGALFREGDCWICMELM-STSFDKFYKYVYSVLDDVIPEEILGKITLATVK 212
           +    I++F G    EG      E + S + ++  +      D+ +P     ++TL   +
Sbjct: 315 N----ILRFMGVCVHEGQLHALTEYIPSGNLEQLLEKK----DEELPWTQRIQLTLGLAR 470

Query: 213 ALNHLKENLKIIHRDIKPSNILLDRSGN----IKLCDFGISGQLVDSIAKTR--DAGCRP 266
            L++L    + IHRD+   NIL+ R  N      + DFG++ ++ D + K +    G   
Sbjct: 471 GLDYLHST-RFIHRDLTSKNILIRREDNHGYHAVIADFGLATKIPDPLDKEKLPTVGSPY 647

Query: 267 YMAPERIDPSASRQGYDVRSDVWSLGITLYELATGRFPYPKWNSVFDQLTQVVKGDPPQL 326
           +MAPE ++       Y+ R+D++S+GI + E+ T R P        D + ++       +
Sbjct: 648 WMAPEVLNG----HFYNERADLFSVGIIMCEI-TARIPADP-----DIMPRMNNFGVDYV 797

Query: 327 SNSEEREFSP-SFINFVNLCLTKDESKRPKYKELLK 361
           + SE   + P  ++     C   D  KRP+  E+++
Sbjct: 798 ALSEMISYCPLDYLQLAFKCCQVDPQKRPRGVEIIE 905
>09007
          Length = 1440

 Score = 67.8 bits (164), Expect = 7e-12,   Method: Compositional matrix adjust.
 Identities = 75/287 (26%), Positives = 131/287 (45%), Gaps = 17/287 (5%)
 Frame = -1

Query: 106 IGRGAYGSVNKMVHKP-SGQ--IMAVKRIRSTVDEKEQKQLLMDLDVVMRSSDCPYIVQF 162
           +G+G +G+V + +    SG+   +AVK +      K+ ++ L +   +M+  D   IV+ 
Sbjct: 855 LGQGHFGTVRQAIWTAESGEKVQVAVKCLSKDKIHKDGQEFLKE-TAIMQMLDHENIVRV 679

Query: 163 YGALFREG-DCWICMELMST-SFDKFYKYVYSVLDDVIPEEILGKITLATVKALNHLKEN 220
           YG +   G D  +  EL    S  +  K V + +D  +P   L   +      +++L E+
Sbjct: 678 YGVVMDNGADIMLVTELAPMRSLLECVKEVSARVDFSVPR--LCDFSQQVCDGMSYL-ES 508

Query: 221 LKIIHRDIKPSNILLDRSGNIKLCDFGISGQLVDSIAKTRDAGCRPYMAPERID------ 274
            +++HRD+   NILL     +K+ D G+SG L         AG   Y + + I       
Sbjct: 507 KRLVHRDLAARNILLFSKSKVKISDVGVSGAL--------GAGKEYYQSQQTIHLQNAVA 352

Query: 275 ---PSASRQ-GYDVRSDVWSLGITLYELATGRF-PYPKWNSVFDQLTQVVKGDPPQLSNS 329
              P + R   +   SDVW+ G+ L+E  T  F P+   N    Q+ + V  D PQ    
Sbjct: 351 WCAPESFRNLCFSSASDVWAFGVLLWEFFTHGFQPWAGLNG--QQIMEAV--DAPQSQRL 184

Query: 330 EEREFSPSFINFVNL-CLTKDESKRPKYKELLKHPFILMYEERTVEV 375
           E+ +  P     V L C  ++  +RP + +L    F+ + + R ++V
Sbjct: 183 EQPDLCPKEYYAVMLKCWEQEPQRRPTFSQL----FLTLPQIRPIQV 55
>01392
          Length = 1806

 Score = 67.4 bits (163), Expect = 9e-12,   Method: Compositional matrix adjust.
 Identities = 54/178 (30%), Positives = 78/178 (43%), Gaps = 23/178 (12%)
 Frame = -1

Query: 211  VKALNHLKENLKIIHRDIKPSNIL---LDRSGNIKLCDFGISGQLVDSIAKTRD------ 261
             +AL+ L     I HRD+KP NIL   LD    +K+CDF ++  +      T+       
Sbjct: 1761 ARALDFLHSK-GIAHRDLKPENILCEHLDDVVPVKICDFDLASGISCDGDGTKTPELLTP 1585

Query: 262  AGCRPYMAPERIDPSASRQ-GYDVRSDVWSLGITLYELATGRFPY-------PKWN---- 309
             G   YMAPE +D        YD R D+WSLGI LY +  G  P+         WN    
Sbjct: 1584 VGSAEYMAPEVVDAWVGDSFSYDKRCDLWSLGIILYIMLCGYPPFYGQCGEDCGWNRGEA 1405

Query: 310  --SVFDQLTQVVKGDPPQLSNSEEREFSPSFINFVNLCLTKDESKRPKYKELLKHPFI 365
                 D L   ++    +  + E    S S  + +   L ++  KR    ++LKHP+I
Sbjct: 1404 CHDCQDMLFNSIQDGHYKFPSQEWTSISSSAKDLIRHLLVREPRKRYSAADVLKHPWI 1231
>04852
          Length = 1462

 Score = 65.1 bits (157), Expect = 5e-11,   Method: Compositional matrix adjust.
 Identities = 67/272 (24%), Positives = 104/272 (38%), Gaps = 30/272 (11%)
 Frame = +1

Query: 121 PSGQIMAVKRIRSTVDEKEQKQLLMDLDV---VMRSSDCPYIVQFYGALFREGDCWICME 177
           P    +AVK +R  V   E++  + +L V   V +      IV F G   + G  W+ +E
Sbjct: 13  PKASTVAVKMLRDIVTAVEEQDFVQELQVMKAVKKMGSHINIVNFLGCCTQGGPLWVIVE 192

Query: 178 LMSTS---------------FDKFYK------YVYSVLDDVIPEEILGKITLATVKALNH 216
                               + KF        Y  +    VI  + L        + +  
Sbjct: 193 FAKNGNLRDFLESCRDGINGYGKFVSPQDPGWYTKTPGGHVIRRKNLLSYAFQIARGMEF 372

Query: 217 LKENLKIIHRDIKPSNILLDRSGNIKLCDFGISGQLVDSIAKTRDAGCRP--YMAPERID 274
           L    K IHRD+   N+L+     +K+ DFG+S        K R  G  P  +MAPE + 
Sbjct: 373 LASR-KCIHRDLAARNVLVTEEHVLKIADFGLS--RTGDYYKKRSGGRLPVKWMAPEAL- 540

Query: 275 PSASRQGYDVRSDVWSLGITLYEL-ATGRFPY---PKWNSVFDQLTQVVKGDPPQLSNSE 330
                  Y  +SDVWS G+ L+E+ + G  PY   P        L    +   P+L+   
Sbjct: 541 ---FDMRYTTKSDVWSFGVVLWEIFSLGGMPYASIPNEELYSKLLDDAYRMPRPELA--- 702

Query: 331 EREFSPSFINFVNLCLTKDESKRPKYKELLKH 362
               S +    +  C     S RP++ +L+ H
Sbjct: 703 ----SGNLYAIMERCWLNRPSDRPEFSQLVGH 786
>00715
          Length = 1788

 Score = 63.9 bits (154), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 51/178 (28%), Positives = 80/178 (44%), Gaps = 29/178 (16%)
 Frame = +1

Query: 206 ITLATVKALNHLKENLKIIHRDIKPSNILLDRSGNIKLCDFGISGQL------------- 252
           + L   + L++L  ++ I+H D+KP+N LL R   +++ DFG   QL             
Sbjct: 253 LALQMARGLHYL-HSINIVHLDLKPANCLLTRDLKLRIADFGCCHQLTPTGLDMGEREGG 429

Query: 253 ----------VDSIAKTRDAGCRPYMAPE---RIDPSASRQGYDVRSDVWSLGITLYELA 299
                     V    K   AG   Y APE    + PS       VRSDV+SLGITL+++ 
Sbjct: 430 MAGNELELTPVQGAWKNELAGTLAYRAPELLKGLQPS-------VRSDVYSLGITLWQMC 588

Query: 300 TGRFPY---PKWNSVFDQLTQVVKGDPPQLSNSEEREFSPSFINFVNLCLTKDESKRP 354
           T + PY   P    V+  +++ ++  PP   ++E+  F   F +    C  +    RP
Sbjct: 589 TRQGPYEGVPAHAVVYQVVSKDLRPCPP--PSTEDDPFEVMFRDLYTQCWARRVEDRP 756
>11185
          Length = 473

 Score = 62.8 bits (151), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 48/174 (27%), Positives = 71/174 (40%), Gaps = 25/174 (14%)
 Frame = +1

Query: 216 HLKENLKIIHRDIKPSNILLDRSGNIKLCDFGISG-------QLVDSIAKTRD------- 261
           H   +L I+  D++PS +LLD SG +K  DFG+S        +L    A+  D       
Sbjct: 43  HYIHSLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEAGDQWNIQSA 222

Query: 262 ---------AGCRPYMAPERIDPSASRQGYD--VRSDVWSLGITLYELATGRFPYPKWNS 310
                    +G   YMAPE        QG +  + SD+W+LG   YE+ +G         
Sbjct: 223 EEMMKQVPTSGSPTYMAPEVF------QGAEPSIMSDLWALGCVFYEMFSG--------- 357

Query: 311 VFDQLTQVVKGDPPQLSNSEEREFSPSFINFVNLCLTKDESKRPKYKELLKHPF 364
                   +   P           SP F+N +   L KD ++R  +  L+KH F
Sbjct: 358 ------SRLSAKP-----------SPEFLNLLESLLQKDSTRRLSWASLVKHAF 468
>21808
          Length = 1011

 Score = 62.4 bits (150), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 59/201 (29%), Positives = 98/201 (48%), Gaps = 5/201 (2%)
 Frame = +1

Query: 126 MAVKRIRS-TVDEKEQKQLLMDLDVVMRSSDCPYIVQFYGALFREGDCWICMELM-STSF 183
           +A+K ++S T+D K+     +    +M+    P ++Q Y    ++   +I  ELM + S 
Sbjct: 28  VAIKTLKSGTMDPKD----FLAEAQIMKKLRHPKLIQLYAVCTQDDPIFIITELMKNGSL 195

Query: 184 DKFYKYVYSVLDDVIPEEILGKITLATVKALNHLKENLKIIHRDIKPSNILLDRSGNIKL 243
            +F +    VL   +P  I   I       + +L E+   IHRD+   NIL+  +  +K+
Sbjct: 196 LEFLQGKGRVLK--LPALI--DIGAQIACGMAYL-ESQNYIHRDLAARNILVSDNNTVKI 360

Query: 244 CDFGISGQLVDSIAKTRDAGCRP--YMAPERIDPSASRQGYDVRSDVWSLGITLYELAT- 300
            DFG++  + +   + R     P  + APE    +A+   + ++SDVWS GI L E  T 
Sbjct: 361 ADFGLARVIKEDEYEARVGARFPIKWTAPE----AANYNRFTIKSDVWSFGILLTETVTY 528

Query: 301 GRFPYPKWNSVFDQLTQVVKG 321
           GR PYP   +  + L QV  G
Sbjct: 529 GRVPYPGMTNA-EVLHQVEHG 588
>30755
          Length = 1137

 Score = 62.0 bits (149), Expect = 4e-10,   Method: Compositional matrix adjust.
 Identities = 47/161 (29%), Positives = 76/161 (47%), Gaps = 6/161 (3%)
 Frame = +2

Query: 211 VKALNHLKENLKIIHRDIKPSNILLDRSGNIKLCDFGISGQLVDSIAKTRD-AGCRPYMA 269
           + AL +L     II+RD+K  N+LLD+ G+IK+ DFG+  + +     T+   G   Y+A
Sbjct: 62  ISALGYLHSQ-GIIYRDLKLENLLLDKDGHIKVADFGLCKEDITYGRTTKTFCGTPEYLA 238

Query: 270 PERIDPSASRQGYDVRSDVWSLGITLYELATGRFPYPKWNSVFDQLTQVVKGDPPQLSNS 329
           PE +D +     Y    D W  G+ +YE+  GR P+  +N   D L  ++  +  +    
Sbjct: 239 PEVLDDND----YGRAVDWWGTGVVMYEMICGRLPF--YNRDHDVLFTLILVEDVKFP-- 394

Query: 330 EEREFSPSFINFVNLCLTKDESKR-----PKYKELLKHPFI 365
             R  +    + ++  L KD   R        KE+  HPF 
Sbjct: 395 --RNITDEAKSLLSGLLAKDPRNRLGGGQDDVKEIQAHPFF 511
>26560
          Length = 398

 Score = 61.6 bits (148), Expect = 5e-10,   Method: Compositional matrix adjust.
 Identities = 35/100 (35%), Positives = 53/100 (53%), Gaps = 3/100 (3%)
 Frame = -1

Query: 213 ALNHLKENLKIIHRDIKPSNILLDRSGNIKLCDFGISGQLVDSIAKTR---DAGCRPYMA 269
            L H+     +++RD+KP+NILLD +G++++ D G    L    +K R     G   YMA
Sbjct: 320 GLEHMHSRF-VVYRDLKPANILLDENGHVRISDLG----LACDFSKKRPHASVGTHGYMA 156

Query: 270 PERIDPSASRQGYDVRSDVWSLGITLYELATGRFPYPKWN 309
           PE +      Q YD  +D +S G  LY+L  G  P+ + N
Sbjct: 155 PEVL---MKGQSYDSSADWFSFGCMLYKLLKGHSPFRQHN 45
>07291
          Length = 833

 Score = 59.7 bits (143), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 34/99 (34%), Positives = 56/99 (56%), Gaps = 5/99 (5%)
 Frame = +1

Query: 213 ALNHLKENLKIIHRDIKPSNILLDRSGNIKLCDFGISGQLV-DSIAKTRDAGCR---PYM 268
            + +L+E +K++HR++   N ++   G ++L D+G++G L   S     D+  R    +M
Sbjct: 85  GMAYLQE-VKVVHRNLAARNCIVTEDGRLQLSDYGVTGSLFPQSYYTADDSPARDLVKWM 261

Query: 269 APERIDPSASRQGYDVRSDVWSLGITLYELAT-GRFPYP 306
           APE ID       +  +SDVW+ G+ L+EL T G  PYP
Sbjct: 262 APETID----NFHFSSKSDVWAFGVVLWELLTRGITPYP 366
>03240
          Length = 1683

 Score = 59.3 bits (142), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 59/259 (22%), Positives = 102/259 (39%), Gaps = 59/259 (22%)
 Frame = -3

Query: 106  IGRGAYGSVNKMVHKPSGQIMAVKRIR-STVDEKEQKQLLMDLDVVMRSSDCPYIVQFYG 164
            +G GA+G V+      +G + A+K +R S V ++ Q   +     ++  +D  ++V+ Y 
Sbjct: 1267 LGVGAFGEVSLCRKNDTGMLYAMKTLRKSDVLKRNQVAHVKAERDILAEADNEWVVKLYY 1088

Query: 165  ALFREGDCWICMELMSTSFDKFYKYVYSVLDDV-------------IPEEILGKITLATV 211
            +                   + + Y+Y V+D V             I +E L +  +A +
Sbjct: 1087 SF------------------QDHNYLYFVMDYVPGGDLMGLLIRMEILDEPLARFYVAEL 962

Query: 212  KALNHLKENLKIIHRDIKPSNILLDRSGNIKLCDFGISG--------------------- 250
                     +  IHRDIKP NIL+DR+G+IKL DFG+                       
Sbjct: 961  VQAIESVHRMGFIHRDIKPDNILIDRNGHIKLTDFGLCTGFRWTHNSKYYQRDGTHARQD 782

Query: 251  --------------QLVDSIAKTRD----------AGCRPYMAPERIDPSASRQGYDVRS 286
                          +++  + + R            G   Y+APE +   +   GY    
Sbjct: 781  SMEVKCQLDEQCQCEILKPLERRRKREQRCLAHSLVGTPNYIAPEVL---SRLGGYTSVC 611

Query: 287  DVWSLGITLYELATGRFPY 305
            D WS+G+ L+E+  G  P+
Sbjct: 610  DWWSVGVILFEMLVGHPPF 554
>14116
          Length = 1017

 Score = 57.8 bits (138), Expect = 8e-09,   Method: Compositional matrix adjust.
 Identities = 53/208 (25%), Positives = 97/208 (46%), Gaps = 12/208 (5%)
 Frame = -1

Query: 105 EIGRGAYGSVNK---MVHKPSGQIM-AVKRIRSTVDEKEQKQLLMDLDVVMRSSDCPYIV 160
           EIG+G +G V +    + +  G I+ AVK + +    + + Q  +   ++M+      ++
Sbjct: 615 EIGKGNFGCVKRGFLTLPEQKGDILVAVKTLHNNNPREIELQSFLQEALIMKDFHHSNVL 436

Query: 161 QFYGALFREGDCWICMELMSTSFDKFYKYVYSVLDD----VIPEEILGKITLATVKALNH 216
              G      D    M L+   F K    +  + DD     I + I+  + +A  + +++
Sbjct: 435 TLIGICLNLDD----MPLVVLPFMKHGDLLTYIRDDQHQPTIKDLIMYGVDIA--RGMDY 274

Query: 217 LKENLKIIHRDIKPSNILLDRSGNIKLCDFGISGQLVD----SIAKTRDAGCRPYMAPER 272
           L   LK +HRD+   N +LD   ++K+ DFG++  + +    S    +      +MA E 
Sbjct: 273 LA-GLKFVHRDLAARNCMLDEDFHVKVADFGLARDIYEKEYYSSENKKAKLPVKWMALE- 100

Query: 273 IDPSASRQGYDVRSDVWSLGITLYELAT 300
              S  +  YD ++DVWS G+ L+EL T
Sbjct: 99  ---SLEKGNYDSKTDVWSYGVVLWELLT 25
>18484
          Length = 635

 Score = 57.8 bits (138), Expect = 8e-09,   Method: Compositional matrix adjust.
 Identities = 31/84 (36%), Positives = 48/84 (57%), Gaps = 1/84 (1%)
 Frame = +1

Query: 223 IIHRDIKPSNILLDRSGNIKLCDFGISGQLVDSIAKTRD-AGCRPYMAPERIDPSASRQG 281
           II+RD+K  N++LD  G+IK+ DFG+  + +   A TR   G   Y+APE +      Q 
Sbjct: 106 IIYRDLKLDNVMLDSEGHIKIADFGMCKEGMTGDATTRTFCGTPDYIAPEIV----LYQP 273

Query: 282 YDVRSDVWSLGITLYELATGRFPY 305
           Y    D W+ G+ L+E+  G+ P+
Sbjct: 274 YSKSVDWWAYGVLLFEMLAGQPPF 345
>19301
          Length = 712

 Score = 56.6 bits (135), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 48/173 (27%), Positives = 81/173 (46%), Gaps = 2/173 (1%)
 Frame = +2

Query: 79  IESSGKLKISPEQHWDFTAEDLKDLGEIGRGAYGSVNKMVHKPSGQIMAVKRIRSTVDEK 138
           I  +   ++  +  W+   E + DL  +G GA G+V   + K   + +AVK++R  + E 
Sbjct: 248 IGKAAAAELKQQDDWEIPFESITDLEWLGSGAQGAV--FLGKLCAEEVAVKKVRD-IKET 418

Query: 139 EQKQLLMDLDVVMRSSDCPYIVQFYGALFREGDCWICMELMSTSFDKFYKYVYSVLDD-- 196
           + + L        R  + P I+ F G   +     I ME         Y  +Y VL D  
Sbjct: 419 DIRNL--------RKLNHPNIISFKGVCTQAPCYCIIMEYCP------YGQLYEVLRDGK 556

Query: 197 VIPEEILGKITLATVKALNHLKENLKIIHRDIKPSNILLDRSGNIKLCDFGIS 249
            IP  ++   +      +N+L  + KIIHRD+K  N+L+ ++  +K+ DFG S
Sbjct: 557 EIPPALVLDWSKQIASGMNYLHSH-KIIHRDLKSPNVLVAKNDVVKISDFGTS 712
>15910
          Length = 1361

 Score = 56.2 bits (134), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 41/146 (28%), Positives = 67/146 (45%), Gaps = 3/146 (2%)
 Frame = +2

Query: 223 IIHRDIKPSNIL---LDRSGNIKLCDFGISGQLVDSIAKTRDAGCRPYMAPERIDPSASR 279
           ++HRD+KP N+L   +     +KL DFG+S  +   +  +   G   Y APE +      
Sbjct: 527 VVHRDLKPENLLYECMTDDSKLKLADFGLSRIIEPEVQMSTVCGTPGYCAPEVL----KG 694

Query: 280 QGYDVRSDVWSLGITLYELATGRFPYPKWNSVFDQLTQVVKGDPPQLSNSEEREFSPSFI 339
             Y    D+WS+G+  Y L  G  P+   N  F+   +++KG+  +       E S +  
Sbjct: 695 DKYTPSVDMWSVGVIAYILLCGYEPFFAENE-FEMYRKIIKGE-YKFDEEYWSEISENAK 868

Query: 340 NFVNLCLTKDESKRPKYKELLKHPFI 365
           + V   L  D  KR    E L+ P++
Sbjct: 869 DVVRKLLVIDPKKRLTATEALRLPWV 946
>01756
          Length = 1858

 Score = 55.1 bits (131), Expect = 4e-08,   Method: Compositional matrix adjust.
 Identities = 65/251 (25%), Positives = 107/251 (42%), Gaps = 25/251 (9%)
 Frame = -3

Query: 95   FTAEDLK--DLGEIGRGAYGSVNKMVHKPSGQIMAVKRIR----------STVDEKEQKQ 142
            F  ED K   L +IG+G +G V K   K + Q++A+K++           + + E +  Q
Sbjct: 1757 FCDEDAKYEKLAKIGQGTFGEVFKARCKKTKQVVAMKKVLMDNEKEGFPITALREIKILQ 1578

Query: 143  LLMDLDVVMRSSDCP--------YIVQFYGAL-FREGDCWICMELMSTSFDKFYKYVYSV 193
            LL   +VV     C         Y   FY    F E D    +  MS  F+         
Sbjct: 1577 LLNHENVVDLIEICSTKATSANRYKSMFYLVFEFCEHDLAGLLSNMSVVFN--------- 1425

Query: 194  LDDVIPEEILGKITLATVKALNHLKENLKIIHRDIKPSNILLDRSGNIKLCDFGISGQLV 253
                +PE  + ++    +  L ++  N KI+HRD+K +NIL+ + G +KL DFG++    
Sbjct: 1424 ----LPE--IKEVMKQLMNGLYYIHRN-KILHRDMKAANILITKQGVLKLADFGLARAFS 1266

Query: 254  DSIAKTRDAGCRP----YMAPERIDPSASRQGYDVRSDVWSLGITLYELATGRFPYPKWN 309
             ++ +      R     Y  PE +      + Y    D W  G  + E+ T R P  +  
Sbjct: 1265 VNLRQPNRYTNRVVTLWYRPPELL---LGDRNYSTAIDQWGAGCIMAEMWT-RNPIMQGT 1098

Query: 310  SVFDQLTQVVK 320
            +  +QLT + +
Sbjct: 1097 TEQNQLTLITQ 1065
>00392
          Length = 668

 Score = 53.1 bits (126), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 31/104 (29%), Positives = 56/104 (53%), Gaps = 1/104 (0%)
 Frame = +3

Query: 223 IIHRDIKPSNILLDR-SGNIKLCDFGISGQLVDSIAKTRDAGCRPYMAPERIDPSASRQG 281
           +IHRD+K  NI +   +G++K+ D G++     S AK+   G   +MAPE  +     + 
Sbjct: 315 VIHRDLKCDNIFITGPTGSVKIGDLGLATLKNQSFAKSV-IGTPEFMAPEMYE-----EH 476

Query: 282 YDVRSDVWSLGITLYELATGRFPYPKWNSVFDQLTQVVKGDPPQ 325
           YD   DV++ G+ + E+A+  +PY + ++      +V  G  P+
Sbjct: 477 YDEAVDVYAFGMCMLEMASSEYPYSECSNAAQIYKRVTSGVLPE 608
>11780
          Length = 1713

 Score = 52.0 bits (123), Expect = 4e-07,   Method: Compositional matrix adjust.
 Identities = 43/158 (27%), Positives = 80/158 (50%), Gaps = 1/158 (0%)
 Frame = +3

Query: 93  WDFTAEDLKDLGE-IGRGAYGSVNKMVHKPSGQIMAVKRIRSTVDEKEQKQLLMDLDVVM 151
           W    +DL ++GE IG+G +G V K +++  GQ +A+K+++   D+   +Q  +    VM
Sbjct: 582 WVIAXQDL-EIGEAIGKGDFGDVYKGMYR--GQPVAIKQLK---DKDRGEQSFLQEASVM 743

Query: 152 RSSDCPYIVQFYGALFREGDCWICMELMSTSFDKFYKYVYSVLDDVIPEEILGKITLATV 211
            S     +V+  G +  E   ++  E M        +Y+ S    VI ++        T 
Sbjct: 744 TSLRHDNLVRLIGVVLGE-TIFLVTEFMGKG--NLVEYLRSRGRSVITKKDQINFATDTC 914

Query: 212 KALNHLKENLKIIHRDIKPSNILLDRSGNIKLCDFGIS 249
            A+ +L E+ +++HRD+   N+L+   G  K+ DFG++
Sbjct: 915 AAMEYL-ESKRLVHRDLAARNVLVHDDGKAKVSDFGLA 1025
>26711
          Length = 405

 Score = 52.0 bits (123), Expect = 5e-07,   Method: Compositional matrix adjust.
 Identities = 27/85 (31%), Positives = 48/85 (56%), Gaps = 2/85 (2%)
 Frame = -2

Query: 223 IIHRDIKPSNILL--DRSGNIKLCDFGISGQLVDSIAKTRDAGCRPYMAPERIDPSASRQ 280
           ++H D+KPSN+LL  D+  +++L DFG++ +L        + G   + +PE +D     +
Sbjct: 353 VVHMDLKPSNLLLSGDKLDSVQLIDFGLARKLYPPQETFLNHGTPGFTSPEALD----VK 186

Query: 281 GYDVRSDVWSLGITLYELATGRFPY 305
                SDVW +G+  Y L +G+ P+
Sbjct: 185 PISTASDVWGVGVLAYILLSGQSPF 111
>28638
          Length = 1458

 Score = 51.2 bits (121), Expect = 7e-07,   Method: Compositional matrix adjust.
 Identities = 35/86 (40%), Positives = 46/86 (53%), Gaps = 2/86 (2%)
 Frame = -1

Query: 221 LKIIHRDIKPSNILL--DRSGNIKLCDFGISGQLVDSIAKTRDAGCRPYMAPERIDPSAS 278
           + IIH D+KP NILL   +   IK+ DFG S QL   I +   +  R Y +PE +     
Sbjct: 774 MNIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQS--RFYRSPEVLLGVP- 604

Query: 279 RQGYDVRSDVWSLGITLYELATGRFP 304
              YD+  D+WSLG  L E+ TG  P
Sbjct: 603 ---YDLAIDMWSLGCILVEMHTGEPP 535
>07940
          Length = 1336

 Score = 51.2 bits (121), Expect = 8e-07,   Method: Compositional matrix adjust.
 Identities = 35/90 (38%), Positives = 50/90 (55%), Gaps = 5/90 (5%)
 Frame = -3

Query: 222 KIIHRDIKPSNILLDRSGNIKLCDFGISGQL--VDSIAKTRDAGCRP--YMAPERIDPSA 277
           + IHRD+   N+L+     +K+ DFG++  L   D   KT D G  P  +MAPE +    
Sbjct: 287 QCIHRDLAARNVLVAEEYVLKIADFGLTRNLQQFDYYRKTTD-GRLPVKWMAPEAL---- 123

Query: 278 SRQGYDVRSDVWSLGITLYELAT-GRFPYP 306
             + Y  +SDVWS G+ L+E+ T G  PYP
Sbjct: 122 FDRKYTSKSDVWSYGVLLWEIFTLGGNPYP 33

 Score = 29.3 bits (64), Expect = 2.9,   Method: Compositional matrix adjust.
 Identities = 20/94 (21%), Positives = 43/94 (45%), Gaps = 5/94 (5%)
 Frame = -3

Query: 90  EQHWDFTAEDLKDLGEIGRGAYGSVNK----MVHKPSGQI-MAVKRIRSTVDEKEQKQLL 144
           +  W+F  E L     +G GA+G V K     + K +  + +AVK ++    ++E   L+
Sbjct: 866 DAKWEFPRERLVLGDRLGEGAFGLVMKGEAMGIFKDNNSVTVAVKMLKEDATDREMMDLI 687

Query: 145 MDLDVVMRSSDCPYIVQFYGALFREGDCWICMEL 178
            +++++        I+   G   + G  ++ +E 
Sbjct: 686 REMEMMKVIGKHKNIINLLGCCTQRGALYVIVEF 585
>16708
          Length = 1397

 Score = 50.4 bits (119), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 34/100 (34%), Positives = 53/100 (53%), Gaps = 12/100 (12%)
 Frame = -1

Query: 211  VKALNHLKENLKIIHRDIKPSNILLDRSGNIKLCDFGISG--QLVDSIAKTRDAGC---- 264
            V AL H+ E L ++H D+K  N+L+D  GN KL D+GI+   ++  +  +T  +GC    
Sbjct: 1064 VCALEHIHE-LGVVHMDVKADNVLVDAHGNCKLTDYGIAQLYKVYPAPTETHSSGCTNKR 888

Query: 265  ----RPYMAPERIDPSA--SRQGYDVRSDVWSLGITLYEL 298
                RP   P  + PS   S +G  + +D + LG  L+ L
Sbjct: 887  TFYTRP---PATMTPSERFSEEGDGIGTDYFRLGQMLWTL 777
>04591
          Length = 1117

 Score = 50.1 bits (118), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 29/77 (37%), Positives = 40/77 (51%)
 Frame = -2

Query: 222 KIIHRDIKPSNILLDRSGNIKLCDFGISGQLVDSIAKTRDAGCRPYMAPERIDPSASRQG 281
           +I+HRDIK +NILL R G +KL DFG+S   V S   T       Y  PE +      + 
Sbjct: 837 QILHRDIKAANILLTRDGVLKLADFGLSRPWVKSKRLTNRVVTLWYRPPELL---LGERE 667

Query: 282 YDVRSDVWSLGITLYEL 298
           Y    D+W +G  + E+
Sbjct: 666 YGPEIDMWGVGCIMAEM 616
>01966
          Length = 1735

 Score = 50.1 bits (118), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 39/158 (24%), Positives = 71/158 (44%), Gaps = 5/158 (3%)
 Frame = -1

Query: 119  HKPSGQIMAVKRIRSTVDEKEQKQLLMDLDVVMRSSDCPYIVQFYGALFREGDCWICMEL 178
            H+ +G+ +A+K+IR    E       +    ++R      IV     +  +   ++  E 
Sbjct: 1648 HRATGRKLAMKKIRLRGSEDGVPSSAIREIAMLRELRHTNIVCLEDVIMEDERLFLVFEF 1469

Query: 179  MSTSF----DKFYKYVYSVLDDVIPEEILGKITLATVKALNHLKENLKIIHRDIKPSNIL 234
            +S       DKF + V      V+   ++       V  +N   +  +I+HRD+KP N+L
Sbjct: 1468 LSMDLKMYIDKFPEGV------VLDRRLVKSYVFQIVTGINFCHQR-RIVHRDLKPQNLL 1310

Query: 235  LDRSGNIKLCDFGISGQLVDSI-AKTRDAGCRPYMAPE 271
            ++ +G IK+ DFG++      + A T +     Y APE
Sbjct: 1309 INHTGAIKIADFGMARTFALPVRAYTHEVVTLWYRAPE 1196
>07836
          Length = 1478

 Score = 49.7 bits (117), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 42/191 (21%), Positives = 90/191 (47%), Gaps = 14/191 (7%)
 Frame = -1

Query: 123  GQIMAVKRIRSTVDEKEQKQLLMDLDVVMRSSDCPYIVQFYGALFREGDCWICMELMSTS 182
            G+ +AVK   +T +    ++  +   V++R  +   I+ F  A  +    W  + L++  
Sbjct: 1478 GENVAVKIFFTTEEASWFRETELYQTVLLRHEN---ILGFIAADIKGTGSWTQLFLITDY 1308

Query: 183  FDKFYKYVYSVLDDVIPEEILGKITLATVKALNHLKENL-------KIIHRDIKPSNILL 235
             +    + Y +L  V+    +  +  + +  L HL   +        I HRDIK  NIL+
Sbjct: 1307 HENGSLHDY-LLSRVLDSSEMLALAHSAICGLAHLHIEIFGTRGKPAIAHRDIKSKNILV 1131

Query: 236  DRSGNIKLCDFGISGQLVDS-----IAKTRDAGCRPYMAPERIDPSASRQGYDV--RSDV 288
             ++G   + D G++ + +       +A     G + YMAPE ++   + + +D   ++D+
Sbjct: 1130 KKNGTCCIADLGLAVRYISESNEVDVAPNPRQGTKRYMAPEVLEMLLNVKNFDAFKQADM 951

Query: 289  WSLGITLYELA 299
            ++ G+ ++E+A
Sbjct: 950  YAFGLVMWEIA 918
>17300
          Length = 480

 Score = 48.5 bits (114), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 36/108 (33%), Positives = 57/108 (52%), Gaps = 6/108 (5%)
 Frame = +1

Query: 220 NLKIIHRDIKPSNILLDRSGNIKLCDFGISGQLVDSI---AKTRDAGCRP--YMAPERID 274
           ++  +HRD+   NIL++     K+ DFG+S ++       A T   G  P  + APE I 
Sbjct: 28  DMGYVHRDLAARNILVNEILVCKVADFGLSREIESDTTEGAYTTKGGKIPVRWTAPEAI- 204

Query: 275 PSASRQGYDVRSDVWSLGITLYE-LATGRFPYPKWNSVFDQLTQVVKG 321
             A R+ +   SDVWS G+ ++E ++ G  PY  W++  D +  V KG
Sbjct: 205 --AYRK-FTSASDVWSFGVVMWEVMSYGERPYWNWSNQ-DVIKAVEKG 336
>21433
          Length = 590

 Score = 48.1 bits (113), Expect = 7e-06,   Method: Compositional matrix adjust.
 Identities = 33/83 (39%), Positives = 46/83 (55%)
 Frame = +2

Query: 222 KIIHRDIKPSNILLDRSGNIKLCDFGISGQLVDSIAKTRDAGCRPYMAPERIDPSASRQG 281
           K+IHRDIKP N+LL   G++K+ DFG S     S  +T   G   Y+ PE ++     + 
Sbjct: 227 KVIHRDIKPENLLLGLKGDLKIADFGWSVH-APSSRRTTMCGTLDYLPPEMVE----GKT 391

Query: 282 YDVRSDVWSLGITLYELATGRFP 304
           +D   D+WSLG+  YE   G  P
Sbjct: 392 HDENVDLWSLGVLCYEFLVGTPP 460
>17253
          Length = 483

 Score = 47.8 bits (112), Expect = 8e-06,   Method: Compositional matrix adjust.
 Identities = 35/146 (23%), Positives = 62/146 (42%), Gaps = 9/146 (6%)
 Frame = -1

Query: 118 VHKPSGQIMAVKRIRSTVDEKEQKQLLMDLDVVMRSSDCPYIVQFYGALFREGDCWICME 177
           VH      +AVK       + E+ + L +L ++ +    P +V F G         I ME
Sbjct: 483 VHARQWDTVAVKTHNEAATDAEKSEFLRELSIMRKLPRHPNVVSFMGCCTMSDPALILME 304

Query: 178 LMS----TSFDKFYK-----YVYSVLDDVIPEEILGKITLATVKALNHLKENLKIIHRDI 228
                   SF +  +     ++ S  +D+   +      L   + + H+  N KI+HRD+
Sbjct: 303 FCCHGDLLSFLRKRRPDRTVFLTSTANDLTARDFFS-FALHVARGMAHVANN-KIVHRDV 130

Query: 229 KPSNILLDRSGNIKLCDFGISGQLVD 254
              N+L+      K+ DFG+S ++ D
Sbjct: 129 AARNVLISERNVCKVSDFGLSRRVGD 52
>12672
          Length = 773

 Score = 47.4 bits (111), Expect = 9e-06,   Method: Compositional matrix adjust.
 Identities = 35/104 (33%), Positives = 49/104 (47%), Gaps = 7/104 (6%)
 Frame = +3

Query: 205 KITLATVKALNHLKENLKIIHRDIKPSNILLDRSGNIKLCDFGI-----SGQLVDSIAKT 259
           KI   T   + +L +N  + HRDIK +NILLD     K+ DF       SG+       +
Sbjct: 3   KIVKGTASGIQYLNDNGHV-HRDIKTANILLDSEYTAKVGDFATVVSAPSGEGKTVQNAS 179

Query: 260 RDAGCRPYMAPERIDPSASRQGYDVRS--DVWSLGITLYELATG 301
              G   Y+APE I        +DV +  D +S G+ L E+ TG
Sbjct: 180 VVIGTAAYLAPEAIH-------FDVSTKLDSYSFGVVLLEVITG 290
>28157
          Length = 400

 Score = 46.6 bits (109), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 45/134 (33%), Positives = 66/134 (49%), Gaps = 10/134 (7%)
 Frame = +3

Query: 126 MAVKRIRSTVDEKEQKQLLMDLDVVMRSSDCPYIVQFYGALFREGDCWICMELMSTSFDK 185
           +AVKRI S   E+E+K  + +L  + R S  P IV  YGA      C + ME        
Sbjct: 9   VAVKRIES---EQEKKSFMQELKQLSRVSH-PNIVCLYGACRDHPVCLV-MEYAEGG--- 164

Query: 186 FYKYVYSVLDDVIPE---------EILGKITLATVKALNHLKENLKIIHRDIKPSNILLD 236
               +Y+VL    P+           L +  L  V+ L+ +K    +IHRD+KP N+LL 
Sbjct: 165 ---SLYNVLHGSGPQPQYTAAHAMNWLLQCALG-VEYLHGMKPK-ALIHRDLKPPNLLLI 329

Query: 237 RSGN-IKLCDFGIS 249
           + G  +K+CDFG +
Sbjct: 330 QCGTKLKICDFGTA 371
>13066
          Length = 551

 Score = 46.2 bits (108), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 44/153 (28%), Positives = 65/153 (42%), Gaps = 6/153 (3%)
 Frame = +3

Query: 146 DLDVVMRSSDCPYIVQFYGALFREGDCWICMELMSTSFDKFYKYVYSVLDDVIPEEILGK 205
           +LD++ +  D PYI+Q +  L R    +I M            Y+  V    + E+    
Sbjct: 126 ELDLLTKL-DHPYIIQIHSILQRXPKNFIFMRFAERG--DLLTYIQEV--GFVKEKQAKI 290

Query: 206 ITLATVKALNHLKENLKIIHRDIKPSNILLDRSGNIKLCDFGISGQLV----DSIAKTRD 261
                  ALN+L  +  + HRD+K  NILL    N+KL DFG +   +    +       
Sbjct: 291 WFYQMTTALNYL-HSYDVAHRDLKCENILLSSHFNVKLADFGFACACITESGEKYMSRTY 467

Query: 262 AGCRPYMAPERI--DPSASRQGYDVRSDVWSLG 292
            G   Y APE +   P A +      +D WSLG
Sbjct: 468 CGSAAYAAPEIVYGAPYAPKV-----ADAWSLG 551
>04138
          Length = 800

 Score = 46.2 bits (108), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 43/165 (26%), Positives = 70/165 (42%), Gaps = 11/165 (6%)
 Frame = +1

Query: 222 KIIHRDIKPSNILLDRSGNIKLCDFGISGQLVDSIAK----TRDAGCRPYMAPERIDPSA 277
           KI+HRD+K +NIL+ + G +KL DFG++     ++ +    T       Y  PE +    
Sbjct: 73  KILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRVVTLWYRPPELL---L 243

Query: 278 SRQGYDVRSDVWSLGITLYELATGRFPYPKWNSVFDQLTQVVKGDPPQLSNSEEREFSPS 337
             + Y    D W  G  + E+ T R P  +  +  +QLT +      QL  S   E  P 
Sbjct: 244 GDRNYSTAIDQWGAGCIMAEMWT-RNPIMQGTTEQNQLTLIT-----QLCGSITPEVWPG 405

Query: 338 FINFV-------NLCLTKDESKRPKYKELLKHPFILMYEERTVEV 375
                        L   +    R ++  +LK P+ L   ER +++
Sbjct: 406 VTQLSMYHQIKGALAAGRKNIIRDRFARILKDPYGLDLFERLLKM 540
>29581
          Length = 1278

 Score = 45.8 bits (107), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 37/111 (33%), Positives = 54/111 (48%), Gaps = 4/111 (3%)
 Frame = -2

Query: 192  SVLDDV---IPEEILGKITLATVKALNHLKENLKIIHRDIKPSNILLDRSGNIKLCDFGI 248
            S+LD++     E  +  I L  +K L +L E   IIHRD+K SN+L+   G +K+ DFG+
Sbjct: 1085 SLLDNMPAPFSESQVKCIVLQLLKGLRYLHEAF-IIHRDLKVSNLLMTDKGCVKIADFGL 909

Query: 249  SGQLVD-SIAKTRDAGCRPYMAPERIDPSASRQGYDVRSDVWSLGITLYEL 298
            +          T       Y APE +  S +   +    D+WS G  L EL
Sbjct: 908  ARNYGKPQKPMTPKVVTLWYRAPELLFGSKT---HSTAIDMWSAGCILGEL 765
>27405
          Length = 532

 Score = 45.8 bits (107), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 28/79 (35%), Positives = 43/79 (54%), Gaps = 2/79 (2%)
 Frame = -3

Query: 213 ALNHLKENLKIIHRDIKPSNILLDRSGNIKLCDFGISGQLVDSIAKTRDA--GCRPYMAP 270
            L H+     +++RD+KP+NILLD +G++++ D G++    D   K   A  G   YMAP
Sbjct: 218 GLEHMHSRF-VVYRDLKPANILLDENGHVRISDLGLA---CDFSKKKPHASVGTHGYMAP 51

Query: 271 ERIDPSASRQGYDVRSDVW 289
           E +      Q YD  +D W
Sbjct: 50  EVL---MKGQAYDSSAD-W 6
>18996
          Length = 491

 Score = 45.1 bits (105), Expect = 6e-05,   Method: Compositional matrix adjust.
 Identities = 32/87 (36%), Positives = 48/87 (55%), Gaps = 6/87 (6%)
 Frame = +2

Query: 224 IHRDIKPSNILLDRSGNIKLCDFGISGQLVDSIA-----KTRDAGCRPYMAPERIDPSAS 278
           IHRD+   NIL+DRS  +K+ DFG++ Q  ++         RD   + Y +PE I+    
Sbjct: 2   IHRDLAARNILVDRSC-VKISDFGLA-QFANADGYYYGISQRDIPIKWY-SPEAIETCK- 169

Query: 279 RQGYDVRSDVWSLGITLYEL-ATGRFP 304
              +   SDVWS G+TL+E+ + G  P
Sbjct: 170 ---FSSYSDVWSYGVTLFEMFSRGEIP 241
>21079
          Length = 878

 Score = 44.3 bits (103), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 28/86 (32%), Positives = 43/86 (50%), Gaps = 3/86 (3%)
 Frame = +1

Query: 222 KIIHRDIKPSNILL--DRSGNIKLCDFGISGQLVDSIAKTRDAGCRPYMAPERIDPS-AS 278
            I+H D+KP N+L   D S  IK+ DFG++        K  D+    +  PE I P   +
Sbjct: 187 SILHLDLKPENVLCVSDNSNQIKIIDFGLA-----RFYKPGDSLQVLFGTPEFIAPEVVN 351

Query: 279 RQGYDVRSDVWSLGITLYELATGRFP 304
               +  +D+WS+G+  Y L +G  P
Sbjct: 352 YDEINFTTDMWSIGVICYILLSGLSP 429
>17975
          Length = 449

 Score = 43.9 bits (102), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 36/141 (25%), Positives = 72/141 (51%), Gaps = 2/141 (1%)
 Frame = +3

Query: 119 HKPSGQIMAVKRI-RSTVDEKEQKQLLMDLDVVMRSSDCPYIVQFYGALFREGDCWICME 177
           H  +G+ +AVK I ++ +DE  +  L  ++   M+    P +V+ Y  +  +   ++ +E
Sbjct: 30  HVFTGEKVAVKVIDKTKLDEVSRSHLFQEVRC-MKLVQHPNVVRLYEVIDTQTKLYLILE 206

Query: 178 LMSTSFDKFYKYVYSVLDDVIPEEILGKITLATVKALNHLKENLKIIHRDIKPSNIL-LD 236
           L        Y Y+       + E++  +     V+A+++    L ++HRD+KP N++  +
Sbjct: 207 LGDGG--DMYDYIMR-HSGGLEEKLAKRYFRQIVEAISYC-HKLHVVHRDLKPENVVFFE 374

Query: 237 RSGNIKLCDFGISGQLVDSIA 257
           + G +KL DFG S  L+ + A
Sbjct: 375 KPGLVKLTDFGFSTCLLQAKA 437
>37063
          Length = 455

 Score = 43.5 bits (101), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 31/86 (36%), Positives = 40/86 (46%), Gaps = 10/86 (11%)
 Frame = -2

Query: 228 IKPSNIL---LDRSGNIKLCDFGISGQLVDSIAKTRD------AGCRPYMAPERIDPSAS 278
           +KP NIL   LD    +K+CDF ++  +      T+        G   YMAPE +D    
Sbjct: 454 LKPENILCEHLDEVVPLKICDFDLASGINCDGDGTKTPELLTPVGSAEYMAPEVVDAWVG 275

Query: 279 RQ-GYDVRSDVWSLGITLYELATGRF 303
               YD R D+WSLGI L  L    F
Sbjct: 274 ESFSYDKRCDMWSLGIIL*VLVMCAF 197
>03508
          Length = 1463

 Score = 43.1 bits (100), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 25/83 (30%), Positives = 43/83 (51%), Gaps = 1/83 (1%)
 Frame = +1

Query: 211 VKALNHLKENLKIIHRDIKPSNILLDRSG-NIKLCDFGISGQLVDSIAKTRDAGCRPYMA 269
           +KAL+    ++ I+HRD+KP N+++D     ++L D+G++      +        R +  
Sbjct: 901 MKALD-FCHSMGIMHRDVKPHNVMIDHENKKLRLIDWGLAEFYHPGMEYNVRVASRYFKG 1077

Query: 270 PERIDPSASRQGYDVRSDVWSLG 292
           PE +      Q YD   D+WSLG
Sbjct: 1078PELL---LDYQMYDYSLDMWSLG 1137
>25019
          Length = 730

 Score = 42.7 bits (99), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 24/62 (38%), Positives = 34/62 (54%), Gaps = 1/62 (1%)
 Frame = +3

Query: 232 NILLDRSGNIKLCDFGISGQLVDSIAKTRD-AGCRPYMAPERIDPSASRQGYDVRSDVWS 290
           N+LLD+ G++KL DFG+  + +     T    G   YMAPE +    +R G+    D WS
Sbjct: 264 NVLLDKDGHVKLTDFGLCKEAITGTRVTHTFCGTIEYMAPEIL----TRTGHGKAVDWWS 431

Query: 291 LG 292
           LG
Sbjct: 432 LG 437
>37602
          Length = 804

 Score = 41.6 bits (96), Expect = 6e-04,   Method: Compositional matrix adjust.
 Identities = 28/88 (31%), Positives = 43/88 (48%)
 Frame = -1

Query: 159 IVQFYGALFREGDCWICMELMSTSFDKFYKYVYSVLDDVIPEEILGKITLATVKALNHLK 218
            V ++ +  R    WI ME          + +Y V   +   +I   +   T+K L++L 
Sbjct: 333 FVGYFDSYLRREKLWIAMEYCGGGS---MQDIYHVTGPLTEPQI-AFVCRETLKGLHYLH 166

Query: 219 ENLKIIHRDIKPSNILLDRSGNIKLCDF 246
              K+ HRDIK +NILL   G++KL DF
Sbjct: 165 RRGKM-HRDIKGANILLTEEGDVKLADF 85
>20640
          Length = 1492

 Score = 40.4 bits (93), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 35/140 (25%), Positives = 61/140 (43%), Gaps = 2/140 (1%)
 Frame = +1

Query: 224 IHRDIKPSNILLDRSGNIKLCDFGISGQLVDSIAKTRDAGCRPYMAPERIDPSAS--RQG 281
           +HRD+   N L+     +K+ DFG++ + V S+   R  G      P R  P  +     
Sbjct: 10  VHRDLATRNCLVGHDLVVKISDFGLA-RSVHSVDYYR--GSEHDAIPIRWMPLEAILYNK 180

Query: 282 YDVRSDVWSLGITLYELATGRFPYPKWNSVFDQLTQVVKGDPPQLSNSEEREFSPSFINF 341
           +  +SDVWS G+ L+E+       P +    +++ + VK    ++    ER   P     
Sbjct: 181 FSTQSDVWSFGVVLWEIFAFALQ-PYYGLTHEEVVRFVKEG--KVLACPERT-PPPMYEL 348

Query: 342 VNLCLTKDESKRPKYKELLK 361
           +  C  +  + RP +  L K
Sbjct: 349 MKQCWHRRPATRPSFHTLHK 408
>08294
          Length = 1849

 Score = 38.5 bits (88), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 37/161 (22%), Positives = 74/161 (45%), Gaps = 4/161 (2%)
 Frame = +2

Query: 203  LGKITLATVKALNHLKENLKIIHRDIKPSNILLDRSGNIKLCDFGISGQLVDSIAKTRDA 262
            +G+   A ++AL+    N  ++H D+   N+LL     +K+    +SG +  S       
Sbjct: 1058 MGQQVAAGMEALS----NQGLVHGDLAARNVLLTSRMQLKVARPALSGDVYASEYYPLHQ 1225

Query: 263  GCRP--YMAPERI-DPSASRQGYDVRSDVWSLGITLYE-LATGRFPYPKWNSVFDQLTQV 318
               P  ++ PE + + SA+  G     DVW+ G+ L+E L     PY     + D+  +V
Sbjct: 1226 RLVPLRWLPPEGVLEDSATTCG-----DVWAFGVFLWEVLQLADLPY---RLMSDE--EV 1375

Query: 319  VKGDPPQLSNSEEREFSPSFINFVNLCLTKDESKRPKYKEL 359
            ++      +  +  +  P+ ++ +  C  +  S+RP + E+
Sbjct: 1376 LRSLQHSQAALDSPDAPPALLSLLQRCTAQQPSQRPPFSEI 1498
>07833
          Length = 1504

 Score = 37.4 bits (85), Expect = 0.011,   Method: Compositional matrix adjust.
 Identities = 30/119 (25%), Positives = 56/119 (47%), Gaps = 16/119 (13%)
 Frame = -3

Query: 267  YMAPERIDPSASRQGYDVRS---DVWSLGITLYELATGRFPYPKWNSVFDQLTQVVKG-- 321
            +MAPE +     R+  D+ +   D+WS  I ++EL T   P+ + +S+   +   ++G  
Sbjct: 1124 WMAPEALQ----RRPDDINTRAADMWSFAILMWELETREVPFAELSSMEVGMKVALEGLR 957

Query: 322  --DPPQLSNSEEREFSPSFINFVNLCLTKDESKRPKYK------ELLKH---PFILMYE 369
               PP +S    R         + +C+ ++  KRP++       E +KH   P  L+Y+
Sbjct: 956  ISIPPGISLHMSR--------LIKICMNEEPGKRPRFDMIIPILEKMKHQ*TPSTLLYQ 804
>00486
          Length = 797

 Score = 37.0 bits (84), Expect = 0.013,   Method: Compositional matrix adjust.
 Identities = 24/69 (34%), Positives = 36/69 (52%), Gaps = 3/69 (4%)
 Frame = -2

Query: 263 GCRPYMAPERIDPSASRQGYDVRSDVWSLGITLYELATGRFPYPKWNSVFDQLTQVVKGD 322
           G   YMAPE +    +R G+    D WSLG  +Y++ TG  P+   N     + +++KG 
Sbjct: 772 GTIEYMAPEIL----TRTGHGKAVDWWSLGALMYDMLTGSPPFTAENRK-KTIDKILKGK 608

Query: 323 ---PPQLSN 328
              PP L+N
Sbjct: 607 LNLPPYLTN 581
>11404
          Length = 563

 Score = 36.6 bits (83), Expect = 0.016,   Method: Compositional matrix adjust.
 Identities = 44/158 (27%), Positives = 70/158 (44%), Gaps = 9/158 (5%)
 Frame = +1

Query: 87  ISPEQHWDFTAEDLKDLGEIGRGAYGSVNKMVHKPSGQIMAVKRIRSTVDEKEQKQLLMD 146
           ISP + W   A+  +    IG+G++G V K       + +A+K I++      Q Q+ + 
Sbjct: 115 ISPGEKW---ADRYEIDSLIGKGSFGQVVKAYDHTDNEQVAIKIIKNKKPFLNQAQIEVK 285

Query: 147 LDVVMRSSDCP---YIVQF-YGALFREGDCWICMELMSTSFDKFYKYVYSVLDDV----I 198
           L  +M   D     YIV+     +FR   C +  EL+S +       +Y +L +     +
Sbjct: 286 LLEMMNRHDTDNKYYIVRLKRHFMFRSHLCLV-FELLSYN-------LYDLLRNTNFRGV 441

Query: 199 PEEILGKITLATVKALNHLKE-NLKIIHRDIKPSNILL 235
              +  K       AL  L    + IIH D+KP NILL
Sbjct: 442 SLNLTRKFAQQLCTALLFLATPEMSIIHCDLKPENILL 555
>27546
          Length = 426

 Score = 36.2 bits (82), Expect = 0.023,   Method: Compositional matrix adjust.
 Identities = 18/39 (46%), Positives = 25/39 (64%)
 Frame = -1

Query: 211 VKALNHLKENLKIIHRDIKPSNILLDRSGNIKLCDFGIS 249
            KAL +L  +  I HRD+K  NILL +  N+K+ DFG +
Sbjct: 150 AKALQYLHSH-DIAHRDLKCENILLSKRLNVKIADFGFA 37
>14477
          Length = 493

 Score = 36.2 bits (82), Expect = 0.025,   Method: Compositional matrix adjust.
 Identities = 43/154 (27%), Positives = 82/154 (53%), Gaps = 6/154 (3%)
 Frame = -1

Query: 105 EIGRGAYGSVNKMVHKPSGQIM--AVKRIRST-VDEKEQKQLLMDLDVVMRSSDCPYIVQ 161
           ++G G +GSV K V +   + +  A+K +++  +D   Q +L+ + +V M+  D  +IV+
Sbjct: 469 KLGAGNFGSVMKGVCRLDDREIPVAIKVLKNADLDPSVQSELIKEAEV-MKKMDHMHIVR 293

Query: 162 FYGALFREGDCW-ICMELMSTS-FDKFY-KYVYSVLDDVIPEEILGKITLATVKALNHLK 218
             G    EG+   + +EL      +KF  K  +  L +++  E++ +++    + + +L+
Sbjct: 292 LIG--LCEGETMMLVLELAKLGPLNKFLPKNKHLPLWNIL--ELMWQVS----QGMEYLE 137

Query: 219 ENLKIIHRDIKPSNILLDRSGNIKLCDFGISGQL 252
            N K +HRD+   NILL      K+ DFG+S  L
Sbjct: 136 AN-KFVHRDLAARNILLCDEHFAKISDFGMSKTL 38
>36481
          Length = 806

 Score = 35.0 bits (79), Expect = 0.051,   Method: Compositional matrix adjust.
 Identities = 38/145 (26%), Positives = 61/145 (42%), Gaps = 5/145 (3%)
 Frame = +2

Query: 96  TAEDLKDLGEIGRGAYGSVNKMVHKPSGQIMAVKRIRSTVDEKEQKQLLMDLDVVMRSSD 155
           +  D+K     G G +G V +      G  +A+K I++    +E  +L +++   +R  D
Sbjct: 356 STNDMKLCPHWGEGTFGKVVQCKDLLKGDDIALKIIKNVDKYREAAKLEINVLEKLREKD 535

Query: 156 CPY----IVQFYGALFREGDCWICMELMSTS-FDKFYKYVYSVLDDVIPEEILGKITLAT 210
            P+     VQ        G   I   ++  S FD      Y       P E +  I+   
Sbjct: 536 -PHAKHMCVQMLDWFDYHGHVCISFHMLGLSVFDFLKDNSYGAY----PIEQVRHISYQL 700

Query: 211 VKALNHLKENLKIIHRDIKPSNILL 235
             A+N L EN ++ H D+KP NIL 
Sbjct: 701 CYAVNFLHEN-QLTHTDLKPENILF 772
>20152
          Length = 445

 Score = 34.7 bits (78), Expect = 0.069,   Method: Compositional matrix adjust.
 Identities = 24/89 (26%), Positives = 41/89 (46%), Gaps = 4/89 (4%)
 Frame = +1

Query: 281 GYDVRS-DVWSLGITLYELATGRFPYPKWNSVFDQLTQVVKGD---PPQLSNSEEREFSP 336
            YD  + DVWSLG+ LY L  G  P+ + N   + LT ++      PP +S+  +     
Sbjct: 22  SYDAPAVDVWSLGVILYMLVVGEAPFQEAND-SETLTMIMDCRYQIPPHISHKCQ----- 183

Query: 337 SFINFVNLCLTKDESKRPKYKELLKHPFI 365
              + +   L ++   R     +L HP++
Sbjct: 184 ---DLIEKMLQREPVDRASLPHILAHPWL 261
>27274
          Length = 396

 Score = 34.3 bits (77), Expect = 0.085,   Method: Composition-based stats.
 Identities = 22/86 (25%), Positives = 42/86 (48%), Gaps = 7/86 (8%)
 Frame = -1

Query: 287 DVWSLGITLYELATGRFPY-PKWNS------VFDQLTQVVKGDPPQLSNSEEREFSPSFI 339
           D+WSLGI L+EL +G  P+ P+  S      +     Q+++G    + +      S    
Sbjct: 339 DMWSLGILLHELLSGHVPFEPERGSRQMARNMMAVYAQIIRGSSRDVCDG--LALSTHGA 166

Query: 340 NFVNLCLTKDESKRPKYKELLKHPFI 365
           +F+   +  +++KR   ++   HP+I
Sbjct: 165 DFLRRLVQLEDTKRLTSQQAFSHPWI 88
>32000
          Length = 644

 Score = 34.3 bits (77), Expect = 0.097,   Method: Compositional matrix adjust.
 Identities = 34/152 (22%), Positives = 65/152 (42%), Gaps = 24/152 (15%)
 Frame = -1

Query: 238 SGNIKLCDFGISGQLVDSI-AKTRDAGCRPYMAPERIDPSASRQGYDVRSDVWSLGITLY 296
           +  +K+ DFG++      +   T +     Y APE +      + Y V  D+WSLG    
Sbjct: 581 TAKMKIADFGLARVFGLPVRTYTHEVITLWYRAPEIL---LGCRFYSVPVDIWSLGCIFV 411

Query: 297 ELATGRFPYPKWNSVFDQLTQVVK--GDPPQL---SNSEEREFSPSF------------- 338
           E+ T R  +P  +S  DQL ++ +  G P +      S+  ++ P+F             
Sbjct: 410 EMMTRRALFPG-DSEIDQLYRIFRTLGTPDEKVWPGVSKLPDYKPTFPKWPLKNLETVVS 234

Query: 339 -----INFVNLCLTKDESKRPKYKELLKHPFI 365
                ++ +   LT + ++R   +  ++HP+ 
Sbjct: 233 LSKVGLDLLKRMLTYNPNRRISARSAMRHPYF 138
>17637
          Length = 447

 Score = 33.9 bits (76), Expect = 0.12,   Method: Compositional matrix adjust.
 Identities = 24/80 (30%), Positives = 39/80 (48%), Gaps = 4/80 (5%)
 Frame = +1

Query: 232 NILLDRSGNIKLCDFGISGQLVDSIAKT-RDAGCRP--YMAPERIDPSASRQGYDVRSDV 288
           N ++D    +KL D  +S  L         D   RP  +++ E +  S   +G    SDV
Sbjct: 1   NCVIDDQLRVKLTDSALSRDLFSGDYNCLGDGEYRPIKWLSLEALQKSHYNEG----SDV 168

Query: 289 WSLGITLYELAT-GRFPYPK 307
           WS G+ ++E+ T G+ PY +
Sbjct: 169 WSFGVLMWEMCTLGKLPYAE 228
>18663
          Length = 600

 Score = 33.9 bits (76), Expect = 0.13,   Method: Compositional matrix adjust.
 Identities = 16/43 (37%), Positives = 23/43 (53%)
 Frame = +2

Query: 263 GCRPYMAPERIDPSASRQGYDVRSDVWSLGITLYELATGRFPY 305
           G   Y+APE +      + Y    D W+LG+ LYE+  GR P+
Sbjct: 14  GTPNYIAPEIL----RGEDYGFSVDWWALGVLLYEMLAGRSPF 130
>32691
          Length = 295

 Score = 32.7 bits (73), Expect = 0.28,   Method: Composition-based stats.
 Identities = 19/54 (35%), Positives = 27/54 (50%)
 Frame = +1

Query: 333 EFSPSFINFVNLCLTKDESKRPKYKELLKHPFILMYEERTVEVACYVCKILDQM 386
           ++S  FI+FV+ CL K+   R    +LL+H FI   E          C+IL  M
Sbjct: 82  KWSTEFIDFVSKCLVKNPENRATAVDLLQHDFIKKAE---------ACEILQAM 216
>29590
          Length = 320

 Score = 32.3 bits (72), Expect = 0.34,   Method: Compositional matrix adjust.
 Identities = 20/63 (31%), Positives = 33/63 (52%), Gaps = 1/63 (1%)
 Frame = +3

Query: 244 CDFGISGQLVDSIAKTRDA-GCRPYMAPERIDPSASRQGYDVRSDVWSLGITLYELATGR 302
           CD G +  L ++    RD  G   Y+APE +D     +   +++D+WSLG+  Y + T  
Sbjct: 3   CDLGFAC-LTNTGEDIRDIIGTPDYVAPEVLD----YEPLSIQTDMWSLGVLSYVMLTAC 167

Query: 303 FPY 305
            P+
Sbjct: 168 SPF 176
>32957
          Length = 645

 Score = 32.3 bits (72), Expect = 0.37,   Method: Compositional matrix adjust.
 Identities = 20/45 (44%), Positives = 23/45 (51%), Gaps = 1/45 (2%)
 Frame = +3

Query: 255 SIAKTRD-AGCRPYMAPERIDPSASRQGYDVRSDVWSLGITLYEL 298
           S  +TR   G R YMAPE       R+ Y    D W LGI L+EL
Sbjct: 24  SGGRTRTFCGTREYMAPE----VHERKEYGKEVDWWGLGILLHEL 146
>26156
          Length = 479

 Score = 32.0 bits (71), Expect = 0.40,   Method: Compositional matrix adjust.
 Identities = 18/77 (23%), Positives = 41/77 (53%), Gaps = 2/77 (2%)
 Frame = -1

Query: 106 IGRGAYGSVNKMVHKPSGQIMAVKRIRSTV--DEKEQKQLLMDLDVVMRSSDCPYIVQFY 163
           IGRG+Y  V ++ HK + +I A+K I+  +  D+++   +  +  V   +++ P++V  +
Sbjct: 365 IGRGSYAKVLQVEHKRTKRIYAMKVIKKELVNDDEDIDWVQTEKHVFETATNYPFLVGLH 186

Query: 164 GALFREGDCWICMELMS 180
                E   +  +E ++
Sbjct: 185 SCFQSESRLFFVIEFVN 135
>20559
          Length = 430

 Score = 31.2 bits (69), Expect = 0.78,   Method: Compositional matrix adjust.
 Identities = 13/30 (43%), Positives = 22/30 (73%)
 Frame = -2

Query: 103 LGEIGRGAYGSVNKMVHKPSGQIMAVKRIR 132
           L +IG G YG+V K  ++ + +I+A+KR+R
Sbjct: 360 LEKIGEGTYGTVFKAKNRETHEIVALKRVR 271
>21800
          Length = 855

 Score = 30.8 bits (68), Expect = 0.90,   Method: Compositional matrix adjust.
 Identities = 16/38 (42%), Positives = 21/38 (55%)
 Frame = +2

Query: 198 IPEEILGKITLATVKALNHLKENLKIIHRDIKPSNILL 235
           IP   +  I    ++ LN+L     IIH DIKP NIL+
Sbjct: 623 IPVHNVKLIIRQVLEGLNYLHAKCNIIHTDIKPENILI 736
>13305
          Length = 549

 Score = 30.8 bits (68), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 22/81 (27%), Positives = 36/81 (44%), Gaps = 3/81 (3%)
 Frame = +2

Query: 282 YDVRSDVWSLGITLYELAT-GRFPYPKWNS--VFDQLTQVVKGDPPQLSNSEEREFSPSF 338
           Y  +SDVWS G+ L+E+ T G  PY   ++  +F  L    +   P+L +          
Sbjct: 56  YTTQSDVWSFGVVLWEIFTLGGTPYSSTDTQQLFAFLKDGYRLKRPKLCDQNTYAMMLQ- 232

Query: 339 INFVNLCLTKDESKRPKYKEL 359
                 C  ++  +RP + EL
Sbjct: 233 ------CWNENAQRRPTFPEL 277
>26874
          Length = 391

 Score = 30.8 bits (68), Expect = 1.1,   Method: Composition-based stats.
 Identities = 18/43 (41%), Positives = 24/43 (55%), Gaps = 2/43 (4%)
 Frame = -3

Query: 309 NSVFDQLTQVVK--GDPPQLSNSEEREFSPSFINFVNLCLTKD 349
           N+ FDQL  VV   GD  QLS  E  + + ++IN +   L KD
Sbjct: 314 NTAFDQLRAVVPSVGDDRQLSKYETLQMAQTYINALQELLDKD 186
>29360
          Length = 363

 Score = 30.0 bits (66), Expect = 1.8,   Method: Compositional matrix adjust.
 Identities = 28/120 (23%), Positives = 58/120 (48%), Gaps = 4/120 (3%)
 Frame = +3

Query: 120 KPSGQIMAVKRIRSTVDEKEQKQLLMDLDVVMR----SSDCPYIVQFYGALFREGDCWIC 175
           K + +I+A+K +++      Q Q+  ++ ++ R    S+D    V+ +     +    + 
Sbjct: 18  KGTSEIVAIKILKNHPSYARQGQI--EVSILQRLSQESADDYNFVRAFECFQHKNHTCLV 191

Query: 176 MELMSTSFDKFYKYVYSVLDDVIPEEILGKITLATVKALNHLKENLKIIHRDIKPSNILL 235
            E++  +    Y ++       +P + +  IT   + AL  LK+ L +IH D+KP NI+L
Sbjct: 192 FEMLEQNL---YDFLKQNKFQPLPLKYIRPITQQVLTALRKLKQ-LGLIHADLKPENIML 359
>01106
          Length = 878

 Score = 30.0 bits (66), Expect = 1.9,   Method: Compositional matrix adjust.
 Identities = 14/38 (36%), Positives = 22/38 (57%)
 Frame = +3

Query: 198 IPEEILGKITLATVKALNHLKENLKIIHRDIKPSNILL 235
           IP   +  I    ++ L+++    +IIH DIKP NIL+
Sbjct: 636 IPIHNVKLIIRQVLEGLSYMHAKCRIIHTDIKPENILI 749
>15549
          Length = 470

 Score = 28.5 bits (62), Expect = 4.7,   Method: Compositional matrix adjust.
 Identities = 15/46 (32%), Positives = 26/46 (56%)
 Frame = -1

Query: 97  AEDLKDLGEIGRGAYGSVNKMVHKPSGQIMAVKRIRSTVDEKEQKQ 142
           A++ + + ++G+G YG V +  +K   Q  AVKRI    D   +K+
Sbjct: 221 ADEFECIEQMGKGGYGIVFRAKNKVDEQEYAVKRIALPSDAAVKKR 84
>16350
          Length = 1108

 Score = 28.5 bits (62), Expect = 4.9,   Method: Compositional matrix adjust.
 Identities = 10/23 (43%), Positives = 14/23 (60%)
 Frame = +2

Query: 281 GYDVRSDVWSLGITLYELATGRF 303
           GY   +D+WS     +ELATG +
Sbjct: 458 GYGTPADIWSTACMAFELATGDY 526
>31489
          Length = 329

 Score = 28.5 bits (62), Expect = 5.6,   Method: Compositional matrix adjust.
 Identities = 17/64 (26%), Positives = 34/64 (53%)
 Frame = +3

Query: 171 DCWICMELMSTSFDKFYKYVYSVLDDVIPEEILGKITLATVKALNHLKENLKIIHRDIKP 230
           D  +  +LM +     ++ +YS  D  + EE +       ++ L ++  +  ++HRD+KP
Sbjct: 90  DIHVVFDLMESDL---HRIIYS--DQPLTEEHIRYFLYQILRGLKYI-HSANVVHRDLKP 251

Query: 231 SNIL 234
           SN+L
Sbjct: 252 SNLL 263
>31120
          Length = 439

 Score = 28.1 bits (61), Expect = 6.0,   Method: Compositional matrix adjust.
 Identities = 18/85 (21%), Positives = 40/85 (47%)
 Frame = +1

Query: 286 SDVWSLGITLYELATGRFPYPKWNSVFDQLTQVVKGDPPQLSNSEEREFSPSFINFVNLC 345
           +D WSLG+ L+ +  G+ P+   +S  ++L +  +          +   SP+  + V++ 
Sbjct: 37  ADAWSLGVILFIMLNGKMPFD--DSNLNKLLEDQRSKKYSFRRKLQDLVSPNARSTVSVL 210

Query: 346 LTKDESKRPKYKELLKHPFILMYEE 370
           L  + + R    E+L   ++   +E
Sbjct: 211 LEPNSAMRWDLNEVLNCQWLQTIDE 285
>22398
          Length = 941

 Score = 27.7 bits (60), Expect = 7.9,   Method: Compositional matrix adjust.
 Identities = 30/130 (23%), Positives = 52/130 (40%), Gaps = 27/130 (20%)
 Frame = +2

Query: 51  VKSTARFTLNPNTTGV---QNPHIE-RLRTHSIESSGKLKIS----PEQHWDFTAEDL-- 100
           +KS   F LN     +    N H+E +   H +  +  L+ S    P  +   T  D   
Sbjct: 260 IKSNIYFVLNSKIALLVLTLNIHLE*KANVHLVPRAKMLRSSQRPNPNHNVHLTLFDFIP 439

Query: 101 -KDLGEIGRGAYGSVNKMVHKPSGQ----------------IMAVKRIRSTVDEKEQKQL 143
            +    +GR A+ S+ ++VH   GQ                ++    +R+T   K  K+ 
Sbjct: 440 SRTFSTLGRNAHSSLGQIVHSTLGQNEHLTSVLFPAEC*PNVLDTTELRNTNKRKHPKKK 619

Query: 144 LMDLDVVMRS 153
            +DL ++M S
Sbjct: 620 SVDLVILMLS 649
>20160
          Length = 1277

 Score = 27.7 bits (60), Expect = 8.5,   Method: Compositional matrix adjust.
 Identities = 18/69 (26%), Positives = 28/69 (40%), Gaps = 11/69 (15%)
 Frame = +2

Query: 308 WNSVFDQLTQVVKGD-----------PPQLSNSEEREFSPSFINFVNLCLTKDESKRPKY 356
           +N VF Q+ Q   GD           P   +     E      + +N C+  D S RP  
Sbjct: 215 YNLVFRQILQCKGGDTRRHRWGLRIEPGTQNGQYACENDEDAADLINRCIALDPSTRPVL 394

Query: 357 KELLKHPFI 365
            ++LKH ++
Sbjct: 395 ADILKHKWM 421
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|28173550|ref|NP_033989.2| cell division cycle 10
homolog [Mus musculus]
         (437 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

14132                                                                 237   6e-63
29788                                                                 128   6e-30
34156                                                                 105   5e-23
22078                                                                  83   2e-16
14677                                                                  69   3e-16
38061                                                                  31   0.76 
14625                                                                  30   2.1  
21913                                                                  28   7.9  
>14132
          Length = 422

 Score =  237 bits (605), Expect = 6e-63,   Method: Compositional matrix adjust.
 Identities = 106/140 (75%), Positives = 125/140 (89%), Gaps = 2/140 (1%)
 Frame = -2

Query: 117 FGDAVDNSNCWQPVIDYIDSKFEDYLNAESRVNRRQMPDNRVQCCLYFIAPSGHGLKPLD 176
           FGDAVDNSNCWQP+ DYIDSK+E+YLNAESRVNR  MPD RV CCLYFIAP+GHGLKPLD
Sbjct: 421 FGDAVDNSNCWQPITDYIDSKYEEYLNAESRVNRTVMPDTRVHCCLYFIAPTGHGLKPLD 242

Query: 177 IEFMKRLHEKVNIIPLIAKADTLTPEECQQFKKQIMKEIQEHKIKIYEFPETDDEEENKL 236
           +EFMKRLH+KVNIIPL+AKADTLTP+EC++FKK I+ EI +HKIKIYEFP+ DDEEE K+
Sbjct: 241 VEFMKRLHDKVNIIPLVAKADTLTPDECREFKKTILNEIAQHKIKIYEFPDCDDEEEMKI 62

Query: 237 VKKIK--DRLPLAVVGSNTI 254
            K+++  DR+P AVVGSN +
Sbjct: 61  QKRLRVSDRVPFAVVGSNRV 2
>29788
          Length = 687

 Score =  128 bits (321), Expect = 6e-30,   Method: Compositional matrix adjust.
 Identities = 70/126 (55%), Positives = 78/126 (61%)
 Frame = +3

Query: 268 PWGVAEVENGEHCDFTILRNMLIRTHMQDLKDVTNNVHYENYRSRKLAAVTYNGVDNNKN 327
           PWG+ EVEN EH DF  LRNMLIRTHMQDLKDVTNNVHYEN+R  KLA  T  G      
Sbjct: 3   PWGIVEVENLEHNDFIALRNMLIRTHMQDLKDVTNNVHYENFRYNKLAPSTTEG---KVK 173

Query: 328 KGQLTKSPLAQMEEERREHVAXXXXXXXXXXXXXXXXXXXXXXXLKDSEAELQRRHEQMK 387
            G L K PL+QM EER+EH+                        LKDSEA+LQ+R EQMK
Sbjct: 174 PGALAKDPLSQMAEERQEHMVKMKKMEAEMEQVFEMKVKEKKQKLKDSEADLQKRSEQMK 353

Query: 388 KNLEAQ 393
           K+LE Q
Sbjct: 354 KSLEQQ 371
>34156
          Length = 348

 Score =  105 bits (261), Expect = 5e-23,   Method: Composition-based stats.
 Identities = 53/79 (67%), Positives = 66/79 (83%), Gaps = 1/79 (1%)
 Frame = -1

Query: 37  PNQVYRKSVKRGFEFTLMVVGESGLGKSTLINSLFLTDLYSPEY-PGPSHRIKKTVQVEQ 95
           P QV+RKSVK+GFEFTLMVVGESGLGKSTL+NSLFLTDLY   + P  S +I++TV+++ 
Sbjct: 237 PTQVHRKSVKKGFEFTLMVVGESGLGKSTLVNSLFLTDLYPERHIPSASEKIQQTVKIDA 58

Query: 96  SKVLIKEGGVQLLLTIVDT 114
           S V I+E GV+L LT+VDT
Sbjct: 57  STVEIEERGVKLRLTVVDT 1
>22078
          Length = 417

 Score = 82.8 bits (203), Expect = 2e-16,   Method: Composition-based stats.
 Identities = 36/49 (73%), Positives = 41/49 (83%)
 Frame = +3

Query: 263 RGRQYPWGVAEVENGEHCDFTILRNMLIRTHMQDLKDVTNNVHYENYRS 311
           RGR YPWG+ EV+N  HCDF  LR MLI THMQDLKDVT++VHYEN+RS
Sbjct: 3   RGRAYPWGIVEVDNXSHCDFIRLRQMLISTHMQDLKDVTSDVHYENFRS 149
>14677
          Length = 378

 Score = 69.3 bits (168), Expect(2) = 3e-16,   Method: Composition-based stats.
 Identities = 30/67 (44%), Positives = 45/67 (67%), Gaps = 2/67 (2%)
 Frame = -1

Query: 100 IKEGGVQLLLTIVDTPGFGDAVDNSNCWQPVIDYIDSKFEDYLNAESRVNR--RQMPDNR 157
           + E  V+L LT VDT GFGD ++ ++ W+P++DYID++F+ YL  E ++ R      D+R
Sbjct: 201 LTEKNVRLKLTTVDTTGFGDQINKADSWKPIVDYIDAQFDAYLQEELKIKRMLHSYHDSR 22

Query: 158 VQCCLYF 164
           V  CLYF
Sbjct: 21  VHACLYF 1

 Score = 33.1 bits (74), Expect(2) = 3e-16,   Method: Composition-based stats.
 Identities = 14/26 (53%), Positives = 21/26 (80%)
 Frame = -3

Query: 52  TLMVVGESGLGKSTLINSLFLTDLYS 77
           T  V+GE+G+GKSTL+++LF T+  S
Sbjct: 334 TFFVLGETGIGKSTLMDTLFNTNFDS 257
>38061
          Length = 206

 Score = 31.2 bits (69), Expect = 0.76,   Method: Composition-based stats.
 Identities = 13/30 (43%), Positives = 18/30 (60%)
 Frame = +3

Query: 240 IKDRLPLAVVGSNTIIEVNGKRVRGRQYPW 269
           +   LP AVVGSN  +++  K V+ RQ  W
Sbjct: 117 MNSHLPFAVVGSNDEVKIGNKMVKARQGSW 206
>14625
          Length = 846

 Score = 30.0 bits (66), Expect = 2.1,   Method: Compositional matrix adjust.
 Identities = 23/86 (26%), Positives = 37/86 (43%)
 Frame = +3

Query: 140 DYLNAESRVNRRQMPDNRVQCCLYFIAPSGHGLKPLDIEFMKRLHEKVNIIPLIAKADTL 199
           D +NA  RV  R   D+++      +   G    P ++  + R+H K  +     K + L
Sbjct: 141 DCVNAHKRV--RMTKDHQLTSLEEALTNQGGSSGPTEVSMLCRVHPKEKLTLFCEKCEVL 314

Query: 200 TPEECQQFKKQIMKEIQEHKIKIYEF 225
           T  +CQ  +       QEHK   Y+F
Sbjct: 315 TCRDCQLLQH------QEHK---YQF 365
>21913
          Length = 874

 Score = 28.1 bits (61), Expect = 7.9,   Method: Compositional matrix adjust.
 Identities = 12/40 (30%), Positives = 24/40 (60%)
 Frame = +3

Query: 191 PLIAKADTLTPEECQQFKKQIMKEIQEHKIKIYEFPETDD 230
           PL  +A TL  ++  QF++ + + +Q  K ++ + P +DD
Sbjct: 381 PLNPEAATLYEQDTDQFRQHVSESVQTAKQRLMQPPASDD 500
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|9910474|ref|NP_064323.1| membrane protein,
palmitoylated 3 (MAGUK p55 subfamily member 6) [Mus musculus]
         (539 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

13641                                                                 235   7e-63
27435                                                                 148   5e-36
35802                                                                 143   1e-34
11512                                                                 131   7e-31
29974                                                                  88   8e-18
37412                                                                  78   8e-15
29636                                                                  67   1e-11
11574                                                                  56   4e-08
33158                                                                  55   6e-08
29687                                                                  37   0.019
01494                                                                  35   0.095
20073                                                                  33   0.27 
26154                                                                  32   0.58 
30740                                                                  32   0.79 
32054                                                                  30   1.7  
25304                                                                  30   2.1  
01169                                                                  30   3.6  
33804                                                                  29   4.7  
28578                                                                  28   8.4  
>13641
          Length = 2081

 Score =  235 bits (599), Expect(2) = 7e-63,   Method: Compositional matrix adjust.
 Identities = 139/354 (39%), Positives = 199/354 (56%), Gaps = 23/354 (6%)
 Frame = +2

Query: 197 SGSVTLKILPSYRDTITP----QQVFVKCHFDYNPFNDNLIPCKEAGLKFSKGEILQIVN 252
           SGS+TLK++PS R   TP    +++ VK  F +N   D+ IPCKEAGL F +G+IL IVN
Sbjct: 89  SGSLTLKLVPSRR---TPGSKKREMVVKAMFSFNSKLDDNIPCKEAGLSFQQGDILHIVN 259

Query: 253 REDPNWWQA-SHVKEGGSAGLIPSQFLEEKRKAFVRRDWDNSGPFCGTIS---------- 301
           +ED  WWQA  H      AGLIPS+   E+++   +           +IS          
Sbjct: 260 QEDAIWWQAYKHGDAKKRAGLIPSRHYHERQEVLRKSKSKEGRHMARSISPCRYSPKVPK 439

Query: 302 NKKKKKMMYLTTRNA---EFDRHEIQIYEEVAKMPPFQR--KTLVLIGAQGVGRRSLKNR 356
            ++ +K MY   +N    +FD  EI  Y+EV    P  R  + +VLIGA G+GR  LK R
Sbjct: 440 QRRLRKTMYHIVQNGALTDFDTDEIPAYDEVEHFTPKPRHFRPIVLIGAPGIGRNELKRR 619

Query: 357 FIVLNPARFGTTVPFTSRKPREEQKDGQAYKFVSRSEMEADIKAGKYLEHGEYEGNLYGT 416
               NP  F   VP+T+R  +  ++DG+ Y FVSR +ME  I A K++E+GE+ G+LYGT
Sbjct: 620 LKASNPMHFLEVVPYTTRTKKPFEEDGKEYHFVSREDMEESIIAQKFVEYGEHHGHLYGT 799

Query: 417 KIDSILEVVQTGRTCILDVNPQALKVLRTSEFMPYVVFIAAPELETL---RAMHKAVVDA 473
            ++SI +V+  G+ C+L  + QALK LRT E  PYV+FI +P LE L   R   +A    
Sbjct: 800 SVESIKQVIAAGKVCLLTPHTQALKFLRTYELKPYVIFIKSPTLEKLKESRMPARARATE 979

Query: 474 GITTKLLTDSDLKKTVDESARIQRAYNHYFDLIIVNDNLDKAFEKLQTAIEKLR 527
             + +  +  +L++  + S R++  Y H FD+ IVND+L  A  +L     K R
Sbjct: 980 ADSIRPFSIEELEEMAETSRRLEERYGHVFDITIVNDSLTDATTELLMVASK*R 1141

 Score = 24.3 bits (51), Expect(2) = 7e-63,   Method: Compositional matrix adjust.
 Identities = 8/13 (61%), Positives = 10/13 (76%)
 Frame = +1

Query: 525  KLRMEPQWVPISW 537
            K+  EPQWVP+ W
Sbjct: 1132 KIEKEPQWVPVGW 1170
>27435
          Length = 456

 Score =  148 bits (374), Expect = 5e-36,   Method: Compositional matrix adjust.
 Identities = 63/157 (40%), Positives = 108/157 (68%)
 Frame = +1

Query: 380 QKDGQAYKFVSRSEMEADIKAGKYLEHGEYEGNLYGTKIDSILEVVQTGRTCILDVNPQA 439
           + +G+ Y F++R+  EAD+ +GK++E+GE++GNLYGT ++++ +V+Q GR CIL++ P++
Sbjct: 1   EHNGKDYHFITRAVFEADMLSGKFVEYGEFQGNLYGTTVEAVRQVIQQGRICILNLGPES 180

Query: 440 LKVLRTSEFMPYVVFIAAPELETLRAMHKAVVDAGITTKLLTDSDLKKTVDESARIQRAY 499
           LK LR +E  PY++FI+ P +E LR +  A     +     TD  +K+ ++    ++  Y
Sbjct: 181 LKNLRETELKPYIIFISPPXMEKLRQLQMA-----LGKPRPTDDQVKEVIERGREMEEMY 345

Query: 500 NHYFDLIIVNDNLDKAFEKLQTAIEKLRMEPQWVPIS 536
           +HYFD I+VN  L++AF++L   I ++  EPQWVPI+
Sbjct: 346 SHYFDYILVNMELNRAFDELLQEINRIETEPQWVPIT 456
>35802
          Length = 571

 Score =  143 bits (361), Expect = 1e-34,   Method: Compositional matrix adjust.
 Identities = 61/156 (39%), Positives = 104/156 (66%)
 Frame = +1

Query: 383 GQAYKFVSRSEMEADIKAGKYLEHGEYEGNLYGTKIDSILEVVQTGRTCILDVNPQALKV 442
           G+ Y F SRS  EAD+ +GK+LE+GE++ NLYGT ++++ +V+  GR C+L++ P++LK+
Sbjct: 10  GRDYHFTSRSMFEADMLSGKFLEYGEFQSNLYGTSVEAVRQVILQGRVCLLNLEPESLKI 189

Query: 443 LRTSEFMPYVVFIAAPELETLRAMHKAVVDAGITTKLLTDSDLKKTVDESARIQRAYNHY 502
           LR ++  PY  F+  P +E LR +H A+    I     TD  LK  +D+   ++  Y H+
Sbjct: 190 LRETDLKPYTXFVCPPNMEKLRQLHIAM--GKIRP---TDDQLKTVMDKGREMEDMYGHF 354

Query: 503 FDLIIVNDNLDKAFEKLQTAIEKLRMEPQWVPISWV 538
           FD  +VN ++D++ ++L   I ++ +EPQWVP++W+
Sbjct: 355 FDYKLVNMDVDRSVQELMAEINRIEVEPQWVPVTWM 462
>11512
          Length = 1006

 Score =  131 bits (329), Expect = 7e-31,   Method: Compositional matrix adjust.
 Identities = 64/158 (40%), Positives = 95/158 (60%), Gaps = 5/158 (3%)
 Frame = -3

Query: 386  YKFVSRSEMEADIKAGKYLEHGEYEGNLYGTKIDSILEVVQTGRTCILDVNPQALKVLRT 445
            Y FV+R +M+ADI+AGK++EHGEY+G+LYGT  +S+  +V  G  C+L  + QA+K LRT
Sbjct: 1004 YIFVAREKMDADIEAGKFVEHGEYKGHLYGTSAESVKSIVNAGCVCVLSPHYQAIKTLRT 825

Query: 446  SEFMPYVVFIAAPELETLR-----AMHKAVVDAGITTKLLTDSDLKKTVDESARIQRAYN 500
             +  P+++ I  PEL+ L+     A  K+  D     +  TD + +  +  + RI   Y 
Sbjct: 824  XQLKPFLIHIKPPELDILKSTRTEARAKSTFDEA-NARSFTDEEFEDMIKSTXRIDFTYG 648

Query: 501  HYFDLIIVNDNLDKAFEKLQTAIEKLRMEPQWVPISWV 538
            H+FD+ IVN  L  AFE L   +++L  EP W P  WV
Sbjct: 647  HFFDVEIVNGELLAAFEXLVQHVQRLENEPLWAPSMWV 534
>29974
          Length = 344

 Score = 88.2 bits (217), Expect = 8e-18,   Method: Compositional matrix adjust.
 Identities = 43/100 (43%), Positives = 62/100 (62%), Gaps = 1/100 (1%)
 Frame = +1

Query: 362 PARFGTTVPFTSRKPREEQKDGQAYKFVS-RSEMEADIKAGKYLEHGEYEGNLYGTKIDS 420
           P +FG+ +P T+R+ R  ++ GQ Y FVS R +ME DI+   ++E G Y  NLYGT + S
Sbjct: 25  PDKFGSCIPHTTRERRTNEEPGQDYHFVSSREQMERDIQNHLFIEAGVYNDNLYGTSVAS 204

Query: 421 ILEVVQTGRTCILDVNPQALKVLRTSEFMPYVVFIAAPEL 460
           + EV + GR CILDV+  A+K L+ +   P  +FI    L
Sbjct: 205 VKEVAEQGRHCILDVSGNAIKRLQVAGLYPIAIFIKPSRL 324
>37412
          Length = 757

 Score = 78.2 bits (191), Expect = 8e-15,   Method: Compositional matrix adjust.
 Identities = 44/140 (31%), Positives = 75/140 (53%), Gaps = 7/140 (5%)
 Frame = -1

Query: 391 RSEMEADIKAGKYLEHGEYEGNLYGTKIDSILEVVQTGRTCILDVNPQALKVLRTSEFMP 450
           R  ME+DI +G+YLE+G++ GNLYGT++D++ ++V +GR           K  R     P
Sbjct: 739 RLTMESDIMSGRYLEYGDFNGNLYGTRLDTVRQIVDSGRCVCWTSTLPH*KSSRRPSSCP 560

Query: 451 YVVFIAAPELETLRAMHKAVVDAGITTKLLTDSDLK-------KTVDESARIQRAYNHYF 503
                ++P L    +     +D G+     +  +LK       +T+ ES +I+R Y  YF
Sbjct: 559 --TLCSSPRLAWKLSKSCTKMDDGLHAAAGSVVELK*NGGNFIETMKESQQIERVYASYF 386

Query: 504 DLIIVNDNLDKAFEKLQTAI 523
           D IIVND+ +  + +L+ ++
Sbjct: 385 DDIIVNDSFEDTYRQLRRSL 326

 Score = 63.2 bits (152), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 39/119 (32%), Positives = 64/119 (53%), Gaps = 10/119 (8%)
 Frame = -3

Query: 428 GRTCILDVNPQALKVLRTSEFMPYVVFIAAPELETLRAMHK--------AVVDAGITTKL 479
           G+ C+LDVNP +LKVL+T+EF+PY+VFIAAP +E L+ M++        +    G+  K 
Sbjct: 629 GKMCVLDVNPTSLKVLKTAEFLPYIVFIAAPSVEALKVMYEDGRRFARGSRERGGVEMKR 450

Query: 480 --LTDSDLKKTVDESARIQRAYNHYFDLIIVNDNLDKAFEKLQTAIEKLRMEPQWVPIS 536
             L   D ++  D +   Q    ++   +       +    + + I++L  E QWVP+S
Sbjct: 449 XKLH*DDEREPADRACVCQLL**YHRQRL-----F*RHLPSVASLIDELTSEQQWVPVS 288
>29636
          Length = 354

 Score = 67.4 bits (163), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 34/93 (36%), Positives = 54/93 (58%), Gaps = 7/93 (7%)
 Frame = +1

Query: 199 SVTLKILPSYR----DTITPQQVF-VKCHFDYNPFNDNLIPCKEAGLKFSKGEILQIVNR 253
           ++T  I+P++      T  P  +  ++  F+Y+P +D  IPC+E G+ F KG+IL  +  
Sbjct: 1   TITFMIIPAHSCVEDTTAKPGDIMHLRALFNYDPEDDPYIPCRELGISFLKGDILHAIQL 180

Query: 254 EDPNWWQASHVKEGGS--AGLIPSQFLEEKRKA 284
            D NWWQA    E     AGLIPS+  +E+R++
Sbjct: 181 SDSNWWQAHREGEDAHMLAGLIPSKAFQEQRES 279
>11574
          Length = 1255

 Score = 56.2 bits (134), Expect = 4e-08,   Method: Compositional matrix adjust.
 Identities = 22/45 (48%), Positives = 33/45 (73%)
 Frame = +2

Query: 495 IQRAYNHYFDLIIVNDNLDKAFEKLQTAIEKLRMEPQWVPISWVY 539
           +++AY H+FD  IVN+++D+    L+ AIE +   PQWVP+SWVY
Sbjct: 14  VEKAYGHFFDRQIVNNDIDETIRTLEKAIEDVCTLPQWVPVSWVY 148
>33158
          Length = 1075

 Score = 55.5 bits (132), Expect = 6e-08,   Method: Compositional matrix adjust.
 Identities = 47/175 (26%), Positives = 89/175 (50%), Gaps = 13/175 (7%)
 Frame = +2

Query: 13  SSTGAEEIDLIFLKGIMENPIVKSLAKAHERLEDSKLEA-----VSDNNLELVNEILEDI 67
           SSTG +E+   FLK +  NP+ +     H+++ D    +     +  ++ EL  ++    
Sbjct: 575 SSTGQQEVH--FLKQLFHNPLFQQTVDMHQKMVDVTSRSPLPRPLGSDSQELACDVKSYG 748

Query: 68  TPLISVDEN--VAELVGILKEPHFQSLLEAHDIVASKCYDSPPSSPEMNIPSLN------ 119
           + +        V EL  +L +P  ++LL+AHD VA +      + P +++   +      
Sbjct: 749 SEMGGSXSEAVVEELSMLLDKPALKNLLKAHDEVADQ-----QTHPILHVSESDLIDYPL 913

Query: 120 NQLPVDAIRILGIHKKAGEPLGVTFRVENNDLVIARILHGGMIDRQGLLHVGDII 174
            +   ++++I+ + +K  E LG T + E + ++IARI+ GG  ++ GLLH GD I
Sbjct: 914 TEYGEESVKIIHL-EKTNEHLGATVKNEGDSVLIARIVKGGAAEKSGLLHEGDEI 1075
>29687
          Length = 434

 Score = 37.0 bits (84), Expect = 0.019,   Method: Compositional matrix adjust.
 Identities = 29/85 (34%), Positives = 41/85 (48%)
 Frame = -2

Query: 196 ISGSVTLKILPSYRDTITPQQVFVKCHFDYNPFNDNLIPCKEAGLKFSKGEILQIVNRED 255
           I GSV L I P+  D  T  ++ VK   DYN         +E  L F KG I+  V+R+D
Sbjct: 349 IYGSVDLYINPN--DFTT--KLRVKALHDYNA-------KREDELSFCKGAIITNVSRQD 203

Query: 256 PNWWQASHVKEGGSAGLIPSQFLEE 280
             WW+  +  +       PS ++EE
Sbjct: 202 GGWWRGDYGTK--KQHWFPSNYVEE 134
>01494
          Length = 2122

 Score = 34.7 bits (78), Expect = 0.095,   Method: Compositional matrix adjust.
 Identities = 21/62 (33%), Positives = 29/62 (46%)
 Frame = +3

Query: 219 VKCHFDYNPFNDNLIPCKEAGLKFSKGEILQIVNREDPNWWQASHVKEGGSAGLIPSQFL 278
           VK   DYN   D+        L F KG I+  V+R+D  WW+  +  +       PS F+
Sbjct: 312 VKALHDYNANRDD-------ELSFCKGAIITNVSRQDGGWWRGDYGAK--KQHWFPSNFV 464

Query: 279 EE 280
           EE
Sbjct: 465 EE 470
>20073
          Length = 582

 Score = 33.1 bits (74), Expect = 0.27,   Method: Compositional matrix adjust.
 Identities = 23/59 (38%), Positives = 34/59 (57%), Gaps = 1/59 (1%)
 Frame = +3

Query: 147 ENNDLVIARILHGGMIDRQGLLHVGDIIKEVNGHEV-GNNPKELQELLKNISGSVTLKI 204
           +++ + I+RI+ GG+ DR   L  GD +  VNG  V G   ++  ELLK   GSV L +
Sbjct: 36  QSSPIYISRIIPGGVADRLNCLKRGDQLLSVNGVSVEGEYHEKAVELLKLAQGSVRLVV 212
>26154
          Length = 446

 Score = 32.0 bits (71), Expect = 0.58,   Method: Composition-based stats.
 Identities = 16/55 (29%), Positives = 29/55 (52%), Gaps = 3/55 (5%)
 Frame = -3

Query: 135 KAGEPLGVTFRVENN---DLVIARILHGGMIDRQGLLHVGDIIKEVNGHEVGNNP 186
           + G PLG+T     +   ++VI+ +  GG+  + G +HVGD +  +N      +P
Sbjct: 210 RHGGPLGITISGTEDPLDNIVISELTAGGLAQKTGAMHVGDRLLGINESTTKTSP 46
>30740
          Length = 488

 Score = 31.6 bits (70), Expect = 0.79,   Method: Compositional matrix adjust.
 Identities = 10/22 (45%), Positives = 18/22 (81%)
 Frame = +2

Query: 240 LKFSKGEILQIVNREDPNWWQA 261
           L FSKG+IL+++++++  WW A
Sbjct: 233 LPFSKGDILELISKDEEEWWTA 298
>32054
          Length = 1421

 Score = 30.4 bits (67), Expect = 1.7,   Method: Compositional matrix adjust.
 Identities = 28/87 (32%), Positives = 43/87 (49%), Gaps = 1/87 (1%)
 Frame = +1

Query: 369  VPFTSRKPREEQ-KDGQAYKFVSRSEMEADIKAGKYLEHGEYEGNLYGTKIDSILEVVQT 427
            VP   RK RE Q  DG  Y      + E D+     LE   Y+  +  T+ +++LE+   
Sbjct: 1054 VPSLHRKHREIQLPDGCYYV----HQAENDVHNSSSLEI-YYQCGMQTTETNALLEL--- 1209

Query: 428  GRTCILDVNPQALKVLRTSEFMPYVVF 454
              TC + ++ Q   +LRT E + Y+VF
Sbjct: 1210 --TCQV-ISDQCFXILRTQEQLGYIVF 1281
>25304
          Length = 525

 Score = 30.4 bits (67), Expect = 2.1,   Method: Compositional matrix adjust.
 Identities = 12/22 (54%), Positives = 15/22 (68%)
 Frame = -2

Query: 219 VKCHFDYNPFNDNLIPCKEAGL 240
           +K HF+ NPF DN + CKE  L
Sbjct: 170 IKFHFESNPFFDNEVICKEFHL 105
>01169
          Length = 1267

 Score = 29.6 bits (65), Expect = 3.6,   Method: Compositional matrix adjust.
 Identities = 27/105 (25%), Positives = 53/105 (50%), Gaps = 5/105 (4%)
 Frame = +3

Query: 177 VNGHEVGNNPKELQELLKNISGSVTLKILPSYRDTITPQQVFVKCHFDYNPFNDNLIPC- 235
           VN   VG+  K++Q++ + + G     I+   ++T+  + +  + H D NP  + L+PC 
Sbjct: 312 VNADNVGS--KQMQQIRQGLRGKA---IVLMGKNTMMRKAI--RGHLDNNPGLEKLLPCI 470

Query: 236 -KEAGLKFSKGEILQIVNREDPNWWQASHVKEGGSAGL---IPSQ 276
               G  F++ +++++ +    N  QA   + G  A L   IP+Q
Sbjct: 471 KNNVGFVFTREDLVEVRDLLLANKVQAP-ARTGALAPLDVKIPAQ 602
>33804
          Length = 621

 Score = 29.3 bits (64), Expect = 4.7,   Method: Compositional matrix adjust.
 Identities = 11/52 (21%), Positives = 28/52 (53%)
 Frame = -1

Query: 483 SDLKKTVDESARIQRAYNHYFDLIIVNDNLDKAFEKLQTAIEKLRMEPQWVP 534
           S L+K  + + ++++ +  YF  ++  D +++ + K+++ I        WVP
Sbjct: 573 SRLRKHFERAIKMEQEFGEYFTGVVQGDTIEEIYSKVKSMIWSQSGPNIWVP 418
>28578
          Length = 408

 Score = 28.1 bits (61), Expect = 8.4,   Method: Composition-based stats.
 Identities = 15/37 (40%), Positives = 22/37 (59%)
 Frame = +3

Query: 482 DSDLKKTVDESARIQRAYNHYFDLIIVNDNLDKAFEK 518
           D+ +K  + + A I   +N Y  LII  D++ KAFEK
Sbjct: 249 DNTVKHRIMKRAIISMNHNKYIQLIIYLDSIFKAFEK 359
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|22726197|ref|NP_083732.1| SAPS domain family, member
3 [Mus musculus]
         (844 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

01080                                                                 238   1e-62
08991                                                                  29   7.5  
>01080
          Length = 1371

 Score =  238 bits (606), Expect = 1e-62,   Method: Compositional matrix adjust.
 Identities = 136/337 (40%), Positives = 205/337 (60%), Gaps = 42/337 (12%)
 Frame = +2

Query: 312 RLGSFH-------ELLLEPPKKS--VMKTTWGILDPPVGNTRLNVIRLISSLLQTNTSSI 362
           R GS+H       +L  +PPK+    M T+ G L+PP+GN RL V +LI++L+ TN + +
Sbjct: 236 RHGSYHTSLKKLPQLAYQPPKQRYCTMPTSVGSLEPPLGNARLQVTKLITALVATNMAPV 415

Query: 363 NGDLMELNSIGVILDMFFKYTWNNFLHTQVEICIALILASPFENAENGTITDQDSTGDNL 422
           N +L+ L+++  ++D++F+Y WNNFLHTQVE C+AL+L +P          + D   +  
Sbjct: 416 NLELVNLSTLQALMDLYFRYCWNNFLHTQVEQCVALVLNNP--------AVEVDGATEQP 571

Query: 423 LLKHLFQKCQLIERILEAWDTNEKKQA-EGGRRHGYMGHLTRIANCIVHSTDKGPNSALV 481
           LL+ LF   +L +R+LE W+ N+++Q+ EGG+R G+MGHLT++AN +  S D+G N  L+
Sbjct: 572 LLQQLFTDVRLPQRLLEEWEENDQQQSKEGGKRKGFMGHLTKMANALSGSKDRGCNCELI 751

Query: 482 QQLIKDLPDEVRERWETFCTNSLGETNKRNTVDL-------------------------- 515
           +    ++P+E R++W+ F   +L + NKRN V+                           
Sbjct: 752 KHFWAEVPEECRQKWDVFVLGTLADINKRNRVEFRGHPLASSSEDDDADFKDIPFPQDTA 931

Query: 516 ---AFSDYQMQQMTSNFIDQFGFNDEKFADQDDIGNVSF-DRVSDINFTLNTNE--SGNI 569
              AFSDYQ+QQMTSNFIDQFGFN+E+FA+Q++  +  F DR+S INF +  NE    N 
Sbjct: 932 MQQAFSDYQLQQMTSNFIDQFGFNEEEFAEQEEKIDAPFSDRISSINFNMQANEVTQPNN 1111

Query: 570 ALFEACCKERIQQFDDGGSDEEDIWEEKHIAFTPESQ 606
            +F+  C +RIQQFDD    +EDIW EK + F   +Q
Sbjct: 1112TMFDQACNDRIQQFDD-DDSDEDIWVEKPLTFDKNAQ 1219

 Score = 79.7 bits (195), Expect = 5e-15,   Method: Compositional matrix adjust.
 Identities = 44/104 (42%), Positives = 66/104 (63%)
 Frame = +3

Query: 225 QMLQVQNSTEPDPLLATLEKQEIIEQLLSNIFHKEKNESAIVSAIQILLTLLETRRPTFE 284
           QM+Q+Q++++PDPLLAT+E Q+ + ++LSN+F  E+NES IV+ + ++ TLLE RR   E
Sbjct: 3   QMMQLQDASDPDPLLATMEMQDTVSKMLSNMFELEQNESVIVNGLFVIHTLLEVRRQGQE 182

Query: 285 GHIEICPPGMSHSACSVNKSVLEAIRGRLGSFHELLLEPPKKSV 328
           G  E    G +        +V+ AI  RL +FH LL+ PP    
Sbjct: 183 GLNEQV--GDTDRLSQGITNVMAAIIPRLKNFHSLLINPPSNGT 308
>08991
          Length = 524

 Score = 29.3 bits (64), Expect = 7.5,   Method: Composition-based stats.
 Identities = 15/43 (34%), Positives = 21/43 (48%), Gaps = 1/43 (2%)
 Frame = +1

Query: 803 DAEETPE-PAEAKCTAPLTPSSSPEQRTDQPSMPSDPSVNGPV 844
           D  + P+ P++   +    PSSS   R   P+ PS P   GPV
Sbjct: 127 DXTQDPQDPSQGSASWVHPPSSSSLARPGSPAFPSFPGAGGPV 255
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|124248572|ref|NP_035822.2| von Hippel-Lindau binding
protein 1 [Mus musculus]
         (196 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

12824                                                                 234   2e-62
37035                                                                  34   0.034
28895                                                                  29   1.3  
19050                                                                  27   5.2  
>12824
          Length = 1493

 Score =  234 bits (597), Expect = 2e-62,   Method: Compositional matrix adjust.
 Identities = 108/172 (62%), Positives = 138/172 (80%)
 Frame = +2

Query: 23  GIPEAVFVEDVDSFMKQPGNETADTVLKKLDEQYQKYKFMELNLAQKKRRLKGQIPEIKQ 82
           GIP+  FVE VD FMK+P NE+A+ VL++ DE + KYKFME NL  KK RLK QIP+I+ 
Sbjct: 32  GIPQTDFVEAVDDFMKKPENESAEAVLRRFDELHSKYKFMEYNLNTKKTRLKSQIPDIRT 211

Query: 83  TLEILKYMQKKKESTNSMETRFLLADNLYCKASVPPTDKVCLWLGANVMLEYDIDEAQAL 142
           +L+I+K++Q KK+S++ +E+RFLL+D+L+ KA +PPTDKVCLWLGANVMLEY +D+A  L
Sbjct: 212 SLDIVKHLQSKKDSSDPLESRFLLSDHLFAKAKIPPTDKVCLWLGANVMLEYTLDDADDL 391

Query: 143 LEKNLSTATKNLDSLEEDLDFLRDQFTTTEVNMARVYNWDVKRRNKDDSTKN 194
           LEKNL TA K L  +E+DL FLRDQ TT EVNMARVYNWDVKRR  + + K+
Sbjct: 392 LEKNLGTAVKTLSQVEDDLGFLRDQMTTLEVNMARVYNWDVKRRQAEKAVKS 547
>37035
          Length = 531

 Score = 34.3 bits (77), Expect = 0.034,   Method: Compositional matrix adjust.
 Identities = 13/22 (59%), Positives = 18/22 (81%)
 Frame = +1

Query: 117 PPTDKVCLWLGANVMLEYDIDE 138
           PPT+++CLW  +NVML+YD  E
Sbjct: 463 PPTNRLCLW-SSNVMLDYDYCE 525
>28895
          Length = 1092

 Score = 28.9 bits (63), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 14/30 (46%), Positives = 16/30 (53%), Gaps = 1/30 (3%)
 Frame = +3

Query: 100 METRFLLADN-LYCKASVPPTDKVCLWLGA 128
           +ETR L  D  L C    PP D +C WLG 
Sbjct: 738 VETRNLXCDXCLMCGTHAPPYDLICGWLGV 827
>19050
          Length = 615

 Score = 26.9 bits (58), Expect = 5.2,   Method: Compositional matrix adjust.
 Identities = 14/60 (23%), Positives = 30/60 (50%), Gaps = 1/60 (1%)
 Frame = +3

Query: 68  QKKRRLKGQ-IPEIKQTLEILKYMQKKKESTNSMETRFLLADNLYCKASVPPTDKVCLWL 126
           Q+ RRL GQ + +++  + +   ++  +   ++    F L +     A +PP + +C WL
Sbjct: 276 QELRRLFGQTVGKVRDVVPVHLKLEHLRLDDDTQVEGFALVEGAQWLAVLPPHEPLCRWL 455
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31542956|ref|NP_058066.2| ubiquitin-conjugating
enzyme E2-25K [Mus musculus]
         (200 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

37111                                                                 234   2e-62
21443                                                                 114   2e-26
31099                                                                 105   2e-23
04905                                                                  86   7e-18
12485                                                                  86   1e-17
02313                                                                  79   1e-15
34525                                                                  76   7e-15
14380                                                                  76   1e-14
02740                                                                  70   6e-13
19311                                                                  68   2e-12
18592                                                                  68   3e-12
02183                                                                  63   8e-11
38163                                                                  56   8e-09
05633                                                                  55   2e-08
20166                                                                  54   3e-08
13254                                                                  41   2e-06
39424                                                                  44   3e-05
26740                                                                  39   0.001
10963                                                                  37   0.007
21913                                                                  31   0.33 
>37111
          Length = 611

 Score =  234 bits (597), Expect = 2e-62,   Method: Compositional matrix adjust.
 Identities = 109/167 (65%), Positives = 127/167 (76%)
 Frame = -1

Query: 1   MANIAVQRIKREFKEVLKSEETSKNQIKVDLVDENFTELRGEIAGPPDTPYEGGRYQLEI 60
           MANIA QRI+REFKEV+KS E ++  IKVD VD   T L+GEI GPP+TPYEGGR++L+I
Sbjct: 503 MANIAQQRIQREFKEVVKSAEVTQAAIKVDFVDGMLTHLKGEIMGPPETPYEGGRFELDI 324

Query: 61  KIPETYPFNPPKVRFITKIWHPNISSVTGAICLDILKDQWAAAMTLRTVXXXXXXXXXXX 120
           +IPETYPFNPP V+F+TKIWHPN+SSVTGAICLDILKDQWAAAMTLRTV           
Sbjct: 323 RIPETYPFNPPLVKFLTKIWHPNVSSVTGAICLDILKDQWAAAMTLRTVLLSLQALMAAA 144

Query: 121 EPDDPQDAVVANQYKQNPEMFKQTARLWAHVYAGAPVSSPEYTKKIE 167
           EPDDPQDAVVANQYK + E+F +TAR W   +A  P    E   K+ 
Sbjct: 143 EPDDPQDAVVANQYKDHRELFNKTARHWTSAFAQGPKREKEMEDKVH 3
>21443
          Length = 610

 Score =  114 bits (286), Expect = 2e-26,   Method: Compositional matrix adjust.
 Identities = 59/150 (39%), Positives = 85/150 (56%)
 Frame = -1

Query: 4   IAVQRIKREFKEVLKSEETSKNQIKVDLVDENFTELRGEIAGPPDTPYEGGRYQLEIKIP 63
           +A++RI +E +++ K       Q     V E+  + +  I GP D+ YEGG + L I  P
Sbjct: 535 MAMKRINKELQDLGKDPPA---QCSAGPVGEDMFQWQATIMGPRDSAYEGGVFFLTISFP 365

Query: 64  ETYPFNPPKVRFITKIWHPNISSVTGAICLDILKDQWAAAMTLRTVXXXXXXXXXXXEPD 123
             YPF PPKV F T+I+HPNI+S  G+ICLDIL+ QW+ A+T+  V            PD
Sbjct: 364 TDYPFKPPKVSFTTRIYHPNINS-NGSICLDILRSQWSPALTISKVLLSICSMLTDPNPD 188

Query: 124 DPQDAVVANQYKQNPEMFKQTARLWAHVYA 153
           DP    +A  YK + E F + A++W + YA
Sbjct: 187 DPLVPEIARIYKTDREKFYENAKIWTNKYA 98
>31099
          Length = 748

 Score =  105 bits (261), Expect = 2e-23,   Method: Compositional matrix adjust.
 Identities = 51/122 (41%), Positives = 69/122 (56%)
 Frame = +2

Query: 32  VDENFTELRGEIAGPPDTPYEGGRYQLEIKIPETYPFNPPKVRFITKIWHPNISSVTGAI 91
           V ++F   +  I GP  +PY+GG + L I  P  YPF PPKV F TKI+HPNI+S  G+I
Sbjct: 167 VGDDFFHWQATIMGPNKSPYQGGVFFLTITFPADYPFKPPKVAFTTKIYHPNINS-NGSI 343

Query: 92  CLDILKDQWAAAMTLRTVXXXXXXXXXXXEPDDPQDAVVANQYKQNPEMFKQTARLWAHV 151
           CLDIL+ QW+ A+T+  V            PDDP    +A  YK +   ++Q  + W   
Sbjct: 344 CLDILRSQWSPALTISKVLLSISSLLTDPNPDDPLVPEIARVYKNDRHKYEQLGKEWTQK 523

Query: 152 YA 153
           YA
Sbjct: 524 YA 529
>04905
          Length = 1868

 Score = 86.3 bits (212), Expect = 7e-18,   Method: Compositional matrix adjust.
 Identities = 39/120 (32%), Positives = 59/120 (49%), Gaps = 1/120 (0%)
 Frame = -1

Query: 35   NFTELRGEIAGPPDTPYEGGRYQLEIKIPETYPFNPPKVRFITKIWHPNISSVTGAICLD 94
               E   +  GPP TPYEGG +++ + +PE YPF  P + FI +I+HPNI  V+G +CLD
Sbjct: 1694 GLNEFTVKFFGPPSTPYEGGVWKVRVDLPERYPFKSPSIGFINRIYHPNIDEVSGTVCLD 1515

Query: 95   ILKDQWAAAMTLRTVXXXXX-XXXXXXEPDDPQDAVVANQYKQNPEMFKQTARLWAHVYA 153
            ++   W A   L  +             P DP +   A  Y   P+ +K+    +   +A
Sbjct: 1514 VINQAWTALYDLSNIFESFLPQLLTYPNPVDPLNGDAAALYLHRPDEYKKKVEEYVQKFA 1335
>12485
          Length = 652

 Score = 85.5 bits (210), Expect = 1e-17,   Method: Compositional matrix adjust.
 Identities = 41/119 (34%), Positives = 61/119 (51%), Gaps = 2/119 (1%)
 Frame = +1

Query: 35  NFTELRGEIAGPPDTPYEGGRYQLEIKIPETYPFNPPKVRFITKIWHPNISSVTGAICLD 94
              E   +  GPP TPYEGG +++ + +PE YPF  P + F+ +I+HPNI  V+G +CLD
Sbjct: 1   GLNEFLVKFYGPPSTPYEGGVWKVRVDLPEKYPFKSPSIGFMNRIYHPNIDEVSGTVCLD 180

Query: 95  ILKDQWAAAMTLRTVXXXXX-XXXXXXEPDDPQDAVVANQYKQNPEMF-KQTARLWAHV 151
           ++   W A   L  +             P DP +   A  Y   PE + K+++RL   V
Sbjct: 181 VINQAWTALYDLSNIFESFLPQLLTYPNPIDPLNGDAAALYLHKPEDYKKKSSRLCTEV 357
>02313
          Length = 891

 Score = 79.3 bits (194), Expect = 1e-15,   Method: Compositional matrix adjust.
 Identities = 43/121 (35%), Positives = 68/121 (56%), Gaps = 13/121 (10%)
 Frame = -1

Query: 2   ANIAVQRIKREFKEVLKSEETSKNQIKVDLVDENFTELRGEIAGPPDTPYEGGRYQLEIK 61
           A  AV+ ++ E K++ ++E     ++K+ + D+N  E    I GPP T YEGG ++  +K
Sbjct: 774 AGGAVKALQLELKKI-QAEPVEGFRVKL-INDDNIFEWEVAIFGPPGTLYEGGYFKAHMK 601

Query: 62  IPETYPFNPPKVRFITKIWHPNISSVTGAICLDILK-------------DQWAAAMTLRT 108
            P  YP++PP VRFITK+WHPN+    G +C+ IL              ++W    T+RT
Sbjct: 600 FPADYPYSPPSVRFITKMWHPNVYE-NGEVCISILHPPVDDPQSGELPSERWNPTQTVRT 424

Query: 109 V 109
           +
Sbjct: 423 I 421
>34525
          Length = 561

 Score = 76.3 bits (186), Expect = 7e-15,   Method: Compositional matrix adjust.
 Identities = 42/107 (39%), Positives = 56/107 (52%), Gaps = 4/107 (3%)
 Frame = -1

Query: 59  EIKIPETYPFNPPKVRFITKIWHPNISSVTGAICLDIL----KDQWAAAMTLRTVXXXXX 114
            + +PE YPF PPKV+F T I+HPNI +  G ICLD L    K  W   M L TV     
Sbjct: 381 HLILPERYPFEPPKVQFTTPIYHPNIDNA-GRICLDTLKMPPKGAWKPCMNLMTVLTSLQ 205

Query: 115 XXXXXXEPDDPQDAVVANQYKQNPEMFKQTARLWAHVYAGAPVSSPE 161
                  PDD   A +A+++K  PE+F+Q A  +   +A   V  P+
Sbjct: 204 LLMATPNPDDALMADIASEFKHTPELFRQKAVQFTKQHAYDSVLQPQ 64
>14380
          Length = 1522

 Score = 75.9 bits (185), Expect = 1e-14,   Method: Compositional matrix adjust.
 Identities = 35/126 (27%), Positives = 67/126 (53%)
 Frame = +3

Query: 28  KVDLVDENFTELRGEIAGPPDTPYEGGRYQLEIKIPETYPFNPPKVRFITKIWHPNISSV 87
           K+   DE+ T+++  I GP  TPY GG +++++ + +++P  PPK  FITKI+HPN++S 
Sbjct: 174 KIFTNDEDITDIQATIEGPAGTPYAGGLFRMKLVLSKSFPSEPPKAFFITKIFHPNVAS- 350

Query: 88  TGAICLDILKDQWAAAMTLRTVXXXXXXXXXXXEPDDPQDAVVANQYKQNPEMFKQTARL 147
            G IC++ LK  W   + ++ +            P+   +        +  E +   A++
Sbjct: 351 NGEICVNTLKRDWKPELGIKHILLTVKCLLIVPNPESALNEEAGKLLLEQYEDYSMRAKM 530

Query: 148 WAHVYA 153
           +  ++A
Sbjct: 531 FTEIHA 548
>02740
          Length = 2287

 Score = 70.1 bits (170), Expect = 6e-13,   Method: Compositional matrix adjust.
 Identities = 36/103 (34%), Positives = 59/103 (57%)
 Frame = -1

Query: 7    QRIKREFKEVLKSEETSKNQIKVDLVDENFTELRGEIAGPPDTPYEGGRYQLEIKIPETY 66
            +R+++E + ++ S +     +      +N  +  G I G   T YEG +Y+L ++ P  Y
Sbjct: 1996 KRLQQELRTLMMSSDPG---VSAFPDGDNLFKWVGTIEGAKGTVYEGLQYKLVLEFPSGY 1826

Query: 67   PFNPPKVRFITKIWHPNISSVTGAICLDILKDQWAAAMTLRTV 109
            P+    VRF T  +HPN+ +  G ICLDILK++W+A   +RTV
Sbjct: 1825 PYQAVSVRFSTPCFHPNVDN-HGNICLDILKEKWSALYDVRTV 1700
>19311
          Length = 1071

 Score = 68.2 bits (165), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 38/109 (34%), Positives = 55/109 (50%)
 Frame = -2

Query: 45  GPPDTPYEGGRYQLEIKIPETYPFNPPKVRFITKIWHPNISSVTGAICLDILKDQWAAAM 104
           GP     +GG + L ++IP +YP  PPKVRFITKI+HPNIS   G + LD +   W+ A+
Sbjct: 485 GPRAVRXKGGWFLLYLQIPHSYPMRPPKVRFITKIFHPNISR-HGDVGLDSIHHNWSLAL 309

Query: 105 TLRTVXXXXXXXXXXXEPDDPQDAVVANQYKQNPEMFKQTARLWAHVYA 153
           T+  V                 +  +   Y++    F++ AR W   YA
Sbjct: 308 TISKVLISIQSVLTDPYCHVCMEPKIGALYQRAKPEFERIARRWTWKYA 162
>18592
          Length = 475

 Score = 67.8 bits (164), Expect = 3e-12,   Method: Compositional matrix adjust.
 Identities = 41/131 (31%), Positives = 64/131 (48%), Gaps = 1/131 (0%)
 Frame = +2

Query: 5   AVQRIKREFKEVLKSEETSKNQIKVDLVDENFTELRGEIAGPPDTPYEGGRYQLEIKIPE 64
           A +R+ +E +++ K  E S+   ++   DE+       +  P + PY  G + ++I  P 
Sbjct: 92  ATRRLTKELQDIRK--EASQKAFRIKDQDESNILHWEVVLVPENPPYNKGTFTVDINFPA 265

Query: 65  TYPFNPPKVRFITKIWHPNISSVTGAICLDILK-DQWAAAMTLRTVXXXXXXXXXXXEPD 123
            YPF PPKV F TKI+HPN+    G +CL I+  + W  A     V           EP+
Sbjct: 266 EYPFKPPKVTFKTKIYHPNVDE-KGQVCLPIISAENWKPATKTDQVLTALIGLINEPEPE 442

Query: 124 DPQDAVVANQY 134
            P  A +A +Y
Sbjct: 443 HPLRADLAEEY 475
>02183
          Length = 1456

 Score = 62.8 bits (151), Expect = 8e-11,   Method: Compositional matrix adjust.
 Identities = 46/153 (30%), Positives = 65/153 (42%), Gaps = 7/153 (4%)
 Frame = -2

Query: 8    RIKREFKEVLKSEETSKNQIKVDLVDENFTELRGEIAGPPDTPYEGGRYQLEIKIPETYP 67
            R K   KEV + EE      KV   D +          P +  + GG+++ +I +PE Y 
Sbjct: 1290 RDKLLVKEVQEMEENMPRTCKVQFDDPSVLHHFILNVTPDEGYWTGGKFKFDINVPEEYN 1111

Query: 68   FNPPKVRFITKIWHPNISSVTGAICLDILKDQ------WAAAMTLRTVX-XXXXXXXXXX 120
              PPK    TKIWHPNI+   G ICL +L+        WA    L+ V            
Sbjct: 1110 IVPPKAVCHTKIWHPNITE-AGEICLSLLRQNSYDGLGWAPTRRLKDVVWGLNSLFSDLL 934

Query: 121  EPDDPQDAVVANQYKQNPEMFKQTARLWAHVYA 153
              +DP +   A  + ++ E FK   R +   YA
Sbjct: 933  NFEDPLNVEAAEHFARDKESFKIKVRDYIQAYA 835
>38163
          Length = 2214

 Score = 56.2 bits (134), Expect = 8e-09,   Method: Compositional matrix adjust.
 Identities = 32/114 (28%), Positives = 52/114 (45%), Gaps = 2/114 (1%)
 Frame = -3

Query: 35   NFTELRGEIAGPPDTPYEGGRYQLEIKIPETYPFNPPKVRFITKIWHPNISSVTGAICLD 94
            N      +I G   T +EGG + L +   E YP  PPK +F   ++HPN+   +G +CL 
Sbjct: 1678 NLFNWECKIPGKKGTMWEGGLFSLRMLFKEDYPSTPPKCKFEPPLFHPNVYP-SGTVCLS 1502

Query: 95   ILKDQ--WAAAMTLRTVXXXXXXXXXXXEPDDPQDAVVANQYKQNPEMFKQTAR 146
            +L ++  W  A+T++ +              DP  A     Y QN   +++  R
Sbjct: 1501 LLDEEKDWRPAVTIKQILLGIQELLNECNVKDPAQAEAYTIYCQNSSEYERRVR 1340
>05633
          Length = 1150

 Score = 54.7 bits (130), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 33/113 (29%), Positives = 54/113 (47%), Gaps = 4/113 (3%)
 Frame = +3

Query: 42  EIAGPPDTPYEGGRYQLEIKIPETYPFNPPKVRFITK--IWHPNISSVTGAICLDILKDQ 99
           ++ G   T YEG ++QL  K    YPF+ P+V F+      HP++ S  G ICL IL + 
Sbjct: 54  DLEGATGTLYEGEKFQLHFKFGAKYPFDSPQVTFLGPNIPIHPHVYS-NGHICLSILTED 230

Query: 100 WAAAMTLRTVXXX--XXXXXXXXEPDDPQDAVVANQYKQNPEMFKQTARLWAH 150
           W+ A+++++V             +   P +A+      +NP    +  R W H
Sbjct: 231 WSPALSVQSVCLSIVSMLSSCTEKKRPPDNAIYVKTCSKNP----KKTRWWYH 377
>20166
          Length = 446

 Score = 54.3 bits (129), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 34/81 (41%), Positives = 43/81 (53%), Gaps = 4/81 (4%)
 Frame = +1

Query: 33  DENFTELRGEIAGPPDTPYEGGRYQLEIKIPETYPFNPPKVRFITKIWHPNISSV--TGA 90
           D N    +G I GP  TPYEG  Y L +  P +YP +PP VRF TKI   N+S V   G 
Sbjct: 37  DRNLESWQGTIIGPMKTPYEGRIYTLRMSCPMSYPRHPPSVRFETKI---NLSCVEDNGT 207

Query: 91  ICLDIL--KDQWAAAMTLRTV 109
           + L  L  K  W +  TL+ +
Sbjct: 208 VDLKRLGRKFAWDSNTTLKVI 270
>13254
          Length = 870

 Score = 41.2 bits (95), Expect(2) = 2e-06,   Method: Compositional matrix adjust.
 Identities = 21/85 (24%), Positives = 39/85 (45%)
 Frame = +2

Query: 69  NPPKVRFITKIWHPNISSVTGAICLDILKDQWAAAMTLRTVXXXXXXXXXXXEPDDPQDA 128
           N  K  F+TKI+HPN++S  G IC++ LK  W   + ++ +            P+   + 
Sbjct: 164 NAAKGIFLTKIFHPNVAS-NGEICVNTLKKDWKPDLGIKHILLTIKCLLIVPNPESALNE 340

Query: 129 VVANQYKQNPEMFKQTARLWAHVYA 153
                  +  + + Q AR+   ++A
Sbjct: 341 EAGKMLLERYDDYSQRARMMTEIHA 415

 Score = 26.2 bits (56), Expect(2) = 2e-06,   Method: Compositional matrix adjust.
 Identities = 11/40 (27%), Positives = 25/40 (62%)
 Frame = +1

Query: 27 IKVDLVDENFTELRGEIAGPPDTPYEGGRYQLEIKIPETY 66
          IKV + + + T+++  I GP  TPY  G +++++ + + +
Sbjct: 40 IKVIINESDVTDVQALIDGPAGTPYAVGIFRVKLTLSKDF 159
>39424
          Length = 1749

 Score = 44.3 bits (103), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 23/94 (24%), Positives = 42/94 (44%), Gaps = 13/94 (13%)
 Frame = -2

Query: 63   PETYPFNPPKVRFITKIWHPNISSVTGAICLDILK-------------DQWAAAMTLRTV 109
            P+  P   PK++F++++WHPNI    G +C+ IL              ++W    T+ T+
Sbjct: 1514 PKNIPIGRPKMKFVSEMWHPNIDP-EGNVCISILHEPGDDKYGYEKASERWLPIHTVETI 1338

Query: 110  XXXXXXXXXXXEPDDPQDAVVANQYKQNPEMFKQ 143
                         + P +   A  +++ PE FK+
Sbjct: 1337 LVSVISMLADPNDESPANVDAAKMWREQPEEFKK 1236

 Score = 35.0 bits (79), Expect = 0.020,   Method: Compositional matrix adjust.
 Identities = 18/64 (28%), Positives = 35/64 (54%)
 Frame = -1

Query: 9    IKREFKEVLKSEETSKNQIKVDLVDENFTELRGEIAGPPDTPYEGGRYQLEIKIPETYPF 68
            ++++  E+ KS     +   +D  D++  +    I GPP+T ++GG ++  +  P+ YP 
Sbjct: 1671 LRKQLAELSKSGTEGFSAGLID--DDDVYKWEVLIYGPPETLFDGGYFKAHLIFPKEYPN 1498

Query: 69   NPPK 72
             PPK
Sbjct: 1497 RPPK 1486
>26740
          Length = 404

 Score = 38.9 bits (89), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 21/67 (31%), Positives = 34/67 (50%), Gaps = 1/67 (1%)
 Frame = +2

Query: 6   VQRIKREFKEVLKSEETSKNQ-IKVDLVDENFTELRGEIAGPPDTPYEGGRYQLEIKIPE 64
            +R+ +E   +  S   S N  + V   DE    ++  I GP DTPY  G ++ ++  P+
Sbjct: 191 TRRLAQEAVTLSTSLPLSYNSSVFVRCDDERLDIMKVLITGPSDTPYANGAFEFDVYFPQ 370

Query: 65  TYPFNPP 71
            YP +PP
Sbjct: 371 DYPNSPP 391
>10963
          Length = 569

 Score = 36.6 bits (83), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 18/31 (58%), Positives = 23/31 (74%)
 Frame = +3

Query: 68  FNPPKVRFITKIWHPNISSVTGAICLDILKD 98
           F   +V F T+I+H NI+S  GAICLDILK+
Sbjct: 474 FANVQVVFKTRIYHCNINS-QGAICLDILKE 563
>21913
          Length = 874

 Score = 30.8 bits (68), Expect = 0.33,   Method: Compositional matrix adjust.
 Identities = 23/95 (24%), Positives = 41/95 (43%), Gaps = 2/95 (2%)
 Frame = +3

Query: 51  YEGGRYQLEIKIPETYP-FNPPKVRFITKIWHPNISSVTGAICLDILKDQWAAAMT-LRT 108
           YEG   +  + IP+ YP  + P + F   ++HP +  V+G + +     +W   +  L  
Sbjct: 153 YEGCSLRFTLTIPDNYPDGDCPDLVFEFPVFHPLVDPVSGKVDVKRAFPKWRRNVNHLWQ 332

Query: 109 VXXXXXXXXXXXEPDDPQDAVVANQYKQNPEMFKQ 143
           V           E   P +   A  Y+Q+ + F+Q
Sbjct: 333 VLMYARKIFYKIETKAPLNPEAATLYEQDTDQFRQ 437
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6679447|ref|NP_032941.1| protein phosphatase 3,
catalytic subunit, gamma isoform [Mus musculus]
         (513 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

17953                                                                 155   2e-62
01173                                                                 218   3e-57
06264                                                                 216   2e-56
08242                                                                 212   2e-55
06084                                                                 177   1e-44
19040                                                                 154   8e-38
25536                                                                 120   2e-27
18336                                                                 100   2e-22
36367                                                                  69   6e-12
04295                                                                  45   8e-05
21146                                                                  39   0.007
30980                                                                  34   0.15 
>17953
          Length = 626

 Score =  155 bits (393), Expect(2) = 2e-62,   Method: Compositional matrix adjust.
 Identities = 80/143 (55%), Positives = 94/143 (65%), Gaps = 2/143 (1%)
 Frame = -3

Query: 327 IRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVTEMLVNILNICSDEEMNVTDEEGA--TTG 384
           I +FNCSPHPYWLPNFMDVFTWSLPFVGEKVTEMLVNILNICSD+E+    ++ A     
Sbjct: 483 IIKFNCSPHPYWLPNFMDVFTWSLPFVGEKVTEMLVNILNICSDDELVTEGDDSAAEVAA 304

Query: 385 RKEVIKNKIRAIGKMARVFTVLREESENXXXXXXXXXXXXXXXXXXXXXKQTIETAKQEA 444
           RKEVI+NKIRAIGKMARVFTVLREESE+                     K T+ +     
Sbjct: 303 RKEVIRNKIRAIGKMARVFTVLREESESVLQLKGLTPNGLLPLGALSGGKDTLTS----- 139

Query: 445 AEEREAIRGFTIAHRIRSFEEAR 467
                A+ GF+ +H+I  FEE +
Sbjct: 138 -----ALSGFSPSHKISGFEEDK 85

 Score =  102 bits (253), Expect(2) = 2e-62,   Method: Compositional matrix adjust.
 Identities = 47/55 (85%), Positives = 50/55 (90%)
 Frame = -2

Query: 265 LQNNSLLSIIRAHEAQDAGYRMYRKNQATGFPSLITIFSAPNYLDVYNNKAAVLK 319
           LQ N+LLSIIRAHEAQDAGYRMYRK+Q TGFPSLITIFSAPNYLDVYNNK  +L 
Sbjct: 625 LQQNNLLSIIRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKVQLLS 461

 Score = 28.1 bits (61), Expect = 8.3,   Method: Compositional matrix adjust.
 Identities = 14/31 (45%), Positives = 21/31 (67%), Gaps = 2/31 (6%)
 Frame = -2

Query: 454 FTIAH--RIRSFEEARGLDRINERMPPRKEA 482
            T+A   RIR  + A   +++NERMPPRK++
Sbjct: 124 LTVAQDQRIRGRQNA--WNKMNERMPPRKDS 38
>01173
          Length = 2619

 Score =  218 bits (556), Expect = 3e-57,   Method: Compositional matrix adjust.
 Identities = 104/259 (40%), Positives = 160/259 (61%)
 Frame = -1

Query: 67   ILKQEKTMIEVEAPITVCGDVHGQFFDLMKLFEVGGSPSNTRYLFLGDYVDRGYFSIECV 126
            I   +  ++E+EAP+ +CGD+HGQ++DL++LFE GG P  + YLFLGDYVDRG  S+E +
Sbjct: 2562 IFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETI 2383

Query: 127  LYLWSLKINHPKTLFLLRGNHECRHLTEYFTFKQECRIKYSEMVYDACMHTFDCLPLAAL 186
              L + KI +P+  FLLRGNHEC  +   + F  EC+ +Y+  ++      F+CLP+AA+
Sbjct: 2382 CLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAI 2203

Query: 187  LNQQFLCVHGGMSPEITCLEDIRKLDRFSEPPAFGPVCDLLWSDPLEDYGSEKTLEHYTH 246
            ++++  C HGG+SP++  +E IR++ R ++ P  G +CDLLWSDP      +K    +  
Sbjct: 2202 IDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDP------DKETMGWGE 2041

Query: 247  NTVRGCSYFFSYPAVCEFLQNNSLLSIIRAHEAQDAGYRMYRKNQATGFPSLITIFSAPN 306
            N  RG S+ F    V +FL  + L  I RAH+  + GY  + K Q      L+T+FSAPN
Sbjct: 2040 ND-RGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQ------LVTLFSAPN 1882

Query: 307  YLDVYNNKAAVLKYENNVM 325
            Y   ++N  A++  +  +M
Sbjct: 1881 YCGEFDNAGAMMSVDETLM 1825
>06264
          Length = 999

 Score =  216 bits (550), Expect = 2e-56,   Method: Compositional matrix adjust.
 Identities = 103/259 (39%), Positives = 160/259 (61%)
 Frame = -3

Query: 67  ILKQEKTMIEVEAPITVCGDVHGQFFDLMKLFEVGGSPSNTRYLFLGDYVDRGYFSIECV 126
           I   +  ++E+EAP+ +CGD+HGQ++DL++LFE GG P  + YLFLGDYVDRG  S+E +
Sbjct: 964 IFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGRQSLETI 785

Query: 127 LYLWSLKINHPKTLFLLRGNHECRHLTEYFTFKQECRIKYSEMVYDACMHTFDCLPLAAL 186
             L + KI +P+  FLLRGNHEC  +   + F  EC+ +Y+  ++      F+CLP+AA+
Sbjct: 784 CLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAI 605

Query: 187 LNQQFLCVHGGMSPEITCLEDIRKLDRFSEPPAFGPVCDLLWSDPLEDYGSEKTLEHYTH 246
           ++++  C HGG+SP++  +E IR++ R ++ P  G +CDLLWSDP      +K    +  
Sbjct: 604 IDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDP------DKETMGWGE 443

Query: 247 NTVRGCSYFFSYPAVCEFLQNNSLLSIIRAHEAQDAGYRMYRKNQATGFPSLITIFSAPN 306
           +  RG S+ F    V +FL  + L  I RAH+  + GY  + K Q      L+T+FSAPN
Sbjct: 442 SD-RGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQ------LVTLFSAPN 284

Query: 307 YLDVYNNKAAVLKYENNVM 325
           Y   ++N  A++  +  +M
Sbjct: 283 YCGEFDNAGAMMSVDETLM 227
>08242
          Length = 3368

 Score =  212 bits (540), Expect = 2e-55,   Method: Compositional matrix adjust.
 Identities = 107/261 (40%), Positives = 159/261 (60%), Gaps = 3/261 (1%)
 Frame = -1

Query: 67   ILKQEKTMIEVEAPITVCGDVHGQFFDLMKLFEVGGSPSNTRYLFLGDYVDRGYFSIECV 126
            IL +E  +  V++P+TVCGD+HGQF+DL +LF+VGG   +T YLF+GD+VDRG++S+E  
Sbjct: 3365 ILVEESNVQRVDSPVTVCGDIHGQFYDLKELFKVGGDVPDTNYLFMGDFVDRGFYSVETF 3186

Query: 127  LYLWSLKINHPKTLFLLRGNHECRHLTEYFTFKQECRIKYSEM-VYDACMHTFDCLPLAA 185
            L L +LK+ +P  + L+RGNHE R +T+ + F  EC  KY  + V+  C   FD L L+A
Sbjct: 3185 LLLLALKVRYPDRITLIRGNHESRQITQVYGFYDECLRKYGSITVWRYCTEIFDYLSLSA 3006

Query: 186  LLNQQFLCVHGGMSPEITCLEDIRKLDRFSEPPAFGPVCDLLWSDP--LEDYGSEKTLEH 243
            +++ +  CVHGG+SP I  L+ IR +DR  E P  GP+CDLLWSDP  ++ +G       
Sbjct: 3005 IIDGKIFCVHGGLSPSIQTLDQIRSIDRKQEVPHDGPMCDLLWSDPEDMQGWGVSP---- 2838

Query: 244  YTHNTVRGCSYFFSYPAVCEFLQNNSLLSIIRAHEAQDAGYRMYRKNQATGFPSLITIFS 303
                  RG  Y F    V +F   N +  I RAH+    GY+ +         +++T++S
Sbjct: 2837 ------RGAGYLFGSDVVSQFNAANXIDLICRAHQLVMEGYKWHFNE------TVLTVWS 2694

Query: 304  APNYLDVYNNKAAVLKYENNV 324
            APNY     N AA+L+ + ++
Sbjct: 2693 APNYCYRCGNVAAILELDEHL 2631
>06084
          Length = 1739

 Score =  177 bits (449), Expect = 1e-44,   Method: Compositional matrix adjust.
 Identities = 97/236 (41%), Positives = 138/236 (58%), Gaps = 1/236 (0%)
 Frame = -2

Query: 88   HGQFFDLMKLFEVGGSPSNTRYLFLGDYVDRGYFSIECVLYLWSLKINHPKTLFLLRGNH 147
            HGQF+DLM+LF+ GG   +T Y+F+GD+VDRGYFS+E    L +LK   P  + LLRGNH
Sbjct: 1738 HGQFYDLMELFKTGGEMPDTNYVFMGDFVDRGYFSLETFTLLLTLKAKWPDKIVLLRGNH 1559

Query: 148  ECRHLTEYFTFKQECRIKYSEM-VYDACMHTFDCLPLAALLNQQFLCVHGGMSPEITCLE 206
            E R +T+ + F  EC+ KY     +  C   FD L +AA++++  LCVHGG+SP+I  ++
Sbjct: 1558 ESRQITQIYGFYDECQTKYGNANAWRYCCRVFDLLTIAAIIDECILCVHGGLSPDIKTID 1379

Query: 207  DIRKLDRFSEPPAFGPVCDLLWSDPLEDYGSEKTLEHYTHNTVRGCSYFFSYPAVCEFLQ 266
             IR ++R  E P  G  CDL+WSDP ED  +          + RG  + F      EF+ 
Sbjct: 1378 QIRTIERNQEIPHKGAFCDLVWSDP-EDVDTWAM-------SPRGAGWLFGAKVTAEFVA 1223

Query: 267  NNSLLSIIRAHEAQDAGYRMYRKNQATGFPSLITIFSAPNYLDVYNNKAAVLKYEN 322
            +N+L  I RAH+    GY+     +      L+T++SAPNY     N AAVL + +
Sbjct: 1222 SNNLKLICRAHQLVHEGYKYMFDEK------LVTVWSAPNYCYRCGNIAAVLSFTD 1073
>19040
          Length = 452

 Score =  154 bits (389), Expect = 8e-38,   Method: Composition-based stats.
 Identities = 63/140 (45%), Positives = 96/140 (68%)
 Frame = -3

Query: 67  ILKQEKTMIEVEAPITVCGDVHGQFFDLMKLFEVGGSPSNTRYLFLGDYVDRGYFSIECV 126
           I  Q+  ++E+EAP+ +CGD+HGQ+ DL++LFE GG P    YLFLGDYVDRG  S+E +
Sbjct: 423 IFLQQPILLELEAPLIICGDIHGQYTDLLRLFEYGGFPPAANYLFLGDYVDRGKQSLETI 244

Query: 127 LYLWSLKINHPKTLFLLRGNHECRHLTEYFTFKQECRIKYSEMVYDACMHTFDCLPLAAL 186
             L + KI +P+  FLLRGNHEC  +   + F  EC+ +Y+  ++      F+CLP+AA+
Sbjct: 243 CLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNVKLWKTFTDCFNCLPVAAI 64

Query: 187 LNQQFLCVHGGMSPEITCLE 206
           ++++  C HGG+SP++  +E
Sbjct: 63  IDEKIFCCHGGLSPDLQGME 4
>25536
          Length = 486

 Score =  120 bits (300), Expect = 2e-27,   Method: Compositional matrix adjust.
 Identities = 54/101 (53%), Positives = 71/101 (70%)
 Frame = +1

Query: 67  ILKQEKTMIEVEAPITVCGDVHGQFFDLMKLFEVGGSPSNTRYLFLGDYVDRGYFSIECV 126
           IL +E  + EV+ P+TVCGDVHGQF DLM+LF +GG   +T YLF+GDYVDRGY+S+E V
Sbjct: 154 ILSKESNVQEVKCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETV 333

Query: 127 LYLWSLKINHPKTLFLLRGNHECRHLTEYFTFKQECRIKYS 167
             L +LK+     + +LRGNHE R +T+ + F  EC  KY 
Sbjct: 334 SLLVALKVRFRDRITILRGNHESRQITQVYGFYDECLRKYG 456
>18336
          Length = 465

 Score =  100 bits (250), Expect(2) = 2e-22,   Method: Composition-based stats.
 Identities = 41/76 (53%), Positives = 55/76 (72%)
 Frame = +2

Query: 83  VCGDVHGQFFDLMKLFEVGGSPSNTRYLFLGDYVDRGYFSIECVLYLWSLKINHPKTLFL 142
           +CGD+HGQ++DL++LFE GG P  + YLFLGDYVDRG  S+E +  L + KI +P+  FL
Sbjct: 104 ICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFL 283

Query: 143 LRGNHECRHLTEYFTF 158
           LRGNHEC  +   + F
Sbjct: 284 LRGNHECASINRIYGF 331

 Score = 23.1 bits (48), Expect(2) = 2e-22,   Method: Compositional matrix adjust.
 Identities = 7/11 (63%), Positives = 10/11 (90%)
 Frame = +3

Query: 192 LCVHGGMSPEI 202
           LC HGG+SP++
Sbjct: 429 LCCHGGLSPDL 461

 Score = 28.9 bits (63), Expect = 5.1,   Method: Composition-based stats.
 Identities = 18/69 (26%), Positives = 36/69 (52%), Gaps = 1/69 (1%)
 Frame = +1

Query: 127 LYLWSLKINHPKTLFLL-RGNHECRHLTEYFTFKQECRIKYSEMVYDACMHTFDCLPLAA 185
           ++ +SL+   P+ LFL  R    C +      +  EC+ +Y+  ++      F+CLP+AA
Sbjct: 235 MFTFSLQN*IPRKLFLTTRKPRMCVYQ*NLRVY-DECKRRYNIKLWKTFTDCFNCLPIAA 411

Query: 186 LLNQQFLCV 194
           +++ +   V
Sbjct: 412 IIDVKIFVV 438
>36367
          Length = 827

 Score = 68.6 bits (166), Expect = 6e-12,   Method: Compositional matrix adjust.
 Identities = 55/155 (35%), Positives = 81/155 (52%), Gaps = 13/155 (8%)
 Frame = +1

Query: 195 HGGM-SPEITC---LEDIRKLD-RFSEPPAFGPVC-DLLWSDPLE-DYGSEKTL----EH 243
           HGG+ SPE      LE I K+    S+P    P+  ++LWSDP+  D  S + L    EH
Sbjct: 1   HGGIPSPENEGGGHLEAINKIPVPLSDPEVDSPMAWEILWSDPISVDLVSPEVLKDMKEH 180

Query: 244 --YTHNTVRGCSYFFSYPAVCEFLQNNSLLSIIRAHEAQDAGYRMYRKNQATGFPSLITI 301
             +T N+ RG ++FFS  A+  FL+ N L  +IRAHE Q+ G+++ ++ +      L+T+
Sbjct: 181 HGFTFNSRRGTAHFFSCNALLAFLERNGLSHVIRAHEVQEVGFQVQQQGK------LLTV 342

Query: 302 FSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHP 336
           FS+  Y    N  A VL     +  IR     P P
Sbjct: 343 FSSSRYCGGSNEAACVLADNYKLRMIRIDTT*PGP 447
>04295
          Length = 748

 Score = 45.1 bits (105), Expect = 8e-05,   Method: Compositional matrix adjust.
 Identities = 22/65 (33%), Positives = 35/65 (53%)
 Frame = -1

Query: 261 VCEFLQNNSLLSIIRAHEAQDAGYRMYRKNQATGFPSLITIFSAPNYLDVYNNKAAVLKY 320
           V +FL  + L  I RAH+  + GY  + K Q      L+T+FSAPNY   ++N   ++  
Sbjct: 739 VSKFLNRHDLDLITRAHQVVEDGYEFFAKRQ------LVTLFSAPNYCGEFDNAGGMMSV 578

Query: 321 ENNVM 325
           +  +M
Sbjct: 577 DETLM 563
>21146
          Length = 408

 Score = 38.5 bits (88), Expect = 0.007,   Method: Composition-based stats.
 Identities = 23/58 (39%), Positives = 28/58 (48%)
 Frame = +3

Query: 221 GPVCDLLWSDPLEDYGSEKTLEHYTHNTVRGCSYFFSYPAVCEFLQNNSLLSIIRAHE 278
           GP+CDLLWSDP +D G           + RG  Y F       F  +N L  I RAH+
Sbjct: 117 GPMCDLLWSDP-DDRGGWGI-------SPRGAGYTFGQDISETFNHSNGLTLISRAHQ 266
>30980
          Length = 765

 Score = 33.9 bits (76), Expect = 0.15,   Method: Compositional matrix adjust.
 Identities = 23/72 (31%), Positives = 38/72 (52%), Gaps = 1/72 (1%)
 Frame = +3

Query: 264 FLQNNSLLSIIRAHEAQDAGYRMYRKNQATGFPSLITIFSAPNYLDVYNNKAAVLKYENN 323
           F  +N L  I RAH+    GY            +++TIFSAPNY     N+AA+++ ++ 
Sbjct: 6   FNHSNGLTLISRAHQLVMEGYNWCHDR------NVVTIFSAPNYCYRCGNQAAIMELDDA 167

Query: 324 V-MNIRQFNCSP 334
           +  +  QF+ +P
Sbjct: 168 LKYSFLQFDPAP 203
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|68448542|ref|NP_001020327.1| coiled-coil domain
containing 93 isoform a [Mus musculus]
         (629 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

26603                                                                 210   4e-62
>26603
          Length = 795

 Score =  210 bits (534), Expect(2) = 4e-62,   Method: Compositional matrix adjust.
 Identities = 117/233 (50%), Positives = 148/233 (63%), Gaps = 1/233 (0%)
 Frame = -1

Query: 310 GTSQLHQRKVISLNKQILQKSKHLEELQANHTSLKAKYSDRKKTLTELKDHGXXXXXXXX 369
           G +Q H+R   SLNK I      L E++  H  L   Y + ++ L E++           
Sbjct: 660 GGAQQHKRMTTSLNKHIKDAKTKLNEIEQKHQELHKSYVETQEKLKEVQQRSAAIDEEME 481

Query: 370 XXXXXXXXXXPSMLQNLRALVAMNESLKSQEQEFKAHCREEMARLQQEIETLKAERAPGE 429
                      S+L +LR+LVA+NE+LK QEQEFKAHC+EEMARL+  IE L+ E     
Sbjct: 480 SLTAMETEENQSILSSLRSLVALNENLKKQEQEFKAHCKEEMARLKGNIEDLQRE----- 316

Query: 430 KIISGGEPQGALTSTMTHNEDL-DRRYNMEKEKLYKIRLLQARRNREIAILHRKIDEVPS 488
                    G L +      DL  R+Y+ +KEKL+KIRLL AR+NREIA L RKIDEVPS
Sbjct: 315 --------TGQLDTEDKERADLIGRQYDADKEKLHKIRLLLARKNREIAGLQRKIDEVPS 160

Query: 489 RAELIQYQKRFIELYRQISAVHKETKQFFTLYNTLDDKKVYLEKEISLLNSIH 541
           RAEL QYQ+RF+ELY Q+S+ H+ETKQFFTLYNTLDD K+YL KE++LLNSIH
Sbjct: 159 RAELSQYQRRFVELYNQVSSTHRETKQFFTLYNTLDDTKLYLNKEVNLLNSIH 1

 Score = 47.0 bits (110), Expect(2) = 4e-62,   Method: Compositional matrix adjust.
 Identities = 24/45 (53%), Positives = 33/45 (73%)
 Frame = -2

Query: 266 EESRLTASSVGQIVGLCSEEIKQIVSEYAGKQSELSAEESPEKLG 310
           +E +LTA+ VG IVG+ S+EI QI SEYA KQ+E+   E  E++G
Sbjct: 791 QEXKLTATGVGSIVGMQSQEIXQIASEYAEKQAEIEQIEKSERVG 657
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31560433|ref|NP_059500.2| sorting nexin 3 [Mus
musculus]
         (162 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

01954                                                                 232   5e-62
12345                                                                  43   5e-05
01768                                                                  28   1.2  
09966                                                                  27   2.7  
01196                                                                  27   3.6  
07014                                                                  26   6.0  
09437                                                                  26   6.8  
02041                                                                  26   9.3  
>01954
          Length = 1966

 Score =  232 bits (591), Expect = 5e-62,   Method: Compositional matrix adjust.
 Identities = 115/160 (71%), Positives = 139/160 (86%)
 Frame = -3

Query: 1    MAETVADTRRLITKPQNLNDAYGPPSNFLEIDVSNPQTVGVGRGRFTTYEIRVKTNLPIF 60
            MA T   T R+ +K Q L DAY PP+NFLEID+ +PQT GV + R+T YE+R+K+NLP+F
Sbjct: 1940 MANTA--TARINSKKQTLEDAYSPPANFLEIDIVDPQTHGVAKARYTDYEVRMKSNLPVF 1767

Query: 61   KLKESTVRRRYSDFEWLRSELERESKVVVPPLPGKAFLRQLPFRGDDGIFDDNFIEERKQ 120
            KL++S+VRRRYSDFEWLRSELER+SK+VVPPLPGKA  RQLPFRGDDGIF++ FIEER++
Sbjct: 1766 KLRDSSVRRRYSDFEWLRSELERDSKIVVPPLPGKALKRQLPFRGDDGIFEEEFIEERRK 1587

Query: 121  GLEQFINKVAGHPLAQNERCLHMFLQDEIIDKSYTPSKIR 160
            GLEQFINKVAGHPLAQNE+CLHMFLQ+ +IDK+Y P KIR
Sbjct: 1586 GLEQFINKVAGHPLAQNEKCLHMFLQEPVIDKNYVPGKIR 1467
>12345
          Length = 933

 Score = 43.1 bits (100), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 29/83 (34%), Positives = 43/83 (51%), Gaps = 1/83 (1%)
 Frame = +3

Query: 64  ESTVRRRYSDFEWLRSE-LERESKVVVPPLPGKAFLRQLPFRGDDGIFDDNFIEERKQGL 122
           ++TV RRY+DF  L    + R    ++P LP K  L            +  FIE+RK+ L
Sbjct: 285 KTTVLRRYNDFVALYEMVMMRFPYRILPKLPPKKMLGA----------NREFIEQRKKSL 434

Query: 123 EQFINKVAGHPLAQNERCLHMFL 145
           ++FIN +A HP    ++ L  FL
Sbjct: 435 KRFINIIARHPQINEDKLLKFFL 503
>01768
          Length = 1424

 Score = 28.5 bits (62), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 14/32 (43%), Positives = 18/32 (56%)
 Frame = +3

Query: 92  LPGKAFLRQLPFRGDDGIFDDNFIEERKQGLE 123
           + GK    ++    DDGI DDN IE   QG+E
Sbjct: 42  MAGKGTKDEMEL--DDGILDDNDIESDDQGME 131
>09966
          Length = 1502

 Score = 27.3 bits (59), Expect = 2.7,   Method: Compositional matrix adjust.
 Identities = 15/51 (29%), Positives = 24/51 (47%)
 Frame = -2

Query: 89  VPPLPGKAFLRQLPFRGDDGIFDDNFIEERKQGLEQFINKVAGHPLAQNER 139
           + PL G   L Q   +   GI  D     R +  +Q   ++ G+PLAQ+ +
Sbjct: 787 LQPLKGLRXLSQNGLKXRKGIHTDMHFHSRVKK*QQVSYRILGYPLAQSNK 635
>01196
          Length = 1546

 Score = 26.9 bits (58), Expect = 3.6,   Method: Compositional matrix adjust.
 Identities = 9/32 (28%), Positives = 20/32 (62%)
 Frame = -3

Query: 127 NKVAGHPLAQNERCLHMFLQDEIIDKSYTPSK 158
           + + GH ++ N+RCL ++       ++++PSK
Sbjct: 803 SSIXGHKVSFNKRCLTIYTDQAGXSQNFSPSK 708
>07014
          Length = 1664

 Score = 26.2 bits (56), Expect = 6.0,   Method: Compositional matrix adjust.
 Identities = 9/32 (28%), Positives = 20/32 (62%)
 Frame = -1

Query: 127 NKVAGHPLAQNERCLHMFLQDEIIDKSYTPSK 158
           + + GH ++ N+RCL ++       ++++PSK
Sbjct: 545 SSIXGHKVSFNKRCLTIYTDQAGQSQNFSPSK 450
>09437
          Length = 519

 Score = 26.2 bits (56), Expect = 6.8,   Method: Compositional matrix adjust.
 Identities = 11/19 (57%), Positives = 12/19 (63%)
 Frame = -2

Query: 143 MFLQDEIIDKSYTPSKIRH 161
           MF Q EII K   PSK+ H
Sbjct: 125 MFTQHEIISKPIAPSKLNH 69
>02041
          Length = 1210

 Score = 25.8 bits (55), Expect = 9.3,   Method: Compositional matrix adjust.
 Identities = 8/17 (47%), Positives = 14/17 (82%)
 Frame = -2

Query: 140  CLHMFLQDEIIDKSYTP 156
            C+HM L++E+I  ++TP
Sbjct: 1104 CVHMHLRNEVILSTHTP 1054
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6678760|ref|NP_032892.1| lysophospholipase 1 [Mus
musculus]
         (230 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

17646                                                                 233   6e-62
29258                                                                  27   4.6  
05311                                                                  27   8.9  
25611                                                                  27   10.0 
>17646
          Length = 1240

 Score =  233 bits (593), Expect = 6e-62,   Method: Compositional matrix adjust.
 Identities = 114/202 (56%), Positives = 143/202 (70%)
 Frame = -3

Query: 25   IFLHGLGDTGHGWAEAFAGIKSPHIKYICPHAPVMPVTLNMNMAMPSWFDIVGLSPDSQE 84
            IFLHGLGDTGHGWA+    +K  HIK ICPHAP+ PVTLN  M MPSWFDI GL P S+E
Sbjct: 1073 IFLHGLGDTGHGWADGLQMLKFQHIKCICPHAPIQPVTLNAGMKMPSWFDIQGLDPGSEE 894

Query: 85   DESGIKQAAETVKALIDQEVKNGIPSNRIILGGFSQGGALSLYTALTTQQKLAGVTALSC 144
            D+ GIK+A++ ++ LID E K+GIPS RI +GGFSQGGA++LYTAL   + + GV ALS 
Sbjct: 893  DKKGIKEASKILQELIDNEKKSGIPSERIFIGGFSQGGAVALYTALNVNKPVGGVVALST 714

Query: 145  WLPLRASFSQGPINSANRDISVLQCHGDCDPLVPLMFGSLTVERLKALINPANVTFKIYE 204
            WLPL ++      +  N  + VLQCHG  DP+V   +G  T + LK+L NP N  FK Y+
Sbjct: 713  WLPLHSTLLADKASLHNTGVPVLQCHGTHDPMVRFAWGKKTSDFLKSL-NP-NAQFKSYD 540

Query: 205  GMMHSSCQQEMMDVKHFIDKLL 226
            GMMHSSC +EM D+K F++  L
Sbjct: 539  GMMHSSCPEEMQDLKVFLETHL 474
>29258
          Length = 503

 Score = 27.3 bits (59), Expect = 4.6,   Method: Compositional matrix adjust.
 Identities = 15/45 (33%), Positives = 21/45 (46%)
 Frame = -1

Query: 176 LVPLMFGSLTVERLKALINPANVTFKIYEGMMHSSCQQEMMDVKH 220
           L+PL+   L   +L A  +  N+    YE   H   Q+  MDV H
Sbjct: 338 LLPLLSSFLWSVKLAARNDIVNIGQTSYESTTHXKRQKRRMDVSH 204
>05311
          Length = 1084

 Score = 26.6 bits (57), Expect = 8.9,   Method: Compositional matrix adjust.
 Identities = 16/47 (34%), Positives = 21/47 (44%)
 Frame = -2

Query: 127 YTALTTQQKLAGVTALSCWLPLRASFSQGPINSANRDISVLQCHGDC 173
           +T   +Q  L+   +L  W     S  Q P N  N+ ISV  C G C
Sbjct: 699 WTISVSQDVLSNHKSL--WP*SSRSVEQSPFNQGNQWISVWSCQGTC 565
>25611
          Length = 432

 Score = 26.6 bits (57), Expect = 10.0,   Method: Compositional matrix adjust.
 Identities = 9/18 (50%), Positives = 13/18 (72%)
 Frame = +3

Query: 47 PHIKYICPHAPVMPVTLN 64
          PH+ Y+  H  V+PVTL+
Sbjct: 33 PHLAYVSDHGHVLPVTLD 86
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|27151748|ref|NP_694697.2| nodal modulator 1 [Mus
musculus]
         (1214 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

31939                                                                 156   8e-62
36641                                                                  33   0.93 
19462                                                                  32   2.0  
>31939
          Length = 878

 Score =  156 bits (394), Expect(2) = 8e-62,   Method: Compositional matrix adjust.
 Identities = 71/103 (68%), Positives = 86/103 (83%)
 Frame = -2

Query: 30  GCGGFVKSDVEINYSLIEIKLYTKHGTLKYQTGWAPNNGYFMIPLVDKGDFILKIEPPLG 89
           GCGGFVKSDV+IN+SL+E+KLYT HG++KYQT  APN GY++IPL DKGD+ILK+EPPLG
Sbjct: 712 GCGGFVKSDVDINFSLVEVKLYTPHGSIKYQTDCAPNTGYYLIPLYDKGDYILKVEPPLG 533

Query: 90  WSFEPPHGELRGDGVSDICAKGGGINFLFTGFSVNGKVLSKGQ 132
           WSFEP   +L  DG +D C+ G  INF FTGFSV+GKV+S GQ
Sbjct: 532 WSFEPTSIDLHVDGTTDKCSLGEDINFKFTGFSVSGKVVSAGQ 404

 Score =  100 bits (250), Expect(2) = 8e-62,   Method: Compositional matrix adjust.
 Identities = 51/109 (46%), Positives = 68/109 (62%), Gaps = 1/109 (0%)
 Frame = -3

Query: 135 GPAGVQVSLRSTGADSKIQSTVTQPGGKFAFFKVLPGDYEILATHPTWALKEASTTVRVT 194
           GP GV V+L S   +  +Q+  T  GG +    V+PG+Y + A+HP WA  +A T V+V 
Sbjct: 396 GPEGVSVTLTSXANNQVLQTVHTAVGGSYTITGVMPGNYAVKASHPKWAFSKAETQVKVA 217

Query: 195 NSNANAAGPLIVAGYNVSGSVRSDGEPMKGVKFLLFS-SLVNKEDVLGC 242
           + N NA   L VAGY+V G V S+GEPMKGV F+LF+ S   K+ V GC
Sbjct: 216 DDNTNAGNALSVAGYDVKGQVFSEGEPMKGVNFVLFAQSGSKKQSVGGC 70

 Score = 33.9 bits (76), Expect = 0.43,   Method: Compositional matrix adjust.
 Identities = 11/39 (28%), Positives = 21/39 (53%)
 Frame = -3

Query: 536 TFTFDKVLPGRYKISIMHEDWCWRNKSLEVEVLEDDVSA 574
           ++T   V+PG Y +   H  W +     +V+V +D+ +A
Sbjct: 315 SYTITGVMPGNYAVKASHPKWAFSKAETQVKVADDNTNA 199

 Score = 31.6 bits (70), Expect = 1.8,   Method: Compositional matrix adjust.
 Identities = 25/93 (26%), Positives = 43/93 (46%), Gaps = 12/93 (12%)
 Frame = -2

Query: 277 PSGGYTVVPFY-RGERIT-------FDVAPSRLDF----TVEHDSLRIEPVFHVMGFSVT 324
           P+ GY ++P Y +G+ I        +   P+ +D     T +  SL  +  F   GFSV+
Sbjct: 607 PNTGYYLIPLYDKGDYILKVEPPLGWSFEPTSIDLHVDGTTDKCSLGEDINFKFTGFSVS 428

Query: 325 GRVLNGPDGEGVPEAVVTLNNQIKVKTKADGSF 357
           G+V++          V  L+   +  + ADGS+
Sbjct: 427 GKVVSAGQYRRAGGRVCDLDQCRQQSSSADGSY 329
>36641
          Length = 721

 Score = 32.7 bits (73), Expect = 0.93,   Method: Composition-based stats.
 Identities = 22/60 (36%), Positives = 27/60 (45%)
 Frame = +1

Query: 966  PEQGVAVEAVGQKDCSIYGEDTVTDEEGKFRLRGLLPGCMYHVQLKAEGNDHIERALPHH 1025
            P QGV VEA G +D  +  +          R RGL  GC + VQL       +   LPHH
Sbjct: 325  PAQGVDVEAGGDRDARLSEQ----------R*RGLGHGCTWSVQL-------LNXLLPHH 453
>19462
          Length = 644

 Score = 31.6 bits (70), Expect = 2.0,   Method: Composition-based stats.
 Identities = 13/43 (30%), Positives = 26/43 (60%)
 Frame = +3

Query: 1006 YHVQLKAEGNDHIERALPHHRVIEVGNNDVDDVNIIVFRQINQ 1048
            +H++ +  GND + +AL H+R     +  +++V  I FR++ Q
Sbjct: 180  HHIETQGVGNDVL*QALIHYRKANATHTQIENVVYIRFRELRQ 308
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|7949129|ref|NP_058027.1| synapse-associated protein
102 [Mus musculus]
         (849 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

08480                                                                 234   8e-62
29974                                                                 179   4e-45
29705                                                                 106   5e-40
13641                                                                 144   1e-34
27435                                                                  96   9e-20
33804                                                                  77   2e-18
35802                                                                  89   6e-18
11512                                                                  76   5e-14
20073                                                                  68   1e-11
03831                                                                  60   3e-09
29636                                                                  59   1e-08
27345                                                                  52   1e-06
03499                                                                  45   1e-04
39267                                                                  41   0.002
37412                                                                  39   0.010
38751                                                                  38   0.015
26154                                                                  38   0.016
02951                                                                  35   0.11 
01502                                                                  35   0.12 
12324                                                                  34   0.21 
30740                                                                  34   0.21 
37239                                                                  34   0.31 
01494                                                                  30   3.3  
>08480
          Length = 698

 Score =  234 bits (598), Expect = 8e-62,   Method: Compositional matrix adjust.
 Identities = 124/236 (52%), Positives = 161/236 (68%), Gaps = 13/236 (5%)
 Frame = -1

Query: 436 GPADLSGELRRGDRILSVNGVNLRNATHEQAAAALKRAGQSVTIVAQYRPEEYSRFESKI 495
           GPADLSG+LRRGD+ILSVN V++  ATHEQAA ALKRAG +V I+AQY+PE+Y+RFE+KI
Sbjct: 698 GPADLSGDLRRGDKILSVNDVDVERATHEQAAQALKRAGDTVEIIAQYKPEDYNRFEAKI 519

Query: 496 HDLREQXXXXXXXXXXXXLRTSEKRSLYVRALFDYDRTRDSCLPSQGLSFSYGDILHVIN 555
            DLREQ            LRT++KR+++VRALFDY+ ++DS LPS+GL F YGDILHV N
Sbjct: 518 QDLREQMMNNSAGS----LRTTQKRTMFVRALFDYEPSKDSGLPSRGLWFHYGDILHVTN 351

Query: 556 ASDDEWWQARLVTPHGESEQIGVIPSKKRVEKKERARLKTVKFHARTGMIE--------- 606
           ASDDEWWQA+ + P G+ E +G+IPSK+RVE+KERARL+ VKF   +   +         
Sbjct: 350 ASDDEWWQAKRILPDGKEEGMGIIPSKRRVERKERARLRNVKFGKNSTSTDKPVKDKGKK 171

Query: 607 -SNRDFP-GLSDDYYGAKNLKG--VTXXXXXXXXXXKGQEDAILSYEPVTRQEIHY 658
            S R FP     D  G++++ G  V              E+ +LSYE VT+QE+ Y
Sbjct: 170 KSGRMFPFKKGKDQSGSEDVSGDEVEEGNLPSDSDSNRGEEPVLSYETVTQQELKY 3

 Score = 38.5 bits (88), Expect = 0.010,   Method: Compositional matrix adjust.
 Identities = 31/114 (27%), Positives = 52/114 (45%), Gaps = 2/114 (1%)
 Frame = -1

Query: 282 GAAQKDGRLQIGDRLLAVNNTNLQDVRHEEAVASLKNTSDMVYLKVAKPGSIHLNDMYAP 341
           G A   G L+ GD++L+VN+ +++   HE+A  +LK   D V + +A+         Y P
Sbjct: 698 GPADLSGDLRRGDKILSVNDVDVERATHEQAAQALKRAGDTVEI-IAQ---------YKP 549

Query: 342 PDYASTFTALAD-NHISHNSSLGYLGAVESKVTY-PAPPQVPPTRYSPIPRHML 393
            DY      + D      N+S G L   + +  +  A     P++ S +P   L
Sbjct: 548 EDYNRFEAKIQDLREQMMNNSAGSLRTTQKRTMFVRALFDYEPSKDSGLPSRGL 387

 Score = 37.4 bits (85), Expect = 0.026,   Method: Compositional matrix adjust.
 Identities = 18/39 (46%), Positives = 23/39 (58%)
 Frame = -1

Query: 187 GAAAMDGRLGVNDCVLRVNEVDVSEVVHSRAVEALKEAG 225
           G A + G L   D +L VN+VDV    H +A +ALK AG
Sbjct: 698 GPADLSGDLRRGDKILSVNDVDVERATHEQAAQALKRAG 582
>29974
          Length = 344

 Score =  179 bits (454), Expect = 4e-45,   Method: Compositional matrix adjust.
 Identities = 84/108 (77%), Positives = 94/108 (87%)
 Frame = +1

Query: 673 NDDLISEFPHKFGSCVPHTTRPRRDNEVDGQDYHFVVSREQMEKDIQDNKFIEAGQFNDN 732
           NDDLISEFP KFGSC+PHTTR RR NE  GQDYHFV SREQME+DIQ++ FIEAG +NDN
Sbjct: 1   NDDLISEFPDKFGSCIPHTTRERRTNEEPGQDYHFVSSREQMERDIQNHLFIEAGVYNDN 180

Query: 733 LYGTSIQSVRAVAERGKHCILDVSGNAIKRLQQAQLYPIAIFIKPKSI 780
           LYGTS+ SV+ VAE+G+HCILDVSGNAIKRLQ A LYPIAIFIKP  +
Sbjct: 181 LYGTSVASVKEVAEQGRHCILDVSGNAIKRLQVAGLYPIAIFIKPSRL 324
>29705
          Length = 674

 Score =  106 bits (264), Expect(3) = 5e-40,   Method: Compositional matrix adjust.
 Identities = 51/82 (62%), Positives = 64/82 (78%)
 Frame = -1

Query: 252 KGLGFSIAGGIGNQHIPGDNSIYITKIIEGGAAQKDGRLQIGDRLLAVNNTNLQDVRHEE 311
           +G G     G GNQHIPGDN I+ITK+IEGG+A++DGR+ + DRLLAVN  NL+DV HEE
Sbjct: 422 QGSGIQHCRGKGNQHIPGDNGIFITKVIEGGSAEQDGRIAVMDRLLAVNEHNLEDVTHEE 243

Query: 312 AVASLKNTSDMVYLKVAKPGSI 333
           AVA+LK+T D+V L +AKP  I
Sbjct: 242 AVAALKSTGDVVRLTIAKPTYI 177

 Score = 65.1 bits (157), Expect(3) = 5e-40,   Method: Compositional matrix adjust.
 Identities = 35/76 (46%), Positives = 48/76 (63%), Gaps = 1/76 (1%)
 Frame = -2

Query: 186 GGAAAMDGRLGVNDCVLRVNEVDVSEVVHSRAVEALKEAGXXXXXXXXXXXXXXETIMEV 245
           GGAAA DGRL +ND +++V   DVS   H+ AV+ALK +G              E ++++
Sbjct: 622 GGAAAEDGRLRLNDIIVKVGTEDVSNTTHTAAVDALKRSGNRVYLQVKRLKIPTEKVIDI 443

Query: 246 NLLKG-PKGLGFSIAG 260
           +L+KG  KGLGFSIAG
Sbjct: 442 DLVKGVNKGLGFSIAG 395

 Score = 32.7 bits (73), Expect(3) = 5e-40,   Method: Compositional matrix adjust.
 Identities = 13/22 (59%), Positives = 16/22 (72%)
 Frame = -1

Query: 169 NPHVPDDPGIFITKIIPGGAAA 190
           NPH+ DDP I+ITK+IP G   
Sbjct: 674 NPHIGDDPSIYITKLIPRGCCC 609

 Score = 65.9 bits (159), Expect = 6e-11,   Method: Compositional matrix adjust.
 Identities = 34/68 (50%), Positives = 42/68 (61%)
 Frame = -1

Query: 158 GLGFSIAGGIDNPHVPDDPGIFITKIIPGGAAAMDGRLGVNDCVLRVNEVDVSEVVHSRA 217
           G G     G  N H+P D GIFITK+I GG+A  DGR+ V D +L VNE ++ +V H  A
Sbjct: 419 GSGIQHCRGKGNQHIPGDNGIFITKVIEGGSAEQDGRIAVMDRLLAVNEHNLEDVTHEEA 240

Query: 218 VEALKEAG 225
           V ALK  G
Sbjct: 239 VAALKSTG 216

 Score = 50.8 bits (120), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 24/55 (43%), Positives = 35/55 (63%)
 Frame = -1

Query: 426 GIFVSFILAGGPADLSGELRRGDRILSVNGVNLRNATHEQAAAALKRAGQSVTIV 480
           GIF++ ++ GG A+  G +   DR+L+VN  NL + THE+A AALK  G  V + 
Sbjct: 362 GIFITKVIEGGSAEQDGRIAVMDRLLAVNEHNLEDVTHEEAVAALKSTGDVVRLT 198

 Score = 42.4 bits (98), Expect(2) = 2e-05,   Method: Composition-based stats.
 Identities = 19/49 (38%), Positives = 32/49 (65%)
 Frame = -2

Query: 281 GGAAQKDGRLQIGDRLLAVNNTNLQDVRHEEAVASLKNTSDMVYLKVAK 329
           GGAA +DGRL++ D ++ V   ++ +  H  AV +LK + + VYL+V +
Sbjct: 622 GGAAAEDGRLRLNDIIVKVGTEDVSNTTHTAAVDALKRSGNRVYLQVKR 476

 Score = 25.0 bits (53), Expect(2) = 2e-05,   Method: Compositional matrix adjust.
 Identities = 12/23 (52%), Positives = 14/23 (60%)
 Frame = -1

Query: 264 NQHIPGDNSIYITKIIEGGAAQK 286
           N HI  D SIYITK+I  G   +
Sbjct: 674 NPHIGDDPSIYITKLIPRGCCCR 606

 Score = 35.0 bits (79), Expect = 0.12,   Method: Composition-based stats.
 Identities = 19/43 (44%), Positives = 23/43 (53%)
 Frame = -2

Query: 435 GGPADLSGELRRGDRILSVNGVNLRNATHEQAAAALKRAGQSV 477
           GG A   G LR  D I+ V   ++ N TH  A  ALKR+G  V
Sbjct: 622 GGAAAEDGRLRLNDIIVKVGTEDVSNTTHTAAVDALKRSGNRV 494
>13641
          Length = 2081

 Score =  144 bits (364), Expect = 1e-34,   Method: Compositional matrix adjust.
 Identities = 104/331 (31%), Positives = 172/331 (51%), Gaps = 25/331 (7%)
 Frame = +2

Query: 517 SEKRSLYVRALFDYDRTRDSCLPSQ--GLSFSYGDILHVINASDDEWWQARLVTPHGESE 574
           S+KR + V+A+F ++   D  +P +  GLSF  GDILH++N  D  WWQA     HG+++
Sbjct: 137 SKKREMVVKAMFSFNSKLDDNIPCKEAGLSFQQGDILHIVNQEDAIWWQA---YKHGDAK 307

Query: 575 Q-IGVIPSKKRVEKKE---RARLKTVKFHARTGMIESNRDFPGLSDDYYGAKNLKGVTXX 630
           +  G+IPS+   E++E   +++ K  +  AR+  I   R  P +       + L+     
Sbjct: 308 KRAGLIPSRHYHERQEVLRKSKSKEGRHMARS--ISPCRYSPKVPKQ----RRLRKTMYH 469

Query: 631 XXXXXXXXKGQEDAILSYEPV---TRQEIHYARPVIILGPM---KDRVNDDLISEFPHKF 684
                       D I +Y+ V   T +  H+ RP++++G     ++ +   L +  P  F
Sbjct: 470 IVQNGALTDFDTDEIPAYDEVEHFTPKPRHF-RPIVLIGAPGIGRNELKRRLKASNPMHF 646

Query: 685 GSCVPHTTRPRRDNEVDGQDYHFVVSREQMEKDIQDNKFIEAGQFNDNLYGTSIQSVRAV 744
              VP+TTR ++  E DG++YHFV SRE ME+ I   KF+E G+ + +LYGTS++S++ V
Sbjct: 647 LEVVPYTTRTKKPFEEDGKEYHFV-SREDMEESIIAQKFVEYGEHHGHLYGTSVESIKQV 823

Query: 745 AERGKHCILDVSGNAIKRLQQAQLYPIAIFIKPKSIEALMEMN-------------RRQT 791
              GK C+L     A+K L+  +L P  IFIK  ++E L E               R  +
Sbjct: 824 IAAGKVCLLTPHTQALKFLRTYELKPYVIFIKSPTLEKLKESRMPARARATEADSIRPFS 1003

Query: 792 YEQANKIFDKAMKLEQEFGEYFTAIVQGDSL 822
            E+  ++ + + +LE+ +G  F   +  DSL
Sbjct: 1004IEELEEMAETSRRLEERYGHVFDITIVNDSL 1096
>27435
          Length = 456

 Score = 95.5 bits (236), Expect = 9e-20,   Method: Compositional matrix adjust.
 Identities = 49/151 (32%), Positives = 87/151 (57%), Gaps = 5/151 (3%)
 Frame = +1

Query: 699 EVDGQDYHFVVSREQMEKDIQDNKFIEAGQFNDNLYGTSIQSVRAVAERGKHCILDVSGN 758
           E +G+DYHF+ +R   E D+   KF+E G+F  NLYGT++++VR V ++G+ CIL++   
Sbjct: 1   EHNGKDYHFI-TRAVFEADMLSGKFVEYGEFQGNLYGTTVEAVRQVIQQGRICILNLGPE 177

Query: 759 AIKRLQQAQLYPIAIFIKPKSIEALMEMNR-----RQTYEQANKIFDKAMKLEQEFGEYF 813
           ++K L++ +L P  IFI P  +E L ++       R T +Q  ++ ++  ++E+ +  YF
Sbjct: 178 SLKNLRETELKPYIIFISPPXMEKLRQLQMALGKPRPTDDQVKEVIERGREMEEMYSHYF 357

Query: 814 TAIVQGDSLEEIYNKIKQIIEDQSGHYIWVP 844
             I+    L   ++++ Q I        WVP
Sbjct: 358 DYILVNMELNRAFDELLQEINRIETEPQWVP 450
>33804
          Length = 621

 Score = 77.4 bits (189), Expect(2) = 2e-18,   Method: Composition-based stats.
 Identities = 34/53 (64%), Positives = 44/53 (83%)
 Frame = -1

Query: 797 KIFDKAMKLEQEFGEYFTAIVQGDSLEEIYNKIKQIIEDQSGHYIWVPSPEKL 849
           K F++A+K+EQEFGEYFT +VQGD++EEIY+K+K +I  QSG  IWVPS E L
Sbjct: 561 KHFERAIKMEQEFGEYFTGVVQGDTIEEIYSKVKSMIWSQSGPNIWVPSKESL 403

 Score = 33.9 bits (76), Expect(2) = 2e-18,   Method: Composition-based stats.
 Identities = 14/22 (63%), Positives = 18/22 (81%)
 Frame = -3

Query: 778 KSIEALMEMNRRQTYEQANKIF 799
           KS++++MEMNRR T EQA K F
Sbjct: 619 KSVDSVMEMNRRMTEEQAKKTF 554
>35802
          Length = 571

 Score = 89.4 bits (220), Expect = 6e-18,   Method: Compositional matrix adjust.
 Identities = 54/156 (34%), Positives = 90/156 (57%), Gaps = 10/156 (6%)
 Frame = +1

Query: 699 EVDGQDYHFVVSREQMEKDIQDNKFIEAGQFNDNLYGTSIQSVRAVAERGKHCILDVSGN 758
           E+ G+DYHF  SR   E D+   KF+E G+F  NLYGTS+++VR V  +G+ C+L++   
Sbjct: 1   EMTGRDYHFT-SRSMFEADMLSGKFLEYGEFQSNLYGTSVEAVRQVILQGRVCLLNLEPE 177

Query: 759 AIKRLQQAQLYPIAIFIKPKSIEALMEMN-----RRQTYEQANKIFDKAMKLEQEFGEYF 813
           ++K L++  L P   F+ P ++E L +++      R T +Q   + DK  ++E  +G +F
Sbjct: 178 SLKILRETDLKPYTXFVCPPNMEKLRQLHIAMGKIRPTDDQLKTVMDKGREMEDMYGHFF 357

Query: 814 T-AIVQGD---SLEEIYNKIKQI-IEDQSGHYIWVP 844
              +V  D   S++E+  +I +I +E Q     WVP
Sbjct: 358 DYKLVNMDVDRSVQELMAEINRIEVEPQ-----WVP 450
>11512
          Length = 1006

 Score = 76.3 bits (186), Expect = 5e-14,   Method: Compositional matrix adjust.
 Identities = 43/154 (27%), Positives = 76/154 (49%), Gaps = 14/154 (9%)
 Frame = -3

Query: 706  HFVVSREQMEKDIQDNKFIEAGQFNDNLYGTSIQSVRAVAERGKHCILDVSGNAIKRLQQ 765
            +  V+RE+M+ DI+  KF+E G++  +LYGTS +SV+++   G  C+L     AIK L+ 
Sbjct: 1004 YIFVAREKMDADIEAGKFVEHGEYKGHLYGTSAESVKSIVNAGCVCVLSPHYQAIKTLRT 825

Query: 766  AQLYPIAIFIKPKSIEAL----MEMNRRQTYEQANK----------IFDKAMKLEQEFGE 811
             QL P  I IKP  ++ L     E   + T+++AN           +     +++  +G 
Sbjct: 824  XQLKPFLIHIKPPELDILKSTRTEARAKSTFDEANARSFTDEEFEDMIKSTXRIDFTYGH 645

Query: 812  YFTAIVQGDSLEEIYNKIKQIIEDQSGHYIWVPS 845
            +F   +    L   +  + Q ++      +W PS
Sbjct: 644  FFDVEIVNGELLAAFEXLVQHVQRLENEPLWAPS 543
>20073
          Length = 582

 Score = 68.2 bits (165), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 37/83 (44%), Positives = 53/83 (63%), Gaps = 1/83 (1%)
 Frame = +3

Query: 413 GLGFNIVGG-EDGEGIFVSFILAGGPADLSGELRRGDRILSVNGVNLRNATHEQAAAALK 471
           GLGFN++GG E    I++S I+ GG AD    L+RGD++LSVNGV++    HE+A   LK
Sbjct: 3   GLGFNVMGGKEQSSPIYISRIIPGGVADRLNCLKRGDQLLSVNGVSVEGEYHEKAVELLK 182

Query: 472 RAGQSVTIVAQYRPEEYSRFESK 494
            A  SV +V +Y P+     E++
Sbjct: 183 LAQGSVRLVVRYTPQILEEMEAR 251

 Score = 47.8 bits (112), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 32/75 (42%), Positives = 44/75 (58%)
 Frame = +3

Query: 253 GLGFSIAGGIGNQHIPGDNSIYITKIIEGGAAQKDGRLQIGDRLLAVNNTNLQDVRHEEA 312
           GLGF++ GG   Q  P    IYI++II GG A +   L+ GD+LL+VN  +++   HE+A
Sbjct: 3   GLGFNVMGG-KEQSSP----IYISRIIPGGVADRLNCLKRGDQLLSVNGVSVEGEYHEKA 167

Query: 313 VASLKNTSDMVYLKV 327
           V  LK     V L V
Sbjct: 168 VELLKLAQGSVRLVV 212

 Score = 42.4 bits (98), Expect = 8e-04,   Method: Compositional matrix adjust.
 Identities = 29/67 (43%), Positives = 37/67 (55%)
 Frame = +3

Query: 158 GLGFSIAGGIDNPHVPDDPGIFITKIIPGGAAAMDGRLGVNDCVLRVNEVDVSEVVHSRA 217
           GLGF++ GG +       P I+I++IIPGG A     L   D +L VN V V    H +A
Sbjct: 3   GLGFNVMGGKEQ----SSP-IYISRIIPGGVADRLNCLKRGDQLLSVNGVSVEGEYHEKA 167

Query: 218 VEALKEA 224
           VE LK A
Sbjct: 168 VELLKLA 188
>03831
          Length = 1143

 Score = 60.5 bits (145), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 57/216 (26%), Positives = 92/216 (42%), Gaps = 9/216 (4%)
 Frame = +3

Query: 274 YITKIIEGGAAQKDGRLQIGDRLLAVNNTNLQDVRHEEAVASLKNTSDMVYLKVA-KPGS 332
           +I K+ EG  A+  G L+ GDR++ VN TN+ +  H++ V  +K   D   L V  +   
Sbjct: 213 FIGKVDEGSPAEAAG-LKAGDRIVEVNGTNIGNENHQQVVGRIKAGGDETRLLVVDQETD 389

Query: 333 IHLND--MYAPPDYAST--FTALADNHISHNSSLGYLGAV--ESKVTYPAPPQVP--PTR 384
            H  +       D   T   TA  +   +  +    + AV   +  T P P  +P   + 
Sbjct: 390 QHYKEEKRVVRGDLPETRFMTAAREQKDNXENQEAEIAAVVEATNGTEPEPQSLPDESSL 569

Query: 385 YSPIPRHMLAEEDFTREPRKIILHKGSTGLGFNIVGGEDGEGIFVSFILAGGPADLSGEL 444
           Y+P   H+    DF              G GFN+   +D  G ++  +    PA+  G L
Sbjct: 570 YAPRLCHLCKWADF-------------DGYGFNLHAEKDKPGQYIGSVDPNSPAETGG-L 707

Query: 445 RRGDRILSVNGVNLRNATHEQAAAALKRAGQSVTIV 480
           + GDRI+ VNG N+    H      +K  G   +++
Sbjct: 708 KEGDRIIEVNGENIETTNHTAVIQNIKSRGDKTSML 815

 Score = 48.9 bits (115), Expect = 9e-06,   Method: Compositional matrix adjust.
 Identities = 26/85 (30%), Positives = 46/85 (54%), Gaps = 1/85 (1%)
 Frame = +3

Query: 412 TGLGFNIVGGEDGEGIFVSFILAGGPADLSGELRRGDRILSVNGVNLRNATHEQAAAALK 471
            G GFN+   +   G F+  +  G PA+ +G L+ GDRI+ VNG N+ N  H+Q    +K
Sbjct: 165 NGYGFNLHAEKGKAGQFIGKVDEGSPAEAAG-LKAGDRIVEVNGTNIGNENHQQVVGRIK 341

Query: 472 RAG-QSVTIVAQYRPEEYSRFESKI 495
             G ++  +V     +++ + E ++
Sbjct: 342 AGGDETRLLVVDQETDQHYKEEKRV 416
>29636
          Length = 354

 Score = 58.5 bits (140), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 34/77 (44%), Positives = 44/77 (57%), Gaps = 6/77 (7%)
 Frame = +1

Query: 522 LYVRALFDYDRTRDSCLPSQ--GLSFSYGDILHVINASDDEWWQARLVTPHGESEQ---- 575
           +++RALF+YD   D  +P +  G+SF  GDILH I  SD  WWQA     H E E     
Sbjct: 70  MHLRALFNYDPEDDPYIPCRELGISFLKGDILHAIQLSDSNWWQA-----HREGEDAHML 234

Query: 576 IGVIPSKKRVEKKERAR 592
            G+IPSK   E++E  R
Sbjct: 235 AGLIPSKAFQEQRESVR 285
>27345
          Length = 496

 Score = 51.6 bits (122), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 24/62 (38%), Positives = 38/62 (61%)
 Frame = +3

Query: 268 PGDNSIYITKIIEGGAAQKDGRLQIGDRLLAVNNTNLQDVRHEEAVASLKNTSDMVYLKV 327
           PG   I+I  + +GGAAQKDGR+Q+ D+++ V+  +L  V    A + L+NTS  V   +
Sbjct: 12  PGKLGIFIKTLTDGGAAQKDGRIQVNDQIIEVDGKSLVGVTQAYAASVLRNTSGQVTFHI 191

Query: 328 AK 329
            +
Sbjct: 192 GR 197

 Score = 38.1 bits (87), Expect = 0.015,   Method: Compositional matrix adjust.
 Identities = 19/50 (38%), Positives = 27/50 (54%)
 Frame = +3

Query: 173 PDDPGIFITKIIPGGAAAMDGRLGVNDCVLRVNEVDVSEVVHSRAVEALK 222
           P   GIFI  +  GGAA  DGR+ VND ++ V+   +  V  + A   L+
Sbjct: 12  PGKLGIFIKTLTDGGAAQKDGRIQVNDQIIEVDGKSLVGVTQAYAASVLR 161
>03499
          Length = 1247

 Score = 45.4 bits (106), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 30/93 (32%), Positives = 48/93 (51%), Gaps = 11/93 (11%)
 Frame = -3

Query: 398  FTREP-------RKIILHKGSTGLGFNIVGGE--DGEGIFVSFILAGGPADLSGELRRGD 448
            FT++P        K  L K   G GF IVG +  D E + +  ++  GPA L+G+L+ GD
Sbjct: 1014 FTKQPGELQGEFVKTSLVKSVRGFGFTIVGSDHPDTEFLQIKNVVPNGPAYLNGKLKTGD 835

Query: 449  RILSVNGVNLRNATHEQAAAALK--RAGQSVTI 479
             I+ VN   +   TH+   +  +    G++VT+
Sbjct: 834  VIVFVNTTCVLGYTHQDVVSLFQTISPGETVTL 736
>39267
          Length = 456

 Score = 40.8 bits (94), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 27/61 (44%), Positives = 34/61 (55%)
 Frame = +1

Query: 413 GLGFNIVGGEDGEGIFVSFILAGGPADLSGELRRGDRILSVNGVNLRNATHEQAAAALKR 472
           GLGFNI G    +GI+VS +   GPA  SG++  GDRI SV  +   N  +E A   L  
Sbjct: 115 GLGFNISGNMR-DGIYVSQLHNRGPASESGKIHVGDRIQSVT-IAYDNIVYEDALTILSY 288

Query: 473 A 473
           A
Sbjct: 289 A 291

 Score = 34.3 bits (77), Expect = 0.20,   Method: Compositional matrix adjust.
 Identities = 19/68 (27%), Positives = 38/68 (55%)
 Frame = +1

Query: 253 GLGFSIAGGIGNQHIPGDNSIYITKIIEGGAAQKDGRLQIGDRLLAVNNTNLQDVRHEEA 312
           GLGF+I+G +        + IY++++   G A + G++ +GDR+ +V      ++ +E+A
Sbjct: 115 GLGFNISGNM-------RDGIYVSQLHNRGPASESGKIHVGDRIQSV-TIAYDNIVYEDA 270

Query: 313 VASLKNTS 320
           +  L   S
Sbjct: 271 LTILSYAS 294
>37412
          Length = 757

 Score = 38.9 bits (89), Expect = 0.010,   Method: Composition-based stats.
 Identities = 17/39 (43%), Positives = 25/39 (64%)
 Frame = -3

Query: 748 GKHCILDVSGNAIKRLQQAQLYPIAIFIKPKSIEALMEM 786
           GK C+LDV+  ++K L+ A+  P  +FI   S+EAL  M
Sbjct: 629 GKMCVLDVNPTSLKVLKTAEFLPYIVFIAAPSVEALKVM 513
>38751
          Length = 329

 Score = 38.1 bits (87), Expect = 0.015,   Method: Composition-based stats.
 Identities = 20/51 (39%), Positives = 31/51 (60%)
 Frame = +3

Query: 273 IYITKIIEGGAAQKDGRLQIGDRLLAVNNTNLQDVRHEEAVASLKNTSDMV 323
           I +  I EG  A++ G L IGDR+L VN T+   + H EAV  ++N  +++
Sbjct: 39  IVVYVIEEGCQAEQQG-LNIGDRILDVNGTDFTHLTHAEAVTIMRNAWNVI 188

 Score = 36.6 bits (83), Expect = 0.039,   Method: Composition-based stats.
 Identities = 27/70 (38%), Positives = 35/70 (50%)
 Frame = +3

Query: 420 GGEDGEGIFVSFILAGGPADLSGELRRGDRILSVNGVNLRNATHEQAAAALKRAGQSVTI 479
           G E G  I V  I  G  A+  G L  GDRIL VNG +  + TH +A   ++ A  +V +
Sbjct: 18  GKEYGTPIVVYVIEEGCQAEQQG-LNIGDRILDVNGTDFTHLTHAEAVTIMRNA-WNVIM 191

Query: 480 VAQYRPEEYS 489
             Q  PE  S
Sbjct: 192 TVQPCPESDS 221
>26154
          Length = 446

 Score = 38.1 bits (87), Expect = 0.016,   Method: Composition-based stats.
 Identities = 23/61 (37%), Positives = 34/61 (55%)
 Frame = -3

Query: 245 VNLLKGPKGLGFSIAGGIGNQHIPGDNSIYITKIIEGGAAQKDGRLQIGDRLLAVNNTNL 304
           V L +    LG +I+G       P DN I I+++  GG AQK G + +GDRLL +N +  
Sbjct: 222 VQLYRHGGPLGITISG----TEDPLDN-IVISELTAGGLAQKTGAMHVGDRLLGINESTT 58

Query: 305 Q 305
           +
Sbjct: 57  K 55

 Score = 34.3 bits (77), Expect = 0.21,   Method: Composition-based stats.
 Identities = 21/69 (30%), Positives = 35/69 (50%), Gaps = 1/69 (1%)
 Frame = -3

Query: 407 LHKGSTGLGFNIVGGEDG-EGIFVSFILAGGPADLSGELRRGDRILSVNGVNLRNATHEQ 465
           L++    LG  I G ED  + I +S + AGG A  +G +  GDR+L +N    + +   +
Sbjct: 216 LYRHGGPLGITISGTEDPLDNIVISELTAGGLAQKTGAMHVGDRLLGINESTTKTSPCRK 37

Query: 466 AAAALKRAG 474
            +A  +  G
Sbjct: 36  LSACCRVPG 10

 Score = 33.5 bits (75), Expect = 0.34,   Method: Composition-based stats.
 Identities = 16/48 (33%), Positives = 29/48 (60%)
 Frame = -3

Query: 282 GAAQKDGRLQIGDRLLAVNNTNLQDVRHEEAVASLKNTSDMVYLKVAK 329
           G+A + G +Q GD+L+A+N+  L     ++A   L+   ++V LKV +
Sbjct: 408 GSAHRCGSIQAGDKLMAINDVRLDTCTVDDATHLLELPDELVKLKVQR 265
>02951
          Length = 1076

 Score = 35.4 bits (80), Expect = 0.11,   Method: Composition-based stats.
 Identities = 19/52 (36%), Positives = 30/52 (57%)
 Frame = +2

Query: 421 GEDGEGIFVSFILAGGPADLSGELRRGDRILSVNGVNLRNATHEQAAAALKR 472
           G   +GI+V+FI    PA   G L+  D+IL +NG +    TH+QA   +++
Sbjct: 5   GYPDKGIYVTFIYENSPAARCG-LQLHDKILQLNGKDFTVVTHKQAVENIRK 157
>01502
          Length = 1949

 Score = 35.0 bits (79), Expect = 0.12,   Method: Composition-based stats.
 Identities = 18/48 (37%), Positives = 29/48 (60%)
 Frame = +1

Query: 425 EGIFVSFILAGGPADLSGELRRGDRILSVNGVNLRNATHEQAAAALKR 472
           +GI+V+FI    PA   G L+  D+IL +NG +    TH+QA   +++
Sbjct: 31  KGIYVTFIYENSPAARCG-LQLHDKILQLNGKDFTVVTHKQAVENIRK 171
>12324
          Length = 946

 Score = 34.3 bits (77), Expect = 0.21,   Method: Compositional matrix adjust.
 Identities = 14/43 (32%), Positives = 25/43 (58%)
 Frame = +3

Query: 524 VRALFDYDRTRDSCLPSQGLSFSYGDILHVINASDDEWWQARL 566
           V A++DY+  +D  L     +FS   +++VI  +DD WW+  +
Sbjct: 696 VVAIYDYEAEKDDEL-----TFSENSVIYVIRKNDDGWWEGVM 809
>30740
          Length = 488

 Score = 34.3 bits (77), Expect = 0.21,   Method: Compositional matrix adjust.
 Identities = 13/25 (52%), Positives = 18/25 (72%)
 Frame = +2

Query: 541 QGLSFSYGDILHVINASDDEWWQAR 565
           + L FS GDIL +I+  ++EWW AR
Sbjct: 227 EDLPFSKGDILELISKDEEEWWTAR 301
>37239
          Length = 453

 Score = 33.9 bits (76), Expect = 0.31,   Method: Composition-based stats.
 Identities = 16/28 (57%), Positives = 19/28 (67%)
 Frame = -3

Query: 269 GDNSIYITKIIEGGAAQKDGRLQIGDRL 296
           G + IYI  I  GGAA KDG+L +GD L
Sbjct: 85  GRHGIYIRHITIGGAAAKDGQLAVGDEL 2

 Score = 29.6 bits (65), Expect = 5.8,   Method: Composition-based stats.
 Identities = 14/23 (60%), Positives = 16/23 (69%)
 Frame = -3

Query: 177 GIFITKIIPGGAAAMDGRLGVND 199
           GI+I  I  GGAAA DG+L V D
Sbjct: 76  GIYIRHITIGGAAAKDGQLAVGD 8
>01494
          Length = 2122

 Score = 30.4 bits (67), Expect = 3.3,   Method: Compositional matrix adjust.
 Identities = 16/42 (38%), Positives = 22/42 (52%)
 Frame = +3

Query: 522 LYVRALFDYDRTRDSCLPSQGLSFSYGDILHVINASDDEWWQ 563
           L V+AL DY+  RD       LSF  G I+  ++  D  WW+
Sbjct: 306 LRVKALHDYNANRDD-----ELSFCKGAIITNVSRQDGGWWR 416
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|110625624|ref|NP_038714.2| t-complex protein 1 [Mus
musculus]
         (556 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

01159                                                                 233   1e-61
05356                                                                 136   3e-60
09900                                                                 152   3e-37
06409                                                                 134   8e-32
29864                                                                 124   8e-29
12796                                                                 117   1e-26
29631                                                                 115   3e-26
33770                                                                  92   6e-19
30661                                                                  59   5e-09
25854                                                                  55   6e-08
17249                                                                  53   4e-07
31574                                                                  30   3.6  
>01159
          Length = 2613

 Score =  233 bits (595), Expect = 1e-61,   Method: Compositional matrix adjust.
 Identities = 172/529 (32%), Positives = 287/529 (54%), Gaps = 9/529 (1%)
 Frame = +3

Query: 11  RSTGEAVRSQNVMAAASIANIVKSSFGPVGLDKMLVDDIGDVTITNDGATILKLLEVEHP 70
           R TG      +++AA S+A+I+K+S GP GLDKM+V   GDVT+TNDGATIL +++V+H 
Sbjct: 171 RLTGIEAHKSHILAAKSVASILKTSLGPKGLDKMMVSGDGDVTVTNDGATILDMMDVDHQ 350

Query: 71  AAKVLCELADLQDKEVGDGTTSVVIIAAELLKNADELVKQKIHPTSVISGYRLACKEAVR 130
            AK++ +L+  QD E+GDGTT VV++A  LL+ A++L+ + IHP  +  GY +A K AV 
Sbjct: 351 IAKLMVQLSKSQDDEIGDGTTGVVVLAGALLEQAEKLLDRGIHPIRIADGYEIAAKCAVE 530

Query: 131 Y---INENLIINTDELGRDCLINAAKTSMSSKIIGINGDYFANMVVDAVLAVKYTDARGQ 187
               I++N     D    + LI  A T++ SKI+       A + VDA+++V   D +  
Sbjct: 531 TLDKISDNY--EVDLKNAEPLIKLAMTTLGSKIVNRCHRQMAKIAVDAIMSV--ADLK-- 692

Query: 188 PRYPVNSVNILKAHGR--SQIE-SMLINGYALNCVVGSQGMPKRIVNAKIACLDFSLQKT 244
            R  V+   ++K  G+   ++E +ML+ G  ++  +    MPK + +AKIA L    +  
Sbjct: 693 -RKDVD-FELIKVEGKVGGKLEDTMLVKGVVVDKDMSHPQMPKVVKDAKIAILTCPFEPP 866

Query: 245 KMKLGVQVVITDPEKLDQIRQRESDITKERIQKILATGANVILTTGGIDDMYLKYFVEAG 304
           K K   ++ IT  E   ++R+ E +  +  +Q +   GAN+++   G DD      ++  
Sbjct: 867 KPKTKHKLDITSVEDYKKLREYELNKFESMVQSVKDKGANLVICQWGFDDEANHLLLQRE 1046

Query: 305 AMAVRRVLKRDLKHVAKASGASILSTLANLEGEETFEVTMLGQAEEVVQER---ICDDEL 361
             AVR V   +++ +A A+G  I+     L  E+      LG+A  +V+E       D +
Sbjct: 1047LPAVRWVGGPEIELIAIATGGRIVPRFEELTTEK------LGKA-GIVRELTFGTTKDRM 1205

Query: 362 ILIKNTKARTSASIILRGANDFMCDEMERSLHDALCVVKRVLELKSVVPGGGAVEAALSI 421
           ++I+      + +I +RG N  + +E +RSLHDALCV++ ++    VV GGGA E A S+
Sbjct: 1206LVIEECLNTRAVTIFIRGGNKMIVEEAKRSLHDALCVIRNLVRDNRVVYGGGAPEIAASV 1385

Query: 422 YLENYATSMGSREQLAIAEFARSLLVIPNTLAVNAAQDSTDLVAKLRAFHNEAQVNPERK 481
            +   A  + + EQ A+  F+ +L  +P  LA N+       +A++++   + + NP   
Sbjct: 1386AVAEAADKISTLEQYAVRSFSEALEAVPLALAENSGLAPIQTLAEVKSRQVKEK-NPR-- 1556

Query: 482 NLKWIGLDLVHGKPRDNKQAGVFEPTIVKVKSLKFATEAAITILRIDDL 530
               +G+D +     D K+  V E    K + +  AT+    IL+IDD+
Sbjct: 1557----LGIDCLLKGTNDMKEQNVIETLTAKKQQILLATQLVRMILKIDDI 1691
>05356
          Length = 2339

 Score =  136 bits (342), Expect(2) = 3e-60,   Method: Compositional matrix adjust.
 Identities = 89/272 (32%), Positives = 153/272 (56%), Gaps = 1/272 (0%)
 Frame = +2

Query: 20  QNVMAAASIANIVKSSFGPVGLDKMLVDDIGDVTITNDGATILKLLEVEHPAAKVLCELA 79
           +N+ A   +A   +S++GP G +KM+++ +  + +TND ATIL+ LEV+HPAAK+L   A
Sbjct: 281 RNIEACKELAKTTRSAYGPHGQNKMVINHLEKLFVTNDAATILRELEVQHPAAKMLVLAA 460

Query: 80  DLQDKEVGDGTTSVVIIAAELLKNADELVKQKIHPTSVISGYRLACKEAVRYINENLIIN 139
             Q++E GDGT  V++ A  LL+NA++L++  +  T VI GY LA K+A   + + +I +
Sbjct: 461 HQQEQECGDGTNFVLVFAGALLENAEQLLRMGLSVTEVIEGYELALKKAHEILPKLVIGH 640

Query: 140 TDEL-GRDCLINAAKTSMSSKIIGINGDYFANMVVDAVLAVKYTDARGQPRYPVNSVNIL 198
              L  ++ +  A +TS+ SK  G N D+ A+++ DA ++V       +  + V++V + 
Sbjct: 641 VKNLRNKEEVKTAIRTSVMSKQYG-NEDFLADLITDACVSV----LPAKISFSVDNVRVC 805

Query: 199 KAHGRSQIESMLINGYALNCVVGSQGMPKRIVNAKIACLDFSLQKTKMKLGVQVVITDPE 258
           K  G   ++S  I G      V  +G   ++  AK+A     L   + +    V+I + E
Sbjct: 806 KILGCGLLQSSTIQGMVFKRQV--EGEITKVEKAKVAVFTCPLDSMQTETKGTVLIKNAE 979

Query: 259 KLDQIRQRESDITKERIQKILATGANVILTTG 290
           +L    + E D+ +E+I+ I   G NVI+  G
Sbjct: 980 ELMSFSKGEEDMMEEQIKGIKEAGVNVIVAGG 1075

 Score =  114 bits (285), Expect(2) = 3e-60,   Method: Compositional matrix adjust.
 Identities = 77/250 (30%), Positives = 126/250 (50%), Gaps = 2/250 (0%)
 Frame = +1

Query: 288  TTGGIDDMYLKYFVEAGAMAVRRVLKRDLKHVAKASGASILSTLANLEGEETFEVTMLGQ 347
            + G + D+   Y  +   M +R + K DL+ + K+  A+ L  +     EE       G 
Sbjct: 1066 SWGEVGDLAQHYCNKYKVMVIRLLSKWDLRRLCKSICATALPKVTTPRNEEC------GY 1227

Query: 348  AEEVVQERICDDELILIKNTKARTS-ASIILRGANDFMCDEMERSLHDALCVVKRVLELK 406
             + V  + I +  +++ +  K  +   ++I+RG+ D + D++ER+L D +   K + +  
Sbjct: 1228 CDLVYVDEIGETPVVIFQQNKDESPITTVIIRGSTDNIMDDIERALDDGVNTFKALTKDD 1407

Query: 407  SVVPGGGAVEAALSIYLENYATSMGSREQLAIAEFARSLLVIPNTLAVNAAQDSTDLVAK 466
             +VPG GA E  L+  +  Y  S+   EQ A+ +FA SL VIP  LA N    +TD+++K
Sbjct: 1408 RLVPGAGATEIELAKQITTYGESLPGLEQYAVKKFAESLEVIPRALAENTGMKATDILSK 1587

Query: 467  LRAFHNEAQVNPERKNLKWIGLDL-VHGKPRDNKQAGVFEPTIVKVKSLKFATEAAITIL 525
            L A H E Q N         G+D+   G   D KQA + +  + +   LKFA  AA T+L
Sbjct: 1588 LYAAHQEGQQNA--------GVDIDDSGSVLDAKQANLTDLYLNRYWGLKFAAAAACTVL 1743

Query: 526  RIDDLIKLHP 535
            R+D +I   P
Sbjct: 1744 RVDQIIMAKP 1773
>09900
          Length = 1305

 Score =  152 bits (384), Expect = 3e-37,   Method: Compositional matrix adjust.
 Identities = 95/312 (30%), Positives = 166/312 (53%)
 Frame = +3

Query: 233 KIACLDFSLQKTKMKLGVQVVITDPEKLDQIRQRESDITKERIQKILATGANVILTTGGI 292
           +IA L+  L+    +   +V + + ++   I   E  I  +++ KI  +GA V+L+   I
Sbjct: 60  RIALLNIELELKSERDNAEVRVDNVQEYQSIVDAEWKILYDKLDKIHQSGAKVVLSKLPI 239

Query: 293 DDMYLKYFVEAGAMAVRRVLKRDLKHVAKASGASILSTLANLEGEETFEVTMLGQAEEVV 352
            D+  +YF +       RV + DL+   KA G SI +T+ +L  +      +LG  +   
Sbjct: 240 GDVATQYFADRDMFCAGRVPEEDLRRTMKACGGSIQTTVQSLTPD------VLGTCQLFD 401

Query: 353 QERICDDELILIKNTKARTSASIILRGANDFMCDEMERSLHDALCVVKRVLELKSVVPGG 412
           + +I  +   + K      + +IILRG  +   +E ERSLHDA+ +V+R ++  SVV GG
Sbjct: 402 EIQIGGERFNMFKGCTMARTCTIILRGGAEQFMEETERSLHDAIMIVRRAIKNDSVVAGG 581

Query: 413 GAVEAALSIYLENYATSMGSREQLAIAEFARSLLVIPNTLAVNAAQDSTDLVAKLRAFHN 472
           GA+E  +S +L  ++ ++  +EQL ++ +A++L VIP  L  NA  D+T+++ KLR  H 
Sbjct: 582 GAIEMEVSYHLREHSHTIAGKEQLLMSAYAKALEVIPRQLCDNAGFDATNILNKLRQKHA 761

Query: 473 EAQVNPERKNLKWIGLDLVHGKPRDNKQAGVFEPTIVKVKSLKFATEAAITILRIDDLIK 532
           +           W G++++     DN +  V+EP +VK+ +L  A+EA   IL +D+ IK
Sbjct: 762 QGGT--------WYGVNILREDIADNFEDCVWEPAVVKINALTAASEATALILSVDETIK 917

Query: 533 LHPESKDDKHGS 544
                + D  G+
Sbjct: 918 NPRSGQGDAPGA 953
>06409
          Length = 1533

 Score =  134 bits (337), Expect = 8e-32,   Method: Compositional matrix adjust.
 Identities = 87/316 (27%), Positives = 162/316 (51%), Gaps = 8/316 (2%)
 Frame = -3

Query: 224  GMPKRIVNAKIACLDFSLQKTKMKLGVQVVITDPEKLDQIRQRESDITKERIQKILATGA 283
            G P ++  AKI  + F +   K  +  QV+++D  ++D++ + E +   + ++KI   G 
Sbjct: 1507 GGPSKVEKAKIGFIQFCISPPKTDMENQVIVSDYTQMDRVLREERNYILDIVKKIKKAGC 1328

Query: 284  NVILTTGGI-----DDMYLKYFVEAGAMAVRRVLKRDLKHVAKASGASILSTLANLEGEE 338
            NV+L    I      D+ L +  +   M V+ + + D++ V K  G   +++L +   E 
Sbjct: 1327 NVLLIQKSILRDAVSDLALHFLAKMKIMVVKDIEREDVEFVCKTLGCRPVASLDHFLPEN 1148

Query: 339  TFEVTMLGQAEEVVQERICDDELILIKNT---KARTSASIILRGANDFMCDEMERSLHDA 395
                  LG A+ +  E +      ++K T       + ++++RG+N  + +E +RSLHDA
Sbjct: 1147 ------LGSADLI--EEVQTGSSKIVKATGIANPGQTVTVLIRGSNKLVLEEADRSLHDA 992

Query: 396  LCVVKRVLELKSVVPGGGAVEAALSIYLENYATSMGSREQLAIAEFARSLLVIPNTLAVN 455
            LCV++ +++ K+++ GGGA E  +S+ L  YA ++   EQ     FA +L VIP TLA N
Sbjct: 991  LCVIRCLVKKKALIAGGGAPETEMSMRLAAYANTLAGMEQYCFRAFAEALEVIPFTLAEN 812

Query: 456  AAQDSTDLVAKLRAFHNEAQVNPERKNLKWIGLDLVHGKPRDNKQAGVFEPTIVKVKSLK 515
            A  +    V  LR  H + +        +  G+++  G   +  +  V +P +V   ++ 
Sbjct: 811  AGLNPISTVTXLRTRHAQGE--------RTAGINVRKGAITNILEENVLQPLLVSTSAIT 656

Query: 516  FATEAAITILRIDDLI 531
             A+E   +IL+IDD++
Sbjct: 655  LASETVRSILKIDDIV 608
>29864
          Length = 1026

 Score =  124 bits (312), Expect = 8e-29,   Method: Compositional matrix adjust.
 Identities = 75/257 (29%), Positives = 136/257 (52%)
 Frame = +1

Query: 21  NVMAAASIANIVKSSFGPVGLDKMLVDDIGDVTITNDGATILKLLEVEHPAAKVLCELAD 80
           N+ AA  + ++++S+ GP G  KMLV   GD+ +T DG  +L  ++++HP A ++  +A 
Sbjct: 175 NIAAAKGLQDVLRSNLGPKGTMKMLVSGAGDIKLTKDGNVLLHEMQIQHPTASLIARVAT 354

Query: 81  LQDKEVGDGTTSVVIIAAELLKNADELVKQKIHPTSVISGYRLACKEAVRYINENLIINT 140
            QD   GDGTTS V+I  ELLK AD  + + +HP  +  G+ LA  +A+  + E  +   
Sbjct: 355 AQDDITGDGTTSNVLIIGELLKQADLYIAEGLHPRLITEGFELARNKALEVLEEVKV--K 528

Query: 141 DELGRDCLINAAKTSMSSKIIGINGDYFANMVVDAVLAVKYTDARGQPRYPVNSVNILKA 200
            E+ R+ L+  A+TS+ +K+     D     VVDAVLA++     G     ++ V +++ 
Sbjct: 529 REVDRETLVQVARTSLRTKVHTELADLLTEHVVDAVLAIQXP-GEG---IDLHMVELMEM 696

Query: 201 HGRSQIESMLINGYALNCVVGSQGMPKRIVNAKIACLDFSLQKTKMKLGVQVVITDPEKL 260
             ++ ++S L+ G  ++       M K   +A I   + SL+  K ++         ++ 
Sbjct: 697 QHKTDLDSTLVRGLVMDHGARHPDMKKHTKDAFILTCNVSLEYEKTEVNSGFFYKTAQER 876

Query: 261 DQIRQRESDITKERIQK 277
           +++ + E     ER++K
Sbjct: 877 EKLVEAERTFIDERVRK 927
>12796
          Length = 1316

 Score =  117 bits (294), Expect = 1e-26,   Method: Compositional matrix adjust.
 Identities = 92/346 (26%), Positives = 167/346 (48%), Gaps = 5/346 (1%)
 Frame = -3

Query: 194  SVNILKAHGRSQIESMLINGYALNCVVGSQGMPKRIVNAKIACLDFSLQKTKMKLGVQVV 253
            ++ ++++ G +  ++ L+NG            PKRI  AKI  + F +   K  +   V+
Sbjct: 1296 NIKVIRSLGGTVEDTELVNGLVFTSRSAGTNAPKRIEKAKIGLIQFCISAPKTDMDHNVI 1117

Query: 254  ITDPEKLDQIRQRESDITKERIQKILATGANVILTTGGI-----DDMYLKYFVEAGAMAV 308
            ++D   +D++ + E       +++I   G NV+L    I      D+   +  +   + V
Sbjct: 1116 VSDYAAMDRVLKEERSYILNIVKQIKKAGCNVLLVQKSILRDAVSDLAQHFLDKIKCLVV 937

Query: 309  RRVLKRDLKHVAKASGASILSTLANLEGEETFEVTMLGQAEEVVQERICDDELILIKNTK 368
            + V + D++ V K      +++L +   E      ++   EEV        ++  I+N +
Sbjct: 936  KDVEREDIEFVCKTLHCRPIASLDHFTAENMSSADLV---EEVASGTNKFVKITGIQN-Q 769

Query: 369  ARTSASIILRGANDFMCDEMERSLHDALCVVKRVLELKSVVPGGGAVEAALSIYLENYAT 428
             RT  SII RG+N  + +E  RSLHDALCVV+ ++  ++ + GGGA E  +++ L   A 
Sbjct: 768  GRT-VSIICRGSNKLVLEEAARSLHDALCVVRCLVRNRAQIVGGGAPEIEMALQLAAAAQ 592

Query: 429  SMGSREQLAIAEFARSLLVIPNTLAVNAAQDSTDLVAKLRAFHNEAQVNPERKNLKWIGL 488
            ++   +      FA +L VIP+TLA NA  +    V +LR  H + + N         G+
Sbjct: 591  TVDGVDAYCYRAFADALEVIPSTLAENAGLNPIATVTELRNRHAQGEKNA--------GI 436

Query: 489  DLVHGKPRDNKQAGVFEPTIVKVKSLKFATEAAITILRIDDLIKLH 534
            ++  G   D     V +P +V   ++  ATE   +IL+IDD++  +
Sbjct: 435  NVRKGAITDIFAENVVQPLLVSTSAITLATETVRSILKIDDIVNTY 298
>29631
          Length = 1257

 Score =  115 bits (289), Expect = 3e-26,   Method: Compositional matrix adjust.
 Identities = 53/140 (37%), Positives = 92/140 (65%)
 Frame = +3

Query: 11  RSTGEAVRSQNVMAAASIANIVKSSFGPVGLDKMLVDDIGDVTITNDGATILKLLEVEHP 70
           R +G  V+  N+ A  +IA+++++  GP  + KML+D +G + +TNDG  IL+ + V+HP
Sbjct: 30  RESGRKVQLGNIAAGKTIADVIRTCLGPKSMLKMLMDPMGGIVMTNDGNAILREINVQHP 209

Query: 71  AAKVLCELADLQDKEVGDGTTSVVIIAAELLKNADELVKQKIHPTSVISGYRLACKEAVR 130
           AAK + E+A  QD+E GDGT SV+I+A E+L  A++ ++Q++HPT +I+ YR A ++ + 
Sbjct: 210 AAKSMIEVARTQDEETGDGTKSVIILAGEVLSVAEQFLEQQMHPTVIIAAYRQALEDTLE 389

Query: 131 YINENLIINTDELGRDCLIN 150
            +   +    D   R+ ++N
Sbjct: 390 VLRTKICTPIDISDRNQMLN 449

 Score = 48.1 bits (113), Expect = 9e-06,   Method: Compositional matrix adjust.
 Identities = 25/66 (37%), Positives = 41/66 (62%)
 Frame = +3

Query: 355  RICDDELILIKNTKARTSASIILRGANDFMCDEMERSLHDALCVVKRVLELKSVVPGGGA 414
            +I DD    + + K+  + +I+LRGA+  +  E+ER+L DA+ V + V+    + PGGGA
Sbjct: 1047 KIGDDYFTFLVDCKSPKACTILLRGASKDILAEVERNLQDAMNVARNVMIDPHLCPGGGA 1226

Query: 415  VEAALS 420
             E AL+
Sbjct: 1227 SEMALA 1244
>33770
          Length = 484

 Score = 92.0 bits (227), Expect = 6e-19,   Method: Compositional matrix adjust.
 Identities = 63/154 (40%), Positives = 94/154 (61%), Gaps = 1/154 (0%)
 Frame = +1

Query: 50  GDVTITNDGATILKLLEVEHPAAKVLCELADLQDKEVGDGTTSVVIIAAELLKNADELVK 109
           GDVTITNDGATILK ++V HPAAK+L EL+  QD E GDGTT+VV++A  LL  + +L+ 
Sbjct: 22  GDVTITNDGATILKQMQVLHPAAKMLVELSKAQDIEXGDGTTTVVVLAGSLLDASAKLLA 201

Query: 110 QKIHPTSVISGYRLACKEAVRYINENLIINTDELG-RDCLINAAKTSMSSKIIGINGDYF 168
           + IHPT +   ++ A  + V  ++   ++   EL  R+ L+++A TS++SK++       
Sbjct: 202 KGIHPTMISEAFQKAASKCVELLDG--MVKPLELSDRESLLSSASTSLNSKVVSQYSSML 375

Query: 169 ANMVVDAVLAVKYTDARGQPRYPVNSVNILKAHG 202
           A + VDAVL  K  D        +  + I+K  G
Sbjct: 376 APIAVDAVL--KVIDPATATNVDLKDIKIIKKLG 471
>30661
          Length = 380

 Score = 58.9 bits (141), Expect = 5e-09,   Method: Composition-based stats.
 Identities = 33/98 (33%), Positives = 52/98 (53%)
 Frame = +3

Query: 341 EVTMLGQAEEVVQERICDDELILIKNTKARTSASIILRGANDFMCDEMERSLHDALCVVK 400
           E T LGQ + + +  I +D+LI         + +I+LRGA   + DE  RSLHDALCV+ 
Sbjct: 63  EKTKLGQCDLIEEVMIGEDKLIKFSGVALGEACTIVLRGATQQILDEAXRSLHDALCVLS 242

Query: 401 RVLELKSVVPGGGAVEAALSIYLENYATSMGSREQLAI 438
           + ++    V GGG  E  ++  +   A     +E +A+
Sbjct: 243 QTVKETRTVYGGGCSEMLMAEAVSQLAAKTPGKEAIAM 356
>25854
          Length = 800

 Score = 55.5 bits (132), Expect = 6e-08,   Method: Compositional matrix adjust.
 Identities = 30/45 (66%), Positives = 35/45 (77%)
 Frame = +3

Query: 510 KVKSLKFATEAAITILRIDDLIKLHPESKDDKHGSYENAVHSGAL 554
           KVKSLKFATEAAITILRIDD+IKL  + +  K  SY +AV +G L
Sbjct: 3   KVKSLKFATEAAITILRIDDMIKLVSQEQGGK--SYSDAVRAGEL 131
>17249
          Length = 909

 Score = 52.8 bits (125), Expect = 4e-07,   Method: Compositional matrix adjust.
 Identities = 33/91 (36%), Positives = 48/91 (52%)
 Frame = +3

Query: 441 FARSLLVIPNTLAVNAAQDSTDLVAKLRAFHNEAQVNPERKNLKWIGLDLVHGKPRDNKQ 500
            +R+L VI  TL  N   ++   +  LRA H + Q N       W G+D   G   D  +
Sbjct: 3   ISRALEVISRTLIQNCGANTIRTLTALRAKHAQGQKNT------W-GIDGNTGNIVDMAE 161

Query: 501 AGVFEPTIVKVKSLKFATEAAITILRIDDLI 531
            G++EP  VK++  K A E AI +LRIDD++
Sbjct: 162 FGIWEPLSVKLQVYKTACETAILLLRIDDIV 254
>31574
          Length = 859

 Score = 29.6 bits (65), Expect = 3.6,   Method: Compositional matrix adjust.
 Identities = 39/148 (26%), Positives = 59/148 (39%), Gaps = 1/148 (0%)
 Frame = -3

Query: 53  TITNDGATILK-LLEVEHPAAKVLCELADLQDKEVGDGTTSVVIIAAELLKNADELVKQK 111
           T  ND A  L       HP AK +C+LA     E+     S + +   L K  D L+   
Sbjct: 857 TFDNDFARALPAYTAFRHPDAKAMCDLAVYNYIEMRSSVNSPLFL---LRKKVDYLL-NA 690

Query: 112 IHPTSVISGYRLACKEAVRYINENLIINTDELGRDCLINAAKTSMSSKIIGINGDYFANM 171
           + P+  I  Y       +RY               C+ N A      KI+ + G     M
Sbjct: 689 LFPSLWIPLYTSVSFSRMRY-------------HQCIANRA---WQDKILTMIGWGTTGM 558

Query: 172 VVDAVLAVKYTDARGQPRYPVNSVNILK 199
           +   + A+ YT  RGQ    VN++++L+
Sbjct: 557 LGACLAALLYTQ-RGQ----VNNISVLE 489
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|29789199|ref|NP_076068.1| importin 5 [Mus musculus]
         (1097 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

04970                                                                 190   1e-61
12577                                                                 209   6e-54
04288                                                                 116   5e-26
05045                                                                  60   4e-09
09672                                                                  45   2e-04
26296                                                                  31   2.9  
37372                                                                  29   9.7  
>04970
          Length = 2440

 Score =  190 bits (482), Expect(3) = 1e-61,   Method: Compositional matrix adjust.
 Identities = 90/177 (50%), Positives = 123/177 (69%)
 Frame = -1

Query: 919  PEVRQAAAYGLGVMAQFGGDNYRPFCTDALPLLVRVIQAPEAKTKENVNATENCISAVGK 978
            PEVRQAAAYG+GVM QFGG  Y   C + +P LV VI+ P++K  EN+NATEN ISAV K
Sbjct: 2281 PEVRQAAAYGVGVMGQFGGPVYADICPECVPRLVSVIEHPDSKQPENINATENAISAVVK 2102

Query: 979  IMKFKPDCVNVEEVLPHWLSWLPLHEDKEEAVQTFSYLCDLIESNHPIVLGPNNTNLPKI 1038
            I K+    VNV++++P  + WLP+ ED +EAV  + Y+CDL+E+NHP +LG N  NLP  
Sbjct: 2101 ICKYNGSKVNVDDIIPRLMHWLPVSEDVDEAVHIYDYVCDLLEANHPGILGENGANLPHA 1922

Query: 1039 FSIIAEGEMHEAIKHEDPCAKRLANVVRQVQTSGGLWTECIAQLSPEQQAAIQELLN 1095
            FSI+A   ++E ++      KRL N+VRQ+QT+  ++  C+AQ S EQQ A+ E L+
Sbjct: 1921 FSILASAVINETLEXSSDVYKRLINIVRQIQTNEQMFAACLAQCSLEQQRALSEALS 1751

 Score = 62.0 bits (149), Expect(3) = 1e-61,   Method: Composition-based stats.
 Identities = 21/43 (48%), Positives = 29/43 (67%)
 Frame = -3

Query: 867  LIVNLICPQRPWPDRQWGLCIFDDIVEHCSPASFKYAEYFISP 909
            L+V ++   RPW D+QW LC++DD++EHC P S  Y  Y  SP
Sbjct: 2435 LLVKMLSQDRPWADKQWALCVWDDVLEHCGPVSANYQNYSCSP 2307

 Score = 25.8 bits (55), Expect(3) = 1e-61,   Method: Composition-based stats.
 Identities = 9/15 (60%), Positives = 12/15 (80%)
 Frame = -2

Query: 904  EYFISPMLQYVCDNS 918
            E F+ PM++YV DNS
Sbjct: 2325 ELFLQPMVEYVTDNS 2281
>12577
          Length = 530

 Score =  209 bits (531), Expect = 6e-54,   Method: Compositional matrix adjust.
 Identities = 99/176 (56%), Positives = 135/176 (76%), Gaps = 1/176 (0%)
 Frame = +3

Query: 692 LKEGFVEYTEQVVKLMVPLLKFYFHDGVRVAAAESMPLLLECARVRGPEYLTQMW-HFMC 750
           LKE F EY+E+VVK+MVPLLKFYFHD VR+AA+ES+P LLECA +RG  Y++ MW +++C
Sbjct: 3   LKEVFAEYSEEVVKIMVPLLKFYFHDDVRIAASESLPYLLECAGIRGEVYVSDMWRNYIC 182

Query: 751 DALIKAIGTEPDSDVLSEIMHSFAKCIEVMGDGCLNNEHFEELGGILKAKLEEHFKNQEL 810
             L+KAI  EP++ VL E ++SFAKC+E  G GCL+    E L  +L   L++HF+ Q  
Sbjct: 183 PNLLKAIEIEPETSVLPEHLNSFAKCVEKXGRGCLSEADMESLVTMLNRLLQKHFERQAE 362

Query: 811 RQVKRQDEDYDEQVEESLQDEDDNDVYILTKVSDILHSIFSSYKEKVLPWFEQLLP 866
           RQ KR+DEDYD+ VEESL +EDD DVYIL+K++DILHS F ++K+  LP +E+++P
Sbjct: 363 RQEKRKDEDYDDVVEESLMEEDDEDVYILSKIADILHSFFGTHKDSFLPVYEKIMP 530
>04288
          Length = 1741

 Score =  116 bits (290), Expect = 5e-26,   Method: Compositional matrix adjust.
 Identities = 53/118 (44%), Positives = 79/118 (66%)
 Frame = -3

Query: 978  KIMKFKPDCVNVEEVLPHWLSWLPLHEDKEEAVQTFSYLCDLIESNHPIVLGPNNTNLPK 1037
            KI K+    VNV++++P  + WLP+ ED +EAV  + Y+CDL+E+NHP +LG N  NLP 
Sbjct: 1106 KICKYNGSKVNVDDIIPRLMHWLPVSEDVDEAVHIYDYVCDLLEANHPGILGENGANLPH 927

Query: 1038 IFSIIAEGEMHEAIKHEDPCAKRLANVVRQVQTSGGLWTECIAQLSPEQQAAIQELLN 1095
             FSI+A   ++E ++      KRL N+VRQ+QT+  ++  C+AQ S EQQ A+ E L+
Sbjct: 926  AFSILASAVINETLEVSSDVYKRLINIVRQIQTNEQMFAACLAQCSLEQQRALSEALS 753
>05045
          Length = 2700

 Score = 60.5 bits (145), Expect = 4e-09,   Method: Compositional matrix adjust.
 Identities = 41/185 (22%), Positives = 83/185 (44%)
 Frame = +1

Query: 859  PWFEQLLPLIVNLICPQRPWPDRQWGLCIFDDIVEHCSPASFKYAEYFISPMLQYVCDNS 918
            P+F   L  ++  +       ++ + +    +++E     +  + +      L+ V +  
Sbjct: 310  PFFSSFLTDLLKRLKQTSSTAEKSFAVGTLAEVIESIGETTIAFVDTLYPVFLRMVKEED 489

Query: 919  PEVRQAAAYGLGVMAQFGGDNYRPFCTDALPLLVRVIQAPEAKTKENVNATENCISAVGK 978
             EVR  A + LG++A  GG+       D L LL+ +I       +EN    +N  +A+ +
Sbjct: 490  DEVRSNAVFALGMLAANGGEKMIARHGDILKLLLEMISK-----EENGRVMDNMCAAICR 654

Query: 979  IMKFKPDCVNVEEVLPHWLSWLPLHEDKEEAVQTFSYLCDLIESNHPIVLGPNNTNLPKI 1038
            ++      + +E ++P  +  LPL ED EE    F+ L  L + N+  V+     +LP +
Sbjct: 655  MVWVNAANLPLEYIVPTVVQCLPLKEDFEENTTVFTCLLKLYQDNNAQVIA----HLPTL 822

Query: 1039 FSIIA 1043
              I++
Sbjct: 823  LQIVS 837
>09672
          Length = 1963

 Score = 45.1 bits (105), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 25/73 (34%), Positives = 43/73 (58%), Gaps = 1/73 (1%)
 Frame = -2

Query: 355  VLPMIKEHIMQMLQNPDWKYRHAGLMALSAIGEGC-HQQMEGILNEIVNFVLLFLQDPHP 413
            VLP +KE+I    ++ DW+YR A +MA  +I EG   ++++ I+ + +  ++  L DP  
Sbjct: 1911 VLPFVKENI----RHADWRYRDAAVMAFGSILEGPDSEKLKPIVEQAMPMLIELLTDPSV 1744

Query: 414  RVRYAACNAVGQM 426
             VR  A   VG++
Sbjct: 1743 VVRDTAAWTVGRV 1705
>26296
          Length = 856

 Score = 30.8 bits (68), Expect = 2.9,   Method: Compositional matrix adjust.
 Identities = 23/93 (24%), Positives = 43/93 (46%)
 Frame = -3

Query: 961  KTKENVNATENCISAVGKIMKFKPDCVNVEEVLPHWLSWLPLHEDKEEAVQTFSYLCDLI 1020
            + K N     +CIS    I +     + ++E +P  L+W      K+E    F  L D++
Sbjct: 764  RGKLNAKDQFSCISGTNDIKELAKGAIFIQECIPENLAW------KQE---LFKKLDDVV 612

Query: 1021 ESNHPIVLGPNNTNLPKIFSIIAEGEMHEAIKH 1053
            +SN  I+    +T LP +F+   + + +  + H
Sbjct: 611  DSNT-ILSSSTSTFLPSLFTANLKHKHNTVVSH 516
>37372
          Length = 790

 Score = 29.3 bits (64), Expect = 9.7,   Method: Composition-based stats.
 Identities = 17/71 (23%), Positives = 39/71 (54%)
 Frame = -1

Query: 201 ILANEHNVALFKHFADLLPGFLQAVNDSCYQNDDSVLKSLVEIADTVPKYLRPHLEATLQ 260
           +++N ++V  F+H+  +LP  LQ   + C+    S+ + +  +  ++  ++ P L+ +L 
Sbjct: 790 VISNSNDVIFFRHYKSILP--LQCFTEMCFV*CPSL*RRIHPLFLSIHLFINPTLQHSL- 620

Query: 261 LSLKLCGDTNL 271
           LS  L  + N+
Sbjct: 619 LSFSLIVNMNV 587
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|51093867|ref|NP_076014.1| carbamoyl-phosphate
synthetase 2, aspartate transcarbamylase, and dihydroorotase [Mus
musculus]
         (2225 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

08342                                                                 235   2e-61
31736                                                                 108   9e-49
18882                                                                  71   4e-22
15060                                                                  37   0.082
27443                                                                  33   1.6  
01707                                                                  32   3.8  
>08342
          Length = 1799

 Score =  235 bits (599), Expect = 2e-61,   Method: Compositional matrix adjust.
 Identities = 131/304 (43%), Positives = 181/304 (59%), Gaps = 9/304 (2%)
 Frame = -2

Query: 1150 AISEHVENAGVHSGDATLVTPPQDITPKTLERIKAIVHAVGQELQVTGPFNLQLIAKDDQ 1209
            A+ EHVENAGVHSGDATL+ P Q IT + +  IK     +  + ++TGPFN+Q + KD  
Sbjct: 1783 AMCEHVENAGVHSGDATLMLPTQTITEEAINTIKEATAKIASKFEITGPFNIQFLVKDSD 1604

Query: 1210 LKVIECNVRVSRSFPFVSKTLGVDLVALATRIIMGEKVEPVGLMT------GSGVVGVKV 1263
            ++VIE N+R SRS PFVSKT+G D +A ATR++MG  V+   L T       +  VG+K 
Sbjct: 1603 VRVIELNLRASRSCPFVSKTIGTDFIATATRVMMGMPVDTTQLPTLDNPRNPTDYVGIKA 1424

Query: 1264 PQFSFSRLAGADVVLGVEMTSTGEVAGFGESRCEAYLKAMLSTGFKIPEK--NILLTIGS 1321
            P FS+ RL  AD +L  EM STGEVA FG ++  A+LKAM+S GFK+P    NI++ + S
Sbjct: 1423 PMFSWPRLTDADPILKCEMASTGEVACFGRTKYTAFLKAMMSAGFKLPRPGGNIMVGVQS 1244

Query: 1322 YKNKSELLPTVRLLESLGYSLYASLGTADFYTEHGVKVTAVDWHFEEAVDGECPPQRSIL 1381
                  +LP  + L +LGY++YA+  TA +  +H ++   V W   E  D E P    I+
Sbjct: 1243 -SFLPHILPLTKRLHTLGYNIYATEKTAQYLNKHYIQAQTVSWSLLEDADSEHPKATKII 1067

Query: 1382 DQLAENH-FELVINLSMRGAGGRRLSSFVTKGYRTRRLAADFSVPLIIDIKCTKLFVEAL 1440
                E+H  +LVINL        + + ++   Y  RR A D +VPLI + +  KLFVEAL
Sbjct: 1066 ----EDHGIDLVINLP------NQKTEYLKDNYLIRRSAIDSAVPLITNFEVVKLFVEAL 917

Query: 1441 GQIG 1444
               G
Sbjct: 916  DYTG 905

 Score = 55.5 bits (132), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 38/167 (22%), Positives = 69/167 (41%), Gaps = 5/167 (2%)
 Frame = -2

Query: 619  ENLDPLGIHTGESIVVAPSQTLNDREYQLLRRTAIKVTQHLGIVGECNVQYALNPESEQY 678
            E+++  G+H+G++ ++ P+QT+ +     ++    K+     I G  N+Q+ +  +    
Sbjct: 1774 EHVENAGVHSGDATLMLPTQTITEEAINTIKEATAKIASKFEITGPFNIQFLV--KDSDV 1601

Query: 679  YIIEVNXXXXXXXXXXXXXTGYPLAYVAAKLALGIP-----LPELRNSVTGGTAAFEPSL 733
             +IE+N              G      A ++ +G+P     LP L N             
Sbjct: 1600 RVIELNLRASRSCPFVSKTIGTDFIATATRVMMGMPVDTTQLPTLDNP--------RNPT 1445

Query: 734  DYCVVKIPRWDLSKFLRVSTKIGSCMKSVGEVMGIGRSFEEAFQKAL 780
            DY  +K P +   +       +   M S GEV   GR+   AF KA+
Sbjct: 1444 DYVGIKAPMFSWPRLTDADPILKCEMASTGEVACFGRTKYTAFLKAM 1304
>31736
          Length = 539

 Score =  108 bits (270), Expect(3) = 9e-49,   Method: Compositional matrix adjust.
 Identities = 55/75 (73%), Positives = 62/75 (82%)
 Frame = +2

Query: 1078 CHTVGYPCVVRPSYVLSGAAMNVAYTDGDLERFLSSAAAVSKEHPVVISKFIQEAKEIDV 1137
            C  VG PC+VRPSYVLSGAAMNVA++  DLE FL+ A+ VSKEHPVVISKFI EAKEIDV
Sbjct: 314  CQDVGLPCLVRPSYVLSGAAMNVAHSAVDLENFLTQASLVSKEHPVVISKFILEAKEIDV 493

Query: 1138 DAVACDGIVSAIAIS 1152
            DAVA DG V  +A+S
Sbjct: 494  DAVASDGEVICMAVS 538

 Score = 75.1 bits (183), Expect(3) = 9e-49,   Method: Composition-based stats.
 Identities = 36/71 (50%), Positives = 45/71 (63%)
 Frame = +1

Query: 1007 NPEGVILSMGGQLPNNMAMALHRQQCRVLGTSPEAIDSAENRFKFSRLLDTIGISQPQWR 1066
            NP     +   + P          +C  LGTSP+ ID+AENRFKFSR+LDT+GISQP+W+
Sbjct: 100  NPRASFCAWEARPPTTSPWISTGSRCPFLGTSPDMIDNAENRFKFSRMLDTMGISQPRWK 279

Query: 1067 ELSDLESARQF 1077
            ELS  ESA  F
Sbjct: 280  ELSTTESALSF 312

 Score = 51.6 bits (122), Expect(3) = 9e-49,   Method: Composition-based stats.
 Identities = 20/20 (100%), Positives = 20/20 (100%)
 Frame = +2

Query: 974 YNPETVSTDYDMCDRLYFDE 993
           YNPETVSTDYDMCDRLYFDE
Sbjct: 2   YNPETVSTDYDMCDRLYFDE 61

 Score = 68.6 bits (166), Expect = 3e-11,   Method: Composition-based stats.
 Identities = 28/41 (68%), Positives = 33/41 (80%)
 Frame = +3

Query: 996  FEVVMDIYELENPEGVILSMGGQLPNNMAMALHRQQCRVLG 1036
            FEVVMD+Y +E PEG+IL MGGQ PNN+AM LHRQQ  + G
Sbjct: 66   FEVVMDVYNMEKPEGIILCMGGQAPNNIAMDLHRQQVSIFG 188
>18882
          Length = 447

 Score = 66.2 bits (160), Expect(2) = 4e-22,   Method: Composition-based stats.
 Identities = 30/49 (61%), Positives = 38/49 (77%)
 Frame = -2

Query: 1377 QRSILDQLAENHFELVINLSMRGAGGRRLSSFVTKGYRTRRLAADFSVP 1425
            Q +I   LAEN F+LVINL +R +GG R SSFVT+GY+TRR+A D+ VP
Sbjct: 446  QSTIAHYLAENMFDLVINLPLRVSGGYRASSFVTQGYKTRRMAVDYCVP 300

 Score = 58.9 bits (141), Expect(2) = 4e-22,   Method: Composition-based stats.
 Identities = 22/41 (53%), Positives = 34/41 (82%)
 Frame = -3

Query: 1425 PLIIDIKCTKLFVEALGQIGPAPPLKVHVDCMTSQKLVRLP 1465
            PL+ D+KCTK+F+EAL  I   PP+K H+DC++S++++RLP
Sbjct: 301  PLLTDVKCTKMFIEALRLIKGQPPMKSHIDCISSKRVLRLP 179

 Score = 70.9 bits (172), Expect = 6e-12,   Method: Composition-based stats.
 Identities = 29/57 (50%), Positives = 41/57 (71%)
 Frame = -1

Query: 1523 AEAGARCDFTLFLGASSENAGTLGAVAGSAAGLKLYLNETFSELRLDSVAQWMEHFE 1579
            A  GA CD+ L+LGAS+ N   L A+A  +  LK+YLNETF+ L++D ++ WM+HFE
Sbjct: 174  ARQGAHCDYGLYLGASNTNFTVLPAMAAQSVALKMYLNETFTTLKMDDISVWMKHFE 4
>15060
          Length = 935

 Score = 37.0 bits (84), Expect = 0.082,   Method: Compositional matrix adjust.
 Identities = 32/142 (22%), Positives = 64/142 (45%), Gaps = 4/142 (2%)
 Frame = -2

Query: 581 AFAHTSQVLIDKSLKGWKEIEYEVVRDAYGNCVTV----CNMENLDPLGIHTGESIVVAP 636
           AF   S + I+K ++  + IE +++ D  GN + +    C+++          + + +AP
Sbjct: 607 AFGDGS-LFIEKFIERPRHIEVQLLGDRTGNVIHLYERDCSVQR------RHQKVVEIAP 449

Query: 637 SQTLNDREYQLLRRTAIKVTQHLGIVGECNVQYALNPESEQYYIIEVNXXXXXXXXXXXX 696
           +  L+      +   A+++ + +G      V++ L+ ++ QYY IEVN            
Sbjct: 448 APQLDSEVRTKMANDAVRLAKFVGYENAGTVEFLLD-KNGQYYFIEVNARLQVEHTVTEQ 272

Query: 697 XTGYPLAYVAAKLALGIPLPEL 718
            TG  L     ++A G  L +L
Sbjct: 271 VTGVDLVQAQIRIAEGKTLSDL 206
>27443
          Length = 454

 Score = 32.7 bits (73), Expect = 1.6,   Method: Composition-based stats.
 Identities = 12/33 (36%), Positives = 21/33 (63%)
 Frame = +3

Query: 1001 DIYELENPEGVILSMGGQLPNNMAMALHRQQCR 1033
            D+Y LE+PE V+++  G    +  + L+R+ CR
Sbjct: 18   DVYPLESPEIVMITQTGHFRCHXGLCLYRKHCR 116
>01707
          Length = 757

 Score = 31.6 bits (70), Expect = 3.8,   Method: Compositional matrix adjust.
 Identities = 22/83 (26%), Positives = 35/83 (42%), Gaps = 1/83 (1%)
 Frame = +1

Query: 63  PSDEEDEFGLSKWFESSEIHVAGLVVGECCPTPSHWSANCTLHEWLQQRGI-PGLQGVDT 121
           P DE  ++  ++W+ + E+ V     G   P    W+  C   E L  + + PG   VD 
Sbjct: 520 PGDEYTDYVATRWYRAPELLVGDTQYG---PPVDVWAIGCVFAELLTGQALWPGRSDVDQ 690

Query: 122 RELTKKLREQGSLLGKLVQKGTE 144
             L +K       LG L+ +  E
Sbjct: 691 LHLIRK------TLGDLIPRHIE 741
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|71274170|ref|NP_001025044.1| unc-13 homolog A [Mus
musculus]
         (1797 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

30575                                                                 190   2e-61
11353                                                                  70   6e-12
22804                                                                  69   2e-11
25445                                                                  54   7e-07
19361                                                                  51   3e-06
29179                                                                  47   6e-05
13896                                                                  46   1e-04
35187                                                                  43   0.001
36305                                                                  40   0.008
07591                                                                  35   0.35 
30040                                                                  35   0.36 
11391                                                                  33   0.71 
01494                                                                  32   2.6  
15228                                                                  31   5.9  
25342                                                                  30   6.1  
27478                                                                  30   8.2  
>30575
          Length = 456

 Score =  190 bits (482), Expect(2) = 2e-61,   Method: Compositional matrix adjust.
 Identities = 88/115 (76%), Positives = 103/115 (89%)
 Frame = +2

Query: 1046 NFGKERFVKLLDQLHNSLRIDLSMYRNNFPASSPERLQDLKSTVDLLTSITFFRMKVQEL 1105
            NFGKE+FVKLLDQLHNSLRIDLSMYRNNFPAS P R++DLKSTVD LTSITFFRMKVQEL
Sbjct: 2    NFGKEKFVKLLDQLHNSLRIDLSMYRNNFPASDPGRMKDLKSTVDFLTSITFFRMKVQEL 181

Query: 1106 QSPPRASQVVKDCVKACLNSTYEYIFNNCHELYGREYQTDPAKKGEVPPEEQGPS 1160
            QSPPRAS VVKDCV AC+ STY+++F NC+ELY RE+QTDP+++  V  +++GPS
Sbjct: 182  QSPPRASTVVKDCVTACIRSTYKFLFENCYELYQREFQTDPSEQPAV--DQEGPS 340

 Score = 66.6 bits (161), Expect(2) = 2e-61,   Method: Compositional matrix adjust.
 Identities = 28/36 (77%), Positives = 33/36 (91%)
 Frame = +3

Query: 1163 NLDFWSKLITLIVSIIEEDKNSYTPCLNQFPQELNV 1198
            +LDFW KLI L+VS+IEEDKNSYTP L+QFPQ+LNV
Sbjct: 348  SLDFWHKLIVLVVSVIEEDKNSYTPVLSQFPQDLNV 455
>11353
          Length = 454

 Score = 70.5 bits (171), Expect = 6e-12,   Method: Compositional matrix adjust.
 Identities = 27/51 (52%), Positives = 34/51 (66%)
 Frame = +1

Query: 672 PHNFEVWTATTPTYCYECEGLLWGIARQGMRCTECGVKCHEKCQDLLNADC 722
           PH FE +T TTPTYC  C+ LLWG ++ G  C +CG  CH+KCQ L+   C
Sbjct: 139 PHRFEKYTYTTPTYCDFCQQLLWGFSKTGTHCVDCGYNCHDKCQPLVPKTC 291
>22804
          Length = 967

 Score = 68.6 bits (166), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 27/51 (52%), Positives = 34/51 (66%)
 Frame = -3

Query: 672 PHNFEVWTATTPTYCYECEGLLWGIARQGMRCTECGVKCHEKCQDLLNADC 722
           PH FE +T TTPTYC  C+ LLWG ++ G  C +CG  CH+KCQ L+   C
Sbjct: 833 PHRFEKYTYTTPTYCDFCQQLLWGFSKTGTHCVDCGYNCHDKCQPLVPKTC 681
>25445
          Length = 460

 Score = 53.5 bits (127), Expect = 7e-07,   Method: Composition-based stats.
 Identities = 18/46 (39%), Positives = 29/46 (63%)
 Frame = -1

Query: 670 TTPHNFEVWTATTPTYCYECEGLLWGIARQGMRCTECGVKCHEKCQ 715
           T  H F+  T  +PT+C  C  LL+G+  QG++C  C + CH++C+
Sbjct: 406 TNLHKFKAHTYGSPTFCDHCGSLLYGLIHQGLKCDSCDMNCHKRCE 269
>19361
          Length = 685

 Score = 51.2 bits (121), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 18/52 (34%), Positives = 31/52 (59%)
 Frame = -1

Query: 672 PHNFEVWTATTPTYCYECEGLLWGIARQGMRCTECGVKCHEKCQDLLNADCL 723
           PH F+V       +C  C   +WG+  QG++C +CGV+ H+KC + +  +C+
Sbjct: 319 PHVFKVQNFNGLNWCELCANFMWGLIAQGVKCQDCGVQTHKKCSERMPNECM 164
>29179
          Length = 1113

 Score = 47.0 bits (110), Expect = 6e-05,   Method: Compositional matrix adjust.
 Identities = 37/100 (37%), Positives = 51/100 (51%), Gaps = 7/100 (7%)
 Frame = -3

Query: 797 ISITVVCAQGLQAKDKTGSSDPYVTVQVGKTKKR---TKTIYGNLNPVWEENFHFEC--H 851
           +++ ++ A  L AKD TG+SDPYV + +   KK    TK    NLNP W E F FE   H
Sbjct: 493 LTLRIIRAVDLPAKDVTGTSDPYVKILLLPDKKHKLLTKVKKRNLNPHWNECFLFEGWPH 314

Query: 852 NS--SDRIKVRVWDEDDDIKSRVKQRFKRESDDFLGQTII 889
           N      + ++V D D         RF R  DD +G+T +
Sbjct: 313 NKLLEKTLYLQVIDYD---------RFSR--DDPIGETYL 227

 Score = 38.1 bits (87), Expect = 0.030,   Method: Compositional matrix adjust.
 Identities = 30/107 (28%), Positives = 47/107 (43%), Gaps = 1/107 (0%)
 Frame = -3

Query: 1641 VTVKVVAANDLKWQ-TSGIFRPFIEVNIVGPQLSDKKRKFATKSKNNSWAPKYNESFQFS 1699
            +T++++ A DL  +  +G   P++++ +    L DKK K  TK K  +  P +NE F F 
Sbjct: 493  LTLRIIRAVDLPAKDVTGTSDPYVKILL----LPDKKHKLLTKVKKRNLNPHWNECFLFE 326

Query: 1700 LSADAGPECYELQVCVKDYCFAREDRTVGLAVLQLRELAQRGSAACW 1746
                       L + V DY     D  +G   L L E+    S   W
Sbjct: 325  GWPHNKLLEKTLYLQVIDYDRFSRDDPIGETYLPLNEIDLSQSPVSW 185

 Score = 34.7 bits (78), Expect = 0.36,   Method: Composition-based stats.
 Identities = 14/28 (50%), Positives = 22/28 (78%)
 Frame = -1

Query: 795 AKISITVVCAQGLQAKDKTGSSDPYVTV 822
            ++++ V+ A+ L+AKD TGSSDPYV +
Sbjct: 105 GRLTVIVMKAKELKAKDITGSSDPYVKI 22
>13896
          Length = 827

 Score = 46.2 bits (108), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 32/89 (35%), Positives = 44/89 (49%)
 Frame = +2

Query: 799 ITVVCAQGLQAKDKTGSSDPYVTVQVGKTKKRTKTIYGNLNPVWEENFHFECHNSSDRIK 858
            TV+ A+ L +K K+G++D YVT+Q+GK K +T TI    NP W E       +    I+
Sbjct: 164 FTVLRARNLISKGKSGNNDVYVTIQLGKEKYQTSTIRNAHNPEWFEECDLPIPHLHSEIE 343

Query: 859 VRVWDEDDDIKSRVKQRFKRESDDFLGQT 887
           V V+                 SDDFLG T
Sbjct: 344 VSVYHXG------------VLSDDFLGYT 394
>35187
          Length = 593

 Score = 42.7 bits (99), Expect = 0.001,   Method: Composition-based stats.
 Identities = 23/85 (27%), Positives = 34/85 (40%), Gaps = 6/85 (7%)
 Frame = -3

Query: 644 STLNNEELKNHVYKKTLQALIYPISCTTP------HNFEVWTATTPTYCYECEGLLWGIA 697
           S+   EE       +  +A + P     P      H F   T   PTYC+ C  +LWG+ 
Sbjct: 420 SSATGEEADGLAMAEETEAGLSPSDSPVPPDHGHGHFFTKKTFHKPTYCHHCTDILWGLI 241

Query: 698 RQGMRCTECGVKCHEKCQDLLNADC 722
             G  C  C    H++C   + + C
Sbjct: 240 GVGYVCEVCNFVVHDRCMKTVVSPC 166
>36305
          Length = 586

 Score = 40.0 bits (92), Expect = 0.008,   Method: Composition-based stats.
 Identities = 27/82 (32%), Positives = 37/82 (45%), Gaps = 1/82 (1%)
 Frame = -1

Query: 814 GSSDPYVTVQVGKTKKRTKTIYGNLNPVWEENFHFECHNSSDRI-KVRVWDEDDDIKSRV 872
           G SDPY  V VG    +TK I   + P W E F F       +I K+ + D+D   K   
Sbjct: 583 GKSDPYTVVTVGAQTFKTKVIDDTVEPRWNEVFEFVIDERDGQILKLNISDKDPGNK--- 413

Query: 873 KQRFKRESDDFLGQTIIEVRTL 894
                   DD LG T +++ T+
Sbjct: 412 --------DDPLGSTTMDISTI 371

 Score = 37.4 bits (85), Expect = 0.056,   Method: Compositional matrix adjust.
 Identities = 23/76 (30%), Positives = 38/76 (50%), Gaps = 2/76 (2%)
 Frame = -3

Query: 779 MKAVKQSVLDGTSKWSAKISITVVCAQGLQAKDKTG--SSDPYVTVQVGKTKKRTKTIYG 836
           M+ V+   +D  S  +A + + +  A  L  +DK       PYVT+++G+T++ +     
Sbjct: 254 MEQVRDEGVDEDSVHAALLVVNLDSALDL-PRDKKSLLEPSPYVTLRLGQTEQESGIRNA 78

Query: 837 NLNPVWEENFHFECHN 852
              P WEENF F   N
Sbjct: 77  TTEPRWEENFRFFVAN 30
>07591
          Length = 796

 Score = 34.7 bits (78), Expect = 0.35,   Method: Compositional matrix adjust.
 Identities = 31/98 (31%), Positives = 39/98 (39%), Gaps = 10/98 (10%)
 Frame = +2

Query: 804 AQGLQAKDKTGSSDPYVTVQVGKTK------KRTKTIYGNLNPVW---EENFHFEC-HNS 853
           A+ L  KD  G SDPY+ V    +        RT+ +  NLNP W   E +    C  N 
Sbjct: 479 AKKLDKKDFLGKSDPYLEVLRATSDGSWQMVHRTEVVKNNLNPSWRPFELSMQTLCGGNH 658

Query: 854 SDRIKVRVWDEDDDIKSRVKQRFKRESDDFLGQTIIEV 891
              IK  V+D D D        F     D L  +  EV
Sbjct: 659 QQNIKFDVYDWDSDGSHDYIGGFTTTLQDMLKASAQEV 772
>30040
          Length = 652

 Score = 34.7 bits (78), Expect = 0.36,   Method: Composition-based stats.
 Identities = 19/60 (31%), Positives = 33/60 (55%), Gaps = 5/60 (8%)
 Frame = -3

Query: 794 SAKISITVVCAQGLQAKDKTGSSDPYVTVQV---GKTKKRTKTIY--GNLNPVWEENFHF 848
           + ++++ ++ A+ L+      S+DP+V V +   GK  KR KT     ++NPVW E   F
Sbjct: 620 AERLTVVLMKAKDLKMSTSHPSADPFVRVSLLVEGKKVKRKKTSVRRASINPVWNEALAF 441
>11391
          Length = 1866

 Score = 33.5 bits (75), Expect = 0.71,   Method: Composition-based stats.
 Identities = 18/52 (34%), Positives = 29/52 (55%), Gaps = 1/52 (1%)
 Frame = +2

Query: 123  CPYSVKKAKFDGAQEKFNTYVTLKVQNVKST-TIAVRGSQPSWEQDFMLSHK 173
            CP+ V + KF    +  +TY+ L V+NVKS+ +    GS P++   F   +K
Sbjct: 1415 CPFMVTRFKFSNPAKF*STYIFLNVRNVKSSFSYRFNGSFPTYSVWFSFPYK 1570
>01494
          Length = 2122

 Score = 32.0 bits (71), Expect = 2.6,   Method: Compositional matrix adjust.
 Identities = 26/77 (33%), Positives = 40/77 (51%), Gaps = 8/77 (10%)
 Frame = +1

Query: 797  ISITVVCAQGLQAKDKTGSSDPYVTVQV-----GKTKKRTKTIYGN-LNPVWEENFHFE- 849
            +++T+V A+ L  K   G + P+V ++V        K +T T   N LNPVW EN  F+ 
Sbjct: 1165 LTLTIVGARHL-VKSGRGIASPFVEIEVTGXECDNQKFKTGTRVDNGLNPVWNENCVFDV 1341

Query: 850  -CHNSSDRIKVRVWDED 865
             C   +  ++  V DED
Sbjct: 1342 LCPEMA-LLRFAVMDED 1389
>15228
          Length = 895

 Score = 30.8 bits (68), Expect = 5.9,   Method: Compositional matrix adjust.
 Identities = 21/64 (32%), Positives = 39/64 (60%), Gaps = 5/64 (7%)
 Frame = +3

Query: 1049 KERFVKLLDQLHNSLRID-LSMYRNNFPASSPERLQDLKSTVDL----LTSITFFRMKVQ 1103
            +E FV LLD+LHN  +++ +S++ + +PA S    QDL+ +  L     T +  F+  V+
Sbjct: 21   RESFVVLLDELHNKGKLNSMSLWMDLYPAVS----QDLRFSSMLGQSGSTPLDLFKFYVE 188

Query: 1104 ELQS 1107
            +L++
Sbjct: 189  DLKA 200
>25342
          Length = 733

 Score = 30.4 bits (67), Expect = 6.1,   Method: Composition-based stats.
 Identities = 13/40 (32%), Positives = 23/40 (57%)
 Frame = +2

Query: 1237 FKVKWLYNEYVAELPTFKDRVPEYPAWFEPFVIQWLDENE 1276
             K +W++ EYV +L TF+   P Y    +   ++W+ E+E
Sbjct: 215  LKKRWVFLEYVPQL*TFR---PTYFVLIDKIPVEWMGEDE 325
>27478
          Length = 373

 Score = 30.0 bits (66), Expect = 8.2,   Method: Compositional matrix adjust.
 Identities = 22/70 (31%), Positives = 33/70 (47%), Gaps = 9/70 (12%)
 Frame = -3

Query: 1065 IDLSMYRNNFPASSPE---------RLQDLKSTVDLLTSITFFRMKVQELQSPPRASQVV 1115
            I L+M     PAS PE           +DL S  DL+     + M   + QS  +A + +
Sbjct: 236  IQLAMENLKLPASQPEDDLHQPPSDNAEDLDSDDDLVP----YDMSFDKKQSKIKAPKYI 69

Query: 1116 KDCVKACLNS 1125
            +DC++  LNS
Sbjct: 68   RDCMEGLLNS 39
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|7242156|ref|NP_036072.1| lysophospholipase 2 [Mus
musculus]
         (231 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

17646                                                                 230   3e-61
09451                                                                  29   1.6  
02022                                                                  28   4.0  
32518                                                                  28   4.6  
05678                                                                  27   4.8  
06248                                                                  27   5.0  
00474                                                                  27   6.3  
>17646
          Length = 1240

 Score =  230 bits (587), Expect = 3e-61,   Method: Compositional matrix adjust.
 Identities = 113/213 (53%), Positives = 148/213 (69%), Gaps = 1/213 (0%)
 Frame = -3

Query: 14   AATVSGAERETAAVIFLHGLGDTGHSWADALSTIRLPHVKYICPHAPRIPVTLNMKMVMP 73
            AA V   +  TA +IFLHGLGDTGH WAD L  ++  H+K ICPHAP  PVTLN  M MP
Sbjct: 1115 AAVVKPLKDHTATLIFLHGLGDTGHGWADGLQMLKFQHIKCICPHAPIQPVTLNAGMKMP 936

Query: 74   SWFDLMGLSPDAPEDEAGIKKAAENIKALIEHEMKNGIPANRIVLGGFSQGGALSLYTAL 133
            SWFD+ GL P + ED+ GIK+A++ ++ LI++E K+GIP+ RI +GGFSQGGA++LYTAL
Sbjct: 935  SWFDIQGLDPGSEEDKKGIKEASKILQELIDNEKKSGIPSERIFIGGFSQGGAVALYTAL 756

Query: 134  TCPHPLAGIVALSCWLPLHRN-FPQAANGSAKDLAILQCHGELDPMVPVRFGALTAEKLR 192
                P+ G+VALS WLPLH       A+     + +LQCHG  DPMV   +G  T++ L+
Sbjct: 755  NVNKPVGGVVALSTWLPLHSTLLADKASLHNTGVPVLQCHGTHDPMVRFAWGKKTSDFLK 576

Query: 193  TVVTPARVQFKTYPGVMHSSCPQEMAAVKEFLE 225
            ++   A  QFK+Y G+MHSSCP+EM  +K FLE
Sbjct: 575  SLNPNA--QFKSYDGMMHSSCPEEMQDLKVFLE 483

 Score = 30.4 bits (67), Expect = 0.55,   Method: Compositional matrix adjust.
 Identities = 12/45 (26%), Positives = 23/45 (51%), Gaps = 3/45 (6%)
 Frame = +3

Query: 36   TGHSWADALSTIRLPHVKYICPHAPRIPVTLNM---KMVMPSWFD 77
             G    DAL  ++  H++ +CP  PR+  ++     + V+  WF+
Sbjct: 972  NGRVRTDALYVLKFQHLQTVCPAMPRVSQSMQKDEGRCVVLQWFN 1106
>09451
          Length = 1994

 Score = 28.9 bits (63), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 22/64 (34%), Positives = 29/64 (45%), Gaps = 9/64 (14%)
 Frame = -3

Query: 151  LHRNFPQAANGSAKDLAILQCHGELDPMVPVRFGALTAEKL--------RTVVT-PARVQ 201
            L R  P+  N      A L CHG LD MV  ++  L A +L        RT +T P  V 
Sbjct: 1527 LEREAPEFVNSRRIPDAALMCHGTLDGMVRQKWSLLAAIQLFQTQNELSRTSLTSPIEVP 1348

Query: 202  FKTY 205
            F ++
Sbjct: 1347 FTSF 1336
>02022
          Length = 455

 Score = 27.7 bits (60), Expect = 4.0,   Method: Compositional matrix adjust.
 Identities = 14/39 (35%), Positives = 22/39 (56%)
 Frame = +2

Query: 80  GLSPDAPEDEAGIKKAAENIKALIEHEMKNGIPANRIVL 118
           GL+PD PED   + K A +I+  +E   K+     R++L
Sbjct: 305 GLAPDLPEDLYCLIKKAVSIRKHLERNRKDKDAKFRLIL 421
>32518
          Length = 471

 Score = 27.7 bits (60), Expect = 4.6,   Method: Compositional matrix adjust.
 Identities = 9/20 (45%), Positives = 14/20 (70%)
 Frame = +2

Query: 21 ERETAAVIFLHGLGDTGHSW 40
          +  T ++IFLH + DT HS+
Sbjct: 20 QHATKSIIFLHAISDTSHSF 79
>05678
          Length = 1799

 Score = 27.3 bits (59), Expect = 4.8,   Method: Compositional matrix adjust.
 Identities = 33/164 (20%), Positives = 57/164 (34%), Gaps = 29/164 (17%)
 Frame = +2

Query: 3   GNTMSVPLLTDAATVSGAERETAAVIFLHGLGDTGHSWADALSTIRLPHVK--------- 53
           GN ++  +   +   SG  RETA  +++H +    +  A+  + +RL H K         
Sbjct: 731 GNEVNPGVTDPSERGSGFTRETAKPLYVHRVPGDAYDKAEDTAGLRLAHTKKNDPMEYLN 910

Query: 54  --------------YICPHAPRIPVTLNMKMVMPSWFDLMGLSPDAPEDEAGIKKAAENI 99
                         Y+    P +     +      W +L G S    E+     K  +++
Sbjct: 911 MTHPNNHSSTNKDQYLGQQRPDLSHPDRLNRTKTGWQELSGYS----ENNDRFVKVPDDV 1078

Query: 100 KALIEHEM---KNGIPANRIVLG---GFSQGGALSLYTALTCPH 137
           +    H M   ++  P     LG   G  QG     +T  T  H
Sbjct: 1079RRFTTHYMTKFQDDTPQGLSRLGHTRGGVQGQKRDGFTMSTGVH 1210
>06248
          Length = 544

 Score = 27.3 bits (59), Expect = 5.0,   Method: Compositional matrix adjust.
 Identities = 14/39 (35%), Positives = 22/39 (56%)
 Frame = +2

Query: 80  GLSPDAPEDEAGIKKAAENIKALIEHEMKNGIPANRIVL 118
           GL+PD PED   + K A +I+  +E   K+     R++L
Sbjct: 287 GLAPDLPEDLYCLIKKAVSIRKHLERNRKDKDAKFRLIL 403
>00474
          Length = 1697

 Score = 26.9 bits (58), Expect = 6.3,   Method: Compositional matrix adjust.
 Identities = 14/32 (43%), Positives = 16/32 (50%)
 Frame = +2

Query: 118 LGGFSQGGALSLYTALTCPHPLAGIVALSCWL 149
           LG   +GG   L  A TCPHP  G V    W+
Sbjct: 770 LGPV*EGGGNLLLIAFTCPHPKQG*VPTYSWV 865
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|27754065|ref|NP_080714.2| pyrophosphatase [Mus
musculus]
         (289 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

07342                                                                 230   4e-61
12528                                                                 132   4e-54
32839                                                                  44   6e-05
20119                                                                  29   1.7  
14976                                                                  28   4.5  
>07342
          Length = 538

 Score =  230 bits (587), Expect = 4e-61,   Method: Compositional matrix adjust.
 Identities = 106/165 (64%), Positives = 128/165 (77%), Gaps = 2/165 (1%)
 Frame = +1

Query: 4   FSSEERAAPFTLEYRVFLKNEKGQYISPFHDVPIYADK--DVFHMVVEVPRWSNAKMEIA 61
           +S  ER  P TLEYRVF K   G  +SPFHD+P+YAD+     +MVVE+PRW+NAKMEI 
Sbjct: 43  YSIVERGQPNTLEYRVFFKGPSGNIVSPFHDIPLYADQVSKTCNMVVEIPRWTNAKMEIN 222

Query: 62  TKDPLNPIKQDVKKGKLRYVANLFPYKGYIWNYGAIPQTWEDPGHSDKHTGCCGDNDPID 121
            ++  NPIKQDVKKGKLRYV N+FP+ GYIWNYGA+PQTWEDP H D+ T   GDNDP+D
Sbjct: 223 KEEKFNPIKQDVKKGKLRYVKNIFPHHGYIWNYGALPQTWEDPKHVDQETKTAGDNDPLD 402

Query: 122 VCEIGSKVCARGEIIRVKVLGILAMIDEGETDWKVIAINVDDPDA 166
           VCEIG K   RG +I+VK+LG + +IDEGETDWK+IAI+V DP A
Sbjct: 403 VCEIGHKXQERGAVIQVKILGTMLLIDEGETDWKIIAIDVTDPLA 537
>12528
          Length = 928

 Score =  132 bits (332), Expect(2) = 4e-54,   Method: Compositional matrix adjust.
 Identities = 57/86 (66%), Positives = 70/86 (81%)
 Frame = +3

Query: 83  NLFPYKGYIWNYGAIPQTWEDPGHSDKHTGCCGDNDPIDVCEIGSKVCARGEIIRVKVLG 142
           N+FP+ GYIWNYGA+PQTWEDP H D+ T   GDNDP+DVCEIG K+  RG +I+VK+LG
Sbjct: 153 NIFPHHGYIWNYGALPQTWEDPKHVDQETKTAGDNDPLDVCEIGHKIQERGAVIQVKILG 332

Query: 143 ILAMIDEGETDWKVIAINVDDPDAAN 168
            + +IDEGETDWK+IAI+V DP A N
Sbjct: 333 TMLLIDEGETDWKIIAIDVTDPLAEN 410

 Score = 96.7 bits (239), Expect(2) = 4e-54,   Method: Compositional matrix adjust.
 Identities = 53/117 (45%), Positives = 70/117 (59%), Gaps = 2/117 (1%)
 Frame = +2

Query: 171 DISDVERLKPGYLEATVDWFRRYKVPDGKPENEFAFNAEFKNKDFAVDIIKSTHDYWKAL 230
           DI DVER  PG+L+AT DWFR YKVPDGKPENE  +  + K++ FAVDI+   +  WK L
Sbjct: 416 DIDDVEREMPGFLKATYDWFRFYKVPDGKPENEVHWGGKCKDRKFAVDIVDEANGLWKKL 595

Query: 231 VTKKTDGKGISCMNTTVSESPFKCDPDAAKAIVDALPPPCESACSLPTD--VDKWFH 285
           +   +D   +SC NT V   P    P+ A++ V     P   A   PTD  V+KW++
Sbjct: 596 MQNPSDSADVSCSNTCVKGCPDTVSPENAESHVKQSAEPGAPA---PTDQEVNKWYY 757
>32839
          Length = 294

 Score = 44.3 bits (103), Expect = 6e-05,   Method: Compositional matrix adjust.
 Identities = 21/31 (67%), Positives = 25/31 (80%)
 Frame = -2

Query: 133 GEIIRVKVLGILAMIDEGETDWKVIAINVDD 163
           G  I VKVLG L +IDEGETDWK++AI+V D
Sbjct: 95  GRGIEVKVLGTLLLIDEGETDWKILAIDVTD 3
>20119
          Length = 548

 Score = 29.3 bits (64), Expect = 1.7,   Method: Compositional matrix adjust.
 Identities = 9/17 (52%), Positives = 13/17 (76%)
 Frame = -2

Query: 119 PIDVCEIGSKVCARGEI 135
           P+ VC IG++VC RG +
Sbjct: 127 PLQVCHIGTQVCGRGGV 77
>14976
          Length = 560

 Score = 28.1 bits (61), Expect = 4.5,   Method: Compositional matrix adjust.
 Identities = 11/22 (50%), Positives = 14/22 (63%)
 Frame = -3

Query: 241 SCMNTTVSESPFKCDPDAAKAI 262
           SC+N   +ES F CDP   +AI
Sbjct: 156 SCVNLFYAESFFPCDPQTCQAI 91
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|10946870|ref|NP_067448.1| aldo-keto reductase family
1, member A4 (aldehyde reductase) [Mus musculus]
         (325 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

17411                                                                 230   5e-61
00500                                                                 189   1e-49
09575                                                                 168   3e-42
02477                                                                 129   1e-30
20851                                                                  91   2e-24
31792                                                                  90   2e-18
08973                                                                  68   5e-12
24743                                                                  58   4e-09
28188                                                                  55   5e-08
26455                                                                  51   6e-07
05102                                                                  37   0.007
13564                                                                  32   0.28 
11369                                                                  28   4.3  
>17411
          Length = 1104

 Score =  230 bits (587), Expect = 5e-61,   Method: Compositional matrix adjust.
 Identities = 125/322 (38%), Positives = 186/322 (57%), Gaps = 2/322 (0%)
 Frame = -3

Query: 2    TASSVLLHTGQKMPLIGLGTWKSEPGQVKAAIKHALSAGYRHIDCASVYGNETEIGEALK 61
            T+ +V L+ G ++P++GLGT+ S+  + + AIK A+  GYRHID A    NE E+G+A++
Sbjct: 1072 TSPTVKLNNGYEIPILGLGTYTSKDNEGEIAIKXAIDVGYRHIDTAYFXQNEFEVGKAIR 893

Query: 62   ESVGSGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWP--YAFE 119
            + +  G  V RE++F+ +KLWN  H P+ VE A RK LA L ++Y+DLYL+H P  Y F 
Sbjct: 892  DKIAEG-VVQREDIFLVTKLWNIHHDPKLVESACRKQLALLCMDYIDLYLIHQPVGYKFI 716

Query: 120  RGDNPFPKNADGTVRYDSTHYKETWKALEVLVAKGLVKALGLSNFNSRQIDDVLSVASVR 179
              +   PK+A+  ++     Y +T+KA+E LV  GLV+++G+SNFNS Q+  V++   ++
Sbjct: 715  DEETLVPKDANNELQLSDVDYLDTYKAMEQLVKIGLVRSIGVSNFNSEQLLRVINNCEIK 536

Query: 180  PAVLQVECHPYLAQNELIAHCHARGLEVTAYSPLGSSDRAWRHPDXXXXXXXXXXXXXXX 239
            P   QVEC P + Q +LIA C   G+ +TAY PLG        P+               
Sbjct: 535  PVTNQVECSPAINQKKLIAFCKQHGVTLTAYRPLGKPQPDQNKPE---YLYSPEVKAIAQ 365

Query: 240  KHGRSPAQILLRWQVQRKVICIPKSINPSRILQNIQVFDFTFSPEEMKQLDALNKNWRYI 299
            K+ +S  Q++LR+ V+   + IPKS NP RI +N  +FDF  + EE   LD  N   R  
Sbjct: 364  KYKKSAPQVILRYLVELGTLPIPKSSNPGRIAENFNIFDFELTAEEKCVLDGYNTGERN- 188

Query: 300  VPMITVDGKRVPRDAGHPLYPF 321
            VPM ++          H  YPF
Sbjct: 187  VPMTSL--------KHHKYYPF 146
>00500
          Length = 730

 Score =  189 bits (479), Expect(2) = 1e-49,   Method: Compositional matrix adjust.
 Identities = 93/216 (43%), Positives = 143/216 (66%), Gaps = 4/216 (1%)
 Frame = +2

Query: 10  TGQKMPLIGLGTW---KSEPGQVKAAIKHALSAGYRHIDCASVYGNETEIGEALKESVGS 66
           TGQ MP++  GTW   +S+ G+V   +K AL AGY H+D A VY NE E+G+A+ + +  
Sbjct: 2   TGQLMPVVAYGTWTVWQSKAGEVYRGVKTALEAGYGHVDTAWVYDNEHEVGQAVADVIQE 181

Query: 67  GKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAF-ERGDNPF 125
           G ++ R ++F+T+K+W+T H  E V+  + K+LA L+L Y+DL LMH+P +F +  D+ F
Sbjct: 182 G-SLTRGDIFITTKIWDTYHSRERVKLNVEKSLAKLKLSYVDLVLMHYPTSFKDTDDDNF 358

Query: 126 PKNADGTVRYDSTHYKETWKALEVLVAKGLVKALGLSNFNSRQIDDVLSVASVRPAVLQV 185
           PK  DG + Y +    +TWK LE  V  GLV+ +G+SNFNS+QI  V+  AS++P  LQV
Sbjct: 359 PKGPDGKIIYSNHDLLDTWKGLEDCVRAGLVRNIGVSNFNSQQIKRVVDAASIKPCNLQV 538

Query: 186 ECHPYLAQNELIAHCHARGLEVTAYSPLGSSDRAWR 221
           E +P ++   L+    ++GL V++Y+PLG+  R +R
Sbjct: 539 EINPTMSNERLVKFAESQGLTVSSYAPLGAPGRKYR 646

 Score = 25.4 bits (54), Expect(2) = 1e-49,   Method: Compositional matrix adjust.
 Identities = 8/13 (61%), Positives = 12/13 (92%)
 Frame = +3

Query: 240 KHGRSPAQILLRW 252
           K G++PAQ++LRW
Sbjct: 690 KKGKTPAQVILRW 728
>09575
          Length = 734

 Score =  168 bits (426), Expect = 3e-42,   Method: Compositional matrix adjust.
 Identities = 82/197 (41%), Positives = 118/197 (59%), Gaps = 1/197 (0%)
 Frame = +1

Query: 103 QLEYLDLYLMHWPYAF-ERGDNPFPKNADGTVRYDSTHYKETWKALEVLVAKGLVKALGL 161
           +L Y+DL LMH+P +F +  D+ FPK  DG + Y +    +TWK LE  V  GLV+ +G+
Sbjct: 1   KLSYVDLVLMHYPTSFKDTDDDNFPKGPDGKIIYSNHDLLDTWKGLEDCVXAGLVRNIGV 180

Query: 162 SNFNSRQIDDVLSVASVRPAVLQVECHPYLAQNELIAHCHARGLEVTAYSPLGSSDRAWR 221
           SNFNS+QI  V+  AS++P  LQVE +P ++   L+    ++GL V++Y+PLG+  R W+
Sbjct: 181 SNFNSQQIKRVVDAASIKPCNLQVEINPTMSNERLVKFAESQGLTVSSYAPLGAPGRPWK 360

Query: 222 HPDXXXXXXXXXXXXXXXKHGRSPAQILLRWQVQRKVICIPKSINPSRILQNIQVFDFTF 281
                             K G++PAQ++LRW +QR V    KS+N  RI QNI VF+F  
Sbjct: 361 ESTDPCAIEDPVVTGIASKKGKTPAQVILRWLLQRGVCVCVKSLNVDRIRQNIDVFNFEL 540

Query: 282 SPEEMKQLDALNKNWRY 298
           S +EM Q+  LNK   Y
Sbjct: 541 SEDEMTQMSGLNKTSVY 591
>02477
          Length = 1091

 Score =  129 bits (324), Expect = 1e-30,   Method: Compositional matrix adjust.
 Identities = 73/211 (34%), Positives = 114/211 (54%), Gaps = 6/211 (2%)
 Frame = +1

Query: 94  ALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPKNADGTVR---YDSTHYKE---TWKAL 147
           A  ++L+ LQ  YLDL+L+HWP               GT +   +D+ H      +W  +
Sbjct: 22  ACLQSLSRLQCSYLDLFLIHWP---------------GTQKLQPHDARHKANRLASWADM 156

Query: 148 EVLVAKGLVKALGLSNFNSRQIDDVLSVASVRPAVLQVECHPYLAQNELIAHCHARGLEV 207
           E L  +G +KA+G+SNF    ++++L+V SV+PAVLQ+E HP+L Q+ L++ C    +  
Sbjct: 157 EQLHKEGKLKAIGVSNFLQHHLEEILAVCSVKPAVLQIEFHPHLVQSNLLSWCTQNTIHF 336

Query: 208 TAYSPLGSSDRAWRHPDXXXXXXXXXXXXXXXKHGRSPAQILLRWQVQRKVICIPKSINP 267
            AYS LG++       D               ++ R+PAQILL W VQ+ V  +PKS N 
Sbjct: 337 QAYSSLGTT------SDNNKLLTDQTVQSIASRYNRTPAQILLHWAVQQGVGVLPKSTNQ 498

Query: 268 SRILQNIQVFDFTFSPEEMKQLDALNKNWRY 298
             I +N ++FDFT    +M+ L +L+ +  Y
Sbjct: 499 KHIEENGEIFDFTLEDSDMQALSSLHSDTHY 591
>20851
          Length = 408

 Score = 90.9 bits (224), Expect(2) = 2e-24,   Method: Compositional matrix adjust.
 Identities = 45/84 (53%), Positives = 57/84 (67%)
 Frame = +2

Query: 41  YRHIDCASVYGNETEIGEALKESVGSGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLA 100
           YRH D A VY  E  +GE +   +  G  V RE+LF+ SKLWNT H    VE +LR+TL 
Sbjct: 2   YRHFDTAWVYETEKAVGEGIARKIQDG-TVKREDLFIVSKLWNTCH--SRVEASLRETLN 172

Query: 101 DLQLEYLDLYLMHWPYAFERGDNP 124
           +LQL YLDLYL+HWP AF++ +NP
Sbjct: 173 NLQLGYLDLYLIHWPIAFKKVENP 244

 Score = 39.3 bits (90), Expect(2) = 2e-24,   Method: Compositional matrix adjust.
 Identities = 17/36 (47%), Positives = 27/36 (75%)
 Frame = +1

Query: 140 YKETWKALEVLVAKGLVKALGLSNFNSRQIDDVLSV 175
           + +T+K +E LV + LV +LG+SNFN+ Q+  +LSV
Sbjct: 292 FVDTYKDMEKLVDQRLVNSLGVSNFNTHQLTRLLSV 399
>31792
          Length = 377

 Score = 89.7 bits (221), Expect = 2e-18,   Method: Compositional matrix adjust.
 Identities = 50/122 (40%), Positives = 70/122 (57%), Gaps = 2/122 (1%)
 Frame = -3

Query: 145 KALEVLVAKGLVKALGLSNFNSRQIDDVLSVASVRPAVLQVECHPYLAQNELIAHCHARG 204
           K LE LV +G +++LG+SNFNS Q+D +  VA+V+P + QVECH YLAQ EL A C  R 
Sbjct: 372 KELEKLVQEGKIRSLGISNFNSVQVDLINFVATVKPVINQVECHAYLAQKELQAFCQKRN 193

Query: 205 LEVTAYSPLGSSDRAWRHPDXX--XXXXXXXXXXXXXKHGRSPAQILLRWQVQRKVICIP 262
           + + A++PLGS  R                       K+ ++PAQ+LLR   QR +  + 
Sbjct: 192 IFLQAFAPLGSPGRPEHMVTDGDPVLLEEPVLASIGEKYKKTPAQVLLRNLFQRGMAMVA 13

Query: 263 KS 264
           KS
Sbjct: 12  KS 7
>08973
          Length = 567

 Score = 68.2 bits (165), Expect = 5e-12,   Method: Compositional matrix adjust.
 Identities = 44/137 (32%), Positives = 62/137 (45%)
 Frame = -3

Query: 189 PYLAQNELIAHCHARGLEVTAYSPLGSSDRAWRHPDXXXXXXXXXXXXXXXKHGRSPAQI 248
           P   Q++L AH    G+ + AY PL     A   P                K+GR+ AQI
Sbjct: 565 PAFQQHKLRAHAKKHGIVICAYCPLARPQPARHWPPFLYDERAQQLAK---KYGRTAAQI 395

Query: 249 LLRWQVQRKVICIPKSINPSRILQNIQVFDFTFSPEEMKQLDALNKNWRYIVPMITVDGK 308
            L + +Q  V+ +PKS N  RI +N   FDF   PE+M  ++  + N R  VP   +   
Sbjct: 394 CLXYLIQSGVVPLPKSSNKKRIAENFNCFDFELMPEDMLAMEKYHTNVR-TVPFSGM--- 227

Query: 309 RVPRDAGHPLYPFNDPY 325
                + H  YPFND +
Sbjct: 226 -----SSHQYYPFNDEF 191
>24743
          Length = 342

 Score = 58.2 bits (139), Expect = 4e-09,   Method: Compositional matrix adjust.
 Identities = 34/99 (34%), Positives = 53/99 (53%), Gaps = 6/99 (6%)
 Frame = +3

Query: 90  DVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPKNADGTVR---YDSTHYKE---T 143
               A  ++L+ LQ  YLDL+L+HWP               GT +   +D+ H      +
Sbjct: 33  SCRAACLQSLSRLQCSYLDLFLIHWP---------------GTQKLQPHDARHKANRLXS 167

Query: 144 WKALEVLVAKGLVKALGLSNFNSRQIDDVLSVASVRPAV 182
           W  +E L  +G +KA+G+SNF    ++++L+V SVRPAV
Sbjct: 168 WADMEQLHKEGKLKAIGVSNFLQHHLEEILAVCSVRPAV 284
>28188
          Length = 1255

 Score = 54.7 bits (130), Expect = 5e-08,   Method: Compositional matrix adjust.
 Identities = 55/182 (30%), Positives = 82/182 (45%), Gaps = 15/182 (8%)
 Frame = +3

Query: 33  IKHALSAGYRHIDCASVYG---NETEIGEALKESVGSGKAVPREELFVTSKL-------- 81
           ++ AL AG  +ID A  YG   +E  +G+ALK        VPRE  ++ SK+        
Sbjct: 180 VQEALKAGINYIDTAPWYGQGRSEEVLGKALKN-------VPREAYYIASKVGRYALDYE 338

Query: 82  ----WNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPKNADGTVRYDS 137
               ++TK   E V+    K+L  L L Y+D+  +H        D  F +N D  +    
Sbjct: 339 NMFDFSTKKTHESVQ----KSLKLLGLSYVDVIQIH--------DIEFAENLDIIL---- 470

Query: 138 THYKETWKALEVLVAKGLVKALGLSNFNSRQIDDVLSVASVRPAVLQVECHPYLAQNELI 197
               ET  ALE LV +G  K +GLS +    + + +S A  R   +   C   LA N L+
Sbjct: 471 ---NETLPALEQLVMEGKAKYIGLSAYPISVLKECISRAEGRFHTVLTYCRYTLADNTLL 641

Query: 198 AH 199
            +
Sbjct: 642 EY 647
>26455
          Length = 466

 Score = 51.2 bits (121), Expect = 6e-07,   Method: Compositional matrix adjust.
 Identities = 30/82 (36%), Positives = 49/82 (59%)
 Frame = -3

Query: 3   ASSVLLHTGQKMPLIGLGTWKSEPGQVKAAIKHALSAGYRHIDCASVYGNETEIGEALKE 62
           A +V L+ G ++P++GLGT+ S+  + + AIKHA+  GYRHID A  Y  +T +  A   
Sbjct: 266 APTVKLNNGYEIPILGLGTYTSKDNEGEIAIKHAIDVGYRHIDTA--YFIKTNLRLARLF 93

Query: 63  SVGSGKAVPREELFVTSKLWNT 84
           ++   KA+    +F  S+ + T
Sbjct: 92  AIKLLKALSSVRIFS*SQNYGT 27

 Score = 43.1 bits (100), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 28/76 (36%), Positives = 43/76 (56%), Gaps = 2/76 (2%)
 Frame = -2

Query: 15  PLIGLGTWKSEPGQVKAAIKH--ALSAGYRHIDCASVYGNETEIGEALKESVGSGKAVPR 72
           P +G   +K + G+     +H   LSA Y H  C   Y NE E+G+A+++ +  G  V R
Sbjct: 225 PRLGHIYFKRQRGRNCYKTRH*RGLSA-Y*H--CV-FYQNEFEVGKAIRDKIAEG-VVQR 61

Query: 73  EELFVTSKLWNTKHHP 88
           E++F+ +KLWN  H P
Sbjct: 60  EDIFLVTKLWNIHHDP 13
>05102
          Length = 1532

 Score = 37.4 bits (85), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 29/119 (24%), Positives = 54/119 (45%), Gaps = 2/119 (1%)
 Frame = -3

Query: 97   KTLADLQLEYLDLYLMHWPYAFERGDNPFPKNADGTVRYDSTHYKETWKALEVLVAKGLV 156
            + L  ++ +Y+D+  +H+P         F K+            KET   L+  +A+G +
Sbjct: 1524 RALRKMETDYIDILQIHFP--------SFVKDM-----------KETLAELDSQIARGRL 1402

Query: 157  KALGLSNFNSRQIDDVLSVASVRPAVLQVECHPY--LAQNELIAHCHARGLEVTAYSPL 213
            +  G SNF  + +   L  A  +P V Q+  +      + ++ + C A  + + AYSPL
Sbjct: 1401 RHYGFSNFGPKNLKAFLD-AGAKPVVNQMGYNLLWRSVEYDVQSICAANNISILAYSPL 1228
>13564
          Length = 842

 Score = 32.3 bits (72), Expect = 0.28,   Method: Compositional matrix adjust.
 Identities = 26/118 (22%), Positives = 51/118 (43%)
 Frame = +1

Query: 94  ALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPKNADGTVRYDSTHYKETWKALEVLVAK 153
           A+ K + +LQ+ +++  L+                 D   +      K  WKALE LV +
Sbjct: 13  AVEKVMGELQVSFVETVLLSLSMY------------DSEDQIAVEELKPYWKALEDLVDQ 156

Query: 154 GLVKALGLSNFNSRQIDDVLSVASVRPAVLQVECHPYLAQNELIAHCHARGLEVTAYS 211
             V ++G+++ +  ++D +   A V+P + QV           +A C     ++T Y+
Sbjct: 157 ERVLSIGVADLDKHKLDQLYQWAKVKPRINQVN----------LASCCVMPKDLTEYA 300
>11369
          Length = 707

 Score = 28.5 bits (62), Expect = 4.3,   Method: Compositional matrix adjust.
 Identities = 22/94 (23%), Positives = 42/94 (44%), Gaps = 8/94 (8%)
 Frame = +3

Query: 27  GQVKAAIKHALSAGYRHIDCASVYGNETEIGEALKESVG-SGKAVPREELFVT------- 78
           G V   +  + +A  +HI        ET I  ++   +  S    P++ ++++       
Sbjct: 378 GGVMVLVNKSYAAYVKHI--------ETSIDNSIVLKIDKSLFGTPKDIMYISCYIPPYD 533

Query: 79  SKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLM 112
           SK W   HH   +EP ++  L DLQ  + D +++
Sbjct: 534 SKFWQGSHHGYGMEPIVQSVL-DLQNSHDDFHIL 632
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|162138894|ref|NP_079924.2| phenylalanyl-tRNA
synthetase, alpha subunit [Mus musculus]
         (508 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

28972                                                                  94   5e-61
26507                                                                 120   1e-27
29946                                                                  30   1.6  
20098                                                                  28   8.2  
>28972
          Length = 418

 Score = 94.4 bits (233), Expect(3) = 5e-61,   Method: Compositional matrix adjust.
 Identities = 44/60 (73%), Positives = 49/60 (81%)
 Frame = +3

Query: 357 FRNETLDATHLAEFHQIEGVIADHGLTLGHLMGVLREFFTKLGITQLRFKPAYNPYTEPS 416
           FRNE LDATHLAEFHQIEG++AD GLTLG LMGV+ EFF KLGI +LRFKPA  P   P+
Sbjct: 3   FRNENLDATHLAEFHQIEGLVADRGLTLGDLMGVIHEFFMKLGIKKLRFKPA*TPTLSPA 182

 Score = 91.7 bits (226), Expect(3) = 5e-61,   Method: Composition-based stats.
 Identities = 40/45 (88%), Positives = 44/45 (97%)
 Frame = +1

Query: 451 NVSVIAWGLSLERPTMIKYGINNIRELVGHKVNLQMVYDSPVCRL 495
           +VSVIAWGLSLERPTMIKYGINNIR+L+G KVNLQMVYD+PVCRL
Sbjct: 283 DVSVIAWGLSLERPTMIKYGINNIRDLIGPKVNLQMVYDNPVCRL 417

 Score = 88.2 bits (217), Expect(3) = 5e-61,   Method: Compositional matrix adjust.
 Identities = 39/50 (78%), Positives = 43/50 (86%)
 Frame = +2

Query: 410 NPYTEPSMEVFSYHQGLKKWVEVGNSGVFRPEMLLPMGLPENVSVIAWGL 459
           NPYTEPSMEVFSYH+GL+KWVEVGNSGVFRPEMLLPMG+PE    +  G 
Sbjct: 161 NPYTEPSMEVFSYHEGLQKWVEVGNSGVFRPEMLLPMGMPETYQSLPGGC 310
>26507
          Length = 420

 Score =  120 bits (301), Expect = 1e-27,   Method: Compositional matrix adjust.
 Identities = 62/138 (44%), Positives = 89/138 (64%), Gaps = 1/138 (0%)
 Frame = -2

Query: 32  VEHQAVVGAVKSLQALGEVIEAELRSTKCWELTTEGEEIAREGSHEARVFRSIPLEGLVQ 91
           V+HQ +VG  K    +G   E    + K  +LT EG  +   GSHEA +FR++P EG+ Q
Sbjct: 419 VDHQVLVGDCKKSSVIGRYCERGPGTDKFLQLTDEGSSVVANGSHEALLFRAVPSEGIPQ 240

Query: 92  SELMHL-PSGKVGFSKAMSNKWIRVDKSAADGPRVFRVVDSIEDEVQKRLQLVQAGQAEK 150
           +EL+ L P+ KVGFSKAMS  WIR+DKSA   PR+F  +D+IED VQ+ L  ++    + 
Sbjct: 239 TELLKLVPNAKVGFSKAMSAGWIRIDKSAGGIPRIFPKIDTIEDTVQECLIKIRDMSLDG 60

Query: 151 LAEKERNELRKRKLLTEV 168
           +++  +NE +KRKL+ EV
Sbjct: 59  ISDATKNEYKKRKLILEV 6
>29946
          Length = 1192

 Score = 30.4 bits (67), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 11/27 (40%), Positives = 18/27 (66%)
 Frame = +3

Query: 350 YFSIDRVFRNETLDATHLAEFHQIEGV 376
           +  +  V+R + +D+TH   FHQ+EGV
Sbjct: 615 FLVVGDVYRRDEIDSTHYPVFHQMEGV 695
>20098
          Length = 1020

 Score = 28.1 bits (61), Expect = 8.2,   Method: Compositional matrix adjust.
 Identities = 16/59 (27%), Positives = 28/59 (47%), Gaps = 2/59 (3%)
 Frame = -2

Query: 146 GQAEKLAEKERNELRKRKLLTEVILKTYWVSKGKAFSTSVSKQEAELSPEMISS--GSW 202
           G+   L+   R  +R   + ++   KT++  K  AF T+V K    + PE+     G+W
Sbjct: 833 GRQSVLSTSSRTSMRPGVIKSDFAAKTFFSYKDTAFQTAVDKVSTIIKPELDGELLGAW 657
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|86476059|ref|NP_001034477.1| WD repeat domain 37
isoform a [Mus musculus]
         (496 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

37180                                                                 151   7e-61
27806                                                                 134   1e-31
30256                                                                  72   4e-13
02960                                                                  70   1e-12
01327                                                                  67   2e-11
13335                                                                  60   2e-09
00561                                                                  60   3e-09
12806                                                                  59   3e-09
03156                                                                  57   2e-08
17598                                                                  54   2e-07
27465                                                                  53   2e-07
18981                                                                  52   4e-07
02147                                                                  51   1e-06
12960                                                                  50   2e-06
17602                                                                  48   1e-05
26107                                                                  47   1e-05
01805                                                                  47   1e-05
03387                                                                  47   2e-05
19949                                                                  47   3e-05
01598                                                                  44   2e-04
13278                                                                  44   2e-04
10264                                                                  44   2e-04
30295                                                                  43   2e-04
03395                                                                  43   3e-04
19863                                                                  42   4e-04
12574                                                                  40   0.002
01462                                                                  40   0.002
19498                                                                  39   0.004
17298                                                                  39   0.005
21105                                                                  38   0.012
26939                                                                  38   0.012
17266                                                                  37   0.015
11915                                                                  37   0.019
15972                                                                  37   0.027
04524                                                                  36   0.032
07781                                                                  36   0.038
19140                                                                  35   0.055
31384                                                                  35   0.079
20662                                                                  35   0.098
04088                                                                  34   0.12 
15118                                                                  34   0.12 
15780                                                                  34   0.12 
01768                                                                  34   0.15 
27270                                                                  33   0.22 
16199                                                                  33   0.25 
14555                                                                  32   0.40 
31474                                                                  32   0.46 
05393                                                                  32   0.69 
21921                                                                  32   0.75 
04358                                                                  31   0.88 
16105                                                                  31   1.3  
13890                                                                  30   2.0  
25400                                                                  30   2.0  
14500                                                                  30   2.5  
21960                                                                  30   2.6  
02090                                                                  30   3.0  
06576                                                                  28   8.7  
>37180
          Length = 681

 Score =  151 bits (381), Expect(2) = 7e-61,   Method: Compositional matrix adjust.
 Identities = 73/96 (76%), Positives = 81/96 (84%)
 Frame = +1

Query: 321 LTGHDQELTHCCTHPTQRLVVTSSRDTTFRLWDFRDPSIHSVNVFQGHTDTVTSAVFTVG 380
           L GHDQEL+    HPTQRLVVTSS+D TFRLWDFRD ++  VNVFQGHT  VTSAVF  G
Sbjct: 7   LNGHDQELSDVHAHPTQRLVVTSSKDMTFRLWDFRDSAL-LVNVFQGHTQPVTSAVFASG 183

Query: 381 DNVVSGSDDRTVKVWDLKNMRSPIATIRTDSAINRI 416
           D VVSGSDDRTV+VWD++NMRSPIATIRTDSA+NR 
Sbjct: 184 DKVVSGSDDRTVRVWDMRNMRSPIATIRTDSAVNRF 291

 Score =  101 bits (252), Expect(2) = 7e-61,   Method: Compositional matrix adjust.
 Identities = 40/65 (61%), Positives = 56/65 (86%)
 Frame = +3

Query: 425 IALPHDNRQVRLFDMSGVRLARLPRSSRQGHRRMVCCSAWSEDHPICNLFTCGFDRQAIG 484
           IA+PHDNR VRL+D++GVR+ RLPRS+RQGH RMVC  +W+++   CNLF+CGFDRQ +G
Sbjct: 324 IAIPHDNRHVRLYDINGVRIGRLPRSNRQGHTRMVCAVSWADESAPCNLFSCGFDRQVLG 503

Query: 485 WNINI 489
           W++++
Sbjct: 504 WHVSL 518

 Score = 28.9 bits (63), Expect = 5.3,   Method: Compositional matrix adjust.
 Identities = 10/32 (31%), Positives = 20/32 (62%)
 Frame = +1

Query: 197 GHVGSVNSIKFHPSEQLALTASGDQTAHIWRY 228
           GH   ++ +  HP+++L +T+S D T  +W +
Sbjct: 13  GHDQELSDVHAHPTQRLVVTSSKDMTFRLWDF 108
>27806
          Length = 419

 Score =  134 bits (336), Expect = 1e-31,   Method: Compositional matrix adjust.
 Identities = 68/142 (47%), Positives = 98/142 (69%), Gaps = 5/142 (3%)
 Frame = -1

Query: 159 IWDVSVTRTQPIVLGTASADHTALLWSIETGKCLVKYAGHVGSVNSIKFHPSEQLALTAS 218
           +W+VSV+R    ++GTASADHTA ++SIETG C++ Y GH GSVN+++FHP + L LTAS
Sbjct: 419 VWEVSVSRPGHPIIGTASADHTARIYSIETGACVLTYGGHQGSVNAVRFHPGQDLVLTAS 240

Query: 219 GDQTAHIWRYVVQLPTPQPVADTSQQI-SGEDEIECSDKDEPDIDGD----VSSDCPTVR 273
           GD TAH+WR   Q   P  ++D  + + SGED+++ S+K+E   DG+    +S+   T +
Sbjct: 239 GDHTAHVWR--AQFSQPSLMSDLYKSMSSGEDDVDASEKEE-GTDGESTDTLSTTPATQQ 69

Query: 274 VPLTSLKSHQGVVIAADWLVGG 295
            PL  L SH  V++AADW+ GG
Sbjct: 68  TPLLELTSHADVLVAADWVAGG 3

 Score = 45.1 bits (105), Expect = 8e-05,   Method: Compositional matrix adjust.
 Identities = 26/66 (39%), Positives = 35/66 (53%), Gaps = 2/66 (3%)
 Frame = -1

Query: 298 VVTASWDRTANLYDVETSELVHSLTGHDQELTHCCTHPTQRLVVTSSRDTTFRLW--DFR 355
           + TAS D TA +Y +ET   V +  GH   +     HP Q LV+T+S D T  +W   F 
Sbjct: 380 IGTASADHTARIYSIETGACVLTYGGHQGSVNAVRFHPGQDLVLTASGDHTAHVWRAQFS 201

Query: 356 DPSIHS 361
            PS+ S
Sbjct: 200 QPSLMS 183
>30256
          Length = 961

 Score = 72.4 bits (176), Expect = 4e-13,   Method: Compositional matrix adjust.
 Identities = 74/297 (24%), Positives = 127/297 (42%), Gaps = 3/297 (1%)
 Frame = +3

Query: 147 QLVKEYIGHRDGIWDVSVTRTQPIVLGTASADHTALLWSIETGKCLVKYAGHVGSVNSIK 206
           + +K  IGH  G+W   +T    I   + S D +  +W+ +TG C     GH  +V  + 
Sbjct: 15  RCIKNLIGHTGGVWSSQMTGNTVI---SGSTDRSLKVWNADTGVCTHTLYGHSSTVRCLS 185

Query: 207 FHPSEQLALTASGDQTAHIWRYVVQLPTPQPVADTSQQISGEDEIECSDKDEPDIDGDVS 266
              S +  ++ S D T  +W                       +IE             S
Sbjct: 186 L--SGKKVVSGSRDATLRVW-----------------------DIE-------------S 251

Query: 267 SDCPTVRVPLTSLKSHQGVVIAADWLVGGKQVVTASWDRTANLYDVETSELVHSLTGHDQ 326
             C      L  L  H   V    +   GK+VV+ + D T  ++D +T+  +H+L GH  
Sbjct: 252 GHC------LNVLLGHMAAVRCVQY--DGKRVVSGAXDYTVRVWDPDTASCLHTLQGHTN 407

Query: 327 ELTHCCTHPTQRLVVTSSRDTTFRLWDFRDPSIHSVNVFQGHTDTVTSAVFTVGDNVVSG 386
            +           VV+ S DT+ R+WD R   +  V+   GH  ++TS +    + +VSG
Sbjct: 408 RVYS--LQFDGVYVVSGSLDTSIRVWDVRCGKL--VHTLMGH-QSLTSGLELKDNLLVSG 572

Query: 387 SDDRTVKVWDL---KNMRSPIATIRTDSAINRINVCVGQKIIALPHDNRQVRLFDMS 440
           + D TVKVWD+   K +++ +   +  SA+  +     +K +    D+  V+L+D++
Sbjct: 573 NADSTVKVWDVHTGKCLQTLLGPNKHRSAVTCLQ--FNKKFVVTCSDDGTVKLWDLN 737
>02960
          Length = 1577

 Score = 70.5 bits (171), Expect = 1e-12,   Method: Compositional matrix adjust.
 Identities = 77/283 (27%), Positives = 121/283 (42%), Gaps = 11/283 (3%)
 Frame = +2

Query: 174 TASADHTALLWSI--ETGK--CLVKYAGHVGSVNSIKFHPSEQLALTASGDQTAHIWRYV 229
           T S D TAL+W    ET +  C +   GH  SV+ +   P  Q   T S D+   +W   
Sbjct: 668 TGSHDQTALVWQWQRETNEVDCRLSCRGHAASVDCVAVSPDSQQMCTGSWDKMLKLW--- 838

Query: 230 VQLPTPQPVADTSQQISGEDEIECSDKDEPDIDGDVSSDCPTVRVPLTSLKSHQGVVIAA 289
                      T   + G+   +  D + P      +      RVP+ +L  H   V A 
Sbjct: 839 ----------STDCNVDGD---QSEDTERPSKKKKSAKSTTQTRVPVLTLSGHAEAVSAV 979

Query: 290 DWLVGGKQVVTASWDRTANLYDVETSELVHSLTGHDQELTHCCTHPTQRLVVTSSRDTTF 349
            WL    +VVT+SWD +  L+D+ T++   SL    + +      P   +++T S D   
Sbjct: 980 RWL-DPHRVVTSSWDHSLRLWDLHTAQQT-SLIQGSKAVLDVAYSPLSHMLITGSADRHV 1153

Query: 350 RLWDFRDPSIHSVN-VFQGHTDTVTSAVF--TVGDNVVSGSDDRTVKVWDLKNMRSPIAT 406
           RL D R     +V   F  HT  VT   +  T     +SGS D  +K+WD    RSP AT
Sbjct: 1154RLVDPRCSEGETVKCAFTSHTGWVTGVDWSPTREHLFLSGSYDNVLKLWD---TRSPKAT 1324

Query: 407 IRT----DSAINRINVCVGQKIIALPHDNRQVRLFDMSGVRLA 445
           +      +  I  ++  + + +++   DN+ + +F  S  +L 
Sbjct: 1325LYDMNWHEDRILAVDWSIPELLLSGGVDNK-LHVFSYSSAKLG 1450
>01327
          Length = 2215

 Score = 66.6 bits (161), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 42/150 (28%), Positives = 77/150 (51%), Gaps = 2/150 (1%)
 Frame = +3

Query: 299 VTASWDRTANLYDVETSELVHSLTGHDQELTHCCTHPTQRLVVTSSRDTTFRLWDFRDPS 358
           ++ S D++  LYD +   L    TGHD+E+T  C   +   + ++SRD T ++W  +  +
Sbjct: 87  LSGSKDKSVVLYDYQNGRLEDRWTGHDREITKVCYGASCNGMFSASRDKTIKMW--QRGN 260

Query: 359 IHSVNVFQGHTDTVTSAVFTVGDN--VVSGSDDRTVKVWDLKNMRSPIATIRTDSAINRI 416
            HS+  F GH D V +A+    DN  + SGS D TV++WD++            + +  +
Sbjct: 261 SHSIRDFIGH-DMVVTAIHLNTDNTLLCSGSRDNTVRIWDVETGACLRQNNIPQNLVTDV 437

Query: 417 NVCVGQKIIALPHDNRQVRLFDMSGVRLAR 446
               G  +I    ++++VR++D   + + R
Sbjct: 438 KWLPGSHLIIQAGEDKEVRIYDSRTLGIVR 527

 Score = 53.9 bits (128), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 50/246 (20%), Positives = 101/246 (41%), Gaps = 16/246 (6%)
 Frame = +3

Query: 168 QPIVLGTASADHTALLWSIETGKCLVKYAGHVGSVNSIKFHPSEQLALTASGDQTAHIWR 227
           QP +  + S D + +L+  + G+   ++ GH   +  + +  S     +AS D+T  +W+
Sbjct: 72  QPGLCLSGSKDKSVVLYDYQNGRLEDRWTGHDREITKVCYGASCNGMFSASRDKTIKMWQ 251

Query: 228 ----YVVQLPTPQPVADTSQQISGEDEIECSDKDEPDI---DGDVSSDCPTVRVPLTSLK 280
               + ++      +  T+  ++ ++ + CS   +  +   D +  +      +P     
Sbjct: 252 RGNSHSIRDFIGHDMVVTAIHLNTDNTLLCSGSRDNTVRIWDVETGACLRQNNIP----- 416

Query: 281 SHQGVVIAADWLVGGKQVVTASWDRTANLYDVETSELVHSLTGHDQELTHCCTHPTQRLV 340
             Q +V    WL G   ++ A  D+   +YD  T  +V S T        C      +  
Sbjct: 417 --QNLVTDVKWLPGSHLIIQAGEDKEVRIYDSRTLGIVRSFTKKQYIQMSCDVTADGQFC 590

Query: 341 VTSS-----RDTTFRLWDFRDPSIHSVNVFQGHTDTVTSAVFTVGDN----VVSGSDDRT 391
           +T S           LW   D SI   N F+GH + + + +F   +     + + S D +
Sbjct: 591 LTCSNGFGGNGCEATLWQLSDGSIQ--NEFKGHREAIEACLFLPSNQDMTLIATASRDCS 764

Query: 392 VKVWDL 397
           V+VW++
Sbjct: 765 VRVWNM 782

 Score = 48.5 bits (114), Expect = 7e-06,   Method: Compositional matrix adjust.
 Identities = 63/296 (21%), Positives = 112/296 (37%), Gaps = 16/296 (5%)
 Frame = +3

Query: 123 KTTYKASTSKIVSSFKTTT----SRAICQLVKEYIGHRDGIWDVSVT----RTQPIVLGT 174
           K  Y AS + + S+ +  T     R     ++++IGH     D+ VT     T   +L +
Sbjct: 180 KVCYGASCNGMFSASRDKTIKMWQRGNSHSIRDFIGH-----DMVVTAIHLNTDNTLLCS 344

Query: 175 ASADHTALLWSIETGKCLVKYAGHVGSVNSIKFHPSEQLALTASGDQTAHIWRYVVQLPT 234
            S D+T  +W +ETG CL +       V  +K+ P   L + A  D+   I+        
Sbjct: 345 GSRDNTVRIWDVETGACLRQNNIPQNLVTDVKWLPGSHLIIQAGEDKEVRIY-------- 500

Query: 235 PQPVADTSQQISGEDEIECSDKDEPDIDGDVSSDCPTVRVPLTSLKSHQGVVIAADWLVG 294
                                            D  T+ + + S    Q + ++ D    
Sbjct: 501 ---------------------------------DSRTLGI-VRSFTKKQYIQMSCDVTAD 578

Query: 295 GKQVVTASWDRTAN-----LYDVETSELVHSLTGHDQELTHCCTHPTQR---LVVTSSRD 346
           G+  +T S     N     L+ +    + +   GH + +  C   P+ +   L+ T+SRD
Sbjct: 579 GQFCLTCSNGFGGNGCEATLWQLSDGSIQNEFKGHREAIEACLFLPSNQDMTLIATASRD 758

Query: 347 TTFRLWDFRDPSIHSVNVFQGHTDTVTSAVFTVGDNVVSGSDDRTVKVWDLKNMRS 402
            + R+W+           F+G T  +TS +     +V+ G+ +  V+V  L    S
Sbjct: 759 CSVRVWNMFTKECVCEQNFEG-TGPLTSMIAYGDGSVLVGTFNLGVQVMSLNGQSS 923
>13335
          Length = 863

 Score = 60.5 bits (145), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 60/241 (24%), Positives = 98/241 (40%), Gaps = 5/241 (2%)
 Frame = +1

Query: 172 LGTASADHTALLWSIETGKCLVKYAGHVGSVNSIKFHPSEQLALTASGDQTAHIWRYVVQ 231
           L + S D T  +W + T K +  Y GH  SV ++ + P+    ++ S +   ++W     
Sbjct: 106 LVSGSDDDTICMWEVATQKLVRSYVGHEDSVMALAYSPNGHYLVSGSPNGDLYVW----- 270

Query: 232 LPTPQPVADTSQQISGEDEIECSDKDEPDIDGDVSSDCPTVRVPLTSLKSHQGVVIAADW 291
                   D S    G         D  D+        PT         S   +++A   
Sbjct: 271 --------DASF---GHCRHLTLRVDAHDLGVTCCEFSPTFGTACAENSSTCNLLLA--- 408

Query: 292 LVGGKQVVTASWDRTANLYDVE-TSELVHSLTGHDQELTHCCTHPTQRLVVTSSRDTTFR 350
             GGK  +   W  +A +   E T +    L+GH   +  C   P+  L+ + S D + R
Sbjct: 409 -TGGKDNLIKLWTFSAQVGSPEVTLQCRDILSGHSDLVMACAFSPSSALLASGSFDKSVR 585

Query: 351 LWDFRDPSIHSVNVFQ---GHTDTVTSAVFTV-GDNVVSGSDDRTVKVWDLKNMRSPIAT 406
           LWD    S+  V +F     H+  VT   F++ G  + SGS DR +K+W L +  S +  
Sbjct: 586 LWD----SVKGVALFSIEACHSRFVTCCAFSIDGTLLASGSMDRIIKIWKLTDTSSIMGK 753

Query: 407 I 407
           +
Sbjct: 754 L 756

 Score = 37.4 bits (85), Expect = 0.013,   Method: Compositional matrix adjust.
 Identities = 44/229 (19%), Positives = 81/229 (35%), Gaps = 17/229 (7%)
 Frame = +1

Query: 147 QLVKEYIGHRDGIWDVSVT-RTQPIVLGTASADHTALLWSIETGKC---LVKYAGHVGSV 202
           +LV+ Y+GH D +  ++ +     +V G+ + D    +W    G C    ++   H   V
Sbjct: 160 KLVRSYVGHEDSVMALAYSPNGHYLVSGSPNGD--LYVWDASFGHCRHLTLRVDAHDLGV 333

Query: 203 NSIKFHPSEQLA----------LTASG--DQTAHIWRYVVQLPTPQPVADTSQQISGEDE 250
              +F P+   A          L A+G  D    +W +  Q+ +P            E  
Sbjct: 334 TCCEFSPTFGTACAENSSTCNLLLATGGKDNLIKLWTFSAQVGSP------------EVT 477

Query: 251 IECSDKDEPDIDGDVSSDCPTVRVPLTSLKSHQGVVIAADWLVGGKQVVTASWDRTANLY 310
           ++C D                       L  H  +V+A  +      + + S+D++  L+
Sbjct: 478 LQCRDI----------------------LSGHSDLVMACAFSPSSALLASGSFDKSVRLW 591

Query: 311 DVETSELVHSLTGHDQELTHCCTHPTQ-RLVVTSSRDTTFRLWDFRDPS 358
           D      + S+         CC       L+ + S D   ++W   D S
Sbjct: 592 DSVKGVALFSIEACHSRFVTCCAFSIDGTLLASGSMDRIIKIWKLTDTS 738

 Score = 37.4 bits (85), Expect = 0.014,   Method: Compositional matrix adjust.
 Identities = 44/194 (22%), Positives = 78/194 (40%), Gaps = 23/194 (11%)
 Frame = +1

Query: 297 QVVTASWDRTANLYDVETSELVHSLTGHDQELTHCCTHPTQRLVVTSSRDTTFRLWDFRD 356
            +V+ S D T  +++V T +LV S  GH+  +      P    +V+ S +    +WD   
Sbjct: 103 HLVSGSDDDTICMWEVATQKLVRSYVGHEDSVMALAYSPNGHYLVSGSPNGDLYVWDASF 282

Query: 357 PSIHSVNV-FQGHTDTVTSAVFT------VGDN-------VVSGSDDRTVKVWDLK-NMR 401
                + +    H   VT   F+        +N       + +G  D  +K+W     + 
Sbjct: 283 GHCRHLTLRVDAHDLGVTCCEFSPTFGTACAENSSTCNLLLATGGKDNLIKLWTFSAQVG 462

Query: 402 SPIATIRTDSAI----NRINVCV---GQKIIALPHDNRQVRLFD-MSGVRLARLPRSSRQ 453
           SP  T++    +    + +  C       ++A    ++ VRL+D + GV L  +      
Sbjct: 463 SPEVTLQCRDILSGHSDLVMACAFSPSSALLASGSFDKSVRLWDSVKGVALFSI----EA 630

Query: 454 GHRRMVCCSAWSED 467
            H R V C A+S D
Sbjct: 631 CHSRFVTCCAFSID 672
>00561
          Length = 1003

 Score = 59.7 bits (143), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 37/120 (30%), Positives = 61/120 (50%), Gaps = 3/120 (2%)
 Frame = -3

Query: 285 VVIAADWLVGGKQVVTASWDRTANLYDVETSELVHSLTGHDQELTHCCTHPTQRLVVTSS 344
           VV+++D    G   ++ SWD+T  L+D+   +      GH +++         R +V+ S
Sbjct: 848 VVLSSD----GNYALSGSWDQTLRLWDLAAGKTTRRFEGHTKDVLSVAFSADNRQIVSGS 681

Query: 345 RDTTFRLWDFRDPSIHSVNVFQGHTDTVTSAVFTVGDN---VVSGSDDRTVKVWDLKNMR 401
           RD T +LW+       ++    GHTD V+   F+   +   +VS   DRTVKVW+L N +
Sbjct: 680 RDKTIKLWNTLAECKFTIQE-DGHTDWVSCVRFSPNHSNPIIVSCGWDRTVKVWNLANCK 504

 Score = 58.2 bits (139), Expect = 8e-09,   Method: Compositional matrix adjust.
 Identities = 55/249 (22%), Positives = 95/249 (38%), Gaps = 1/249 (0%)
 Frame = -3

Query: 150 KEYIGHRDGIWDVSVTRTQPIVLGTASADHTALLWSIETGKCLVKYAGHVGSVNSIKFHP 209
           K   GH   I DV ++      L + S D T  LW +  GK   ++ GH   V S+ F  
Sbjct: 884 KRLYGHSHFISDVVLSSDGNYAL-SGSWDQTLRLWDLAAGKTTRRFEGHTKDVLSVAFSA 708

Query: 210 SEQLALTASGDQTAHIWRYVVQLPTPQPVADTSQQISGEDEIECSDKDEPDIDGDVSSDC 269
             +  ++ S D+T  +W  + +         T Q+    D + C                
Sbjct: 707 DNRQIVSGSRDKTIKLWNTLAE------CKFTIQEDGHTDWVSC---------------- 594

Query: 270 PTVRVPLTSLKSHQGVVIAADWLVGGKQVVTASWDRTANLYDVETSELVHSLTGHDQELT 329
             VR       +H   +I           V+  WDRT  ++++   +L ++  GH+  L 
Sbjct: 593 --VRFS----PNHSNPII-----------VSCGWDRTVKVWNLANCKLKNNHHGHNGYLN 465

Query: 330 HCCTHPTQRLVVTSSRDTTFRLWDFRDPSIHSVNVFQ-GHTDTVTSAVFTVGDNVVSGSD 388
                P   L  +  +D+   LWD  D      N++   H D + +  F+     +  + 
Sbjct: 464 TVTVSPDGSLCTSGGKDSKALLWDLND----GKNLYTLEHNDIINALCFSPNRYWLCVAY 297

Query: 389 DRTVKVWDL 397
             ++K+WDL
Sbjct: 296 GPSIKIWDL 270

 Score = 43.5 bits (101), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 45/197 (22%), Positives = 75/197 (38%), Gaps = 7/197 (3%)
 Frame = -3

Query: 298 VVTASWDRTANLYDVETSELVHS------LTGHDQELTHCCTHPTQRLVVTSSRDTTFRL 351
           +++AS D+T  ++ +   E  +       L GH   ++           ++ S D T RL
Sbjct: 965 IISASRDKTLIVWKLTRDEDTNYGYPQKRLYGHSHFISDVVLSSDGNYALSGSWDQTLRL 786

Query: 352 WDFRDPSIHSVNVFQGHTDTVTSAVFTVGD-NVVSGSDDRTVKVWDLKNMRSPIATIRTD 410
           WD    +  +   F+GHT  V S  F+  +  +VSGS D+T+K+W+   +     TI+ D
Sbjct: 785 WDLA--AGKTTRRFEGHTKDVLSVAFSADNRQIVSGSRDKTIKLWN--TLAECKFTIQED 618

Query: 411 SAINRINVCVGQKIIALPHDNRQVRLFDMSGVRLARLPRSSRQGHRRMVCCSAWSEDHPI 470
                                                      GH   V C  +S +H  
Sbjct: 617 -------------------------------------------GHTDWVSCVRFSPNHSN 567

Query: 471 CNLFTCGFDRQAIGWNI 487
             + +CG+DR    WN+
Sbjct: 566 PIIVSCGWDRTVKVWNL 516
>12806
          Length = 961

 Score = 59.3 bits (142), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 40/145 (27%), Positives = 64/145 (44%), Gaps = 3/145 (2%)
 Frame = +3

Query: 259 PDIDGDVSSDCPTVRVPLTSLKSHQGVVIAADWLVGGKQVVTASWDRTANLYDVETSELV 318
           P  DGD   +  T  VP  +L  H   +         +  +++SWD T  L+D++     
Sbjct: 102 PKKDGD---EDQTWGVPRKTLTGHSHFISDLALSADSRFALSSSWDATLRLWDIKKGSTT 272

Query: 319 HSLTGHDQELTHCCTHPTQRLVVTSSRDTTFRLWDFRDPSIHSVNVFQGHTDTVTSAVF- 377
                H +++      P  R + +  RD   ++W+      ++V+    HTD VT   F 
Sbjct: 273 SRFINHTRDVLTVAFSPDNRQIASGGRDKNLKIWNIMGECKYTVDA-NAHTDWVTCVRFH 449

Query: 378 --TVGDNVVSGSDDRTVKVWDLKNM 400
             T    VVS S+D+T+KVWD   M
Sbjct: 450 QDTKNPIVVSASNDKTIKVWDNHTM 524

 Score = 39.3 bits (90), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 46/210 (21%), Positives = 81/210 (38%)
 Frame = +3

Query: 150 KEYIGHRDGIWDVSVTRTQPIVLGTASADHTALLWSIETGKCLVKYAGHVGSVNSIKFHP 209
           K   GH   I D++++      L ++S D T  LW I+ G    ++  H   V ++ F P
Sbjct: 147 KTLTGHSHFISDLALSADSRFAL-SSSWDATLRLWDIKKGSTTSRFINHTRDVLTVAFSP 323

Query: 210 SEQLALTASGDQTAHIWRYVVQLPTPQPVADTSQQISGEDEIECSDKDEPDIDGDVSSDC 269
             +   +   D+   IW                  I GE    C    +  +D +  +D 
Sbjct: 324 DNRQIASGGRDKNLKIW-----------------NIMGE----C----KYTVDANAHTDW 428

Query: 270 PTVRVPLTSLKSHQGVVIAADWLVGGKQVVTASWDRTANLYDVETSELVHSLTGHDQELT 329
                 +T ++ HQ              VV+AS D+T  ++D  T  L ++  GH  ++T
Sbjct: 429 ------VTCVRFHQDT--------KNPIVVSASNDKTIKVWDNHTMTLKNTFVGHKAQIT 566

Query: 330 HCCTHPTQRLVVTSSRDTTFRLWDFRDPSI 359
                 +   +V+ S+D     W+  + S 
Sbjct: 567 --ALDMSTNYLVSGSKDGIAMTWNVAEGSF 650
>03156
          Length = 1014

 Score = 56.6 bits (135), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 36/127 (28%), Positives = 66/127 (51%), Gaps = 2/127 (1%)
 Frame = +1

Query: 322 TGHDQELTHCCTHPTQRLVVTSSRDTTFRLWDFRDPSIHSVNVFQGHTDTVTSAVFTVGD 381
           TGHD+E+T  C   +   + ++SRD T ++W  +  + HS+  F GH D V +A+    D
Sbjct: 46  TGHDREITKVCYGASCNGMFSASRDKTIKMW--QRGNSHSIRDFIGH-DMVVTAIHLNTD 216

Query: 382 N--VVSGSDDRTVKVWDLKNMRSPIATIRTDSAINRINVCVGQKIIALPHDNRQVRLFDM 439
           N  + SGS D TV++WD++            + +  +    G  +I    ++++VR++D 
Sbjct: 217 NTLLCSGSRDNTVRIWDVETGACLRQNNIPQNLVTDVKWLPGSHLIIQAGEDKEVRIYDS 396

Query: 440 SGVRLAR 446
             + + R
Sbjct: 397 RTLGIVR 417

 Score = 48.5 bits (114), Expect = 6e-06,   Method: Compositional matrix adjust.
 Identities = 63/296 (21%), Positives = 112/296 (37%), Gaps = 16/296 (5%)
 Frame = +1

Query: 123 KTTYKASTSKIVSSFKTTT----SRAICQLVKEYIGHRDGIWDVSVT----RTQPIVLGT 174
           K  Y AS + + S+ +  T     R     ++++IGH     D+ VT     T   +L +
Sbjct: 70  KVCYGASCNGMFSASRDKTIKMWQRGNSHSIRDFIGH-----DMVVTAIHLNTDNTLLCS 234

Query: 175 ASADHTALLWSIETGKCLVKYAGHVGSVNSIKFHPSEQLALTASGDQTAHIWRYVVQLPT 234
            S D+T  +W +ETG CL +       V  +K+ P   L + A  D+   I+        
Sbjct: 235 GSRDNTVRIWDVETGACLRQNNIPQNLVTDVKWLPGSHLIIQAGEDKEVRIY-------- 390

Query: 235 PQPVADTSQQISGEDEIECSDKDEPDIDGDVSSDCPTVRVPLTSLKSHQGVVIAADWLVG 294
                                            D  T+ + + S    Q + ++ D    
Sbjct: 391 ---------------------------------DSRTLGI-VRSFTKKQYIQMSCDVTAD 468

Query: 295 GKQVVTASWDRTAN-----LYDVETSELVHSLTGHDQELTHCCTHPTQR---LVVTSSRD 346
           G+  +T S     N     L+ +    + +   GH + +  C   P+ +   L+ T+SRD
Sbjct: 469 GQFCLTCSNGFGGNGCEATLWQLSDGSIQNEFKGHREAIEACLFLPSNQDMTLIATASRD 648

Query: 347 TTFRLWDFRDPSIHSVNVFQGHTDTVTSAVFTVGDNVVSGSDDRTVKVWDLKNMRS 402
            + R+W+           F+G T  +TS +     +V+ G+ +  V+V  L    S
Sbjct: 649 CSVRVWNMFTKECVCEQNFEG-TGPLTSMIAYGDGSVLVGTFNLGVQVMSLNGQSS 813

 Score = 45.1 bits (105), Expect = 6e-05,   Method: Compositional matrix adjust.
 Identities = 44/220 (20%), Positives = 88/220 (40%), Gaps = 16/220 (7%)
 Frame = +1

Query: 194 KYAGHVGSVNSIKFHPSEQLALTASGDQTAHIWR----YVVQLPTPQPVADTSQQISGED 249
           ++ GH   +  + +  S     +AS D+T  +W+    + ++      +  T+  ++ ++
Sbjct: 40  RWTGHDREITKVCYGASCNGMFSASRDKTIKMWQRGNSHSIRDFIGHDMVVTAIHLNTDN 219

Query: 250 EIECSDKDEPDI---DGDVSSDCPTVRVPLTSLKSHQGVVIAADWLVGGKQVVTASWDRT 306
            + CS   +  +   D +  +      +P       Q +V    WL G   ++ A  D+ 
Sbjct: 220 TLLCSGSRDNTVRIWDVETGACLRQNNIP-------QNLVTDVKWLPGSHLIIQAGEDKE 378

Query: 307 ANLYDVETSELVHSLTGHDQELTHCCTHPTQRLVVTSS-----RDTTFRLWDFRDPSIHS 361
             +YD  T  +V S T        C      +  +T S           LW   D SI  
Sbjct: 379 VRIYDSRTLGIVRSFTKKQYIQMSCDVTADGQFCLTCSNGFGGNGCEATLWQLSDGSIQ- 555

Query: 362 VNVFQGHTDTVTSAVFTVGDN----VVSGSDDRTVKVWDL 397
            N F+GH + + + +F   +     + + S D +V+VW++
Sbjct: 556 -NEFKGHREAIEACLFLPSNQDMTLIATASRDCSVRVWNM 672
>17598
          Length = 875

 Score = 53.9 bits (128), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 43/171 (25%), Positives = 71/171 (41%), Gaps = 3/171 (1%)
 Frame = +1

Query: 259 PDIDGDVSSDCPTVRVPLTSLKSHQGVVIAADWLVGGKQVVTASWDRTANLYDVETSELV 318
           P  DGD   +  T   P  +L+ H   V         + V+++SWD T  L+D++     
Sbjct: 58  PRKDGD---EDETWGGPRRTLQGHSHFVSDVSLSADSRYVLSSSWDATLRLWDIKKGNTT 228

Query: 319 HSLTGHDQELTHCCTHPTQRLVVTSSRDTTFRLWDFRDPSIHSVNVFQGHTDTVTSAVFT 378
                H ++       P  R + +  RD   ++W+       +V+    H D VT   F 
Sbjct: 229 RRFISHTRDALAVAFSPDNRQIASGGRDKALKIWNTVGECKFTVDA-NSHQDWVTCVKFH 405

Query: 379 VGDN---VVSGSDDRTVKVWDLKNMRSPIATIRTDSAINRINVCVGQKIIA 426
                  VVS S D+T+KVWD + M      +   + IN I++ +    +A
Sbjct: 406 QDAKSPLVVSASMDKTIKVWDNQTMTLKHTFVGHKTQINAIDLALKTYYLA 558

 Score = 45.1 bits (105), Expect = 6e-05,   Method: Compositional matrix adjust.
 Identities = 56/258 (21%), Positives = 96/258 (37%), Gaps = 3/258 (1%)
 Frame = +1

Query: 154 GHRDGIWDVSVTRTQPIVLGTASADHTALLWSIETGKCLVKYAGHVGSVNSIKFHPSEQL 213
           GH   + DVS++     VL ++S D T  LW I+ G    ++  H     ++ F P  + 
Sbjct: 115 GHSHFVSDVSLSADSRYVL-SSSWDATLRLWDIKKGNTTRRFISHTRDALAVAFSPDNRQ 291

Query: 214 ALTASGDQTAHIWRYVVQLPTPQPVADTSQQISGEDEIECSDKDEPDIDGDVSSDCPTVR 273
             +   D+   IW  V                      EC    +  +D +   D     
Sbjct: 292 IASGGRDKALKIWNTVG---------------------EC----KFTVDANSHQDW---- 384

Query: 274 VPLTSLKSHQGVVIAADWLVGGKQVVTASWDRTANLYDVETSELVHSLTGHDQELTHCCT 333
             +T +K HQ              VV+AS D+T  ++D +T  L H+  GH  ++     
Sbjct: 385 --VTCVKFHQDA--------KSPLVVSASMDKTIKVWDNQTMTLKHTFVGHKTQINAIDL 534

Query: 334 HPTQRLVVTSSRDTTFRLWDFRDPSIHSVNVFQGHTDT---VTSAVFTVGDNVVSGSDDR 390
                 + + S+D     W+ ++ +      F G  D    V +  F+     +      
Sbjct: 535 ALKTYYLASGSKDGIVMTWNIQNGT------FLGKIDCDCEVNAVKFSPNKYWLFVGTSE 696

Query: 391 TVKVWDLKNMRSPIATIR 408
            +++WDL N +  I  IR
Sbjct: 697 GIQIWDLPNQKK-IKDIR 747
>27465
          Length = 658

 Score = 53.1 bits (126), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 31/109 (28%), Positives = 55/109 (50%), Gaps = 2/109 (1%)
 Frame = -1

Query: 295 GKQVVTASWDRTANLYDVETSELVHSLTGHDQELTHCC-THPTQRLVVTSSRDTTFRLWD 353
           G   +T S+DRT  ++D  ++E +H+L GH   +      +P    V+T S D T +LW 
Sbjct: 325 GSSFITGSYDRTCKIWDTASAEELHTLEGHRNVVYAIAFNNPFGDKVITGSFDKTCKLWS 146

Query: 354 FRDPSIHSVNVFQGHTDTVTSAVFTVGDNVVS-GSDDRTVKVWDLKNMR 401
             D   +  +  +GHT  +    F     +++ GS D T ++WD++  +
Sbjct: 145 TADGKCY--HTLRGHTAEIVCVSFNPSSTLIATGSMDTTCRLWDVEKAQ 5

 Score = 53.1 bits (126), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 29/79 (36%), Positives = 44/79 (55%), Gaps = 1/79 (1%)
 Frame = -1

Query: 276 LTSLKSHQGVVIAADWL-VGGKQVVTASWDRTANLYDVETSELVHSLTGHDQELTHCCTH 334
           L +L+ H+ VV A  +    G +V+T S+D+T  L+     +  H+L GH  E+     +
Sbjct: 256 LHTLEGHRNVVYAIAFNNPFGDKVITGSFDKTCKLWSTADGKCYHTLRGHTAEIVCVSFN 77

Query: 335 PTQRLVVTSSRDTTFRLWD 353
           P+  L+ T S DTT RLWD
Sbjct: 76  PSSTLIATGSMDTTCRLWD 20

 Score = 48.5 bits (114), Expect = 7e-06,   Method: Compositional matrix adjust.
 Identities = 24/73 (32%), Positives = 34/73 (46%)
 Frame = -1

Query: 154 GHRDGIWDVSVTRTQPIVLGTASADHTALLWSIETGKCLVKYAGHVGSVNSIKFHPSEQL 213
           GHR+ ++ ++        + T S D T  LWS   GKC     GH   +  + F+PS  L
Sbjct: 241 GHRNVVYAIAFNNPFGDKVITGSFDKTCKLWSTADGKCYHTLRGHTAEIVCVSFNPSSTL 62

Query: 214 ALTASGDQTAHIW 226
             T S D T  +W
Sbjct: 61  IATGSMDTTCRLW 23
>18981
          Length = 407

 Score = 52.4 bits (124), Expect = 4e-07,   Method: Compositional matrix adjust.
 Identities = 39/131 (29%), Positives = 68/131 (51%)
 Frame = -2

Query: 296 KQVVTASWDRTANLYDVETSELVHSLTGHDQELTHCCTHPTQRLVVTSSRDTTFRLWDFR 355
             +++A+ DRT  ++ ++ + L+H+L GH+ ++   C +   R VV+ S D T  +W+  
Sbjct: 385 NMIISAATDRTLRVWCLKNTCLLHTLRGHNDDVECVCIYG--RRVVSGSWDKTLIVWEV- 215

Query: 356 DPSIHSVNVFQGHTDTVTSAVFTVGDNVVSGSDDRTVKVWDLKNMRSPIATIRTDSAINR 415
             +   V+   GHT+ +T+  F  G   VSGS D  V+ W L   +  + T+ T   I  
Sbjct: 214 -DTGRPVHQLHGHTEAITAVQFDEG-KAVSGSADGDVRTWALDTGQC-LLTMTTGQDIEV 44

Query: 416 INVCVGQKIIA 426
             V   Q++IA
Sbjct: 43  YCVVYNQEVIA 11

 Score = 37.0 bits (84), Expect = 0.018,   Method: Compositional matrix adjust.
 Identities = 20/60 (33%), Positives = 33/60 (55%)
 Frame = -2

Query: 293 VGGKQVVTASWDRTANLYDVETSELVHSLTGHDQELTHCCTHPTQRLVVTSSRDTTFRLW 352
           + G++VV+ SWD+T  +++V+T   VH L GH + +T       +   V+ S D   R W
Sbjct: 274 IYGRRVVSGSWDKTLIVWEVDTGRPVHQLHGHTEAIT--AVQFDEGKAVSGSADGDVRTW 101

 Score = 33.5 bits (75), Expect = 0.21,   Method: Compositional matrix adjust.
 Identities = 22/94 (23%), Positives = 47/94 (50%), Gaps = 4/94 (4%)
 Frame = -2

Query: 131 SKIVSSFKTTTSRAICQ----LVKEYIGHRDGIWDVSVTRTQPIVLGTASADHTALLWSI 186
           + I+S+    T R  C     L+    GH D +  V +   + +   + S D T ++W +
Sbjct: 385 NMIISAATDRTLRVWCLKNTCLLHTLRGHNDDVECVCIYGRRVV---SGSWDKTLIVWEV 215

Query: 187 ETGKCLVKYAGHVGSVNSIKFHPSEQLALTASGD 220
           +TG+ + +  GH  ++ +++F   + ++ +A GD
Sbjct: 214 DTGRPVHQLHGHTEAITAVQFDEGKAVSGSADGD 113
>02147
          Length = 1547

 Score = 50.8 bits (120), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 58/287 (20%), Positives = 103/287 (35%), Gaps = 40/287 (13%)
 Frame = +2

Query: 149 VKEYIGHRDGIWDVSVTRTQPIVLGTASADHTALLWSIETGKCLVKYAGHVGSVNSIKFH 208
           +  + GH+  +W  ++ R +     T +AD +A +W  E G+ L  ++ H   V S+ F 
Sbjct: 152 IGTFEGHKGAVWGATLNR-EATRAATGAADFSAKIWDAEKGEELQTFS-HKHIVKSVDFS 325

Query: 209 PSEQLALTASGDQTAHIWRYVVQLPTPQPVADTSQQISGEDEIECSDKDEPDIDGDVSSD 268
                 LT S ++   ++  V     P+  A  +  I G                     
Sbjct: 326 HDGTALLTGSNEKLLKVFDLVNTDAEPKSFAGHTSNIKG--------------------- 442

Query: 269 CPTVRVPLTSLKSHQGVVIAADWLVGGKQVVTASWDRTANLYDVETSELVHSLT------ 322
                               A +L  GK++++AS D+T  L+ +ET + V  LT      
Sbjct: 443 --------------------ALFLSDGKRIISASDDKTVRLWSLETCQEVQQLTFDTPPT 562

Query: 323 -------------GHDQEL--------------------THCCTHPTQRLVVTSSRDTTF 349
                         H Q +                    +    H ++R  V    D  F
Sbjct: 563 SLTLSPDKNTIIVTHSQNIAFYQADTLREMKKFEAEAPISSASLHQSERFFVAGGED--F 736

Query: 350 RLWDFRDPSIHSVNVFQGHTDTVTSAVFTV-GDNVVSGSDDRTVKVW 395
           +++ F   +   +  F+GH   V    F+  G+   SGS+D T+++W
Sbjct: 737 KMYKFDYETGKEIESFKGHFGPVHCVRFSPDGELYASGSEDGTLRLW 877

 Score = 47.0 bits (110), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 46/208 (22%), Positives = 85/208 (40%), Gaps = 10/208 (4%)
 Frame = +2

Query: 276 LTSLKSHQGVVIAADWLVGGKQVVTASWDRTANLYDVETSELVHSLTGHDQELTHCCTHP 335
           + + + H+G V  A       +  T + D +A ++D E  E + + + H   +       
Sbjct: 152 IGTFEGHKGAVWGATLNREATRAATGAADFSAKIWDAEKGEELQTFS-HKHIVKSVDFSH 328

Query: 336 TQRLVVTSSRDTTFRLWDFRDPSIHSVNVFQGHTDTVTSAVF-TVGDNVVSGSDDRTVKV 394
               ++T S +   +++D  +      + F GHT  +  A+F + G  ++S SDD+TV++
Sbjct: 329 DGTALLTGSNEKLLKVFDLVNTDAEPKS-FAGHTSNIKGALFLSDGKRIISASDDKTVRL 505

Query: 395 WDLK--------NMRSPIATIRTDSAINRINVCVGQKIIALPHDN-RQVRLFDMSGVRLA 445
           W L+           +P  ++      N I V   Q I     D  R+++ F+      A
Sbjct: 506 WSLETCQEVQQLTFDTPPTSLTLSPDKNTIIVTHSQNIAFYQADTLREMKKFE------A 667

Query: 446 RLPRSSRQGHRRMVCCSAWSEDHPICNL 473
             P SS   H+      A  ED  +   
Sbjct: 668 EAPISSASLHQSERFFVAGGEDFKMYKF 751

 Score = 37.4 bits (85), Expect = 0.013,   Method: Compositional matrix adjust.
 Identities = 16/53 (30%), Positives = 27/53 (50%)
 Frame = +2

Query: 178 DHTALLWSIETGKCLVKYAGHVGSVNSIKFHPSEQLALTASGDQTAHIWRYVV 230
           D     +  ETGK +  + GH G V+ ++F P  +L  + S D T  +W+  +
Sbjct: 731 DFKMYKFDYETGKEIESFKGHFGPVHCVRFSPDGELYASGSEDGTLRLWQTTI 889
>12960
          Length = 550

 Score = 49.7 bits (117), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 28/93 (30%), Positives = 44/93 (47%)
 Frame = +2

Query: 148 LVKEYIGHRDGIWDVSVTRTQPIVLGTASADHTALLWSIETGKCLVKYAGHVGSVNSIKF 207
            +K YIGH   + D   +     +  +   D T +L+ + +G+ L KY  H G+VN +KF
Sbjct: 275 FLKTYIGHGHEVLDAQGSGDNSQIC-SGGIDKTVVLFDVASGQALRKYRDHAGTVNCVKF 451

Query: 208 HPSEQLALTASGDQTAHIWRYVVQLPTPQPVAD 240
           +    + L+ S D T   W    +  TP  V D
Sbjct: 452 NEESTVILSGSLDNTVRAWDTRSRSHTPIQVLD 550

 Score = 35.0 bits (79), Expect = 0.079,   Method: Compositional matrix adjust.
 Identities = 30/132 (22%), Positives = 55/132 (41%), Gaps = 2/132 (1%)
 Frame = +2

Query: 278 SLKSHQGVVIAADWLVGGKQVVTASWDRTANLYDVETSELVHSLTGHDQELTHCCTHPTQ 337
           ++   Q  V A  + V  +  +T   D++  L++      + +  GH  E+         
Sbjct: 158 TINCKQQAVRAVRFSVDSRYCMTCGSDKSVKLWNPHRELFLKTYIGHGHEVLDAQGSGDN 337

Query: 338 RLVVTSSRDTTFRLWDFRDPSIHSVNVFQGHTDTVTSAVFTVGDNVV-SGSDDRTVKVWD 396
             + +   D T  L+D    S  ++  ++ H  TV    F     V+ SGS D TV+ WD
Sbjct: 338 SQICSGGIDKTVVLFDV--ASGQALRKYRDHAGTVNCVKFNEESTVILSGSLDNTVRAWD 511

Query: 397 LKNM-RSPIATI 407
            ++   +PI  +
Sbjct: 512 TRSRSHTPIQVL 547
>17602
          Length = 481

 Score = 47.8 bits (112), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 31/125 (24%), Positives = 59/125 (47%), Gaps = 3/125 (2%)
 Frame = +3

Query: 276 LTSLKSHQGVVIAADWLVGGKQVVTASWDRTANLYDVETSELVHSLTGHDQE-LTHCCTH 334
           L +L +H   V A  +   G  +V++S+D    ++D  + + + +L   D   ++     
Sbjct: 33  LKTLPAHSDPVTAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLXTLIDDDNPPVSFVKFS 212

Query: 335 PTQRLVVTSSRDTTFRLWDFRDPSIHSVNVFQGHTDTVTSAVFTV--GDNVVSGSDDRTV 392
           P  + ++ ++ D T +LWD+         V   +      A F+V  G  +VSGS+D  V
Sbjct: 213 PNGKYILAATLDNTLKLWDYSKGKCLKTYVGHRNEKYCIFANFSVTGGKWIVSGSEDNMV 392

Query: 393 KVWDL 397
            +W+L
Sbjct: 393 YIWNL 407

 Score = 40.4 bits (93), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 39/178 (21%), Positives = 67/178 (37%), Gaps = 4/178 (2%)
 Frame = +3

Query: 183 LWSIETGKCLVKYAGHVGSVNSIKFHPSEQLALTASGDQTAHIWRYVVQLPTPQPVADTS 242
           +W ++TGKCL     H   V ++ F+    L +++S D    IW             DT+
Sbjct: 6   IWDVKTGKCLKTLPAHSDPVTAVHFNRDGSLIVSSSYDGLCRIW-------------DTA 146

Query: 243 QQISGEDEIECSDKDEPDIDGDVSSDCPTVRVPLTSLKSHQGVVIAADWLVGGKQVVTAS 302
              SG+      D D P               P++ +K              GK ++ A+
Sbjct: 147 ---SGQCLXTLIDDDNP---------------PVSFVKFSP----------NGKYILAAT 242

Query: 303 WDRTANLYDVETSELVHSLTGHDQELTHCC----THPTQRLVVTSSRDTTFRLWDFRD 356
            D T  L+D    + + +  GH  E  +C     +    + +V+ S D    +W+  D
Sbjct: 243 LDNTLKLWDYSKGKCLKTYVGHRNE-KYCIFANFSVTGGKWIVSGSEDNMVYIWNLLD 413

 Score = 32.7 bits (73), Expect = 0.34,   Method: Compositional matrix adjust.
 Identities = 21/83 (25%), Positives = 38/83 (45%), Gaps = 1/83 (1%)
 Frame = +3

Query: 147 QLVKEYIGHRDGIWDVSVTRTQPIVLGTASADHTALLWSIETGKCLVKYAGHVGS-VNSI 205
           + +K    H D +  V   R   +++ ++S D    +W   +G+CL          V+ +
Sbjct: 27  KCLKTLPAHSDPVTAVHFNRDGSLIV-SSSYDGLCRIWDTASGQCLXTLIDDDNPPVSFV 203

Query: 206 KFHPSEQLALTASGDQTAHIWRY 228
           KF P+ +  L A+ D T  +W Y
Sbjct: 204 KFSPNGKYILAATLDNTLKLWDY 272

 Score = 31.6 bits (70), Expect = 0.81,   Method: Compositional matrix adjust.
 Identities = 19/60 (31%), Positives = 27/60 (45%), Gaps = 3/60 (5%)
 Frame = +3

Query: 175 ASADHTALLWSIETGKCLVKYAGHVGSVNSIKFHPS---EQLALTASGDQTAHIWRYVVQ 231
           A+ D+T  LW    GKCL  Y GH      I  + S    +  ++ S D   +IW  + Q
Sbjct: 237 ATLDNTLKLWDYSKGKCLKTYVGHRNEKYCIFANFSVTGGKWIVSGSEDNMVYIWNLLDQ 416
>26107
          Length = 1338

 Score = 47.4 bits (111), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 46/166 (27%), Positives = 66/166 (39%), Gaps = 35/166 (21%)
 Frame = -3

Query: 268  DCPTVRVPLTSLKSHQGVVIAADWLVGGKQVVTASWDRTANLYDVETSELVHSLTGHD-- 325
            D PTV        +H   V    W+    Q +TAS D+T  L+DVET+  V +  GH   
Sbjct: 1120 DSPTVH----RWXAHNNAVFDYSWISNDSQCLTASGDQTVALWDVETTTKVTTFIGHKCS 953

Query: 326  -QELTHCCTHPTQRLVVTSSRDTTFRLWDFR-------DP--SIHSVNVFQGH------- 368
             + +  C + P Q    + +RD    LWD R        P   +H V    GH       
Sbjct: 952  VRSVASCPSSPAQ--CASGARDGHIMLWDSRVNKKREHQPCSQVHQVCPQSGHQSKPAKH 779

Query: 369  --------------TDTVTSAVFTVGDNVV--SGSDDRTVKVWDLK 398
                          T    + V    DN++  SG++D  VK+WD +
Sbjct: 778  RRIHRAAGPKGVMDTQQSVTCVLYQTDNLIISSGANDGCVKMWDTR 641

 Score = 41.2 bits (95), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 76/312 (24%), Positives = 126/312 (40%), Gaps = 23/312 (7%)
 Frame = -3

Query: 149  VKEYIGHRDGIWDVSVTRTQPIVLGTASADHTALLWSIETGKCLVKYAGHVGSVNSIKFH 208
            V  +  H + ++D S        L TAS D T  LW +ET   +  + GH  SV S+   
Sbjct: 1108 VHRWXAHNNAVFDYSWISNDSQCL-TASGDQTVALWDVETTTKVTTFIGHKCSVRSVASC 932

Query: 209  PSEQLALTASGDQTAHIWRY---VVQLPTPQPVADTSQQISGEDEIECSDKDEPDIDGDV 265
            PS   A  ASG +  HI  +   V +    QP +   Q        +   + +P     +
Sbjct: 931  PSSP-AQCASGARDGHIMLWDSRVNKKREHQPCSQVHQVCP-----QSGHQSKPAKHRRI 770

Query: 266  SSDCPTVRVPLTSLKSHQGVVIAADWLV---GGKQVVTASWDRTANLYDVETSEL---VH 319
                    V + + +S   V+   D L+   G        WD T   Y   T+ L   VH
Sbjct: 769  HRAAGPKGV-MDTQQSVTCVLYQTDNLIISSGANDGCVKMWD-TRKWYTNTTTSLPVPVH 596

Query: 320  SL--TGHDQEL----THCCTHPTQRLVVTSSRDTTFRLW---DFRDPSIHSVNVFQGH-- 368
            +    GH + L    T C      +L V+ + +  +R      +R+P  +   V+ GH  
Sbjct: 595  TFDYPGHMRRLKGIVTMCMDPWKSQLFVSYTDNKVYRYQLAGQYREPQEY---VYAGHRN 425

Query: 369  -TDTVTSAVFTVGDNVVSGSDDRTVKVWDL-KNMRSPIATIRTDSAINRINVCVGQKI-I 425
             T  V  A+   G  ++SGS   T  +W++ K  + P+  I     ++ ++ C      +
Sbjct: 424  DTFFVRCAISPDGKYLLSGSGRNTGVIWEVDKPNKRPLFLIGHTEDVSAVDWCSTDVCKL 245

Query: 426  ALPHDNRQVRLF 437
            A   D+R +R++
Sbjct: 244  ATVSDDRSLRIW 209
>01805
          Length = 2124

 Score = 47.4 bits (111), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 27/73 (36%), Positives = 35/73 (47%), Gaps = 1/73 (1%)
 Frame = -1

Query: 154 GHRDGIWDVSVTRTQPIVLGTASADHTALLWSIETGKCLVKYAGHVGSVNSIKFHP-SEQ 212
           GH   + D+S  R    VL +ASAD T  LW +  GK  + +  H   V    +HP  EQ
Sbjct: 582 GHTQAVLDLSWNRNARHVLASASADTTVALWDLSEGKMAMNFTQHSREVQCCNWHPQEEQ 403

Query: 213 LALTASGDQTAHI 225
             LT S D T  +
Sbjct: 402 TLLTGSFDNTVKV 364

 Score = 35.0 bits (79), Expect = 0.063,   Method: Compositional matrix adjust.
 Identities = 36/167 (21%), Positives = 68/167 (40%), Gaps = 45/167 (26%)
 Frame = -1

Query: 278 SLKSHQGVVIAADWLVGGKQVV-TASWDRTANLYDVETSELVHSLTGHDQELTHCCTHP- 335
           S+  H   V+   W    + V+ +AS D T  L+D+   ++  + T H +E+  C  HP 
Sbjct: 591 SVTGHTQAVLDLSWNRNARHVLASASADTTVALWDLSEGKMAMNFTQHSREVQCCNWHPQ 412

Query: 336 TQRLVVTSSRDTTFRLWDFRDP-SIHSVNVFQGHTDTVT--------------------- 373
            ++ ++T S D T ++ D R   + H     +G  +                        
Sbjct: 411 EEQTLLTGSFDNTVKVVDCRSAETCHKSWTVEGEVEKAVWNHHNPLQLLACTDKGMVYCF 232

Query: 374 -----SAVFTVGDN----------------VVSGSDDRTVKVWDLKN 399
                  VF+VG +                +++ S+D+T+KVWD+++
Sbjct: 231 DIRHEKPVFSVGAHSSCVTGVCLSSQIPGLMITTSEDKTMKVWDIQD 91
>03387
          Length = 1891

 Score = 46.6 bits (109), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 48/205 (23%), Positives = 89/205 (43%), Gaps = 14/205 (6%)
 Frame = +1

Query: 264 DVSSDCPTVRVPLTSLKSHQGVVIAADWLVG-GKQVVTASWDRTANLYDVETSEL----- 317
           D S +C    +P   LK HQ       W       +++AS D T  L+D+ +++      
Sbjct: 316 DPSGEC----IPELRLKGHQKEGYGLSWNPNLNGHLLSASDDHTICLWDINSTQRESRVV 483

Query: 318 -VHSL-TGHDQELTHCCTHPT-QRLVVTSSRDTTFRLWDFR-DPSIHSVNVFQGHTDTVT 373
             H++ TGH   +     H   + L  + + D    +WD R + +    +V   HT  V 
Sbjct: 484 DAHTIFTGHTSVVEDVAWHLLHESLFGSVADDQKLMIWDTRSNTTSKPSHVVDAHTAEVN 663

Query: 374 SAVFTVGDNVV--SGSDDRTVKVWDLKNMRSPIATIRT--DSAINRINVCVGQKIIALPH 429
              F      +  +GS D+TV +WDL+N++  + +  +  D           + I+A   
Sbjct: 664 CLSFNPYSEFILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSG 843

Query: 430 DNRQVRLFDMSGVRLARLPRSSRQG 454
            +R++ ++D+S +   +LP  +  G
Sbjct: 844 TDRRLHVWDLSKIGEEQLPEDAEDG 918

 Score = 33.9 bits (76), Expect = 0.14,   Method: Compositional matrix adjust.
 Identities = 19/67 (28%), Positives = 31/67 (46%), Gaps = 2/67 (2%)
 Frame = +1

Query: 162 VSVTRTQPIVLGTASADHTALLWSIETGKC-LVKYAGHVGSVNSIKFHPSEQLALTASG- 219
           +S       +L T SAD T  LW +   K  L  +  H   +  +++ P  +  L +SG 
Sbjct: 667 LSFNPYSEFILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGT 846

Query: 220 DQTAHIW 226
           D+  H+W
Sbjct: 847 DRRLHVW 867

 Score = 30.8 bits (68), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 53/250 (21%), Positives = 85/250 (34%), Gaps = 24/250 (9%)
 Frame = +1

Query: 172 LGTASADHTALLWSIETGK-------CLVKYAGHVGSVNSIKFH-PSEQLALTASGDQTA 223
           L +AS DHT  LW I + +           + GH   V  + +H   E L  + + DQ  
Sbjct: 409 LLSASDDHTICLWDINSTQRESRVVDAHTIFTGHTSVVEDVAWHLLHESLFGSVADDQKL 588

Query: 224 HIWRYVVQLPTPQPVADTSQQISGEDEIECSDKDEPDIDGDVSSDCPTVRVPLTSLKSHQ 283
            IW             DT    + +                   D  T  V   S   + 
Sbjct: 589 MIW-------------DTRSNTTSKPSHVV--------------DAHTAEVNCLSFNPYS 687

Query: 284 GVVIAADWLVGGKQVVTASWDRTANLYDVETSEL-VHSLTGHDQELTHCCTHPTQRLVVT 342
             ++A           T S D+T  L+D+   +L +HS   H  E+      P    ++ 
Sbjct: 688 EFILA-----------TGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPHNETILA 834

Query: 343 SS-RDTTFRLWDF------------RDPSIHSVNVFQGHTDTVTSAVFTVGDN--VVSGS 387
           SS  D    +WD              D     + +  GHT  ++   +   +   V S S
Sbjct: 835 SSGTDRRLHVWDLSKIGEEQLPEDAEDGPPELLFIHGGHTAKISDFSWNPNEPWIVCSVS 1014

Query: 388 DDRTVKVWDL 397
           +D  ++VW +
Sbjct: 1015EDNIMQVWQM 1044
>19949
          Length = 903

 Score = 46.6 bits (109), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 33/119 (27%), Positives = 55/119 (46%), Gaps = 3/119 (2%)
 Frame = +2

Query: 286 VIAADWLVGGKQVVTASWDRTANLYDVETSELVHSLTGHDQELTHCCTH--PTQRLVVTS 343
           V + D+   G    + S D    L+D+     +++  GH   +  CC    P  R + ++
Sbjct: 2   VKSLDFHPYGAYTASGSMDCNVKLWDIRRKGCIYTYKGHTGCV--CCLRFSPDGRWIASA 175

Query: 344 SRDTTFRLWDFRDPSIHSVNVFQGHTDTVTSAVFTVGDNVV-SGSDDRTVKVWDLKNMR 401
           S D   +LWD     +  +   + H D V +  F   + ++ SGS DRTVK WDL+  +
Sbjct: 176 SEDGLVKLWDLTAGKL--LTDLKLHRDAVNTIEFHPHEFLLASGSADRTVKFWDLETFQ 346

 Score = 45.8 bits (107), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 21/55 (38%), Positives = 29/55 (52%)
 Frame = +2

Query: 172 LGTASADHTALLWSIETGKCLVKYAGHVGSVNSIKFHPSEQLALTASGDQTAHIW 226
           + +AS D    LW +  GK L     H  +VN+I+FHP E L  + S D+T   W
Sbjct: 164 IASASEDGLVKLWDLTAGKLLTDLKLHRDAVNTIEFHPHEFLLASGSADRTVKFW 328

 Score = 44.3 bits (103), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 30/112 (26%), Positives = 49/112 (43%), Gaps = 1/112 (0%)
 Frame = +2

Query: 334 HPTQRLVVTSSRDTTFRLWDFRDPSIHSVNVFQGHTDTVTSAVFTV-GDNVVSGSDDRTV 392
           HP      + S D   +LWD R      +  ++GHT  V    F+  G  + S S+D  V
Sbjct: 20  HPYGAYTASGSMDCNVKLWDIRRKGC--IYTYKGHTGCVCCLRFSPDGRWIASASEDGLV 193

Query: 393 KVWDLKNMRSPIATIRTDSAINRINVCVGQKIIALPHDNRQVRLFDMSGVRL 444
           K+WDL   +          A+N I     + ++A    +R V+ +D+   +L
Sbjct: 194 KLWDLTAGKLLTDLKLHRDAVNTIEFHPHEFLLASGSADRTVKFWDLETFQL 349

 Score = 42.7 bits (99), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 31/121 (25%), Positives = 57/121 (47%), Gaps = 1/121 (0%)
 Frame = +2

Query: 276 LTSLKSHQGVVIAADWLVGGKQVVTASWDRTANLYDVETSELVHSLTGHDQELTHCCTHP 335
           + + K H G V    +   G+ + +AS D    L+D+   +L+  L  H   +     HP
Sbjct: 98  IYTYKGHTGCVCCLRFSPDGRWIASASEDGLVKLWDLTAGKLLTDLKLHRDAVNTIEFHP 277

Query: 336 TQRLVVTSSRDTTFRLWDFRDPSIHSVNVFQGHTDTVTSAVFTV-GDNVVSGSDDRTVKV 394
            + L+ + S D T + WD    +   ++  +   +++ S +F   G  + SGS D T+KV
Sbjct: 278 HEFLLASGSADRTVKFWDLE--TFQLISTTEPEANSIRSILFHPDGVCLYSGSKD-TLKV 448

Query: 395 W 395
           +
Sbjct: 449 Y 451

 Score = 42.0 bits (97), Expect = 6e-04,   Method: Compositional matrix adjust.
 Identities = 37/175 (21%), Positives = 58/175 (33%)
 Frame = +2

Query: 173 GTASADHTALLWSIETGKCLVKYAGHVGSVNSIKFHPSEQLALTASGDQTAHIWRYVVQL 232
            + S D    LW I    C+  Y GH G V  ++F P  +   +AS D    +W      
Sbjct: 41  ASGSMDCNVKLWDIRRKGCIYTYKGHTGCVCCLRFSPDGRWIASASEDGLVKLWDL---- 208

Query: 233 PTPQPVADTSQQISGEDEIECSDKDEPDIDGDVSSDCPTVRVPLTSLKSHQGVVIAADWL 292
                                                 T    LT LK H+  V   ++ 
Sbjct: 209 --------------------------------------TAGKLLTDLKLHRDAVNTIEFH 274

Query: 293 VGGKQVVTASWDRTANLYDVETSELVHSLTGHDQELTHCCTHPTQRLVVTSSRDT 347
                + + S DRT   +D+ET +L+ +       +     HP    + + S+DT
Sbjct: 275 PHEFLLASGSADRTVKFWDLETFQLISTTEPEANSIRSILFHPDGVCLYSGSKDT 439

 Score = 34.7 bits (78), Expect = 0.095,   Method: Compositional matrix adjust.
 Identities = 20/74 (27%), Positives = 32/74 (43%)
 Frame = +2

Query: 147 QLVKEYIGHRDGIWDVSVTRTQPIVLGTASADHTALLWSIETGKCLVKYAGHVGSVNSIK 206
           +L+ +   HRD +  +        +L + SAD T   W +ET + +        S+ SI 
Sbjct: 218 KLLTDLKLHRDAVNTIEF-HPHEFLLASGSADRTVKFWDLETFQLISTTEPEANSIRSIL 394

Query: 207 FHPSEQLALTASGD 220
           FHP      + S D
Sbjct: 395 FHPDGVCLYSGSKD 436
>01598
          Length = 1545

 Score = 43.5 bits (101), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 24/89 (26%), Positives = 44/89 (49%), Gaps = 1/89 (1%)
 Frame = +1

Query: 149  VKEYIGHRDGIWDVSVTRTQPIVLGTASADHTALLWSIETGKCLVKYAGHVGSVNSIKFH 208
            ++E  GH   + D+S +      L +   D  A +W ++ G  L ++ GH+G + + +F 
Sbjct: 1279 LRELSGHSQRVTDMSWSPHHDARLVSVGYDAEAFVWDVQKGTALAQFKGHMGRLLTCQFS 1458

Query: 209  PSE-QLALTASGDQTAHIWRYVVQLPTPQ 236
              +  L +T   D + H+WR V Q   P+
Sbjct: 1459 GLDPDLVMTGGSDASVHVWR-VSQQAAPE 1542
>13278
          Length = 870

 Score = 43.5 bits (101), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 21/58 (36%), Positives = 29/58 (50%)
 Frame = +1

Query: 170 IVLGTASADHTALLWSIETGKCLVKYAGHVGSVNSIKFHPSEQLALTASGDQTAHIWR 227
           ++L +AS D T  LW +E G CL     H   V S+ F P  +   + S D+  HIW 
Sbjct: 115 LILASASFDSTVRLWEVERGLCLHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWN 288

 Score = 42.4 bits (98), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 29/106 (27%), Positives = 53/106 (50%), Gaps = 5/106 (4%)
 Frame = +1

Query: 298 VVTASWDRTANLYDVETSELVHSLTGHDQELTHCCTHPTQRLVVTSSRDTTFRLWDFRDP 357
           + +AS+D T  L++VE    +H+LT H + +      P  + + + S D    +W+ +  
Sbjct: 121 LASASFDSTVRLWEVERGLCLHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNVQTG 300

Query: 358 SIHSVNVFQGHTDTVTSAVFTV-----GDNVVSGSDDRTVKVWDLK 398
           S+  V+ ++G     T  +F V     GD V + + D +V V DL+
Sbjct: 301 SL--VHSYKG-----TGGIFEVCWNHRGDKVGASASDGSVFVLDLR 417

 Score = 38.1 bits (87), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 23/80 (28%), Positives = 40/80 (50%)
 Frame = +1

Query: 276 LTSLKSHQGVVIAADWLVGGKQVVTASWDRTANLYDVETSELVHSLTGHDQELTHCCTHP 335
           L +L  HQ  V +  +   GK + + S+D+  ++++V+T  LVHS  G       C  H 
Sbjct: 181 LHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNVQTGSLVHSYKGTGGIFEVCWNHR 360

Query: 336 TQRLVVTSSRDTTFRLWDFR 355
             ++  ++S  + F L D R
Sbjct: 361 GDKVGASASDGSVFVL-DLR 417
>10264
          Length = 416

 Score = 43.5 bits (101), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 24/89 (26%), Positives = 44/89 (49%), Gaps = 1/89 (1%)
 Frame = -1

Query: 149 VKEYIGHRDGIWDVSVTRTQPIVLGTASADHTALLWSIETGKCLVKYAGHVGSVNSIKFH 208
           ++E  GH   + D+S +      L +   D  A +W ++ G  L ++ GH+G + + +F 
Sbjct: 266 LRELSGHSQRVTDMSWSPHHDARLVSVGYDAEAFVWDVQKGTALAQFKGHMGRLLTCQFS 87

Query: 209 PSE-QLALTASGDQTAHIWRYVVQLPTPQ 236
             +  L +T   D + H+WR V Q   P+
Sbjct: 86  GLDPDLVMTGGSDASVHVWR-VSQQAAPE 3
>30295
          Length = 593

 Score = 43.1 bits (100), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 27/121 (22%), Positives = 51/121 (42%), Gaps = 2/121 (1%)
 Frame = +2

Query: 278 SLKSHQGVVIAADWLVGGKQVVTASWDRTANLYDVETSELVHSLTGHDQELTHCCTHPTQ 337
           +L+ H   + A  W    + +V+AS D    ++D  T+  VH++      +  C   P+ 
Sbjct: 230 TLRXHLAKIYAMHWATDSRNLVSASQDGKLIVWDGYTTNKVHAIPLRSSWVMTCAYAPSG 409

Query: 338 RLVVTSSRDTTFRLWDF--RDPSIHSVNVFQGHTDTVTSAVFTVGDNVVSGSDDRTVKVW 395
             V     D    ++    R+ ++       GHT  ++   F   + +V+ S D T  +W
Sbjct: 410 GYVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFIDDNQIVTSSGDMTCALW 589

Query: 396 D 396
           D
Sbjct: 590 D 592
>03395
          Length = 2795

 Score = 42.7 bits (99), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 36/163 (22%), Positives = 67/163 (41%), Gaps = 4/163 (2%)
 Frame = +2

Query: 198 HVGSVNSIKFHPSEQLALTASGDQTAHIWRYVVQLPTPQPVADTSQQ---ISGEDEIECS 254
           H G V +I+ H +++  ++AS D +  IW  +    +   +A+T  +     G+D    +
Sbjct: 143 HKGKVTAIQIHTNDRCCVSASTDGSTIIWDLITNTRSQIVLANTLFKCVCFGGKDLHILT 322

Query: 255 DKDEPDIDGDVSSDCPTVRVPLTSLKSHQ-GVVIAADWLVGGKQVVTASWDRTANLYDVE 313
              +  I      D   +R     L+  Q G +   D    G+ ++T   D    L+   
Sbjct: 323 SGTDHKIGYWEVGDGGLLR----ELEGSQTGAINTIDIDRDGQTILTGGEDSLLKLWRYN 490

Query: 314 TSELVHSLTGHDQELTHCCTHPTQRLVVTSSRDTTFRLWDFRD 356
             E+ H+  GH  ++T     P +  +V+   D    +W F D
Sbjct: 491 EGEVTHTGIGHSNQITKARICPNRHYIVSGGEDGALHIWKFPD 619

 Score = 28.1 bits (61), Expect = 7.5,   Method: Compositional matrix adjust.
 Identities = 19/82 (23%), Positives = 33/82 (40%), Gaps = 1/82 (1%)
 Frame = +2

Query: 148 LVKEYIGHRDG-IWDVSVTRTQPIVLGTASADHTALLWSIETGKCLVKYAGHVGSVNSIK 206
           L++E  G + G I  + + R    +L T   D    LW    G+      GH   +   +
Sbjct: 371 LLRELEGSQTGAINTIDIDRDGQTIL-TGGEDSLLKLWRYNEGEVTHTGIGHSNQITKAR 547

Query: 207 FHPSEQLALTASGDQTAHIWRY 228
             P+    ++   D   HIW++
Sbjct: 548 ICPNRHYIVSGGEDGALHIWKF 613
>19863
          Length = 502

 Score = 42.4 bits (98), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 23/88 (26%), Positives = 41/88 (46%)
 Frame = +1

Query: 172 LGTASADHTALLWSIETGKCLVKYAGHVGSVNSIKFHPSEQLALTASGDQTAHIWRYVVQ 231
           L + S+D + ++W +E G   ++  GH G VN + F   +   L+ S D T  IW   ++
Sbjct: 16  LVSGSSDMSIVVWDVENGVQKLRLQGHAGWVNDVHFSQDQCWLLSCSNDNTVRIWN--IE 189

Query: 232 LPTPQPVADTSQQISGEDEIECSDKDEP 259
                P+    ++  G    +CS   +P
Sbjct: 190 ESDQIPIVMEHKRAQGLKVTKCSKCGKP 273

 Score = 28.5 bits (62), Expect = 6.4,   Method: Compositional matrix adjust.
 Identities = 17/62 (27%), Positives = 29/62 (46%)
 Frame = +1

Query: 295 GKQVVTASWDRTANLYDVETSELVHSLTGHDQELTHCCTHPTQRLVVTSSRDTTFRLWDF 354
           G Q+V+ S D +  ++DVE       L GH   +        Q  +++ S D T R+W+ 
Sbjct: 7   GLQLVSGSSDMSIVVWDVENGVQKLRLQGHAGWVNDVHFSQDQCWLLSCSNDNTVRIWNI 186

Query: 355 RD 356
            +
Sbjct: 187 EE 192
>12574
          Length = 521

 Score = 40.4 bits (93), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 23/72 (31%), Positives = 35/72 (48%)
 Frame = +3

Query: 147 QLVKEYIGHRDGIWDVSVTRTQPIVLGTASADHTALLWSIETGKCLVKYAGHVGSVNSIK 206
           +  K   GH+ G+ DV+ +    + L +AS D T  +W   TGKC+    GH   V    
Sbjct: 285 KFEKTIAGHKLGLSDVAWSSDSKL-LCSASDDKTLKIWEFSTGKCMKTLKGHSNYVFCCN 461

Query: 207 FHPSEQLALTAS 218
           F+P   L ++ S
Sbjct: 462 FNPQSNLIVSGS 497

 Score = 38.5 bits (88), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 27/119 (22%), Positives = 52/119 (43%), Gaps = 1/119 (0%)
 Frame = +3

Query: 270 PTVRVPLTSLKSHQGVVIAADWLVGGKQVVTASWDRTANLYDVETSELVHSLTGHDQELT 329
           PT  +  T L  H   + A  +   G  + ++S D+   ++     +   ++ GH   L+
Sbjct: 150 PTYTLKFT-LAGHTKALSAVKFSPNGDWLASSSADKLIKIWGAYDGKFEKTIAGHKLGLS 326

Query: 330 HCCTHPTQRLVVTSSRDTTFRLWDFRDPSIHSVNVFQGHTDTVTSAVFTVGDN-VVSGS 387
                   +L+ ++S D T ++W+F       +   +GH++ V    F    N +VSGS
Sbjct: 327 DVAWSSDSKLLCSASDDKTLKIWEFSTGKC--MKTLKGHSNYVFCCNFNPQSNLIVSGS 497

 Score = 35.8 bits (81), Expect = 0.042,   Method: Compositional matrix adjust.
 Identities = 21/85 (24%), Positives = 38/85 (44%), Gaps = 1/85 (1%)
 Frame = +3

Query: 314 TSELVHSLTGHDQELTHCCTHPTQRLVVTSSRDTTFRLWDFRDPSIHSVNVFQGHTDTVT 373
           T  L  +L GH + L+     P    + +SS D   ++W   D          GH   ++
Sbjct: 153 TYTLKFTLAGHTKALSAVKFSPNGDWLASSSADKLIKIWGAYDGKFE--KTIAGHKLGLS 326

Query: 374 SAVFTVGDNVV-SGSDDRTVKVWDL 397
              ++    ++ S SDD+T+K+W+ 
Sbjct: 327 DVAWSSDSKLLCSASDDKTLKIWEF 401

 Score = 31.6 bits (70), Expect = 0.81,   Method: Compositional matrix adjust.
 Identities = 17/57 (29%), Positives = 28/57 (49%)
 Frame = +3

Query: 172 LGTASADHTALLWSIETGKCLVKYAGHVGSVNSIKFHPSEQLALTASGDQTAHIWRY 228
           L ++SAD    +W    GK     AGH   ++ + +    +L  +AS D+T  IW +
Sbjct: 231 LASSSADKLIKIWGAYDGKFEKTIAGHKLGLSDVAWSSDSKLLCSASDDKTLKIWEF 401
>01462
          Length = 995

 Score = 40.0 bits (92), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 18/69 (26%), Positives = 37/69 (53%)
 Frame = +2

Query: 287 IAADWLVGGKQVVTASWDRTANLYDVETSELVHSLTGHDQELTHCCTHPTQRLVVTSSRD 346
           IA D  +G +++   + DR  +++D+E  + ++++ GH   +         +  V++S D
Sbjct: 209 IAVDEKMGTRRLYAGAGDRKIHVWDIEAGQYLNAMEGHKDYIHKVVMKNDAQECVSASED 388

Query: 347 TTFRLWDFR 355
            T R+WD R
Sbjct: 389 GTVRMWDIR 415

 Score = 28.9 bits (63), Expect = 5.1,   Method: Compositional matrix adjust.
 Identities = 15/55 (27%), Positives = 24/55 (43%)
 Frame = +2

Query: 172 LGTASADHTALLWSIETGKCLVKYAGHVGSVNSIKFHPSEQLALTASGDQTAHIW 226
           L   + D    +W IE G+ L    GH   ++ +      Q  ++AS D T  +W
Sbjct: 242 LYAGAGDRKIHVWDIEAGQYLNAMEGHKDYIHKVVMKNDAQECVSASEDGTVRMW 406
>19498
          Length = 903

 Score = 39.3 bits (90), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 40/165 (24%), Positives = 62/165 (37%), Gaps = 18/165 (10%)
 Frame = -1

Query: 249 DEIECSDKDEPDIDGDVSSDCPTVRVPLTSLKSHQGVVIAADWLVGGKQVVTASWDRTAN 308
           DE E +D D P +              L  + SH G V    W   GK + +   D+   
Sbjct: 846 DEKEEADDDVPRV--------------LCQMDSHLGCVNCVRWSENGKFLASGGDDKLIM 709

Query: 309 LYDV-----------------ETSELVHSLTGHDQELTHCCTHPTQRLVVTSSRDTTFRL 351
           ++ +                 E    V +L GH  ++      P    + + S D T  +
Sbjct: 708 IWQISRGFGSGKSFGSNVTILEHWRSVATLRGHAGDVLDLAWSPQDLWLASCSVDNTIVV 529

Query: 352 WDFRDPSIHSVNVFQGHTDTVTSAVF-TVGDNVVSGSDDRTVKVW 395
           W+    S   V V +GH   V    +  VG  + S SDD+T++VW
Sbjct: 528 WNALKFS-EQVAVIRGHAGMVKGVTWDPVGRYLASQSDDKTLRVW 397

 Score = 33.1 bits (74), Expect = 0.25,   Method: Compositional matrix adjust.
 Identities = 19/75 (25%), Positives = 39/75 (52%), Gaps = 1/75 (1%)
 Frame = -1

Query: 154 GHRDGIWDVSVTRTQPIVLGTASADHTALLW-SIETGKCLVKYAGHVGSVNSIKFHPSEQ 212
           GH   + D++ +  Q + L + S D+T ++W +++  + +    GH G V  + + P  +
Sbjct: 615 GHAGDVLDLAWS-PQDLWLASCSVDNTIVVWNALKFSEQVAVIRGHAGMVKGVTWDPVGR 439

Query: 213 LALTASGDQTAHIWR 227
              + S D+T  +WR
Sbjct: 438 YLASQSDDKTLRVWR 394

 Score = 30.0 bits (66), Expect = 2.2,   Method: Compositional matrix adjust.
 Identities = 21/82 (25%), Positives = 37/82 (45%), Gaps = 1/82 (1%)
 Frame = -1

Query: 276 LTSLKSHQGVVIAADWLVGGKQVVTASWDRTANLYD-VETSELVHSLTGHDQELTHCCTH 334
           + +L+ H G V+   W      + + S D T  +++ ++ SE V  + GH   +      
Sbjct: 630 VATLRGHAGDVLDLAWSPQDLWLASCSVDNTIVVWNALKFSEQVAVIRGHAGMVKGVTWD 451

Query: 335 PTQRLVVTSSRDTTFRLWDFRD 356
           P  R + + S D T R+W   D
Sbjct: 450 PVGRYLASQSDDKTLRVWRTSD 385
>17298
          Length = 476

 Score = 38.9 bits (89), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 19/56 (33%), Positives = 29/56 (51%)
 Frame = -1

Query: 185 SIETGKCLVKYAGHVGSVNSIKFHPSEQLALTASGDQTAHIWRYVVQLPTPQPVAD 240
           ++ +G+ L KY  H G+VN +KF+    + L+ S D T   W    +  TP  V D
Sbjct: 254 NVASGQALRKYRDHAGTVNCVKFNEESTVILSGSLDNTVRAWDTRSRSHTPIQVLD 87

 Score = 28.1 bits (61), Expect = 9.1,   Method: Compositional matrix adjust.
 Identities = 20/56 (35%), Positives = 30/56 (53%), Gaps = 1/56 (1%)
 Frame = -1

Query: 339 LVVTSSRDTTFRLWDFRDPSIHSVNVFQGHTDTVTSAVFTVGD-NVVSGSDDRTVK 393
           ++++ S D T R WD R  S   + V    TD+VTS    V D  +++GS D  V+
Sbjct: 170 VILSGSLDNTVRAWDTRSRSHTPIQVLDEATDSVTS--IQVSDYEILTGSADGRVR 9
>21105
          Length = 650

 Score = 37.7 bits (86), Expect = 0.012,   Method: Compositional matrix adjust.
 Identities = 16/56 (28%), Positives = 28/56 (50%)
 Frame = +1

Query: 299 VTASWDRTANLYDVETSELVHSLTGHDQELTHCCTHPTQRLVVTSSRDTTFRLWDF 354
           +TA  DR    +D  T +L+H++  H   +T     P    +++ S D + RLW+ 
Sbjct: 112 ITAHEDRHIRFFDNNTGKLIHAMVAHLDSVTSLAVDPNGLYLLSGSHDCSIRLWNL 279

 Score = 35.4 bits (80), Expect = 0.048,   Method: Compositional matrix adjust.
 Identities = 21/65 (32%), Positives = 36/65 (55%), Gaps = 1/65 (1%)
 Frame = +1

Query: 334 HPTQRLVVTSSRDTTFRLWDFRDPSIHSVNVFQGHTDTVTS-AVFTVGDNVVSGSDDRTV 392
           HPT  + +T+  D   R +D     +  ++    H D+VTS AV   G  ++SGS D ++
Sbjct: 91  HPTMPITITAHEDRHIRFFDNNTGKL--IHAMVAHLDSVTSLAVDPNGLYLLSGSHDCSI 264

Query: 393 KVWDL 397
           ++W+L
Sbjct: 265 RLWNL 279

 Score = 29.3 bits (64), Expect = 3.4,   Method: Compositional matrix adjust.
 Identities = 18/60 (30%), Positives = 27/60 (45%)
 Frame = +1

Query: 167 TQPIVLGTASADHTALLWSIETGKCLVKYAGHVGSVNSIKFHPSEQLALTASGDQTAHIW 226
           T PI + TA  D     +   TGK +     H+ SV S+   P+    L+ S D +  +W
Sbjct: 97  TMPITI-TAHEDRHIRFFDNNTGKLIHAMVAHLDSVTSLAVDPNGLYLLSGSHDCSIRLW 273
>26939
          Length = 388

 Score = 37.7 bits (86), Expect = 0.012,   Method: Compositional matrix adjust.
 Identities = 22/62 (35%), Positives = 33/62 (53%), Gaps = 1/62 (1%)
 Frame = +2

Query: 338 RLVVTSSRDTTFRLWDFRDPSIHSVNVFQGHTDTVTSAVF-TVGDNVVSGSDDRTVKVWD 396
           + +V++S D T R+WD R+     +     H    TS  F      V+SGS D+TVKVW+
Sbjct: 5   KYLVSASDDKTIRVWDLRNKR--CMKTLYAHQHFCTSIDFHKAHPYVISGSVDQTVKVWE 178

Query: 397 LK 398
            +
Sbjct: 179 CR 184

 Score = 37.4 bits (85), Expect = 0.015,   Method: Compositional matrix adjust.
 Identities = 17/55 (30%), Positives = 26/55 (47%)
 Frame = +2

Query: 172 LGTASADHTALLWSIETGKCLVKYAGHVGSVNSIKFHPSEQLALTASGDQTAHIW 226
           L +AS D T  +W +   +C+     H     SI FH +    ++ S DQT  +W
Sbjct: 11  LVSASDDKTIRVWDLRNKRCMKTLYAHQHFCTSIDFHKAHPYVISGSVDQTVKVW 175

 Score = 34.3 bits (77), Expect = 0.11,   Method: Composition-based stats.
 Identities = 13/22 (59%), Positives = 18/22 (81%)
 Frame = +2

Query: 380 GDNVVSGSDDRTVKVWDLKNMR 401
           G  +VS SDD+T++VWDL+N R
Sbjct: 2   GKYLVSASDDKTIRVWDLRNKR 67
>17266
          Length = 480

 Score = 37.4 bits (85), Expect = 0.015,   Method: Composition-based stats.
 Identities = 15/53 (28%), Positives = 27/53 (50%)
 Frame = -1

Query: 174 TASADHTALLWSIETGKCLVKYAGHVGSVNSIKFHPSEQLALTASGDQTAHIW 226
           + + D +A LW +  G C   ++GH   +N+I + P+     T S D T  ++
Sbjct: 408 SGACDASAKLWDVRDGMCKQTFSGHESDINAITYFPNGHAFATGSDDATCRLF 250

 Score = 28.1 bits (61), Expect = 9.3,   Method: Composition-based stats.
 Identities = 23/99 (23%), Positives = 40/99 (40%)
 Frame = -1

Query: 384 VSGSDDRTVKVWDLKNMRSPIATIRTDSAINRINVCVGQKIIALPHDNRQVRLFDMSGVR 443
           VSG+ D + K+WD+++          +S IN I         A   D+   RLFD+    
Sbjct: 411 VSGACDASAKLWDVRDGMCKQTFSGHESDINAITYFPNGHAFATGSDDATCRLFDI---- 244

Query: 444 LARLPRSSRQGHRRMVCCSAWSEDHPICNLFTCGFDRQA 482
                R+ ++          +S D+ IC + +  F +  
Sbjct: 243 -----RADQE-------IGMYSHDNIICGITSVAFSKSG 163
>11915
          Length = 737

 Score = 37.0 bits (84), Expect = 0.019,   Method: Compositional matrix adjust.
 Identities = 20/60 (33%), Positives = 30/60 (50%), Gaps = 1/60 (1%)
 Frame = +1

Query: 170 IVLGTASADHTALLWSIETGKCLVKYAGHVGSVNSIKFHPSEQLAL-TASGDQTAHIWRY 228
           +VL T        LW+ ETGK L++   H  +V+ + F     L L +AS D T  +W +
Sbjct: 445 LVLATGHVSGRIKLWNCETGKLLIEMMDHKATVHDLHFAADNSLCLMSASHDGTVKLWEF 624
>15972
          Length = 1069

 Score = 36.6 bits (83), Expect = 0.027,   Method: Compositional matrix adjust.
 Identities = 13/34 (38%), Positives = 21/34 (61%)
 Frame = +3

Query: 320 SLTGHDQELTHCCTHPTQRLVVTSSRDTTFRLWD 353
           + +GH   + H   HP+ +L +T S+D T RLW+
Sbjct: 222 TFSGHKGPVRHLAVHPSGKLTLTVSQDRTLRLWN 323

 Score = 35.4 bits (80), Expect = 0.058,   Method: Compositional matrix adjust.
 Identities = 14/32 (43%), Positives = 20/32 (62%)
 Frame = +3

Query: 195 YAGHVGSVNSIKFHPSEQLALTASGDQTAHIW 226
           ++GH G V  +  HPS +L LT S D+T  +W
Sbjct: 225 FSGHKGPVRHLAVHPSGKLTLTVSQDRTLRLW 320
>04524
          Length = 1340

 Score = 36.2 bits (82), Expect = 0.032,   Method: Compositional matrix adjust.
 Identities = 33/116 (28%), Positives = 53/116 (45%), Gaps = 14/116 (12%)
 Frame = -1

Query: 297  QVVTASWDRTANLYDVETSELVHS------------LTGHDQELTHCCTHPTQRLVVTSS 344
            QV+ A  D+T ++Y   T+  V              L GH   +   C    +  VVT  
Sbjct: 1142 QVIVA--DKTGDVYTFPTTTQVEVKDEGEVKTHGQLLLGHLSMVLDVCLTGREGHVVTCD 969

Query: 345  RDTTFRLWDFRDPSIHSVNVF-QGHTDTVTSAVFTVGDNV-VSGSDDRTVKVWDLK 398
            RD   R+  F  P+ ++++ +  GHT  V   V+     V +SGS D TV+ W+++
Sbjct: 968  RDEKIRVSQF--PNAYNIHTYCLGHTQFVNCLVYVEEFRVLISGSGDCTVRAWNME 807
>07781
          Length = 1269

 Score = 35.8 bits (81), Expect = 0.038,   Method: Compositional matrix adjust.
 Identities = 21/63 (33%), Positives = 35/63 (55%), Gaps = 2/63 (3%)
 Frame = -2

Query: 383 VVSGSDDRTVKVWDLKNMRSPIAT-IRTDSAINRINVCVGQK-IIALPHDNRQVRLFDMS 440
           + SGSDD  +KVWDL+   +P+ T  R    +  I  C  ++ ++A+   +  +RLFD  
Sbjct: 746 IYSGSDDCKLKVWDLRVGTTPVLTNSRFTMGVTSIQSCPQREHLLAVGSYDENLRLFDTR 567

Query: 441 GVR 443
            +R
Sbjct: 566 HMR 558
>19140
          Length = 573

 Score = 35.4 bits (80), Expect = 0.055,   Method: Compositional matrix adjust.
 Identities = 19/52 (36%), Positives = 28/52 (53%), Gaps = 1/52 (1%)
 Frame = -3

Query: 358 SIHSVNVFQGHTDTVTSAVFTV-GDNVVSGSDDRTVKVWDLKNMRSPIATIR 408
           + H +   +GHTD V + V    G   +SGS D T+++W L   R  +AT R
Sbjct: 520 TCHKLMKLKGHTDNVKALVLNRDGTQCLSGSSDGTIRLWSLGQQRC-VATFR 368
>31384
          Length = 474

 Score = 34.7 bits (78), Expect = 0.079,   Method: Compositional matrix adjust.
 Identities = 16/49 (32%), Positives = 30/49 (61%)
 Frame = -1

Query: 280 KSHQGVVIAADWLVGGKQVVTASWDRTANLYDVETSELVHSLTGHDQEL 328
           ++H G V+  DW   G +V TAS D+TA ++D+ +++ +  +  HD  +
Sbjct: 144 QTHTGPVLDVDWSDDGTKVFTASCDKTAKVWDLNSNQCMQ-IAQHDAPV 1
>20662
          Length = 1220

 Score = 34.7 bits (78), Expect = 0.098,   Method: Compositional matrix adjust.
 Identities = 21/77 (27%), Positives = 36/77 (46%), Gaps = 3/77 (3%)
 Frame = +2

Query: 152 YIGHRDGIWDVSVTRTQPIVLGTASADHTALLWSIETGK---CLVKYAGHVGSVNSIKFH 208
           Y  H D +WDV    T+P +  + S D   +LW +   K   CL K +        +++ 
Sbjct: 497 YRAHSDIVWDVQCHPTEPALFLSCSQDGKIVLWDVRESKPATCLPKCSSGFKPT-CVQWQ 673

Query: 209 PSEQLALTASGDQTAHI 225
           P+ +  + A GD+  H+
Sbjct: 674 PNAR-NMYAVGDEGGHV 721
>04088
          Length = 511

 Score = 34.3 bits (77), Expect = 0.12,   Method: Compositional matrix adjust.
 Identities = 20/67 (29%), Positives = 31/67 (46%), Gaps = 2/67 (2%)
 Frame = +3

Query: 295 GKQVVTASWDRTANLYDVETSELVHSLTGH--DQELTHCCTHPTQRLVVTSSRDTTFRLW 352
           G+  + +S D T  L D +T E+++  TGH   Q     C +    LVV+ S D     W
Sbjct: 66  GQCSLVSSQDNTVRLMDKDTGEMLNEFTGHKHSQYKIDSCLNNEDTLVVSGSEDGKVYFW 245

Query: 353 DFRDPSI 359
           D  +  +
Sbjct: 246 DLVEAKL 266

 Score = 29.6 bits (65), Expect = 3.0,   Method: Compositional matrix adjust.
 Identities = 23/60 (38%), Positives = 31/60 (51%), Gaps = 3/60 (5%)
 Frame = +3

Query: 341 VTSSRDTTFRLWDFRDPSIHSVNVFQGHTDT---VTSAVFTVGDNVVSGSDDRTVKVWDL 397
           + SS+D T RL D +D     +N F GH  +   + S +      VVSGS+D  V  WDL
Sbjct: 78  LVSSQDNTVRLMD-KDTG-EMLNEFTGHKHSQYKIDSCLNNEDTLVVSGSEDGKVYFWDL 251
>15118
          Length = 1074

 Score = 34.3 bits (77), Expect = 0.12,   Method: Compositional matrix adjust.
 Identities = 37/176 (21%), Positives = 62/176 (35%), Gaps = 6/176 (3%)
 Frame = +3

Query: 183 LWSIETGKCLVKYA---GHVGSVNSIKFHPSEQLALTASGDQTAHIWRYVVQLPTPQPVA 239
           ++++++GK    +     HV  V  + F     L +TA GD     WR+           
Sbjct: 135 IYNLQSGKHRGSFGDTVAHVSGVRGVAFDAFNCLLITAGGDCDIKFWRF----------- 281

Query: 240 DTSQQISGEDEIECSDKDEPDIDGDVSSDCPTVRVPLTSLKSHQGV---VIAADWLVGGK 296
                           +D               RV L  LK  +G+   ++  D      
Sbjct: 282 --------------GSRDRA-------------RVLLKELKMSEGISRILLHRD----SN 368

Query: 297 QVVTASWDRTANLYDVETSELVHSLTGHDQELTHCCTHPTQRLVVTSSRDTTFRLW 352
            +     D T ++ DV+T  +V   +GH   +T        R ++T+S D T R W
Sbjct: 369 MLAVVLEDFTVSVIDVDTLRVVRVFSGHSNSITDLSFSGDGRWLITASMDCTVRTW 536

 Score = 31.6 bits (70), Expect = 0.86,   Method: Compositional matrix adjust.
 Identities = 24/81 (29%), Positives = 43/81 (53%), Gaps = 1/81 (1%)
 Frame = +3

Query: 147 QLVKEYIGHRDGIWDVSVTRTQPIVLGTASADHTALLWSIETGKCLVKYAGHVGSVNSIK 206
           ++V+ + GH + I D+S +     ++ TAS D T   WS+  G+ +  +A    +V S+ 
Sbjct: 426 RVVRVFSGHSNSITDLSFSGDGRWLI-TASMDCTVRTWSLVHGRLIDCFAVE-AAVTSLT 599

Query: 207 FHPSEQ-LALTASGDQTAHIW 226
             PS+  LA +  GD   ++W
Sbjct: 600 MSPSQDFLATSHVGDVGVYLW 662
>15780
          Length = 735

 Score = 34.3 bits (77), Expect = 0.12,   Method: Compositional matrix adjust.
 Identities = 15/55 (27%), Positives = 26/55 (47%)
 Frame = -1

Query: 172 LGTASADHTALLWSIETGKCLVKYAGHVGSVNSIKFHPSEQLALTASGDQTAHIW 226
           L TA ADHT ++W I +G  +     H  +V ++ F     +  +   D +  +W
Sbjct: 729 LSTAGADHTVIVWDIASGTAVAHLTAHTDTVYALCFSRDGTVLASGGMDNSIRLW 565

 Score = 31.6 bits (70), Expect = 0.82,   Method: Compositional matrix adjust.
 Identities = 16/59 (27%), Positives = 26/59 (44%)
 Frame = -1

Query: 296 KQVVTASWDRTANLYDVETSELVHSLTGHDQELTHCCTHPTQRLVVTSSRDTTFRLWDF 354
           K + TA  D T  ++D+ +   V  LT H   +   C      ++ +   D + RLWD 
Sbjct: 735 KYLSTAGADHTVIVWDIASGTAVAHLTAHTDTVYALCFSRDGTVLASGGMDNSIRLWDL 559
>01768
          Length = 1424

 Score = 33.9 bits (76), Expect = 0.15,   Method: Compositional matrix adjust.
 Identities = 34/132 (25%), Positives = 51/132 (38%), Gaps = 4/132 (3%)
 Frame = +3

Query: 93  EGQAIDGAELSKGQLKTKASHSTSQLSQKLKTTYKASTSKIVSSFKTTTSRAICQLVKEY 152
           EG AID +  +KG L T        +SQ              SS   TT ++       Y
Sbjct: 705 EGFAIDWSPAAKGWLVTGDCTGAIYISQP-------------SSSGWTTEKS------SY 827

Query: 153 IGHRDGIWDVSVTRTQPIVLGTASADHTALLWSIE----TGKCLVKYAGHVGSVNSIKFH 208
             H D + DV  +  +  V  + S D T  +W+ +        L     H   +N I ++
Sbjct: 828 AAHTDSVEDVQWSPNEGNVFASCSVDRTLRIWNTQQKPSKANVLTVPEAHSRDINVINWN 1007

Query: 209 PSEQLALTASGD 220
           P E+  L + GD
Sbjct: 1008PIEKHLLASGGD 1043

 Score = 29.6 bits (65), Expect = 3.2,   Method: Compositional matrix adjust.
 Identities = 31/134 (23%), Positives = 64/134 (47%), Gaps = 9/134 (6%)
 Frame = +3

Query: 365 FQGHTDTVTSAVFTV--GDNVVSGSDDRTVKVWDLKNMRSPIATIRTDSAINR-INVC-- 419
           +  HTD+V    ++   G+   S S DRT+++W+ +   S    +    A +R INV   
Sbjct: 825 YAAHTDSVEDVQWSPNEGNVFASCSVDRTLRIWNTQQKPSKANVLTVPEAHSRDINVINW 1004

Query: 420 --VGQKIIALPHDNRQVRLFDMSGVRLARL-PRSSRQGHRRMVCCSAWS-EDHPICNLFT 475
             + + ++A   D+  ++++D+   R   +  ++S + H + V    W+ +D  +  L  
Sbjct: 1005NPIEKHLLASGGDDGIIKIWDLRMFRNKPVSAQASFKLHSQPVTSLEWNPQDSSV--LAA 1178

Query: 476 CGFDRQAIGWNINI 489
            G D Q   W+ ++
Sbjct: 1179SGEDDQITIWDFSV 1220
>27270
          Length = 1078

 Score = 33.5 bits (75), Expect = 0.22,   Method: Compositional matrix adjust.
 Identities = 28/104 (26%), Positives = 44/104 (42%), Gaps = 4/104 (3%)
 Frame = +2

Query: 298 VVTASWDRTANLYDVETSELVHSLT-GHDQELTHCCTHPTQRLVVTSSRDTTFRLWDFRD 356
           V   S D +  LY VET    H L  GH + +T  C     R + +SS D     W+   
Sbjct: 188 VAVGSADGSVGLYSVETHTYTHMLNKGHSKAVTDMCWRADGRTLYSSSLDGHVIGWNVN- 364

Query: 357 PSIHSVNVFQ---GHTDTVTSAVFTVGDNVVSGSDDRTVKVWDL 397
            ++H +  ++   G    V          +++   D T+K+WDL
Sbjct: 365 -TLHMIEKWKATSGRHHGVHCVCLCSSSRLLTA--DHTIKMWDL 487

 Score = 29.6 bits (65), Expect = 3.1,   Method: Compositional matrix adjust.
 Identities = 28/89 (31%), Positives = 42/89 (47%), Gaps = 16/89 (17%)
 Frame = +2

Query: 176 SADHTALLWSIETGKCLVKYAGHVGSVNSIKFHP-----SEQ-------LAL----TASG 219
           +ADHT  +W + T   L +++GH  S   IK  P     SEQ       LA      A+ 
Sbjct: 455 TADHTIKMWDLTTKNVLQEFSGH--STEVIKLLPVLKPSSEQNDIGDSNLACYVFSAAAA 628

Query: 220 DQTAHIWRYVVQLPTPQPVADTSQQISGE 248
           D+T ++WR      + Q  A TS +++ E
Sbjct: 629 DRTINVWR--CDSESSQATAVTSFELTDE 709
>16199
          Length = 694

 Score = 33.1 bits (74), Expect = 0.25,   Method: Compositional matrix adjust.
 Identities = 18/54 (33%), Positives = 28/54 (51%)
 Frame = +2

Query: 328 LTHCCTHPTQRLVVTSSRDTTFRLWDFRDPSIHSVNVFQGHTDTVTSAVFTVGD 381
           LT    HP   +  T + D+  ++WD ++ +  +V  FQGH   VTS  F+  D
Sbjct: 80  LTCAQFHPDGLIFATGTEDSVIKIWDLKERA--NVANFQGHQGPVTSISFSETD 235
>14555
          Length = 627

 Score = 32.3 bits (72), Expect = 0.40,   Method: Compositional matrix adjust.
 Identities = 11/37 (29%), Positives = 20/37 (54%)
 Frame = -2

Query: 190 KCLVKYAGHVGSVNSIKFHPSEQLALTASGDQTAHIW 226
           +C+  + GH   +N ++F+PS     T S D T  ++
Sbjct: 626 ECVQMFEGHEADINCVRFYPSGDAFATGSDDATCRLF 516

 Score = 28.5 bits (62), Expect = 6.0,   Method: Compositional matrix adjust.
 Identities = 18/63 (28%), Positives = 26/63 (41%)
 Frame = -3

Query: 304 DRTANLYDVETSELVHSLTGHDQELTHCCTHPTQRLVVTSSRDTTFRLWDFRDPSIHSVN 363
           D T N++D         L GHD  ++     P    + T S D T R+W       HS N
Sbjct: 403 DYTVNVWDALKGMRSTILYGHDNRVSCLRISPDGTSLCTGSWDYTLRIWA*ERERGHSSN 224

Query: 364 VFQ 366
           + +
Sbjct: 223 IIR 215
>31474
          Length = 403

 Score = 32.3 bits (72), Expect = 0.46,   Method: Compositional matrix adjust.
 Identities = 27/97 (27%), Positives = 41/97 (42%), Gaps = 2/97 (2%)
 Frame = -3

Query: 305 RTANLYDVETSELVHSLTGHDQELTHCCTHPTQRLVVTSSRDTTFRLWDFR-DPSIHSVN 363
           RT     + T E V  L+ HD+       +PT  L+ +   D   ++W    D  +    
Sbjct: 365 RTHAKMAMATLEEVCCLSAHDEHAWCVAWNPTGTLLASCGSDKIIKIWGKEGDNWVCKST 186

Query: 364 VFQGHTDTVTSAVFT-VGDNVVSGSDDRTVKVWDLKN 399
           +   HT TV S  ++  G+ + S S D T  VW  K 
Sbjct: 185 LTDAHTRTVRSLGWSPCGNYLSSASFDATTAVWSRKG 75
>05393
          Length = 904

 Score = 31.6 bits (70), Expect = 0.69,   Method: Compositional matrix adjust.
 Identities = 27/111 (24%), Positives = 52/111 (46%), Gaps = 7/111 (6%)
 Frame = +1

Query: 296 KQVVTASWDRTANLYDVETSELVH---SLTGHDQELTHCCTHPTQRLVVTSSRDTTFRLW 352
           + ++T S+D T  + D  ++E  H   ++ G  ++      +P Q L  T         +
Sbjct: 4   RHLLTGSFDNTVKVVDCRSAETCHKSWTVEGEVEKAVWNHHNPLQLLACTDK--GMVYCF 177

Query: 353 DFRDPSIHSVNVFQ--GHTDTVTSAVFT--VGDNVVSGSDDRTVKVWDLKN 399
           D R    H   VF    H+  VT    +  +   +++ S+D+T+KVWD+++
Sbjct: 178 DIR----HEKPVFSVGAHSSCVTGVCLSSQIPGLMITTSEDKTMKVWDIQD 318
>21921
          Length = 1341

 Score = 31.6 bits (70), Expect = 0.75,   Method: Compositional matrix adjust.
 Identities = 16/39 (41%), Positives = 24/39 (61%), Gaps = 1/39 (2%)
 Frame = -1

Query: 364 VFQGHTDTVTSAVF-TVGDNVVSGSDDRTVKVWDLKNMR 401
           V++GHT  V S      G  +VSGSDD T++ W++ + R
Sbjct: 498 VYKGHTGIVRSICPDPTGQWLVSGSDDGTIRFWEVSSGR 382
>04358
          Length = 2430

 Score = 31.2 bits (69), Expect = 0.88,   Method: Compositional matrix adjust.
 Identities = 22/60 (36%), Positives = 30/60 (50%), Gaps = 2/60 (3%)
 Frame = +1

Query: 197  GHVGSVNSIKF-HPSEQLALTASGDQTAHIWRYVVQLPTPQP-VADTSQQISGEDEIECS 254
            GH   ++SI+F H    L +TAS D T  IW        P+  V+   Q+ SGE   +CS
Sbjct: 1414 GHDDVISSIRFLHTDPGLIMTASHDHTVRIW-------DPRASVSKEVQRFSGEQNTKCS 1572

 Score = 28.1 bits (61), Expect = 8.3,   Method: Compositional matrix adjust.
 Identities = 13/31 (41%), Positives = 17/31 (54%)
 Frame = +1

Query: 154  GHRDGIWDVSVTRTQPIVLGTASADHTALLW 184
            GH D I  +    T P ++ TAS DHT  +W
Sbjct: 1414 GHDDVISSIRFLHTDPGLIMTASHDHTVRIW 1506
>16105
          Length = 960

 Score = 30.8 bits (68), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 29/118 (24%), Positives = 50/118 (42%), Gaps = 13/118 (11%)
 Frame = -2

Query: 154 GHRDGIWDVSVTRTQPIVLGTASADHTALLWSI-ETGKC------LVKYAGHVGSVNSIK 206
           GH+  + D+        V+ +AS D T  +W I ++G        +V   GH      I 
Sbjct: 581 GHKGAVLDIQWCPHNDNVIASASDDCTVKVWQIPDSGLVTNLTDPVVDLVGHQKRCCLIV 402

Query: 207 FHPSEQLALTASG-DQTAHIWRY-----VVQLPTPQPVADTSQQISGEDEIECSDKDE 258
           +HPS Q  L ++G D     W       ++++  P  +   S   +G   + C+ KD+
Sbjct: 401 WHPSAQNVLVSAGADNKILFWNVGTGEPMLEVDVPDMIYCMSFNFNGS-RLVCTCKDK 231
>13890
          Length = 630

 Score = 30.0 bits (66), Expect = 2.0,   Method: Compositional matrix adjust.
 Identities = 25/76 (32%), Positives = 34/76 (44%), Gaps = 11/76 (14%)
 Frame = +1

Query: 334 HP-TQRLVVTSSRDTTFRLWDFRDPSIHSVNVFQ-----GHTDTVTSA-----VFTVGDN 382
           HP T  LV T + D   ++WD R P +  V V       G    V  +     VF+ GD 
Sbjct: 7   HPVTPHLVATGTTDC-IQVWDVRHPEV-PVRVLTHKEQLGQVQDVMFSHDGQEVFSCGDV 180

Query: 383 VVSGSDDRTVKVWDLK 398
           V   S DR++  WD +
Sbjct: 181 VSRESSDRSIMAWDFR 228
>25400
          Length = 462

 Score = 30.0 bits (66), Expect = 2.0,   Method: Composition-based stats.
 Identities = 16/56 (28%), Positives = 27/56 (48%), Gaps = 1/56 (1%)
 Frame = +3

Query: 174 TASADHTALLWSIETGKCLVKY-AGHVGSVNSIKFHPSEQLALTASGDQTAHIWRY 228
           +  A  T L++ + TG+ + K   GH   V  + +HP     +++S D T   W Y
Sbjct: 12  SGCATGTILIYDLLTGRVVRKLDGGHRSCVRDVSWHPYTNTLISSSWDGTVGKWDY 179

 Score = 29.3 bits (64), Expect = 3.7,   Method: Composition-based stats.
 Identities = 17/53 (32%), Positives = 25/53 (47%), Gaps = 1/53 (1%)
 Frame = +3

Query: 309 LYDVETSELVHSLTG-HDQELTHCCTHPTQRLVVTSSRDTTFRLWDFRDPSIH 360
           +YD+ T  +V  L G H   +     HP    +++SS D T   WD+ D   H
Sbjct: 39  IYDLLTGRVVRKLDGGHRSCVRDVSWHPYTNTLISSSWDGTVGKWDYFDYWAH 197
>14500
          Length = 1238

 Score = 30.0 bits (66), Expect = 2.5,   Method: Compositional matrix adjust.
 Identities = 14/35 (40%), Positives = 18/35 (51%)
 Frame = +3

Query: 318 VHSLTGHDQELTHCCTHPTQRLVVTSSRDTTFRLW 352
           V  LTGH   + H    P    VV+++ D T RLW
Sbjct: 444 VAELTGHTARVLHMAMSPDGETVVSAAADETLRLW 548
>21960
          Length = 756

 Score = 29.6 bits (65), Expect = 2.6,   Method: Compositional matrix adjust.
 Identities = 14/58 (24%), Positives = 28/58 (48%), Gaps = 1/58 (1%)
 Frame = +1

Query: 296 KQVVTASWDRTANLYDVETSELVHSLTGHDQELTHCCT-HPTQRLVVTSSRDTTFRLW 352
           + +++ S D     +D  T  + + + G D  + +C   HPT  ++ TS  D   ++W
Sbjct: 403 EHIISGSDDGNIFYWDKNTEAVTNFMKGDDAGVVNCLEQHPTMPVLATSGLDHNVKIW 576
>02090
          Length = 1841

 Score = 29.6 bits (65), Expect = 3.0,   Method: Compositional matrix adjust.
 Identities = 23/94 (24%), Positives = 38/94 (40%), Gaps = 1/94 (1%)
 Frame = -3

Query: 264  DVSSDCPTVRVPLTS-LKSHQGVVIAADWLVGGKQVVTASWDRTANLYDVETSELVHSLT 322
            D+++  P ++  LTS   +   + I+ D    GK   +   D    ++D+    LV    
Sbjct: 1674 DLATPTPRIKAELTSSAPACYALAISPD----GKVCFSCCSDGNIAVWDLHNQTLVRQFQ 1507

Query: 323  GHDQELTHCCTHPTQRLVVTSSRDTTFRLWDFRD 356
            GH    +     P    + T   D T R WD R+
Sbjct: 1506 GHTDGASCIDISPDGTKLWTGGLDNTVRSWDLRE 1405
>06576
          Length = 1547

 Score = 28.1 bits (61), Expect = 8.7,   Method: Compositional matrix adjust.
 Identities = 12/31 (38%), Positives = 19/31 (61%), Gaps = 1/31 (3%)
 Frame = -2

Query: 197  GHVGSVNSIKFHPSEQLALTASGDQ-TAHIW 226
            GH   VNS+ F P+E+  + ++GD  T  +W
Sbjct: 1090 GHTDFVNSVTFSPTEEDQVXSTGDDLTCRVW 998
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|19527236|ref|NP_598781.1| transmembrane emp24 protein
transport domain containing 4 [Mus musculus]
         (227 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

03595                                                                 221   1e-60
19964                                                                  69   1e-12
38580                                                                  30   0.91 
>03595
          Length = 1492

 Score =  221 bits (562), Expect(2) = 1e-60,   Method: Compositional matrix adjust.
 Identities = 106/141 (75%), Positives = 122/141 (86%)
 Frame = +3

Query: 87  KVVLSRQYGSEGRFTFTSHTPGDHQICLHSNSTRMALFAGGKLRVHLDIQVGEHANNYPE 146
           K+V+SR Y +EGRFTFTSH+ G+H ICL+SNST  A    G+LRVHLDI VGEHA +Y +
Sbjct: 42  KIVMSRTYAAEGRFTFTSHSAGEHIICLNSNST--AWLYAGQLRVHLDISVGEHAVDYQQ 215

Query: 147 IAAKDKLTELQLRARQLLDQVEQIQKEQDYQRYREERFRLTSESTNQRVLWWSIAQTVIL 206
           + AKDKL+ELQLR RQLLDQVEQI KEQ+YQRYREERFR TSESTN RVLWWSIAQT+IL
Sbjct: 216 VQAKDKLSELQLRIRQLLDQVEQITKEQNYQRYREERFRQTSESTNHRVLWWSIAQTLIL 395

Query: 207 ILTGIWQMRHLKSFFEAKKLV 227
           +LTG WQM+HLKSFF+AKKLV
Sbjct: 396 LLTGFWQMQHLKSFFQAKKLV 458

 Score = 29.6 bits (65), Expect(2) = 1e-60,   Method: Compositional matrix adjust.
 Identities = 11/16 (68%), Positives = 14/16 (87%)
 Frame = +1

Query: 73 PGLGMHVEVKDPDGKV 88
          PG+GMHVEV+DP  K+
Sbjct: 1  PGIGMHVEVRDPSEKL 48
>19964
          Length = 901

 Score = 69.3 bits (168), Expect = 1e-12,   Method: Compositional matrix adjust.
 Identities = 41/155 (26%), Positives = 79/155 (50%), Gaps = 2/155 (1%)
 Frame = +2

Query: 75  LGMHVEVKDPDGKVVLSRQYGSEGRFTFTSHTPGDHQICLHSNSTRMALFAGGKLRVHLD 134
           L + V++  PD KV+   +  S G++TF +H  G ++ C    S +M+      +   +D
Sbjct: 65  LDIDVKIYGPDNKVIHQGERESNGKYTFAAHMDGIYKYCF---SNQMSTMTPKVVMFSMD 235

Query: 135 I--QVGEHANNYPEIAAKDKLTELQLRARQLLDQVEQIQKEQDYQRYREERFRLTSESTN 192
           +  +  +   +    A+  KL E+     QL   +   + EQ+Y   RE   R  +++TN
Sbjct: 236 VGEKPKDQDGDKDSDASHGKLEEM---VNQLSTALTGAKHEQEYMEVRERIHRAINDNTN 406

Query: 193 QRVLWWSIAQTVILILTGIWQMRHLKSFFEAKKLV 227
            RV+ W+  + ++L+   + Q+ +LK FFE +++V
Sbjct: 407 SRVVLWAFFEALVLVAMSLGQVYYLKRFFEVRRVV 511
>38580
          Length = 727

 Score = 30.0 bits (66), Expect = 0.91,   Method: Compositional matrix adjust.
 Identities = 11/27 (40%), Positives = 20/27 (74%)
 Frame = +3

Query: 198 WSIAQTVILILTGIWQMRHLKSFFEAK 224
           WS+ ++++++L GI Q+  L+SFF  K
Sbjct: 609 WSVGESILIVLIGIGQILVLRSFFTNK 689
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|50838806|ref|NP_766291.2| eukaryotic translation
initiation factor 4 gamma, 3 [Mus musculus]
         (1578 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

11597                                                                 231   1e-60
30336                                                                  64   5e-15
04759                                                                  77   6e-14
16157                                                                  65   2e-10
14839                                                                  54   6e-07
15705                                                                  33   0.72 
19285                                                                  33   1.3  
>11597
          Length = 2290

 Score =  231 bits (590), Expect = 1e-60,   Method: Compositional matrix adjust.
 Identities = 196/686 (28%), Positives = 314/686 (45%), Gaps = 54/686 (7%)
 Frame = +2

Query: 943  CRLLTTIGKDLDFEKAKPRMDQYFNQMEKIVKE-------------------RKTSSRIR 983
             +LL TIG +LD  KAK RMDQYF Q+EK+  +                    K S+R++
Sbjct: 2    TKLLDTIGGELDHPKAKTRMDQYFQQLEKMTSDLTAAQQSATGHMPKSKDPKDKLSTRVK 181

Query: 984  FMLQDVIDLRLCNWVSRR--ADQGPKTIEQIHKEAKIEEQEEQRKVQQ------------ 1029
            F + D+I+LR   WV RR  A   P T+ +IH++AK E+QE Q    Q            
Sbjct: 182  FGILDIIELRRNRWVKRRIHAQNMPTTLTEIHQKAKQEQQEAQFLSSQPRSEPQGARSSR 361

Query: 1030 --LMTKEKRRPGVQRVDEGGWNTVQGAKNSRVLDPSKFLKITKPTIDEK-IQLVPKAQLX 1086
                +  K RPG     + GWNTV   +  + +D ++ +KITK ++DE  + L    +  
Sbjct: 362  GGGASGGKGRPGQ---GDDGWNTVPARQVKQQIDAAR-MKITKTSVDETTLTLGGGNKFQ 529

Query: 1087 XXXXXXXXXXXXXXXXXXXXXXXTPL----EFDSRRALT-------SRGSMGREKSDKPI 1135
                                     L    E DSRR          SRG  GR       
Sbjct: 530  NWGRGSQGGGSRSQEQEKQGNRYNALNNLPENDSRRGFGRSPARSDSRGGAGR------- 688

Query: 1136 PAGTARPNTFLRGSSKDLLDNQSQEEQRREMLETVKQLTGGLDAERASTEA--DRSKTRE 1193
              G  R         +  +   S EE+ R +  T   L  G  +  +S  A  D S++R+
Sbjct: 689  -MGGDRDRRDRDRDYRKPVSRGSMEERERALHNTRSLLGAGAPSNPSSRNASRDNSRSRD 865

Query: 1194 LAKSEMCAVPAP-DKPALSEEEVERKSKSIIDEFLHINDFKEATQCIEELSAQGPLHVFV 1252
            +      A  +  D   L+  E++R+  +I +EF    +FK+A + I ELS      + V
Sbjct: 866  MPPPAAPAQASGIDVSQLNAGEIDRRINTIAEEFHSNQNFKDARESIAELSGLDK-SLLV 1042

Query: 1253 KVGVEFTLERSQITRDHMGHLLYQLVQSEKLSKQDFFKGFSETLELADDMAIDIPHIWLY 1312
               +E  +E++  TR  +G LL+ +V  + L   +  KG +E L+ A+D+ +DIP IW  
Sbjct: 1043 TTLLEKLVEKAGKTRRLLGQLLFDMVADKYLPTDNLIKGIAEFLQFAEDLELDIPKIWDN 1222

Query: 1313 LAELVTPMLKGGGISMRELIVEFSKPLLPVG--RAGVLLSEILHLLCRQMSHKKVGALWR 1370
            +AE+   ++    +     +    +PL+  G  +  + + +IL+      S  +V A W 
Sbjct: 1223 MAEVFASLVADNQVLPLSFLQASLQPLVDQGNKKEALFMPKILNKASDYKSKDEVQAQWA 1402

Query: 1371 EADLSWKDF-LPEGEDVHHFLLEQKLDFTESEGPCSSEALSKKELSAEELSQRLEKLIME 1429
             + L   DF + EG     +L          +GP        + +  E +  RL      
Sbjct: 1403 ASGLKLSDFGISEGHPDLQWL----------KGPA-------RNMVREGVQSRLRN---- 1519

Query: 1430 EKADDERIFDWVEANLDESQMSSPTFLRALMTAVCKAAIIADCSTFRVDTAVIKQRVPIL 1489
              A +E +F W++ N ++ +     F+R L+ AVC ++I A   + ++D A ++ R+P+L
Sbjct: 1520 -NASNEEVFRWIDGNFNKEETQGNKFVRELVAAVCASSIDA---SKKLDEAAMRNRLPVL 1687

Query: 1490 LKYLDSDTEKELQALYALQASIVKLDQPANLLRMFFDCLYDEEVISEDAFYKWESSKDPA 1549
             KY+  + E   QAL+++Q  + +L  P +L R  F+ LYDE+VISED+++ WE    P 
Sbjct: 1688 RKYM-LNQENGTQALFSIQHLLCELQHPKDLGRDLFELLYDEDVISEDSYFDWERRDGPK 1864

Query: 1550 E-QAGKGVALKSVTAFFTWLREAEEE 1574
            E  +GKG    ++  FF WLR   EE
Sbjct: 1865 EDMSGKGAVKMNLKNFFDWLRSGGEE 1942
>30336
          Length = 388

 Score = 63.5 bits (153), Expect(2) = 5e-15,   Method: Composition-based stats.
 Identities = 35/73 (47%), Positives = 43/73 (58%), Gaps = 2/73 (2%)
 Frame = -3

Query: 946  LTTIGKDLDFEKAKPRMDQYFNQMEKIVKERKTSSRIRFMLQDVIDLRLCNWVSRR--AD 1003
            + T+G  LD  KAK  M QYF ++E        + RIRFMLQDVI+LR   W  RR   +
Sbjct: 260  IRTVGPRLDTPKAKALMKQYFVRIEVFAVNEDLTPRIRFMLQDVIELRANEWKPRRVATE 81

Query: 1004 QGPKTIEQIHKEA 1016
             GPKTI  I +EA
Sbjct: 80   NGPKTITAIRQEA 42

 Score = 37.4 bits (85), Expect(2) = 5e-15,   Method: Composition-based stats.
 Identities = 19/43 (44%), Positives = 26/43 (60%), Gaps = 7/43 (16%)
 Frame = -1

Query: 910 GELFKLKMLTEAIMHDCVVKLLKNHD-------EESLECLCRL 945
           GEL KL ML E I+H C+ +LL+          EE +ECLC++
Sbjct: 388 GELGKLDMLYEGILHKCIQQLLEKKKNTPLRDMEEDMECLCQI 260
>04759
          Length = 2827

 Score = 77.0 bits (188), Expect = 6e-14,   Method: Compositional matrix adjust.
 Identities = 84/368 (22%), Positives = 155/368 (42%), Gaps = 19/368 (5%)
 Frame = +2

Query: 1210 LSEEEVERKSKSIIDEFLHINDFKEATQCIEELSAQGPLHV-FVKVGVEFTLERSQITRD 1268
            L+EEE++ K   ++ EF    D  +    I+EL     +   F+   +  ++ RS+  +D
Sbjct: 1538 LTEEELKEKLPDLLTEFFTNQDMNKTVTAIKELHMPKMMVADFLSQVLIGSVNRSEAEQD 1717

Query: 1269 HMGHLLYQLVQSEKLSKQDFFKGFSETLELADDMAIDIPHIWLYLAELVTPMLKGGGISM 1328
             +  L+  L   + ++   F + F+   +    +  + P I  ++A      L     S+
Sbjct: 1718 EVMKLVAALKMDKTITSDQFIEXFTRVADQMSALEQETPLIKSHMARFGAQALSCEVSSL 1897

Query: 1329 RELIVEFSKPLLPVGRAGVLLSEILHLLCRQMSHKK-----VGALWREADLSWKDFLPEG 1383
             EL   F        + GV     L LLC Q +H+      +  L+ +++L+ +D LPE 
Sbjct: 1898 TELAQPF--------QGGVHYP--LFLLCLQAAHRLHDKSWLVKLFNQSNLNLQDMLPEI 2047

Query: 1384 EDVHHFLLEQKLDFTESEGPCSSEALSKKELSAEELSQRLEKLIMEEKADDERIFDWVEA 1443
            +       E+ ++  E  G      L +       +   L + I  E +    IF W++ 
Sbjct: 2048 DQKK----ERMMEILEDRGLSFLFPLLR-------VQSELGRQIAAEPSAGA-IFKWIKE 2191

Query: 1444 NLDESQMSSPTFLRALMTAVCKAA-------------IIADCSTFRVDTAVIKQRVPILL 1490
             +D    ++P F+  L+  V K               +  D S    +  ++ +   +L 
Sbjct: 2192 RVDPDLFANPNFINILVAGVVKYITGESTLAENADPNVTPDKSLMDKEKELLDKLKGVLQ 2371

Query: 1491 KYLDSDTEKELQALYALQASIVKLDQPANLLRMFFDCLYDEEVISEDAFYKWESSKDPAE 1550
            K+L    + ++ ALYA+Q        P  +L  FF  LYD+E++ E+AF  W+   +  +
Sbjct: 2372 KFLHEHIDLQVSALYAVQVFCHSHHFPKGMLLRFFVNLYDQEIVEEEAFLHWKEEVN-DQ 2548

Query: 1551 QAGKGVAL 1558
              GKG AL
Sbjct: 2549 YPGKGKAL 2572
>16157
          Length = 1330

 Score = 65.1 bits (157), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 42/147 (28%), Positives = 69/147 (46%), Gaps = 13/147 (8%)
 Frame = -1

Query: 1438 FDWVEANLDESQMSSPTFLRALMTAVCKAAIIADCSTFRVDTA-------------VIKQ 1484
            F W++ ++D    ++P F+  L+T+V K           VD++             ++ +
Sbjct: 1072 FKWIKDHVDPDLFTNPKFIHILVTSVVKYITSESTLAENVDSSAAPDKAASDKEKELLDK 893

Query: 1485 RVPILLKYLDSDTEKELQALYALQASIVKLDQPANLLRMFFDCLYDEEVISEDAFYKWES 1544
               +L K+L      ++ ALYA+Q        P  +L  FF  LYD+E+I E+AF  W+ 
Sbjct: 892  LKGVLQKFLHEHLSLQVSALYAVQVFCHSHHFPKGMLLRFFVNLYDQEIIEEEAFLHWKE 713

Query: 1545 SKDPAEQAGKGVALKSVTAFFTWLREA 1571
              +  E  GKG  L  V  + TWL +A
Sbjct: 712  EVND-EFPGKGKXLFQVNQWLTWLEQA 635
>14839
          Length = 340

 Score = 53.5 bits (127), Expect = 6e-07,   Method: Composition-based stats.
 Identities = 29/72 (40%), Positives = 40/72 (55%)
 Frame = +3

Query: 1500 ELQALYALQASIVKLDQPANLLRMFFDCLYDEEVISEDAFYKWESSKDPAEQAGKGVALK 1559
            ++ ALYA+Q        P  +L  FF  LYD+E+I E+AF  W+   +  E  GKG AL 
Sbjct: 15   QVSALYAVQVFCHSHHFPKGMLLRFFVNLYDQEIIEEEAFLHWKEEVND-EFPGKGKALF 191

Query: 1560 SVTAFFTWLREA 1571
             V  + TWL +A
Sbjct: 192  QVNQWLTWLEQA 227
>15705
          Length = 2141

 Score = 33.5 bits (75), Expect = 0.72,   Method: Compositional matrix adjust.
 Identities = 28/90 (31%), Positives = 47/90 (52%), Gaps = 1/90 (1%)
 Frame = +1

Query: 1489 LLKYLDSDTEKELQALYALQASIVKLDQPANLLRMFFDCLYDEEVISEDAFYKWESS-KD 1547
            LLK+   + E +   L+ L+   V+ ++  ++L      LYD+++I E     W  +  +
Sbjct: 844  LLKHYTKNKEAQWDCLHTLEDFAVESERMLSVLGKVVQYLYDKDIIDERIIIAWHHTEAE 1023

Query: 1548 PAEQAGKGVALKSVTAFFTWLREAEEESED 1577
              E+   G   + + AF TWL EAEEES+D
Sbjct: 1024 EDEEEEHGKIRRQMQAFVTWLEEAEEESDD 1113
>19285
          Length = 396

 Score = 32.7 bits (73), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 28/112 (25%), Positives = 50/112 (44%), Gaps = 18/112 (16%)
 Frame = +1

Query: 904 GNIKFIGELF------------KLKMLTEAIMHDCVVKLLKNHDEESLECLCRLLTTIG- 950
           G   F+GELF            +L  L  A+  D V+ LL +  + S++  C+LL   G 
Sbjct: 25  GLTLFMGELFLNVTADSSGQTERLHFLPTALT-DLVLTLLSHPSDLSVKTACQLLKMAGG 201

Query: 951 --KDLDFEKAKPRMDQY---FNQMEKIVKERKTSSRIRFMLQDVIDLRLCNW 997
             +D   +K       +   F+ ++ +      S  ++ +++ V+DLR  NW
Sbjct: 202 HTEDAMCQKETHEQQNFHSIFSSLQNLQNAPHISQNMKLLMKSVLDLRQNNW 357
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|7710062|ref|NP_057904.1| membrane protein,
palmitoylated 2 (MAGUK p55 subfamily member 2) [Mus musculus]
         (552 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

13641                                                                 227   1e-60
27435                                                                 139   3e-33
35802                                                                 137   8e-33
11512                                                                 129   3e-30
29974                                                                  87   2e-17
37412                                                                  77   3e-14
29636                                                                  65   1e-10
33158                                                                  64   2e-10
11574                                                                  62   7e-10
08480                                                                  57   3e-08
00341                                                                  32   0.96 
20073                                                                  31   1.4  
01169                                                                  31   1.5  
30740                                                                  30   1.8  
17286                                                                  28   7.5  
26154                                                                  28   9.6  
>13641
          Length = 2081

 Score =  227 bits (578), Expect(2) = 1e-60,   Method: Compositional matrix adjust.
 Identities = 140/352 (39%), Positives = 199/352 (56%), Gaps = 18/352 (5%)
 Frame = +2

Query: 207 ASGSVILKILPSYQEP-HLPRQVFVKCHFDYDPARDSLSPCKEAGLRFNAGDLLQIVNQD 265
            SGS+ LK++PS + P    R++ VK  F ++   D   PCKEAGL F  GD+L IVNQ+
Sbjct: 86  TSGSLTLKLVPSRRTPGSKKREMVVKAMFSFNSKLDDNIPCKEAGLSFQQGDILHIVNQE 265

Query: 266 DANWWQAC-HVEGGS-AGLIPSQLLEEK----RKAFVKRDLELTPTSGTLCGSLSGKKKK 319
           DA WWQA  H +    AGLIPS+   E+    RK+  K    +  +      S    K++
Sbjct: 266 DAIWWQAYKHGDAKKRAGLIPSRHYHERQEVLRKSKSKEGRHMARSISPCRYSPKVPKQR 445

Query: 320 RM---MYLTTKN---AEFDRHELLIYEEVARMPPFRR--KTLVLIGAQGVGRRSLKNKLI 371
           R+   MY   +N    +FD  E+  Y+EV    P  R  + +VLIGA G+GR  LK +L 
Sbjct: 446 RLRKTMYHIVQNGALTDFDTDEIPAYDEVEHFTPKPRHFRPIVLIGAPGIGRNELKRRLK 625

Query: 372 LWDPDRYGTTVPYTSRRPKDSEREGQGYSFVSRGEMEADIRAGRYLEHGEYEGNLYGTRI 431
             +P  +   VPYT+R  K  E +G+ Y FVSR +ME  I A +++E+GE+ G+LYGT +
Sbjct: 626 ASNPMHFLEVVPYTTRTKKPFEEDGKEYHFVSREDMEESIIAQKFVEYGEHHGHLYGTSV 805

Query: 432 DSIRGVVASGKVCVLDVNPQAVKVLRTAEFVPYVVFIEAPDYETL---RAMNRAALESGV 488
           +SI+ V+A+GKVC+L  + QA+K LRT E  PYV+FI++P  E L   R   RA      
Sbjct: 806 ESIKQVIAAGKVCLLTPHTQALKFLRTYELKPYVIFIKSPTLEKLKESRMPARARATEAD 985

Query: 489 STKQLTEADLRRTVEESSRIQRGYGHYFDLSLVNSNLERTFRELQTAMEKLR 540
           S +  +  +L    E S R++  YGH FD+++VN +L     EL     K R
Sbjct: 986 SIRPFSIEELEEMAETSRRLEERYGHVFDITIVNDSLTDATTELLMVASK*R 1141

 Score = 25.0 bits (53), Expect(2) = 1e-60,   Method: Compositional matrix adjust.
 Identities = 9/13 (69%), Positives = 10/13 (76%)
 Frame = +1

Query: 538  KLRTEPQWVPVSW 550
            K+  EPQWVPV W
Sbjct: 1132 KIEKEPQWVPVGW 1170
>27435
          Length = 456

 Score =  139 bits (349), Expect = 3e-33,   Method: Compositional matrix adjust.
 Identities = 59/157 (37%), Positives = 99/157 (63%)
 Frame = +1

Query: 393 EREGQGYSFVSRGEMEADIRAGRYLEHGEYEGNLYGTRIDSIRGVVASGKVCVLDVNPQA 452
           E  G+ Y F++R   EAD+ +G+++E+GE++GNLYGT ++++R V+  G++C+L++ P++
Sbjct: 1   EHNGKDYHFITRAVFEADMLSGKFVEYGEFQGNLYGTTVEAVRQVIQQGRICILNLGPES 180

Query: 453 VKVLRTAEFVPYVVFIEAPDYETLRAMNRAALESGVSTKQLTEADLRRTVEESSRIQRGY 512
           +K LR  E  PY++FI  P  E LR +  A     +   + T+  ++  +E    ++  Y
Sbjct: 181 LKNLRETELKPYIIFISPPXMEKLRQLQMA-----LGKPRPTDDQVKEVIERGREMEEMY 345

Query: 513 GHYFDLSLVNSNLERTFRELQTAMEKLRTEPQWVPVS 549
            HYFD  LVN  L R F EL   + ++ TEPQWVP++
Sbjct: 346 SHYFDYILVNMELNRAFDELLQEINRIETEPQWVPIT 456
>35802
          Length = 571

 Score =  137 bits (346), Expect = 8e-33,   Method: Compositional matrix adjust.
 Identities = 58/159 (36%), Positives = 104/159 (65%)
 Frame = +1

Query: 393 EREGQGYSFVSRGEMEADIRAGRYLEHGEYEGNLYGTRIDSIRGVVASGKVCVLDVNPQA 452
           E  G+ Y F SR   EAD+ +G++LE+GE++ NLYGT ++++R V+  G+VC+L++ P++
Sbjct: 1   EMTGRDYHFTSRSMFEADMLSGKFLEYGEFQSNLYGTSVEAVRQVILQGRVCLLNLEPES 180

Query: 453 VKVLRTAEFVPYVVFIEAPDYETLRAMNRAALESGVSTKQLTEADLRRTVEESSRIQRGY 512
           +K+LR  +  PY  F+  P+ E LR ++ A     +   + T+  L+  +++   ++  Y
Sbjct: 181 LKILRETDLKPYTXFVCPPNMEKLRQLHIA-----MGKIRPTDDQLKTVMDKGREMEDMY 345

Query: 513 GHYFDLSLVNSNLERTFRELQTAMEKLRTEPQWVPVSWV 551
           GH+FD  LVN +++R+ +EL   + ++  EPQWVPV+W+
Sbjct: 346 GHFFDYKLVNMDVDRSVQELMAEINRIEVEPQWVPVTWM 462
>11512
          Length = 1006

 Score =  129 bits (324), Expect = 3e-30,   Method: Compositional matrix adjust.
 Identities = 58/157 (36%), Positives = 95/157 (60%), Gaps = 4/157 (2%)
 Frame = -3

Query: 399  YSFVSRGEMEADIRAGRYLEHGEYEGNLYGTRIDSIRGVVASGKVCVLDVNPQAVKVLRT 458
            Y FV+R +M+ADI AG+++EHGEY+G+LYGT  +S++ +V +G VCVL  + QA+K LRT
Sbjct: 1004 YIFVAREKMDADIEAGKFVEHGEYKGHLYGTSAESVKSIVNAGCVCVLSPHYQAIKTLRT 825

Query: 459  AEFVPYVVFIEAPDYETLRAMNRAALESGV----STKQLTEADLRRTVEESSRIQRGYGH 514
             +  P+++ I+ P+ + L++    A         + +  T+ +    ++ + RI   YGH
Sbjct: 824  XQLKPFLIHIKPPELDILKSTRTEARAKSTFDEANARSFTDEEFEDMIKSTXRIDFTYGH 645

Query: 515  YFDLSLVNSNLERTFRELQTAMEKLRTEPQWVPVSWV 551
            +FD+ +VN  L   F  L   +++L  EP W P  WV
Sbjct: 644  FFDVEIVNGELLAAFEXLVQHVQRLENEPLWAPSMWV 534
>29974
          Length = 344

 Score = 87.0 bits (214), Expect = 2e-17,   Method: Compositional matrix adjust.
 Identities = 42/104 (40%), Positives = 65/104 (62%), Gaps = 1/104 (0%)
 Frame = +1

Query: 367 KNKLILWDPDRYGTTVPYTSRRPKDSEREGQGYSFVS-RGEMEADIRAGRYLEHGEYEGN 425
            + LI   PD++G+ +P+T+R  + +E  GQ Y FVS R +ME DI+   ++E G Y  N
Sbjct: 1   NDDLISEFPDKFGSCIPHTTRERRTNEEPGQDYHFVSSREQMERDIQNHLFIEAGVYNDN 180

Query: 426 LYGTRIDSIRGVVASGKVCVLDVNPQAVKVLRTAEFVPYVVFIE 469
           LYGT + S++ V   G+ C+LDV+  A+K L+ A   P  +FI+
Sbjct: 181 LYGTSVASVKEVAEQGRHCILDVSGNAIKRLQVAGLYPIAIFIK 312
>37412
          Length = 757

 Score = 76.6 bits (187), Expect = 3e-14,   Method: Compositional matrix adjust.
 Identities = 47/141 (33%), Positives = 77/141 (54%), Gaps = 8/141 (5%)
 Frame = -1

Query: 404 RGEMEADIRAGRYLEHGEYEGNLYGTRIDSIRGVVASGK-VCVLDVNPQAVKVLRTAEFV 462
           R  ME+DI +GRYLE+G++ GNLYGTR+D++R +V SG+ VC     P   K  R     
Sbjct: 739 RLTMESDIMSGRYLEYGDFNGNLYGTRLDTVRQIVDSGRCVCWTSTLPH-*KSSRRPSSC 563

Query: 463 PYVVFIEAPDYETLRAMNRAALESGVSTKQLTEADLR-------RTVEESSRIQRGYGHY 515
           P      +P      + +   ++ G+     +  +L+        T++ES +I+R Y  Y
Sbjct: 562 P--TLCSSPRLAWKLSKSCTKMDDGLHAAAGSVVELK*NGGNFIETMKESQQIERVYASY 389

Query: 516 FDLSLVNSNLERTFRELQTAM 536
           FD  +VN + E T+R+L+ ++
Sbjct: 388 FDDIIVNDSFEDTYRQLRRSL 326
>29636
          Length = 354

 Score = 64.7 bits (156), Expect = 1e-10,   Method: Composition-based stats.
 Identities = 30/65 (46%), Positives = 41/65 (63%), Gaps = 4/65 (6%)
 Frame = +1

Query: 234 FDYDPARDSLSPCKEAGLRFNAGDLLQIVNQDDANWWQACHVEGGS----AGLIPSQLLE 289
           F+YDP  D   PC+E G+ F  GD+L  +   D+NWWQA H EG      AGLIPS+  +
Sbjct: 88  FNYDPEDDPYIPCRELGISFLKGDILHAIQLSDSNWWQA-HREGEDAHMLAGLIPSKAFQ 264

Query: 290 EKRKA 294
           E+R++
Sbjct: 265 EQRES 279
>33158
          Length = 1075

 Score = 63.5 bits (153), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 53/190 (27%), Positives = 96/190 (50%), Gaps = 14/190 (7%)
 Frame = +2

Query: 10  SAMQQVLDNLGSLPN----ATGAAELDLIFLRGIMESPIVRSLAKAHERLEETKLEA--- 62
           S +Q +   L S  N    +TG  E+   FL+ +  +P+ +     H+++ +    +   
Sbjct: 521 STLQHIRTRLSSADNTNDSSTGQQEVH--FLKQLFHNPLFQQTVDMHQKMVDVTSRSPLP 694

Query: 63  --VRDNNLELVQEILRDLAELAEQSSTAA--ELARILQEPHFQSLLETHDSVASKTYETP 118
             +  ++ EL  ++    +E+    S A   EL+ +L +P  ++LL+ HD VA +  +T 
Sbjct: 695 RPLGSDSQELACDVKSYGSEMGGSXSEAVVEELSMLLDKPALKNLLKAHDEVADQ--QTH 868

Query: 119 PPSPGLDPTFSNQPVPP---DAVRMVGIRKTAGEHLGVTFRVEGGELVIARILHGGMVAQ 175
           P     +    + P+     ++V+++ + KT  EHLG T + EG  ++IARI+ GG   +
Sbjct: 869 PILHVSESDLIDYPLTEYGEESVKIIHLEKT-NEHLGATVKNEGDSVLIARIVKGGAAEK 1045

Query: 176 QGLLHVGDII 185
            GLLH GD I
Sbjct: 1046SGLLHEGDEI 1075
>11574
          Length = 1255

 Score = 62.0 bits (149), Expect = 7e-10,   Method: Compositional matrix adjust.
 Identities = 23/45 (51%), Positives = 35/45 (77%)
 Frame = +2

Query: 508 IQRGYGHYFDLSLVNSNLERTFRELQTAMEKLRTEPQWVPVSWVY 552
           +++ YGH+FD  +VN++++ T R L+ A+E + T PQWVPVSWVY
Sbjct: 14  VEKAYGHFFDRQIVNNDIDETIRTLEKAIEDVCTLPQWVPVSWVY 148
>08480
          Length = 698

 Score = 56.6 bits (135), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 31/87 (35%), Positives = 49/87 (56%), Gaps = 6/87 (6%)
 Frame = -1

Query: 226 RQVFVKCHFDYDPARDSLSPCKEAGLRFNAGDLLQIVNQDDANWWQACHV------EGGS 279
           R +FV+  FDY+P++DS  P +  GL F+ GD+L + N  D  WWQA  +      EG  
Sbjct: 458 RTMFVRALFDYEPSKDSGLPSR--GLWFHYGDILHVTNASDDEWWQAKRILPDGKEEG-- 291

Query: 280 AGLIPSQLLEEKRKAFVKRDLELTPTS 306
            G+IPS+   E+++    R+++    S
Sbjct: 290 MGIIPSKRRVERKERARLRNVKFGKNS 210
>00341
          Length = 1915

 Score = 31.6 bits (70), Expect = 0.96,   Method: Compositional matrix adjust.
 Identities = 18/57 (31%), Positives = 30/57 (52%), Gaps = 1/57 (1%)
 Frame = -1

Query: 234  FDYDPARDSLSPCKEAGLRFNAGDLLQIVNQDDANWWQACHVE-GGSAGLIPSQLLE 289
            +DYDP + S    +   L F+AGD+L +  +   + +   H E  G  GL+P+  +E
Sbjct: 1837 YDYDPEKQSPGDYRACELAFHAGDILLVYGEARQDGFY--HGERNGQRGLVPACFVE 1673
>20073
          Length = 582

 Score = 30.8 bits (68), Expect = 1.4,   Method: Compositional matrix adjust.
 Identities = 26/70 (37%), Positives = 36/70 (51%), Gaps = 6/70 (8%)
 Frame = +3

Query: 152 GVTFRVEGGE-----LVIARILHGGMVAQQGLLHVGDIIKEVNGQPV-GSDPRALQELLR 205
           G+ F V GG+     + I+RI+ GG+  +   L  GD +  VNG  V G       ELL+
Sbjct: 3   GLGFNVMGGKEQSSPIYISRIIPGGVADRLNCLKRGDQLLSVNGVSVEGEYHEKAVELLK 182

Query: 206 SASGSVILKI 215
            A GSV L +
Sbjct: 183 LAQGSVRLVV 212
>01169
          Length = 1267

 Score = 30.8 bits (68), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 27/88 (30%), Positives = 38/88 (43%), Gaps = 8/88 (9%)
 Frame = +3

Query: 230 VKCHFDYDPARDSLSPC--KEAGLRFNAGDLLQIVNQDDANWWQACHVEGGSAGL---IP 284
           ++ H D +P  + L PC     G  F   DL+++ +   AN  QA    G  A L   IP
Sbjct: 417 IRGHLDNNPGLEKLLPCIKNNVGFVFTREDLVEVRDLLLANKVQAPARTGALAPLDVKIP 596

Query: 285 SQ---LLEEKRKAFVKRDLELTPTSGTL 309
           +Q   L  EK   F    +    T GT+
Sbjct: 597 AQATPLGPEKTSFFQALQIPTKITKGTI 680
>30740
          Length = 488

 Score = 30.4 bits (67), Expect = 1.8,   Method: Compositional matrix adjust.
 Identities = 9/22 (40%), Positives = 17/22 (77%)
 Frame = +2

Query: 251 LRFNAGDLLQIVNQDDANWWQA 272
           L F+ GD+L+++++D+  WW A
Sbjct: 233 LPFSKGDILELISKDEEEWWTA 298
>17286
          Length = 489

 Score = 28.5 bits (62), Expect = 7.5,   Method: Composition-based stats.
 Identities = 14/46 (30%), Positives = 24/46 (52%), Gaps = 1/46 (2%)
 Frame = +3

Query: 245 PCKEAGLRFNAGDLLQIVNQDDANWWQ-ACHVEGGSAGLIPSQLLE 289
           P  +  L F  GD++ +++Q D NW++ + H   G  G  P   +E
Sbjct: 54  PESDGELGFQEGDMITLISQVDENWFEGSVH---GKVGYFPINYVE 182
>26154
          Length = 446

 Score = 28.1 bits (61), Expect = 9.6,   Method: Composition-based stats.
 Identities = 17/55 (30%), Positives = 28/55 (50%), Gaps = 5/55 (9%)
 Frame = -3

Query: 148 GEHLGVTFRVEGGE-----LVIARILHGGMVAQQGLLHVGDIIKEVNGQPVGSDP 197
           G  LG+T  + G E     +VI+ +  GG+  + G +HVGD +  +N     + P
Sbjct: 204 GGPLGIT--ISGTEDPLDNIVISELTAGGLAQKTGAMHVGDRLLGINESTTKTSP 46
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31981592|ref|NP_598599.2| EH-domain containing 4 [Mus
musculus]
         (541 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

28292                                                                 229   2e-60
19303                                                                 134   4e-49
01130                                                                  65   7e-11
20290                                                                  31   1.5  
18248                                                                  29   4.5  
14594                                                                  28   7.3  
>28292
          Length = 1324

 Score =  229 bits (584), Expect = 2e-60,   Method: Compositional matrix adjust.
 Identities = 122/286 (42%), Positives = 167/286 (58%), Gaps = 2/286 (0%)
 Frame = -3

Query: 28   LRSLYQRKVLPLEEAYRFHEFHSPALEDADFENKPMILLVGQYSTGKTTFIRYLL--EQD 85
            L  +Y+  + PLE+AYRF + +  A+ + +   KPMIL +G +STGK+T I Y+L  EQ 
Sbjct: 1205 LLEIYKENIQPLEQAYRFADLNRDAISEGEMLAKPMILFLGPWSTGKSTMINYILKNEQA 1026

Query: 86   FPGMRIGPEPTTDSFIAVMYGETEGSTPGNALVVDPKKPFRKLSRFGNAFLNRFMCSQLP 145
               +  G EPTT  F  V YG T     G  LV D  K +  L +FG  FL RF   +LP
Sbjct: 1025 NWKLHTGAEPTTSDFTMVTYGITARMVKGIQLVSDKTKHYTPLQKFGLNFLERFQGMELP 846

Query: 146  NQVLKSISIIDSPGILSGEKQRISRGYDFCQVLQWFAERVDRIILLFDAHKLDISDEFSE 205
              +LK ++++D+PGI+  +KQ+  RGY F  V QWF +R   I L+FD  KLDI  E   
Sbjct: 845  APLLKQVTLVDTPGIIENKKQQ-ERGYPFNDVCQWFIDRAQLIFLVFDPSKLDIGSELEM 669

Query: 206  AIKAFRGQDDKIRVVLNKADQVDTQQLMRVYGALMWSLGKVINTPEVLRVYIGSFWAQPL 265
              +  +G + K+R++LNKAD V TQ+LMRVYGAL WSL  +IN  E  RVY+GS W+Q  
Sbjct: 668  LFRQLKGHEAKLRLILNKADTVTTQELMRVYGALFWSLAPLINLVEPPRVYVGSMWSQSY 489

Query: 266  QNTDNRRLFEAEAQDLFRDIQSLPQKAAVRKLNDLIKRARLAKVHA 311
            Q T    LFE E   L  D+Q + +     K+    + A L ++HA
Sbjct: 488  QPTTMHTLFEEEETSLSMDLQQVIRYQLEYKIAATRRHAFLVRLHA 351
>19303
          Length = 676

 Score =  134 bits (336), Expect(2) = 4e-49,   Method: Compositional matrix adjust.
 Identities = 63/93 (67%), Positives = 76/93 (81%)
 Frame = -1

Query: 442 WVVAKDKPVYDELFYTLSPINGKISGVNAKKEMVTSKLPNSVLGKIWKLADCDCDGMLDE 501
           WVV+++K  YD+ F  L+PINGK+SG  AK EMV SKLPNSVL K+WKLAD D DGMLD 
Sbjct: 415 WVVSREKYEYDDSFSKLNPINGKVSGAAAKSEMVKSKLPNSVLSKVWKLADVDKDGMLDA 236

Query: 502 EEFALAKHLIKIKLDGYELPNSLPPHLVPPSHR 534
           +E+ALA HLIKIKL+G++LP+ LP HLVPPS R
Sbjct: 235 DEWALANHLIKIKLEGHDLPSDLPSHLVPPSKR 137

 Score = 79.7 bits (195), Expect(2) = 4e-49,   Method: Compositional matrix adjust.
 Identities = 40/71 (56%), Positives = 50/71 (70%), Gaps = 2/71 (2%)
 Frame = -2

Query: 358 EVKAMQEQLENYDFTKFHSLKPKLIEAVDNMLTNKISSLMGLI--SQEEMNMPTQMVQGG 415
           E+K MQEQL  +DFTKFH++KPKL+E VDNML N I+ LM +I    E+ +     VQGG
Sbjct: 675 ELKRMQEQLAFHDFTKFHAIKPKLLETVDNMLANDIARLMQMIPLEDEDQSNGQAAVQGG 496

Query: 416 AFDGTTEGPFN 426
           AF+G TE PF 
Sbjct: 495 AFEGYTESPFG 463
>01130
          Length = 1032

 Score = 65.1 bits (157), Expect = 7e-11,   Method: Compositional matrix adjust.
 Identities = 35/92 (38%), Positives = 50/92 (54%), Gaps = 2/92 (2%)
 Frame = +3

Query: 442 WVVAKD--KPVYDELFYTLSPINGKISGVNAKKEMVTSKLPNSVLGKIWKLADCDCDGML 499
           W V  D  + +Y+ LFY+  P++G I G   +   + S L   VL +IW LAD   D +L
Sbjct: 210 WPVVSDEERQLYELLFYSQGPVDGYILGEGVRDLFLKSGLSLRVLSQIWNLADVSNDNVL 389

Query: 500 DEEEFALAKHLIKIKLDGYELPNSLPPHLVPP 531
           +  EF+L  HLI+    G + P +LP  L PP
Sbjct: 390 NVHEFSLVMHLIRGLHKGLKAPPTLPRKLTPP 485

 Score = 43.5 bits (101), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 30/100 (30%), Positives = 46/100 (46%), Gaps = 8/100 (8%)
 Frame = +3

Query: 443 VVAKDKPVYDELFYTLSPINGK--ISGVNAKKEMVTSKLPNSVLGKIWKLADCDCDGMLD 500
           +   ++  Y +LF  L  + GK  + G   +     S+L + VL  +W L+D   DG LD
Sbjct: 513 ITPPEREAYIKLFRALD-VQGKGFLDGDCCRHVFEASELTSDVLSDVWNLSDVTRDGKLD 689

Query: 501 EEEFALAKHLIKIKLDGYELP------NSLPPHLVPPSHR 534
            +EF +A HL++    G  L         LP  + P S R
Sbjct: 690 VDEFCVACHLLRFVKAGNSLSGPVDVFTELPDKVAPQSLR 809
>20290
          Length = 1550

 Score = 30.8 bits (68), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 16/51 (31%), Positives = 27/51 (52%), Gaps = 7/51 (13%)
 Frame = +1

Query: 52  ALEDADFENKPMILLVGQYSTGKTTFIRYLL-------EQDFPGMRIGPEP 95
            ++   F +  +++L+G+  TGKTTFIR L        E + P + I  +P
Sbjct: 751 TVQQGHFSDSEILVLLGENGTGKTTFIRMLAGNLQPDGEVELPMLNISYKP 903
>18248
          Length = 466

 Score = 29.3 bits (64), Expect = 4.5,   Method: Compositional matrix adjust.
 Identities = 11/30 (36%), Positives = 20/30 (66%)
 Frame = +3

Query: 52  ALEDADFENKPMILLVGQYSTGKTTFIRYL 81
            +   +F +  +I+++G+  TGKTTFI+ L
Sbjct: 72  TVHPGEFTDSEIIVMLGENGTGKTTFIKML 161
>14594
          Length = 1014

 Score = 28.5 bits (62), Expect = 7.3,   Method: Compositional matrix adjust.
 Identities = 17/46 (36%), Positives = 24/46 (52%), Gaps = 2/46 (4%)
 Frame = +3

Query: 462 NGKISGVNAKKEMVT--SKLPNSVLGKIWKLADCDCDGMLDEEEFA 505
           NG IS    +  M     KL +  + ++ K AD D DGM++ EEF 
Sbjct: 702 NGYISAAELRHVMTNLGEKLTDEEVDEMIKEADLDGDGMVNYEEFV 839
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|124244073|ref|NP_700473.2| nephrocystin 4 [Mus
musculus]
         (1425 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

07008                                                                 230   3e-60
14415                                                                  45   2e-04
14117                                                                  32   1.4  
>07008
          Length = 1270

 Score =  230 bits (586), Expect = 3e-60,   Method: Compositional matrix adjust.
 Identities = 121/273 (44%), Positives = 171/273 (62%), Gaps = 5/273 (1%)
 Frame = -2

Query: 565 EHLQELPFTPLHAPIVVGAQTRSSRSQLSRAAMVLLQSSGFPEILDASQQPVEAVNPIDP 624
             +++LPFT +H P+V+          LSRAA   L S+GFP +LD +  P E ++P  P
Sbjct: 831 SEMRDLPFTQVHQPLVLRPPXAYGGQSLSRAAYARLYSAGFPPVLDRNGDPPEVMDPSLP 652

Query: 625 VRFNPQKEESDCLRGNEIVLQFLAFS-----RAAQDCPGTPWPQTVYFTFQFYRFPPETT 679
           +  N  +E +D L+ NEI+ QFLAFS     R++Q  PG      V+FTFQFYR+P  TT
Sbjct: 651 MSVNLARENADSLQANEIIFQFLAFSKLLPGRSSQASPGC-----VFFTFQFYRYPQVTT 487

Query: 680 PRLQLVKLDGTGKSGSGSLSHILVPINKDGSFDAGSPGLQLRYMVDPGFLKPGEQRWFAH 739
            R+ L K DG   +   +L  IL  +++DG+   G+PG+++RY++DP ++KPGE   F  
Sbjct: 486 ERMLLCKPDGQLSNNQDNLPFILQKLSRDGTVLKGAPGIEVRYLLDPTYMKPGEVALFLQ 307

Query: 740 YLAAQTLQVDVWDGDSLLLIGSAGVQMKHLLRQGRPAVQVSHELEVVATEYEQEMMAVSG 799
           +LA QTL VDVWDGDSLLLIGS  V MK+L R G+ AVQ + EL+V +T+   +   ++G
Sbjct: 306 HLARQTLHVDVWDGDSLLLIGSCSVDMKYLCRGGQEAVQATFELDVSSTDQSDDGSGLTG 127

Query: 800 DVAGFGSVKPIGVHTVVKGRLHLTLANVGHACE 832
           D+   GSV+P+       G+LHL +ANVGH  E
Sbjct: 126 DIQRGGSVRPVSTQHRSCGKLHLRIANVGHTVE 28
>14415
          Length = 427

 Score = 45.1 bits (105), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 27/89 (30%), Positives = 39/89 (43%)
 Frame = +2

Query: 334 GNQALVLRSHLRLPEMVSHPAFAIVFQLEYVFNXXXXXXXXXXXXXXISSVACMHMVRWA 393
           GN  LVL+S ++L ++V  P FA+VF L YV +                +      VRW 
Sbjct: 164 GN-CLVLKSRIQLNDLVQDPMFAVVFTLHYVISESLSDKDRKMSLSLARAHTRTVSVRWV 340

Query: 394 VWNPDLEVGPGKVTLPLQGGVQQNPSRCL 422
            WNP +      +T  L G +   P + L
Sbjct: 341 AWNPFMHASTTDITTALTGVLLVPPVKXL 427
>14117
          Length = 1117

 Score = 32.3 bits (72), Expect = 1.4,   Method: Composition-based stats.
 Identities = 18/54 (33%), Positives = 26/54 (48%)
 Frame = -1

Query: 1320 VCLSCRQPLISKAFEITMAAGDEKGTNKRITYTNPYPSRRTYRLHSDRPELLRF 1373
            +C+ CR  L+     I M A   +    +   TN +P+RR + LHS   E  RF
Sbjct: 295  LCVVCRLWLVF*GVNINMQANQNRHLFLKWQITNSFPTRRLFPLHSS--EYWRF 140
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|149261894|ref|XP_126172.6| PREDICTED: la related
protein [Mus musculus]
         (1339 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

08101                                                                 230   3e-60
32379                                                                  64   4e-10
13157                                                                  37   0.048
19586                                                                  35   0.16 
18562                                                                  33   0.91 
00659                                                                  32   1.6  
23917                                                                  32   1.9  
15724                                                                  32   2.0  
22170                                                                  31   3.6  
>08101
          Length = 957

 Score =  230 bits (586), Expect = 3e-60,   Method: Compositional matrix adjust.
 Identities = 112/187 (59%), Positives = 134/187 (71%)
 Frame = +3

Query: 1090 ASISSSPSEGTPAVGSYGCTPQSLPKFQHPSHELLKENGFTQHVYHKYRRRCLNERKRLG 1149
            +S+S     G     SYG TPQ  P          K+   +         +CL ERKR G
Sbjct: 24   SSLSLCQPFGKHVSASYGTTPQPFPNSSTLHINC*KKTILSGMCTINTTPKCLKERKRQG 203

Query: 1150 IGQSQEMNTLFRFWSFFLRDHFNKKMYEEFKQLALEDAKEGYRYGLECLFRYYSYGLEKK 1209
             GQSQEMNTLFRFWSFFLR H+NKKM+ EFK LA+EDAK GYRYGLECLFR++SYGLE++
Sbjct: 204  AGQSQEMNTLFRFWSFFLRQHYNKKMFLEFKVLAVEDAKAGYRYGLECLFRFFSYGLERR 383

Query: 1210 FRLDIFKDFQEETVKDYEAGQLYGLEKFWAFLKYSKAKNLDIDPKLQEYLGKFRRLEDFR 1269
            FR D+F DFQEET++DYE+ QLYGLEKFWAFLKYS+ K + I+PKLQ+ L  ++RLEDFR
Sbjct: 384  FRPDVFNDFQEETLRDYESNQLYGLEKFWAFLKYSR-KRVQINPKLQQALSHYKRLEDFR 560

Query: 1270 VDPPMGE 1276
            VDPP  E
Sbjct: 561  VDPPEAE 581
>32379
          Length = 581

 Score = 63.9 bits (154), Expect = 4e-10,   Method: Compositional matrix adjust.
 Identities = 31/74 (41%), Positives = 47/74 (63%)
 Frame = +3

Query: 626 TYYFDNVSSNEIYSMDQELLKDYIKRQIEYYFSVDNLERDFFLRRKMDADGFLPITLIAS 685
           T YF  V        D+E  +  +  Q+EYY S DNL +DFFLRR+M  +G++P+ LIA+
Sbjct: 183 TVYFQTVD-------DEETKRQCLITQVEYYLSEDNLSKDFFLRRRMKPEGWVPMNLIAT 341

Query: 686 FHRVQALTTDISLI 699
           F+R+  L+ ++ LI
Sbjct: 342 FNRMINLSRNMGLI 383
>13157
          Length = 552

 Score = 37.0 bits (84), Expect = 0.048,   Method: Composition-based stats.
 Identities = 18/52 (34%), Positives = 34/52 (65%), Gaps = 1/52 (1%)
 Frame = +1

Query: 645 LKDYIKRQIEYYFSVDNLERDFFLRRKM-DADGFLPITLIASFHRVQALTTD 695
           ++  + RQ+EYYF   NL RD FL+ K  + DG++ +  + +F+R++ ++ D
Sbjct: 379 MEKKVIRQVEYYFGDVNLPRDKFLQEKTREDDGWVSMDTMLNFNRLKQISDD 534
>19586
          Length = 989

 Score = 35.4 bits (80), Expect = 0.16,   Method: Compositional matrix adjust.
 Identities = 17/49 (34%), Positives = 29/49 (59%), Gaps = 6/49 (12%)
 Frame = +1

Query: 664 RDFFLRR------KMDADGFLPITLIASFHRVQALTTDISLIFAALKDS 706
           R +F RR      +   DGF+ + LIASF ++++LT D+ ++   L+ S
Sbjct: 424 RQYFERRVSLKHVRRTKDGFVSLKLIASFKKMKSLTKDVRVVARCLRQS 570

 Score = 31.6 bits (70), Expect = 2.0,   Method: Composition-based stats.
 Identities = 17/41 (41%), Positives = 27/41 (65%)
 Frame = +2

Query: 634 SNEIYSMDQELLKDYIKRQIEYYFSVDNLERDFFLRRKMDA 674
           S++I   D+EL ++ I +Q+E+YFS  N+ +D FL    DA
Sbjct: 350 SDDIPEPDEEL-RNKIIKQVEFYFSDANILKDVFL*NMCDA 469
>18562
          Length = 414

 Score = 32.7 bits (73), Expect = 0.91,   Method: Compositional matrix adjust.
 Identities = 11/21 (52%), Positives = 19/21 (90%)
 Frame = -1

Query: 643 ELLKDYIKRQIEYYFSVDNLE 663
           EL+++ +++Q+EYYFS +NLE
Sbjct: 63  ELIREKLQKQLEYYFSRENLE 1
>00659
          Length = 1939

 Score = 32.0 bits (71), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 22/68 (32%), Positives = 31/68 (45%), Gaps = 1/68 (1%)
 Frame = -3

Query: 736  SQTDFSQLLNCPEFVPRQHYQKETESAPGSPRAVTPVPTKTEEVSNL-KTLPKGLSASLP 794
            S+T  S  ++CP   P    +  T S PG      P+ T  EE  N+ +    GL  S  
Sbjct: 1496 SRTRRSWCMSCPPTQPNSWRRTWTRSTPGFCSGAPPMDTLLEETENVCEMCVCGLQLSGT 1317

Query: 795  DLDSESWI 802
            D+D  +WI
Sbjct: 1316 DVDIHAWI 1293
>23917
          Length = 783

 Score = 32.0 bits (71), Expect = 1.9,   Method: Compositional matrix adjust.
 Identities = 28/80 (35%), Positives = 36/80 (45%), Gaps = 7/80 (8%)
 Frame = +1

Query: 1267 DFRVDPPMGEEGNHKRHPVVAGGSGEG-----RKRCPSQSSS--RPATGISQPPTTPTGQ 1319
             F V  P+ +EG  + +   A  S E      R  CPS  SS  RPAT I +P T     
Sbjct: 538  SFTVS*PITKEGTERPNQTPAPPSAEMSDPWPRAHCPSPISSLPRPATLIYRPTTVKCHD 717

Query: 1320 ATREDAKWTSQHSDTLTLRK 1339
            A+   + W    S T+T RK
Sbjct: 718  ASLAASSW---FSSTITYRK 768
>15724
          Length = 390

 Score = 31.6 bits (70), Expect = 2.0,   Method: Compositional matrix adjust.
 Identities = 17/35 (48%), Positives = 21/35 (60%)
 Frame = +3

Query: 1086 RPRTASISSSPSEGTPAVGSYGCTPQSLPKFQHPS 1120
            R  ++ +S SPSE      SYG TPQ  P F+HPS
Sbjct: 288  RHNSSCLSVSPSESM-LSASYGTTPQPFPNFEHPS 389
>22170
          Length = 495

 Score = 30.8 bits (68), Expect = 3.6,   Method: Compositional matrix adjust.
 Identities = 14/33 (42%), Positives = 21/33 (63%)
 Frame = -1

Query: 466 DESGEEKNGDEDCQRGGQKKKGSKHKWVPLQID 498
           D + E K   +D Q+  + KKGS+ +WVPL I+
Sbjct: 147 DSAKENKENADDSQQTPKAKKGSRQRWVPLDIE 49
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31542602|ref|NP_034615.2| ELAV (embryonic lethal,
abnormal vision, Drosophila)-like 1 (Hu antigen R) [Mus musculus]
         (326 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

25691                                                                 196   3e-60
02343                                                                 108   4e-24
11687                                                                  87   1e-17
17775                                                                  86   2e-17
03744                                                                  69   2e-12
20488                                                                  67   1e-11
11019                                                                  66   2e-11
03406                                                                  63   2e-10
19868                                                                  62   4e-10
03000                                                                  61   6e-10
17681                                                                  60   9e-10
08958                                                                  60   1e-09
13457                                                                  59   3e-09
12350                                                                  58   5e-09
14637                                                                  58   6e-09
14258                                                                  56   3e-08
01278                                                                  54   9e-08
00029                                                                  52   3e-07
26197                                                                  40   3e-07
30672                                                                  52   4e-07
16427                                                                  51   5e-07
00302                                                                  50   1e-06
13822                                                                  49   3e-06
00556                                                                  49   3e-06
15371                                                                  48   6e-06
31938                                                                  46   2e-05
31618                                                                  46   2e-05
12506                                                                  45   3e-05
31310                                                                  45   6e-05
32733                                                                  44   6e-05
02415                                                                  43   1e-04
00738                                                                  43   2e-04
02140                                                                  43   2e-04
23322                                                                  42   3e-04
03200                                                                  42   3e-04
32386                                                                  42   3e-04
33516                                                                  42   3e-04
24983                                                                  41   6e-04
01065                                                                  40   0.001
09968                                                                  40   0.002
25632                                                                  39   0.004
28652                                                                  39   0.004
31265                                                                  38   0.005
04988                                                                  38   0.007
23720                                                                  38   0.007
28605                                                                  37   0.010
24794                                                                  36   0.022
15503                                                                  35   0.036
19733                                                                  35   0.049
39789                                                                  35   0.058
05273                                                                  34   0.074
12096                                                                  34   0.094
03856                                                                  33   0.19 
11126                                                                  33   0.20 
33504                                                                  32   0.27 
25950                                                                  32   0.32 
25746                                                                  32   0.52 
00781                                                                  31   0.54 
29364                                                                  31   0.66 
11579                                                                  31   0.76 
28372                                                                  30   0.98 
02077                                                                  29   2.1  
19556                                                                  29   2.2  
09947                                                                  29   2.5  
17175                                                                  28   4.6  
32930                                                                  28   5.4  
05987                                                                  27   9.8  
>25691
          Length = 768

 Score =  196 bits (499), Expect(2) = 3e-60,   Method: Compositional matrix adjust.
 Identities = 95/144 (65%), Positives = 113/144 (78%)
 Frame = -2

Query: 48  SAKLIRDKVAGHSLGYGFVNYVTAKDAERAISTLNGLRLQSKTIKVSYARPSSEVIKDAN 107
           + KLIRDK  G SLGYGFVNY   +DA++AI TLNGLRLQ+KTIKVS ARPS E IK AN
Sbjct: 434 TCKLIRDKPTGQSLGYGFVNYKRQEDADKAIHTLNGLRLQNKTIKVSLARPSCESIKGAN 255

Query: 108 LYISGLPRTMTQKDVEDMFSRFGRIINSRVLVDQTTGLSRGVAFIRFDKRSEAEEAITSF 167
           LYISGLP+++TQ D+E++F+  G II SR+L DQTTGLS+GV FIRFD+R EAE AI   
Sbjct: 254 LYISGLPKSLTQLDLENLFTDCGNIITSRILYDQTTGLSKGVGFIRFDQRIEAERAIQKL 75

Query: 168 NGHKPPGSSEPITVKFAANPNQNK 191
           N H P G  +PITVKFA +P+ NK
Sbjct: 74  NNHIPDGCIDPITVKFANSPSSNK 3

 Score = 53.5 bits (127), Expect(2) = 3e-60,   Method: Compositional matrix adjust.
 Identities = 23/33 (69%), Positives = 29/33 (87%)
 Frame = -1

Query: 15  DDIGRTNLIVNYLPQNMTQEELRSLFSSIGEVE 47
           D   +TNLIVNYLPQ M+Q+E+RSLF+SIGE+E
Sbjct: 534 DGTSKTNLIVNYLPQTMSQDEIRSLFASIGELE 436

 Score = 52.4 bits (124), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 25/74 (33%), Positives = 45/74 (60%)
 Frame = -2

Query: 9   MAEDCRDDIGRTNLIVNYLPQNMTQEELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNY 68
           +A    + I   NL ++ LP+++TQ +L +LF+  G + +++++ D+  G S G GF+ +
Sbjct: 293 LARPSCESIKGANLYISGLPKSLTQLDLENLFTDCGNIITSRILYDQTTGLSKGVGFIRF 114

Query: 69  VTAKDAERAISTLN 82
               +AERAI  LN
Sbjct: 113 DQRIEAERAIQKLN 72

 Score = 42.4 bits (98), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 21/47 (44%), Positives = 29/47 (61%)
 Frame = -2

Query: 273 VKVIRDFNTNKCKGFGFVTMTNYEEAAMAIASLNGYRLGDKILQVSF 319
            K+IRD  T +  G+GFV     E+A  AI +LNG RL +K ++VS 
Sbjct: 431 CKLIRDKPTGQSLGYGFVNYKRQEDADKAIHTLNGLRLQNKTIKVSL 291
>02343
          Length = 1715

 Score =  108 bits (269), Expect = 4e-24,   Method: Compositional matrix adjust.
 Identities = 61/178 (34%), Positives = 95/178 (53%)
 Frame = -2

Query: 15   DDIGRTNLIVNYLPQNMTQEELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDA 74
            D + +TNL +  L  N T ++L +L    G + S K I D+      GYGFV++     A
Sbjct: 1279 DPLSKTNLYIRGLSPNTTDKDLVNLCQHFGTITSTKAIIDQTTNKCKGYGFVDFDAPGAA 1100

Query: 75   ERAISTLNGLRLQSKTIKVSYARPSSEVIKDANLYISGLPRTMTQKDVEDMFSRFGRIIN 134
            ERA+  L    +Q++  K     P+       NLYI+ LP   T+K +E +F  +G +I+
Sbjct: 1099 ERAVQALQAQGIQAQMAKQQEQDPT-------NLYIANLPLHFTEKHLEGLFKDYGTVIS 941

Query: 135  SRVLVDQTTGLSRGVAFIRFDKRSEAEEAITSFNGHKPPGSSEPITVKFAANPNQNKN 192
            +R+L  +  G+SR V F R + R + +  I +FN     G SEP+ VKFA + N+ K+
Sbjct: 940  TRIL-RKPDGISRCVGFARMESRDKCDTVINTFNNKMISGCSEPLLVKFADSGNKKKS 770

 Score = 40.8 bits (94), Expect = 8e-04,   Method: Compositional matrix adjust.
 Identities = 23/70 (32%), Positives = 34/70 (48%)
 Frame = -2

Query: 238  GNASSGWCIFIYNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYEE 297
            G+  S   ++I  L  +  +  L  +   FG +T+ K I D  TNKCKG+GFV       
Sbjct: 1282 GDPLSKTNLYIRGLSPNTTDKDLVNLCQHFGTITSTKAIIDQTTNKCKGYGFVDFDAPGA 1103

Query: 298  AAMAIASLNG 307
            A  A+ +L  
Sbjct: 1102 AERAVQALQA 1073
>11687
          Length = 676

 Score = 87.0 bits (214), Expect = 1e-17,   Method: Compositional matrix adjust.
 Identities = 55/177 (31%), Positives = 87/177 (49%), Gaps = 8/177 (4%)
 Frame = +3

Query: 16  DIGRTNLIVNYLPQNMTQEELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAK--- 72
           D     + V  +P+NM + ELR +F   G V S  ++RDK  G S G  FV + T K   
Sbjct: 138 DADSIKMFVGQIPRNMDENELRKMFEDYGPVHSLNILRDKNTGQSKGCCFVTFFTRKAAL 317

Query: 73  DAERAISTLNGLRLQSKTIKVSYA----RPSSEVIKDANLYISGLPRTMTQKDVEDMFSR 128
           DA+ A+  +  + +    +++  A    R     +++  L++  L + +++ DV  +F  
Sbjct: 318 DAQNALHNVKTMPMMHHPVQMKPADSEKRNGERNVEERKLFVGMLSKKLSENDVRMLFES 497

Query: 129 FGRIINSRVLVDQTTGLSRGVAFIRFDKRSEAEEAITSFNGHKP-PGSSEPITVKFA 184
           FG I +  VL D + G SRG AFI F  R  A  +I   +  +   G S P+ VK A
Sbjct: 498 FGSIDDCTVLRD-SNGTSRGCAFITFASRQCAMNSIKGMHHSQTMEGCSSPLVVKMA 665

 Score = 50.1 bits (118), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 51/242 (21%), Positives = 95/242 (39%)
 Frame = +3

Query: 65  FVNYVTAKDAERAISTLNGLRLQSKTIKVSYARPSSEVIKDANLYISGLPRTMTQKDVED 124
           FV  V+     R IS  N   +   T   S   P ++ IK   +++  +PR M + ++  
Sbjct: 42  FVFCVSCVCLSREIS--NTSNMNPSTQVTSQGEPDADSIK---MFVGQIPRNMDENELRK 206

Query: 125 MFSRFGRIINSRVLVDQTTGLSRGVAFIRFDKRSEAEEAITSFNGHKPPGSSEPITVKFA 184
           MF  +G + +  +L D+ TG S+G  F+ F  R  A +A  + +                
Sbjct: 207 MFEDYGPVHSLNILRDKNTGQSKGCCFVTFFTRKAALDAQNALH---------------- 338

Query: 185 ANPNQNKNMALLSQLYHSPARRFGGPVHHQAQRFRFSPMGVDHMSGISGVNVPGNASSGW 244
                  N+  +  ++H        PV       +  P   +  +G   V          
Sbjct: 339 -------NVKTMPMMHH--------PV-------QMKPADSEKRNGERNVEERK------ 434

Query: 245 CIFIYNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYEEAAMAIAS 304
            +F+  L +   E  +  +F  FG++ +  V+RD N    +G  F+T  + + A  +I  
Sbjct: 435 -LFVGMLSKKLSENDVRMLFESFGSIDDCTVLRDSNGTS-RGCAFITFASRQCAMNSIKG 608

Query: 305 LN 306
           ++
Sbjct: 609 MH 614

 Score = 38.9 bits (89), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 20/64 (31%), Positives = 36/64 (56%)
 Frame = +3

Query: 246 IFIYNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYEEAAMAIASL 305
           +F+  + ++ DE  L +MF  +G V ++ ++RD NT + KG  FVT    + A  A  +L
Sbjct: 156 MFVGQIPRNMDENELRKMFEDYGPVHSLNILRDKNTGQSKGCCFVTFFTRKAALDAQNAL 335

Query: 306 NGYR 309
           +  +
Sbjct: 336 HNVK 347
>17775
          Length = 1282

 Score = 85.5 bits (210), Expect = 2e-17,   Method: Compositional matrix adjust.
 Identities = 49/151 (32%), Positives = 83/151 (54%), Gaps = 2/151 (1%)
 Frame = -2

Query: 21   NLIVNYLPQNMTQEELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAIST 80
            +L V  L  ++T+  L   FS+ G V S ++ RD +   SLGY +VN+    DAERA+ T
Sbjct: 1191 SLYVGDLHPDVTEAMLFEKFSTAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDT 1012

Query: 81   LNGLRLQSKTIKVSYARPSSEVIKD--ANLYISGLPRTMTQKDVEDMFSRFGRIINSRVL 138
            +N   ++ + I++ +++    V K    N++I  L +T+  K + D FS FG I++ ++ 
Sbjct: 1011 MNFDTVKGRPIRIMWSQRDPSVRKSGVGNVFIKNLDKTIDNKALYDTFSAFGNILSCKIA 832

Query: 139  VDQTTGLSRGVAFIRFDKRSEAEEAITSFNG 169
             D+    S+G  F+ F+    A +AI   NG
Sbjct: 831  CDEQG--SKGYGFVHFETEEAARQAIDKVNG 745

 Score = 72.8 bits (177), Expect = 2e-13,   Method: Compositional matrix adjust.
 Identities = 76/318 (23%), Positives = 133/318 (41%), Gaps = 9/318 (2%)
 Frame = -2

Query: 18  GRTNLIVNYLPQNMTQEELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERA 77
           G  N+ +  L + +  + L   FS+ G + S K+  D+    S GYGFV++ T + A +A
Sbjct: 936 GVGNVFIKNLDKTIDNKALYDTFSAFGNILSCKIACDEQG--SKGYGFVHFETEEAARQA 763

Query: 78  ISTLNGLRLQSKTIKVSYARPSSEVI--------KDANLYISGLPRTMTQKDVEDMFSRF 129
           I  +NG+ L  K + V    P  E I        +  N+Y+         +    +  + 
Sbjct: 762 IDKVNGMLLNGKKVYVGRFIPRKERIMMMGDKLKRFNNVYVKNFC*GTG*RPAA*LVWQA 583

Query: 130 GRIINSRVLVDQTTGLSRGVAFIRFDKRSEAEEAITSFNGHKPPGSSEPITVKFAANPNQ 189
            +            G SRG  F+ F++   AE+A+   NG +  G               
Sbjct: 582 RQDHLXXGACRGEDGKSRGFGFVSFEEPEGAEKAVDEINGTEVSGRI------------- 442

Query: 190 NKNMALLSQLYHSPARRFGGPVHHQAQ-RFRFSPMGVDHMSGISGVNVPGNASSGWCIFI 248
                    +Y   A++       QA+ + RF  + ++ ++   GVN          +++
Sbjct: 441 ---------IYCGRAQK---RAERQAELKERFEKIKLERINRYQGVN----------LYV 328

Query: 249 YNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYEEAAMAIASLNGY 308
            NL    D+  L + F  FG +T+ K++ +    + KGFGFV  ++ EEA  A+  +NG 
Sbjct: 327 KNLDDSIDDERLRKEFSNFGTITSAKIMTE--GGRSKGFGFVCFSSPEEATKAVTEMNGR 154

Query: 309 RLGDKILQVSFKTNKSHK 326
            +  K L V+    K  +
Sbjct: 153 IIVAKPLYVALAQRKEDR 100
>03744
          Length = 3486

 Score = 68.9 bits (167), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 53/140 (37%), Positives = 70/140 (50%), Gaps = 3/140 (2%)
 Frame = -1

Query: 190  NKNMALLSQLY---HSPARRFGGPVHHQAQRFRFSPMGVDHMSGISGVNVPGNASSGWCI 246
            N  M  LSQ Y      A  F    + QAQ  + +  G        G  VPG    G  +
Sbjct: 3369 NSGMDALSQAYSGIQQYAASFPNAFNPQAQMQQANSAGKHS----EGPRVPG--PDGANL 3208

Query: 247  FIYNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYEEAAMAIASLN 306
            FIY+L Q+  +  L QMF PFG V + KV  D  TN  K FGFV+  +   A  AI S+N
Sbjct: 3207 FIYHLPQEFGDQDLMQMFMPFGNVVSAKVFIDKQTNLSKCFGFVSYDSPLAAQAAITSMN 3028

Query: 307  GYRLGDKILQVSFKTNKSHK 326
            G+++G K L+V  K +K+ K
Sbjct: 3027 GFQIGMKRLKVQLKRSKNDK 2968

 Score = 56.2 bits (134), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 28/78 (35%), Positives = 44/78 (56%)
 Frame = -1

Query: 20   TNLIVNYLPQNMTQEELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAIS 79
             NL + +LPQ    ++L  +F   G V SAK+  DK    S  +GFV+Y +   A+ AI+
Sbjct: 3216 ANLFIYHLPQEFGDQDLMQMFMPFGNVVSAKVFIDKQTNLSKCFGFVSYDSPLAAQAAIT 3037

Query: 80   TLNGLRLQSKTIKVSYAR 97
            ++NG ++  K +KV   R
Sbjct: 3036 SMNGFQIGMKRLKVQLKR 2983
>20488
          Length = 3281

 Score = 67.0 bits (162), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 50/139 (35%), Positives = 71/139 (51%), Gaps = 2/139 (1%)
 Frame = +2

Query: 190  NKNMALLSQLYHSPARRFG--GPVHHQAQRFRFSPMGVDHMSGISGVNVPGNASSGWCIF 247
            N  M  LSQ Y    +  G  G V+  +    F+P      +  +G +  G    G  +F
Sbjct: 2546 NSGMDALSQAYSGIQQYAGLSGLVNQASFPNAFNPQAQMQQANSAGKHSEG--PDGANLF 2719

Query: 248  IYNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYEEAAMAIASLNG 307
            IY+L Q+  +  L QMF PFG V + KV  D  TN  K FGFV+  +   A  AI S+NG
Sbjct: 2720 IYHLPQEFGDQDLMQMFMPFGNVVSAKVFIDKQTNLSKCFGFVSYDSPLAAQAAITSMNG 2899

Query: 308  YRLGDKILQVSFKTNKSHK 326
            +++G K L+V  K +K+ K
Sbjct: 2900 FQIGMKRLKVQLKRSKNDK 2956

 Score = 55.5 bits (132), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 28/82 (34%), Positives = 46/82 (56%)
 Frame = +2

Query: 20   TNLIVNYLPQNMTQEELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAIS 79
             NL + +LPQ    ++L  +F   G V SAK+  DK    S  +GFV+Y +   A+ AI+
Sbjct: 2708 ANLFIYHLPQEFGDQDLMQMFMPFGNVVSAKVFIDKQTNLSKCFGFVSYDSPLAAQAAIT 2887

Query: 80   TLNGLRLQSKTIKVSYARPSSE 101
            ++NG ++  K +KV   R  ++
Sbjct: 2888 SMNGFQIGMKRLKVQLKRSKND 2953
>11019
          Length = 552

 Score = 66.2 bits (160), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 43/163 (26%), Positives = 76/163 (46%), Gaps = 26/163 (15%)
 Frame = -1

Query: 27  LPQNMTQEELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAISTLNGLR- 85
           L    T E LRS F   GE++ + +++D  +  S G+GFV Y    + +  ++  NG   
Sbjct: 543 LSWQTTTETLRSYFEKFGEIKESMVMKDPTSKRSRGFGFVTYKDPSNVDNVLA--NGPHC 370

Query: 86  LQSKTI-----------------------KVSYARPSSE--VIKDANLYISGLPRTMTQK 120
           + SKT+                       KV++ R S+   V K   +++ GL  + T +
Sbjct: 369 IDSKTLNFSNMTTFYSNQDLLPYPPQVDPKVAFPRKSNPRMVTKTKKIFVGGLSSSTTVE 190

Query: 121 DVEDMFSRFGRIINSRVLVDQTTGLSRGVAFIRFDKRSEAEEA 163
           D+++ F  +G I  + ++ D+ T   RG AF+ FD  S  ++ 
Sbjct: 189 DIKNYFKAYGTIEEATLMFDKVTSRHRGFAFVTFDNESTVDKV 61

 Score = 40.4 bits (93), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 44/208 (21%), Positives = 75/208 (36%)
 Frame = -1

Query: 110 ISGLPRTMTQKDVEDMFSRFGRIINSRVLVDQTTGLSRGVAFIRFDKRSEAEEAITSFNG 169
           I GL    T + +   F +FG I  S V+ D T+  SRG  F+ +   S  +  +   NG
Sbjct: 552 IGGLSWQTTTETLRSYFEKFGEIKESMVMKDPTSKRSRGFGFVTYKDPSNVDNVLA--NG 379

Query: 170 HKPPGSSEPITVKFAANPNQNKNMALLSQLYHSPARRFGGPVHHQAQRFRFSPMGVDHMS 229
              P   +  T+ F+       N  LL                         P  VD   
Sbjct: 378 ---PHCIDSKTLNFSNMTTFYSNQDLLPY-----------------------PPQVDPKV 277

Query: 230 GISGVNVPGNASSGWCIFIYNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCKGFGF 289
                + P   +    IF+  L        +   F  +G +    ++ D  T++ +GF F
Sbjct: 276 AFPRKSNPRMVTKTKKIFVGGLSSSTTVEDIKNYFKAYGTIEEATLMFDKVTSRHRGFAF 97

Query: 290 VTMTNYEEAAMAIASLNGYRLGDKILQV 317
           VT  N E     +  ++ + +  K+++ 
Sbjct: 96  VTFDN-ESTVDKVCEIHFHEINSKMVET 16
>03406
          Length = 1292

 Score = 63.2 bits (152), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 47/169 (27%), Positives = 74/169 (43%)
 Frame = +3

Query: 22  LIVNYLPQNMTQEELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAISTL 81
           + V  L      + LR  F   GEV S  L  D  +G S G+GFV +  A   + A+   
Sbjct: 246 IFVGGLSWETXSKHLREYFEKFGEVTSCTLKTDLDSGKSRGFGFVVFKEAATVD-AVVKN 422

Query: 82  NGLRLQSKTIKVSYARPSSEVIKDANLYISGLPRTMTQKDVEDMFSRFGRIINSRVLVDQ 141
              +LQ + I    A P   + K   +++  L   + Q+DVE  F++FG+++N  +  D+
Sbjct: 423 KEHKLQGRKIDPKPANPRKGMRK---IFVGKLDPGVPQEDVESYFAKFGKVVNVELPYDK 593

Query: 142 TTGLSRGVAFIRFDKRSEAEEAITSFNGHKPPGSSEPITVKFAANPNQN 190
                R   F+ FD     ++ +     HK  G  E    K   NP Q+
Sbjct: 594 VKDQRRAFCFVEFDNDKTVKKVLEQ-TSHK-IGGQEVDVKKATPNPAQS 734

 Score = 34.3 bits (77), Expect = 0.065,   Method: Compositional matrix adjust.
 Identities = 20/58 (34%), Positives = 30/58 (51%)
 Frame = +3

Query: 246 IFIYNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYEEAAMAIA 303
           IF+  L  +     L + F  FG VT+  +  D ++ K +GFGFV    ++EAA   A
Sbjct: 246 IFVGGLSWETXSKHLREYFEKFGEVTSCTLKTDLDSGKSRGFGFVV---FKEAATVDA 410
>19868
          Length = 434

 Score = 61.6 bits (148), Expect = 4e-10,   Method: Compositional matrix adjust.
 Identities = 35/144 (24%), Positives = 67/144 (46%), Gaps = 4/144 (2%)
 Frame = +2

Query: 21  NLIVNYLPQNMTQEELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAIST 80
            + V  L    + E LR  F+  GE+    +++D     S G+GF+ +      ++ ++ 
Sbjct: 2   KMFVGGLSWQTSPESLRDYFNKFGEITEVMVMKDPTTRRSRGFGFITFGDPASVDKVLAQ 181

Query: 81  ----LNGLRLQSKTIKVSYARPSSEVIKDANLYISGLPRTMTQKDVEDMFSRFGRIINSR 136
               L+G ++  K      A P   V +   +++ GL    T +DV++ F +FG I ++ 
Sbjct: 182 ATHELDGKKIDPKVAFPRRAHPRM-VTRTKKIFVGGLSAPTTLEDVKNYFEQFGPIEDAM 358

Query: 137 VLVDQTTGLSRGVAFIRFDKRSEA 160
           ++ D+ T   RG  F+   KR  +
Sbjct: 359 LMFDKQTNRHRGFGFVTISKRRHS 430

 Score = 37.4 bits (85), Expect = 0.009,   Method: Compositional matrix adjust.
 Identities = 21/73 (28%), Positives = 34/73 (46%), Gaps = 4/73 (5%)
 Frame = +2

Query: 246 IFIYNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYEEA----AMA 301
           +F+  L        L   F  FG +T V V++D  T + +GFGF+T  +        A A
Sbjct: 5   MFVGGLSWQTSPESLRDYFNKFGEITEVMVMKDPTTRRSRGFGFITFGDPASVDKVLAQA 184

Query: 302 IASLNGYRLGDKI 314
              L+G ++  K+
Sbjct: 185 THELDGKKIDPKV 223

 Score = 36.2 bits (82), Expect = 0.017,   Method: Compositional matrix adjust.
 Identities = 17/58 (29%), Positives = 30/58 (51%)
 Frame = +2

Query: 107 NLYISGLPRTMTQKDVEDMFSRFGRIINSRVLVDQTTGLSRGVAFIRFDKRSEAEEAI 164
            +++ GL    + + + D F++FG I    V+ D TT  SRG  FI F   +  ++ +
Sbjct: 2   KMFVGGLSWQTSPESLRDYFNKFGEITEVMVMKDPTTRRSRGFGFITFGDPASVDKVL 175

 Score = 29.6 bits (65), Expect = 2.0,   Method: Compositional matrix adjust.
 Identities = 12/31 (38%), Positives = 20/31 (64%)
 Frame = +2

Query: 264 FGPFGAVTNVKVIRDFNTNKCKGFGFVTMTN 294
           F  FG + +  ++ D  TN+ +GFGFVT++ 
Sbjct: 326 FEQFGPIEDAMLMFDKQTNRHRGFGFVTISK 418
>03000
          Length = 778

 Score = 61.2 bits (147), Expect = 6e-10,   Method: Compositional matrix adjust.
 Identities = 37/148 (25%), Positives = 71/148 (47%), Gaps = 5/148 (3%)
 Frame = +3

Query: 22  LIVNYLPQNMTQEELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAIST- 80
           L +  L     ++ LRS F + GE+    ++RD  +  S G+GF+ Y  A+  ++A +  
Sbjct: 93  LFIGGLSYETDEDSLRSHFETWGEIVDCIVMRDSNSKRSRGFGFITYKDAESIDQAQANR 272

Query: 81  ---LNGLRLQSKTIKVSYARPSSEVIKDA-NLYISGLPRTMTQKDVEDMFSRFGRIINSR 136
              ++G  + +K          SEV +    +++ G+    T+  + D F+ FG I    
Sbjct: 273 PHKIDGREVDTKRAMPREESGRSEVQQSVKKMFVGGVKEDTTEDMIRDTFNEFGEITGVD 452

Query: 137 VLVDQTTGLSRGVAFIRFDKRSEAEEAI 164
           ++ D+ TG +RG  F+ F      ++A+
Sbjct: 453 LIQDKGTGKNRGFCFVTFGDHDSVDKAV 536

 Score = 44.3 bits (103), Expect = 7e-05,   Method: Compositional matrix adjust.
 Identities = 46/217 (21%), Positives = 82/217 (37%), Gaps = 4/217 (1%)
 Frame = +3

Query: 98  PSSEVIKDANLYISGLPRTMTQKDVEDMFSRFGRIINSRVLVDQTTGLSRGVAFIRFDKR 157
           P++E  +   L+I GL     +  +   F  +G I++  V+ D  +  SRG  FI + K 
Sbjct: 69  PNAEQFR--KLFIGGLSYETDEDSLRSHFETWGEIVDCIVMRDSNSKRSRGFGFITY-KD 239

Query: 158 SEAEEAITSFNGHKPPGSSEPITVKFAANPNQNKNMALLSQLYHSPARRFGGPVHHQAQR 217
           +E+ +   +   HK  G    +  K A  P +    + + Q                   
Sbjct: 240 AESIDQAQANRPHKIDG--REVDTKRAM-PREESGRSEVQQSVKK--------------- 365

Query: 218 FRFSPMGVDHMSGISGVNVPGNASSGWCIFIYNLGQDADEGILWQMFGPFGAVTNVKVIR 277
                                       +F+  + +D  E ++   F  FG +T V +I+
Sbjct: 366 ----------------------------MFVGGVKEDTTEDMIRDTFNEFGEITGVDLIQ 461

Query: 278 DFNTNKCKGFGFVTMTNYEEAAMAIA----SLNGYRL 310
           D  T K +GF FVT  +++    A+      LNG ++
Sbjct: 462 DKGTGKNRGFCFVTFGDHDSVDKAVLKKRHDLNGRQV 572
>17681
          Length = 964

 Score = 60.5 bits (145), Expect = 9e-10,   Method: Compositional matrix adjust.
 Identities = 28/83 (33%), Positives = 48/83 (57%)
 Frame = +2

Query: 241 SSGWCIFIYNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYEEAAM 300
           SS   IF+ +L  + +   L + F PFG ++N +++RD  T K KG+ FV+     EA  
Sbjct: 23  SSHHHIFVGDLSPEIETETLREAFAPFGEISNCRIVRDPQTMKSKGYAFVSFVKKAEAEN 202

Query: 301 AIASLNGYRLGDKILQVSFKTNK 323
           AI ++NG  +G + ++ ++ T K
Sbjct: 203 AIQAMNGQWIGSRSIRTNWSTRK 271

 Score = 57.0 bits (136), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 45/189 (23%), Positives = 75/189 (39%), Gaps = 45/189 (23%)
 Frame = +2

Query: 21  NLIVNYLPQNMTQEELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAIST 80
           ++ V  L   +  E LR  F+  GE+ + +++RD     S GY FV++V   +AE AI  
Sbjct: 35  HIFVGDLSPEIETETLREAFAPFGEISNCRIVRDPQTMKSKGYAFVSFVKKAEAENAIQA 214

Query: 81  LNGLRLQSKTIKVSYAR----PSSEVIK-------------------------------- 104
           +NG  + S++I+ +++     P  E  K                                
Sbjct: 215 MNGQWIGSRSIRTNWSTRKLPPPRESSKSGGQGGGMGGMGGCGGGAGNGIKNNQRHTFEE 394

Query: 105 --------DANLYISGLPRTMTQKDV-EDMFSRFGRIINSRVLVDQTTGLSRGVAFIRFD 155
                   +  +Y  G P  +   ++    F +FG I + RV  D      +G AFI+F 
Sbjct: 395 VYNQSSPTNTTVYCGGFPPNVISDELMHKHFMQFGPIQDVRVFKD------KGFAFIKFV 556

Query: 156 KRSEAEEAI 164
            +  A  AI
Sbjct: 557 TKEAAARAI 583

 Score = 51.2 bits (121), Expect = 5e-07,   Method: Compositional matrix adjust.
 Identities = 23/72 (31%), Positives = 42/72 (58%)
 Frame = +2

Query: 98  PSSEVIKDANLYISGLPRTMTQKDVEDMFSRFGRIINSRVLVDQTTGLSRGVAFIRFDKR 157
           P +++    ++++  L   +  + + + F+ FG I N R++ D  T  S+G AF+ F K+
Sbjct: 8   PKTDISSHHHIFVGDLSPEIETETLREAFAPFGEISNCRIVRDPQTMKSKGYAFVSFVKK 187

Query: 158 SEAEEAITSFNG 169
           +EAE AI + NG
Sbjct: 188 AEAENAIQAMNG 223
>08958
          Length = 680

 Score = 60.1 bits (144), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 41/151 (27%), Positives = 76/151 (50%)
 Frame = +2

Query: 18  GRTNLIVNYLPQNMTQEELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERA 77
           GR  L V  L  ++++++ + LFS  GEV  A            G+GF+      +AE A
Sbjct: 62  GRCRLFVGNLTPDVSEDDFKKLFSPFGEVSEA------YVNSGRGFGFIRLDYRHNAEAA 223

Query: 78  ISTLNGLRLQSKTIKVSYARPSSEVIKDANLYISGLPRTMTQKDVEDMFSRFGRIINSRV 137
            + L+GL+ + ++++V YA         A L +  L   ++ + +E  F++FG +  + V
Sbjct: 224 KAALDGLQRKGRSLRVRYA------THGAALKVKNLHPYVSNELLEQAFTQFGDLERAIV 385

Query: 138 LVDQTTGLSRGVAFIRFDKRSEAEEAITSFN 168
           +VD+  G S G   + F ++  A++A+   N
Sbjct: 386 IVDE-RGRSTGEGVVEFVRKPGAQQALRRIN 475

 Score = 44.7 bits (104), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 26/82 (31%), Positives = 42/82 (51%), Gaps = 1/82 (1%)
 Frame = +2

Query: 242 SGWC-IFIYNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYEEAAM 300
           +G C +F+ NL  D  E    ++F PFG V+   V      N  +GFGF+ +     A  
Sbjct: 59  TGRCRLFVGNLTPDVSEDDFKKLFSPFGEVSEAYV------NSGRGFGFIRLDYRHNAEA 220

Query: 301 AIASLNGYRLGDKILQVSFKTN 322
           A A+L+G +   + L+V + T+
Sbjct: 221 AKAALDGLQRKGRSLRVRYATH 286
>13457
          Length = 4857

 Score = 58.9 bits (141), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 31/88 (35%), Positives = 51/88 (57%), Gaps = 1/88 (1%)
 Frame = -1

Query: 98   PSSEVIKDANLYISGLPRTMTQKDVEDMFSRFGRIINSRVLVDQTTGLSRGVAFIRFDKR 157
            P   + +D  L++  L +  T++DV  +F  +G I    +L DQ  G S+G AF+++   
Sbjct: 3432 PKMTIGEDRKLFVGMLNKQQTEEDVRQLFHPYGAIEECTILRDQN-GNSKGCAFVKYSTH 3256

Query: 158  SEAEEAITSFNGHKP-PGSSEPITVKFA 184
            SEA+ AI + +G +  PG+S  + VKFA
Sbjct: 3255 SEAQAAINALHGSQTMPGASSSLVVKFA 3172

 Score = 41.2 bits (95), Expect(2) = 3e-08,   Method: Compositional matrix adjust.
 Identities = 21/46 (45%), Positives = 26/46 (56%)
 Frame = -3

Query: 243  GWCIFIYNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCKGFG 288
            G  +FIY+L Q   +  L QMF PFG V + KV  D  TN+ K  G
Sbjct: 2425 GCNLFIYHLPQXXGDAELAQMFVPFGNVISAKVYVDRATNQSKCLG 2288

 Score = 33.9 bits (76), Expect(2) = 3e-08,   Method: Compositional matrix adjust.
 Identities = 16/37 (43%), Positives = 23/37 (62%)
 Frame = -2

Query: 287  FGFVTMTNYEEAAMAIASLNGYRLGDKILQVSFKTNK 323
            FGFV+  N   A  AI ++NG+++G K L+V  K  K
Sbjct: 2294 FGFVSFDNPASAQAAIQAMNGFQIGMKRLKVQLKRPK 2184

 Score = 33.9 bits (76), Expect(2) = 4e-05,   Method: Compositional matrix adjust.
 Identities = 17/45 (37%), Positives = 25/45 (55%)
 Frame = -2

Query: 63   YGFVNYVTAKDAERAISTLNGLRLQSKTIKVSYARPSSEVIKDAN 107
            +GFV++     A+ AI  +NG ++  K +KV   RP     KDAN
Sbjct: 2294 FGFVSFDNPASAQAAIQAMNGFQIGMKRLKVQLKRP-----KDAN 2175

 Score = 30.4 bits (67), Expect(2) = 4e-05,   Method: Compositional matrix adjust.
 Identities = 15/40 (37%), Positives = 20/40 (50%)
 Frame = -3

Query: 21   NLIVNYLPQNMTQEELRSLFSSIGEVESAKLIRDKVAGHS 60
            NL + +LPQ     EL  +F   G V SAK+  D+    S
Sbjct: 2419 NLFIYHLPQXXGDAELAQMFVPFGNVISAKVYVDRATNQS 2300

 Score = 43.5 bits (101), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 24/77 (31%), Positives = 37/77 (48%), Gaps = 13/77 (16%)
 Frame = -1

Query: 244  WC-------------IFIYNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFV 290
            WC             +F+  L +   E  + Q+F P+GA+    ++RD N N  KG  FV
Sbjct: 3447 WCRLTPKMTIGEDRKLFVGMLNKQQTEEDVRQLFHPYGAIEECTILRDQNGNS-KGCAFV 3271

Query: 291  TMTNYEEAAMAIASLNG 307
              + + EA  AI +L+G
Sbjct: 3270 KYSTHSEAQAAINALHG 3220
>12350
          Length = 975

 Score = 58.2 bits (139), Expect = 5e-09,   Method: Compositional matrix adjust.
 Identities = 30/135 (22%), Positives = 70/135 (51%)
 Frame = -2

Query: 20  TNLIVNYLPQNMTQEELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAIS 79
           ++LIV  LP   T+++LRS FS  G++   ++ +D   G S G+GF+ +   +   + ++
Sbjct: 620 SDLIVLGLPWKSTEDDLRSYFSQFGDLLMVQVKKDPKTGQSKGFGFIRFAEYESQLKCMA 441

Query: 80  TLNGLRLQSKTIKVSYARPSSEVIKDANLYISGLPRTMTQKDVEDMFSRFGRIINSRVLV 139
             + +  +   +++  ++  ++ + +  +++      MT  D+   FS+FG +++  V +
Sbjct: 440 QRHMIDGRWCDVRIPNSKEGAQQLMNRKIFVGRCTDDMTADDLRQFFSKFGEVVD--VFI 267

Query: 140 DQTTGLSRGVAFIRF 154
            +     R  AF+ F
Sbjct: 266 PRPF---RAFAFVSF 231

 Score = 45.1 bits (105), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 23/56 (41%), Positives = 33/56 (58%)
 Frame = -2

Query: 99  SSEVIKDANLYISGLPRTMTQKDVEDMFSRFGRIINSRVLVDQTTGLSRGVAFIRF 154
           SS   K ++L + GLP   T+ D+   FS+FG ++  +V  D  TG S+G  FIRF
Sbjct: 641 SSSRQKCSDLIVLGLPWKSTEDDLRSYFSQFGDLLMVQVKKDPKTGQSKGFGFIRF 474

 Score = 35.0 bits (79), Expect = 0.040,   Method: Compositional matrix adjust.
 Identities = 18/58 (31%), Positives = 27/58 (46%)
 Frame = -2

Query: 246 IFIYNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYEEAAMAIA 303
           + +  L   + E  L   F  FG +  V+V +D  T + KGFGF+    YE     +A
Sbjct: 614 LIVLGLPWKSTEDDLRSYFSQFGDLLMVQVKKDPKTGQSKGFGFIRFAEYESQLKCMA 441
>14637
          Length = 455

 Score = 57.8 bits (138), Expect = 6e-09,   Method: Compositional matrix adjust.
 Identities = 32/68 (47%), Positives = 42/68 (61%)
 Frame = -1

Query: 243 GWCIFIYNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYEEAAMAI 302
           G  +FIY+L Q+  +  L QMF PFG V + KV  D  TN  K FGFV+  +   A  AI
Sbjct: 206 GSNLFIYHLPQEFGDQDLMQMFMPFGNVISAKVFIDKQTNLSKCFGFVSYDSPMSAQDAI 27

Query: 303 ASLNGYRL 310
           +S+NG+RL
Sbjct: 26  SSMNGFRL 3

 Score = 55.1 bits (131), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 27/67 (40%), Positives = 40/67 (59%)
 Frame = -1

Query: 20  TNLIVNYLPQNMTQEELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAIS 79
           +NL + +LPQ    ++L  +F   G V SAK+  DK    S  +GFV+Y +   A+ AIS
Sbjct: 203 SNLFIYHLPQEFGDQDLMQMFMPFGNVISAKVFIDKQTNLSKCFGFVSYDSPMSAQDAIS 24

Query: 80  TLNGLRL 86
           ++NG RL
Sbjct: 23  SMNGFRL 3
>14258
          Length = 1063

 Score = 55.8 bits (133), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 31/67 (46%), Positives = 41/67 (61%)
 Frame = +2

Query: 260 LWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYEEAAMAIASLNGYRLGDKILQVSF 319
           L QMF PFG V + KV  D  TN  K FGFV+  +   A  AI+S+NG+++G K L+V  
Sbjct: 110 LMQMFMPFGNVISAKVFIDKQTNLSKCFGFVSYDSPMSAQDAISSMNGFQIGMKRLKVQL 289

Query: 320 KTNKSHK 326
           K  K+ K
Sbjct: 290 KRPKNDK 310

 Score = 51.2 bits (121), Expect = 6e-07,   Method: Compositional matrix adjust.
 Identities = 25/68 (36%), Positives = 40/68 (58%)
 Frame = +2

Query: 34  EELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAISTLNGLRLQSKTIKV 93
           ++L  +F   G V SAK+  DK    S  +GFV+Y +   A+ AIS++NG ++  K +KV
Sbjct: 104 QDLMQMFMPFGNVISAKVFIDKQTNLSKCFGFVSYDSPMSAQDAISSMNGFQIGMKRLKV 283

Query: 94  SYARPSSE 101
              RP ++
Sbjct: 284 QLKRPKND 307
>01278
          Length = 1082

 Score = 53.9 bits (128), Expect = 9e-08,   Method: Compositional matrix adjust.
 Identities = 29/98 (29%), Positives = 51/98 (52%)
 Frame = +2

Query: 4   GYEDHMAEDCRDDIGRTNLIVNYLPQNMTQEELRSLFSSIGEVESAKLIRDKVAGHSLGY 63
           G  + MA   +D+     + V  L ++  + +L+ LF   G +    L +DKV G S G+
Sbjct: 593 GRGESMANQRKDEAA--TIRVTNLSEDTRESDLQELFRPFGPISRIYLAKDKVTGQSKGF 766

Query: 64  GFVNYVTAKDAERAISTLNGLRLQSKTIKVSYARPSSE 101
            F+N+   +DA RAI+ ++G       + V +A+PS +
Sbjct: 767 AFINFHRREDASRAIAGVSGFGYDHLILNVEWAKPSGQ 880

 Score = 52.8 bits (125), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 25/74 (33%), Positives = 42/74 (56%)
 Frame = +2

Query: 246 IFIYNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYEEAAMAIASL 305
           I + NL +D  E  L ++F PFG ++ + + +D  T + KGF F+     E+A+ AIA +
Sbjct: 641 IRVTNLSEDTRESDLQELFRPFGPISRIYLAKDKVTGQSKGFAFINFHRREDASRAIAGV 820

Query: 306 NGYRLGDKILQVSF 319
           +G+     IL V +
Sbjct: 821 SGFGYDHLILNVEW 862
>00029
          Length = 2204

 Score = 52.0 bits (123), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 30/76 (39%), Positives = 40/76 (52%)
 Frame = -3

Query: 246  IFIYNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYEEAAMAIASL 305
            IFI NLG D D   L  +F  +G+V    V+        K FGFV M    EA  AI++L
Sbjct: 2130 IFIGNLGDDTDPEELRALFEKYGSVAECDVL--------KNFGFVHMVKKGEADDAISNL 1975

Query: 306  NGYRLGDKILQVSFKT 321
            NGY +G + ++V   T
Sbjct: 1974 NGYNIGGQRMRVELST 1927

 Score = 37.7 bits (86), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 21/73 (28%), Positives = 37/73 (50%)
 Frame = -3

Query: 22   LIVNYLPQNMTQEELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAISTL 81
            + +  L  +   EELR+LF   G V    ++++        +GFV+ V   +A+ AIS L
Sbjct: 2130 IFIGNLGDDTDPEELRALFEKYGSVAECDVLKN--------FGFVHMVKKGEADDAISNL 1975

Query: 82   NGLRLQSKTIKVS 94
            NG  +  + ++V 
Sbjct: 1974 NGYNIGGQRMRVE 1936
>26197
          Length = 1365

 Score = 37.4 bits (85), Expect(2) = 3e-07,   Method: Compositional matrix adjust.
 Identities = 14/48 (29%), Positives = 26/48 (54%)
 Frame = -3

Query: 108  LYISGLPRTMTQKDVEDMFSRFGRIINSRVLVDQTTGLSRGVAFIRFD 155
             ++  L   + Q+DVE  F++FG+++N  +  D+     R   F+ FD
Sbjct: 1045 FFVGKLDPGVPQEDVESYFAKFGKVVNVELPYDKVKDQRRAFCFVEFD 902

 Score = 34.3 bits (77), Expect(2) = 3e-07,   Method: Compositional matrix adjust.
 Identities = 24/77 (31%), Positives = 34/77 (44%)
 Frame = -2

Query: 22   LIVNYLPQNMTQEELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAISTL 81
            + V  L    + + LR  F   GEV S  L  D  +G S G+GFV +  A   + A+   
Sbjct: 1292 IFVGGLSWETSSKHLREYFEKFGEVTSCTLKTDLDSGKSRGFGFVVFKEAVTVD-AVVKN 1116

Query: 82   NGLRLQSKTIKVSYARP 98
               +LQ + I    A P
Sbjct: 1115 KEHKLQGRKIDPKPANP 1065

 Score = 40.4 bits (93), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 27/102 (26%), Positives = 46/102 (45%)
 Frame = -2

Query: 73   DAERAISTLNGLRLQSKTIKVSYARPSSEVIKDANLYISGLPRTMTQKDVEDMFSRFGRI 132
            D+E  +ST +G           Y R  +E   D  +++ GL    + K + + F +FG +
Sbjct: 1361 DSEAVVSTQSG----------HYGREENE--DDRKIFVGGLSWETSSKHLREYFEKFGEV 1218

Query: 133  INSRVLVDQTTGLSRGVAFIRFDKRSEAEEAITSFNGHKPPG 174
             +  +  D  +G SRG  F+ F K +   +A+     HK  G
Sbjct: 1217 TSCTLKTDLDSGKSRGFGFVVF-KEAVTVDAVVKNKEHKLQG 1095

 Score = 33.9 bits (76), Expect = 0.088,   Method: Compositional matrix adjust.
 Identities = 16/47 (34%), Positives = 24/47 (51%)
 Frame = -2

Query: 246  IFIYNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTM 292
            IF+  L  +     L + F  FG VT+  +  D ++ K +GFGFV  
Sbjct: 1292 IFVGGLSWETSSKHLREYFEKFGEVTSCTLKTDLDSGKSRGFGFVVF 1152
>30672
          Length = 877

 Score = 51.6 bits (122), Expect = 4e-07,   Method: Compositional matrix adjust.
 Identities = 46/194 (23%), Positives = 75/194 (38%), Gaps = 45/194 (23%)
 Frame = +3

Query: 21  NLIVNYLPQNMTQEELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAIST 80
            L V  LP   + E+L   F  +G +++A ++  K  G   G+G+V +   +DA +A  T
Sbjct: 15  TLFVRNLPFETSNEKLLEAFEQVGPLKTAFVVAGKEPGKCRGFGYVQFSMLEDAIKAKDT 194

Query: 81  LN----------------------------------GLRLQSKTI-----------KVSY 95
           +                                   G +L S+T            K   
Sbjct: 195 VTHCSGRKISLSFADTKKSWKTKQKGGTETSDALGLGKKLPSQTAVTDGEPNPKPEKKKT 374

Query: 96  ARPSSEVIKDANLYISGLPRTMTQKDVEDMFSRFGRIINSRVLVDQTTGLSRGVAFIRFD 155
            +P  E+ K   L I  L     + D+   F +FG I    + + Q    SRG AF++F 
Sbjct: 375 KQPKQELGKRCRLIIRNLAFKCKEADIRSHFGKFGTISEVTIPLKQG-DRSRGFAFVQFT 551

Query: 156 KRSEAEEAITSFNG 169
           +   A++AI+  NG
Sbjct: 552 EVKAAQKAISDMNG 593

 Score = 42.0 bits (97), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 26/92 (28%), Positives = 44/92 (47%), Gaps = 1/92 (1%)
 Frame = +3

Query: 6   EDHMAEDCRDDIG-RTNLIVNYLPQNMTQEELRSLFSSIGEVESAKLIRDKVAGHSLGYG 64
           E    +  + ++G R  LI+  L     + ++RS F   G + S   I  K    S G+ 
Sbjct: 360 EKKKTKQPKQELGKRCRLIIRNLAFKCKEADIRSHFGKFGTI-SEVTIPLKQGDRSRGFA 536

Query: 65  FVNYVTAKDAERAISTLNGLRLQSKTIKVSYA 96
           FV +   K A++AIS +NG  +  + + V +A
Sbjct: 537 FVQFTEVKAAQKAISDMNGTAIMDRPVAVDWA 632

 Score = 40.8 bits (94), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 46/221 (20%), Positives = 88/221 (39%), Gaps = 4/221 (1%)
 Frame = +3

Query: 107 NLYISGLPRTMTQKDVEDMFSRFGRIINSRVLVDQTTGLSRGVAFIRF---DKRSEAEEA 163
            L++  LP   + + + + F + G +  + V+  +  G  RG  +++F   +   +A++ 
Sbjct: 15  TLFVRNLPFETSNEKLLEAFEQVGPLKTAFVVAGKEPGKCRGFGYVQFSMLEDAIKAKDT 194

Query: 164 ITSFNGHKPPGSSEPITVKFAANPNQNKNMALLSQLYHSPARRFGGPVHHQAQRFRFSPM 223
           +T  +G K       I++ FA +  ++           S A   G  +  Q       P 
Sbjct: 195 VTHCSGRK-------ISLSFA-DTKKSWKTKQKGGTETSDALGLGKKLPSQTAVTDGEP- 347

Query: 224 GVDHMSGISGVNVPGNASSGWC-IFIYNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTN 282
             +          P       C + I NL     E  +   FG FG ++ V +      +
Sbjct: 348 --NPKPEKKKTKQPKQELGKRCRLIIRNLAFKCKEADIRSHFGKFGTISEVTIPLK-QGD 518

Query: 283 KCKGFGFVTMTNYEEAAMAIASLNGYRLGDKILQVSFKTNK 323
           + +GF FV  T  + A  AI+ +NG  + D+ + V +   K
Sbjct: 519 RSRGFAFVQFTEVKAAQKAISDMNGTAIMDRPVAVDWAVAK 641
>16427
          Length = 1313

 Score = 51.2 bits (121), Expect = 5e-07,   Method: Compositional matrix adjust.
 Identities = 26/72 (36%), Positives = 39/72 (54%)
 Frame = +1

Query: 246 IFIYNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYEEAAMAIASL 305
           +F+  L ++ DE +L + F  FG +T   VIRD      +GFGFVT  N  +A  A+  +
Sbjct: 142 LFVGGLAEEIDEKVLEREFSKFGRITESMVIRDKVRQVSRGFGFVTYENPMDAEEAVKHM 321

Query: 306 NGYRLGDKILQV 317
           +G  +  K L V
Sbjct: 322 DGKEILGKKLHV 357

 Score = 50.4 bits (119), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 24/71 (33%), Positives = 41/71 (57%)
 Frame = +1

Query: 101 EVIKDANLYISGLPRTMTQKDVEDMFSRFGRIINSRVLVDQTTGLSRGVAFIRFDKRSEA 160
           E  +   L++ GL   + +K +E  FS+FGRI  S V+ D+   +SRG  F+ ++   +A
Sbjct: 121 EKDRPGKLFVGGLAEEIDEKVLEREFSKFGRITESMVIRDKVRQVSRGFGFVTYENPMDA 300

Query: 161 EEAITSFNGHK 171
           EEA+   +G +
Sbjct: 301 EEAVKHMDGKE 333

 Score = 49.3 bits (116), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 26/76 (34%), Positives = 39/76 (51%)
 Frame = +1

Query: 21  NLIVNYLPQNMTQEELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAIST 80
            L V  L + + ++ L   FS  G +  + +IRDKV   S G+GFV Y    DAE A+  
Sbjct: 139 KLFVGGLAEEIDEKVLEREFSKFGRITESMVIRDKVRQVSRGFGFVTYENPMDAEEAVKH 318

Query: 81  LNGLRLQSKTIKVSYA 96
           ++G  +  K + V  A
Sbjct: 319 MDGKEILGKKLHVEDA 366
>00302
          Length = 927

 Score = 50.1 bits (118), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 26/88 (29%), Positives = 45/88 (51%), Gaps = 1/88 (1%)
 Frame = -1

Query: 239 NASSGWCIFIYNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYEEA 298
           N     C+ I+ L     E  L ++FG +G ++ V+V+ D  T + +GF FV   + E+A
Sbjct: 480 NPDPNRCLGIFGLSLYTQERGLREVFGRYGHISEVQVVYDRQTGRSRGFAFVYFKSSEDA 301

Query: 299 AMAIASLNGYRLGDKILQVSFK-TNKSH 325
             A    NG  +  + ++V F  T ++H
Sbjct: 300 HEAKDRCNGIEIDGRKIRVDFSITERAH 217

 Score = 43.5 bits (101), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 23/62 (37%), Positives = 34/62 (54%)
 Frame = -1

Query: 108 LYISGLPRTMTQKDVEDMFSRFGRIINSRVLVDQTTGLSRGVAFIRFDKRSEAEEAITSF 167
           L I GL     ++ + ++F R+G I   +V+ D+ TG SRG AF+ F    +A EA    
Sbjct: 459 LGIFGLSLYTQERGLREVFGRYGHISEVQVVYDRQTGRSRGFAFVYFKSSEDAHEAKDRC 280

Query: 168 NG 169
           NG
Sbjct: 279 NG 274
>13822
          Length = 963

 Score = 48.9 bits (115), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 32/96 (33%), Positives = 49/96 (51%), Gaps = 3/96 (3%)
 Frame = -1

Query: 231 ISGVNVPGNASSGWC---IFIYNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCKGF 287
           + GV VP  A S      + + N+     E  L Q+ GPFG + +V++I  FN    KGF
Sbjct: 390 VQGVQVPPQAISPEGPKRLHVSNIPFRFREADLRQLLGPFGTILDVEII--FNERGSKGF 217

Query: 288 GFVTMTNYEEAAMAIASLNGYRLGDKILQVSFKTNK 323
           GFVT  +  EA  A   +NG  +  + ++V+  T +
Sbjct: 216 GFVTFAHSAEAERARDKMNGTVVEGRKIEVNNATAR 109

 Score = 38.5 bits (88), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 23/79 (29%), Positives = 42/79 (53%)
 Frame = -1

Query: 18  GRTNLIVNYLPQNMTQEELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERA 77
           G   L V+ +P    + +LR L    G +   ++I ++    S G+GFV +  + +AERA
Sbjct: 348 GPKRLHVSNIPFRFREADLRQLLGPFGTILDVEIIFNERG--SKGFGFVTFAHSAEAERA 175

Query: 78  ISTLNGLRLQSKTIKVSYA 96
              +NG  ++ + I+V+ A
Sbjct: 174 RDKMNGTVVEGRKIEVNNA 118
>00556
          Length = 2189

 Score = 48.9 bits (115), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 22/70 (31%), Positives = 40/70 (57%)
 Frame = +3

Query: 27  LPQNMTQEELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAISTLNGLRL 86
           LP  +++++++ L  S G ++S  L+RD   G S G+ F  Y+     ++A + LNG++L
Sbjct: 780 LPSYLSEDQMKELLLSFGPLKSFNLVRDNATGLSKGFAFCEYLDPSVTDQACAGLNGMQL 959

Query: 87  QSKTIKVSYA 96
             K + V  A
Sbjct: 960 GDKKLIVQRA 989

 Score = 43.5 bits (101), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 20/74 (27%), Positives = 43/74 (58%), Gaps = 2/74 (2%)
 Frame = +3

Query: 100 SEVIKDAN--LYISGLPRTMTQKDVEDMFSRFGRIINSRVLVDQTTGLSRGVAFIRFDKR 157
           S V++D++  +++ GLP  +++  ++++   FG + +  ++ D  TGLS+G AF  +   
Sbjct: 735 STVVQDSDHKIFMGGLPSYLSEDQMKELLLSFGPLKSFNLVRDNATGLSKGFAFCEYLDP 914

Query: 158 SEAEEAITSFNGHK 171
           S  ++A    NG +
Sbjct: 915 SVTDQACAGLNGMQ 956

 Score = 39.7 bits (91), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 29/87 (33%), Positives = 39/87 (44%), Gaps = 5/87 (5%)
 Frame = +3

Query: 236 VPGNAS-----SGWCIFIYNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFV 290
           VPG  S     S   IF+  L     E  + ++   FG + +  ++RD  T   KGF F 
Sbjct: 720 VPGVVSTVVQDSDHKIFMGGLPSYLSEDQMKELLLSFGPLKSFNLVRDNATGLSKGFAFC 899

Query: 291 TMTNYEEAAMAIASLNGYRLGDKILQV 317
              +      A A LNG +LGDK L V
Sbjct: 900 EYLDPSVTDQACAGLNGMQLGDKKLIV 980
>15371
          Length = 383

 Score = 47.8 bits (112), Expect = 6e-06,   Method: Compositional matrix adjust.
 Identities = 39/105 (37%), Positives = 48/105 (45%), Gaps = 3/105 (2%)
 Frame = -2

Query: 190 NKNMALLSQLY---HSPARRFGGPVHHQAQRFRFSPMGVDHMSGISGVNVPGNASSGWCI 246
           N  M  LSQ Y      A  F    + QAQ  + +  G  H  G  G N          +
Sbjct: 295 NSGMDALSQAYSGIQQYAASFPNAFNPQAQMQQANSAG-KHSEGPDGAN----------L 149

Query: 247 FIYNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVT 291
           FIY+L Q+  +  L QMF PFG V + KV  D  TN  K FGFV+
Sbjct: 148 FIYHLPQEFGDQDLMQMFMPFGNVVSAKVFIDKQTNLSKCFGFVS 14

 Score = 39.7 bits (91), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 19/49 (38%), Positives = 27/49 (55%)
 Frame = -2

Query: 20  TNLIVNYLPQNMTQEELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNY 68
            NL + +LPQ    ++L  +F   G V SAK+  DK    S  +GFV+Y
Sbjct: 157 ANLFIYHLPQEFGDQDLMQMFMPFGNVVSAKVFIDKQTNLSKCFGFVSY 11
>31938
          Length = 746

 Score = 46.2 bits (108), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 24/74 (32%), Positives = 43/74 (58%)
 Frame = +3

Query: 22  LIVNYLPQNMTQEELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAISTL 81
           +++  +P + T + LR  F  +G+V+ A++  + V       G V +   +DAE AI+ +
Sbjct: 267 IVIKNVPLSCTWQTLRDKFRDVGDVKFAEIRGNDV-------GVVRFFKERDAELAIALM 425

Query: 82  NGLRLQSKTIKVSY 95
           +G RL  +TIKV+Y
Sbjct: 426 DGSRLDGRTIKVTY 467
>31618
          Length = 716

 Score = 45.8 bits (107), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 32/85 (37%), Positives = 44/85 (51%), Gaps = 6/85 (7%)
 Frame = +1

Query: 86  LQSKTIKVSYARPSSEVIKDANLYISGLPRTMTQKDVEDMFSRFGRIINSRVLVDQTTGL 145
           LQ    K+   R +S V+    L++ GL    T+K++ D F ++G I +  V  D  TG 
Sbjct: 235 LQMAAQKMQPLRVTS-VMMTEKLFVGGLSWETTEKELRDHFGKYGEIESINVKTDPQTGR 411

Query: 146 SRGVAFIRF------DKRSEAEEAI 164
           SRG AFI F      D+ S AEE I
Sbjct: 412 SRGFAFIVFTNTEAIDQVSAAEEHI 486

 Score = 33.5 bits (75), Expect = 0.11,   Method: Compositional matrix adjust.
 Identities = 34/147 (23%), Positives = 58/147 (39%)
 Frame = +1

Query: 21  NLIVNYLPQNMTQEELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAIST 80
            L V  L    T++ELR  F   GE+ES  +  D   G S G+ F+ + T  +A   +S 
Sbjct: 295 KLFVGGLSWETTEKELRDHFGKYGEIESINVKTDPQTGRSRGFAFIVF-TNTEAIDQVSA 471

Query: 81  LNGLRLQSKTIKVSYARPSSEVIKDANLYISGLPRTMTQKDVEDMFSRFGRIINSRVLVD 140
                + SK +     +P    +  A       P+ +  +  +        I+   +  D
Sbjct: 472 AEEHIINSKKVD-PKKKPR---LAMARFLSVA*PQRLAMRKSKPTSVNLDNIVEVEMPFD 639

Query: 141 QTTGLSRGVAFIRFDKRSEAEEAITSF 167
           +     +G  FI FD    +E+ +T  
Sbjct: 640 KQKSHRKGFXFITFD----SEQVVTDL 708
>12506
          Length = 1056

 Score = 45.4 bits (106), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 21/72 (29%), Positives = 41/72 (56%)
 Frame = -3

Query: 248  IYNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYEEAAMAIASLNG 307
            ++  G+  D+ +L   F PFG + ++++  D+ T K +GF F+     E+AA AI ++N 
Sbjct: 1048 LFTAGE-VDDKVLHAAFLPFGDIVDIQIPLDYETEKHRGFAFIEFELAEDAAAAIDNMNE 872

Query: 308  YRLGDKILQVSF 319
              L  + ++V+ 
Sbjct: 871  SELFGRTIRVNL 836
>31310
          Length = 469

 Score = 44.7 bits (104), Expect = 6e-05,   Method: Compositional matrix adjust.
 Identities = 24/77 (31%), Positives = 42/77 (54%)
 Frame = -3

Query: 246 IFIYNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYEEAAMAIASL 305
           I++ ++  +  E  + Q F PFG + +V +  D  TNK KGF F+     E A +A+  +
Sbjct: 317 IYVGSINFEIREDTIKQAFLPFGPIKSVNLSWDPITNKHKGFSFIEYDVPEAAQLALEQM 138

Query: 306 NGYRLGDKILQVSFKTN 322
           NG  +G + ++V   +N
Sbjct: 137 NGVMIGGRNIKVGRPSN 87

 Score = 38.9 bits (89), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 23/95 (24%), Positives = 44/95 (46%)
 Frame = -3

Query: 6   EDHMAEDCRDDIGRTNLIVNYLPQNMTQEELRSLFSSIGEVESAKLIRDKVAGHSLGYGF 65
           +  +A  CR  +G  N         + ++ ++  F   G ++S  L  D +     G+ F
Sbjct: 344 QQALALMCRIYVGSINF-------EIREDTIKQAFLPFGPIKSVNLSWDPITNKHKGFSF 186

Query: 66  VNYVTAKDAERAISTLNGLRLQSKTIKVSYARPSS 100
           + Y   + A+ A+  +NG+ +  + IKV   RPS+
Sbjct: 185 IEYDVPEAAQLALEQMNGVMIGGRNIKV--GRPSN 87
>32733
          Length = 709

 Score = 44.3 bits (103), Expect = 6e-05,   Method: Compositional matrix adjust.
 Identities = 27/73 (36%), Positives = 38/73 (52%), Gaps = 1/73 (1%)
 Frame = +1

Query: 113 LPRTMTQKDVEDMFSRFGRIINSRVLVDQTTGLSRGVAFIRFDKRSEAEEAITSFNGHKP 172
           L + +++ DV  +F  FG I +  VL D + G SRG AFI F  R  A  +I   +  + 
Sbjct: 487 LSKKLSENDVRMLFESFGSIDDCTVLRD-SNGTSRGCAFITFASRQCAMNSIKGMHHSQT 663

Query: 173 -PGSSEPITVKFA 184
             G S P+ VK A
Sbjct: 664 MEGCSSPLVVKMA 702
>02415
          Length = 2763

 Score = 43.1 bits (100), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 19/56 (33%), Positives = 31/56 (55%)
 Frame = -1

Query: 108  LYISGLPRTMTQKDVEDMFSRFGRIINSRVLVDQTTGLSRGVAFIRFDKRSEAEEA 163
            +++ GLP   T   + + F +FG I  + V+ D+ TG SRG  F+    R+ A+ A
Sbjct: 1920 IFVGGLPYHTTDHSLREYFDKFGDIDEAVVITDRQTGKSRGYGFVTMADRTGADRA 1753

 Score = 35.0 bits (79), Expect = 0.042,   Method: Compositional matrix adjust.
 Identities = 18/49 (36%), Positives = 25/49 (51%)
 Frame = -1

Query: 246  IFIYNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTN 294
            IF+  L     +  L + F  FG +    VI D  T K +G+GFVTM +
Sbjct: 1920 IFVGGLPYHTTDHSLREYFDKFGDIDEAVVITDRQTGKSRGYGFVTMAD 1774
>00738
          Length = 1559

 Score = 43.1 bits (100), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 32/128 (25%), Positives = 56/128 (43%), Gaps = 17/128 (13%)
 Frame = -2

Query: 14   RDDIG---RTNLIVNYLPQNMTQEELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVT 70
            RDD G    T + V  L  + +  E+R  F   G++    + R +         FV Y  
Sbjct: 1294 RDDTGVRVGTRIHVGSLSSSTSTREIREEFKRFGDIIDLWMPRTQPT-----IAFVVYRY 1130

Query: 71   AKDAERAISTLNGLRLQSKTIKVSYARPSSEVIKDANL--------------YISGLPRT 116
             +DAE+AI  ++G  +  + ++VS ARP S+ ++  +                  GLP T
Sbjct: 1129 EEDAEKAIRRMDGESMHGRRVRVSLARPRSQGVRGGSFNPNLRCYQCGRRGALFPGLPST 950

Query: 117  MTQKDVED 124
             +++  +D
Sbjct: 949  ASKQSHQD 926
>02140
          Length = 1796

 Score = 42.7 bits (99), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 23/81 (28%), Positives = 40/81 (49%)
 Frame = +3

Query: 22  LIVNYLPQNMTQEELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAISTL 81
           L V  L    T E+L  +FS  G + S ++IRD     SL Y FV +   +  E A   +
Sbjct: 807 LFVCKLNPVTTDEDLEMIFSRFGPITSCEVIRDHKTKESLQYAFVEFEKPEHCENAYFKM 986

Query: 82  NGLRLQSKTIKVSYARPSSEV 102
           + + +  + I V +++  S++
Sbjct: 987 DNVLIDDRRIHVDFSQSVSKI 1049

 Score = 40.0 bits (92), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 22/59 (37%), Positives = 31/59 (52%)
 Frame = +3

Query: 105 DANLYISGLPRTMTQKDVEDMFSRFGRIINSRVLVDQTTGLSRGVAFIRFDKRSEAEEA 163
           D  L++  L    T +D+E +FSRFG I +  V+ D  T  S   AF+ F+K    E A
Sbjct: 798 DNVLFVCKLNPVTTDEDLEMIFSRFGPITSCEVIRDHKTKESLQYAFVEFEKPEHCENA 974
>23322
          Length = 471

 Score = 42.0 bits (97), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 21/69 (30%), Positives = 37/69 (53%), Gaps = 4/69 (5%)
 Frame = -2

Query: 246 IFIYNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYEEAAMAIA-- 303
           +F+  + +D  E ++   F  FG +T V +I+D  T K +GF FVT  +++    A+   
Sbjct: 404 MFVGGVKEDTTEDMIRDTFNEFGEITGVDLIQDKGTGKNRGFCFVTFGDHDSVDKAVLKK 225

Query: 304 --SLNGYRL 310
              LNG ++
Sbjct: 224 RHDLNGRQV 198
>03200
          Length = 657

 Score = 42.0 bits (97), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 25/77 (32%), Positives = 39/77 (50%)
 Frame = -1

Query: 241 SSGWCIFIYNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYEEAAM 300
           S G  ++++ +G    E IL   F  FG + N+ + R+ N       GFVT    E A  
Sbjct: 495 SKGHTVYVHGIG--VTEDILKSAFSNFGNIVNINIERERNN------GFVTFEKMESADQ 340

Query: 301 AIASLNGYRLGDKILQV 317
           AIA++NG  + +  L+V
Sbjct: 339 AIANMNGSMISNVQLKV 289

 Score = 35.0 bits (79), Expect = 0.038,   Method: Compositional matrix adjust.
 Identities = 22/77 (28%), Positives = 43/77 (55%), Gaps = 2/77 (2%)
 Frame = -1

Query: 31  MTQEELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAISTLNGLRLQSKT 90
           +T++ L+S FS+ G + +  + R++        GFV +   + A++AI+ +NG  + +  
Sbjct: 459 VTEDILKSAFSNFGNIVNINIERER------NNGFVTFEKMESADQAIANMNGSMISNVQ 298

Query: 91  IKVSYAR--PSSEVIKD 105
           +KV  AR  PS + + D
Sbjct: 297 LKVMMARRQPSFDSVND 247
>32386
          Length = 674

 Score = 42.0 bits (97), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 22/65 (33%), Positives = 33/65 (50%)
 Frame = +1

Query: 239 NASSGWCIFIYNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYEEA 298
           NA     +FI  L  + DE  L   F  +G + +  V+RD N+ + +GFGF+T  + E  
Sbjct: 286 NAEQFRKLFIGGLSYETDEDSLRSHFETWGEIVDCIVMRDSNSKRSRGFGFITYKDAESI 465

Query: 299 AMAIA 303
             A A
Sbjct: 466 DQAQA 480

 Score = 36.6 bits (83), Expect = 0.015,   Method: Compositional matrix adjust.
 Identities = 27/106 (25%), Positives = 48/106 (45%)
 Frame = +1

Query: 21  NLIVNYLPQNMTQEELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAIST 80
            L +  L     ++ LRS F + GE+    ++RD  +  S G+GF+ Y  A+  ++A + 
Sbjct: 304 KLFIGGLSYETDEDSLRSHFETWGEIVDCIVMRDSNSKRSRGFGFITYKDAESIDQAQAN 483

Query: 81  LNGLRLQSKTIKVSYARPSSEVIKDANLYISGLPRTMTQKDVEDMF 126
               ++  + +    A P  E         SG  R+  Q+ V+ MF
Sbjct: 484 -RPHKIDGREVDTKRAMPREE---------SG--RSEVQQSVKKMF 585
>33516
          Length = 449

 Score = 42.0 bits (97), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 19/61 (31%), Positives = 33/61 (54%)
 Frame = +1

Query: 106 ANLYISGLPRTMTQKDVEDMFSRFGRIINSRVLVDQTTGLSRGVAFIRFDKRSEAEEAIT 165
             +++ GL     Q  ++  FS+FG I +  V+++Q TG SRG  F+ F   S  +  ++
Sbjct: 154 GKIFVGGLSWDTDQDSLQGYFSQFGEITDCIVMMNQQTGKSRGFGFVSFKDPSTVDVILS 333

Query: 166 S 166
           S
Sbjct: 334 S 336

 Score = 36.6 bits (83), Expect = 0.012,   Method: Compositional matrix adjust.
 Identities = 19/59 (32%), Positives = 31/59 (52%)
 Frame = +1

Query: 246 IFIYNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYEEAAMAIAS 304
           IF+  L  D D+  L   F  FG +T+  V+ +  T K +GFGFV+  +     + ++S
Sbjct: 160 IFVGGLSWDTDQDSLQGYFSQFGEITDCIVMMNQQTGKSRGFGFVSFKDPSTVDVILSS 336

 Score = 33.1 bits (74), Expect = 0.15,   Method: Compositional matrix adjust.
 Identities = 16/55 (29%), Positives = 31/55 (56%)
 Frame = +1

Query: 14  RDDIGRTNLIVNYLPQNMTQEELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNY 68
           R++ G+  + V  L  +  Q+ L+  FS  GE+    ++ ++  G S G+GFV++
Sbjct: 142 REEPGK--IFVGGLSWDTDQDSLQGYFSQFGEITDCIVMMNQQTGKSRGFGFVSF 300
>24983
          Length = 433

 Score = 41.2 bits (95), Expect = 6e-04,   Method: Compositional matrix adjust.
 Identities = 20/59 (33%), Positives = 30/59 (50%)
 Frame = -2

Query: 110 ISGLPRTMTQKDVEDMFSRFGRIINSRVLVDQTTGLSRGVAFIRFDKRSEAEEAITSFN 168
           + GLP   T   + + F +FG I  + V+ D+ TG SRG  F+    R+ A+ A    N
Sbjct: 303 LGGLPYHTTDHSLREYFDKFGDIDEAVVITDRQTGKSRGYGFVTMADRTGADRACKDPN 127

 Score = 34.3 bits (77), Expect = 0.067,   Method: Compositional matrix adjust.
 Identities = 18/47 (38%), Positives = 23/47 (48%)
 Frame = -2

Query: 260 LWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYEEAAMAIASLN 306
           L + F  FG +    VI D  T K +G+GFVTM +   A  A    N
Sbjct: 267 LREYFDKFGDIDEAVVITDRQTGKSRGYGFVTMADRTGADRACKDPN 127
>01065
          Length = 1033

 Score = 40.4 bits (93), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 23/89 (25%), Positives = 43/89 (48%)
 Frame = +2

Query: 20  TNLIVNYLPQNMTQEELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAIS 79
           T + V  L  + +  E+R  F   G++    + R +         FV Y   +DAE+AI 
Sbjct: 14  TRIHVGSLSSSTSTREIREEFKRFGDIIDLWMPRTQPT-----IAFVVYRYEEDAEKAIR 178

Query: 80  TLNGLRLQSKTIKVSYARPSSEVIKDANL 108
            ++G  +  + ++VS ARP S+ ++  + 
Sbjct: 179 RMDGESMHGRRVRVSLARPRSQGVRGGSF 265
>09968
          Length = 2913

 Score = 39.7 bits (91), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 27/88 (30%), Positives = 42/88 (47%), Gaps = 3/88 (3%)
 Frame = -1

Query: 14   RDDIGRT---NLIVNYLPQNMTQEELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVT 70
            +DD   T   NL V+ L  +    +L+SLF   G+V  AK++ +  +   L +GFV   +
Sbjct: 1419 KDDKATTSIRNLWVSGLSSSTRATDLKSLFGKHGKVIGAKVVTNTRSPGRLCFGFVTMAS 1240

Query: 71   AKDAERAISTLNGLRLQSKTIKVSYARP 98
            A +  + I  L+   L  K I V    P
Sbjct: 1239 ADETTKCIQHLHRTELHGKMISVERFSP 1156

 Score = 33.9 bits (76), Expect = 0.095,   Method: Compositional matrix adjust.
 Identities = 20/72 (27%), Positives = 32/72 (44%)
 Frame = -1

Query: 246  IFIYNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYEEAAMAIASL 305
            +++  L        L  +FG  G V   KV+ +  +     FGFVTM + +E    I  L
Sbjct: 1386 LWVSGLSSSTRATDLKSLFGKHGKVIGAKVVTNTRSPGRLCFGFVTMASADETTKCIQHL 1207

Query: 306  NGYRLGDKILQV 317
            +   L  K++ V
Sbjct: 1206 HRTELHGKMISV 1171
>25632
          Length = 864

 Score = 38.5 bits (88), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 20/57 (35%), Positives = 29/57 (50%)
 Frame = -2

Query: 267 FGAVTNVKVIRDFNTNKCKGFGFVTMTNYEEAAMAIASLNGYRLGDKILQVSFKTNK 323
           +G V    V+        K +GFV M    EA+ AI +LNGY +  + ++V   TNK
Sbjct: 698 YGTVEECDVL--------KNYGFVHMPTKSEASAAITNLNGYNIKGQRMRVELSTNK 552

 Score = 28.9 bits (63), Expect = 2.7,   Method: Compositional matrix adjust.
 Identities = 15/55 (27%), Positives = 27/55 (49%)
 Frame = -2

Query: 40  FSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAISTLNGLRLQSKTIKVS 94
               G VE   ++++        YGFV+  T  +A  AI+ LNG  ++ + ++V 
Sbjct: 707 LEKYGTVEECDVLKN--------YGFVHMPTKSEASAAITNLNGYNIKGQRMRVE 567
>28652
          Length = 918

 Score = 38.5 bits (88), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 32/129 (24%), Positives = 56/129 (43%), Gaps = 5/129 (3%)
 Frame = -2

Query: 187 PNQNKNMALLSQLYH-----SPARRFGGPVHHQAQRFRFSPMGVDHMSGISGVNVPGNAS 241
           P++ K  A+L +  +     +  R++GGP           P   D   G           
Sbjct: 854 PDEAKIQAILKRTGYELDVTTGQRKYGGP----------PPGWTDPQPG----------- 738

Query: 242 SGWCIFIYNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYEEAAMA 301
           SG  +F   + +D  E  L  +F   G + +++++ D  +N  +G+ FVT T  E AA A
Sbjct: 737 SGHEVFCGKIPRDIFEDELIPLFEDCGTIWDLRLMMDPVSNLNRGYCFVTYTTKEAAAEA 558

Query: 302 IASLNGYRL 310
           +   +GY +
Sbjct: 557 VKQHDGYEI 531
>31265
          Length = 540

 Score = 38.1 bits (87), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 47/180 (26%), Positives = 74/180 (41%), Gaps = 13/180 (7%)
 Frame = +2

Query: 62  GYGFVNYVTAKDAERAISTLNGLRLQ--SKTIKVSYARPSSEVIKDAN-----LYISGLP 114
           G+ FV Y + + A  A   L   R+Q     I V +A P  +V +D       L +  L 
Sbjct: 5   GFAFVEYTSHRAAAMARRKLIPGRIQLWGHQIAVDWAEPEQDVDEDTMSQVKILXVRNLM 184

Query: 115 RTMTQKDVEDMFSRF--GRIINSRVLVDQTTGLSRGVAFIRFDKRSEAEEAITSFNGHKP 172
            T T++ ++D+FSR   GR I     +       R  AF+ F  R +A +A+   +G   
Sbjct: 185 LTTTEETLKDVFSRAAGGREIERVKKI-------RDYAFVHFRSREDAIKAMDVTDGSTI 343

Query: 173 PGSSEPITVKFAANPNQNKNMALLS----QLYHSPARRFGGPVHHQAQRFRFSPMGVDHM 228
            GS   + +   A P    ++ L      Q+Y       G   + Q+  F   P+G   M
Sbjct: 344 EGSQVEVVL---AKPVDKTDIRLAKARGLQVY-------GFDNYEQSTPFPSQPLGYGQM 493

 Score = 37.4 bits (85), Expect = 0.009,   Method: Compositional matrix adjust.
 Identities = 24/80 (30%), Positives = 40/80 (50%), Gaps = 3/80 (3%)
 Frame = +2

Query: 22  LIVNYLPQNMTQEELRSLFSSIG---EVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAI 78
           L V  L    T+E L+ +FS      E+E  K IRD        Y FV++ + +DA +A+
Sbjct: 164 LXVRNLMLTTTEETLKDVFSRAAGGREIERVKKIRD--------YAFVHFRSREDAIKAM 319

Query: 79  STLNGLRLQSKTIKVSYARP 98
              +G  ++   ++V  A+P
Sbjct: 320 DVTDGSTIEGSQVEVVLAKP 379
>04988
          Length = 705

 Score = 37.7 bits (86), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 22/81 (27%), Positives = 37/81 (45%)
 Frame = -3

Query: 20  TNLIVNYLPQNMTQEELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAIS 79
           T + +  LP    ++++   F   G V    L          GYGFV +   +DA+ A+ 
Sbjct: 652 TRVYIGRLPYQAREKDIERFFRGYGRVNDIML--------KNGYGFVEFEDFRDADDAVY 497

Query: 80  TLNGLRLQSKTIKVSYARPSS 100
            LNG  L  + + + +AR +S
Sbjct: 496 ELNGKDLCGERVIIEHARGTS 434

 Score = 34.7 bits (78), Expect = 0.048,   Method: Compositional matrix adjust.
 Identities = 18/62 (29%), Positives = 29/62 (46%)
 Frame = -3

Query: 108 LYISGLPRTMTQKDVEDMFSRFGRIINSRVLVDQTTGLSRGVAFIRFDKRSEAEEAITSF 167
           +YI  LP    +KD+E  F  +GR+            L  G  F+ F+   +A++A+   
Sbjct: 646 VYIGRLPYQAREKDIERFFRGYGRV--------NDIMLKNGYGFVEFEDFRDADDAVYEL 491

Query: 168 NG 169
           NG
Sbjct: 490 NG 485

 Score = 28.5 bits (62), Expect = 3.7,   Method: Compositional matrix adjust.
 Identities = 19/74 (25%), Positives = 36/74 (48%), Gaps = 1/74 (1%)
 Frame = -3

Query: 243 GWCIFIYNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYEEAAMAI 302
           G  ++I  L   A E  + + F  +G V ++ +          G+GFV   ++ +A  A+
Sbjct: 655 GTRVYIGRLPYQAREKDIERFFRGYGRVNDIML--------KNGYGFVEFEDFRDADDAV 500

Query: 303 ASLNGYRL-GDKIL 315
             LNG  L G++++
Sbjct: 499 YELNGKDLCGERVI 458
>23720
          Length = 739

 Score = 37.7 bits (86), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 22/81 (27%), Positives = 37/81 (45%)
 Frame = -1

Query: 20  TNLIVNYLPQNMTQEELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAIS 79
           T + +  LP    ++++   F   G V    L          GYGFV +   +DA+ A+ 
Sbjct: 685 TRVYIGRLPYQAREKDIERFFRGYGRVNDIML--------KNGYGFVEFEDFRDADDAVY 530

Query: 80  TLNGLRLQSKTIKVSYARPSS 100
            LNG  L  + + + +AR +S
Sbjct: 529 ELNGKDLCGERVIIEHARGTS 467

 Score = 35.0 bits (79), Expect = 0.045,   Method: Compositional matrix adjust.
 Identities = 21/77 (27%), Positives = 35/77 (45%)
 Frame = -1

Query: 108 LYISGLPRTMTQKDVEDMFSRFGRIINSRVLVDQTTGLSRGVAFIRFDKRSEAEEAITSF 167
           +YI  LP    +KD+E  F  +GR+            L  G  F+ F+   +A++A+   
Sbjct: 679 VYIGRLPYQAREKDIERFFRGYGRV--------NDIMLKNGYGFVEFEDFRDADDAVYEL 524

Query: 168 NGHKPPGSSEPITVKFA 184
           NG    G  E + ++ A
Sbjct: 523 NGKDLCG--ERVIIEHA 479

 Score = 28.9 bits (63), Expect = 3.1,   Method: Compositional matrix adjust.
 Identities = 23/91 (25%), Positives = 42/91 (46%), Gaps = 9/91 (9%)
 Frame = -1

Query: 234 VNVPGNASSGWC--------IFIYNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCK 285
           V+VP   S+  C        ++I  L   A E  + + F  +G V ++ +          
Sbjct: 739 VSVPSA*SAFQCLSNRMGTRVYIGRLPYQAREKDIERFFRGYGRVNDIML--------KN 584

Query: 286 GFGFVTMTNYEEAAMAIASLNGYRL-GDKIL 315
           G+GFV   ++ +A  A+  LNG  L G++++
Sbjct: 583 GYGFVEFEDFRDADDAVYELNGKDLCGERVI 491
>28605
          Length = 697

 Score = 37.0 bits (84), Expect = 0.010,   Method: Compositional matrix adjust.
 Identities = 22/75 (29%), Positives = 35/75 (46%)
 Frame = -3

Query: 22  LIVNYLPQNMTQEELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAISTL 81
            + N      ++ EL+ LFS  G V       D +  H+  YGFV + T ++  RA+  +
Sbjct: 560 FVANLSSDETSEAELQELFSKYGNV------LDTLVHHNR-YGFVQFSTEEEGRRAVEAM 402

Query: 82  NGLRLQSKTIKVSYA 96
           NG     K +K + A
Sbjct: 401 NGYMFYRKKLKCNXA 357

 Score = 34.3 bits (77), Expect = 0.068,   Method: Compositional matrix adjust.
 Identities = 22/74 (29%), Positives = 37/74 (50%), Gaps = 1/74 (1%)
 Frame = -3

Query: 246 IFIYNLGQD-ADEGILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYEEAAMAIAS 304
           +F+ NL  D   E  L ++F  +G V +  V    + N+   +GFV  +  EE   A+ +
Sbjct: 563 VFVANLSSDETSEAELQELFSKYGNVLDTLV----HHNR---YGFVQFSTEEEGRRAVEA 405

Query: 305 LNGYRLGDKILQVS 318
           +NGY    K L+ +
Sbjct: 404 MNGYMFYRKKLKCN 363
>24794
          Length = 622

 Score = 35.8 bits (81), Expect = 0.022,   Method: Compositional matrix adjust.
 Identities = 15/40 (37%), Positives = 26/40 (65%)
 Frame = -2

Query: 65  FVNYVTAKDAERAISTLNGLRLQSKTIKVSYARPSSEVIK 104
           FV Y   +DAE+AI  ++G  +  + ++VS ARP S+ ++
Sbjct: 489 FVVYRYEEDAEKAIRRMDGESMHGRRVRVSLARPRSQGVR 370
>15503
          Length = 570

 Score = 35.4 bits (80), Expect = 0.036,   Method: Compositional matrix adjust.
 Identities = 18/62 (29%), Positives = 34/62 (54%)
 Frame = +1

Query: 108 LYISGLPRTMTQKDVEDMFSRFGRIINSRVLVDQTTGLSRGVAFIRFDKRSEAEEAITSF 167
           LY+  LP  +T +++ D+F ++G I   RV     T  ++G AF+ ++   +A+ A    
Sbjct: 154 LYVKNLPYKITAEEMYDIFGKYGAIRQIRV---GNTPETKGTAFVVYEDIFDAKNACDHL 324

Query: 168 NG 169
           +G
Sbjct: 325 SG 330

 Score = 33.5 bits (75), Expect = 0.11,   Method: Compositional matrix adjust.
 Identities = 23/92 (25%), Positives = 44/92 (47%)
 Frame = +1

Query: 228 MSGISGVNVPGNASSGWCIFIYNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCKGF 287
           MS    V +P   +    +++ NL        ++ +FG +GA+  ++V    NT + KG 
Sbjct: 106 MSKKGNVRLPPEVNR--VLYVKNLPYKITAEEMYDIFGKYGAIRQIRV---GNTPETKGT 270

Query: 288 GFVTMTNYEEAAMAIASLNGYRLGDKILQVSF 319
            FV   +  +A  A   L+G+ + ++ L V +
Sbjct: 271 AFVVYEDIFDAKNACDHLSGFNVCNRYLVVLY 366
>19733
          Length = 723

 Score = 34.7 bits (78), Expect = 0.049,   Method: Compositional matrix adjust.
 Identities = 45/209 (21%), Positives = 85/209 (40%), Gaps = 32/209 (15%)
 Frame = +3

Query: 130 GRIINSRVLVDQTTGLSRGVAFIRFDKRSEAEEAITSFNGHKPPG----SSEPITVKFAA 185
           G +   R+++D+ TG SRG AF++F ++  A++ + +       G       P+ V  A 
Sbjct: 3   GELAYVRLVIDKVTGQSRGTAFVQFKEKDAADQCLANXQDTTRGGGLRVQGRPLYVVAAV 182

Query: 186 NPNQ---------------NKNMALLSQ-LYHSPARRFGGPVHHQA-QRFRFSPMGVDHM 228
           +  Q               N+N+ L  + L  +  +   G       +R +   +  + +
Sbjct: 183 SRTQAQTQKEADKSKEQKDNRNLFLAREGLIRAGTQAAEGMSQEDINKRMKVEMVKREKL 362

Query: 229 SGISGVNVPGNASSGWCIFIYNLGQDADEGILWQMFGPF-----GAVTNVKVIRDF---- 279
             I+ + V   +S+  C  ++NL    DE  L  +           +T  +V+RD     
Sbjct: 363 KNIN-IFV---SSTRLC--VHNLLPSVDEKQLKTVVRKIVDDSTMKITECRVMRDLARTK 524

Query: 280 --NTNKCKGFGFVTMTNYEEAAMAIASLN 306
               +K  G+ FV  + +E A  A+  LN
Sbjct: 525 QSGQSKSLGYAFVNFSTHEHALKALRGLN 611

 Score = 31.6 bits (70), Expect = 0.49,   Method: Compositional matrix adjust.
 Identities = 23/77 (29%), Positives = 40/77 (51%), Gaps = 11/77 (14%)
 Frame = +3

Query: 17  IGRTNLIVNYLPQNMTQEELRSLFSSIGEVESAK---------LIRDKVAGHS--LGYGF 65
           +  T L V+ L  ++ +++L+++   I +  + K         L R K +G S  LGY F
Sbjct: 381 VSSTRLCVHNLLPSVDEKQLKTVVRKIVDDSTMKITECRVMRDLARTKQSGQSKSLGYAF 560

Query: 66  VNYVTAKDAERAISTLN 82
           VN+ T + A +A+  LN
Sbjct: 561 VNFSTHEHALKALRGLN 611
>39789
          Length = 361

 Score = 34.7 bits (78), Expect = 0.058,   Method: Compositional matrix adjust.
 Identities = 20/67 (29%), Positives = 34/67 (50%)
 Frame = +1

Query: 238 GNASSGWCIFIYNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYEE 297
            N+ S   +F+ NL  D D+   + +   F   T  ++ +  +T K +GFGFV  +  ++
Sbjct: 70  ANS*STSVLFVGNLSYDTDQ---YSLKDAFPGATAARIAKFQDTQKPRGFGFVEFSTPDD 240

Query: 298 AAMAIAS 304
           AA A  S
Sbjct: 241 AASAFDS 261
>05273
          Length = 1009

 Score = 34.3 bits (77), Expect = 0.074,   Method: Compositional matrix adjust.
 Identities = 19/53 (35%), Positives = 28/53 (52%), Gaps = 1/53 (1%)
 Frame = -1

Query: 114 PRTMTQKDVEDMFSRFGRIINSRVLVDQTTGLSRGVAFIRF-DKRSEAEEAIT 165
           P   T   + + F +FG I  + V+ D+ TG SRG  F+   D+R+  E A T
Sbjct: 175 PIITTDHSLREYFDKFGDIDEAVVITDRQTGKSRGYGFVTMADRRARTEPART 17

 Score = 33.9 bits (76), Expect = 0.088,   Method: Compositional matrix adjust.
 Identities = 15/35 (42%), Positives = 20/35 (57%)
 Frame = -1

Query: 260 LWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTN 294
           L + F  FG +    VI D  T K +G+GFVTM +
Sbjct: 151 LREYFDKFGDIDEAVVITDRQTGKSRGYGFVTMAD 47
>12096
          Length = 1585

 Score = 33.9 bits (76), Expect = 0.094,   Method: Compositional matrix adjust.
 Identities = 18/65 (27%), Positives = 29/65 (44%)
 Frame = -3

Query: 106  ANLYISGLPRTMTQKDVEDMFSRFGRIINSRVLVDQTTGLSRGVAFIRFDKRSEAEEAIT 165
            A + + GL  T+ + D+     R G        + + TG SRG  F+ F  +SEA+  + 
Sbjct: 1223 ATILLRGLSNTLVENDIIQELIRIGMPPKDVRFMRRVTGASRGFGFVEFQSQSEAQRWMD 1044

Query: 166  SFNGH 170
               G 
Sbjct: 1043 HNQGQ 1029
>03856
          Length = 1292

 Score = 32.7 bits (73), Expect = 0.19,   Method: Compositional matrix adjust.
 Identities = 18/68 (26%), Positives = 34/68 (50%)
 Frame = +1

Query: 30   NMTQEELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAISTLNGLRLQSK 89
             + ++EL  LF    E+     ++D +    +GY F  + T +  + A +   G R+QS 
Sbjct: 970  ELKEQELYKLFPKAQEITVPVRMKDNL---PIGYAFATFATPEQCKDAHNKGQGARVQSY 1140

Query: 90   TIKVSYAR 97
            ++ V YA+
Sbjct: 1141 SLVVLYAK 1164
>11126
          Length = 1061

 Score = 32.7 bits (73), Expect = 0.20,   Method: Compositional matrix adjust.
 Identities = 24/92 (26%), Positives = 37/92 (40%)
 Frame = -3

Query: 6   EDHMAEDCRDDIGRTNLIVNYLPQNMTQEELRSLFSSIGEVESAKLIRDKVAGHSLGYGF 65
           ED +  D R      ++ V  +    T EEL   F   G V    ++ DK +GH  G+ +
Sbjct: 654 EDKIEADLR------SVYVGNVDYGATAEELEQHFHGCGSVNRVTILCDKYSGHPKGFAY 493

Query: 66  VNYVTAKDAERAISTLNGLRLQSKTIKVSYAR 97
           V +        A  T      + + IKV+  R
Sbjct: 492 VEFADKDSVVTAKCTGMDSLFRGRQIKVTPKR 397
>33504
          Length = 282

 Score = 32.3 bits (72), Expect = 0.27,   Method: Composition-based stats.
 Identities = 14/41 (34%), Positives = 26/41 (63%)
 Frame = +1

Query: 101 EVIKDANLYISGLPRTMTQKDVEDMFSRFGRIINSRVLVDQ 141
           E    A ++I GLP  +T+ D+  +FS++G I+N  ++ D+
Sbjct: 154 EYKDSAWVFIGGLPYDLTEGDIICVFSQYGEIVNINLVRDK 276

 Score = 28.9 bits (63), Expect = 3.0,   Method: Composition-based stats.
 Identities = 11/29 (37%), Positives = 20/29 (68%)
 Frame = +1

Query: 27  LPQNMTQEELRSLFSSIGEVESAKLIRDK 55
           LP ++T+ ++  +FS  GE+ +  L+RDK
Sbjct: 190 LPYDLTEGDIICVFSQYGEIVNINLVRDK 276

 Score = 28.9 bits (63), Expect = 3.1,   Method: Composition-based stats.
 Identities = 13/37 (35%), Positives = 21/37 (56%)
 Frame = +1

Query: 242 SGWCIFIYNLGQDADEGILWQMFGPFGAVTNVKVIRD 278
           S W +FI  L  D  EG +  +F  +G + N+ ++RD
Sbjct: 166 SAW-VFIGGLPYDLTEGDIICVFSQYGEIVNINLVRD 273
>25950
          Length = 417

 Score = 32.0 bits (71), Expect = 0.32,   Method: Compositional matrix adjust.
 Identities = 20/99 (20%), Positives = 45/99 (45%)
 Frame = -2

Query: 14  RDDIGRTNLIVNYLPQNMTQEELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKD 73
           + +I   ++ V  +    + EEL + F   G +    ++ +K  GH  G+ ++ + + + 
Sbjct: 299 KQEIDTRSVYVGNVDYGASAEELEAHFHGCGTINRVTILCNKADGHPKGFAYIEFGSKEY 120

Query: 74  AERAISTLNGLRLQSKTIKVSYARPSSEVIKDANLYISG 112
            E A++ +N    + + IKV   R +   +   N +  G
Sbjct: 119 VETALA-MNETLFRGRQIKVMTKRTNRPGLSTTNRFARG 6
>25746
          Length = 475

 Score = 31.6 bits (70), Expect = 0.52,   Method: Compositional matrix adjust.
 Identities = 12/40 (30%), Positives = 25/40 (62%)
 Frame = +1

Query: 94  SYARPSSEVIKDANLYISGLPRTMTQKDVEDMFSRFGRII 133
           SY+    +  K  ++Y+SGLP  +T +  +++ S++G I+
Sbjct: 37  SYSWFDMDTEKSTHVYVSGLPSDLTDEQFQELMSKYGLIM 156
>00781
          Length = 3170

 Score = 31.2 bits (69), Expect = 0.54,   Method: Compositional matrix adjust.
 Identities = 24/91 (26%), Positives = 42/91 (46%)
 Frame = -1

Query: 108  LYISGLPRTMTQKDVEDMFSRFGRIINSRVLVDQTTGLSRGVAFIRFDKRSEAEEAITSF 167
            +Y+ G  +  +++ +  MFS+ G +    +   +TT   +G AF+ F    EA +A+   
Sbjct: 2714 VYVEGFHKFTSREWISRMFSKCGTVTYVSLPCFKTTREIKGYAFVEFQSPEEAVKAVQML 2535

Query: 168  NGHKPPGSSEPITVKFAANPNQNKNMALLSQ 198
            N   P    E    K  A   Q KN+ +L +
Sbjct: 2534 N-RVPEQLDEKSEEKSLACIKQCKNLTILKK 2445

 Score = 30.8 bits (68), Expect = 0.87,   Method: Compositional matrix adjust.
 Identities = 18/48 (37%), Positives = 24/48 (50%), Gaps = 2/48 (4%)
 Frame = -1

Query: 261  W--QMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYEEAAMAIASLN 306
            W  +MF   G VT V +     T + KG+ FV   + EEA  A+  LN
Sbjct: 2675 WISRMFSKCGTVTYVSLPCFKTTREIKGYAFVEFQSPEEAVKAVQMLN 2532
>29364
          Length = 1126

 Score = 31.2 bits (69), Expect = 0.66,   Method: Compositional matrix adjust.
 Identities = 15/39 (38%), Positives = 23/39 (58%)
 Frame = +1

Query: 62  GYGFVNYVTAKDAERAISTLNGLRLQSKTIKVSYARPSS 100
           GYGFV +   +DA+ A+  LNG  L  + + V  AR ++
Sbjct: 70  GYGFVEFEDYRDADDAVYELNGKELLGERVVVEPARGTA 186
>11579
          Length = 1307

 Score = 30.8 bits (68), Expect = 0.76,   Method: Compositional matrix adjust.
 Identities = 13/24 (54%), Positives = 18/24 (75%)
 Frame = +3

Query: 146 SRGVAFIRFDKRSEAEEAITSFNG 169
           SRG AF+RF  R +AE+A+ S +G
Sbjct: 3   SRGFAFVRFYDRRDAEDAMDSMDG 74
>28372
          Length = 398

 Score = 30.4 bits (67), Expect = 0.98,   Method: Compositional matrix adjust.
 Identities = 12/32 (37%), Positives = 21/32 (65%)
 Frame = -2

Query: 62  GYGFVNYVTAKDAERAISTLNGLRLQSKTIKV 93
           G+GFV +  + +AERA   +NG  ++ + I+V
Sbjct: 256 GFGFVTFAHSAEAERARDKMNGTVVEGRKIEV 161
>02077
          Length = 1219

 Score = 29.3 bits (64), Expect = 2.1,   Method: Compositional matrix adjust.
 Identities = 19/73 (26%), Positives = 32/73 (43%), Gaps = 1/73 (1%)
 Frame = +2

Query: 181 VKFAANPNQNKNMALLSQLYHSPARRFGGPVHHQAQRFRF-SPMGVDHMSGISGVNVPGN 239
           +K +     NK   L++ L  +PAR     +H + Q  +  S   +     ++  N P  
Sbjct: 797 LKKSCGKKSNKTNVLMTLLKINPARHAKITIHMRKQETQT*SYTNISFHRPVASKNAPKY 976

Query: 240 ASSGWCIFIYNLG 252
           A+ G+C FI   G
Sbjct: 977 ANGGFCTFIQQCG 1015
>19556
          Length = 917

 Score = 29.3 bits (64), Expect = 2.2,   Method: Compositional matrix adjust.
 Identities = 19/68 (27%), Positives = 38/68 (55%), Gaps = 2/68 (2%)
 Frame = -1

Query: 109 YISGLPRTMTQKDVEDMFSRFGRIINSRVLVDQTTGL-SRGVAFIRFDKRSEA-EEAITS 166
           +I GL + +T++++ + FSRFG++ N  +   +T G+ SR  A++         ++  T+
Sbjct: 821 FIGGLVKGVTEEELMEKFSRFGQVSNVDIKT-RTNGIDSRTFAYVNLTAEENGFKKCFTA 645

Query: 167 FNGHKPPG 174
           +N  K  G
Sbjct: 644 YNNTKWKG 621

 Score = 28.9 bits (63), Expect = 3.4,   Method: Compositional matrix adjust.
 Identities = 22/89 (24%), Positives = 43/89 (48%), Gaps = 2/89 (2%)
 Frame = -1

Query: 14  RDDIGRTNLIVNYLPQNMTQEELRSLFSSIGEVESAKLIRDKVAG-HSLGYGFVNYVTAK 72
           R  + R    +  L + +T+EEL   FS  G+V +   I+ +  G  S  + +VN    +
Sbjct: 848 RWQLQRKENFIGGLVKGVTEEELMEKFSRFGQVSNVD-IKTRTNGIDSRTFAYVNLTAEE 672

Query: 73  DA-ERAISTLNGLRLQSKTIKVSYARPSS 100
           +  ++  +  N  + +   +K+ YA+ SS
Sbjct: 671 NGFKKCFTAYNNTKWKGGQLKLQYAKESS 585
>09947
          Length = 860

 Score = 29.3 bits (64), Expect = 2.5,   Method: Compositional matrix adjust.
 Identities = 9/38 (23%), Positives = 20/38 (52%)
 Frame = -1

Query: 241 SSGWCIFIYNLGQDADEGILWQMFGPFGAVTNVKVIRD 278
           S GWCI++ ++G D+    ++++  P   +     + D
Sbjct: 707 SGGWCIYVADIGSDSSTHTIYKIREPLDLINQTLEVED 594
>17175
          Length = 512

 Score = 28.1 bits (61), Expect = 4.6,   Method: Compositional matrix adjust.
 Identities = 12/33 (36%), Positives = 17/33 (51%)
 Frame = -3

Query: 16  DIGRTNLIVNYLPQNMTQEELRSLFSSIGEVES 48
           D     + V  +P+NM + ELR +F   G V S
Sbjct: 102 DADSIKMFVGQIPRNMDENELRKMFEDYGPVHS 4
>32930
          Length = 901

 Score = 28.1 bits (61), Expect = 5.4,   Method: Compositional matrix adjust.
 Identities = 18/79 (22%), Positives = 38/79 (48%), Gaps = 2/79 (2%)
 Frame = -3

Query: 99  SSEVIKDANLYISGL--PRTMTQKDVEDMFSRFGRIINSRVLVDQTTGLSRGVAFIRFDK 156
           ++E++K+   +   L   + +T+ D++D+     ++  +     + T L  G+       
Sbjct: 383 TTEIVKEVKHFYEXLYSKKQITEGDIKDLVEXIPKLTPT-----ERTSLEGGITL----- 234

Query: 157 RSEAEEAITSFNGHKPPGS 175
            SEA EA+ S   +K PG+
Sbjct: 233 -SEANEALKSMKNNKSPGT 180
>05987
          Length = 1726

 Score = 27.3 bits (59), Expect = 9.8,   Method: Compositional matrix adjust.
 Identities = 18/63 (28%), Positives = 28/63 (44%)
 Frame = -2

Query: 35  ELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAISTLNGLRLQSKTIKVS 94
           +L  LF    E+   K  +D      +GY F  +VT +  + A     G +LQ   + V 
Sbjct: 831 DLFKLFPKAQEIVIPKRKKD---NKPVGYAFAVFVTDEQCKTAFHKNQGAKLQGHNLVVL 661

Query: 95  YAR 97
           YA+
Sbjct: 660 YAK 652
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|7106303|ref|NP_034249.1| EH-domain containing 1 [Mus
musculus]
         (534 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

28292                                                                 228   3e-60
19303                                                                 149   6e-52
01130                                                                  71   1e-12
01021                                                                  36   0.033
20290                                                                  31   1.6  
14601                                                                  30   2.3  
33913                                                                  30   2.3  
14189                                                                  30   3.3  
18248                                                                  28   8.1  
>28292
          Length = 1324

 Score =  228 bits (582), Expect = 3e-60,   Method: Compositional matrix adjust.
 Identities = 133/370 (35%), Positives = 197/370 (53%), Gaps = 12/370 (3%)
 Frame = -3

Query: 17   LFQTVAEGLRQLYAQKLLPLEEHYRFHEFHSPALEDADFDNKPMVLLVGQYSTGKTTFIR 76
            + +   + L ++Y + + PLE+ YRF + +  A+ + +   KPM+L +G +STGK+T I 
Sbjct: 1229 VLEAAQQRLLEIYKENIQPLEQAYRFADLNRDAISEGEMLAKPMILFLGPWSTGKSTMIN 1050

Query: 77   HLI--EQDFPGMRIGPEPTTDSFIAVMHGPTEGVVPGNALVVDPRRPFRKLNAFGNAFLN 134
            +++  EQ    +  G EPTT  F  V +G T  +V G  LV D  + +  L  FG  FL 
Sbjct: 1049 YILKNEQANWKLHTGAEPTTSDFTMVTYGITARMVKGIQLVSDKTKHYTPLQKFGLNFLE 870

Query: 135  RFMCAQLPNPVLDSISIIDTPGILSGEKQRISRGYDFAAVLEWFAERVDRIILLFDAHKL 194
            RF   +LP P+L  ++++DTPGI+  +KQ+  RGY F  V +WF +R   I L+FD  KL
Sbjct: 869  RFQGMELPAPLLKQVTLVDTPGIIENKKQQ-ERGYPFNDVCQWFIDRAQLIFLVFDPSKL 693

Query: 195  DISDEFSEVIKALKNHEDKIRVVLNKADQIETQQLMRVYGALMWSLGKIINTPEVVRVYI 254
            DI  E   + + LK HE K+R++LNKAD + TQ+LMRVYGAL WSL  +IN  E  RVY+
Sbjct: 692  DIGSELEMLFRQLKGHEAKLRLILNKADTVTTQELMRVYGALFWSLAPLINLVEPPRVYV 513

Query: 255  GSFWSHPLLIPDNRKLFEAEEQDLFKDIQSLPRNAALRKLNDLIKRARLAKVHAYIISSL 314
            GS WS          LFE EE  L  D+Q + R     K+    + A L ++HA    S+
Sbjct: 512  GSMWSQSYQPTTMHTLFEEEETSLSMDLQQVIRYQLEYKIAATRRHAFLVRLHAL---SV 342

Query: 315  KKEMPNVFGKESKKKELVNNLGE----------IYQKIEREHQISSGDFPSLRKMQELLQ 364
             K +     K      ++ N G           I +++ +   +S  D P+    Q + Q
Sbjct: 341  DKYLSVFTDKRG*YLVIMINCGRKLSPLP*KFFIPEQLMQHEDVSIHDLPTAEMYQLVFQ 162

Query: 365  TQDFSKFQAL 374
             +   K QA 
Sbjct: 161  VEQSVKVQAF 132
>19303
          Length = 676

 Score =  149 bits (377), Expect(2) = 6e-52,   Method: Compositional matrix adjust.
 Identities = 67/94 (71%), Positives = 83/94 (88%)
 Frame = -1

Query: 438 EWVVGKDKPTYDEIFYTLSPVNGKITGANAKKEMVKSKLPNTVLGKIWKLADVDKDGLLD 497
           EWVV ++K  YD+ F  L+P+NGK++GA AK EMVKSKLPN+VL K+WKLADVDKDG+LD
Sbjct: 418 EWVVSREKYEYDDSFSKLNPINGKVSGAAAKSEMVKSKLPNSVLSKVWKLADVDKDGMLD 239

Query: 498 DEEFALANHLIKVKLEGHELPADLPPHLIPPSKR 531
            +E+ALANHLIK+KLEGH+LP+DLP HL+PPSKR
Sbjct: 238 ADEWALANHLIKIKLEGHDLPSDLPSHLVPPSKR 137

 Score = 73.6 bits (179), Expect(2) = 6e-52,   Method: Compositional matrix adjust.
 Identities = 37/63 (58%), Positives = 47/63 (74%), Gaps = 2/63 (3%)
 Frame = -2

Query: 356 LRKMQELLQTQDFSKFQALKPKLLDTVDDMLANDIARLMVMV--RQEESLMPSQAVKGGA 413
           L++MQE L   DF+KF A+KPKLL+TVD+MLANDIARLM M+    E+      AV+GGA
Sbjct: 672 LKRMQEQLAFHDFTKFHAIKPKLLETVDNMLANDIARLMQMIPLEDEDQSNGQAAVQGGA 493

Query: 414 FDG 416
           F+G
Sbjct: 492 FEG 484
>01130
          Length = 1032

 Score = 70.9 bits (172), Expect = 1e-12,   Method: Compositional matrix adjust.
 Identities = 39/96 (40%), Positives = 53/96 (55%), Gaps = 2/96 (2%)
 Frame = +3

Query: 435 DDVEWVVGKD--KPTYDEIFYTLSPVNGKITGANAKKEMVKSKLPNTVLGKIWKLADVDK 492
           D  EW V  D  +  Y+ +FY+  PV+G I G   +   +KS L   VL +IW LADV  
Sbjct: 198 DGTEWPVVSDEERQLYELLFYSQGPVDGYILGEGVRDLFLKSGLSLRVLSQIWNLADVSN 377

Query: 493 DGLLDDEEFALANHLIKVKLEGHELPADLPPHLIPP 528
           D +L+  EF+L  HLI+   +G + P  LP  L PP
Sbjct: 378 DNVLNVHEFSLVMHLIRGLHKGLKAPPTLPRKLTPP 485

 Score = 48.1 bits (113), Expect = 9e-06,   Method: Compositional matrix adjust.
 Identities = 32/101 (31%), Positives = 50/101 (49%), Gaps = 12/101 (11%)
 Frame = +3

Query: 444 DKPTYDEIFYTLSPVNGK--ITGANAKKEMVKSKLPNTVLGKIWKLADVDKDGLLDDEEF 501
           ++  Y ++F  L  V GK  + G   +     S+L + VL  +W L+DV +DG LD +EF
Sbjct: 525 EREAYIKLFRALD-VQGKGFLDGDCCRHVFEASELTSDVLSDVWNLSDVTRDGKLDVDEF 701

Query: 502 ALANHLIKVKLEGH----------ELPADLPPHLIPPSKRR 532
            +A HL++    G+          ELP  + P  +   KRR
Sbjct: 702 CVACHLLRFVKAGNSLSGPVDVFTELPDKVAPQSLRARKRR 824
>01021
          Length = 2238

 Score = 36.2 bits (82), Expect = 0.033,   Method: Compositional matrix adjust.
 Identities = 19/76 (25%), Positives = 39/76 (51%), Gaps = 1/76 (1%)
 Frame = +2

Query: 149 ISIIDTPGILSGEKQRISRGYDFAAVLEWFAERVDRIILLFDAHKLDISDEFSEVIKAL- 207
           ++ +DTPG++ G+   +   +D    + W  +  D I + FD     +      +++ L 
Sbjct: 392 VTFVDTPGLVDGD---MKYPFDVNKSILWLGDLADLIFIFFDPIGQALCKRTLNLVEKLN 562

Query: 208 KNHEDKIRVVLNKADQ 223
           + H D++R  L+KAD+
Sbjct: 563 EKHADRMRFYLSKADE 610
>20290
          Length = 1550

 Score = 30.8 bits (68), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 16/51 (31%), Positives = 27/51 (52%), Gaps = 7/51 (13%)
 Frame = +1

Query: 49  ALEDADFDNKPMVLLVGQYSTGKTTFIRHLI-------EQDFPGMRIGPEP 92
            ++   F +  +++L+G+  TGKTTFIR L        E + P + I  +P
Sbjct: 751 TVQQGHFSDSEILVLLGENGTGKTTFIRMLAGNLQPDGEVELPMLNISYKP 903
>14601
          Length = 472

 Score = 30.0 bits (66), Expect = 2.3,   Method: Compositional matrix adjust.
 Identities = 12/29 (41%), Positives = 19/29 (65%)
 Frame = +3

Query: 478 NTVLGKIWKLADVDKDGLLDDEEFALANH 506
           +TV+ +I++  D DKDG +  EEF+   H
Sbjct: 135 STVVSQIFEHEDKDKDGFISHEEFSGPKH 221
>33913
          Length = 1202

 Score = 30.0 bits (66), Expect = 2.3,   Method: Compositional matrix adjust.
 Identities = 20/77 (25%), Positives = 39/77 (50%)
 Frame = +1

Query: 267 NRKLFEAEEQDLFKDIQSLPRNAALRKLNDLIKRARLAKVHAYIISSLKKEMPNVFGKES 326
           NR L E   QDL + I +LPR+AA +   D ++      V     + L+K +   +G  +
Sbjct: 715 NRDLAELPTQDLIRAISTLPRDAAWKA--DHLQTIERLLVKRLYNTPLEKCLQACYGFYN 888

Query: 327 KKKELVNNLGEIYQKIE 343
           ++  LV  + +++  ++
Sbjct: 889 QEHYLVPFVSQMFSVVD 939
>14189
          Length = 430

 Score = 29.6 bits (65), Expect = 3.3,   Method: Composition-based stats.
 Identities = 13/34 (38%), Positives = 23/34 (67%)
 Frame = +2

Query: 487 LADVDKDGLLDDEEFALANHLIKVKLEGHELPAD 520
           +A+V +D L+DDEE     +L+ ++ EG + PA+
Sbjct: 17  IAEVPEDALIDDEEIVDEENLLAMEEEGEQQPAE 118
>18248
          Length = 466

 Score = 28.1 bits (61), Expect = 8.1,   Method: Compositional matrix adjust.
 Identities = 10/30 (33%), Positives = 20/30 (66%)
 Frame = +3

Query: 49  ALEDADFDNKPMVLLVGQYSTGKTTFIRHL 78
            +   +F +  +++++G+  TGKTTFI+ L
Sbjct: 72  TVHPGEFTDSEIIVMLGENGTGKTTFIKML 161
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|126521835|ref|NP_031662.2| chaperonin subunit 2
(beta) [Mus musculus]
         (535 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

01159                                                                 228   4e-60
30661                                                                 196   2e-50
09900                                                                 148   6e-36
12796                                                                 142   3e-34
06409                                                                 137   2e-32
05356                                                                 108   6e-24
29864                                                                  89   6e-18
29631                                                                  84   2e-16
33770                                                                  79   6e-15
17249                                                                  57   1e-08
>01159
          Length = 2613

 Score =  228 bits (582), Expect = 4e-60,   Method: Compositional matrix adjust.
 Identities = 159/505 (31%), Positives = 264/505 (52%), Gaps = 8/505 (1%)
 Frame = +3

Query: 24  ARLSSFIGAIAIGDLVKSTLGPKGMDKILLSSGRDAALMVTNDGATILKNIGVDNPAAKV 83
           A  S  + A ++  ++K++LGPKG+DK+++S   D  + VTNDGATIL  + VD+  AK+
Sbjct: 189 AHKSHILAAKSVASILKTSLGPKGLDKMMVSG--DGDVTVTNDGATILDMMDVDHQIAKL 362

Query: 84  LVDMSRVQDDEVGDGTTSVTVXXXXXXXXXXSLIAKKIHPQTIISGWREATKAAREALLS 143
           +V +S+ QDDE+GDGTT V V           L+ + IHP  I  G+  A K A E L  
Sbjct: 363 MVQLSKSQDDEIGDGTTGVVVLAGALLEQAEKLLDRGIHPIRIADGYEIAAKCAVETL-D 539

Query: 144 SAVDHGSDEARFWQDLMNIAGTTLSSKLLTHHKDHFTKLAVEAVLRL----KGSGNLEAI 199
              D+   + +  + L+ +A TTL SK++        K+AV+A++ +    +   + E I
Sbjct: 540 KISDNYEVDLKNAEPLIKLAMTTLGSKIVNRCHRQMAKIAVDAIMSVADLKRKDVDFELI 719

Query: 200 HVIKKLGGSLADSYLDEGFLLDKKIGVNQ-PKRIENAKILIANTGMDTDKIKIFGSRVRV 258
            V  K+GG L D+ L +G ++DK +   Q PK +++AKI I     +  K K    ++ +
Sbjct: 720 KVEGKVGGKLEDTMLVKGVVVDKDMSHPQMPKVVKDAKIAILTCPFEPPKPKT-KHKLDI 896

Query: 259 DSTAKVAEIEHAEKEKMKEKVERILKHGINCFINRQLIYNYPEQLFGAAGVMAIEHADFA 318
            S     ++   E  K +  V+ +   G N  I +    +    L     + A+      
Sbjct: 897 TSVEDYKKLREYELNKFESMVQSVKDKGANLVICQWGFDDEANHLLLQRELPAVRWVGGP 1076

Query: 319 GVERLALVTGGEIASTFDHPELVKLGSCKLIEEVMIG--EDKLIHFSGVALGEACTIVLR 376
            +E +A+ TGG I   F+     KLG   ++ E+  G  +D+++         A TI +R
Sbjct: 1077EIELIAIATGGRIVPRFEELTTEKLGKAGIVRELTFGTTKDRMLVIEECLNTRAVTIFIR 1256

Query: 377 GATQQILDEAERSLHDALCVLAQTVKDPRTVYGGGCSEMLMAHAVTQLANRTPGKEAVAM 436
           G  + I++EA+RSLHDALCV+   V+D R VYGGG  E+  + AV + A++    E  A+
Sbjct: 1257GGNKMIVEEAKRSLHDALCVIRNLVRDNRVVYGGGAPEIAASVAVAEAADKISTLEQYAV 1436

Query: 437 ESFAKALRMLPTIIADNAGYDSADLVAQLRAAH-SEGHITAGLDMKEGTIGDMAVLGITE 495
            SF++AL  +P  +A+N+G      +A++++    E +   G+D       DM    + E
Sbjct: 1437RSFSEALEAVPLALAENSGLAPIQTLAEVKSRQVKEKNPRLGIDCLLKGTNDMKEQNVIE 1616

Query: 496 SFQVKRQVLLSAAEAAEVILRVDNI 520
           +   K+Q +L A +   +IL++D+I
Sbjct: 1617TLTAKKQQILLATQLVRMILKIDDI 1691
>30661
          Length = 380

 Score =  196 bits (498), Expect = 2e-50,   Method: Compositional matrix adjust.
 Identities = 94/112 (83%), Positives = 100/112 (89%)
 Frame = +3

Query: 328 GGEIASTFDHPELVKLGSCKLIEEVMIGEDKLIHFSGVALGEACTIVLRGATQQILDEAE 387
           GGEI STFD PE  KLG C LIEEVMIGEDKLI FSGVALGEACTIVLRGATQQILDEA 
Sbjct: 30  GGEITSTFDCPEKTKLGQCDLIEEVMIGEDKLIKFSGVALGEACTIVLRGATQQILDEAX 209

Query: 388 RSLHDALCVLAQTVKDPRTVYGGGCSEMLMAHAVTQLANRTPGKEAVAMESF 439
           RSLHDALCVL+QTVK+ RTVYGGGCSEMLMA AV+QLA +TPGKEA+AME+ 
Sbjct: 210 RSLHDALCVLSQTVKETRTVYGGGCSEMLMAEAVSQLAAKTPGKEAIAMEAL 365
>09900
          Length = 1305

 Score =  148 bits (373), Expect = 6e-36,   Method: Compositional matrix adjust.
 Identities = 85/273 (31%), Positives = 147/273 (53%)
 Frame = +3

Query: 254 SRVRVDSTAKVAEIEHAEKEKMKEKVERILKHGINCFINRQLIYNYPEQLFGAAGVMAIE 313
           + VRVD+  +   I  AE + + +K+++I + G    +++  I +   Q F    +    
Sbjct: 111 AEVRVDNVQEYQSIVDAEWKILYDKLDKIHQSGAKVVLSKLPIGDVATQYFADRDMFCAG 290

Query: 314 HADFAGVERLALVTGGEIASTFDHPELVKLGSCKLIEEVMIGEDKLIHFSGVALGEACTI 373
                 + R     GG I +T        LG+C+L +E+ IG ++   F G  +   CTI
Sbjct: 291 RVPEEDLRRTMKACGGSIQTTVQSLTPDVLGTCQLFDEIQIGGERFNMFKGCTMARTCTI 470

Query: 374 VLRGATQQILDEAERSLHDALCVLAQTVKDPRTVYGGGCSEMLMAHAVTQLANRTPGKEA 433
           +LRG  +Q ++E ERSLHDA+ ++ + +K+   V GGG  EM +++ + + ++   GKE 
Sbjct: 471 ILRGGAEQFMEETERSLHDAIMIVRRAIKNDSVVAGGGAIEMEVSYHLREHSHTIAGKEQ 650

Query: 434 VAMESFAKALRMLPTIIADNAGYDSADLVAQLRAAHSEGHITAGLDMKEGTIGDMAVLGI 493
           + M ++AKAL ++P  + DNAG+D+ +++ +LR  H++G    G+++    I D     +
Sbjct: 651 LLMSAYAKALEVIPRQLCDNAGFDATNILNKLRQKHAQGGTWYGVNILREDIADNFEDCV 830

Query: 494 TESFQVKRQVLLSAAEAAEVILRVDNIIKAAPR 526
            E   VK   L +A+EA  +IL VD  IK  PR
Sbjct: 831 WEPAVVKINALTAASEATALILSVDETIK-NPR 926
>12796
          Length = 1316

 Score =  142 bits (358), Expect = 3e-34,   Method: Compositional matrix adjust.
 Identities = 96/336 (28%), Positives = 166/336 (49%), Gaps = 7/336 (2%)
 Frame = -3

Query: 193  SGNLEAIHVIKKLGGSLADSYLDEGFLL-DKKIGVNQPKRIENAKILIANTGMDTDKIKI 251
            S +L+ I VI+ LGG++ D+ L  G +   +  G N PKRIE AKI +    +   K  +
Sbjct: 1311 SVDLKNIKVIRSLGGTVEDTELVNGLVFTSRSAGTNAPKRIEKAKIGLIQFCISAPKTDM 1132

Query: 252  FGSRVRVDSTAKVAEIEHAEKEKMKEKVERILKHGINCF-----INRQLIYNYPEQLFGA 306
                V V   A +  +   E+  +   V++I K G N       I R  + +  +     
Sbjct: 1131 -DHNVIVSDYAAMDRVLKEERSYILNIVKQIKKAGCNVLLVQKSILRDAVSDLAQHFLDK 955

Query: 307  AGVMAIEHADFAGVERLALVTGGEIASTFDHPELVKLGSCKLIEEVMIGEDKLIHFSGVA 366
               + ++  +   +E +         ++ DH     + S  L+EEV  G +K +  +G+ 
Sbjct: 954  IKCLVVKDVEREDIEFVCKTLHCRPIASLDHFTAENMSSADLVEEVASGTNKFVKITGIQ 775

Query: 367  -LGEACTIVLRGATQQILDEAERSLHDALCVLAQTVKDPRTVYGGGCSEMLMAHAVTQLA 425
              G   +I+ RG+ + +L+EA RSLHDALCV+   V++   + GGG  E+ MA  +   A
Sbjct: 774  NQGRTVSIICRGSNKLVLEEAARSLHDALCVVRCLVRNRAQIVGGGAPEIEMALQLAAAA 595

Query: 426  NRTPGKEAVAMESFAKALRMLPTIIADNAGYDSADLVAQLRAAHSEGHITAGLDMKEGTI 485
                G +A    +FA AL ++P+ +A+NAG +    V +LR  H++G   AG+++++G I
Sbjct: 594  QTVDGVDAYCYRAFADALEVIPSTLAENAGLNPIATVTELRNRHAQGEKNAGINVRKGAI 415

Query: 486  GDMAVLGITESFQVKRQVLLSAAEAAEVILRVDNII 521
             D+    + +   V    +  A E    IL++D+I+
Sbjct: 414  TDIFAENVVQPLLVSTSAITLATETVRSILKIDDIV 307
>06409
          Length = 1533

 Score =  137 bits (344), Expect = 2e-32,   Method: Compositional matrix adjust.
 Identities = 90/307 (29%), Positives = 154/307 (50%), Gaps = 8/307 (2%)
 Frame = -3

Query: 225  GVNQPKRIENAKILIANTGMDTDKIKIFGSRVRVDSTAKVAEIEHAEKEKMKEKVERILK 284
            G   P ++E AKI      +   K  +  ++V V    ++  +   E+  + + V++I K
Sbjct: 1513 GAGGPSKVEKAKIGFIQFCISPPKTDM-ENQVIVSDYTQMDRVLREERNYILDIVKKIKK 1337

Query: 285  HGINCF-----INRQLIYNYPEQLFGAAGVMAIEHADFAGVERLALVTGGEIASTFDH-- 337
             G N       I R  + +          +M ++  +   VE +    G    ++ DH  
Sbjct: 1336 AGCNVLLIQKSILRDAVSDLALHFLAKMKIMVVKDIEREDVEFVCKTLGCRPVASLDHFL 1157

Query: 338  PELVKLGSCKLIEEVMIGEDKLIHFSGVA-LGEACTIVLRGATQQILDEAERSLHDALCV 396
            PE   LGS  LIEEV  G  K++  +G+A  G+  T+++RG+ + +L+EA+RSLHDALCV
Sbjct: 1156 PE--NLGSADLIEEVQTGSSKIVKATGIANPGQTVTVLIRGSNKLVLEEADRSLHDALCV 983

Query: 397  LAQTVKDPRTVYGGGCSEMLMAHAVTQLANRTPGKEAVAMESFAKALRMLPTIIADNAGY 456
            +   VK    + GGG  E  M+  +   AN   G E     +FA+AL ++P  +A+NAG 
Sbjct: 982  IRCLVKKKALIAGGGAPETEMSMRLAAYANTLAGMEQYCFRAFAEALEVIPFTLAENAGL 803

Query: 457  DSADLVAQLRAAHSEGHITAGLDMKEGTIGDMAVLGITESFQVKRQVLLSAAEAAEVILR 516
            +    V  LR  H++G  TAG+++++G I ++    + +   V    +  A+E    IL+
Sbjct: 802  NPISTVTXLRTRHAQGERTAGINVRKGAITNILEENVLQPLLVSTSAITLASETVRSILK 623

Query: 517  VDNIIKA 523
            +D+I+  
Sbjct: 622  IDDIVNC 602
>05356
          Length = 2339

 Score =  108 bits (270), Expect = 6e-24,   Method: Compositional matrix adjust.
 Identities = 64/190 (33%), Positives = 103/190 (54%), Gaps = 2/190 (1%)
 Frame = +1

Query: 338  PELVKLGSCKLIEEVMIGEDKLIHFS-GVALGEACTIVLRGATQQILDEAERSLHDALCV 396
            P   + G C L+    IGE  ++ F          T+++RG+T  I+D+ ER+L D +  
Sbjct: 1204 PRNEECGYCDLVYVDEIGETPVVIFQQNKDESPITTVIIRGSTDNIMDDIERALDDGVNT 1383

Query: 397  LAQTVKDPRTVYGGGCSEMLMAHAVTQLANRTPGKEAVAMESFAKALRMLPTIIADNAGY 456
                 KD R V G G +E+ +A  +T      PG E  A++ FA++L ++P  +A+N G 
Sbjct: 1384 FKALTKDDRLVPGAGATEIELAKQITTYGESLPGLEQYAVKKFAESLEVIPRALAENTGM 1563

Query: 457  DSADLVAQLRAAHSEGHITAGLDMKE-GTIGDMAVLGITESFQVKRQVLLSAAEAAEVIL 515
             + D++++L AAH EG   AG+D+ + G++ D     +T+ +  +   L  AA AA  +L
Sbjct: 1564 KATDILSKLYAAHQEGQQNAGVDIDDSGSVLDAKQANLTDLYLNRYWGLKFAAAAACTVL 1743

Query: 516  RVDNIIKAAP 525
            RVD II A P
Sbjct: 1744 RVDQIIMAKP 1773

 Score = 80.1 bits (196), Expect = 2e-15,   Method: Compositional matrix adjust.
 Identities = 68/255 (26%), Positives = 126/255 (49%), Gaps = 3/255 (1%)
 Frame = +2

Query: 40  KSTLGPKGMDKILLSSGRDAALMVTNDGATILKNIGVDNPAAKVLVDMSRVQDDEVGDGT 99
           +S  GP G +K++++      L VTND ATIL+ + V +PAAK+LV  +  Q+ E GDGT
Sbjct: 320 RSAYGPHGQNKMVINHLEK--LFVTNDAATILRELEVQHPAAKMLVLAAHQQEQECGDGT 493

Query: 100 TSVTVXXXXXXXXXXSLIAKKIHPQTIISGWREATKAAREALLSSAVDHGSDEARFWQDL 159
             V V           L+   +    +I G+  A K A E L    + H  +  R  +++
Sbjct: 494 NFVLVFAGALLENAEQLLRMGLSVTEVIEGYELALKKAHEILPKLVIGHVKN-LRNKEEV 670

Query: 160 MNIAGTTLSSKLLTHHKDHFTKLAVEA---VLRLKGSGNLEAIHVIKKLGGSLADSYLDE 216
                T++ SK    ++D    L  +A   VL  K S +++ + V K LG  L  S   +
Sbjct: 671 KTAIRTSVMSKQYG-NEDFLADLITDACVSVLPAKISFSVDNVRVCKILGCGLLQSSTIQ 847

Query: 217 GFLLDKKIGVNQPKRIENAKILIANTGMDTDKIKIFGSRVRVDSTAKVAEIEHAEKEKMK 276
           G +  +++   +  ++E AK+ +    +D+ + +  G+ V + +  ++      E++ M+
Sbjct: 848 GMVFKRQVE-GEITKVEKAKVAVFTCPLDSMQTETKGT-VLIKNAEELMSFSKGEEDMME 1021

Query: 277 EKVERILKHGINCFI 291
           E+++ I + G+N  +
Sbjct: 1022EQIKGIKEAGVNVIV 1066
>29864
          Length = 1026

 Score = 88.6 bits (218), Expect = 6e-18,   Method: Compositional matrix adjust.
 Identities = 71/253 (28%), Positives = 121/253 (47%), Gaps = 6/253 (2%)
 Frame = +1

Query: 5   SLAPVNIFKAGADEERAETARLSSFIGAIAIGDLVKSTLGPKGMDKILLSSGRDAALMVT 64
           +++ +      A+  RA  A   +   A  + D+++S LGPKG  K+L+S   D  L  T
Sbjct: 106 NMSAIKQLNPKAEVARASQALAVNIAAAKGLQDVLRSNLGPKGTMKMLVSGAGDIKL--T 279

Query: 65  NDGATILKNIGVDNPAAKVLVDMSRVQDDEVGDGTTSVTVXXXXXXXXXXSLIAKKIHPQ 124
            DG  +L  + + +P A ++  ++  QDD  GDGTTS  +            IA+ +HP+
Sbjct: 280 KDGNVLLHEMQIQHPTASLIARVATAQDDITGDGTTSNVLIIGELLKQADLYIAEGLHPR 459

Query: 125 TIISGWREATKAAREALLSSAVDHGSDEARFWQDLMNIAGTTLSSKLLTHHKDHFTKLAV 184
            I  G+  A   A E L    V    D     + L+ +A T+L +K+ T   D  T+  V
Sbjct: 460 LITEGFELARNKALEVLEEVKVKREVDR----ETLVQVARTSLRTKVHTELADLLTEHVV 627

Query: 185 EAVLRLKGSG---NLEAIHVIKKLGGSLADSYLDEGFLLDKKIGVNQP---KRIENAKIL 238
           +AVL ++  G   +L  + +++    +  DS L  G ++D   G   P   K  ++A IL
Sbjct: 628 DAVLAIQXPGEGIDLHMVELMEMQHKTDLDSTLVRGLVMDH--GARHPDMKKHTKDAFIL 801

Query: 239 IANTGMDTDKIKI 251
             N  ++ +K ++
Sbjct: 802 TCNVSLEYEKTEV 840
>29631
          Length = 1257

 Score = 83.6 bits (205), Expect = 2e-16,   Method: Compositional matrix adjust.
 Identities = 41/131 (31%), Positives = 70/131 (53%)
 Frame = +3

Query: 11  IFKAGADEERAETARLSSFIGAIAIGDLVKSTLGPKGMDKILLSSGRDAALMVTNDGATI 70
           +       E     +L +      I D++++ LGPK M K+L+       +++TNDG  I
Sbjct: 9   VLNQNTRRESGRKVQLGNIAAGKTIADVIRTCLGPKSMLKMLMDPM--GGIVMTNDGNAI 182

Query: 71  LKNIGVDNPAAKVLVDMSRVQDDEVGDGTTSVTVXXXXXXXXXXSLIAKKIHPQTIISGW 130
           L+ I V +PAAK +++++R QD+E GDGT SV +            + +++HP  II+ +
Sbjct: 183 LREINVQHPAAKSMIEVARTQDEETGDGTKSVIILAGEVLSVAEQFLEQQMHPTVIIAAY 362

Query: 131 REATKAAREAL 141
           R+A +   E L
Sbjct: 363 RQALEDTLEVL 395

 Score = 58.5 bits (140), Expect = 7e-09,   Method: Compositional matrix adjust.
 Identities = 30/69 (43%), Positives = 40/69 (57%)
 Frame = +3

Query: 354  IGEDKLIHFSGVALGEACTIVLRGATQQILDEAERSLHDALCVLAQTVKDPRTVYGGGCS 413
            IG+D           +ACTI+LRGA++ IL E ER+L DA+ V    + DP    GGG S
Sbjct: 1050 IGDDYFTFLVDCKSPKACTILLRGASKDILAEVERNLQDAMNVARNVMIDPHLCPGGGAS 1229

Query: 414  EMLMAHAVT 422
            EM +A A+ 
Sbjct: 1230 EMALAQALN 1256
>33770
          Length = 484

 Score = 78.6 bits (192), Expect = 6e-15,   Method: Compositional matrix adjust.
 Identities = 59/152 (38%), Positives = 89/152 (58%), Gaps = 5/152 (3%)
 Frame = +1

Query: 63  VTNDGATILKNIGVDNPAAKVLVDMSRVQDDEVGDGTTSVTVXXXXXXXXXXSLIAKKIH 122
           +TNDGATILK + V +PAAK+LV++S+ QD E GDGTT+V V           L+AK IH
Sbjct: 34  ITNDGATILKQMQVLHPAAKMLVELSKAQDIEXGDGTTTVVVLAGSLLDASAKLLAKGIH 213

Query: 123 PQTIISGWREATKAAREALLSSAVDHGSDEARFWQDLMNIAGTTLSSKLLTHHKDHFTKL 182
           P  I   +++A     E LL   V       R  + L++ A T+L+SK+++ +      +
Sbjct: 214 PTMISEAFQKAASKCVE-LLDGMVKPLELSDR--ESLLSSASTSLNSKVVSQYSSMLAPI 384

Query: 183 AVEAVLRLKGSG-----NLEAIHVIKKLGGSL 209
           AV+AVL++         +L+ I +IKKLGG++
Sbjct: 385 AVDAVLKVIDPATATNVDLKDIKIIKKLGGTI 480
>17249
          Length = 909

 Score = 57.4 bits (137), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 31/89 (34%), Positives = 49/89 (55%), Gaps = 1/89 (1%)
 Frame = +3

Query: 439 FAKALRMLPTIIADNAGYDSADLVAQLRAAHSEGHI-TAGLDMKEGTIGDMAVLGITESF 497
            ++AL ++   +  N G ++   +  LRA H++G   T G+D   G I DMA  GI E  
Sbjct: 3   ISRALEVISRTLIQNCGANTIRTLTALRAKHAQGQKNTWGIDGNTGNIVDMAEFGIWEPL 182

Query: 498 QVKRQVLLSAAEAAEVILRVDNIIKAAPR 526
            VK QV  +A E A ++LR+D+I+    +
Sbjct: 183 SVKLQVYKTACETAILLLRIDDIVSGTKK 269
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|94374014|ref|XP_993478.1| PREDICTED: similar to
6-phosphogluconate dehydrogenase, decarboxylating isoform 4 [Mus
musculus]
         (483 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

02744                                                                 228   4e-60
26107                                                                  28   8.5  
>02744
          Length = 3030

 Score =  228 bits (581), Expect = 4e-60,   Method: Compositional matrix adjust.
 Identities = 101/146 (69%), Positives = 117/146 (80%)
 Frame = -1

Query: 338  GFMLLRQAATEFGWTLNYGGIALMWRGGCIIRSVFRGKIKDAFERNPELQNLLLDDFFKS 397
            GFML+R+ A E GW LN G IALMWRGGCIIRSVF G IK AF+ NP+L NLLLD FFK 
Sbjct: 3030 GFMLMRETAKELGWKLNMGAIALMWRGGCIIRSVFLGNIKQAFDNNPDLSNLLLDKFFKE 2851

Query: 398  AVDNCQDSWRRVISTGVQAGIPMPCFTTALSFYDGYRHEMLPANLIQAQRDYFGAHTYEL 457
             +  CQ+SWRRV++  V  GIP P F+TAL+F+DGYR   LPANLIQAQRDYFGAHTYE 
Sbjct: 2850 EIIKCQESWRRVMAQAVTLGIPTPAFSTALAFFDGYRSASLPANLIQAQRDYFGAHTYER 2671

Query: 458  LTKPGEFIHTNWTGHGGSVSSSSYNA 483
            L  PG+F+HTNWTGHGG+VSS++Y A
Sbjct: 2670 LDNPGKFVHTNWTGHGGNVSSTTYQA 2593
>26107
          Length = 1338

 Score = 28.1 bits (61), Expect = 8.5,   Method: Compositional matrix adjust.
 Identities = 15/54 (27%), Positives = 23/54 (42%), Gaps = 3/54 (5%)
 Frame = -1

Query: 136 RYGPSLMPGGNKEAWPHIKAIFQAIAAKVGTGEPCCDWVGDEGAG---HFVKMV 186
           R  PSL+      AWP ++ +  ++   +GT   CC        G   H VK +
Sbjct: 984 RSQPSLVTSAVCAAWPPVRPVLPSVLLALGTDTLCCGTAASTRKGNINHAVKSI 823
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|10946972|ref|NP_067513.1| epsilon subunit of coatomer
protein complex [Mus musculus]
         (308 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

25956                                                                 146   5e-60
09902                                                                  33   0.11 
>25956
          Length = 823

 Score =  146 bits (368), Expect(2) = 5e-60,   Method: Compositional matrix adjust.
 Identities = 64/92 (69%), Positives = 82/92 (89%)
 Frame = -2

Query: 217 LLLNGQAACHSAQGRWETAEGVLQEALDKDSGHPETLINLIVLSQHLGKPPEVTNRYLSQ 276
           LLLNGQAAC  AQGR++ AE VLQEALDKDS +PETLIN++VLSQH+GK PEV+NRY+SQ
Sbjct: 555 LLLNGQAACFMAQGRFDDAETVLQEALDKDSNNPETLINMVVLSQHIGKSPEVSNRYVSQ 376

Query: 277 LKDAHRAHPFIKEYQAKENDFDRLAMQYAPSA 308
           LKD+HR+HPF+K+Y  KE++F+R++  YAP+A
Sbjct: 375 LKDSHRSHPFVKDYLQKESEFERISRNYAPTA 280

 Score =  102 bits (255), Expect(2) = 5e-60,   Method: Compositional matrix adjust.
 Identities = 48/88 (54%), Positives = 58/88 (65%)
 Frame = -3

Query: 128 FHDQNPDAALRTLHQGDGLECMAMTIQIXXXXXXXXXXXXXXXXMQDQDEDATLTQLATA 187
           +H+QN DAALR LHQ D LECMA+ I+I                M D DED+ +TQLA A
Sbjct: 821 YHEQNYDAALRALHQSDNLECMALMIEILLKMDRVDLTKKELKRMHDTDEDSIVTQLAQA 642

Query: 188 WVNLAVGGEKLQEAYYIFQELADKCSPT 215
           W NL VGGEK Q+A+YIFQE+ADK + T
Sbjct: 641 WFNLTVGGEKFQDAFYIFQEMADKHAST 558
>09902
          Length = 1917

 Score = 33.5 bits (75), Expect = 0.11,   Method: Compositional matrix adjust.
 Identities = 32/125 (25%), Positives = 54/125 (43%), Gaps = 3/125 (2%)
 Frame = +2

Query: 184  LATAWVNLAVGGEKLQEAYYIFQELADKCSPTLLLLNGQAACHSAQGR--WETAEGVLQE 241
            +  AW    +  +++Q+   +F E  D    +L LLN Q AC + +G      A G + E
Sbjct: 1124 VVAAWYEQGIL-DQVQKQKLLFIETPDAAETSLALLNYQKACENGRGAVLLSVARGKVSE 1300

Query: 242  ALDKDSGHPETLINLIVLSQHLGKPPEVTNRYLSQLKDAHRAHPFIKEYQAKENDFDRL- 300
             +D D  +   +I   V   ++     +    L  L+D          +Q +ENDF    
Sbjct: 1301 GIDFDHHYGRAVIMFGV--PYVYTQSRILKARLEYLRD---------NFQIRENDFLTFD 1447

Query: 301  AMQYA 305
            AM++A
Sbjct: 1448 AMRHA 1462
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|8394490|ref|NP_058605.1| translin-associated factor X
[Mus musculus]
         (290 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

14190                                                                 226   7e-60
06652                                                                  50   8e-07
19370                                                                  28   3.3  
>14190
          Length = 1187

 Score =  226 bits (577), Expect = 7e-60,   Method: Compositional matrix adjust.
 Identities = 131/313 (41%), Positives = 186/313 (59%), Gaps = 56/313 (17%)
 Frame = +3

Query: 22  QRREGKDASLSSPVMLAFKSFQQELDARHDKYERLVKLSRDITVESKRTIFLLHRITSAP 81
            R+   + + +SPV+ AF+ +Q ELD +HD+YER+VKLSRDIT+ESKR IFLL R  +  
Sbjct: 30  NRKRQVNVNENSPVIKAFRCYQTELDTKHDRYERVVKLSRDITIESKRVIFLLQRC-AGE 206

Query: 82  DMEE---ILTESESKLDGVRQ-KILQVAQELSGEDMHQFHRAVTTGLQEYVEAVSFQHFI 137
           D EE   +L E+E KL  +++ K L VA EL G D +Q+ RA + GLQEY+EAVSF  ++
Sbjct: 207 DREEKESVLREAECKLKEIQKTKFLPVALELEGLDHYQYIRAYSPGLQEYIEAVSFYQYL 386

Query: 138 KTRSLISMEEINKQLTF------------------TAEDSGKESK-------TPPAEGQE 172
           KT SL+++ E+ + L F                  T   S  ES+       +P  +G+E
Sbjct: 387 KTGSLVTLPEVEEDLRFAVTAATTQAXGGEGENXATDVSSTSESREGLTDGTSPGKKGEE 566

Query: 173 KQLVTWRLK---------------------------LTPVDYLLGVADLTGELMRMCINS 205
               +  L                            + P++++LG+ADLTGELMR  I S
Sbjct: 567 GSSGSTSLAXEVSSSTSDCLAGTGLXDSRHDRVSVTVPPMEFMLGIADLTGELMRTAIMS 746

Query: 206 VGNGDIDTPFEVSQFLRQVYDGFSFIGNTGPYEVSKKLYTLKQSLAKVENACYALKVRGS 265
           V  G++D P ++ +F+R ++D F+  GNT   E+++K+ TL+QS+ KVENACY LKVRGS
Sbjct: 747 VSAGNLDYPVQICEFMRIIHDAFTAYGNTA-RELTRKMSTLRQSVQKVENACYTLKVRGS 923

Query: 266 EIPKHMLADVFSV 278
           EIPKHMLAD+FS 
Sbjct: 924 EIPKHMLADIFSA 962
>06652
          Length = 902

 Score = 50.4 bits (119), Expect = 8e-07,   Method: Compositional matrix adjust.
 Identities = 30/83 (36%), Positives = 46/83 (55%)
 Frame = +3

Query: 186 DYLLGVADLTGELMRMCINSVGNGDIDTPFEVSQFLRQVYDGFSFIGNTGPYEVSKKLYT 245
           D+L+ +  L  EL R  +N+V +GD   P  VS+FL ++  GF  + N     + K+  +
Sbjct: 306 DFLMALLTLASELSRFAVNAVVSGDPGRPIRVSKFLAELDAGFRLL-NLKNDMLRKRFDS 482

Query: 246 LKQSLAKVENACYALKVRGSEIP 268
           LK S+ KVE   Y L +R S +P
Sbjct: 483 LKYSVQKVEGVVYDLTIR-SLVP 548
>19370
          Length = 815

 Score = 28.5 bits (62), Expect = 3.3,   Method: Compositional matrix adjust.
 Identities = 11/23 (47%), Positives = 18/23 (78%)
 Frame = +2

Query: 66  ESKRTIFLLHRITSAPDMEEILT 88
           E ++T+FLL++ TS PD++ I T
Sbjct: 647 EKRKTLFLLYKTTSIPDLKTIST 715
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31543527|ref|NP_033001.2| protein tyrosine
phosphatase 4a3 [Mus musculus]
         (173 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

14057                                                                 224   1e-59
25697                                                                 215   7e-57
30741                                                                  33   0.042
19962                                                                  31   0.33 
03054                                                                  26   8.5  
>14057
          Length = 1377

 Score =  224 bits (572), Expect = 1e-59,   Method: Compositional matrix adjust.
 Identities = 100/157 (63%), Positives = 130/157 (82%)
 Frame = +2

Query: 3   RMNRPAPVEVSYRHMRFLITHNPSNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEKDG 62
           +  RP P E+ +++MRFLIT  P+++T+  +IE+L+K+GA  VVRVC+ TY +  L+K G
Sbjct: 665 KARRPEPAEIEFKNMRFLITDRPTDSTIDKYIEELQKHGAKHVVRVCDPTYSREVLQKAG 844

Query: 63  ITVVDWPFDDGAPPPGKVVEDWLSLLKAKFYNDPGSCVAVHCVAGLGRAPVLVALALIES 122
           I V+DW FDDG+PPP +VV +W +LLKA+F  +PG CVAVHCVAGLGRAPVLVA+AL+E+
Sbjct: 845 IDVLDWQFDDGSPPPNEVVGNWFNLLKARFKEEPGCCVAVHCVAGLGRAPVLVAIALMEA 1024

Query: 123 GMKYEDAIQFIRQKRRGAINSKQLTYLEKYRPKQRLR 159
           GMKYEDA++ IRQKRRGAINSKQL+YL+ YRPK RLR
Sbjct: 1025GMKYEDAVELIRQKRRGAINSKQLSYLQHYRPKSRLR 1135
>25697
          Length = 470

 Score =  215 bits (548), Expect = 7e-57,   Method: Compositional matrix adjust.
 Identities = 99/156 (63%), Positives = 124/156 (79%)
 Frame = +1

Query: 18  RFLITHNPSNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEKDGITVVDWPFDDGAPPP 77
           RFLIT  P+++TL  FIE+L+K+GA  VVRVC+ TY K  LE +GI V+DW FDDG+PPP
Sbjct: 1   RFLITDRPTDSTLDKFIEELQKHGARHVVRVCDPTYSKEKLETEGIDVMDWQFDDGSPPP 180

Query: 78  GKVVEDWLSLLKAKFYNDPGSCVAVHCVAGLGRAPVLVALALIESGMKYEDAIQFIRQKR 137
             VV +W +LLKA F +DPG CVAVHCVAGLGRAPVLVA+AL+E+GMKYEDA++ IR+KR
Sbjct: 181 KDVVGNWFNLLKASFKDDPGCCVAVHCVAGLGRAPVLVAIALMEAGMKYEDAVELIRRKR 360

Query: 138 RGAINSKQLTYLEKYRPKQRLRFKDPHTHKTRCCVM 173
           RGAINSKQL+YL+ YRP+ RLR K       +C ++
Sbjct: 361 RGAINSKQLSYLQHYRPRSRLRSKANRNGHAQCLIL 468
>30741
          Length = 506

 Score = 33.5 bits (75), Expect = 0.042,   Method: Compositional matrix adjust.
 Identities = 16/50 (32%), Positives = 26/50 (52%)
 Frame = -3

Query: 68  WPFDDGAPPPGKVVEDWLSLLKAKFYNDPGSCVAVHCVAGLGRAPVLVAL 117
           WP D G P    ++ +++S ++A   +       VHC AG+GR    +AL
Sbjct: 393 WP-DHGCPERTSMLLNFVSSVRAHMPHTGAGPTLVHCSAGVGRTGTFIAL 247
>19962
          Length = 410

 Score = 30.8 bits (68), Expect = 0.33,   Method: Compositional matrix adjust.
 Identities = 23/89 (25%), Positives = 38/89 (42%), Gaps = 3/89 (3%)
 Frame = +1

Query: 68  WPFDDGAPPPGKVVEDWLSLLKAKFYNDPGSCVAVHCVAGLGRAPVLVALALIESGMKYE 127
           WP D G P P  +V  W  + +          + VHC AG+GR    +AL ++    +  
Sbjct: 154 WP-DHGVPCPVTLVRFWSYVTRQP--AQLSGPLLVHCSAGIGRTGTYIALDMLTHQAETT 324

Query: 128 DAIQF---IRQKRRGAINSKQLTYLEKYR 153
             +     +R+ R   +N  Q   + +YR
Sbjct: 325 GKVSVFPTVRRIRGQRVNMVQT--ISQYR 405
>03054
          Length = 1125

 Score = 25.8 bits (55), Expect = 8.5,   Method: Compositional matrix adjust.
 Identities = 17/73 (23%), Positives = 32/73 (43%), Gaps = 2/73 (2%)
 Frame = +2

Query: 100 VAVHCVAGLGRAPVLVALALIESGMKYEDAIQFIRQKRRGAINSKQ--LTYLEKYRPKQR 157
           +A  C++GL   P            K+   + F+++K    +  K   L YL+ + P ++
Sbjct: 785 LAWICLSGLLHCPA-----------KWTHKLIFVQKKTEWGLWGKVH*LXYLQNFFPLKQ 931

Query: 158 LRFKDPHTHKTRC 170
           +  K  HT+   C
Sbjct: 932 IPAKWTHTYFNNC 970
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|27229051|ref|NP_080543.2| NECAP endocytosis
associated 1 [Mus musculus]
         (275 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

29138                                                                 225   2e-59
33707                                                                  28   5.4  
>29138
          Length = 709

 Score =  225 bits (573), Expect = 2e-59,   Method: Compositional matrix adjust.
 Identities = 105/174 (60%), Positives = 132/174 (75%)
 Frame = -3

Query: 6   EYESVLCVKPDVSVYRIPPRASNRGYRASDWKLDQPDWTGRLRITSKGKIAYIKLEDKVS 65
           EYESVL VKP+V +Y+IPPRASNRGYRA+DW L +P WTGR+R+ +KG    +KLEDK S
Sbjct: 566 EYESVLIVKPEVFIYKIPPRASNRGYRAADWNLKEPTWTGRMRLVAKGTACILKLEDKTS 387

Query: 66  GELFAQAPVEQYPGIAVETVTDSSRYFVIRIQDGTGRSAFIGIGFTDRGDAFDFNVSLQD 125
             LFA  P+E YPG+A+E V+DSSRYFVIR+QD  GRSAF+G+GF DR D+FD NV+L D
Sbjct: 386 XALFANCPIETYPGVAIEAVSDSSRYFVIRVQDDNGRSAFLGLGFGDRSDSFDLNVALLD 207

Query: 126 HFKWVKQETEISKESQEMDNRPKLDLGFKEGQTIKLSIGNITAKKGGASKPRAS 179
           HFKWVK + +I KE  E   + +LDLGFKEG+TIK+++  IT K G     R +
Sbjct: 206 HFKWVKNQEQIEKEKTE--PKQELDLGFKEGETIKINM-RITKKDGAEGSSRTA 54
>33707
          Length = 551

 Score = 27.7 bits (60), Expect = 5.4,   Method: Compositional matrix adjust.
 Identities = 12/36 (33%), Positives = 19/36 (52%)
 Frame = +2

Query: 1   MAAELEYESVLCVKPDVSVYRIPPRASNRGYRASDW 36
           +AA   + S  C KP +   R+ P +S   +R +DW
Sbjct: 71  LAAPCSWRSTSCTKPVLPT*RMTPCSSASSWRXTDW 178
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|9055242|ref|NP_061278.1| DnaJ (Hsp40) homolog,
subfamily B, member 1 [Mus musculus]
         (340 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

10680                                                                 224   3e-59
20488                                                                 200   6e-52
14550                                                                  82   3e-16
26984                                                                  80   2e-15
12040                                                                  75   4e-14
13998                                                                  70   1e-12
07620                                                                  44   4e-11
02324                                                                  63   2e-10
13422                                                                  53   2e-07
02088                                                                  45   4e-05
18150                                                                  29   0.008
22505                                                                  37   0.012
33922                                                                  35   0.034
33510                                                                  30   0.95 
04176                                                                  29   3.0  
20409                                                                  28   4.3  
17683                                                                  28   6.0  
16427                                                                  27   9.3  
>10680
          Length = 1093

 Score =  224 bits (572), Expect = 3e-59,   Method: Compositional matrix adjust.
 Identities = 114/247 (46%), Positives = 158/247 (63%)
 Frame = -3

Query: 92  YTFHGDPHAMFAEFFGGRNPFDTFFGQRNGEEGMDIDDTFSSFPXXXXXXXXXXXXRSRP 151
           YTFHG+P  +F +FFGG NPF  F+ + +G+  M     F                  R 
Sbjct: 992 YTFHGNPDKVFRDFFGGDNPFQEFYDRVDGDLSMG----FGGL-------------HGRG 864

Query: 152 SQEPTRKKQDPPVTHDLRVSLEEIYSGCTKKMKISHKRLNPDGKSIRNEDKILTIEVKRG 211
           S     KKQDPP+  DL ++LEE++ GCTKKMKIS + +N DG +    DKILTI VK+G
Sbjct: 863 S-----KKQDPPIERDLFLALEEVFHGCTKKMKISRRVMNEDGHTSSIRDKILTITVKKG 699

Query: 212 WKEGTKITFPKEGDQTSNNIPADIVFVLKDKPHNIFKRDGSDVIYPARISLREALCGCTV 271
           WK GTKITFPKEGDQ  NN+PADIVF++KDKPH  F+R+G ++I+ A + L  AL G TV
Sbjct: 698 WKPGTKITFPKEGDQGPNNVPADIVFIVKDKPHPRFRREGLNLIHTANVLLGRALTGTTV 519

Query: 272 NVPTLDGRTIPVVFKDVIRPGMRRKVPGEGLPLPKTPEKRGDLVIEFEVIFPERIPVSSR 331
           ++ TLD RT+ +   D+++PG ++ VPGEG+P+   P ++GDL+IEF + FP  +    +
Sbjct: 518 DIHTLDDRTLHIPINDIVKPGYKKIVPGEGMPMSSDPTQKGDLIIEFNIEFPTSLTPERK 339

Query: 332 TILEQVL 338
            ++   L
Sbjct: 338 DLIRTAL 318
>20488
          Length = 3281

 Score =  200 bits (509), Expect = 6e-52,   Method: Compositional matrix adjust.
 Identities = 94/181 (51%), Positives = 130/181 (71%)
 Frame = -2

Query: 158  KKQDPPVTHDLRVSLEEIYSGCTKKMKISHKRLNPDGKSIRNEDKILTIEVKRGWKEGTK 217
            KKQDPP+  DL ++LEE++ GCTKKMKIS + +N DG +    DKILTI VK+GWK GTK
Sbjct: 1717 KKQDPPIERDLFLALEEVFHGCTKKMKISRRVMNEDGHTSSIRDKILTITVKKGWKPGTK 1538

Query: 218  ITFPKEGDQTSNNIPADIVFVLKDKPHNIFKRDGSDVIYPARISLREALCGCTVNVPTLD 277
            ITFPKEGDQ  NN+PADIVF++KDKPH  F+R+G ++I+ A + L  AL G TV++ TLD
Sbjct: 1537 ITFPKEGDQGPNNVPADIVFIVKDKPHPRFRREGLNLIHTANVLLGRALTGTTVDIHTLD 1358

Query: 278  GRTIPVVFKDVIRPGMRRKVPGEGLPLPKTPEKRGDLVIEFEVIFPERIPVSSRTILEQV 337
             RT+ +   D+++PG ++ VPGEG+P+   P ++GDL+IEF + FP  +    + ++   
Sbjct: 1357 DRTLHIPINDIVKPGYKKIVPGEGMPMSSDPTZKGDLIIEFNIEFPTSLTPERKDLIRTA 1178

Query: 338  L 338
            L
Sbjct: 1177 L 1175
>14550
          Length = 1395

 Score = 82.0 bits (201), Expect = 3e-16,   Method: Compositional matrix adjust.
 Identities = 52/194 (26%), Positives = 90/194 (46%), Gaps = 34/194 (17%)
 Frame = -2

Query: 164 VTHDLRVSLEEIYSG--------------------CTKKMKISHKRLNPDGKSIRN---- 199
           V  DL V+LEE+YSG                    C  +M+   ++L P    +      
Sbjct: 806 VVMDLDVTLEELYSGDFVEVLRYKPVSKPAKGKRKCNCRMETVTQQLGPGRFQMSQQQVC 627

Query: 200 ----------EDKILTIEVKRGWKEGTKITFPKEGDQTSNNIPADIVFVLKDKPHNIFKR 249
                     E+K+L +E++ G ++G +  F  EG+   +  P D+ F+++   H  F+R
Sbjct: 626 DECPNIKFVPEEKVLEVEIEPGMRDGQEYPFVAEGEPHMDGEPGDLRFIIRQVKHARFER 447

Query: 250 DGSDVIYPARISLREALCGCTVNVPTLDGRTIPVVFKDVIRPGMRRKVPGEGLPLPKTPE 309
            G D+     +SL++AL G  +++  LDG  + V+   +  PG R +   EG+P  +   
Sbjct: 446 KGDDLYTNVTVSLQDALIGFEMDIVHLDGHKVHVIRDKITWPGARMRKSNEGMPNYENNN 267

Query: 310 KRGDLVIEFEVIFP 323
            +G L I F++ FP
Sbjct: 266 VKGSLFITFDIDFP 225

 Score = 70.9 bits (172), Expect = 7e-13,   Method: Compositional matrix adjust.
 Identities = 32/67 (47%), Positives = 52/67 (77%), Gaps = 1/67 (1%)
 Frame = -1

Query: 2    GKDYYQTLGLARGASDDEIKRAYRRQALRYHPDKNK-EPGAEEKFKEIAEAYDVLSDPRK 60
            G+D+Y+ LG+++ A   +IKRAYR+ A   HPDKN+ +P AE++F+++  AY+VLSD  K
Sbjct: 1140 GRDFYKILGVSKSADTKQIKRAYRKIAKELHPDKNRDDPEAEQRFQDLGAAYEVLSDEEK 961

Query: 61   REIFDRY 67
            R+++DR+
Sbjct: 960  RKVYDRH 940
>26984
          Length = 1107

 Score = 79.7 bits (195), Expect = 2e-15,   Method: Compositional matrix adjust.
 Identities = 37/66 (56%), Positives = 49/66 (74%)
 Frame = -2

Query: 2   GKDYYQTLGLARGASDDEIKRAYRRQALRYHPDKNKEPGAEEKFKEIAEAYDVLSDPRKR 61
           GKD Y  LGL   ASD++IKR YRRQA+  HPDKN+EPGAEE FK +  A++++ DP KR
Sbjct: 521 GKDPYSILGLRADASDEDIKRYYRRQAVLVHPDKNQEPGAEEAFKILGHAFEMIGDPTKR 342

Query: 62  EIFDRY 67
           + +D +
Sbjct: 341 KEYDTH 324
>12040
          Length = 1151

 Score = 74.7 bits (182), Expect = 4e-14,   Method: Compositional matrix adjust.
 Identities = 43/108 (39%), Positives = 65/108 (60%), Gaps = 2/108 (1%)
 Frame = -2

Query: 234  DIVFVLKDKPHNIFKRDGSDVIYPARISLREALCGCTVNVPTLDGRTIPVVFK--DVIRP 291
            DI+ +L +K H+ F   G+D++    + L EALCG    V T+D R + V  +  +VIR 
Sbjct: 1150 DIIILLDEKEHSTFVHAGTDLMMKMPLQLVEALCGFQRIVKTMDDRDLLVATQPGEVIRH 971

Query: 292  GMRRKVPGEGLPLPKTPEKRGDLVIEFEVIFPERIPVSSRTILEQVLP 339
             M + +  EG+P+ K P ++G L+I+FEVIFP+ I  S    L+Q LP
Sbjct: 970  EMTKCIAEEGMPIFKNPMEKGTLIIQFEVIFPDVINPSVIPTLKQCLP 827
>13998
          Length = 1075

 Score = 69.7 bits (169), Expect = 1e-12,   Method: Compositional matrix adjust.
 Identities = 45/122 (36%), Positives = 61/122 (50%), Gaps = 9/122 (7%)
 Frame = +1

Query: 3   KDYYQTLGLARGASDDEIKRAYRRQALRYHPDKNKEPGA------EEKFKEIAEAYDVLS 56
           KDYY+ LG++R A++DEIK+AYR++AL +HPD++    A      E KFKE+ EAY +LS
Sbjct: 202 KDYYKILGISRNATEDEIKKAYRKKALVHHPDRHANSSADVRKDEELKFKEVGEAYAILS 381

Query: 57  DPRKREIFDRYXXXXXXXXXXXXXXXXXXXXXXXXYTFHGDPHAMFAEFF---GGRNPFD 113
           D  K+  +D                               DP+ MF  FF   GGRN   
Sbjct: 382 DGAKKTRYD------------------SGHDIQDEMQADFDPNQMFRSFFQFSGGRNSSF 507

Query: 114 TF 115
            F
Sbjct: 508 NF 513
>07620
          Length = 1775

 Score = 44.3 bits (103), Expect(2) = 4e-11,   Method: Compositional matrix adjust.
 Identities = 30/81 (37%), Positives = 35/81 (43%), Gaps = 2/81 (2%)
 Frame = +3

Query: 33  PDKNKEPGAEEKFKEIAEAYDVLSDPRKREIFDRYXXXXXXXXXXXXXXXXXXXXXXXXY 92
           P +NK PGA + FK+I  AY VLSDP KR  +D Y                         
Sbjct: 186 PRQNKAPGATDAFKKIGNAYSVLSDPDKRRKYDVYGPELQQPSQHHSEYSNG-------- 341

Query: 93  TFHGD--PHAMFAEFFGGRNP 111
            F GD  P  +F  FFGG  P
Sbjct: 342 GFEGDITPEELFNMFFGGGYP 404

 Score = 40.8 bits (94), Expect(2) = 4e-11,   Method: Compositional matrix adjust.
 Identities = 15/36 (41%), Positives = 26/36 (72%)
 Frame = +1

Query: 2   GKDYYQTLGLARGASDDEIKRAYRRQALRYHPDKNK 37
            KDYY+ L + +  ++ ++K+AYR+ AL+ HPDK +
Sbjct: 94  CKDYYEVLDVKKDCTESDMKKAYRKLALQMHPDKTR 201
>02324
          Length = 2058

 Score = 62.8 bits (151), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 27/65 (41%), Positives = 49/65 (75%), Gaps = 2/65 (3%)
 Frame = +2

Query: 5   YYQTLGLARGASDDEIKRAYRRQALRYHPDKNKEP--GAEEKFKEIAEAYDVLSDPRKRE 62
           +Y+ LG+ R A +D++K+AYR+ AL++HPDKN +    A  +F+ + +AY++L+DP++R 
Sbjct: 107 HYEVLGVERSADNDDLKKAYRKLALKFHPDKNPDSVEEATAQFRLVQQAYEILTDPQERS 286

Query: 63  IFDRY 67
            +DR+
Sbjct: 287 WYDRH 301
>13422
          Length = 930

 Score = 53.1 bits (126), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 30/72 (41%), Positives = 43/72 (59%), Gaps = 9/72 (12%)
 Frame = +1

Query: 3   KDYYQTLGLAR---GASDDEIKRAYRRQALRYHPDKNK------EPGAEEKFKEIAEAYD 53
           +D+Y  LGL++    A+ D IKR YR++ L +HPDK +      E G  + F  I+ AY+
Sbjct: 334 QDHYAVLGLSKLRYKATADHIKRIYRQKVLLHHPDKRRARGLHVENGENDYFLCISRAYE 513

Query: 54  VLSDPRKREIFD 65
           +L DP KR  FD
Sbjct: 514 ILGDPVKRRSFD 549
>02088
          Length = 1062

 Score = 45.1 bits (105), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 23/65 (35%), Positives = 38/65 (58%), Gaps = 3/65 (4%)
 Frame = +3

Query: 4   DYYQTLGLARGASDDEIKRAYRRQALRYHPDK---NKEPGAEEKFKEIAEAYDVLSDPRK 60
           D Y+ +G+ R A+  E+K+ Y + +L  HPD+    ++  A  KF+ + + Y VLSD  K
Sbjct: 108 DLYEVIGIRREATPQEVKKGYHKVSLAVHPDQVSAAEKETATRKFQTLGKVYTVLSDKDK 287

Query: 61  REIFD 65
           R  +D
Sbjct: 288 RAXYD 302
>18150
          Length = 768

 Score = 29.3 bits (64), Expect(2) = 0.008,   Method: Compositional matrix adjust.
 Identities = 14/38 (36%), Positives = 24/38 (63%), Gaps = 4/38 (10%)
 Frame = +3

Query: 15 ASDDEIKRAYRRQALRYHPDKN----KEPGAEEKFKEI 48
          A+ +E+  A+RR +  YHPDK+    K+  AE+ F ++
Sbjct: 3  ATTEEVNNAFRRLSKIYHPDKHLEAAKKKAAEDMFNQL 116

 Score = 27.3 bits (59), Expect(2) = 0.008,   Method: Compositional matrix adjust.
 Identities = 10/18 (55%), Positives = 14/18 (77%)
 Frame = +2

Query: 50  EAYDVLSDPRKREIFDRY 67
           EA+++LSD  KR I+D Y
Sbjct: 119 EAHEILSDKHKRTIYDTY 172
>22505
          Length = 784

 Score = 37.0 bits (84), Expect = 0.012,   Method: Compositional matrix adjust.
 Identities = 16/37 (43%), Positives = 25/37 (67%)
 Frame = -1

Query: 1   MGKDYYQTLGLARGASDDEIKRAYRRQALRYHPDKNK 37
           M  D Y  LG+   A++ +I +AYR++AL+ HPDK +
Sbjct: 661 MKMDLYGILGVGPEANEKQIVKAYRKKALKCHPDKTQ 551
>33922
          Length = 832

 Score = 35.4 bits (80), Expect = 0.034,   Method: Compositional matrix adjust.
 Identities = 21/77 (27%), Positives = 36/77 (46%)
 Frame = -1

Query: 202 KILTIEVKRGWKEGTKITFPKEGDQTSNNIPADIVFVLKDKPHNIFKRDGSDVIYPARIS 261
           K + + V  G ++G  +  P  G         ++    +     IF+R+G+DV     +S
Sbjct: 814 KKVVVPVPAGVEDGQTVRMPMSGQ--------ELFITFRVAKSKIFRREGADVHSDVTVS 659

Query: 262 LREALCGCTVNVPTLDG 278
           L +A+ G TV VP + G
Sbjct: 658 LTQAILGGTVRVPGIYG 608
>33510
          Length = 501

 Score = 30.4 bits (67), Expect = 0.95,   Method: Compositional matrix adjust.
 Identities = 17/63 (26%), Positives = 31/63 (49%), Gaps = 4/63 (6%)
 Frame = +3

Query: 6   YQTLGLARGASDDEIKRAYRRQALRYHPDKN----KEPGAEEKFKEIAEAYDVLSDPRKR 61
           ++  G+    S D++K+ YR+  L  HPDK      E  A+  F E+ +A+    D   +
Sbjct: 264 WKPCGMHDLVSADQVKKVYRKAVLSVHPDKLHDDPHEALAKLIFMELNDAWAKFEDEGMK 443

Query: 62  EIF 64
            ++
Sbjct: 444 SLY 452
>04176
          Length = 2034

 Score = 28.9 bits (63), Expect = 3.0,   Method: Compositional matrix adjust.
 Identities = 12/33 (36%), Positives = 18/33 (54%)
 Frame = -2

Query: 251 GSDVIYPARISLREALCGCTVNVPTLDGRTIPV 283
           G D++   R  + E + GC V  PTL G+ + V
Sbjct: 410 GHDLVQVVRGHIHEGVVGCVVQRPTLTGQVVEV 312
>20409
          Length = 396

 Score = 28.5 bits (62), Expect = 4.3,   Method: Compositional matrix adjust.
 Identities = 13/24 (54%), Positives = 15/24 (62%)
 Frame = +2

Query: 98  PHAMFAEFFGGRNPFDTFFGQRNG 121
           P  +F EFFGG +PF  FF   NG
Sbjct: 284 PEEVFREFFGGNSPFADFFRDANG 355
>17683
          Length = 450

 Score = 28.1 bits (61), Expect = 6.0,   Method: Compositional matrix adjust.
 Identities = 11/31 (35%), Positives = 18/31 (58%)
 Frame = +2

Query: 7   QTLGLARGASDDEIKRAYRRQALRYHPDKNK 37
           Q  G++      E+K+ Y++  + YHPDK K
Sbjct: 356 QDGGVSANPEWSEVKKLYQKAVIHYHPDKVK 448
>16427
          Length = 1313

 Score = 27.3 bits (59), Expect = 9.3,   Method: Compositional matrix adjust.
 Identities = 13/47 (27%), Positives = 22/47 (46%)
 Frame = +1

Query: 291 PGMRRKVPGEGLPLPKTPEKRGDLVIEFEVIFPERIPVSSRTILEQV 337
           PG+  +VPG   P+  TP +   +    E   P     +SR ++ +V
Sbjct: 886 PGITHQVPGTTRPVVTTPARETTVRSAVETDIPTETATASRAVMTEV 1026
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31560309|ref|NP_067504.2| phosphatase subunit gene
g4-1 [Mus musculus]
         (453 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

00992                                                                 224   5e-59
08051                                                                  74   1e-20
26019                                                                  30   1.6  
>00992
          Length = 1754

 Score =  224 bits (572), Expect = 5e-59,   Method: Compositional matrix adjust.
 Identities = 101/144 (70%), Positives = 127/144 (88%)
 Frame = +2

Query: 305 TMTNVFLDRVFQECLTYDGEMDYKTYLDFVLALENRKEPAALQYIFKLLDIENKGYLNVF 364
           T+T+VFLDRVFQECLTY+GEMDYKTYLDFVLA+ENR+EP AL+Y+F++LD++++GYLNVF
Sbjct: 2   TLTDVFLDRVFQECLTYEGEMDYKTYLDFVLAMENRREPQALRYLFRILDVQHRGYLNVF 181

Query: 365 SLNYFFRAIQELMKIHGQDPVSFQDVKDEIFDMVKPKDPLKISLQDLINSNQGDTVTTIL 424
           +LN+FFRAIQ  MK+ GQ+PVS +D+KDEIFDMVKP DPLK++L DLI+  +GDTV  IL
Sbjct: 182 ALNFFFRAIQGQMKLRGQEPVSLEDIKDEIFDMVKPADPLKLTLNDLISCGKGDTVACIL 361

Query: 425 IDLNGFWTYENREALVANDNENSA 448
           IDLN FWTYENRE LV + N+  +
Sbjct: 362 IDLNDFWTYENREYLVTDQNDQES 433
>08051
          Length = 1007

 Score = 73.6 bits (179), Expect(2) = 1e-20,   Method: Compositional matrix adjust.
 Identities = 35/128 (27%), Positives = 69/128 (53%)
 Frame = +1

Query: 324 EMDYKTYLDFVLALENRKEPAALQYIFKLLDIENKGYLNVFSLNYFFRAIQELMKIHGQD 383
           +M Y  ++ F+L+ E+++ P A++Y F+ +DI+  G L+++ L YF+   Q+ M+  G +
Sbjct: 424 KMSYTDFVWFILSEEDKRTPTAIEYWFRCMDIDGDGALSMYELEYFYEEQQQRMEGIGIE 603

Query: 384 PVSFQDVKDEIFDMVKPKDPLKISLQDLINSNQGDTVTTILIDLNGFWTYENREALVAND 443
            + F+D   ++ DM+KP +   I+L DL              +L  +  +E R+   +  
Sbjct: 604 CLPFEDCLCQMLDMIKPANRDSITLGDLKRCKMTHVFFDTFFNLEKYLDHEQRDPFASQR 783

Query: 444 NENSADLD 451
           +E + D D
Sbjct: 784 DETNTDWD 807

 Score = 44.7 bits (104), Expect(2) = 1e-20,   Method: Compositional matrix adjust.
 Identities = 30/130 (23%), Positives = 67/130 (51%), Gaps = 6/130 (4%)
 Frame = +2

Query: 192 DLENYILELIPTLPQLDGLEKS--FYSFYVCTAVRKFFFFLDPLRTGKIKIQDILACSFX 249
           DL   + +++ T P L  L+++  F+S YV T + + F+ ++   +GKI I ++      
Sbjct: 2   DLVPMVQDVVDTHPGLAFLKEATEFHSRYVHTVIARIFYSVNRSWSGKITISELKRSDLL 181

Query: 250 XXXXXXXXXXXSKESQETN----WFSAPSALRVYGQYLNLDKDHNGMLSKEELSRYGTAT 305
                       +E ++ N    +FS      +Y ++  LDKDH+ ++S+++L+++    
Sbjct: 182 EMISLL------EEEEDINQIMAFFSYEHFYVIYCKFWELDKDHDLLISQDDLAKHSDNA 343

Query: 306 MTNVFLDRVF 315
           ++   ++R+F
Sbjct: 344 LSTRIVERIF 373
>26019
          Length = 1561

 Score = 30.4 bits (67), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 24/89 (26%), Positives = 49/89 (55%), Gaps = 3/89 (3%)
 Frame = +2

Query: 277 RVYGQYLNLDKDHNGMLSKEELSRYGTATMTNVFLDRVFQECLT-YDGEMDYKTYLDFV- 334
           R+  ++  LD D++G LS +E          N  + RV     T  +GE+D+K +++ + 
Sbjct: 101 RLGKRFRKLDLDNSGSLSIDEFMSL-PELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGIS 277

Query: 335 -LALENRKEPAALQYIFKLLDIENKGYLN 362
             +++  KE + L++ FK+ D++  GY++
Sbjct: 278 QFSVKGDKE-SKLRFAFKIYDMDKDGYIS 361
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|94385700|ref|XP_001002286.1| PREDICTED: similar to
zinc finger protein 291 isoform 9 [Mus musculus]
         (1398 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

02949                                                                 222   5e-59
04237                                                                 158   1e-38
38473                                                                 152   1e-36
18890                                                                  97   4e-20
30018                                                                  32   1.4  
07311                                                                  31   3.5  
19993                                                                  30   4.7  
03957                                                                  30   6.1  
12470                                                                  30   7.0  
>02949
          Length = 1076

 Score =  222 bits (565), Expect(2) = 5e-59,   Method: Compositional matrix adjust.
 Identities = 111/216 (51%), Positives = 142/216 (65%), Gaps = 1/216 (0%)
 Frame = +3

Query: 1134 FLQHAAGFLRGMCMLCFAVTGRSSSIFDNNH-QDPTGLTAALQATDLAGVLHMLYCILFH 1192
            FLQ++ G L  M      ++ R+S+IFD     DPT L A  + TDL G++ +LY +L H
Sbjct: 21   FLQNSLGLLVAMTKF---MSKRNSNIFDKKKLDDPTQLIATFEVTDLVGIVSLLYGMLLH 191

Query: 1193 GTISDAGTSPKDSYTQNTIQVAIQSLRFFNSFAILDLSAFQSVVGAEGLSLAFRHMASSL 1252
                  G +     +  T+ +    LR  N  A+LDL   Q  +G EG+SL FRH+AS L
Sbjct: 192  SGAPSRGDAAPPELSAQTLAITSSGLRMLNHMAVLDLPMLQRSLGEEGMSLEFRHIASYL 371

Query: 1253 LGHCSQVSCESLLHEVIVCVGYFTVNHPDNQVIVQSGRHPTVLQKLCQLPFQYFSDPRLI 1312
              +     CE LLHEVI+CVGYFTV +PDNQVI+QSG+ PTVLQ+LC LPFQYFSDPRL 
Sbjct: 372  TWYSGVHLCEDLLHEVILCVGYFTVLNPDNQVILQSGQPPTVLQQLCSLPFQYFSDPRLT 551

Query: 1313 KVLFPSLITACHNNHQNKLILEQEMSCVLLATFIQD 1348
             +LFPSLI  C+NNH N+ ILEQE+SCVLLA FI++
Sbjct: 552  TILFPSLIACCYNNHSNRNILEQELSCVLLANFIEE 659

 Score = 25.8 bits (55), Expect(2) = 5e-59,   Method: Composition-based stats.
 Identities = 9/19 (47%), Positives = 12/19 (63%)
 Frame = +2

Query: 1374 LELANRFPQQAWEEARQFF 1392
            + L  RFPQ+ W  A Q+F
Sbjct: 740  MSLMYRFPQEQWMAAEQYF 796
>04237
          Length = 2632

 Score =  158 bits (399), Expect = 1e-38,   Method: Compositional matrix adjust.
 Identities = 81/140 (57%), Positives = 96/140 (68%), Gaps = 8/140 (5%)
 Frame = +1

Query: 1261 CESLLHEVIVCVGYFTVNHPDNQVIVQSGRHPTVLQKLCQLPFQYFSDPRLIKVLFPSLI 1320
            CE LLHEVI+CVGYFTV +PDNQVI+QSG+ PTVLQ+LC LPFQYFSDPRL  +LFPSLI
Sbjct: 7    CEDLLHEVILCVGYFTVLNPDNQVILQSGQPPTVLQQLCSLPFQYFSDPRLTTILFPSLI 186

Query: 1321 TACHNNHQNKLILEQEMSCVLLATFI-------QDFAQTPGHVDNQSSSLKGKFQNPGNY 1373
              C+NNH N+ ILEQE+SCVLLA FI       Q     P  V  + S  + K    G+ 
Sbjct: 187  ACCYNNHSNRNILEQELSCVLLANFIEEKELEQQQIKLIPSTV--KKSKTQDKDTREGDT 360

Query: 1374 -LELANRFPQQAWEEARQFF 1392
             + L  RFPQ+ W  A Q+F
Sbjct: 361  RMSLMYRFPQEQWMAAEQYF 420
>38473
          Length = 654

 Score =  152 bits (384), Expect = 1e-36,   Method: Compositional matrix adjust.
 Identities = 87/224 (38%), Positives = 135/224 (60%), Gaps = 6/224 (2%)
 Frame = -1

Query: 918  QDSGSWVNNKASALDRTLGEIARILEKENVPDQISFQVAGGLTALENILQVV---TPATN 974
            QD+G W +NK SALDR LGE+ARI++++N+ DQ +F+V GGL ++  +L ++   +PA  
Sbjct: 651  QDTGPWPHNKVSALDRNLGEMARIMDRKNMADQNNFRVLGGLASVSRVLNLIEGSSPA-- 478

Query: 975  MNTVSRIPPKSLCNAINVYSLACNNCSENCTDVLFSNKITFLMDLLIHQLTVYVPDENNA 1034
            M TV  IPPKSL  A +VY +AC    ++C   LFSNKI  L+D LIH+L++ +P +   
Sbjct: 477  MPTV--IPPKSLSLACDVYRVACKGNFDSCRYTLFSNKIGVLVDHLIHRLSLMIPSDQPM 304

Query: 1035 VLGRNTNKQ---VFEGLTTGLLRAGAVVFSCLIANRPDGNSRPATPKISTQEMKNKPSQG 1091
             L    +++    F+G+ + L+     V SCL  + P  NS  A+       ++   + G
Sbjct: 303  KLSGGGDQKGCLPFDGVASSLMSVLTTVLSCLAKHSPACNSSEAS-------LERMSATG 145

Query: 1092 DAFNSRVQDLISYVVNMGLIDRLHGCFLSVQGPVDENPKMATFL 1135
            D    R  D+ISY++++G+ID+L   F +V+GPVD +     FL
Sbjct: 144  DTMTCRSNDIISYIISVGVIDKLKWYFSAVRGPVDGDKNAQEFL 13
>18890
          Length = 441

 Score = 97.4 bits (241), Expect = 4e-20,   Method: Compositional matrix adjust.
 Identities = 45/81 (55%), Positives = 57/81 (70%), Gaps = 1/81 (1%)
 Frame = -3

Query: 106 FDNLRRAVDEIYVTCESDQSVVECKEVLMMLDYYVRDFKALIDWIQLQEKLEKTDAQS-R 164
           FDN +RAVD IY TCE D+SVVECKEV+MML+   +DFK+LI+ + +    E       R
Sbjct: 337 FDNFQRAVDAIYQTCEQDESVVECKEVIMMLEQSTKDFKSLIERLHIMRAFEDAAKDGDR 158

Query: 165 PTSLAWEVKKMSPGRHVIQSP 185
           P S+AWEV+KMSPG+H   SP
Sbjct: 157 PPSIAWEVRKMSPGKHTSASP 95
>30018
          Length = 1267

 Score = 32.3 bits (72), Expect = 1.4,   Method: Composition-based stats.
 Identities = 12/32 (37%), Positives = 21/32 (65%)
 Frame = -1

Query: 792  QCSLCNVLIASEVYLFSHIKGKKHQQAVRENS 823
            +C +C V++ SE  L  H+KG KH   ++++S
Sbjct: 1123 ECEMCGVIVTSEEQLAMHLKGVKHLNKMKQHS 1028
>07311
          Length = 2662

 Score = 30.8 bits (68), Expect = 3.5,   Method: Compositional matrix adjust.
 Identities = 12/27 (44%), Positives = 16/27 (59%)
 Frame = -1

Query: 793 CSLCNVLIASEVYLFSHIKGKKHQQAV 819
           C+ CN++       F HI+ KKHQQ V
Sbjct: 469 CATCNMVCGHMFDYFKHIETKKHQQRV 389
>19993
          Length = 1602

 Score = 30.4 bits (67), Expect = 4.7,   Method: Compositional matrix adjust.
 Identities = 11/30 (36%), Positives = 18/30 (60%)
 Frame = +3

Query: 789 RKKQCSLCNVLIASEVYLFSHIKGKKHQQA 818
           RK QC  C V  + + YL  H++ ++HQ+ 
Sbjct: 330 RKFQCQQCKVAFSRQTYLILHLRTQQHQRG 419
>03957
          Length = 908

 Score = 30.0 bits (66), Expect = 6.1,   Method: Compositional matrix adjust.
 Identities = 12/27 (44%), Positives = 16/27 (59%)
 Frame = +1

Query: 793 CSLCNVLIASEVYLFSHIKGKKHQQAV 819
           C+ CN++       F HI+ KKHQQ V
Sbjct: 265 CATCNMVCGHMFDYFKHIETKKHQQKV 345
>12470
          Length = 562

 Score = 30.0 bits (66), Expect = 7.0,   Method: Compositional matrix adjust.
 Identities = 17/44 (38%), Positives = 26/44 (59%), Gaps = 2/44 (4%)
 Frame = +2

Query: 960  TALENILQVVTPATNMNTVSRIPPKSLCNAINVYS--LACNNCS 1001
            ++   + Q V PAT    +S +PP S C+A++  S  LAC+ CS
Sbjct: 296  SSCPCLCQTVLPATCDEALSSLPPLSPCSAVS*SSCWLACSQCS 427
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|145966911|ref|NP_080487.2| transmembrane emp24
protein transport domain containing 9 [Mus musculus]
         (235 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

03595                                                                 216   6e-59
19964                                                                  76   1e-14
38580                                                                  28   4.2  
>03595
          Length = 1492

 Score =  216 bits (550), Expect(2) = 6e-59,   Method: Compositional matrix adjust.
 Identities = 105/141 (74%), Positives = 123/141 (87%)
 Frame = +3

Query: 95  KVILARQYGSEGRFTFTSHTPGEHQICLHSNSTKFSLFAGGMLRVHLDIQVGEHANDYAE 154
           K++++R Y +EGRFTFTSH+ GEH ICL+SNST + L+AG  LRVHLDI VGEHA DY +
Sbjct: 42  KIVMSRTYAAEGRFTFTSHSAGEHIICLNSNSTAW-LYAG-QLRVHLDISVGEHAVDYQQ 215

Query: 155 IAAKDKLSELQLRVRQLVEQVEQIQKEQNYQRWREERFRQTSESTNQRVLWWSILQTLIL 214
           + AKDKLSELQLR+RQL++QVEQI KEQNYQR+REERFRQTSESTN RVLWWSI QTLIL
Sbjct: 216 VQAKDKLSELQLRIRQLLDQVEQITKEQNYQRYREERFRQTSESTNHRVLWWSIAQTLIL 395

Query: 215 VAIGVWQMRHLKSFFEAKKLV 235
           +  G WQM+HLKSFF+AKKLV
Sbjct: 396 LLTGFWQMQHLKSFFQAKKLV 458

 Score = 28.9 bits (63), Expect(2) = 6e-59,   Method: Compositional matrix adjust.
 Identities = 10/16 (62%), Positives = 14/16 (87%)
 Frame = +1

Query: 81 PGLGMFVEVKDPEDKV 96
          PG+GM VEV+DP +K+
Sbjct: 1  PGIGMHVEVRDPSEKL 48
>19964
          Length = 901

 Score = 76.3 bits (186), Expect = 1e-14,   Method: Compositional matrix adjust.
 Identities = 46/155 (29%), Positives = 82/155 (52%), Gaps = 2/155 (1%)
 Frame = +2

Query: 83  LGMFVEVKDPEDKVILARQYGSEGRFTFTSHTPGEHQICLHSNSTKFSLFAGGMLRVHLD 142
           L + V++  P++KVI   +  S G++TF +H  G ++ C    S + S     ++   +D
Sbjct: 65  LDIDVKIYGPDNKVIHQGERESNGKYTFAAHMDGIYKYCF---SNQMSTMTPKVVMFSMD 235

Query: 143 I--QVGEHANDYAEIAAKDKLSELQLRVRQLVEQVEQIQKEQNYQRWREERFRQTSESTN 200
           +  +  +   D    A+  KL E+   V QL   +   + EQ Y   RE   R  +++TN
Sbjct: 236 VGEKPKDQDGDKDSDASHGKLEEM---VNQLSTALTGAKHEQEYMEVRERIHRAINDNTN 406

Query: 201 QRVLWWSILQTLILVAIGVWQMRHLKSFFEAKKLV 235
            RV+ W+  + L+LVA+ + Q+ +LK FFE +++V
Sbjct: 407 SRVVLWAFFEALVLVAMSLGQVYYLKRFFEVRRVV 511
>38580
          Length = 727

 Score = 27.7 bits (60), Expect = 4.2,   Method: Compositional matrix adjust.
 Identities = 11/27 (40%), Positives = 20/27 (74%)
 Frame = +3

Query: 206 WSILQTLILVAIGVWQMRHLKSFFEAK 232
           WS+ +++++V IG+ Q+  L+SFF  K
Sbjct: 609 WSVGESILIVLIGIGQILVLRSFFTNK 689
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|27370038|ref|NP_766299.1| GUF1 GTPase homolog [Mus
musculus]
         (651 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

13184                                                                 224   7e-59
20584                                                                 201   8e-52
15617                                                                  97   2e-20
00709                                                                  65   1e-10
15991                                                                  52   5e-07
22349                                                                  52   8e-07
18903                                                                  45   9e-05
01452                                                                  30   4.0  
>13184
          Length = 847

 Score =  224 bits (572), Expect = 7e-59,   Method: Compositional matrix adjust.
 Identities = 98/186 (52%), Positives = 141/186 (75%)
 Frame = +1

Query: 453 EPVVLGTVITPTEYTGKIMALCQARRAIQKNMTFIDENRVMLKYLFPLNEIVVDFYDSLK 512
           EP+V GTVI P +Y G + +LC  RR + ++   ID + +ML   FPLNEI+VDF+D LK
Sbjct: 1   EPMVKGTVICPDQYLGGVTSLCLDRRGVIEDQLNIDNSHIMLIIKFPLNEILVDFFDDLK 180

Query: 513 SLSSGYASFDYEDAGYQTAELVKMDILLNGNMVEELVTVVHREKAYTVGKSICERLKESL 572
           S++SGYASFDYEDAGY+T+ L ++D LLNG+ V+EL  + H  +A  + K +CE+L++++
Sbjct: 181 SITSGYASFDYEDAGYETSSLARVDFLLNGSAVDELSMISHTTRARAMAKRVCEKLRDTI 360

Query: 573 PRQLYEIAIQAAVGSKVIARETVKAYRKNVLAKCYGGDITRKMKLLKRQSEGKKKLRKIG 632
           PRQ + I++Q AVG KV+ARE ++ +RK+V AKCYGGDI+RKMKLLKRQ+EGK+   ++ 
Sbjct: 361 PRQQFAISVQGAVGGKVLAREDIRPFRKDVTAKCYGGDISRKMKLLKRQTEGKRNCERLA 540

Query: 633 NIEIPK 638
            ++ PK
Sbjct: 541 TLKSPK 558

 Score = 43.1 bits (100), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 20/22 (90%), Positives = 22/22 (100%)
 Frame = +3

Query: 625 KKKLRKIGNIEIPKDAFIKVLK 646
           KKKLRKIGNIE+PKDAFIKVL+
Sbjct: 516 KKKLRKIGNIEVPKDAFIKVLR 581
>20584
          Length = 561

 Score =  201 bits (511), Expect = 8e-52,   Method: Compositional matrix adjust.
 Identities = 92/152 (60%), Positives = 116/152 (76%)
 Frame = +1

Query: 261 VVSKGDKIVSAHTKKAYEVNEVGILNPNEQPTHKLYAGQVGFLIAGMKDVTEAQIGDTLY 320
           V   GDK+V   + K YEV E+G ++P  QP   LYAGQVG++I  M++  EAQIGDT  
Sbjct: 1   VARTGDKVVCMSSSKVYEVQEIGFMHPTPQPAEALYAGQVGYIITNMRNTQEAQIGDTFC 180

Query: 321 LHNHPVEPLPGFKSAKPMVFAGVYPIDQSEYNNLKSAIEKLTLNDSSVTVHRDSSLALGA 380
                V+PLPGFK AK MVFAG++P DQSE+  L++A+E+LTLNDSSV+VH DSS ALG 
Sbjct: 181 HEKSDVQPLPGFKPAKAMVFAGLFPSDQSEFLGLRNAMERLTLNDSSVSVHTDSSPALGQ 360

Query: 381 GWRLGFLGLLHMEVFNQRLEQEYNASVILTTP 412
           G+R+GFLGLLHM+VF QRLEQE+NAS I+T+P
Sbjct: 361 GFRMGFLGLLHMDVFCQRLEQEFNASFIVTSP 456
>15617
          Length = 595

 Score = 96.7 bits (239), Expect = 2e-20,   Method: Compositional matrix adjust.
 Identities = 56/146 (38%), Positives = 80/146 (54%), Gaps = 15/146 (10%)
 Frame = -3

Query: 48  EDIRNFSIIAHVDHGKSTLADRLLELTGTIDKTKKNK-QVLDKLQVERERGITVKAQTAS 106
           ++IRN S+IAHVDHGKSTL D L+   G I   K  + +  D  + E+ER IT+K+   S
Sbjct: 440 KNIRNMSVIAHVDHGKSTLTDSLVSKAGIIASAKAGETRFTDTRKDEQERCITIKSTAIS 261

Query: 107 LFYSF--------------GGKQYLLNLIDTPGHVDFSYEVSRSLSACQGVLLVVDANEG 152
           L+Y                    +L+NLID+PGHVDFS EV+ +L    G L+VVD   G
Sbjct: 260 LYYELKKDDMKYIKQDYDQDNNAFLINLIDSPGHVDFSSEVTAALRVTDGALVVVDCVSG 81

Query: 153 IQAQTVANFFLAFEAQLSVIPVINKI 178
           +  QT      A   ++  + ++NK+
Sbjct: 80  VCVQTETVLRQAIGERIRPVLMMNKM 3
>00709
          Length = 1076

 Score = 64.7 bits (156), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 48/152 (31%), Positives = 68/152 (44%), Gaps = 24/152 (15%)
 Frame = -2

Query: 52  NFSIIAHVDHGKSTLADRLLELTGTIDK----------------TKKNKQVLDKLQVERE 95
           N  +I HVD GKST    L+   G IDK                + K   VLDKL+ ERE
Sbjct: 883 NIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAQEMGKGSFKYAWVLDKLKAERE 704

Query: 96  RGITVKAQTASLFYSFGGKQYLLNLIDTPGHVDFSYEVSRSLSACQGVLLVVDANEG--- 152
           RGIT+        + F   +Y + +ID PGH DF   +    S     +L+V +  G   
Sbjct: 703 RGITIDIA----LWKFETTKYYVTIIDAPGHRDFIKNMITGTSQADCAVLIVASGTGEFE 536

Query: 153 ----IQAQTVANFFLAFEAQL-SVIPVINKID 179
                + QT  +  LA+   +  +I  +NK+D
Sbjct: 535 AGISKEGQTREHALLAYTLGVKQLIIGVNKMD 440
>15991
          Length = 1629

 Score = 52.4 bits (124), Expect = 5e-07,   Method: Compositional matrix adjust.
 Identities = 36/106 (33%), Positives = 51/106 (48%), Gaps = 8/106 (7%)
 Frame = -3

Query: 82   KNKQVLDKLQVERERGITVKAQTASLFYSFGGKQYLLNLIDTPGHVDFSYEVSRSLSACQ 141
            K   VLDKL+ ERERGIT+        + F   +Y + +ID PGH DF   +    S   
Sbjct: 1513 KYAWVLDKLKAERERGITIDIA----LWKFETDKYYVTIIDAPGHRDFIKNMITGTSQAD 1346

Query: 142  GVLLVVDANEG-------IQAQTVANFFLAFEAQL-SVIPVINKID 179
              +LVV A +G          QT  +  LA+   +  +I  +NK+D
Sbjct: 1345 CAVLVVAAGKGEFEAGISKDGQTREHALLAYTLGVKQLIVAVNKMD 1208
>22349
          Length = 662

 Score = 52.0 bits (123), Expect = 8e-07,   Method: Compositional matrix adjust.
 Identities = 44/138 (31%), Positives = 63/138 (45%), Gaps = 16/138 (11%)
 Frame = -2

Query: 52  NFSIIAHVDHGKSTLADRLLELTGTIDK----------TKKNKQV------LDKLQVERE 95
           N   I HVD GKST+   LL LTG +DK           +KN++       LD    ERE
Sbjct: 487 NVVFIGHVDAGKSTIGGHLLYLTGMVDKRTLEKYEREAKEKNRETWYLSWALDTNNEERE 308

Query: 96  RGITVKAQTASLFYSFGGKQYLLNLIDTPGHVDFSYEVSRSLSACQGVLLVVDANEGIQA 155
           +G TV+   A  F+    K +   ++D PGH  F   +    S     +LV+ A  G   
Sbjct: 307 KGKTVEVGRA--FFETELKHF--TVLDAPGHKSFVPNMICGASQADLAILVISARRG--- 149

Query: 156 QTVANFFLAFEAQLSVIP 173
               ++FL+ EA+   +P
Sbjct: 148 -EF*DWFLSEEARHVSMP 98
>18903
          Length = 814

 Score = 45.1 bits (105), Expect = 9e-05,   Method: Compositional matrix adjust.
 Identities = 22/68 (32%), Positives = 39/68 (57%)
 Frame = +2

Query: 126 HVDFSYEVSRSLSACQGVLLVVDANEGIQAQTVANFFLAFEAQLSVIPVINKIDLKNADP 185
           HVDF+ EV R+L    G + V+DA+ G++AQT+  +  A    +  +  +NK+D + A  
Sbjct: 2   HVDFTVEVERALRVLDGTVTVLDASAGVEAQTLTVWRQAANYSIPSLVYLNKMDKRGASI 181

Query: 186 ERVGKQIE 193
            R  + ++
Sbjct: 182 HRCLQSLQ 205
>01452
          Length = 1734

 Score = 29.6 bits (65), Expect = 4.0,   Method: Compositional matrix adjust.
 Identities = 13/41 (31%), Positives = 24/41 (58%)
 Frame = +1

Query: 541  NGNMVEELVTVVHREKAYTVGKSICERLKESLPRQLYEIAI 581
            +GN + E +  V R++ + VG +IC + +E   R ++ I I
Sbjct: 985  SGNQIYECIRDVFRQRVH*VGGAICCKTQEKTVRAIFMIFI 1107
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|21312712|ref|NP_080732.1| transcription elongation
factor B (SIII), polypeptide 1 [Mus musculus]
         (112 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

08900                                                                 220   1e-58
08663                                                                 219   3e-58
01267                                                                 147   7e-37
17933                                                                  29   0.57 
08304                                                                  28   0.60 
37228                                                                  27   1.6  
09672                                                                  27   2.7  
13201                                                                  25   5.7  
03041                                                                  25   6.6  
>08900
          Length = 434

 Score =  220 bits (560), Expect = 1e-58,   Method: Compositional matrix adjust.
 Identities = 103/109 (94%), Positives = 106/109 (97%)
 Frame = -3

Query: 4   EEKTYGGCEGPDAMYVKLISSDGHEFIVKREHALTSGTIKAMLSGPGQFAENETNEVNFR 63
           EEK YGGCEGPDAMYVKLISSD HEFIVKR+HALTSGTIKAMLSGPGQF+ENETNE+NFR
Sbjct: 372 EEKVYGGCEGPDAMYVKLISSDEHEFIVKRDHALTSGTIKAMLSGPGQFSENETNEINFR 193

Query: 64  EIPSHVLSKVCMYFTYKVRYTNSSTEIPEFPIAPEIALELLMAANFLDC 112
           EIPSHVL KVCMYFTYKVRYTNSSTEIPEFPIAPEIALELLMAANFLDC
Sbjct: 192 EIPSHVLQKVCMYFTYKVRYTNSSTEIPEFPIAPEIALELLMAANFLDC 46
>08663
          Length = 1266

 Score =  219 bits (557), Expect = 3e-58,   Method: Compositional matrix adjust.
 Identities = 103/109 (94%), Positives = 106/109 (97%)
 Frame = -1

Query: 4    EEKTYGGCEGPDAMYVKLISSDGHEFIVKREHALTSGTIKAMLSGPGQFAENETNEVNFR 63
            EEK YGGCEGPDAMYVKLISSD HEFIVKR+HALTSGTIKAMLSGPGQF+ENETNE+NFR
Sbjct: 1113 EEKVYGGCEGPDAMYVKLISSDEHEFIVKRDHALTSGTIKAMLSGPGQFSENETNEINFR 934

Query: 64   EIPSHVLSKVCMYFTYKVRYTNSSTEIPEFPIAPEIALELLMAANFLDC 112
            EIPSHVL KVCMYFTYKVRYTNSSTEIPEFPIAPEIALELLMAANFLDC
Sbjct: 933  EIPSHVLQKVCMYFTYKVRYTNSSTEIPEFPIAPEIALELLMAANFLDC 787
>01267
          Length = 2179

 Score =  147 bits (372), Expect = 7e-37,   Method: Compositional matrix adjust.
 Identities = 69/72 (95%), Positives = 71/72 (98%)
 Frame = +2

Query: 41  TIKAMLSGPGQFAENETNEVNFREIPSHVLSKVCMYFTYKVRYTNSSTEIPEFPIAPEIA 100
           TIKAMLSGPGQF+ENETNE+NFREIPSHVL KVCMYFTYKVRYTNSSTEIPEFPIAPEIA
Sbjct: 2   TIKAMLSGPGQFSENETNEINFREIPSHVLQKVCMYFTYKVRYTNSSTEIPEFPIAPEIA 181

Query: 101 LELLMAANFLDC 112
           LELLMAANFLDC
Sbjct: 182 LELLMAANFLDC 217
>17933
          Length = 842

 Score = 28.9 bits (63), Expect = 0.57,   Method: Compositional matrix adjust.
 Identities = 12/26 (46%), Positives = 16/26 (61%)
 Frame = +2

Query: 55  NETNEVNFREIPSHVLSKVCMYFTYK 80
           ++T     R +P+ VLS  C YFTYK
Sbjct: 212 DKTVSCTLRWLPASVLSLPCDYFTYK 289
>08304
          Length = 2286

 Score = 28.5 bits (62), Expect = 0.60,   Method: Compositional matrix adjust.
 Identities = 11/19 (57%), Positives = 14/19 (73%)
 Frame = -2

Query: 59 EVNFREIPSHVLSKVCMYF 77
          ++ + EIPS VLS VC YF
Sbjct: 83 QIKWSEIPSPVLSSVCTYF 27
>37228
          Length = 453

 Score = 27.3 bits (59), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 11/18 (61%), Positives = 13/18 (72%)
 Frame = -1

Query: 24  SDGHEFIVKREHALTSGT 41
           S GH+FI+ R H L SGT
Sbjct: 186 SAGHDFILHRMHILRSGT 133
>09672
          Length = 1963

 Score = 26.6 bits (57), Expect = 2.7,   Method: Composition-based stats.
 Identities = 10/26 (38%), Positives = 16/26 (61%)
 Frame = +1

Query: 16  AMYVKLISSDGHEFIVKREHALTSGT 41
           A+  ++I    HEFI +R+H  T G+
Sbjct: 895 ALITQVIQEHHHEFIAERQHLETQGS 972
>13201
          Length = 451

 Score = 25.4 bits (54), Expect = 5.7,   Method: Compositional matrix adjust.
 Identities = 12/42 (28%), Positives = 19/42 (45%)
 Frame = -3

Query: 24  SDGHEFIVKREHALTSGTIKAMLSGPGQFAENETNEVNFREI 65
           SDGHE    R    TSG     +  P  +  N T++   +++
Sbjct: 194 SDGHENPALRSQTFTSGVSYVHIVLPDSWGRNHTDQQQSQQV 69
>03041
          Length = 1288

 Score = 25.4 bits (54), Expect = 6.6,   Method: Composition-based stats.
 Identities = 8/16 (50%), Positives = 15/16 (93%)
 Frame = +1

Query: 27  HEFIVKREHALTSGTI 42
           +++I+ +EHALT+GT+
Sbjct: 838 NQYIIGKEHALTNGTL 885
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|82942836|ref|XP_286452.5| PREDICTED: echinoderm
microtubule associated protein like 5 isoform 1 [Mus musculus]
         (1977 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

18461                                                                 225   1e-58
27525                                                                  59   3e-14
02090                                                                  49   2e-05
19949                                                                  49   2e-05
30256                                                                  49   3e-05
13335                                                                  48   5e-05
35607                                                                  47   7e-05
03387                                                                  46   2e-04
12574                                                                  45   2e-04
17598                                                                  45   3e-04
21105                                                                  44   7e-04
15972                                                                  43   0.001
17807                                                                  43   0.002
12806                                                                  40   0.007
01598                                                                  40   0.009
29912                                                                  40   0.012
16199                                                                  40   0.013
37180                                                                  39   0.015
13278                                                                  39   0.026
34005                                                                  38   0.051
21921                                                                  37   0.069
00561                                                                  37   0.072
21960                                                                  37   0.076
03395                                                                  37   0.085
17602                                                                  37   0.087
18981                                                                  37   0.10 
20662                                                                  37   0.11 
35695                                                                  37   0.11 
15118                                                                  36   0.14 
10264                                                                  35   0.31 
14500                                                                  35   0.31 
11678                                                                  34   0.51 
01768                                                                  34   0.70 
15337                                                                  33   0.90 
26107                                                                  33   0.98 
01249                                                                  33   1.0  
20271                                                                  33   1.1  
27465                                                                  33   1.7  
03426                                                                  33   1.7  
15780                                                                  32   2.0  
14555                                                                  32   2.6  
02147                                                                  32   2.9  
09883                                                                  31   3.9  
00825                                                                  30   7.0  
26939                                                                  30   7.3  
>18461
          Length = 456

 Score =  225 bits (573), Expect = 1e-58,   Method: Compositional matrix adjust.
 Identities = 103/152 (67%), Positives = 127/152 (83%)
 Frame = +1

Query: 1053 KALAVGLNDGSFLMANADTLEDLVSFHHRKDIISDIRFSPGSGKYLAVASHDSFVDIYNV 1112
            KALAVGL DGSF++ N++TLE++  FHHRK+ ISDI+FSP  GKYLAVASHD+FVD+Y+V
Sbjct: 1    KALAVGLKDGSFVVLNSETLEEIAGFHHRKEEISDIKFSPDVGKYLAVASHDNFVDLYSV 180

Query: 1113 TSSKRVGVCKGATSYITHIDWDSRGKLLQVNTGAKEQLFFEAPRGKRQTIPSVEVEKISW 1172
               KRVG CKGA+SYITHIDWD+RGK+L VN+GAKEQLFFEAPRGKR T+ + E+EK +W
Sbjct: 181  AGVKRVGTCKGASSYITHIDWDTRGKVLMVNSGAKEQLFFEAPRGKRITLRNTEIEKFNW 360

Query: 1173 ATWTSVLGLCCEGIWPVIGEVTEVTASCLTSD 1204
            A+WT VLG+ CEG+WP   +VT+V AS L  D
Sbjct: 361  ASWTCVLGVTCEGVWPAKSDVTDVNASSLAPD 456

 Score =  137 bits (345), Expect = 4e-32,   Method: Compositional matrix adjust.
 Identities = 66/145 (45%), Positives = 96/145 (66%), Gaps = 2/145 (1%)
 Frame = +1

Query: 381 LALGMKDGSFTVLRVRDMTEVVHIKDRKEAIHELKYSPD-GAYLAVGCNDSSVDIYGVAQ 439
           LA+G+KDGSF VL    + E+     RKE I ++K+SPD G YLAV  +D+ VD+Y VA 
Sbjct: 7   LAVGLKDGSFVVLNSETLEEIAGFHHRKEEISDIKFSPDVGKYLAVASHDNFVDLYSVAG 186

Query: 440 RYKKVGECVGSLSFITHLDWSSDSRYLQTNDGSGKRLLYKMPGGKEVTSKE-EIKGMHWA 498
             K+VG C G+ S+ITH+DW +  + L  N G+ ++L ++ P GK +T +  EI+  +WA
Sbjct: 187 -VKRVGTCKGASSYITHIDWDTRGKVLMVNSGAKEQLFFEAPRGKRITLRNTEIEKFNWA 363

Query: 499 SWTCVAGLEVNGIWPKYSDINDINS 523
           SWTCV G+   G+WP  SD+ D+N+
Sbjct: 364 SWTCVLGVTCEGVWPAKSDVTDVNA 438

 Score = 92.8 bits (229), Expect = 1e-18,   Method: Compositional matrix adjust.
 Identities = 48/151 (31%), Positives = 85/151 (56%), Gaps = 2/151 (1%)
 Frame = +1

Query: 1758 VAIGMKNGEFIILLVSSLKIWGKKRDRRCAIHDIRFSPD-SRYLAVGSSENSVDFYDLTL 1816
            +A+G+K+G F++L   +L+       R+  I DI+FSPD  +YLAV S +N VD Y +  
Sbjct: 7    LAVGLKDGSFVVLNSETLEEIAGFHHRKEEISDIKFSPDVGKYLAVASHDNFVDLYSVA- 183

Query: 1817 GPTLNRISYCKDIPSFVIQMDFSADSRHLQVSSGCYKRHVYEVPSGKHL-VDHAAIDRIT 1875
               + R+  CK   S++  +D+    + L V+SG  ++  +E P GK + + +  I++  
Sbjct: 184  --GVKRVGTCKGASSYITHIDWDTRGKVLMVNSGAKEQLFFEAPRGKRITLRNTEIEKFN 357

Query: 1876 WATWTSILGDEVMGIWSRHAEKADVTCACVS 1906
            WA+WT +LG    G+W   ++  DV  + ++
Sbjct: 358  WASWTCVLGVTCEGVWPAKSDVTDVNASSLA 450
>27525
          Length = 828

 Score = 56.2 bits (134), Expect(2) = 3e-14,   Method: Compositional matrix adjust.
 Identities = 39/119 (32%), Positives = 59/119 (49%), Gaps = 5/119 (4%)
 Frame = +2

Query: 1067 ANADTLEDLVSFHHRKDIISDIRFSPGSGKYLAVASHDSFVDIYNVTSSKRVGVCKGA-- 1124
             + D  E   SF   +  I+ I FSP  G  LAV  HD FV +Y V     V   K A  
Sbjct: 23   GDMDGREPRNSFQVGQAQINAISFSP-DGSQLAVGCHDGFVHVYVVHEDGLVFRQKSAAL 199

Query: 1125 ---TSYITHIDWDSRGKLLQVNTGAKEQLFFEAPRGKRQTIPSVEVEKISWATWTSVLG 1180
               +++I H+DW S  + LQ   G  E +F+E    K+Q+     +  ++W+T++S +G
Sbjct: 200  RYNSTFIMHLDWSSDCRYLQCTLGDYELVFWEVQNMKKQS--GRALRDVNWSTFSSPVG 370

 Score = 42.4 bits (98), Expect(2) = 3e-14,   Method: Composition-based stats.
 Identities = 22/80 (27%), Positives = 41/80 (51%)
 Frame = +3

Query: 1185 GIWPVIGEVTEVTASCLTSDKMVLATGDDLGFVKLFRYPAKGKFGKFKKYVAHSTHVTNV 1244
            G W ++     +  +C +     + TGD  G ++LF+YP+ G   + ++   +S++ T  
Sbjct: 384  GPWQMMERGEVINMACRSKYLDFILTGDSRGRIRLFKYPSTGSKVECQETKPYSSNTTAA 563

Query: 1245 RWTYDDSMLVTLGGADMSLM 1264
                DDS ++  GG D +LM
Sbjct: 564  EILSDDSGILVSGGRDAALM 623

 Score = 59.3 bits (142), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 35/103 (33%), Positives = 58/103 (56%), Gaps = 5/103 (4%)
 Frame = +2

Query: 408 KEAIHELKYSPDGAYLAVGCNDSSVDIY-----GVAQRYKKVGECVGSLSFITHLDWSSD 462
           +  I+ + +SPDG+ LAVGC+D  V +Y     G+  R K       S +FI HLDWSSD
Sbjct: 68  QAQINAISFSPDGSQLAVGCHDGFVHVYVVHEDGLVFRQKSAALRYNS-TFIMHLDWSSD 244

Query: 463 SRYLQTNDGSGKRLLYKMPGGKEVTSKEEIKGMHWASWTCVAG 505
            RYLQ   G  + + +++   K+  S   ++ ++W++++   G
Sbjct: 245 CRYLQCTLGDYELVFWEVQNMKK-QSGRALRDVNWSTFSSPVG 370

 Score = 43.5 bits (101), Expect(2) = 3e-08,   Method: Compositional matrix adjust.
 Identities = 31/99 (31%), Positives = 53/99 (53%), Gaps = 2/99 (2%)
 Frame = +2

Query: 1788 IHDIRFSPDSRYLAVGSSENSVDFYDLTLGPTLNR--ISYCKDIPSFVIQMDFSADSRHL 1845
            I+ I FSPD   LAVG  +  V  Y +     + R   +  +   +F++ +D+S+D R+L
Sbjct: 77   INAISFSPDGSQLAVGCHDGFVHVYVVHEDGLVFRQKSAALRYNSTFIMHLDWSSDCRYL 256

Query: 1846 QVSSGCYKRHVYEVPSGKHLVDHAAIDRITWATWTSILG 1884
            Q + G Y+   +EV + K     A  D + W+T++S +G
Sbjct: 257  QCTLGDYELVFWEVQNMKKQSGRALRD-VNWSTFSSPVG 370

 Score = 34.3 bits (77), Expect(2) = 3e-08,   Method: Composition-based stats.
 Identities = 21/92 (22%), Positives = 40/92 (43%)
 Frame = +3

Query: 1882 ILGDEVMGIWSRHAEKADVTCACVSHSGISLVTGDDFGMVKLYDFPCPEKFAKHKRFLGH 1941
            +L   ++G W        +  AC S     ++TGD  G ++L+ +P      + +    +
Sbjct: 363  LLDTPLVGPWQMMERGEVINMACRSKYLDFILTGDSRGRIRLFKYPSTGSKVECQETKPY 542

Query: 1942 SPHVTNIRFTSGDRHVVSAGGDDCSLFVWKCV 1973
            S + T     S D  ++ +GG D +L  +  V
Sbjct: 543  SSNTTAAEILSDDSGILVSGGRDAALMYFALV 638
>02090
          Length = 1841

 Score = 48.9 bits (115), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 46/226 (20%), Positives = 87/226 (38%), Gaps = 1/226 (0%)
 Frame = -3

Query: 1635 KEGGAVKLWDQELRRCRAFRLETGQVTDCVRSVCRGKGKILVGTRNSEIIEVGE-KNAAC 1693
            +E   + +WD      R     T     C        GK+     +   I V +  N   
Sbjct: 1701 REASTLSIWDLATPTPRIKAELTSSAPACYALAISPDGKVCFSCCSDGNIAVWDLHNQTL 1522

Query: 1694 NILVNGHVDGPIWGLATHPSRDFFLSAAEDGTVRLWDIADKKMLNKVNLGHAARTVCYSP 1753
                 GH DG    +   P      +   D TVR WD+ + + L + +      ++ Y P
Sbjct: 1521 VRQFQGHTDGAS-CIDISPDGTKLWTGGLDNTVRSWDLREGRQLQQHDFSSQIFSLGYCP 1345

Query: 1754 EGDMVAIGMKNGEFIILLVSSLKIWGKKRDRRCAIHDIRFSPDSRYLAVGSSENSVDFYD 1813
             G+ +A+GM++    +L  S    +       C +  ++F+   ++      +N ++ + 
Sbjct: 1344 TGEWLAVGMESSNVEVLHHSKPDKYQLHLHESCVL-SLKFAYCGKWFVSTGKDNLLNAWR 1168

Query: 1814 LTLGPTLNRISYCKDIPSFVIQMDFSADSRHLQVSSGCYKRHVYEV 1859
               G ++    +     S V+  D +AD +++   SG  K  +YEV
Sbjct: 1167 TPYGASI----FQSKESSSVLSCDIAADDKYIVTGSGDKKATLYEV 1042

 Score = 41.6 bits (96), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 27/107 (25%), Positives = 49/107 (45%), Gaps = 1/107 (0%)
 Frame = -3

Query: 329  WALAVHPTKPLAVTGSDDRSVRIWSLVDHALIARCN-MEEPIRCAAVNVDGIHLALGMKD 387
            +ALA+ P   +  +   D ++ +W L +  L+ +     +   C  ++ DG  L  G  D
Sbjct: 1614 YALAISPDGKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISPDGTKLWTGGLD 1435

Query: 388  GSFTVLRVRDMTEVVHIKDRKEAIHELKYSPDGAYLAVGCNDSSVDI 434
             +     +R+  ++    D    I  L Y P G +LAVG   S+V++
Sbjct: 1434 NTVRSWDLREGRQLQQ-HDFSSQIFSLGYCPTGEWLAVGMESSNVEV 1297

 Score = 34.3 bits (77), Expect = 0.57,   Method: Compositional matrix adjust.
 Identities = 32/117 (27%), Positives = 56/117 (47%), Gaps = 6/117 (5%)
 Frame = -3

Query: 209  ELTYSGALNGDIYVWKGIN--LIRTIQGAHTAGIFSMNSCEEG--FATGGRDGCIRLWDL 264
            ++ +S   +G+I VW   N  L+R  QG HT G   ++   +G    TGG D  +R WDL
Sbjct: 1587 KVCFSCCSDGNIAVWDLHNQTLVRQFQG-HTDGASCIDISPDGTKLWTGGLDNTVRSWDL 1411

Query: 265  TFKPITVIDLRETEQGYKGLSVRSV--CWRGDHILVGTQDSEIFEIVVHERNKPFLI 319
                    + R+ +Q      + S+  C  G+ + VG + S + E++ H +   + +
Sbjct: 1410 R-------EGRQLQQHDFSSQIFSLGYCPTGEWLAVGMESSNV-EVLHHSKPDKYQL 1264

 Score = 33.5 bits (75), Expect = 0.79,   Method: Compositional matrix adjust.
 Identities = 30/111 (27%), Positives = 46/111 (41%), Gaps = 3/111 (2%)
 Frame = -3

Query: 1002 WGLATHPYLPICATVSDDKTLRIWDLSPSHCMLAVRKLK---KGGRCCCFSPDGKALAVG 1058
            + LA  P   +C +   D  + +WDL   H    VR+ +    G  C   SPDG  L  G
Sbjct: 1614 YALAISPDGKVCFSCCSDGNIAVWDL---HNQTLVRQFQGHTDGASCIDISPDGTKLWTG 1444

Query: 1059 LNDGSFLMANADTLEDLVSFHHRKDIISDIRFSPGSGKYLAVASHDSFVDI 1109
              D +    +      L        I S + + P +G++LAV    S V++
Sbjct: 1443 GLDNTVRSWDLREGRQLQQHDFSSQIFS-LGYCP-TGEWLAVGMESSNVEV 1297
>19949
          Length = 903

 Score = 48.9 bits (115), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 33/110 (30%), Positives = 54/110 (49%), Gaps = 2/110 (1%)
 Frame = +2

Query: 1707 GLATHPSRDFFLSAAEDGTVRLWDIADKKMLNKVNLGHAARTVC--YSPEGDMVAIGMKN 1764
             L  HP   +  S + D  V+LWDI  K  +     GH     C  +SP+G  +A   ++
Sbjct: 8    SLDFHPYGAYTASGSMDCNVKLWDIRRKGCIYTYK-GHTGCVCCLRFSPDGRWIASASED 184

Query: 1765 GEFIILLVSSLKIWGKKRDRRCAIHDIRFSPDSRYLAVGSSENSVDFYDL 1814
            G   +  +++ K+    +  R A++ I F P    LA GS++ +V F+DL
Sbjct: 185  GLVKLWDLTAGKLLTDLKLHRDAVNTIEFHPHEFLLASGSADRTVKFWDL 334

 Score = 43.5 bits (101), Expect = 8e-04,   Method: Compositional matrix adjust.
 Identities = 40/151 (26%), Positives = 66/151 (43%), Gaps = 1/151 (0%)
 Frame = +2

Query: 1001 VWGLATHPYLPICATVSDDKTLRIWDLSPSHCMLAVRKLKKGGRCCC-FSPDGKALAVGL 1059
            V  L  HPY    A+ S D  +++WD+    C+    K   G  CC  FSPDG+ +A   
Sbjct: 2    VKSLDFHPYGAYTASGSMDCNVKLWDIRRKGCIYTY-KGHTGCVCCLRFSPDGRWIASAS 178

Query: 1060 NDGSFLMANADTLEDLVSFHHRKDIISDIRFSPGSGKYLAVASHDSFVDIYNVTSSKRVG 1119
             DG   + +    + L      +D ++ I F P     LA  S D  V  +++ + + + 
Sbjct: 179  EDGLVKLWDLTAGKLLTDLKLHRDAVNTIEFHPHEF-LLASGSADRTVKFWDLETFQLIS 355

Query: 1120 VCKGATSYITHIDWDSRGKLLQVNTGAKEQL 1150
              +   + I  I +   G  L   +G+K+ L
Sbjct: 356  TTEPEANSIRSILFHPDGVCLY--SGSKDTL 442

 Score = 42.0 bits (97), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 31/119 (26%), Positives = 50/119 (42%), Gaps = 1/119 (0%)
 Frame = +2

Query: 1689 KNAACNILVNGHVDGPIWGLATHPSRDFFLSAAEDGTVRLWDIADKKMLNKVNLGH-AAR 1747
            +   C     GH  G +  L   P   +  SA+EDG V+LWD+   K+L  + L   A  
Sbjct: 83   RRKGCIYTYKGHT-GCVCCLRFSPDGRWIASASEDGLVKLWDLTAGKLLTDLKLHRDAVN 259

Query: 1748 TVCYSPEGDMVAIGMKNGEFIILLVSSLKIWGKKRDRRCAIHDIRFSPDSRYLAVGSSE 1806
            T+ + P   ++A G  +       + + ++         +I  I F PD   L  GS +
Sbjct: 260  TIEFHPHEFLLASGSADRTVKFWDLETFQLISTTEPEANSIRSILFHPDGVCLYSGSKD 436

 Score = 37.0 bits (84), Expect = 0.071,   Method: Compositional matrix adjust.
 Identities = 30/116 (25%), Positives = 50/116 (43%)
 Frame = +2

Query: 64  IISLALHPERVLVATGQVGKEPYICVWDSYTVQTVSVLKDVHTHGIACLAFDLDGQRLVS 123
           + SL  HP     A+G +  +  + +WD      +   K  HT  + CL F  DG+ + S
Sbjct: 2   VKSLDFHPYGAYTASGSM--DCNVKLWDIRRKGCIYTYKG-HTGCVCCLRFSPDGRWIAS 172

Query: 124 VGLDSKNAVCVWDWKRGRMLSMAPGHTDRIFDISWDLYQPNKLVSCGVKHIKFWSL 179
              D    V +WD   G++L+    H D +  I +  ++         + +KFW L
Sbjct: 173 ASED--GLVKLWDLTAGKLLTDLKLHRDAVNTIEFHPHEFLLASGSADRTVKFWDL 334

 Score = 35.8 bits (81), Expect = 0.19,   Method: Compositional matrix adjust.
 Identities = 21/59 (35%), Positives = 29/59 (49%), Gaps = 1/59 (1%)
 Frame = +2

Query: 330 ALAVHPTKPLAVTGSDDRSVRIWSLVDHALIARCNME-EPIRCAAVNVDGIHLALGMKD 387
            +  HP + L  +GS DR+V+ W L    LI+    E   IR    + DG+ L  G KD
Sbjct: 260 TIEFHPHEFLLASGSADRTVKFWDLETFQLISTTEPEANSIRSILFHPDGVCLYSGSKD 436

 Score = 33.1 bits (74), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 15/38 (39%), Positives = 22/38 (57%)
 Frame = +2

Query: 1791 IRFSPDSRYLAVGSSENSVDFYDLTLGPTLNRISYCKD 1828
            +RFSPD R++A  S +  V  +DLT G  L  +   +D
Sbjct: 137  LRFSPDGRWIASASEDGLVKLWDLTAGKLLTDLKLHRD 250

 Score = 32.0 bits (71), Expect = 2.8,   Method: Compositional matrix adjust.
 Identities = 22/79 (27%), Positives = 37/79 (46%)
 Frame = +2

Query: 60  HSDDIISLALHPERVLVATGQVGKEPYICVWDSYTVQTVSVLKDVHTHGIACLAFDLDGQ 119
           H D + ++  HP   L+A+G   +   +  WD  T Q +S   +   + I  + F  DG 
Sbjct: 242 HRDAVNTIEFHPHEFLLASGSADRT--VKFWDLETFQLIST-TEPEANSIRSILFHPDGV 412

Query: 120 RLVSVGLDSKNAVCVWDWK 138
            L S    SK+ + V+ W+
Sbjct: 413 CLYS---GSKDTLKVYHWE 460

 Score = 31.2 bits (69), Expect = 4.3,   Method: Compositional matrix adjust.
 Identities = 25/112 (22%), Positives = 52/112 (46%), Gaps = 4/112 (3%)
 Frame = +2

Query: 330 ALAVHPTKPLAVTGSDDRSVRIWSLVDHALIARCNMEEP-IRCAAVNVDGIHLALGMKDG 388
           +L  HP      +GS D +V++W +     I         + C   + DG  +A   +DG
Sbjct: 8   SLDFHPYGAYTASGSMDCNVKLWDIRRKGCIYTYKGHTGCVCCLRFSPDGRWIASASEDG 187

Query: 389 SFTVLRVRDMTE---VVHIKDRKEAIHELKYSPDGAYLAVGCNDSSVDIYGV 437
              ++++ D+T    +  +K  ++A++ +++ P    LA G  D +V  + +
Sbjct: 188 ---LVKLWDLTAGKLLTDLKLHRDAVNTIEFHPHEFLLASGSADRTVKFWDL 334
>30256
          Length = 961

 Score = 48.5 bits (114), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 53/212 (25%), Positives = 95/212 (44%), Gaps = 6/212 (2%)
 Frame = +3

Query: 59  GHSDDIISLALHPERVLVATGQVGKEPYICVWDSYTVQTVSVLKDVHTHGIACLAFDLDG 118
           GHS  +  L+L  ++V+  +    ++  + VWD  +   ++VL   H   + C+ +D  G
Sbjct: 156 GHSSTVRCLSLSGKKVVSGS----RDATLRVWDIESGHCLNVLLG-HMAAVRCVQYD--G 314

Query: 119 QRLVSVGLDSKNAVCVWDWKRGRMLSMAPGHTDRIFDISWD-LYQPNKLVSCGVKHIKFW 177
           +R+VS   D    V VWD      L    GHT+R++ + +D +Y  +  +      I+ W
Sbjct: 315 KRVVSGAXDY--TVRVWDPDTASCLHTLQGHTNRVYSLQFDGVYVVSGSLD---TSIRVW 479

Query: 178 SL-CGNALTPKRGVFGKTGDLQTILCLACARDELTYSGALNGDIYVWK--GINLIRTIQG 234
            + CG  +    G    T  L+        +D L  SG  +  + VW       ++T+ G
Sbjct: 480 DVRCGKLVHTLMGHQSLTSGLE-------LKDNLLVSGNADSTVKVWDVHTGKCLQTLLG 638

Query: 235 --AHTAGIFSMNSCEEGFATGGRDGCIRLWDL 264
              H + +  +   ++   T   DG ++LWDL
Sbjct: 639 PNKHRSAVTCLQFNKKFVVTCSDDGTVKLWDL 734

 Score = 43.9 bits (102), Expect = 6e-04,   Method: Compositional matrix adjust.
 Identities = 39/163 (23%), Positives = 67/163 (41%), Gaps = 10/163 (6%)
 Frame = +3

Query: 1017 SDDKTLRIWDLSPSHCMLAVRKLKKGGRCCCFSPDGKALAVGLNDGSFLMANADTLEDLV 1076
            S D TLR+WD+   HC+  +       RC  +  DGK +  G  D +  + + DT   L 
Sbjct: 213  SRDATLRVWDIESGHCLNVLLGHMAAVRCVQY--DGKRVVSGAXDYTVRVWDPDTASCLH 386

Query: 1077 SFHHRKDIISDIRFSPGSGKYLAVASHDSFVDIYNVTSSKRVGVCKGATSYITHIDW--- 1133
            +     + +  ++F    G Y+   S D+ + +++V   K V    G  S  + ++    
Sbjct: 387  TLQGHTNRVYSLQF---DGVYVVSGSLDTSIRVWDVRCGKLVHTLMGHQSLTSGLELKDN 557

Query: 1134 -------DSRGKLLQVNTGAKEQLFFEAPRGKRQTIPSVEVEK 1169
                   DS  K+  V+TG   Q     P   R  +  ++  K
Sbjct: 558  LLVSGNADSTVKVWDVHTGKCLQTLL-GPNKHRSAVTCLQFNK 683

 Score = 34.7 bits (78), Expect = 0.36,   Method: Compositional matrix adjust.
 Identities = 40/145 (27%), Positives = 64/145 (44%), Gaps = 3/145 (2%)
 Frame = +3

Query: 213 SGALNGDIYVWK--GINLIRTIQGAHTAGIFSMNSCEEGFATGGRDGCIRLWDLTFKPIT 270
           SGA +  + VW     + + T+QG HT  ++S+        +G  D  IR+WD+    + 
Sbjct: 327 SGAXDYTVRVWDPDTASCLHTLQG-HTNRVYSLQFDGVYVVSGSLDTSIRVWDVRCGKL- 500

Query: 271 VIDLRETEQGYKGLSVRSVCWRGDHILV-GTQDSEIFEIVVHERNKPFLIMQGHCEGELW 329
           V  L   +    GL ++      D++LV G  DS +    VH   K    + G  +    
Sbjct: 501 VHTLMGHQSLTSGLELK------DNLLVSGNADSTVKVWDVHT-GKCLQTLLGPNKHRSA 659

Query: 330 ALAVHPTKPLAVTGSDDRSVRIWSL 354
              +   K   VT SDD +V++W L
Sbjct: 660 VTCLQFNKKFVVTCSDDGTVKLWDL 734
>13335
          Length = 863

 Score = 47.8 bits (112), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 50/211 (23%), Positives = 81/211 (38%), Gaps = 21/211 (9%)
 Frame = +1

Query: 213 SGALNGDIYVWK------------------GINLIRTIQGAHTAGIFSMNSCEEGFATGG 254
           SG+ NGD+YVW                   G+          TA   + ++C    ATGG
Sbjct: 238 SGSPNGDLYVWDASFGHCRHLTLRVDAHDLGVTCCEFSPTFGTACAENSSTCNLLLATGG 417

Query: 255 RDGCIRLWDLTFKPITVIDLRETEQGYKGLSVRSVCWRGDHILVGTQDSEIFEIVVHERN 314
           +D  I+LW  + +                              VG+      E+ +  R+
Sbjct: 418 KDNLIKLWTFSAQ------------------------------VGSP-----EVTLQCRD 492

Query: 315 KPFLIMQGHCEGELWALAVHPTKPLAVTGSDDRSVRIWSLVDHAL---IARCNMEEPIRC 371
               I+ GH +  + A A  P+  L  +GS D+SVR+W  V       I  C+    + C
Sbjct: 493 ----ILSGHSD-LVMACAFSPSSALLASGSFDKSVRLWDSVKGVALFSIEACH-SRFVTC 654

Query: 372 AAVNVDGIHLALGMKDGSFTVLRVRDMTEVV 402
            A ++DG  LA G  D    + ++ D + ++
Sbjct: 655 CAFSIDGTLLASGSMDRIIKIWKLTDTSSIM 747

 Score = 47.4 bits (111), Expect = 6e-05,   Method: Compositional matrix adjust.
 Identities = 66/285 (23%), Positives = 94/285 (32%), Gaps = 21/285 (7%)
 Frame = +1

Query: 798  IVLWDWKKGE-KLSVTRGSKDKIFVVKMNPYVPDKLITAGIKHMKFWRRAXXXXXXXXXX 856
            +++WD K G  K      SK  I V K +P     +  +    +  W  A          
Sbjct: 4    VIVWDVKTGSIKGEYQHASKSSIRVCKFSPSSSHLVSGSDDDTICMWEVATQKLVRSY-- 177

Query: 857  XXTLGKNDTMMCAVYGWTEEMAFSGTSTGDVCIWRDVF-----LVKTVKAHD-------- 903
               +G  D++M   Y        SG+  GD+ +W   F     L   V AHD        
Sbjct: 178  ---VGHEDSVMALAYSPNGHYLVSGSPNGDLYVWDASFGHCRHLTLRVDAHDLGVTCCEF 348

Query: 904  GPVFSMHALEKG------FVTGGKDGMVALWDDSFERCLKTYAIKRADLAPGSKGLLLED 957
             P F     E          TGGKD ++ LW  S +               GS  + L+ 
Sbjct: 349  SPTFGTACAENSSTCNLLLATGGKDNLIKLWTFSAQ--------------VGSPEVTLQ- 483

Query: 958  NPSIRAISLGHGHILVGTKNGEILEVDKSGPITLLVQGHMEGEVWGLATHPYLPICATVS 1017
                R I  GH  +                             V   A  P   + A+ S
Sbjct: 484  ---CRDILSGHSDL-----------------------------VMACAFSPSSALLASGS 567

Query: 1018 DDKTLRIWDLSPSHCMLAVRKL-KKGGRCCCFSPDGKALAVGLND 1061
             DK++R+WD      + ++     +   CC FS DG  LA G  D
Sbjct: 568  FDKSVRLWDSVKGVALFSIEACHSRFVTCCAFSIDGTLLASGSMD 702

 Score = 43.9 bits (102), Expect = 6e-04,   Method: Compositional matrix adjust.
 Identities = 29/91 (31%), Positives = 43/91 (47%), Gaps = 2/91 (2%)
 Frame = +1

Query: 39  FVAGVGVVYSPREHRQ--KFFRGHSDDIISLALHPERVLVATGQVGKEPYICVWDSYTVQ 96
           F A VG   SP    Q      GHSD +++ A  P   L+A+G   K   + +WDS    
Sbjct: 445 FSAQVG---SPEVTLQCRDILSGHSDLVMACAFSPSSALLASGSFDKS--VRLWDSVKGV 609

Query: 97  TVSVLKDVHTHGIACLAFDLDGQRLVSVGLD 127
            +  ++  H+  + C AF +DG  L S  +D
Sbjct: 610 ALFSIEACHSRFVTCCAFSIDGTLLASGSMD 702

 Score = 37.7 bits (86), Expect = 0.043,   Method: Compositional matrix adjust.
 Identities = 55/241 (22%), Positives = 95/241 (39%), Gaps = 26/241 (10%)
 Frame = +1

Query: 1712 PSRDFFLSAAEDGTVRLWDIADKKMLNKVNLGH--AARTVCYSPEGDMVAIGMKNGEFII 1769
            PS    +S ++D T+ +W++A +K++ +  +GH  +   + YSP G  +  G  NG+  +
Sbjct: 91   PSSSHLVSGSDDDTICMWEVATQKLV-RSYVGHEDSVMALAYSPNGHYLVSGSPNGDLYV 267

Query: 1770 LLVSSLKIWGKKR--DRRCAIHDI-----RFSPD------------SRYLAVGSSENSVD 1810
               S    +G  R    R   HD+      FSP             +  LA G  +N + 
Sbjct: 268  WDAS----FGHCRHLTLRVDAHDLGVTCCEFSPTFGTACAENSSTCNLLLATGGKDNLIK 435

Query: 1811 FYDLTLGPTLNRISY-CKDIPS----FVIQMDFSADSRHLQVSSGCYKRHVYEVPSGKHL 1865
             +  +       ++  C+DI S     V+   FS  S  L  +SG + + V         
Sbjct: 436  LWTFSAQVGSPEVTLQCRDILSGHSDLVMACAFSPSSALL--ASGSFDKSVR-------- 585

Query: 1866 VDHAAIDRITWATWTSILGDEVMGIWSRHAEKADVTCACVSHSGISLVTGDDFGMVKLYD 1925
                         W S+ G  +  I + H+    VTC   S  G  L +G    ++K++ 
Sbjct: 586  ------------LWDSVKGVALFSIEACHSRF--VTCCAFSIDGTLLASGSMDRIIKIWK 723

Query: 1926 F 1926
             
Sbjct: 724  L 726

 Score = 36.6 bits (83), Expect = 0.099,   Method: Compositional matrix adjust.
 Identities = 46/203 (22%), Positives = 78/203 (38%), Gaps = 27/203 (13%)
 Frame = +1

Query: 1586 TGTISGDVCVWKDHILCRVVARA---HNGPVFAMYTTLRDGLIVTGGKERPSKEGGAVKL 1642
            +G+    +C+W+  +  + + R+   H   V A+  +     +V+G         G + +
Sbjct: 112  SGSDDDTICMWE--VATQKLVRSYVGHEDSVMALAYSPNGHYLVSGSPN------GDLYV 267

Query: 1643 WDQELRRCRAFRLETGQ----VTDCVRSVCRGKG--------KILVGTRNSEII------ 1684
            WD     CR   L        VT C  S   G           +L+ T   + +      
Sbjct: 268  WDASFGHCRHLTLRVDAHDLGVTCCEFSPTFGTACAENSSTCNLLLATGGKDNLIKLWTF 447

Query: 1685 --EVG--EKNAACNILVNGHVDGPIWGLATHPSRDFFLSAAEDGTVRLWDIADKKMLNKV 1740
              +VG  E    C  +++GH D  +   A  PS     S + D +VRLWD      L  +
Sbjct: 448  SAQVGSPEVTLQCRDILSGHSD-LVMACAFSPSSALLASGSFDKSVRLWDSVKGVALFSI 624

Query: 1741 NLGHAARTVC--YSPEGDMVAIG 1761
               H+    C  +S +G ++A G
Sbjct: 625  EACHSRFVTCCAFSIDGTLLASG 693

 Score = 36.2 bits (82), Expect = 0.12,   Method: Compositional matrix adjust.
 Identities = 20/67 (29%), Positives = 33/67 (49%), Gaps = 2/67 (2%)
 Frame = +1

Query: 717 QNTQRFYLGHDDDILCLAIHPLKDYVATGQVGRDPSIHVWDTET--IKPLSILKGYHQYG 774
           Q   R Y+GH+D ++ LA  P   Y+ +G    D  ++VWD      + L++    H  G
Sbjct: 157 QKLVRSYVGHEDSVMALAYSPNGHYLVSGSPNGD--LYVWDASFGHCRHLTLRVDAHDLG 330

Query: 775 ICAVDFS 781
           +   +FS
Sbjct: 331 VTCCEFS 351

 Score = 35.4 bits (80), Expect = 0.22,   Method: Compositional matrix adjust.
 Identities = 21/69 (30%), Positives = 32/69 (46%)
 Frame = +1

Query: 725 GHDDDILCLAIHPLKDYVATGQVGRDPSIHVWDTETIKPLSILKGYHQYGICAVDFSADG 784
           GH D ++  A  P    +A+G    D S+ +WD+     L  ++  H   +    FS DG
Sbjct: 502 GHSDLVMACAFSPSSALLASGSF--DKSVRLWDSVKGVALFSIEACHSRFVTCCAFSIDG 675

Query: 785 KRLASVGID 793
             LAS  +D
Sbjct: 676 TLLASGSMD 702

 Score = 32.3 bits (72), Expect = 1.8,   Method: Compositional matrix adjust.
 Identities = 19/61 (31%), Positives = 30/61 (49%)
 Frame = +1

Query: 1457 SVHIWDAVNKQTLSILRCSHSKGVCSVSFSATGKLLLSVGLDPEHTVTIWRWQEGAKIAS 1516
            SV +WD+V    L  +   HS+ V   +FS  G LL S  +D    + IW+  + + I  
Sbjct: 577  SVRLWDSVKGVALFSIEACHSRFVTCCAFSIDGTLLASGSMD--RIIKIWKLTDTSSIMG 750

Query: 1517 R 1517
            +
Sbjct: 751  K 753

 Score = 31.6 bits (70), Expect = 3.0,   Method: Compositional matrix adjust.
 Identities = 56/244 (22%), Positives = 96/244 (39%), Gaps = 17/244 (6%)
 Frame = +1

Query: 1040 KKGGRCCCFSPDGKALAVGLNDGSFLMANADTLEDLVSFHHRKDIISDIRFSPGSGKYLA 1099
            K   R C FSP    L  G +D +  M    T + + S+   +D +  + +SP +G YL 
Sbjct: 61   KSSIRVCKFSPSSSHLVSGSDDDTICMWEVATQKLVRSYVGHEDSVMALAYSP-NGHYLV 237

Query: 1100 VASHDSFVDIYNVT-----------SSKRVGV--CKGATSYITHIDWDSRGKLLQVNTGA 1146
              S +  + +++ +            +  +GV  C+ + ++ T    +S    L + TG 
Sbjct: 238  SGSPNGDLYVWDASFGHCRHLTLRVDAHDLGVTCCEFSPTFGTACAENSSTCNLLLATGG 417

Query: 1147 KEQLF----FEAPRGKRQTIPSVEVEKISWATWTSVLGLCCEGIWPVIGEVTEVTASCLT 1202
            K+ L     F A  G     P V ++              C  I  + G    V A   +
Sbjct: 418  KDNLIKLWTFSAQVGS----PEVTLQ--------------CRDI--LSGHSDLVMACAFS 537

Query: 1203 SDKMVLATGDDLGFVKLFRYPAKGKFGKFKKYVAHSTHVTNVRWTYDDSMLVTLGGADMS 1262
                +LA+G     V+L+    KG    F     HS  VT   ++ D ++L + G  D  
Sbjct: 538  PSSALLASGSFDKSVRLWD-SVKG-VALFSIEACHSRFVTCCAFSIDGTLLAS-GSMDRI 708

Query: 1263 LMVW 1266
            + +W
Sbjct: 709  IKIW 720
>35607
          Length = 475

 Score = 47.0 bits (110), Expect = 7e-05,   Method: Compositional matrix adjust.
 Identities = 31/137 (22%), Positives = 63/137 (45%)
 Frame = +2

Query: 1723 DGTVRLWDIADKKMLNKVNLGHAARTVCYSPEGDMVAIGMKNGEFIILLVSSLKIWGKKR 1782
            D TVR WD+ + + L + +      ++ Y P GD +A+GM++    +L  S    +    
Sbjct: 41   DNTVRSWDLREGRQLQQHDFSSQIFSLGYCPTGDWLAVGMESSNVEVLHHSKPDKYQLHL 220

Query: 1783 DRRCAIHDIRFSPDSRYLAVGSSENSVDFYDLTLGPTLNRISYCKDIPSFVIQMDFSADS 1842
               C +  ++F+   ++      +N ++ +    G ++    +     S V+  D +AD 
Sbjct: 221  HESCVL-SLKFAYCGKWFVSTGKDNLLNAWRTPYGASI----FQSKESSSVLSCDIAADD 385

Query: 1843 RHLQVSSGCYKRHVYEV 1859
            +++   SG  K  +YEV
Sbjct: 386  KYIVTGSGDKKATLYEV 436
>03387
          Length = 1891

 Score = 45.8 bits (107), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 35/130 (26%), Positives = 58/130 (44%), Gaps = 6/130 (4%)
 Frame = +1

Query: 56  FFRGHSDDIISLALH--PERVLVATGQVGKEPYICVWD--SYTVQTVSVLKDVHTHGIAC 111
            F GH+  +  +A H   E +    G V  +  + +WD  S T    S + D HT  + C
Sbjct: 496 IFTGHTSVVEDVAWHLLHESLF---GSVADDQKLMIWDTRSNTTSKPSHVVDAHTAEVNC 666

Query: 112 LAFDLDGQRLVSVGLDSKNAVCVWDWKRGRM-LSMAPGHTDRIFDISWDLYQPNKLVSCG 170
           L+F+   + +++ G   K  V +WD +  ++ L     H D IF + W  +    L S G
Sbjct: 667 LSFNPYSEFILATGSADK-TVALWDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSG 843

Query: 171 V-KHIKFWSL 179
             + +  W L
Sbjct: 844 TDRRLHVWDL 873

 Score = 35.8 bits (81), Expect = 0.16,   Method: Compositional matrix adjust.
 Identities = 43/170 (25%), Positives = 78/170 (45%), Gaps = 16/170 (9%)
 Frame = +1

Query: 1706 WGLATHPSRD-FFLSAAEDGTVRLWDIADKKMLNKVNLGHAARTVCYSPEGDMVAIGMKN 1764
            +GL+ +P+ +   LSA++D T+ LWDI   +  ++V   H   T   S   D+    +  
Sbjct: 373  YGLSWNPNLNGHLLSASDDHTICLWDINSTQRESRVVDAHTIFTGHTSVVEDVAWHLLHE 552

Query: 1765 GEF-IILLVSSLKIWGKKRD-----------RRCAIHDIRFSPDSRY-LAVGSSENSVDF 1811
              F  +     L IW  + +               ++ + F+P S + LA GS++ +V  
Sbjct: 553  SLFGSVADDQKLMIWDTRSNTTSKPSHVVDAHTAEVNCLSFNPYSEFILATGSADKTVAL 732

Query: 1812 YDL-TLGPTLNRISYCKDIPSFVIQMDFSADSRHLQVSSGCYKR-HVYEV 1859
            +DL  L   L+     KD    + Q+ +S  +  +  SSG  +R HV+++
Sbjct: 733  WDLRNLKLKLHSFESHKD---EIFQVQWSPHNETILASSGTDRRLHVWDL 873

 Score = 35.0 bits (79), Expect = 0.32,   Method: Compositional matrix adjust.
 Identities = 30/110 (27%), Positives = 51/110 (46%), Gaps = 8/110 (7%)
 Frame = +1

Query: 1012 ICATVSDDKTLRIWDL------SPSHCMLAVRKLKKGGRCCCFSPDGK-ALAVGLNDGSF 1064
            +  +V+DD+ L IWD        PSH    V        C  F+P  +  LA G  D + 
Sbjct: 556  LFGSVADDQKLMIWDTRSNTTSKPSHV---VDAHTAEVNCLSFNPYSEFILATGSADKTV 726

Query: 1065 LMANADTLE-DLVSFHHRKDIISDIRFSPGSGKYLAVASHDSFVDIYNVT 1113
             + +   L+  L SF   KD I  +++SP +   LA +  D  + +++++
Sbjct: 727  ALWDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLHVWDLS 876

 Score = 31.2 bits (69), Expect = 4.1,   Method: Compositional matrix adjust.
 Identities = 36/165 (21%), Positives = 69/165 (41%), Gaps = 20/165 (12%)
 Frame = +1

Query: 59  GHSDDIISLALHP-ERVLVATGQVGKEPYICVWDSYTVQTVSVLKDVHTHGIACLAFDLD 117
            H+ ++  L+ +P    ++ATG   K   + +WD   ++      + H   I  + +   
Sbjct: 643 AHTAEVNCLSFNPYSEFILATGSADK--TVALWDLRNLKLKLHSFESHKDEIFQVQWSPH 816

Query: 118 GQR-LVSVGLDSKNAVCVWDWKR--------------GRMLSMAPGHTDRIFDISWDLYQ 162
            +  L S G D +  + VWD  +                +L +  GHT +I D SW+  +
Sbjct: 817 NETILASSGTDRR--LHVWDLSKIGEEQLPEDAEDGPPELLFIHGGHTAKISDFSWNPNE 990

Query: 163 PNKLVSCGVKHI-KFWSLCGNALTPKRGVFGKTGDLQ---TILCL 203
           P  + S    +I + W +  N  + +       GDL+   +++CL
Sbjct: 991 PWIVCSVSEDNIMQVWQMAENIYSDEDPDAAGGGDLEAS*SVVCL 1125
>12574
          Length = 521

 Score = 45.4 bits (106), Expect = 2e-04,   Method: Composition-based stats.
 Identities = 33/126 (26%), Positives = 56/126 (44%)
 Frame = +3

Query: 1409 NVATGTQSFYQEHNDDILCLTVNQHPKFINIVATGQVGDSADMSATAPSVHIWDAVNKQT 1468
            +  +GT+S   +     L  T+  H K ++ V     GD    S+    + IW A + + 
Sbjct: 111  SATSGTKSSATQKPTYTLKFTLAGHTKALSAVKFSPNGDWLASSSADKLIKIWGAYDGKF 290

Query: 1469 LSILRCSHSKGVCSVSFSATGKLLLSVGLDPEHTVTIWRWQEGAKIASRGGHNQRIFVAE 1528
               +   H  G+  V++S+  KLL S   D   T+ IW +  G  + +  GH+  +F   
Sbjct: 291  EKTI-AGHKLGLSDVAWSSDSKLLCSASDD--KTLKIWEFSTGKCMKTLKGHSNYVFCCN 461

Query: 1529 FRPDSD 1534
            F P S+
Sbjct: 462  FNPQSN 479

 Score = 41.2 bits (95), Expect = 0.005,   Method: Composition-based stats.
 Identities = 32/119 (26%), Positives = 54/119 (45%), Gaps = 1/119 (0%)
 Frame = +3

Query: 719 TQRFYL-GHDDDILCLAIHPLKDYVATGQVGRDPSIHVWDTETIKPLSILKGYHQYGICA 777
           T +F L GH   +  +   P  D++A+     D  I +W     K    + G H+ G+  
Sbjct: 159 TLKFTLAGHTKALSAVKFSPNGDWLASSSA--DKLIKIWGAYDGKFEKTIAG-HKLGLSD 329

Query: 778 VDFSADGKRLASVGIDDSHTIVLWDWKKGEKLSVTRGSKDKIFVVKMNPYVPDKLITAG 836
           V +S+D K L S    D  T+ +W++  G+ +   +G  + +F    NP     LI +G
Sbjct: 330 VAWSSDSKLLCSA--SDDKTLKIWEFSTGKCMKTLKGHSNYVFCCNFNP--QSNLIVSG 494

 Score = 38.1 bits (87), Expect = 0.040,   Method: Composition-based stats.
 Identities = 16/44 (36%), Positives = 23/44 (52%)
 Frame = +3

Query: 1015 TVSDDKTLRIWDLSPSHCMLAVRKLKKGGRCCCFSPDGKALAVG 1058
            + SDDKTL+IW+ S   CM  ++       CC F+P    +  G
Sbjct: 363  SASDDKTLKIWEFSTGKCMKTLKGHSNYVFCCNFNPQSNLIVSG 494

 Score = 31.6 bits (70), Expect = 3.8,   Method: Composition-based stats.
 Identities = 21/74 (28%), Positives = 34/74 (45%)
 Frame = +3

Query: 1085 ISDIRFSPGSGKYLAVASHDSFVDIYNVTSSKRVGVCKGATSYITHIDWDSRGKLLQVNT 1144
            +S ++FSP +G +LA +S D  + I+     K      G    ++ + W S  KLL   +
Sbjct: 195  LSAVKFSP-NGDWLASSSADKLIKIWGAYDGKFEKTIAGHKLGLSDVAWSSDSKLLCSAS 371

Query: 1145 GAKEQLFFEAPRGK 1158
              K    +E   GK
Sbjct: 372  DDKTLKIWEFSTGK 413
>17598
          Length = 875

 Score = 45.1 bits (105), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 26/88 (29%), Positives = 41/88 (46%)
 Frame = +1

Query: 715 RQQNTQRFYLGHDDDILCLAIHPLKDYVATGQVGRDPSIHVWDTETIKPLSILKGYHQYG 774
           ++ NT R ++ H  D L +A  P    +A+G  GRD ++ +W+T      ++    HQ  
Sbjct: 211 KKGNTTRRFISHTRDALAVAFSPDNRQIASG--GRDKALKIWNTVGECKFTVDANSHQDW 384

Query: 775 ICAVDFSADGKRLASVGIDDSHTIVLWD 802
           +  V F  D K    V      TI +WD
Sbjct: 385 VTCVKFHQDAKSPLVVSASMDKTIKVWD 468

 Score = 37.0 bits (84), Expect = 0.082,   Method: Compositional matrix adjust.
 Identities = 21/97 (21%), Positives = 44/97 (45%)
 Frame = +1

Query: 57  FRGHSDDIISLALHPERVLVATGQVGKEPYICVWDSYTVQTVSVLKDVHTHGIACLAFDL 116
           F  H+ D +++A  P+   +A+G  G++  + +W++      +V  + H   + C+ F  
Sbjct: 235 FISHTRDALAVAFSPDNRQIASG--GRDKALKIWNTVGECKFTVDANSHQDWVTCVKFHQ 408

Query: 117 DGQRLVSVGLDSKNAVCVWDWKRGRMLSMAPGHTDRI 153
           D +  + V       + VWD +   +     GH  +I
Sbjct: 409 DAKSPLVVSASMDKTIKVWDNQTMTLKHTFVGHKTQI 519

 Score = 34.7 bits (78), Expect = 0.41,   Method: Compositional matrix adjust.
 Identities = 42/195 (21%), Positives = 81/195 (41%), Gaps = 7/195 (3%)
 Frame = +1

Query: 1608 AHNGPVFAMYTTLRDGLIVTGGKERPSKEGGAVKLWDQELRRCRAFRLETGQVTD---CV 1664
            +H     A+  +  +  I +GG+++      A+K+W+  +  C+ F ++     D   CV
Sbjct: 241  SHTRDALAVAFSPDNRQIASGGRDK------ALKIWN-TVGECK-FTVDANSHQDWVTCV 396

Query: 1665 RSVCRGKGKILVGTRNSEIIEVGE-KNAACNILVNGH---VDGPIWGLATHPSRDFFLSA 1720
            +     K  ++V     + I+V + +         GH   ++     L T+    +  S 
Sbjct: 397  KFHQDAKSPLVVSASMDKTIKVWDNQTMTLKHTFVGHKTQINAIDLALKTY----YLASG 564

Query: 1721 AEDGTVRLWDIADKKMLNKVNLGHAARTVCYSPEGDMVAIGMKNGEFIILLVSSLKIWGK 1780
            ++DG V  W+I +   L K++       V +SP    + +G   G         ++IW  
Sbjct: 565  SKDGIVMTWNIQNGTFLGKIDCDCEVNAVKFSPNKYWLFVGTSEG---------IQIWDL 717

Query: 1781 KRDRRCAIHDIRFSP 1795
               ++  I DIR SP
Sbjct: 718  PNQKK--IKDIRASP 756

 Score = 32.0 bits (71), Expect = 2.7,   Method: Compositional matrix adjust.
 Identities = 38/163 (23%), Positives = 65/163 (39%), Gaps = 2/163 (1%)
 Frame = +1

Query: 972  LVGTKNGEILEVDKSGPITLLVQGHMEGEVWGLATHPYLPICATVSDDKTLRIWDLSPSH 1031
            LV  K+G+  E       TL    H   +V   A   Y+    + S D TLR+WD+   +
Sbjct: 52   LVPRKDGDEDETWGGPRRTLQGHSHFVSDVSLSADSRYV---LSSSWDATLRLWDIKKGN 222

Query: 1032 CMLAVRKLKKGGRCCCFSPDGKALAVGLNDGSFLMANA-DTLEDLVSFHHRKDIISDIRF 1090
                     +      FSPD + +A G  D +  + N     +  V  +  +D ++ ++F
Sbjct: 223  TTRRFISHTRDALAVAFSPDNRQIASGGRDKALKIWNTVGECKFTVDANSHQDWVTCVKF 402

Query: 1091 SPGSGKYLAV-ASHDSFVDIYNVTSSKRVGVCKGATSYITHID 1132
               +   L V AS D  + +++  +        G  + I  ID
Sbjct: 403  HQDAKSPLVVSASMDKTIKVWDNQTMTLKHTFVGHKTQINAID 531
>21105
          Length = 650

 Score = 43.9 bits (102), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 29/110 (26%), Positives = 53/110 (48%), Gaps = 8/110 (7%)
 Frame = +1

Query: 334 HPTKPLAVTGSDDRSVRIWS----LVDHALIARCNMEEPIRCAAVNVDGIHLALGMKDGS 389
           HPT P+ +T  +DR +R +      + HA++A     + +   AV+ +G++L  G  D S
Sbjct: 91  HPTMPITITAHEDRHIRFFDNNTGKLIHAMVAHL---DSVTSLAVDPNGLYLLSGSHDCS 261

Query: 390 FTVLRVRDMTEV----VHIKDRKEAIHELKYSPDGAYLAVGCNDSSVDIY 435
             +  +   T V     H K   E+IH++ + P   Y+A    D+   ++
Sbjct: 262 IRLWNLDSKTCVQEITSHRKKFDESIHDVAFHPQKPYIASAGADALAKVF 411

 Score = 36.6 bits (83), Expect = 0.097,   Method: Compositional matrix adjust.
 Identities = 29/110 (26%), Positives = 50/110 (45%), Gaps = 6/110 (5%)
 Frame = +1

Query: 1007 HPYLPICATVSDDKTLRIWDLSPSHCMLAVRKLKKGGRCCCFSPDGKALAVGLNDGSFLM 1066
            HP +PI  T  +D+ +R +D +    + A+             P+G  L  G +D S  +
Sbjct: 91   HPTMPITITAHEDRHIRFFDNNTGKLIHAMVAHLDSVTSLAVDPNGLYLLSGSHDCSIRL 270

Query: 1067 ANADT---LEDLVSFHHRKDI---ISDIRFSPGSGKYLAVASHDSFVDIY 1110
             N D+   ++++ S  HRK     I D+ F P    Y+A A  D+   ++
Sbjct: 271  WNLDSKTCVQEITS--HRKKFDESIHDVAFHP-QKPYIASAGADALAKVF 411
>15972
          Length = 1069

 Score = 43.1 bits (100), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 21/58 (36%), Positives = 35/58 (60%)
 Frame = +3

Query: 1698 NGHVDGPIWGLATHPSRDFFLSAAEDGTVRLWDIADKKMLNKVNLGHAARTVCYSPEG 1755
            +GH  GP+  LA HPS    L+ ++D T+RLW+  + ++    N+  AA +V ++P G
Sbjct: 228  SGH-KGPVRHLAVHPSGKLTLTVSQDRTLRLWNNMNGRIAFISNMKEAAESVRWAPGG 398

 Score = 38.5 bits (88), Expect = 0.025,   Method: Compositional matrix adjust.
 Identities = 35/144 (24%), Positives = 56/144 (38%), Gaps = 4/144 (2%)
 Frame = +3

Query: 316 PFLIMQGHCEGELWALAVHPTKPLAVTGSDDRSVRIWSLVDHALIARCNMEEPIRCAAVN 375
           P     GH +G +  LAVHP+  L +T S DR++R+W+                     N
Sbjct: 213 PERTFSGH-KGPVRHLAVHPSGKLTLTVSQDRTLRLWN---------------------N 326

Query: 376 VDGIHLALGMKDGSFTVLRVRDMTEVVHIKDRKEAIHELKYSPDGAYLAVGCNDSSVDIY 435
           ++G                      +  I + KEA   ++++P G Y  V    S +D+Y
Sbjct: 327 MNG---------------------RIAFISNMKEAAESVRWAPGGLYYVVAFR-SHLDVY 440

Query: 436 GVAQ----RYKKVGECVGSLSFIT 455
            V      R     + V S+ F+T
Sbjct: 441 SVESKGLLRSIDTSQTVNSVGFVT 512

 Score = 33.5 bits (75), Expect = 0.80,   Method: Compositional matrix adjust.
 Identities = 19/58 (32%), Positives = 29/58 (50%)
 Frame = +3

Query: 995  GHMEGEVWGLATHPYLPICATVSDDKTLRIWDLSPSHCMLAVRKLKKGGRCCCFSPDG 1052
            GH +G V  LA HP   +  TVS D+TLR+W+         +  +K+      ++P G
Sbjct: 231  GH-KGPVRHLAVHPSGKLTLTVSQDRTLRLWNNMNGRIAF-ISNMKEAAESVRWAPGG 398
>17807
          Length = 484

 Score = 42.7 bits (99), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 36/121 (29%), Positives = 54/121 (44%), Gaps = 15/121 (12%)
 Frame = -2

Query: 1711 HPSRD-FFLSAAEDGTVRLWDIADKK--MLNKVN-LGHAARTVCYSPEGDMVAIGMKNGE 1766
            HP  D +FLS + DG +RLW+I DKK  M N+++   +   T  +   G +  +G  +G 
Sbjct: 435  HPKDDRYFLSGSLDGKIRLWNIPDKKVTMWNELSGSSNLITTASFCHNGRLAVVGTYDGR 256

Query: 1767 FIILLVSSLKIWGK--------KRDRRCAIHDIRFSPDSRYLAVGSSENSVDFY---DLT 1815
             I      LK +          +  R   I  I   P    + V S+++ V  Y   DLT
Sbjct: 255  CIFYTTDQLKYYTMLNVRSTRGRNARGRKITGIEAMPGEEKILVTSNDSRVRLYSLKDLT 76

Query: 1816 L 1816
            L
Sbjct: 75   L 73

 Score = 35.4 bits (80), Expect = 0.23,   Method: Compositional matrix adjust.
 Identities = 28/119 (23%), Positives = 49/119 (41%), Gaps = 6/119 (5%)
 Frame = -2

Query: 250 FATGGRDGCIRLWDLTFKPITVIDLRETEQGYKGLSVRSVCWRGDHILVGTQDSEIFEIV 309
           F +G  DG IRLW++  K +T+ +  E       ++  S C  G   +VGT D       
Sbjct: 414 FLSGSLDGKIRLWNIPDKKVTMWN--ELSGSSNLITTASFCHNGRLAVVGTYDGRCIFYT 241

Query: 310 VHERNKPFLIMQGHCEG------ELWALAVHPTKPLAVTGSDDRSVRIWSLVDHALIAR 362
             +     ++      G      ++  +   P +   +  S+D  VR++SL D  L  +
Sbjct: 240 TDQLKYYTMLNVRSTRGRNARGRKITGIEAMPGEEKILVTSNDSRVRLYSLKDLTLTCK 64
>12806
          Length = 961

 Score = 40.4 bits (93), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 22/97 (22%), Positives = 46/97 (47%)
 Frame = +3

Query: 57  FRGHSDDIISLALHPERVLVATGQVGKEPYICVWDSYTVQTVSVLKDVHTHGIACLAFDL 116
           F  H+ D++++A  P+   +A+G  G++  + +W+       +V  + HT  + C+ F  
Sbjct: 279 FINHTRDVLTVAFSPDNRQIASG--GRDKNLKIWNIMGECKYTVDANAHTDWVTCVRFHQ 452

Query: 117 DGQRLVSVGLDSKNAVCVWDWKRGRMLSMAPGHTDRI 153
           D +  + V   +   + VWD     + +   GH  +I
Sbjct: 453 DTKNPIVVSASNDKTIKVWDNHTMTLKNTFVGHKAQI 563

 Score = 36.6 bits (83), Expect = 0.12,   Method: Compositional matrix adjust.
 Identities = 40/194 (20%), Positives = 85/194 (43%), Gaps = 7/194 (3%)
 Frame = +3

Query: 1609 HNGPVFAMYTTLRDGLIVTGGKERPSKEGGAVKLWDQELRRCRAFRLETGQVTD---CVR 1665
            H   V  +  +  +  I +GG+++       +K+W+  +  C+ + ++    TD   CVR
Sbjct: 288  HTRDVLTVAFSPDNRQIASGGRDKN------LKIWNI-MGECK-YTVDANAHTDWVTCVR 443

Query: 1666 SVCRGKGKILVGTRNSEIIEVGEKNAACNILVNGHVDGPIWGLATHPSRDFFLSAAEDGT 1725
                 K  I+V   N + I+V + +     L N  V       A   S ++ +S ++DG 
Sbjct: 444  FHQDTKNPIVVSASNDKTIKVWDNHTMT--LKNTFVGHKAQITALDMSTNYLVSGSKDGI 617

Query: 1726 VRLWDIADKKMLNKVNLGHAARTVCYSPEGDM----VAIGMKNGEFIILLVSSLKIWGKK 1781
               W++A+   + K++       + ++ E +     + IG +NG         ++IW   
Sbjct: 618  AMTWNVAEGSFVGKIDCDDQINAIKFNIENNKKKVWLFIGTQNG---------IQIWDYS 770

Query: 1782 RDRRCAIHDIRFSP 1795
             +++  I +++ SP
Sbjct: 771  GEKK--IKELKASP 806

 Score = 34.7 bits (78), Expect = 0.41,   Method: Compositional matrix adjust.
 Identities = 49/207 (23%), Positives = 79/207 (38%), Gaps = 16/207 (7%)
 Frame = +3

Query: 739 KDYVATGQVGRDPSIHVWDTETIK----------PLSILKGYHQYGICAVDFSADGKRLA 788
           K ++ +G  GRD +I VWD    K          P   L G H + I  +  SAD +   
Sbjct: 45  KPFLISG--GRDNNIIVWDL*PKKDGDEDQTWGVPRKTLTG-HSHFISDLALSADSRFAL 215

Query: 789 SVGIDDSHTIVLWDWKKGEKLSVTRGSKDKIFVVKMNPYVPDKLITAG--IKHMKFWRRA 846
           S   D   T+ LWD KKG   S        +  V  +P   ++ I +G   K++K W   
Sbjct: 216 SSSWD--ATLRLWDIKKGSTTSRFINHTRDVLTVAFSP--DNRQIASGGRDKNLKIWNIM 383

Query: 847 XXXXXXXXXXXXTLGKNDTMMCAVY--GWTEEMAFSGTSTGDVCIWRD--VFLVKTVKAH 902
                       T    D + C  +       +  S ++   + +W +  + L  T   H
Sbjct: 384 GECKYTVDANAHT----DWVTCVRFHQDTKNPIVVSASNDKTIKVWDNHTMTLKNTFVGH 551

Query: 903 DGPVFSMHALEKGFVTGGKDGMVALWD 929
              + ++       V+G KDG+   W+
Sbjct: 552 KAQITALDMSTNYLVSGSKDGIAMTWN 632

 Score = 31.2 bits (69), Expect = 4.8,   Method: Compositional matrix adjust.
 Identities = 34/161 (21%), Positives = 63/161 (39%)
 Frame = +3

Query: 307 EIVVHERNKPFLIMQGHCEGELWALAVHPTKPLAVTGSDDRSVRIWSLVDHALIARCNME 366
           E VV    KPFLI  G  +  +    + P K     G +D++   W +    L    +  
Sbjct: 21  EQVVDGATKPFLISGGR-DNNIIVWDL*PKKD----GDEDQT---WGVPRKTLTGHSHF- 173

Query: 367 EPIRCAAVNVDGIHLALGMKDGSFTVLRVRDMTEVVHIKDRKEAIHELKYSPDGAYLAVG 426
             I   A++ D         D +  +  ++  +      +    +  + +SPD   +A G
Sbjct: 174 --ISDLALSADSRFALSSSWDATLRLWDIKKGSTTSRFINHTRDVLTVAFSPDNRQIASG 347

Query: 427 CNDSSVDIYGVAQRYKKVGECVGSLSFITHLDWSSDSRYLQ 467
             D ++ I+ +      +GEC  ++    H DW +  R+ Q
Sbjct: 348 GRDKNLKIWNI------MGECKYTVDANAHTDWVTCVRFHQ 452
>01598
          Length = 1545

 Score = 40.0 bits (92), Expect = 0.009,   Method: Compositional matrix adjust.
 Identities = 90/409 (22%), Positives = 150/409 (36%), Gaps = 44/409 (10%)
 Frame = +1

Query: 1607 RAHNGPVFAMYTTLRDG-LIVTGGKERPSKEGGAVKLWDQELRRCRAFRLETGQVTDCVR 1665
            R H  PVF +  +  D   + T  ++R       V LWD E     A     G    CVR
Sbjct: 367  RPHMRPVFNICASGPDSKTLCTFAQDR------QVVLWDLETMEAVASMATLGGHVYCVR 528

Query: 1666 SVCRGKGKILVGTRNSEIIEVGEKNAA----CNILVNGHVDGPIWGLATHPSRDFFLS-A 1720
            +     G++ VG  +S I      N         L  G +   +  +A HP+++ +L   
Sbjct: 529  TSPIDPGRVAVGVGDSMIRTWNMSNKTNPYDVTTLWQG-IKSKVTAVAWHPTKEGWLGFG 705

Query: 1721 AEDGTVRLWDIADKKMLNKVNLGH--AARTVCYSPEGDMVAIGMKNGEFII----LLVSS 1774
             +DG + ++D+   KM    N  H   A  VC+ P       G     + +    +L  S
Sbjct: 706  TDDGRIGVFDVLSHKMPTLSNTFHHRTAYVVCWGPASLSPTDGKSFSLYSVGDCKILEHS 885

Query: 1775 LKIWGKKRDRRCAIH-------------------DIRFSPDSRYLAVGSSENS---VDFY 1812
              +  +   +  AI                    ++ +SPD    AVG+ E S   V   
Sbjct: 886  SAVLSRGEKKANAIDITQKIGAVNSDQVKGLKATELSWSPDQNAAAVGTDEGSVYVVTIQ 1065

Query: 1813 DLTLGPTLNR----ISYCKDIPSFVIQMDFSADSRHLQVSSGCYKRHVYEVPSGKHLVDH 1868
            DL +   +      I+  +  P    Q    +   H   ++G  +          H+VD 
Sbjct: 1066 DLKIVAAIRTQQKLINCVRWHPRLTDQSPAGSPCCHWLAAAGNDQV--------IHVVDL 1221

Query: 1869 AAI------DRITWATWTSILGDEVMGIWSRHAEKADVTCACVSHSGISLVTGDDFGMVK 1922
            A++      D+ T    TS+   E+ G    H+++         H    +  G D     
Sbjct: 1222 ASVFAEREGDKETSLILTSL--RELSG----HSQRVTDMSWSPHHDARLVSVGYD-AEAF 1380

Query: 1923 LYDFPCPEKFAKHKRFLGHSPHVTNIRFTSGDRHVVSAGGDDCSLFVWK 1971
            ++D    +K     +F GH   +   +F+  D  +V  GG D S+ VW+
Sbjct: 1381 VWDV---QKGTALAQFKGHMGRLLTCQFSGLDPDLVMTGGSDASVHVWR 1518

 Score = 33.5 bits (75), Expect = 0.90,   Method: Compositional matrix adjust.
 Identities = 23/80 (28%), Positives = 38/80 (47%), Gaps = 3/80 (3%)
 Frame = +1

Query: 148  GHTDRIFDISWDLYQPNKLVSCGVKHIKF-WSLC-GNALTPKRGVFGKTGDLQTILCLAC 205
            GH+ R+ D+SW  +   +LVS G     F W +  G AL   +G  G+      + C   
Sbjct: 1294 GHSQRVTDMSWSPHHDARLVSVGYDAEAFVWDVQKGTALAQFKGHMGR-----LLTCQFS 1458

Query: 206  ARD-ELTYSGALNGDIYVWK 224
              D +L  +G  +  ++VW+
Sbjct: 1459 GLDPDLVMTGGSDASVHVWR 1518

 Score = 31.6 bits (70), Expect = 3.7,   Method: Compositional matrix adjust.
 Identities = 17/51 (33%), Positives = 28/51 (54%)
 Frame = +1

Query: 120  RLVSVGLDSKNAVCVWDWKRGRMLSMAPGHTDRIFDISWDLYQPNKLVSCG 170
            RLVSVG D++    VWD ++G  L+   GH  R+    +    P+ +++ G
Sbjct: 1345 RLVSVGYDAE--AFVWDVQKGTALAQFKGHMGRLLTCQFSGLDPDLVMTGG 1491

 Score = 31.2 bits (69), Expect = 4.1,   Method: Compositional matrix adjust.
 Identities = 20/77 (25%), Positives = 39/77 (50%), Gaps = 10/77 (12%)
 Frame = +1

Query: 1048 FSPDGKALAVGLNDGSFLMANADTLEDLVSFHHRKDIISDIRFSP--------GSG--KY 1097
            +SPD  A AVG ++GS  +     L+ + +   ++ +I+ +R+ P        GS    +
Sbjct: 997  WSPDQNAAAVGTDEGSVYVVTIQDLKIVAAIRTQQKLINCVRWHPRLTDQSPAGSPCCHW 1176

Query: 1098 LAVASHDSFVDIYNVTS 1114
            LA A +D  + + ++ S
Sbjct: 1177 LAAAGNDQVIHVVDLAS 1227
>29912
          Length = 510

 Score = 39.7 bits (91), Expect = 0.012,   Method: Compositional matrix adjust.
 Identities = 28/106 (26%), Positives = 45/106 (42%), Gaps = 13/106 (12%)
 Frame = +3

Query: 1715 DFFLSAAEDGTVRLWDIADKKMLNKVNLGHAARTVCYSPEGDMVAIGMKNGEFIILLVSS 1774
            ++       G V++WD+  +K L +   GHAAR    S    +V+ G ++G         
Sbjct: 48   NYLALGTSTGEVQVWDVTQQKKL-RTMAGHAARVGSLSWNSFIVSSGSRSGNI------- 203

Query: 1775 LKIWGKKRDRRCAIHDI-------------RFSPDSRYLAVGSSEN 1807
                    D R A H +             R+SPD +YLA G+++N
Sbjct: 204  -----HHHDVRVADHHVGTLSGHSQEVCGLRWSPDGKYLASGANDN 326

 Score = 31.6 bits (70), Expect = 3.1,   Method: Compositional matrix adjust.
 Identities = 22/95 (23%), Positives = 45/95 (47%), Gaps = 2/95 (2%)
 Frame = +3

Query: 343 GSDDRSVRIWSLVDHALIARCNMEEPIRCAAVNVDGIHLALGMKDGSFTV--LRVRDMTE 400
           G+    V++W +     + R       R  +++ +   ++ G + G+     +RV D   
Sbjct: 63  GTSTGEVQVWDVTQQKKL-RTMAGHAARVGSLSWNSFIVSSGSRSGNIHHHDVRVADH-H 236

Query: 401 VVHIKDRKEAIHELKYSPDGAYLAVGCNDSSVDIY 435
           V  +    + +  L++SPDG YLA G ND+ + ++
Sbjct: 237 VGTLSGHSQEVCGLRWSPDGKYLASGANDNLLCVW 341
>16199
          Length = 694

 Score = 39.7 bits (91), Expect = 0.013,   Method: Composition-based stats.
 Identities = 24/104 (23%), Positives = 47/104 (45%), Gaps = 5/104 (4%)
 Frame = +1

Query: 1716 FFLSAAEDGTVRLWDIADKKMLNKVNLG--HAARTVCYSPEGDMVAIGMKNGEFIILLVS 1773
            +  ++AED  V+LWD+   K    + LG  +  + +C+   G  +A+   +     + V 
Sbjct: 238  YLATSAEDSVVKLWDLRKLKNFKTLQLGDKYEVKALCFDQSGTYLAVAGSD-----VRVY 402

Query: 1774 SLKIWGKK---RDRRCAIHDIRFSPDSRYLAVGSSENSVDFYDL 1814
              K W +     D       +RF  ++ ++A  S + S+ F+ L
Sbjct: 403  LCKQWNELAVFNDHTATATGVRFGTNANFIASASMDRSLKFFGL 534
>37180
          Length = 681

 Score = 39.3 bits (90), Expect = 0.015,   Method: Compositional matrix adjust.
 Identities = 26/82 (31%), Positives = 41/82 (50%), Gaps = 2/82 (2%)
 Frame = +1

Query: 319 IMQGHCEGELWALAVHPTKPLAVTGSDDRSVRIWSLVDHALIARC--NMEEPIRCAAVNV 376
           ++ GH + EL  +  HPT+ L VT S D + R+W   D AL+        +P+  +AV  
Sbjct: 4   VLNGH-DQELSDVHAHPTQRLVVTSSKDMTFRLWDFRDSALLVNVFQGHTQPV-TSAVFA 177

Query: 377 DGIHLALGMKDGSFTVLRVRDM 398
            G  +  G  D +  V  +R+M
Sbjct: 178 SGDKVVSGSDDRTVRVWDMRNM 243

 Score = 38.9 bits (89), Expect = 0.021,   Method: Compositional matrix adjust.
 Identities = 28/98 (28%), Positives = 46/98 (46%), Gaps = 1/98 (1%)
 Frame = +1

Query: 1696 LVNGHVDGPIWGLATHPSRDFFLSAAEDGTVRLWDIADKKMLNKVNLGHAAR-TVCYSPE 1754
            ++NGH D  +  +  HP++   +++++D T RLWD  D  +L  V  GH    T      
Sbjct: 4    VLNGH-DQELSDVHAHPTQRLVVTSSKDMTFRLWDFRDSALLVNVFQGHTQPVTSAVFAS 180

Query: 1755 GDMVAIGMKNGEFIILLVSSLKIWGKKRDRRCAIHDIR 1792
            GD V  G  +         ++++W   R+ R  I  IR
Sbjct: 181  GDKVVSGSDD--------RTVRVW-DMRNMRSPIATIR 267
>13278
          Length = 870

 Score = 38.5 bits (88), Expect = 0.026,   Method: Compositional matrix adjust.
 Identities = 21/60 (35%), Positives = 31/60 (51%)
 Frame = +1

Query: 1012 ICATVSDDKTLRIWDLSPSHCMLAVRKLKKGGRCCCFSPDGKALAVGLNDGSFLMANADT 1071
            I A+ S D T+R+W++    C+  + K ++      FSPDGK LA G  D    + N  T
Sbjct: 118  ILASASFDSTVRLWEVERGLCLHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNVQT 297

 Score = 32.7 bits (73), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 14/67 (20%), Positives = 29/67 (43%)
 Frame = +1

Query: 1704 PIWGLATHPSRDFFLSAAEDGTVRLWDIADKKMLNKVNLGHAARTVCYSPEGDMVAIGMK 1763
            P++ +A  P   +  S + D  V +W++    +++          VC++  GD V     
Sbjct: 208  PVYSVAFSPDGKYLASGSFDKCVHIWNVQTGSLVHSYKGTGGIFEVCWNHRGDKVGASAS 387

Query: 1764 NGEFIIL 1770
            +G   +L
Sbjct: 388  DGSVFVL 408

 Score = 32.0 bits (71), Expect = 2.3,   Method: Compositional matrix adjust.
 Identities = 13/34 (38%), Positives = 20/34 (58%)
 Frame = +1

Query: 404 IKDRKEAIHELKYSPDGAYLAVGCNDSSVDIYGV 437
           +   +E ++ + +SPDG YLA G  D  V I+ V
Sbjct: 190 LTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNV 291

 Score = 31.2 bits (69), Expect = 4.8,   Method: Compositional matrix adjust.
 Identities = 23/104 (22%), Positives = 46/104 (44%), Gaps = 14/104 (13%)
 Frame = +1

Query: 1728 LWDIADKKMLNKVNLG-HAARTVCYSPEGDMVAIGMKNGEFIILLVS-----SLKIWGKK 1781
            +W +     ++ + L      T+ +SP G     G  N    ++L S     ++++W  +
Sbjct: 1    IWSMGKDSCIHDLQLTTKEIYTIKWSPTGP----GTSNPNTSLILASASFDSTVRLWEVE 168

Query: 1782 R--------DRRCAIHDIRFSPDSRYLAVGSSENSVDFYDLTLG 1817
            R          +  ++ + FSPD +YLA GS +  V  +++  G
Sbjct: 169  RGLCLHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNVQTG 300
>34005
          Length = 456

 Score = 37.7 bits (86), Expect = 0.051,   Method: Compositional matrix adjust.
 Identities = 22/69 (31%), Positives = 37/69 (53%), Gaps = 3/69 (4%)
 Frame = +1

Query: 1791 IRFSPDSRYLAVGSSENSVDFYDLTLG---PTLNRISYCKDIPSFVIQMDFSADSRHLQV 1847
            + +SPD+ +LA GS++NSV+ +D TLG   P L+ ++  +     V    +   +R L  
Sbjct: 130  LSWSPDATFLASGSNDNSVNIWDSTLGMDVPPLHTLTSHQAAVKAVAWCPW--QTRMLAT 303

Query: 1848 SSGCYKRHV 1856
              G   RH+
Sbjct: 304  GGGTNDRHI 330
>21921
          Length = 1341

 Score = 37.4 bits (85), Expect = 0.069,   Method: Compositional matrix adjust.
 Identities = 15/81 (18%), Positives = 40/81 (49%)
 Frame = -1

Query: 1695 ILVNGHVDGPIWGLATHPSRDFFLSAAEDGTVRLWDIADKKMLNKVNLGHAARTVCYSPE 1754
            ++  GH  G +  +   P+  + +S ++DGT+R W+++  + +  + +G    +V ++P 
Sbjct: 501  LVYKGHT-GIVRSICPDPTGQWLVSGSDDGTIRFWEVSSGRCMKTLQVGGCVTSVAWNPN 325

Query: 1755 GDMVAIGMKNGEFIILLVSSL 1775
              +  +       ++L+   L
Sbjct: 324  PSLCVVAATLNTTVLLINPGL 262
>00561
          Length = 1003

 Score = 37.0 bits (84), Expect = 0.072,   Method: Compositional matrix adjust.
 Identities = 21/93 (22%), Positives = 43/93 (46%)
 Frame = -3

Query: 57  FRGHSDDIISLALHPERVLVATGQVGKEPYICVWDSYTVQTVSVLKDVHTHGIACLAFDL 116
           F GH+ D++S+A   +   + +G   K   I +W++      ++ +D HT  ++C+ F  
Sbjct: 752 FEGHTKDVLSVAFSADNRQIVSGSRDKT--IKLWNTLAECKFTIQEDGHTDWVSCVRFSP 579

Query: 117 DGQRLVSVGLDSKNAVCVWDWKRGRMLSMAPGH 149
           +    + V       V VW+    ++ +   GH
Sbjct: 578 NHSNPIIVSCGWDRTVKVWNLANCKLKNNHHGH 480

 Score = 36.6 bits (83), Expect = 0.093,   Method: Compositional matrix adjust.
 Identities = 35/151 (23%), Positives = 58/151 (38%), Gaps = 3/151 (1%)
 Frame = -3

Query: 1607 RAHNGPVFAMYTTLRDGLIVTGGKERPSKEGGAVKLWDQELRRCRAFRLETGQV--TDCV 1664
              H   V ++  +  +  IV+G +++       +KLW+  L  C+    E G      CV
Sbjct: 749  EGHTKDVLSVAFSADNRQIVSGSRDK------TIKLWNT-LAECKFTIQEDGHTDWVSCV 591

Query: 1665 RSVCRGKGKILVGTRNSEIIEVGEKNAACNILVNGHV-DGPIWGLATHPSRDFFLSAAED 1723
            R        I+V       ++V    A C +  N H  +G +  +   P      S  +D
Sbjct: 590  RFSPNHSNPIIVSCGWDRTVKVWNL-ANCKLKNNHHGHNGYLNTVTVSPDGSLCTSGGKD 414

Query: 1724 GTVRLWDIADKKMLNKVNLGHAARTVCYSPE 1754
                LWD+ D K L  +        +C+SP 
Sbjct: 413  SKALLWDLNDGKNLYTLEHNDIINALCFSPN 321

 Score = 36.2 bits (82), Expect = 0.12,   Method: Compositional matrix adjust.
 Identities = 34/145 (23%), Positives = 55/145 (37%), Gaps = 4/145 (2%)
 Frame = -3

Query: 1019 DKTLRIWDLSPSHCMLAVRKLKKGGRCCCFSPDGKALAVGLNDGSFLMANADTLEDL--- 1075
            D+TLR+WDL+            K      FS D + +  G  D +  + N  TL +    
Sbjct: 803  DQTLRLWDLAAGKTTRRFEGHTKDVLSVAFSADNRQIVSGSRDKTIKLWN--TLAECKFT 630

Query: 1076 VSFHHRKDIISDIRFSPG-SGKYLAVASHDSFVDIYNVTSSKRVGVCKGATSYITHIDWD 1134
            +      D +S +RFSP  S   +     D  V ++N+ + K      G   Y+  +   
Sbjct: 629  IQEDGHTDWVSCVRFSPNHSNPIIVSCGWDRTVKVWNLANCKLKNNHHGHNGYLNTVTVS 450

Query: 1135 SRGKLLQVNTGAKEQLFFEAPRGKR 1159
              G L        + L ++   GK 
Sbjct: 449  PDGSLCTSGGKDSKALLWDLNDGKN 375

 Score = 32.0 bits (71), Expect = 2.4,   Method: Compositional matrix adjust.
 Identities = 30/118 (25%), Positives = 50/118 (42%), Gaps = 12/118 (10%)
 Frame = -3

Query: 1011 PICATVSDDKTLRIWDLSPSHCML------------AVRKLKKGGRCCCFSPDGKALAVG 1058
            PI  +   D+T+++W+L+  +C L             V     G  C     D KAL   
Sbjct: 566  PIIVSCGWDRTVKVWNLA--NCKLKNNHHGHNGYLNTVTVSPDGSLCTSGGKDSKALLWD 393

Query: 1059 LNDGSFLMANADTLEDLVSFHHRKDIISDIRFSPGSGKYLAVASHDSFVDIYNVTSSK 1116
            LNDG          ++L +  H  DII+ + FSP   +Y    ++   + I+++   K
Sbjct: 392  LNDG----------KNLYTLEH-NDIINALCFSP--NRYWLCVAYGPSIKIWDLACKK 258

 Score = 30.4 bits (67), Expect = 7.8,   Method: Compositional matrix adjust.
 Identities = 24/85 (28%), Positives = 35/85 (41%)
 Frame = -3

Query: 725 GHDDDILCLAIHPLKDYVATGQVGRDPSIHVWDTETIKPLSILKGYHQYGICAVDFSADG 784
           GH D + C+   P          G D ++ VW+    K  +   G++ Y +  V  S DG
Sbjct: 617 GHTDWVSCVRFSPNHSNPIIVSCGWDRTVKVWNLANCKLKNNHHGHNGY-LNTVTVSPDG 441

Query: 785 KRLASVGIDDSHTIVLWDWKKGEKL 809
               S G D     +LWD   G+ L
Sbjct: 440 SLCTSGGKDSK--ALLWDLNDGKNL 372
>21960
          Length = 756

 Score = 37.0 bits (84), Expect = 0.076,   Method: Compositional matrix adjust.
 Identities = 21/60 (35%), Positives = 32/60 (53%), Gaps = 1/60 (1%)
 Frame = +1

Query: 970  HILVGTKNGEILEVDK-SGPITLLVQGHMEGEVWGLATHPYLPICATVSDDKTLRIWDLS 1028
            HI+ G+ +G I   DK +  +T  ++G   G V  L  HP +P+ AT   D  ++IW  S
Sbjct: 406  HIISGSDDGNIFYWDKNTEAVTNFMKGDDAGVVNCLEQHPTMPVLATSGLDHNVKIWTPS 585

 Score = 32.7 bits (73), Expect = 1.4,   Method: Compositional matrix adjust.
 Identities = 20/62 (32%), Positives = 32/62 (51%), Gaps = 2/62 (3%)
 Frame = +1

Query: 294 DHILVGTQDSEIFEIVVHERNKPFL--IMQGHCEGELWALAVHPTKPLAVTGSDDRSVRI 351
           +HI+ G+ D  IF     ++N   +   M+G   G +  L  HPT P+  T   D +V+I
Sbjct: 403 EHIISGSDDGNIF---YWDKNTEAVTNFMKGDDAGVVNCLEQHPTMPVLATSGLDHNVKI 573

Query: 352 WS 353
           W+
Sbjct: 574 WT 579
>03395
          Length = 2795

 Score = 37.0 bits (84), Expect = 0.085,   Method: Compositional matrix adjust.
 Identities = 51/255 (20%), Positives = 93/255 (36%)
 Frame = +2

Query: 1717 FLSAAEDGTVRLWDIADKKMLNKVNLGHAARTVCYSPEGDMVAIGMKNGEFIILLVSSLK 1776
             +S   +G VR+WDI    +  K               GD+VA                 
Sbjct: 41   LVSGGGEGQVRVWDIVKDMLTGK-------------TRGDLVA----------------- 130

Query: 1777 IWGKKRDRRCAIHDIRFSPDSRYLAVGSSENSVDFYDLTLGPTLNRISYCKDIPSFVIQM 1836
                 ++ +  +  I+   + R     S++ S   +DL +  T ++I     +   V   
Sbjct: 131  ---NMKEHKGKVTAIQIHTNDRCCVSASTDGSTIIWDL-ITNTRSQIVLANTLFKCVC-- 292

Query: 1837 DFSADSRHLQVSSGCYKRHVYEVPSGKHLVDHAAIDRITWATWTSILGDEVMGIWSRHAE 1896
             F     H+  S   +K   +EV  G  L                    E+ G     ++
Sbjct: 293  -FGGKDLHILTSGTDHKIGYWEVGDGGLL-------------------RELEG-----SQ 397

Query: 1897 KADVTCACVSHSGISLVTGDDFGMVKLYDFPCPEKFAKHKRFLGHSPHVTNIRFTSGDRH 1956
               +    +   G +++TG +  ++KL+ +   E    H   +GHS  +T  R    +RH
Sbjct: 398  TGAINTIDIDRDGQTILTGGEDSLLKLWRYN--EGEVTHT-GIGHSNQITKARICP-NRH 565

Query: 1957 VVSAGGDDCSLFVWK 1971
             + +GG+D +L +WK
Sbjct: 566  YIVSGGEDGALHIWK 610

 Score = 30.8 bits (68), Expect = 6.1,   Method: Compositional matrix adjust.
 Identities = 19/81 (23%), Positives = 36/81 (44%)
 Frame = +2

Query: 1452 SATAPSVHIWDAVNKQTLSILRCSHSKGVCSVSFSATGKLLLSVGLDPEHTVTIWRWQEG 1511
            S T   +  W+  +   L  L  S +  + ++     G+ +L+ G D    + +WR+ EG
Sbjct: 323  SGTDHKIGYWEVGDGGLLRELEGSQTGAINTIDIDRDGQTILTGGEDS--LLKLWRYNEG 496

Query: 1512 AKIASRGGHNQRIFVAEFRPD 1532
                +  GH+ +I  A   P+
Sbjct: 497  EVTHTGIGHSNQITKARICPN 559
>17602
          Length = 481

 Score = 37.0 bits (84), Expect = 0.087,   Method: Compositional matrix adjust.
 Identities = 23/103 (22%), Positives = 50/103 (48%), Gaps = 1/103 (0%)
 Frame = +3

Query: 55  KFFRGHSDDIISLALHPERVLVATGQVGKEPYIC-VWDSYTVQTVSVLKDVHTHGIACLA 113
           K    HSD + ++  + +  L+ +        +C +WD+ + Q +  L D     ++ + 
Sbjct: 36  KTLPAHSDPVTAVHFNRDGSLIVSSSYDG---LCRIWDTASGQCLXTLIDDDNPPVSFVK 206

Query: 114 FDLDGQRLVSVGLDSKNAVCVWDWKRGRMLSMAPGHTDRIFDI 156
           F  +G+ +++  LD  N + +WD+ +G+ L    GH +  + I
Sbjct: 207 FSPNGKYILAATLD--NTLKLWDYSKGKCLKTYVGHRNEKYCI 329

 Score = 36.2 bits (82), Expect = 0.13,   Method: Compositional matrix adjust.
 Identities = 24/92 (26%), Positives = 43/92 (46%)
 Frame = +3

Query: 734 AIHPLKDYVATGQVGRDPSIHVWDTETIKPLSILKGYHQYGICAVDFSADGKRLASVGID 793
           A+H  +D         D    +WDT + + L  L       +  V FS +GK + +  +D
Sbjct: 69  AVHFNRDGSLIVSSSYDGLCRIWDTASGQCLXTLIDDDNPPVSFVKFSPNGKYILAATLD 248

Query: 794 DSHTIVLWDWKKGEKLSVTRGSKDKIFVVKMN 825
           +  T+ LWD+ KG+ L    G +++ + +  N
Sbjct: 249 N--TLKLWDYSKGKCLKTYVGHRNEKYCIFAN 338

 Score = 33.5 bits (75), Expect = 0.98,   Method: Compositional matrix adjust.
 Identities = 23/89 (25%), Positives = 39/89 (43%), Gaps = 4/89 (4%)
 Frame = +3

Query: 896 VKTVKAHDGPVFSMHALEKG--FVTGGKDGMVALWDDSFERCLKTYAIKRADLAPGSKGL 953
           +KT+ AH  PV ++H    G   V+   DG+  +WD +  +CL T              L
Sbjct: 33  LKTLPAHSDPVTAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLXT--------------L 170

Query: 954 LLEDNPSIRAISLGHG--HILVGTKNGEI 980
           + +DNP +  +       +IL  T +  +
Sbjct: 171 IDDDNPPVSFVKFSPNGKYILAATLDNTL 257
>18981
          Length = 407

 Score = 36.6 bits (83), Expect = 0.10,   Method: Compositional matrix adjust.
 Identities = 32/105 (30%), Positives = 53/105 (50%), Gaps = 1/105 (0%)
 Frame = -2

Query: 725 GHDDDILCLAIHPLKDYVATGQVGRDPSIHVWDTETIKPLSILKGYHQYGICAVDFSADG 784
           GH+DD+ C+ I+  +  V +G    D ++ VW+ +T +P+  L G H   I AV F  +G
Sbjct: 304 GHNDDVECVCIYGRR--VVSGS--WDKTLIVWEVDTGRPVHQLHG-HTEAITAVQFD-EG 143

Query: 785 KRLASVGIDDSHTIVLWDWKKGE-KLSVTRGSKDKIFVVKMNPYV 828
           K ++     D  T   W    G+  L++T G   +++ V  N  V
Sbjct: 142 KAVSGSADGDVRT---WALDTGQCLLTMTTGQDIEVYCVVYNQEV 17

 Score = 30.8 bits (68), Expect = 5.1,   Method: Compositional matrix adjust.
 Identities = 18/79 (22%), Positives = 35/79 (44%)
 Frame = -2

Query: 1015 TVSDDKTLRIWDLSPSHCMLAVRKLKKGGRCCCFSPDGKALAVGLNDGSFLMANADTLED 1074
            + + D+TLR+W L  +  +  +R       C C    G+ +  G  D + ++   DT   
Sbjct: 373  SAATDRTLRVWCLKNTCLLHTLRGHNDDVECVCIY--GRRVVSGSWDKTLIVWEVDTGRP 200

Query: 1075 LVSFHHRKDIISDIRFSPG 1093
            +   H   + I+ ++F  G
Sbjct: 199  VHQLHGHTEAITAVQFDEG 143
>20662
          Length = 1220

 Score = 36.6 bits (83), Expect = 0.11,   Method: Compositional matrix adjust.
 Identities = 21/70 (30%), Positives = 35/70 (50%), Gaps = 5/70 (7%)
 Frame = +2

Query: 1705 IWGLATHPSRD-FFLSAAEDGTVRLWDIADKK---MLNKVNLGHAARTVCYSPEG-DMVA 1759
            +W +  HP+    FLS ++DG + LWD+ + K    L K + G     V + P   +M A
Sbjct: 518  VWDVQCHPTEPALFLSCSQDGKIVLWDVRESKPATCLPKCSSGFKPTCVQWQPNARNMYA 697

Query: 1760 IGMKNGEFII 1769
            +G + G   +
Sbjct: 698  VGDEGGHVSV 727
>35695
          Length = 1651

 Score = 36.6 bits (83), Expect = 0.11,   Method: Compositional matrix adjust.
 Identities = 18/58 (31%), Positives = 29/58 (50%)
 Frame = -3

Query: 1725 TVRLWDIADKKMLNKVNLGHAARTVCYSPEGDMVAIGMKNGEFIILLVSSLKIWGKKR 1782
            T+RL+ ++D KML     G   R++  SP G  V +G  +G    L ++  +    KR
Sbjct: 608  TIRLFRVSDGKMLANYKAGAEVRSIVCSPAGTAVVLGAVDGSLTTLAIADPEDEDHKR 435
>15118
          Length = 1074

 Score = 36.2 bits (82), Expect = 0.14,   Method: Compositional matrix adjust.
 Identities = 32/127 (25%), Positives = 56/127 (44%), Gaps = 3/127 (2%)
 Frame = +3

Query: 995  GHMEGEVWGLATHPYLPICATVSDDKTLRIWDLSP---SHCMLAVRKLKKGGRCCCFSPD 1051
             H+ G V G+A   +  +  T   D  ++ W       +  +L   K+ +G        D
Sbjct: 186  AHVSG-VRGVAFDAFNCLLITAGGDCDIKFWRFGSRDRARVLLKELKMSEGISRILLHRD 362

Query: 1052 GKALAVGLNDGSFLMANADTLEDLVSFHHRKDIISDIRFSPGSGKYLAVASHDSFVDIYN 1111
               LAV L D +  + + DTL  +  F    + I+D+ FS G G++L  AS D  V  ++
Sbjct: 363  SNMLAVVLEDFTVSVIDVDTLRVVRVFSGHSNSITDLSFS-GDGRWLITASMDCTVRTWS 539

Query: 1112 VTSSKRV 1118
            +   + +
Sbjct: 540  LVHGRLI 560
>10264
          Length = 416

 Score = 35.0 bits (79), Expect = 0.31,   Method: Compositional matrix adjust.
 Identities = 23/80 (28%), Positives = 38/80 (47%), Gaps = 3/80 (3%)
 Frame = -1

Query: 148 GHTDRIFDISWDLYQPNKLVSCGVKHIKF-WSLC-GNALTPKRGVFGKTGDLQTILCLAC 205
           GH+ R+ D+SW  +   +LVS G     F W +  G AL   +G  G+      + C   
Sbjct: 251 GHSQRVTDMSWSPHHDARLVSVGYDAEAFVWDVQKGTALAQFKGHMGR-----LLTCQFS 87

Query: 206 ARD-ELTYSGALNGDIYVWK 224
             D +L  +G  +  ++VW+
Sbjct: 86  GLDPDLVMTGGSDASVHVWR 27

 Score = 32.0 bits (71), Expect = 2.2,   Method: Compositional matrix adjust.
 Identities = 17/51 (33%), Positives = 28/51 (54%)
 Frame = -1

Query: 120 RLVSVGLDSKNAVCVWDWKRGRMLSMAPGHTDRIFDISWDLYQPNKLVSCG 170
           RLVSVG D++    VWD ++G  L+   GH  R+    +    P+ +++ G
Sbjct: 200 RLVSVGYDAE--AFVWDVQKGTALAQFKGHMGRLLTCQFSGLDPDLVMTGG 54
>14500
          Length = 1238

 Score = 35.0 bits (79), Expect = 0.31,   Method: Compositional matrix adjust.
 Identities = 19/91 (20%), Positives = 41/91 (45%)
 Frame = +3

Query: 1458 VHIWDAVNKQTLSILRCSHSKGVCSVSFSATGKLLLSVGLDPEHTVTIWRWQEGAKIASR 1517
            +H W+      LS +       VC++ +S   + L+S     ++ + IW++   +++A  
Sbjct: 282  IHFWNCNTGTNLSSVDTK--SQVCALLWSKEHRELISSHGFAQNQLIIWKYPAMSRVAEL 455

Query: 1518 GGHNQRIFVAEFRPDSDTQFVSVGIKHVKFW 1548
             GH  R+      PD +T   +   + ++ W
Sbjct: 456  TGHTARVLHMAMSPDGETVVSAAADETLRLW 548

 Score = 32.7 bits (73), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 21/103 (20%), Positives = 47/103 (45%)
 Frame = +3

Query: 742 VATGQVGRDPSIHVWDTETIKPLSILKGYHQYGICAVDFSADGKRLASVGIDDSHTIVLW 801
           +A+G    D  IH W+  T   LS +    Q  +CA+ +S + + L S      + +++W
Sbjct: 249 LASGGGTADRHIHFWNCNTGTNLSSVDTKSQ--VCALLWSKEHRELISSHGFAQNQLIIW 422

Query: 802 DWKKGEKLSVTRGSKDKIFVVKMNPYVPDKLITAGIKHMKFWR 844
            +    +++   G   ++  + M+P     +  A  + ++ W+
Sbjct: 423 KYPAMSRVAELTGHTARVLHMAMSPDGETVVSAAADETLRLWK 551
>11678
          Length = 965

 Score = 34.3 bits (77), Expect = 0.51,   Method: Compositional matrix adjust.
 Identities = 18/73 (24%), Positives = 34/73 (46%), Gaps = 4/73 (5%)
 Frame = -3

Query: 774 GICAVDFSAD----GKRLASVGIDDSHTIVLWDWKKGEKLSVTRGSKDKIFVVKMNPYVP 829
           GIC   F+       KR+ S  + +SH   +WD    + +++    + +     +N Y  
Sbjct: 432 GICLXTFTPAXPL*AKRMHSQNVCESHRTXIWDXHLXKDINILEMVQRRAARFTLNNYXY 253

Query: 830 DKLITAGIKHMKF 842
           D  +T  +KH+K+
Sbjct: 252 DSSVTTMLKHLKW 214
>01768
          Length = 1424

 Score = 33.9 bits (76), Expect = 0.70,   Method: Compositional matrix adjust.
 Identities = 17/61 (27%), Positives = 32/61 (52%), Gaps = 2/61 (3%)
 Frame = +3

Query: 1912 LVTGDDFGMVKLYDFPC--PEKFAKHKRFLGHSPHVTNIRFTSGDRHVVSAGGDDCSLFV 1969
            L +G D G++K++D      +  +    F  HS  VT++ +   D  V++A G+D  + +
Sbjct: 1026 LASGGDDGIIKIWDLRMFRNKPVSAQASFKLHSQPVTSLEWNPQDSSVLAASGEDDQITI 1205

Query: 1970 W 1970
            W
Sbjct: 1206 W 1208

 Score = 32.0 bits (71), Expect = 2.6,   Method: Compositional matrix adjust.
 Identities = 15/62 (24%), Positives = 30/62 (48%)
 Frame = +3

Query: 1208 LATGDDLGFVKLFRYPAKGKFGKFKKYVAHSTHVTNVRWTYDDSMLVTLGGADMSLMVWT 1267
            L TGD  G + + +  + G   +   Y AH+  V +V+W+ ++  +      D +L +W 
Sbjct: 747  LVTGDCTGAIYISQPSSSGWTTEKSSYAAHTDSVEDVQWSPNEGNVFASCSVDRTLRIWN 926

Query: 1268 NE 1269
             +
Sbjct: 927  TQ 932
>15337
          Length = 860

 Score = 33.5 bits (75), Expect = 0.90,   Method: Compositional matrix adjust.
 Identities = 24/99 (24%), Positives = 50/99 (50%), Gaps = 1/99 (1%)
 Frame = -1

Query: 64  IISLALHP-ERVLVATGQVGKEPYICVWDSYTVQTVSVLKDVHTHGIACLAFDLDGQRLV 122
           I   A  P  R L   GQ G   ++ V++  +++ +  +K  +  G+ C+ +  DG+ +V
Sbjct: 320 ISEFAFSPCSRYLAVVGQDG---HLRVFNYNSMELIGTMKS-YFGGLLCVCWSPDGKYIV 153

Query: 123 SVGLDSKNAVCVWDWKRGRMLSMAPGHTDRIFDISWDLY 161
           + G D  + V VW +   R++    GH   +  +++D++
Sbjct: 152 TGGED--DLVTVWSFHEKRVVCRGHGHKSWVNVVAFDIH 42

 Score = 33.1 bits (74), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 22/84 (26%), Positives = 35/84 (41%)
 Frame = -1

Query: 999  GEVWGLATHPYLPICATVSDDKTLRIWDLSPSHCMLAVRKLKKGGRCCCFSPDGKALAVG 1058
            G +   A  P     A V  D  LR+++ +    +  ++    G  C C+SPDGK +  G
Sbjct: 326  GAISEFAFSPCSRYLAVVGQDGHLRVFNYNSMELIGTMKSYFGGLLCVCWSPDGKYIVTG 147

Query: 1059 LNDGSFLMANADTLEDLVSFHHRK 1082
                       D L  + SFH ++
Sbjct: 146  ---------GEDDLVTVWSFHEKR 102
>26107
          Length = 1338

 Score = 33.5 bits (75), Expect = 0.98,   Method: Compositional matrix adjust.
 Identities = 28/69 (40%), Positives = 36/69 (52%), Gaps = 6/69 (8%)
 Frame = -3

Query: 963  AISLGHGHILVGT--KNGEILEVDKSGPITLLVQGHME--GEVWGLATHPYLPIC--ATV 1016
            AIS    ++L G+    G I EVDK     L + GH E    V   +T     +C  ATV
Sbjct: 403  AISPDGKYLLSGSGRNTGVIWEVDKPNKRPLFLIGHTEDVSAVDWCSTD----VCKLATV 236

Query: 1017 SDDKTLRIW 1025
            SDD++LRIW
Sbjct: 235  SDDRSLRIW 209
>01249
          Length = 1743

 Score = 33.1 bits (74), Expect = 1.0,   Method: Compositional matrix adjust.
 Identities = 16/41 (39%), Positives = 23/41 (56%)
 Frame = -1

Query: 105 HTHGIACLAFDLDGQRLVSVGLDSKNAVCVWDWKRGRMLSM 145
           H+  + CLAF  DGQRL S   + K  V +W+ + G   S+
Sbjct: 918 HSDAVTCLAFSSDGQRLASGSQNGK--VIIWNMESGDSTSL 802
>20271
          Length = 567

 Score = 33.1 bits (74), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 23/83 (27%), Positives = 36/83 (43%), Gaps = 8/83 (9%)
 Frame = -1

Query: 1663 CVRSVCRGKGKILVGTRNSEIIEVGE--KNAACNILVNGHVDGPIWGLATHPS------R 1714
            C   +       +VG+    +         A  N    GH  GPI  + TH +       
Sbjct: 405  CFSFLSGDANNFIVGSEECLVYSASRHGSKAGINEAYEGH-QGPITAIDTHHAAGQIDFS 229

Query: 1715 DFFLSAAEDGTVRLWDIADKKML 1737
             FFL+A+ D TV+LW+I ++K +
Sbjct: 228  PFFLTASFDWTVKLWNIKEQKYV 160
>27465
          Length = 658

 Score = 32.7 bits (73), Expect = 1.7,   Method: Compositional matrix adjust.
 Identities = 26/116 (22%), Positives = 54/116 (46%), Gaps = 3/116 (2%)
 Frame = -1

Query: 242 SMNSCEEGFATGGRDGCIRLWDLTFKPITVIDLRETEQGYKGLSVRSVCWR---GDHILV 298
           + N     F TG  D   ++WD         +   T +G++ + V ++ +    GD ++ 
Sbjct: 340 AFNKSGSSFITGSYDRTCKIWD-----TASAEELHTLEGHRNV-VYAIAFNNPFGDKVIT 179

Query: 299 GTQDSEIFEIVVHERNKPFLIMQGHCEGELWALAVHPTKPLAVTGSDDRSVRIWSL 354
           G+ D +  ++      K +  ++GH   E+  ++ +P+  L  TGS D + R+W +
Sbjct: 178 GSFD-KTCKLWSTADGKCYHTLRGH-TAEIVCVSFNPSSTLIATGSMDTTCRLWDV 17

 Score = 30.8 bits (68), Expect = 5.2,   Method: Compositional matrix adjust.
 Identities = 33/120 (27%), Positives = 52/120 (43%), Gaps = 8/120 (6%)
 Frame = -1

Query: 715 RQQNTQRFYLGHDDDILCLAIHPLKDYVATGQVGR-------DPSIHVWDTETIKPLSIL 767
           R ++   FYL     +L   I PL + VA  + G        D +  +WDT + + L  L
Sbjct: 412 RPKDDHHFYLF---KVLRAHILPLTN-VAFNKSGSSFITGSYDRTCKIWDTASAEELHTL 245

Query: 768 KGYHQYGICAVDFSAD-GKRLASVGIDDSHTIVLWDWKKGEKLSVTRGSKDKIFVVKMNP 826
           +G H+  + A+ F+   G ++ +   D   T  LW    G+     RG   +I  V  NP
Sbjct: 244 EG-HRNVVYAIAFNNPFGDKVITGSFDK--TCKLWSTADGKCYHTLRGHTAEIVCVSFNP 74
>03426
          Length = 1202

 Score = 32.7 bits (73), Expect = 1.7,   Method: Composition-based stats.
 Identities = 18/48 (37%), Positives = 28/48 (58%), Gaps = 3/48 (6%)
 Frame = -2

Query: 1890 IWSRHAEKADVTCACVSHSGISLVTGDD---FGMVKLYDFPCPEKFAK 1934
            ++SR+AE   V+   +S + I  V+GDD      VK +  PCPE++ K
Sbjct: 268  LFSRNAEFCQVSMVSLSKTTI-FVSGDDPRIQAAVKFFKRPCPEEYEK 128
>15780
          Length = 735

 Score = 32.3 bits (72), Expect = 2.0,   Method: Compositional matrix adjust.
 Identities = 29/88 (32%), Positives = 43/88 (48%), Gaps = 2/88 (2%)
 Frame = -1

Query: 741 YVATGQVGRDPSIHVWDTETIKPLSILKGYHQYGICAVDFSADGKRLASVGIDDSHTIVL 800
           Y++T   G D ++ VWD  +   ++ L   H   + A+ FS DG  LAS G+D+S  I L
Sbjct: 732 YLSTA--GADHTVIVWDIASGTAVAHLTA-HTDTVYALCFSRDGTVLASGGMDNS--IRL 568

Query: 801 WDWKK--GEKLSVTRGSKDKIFVVKMNP 826
           WD  +   E+   T  +      V  NP
Sbjct: 567 WDLARVMEEQDPETDSNVPSSLSVNTNP 484

 Score = 31.6 bits (70), Expect = 3.3,   Method: Compositional matrix adjust.
 Identities = 20/58 (34%), Positives = 29/58 (50%)
 Frame = -1

Query: 82  GKEPYICVWDSYTVQTVSVLKDVHTHGIACLAFDLDGQRLVSVGLDSKNAVCVWDWKR 139
           G +  + VWD  +   V+ L   HT  +  L F  DG  L S G+D  N++ +WD  R
Sbjct: 717 GADHTVIVWDIASGTAVAHLT-AHTDTVYALCFSRDGTVLASGGMD--NSIRLWDLAR 553

 Score = 30.8 bits (68), Expect = 5.4,   Method: Compositional matrix adjust.
 Identities = 14/32 (43%), Positives = 20/32 (62%), Gaps = 2/32 (6%)
 Frame = -1

Query: 235 AHTAGIFSMNSCEEG--FATGGRDGCIRLWDL 264
           AHT  ++++    +G   A+GG D  IRLWDL
Sbjct: 654 AHTDTVYALCFSRDGTVLASGGMDNSIRLWDL 559
>14555
          Length = 627

 Score = 32.0 bits (71), Expect = 2.6,   Method: Composition-based stats.
 Identities = 20/68 (29%), Positives = 34/68 (50%), Gaps = 1/68 (1%)
 Frame = -2

Query: 721 RFYLGHDDDILCLAIHPLKDYVATGQVGRDPSIHVWDTETIKPLSILKGYH-QYGICAVD 779
           + + GH+ DI C+  +P  D  ATG    D +  ++D    + ++  +     +G  AVD
Sbjct: 617 QMFEGHEADINCVRFYPSGDAFATGS--DDATCRLFDLRADREVNCYRKESIIFGCNAVD 444

Query: 780 FSADGKRL 787
           FS  G+ L
Sbjct: 443 FSVSGRLL 420
>02147
          Length = 1547

 Score = 32.0 bits (71), Expect = 2.9,   Method: Compositional matrix adjust.
 Identities = 51/232 (21%), Positives = 87/232 (37%), Gaps = 51/232 (21%)
 Frame = +2

Query: 1639 AVKLWDQELRRCRAFRLETGQVTDCVRSV-CRGKGKILVGTRNSEIIEVGEKNAACNILV 1697
            + K+WD E    +   L+T      V+SV     G  L+   N ++++V +       LV
Sbjct: 242  SAKIWDAE----KGEELQTFSHKHIVKSVDFSHDGTALLTGSNEKLLKVFD-------LV 388

Query: 1698 NGHVDGPIWGLATHPSR---DFFLS-------AAEDGTVRLWDIADKKMLNKVNLGHAAR 1747
            N   D      A H S      FLS       A++D TVRLW +   + + ++       
Sbjct: 389  N--TDAEPKSFAGHTSNIKGALFLSDGKRIISASDDKTVRLWSLETCQEVQQLTFDTPPT 562

Query: 1748 TVCYSPEGDMVAIG---------------MKNGE---------------FIILLVSSLKI 1777
            ++  SP+ + + +                MK  E               F +      K+
Sbjct: 563  SLTLSPDKNTIIVTHSQNIAFYQADTLREMKKFEAEAPISSASLHQSERFFVAGGEDFKM 742

Query: 1778 W------GKK----RDRRCAIHDIRFSPDSRYLAVGSSENSVDFYDLTLGPT 1819
            +      GK+    +     +H +RFSPD    A GS + ++  +  T+G T
Sbjct: 743  YKFDYETGKEIESFKGHFGPVHCVRFSPDGELYASGSEDGTLRLWQTTIGRT 898

 Score = 31.2 bits (69), Expect = 4.3,   Method: Compositional matrix adjust.
 Identities = 66/288 (22%), Positives = 108/288 (37%), Gaps = 11/288 (3%)
 Frame = +2

Query: 994  QGHMEGEVWGLATHPYLPICATVSDDKTLRIWDLSPSHCMLAVRKLKKGGRCCCFSPDGK 1053
            +GH +G VWG   +      AT + D + +IWD       L     K   +   FS DG 
Sbjct: 164  EGH-KGAVWGATLNREATRAATGAADFSAKIWDAEKGE-ELQTFSHKHIVKSVDFSHDGT 337

Query: 1054 ALAVGLND---GSFLMANADTLEDLVSFH-HRKDIISDIRFSPGSGKYLAVASHDSFVDI 1109
            AL  G N+     F + N D   +  SF  H  +I   +  S   GK +  AS D  V +
Sbjct: 338  ALLTGSNEKLLKVFDLVNTDA--EPKSFAGHTSNIKGALFLS--DGKRIISASDDKTVRL 505

Query: 1110 YNVTSSKRVGVCKGATSYITHIDWDSRGKLLQVNTGAKEQLFFEAP------RGKRQTIP 1163
            +++ + + V                             +QL F+ P         + TI 
Sbjct: 506  WSLETCQEV-----------------------------QQLTFDTPPTSLTLSPDKNTII 598

Query: 1164 SVEVEKISWATWTSVLGL-CCEGIWPVIGEVTEVTASCLTSDKMVLATGDDLGFVKLFRY 1222
                + I++    ++  +   E   P+       +AS   S++  +A G+D    K F Y
Sbjct: 599  VTHSQNIAFYQADTLREMKKFEAEAPI------SSASLHQSERFFVAGGEDFKMYK-FDY 757

Query: 1223 PAKGKFGKFKKYVAHSTHVTNVRWTYDDSMLVTLGGADMSLMVWTNEV 1270
                +   FK    H   V  VR++ D  +  + G  D +L +W   +
Sbjct: 758  ETGKEIESFK---GHFGPVHCVRFSPDGELYAS-GSEDGTLRLWQTTI 889
>09883
          Length = 650

 Score = 31.2 bits (69), Expect = 3.9,   Method: Compositional matrix adjust.
 Identities = 26/106 (24%), Positives = 45/106 (42%)
 Frame = +3

Query: 67  LALHPERVLVATGQVGKEPYICVWDSYTVQTVSVLKDVHTHGIACLAFDLDGQRLVSVGL 126
           +AL P+   VA   +  +  +  WD+   + +  L  +H   I  LAFD     LV+ G 
Sbjct: 57  IALSPDGRTVA---ICSQSSVVFWDAVACEEMHTLHSLHAEPITALAFDNSNHYLVTCG- 224

Query: 127 DSKNAVCVWDWKRGRMLSMAPGHTDRIFDISWDLYQPNKLVSCGVK 172
                      K  +++   PG+   I D+   L++  K  S G++
Sbjct: 225 ----------DKHIQVIHNVPGYKTTIADL---LHREKKASSTGMR 323
>00825
          Length = 1821

 Score = 30.4 bits (67), Expect = 7.0,   Method: Compositional matrix adjust.
 Identities = 30/125 (24%), Positives = 53/125 (42%), Gaps = 2/125 (1%)
 Frame = -2

Query: 993  VQGHMEGEVWGLATHPYLPICATVSDDKTLRIWDLSPSHCMLAVRKLKKGGRCCCFSPDG 1052
            VQ H +G V G+A H       +   DKT++ W L P   +          +C   S D 
Sbjct: 1757 VQAH-DGIVHGMAAHSSGQYFFSCGSDKTIKQWSLDPEGTIAPEPVNTLLAKCIYTSLDH 1581

Query: 1053 K-ALAVGLNDGSFL-MANADTLEDLVSFHHRKDIISDIRFSPGSGKYLAVASHDSFVDIY 1110
                 + +  GS + + +    E + SF    + +  ++F+P     L  A+HD  + +Y
Sbjct: 1580 HWKDDIFVTSGSRVDVWDEKRSEPMRSFSWGVESVHHVKFNPVETYLLGAAAHDRSILLY 1401

Query: 1111 NVTSS 1115
            ++  S
Sbjct: 1400 DMRGS 1386
>26939
          Length = 388

 Score = 30.4 bits (67), Expect = 7.3,   Method: Compositional matrix adjust.
 Identities = 11/19 (57%), Positives = 14/19 (73%)
 Frame = +2

Query: 1015 TVSDDKTLRIWDLSPSHCM 1033
            + SDDKT+R+WDL    CM
Sbjct: 17   SASDDKTIRVWDLRNKRCM 73
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|12746424|ref|NP_075534.1| dihydropyrimidinase-like 5
[Mus musculus]
         (564 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

14768                                                                 203   3e-58
34622                                                                 143   2e-34
29305                                                                  37   0.024
>14768
          Length = 697

 Score =  203 bits (517), Expect(2) = 3e-58,   Method: Compositional matrix adjust.
 Identities = 95/167 (56%), Positives = 121/167 (72%)
 Frame = -1

Query: 309 YLMSLLANDTLNIVASDHRPFTTKQKAMGKEDFTKIPHGVSGVQDRMSVVWERGVVGGKM 368
           YLM LLAN+ L +  +D+  F   QKA+GK+DF  IP+GV+GV+DRMSV+WE+GV  GKM
Sbjct: 505 YLMDLLANNDLQVTGTDNCTFRADQKALGKDDFRSIPNGVNGVEDRMSVIWEKGVQSGKM 326

Query: 369 DENRFVAVTSSNAAKILNLYPRKGRIIPGADADVVVWDPEATKTISASTQVQGGDFNLYE 428
           D  RFVAVTSS AAKI N+YPRKGRI  G+DADVVVWD   T+TISA T  Q  DFN++E
Sbjct: 325 DACRFVAVTSSAAAKIFNIYPRKGRIAVGSDADVVVWDGNQTRTISAETHHQAVDFNIFE 146

Query: 429 NMRCHGVPLVTISRGRVVYENGVFMCAEGTGKFCPLRSFPDIVYKKL 475
            ++CHGVP+  I  G VV +NG     +G+G+F P   FP+ VY ++
Sbjct: 145 GLQCHGVPVYVIXNGNVVVDNGEVKVTKGSGRFIPSPCFPEAVYGRI 5

 Score = 40.8 bits (94), Expect(2) = 3e-58,   Method: Compositional matrix adjust.
 Identities = 20/51 (39%), Positives = 32/51 (62%)
 Frame = -2

Query: 245 LVNVSSISAGDVIAAAKMQGKVVLAETTNAHATLTGLHYYHQDWSHAAAYV 295
           +V++ S S+ DVI+A++ +GKVV  E   A     G H +++ W HAA +V
Sbjct: 696 VVHIMSKSSADVISASRRKGKVVFGEPIAASLGTDGTHQWNRCWRHAAGHV 544
>34622
          Length = 477

 Score =  143 bits (360), Expect = 2e-34,   Method: Compositional matrix adjust.
 Identities = 66/128 (51%), Positives = 90/128 (70%)
 Frame = -3

Query: 353 DRMSVVWERGVVGGKMDENRFVAVTSSNAAKILNLYPRKGRIIPGADADVVVWDPEATKT 412
           DRMSV+WE+GV+ GKMD  RFVA TS+NAA+I N+YPRKGRI  G+DADVVVWD   T+T
Sbjct: 475 DRMSVIWEKGVMMGKMDACRFVAATSANAARIYNIYPRKGRIAVGSDADVVVWDGNQTRT 296

Query: 413 ISASTQVQGGDFNLYENMRCHGVPLVTISRGRVVYENGVFMCAEGTGKFCPLRSFPDIVY 472
           ISA T  Q  DFN++E ++CHGVP+  +S G+VV ++G     +G G+        + VY
Sbjct: 295 ISAETHHQAVDFNIFEGLQCHGVPVYVVSNGQVVVDDGQLKVTQGLGRLVSTPCNAETVY 116

Query: 473 KKLVQREK 480
            ++  R++
Sbjct: 115 GRVKARDQ 92
>29305
          Length = 881

 Score = 37.0 bits (84), Expect = 0.024,   Method: Compositional matrix adjust.
 Identities = 17/23 (73%), Positives = 18/23 (78%)
 Frame = -3

Query: 80  DDFYHGTKAALVGGTTMIIGHVL 102
           DDFY GTKAAL GGTTMI+  V 
Sbjct: 876 DDFYIGTKAALAGGTTMIMDFVF 808
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31982332|ref|NP_032157.2| glutamine synthetase [Mus
musculus]
         (373 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

20697                                                                 221   4e-58
35005                                                                 150   6e-37
12588                                                                  31   0.76 
06128                                                                  30   1.5  
12337                                                                  28   8.7  
>20697
          Length = 409

 Score =  221 bits (563), Expect = 4e-58,   Method: Compositional matrix adjust.
 Identities = 101/136 (74%), Positives = 117/136 (86%)
 Frame = +1

Query: 188 VKITGTNAEVMPAQWEFQIGPCEGIRMGDHLWIARFILHRVCEDFGVIATFDPKPIPGNW 247
           VKI G NAEVMPAQWEFQ+GPCEGI+MGDHLWIAR+I+HRV EDFGV+ T DPKP+ G+W
Sbjct: 1   VKIAGCNAEVMPAQWEFQVGPCEGIQMGDHLWIARYIMHRVAEDFGVVVTLDPKPMEGDW 180

Query: 248 NGAGCHTNFSTKAMREENGLKCIEEAIDKLSKRHQYHIRAYDPKGGLDNARRLTGFHETS 307
           NGAG H N+ST AMRE  G+K IE+AIDKLS+ H  HI+AYDP+ G DN RRLTG HETS
Sbjct: 181 NGAGAHCNYSTLAMREAGGVKEIEKAIDKLSRHHVRHIKAYDPREGKDNERRLTGHHETS 360

Query: 308 NINDFSAGVANRGASI 323
           +I+DFSAGVANRG+SI
Sbjct: 361 SIHDFSAGVANRGSSI 408
>35005
          Length = 445

 Score =  150 bits (380), Expect = 6e-37,   Method: Compositional matrix adjust.
 Identities = 70/98 (71%), Positives = 81/98 (82%)
 Frame = +2

Query: 266 GLKCIEEAIDKLSKRHQYHIRAYDPKGGLDNARRLTGFHETSNINDFSAGVANRGASIRI 325
           GL  IEEAI KLSK+H+ HIRAYDP  G DN RRLTG HETS+INDFSAGVANRGASIRI
Sbjct: 2   GLSIIEEAISKLSKKHEDHIRAYDPNQGEDNRRRLTGLHETSSINDFSAGVANRGASIRI 181

Query: 326 PRTVGQEKKGYFEDRRPSANCDPYAVTEAIVRTCLLNE 363
           PR V ++  GY EDRRPS+NCDPY+VTE +V+T +L +
Sbjct: 182 PRQVAEDGFGYLEDRRPSSNCDPYSVTEILVKTTMLED 295
>12588
          Length = 634

 Score = 31.2 bits (69), Expect = 0.76,   Method: Compositional matrix adjust.
 Identities = 29/125 (23%), Positives = 46/125 (36%), Gaps = 5/125 (4%)
 Frame = +1

Query: 97  VLCEVFKYNRKPAETNLRHICKRIMDMVSNQHPWF---GMEQEYTLMGTDGHPFGWPSNG 153
           VLC+++  +  P     R + K  +D +   H      G E E+         F +  N 
Sbjct: 193 VLCDMYMPDGSPDLHCPRQLLKTQLDALRKNHGLVVKTGFEYEF---------FVYKENT 345

Query: 154 FPGPQGPYYCGVGADKAYG--RDIVEAHYRACLYAGVKITGTNAEVMPAQWEFQIGPCEG 211
              P G         + +G  +DI           G+K++   AE  P QWE    P +G
Sbjct: 346 L-EPLGSQSLQFADLRVWGEHQDIFSELREMLESMGIKVSTFQAEFAPGQWEVTTIPYDG 522

Query: 212 IRMGD 216
           +   D
Sbjct: 523 LHGAD 537
>06128
          Length = 1202

 Score = 30.0 bits (66), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 14/35 (40%), Positives = 17/35 (48%)
 Frame = -3

Query: 34  DGTGEGLRCKTRTLDCEPKCVEELPEWNFDGSSTF 68
           +GT   L    R L C P CV E+P W  D   +F
Sbjct: 300 EGTAWPL---ARPLQCRPLCVXEIPSWRRDQHPSF 205
>12337
          Length = 1238

 Score = 27.7 bits (60), Expect = 8.7,   Method: Compositional matrix adjust.
 Identities = 11/26 (42%), Positives = 17/26 (65%)
 Frame = -2

Query: 259 KAMREENGLKCIEEAIDKLSKRHQYH 284
           K  +   G+KC+ + IDK  K+H+YH
Sbjct: 787 KIYKSPKGIKCLIKIIDKALKKHRYH 710
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|89337277|ref|NP_067512.3| serine/threonine kinase 25
[Mus musculus]
         (426 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

18921                                                                 221   5e-58
13212                                                                 199   2e-51
19094                                                                 152   1e-49
14420                                                                 163   1e-40
12721                                                                 160   8e-40
00300                                                                 122   2e-28
13592                                                                 110   9e-25
37602                                                                 105   5e-23
01718                                                                  99   4e-21
01707                                                                  92   5e-19
06405                                                                  91   7e-19
14126                                                                  90   1e-18
31885                                                                  90   2e-18
09606                                                                  89   3e-18
19761                                                                  86   4e-17
30755                                                                  81   7e-16
18484                                                                  79   3e-15
15910                                                                  79   5e-15
29581                                                                  79   5e-15
03240                                                                  78   7e-15
07291                                                                  78   7e-15
21808                                                                  77   1e-14
04852                                                                  76   3e-14
13066                                                                  72   5e-13
02638                                                                  72   5e-13
27405                                                                  70   1e-12
00715                                                                  70   1e-12
26560                                                                  69   3e-12
21079                                                                  67   3e-12
01756                                                                  69   4e-12
01392                                                                  69   4e-12
07940                                                                  68   5e-12
09007                                                                  68   6e-12
27546                                                                  66   3e-11
12786                                                                  66   3e-11
00392                                                                  65   4e-11
14116                                                                  65   4e-11
04591                                                                  64   8e-11
21210                                                                  64   1e-10
21433                                                                  64   2e-10
01060                                                                  63   3e-10
11780                                                                  62   3e-10
28638                                                                  60   2e-09
19301                                                                  59   4e-09
26711                                                                  57   1e-08
07836                                                                  55   4e-08
17975                                                                  55   5e-08
03508                                                                  55   5e-08
11185                                                                  55   5e-08
18996                                                                  54   1e-07
04138                                                                  54   1e-07
17300                                                                  54   1e-07
20825                                                                  53   2e-07
14477                                                                  52   4e-07
25019                                                                  51   7e-07
01966                                                                  51   8e-07
12672                                                                  51   1e-06
20640                                                                  50   2e-06
17253                                                                  49   3e-06
07833                                                                  48   8e-06
14326                                                                  47   1e-05
28411                                                                  47   2e-05
28157                                                                  46   3e-05
18663                                                                  44   1e-04
16708                                                                  44   2e-04
29590                                                                  37   4e-04
06358                                                                  42   5e-04
17516                                                                  42   5e-04
31489                                                                  41   0.001
20152                                                                  40   0.003
38560                                                                  40   0.003
13840                                                                  39   0.004
00486                                                                  39   0.005
26009                                                                  38   0.006
22005                                                                  36   0.025
32691                                                                  36   0.028
17637                                                                  35   0.048
18401                                                                  35   0.054
01106                                                                  35   0.057
32957                                                                  35   0.081
37063                                                                  34   0.10 
18481                                                                  33   0.32 
13305                                                                  32   0.34 
00394                                                                  31   0.76 
32000                                                                  31   1.2  
29011                                                                  30   1.6  
31789                                                                  30   1.7  
32357                                                                  30   1.7  
16350                                                                  30   1.8  
08233                                                                  29   3.2  
11541                                                                  29   3.8  
03106                                                                  29   3.9  
00638                                                                  29   4.7  
29722                                                                  28   5.4  
18929                                                                  28   5.6  
>18921
          Length = 697

 Score =  221 bits (562), Expect = 5e-58,   Method: Compositional matrix adjust.
 Identities = 115/228 (50%), Positives = 145/228 (63%), Gaps = 8/228 (3%)
 Frame = +2

Query: 16  PEELFTKLDRIGKGSFGEVYKGIDNHTKEVVXXXXXXXXXXXXXXXXXXXXXTVLSQCDS 75
           PE++F  L ++G+GS+G V+K +   T +V+                     +++ QCDS
Sbjct: 23  PEDVFDILGKLGEGSYGSVFKSLHKETGQVLAIKQVPVDTDLQEIIKEI---SIMQQCDS 193

Query: 76  PYITRYFGSYLKSTKLWIIMEYLGGGSALDL--LKPGPLEETYIATILREILKGLDYLHS 133
            YI +Y+GSY K+T LWI+MEY G GS  D+  L+   L E  IATIL   LKGL YLHS
Sbjct: 194 KYIVKYYGSYFKNTDLWIVMEYCGAGSVSDIMRLRNKTLVEREIATILYYTLKGLXYLHS 373

Query: 134 ERKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYD 193
            RKIHRDIKA N+LL+ +G  KLADFGVAGQLTDT  KRNT +GTP+WMAPEVI++  YD
Sbjct: 374 RRKIHRDIKAGNILLNNEGHAKLADFGVAGQLTDTMAKRNTVIGTPYWMAPEVIQEIGYD 553

Query: 194 FKADIWSLGITAIELAKGEPPNSDLHPMRVLFL------IPKNNPPTL 235
             ADIWSLGITA+E+A+G+PP      M    L       P N PP L
Sbjct: 554 CVADIWSLGITALEMAEGKPP-----VMETSIL*GQSS*FPTNAPPPL 682
>13212
          Length = 1067

 Score =  199 bits (506), Expect = 2e-51,   Method: Compositional matrix adjust.
 Identities = 100/196 (51%), Positives = 131/196 (66%), Gaps = 12/196 (6%)
 Frame = -1

Query: 91   LWIIME-----YLGGGSALDLLKPGPLEETYIATILREILKGLDYLHSERKIHRDIKAAN 145
            +W I++     + G   ++ +    P+ E  I  +  E+   LD+LH    IHRDIKA N
Sbjct: 1067 VWXIVDVFRVLWWGALDSIMVDLEKPMTEAQICYVCHEMCMALDFLHRHHVIHRDIKAGN 888

Query: 146  VLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVI-----KQSAYDFKADIWS 200
            VLL+  G+VKLADFGV+ + T TQ KR+TF+GTP+WMAPEV+     K + YDFKADIWS
Sbjct: 887  VLLTIDGEVKLADFGVSAKNTQTQQKRDTFIGTPYWMAPEVVLCETLKDTPYDFKADIWS 708

Query: 201  LGITAIELAKGEPPNSDLHPMRVLFLIPKNNPPTLEGHH--SKPFKEFVEACLNKDPRFR 258
            LG+T IE A+ EPPN ++HPMRVL  I K++PPTLE     +K FK+F+  CL KDP  R
Sbjct: 707  LGVTLIEFAQIEPPNKEMHPMRVLIKIHKSDPPTLEKPKKWTKLFKDFIAKCLVKDPNLR 528

Query: 259  PTAKELLKHKFITRYT 274
            PTA ELL+H F+ R T
Sbjct: 527  PTAAELLEHPFMKRAT 480
>19094
          Length = 898

 Score =  152 bits (384), Expect(2) = 1e-49,   Method: Compositional matrix adjust.
 Identities = 76/116 (65%), Positives = 88/116 (75%), Gaps = 2/116 (1%)
 Frame = +1

Query: 99  GGGSALDL--LKPGPLEETYIATILREILKGLDYLHSERKIHRDIKAANVLLSEQGDVKL 156
           G GS  D+  L+   L E  IATIL   LKGL YLHS RKIHRDIKA N+LL+ +G  KL
Sbjct: 4   GAGSVSDIMRLRNKTLVEREIATILYYTLKGL*YLHSRRKIHRDIKAGNILLNNEGHAKL 183

Query: 157 ADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDFKADIWSLGITAIELAKGE 212
           ADFGVAGQLTDT  KRNT +GTP+WMAPEVI++  YD  ADIWSLGITA+E+A+G 
Sbjct: 184 ADFGVAGQLTDTMAKRNTVIGTPYWMAPEVIQEIGYDCVADIWSLGITALEMAEGN 351

 Score = 62.4 bits (150), Expect(2) = 1e-49,   Method: Compositional matrix adjust.
 Identities = 29/66 (43%), Positives = 40/66 (60%), Gaps = 2/66 (3%)
 Frame = +3

Query: 209 AKGEPPNSDLHPMRVLFLIPKNNPPTLE--GHHSKPFKEFVEACLNKDPRFRPTAKELLK 266
            +G+PP  D+HPMR +F+IP   PP+       S  F +FV  CL K+P  R TA +LL+
Sbjct: 339 GRGKPPYGDIHPMRAIFMIPTKPPPSFRQPDKWSTEFIDFVSKCLVKNPENRATAVDLLQ 518

Query: 267 HKFITR 272
           H FI +
Sbjct: 519 HDFIKK 536
>14420
          Length = 528

 Score =  163 bits (412), Expect = 1e-40,   Method: Compositional matrix adjust.
 Identities = 73/156 (46%), Positives = 102/156 (65%)
 Frame = +2

Query: 69  VLSQCDSPYITRYFGSYLKSTKLWIIMEYLGGGSALDLLKPGPLEETYIATILREILKGL 128
           V+ +  +P I  Y  SYL   +LW++ME+L GGS  D++    ++E  IA + RE L+ L
Sbjct: 59  VMRENQNPNIVNYLDSYLVGEELWVVMEFLAGGSLTDVVTETCMDEGQIAAVCRECLQAL 238

Query: 129 DYLHSERKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIK 188
           ++LH  + IHRDIK+ N+LL   G VKL DFG   QL+  Q KR+T VGTP+WMAPEV+ 
Sbjct: 239 EFLHENQVIHRDIKSDNILLGMDGSVKLTDFGFCAQLSPEQSKRSTMVGTPYWMAPEVVT 418

Query: 189 QSAYDFKADIWSLGITAIELAKGEPPNSDLHPMRVL 224
           +  Y    DIWSLG+  IE+ +GEPP  + +P+R L
Sbjct: 419 RKQYGPTVDIWSLGVMCIEMIEGEPPYLNENPLRAL 526
>12721
          Length = 821

 Score =  160 bits (406), Expect = 8e-40,   Method: Compositional matrix adjust.
 Identities = 88/249 (35%), Positives = 127/249 (51%), Gaps = 2/249 (0%)
 Frame = +1

Query: 15  DPEELFTKLDRIGKGSFGEVYKGIDNHTKEVVXXXXXXXXXXXXXXXXXXXXXTVLSQCD 74
           DP        +IG+GS G V        +++                       V+    
Sbjct: 79  DPRTFLDDFMKIGEGSTGIVCIATSRDGRQMAVKKMDLRKQQRRELLFNEV--VVMRDYH 252

Query: 75  SPYITRYFGSYLKSTKLWIIMEYLGGGSALDLLKPGPLEETYIATILREILKGLDYLHSE 134
            P I   + SYL + +LW++ME++ GG+  D++    ++E  IAT+ R  LK L +LH+ 
Sbjct: 253 HPNIVEMYNSYLVNDELWVVMEFMEGGALTDIVTNNRMDEVQIATVCRACLKALAFLHAN 432

Query: 135 RKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDF 194
             IHRDIK+ ++LLS  G VKL DFG   Q+T    KR + VGTP+WMAPEVI +  Y  
Sbjct: 433 GVIHRDIKSDSILLSHDGKVKLXDFGFCAQVTQDLQKRKSLVGTPYWMAPEVISRLPYGP 612

Query: 195 KADIWSLGITAIELAKGEPPNSDLHPMRVLFLIPKNNPPTLEGHH--SKPFKEFVEACLN 252
           + DIWSLGI  +E+   EPP  +  P++ +  I    PP L   H  S   + F++  L 
Sbjct: 613 EVDIWSLGIMVMEMIDAEPPFFNEPPLQAMRRIRDMPPPKLRNTHKISPRLQGFIDRMLV 792

Query: 253 KDPRFRPTA 261
           +DP  R TA
Sbjct: 793 RDPHQRATA 819
>00300
          Length = 2318

 Score =  122 bits (307), Expect = 2e-28,   Method: Compositional matrix adjust.
 Identities = 79/259 (30%), Positives = 124/259 (47%), Gaps = 8/259 (3%)
 Frame = -1

Query: 24   DRIGKGSFGEVYKGIDNHTKEVVXXXXXXXX-XXXXXXXXXXXXXTVLSQCDSPYITRYF 82
            ++IG+G FG+VY  ++  T E++                       +        + +Y+
Sbjct: 1640 NKIGEGQFGKVYTAVNMSTGELMALKEMKFQPNDLQQLREMCDEIKIFEGIQHENLVKYY 1461

Query: 83   GSYLKSTKLWIIMEYLGGGSALDLLKPGPLEETYIATILREILKGLDYLHSERKIHRDIK 142
            G  +   ++ + MEY   G+  +  K G L E  I    REI+  +++LH    +HRDIK
Sbjct: 1460 GVEVHKDEMLMFMEYCDTGTIEEAAKMG-LPEYLIRRYTREIVLAVNHLHENSIVHRDIK 1284

Query: 143  AANVLLSEQGDVKLADFGVAGQL---TDTQIKRNTFVGTPFWMAPEVIKQS---AYDFKA 196
             AN+ L+  G VKL DFG + +L   T    + +  VGT  +MAPEV  Q+    Y   A
Sbjct: 1283 GANIFLTSNGHVKLGDFGCSVKLKSHTTMPGEFHNLVGTTAYMAPEVFTQNDQGGYGRAA 1104

Query: 197  DIWSLGITAIELAKGEPPNSDL-HPMRVLFLIPKNNPPTLEGHHSKPFKEFVEACLNKDP 255
            DIWSLG   IE+A G+ P  DL +  ++++ +   + P +    S   K F++  +  DP
Sbjct: 1103 DIWSLGCVVIEMATGKRPWHDLDNNYQIMYKVGIGHKPAVPDSLSVEGKHFLDLIMCHDP 924

Query: 256  RFRPTAKELLKHKFITRYT 274
              R  A +LL H F   Y 
Sbjct: 923  AQRALASQLLDHTFTKVYN 867
>13592
          Length = 980

 Score =  110 bits (276), Expect = 9e-25,   Method: Compositional matrix adjust.
 Identities = 75/255 (29%), Positives = 122/255 (47%), Gaps = 10/255 (3%)
 Frame = +2

Query: 25  RIGKGSFGEVYKGIDNHTKEVVXXXXXXXX-XXXXXXXXXXXXXTVLSQCDSPYITRYFG 83
           +IG+G FG+VY  ++N+T E++                       +L       + RY+G
Sbjct: 5   KIGQGRFGKVYTAVNNNTGELMAMKEIAIQPGETRALKNVAEELKILEGIKHKNLVRYYG 184

Query: 84  SYLKSTKLWIIMEYLGGGSALDLLK-PGPLEETYIATILREILKGLDYLHSERKIHRDIK 142
             +   +L I ME    G+   L++  G L E        ++L G+  LH    +HRDIK
Sbjct: 185 IEVHREELLIFMELCSEGTLESLVELTGGLPEALSRRFTAQLLSGVAELHKHGIVHRDIK 364

Query: 143 AANVLLSEQGD-VKLADFGVAGQL---TDTQIKRNTFVGTPFWMAPEVIKQSAYDFK--- 195
            AN+ L +  + +KL DFG A ++   T    +   +VGT  +MAPEV  ++  D     
Sbjct: 365 TANIFLVDGSNSLKLGDFGSAVKIQAHTTVPGELQGYVGTQAYMAPEVFTKTNSDGHGRL 544

Query: 196 ADIWSLGITAIELAKGEPPNSDLHP-MRVLFLIPKNNPPTLEGHHSKPFKEFVEACLNKD 254
           ADIWS+G   +E+A G+ P +      +++F +     P      S+   +F++ CL  D
Sbjct: 545 ADIWSVGCVVVEMASGKRPWAQFDSNFQIMFKVGMGEKPQAPESLSQEGHDFIDHCLQHD 724

Query: 255 PRFRPTAKELLKHKF 269
           P+ R +A ELL+  F
Sbjct: 725 PKQRLSAIELLEQNF 769
>37602
          Length = 804

 Score =  105 bits (261), Expect = 5e-23,   Method: Compositional matrix adjust.
 Identities = 55/106 (51%), Positives = 66/106 (62%), Gaps = 6/106 (5%)
 Frame = -1

Query: 81  YFGSYLKSTKLWIIMEYLGGGSALDLLK-PGPLEETYIATILREILKGLDYLHSERKIHR 139
           YF SYL+  KLWI MEY GGGS  D+    GPL E  IA + RE LKGL YLH   K+HR
Sbjct: 324 YFDSYLRREKLWIAMEYCGGGSMQDIYHVTGPLTEPQIAFVCRETLKGLHYLHRRGKMHR 145

Query: 140 DIKAANVLLSEQGDVKLADFGVAGQLTDTQIKR-----NTFVGTPF 180
           DIK AN+LL+E+GDVKLADF          +++     N F+G P 
Sbjct: 144 DIKGANILLTEEGDVKLADFWRVSSNHSHNVQKKVFHWNAFIGWPL 7

 Score = 45.4 bits (106), Expect(2) = 2e-06,   Method: Compositional matrix adjust.
 Identities = 17/27 (62%), Positives = 22/27 (81%)
 Frame = -1

Query: 157 ADFGVAGQLTDTQIKRNTFVGTPFWMA 183
           ADFGV+ Q+T T  KR +F+GTP+WMA
Sbjct: 747 ADFGVSAQITATMCKRKSFIGTPYWMA 667

 Score = 24.3 bits (51), Expect(2) = 2e-06,   Method: Compositional matrix adjust.
 Identities = 11/18 (61%), Positives = 14/18 (77%), Gaps = 3/18 (16%)
 Frame = -2

Query: 145 NVLLSEQGDVK---LADF 159
           N+LL+E+GDVK   L DF
Sbjct: 803 NILLTEEGDVKLVCLCDF 750

 Score = 32.7 bits (73), Expect = 0.26,   Method: Compositional matrix adjust.
 Identities = 14/35 (40%), Positives = 20/35 (57%)
 Frame = -2

Query: 150 EQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAP 184
           ++G      FGV+ Q+T T  KR +F+GTP    P
Sbjct: 113 KKGTSSWRTFGVSAQITATMCKRKSFIGTPLLDGP 9
>01718
          Length = 959

 Score = 98.6 bits (244), Expect = 4e-21,   Method: Compositional matrix adjust.
 Identities = 72/259 (27%), Positives = 119/259 (45%), Gaps = 12/259 (4%)
 Frame = +3

Query: 20  FTKLD-----RIGKGSFGEVYKGIDNHTKEVVXXXXXXXXXXXXXXXXXXXXXTVLSQCD 74
            T+LD     +IG G F EV+K     T +V+                      +L++  
Sbjct: 138 LTRLDDFICEKIGAGFFSEVFKVTHRITGQVMALKMNTMTSNRHNMLREVQ---LLNRLQ 308

Query: 75  SPYITRYFGSYLKSTKLWIIMEYLGGGSALDLL--KPGPLEETYIATILREILKGLDYLH 132
              I R+ G  +   +L  + EY+  G+   LL  K   L  T    +   + +GLDYLH
Sbjct: 309 HANILRFMGVCVHEGQLHALTEYIPSGNLEQLLEKKDEELPWTQRIQLTLGLARGLDYLH 488

Query: 133 SERKIHRDIKAANVLLSEQGD----VKLADFGVAGQLTDTQIKRNT-FVGTPFWMAPEVI 187
           S R IHRD+ + N+L+  + +      +ADFG+A ++ D   K     VG+P+WMAPEV+
Sbjct: 489 STRFIHRDLTSKNILIRREDNHGYHAVIADFGLATKIPDPLDKEKLPTVGSPYWMAPEVL 668

Query: 188 KQSAYDFKADIWSLGITAIELAKGEPPNSDLHPMRVLFLIPKNNPPTLEGHHSKPFKEFV 247
               Y+ +AD++S+GI   E+    P + D+ P    F +       +  +    + +  
Sbjct: 669 NGHFYNERADLFSVGIIMCEITARIPADPDIMPRMNNFGVDYVALSEMISYCPLDYLQLA 848

Query: 248 EACLNKDPRFRPTAKELLK 266
             C   DP+ RP   E+++
Sbjct: 849 FKCCQVDPQKRPRGVEIIE 905
>01707
          Length = 757

 Score = 91.7 bits (226), Expect = 5e-19,   Method: Compositional matrix adjust.
 Identities = 60/219 (27%), Positives = 105/219 (47%), Gaps = 6/219 (2%)
 Frame = +1

Query: 12  SRVDPEELFTKLDRIGKGSFGEVYKGIDNHTKEVVXXXXXXXXXXX-XXXXXXXXXXTVL 70
            RVD  E + K+ +IG+GS+G V+K  +  T ++V                       +L
Sbjct: 46  DRVDRMEKYEKIGKIGEGSYGVVFKCRNKETSQLVAIKKFVESEDDPLIKKIAMREIRML 225

Query: 71  SQCDSPYITRYFGSYLKSTKLWIIMEYLGGGSALDLLK-PGPLEETYIATILREILKGLD 129
            Q   P + R    + +  +L ++ +Y+      +L + P  L E  +  I+ + L  ++
Sbjct: 226 KQLKHPNLVRLIEVFRRKKRLHLVFDYVDHTLLNELDRYPRGLPEPMVKRIIYQTLLAVN 405

Query: 130 YLHSERKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPE-VIK 188
           + H    IHRD+K  N+L++ QG VKL DFG A  LT    +   +V T ++ APE ++ 
Sbjct: 406 FCHQYNTIHRDVKPENILITRQGQVKLCDFGFARILTGPGDEYTDYVATRWYRAPELLVG 585

Query: 189 QSAYDFKADIWSLGITAIELAKGE---PPNSDLHPMRVL 224
            + Y    D+W++G    EL  G+   P  SD+  + ++
Sbjct: 586 DTQYGPPVDVWAIGCVFAELLTGQALWPGRSDVDQLHLI 702
>06405
          Length = 1965

 Score = 91.3 bits (225), Expect = 7e-19,   Method: Compositional matrix adjust.
 Identities = 70/271 (25%), Positives = 121/271 (44%), Gaps = 12/271 (4%)
 Frame = +1

Query: 25  RIGKGSFGEVYKGIDNHTKEVVXXXXXXXXXXXXXXXXXXXXXTVLSQCDSPYITRYFGS 84
           R+G G +G+VY+ +     ++V                      ++ +   P + +  G 
Sbjct: 280 RLGGGQYGDVYEAMWKRYNKIVAVKTLKEDTMALNDFLEEA--AIMKEMKHPNLVQLLGV 453

Query: 85  YLKSTKLWIIMEYLGGGSALDLLKP------GPLEETYIATILREILKGLDYLHSERKIH 138
             +    +I+ E++  G+ LD L+       GP    Y+AT   +I  G+ YL ++  IH
Sbjct: 454 CTREPPFYIVTEFMPHGNLLDYLRSSTREENGPTALMYMAT---QIASGMAYLETKNFIH 624

Query: 139 RDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPF---WMAPEVIKQSAYDFK 195
           RD+ A N L+++   VK+ADFG+A  + D        +G  F   W APE +  + +  +
Sbjct: 625 RDLAARNCLVADSNMVKVADFGLARLMKDDTY--TAHIGAKFPIKWTAPEGLAFNRFSTR 798

Query: 196 ADIWSLGITAIELAK-GEPPNSDLHPMRVLFLIPKNNPPTLEGHHSKPFKEFVEA--CLN 252
           +DIW+ G+   ELA  G  P   +    V  L+ +     +E     P   ++    C  
Sbjct: 799 SDIWAFGVLLWELATYGMSPYPGVELTEVYHLLERGY--RMERPPGTPADVYILMLKCWQ 972

Query: 253 KDPRFRPTAKELLKHKFITRYTKKTSFLTEL 283
            DP+ RPT KE+  H  +    +K+S   E+
Sbjct: 973 WDPKDRPTFKEI--HFLLENMFEKSSICEEV 1059
>14126
          Length = 1265

 Score = 90.1 bits (222), Expect = 1e-18,   Method: Compositional matrix adjust.
 Identities = 82/297 (27%), Positives = 131/297 (44%), Gaps = 20/297 (6%)
 Frame = +3

Query: 13  RVDPEELFTKLDRIGKGSFGEVYKGID--NHTKEVVXXXXXXXXXXXXXXXXXXXXXTVL 70
           R   E+ + ++  IG G++G VYK  D  N  + V                      ++L
Sbjct: 174 RDSTEQKYEEVAVIGNGAYGTVYKARDLRNQGEFVAMKRIRLNNTEEGMPMMAIREISML 353

Query: 71  SQCDS---PYITRYFGS-----YLKSTKLWIIMEYLGGGSALDLLK-PGP-LEETYIATI 120
            Q +    P + R           +  +L ++ EY+    A  L K P P L    I  +
Sbjct: 354 KQLEQYEHPNVVRLLDVSHNTITDREIRLNLVFEYIEHDLATYLAKCPSPGLGPDRIKDL 533

Query: 121 LREILKGLDYLHSERKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPF 180
           + ++L G+D+LHS R +HRD+K  N+L+S+ G +KLADFG+A ++    +   T V T +
Sbjct: 534 MLQLLNGVDFLHSNRIVHRDLKPQNLLISKDGRLKLADFGLA-RIYSFHMALTTVVVTLW 710

Query: 181 WMAPEVIKQSAYDFKADIWSLGITAIE------LAKGEPPNSDLHPM-RVLFLIPKNNPP 233
           + +PEV+ Q+ Y    DIWS G    E      L KG      L  +  V+ L P  + P
Sbjct: 711 YRSPEVLMQAEYGTSVDIWSCGCIFAELFTRRALFKGSSEFDQLKKIFEVIGLPPAGDWP 890

Query: 234 TLEGHHSKPFKEFVEACLNK-DPRFRPTAKELLKHKFITRYTKKTSFLTELIDRYKR 289
                H   F+      L    P   P AK+L++   + +  ++ S    L+  Y R
Sbjct: 891 EGVSVHRNSFRPTPPVPLQTLVPEMDPQAKDLMEKMLVFKSGRRISSRESLLHPYLR 1061
>31885
          Length = 529

 Score = 89.7 bits (221), Expect = 2e-18,   Method: Compositional matrix adjust.
 Identities = 54/164 (32%), Positives = 88/164 (53%), Gaps = 11/164 (6%)
 Frame = -2

Query: 69  VLSQCDSPYITRYFGSYLKSTKLWIIME-YLGGGSALDLLKPGPLEETYIATILREILKG 127
           +L++ D P++   + ++     L+++++ +LGG     + +     E  +   L ++   
Sbjct: 513 MLTRLDHPFLVNLWYAFQDEEDLFMVVDLFLGGDLRYHMQQEVSFREDCVKFYLCQLALV 334

Query: 128 LDYLHSERKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVI 187
           LDYL S++ +HRDIK  N+LL EQG   + DF +A QL D ++  +T  GT  +MAPEV 
Sbjct: 333 LDYLRSQKIVHRDIKPDNILLDEQGHCHVTDFNIATQLEDDELATST-SGTRPYMAPEVY 157

Query: 188 -----KQSAYDFKADIWSLGITAIELAKGEPP-----NSDLHPM 221
                ++  Y F  D WSLG++  EL K   P     N+ LH M
Sbjct: 156 GVAINERRGYGFPVDWWSLGVSLFELLKKRRPFSVHSNTSLHEM 25
>09606
          Length = 1300

 Score = 89.0 bits (219), Expect = 3e-18,   Method: Compositional matrix adjust.
 Identities = 77/282 (27%), Positives = 116/282 (41%), Gaps = 30/282 (10%)
 Frame = -3

Query: 18   ELFTKLDRIGKGSFGEVYKGIDNHTKEVVXXXXXXXXXXXXXXXXXXXXXTVLSQCDSPY 77
            E F   + +GKG    +YKG    T   V                      +      P 
Sbjct: 1115 ENFVLYEELGKGEHSIIYKGRRKGTINFVAIHCIEKCKRPEVTNTVRMTHDI----SHPN 948

Query: 78   ITRYFGSYLKSTKLWIIMEYLGGGSALDLL-KPGPLEETYIATILREILKGLDYLHSERK 136
            + ++   Y  S  LW+++E   GGS  D+L +   L ET I      ++ GL Y+HS   
Sbjct: 947  VVQFHEWYETSNHLWLVVELCTGGSLADILAQDHHLPETSIRDFGIHLVTGLHYIHSLGI 768

Query: 137  IHRDIKAANVLLSEQGDVKLADFGV-----------------AG-----QLTDTQIKRNT 174
            +  D++ + VLL   G +K ADFG+                 AG     Q  +  +K+  
Sbjct: 767  LFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEAGDQWNIQSAEEMMKQVP 588

Query: 175  FVGTPFWMAPEVIKQSAYDFKADIWSLGITAIELAKGEPP----NSDLHPMRVL---FLI 227
              G+P +MAPEV + +     +D+W+LG    E+  G PP      D+   +VL   F +
Sbjct: 587  TSGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFSGHPPFLGETYDITKDKVLNKEFPL 408

Query: 228  PKNNPPTLEGHHSKPFKEFVEACLNKDPRFRPTAKELLKHKF 269
            PK     L    S  F   +E+ L KD   R +   L+KH F
Sbjct: 407  PKVKGSRLSAKPSPEFLNLLESLLQKDSTRRLSWASLVKHAF 282
>19761
          Length = 473

 Score = 85.5 bits (210), Expect = 4e-17,   Method: Compositional matrix adjust.
 Identities = 46/145 (31%), Positives = 80/145 (55%), Gaps = 2/145 (1%)
 Frame = -3

Query: 112 LEETYIATILREILKGLDYLHSERKI--HRDIKAANVLLSEQGDVKLADFGVAGQLTDTQ 169
           L E  I   L +    L+Y+H+   +  HRD+K  N+ ++E+GDV+L D G+A +LT   
Sbjct: 432 LPERLIVCWLMQTASALNYMHTHTPVILHRDLKPQNIYVTEKGDVRLGDLGLARKLTGPA 253

Query: 170 IKRNTFVGTPFWMAPEVIKQSAYDFKADIWSLGITAIELAKGEPPNSDLHPMRVLFLIPK 229
               + VGT  +++PE++ Q  Y+ K+DIWSLG    ++  G+  + ++  M +L  +  
Sbjct: 252 DFATSQVGTIMYLSPEILSQQPYNSKSDIWSLGCVFYDIT-GKKGSDEMGVMFLLVQVMG 76

Query: 230 NNPPTLEGHHSKPFKEFVEACLNKD 254
                L  H+S+ F++ +   L KD
Sbjct: 75  GRKLPLPDHYSQEFRDTISRMLTKD 1
>30755
          Length = 1137

 Score = 81.3 bits (199), Expect = 7e-16,   Method: Compositional matrix adjust.
 Identities = 52/155 (33%), Positives = 74/155 (47%), Gaps = 7/155 (4%)
 Frame = +2

Query: 123 EILKGLDYLHSERKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWM 182
           EI+  L YLHS+  I+RD+K  N+LL + G +K+ADFG+  +         TF GTP ++
Sbjct: 56  EIISALGYLHSQGIIYRDLKLENLLLDKDGHIKVADFGLCKEDITYGRTTKTFCGTPEYL 235

Query: 183 APEVIKQSAYDFKADIWSLGITAIELAKGEPP--NSDLHPMRVLFLIPKNNPPTLEGHHS 240
           APEV+  + Y    D W  G+   E+  G  P  N D   +  L L+     P    + +
Sbjct: 236 APEVLDDNDYGRAVDWWGTGVVMYEMICGRLPFYNRDHDVLFTLILVEDVKFPR---NIT 406

Query: 241 KPFKEFVEACLNKDPRFR-----PTAKELLKHKFI 270
              K  +   L KDPR R        KE+  H F 
Sbjct: 407 DEAKSLLSGLLAKDPRNRLGGGQDDVKEIQAHPFF 511
>18484
          Length = 635

 Score = 79.0 bits (193), Expect = 3e-15,   Method: Compositional matrix adjust.
 Identities = 38/107 (35%), Positives = 58/107 (54%)
 Frame = +1

Query: 108 KPGPLEETYIATILREILKGLDYLHSERKIHRDIKAANVLLSEQGDVKLADFGVAGQLTD 167
           + G  +E   A    EI  GL +LH +  I+RD+K  NV+L  +G +K+ADFG+  +   
Sbjct: 22  QEGKFKEPVAAFYAAEIAVGLFFLHDQGIIYRDLKLDNVMLDSEGHIKIADFGMCKEGMT 201

Query: 168 TQIKRNTFVGTPFWMAPEVIKQSAYDFKADIWSLGITAIELAKGEPP 214
                 TF GTP ++APE++    Y    D W+ G+   E+  G+PP
Sbjct: 202 GDATTRTFCGTPDYIAPEIVLYQPYSKSVDWWAYGVLLFEMLAGQPP 342
>15910
          Length = 1361

 Score = 78.6 bits (192), Expect = 5e-15,   Method: Compositional matrix adjust.
 Identities = 55/187 (29%), Positives = 96/187 (51%), Gaps = 6/187 (3%)
 Frame = +2

Query: 110 GPLEETYIATILREILKGLDYLHSERKIHRDIKAANVL---LSEQGDVKLADFGVAGQLT 166
           G   E   A  + +IL G+ Y+H+   +HRD+K  N+L   +++   +KLADFG++ ++ 
Sbjct: 449 GQYTEKDAARAISDILHGVQYIHANGVVHRDLKPENLLYECMTDDSKLKLADFGLS-RII 625

Query: 167 DTQIKRNTFVGTPFWMAPEVIKQSAYDFKADIWSLGITAIELAKGEPPNSDLHPMRVLFL 226
           + +++ +T  GTP + APEV+K   Y    D+WS+G+ A  L  G  P    +   +   
Sbjct: 626 EPEVQMSTVCGTPGYCAPEVLKGDKYTPSVDMWSVGVIAYILLCGYEPFFAENEFEMYRK 805

Query: 227 IPKNNPPTLEGHH---SKPFKEFVEACLNKDPRFRPTAKELLKHKFITRYTKKTSFLTEL 283
           I K      E +    S+  K+ V   L  DP+ R TA E L+  ++     KT+ +   
Sbjct: 806 IIKGEYKFDEEYWSEISENAKDVVRKLLVIDPKKRLTATEALRLPWVKGVATKTTNMEIT 985

Query: 284 IDRYKRW 290
           +++ K +
Sbjct: 986 MNKLKEF 1006
>29581
          Length = 1278

 Score = 78.6 bits (192), Expect = 5e-15,   Method: Compositional matrix adjust.
 Identities = 47/126 (37%), Positives = 72/126 (57%), Gaps = 3/126 (2%)
 Frame = -2

Query: 91   LWIIMEYLGG--GSALDLLKPGPLEETYIATILREILKGLDYLHSERKIHRDIKAANVLL 148
            L+++MEY      S LD + P P  E+ +  I+ ++LKGL YLH    IHRD+K +N+L+
Sbjct: 1124 LFLVMEYCEQDLASLLDNM-PAPFSESQVKCIVLQLLKGLRYLHEAFIIHRDLKVSNLLM 948

Query: 149  SEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQS-AYDFKADIWSLGITAIE 207
            +++G VK+ADFG+A      Q      V T ++ APE++  S  +    D+WS G    E
Sbjct: 947  TDKGCVKIADFGLARNYGKPQKPMTPKVVTLWYRAPELLFGSKTHSTAIDMWSAGCILGE 768

Query: 208  LAKGEP 213
            L   +P
Sbjct: 767  LLGHKP 750
>03240
          Length = 1683

 Score = 78.2 bits (191), Expect = 7e-15,   Method: Compositional matrix adjust.
 Identities = 73/316 (23%), Positives = 122/316 (38%), Gaps = 63/316 (19%)
 Frame = -3

Query: 19   LFTKLDRIGKGSFGEVYKGIDNHTKEV--VXXXXXXXXXXXXXXXXXXXXXTVLSQCDSP 76
            +F K+  +G G+FGEV     N T  +  +                      +L++ D+ 
Sbjct: 1288 MFEKIKTLGVGAFGEVSLCRKNDTGMLYAMKTLRKSDVLKRNQVAHVKAERDILAEADNE 1109

Query: 77   YITRYFGSYLKSTKLWIIMEYLGGGSALDLL-----KPGPLEETYIATILREILKGLDYL 131
            ++ + + S+     L+ +M+Y+ GG  + LL        PL   Y+A    E+++ ++ +
Sbjct: 1108 WVVKLYYSFQDHNYLYFVMDYVPGGDLMGLLIRMEILDEPLARFYVA----ELVQAIESV 941

Query: 132  HSERKIHRDIKAANVLLSEQGDVKLADFGVAG-----------QLTDTQIKRN------- 173
            H    IHRDIK  N+L+   G +KL DFG+             Q   T  +++       
Sbjct: 940  HRMGFIHRDIKPDNILIDRNGHIKLTDFGLCTGFRWTHNSKYYQRDGTHARQDSMEVKCQ 761

Query: 174  --------------------------TFVGTPFWMAPEVIKQ-SAYDFKADIWSLGITAI 206
                                      + VGTP ++APEV+ +   Y    D WS+G+   
Sbjct: 760  LDEQCQCEILKPLERRRKREQRCLAHSLVGTPNYIAPEVLSRLGGYTSVCDWWSVGVILF 581

Query: 207  ELAKGEPPNSDLHPMRV---------LFLIPKNNPPTLEGHHSKPFKEFV-EACLNKDPR 256
            E+  G PP     P            +  IP+      E + S+P K+ +   C   D R
Sbjct: 580  EMLVGHPPFYANTPAETQYKVINWKDMLKIPR------ESNLSQPAKDLILRLCCGSDDR 419

Query: 257  FRPT-AKELLKHKFIT 271
                 A E+  H F  
Sbjct: 418  LGLNGAGEIKTHMFFA 371
>07291
          Length = 833

 Score = 78.2 bits (191), Expect = 7e-15,   Method: Compositional matrix adjust.
 Identities = 50/158 (31%), Positives = 74/158 (46%), Gaps = 15/158 (9%)
 Frame = +1

Query: 122 REILKGLDYLHSERKIHRDIKAANVLLSEQGDVKLADFGVAGQL-------TDTQIKRNT 174
           R+I  G+ YL   + +HR++ A N +++E G ++L+D+GV G L        D    R+ 
Sbjct: 70  RQIADGMAYLQEVKVVHRNLAARNCIVTEDGRLQLSDYGVTGSLFPQSYYTADDSPARDL 249

Query: 175 FVGTPFWMAPEVIKQSAYDFKADIWSLGITAIE-LAKGEPPNSDLHPMRVLFLIPKNNPP 233
                 WMAPE I    +  K+D+W+ G+   E L +G  P  D+    +L       P 
Sbjct: 250 VK----WMAPETIDNFHFSSKSDVWAFGVVLWELLTRGITPYPDVENSSLL-------PY 396

Query: 234 TLEGHHSK-------PFKEFVEACLNKDPRFRPTAKEL 264
             EGH  K       P  E + AC N+ P  RP   EL
Sbjct: 397 LKEGHRMKKPKQSPEPVYEMMTACWNESPEQRPDFAEL 510
>21808
          Length = 1011

 Score = 77.4 bits (189), Expect = 1e-14,   Method: Compositional matrix adjust.
 Identities = 53/195 (27%), Positives = 89/195 (45%), Gaps = 4/195 (2%)
 Frame = +1

Query: 69  VLSQCDSPYITRYFGSYLKSTKLWIIMEYLGGGSALDLL--KPGPLEETYIATILREILK 126
           ++ +   P + + +    +   ++II E +  GS L+ L  K   L+   +  I  +I  
Sbjct: 91  IMKKLRHPKLIQLYAVCTQDDPIFIITELMKNGSLLEFLQGKGRVLKLPALIDIGAQIAC 270

Query: 127 GLDYLHSERKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPF-WMAPE 185
           G+ YL S+  IHRD+ A N+L+S+   VK+ADFG+A  + + + +       P  W APE
Sbjct: 271 GMAYLESQNYIHRDLAARNILVSDNNTVKIADFGLARVIKEDEYEARVGARFPIKWTAPE 450

Query: 186 VIKQSAYDFKADIWSLGITAIE-LAKGEPPNSDLHPMRVLFLIPKNNPPTLEGHHSKPFK 244
               + +  K+D+WS GI   E +  G  P   +    VL  +             KP  
Sbjct: 451 AANYNRFTIKSDVWSFGILLTETVTYGRVPYPGMTNAEVLHQVEHGYRMPCPPGCPKPLY 630

Query: 245 EFVEACLNKDPRFRP 259
           + +  C  K+   RP
Sbjct: 631 DIMLECWRKEEMERP 675
>04852
          Length = 1462

 Score = 75.9 bits (185), Expect = 3e-14,   Method: Compositional matrix adjust.
 Identities = 62/224 (27%), Positives = 102/224 (45%), Gaps = 34/224 (15%)
 Frame = +1

Query: 78  ITRYFGSYLKSTKLWIIMEYLGGGSALDLLK-----------------PGPLEETYIATI 120
           I  + G   +   LW+I+E+   G+  D L+                 PG   +T    +
Sbjct: 136 IVNFLGCCTQGGPLWVIVEFAKNGNLRDFLESCRDGINGYGKFVSPQDPGWYTKTPGGHV 315

Query: 121 LR---------EILKGLDYLHSERKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIK 171
           +R         +I +G+++L S + IHRD+ A NVL++E+  +K+ADFG++ +  D   K
Sbjct: 316 IRRKNLLSYAFQIARGMEFLASRKCIHRDLAARNVLVTEEHVLKIADFGLS-RTGDYYKK 492

Query: 172 RNTFVGTPFWMAPEVIKQSAYDFKADIWSLGITAIELAK--GEP----PNSDLHP--MRV 223
           R+       WMAPE +    Y  K+D+WS G+   E+    G P    PN +L+   +  
Sbjct: 493 RSGGRLPVKWMAPEALFDMRYTTKSDVWSFGVVLWEIFSLGGMPYASIPNEELYSKLLDD 672

Query: 224 LFLIPKNNPPTLEGHHSKPFKEFVEACLNKDPRFRPTAKELLKH 267
            + +P+   P L    S      +E C    P  RP   +L+ H
Sbjct: 673 AYRMPR---PELA---SGNLYAIMERCWLNRPSDRPEFSQLVGH 786
>13066
          Length = 551

 Score = 72.0 bits (175), Expect = 5e-13,   Method: Compositional matrix adjust.
 Identities = 47/139 (33%), Positives = 74/139 (53%), Gaps = 5/139 (3%)
 Frame = +3

Query: 69  VLSQCDSPYITRYFGSYLKSTKLWIIMEYLGGGSALDLLKP-GPLEETYIATILREILKG 127
           +L++ D PYI +      +  K +I M +   G  L  ++  G ++E        ++   
Sbjct: 135 LLTKLDHPYIIQIHSILQRXPKNFIFMRFAERGDLLTYIQEVGFVKEKQAKIWFYQMTTA 314

Query: 128 LDYLHSERKIHRDIKAANVLLSEQGDVKLADFGVA-GQLTDT--QIKRNTFVGTPFWMAP 184
           L+YLHS    HRD+K  N+LLS   +VKLADFG A   +T++  +    T+ G+  + AP
Sbjct: 315 LNYLHSYDVAHRDLKCENILLSSHFNVKLADFGFACACITESGEKYMSRTYCGSAAYAAP 494

Query: 185 EVIKQSAYDFK-ADIWSLG 202
           E++  + Y  K AD WSLG
Sbjct: 495 EIVYGAPYAPKVADAWSLG 551
>02638
          Length = 1490

 Score = 71.6 bits (174), Expect = 5e-13,   Method: Compositional matrix adjust.
 Identities = 38/108 (35%), Positives = 65/108 (60%), Gaps = 4/108 (3%)
 Frame = +1

Query: 172 RNTFVGTPFWMAPEVIKQSAYDFKADIWSLGITAIELAKGEPP-NS-DL-HPMRVLFLIP 228
           +   +GT  +MAPEV++  +Y    D+WS+G   IE+    PP NS D+ + + ++F I 
Sbjct: 7   QGQLLGTIAFMAPEVLRGESYGRACDVWSVGCVMIEMCTCRPPWNSHDISNHLALIFKIA 186

Query: 229 KN-NPPTLEGHHSKPFKEFVEACLNKDPRFRPTAKELLKHKFITRYTK 275
            + +PP +  + S P ++ +  CL +D  FRP+AK+LL H   T+Y++
Sbjct: 187 SSVDPPPIPENMSPPVRDLMLRCLEQDSDFRPSAKDLLMHPLFTKYSQ 330
>27405
          Length = 532

 Score = 70.5 bits (171), Expect = 1e-12,   Method: Compositional matrix adjust.
 Identities = 44/125 (35%), Positives = 70/125 (56%), Gaps = 2/125 (1%)
 Frame = -3

Query: 75  SPYITRYFGSYLKSTKLWIIMEYLGGGSA-LDLLKPGPLEETYIATILREILKGLDYLHS 133
           SP+I     ++    KL  I++ + GG     L + G   E  +     E++ GL+++HS
Sbjct: 377 SPFIVCMTYAFQTPEKLCFILDLMNGGDLHYHLSQHGVFTEKEVRFYAAEVMLGLEHMHS 198

Query: 134 ERKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVI-KQSAY 192
              ++RD+K AN+LL E G V+++D G+A     ++ K +  VGT  +MAPEV+ K  AY
Sbjct: 197 RFVVYRDLKPANILLDENGHVRISDLGLACDF--SKKKPHASVGTHGYMAPEVLMKGQAY 24

Query: 193 DFKAD 197
           D  AD
Sbjct: 23  DSSAD 9
>00715
          Length = 1788

 Score = 70.5 bits (171), Expect = 1e-12,   Method: Compositional matrix adjust.
 Identities = 51/204 (25%), Positives = 92/204 (45%), Gaps = 30/204 (14%)
 Frame = +1

Query: 92  WIIMEYLGGGSALDLLKP--GPLEETYIATILREILKGLDYLHSERKIHRDIKAANVLLS 149
           W+ MEY+G  +   +L      ++ +   ++  ++ +GL YLHS   +H D+K AN LL+
Sbjct: 163 WLAMEYVGPLNLQTILNDHQQDIDSSMRLSLALQMARGLHYLHSINIVHLDLKPANCLLT 342

Query: 150 EQGDVKLADFGVAGQLTDTQIK----------------------RNTFVGTPFWMAPEVI 187
               +++ADFG   QLT T +                       +N   GT  + APE++
Sbjct: 343 RDLKLRIADFGCCHQLTPTGLDMGEREGGMAGNELELTPVQGAWKNELAGTLAYRAPELL 522

Query: 188 KQSAYDFKADIWSLGITAIELAKGEPPNSDLHPMRVLF------LIPKNNPPTLEGHHSK 241
           K      ++D++SLGIT  ++   + P   +    V++      L P   P T +     
Sbjct: 523 KGLQPSVRSDVYSLGITLWQMCTRQGPYEGVPAHAVVYQVVSKDLRPCPPPSTEDDPFEV 702

Query: 242 PFKEFVEACLNKDPRFRPTAKELL 265
            F++    C  +    RPT+ +++
Sbjct: 703 MFRDLYTQCWARRVEDRPTSLDVV 774
>26560
          Length = 398

 Score = 69.3 bits (168), Expect = 3e-12,   Method: Composition-based stats.
 Identities = 43/111 (38%), Positives = 64/111 (57%), Gaps = 2/111 (1%)
 Frame = -1

Query: 106 LLKPGPLEETYIATILREILKGLDYLHSERKIHRDIKAANVLLSEQGDVKLADFGVAGQL 165
           L + G   E  +     E++ GL+++HS   ++RD+K AN+LL E G V+++D G+A   
Sbjct: 383 LSQHGVFTEKEVRFYAAEVMLGLEHMHSRFVVYRDLKPANILLDENGHVRISDLGLA--- 213

Query: 166 TDTQIKR-NTFVGTPFWMAPEVI-KQSAYDFKADIWSLGITAIELAKGEPP 214
            D   KR +  VGT  +MAPEV+ K  +YD  AD +S G    +L KG  P
Sbjct: 212 CDFSKKRPHASVGTHGYMAPEVLMKGQSYDSSADWFSFGCMLYKLLKGHSP 60
>21079
          Length = 878

 Score = 67.4 bits (163), Expect(2) = 3e-12,   Method: Compositional matrix adjust.
 Identities = 37/127 (29%), Positives = 63/127 (49%), Gaps = 4/127 (3%)
 Frame = +1

Query: 93  IIMEYLGGGSALD--LLKPGPLEETYIATILREILKGLDYLHSERKIHRDIKAANVLL-- 148
           ++ME++G G   +  +     L E      +R+I  G+ Y+H++  +H D+K  NVL   
Sbjct: 55  LVMEFVGAGELFERVIRDDFVLTERDCVHFVRQICSGVGYMHTQSILHLDLKPENVLCVS 234

Query: 149 SEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDFKADIWSLGITAIEL 208
                +K+ DFG+A +            GTP ++APEV+     +F  D+WS+G+    L
Sbjct: 235 DNSNQIKIIDFGLA-RFYKPGDSLQVLFGTPEFIAPEVVNYDEINFTTDMWSIGVICYIL 411

Query: 209 AKGEPPN 215
             G  P+
Sbjct: 412 LSGLSPS 432

 Score = 21.6 bits (44), Expect(2) = 3e-12,   Method: Compositional matrix adjust.
 Identities = 11/50 (22%), Positives = 23/50 (46%)
 Frame = +2

Query: 239 HSKPFKEFVEACLNKDPRFRPTAKELLKHKFITRYTKKTSFLTELIDRYK 288
           HS   K+F+  C +++   R T ++  KH ++    ++        DR +
Sbjct: 509 HSDNAKDFIGNC*SREKEKRMTIEQCDKHSWLAEQDQRIRCKRLNTDRLR 658
>01756
          Length = 1858

 Score = 68.9 bits (167), Expect = 4e-12,   Method: Compositional matrix adjust.
 Identities = 56/218 (25%), Positives = 98/218 (44%), Gaps = 18/218 (8%)
 Frame = -3

Query: 14   VDPEELFTKLDRIGKGSFGEVYKGIDNHTKEVVXXXXXXXXXXXXXXXXXXXXXTVLSQ- 72
             D +  + KL +IG+G+FGEV+K     TK+VV                       + Q 
Sbjct: 1754 CDEDAKYEKLAKIGQGTFGEVFKARCKKTKQVVAMKKVLMDNEKEGFPITALREIKILQL 1575

Query: 73   ------CDSPYI--TRYFGSYLKSTKLWIIMEYL-----GGGSALDLLKPGPLEETYIAT 119
                   D   I  T+   +    +  +++ E+      G  S + ++   P     I  
Sbjct: 1574 LNHENVVDLIEICSTKATSANRYKSMFYLVFEFCEHDLAGLLSNMSVVFNLP----EIKE 1407

Query: 120  ILREILKGLDYLHSERKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTF---V 176
            ++++++ GL Y+H  + +HRD+KAAN+L+++QG +KLADFG+A   +    + N +   V
Sbjct: 1406 VMKQLMNGLYYIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRV 1227

Query: 177  GTPFWMAPE-VIKQSAYDFKADIWSLGITAIELAKGEP 213
             T ++  PE ++    Y    D W  G    E+    P
Sbjct: 1226 VTLWYRPPELLLGDRNYSTAIDQWGAGCIMAEMWTRNP 1113
>01392
          Length = 1806

 Score = 68.9 bits (167), Expect = 4e-12,   Method: Compositional matrix adjust.
 Identities = 59/208 (28%), Positives = 90/208 (43%), Gaps = 36/208 (17%)
 Frame = -1

Query: 110  GPLEETYIATILREILKGLDYLHSERKIHRDIKAANVLLSEQGD---VKLADFGVA-GQL 165
            G L E   + ++R I + LD+LHS+   HRD+K  N+L     D   VK+ DF +A G  
Sbjct: 1806 GHLCEREASLVVRHIARALDFLHSKGIAHRDLKPENILCEHLDDVVPVKICDFDLASGIS 1627

Query: 166  TDTQIKRN----TFVGTPFWMAPEVI-----KQSAYDFKADIWSLGITAIELAKGEPP-- 214
             D    +     T VG+  +MAPEV+        +YD + D+WSLGI    +  G PP  
Sbjct: 1626 CDGDGTKTPELLTPVGSAEYMAPEVVDAWVGDSFSYDKRCDLWSLGIILYIMLCGYPPFY 1447

Query: 215  -----------NSDLHPMRVLFLIPKNNPPTLEGHHSKPFKEF----------VEACLNK 253
                           H  + +           +GH+  P +E+          +   L +
Sbjct: 1446 GQCGEDCGWNRGEACHDCQDMLF-----NSIQDGHYKFPSQEWTSISSSAKDLIRHLLVR 1282

Query: 254  DPRFRPTAKELLKHKFITRYTKKTSFLT 281
            +PR R +A ++LKH +I      T   T
Sbjct: 1281 EPRKRYSAADVLKHPWICTPPAATQLAT 1198
>07940
          Length = 1336

 Score = 68.2 bits (165), Expect = 5e-12,   Method: Compositional matrix adjust.
 Identities = 35/88 (39%), Positives = 54/88 (61%), Gaps = 2/88 (2%)
 Frame = -3

Query: 123 EILKGLDYLHSERKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVG-TPF- 180
           ++ +G++YL S++ IHRD+ A NVL++E+  +K+ADFG+   L      R T  G  P  
Sbjct: 323 QVARGMEYLASKQCIHRDLAARNVLVAEEYVLKIADFGLTRNLQQFDYYRKTTDGRLPVK 144

Query: 181 WMAPEVIKQSAYDFKADIWSLGITAIEL 208
           WMAPE +    Y  K+D+WS G+   E+
Sbjct: 143 WMAPEALFDRKYTSKSDVWSYGVLLWEI 60
>09007
          Length = 1440

 Score = 68.2 bits (165), Expect = 6e-12,   Method: Compositional matrix adjust.
 Identities = 59/260 (22%), Positives = 106/260 (40%), Gaps = 20/260 (7%)
 Frame = -1

Query: 26  IGKGSFGEVYKGI---DNHTKEVVXXXXXXXXXXXXXXXXXXXXXTVLSQCDSPYITRYF 82
           +G+G FG V + I   ++  K  V                      ++   D   I R +
Sbjct: 855 LGQGHFGTVRQAIWTAESGEKVQVAVKCLSKDKIHKDGQEFLKETAIMQMLDHENIVRVY 676

Query: 83  GSYLKS-TKLWIIMEYLGGGSALDLLKPGPLEETY----IATILREILKGLDYLHSERKI 137
           G  + +   + ++ E     S L+ +K       +    +    +++  G+ YL S+R +
Sbjct: 675 GVVMDNGADIMLVTELAPMRSLLECVKEVSARVDFSVPRLCDFSQQVCDGMSYLESKRLV 496

Query: 138 HRDIKAANVLLSEQGDVKLADFGVAGQL--------TDTQIKRNTFVGTPFWMAPEVIKQ 189
           HRD+ A N+LL  +  VK++D GV+G L        +   I     V    W APE  + 
Sbjct: 495 HRDLAARNILLFSKSKVKISDVGVSGALGAGKEYYQSQQTIHLQNAVA---WCAPESFRN 325

Query: 190 SAYDFKADIWSLGITAIE-LAKGEPPNSDLHPMRVLFLIPKNNPPTLEGHHSKPFKEFVE 248
             +   +D+W+ G+   E    G  P + L+  +++  +       LE     P KE+  
Sbjct: 324 LCFSSASDVWAFGVLLWEFFTHGFQPWAGLNGQQIMEAVDAPQSQRLEQPDLCP-KEYYA 148

Query: 249 A---CLNKDPRFRPTAKELL 265
               C  ++P+ RPT  +L 
Sbjct: 147 VMLKCWEQEPQRRPTFSQLF 88
>27546
          Length = 426

 Score = 65.9 bits (159), Expect = 3e-11,   Method: Compositional matrix adjust.
 Identities = 36/101 (35%), Positives = 54/101 (53%), Gaps = 1/101 (0%)
 Frame = -1

Query: 69  VLSQCDSPYITRYFGSYLKSTKLWIIMEYLGGGSALD-LLKPGPLEETYIATILREILKG 127
           +L++ D P I +      +  K++I M Y   G  L  + K GP++E        ++ K 
Sbjct: 321 ILTRLDHPNIIQIHSILQRGPKIFIFMRYAEKGDMLSHIKKTGPIDEAQTKVWFFQMAKA 142

Query: 128 LDYLHSERKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDT 168
           L YLHS    HRD+K  N+LLS++ +VK+ADFG A    D 
Sbjct: 141 LQYLHSHDIAHRDLKCENILLSKRLNVKIADFGFARYCRDA 19
>12786
          Length = 460

 Score = 65.9 bits (159), Expect = 3e-11,   Method: Compositional matrix adjust.
 Identities = 40/125 (32%), Positives = 61/125 (48%), Gaps = 22/125 (17%)
 Frame = -3

Query: 112 LEETYIATILREILKGLDYLHSERKIHRDIKAANVLLSEQGDVKLADFGVAGQLTD--TQ 169
           L+   I    RE+L+ +  LH+E  IH D+K AN +L   G++KL DFG+A  L    T 
Sbjct: 419 LDRMMIKFYWREMLRAVKALHNEGVIHSDLKPANFMLVA-GNLKLIDFGIANTLQQDKTS 243

Query: 170 IKRNTFVGTPFWMAPEVIKQSAYD--------------------FKADIWSLGITAIELA 209
           + +++ VGTP +M+PE I  +  D                     ++D+WSLG     + 
Sbjct: 242 VLKDSRVGTPSYMSPEAIMAACDDSADDSMEEDGHRTKPKYKVGVRSDVWSLGCILYNMV 63

Query: 210 KGEPP 214
            G  P
Sbjct: 62  YGRTP 48
>00392
          Length = 668

 Score = 65.5 bits (158), Expect = 4e-11,   Method: Compositional matrix adjust.
 Identities = 46/158 (29%), Positives = 79/158 (50%), Gaps = 9/158 (5%)
 Frame = +3

Query: 69  VLSQCDSPYITRYFGSYLKSTK-----LWIIMEYLGGGSALDLLKPGPLEETYI-ATILR 122
           +L +   P I R+F  + +        + ++ E +  G+    LK        I     R
Sbjct: 90  MLKELQHPNIVRFFDYWEEHNHRNRKVIILVTELMTSGTLKTYLKRFKKPNVKILKNWCR 269

Query: 123 EILKGLDYLHSER--KIHRDIKAANVLLS-EQGDVKLADFGVAGQLTDTQIKRNTFVGTP 179
           ++LKGL +LH+     IHRD+K  N+ ++   G VK+ D G+A      Q    + +GTP
Sbjct: 270 QVLKGLYFLHTRTPPVIHRDLKCDNIFITGPTGSVKIGDLGLAT--LKNQSFAKSVIGTP 443

Query: 180 FWMAPEVIKQSAYDFKADIWSLGITAIELAKGEPPNSD 217
            +MAPE+ ++  YD   D+++ G+  +E+A  E P S+
Sbjct: 444 EFMAPEMYEEH-YDEAVDVYAFGMCMLEMASSEYPYSE 554
>14116
          Length = 1017

 Score = 65.5 bits (158), Expect = 4e-11,   Method: Compositional matrix adjust.
 Identities = 34/89 (38%), Positives = 51/89 (57%), Gaps = 3/89 (3%)
 Frame = -1

Query: 123 EILKGLDYLHSERKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQI--KRNTFVGTPF 180
           +I +G+DYL   + +HRD+ A N +L E   VK+ADFG+A  + + +     N     P 
Sbjct: 297 DIARGMDYLAGLKFVHRDLAARNCMLDEDFHVKVADFGLARDIYEKEYYSSENKKAKLPV 118

Query: 181 -WMAPEVIKQSAYDFKADIWSLGITAIEL 208
            WMA E +++  YD K D+WS G+   EL
Sbjct: 117 KWMALESLEKGNYDSKTDVWSYGVVLWEL 31
>04591
          Length = 1117

 Score = 64.3 bits (155), Expect = 8e-11,   Method: Compositional matrix adjust.
 Identities = 33/96 (34%), Positives = 59/96 (61%), Gaps = 1/96 (1%)
 Frame = -2

Query: 119 TILREILKGLDYLHSERKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGT 178
            ++ ++L GL Y+H+++ +HRDIKAAN+LL+  G +KLADFG++     ++   N  V T
Sbjct: 885 NLMSQLLNGLFYIHTKQILHRDIKAANILLTRDGVLKLADFGLSRPWVKSKRLTNRVV-T 709

Query: 179 PFWMAPE-VIKQSAYDFKADIWSLGITAIELAKGEP 213
            ++  PE ++ +  Y  + D+W +G    E+   +P
Sbjct: 708 LWYRPPELLLGEREYGPEIDMWGVGCIMAEMWSRKP 601
>21210
          Length = 518

 Score = 63.9 bits (154), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 42/119 (35%), Positives = 61/119 (51%), Gaps = 11/119 (9%)
 Frame = +3

Query: 181 WMAPEVIKQSA----YDFKADIWSLGITAIELAKGEPPNSD-LHPMRVLFLIPKNNPPTL 235
           +MAPE I   A    YD ++D+WSLGIT +ELA G  P    +     L  + +   P L
Sbjct: 18  YMAPERIDPRASSHGYDVRSDVWSLGITLMELATGRFPYRKWVSIFDQLQQVVRGVAPCL 197

Query: 236 --EGHHSKPFKEFVEACLNKDPRFRPTAKELLKHKFITRYTKK----TSFLTELIDRYK 288
             +G  S  F  FV  CL KD + RP   +LL H F+  Y ++     S++  ++D+ K
Sbjct: 198 PHDGAFSHDFVNFVNKCLTKDEKQRPKYNKLLAHPFVRLYEEQEVDVASYVCNVLDKRK 374
>21433
          Length = 590

 Score = 63.5 bits (153), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 36/97 (37%), Positives = 56/97 (57%)
 Frame = +2

Query: 118 ATILREILKGLDYLHSERKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVG 177
           A  + ++   L+Y H  + IHRDIK  N+LL  +GD+K+ADFG +     +  +R T  G
Sbjct: 176 ACYIYQLSSALEYCHYRKVIHRDIKPENLLLGLKGDLKIADFGWSVHAPSS--RRTTMCG 349

Query: 178 TPFWMAPEVIKQSAYDFKADIWSLGITAIELAKGEPP 214
           T  ++ PE+++   +D   D+WSLG+   E   G PP
Sbjct: 350 TLDYLPPEMVEGKTHDENVDLWSLGVLCYEFLVGTPP 460
>01060
          Length = 1800

 Score = 62.8 bits (151), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 63/283 (22%), Positives = 117/283 (41%), Gaps = 33/283 (11%)
 Frame = +1

Query: 20  FTKLDRIGKGSFGEVYKGIDNHT-KEVVXXXXXXXXXXXXXXXXXXXXXTVLSQCDSPYI 78
            T   +IG+G++G VYK     T +++                       +L +     I
Sbjct: 79  LTDFQKIGEGTYGVVYKCRHRATGRKLAMKKIRLRGSEDGVPSSAIREIAMLRELRHTNI 258

Query: 79  TRYFGSYLKSTKLWIIMEYLGGG--SALDLLKPGP-LEETYIATILREILKGLDYLHSER 135
                  ++  +L+++ E+L       +D    G  L+   + + + +I+ G+ + H  R
Sbjct: 259 VCLEDVIMEDERLFLVFEFLSMDLKMYIDKFPEGVVLDRRLVKSYVFQIVTGIXFCHQRR 438

Query: 136 KIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIK-QSAYDF 194
            +HRD+K  N+L++  G +K+ADFG+A             V T ++ APE++   S Y  
Sbjct: 439 IVHRDLKPQNLLINHTGAIKIADFGMARTFALPVRAYTHEVVTLWYRAPEILMGASKYST 618

Query: 195 KADIWSLGITAIELAKGEP---PNSDLHPMRVLFLI---------------PKNN---PP 233
             D+WS+G    ++    P    +S++  +  +F I               P  N   P 
Sbjct: 619 PVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIFRIIGTPTEQTWPEFHKLPAFNGMFPL 798

Query: 234 TLEGHHSKPFK-------EFVEACLNKDPRFRPTAKELLKHKF 269
             EG  S+          + +E  L  DP  R + K++L+H +
Sbjct: 799 WKEGKLSETLTDLDSLGLDLIERTLKCDPAQRISCKKMLQHAY 927
>11780
          Length = 1713

 Score = 62.4 bits (150), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 44/171 (25%), Positives = 80/171 (46%), Gaps = 6/171 (3%)
 Frame = +3

Query: 26  IGKGSFGEVYKGIDNHTKEVVXXXXXXXXXXXXXXXXXXXXXTVLSQCDSPYITRYFGSY 85
           IGKG FG+VYKG+       +                     +V++      + R  G  
Sbjct: 621 IGKGDFGDVYKGMYRGQPVAIKQLKDKDRGEQSFLQEA----SVMTSLRHDNLVRLIGVV 788

Query: 86  LKSTKLWIIMEYLGGGSALDLLKP---GPLEETYIATILREILKGLDYLHSERKIHRDIK 142
           L  T ++++ E++G G+ ++ L+      + +        +    ++YL S+R +HRD+ 
Sbjct: 789 LGET-IFLVTEFMGKGNLVEYLRSRGRSVITKKDQINFATDTCAAMEYLESKRLVHRDLA 965

Query: 143 AANVLLSEQGDVKLADFGVA--GQLTDTQIKRNTFVGTPF-WMAPEVIKQS 190
           A NVL+ + G  K++DFG+A  G  + T +K       P  W APE ++++
Sbjct: 966 ARNVLVHDDGKAKVSDFGLAKFGDFSQTSVK------FPIKWTAPEALREN 1100
>28638
          Length = 1458

 Score = 59.7 bits (143), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 29/80 (36%), Positives = 46/80 (57%), Gaps = 2/80 (2%)
 Frame = -1

Query: 137 IHRDIKAANVLLS--EQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDF 194
           IH D+K  N+LL   ++  +K+ DFG + QL     +   ++ + F+ +PEV+    YD 
Sbjct: 765 IHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQ---RIYQYIQSRFYRSPEVLLGVPYDL 595

Query: 195 KADIWSLGITAIELAKGEPP 214
             D+WSLG   +E+  GEPP
Sbjct: 594 AIDMWSLGCILVEMHTGEPP 535
>19301
          Length = 712

 Score = 58.9 bits (141), Expect = 4e-09,   Method: Compositional matrix adjust.
 Identities = 34/96 (35%), Positives = 57/96 (59%), Gaps = 3/96 (3%)
 Frame = +2

Query: 70  LSQCDSPYITRYFGSYLKSTKLWIIMEYLGGGSALDLLKPGPLEETYIATIL---REILK 126
           L + + P I  + G   ++    IIMEY   G   ++L+ G  +E   A +L   ++I  
Sbjct: 431 LRKLNHPNIISFKGVCTQAPCYCIIMEYCPYGQLYEVLRDG--KEIPPALVLDWSKQIAS 604

Query: 127 GLDYLHSERKIHRDIKAANVLLSEQGDVKLADFGVA 162
           G++YLHS + IHRD+K+ NVL+++   VK++DFG +
Sbjct: 605 GMNYLHSHKIIHRDLKSPNVLVAKNDVVKISDFGTS 712
>26711
          Length = 405

 Score = 57.4 bits (137), Expect = 1e-08,   Method: Composition-based stats.
 Identities = 34/101 (33%), Positives = 59/101 (58%), Gaps = 6/101 (5%)
 Frame = -2

Query: 120 ILREILKGLDYLHSERKIHRDIKAANVLLSEQGD----VKLADFGVAGQLTDTQIKRNTF 175
           +++++L  L ++H++  +H D+K +N+LLS  GD    V+L DFG+A +L   Q    TF
Sbjct: 401 VVKQVLDILQHVHAQGVVHMDLKPSNLLLS--GDKLDSVQLIDFGLARKLYPPQ---ETF 237

Query: 176 V--GTPFWMAPEVIKQSAYDFKADIWSLGITAIELAKGEPP 214
           +  GTP + +PE +        +D+W +G+ A  L  G+ P
Sbjct: 236 LNHGTPGFTSPEALDVKPISTASDVWGVGVLAYILLSGQSP 114
>07836
          Length = 1478

 Score = 55.5 bits (132), Expect = 4e-08,   Method: Compositional matrix adjust.
 Identities = 40/140 (28%), Positives = 71/140 (50%), Gaps = 18/140 (12%)
 Frame = -1

Query: 89   TKLWIIMEYLGGGSALDLLKPGPLEETYIATILREILKGLDYLHSE--------RKIHRD 140
            T+L++I +Y   GS  D L    L+ + +  +    + GL +LH E           HRD
Sbjct: 1334 TQLFLITDYHENGSLHDYLLSRVLDSSEMLALAHSAICGLAHLHIEIFGTRGKPAIAHRD 1155

Query: 141  IKAANVLLSEQGDVKLADFGVA----GQLTDTQIKRNTFVGTPFWMAPEVIKQ--SAYDF 194
            IK+ N+L+ + G   +AD G+A     +  +  +  N   GT  +MAPEV++   +  +F
Sbjct: 1154 IKSKNILVKKNGTCCIADLGLAVRYISESNEVDVAPNPRQGTKRYMAPEVLEMLLNVKNF 975

Query: 195  ----KADIWSLGITAIELAK 210
                +AD+++ G+   E+A+
Sbjct: 974  DAFKQADMYAFGLVMWEIAR 915
>17975
          Length = 449

 Score = 55.5 bits (132), Expect = 5e-08,   Method: Compositional matrix adjust.
 Identities = 33/93 (35%), Positives = 48/93 (51%), Gaps = 3/93 (3%)
 Frame = +3

Query: 76  PYITRYFGSYLKSTKLWIIMEYLGGGSALDLL--KPGPLEETYIATILREILKGLDYLHS 133
           P + R +      TKL++I+E   GG   D +    G LEE       R+I++ + Y H 
Sbjct: 144 PNVVRLYEVIDTQTKLYLILELGDGGDMYDYIMRHSGGLEEKLAKRYFRQIVEAISYCHK 323

Query: 134 ERKIHRDIKAANVLLSEQ-GDVKLADFGVAGQL 165
              +HRD+K  NV+  E+ G VKL DFG +  L
Sbjct: 324 LHVVHRDLKPENVVFFEKPGLVKLTDFGFSTCL 422
>03508
          Length = 1463

 Score = 55.1 bits (131), Expect = 5e-08,   Method: Compositional matrix adjust.
 Identities = 33/100 (33%), Positives = 57/100 (57%), Gaps = 3/100 (3%)
 Frame = +1

Query: 117 IATILREILKGLDYLHSERKIHRDIKAANVLLS-EQGDVKLADFGVAGQLTDTQIKRNTF 175
           I   L E++K LD+ HS   +HRD+K  NV++  E   ++L D+G+A +     ++ N  
Sbjct: 877 IRFYLYELMKALDFCHSMGIMHRDVKPHNVMIDHENKKLRLIDWGLA-EFYHPGMEYNVR 1053

Query: 176 VGTPFWMAPE-VIKQSAYDFKADIWSLG-ITAIELAKGEP 213
           V + ++  PE ++    YD+  D+WSLG + A  + + EP
Sbjct: 1054VASRYFKGPELLLDYQMYDYSLDMWSLGCMFASMIFRKEP 1173
>11185
          Length = 473

 Score = 55.1 bits (131), Expect = 5e-08,   Method: Compositional matrix adjust.
 Identities = 44/168 (26%), Positives = 68/168 (40%), Gaps = 22/168 (13%)
 Frame = +1

Query: 124 ILKGLDYLHSERKIHRDIKAANVLLSEQGDVKLADFGV-----------------AG--- 163
           ++ GL Y+HS   +  D++ + VLL   G +K ADFG+                 AG   
Sbjct: 28  LVTGLHYIHSLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEAGDQW 207

Query: 164 --QLTDTQIKRNTFVGTPFWMAPEVIKQSAYDFKADIWSLGITAIELAKGEPPNSDLHPM 221
             Q  +  +K+    G+P +MAPEV + +     +D+W+LG    E+  G          
Sbjct: 208 NIQSAEEMMKQVPTSGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFSGS--------- 360

Query: 222 RVLFLIPKNNPPTLEGHHSKPFKEFVEACLNKDPRFRPTAKELLKHKF 269
                        L    S  F   +E+ L KD   R +   L+KH F
Sbjct: 361 ------------RLSAKPSPEFLNLLESLLQKDSTRRLSWASLVKHAF 468
>18996
          Length = 491

 Score = 54.3 bits (129), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 42/142 (29%), Positives = 71/142 (50%), Gaps = 12/142 (8%)
 Frame = +2

Query: 137 IHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGT-----PF-WMAPEVIKQS 190
           IHRD+ A N+L+ ++  VK++DFG+A Q  +       + G      P  W +PE I+  
Sbjct: 2   IHRDLAARNILV-DRSCVKISDFGLA-QFANAD---GYYYGISQRDIPIKWYSPEAIETC 166

Query: 191 AYDFKADIWSLGITAIEL-AKGEPPN----SDLHPMRVLFLIPKNNP-PTLEGHHSKPFK 244
            +   +D+WS G+T  E+ ++GE PN     DL     L  + K    P  E      + 
Sbjct: 167 KFSSYSDVWSYGVTLFEMFSRGEIPNLLPGHDLTQEEFLNRLRKGERLPKPELCSDFVYS 346

Query: 245 EFVEACLNKDPRFRPTAKELLK 266
           E +  C ++ P+ RPT  ++++
Sbjct: 347 ELMRPCWHEMPKSRPTFHQIIQ 412
>04138
          Length = 800

 Score = 53.9 bits (128), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 31/90 (34%), Positives = 49/90 (54%), Gaps = 4/90 (4%)
 Frame = +1

Query: 128 LDYLHSERKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTF---VGTPFWMAP 184
           L Y+H  + +HRD+KAAN+L+++QG +KLADFG+A   +    + N +   V T ++  P
Sbjct: 52  LYYIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRVVTLWYRPP 231

Query: 185 E-VIKQSAYDFKADIWSLGITAIELAKGEP 213
           E ++    Y    D W  G    E+    P
Sbjct: 232 ELLLGDRNYSTAIDQWGAGCIMAEMWTRNP 321
>17300
          Length = 480

 Score = 53.9 bits (128), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 37/124 (29%), Positives = 58/124 (46%), Gaps = 5/124 (4%)
 Frame = +1

Query: 124 ILKGLDYLHSERKIHRDIKAANVLLSEQGDVKLADFGVAGQL-TDTQIKRNTFVGTPF-- 180
           I  G+  L     +HRD+ A N+L++E    K+ADFG++ ++ +DT     T  G     
Sbjct: 1   ISSGMGXLADMGYVHRDLAARNILVNEILVCKVADFGLSREIESDTTEGAYTTKGGKIPV 180

Query: 181 -WMAPEVIKQSAYDFKADIWSLGITAIE-LAKGEPPNSDLHPMRVLFLIPKNNPPTLEGH 238
            W APE I    +   +D+WS G+   E ++ GE P  +     V+  + K     L G 
Sbjct: 181 RWTAPEAIAYRKFTSASDVWSFGVVMWEVMSYGERPYWNWSNQDVIKAVEKGYRLPLHGL 360

Query: 239 HSKP 242
              P
Sbjct: 361 SGSP 372
>20825
          Length = 662

 Score = 53.1 bits (126), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 26/71 (36%), Positives = 42/71 (59%), Gaps = 7/71 (9%)
 Frame = +3

Query: 355 SQCLSTLVRPVFGELKEKHKQSGGSVG-------ALEELENAFSLAEESCPGISDKLMVH 407
           S  L  +V+P+   L+E +++    +G       A++EL NAF LAE+SCPG++D L+  
Sbjct: 291 SSSLGQVVKPILSTLREDYREEYRRIGKPIPLTQAIDELRNAFDLAEQSCPGLTDSLLSG 470

Query: 408 LVERVQRFSHS 418
           +V R+   S S
Sbjct: 471 IVTRLVGSSRS 503
>14477
          Length = 493

 Score = 52.4 bits (124), Expect = 4e-07,   Method: Compositional matrix adjust.
 Identities = 37/155 (23%), Positives = 68/155 (43%), Gaps = 13/155 (8%)
 Frame = -1

Query: 25  RIGKGSFGEVYKGI---DNHTKEVVXXXXXXXXXXXXXXXXXXXXXTVLSQCDSPYITRY 81
           ++G G+FG V KG+   D+    V                       V+ + D  +I R 
Sbjct: 469 KLGAGNFGSVMKGVCRLDDREIPVAIKVLKNADLDPSVQSELIKEAEVMKKMDHMHIVRL 290

Query: 82  FGSYLKSTKLWIIMEYLGGGSALDLLKPGPLEETY----------IATILREILKGLDYL 131
            G     T + +          L+L K GPL +            I  ++ ++ +G++YL
Sbjct: 289 IGLCEGETMMLV----------LELAKLGPLNKFLPKNKHLPLWNILELMWQVSQGMEYL 140

Query: 132 HSERKIHRDIKAANVLLSEQGDVKLADFGVAGQLT 166
            + + +HRD+ A N+LL ++   K++DFG++  L+
Sbjct: 139 EANKFVHRDLAARNILLCDEHFAKISDFGMSKTLS 35
>25019
          Length = 730

 Score = 51.2 bits (121), Expect = 7e-07,   Method: Compositional matrix adjust.
 Identities = 27/61 (44%), Positives = 40/61 (65%), Gaps = 1/61 (1%)
 Frame = +3

Query: 143 AANVLLSEQGDVKLADFGVAGQ-LTDTQIKRNTFVGTPFWMAPEVIKQSAYDFKADIWSL 201
           A NVLL + G VKL DFG+  + +T T++  +TF GT  +MAPE++ ++ +    D WSL
Sbjct: 258 AENVLLDKDGHVKLTDFGLCKEAITGTRVT-HTFCGTIEYMAPEILTRTGHGKAVDWWSL 434

Query: 202 G 202
           G
Sbjct: 435 G 437
>01966
          Length = 1735

 Score = 51.2 bits (121), Expect = 8e-07,   Method: Compositional matrix adjust.
 Identities = 28/105 (26%), Positives = 57/105 (54%), Gaps = 3/105 (2%)
 Frame = -1

Query: 86   LKSTKLWIIMEYLGGG--SALDLLKPGP-LEETYIATILREILKGLDYLHSERKIHRDIK 142
            ++  +L+++ E+L       +D    G  L+   + + + +I+ G+++ H  R +HRD+K
Sbjct: 1504 MEDERLFLVFEFLSMDLKMYIDKFPEGVVLDRRLVKSYVFQIVTGINFCHQRRIVHRDLK 1325

Query: 143  AANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVI 187
              N+L++  G +K+ADFG+A             V T ++ APE++
Sbjct: 1324 PQNLLINHTGAIKIADFGMARTFALPVRAYTHEVVTLWYRAPEIL 1190
>12672
          Length = 773

 Score = 50.8 bits (120), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 31/99 (31%), Positives = 50/99 (50%), Gaps = 7/99 (7%)
 Frame = +3

Query: 120 ILREILKGLDYLHSERKIHRDIKAANVLLSEQGDVKLADFGV-----AGQLTDTQIKRNT 174
           I++    G+ YL+    +HRDIK AN+LL  +   K+ DF       +G+    Q   + 
Sbjct: 6   IVKGTASGIQYLNDNGHVHRDIKTANILLDSEYTAKVGDFATVVSAPSGEGKTVQ-NASV 182

Query: 175 FVGTPFWMAPEVIKQSAYDF--KADIWSLGITAIELAKG 211
            +GT  ++APE I    +D   K D +S G+  +E+  G
Sbjct: 183 VIGTAAYLAPEAIH---FDVSTKLDSYSFGVVLLEVITG 290
>20640
          Length = 1492

 Score = 50.1 bits (118), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 37/141 (26%), Positives = 60/141 (42%), Gaps = 11/141 (7%)
 Frame = +1

Query: 137 IHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNT-FVGTPF-WMAPEVIKQSAYDF 194
           +HRD+   N L+     VK++DFG+A  +      R +     P  WM  E I  + +  
Sbjct: 10  VHRDLATRNCLVGHDLVVKISDFGLARSVHSVDYYRGSEHDAIPIRWMPLEAILYNKFST 189

Query: 195 KADIWSLGITAIELAKG--EPPNSDLHPMRVLFL-------IPKNNPPTLEGHHSKPFKE 245
           ++D+WS G+   E+     +P     H   V F+        P+  PP        P  E
Sbjct: 190 QSDVWSFGVVLWEIFAFALQPYYGLTHEEVVRFVKEGKVLACPERTPP--------PMYE 345

Query: 246 FVEACLNKDPRFRPTAKELLK 266
            ++ C ++ P  RP+   L K
Sbjct: 346 LMKQCWHRRPATRPSFHTLHK 408
>17253
          Length = 483

 Score = 49.3 bits (116), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 26/105 (24%), Positives = 51/105 (48%), Gaps = 13/105 (12%)
 Frame = -1

Query: 76  PYITRYFGSYLKSTKLWIIMEYLGGGSALDLL-KPGPLEETYIATILRE----------- 123
           P +  + G    S    I+ME+   G  L  L K  P    ++ +   +           
Sbjct: 366 PNVVSFMGCCTMSDPALILMEFCCHGDLLSFLRKRRPDRTVFLTSTANDLTARDFFSFAL 187

Query: 124 -ILKGLDYLHSERKIHRDIKAANVLLSEQGDVKLADFGVAGQLTD 167
            + +G+ ++ + + +HRD+ A NVL+SE+   K++DFG++ ++ D
Sbjct: 186 HVARGMAHVANNKIVHRDVAARNVLISERNVCKVSDFGLSRRVGD 52
>07833
          Length = 1504

 Score = 47.8 bits (112), Expect = 8e-06,   Method: Compositional matrix adjust.
 Identities = 38/149 (25%), Positives = 68/149 (45%), Gaps = 12/149 (8%)
 Frame = -3

Query: 123  EILKGLDYLHSERKIHRD--IKAANVLLSEQ--GDVKLADFGVAGQLTDTQIKRNTFVGT 178
            +I +G+++LHS      +  + + +V++ E     + +AD+  +             V +
Sbjct: 1289 DIARGMEFLHSMEPTIPNFLLTSKHVMIDEDLTARINMADYCFS-------FHEKGKVYS 1131

Query: 179  PFWMAPEVIKQSAYDFK---ADIWSLGITAIELAKGEPPNSDLHPMRVLFLIPKNN---- 231
            P WMAPE +++   D     AD+WS  I   EL   E P ++L  M V   +        
Sbjct: 1130 PAWMAPEALQRRPDDINTRAADMWSFAILMWELETREVPFAELSSMEVGMKVALEGLRIS 951

Query: 232  -PPTLEGHHSKPFKEFVEACLNKDPRFRP 259
             PP +  H S+     ++ C+N++P  RP
Sbjct: 950  IPPGISLHMSR----LIKICMNEEPGKRP 876
>14326
          Length = 700

 Score = 47.4 bits (111), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 25/71 (35%), Positives = 39/71 (54%), Gaps = 7/71 (9%)
 Frame = -2

Query: 355 SQCLSTLVRPVFGELKEKHKQSGGSVG-------ALEELENAFSLAEESCPGISDKLMVH 407
           S CL ++V P+   L+E +++    +G       AL+EL NAF L E SC G++  L+  
Sbjct: 411 SPCLDSVVHPILRTLREDYQEEYRRIGRPLPLTEALDELGNAFDLVERSCGGVTASLLTG 232

Query: 408 LVERVQRFSHS 418
           +V R+   S S
Sbjct: 231 IVTRLASASRS 199
>28411
          Length = 529

 Score = 46.6 bits (109), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 31/100 (31%), Positives = 54/100 (54%), Gaps = 16/100 (16%)
 Frame = +2

Query: 338 ALHSSQK--PAEPIKRQPRSQCLSTLVR-------PVFGELKEKHKQSGGSVG------- 381
           A+ ++Q+  P+ P  +Q  S C  +L++       P    L+E +++    +G       
Sbjct: 86  AVQTNQRTGPSSPPGQQQHSAC--SLLQSGPSGQNPFLSTLREDYREEYRRIGKPIPLTQ 259

Query: 382 ALEELENAFSLAEESCPGISDKLMVHLVERVQRFSHSRNH 421
           A++EL NAF LAE+SCPG++D L+  +V R+   S S + 
Sbjct: 260 AIDELRNAFDLAEQSCPGLTDSLLSGIVTRLVGSSRSASQ 379
>28157
          Length = 400

 Score = 46.2 bits (108), Expect = 3e-05,   Method: Composition-based stats.
 Identities = 34/101 (33%), Positives = 55/101 (54%), Gaps = 8/101 (7%)
 Frame = +3

Query: 70  LSQCDSPYITRYFGSYLKSTKLWIIMEYLGGGSALDLLK-PGPLEETYIATILREILK-- 126
           LS+   P I   +G+  +   + ++MEY  GGS  ++L   GP  +   A  +  +L+  
Sbjct: 72  LSRVSHPNIVCLYGA-CRDHPVCLVMEYAEGGSLYNVLHGSGPQPQYTAAHAMNWLLQCA 248

Query: 127 -GLDYLHSERK---IHRDIKAANVLLSEQG-DVKLADFGVA 162
            G++YLH  +    IHRD+K  N+LL + G  +K+ DFG A
Sbjct: 249 LGVEYLHGMKPKALIHRDLKPPNLLLIQCGTKLKICDFGTA 371
>18663
          Length = 600

 Score = 43.9 bits (102), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 17/42 (40%), Positives = 26/42 (61%)
 Frame = +2

Query: 173 NTFVGTPFWMAPEVIKQSAYDFKADIWSLGITAIELAKGEPP 214
           +TF GTP ++APE+++   Y F  D W+LG+   E+  G  P
Sbjct: 2   STFCGTPNYIAPEILRGEDYGFSVDWWALGVLLYEMLAGRSP 127
>16708
          Length = 1397

 Score = 43.5 bits (101), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 59/268 (22%), Positives = 97/268 (36%), Gaps = 32/268 (11%)
 Frame = -1

Query: 23   LDRIGKGSFGEVYKG--IDNHTKEVVXXXXXXXXXXXXXXXXXXXXXTVLSQCDSPYITR 80
            L  +GKG FG+VY+   +  H K  +                              Y+ +
Sbjct: 1388 LQVLGKGVFGKVYEARLLSTHEKAALKTSILCHHSLDEVEALGRIEGGF-------YLAQ 1230

Query: 81   YFGSYLKST---KLWIIMEYLGGGSALDLL-----KPGPL---EETYIATILREILKGLD 129
             FG+++      K+ I++ +   G   ++      K  P+       +  I  + +  L+
Sbjct: 1229 MFGAWVTCLPFPKMNILLHFYEMGPLCNVYAHYKNKEMPIRWSNPAMVCCIAGQXVCALE 1050

Query: 130  YLHSERKIHRDIKAANVLLSEQGDVKLADFGVAGQL-------TDTQI-----KRNTFVG 177
            ++H    +H D+KA NVL+   G+ KL D+G+A QL       T+T       KR  +  
Sbjct: 1049 HIHELGVVHMDVKADNVLVDAHGNCKLTDYGIA-QLYKVYPAPTETHSSGCTNKRTFYTR 873

Query: 178  TPFWMAP-EVIKQSAYDFKADIWSLGITAIELAKGEPPNSDLHPMRVLFLIPKNNPPTLE 236
             P  M P E   +       D + LG     L              VL  +  + PP L 
Sbjct: 872  PPATMTPSERFSEEGDGIGTDYFRLGQMLWTLTGA-----------VLLHVWVSRPPKLP 726

Query: 237  GHHSKP------FKEFVEACLNKDPRFR 258
                 P        +F+E   + DP  R
Sbjct: 725  DWCRTPESELSGMSDFIEKLCHGDPNMR 642
>29590
          Length = 320

 Score = 36.6 bits (83), Expect(2) = 4e-04,   Method: Composition-based stats.
 Identities = 18/46 (39%), Positives = 26/46 (56%)
 Frame = +3

Query: 158 DFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDFKADIWSLGI 203
           D G A  LT+T       +GTP ++APEV+       + D+WSLG+
Sbjct: 6   DLGFAC-LTNTGEDIRDIIGTPDYVAPEVLDYEPLSIQTDMWSLGV 140

 Score = 25.0 bits (53), Expect(2) = 4e-04,   Method: Composition-based stats.
 Identities = 13/29 (44%), Positives = 16/29 (55%)
 Frame = +2

Query: 232 PPTLEGHHSKPFKEFVEACLNKDPRFRPT 260
           P  L  H S   K+F++  L KDPR R T
Sbjct: 233 PDDLFSHISPHAKDFIKKLLVKDPRHRMT 319
>06358
          Length = 1517

 Score = 42.0 bits (97), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 43/170 (25%), Positives = 79/170 (46%), Gaps = 21/170 (12%)
 Frame = +3

Query: 121 LREILKGLDYLHSERKI-HRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTP 179
           L ++ + L +LH++ K+ HR++    ++L++ G  KLA +    + +D Q   +T    P
Sbjct: 378 LLQVTEALGFLHNDAKMMHRNVCPEAIMLTKLGSWKLAGYEFCVRSSDPQ---STDPSYP 548

Query: 180 FW----------------MAPEVIKQSAYDFKADIWSLGITAIEL-AKGEP---PNSDLH 219
           F+                MAPE +        +D++SLG+    + AKG+P    N +L 
Sbjct: 549 FYEWRSDIAPVTQPHLDFMAPEYVLTMQCGTGSDMFSLGLLVYSVFAKGKPLFECNGELS 728

Query: 220 PMRVLFLIPKNNPPTLEGHHSKPFKEFVEACLNKDPRFRPTAKELLKHKF 269
             +      ++   +L G   +  ++ V+  LN +P  RP A +L K  F
Sbjct: 729 AFKSNAEELRHMRVSLLGVVPEDLRDHVKLLLNIEPAVRPDAAQLSKVPF 878
>17516
          Length = 453

 Score = 42.0 bits (97), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 21/41 (51%), Positives = 26/41 (63%), Gaps = 1/41 (2%)
 Frame = -3

Query: 173 NTFVGTPFWMAPEVIKQSA-YDFKADIWSLGITAIELAKGE 212
            T  GTP +MAPEV+ Q   YD KAD++SL I   EL  G+
Sbjct: 445 GTLAGTPVYMAPEVLLQKGQYDMKADVYSLAIILWELWYGQ 323
>31489
          Length = 329

 Score = 40.8 bits (94), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 20/65 (30%), Positives = 34/65 (52%)
 Frame = +3

Query: 83  GSYLKSTKLWIIMEYLGGGSALDLLKPGPLEETYIATILREILKGLDYLHSERKIHRDIK 142
            SY     + ++ + +       +    PL E +I   L +IL+GL Y+HS   +HRD+K
Sbjct: 69  DSYHDFKDIHVVFDLMESDLHRIIYSDQPLTEEHIRYFLYQILRGLKYIHSANVVHRDLK 248

Query: 143 AANVL 147
            +N+L
Sbjct: 249 PSNLL 263
>20152
          Length = 445

 Score = 39.7 bits (91), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 29/103 (28%), Positives = 48/103 (46%), Gaps = 6/103 (5%)
 Frame = +1

Query: 184 PEVIKQSAYDFKA-DIWSLGITAIELAKGEPPNSDLHPMRVLFLIPKNN---PPTLEGHH 239
           PE++   +YD  A D+WSLG+    L  GE P  + +    L +I       PP    H 
Sbjct: 1   PEILLGDSYDAPAVDVWSLGVILYMLVVGEAPFQEANDSETLTMIMDCRYQIPP----HI 168

Query: 240 SKPFKEFVEACLNKDPRFRPTAKELLKHKFIT--RYTKKTSFL 280
           S   ++ +E  L ++P  R +   +L H ++     T  T++L
Sbjct: 169 SHKCQDLIEKMLQREPVDRASLPHILAHPWLNDGDLTPTTAYL 297
>38560
          Length = 479

 Score = 39.7 bits (91), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 36/120 (30%), Positives = 52/120 (43%), Gaps = 3/120 (2%)
 Frame = -3

Query: 173 NTFVGTPFWMAPEVIKQSAY-DFKADIWSLGITAIELAKGEPPNSDLHPMRVLFLIPKNN 231
            T  G+P + APE+I    Y   +ADIWS+G+    L  G  P  D    +   L  KN 
Sbjct: 411 TTCCGSPAYAAPELISGLEYLGSEADIWSMGVLLYALLCGYLPFDD---EKXSHL*QKNQ 241

Query: 232 PPTLEGHH--SKPFKEFVEACLNKDPRFRPTAKELLKHKFITRYTKKTSFLTELIDRYKR 289
               E     S+   + +E  L  DP  R T + LL H ++    +  +   E   +YKR
Sbjct: 240 KRKDEVPEWLSEDTTKLLEGMLQTDPSHRITIRRLLDHHWL---NQGFNVPVEWASKYKR 70
>13840
          Length = 446

 Score = 38.9 bits (89), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 34/128 (26%), Positives = 57/128 (44%), Gaps = 9/128 (7%)
 Frame = -1

Query: 23  LDRIGKGSFGEVYKGIDNHTKEVVXXXXXXXXXXXXXXXXXXXXXTVLSQCDS-PYITRY 81
           +  IG+G++G V K     T  V+                      V+ + ++ P+I ++
Sbjct: 380 MGEIGRGNYGTVNKMRHKITSTVMAVKRIRSTVEEREQKQLLMDLDVVMRSNNCPFIVQF 201

Query: 82  FGSYLKSTKLWIIMEYLGGGSALDLLKP---GPLEETYIATILREI----LKGLDYLHSE 134
           +G+  K    WI ME +   ++LD       G ++ +    IL +I    LK L+YL  E
Sbjct: 200 YGALFKEGDCWICMELM--ETSLDKFYKFVYGEMQSSIPENILGKITVATLKALNYLKEE 27

Query: 135 -RKIHRDI 141
            R IHRD+
Sbjct: 26  LRIIHRDV 3
>00486
          Length = 797

 Score = 38.9 bits (89), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 16/41 (39%), Positives = 24/41 (58%)
 Frame = -2

Query: 174 TFVGTPFWMAPEVIKQSAYDFKADIWSLGITAIELAKGEPP 214
           TF GT  +MAPE++ ++ +    D WSLG    ++  G PP
Sbjct: 781 TFCGTIEYMAPEILTRTGHGKAVDWWSLGALMYDMLTGSPP 659
>26009
          Length = 886

 Score = 38.1 bits (87), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 12/30 (40%), Positives = 25/30 (83%)
 Frame = +3

Query: 119 TILREILKGLDYLHSERKIHRDIKAANVLL 148
           +++++++  LD++HS++ +HRDIK  NVL+
Sbjct: 723 SVMKQLVSALDFMHSKQLVHRDIKPENVLI 812
>22005
          Length = 873

 Score = 36.2 bits (82), Expect = 0.025,   Method: Compositional matrix adjust.
 Identities = 26/91 (28%), Positives = 44/91 (48%), Gaps = 2/91 (2%)
 Frame = +1

Query: 120 ILREILKGLDYLHSERKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFV-GT 178
           I ++I  G+ YL  +  +HRD+ A   + S      ++DFG+A  +      R +     
Sbjct: 457 ISQQISAGMAYLAQKDYVHRDL-ATRTVXSRTT*S*ISDFGLARSVHSVDYYRGSEQDAI 633

Query: 179 PF-WMAPEVIKQSAYDFKADIWSLGITAIEL 208
           P  WM  E I  S +  ++D+WS G+   E+
Sbjct: 634 PIRWMPLEAILYSKFSTQSDVWSFGVVLWEI 726
>32691
          Length = 295

 Score = 36.2 bits (82), Expect = 0.028,   Method: Composition-based stats.
 Identities = 16/33 (48%), Positives = 21/33 (63%)
 Frame = +1

Query: 240 SKPFKEFVEACLNKDPRFRPTAKELLKHKFITR 272
           S  F +FV  CL K+P  R TA +LL+H FI +
Sbjct: 88  STEFIDFVSKCLVKNPENRATAVDLLQHDFIKK 186
>17637
          Length = 447

 Score = 35.4 bits (80), Expect = 0.048,   Method: Compositional matrix adjust.
 Identities = 19/72 (26%), Positives = 38/72 (52%), Gaps = 12/72 (16%)
 Frame = +1

Query: 164 QLTDTQIKRNTFVGT----------PF-WMAPEVIKQSAYDFKADIWSLGITAIELAK-G 211
           +LTD+ + R+ F G           P  W++ E +++S Y+  +D+WS G+   E+   G
Sbjct: 31  KLTDSALSRDLFSGDYNCLGDGEYRPIKWLSLEALQKSHYNEGSDVWSFGVLMWEMCTLG 210

Query: 212 EPPNSDLHPMRV 223
           + P +++ P  +
Sbjct: 211 KLPYAEIDPYEM 246
>18401
          Length = 463

 Score = 35.0 bits (79), Expect = 0.054,   Method: Compositional matrix adjust.
 Identities = 15/39 (38%), Positives = 21/39 (53%)
 Frame = -3

Query: 173 NTFVGTPFWMAPEVIKQSAYDFKADIWSLGITAIELAKG 211
           +T V T  + APEVI +  +    D+WS+G    EL  G
Sbjct: 458 STIVSTRHYRAPEVILELGWSHPCDVWSVGCIMFELYTG 342
>01106
          Length = 878

 Score = 35.0 bits (79), Expect = 0.057,   Method: Compositional matrix adjust.
 Identities = 15/34 (44%), Positives = 25/34 (73%), Gaps = 1/34 (2%)
 Frame = +3

Query: 117 IATILREILKGLDYLHSE-RKIHRDIKAANVLLS 149
           +  I+R++L+GL Y+H++ R IH DIK  N+L+ 
Sbjct: 651 VKLIIRQVLEGLSYMHAKCRIIHTDIKPENILIC 752
>32957
          Length = 645

 Score = 34.7 bits (78), Expect = 0.081,   Method: Compositional matrix adjust.
 Identities = 17/38 (44%), Positives = 22/38 (57%)
 Frame = +3

Query: 171 KRNTFVGTPFWMAPEVIKQSAYDFKADIWSLGITAIEL 208
           +  TF GT  +MAPEV ++  Y  + D W LGI   EL
Sbjct: 33  RTRTFCGTREYMAPEVHERKEYGKEVDWWGLGILLHEL 146
>37063
          Length = 455

 Score = 34.3 bits (77), Expect = 0.10,   Method: Compositional matrix adjust.
 Identities = 27/76 (35%), Positives = 40/76 (52%), Gaps = 13/76 (17%)
 Frame = -2

Query: 141 IKAANVL---LSEQGDVKLADFGVA-GQLTDTQIKRN----TFVGTPFWMAPEVI----- 187
           +K  N+L   L E   +K+ DF +A G   D    +     T VG+  +MAPEV+     
Sbjct: 454 LKPENILCEHLDEVVPLKICDFDLASGINCDGDGTKTPELLTPVGSAEYMAPEVVDAWVG 275

Query: 188 KQSAYDFKADIWSLGI 203
           +  +YD + D+WSLGI
Sbjct: 274 ESFSYDKRCDMWSLGI 227
>18481
          Length = 437

 Score = 32.7 bits (73), Expect = 0.32,   Method: Compositional matrix adjust.
 Identities = 25/81 (30%), Positives = 42/81 (51%), Gaps = 14/81 (17%)
 Frame = -1

Query: 103 ALDLLKPGPLEETYIA--------TILR---EILKGLDYLHSERKIHRDIKAANVLLS-- 149
            ++LL P  LEE ++         TIL    ++L  L+++H +  IHRD+K  N L+   
Sbjct: 263 VMELLGPS-LEELFVICKRRFTLKTILMVSDQLLSRLEFIHQKCFIHRDLKPDNFLMGLG 87

Query: 150 -EQGDVKLADFGVAGQLTDTQ 169
                + + DFG++ +  DTQ
Sbjct: 86  RHCHRLYIIDFGLSKRYKDTQ 24
>13305
          Length = 549

 Score = 32.3 bits (72), Expect = 0.34,   Method: Compositional matrix adjust.
 Identities = 25/89 (28%), Positives = 40/89 (44%), Gaps = 5/89 (5%)
 Frame = +2

Query: 181 WMAPEVIKQSAYDFKADIWSLGITAIEL-AKGEPPNSDLHPMRVLFLIPKNN----PPTL 235
           WMA E +  + Y  ++D+WS G+   E+   G  P S     + LF   K+      P L
Sbjct: 23  WMAVESLFNNTYTTQSDVWSFGVVLWEIFTLGGTPYSSTDTQQ-LFAFLKDGYRLKRPKL 199

Query: 236 EGHHSKPFKEFVEACLNKDPRFRPTAKEL 264
              ++      +  C N++ + RPT  EL
Sbjct: 200 CDQNTYA---MMLQCWNENAQRRPTFPEL 277
>00394
          Length = 548

 Score = 31.2 bits (69), Expect = 0.76,   Method: Compositional matrix adjust.
 Identities = 14/25 (56%), Positives = 18/25 (72%), Gaps = 1/25 (4%)
 Frame = -2

Query: 16  PEELFTKLDR-IGKGSFGEVYKGID 39
           P+  F K D+ IG+GSF  VYKG+D
Sbjct: 307 PDNRFLKFDKEIGRGSFKTVYKGLD 233
>32000
          Length = 644

 Score = 30.8 bits (68), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 20/57 (35%), Positives = 33/57 (57%), Gaps = 2/57 (3%)
 Frame = -1

Query: 154 VKLADFGVAGQLTDTQIKRNTF-VGTPFWMAPEVIKQSA-YDFKADIWSLGITAIEL 208
           +K+ADFG+A ++    ++  T  V T ++ APE++     Y    DIWSLG   +E+
Sbjct: 572 MKIADFGLA-RVFGLPVRTYTHEVITLWYRAPEILLGCRFYSVPVDIWSLGCIFVEM 405
>29011
          Length = 374

 Score = 30.0 bits (66), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 15/44 (34%), Positives = 25/44 (56%), Gaps = 1/44 (2%)
 Frame = +2

Query: 230 NNPPTLEGHHSK-PFKEFVEACLNKDPRFRPTAKELLKHKFITR 272
            +P +L G   +  FK F++ CL  +   R +A +LL H F+T+
Sbjct: 50  EDPKSLHGIQRRLIFKTFLDKCLQVEVESRSSAVDLLTHPFLTK 181
>31789
          Length = 676

 Score = 30.0 bits (66), Expect = 1.7,   Method: Compositional matrix adjust.
 Identities = 14/25 (56%), Positives = 17/25 (68%), Gaps = 1/25 (4%)
 Frame = +2

Query: 16  PEELFTKLD-RIGKGSFGEVYKGID 39
           P+  F K D  IG+GSF  VYKG+D
Sbjct: 311 PDNRFLKFDVEIGRGSFKTVYKGLD 385
>32357
          Length = 625

 Score = 30.0 bits (66), Expect = 1.7,   Method: Compositional matrix adjust.
 Identities = 12/24 (50%), Positives = 17/24 (70%)
 Frame = -2

Query: 23  LDRIGKGSFGEVYKGIDNHTKEVV 46
           + +IG GSFGE+Y G+ N + E V
Sbjct: 423 MKKIGSGSFGEIYLGVHNTSGEEV 352
>16350
          Length = 1108

 Score = 30.0 bits (66), Expect = 1.8,   Method: Compositional matrix adjust.
 Identities = 21/59 (35%), Positives = 27/59 (45%)
 Frame = +2

Query: 154 VKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDFKADIWSLGITAIELAKGE 212
           VK+AD G A     T       + T  +   EV+  + Y   ADIWS    A ELA G+
Sbjct: 356 VKIADLGNACW---TYHHFTEDIQTRQYRCLEVLIGAGYGTPADIWSTACMAFELATGD 523
>08233
          Length = 2477

 Score = 29.3 bits (64), Expect = 3.2,   Method: Compositional matrix adjust.
 Identities = 22/73 (30%), Positives = 33/73 (45%)
 Frame = -3

Query: 107  LKPGPLEETYIATILREILKGLDYLHSERKIHRDIKAANVLLSEQGDVKLADFGVAGQLT 166
            L PG  E+T+I      +      LHS R +HR       ++ + G +  AD     +L 
Sbjct: 2418 LTPGFGEKTFIVQGFGNV-----GLHSMRYLHRAGAKCIGIMEKDGSIYNADGIHPRELE 2254

Query: 167  DTQIKRNTFVGTP 179
            D +I+  T VG P
Sbjct: 2253 DYKIENGTIVGFP 2215
>11541
          Length = 1193

 Score = 28.9 bits (63), Expect = 3.8,   Method: Compositional matrix adjust.
 Identities = 12/21 (57%), Positives = 15/21 (71%)
 Frame = +1

Query: 250 CLNKDPRFRPTAKELLKHKFI 270
           C+ KDP  RPTA+ELL H  +
Sbjct: 4   CIQKDPDKRPTARELLFHAVL 66
>03106
          Length = 2384

 Score = 28.9 bits (63), Expect = 3.9,   Method: Compositional matrix adjust.
 Identities = 20/74 (27%), Positives = 34/74 (45%), Gaps = 1/74 (1%)
 Frame = +2

Query: 189 QSAYDF-KADIWSLGITAIELAKGEPPNSDLHPMRVLFLIPKNNPPTLEGHHSKPFKEFV 247
           +S  D+ KAD+W+ G  A E+     P    +         +++ P+L G   +     V
Sbjct: 5   ESVLDYSKADVWAAGAVAYEIFGASNP---FYSRLDSACYSQHDLPSLPGDTPEGVVRLV 175

Query: 248 EACLNKDPRFRPTA 261
            + L +DP  RP+A
Sbjct: 176 TSMLERDPAQRPSA 217
>00638
          Length = 1595

 Score = 28.9 bits (63), Expect = 4.7,   Method: Compositional matrix adjust.
 Identities = 11/24 (45%), Positives = 17/24 (70%)
 Frame = +2

Query: 121 LREILKGLDYLHSERKIHRDIKAA 144
           L E++K LD+ HS   +HRD+K +
Sbjct: 434 LYELMKALDFCHSMGIMHRDVKPS 505
>29722
          Length = 352

 Score = 28.5 bits (62), Expect = 5.4,   Method: Composition-based stats.
 Identities = 14/50 (28%), Positives = 26/50 (52%)
 Frame = -3

Query: 223 VLFLIPKNNPPTLEGHHSKPFKEFVEACLNKDPRFRPTAKELLKHKFITR 272
           +++ I K   P +   +S   +E + A L +DP  RP+   +L+  +I R
Sbjct: 323 LVYKILKGKLPPMPRQYSLDIQELLRAMLYQDPAKRPSINRILRDPYIRR 174
>18929
          Length = 440

 Score = 28.5 bits (62), Expect = 5.6,   Method: Compositional matrix adjust.
 Identities = 15/53 (28%), Positives = 26/53 (49%), Gaps = 6/53 (11%)
 Frame = +1

Query: 243 FKEFVEACLNKDPRFRPTAKELLKHKFITRYTKK------TSFLTELIDRYKR 289
            ++ +   ++ DPR RPTA +LL H  +    K+         L++ I R +R
Sbjct: 58  LQQVIRRMMSPDPRQRPTANQLLAHPTLAALQKEDKSMVILKLLSKCIRRSRR 216
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|149252550|ref|XP_485391.4| PREDICTED: FK506 binding
protein 15 [Mus musculus]
         (1324 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

11942                                                                 222   6e-58
00162                                                                  46   1e-04
37000                                                                  32   2.5  
09201                                                                  32   2.5  
00011                                                                  31   2.6  
04616                                                                  30   5.0  
38595                                                                  29   9.9  
>11942
          Length = 2252

 Score =  222 bits (566), Expect = 6e-58,   Method: Compositional matrix adjust.
 Identities = 134/349 (38%), Positives = 217/349 (62%)
 Frame = +1

Query: 581 PSVTSQLQPVRPLYPAPLSQAPHFQGSGDMMSFLMTEARQHNTEIRMAVNKVADKMDHLM 640
           P   SQ Q + P    PLS A        M   L++E RQ NTE+RMAV+K+ADK+D ++
Sbjct: 259 PLAASQPQGLMP-QATPLSDA--------MAPLLLSETRQQNTEMRMAVSKMADKVDRIL 411

Query: 641 TKVEELQKHSSGNSMLLPSMSVTMETSMIMSNIQRIIQENERLKQELLEKSSRIEEQNDK 700
            KVE +    +     LP+   TMETS+++ NI RI+QENERLK+E+ E+  +I+ QN+K
Sbjct: 412 DKVETISGQGT-QQQALPA--PTMETSILLHNISRIVQENERLKKEVFERGEKIDTQNEK 582

Query: 701 ISDLIERNQRYVEQSNLMMEKRNNSLQTATENTQARILHAEQEKAKVTEELAAATAQVSH 760
           I++L+++NQRYVE+SN ++E+RN   +     +Q+RIL  EQEK  +  EL++++AQ++ 
Sbjct: 583 IAELLQKNQRYVEKSNSLLEERNEGYKLTANQSQSRILXLEQEKVHMATELSSSSAQMAT 762

Query: 761 LQLKMTAHQKKETELQLQLTDNLKETDLLRGHVTRLQADLSELREASEQTQTKFKSEKQS 820
           LQL++   +KKE EL+ QL      +   +  + RL+   +E  +      +  + EK +
Sbjct: 763 LQLELGELRKKEGELRQQLQSTSSTSSSHQEELERLRLQRTEDEKKISDLTSSLREEKTA 942

Query: 821 RRQLELKVTSLEEELTDLRAEKTSLEKNLSERKKKSAQERCQAEAEMDEIRKSHQEELDR 880
           R+Q + ++TS++EEL DL++   +LE+NL+ERK+K+  ER + E E DE +  ++EE+  
Sbjct: 943 RKQSDQQMTSVQEELADLKSTCDTLERNLNERKRKAVDERKKLEEEADEAKAGYEEEIKT 1122

Query: 881 LRQLLKKARVSTDXXXXXXXXXXXXXXXXXWEAKCEQLLASARDEHLQQ 929
           LR+ L++ R +TD                 W+AKC++L+A+A D+H +Q
Sbjct: 1123LREKLRRQRTNTDVQTADKVAKLEEEMAGEWQAKCDKLVAAAADKHARQ 1269
>00162
          Length = 2322

 Score = 45.8 bits (107), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 38/123 (30%), Positives = 57/123 (46%), Gaps = 2/123 (1%)
 Frame = +2

Query: 276  VAKCNSISSLDAVLCQDLVAAEGPAVETGDSLEVAYTGWLLQNHVLGQVFDSTANKDKPL 335
            V K  +++   +V  +D     GP  + G  + V Y+G L +N+   + FDS   K KP 
Sbjct: 1877 VGKRRTVAGGTSV--EDSKVGHGPEAKPGHLVSVYYSGTLAKNN---KRFDSCL-KGKPF 2038

Query: 336  RLKLGSGKVVXXXXXXXXXXXXXXXXXIITPSACAAGS--EGVIGWTQPTDSILVFEVEV 393
            R KLG G+V+                 I  PS+   G+  +G I    P  S LVF+VE+
Sbjct: 2039 RFKLGRGEVIKGWDNGLIGMRVGGKRKITVPSSQGYGNSRQGPI----PPGSTLVFDVEL 2206

Query: 394  RRV 396
            + V
Sbjct: 2207 KAV 2215
>37000
          Length = 492

 Score = 31.6 bits (70), Expect = 2.5,   Method: Compositional matrix adjust.
 Identities = 23/73 (31%), Positives = 43/73 (58%), Gaps = 6/73 (8%)
 Frame = -3

Query: 823 QLELKVTSLEEELTDLRAEKTSLEKNLSERKKKSAQERCQAE------AEMDEIRKSHQE 876
           QLE +    ++ L +L  +K++L++NL E + K+++E+ +        +  D + K+ + 
Sbjct: 481 QLESQKKEAQKRLDELDDKKSNLDRNLKEMRDKTSKEQMEVNKLKSQISNQDRLVKNQEG 302

Query: 877 ELDRLRQLLKKAR 889
           ELD LRQ L+K R
Sbjct: 301 ELDSLRQELQKLR 263
>09201
          Length = 754

 Score = 31.6 bits (70), Expect = 2.5,   Method: Compositional matrix adjust.
 Identities = 36/152 (23%), Positives = 65/152 (42%), Gaps = 1/152 (0%)
 Frame = -1

Query: 738 LHAEQEKAKVTEELAAATAQVSHLQLKMTAHQKKETELQLQLTDNLKETDLLRGHVTRLQ 797
           L  E + A+++EEL A+ A+V+  + K+ AH K+                          
Sbjct: 628 LCTESDTARLSEELGASQARVAQAEAKLAAHDKQHDR----------------------- 518

Query: 798 ADLSELREASEQTQTKFKSEKQS-RRQLELKVTSLEEELTDLRAEKTSLEKNLSERKKKS 856
            D++EL       + K+KSE  S RR  +  V    + +  +R++   + +N    +++ 
Sbjct: 517 -DMAEL-------ENKYKSEMDSVRRARDEAVEQHTQSINKIRSQSQQMSENERVYRQRL 362

Query: 857 AQERCQAEAEMDEIRKSHQEELDRLRQLLKKA 888
              RC+ EA         Q EL   R+L++ A
Sbjct: 361 DSARCELEA--------LQNELSSRRELIRSA 290
>00011
          Length = 1711

 Score = 31.2 bits (69), Expect = 2.6,   Method: Composition-based stats.
 Identities = 17/38 (44%), Positives = 24/38 (63%)
 Frame = +2

Query: 302 ETGDSLEVAYTGWLLQNHVLGQVFDSTANKDKPLRLKL 339
           + GDS++V YTG L      G+ FDS+ ++ KP  LKL
Sbjct: 155 KAGDSVQVHYTGTLTN----GKKFDSSRDRGKPFVLKL 256
>04616
          Length = 1115

 Score = 30.4 bits (67), Expect = 5.0,   Method: Compositional matrix adjust.
 Identities = 18/52 (34%), Positives = 30/52 (57%), Gaps = 3/52 (5%)
 Frame = +3

Query: 462 NPDTVKAKLISRMAKMGQPMLPILPPQLDSNDSETED---ATVLRGAGQSLV 510
           +P TV  +L+  +A  G   LP+ PP  D +D +T++   A+ L+ +GQ L 
Sbjct: 786 DPCTVHQRLVGVVAVSGH-ALPVFPPPPDLHDGQTDESC*ASSLQQSGQYLC 938
>38595
          Length = 399

 Score = 29.3 bits (64), Expect = 9.9,   Method: Compositional matrix adjust.
 Identities = 13/30 (43%), Positives = 18/30 (60%)
 Frame = +1

Query: 513 SIQPSLQPAHPVLPQMASQAPQPSGSGLQT 542
           S QPS+QP  P  P +  + P  SG+G+ T
Sbjct: 190 SAQPSVQPGSPRKPSLFDRPPTRSGNGIST 279
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|164519124|ref|NP_083798.2| LGN protein [Mus musculus]
         (679 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

22872                                                                 169   1e-57
30597                                                                 100   3e-35
37021                                                                  34   0.17 
22644                                                                  30   3.5  
34628                                                                  29   5.4  
>22872
          Length = 459

 Score =  169 bits (427), Expect(2) = 1e-57,   Method: Compositional matrix adjust.
 Identities = 81/110 (73%), Positives = 90/110 (81%)
 Frame = +2

Query: 100 GEAKASGNLGNTLKVLGNFDEAIVCCQRHLDISRELNDKVGEARALYNLGNVYHAKGKSF 159
           GEAKASGNLGNTLKV+G FDEAIVCC RHL+ISRELNDK+GEARALYNLGNV+H KGK  
Sbjct: 128 GEAKASGNLGNTLKVIGKFDEAIVCCMRHLEISRELNDKLGEARALYNLGNVWHTKGKQM 307

Query: 160 GCPGPQDTGEFPEDVRNALQAAVDLYEENLSLVTALGDRAAQGRAFGNLG 209
           G  G QD GEFP  V+  LQ A   Y++NLSLV  LGD++AQGRA GNLG
Sbjct: 308 GRTGNQDPGEFPPQVKECLQKAAQFYQDNLSLVKELGDKSAQGRACGNLG 457

 Score = 73.9 bits (180), Expect(2) = 1e-57,   Method: Compositional matrix adjust.
 Identities = 35/46 (76%), Positives = 39/46 (84%)
 Frame = +3

Query: 58  LKTLSAIYSQLGNAYFYLHDYAKALEYHHHDLTLARTIGDQLGEAK 103
           LKTL AIYSQLGNAYFYL DYAKALEYH HDL LART  D++G+ +
Sbjct: 3   LKTLGAIYSQLGNAYFYLQDYAKALEYHKHDLNLARTCQDRVGKPR 140

 Score = 56.2 bits (134), Expect(2) = 3e-13,   Method: Compositional matrix adjust.
 Identities = 35/109 (32%), Positives = 59/109 (54%), Gaps = 20/109 (18%)
 Frame = +2

Query: 281 EAQSCYSLGNTYTLLQDYEKAIDYHLKHLAIAQELKDRIGEGRACWSLGNAYTA------ 334
           EA++  +LGNT  ++  +++AI   ++HL I++EL D++GE RA ++LGN +        
Sbjct: 131 EAKASGNLGNTLKVIGKFDEAIVCCMRHLEISRELNDKLGEARALYNLGNVWHTKGKQMG 310

Query: 335 -LGNHD-------------QAMHFAEKHLEISREVGDKSGELTARLNLS 369
             GN D             +A  F + +L + +E+GDKS +  A  NL 
Sbjct: 311 RTGNQDPGEFPPQVKECLQKAAQFYQDNLSLVKELGDKSAQGRACGNLG 457

 Score = 37.4 bits (85), Expect(2) = 3e-13,   Method: Compositional matrix adjust.
 Identities = 18/35 (51%), Positives = 23/35 (65%)
 Frame = +3

Query: 245 YSNLGNAYIFLGEFETASEYYKKTLLLARQLKDRA 279
           YS LGNAY +L ++  A EY+K  L LAR  +DR 
Sbjct: 24  YSQLGNAYFYLQDYAKALEYHKHDLNLARTCQDRV 128

 Score = 45.4 bits (106), Expect(2) = 6e-11,   Method: Compositional matrix adjust.
 Identities = 24/57 (42%), Positives = 33/57 (57%)
 Frame = +2

Query: 320 GEGRACWSLGNAYTALGNHDQAMHFAEKHLEISREVGDKSGELTARLNLSDLQMVLG 376
           GE +A  +LGN    +G  D+A+    +HLEISRE+ DK GE  A  NL ++    G
Sbjct: 128 GEAKASGNLGNTLKVIGKFDEAIVCCMRHLEISRELNDKLGEARALYNLGNVWHTKG 298

 Score = 40.4 bits (93), Expect(2) = 6e-11,   Method: Compositional matrix adjust.
 Identities = 18/36 (50%), Positives = 25/36 (69%)
 Frame = +3

Query: 288 LGNTYTLLQDYEKAIDYHLKHLAIAQELKDRIGEGR 323
           LGN Y  LQDY KA++YH   L +A+  +DR+G+ R
Sbjct: 33  LGNAYFYLQDYAKALEYHKHDLNLARTCQDRVGKPR 140

 Score = 58.9 bits (141), Expect = 6e-09,   Method: Compositional matrix adjust.
 Identities = 32/111 (28%), Positives = 57/111 (51%), Gaps = 20/111 (18%)
 Frame = +2

Query: 199 AAQGRAFGNLGNTHYLLGNFRDAVIAHEQRLLIAKEFGDKAAERRAYSNLGNAYIFLGE- 257
             + +A GNLGNT  ++G F +A++   + L I++E  DK  E RA  NLGN +   G+ 
Sbjct: 125 GGEAKASGNLGNTLKVIGKFDEAIVCCMRHLEISRELNDKLGEARALYNLGNVWHTKGKQ 304

Query: 258 -------------------FETASEYYKKTLLLARQLKDRAVEAQSCYSLG 289
                               + A+++Y+  L L ++L D++ + ++C +LG
Sbjct: 305 MGRTGNQDPGEFPPQVKECLQKAAQFYQDNLSLVKELGDKSAQGRACGNLG 457

 Score = 54.3 bits (129), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 35/118 (29%), Positives = 59/118 (50%), Gaps = 20/118 (16%)
 Frame = +2

Query: 232 AKEFGDKAAERRAYSNLGNAYIFLGEFETASEYYKKTLLLARQLKDRAVEAQSCYSLGNT 291
            K+      E +A  NLGN    +G+F+ A     + L ++R+L D+  EA++ Y+LGN 
Sbjct: 104 GKDVSGPGGEAKASGNLGNTLKVIGKFDEAIVCCMRHLEISRELNDKLGEARALYNLGNV 283

Query: 292 Y---------TLLQD-----------YEKAIDYHLKHLAIAQELKDRIGEGRACWSLG 329
           +         T  QD            +KA  ++  +L++ +EL D+  +GRAC +LG
Sbjct: 284 WHTKGKQMGRTGNQDPGEFPPQVKECLQKAAQFYQDNLSLVKELGDKSAQGRACGNLG 457

 Score = 38.1 bits (87), Expect = 0.011,   Method: Compositional matrix adjust.
 Identities = 30/102 (29%), Positives = 44/102 (43%), Gaps = 20/102 (19%)
 Frame = +2

Query: 68  LGNAYFYLHDYAKALEYHHHDLTLARTIGDQLGEAKASGNLGNTLKVLGN---------- 117
           LGN    +  + +A+      L ++R + D+LGEA+A  NLGN     G           
Sbjct: 152 LGNTLKVIGKFDEAIVCCMRHLEISRELNDKLGEARALYNLGNVWHTKGKQMGRTGNQDP 331

Query: 118 --FDEAIVCC--------QRHLDISRELNDKVGEARALYNLG 149
             F   +  C        Q +L + +EL DK  + RA  NLG
Sbjct: 332 GEFPPQVKECLQKAAQFYQDNLSLVKELGDKSAQGRACGNLG 457
>30597
          Length = 734

 Score =  100 bits (249), Expect(2) = 3e-35,   Method: Compositional matrix adjust.
 Identities = 48/96 (50%), Positives = 71/96 (73%)
 Frame = +3

Query: 326 WSLGNAYTALGNHDQAMHFAEKHLEISREVGDKSGELTARLNLSDLQMVLGLSYSTNNSM 385
           WSLGNA++ALGNH+ A+ FA KHLEIS+E+GD++G++TA++N++D + +LG+    + S 
Sbjct: 3   WSLGNAHSALGNHESALEFANKHLEISKEIGDETGQMTAQMNMTDFRAMLGMIPVADKSG 182

Query: 386 MSENIEIDGSLHGAGAKLGRRHSMENLELMKLTPEK 421
            SE    D +L     +  RR SMEN+E+MKLTP+K
Sbjct: 183 RSETDTADVALK--RPERARRFSMENMEIMKLTPDK 284

 Score = 67.4 bits (163), Expect(2) = 3e-35,   Method: Compositional matrix adjust.
 Identities = 55/151 (36%), Positives = 75/151 (49%), Gaps = 4/151 (2%)
 Frame = +1

Query: 449 RLKGKKYKSGSACTKVLQDASNSVDHRAPRSQKKISS--DTIGDEGFFDLLRRFQSNRMD 506
           R K K  KS S  T +   A    D    R QKK +   + + D+GFFD L RFQS R+D
Sbjct: 310 RPKQKVQKSASIATDMDHCAHTPAD----REQKKPNGMMEDLDDDGFFDQLSRFQSRRID 477

Query: 507 DQRCHLQGNCRXXXXXXXXXXPKLMKAPSVSVVSPNTDEFLDLLASSQSRRLDDQRASFS 566
           DQRC  +               +  K  +  V SP  +E +DL+A  Q  R++DQRAS  
Sbjct: 478 DQRCSFR--LLESGATSPTHSSQDCKDLAALVASPAREELMDLVAGFQVSRMNDQRASLP 651

Query: 567 NLPGLRLTKGNSPSVLERLMT--NDKKEPDE 595
           + PGL     NS  V+ +L+T  +D   PD+
Sbjct: 652 SFPGL-----NSGDVISQLLTQSSDLDVPDD 729

 Score = 39.7 bits (91), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 27/104 (25%), Positives = 46/104 (44%), Gaps = 4/104 (3%)
 Frame = +3

Query: 107 NLGNTLKVLGNFDEAIVCCQRHLDISRELNDKVGEARALYNLGNVYHAKGKSFGCPGPQD 166
           +LGN    LGN + A+    +HL+IS+E+ D+ G+  A  N+ +     G     P    
Sbjct: 6   SLGNAHSALGNHESALEFANKHLEISKEIGDETGQMTAQMNMTDFRAMLGM---IPVADK 176

Query: 167 TGEFPEDVRNAL----QAAVDLYEENLSLVTALGDRAAQGRAFG 206
           +G    D  +      + A     EN+ ++    D+   GR +G
Sbjct: 177 SGRSETDTADVALKRPERARRFSMENMEIMKLTPDKKG*GRGWG 308

 Score = 35.0 bits (79), Expect = 0.11,   Method: Compositional matrix adjust.
 Identities = 17/49 (34%), Positives = 30/49 (61%)
 Frame = +3

Query: 68  LGNAYFYLHDYAKALEYHHHDLTLARTIGDQLGEAKASGNLGNTLKVLG 116
           LGNA+  L ++  ALE+ +  L +++ IGD+ G+  A  N+ +   +LG
Sbjct: 9   LGNAHSALGNHESALEFANKHLEISKEIGDETGQMTAQMNMTDFRAMLG 155

 Score = 34.3 bits (77), Expect = 0.19,   Method: Compositional matrix adjust.
 Identities = 19/55 (34%), Positives = 27/55 (49%)
 Frame = +3

Query: 207 NLGNTHYLLGNFRDAVIAHEQRLLIAKEFGDKAAERRAYSNLGNAYIFLGEFETA 261
           +LGN H  LGN   A+    + L I+KE GD+  +  A  N+ +    LG    A
Sbjct: 6   SLGNAHSALGNHESALEFANKHLEISKEIGDETGQMTAQMNMTDFRAMLGMIPVA 170

 Score = 32.0 bits (71), Expect = 0.86,   Method: Compositional matrix adjust.
 Identities = 30/98 (30%), Positives = 44/98 (44%), Gaps = 18/98 (18%)
 Frame = +1

Query: 594 DEDFFDILVKCQGSRLDDQRCA---PPSAATKGPTVPDED---------------FFSLI 635
           D+ FFD L + Q  R+DDQRC+     S AT  PT   +D                  L+
Sbjct: 427 DDGFFDQLSRFQSRRIDDQRCSFRLLESGAT-SPTHSSQDCKDLAALVASPAREELMDLV 603

Query: 636 LRSQAKRMDEQRVLLQRDPNRDSEFGLKELLQNNALLE 673
              Q  RM++QR  L   P  +S   + +LL  ++ L+
Sbjct: 604 AGFQVSRMNDQRASLPSFPGLNSGDVISQLLTQSSDLD 717
>37021
          Length = 232

 Score = 34.3 bits (77), Expect = 0.17,   Method: Composition-based stats.
 Identities = 13/16 (81%), Positives = 14/16 (87%)
 Frame = +1

Query: 31  GERLCKSGDCRAGVSF 46
           G RLCK+GDCRAGV F
Sbjct: 184 GGRLCKAGDCRAGVQF 231
>22644
          Length = 1600

 Score = 30.0 bits (66), Expect = 3.5,   Method: Compositional matrix adjust.
 Identities = 14/59 (23%), Positives = 35/59 (59%)
 Frame = +1

Query: 245 YSNLGNAYIFLGEFETASEYYKKTLLLARQLKDRAVEAQSCYSLGNTYTLLQDYEKAID 303
           +S LGNAY+ + +   A +++ +   + ++ +   + +++  +LG T+   +D+ KA+D
Sbjct: 934 HSLLGNAYLEVRDLGNAFKHHSEDFRIGQEKQYPNITSRALANLGRTHVFRKDFTKALD 1110
>34628
          Length = 545

 Score = 29.3 bits (64), Expect = 5.4,   Method: Composition-based stats.
 Identities = 23/88 (26%), Positives = 46/88 (52%), Gaps = 7/88 (7%)
 Frame = +1

Query: 253 IFLGEFETASEYYKKTLLLARQLKDRAVE------AQSCYSLGNTYTLLQDYEKAIDYHL 306
           I + ++++A  Y ++    AR ++D   E        + + LG  +T+  D +KAI+ + 
Sbjct: 4   ISMKQYQSAVHYLEQ----ARDIQDVLEEDIKGDLVSTLHQLGQMHTMAGDIDKAIESYR 171

Query: 307 KHLAIAQEL-KDRIGEGRACWSLGNAYT 333
           + L + +E+  D++G    C +LGN  T
Sbjct: 172 ESLDVFREMHNDQLGP-EMCVTLGNLAT 252

 Score = 29.3 bits (64), Expect = 5.6,   Method: Composition-based stats.
 Identities = 27/73 (36%), Positives = 38/73 (52%), Gaps = 8/73 (10%)
 Frame = +1

Query: 87  HDLTLARTIGDQLGEAKASGNLGNTLKVLG-------NFDEAIVCCQRHLDISREL-NDK 138
           H L  AR I D L E    G+L +TL  LG       + D+AI   +  LD+ RE+ ND+
Sbjct: 34  HYLEQARDIQDVL-EEDIKGDLVSTLHQLGQMHTMAGDIDKAIESYRESLDVFREMHNDQ 210

Query: 139 VGEARALYNLGNV 151
           +G    +  LGN+
Sbjct: 211 LGPEMCV-TLGNL 246
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|33859596|ref|NP_035160.1| procollagen-proline,
2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha 1
polypeptide [Mus musculus]
         (534 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

30950                                                                 219   1e-57
36907                                                                 201   5e-52
34965                                                                 107   1e-23
>30950
          Length = 860

 Score =  219 bits (559), Expect = 1e-57,   Method: Compositional matrix adjust.
 Identities = 119/278 (42%), Positives = 169/278 (60%), Gaps = 4/278 (1%)
 Frame = +3

Query: 160 SFLTAEDCFELGKVAYTEADYYHTELWMEQALTQLEEG----ELSTVDKVSVLDYLSYAV 215
           + + + DCF LG+++Y + D YHT LWM++AL   +E     E  TVD+  VLDYL+Y +
Sbjct: 48  NIIDSGDCFLLGRLSYNQKDMYHTVLWMQEALDIDKESYSAPENRTVDRTEVLDYLAYTM 227

Query: 216 YQQGXXXXXXXXXXXXXXXXPEHQRANGNLVYFEYIMSKEKDANKSASGDQSDQKTAPKK 275
             QG                P H+RA  N  YF  ++ +     ++ SG  S ++ A ++
Sbjct: 228 AVQGHVQHALTLTNELLDINPNHERAFNNKQYFVDMLVQR---GETPSG--SAERPALER 392

Query: 276 KGIAVDYLPERQKYEMLCRGEGIKMTPRRQKRLFCRYHDGNRNPKFILAPAKQEDEWDKP 335
           +  +     E Q YE LCRGE  +   + + +L CRY   N +P  +L P KQE+    P
Sbjct: 393 QVDSYRQSTEFQTYESLCRGEFTRKI-KDEHKLKCRYF-TNGDPXLLLQPLKQEEVHLDP 566

Query: 336 RIIRFHDIISDAEIEIVKDLAKPRLRRATISNPVTGALETVHYRISKSAWLSGYEDPVVS 395
            I+ +HD++S+ ++  +K +A PRL RAT+ N VTG LE   YRISKSAWL G + P V+
Sbjct: 567 WIVLYHDVLSEEDMRDIKMMATPRLNRATVQNSVTGELEVAQYRISKSAWLKGTDHPTVA 746

Query: 396 RINMRIQDLTGLDVSTAEELQVANYGVGGQYEPHFDFA 433
           ++N RIQ +TGLD+ TAEELQ+ANYG+GGQYEPHFDFA
Sbjct: 747 KVNQRIQAVTGLDMDTAEELQIANYGIGGQYEPHFDFA 860
>36907
          Length = 755

 Score =  201 bits (512), Expect = 5e-52,   Method: Compositional matrix adjust.
 Identities = 95/235 (40%), Positives = 145/235 (61%)
 Frame = -2

Query: 296 EGIKMTPRRQKRLFCRYHDGNRNPKFILAPAKQEDEWDKPRIIRFHDIISDAEIEIVKDL 355
           E +K +P  Q++L CR H G  N +FI  P K E+    P I++ HD+IS  E   ++ +
Sbjct: 730 EELKPSPASQRKLRCRLHSG-MNQEFIYQPYKLEELQLDPYIVQVHDVISAKETVELQKM 554

Query: 356 AKPRLRRATISNPVTGALETVHYRISKSAWLSGYEDPVVSRINMRIQDLTGLDVSTAEEL 415
           A+P L+R+ + N       + ++R S+       + P++ ++   ++ L+GLD+ +AE L
Sbjct: 553 ARPELQRSKVYNVGGNEHISANFRTSQGTSFEYDQHPIMQKMRRHVEQLSGLDMRSAEAL 374

Query: 416 QVANYGVGGQYEPHFDFARKDEPDAFRELGTGNRIATWLFYMSDVSAGGATVFPEVGASV 475
           Q+ANYG+GG YEPH D    D         + NRIAT ++Y+S+V AGG T FP +   V
Sbjct: 373 QIANYGIGGHYEPHMDSFPDDHDYGINLYKSTNRIATAIYYLSNVEAGGGTAFPYLPLLV 194

Query: 476 WPKKGTAVFWYNLFASGEGDYSTRHAACPVLVGNKWVSNKWLHERGQEFRRPCTL 530
            P++G+ +FWYNL  SG+ DY T+HAACPVL+G+KW++N W+H   Q+  RPC L
Sbjct: 193 TPERGSLLFWYNLHRSGDPDYRTKHAACPVLLGSKWIANVWIHLYNQDTIRPCEL 29
>34965
          Length = 345

 Score =  107 bits (267), Expect = 1e-23,   Method: Composition-based stats.
 Identities = 44/55 (80%), Positives = 49/55 (89%)
 Frame = -2

Query: 477 PKKGTAVFWYNLFASGEGDYSTRHAACPVLVGNKWVSNKWLHERGQEFRRPCTLS 531
           PKKGTA FWYNL+ +G+G Y TRHAACPVLVG KWV+NKW+HERGQEFRRPC LS
Sbjct: 344 PKKGTAAFWYNLYKNGDGIYDTRHAACPVLVGVKWVANKWIHERGQEFRRPCDLS 180
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6753882|ref|NP_034349.1| FK506 binding protein 52
[Mus musculus]
         (458 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

00888                                                                 220   1e-57
00011                                                                  69   1e-19
03857                                                                  91   1e-18
13560                                                                  80   2e-15
00162                                                                  67   2e-11
01124                                                                  49   3e-06
35348                                                                  44   2e-04
37162                                                                  39   0.004
30337                                                                  39   0.006
26568                                                                  35   0.048
04645                                                                  32   0.46 
13998                                                                  32   0.54 
07635                                                                  30   2.2  
05037                                                                  30   2.2  
03995                                                                  30   2.7  
22027                                                                  28   8.5  
>00888
          Length = 970

 Score =  220 bits (560), Expect = 1e-57,   Method: Compositional matrix adjust.
 Identities = 112/226 (49%), Positives = 152/226 (67%), Gaps = 1/226 (0%)
 Frame = -3

Query: 194 EGESLDLPCGLEEAIQRMEKGEHSIVYLKPSYAFGSVGKERFQIPPHAELRYEVRLKSFE 253
           EG+   +  G+E A  +M+KGE   + +   YA+G  G  RF IP +A L Y V + +FE
Sbjct: 968 EGDEEGIIAGIELATLKMKKGERDQLTVASKYAYGEEGCXRFNIPSNATLVYNVEMVNFE 789

Query: 254 KAKESWEMSSAEKLEQSNIVKERGTAYFKEGKYKQALLQYKKIVSWLEYESS-FSGEEMQ 312
           KAK+SWEM   EK+EQS I+KE+GTA FK+GKY++AL  Y+KIVS+LE+ES+  S  E+ 
Sbjct: 788 KAKQSWEMDVGEKIEQSKIIKEKGTAAFKKGKYQRALTNYEKIVSFLEHESTGLSDSELS 609

Query: 313 KVHALRLASHLNLAMCHLKLQAFSAAIESCNKALELDSNNEKGLFRRGEAHLAVNDFDLA 372
             H L +A+ LN+AMC LKL  +  A E+CNK L + +NN K LFRRG+A L   D+  A
Sbjct: 608 DKHQLMVAAFLNIAMCQLKLLDYRQAEETCNKVLAMSTNNVKALFRRGQARLECADYTEA 429

Query: 373 RADFQKVLQLYPSNKAAKTQLAVCQQRTRRQLAREKKLYANMFERL 418
            +DF KVL+L P NKAAK Q  VC Q+ +   A+EK LY NMF+++
Sbjct: 428 ASDFSKVLELEPGNKAAKNQHIVCLQKQKADYAKEKALYTNMFQKM 291
>00011
          Length = 1711

 Score = 69.3 bits (168), Expect(2) = 1e-19,   Method: Compositional matrix adjust.
 Identities = 32/58 (55%), Positives = 38/58 (65%)
 Frame = +1

Query: 79  FDLGKGEVIKAWDIAVATMKVGEVCHITCKPEYAYGAAGSPPKIPPNATLVFEVELFE 136
           F +G G+VIKAWD  V  M VGE   +T  P+YAYG  G    IPPNATL+F+VEL  
Sbjct: 247 FKIGTGQVIKAWDEGVMKMSVGERATLTASPDYAYGRNGIGDIIPPNATLIFDVELLS 420

 Score = 45.1 bits (105), Expect(2) = 1e-19,   Method: Compositional matrix adjust.
 Identities = 23/42 (54%), Positives = 25/42 (59%)
 Frame = +2

Query: 40  EGTGTETPMIGDRVFVHYTGWLLDGTKFDSSLDRKDKFSFDL 81
           EG G+  P  GD V VHYTG L +G KFDSS DR   F   L
Sbjct: 131 EGDGSTYPKAGDSVQVHYTGTLTNGKKFDSSRDRGKPFVLKL 256

 Score = 42.7 bits (99), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 21/66 (31%), Positives = 36/66 (54%)
 Frame = +1

Query: 186 RELCFEVGEGESLDLPCGLEEAIQRMEKGEHSIVYLKPSYAFGSVGKERFQIPPHAELRY 245
           + +CF++G G+ +      +E + +M  GE + +   P YA+G  G     IPP+A L +
Sbjct: 235 QAICFKIGTGQVIK---AWDEGVMKMSVGERATLTASPDYAYGRNGIGDI-IPPNATLIF 402

Query: 246 EVRLKS 251
           +V L S
Sbjct: 403 DVELLS 420
>03857
          Length = 1696

 Score = 90.5 bits (223), Expect = 1e-18,   Method: Compositional matrix adjust.
 Identities = 52/147 (35%), Positives = 79/147 (53%), Gaps = 4/147 (2%)
 Frame = +1

Query: 273 VKERGTAYFKEGKYKQALLQYKKIVSWLEY--ESSFSGEEMQKV--HALRLASHLNLAMC 328
           VK+ G   FK GK+  A  +YKK + +L+   E     E+ QK     L +   LN A C
Sbjct: 472 VKQAGNTLFKAGKFGPANRKYKKALRYLQKLDEEQKMSEDQQKAMEKELHIPVSLNAAAC 651

Query: 329 HLKLQAFSAAIESCNKALELDSNNEKGLFRRGEAHLAVNDFDLARADFQKVLQLYPSNKA 388
            LKL  ++ A+E C + LE D +N K  +R+G+AH    D++ A A FQK L   P +K 
Sbjct: 652 CLKLNKYNEALEYCQEVLEADPDNSKAQYRQGQAHAGNKDYETALASFQKALAANPDDKG 831

Query: 389 AKTQLAVCQQRTRRQLAREKKLYANMF 415
            K ++   ++    +  REK++Y+ MF
Sbjct: 832 IKLEIQKVKRTVEEEKKREKQMYSRMF 912
>13560
          Length = 978

 Score = 79.7 bits (195), Expect = 2e-15,   Method: Compositional matrix adjust.
 Identities = 50/153 (32%), Positives = 75/153 (49%), Gaps = 6/153 (3%)
 Frame = +1

Query: 242 ELRYEVRLKSFEKAKESWEMSSAEKLEQSNIVKERGTAYFKEGKYKQALLQYKK----IV 297
           E  + V L  F  A   W ++  EK   +++ KE+G  YFK G    A   ++     ++
Sbjct: 106 EFVFHVTLHDFTSATPPWRLTPLEKYSSASVHKEKGAQYFKTGNIFAAFSHFRTAIRLLL 285

Query: 298 SWLEYESSFSGEEMQKVHALRLAS--HLNLAMCHLKLQAFSAAIESCNKALELDSNNEKG 355
           S L Y  SFS +E+     L+L    +LNLA C +K       I +C  AL LD  N K 
Sbjct: 286 SVLPY--SFSDDEVASTSHLQLLCQCYLNLAACQIKSGHHKHVITNCTHALNLDPANVKA 459

Query: 356 LFRRGEAHLAVNDFDLARADFQKVLQLYPSNKA 388
           L+RR  A++ + +   A  D +  LQ  P+N+A
Sbjct: 460 LYRRASANVNLGNLLHAHEDLETGLQKEPNNRA 558
>00162
          Length = 2322

 Score = 66.6 bits (161), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 41/86 (47%), Positives = 49/86 (56%), Gaps = 1/86 (1%)
 Frame = +2

Query: 50   GDRVFVHYTGWLLDGTK-FDSSLDRKDKFSFDLGKGEVIKAWDIAVATMKVGEVCHITCK 108
            G  V V+Y+G L    K FDS L  K  F F LG+GEVIK WD  +  M+VG    IT  
Sbjct: 1955 GHLVSVYYSGTLAKNNKRFDSCLKGK-PFRFKLGRGEVIKGWDNGLIGMRVGGKRKITVP 2131

Query: 109  PEYAYGAAGSPPKIPPNATLVFEVEL 134
                YG +   P IPP +TLVF+VEL
Sbjct: 2132 SSQGYGNSRQGP-IPPGSTLVFDVEL 2206
>01124
          Length = 1372

 Score = 49.3 bits (116), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 36/132 (27%), Positives = 57/132 (43%), Gaps = 13/132 (9%)
 Frame = -3

Query: 272 IVKERGTAYFKEGKYKQALLQYKKIVSWLEYESSFSGEEMQKVHALRLASHL-----NLA 326
            ++++G  +F  G Y+ A+  Y                     HALRL   +     N A
Sbjct: 749 FLRDKGNGFFASGNYQAAVNVY--------------------THALRLNPKMPSLYSNRA 630

Query: 327 MCHLKLQAFSAAIESCNKALELDS--------NNEKGLFRRGEAHLAVNDFDLARADFQK 378
            CHLKL+     IE C+KA++L S        +  K + RRG A   +  +     D++ 
Sbjct: 629 ACHLKLRNLFKCIEDCSKAMDLLSPPVPQNAASRVKAMVRRGTAFCQLEMYVEGLQDYEA 450

Query: 379 VLQLYPSNKAAK 390
            L+L P+N+  K
Sbjct: 449 ALKLDPNNQQLK 414
>35348
          Length = 627

 Score = 43.5 bits (101), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 33/125 (26%), Positives = 60/125 (48%), Gaps = 2/125 (1%)
 Frame = -2

Query: 260 EMSSAEKLEQSNIVKERGTAYFKEGKYKQALLQYKK--IVSWLEYESSFSGEEMQKVHAL 317
           +M+  ++L ++  VK RG   FK G+Y +AL  Y +   +  L+Y               
Sbjct: 614 KMNLQKRLAEAVKVKVRGNDTFKSGQYAEALELYSEGLDICPLKYVQQ------------ 471

Query: 318 RLASHLNLAMCHLKLQAFSAAIESCNKALELDSNNEKGLFRRGEAHLAVNDFDLARADFQ 377
           R     N A C +K + +  A+  C K+++L+    K  FRR +A+  +   D A  D +
Sbjct: 470 RSVMLSNRAACRIKKEDYQKAVGDCTKSIDLNPAYIKAYFRRADAYEKLEKLDDALKDHR 291

Query: 378 KVLQL 382
           +V+++
Sbjct: 290 QVVEM 276
>37162
          Length = 601

 Score = 38.9 bits (89), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 25/76 (32%), Positives = 39/76 (51%), Gaps = 1/76 (1%)
 Frame = -2

Query: 50  GDRVFVHYTGWLLDGTKFDSSLDR-KDKFSFDLGKGEVIKAWDIAVATMKVGEVCHITCK 108
           GD V VHYTG+L  G  FDSS+   ++   F LG+ +VI  W++         VC    +
Sbjct: 582 GDGVAVHYTGYLETGAVFDSSVQAGREPLEFLLGERKVIPGWEMGX*R----NVCGRKAQ 415

Query: 109 PEYAYGAAGSPPKIPP 124
            +++  +   P  +PP
Sbjct: 414 VDHSSPSGJRPDWLPP 367
>30337
          Length = 493

 Score = 38.5 bits (88), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 23/64 (35%), Positives = 34/64 (53%)
 Frame = -1

Query: 324 NLAMCHLKLQAFSAAIESCNKALELDSNNEKGLFRRGEAHLAVNDFDLARADFQKVLQLY 383
           N A+C++KL+ +  A + C +ALELD N  KG F  G+A + +  +D A     K   L 
Sbjct: 214 NRALCYIKLRNWELASQDCQRALELDRNLVKGHFFLGQALVELAMYDEAITHLMKAHDLA 35

Query: 384 PSNK 387
              K
Sbjct: 34  KDQK 23
>26568
          Length = 398

 Score = 35.4 bits (80), Expect = 0.048,   Method: Compositional matrix adjust.
 Identities = 22/74 (29%), Positives = 37/74 (50%), Gaps = 5/74 (6%)
 Frame = +1

Query: 274 KERGTAYFKEGKYKQALLQYKKIVSWLEYESSFSG-----EEMQKVHALRLASHLNLAMC 328
           +ERG   F + +Y  ++  Y   + +L+  +SF G       +Q +   +L  + N+A  
Sbjct: 118 RERGNQLFSQEEYHSSINSYTLALKYLD--ASFGGLTGNTSVLQNIVDSKLKCYNNMAAA 291

Query: 329 HLKLQAFSAAIESC 342
            LK+ A  AAI SC
Sbjct: 292 QLKIGANDAAIHSC 333
>04645
          Length = 1075

 Score = 32.3 bits (72), Expect = 0.46,   Method: Compositional matrix adjust.
 Identities = 16/55 (29%), Positives = 30/55 (54%)
 Frame = +3

Query: 328 CHLKLQAFSAAIESCNKALELDSNNEKGLFRRGEAHLAVNDFDLARADFQKVLQL 382
            +LK+     AI  C+KA+EL+ ++ +G   RG+AH  +  ++ +  D     +L
Sbjct: 573 AYLKMGKPKKAIHDCSKAIELNPDSAQGYKWRGKAHKLLGHWEESYHDLTLACKL 737
>13998
          Length = 1075

 Score = 32.0 bits (71), Expect = 0.54,   Method: Compositional matrix adjust.
 Identities = 16/45 (35%), Positives = 25/45 (55%)
 Frame = +1

Query: 338 AIESCNKALELDSNNEKGLFRRGEAHLAVNDFDLARADFQKVLQL 382
           A+  CN+ L+L+S   K L  R   +  +  F+ A AD++  LQL
Sbjct: 1   AVADCNRVLDLNSQYLKALLLRARCNNDLEKFEEAVADYETALQL 135
>07635
          Length = 379

 Score = 30.0 bits (66), Expect = 2.2,   Method: Composition-based stats.
 Identities = 23/78 (29%), Positives = 36/78 (46%), Gaps = 4/78 (5%)
 Frame = +2

Query: 249 LKSFEKAKESWEMSSAEKLEQSNIVKERG----TAYFKEGKYKQALLQYKKIVSWLEYES 304
           L  F+ ++  W +S    + Q+   KE G    + + KE K  Q      +  S  E   
Sbjct: 155 LSCFKSSRPLWAISGLSTMIQTKSRKENGAHPNSVHVKEPKPGQTT---SRPHSTREQNC 325

Query: 305 SFSGEEMQKVHALRLASH 322
            +  EE+Q+VHAL  +SH
Sbjct: 326 WYPQEELQRVHALSQSSH 379
>05037
          Length = 723

 Score = 30.0 bits (66), Expect = 2.2,   Method: Compositional matrix adjust.
 Identities = 12/25 (48%), Positives = 19/25 (76%)
 Frame = +1

Query: 59  GWLLDGTKFDSSLDRKDKFSFDLGK 83
           G +L G++FD ++DR+ KFS  LG+
Sbjct: 583 GAILAGSRFDETVDRRMKFSARLGR 657
>03995
          Length = 944

 Score = 29.6 bits (65), Expect = 2.7,   Method: Compositional matrix adjust.
 Identities = 12/25 (48%), Positives = 19/25 (76%)
 Frame = +3

Query: 59  GWLLDGTKFDSSLDRKDKFSFDLGK 83
           G +L G++FD ++DR+ KFS  LG+
Sbjct: 573 GAILAGSRFDETVDRRMKFSARLGR 647
>22027
          Length = 692

 Score = 28.1 bits (61), Expect = 8.5,   Method: Compositional matrix adjust.
 Identities = 12/40 (30%), Positives = 22/40 (55%)
 Frame = -3

Query: 265 EKLEQSNIVKERGTAYFKEGKYKQALLQYKKIVSWLEYES 304
           + +EQ+  ++  G  +FK GKY +AL  Y   V +  + +
Sbjct: 291 KSVEQAEALRTTGNEHFKCGKYDKALSCYNNAVRYAPHST 172
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|33469043|ref|NP_598770.1| nicalin homolog [Mus
musculus]
         (563 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

19056                                                                 219   2e-57
30901                                                                  30   2.0  
27942                                                                  28   7.0  
>19056
          Length = 627

 Score =  219 bits (559), Expect = 2e-57,   Method: Compositional matrix adjust.
 Identities = 114/211 (54%), Positives = 140/211 (66%)
 Frame = +2

Query: 309 LCLDTVGRGSHLRLHVSKPPREGTLQHAFLRELETVAAHQFPDVSFSMVHKKINLADDVL 368
           LCLD+VG G  L LHVSKPP+E +    F + LE  A  Q   V FSMVHKKINLADD+L
Sbjct: 2   LCLDSVGGGDSLHLHVSKPPKEDSSGGVFFKNLEAAAEGQDKPVQFSMVHKKINLADDML 181

Query: 369 AWEHERFAIRRLPAFTLSHLESHRAGPRSSIMDVRSRVDSKTLTRNTRIIAEALTRVIYN 428
           AWEHERF+I+RL AFT+SH    R   R+SI+D + +VD + L  N R+IAE L R +YN
Sbjct: 182 AWEHERFSIKRLLAFTVSHFNVTRDLHRTSILDTQGQVDGEKLATNVRVIAEGLARHVYN 361

Query: 429 LTEKGTPPDMPVFTEQMQVQEEQIDSVMDWLTNQPRAAQLLDKDGTFLSTLEHFLSRYLK 488
           +T  G      +FT+ M  QEE   + +++LT QPRAAQL+  D T L TLE  LSRYLK
Sbjct: 362 ITHTGP---FSLFTDAMDTQEEAESAWLEFLTLQPRAAQLMPPDNTMLGTLETTLSRYLK 532

Query: 489 DVRQHHVKADKRDPEFVFYDQLKQVMNAYRV 519
           DVR+   KADKRDP+ VFY      MNA+ V
Sbjct: 533 DVRRTTFKADKRDPDVVFYTGAVYTMNAFNV 625
>30901
          Length = 518

 Score = 30.4 bits (67), Expect = 2.0,   Method: Composition-based stats.
 Identities = 27/94 (28%), Positives = 44/94 (46%), Gaps = 1/94 (1%)
 Frame = +1

Query: 325 SKPPREGTLQHAFLRELETVAAHQFPDVSFSMVHKKINLADDVLAWEHERFAIRRLPAFT 384
           ++P R   +QH   R+   VAA  +P + F++ H++   AD  L     ++ +R LP  +
Sbjct: 73  NQPLRCKKIQHFCRRQKSRVAAVWYPWIKFAVWHQQPIQADGTLHRLLLQWFLRSLPVGS 252

Query: 385 LSHLESHRAGPRSSIMDVRSRV-DSKTLTRNTRI 417
               E     P   ++ VR RV D    TR  R+
Sbjct: 253 SPDPEEVTCLP---VLRVRGRVGDGSDGTRVVRL 345
>27942
          Length = 937

 Score = 28.5 bits (62), Expect = 7.0,   Method: Compositional matrix adjust.
 Identities = 26/71 (36%), Positives = 34/71 (47%), Gaps = 3/71 (4%)
 Frame = -1

Query: 242 GSGISVLLELARLFSRLYTYKRTHAAYNLLFFAS--GGGKFN-YQGTKRWLEDSLDHTDS 298
           GSG+S   E  RL       + T  ++ L F AS   G KF  ++GT  W+  S    DS
Sbjct: 688 GSGLSR*QEADRL------TRTTSGSFRLSFQASPNCGDKFKLFRGT--WISQSTSPRDS 533

Query: 299 SLLQDNVAFVL 309
           S L DN+   L
Sbjct: 532 SNLNDNMGNTL 500
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|38198665|ref|NP_938085.1| p47 protein [Mus musculus]
         (372 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

20184                                                                 218   2e-57
37511                                                                  42   3e-04
19203                                                                  31   0.65 
01024                                                                  29   2.7  
13473                                                                  28   7.7  
>20184
          Length = 867

 Score =  218 bits (556), Expect = 2e-57,   Method: Compositional matrix adjust.
 Identities = 111/190 (58%), Positives = 138/190 (72%)
 Frame = +1

Query: 182 VHVVLKLWKTGFSLDNGDLRSYQDPSNAQFLESIRRGEVPAELRRLAHGGQVNLDMEDHR 241
           V V LK+WK GFS+++GDLRSY DP N +FLESIRRGEVP EL R A GG+VNL MEDH 
Sbjct: 28  VDVTLKMWKKGFSINSGDLRSYDDPVNKEFLESIRRGEVPQELIREARGGEVNLSMEDHH 207

Query: 242 DEDFVKPKGAFKAFTGEGQKLGSTAPQVLNTSSPAQQAENEAKASSSILINEAEPTTNIQ 301
            EDFV+ + A KAF+GEG  LGS AP V++T+S +  +   A ++  + ++ ++P T IQ
Sbjct: 208 SEDFVQSRAALKAFSGEGHMLGSPAPAVVSTAS-SGASSASAASAPKVQVDSSKPLTTIQ 384

Query: 302 IRLADGGRLVQKFNHSHRISDIRLFIVDARPAMAATSFVLMTTFPNKELADENQTLKEAN 361
           IRLADG R+V KFN SH + DIR  I+      A  +FVLMTTFPNKEL+DE QTL +A 
Sbjct: 385 IRLADGQRVVAKFNLSHTVRDIRNHIIACHSQYAGATFVLMTTFPNKELSDETQTLDQAK 564

Query: 362 LLNAVIVQRL 371
           L NAVIVQRL
Sbjct: 565 LANAVIVQRL 594
>37511
          Length = 635

 Score = 42.4 bits (98), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 20/26 (76%), Positives = 22/26 (84%)
 Frame = +2

Query: 346 PNKELADENQTLKEANLLNAVIVQRL 371
           PNKEL+DE QTL +A L NAVIVQRL
Sbjct: 2   PNKELSDETQTLDQAKLANAVIVQRL 79
>19203
          Length = 450

 Score = 31.2 bits (69), Expect = 0.65,   Method: Compositional matrix adjust.
 Identities = 20/73 (27%), Positives = 35/73 (47%), Gaps = 2/73 (2%)
 Frame = +3

Query: 292 NEAEPTTNIQIRLADGGRLVQKFNHSHRISDIRLFIVDARPAMAATSFVLMTTFPNKELA 351
           + A+P TN+ IR  DG +       S ++    LF+  +    A  ++ L+  FP + L+
Sbjct: 87  DTADPITNLVIRFPDGKKEQLSLPCSSKLQ--ALFVFCSSKGFAQENYELVVNFPRRTLS 260

Query: 352 --DENQTLKEANL 362
             D   T+ +A L
Sbjct: 261 SLDPGSTITDAQL 299
>01024
          Length = 1679

 Score = 29.3 bits (64), Expect = 2.7,   Method: Compositional matrix adjust.
 Identities = 20/51 (39%), Positives = 26/51 (50%), Gaps = 2/51 (3%)
 Frame = -2

Query: 11   EFVAVTGTEEDRA--RFFLESAGWDLQIALASFYEDGGDEDIVTISQATPS 59
            EF    G  E  +  RFFL  AG    + LASF+ D   ED+V +S +  S
Sbjct: 1375 EFPLTVGVAESSSVLRFFLSGAGEAEDLRLASFFLDFVSEDLVVLSFSLFS 1223
>13473
          Length = 528

 Score = 27.7 bits (60), Expect = 7.7,   Method: Compositional matrix adjust.
 Identities = 26/105 (24%), Positives = 45/105 (42%)
 Frame = -2

Query: 116 SPNELVDDLFKGAKEHGAVAVERVTKSPGETSKPRPFAGGGYRLGAAPEEESAYVAGERR 175
           SP +  DD+    K    +AVE     P  T KP+P A   Y + A   + S      + 
Sbjct: 341 SPTQEQDDMLSKRK----LAVEYAKNVPKPTVKPKPTAFNSYEVAA---KLSPIAKTSKG 183

Query: 176 RHSGQDVHVVLKLWKTGFSLDNGDLRSYQDPSNAQFLESIRRGEV 220
             +G++  V +      F L+    R  +D ++A+ ++   +G V
Sbjct: 182 GEAGKEASVKV------FDLEKLHKRHQEDKTSAKLIQQKAQGLV 66
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|86990458|ref|NP_032467.2| kinesin family member 1B
isoform a [Mus musculus]
         (1150 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

33215                                                                 220   2e-57
38050                                                                 104   2e-56
12048                                                                 149   2e-40
28434                                                                 135   1e-31
11818                                                                 110   1e-31
13148                                                                 124   2e-28
02896                                                                 114   3e-25
34477                                                                 108   9e-24
15043                                                                 103   6e-22
34899                                                                  96   7e-20
14618                                                                  94   3e-19
17748                                                                  65   1e-10
36593                                                                  48   2e-05
38061                                                                  42   0.001
37184                                                                  34   0.37 
26335                                                                  31   3.2  
04556                                                                  31   3.3  
>33215
          Length = 696

 Score =  220 bits (561), Expect = 2e-57,   Method: Compositional matrix adjust.
 Identities = 120/238 (50%), Positives = 156/238 (65%), Gaps = 2/238 (0%)
 Frame = +1

Query: 146 YMEIYCERVRDLLNPKNKGNLRVREHPLLGPYVEDLSKLAVTSYTDIADLMDAGNKARTV 205
           Y+EIY E +RDLL+      L ++  P  G YV+DLS     S  +I  +M+ GN+ R+V
Sbjct: 1   YLEIYQEEIRDLLSKDQSKRLELKXRPDTGVYVKDLSSFVTKSVREIEHVMNVGNQNRSV 180

Query: 206 AATNMNETSSRSHAVFTIVF--TQKKQDPETNLSTEKVSKISLVDLAGSERADSTGAKGT 263
            ATNMNE SSRSHA+F I    ++   D E ++   +V K+++VDLAGSER   TGA G 
Sbjct: 181 GATNMNEHSSRSHAIFIITVECSEIGADGENHI---RVGKLNMVDLAGSERQAKTGATGD 351

Query: 264 RLKEGANINKSLTTLGKVISALAEVSKKKKKTDFIPYRDSVLTWLLRENLGGNSRTAMVA 323
           RLKE   IN SL+ L  VISAL +      KT  IPYRDS LT LL+++LGGNS+T MVA
Sbjct: 352 RLKEATKINLSLSALSNVISALVDA-----KTTHIPYRDSKLTRLLQDSLGGNSKTTMVA 516

Query: 324 ALSPADINYDETLSTLRYADRAKQIKCNAVINEDPNAKLVRELKEEVTRLKDLLRAQG 381
            + PA  N+DETL+TLRYA+RAK IK    INEDP   L+RE ++E+ RLK+ L  +G
Sbjct: 517 NIGPASYNFDETLTTLRYANRAKSIKNKPKINEDPKDALLREFQDEINRLKNQLSEKG 690
>38050
          Length = 809

 Score =  104 bits (259), Expect(3) = 2e-56,   Method: Compositional matrix adjust.
 Identities = 59/109 (54%), Positives = 72/109 (66%)
 Frame = -2

Query: 160 PKNKGNLRVREHPLLGPYVEDLSKLAVTSYTDIADLMDAGNKARTVAATNMNETSSRSHA 219
           PK KG LR+R+HP  G Y + L  + V SY DI   M+AG   RTVAATNMN TSSR+H 
Sbjct: 748 PK-KGGLRIRQHPKNGFYADGLQVVPVVSYEDIEKKMEAGTTNRTVAATNMNATSSRAHT 572

Query: 220 VFTIVFTQKKQDPETNLSTEKVSKISLVDLAGSERADSTGAKGTRLKEG 268
           +  I F QK ++      T K + I+LVDLAGSERADSTGA GT  ++G
Sbjct: 571 IVGITFMQKFKNAAGE-ETTKSALINLVDLAGSERADSTGATGTD*RKG 428

 Score = 98.2 bits (243), Expect(3) = 2e-56,   Method: Compositional matrix adjust.
 Identities = 47/64 (73%), Positives = 55/64 (85%)
 Frame = -3

Query: 314 GGNSRTAMVAALSPADINYDETLSTLRYADRAKQIKCNAVINEDPNAKLVRELKEEVTRL 373
           G NS+T MVAALSPADINY+ETLSTLRYADRAKQIK  A++NEDP  KL+REL+EE  +L
Sbjct: 300 GWNSKTIMVAALSPADINYEETLSTLRYADRAKQIKTKAMVNEDPTDKLIRELQEENDKL 121

Query: 374 KDLL 377
           K +L
Sbjct: 120 KAML 109

 Score = 57.4 bits (137), Expect(3) = 2e-56,   Method: Composition-based stats.
 Identities = 32/57 (56%), Positives = 39/57 (68%)
 Frame = -1

Query: 262 GTRLKEGANINKSLTTLGKVISALAEVSKKKKKTDFIPYRDSVLTWLLRENLGGNSR 318
           G RLKEGA IN+SL+ LG  ISALA+  K   K   +P+RDS LT LL+  LGG +R
Sbjct: 449 GDRLKEGAAINQSLSCLGNCISALAD--KAGGKNVKVPFRDSALTKLLKNALGGTAR 285
>12048
          Length = 1162

 Score =  149 bits (376), Expect(2) = 2e-40,   Method: Compositional matrix adjust.
 Identities = 97/258 (37%), Positives = 144/258 (55%), Gaps = 8/258 (3%)
 Frame = +2

Query: 100 GAGKSYTMMGKQEESQA-GIIPQLCEELFEKINDNCNEEMSYSVEVSYMEIYCERVRDLL 158
           G GK++T+ G  E     G+IP+    ++E+   N   E+S++V +SY+EIY +   DLL
Sbjct: 410 GGGKTFTITGGAERYMDRGLIPRSLSYIYEQTEKN--PELSFTVHISYLEIYNDSGYDLL 583

Query: 159 NPKNKG-------NLRVREHPLLGPYVEDLSKLAVTSYTDIADLMDAGNKARTVAATNMN 211
           +PK++         + + E      ++ +LS     S  +  +L+  G+  R +A T MN
Sbjct: 584 DPKHEAAKLEDLPKVNLLEDSDQNIHLRNLSVHQANSEEEALNLLFLGDTNRMIAETPMN 763

Query: 212 ETSSRSHAVFTIVFTQKKQDPETNLSTEKVSKISLVDLAGSERADSTGAKGTRLKEGANI 271
           + SSRSH +FTI  T +    ET  +T + +K  LVDLAGSER   T   G  L E   I
Sbjct: 764 QASSRSHCIFTIHITTR----ETGSATIRRAKYHLVDLAGSERVAKTNVNGQLLTEARYI 931

Query: 272 NKSLTTLGKVISALAEVSKKKKKTDFIPYRDSVLTWLLRENLGGNSRTAMVAALSPADIN 331
           N SL  L  VI AL+E S++      +PYR+S++T +LR++LGGN  T M+A  S    N
Sbjct: 932 NSSLHFLELVIIALSEKSRQH-----VPYRNSMMTSVLRDSLGGNCMTTMIATCSMEKRN 1096

Query: 332 YDETLSTLRYADRAKQIK 349
            DE++ST R+A R   IK
Sbjct: 1097MDESISTCRFAQRVAMIK 1150

 Score = 36.6 bits (83), Expect(2) = 2e-40,   Method: Composition-based stats.
 Identities = 13/32 (40%), Positives = 23/32 (71%)
 Frame = +1

Query: 69  SQNRVYNDIGKEMLLHAFEGYNVCIFAYGQTG 100
           +Q+ V+ ++ K ++ +  +GYN  +FAYGQTG
Sbjct: 316 NQDEVFQNVAKPVIDNVLQGYNGTVFAYGQTG 411
>28434
          Length = 777

 Score =  135 bits (339), Expect = 1e-31,   Method: Compositional matrix adjust.
 Identities = 73/127 (57%), Positives = 90/127 (70%)
 Frame = +2

Query: 248 DLAGSERADSTGAKGTRLKEGANINKSLTTLGKVISALAEVSKKKKKTDFIPYRDSVLTW 307
           DLAGSERA  T A+G R KEG NIN+ L  LG VISAL E  +K+     IPYRDS LT 
Sbjct: 62  DLAGSERAKRTRAEGDRFKEGVNINRGLLALGNVISALGEDVQKRG---HIPYRDSKLTR 232

Query: 308 LLRENLGGNSRTAMVAALSPADINYDETLSTLRYADRAKQIKCNAVINEDPNAKLVRELK 367
           LL+++LGGNS T MVA +SPAD N +ETL+TLRYADRA++IK   VIN DP +  +  L+
Sbjct: 233 LLQDSLGGNSHTLMVACVSPADSNMEETLNTLRYADRARKIKNKPVINRDPQSDEILRLR 412

Query: 368 EEVTRLK 374
           + V  L+
Sbjct: 413 QVVQSLQ 433
>11818
          Length = 657

 Score =  110 bits (275), Expect(2) = 1e-31,   Method: Compositional matrix adjust.
 Identities = 69/178 (38%), Positives = 103/178 (57%), Gaps = 7/178 (3%)
 Frame = -1

Query: 101 AGKSYTMMG------KQEESQAGIIPQLCEELFEKINDNCNEEMSYSVEVSYMEIYCERV 154
           +GK+YTM G        ++   GIIP++  +LF  I +    + ++ V VSY+EIY E +
Sbjct: 657 SGKTYTMGGCYDAALSHDDDLVGIIPRILGDLFNGIAER--SDYTFKVTVSYLEIYNEDL 484

Query: 155 RDLLN-PKNKGNLRVREHPLLGPYVEDLSKLAVTSYTDIADLMDAGNKARTVAATNMNET 213
            DLL  P  +  L +RE       ++ L ++ V S  D    +  G ++RT  AT MN+T
Sbjct: 483 LDLLCLPSQRQPLSIREEMNGEIKIKGLKEVEVGSLEDTLMCLSQGARSRTTGATAMNDT 304

Query: 214 SSRSHAVFTIVFTQKKQDPETNLSTEKVSKISLVDLAGSERADSTGAKGTRLKEGANI 271
           SSRSHA+FT+   + K++   +++   ++K  LVDLAGSERA  T A+G R KEG NI
Sbjct: 303 SSRSHAIFTVHIEKSKKE---DMNDHCIAKFHLVDLAGSERAKKTRAEGDRFKEGVNI 139

 Score = 45.4 bits (106), Expect(2) = 1e-31,   Method: Composition-based stats.
 Identities = 26/47 (55%), Positives = 32/47 (68%)
 Frame = -3

Query: 273 KSLTTLGKVISALAEVSKKKKKTDFIPYRDSVLTWLLRENLGGNSRT 319
           + L  LG VISAL E  +K+     IPYRDS LT LL+++LGGNS T
Sbjct: 136 RGLLALGNVISALGEDVQKRGH---IPYRDSKLTRLLQDSLGGNSHT 5
>13148
          Length = 653

 Score =  124 bits (312), Expect = 2e-28,   Method: Compositional matrix adjust.
 Identities = 76/190 (40%), Positives = 113/190 (59%), Gaps = 1/190 (0%)
 Frame = -3

Query: 86  FEGYNVCIFAYGQTGAGKSYTMMGK-QEESQAGIIPQLCEELFEKINDNCNEEMSYSVEV 144
            + ++ C+++  Q    K++TM G    ES  GIIP++ +++F  I    +E + + ++V
Sbjct: 543 LQWHHFCLWSNVQ---WKTHTMEGVLGNESLQGIIPRIVQDIFNYIY-GMDENLEFHIKV 376

Query: 145 SYMEIYCERVRDLLNPKNKGNLRVREHPLLGPYVEDLSKLAVTSYTDIADLMDAGNKART 204
           SY EIY +++RDLL+   K NL V E     PYV+  ++  V+S  ++ +++D G   R 
Sbjct: 375 SYFEIYMDKIRDLLDV-TKTNLSVHEDKNRVPYVKGCTERFVSSPEEVMEVVDEGKSNRH 199

Query: 205 VAATNMNETSSRSHAVFTIVFTQKKQDPETNLSTEKVSKISLVDLAGSERADSTGAKGTR 264
           VA TNMNE SSRSH+VF I   Q+  D E  L      K+ LVDLAGSE+   TGA+G  
Sbjct: 198 VAVTNMNEHSSRSHSVFLIHVKQENVDSEKKLH----GKLYLVDLAGSEKVSKTGAEGAV 31

Query: 265 LKEGANINKS 274
           L E  NIN+S
Sbjct: 30  LDEAKNINRS 1

 Score = 36.2 bits (82), Expect = 0.087,   Method: Composition-based stats.
 Identities = 16/35 (45%), Positives = 20/35 (57%)
 Frame = -1

Query: 69  SQNRVYNDIGKEMLLHAFEGYNVCIFAYGQTGAGK 103
           +Q  VY    K ++     GYN  IFAYGQT +GK
Sbjct: 602 TQEYVYTVTAKPIVADVLSGYNGTIFAYGQTSSGK 498
>02896
          Length = 2076

 Score =  114 bits (284), Expect = 3e-25,   Method: Compositional matrix adjust.
 Identities = 71/183 (38%), Positives = 108/183 (59%), Gaps = 2/183 (1%)
 Frame = +1

Query: 194 DLMDAGNKARTVAATNMNETSSRSHAVFTIVFTQKKQDPETNLSTEKVSKISLVDLAGSE 253
           +L+  G   R++AA ++N  SSRSH +FT+    + +   +   T  VSK++ VDLAGSE
Sbjct: 64  NLLFEGETNRSIAAHSLNRMSSRSHCIFTVYLESRSRVQSSAKYT--VSKLNFVDLAGSE 237

Query: 254 RADSTGAKGTRLKEGANINKSLTTLGKVISALAEVSKKKKKTDFIPYRDSVLTWLLRENL 313
           R   + ++G  + E   INKSL+ L +V+ ALA+     K  D IP+R S LT  L++++
Sbjct: 238 RIGKSKSEGKMVTEAMYINKSLSFLEQVVIALAD-----KNRDHIPFRQSKLTHYLKDSI 402

Query: 314 GGNSRTAMVAALSPADINYDETLSTLRYADRAKQIKCNAVINE--DPNAKLVRELKEEVT 371
           GGN  T ++A +       +ET+STLR+A R   +     INE  DP A LV++L+ E+ 
Sbjct: 403 GGNCNTVLIANVWGERAQLEETVSTLRFATRMMCVANEPAINEVYDP-ALLVKKLQREIN 579

Query: 372 RLK 374
            LK
Sbjct: 580 HLK 588
>34477
          Length = 811

 Score =  108 bits (271), Expect = 9e-24,   Method: Compositional matrix adjust.
 Identities = 69/147 (46%), Positives = 84/147 (57%), Gaps = 9/147 (6%)
 Frame = +3

Query: 240 KVSKISLVDLAGSERADSTGAKGTRLKEGANINKSLTTLGKVISALAEVSKKKKKTDFIP 299
           +V K+ LVDLAGSER   TGA G RLKE   IN SL+TLG VIS              +P
Sbjct: 189 RVGKLHLVDLAGSERQAKTGATGQRLKEATKINLSLSTLGNVIS--------------VP 326

Query: 300 YRDSVLTWLLRE--------NLGGNS-RTAMVAALSPADINYDETLSTLRYADRAKQIKC 350
                 T  L+E         L G   +T MVA + PAD NYDET+STLRYA+RAK IK 
Sbjct: 327 GGRQEHTHPLQELQAHSPAAGLPGRQLQTVMVANMGPADYNYDETISTLRYANRAKNIKN 506

Query: 351 NAVINEDPNAKLVRELKEEVTRLKDLL 377
            A INEDP   L+R+ ++E+  L+  L
Sbjct: 507 KAKINEDPKDALLRQFQKEIEELRKQL 587

 Score = 65.1 bits (157), Expect = 2e-10,   Method: Composition-based stats.
 Identities = 49/145 (33%), Positives = 72/145 (49%), Gaps = 3/145 (2%)
 Frame = +1

Query: 177 YVEDLSKLAVTSYTDIADLMDAGNKARTVAATNMNETSSRSHAVFTIVFTQKKQDPETNL 236
           YV+DLS   V +  D+  +M  GNK R+V +TNMN  SSRSHA+FT+             
Sbjct: 4   YVKDLSAFVVNNADDMDRIMTLGNKNRSVGSTNMNMHSSRSHAIFTVT---------VEC 156

Query: 237 STEKVSKISLVDLAGSERADSTGAKGTRLKE---GANINKSLTTLGKVISALAEVSKKKK 293
           S +  +  S+   A        G +    +E    A   +  +T    + A+   S    
Sbjct: 157 SEKGATGSSMYVWANCTWWTWXGQRDKPRQEPQASA*RKRPRSTCLCQLWAM*YRSLVDG 336

Query: 294 KTDFIPYRDSVLTWLLRENLGGNSR 318
           K+  IPYR+S LT LL+++LGGNS+
Sbjct: 337 KSTHIPYRNSKLTRLLQDSLGGNSK 411
>15043
          Length = 973

 Score =  103 bits (256), Expect = 6e-22,   Method: Compositional matrix adjust.
 Identities = 62/182 (34%), Positives = 103/182 (56%), Gaps = 1/182 (0%)
 Frame = +2

Query: 199 GNKARTVAATNMNETSSRSHAVFTIVFTQK-KQDPETNLSTEKVSKISLVDLAGSERADS 257
           G +AR + AT++    +R+HAVFTI   QK +Q  +  +     + I LV+LAG E AD+
Sbjct: 26  GRRARRMGATDIKAHRARAHAVFTITVEQKERQSSKVGVR----ANIMLVELAGCEAADA 193

Query: 258 TGAKGTRLKEGANINKSLTTLGKVISALAEVSKKKKKTDFIPYRDSVLTWLLRENLGGNS 317
           T  K     +G            V++ L  +   K+    +PYR+S++T LL++ LGGN+
Sbjct: 194 TDPKILAGTQG------------VVNVLKALGDSKQIGGHVPYRESLVTRLLQDTLGGNA 337

Query: 318 RTAMVAALSPADINYDETLSTLRYADRAKQIKCNAVINEDPNAKLVRELKEEVTRLKDLL 377
            T M+  +SP D +Y  T S L+Y   AK +K +A +N D    ++ E++++++RL+D +
Sbjct: 338 MTLMLVTVSPLDKSYQTTQSALQYGQFAKTVKNHARMNLDDTQDIIAEMRQDISRLRDKI 517

Query: 378 RA 379
            A
Sbjct: 518 AA 523
>34899
          Length = 564

 Score = 96.3 bits (238), Expect = 7e-20,   Method: Compositional matrix adjust.
 Identities = 52/153 (33%), Positives = 89/153 (58%)
 Frame = +3

Query: 68  ASQNRVYNDIGKEMLLHAFEGYNVCIFAYGQTGAGKSYTMMGKQEESQAGIIPQLCEELF 127
           A   ++Y +    M+  A EGYNV I A+G TG+GKS+ M G  +E   G+ P + ++LF
Sbjct: 30  AKNGQIYQEKCDSMVQRALEGYNVTIMAFGATGSGKSFLMNGNDQE--IGVAPMVIQQLF 203

Query: 128 EKINDNCNEEMSYSVEVSYMEIYCERVRDLLNPKNKGNLRVREHPLLGPYVEDLSKLAVT 187
           + +    N+E    V  S++EI  E++ DLLNP N+  + VR+H + G +V+ LS++   
Sbjct: 204 QHLRQRSNKE--SMVTASFVEILDEKMTDLLNPHNR-PMAVRQHVIKGIFVDGLSEMVAR 374

Query: 188 SYTDIADLMDAGNKARTVAATNMNETSSRSHAV 220
           +  +++ L + G +AR + AT++    +R  A 
Sbjct: 375 TGEELSQLYEQGRRARRMGATDIKAHRARYDAA 473
>14618
          Length = 724

 Score = 94.0 bits (232), Expect = 3e-19,   Method: Compositional matrix adjust.
 Identities = 70/235 (29%), Positives = 113/235 (48%), Gaps = 24/235 (10%)
 Frame = -2

Query: 4   ASVKVAVRVRPFNSRETSKESKCI------------------IQMQGNSTSIINPKNPKE 45
            +++V  RVRP    E +     I                   +M  N +++ N +    
Sbjct: 672 GNIRVFCRVRPLLGEEAATNDGVIHHINFPDSDNKVLELDRLTEMSMNESTLYNNRRGNN 493

Query: 46  APKSFSFDYSYWSHTSPEDPCFASQNRVYNDIGKEMLLHAFEGYNVCIFAYGQTGAGKSY 105
             + FSFD  +    + +D        V+ +I  +++  A +GYNVCIFAYGQTG+GK+Y
Sbjct: 492 KYE-FSFDRVFHPDNTQQD--------VFEEI-SQLVQSALDGYNVCIFAYGQTGSGKTY 343

Query: 106 TMMGK--QEESQAGIIPQLCEELFEKINDNCNEEMSYSVEVSYMEIYCERVRDLLNPKNK 163
           TM G    +E   G+IP+   ++F    +  ++   Y    S++EIY E + DLL+    
Sbjct: 342 TMEGGLVGDEDTKGMIPRAVSQIFSTARELQDKGWQYKFTTSFVEIYNEMIGDLLSSNKX 163

Query: 164 GNLRVREHPLLG----PYVEDLSKLAVTSYTDIADLMDAGNKARTVAATNMNETS 214
            N++  E  + G      V +L+ + VTS  +IA L+   ++ R VAAT  NE S
Sbjct: 162 KNVK-HEIRMAGRDNNVAVTNLTTVDVTSQHEIAKLLRQASENRAVAATKCNERS 1
>17748
          Length = 621

 Score = 65.1 bits (157), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 45/126 (35%), Positives = 71/126 (56%), Gaps = 7/126 (5%)
 Frame = -3

Query: 86  FEGYNVCIFAYGQTGAGKSYTMMG------KQEESQAGIIPQLCEELFEKINDNCNEEMS 139
           F+GYN  + AYGQTG+GK+++M G      K +E   GIIP++ ++LF  I +    + +
Sbjct: 373 FKGYNATVLAYGQTGSGKTFSMGGCYEASLKLDEEAMGIIPRIIKDLFNGIQE--RPDHT 200

Query: 140 YSVEVSYMEIYCERVRDLLNPKNKGN-LRVREHPLLGPYVEDLSKLAVTSYTDIADLMDA 198
           + V VSY+EIY E + BLL P ++   L +RE       ++ L ++ V S  D  D +  
Sbjct: 199 FKVTVSYLEIYNEELLBLLCPLSQRQPLTIREELNGEIKIKGLKEVTVGSVDDTLDCLSQ 20

Query: 199 GNKART 204
           G + RT
Sbjct: 19  GAQLRT 2
>36593
          Length = 466

 Score = 47.8 bits (112), Expect = 2e-05,   Method: Composition-based stats.
 Identities = 23/47 (48%), Positives = 34/47 (72%)
 Frame = +1

Query: 305 LTWLLRENLGGNSRTAMVAALSPADINYDETLSTLRYADRAKQIKCN 351
           LT+LL+ +LGGNS+T M   +SP + N+ ETL++LR+A +  Q  CN
Sbjct: 4   LTYLLQNSLGGNSKTLMFVNVSPKEENFSETLNSLRFATKVNQ--CN 138
>38061
          Length = 206

 Score = 42.0 bits (97), Expect = 0.001,   Method: Composition-based stats.
 Identities = 19/28 (67%), Positives = 25/28 (89%)
 Frame = -3

Query: 321 MVAALSPADINYDETLSTLRYADRAKQI 348
           +VA +SPAD N +ETL+TLRYADRA++I
Sbjct: 84  LVACVSPADSNMEETLNTLRYADRARKI 1
>37184
          Length = 420

 Score = 33.9 bits (76), Expect = 0.37,   Method: Compositional matrix adjust.
 Identities = 27/87 (31%), Positives = 39/87 (44%), Gaps = 5/87 (5%)
 Frame = +1

Query: 267 EGANINKSLTTLGKVISALA--EVSKKKKKTDFIPYRDSVLTWLL---RENLGGNSRTAM 321
           E  NIN SL TL  V+S  A    +K    T+      S     L   R    G  + AM
Sbjct: 7   EAGNINTSLLTLAAVLSCFATTNTTKTMSVTERTGSSHSGTAG*LDSSRIFFVGRGKAAM 186

Query: 322 VAALSPADINYDETLSTLRYADRAKQI 348
           +  +S     +DETL+  +++  AKQ+
Sbjct: 187 IVNVSQCASMFDETLNVFKFSAIAKQV 267
>26335
          Length = 1211

 Score = 30.8 bits (68), Expect = 3.2,   Method: Composition-based stats.
 Identities = 15/39 (38%), Positives = 21/39 (53%)
 Frame = +2

Query: 1030 VSKQHISNQQPPPQLRWRSNSLNNGQPKTTRCQATASSE 1068
            +S Q +S+Q PP   R     L + +P TT CQ   SS+
Sbjct: 332  LSVQMLSSQPPPQPQRKEQQPLKSIKPLTTMCQGMTSSQ 448
>04556
          Length = 1816

 Score = 30.8 bits (68), Expect = 3.3,   Method: Composition-based stats.
 Identities = 12/32 (37%), Positives = 16/32 (50%)
 Frame = +2

Query: 560  YVNGKRVAHPVQLRSGNRIIMGKNHVFRFNHP 591
            Y + KR   P Q+ S   ++  KNH F   HP
Sbjct: 1571 YYDSKRSVQPCQVVSNQMVLHSKNHYFHLLHP 1666
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|7305027|ref|NP_038537.1| enolase 2, gamma neuronal
[Mus musculus]
         (434 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

09637                                                                 218   3e-57
26158                                                                 135   3e-32
33905                                                                  58   7e-09
13259                                                                  30   2.7  
36511                                                                  28   4.9  
>09637
          Length = 1627

 Score =  218 bits (556), Expect = 3e-57,   Method: Compositional matrix adjust.
 Identities = 101/126 (80%), Positives = 113/126 (89%)
 Frame = +1

Query: 306 KFTANVGIQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQACKLAQENGW 365
           K T+    QIVGDDL VTNPKR++  +E+KACN LLLKVNQIGSVTEAI ACK++Q+ GW
Sbjct: 1   KMTSATDCQIVGDDLLVTNPKRVQTGIEKKACNALLLKVNQIGSVTEAIDACKMSQKEGW 180

Query: 366 GVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEELGDEARFAG 425
           GVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQL+RIEEELG +A++AG
Sbjct: 181 GVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLLRIEEELGGKAKYAG 360

Query: 426 HNFRNP 431
            NFRNP
Sbjct: 361 ENFRNP 378
>26158
          Length = 431

 Score =  135 bits (341), Expect = 3e-32,   Method: Compositional matrix adjust.
 Identities = 67/98 (68%), Positives = 79/98 (80%)
 Frame = -2

Query: 3   IEKIWAREILDSRGNPTVEVDLYTAKGLFRAAVPSGASTGIYEALELRDGDKQRYLGKGV 62
           I+KI AR+I DSRGNPTVEVDL T KGLFRAAVPSGASTGIYEA+ELRDGD + Y  KGV
Sbjct: 295 IKKIHARQIFDSRGNPTVEVDLTTDKGLFRAAVPSGASTGIYEAVELRDGDPKCYHKKGV 116

Query: 63  LKAVDHINSRIAPALISSGISVVEQEKLDNLMLELDGT 100
           L AV ++N +IA ALI SGI V  Q ++D  +++LDGT
Sbjct: 115 LTAVSNVNDKIAQALIESGIPVQNQREVDEFLMKLDGT 2
>33905
          Length = 560

 Score = 58.2 bits (139), Expect = 7e-09,   Method: Compositional matrix adjust.
 Identities = 29/73 (39%), Positives = 48/73 (65%), Gaps = 3/73 (4%)
 Frame = +2

Query: 361 QENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEELGDE 420
           +E G  ++++  +GE++D FIADL V +    IK GAP R ER++K+N+L++IE EL   
Sbjct: 263 EEAGNQIILNACAGESQDDFIADLAVAMNVRFIKIGAPNRGERISKFNRLLQIEAELEAS 442

Query: 421 ARFAG---HNFRN 430
           ++ A    H F++
Sbjct: 443 SKLAPQVDHEFKH 481
>13259
          Length = 1751

 Score = 29.6 bits (65), Expect = 2.7,   Method: Compositional matrix adjust.
 Identities = 16/67 (23%), Positives = 33/67 (49%), Gaps = 1/67 (1%)
 Frame = +2

Query: 5   KIWAREILDSRGNPTVEVDLYTAKGLFRAAVPSGASTGIYEALELRDGDKQRYLGKGV-L 63
           K+W +  ++    PT E++     G+F A +    +  +    ++ D D+ RY  +G+  
Sbjct: 392 KVWIQACINEDLPPTTELEEGLRNGVFLAKLGHFFAAXVVSLKKIYDKDQTRYKSRGLHF 571

Query: 64  KAVDHIN 70
           +  D+IN
Sbjct: 572 RHTDNIN 592
>36511
          Length = 169

 Score = 28.5 bits (62), Expect = 4.9,   Method: Composition-based stats.
 Identities = 13/34 (38%), Positives = 22/34 (64%)
 Frame = -2

Query: 137 LAGNSDLILPVPAFNVINGGSHAGNKLAMQEFMI 170
           L  N ++ILP+ A NV N G++   +L+  +FM+
Sbjct: 114 LKDNINIILPITAHNVANIGNNPMKELS*TQFMV 13
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|75992913|ref|NP_001028769.1| acyl-CoA synthetase
long-chain family member 6 isoform 2 [Mus musculus]
         (722 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

03756                                                                 219   4e-57
34113                                                                 161   1e-39
02291                                                                 135   6e-32
21564                                                                 133   3e-31
14024                                                                  91   2e-18
20450                                                                  84   2e-16
26510                                                                  61   2e-09
37217                                                                  55   7e-08
00262                                                                  42   0.001
13327                                                                  39   0.007
19187                                                                  37   0.025
11241                                                                  35   0.13 
22123                                                                  34   0.20 
02723                                                                  30   2.3  
21989                                                                  30   3.7  
25119                                                                  29   6.8  
>03756
          Length = 992

 Score =  219 bits (557), Expect = 4e-57,   Method: Compositional matrix adjust.
 Identities = 110/259 (42%), Positives = 163/259 (62%), Gaps = 3/259 (1%)
 Frame = +2

Query: 68  WLTHRPKALQPPCNLLKQSEEVEDGGGARRS-VIGGCTQLLTHYYDDARTMYQVFRRGLS 126
           +L+ RP+ + PP +L  QS  V++   +R S ++    +L+T+ YDDA+T Y+ F RGL 
Sbjct: 44  YLSARPQPVVPPVHLHNQSVMVDEKERSRASCLLANPKELMTYLYDDAKTTYEAFLRGLR 223

Query: 127 ISGNGPCLGFRK-PEQPYQWLSYQEVAKRAEFLGSGLLQHDCKVGTEQFVGVFAQNRPEW 185
           +S NG CLG+R  P QP+ W+SY++V  RA   GSGL+    +     FVG+++ N  EW
Sbjct: 224 VSNNGSCLGWRSGPGQPFSWMSYRQVLDRAHCFGSGLISKGVQPSNSSFVGIYSGNCVEW 403

Query: 186 IIAELACYTYSMVVVPLYDTLGPGSISYIINTADICTVIVDKPHKATLLLEHVERKETPG 245
            +A+L C+ YSMV VPLYDTLGP +  YIIN   +CTV+ D  +KA  LLE  +  + P 
Sbjct: 404 SLADLGCHMYSMVPVPLYDTLGPQACVYIINQTKLCTVVCDDVNKAKRLLEIAD--QVPS 577

Query: 246 LKLVILM-EPFEDALRERGKKCGVDIKSMQAIEDCGRENHHAPVPPRPDDLSIVCFTSGT 304
           LK  I   + +   +R+   +  V++ + + IE  G ++   P+PP+PDDL+ +C+TSGT
Sbjct: 578 LKRFIFTGKTWPQDIRDLANERKVELLTFKEIESIGTKDTRDPIPPKPDDLATLCYTSGT 757

Query: 305 TGNPKGAMLTHGNVVADFS 323
           TG+PKG MLTH N +   S
Sbjct: 758 TGDPKGVMLTHANFLIMLS 814
>34113
          Length = 694

 Score =  161 bits (407), Expect = 1e-39,   Method: Compositional matrix adjust.
 Identities = 76/166 (45%), Positives = 108/166 (65%)
 Frame = -3

Query: 158 LGSGLLQHDCKVGTEQFVGVFAQNRPEWIIAELACYTYSMVVVPLYDTLGPGSISYIINT 217
            GSGL     K G +   G+F QN  EW+IA+ AC  YSMV V LYDTLG  ++ Y++N 
Sbjct: 560 FGSGLFALGVKPGQDTNFGIFTQNSSEWVIADQACQMYSMVTVALYDTLGVEAVKYVVNL 381

Query: 218 ADICTVIVDKPHKATLLLEHVERKETPGLKLVILMEPFEDALRERGKKCGVDIKSMQAIE 277
           A+I TV+ DK  +A +LLE   + E P LKL+++ E   + L+++ ++ GV I     +E
Sbjct: 380 AEIGTVVCDKEVRAKILLEG--KSELPCLKLIVMXEEITEELQQKAQRAGVKIIRFSEVE 207

Query: 278 DCGRENHHAPVPPRPDDLSIVCFTSGTTGNPKGAMLTHGNVVADFS 323
           D G++N   P+ P+P D+  +CFTSGTTGNPKG +LTH N+VA+ S
Sbjct: 206 DLGKKNIREPLLPKPSDVCTICFTSGTTGNPKGVVLTHANLVANVS 69
>02291
          Length = 3161

 Score =  135 bits (340), Expect = 6e-32,   Method: Compositional matrix adjust.
 Identities = 124/447 (27%), Positives = 200/447 (44%), Gaps = 21/447 (4%)
 Frame = -1

Query: 191  ACYTYSMVVVPLYDTLGPGSISYIINTADICTVIVDKPHKATLLLEHVERKETPGLKLVI 250
             C     +   +Y T  P +  ++  ++    ++ +   +   +L+   R   P LK ++
Sbjct: 3161 GCIYAGGLATGIYTTNSPEACEFVAASSQANVIVAENSQQLKKILQ--VRHNLPHLKAIV 2988

Query: 251  LMEPFEDALRERGKKCGVDIKSMQAIEDCGRENHHAPVPPR-----PDDLSIVCFTSGTT 305
                  D    +      D+ S +     G +   + +  R     P+   ++ +TSGTT
Sbjct: 2987 QYTGQVDEAHAK------DVLSWEQFMKAGDDVPDSVLDERIKALSPNKCCVLIYTSGTT 2826

Query: 306  GNPKGAMLTHGN----VVADFSGFLKVTESQWAPTCADVHFSYLPLAHMFERMVQSVVYC 361
            G PKG ML+H N    V  + S  ++   +++         SYLPL+H+  +M+   V  
Sbjct: 2825 GTPKGVMLSHDNITYTVAVNMSSTMQQLNTKFGQQSG---ISYLPLSHIAAQMMDIYVXI 2655

Query: 362  -HGGRVGFFQGDI--RLLSDDMKALRPTIFPVVPRLLNRMYDKIFHQAD--TSLKRWLLE 416
              GG   F Q D     L   ++ +RP IF  VPR+  +M + +   A   T +K+ +  
Sbjct: 2654 GFGGTTYFAQPDALKGSLGATLREVRPHIFLGVPRVWEKMQETMQTAARSVTGMKKKIGA 2475

Query: 417  FAAKRKQAEVRSGIIRNNS------IWDELFFNKIQASLG-GHVRMIVTGAAPASPTVLG 469
            +A K    +    I+   S      + + L F K++  LG     M ++GAAP +   L 
Sbjct: 2474 WA-KGVGLKANYAIMEGRSPPAXXPLANALVFKKVRGLLGLDRCLMQLSGAAPIAKETLE 2298

Query: 470  FLRAALGCQVYEGYGQTECTAGCTFTTPGDWTSGHVGAPLPCNHIKLVDAEELNYWTCKG 529
            +   +L   + E YG +EC+   T   P       VG  L     +L + +E       G
Sbjct: 2297 YF-MSLNVPICEVYGMSECSGPHTVGFPKVNRVNSVGRELNGCTTELANQDE------DG 2139

Query: 530  EGEICVKGPNVFKGYLKDEDRTKEALDSDGWLHTGDIGKWLPEGTLKIIDRKKHIFKLAQ 589
             GE+ + G +VF GYL DE++TKEALD  G LH+GD+GK   +G L I  R K +   A 
Sbjct: 2138 NGEVVMHGRHVFMGYLNDEEKTKEALDDAGGLHSGDVGKKDKDGFLFITGRIKELIITAG 1959

Query: 590  GEYVAPEKIENIYIRSEPVAQIYVHGD 616
            GE + P  IE+    + PV Q  VH D
Sbjct: 1958 GENIPPVAIEDRVKEALPVGQP-VHAD 1881

 Score = 31.2 bits (69), Expect = 1.7,   Method: Compositional matrix adjust.
 Identities = 12/31 (38%), Positives = 19/31 (61%)
 Frame = -2

Query: 688  FSVQNGLLTPTLKAKRPELREYFKKQIEELY 718
            FS+  G L PT+K +RP + + + K I+  Y
Sbjct: 1615 FSIPGGELGPTMKMRRPIIHKMYTKTIDAFY 1523
>21564
          Length = 509

 Score =  133 bits (334), Expect = 3e-31,   Method: Compositional matrix adjust.
 Identities = 64/170 (37%), Positives = 105/170 (61%), Gaps = 1/170 (0%)
 Frame = +1

Query: 118 YQVFRRGLSISGNGPCLGFR-KPEQPYQWLSYQEVAKRAEFLGSGLLQHDCKVGTEQFVG 176
           Y+ F RG  +S NG CLG++  P +PY+W++Y E+ +RAE++G+GL+           VG
Sbjct: 1   YEGFLRGARVSNNGRCLGYKPSPTEPYRWITYNELLQRAEYIGAGLIALGLSPQNTTRVG 180

Query: 177 VFAQNRPEWIIAELACYTYSMVVVPLYDTLGPGSISYIINTADICTVIVDKPHKATLLLE 236
           V++QNRPE++I +   + YSMV VPLYDTLG  + ++I+N A+I  V+ D   K   +L+
Sbjct: 181 VYSQNRPEYVITDCGLWAYSMVGVPLYDTLGAEACNHILNQAEIKVVVCDTNVKVKNMLQ 360

Query: 237 HVERKETPGLKLVILMEPFEDALRERGKKCGVDIKSMQAIEDCGRENHHA 286
            +   ETP LK++++ME      R+   + GV +   + +E+ G+ +  A
Sbjct: 361 RL--SETPNLKILVVMEDITGESRQMADRAGVKLLQFKELEEMGKASPKA 504
>14024
          Length = 655

 Score = 90.9 bits (224), Expect = 2e-18,   Method: Compositional matrix adjust.
 Identities = 56/188 (29%), Positives = 102/188 (54%), Gaps = 3/188 (1%)
 Frame = +3

Query: 443 NKIQASLG-GHVRMIVTGAAPASPTVLGFLRAALGCQVYEGYGQTECTAGC-TFTTPGDW 500
           +K++A+LG   V  +V+ AAP SP    +   +L  ++ + +G +E T+GC T   P   
Sbjct: 3   SKVRAALGFDRVISLVSAAAPMSPETKKYF-LSLDMKILDAFGMSE-TSGCHTLCQPDST 176

Query: 501 TSGHVGAPLPCNHIKLVDAEELNYWTCKGEGEICVKGPNVFKGYLKDEDRTKEALDSDGW 560
               +G  LP    K+++ +        G GE+C++G +VF GY+ ++++T+E+LD D W
Sbjct: 177 LLNSIGKSLPGCESKIINQD------ANGHGELCIRGRHVFMGYISNKEKTEESLDDDCW 338

Query: 561 LHTGDIGKWLPEGTLKIIDRKKHIFKLAQGEYVAPEKIENIYIRS-EPVAQIYVHGDSLK 619
           LH+GD+     +G + +  R K +   A GE + P  IENI  +  + ++  ++ G+  K
Sbjct: 339 LHSGDLAYIDDKGYVCLTGRLKELIITAGGENIPPVHIENIIKKELDGISNAFLVGEQRK 518

Query: 620 AFLVGIVV 627
              V + +
Sbjct: 519 YLTVLVSI 542
>20450
          Length = 775

 Score = 84.0 bits (206), Expect = 2e-16,   Method: Compositional matrix adjust.
 Identities = 42/123 (34%), Positives = 68/123 (55%)
 Frame = -3

Query: 493 TFTTPGDWTSGHVGAPLPCNHIKLVDAEELNYWTCKGEGEICVKGPNVFKGYLKDEDRTK 552
           TF+TP  +  G  G P P    K++D+E          G++  +GP + +GY K+   T 
Sbjct: 665 TFSTPAKYELGSCGFPTPNAEFKVIDSETGKCLGVNQAGDLYKRGPLIMRGYHKNPQATA 486

Query: 553 EALDSDGWLHTGDIGKWLPEGTLKIIDRKKHIFKLAQGEYVAPEKIENIYIRSEPVAQIY 612
           + +D+ GWL TGD+G++   G L I+DRKK + K  +GE VAP  +E++ +    ++   
Sbjct: 485 DTIDAQGWLKTGDVGQFDSNGFLYIVDRKKELIKY-KGEQVAPAMLEDVLLSHPGISDAA 309

Query: 613 VHG 615
           V G
Sbjct: 308 VIG 300
>26510
          Length = 1692

 Score = 61.2 bits (147), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 32/80 (40%), Positives = 47/80 (58%)
 Frame = +2

Query: 531  GEICVKGPNVFKGYLKDEDRTKEALDSDGWLHTGDIGKWLPEGTLKIIDRKKHIFKLAQG 590
            GE C+ GP    GYL ++  T + +D DGWLHTGD+G    +G + I DR K + K  +G
Sbjct: 1277 GEYCMDGPQKMLGYLHNQQATDDMIDRDGWLHTGDLGYMREDGMIIIEDRLKELIKY-KG 1453

Query: 591  EYVAPEKIENIYIRSEPVAQ 610
              V P ++E++ + S P  Q
Sbjct: 1454 FQVPPAELESLLL-SHPAVQ 1510

 Score = 43.5 bits (101), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 43/172 (25%), Positives = 68/172 (39%), Gaps = 1/172 (0%)
 Frame = +1

Query: 181 NRPEWIIAELACYTYSMVVVPLYDTLGPGSISYIINTADICTVIVDKPHKATLLLEHVER 240
           N PE+ I  LA     ++V P   T  P  +S+++     C +    P    L+   +  
Sbjct: 391 NLPEFSILILAAAYLGVIVSPANPTYTPAELSHMLTHNGACAMFT-IPQLVPLVQAAIAD 567

Query: 241 KETP-GLKLVILMEPFEDALRERGKKCGVDIKSMQAIEDCGRENHHAPVPPRPDDLSIVC 299
            + P  +K V      E+           D KS     D               D+  + 
Sbjct: 568 PDLPHSVKEVYTFGHAEEGTEFFQALMSDDGKSFPDNIDINPST----------DVLFLP 717

Query: 300 FTSGTTGNPKGAMLTHGNVVADFSGFLKVTESQWAPTCADVHFSYLPLAHMF 351
           ++SGTTG PKG ML+H N+VA+   F ++  +Q      D     LP  H++
Sbjct: 718 YSSGTTGLPKGVMLSHRNIVANILQFRELANTQP----EDRTLGLLPFFHIY 861
>37217
          Length = 548

 Score = 55.5 bits (132), Expect = 7e-08,   Method: Compositional matrix adjust.
 Identities = 34/111 (30%), Positives = 53/111 (47%), Gaps = 1/111 (0%)
 Frame = -2

Query: 455 MIVTGAAPASPTVLGFLRAALGCQ-VYEGYGQTECTAGCTFTTPGDWTSGHVGAPLPCNH 513
           +++ GAAP S      ++  LG   + +GYG +E T             G V       +
Sbjct: 331 VLLCGAAPLSRETEDQIKERLGIPFIRQGYGLSESTLSVLVQNDEHCKPGSVXVLNVGVY 152

Query: 514 IKLVDAEELNYWTCKGEGEICVKGPNVFKGYLKDEDRTKEALDSDGWLHTG 564
            K++D +   +      GE+C KGP + KGY+ D+  T+  +  DGWLHTG
Sbjct: 151 AKVIDPDTGKHLGANERGELCFKGPGIMKGYIGDKRSTQTTI-KDGWLHTG 2
>00262
          Length = 1036

 Score = 41.6 bits (96), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 31/120 (25%), Positives = 53/120 (44%), Gaps = 1/120 (0%)
 Frame = -1

Query: 495  TTPGDWTSGHVGAPLPCNHIKLVDAEELNYWTCKGEGEICVKGPNVFKGYLKDEDRTKEA 554
            T P  +  G  G       +++VD E L        GEI  K P ++  Y+ +++  K++
Sbjct: 1015 TKPDTYQDGMTGPAAVGVQVRIVD-EHLQDVGEGQTGEIIAKSPALYSRYIDNDEAAKKS 839

Query: 555  LDSDGWLHTGDIGKWLPEGTLKIIDRKKHIFKLAQGEYVA-PEKIENIYIRSEPVAQIYV 613
               DGW  T D+G +  +    II   +    + +G Y+  P  +E +  RS  V  + V
Sbjct: 838  FTPDGWFRTDDMGCFNQDK--HIIHLGRRTDAITRGAYLCYPGWLETLLRRSPSVRDVCV 665
>13327
          Length = 549

 Score = 38.9 bits (89), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 19/56 (33%), Positives = 32/56 (57%)
 Frame = +3

Query: 560 WLHTGDIGKWLPEGTLKIIDRKKHIFKLAQGEYVAPEKIENIYIRSEPVAQIYVHG 615
           WL +GD+G +  +G L I+DRKK + K  + E V P  +E++ +    ++   V G
Sbjct: 3   WLDSGDVGYFDSDGFLYIVDRKKELIKF-KAEQVPPAMLEDVLLTHPGISDAAVIG 167
>19187
          Length = 742

 Score = 37.0 bits (84), Expect = 0.025,   Method: Compositional matrix adjust.
 Identities = 22/84 (26%), Positives = 40/84 (47%), Gaps = 1/84 (1%)
 Frame = +2

Query: 531 GEICVKGPNVFKGYLKDEDRTKEALDSDGWLHTGDIGKWLPEGTLKIIDRKKHIFKLAQG 590
           GEI  K P ++  Y+ +++  K++   DGW  T D+G +  +    II   +    + +G
Sbjct: 449 GEIIAKSPALYSRYIDNDEAAKKSFTPDGWFRTDDMGCFNQD--KHIIHLGRRTDAITRG 622

Query: 591 EYVA-PEKIENIYIRSEPVAQIYV 613
            Y+  P  +E +   S  V  + V
Sbjct: 623 AYLCYPGWLETLLRHSPSVRDVCV 694
>11241
          Length = 539

 Score = 34.7 bits (78), Expect = 0.13,   Method: Composition-based stats.
 Identities = 18/56 (32%), Positives = 30/56 (53%)
 Frame = +3

Query: 663 MVMLGKESGLHSFEQVKAIYIHCDMFSVQNGLLTPTLKAKRPELREYFKKQIEELY 718
           M + G++  + + ++V+   I    FS+  G L PTLK KR  + + +   IE LY
Sbjct: 48  MALSGQQQSISNAQKVQKFAIMPHDFSIVTGELGPTLKVKRNVVNKMYADLIETLY 215
>22123
          Length = 347

 Score = 34.3 bits (77), Expect = 0.20,   Method: Composition-based stats.
 Identities = 36/117 (30%), Positives = 49/117 (41%), Gaps = 11/117 (9%)
 Frame = +3

Query: 475 LGCQVYEGYGQTECTAGCTFTTPGDWTSGHVGAPLPCNHIKLVDAEELNYWTCKGEGEIC 534
            G +  +GYG TE     +  TP     G  G P P    K++D+E     T K     C
Sbjct: 33  FGVRCLQGYGMTEYPVA-SVATPAKNELGSCGFPTPNAEFKVIDSE-----TGK-----C 179

Query: 535 VKGPNVFKGYLKDEDRTKEAL--DSDGW---------LHTGDIGKWLPEGTLKIIDR 580
           + G N   G L+      E L  +S G          L TGD+G++   G L I+DR
Sbjct: 180 L-GVNQAGGSLQARTSHHERLPQESPGHRRHH*CSRVLKTGDVGQFDSNGFLYIVDR 347
>02723
          Length = 387

 Score = 30.4 bits (67), Expect = 2.3,   Method: Composition-based stats.
 Identities = 17/59 (28%), Positives = 25/59 (42%), Gaps = 3/59 (5%)
 Frame = +2

Query: 457 VTGAAPASPTVLGFLRAALGCQVYEGYGQTECTAGCTFTTPGD---WTSGHVGAPLPCN 512
           +  + PA+PT  G +        Y G+G T+ +   T  +P     W S H  AP   N
Sbjct: 32  IVNSTPAAPTTFGSVGNGTSGAGYLGWGGTQASDTSTTHSPSQMAGWGSTHTKAPTGWN 208
>21989
          Length = 452

 Score = 30.0 bits (66), Expect = 3.7,   Method: Composition-based stats.
 Identities = 18/46 (39%), Positives = 24/46 (52%), Gaps = 1/46 (2%)
 Frame = +3

Query: 317 NVVADFSGFLKVTESQWAPTCADVHFSYL-PLAHMFERMVQSVVYC 361
           +VV D    L+  E +W  TC D HF  L PL+   E ++Q   YC
Sbjct: 60  DVVYDLP--LRSLEEEWVKTCWDNHFLDLTPLSLGTENLLQESGYC 191
>25119
          Length = 604

 Score = 28.9 bits (63), Expect = 6.8,   Method: Composition-based stats.
 Identities = 11/14 (78%), Positives = 12/14 (85%)
 Frame = +2

Query: 159 GSGLLQHDCKVGTE 172
           GSGL+ H CKVGTE
Sbjct: 236 GSGLVTHSCKVGTE 277
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|94371710|ref|XP_989452.1| PREDICTED: unc-13 homolog B
isoform 2 [Mus musculus]
         (1591 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

30575                                                                 173   5e-57
11353                                                                  69   2e-11
22804                                                                  67   5e-11
25445                                                                  54   5e-07
19361                                                                  53   9e-07
13896                                                                  47   5e-05
29179                                                                  46   1e-04
35187                                                                  43   0.001
36305                                                                  40   0.007
30040                                                                  37   0.080
07591                                                                  33   0.69 
20879                                                                  31   3.9  
>30575
          Length = 456

 Score =  173 bits (439), Expect(2) = 5e-57,   Method: Compositional matrix adjust.
 Identities = 82/113 (72%), Positives = 96/113 (84%), Gaps = 4/113 (3%)
 Frame = +2

Query: 853 NFGKERFVKLLDQLHNSLRIDLSTYRNNFPAGSPERLQDLKSTVDLLTSITFFRMKVQEL 912
           NFGKE+FVKLLDQLHNSLRIDLS YRNNFPA  P R++DLKSTVD LTSITFFRMKVQEL
Sbjct: 2   NFGKEKFVKLLDQLHNSLRIDLSMYRNNFPASDPGRMKDLKSTVDFLTSITFFRMKVQEL 181

Query: 913 QSPPRASQVVKDCVKACLNSTYEYIFNNCHDLYSHQYQL---EQP-LEEPGPS 961
           QSPPRAS VVKDCV AC+ STY+++F NC++LY  ++Q    EQP +++ GPS
Sbjct: 182 QSPPRASTVVKDCVTACIRSTYKFLFENCYELYQREFQTDPSEQPAVDQEGPS 340

 Score = 68.2 bits (165), Expect(2) = 5e-57,   Method: Compositional matrix adjust.
 Identities = 30/36 (83%), Positives = 34/36 (94%)
 Frame = +3

Query: 964 NLDFWPKLITLIVSIIEEDKNSYTPVLSQFPQELNV 999
           +LDFW KLI L+VS+IEEDKNSYTPVLSQFPQ+LNV
Sbjct: 348 SLDFWHKLIVLVVSVIEEDKNSYTPVLSQFPQDLNV 455
>11353
          Length = 454

 Score = 68.9 bits (167), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 26/51 (50%), Positives = 34/51 (66%)
 Frame = +1

Query: 479 PHNFEVWSATTPTYCYECEGLLWGLARQGMRCSECGVKCHEKCQDLLNADC 529
           PH FE ++ TTPTYC  C+ LLWG ++ G  C +CG  CH+KCQ L+   C
Sbjct: 139 PHRFEKYTYTTPTYCDFCQQLLWGFSKTGTHCVDCGYNCHDKCQPLVPKTC 291
>22804
          Length = 967

 Score = 67.0 bits (162), Expect = 5e-11,   Method: Compositional matrix adjust.
 Identities = 26/51 (50%), Positives = 34/51 (66%)
 Frame = -3

Query: 479 PHNFEVWSATTPTYCYECEGLLWGLARQGMRCSECGVKCHEKCQDLLNADC 529
           PH FE ++ TTPTYC  C+ LLWG ++ G  C +CG  CH+KCQ L+   C
Sbjct: 833 PHRFEKYTYTTPTYCDFCQQLLWGFSKTGTHCVDCGYNCHDKCQPLVPKTC 681
>25445
          Length = 460

 Score = 53.9 bits (128), Expect = 5e-07,   Method: Composition-based stats.
 Identities = 18/46 (39%), Positives = 29/46 (63%)
 Frame = -1

Query: 477 TTPHNFEVWSATTPTYCYECEGLLWGLARQGMRCSECGVKCHEKCQ 522
           T  H F+  +  +PT+C  C  LL+GL  QG++C  C + CH++C+
Sbjct: 406 TNLHKFKAHTYGSPTFCDHCGSLLYGLIHQGLKCDSCDMNCHKRCE 269
>19361
          Length = 685

 Score = 53.1 bits (126), Expect = 9e-07,   Method: Compositional matrix adjust.
 Identities = 19/52 (36%), Positives = 32/52 (61%)
 Frame = -1

Query: 479 PHNFEVWSATTPTYCYECEGLLWGLARQGMRCSECGVKCHEKCQDLLNADCL 530
           PH F+V +     +C  C   +WGL  QG++C +CGV+ H+KC + +  +C+
Sbjct: 319 PHVFKVQNFNGLNWCELCANFMWGLIAQGVKCQDCGVQTHKKCSERMPNECM 164
>13896
          Length = 827

 Score = 47.4 bits (111), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 39/130 (30%), Positives = 62/130 (47%), Gaps = 3/130 (2%)
 Frame = +2

Query: 606 ITVVCAQGLQAKDKTGSSDPYVTVQVGKTKKRTKTIFGNLNPVWEEKFHFECHNSSDRIK 665
            TV+ A+ L +K K+G++D YVT+Q+GK K +T TI    NP W E+      +    I+
Sbjct: 164 FTVLRARNLISKGKSGNNDVYVTIQLGKEKYQTSTIRNAHNPEWFEECDLPIPHLHSEIE 343

Query: 666 VRVWDEDDDIKSRVKQRLKRESDDFLGQTII---EVRTLSGEMDVWYNLEKRTDKSAVSG 722
           V V+                 SDDFLG T +   E R        W +L+ + ++  +  
Sbjct: 344 VSVYHXG------------VLSDDFLGYTSLPLWEQRLEDTTKTQWISLKNKPNR-GLDN 484

Query: 723 AIRLQISVEI 732
             R +I V++
Sbjct: 485 KYRGEIEVKV 514
>29179
          Length = 1113

 Score = 46.2 bits (108), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 45/139 (32%), Positives = 63/139 (45%), Gaps = 9/139 (6%)
 Frame = -3

Query: 604 ITITVVCAQGLQAKDKTGSSDPYVTVQVGKTKKR---TKTIFGNLNPVWEEKFHFEC--H 658
           +T+ ++ A  L AKD TG+SDPYV + +   KK    TK    NLNP W E F FE   H
Sbjct: 493 LTLRIIRAVDLPAKDVTGTSDPYVKILLLPDKKHKLLTKVKKRNLNPHWNECFLFEGWPH 314

Query: 659 NS--SDRIKVRVWDEDDDIKSRVKQRLKRESDDFLGQTIIEVRT--LSGEMDVWYNLEKR 714
           N      + ++V D D         R  R  DD +G+T + +    LS     W  L+  
Sbjct: 313 NKLLEKTLYLQVIDYD---------RFSR--DDPIGETYLPLNEIDLSQSPVSWKYLQPC 167

Query: 715 TDKSAVSGAIRLQISVEIK 733
            D     G + L +  + K
Sbjct: 166 KDTRGKLGELLLSMCYQPK 110

 Score = 42.7 bits (99), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 31/107 (28%), Positives = 47/107 (43%), Gaps = 1/107 (0%)
 Frame = -3

Query: 1440 VTVKVVAANDLKWQ-TAGMFRPFVEVTMVGPHQSDKKRKFTTKSKSNNWTPKYNETFHFL 1498
            +T++++ A DL  +   G   P+V++ ++     DKK K  TK K  N  P +NE F F 
Sbjct: 493  LTLRIIRAVDLPAKDVTGTSDPYVKILLL----PDKKHKLLTKVKKRNLNPHWNECFLFE 326

Query: 1499 LGNEEGPEAYELQICVKDYCFAREDRVIGLAVMPLRDVAAKGSCACW 1545
                       L + V DY     D  IG   +PL ++    S   W
Sbjct: 325  GWPHNKLLEKTLYLQVIDYDRFSRDDPIGETYLPLNEIDLSQSPVSW 185

 Score = 35.8 bits (81), Expect = 0.13,   Method: Composition-based stats.
 Identities = 15/28 (53%), Positives = 22/28 (78%)
 Frame = -1

Query: 602 AKITITVVCAQGLQAKDKTGSSDPYVTV 629
            ++T+ V+ A+ L+AKD TGSSDPYV +
Sbjct: 105 GRLTVIVMKAKELKAKDITGSSDPYVKI 22
>35187
          Length = 593

 Score = 42.7 bits (99), Expect = 0.001,   Method: Composition-based stats.
 Identities = 17/50 (34%), Positives = 24/50 (48%)
 Frame = -3

Query: 480 HNFEVWSATTPTYCYECEGLLWGLARQGMRCSECGVKCHEKCQDLLNADC 529
           H F   +   PTYC+ C  +LWGL   G  C  C    H++C   + + C
Sbjct: 315 HFFTKKTFHKPTYCHHCTDILWGLIGVGYVCEVCNFVVHDRCMKTVVSPC 166
>36305
          Length = 586

 Score = 40.0 bits (92), Expect = 0.007,   Method: Composition-based stats.
 Identities = 27/82 (32%), Positives = 37/82 (45%), Gaps = 1/82 (1%)
 Frame = -1

Query: 621 GSSDPYVTVQVGKTKKRTKTIFGNLNPVWEEKFHFECHNSSDRI-KVRVWDEDDDIKSRV 679
           G SDPY  V VG    +TK I   + P W E F F       +I K+ + D+D   K   
Sbjct: 583 GKSDPYTVVTVGAQTFKTKVIDDTVEPRWNEVFEFVIDERDGQILKLNISDKDPGNK--- 413

Query: 680 KQRLKRESDDFLGQTIIEVRTL 701
                   DD LG T +++ T+
Sbjct: 412 --------DDPLGSTTMDISTI 371

 Score = 35.4 bits (80), Expect = 0.19,   Method: Compositional matrix adjust.
 Identities = 22/78 (28%), Positives = 38/78 (48%), Gaps = 2/78 (2%)
 Frame = -3

Query: 586 MKTVKQSVLDGTSKWSAKITITVVCAQGLQAKDKTG--SSDPYVTVQVGKTKKRTKTIFG 643
           M+ V+   +D  S  +A + + +  A  L  +DK       PYVT+++G+T++ +     
Sbjct: 254 MEQVRDEGVDEDSVHAALLVVNLDSALDL-PRDKKSLLEPSPYVTLRLGQTEQESGIRNA 78

Query: 644 NLNPVWEEKFHFECHNSS 661
              P WEE F F   N +
Sbjct: 77  TTEPRWEENFRFFVANPN 24
>30040
          Length = 652

 Score = 36.6 bits (83), Expect = 0.080,   Method: Composition-based stats.
 Identities = 20/60 (33%), Positives = 33/60 (55%), Gaps = 5/60 (8%)
 Frame = -3

Query: 601 SAKITITVVCAQGLQAKDKTGSSDPYVTVQV---GKTKKRTKTIF--GNLNPVWEEKFHF 655
           + ++T+ ++ A+ L+      S+DP+V V +   GK  KR KT     ++NPVW E   F
Sbjct: 620 AERLTVVLMKAKDLKMSTSHPSADPFVRVSLLVEGKKVKRKKTSVRRASINPVWNEALAF 441
>07591
          Length = 796

 Score = 33.5 bits (75), Expect = 0.69,   Method: Compositional matrix adjust.
 Identities = 26/74 (35%), Positives = 32/74 (43%), Gaps = 10/74 (13%)
 Frame = +2

Query: 611 AQGLQAKDKTGSSDPYVTVQVGKTK------KRTKTIFGNLNPVW---EEKFHFEC-HNS 660
           A+ L  KD  G SDPY+ V    +        RT+ +  NLNP W   E      C  N 
Sbjct: 479 AKKLDKKDFLGKSDPYLEVLRATSDGSWQMVHRTEVVKNNLNPSWRPFELSMQTLCGGNH 658

Query: 661 SDRIKVRVWDEDDD 674
              IK  V+D D D
Sbjct: 659 QQNIKFDVYDWDSD 700
>20879
          Length = 1019

 Score = 31.2 bits (69), Expect = 3.9,   Method: Composition-based stats.
 Identities = 20/65 (30%), Positives = 31/65 (47%), Gaps = 5/65 (7%)
 Frame = -2

Query: 491 TYCYECEGL--LWGLARQG---MRCSECGVKCHEKCQDLLNADCLQRAAEKSSKHGAEDR 545
           T+C++   L  LW   R G   M+C +C   CH +C++ L   C+  A    S  G    
Sbjct: 781 THCHQTLHLCALWEEHRFGKVAMKCKDCRASCHPECKEKLPLPCIPSA---PSTPGTAKL 611

Query: 546 TQNII 550
           T+ I+
Sbjct: 610 TEGIL 596
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|23956396|ref|NP_705820.1| ER lipid raft associated 2
[Mus musculus]
         (340 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

32005                                                                 172   9e-57
11691                                                                  28   4.6  
14362                                                                  27   9.9  
>32005
          Length = 1092

 Score =  172 bits (435), Expect(2) = 9e-57,   Method: Compositional matrix adjust.
 Identities = 79/102 (77%), Positives = 91/102 (89%)
 Frame = +3

Query: 80  GGVMIYFDRIEVVNFLVPNAVYDIVKNYTADYDKALIFNKIHHELNQFCSVHTLQEVYIE 139
           GGV+IYF+RIEVVN L  +AV+DIVKNYTADYD+ LI+NKIHHELNQFCS+H LQEVYI+
Sbjct: 96  GGVIIYFERIEVVNKLDTSAVFDIVKNYTADYDRTLIYNKIHHELNQFCSIHNLQEVYID 275

Query: 140 LFDQIDENLKLALQQDLTSMAPGLVIQAVRVTKPNIPEAIRR 181
           LFDQIDENL+ ALQQDL  +APGL +QAVRVTKP IPE IR+
Sbjct: 276 LFDQIDENLRQALQQDLYQLAPGLTVQAVRVTKPKIPEQIRK 401

 Score = 66.2 bits (160), Expect(2) = 9e-57,   Method: Compositional matrix adjust.
 Identities = 28/33 (84%), Positives = 31/33 (93%)
 Frame = +2

Query: 49 FHLMLPFITSYKSVQTTLQTDEVKNVPCGTSGG 81
          +H MLP +TSY+SVQTTLQTDEVKNVPCGTSGG
Sbjct: 2  YHFMLPVLTSYRSVQTTLQTDEVKNVPCGTSGG 100

 Score = 91.7 bits (226), Expect(2) = 2e-33,   Method: Compositional matrix adjust.
 Identities = 53/87 (60%), Positives = 61/87 (70%), Gaps = 2/87 (2%)
 Frame = +1

Query: 173 PNIPEAIRR--NYELMESEKTKLLIAAQKQKVVEKEAETERKKALIEAEKVAQVAEITYG 230
           PN P ++ R  NYE ME EKTKLLI+ QKQKVVEKEAETERKKA+IEAEK AQVA+IT+ 
Sbjct: 370 PN-PRSLNRSANYEAMEGEKTKLLISIQKQKVVEKEAETERKKAVIEAEKQAQVAKITWQ 546

Query: 231 QKVMXXXXXXXXXXXXDAAFLAREKAK 257
           QK+M            D   LAREK +
Sbjct: 547 QKIMEKESEQKIAEIEDLTHLAREKPR 627

 Score = 68.6 bits (166), Expect(2) = 2e-33,   Method: Compositional matrix adjust.
 Identities = 30/55 (54%), Positives = 45/55 (81%)
 Frame = +3

Query: 253 REKAKADAECYTALKIAEANKLKLTPEYLQLMKYKAIASNSKIYFGKDIPNMFMD 307
           + KAKADA+ Y  +K AEANK+KLT E+++  KY+A+A+N+KI+FG  IP++F+D
Sbjct: 612 QRKAKADADYYRIIKDAEANKMKLTKEFVEFSKYQALAANTKIFFGNQIPDIFID 776
>11691
          Length = 472

 Score = 28.5 bits (62), Expect = 4.6,   Method: Compositional matrix adjust.
 Identities = 11/28 (39%), Positives = 19/28 (67%)
 Frame = -3

Query: 61  SVQTTLQTDEVKNVPCGTSGGVMIYFDR 88
           S+   L+T +V ++  G SGG++IY +R
Sbjct: 401 SIYFDLRTQKVSDIYSGGSGGILIYLNR 318
>14362
          Length = 535

 Score = 27.3 bits (59), Expect = 9.9,   Method: Compositional matrix adjust.
 Identities = 16/35 (45%), Positives = 20/35 (57%)
 Frame = +3

Query: 95  LVPNAVYDIVKNYTADYDKALIFNKIHHELNQFCS 129
           L    V+D V+NY A    ALI N I+  L+QF S
Sbjct: 300 LCSKTVWDCVQNYPAKPRDALI-NNIY*SLSQFLS 401
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31541796|ref|NP_081041.2| uridine-cytidine kinase
1-like 1 [Mus musculus]
         (548 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

11937                                                                 217   9e-57
11475                                                                 163   2e-40
27518                                                                 107   1e-23
>11937
          Length = 520

 Score =  217 bits (553), Expect = 9e-57,   Method: Compositional matrix adjust.
 Identities = 106/172 (61%), Positives = 131/172 (76%), Gaps = 1/172 (0%)
 Frame = +3

Query: 249 IEGVIKQYNKFVKPAFDQYIQPTMRLADIVVPRGSGNTVAIDLIVQHVHSQLEERELSVR 308
           +EGV+KQYNKFVKP+F+ YI+PTM  ADI+VPRG  N VAI+LIV HVH+QL  R   +R
Sbjct: 3   LEGVLKQYNKFVKPSFEHYIEPTMTYADIIVPRGGENDVAINLIVLHVHTQLLARGFKLR 182

Query: 309 AALAS-AHQCHPLPQTLSVLKSTPQVRGMHTIIRDKETSRDEFIFYSKRLMRLLIEHALS 367
             LA+  H+  P+P ++ VL+ TPQV G+HT IR++ET+RDEFIFYSKRLMRLL E A+S
Sbjct: 183 NKLANFEHKDEPMPDSVHVLEKTPQVHGIHTFIRNQETNRDEFIFYSKRLMRLLFECAMS 362

Query: 368 FLPFQDCTVQTPQGQDYVGKCYAGKQITGVSILRAGETMEPALRAVCKDVRI 419
            LPF+    +TPQG +Y GK  +  +I GVSILRAGETME ALR V KDV I
Sbjct: 363 MLPFKPVAAETPQGYEYSGKRLSDIKIAGVSILRAGETMEQALREVSKDVSI 518
>11475
          Length = 548

 Score =  163 bits (413), Expect = 2e-40,   Method: Compositional matrix adjust.
 Identities = 74/177 (41%), Positives = 112/177 (63%), Gaps = 7/177 (3%)
 Frame = -3

Query: 129 LLSMDSFYKVLTQQQQEQAACNNFNFDHPDAFDFDLIISTLKKLKQGRSVQVPIYDFTTH 188
           ++S DSFY+ L+ ++ ++A    FNFDHPDAFD DL+I TL+ +  G++VQ+P YD+ +H
Sbjct: 543 IISQDSFYRNLSPEEHQRAVAGKFNFDHPDAFDMDLMIQTLRDIAAGKTVQIPTYDYVSH 364

Query: 189 S-------RKKDWKTLYGANVIIFEGIMAFADKTLLELLDMKIFVDTDXXXXXXXXXXXX 241
                   R+   + +Y A+V++ EGI+ F    L ++  MK+FVDTD            
Sbjct: 363 KRLVSVQCRENTGQVVYPADVVLLEGILVFYFPELRDMFHMKLFVDTDPDTRLSRRVLRD 184

Query: 242 XXXXGRDIEGVIKQYNKFVKPAFDQYIQPTMRLADIVVPRGSGNTVAIDLIVQHVHS 298
               GRD+E ++ QY   VKPAF+++  PT + AD+++PRG+ NTVAIDLIVQH+  
Sbjct: 183 IKERGRDLEKILHQYTSLVKPAFEEFCLPTKKYADVIIPRGADNTVAIDLIVQHIQE 13
>27518
          Length = 444

 Score =  107 bits (267), Expect = 1e-23,   Method: Composition-based stats.
 Identities = 53/135 (39%), Positives = 83/135 (61%), Gaps = 1/135 (0%)
 Frame = +3

Query: 134 SFYKVLTQQQQEQAACNNFNFDHPDAFDFDLIISTLKKLKQGRSVQVPIYDFTTHSRK-K 192
           SFY+ LT  ++++A    FNFDHPDAF+ +L+  TL+ + +G  V++  YD+ T+S   +
Sbjct: 3   SFYRELTLAEKQKAQKGKFNFDHPDAFNEELMFDTLQLILKGHKVKIASYDYRTNSLDYE 182

Query: 193 DWKTLYGANVIIFEGIMAFADKTLLELLDMKIFVDTDXXXXXXXXXXXXXXXXGRDIEGV 252
           +   +Y A+V++FEGI+ F    + EL  MK+FVDTD                GRD++ V
Sbjct: 183 NTLVIYPADVVLFEGILVFYFPKIRELFHMKLFVDTDSDTRLARRVPRDINERGRDLDAV 362

Query: 253 IKQYNKFVKPAFDQY 267
           + QY  FVKPAF+++
Sbjct: 363 LTQYMTFVKPAFEEF 407
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6681195|ref|NP_031890.1| post-synaptic density
protein 95 isoform 1 [Mus musculus]
         (724 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

08480                                                                 218   9e-57
29974                                                                 174   2e-43
13641                                                                 131   8e-31
29705                                                                 114   2e-25
27435                                                                  91   2e-18
35802                                                                  87   3e-17
33804                                                                  71   3e-16
11512                                                                  78   1e-14
20073                                                                  69   9e-12
29636                                                                  54   2e-07
27345                                                                  47   4e-05
03831                                                                  47   4e-05
03499                                                                  46   5e-05
39267                                                                  41   0.002
26154                                                                  38   0.014
38751                                                                  38   0.017
01502                                                                  36   0.057
02951                                                                  36   0.060
30740                                                                  34   0.27 
37412                                                                  33   0.57 
37239                                                                  31   2.0  
28981                                                                  30   2.6  
33158                                                                  30   3.1  
29193                                                                  29   8.2  
>08480
          Length = 698

 Score =  218 bits (554), Expect = 9e-57,   Method: Compositional matrix adjust.
 Identities = 118/236 (50%), Positives = 149/236 (63%), Gaps = 47/236 (19%)
 Frame = -1

Query: 345 GPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKI 404
           GPADLSG+LR+GD+ILSVN VD+  A+HEQAA ALK AG TV IIAQYKPE+Y+RFEAKI
Sbjct: 698 GPADLSGDLRRGDKILSVNDVDVERATHEQAAQALKRAGDTVEIIAQYKPEDYNRFEAKI 519

Query: 405 HDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFHFGDVLHVID 464
            DLREQ+MN+S G    SLR+  KR  ++RALFDY+ +KD G  S+ L FH+GD+LHV +
Sbjct: 518 QDLREQMMNNSAG----SLRTTQKRTMFVRALFDYEPSKDSGLPSRGLWFHYGDILHVTN 351

Query: 465 ASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGS----------- 513
           ASD+EWWQA+R+  D + + +G IPSKRRVER+E +RL+   +G +S S           
Sbjct: 350 ASDDEWWQAKRILPDGKEEGMGIIPSKRRVERKERARLRNVKFGKNSTSTDKPVKDKGKK 171

Query: 514 -QGR-----------------------------------EDSVLSYETVTQMEVHY 533
             GR                                   E+ VLSYETVTQ E+ Y
Sbjct: 170 KSGRMFPFKKGKDQSGSEDVSGDEVEEGNLPSDSDSNRGEEPVLSYETVTQQELKY 3

 Score = 43.1 bits (100), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 26/61 (42%), Positives = 32/61 (52%)
 Frame = -1

Query: 103 GAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKIIEIK 162
           G A   G LR  D IL VN+VDV   TH  A +ALK AG  V + + + KP      E K
Sbjct: 698 GPADLSGDLRRGDKILSVNDVDVERATHEQAAQALKRAGDTVEI-IAQYKPEDYNRFEAK 522

Query: 163 L 163
           +
Sbjct: 521 I 519

 Score = 39.3 bits (90), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 21/44 (47%), Positives = 25/44 (56%)
 Frame = -1

Query: 198 GAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYL 241
           G A   G L+ GDKIL+VN V +E   HE A  ALK   D V +
Sbjct: 698 GPADLSGDLRRGDKILSVNDVDVERATHEQAAQALKRAGDTVEI 567
>29974
          Length = 344

 Score =  174 bits (440), Expect = 2e-43,   Method: Compositional matrix adjust.
 Identities = 80/108 (74%), Positives = 93/108 (86%)
 Frame = +1

Query: 548 NDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSH 607
           NDDL+SEFPDKFGSC+PHTTR +R  E  G+DYHFVSSRE+ME+DIQ H FIEAG YN +
Sbjct: 1   NDDLISEFPDKFGSCIPHTTRERRTNEEPGQDYHFVSSREQMERDIQNHLFIEAGVYNDN 180

Query: 608 LYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSL 655
           LYGTSV SV+EVAEQG+HCILDVS NA++RLQ A L+PIAIFI+P  L
Sbjct: 181 LYGTSVASVKEVAEQGRHCILDVSGNAIKRLQVAGLYPIAIFIKPSRL 324
>13641
          Length = 2081

 Score =  131 bits (330), Expect = 8e-31,   Method: Compositional matrix adjust.
 Identities = 102/342 (29%), Positives = 163/342 (47%), Gaps = 59/342 (17%)
 Frame = +2

Query: 415 SLGSGTASLRSNP--------KRGFYIRALFDYDKTKDCGFLSQ--ALSFHFGDVLHVID 464
           S  SG+ +L+  P        KR   ++A+F ++   D     +   LSF  GD+LH+++
Sbjct: 80  SKTSGSLTLKLVPSRRTPGSKKREMVVKAMFSFNSKLDDNIPCKEAGLSFQQGDILHIVN 259

Query: 465 ASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRL-KAKD------------WGSSS 511
             D  WWQA + H D++    G IPS+   ER+E  R  K+K+            +    
Sbjct: 260 QEDAIWWQAYK-HGDAK-KRAGLIPSRHYHERQEVLRKSKSKEGRHMARSISPCRYSPKV 433

Query: 512 GSQGR------------------EDSVLSYETVTQM--EVHYARPIIILGPT---KDRAN 548
             Q R                   D + +Y+ V     +  + RPI+++G     ++   
Sbjct: 434 PKQRRLRKTMYHIVQNGALTDFDTDEIPAYDEVEHFTPKPRHFRPIVLIGAPGIGRNELK 613

Query: 549 DDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHL 608
             L +  P  F   VP+TTR K+ +E DG++YHFVS RE ME+ I A KF+E G+++ HL
Sbjct: 614 RRLKASNPMHFLEVVPYTTRTKKPFEEDGKEYHFVS-REDMEESIIAQKFVEYGEHHGHL 790

Query: 609 YGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLE----INKR 664
           YGTSV+S+++V   GK C+L     A++ L+   L P  IFI+  +LE + E       R
Sbjct: 791 YGTSVESIKQVIAAGKVCLLTPHTQALKFLRTYELKPYVIFIKSPTLEKLKESRMPARAR 970

Query: 665 ITEEQARKAF---------DRATKLEQEFTECFSAIVEGDSF 697
            TE  + + F         + + +LE+ +   F   +  DS 
Sbjct: 971 ATEADSIRPFSIEELEEMAETSRRLEERYGHVFDITIVNDSL 1096
>29705
          Length = 674

 Score =  114 bits (284), Expect = 2e-25,   Method: Compositional matrix adjust.
 Identities = 73/174 (41%), Positives = 96/174 (55%), Gaps = 5/174 (2%)
 Frame = -1

Query: 85  NPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIV 144
           NPHIGDDPSI+ITK+IP G   +                  R V H +     +     +
Sbjct: 674 NPHIGDDPSIYITKLIPRGCCCRGWPSETERH--HCQSGH*RRVQHHS--HRRR*CPQTL 507

Query: 145 RLYVMRRKPPAEKIIEIKLIKGP-----KGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGA 199
           R   +     AE          P     +G G     G GNQHIPGDN I++TK+IEGG+
Sbjct: 506 RQQSLLASETAEDSDRKSHRHRPGQGS*QGSGIQHCRGKGNQHIPGDNGIFITKVIEGGS 327

Query: 200 AHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSD 253
           A +DGR+ + D++LAVN   LEDV HE+AVAALK+T DVV L +AKP+  Y++D
Sbjct: 326 AEQDGRIAVMDRLLAVNEHNLEDVTHEEAVAALKSTGDVVRLTIAKPT--YIAD 171

 Score = 73.6 bits (179), Expect(2) = 3e-14,   Method: Compositional matrix adjust.
 Identities = 38/77 (49%), Positives = 48/77 (62%)
 Frame = -1

Query: 74  GLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAA 133
           G G     G  N HI  D  IFITK+I GG+A QDGR+ V D +L VNE ++ +VTH  A
Sbjct: 419 GSGIQHCRGKGNQHIPGDNGIFITKVIEGGSAEQDGRIAVMDRLLAVNEHNLEDVTHEEA 240

Query: 134 VEALKEAGSIVRLYVMR 150
           V ALK  G +VRL + +
Sbjct: 239 VAALKSTGDVVRLTIAK 189

 Score = 23.5 bits (49), Expect(2) = 3e-14,   Method: Compositional matrix adjust.
 Identities = 12/18 (66%), Positives = 14/18 (77%), Gaps = 1/18 (5%)
 Frame = -2

Query: 65  EITLERG-NSGLGFSIAG 81
           +I L +G N GLGFSIAG
Sbjct: 448 DIDLVKGVNKGLGFSIAG 395

 Score = 44.7 bits (104), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 24/67 (35%), Positives = 41/67 (61%)
 Frame = -1

Query: 322 GLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKN 381
           G G   + G++G  IFI+ ++ GG A+  G +   D++L+VN  +L + +HE+A  ALK+
Sbjct: 395 GKGNQHIPGDNG--IFITKVIEGGSAEQDGRIAVMDRLLAVNEHNLEDVTHEEAVAALKS 222

Query: 382 AGQTVTI 388
            G  V +
Sbjct: 221 TGDVVRL 201
>27435
          Length = 456

 Score = 90.9 bits (224), Expect = 2e-18,   Method: Compositional matrix adjust.
 Identities = 45/151 (29%), Positives = 87/151 (57%), Gaps = 5/151 (3%)
 Frame = +1

Query: 574 EIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSAN 633
           E +G+DYHF++ R   E D+ + KF+E G++  +LYGT+V++VR+V +QG+ CIL++   
Sbjct: 1   EHNGKDYHFIT-RAVFEADMLSGKFVEYGEFQGNLYGTTVEAVRQVIQQGRICILNLGPE 177

Query: 634 AVRRLQAAHLHPIAIFIRPRSLENVLEINK-----RITEEQARKAFDRATKLEQEFTECF 688
           +++ L+   L P  IFI P  +E + ++       R T++Q ++  +R  ++E+ ++  F
Sbjct: 178 SLKNLRETELKPYIIFISPPXMEKLRQLQMALGKPRPTDDQVKEVIERGREMEEMYSHYF 357

Query: 689 SAIVEGDSFEEIYHKVKRVIEDLSGPYIWVP 719
             I+        + ++ + I  +     WVP
Sbjct: 358 DYILVNMELNRAFDELLQEINRIETEPQWVP 450
>35802
          Length = 571

 Score = 86.7 bits (213), Expect = 3e-17,   Method: Composition-based stats.
 Identities = 49/155 (31%), Positives = 90/155 (58%), Gaps = 10/155 (6%)
 Frame = +1

Query: 574 EIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSAN 633
           E+ GRDYHF +SR   E D+ + KF+E G++ S+LYGTSV++VR+V  QG+ C+L++   
Sbjct: 1   EMTGRDYHF-TSRSMFEADMLSGKFLEYGEFQSNLYGTSVEAVRQVILQGRVCLLNLEPE 177

Query: 634 AVRRLQAAHLHPIAIFIRPRSLENVLEIN-----KRITEEQARKAFDRATKLEQEFTECF 688
           +++ L+   L P   F+ P ++E + +++      R T++Q +   D+  ++E  +   F
Sbjct: 178 SLKILRETDLKPYTXFVCPPNMEKLRQLHIAMGKIRPTDDQLKTVMDKGREMEDMYGHFF 357

Query: 689 S-AIVEGD---SFEEIYHKVKRV-IEDLSGPYIWV 718
              +V  D   S +E+  ++ R+ +E    P  W+
Sbjct: 358 DYKLVNMDVDRSVQELMAEINRIEVEPQWVPVTWM 462
>33804
          Length = 621

 Score = 71.2 bits (173), Expect(2) = 3e-16,   Method: Compositional matrix adjust.
 Identities = 32/54 (59%), Positives = 41/54 (75%)
 Frame = -1

Query: 671 RKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL 724
           RK F+RA K+EQEF E F+ +V+GD+ EEIY KVK +I   SGP IWVP++E L
Sbjct: 564 RKHFERAIKMEQEFGEYFTGVVQGDTIEEIYSKVKSMIWSQSGPNIWVPSKESL 403

 Score = 32.7 bits (73), Expect(2) = 3e-16,   Method: Composition-based stats.
 Identities = 12/22 (54%), Positives = 21/22 (95%)
 Frame = -3

Query: 653 RSLENVLEINKRITEEQARKAF 674
           +S+++V+E+N+R+TEEQA+K F
Sbjct: 619 KSVDSVMEMNRRMTEEQAKKTF 554
>11512
          Length = 1006

 Score = 78.2 bits (191), Expect = 1e-14,   Method: Compositional matrix adjust.
 Identities = 55/161 (34%), Positives = 84/161 (52%), Gaps = 22/161 (13%)
 Frame = -3

Query: 580  YHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQ 639
            Y FV+ REKM+ DI+A KF+E G+Y  HLYGTS +SV+ +   G  C+L     A++ L+
Sbjct: 1004 YIFVA-REKMDADIEAGKFVEHGEYKGHLYGTSAESVKSIVNAGCVCVLSPHYQAIKTLR 828

Query: 640  AAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATK---LEQEFTECFSA------ 690
               L P  I I+P  L ++L+  +  TE +A+  FD A      ++EF +   +      
Sbjct: 827  TXQLKPFLIHIKPPEL-DILKSTR--TEARAKSTFDEANARSFTDEEFEDMIKSTXRIDF 657

Query: 691  ---------IVEGD---SFEEIYHKVKRV-IEDLSGPYIWV 718
                     IV G+   +FE +   V+R+  E L  P +WV
Sbjct: 656  TYGHFFDVEIVNGELLAAFEXLVQHVQRLENEPLWAPSMWV 534
>20073
          Length = 582

 Score = 68.6 bits (166), Expect = 9e-12,   Method: Composition-based stats.
 Identities = 37/83 (44%), Positives = 52/83 (62%), Gaps = 1/83 (1%)
 Frame = +3

Query: 322 GLGFNIVGG-EDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALK 380
           GLGFN++GG E    I+IS I+ GG AD    L++GDQ+LSVNGV +    HE+A   LK
Sbjct: 3   GLGFNVMGGKEQSSPIYISRIIPGGVADRLNCLKRGDQLLSVNGVSVEGEYHEKAVELLK 182

Query: 381 NAGQTVTIIAQYKPEEYSRFEAK 403
            A  +V ++ +Y P+     EA+
Sbjct: 183 LAQGSVRLVVRYTPQILEEMEAR 251

 Score = 51.6 bits (122), Expect = 1e-06,   Method: Composition-based stats.
 Identities = 34/80 (42%), Positives = 44/80 (55%)
 Frame = +3

Query: 74  GLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAA 133
           GLGF++ GG +         I+I++IIPGG A +   L+  D +L VN V V    H  A
Sbjct: 3   GLGFNVMGGKEQ-----SSPIYISRIIPGGVADRLNCLKRGDQLLSVNGVSVEGEYHEKA 167

Query: 134 VEALKEAGSIVRLYVMRRKP 153
           VE LK A   VRL V+R  P
Sbjct: 168 VELLKLAQGSVRL-VVRYTP 224

 Score = 49.3 bits (116), Expect = 5e-06,   Method: Composition-based stats.
 Identities = 29/65 (44%), Positives = 40/65 (61%)
 Frame = +3

Query: 169 GLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDA 228
           GLGF++ GG   Q  P    IY+++II GG A +   L+ GD++L+VN V +E   HE A
Sbjct: 3   GLGFNVMGG-KEQSSP----IYISRIIPGGVADRLNCLKRGDQLLSVNGVSVEGEYHEKA 167

Query: 229 VAALK 233
           V  LK
Sbjct: 168 VELLK 182
>29636
          Length = 354

 Score = 53.9 bits (128), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 36/96 (37%), Positives = 47/96 (48%), Gaps = 4/96 (4%)
 Frame = +1

Query: 425 SNPKRGFYIRALFDYDKTKD----CGFLSQALSFHFGDVLHVIDASDEEWWQARRVHSDS 480
           + P    ++RALF+YD   D    C  L   +SF  GD+LH I  SD  WWQA R   D+
Sbjct: 52  AKPGDIMHLRALFNYDPEDDPYIPCREL--GISFLKGDILHAIQLSDSNWWQAHREGEDA 225

Query: 481 ETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGR 516
                G IPSK   E+RE  R +       +  +GR
Sbjct: 226 HM-LAGLIPSKAFQEQRESVRQQLNAENKENKKRGR 330
>27345
          Length = 496

 Score = 46.6 bits (109), Expect = 4e-05,   Method: Composition-based stats.
 Identities = 22/62 (35%), Positives = 35/62 (56%)
 Frame = +3

Query: 184 PGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKV 243
           PG   I++  + +GGAA KDGR+Q+ D+I+ V+   L  V    A + L+NT   V   +
Sbjct: 12  PGKLGIFIKTLTDGGAAQKDGRIQVNDQIIEVDGKSLVGVTQAYAASVLRNTSGQVTFHI 191

Query: 244 AK 245
            +
Sbjct: 192 GR 197

 Score = 45.4 bits (106), Expect = 7e-05,   Method: Composition-based stats.
 Identities = 24/63 (38%), Positives = 36/63 (57%)
 Frame = +3

Query: 94  IFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKP 153
           IFI  +  GGAA +DGR++VND I+ V+   +  VT + A   L+     V  ++ R K 
Sbjct: 27  IFIKTLTDGGAAQKDGRIQVNDQIIEVDGKSLVGVTQAYAASVLRNTSGQVTFHIGRDKD 206

Query: 154 PAE 156
           PA+
Sbjct: 207 PAK 215

 Score = 36.6 bits (83), Expect = 0.038,   Method: Composition-based stats.
 Identities = 20/53 (37%), Positives = 27/53 (50%)
 Frame = +3

Query: 335 GIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVT 387
           GIFI  +  GG A   G ++  DQI+ V+G  L   +   AA  L+N    VT
Sbjct: 24  GIFIKTLTDGGAAQKDGRIQVNDQIIEVDGKSLVGVTQAYAASVLRNTSGQVT 182
>03831
          Length = 1143

 Score = 46.6 bits (109), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 30/97 (30%), Positives = 53/97 (54%), Gaps = 3/97 (3%)
 Frame = +3

Query: 311 PRRIVIHRGS--TGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLR 368
           PR   I R S   G GFN+   +   G FI  +  G PA+ +G L+ GD+I+ VNG ++ 
Sbjct: 129 PRLCHIVRWSDFNGYGFNLHAEKGKAGQFIGKVDEGSPAEAAG-LKAGDRIVEVNGTNIG 305

Query: 369 NASHEQAAIALKNAG-QTVTIIAQYKPEEYSRFEAKI 404
           N +H+Q    +K  G +T  ++   + +++ + E ++
Sbjct: 306 NENHQQVVGRIKAGGDETRLLVVDQETDQHYKEEKRV 416

 Score = 45.1 bits (105), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 49/210 (23%), Positives = 86/210 (40%), Gaps = 10/210 (4%)
 Frame = +3

Query: 190 YVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVA----- 244
           ++ K+ EG  A   G L+ GD+I+ VN   + +  H+  V  +K   D   L V      
Sbjct: 213 FIGKVDEGSPAEAAG-LKAGDRIVEVNGTNIGNENHQQVVGRIKAGGDETRLLVVDQETD 389

Query: 245 ---KPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDL 301
              K     +          T+  +  DN  +  + +      A   T P   S      
Sbjct: 390 QHYKEEKRVVRGDLPETRFMTAAREQKDNXENQEAEIAA-VVEATNGTEPEPQS------ 548

Query: 302 LGEEDIPREPRRIVIHRGST--GLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQI 359
           L +E     PR   + + +   G GFN+   +D  G +I  +    PA+  G L++GD+I
Sbjct: 549 LPDESSLYAPRLCHLCKWADFDGYGFNLHAEKDKPGQYIGSVDPNSPAETGG-LKEGDRI 725

Query: 360 LSVNGVDLRNASHEQAAIALKNAGQTVTII 389
           + VNG ++   +H      +K+ G   +++
Sbjct: 726 IEVNGENIETTNHTAVIQNIKSRGDKTSML 815
>03499
          Length = 1247

 Score = 46.2 bits (108), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 31/98 (31%), Positives = 48/98 (48%), Gaps = 2/98 (2%)
 Frame = -3

Query: 58  EGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSI 117
           E + E+ + +L +   G GF+I G +D+P   D   + I  ++P G A  +G+L+  D I
Sbjct: 996 ELQGEFVKTSLVKSVRGFGFTIVG-SDHP---DTEFLQIKNVVPNGPAYLNGKLKTGDVI 829

Query: 118 LFVNEVDVREVTHSAAVEALK--EAGSIVRLYVMRRKP 153
           +FVN   V   TH   V   +    G  V L + R  P
Sbjct: 828 VFVNTTCVLGYTHQDVVSLFQTISPGETVTLEICRGYP 715

 Score = 36.2 bits (82), Expect = 0.054,   Method: Compositional matrix adjust.
 Identities = 25/79 (31%), Positives = 40/79 (50%)
 Frame = -3

Query: 62  EYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVN 121
           E   I + RG  G GF+IA   D+P+        + +I+  G       L+ ND +  +N
Sbjct: 435 EILSINIVRGQMGFGFTIA---DSPY-----GQKVKQILDKGRCKT---LQENDLLQEIN 289

Query: 122 EVDVREVTHSAAVEALKEA 140
            VDV+ +TH+  V+ LK+ 
Sbjct: 288 RVDVKRMTHAQIVQVLKDC 232
>39267
          Length = 456

 Score = 40.8 bits (94), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 20/64 (31%), Positives = 41/64 (64%)
 Frame = +1

Query: 169 GLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDA 228
           GLGF+I+G +        + IYV+++   G A + G++ +GD+I +V ++  +++++EDA
Sbjct: 115 GLGFNISGNM-------RDGIYVSQLHNRGPASESGKIHVGDRIQSV-TIAYDNIVYEDA 270

Query: 229 VAAL 232
           +  L
Sbjct: 271 LTIL 282

 Score = 37.7 bits (86), Expect = 0.017,   Method: Compositional matrix adjust.
 Identities = 25/61 (40%), Positives = 34/61 (55%)
 Frame = +1

Query: 322 GLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKN 381
           GLGFNI G    +GI++S +   GPA  SG++  GD+I SV  +   N  +E A   L  
Sbjct: 115 GLGFNISGNMR-DGIYVSQLHNRGPASESGKIHVGDRIQSVT-IAYDNIVYEDALTILSY 288

Query: 382 A 382
           A
Sbjct: 289 A 291
>26154
          Length = 446

 Score = 38.1 bits (87), Expect = 0.014,   Method: Composition-based stats.
 Identities = 19/48 (39%), Positives = 31/48 (64%)
 Frame = -3

Query: 198 GAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAK 245
           G+AH+ G +Q GDK++A+N V L+    +DA   L+   ++V LKV +
Sbjct: 408 GSAHRCGSIQAGDKLMAINDVRLDTCTVDDATHLLELPDELVKLKVQR 265

 Score = 32.7 bits (73), Expect = 0.58,   Method: Composition-based stats.
 Identities = 19/51 (37%), Positives = 29/51 (56%), Gaps = 1/51 (1%)
 Frame = -3

Query: 314 IVIHRGSTGLGFNIVGGEDG-EGIFISFILAGGPADLSGELRKGDQILSVN 363
           + ++R    LG  I G ED  + I IS + AGG A  +G +  GD++L +N
Sbjct: 222 VQLYRHGGPLGITISGTEDPLDNIVISELTAGGLAQKTGAMHVGDRLLGIN 70
>38751
          Length = 329

 Score = 37.7 bits (86), Expect = 0.017,   Method: Composition-based stats.
 Identities = 26/70 (37%), Positives = 35/70 (50%)
 Frame = +3

Query: 329 GGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTI 388
           G E G  I +  I  G  A+  G L  GD+IL VNG D  + +H +A   ++NA   V +
Sbjct: 18  GKEYGTPIVVYVIEEGCQAEQQG-LNIGDRILDVNGTDFTHLTHAEAVTIMRNA-WNVIM 191

Query: 389 IAQYKPEEYS 398
             Q  PE  S
Sbjct: 192 TVQPCPESDS 221
>01502
          Length = 1949

 Score = 35.8 bits (81), Expect = 0.057,   Method: Compositional matrix adjust.
 Identities = 17/43 (39%), Positives = 26/43 (60%)
 Frame = +1

Query: 334 EGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAA 376
           +GI+++FI    PA   G L+  D+IL +NG D    +H+QA 
Sbjct: 31  KGIYVTFIYENSPAARCG-LQLHDKILQLNGKDFTVVTHKQAV 156

 Score = 35.0 bits (79), Expect = 0.11,   Method: Compositional matrix adjust.
 Identities = 22/64 (34%), Positives = 37/64 (57%)
 Frame = +1

Query: 91  DPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMR 150
           D  I++T I     AA+ G L+++D IL +N  D   VTH  AVE +++   ++++ V R
Sbjct: 28  DKGIYVTFIYENSPAARCG-LQLHDKILQLNGKDFTVVTHKQAVENIRKK-PVLKMLVYR 201

Query: 151 RKPP 154
           +  P
Sbjct: 202 KGVP 213
>02951
          Length = 1076

 Score = 35.8 bits (81), Expect = 0.060,   Method: Compositional matrix adjust.
 Identities = 18/47 (38%), Positives = 27/47 (57%)
 Frame = +2

Query: 330 GEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAA 376
           G   +GI+++FI    PA   G L+  D+IL +NG D    +H+QA 
Sbjct: 5   GYPDKGIYVTFIYENSPAARCG-LQLHDKILQLNGKDFTVVTHKQAV 142

 Score = 35.8 bits (81), Expect = 0.071,   Method: Compositional matrix adjust.
 Identities = 22/64 (34%), Positives = 37/64 (57%)
 Frame = +2

Query: 91  DPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMR 150
           D  I++T I     AA+ G L+++D IL +N  D   VTH  AVE +++   ++++ V R
Sbjct: 14  DKGIYVTFIYENSPAARCG-LQLHDKILQLNGKDFTVVTHKQAVENIRKK-PVLKMLVYR 187

Query: 151 RKPP 154
           +  P
Sbjct: 188 KGVP 199
>30740
          Length = 488

 Score = 33.9 bits (76), Expect = 0.27,   Method: Compositional matrix adjust.
 Identities = 15/40 (37%), Positives = 20/40 (50%)
 Frame = +2

Query: 450 QALSFHFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIP 489
           + L F  GD+L +I   +EEWW AR  H     D +   P
Sbjct: 227 EDLPFSKGDILELISKDEEEWWTARDKHGRVGQDPLSSTP 346
>37412
          Length = 757

 Score = 32.7 bits (73), Expect = 0.57,   Method: Compositional matrix adjust.
 Identities = 17/57 (29%), Positives = 31/57 (54%)
 Frame = -3

Query: 623 GKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATK 679
           GK C+LDV+  +++ L+ A   P  +FI   S+E +     ++  E  R+ F R ++
Sbjct: 629 GKMCVLDVNPTSLKVLKTAEFLPYIVFIAAPSVEAL-----KVMYEDGRR-FARGSR 477
>37239
          Length = 453

 Score = 30.8 bits (68), Expect = 2.0,   Method: Compositional matrix adjust.
 Identities = 14/28 (50%), Positives = 20/28 (71%)
 Frame = -3

Query: 185 GDNSIYVTKIIEGGAAHKDGRLQIGDKI 212
           G + IY+  I  GGAA KDG+L +GD++
Sbjct: 85  GRHGIYIRHITIGGAAAKDGQLAVGDEL 2

 Score = 28.5 bits (62), Expect = 8.9,   Method: Compositional matrix adjust.
 Identities = 13/25 (52%), Positives = 17/25 (68%)
 Frame = -3

Query: 93  SIFITKIIPGGAAAQDGRLRVNDSI 117
            I+I  I  GGAAA+DG+L V D +
Sbjct: 76  GIYIRHITIGGAAAKDGQLAVGDEL 2
>28981
          Length = 896

 Score = 30.4 bits (67), Expect = 2.6,   Method: Compositional matrix adjust.
 Identities = 23/77 (29%), Positives = 35/77 (45%), Gaps = 3/77 (3%)
 Frame = -3

Query: 8   TTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIV---NTDTLEAPGYELQVNGTEGEMEYE 64
            T+++    EDT  +  SP    N A  PP ++     D L+   YE +    E  +E E
Sbjct: 825 CTEQFLCTSEDTKNVRVSPLLQTNFARLPPALILVPEVDPLKDACYEYKKKMKEAGIEAE 646

Query: 65  EITLERGNSGLGFSIAG 81
            +TL+    G  FS+ G
Sbjct: 645 SLTLKGAVHGF-FSLPG 598
>33158
          Length = 1075

 Score = 30.0 bits (66), Expect = 3.1,   Method: Compositional matrix adjust.
 Identities = 12/26 (46%), Positives = 19/26 (73%)
 Frame = +2

Query: 187  NSIYVTKIIEGGAAHKDGRLQIGDKI 212
            +S+ + +I++GGAA K G L  GD+I
Sbjct: 998  DSVLIARIVKGGAAEKSGLLHEGDEI 1075
>29193
          Length = 1321

 Score = 28.9 bits (63), Expect = 8.2,   Method: Compositional matrix adjust.
 Identities = 14/41 (34%), Positives = 18/41 (43%)
 Frame = +2

Query: 274  HSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRI 314
            H S L    PTA  PT     SP    +L +  +P  P R+
Sbjct: 1013 HCSLLNCVIPTATCPTVGFHXSPACPSILLDNPLPTTPIRL 1135
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6755076|ref|NP_035230.1| protein kinase, cAMP
dependent, catalytic, beta [Mus musculus]
         (351 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

03240                                                                 216   9e-57
30755                                                                 170   7e-43
18484                                                                 142   2e-34
27405                                                                 120   8e-28
00486                                                                 120   9e-28
31885                                                                 115   3e-26
15910                                                                 114   7e-26
12721                                                                 108   3e-24
18921                                                                 105   3e-23
09606                                                                 103   7e-23
26560                                                                 100   1e-21
01707                                                                  99   2e-21
14420                                                                  99   2e-21
00300                                                                  98   5e-21
18663                                                                  96   2e-20
26156                                                                  84   6e-20
13592                                                                  93   1e-19
01392                                                                  93   2e-19
06405                                                                  85   4e-17
01060                                                                  84   7e-17
17975                                                                  84   8e-17
13066                                                                  84   1e-16
21079                                                                  81   6e-16
17722                                                                  79   2e-15
21433                                                                  77   7e-15
01756                                                                  76   2e-14
00392                                                                  75   3e-14
01718                                                                  74   9e-14
09007                                                                  71   6e-13
27546                                                                  70   1e-12
19094                                                                  70   2e-12
25019                                                                  68   5e-12
19761                                                                  67   7e-12
26711                                                                  67   8e-12
11185                                                                  65   4e-11
13212                                                                  64   6e-11
28638                                                                  64   8e-11
29581                                                                  64   9e-11
14126                                                                  62   3e-10
01966                                                                  62   3e-10
38560                                                                  60   1e-09
28157                                                                  60   1e-09
21808                                                                  59   3e-09
19301                                                                  58   6e-09
04852                                                                  58   7e-09
04591                                                                  57   8e-09
11780                                                                  57   1e-08
32957                                                                  56   2e-08
12786                                                                  54   7e-08
03508                                                                  54   7e-08
07940                                                                  54   9e-08
04138                                                                  53   2e-07
16708                                                                  52   4e-07
20152                                                                  52   5e-07
37602                                                                  49   4e-06
00715                                                                  49   4e-06
14116                                                                  47   1e-05
27274                                                                  46   2e-05
07291                                                                  45   3e-05
33586                                                                  45   4e-05
02638                                                                  45   4e-05
17300                                                                  45   4e-05
17932                                                                  44   9e-05
18401                                                                  42   3e-04
14477                                                                  42   4e-04
12672                                                                  41   8e-04
20640                                                                  41   8e-04
31489                                                                  41   8e-04
29590                                                                  40   0.001
11404                                                                  40   0.002
26009                                                                  40   0.002
37063                                                                  39   0.002
18481                                                                  39   0.002
17516                                                                  38   0.005
17637                                                                  37   0.011
18996                                                                  37   0.011
17253                                                                  36   0.023
06358                                                                  35   0.031
25360                                                                  35   0.036
11089                                                                  35   0.041
21210                                                                  34   0.070
17591                                                                  33   0.20 
01106                                                                  33   0.23 
21800                                                                  33   0.23 
26052                                                                  32   0.50 
00638                                                                  31   0.92 
36481                                                                  31   0.97 
16350                                                                  30   1.6  
36002                                                                  30   2.1  
30339                                                                  29   2.3  
06167                                                                  29   2.9  
23319                                                                  28   4.4  
29360                                                                  28   5.1  
24241                                                                  28   7.1  
31120                                                                  28   8.2  
>03240
          Length = 1683

 Score =  216 bits (551), Expect = 9e-57,   Method: Compositional matrix adjust.
 Identities = 128/356 (35%), Positives = 190/356 (53%), Gaps = 56/356 (15%)
 Frame = -3

Query: 44   FERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVEFPF 103
            FE+ KTLG G+FG V L +   T   YAMK L K  V+K  Q+ H   E+ IL   +  +
Sbjct: 1285 FEKIKTLGVGAFGEVSLCRKNDTGMLYAMKTLRKSDVLKRNQVAHVKAERDILAEADNEW 1106

Query: 104  LVRLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDL 163
            +V+L YSF+D++ LY VM+YVPGG++   L R+    EP ARFY A++V   E +H +  
Sbjct: 1105 VVKLYYSFQDHNYLYFVMDYVPGGDLMGLLIRMEILDEPLARFYVAELVQAIESVHRMGF 926

Query: 164  IYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTWT------------------------- 198
            I+RD+KP+N+LID  G+I++TDFG      G  WT                         
Sbjct: 925  IHRDIKPDNILIDRNGHIKLTDFGLC---TGFRWTHNSKYYQRDGTHARQDSMEVKCQLD 755

Query: 199  -------------------------LCGTPEYLAPEIILSK--GYNKAVDWWALGVLIYE 231
                                     L GTP Y+APE +LS+  GY    DWW++GV+++E
Sbjct: 754  EQCQCEILKPLERRRKREQRCLAHSLVGTPNYIAPE-VLSRLGGYTSVCDWWSVGVILFE 578

Query: 232  MAAGYPPFFADQPIQIYEKIVSGK--VRFP--SHFSSDLKDLLRNLLQVDLTKRFGNLKN 287
            M  G+PPF+A+ P +   K+++ K  ++ P  S+ S   KDL+  L       R G   N
Sbjct: 577  MLVGHPPFYANTPAETQYKVINWKDMLKIPRESNLSQPAKDLILRLC-CGSDDRLG--LN 407

Query: 288  GVSDIKTHKWFATTDWIAIYQRKVEAPFIPKFRGSGDTSNFDDYEEEEIRVSITEK 343
            G  +IKTH +FA  ++  +  RK + P++P  R + DTSNFD  + +++R S +E+
Sbjct: 406  GAGEIKTHMFFAGVNFETL--RKQQPPYVPNIRYATDTSNFDPVDPDKLRNSDSEE 245
>30755
          Length = 1137

 Score =  170 bits (431), Expect = 7e-43,   Method: Compositional matrix adjust.
 Identities = 88/218 (40%), Positives = 125/218 (57%), Gaps = 4/218 (1%)
 Frame = +2

Query: 132 HLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKR 191
           HL     F+E   RFY A+I+    YLHS  +IYRDLK ENLL+D  G+I+V DFG  K 
Sbjct: 2   HLSHERIFTEERTRFYGAEIISALGYLHSQGIIYRDLKLENLLLDKDGHIKVADFGLCKE 181

Query: 192 --VKGRTW-TLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIY 248
               GRT  T CGTPEYLAPE++    Y +AVDWW  GV++YEM  G  PF+      ++
Sbjct: 182 DITYGRTTKTFCGTPEYLAPEVLDDNDYGRAVDWWGTGVVMYEMICGRLPFYNRDHDVLF 361

Query: 249 EKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDWIAIYQ 308
             I+   V+FP + + + K LL  LL  D   R G  ++ V +I+ H +FA+ +W  + Q
Sbjct: 362 TLILVEDVKFPRNITDEAKSLLSGLLAKDPRNRLGGGQDDVKEIQAHPFFASINWTDLVQ 541

Query: 309 RKVEAPFIPKFRGSGDTSNFD-DYEEEEIRVSITEKCG 345
           +K+  PF P+     DT  FD ++  E + ++  +  G
Sbjct: 542 KKITPPFKPQVTSDTDTRYFDEEFTGESVELTPPDPTG 655
>18484
          Length = 635

 Score =  142 bits (357), Expect = 2e-34,   Method: Compositional matrix adjust.
 Identities = 66/159 (41%), Positives = 100/159 (62%), Gaps = 3/159 (1%)
 Frame = +1

Query: 128 EMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFG 187
           ++   +++ G+F EP A FYAA+I +   +LH   +IYRDLK +N+++D +G+I++ DFG
Sbjct: 1   DLMYRIQQEGKFKEPVAAFYAAEIAVGLFFLHDQGIIYRDLKLDNVMLDSEGHIKIADFG 180

Query: 188 FAKRV---KGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQP 244
             K        T T CGTP+Y+APEI+L + Y+K+VDWWA GVL++EM AG PPF  +  
Sbjct: 181 MCKEGMTGDATTRTFCGTPDYIAPEIVLYQPYSKSVDWWAYGVLLFEMLAGQPPFDGEDE 360

Query: 245 IQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFG 283
            +++  I    V +P   S +   L + LL  + TKR G
Sbjct: 361 DELFSSITDHNVSYPKAMSREAVSLCKGLLMKNPTKRLG 477
>27405
          Length = 532

 Score =  120 bits (301), Expect = 8e-28,   Method: Compositional matrix adjust.
 Identities = 64/177 (36%), Positives = 107/177 (60%), Gaps = 7/177 (3%)
 Frame = -3

Query: 54  SFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEH-TLNEKRILQAVEF----PFLVRLE 108
            FG V   +   T + YAMK LDK+++ K+K  E   LNE+ +L  V      PF+V + 
Sbjct: 530 GFGEVYGCRKADTGKMYAMKCLDKKRI-KMKGGETLALNERIMLSLVSTGEGSPFIVCMT 354

Query: 109 YSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDL 168
           Y+F+    L  +++ + GG++  HL + G F+E   RFYAA+++L  E++HS  ++YRDL
Sbjct: 353 YAFQTPEKLCFILDLMNGGDLHYHLSQHGVFTEKEVRFYAAEVMLGLEHMHSRFVVYRDL 174

Query: 169 KPENLLIDHQGYIQVTDFGFAKRV-KGRTWTLCGTPEYLAPEIIL-SKGYNKAVDWW 223
           KP N+L+D  G+++++D G A    K +     GT  Y+APE+++  + Y+ + DW+
Sbjct: 173 KPANILLDENGHVRISDLGLACDFSKKKPHASVGTHGYMAPEVLMKGQAYDSSADWF 3
>00486
          Length = 797

 Score =  120 bits (301), Expect = 9e-28,   Method: Compositional matrix adjust.
 Identities = 54/134 (40%), Positives = 81/134 (60%)
 Frame = -2

Query: 196 TWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGK 255
           T T CGT EY+APEI+   G+ KAVDWW+LG L+Y+M  G PPF A+   +  +KI+ GK
Sbjct: 787 THTFCGTIEYMAPEILTRTGHGKAVDWWSLGALMYDMLTGSPPFTAENRKKTIDKILKGK 608

Query: 256 VRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDWIAIYQRKVEAPF 315
           +  P + +++ + L++ LL+ +  +R G   +    IK H++F  T+W  +  R+ E PF
Sbjct: 607 LNLPPYLTNEARGLIKKLLRKNPAERLGGGHDDSGPIKDHQFFRNTNWALLALRRAEPPF 428

Query: 316 IPKFRGSGDTSNFD 329
            P      DTS FD
Sbjct: 427 RPNVTSDEDTSQFD 386
>31885
          Length = 529

 Score =  115 bits (288), Expect = 3e-26,   Method: Compositional matrix adjust.
 Identities = 58/162 (35%), Positives = 95/162 (58%), Gaps = 7/162 (4%)
 Frame = -2

Query: 95  ILQAVEFPFLVRLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLT 154
           +L  ++ PFLV L Y+F+D  +L+MV++   GG++  H+++   F E   +FY  Q+ L 
Sbjct: 513 MLTRLDHPFLVNLWYAFQDEEDLFMVVDLFLGGDLRYHMQQEVSFREDCVKFYLCQLALV 334

Query: 155 FEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGR--TWTLCGTPEYLAPE--- 209
            +YL S  +++RD+KP+N+L+D QG+  VTDF  A +++      +  GT  Y+APE   
Sbjct: 333 LDYLRSQKIVHRDIKPDNILLDEQGHCHVTDFNIATQLEDDELATSTSGTRPYMAPEVYG 154

Query: 210 --IILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYE 249
             I   +GY   VDWW+LGV ++E+     PF       ++E
Sbjct: 153 VAINERRGYGFPVDWWSLGVSLFELLKKRRPFSVHSNTSLHE 28
>15910
          Length = 1361

 Score =  114 bits (284), Expect = 7e-26,   Method: Compositional matrix adjust.
 Identities = 57/164 (34%), Positives = 96/164 (58%), Gaps = 9/164 (5%)
 Frame = +2

Query: 128 EMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLL---IDHQGYIQVT 184
           E+F  +   G+++E  A    + I+   +Y+H+  +++RDLKPENLL   +     +++ 
Sbjct: 422 ELFDRIVTRGQYTEKDAARAISDILHGVQYIHANGVVHRDLKPENLLYECMTDDSKLKLA 601

Query: 185 DFGFAKRVKGRTW--TLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFAD 242
           DFG ++ ++      T+CGTP Y APE++    Y  +VD W++GV+ Y +  GY PFFA+
Sbjct: 602 DFGLSRIIEPEVQMSTVCGTPGYCAPEVLKGDKYTPSVDMWSVGVIAYILLCGYEPFFAE 781

Query: 243 QPIQIYEKIVSGKVRFP----SHFSSDLKDLLRNLLQVDLTKRF 282
              ++Y KI+ G+ +F     S  S + KD++R LL +D  KR 
Sbjct: 782 NEFEMYRKIIKGEYKFDEEYWSEISENAKDVVRKLLVIDPKKRL 913
>12721
          Length = 821

 Score =  108 bits (270), Expect = 3e-24,   Method: Compositional matrix adjust.
 Identities = 72/247 (29%), Positives = 126/247 (51%), Gaps = 6/247 (2%)
 Frame = +1

Query: 41  LEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVE 100
           L+DF +   +G GS G V +   +   Q  A+K +D +K    ++ E   NE  +++   
Sbjct: 94  LDDFMK---IGEGSTGIVCIATSRDGRQM-AVKKMDLRK---QQRRELLFNEVVVMRDYH 252

Query: 101 FPFLVRLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHS 160
            P +V +  S+  N  L++VME++ GG + + +    R  E          +    +LH+
Sbjct: 253 HPNIVEMYNSYLVNDELWVVMEFMEGGAL-TDIVTNNRMDEVQIATVCRACLKALAFLHA 429

Query: 161 LDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKG---RTWTLCGTPEYLAPEIILSKGYN 217
             +I+RD+K +++L+ H G +++ DFGF  +V     +  +L GTP ++APE+I    Y 
Sbjct: 430 NGVIHRDIKSDSILLSHDGKVKLXDFGFCAQVTQDLQKRKSLVGTPYWMAPEVISRLPYG 609

Query: 218 KAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKI---VSGKVRFPSHFSSDLKDLLRNLL 274
             VD W+LG+++ EM    PPFF + P+Q   +I      K+R     S  L+  +  +L
Sbjct: 610 PEVDIWSLGIMVMEMIDAEPPFFNEPPLQAMRRIRDMPPPKLRNTHKISPRLQGFIDRML 789

Query: 275 QVDLTKR 281
             D  +R
Sbjct: 790 VRDPHQR 810
>18921
          Length = 697

 Score =  105 bits (261), Expect = 3e-23,   Method: Compositional matrix adjust.
 Identities = 66/210 (31%), Positives = 107/210 (50%), Gaps = 4/210 (1%)
 Frame = +2

Query: 35  PPSNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKR 94
           PP +     F+    LG GS+G V    HK T Q  A+K     +V     ++  + E  
Sbjct: 20  PPEDV----FDILGKLGEGSYGSVFKSLHKETGQVLAIK-----QVPVDTDLQEIIKEIS 172

Query: 95  ILQAVEFPFLVRLEYSFKDNSNLYMVMEYVPGGEMFSHLR-RIGRFSEPHARFYAAQIVL 153
           I+Q  +  ++V+   S+  N++L++VMEY   G +   +R R     E          + 
Sbjct: 173 IMQQCDSKYIVKYYGSYFKNTDLWIVMEYCGAGSVSDIMRLRNKTLVEREIATILYYTLK 352

Query: 154 TFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVK---GRTWTLCGTPEYLAPEI 210
              YLHS   I+RD+K  N+L++++G+ ++ DFG A ++     +  T+ GTP ++APE+
Sbjct: 353 GLXYLHSRRKIHRDIKAGNILLNNEGHAKLADFGVAGQLTDTMAKRNTVIGTPYWMAPEV 532

Query: 211 ILSKGYNKAVDWWALGVLIYEMAAGYPPFF 240
           I   GY+   D W+LG+   EMA G PP  
Sbjct: 533 IQEIGYDCVADIWSLGITALEMAEGKPPVM 622
>09606
          Length = 1300

 Score =  103 bits (258), Expect = 7e-23,   Method: Compositional matrix adjust.
 Identities = 69/275 (25%), Positives = 123/275 (44%), Gaps = 33/275 (12%)
 Frame = -3

Query: 41   LEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVE 100
            +E+F   + LG G    +   + K T  + A+  ++K K  ++       N  R+   + 
Sbjct: 1118 MENFVLYEELGKGEHSIIYKGRRKGTINFVAIHCIEKCKRPEVT------NTVRMTHDIS 957

Query: 101  FPFLVRLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHS 160
             P +V+    ++ +++L++V+E   GG +   L +     E   R +   +V    Y+HS
Sbjct: 956  HPNVVQFHEWYETSNHLWLVVELCTGGSLADILAQDHHLPETSIRDFGIHLVTGLHYIHS 777

Query: 161  LDLIYRDLKPENLLIDHQGYIQVTDFGFAK-------------RVKGRTWTL-------- 199
            L +++ DL+P  +L+D  G ++  DFG +K                G  W +        
Sbjct: 776  LGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEAGDQWNIQSAEEMMK 597

Query: 200  ----CGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGK 255
                 G+P Y+APE+      +   D WALG + YEM +G+PPF  +      +K+++ +
Sbjct: 596  QVPTSGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFSGHPPFLGETYDITKDKVLNKE 417

Query: 256  VRFPSHFSSDLK--------DLLRNLLQVDLTKRF 282
               P    S L         +LL +LLQ D T+R 
Sbjct: 416  FPLPKVKGSRLSAKPSPEFLNLLESLLQKDSTRRL 312
>26560
          Length = 398

 Score =  100 bits (248), Expect = 1e-21,   Method: Compositional matrix adjust.
 Identities = 43/114 (37%), Positives = 75/114 (65%), Gaps = 2/114 (1%)
 Frame = -1

Query: 128 EMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFG 187
           ++  HL + G F+E   RFYAA+++L  E++HS  ++YRDLKP N+L+D  G+++++D G
Sbjct: 398 DLHYHLSQHGVFTEKEVRFYAAEVMLGLEHMHSRFVVYRDLKPANILLDENGHVRISDLG 219

Query: 188 FAKRV-KGRTWTLCGTPEYLAPEIIL-SKGYNKAVDWWALGVLIYEMAAGYPPF 239
            A    K R     GT  Y+APE+++  + Y+ + DW++ G ++Y++  G+ PF
Sbjct: 218 LACDFSKKRPHASVGTHGYMAPEVLMKGQSYDSSADWFSFGCMLYKLLKGHSPF 57
>01707
          Length = 757

 Score = 99.4 bits (246), Expect = 2e-21,   Method: Compositional matrix adjust.
 Identities = 65/201 (32%), Positives = 107/201 (53%), Gaps = 6/201 (2%)
 Frame = +1

Query: 41  LEDFERKKTLGTGSFGRVMLVKHKATEQYYAMK-ILDKQKVVKLKQIEHTLNEKRILQAV 99
           +E +E+   +G GS+G V   ++K T Q  A+K  ++ +    +K+I   + E R+L+ +
Sbjct: 61  MEKYEKIGKIGEGSYGVVFKCRNKETSQLVAIKKFVESEDDPLIKKI--AMREIRMLKQL 234

Query: 100 EFPFLVRLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGR-FSEPHARFYAAQIVLTFEYL 158
           + P LVRL   F+    L++V +YV    + + L R  R   EP  +    Q +L   + 
Sbjct: 235 KHPNLVRLIEVFRRKKRLHLVFDYV-DHTLLNELDRYPRGLPEPMVKRIIYQTLLAVNFC 411

Query: 159 HSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKG---RTWTLCGTPEYLAPEIILSKG 215
           H  + I+RD+KPEN+LI  QG +++ DFGFA+ + G          T  Y APE+++   
Sbjct: 412 HQYNTIHRDVKPENILITRQGQVKLCDFGFARILTGPGDEYTDYVATRWYRAPELLVGDT 591

Query: 216 -YNKAVDWWALGVLIYEMAAG 235
            Y   VD WA+G +  E+  G
Sbjct: 592 QYGPPVDVWAIGCVFAELLTG 654
>14420
          Length = 528

 Score = 99.4 bits (246), Expect = 2e-21,   Method: Compositional matrix adjust.
 Identities = 49/163 (30%), Positives = 89/163 (54%), Gaps = 3/163 (1%)
 Frame = +2

Query: 87  EHTLNEKRILQAVEFPFLVRLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARF 146
           E  +NE  +++  + P +V    S+     L++VME++ GG +   +       E     
Sbjct: 35  ELIINEILVMRENQNPNIVNYLDSYLVGEELWVVMEFLAGGSLTDVVTETC-MDEGQIAA 211

Query: 147 YAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRV---KGRTWTLCGTP 203
              + +   E+LH   +I+RD+K +N+L+   G +++TDFGF  ++   + +  T+ GTP
Sbjct: 212 VCRECLQALEFLHENQVIHRDIKSDNILLGMDGSVKLTDFGFCAQLSPEQSKRSTMVGTP 391

Query: 204 EYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQ 246
            ++APE++  K Y   VD W+LGV+  EM  G PP+  + P++
Sbjct: 392 YWMAPEVVTRKQYGPTVDIWSLGVMCIEMIEGEPPYLNENPLR 520
>00300
          Length = 2318

 Score = 97.8 bits (242), Expect = 5e-21,   Method: Compositional matrix adjust.
 Identities = 70/249 (28%), Positives = 119/249 (47%), Gaps = 11/249 (4%)
 Frame = -1

Query: 44   FERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVEFPF 103
            ++R   +G G FG+V    + +T +  A+K +  Q    L+Q+    +E +I + ++   
Sbjct: 1652 WQRGNKIGEGQFGKVYTAVNMSTGELMALKEMKFQPN-DLQQLREMCDEIKIFEGIQHEN 1476

Query: 104  LVRLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDL 163
            LV+          + M MEY   G +     ++G   E   R Y  +IVL   +LH   +
Sbjct: 1475 LVKYYGVEVHKDEMLMFMEYCDTGTI-EEAAKMG-LPEYLIRRYTREIVLAVNHLHENSI 1302

Query: 164  IYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRT------WTLCGTPEYLAPEIILSK--- 214
            ++RD+K  N+ +   G++++ DFG + ++K  T        L GT  Y+APE+       
Sbjct: 1301 VHRDIKGANIFLTSNGHVKLGDFGCSVKLKSHTTMPGEFHNLVGTTAYMAPEVFTQNDQG 1122

Query: 215  GYNKAVDWWALGVLIYEMAAGYPPFF-ADQPIQIYEKI-VSGKVRFPSHFSSDLKDLLRN 272
            GY +A D W+LG ++ EMA G  P+   D   QI  K+ +  K   P   S + K  L  
Sbjct: 1121 GYGRAADIWSLGCVVIEMATGKRPWHDLDNNYQIMYKVGIGHKPAVPDSLSVEGKHFLDL 942

Query: 273  LLQVDLTKR 281
            ++  D  +R
Sbjct: 941  IMCHDPAQR 915
>18663
          Length = 600

 Score = 95.9 bits (237), Expect = 2e-20,   Method: Compositional matrix adjust.
 Identities = 50/141 (35%), Positives = 75/141 (53%), Gaps = 10/141 (7%)
 Frame = +2

Query: 198 TLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPF----FADQPIQ-----IY 248
           T CGTP Y+APEI+  + Y  +VDWWALGVL+YEM AG  PF     ++ P Q     ++
Sbjct: 5   TFCGTPNYIAPEILRGEDYGFSVDWWALGVLLYEMLAGRSPFDIAGASENPDQNTEDYLF 184

Query: 249 EKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFG-NLKNGVSDIKTHKWFATTDWIAIY 307
           + I+   +R P   S     +L+  L  +   R G + ++   DI  H +F   DW  + 
Sbjct: 185 QVILEKTIRIPRSLSVKAASVLKGFLNKNPADRLGCHRESAFMDIVNHPFFKVIDWEMLE 364

Query: 308 QRKVEAPFIPKFRGSGDTSNF 328
           +++V  PF P+     D +NF
Sbjct: 365 RKQVSPPFKPRLDSDRDLANF 427
>26156
          Length = 479

 Score = 84.0 bits (206), Expect(2) = 6e-20,   Method: Compositional matrix adjust.
 Identities = 43/108 (39%), Positives = 67/108 (62%), Gaps = 1/108 (0%)
 Frame = -1

Query: 40  GLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQ-A 98
           GL DF   + +G GS+ +V+ V+HK T++ YAMK++ K+ V   + I+    EK + + A
Sbjct: 395 GLTDFLLLRVIGRGSYAKVLQVEHKRTKRIYAMKVIKKELVNDDEDIDWVQTEKHVFETA 216

Query: 99  VEFPFLVRLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARF 146
             +PFLV L   F+  S L+ V+E+V GG++  H++R  R  E HARF
Sbjct: 215 TNYPFLVGLHSCFQSESRLFFVIEFVNGGDLMFHMQRQRRLPEEHARF 72

 Score = 30.8 bits (68), Expect(2) = 6e-20,   Method: Compositional matrix adjust.
 Identities = 12/24 (50%), Positives = 17/24 (70%)
 Frame = -3

Query: 146 FYAAQIVLTFEYLHSLDLIYRDLK 169
           FY+A+I L   +LH   ++YRDLK
Sbjct: 75  FYSAEICLALNFLHKRGIVYRDLK 4
>13592
          Length = 980

 Score = 93.2 bits (230), Expect = 1e-19,   Method: Compositional matrix adjust.
 Identities = 68/249 (27%), Positives = 119/249 (47%), Gaps = 12/249 (4%)
 Frame = +2

Query: 50  LGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVEFPFLVRLEY 109
           +G G FG+V    +  T +  AMK +  Q   + + +++   E +IL+ ++   LVR   
Sbjct: 8   IGQGRFGKVYTAVNNNTGELMAMKEIAIQPG-ETRALKNVAEELKILEGIKHKNLVRYYG 184

Query: 110 SFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLK 169
                  L + ME    G + S +   G   E  +R + AQ++     LH   +++RD+K
Sbjct: 185 IEVHREELLIFMELCSEGTLESLVELTGGLPEALSRRFTAQLLSGVAELHKHGIVHRDIK 364

Query: 170 PENL-LIDHQGYIQVTDFGFAKRVKGRTWT------LCGTPEYLAPEIIL---SKGYNKA 219
             N+ L+D    +++ DFG A +++  T          GT  Y+APE+     S G+ + 
Sbjct: 365 TANIFLVDGSNSLKLGDFGSAVKIQAHTTVPGELQGYVGTQAYMAPEVFTKTNSDGHGRL 544

Query: 220 VDWWALGVLIYEMAAGYPPFFA-DQPIQIYEKIVSG-KVRFPSHFSSDLKDLLRNLLQVD 277
            D W++G ++ EMA+G  P+   D   QI  K+  G K + P   S +  D + + LQ D
Sbjct: 545 ADIWSVGCVVVEMASGKRPWAQFDSNFQIMFKVGMGEKPQAPESLSQEGHDFIDHCLQHD 724

Query: 278 LTKRFGNLK 286
             +R   ++
Sbjct: 725 PKQRLSAIE 751
>01392
          Length = 1806

 Score = 92.8 bits (229), Expect = 2e-19,   Method: Compositional matrix adjust.
 Identities = 60/199 (30%), Positives = 89/199 (44%), Gaps = 35/199 (17%)
 Frame = -1

Query: 137  GRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQG---YIQVTDFGFAKRVK 193
            G   E  A      I    ++LHS  + +RDLKPEN+L +H      +++ DF  A  + 
Sbjct: 1806 GHLCEREASLVVRHIARALDFLHSKGIAHRDLKPENILCEHLDDVVPVKICDFDLASGIS 1627

Query: 194  G--------RTWTLCGTPEYLAPEIIL-----SKGYNKAVDWWALGVLIYEMAAGYPPFF 240
                        T  G+ EY+APE++      S  Y+K  D W+LG+++Y M  GYPPF+
Sbjct: 1626 CDGDGTKTPELLTPVGSAEYMAPEVVDAWVGDSFSYDKRCDLWSLGIILYIMLCGYPPFY 1447

Query: 241  A---------------DQPIQIYEKIVSGKVRFPSH----FSSDLKDLLRNLLQVDLTKR 281
                            D    ++  I  G  +FPS      SS  KDL+R+LL  +  KR
Sbjct: 1446 GQCGEDCGWNRGEACHDCQDMLFNSIQDGHYKFPSQEWTSISSSAKDLIRHLLVREPRKR 1267

Query: 282  FGNLKNGVSDIKTHKWFAT 300
            +       +D+  H W  T
Sbjct: 1266 Y-----SAADVLKHPWICT 1225
>06405
          Length = 1965

 Score = 85.1 bits (209), Expect = 4e-17,   Method: Compositional matrix adjust.
 Identities = 71/243 (29%), Positives = 113/243 (46%), Gaps = 8/243 (3%)
 Frame = +1

Query: 47  KKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVEFPFLVR 106
           K  LG G +G V     K   +  A+K L K+  + L      L E  I++ ++ P LV+
Sbjct: 274 KHRLGGGQYGDVYEAMWKRYNKIVAVKTL-KEDTMALNDF---LEEAAIMKEMKHPNLVQ 441

Query: 107 LEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSE-PHARFY-AAQIVLTFEYLHSLDLI 164
           L          Y+V E++P G +  +LR   R    P A  Y A QI     YL + + I
Sbjct: 442 LLGVCTREPPFYIVTEFMPHGNLLDYLRSSTREENGPTALMYMATQIASGMAYLETKNFI 621

Query: 165 YRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTWTL-CGTP---EYLAPEIILSKGYNKAV 220
           +RDL   N L+     ++V DFG A+ +K  T+T   G     ++ APE +    ++   
Sbjct: 622 HRDLAARNCLVADSNMVKVADFGLARLMKDDTYTAHIGAKFPIKWTAPEGLAFNRFSTRS 801

Query: 221 DWWALGVLIYEMAA-GYPPFFADQPIQIYEKIVSG-KVRFPSHFSSDLKDLLRNLLQVDL 278
           D WA GVL++E+A  G  P+   +  ++Y  +  G ++  P    +D+  L+    Q D 
Sbjct: 802 DIWAFGVLLWELATYGMSPYPGVELTEVYHLLERGYRMERPPGTPADVYILMLKCWQWDP 981

Query: 279 TKR 281
             R
Sbjct: 982 KDR 990
>01060
          Length = 1800

 Score = 84.3 bits (207), Expect = 7e-17,   Method: Compositional matrix adjust.
 Identities = 67/234 (28%), Positives = 110/234 (47%), Gaps = 21/234 (8%)
 Frame = +1

Query: 39  AGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIE-----HTLNEK 93
             L D    + +G G++G V   +H+AT +  AMK       ++L+  E       + E 
Sbjct: 64  TALSDLTDFQKIGEGTYGVVYKCRHRATGRKLAMK------KIRLRGSEDGVPSSAIREI 225

Query: 94  RILQAVEFPFLVRLEYSFKDNSNLYMVMEYV-----------PGGEMFSHLRRIGRFSEP 142
            +L+ +    +V LE    ++  L++V E++           P G +    RR+      
Sbjct: 226 AMLRELRHTNIVCLEDVIMEDERLFLVFEFLSMDLKMYIDKFPEGVVLD--RRL------ 381

Query: 143 HARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKR----VKGRTWT 198
             + Y  QIV    + H   +++RDLKP+NLLI+H G I++ DFG A+     V+  T  
Sbjct: 382 -VKSYVFQIVTGIXFCHQRRIVHRDLKPQNLLINHTGAIKIADFGMARTFALPVRAYTHE 558

Query: 199 LCGTPEYLAPEIIL-SKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKI 251
           +  T  Y APEI++ +  Y+  VD W++G +  +M    P F  D  I    KI
Sbjct: 559 VV-TLWYRAPEILMGASKYSTPVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKI 717
>17975
          Length = 449

 Score = 84.0 bits (206), Expect = 8e-17,   Method: Compositional matrix adjust.
 Identities = 48/137 (35%), Positives = 80/137 (58%), Gaps = 2/137 (1%)
 Frame = +3

Query: 55  FGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVEFPFLVRLEYSFKDN 114
           F  V L +H  T +  A+K++DK K+ ++ +  H   E R ++ V+ P +VRL       
Sbjct: 6   FAVVKLARHVFTGEKVAVKVIDKTKLDEVSR-SHLFQEVRCMKLVQHPNVVRLYEVIDTQ 182

Query: 115 SNLYMVMEYVPGGEMFSH-LRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENL 173
           + LY+++E   GG+M+ + +R  G   E  A+ Y  QIV    Y H L +++RDLKPEN+
Sbjct: 183 TKLYLILELGDGGDMYDYIMRHSGGLEEKLAKRYFRQIVEAISYCHKLHVVHRDLKPENV 362

Query: 174 L-IDHQGYIQVTDFGFA 189
           +  +  G +++TDFGF+
Sbjct: 363 VFFEKPGLVKLTDFGFS 413
>13066
          Length = 551

 Score = 83.6 bits (205), Expect = 1e-16,   Method: Compositional matrix adjust.
 Identities = 48/164 (29%), Positives = 85/164 (51%), Gaps = 8/164 (4%)
 Frame = +3

Query: 71  AMKILDKQKVVKLKQIEHTL-NEKRILQAVEFPFLVRLEYSFKDNSNLYMVMEYVPGGEM 129
           A KI+DK+K   +  +E     E  +L  ++ P+++++    +     ++ M +   G++
Sbjct: 63  ACKIIDKEKA-PVDFVEKFFPRELDLLTKLDHPYIIQIHSILQRXPKNFIFMRFAERGDL 239

Query: 130 FSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFA 189
            ++++ +G   E  A+ +  Q+     YLHS D+ +RDLK EN+L+     +++ DFGFA
Sbjct: 240 LTYIQEVGFVKEKQAKIWFYQMTTALNYLHSYDVAHRDLKCENILLSSHFNVKLADFGFA 419

Query: 190 KRV------KGRTWTLCGTPEYLAPEIILSKGYN-KAVDWWALG 226
                    K  + T CG+  Y APEI+    Y  K  D W+LG
Sbjct: 420 CACITESGEKYMSRTYCGSAAYAAPEIVYGAPYAPKVADAWSLG 551
>21079
          Length = 878

 Score = 81.3 bits (199), Expect = 6e-16,   Method: Compositional matrix adjust.
 Identities = 47/142 (33%), Positives = 76/142 (53%), Gaps = 5/142 (3%)
 Frame = +1

Query: 102 PFLVRLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIG-RFSEPHARFYAAQIVLTFEYLHS 160
           P L+ L  +F+    + +VME+V  GE+F  + R     +E     +  QI     Y+H+
Sbjct: 4   PKLLMLWDAFEAPRTMVLVMEFVGAGELFERVIRDDFVLTERDCVHFVRQICSGVGYMHT 183

Query: 161 LDLIYRDLKPENLLI--DHQGYIQVTDFGFAKRVK--GRTWTLCGTPEYLAPEIILSKGY 216
             +++ DLKPEN+L   D+   I++ DFG A+  K       L GTPE++APE++     
Sbjct: 184 QSILHLDLKPENVLCVSDNSNQIKIIDFGLARFYKPGDSLQVLFGTPEFIAPEVVNYDEI 363

Query: 217 NKAVDWWALGVLIYEMAAGYPP 238
           N   D W++GV+ Y + +G  P
Sbjct: 364 NFTTDMWSIGVICYILLSGLSP 429
>17722
          Length = 680

 Score = 79.3 bits (194), Expect = 2e-15,   Method: Compositional matrix adjust.
 Identities = 38/106 (35%), Positives = 59/106 (55%)
 Frame = -3

Query: 220 VDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLT 279
           VDWW  GV++YEM  G  PF+      ++E I+   V+FP + S + K LL  LL  +  
Sbjct: 678 VDWWGTGVVMYEMMCGRLPFYNRDHDVLFELILLQNVKFPRNLSEEAKTLLSGLLAKNPK 499

Query: 280 KRFGNLKNGVSDIKTHKWFATTDWIAIYQRKVEAPFIPKFRGSGDT 325
           +R G  +  V++IKTH +F   +W  +  +K+  P+ P  + S DT
Sbjct: 498 RRLGGSEADVTEIKTHPFFQCINWDDLAAKKITPPWKPDVKSSWDT 361
>21433
          Length = 590

 Score = 77.4 bits (189), Expect = 7e-15,   Method: Compositional matrix adjust.
 Identities = 46/130 (35%), Positives = 69/130 (53%), Gaps = 1/130 (0%)
 Frame = +2

Query: 147 YAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRV-KGRTWTLCGTPEY 205
           Y  Q+    EY H   +I+RD+KPENLL+  +G +++ DFG++      R  T+CGT +Y
Sbjct: 182 YIYQLSSALEYCHYRKVIHRDIKPENLLLGLKGDLKIADFGWSVHAPSSRRTTMCGTLDY 361

Query: 206 LAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSD 265
           L PE++  K +++ VD W+LGVL YE   G PP                    PS  +  
Sbjct: 362 LPPEMVEGKTHDENVDLWSLGVLCYEFLVGTPPLRPSPTRPPTPASPRWTSGSPSIVTPG 541

Query: 266 LKDLLRNLLQ 275
            +DL+  LL+
Sbjct: 542 ARDLISKLLR 571
>01756
          Length = 1858

 Score = 76.3 bits (186), Expect = 2e-14,   Method: Compositional matrix adjust.
 Identities = 56/211 (26%), Positives = 103/211 (48%), Gaps = 17/211 (8%)
 Frame = -3

Query: 44   FERKKTLGTGSFGRVMLVKHKATEQYYAMK--ILDKQK----VVKLKQIE--HTLNEKRI 95
            +E+   +G G+FG V   + K T+Q  AMK  ++D +K    +  L++I+    LN + +
Sbjct: 1736 YEKLAKIGQGTFGEVFKARCKKTKQVVAMKKVLMDNEKEGFPITALREIKILQLLNHENV 1557

Query: 96   LQAVEFPFLVRLEYSFKDNSNLYMVMEYVPG--GEMFSHLRRIGRFSEPHARFYAAQIVL 153
            +  +E     +   + +  S  Y+V E+       + S++  +  F+ P  +    Q++ 
Sbjct: 1556 VDLIEI-CSTKATSANRYKSMFYLVFEFCEHDLAGLLSNMSVV--FNLPEIKEVMKQLMN 1386

Query: 154  TFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAK------RVKGRTWTLCGTPEYLA 207
               Y+H   +++RD+K  N+LI  QG +++ DFG A+      R   R      T  Y  
Sbjct: 1385 GLYYIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRVVTLWYRP 1206

Query: 208  PEIILS-KGYNKAVDWWALGVLIYEMAAGYP 237
            PE++L  + Y+ A+D W  G ++ EM    P
Sbjct: 1205 PELLLGDRNYSTAIDQWGAGCIMAEMWTRNP 1113
>00392
          Length = 668

 Score = 75.5 bits (184), Expect = 3e-14,   Method: Compositional matrix adjust.
 Identities = 51/177 (28%), Positives = 101/177 (57%), Gaps = 14/177 (7%)
 Frame = +3

Query: 92  EKRILQAVEFPFLVRL-----EYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARF 146
           E  +L+ ++ P +VR      E++ ++   + +V E +  G + ++L+R   F +P+ + 
Sbjct: 81  EAEMLKELQHPNIVRFFDYWEEHNHRNRKVIILVTELMTSGTLKTYLKR---FKKPNVKI 251

Query: 147 ---YAAQIVLTFEYLHSLD--LIYRDLKPENLLIDH-QGYIQVTDFGFAKRVKGRTW--T 198
              +  Q++    +LH+    +I+RDLK +N+ I    G +++ D G A  +K +++  +
Sbjct: 252 LKNWCRQVLKGLYFLHTRTPPVIHRDLKCDNIFITGPTGSVKIGDLGLAT-LKNQSFAKS 428

Query: 199 LCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAG-YPPFFADQPIQIYEKIVSG 254
           + GTPE++APE+   + Y++AVD +A G+ + EMA+  YP        QIY+++ SG
Sbjct: 429 VIGTPEFMAPEM-YEEHYDEAVDVYAFGMCMLEMASSEYPYSECSNAAQIYKRVTSG 596
>01718
          Length = 959

 Score = 73.9 bits (180), Expect = 9e-14,   Method: Compositional matrix adjust.
 Identities = 60/212 (28%), Positives = 103/212 (48%), Gaps = 15/212 (7%)
 Frame = +3

Query: 41  LEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVE 100
           L+DF  +K +G G F  V  V H+ T Q  A+K+             + L E ++L  ++
Sbjct: 147 LDDFICEK-IGAGFFSEVFKVTHRITGQVMALKM-----NTMTSNRHNMLREVQLLNRLQ 308

Query: 101 FPFLVRLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTF----- 155
              ++R          L+ + EY+P G +   L +     +     +  +I LT      
Sbjct: 309 HANILRFMGVCVHEGQLHALTEYIPSGNLEQLLEK-----KDEELPWTQRIQLTLGLARG 473

Query: 156 -EYLHSLDLIYRDLKPENLLI---DHQGYIQV-TDFGFAKRV-----KGRTWTLCGTPEY 205
            +YLHS   I+RDL  +N+LI   D+ GY  V  DFG A ++     K +  T+ G+P +
Sbjct: 474 LDYLHSTRFIHRDLTSKNILIRREDNHGYHAVIADFGLATKIPDPLDKEKLPTV-GSPYW 650

Query: 206 LAPEIILSKGYNKAVDWWALGVLIYEMAAGYP 237
           +APE++    YN+  D +++G+++ E+ A  P
Sbjct: 651 MAPEVLNGHFYNERADLFSVGIIMCEITARIP 746
>09007
          Length = 1440

 Score = 71.2 bits (173), Expect = 6e-13,   Method: Compositional matrix adjust.
 Identities = 58/220 (26%), Positives = 100/220 (45%), Gaps = 16/220 (7%)
 Frame = -1

Query: 48  KTLGTGSFGRV---MLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVEFPFL 104
           K+LG G FG V   +       +   A+K L K K+ K  Q    L E  I+Q ++   +
Sbjct: 861 KSLGQGHFGTVRQAIWTAESGEKVQVAVKCLSKDKIHKDGQ--EFLKETAIMQMLDHENI 688

Query: 105 VRLEYSFKDN-SNLYMVMEYVPGGEMFSHLRRIGR---FSEPHARFYAAQIVLTFEYLHS 160
           VR+     DN +++ +V E  P   +   ++ +     FS P    ++ Q+     YL S
Sbjct: 687 VRVYGVVMDNGADIMLVTELAPMRSLLECVKEVSARVDFSVPRLCDFSQQVCDGMSYLES 508

Query: 161 LDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKG--------RTWTLCGTPEYLAPEIIL 212
             L++RDL   N+L+  +  ++++D G +  +          +T  L     + APE   
Sbjct: 507 KRLVHRDLAARNILLFSKSKVKISDVGVSGALGAGKEYYQSQQTIHLQNAVAWCAPESFR 328

Query: 213 SKGYNKAVDWWALGVLIYE-MAAGYPPFFADQPIQIYEKI 251
           +  ++ A D WA GVL++E    G+ P+      QI E +
Sbjct: 327 NLCFSSASDVWAFGVLLWEFFTHGFQPWAGLNGQQIMEAV 208
>27546
          Length = 426

 Score = 70.5 bits (171), Expect = 1e-12,   Method: Compositional matrix adjust.
 Identities = 30/99 (30%), Positives = 57/99 (57%)
 Frame = -1

Query: 92  EKRILQAVEFPFLVRLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQI 151
           E  IL  ++ P ++++    +    +++ M Y   G+M SH+++ G   E   + +  Q+
Sbjct: 330 ELEILTRLDHPNIIQIHSILQRGPKIFIFMRYAEKGDMLSHIKKTGPIDEAQTKVWFFQM 151

Query: 152 VLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAK 190
               +YLHS D+ +RDLK EN+L+  +  +++ DFGFA+
Sbjct: 150 AKALQYLHSHDIAHRDLKCENILLSKRLNVKIADFGFAR 34
>19094
          Length = 898

 Score = 69.7 bits (169), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 33/82 (40%), Positives = 53/82 (64%), Gaps = 3/82 (3%)
 Frame = +1

Query: 157 YLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVK---GRTWTLCGTPEYLAPEIILS 213
           YLHS   I+RD+K  N+L++++G+ ++ DFG A ++     +  T+ GTP ++APE+I  
Sbjct: 103 YLHSRRKIHRDIKAGNILLNNEGHAKLADFGVAGQLTDTMAKRNTVIGTPYWMAPEVIQE 282

Query: 214 KGYNKAVDWWALGVLIYEMAAG 235
            GY+   D W+LG+   EMA G
Sbjct: 283 IGYDCVADIWSLGITALEMAEG 348
>25019
          Length = 730

 Score = 68.2 bits (165), Expect = 5e-12,   Method: Compositional matrix adjust.
 Identities = 31/59 (52%), Positives = 42/59 (71%), Gaps = 3/59 (5%)
 Frame = +3

Query: 171 ENLLIDHQGYIQVTDFGFAKR-VKGR--TWTLCGTPEYLAPEIILSKGYNKAVDWWALG 226
           EN+L+D  G++++TDFG  K  + G   T T CGT EY+APEI+   G+ KAVDWW+LG
Sbjct: 261 ENVLLDKDGHVKLTDFGLCKEAITGTRVTHTFCGTIEYMAPEILTRTGHGKAVDWWSLG 437

 Score = 47.8 bits (112), Expect = 6e-06,   Method: Compositional matrix adjust.
 Identities = 23/74 (31%), Positives = 41/74 (55%), Gaps = 4/74 (5%)
 Frame = +1

Query: 214 KGYNKAVDW----WALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDL 269
           +G   A  W    W  G L+Y+M  G PPF A+   +  +KI+ GK+  P + +++ + L
Sbjct: 394 RGQGTARRWTGGVW--GALMYDMLTGSPPFTAENRKKTIDKILKGKLNLPPYLTNEARGL 567

Query: 270 LRNLLQVDLTKRFG 283
           ++ LL+ +  +R G
Sbjct: 568 IKKLLRKNPAERLG 609
>19761
          Length = 473

 Score = 67.4 bits (163), Expect = 7e-12,   Method: Compositional matrix adjust.
 Identities = 34/128 (26%), Positives = 67/128 (52%), Gaps = 3/128 (2%)
 Frame = -3

Query: 153 LTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGR---TWTLCGTPEYLAPE 209
           L + + H+  +++RDLKP+N+ +  +G +++ D G A+++ G      +  GT  YL+PE
Sbjct: 384 LNYMHTHTPVILHRDLKPQNIYVTEKGDVRLGDLGLARKLTGPADFATSQVGTIMYLSPE 205

Query: 210 IILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDL 269
           I+  + YN   D W+LG + Y++              + + +   K+  P H+S + +D 
Sbjct: 204 ILSQQPYNSKSDIWSLGCVFYDITGKKGSDEMGVMFLLVQVMGGRKLPLPDHYSQEFRDT 25

Query: 270 LRNLLQVD 277
           +  +L  D
Sbjct: 24  ISRMLTKD 1
>26711
          Length = 405

 Score = 67.4 bits (163), Expect = 8e-12,   Method: Compositional matrix adjust.
 Identities = 41/130 (31%), Positives = 69/130 (53%), Gaps = 9/130 (6%)
 Frame = -2

Query: 150 QIVLTFEYLHSLDLIYRDLKPENLLI--DHQGYIQVTDFGFAKRV--KGRTWTLCGTPEY 205
           Q++   +++H+  +++ DLKP NLL+  D    +Q+ DFG A+++     T+   GTP +
Sbjct: 392 QVLDILQHVHAQGVVHMDLKPSNLLLSGDKLDSVQLIDFGLARKLYPPQETFLNHGTPGF 213

Query: 206 LAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFP-----S 260
            +PE +  K  + A D W +GVL Y + +G  PF AD   +  +K  +    F      S
Sbjct: 212 TSPEALDVKPISTASDVWGVGVLAYILLSGQSPFQADSATESLKKTQTCDWSFDVCPSFS 33

Query: 261 HFSSDLKDLL 270
           + S D KD +
Sbjct: 32  NMSQDAKDFI 3
>11185
          Length = 473

 Score = 65.1 bits (157), Expect = 4e-11,   Method: Compositional matrix adjust.
 Identities = 43/163 (26%), Positives = 67/163 (41%), Gaps = 25/163 (15%)
 Frame = +1

Query: 145 RFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAK-------------R 191
           R +   +V    Y+HSL +++ DL+P  +L+D  G ++  DFG +K              
Sbjct: 10  RDFGIHLVTGLHYIHSLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFA 189

Query: 192 VKGRTWTL------------CGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPF 239
             G  W +             G+P Y+APE+      +   D WALG + YEM +G    
Sbjct: 190 EAGDQWNIQSAEEMMKQVPTSGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFSG---- 357

Query: 240 FADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRF 282
                            R  +  S +  +LL +LLQ D T+R 
Sbjct: 358 ----------------SRLSAKPSPEFLNLLESLLQKDSTRRL 438
>13212
          Length = 1067

 Score = 64.3 bits (155), Expect = 6e-11,   Method: Compositional matrix adjust.
 Identities = 46/182 (25%), Positives = 85/182 (46%), Gaps = 14/182 (7%)
 Frame = -1

Query: 139 FSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKR---VKGR 195
            +E    +   ++ +  ++LH   +I+RD+K  N+L+   G +++ DFG + +    + +
Sbjct: 989 MTEAQICYVCHEMCMALDFLHRHHVIHRDIKAGNVLLTIDGEVKLADFGVSAKNTQTQQK 810

Query: 196 TWTLCGTPEYLAPEIILSKG-----YNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEK 250
             T  GTP ++APE++L +      Y+   D W+LGV + E A   PP     P+++  K
Sbjct: 809 RDTFIGTPYWMAPEVVLCETLKDTPYDFKADIWSLGVTLIEFAQIEPPNKEMHPMRVLIK 630

Query: 251 IVSGK---VRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWF---ATTDWI 304
           I       +  P  ++   KD +   L  D      NL+   +++  H +      TD  
Sbjct: 629 IHKSDPPTLEKPKKWTKLFKDFIAKCLVKD-----PNLRPTAAELLEHPFMKRATATDKA 465

Query: 305 AI 306
           AI
Sbjct: 464 AI 459
>28638
          Length = 1458

 Score = 63.9 bits (154), Expect = 8e-11,   Method: Compositional matrix adjust.
 Identities = 32/100 (32%), Positives = 59/100 (59%), Gaps = 4/100 (4%)
 Frame = -1

Query: 144 ARFYAAQIVLTFEYLHS--LDLIYRDLKPENLLIDH--QGYIQVTDFGFAKRVKGRTWTL 199
            R +A Q+     +L +  +++I+ DLKPEN+L+ +  +  I++ DFG + ++  R +  
Sbjct: 831 TRKFAQQLCTALLFLATPEMNIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQY 652

Query: 200 CGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPF 239
             +  Y +PE++L   Y+ A+D W+LG ++ EM  G PP 
Sbjct: 651 IQSRFYRSPEVLLGVPYDLAIDMWSLGCILVEMHTGEPPL 532
>29581
          Length = 1278

 Score = 63.9 bits (154), Expect = 9e-11,   Method: Compositional matrix adjust.
 Identities = 45/148 (30%), Positives = 75/148 (50%), Gaps = 7/148 (4%)
 Frame = -2

Query: 112  KDNSNLYMVMEYVPGGEMFSHLRRI-GRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKP 170
            K   +L++VMEY    ++ S L  +   FSE   +    Q++    YLH   +I+RDLK 
Sbjct: 1139 KSLDSLFLVMEYC-EQDLASLLDNMPAPFSESQVKCIVLQLLKGLRYLHEAFIIHRDLKV 963

Query: 171  ENLLIDHQGYIQVTDFGFAKRVKGRTWTLCGTPE-----YLAPEIIL-SKGYNKAVDWWA 224
             NLL+  +G +++ DFG A+        +  TP+     Y APE++  SK ++ A+D W+
Sbjct: 962  SNLLMTDKGCVKIADFGLARNYGKPQKPM--TPKVVTLWYRAPELLFGSKTHSTAIDMWS 789

Query: 225  LGVLIYEMAAGYPPFFADQPIQIYEKIV 252
             G ++ E+    P       +Q  E I+
Sbjct: 788  AGCILGELLGHKPLMPGRSDLQQIELIM 705
>14126
          Length = 1265

 Score = 62.0 bits (149), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 52/213 (24%), Positives = 97/213 (45%), Gaps = 22/213 (10%)
 Frame = +3

Query: 42  EDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRI------ 95
           + +E    +G G++G V          Y A  + ++ + V +K+I     E+ +      
Sbjct: 189 QKYEEVAVIGNGAYGTV----------YKARDLRNQGEFVAMKRIRLNNTEEGMPMMAIR 338

Query: 96  -------LQAVEFPFLVRL----EYSFKDNS-NLYMVMEYVPGGEMFSHLRRIGR--FSE 141
                  L+  E P +VRL      +  D    L +V EY+   ++ ++L +        
Sbjct: 339 EISMLKQLEQYEHPNVVRLLDVSHNTITDREIRLNLVFEYIEH-DLATYLAKCPSPGLGP 515

Query: 142 PHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAK--RVKGRTWTL 199
              +    Q++   ++LHS  +++RDLKP+NLLI   G +++ DFG A+         T+
Sbjct: 516 DRIKDLMLQLLNGVDFLHSNRIVHRDLKPQNLLISKDGRLKLADFGLARIYSFHMALTTV 695

Query: 200 CGTPEYLAPEIILSKGYNKAVDWWALGVLIYEM 232
             T  Y +PE+++   Y  +VD W+ G +  E+
Sbjct: 696 VVTLWYRSPEVLMQAEYGTSVDIWSCGCIFAEL 794
>01966
          Length = 1735

 Score = 62.0 bits (149), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 54/188 (28%), Positives = 86/188 (45%), Gaps = 20/188 (10%)
 Frame = -1

Query: 61   VKHKATEQYYAMKILDKQKVVKLKQIE-----HTLNEKRILQAVEFPFLVRLEYSFKDNS 115
             +H+AT +  AMK       ++L+  E       + E  +L+ +    +V LE    ++ 
Sbjct: 1654 CRHRATGRKLAMK------KIRLRGSEDGVPSSAIREIAMLRELRHTNIVCLEDVIMEDE 1493

Query: 116  NLYMVMEYV-----------PGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLI 164
             L++V E++           P G +    RR+        + Y  QIV    + H   ++
Sbjct: 1492 RLFLVFEFLSMDLKMYIDKFPEGVVLD--RRL-------VKSYVFQIVTGINFCHQRRIV 1340

Query: 165  YRDLKPENLLIDHQGYIQVTDFG----FAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAV 220
            +RDLKP+NLLI+H G I++ DFG    FA  V+  T  +  T  Y APEI++  G     
Sbjct: 1339 HRDLKPQNLLINHTGAIKIADFGMARTFALPVRAYTHEVV-TLWYRAPEILM--GPQSTP 1169

Query: 221  DWWALGVL 228
              W  G L
Sbjct: 1168 PXWTCGAL 1145
>38560
          Length = 479

 Score = 60.5 bits (145), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 37/130 (28%), Positives = 58/130 (44%), Gaps = 6/130 (4%)
 Frame = -3

Query: 198 TLCGTPEYLAPEIILSKGY-NKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKV 256
           T CG+P Y APE+I    Y     D W++GVL+Y +  GY PF  ++   + +K    K 
Sbjct: 408 TCCGSPAYAAPELISGLEYLGSEADIWSMGVLLYALLCGYLPFDDEKXSHL*QKNQKRKD 229

Query: 257 RFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWF-----ATTDWIAIYQRKV 311
             P   S D   LL  +LQ D + R       +  +  H W         +W + Y+R +
Sbjct: 228 EVPEWLSEDTTKLLEGMLQTDPSHRI-----TIRRLLDHHWLNQGFNVPVEWASKYKRTL 64

Query: 312 EAPFIPKFRG 321
           +   + +  G
Sbjct: 63  DEDCLTEAGG 34
>28157
          Length = 400

 Score = 60.1 bits (144), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 43/124 (34%), Positives = 66/124 (53%), Gaps = 13/124 (10%)
 Frame = +3

Query: 79  KVVKLKQIEHTLNEKRILQA------VEFPFLVRLEYSFKDNSNLYMVMEYVPGGEMFSH 132
           K V +K+IE    +K  +Q       V  P +V L  + +D+  + +VMEY  GG +++ 
Sbjct: 3   KDVAVKRIESEQEKKSFMQELKQLSRVSHPNIVCLYGACRDHP-VCLVMEYAEGGSLYNV 179

Query: 133 LRRIG---RFSEPHARFYAAQIVLTFEYLHSLD---LIYRDLKPENLLIDHQGY-IQVTD 185
           L   G   +++  HA  +  Q  L  EYLH +    LI+RDLKP NLL+   G  +++ D
Sbjct: 180 LHGSGPQPQYTAAHAMNWLLQCALGVEYLHGMKPKALIHRDLKPPNLLLIQCGTKLKICD 359

Query: 186 FGFA 189
           FG A
Sbjct: 360 FGTA 371
>21808
          Length = 1011

 Score = 58.9 bits (141), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 44/192 (22%), Positives = 85/192 (44%), Gaps = 11/192 (5%)
 Frame = +1

Query: 90  LNEKRILQAVEFPFLVRLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSE-PHARFYA 148
           L E +I++ +  P L++L      +  ++++ E +  G +   L+  GR  + P      
Sbjct: 76  LAEAQIMKKLRHPKLIQLYAVCTQDDPIFIITELMKNGSLLEFLQGKGRVLKLPALIDIG 255

Query: 149 AQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVK--------GRTWTLC 200
           AQI     YL S + I+RDL   N+L+     +++ DFG A+ +K        G  + + 
Sbjct: 256 AQIACGMAYLESQNYIHRDLAARNILVSDNNTVKIADFGLARVIKEDEYEARVGARFPI- 432

Query: 201 GTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAA-GYPPFFADQPIQIYEKIVSG-KVRF 258
              ++ APE      +    D W+ G+L+ E    G  P+      ++  ++  G ++  
Sbjct: 433 ---KWTAPEAANYNRFTIKSDVWSFGILLTETVTYGRVPYPGMTNAEVLHQVEHGYRMPC 603

Query: 259 PSHFSSDLKDLL 270
           P      L D++
Sbjct: 604 PPGCPKPLYDIM 639
>19301
          Length = 712

 Score = 57.8 bits (138), Expect = 6e-09,   Method: Compositional matrix adjust.
 Identities = 45/157 (28%), Positives = 71/157 (45%)
 Frame = +2

Query: 31  WENPPPSNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTL 90
           WE P  S   LE       LG+G+ G V L K  A E            V K++ I+ T 
Sbjct: 290 WEIPFESITDLE------WLGSGAQGAVFLGKLCAEEV----------AVKKVRDIKET- 418

Query: 91  NEKRILQAVEFPFLVRLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQ 150
            + R L+ +  P ++  +          ++MEY P G+++  LR            ++ Q
Sbjct: 419 -DIRNLRKLNHPNIISFKGVCTQAPCYCIIMEYCPYGQLYEVLRDGKEIPPALVLDWSKQ 595

Query: 151 IVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFG 187
           I     YLHS  +I+RDLK  N+L+     ++++DFG
Sbjct: 596 IASGMNYLHSHKIIHRDLKSPNVLVAKNDVVKISDFG 706
>04852
          Length = 1462

 Score = 57.8 bits (138), Expect = 7e-09,   Method: Compositional matrix adjust.
 Identities = 41/144 (28%), Positives = 68/144 (47%), Gaps = 8/144 (5%)
 Frame = +1

Query: 124 VPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQV 183
            PGG +   +RR    S      YA QI    E+L S   I+RDL   N+L+  +  +++
Sbjct: 298 TPGGHV---IRRKNLLS------YAFQIARGMEFLASRKCIHRDLAARNVLVTEEHVLKI 450

Query: 184 TDFGFA-------KRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEM-AAG 235
            DFG +       KR  GR        +++APE +    Y    D W+ GV+++E+ + G
Sbjct: 451 ADFGLSRTGDYYKKRSGGRL-----PVKWMAPEALFDMRYTTKSDVWSFGVVLWEIFSLG 615

Query: 236 YPPFFADQPIQIYEKIVSGKVRFP 259
             P+ +    ++Y K++    R P
Sbjct: 616 GMPYASIPNEELYSKLLDDAYRMP 687
>04591
          Length = 1117

 Score = 57.4 bits (137), Expect = 8e-09,   Method: Compositional matrix adjust.
 Identities = 44/166 (26%), Positives = 80/166 (48%), Gaps = 17/166 (10%)
 Frame = -2

Query: 89   TLNEKRILQAVEFPFLVRLEYSFKDN--------SNLYMVMEYVP--GGEMFSHLRRIGR 138
             L E +ILQ +E   +V+L+              S  Y++ EY       + ++LR   +
Sbjct: 1080 ALREIKILQQLEHENVVQLQEICHTQAGPYNRYKSTFYLIFEYCDYDLAGLLNNLRV--K 907

Query: 139  FSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGF------AKRV 192
            FS    +   +Q++    Y+H+  +++RD+K  N+L+   G +++ DFG       +KR+
Sbjct: 906  FSLADKKNLMSQLLNGLFYIHTKQILHRDIKAANILLTRDGVLKLADFGLSRPWVKSKRL 727

Query: 193  KGRTWTLCGTPEYLAPEIILS-KGYNKAVDWWALGVLIYEMAAGYP 237
              R  TL     Y  PE++L  + Y   +D W +G ++ EM +  P
Sbjct: 726  TNRVVTLW----YRPPELLLGEREYGPEIDMWGVGCIMAEMWSRKP 601
>11780
          Length = 1713

 Score = 57.0 bits (136), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 42/151 (27%), Positives = 68/151 (45%), Gaps = 2/151 (1%)
 Frame = +3

Query: 42  EDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVEF 101
           +D E  + +G G FG V          Y    +  KQ   K +  +  L E  ++ ++  
Sbjct: 597 QDLEIGEAIGKGDFGDVY------KGMYRGQPVAIKQLKDKDRGEQSFLQEASVMTSLRH 758

Query: 102 PFLVRLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGR--FSEPHARFYAAQIVLTFEYLH 159
             LVRL         +++V E++  G +  +LR  GR   ++     +A       EYL 
Sbjct: 759 DNLVRL-IGVVLGETIFLVTEFMGKGNLVEYLRSRGRSVITKKDQINFATDTCAAMEYLE 935

Query: 160 SLDLIYRDLKPENLLIDHQGYIQVTDFGFAK 190
           S  L++RDL   N+L+   G  +V+DFG AK
Sbjct: 936 SKRLVHRDLAARNVLVHDDGKAKVSDFGLAK 1028
>32957
          Length = 645

 Score = 56.2 bits (134), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 24/41 (58%), Positives = 30/41 (73%)
 Frame = +3

Query: 194 GRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAA 234
           GRT T CGT EY+APE+   K Y K VDWW LG+L++E+ A
Sbjct: 30  GRTRTFCGTREYMAPEVHERKEYGKEVDWWGLGILLHELLA 152
>12786
          Length = 460

 Score = 54.3 bits (129), Expect = 7e-08,   Method: Compositional matrix adjust.
 Identities = 34/120 (28%), Positives = 58/120 (48%), Gaps = 25/120 (20%)
 Frame = -3

Query: 145 RFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRV-KGRTWTL---- 199
           +FY  +++   + LH+  +I+ DLKP N ++   G +++ DFG A  + + +T  L    
Sbjct: 401 KFYWREMLRAVKALHNEGVIHSDLKPANFML-VAGNLKLIDFGIANTLQQDKTSVLKDSR 225

Query: 200 CGTPEYLAPEIILSKGYNKA--------------------VDWWALGVLIYEMAAGYPPF 239
            GTP Y++PE I++   + A                     D W+LG ++Y M  G  PF
Sbjct: 224 VGTPSYMSPEAIMAACDDSADDSMEEDGHRTKPKYKVGVRSDVWSLGCILYNMVYGRTPF 45
>03508
          Length = 1463

 Score = 54.3 bits (129), Expect = 7e-08,   Method: Compositional matrix adjust.
 Identities = 31/113 (27%), Positives = 63/113 (55%), Gaps = 4/113 (3%)
 Frame = +1

Query: 139 FSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQG-YIQVTDFGFAKRVK-GRT 196
           F++   RFY  +++   ++ HS+ +++RD+KP N++IDH+   +++ D+G A+    G  
Sbjct: 862 FTDYDIRFYLYELMKALDFCHSMGIMHRDVKPHNVMIDHENKKLRLIDWGLAEFYHPGME 1041

Query: 197 WTLCGTPEYL-APEIILS-KGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQI 247
           + +     Y   PE++L  + Y+ ++D W+LG +   M     P    +P Q+
Sbjct: 1042YNVRVASRYFKGPELLLDYQMYDYSLDMWSLGCMFASMIFRKEPLLP-RPRQL 1197
>07940
          Length = 1336

 Score = 53.9 bits (128), Expect = 9e-08,   Method: Compositional matrix adjust.
 Identities = 29/91 (31%), Positives = 49/91 (53%), Gaps = 5/91 (5%)
 Frame = -3

Query: 147 YAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKG----RTWTLCGT 202
           YA Q+    EYL S   I+RDL   N+L+  +  +++ DFG  + ++     R  T    
Sbjct: 332 YAYQVARGMEYLASKQCIHRDLAARNVLVAEEYVLKIADFGLTRNLQQFDYYRKTTDGRL 153

Query: 203 P-EYLAPEIILSKGYNKAVDWWALGVLIYEM 232
           P +++APE +  + Y    D W+ GVL++E+
Sbjct: 152 PVKWMAPEALFDRKYTSKSDVWSYGVLLWEI 60
>04138
          Length = 800

 Score = 53.1 bits (126), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 29/88 (32%), Positives = 46/88 (52%), Gaps = 7/88 (7%)
 Frame = +1

Query: 157 YLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAK------RVKGRTWTLCGTPEYLAPEI 210
           Y+H   +++RD+K  N+LI  QG +++ DFG A+      R   R      T  Y  PE+
Sbjct: 58  YIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRVVTLWYRPPEL 237

Query: 211 ILS-KGYNKAVDWWALGVLIYEMAAGYP 237
           +L  + Y+ A+D W  G ++ EM    P
Sbjct: 238 LLGDRNYSTAIDQWGAGCIMAEMWTRNP 321
>16708
          Length = 1397

 Score = 51.6 bits (122), Expect = 4e-07,   Method: Compositional matrix adjust.
 Identities = 41/160 (25%), Positives = 70/160 (43%), Gaps = 14/160 (8%)
 Frame = -1

Query: 48   KTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQ---IEHTLNEKRILQAVEFPFL 104
            + LG G FG+V           Y  ++L   +   LK      H+L+E   L  +E  F 
Sbjct: 1385 QVLGKGVFGKV-----------YEARLLSTHEKAALKTSILCHHSLDEVEALGRIEGGFY 1239

Query: 105  VRLEYS-------FKDNSNLYMVMEYVPGGEMFSHLRRIG---RFSEPH-ARFYAAQIVL 153
            +   +        F   + L    E  P   +++H +      R+S P      A Q V 
Sbjct: 1238 LAQMFGAWVTCLPFPKMNILLHFYEMGPLCNVYAHYKNKEMPIRWSNPAMVCCIAGQXVC 1059

Query: 154  TFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVK 193
              E++H L +++ D+K +N+L+D  G  ++TD+G A+  K
Sbjct: 1058 ALEHIHELGVVHMDVKADNVLVDAHGNCKLTDYGIAQLYK 939
>20152
          Length = 445

 Score = 51.6 bits (122), Expect = 5e-07,   Method: Compositional matrix adjust.
 Identities = 29/96 (30%), Positives = 44/96 (45%), Gaps = 1/96 (1%)
 Frame = +1

Query: 208 PEIILSKGYN-KAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDL 266
           PEI+L   Y+  AVD W+LGV++Y +  G  PF      +    I+  + + P H S   
Sbjct: 1   PEILLGDSYDAPAVDVWSLGVILYMLVVGEAPFQEANDSETLTMIMDCRYQIPPHISHKC 180

Query: 267 KDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTD 302
           +DL+  +LQ +   R       +  I  H W    D
Sbjct: 181 QDLIEKMLQREPVDR-----ASLPHILAHPWLNDGD 273
>37602
          Length = 804

 Score = 48.5 bits (114), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 23/77 (29%), Positives = 38/77 (49%)
 Frame = -1

Query: 110 SFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLK 169
           S+     L++ MEY  GG M       G  +EP   F   + +    YLH    ++RD+K
Sbjct: 315 SYLRREKLWIAMEYCGGGSMQDIYHVTGPLTEPQIAFVCRETLKGLHYLHRRGKMHRDIK 136

Query: 170 PENLLIDHQGYIQVTDF 186
             N+L+  +G +++ DF
Sbjct: 135 GANILLTEEGDVKLADF 85
>00715
          Length = 1788

 Score = 48.5 bits (114), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 44/178 (24%), Positives = 79/178 (44%), Gaps = 29/178 (16%)
 Frame = +1

Query: 109 YSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARF-YAAQIVLTFEYLHSLDLIYRD 167
           + F+D +  ++ MEYV    + + L    +  +   R   A Q+     YLHS+++++ D
Sbjct: 142 HRFEDGA--WLAMEYVGPLNLQTILNDHQQDIDSSMRLSLALQMARGLHYLHSINIVHLD 315

Query: 168 LKPENLLIDHQGYIQVTDFGFAKR------------------------VKGRTWT--LCG 201
           LKP N L+     +++ DFG   +                        V+G  W   L G
Sbjct: 316 LKPANCLLTRDLKLRIADFGCCHQLTPTGLDMGEREGGMAGNELELTPVQG-AWKNELAG 492

Query: 202 TPEYLAPEIILSKGYNKAV--DWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVR 257
           T  Y APE++  KG   +V  D ++LG+ +++M     P+       +  ++VS  +R
Sbjct: 493 TLAYRAPELL--KGLQPSVRSDVYSLGITLWQMCTRQGPYEGVPAHAVVYQVVSKDLR 660
>14116
          Length = 1017

 Score = 46.6 bits (109), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 27/123 (21%), Positives = 60/123 (48%), Gaps = 9/123 (7%)
 Frame = -1

Query: 119 MVMEYVPGGEMFSHLRRIGRFSEPHAR---FYAAQIVLTFEYLHSLDLIYRDLKPENLLI 175
           +V+ ++  G++ +++R      +P  +    Y   I    +YL  L  ++RDL   N ++
Sbjct: 393 VVLPFMKHGDLLTYIRDDQH--QPTIKDLIMYGVDIARGMDYLAGLKFVHRDLAARNCML 220

Query: 176 DHQGYIQVTDFGFAKRVKGRTWTLCGTP------EYLAPEIILSKGYNKAVDWWALGVLI 229
           D   +++V DFG A+ +  + +            +++A E +    Y+   D W+ GV++
Sbjct: 219 DEDFHVKVADFGLARDIYEKEYYSSENKKAKLPVKWMALESLEKGNYDSKTDVWSYGVVL 40

Query: 230 YEM 232
           +E+
Sbjct: 39  WEL 31
>27274
          Length = 396

 Score = 46.2 bits (108), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 28/102 (27%), Positives = 49/102 (48%), Gaps = 11/102 (10%)
 Frame = -1

Query: 209 EIILSKGYNKAVDWWALGVLIYEMAAGYPPF--------FADQPIQIYEKIVSGKVRFPS 260
           E++  + +   VD W+LG+L++E+ +G+ PF         A   + +Y +I+ G  R   
Sbjct: 375 ELLRGQQHGPTVDMWSLGILLHELLSGHVPFEPERGSRQMARNMMAVYAQIIRGSSRDVC 196

Query: 261 H---FSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFA 299
                S+   D LR L+Q++ TKR  +         +H W A
Sbjct: 195 DGLALSTHGADFLRRLVQLEDTKRLTS-----QQAFSHPWIA 85
>07291
          Length = 833

 Score = 45.4 bits (106), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 25/100 (25%), Positives = 53/100 (53%), Gaps = 7/100 (7%)
 Frame = +1

Query: 147 YAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTW-TLCGTP-- 203
           +  QI     YL  + +++R+L   N ++   G +Q++D+G    +  +++ T   +P  
Sbjct: 64  FGRQIADGMAYLQEVKVVHRNLAARNCIVTEDGRLQLSDYGVTGSLFPQSYYTADDSPAR 243

Query: 204 ---EYLAPEIILSKGYNKAVDWWALGVLIYEMAA-GYPPF 239
              +++APE I +  ++   D WA GV+++E+   G  P+
Sbjct: 244 DLVKWMAPETIDNFHFSSKSDVWAFGVVLWELLTRGITPY 363
>33586
          Length = 551

 Score = 45.4 bits (106), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 17/49 (34%), Positives = 33/49 (67%)
 Frame = +2

Query: 103 FLVRLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQI 151
           F+V L Y+F+    LY+++E++ GG++F+ L +   F+E   +FY A++
Sbjct: 404 FIVHLHYAFQTEGKLYLILEFLRGGDLFTRLSKEVMFTEEDVKFYLAEL 550
>02638
          Length = 1490

 Score = 45.1 bits (105), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 27/105 (25%), Positives = 49/105 (46%), Gaps = 5/105 (4%)
 Frame = +1

Query: 199 LCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFA---DQPIQIYEKIVSG- 254
           L GT  ++APE++  + Y +A D W++G ++ EM    PP+ +      + +  KI S  
Sbjct: 16  LLGTIAFMAPEVLRGESYGRACDVWSVGCVMIEMCTCRPPWNSHDISNHLALIFKIASSV 195

Query: 255 -KVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWF 298
                P + S  ++DL+   L+ D      + +    D+  H  F
Sbjct: 196 DPPPIPENMSPPVRDLMLRCLEQD-----SDFRPSAKDLLMHPLF 315
>17300
          Length = 480

 Score = 45.1 bits (105), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 32/112 (28%), Positives = 55/112 (49%), Gaps = 8/112 (7%)
 Frame = +1

Query: 158 LHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRT----WTLCGTP---EYLAPEI 210
           L  +  ++RDL   N+L++     +V DFG ++ ++  T    +T  G      + APE 
Sbjct: 22  LADMGYVHRDLAARNILVNEILVCKVADFGLSREIESDTTEGAYTTKGGKIPVRWTAPEA 201

Query: 211 ILSKGYNKAVDWWALGVLIYE-MAAGYPPFFADQPIQIYEKIVSGKVRFPSH 261
           I  + +  A D W+ GV+++E M+ G  P++ +   Q   K V    R P H
Sbjct: 202 IAYRKFTSASDVWSFGVVMWEVMSYGERPYW-NWSNQDVIKAVEKGYRLPLH 354
>17932
          Length = 597

 Score = 43.9 bits (102), Expect = 9e-05,   Method: Compositional matrix adjust.
 Identities = 29/91 (31%), Positives = 43/91 (47%)
 Frame = -3

Query: 243 QPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTD 302
           QPI I   I   +V   S  S + +DL+  LL        G  + G  +++ H +F T D
Sbjct: 517 QPITIS*TIRQTQVPPHSSVSKEARDLISQLLSD------GKSRLGWPELQQHPFFKTVD 356

Query: 303 WIAIYQRKVEAPFIPKFRGSGDTSNFDDYEE 333
           W  I  R    P++P      DTS+FD+ E+
Sbjct: 355 WANI--RNAMPPYVPSISSLDDTSHFDEVEK 269

 Score = 32.3 bits (72), Expect = 0.26,   Method: Compositional matrix adjust.
 Identities = 16/41 (39%), Positives = 20/41 (48%), Gaps = 2/41 (4%)
 Frame = -2

Query: 222 WWALGVLIYEMAAGYPPFFADQP--IQIYEKIVSGKVRFPS 260
           WW+LGV  YEM  G  PF  D    +  Y  I++ K    S
Sbjct: 596 WWSLGVCAYEMLFGCTPFTDDDGSMVATYNNIMNYKTNSSS 474
>18401
          Length = 463

 Score = 42.4 bits (98), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 16/42 (38%), Positives = 26/42 (61%)
 Frame = -3

Query: 198 TLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPF 239
           T+  T  Y APE+IL  G++   D W++G +++E+  GY  F
Sbjct: 455 TIVSTRHYRAPEVILELGWSHPCDVWSVGCIMFELYTGYTLF 330
>14477
          Length = 493

 Score = 42.0 bits (97), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 34/145 (23%), Positives = 67/145 (46%), Gaps = 2/145 (1%)
 Frame = -1

Query: 50  LGTGSFGRVM--LVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVEFPFLVRL 107
           LG G+FG VM  + +    E   A+K+L    +    Q E  + E  +++ ++   +VRL
Sbjct: 466 LGAGNFGSVMKGVCRLDDREIPVAIKVLKNADLDPSVQSE-LIKEAEVMKKMDHMHIVRL 290

Query: 108 EYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRD 167
                +   + +V+E    G +   L +       +      Q+    EYL +   ++RD
Sbjct: 289 -IGLCEGETMMLVLELAKLGPLNKFLPKNKHLPLWNILELMWQVSQGMEYLEANKFVHRD 113

Query: 168 LKPENLLIDHQGYIQVTDFGFAKRV 192
           L   N+L+  + + +++DFG +K +
Sbjct: 112 LAARNILLCDEHFAKISDFGMSKTL 38
>12672
          Length = 773

 Score = 40.8 bits (94), Expect = 8e-04,   Method: Compositional matrix adjust.
 Identities = 28/89 (31%), Positives = 46/89 (51%), Gaps = 8/89 (8%)
 Frame = +3

Query: 155 FEYLHSLDLIYRDLKPENLLIDHQGYIQVTDF--------GFAKRVKGRTWTLCGTPEYL 206
            +YL+    ++RD+K  N+L+D +   +V DF        G  K V+  +  + GT  YL
Sbjct: 30  IQYLNDNGHVHRDIKTANILLDSEYTAKVGDFATVVSAPSGEGKTVQNAS-VVIGTAAYL 206

Query: 207 APEIILSKGYNKAVDWWALGVLIYEMAAG 235
           APE I      K +D ++ GV++ E+  G
Sbjct: 207 APEAIHFDVSTK-LDSYSFGVVLLEVITG 290
>20640
          Length = 1492

 Score = 40.8 bits (94), Expect = 8e-04,   Method: Compositional matrix adjust.
 Identities = 26/86 (30%), Positives = 43/86 (50%), Gaps = 5/86 (5%)
 Frame = +1

Query: 164 IYRDLKPENLLIDHQGYIQVTDFGFAKRVKG----RTWTLCGTP-EYLAPEIILSKGYNK 218
           ++RDL   N L+ H   ++++DFG A+ V      R       P  ++  E IL   ++ 
Sbjct: 10  VHRDLATRNCLVGHDLVVKISDFGLARSVHSVDYYRGSEHDAIPIRWMPLEAILYNKFST 189

Query: 219 AVDWWALGVLIYEMAAGYPPFFADQP 244
             D W+ GV+++E+ A     FA QP
Sbjct: 190 QSDVWSFGVVLWEIFA-----FALQP 252
>31489
          Length = 329

 Score = 40.8 bits (94), Expect = 8e-04,   Method: Compositional matrix adjust.
 Identities = 25/70 (35%), Positives = 39/70 (55%), Gaps = 4/70 (5%)
 Frame = +3

Query: 109 YSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEP----HARFYAAQIVLTFEYLHSLDLI 164
           + FKD   ++ +ME        S L RI    +P    H R++  QI+   +Y+HS +++
Sbjct: 78  HDFKDIHVVFDLME--------SDLHRIIYSDQPLTEEHIRYFLYQILRGLKYIHSANVV 233

Query: 165 YRDLKPENLL 174
           +RDLKP NLL
Sbjct: 234 HRDLKPSNLL 263
>29590
          Length = 320

 Score = 40.4 bits (93), Expect = 0.001,   Method: Composition-based stats.
 Identities = 17/41 (41%), Positives = 25/41 (60%)
 Frame = +3

Query: 199 LCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPF 239
           + GTP+Y+APE++  +  +   D W+LGVL Y M     PF
Sbjct: 54  IIGTPDYVAPEVLDYEPLSIQTDMWSLGVLSYVMLTACSPF 176
>11404
          Length = 563

 Score = 40.0 bits (92), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 40/147 (27%), Positives = 69/147 (46%), Gaps = 6/147 (4%)
 Frame = +1

Query: 35  PPSNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKIL-DKQKVVKLKQIEHTLNEK 93
            P     + +E    +G GSFG+V+        +  A+KI+ +K+  +   QIE  L E 
Sbjct: 118 SPGEKWADRYEIDSLIGKGSFGQVVKAYDHTDNEQVAIKIIKNKKPFLNQAQIEVKLLEM 297

Query: 94  RILQAVEFPF-LVRLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIG--RFSEPHARFYAAQ 150
                 +  + +VRL+  F   S+L +V E +    ++  LR       S    R +A Q
Sbjct: 298 MNRHDTDNKYYIVRLKRHFMFRSHLCLVFELLSYN-LYDLLRNTNFRGVSLNLTRKFAQQ 474

Query: 151 IVLTFEYLHS--LDLIYRDLKPENLLI 175
           +     +L +  + +I+ DLKPEN+L+
Sbjct: 475 LCTALLFLATPEMSIIHCDLKPENILL 555
>26009
          Length = 886

 Score = 39.7 bits (91), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 23/72 (31%), Positives = 35/72 (48%), Gaps = 3/72 (4%)
 Frame = +3

Query: 127 GEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQV--- 183
           G   +  RR        A+    Q+V   +++HS  L++RD+KPEN+LI    + +V   
Sbjct: 666 GTCLTPSRRNKACGSREAKSVMKQLVSALDFMHSKQLVHRDIKPENVLILTPDFSRVS*W 845

Query: 184 TDFGFAKRVKGR 195
           T    A RV  R
Sbjct: 846 TSA*LANRVHRR 881
>37063
          Length = 455

 Score = 39.3 bits (90), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 24/78 (30%), Positives = 39/78 (50%), Gaps = 16/78 (20%)
 Frame = -2

Query: 168 LKPENLLIDHQGYI---QVTDFGFAKRVKG--------RTWTLCGTPEYLAPEII----- 211
           LKPEN+L +H   +   ++ DF  A  +             T  G+ EY+APE++     
Sbjct: 454 LKPENILCEHLDEVVPLKICDFDLASGINCDGDGTKTPELLTPVGSAEYMAPEVVDAWVG 275

Query: 212 LSKGYNKAVDWWALGVLI 229
            S  Y+K  D W+LG+++
Sbjct: 274 ESFSYDKRCDMWSLGIIL 221
>18481
          Length = 437

 Score = 39.3 bits (90), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 24/75 (32%), Positives = 39/75 (52%), Gaps = 3/75 (4%)
 Frame = -1

Query: 128 EMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLID---HQGYIQVT 184
           E+F   +R  RF+       + Q++   E++H    I+RDLKP+N L+    H   + + 
Sbjct: 233 ELFVICKR--RFTLKTILMVSDQLLSRLEFIHQKCFIHRDLKPDNFLMGLGRHCHRLYII 60

Query: 185 DFGFAKRVKGRTWTL 199
           DFG +KR K    T+
Sbjct: 59  DFGLSKRYKDTQGTM 15
>17516
          Length = 453

 Score = 38.1 bits (87), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 17/39 (43%), Positives = 28/39 (71%), Gaps = 1/39 (2%)
 Frame = -3

Query: 198 TLCGTPEYLAPEIILSKG-YNKAVDWWALGVLIYEMAAG 235
           TL GTP Y+APE++L KG Y+   D ++L ++++E+  G
Sbjct: 442 TLAGTPVYMAPEVLLQKGQYDMKADVYSLAIILWELWYG 326
>17637
          Length = 447

 Score = 37.0 bits (84), Expect = 0.011,   Method: Compositional matrix adjust.
 Identities = 24/89 (26%), Positives = 42/89 (47%), Gaps = 6/89 (6%)
 Frame = +1

Query: 172 NLLIDHQGYIQVTDFGFAKRVKGRTWTLCGTPEY-----LAPEIILSKGYNKAVDWWALG 226
           N +ID Q  +++TD   ++ +    +   G  EY     L+ E +    YN+  D W+ G
Sbjct: 1   NCVIDDQLRVKLTDSALSRDLFSGDYNCLGDGEYRPIKWLSLEALQKSHYNEGSDVWSFG 180

Query: 227 VLIYEMAA-GYPPFFADQPIQIYEKIVSG 254
           VL++EM   G  P+    P ++   +  G
Sbjct: 181 VLMWEMCTLGKLPYAEIDPYEMEHYLKDG 267
>18996
          Length = 491

 Score = 37.0 bits (84), Expect = 0.011,   Method: Compositional matrix adjust.
 Identities = 21/74 (28%), Positives = 41/74 (55%), Gaps = 5/74 (6%)
 Frame = +2

Query: 164 IYRDLKPENLLIDHQGYIQVTDFGFAK--RVKGRTWTLCGTP---EYLAPEIILSKGYNK 218
           I+RDL   N+L+D +  ++++DFG A+     G  + +       ++ +PE I +  ++ 
Sbjct: 2   IHRDLAARNILVD-RSCVKISDFGLAQFANADGYYYGISQRDIPIKWYSPEAIETCKFSS 178

Query: 219 AVDWWALGVLIYEM 232
             D W+ GV ++EM
Sbjct: 179 YSDVWSYGVTLFEM 220
>17253
          Length = 483

 Score = 36.2 bits (82), Expect = 0.023,   Method: Compositional matrix adjust.
 Identities = 20/86 (23%), Positives = 43/86 (50%), Gaps = 12/86 (13%)
 Frame = -1

Query: 119 MVMEYVPGGEMFSHLRR---------IGRFSEPHAR---FYAAQIVLTFEYLHSLDLIYR 166
           ++ME+   G++ S LR+             ++  AR    +A  +     ++ +  +++R
Sbjct: 315 ILMEFCCHGDLLSFLRKRRPDRTVFLTSTANDLTARDFFSFALHVARGMAHVANNKIVHR 136

Query: 167 DLKPENLLIDHQGYIQVTDFGFAKRV 192
           D+   N+LI  +   +V+DFG ++RV
Sbjct: 135 DVAARNVLISERNVCKVSDFGLSRRV 58
>06358
          Length = 1517

 Score = 35.4 bits (80), Expect = 0.031,   Method: Compositional matrix adjust.
 Identities = 32/154 (20%), Positives = 67/154 (43%), Gaps = 22/154 (14%)
 Frame = +3

Query: 150 QIVLTFEYLHS-LDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTWTLCGTP----- 203
           Q+     +LH+   +++R++ PE +++   G  ++  + F  R      T    P     
Sbjct: 384 QVTEALGFLHNDAKMMHRNVCPEAIMLTKLGSWKLAGYEFCVRSSDPQSTDPSYPFYEWR 563

Query: 204 -----------EYLAPEIILSKGYNKAVDWWALGVLIYEM-AAGYPPFFADQPIQIY--- 248
                      +++APE +L+       D ++LG+L+Y + A G P F  +  +  +   
Sbjct: 564 SDIAPVTQPHLDFMAPEYVLTMQCGTGSDMFSLGLLVYSVFAKGKPLFECNGELSAFKSN 743

Query: 249 -EKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKR 281
            E++   +V        DL+D ++ LL ++   R
Sbjct: 744 AEELRHMRVSLLGVVPEDLRDHVKLLLNIEPAVR 845
>25360
          Length = 751

 Score = 35.4 bits (80), Expect = 0.036,   Method: Compositional matrix adjust.
 Identities = 21/54 (38%), Positives = 28/54 (51%), Gaps = 5/54 (9%)
 Frame = -3

Query: 166 RDLKPENLLIDHQGYI-QVTDFGFAKRVKGRTWT--LCGTPEYL--APEIILSK 214
           R L P  L    QG   +V D G+A  V G+TWT  +CGTP +    P  + S+
Sbjct: 422 RSLTPGGLEALFQGQCPRVQDLGWASHVNGKTWTHYVCGTPHWQHDCPRRVRSR 261
>11089
          Length = 1213

 Score = 35.0 bits (79), Expect = 0.041,   Method: Compositional matrix adjust.
 Identities = 21/54 (38%), Positives = 28/54 (51%), Gaps = 5/54 (9%)
 Frame = +2

Query: 166  RDLKPENLLIDHQGYI-QVTDFGFAKRVKGRTWT--LCGTPEYL--APEIILSK 214
            R L P  L    QG   +V D G+A  V G+TWT  +CGTP +    P  + S+
Sbjct: 974  RSLTPGGLEALFQGQCPRVQDLGWASHVNGKTWTHYVCGTPHWQHDCPRRVRSR 1135
>21210
          Length = 518

 Score = 34.3 bits (77), Expect = 0.070,   Method: Compositional matrix adjust.
 Identities = 27/91 (29%), Positives = 43/91 (47%), Gaps = 10/91 (10%)
 Frame = +3

Query: 201 GTPEYLAPEII----LSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIY---EKIVS 253
           G   Y+APE I     S GY+   D W+LG+ + E+A G  P+   + + I+   +++V 
Sbjct: 6   GCRPYMAPERIDPRASSHGYDVRSDVWSLGITLMELATGRFPY--RKWVSIFDQLQQVVR 179

Query: 254 GKVRFPSH---FSSDLKDLLRNLLQVDLTKR 281
           G      H   FS D  + +   L  D  +R
Sbjct: 180 GVAPCLPHDGAFSHDFVNFVNKCLTKDEKQR 272
>17591
          Length = 474

 Score = 32.7 bits (73), Expect = 0.20,   Method: Compositional matrix adjust.
 Identities = 14/46 (30%), Positives = 28/46 (60%)
 Frame = +2

Query: 230 YEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQ 275
           +EM  G PPF++    ++YE I+   +R  ++ S+  +++L  LL+
Sbjct: 2   FEMLYGLPPFYSRDTSEMYENILYKPLRLRTNVSAAGRNILEELLK 139
>01106
          Length = 878

 Score = 32.7 bits (73), Expect = 0.23,   Method: Compositional matrix adjust.
 Identities = 37/145 (25%), Positives = 63/145 (43%), Gaps = 17/145 (11%)
 Frame = +3

Query: 48  KTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQ--IEHTLNEKRILQAVE----- 100
           + LG G F  V L      +++ A+K      VVK  Q   E  L+E ++L+ V      
Sbjct: 336 RKLGWGHFSTVWLCWDLTCKRFVALK------VVKSAQHYTETALDEVKLLKCVRESDVA 497

Query: 101 -------FPFLVRLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEP--HARFYAAQI 151
                     L   + S  + +++ MV E V G  +   + R      P  + +    Q+
Sbjct: 498 DPARAKCVQLLDDFKISGVNGTHVAMVFE-VLGYNLLKLIIRSNYQGIPIHNVKLIIRQV 674

Query: 152 VLTFEYLHS-LDLIYRDLKPENLLI 175
           +    Y+H+   +I+ D+KPEN+LI
Sbjct: 675 LEGLSYMHAKCRIIHTDIKPENILI 749
>21800
          Length = 855

 Score = 32.7 bits (73), Expect = 0.23,   Method: Compositional matrix adjust.
 Identities = 35/148 (23%), Positives = 60/148 (40%), Gaps = 3/148 (2%)
 Frame = +2

Query: 31  WENPPPSNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTL 90
           W  P    AGL        L       V   +   + Q+Y    LD+ K++K  +     
Sbjct: 305 WTVPCRQKAGLGSLLHCLALLGSQL*AVCRFEGCESAQHYTETALDEIKLLKCVRNSDET 484

Query: 91  NEKRILQAVEFPFLVRLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEP--HARFYA 148
           +  R         L   + S  + +++ MV E V G  +   + R      P  + +   
Sbjct: 485 DPAR---EKSVQLLDDFKISGVNGTHVCMVFE-VLGYNLLKLIIRSNYQGIPVHNVKLII 652

Query: 149 AQIVLTFEYLHS-LDLIYRDLKPENLLI 175
            Q++    YLH+  ++I+ D+KPEN+LI
Sbjct: 653 RQVLEGLNYLHAKCNIIHTDIKPENILI 736
>26052
          Length = 562

 Score = 31.6 bits (70), Expect = 0.50,   Method: Compositional matrix adjust.
 Identities = 14/26 (53%), Positives = 19/26 (73%)
 Frame = -1

Query: 48  KTLGTGSFGRVMLVKHKATEQYYAMK 73
           K LG GSFG+VM ++HK T +  A+K
Sbjct: 373 KLLGVGSFGKVMALQHKDTGETLAVK 296
>00638
          Length = 1595

 Score = 30.8 bits (68), Expect = 0.92,   Method: Compositional matrix adjust.
 Identities = 11/38 (28%), Positives = 25/38 (65%)
 Frame = +2

Query: 139 FSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLID 176
           F++   RFY  +++   ++ HS+ +++RD+KP   L++
Sbjct: 407 FTDYDIRFYLYELMKALDFCHSMGIMHRDVKPSPPLVN 520
>36481
          Length = 806

 Score = 30.8 bits (68), Expect = 0.97,   Method: Compositional matrix adjust.
 Identities = 32/132 (24%), Positives = 57/132 (43%), Gaps = 4/132 (3%)
 Frame = +2

Query: 51  GTGSFGRVMLVKHKATEQYYAMKIL-DKQKVVKLKQIEHTLNEKRILQAVEFPFLVRLEY 109
           G G+FG+V+  K        A+KI+ +  K  +  ++E  + EK   +      +     
Sbjct: 389 GEGTFGKVVQCKDLLKGDDIALKIIKNVDKYREAAKLEINVLEKLREKDPHAKHMCVQML 568

Query: 110 SFKDNSNLYMVMEYVPGGEMFSHLR--RIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRD 167
            + D      +  ++ G  +F  L+    G +     R  + Q+     +LH   L + D
Sbjct: 569 DWFDYHGHVCISFHMLGLSVFDFLKDNSYGAYPIEQVRHISYQLCYAVNFLHENQLTHTD 748

Query: 168 LKPENLL-IDHQ 178
           LKPEN+L +D Q
Sbjct: 749 LKPENILFVDSQ 784
>16350
          Length = 1108

 Score = 30.0 bits (66), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 10/34 (29%), Positives = 18/34 (52%)
 Frame = +2

Query: 202 TPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAG 235
           T +Y   E+++  GY    D W+   + +E+A G
Sbjct: 419 TRQYRCLEVLIGAGYGTPADIWSTACMAFELATG 520
>36002
          Length = 253

 Score = 29.6 bits (65), Expect = 2.1,   Method: Composition-based stats.
 Identities = 18/55 (32%), Positives = 27/55 (49%), Gaps = 4/55 (7%)
 Frame = +1

Query: 247 IYEKIVSGKVRFPSH----FSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKW 297
           ++ +I  G   FPS      SS  KDL+R+LL  +  KR+       +D+  H W
Sbjct: 58  LFNRIQDGNYFFPSMEWSAISSSAKDLIRHLLVREPRKRY-----SAADVLKHPW 207
>30339
          Length = 384

 Score = 29.3 bits (64), Expect = 2.3,   Method: Compositional matrix adjust.
 Identities = 14/25 (56%), Positives = 16/25 (64%)
 Frame = -2

Query: 41 LEDFERKKTLGTGSFGRVMLVKHKA 65
          L DF   K LG GSFG+VML + K 
Sbjct: 77 LHDFNFIKVLGKGSFGKVMLAERKG 3
>06167
          Length = 1470

 Score = 28.9 bits (63), Expect = 2.9,   Method: Compositional matrix adjust.
 Identities = 12/42 (28%), Positives = 22/42 (52%)
 Frame = -2

Query: 183 VTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWA 224
           + D  FA R       +CG+   + P ++L+   NK+V +W+
Sbjct: 128 IIDESFACRFCM*YCVVCGSKYLILPSVLLNLNINKSVSFWS 3
>23319
          Length = 2235

 Score = 28.5 bits (62), Expect = 4.4,   Method: Compositional matrix adjust.
 Identities = 10/33 (30%), Positives = 19/33 (57%)
 Frame = +3

Query: 208 PEIILSKGYNKAVDWWALGVLIYEMAAGYPPFF 240
           P++  +K Y+ ++D W+ G +  E+A    P F
Sbjct: 3   PDVYXAKMYSTSIDMWSAGCIFAELANAGRPLF 101
>29360
          Length = 363

 Score = 28.1 bits (61), Expect = 5.1,   Method: Compositional matrix adjust.
 Identities = 28/116 (24%), Positives = 55/116 (47%), Gaps = 4/116 (3%)
 Frame = +3

Query: 64  KATEQYYAMKILDKQ-KVVKLKQIEHTLNEKRILQAVEFPFLVRLEYSFKDNSNLYMVME 122
           K T +  A+KIL       +  QIE ++ ++   ++ +    VR    F+  ++  +V E
Sbjct: 18  KGTSEIVAIKILKNHPSYARQGQIEVSILQRLSQESADDYNFVRAFECFQHKNHTCLVFE 197

Query: 123 YVPGGEMFSHLRRIGRFSE---PHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLI 175
            +    ++  L++  +F      + R    Q++     L  L LI+ DLKPEN+++
Sbjct: 198 MLEQN-LYDFLKQ-NKFQPLPLKYIRPITQQVLTALRKLKQLGLIHADLKPENIML 359
>24241
          Length = 413

 Score = 27.7 bits (60), Expect = 7.1,   Method: Compositional matrix adjust.
 Identities = 21/94 (22%), Positives = 41/94 (43%), Gaps = 12/94 (12%)
 Frame = -2

Query: 44  FERKKTLGTGSFGRVMLVKHKATEQYYAMKILDK------------QKVVKLKQIEHTLN 91
            +R   +G G++G V   +H+AT +  AMK +              +++  L+++ HT  
Sbjct: 337 LDRLSKIGEGTYGVVYKCRHRATGRKLAMKKIRLRGSEDGVPSSAIREIAMLRELRHT-- 164

Query: 92  EKRILQAVEFPFLVRLEYSFKDNSNLYMVMEYVP 125
                       LV LE    ++  L++V E++ 
Sbjct: 163 ----------QXLVCLEDVIMEDERLFLVFEFLS 92
>31120
          Length = 439

 Score = 27.7 bits (60), Expect = 8.2,   Method: Compositional matrix adjust.
 Identities = 22/95 (23%), Positives = 42/95 (44%), Gaps = 1/95 (1%)
 Frame = +1

Query: 209 EIILSKGYN-KAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLK 267
           E++    Y+ K  D W+LGV+++ M  G  PF      ++ E   S K  F       + 
Sbjct: 1   EVVCGVPYDPKMADAWSLGVILFIMLNGKMPFDDSNLNKLLEDQRSKKYSFRRKLQDLVS 180

Query: 268 DLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTD 302
              R+ + V L +    ++  ++++   +W  T D
Sbjct: 181 PNARSTVSV-LLEPNSAMRWDLNEVLNCQWLQTID 282
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|9910228|ref|NP_064393.1| FK506 binding protein
12-rapamycin associated protein 1 [Mus musculus]
         (2549 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

28814                                                                 219   1e-56
26068                                                                 110   9e-24
18312                                                                  64   9e-10
06655                                                                  51   7e-06
19343                                                                  40   0.008
34349                                                                  40   0.012
18761                                                                  39   0.019
05687                                                                  37   0.071
05045                                                                  31   6.3  
>28814
          Length = 372

 Score =  219 bits (559), Expect = 1e-56,   Method: Compositional matrix adjust.
 Identities = 101/123 (82%), Positives = 113/123 (91%)
 Frame = -3

Query: 2163 ITSKQRPRKLTLMGSNGHEFVFLLKGHEDLRQDERVMQLFGLVNTLLANDPTSLRKNLSI 2222
            ITSKQRPRKL++ GS+G E+ FLLKGHEDLRQDERVMQLFGLVN+LL N+  + R+NL+I
Sbjct: 370  ITSKQRPRKLSIFGSDGKEYQFLLKGHEDLRQDERVMQLFGLVNSLLRNNADTFRRNLTI 191

Query: 2223 QRYAVIPLSTNSGLIGWVPHCDTLHALIRDYREKKKILLNIEHRIMLRMAPDYDHLTLMQ 2282
             R+A IPLSTNSGLIGWVPHCDTLH LIRDYRE+KKILLNIEHR+MLRMAPDYDHLTLMQ
Sbjct: 190  TRFAAIPLSTNSGLIGWVPHCDTLHTLIRDYRERKKILLNIEHRLMLRMAPDYDHLTLMQ 11

Query: 2283 KVE 2285
            KVE
Sbjct: 10   KVE 2
>26068
          Length = 460

 Score =  110 bits (274), Expect = 9e-24,   Method: Composition-based stats.
 Identities = 49/129 (37%), Positives = 87/129 (67%)
 Frame = +2

Query: 2329 MVGYILGLGDRHPSNLMLDRLSGKILHIDFGDCFEVAMTREKFPEKIPFRLTRMLTNAME 2388
            M+GYI+GLGDRH  N+++D  +G+++HID+  CFE      + PE++PFR+T+ +  A+ 
Sbjct: 2    MIGYIIGLGDRHLDNVLVDLATGEVVHIDYNVCFEKGKNL-RVPERVPFRMTQNIETALG 178

Query: 2389 VTGLDGNYRTTCHTVMEVLREHKDSVMAVLEAFVYDPLLNWRLMDTNTKGNKRSRTRTDS 2448
            VTG++G +R +   V++ +R+ +++++ +LEAFVYDPL++W      T GN+     T +
Sbjct: 179  VTGVEGIFRLSSEHVLKTMRKGRETLLTLLEAFVYDPLVDW------TTGNEGG--YTGA 334

Query: 2449 YSAGQSVEI 2457
            +  G+ V +
Sbjct: 335  FYGGEMVSV 361
>18312
          Length = 560

 Score = 63.5 bits (153), Expect = 9e-10,   Method: Compositional matrix adjust.
 Identities = 28/59 (47%), Positives = 41/59 (69%)
 Frame = -3

Query: 2313 WFDRRTNYTRSLAVMSMVGYILGLGDRHPSNLMLDRLSGKILHIDFGDCFEVAMTREKF 2371
            WF  R  YTRS+A  S+VGYILGLGDRH  N+++D ++ +++HID G    +A+ +  F
Sbjct: 171  WFQCRLAYTRSVATNSIVGYILGLGDRHVMNILIDCVTAELIHIDLG----IALNKAIF 7

 Score = 56.2 bits (134), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 26/50 (52%), Positives = 35/50 (70%)
 Frame = -2

Query: 2191 DLRQDERVMQLFGLVNTLLANDPTSLRKNLSIQRYAVIPLSTNSGLIGWV 2240
            DLRQD  + Q+FGLVN LL++DP +  + L I+ Y V+PLS  SGL+ W 
Sbjct: 559  DLRQDAIMQQVFGLVNRLLSHDPATSTRQLHIRTYKVVPLSRCSGLLQWC 410
>06655
          Length = 1350

 Score = 50.8 bits (120), Expect = 7e-06,   Method: Composition-based stats.
 Identities = 34/116 (29%), Positives = 58/116 (50%), Gaps = 5/116 (4%)
 Frame = -2

Query: 2309 SSEVWFDRRTNYTRSLAVMSMVGYILGLGDRHPSNLMLDRLSGKILHIDFGDCFEVAMTR 2368
            +SE +   + N+ +S A   +V Y++ + DRH  N++LD   G I+HIDFG     +  +
Sbjct: 1292 NSEEFLTAQKNFVQSCAGYCLVCYLMQVKDRHNGNILLDA-EGHIIHIDFGFILSTSPGK 1116

Query: 2369 EKFPEKIPFRLTRMLTNAMEVTGLDGN-----YRTTCHTVMEVLREHKDSVMAVLE 2419
                E  PF+LT   T  +EV G  G+     ++          R+H D ++ ++E
Sbjct: 1115 NLGFENSPFKLT---TEFVEVMGGQGSDMFEYFKILMLQGFVASRKHMDQILPLVE 957
>19343
          Length = 430

 Score = 40.4 bits (93), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 36/141 (25%), Positives = 55/141 (39%), Gaps = 29/141 (20%)
 Frame = +3

Query: 2217 RKNLSIQRYAVIPLSTNSGLIGWVPHCDTLHALIRDYREKKKILLNIEHRIMLRMA---- 2272
            R     + Y+V PL   SGLI WV     L +L + +++++     ++  +         
Sbjct: 6    RMEYRARHYSVTPLGPRSGLIQWVEGATPLFSLYKKWQQREAYAQTLKPGVAASTTNTPA 185

Query: 2273 ----PD---YDHLTLMQK------------------VEVFEHAVNNTAGDDLAKLLWLKS 2307
                P    Y  LT   K                   +V E  +++T  D LAK LW  S
Sbjct: 186  TVPRPSEVYYSKLTPALKDKGIETSENRKEWPMSVLRKVLEDLMDDTPDDLLAKELWCAS 365

Query: 2308 PSSEVWFDRRTNYTRSLAVMS 2328
              +  W+     Y+RS AVMS
Sbjct: 366  GGAGEWWQMVQTYSRSTAVMS 428
>34349
          Length = 413

 Score = 40.0 bits (92), Expect = 0.012,   Method: Composition-based stats.
 Identities = 29/90 (32%), Positives = 45/90 (50%), Gaps = 2/90 (2%)
 Frame = +2

Query: 2335 GLGDRHPSNLMLDRLSGKILHIDFGDCFEVAMTREKFPEKIPFRLTRMLTNAMEVTGLD- 2393
            G+GDRH  NL+L   +GK+ HIDFG      + R+  P   P +L++ +  AM     D 
Sbjct: 2    GVGDRHLDNLLLTT-NGKLFHIDFG----YILGRDPKPMPPPMKLSKEMVEAMGGVSSDH 166

Query: 2394 -GNYRTTCHTVMEVLREHKDSVMAVLEAFV 2422
               +R  C+T    LR H + ++ +    V
Sbjct: 167  YHEFRKQCYTAYLHLRRHANVMLNLFSLMV 256
>18761
          Length = 492

 Score = 39.3 bits (90), Expect = 0.019,   Method: Composition-based stats.
 Identities = 26/82 (31%), Positives = 38/82 (46%), Gaps = 5/82 (6%)
 Frame = +3

Query: 2336 LGDRHPSNLMLDRLSGKILHIDFGDCF-EVAMTREKFPEKIPFRLTRMLTNAMEVTGLDG 2394
            +GDRH  N+ML + SG + HIDF     +  M      +++PF LT  +   +   G  G
Sbjct: 3    IGDRHNDNIMLKQ-SGHMFHIDFSKFLGDAQMFGNIKRDRVPFVLTPDMVFVINDGGKQG 179

Query: 2395 N----YRTTCHTVMEVLREHKD 2412
            N    +   C     +LR H D
Sbjct: 180  NRFQQFIDLCCQAFNILRTHAD 245
>05687
          Length = 1322

 Score = 37.4 bits (85), Expect = 0.071,   Method: Compositional matrix adjust.
 Identities = 20/51 (39%), Positives = 30/51 (58%)
 Frame = -1

Query: 1926 GVKAIQIDTWLQVIPQLIARIDTPRPLVGRLIHQLLTDIGRYHPQALIYPL 1976
            G+  IQ   WL  IPQL+  +       G+LI  LL+ +GR +PQA+ +P+
Sbjct: 359  GIPPIQ---WLPWIPQLLTCMVRSE---GKLIMNLLSSVGRNYPQAVYFPI 225
>05045
          Length = 2700

 Score = 31.2 bits (69), Expect = 6.3,   Method: Compositional matrix adjust.
 Identities = 18/84 (21%), Positives = 38/84 (45%)
 Frame = +1

Query: 938  MGNLPLDEFYPAVSMVALMRIFRDQSLSHHHTMVVQAITFIFKSLGLKCVQFLPQVMPTF 997
            MG      F+ +  +  L++  +  S +   +  V  +  + +S+G   + F+  + P F
Sbjct: 289  MGGPTFSPFFSSF-LTDLLKRLKQTSSTAEKSFAVGTLAEVIESIGETTIAFVDTLYPVF 465

Query: 998  LNVIRVCDGAIREFLFQQLGMLVS 1021
            L +++  D  +R      LGML +
Sbjct: 466  LRMVKEEDDEVRSNAVFALGMLAA 537
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|199559777|ref|NP_035285.2| protein phosphatase 5,
catalytic subunit [Mus musculus]
         (499 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

08242                                                                 216   2e-56
06264                                                                 214   9e-56
01173                                                                 213   2e-55
06084                                                                 185   3e-47
19040                                                                 126   2e-29
18336                                                                  97   2e-20
25536                                                                  95   8e-20
35341                                                                  75   5e-14
08670                                                                  72   5e-13
35348                                                                  68   7e-12
30337                                                                  67   2e-11
35264                                                                  64   1e-10
36367                                                                  62   7e-10
21146                                                                  60   3e-09
04645                                                                  57   2e-08
30980                                                                  54   1e-07
23484                                                                  54   2e-07
01124                                                                  53   3e-07
04295                                                                  51   1e-06
18967                                                                  50   2e-06
13560                                                                  44   1e-04
17953                                                                  41   0.001
13998                                                                  36   0.029
03857                                                                  33   0.33 
22538                                                                  30   2.2  
20748                                                                  29   4.0  
18544                                                                  28   6.7  
09861                                                                  28   8.3  
>08242
          Length = 3368

 Score =  216 bits (549), Expect = 2e-56,   Method: Compositional matrix adjust.
 Identities = 115/254 (45%), Positives = 153/254 (60%), Gaps = 6/254 (2%)
 Frame = -1

Query: 239  VCGDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFH 298
            VCGD HGQFYDL  +F++ G   +TN Y+F GDFVDRG +SVE  L L   K+ YPD   
Sbjct: 3317 VCGDIHGQFYDLKELFKVGGDVPDTN-YLFMGDFVDRGFYSVETFLLLLALKVRYPDRIT 3141

Query: 299  LLRGNHETDNMNQIYGFEGEVKAKY-TAQMYELFSEVFEWLPLAQCINGKVLIMHGGLFS 357
            L+RGNHE+  + Q+YGF  E   KY +  ++   +E+F++L L+  I+GK+  +HGGL S
Sbjct: 3140 LIRGNHESRQITQVYGFYDECLRKYGSITVWRYCTEIFDYLSLSAIIDGKIFCVHGGL-S 2964

Query: 358  EDGVTLDDIRKIERNRQPPDSGPMCDLLWSDPQPQNGRSVSKRGVSCQFGPDVTKAFLEE 417
                TLD IR I+R ++ P  GPMCDLLWSDP+   G  VS RG    FG DV   F   
Sbjct: 2963 PSIQTLDQIRSIDRKQEVPHDGPMCDLLWSDPEDMQGWGVSPRGAGYLFGSDVVSQFNAA 2784

Query: 418  NQLDYIIRSHEVKAEGYEVAHGGRCVTVFSAPNYCDQMGNKASYIHLQGSDLRPQFHQFT 477
            N +D I R+H++  EGY+       +TV+SAPNYC + GN A+ + L    L+  F  F 
Sbjct: 2783 NXIDLICRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAILELD-EHLQRDFTIFE 2607

Query: 478  AVPH-----PNVKP 486
            A P      P+ KP
Sbjct: 2606 AAPQEARGIPSKKP 2565
>06264
          Length = 999

 Score =  214 bits (544), Expect = 9e-56,   Method: Compositional matrix adjust.
 Identities = 105/227 (46%), Positives = 147/227 (64%), Gaps = 1/227 (0%)
 Frame = -3

Query: 239 VCGDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFH 298
           +CGD HGQ+YDLL +FE  G P E+N Y+F GD+VDRG  S+E I  L  +K+ YP++F 
Sbjct: 916 ICGDIHGQYYDLLRLFEYGGFPPESN-YLFLGDYVDRGRQSLETICLLLAYKIKYPENFF 740

Query: 299 LLRGNHETDNMNQIYGFEGEVKAKYTAQMYELFSEVFEWLPLAQCINGKVLIMHGGLFSE 358
           LLRGNHE  ++N+IYGF  E K +Y  ++++ F++ F  LP+A  I+ K+   HGGL S 
Sbjct: 739 LLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIIDEKIFCCHGGL-SP 563

Query: 359 DGVTLDDIRKIERNRQPPDSGPMCDLLWSDPQPQN-GRSVSKRGVSCQFGPDVTKAFLEE 417
           D  +++ IR+I R    PD G +CDLLWSDP  +  G   S RGVS  FG +V   FL +
Sbjct: 562 DLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKETMGWGESDRGVSFTFGAEVVAKFLHK 383

Query: 418 NQLDYIIRSHEVKAEGYEVAHGGRCVTVFSAPNYCDQMGNKASYIHL 464
           + LD I R+H+V  +GYE     + VT+FSAPNYC +  N  + + +
Sbjct: 382 HDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSV 242
>01173
          Length = 2619

 Score =  213 bits (541), Expect = 2e-55,   Method: Compositional matrix adjust.
 Identities = 104/227 (45%), Positives = 147/227 (64%), Gaps = 1/227 (0%)
 Frame = -1

Query: 239  VCGDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFH 298
            +CGD HGQ+YDLL +FE  G P E+N Y+F GD+VDRG  S+E I  L  +K+ YP++F 
Sbjct: 2514 ICGDIHGQYYDLLRLFEYGGFPPESN-YLFLGDYVDRGKQSLETICLLLAYKIKYPENFF 2338

Query: 299  LLRGNHETDNMNQIYGFEGEVKAKYTAQMYELFSEVFEWLPLAQCINGKVLIMHGGLFSE 358
            LLRGNHE  ++N+IYGF  E K +Y  ++++ F++ F  LP+A  I+ K+   HGGL S 
Sbjct: 2337 LLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIIDEKIFCCHGGL-SP 2161

Query: 359  DGVTLDDIRKIERNRQPPDSGPMCDLLWSDPQPQN-GRSVSKRGVSCQFGPDVTKAFLEE 417
            D  +++ IR+I R    PD G +CDLLWSDP  +  G   + RGVS  FG +V   FL +
Sbjct: 2160 DLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKETMGWGENDRGVSFTFGAEVVAKFLHK 1981

Query: 418  NQLDYIIRSHEVKAEGYEVAHGGRCVTVFSAPNYCDQMGNKASYIHL 464
            + LD I R+H+V  +GYE     + VT+FSAPNYC +  N  + + +
Sbjct: 1980 HDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSV 1840
>06084
          Length = 1739

 Score =  185 bits (470), Expect = 3e-47,   Method: Compositional matrix adjust.
 Identities = 104/238 (43%), Positives = 141/238 (59%), Gaps = 1/238 (0%)
 Frame = -2

Query: 244  HGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLRGN 303
            HGQFYDL+ +F+  G   +TN Y+F GDFVDRG FS+E    L   K  +PD   LLRGN
Sbjct: 1738 HGQFYDLMELFKTGGEMPDTN-YVFMGDFVDRGYFSLETFTLLLTLKAKWPDKIVLLRGN 1562

Query: 304  HETDNMNQIYGFEGEVKAKY-TAQMYELFSEVFEWLPLAQCINGKVLIMHGGLFSEDGVT 362
            HE+  + QIYGF  E + KY  A  +     VF+ L +A  I+  +L +HGGL S D  T
Sbjct: 1561 HESRQITQIYGFYDECQTKYGNANAWRYCCRVFDLLTIAAIIDECILCVHGGL-SPDIKT 1385

Query: 363  LDDIRKIERNRQPPDSGPMCDLLWSDPQPQNGRSVSKRGVSCQFGPDVTKAFLEENQLDY 422
            +D IR IERN++ P  G  CDL+WSDP+  +  ++S RG    FG  VT  F+  N L  
Sbjct: 1384 IDQIRTIERNQEIPHKGAFCDLVWSDPEDVDTWAMSPRGAGWLFGAKVTAEFVASNNLKL 1205

Query: 423  IIRSHEVKAEGYEVAHGGRCVTVFSAPNYCDQMGNKASYIHLQGSDLRPQFHQFTAVP 480
            I R+H++  EGY+     + VTV+SAPNYC + GN A+ +    ++   +   F AVP
Sbjct: 1204 ICRAHQLVHEGYKYMFDEKLVTVWSAPNYCYRCGNIAAVLSFTDAE-HHEAKLFKAVP 1034
>19040
          Length = 452

 Score =  126 bits (316), Expect = 2e-29,   Method: Composition-based stats.
 Identities = 56/117 (47%), Positives = 79/117 (67%)
 Frame = -3

Query: 239 VCGDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFH 298
           +CGD HGQ+ DLL +FE  G P   N Y+F GD+VDRG  S+E I  L  +K+ YP++F 
Sbjct: 375 ICGDIHGQYTDLLRLFEYGGFPPAAN-YLFLGDYVDRGKQSLETICLLLAYKIKYPENFF 199

Query: 299 LLRGNHETDNMNQIYGFEGEVKAKYTAQMYELFSEVFEWLPLAQCINGKVLIMHGGL 355
           LLRGNHE  ++N+IYGF  E K +Y  ++++ F++ F  LP+A  I+ K+   HGGL
Sbjct: 198 LLRGNHECASINRIYGFYDECKRRYNVKLWKTFTDCFNCLPVAAIIDEKIFCCHGGL 28
>18336
          Length = 465

 Score = 97.1 bits (240), Expect = 2e-20,   Method: Compositional matrix adjust.
 Identities = 44/77 (57%), Positives = 58/77 (75%)
 Frame = +2

Query: 239 VCGDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFH 298
           +CGD HGQ+YDLL +FE  G P E+N Y+F GD+VDRG  S+E I  L  +K+ YP++F 
Sbjct: 104 ICGDIHGQYYDLLRLFEYGGFPPESN-YLFLGDYVDRGKQSLETICLLLAYKIKYPENFF 280

Query: 299 LLRGNHETDNMNQIYGF 315
           LLRGNHE  ++N+IYGF
Sbjct: 281 LLRGNHECASINRIYGF 331
>25536
          Length = 486

 Score = 94.7 bits (234), Expect = 8e-20,   Method: Compositional matrix adjust.
 Identities = 54/146 (36%), Positives = 79/146 (54%), Gaps = 4/146 (2%)
 Frame = +1

Query: 192 KDLMQWYK---DQKKLHRKCAYQILVQVKEVLCXXXXXXXXXXXXXXXXXVCGDTHGQFY 248
           KDL QW +   D K+L       +  + KE+L                  VCGD HGQF+
Sbjct: 64  KDLDQWIEQLNDCKQLSENQVKTLCEKAKEIL----SKESNVQEVKCPVTVCGDVHGQFH 231

Query: 249 DLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLRGNHETDN 308
           DL+ +F + G   +TN Y+F GD+VDRG +SVE +  L   K+ + D   +LRGNHE+  
Sbjct: 232 DLMELFRIGGKSPDTN-YLFMGDYVDRGYYSVETVSLLVALKVRFRDRITILRGNHESRQ 408

Query: 309 MNQIYGFEGEVKAKY-TAQMYELFSE 333
           + Q+YGF  E   KY  A +++ F++
Sbjct: 409 ITQVYGFYDECLRKYGNANVWKYFTD 486
>35341
          Length = 641

 Score = 75.5 bits (184), Expect = 5e-14,   Method: Compositional matrix adjust.
 Identities = 34/79 (43%), Positives = 53/79 (67%)
 Frame = +3

Query: 55  IELNPGNAIYYGNRSLAYLRTECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRA 114
           ++L+P NA+   NR++A ++ E YG A  D T AI LD  Y+K Y RRAA+ + + + + 
Sbjct: 3   MDLDPTNALLPANRAMALIKMEKYGVAEVDCTTAITLDPLYVKAYLRRAAARVGMQRLQP 182

Query: 115 ALRDYETVVKVKPNDKDAK 133
           AL DYE V++++PN K A+
Sbjct: 183 ALEDYERVLQLEPNSKQAQ 239
>08670
          Length = 1307

 Score = 72.0 bits (175), Expect = 5e-13,   Method: Compositional matrix adjust.
 Identities = 40/117 (34%), Positives = 69/117 (58%)
 Frame = +3

Query: 22  DGTLKRAEELKTQANDYFKAKDYENAIKFYSQAIELNPGNAIYYGNRSLAYLRTECYGYA 81
           D T+ R+ +L  + N+  + ++Y  AI+ +++AI L+P +  + GNRS  Y R + Y  A
Sbjct: 354 DSTVLRSRQLAIRGNEMAQVEEYSAAIQLFTEAIALDPKDFRFLGNRSYCYDRLQQYEKA 533

Query: 82  LGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPNDKDAKMKYQE 138
           L DA +AI+L K + KGY+R+  +   L KF  A   +  V+K+  N ++A  + Q+
Sbjct: 534 LKDAEKAIKLSKDWPKGYFRKGRALAGLCKFSEAEESFLQVLKLDKNCEEAVQELQQ 704
>35348
          Length = 627

 Score = 68.2 bits (165), Expect = 7e-12,   Method: Compositional matrix adjust.
 Identities = 40/126 (31%), Positives = 71/126 (56%), Gaps = 5/126 (3%)
 Frame = -2

Query: 25  LKRAEELKTQANDYFKAKDYENAIKFYSQAIELNP-----GNAIYYGNRSLAYLRTECYG 79
           L  A ++K + ND FK+  Y  A++ YS+ +++ P       ++   NR+   ++ E Y 
Sbjct: 593 LAEAVKVKVRGNDTFKSGQYAEALELYSEGLDICPLKYVQQRSVMLSNRAACRIKKEDYQ 414

Query: 80  YALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPNDKDAKMKYQEC 139
            A+GD T++I+L+  YIK Y+RRA +   L K   AL+D+  VV++  +  D+    Q C
Sbjct: 413 KAVGDCTKSIDLNPAYIKAYFRRADAYEKLEKLDDALKDHRQVVEMDRSQIDS---IQAC 243

Query: 140 SKIVKQ 145
            ++ K+
Sbjct: 242 LRLEKE 225
>30337
          Length = 493

 Score = 66.6 bits (161), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 37/109 (33%), Positives = 60/109 (55%)
 Frame = -1

Query: 28  AEELKTQANDYFKAKDYENAIKFYSQAIELNPGNAIYYGNRSLAYLRTECYGYALGDATR 87
           A +LK Q N  F A+ YE+AI  Y++AI  NP  A Y+ NR+L Y++   +  A  D  R
Sbjct: 331 AIDLKNQGNKLFAARKYEDAIHCYTKAIMKNPNTATYFTNRALCYIKLRNWELASQDCQR 152

Query: 88  AIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPNDKDAKMKY 136
           A+ELD+  +KG++    + + L  +  A+     ++K     KD K+ +
Sbjct: 151 ALELDRNLVKGHFFLGQALVELAMYDEAI---THLMKAHDLAKDQKLNF 14
>35264
          Length = 867

 Score = 63.9 bits (154), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 32/94 (34%), Positives = 53/94 (56%)
 Frame = +3

Query: 39  FKAKDYENAIKFYSQAIELNPGNAIYYGNRSLAYLRTECYGYALGDATRAIELDKKYIKG 98
            +A  Y+ A++ Y+ AI L P  A YYGNR+  Y+  + Y   L DA +A++LD  ++KG
Sbjct: 72  LQAAKYKEALECYTCAINLCPSCAAYYGNRAATYMMLKKYREGLKDAQQAVQLDPTFVKG 251

Query: 99  YYRRAASNMALGKFRAALRDYETVVKVKPNDKDA 132
           Y R    ++ LG   AA  ++  V+++   +  A
Sbjct: 252 YIREGKCHLMLGNSMAASSNFNRVLELDAGNSTA 353
>36367
          Length = 827

 Score = 61.6 bits (148), Expect = 7e-10,   Method: Compositional matrix adjust.
 Identities = 43/121 (35%), Positives = 62/121 (51%), Gaps = 20/121 (16%)
 Frame = +1

Query: 352 HGGLFS---EDGVTLDDIRKIERNRQPP--DSGPMCDLLWSDP------QPQNGRSV--- 397
           HGG+ S   E G  L+ I KI      P  DS    ++LWSDP       P+  + +   
Sbjct: 1   HGGIPSPENEGGGHLEAINKIPVPLSDPEVDSPMAWEILWSDPISVDLVSPEVLKDMKEH 180

Query: 398 ------SKRGVSCQFGPDVTKAFLEENQLDYIIRSHEVKAEGYEVAHGGRCVTVFSAPNY 451
                 S+RG +  F  +   AFLE N L ++IR+HEV+  G++V   G+ +TVFS+  Y
Sbjct: 181 HGFTFNSRRGTAHFFSCNALLAFLERNGLSHVIRAHEVQEVGFQVQQQGKLLTVFSSSRY 360

Query: 452 C 452
           C
Sbjct: 361 C 363
>21146
          Length = 408

 Score = 59.7 bits (143), Expect = 3e-09,   Method: Composition-based stats.
 Identities = 25/54 (46%), Positives = 33/54 (61%)
 Frame = +3

Query: 379 GPMCDLLWSDPQPQNGRSVSKRGVSCQFGPDVTKAFLEENQLDYIIRSHEVKAE 432
           GPMCDLLWSDP  + G  +S RG    FG D+++ F   N L  I R+H++  E
Sbjct: 117 GPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNHSNGLTLISRAHQLVME 278
>04645
          Length = 1075

 Score = 57.0 bits (136), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 33/108 (30%), Positives = 55/108 (50%)
 Frame = +3

Query: 22  DGTLKRAEELKTQANDYFKAKDYENAIKFYSQAIELNPGNAIYYGNRSLAYLRTECYGYA 81
           D  + +A + + QA D       E+AI F++ AI+ NP +A+ Y  R  AYL+      A
Sbjct: 426 DDMIDQASDNRNQAMDAMAEGRLEDAIGFFTDAIKSNPTSALLYAKRGSAYLKMGKPKKA 605

Query: 82  LGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPND 129
           + D ++AIEL+    +GY  R  ++  LG +  +  D     K+  +D
Sbjct: 606 IHDCSKAIELNPDSAQGYKWRGKAHKLLGHWEESYHDLTLACKLDYDD 749
>30980
          Length = 765

 Score = 53.9 bits (128), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 28/68 (41%), Positives = 38/68 (55%)
 Frame = +3

Query: 413 AFLEENQLDYIIRSHEVKAEGYEVAHGGRCVTVFSAPNYCDQMGNKASYIHLQGSDLRPQ 472
            F   N L  I R+H++  EGY   H    VT+FSAPNYC + GN+A+ + L  + L+  
Sbjct: 3   TFNHSNGLTLISRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDA-LKYS 179

Query: 473 FHQFTAVP 480
           F QF   P
Sbjct: 180 FLQFDPAP 203
>23484
          Length = 1647

 Score = 53.5 bits (127), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 40/154 (25%), Positives = 70/154 (45%), Gaps = 7/154 (4%)
 Frame = +1

Query: 21  ADGTLKRAEELKTQANDYFKAKDYENAIKFYSQAIELNP----GNAIYYGNRSLAYLRTE 76
           ++  + RAE  + + ND FK KDY  A+  Y + I+ N      NA+ Y NR+ A+    
Sbjct: 478 SEDPVARAESYREEGNDLFKKKDYRLAVDNYXEGIKSNSPQRLQNAVLYTNRAAAHFHLG 657

Query: 77  CYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPNDK---DAK 133
            Y  A  D   A +    ++K   R A     + K    LR  +  + V+P  K   D K
Sbjct: 658 NYRSAFNDCFAARKFKPDHLKALVRGAMCCDKMNKHNDTLRWCDAGLMVEPGHKDLTDLK 837

Query: 134 MKYQECSKIVKQKAFERAIAGDEHRRSVVDSLDI 167
           +K  +  +I ++   ++A+   +   + +  LD+
Sbjct: 838 VKATKAKRIQERDERKQALKEKKEEEATLKLLDV 939
>01124
          Length = 1372

 Score = 52.8 bits (125), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 30/122 (24%), Positives = 60/122 (49%), Gaps = 8/122 (6%)
 Frame = -3

Query: 31  LKTQANDYFKAKDYENAIKFYSQAIELNPGNAIYYGNRSLAYLRTECYGYALGDATRAIE 90
           L+ + N +F + +Y+ A+  Y+ A+ LNP     Y NR+  +L+       + D ++A++
Sbjct: 746 LRDKGNGFFASGNYQAAVNVYTHALRLNPKMPSLYSNRAACHLKLRNLFKCIEDCSKAMD 567

Query: 91  L--------DKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPNDKDAKMKYQECSKI 142
           L            +K   RR  +   L  +   L+DYE  +K+ PN++  K   ++  +I
Sbjct: 566 LLSPPVPQNAASRVKAMVRRGTAFCQLEMYVEGLQDYEAALKLDPNNQQLKEDAEKMRQI 387

Query: 143 VK 144
           ++
Sbjct: 386 IQ 381
>04295
          Length = 748

 Score = 50.8 bits (120), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 23/56 (41%), Positives = 32/56 (57%)
 Frame = -1

Query: 409 DVTKAFLEENQLDYIIRSHEVKAEGYEVAHGGRCVTVFSAPNYCDQMGNKASYIHL 464
           DV   FL  + LD I R+H+V  +GYE     + VT+FSAPNYC +  N    + +
Sbjct: 745 DVVSKFLNRHDLDLITRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSV 578
>18967
          Length = 440

 Score = 50.1 bits (118), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 26/61 (42%), Positives = 37/61 (60%)
 Frame = +2

Query: 420 LDYIIRSHEVKAEGYEVAHGGRCVTVFSAPNYCDQMGNKASYIHLQGSDLRPQFHQFTAV 479
           LD I R+H++  EG +    G+ VTV+SAPNYC + GN A+ +  + +  R Q   F AV
Sbjct: 2   LDLICRAHQLVNEGIKYMFEGKLVTVWSAPNYCYRCGNVAAILSFETAQQR-QTKIFLAV 178

Query: 480 P 480
           P
Sbjct: 179 P 181
>13560
          Length = 978

 Score = 43.9 bits (102), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 20/66 (30%), Positives = 38/66 (57%)
 Frame = +1

Query: 65  YGNRSLAYLRTECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVK 124
           Y N +   +++  + + + + T A+ LD   +K  YRRA++N+ LG    A  D ET ++
Sbjct: 358 YLNLAACQIKSGHHKHVITNCTHALNLDPANVKALYRRASANVNLGNLLHAHEDLETGLQ 537

Query: 125 VKPNDK 130
            +PN++
Sbjct: 538 KEPNNR 555
>17953
          Length = 626

 Score = 40.8 bits (94), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 20/54 (37%), Positives = 29/54 (53%), Gaps = 6/54 (11%)
 Frame = -2

Query: 415 LEENQLDYIIRSHEVKAEGYEVAHGGRC------VTVFSAPNYCDQMGNKASYI 462
           L++N L  IIR+HE +  GY +    +       +T+FSAPNY D   NK   +
Sbjct: 625 LQQNNLLSIIRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKVQLL 464
>13998
          Length = 1075

 Score = 36.2 bits (82), Expect = 0.029,   Method: Compositional matrix adjust.
 Identities = 17/45 (37%), Positives = 27/45 (60%)
 Frame = +1

Query: 81  ALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKV 125
           A+ D  R ++L+ +Y+K    RA  N  L KF  A+ DYET +++
Sbjct: 1   AVADCNRVLDLNSQYLKALLLRARCNNDLEKFEEAVADYETALQL 135
>03857
          Length = 1696

 Score = 32.7 bits (73), Expect = 0.33,   Method: Compositional matrix adjust.
 Identities = 18/80 (22%), Positives = 36/80 (45%)
 Frame = +1

Query: 67  NRSLAYLRTECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVK 126
           N +   L+   Y  AL      +E D    K  YR+  ++     +  AL  ++  +   
Sbjct: 637 NAAACCLKLNKYNEALEYCQEVLEADPDNSKAQYRQGQAHAGNKDYETALASFQKALAAN 816

Query: 127 PNDKDAKMKYQECSKIVKQK 146
           P+DK  K++ Q+  + V+++
Sbjct: 817 PDDKGIKLEIQKVKRTVEEE 876
>22538
          Length = 1255

 Score = 30.0 bits (66), Expect = 2.2,   Method: Compositional matrix adjust.
 Identities = 23/79 (29%), Positives = 37/79 (46%), Gaps = 1/79 (1%)
 Frame = +1

Query: 276 GSFSVEVILTLFGFKLLYP-DHFHLLRGNHETDNMNQIYGFEGEVKAKYTAQMYELFSEV 334
            +F+ ++I  +F     +P  HF L +         QI+  +  +  + T    +L S V
Sbjct: 451 STFADKIIFLVFSKHACWP*PHFILQKLVMRVQFSXQIFQ-KSAIVVQQTQVCLQLLS-V 624

Query: 335 FEWLPLAQCINGKVLIMHG 353
           F WL L QC+N    I+HG
Sbjct: 625 FRWLSLHQCLN---FIIHG 672
>20748
          Length = 847

 Score = 29.3 bits (64), Expect = 4.0,   Method: Compositional matrix adjust.
 Identities = 20/79 (25%), Positives = 36/79 (45%)
 Frame = -2

Query: 361 VTLDDIRKIERNRQPPDSGPMCDLLWSDPQPQNGRSVSKRGVSCQFGPDVTKAFLEENQL 420
           V  +DI ++ +      S P C L    P    GR + K+G+       V K F+++++ 
Sbjct: 729 VACEDIVRVMQTEAKALSRPECPLRILCPNNLCGRIIGKKGI-------VIKGFMDKSKT 571

Query: 421 DYIIRSHEVKAEGYEVAHG 439
           + ++ S E  A  Y  + G
Sbjct: 570 NIVVSSFE--ASPYPTSMG 520
>18544
          Length = 456

 Score = 28.5 bits (62), Expect = 6.7,   Method: Composition-based stats.
 Identities = 12/37 (32%), Positives = 19/37 (51%)
 Frame = -2

Query: 29  EELKTQANDYFKAKDYENAIKFYSQAIELNPGNAIYY 65
           E L T   DY+  +D E   K + Q +++  G + YY
Sbjct: 428 EVLGTSGYDYYHPEDIERVSKCHEQLMQMGEGTSCYY 318
>09861
          Length = 1182

 Score = 28.1 bits (61), Expect = 8.3,   Method: Compositional matrix adjust.
 Identities = 11/19 (57%), Positives = 13/19 (68%)
 Frame = -1

Query: 432  EGYEVAHGGRCVTVFSAPN 450
            EGYE     RCVTV++ PN
Sbjct: 1170 EGYETTGKNRCVTVYALPN 1114
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|21703726|ref|NP_663335.1| isopentenyl-diphosphate
delta isomerase isoform 1 [Mus musculus]
         (227 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

32818                                                                 134   2e-56
>32818
          Length = 715

 Score =  134 bits (336), Expect(2) = 2e-56,   Method: Compositional matrix adjust.
 Identities = 66/109 (60%), Positives = 85/109 (77%), Gaps = 3/109 (2%)
 Frame = -2

Query: 74  KITFPGCFTNSCCSHPLSNPGELEENNAIGVKRAAKRRLKAELGIPLEEVDLNEMDYLTR 133
           K TFPG FTN+CCSHPL+  GE EE NA+GV RAA+R+LK ELGI  ++V L +  YLTR
Sbjct: 327 KNTFPGHFTNTCCSHPLNFDGEKEETNALGVCRAAQRKLKHELGIEPDQVPLEDFHYLTR 148

Query: 134 IYYKAQS---DGIWGEHEVDYILFLRKNVTLNPDPNEIKSYCYVSKEEV 179
           I+YKA +   DG W EHE+DYILF++++VT+ P  NE+KSY YVSK+E+
Sbjct: 147 IHYKAGNVPQDGKWAEHEIDYILFIQRDVTVVPSVNEVKSYRYVSKDEL 1

 Score =  102 bits (254), Expect(2) = 2e-56,   Method: Compositional matrix adjust.
 Identities = 46/69 (66%), Positives = 59/69 (85%)
 Frame = -3

Query: 9   LDEKQVQLLAEMCILIDENDNKIGADTKKNCHLNENIDKGLLHRAFSVFLFNTENKLLLQ 68
           LD+ Q++L+ E CIL+D+ND  IG+ +KK CHL ENI+KG+LHRAFSVFLFN++ +LLLQ
Sbjct: 521 LDQTQIELMKEECILVDDNDTNIGSASKKVCHLLENINKGMLHRAFSVFLFNSQGELLLQ 342

Query: 69  QRSDAKITF 77
           QRSDAKI F
Sbjct: 341 QRSDAKIHF 315
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|7242197|ref|NP_035315.1| proteasome (prosome,
macropain) subunit, beta type 1 [Mus musculus]
         (240 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

00497                                                                 214   2e-56
09425                                                                  77   8e-15
06516                                                                  69   2e-12
03425                                                                  37   0.005
19360                                                                  37   0.006
13884                                                                  28   3.2  
24645                                                                  28   4.9  
>00497
          Length = 1184

 Score =  214 bits (545), Expect = 2e-56,   Method: Compositional matrix adjust.
 Identities = 97/153 (63%), Positives = 125/153 (81%)
 Frame = +3

Query: 88  CLTLTKIIEARLKMYKHSNNKAMTTGAIAAMLSTILYSRRFFPYYVYNIIGGLDEEGKGA 147
            LTLTK++E RLKM+ + +NK M T ++AAMLSTILY RRFFPYY YNI+ GLD EGKG 
Sbjct: 3   VLTLTKVVETRLKMFSYIHNKEMDTSSVAAMLSTILYYRRFFPYYXYNIVAGLDTEGKGC 182

Query: 148 VYSFDPVGSYQRDSFKAGGSASAMLQPLLDNQVGFKNMQNVEHVPLTLDRAMRLVKDVFI 207
           V+SFDPVGSY+R++++AGGSAS+MLQPLLDNQ+G KN    + VPL+  +A+ LVKDVF 
Sbjct: 183 VFSFDPVGSYERETYRAGGSASSMLQPLLDNQIGMKNQAGAKQVPLSQAKAVALVKDVFT 362

Query: 208 SAAERDVYTGDALRICIVTKEGIREETVPLRKD 240
           SAAERD+ TGDA+ I +V+K+G+ + T PLR+D
Sbjct: 363 SAAERDINTGDAVVIHVVSKQGVTKTTFPLRRD 461
>09425
          Length = 1898

 Score = 76.6 bits (187), Expect = 8e-15,   Method: Compositional matrix adjust.
 Identities = 51/216 (23%), Positives = 101/216 (46%), Gaps = 2/216 (0%)
 Frame = -3

Query: 27   LRFSPYAFNGGTVLAIAGEDFSIVASDTRLSEGFSIHTRDSPKCYKLTDKTVIGCSGFHG 86
            ++ S  A+NG  ++A+ G+D   +A+D R        + D  K +++     IG  G   
Sbjct: 1842 VQMSILAYNGAAIIAMKGKDCVAIAADRRFGVQAQTVSMDFDKVFEMGPHLFIGLPGLAT 1663

Query: 87   DCLTLTKIIEARLKMYKHSNNKAMTTGAIAAMLSTILYSRRFFPYYVYNIIGGLDEEG-K 145
            D  T+++ ++ RL +Y+   N+ +      +M+S +LY RRF PY+V  +I GL+ +  K
Sbjct: 1662 DVQTVSQRLKFRLNLYELRENRRIKPQTFMSMVSNLLYERRFGPYFVEPVIAGLEPKTFK 1483

Query: 146  GAVYSFDPVGS-YQRDSFKAGGSASAMLQPLLDNQVGFKNMQNVEHVPLTLDRAMRLVKD 204
              + S D +G     + F   G+ S  +         +   +++    L  D     +  
Sbjct: 1482 PYIASMDLIGCPMVTEDFVVSGTCSEQM---------YGMCESLWEPDLEPDDLFETISQ 1330

Query: 205  VFISAAERDVYTGDALRICIVTKEGIREETVPLRKD 240
              ++A +RD  +G    + I+ K+ + ++ +  R D
Sbjct: 1329 ALMNAFDRDAVSGWGGVVYIIEKDKVTKKLLKTRMD 1222
>06516
          Length = 835

 Score = 68.6 bits (166), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 54/201 (26%), Positives = 85/201 (42%)
 Frame = +1

Query: 35  NGGTVLAIAGEDFSIVASDTRLSEGFSIHTRDSPKCYKLTDKTVIGCSGFHGDCLTLTKI 94
            G T++A+  ED  ++ +D+R + G  I  R + K  K+TD+     SG   D   +  I
Sbjct: 118 TGTTIMAVEYEDGVVIGADSRTTTGAYIANRVTDKLTKVTDRIYCCRSGSAADTQAIADI 297

Query: 95  IEARLKMYKHSNNKAMTTGAIAAMLSTILYSRRFFPYYVYNIIGGLDEEGKGAVYSFDPV 154
           ++  L  Y+    +       A +   + Y  R        I+ G D+   G VYS    
Sbjct: 298 VKYHLDFYRMEMGEEPQVQTAANVFRELCYDNRD-SLTAGIIVAGWDKRTGGQVYSVPIG 474

Query: 155 GSYQRDSFKAGGSASAMLQPLLDNQVGFKNMQNVEHVPLTLDRAMRLVKDVFISAAERDV 214
           G  QR  F  GGS S  L   +D Q  FK         +  D  ++ V      A  RD 
Sbjct: 475 GMLQRQPFAIGGSGSTYLYGYVDAQ--FKP-------SMKKDDCLKFVSQAVSLAINRDG 627

Query: 215 YTGDALRICIVTKEGIREETV 235
            +G  +R+ ++ KEG+   T+
Sbjct: 628 SSGGIIRMAVINKEGVERVTL 690
>03425
          Length = 933

 Score = 37.4 bits (85), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 26/95 (27%), Positives = 47/95 (49%)
 Frame = +3

Query: 136 IIGGLDEEGKGAVYSFDPVGSYQRDSFKAGGSASAMLQPLLDNQVGFKNMQNVEHVPLTL 195
           ++GG+D  G   +YS  P GS  +  F   GS S       +++  FK         ++ 
Sbjct: 18  VLGGVDVTGP-HLYSIWPHGSTDKLPFVTMGSGSLAAMATFEDR--FKP-------DMSR 167

Query: 196 DRAMRLVKDVFISAAERDVYTGDALRICIVTKEGI 230
           D AM+LV+D   +    D+ +G  + +C++TK+ +
Sbjct: 168 DEAMKLVRDAIAAGIFNDLGSGSNIDLCVITKDKV 272
>19360
          Length = 569

 Score = 37.4 bits (85), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 37/144 (25%), Positives = 56/144 (38%)
 Frame = +2

Query: 87  DCLTLTKIIEARLKMYKHSNNKAMTTGAIAAMLSTILYSRRFFPYYVYNIIGGLDEEGKG 146
           D   +  I+   L  +++  +K       A+      Y+ R        I+ G DEE  G
Sbjct: 11  DTQAIADIVAYSLNYHRNQTSKEPLVWEAASEFRNFCYNYRD-SLLAGIIVAGWDEERGG 187

Query: 147 AVYSFDPVGSYQRDSFKAGGSASAMLQPLLDNQVGFKNMQNVEHVPLTLDRAMRLVKDVF 206
            VYS    G   R+S   GGS S+ +        GF        +P   +  +  VK   
Sbjct: 188 QVYSVPLGGMLTRESCTIGGSGSSFI-------YGFVREHYRPGMP--KEECIEFVKKAV 340

Query: 207 ISAAERDVYTGDALRICIVTKEGI 230
             A   D  +G  +RI I+ K+GI
Sbjct: 341 QHAIFHDGSSGGVVRIGIIDKDGI 412
>13884
          Length = 1423

 Score = 28.1 bits (61), Expect = 3.2,   Method: Compositional matrix adjust.
 Identities = 20/77 (25%), Positives = 30/77 (38%), Gaps = 6/77 (7%)
 Frame = -2

Query: 18   PHGSAGPVQLRFSPYAFNGG------TVLAIAGEDFSIVASDTRLSEGFSIHTRDSPKCY 71
            P        L  S Y F  G      T   +  +  +  A D+  +   S HT+D P C+
Sbjct: 1182 PRAKKVECSLCKSSYCFRCGIEYHAPTDCDVIKKWLTKCADDSETANYISAHTKDCPSCH 1003

Query: 72   KLTDKTVIGCSGFHGDC 88
               +K+  GC+  H  C
Sbjct: 1002 VCIEKSA-GCN--HMQC 961
>24645
          Length = 1071

 Score = 27.7 bits (60), Expect = 4.9,   Method: Compositional matrix adjust.
 Identities = 17/59 (28%), Positives = 32/59 (54%)
 Frame = -1

Query: 165 GGSASAMLQPLLDNQVGFKNMQNVEHVPLTLDRAMRLVKDVFISAAERDVYTGDALRIC 223
           GG   +  + LL ++VG K+ +  +     LDRA+++ K    +  + +V+ G ALR+ 
Sbjct: 735 GGGQKSRKELLLAHRVGKKSRKRQK----KLDRALQVAKRKKKNREKAEVFDGSALRMV 571
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|160708010|ref|NP_032466.2| kinesin family member 1A
isoform a [Mus musculus]
         (1697 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

33215                                                                 217   4e-56
38050                                                                 106   5e-56
12048                                                                 135   4e-36
34477                                                                 108   2e-33
13148                                                                 124   2e-32
11818                                                                 109   1e-29
28434                                                                 128   2e-29
14618                                                                 102   1e-21
02896                                                                 101   2e-21
34899                                                                  96   1e-19
15043                                                                  95   3e-19
17748                                                                  68   3e-11
36593                                                                  50   9e-06
38061                                                                  43   9e-04
18965                                                                  36   0.16 
08095                                                                  33   0.73 
>33215
          Length = 696

 Score =  217 bits (552), Expect = 4e-56,   Method: Compositional matrix adjust.
 Identities = 119/244 (48%), Positives = 157/244 (64%), Gaps = 2/244 (0%)
 Frame = +1

Query: 146 YMEIYCERVRDLLNPKNKGNLRVREHPLLGPYVEDLSKLAVTSYNDIQDLMDSGNKARTV 205
           Y+EIY E +RDLL+      L ++  P  G YV+DLS     S  +I+ +M+ GN+ R+V
Sbjct: 1   YLEIYQEEIRDLLSKDQSKRLELKXRPDTGVYVKDLSSFVTKSVREIEHVMNVGNQNRSV 180

Query: 206 AATNMNETSSRSHAVFNIIF--TQKRHDAETNITTEKVSKISLVDLAGSERADSTGAKGT 263
            ATNMNE SSRSHA+F I    ++   D E +I   +V K+++VDLAGSER   TGA G 
Sbjct: 181 GATNMNEHSSRSHAIFIITVECSEIGADGENHI---RVGKLNMVDLAGSERQAKTGATGD 351

Query: 264 RLKEGANINKSLTTLGKVISALAEMDSGPXXXXXXXXTDFIPYRDSVLTWLLRENLGGNS 323
           RLKE   IN SL+ L  VISAL +             T  IPYRDS LT LL+++LGGNS
Sbjct: 352 RLKEATKINLSLSALSNVISALVD-----------AKTTHIPYRDSKLTRLLQDSLGGNS 498

Query: 324 RTAMVAALSPADINYDETLSTLRYADRAKQIRCNAIINEDPNNKLIRELKDEVTRLRDLL 383
           +T MVA + PA  N+DETL+TLRYA+RAK I+    INEDP + L+RE +DE+ RL++ L
Sbjct: 499 KTTMVANIGPASYNFDETLTTLRYANRAKSIKNKPKINEDPKDALLREFQDEINRLKNQL 678

Query: 384 YAQG 387
             +G
Sbjct: 679 SEKG 690
>38050
          Length = 809

 Score =  106 bits (264), Expect(3) = 5e-56,   Method: Composition-based stats.
 Identities = 60/109 (55%), Positives = 74/109 (67%)
 Frame = -2

Query: 160 PKNKGNLRVREHPLLGPYVEDLSKLAVTSYNDIQDLMDSGNKARTVAATNMNETSSRSHA 219
           PK KG LR+R+HP  G Y + L  + V SY DI+  M++G   RTVAATNMN TSSR+H 
Sbjct: 748 PK-KGGLRIRQHPKNGFYADGLQVVPVVSYEDIEKKMEAGTTNRTVAATNMNATSSRAHT 572

Query: 220 VFNIIFTQKRHDAETNITTEKVSKISLVDLAGSERADSTGAKGTRLKEG 268
           +  I F QK  +A    TT K + I+LVDLAGSERADSTGA GT  ++G
Sbjct: 571 IVGITFMQKFKNAAGEETT-KSALINLVDLAGSERADSTGATGTD*RKG 428

 Score = 96.7 bits (239), Expect(3) = 5e-56,   Method: Compositional matrix adjust.
 Identities = 45/64 (70%), Positives = 56/64 (87%)
 Frame = -3

Query: 320 GGNSRTAMVAALSPADINYDETLSTLRYADRAKQIRCNAIINEDPNNKLIRELKDEVTRL 379
           G NS+T MVAALSPADINY+ETLSTLRYADRAKQI+  A++NEDP +KLIREL++E  +L
Sbjct: 300 GWNSKTIMVAALSPADINYEETLSTLRYADRAKQIKTKAMVNEDPTDKLIRELQEENDKL 121

Query: 380 RDLL 383
           + +L
Sbjct: 120 KAML 109

 Score = 56.6 bits (135), Expect(3) = 5e-56,   Method: Composition-based stats.
 Identities = 31/63 (49%), Positives = 38/63 (60%)
 Frame = -1

Query: 262 GTRLKEGANINKSLTTLGKVISALAEMDSGPXXXXXXXXTDFIPYRDSVLTWLLRENLGG 321
           G RLKEGA IN+SL+ LG  ISALA+   G            +P+RDS LT LL+  LGG
Sbjct: 449 GDRLKEGAAINQSLSCLGNCISALADKAGGKNVK--------VPFRDSALTKLLKNALGG 294

Query: 322 NSR 324
            +R
Sbjct: 293 TAR 285
>12048
          Length = 1162

 Score =  135 bits (339), Expect(2) = 4e-36,   Method: Compositional matrix adjust.
 Identities = 92/268 (34%), Positives = 141/268 (52%), Gaps = 8/268 (2%)
 Frame = +2

Query: 100 GAGKSYTMMGKQEK-DQQGIIPQLCEDLFSRINDTTNDNMSYSVEVSYMEIYCERVRDLL 158
           G GK++T+ G  E+   +G+IP+    ++ +     N  +S++V +SY+EIY +   DLL
Sbjct: 410 GGGKTFTITGGAERYMDRGLIPRSLSYIYEQTEK--NPELSFTVHISYLEIYNDSGYDLL 583

Query: 159 NPKNKG-------NLRVREHPLLGPYVEDLSKLAVTSYNDIQDLMDSGNKARTVAATNMN 211
           +PK++         + + E      ++ +LS     S  +  +L+  G+  R +A T MN
Sbjct: 584 DPKHEAAKLEDLPKVNLLEDSDQNIHLRNLSVHQANSEEEALNLLFLGDTNRMIAETPMN 763

Query: 212 ETSSRSHAVFNIIFTQKRHDAETNITTEKVSKISLVDLAGSERADSTGAKGTRLKEGANI 271
           + SSRSH +F I  T +    ET   T + +K  LVDLAGSER   T   G  L E   I
Sbjct: 764 QASSRSHCIFTIHITTR----ETGSATIRRAKYHLVDLAGSERVAKTNVNGQLLTEARYI 931

Query: 272 NKSLTTLGKVISALAEMDSGPXXXXXXXXTDFIPYRDSVLTWLLRENLGGNSRTAMVAAL 331
           N SL  L  VI AL+E                +PYR+S++T +LR++LGGN  T M+A  
Sbjct: 932 NSSLHFLELVIIALSE-----------KSRQHVPYRNSMMTSVLRDSLGGNCMTTMIATC 1078

Query: 332 SPADINYDETLSTLRYADRAKQIRCNAI 359
           S    N DE++ST R+A R   I+ + +
Sbjct: 1079SMEKRNMDESISTCRFAQRVAMIKNDVL 1162

 Score = 37.0 bits (84), Expect(2) = 4e-36,   Method: Composition-based stats.
 Identities = 12/32 (37%), Positives = 24/32 (75%)
 Frame = +1

Query: 69  SQKQVYRDIGEEMLQHAFEGYNVCIFAYGQTG 100
           +Q +V++++ + ++ +  +GYN  +FAYGQTG
Sbjct: 316 NQDEVFQNVAKPVIDNVLQGYNGTVFAYGQTG 411
>34477
          Length = 811

 Score =  108 bits (269), Expect(2) = 2e-33,   Method: Compositional matrix adjust.
 Identities = 69/153 (45%), Positives = 84/153 (54%), Gaps = 9/153 (5%)
 Frame = +3

Query: 240 KVSKISLVDLAGSERADSTGAKGTRLKEGANINKSLTTLGKVISALAEMDSGPXXXXXXX 299
           +V K+ LVDLAGSER   TGA G RLKE   IN SL+TLG VIS                
Sbjct: 189 RVGKLHLVDLAGSERQAKTGATGQRLKEATKINLSLSTLGNVIS---------------- 320

Query: 300 XTDFIPYRDSVLTWLLRE--------NLGGNS-RTAMVAALSPADINYDETLSTLRYADR 350
               +P      T  L+E         L G   +T MVA + PAD NYDET+STLRYA+R
Sbjct: 321 ----VPGGRQEHTHPLQELQAHSPAAGLPGRQLQTVMVANMGPADYNYDETISTLRYANR 488

Query: 351 AKQIRCNAIINEDPNNKLIRELKDEVTRLRDLL 383
           AK I+  A INEDP + L+R+ + E+  LR  L
Sbjct: 489 AKNIKNKAKINEDPKDALLRQFQKEIEELRKQL 587

 Score = 55.1 bits (131), Expect(2) = 2e-33,   Method: Composition-based stats.
 Identities = 24/47 (51%), Positives = 33/47 (70%)
 Frame = +1

Query: 177 YVEDLSKLAVTSYNDIQDLMDSGNKARTVAATNMNETSSRSHAVFNI 223
           YV+DLS   V + +D+  +M  GNK R+V +TNMN  SSRSHA+F +
Sbjct: 4   YVKDLSAFVVNNADDMDRIMTLGNKNRSVGSTNMNMHSSRSHAIFTV 144
>13148
          Length = 653

 Score =  124 bits (312), Expect(2) = 2e-32,   Method: Composition-based stats.
 Identities = 73/173 (42%), Positives = 108/173 (62%), Gaps = 1/173 (0%)
 Frame = -3

Query: 103 KSYTMMGKQEKDQ-QGIIPQLCEDLFSRINDTTNDNMSYSVEVSYMEIYCERVRDLLNPK 161
           K++TM G    +  QGIIP++ +D+F+ I    ++N+ + ++VSY EIY +++RDLL+  
Sbjct: 501 KTHTMEGVLGNESLQGIIPRIVQDIFNYIYGM-DENLEFHIKVSYFEIYMDKIRDLLD-V 328

Query: 162 NKGNLRVREHPLLGPYVEDLSKLAVTSYNDIQDLMDSGNKARTVAATNMNETSSRSHAVF 221
            K NL V E     PYV+  ++  V+S  ++ +++D G   R VA TNMNE SSRSH+VF
Sbjct: 327 TKTNLSVHEDKNRVPYVKGCTERFVSSPEEVMEVVDEGKSNRHVAVTNMNEHSSRSHSVF 148

Query: 222 NIIFTQKRHDAETNITTEKVSKISLVDLAGSERADSTGAKGTRLKEGANINKS 274
            I   Q+  D+E  +      K+ LVDLAGSE+   TGA+G  L E  NIN+S
Sbjct: 147 LIHVKQENVDSEKKLH----GKLYLVDLAGSEKVSKTGAEGAVLDEAKNINRS 1

 Score = 34.7 bits (78), Expect(2) = 2e-32,   Method: Composition-based stats.
 Identities = 15/35 (42%), Positives = 21/35 (60%)
 Frame = -1

Query: 69  SQKQVYRDIGEEMLQHAFEGYNVCIFAYGQTGAGK 103
           +Q+ VY    + ++     GYN  IFAYGQT +GK
Sbjct: 602 TQEYVYTVTAKPIVADVLSGYNGTIFAYGQTSSGK 498
>11818
          Length = 657

 Score =  109 bits (272), Expect(2) = 1e-29,   Method: Compositional matrix adjust.
 Identities = 69/178 (38%), Positives = 102/178 (57%), Gaps = 7/178 (3%)
 Frame = -1

Query: 101 AGKSYTMMG------KQEKDQQGIIPQLCEDLFSRINDTTNDNMSYSVEVSYMEIYCERV 154
           +GK+YTM G        + D  GIIP++  DLF+ I + ++   ++ V VSY+EIY E +
Sbjct: 657 SGKTYTMGGCYDAALSHDDDLVGIIPRILGDLFNGIAERSD--YTFKVTVSYLEIYNEDL 484

Query: 155 RDLLN-PKNKGNLRVREHPLLGPYVEDLSKLAVTSYNDIQDLMDSGNKARTVAATNMNET 213
            DLL  P  +  L +RE       ++ L ++ V S  D    +  G ++RT  AT MN+T
Sbjct: 483 LDLLCLPSQRQPLSIREEMNGEIKIKGLKEVEVGSLEDTLMCLSQGARSRTTGATAMNDT 304

Query: 214 SSRSHAVFNIIFTQKRHDAETNITTEKVSKISLVDLAGSERADSTGAKGTRLKEGANI 271
           SSRSHA+F +   + + +   ++    ++K  LVDLAGSERA  T A+G R KEG NI
Sbjct: 303 SSRSHAIFTVHIEKSKKE---DMNDHCIAKFHLVDLAGSERAKKTRAEGDRFKEGVNI 139

 Score = 41.2 bits (95), Expect(2) = 1e-29,   Method: Composition-based stats.
 Identities = 25/53 (47%), Positives = 29/53 (54%)
 Frame = -3

Query: 273 KSLTTLGKVISALAEMDSGPXXXXXXXXTDFIPYRDSVLTWLLRENLGGNSRT 325
           + L  LG VISAL E                IPYRDS LT LL+++LGGNS T
Sbjct: 136 RGLLALGNVISALGE---------DVQKRGHIPYRDSKLTRLLQDSLGGNSHT 5
>28434
          Length = 777

 Score =  128 bits (321), Expect = 2e-29,   Method: Compositional matrix adjust.
 Identities = 72/138 (52%), Positives = 89/138 (64%)
 Frame = +2

Query: 248 DLAGSERADSTGAKGTRLKEGANINKSLTTLGKVISALAEMDSGPXXXXXXXXTDFIPYR 307
           DLAGSERA  T A+G R KEG NIN+ L  LG VISAL E                IPYR
Sbjct: 62  DLAGSERAKRTRAEGDRFKEGVNINRGLLALGNVISALGE---------DVQKRGHIPYR 214

Query: 308 DSVLTWLLRENLGGNSRTAMVAALSPADINYDETLSTLRYADRAKQIRCNAIINEDPNNK 367
           DS LT LL+++LGGNS T MVA +SPAD N +ETL+TLRYADRA++I+   +IN DP + 
Sbjct: 215 DSKLTRLLQDSLGGNSHTLMVACVSPADSNMEETLNTLRYADRARKIKNKPVINRDPQS- 391

Query: 368 LIRELKDEVTRLRDLLYA 385
                 DE+ RLR ++ +
Sbjct: 392 ------DEILRLRQVVQS 427
>14618
          Length = 724

 Score =  102 bits (254), Expect = 1e-21,   Method: Compositional matrix adjust.
 Identities = 73/235 (31%), Positives = 120/235 (51%), Gaps = 24/235 (10%)
 Frame = -2

Query: 4   ASVKVAVRVRPFNSREMSRDSKCI------------------IQMSGSTTTIVNPKQPKE 45
            +++V  RVRP    E + +   I                   +MS + +T+ N ++   
Sbjct: 672 GNIRVFCRVRPLLGEEAATNDGVIHHINFPDSDNKVLELDRLTEMSMNESTLYNNRRGN- 496

Query: 46  TPKSFSFDYSYWSHTSPEDINYASQKQVYRDIGEEMLQHAFEGYNVCIFAYGQTGAGKSY 105
               FSFD  +     P++    +Q+ V+ +I + ++Q A +GYNVCIFAYGQTG+GK+Y
Sbjct: 495 NKYEFSFDRVF----HPDN----TQQDVFEEISQ-LVQSALDGYNVCIFAYGQTGSGKTY 343

Query: 106 TMMGK--QEKDQQGIIPQLCEDLFSRINDTTNDNMSYSVEVSYMEIYCERVRDLLNPKNK 163
           TM G    ++D +G+IP+    +FS   +  +    Y    S++EIY E + DLL+    
Sbjct: 342 TMEGGLVGDEDTKGMIPRAVSQIFSTARELQDKGWQYKFTTSFVEIYNEMIGDLLSSNKX 163

Query: 164 GNLRVREHPLLG----PYVEDLSKLAVTSYNDIQDLMDSGNKARTVAATNMNETS 214
            N++  E  + G      V +L+ + VTS ++I  L+   ++ R VAAT  NE S
Sbjct: 162 KNVK-HEIRMAGRDNNVAVTNLTTVDVTSQHEIAKLLRQASENRAVAATKCNERS 1
>02896
          Length = 2076

 Score =  101 bits (252), Expect = 2e-21,   Method: Compositional matrix adjust.
 Identities = 67/190 (35%), Positives = 107/190 (56%), Gaps = 3/190 (1%)
 Frame = +1

Query: 194 DLMDSGNKARTVAATNMNETSSRSHAVFNIIF-TQKRHDAETNITTEKVSKISLVDLAGS 252
           +L+  G   R++AA ++N  SSRSH +F +   ++ R  +    T   VSK++ VDLAGS
Sbjct: 64  NLLFEGETNRSIAAHSLNRMSSRSHCIFTVYLESRSRVQSSAKYT---VSKLNFVDLAGS 234

Query: 253 ERADSTGAKGTRLKEGANINKSLTTLGKVISALAEMDSGPXXXXXXXXTDFIPYRDSVLT 312
           ER   + ++G  + E   INKSL+ L +V+ ALA+ +            D IP+R S LT
Sbjct: 235 ERIGKSKSEGKMVTEAMYINKSLSFLEQVVIALADKNR-----------DHIPFRQSKLT 381

Query: 313 WLLRENLGGNSRTAMVAALSPADINYDETLSTLRYADRAKQIRCNAIINE--DPNNKLIR 370
             L++++GGN  T ++A +       +ET+STLR+A R   +     INE  DP   L++
Sbjct: 382 HYLKDSIGGNCNTVLIANVWGERAQLEETVSTLRFATRMMCVANEPAINEVYDP-ALLVK 558

Query: 371 ELKDEVTRLR 380
           +L+ E+  L+
Sbjct: 559 KLQREINHLK 588
>34899
          Length = 564

 Score = 96.3 bits (238), Expect = 1e-19,   Method: Compositional matrix adjust.
 Identities = 54/154 (35%), Positives = 89/154 (57%), Gaps = 1/154 (0%)
 Frame = +3

Query: 68  ASQKQVYRDIGEEMLQHAFEGYNVCIFAYGQTGAGKSYTMMGKQEKDQQ-GIIPQLCEDL 126
           A   Q+Y++  + M+Q A EGYNV I A+G TG+GKS+ M G    DQ+ G+ P + + L
Sbjct: 30  AKNGQIYQEKCDSMVQRALEGYNVTIMAFGATGSGKSFLMNG---NDQEIGVAPMVIQQL 200

Query: 127 FSRINDTTNDNMSYSVEVSYMEIYCERVRDLLNPKNKGNLRVREHPLLGPYVEDLSKLAV 186
           F  +   +N      V  S++EI  E++ DLLNP N+  + VR+H + G +V+ LS++  
Sbjct: 201 FQHLRQRSNK--ESMVTASFVEILDEKMTDLLNPHNR-PMAVRQHVIKGIFVDGLSEMVA 371

Query: 187 TSYNDIQDLMDSGNKARTVAATNMNETSSRSHAV 220
            +  ++  L + G +AR + AT++    +R  A 
Sbjct: 372 RTGEELSQLYEQGRRARRMGATDIKAHRARYDAA 473
>15043
          Length = 973

 Score = 94.7 bits (234), Expect = 3e-19,   Method: Compositional matrix adjust.
 Identities = 63/189 (33%), Positives = 102/189 (53%), Gaps = 1/189 (0%)
 Frame = +2

Query: 198 SGNKARTVAATNMNETSSRSHAVFNIIFTQK-RHDAETNITTEKVSKISLVDLAGSERAD 256
           +G +AR + AT++    +R+HAVF I   QK R  ++  +     + I LV+LAG E AD
Sbjct: 23  TGRRARRMGATDIKAHRARAHAVFTITVEQKERQSSKVGVR----ANIMLVELAGCEAAD 190

Query: 257 STGAKGTRLKEGANINKSLTTLGKVISALAEMDSGPXXXXXXXXTDFIPYRDSVLTWLLR 316
           +T  K     +G  +N        V+ AL +                +PYR+S++T LL+
Sbjct: 191 ATDPKILAGTQGV-VN--------VLKALGD---------SKQIGGHVPYRESLVTRLLQ 316

Query: 317 ENLGGNSRTAMVAALSPADINYDETLSTLRYADRAKQIRCNAIINEDPNNKLIRELKDEV 376
           + LGGN+ T M+  +SP D +Y  T S L+Y   AK ++ +A +N D    +I E++ ++
Sbjct: 317 DTLGGNAMTLMLVTVSPLDKSYQTTQSALQYGQFAKTVKNHARMNLDDTQDIIAEMRQDI 496

Query: 377 TRLRDLLYA 385
           +RLRD + A
Sbjct: 497 SRLRDKIAA 523
>17748
          Length = 621

 Score = 68.2 bits (165), Expect = 3e-11,   Method: Compositional matrix adjust.
 Identities = 45/126 (35%), Positives = 73/126 (57%), Gaps = 7/126 (5%)
 Frame = -3

Query: 86  FEGYNVCIFAYGQTGAGKSYTMMG------KQEKDQQGIIPQLCEDLFSRINDTTNDNMS 139
           F+GYN  + AYGQTG+GK+++M G      K +++  GIIP++ +DLF+ I +    + +
Sbjct: 373 FKGYNATVLAYGQTGSGKTFSMGGCYEASLKLDEEAMGIIPRIIKDLFNGIQE--RPDHT 200

Query: 140 YSVEVSYMEIYCERVRDLLNP-KNKGNLRVREHPLLGPYVEDLSKLAVTSYNDIQDLMDS 198
           + V VSY+EIY E + BLL P   +  L +RE       ++ L ++ V S +D  D +  
Sbjct: 199 FKVTVSYLEIYNEELLBLLCPLSQRQPLTIREELNGEIKIKGLKEVTVGSVDDTLDCLSQ 20

Query: 199 GNKART 204
           G + RT
Sbjct: 19  GAQLRT 2
>36593
          Length = 466

 Score = 50.1 bits (118), Expect = 9e-06,   Method: Composition-based stats.
 Identities = 23/47 (48%), Positives = 34/47 (72%)
 Frame = +1

Query: 311 LTWLLRENLGGNSRTAMVAALSPADINYDETLSTLRYADRAKQIRCN 357
           LT+LL+ +LGGNS+T M   +SP + N+ ETL++LR+A +  Q  CN
Sbjct: 4   LTYLLQNSLGGNSKTLMFVNVSPKEENFSETLNSLRFATKVNQ--CN 138
>38061
          Length = 206

 Score = 43.1 bits (100), Expect = 9e-04,   Method: Compositional matrix adjust.
 Identities = 19/28 (67%), Positives = 25/28 (89%)
 Frame = -3

Query: 327 MVAALSPADINYDETLSTLRYADRAKQI 354
           +VA +SPAD N +ETL+TLRYADRA++I
Sbjct: 84  LVACVSPADSNMEETLNTLRYADRARKI 1
>18965
          Length = 444

 Score = 35.8 bits (81), Expect = 0.16,   Method: Compositional matrix adjust.
 Identities = 16/45 (35%), Positives = 26/45 (57%), Gaps = 1/45 (2%)
 Frame = +2

Query: 554 VVTLEPC-EGADTYVNGKKVTEPSILRSGNRIIMGKSHVFRFNHP 597
           +VT+ P    AD YV  ++V + ++LR G  +  G+ H F+F  P
Sbjct: 2   IVTVTPTGRDADVYVEDERVVKTTMLRHGATVQFGRHHFFKFVDP 136
>08095
          Length = 935

 Score = 33.5 bits (75), Expect = 0.73,   Method: Compositional matrix adjust.
 Identities = 16/35 (45%), Positives = 19/35 (54%)
 Frame = -2

Query: 1068 SQPIVFEVFGHYQQHPFPPLCKDVLSPLRPSRRHF 1102
            S  I  E  G+YQ    PP+CK+   P RP  RHF
Sbjct: 328  STKIYLEQLGNYQ---LPPMCKNGSEPTRPRDRHF 233
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|89001109|ref|NP_034433.3| guanine nucleotide binding
protein, alpha 13 [Mus musculus]
         (377 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

11965                                                                 214   4e-56
13527                                                                 166   1e-41
20516                                                                 162   2e-40
29196                                                                 105   2e-23
08153                                                                  44   1e-04
09827                                                                  42   4e-04
18949                                                                  42   5e-04
11378                                                                  42   6e-04
34094                                                                  37   0.015
18208                                                                  34   0.12 
02085                                                                  28   7.2  
>11965
          Length = 3256

 Score =  214 bits (546), Expect = 4e-56,   Method: Compositional matrix adjust.
 Identities = 107/222 (48%), Positives = 147/222 (66%)
 Frame = +1

Query: 155 DSGIQNAYDRRREFQLGESVKYFLDNLDKLGVPDYIPSQQDILLARRPTKGIHEYDFEIK 214
           DSG+Q+ + R  E+QL +S KYFLD+LD+LG  DY+P++QDIL  R  T GI E  F  K
Sbjct: 1   DSGVQDCFSRSNEYQLNDSAKYFLDDLDRLGTKDYMPTEQDILRTRVKTTGIVEVHFSFK 180

Query: 215 NVPFKMVDVGGQRSERKRWFECFDSVTSILFLVSSSEFDQVLMEDRQTNRLTESLNIFET 274
           N+ FK+ DVGGQRSERK+W  CF+ VT+I+F V+ SE+DQVL ED  TNR+ ESL +F++
Sbjct: 181 NLNFKLFDVGGQRSERKKWIHCFEDVTAIIFCVAMSEYDQVLHEDETTNRMQESLKLFDS 360

Query: 275 IVNNRVFSNVSIILFLNKTDLLEEKVQVVSIKDYFLEFEGDPHCLRDVQKFLVECFRGKR 334
           I NN+ F++ SIILFLNK DL EEK++   +   F E+ G      +V  ++   F  K 
Sbjct: 361 ICNNKWFTDTSIILFLNKKDLFEEKIKKSPLTVCFPEYTG-KQTYEEVAAYIQAQFEAKN 537

Query: 335 RDQQQRPLYHHFTTAINTENIRLVFRDVKDTILHDNLKQLML 376
           +   Q+ +Y H T A +T NI+ VF  V D I+ +NL+   L
Sbjct: 538 K-SSQKEIYCHQTCATDTNNIQFVFDAVTDVIIANNLRGCGL 660
>13527
          Length = 1091

 Score =  166 bits (421), Expect = 1e-41,   Method: Compositional matrix adjust.
 Identities = 91/222 (40%), Positives = 129/222 (58%), Gaps = 2/222 (0%)
 Frame = -2

Query: 2    ADFLPS-RSVLSVCFPGCVLTNGEAEQQRKSKEIDKCLSREKTYVKRLVKILLLGAGESG 60
            A FL +  +  +    GC L+  E     +SK I+K L  +     + +K+LLLGAGESG
Sbjct: 1087 ASFLQACPAATTAIIMGCTLSAEERAAMERSKAIEKNLKEDGMQAAKDIKLLLLGAGESG 908

Query: 61   KSTFLKQMRIIHGQDFDQRAREEFRPTIYSNVIKGMRVLVDAREKLHIPWGDNKNQLHGD 120
            KST +KQM+IIH   F     +++RP ++SN I+ +  ++ A   L IP+GDN+ +   D
Sbjct: 907  KSTIVKQMKIIHEGGFTSEDNKQYRPVVFSNTIQSLVAIIRAMGTLSIPFGDNERE--SD 734

Query: 121  KLMAFDTRAPMAAQGMVETRVFLQ-YLPAIRALWEDSGIQNAYDRRREFQLGESVKYFLD 179
              M  D  A M      +T  F +  L A+  LW DSG+Q+ + R  E+QL +S KYFLD
Sbjct: 733  AKMVLDVIARME-----DTEPFSEELLAAMERLWMDSGVQDCFSRSNEYQLNDSAKYFLD 569

Query: 180  NLDKLGVPDYIPSQQDILLARRPTKGIHEYDFEIKNVPFKMV 221
            +LD+LG  DY+P++QDIL  R  T GI E  F  KN+ FK V
Sbjct: 568  DLDRLGTKDYMPTEQDILRTRVKTTGIVEVHFSFKNLNFKYV 443
>20516
          Length = 534

 Score =  162 bits (411), Expect = 2e-40,   Method: Compositional matrix adjust.
 Identities = 92/166 (55%), Positives = 117/166 (70%), Gaps = 4/166 (2%)
 Frame = +2

Query: 214 KNVPFKMVDV-GGQRSERKRWFECFDSVTSILFLVSSSEFDQVLMEDRQTNRLTESLNIF 272
           +N+ F + +V GGQRS+R++W++CF  +TSILFL +SSEFDQVLMEDR+TNRL ES +IF
Sbjct: 47  RNIFFLVGEVTGGQRSQRQKWYQCFVGITSILFLAASSEFDQVLMEDRKTNRLQESCDIF 226

Query: 273 ETIVNNRVFSNVSIILFLNKTDLLEEKVQVVSIKDYFLEFEG--DPH-CLRDVQKFLVEC 329
           ETI+NN+ FS VSIILFLNK DLL++K     ++  F  F G    H C + +    V  
Sbjct: 227 ETIINNKSFSGVSIILFLNKMDLLQDKN*ACQLRRLFSRFSG*SQGH*CSQSI*ASAV-* 403

Query: 330 FRGKRRDQQQRPLYHHFTTAINTENIRLVFRDVKDTILHDNLKQLM 375
           F      Q      HHFTTAI+TENI+ VF+DVKDTILHDNL+ LM
Sbjct: 404 FAPT*SKQ---TFVHHFTTAIDTENIKHVFQDVKDTILHDNLRSLM 532
>29196
          Length = 431

 Score =  105 bits (263), Expect = 2e-23,   Method: Compositional matrix adjust.
 Identities = 58/145 (40%), Positives = 87/145 (60%), Gaps = 2/145 (1%)
 Frame = -2

Query: 147 PAIRALWEDSGIQNAYDRRREFQLGESVKYFLDNLDKLGVPDYIPSQQDILLARRPTK-- 204
            A++ LW DSG+Q     R       ++   +  +  +G    I SQ +       ++  
Sbjct: 430 AAMKRLWLDSGVQEC--SRAATNTN*TIPLNISWMI*IG*ALRITSQPNRTFCAPESRPP 257

Query: 205 GIHEYDFEIKNVPFKMVDVGGQRSERKRWFECFDSVTSILFLVSSSEFDQVLMEDRQTNR 264
            +  +   +KN+ FK+ DVGGQRSERK+W  CF+ VT+I+F V+ SE+DQVL ED  TNR
Sbjct: 256 AL*RFISPLKNLNFKLFDVGGQRSERKKWIHCFEDVTAIIFCVAMSEYDQVLHEDETTNR 77

Query: 265 LTESLNIFETIVNNRVFSNVSIILF 289
           + ESL +F++I NN+ F++ SIILF
Sbjct: 76  MQESLKLFDSICNNKWFTDTSIILF 2
>08153
          Length = 1703

 Score = 43.5 bits (101), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 29/94 (30%), Positives = 45/94 (47%)
 Frame = +1

Query: 202 PTKGIHEYDFEIKNVPFKMVDVGGQRSERKRWFECFDSVTSILFLVSSSEFDQVLMEDRQ 261
           PT G +    E KN+ F + DVGGQ   R  W   F +   ++F+V S+        DR+
Sbjct: 172 PTIGFNVETVEYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSN--------DRE 327

Query: 262 TNRLTESLNIFETIVNNRVFSNVSIILFLNKTDL 295
             R+ E+      ++N     +  I++F NK DL
Sbjct: 328 --RINEAKEELARMLNEDDLRDAIILVFANKQDL 423
>09827
          Length = 1201

 Score = 42.0 bits (97), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 31/94 (32%), Positives = 47/94 (50%)
 Frame = -3

Query: 202  PTKGIHEYDFEIKNVPFKMVDVGGQRSERKRWFECFDSVTSILFLVSSSEFDQVLMEDRQ 261
            PT G +    E KN+ F + DVGGQ   R  W   F +   ++F+V S++ ++V  E R+
Sbjct: 1025 PTIGFNVETVEYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDKERV-QEARE 849

Query: 262  TNRLTESLNIFETIVNNRVFSNVSIILFLNKTDL 295
               LT  LN  E         +  +++F NK DL
Sbjct: 848  --ELTRMLNEDE-------LRDAVLLVFANKQDL 774
>18949
          Length = 414

 Score = 42.0 bits (97), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 22/94 (23%), Positives = 45/94 (47%)
 Frame = +3

Query: 201 RPTKGIHEYDFEIKNVPFKMVDVGGQRSERKRWFECFDSVTSILFLVSSSEFDQVLMEDR 260
           RPT      +  +  + F   D+GG R  R+ W + F +V  I+F+V   +         
Sbjct: 12  RPTGLPTSEELSMGGMTFTTFDLGGHRQARRVWKDYFPAVDGIVFIVDVHD--------- 164

Query: 261 QTNRLTESLNIFETIVNNRVFSNVSIILFLNKTD 294
            T R+TE+    ++++ +   +++ +++  NK D
Sbjct: 165 -TERITEAKAELDSLLRDDQIADIPVLVLGNKMD 263
>11378
          Length = 1688

 Score = 41.6 bits (96), Expect = 6e-04,   Method: Compositional matrix adjust.
 Identities = 32/124 (25%), Positives = 56/124 (45%), Gaps = 1/124 (0%)
 Frame = +3

Query: 172 ESVKYFLDNLDKLGVPDYIPSQQDILLARR-PTKGIHEYDFEIKNVPFKMVDVGGQRSER 230
           +S K     LD  G    +   +D  +A+  PT      +  +  + F   D+GG R  R
Sbjct: 318 KSGKLVFLGLDNAGKTTLLHMLKDDKMAQHVPTLHPTSEELSMGGMRFTTFDLGGHRQAR 497

Query: 231 KRWFECFDSVTSILFLVSSSEFDQVLMEDRQTNRLTESLNIFETIVNNRVFSNVSIILFL 290
           + W + F +V  I+FLV         + DR+  RL E+    ++++ +   +N  I++  
Sbjct: 498 RVWKDYFPAVDGIVFLVD--------VHDRE--RLVEAKAELDSLMTDEQVANAPILVLG 647

Query: 291 NKTD 294
           NK D
Sbjct: 648 NKID 659
>34094
          Length = 452

 Score = 36.6 bits (83), Expect = 0.015,   Method: Compositional matrix adjust.
 Identities = 15/43 (34%), Positives = 25/43 (58%)
 Frame = +1

Query: 69  RIIHGQDFDQRAREEFRPTIYSNVIKGMRVLVDAREKLHIPWG 111
           RIIH + + Q    +++P +YSN I+ M  +V A   L + +G
Sbjct: 103 RIIHEKGYSQEECLQYKPVVYSNAIQSMIAIVRAMNLLSVEFG 231
>18208
          Length = 458

 Score = 33.9 bits (76), Expect = 0.12,   Method: Compositional matrix adjust.
 Identities = 14/50 (28%), Positives = 27/50 (54%)
 Frame = -1

Query: 202 PTKGIHEYDFEIKNVPFKMVDVGGQRSERKRWFECFDSVTSILFLVSSSE 251
           PT+G +    + K     + D+GGQR  R  W   F++   +++++ SS+
Sbjct: 212 PTQGFNIKSVQSKGFKLNVWDIGGQRRIRPYWKNYFENTDLLIYVIDSSD 63
>02085
          Length = 1060

 Score = 27.7 bits (60), Expect = 7.2,   Method: Compositional matrix adjust.
 Identities = 12/42 (28%), Positives = 21/42 (50%)
 Frame = +2

Query: 16  PGCVLTNGEAEQQRKSKEIDKCLSREKTYVKRLVKILLLGAG 57
           P C ++  +  Q  KSK + K       Y + ++K+ L+G G
Sbjct: 347 PNCFISKYDCTQ*NKSKCVAKVFQYSANYPRLIIKVPLIGQG 472
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|157951706|ref|NP_067370.3| hypoxia up-regulated 1
[Mus musculus]
         (999 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

03996                                                                 216   5e-56
20979                                                                 149   8e-56
12271                                                                 127   1e-53
13300                                                                 159   6e-39
27378                                                                 106   4e-23
20381                                                                 102   1e-21
37715                                                                  77   5e-14
21024                                                                  69   1e-11
08260                                                                  57   3e-08
31218                                                                  47   3e-05
30255                                                                  43   7e-04
09881                                                                  41   0.002
>03996
          Length = 1105

 Score =  216 bits (549), Expect = 5e-56,   Method: Compositional matrix adjust.
 Identities = 114/240 (47%), Positives = 154/240 (64%), Gaps = 4/240 (1%)
 Frame = -2

Query: 350  ELCADLFDRVPGPVQQALQSAEMSLDQIEQVILVGGATRVPKVQEVLLKAVGKEELGKNI 409
            EL  DL  RV  P++ AL+ +E+++ +I ++IL+GG +RVP+VQE LLK  GK +LGK+I
Sbjct: 1056 ELIKDLLARVTKPMEDALKVSEITMPEITEIILMGGGSRVPRVQEELLKFSGKSDLGKSI 877

Query: 410  NADEXXXXXXXXXXXXLSKAFKVKPFVVRDAVIYPILVEFTREVEEEPGLRSLKHNKRVL 469
            N DE            L K FKVK F VRDA IYPI VEF ++  EE    S +  KR L
Sbjct: 876  NTDEAAALGAVYQAAYLGKGFKVKTFHVRDANIYPINVEFEKQKSEEDSATSARTIKRTL 697

Query: 470  FSRMGPYPQRKVITFNRYSHDFNFHINYGDLGFLGPEDLRVFGSQNLTTVKLKGVGESFK 529
            F RM PYPQRKV+TFN++  DFNF + YGDL F+  E+ +   ++ L+ V L+GV   + 
Sbjct: 696  FGRMNPYPQRKVMTFNKHFKDFNFEVRYGDLDFIPEEEQKSLSARLLSNVSLEGVESXYG 517

Query: 530  KY-PDYESKGIKAHFNLDESGVLSLDRVESVFETLV---EDSPEEESTLTKLGNTISSLF 585
            K   + E KG+KAHF +DESG+L L++VESVFE       +  E+EST +K+GN    LF
Sbjct: 516  KLGEEAEYKGVKAHFRMDESGILHLEKVESVFEKQQAGEAEVAEDESTWSKIGNAFGGLF 337
>20979
          Length = 976

 Score =  149 bits (377), Expect(2) = 8e-56,   Method: Compositional matrix adjust.
 Identities = 77/151 (50%), Positives = 107/151 (70%)
 Frame = +1

Query: 284 AKLFNEQRKGQKAKDVRENPRAMAKLLREANRLKTVLSANADHMAQIEGLMDDVDFKAKV 343
           AK+FN Q+K  ++  + +NPRAMAKLL+EA R+K VLSAN+DH AQ+EGL++  DF AKV
Sbjct: 106 AKVFNGQKK--RSFKLEDNPRAMAKLLKEAERVKKVLSANSDHKAQVEGLVEGEDFAAKV 279

Query: 344 TRVEFEELCADLFDRVPGPVQQALQSAEMSLDQIEQVILVGGATRVPKVQEVLLKAVGKE 403
           +R ++ EL  DL  RV  P++ AL+ +E+++ +I ++IL+GG +RVP+VQE LLK  GK 
Sbjct: 280 SREDYLELIKDLLARVTKPMEDALKVSEITMPEITEIILMGGGSRVPRVQEELLKFSGKS 459

Query: 404 ELGKNINADEXXXXXXXXXXXXLSKAFKVKP 434
           +LGK+IN DE            L K FKVKP
Sbjct: 460 DLGKSINTDEAAALGAVYQAAYLGKGFKVKP 552

 Score = 87.4 bits (215), Expect(2) = 8e-56,   Method: Compositional matrix adjust.
 Identities = 42/73 (57%), Positives = 51/73 (69%)
 Frame = +3

Query: 435 FVVRDAVIYPILVEFTREVEEEPGLRSLKHNKRVLFSRMGPYPQRKVITFNRYSHDFNFH 494
           F VRDA IYPI VEF ++  EE    S +  KR LF RM PYPQRKV+TFN++  DFNF 
Sbjct: 552 FHVRDANIYPINVEFEKQKSEEDSPTSARTIKRTLFGRMNPYPQRKVMTFNKHFKDFNFE 731

Query: 495 INYGDLGFLGPED 507
           + YGDL F+ PE+
Sbjct: 732 VRYGDLDFI-PEE 767
>12271
          Length = 1762

 Score =  127 bits (319), Expect(2) = 1e-53,   Method: Compositional matrix adjust.
 Identities = 62/143 (43%), Positives = 90/143 (62%)
 Frame = +2

Query: 338 DFKAKVTRVEFEELCADLFDRVPGPVQQALQSAEMSLDQIEQVILVGGATRVPKVQEVLL 397
           DF  KVTR ++  L  DL DRV  PVQQ L +++++  +I ++IL+GG +R+PK+ E+LL
Sbjct: 41  DFSCKVTRDKYLHLIQDLLDRVTLPVQQVLTASQITWAEITEIILMGGGSRLPKIHEILL 220

Query: 398 KAVGKEELGKNINADEXXXXXXXXXXXXLSKAFKVKPFVVRDAVIYPILVEFTREVEEEP 457
              GK+ELGK++N DE            L+K FKVK F VRDA ++PI VEF ++   E 
Sbjct: 221 DYSGKKELGKSLNTDEAGALGAVYQAAYLAKGFKVKTFHVRDANLFPINVEFAKQTTNEE 400

Query: 458 GLRSLKHNKRVLFSRMGPYPQRK 480
           G   +K  +R LF R   +P+R+
Sbjct: 401 GSEEVKVIQRTLFGRSHYFPRRR 469

 Score =  102 bits (254), Expect(2) = 1e-53,   Method: Compositional matrix adjust.
 Identities = 63/150 (42%), Positives = 87/150 (58%), Gaps = 7/150 (4%)
 Frame = +1

Query: 477 PQRKVITFN-RYSHDFNFHINYGDLGFLGPEDLRVFGSQNLTTVKLKGVGESF-KKYPDY 534
           PQ+KV+TFN  Y  DF F + YGDL FL  E+ ++  +  L+ V LKGV +++ K+    
Sbjct: 457 PQKKVMTFNTHYVKDFTFDLRYGDLDFLDDEENKLLSTSVLSRVGLKGVDKAYAKRSASA 636

Query: 535 ESKGIKAHFNLDESGVLSLDRVESVFETLVEDSPE--EESTLTKLGNTISSLFGGGTSSD 592
             KG+KAHF +D SG+L LD+ E VFE   E  PE  ++ST +KLG+ I S+FGG     
Sbjct: 637 TYKGVKAHFRMDSSGLLHLDKAECVFE---EGLPEQTDDSTWSKLGSAIGSMFGG----- 792

Query: 593 AKENGTDAVQEEEESPAE---GSKDEPAEQ 619
                     EEE++  +     KDEPA Q
Sbjct: 793 ----------EEEDNTQQTDKTGKDEPATQ 852

 Score = 67.0 bits (162), Expect(2) = 4e-19,   Method: Compositional matrix adjust.
 Identities = 43/102 (42%), Positives = 62/102 (60%), Gaps = 2/102 (1%)
 Frame = +2

Query: 822  LSALDNLLNHSSIFLKGARLIPEMDQ--VFTEVEMTTLEKVINDTWAWKNATLAEQAKLP 879
            LS LD  L  S+ FL+ AR      Q  +++E ++TTL+K+IN+T  WK     +Q K  
Sbjct: 1346 LSNLDRHLETSASFLRQARDDNARSQSPIYSESDLTTLDKLINETSKWKEDGERKQGKRG 1525

Query: 880  ATEKPVLLSKDIEAKMMALDREVQYLLNKAKFTKPRPRPKDK 921
            +   P LL +DI+AK+ AL+REV++L NK K T  +  PK K
Sbjct: 1526 SNXDPSLLVQDIQAKVKALEREVKFLKNKKK-TSSKQAPKAK 1648

 Score = 46.6 bits (109), Expect(2) = 4e-19,   Method: Compositional matrix adjust.
 Identities = 27/72 (37%), Positives = 41/72 (56%)
 Frame = +1

Query: 718  RSVQKLEELTLRDLEKQEREKAANSLEAFIFETQDKLYQPEYQEVSTEEQREEISGKLSA 777
            +S ++L +   RD EK   +KA N +E+FI   QDK+ +  Y   ST+E+R  I  +LS 
Sbjct: 1036 QSKKRLTDWRKRDEEKAAVQKARNEVESFIITAQDKMSEETYLASSTDEERAXILDQLSQ 1215

Query: 778  TSTWLEDEGFGA 789
             S WL ++   A
Sbjct: 1216 ASDWLYEQSHQA 1251
>13300
          Length = 453

 Score =  159 bits (401), Expect = 6e-39,   Method: Compositional matrix adjust.
 Identities = 82/152 (53%), Positives = 104/152 (68%), Gaps = 3/152 (1%)
 Frame = +3

Query: 184 ERRAVLQAARMAGLKVLQLINDNTATALSYGVFRRKDINSTAQNVMFYDMGSGSTVCTIV 243
           ERRA++ AA   G+ VLQL+ D+ A AL+YGVFRRK+ N+TAQ  MFYDMG+ STV T+V
Sbjct: 3   ERRAIMTAADXVGINVLQLMTDSAAVALNYGVFRRKNFNTTAQYYMFYDMGATSTVATVV 182

Query: 244 TYQTVKTKEAG---MQPQLQIRGVGFDXXXXXXXXXXXXXXXXAKLFNEQRKGQKAKDVR 300
           +YQ VK KE       PQL I+GVGFD                AK+FN Q+K  ++  + 
Sbjct: 183 SYQVVKVKEGTRVESNPQLTIKGVGFDRTLGGLEMTLRLRDHLAKVFNGQKK--RSFKLE 356

Query: 301 ENPRAMAKLLREANRLKTVLSANADHMAQIEG 332
           +NPRAMAKLL+EA R+K VLSAN+DH AQ+EG
Sbjct: 357 DNPRAMAKLLKEAERVKKVLSANSDHKAQVEG 452
>27378
          Length = 410

 Score =  106 bits (265), Expect = 4e-23,   Method: Compositional matrix adjust.
 Identities = 51/117 (43%), Positives = 75/117 (64%)
 Frame = -1

Query: 297 KDVRENPRAMAKLLREANRLKTVLSANADHMAQIEGLMDDVDFKAKVTRVEFEELCADLF 356
           KD+R NPRA+ +L   A R K  LS++ +   +++ L +  DF  K++R  FEELCADLF
Sbjct: 389 KDLRSNPRALRRLRTAAERAKRTLSSSTEATIEVDALFEGHDFYTKISRARFEELCADLF 210

Query: 357 DRVPGPVQQALQSAEMSLDQIEQVILVGGATRVPKVQEVLLKAVGKEELGKNINADE 413
            +   PV++AL  A+M    I  ++LVGG+TR+PKVQ +L +  G + L  +IN DE
Sbjct: 209 RQTLAPVEKALNDAKMDKQMIHDIVLVGGSTRIPKVQNLLQQFFGGKSLNLSINPDE 39
>20381
          Length = 456

 Score =  102 bits (253), Expect = 1e-21,   Method: Compositional matrix adjust.
 Identities = 58/130 (44%), Positives = 84/130 (64%), Gaps = 1/130 (0%)
 Frame = +2

Query: 796 DKLAELRKLCQGLFFRVEERRKWPERLSALDNLLNHSSIFLKGAR-LIPEMDQVFTEVEM 854
           +KL E + L + +  RV E+ + P+ L+AL + LN +  FLK    +    D +FT VE+
Sbjct: 11  NKLKEAKDLMKNIQLRVYEKEERPKALAALKHHLNATDHFLKTVHNMTDPQDPMFTPVEL 190

Query: 855 TTLEKVINDTWAWKNATLAEQAKLPATEKPVLLSKDIEAKMMALDREVQYLLNKAKFTKP 914
            TLEK+IN+T AW++  LAEQAK+P  + P LL   I +K+ AL+RE++YL+NKAK    
Sbjct: 191 ATLEKLINETTAWRDEALAEQAKVPDHQNPTLLVGAIGSKIYALEREMKYLINKAK--NY 364

Query: 915 RPRPKDKNGT 924
           RP+PK  N T
Sbjct: 365 RPKPKTDNST 394
>37715
          Length = 468

 Score = 76.6 bits (187), Expect = 5e-14,   Method: Compositional matrix adjust.
 Identities = 35/75 (46%), Positives = 54/75 (72%)
 Frame = -2

Query: 144 FSPEEVLGMVLNYSRSLAEDFAEQPIKDAVITVPAFFNQAERRAVLQAARMAGLKVLQLI 203
           F+PEE+  MVL   R +AE +  + I +AV+TVPA+FN A+R+A   A  +AGL V+++I
Sbjct: 392 FAPEEISAMVLGKMRDIAEAYLGKKIDNAVVTVPAYFNDAQRQATKDAGTIAGLNVMRII 213

Query: 204 NDNTATALSYGVFRR 218
           N+ TA A++YG+ +R
Sbjct: 212 NEPTAAAIAYGLDKR 168
>21024
          Length = 3220

 Score = 68.6 bits (166), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 47/166 (28%), Positives = 85/166 (51%), Gaps = 1/166 (0%)
 Frame = +3

Query: 36  MSVDLGSESMKVAIVKPGVPMEIVLNKESRRKTPVTVTL-KENERFLGDSAAGMAIKNPK 94
           + +DLG+ +  VA+++ G   +++ N E  R TP  +   K+ ER  G  A   A+ N +
Sbjct: 255 IGIDLGTTNSCVALME-GKQAKVLENSEGSRTTPSVIAFTKDGERISGMPAKRQAVTNAE 431

Query: 95  ATLRYFQHLLGKQADNPHVALYRSRFPEHELIVDPQRQTVRFQISPQLQFSPEEVLGMVL 154
            TL   + L+G++ ++P V            IV         +   ++ +SP +V   VL
Sbjct: 432 NTLSATKRLIGRRFEDPEVQKDMKNVSYK--IVKASNGDAWVEAQGKM-YSPSQVGAFVL 602

Query: 155 NYSRSLAEDFAEQPIKDAVITVPAFFNQAERRAVLQAARMAGLKVL 200
              +  AE +    + +AV+TVPA+FN ++R+A   A +++GLK +
Sbjct: 603 MKMKETAESYLGSKVNNAVVTVPAYFNDSQRQATKDAGQISGLKCV 740

 Score = 58.2 bits (139), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 32/72 (44%), Positives = 44/72 (61%)
 Frame = +1

Query: 342  KVTRVEFEELCADLFDRVPGPVQQALQSAEMSLDQIEQVILVGGATRVPKVQEVLLKAVG 401
            K++R +FE L   L  R  GP Q+ALQ AE+    I +VILVGG +R+PKVQ  +    G
Sbjct: 1123 KLSRSKFESLVESLVKRTVGPCQKALQDAEVKKSDIGEVILVGGMSRMPKVQSTVQDLFG 1302

Query: 402  KEELGKNINADE 413
            +    K++N DE
Sbjct: 1303 RTP-SKSVNPDE 1335
>08260
          Length = 441

 Score = 57.4 bits (137), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 28/54 (51%), Positives = 37/54 (68%), Gaps = 3/54 (5%)
 Frame = -3

Query: 535 ESKGIKAHFNLDESGVLSLDRVESVFE---TLVEDSPEEESTLTKLGNTISSLF 585
           E KG+KAHF +DESG+L L++VESVFE       +  E+EST +K+GN    LF
Sbjct: 415 EYKGVKAHFRMDESGILHLEKVESVFEKQQAGEAEVAEDESTWSKIGNAFGGLF 254
>31218
          Length = 322

 Score = 47.4 bits (111), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 27/79 (34%), Positives = 44/79 (55%)
 Frame = +2

Query: 292 KGQKAKDVRENPRAMAKLLREANRLKTVLSANADHMAQIEGLMDDVDFKAKVTRVEFEEL 351
           K +  +DVR + RAM++L R A + K  LS+       ++G+  D+     +TR +FEEL
Sbjct: 65  KQKTGRDVRHDTRAMSRLRRSAEKAKRALSSQHSTKVDLDGVTSDL-ADLTLTRAKFEEL 241

Query: 352 CADLFDRVPGPVQQALQSA 370
             DLF      V++AL+ +
Sbjct: 242 NTDLFRSTLTTVKRALEDS 298
>30255
          Length = 1761

 Score = 42.7 bits (99), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 31/116 (26%), Positives = 54/116 (46%), Gaps = 2/116 (1%)
 Frame = -1

Query: 377  IEQVILVGGATRVPKVQEVLLKAVGKEELGKNINADEXXXXXXXXXXXXL--SKAFKVKP 434
            I +++LVGG+TR+PK+Q++L      +EL K+IN DE            L   K+ +V+ 
Sbjct: 1635 IHEIVLVGGSTRIPKIQKLLQDFFNGKELCKSINPDEAVAYGACVQAAILHGDKSEEVQD 1456

Query: 435  FVVRDAVIYPILVEFTREVEEEPGLRSLKHNKRVLFSRMGPYPQRKVITFNRYSHD 490
             ++ D      +   +  +E   G+ +       L  R    P ++  TF  YS +
Sbjct: 1455 LLLLD------VAPLSMGIETAGGVMT------ALIKRNTTIPTKQTQTFTTYSDN 1324
>09881
          Length = 600

 Score = 41.2 bits (95), Expect = 0.002,   Method: Composition-based stats.
 Identities = 23/45 (51%), Positives = 32/45 (71%)
 Frame = +2

Query: 169 IKDAVITVPAFFNQAERRAVLQAARMAGLKVLQLINDNTATALSY 213
           I+DAV+ VP+ F+  +R A   AA  AG KVL+LIN+ +A AL+Y
Sbjct: 11  IQDAVLAVPSDFSDKQRAAASAAASKAGFKVLRLINECSAAALAY 145
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|215983062|ref|NP_065603.2| EH-domain containing 3
[Mus musculus]
         (535 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

28292                                                                 214   5e-56
19303                                                                 149   8e-50
01130                                                                  74   2e-13
01021                                                                  39   0.005
33913                                                                  32   0.65 
20290                                                                  31   1.6  
14189                                                                  28   8.5  
18248                                                                  28   8.8  
>28292
          Length = 1324

 Score =  214 bits (546), Expect = 5e-56,   Method: Compositional matrix adjust.
 Identities = 114/274 (41%), Positives = 158/274 (57%), Gaps = 2/274 (0%)
 Frame = -3

Query: 37   EEYYRFHEFHSPALEDADFDNKPMVLLVGQYSTGKTTFIRYLL--EQDFPGMRIGPEPTT 94
            E+ YRF + +  A+ + +   KPM+L +G +STGK+T I Y+L  EQ    +  G EPTT
Sbjct: 1169 EQAYRFADLNRDAISEGEMLAKPMILFLGPWSTGKSTMINYILKNEQANWKLHTGAEPTT 990

Query: 95   DSFIAVMQGDVEGIIPGNALVVDPKKPFRKLNAFGNAFLNRFVCAQLPNAVLESISVIDT 154
              F  V  G    ++ G  LV D  K +  L  FG  FL RF   +LP  +L+ ++++DT
Sbjct: 989  SDFTMVTYGITARMVKGIQLVSDKTKHYTPLQKFGLNFLERFQGMELPAPLLKQVTLVDT 810

Query: 155  PGILSGEKQRISRGYDFAAVLEWFAERVDRIILLFDAHKLDISDEFSEVIKALKNHEDKM 214
            PGI+  +KQ+  RGY F  V +WF +R   I L+FD  KLDI  E   + + LK HE K+
Sbjct: 809  PGIIENKKQQ-ERGYPFNDVCQWFIDRAQLIFLVFDPSKLDIGSELEMLFRQLKGHEAKL 633

Query: 215  RVVLNKADQIETQQLMRVYGALMWSLGKIVNTPEVIRVYIGSFWSHPLLIPDNRKLFEAE 274
            R++LNKAD + TQ+LMRVYGAL WSL  ++N  E  RVY+GS WS          LFE E
Sbjct: 632  RLILNKADTVTTQELMRVYGALFWSLAPLINLVEPPRVYVGSMWSQSYQPTTMHTLFEEE 453

Query: 275  EQDLFRDIQSLPRNAALRKLNDLIKRARLAKVHA 308
            E  L  D+Q + R     K+    + A L ++HA
Sbjct: 452  ETSLSMDLQQVIRYQLEYKIAATRRHAFLVRLHA 351
>19303
          Length = 676

 Score =  149 bits (377), Expect(2) = 8e-50,   Method: Compositional matrix adjust.
 Identities = 67/94 (71%), Positives = 85/94 (90%)
 Frame = -1

Query: 438 EWVVARDKPMYDEIFYTLSPVDGKITGANAKKEMVRSKLPNSVLGKIWKLADIDKDGMLD 497
           EWVV+R+K  YD+ F  L+P++GK++GA AK EMV+SKLPNSVL K+WKLAD+DKDGMLD
Sbjct: 418 EWVVSREKYEYDDSFSKLNPINGKVSGAAAKSEMVKSKLPNSVLSKVWKLADVDKDGMLD 239

Query: 498 DEEFALANHLIKVKLEGHELPSELPAHLLPPSKR 531
            +E+ALANHLIK+KLEGH+LPS+LP+HL+PPSKR
Sbjct: 238 ADEWALANHLIKIKLEGHDLPSDLPSHLVPPSKR 137

 Score = 66.2 bits (160), Expect(2) = 8e-50,   Method: Compositional matrix adjust.
 Identities = 34/63 (53%), Positives = 44/63 (69%), Gaps = 2/63 (3%)
 Frame = -2

Query: 356 LKRMQDQLQAQDFSKFQPLKSKLLEVVDDMLAHDIAQLMVLV--RQEETQRPVQMVKGGA 413
           LKRMQ+QL   DF+KF  +K KLLE VD+MLA+DIA+LM ++    E+       V+GGA
Sbjct: 672 LKRMQEQLAFHDFTKFHAIKPKLLETVDNMLANDIARLMQMIPLEDEDQSNGQAAVQGGA 493

Query: 414 FEG 416
           FEG
Sbjct: 492 FEG 484
>01130
          Length = 1032

 Score = 73.9 bits (180), Expect = 2e-13,   Method: Compositional matrix adjust.
 Identities = 38/96 (39%), Positives = 54/96 (56%), Gaps = 2/96 (2%)
 Frame = +3

Query: 435 DDAEWVVARD--KPMYDEIFYTLSPVDGKITGANAKKEMVRSKLPNSVLGKIWKLADIDK 492
           D  EW V  D  + +Y+ +FY+  PVDG I G   +   ++S L   VL +IW LAD+  
Sbjct: 198 DGTEWPVVSDEERQLYELLFYSQGPVDGYILGEGVRDLFLKSGLSLRVLSQIWNLADVSN 377

Query: 493 DGMLDDEEFALANHLIKVKLEGHELPSELPAHLLPP 528
           D +L+  EF+L  HLI+   +G + P  LP  L PP
Sbjct: 378 DNVLNVHEFSLVMHLIRGLHKGLKAPPTLPRKLTPP 485

 Score = 48.1 bits (113), Expect = 9e-06,   Method: Compositional matrix adjust.
 Identities = 31/96 (32%), Positives = 50/96 (52%), Gaps = 8/96 (8%)
 Frame = +3

Query: 444 DKPMYDEIFYTLSPVDGK--ITGANAKKEMVRSKLPNSVLGKIWKLADIDKDGMLDDEEF 501
           ++  Y ++F  L  V GK  + G   +     S+L + VL  +W L+D+ +DG LD +EF
Sbjct: 525 EREAYIKLFRALD-VQGKGFLDGDCCRHVFEASELTSDVLSDVWNLSDVTRDGKLDVDEF 701

Query: 502 ALANHLIKVKLEGHELP------SELPAHLLPPSKR 531
            +A HL++    G+ L       +ELP  + P S R
Sbjct: 702 CVACHLLRFVKAGNSLSGPVDVFTELPDKVAPQSLR 809
>01021
          Length = 2238

 Score = 38.9 bits (89), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 38/153 (24%), Positives = 67/153 (43%), Gaps = 3/153 (1%)
 Frame = +2

Query: 74  FIRYLLEQDFPGMRIGPEPTTDSFIAVMQGDVEGIIPGNA-LVVDPK-KPFRKLNAFGNA 131
           F RY+ E      + G    T  F  V  G     + GNA L + P  +P R++    + 
Sbjct: 176 FERYVEEH---VQKTGVAIETQGFTFVTSGRKRESLTGNATLHLYPHFEPLRQIEGVLD- 343

Query: 132 FLNRFVCAQLPNAVLESISVIDTPGILSGEKQRISRGYDFAAVLEWFAERVDRIILLFDA 191
           +LN  +           ++ +DTPG++ G+   +   +D    + W  +  D I + FD 
Sbjct: 344 YLNTEISTS-KQKKFSLVTFVDTPGLVDGD---MKYPFDVNKSILWLGDLADLIFIFFDP 511

Query: 192 HKLDISDEFSEVIKAL-KNHEDKMRVVLNKADQ 223
               +      +++ L + H D+MR  L+KAD+
Sbjct: 512 IGQALCKRTLNLVEKLNEKHADRMRFYLSKADE 610
>33913
          Length = 1202

 Score = 32.0 bits (71), Expect = 0.65,   Method: Compositional matrix adjust.
 Identities = 21/77 (27%), Positives = 40/77 (51%)
 Frame = +1

Query: 267 NRKLFEAEEQDLFRDIQSLPRNAALRKLNDLIKRARLAKVHAYIISSLKKEMPSVFGKDT 326
           NR L E   QDL R I +LPR+AA +   D ++      V     + L+K + + +G   
Sbjct: 715 NRDLAELPTQDLIRAISTLPRDAAWKA--DHLQTIERLLVKRLYNTPLEKCLQACYGFYN 888

Query: 327 KKKELVNNLAEIYGRIE 343
           ++  LV  +++++  ++
Sbjct: 889 QEHYLVPFVSQMFSVVD 939
>20290
          Length = 1550

 Score = 30.8 bits (68), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 16/51 (31%), Positives = 27/51 (52%), Gaps = 7/51 (13%)
 Frame = +1

Query: 49  ALEDADFDNKPMVLLVGQYSTGKTTFIRYLL-------EQDFPGMRIGPEP 92
            ++   F +  +++L+G+  TGKTTFIR L        E + P + I  +P
Sbjct: 751 TVQQGHFSDSEILVLLGENGTGKTTFIRMLAGNLQPDGEVELPMLNISYKP 903
>14189
          Length = 430

 Score = 28.1 bits (61), Expect = 8.5,   Method: Composition-based stats.
 Identities = 11/34 (32%), Positives = 23/34 (67%)
 Frame = +2

Query: 487 LADIDKDGMLDDEEFALANHLIKVKLEGHELPSE 520
           +A++ +D ++DDEE     +L+ ++ EG + P+E
Sbjct: 17  IAEVPEDALIDDEEIVDEENLLAMEEEGEQQPAE 118
>18248
          Length = 466

 Score = 28.1 bits (61), Expect = 8.8,   Method: Composition-based stats.
 Identities = 14/40 (35%), Positives = 24/40 (60%)
 Frame = +3

Query: 53  ADFDNKPMVLLVGQYSTGKTTFIRYLLEQDFPGMRIGPEP 92
            +F +  +++++G+  TGKTTFI+ L  +  P    GP P
Sbjct: 84  GEFTDSEIIVMLGENGTGKTTFIKMLAGKLEPD-EGGPTP 200
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|9055370|ref|NP_061269.1| eukaryotic translation
initiation factor 3, subunit I [Mus musculus]
         (325 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

31864                                                                 214   5e-56
02147                                                                 100   1e-21
01327                                                                  64   1e-10
03156                                                                  63   1e-10
12574                                                                  55   3e-08
27465                                                                  55   4e-08
30256                                                                  50   1e-06
02090                                                                  49   2e-06
19949                                                                  47   1e-05
17602                                                                  46   3e-05
03395                                                                  42   4e-04
00561                                                                  41   6e-04
17266                                                                  37   0.009
12960                                                                  37   0.010
04524                                                                  37   0.015
01805                                                                  36   0.020
04088                                                                  36   0.024
15337                                                                  35   0.031
17598                                                                  35   0.039
17298                                                                  35   0.046
21921                                                                  35   0.057
36111                                                                  34   0.10 
35607                                                                  33   0.11 
14555                                                                  33   0.14 
15780                                                                  33   0.22 
18981                                                                  32   0.34 
19498                                                                  32   0.48 
19863                                                                  31   0.58 
13278                                                                  31   0.64 
15118                                                                  31   0.78 
12806                                                                  30   0.91 
13335                                                                  30   1.1  
03464                                                                  30   1.2  
21105                                                                  30   1.3  
19140                                                                  30   1.4  
10162                                                                  30   1.4  
31384                                                                  30   1.5  
11493                                                                  30   1.7  
27525                                                                  29   2.2  
36348                                                                  29   2.4  
15972                                                                  29   2.5  
01249                                                                  29   2.6  
14500                                                                  28   3.4  
02960                                                                  28   3.5  
38177                                                                  28   4.1  
30297                                                                  28   4.1  
18320                                                                  28   4.4  
10824                                                                  28   5.0  
01462                                                                  28   5.7  
27806                                                                  27   8.5  
03387                                                                  27   9.7  
>31864
          Length = 545

 Score =  214 bits (544), Expect = 5e-56,   Method: Compositional matrix adjust.
 Identities = 103/149 (69%), Positives = 125/149 (83%)
 Frame = +2

Query: 176 KSGEVLVNVKEHSRQINDIQLSRDMTMFVTASKDNTAKLFDSTTLEHQKTFRTERPVNSA 235
           K  +V+ +  +H+  IND+QLS+D TMFVTASKD TAKLFDS +L   KT++TERPVNSA
Sbjct: 14  KGQKVVDSGVDHTGGINDMQLSKDGTMFVTASKDTTAKLFDSESLMCLKTYKTERPVNSA 193

Query: 236 ALSPNYDHVVLGGGQEAMDVTTTSTRIGKFEARFFHLAFEEEFGRVKGHFGPINSVAFHP 295
           A+SP  DHVVLGGGQ+AM+VTTTST+ GKF++RFFHL +EEEF R+KGHFGPINS+AFHP
Sbjct: 194 AISPILDHVVLGGGQDAMEVTTTSTKAGKFDSRFFHLIYEEEFARLKGHFGPINSLAFHP 373

Query: 296 DGKSYSSGGEDGYVRIHYFDPQYFEFEFE 324
           DGKSY+SGGEDG+VR+  FD  YFE  FE
Sbjct: 374 DGKSYASGGEDGFVRVKSFDSTYFENIFE 460
>02147
          Length = 1547

 Score =  100 bits (248), Expect = 1e-21,   Method: Compositional matrix adjust.
 Identities = 69/271 (25%), Positives = 125/271 (46%)
 Frame = +2

Query: 41  NGERLGTYMGHTGAVWCVDADWDTKHVLTGSADNSCRLWDCETGKQLALLKTNSAVRTCG 100
            G+ +GT+ GH GAVW    + +     TG+AD S ++WD E G++L        V++  
Sbjct: 140 TGDWIGTFEGHKGAVWGATLNREATRAATGAADFSAKIWDAEKGEELQTFSHKHIVKSVD 319

Query: 101 FDFGGNIIMFSTDKQMGYQCFVSFFDLRDPSQIDSNEPYMKIPCNDSKITSAVWGPLGEC 160
           F   G  ++  +++++     +  FDL     ++++        + S I  A++   G+ 
Sbjct: 320 FSHDGTALLTGSNEKL-----LKVFDL-----VNTDAEPKSFAGHTSNIKGALFLSDGKR 469

Query: 161 VIAGHESGELNQYSAKSGEVLVNVKEHSRQINDIQLSRDMTMFVTASKDNTAKLFDSTTL 220
           +I+  +   +  +S ++ + +  +   +   + + LS D    +     N A  + + TL
Sbjct: 470 IISASDDKTVRLWSLETCQEVQQLTFDTPPTS-LTLSPDKNTIIVTHSQNIA-FYQADTL 643

Query: 221 EHQKTFRTERPVNSAALSPNYDHVVLGGGQEAMDVTTTSTRIGKFEARFFHLAFEEEFGR 280
              K F  E P++SA+L  +    V GG                F+   F     +E   
Sbjct: 644 REMKKFEAEAPISSASLHQSERFFVAGGED--------------FKMYKFDYETGKEIES 781

Query: 281 VKGHFGPINSVAFHPDGKSYSSGGEDGYVRI 311
            KGHFGP++ V F PDG+ Y+SG EDG +R+
Sbjct: 782 FKGHFGPVHCVRFSPDGELYASGSEDGTLRL 874

 Score = 45.1 bits (105), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 57/301 (18%), Positives = 112/301 (37%), Gaps = 44/301 (14%)
 Frame = +2

Query: 6   LQGHERSITQIKYNREGDLLFTVAKDPIVNVWYSVNGERLGT------------------ 47
            +GH+ ++     NRE     T A D    +W +  GE L T                  
Sbjct: 161 FEGHKGAVWGATLNREATRAATGAADFSAKIWDAEKGEELQTFSHKHIVKSVDFSHDGTA 340

Query: 48  ------------------------YMGHTGAVWCVDADWDTKHVLTGSADNSCRLWDCET 83
                                   + GHT  +       D K +++ S D + RLW  ET
Sbjct: 341 LLTGSNEKLLKVFDLVNTDAEPKSFAGHTSNIKGALFLSDGKRIISASDDKTVRLWSLET 520

Query: 84  GKQLALLKTNSAVRTCGFDFGGNIIMFSTDKQMGYQCFVSFFDLRDPSQIDSNEPYMKIP 143
            +++  L  ++   +       N I+ +  + +    F     LR+  + ++  P     
Sbjct: 521 CQEVQQLTFDTPPTSLTLSPDKNTIIVTHSQNI---AFYQADTLREMKKFEAEAP----- 676

Query: 144 CNDSKITSAVWGPLGECVIAGHESGELNQYSAKSGEVLVNVKEHSRQINDIQLSRDMTMF 203
                I+SA         +AG E  ++ ++  ++G+ + + K H   ++ ++ S D  ++
Sbjct: 677 -----ISSASLHQSERFFVAGGEDFKMYKFDYETGKEIESFKGHFGPVHCVRFSPDGELY 841

Query: 204 VTASKDNTAKLFDSTTLEHQKTFRTERPVNSAAL--SPNYDHVVLGGGQEAMDVTTTSTR 261
            + S+D T +L+ +T       ++   P  + A   +P+        G+   DV T  TR
Sbjct: 842 ASGSEDGTLRLWQTTIGRTYGLWKCVIPDEADAQNSTPDVKAES*WTGRSDRDVXTAHTR 1021

Query: 262 I 262
           +
Sbjct: 1022L 1024
>01327
          Length = 2215

 Score = 63.5 bits (153), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 58/238 (24%), Positives = 107/238 (44%), Gaps = 11/238 (4%)
 Frame = +3

Query: 8   GHERSITQIKYNREGDLLFTVAKDPIVNVWYSVNGERLGTYMGHTGAVWCVDADWDTKHV 67
           GH+R IT++ Y    + +F+ ++D  + +W   N   +  ++GH   V  +  + D   +
Sbjct: 159 GHDREITKVCYGASCNGMFSASRDKTIKMWQRGNSHSIRDFIGHDMVVTAIHLNTDNTLL 338

Query: 68  LTGSADNSCRLWDCETGKQLALLKTNSAVRTCGFDF----GGNIIMFSTDKQMGYQCFVS 123
            +GS DN+ R+WD ETG   A L+ N+  +    D     G ++I+     Q G    V 
Sbjct: 339 CSGSRDNTVRIWDVETG---ACLRQNNIPQNLVTDVKWLPGSHLII-----QAGEDKEVR 494

Query: 124 FFDLRDPSQIDS--NEPYMKIPCNDSKITSAVWGPLGECVIAGHESGELNQYSAKSGEVL 181
            +D R    + S   + Y+++ C+   +T+     L      G    E   +    G + 
Sbjct: 495 IYDSRTLGIVRSFTKKQYIQMSCD---VTADGQFCLTCSNGFGGNGCEATLWQLSDGSIQ 665

Query: 182 VNVKEHSRQIND---IQLSRDMTMFVTASKDNTAKLFDSTTLE--HQKTFRTERPVNS 234
              K H   I     +  ++DMT+  TAS+D + ++++  T E   ++ F    P+ S
Sbjct: 666 NEFKGHREAIEACLFLPSNQDMTLIATASRDCSVRVWNMFTKECVCEQNFEGTGPLTS 839
>03156
          Length = 1014

 Score = 63.2 bits (152), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 58/238 (24%), Positives = 107/238 (44%), Gaps = 11/238 (4%)
 Frame = +1

Query: 8   GHERSITQIKYNREGDLLFTVAKDPIVNVWYSVNGERLGTYMGHTGAVWCVDADWDTKHV 67
           GH+R IT++ Y    + +F+ ++D  + +W   N   +  ++GH   V  +  + D   +
Sbjct: 49  GHDREITKVCYGASCNGMFSASRDKTIKMWQRGNSHSIRDFIGHDMVVTAIHLNTDNTLL 228

Query: 68  LTGSADNSCRLWDCETGKQLALLKTNSAVRTCGFDF----GGNIIMFSTDKQMGYQCFVS 123
            +GS DN+ R+WD ETG   A L+ N+  +    D     G ++I+     Q G    V 
Sbjct: 229 CSGSRDNTVRIWDVETG---ACLRQNNIPQNLVTDVKWLPGSHLII-----QAGEDKEVR 384

Query: 124 FFDLRDPSQIDS--NEPYMKIPCNDSKITSAVWGPLGECVIAGHESGELNQYSAKSGEVL 181
            +D R    + S   + Y+++ C+   +T+     L      G    E   +    G + 
Sbjct: 385 IYDSRTLGIVRSFTKKQYIQMSCD---VTADGQFCLTCSNGFGGNGCEATLWQLSDGSIQ 555

Query: 182 VNVKEHSRQIND---IQLSRDMTMFVTASKDNTAKLFDSTTLE--HQKTFRTERPVNS 234
              K H   I     +  ++DMT+  TAS+D + ++++  T E   ++ F    P+ S
Sbjct: 556 NEFKGHREAIEACLFLPSNQDMTLIATASRDCSVRVWNMFTKECVCEQNFEGTGPLTS 729
>12574
          Length = 521

 Score = 55.5 bits (132), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 31/107 (28%), Positives = 59/107 (55%), Gaps = 3/107 (2%)
 Frame = +3

Query: 6   LQGHERSITQIKYNREGDLLFTVAKDPIVNVWYSVNGERLGTYMGHTGAVWCVDADW--D 63
           L GH ++++ +K++  GD L + + D ++ +W + +G+   T  GH   +   D  W  D
Sbjct: 174 LAGHTKALSAVKFSPNGDWLASSSADKLIKIWGAYDGKFEKTIAGHKLGL--SDVAWSSD 347

Query: 64  TKHVLTGSADNSCRLWDCETGKQLALLKTNSA-VRTCGFDFGGNIIM 109
           +K + + S D + ++W+  TGK +  LK +S  V  C F+   N+I+
Sbjct: 348 SKLLCSASDDKTLKIWEFSTGKCMKTLKGHSNYVFCCNFNPQSNLIV 488

 Score = 36.6 bits (83), Expect = 0.016,   Method: Compositional matrix adjust.
 Identities = 14/66 (21%), Positives = 36/66 (54%)
 Frame = +3

Query: 6   LQGHERSITQIKYNREGDLLFTVAKDPIVNVWYSVNGERLGTYMGHTGAVWCVDADWDTK 65
           + GH+  ++ + ++ +  LL + + D  + +W    G+ + T  GH+  V+C + +  + 
Sbjct: 300 IAGHKLGLSDVAWSSDSKLLCSASDDKTLKIWEFSTGKCMKTLKGHSNYVFCCNFNPQSN 479

Query: 66  HVLTGS 71
            +++GS
Sbjct: 480 LIVSGS 497
>27465
          Length = 658

 Score = 55.1 bits (131), Expect = 4e-08,   Method: Compositional matrix adjust.
 Identities = 27/82 (32%), Positives = 43/82 (52%), Gaps = 1/82 (1%)
 Frame = -1

Query: 6   LQGHERSITQIKYNRE-GDLLFTVAKDPIVNVWYSVNGERLGTYMGHTGAVWCVDADWDT 64
           L+GH   +  I +N   GD + T + D    +W + +G+   T  GHT  + CV  +  +
Sbjct: 247 LEGHRNVVYAIAFNNPFGDKVITGSFDKTCKLWSTADGKCYHTLRGHTAEIVCVSFNPSS 68

Query: 65  KHVLTGSADNSCRLWDCETGKQ 86
             + TGS D +CRLWD E  ++
Sbjct: 67  TLIATGSMDTTCRLWDVEKAQR 2

 Score = 48.9 bits (115), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 27/96 (28%), Positives = 46/96 (47%), Gaps = 1/96 (1%)
 Frame = -1

Query: 5   LLQGHERSITQIKYNREGDLLFTVAKDPIVNVWYSVNGERLGTYMGHTGAVWCVDADWD- 63
           +L+ H   +T + +N+ G    T + D    +W + + E L T  GH   V+ +  +   
Sbjct: 376 VLRAHILPLTNVAFNKSGSSFITGSYDRTCKIWDTASAEELHTLEGHRNVVYAIAFNNPF 197

Query: 64  TKHVLTGSADNSCRLWDCETGKQLALLKTNSAVRTC 99
              V+TGS D +C+LW    GK    L+ ++A   C
Sbjct: 196 GDKVITGSFDKTCKLWSTADGKCYHTLRGHTAEIVC 89

 Score = 38.5 bits (88), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 28/130 (21%), Positives = 57/130 (43%), Gaps = 2/130 (1%)
 Frame = -1

Query: 184 VKEHSRQINDIQLSRDMTMFVTASKDNTAKLFDSTTLEHQKTFRTERPVNSAAL--SPNY 241
           ++ H   + ++  ++  + F+T S D T K++D+ + E   T    R V  A    +P  
Sbjct: 373 LRAHILPLTNVAFNKSGSSFITGSYDRTCKIWDTASAEELHTLEGHRNVVYAIAFNNPFG 194

Query: 242 DHVVLGGGQEAMDVTTTSTRIGKFEARFFHLAFEEEFGRVKGHFGPINSVAFHPDGKSYS 301
           D V+ G   +   + +T+      + + +H         ++GH   I  V+F+P     +
Sbjct: 193 DKVITGSFDKTCKLWSTA------DGKCYH--------TLRGHTAEIVCVSFNPSSTLIA 56

Query: 302 SGGEDGYVRI 311
           +G  D   R+
Sbjct: 55  TGSMDTTCRL 26
>30256
          Length = 961

 Score = 50.1 bits (118), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 57/230 (24%), Positives = 95/230 (41%), Gaps = 16/230 (6%)
 Frame = +3

Query: 6   LQGHERSITQIKYNREGDLLFTVAKDPIVNVWYSVNGERLGTYMGHTGAVWCVDADWDTK 65
           L GH  ++  +     G  + + ++D  + VW   +G  L   +GH  AV CV   +D K
Sbjct: 150 LYGHSSTVRCLSL--SGKKVVSGSRDATLRVWDIESGHCLNVLLGHMAAVRCV--QYDGK 317

Query: 66  HVLTGSADNSCRLWDCETGKQLALLKTNS-AVRTCGFDFGGNIIMFSTDKQ--------- 115
            V++G+ D + R+WD +T   L  L+ ++  V +  FD G  ++  S D           
Sbjct: 318 RVVSGAXDYTVRVWDPDTASCLHTLQGHTNRVYSLQFD-GVYVVSGSLDTSIRVWDVRCG 494

Query: 116 ------MGYQCFVSFFDLRDPSQIDSNEPYMKIPCNDSKITSAVWGPLGECVIAGHESGE 169
                 MG+Q   S  +L+D   +  N         DS  T  VW               
Sbjct: 495 KLVHTLMGHQSLTSGLELKDNLLVSGNA--------DS--TVKVW--------------- 599

Query: 170 LNQYSAKSGEVLVNVKEHSRQINDIQLSRDMTMFVTASKDNTAKLFDSTT 219
            + ++ K  + L+   +H   +  +Q ++     VT S D T KL+D  T
Sbjct: 600 -DVHTGKCLQTLLGPNKHRSAVTCLQFNKK--FVVTCSDDGTVKLWDLNT 740

 Score = 41.2 bits (95), Expect = 6e-04,   Method: Compositional matrix adjust.
 Identities = 46/206 (22%), Positives = 94/206 (45%), Gaps = 1/206 (0%)
 Frame = +3

Query: 22  GDLLFTVAKDPIVNVWYSVNGERLGTYMGHTGAVWCVDADWDTKHVLTGSADNSCRLWDC 81
           G+ + + + D  + VW +  G    T  GH+  V C+      K V++GS D + R+WD 
Sbjct: 72  GNTVISGSTDRSLKVWNADTGVCTHTLYGHSSTVRCLSL--SGKKVVSGSRDATLRVWDI 245

Query: 82  ETGKQL-ALLKTNSAVRTCGFDFGGNIIMFSTDKQMGYQCFVSFFDLRDPSQIDSNEPYM 140
           E+G  L  LL   +AVR   +D G  ++  + D  +          + DP   D+     
Sbjct: 246 ESGHCLNVLLGHMAAVRCVQYD-GKRVVSGAXDYTV---------RVWDP---DTASCLH 386

Query: 141 KIPCNDSKITSAVWGPLGECVIAGHESGELNQYSAKSGEVLVNVKEHSRQINDIQLSRDM 200
            +  + +++ S  +   G  V++G     +  +  + G+++  +  H    + ++L  + 
Sbjct: 387 TLQGHTNRVYSLQFD--GVYVVSGSLDTSIRVWDVRCGKLVHTLMGHQSLTSGLELKDN- 557

Query: 201 TMFVTASKDNTAKLFDSTTLEHQKTF 226
            + V+ + D+T K++D  T +  +T 
Sbjct: 558 -LLVSGNADSTVKVWDVHTGKCLQTL 632

 Score = 35.8 bits (81), Expect = 0.021,   Method: Compositional matrix adjust.
 Identities = 63/291 (21%), Positives = 114/291 (39%), Gaps = 20/291 (6%)
 Frame = +3

Query: 39  SVNGERLGTYMGHTGAVWCVDADWDTKHVLTGSADNSCRLWDCETGKQLALLKTNSAVRT 98
           +V G  +   +GHTG VW      +T  V++GS D S ++W+ +TG     L  +S+   
Sbjct: 3   AVTGRCIKNLIGHTGGVWSSQMTGNT--VISGSTDRSLKVWNADTGVCTHTLYGHSSTVR 176

Query: 99  CGFDFGGNIIMFSTDKQMGYQCFVSFFDLRDPSQIDSNEPYM-KIPCNDSKITSAVWGPL 157
           C    G  ++  S D  +        +D+     ++    +M  + C             
Sbjct: 177 CLSLSGKKVVSGSRDATL------RVWDIESGHCLNVLLGHMAAVRCVQYD--------- 311

Query: 158 GECVIAGHESGELNQYSAKSGEVLVNVKEHSRQINDIQLSRDMTMFVTASKDNTAKLFD- 216
           G+ V++G     +  +   +   L  ++ H+ ++  +Q   D    V+ S D + +++D 
Sbjct: 312 GKRVVSGAXDYTVRVWDPDTASCLHTLQGHTNRVYSLQF--DGVYVVSGSLDTSIRVWDV 485

Query: 217 ------STTLEHQKTFRTERPVNSAALSPNYDHVVLGGGQEAMDVTT---TSTRIG--KF 265
                  T + HQ         ++  +S N D  V     +  DV T     T +G  K 
Sbjct: 486 RCGKLVHTLMGHQSLTSGLELKDNLLVSGNADSTV-----KVWDVHTGKCLQTLLGPNKH 650

Query: 266 EARFFHLAFEEEF-------GRVKGHFGPINSVAFHPDGKSYSSGGEDGYV 309
            +    L F ++F       G VK     +N+  F  +  +  SGG  G V
Sbjct: 651 RSAVTCLQFNKKFVVTCSDDGTVK--LWDLNTGDFIRNLITLPSGGSGGVV 797
>02090
          Length = 1841

 Score = 49.3 bits (116), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 44/196 (22%), Positives = 80/196 (40%)
 Frame = -3

Query: 21   EGDLLFTVAKDPIVNVWYSVNGERLGTYMGHTGAVWCVDADWDTKHVLTGSADNSCRLWD 80
            +G + F+   D  + VW   N   +  + GHT    C+D   D   + TG  DN+ R WD
Sbjct: 1593 DGKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISPDGTKLWTGGLDNTVRSWD 1414

Query: 81   CETGKQLALLKTNSAVRTCGFDFGGNIIMFSTDKQMGYQCFVSFFDLRDPSQIDSNEPYM 140
               G+QL     +S + + G+   G  +    +         S  ++   S+ D  + ++
Sbjct: 1413 LREGRQLQQHDFSSQIFSLGYCPTGEWLAVGMES--------SNVEVLHHSKPDKYQLHL 1258

Query: 141  KIPCNDSKITSAVWGPLGECVIAGHESGELNQYSAKSGEVLVNVKEHSRQINDIQLSRDM 200
               C    + S  +   G+  ++  +   LN +    G  +   KE S  ++   ++ D 
Sbjct: 1257 HESC----VLSLKFAYCGKWFVSTGKDNLLNAWRTPYGASIFQSKESSSVLS-CDIAADD 1093

Query: 201  TMFVTASKDNTAKLFD 216
               VT S D  A L++
Sbjct: 1092 KYIVTGSGDKKATLYE 1045
>19949
          Length = 903

 Score = 47.0 bits (110), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 48/180 (26%), Positives = 75/180 (41%), Gaps = 1/180 (0%)
 Frame = +2

Query: 34  VNVWYSVNGERLGTYMGHTGAVWCVDADWDTKHVLTGSADNSCRLWDCETGKQLALLKTN 93
           V +W       + TY GHTG V C+    D + + + S D   +LWD   GK L  LK +
Sbjct: 65  VKLWDIRRKGCIYTYKGHTGCVCCLRFSPDGRWIASASEDGLVKLWDLTAGKLLTDLKLH 244

Query: 94  -SAVRTCGFDFGGNIIMFSTDKQMGYQCFVSFFDLRDPSQIDSNEPYMKIPCNDSKITSA 152
             AV T  F     ++   +  +      V F+DL     I + EP        + I S 
Sbjct: 245 RDAVNTIEFHPHEFLLASGSADRT-----VKFWDLETFQLISTTEP------EANSIRSI 391

Query: 153 VWGPLGECVIAGHESGELNQYSAKSGEVLVNVKEHSRQINDIQLSRDMTMFVTASKDNTA 212
           ++ P G C+ +G +   L  Y  +  E+   V     Q+ D+ +S    +  +  K N A
Sbjct: 392 LFHPDGVCLYSGSKD-TLKVYHWEPLELYDTVSVPWGQVCDMSISNTQLIGASFYKTNVA 568

 Score = 36.6 bits (83), Expect = 0.016,   Method: Compositional matrix adjust.
 Identities = 34/162 (20%), Positives = 64/162 (39%), Gaps = 1/162 (0%)
 Frame = +2

Query: 156 PLGECVIAGHESGELNQYSAKSGEVLVNVKEHSRQINDIQLSRDMTMFVTASKDNTAKLF 215
           P G    +G     +  +  +    +   K H+  +  ++ S D     +AS+D   KL+
Sbjct: 23  PYGAYTASGSMDCNVKLWDIRRKGCIYTYKGHTGCVCCLRFSPDGRWIASASEDGLVKLW 202

Query: 216 DSTTLEHQKTFRTER-PVNSAALSPNYDHVVLGGGQEAMDVTTTSTRIGKFEARFFHLAF 274
           D T  +     +  R  VN+    P+    +L  G     V            +F+ L  
Sbjct: 203 DLTAGKLLTDLKLHRDAVNTIEFHPH--EFLLASGSADRTV------------KFWDLET 340

Query: 275 EEEFGRVKGHFGPINSVAFHPDGKSYSSGGEDGYVRIHYFDP 316
            +     +     I S+ FHPDG    SG +D  +++++++P
Sbjct: 341 FQLISTTEPEANSIRSILFHPDGVCLYSGSKDT-LKVYHWEP 463

 Score = 36.2 bits (82), Expect = 0.019,   Method: Compositional matrix adjust.
 Identities = 24/109 (22%), Positives = 55/109 (50%), Gaps = 1/109 (0%)
 Frame = +2

Query: 7   QGHERSITQIKYNREGDLLFTVAKDPIVNVWYSVNGERLGTYMGHTGAVWCVDADWDTKH 66
           +GH   +  ++++ +G  + + ++D +V +W    G+ L     H  AV  ++       
Sbjct: 110 KGHTGCVCCLRFSPDGRWIASASEDGLVKLWDLTAGKLLTDLKLHRDAVNTIEFHPHEFL 289

Query: 67  VLTGSADNSCRLWDCETGKQLALLKTNS-AVRTCGFDFGGNIIMFSTDK 114
           + +GSAD + + WD ET + ++  +  + ++R+  F   G + ++S  K
Sbjct: 290 LASGSADRTVKFWDLETFQLISTTEPEANSIRSILFHPDG-VCLYSGSK 433
>17602
          Length = 481

 Score = 45.8 bits (107), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 32/118 (27%), Positives = 57/118 (48%), Gaps = 5/118 (4%)
 Frame = +3

Query: 6   LQGHERSITQIKYNREGDLLFTVAKDPIVNVWYSVNGERLGTYMGHTG-AVWCVDADWDT 64
           L  H   +T + +NR+G L+ + + D +  +W + +G+ L T +      V  V    + 
Sbjct: 42  LPAHSDPVTAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLXTLIDDDNPPVSFVKFSPNG 221

Query: 65  KHVLTGSADNSCRLWDCETGKQLALLKTNSAVRTCGF-DF---GGNIIMFSTDKQMGY 118
           K++L  + DN+ +LWD   GK L     +   + C F +F   GG  I+  ++  M Y
Sbjct: 222 KYILAATLDNTLKLWDYSKGKCLKTYVGHRNEKYCIFANFSVTGGKWIVSGSEDNMVY 395

 Score = 37.0 bits (84), Expect = 0.010,   Method: Compositional matrix adjust.
 Identities = 19/79 (24%), Positives = 39/79 (49%), Gaps = 3/79 (3%)
 Frame = +3

Query: 5   LLQGHERSITQIKYNREGDLLFTVAKDPIVNVWYSVNGERLGTYMGHTGAVWCVDADWDT 64
           L+      ++ +K++  G  +     D  + +W    G+ L TY+GH    +C+ A++  
Sbjct: 168 LIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYVGHRNEKYCIFANFSV 347

Query: 65  ---KHVLTGSADNSCRLWD 80
              K +++GS DN   +W+
Sbjct: 348 TGGKWIVSGSEDNMVYIWN 404

 Score = 32.7 bits (73), Expect = 0.19,   Method: Compositional matrix adjust.
 Identities = 23/79 (29%), Positives = 35/79 (44%), Gaps = 2/79 (2%)
 Frame = +3

Query: 36  VWYSVNGERLGTYMGHTGAVWCVDADWDTKHVLTGSADNSCRLWDCETGKQLALL--KTN 93
           +W    G+ L T   H+  V  V  + D   +++ S D  CR+WD  +G+ L  L    N
Sbjct: 6   IWDVKTGKCLKTLPAHSDPVTAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLXTLIDDDN 185

Query: 94  SAVRTCGFDFGGNIIMFST 112
             V    F   G  I+ +T
Sbjct: 186 PPVSFVKFSPNGKYILAAT 242

 Score = 29.3 bits (64), Expect = 2.4,   Method: Compositional matrix adjust.
 Identities = 23/116 (19%), Positives = 52/116 (44%), Gaps = 4/116 (3%)
 Frame = +3

Query: 142 IPCNDSKITSAVWGPLGECVIAGHESGELNQYSAKSGEVLVN-VKEHSRQINDIQLSRDM 200
           +P +   +T+  +   G  +++    G    +   SG+ L   + + +  ++ ++ S + 
Sbjct: 42  LPAHSDPVTAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLXTLIDDDNPPVSFVKFSPNG 221

Query: 201 TMFVTASKDNTAKLFDSTTLEHQKTF---RTERPVNSAALSPNYDHVVLGGGQEAM 253
              + A+ DNT KL+D +  +  KT+   R E+    A  S      ++ G ++ M
Sbjct: 222 KYILAATLDNTLKLWDYSKGKCLKTYVGHRNEKYCIFANFSVTGGKWIVSGSEDNM 389

 Score = 27.3 bits (59), Expect = 7.7,   Method: Compositional matrix adjust.
 Identities = 35/152 (23%), Positives = 60/152 (39%), Gaps = 12/152 (7%)
 Frame = +3

Query: 77  RLWDCETGKQLALLKTNS-AVRTCGFDFGGNIIMFST--------DKQMGYQCFVSFFDL 127
           R+WD +TGK L  L  +S  V    F+  G++I+ S+        D   G QC  +  D 
Sbjct: 3   RIWDVKTGKCLKTLPAHSDPVTAVHFNRDGSLIVSSSYDGLCRIWDTASG-QCLXTLID- 176

Query: 128 RDPSQIDSNEPYMKIPCNDSKITSAVWGPLGECVIAGHESGELNQYSAKSGEVLVNVKEH 187
                 D N P          ++   + P G+ ++A      L  +    G+ L     H
Sbjct: 177 ------DDNPP----------VSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYVGH 308

Query: 188 SRQINDIQLSRDMT---MFVTASKDNTAKLFD 216
             +   I  +  +T     V+ S+DN   +++
Sbjct: 309 RNEKYCIFANFSVTGGKWIVSGSEDNMVYIWN 404
>03395
          Length = 2795

 Score = 41.6 bits (96), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 31/138 (22%), Positives = 59/138 (42%)
 Frame = +2

Query: 178 GEVLVNVKEHSRQINDIQLSRDMTMFVTASKDNTAKLFDSTTLEHQKTFRTERPVNSAAL 237
           G+++ N+KEH  ++  IQ+  +    V+AS D +  ++D  T    +             
Sbjct: 116 GDLVANMKEHKGKVTAIQIHTNDRCCVSASTDGSTIIWDLITNTRSQIVLANTLFKCVCF 295

Query: 238 SPNYDHVVLGGGQEAMDVTTTSTRIGKFEARFFHLAFEEEFGRVKGHFGPINSVAFHPDG 297
                H++  G         T  +IG +E     L  E E  +     G IN++    DG
Sbjct: 296 GGKDLHILTSG---------TDHKIGYWEVGDGGLLRELEGSQT----GAINTIDIDRDG 436

Query: 298 KSYSSGGEDGYVRIHYFD 315
           ++  +GGED  +++  ++
Sbjct: 437 QTILTGGEDSLLKLWRYN 490

 Score = 31.6 bits (70), Expect = 0.46,   Method: Compositional matrix adjust.
 Identities = 44/214 (20%), Positives = 79/214 (36%), Gaps = 11/214 (5%)
 Frame = +2

Query: 13  ITQIKYNREGDLLFTVAKDPIVNVWYSVN--------GERLGTYMGHTGAVWCVDADWDT 64
           +T I     G  L +   +  V VW  V         G+ +     H G V  +    + 
Sbjct: 5   VTAIAVTSCGTKLVSGGGEGQVRVWDIVKDMLTGKTRGDLVANMKEHKGKVTAIQIHTND 184

Query: 65  KHVLTGSADNSCRLWDCETGKQLALLKTNSAVRTCGFDFGG---NIIMFSTDKQMGYQCF 121
           +  ++ S D S  +WD  T  +  ++  N+  +     FGG   +I+   TD ++GY   
Sbjct: 185 RCCVSASTDGSTIIWDLITNTRSQIVLANTLFKC--VCFGGKDLHILTSGTDHKIGY--- 349

Query: 122 VSFFDLRDPSQIDSNEPYMKIPCNDSKITSAVWGPLGECVIAGHESGELNQYSAKSGEVL 181
              +++ D   +   E       N   I        G+ ++ G E   L  +    GEV 
Sbjct: 350 ---WEVGDGGLLRELEGSQTGAINTIDIDRD-----GQTILTGGEDSLLKLWRYNEGEVT 505

Query: 182 VNVKEHSRQINDIQLSRDMTMFVTASKDNTAKLF 215
                HS QI   ++  +    V+  +D    ++
Sbjct: 506 HTGIGHSNQITKARICPNRHYIVSGGEDGALHIW 607

 Score = 30.8 bits (68), Expect = 0.87,   Method: Compositional matrix adjust.
 Identities = 15/68 (22%), Positives = 33/68 (48%)
 Frame = +2

Query: 12  SITQIKYNREGDLLFTVAKDPIVNVWYSVNGERLGTYMGHTGAVWCVDADWDTKHVLTGS 71
           +I  I  +R+G  + T  +D ++ +W    GE   T +GH+  +       +  ++++G 
Sbjct: 404 AINTIDIDRDGQTILTGGEDSLLKLWRYNEGEVTHTGIGHSNQITKARICPNRHYIVSGG 583

Query: 72  ADNSCRLW 79
            D +  +W
Sbjct: 584 EDGALHIW 607
>00561
          Length = 1003

 Score = 41.2 bits (95), Expect = 6e-04,   Method: Compositional matrix adjust.
 Identities = 35/153 (22%), Positives = 67/153 (43%), Gaps = 4/153 (2%)
 Frame = -3

Query: 158 GECVIAGHESGELNQYSAKSGEVLVNVKEHSRQINDIQLSRDMTMFVTASKDNTAKLFDS 217
           G   ++G     L  +   +G+     + H++ +  +  S D    V+ S+D T KL++ 
Sbjct: 830 GNYALSGSWDQTLRLWDLAAGKTTRRFEGHTKDVLSVAFSADNRQIVSGSRDKTIKLWN- 654

Query: 218 TTLEHQKTFRTE---RPVNSAALSPNYDH-VVLGGGQEAMDVTTTSTRIGKFEARFFHLA 273
           T  E + T + +     V+    SPN+ + +++  G +                + ++LA
Sbjct: 653 TLAECKFTIQEDGHTDWVSCVRFSPNHSNPIIVSCGWDRT-------------VKVWNLA 513

Query: 274 FEEEFGRVKGHFGPINSVAFHPDGKSYSSGGED 306
             +      GH G +N+V   PDG   +SGG+D
Sbjct: 512 NCKLKNNHHGHNGYLNTVTVSPDGSLCTSGGKD 414

 Score = 37.4 bits (85), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 49/235 (20%), Positives = 90/235 (38%)
 Frame = -3

Query: 6   LQGHERSITQIKYNREGDLLFTVAKDPIVNVWYSVNGERLGTYMGHTGAVWCVDADWDTK 65
           L GH   I+ +  + +G+   + + D  + +W    G+    + GHT  V  V    D +
Sbjct: 878 LYGHSHFISDVVLSSDGNYALSGSWDQTLRLWDLAAGKTTRRFEGHTKDVLSVAFSADNR 699

Query: 66  HVLTGSADNSCRLWDCETGKQLALLKTNSAVRTCGFDFGGNIIMFSTDKQMGYQCFVSFF 125
            +++GS D + +LW+               +  C F          T ++ G+  +VS  
Sbjct: 698 QIVSGSRDKTIKLWN--------------TLAECKF----------TIQEDGHTDWVSCV 591

Query: 126 DLRDPSQIDSNEPYMKIPCNDSKITSAVWGPLGECVIAGHESGELNQYSAKSGEVLVNVK 185
                S   SN   + + C   + T  VW  L  C +  +  G                 
Sbjct: 590 RF---SPNHSNP--IIVSCGWDR-TVKVWN-LANCKLKNNHHG----------------- 483

Query: 186 EHSRQINDIQLSRDMTMFVTASKDNTAKLFDSTTLEHQKTFRTERPVNSAALSPN 240
            H+  +N + +S D ++  +  KD+ A L+D    ++  T      +N+   SPN
Sbjct: 482 -HNGYLNTVTVSPDGSLCTSGGKDSKALLWDLNDGKNLYTLEHNDIINALCFSPN 321

 Score = 29.3 bits (64), Expect = 2.4,   Method: Compositional matrix adjust.
 Identities = 14/44 (31%), Positives = 22/44 (50%)
 Frame = -3

Query: 268 RFFHLAFEEEFGRVKGHFGPINSVAFHPDGKSYSSGGEDGYVRI 311
           R + LA  +   R +GH   + SVAF  D +   SG  D  +++
Sbjct: 791 RLWDLAAGKTTRRFEGHTKDVLSVAFSADNRQIVSGSRDKTIKL 660
>17266
          Length = 480

 Score = 37.4 bits (85), Expect = 0.009,   Method: Compositional matrix adjust.
 Identities = 21/62 (33%), Positives = 29/62 (46%)
 Frame = -1

Query: 13  ITQIKYNREGDLLFTVAKDPIVNVWYSVNGERLGTYMGHTGAVWCVDADWDTKHVLTGSA 72
           IT + +++ G LL     D   N+W  +  ER G   GH   V C+    D   V TGS 
Sbjct: 192 ITSVAFSKSGRLLLGGYDDFNCNIWDVLKQERTGVLAGHDNRVSCLGVTEDGSAVATGSW 13

Query: 73  DN 74
           D+
Sbjct: 12  DS 7

 Score = 28.5 bits (62), Expect = 3.6,   Method: Compositional matrix adjust.
 Identities = 9/30 (30%), Positives = 19/30 (63%)
 Frame = -1

Query: 282 KGHFGPINSVAFHPDGKSYSSGGEDGYVRI 311
            GH   IN++ + P+G ++++G +D   R+
Sbjct: 342 SGHESDINAITYFPNGHAFATGSDDATCRL 253
>12960
          Length = 550

 Score = 37.0 bits (84), Expect = 0.010,   Method: Compositional matrix adjust.
 Identities = 18/50 (36%), Positives = 28/50 (56%)
 Frame = +2

Query: 31  DPIVNVWYSVNGERLGTYMGHTGAVWCVDADWDTKHVLTGSADNSCRLWD 80
           D  V ++   +G+ L  Y  H G V CV  + ++  +L+GS DN+ R WD
Sbjct: 362 DKTVVLFDVASGQALRKYRDHAGTVNCVKFNEESTVILSGSLDNTVRAWD 511
>04524
          Length = 1340

 Score = 36.6 bits (83), Expect = 0.015,   Method: Compositional matrix adjust.
 Identities = 33/99 (33%), Positives = 51/99 (51%), Gaps = 7/99 (7%)
 Frame = -1

Query: 5    LLQGHERSITQIKYN-REGDLLFTVAKDPIVNVWYSVNGERLGTY-MGHTGAVWCVDADW 62
            LL GH   +  +    REG ++ T  +D  + V    N   + TY +GHT  V C+    
Sbjct: 1043 LLLGHLSMVLDVCLTGREGHVV-TCDRDEKIRVSQFPNAYNIHTYCLGHTQFVNCLVYVE 867

Query: 63   DTKHVLTGSADNSCRLWDCETGKQLALL-----KTNSAV 96
            + + +++GS D + R W+ E GKQL L+     +T SAV
Sbjct: 866  EFRVLISGSGDCTVRAWNME-GKQLCLVHCAKEQTXSAV 753
>01805
          Length = 2124

 Score = 36.2 bits (82), Expect = 0.020,   Method: Compositional matrix adjust.
 Identities = 21/84 (25%), Positives = 43/84 (51%), Gaps = 4/84 (4%)
 Frame = -1

Query: 6   LQGHERSITQIKYNREG-DLLFTVAKDPIVNVWYSVNGERLGTYMGHTGAVWCVDADW-- 62
           + GH +++  + +NR    +L + + D  V +W    G+    +  H+  V C   +W  
Sbjct: 588 VTGHTQAVLDLSWNRNARHVLASASADTTVALWDLSEGKMAMNFTQHSREVQC--CNWHP 415

Query: 63  -DTKHVLTGSADNSCRLWDCETGK 85
            + + +LTGS DN+ ++ DC + +
Sbjct: 414 QEEQTLLTGSFDNTVKVVDCRSAE 343
>04088
          Length = 511

 Score = 35.8 bits (81), Expect = 0.024,   Method: Compositional matrix adjust.
 Identities = 24/103 (23%), Positives = 45/103 (43%), Gaps = 4/103 (3%)
 Frame = +3

Query: 11  RSITQIKYNREGDLLFTVAKDPIVNVWYSVNGERLGTYMGHTGAVWCVDADWDTKH--VL 68
           +++T + + R+G      ++D  V +     GE L  + GH  + + +D+  + +   V+
Sbjct: 33  KAVTSVTFTRDGQCSLVSSQDNTVRLMDKDTGEMLNEFTGHKHSQYKIDSCLNNEDTLVV 212

Query: 69  TGSADNSCRLWDCETGKQLALL--KTNSAVRTCGFDFGGNIIM 109
           +GS D     WD    K +  L  KT   V +  F      +M
Sbjct: 213 SGSEDGKVYFWDLVEAKLVDTLDHKTTRPVHSLSFHHAELCLM 341
>15337
          Length = 860

 Score = 35.4 bits (80), Expect = 0.031,   Method: Compositional matrix adjust.
 Identities = 18/47 (38%), Positives = 25/47 (53%)
 Frame = -1

Query: 268 RFFHLAFEEEFGRVKGHFGPINSVAFHPDGKSYSSGGEDGYVRIHYF 314
           R F+    E  G +K +FG +  V + PDGK   +GGED  V +  F
Sbjct: 254 RVFNYNSMELIGTMKSYFGGLLCVCWSPDGKYIVTGGEDDLVTVWSF 114
>17598
          Length = 875

 Score = 35.0 bits (79), Expect = 0.039,   Method: Compositional matrix adjust.
 Identities = 34/162 (20%), Positives = 65/162 (40%), Gaps = 6/162 (3%)
 Frame = +1

Query: 9   HERSITQIKYNREGD--LLFTVAKDPIVNVWYSVNGERLGTYMGHTGAVWCVDADWDTKH 66
           H+  +T +K++++    L+ + + D  + VW +       T++GH   +  +D    T +
Sbjct: 373 HQDWVTCVKFHQDAKSPLVVSASMDKTIKVWDNQTMTLKHTFVGHKTQINAIDLALKTYY 552

Query: 67  VLTGSADNSCRLWDCETGKQLALLKTNSAVRTCGFDFGGNIIMFSTDKQMGYQCFVSFFD 126
           + +GS D     W+ + G  L  +  +  V    F      +   T + +      +   
Sbjct: 553 LASGSKDGIVMTWNIQNGTFLGKIDCDCEVNAVKFSPNKYWLFVGTSEGIQIWDLPNQKK 732

Query: 127 LRD--PSQIDSNEPYMK--IPCNDSKITSAVWGPLGECVIAG 164
           ++D   S ID+     K  I C     TS  W   G  + AG
Sbjct: 733 IKDIRASPIDAQHKSQKKSIAC-----TSLAWDASGHTLFAG 843

 Score = 32.7 bits (73), Expect = 0.22,   Method: Compositional matrix adjust.
 Identities = 52/230 (22%), Positives = 84/230 (36%), Gaps = 7/230 (3%)
 Frame = +1

Query: 47  TYMGHTGAVWCVDADWDTKHVLTGSADNSCRLWDCETGKQLALLKTNSAVRTCGFDFGGN 106
           T  GH+  V  V    D+++VL+ S D + RLWD + G        N+  R         
Sbjct: 106 TLQGHSHFVSDVSLSADSRYVLSSSWDATLRLWDIKKG--------NTTRRFISHTRDAL 261

Query: 107 IIMFSTDKQMGYQCFVSFFDLRDPSQIDS--NEPYMKIPCNDSKITSAVWGPLGECVIAG 164
            + FS D +                QI S   +  +KI           W  +GEC    
Sbjct: 262 AVAFSPDNR----------------QIASGGRDKALKI-----------WNTVGEC---- 348

Query: 165 HESGELNQYSAKSGEVLVNVKEHSRQINDIQLSRDMT--MFVTASKDNTAKLFDSTTLEH 222
                         +  V+   H   +  ++  +D    + V+AS D T K++D+ T+  
Sbjct: 349 --------------KFTVDANSHQDWVTCVKFHQDAKSPLVVSASMDKTIKVWDNQTMTL 486

Query: 223 QKTF---RTERPVNSAALSPNYDHVVLGGGQEAMDVTTTSTRIGKFEARF 269
           + TF   +T+      AL   Y    L  G +   V T + + G F  + 
Sbjct: 487 KHTFVGHKTQINAIDLALKTYY----LASGSKDGIVMTWNIQNGTFLGKI 624

 Score = 30.8 bits (68), Expect = 0.72,   Method: Compositional matrix adjust.
 Identities = 14/75 (18%), Positives = 33/75 (44%)
 Frame = +1

Query: 6   LQGHERSITQIKYNREGDLLFTVAKDPIVNVWYSVNGERLGTYMGHTGAVWCVDADWDTK 65
           LQGH   ++ +  + +   + + + D  + +W    G     ++ HT     V    D +
Sbjct: 109 LQGHSHFVSDVSLSADSRYVLSSSWDATLRLWDIKKGNTTRRFISHTRDALAVAFSPDNR 288

Query: 66  HVLTGSADNSCRLWD 80
            + +G  D + ++W+
Sbjct: 289 QIASGGRDKALKIWN 333
>17298
          Length = 476

 Score = 35.0 bits (79), Expect = 0.046,   Method: Compositional matrix adjust.
 Identities = 16/40 (40%), Positives = 24/40 (60%)
 Frame = -1

Query: 41  NGERLGTYMGHTGAVWCVDADWDTKHVLTGSADNSCRLWD 80
           +G+ L  Y  H G V CV  + ++  +L+GS DN+ R WD
Sbjct: 245 SGQALRKYRDHAGTVNCVKFNEESTVILSGSLDNTVRAWD 126
>21921
          Length = 1341

 Score = 34.7 bits (78), Expect = 0.057,   Method: Compositional matrix adjust.
 Identities = 15/65 (23%), Positives = 33/65 (50%)
 Frame = -1

Query: 47  TYMGHTGAVWCVDADWDTKHVLTGSADNSCRLWDCETGKQLALLKTNSAVRTCGFDFGGN 106
            Y GHTG V  +  D   + +++GS D + R W+  +G+ +  L+    V +  ++   +
Sbjct: 498 VYKGHTGIVRSICPDPTGQWLVSGSDDGTIRFWEVSSGRCMKTLQVGGCVTSVAWNPNPS 319

Query: 107 IIMFS 111
           + + +
Sbjct: 318 LCVVA 304

 Score = 28.9 bits (63), Expect = 3.2,   Method: Compositional matrix adjust.
 Identities = 12/29 (41%), Positives = 17/29 (58%)
 Frame = -1

Query: 282 KGHFGPINSVAFHPDGKSYSSGGEDGYVR 310
           KGH G + S+   P G+   SG +DG +R
Sbjct: 492 KGHTGIVRSICPDPTGQWLVSGSDDGTIR 406
>36111
          Length = 687

 Score = 33.9 bits (76), Expect = 0.10,   Method: Compositional matrix adjust.
 Identities = 13/25 (52%), Positives = 19/25 (76%)
 Frame = +2

Query: 287 PINSVAFHPDGKSYSSGGEDGYVRI 311
           P+N+VAFH    ++++GG DGYV I
Sbjct: 236 PVNAVAFHNVYNTFATGGSDGYVNI 310
>35607
          Length = 475

 Score = 33.5 bits (75), Expect = 0.11,   Method: Compositional matrix adjust.
 Identities = 33/154 (21%), Positives = 63/154 (40%)
 Frame = +2

Query: 63  DTKHVLTGSADNSCRLWDCETGKQLALLKTNSAVRTCGFDFGGNIIMFSTDKQMGYQCFV 122
           D   + TG  DN+ R WD   G+QL     +S + + G+   G+ +    +         
Sbjct: 11  DGTKLWTGGLDNTVRSWDLREGRQLQQHDFSSQIFSLGYCPTGDWLAVGMES-------- 166

Query: 123 SFFDLRDPSQIDSNEPYMKIPCNDSKITSAVWGPLGECVIAGHESGELNQYSAKSGEVLV 182
           S  ++   S+ D  + ++   C    + S  +   G+  ++  +   LN +    G  + 
Sbjct: 167 SNVEVLHHSKPDKYQLHLHESC----VLSLKFAYCGKWFVSTGKDNLLNAWRTPYGASIF 334

Query: 183 NVKEHSRQINDIQLSRDMTMFVTASKDNTAKLFD 216
             KE S  ++   ++ D    VT S D  A L++
Sbjct: 335 QSKESSSVLS-CDIAADDKYIVTGSGDKKATLYE 433
>14555
          Length = 627

 Score = 33.1 bits (74), Expect = 0.14,   Method: Compositional matrix adjust.
 Identities = 20/57 (35%), Positives = 26/57 (45%)
 Frame = -3

Query: 23  DLLFTVAKDPIVNVWYSVNGERLGTYMGHTGAVWCVDADWDTKHVLTGSADNSCRLW 79
           D    V  D  VNVW ++ G R     GH   V C+    D   + TGS D + R+W
Sbjct: 427 DCCLGVTNDYTVNVWDALKGMRSTILYGHDNRVSCLRISPDGTSLCTGSWDYTLRIW 257

 Score = 32.0 bits (71), Expect = 0.35,   Method: Compositional matrix adjust.
 Identities = 11/30 (36%), Positives = 19/30 (63%)
 Frame = -2

Query: 282 KGHFGPINSVAFHPDGKSYSSGGEDGYVRI 311
           +GH   IN V F+P G ++++G +D   R+
Sbjct: 608 EGHEADINCVRFYPSGDAFATGSDDATCRL 519

 Score = 30.8 bits (68), Expect = 0.70,   Method: Compositional matrix adjust.
 Identities = 21/80 (26%), Positives = 35/80 (43%), Gaps = 3/80 (3%)
 Frame = -2

Query: 43  ERLGTYMGHTGAVWCVDADWDTKHVLTGSADNSCRLWDCETGKQLALLKTNSAVRTCGFD 102
           E +  + GH   + CV          TGS D +CRL+D    +++   +  S +      
Sbjct: 626 ECVQMFEGHEADINCVRFYPSGDAFATGSDDATCRLFDLRADREVNCYRKESII------ 465

Query: 103 FGGNIIMFSTDKQM---GYQ 119
           FG N + FS   ++   GY+
Sbjct: 464 FGCNAVDFSVSGRLLFGGYE 405
>15780
          Length = 735

 Score = 32.7 bits (73), Expect = 0.22,   Method: Compositional matrix adjust.
 Identities = 19/56 (33%), Positives = 25/56 (44%)
 Frame = -1

Query: 25  LFTVAKDPIVNVWYSVNGERLGTYMGHTGAVWCVDADWDTKHVLTGSADNSCRLWD 80
           L T   D  V VW   +G  +     HT  V+ +    D   + +G  DNS RLWD
Sbjct: 729 LSTAGADHTVIVWDIASGTAVAHLTAHTDTVYALCFSRDGTVLASGGMDNSIRLWD 562

 Score = 29.6 bits (65), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 19/72 (26%), Positives = 37/72 (51%)
 Frame = -1

Query: 177 SGEVLVNVKEHSRQINDIQLSRDMTMFVTASKDNTAKLFDSTTLEHQKTFRTERPVNSAA 236
           SG  + ++  H+  +  +  SRD T+  +   DN+ +L+D   +  ++   T+  V S +
Sbjct: 681 SGTAVAHLTAHTDTVYALCFSRDGTVLASGGMDNSIRLWDLARVMEEQDPETDSNVPS-S 505

Query: 237 LSPNYDHVVLGG 248
           LS N +  +L G
Sbjct: 504 LSVNTNPALLLG 469
>18981
          Length = 407

 Score = 32.0 bits (71), Expect = 0.34,   Method: Compositional matrix adjust.
 Identities = 28/120 (23%), Positives = 48/120 (40%), Gaps = 20/120 (16%)
 Frame = -2

Query: 23  DLLFTVAKDPIVNVWYSVNGERLGTYMGHTGAVWCVDADWDTKHVLTGSADNSCRLWDCE 82
           +++ + A D  + VW   N   L T  GH   V CV      + V++GS D +  +W+ +
Sbjct: 385 NMIISAATDRTLRVWCLKNTCLLHTLRGHNDDVECVCI--YGRRVVSGSWDKTLIVWEVD 212

Query: 83  TGKQLALL--------------------KTNSAVRTCGFDFGGNIIMFSTDKQMGYQCFV 122
           TG+ +  L                      +  VRT   D G  ++  +T + +   C V
Sbjct: 211 TGRPVHQLHGHTEAITAVQFDEGKAVSGSADGDVRTWALDTGQCLLTMTTGQDIEVYCVV 32
>19498
          Length = 903

 Score = 31.6 bits (70), Expect = 0.48,   Method: Compositional matrix adjust.
 Identities = 23/96 (23%), Positives = 45/96 (46%), Gaps = 1/96 (1%)
 Frame = -1

Query: 6   LQGHERSITQIKYNREGDLLFTVAKDPIVNVWYSVN-GERLGTYMGHTGAVWCVDADWDT 64
           L+GH   +  + ++ +   L + + D  + VW ++   E++    GH G V  V  D   
Sbjct: 621 LRGHAGDVLDLAWSPQDLWLASCSVDNTIVVWNALKFSEQVAVIRGHAGMVKGVTWDPVG 442

Query: 65  KHVLTGSADNSCRLWDCETGKQLALLKTNSAVRTCG 100
           +++ + S D + R+W     K+   +K  S  + CG
Sbjct: 441 RYLASQSDDKTLRVWRTSDWKEETCVK--SCFKECG 340

 Score = 28.1 bits (61), Expect = 5.7,   Method: Compositional matrix adjust.
 Identities = 11/28 (39%), Positives = 17/28 (60%)
 Frame = -1

Query: 284 HFGPINSVAFHPDGKSYSSGGEDGYVRI 311
           H G +N V +  +GK  +SGG+D  + I
Sbjct: 789 HLGCVNCVRWSENGKFLASGGDDKLIMI 706
>19863
          Length = 502

 Score = 31.2 bits (69), Expect = 0.58,   Method: Compositional matrix adjust.
 Identities = 21/70 (30%), Positives = 34/70 (48%)
 Frame = +1

Query: 21 EGDLLFTVAKDPIVNVWYSVNGERLGTYMGHTGAVWCVDADWDTKHVLTGSADNSCRLWD 80
          +G  L + + D  + VW   NG +     GH G V  V    D   +L+ S DN+ R+W+
Sbjct: 4  DGLQLVSGSSDMSIVVWDVENGVQKLRLQGHAGWVNDVHFSQDQCWLLSCSNDNTVRIWN 183

Query: 81 CETGKQLALL 90
           E   Q+ ++
Sbjct: 184IEESDQIPIV 213

 Score = 30.4 bits (67), Expect = 0.93,   Method: Compositional matrix adjust.
 Identities = 11/56 (19%), Positives = 31/56 (55%)
 Frame = +1

Query: 161 VIAGHESGELNQYSAKSGEVLVNVKEHSRQINDIQLSRDMTMFVTASKDNTAKLFD 216
           +++G     +  +  ++G   + ++ H+  +ND+  S+D    ++ S DNT ++++
Sbjct: 16  LVSGSSDMSIVVWDVENGVQKLRLQGHAGWVNDVHFSQDQCWLLSCSNDNTVRIWN 183
>13278
          Length = 870

 Score = 31.2 bits (69), Expect = 0.64,   Method: Compositional matrix adjust.
 Identities = 24/88 (27%), Positives = 38/88 (43%), Gaps = 9/88 (10%)
 Frame = +1

Query: 6   LQGHERSITQIKYNREGD---------LLFTVAKDPIVNVWYSVNGERLGTYMGHTGAVW 56
           LQ   + I  IK++  G          +L + + D  V +W    G  L T   H   V+
Sbjct: 37  LQLTTKEIYTIKWSPTGPGTSNPNTSLILASASFDSTVRLWEVERGLCLHTLTKHQEPVY 216

Query: 57  CVDADWDTKHVLTGSADNSCRLWDCETG 84
            V    D K++ +GS D    +W+ +TG
Sbjct: 217 SVAFSPDGKYLASGSFDKCVHIWNVQTG 300

 Score = 30.0 bits (66), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 15/28 (53%), Positives = 17/28 (60%)
 Frame = +1

Query: 284 HFGPINSVAFHPDGKSYSSGGEDGYVRI 311
           H  P+ SVAF PDGK  +SG  D  V I
Sbjct: 199 HQEPVYSVAFSPDGKYLASGSFDKCVHI 282
>15118
          Length = 1074

 Score = 30.8 bits (68), Expect = 0.78,   Method: Compositional matrix adjust.
 Identities = 13/44 (29%), Positives = 22/44 (50%)
 Frame = +3

Query: 5   LLQGHERSITQIKYNREGDLLFTVAKDPIVNVWYSVNGERLGTY 48
           +  GH  SIT + ++ +G  L T + D  V  W  V+G  +  +
Sbjct: 438 VFSGHSNSITDLSFSGDGRWLITASMDCTVRTWSLVHGRLIDCF 569

 Score = 30.8 bits (68), Expect = 0.80,   Method: Compositional matrix adjust.
 Identities = 19/84 (22%), Positives = 40/84 (47%)
 Frame = +3

Query: 13  ITQIKYNREGDLLFTVAKDPIVNVWYSVNGERLGTYMGHTGAVWCVDADWDTKHVLTGSA 72
           I++I  +R+ ++L  V +D  V+V        +  + GH+ ++  +    D + ++T S 
Sbjct: 336 ISRILLHRDSNMLAVVLEDFTVSVIDVDTLRVVRVFSGHSNSITDLSFSGDGRWLITASM 515

Query: 73  DNSCRLWDCETGKQLALLKTNSAV 96
           D + R W    G+ +      +AV
Sbjct: 516 DCTVRTWSLVHGRLIDCFAVEAAV 587
>12806
          Length = 961

 Score = 30.4 bits (67), Expect = 0.91,   Method: Compositional matrix adjust.
 Identities = 15/75 (20%), Positives = 32/75 (42%)
 Frame = +3

Query: 6   LQGHERSITQIKYNREGDLLFTVAKDPIVNVWYSVNGERLGTYMGHTGAVWCVDADWDTK 65
           L GH   I+ +  + +     + + D  + +W    G     ++ HT  V  V    D +
Sbjct: 153 LTGHSHFISDLALSADSRFALSSSWDATLRLWDIKKGSTTSRFINHTRDVLTVAFSPDNR 332

Query: 66  HVLTGSADNSCRLWD 80
            + +G  D + ++W+
Sbjct: 333 QIASGGRDKNLKIWN 377

 Score = 29.6 bits (65), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 17/101 (16%), Positives = 44/101 (43%), Gaps = 2/101 (1%)
 Frame = +3

Query: 8   GHERSITQIKYNRE--GDLLFTVAKDPIVNVWYSVNGERLGTYMGHTGAVWCVDADWDTK 65
            H   +T ++++++    ++ + + D  + VW +       T++GH   +  +D    T 
Sbjct: 414 AHTDWVTCVRFHQDTKNPIVVSASNDKTIKVWDNHTMTLKNTFVGHKAQITALDM--STN 587

Query: 66  HVLTGSADNSCRLWDCETGKQLALLKTNSAVRTCGFDFGGN 106
           ++++GS D     W+   G  +  +  +  +    F+   N
Sbjct: 588 YLVSGSKDGIAMTWNVAEGSFVGKIDCDDQINAIKFNIENN 710

 Score = 28.1 bits (61), Expect = 5.7,   Method: Compositional matrix adjust.
 Identities = 21/80 (26%), Positives = 39/80 (48%), Gaps = 4/80 (5%)
 Frame = +3

Query: 8   GHERSITQIKYNREGDLLFTVAKDPIVNVWYSVNGERLGTY--MGHTGAVWCVDADWDTK 65
            H R +  + ++ +   + +  +D  + +W ++ GE   T     HT  V CV    DTK
Sbjct: 285 NHTRDVLTVAFSPDNRQIASGGRDKNLKIW-NIMGECKYTVDANAHTDWVTCVRFHQDTK 461

Query: 66  H--VLTGSADNSCRLWDCET 83
           +  V++ S D + ++WD  T
Sbjct: 462 NPIVVSASNDKTIKVWDNHT 521
>13335
          Length = 863

 Score = 30.4 bits (67), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 43/227 (18%), Positives = 90/227 (39%), Gaps = 18/227 (7%)
 Frame = +1

Query: 10  ERSITQIKYNREGDLLFTVAKDPIVNVWYSVNGERLGTYMGHTGAVWCVDADWDTKHVLT 69
           + SI   K++     L + + D  + +W     + + +Y+GH  +V  +    +  ++++
Sbjct: 61  KSSIRVCKFSPSSSHLVSGSDDDTICMWEVATQKLVRSYVGHEDSVMALAYSPNGHYLVS 240

Query: 70  GSADNSCRLWDCETGKQLAL-LKTNS---AVRTCGFD--FGGNIIMFSTDKQM-----GY 118
           GS +    +WD   G    L L+ ++    V  C F   FG      S+   +     G 
Sbjct: 241 GSPNGDLYVWDASFGHCRHLTLRVDAHDLGVTCCEFSPTFGTACAENSSTCNLLLATGGK 420

Query: 119 QCFVSFFDLRDPSQIDSNEPYMKIPCND------SKITSAVWGPLGECVIAGHESGELNQ 172
              +  +     +Q+ S  P + + C D        + +  + P    + +G     +  
Sbjct: 421 DNLIKLWTF--SAQVGS--PEVTLQCRDILSGHSDLVMACAFSPSSALLASGSFDKSVRL 588

Query: 173 YSAKSGEVLVNVKE-HSRQINDIQLSRDMTMFVTASKDNTAKLFDST 218
           + +  G  L +++  HSR +     S D T+  + S D   K++  T
Sbjct: 589 WDSVKGVALFSIEACHSRFVTCCAFSIDGTLLASGSMDRIIKIWKLT 729

 Score = 27.7 bits (60), Expect = 6.7,   Method: Compositional matrix adjust.
 Identities = 28/120 (23%), Positives = 46/120 (38%), Gaps = 10/120 (8%)
 Frame = +1

Query: 24  LLFTVAKDPIVNVWY--------SVNGERLGTYMGHTGAVWCVDADWDTKHVLTGSADNS 75
           LL T  KD ++ +W          V  +      GH+  V        +  + +GS D S
Sbjct: 400 LLATGGKDNLIKLWTFSAQVGSPEVTLQCRDILSGHSDLVMACAFSPSSALLASGSFDKS 579

Query: 76  CRLWDCETGKQLALLKTNSA--VRTCGFDFGGNIIMFSTDKQMGYQCFVSFFDLRDPSQI 133
            RLWD   G  L  ++   +  V  C F   G ++   +  ++     +  + L D S I
Sbjct: 580 VRLWDSVKGVALFSIEACHSRFVTCCAFSIDGTLLASGSMDRI-----IKIWKLTDTSSI 744
>03464
          Length = 2588

 Score = 30.0 bits (66), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 15/59 (25%), Positives = 27/59 (45%)
 Frame = -1

Query: 11   RSITQIKYNREGDLLFTVAKDPIVNVWYSVNGERLGTYMGHTGAVWCVDADWDTKHVLT 69
            R++ Q   N+    LF    +P++ + + + G  L   M  +G  WC    W + HV+ 
Sbjct: 1010 RALKQFSENQGV*RLFKACMNPVM-I*WEMKGLGLCHKMAASGMTWCTLLKWFSSHVMC 837
>21105
          Length = 650

 Score = 30.0 bits (66), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 27/114 (23%), Positives = 47/114 (41%), Gaps = 2/114 (1%)
 Frame = +1

Query: 200 MTMFVTASKDNTAKLFDSTT--LEHQKTFRTERPVNSAALSPNYDHVVLGGGQEAMDVTT 257
           M + +TA +D   + FD+ T  L H      +  V S A+ PN  +++ G    ++ +  
Sbjct: 100 MPITITAHEDRHIRFFDNNTGKLIHAMVAHLDS-VTSLAVDPNGLYLLSGSHDCSIRLWN 276

Query: 258 TSTRIGKFEARFFHLAFEEEFGRVKGHFGPINSVAFHPDGKSYSSGGEDGYVRI 311
             ++    E       F+E           I+ VAFHP     +S G D   ++
Sbjct: 277 LDSKTCVQEITSHRKKFDES----------IHDVAFHPQKPYIASAGADALAKV 408
>19140
          Length = 573

 Score = 30.0 bits (66), Expect = 1.4,   Method: Compositional matrix adjust.
 Identities = 14/60 (23%), Positives = 28/60 (46%)
 Frame = -3

Query: 2   KPILLQGHERSITQIKYNREGDLLFTVAKDPIVNVWYSVNGERLGTYMGHTGAVWCVDAD 61
           K + L+GH  ++  +  NR+G    + + D  + +W       + T+  H   VW + A+
Sbjct: 511 KLMKLKGHTDNVKALVLNRDGTQCLSGSSDGTIRLWSLGQQRCVATFRVHDEGVWALQAN 332
>10162
          Length = 1629

 Score = 30.0 bits (66), Expect = 1.4,   Method: Compositional matrix adjust.
 Identities = 18/70 (25%), Positives = 30/70 (42%)
 Frame = +3

Query: 9   HERSITQIKYNREGDLLFTVAKDPIVNVWYSVNGERLGTYMGHTGAVWCVDADWDTKHVL 68
           H   + +++++    LL+T   D ++ VW + +G                     +K VL
Sbjct: 639 HPEGVCKLQWSSSTALLYTACLDGVMRVWDARSGA--------------------SKAVL 758

Query: 69  TGSADNSCRL 78
           TG A NSC L
Sbjct: 759 TGHARNSCIL 788
>31384
          Length = 474

 Score = 29.6 bits (65), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 17/58 (29%), Positives = 32/58 (55%), Gaps = 1/58 (1%)
 Frame = -1

Query: 176 KSGEVLVNVKE-HSRQINDIQLSRDMTMFVTASKDNTAKLFDSTTLEHQKTFRTERPV 232
           +SG+ +   ++ H+  + D+  S D T   TAS D TAK++D  + +  +  + + PV
Sbjct: 174 QSGQTIPKAQQTHTGPVLDVDWSDDGTKVFTASCDKTAKVWDLNSNQCMQIAQHDAPV 1

 Score = 28.5 bits (62), Expect = 3.4,   Method: Compositional matrix adjust.
 Identities = 15/48 (31%), Positives = 26/48 (54%), Gaps = 2/48 (4%)
 Frame = -1

Query: 51  HTGAVWCVDADW--DTKHVLTGSADNSCRLWDCETGKQLALLKTNSAV 96
           HTG V  +D DW  D   V T S D + ++WD  + + + + + ++ V
Sbjct: 138 HTGPV--LDVDWSDDGTKVFTASCDKTAKVWDLNSNQCMQIAQHDAPV 1
>11493
          Length = 535

 Score = 29.6 bits (65), Expect = 1.7,   Method: Compositional matrix adjust.
 Identities = 16/62 (25%), Positives = 27/62 (43%)
 Frame = -2

Query: 16  IKYNREGDLLFTVAKDPIVNVWYSVNGERLGTYMGHTGAVWCVDADWDTKHVLTGSADNS 75
           +  + +  + F+   D  + VW   N   +  + GHT    C+D   D   + TG  DN+
Sbjct: 189 LAISPDSKVCFSCCSDGNIAVWDLHNEILVRQFQGHTDGASCIDISPDGSRLWTGGLDNT 10

Query: 76  CR 77
            R
Sbjct: 9   VR 4
>27525
          Length = 828

 Score = 29.3 bits (64), Expect = 2.2,   Method: Compositional matrix adjust.
 Identities = 10/25 (40%), Positives = 17/25 (68%)
 Frame = +2

Query: 288 INSVAFHPDGKSYSSGGEDGYVRIH 312
           IN+++F PDG   + G  DG+V ++
Sbjct: 77  INAISFSPDGSQLAVGCHDGFVHVY 151
>36348
          Length = 239

 Score = 29.3 bits (64), Expect = 2.4,   Method: Compositional matrix adjust.
 Identities = 17/60 (28%), Positives = 28/60 (46%)
 Frame = -1

Query: 219 TLEHQKTFRTERPVNSAALSPNYDHVVLGGGQEAMDVTTTSTRIGKFEARFFHLAFEEEF 278
           T  H       R +NS +L+ ++  +V GGGQE     +   ++G F    F L + + F
Sbjct: 230 TDSHPYDMYVHRDINSCSLTISFISLVRGGGQEY*YPPSNIKQLGVFSVNSFTLDYLDLF 51
>15972
          Length = 1069

 Score = 29.3 bits (64), Expect = 2.5,   Method: Compositional matrix adjust.
 Identities = 11/29 (37%), Positives = 17/29 (58%)
 Frame = +3

Query: 283 GHFGPINSVAFHPDGKSYSSGGEDGYVRI 311
           GH GP+  +A HP GK   +  +D  +R+
Sbjct: 231 GHKGPVRHLAVHPSGKLTLTVSQDRTLRL 317

 Score = 27.3 bits (59), Expect = 9.1,   Method: Compositional matrix adjust.
 Identities = 10/35 (28%), Positives = 20/35 (57%)
 Frame = +3

Query: 8   GHERSITQIKYNREGDLLFTVAKDPIVNVWYSVNG 42
           GH+  +  +  +  G L  TV++D  + +W ++NG
Sbjct: 231 GHKGPVRHLAVHPSGKLTLTVSQDRTLRLWNNMNG 335
>01249
          Length = 1743

 Score = 28.9 bits (63), Expect = 2.6,   Method: Compositional matrix adjust.
 Identities = 15/48 (31%), Positives = 26/48 (54%)
 Frame = -1

Query: 42  GERLGTYMGHTGAVWCVDADWDTKHVLTGSADNSCRLWDCETGKQLAL 89
           GER+    GH+ AV C+    D + + +GS +    +W+ E+G   +L
Sbjct: 939 GERV--LQGHSDAVTCLAFSSDGQRLASGSQNGKVIIWNMESGDSTSL 802

 Score = 28.1 bits (61), Expect = 5.0,   Method: Compositional matrix adjust.
 Identities = 26/111 (23%), Positives = 47/111 (42%), Gaps = 2/111 (1%)
 Frame = -1

Query: 203  FVTASKDNTAKLFDSTTLEHQKTFRTERPVNSAALSPNYDHVVLGGGQEAMDVTTTSTRI 262
              ++S D T KL+D  +    +T   E  V    +    +H +L G     D+  +    
Sbjct: 1161 VASSSSDGTCKLWDMLSGALLRTMVYETGVGCLIMD-KQEHFLLAGLDNG-DILCSPLFG 988

Query: 263  GKFEARFFHLAFEEEFGR--VKGHFGPINSVAFHPDGKSYSSGGEDGYVRI 311
               ++  F      + G   ++GH   +  +AF  DG+  +SG ++G V I
Sbjct: 987  QISQSEVFVSKHTTKAGERVLQGHSDAVTCLAFSSDGQRLASGSQNGKVII 835
>14500
          Length = 1238

 Score = 28.5 bits (62), Expect = 3.4,   Method: Compositional matrix adjust.
 Identities = 15/48 (31%), Positives = 23/48 (47%)
 Frame = +3

Query: 36  VWYSVNGERLGTYMGHTGAVWCVDADWDTKHVLTGSADNSCRLWDCET 83
           +W      R+    GHT  V  +    D + V++ +AD + RLW C T
Sbjct: 417 IWKYPAMSRVAELTGHTARVLHMAMSPDGETVVSAAADETLRLWKCFT 560
>02960
          Length = 1577

 Score = 28.5 bits (62), Expect = 3.5,   Method: Compositional matrix adjust.
 Identities = 54/276 (19%), Positives = 101/276 (36%), Gaps = 17/276 (6%)
 Frame = +2

Query: 64  TKHV---LTGSADNSCRLWDCETGKQLALLKTNSAVRTCGFDFGGNIIMFSTDKQMGYQC 120
           T+H    L+GS DN+ RLW  + G+ +  +  +++   C       +     D+  G   
Sbjct: 506 TRHTGXXLSGSYDNTVRLWSTK-GEAIMTIPGHTSPVKC-------VAWIKHDESSGVST 661

Query: 121 FVSFFDLRDPSQIDSNEPYMKIPCNDSKITSAVWGPLGECVIAGHESGELNQYSAKSGEV 180
           FV+                          T+ VW                 Q+  ++ EV
Sbjct: 662 FVT---------------------GSHDQTALVW-----------------QWQRETNEV 727

Query: 181 --LVNVKEHSRQINDIQLSRDMTMFVTASKDNTAKLFDS-TTLEHQKTFRTERPVNSAAL 237
              ++ + H+  ++ + +S D     T S D   KL+ +   ++  ++  TERP      
Sbjct: 728 DCRLSCRGHAASVDCVAVSPDSQQMCTGSWDKMLKLWSTDCNVDGDQSEDTERPSKKKKS 907

Query: 238 SPNYDH-----VVLGGGQEA------MDVTTTSTRIGKFEARFFHLAFEEEFGRVKGHFG 286
           + +        + L G  EA      +D     T       R + L   ++   ++G   
Sbjct: 908 AKSTTQTRVPVLTLSGHAEAVSAVRWLDPHRVVTSSWDHSLRLWDLHTAQQTSLIQGSKA 1087

Query: 287 PINSVAFHPDGKSYSSGGEDGYVRIHYFDPQYFEFE 322
            ++ VA+ P      +G  D +VR+   DP+  E E
Sbjct: 1088VLD-VAYSPLSHMLITGSADRHVRL--VDPRCSEGE 1186
>38177
          Length = 430

 Score = 28.5 bits (62), Expect = 4.1,   Method: Compositional matrix adjust.
 Identities = 19/87 (21%), Positives = 36/87 (41%), Gaps = 1/87 (1%)
 Frame = +3

Query: 154 WGPLGECVIAGHESGELNQYSAKSGEVLVNVKEHSRQINDIQLSRDMTMFVTASKDNTAK 213
           W P G  ++ G  SGE   ++  +      ++ H   +  ++ S      VTA      K
Sbjct: 12  WTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDVSVRAMRWSNHDQWMVTADHSGYIK 191

Query: 214 LFDSTTLEHQKTFRTER-PVNSAALSP 239
            + S  + + K F+  + P+    L+P
Sbjct: 192 YWQS-NMNNVKMFQGHKEPIRGVRLAP 269
>30297
          Length = 822

 Score = 28.5 bits (62), Expect = 4.1,   Method: Compositional matrix adjust.
 Identities = 18/77 (23%), Positives = 37/77 (48%), Gaps = 10/77 (12%)
 Frame = -1

Query: 13  ITQIKYNREGDLLFTVAKDPIVNVW----YSV------NGERLGTYMGHTGAVWCVDADW 62
           ++ +  N+   LL++      + VW    Y +      + + + ++ GH  +V C+D   
Sbjct: 375 VSAMATNKANTLLYSADSLGFIYVWDISQYCLETPETDSPDVIQSWRGHVESVSCLDLVE 196

Query: 63  DTKHVLTGSADNSCRLW 79
             K +LT +AD + R+W
Sbjct: 195 QNKVLLTSAADCTVRMW 145
>18320
          Length = 450

 Score = 28.5 bits (62), Expect = 4.4,   Method: Compositional matrix adjust.
 Identities = 11/31 (35%), Positives = 19/31 (61%)
 Frame = -2

Query: 50  GHTGAVWCVDADWDTKHVLTGSADNSCRLWD 80
            H+G +WC+ +    +H+ TGS D   ++WD
Sbjct: 131 AHSGWIWCMASL--NQHLYTGSWDTKIKVWD 45
>10824
          Length = 1751

 Score = 28.1 bits (61), Expect = 5.0,   Method: Compositional matrix adjust.
 Identities = 19/51 (37%), Positives = 25/51 (49%), Gaps = 7/51 (13%)
 Frame = -3

Query: 55   VWCVDADWDTKHVLTGSADNSCRLWDCETG-------KQLALLKTNSAVRT 98
            VWC ++     HVL GS + + RL   + G       KQL  L+T S  RT
Sbjct: 1209 VWCNNSQLPVDHVLAGSFETAMRLLHDQVGVVQFDQYKQL-FLQTYSRART 1060
>01462
          Length = 995

 Score = 28.1 bits (61), Expect = 5.7,   Method: Compositional matrix adjust.
 Identities = 21/95 (22%), Positives = 37/95 (38%), Gaps = 1/95 (1%)
 Frame = +2

Query: 25  LFTVAKDPIVNVWYSVNGERLGTYMGHTGAVWCVDADWDTKHVLTGSADNSCRLWDCETG 84
           L+  A D  ++VW    G+ L    GH   +  V    D +  ++ S D + R+WD  + 
Sbjct: 242 LYAGAGDRKIHVWDIEAGQYLNAMEGHKDYIHKVVMKNDAQECVSASEDGTVRMWDIRSS 421

Query: 85  KQLALLKTNSAVRTCGFDFGGNII-MFSTDKQMGY 118
            +       S    C     G  +   + D + G+
Sbjct: 422 TETVHCLEPSKNELCSRPLLGKWLRCLALDPEEGW 526
>27806
          Length = 419

 Score = 27.3 bits (59), Expect = 8.5,   Method: Compositional matrix adjust.
 Identities = 18/69 (26%), Positives = 32/69 (46%), Gaps = 1/69 (1%)
 Frame = -1

Query: 15  QIKYNREG-DLLFTVAKDPIVNVWYSVNGERLGTYMGHTGAVWCVDADWDTKHVLTGSAD 73
           ++  +R G  ++ T + D    ++    G  + TY GH G+V  V        VLT S D
Sbjct: 413 EVSVSRPGHPIIGTASADHTARIYSIETGACVLTYGGHQGSVNAVRFHPGQDLVLTASGD 234

Query: 74  NSCRLWDCE 82
           ++  +W  +
Sbjct: 233 HTAHVWRAQ 207
>03387
          Length = 1891

 Score = 27.3 bits (59), Expect = 9.7,   Method: Compositional matrix adjust.
 Identities = 22/86 (25%), Positives = 39/86 (45%), Gaps = 5/86 (5%)
 Frame = +1

Query: 5   LLQGHERSITQIKYNREGDLLF-TVAKDPIVNVW---YSVNGERLGTYMGHTGAVWCVDA 60
           +  GH   +  + ++   + LF +VA D  + +W    +   +       HT  V C+  
Sbjct: 496 IFTGHTSVVEDVAWHLLHESLFGSVADDQKLMIWDTRSNTTSKPSHVVDAHTAEVNCLSF 675

Query: 61  DWDTKHVL-TGSADNSCRLWDCETGK 85
           +  ++ +L TGSAD +  LWD    K
Sbjct: 676 NPYSEFILATGSADKTVALWDLRNLK 753
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|7110693|ref|NP_032880.1| protein kinase, cAMP
dependent, catalytic, alpha [Mus musculus]
         (351 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

03240                                                                 214   6e-56
30755                                                                 170   6e-43
18484                                                                 142   2e-34
27405                                                                 123   1e-28
00486                                                                 120   8e-28
31885                                                                 115   2e-26
15910                                                                 114   6e-26
18921                                                                 112   3e-25
12721                                                                 110   9e-25
09606                                                                 102   3e-22
26560                                                                 101   4e-22
14420                                                                 100   7e-22
01707                                                                  98   5e-21
18663                                                                  97   7e-21
00300                                                                  96   1e-20
13592                                                                  92   2e-19
01392                                                                  92   3e-19
26156                                                                  81   4e-19
17975                                                                  84   9e-17
13066                                                                  84   9e-17
21079                                                                  82   4e-16
06405                                                                  80   1e-15
01060                                                                  80   1e-15
21433                                                                  78   5e-15
17722                                                                  75   4e-14
00392                                                                  73   2e-13
01756                                                                  72   3e-13
27546                                                                  71   7e-13
19094                                                                  69   2e-12
25019                                                                  69   2e-12
19761                                                                  68   4e-12
09007                                                                  68   5e-12
26711                                                                  68   7e-12
11185                                                                  66   3e-11
38560                                                                  65   4e-11
01718                                                                  65   5e-11
29581                                                                  64   6e-11
13212                                                                  64   7e-11
28638                                                                  64   9e-11
28157                                                                  64   1e-10
14126                                                                  62   4e-10
01966                                                                  60   2e-09
21808                                                                  59   2e-09
19301                                                                  59   3e-09
04591                                                                  59   4e-09
04852                                                                  58   5e-09
32957                                                                  57   2e-08
12786                                                                  55   5e-08
07940                                                                  55   6e-08
11780                                                                  54   8e-08
04138                                                                  54   1e-07
00715                                                                  52   3e-07
03508                                                                  52   4e-07
37602                                                                  51   7e-07
20152                                                                  51   8e-07
16708                                                                  49   3e-06
14116                                                                  48   8e-06
27274                                                                  47   1e-05
17300                                                                  46   3e-05
07291                                                                  46   3e-05
17932                                                                  45   4e-05
02638                                                                  45   5e-05
33586                                                                  43   2e-04
18401                                                                  43   2e-04
14477                                                                  42   4e-04
12672                                                                  41   7e-04
31489                                                                  41   9e-04
29590                                                                  40   0.001
26009                                                                  40   0.001
11404                                                                  39   0.003
21800                                                                  39   0.004
37063                                                                  39   0.004
18481                                                                  38   0.005
17516                                                                  38   0.005
20640                                                                  38   0.006
17253                                                                  38   0.006
18996                                                                  37   0.011
01106                                                                  37   0.012
17637                                                                  37   0.012
36481                                                                  37   0.016
06358                                                                  36   0.020
25360                                                                  35   0.040
11089                                                                  35   0.053
21210                                                                  35   0.063
26052                                                                  34   0.075
17591                                                                  33   0.21 
24241                                                                  32   0.39 
28865                                                                  32   0.46 
31120                                                                  32   0.56 
32357                                                                  31   0.78 
00638                                                                  31   0.82 
30339                                                                  30   0.99 
16350                                                                  30   1.4  
06167                                                                  29   3.2  
36002                                                                  29   3.3  
23319                                                                  28   4.5  
17806                                                                  28   5.4  
29360                                                                  28   8.1  
>03240
          Length = 1683

 Score =  214 bits (544), Expect = 6e-56,   Method: Compositional matrix adjust.
 Identities = 127/363 (34%), Positives = 196/363 (53%), Gaps = 58/363 (15%)
 Frame = -3

Query: 39   AQLDQ--FDRIKTLGTGSFGRVMLVKHKESGNHYAMKILDKQKVVKLKQIEHTLNEKRIL 96
            A++D+  F++IKTLG G+FG V L +  ++G  YAMK L K  V+K  Q+ H   E+ IL
Sbjct: 1306 AKMDKCMFEKIKTLGVGAFGEVSLCRKNDTGMLYAMKTLRKSDVLKRNQVAHVKAERDIL 1127

Query: 97   QAVNFPFLVKLEFSFKDNSNLYMVMEYVAGGEMFSHLRRIGRFSEPHARFYAAQIVLTFE 156
               +  ++VKL +SF+D++ LY VM+YV GG++   L R+    EP ARFY A++V   E
Sbjct: 1126 AEADNEWVVKLYYSFQDHNYLYFVMDYVPGGDLMGLLIRMEILDEPLARFYVAELVQAIE 947

Query: 157  YLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWT------------------ 198
             +H +  I+RD+KP+N+LID+ G+I++TDFG      G  WT                  
Sbjct: 946  SVHRMGFIHRDIKPDNILIDRNGHIKLTDFGLC---TGFRWTHNSKYYQRDGTHARQDSM 776

Query: 199  --------------------------------LCGTPEYLAPEIILSK--GYNKAVDWWA 224
                                            L GTP Y+APE +LS+  GY    DWW+
Sbjct: 775  EVKCQLDEQCQCEILKPLERRRKREQRCLAHSLVGTPNYIAPE-VLSRLGGYTSVCDWWS 599

Query: 225  LGVLIYEMAAGYPPFFADQPIQIYEKIVSGK--VRFP--SHFSSDLKDLLRNLLQVDLTK 280
            +GV+++EM  G+PPF+A+ P +   K+++ K  ++ P  S+ S   KDL+  L       
Sbjct: 598  VGVILFEMLVGHPPFYANTPAETQYKVINWKDMLKIPRESNLSQPAKDLILRLC-CGSDD 422

Query: 281  RFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSI 340
            R G   NG  +IK H +FA  ++  +  RK + P++P  +   DTSNFD  + +++R S 
Sbjct: 421  RLG--LNGAGEIKTHMFFAGVNFETL--RKQQPPYVPNIRYATDTSNFDPVDPDKLRNSD 254

Query: 341  NEK 343
            +E+
Sbjct: 253  SEE 245
>30755
          Length = 1137

 Score =  170 bits (431), Expect = 6e-43,   Method: Compositional matrix adjust.
 Identities = 88/218 (40%), Positives = 126/218 (57%), Gaps = 4/218 (1%)
 Frame = +2

Query: 132 HLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKR 191
           HL     F+E   RFY A+I+    YLHS  +IYRDLK ENLL+D+ G+I+V DFG  K 
Sbjct: 2   HLSHERIFTEERTRFYGAEIISALGYLHSQGIIYRDLKLENLLLDKDGHIKVADFGLCKE 181

Query: 192 --VKGRTW-TLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIY 248
               GRT  T CGTPEYLAPE++    Y +AVDWW  GV++YEM  G  PF+      ++
Sbjct: 182 DITYGRTTKTFCGTPEYLAPEVLDDNDYGRAVDWWGTGVVMYEMICGRLPFYNRDHDVLF 361

Query: 249 EKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQ 308
             I+   V+FP + + + K LL  LL  D   R G  ++ V +I+ H +FA+ +W  + Q
Sbjct: 362 TLILVEDVKFPRNITDEAKSLLSGLLAKDPRNRLGGGQDDVKEIQAHPFFASINWTDLVQ 541

Query: 309 RKVEAPFIPKFKGPGDTSNFD-DYEEEEIRVSINEKCG 345
           +K+  PF P+     DT  FD ++  E + ++  +  G
Sbjct: 542 KKITPPFKPQVTSDTDTRYFDEEFTGESVELTPPDPTG 655
>18484
          Length = 635

 Score =  142 bits (358), Expect = 2e-34,   Method: Compositional matrix adjust.
 Identities = 66/159 (41%), Positives = 100/159 (62%), Gaps = 3/159 (1%)
 Frame = +1

Query: 128 EMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFG 187
           ++   +++ G+F EP A FYAA+I +   +LH   +IYRDLK +N+++D +G+I++ DFG
Sbjct: 1   DLMYRIQQEGKFKEPVAAFYAAEIAVGLFFLHDQGIIYRDLKLDNVMLDSEGHIKIADFG 180

Query: 188 FAKRV---KGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQP 244
             K        T T CGTP+Y+APEI+L + Y+K+VDWWA GVL++EM AG PPF  +  
Sbjct: 181 MCKEGMTGDATTRTFCGTPDYIAPEIVLYQPYSKSVDWWAYGVLLFEMLAGQPPFDGEDE 360

Query: 245 IQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFG 283
            +++  I    V +P   S +   L + LL  + TKR G
Sbjct: 361 DELFSSITDHNVSYPKAMSREAVSLCKGLLMKNPTKRLG 477
>27405
          Length = 532

 Score =  123 bits (308), Expect = 1e-28,   Method: Compositional matrix adjust.
 Identities = 63/177 (35%), Positives = 110/177 (62%), Gaps = 7/177 (3%)
 Frame = -3

Query: 54  SFGRVMLVKHKESGNHYAMKILDKQKVVKLKQIEH-TLNEKRILQAVNF----PFLVKLE 108
            FG V   +  ++G  YAMK LDK+++ K+K  E   LNE+ +L  V+     PF+V + 
Sbjct: 530 GFGEVYGCRKADTGKMYAMKCLDKKRI-KMKGGETLALNERIMLSLVSTGEGSPFIVCMT 354

Query: 109 FSFKDNSNLYMVMEYVAGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDL 168
           ++F+    L  +++ + GG++  HL + G F+E   RFYAA+++L  E++HS  ++YRDL
Sbjct: 353 YAFQTPEKLCFILDLMNGGDLHYHLSQHGVFTEKEVRFYAAEVMLGLEHMHSRFVVYRDL 174

Query: 169 KPENLLIDQQGYIQVTDFGFAKRV-KGRTWTLCGTPEYLAPEIIL-SKGYNKAVDWW 223
           KP N+L+D+ G+++++D G A    K +     GT  Y+APE+++  + Y+ + DW+
Sbjct: 173 KPANILLDENGHVRISDLGLACDFSKKKPHASVGTHGYMAPEVLMKGQAYDSSADWF 3
>00486
          Length = 797

 Score =  120 bits (301), Expect = 8e-28,   Method: Compositional matrix adjust.
 Identities = 54/134 (40%), Positives = 82/134 (61%)
 Frame = -2

Query: 196 TWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGK 255
           T T CGT EY+APEI+   G+ KAVDWW+LG L+Y+M  G PPF A+   +  +KI+ GK
Sbjct: 787 THTFCGTIEYMAPEILTRTGHGKAVDWWSLGALMYDMLTGSPPFTAENRKKTIDKILKGK 608

Query: 256 VRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPF 315
           +  P + +++ + L++ LL+ +  +R G   +    IK+H++F  T+W  +  R+ E PF
Sbjct: 607 LNLPPYLTNEARGLIKKLLRKNPAERLGGGHDDSGPIKDHQFFRNTNWALLALRRAEPPF 428

Query: 316 IPKFKGPGDTSNFD 329
            P      DTS FD
Sbjct: 427 RPNVTSDEDTSQFD 386
>31885
          Length = 529

 Score =  115 bits (289), Expect = 2e-26,   Method: Compositional matrix adjust.
 Identities = 56/162 (34%), Positives = 96/162 (59%), Gaps = 7/162 (4%)
 Frame = -2

Query: 95  ILQAVNFPFLVKLEFSFKDNSNLYMVMEYVAGGEMFSHLRRIGRFSEPHARFYAAQIVLT 154
           +L  ++ PFLV L ++F+D  +L+MV++   GG++  H+++   F E   +FY  Q+ L 
Sbjct: 513 MLTRLDHPFLVNLWYAFQDEEDLFMVVDLFLGGDLRYHMQQEVSFREDCVKFYLCQLALV 334

Query: 155 FEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGR--TWTLCGTPEYLAPEII- 211
            +YL S  +++RD+KP+N+L+D+QG+  VTDF  A +++      +  GT  Y+APE+  
Sbjct: 333 LDYLRSQKIVHRDIKPDNILLDEQGHCHVTDFNIATQLEDDELATSTSGTRPYMAPEVYG 154

Query: 212 ----LSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYE 249
                 +GY   VDWW+LGV ++E+     PF       ++E
Sbjct: 153 VAINERRGYGFPVDWWSLGVSLFELLKKRRPFSVHSNTSLHE 28
>15910
          Length = 1361

 Score =  114 bits (285), Expect = 6e-26,   Method: Compositional matrix adjust.
 Identities = 57/164 (34%), Positives = 96/164 (58%), Gaps = 9/164 (5%)
 Frame = +2

Query: 128 EMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLL---IDQQGYIQVT 184
           E+F  +   G+++E  A    + I+   +Y+H+  +++RDLKPENLL   +     +++ 
Sbjct: 422 ELFDRIVTRGQYTEKDAARAISDILHGVQYIHANGVVHRDLKPENLLYECMTDDSKLKLA 601

Query: 185 DFGFAKRVKGRTW--TLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFAD 242
           DFG ++ ++      T+CGTP Y APE++    Y  +VD W++GV+ Y +  GY PFFA+
Sbjct: 602 DFGLSRIIEPEVQMSTVCGTPGYCAPEVLKGDKYTPSVDMWSVGVIAYILLCGYEPFFAE 781

Query: 243 QPIQIYEKIVSGKVRFP----SHFSSDLKDLLRNLLQVDLTKRF 282
              ++Y KI+ G+ +F     S  S + KD++R LL +D  KR 
Sbjct: 782 NEFEMYRKIIKGEYKFDEEYWSEISENAKDVVRKLLVIDPKKRL 913
>18921
          Length = 697

 Score =  112 bits (279), Expect = 3e-25,   Method: Compositional matrix adjust.
 Identities = 67/203 (33%), Positives = 106/203 (52%), Gaps = 4/203 (1%)
 Frame = +2

Query: 42  DQFDRIKTLGTGSFGRVMLVKHKESGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNF 101
           D FD +  LG GS+G V    HKE+G   A+K     +V     ++  + E  I+Q  + 
Sbjct: 29  DVFDILGKLGEGSYGSVFKSLHKETGQVLAIK-----QVPVDTDLQEIIKEISIMQQCDS 193

Query: 102 PFLVKLEFSFKDNSNLYMVMEYVAGGEMFSHLR-RIGRFSEPHARFYAAQIVLTFEYLHS 160
            ++VK   S+  N++L++VMEY   G +   +R R     E          +    YLHS
Sbjct: 194 KYIVKYYGSYFKNTDLWIVMEYCGAGSVSDIMRLRNKTLVEREIATILYYTLKGLXYLHS 373

Query: 161 LDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVK---GRTWTLCGTPEYLAPEIILSKGYN 217
              I+RD+K  N+L++ +G+ ++ DFG A ++     +  T+ GTP ++APE+I   GY+
Sbjct: 374 RRKIHRDIKAGNILLNNEGHAKLADFGVAGQLTDTMAKRNTVIGTPYWMAPEVIQEIGYD 553

Query: 218 KAVDWWALGVLIYEMAAGYPPFF 240
              D W+LG+   EMA G PP  
Sbjct: 554 CVADIWSLGITALEMAEGKPPVM 622
>12721
          Length = 821

 Score =  110 bits (275), Expect = 9e-25,   Method: Compositional matrix adjust.
 Identities = 74/255 (29%), Positives = 129/255 (50%), Gaps = 6/255 (2%)
 Frame = +1

Query: 33  TPSQNTAQLDQFDRIKTLGTGSFGRVMLVKHKESGNHYAMKILDKQKVVKLKQIEHTLNE 92
           TP      LD F +I   G GS G V +   ++ G   A+K +D +K    ++ E   NE
Sbjct: 70  TPGDPRTFLDDFMKI---GEGSTGIVCIATSRD-GRQMAVKKMDLRK---QQRRELLFNE 228

Query: 93  KRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVAGGEMFSHLRRIGRFSEPHARFYAAQIV 152
             +++  + P +V++  S+  N  L++VME++ GG + + +    R  E          +
Sbjct: 229 VVVMRDYHHPNIVEMYNSYLVNDELWVVMEFMEGGAL-TDIVTNNRMDEVQIATVCRACL 405

Query: 153 LTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKG---RTWTLCGTPEYLAPE 209
               +LH+  +I+RD+K +++L+   G +++ DFGF  +V     +  +L GTP ++APE
Sbjct: 406 KALAFLHANGVIHRDIKSDSILLSHDGKVKLXDFGFCAQVTQDLQKRKSLVGTPYWMAPE 585

Query: 210 IILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKI---VSGKVRFPSHFSSDL 266
           +I    Y   VD W+LG+++ EM    PPFF + P+Q   +I      K+R     S  L
Sbjct: 586 VISRLPYGPEVDIWSLGIMVMEMIDAEPPFFNEPPLQAMRRIRDMPPPKLRNTHKISPRL 765

Query: 267 KDLLRNLLQVDLTKR 281
           +  +  +L  D  +R
Sbjct: 766 QGFIDRMLVRDPHQR 810
>09606
          Length = 1300

 Score =  102 bits (253), Expect = 3e-22,   Method: Compositional matrix adjust.
 Identities = 67/277 (24%), Positives = 125/277 (45%), Gaps = 33/277 (11%)
 Frame = -3

Query: 39   AQLDQFDRIKTLGTGSFGRVMLVKHKESGNHYAMKILDKQKVVKLKQIEHTLNEKRILQA 98
             +++ F   + LG G    +   + K + N  A+  ++K K  ++       N  R+   
Sbjct: 1124 TRMENFVLYEELGKGEHSIIYKGRRKGTINFVAIHCIEKCKRPEVT------NTVRMTHD 963

Query: 99   VNFPFLVKLEFSFKDNSNLYMVMEYVAGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYL 158
            ++ P +V+    ++ +++L++V+E   GG +   L +     E   R +   +V    Y+
Sbjct: 962  ISHPNVVQFHEWYETSNHLWLVVELCTGGSLADILAQDHHLPETSIRDFGIHLVTGLHYI 783

Query: 159  HSLDLIYRDLKPENLLIDQQGYIQVTDFGFAK-------------RVKGRTWTL------ 199
            HSL +++ DL+P  +L+D  G ++  DFG +K                G  W +      
Sbjct: 782  HSLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEAGDQWNIQSAEEM 603

Query: 200  ------CGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVS 253
                   G+P Y+APE+      +   D WALG + YEM +G+PPF  +      +K+++
Sbjct: 602  MKQVPTSGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFSGHPPFLGETYDITKDKVLN 423

Query: 254  GKVRFP--------SHFSSDLKDLLRNLLQVDLTKRF 282
             +   P        +  S +  +LL +LLQ D T+R 
Sbjct: 422  KEFPLPKVKGSRLSAKPSPEFLNLLESLLQKDSTRRL 312
>26560
          Length = 398

 Score =  101 bits (252), Expect = 4e-22,   Method: Compositional matrix adjust.
 Identities = 43/114 (37%), Positives = 76/114 (66%), Gaps = 2/114 (1%)
 Frame = -1

Query: 128 EMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFG 187
           ++  HL + G F+E   RFYAA+++L  E++HS  ++YRDLKP N+L+D+ G+++++D G
Sbjct: 398 DLHYHLSQHGVFTEKEVRFYAAEVMLGLEHMHSRFVVYRDLKPANILLDENGHVRISDLG 219

Query: 188 FAKRV-KGRTWTLCGTPEYLAPEIIL-SKGYNKAVDWWALGVLIYEMAAGYPPF 239
            A    K R     GT  Y+APE+++  + Y+ + DW++ G ++Y++  G+ PF
Sbjct: 218 LACDFSKKRPHASVGTHGYMAPEVLMKGQSYDSSADWFSFGCMLYKLLKGHSPF 57
>14420
          Length = 528

 Score =  100 bits (250), Expect = 7e-22,   Method: Compositional matrix adjust.
 Identities = 50/163 (30%), Positives = 89/163 (54%), Gaps = 3/163 (1%)
 Frame = +2

Query: 87  EHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVAGGEMFSHLRRIGRFSEPHARF 146
           E  +NE  +++    P +V    S+     L++VME++AGG +   +       E     
Sbjct: 35  ELIINEILVMRENQNPNIVNYLDSYLVGEELWVVMEFLAGGSLTDVVTETC-MDEGQIAA 211

Query: 147 YAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRV---KGRTWTLCGTP 203
              + +   E+LH   +I+RD+K +N+L+   G +++TDFGF  ++   + +  T+ GTP
Sbjct: 212 VCRECLQALEFLHENQVIHRDIKSDNILLGMDGSVKLTDFGFCAQLSPEQSKRSTMVGTP 391

Query: 204 EYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQ 246
            ++APE++  K Y   VD W+LGV+  EM  G PP+  + P++
Sbjct: 392 YWMAPEVVTRKQYGPTVDIWSLGVMCIEMIEGEPPYLNENPLR 520
>01707
          Length = 757

 Score = 97.8 bits (242), Expect = 5e-21,   Method: Compositional matrix adjust.
 Identities = 62/202 (30%), Positives = 110/202 (54%), Gaps = 6/202 (2%)
 Frame = +1

Query: 40  QLDQFDRIKTLGTGSFGRVMLVKHKESGNHYAMK-ILDKQKVVKLKQIEHTLNEKRILQA 98
           +++++++I  +G GS+G V   ++KE+    A+K  ++ +    +K+I   + E R+L+ 
Sbjct: 58  RMEKYEKIGKIGEGSYGVVFKCRNKETSQLVAIKKFVESEDDPLIKKI--AMREIRMLKQ 231

Query: 99  VNFPFLVKLEFSFKDNSNLYMVMEYVAGGEMFSHLRRIGR-FSEPHARFYAAQIVLTFEY 157
           +  P LV+L   F+    L++V +YV    + + L R  R   EP  +    Q +L   +
Sbjct: 232 LKHPNLVRLIEVFRRKKRLHLVFDYV-DHTLLNELDRYPRGLPEPMVKRIIYQTLLAVNF 408

Query: 158 LHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKG---RTWTLCGTPEYLAPEIILSK 214
            H  + I+RD+KPEN+LI +QG +++ DFGFA+ + G          T  Y APE+++  
Sbjct: 409 CHQYNTIHRDVKPENILITRQGQVKLCDFGFARILTGPGDEYTDYVATRWYRAPELLVGD 588

Query: 215 G-YNKAVDWWALGVLIYEMAAG 235
             Y   VD WA+G +  E+  G
Sbjct: 589 TQYGPPVDVWAIGCVFAELLTG 654
>18663
          Length = 600

 Score = 97.4 bits (241), Expect = 7e-21,   Method: Compositional matrix adjust.
 Identities = 51/141 (36%), Positives = 76/141 (53%), Gaps = 10/141 (7%)
 Frame = +2

Query: 198 TLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPF----FADQPIQ-----IY 248
           T CGTP Y+APEI+  + Y  +VDWWALGVL+YEM AG  PF     ++ P Q     ++
Sbjct: 5   TFCGTPNYIAPEILRGEDYGFSVDWWALGVLLYEMLAGRSPFDIAGASENPDQNTEDYLF 184

Query: 249 EKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFG-NLKNGVNDIKNHKWFATTDWIAIY 307
           + I+   +R P   S     +L+  L  +   R G + ++   DI NH +F   DW  + 
Sbjct: 185 QVILEKTIRIPRSLSVKAASVLKGFLNKNPADRLGCHRESAFMDIVNHPFFKVIDWEMLE 364

Query: 308 QRKVEAPFIPKFKGPGDTSNF 328
           +++V  PF P+     D +NF
Sbjct: 365 RKQVSPPFKPRLDSDRDLANF 427
>00300
          Length = 2318

 Score = 96.3 bits (238), Expect = 1e-20,   Method: Compositional matrix adjust.
 Identities = 71/250 (28%), Positives = 117/250 (46%), Gaps = 11/250 (4%)
 Frame = -1

Query: 43   QFDRIKTLGTGSFGRVMLVKHKESGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFP 102
            ++ R   +G G FG+V    +  +G   A+K +  Q    L+Q+    +E +I + +   
Sbjct: 1655 RWQRGNKIGEGQFGKVYTAVNMSTGELMALKEMKFQPN-DLQQLREMCDEIKIFEGIQHE 1479

Query: 103  FLVKLEFSFKDNSNLYMVMEYVAGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLD 162
             LVK          + M MEY   G +     ++G   E   R Y  +IVL   +LH   
Sbjct: 1478 NLVKYYGVEVHKDEMLMFMEYCDTGTI-EEAAKMG-LPEYLIRRYTREIVLAVNHLHENS 1305

Query: 163  LIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRT------WTLCGTPEYLAPEIILSK-- 214
            +++RD+K  N+ +   G++++ DFG + ++K  T        L GT  Y+APE+      
Sbjct: 1304 IVHRDIKGANIFLTSNGHVKLGDFGCSVKLKSHTTMPGEFHNLVGTTAYMAPEVFTQNDQ 1125

Query: 215  -GYNKAVDWWALGVLIYEMAAGYPPFF-ADQPIQIYEKI-VSGKVRFPSHFSSDLKDLLR 271
             GY +A D W+LG ++ EMA G  P+   D   QI  K+ +  K   P   S + K  L 
Sbjct: 1124 GGYGRAADIWSLGCVVIEMATGKRPWHDLDNNYQIMYKVGIGHKPAVPDSLSVEGKHFLD 945

Query: 272  NLLQVDLTKR 281
             ++  D  +R
Sbjct: 944  LIMCHDPAQR 915
>13592
          Length = 980

 Score = 92.4 bits (228), Expect = 2e-19,   Method: Compositional matrix adjust.
 Identities = 67/249 (26%), Positives = 119/249 (47%), Gaps = 12/249 (4%)
 Frame = +2

Query: 50  LGTGSFGRVMLVKHKESGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEF 109
           +G G FG+V    +  +G   AMK +  Q   + + +++   E +IL+ +    LV+   
Sbjct: 8   IGQGRFGKVYTAVNNNTGELMAMKEIAIQPG-ETRALKNVAEELKILEGIKHKNLVRYYG 184

Query: 110 SFKDNSNLYMVMEYVAGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLK 169
                  L + ME  + G + S +   G   E  +R + AQ++     LH   +++RD+K
Sbjct: 185 IEVHREELLIFMELCSEGTLESLVELTGGLPEALSRRFTAQLLSGVAELHKHGIVHRDIK 364

Query: 170 PENL-LIDQQGYIQVTDFGFAKRVKGRTWT------LCGTPEYLAPEIIL---SKGYNKA 219
             N+ L+D    +++ DFG A +++  T          GT  Y+APE+     S G+ + 
Sbjct: 365 TANIFLVDGSNSLKLGDFGSAVKIQAHTTVPGELQGYVGTQAYMAPEVFTKTNSDGHGRL 544

Query: 220 VDWWALGVLIYEMAAGYPPFFA-DQPIQIYEKIVSG-KVRFPSHFSSDLKDLLRNLLQVD 277
            D W++G ++ EMA+G  P+   D   QI  K+  G K + P   S +  D + + LQ D
Sbjct: 545 ADIWSVGCVVVEMASGKRPWAQFDSNFQIMFKVGMGEKPQAPESLSQEGHDFIDHCLQHD 724

Query: 278 LTKRFGNLK 286
             +R   ++
Sbjct: 725 PKQRLSAIE 751
>01392
          Length = 1806

 Score = 92.0 bits (227), Expect = 3e-19,   Method: Compositional matrix adjust.
 Identities = 60/199 (30%), Positives = 88/199 (44%), Gaps = 35/199 (17%)
 Frame = -1

Query: 137  GRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLL---IDQQGYIQVTDFGFAKRVK 193
            G   E  A      I    ++LHS  + +RDLKPEN+L   +D    +++ DF  A  + 
Sbjct: 1806 GHLCEREASLVVRHIARALDFLHSKGIAHRDLKPENILCEHLDDVVPVKICDFDLASGIS 1627

Query: 194  G--------RTWTLCGTPEYLAPEIIL-----SKGYNKAVDWWALGVLIYEMAAGYPPFF 240
                        T  G+ EY+APE++      S  Y+K  D W+LG+++Y M  GYPPF+
Sbjct: 1626 CDGDGTKTPELLTPVGSAEYMAPEVVDAWVGDSFSYDKRCDLWSLGIILYIMLCGYPPFY 1447

Query: 241  A---------------DQPIQIYEKIVSGKVRFPSH----FSSDLKDLLRNLLQVDLTKR 281
                            D    ++  I  G  +FPS      SS  KDL+R+LL  +  KR
Sbjct: 1446 GQCGEDCGWNRGEACHDCQDMLFNSIQDGHYKFPSQEWTSISSSAKDLIRHLLVREPRKR 1267

Query: 282  FGNLKNGVNDIKNHKWFAT 300
            +        D+  H W  T
Sbjct: 1266 Y-----SAADVLKHPWICT 1225
>26156
          Length = 479

 Score = 80.9 bits (198), Expect(2) = 4e-19,   Method: Compositional matrix adjust.
 Identities = 42/112 (37%), Positives = 67/112 (59%), Gaps = 1/112 (0%)
 Frame = -1

Query: 36  QNTAQLDQFDRIKTLGTGSFGRVMLVKHKESGNHYAMKILDKQKVVKLKQIEHTLNEKRI 95
           +N   L  F  ++ +G GS+ +V+ V+HK +   YAMK++ K+ V   + I+    EK +
Sbjct: 407 RNKLGLTDFLLLRVIGRGSYAKVLQVEHKRTKRIYAMKVIKKELVNDDEDIDWVQTEKHV 228

Query: 96  LQ-AVNFPFLVKLEFSFKDNSNLYMVMEYVAGGEMFSHLRRIGRFSEPHARF 146
            + A N+PFLV L   F+  S L+ V+E+V GG++  H++R  R  E HARF
Sbjct: 227 FETATNYPFLVGLHSCFQSESRLFFVIEFVNGGDLMFHMQRQRRLPEEHARF 72

 Score = 31.2 bits (69), Expect(2) = 4e-19,   Method: Compositional matrix adjust.
 Identities = 12/24 (50%), Positives = 17/24 (70%)
 Frame = -3

Query: 146 FYAAQIVLTFEYLHSLDLIYRDLK 169
           FY+A+I L   +LH   ++YRDLK
Sbjct: 75  FYSAEICLALNFLHKRGIVYRDLK 4
>17975
          Length = 449

 Score = 84.0 bits (206), Expect = 9e-17,   Method: Compositional matrix adjust.
 Identities = 47/137 (34%), Positives = 80/137 (58%), Gaps = 2/137 (1%)
 Frame = +3

Query: 55  FGRVMLVKHKESGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDN 114
           F  V L +H  +G   A+K++DK K+ ++ +  H   E R ++ V  P +V+L       
Sbjct: 6   FAVVKLARHVFTGEKVAVKVIDKTKLDEVSR-SHLFQEVRCMKLVQHPNVVRLYEVIDTQ 182

Query: 115 SNLYMVMEYVAGGEMFSH-LRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENL 173
           + LY+++E   GG+M+ + +R  G   E  A+ Y  QIV    Y H L +++RDLKPEN+
Sbjct: 183 TKLYLILELGDGGDMYDYIMRHSGGLEEKLAKRYFRQIVEAISYCHKLHVVHRDLKPENV 362

Query: 174 L-IDQQGYIQVTDFGFA 189
           +  ++ G +++TDFGF+
Sbjct: 363 VFFEKPGLVKLTDFGFS 413
>13066
          Length = 551

 Score = 84.0 bits (206), Expect = 9e-17,   Method: Compositional matrix adjust.
 Identities = 48/164 (29%), Positives = 85/164 (51%), Gaps = 8/164 (4%)
 Frame = +3

Query: 71  AMKILDKQKVVKLKQIEHTL-NEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVAGGEM 129
           A KI+DK+K   +  +E     E  +L  ++ P+++++    +     ++ M +   G++
Sbjct: 63  ACKIIDKEKA-PVDFVEKFFPRELDLLTKLDHPYIIQIHSILQRXPKNFIFMRFAERGDL 239

Query: 130 FSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFA 189
            ++++ +G   E  A+ +  Q+     YLHS D+ +RDLK EN+L+     +++ DFGFA
Sbjct: 240 LTYIQEVGFVKEKQAKIWFYQMTTALNYLHSYDVAHRDLKCENILLSSHFNVKLADFGFA 419

Query: 190 KRV------KGRTWTLCGTPEYLAPEIILSKGYN-KAVDWWALG 226
                    K  + T CG+  Y APEI+    Y  K  D W+LG
Sbjct: 420 CACITESGEKYMSRTYCGSAAYAAPEIVYGAPYAPKVADAWSLG 551
>21079
          Length = 878

 Score = 81.6 bits (200), Expect = 4e-16,   Method: Compositional matrix adjust.
 Identities = 47/142 (33%), Positives = 75/142 (52%), Gaps = 5/142 (3%)
 Frame = +1

Query: 102 PFLVKLEFSFKDNSNLYMVMEYVAGGEMFSHLRRIG-RFSEPHARFYAAQIVLTFEYLHS 160
           P L+ L  +F+    + +VME+V  GE+F  + R     +E     +  QI     Y+H+
Sbjct: 4   PKLLMLWDAFEAPRTMVLVMEFVGAGELFERVIRDDFVLTERDCVHFVRQICSGVGYMHT 183

Query: 161 LDLIYRDLKPENLLI--DQQGYIQVTDFGFAKRVK--GRTWTLCGTPEYLAPEIILSKGY 216
             +++ DLKPEN+L   D    I++ DFG A+  K       L GTPE++APE++     
Sbjct: 184 QSILHLDLKPENVLCVSDNSNQIKIIDFGLARFYKPGDSLQVLFGTPEFIAPEVVNYDEI 363

Query: 217 NKAVDWWALGVLIYEMAAGYPP 238
           N   D W++GV+ Y + +G  P
Sbjct: 364 NFTTDMWSIGVICYILLSGLSP 429
>06405
          Length = 1965

 Score = 80.5 bits (197), Expect = 1e-15,   Method: Compositional matrix adjust.
 Identities = 69/240 (28%), Positives = 109/240 (45%), Gaps = 8/240 (3%)
 Frame = +1

Query: 50  LGTGSFGRVMLVKHKESGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEF 109
           LG G +G V     K      A+K L K+  + L      L E  I++ +  P LV+L  
Sbjct: 283 LGGGQYGDVYEAMWKRYNKIVAVKTL-KEDTMALNDF---LEEAAIMKEMKHPNLVQLLG 450

Query: 110 SFKDNSNLYMVMEYVAGGEMFSHLRRIGRFSE-PHARFY-AAQIVLTFEYLHSLDLIYRD 167
                   Y+V E++  G +  +LR   R    P A  Y A QI     YL + + I+RD
Sbjct: 451 VCTREPPFYIVTEFMPHGNLLDYLRSSTREENGPTALMYMATQIASGMAYLETKNFIHRD 630

Query: 168 LKPENLLIDQQGYIQVTDFGFAKRVKGRTWTL-CGTP---EYLAPEIILSKGYNKAVDWW 223
           L   N L+     ++V DFG A+ +K  T+T   G     ++ APE +    ++   D W
Sbjct: 631 LAARNCLVADSNMVKVADFGLARLMKDDTYTAHIGAKFPIKWTAPEGLAFNRFSTRSDIW 810

Query: 224 ALGVLIYEMAA-GYPPFFADQPIQIYEKIVSG-KVRFPSHFSSDLKDLLRNLLQVDLTKR 281
           A GVL++E+A  G  P+   +  ++Y  +  G ++  P    +D+  L+    Q D   R
Sbjct: 811 AFGVLLWELATYGMSPYPGVELTEVYHLLERGYRMERPPGTPADVYILMLKCWQWDPKDR 990
>01060
          Length = 1800

 Score = 80.5 bits (197), Expect = 1e-15,   Method: Compositional matrix adjust.
 Identities = 64/219 (29%), Positives = 107/219 (48%), Gaps = 17/219 (7%)
 Frame = +1

Query: 50  LGTGSFGRVMLVKHKESGNHYAMKILDKQKVVKLKQIE-----HTLNEKRILQAVNFPFL 104
           +G G++G V   +H+ +G   AMK       ++L+  E       + E  +L+ +    +
Sbjct: 97  IGEGTYGVVYKCRHRATGRKLAMK------KIRLRGSEDGVPSSAIREIAMLRELRHTNI 258

Query: 105 VKLEFSFKDNSNLYMVMEYVAGG-EMFSHLRRIGRFSE------PHARFYAAQIVLTFEY 157
           V LE    ++  L++V E+++   +M+     I +F E         + Y  QIV    +
Sbjct: 259 VCLEDVIMEDERLFLVFEFLSMDLKMY-----IDKFPEGVVLDRRLVKSYVFQIVTGIXF 423

Query: 158 LHSLDLIYRDLKPENLLIDQQGYIQVTDFG----FAKRVKGRTWTLCGTPEYLAPEIIL- 212
            H   +++RDLKP+NLLI+  G I++ DFG    FA  V+  T  +  T  Y APEI++ 
Sbjct: 424 CHQRRIVHRDLKPQNLLINHTGAIKIADFGMARTFALPVRAYTHEVV-TLWYRAPEILMG 600

Query: 213 SKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKI 251
           +  Y+  VD W++G +  +M    P F  D  I    KI
Sbjct: 601 ASKYSTPVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKI 717
>21433
          Length = 590

 Score = 78.2 bits (191), Expect = 5e-15,   Method: Compositional matrix adjust.
 Identities = 46/130 (35%), Positives = 69/130 (53%), Gaps = 1/130 (0%)
 Frame = +2

Query: 147 YAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRV-KGRTWTLCGTPEY 205
           Y  Q+    EY H   +I+RD+KPENLL+  +G +++ DFG++      R  T+CGT +Y
Sbjct: 182 YIYQLSSALEYCHYRKVIHRDIKPENLLLGLKGDLKIADFGWSVHAPSSRRTTMCGTLDY 361

Query: 206 LAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSD 265
           L PE++  K +++ VD W+LGVL YE   G PP                    PS  +  
Sbjct: 362 LPPEMVEGKTHDENVDLWSLGVLCYEFLVGTPPLRPSPTRPPTPASPRWTSGSPSIVTPG 541

Query: 266 LKDLLRNLLQ 275
            +DL+  LL+
Sbjct: 542 ARDLISKLLR 571
>17722
          Length = 680

 Score = 75.1 bits (183), Expect = 4e-14,   Method: Compositional matrix adjust.
 Identities = 37/106 (34%), Positives = 56/106 (52%)
 Frame = -3

Query: 220 VDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLT 279
           VDWW  GV++YEM  G  PF+      ++E I+   V+FP + S + K LL  LL  +  
Sbjct: 678 VDWWGTGVVMYEMMCGRLPFYNRDHDVLFELILLQNVKFPRNLSEEAKTLLSGLLAKNPK 499

Query: 280 KRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDT 325
           +R G  +  V +IK H +F   +W  +  +K+  P+ P  K   DT
Sbjct: 498 RRLGGSEADVTEIKTHPFFQCINWDDLAAKKITPPWKPDVKSSWDT 361
>00392
          Length = 668

 Score = 73.2 bits (178), Expect = 2e-13,   Method: Compositional matrix adjust.
 Identities = 50/177 (28%), Positives = 99/177 (55%), Gaps = 14/177 (7%)
 Frame = +3

Query: 92  EKRILQAVNFPFLVKL-----EFSFKDNSNLYMVMEYVAGGEMFSHLRRIGRFSEPHARF 146
           E  +L+ +  P +V+      E + ++   + +V E +  G + ++L+R   F +P+ + 
Sbjct: 81  EAEMLKELQHPNIVRFFDYWEEHNHRNRKVIILVTELMTSGTLKTYLKR---FKKPNVKI 251

Query: 147 ---YAAQIVLTFEYLHSLD--LIYRDLKPENLLID-QQGYIQVTDFGFAKRVKGRTW--T 198
              +  Q++    +LH+    +I+RDLK +N+ I    G +++ D G A  +K +++  +
Sbjct: 252 LKNWCRQVLKGLYFLHTRTPPVIHRDLKCDNIFITGPTGSVKIGDLGLAT-LKNQSFAKS 428

Query: 199 LCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAG-YPPFFADQPIQIYEKIVSG 254
           + GTPE++APE+   + Y++AVD +A G+ + EMA+  YP        QIY+++ SG
Sbjct: 429 VIGTPEFMAPEM-YEEHYDEAVDVYAFGMCMLEMASSEYPYSECSNAAQIYKRVTSG 596
>01756
          Length = 1858

 Score = 72.0 bits (175), Expect = 3e-13,   Method: Compositional matrix adjust.
 Identities = 55/214 (25%), Positives = 107/214 (50%), Gaps = 19/214 (8%)
 Frame = -3

Query: 43   QFDRIKTLGTGSFGRVMLVKHKESGNHYAMK--ILDKQK----VVKLKQIE--HTLNEKR 94
            +++++  +G G+FG V   + K++    AMK  ++D +K    +  L++I+    LN + 
Sbjct: 1739 KYEKLAKIGQGTFGEVFKARCKKTKQVVAMKKVLMDNEKEGFPITALREIKILQLLNHEN 1560

Query: 95   ILQAVNFPFLVKLEFSFKDNSNLYMVMEY----VAGGEMFSHLRRIGRFSEPHARFYAAQ 150
            ++  +      K   + +  S  Y+V E+    +AG  + S++  +  F+ P  +    Q
Sbjct: 1559 VVDLIEI-CSTKATSANRYKSMFYLVFEFCEHDLAG--LLSNMSVV--FNLPEIKEVMKQ 1395

Query: 151  IVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAK------RVKGRTWTLCGTPE 204
            ++    Y+H   +++RD+K  N+LI +QG +++ DFG A+      R   R      T  
Sbjct: 1394 LMNGLYYIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRVVTLW 1215

Query: 205  YLAPEIILS-KGYNKAVDWWALGVLIYEMAAGYP 237
            Y  PE++L  + Y+ A+D W  G ++ EM    P
Sbjct: 1214 YRPPELLLGDRNYSTAIDQWGAGCIMAEMWTRNP 1113
>27546
          Length = 426

 Score = 70.9 bits (172), Expect = 7e-13,   Method: Compositional matrix adjust.
 Identities = 30/102 (29%), Positives = 59/102 (57%)
 Frame = -1

Query: 92  EKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVAGGEMFSHLRRIGRFSEPHARFYAAQI 151
           E  IL  ++ P ++++    +    +++ M Y   G+M SH+++ G   E   + +  Q+
Sbjct: 330 ELEILTRLDHPNIIQIHSILQRGPKIFIFMRYAEKGDMLSHIKKTGPIDEAQTKVWFFQM 151

Query: 152 VLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVK 193
               +YLHS D+ +RDLK EN+L+ ++  +++ DFGFA+  +
Sbjct: 150 AKALQYLHSHDIAHRDLKCENILLSKRLNVKIADFGFARYCR 25
>19094
          Length = 898

 Score = 69.3 bits (168), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 33/82 (40%), Positives = 52/82 (63%), Gaps = 3/82 (3%)
 Frame = +1

Query: 157 YLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVK---GRTWTLCGTPEYLAPEIILS 213
           YLHS   I+RD+K  N+L++ +G+ ++ DFG A ++     +  T+ GTP ++APE+I  
Sbjct: 103 YLHSRRKIHRDIKAGNILLNNEGHAKLADFGVAGQLTDTMAKRNTVIGTPYWMAPEVIQE 282

Query: 214 KGYNKAVDWWALGVLIYEMAAG 235
            GY+   D W+LG+   EMA G
Sbjct: 283 IGYDCVADIWSLGITALEMAEG 348
>25019
          Length = 730

 Score = 69.3 bits (168), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 31/59 (52%), Positives = 43/59 (72%), Gaps = 3/59 (5%)
 Frame = +3

Query: 171 ENLLIDQQGYIQVTDFGFAKR-VKGR--TWTLCGTPEYLAPEIILSKGYNKAVDWWALG 226
           EN+L+D+ G++++TDFG  K  + G   T T CGT EY+APEI+   G+ KAVDWW+LG
Sbjct: 261 ENVLLDKDGHVKLTDFGLCKEAITGTRVTHTFCGTIEYMAPEILTRTGHGKAVDWWSLG 437

 Score = 47.8 bits (112), Expect = 7e-06,   Method: Compositional matrix adjust.
 Identities = 23/74 (31%), Positives = 41/74 (55%), Gaps = 4/74 (5%)
 Frame = +1

Query: 214 KGYNKAVDW----WALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDL 269
           +G   A  W    W  G L+Y+M  G PPF A+   +  +KI+ GK+  P + +++ + L
Sbjct: 394 RGQGTARRWTGGVW--GALMYDMLTGSPPFTAENRKKTIDKILKGKLNLPPYLTNEARGL 567

Query: 270 LRNLLQVDLTKRFG 283
           ++ LL+ +  +R G
Sbjct: 568 IKKLLRKNPAERLG 609
>19761
          Length = 473

 Score = 68.2 bits (165), Expect = 4e-12,   Method: Compositional matrix adjust.
 Identities = 34/128 (26%), Positives = 68/128 (53%), Gaps = 3/128 (2%)
 Frame = -3

Query: 153 LTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGR---TWTLCGTPEYLAPE 209
           L + + H+  +++RDLKP+N+ + ++G +++ D G A+++ G      +  GT  YL+PE
Sbjct: 384 LNYMHTHTPVILHRDLKPQNIYVTEKGDVRLGDLGLARKLTGPADFATSQVGTIMYLSPE 205

Query: 210 IILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDL 269
           I+  + YN   D W+LG + Y++              + + +   K+  P H+S + +D 
Sbjct: 204 ILSQQPYNSKSDIWSLGCVFYDITGKKGSDEMGVMFLLVQVMGGRKLPLPDHYSQEFRDT 25

Query: 270 LRNLLQVD 277
           +  +L  D
Sbjct: 24  ISRMLTKD 1
>09007
          Length = 1440

 Score = 68.2 bits (165), Expect = 5e-12,   Method: Compositional matrix adjust.
 Identities = 59/220 (26%), Positives = 101/220 (45%), Gaps = 16/220 (7%)
 Frame = -1

Query: 48  KTLGTGSFGRV-MLVKHKESGN--HYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFL 104
           K+LG G FG V   +   ESG     A+K L K K+ K  Q    L E  I+Q ++   +
Sbjct: 861 KSLGQGHFGTVRQAIWTAESGEKVQVAVKCLSKDKIHKDGQ--EFLKETAIMQMLDHENI 688

Query: 105 VKLEFSFKDN-SNLYMVMEYVAGGEMFSHLRRIGR---FSEPHARFYAAQIVLTFEYLHS 160
           V++     DN +++ +V E      +   ++ +     FS P    ++ Q+     YL S
Sbjct: 687 VRVYGVVMDNGADIMLVTELAPMRSLLECVKEVSARVDFSVPRLCDFSQQVCDGMSYLES 508

Query: 161 LDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKG--------RTWTLCGTPEYLAPEIIL 212
             L++RDL   N+L+  +  ++++D G +  +          +T  L     + APE   
Sbjct: 507 KRLVHRDLAARNILLFSKSKVKISDVGVSGALGAGKEYYQSQQTIHLQNAVAWCAPESFR 328

Query: 213 SKGYNKAVDWWALGVLIYE-MAAGYPPFFADQPIQIYEKI 251
           +  ++ A D WA GVL++E    G+ P+      QI E +
Sbjct: 327 NLCFSSASDVWAFGVLLWEFFTHGFQPWAGLNGQQIMEAV 208
>26711
          Length = 405

 Score = 67.8 bits (164), Expect = 7e-12,   Method: Compositional matrix adjust.
 Identities = 41/130 (31%), Positives = 70/130 (53%), Gaps = 9/130 (6%)
 Frame = -2

Query: 150 QIVLTFEYLHSLDLIYRDLKPENLLI--DQQGYIQVTDFGFAKRV--KGRTWTLCGTPEY 205
           Q++   +++H+  +++ DLKP NLL+  D+   +Q+ DFG A+++     T+   GTP +
Sbjct: 392 QVLDILQHVHAQGVVHMDLKPSNLLLSGDKLDSVQLIDFGLARKLYPPQETFLNHGTPGF 213

Query: 206 LAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFP-----S 260
            +PE +  K  + A D W +GVL Y + +G  PF AD   +  +K  +    F      S
Sbjct: 212 TSPEALDVKPISTASDVWGVGVLAYILLSGQSPFQADSATESLKKTQTCDWSFDVCPSFS 33

Query: 261 HFSSDLKDLL 270
           + S D KD +
Sbjct: 32  NMSQDAKDFI 3
>11185
          Length = 473

 Score = 65.9 bits (159), Expect = 3e-11,   Method: Compositional matrix adjust.
 Identities = 43/163 (26%), Positives = 67/163 (41%), Gaps = 25/163 (15%)
 Frame = +1

Query: 145 RFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAK-------------R 191
           R +   +V    Y+HSL +++ DL+P  +L+D  G ++  DFG +K              
Sbjct: 10  RDFGIHLVTGLHYIHSLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFA 189

Query: 192 VKGRTWTL------------CGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPF 239
             G  W +             G+P Y+APE+      +   D WALG + YEM +G    
Sbjct: 190 EAGDQWNIQSAEEMMKQVPTSGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFSG---- 357

Query: 240 FADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRF 282
                            R  +  S +  +LL +LLQ D T+R 
Sbjct: 358 ----------------SRLSAKPSPEFLNLLESLLQKDSTRRL 438
>38560
          Length = 479

 Score = 65.1 bits (157), Expect = 4e-11,   Method: Compositional matrix adjust.
 Identities = 38/131 (29%), Positives = 60/131 (45%), Gaps = 6/131 (4%)
 Frame = -3

Query: 198 TLCGTPEYLAPEIILSKGY-NKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKV 256
           T CG+P Y APE+I    Y     D W++GVL+Y +  GY PF  ++   + +K    K 
Sbjct: 408 TCCGSPAYAAPELISGLEYLGSEADIWSMGVLLYALLCGYLPFDDEKXSHL*QKNQKRKD 229

Query: 257 RFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWF-----ATTDWIAIYQRKV 311
             P   S D   LL  +LQ D + R       +  + +H W         +W + Y+R +
Sbjct: 228 EVPEWLSEDTTKLLEGMLQTDPSHRI-----TIRRLLDHHWLNQGFNVPVEWASKYKRTL 64

Query: 312 EAPFIPKFKGP 322
           +   + +  GP
Sbjct: 63  DEDCLTEAGGP 31
>01718
          Length = 959

 Score = 64.7 bits (156), Expect = 5e-11,   Method: Compositional matrix adjust.
 Identities = 56/214 (26%), Positives = 99/214 (46%), Gaps = 15/214 (7%)
 Frame = +3

Query: 39  AQLDQFDRIKTLGTGSFGRVMLVKHKESGNHYAMKILDKQKVVKLKQIEHTLNEKRILQA 98
            +LD F   + +G G F  V  V H+ +G   A+K+             + L E ++L  
Sbjct: 141 TRLDDFI-CEKIGAGFFSEVFKVTHRITGQVMALKM-----NTMTSNRHNMLREVQLLNR 302

Query: 99  VNFPFLVKLEFSFKDNSNLYMVMEYVAGGEMFSHLRRIGRFSEPHARFYAAQIVLTF--- 155
           +    +++          L+ + EY+  G +   L +     +     +  +I LT    
Sbjct: 303 LQHANILRFMGVCVHEGQLHALTEYIPSGNLEQLLEK-----KDEELPWTQRIQLTLGLA 467

Query: 156 ---EYLHSLDLIYRDLKPENLLI---DQQGYIQV-TDFGFAKRV-----KGRTWTLCGTP 203
              +YLHS   I+RDL  +N+LI   D  GY  V  DFG A ++     K +  T+ G+P
Sbjct: 468 RGLDYLHSTRFIHRDLTSKNILIRREDNHGYHAVIADFGLATKIPDPLDKEKLPTV-GSP 644

Query: 204 EYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYP 237
            ++APE++    YN+  D +++G+++ E+ A  P
Sbjct: 645 YWMAPEVLNGHFYNERADLFSVGIIMCEITARIP 746
>29581
          Length = 1278

 Score = 64.3 bits (155), Expect = 6e-11,   Method: Compositional matrix adjust.
 Identities = 42/133 (31%), Positives = 70/133 (52%), Gaps = 7/133 (5%)
 Frame = -2

Query: 112  KDNSNLYMVMEYVAGGEMFSHLRRI-GRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKP 170
            K   +L++VMEY    ++ S L  +   FSE   +    Q++    YLH   +I+RDLK 
Sbjct: 1139 KSLDSLFLVMEYCEQ-DLASLLDNMPAPFSESQVKCIVLQLLKGLRYLHEAFIIHRDLKV 963

Query: 171  ENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPE-----YLAPEIIL-SKGYNKAVDWWA 224
             NLL+  +G +++ DFG A+        +  TP+     Y APE++  SK ++ A+D W+
Sbjct: 962  SNLLMTDKGCVKIADFGLARNYGKPQKPM--TPKVVTLWYRAPELLFGSKTHSTAIDMWS 789

Query: 225  LGVLIYEMAAGYP 237
             G ++ E+    P
Sbjct: 788  AGCILGELLGHKP 750
>13212
          Length = 1067

 Score = 64.3 bits (155), Expect = 7e-11,   Method: Compositional matrix adjust.
 Identities = 34/121 (28%), Positives = 64/121 (52%), Gaps = 8/121 (6%)
 Frame = -1

Query: 139 FSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKR---VKGR 195
            +E    +   ++ +  ++LH   +I+RD+K  N+L+   G +++ DFG + +    + +
Sbjct: 989 MTEAQICYVCHEMCMALDFLHRHHVIHRDIKAGNVLLTIDGEVKLADFGVSAKNTQTQQK 810

Query: 196 TWTLCGTPEYLAPEIILSK-----GYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEK 250
             T  GTP ++APE++L +      Y+   D W+LGV + E A   PP     P+++  K
Sbjct: 809 RDTFIGTPYWMAPEVVLCETLKDTPYDFKADIWSLGVTLIEFAQIEPPNKEMHPMRVLIK 630

Query: 251 I 251
           I
Sbjct: 629 I 627
>28638
          Length = 1458

 Score = 63.9 bits (154), Expect = 9e-11,   Method: Compositional matrix adjust.
 Identities = 32/100 (32%), Positives = 59/100 (59%), Gaps = 4/100 (4%)
 Frame = -1

Query: 144 ARFYAAQIVLTFEYLHS--LDLIYRDLKPENLLI--DQQGYIQVTDFGFAKRVKGRTWTL 199
            R +A Q+     +L +  +++I+ DLKPEN+L+   ++  I++ DFG + ++  R +  
Sbjct: 831 TRKFAQQLCTALLFLATPEMNIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQY 652

Query: 200 CGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPF 239
             +  Y +PE++L   Y+ A+D W+LG ++ EM  G PP 
Sbjct: 651 IQSRFYRSPEVLLGVPYDLAIDMWSLGCILVEMHTGEPPL 532
>28157
          Length = 400

 Score = 63.5 bits (153), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 44/124 (35%), Positives = 68/124 (54%), Gaps = 13/124 (10%)
 Frame = +3

Query: 79  KVVKLKQIEHTLNEKRILQA------VNFPFLVKLEFSFKDNSNLYMVMEYVAGGEMFSH 132
           K V +K+IE    +K  +Q       V+ P +V L  + +D+  + +VMEY  GG +++ 
Sbjct: 3   KDVAVKRIESEQEKKSFMQELKQLSRVSHPNIVCLYGACRDHP-VCLVMEYAEGGSLYNV 179

Query: 133 LRRIG---RFSEPHARFYAAQIVLTFEYLHSLD---LIYRDLKPENLLIDQQGY-IQVTD 185
           L   G   +++  HA  +  Q  L  EYLH +    LI+RDLKP NLL+ Q G  +++ D
Sbjct: 180 LHGSGPQPQYTAAHAMNWLLQCALGVEYLHGMKPKALIHRDLKPPNLLLIQCGTKLKICD 359

Query: 186 FGFA 189
           FG A
Sbjct: 360 FGTA 371
>14126
          Length = 1265

 Score = 62.0 bits (149), Expect = 4e-10,   Method: Compositional matrix adjust.
 Identities = 29/85 (34%), Positives = 51/85 (60%), Gaps = 2/85 (2%)
 Frame = +3

Query: 150 QIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAK--RVKGRTWTLCGTPEYLA 207
           Q++   ++LHS  +++RDLKP+NLLI + G +++ DFG A+         T+  T  Y +
Sbjct: 540 QLLNGVDFLHSNRIVHRDLKPQNLLISKDGRLKLADFGLARIYSFHMALTTVVVTLWYRS 719

Query: 208 PEIILSKGYNKAVDWWALGVLIYEM 232
           PE+++   Y  +VD W+ G +  E+
Sbjct: 720 PEVLMQAEYGTSVDIWSCGCIFAEL 794
>01966
          Length = 1735

 Score = 59.7 bits (143), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 52/184 (28%), Positives = 86/184 (46%), Gaps = 16/184 (8%)
 Frame = -1

Query: 61   VKHKESGNHYAMKILDKQKVVKLKQIE-----HTLNEKRILQAVNFPFLVKLEFSFKDNS 115
             +H+ +G   AMK       ++L+  E       + E  +L+ +    +V LE    ++ 
Sbjct: 1654 CRHRATGRKLAMK------KIRLRGSEDGVPSSAIREIAMLRELRHTNIVCLEDVIMEDE 1493

Query: 116  NLYMVMEYVAGG-EMFSHLRRIGRFSE------PHARFYAAQIVLTFEYLHSLDLIYRDL 168
             L++V E+++   +M+     I +F E         + Y  QIV    + H   +++RDL
Sbjct: 1492 RLFLVFEFLSMDLKMY-----IDKFPEGVVLDRRLVKSYVFQIVTGINFCHQRRIVHRDL 1328

Query: 169  KPENLLIDQQGYIQVTDFG----FAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWA 224
            KP+NLLI+  G I++ DFG    FA  V+  T  +  T  Y APEI++  G       W 
Sbjct: 1327 KPQNLLINHTGAIKIADFGMARTFALPVRAYTHEVV-TLWYRAPEILM--GPQSTPPXWT 1157

Query: 225  LGVL 228
             G L
Sbjct: 1156 CGAL 1145
>21808
          Length = 1011

 Score = 59.3 bits (142), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 44/192 (22%), Positives = 85/192 (44%), Gaps = 11/192 (5%)
 Frame = +1

Query: 90  LNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVAGGEMFSHLRRIGRFSE-PHARFYA 148
           L E +I++ +  P L++L      +  ++++ E +  G +   L+  GR  + P      
Sbjct: 76  LAEAQIMKKLRHPKLIQLYAVCTQDDPIFIITELMKNGSLLEFLQGKGRVLKLPALIDIG 255

Query: 149 AQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVK--------GRTWTLC 200
           AQI     YL S + I+RDL   N+L+     +++ DFG A+ +K        G  + + 
Sbjct: 256 AQIACGMAYLESQNYIHRDLAARNILVSDNNTVKIADFGLARVIKEDEYEARVGARFPI- 432

Query: 201 GTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAA-GYPPFFADQPIQIYEKIVSG-KVRF 258
              ++ APE      +    D W+ G+L+ E    G  P+      ++  ++  G ++  
Sbjct: 433 ---KWTAPEAANYNRFTIKSDVWSFGILLTETVTYGRVPYPGMTNAEVLHQVEHGYRMPC 603

Query: 259 PSHFSSDLKDLL 270
           P      L D++
Sbjct: 604 PPGCPKPLYDIM 639
>19301
          Length = 712

 Score = 58.9 bits (141), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 45/172 (26%), Positives = 79/172 (45%), Gaps = 3/172 (1%)
 Frame = +2

Query: 19  FLAKAKEDFLKK---WETPSQNTAQLDQFDRIKTLGTGSFGRVMLVKHKESGNHYAMKIL 75
            + KA    LK+   WE P ++   L+       LG+G+ G V L K             
Sbjct: 245 IIGKAAAAELKQQDDWEIPFESITDLEW------LGSGAQGAVFLGK----------LCA 376

Query: 76  DKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVAGGEMFSHLRR 135
           ++  V K++ I+ T  + R L+ +N P ++  +          ++MEY   G+++  LR 
Sbjct: 377 EEVAVKKVRDIKET--DIRNLRKLNHPNIISFKGVCTQAPCYCIIMEYCPYGQLYEVLRD 550

Query: 136 IGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFG 187
                      ++ QI     YLHS  +I+RDLK  N+L+ +   ++++DFG
Sbjct: 551 GKEIPPALVLDWSKQIASGMNYLHSHKIIHRDLKSPNVLVAKNDVVKISDFG 706
>04591
          Length = 1117

 Score = 58.5 bits (140), Expect = 4e-09,   Method: Compositional matrix adjust.
 Identities = 47/177 (26%), Positives = 89/177 (50%), Gaps = 11/177 (6%)
 Frame = -2

Query: 72   MKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEY----VAGG 127
            ++ L+ + VV+L++I HT       QA  +          +  S  Y++ EY    +AG 
Sbjct: 1059 LQQLEHENVVQLQEICHT-------QAGPY---------NRYKSTFYLIFEYCDYDLAG- 931

Query: 128  EMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFG 187
             + ++LR   +FS    +   +Q++    Y+H+  +++RD+K  N+L+ + G +++ DFG
Sbjct: 930  -LLNNLRV--KFSLADKKNLMSQLLNGLFYIHTKQILHRDIKAANILLTRDGVLKLADFG 760

Query: 188  F------AKRVKGRTWTLCGTPEYLAPEIILS-KGYNKAVDWWALGVLIYEMAAGYP 237
                   +KR+  R  TL     Y  PE++L  + Y   +D W +G ++ EM +  P
Sbjct: 759  LSRPWVKSKRLTNRVVTLW----YRPPELLLGEREYGPEIDMWGVGCIMAEMWSRKP 601
>04852
          Length = 1462

 Score = 58.2 bits (139), Expect = 5e-09,   Method: Compositional matrix adjust.
 Identities = 35/121 (28%), Positives = 61/121 (50%), Gaps = 8/121 (6%)
 Frame = +1

Query: 147 YAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFA-------KRVKGRTWTL 199
           YA QI    E+L S   I+RDL   N+L+ ++  +++ DFG +       KR  GR    
Sbjct: 340 YAFQIARGMEFLASRKCIHRDLAARNVLVTEEHVLKIADFGLSRTGDYYKKRSGGRL--- 510

Query: 200 CGTPEYLAPEIILSKGYNKAVDWWALGVLIYEM-AAGYPPFFADQPIQIYEKIVSGKVRF 258
               +++APE +    Y    D W+ GV+++E+ + G  P+ +    ++Y K++    R 
Sbjct: 511 --PVKWMAPEALFDMRYTTKSDVWSFGVVLWEIFSLGGMPYASIPNEELYSKLLDDAYRM 684

Query: 259 P 259
           P
Sbjct: 685 P 687
>32957
          Length = 645

 Score = 56.6 bits (135), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 24/41 (58%), Positives = 30/41 (73%)
 Frame = +3

Query: 194 GRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAA 234
           GRT T CGT EY+APE+   K Y K VDWW LG+L++E+ A
Sbjct: 30  GRTRTFCGTREYMAPEVHERKEYGKEVDWWGLGILLHELLA 152
>12786
          Length = 460

 Score = 54.7 bits (130), Expect = 5e-08,   Method: Compositional matrix adjust.
 Identities = 34/120 (28%), Positives = 58/120 (48%), Gaps = 25/120 (20%)
 Frame = -3

Query: 145 RFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRV-KGRTWTL---- 199
           +FY  +++   + LH+  +I+ DLKP N ++   G +++ DFG A  + + +T  L    
Sbjct: 401 KFYWREMLRAVKALHNEGVIHSDLKPANFML-VAGNLKLIDFGIANTLQQDKTSVLKDSR 225

Query: 200 CGTPEYLAPEIILSKGYNKA--------------------VDWWALGVLIYEMAAGYPPF 239
            GTP Y++PE I++   + A                     D W+LG ++Y M  G  PF
Sbjct: 224 VGTPSYMSPEAIMAACDDSADDSMEEDGHRTKPKYKVGVRSDVWSLGCILYNMVYGRTPF 45
>07940
          Length = 1336

 Score = 54.7 bits (130), Expect = 6e-08,   Method: Compositional matrix adjust.
 Identities = 29/91 (31%), Positives = 50/91 (54%), Gaps = 5/91 (5%)
 Frame = -3

Query: 147 YAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKG----RTWTLCGT 202
           YA Q+    EYL S   I+RDL   N+L+ ++  +++ DFG  + ++     R  T    
Sbjct: 332 YAYQVARGMEYLASKQCIHRDLAARNVLVAEEYVLKIADFGLTRNLQQFDYYRKTTDGRL 153

Query: 203 P-EYLAPEIILSKGYNKAVDWWALGVLIYEM 232
           P +++APE +  + Y    D W+ GVL++E+
Sbjct: 152 PVKWMAPEALFDRKYTSKSDVWSYGVLLWEI 60
>11780
          Length = 1713

 Score = 54.3 bits (129), Expect = 8e-08,   Method: Compositional matrix adjust.
 Identities = 39/145 (26%), Positives = 66/145 (45%), Gaps = 2/145 (1%)
 Frame = +3

Query: 48  KTLGTGSFGRVMLVKHKESGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKL 107
           + +G G FG V        G +    +  KQ   K +  +  L E  ++ ++    LV+L
Sbjct: 615 EAIGKGDFGDVY------KGMYRGQPVAIKQLKDKDRGEQSFLQEASVMTSLRHDNLVRL 776

Query: 108 EFSFKDNSNLYMVMEYVAGGEMFSHLRRIGR--FSEPHARFYAAQIVLTFEYLHSLDLIY 165
                    +++V E++  G +  +LR  GR   ++     +A       EYL S  L++
Sbjct: 777 -IGVVLGETIFLVTEFMGKGNLVEYLRSRGRSVITKKDQINFATDTCAAMEYLESKRLVH 953

Query: 166 RDLKPENLLIDQQGYIQVTDFGFAK 190
           RDL   N+L+   G  +V+DFG AK
Sbjct: 954 RDLAARNVLVHDDGKAKVSDFGLAK 1028
>04138
          Length = 800

 Score = 53.9 bits (128), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 29/88 (32%), Positives = 47/88 (53%), Gaps = 7/88 (7%)
 Frame = +1

Query: 157 YLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAK------RVKGRTWTLCGTPEYLAPEI 210
           Y+H   +++RD+K  N+LI +QG +++ DFG A+      R   R      T  Y  PE+
Sbjct: 58  YIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRVVTLWYRPPEL 237

Query: 211 ILS-KGYNKAVDWWALGVLIYEMAAGYP 237
           +L  + Y+ A+D W  G ++ EM    P
Sbjct: 238 LLGDRNYSTAIDQWGAGCIMAEMWTRNP 321
>00715
          Length = 1788

 Score = 52.4 bits (124), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 53/226 (23%), Positives = 97/226 (42%), Gaps = 29/226 (12%)
 Frame = +1

Query: 61  VKHKESGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMV 120
           + HK S N  A++     +++  +     +N   IL A +          F+D +  ++ 
Sbjct: 19  IYHKRSSNPRALRQSYSNELLAFRCGLRHVNVVSILGATSL-------HRFEDGA--WLA 171

Query: 121 MEYVAGGEMFSHLRRIGRFSEPHARF-YAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQG 179
           MEYV    + + L    +  +   R   A Q+     YLHS+++++ DLKP N L+ +  
Sbjct: 172 MEYVGPLNLQTILNDHQQDIDSSMRLSLALQMARGLHYLHSINIVHLDLKPANCLLTRDL 351

Query: 180 YIQVTDFGFAKR------------------------VKGRTWT--LCGTPEYLAPEIILS 213
            +++ DFG   +                        V+G  W   L GT  Y APE++  
Sbjct: 352 KLRIADFGCCHQLTPTGLDMGEREGGMAGNELELTPVQG-AWKNELAGTLAYRAPELL-- 522

Query: 214 KGYNKAV--DWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVR 257
           KG   +V  D ++LG+ +++M     P+       +  ++VS  +R
Sbjct: 523 KGLQPSVRSDVYSLGITLWQMCTRQGPYEGVPAHAVVYQVVSKDLR 660
>03508
          Length = 1463

 Score = 52.0 bits (123), Expect = 4e-07,   Method: Compositional matrix adjust.
 Identities = 30/113 (26%), Positives = 62/113 (54%), Gaps = 4/113 (3%)
 Frame = +1

Query: 139 FSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQG-YIQVTDFGFAKRVK-GRT 196
           F++   RFY  +++   ++ HS+ +++RD+KP N++ID +   +++ D+G A+    G  
Sbjct: 862 FTDYDIRFYLYELMKALDFCHSMGIMHRDVKPHNVMIDHENKKLRLIDWGLAEFYHPGME 1041

Query: 197 WTLCGTPEYL-APEIILS-KGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQI 247
           + +     Y   PE++L  + Y+ ++D W+LG +   M     P    +P Q+
Sbjct: 1042YNVRVASRYFKGPELLLDYQMYDYSLDMWSLGCMFASMIFRKEPLLP-RPRQL 1197
>37602
          Length = 804

 Score = 50.8 bits (120), Expect = 7e-07,   Method: Compositional matrix adjust.
 Identities = 26/90 (28%), Positives = 43/90 (47%)
 Frame = -1

Query: 97  QAVNFPFLVKLEFSFKDNSNLYMVMEYVAGGEMFSHLRRIGRFSEPHARFYAAQIVLTFE 156
           + VN    V    S+     L++ MEY  GG M       G  +EP   F   + +    
Sbjct: 354 RIVNIQTFVGYFDSYLRREKLWIAMEYCGGGSMQDIYHVTGPLTEPQIAFVCRETLKGLH 175

Query: 157 YLHSLDLIYRDLKPENLLIDQQGYIQVTDF 186
           YLH    ++RD+K  N+L+ ++G +++ DF
Sbjct: 174 YLHRRGKMHRDIKGANILLTEEGDVKLADF 85
>20152
          Length = 445

 Score = 50.8 bits (120), Expect = 8e-07,   Method: Compositional matrix adjust.
 Identities = 29/96 (30%), Positives = 44/96 (45%), Gaps = 1/96 (1%)
 Frame = +1

Query: 208 PEIILSKGYN-KAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDL 266
           PEI+L   Y+  AVD W+LGV++Y +  G  PF      +    I+  + + P H S   
Sbjct: 1   PEILLGDSYDAPAVDVWSLGVILYMLVVGEAPFQEANDSETLTMIMDCRYQIPPHISHKC 180

Query: 267 KDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTD 302
           +DL+  +LQ +   R       +  I  H W    D
Sbjct: 181 QDLIEKMLQREPVDR-----ASLPHILAHPWLNDGD 273
>16708
          Length = 1397

 Score = 48.9 bits (115), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 40/161 (24%), Positives = 69/161 (42%), Gaps = 14/161 (8%)
 Frame = -1

Query: 47   IKTLGTGSFGRVMLVKHKESGNHYAMKILDKQKVVKLKQ---IEHTLNEKRILQAVNFPF 103
            ++ LG G FG+V           Y  ++L   +   LK      H+L+E   L  +   F
Sbjct: 1388 LQVLGKGVFGKV-----------YEARLLSTHEKAALKTSILCHHSLDEVEALGRIEGGF 1242

Query: 104  LVKLEFS-------FKDNSNLYMVMEYVAGGEMFSHLRRIG---RFSEPH-ARFYAAQIV 152
             +   F        F   + L    E      +++H +      R+S P      A Q V
Sbjct: 1241 YLAQMFGAWVTCLPFPKMNILLHFYEMGPLCNVYAHYKNKEMPIRWSNPAMVCCIAGQXV 1062

Query: 153  LTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVK 193
               E++H L +++ D+K +N+L+D  G  ++TD+G A+  K
Sbjct: 1061 CALEHIHELGVVHMDVKADNVLVDAHGNCKLTDYGIAQLYK 939
>14116
          Length = 1017

 Score = 47.8 bits (112), Expect = 8e-06,   Method: Compositional matrix adjust.
 Identities = 27/123 (21%), Positives = 61/123 (49%), Gaps = 9/123 (7%)
 Frame = -1

Query: 119 MVMEYVAGGEMFSHLRRIGRFSEPHAR---FYAAQIVLTFEYLHSLDLIYRDLKPENLLI 175
           +V+ ++  G++ +++R      +P  +    Y   I    +YL  L  ++RDL   N ++
Sbjct: 393 VVLPFMKHGDLLTYIR--DDQHQPTIKDLIMYGVDIARGMDYLAGLKFVHRDLAARNCML 220

Query: 176 DQQGYIQVTDFGFAKRVKGRTWTLCGTP------EYLAPEIILSKGYNKAVDWWALGVLI 229
           D+  +++V DFG A+ +  + +            +++A E +    Y+   D W+ GV++
Sbjct: 219 DEDFHVKVADFGLARDIYEKEYYSSENKKAKLPVKWMALESLEKGNYDSKTDVWSYGVVL 40

Query: 230 YEM 232
           +E+
Sbjct: 39  WEL 31
>27274
          Length = 396

 Score = 46.6 bits (109), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 28/102 (27%), Positives = 49/102 (48%), Gaps = 11/102 (10%)
 Frame = -1

Query: 209 EIILSKGYNKAVDWWALGVLIYEMAAGYPPF--------FADQPIQIYEKIVSGKVRFPS 260
           E++  + +   VD W+LG+L++E+ +G+ PF         A   + +Y +I+ G  R   
Sbjct: 375 ELLRGQQHGPTVDMWSLGILLHELLSGHVPFEPERGSRQMARNMMAVYAQIIRGSSRDVC 196

Query: 261 H---FSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFA 299
                S+   D LR L+Q++ TKR  +         +H W A
Sbjct: 195 DGLALSTHGADFLRRLVQLEDTKRLTS-----QQAFSHPWIA 85
>17300
          Length = 480

 Score = 45.8 bits (107), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 41/152 (26%), Positives = 71/152 (46%), Gaps = 14/152 (9%)
 Frame = +1

Query: 158 LHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRT----WTLCGTP---EYLAPEI 210
           L  +  ++RDL   N+L+++    +V DFG ++ ++  T    +T  G      + APE 
Sbjct: 22  LADMGYVHRDLAARNILVNEILVCKVADFGLSREIESDTTEGAYTTKGGKIPVRWTAPEA 201

Query: 211 ILSKGYNKAVDWWALGVLIYE-MAAGYPPFFADQPIQIYEKIVSGKVRFPSH------FS 263
           I  + +  A D W+ GV+++E M+ G  P++ +   Q   K V    R P H       S
Sbjct: 202 IAYRKFTSASDVWSFGVVMWEVMSYGERPYW-NWSNQDVIKAVEKGYRLPLHGLSGSPSS 378

Query: 264 SDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNH 295
           +D + L     ++  TK   N+  G N  + H
Sbjct: 379 TDARRLAEG--EISQTK---NVHGG*NTRQTH 459
>07291
          Length = 833

 Score = 45.8 bits (107), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 25/100 (25%), Positives = 54/100 (54%), Gaps = 7/100 (7%)
 Frame = +1

Query: 147 YAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTW-TLCGTP-- 203
           +  QI     YL  + +++R+L   N ++ + G +Q++D+G    +  +++ T   +P  
Sbjct: 64  FGRQIADGMAYLQEVKVVHRNLAARNCIVTEDGRLQLSDYGVTGSLFPQSYYTADDSPAR 243

Query: 204 ---EYLAPEIILSKGYNKAVDWWALGVLIYEMAA-GYPPF 239
              +++APE I +  ++   D WA GV+++E+   G  P+
Sbjct: 244 DLVKWMAPETIDNFHFSSKSDVWAFGVVLWELLTRGITPY 363
>17932
          Length = 597

 Score = 45.1 bits (105), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 32/110 (29%), Positives = 51/110 (46%), Gaps = 3/110 (2%)
 Frame = -3

Query: 243 QPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTD 302
           QPI I   I   +V   S  S + +DL+  LL        G  + G  +++ H +F T D
Sbjct: 517 QPITIS*TIRQTQVPPHSSVSKEARDLISQLLSD------GKSRLGWPELQQHPFFKTVD 356

Query: 303 WIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSIN---EKCGKEFT 349
           W  I  R    P++P      DTS+FD+ E+     +I+   +   ++FT
Sbjct: 355 WANI--RNAMPPYVPSISSLDDTSHFDEVEKARPAPNIDSFHQPSSRDFT 212

 Score = 32.3 bits (72), Expect = 0.30,   Method: Compositional matrix adjust.
 Identities = 16/41 (39%), Positives = 20/41 (48%), Gaps = 2/41 (4%)
 Frame = -2

Query: 222 WWALGVLIYEMAAGYPPFFADQP--IQIYEKIVSGKVRFPS 260
           WW+LGV  YEM  G  PF  D    +  Y  I++ K    S
Sbjct: 596 WWSLGVCAYEMLFGCTPFTDDDGSMVATYNNIMNYKTNSSS 474
>02638
          Length = 1490

 Score = 44.7 bits (104), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 27/105 (25%), Positives = 49/105 (46%), Gaps = 5/105 (4%)
 Frame = +1

Query: 199 LCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFA---DQPIQIYEKIVSG- 254
           L GT  ++APE++  + Y +A D W++G ++ EM    PP+ +      + +  KI S  
Sbjct: 16  LLGTIAFMAPEVLRGESYGRACDVWSVGCVMIEMCTCRPPWNSHDISNHLALIFKIASSV 195

Query: 255 -KVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWF 298
                P + S  ++DL+   L+ D      + +    D+  H  F
Sbjct: 196 DPPPIPENMSPPVRDLMLRCLEQD-----SDFRPSAKDLLMHPLF 315
>33586
          Length = 551

 Score = 43.1 bits (100), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 16/49 (32%), Positives = 33/49 (67%)
 Frame = +2

Query: 103 FLVKLEFSFKDNSNLYMVMEYVAGGEMFSHLRRIGRFSEPHARFYAAQI 151
           F+V L ++F+    LY+++E++ GG++F+ L +   F+E   +FY A++
Sbjct: 404 FIVHLHYAFQTEGKLYLILEFLRGGDLFTRLSKEVMFTEEDVKFYLAEL 550

 Score = 27.3 bits (59), Expect = 8.7,   Method: Compositional matrix adjust.
 Identities = 11/16 (68%), Positives = 13/16 (81%)
 Frame = +1

Query: 43  QFDRIKTLGTGSFGRV 58
           QF+ +K LG GSFGRV
Sbjct: 217 QFELLKVLGQGSFGRV 264
>18401
          Length = 463

 Score = 42.7 bits (99), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 16/42 (38%), Positives = 26/42 (61%)
 Frame = -3

Query: 198 TLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPF 239
           T+  T  Y APE+IL  G++   D W++G +++E+  GY  F
Sbjct: 455 TIVSTRHYRAPEVILELGWSHPCDVWSVGCIMFELYTGYTLF 330
>14477
          Length = 493

 Score = 42.0 bits (97), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 35/152 (23%), Positives = 71/152 (46%), Gaps = 2/152 (1%)
 Frame = -1

Query: 43  QFDRIKTLGTGSFGRVM--LVKHKESGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVN 100
           Q D +K LG G+FG VM  + +  +     A+K+L    +    Q E  + E  +++ ++
Sbjct: 484 QMDELK-LGAGNFGSVMKGVCRLDDREIPVAIKVLKNADLDPSVQSE-LIKEAEVMKKMD 311

Query: 101 FPFLVKLEFSFKDNSNLYMVMEYVAGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHS 160
              +V+L     +   + +V+E    G +   L +       +      Q+    EYL +
Sbjct: 310 HMHIVRL-IGLCEGETMMLVLELAKLGPLNKFLPKNKHLPLWNILELMWQVSQGMEYLEA 134

Query: 161 LDLIYRDLKPENLLIDQQGYIQVTDFGFAKRV 192
              ++RDL   N+L+  + + +++DFG +K +
Sbjct: 133 NKFVHRDLAARNILLCDEHFAKISDFGMSKTL 38
>12672
          Length = 773

 Score = 41.2 bits (95), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 28/88 (31%), Positives = 46/88 (52%), Gaps = 7/88 (7%)
 Frame = +3

Query: 155 FEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGF---AKRVKGRTW----TLCGTPEYLA 207
            +YL+    ++RD+K  N+L+D +   +V DF     A   +G+T      + GT  YLA
Sbjct: 30  IQYLNDNGHVHRDIKTANILLDSEYTAKVGDFATVVSAPSGEGKTVQNASVVIGTAAYLA 209

Query: 208 PEIILSKGYNKAVDWWALGVLIYEMAAG 235
           PE I      K +D ++ GV++ E+  G
Sbjct: 210 PEAIHFDVSTK-LDSYSFGVVLLEVITG 290
>31489
          Length = 329

 Score = 40.8 bits (94), Expect = 9e-04,   Method: Compositional matrix adjust.
 Identities = 24/69 (34%), Positives = 40/69 (57%), Gaps = 4/69 (5%)
 Frame = +3

Query: 110 SFKDNSNLYMVMEYVAGGEMFSHLRRIGRFSEP----HARFYAAQIVLTFEYLHSLDLIY 165
           S+ D  ++++V +      M S L RI    +P    H R++  QI+   +Y+HS ++++
Sbjct: 72  SYHDFKDIHVVFDL-----MESDLHRIIYSDQPLTEEHIRYFLYQILRGLKYIHSANVVH 236

Query: 166 RDLKPENLL 174
           RDLKP NLL
Sbjct: 237 RDLKPSNLL 263
>29590
          Length = 320

 Score = 40.4 bits (93), Expect = 0.001,   Method: Composition-based stats.
 Identities = 17/41 (41%), Positives = 25/41 (60%)
 Frame = +3

Query: 199 LCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPF 239
           + GTP+Y+APE++  +  +   D W+LGVL Y M     PF
Sbjct: 54  IIGTPDYVAPEVLDYEPLSIQTDMWSLGVLSYVMLTACSPF 176
>26009
          Length = 886

 Score = 40.0 bits (92), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 23/72 (31%), Positives = 35/72 (48%), Gaps = 3/72 (4%)
 Frame = +3

Query: 127 GEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQV--- 183
           G   +  RR        A+    Q+V   +++HS  L++RD+KPEN+LI    + +V   
Sbjct: 666 GTCLTPSRRNKACGSREAKSVMKQLVSALDFMHSKQLVHRDIKPENVLILTPDFSRVS*W 845

Query: 184 TDFGFAKRVKGR 195
           T    A RV  R
Sbjct: 846 TSA*LANRVHRR 881
>11404
          Length = 563

 Score = 38.9 bits (89), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 39/140 (27%), Positives = 69/140 (49%), Gaps = 6/140 (4%)
 Frame = +1

Query: 42  DQFDRIKTLGTGSFGRVMLVKHKESGNHYAMKIL-DKQKVVKLKQIEHTLNEKRILQAV- 99
           D+++    +G GSFG+V+           A+KI+ +K+  +   QIE  L E        
Sbjct: 139 DRYEIDSLIGKGSFGQVVKAYDHTDNEQVAIKIIKNKKPFLNQAQIEVKLLEMMNRHDTD 318

Query: 100 NFPFLVKLEFSFKDNSNLYMVMEYVAGGEMFSHLRRIG--RFSEPHARFYAAQIVLTFEY 157
           N  ++V+L+  F   S+L +V E ++   ++  LR       S    R +A Q+     +
Sbjct: 319 NKYYIVRLKRHFMFRSHLCLVFELLSYN-LYDLLRNTNFRGVSLNLTRKFAQQLCTALLF 495

Query: 158 LHS--LDLIYRDLKPENLLI 175
           L +  + +I+ DLKPEN+L+
Sbjct: 496 LATPEMSIIHCDLKPENILL 555
>21800
          Length = 855

 Score = 38.5 bits (88), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 36/148 (24%), Positives = 61/148 (41%), Gaps = 3/148 (2%)
 Frame = +2

Query: 31  WETPSQNTAQLDQFDRIKTLGTGSFGRVMLVKHKESGNHYAMKILDKQKVVKLKQIEHTL 90
           W  P +  A L        L       V   +  ES  HY    LD+ K++K  +     
Sbjct: 305 WTVPCRQKAGLGSLLHCLALLGSQL*AVCRFEGCESAQHYTETALDEIKLLKCVRNSDET 484

Query: 91  NEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVAGGEMFSHLRRIGRFSEP--HARFYA 148
           +  R     +   L   + S  + +++ MV E V G  +   + R      P  + +   
Sbjct: 485 DPAR---EKSVQLLDDFKISGVNGTHVCMVFE-VLGYNLLKLIIRSNYQGIPVHNVKLII 652

Query: 149 AQIVLTFEYLHS-LDLIYRDLKPENLLI 175
            Q++    YLH+  ++I+ D+KPEN+LI
Sbjct: 653 RQVLEGLNYLHAKCNIIHTDIKPENILI 736
>37063
          Length = 455

 Score = 38.5 bits (88), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 24/78 (30%), Positives = 40/78 (51%), Gaps = 16/78 (20%)
 Frame = -2

Query: 168 LKPENLL---IDQQGYIQVTDFGFAKRVKG--------RTWTLCGTPEYLAPEII----- 211
           LKPEN+L   +D+   +++ DF  A  +             T  G+ EY+APE++     
Sbjct: 454 LKPENILCEHLDEVVPLKICDFDLASGINCDGDGTKTPELLTPVGSAEYMAPEVVDAWVG 275

Query: 212 LSKGYNKAVDWWALGVLI 229
            S  Y+K  D W+LG+++
Sbjct: 274 ESFSYDKRCDMWSLGIIL 221
>18481
          Length = 437

 Score = 38.1 bits (87), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 26/86 (30%), Positives = 43/86 (50%), Gaps = 5/86 (5%)
 Frame = -1

Query: 119 MVMEYVAGG--EMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLID 176
           +VME +     E+F   +R  RF+       + Q++   E++H    I+RDLKP+N L+ 
Sbjct: 266 LVMELLGPSLEELFVICKR--RFTLKTILMVSDQLLSRLEFIHQKCFIHRDLKPDNFLMG 93

Query: 177 QQGYIQ---VTDFGFAKRVKGRTWTL 199
              +     + DFG +KR K    T+
Sbjct: 92  LGRHCHRLYIIDFGLSKRYKDTQGTM 15
>17516
          Length = 453

 Score = 38.1 bits (87), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 17/39 (43%), Positives = 28/39 (71%), Gaps = 1/39 (2%)
 Frame = -3

Query: 198 TLCGTPEYLAPEIILSKG-YNKAVDWWALGVLIYEMAAG 235
           TL GTP Y+APE++L KG Y+   D ++L ++++E+  G
Sbjct: 442 TLAGTPVYMAPEVLLQKGQYDMKADVYSLAIILWELWYG 326
>20640
          Length = 1492

 Score = 38.1 bits (87), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 25/86 (29%), Positives = 42/86 (48%), Gaps = 5/86 (5%)
 Frame = +1

Query: 164 IYRDLKPENLLIDQQGYIQVTDFGFAKRVKG----RTWTLCGTP-EYLAPEIILSKGYNK 218
           ++RDL   N L+     ++++DFG A+ V      R       P  ++  E IL   ++ 
Sbjct: 10  VHRDLATRNCLVGHDLVVKISDFGLARSVHSVDYYRGSEHDAIPIRWMPLEAILYNKFST 189

Query: 219 AVDWWALGVLIYEMAAGYPPFFADQP 244
             D W+ GV+++E+ A     FA QP
Sbjct: 190 QSDVWSFGVVLWEIFA-----FALQP 252
>17253
          Length = 483

 Score = 37.7 bits (86), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 20/86 (23%), Positives = 44/86 (51%), Gaps = 12/86 (13%)
 Frame = -1

Query: 119 MVMEYVAGGEMFSHLRR---------IGRFSEPHAR---FYAAQIVLTFEYLHSLDLIYR 166
           ++ME+   G++ S LR+             ++  AR    +A  +     ++ +  +++R
Sbjct: 315 ILMEFCCHGDLLSFLRKRRPDRTVFLTSTANDLTARDFFSFALHVARGMAHVANNKIVHR 136

Query: 167 DLKPENLLIDQQGYIQVTDFGFAKRV 192
           D+   N+LI ++   +V+DFG ++RV
Sbjct: 135 DVAARNVLISERNVCKVSDFGLSRRV 58
>18996
          Length = 491

 Score = 37.0 bits (84), Expect = 0.011,   Method: Compositional matrix adjust.
 Identities = 21/74 (28%), Positives = 41/74 (55%), Gaps = 5/74 (6%)
 Frame = +2

Query: 164 IYRDLKPENLLIDQQGYIQVTDFGFAK--RVKGRTWTLCGTP---EYLAPEIILSKGYNK 218
           I+RDL   N+L+D+   ++++DFG A+     G  + +       ++ +PE I +  ++ 
Sbjct: 2   IHRDLAARNILVDR-SCVKISDFGLAQFANADGYYYGISQRDIPIKWYSPEAIETCKFSS 178

Query: 219 AVDWWALGVLIYEM 232
             D W+ GV ++EM
Sbjct: 179 YSDVWSYGVTLFEM 220
>01106
          Length = 878

 Score = 37.0 bits (84), Expect = 0.012,   Method: Compositional matrix adjust.
 Identities = 41/166 (24%), Positives = 71/166 (42%), Gaps = 15/166 (9%)
 Frame = +3

Query: 25  EDFLKKWETPSQNTAQLD-QFDRIKTLGTGSFGRVML-----------VKHKESGNHYAM 72
            D+ K    P +N    + ++  I+ LG G F  V L           +K  +S  HY  
Sbjct: 264 RDYCKGGYHPVKNGDLFNGRYHVIRKLGWGHFSTVWLCWDLTCKRFVALKVVKSAQHYTE 443

Query: 73  KILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVAGGEMFSH 132
             LD+ K++K  +     +  R   A     L   + S  + +++ MV E V G  +   
Sbjct: 444 TALDEVKLLKCVRESDVADPAR---AKCVQLLDDFKISGVNGTHVAMVFE-VLGYNLLKL 611

Query: 133 LRRIGRFSEP--HARFYAAQIVLTFEYLHS-LDLIYRDLKPENLLI 175
           + R      P  + +    Q++    Y+H+   +I+ D+KPEN+LI
Sbjct: 612 IIRSNYQGIPIHNVKLIIRQVLEGLSYMHAKCRIIHTDIKPENILI 749
>17637
          Length = 447

 Score = 37.0 bits (84), Expect = 0.012,   Method: Compositional matrix adjust.
 Identities = 24/89 (26%), Positives = 42/89 (47%), Gaps = 6/89 (6%)
 Frame = +1

Query: 172 NLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEY-----LAPEIILSKGYNKAVDWWALG 226
           N +ID Q  +++TD   ++ +    +   G  EY     L+ E +    YN+  D W+ G
Sbjct: 1   NCVIDDQLRVKLTDSALSRDLFSGDYNCLGDGEYRPIKWLSLEALQKSHYNEGSDVWSFG 180

Query: 227 VLIYEMAA-GYPPFFADQPIQIYEKIVSG 254
           VL++EM   G  P+    P ++   +  G
Sbjct: 181 VLMWEMCTLGKLPYAEIDPYEMEHYLKDG 267
>36481
          Length = 806

 Score = 36.6 bits (83), Expect = 0.016,   Method: Compositional matrix adjust.
 Identities = 33/132 (25%), Positives = 60/132 (45%), Gaps = 4/132 (3%)
 Frame = +2

Query: 51  GTGSFGRVMLVKHKESGNHYAMKIL-DKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEF 109
           G G+FG+V+  K    G+  A+KI+ +  K  +  ++E  + EK   +  +   +     
Sbjct: 389 GEGTFGKVVQCKDLLKGDDIALKIIKNVDKYREAAKLEINVLEKLREKDPHAKHMCVQML 568

Query: 110 SFKDNSNLYMVMEYVAGGEMFSHLR--RIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRD 167
            + D      +  ++ G  +F  L+    G +     R  + Q+     +LH   L + D
Sbjct: 569 DWFDYHGHVCISFHMLGLSVFDFLKDNSYGAYPIEQVRHISYQLCYAVNFLHENQLTHTD 748

Query: 168 LKPENLL-IDQQ 178
           LKPEN+L +D Q
Sbjct: 749 LKPENILFVDSQ 784
>06358
          Length = 1517

 Score = 36.2 bits (82), Expect = 0.020,   Method: Compositional matrix adjust.
 Identities = 32/154 (20%), Positives = 68/154 (44%), Gaps = 22/154 (14%)
 Frame = +3

Query: 150 QIVLTFEYLHS-LDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTP----- 203
           Q+     +LH+   +++R++ PE +++ + G  ++  + F  R      T    P     
Sbjct: 384 QVTEALGFLHNDAKMMHRNVCPEAIMLTKLGSWKLAGYEFCVRSSDPQSTDPSYPFYEWR 563

Query: 204 -----------EYLAPEIILSKGYNKAVDWWALGVLIYEM-AAGYPPFFADQPIQIY--- 248
                      +++APE +L+       D ++LG+L+Y + A G P F  +  +  +   
Sbjct: 564 SDIAPVTQPHLDFMAPEYVLTMQCGTGSDMFSLGLLVYSVFAKGKPLFECNGELSAFKSN 743

Query: 249 -EKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKR 281
            E++   +V        DL+D ++ LL ++   R
Sbjct: 744 AEELRHMRVSLLGVVPEDLRDHVKLLLNIEPAVR 845
>25360
          Length = 751

 Score = 35.0 bits (79), Expect = 0.040,   Method: Compositional matrix adjust.
 Identities = 21/54 (38%), Positives = 28/54 (51%), Gaps = 5/54 (9%)
 Frame = -3

Query: 166 RDLKPENLLIDQQGYI-QVTDFGFAKRVKGRTWT--LCGTPEYL--APEIILSK 214
           R L P  L    QG   +V D G+A  V G+TWT  +CGTP +    P  + S+
Sbjct: 422 RSLTPGGLEALFQGQCPRVQDLGWASHVNGKTWTHYVCGTPHWQHDCPRRVRSR 261
>11089
          Length = 1213

 Score = 34.7 bits (78), Expect = 0.053,   Method: Compositional matrix adjust.
 Identities = 21/54 (38%), Positives = 28/54 (51%), Gaps = 5/54 (9%)
 Frame = +2

Query: 166  RDLKPENLLIDQQGYI-QVTDFGFAKRVKGRTWT--LCGTPEYL--APEIILSK 214
            R L P  L    QG   +V D G+A  V G+TWT  +CGTP +    P  + S+
Sbjct: 974  RSLTPGGLEALFQGQCPRVQDLGWASHVNGKTWTHYVCGTPHWQHDCPRRVRSR 1135
>21210
          Length = 518

 Score = 34.7 bits (78), Expect = 0.063,   Method: Compositional matrix adjust.
 Identities = 27/91 (29%), Positives = 43/91 (47%), Gaps = 10/91 (10%)
 Frame = +3

Query: 201 GTPEYLAPEII----LSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIY---EKIVS 253
           G   Y+APE I     S GY+   D W+LG+ + E+A G  P+   + + I+   +++V 
Sbjct: 6   GCRPYMAPERIDPRASSHGYDVRSDVWSLGITLMELATGRFPY--RKWVSIFDQLQQVVR 179

Query: 254 GKVRFPSH---FSSDLKDLLRNLLQVDLTKR 281
           G      H   FS D  + +   L  D  +R
Sbjct: 180 GVAPCLPHDGAFSHDFVNFVNKCLTKDEKQR 272
>26052
          Length = 562

 Score = 34.3 bits (77), Expect = 0.075,   Method: Compositional matrix adjust.
 Identities = 15/31 (48%), Positives = 22/31 (70%)
 Frame = -1

Query: 43  QFDRIKTLGTGSFGRVMLVKHKESGNHYAMK 73
           Q+   K LG GSFG+VM ++HK++G   A+K
Sbjct: 388 QYLFXKLLGVGSFGKVMALQHKDTGETLAVK 296
>17591
          Length = 474

 Score = 32.7 bits (73), Expect = 0.21,   Method: Compositional matrix adjust.
 Identities = 14/46 (30%), Positives = 28/46 (60%)
 Frame = +2

Query: 230 YEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQ 275
           +EM  G PPF++    ++YE I+   +R  ++ S+  +++L  LL+
Sbjct: 2   FEMLYGLPPFYSRDTSEMYENILYKPLRLRTNVSAAGRNILEELLK 139
>24241
          Length = 413

 Score = 32.0 bits (71), Expect = 0.39,   Method: Compositional matrix adjust.
 Identities = 21/94 (22%), Positives = 42/94 (44%), Gaps = 12/94 (12%)
 Frame = -2

Query: 44  FDRIKTLGTGSFGRVMLVKHKESGNHYAMKILDK------------QKVVKLKQIEHTLN 91
            DR+  +G G++G V   +H+ +G   AMK +              +++  L+++ HT  
Sbjct: 337 LDRLSKIGEGTYGVVYKCRHRATGRKLAMKKIRLRGSEDGVPSSAIREIAMLRELRHT-- 164

Query: 92  EKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVA 125
                       LV LE    ++  L++V E+++
Sbjct: 163 ----------QXLVCLEDVIMEDERLFLVFEFLS 92
>28865
          Length = 342

 Score = 31.6 bits (70), Expect = 0.46,   Method: Compositional matrix adjust.
 Identities = 18/60 (30%), Positives = 29/60 (48%), Gaps = 3/60 (5%)
 Frame = -3

Query: 21  AKAKEDFLKKWETPSQNTAQLDQFDRI---KTLGTGSFGRVMLVKHKESGNHYAMKILDK 77
           AK  E+     +TP+     + Q  +I     LG+G FG V    H+ +    A+K++DK
Sbjct: 274 AKDNENVTANEDTPADKQVDISQLYQIFPEDVLGSGQFGIVYGGCHRRTNREVAIKVIDK 95
>31120
          Length = 439

 Score = 31.6 bits (70), Expect = 0.56,   Method: Compositional matrix adjust.
 Identities = 24/95 (25%), Positives = 43/95 (45%), Gaps = 1/95 (1%)
 Frame = +1

Query: 209 EIILSKGYN-KAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLK 267
           E++    Y+ K  D W+LGV+++ M  G  PF      ++ E   S K  F       + 
Sbjct: 1   EVVCGVPYDPKMADAWSLGVILFIMLNGKMPFDDSNLNKLLEDQRSKKYSFRRKLQDLVS 180

Query: 268 DLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTD 302
              R+ + V L +    ++  +N++ N +W  T D
Sbjct: 181 PNARSTVSV-LLEPNSAMRWDLNEVLNCQWLQTID 282
>32357
          Length = 625

 Score = 30.8 bits (68), Expect = 0.78,   Method: Compositional matrix adjust.
 Identities = 20/63 (31%), Positives = 33/63 (52%), Gaps = 1/63 (1%)
 Frame = -2

Query: 42  DQFDRIKTLGTGSFGRVMLVKHKESGNHYAMKILDKQKVVKLKQIEHTLNEKRILQ-AVN 100
            ++  +K +G+GSFG + L  H  SG   A+K+  + K  K  Q+ +     R+LQ  V 
Sbjct: 438 GKYRLMKKIGSGSFGEIYLGVHNTSGEEVAVKL--ELKNAKHPQLYYESKLYRVLQGGVG 265

Query: 101 FPF 103
            P+
Sbjct: 264 IPY 256
>00638
          Length = 1595

 Score = 30.8 bits (68), Expect = 0.82,   Method: Compositional matrix adjust.
 Identities = 11/38 (28%), Positives = 25/38 (65%)
 Frame = +2

Query: 139 FSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLID 176
           F++   RFY  +++   ++ HS+ +++RD+KP   L++
Sbjct: 407 FTDYDIRFYLYELMKALDFCHSMGIMHRDVKPSPPLVN 520
>30339
          Length = 384

 Score = 30.4 bits (67), Expect = 0.99,   Method: Compositional matrix adjust.
 Identities = 15/30 (50%), Positives = 19/30 (63%)
 Frame = -2

Query: 35 SQNTAQLDQFDRIKTLGTGSFGRVMLVKHK 64
          S +   L  F+ IK LG GSFG+VML + K
Sbjct: 95 SSDRFHLHDFNFIKVLGKGSFGKVMLAERK 6
>16350
          Length = 1108

 Score = 30.0 bits (66), Expect = 1.4,   Method: Compositional matrix adjust.
 Identities = 10/34 (29%), Positives = 18/34 (52%)
 Frame = +2

Query: 202 TPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAG 235
           T +Y   E+++  GY    D W+   + +E+A G
Sbjct: 419 TRQYRCLEVLIGAGYGTPADIWSTACMAFELATG 520
>06167
          Length = 1470

 Score = 28.9 bits (63), Expect = 3.2,   Method: Compositional matrix adjust.
 Identities = 12/42 (28%), Positives = 22/42 (52%)
 Frame = -2

Query: 183 VTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWA 224
           + D  FA R       +CG+   + P ++L+   NK+V +W+
Sbjct: 128 IIDESFACRFCM*YCVVCGSKYLILPSVLLNLNINKSVSFWS 3
>36002
          Length = 253

 Score = 28.9 bits (63), Expect = 3.3,   Method: Composition-based stats.
 Identities = 18/55 (32%), Positives = 26/55 (47%), Gaps = 4/55 (7%)
 Frame = +1

Query: 247 IYEKIVSGKVRFPSH----FSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKW 297
           ++ +I  G   FPS      SS  KDL+R+LL  +  KR+        D+  H W
Sbjct: 58  LFNRIQDGNYFFPSMEWSAISSSAKDLIRHLLVREPRKRY-----SAADVLKHPW 207
>23319
          Length = 2235

 Score = 28.5 bits (62), Expect = 4.5,   Method: Compositional matrix adjust.
 Identities = 10/33 (30%), Positives = 19/33 (57%)
 Frame = +3

Query: 208 PEIILSKGYNKAVDWWALGVLIYEMAAGYPPFF 240
           P++  +K Y+ ++D W+ G +  E+A    P F
Sbjct: 3   PDVYXAKMYSTSIDMWSAGCIFAELANAGRPLF 101
>17806
          Length = 433

 Score = 28.1 bits (61), Expect = 5.4,   Method: Compositional matrix adjust.
 Identities = 24/99 (24%), Positives = 47/99 (47%), Gaps = 7/99 (7%)
 Frame = +1

Query: 43  QFDRIKTLGTGSFGRVMLVKHKESGNHYAMKILDKQKVVKLKQIEHTLNEKRI------- 95
           Q   +K LGTG FG+V+    +         +   + VVK+ + + T +E+ +       
Sbjct: 52  QIVYLKELGTGWFGKVI----ESDAERITTGVSRSKVVVKMLKDDATKDEQLLFFEEVAP 219

Query: 96  LQAVNFPFLVKLEFSFKDNSNLYMVMEYVAGGEMFSHLR 134
            + ++ P +V+L     + + + M+ME  A G +  +LR
Sbjct: 220 FRELDHPNIVRLLGQCTEMNPMLMLMECAALGNLKQYLR 336
>29360
          Length = 363

 Score = 27.7 bits (60), Expect = 8.1,   Method: Compositional matrix adjust.
 Identities = 12/33 (36%), Positives = 19/33 (57%)
 Frame = +3

Query: 143 HARFYAAQIVLTFEYLHSLDLIYRDLKPENLLI 175
           + R    Q++     L  L LI+ DLKPEN+++
Sbjct: 261 YIRPITQQVLTALRKLKQLGLIHADLKPENIML 359
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|19526912|ref|NP_598487.1| suppression of
tumorigenicity 13 [Mus musculus]
         (371 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

04645                                                                 213   7e-56
08670                                                                  52   6e-07
30337                                                                  51   7e-07
01124                                                                  50   2e-06
35348                                                                  39   0.005
37348                                                                  38   0.008
03857                                                                  30   1.1  
06534                                                                  30   1.3  
23484                                                                  30   1.5  
20921                                                                  29   2.8  
13998                                                                  29   3.7  
18476                                                                  27   9.8  
>04645
          Length = 1075

 Score =  213 bits (543), Expect = 7e-56,   Method: Compositional matrix adjust.
 Identities = 103/226 (45%), Positives = 146/226 (64%), Gaps = 1/226 (0%)
 Frame = +3

Query: 9   LRAFVKMCRQDPSVLHTEEMRFLREWVESMGGKVPPATH-KAKSXXXXXXXXXXXXXXXN 67
           L+ FV++C+ + ++LHT E+ F +E++ES+GG +PP +  K +                 
Sbjct: 129 LKNFVQLCKANHNILHTPELAFYKEYIESLGGTIPPPSQPKKEPEEAPKAEASAPTPPPP 308

Query: 68  IKTXXXXXXXXXXXIDNEGVIEPDTDAPQEMGDENAEITEEMMDEANEKKGAAIEALNDG 127
            +            +DN GVI  D +   E  D N E+T++M+D+A++ +  A++A+ +G
Sbjct: 309 EEEEEDELVESDVELDNTGVITDDDEDMPEYADVNIEVTDDMIDQASDNRNQAMDAMAEG 488

Query: 128 ELQKAIDLFTDAIKLNPRLAILYAKRASVFVKLQKPNAAIRDCDRAIEINPDSAQPYKWR 187
            L+ AI  FTDAIK NP  A+LYAKR S ++K+ KP  AI DC +AIE+NPDSAQ YKWR
Sbjct: 489 RLEDAIGFFTDAIKSNPTSALLYAKRGSAYLKMGKPKKAIHDCSKAIELNPDSAQGYKWR 668

Query: 188 GKAHRLLGHWEEAAHDLALACKLDYDEDASAMLREVQPRAQKIAEH 233
           GKAH+LLGHWEE+ HDL LACKLDYD+DA+  L +V   A+KI EH
Sbjct: 669 GKAHKLLGHWEESYHDLTLACKLDYDDDANTALHDVTANAKKIMEH 806

 Score = 37.4 bits (85), Expect = 0.009,   Method: Compositional matrix adjust.
 Identities = 16/25 (64%), Positives = 20/25 (80%)
 Frame = +1

Query: 315  LNEILSDPEVLAAMQDPEVMVAFQD 339
            +  +L DPE+LAA+QDPEV  AFQD
Sbjct: 1000 MTTLLQDPELLAALQDPEVSAAFQD 1074
>08670
          Length = 1307

 Score = 51.6 bits (122), Expect = 6e-07,   Method: Compositional matrix adjust.
 Identities = 32/100 (32%), Positives = 55/100 (55%), Gaps = 1/100 (1%)
 Frame = +3

Query: 128 ELQKAIDLFTDAIKLNPRLAILYAKRASVFVKLQKPNAAIRDCDRAIEINPDSAQPYKWR 187
           E   AI LFT+AI L+P+       R+  + +LQ+   A++D ++AI+++ D  + Y  +
Sbjct: 417 EYSAAIQLFTEAIALDPKDFRFLGNRSYCYDRLQQYEKALKDAEKAIKLSKDWPKGYFRK 596

Query: 188 GKAHRLLGHWEEAAHDLALACKLDYD-EDASAMLREVQPR 226
           G+A   L  + EA        KLD + E+A   L++V+ R
Sbjct: 597 GRALAGLCKFSEAEESFLQVLKLDKNCEEAVQELQQVRTR 716
>30337
          Length = 493

 Score = 51.2 bits (121), Expect = 7e-07,   Method: Compositional matrix adjust.
 Identities = 35/114 (30%), Positives = 61/114 (53%), Gaps = 13/114 (11%)
 Frame = -1

Query: 115 EKKGAAIEALNDG-------ELQKAIDLFTDAIKLNPRLAILYAKRASVFVKLQKPNAAI 167
           ++K +AI+  N G       + + AI  +T AI  NP  A  +  RA  ++KL+    A 
Sbjct: 346 QRKMSAIDLKNQGNKLFAARKYEDAIHCYTKAIMKNPNTATYFTNRALCYIKLRNWELAS 167

Query: 168 RDCDRAIEINPDSAQPYKWRGKAHRLLGHWEEA------AHDLALACKLDYDED 215
           +DC RA+E++ +  + + + G+A   L  ++EA      AHDLA   KL++ ++
Sbjct: 166 QDCQRALELDRNLVKGHFFLGQALVELAMYDEAITHLMKAHDLAKDQKLNFGDE 5
>01124
          Length = 1372

 Score = 49.7 bits (117), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 35/111 (31%), Positives = 56/111 (50%), Gaps = 13/111 (11%)
 Frame = -3

Query: 127 GELQKAIDLFTDAIKLNPRLAILYAKRASVFVKLQKPNAAIRDCDRAIEI----NPDSA- 181
           G  Q A++++T A++LNP++  LY+ RA+  +KL+     I DC +A+++     P +A 
Sbjct: 713 GNYQAAVNVYTHALRLNPKMPSLYSNRAACHLKLRNLFKCIEDCSKAMDLLSPPVPQNAA 534

Query: 182 ---QPYKWRGKAHRLLGHWEEAAHDLALACKLD-----YDEDASAMLREVQ 224
              +    RG A   L  + E   D   A KLD       EDA  M + +Q
Sbjct: 533 SRVKAMVRRGTAFCQLEMYVEGLQDYEAALKLDPNNQQLKEDAEKMRQIIQ 381
>35348
          Length = 627

 Score = 38.5 bits (88), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 19/87 (21%), Positives = 46/87 (52%), Gaps = 5/87 (5%)
 Frame = -2

Query: 122 EALNDGELQKAIDLFTDAIKLNP-----RLAILYAKRASVFVKLQKPNAAIRDCDRAIEI 176
           +    G+  +A++L+++ + + P     + +++ + RA+  +K +    A+ DC ++I++
Sbjct: 557 DTFKSGQYAEALELYSEGLDICPLKYVQQRSVMLSNRAACRIKKEDYQKAVGDCTKSIDL 378

Query: 177 NPDSAQPYKWRGKAHRLLGHWEEAAHD 203
           NP   + Y  R  A+  L   ++A  D
Sbjct: 377 NPAYIKAYFRRADAYEKLEKLDDALKD 297

 Score = 32.7 bits (73), Expect = 0.21,   Method: Compositional matrix adjust.
 Identities = 17/50 (34%), Positives = 30/50 (60%)
 Frame = -2

Query: 128 ELQKAIDLFTDAIKLNPRLAILYAKRASVFVKLQKPNAAIRDCDRAIEIN 177
           + QKA+   T +I LNP     Y +RA  + KL+K + A++D  + +E++
Sbjct: 422 DYQKAVGDCTKSIDLNPAYIKAYFRRADAYEKLEKLDDALKDHRQVVEMD 273
>37348
          Length = 116

 Score = 37.7 bits (86), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 16/25 (64%), Positives = 20/25 (80%)
 Frame = -2

Query: 315 LNEILSDPEVLAAMQDPEVMVAFQD 339
           +  +L DPE+LAA+QDPEV  AFQD
Sbjct: 76  MTTLLQDPELLAALQDPEVSAAFQD 2
>03857
          Length = 1696

 Score = 30.4 bits (67), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 15/47 (31%), Positives = 26/47 (55%)
 Frame = +1

Query: 154 ASVFVKLQKPNAAIRDCDRAIEINPDSAQPYKWRGKAHRLLGHWEEA 200
           A+  +KL K N A+  C   +E +PD+++    +G+AH     +E A
Sbjct: 643 AACCLKLNKYNEALEYCQEVLEADPDNSKAQYRQGQAHAGNKDYETA 783
>06534
          Length = 1176

 Score = 30.4 bits (67), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 12/19 (63%), Positives = 16/19 (84%)
 Frame = -1

Query: 315 LNEILSDPEVLAAMQDPEV 333
           +  +L DPE+LAA+QDPEV
Sbjct: 60  MTTLLQDPELLAALQDPEV 4
>23484
          Length = 1647

 Score = 30.0 bits (66), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 19/52 (36%), Positives = 26/52 (50%), Gaps = 4/52 (7%)
 Frame = +1

Query: 132 AIDLFTDAIKLNP--RL--AILYAKRASVFVKLQKPNAAIRDCDRAIEINPD 179
           A+D + + IK N   RL  A+LY  RA+    L    +A  DC  A +  PD
Sbjct: 556 AVDNYXEGIKSNSPQRLQNAVLYTNRAAAHFHLGNYRSAFNDCFAARKFKPD 711
>20921
          Length = 649

 Score = 29.3 bits (64), Expect = 2.8,   Method: Compositional matrix adjust.
 Identities = 17/65 (26%), Positives = 29/65 (44%), Gaps = 7/65 (10%)
 Frame = +3

Query: 139 AIKLNPRLAILYAKRASVFVKLQKPNAAIRDCDRAI-------EINPDSAQPYKWRGKAH 191
           ++K      I  +K A  F +L K N  +  C+  I       + +P + + + W G AH
Sbjct: 276 SVKHTSHCTIECSKSACSFFRL-KSNRRVNKCEADIKPSCMARQSSPSTLREHCWSGSAH 452

Query: 192 RLLGH 196
           R + H
Sbjct: 453 RQISH 467
>13998
          Length = 1075

 Score = 28.9 bits (63), Expect = 3.7,   Method: Compositional matrix adjust.
 Identities = 15/59 (25%), Positives = 30/59 (50%)
 Frame = +1

Query: 166 AIRDCDRAIEINPDSAQPYKWRGKAHRLLGHWEEAAHDLALACKLDYDEDASAMLREVQ 224
           A+ DC+R +++N    +    R + +  L  +EEA  D   A +L+   +   +LR+ +
Sbjct: 1   AVADCNRVLDLNSQYLKALLLRARCNNDLEKFEEAVADYETALQLEKTPEIKRLLRDAK 177
>18476
          Length = 908

 Score = 27.3 bits (59), Expect = 9.8,   Method: Compositional matrix adjust.
 Identities = 20/59 (33%), Positives = 27/59 (45%)
 Frame = +2

Query: 101 ENAEITEEMMDEANEKKGAAIEALNDGELQKAIDLFTDAIKLNPRLAILYAKRASVFVK 159
           E+AE   E MDE NE+ G A     DG+  K  D      K+    +I Y    ++F K
Sbjct: 62  EDAEHGTEDMDEINEENGYAKMVTEDGKEDKYTDDQKAVFKMKHCASIPYCYYGTLFDK 238
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|7949018|ref|NP_058022.1| cell division cycle 37
homolog [Mus musculus]
         (379 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

08794                                                                 214   7e-56
36915                                                                  86   3e-17
15931                                                                  30   2.2  
32402                                                                  29   4.0  
>08794
          Length = 1813

 Score =  214 bits (544), Expect = 7e-56,   Method: Compositional matrix adjust.
 Identities = 99/159 (62%), Positives = 124/159 (77%)
 Frame = +2

Query: 188 ANYLVIWCIDLEVEEKCALMEQVAHQTMVMQFILELAKSLKVDPRACFRQFFTKIKTADH 247
           ANYLVIWCIDLEVEEK  LM+ V+HQT+VMQFILELAKSL+ DPR+C R FF++IK A+ 
Sbjct: 2   ANYLVIWCIDLEVEEKHDLMKHVSHQTIVMQFILELAKSLEQDPRSCVRAFFSRIKLAEK 181

Query: 248 QYMEGFKYELEAFKERVRGRAKLRIXXXXXXXXXXXXXXRLGPGGLDPVEVYESLPEELQ 307
           QYM+ F  EL +F+ERV+GRA++RI              RLGPGGLDPVEV ESLPE +Q
Sbjct: 182 QYMDAFNDELNSFRERVKGRAQVRIEEAMKEYEEEEKQKRLGPGGLDPVEVMESLPENMQ 361

Query: 308 KCFDVKDVQMLQDAISKMDPTDAKYHMQRCIDSGLWVPN 346
           KCF+ +D+ +LQ A+ +M   +A+YH++RCIDSGLWVPN
Sbjct: 362 KCFESRDIGLLQQAVLEMPKEEAEYHIKRCIDSGLWVPN 478
>36915
          Length = 364

 Score = 85.9 bits (211), Expect = 3e-17,   Method: Compositional matrix adjust.
 Identities = 45/74 (60%), Positives = 61/74 (82%)
 Frame = +1

Query: 2   VDYSVWDHIEVSDDEDETHPNIDTASLFRWRHQARVERMEQFQKEKEELDRGCRECKRKV 61
           ++YS WDHIE+SDDED+THPNIDT SL+RWRHQARVERME  +K+KE  ++  +  ++K+
Sbjct: 85  INYSKWDHIEISDDEDDTHPNIDTPSLYRWRHQARVERMEDAKKKKETFEKEKQSHQQKM 264

Query: 62  AECQRKLKELEVAE 75
            E ++KLKE EV+E
Sbjct: 265 NEIKQKLKE-EVSE 303
>15931
          Length = 447

 Score = 29.6 bits (65), Expect = 2.2,   Method: Compositional matrix adjust.
 Identities = 17/45 (37%), Positives = 22/45 (48%), Gaps = 7/45 (15%)
 Frame = -3

Query: 27  SLFRWR------HQARVERMEQFQKEKEELDRGCREC-KRKVAEC 64
           S+FRWR      H+ R  R    +++   LD GC  C  RK A C
Sbjct: 223 SVFRWRKSECCRHEPRRPRTACGRRDGAWLDAGCSAC*PRKTASC 89
>32402
          Length = 1844

 Score = 28.9 bits (63), Expect = 4.0,   Method: Compositional matrix adjust.
 Identities = 17/50 (34%), Positives = 30/50 (60%)
 Frame = -1

Query: 77  DGQVELERLRAEAQQLRKEERSWEQKLEDMRKKEKNMPWNVDTLSKDGFS 126
           +G ++ ERL   +Q++ K++++   KL+   K  KN+  N  TL+K  FS
Sbjct: 794 NGNLK*ERLHLASQKIEKKKKTLYCKLKFKTKTNKNLQQNA-TLTKKSFS 648
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|18700004|ref|NP_570934.1| acetyl-Coenzyme A
acyltransferase 1 [Mus musculus]
         (424 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

19628                                                                 213   1e-55
02902                                                                 174   7e-44
13792                                                                 105   3e-23
19453                                                                  82   3e-16
17665                                                                  78   7e-15
06343                                                                  33   0.20 
>19628
          Length = 537

 Score =  213 bits (542), Expect = 1e-55,   Method: Compositional matrix adjust.
 Identities = 101/125 (80%), Positives = 113/125 (90%)
 Frame = -2

Query: 299 PILGVLRSYAVVGVPPDVMGIGPAYAIPAALQKAGLTVNDIDIFEINEAFASQAVYCVEK 358
           P+LGVLRS+AV G PPD+MGIGPA AIP AL+KAGLTVNDIDIFEINEAFASQA YCVEK
Sbjct: 536 PVLGVLRSFAVTGCPPDIMGIGPAVAIPEALKKAGLTVNDIDIFEINEAFASQARYCVEK 357

Query: 359 LGIPAEKVNPLGGAIALGHPLGCTGARQVVTLLNELKRRGRRAYGVVSMCIGTGMGAAAV 418
           LGIP ++VNP GGAIALGHPLGCTGAR + TLL+E+KRRG+R  GVVSMC+GTGMGAAA+
Sbjct: 356 LGIPMDRVNPKGGAIALGHPLGCTGARMIGTLLHEMKRRGKRGMGVVSMCMGTGMGAAAI 177

Query: 419 FEYPG 423
           FEY G
Sbjct: 176 FEYEG 162
>02902
          Length = 2008

 Score =  174 bits (440), Expect = 7e-44,   Method: Compositional matrix adjust.
 Identities = 107/241 (44%), Positives = 137/241 (56%)
 Frame = +2

Query: 180 PMGMTSENVAERFGISRQKQDDFXXXXXXXXXXXXXRGCFRAEIVPVTTTVLDDKGDKKT 239
           PMGMT+EN+A+++ ISRQ  D                G F  EI P+       KG K  
Sbjct: 194 PMGMTAENLAQQYNISRQDCDQHAFQTQXRWQEAQKAGKFDDEIYPIKV-----KGKKGP 358

Query: 240 ITVSQDEGVRPSTTMQGLAKLKPAFKDGGSTTAGNSSQVSDGAAAVLLARRSKAEELGLP 299
              + DE  R  T ++ LAKL P FK  G+ TAGN+S + DGAAA++LA     +   L 
Sbjct: 359 EDFAVDEHPR-VTPVEVLAKLPPVFKKDGTVTAGNASGICDGAAALILASEEAVKANNLT 535

Query: 300 ILGVLRSYAVVGVPPDVMGIGPAYAIPAALQKAGLTVNDIDIFEINEAFASQAVYCVEKL 359
            L  L SY   G  P VMGIGPA A  AAL+KAG TV D+D+ E+NEAFA Q +   ++L
Sbjct: 536 PLARLVSYGYAGCDPKVMGIGPAPASRAALEKAGKTVQDMDVVEVNEAFAPQFLAVAKEL 715

Query: 360 GIPAEKVNPLGGAIALGHPLGCTGARQVVTLLNELKRRGRRAYGVVSMCIGTGMGAAAVF 419
           G+   + N  GGAIALGHPLG +GAR    L++E+ RR    Y + S CIG G G   + 
Sbjct: 716 GLDNARTNVNGGAIALGHPLGASGARITSNLVHEI-RRSNLKYAMGSACIGGGQGITVIL 892

Query: 420 E 420
           E
Sbjct: 893 E 895
>13792
          Length = 1330

 Score =  105 bits (262), Expect = 3e-23,   Method: Compositional matrix adjust.
 Identities = 66/161 (40%), Positives = 89/161 (55%), Gaps = 19/161 (11%)
 Frame = +3

Query: 256 GLAKLKPAF-KDGGSTTAGNSSQVSDGAAAVLLARRSKAEELGLPILGVLRSYAVVGV-P 313
           G  K K AF K  G+ TA N+S ++DGA+A L+    KA  +G   L  LR +  V   P
Sbjct: 831 GHGKTKAAFIKPHGTVTAANASFLTDGASACLIMSEEKALAMGYKPLAYLRDFLYVAQDP 1010

Query: 314 PDVMGIGPAYAIPAALQKAGLTVNDIDIFEINEAFASQAVYCVEKL-------------- 359
            D + +GPAYA P  L KAGLT++DI +FE +EAFA Q +  ++ L              
Sbjct: 1011KDQLLLGPAYATPRILNKAGLTMSDISVFEYHEAFAGQILANMKALDSDWFGTNMMGLQG 1190

Query: 360 --GIPA-EKVNPLGGAIALGHPLGCTGARQVVTLLNELKRR 397
             G PA +K+N  GG+++LGHP G TG R V T  N L + 
Sbjct: 1191KAGAPALDKLNLWGGSLSLGHPFGATGVRLVTTAANRLHKE 1313
>19453
          Length = 633

 Score = 82.4 bits (202), Expect = 3e-16,   Method: Compositional matrix adjust.
 Identities = 53/123 (43%), Positives = 76/123 (61%), Gaps = 2/123 (1%)
 Frame = -3

Query: 218 CFRAEIVPVTTTVLDDKGDKKTITVSQDEGVRPSTTMQGLAKLKPAF-KDG-GSTTAGNS 275
            F AEIVPV+      +       V +DE  R   +++GL KL+PAF KDG G+ TAGN+
Sbjct: 355 AFDAEIVPVSI-----QSRTGVTEVKKDEFPRAGCSIEGLQKLRPAFIKDGSGTVTAGNA 191

Query: 276 SQVSDGAAAVLLARRSKAEELGLPILGVLRSYAVVGVPPDVMGIGPAYAIPAALQKAGLT 335
           S ++DGAAAV++   ++A+   L  L  + S+A  GV P +MG GP  A+ AA++KAG T
Sbjct: 190 SGINDGAAAVVVMSATEAKARSLQPLVRIVSWAQAGVDPSIMGTGPIPAVRAAVEKAGWT 11

Query: 336 VND 338
           V +
Sbjct: 10  VGE 2
>17665
          Length = 477

 Score = 77.8 bits (190), Expect = 7e-15,   Method: Compositional matrix adjust.
 Identities = 40/73 (54%), Positives = 54/73 (73%)
 Frame = -3

Query: 344 INEAFASQAVYCVEKLGIPAEKVNPLGGAIALGHPLGCTGARQVVTLLNELKRRGRRAYG 403
           +NEAFA+Q++  V+ LG    KVN  GGAIALGHP+G +GAR +VTLL+ +K RG +  G
Sbjct: 475 LNEAFAAQSLAVVKDLGCDPAKVNVNGGAIALGHPIGASGARILVTLLHSMKHRGAK-KG 299

Query: 404 VVSMCIGTGMGAA 416
           V ++C+G GMG A
Sbjct: 298 VAALCVGGGMGIA 260
>06343
          Length = 1647

 Score = 33.1 bits (74), Expect = 0.20,   Method: Compositional matrix adjust.
 Identities = 31/118 (26%), Positives = 48/118 (40%), Gaps = 6/118 (5%)
 Frame = +3

Query: 43   GRRTPIGRASRGGFKNTTPDELLSAVLTAVLQDVRLKPEQLG------DISVGNVLEPGA 96
            GRR P+GR S G F +  P  L S  + + L+  R  P  +G      D+ V        
Sbjct: 1182 GRRVPLGRGSAGLFLSRCPGPLASPHMPSALEVARQ*PMIMGAVQDEVDVWVLTTTRLDV 1361

Query: 97   GAVMARIAQFLSGIPETVPLSTVNRQCSSGLQAVANIAGGIRNGSYDIGMACGVESMS 154
               +  +  +  G         +NR+  +GL    +   G+R GS  +G   GV+  S
Sbjct: 1362 YRFLVHVHDWQKG--------QLNRERRAGLHVDIDATLGVRVGSGVLGRQRGVDHPS 1511
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|150456419|ref|NP_031868.2| DEAH (Asp-Glu-Ala-His) box
polypeptide 9 [Mus musculus]
         (1383 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

19948                                                                 214   2e-55
19545                                                                 212   1e-54
17966                                                                 187   3e-47
09272                                                                 145   1e-34
33732                                                                 140   3e-33
12784                                                                 129   9e-30
03659                                                                 114   2e-25
35764                                                                  77   4e-14
18403                                                                  76   1e-13
20747                                                                  52   1e-06
35632                                                                  51   3e-06
>19948
          Length = 466

 Score =  214 bits (544), Expect = 2e-55,   Method: Compositional matrix adjust.
 Identities = 99/128 (77%), Positives = 115/128 (89%)
 Frame = +1

Query: 629 LNEKETPFELIEALLKYIETLNVPGAVLVFLPGWNLIYTMQKHLENNSHFGSHRYQILPL 688
           L EKE  FEL+EALL+YI+ L +PGAVL FLPGW+LI+ +Q+HL+ +  FGS +Y ILPL
Sbjct: 61  LPEKEISFELVEALLRYIQGLGIPGAVLFFLPGWSLIFMIQRHLQMSPEFGSSKYCILPL 240

Query: 689 HSQIPREEQRKVFDPVPDGVTKVILSTNIAETSITINDVVYVIDSCKQKVKLFTAHNNMT 748
           HSQIPREEQRKVF+PVPDGVTK+ILSTNIAETS+TINDVVYVIDSCK K+KLFT+HNNMT
Sbjct: 241 HSQIPREEQRKVFEPVPDGVTKIILSTNIAETSVTINDVVYVIDSCKVKMKLFTSHNNMT 420

Query: 749 NYATVWAS 756
           NYATVWAS
Sbjct: 421 NYATVWAS 444
>19545
          Length = 519

 Score =  212 bits (539), Expect = 1e-54,   Method: Composition-based stats.
 Identities = 91/155 (58%), Positives = 115/155 (74%)
 Frame = +2

Query: 436 RAAECNIVVTQPRRISXXXXXXXXXXXXXXXPGKSCGYSVRFESILPRPHASIMFCTVGV 495
           R A CNI+VTQPRRIS                G S GYSVRFE+++PRP+ ++++CTVG 
Sbjct: 2   RGAFCNIIVTQPRRISAVSIAERVAEERSEMLGNSVGYSVRFETVMPRPYGAMLYCTVGT 181

Query: 496 LLRKLEAGIRGISHVIVDEIHERDINTDFXXXXXXXXXXAYPEVRIVLMSATIDTTMFCE 555
           LLRKLE G+RG+SHVIVDEIHERDINTDF          AYP++R++LMSAT+DTT+F +
Sbjct: 182 LLRKLEGGLRGVSHVIVDEIHERDINTDFLLVLLRDMVRAYPDLRVLLMSATVDTTLFTD 361

Query: 556 YFFNCPIIEVYGRTFPVQEYFLEDCIQMTQFIPPP 590
           YF +C ++EVYGR +PVQEY+LEDCIQM  F+P P
Sbjct: 362 YFGSCTVVEVYGRVYPVQEYYLEDCIQMLNFVPAP 466
>17966
          Length = 424

 Score =  187 bits (474), Expect = 3e-47,   Method: Compositional matrix adjust.
 Identities = 91/139 (65%), Positives = 112/139 (80%)
 Frame = -1

Query: 759 NLEQRKGRAGRVRPGFCFHLCSRARFDRLETHMTPEMFRTPLHEIALSIKLLRLGGIGQF 818
           NLEQR+GRAGRVRPGF   + SR   +    H + ++   PLHE+ALSIKLLRLG I  F
Sbjct: 424 NLEQRRGRAGRVRPGFLSIVQSRPLRETGPAHNSGDIPH-PLHELALSIKLLRLGPISGF 248

Query: 819 LAKAIEPPPLDAVIEAEHTLRELDALDANDELTPLGRILAKLPIEPRFGKMMIMGCIFYV 878
           L+ A+EPPP+DAV+EAE TLR + ALD+NDELTPLGRILA++PIEP  GKM+I GCIFY+
Sbjct: 247 LSXAVEPPPIDAVVEAEATLRSMHALDSNDELTPLGRILARMPIEPHLGKMIIYGCIFYI 68

Query: 879 GDAVCTISAATCFPEPFIS 897
           GDA+CTI+A+T FPEPFI+
Sbjct: 67  GDAMCTIAASTTFPEPFIT 11
>09272
          Length = 890

 Score =  145 bits (365), Expect = 1e-34,   Method: Compositional matrix adjust.
 Identities = 92/282 (32%), Positives = 141/282 (50%), Gaps = 6/282 (2%)
 Frame = +2

Query: 691 QIPREEQRKVFDPVPDGVTKVILSTNIAETSITINDVVYVIDSCKQKVKLFTAHNNMTNY 750
           ++P E Q ++F+P P G  KV+++TNIAETS+TIN + YV+D    K  ++ +   M   
Sbjct: 53  RLPSEMQTRIFEPAPPGSRKVVIATNIAETSLTINGIYYVVDPGFVKQNVYNSKTGMDQL 232

Query: 751 ATVWASKTNLEQRKGRAGRVRPGFCFHLCS-RARFDRLETHMTPEMFRTPLHEIALSIKL 809
                S+   +QR GRAGR  PG C+ L + RA  D +     PE+ RT L    LS+K 
Sbjct: 233 IVTPISQAQAKQRAGRAGRTGPGKCYRLYTERAYRDEMLPTNVPEIQRTNLASTVLSLKA 412

Query: 810 LRLGGIGQFLA-KAIEPPPLDAVIEAEHTLRELDALDANDELTPLGRILAKLPIEPRFGK 868
           +   GI   LA   ++ PP+  +I A   L  L ALD    LT LGR +A+ P+EP   K
Sbjct: 413 M---GINDLLAFDFMDSPPMQTLISAMEQLHALSALDDEGLLTRLGRRMAEFPLEPMLSK 583

Query: 869 MMIMGCIFYVGDAVCTISAATCFPEPFISEGKRLGYIHRNFAGNRF----SDHVALLSVF 924
           M+IM       D + TI +       F     +     +  A  +F     DH+ LLSV+
Sbjct: 584 MLIMSVHLACSDEILTIVSMLSVQNVFYRPKDKQALADQKKA--KFHQPEGDHLTLLSVY 757

Query: 925 QAWDDARMSGEEAEIRFCEQKRLNMATLRMTWEAKVQLKEIL 966
            +W + + S       +C +  + + TL+   + + Q+  I+
Sbjct: 758 NSWKNNKFSSP-----WCYENFVQIRTLKRAQDVRKQMLGIM 868
>33732
          Length = 604

 Score =  140 bits (354), Expect = 3e-33,   Method: Compositional matrix adjust.
 Identities = 79/191 (41%), Positives = 115/191 (60%), Gaps = 13/191 (6%)
 Frame = -1

Query: 155 EEQEVQATLESE-EVDLNAGLHGNWTLENAKARLNQYFQKEKIQGEYKYTQVGPDHNRSF 213
           E++E++  +E E +V++   ++GNWT+E AK++L+QY Q  +IQ +YKY+ VGPB++RS 
Sbjct: 586 EDEEMKVDVEMEVDVEMKIDMNGNWTVETAKSQLHQYLQTNRIQTDYKYSVVGPBYDRSI 407

Query: 214 IAEMTIYIKQLGRRIFAREHGSNKKLAAQSCALSLVRQLYHLGVIEAYSGLTKKKEGERV 273
           +AEM  ++KQ  ++I AREHGSNK+ A++SCALSLVRQL+HL  IEAY GL KK++   +
Sbjct: 406 VAEMGFFVKQXXQQIHAREHGSNKQTASKSCALSLVRQLFHLKAIEAYGGLKKKRKDADL 227

Query: 274 EPYKVFL-SPXXXXXXXXXXXXXXXXIVPPPVDPSMPV-----------ILNIGKLAHFE 321
            PY+V + S                 I P  V P               +L    L  FE
Sbjct: 226 PPYEVAVHSDLLQQVDQCLNTWGIQPITPNDVQPKSEEGEEEDESPRQSLLVKESLDEFE 47

Query: 322 PSQRQNAVGVV 332
           P+ R+ A GVV
Sbjct: 46  PAPRRMAPGVV 14
>12784
          Length = 2199

 Score =  129 bits (324), Expect = 9e-30,   Method: Compositional matrix adjust.
 Identities = 83/264 (31%), Positives = 143/264 (54%), Gaps = 7/264 (2%)
 Frame = -1

Query: 710  KVILSTNIAETSITINDVVYVIDSCKQKVKLFTAHNNMTNYATVWASKTNLEQRKGRAGR 769
            KV++STNIAETS+TI+ VV+VID    K K++     + +      SK + +QR GRAGR
Sbjct: 2196 KVVVSTNIAETSLTIDGVVFVIDPGFAKQKVYNPRIRVESLLVTAISKASAQQRAGRAGR 2017

Query: 770  VRPGFCFHLCS-RARFDRLETHMTPEMFRTPLHEIALSIKLLRLGGIGQFLAKAIEPPPL 828
             RPG CF L + +A    ++ +  PE+ R+ L  + L +K L +  +  F    ++PP  
Sbjct: 2016 TRPGKCFRLYTEKAYTQEMQENTYPEILRSNLGSVVLQLKKLGIDDLVHF--DFMDPPAP 1843

Query: 829  DAVIEAEHTLRELDALDANDELTPLGRILAKLPIEPRFGKMMIMGCIFYVGDAVCTISAA 888
            + ++ A   L  L  LD + ELT LG ++A+ P++P+  KM+I  C     + + +I++ 
Sbjct: 1842 ETLMRALELLNYLAGLDDDGELTELGSMMAEFPLDPQLAKMVIASCDSNCSNEILSITSM 1663

Query: 889  TCFPEPFI--SEGKRLGYIHRNFAGNRFS----DHVALLSVFQAWDDARMSGEEAEIRFC 942
               P+ F+  +E K+      + A  RF+    DH+ LL+V+ A+   + + E+ +  +C
Sbjct: 1662 LSVPQCFVRPTEAKKAA----DEAKMRFAHIDGDHLTLLNVYHAF---KQNHEDPQ--WC 1510

Query: 943  EQKRLNMATLRMTWEAKVQLKEIL 966
                +N  +L+     + QL  I+
Sbjct: 1509 YDNFINYRSLKSADNVRQQLARIM 1438
>03659
          Length = 1566

 Score =  114 bits (286), Expect = 2e-25,   Method: Compositional matrix adjust.
 Identities = 61/187 (32%), Positives = 101/187 (54%), Gaps = 2/187 (1%)
 Frame = -1

Query: 381 QSVLQERELLPVKKFEAEILEAISSNSVVIIRGATGCGKTTQVPQYILDDFIQNDRAAEC 440
           +S+L++R+ LP+ K + E+L+A+  N ++I+ G TG GKTTQ+ QY+     ++      
Sbjct: 546 KSILEQRQGLPIYKLKDELLKAVHDNQILIVIGETGSGKTTQITQYL----AESGYTTRG 379

Query: 441 NIVVTQPRRISXXXXXXXXXXXXXXXPGKSCGYSVRFESILPRPHASIMFCTVGVLLRK- 499
            I  TQPRR++                G+  GY++RFE     P   I + T G+LLR+ 
Sbjct: 378 KIGCTQPRRVAAMSVAKRVSEEFGCRLGQEVGYTIRFEDCT-SPETKIKYMTDGMLLREC 202

Query: 500 -LEAGIRGISHVIVDEIHERDINTDFXXXXXXXXXXAYPEVRIVLMSATIDTTMFCEYFF 558
            ++  +   S V++DE HER I+TD             P++++++ SAT+D   F +YFF
Sbjct: 201 LIDRDLMQYSIVMLDEAHERTIHTDVLFGLLKQAVKKRPDLKLIVTSATLDAVKFSQYFF 22

Query: 559 NCPIIEV 565
             PI  +
Sbjct: 21  EAPIFTI 1
>35764
          Length = 238

 Score = 77.4 bits (189), Expect = 4e-14,   Method: Compositional matrix adjust.
 Identities = 32/50 (64%), Positives = 44/50 (88%)
 Frame = -1

Query: 30  NRQKFMCEVRVEGFNYAGMGNSTNKKDAQSNAARDFVNYLVRINEVKSEE 79
           +RQ+F CE+RVEG +Y G+GNST+KKDAQ+NAARDFVN+LVRI ++  ++
Sbjct: 238 HRQRFKCELRVEGLDYVGVGNSTSKKDAQANAARDFVNFLVRIGKMDGKD 89
>18403
          Length = 434

 Score = 75.9 bits (185), Expect = 1e-13,   Method: Compositional matrix adjust.
 Identities = 40/119 (33%), Positives = 68/119 (57%)
 Frame = +2

Query: 777 HLCSRARFDRLETHMTPEMFRTPLHEIALSIKLLRLGGIGQFLAKAIEPPPLDAVIEAEH 836
            L + + ++  E + TPE+ R PL  + L +  + L  + +F    IEPP L  +  +  
Sbjct: 2   RLYAESDYNEFEAYSTPEIQRVPLDSLVLQLISMGLPNVRKF--PFIEPPDLSTIENSVR 175

Query: 837 TLRELDALDANDELTPLGRILAKLPIEPRFGKMMIMGCIFYVGDAVCTISAATCFPEPF 895
            L+E  AL  ++ LT +G++L+ LP++   GKM+IMG IF++ D + +I+AA     PF
Sbjct: 176 FLKEQGALAGDESLTAIGQMLSMLPVDVVIGKMLIMGSIFHMVDPILSIAAAMSVQSPF 352
>20747
          Length = 444

 Score = 52.4 bits (124), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 42/141 (29%), Positives = 66/141 (46%), Gaps = 8/141 (5%)
 Frame = +1

Query: 417 CGKTTQVPQYILDDFIQNDRAAECNIVVTQPRRISXXXXXXXXXXXXXXXPGKSCGYSVR 476
            GKTTQVPQ++ +    +       I VT+PRR++                 +   Y +R
Sbjct: 1   SGKTTQVPQFLYEAGYAHKGGM---IGVTEPRRVAAISMSQRVAEEMNLT-SREVSYQIR 168

Query: 477 FE-SILPRPHASIMFCTVGVLLRKLEAG--IRGISHVIVDEIHERDINTDFXXXXXXXXX 533
           +E ++ P  H  I F T GVLLR+++    +   S +I+DE HER + TD          
Sbjct: 169 YEGNVTPDTH--IKFMTDGVLLREIQQDFVLSKYSVIILDEAHERSVFTDILIGLLSRIA 342

Query: 534 -----XAYPEVRIVLMSATID 549
                     +++V+MSAT+D
Sbjct: 343 PYRIKKNLSPLKLVIMSATLD 405
>35632
          Length = 627

 Score = 51.2 bits (121), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 29/91 (31%), Positives = 52/91 (57%), Gaps = 6/91 (6%)
 Frame = +1

Query: 847 NDELTPLGRILAKLPIEPRFGKMMIMGCIFYVGDAVCTISAA----TCFPEPFISEGKRL 902
           + +LT +GR++A LP++ R GK+MI+G +F + +    I AA    + F  PF S   RL
Sbjct: 109 DGDLTFVGRVMADLPVDIRIGKLMILGYVFGLLEECIIIGAALSLKSIFATPFKS---RL 279

Query: 903 -GYIHR-NFAGNRFSDHVALLSVFQAWDDAR 931
             ++H+  ++    SD  A+L  ++ W+  +
Sbjct: 280 EAFMHKYQWSSGSLSDCQAILHAYRVWEKCK 372
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|158853992|ref|NP_075608.2| enolase 1, alpha
non-neuron [Mus musculus]
         (434 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

09637                                                                 212   2e-55
26158                                                                 124   8e-29
33905                                                                  58   8e-09
36511                                                                  28   6.4  
09576                                                                  28   9.9  
>09637
          Length = 1627

 Score =  212 bits (539), Expect = 2e-55,   Method: Compositional matrix adjust.
 Identities = 97/126 (76%), Positives = 110/126 (87%)
 Frame = +1

Query: 306 KFTASAGIQVVGDDLTVTNPKRIAKAASEKSCNCLLLKVNQIGSVTESLQACKLAQSNGW 365
           K T++   Q+VGDDL VTNPKR+     +K+CN LLLKVNQIGSVTE++ ACK++Q  GW
Sbjct: 1   KMTSATDCQIVGDDLLVTNPKRVQTGIEKKACNALLLKVNQIGSVTEAIDACKMSQKEGW 180

Query: 366 GVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQILRIEEELGSKAKFAG 425
           GVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQ+LRIEEELG KAK+AG
Sbjct: 181 GVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLLRIEEELGGKAKYAG 360

Query: 426 RSFRNP 431
            +FRNP
Sbjct: 361 ENFRNP 378
>26158
          Length = 431

 Score =  124 bits (311), Expect = 8e-29,   Method: Compositional matrix adjust.
 Identities = 60/98 (61%), Positives = 75/98 (76%)
 Frame = -2

Query: 3   ILRIHAREIFDSRGNPTVEVDLYTAKGLFRAAVPSGASTGIYEALELRDNDKTRFMGKGV 62
           I +IHAR+IFDSRGNPTVEVDL T KGLFRAAVPSGASTGIYEA+ELRD D   +  KGV
Sbjct: 295 IKKIHARQIFDSRGNPTVEVDLTTDKGLFRAAVPSGASTGIYEAVELRDGDPKCYHKKGV 116

Query: 63  SQAVEHINKTIAPALVSKKVNVVEQEKIDKLMIEMDGT 100
             AV ++N  IA AL+   + V  Q ++D+ ++++DGT
Sbjct: 115 LTAVSNVNDKIAQALIESGIPVQNQREVDEFLMKLDGT 2
>33905
          Length = 560

 Score = 57.8 bits (138), Expect = 8e-09,   Method: Compositional matrix adjust.
 Identities = 27/61 (44%), Positives = 43/61 (70%)
 Frame = +2

Query: 364 GWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQILRIEEELGSKAKF 423
           G  ++++  +GE++D FIADL V +    IK GAP R ER++K+N++L+IE EL + +K 
Sbjct: 272 GNQIILNACAGESQDDFIADLAVAMNVRFIKIGAPNRGERISKFNRLLQIEAELEASSKL 451

Query: 424 A 424
           A
Sbjct: 452 A 454
>36511
          Length = 169

 Score = 28.1 bits (61), Expect = 6.4,   Method: Composition-based stats.
 Identities = 13/34 (38%), Positives = 21/34 (61%)
 Frame = -2

Query: 137 LAGNPEVILPVPAFNVINGGSHAGNKLAMQEFMI 170
           L  N  +ILP+ A NV N G++   +L+  +FM+
Sbjct: 114 LKDNINIILPITAHNVANIGNNPMKELS*TQFMV 13
>09576
          Length = 2266

 Score = 27.7 bits (60), Expect = 9.9,   Method: Compositional matrix adjust.
 Identities = 12/30 (40%), Positives = 18/30 (60%)
 Frame = -2

Query: 230  AIAKAGYTDQVVIGMDVAASEFYRSGKYDL 259
            A+ K  YTD+V IG +   +  Y + KYD+
Sbjct: 1005 ALLKFVYTDEVQIGPETVMTTLYAAKKYDV 916
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|28076907|ref|NP_080917.1| WD repeat domain 56 [Mus
musculus]
         (777 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

22017                                                                 213   2e-55
10313                                                                 181   9e-46
02147                                                                  50   4e-06
13278                                                                  45   2e-04
27681                                                                  36   5e-04
00561                                                                  40   0.004
19498                                                                  40   0.004
07781                                                                  39   0.006
12960                                                                  38   0.017
19949                                                                  38   0.018
16105                                                                  37   0.036
03156                                                                  37   0.037
01768                                                                  37   0.044
21921                                                                  36   0.058
03395                                                                  36   0.068
31474                                                                  35   0.16 
01327                                                                  34   0.23 
12574                                                                  34   0.23 
30108                                                                  34   0.25 
10264                                                                  32   0.66 
01598                                                                  32   0.74 
38177                                                                  32   0.79 
31384                                                                  32   0.83 
02960                                                                  32   0.85 
38362                                                                  32   0.93 
03044                                                                  30   3.1  
11915                                                                  30   3.4  
37180                                                                  30   4.1  
24037                                                                  29   5.8  
15337                                                                  28   9.8  
>22017
          Length = 531

 Score =  213 bits (543), Expect = 2e-55,   Method: Compositional matrix adjust.
 Identities = 87/169 (51%), Positives = 130/169 (76%)
 Frame = +1

Query: 441 FLFEASTGKPLGDGKLLSHKNEISEIALDQKGLTNDRKIAFIDKNRDLYITSVKRFGKEE 500
           ++F+A TGK +GDGK ++HK E+ E+ALDQ G   +RK+A IDKNRDL++TSV+ FG E 
Sbjct: 25  YIFDAQTGKAMGDGKPITHKVEVLEVALDQCGPATERKLAIIDKNRDLFLTSVRIFGTER 204

Query: 501 QIIKLGTMVHTLAWCDTCNILCGIQDTRFTVWYYPNTIYVDRDILPKTLYERDASEYSKN 560
           +  KL TM+H + W D  N+L  + D +  VWYYPN +YVD ++LPKT+ E+D SE+ K+
Sbjct: 205 KSTKLATMIHMMTWNDETNMLAAMTDGKIFVWYYPNAVYVDAELLPKTVAEKDTSEFGKS 384

Query: 561 PHIVSFVGNQVTIRRADGSLVHISISPYPAILHEYVSSSKWEEAVRLCR 609
           P +++F+G+ + +RR +GSL+  +I+PYPA+LH +V++S+WE+AVRLCR
Sbjct: 385 PQLLNFIGSHLILRRVEGSLISTTIAPYPAVLHSFVAASRWEDAVRLCR 531
>10313
          Length = 689

 Score =  181 bits (459), Expect = 9e-46,   Method: Compositional matrix adjust.
 Identities = 80/136 (58%), Positives = 115/136 (84%)
 Frame = +3

Query: 628 RDMVTAEIAYAAVGEIDKVRYINAIKDLPSRESKMAHILMFSGNIQEAETVLLQAGLVYQ 687
           +D+ TAE+AYAA+ E++KV++I+ IKD+P +E++ A + +  GN  +AE +LLQAGL+++
Sbjct: 6   KDLNTAEVAYAAIKEVEKVQFISNIKDIPVKEARNAEMALLCGNYNDAEAILLQAGLIFR 185

Query: 688 AIQININLYNWERALELAVKYKTHVDTVLAYRQKFLDTFGKQETNKRYLQYAEGLQIDWE 747
           A+ +NI LYNW+RALELAVK+KTHVDTVL YR+K+L  F ++ETNKR+ QY+EG++IDWE
Sbjct: 186 AVLLNIQLYNWDRALELAVKHKTHVDTVLGYRKKYLKRFDRKETNKRFTQYSEGIEIDWE 365

Query: 748 KIKAKIEMEITKERDR 763
           KI++KIEME  KER+R
Sbjct: 366 KIESKIEMEYQKERER 413
>02147
          Length = 1547

 Score = 50.1 bits (118), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 42/168 (25%), Positives = 73/168 (43%), Gaps = 3/168 (1%)
 Frame = +2

Query: 100 KSVEAHCGAVLAGRWNYEGTALVTVGEDGQVKIWSKTGMLRSTLAQQGTPVYSVAWGPDS 159
           KS   H   +    +  +G  +++  +D  V++WS             TP  S+   PD 
Sbjct: 407 KSFAGHTSNIKGALFLSDGKRIISASDDKTVRLWSLETCQEVQQLTFDTPPTSLTLSPDK 586

Query: 160 EKVLYTAGKQLIIKPLQPNAKVLQWKAHDGIILKVDWNSVNDLILSAGEDCK-YKVWDSY 218
             ++ T  + +         ++ +++A +  I     +      ++ GED K YK     
Sbjct: 587 NTIIVTHSQNIAFYQADTLREMKKFEA-EAPISSASLHQSERFFVAGGEDFKMYKFDYET 763

Query: 219 GRVLYGSQPHEHPITSVAWAPDGELFAVGSFH-TLRLCDKT-GWSYAL 264
           G+ +   + H  P+  V ++PDGEL+A GS   TLRL   T G +Y L
Sbjct: 764 GKEIESFKGHFGPVHCVRFSPDGELYASGSEDGTLRLWQTTIGRTYGL 907

 Score = 32.7 bits (73), Expect = 0.53,   Method: Compositional matrix adjust.
 Identities = 35/143 (24%), Positives = 58/143 (40%), Gaps = 3/143 (2%)
 Frame = +2

Query: 101 SVEAHCGAVLAGRWNYEGTALVTVGEDGQVKIW-SKTGMLRSTLAQQGTPVYSVAWGPDS 159
           + E H GAV     N E T   T   D   KIW ++ G    T + +   V SV +  D 
Sbjct: 158 TFEGHKGAVWGATLNREATRAATGAADFSAKIWDAEKGEELQTFSHKHI-VKSVDFSHDG 334

Query: 160 EKVLYTAGKQL--IIKPLQPNAKVLQWKAHDGIILKVDWNSVNDLILSAGEDCKYKVWDS 217
             +L  + ++L  +   +  +A+   +  H   I    + S    I+SA +D   ++W  
Sbjct: 335 TALLTGSNEKLLKVFDLVNTDAEPKSFAGHTSNIKGALFLSDGKRIISASDDKTVRLWSL 514

Query: 218 YGRVLYGSQPHEHPITSVAWAPD 240
                      + P TS+  +PD
Sbjct: 515 ETCQEVQQLTFDTPPTSLTLSPD 583
>13278
          Length = 870

 Score = 44.7 bits (104), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 31/100 (31%), Positives = 49/100 (49%), Gaps = 3/100 (3%)
 Frame = +1

Query: 197 NSVNDLIL-SAGEDCKYKVWD-SYGRVLYGSQPHEHPITSVAWAPDGELFAVGSF-HTLR 253
           N    LIL SA  D   ++W+   G  L+    H+ P+ SVA++PDG+  A GSF   + 
Sbjct: 100 NPNTSLILASASFDSTVRLWEVERGLCLHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVH 279

Query: 254 LCDKTGWSYALEKPNTGSIFNIAWSIDGTQIAGACGNGHV 293
           + +    S       TG IF + W+  G ++  +  +G V
Sbjct: 280 IWNVQTGSLVHSYKGTGGIFEVCWNHRGDKVGASASDGSV 399

 Score = 36.6 bits (83), Expect = 0.038,   Method: Compositional matrix adjust.
 Identities = 28/98 (28%), Positives = 47/98 (47%), Gaps = 2/98 (2%)
 Frame = +1

Query: 121 LVTVGEDGQVKIWS-KTGMLRSTLAQQGTPVYSVAWGPDSEKVLYTAGKQLI-IKPLQPN 178
           L +   D  V++W  + G+   TL +   PVYSVA+ PD + +   +  + + I  +Q  
Sbjct: 121 LASASFDSTVRLWEVERGLCLHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNVQTG 300

Query: 179 AKVLQWKAHDGIILKVDWNSVNDLILSAGEDCKYKVWD 216
           + V  +K   G I +V WN   D + ++  D    V D
Sbjct: 301 SLVHSYKGTGG-IFEVCWNHRGDKVGASASDGSVFVLD 411
>27681
          Length = 465

 Score = 35.8 bits (81), Expect(2) = 5e-04,   Method: Composition-based stats.
 Identities = 16/36 (44%), Positives = 19/36 (52%)
 Frame = +2

Query: 114 WNYEGTALVTVGEDGQVKIWSKTGMLRSTLAQQGTP 149
           WN EGT L T   DG  ++W   G L +TL Q   P
Sbjct: 185 WNSEGTLLATGSYDGYARLWRTDGHLVNTLGQHKGP 292

 Score = 26.2 bits (56), Expect(2) = 5e-04,   Method: Composition-based stats.
 Identities = 12/35 (34%), Positives = 17/35 (48%)
 Frame = +3

Query: 183 QWKAHDGIILKVDWNSVNDLILSAGEDCKYKVWDS 217
           +W      I  + WN   + ILSAG D    +WD+
Sbjct: 270 RWVNTRAPIFALKWNKRGNYILSAGVDKTTIIWDA 374

 Score = 32.0 bits (71), Expect = 0.86,   Method: Composition-based stats.
 Identities = 17/69 (24%), Positives = 26/69 (37%), Gaps = 15/69 (21%)
 Frame = +2

Query: 196 WNSVNDLILSAGEDCKYKVWDSYGRVLYGSQ---------------PHEHPITSVAWAPD 240
           WN  NDL+ S   D   ++W+        +                P    +TS+ W  +
Sbjct: 17  WNPTNDLLASGSGDSTARIWNMTSETPNNANQLVLRHCIQKGGTEVPSNKDVTSLDWNSE 196

Query: 241 GELFAVGSF 249
           G L A GS+
Sbjct: 197 GTLLATGSY 223
>00561
          Length = 1003

 Score = 40.0 bits (92), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 47/206 (22%), Positives = 88/206 (42%), Gaps = 17/206 (8%)
 Frame = -3

Query: 79  SFVLTSSDGKFHLISK-----------LGRVEKSVEAHCGAVLAGRWNYEGTALVTVGED 127
           S V+ SSDG + L               G+  +  E H   VL+  ++ +   +V+   D
Sbjct: 854 SDVVLSSDGNYALSGSWDQTLRLWDLAAGKTTRRFEGHTKDVLSVAFSADNRQIVSGSRD 675

Query: 128 GQVKIWSKTGMLRSTLAQQGTP--VYSVAWGPD-SEKVLYTAGKQLIIKPLQ-PNAKVL- 182
             +K+W+     + T+ + G    V  V + P+ S  ++ + G    +K     N K+  
Sbjct: 674 KTIKLWNTLAECKFTIQEDGHTDWVSCVRFSPNHSNPIIVSCGWDRTVKVWNLANCKLKN 495

Query: 183 QWKAHDGIILKVDWNSVNDLILSAGEDCKYKVWD-SYGRVLYGSQPHEHPITSVAWAPDG 241
               H+G +  V  +    L  S G+D K  +WD + G+ LY  + H   I ++ ++P+ 
Sbjct: 494 NHHGHNGYLNTVTVSPDGSLCTSGGKDSKALLWDLNDGKNLYTLE-HNDIINALCFSPNR 318

Query: 242 ELFAVGSFHTLRLCDKTGWSYALEKP 267
               V    ++++     W  A +KP
Sbjct: 317 YWLCVAYGPSIKI-----WDLACKKP 255
>19498
          Length = 903

 Score = 39.7 bits (91), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 44/203 (21%), Positives = 80/203 (39%), Gaps = 34/203 (16%)
 Frame = -1

Query: 97  RVEKSVEAHCGAVLAGRWNYEGTALVTVGEDGQVKIW-------------SKTGMLR--- 140
           RV   +++H G V   RW+  G  L + G+D  + IW             S   +L    
Sbjct: 813 RVLCQMDSHLGCVNCVRWSENGKFLASGGDDKLIMIWQISRGFGSGKSFGSNVTILEHWR 634

Query: 141 --STLAQQGTPVYSVAWGPDSEKVLYTAGKQLII--KPLQPNAKVLQWKAHDGIILKVDW 196
             +TL      V  +AW P    +   +    I+    L+ + +V   + H G++  V W
Sbjct: 633 SVATLRGHAGDVLDLAWSPQDLWLASCSVDNTIVVWNALKFSEQVAVIRGHAGMVKGVTW 454

Query: 197 NSVNDLILSAGEDCKYKVW-------DSYGRVLYGSQPHEHPITSVAWAPDGELFAVGSF 249
           + V   + S  +D   +VW       ++  +  +        +  + W+PDG    V S 
Sbjct: 453 DPVGRYLASQSDDKTLRVWRTSDWKEETCVKSCFKECGGTTHVLRLNWSPDGN--HVVSA 280

Query: 250 H-------TLRLCDKTGWSYALE 265
           H       T ++ ++ GW  +L+
Sbjct: 279 HAMNNAXPTAQIIERNGWGTSLD 211
>07781
          Length = 1269

 Score = 39.3 bits (90), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 34/85 (40%), Positives = 43/85 (50%), Gaps = 11/85 (12%)
 Frame = -2

Query: 183 QWKAHD--GIILKVD-WNSVNDLILSAGEDCKYKVWDSYGRVLYGSQP------HEHPIT 233
           QW+AHD    I   D WN+  +LI S  +DCK KVWD    +  G+ P          +T
Sbjct: 809 QWRAHDFEAWICAFDQWNT--ELIYSGSDDCKLKVWD----LRVGTTPVLTNSRFTMGVT 648

Query: 234 SVAWAPDGE-LFAVGSF-HTLRLCD 256
           S+   P  E L AVGS+   LRL D
Sbjct: 647 SIQSCPQREHLLAVGSYDENLRLFD 573
>12960
          Length = 550

 Score = 37.7 bits (86), Expect = 0.017,   Method: Compositional matrix adjust.
 Identities = 28/126 (22%), Positives = 54/126 (42%), Gaps = 2/126 (1%)
 Frame = +2

Query: 97  RVEKSVEAHCGAVLAGRWNYEGTALVTVGEDGQVKIWS-KTGMLRSTLAQQGTPVYSVAW 155
           R E ++     AV A R++ +    +T G D  VK+W+    +   T    G  V     
Sbjct: 146 RKEVTINCKQQAVRAVRFSVDSRYCMTCGSDKSVKLWNPHRELFLKTYIGHGHEVLDAQG 325

Query: 156 GPDSEKVLYTA-GKQLIIKPLQPNAKVLQWKAHDGIILKVDWNSVNDLILSAGEDCKYKV 214
             D+ ++      K +++  +     + +++ H G +  V +N  + +ILS   D   + 
Sbjct: 326 SGDNSQICSGGIDKTVVLFDVASGQALRKYRDHAGTVNCVKFNEESTVILSGSLDNTVRA 505

Query: 215 WDSYGR 220
           WD+  R
Sbjct: 506 WDTRSR 523
>19949
          Length = 903

 Score = 37.7 bits (86), Expect = 0.018,   Method: Compositional matrix adjust.
 Identities = 46/205 (22%), Positives = 75/205 (36%), Gaps = 7/205 (3%)
 Frame = +2

Query: 103 EAHCGAVLAGRWNYEGTALVTVGEDGQVKIWSKTGMLRSTLAQQGTPVYSVAWGPDSEKV 162
           + H G V   R++ +G  + +  EDG VK+W                             
Sbjct: 110 KGHTGCVCCLRFSPDGRWIASASEDGLVKLWD---------------------------- 205

Query: 163 LYTAGKQLIIKPLQPNAKVLQWKAHDGIILKVDWNSVNDLILSAGEDCKYKVWD-SYGRV 221
             TAGK L              K H   +  ++++    L+ S   D   K WD    ++
Sbjct: 206 -LTAGKLLT-----------DLKLHRDAVNTIEFHPHEFLLASGSADRTVKFWDLETFQL 349

Query: 222 LYGSQPHEHPITSVAWAPDGELFAVGSFHTLRLCDKTGWSYALEKPNTGSIFNIAW---- 277
           +  ++P  + I S+ + PDG     GS  TL++       Y  E        ++ W    
Sbjct: 350 ISTTEPEANSIRSILFHPDGVCLYSGSKDTLKV-------YHWEPLELYDTVSVPWGQVC 508

Query: 278 --SIDGTQIAGACGNGHVVFAHVVE 300
             SI  TQ+ GA      V ++VV+
Sbjct: 509 DMSISNTQLIGASFYKTNVASYVVD 583

 Score = 33.9 bits (76), Expect = 0.26,   Method: Compositional matrix adjust.
 Identities = 28/104 (26%), Positives = 50/104 (48%), Gaps = 3/104 (2%)
 Frame = +2

Query: 181 VLQWKAHDGIILKVDWNSVNDLILSAGEDCKYKVWD-SYGRVLYGSQPHEHPITSVAWAP 239
           +  +K H G +  + ++     I SA ED   K+WD + G++L   + H   + ++ + P
Sbjct: 98  IYTYKGHTGCVCCLRFSPDGRWIASASEDGLVKLWDLTAGKLLTDLKLHRDAVNTIEFHP 277

Query: 240 DGELFAVGSF-HTLRLCD-KTGWSYALEKPNTGSIFNIAWSIDG 281
              L A GS   T++  D +T    +  +P   SI +I +  DG
Sbjct: 278 HEFLLASGSADRTVKFWDLETFQLISTTEPEANSIRSILFHPDG 409
>16105
          Length = 960

 Score = 36.6 bits (83), Expect = 0.036,   Method: Compositional matrix adjust.
 Identities = 36/141 (25%), Positives = 57/141 (40%), Gaps = 7/141 (4%)
 Frame = -2

Query: 13  HQELVSCVGWTTAEE--LYSCSDDHQIVKWNLLTSETSLIVKLPDDIYPIDLHWFPKSLG 70
           HQ+    + W  + +  L S   D++I+ WN+ T E  L V +PD IY +  ++      
Sbjct: 428 HQKRCCLIVWHPSAQNVLVSAGADNKILFWNVGTGEPMLEVDVPDMIYCMSFNF------ 267

Query: 71  IKKQTQAESFVLTSSDGKFHLI-SKLGRVEKSVEAHCGAVLAGRWNYEGTALVTVG---- 125
                     V T  D K  +I S  G V K  + H GA  A     +   + T G    
Sbjct: 266 -----NGSRLVCTCKDKKLRIIDSHSGAVLKEGKCHDGAKPAQACYLKDGKVFTTGFSRM 102

Query: 126 EDGQVKIWSKTGMLRSTLAQQ 146
            + Q  IW +  +  S   ++
Sbjct: 101 SERQYAIWDENDLSESMTLEE 39

 Score = 34.3 bits (77), Expect = 0.22,   Method: Compositional matrix adjust.
 Identities = 27/114 (23%), Positives = 49/114 (42%), Gaps = 11/114 (9%)
 Frame = -2

Query: 186 AHDGIILKVDWNSVND-LILSAGEDCKYKVWD--SYGRVLYGSQP------HEHPITSVA 236
            H G +L + W   ND +I SA +DC  KVW     G V   + P      H+     + 
Sbjct: 581 GHKGAVLDIQWCPHNDNVIASASDDCTVKVWQIPDSGLVTNLTDPVVDLVGHQKRCCLIV 402

Query: 237 WAPDGE--LFAVGSFHTLRLCDKTGWSYALEKPNTGSIFNIAWSIDGTQIAGAC 288
           W P  +  L + G+ + +   +       LE      I+ ++++ +G+++   C
Sbjct: 401 WHPSAQNVLVSAGADNKILFWNVGTGEPMLEVDVPDMIYCMSFNFNGSRLVCTC 240
>03156
          Length = 1014

 Score = 36.6 bits (83), Expect = 0.037,   Method: Compositional matrix adjust.
 Identities = 27/114 (23%), Positives = 47/114 (41%), Gaps = 3/114 (2%)
 Frame = +1

Query: 134 SKTGMLRSTLAQQGTPVYSVAWGPDSEKVLYTAGKQLIIKPLQ--PNAKVLQWKAHDGII 191
           SK G L          +  V +G  S   +++A +   IK  Q   +  +  +  HD ++
Sbjct: 16  SKMGRLEDRWTGHDREITKVCYGA-SCNGMFSASRDKTIKMWQRGNSHSIRDFIGHDMVV 192

Query: 192 LKVDWNSVNDLILSAGEDCKYKVWD-SYGRVLYGSQPHEHPITSVAWAPDGELF 244
             +  N+ N L+ S   D   ++WD   G  L  +   ++ +T V W P   L 
Sbjct: 193 TAIHLNTDNTLLCSGSRDNTVRIWDVETGACLRQNNIPQNLVTDVKWLPGSHLI 354

 Score = 32.7 bits (73), Expect = 0.61,   Method: Compositional matrix adjust.
 Identities = 38/143 (26%), Positives = 66/143 (46%), Gaps = 13/143 (9%)
 Frame = +1

Query: 121 LVTVGEDGQVKIW-SKT-GMLRSTLAQQGTPVYSVAWGPDSEKVLYTA------GKQLII 172
           ++  GED +V+I+ S+T G++RS   +Q   + S     D +  L  +      G +  +
Sbjct: 352 IIQAGEDKEVRIYDSRTLGIVRSFTKKQYIQM-SCDVTADGQFCLTCSNGFGGNGCEATL 528

Query: 173 KPLQPNAKVLQWKAHDGII---LKVDWNSVNDLILSAGEDCKYKVWDSYGRVLYGSQPHE 229
             L   +   ++K H   I   L +  N    LI +A  DC  +VW+ + +     Q  E
Sbjct: 529 WQLSDGSIQNEFKGHREAIEACLFLPSNQDMTLIATASRDCSVRVWNMFTKECVCEQNFE 708

Query: 230 --HPITSVAWAPDGELFAVGSFH 250
              P+TS+    DG +  VG+F+
Sbjct: 709 GTGPLTSMIAYGDGSVL-VGTFN 774

 Score = 32.3 bits (72), Expect = 0.72,   Method: Compositional matrix adjust.
 Identities = 28/129 (21%), Positives = 56/129 (43%), Gaps = 3/129 (2%)
 Frame = +1

Query: 92  ISKLGRVEKSVEAHCGAVLAGRWNYEGTALVTVGEDGQVKIWSKTGMLRSTLAQQGTPVY 151
           +SK+GR+E     H   +    +      + +   D  +K+W + G   S     G  + 
Sbjct: 13  LSKMGRLEDRWTGHDREITKVCYGASCNGMFSASRDKTIKMWQR-GNSHSIRDFIGHDMV 189

Query: 152 SVAWGPDSEKVLYTAGKQ---LIIKPLQPNAKVLQWKAHDGIILKVDWNSVNDLILSAGE 208
             A   +++  L  +G +   + I  ++  A + Q      ++  V W   + LI+ AGE
Sbjct: 190 VTAIHLNTDNTLLCSGSRDNTVRIWDVETGACLRQNNIPQNLVTDVKWLPGSHLIIQAGE 369

Query: 209 DCKYKVWDS 217
           D + +++DS
Sbjct: 370 DKEVRIYDS 396
>01768
          Length = 1424

 Score = 36.6 bits (83), Expect = 0.044,   Method: Compositional matrix adjust.
 Identities = 33/144 (22%), Positives = 59/144 (40%), Gaps = 17/144 (11%)
 Frame = +3

Query: 140 RSTLAQQGTPVYSVAWGPDSEKVLYTAGKQLII-------KPLQPNAKVLQWKAHDGIIL 192
           +S+ A     V  V W P+   V  +      +       KP + N   +  +AH   I 
Sbjct: 816 KSSYAAHTDSVEDVQWSPNEGNVFASCSVDRTLRIWNTQQKPSKANVLTVP-EAHSRDIN 992

Query: 193 KVDWNSVND-LILSAGEDCKYKVWDSYGRVLYGSQP---------HEHPITSVAWAPDGE 242
            ++WN +   L+ S G+D   K+WD     ++ ++P         H  P+TS+ W P   
Sbjct: 993 VINWNPIEKHLLASGGDDGIIKIWD---LRMFRNKPVSAQASFKLHSQPVTSLEWNPQDS 1163

Query: 243 LFAVGSFHTLRLCDKTGWSYALEK 266
                S    ++   T W +++E+
Sbjct: 1164SVLAASGEDDQI---TIWDFSVER 1226
>21921
          Length = 1341

 Score = 36.2 bits (82), Expect = 0.058,   Method: Compositional matrix adjust.
 Identities = 25/92 (27%), Positives = 43/92 (46%), Gaps = 1/92 (1%)
 Frame = -1

Query: 158 DSEKVLYTAGKQLIIKPLQPNAKVLQWKAHDGIILKVDWNSVNDLILSAGEDCKYKVWD- 216
           D + +L    K   ++P  P  + L +K H GI+  +  +     ++S  +D   + W+ 
Sbjct: 570 DPQDLLPKLPKPKDLRPF-PTTQALVYKGHTGIVRSICPDPTGQWLVSGSDDGTIRFWEV 394

Query: 217 SYGRVLYGSQPHEHPITSVAWAPDGELFAVGS 248
           S GR +   Q     +TSVAW P+  L  V +
Sbjct: 393 SSGRCMKTLQVGGC-VTSVAWNPNPSLCVVAA 301

 Score = 30.4 bits (67), Expect = 3.1,   Method: Compositional matrix adjust.
 Identities = 21/65 (32%), Positives = 31/65 (47%), Gaps = 1/65 (1%)
 Frame = -1

Query: 103 EAHCGAVLAGRWNYEGTALVTVGEDGQVKIWS-KTGMLRSTLAQQGTPVYSVAWGPDSEK 161
           + H G V +   +  G  LV+  +DG ++ W   +G    TL Q G  V SVAW P+   
Sbjct: 492 KGHTGIVRSICPDPTGQWLVSGSDDGTIRFWEVSSGRCMKTL-QVGGCVTSVAWNPNPSL 316

Query: 162 VLYTA 166
            +  A
Sbjct: 315 CVVAA 301
>03395
          Length = 2795

 Score = 35.8 bits (81), Expect = 0.068,   Method: Compositional matrix adjust.
 Identities = 38/158 (24%), Positives = 60/158 (37%), Gaps = 13/158 (8%)
 Frame = +2

Query: 96  GRVEKSVEAHCGAVLAGRWNYEGTALVTVGEDGQVKIWSKTGMLRSTLAQQGTPVYSVAW 155
           G +  +++ H G V A + +      V+   DG   IW      RS +    T    V +
Sbjct: 116 GDLVANMKEHKGKVTAIQIHTNDRCCVSASTDGSTIIWDLITNTRSQIVLANTLFKCVCF 295

Query: 156 GPDSEKVLYTAGKQLIIKPLQPNAKVLQWKAHDGIILK------------VDWNSVNDLI 203
           G          GK L I     + K+  W+  DG +L+            +D +     I
Sbjct: 296 G----------GKDLHILTSGTDHKIGYWEVGDGGLLRELEGSQTGAINTIDIDRDGQTI 445

Query: 204 LSAGEDCKYKVWD-SYGRVLYGSQPHEHPITSVAWAPD 240
           L+ GED   K+W  + G V +    H + IT     P+
Sbjct: 446 LTGGEDSLLKLWRYNEGEVTHTGIGHSNQITKARICPN 559
>31474
          Length = 403

 Score = 34.7 bits (78), Expect = 0.16,   Method: Compositional matrix adjust.
 Identities = 20/48 (41%), Positives = 25/48 (52%), Gaps = 4/48 (8%)
 Frame = -3

Query: 114 WNYEGTALVTVGEDGQVKIWSKTG---MLRSTLAQQGT-PVYSVAWGP 157
           WN  GT L + G D  +KIW K G   + +STL    T  V S+ W P
Sbjct: 281 WNPTGTLLASCGSDKIIKIWGKEGDNWVCKSTLTDAHTRTVRSLGWSP 138

 Score = 34.3 bits (77), Expect = 0.22,   Method: Compositional matrix adjust.
 Identities = 20/68 (29%), Positives = 27/68 (39%), Gaps = 4/68 (5%)
 Frame = -3

Query: 186 AHDGIILKVDWNSVNDLILSAGEDCKYKVWDSYGRVLYG----SQPHEHPITSVAWAPDG 241
           AHD     V WN    L+ S G D   K+W   G         +  H   + S+ W+P G
Sbjct: 311 AHDEHAWCVAWNPTGTLLASCGSDKIIKIWGKEGDNWVCKSTLTDAHTRTVRSLGWSPCG 132

Query: 242 ELFAVGSF 249
              +  SF
Sbjct: 131 NYLSSASF 108
>01327
          Length = 2215

 Score = 33.9 bits (76), Expect = 0.23,   Method: Compositional matrix adjust.
 Identities = 25/113 (22%), Positives = 46/113 (40%), Gaps = 3/113 (2%)
 Frame = +3

Query: 135 KTGMLRSTLAQQGTPVYSVAWGPDSEKVLYTAGKQLIIKPLQ--PNAKVLQWKAHDGIIL 192
           + G L          +  V +G  S   +++A +   IK  Q   +  +  +  HD ++ 
Sbjct: 129 QNGRLEDRWTGHDREITKVCYGA-SCNGMFSASRDKTIKMWQRGNSHSIRDFIGHDMVVT 305

Query: 193 KVDWNSVNDLILSAGEDCKYKVWD-SYGRVLYGSQPHEHPITSVAWAPDGELF 244
            +  N+ N L+ S   D   ++WD   G  L  +   ++ +T V W P   L 
Sbjct: 306 AIHLNTDNTLLCSGSRDNTVRIWDVETGACLRQNNIPQNLVTDVKWLPGSHLI 464

 Score = 32.3 bits (72), Expect = 0.75,   Method: Compositional matrix adjust.
 Identities = 38/143 (26%), Positives = 66/143 (46%), Gaps = 13/143 (9%)
 Frame = +3

Query: 121 LVTVGEDGQVKIW-SKT-GMLRSTLAQQGTPVYSVAWGPDSEKVLYTA------GKQLII 172
           ++  GED +V+I+ S+T G++RS   +Q   + S     D +  L  +      G +  +
Sbjct: 462 IIQAGEDKEVRIYDSRTLGIVRSFTKKQYIQM-SCDVTADGQFCLTCSNGFGGNGCEATL 638

Query: 173 KPLQPNAKVLQWKAHDGII---LKVDWNSVNDLILSAGEDCKYKVWDSYGRVLYGSQPHE 229
             L   +   ++K H   I   L +  N    LI +A  DC  +VW+ + +     Q  E
Sbjct: 639 WQLSDGSIQNEFKGHREAIEACLFLPSNQDMTLIATASRDCSVRVWNMFTKECVCEQNFE 818

Query: 230 --HPITSVAWAPDGELFAVGSFH 250
              P+TS+    DG +  VG+F+
Sbjct: 819 GTGPLTSMIAYGDGSVL-VGTFN 884
>12574
          Length = 521

 Score = 33.9 bits (76), Expect = 0.23,   Method: Composition-based stats.
 Identities = 31/126 (24%), Positives = 55/126 (43%), Gaps = 12/126 (9%)
 Frame = +3

Query: 136 TGMLRSTLAQQGTPVYSVAWGPDSEKVLYTAGKQLIIKPLQPNAKVLQWKAHDGIILK-- 193
           T  L+ TLA     + +V + P+ + +  ++  +LI        K+  W A+DG   K  
Sbjct: 153 TYTLKFTLAGHTKALSAVKFSPNGDWLASSSADKLI--------KI--WGAYDGKFEKTI 302

Query: 194 ---------VDWNSVNDLILSAGEDCKYKVWD-SYGRVLYGSQPHEHPITSVAWAPDGEL 243
                    V W+S + L+ SA +D   K+W+ S G+ +   + H + +    + P   L
Sbjct: 303 AGHKLGLSDVAWSSDSKLLCSASDDKTLKIWEFSTGKCMKTLKGHSNYVFCCNFNPQSNL 482

Query: 244 FAVGSF 249
              GS 
Sbjct: 483 IVSGSL 500
>30108
          Length = 1032

 Score = 33.9 bits (76), Expect = 0.25,   Method: Compositional matrix adjust.
 Identities = 48/197 (24%), Positives = 72/197 (36%), Gaps = 20/197 (10%)
 Frame = +1

Query: 105 HCGAVLAGRWNYEGTALVTVGEDGQVKIWSKTGMLRSTLAQQ-GTPVYSVAWGPDSEKVL 163
           H   V A  W+   T      +D  V +      L   L  +    V  +AW P S  VL
Sbjct: 97  HESPVRAFAWHPHTTKFALALQDNSVHVHYSASTLVPVLKHKLQKSVAHLAWQPLSASVL 276

Query: 164 YTAGKQLII-----------KPLQPNAKVLQWKAHDGIILKVDWNSVNDLILSAGE-DCK 211
             A +  ++           +P   + +VLQ   H  I   + W    +++LSA   D  
Sbjct: 277 AVACQSAVLIWHIEPTSLAARPSSSSVQVLQHSGHCPIT-HLAWLPSANILLSASPVDTA 453

Query: 212 YKVWDSYG------RVLYGSQPHEHPITSVAWAPDGELFAVGSFHTL-RLCDKTGWSYAL 264
              W   G      R L G       ++ +A +PDG      +  TL R+ D T W   +
Sbjct: 454 VMAWSVGGEACTALRYLGGGG-----VSLLACSPDGSKVMAATPATLFRVWDTTSWHCEV 618

Query: 265 EKPNTGSIFNIAWSIDG 281
               +G   +  WS DG
Sbjct: 619 WSQLSGRCTSACWSHDG 669
>10264
          Length = 416

 Score = 32.3 bits (72), Expect = 0.66,   Method: Composition-based stats.
 Identities = 18/76 (23%), Positives = 36/76 (47%), Gaps = 3/76 (3%)
 Frame = -1

Query: 143 LAQQGTPVYSVAWGPDSEKVLYTAG--KQLIIKPLQPNAKVLQWKAHDGIILKVDWNSVN 200
           L+     V  ++W P  +  L + G   +  +  +Q    + Q+K H G +L   ++ ++
Sbjct: 257 LSGHSQRVTDMSWSPHHDARLVSVGYDAEAFVWDVQKGTALAQFKGHMGRLLTCQFSGLD 78

Query: 201 -DLILSAGEDCKYKVW 215
            DL+++ G D    VW
Sbjct: 77  PDLVMTGGSDASVHVW 30
>01598
          Length = 1545

 Score = 32.3 bits (72), Expect = 0.74,   Method: Compositional matrix adjust.
 Identities = 17/69 (24%), Positives = 34/69 (49%), Gaps = 3/69 (4%)
 Frame = +1

Query: 150  VYSVAWGPDSEKVLYTAG--KQLIIKPLQPNAKVLQWKAHDGIILKVDWNSVN-DLILSA 206
            V  ++W P  +  L + G   +  +  +Q    + Q+K H G +L   ++ ++ DL+++ 
Sbjct: 1309 VTDMSWSPHHDARLVSVGYDAEAFVWDVQKGTALAQFKGHMGRLLTCQFSGLDPDLVMTG 1488

Query: 207  GEDCKYKVW 215
            G D    VW
Sbjct: 1489 GSDASVHVW 1515
>38177
          Length = 430

 Score = 32.3 bits (72), Expect = 0.79,   Method: Composition-based stats.
 Identities = 25/103 (24%), Positives = 48/103 (46%), Gaps = 2/103 (1%)
 Frame = +3

Query: 153 VAWGPDSEKVLY--TAGKQLIIKPLQPNAKVLQWKAHDGIILKVDWNSVNDLILSAGEDC 210
           +AW P+  +++   ++G+  +   L  N + +  +AHD  +  + W++ +  +++A    
Sbjct: 6   LAWTPEGRRLVTGASSGEFTLWNGLTFNFETI-LQAHDVSVRAMRWSNHDQWMVTADHSG 182

Query: 211 KYKVWDSYGRVLYGSQPHEHPITSVAWAPDGELFAVGSFHTLR 253
             K W S    +   Q H+ PI  V  AP G   A    H +R
Sbjct: 183 YIKYWQSNMNNVKMFQGHKEPIRGVRLAPPGRTHAT---HLMR 302

 Score = 29.3 bits (64), Expect = 6.3,   Method: Composition-based stats.
 Identities = 21/83 (25%), Positives = 32/83 (38%), Gaps = 1/83 (1%)
 Frame = +3

Query: 76  QAESFVLTSSDGKFHLISKLG-RVEKSVEAHCGAVLAGRWNYEGTALVTVGEDGQVKIWS 134
           +    V  +S G+F L + L    E  ++AH  +V A RW+     +VT    G +K W 
Sbjct: 21  EGRRLVTGASSGEFTLWNGLTFNFETILQAHDVSVRAMRWSNHDQWMVTADHSGYIKYWQ 200

Query: 135 KTGMLRSTLAQQGTPVYSVAWGP 157
                         P+  V   P
Sbjct: 201 SNMNNVKMFQGHKEPIRGVRLAP 269
>31384
          Length = 474

 Score = 32.3 bits (72), Expect = 0.83,   Method: Composition-based stats.
 Identities = 16/53 (30%), Positives = 24/53 (45%)
 Frame = -1

Query: 98  VEKSVEAHCGAVLAGRWNYEGTALVTVGEDGQVKIWSKTGMLRSTLAQQGTPV 150
           + K+ + H G VL   W+ +GT + T   D   K+W         +AQ   PV
Sbjct: 159 IPKAQQTHTGPVLDVDWSDDGTKVFTASCDKTAKVWDLNSNQCMQIAQHDAPV 1

 Score = 29.3 bits (64), Expect = 6.9,   Method: Composition-based stats.
 Identities = 14/48 (29%), Positives = 21/48 (43%)
 Frame = -1

Query: 185 KAHDGIILKVDWNSVNDLILSAGEDCKYKVWDSYGRVLYGSQPHEHPI 232
           + H G +L VDW+     + +A  D   KVWD           H+ P+
Sbjct: 144 QTHTGPVLDVDWSDDGTKVFTASCDKTAKVWDLNSNQCMQIAQHDAPV 1
>02960
          Length = 1577

 Score = 32.3 bits (72), Expect = 0.85,   Method: Compositional matrix adjust.
 Identities = 50/216 (23%), Positives = 79/216 (36%), Gaps = 3/216 (1%)
 Frame = +2

Query: 13   HQELVSCVGWTTAEELYSCSDDHQIVKWNLLTSETSLIVKLPDDIYPIDLHWFPKSLGIK 72
            H E VS V W     + + S DH +  W+L T++ + +++    +  +D+ + P S    
Sbjct: 956  HAEAVSAVRWLDPHRVVTSSWDHSLRLWDLHTAQQTSLIQGSKAV--LDVAYSPLS---- 1117

Query: 73   KQTQAESFVLTSSDGKFHLISKLGRVEKSVEAHCGAVLAGRWNYEGTALVTVGEDGQVKI 132
                    +  S+D    L          V+  C                  GE  +   
Sbjct: 1118 -----HMLITGSADRHVRL----------VDPRCSE----------------GETVKCAF 1204

Query: 133  WSKTGMLRSTLAQQGTPVYSVAWGPDSEKVLYTAGKQLIIK---PLQPNAKVLQWKAHDG 189
             S TG            V  V W P  E +  +     ++K      P A +     H+ 
Sbjct: 1205 TSHTGW-----------VTGVDWSPTREHLFLSGSYDNVLKLWDTRSPKATLYDMNWHED 1351

Query: 190  IILKVDWNSVNDLILSAGEDCKYKVWDSYGRVLYGS 225
             IL VDW S+ +L+LS G D K  V+ SY     G+
Sbjct: 1352 RILAVDW-SIPELLLSGGVDNKLHVF-SYSSAKLGT 1453
>38362
          Length = 1255

 Score = 32.0 bits (71), Expect = 0.93,   Method: Compositional matrix adjust.
 Identities = 23/92 (25%), Positives = 41/92 (44%), Gaps = 18/92 (19%)
 Frame = -1

Query: 142 TLAQQGTPVYSVAWGPD---SEKVLYTAGKQLIIKPLQPNAK---------------VLQ 183
           +L     PV+ + + P+   S  +L  A K+L I  L+P  K               V  
Sbjct: 808 SLGTVTDPVHDIYFAPNVGRSYHLLAIASKELSIVSLKPLRKEPSSGSSSSKFEIRQVGL 629

Query: 184 WKAHDGIILKVDWNSVNDLILSAGEDCKYKVW 215
           + +HD  + +V WN    +++S+G D   ++W
Sbjct: 628 FDSHDSQVWRVSWNVTGTILVSSGADGCVRIW 533

 Score = 31.6 bits (70), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 19/51 (37%), Positives = 24/51 (47%), Gaps = 4/51 (7%)
 Frame = -1

Query: 103 EAHCGAVLAGRWNYEGTALVTVGEDGQVKIWSKTGM----LRSTLAQQGTP 149
           ++H   V    WN  GT LV+ G DG V+IW    +      S L   GTP
Sbjct: 625 DSHDSQVWRVSWNVTGTILVSSGADGCVRIWKANYLGSWACISVLKGDGTP 473
>03044
          Length = 1952

 Score = 30.4 bits (67), Expect = 3.1,   Method: Compositional matrix adjust.
 Identities = 21/68 (30%), Positives = 31/68 (45%), Gaps = 6/68 (8%)
 Frame = -2

Query: 187  HDGIILKVDWNSVNDLILSAGEDCKYKVWDSYGRVLYGSQPH------EHPITSVAWAPD 240
            H   +  +DW   ++ I++ G D    VW +Y    +  QPH          T V W+P+
Sbjct: 1657 HGQRVTGIDWAPKSNRIVTCGADRNAYVW-TYQDGKW--QPHLVILRINRAATCVKWSPE 1487

Query: 241  GELFAVGS 248
               FAVGS
Sbjct: 1486 ENKFAVGS 1463
>11915
          Length = 737

 Score = 30.0 bits (66), Expect = 3.4,   Method: Composition-based stats.
 Identities = 19/56 (33%), Positives = 31/56 (55%), Gaps = 2/56 (3%)
 Frame = +1

Query: 136 TGMLRS-TLAQQGTPVYSVAWGPDSEKVLYTAGKQLI-IKPLQPNAKVLQWKAHDG 189
           TG++R  +  + G   +S AW PD   + ++AG +++ + P  P  K LQ   HDG
Sbjct: 148 TGLIRRRSSVKNGCESWSCAWSPDHSYLAWSAGHRMLHLVPWNP--KTLQ--KHDG 303
>37180
          Length = 681

 Score = 30.0 bits (66), Expect = 4.1,   Method: Composition-based stats.
 Identities = 17/73 (23%), Positives = 35/73 (47%), Gaps = 2/73 (2%)
 Frame = +1

Query: 186 AHDGIILKVDWNSVNDLILSAGEDCKYKVWDSYGRVLYGS--QPHEHPITSVAWAPDGEL 243
            HD  +  V  +    L++++ +D  +++WD     L  +  Q H  P+TS  +A   ++
Sbjct: 13  GHDQELSDVHAHPTQRLVVTSSKDMTFRLWDFRDSALLVNVFQGHTQPVTSAVFASGDKV 192

Query: 244 FAVGSFHTLRLCD 256
            +     T+R+ D
Sbjct: 193 VSGSDDRTVRVWD 231
>24037
          Length = 2006

 Score = 29.3 bits (64), Expect = 5.8,   Method: Compositional matrix adjust.
 Identities = 18/64 (28%), Positives = 32/64 (50%), Gaps = 8/64 (12%)
 Frame = +2

Query: 642 EIDKVRYINAIKDLPSR--------ESKMAHILMFSGNIQEAETVLLQAGLVYQAIQINI 693
           E ++ RYIN   DL  +        + +   I  +   + EA+T L Q   +Y+A++ + 
Sbjct: 605 EKERDRYINEASDLTQKVLRHMEDIKVREMQIFDYKKKLAEADTRLRQQHNLYEAVRTDR 784

Query: 694 NLYN 697
           NLY+
Sbjct: 785 NLYS 796
>15337
          Length = 860

 Score = 28.5 bits (62), Expect = 9.8,   Method: Compositional matrix adjust.
 Identities = 12/34 (35%), Positives = 22/34 (64%)
 Frame = -1

Query: 101 SVEAHCGAVLAGRWNYEGTALVTVGEDGQVKIWS 134
           +++++ G +L   W+ +G  +VT GED  V +WS
Sbjct: 218 TMKSYFGGLLCVCWSPDGKYIVTGGEDDLVTVWS 117
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|153792526|ref|NP_080135.2| ADP-ribosylation
factor-like 1 [Mus musculus]
         (181 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

08153                                                                 210   3e-55
09827                                                                 207   2e-54
10862                                                                 128   2e-46
33605                                                                 105   1e-23
06991                                                                 104   2e-23
18208                                                                 103   3e-23
11378                                                                  97   5e-21
32860                                                                  89   8e-19
15973                                                                  65   2e-11
19506                                                                  61   2e-10
18949                                                                  57   6e-09
08428                                                                  46   7e-06
11965                                                                  40   5e-04
05468                                                                  39   0.001
33374                                                                  37   0.003
07465                                                                  37   0.005
35581                                                                  35   0.018
29196                                                                  35   0.020
25157                                                                  34   0.032
13901                                                                  33   0.059
17511                                                                  31   0.25 
27191                                                                  29   0.90 
33380                                                                  28   2.3  
01972                                                                  27   4.6  
>08153
          Length = 1703

 Score =  210 bits (534), Expect = 3e-55,   Method: Compositional matrix adjust.
 Identities = 99/165 (60%), Positives = 125/165 (75%)
 Frame = +1

Query: 16  REMRILILGLDGAGKTTILYRLQVGEVVTTIPTIGFNVETVTYKNLKFQVWDLGGQTSIR 75
           +E+RIL++GLD AGKTTILY+L++GE+VTTIPTIGFNVETV YKN+ F VWD+GGQ  IR
Sbjct: 79  KEVRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNISFTVWDVGGQDKIR 258

Query: 76  PYWRCYYSNTDAVIYVVDSCDRDRIGISKSELVAMLEEEELRKAILVVFANKQDMEQAMT 135
           P WR Y+ NT  +I+VVDS DR+RI  +K EL  ML E++LR AI++VFANKQD+  A +
Sbjct: 259 PLWRHYFQNTQGLIFVVDSNDRERINEAKEELARMLNEDDLRDAIILVFANKQDLPNAYS 438

Query: 136 PSEMANALGLPALKDRKWQIFKTSATKGTGLDEAMEWLVETLKSR 180
            SE+   LGL  LK RKW +  T AT G G+ E +EWL  TLK +
Sbjct: 439 ASEVTAHLGLANLKGRKWYMQATCATSGDGMYEGLEWLSTTLKHK 573
>09827
          Length = 1201

 Score =  207 bits (526), Expect = 2e-54,   Method: Compositional matrix adjust.
 Identities = 95/166 (57%), Positives = 125/166 (75%)
 Frame = -3

Query: 16   REMRILILGLDGAGKTTILYRLQVGEVVTTIPTIGFNVETVTYKNLKFQVWDLGGQTSIR 75
            ++MRIL++GLD AGKTTILY+L++GE+VTTIPTIGFNVETV YKN+ F VWD+GGQ  IR
Sbjct: 1118 KDMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNISFTVWDVGGQDKIR 939

Query: 76   PYWRCYYSNTDAVIYVVDSCDRDRIGISKSELVAMLEEEELRKAILVVFANKQDMEQAMT 135
            P WR Y+ NT  +I+VVDS D++R+  ++ EL  ML E+ELR A+L+VFANKQD+  AM 
Sbjct: 938  PLWRHYFQNTQGLIFVVDSNDKERVQEAREELTRMLNEDELRDAVLLVFANKQDLPHAMA 759

Query: 136  PSEMANALGLPALKDRKWQIFKTSATKGTGLDEAMEWLVETLKSRQ 181
             +E+   LGL  L++R W I  T AT G GL E ++WL   LK+ +
Sbjct: 758  TAEITEKLGLHGLRNRTWYIQSTCATTGDGLYEGLDWLSNQLKNNK 621
>10862
          Length = 2896

 Score =  128 bits (321), Expect(2) = 2e-46,   Method: Compositional matrix adjust.
 Identities = 57/121 (47%), Positives = 78/121 (64%)
 Frame = -3

Query: 59   KNLKFQVWDLGGQTSIRPYWRCYYSNTDAVIYVVDSCDRDRIGISKSELVAMLEEEELRK 118
            +  +F VWD+GGQ  IRP WR YY+ T  +I+VVD  DRDRI  ++ EL  ++ + E+R 
Sbjct: 2492 QECQFNVWDVGGQDKIRPLWRHYYTGTQGLIFVVDCADRDRIDEARQELHRIINDREMRD 2313

Query: 119  AILVVFANKQDMEQAMTPSEMANALGLPALKDRKWQIFKTSATKGTGLDEAMEWLVETLK 178
            AI+++FANKQD+  AM P E+   LGL  L+DR W +  + AT G GL E + WL    K
Sbjct: 2312 AIILIFANKQDLPDAMKPHEIQEKLGLTRLRDRNWYVQPSCATTGDGLCEGLTWLTSNHK 2133

Query: 179  S 179
            S
Sbjct: 2132 S 2130

 Score = 73.9 bits (180), Expect(2) = 2e-46,   Method: Compositional matrix adjust.
 Identities = 31/46 (67%), Positives = 43/46 (93%)
 Frame = -1

Query: 16   REMRILILGLDGAGKTTILYRLQVGEVVTTIPTIGFNVETVTYKNL 61
            +EMRIL+LGLD AGKTT+LY++++G+ VT IPT+GFNVETV++KN+
Sbjct: 2620 KEMRILMLGLDAAGKTTLLYKMKLGQSVTXIPTVGFNVETVSFKNV 2483
>33605
          Length = 888

 Score =  105 bits (261), Expect = 1e-23,   Method: Compositional matrix adjust.
 Identities = 45/91 (49%), Positives = 66/91 (72%)
 Frame = +1

Query: 16  REMRILILGLDGAGKTTILYRLQVGEVVTTIPTIGFNVETVTYKNLKFQVWDLGGQTSIR 75
           +E+R+L+LGLD AGKTTIL +    ++ T  PT+GFN++T+ ++  K  VWD+GGQ S+R
Sbjct: 493 KEVRLLMLGLDNAGKTTILKKFNGEDIDTISPTLGFNIKTLEHRGFKLNVWDVGGQQSLR 672

Query: 76  PYWRCYYSNTDAVIYVVDSCDRDRIGISKSE 106
            YWR Y+ +TD +++VVDS DR RI   K +
Sbjct: 673 SYWRNYFESTDGLVWVVDSADRMRIADCKRD 765
>06991
          Length = 1860

 Score =  104 bits (259), Expect = 2e-23,   Method: Compositional matrix adjust.
 Identities = 49/67 (73%), Positives = 60/67 (89%)
 Frame = -2

Query: 111  LEEEELRKAILVVFANKQDMEQAMTPSEMANALGLPALKDRKWQIFKTSATKGTGLDEAM 170
            LEE+EL+K+IL+VFANKQD+E AMT +E+AN+LGLP LK+RK+QIFKTSA KG GLDEAM
Sbjct: 1859 LEEDELKKSILMVFANKQDIEGAMTVTEVANSLGLPGLKNRKYQIFKTSAVKGEGLDEAM 1680

Query: 171  EWLVETL 177
            EWL  +L
Sbjct: 1679 EWLSNSL 1659
>18208
          Length = 458

 Score =  103 bits (258), Expect = 3e-23,   Method: Compositional matrix adjust.
 Identities = 46/85 (54%), Positives = 60/85 (70%)
 Frame = -1

Query: 16  REMRILILGLDGAGKTTILYRLQVGEVVTTIPTIGFNVETVTYKNLKFQVWDLGGQTSIR 75
           RE+RIL+LGLD AGKTT+L +L   +     PT GFN+++V  K  K  VWD+GGQ  IR
Sbjct: 305 RELRILLLGLDNAGKTTLLKQLASEDPSHITPTQGFNIKSVQSKGFKLNVWDIGGQRRIR 126

Query: 76  PYWRCYYSNTDAVIYVVDSCDRDRI 100
           PYW+ Y+ NTD +IYV+DS D  R+
Sbjct: 125 PYWKNYFENTDLLIYVIDSSDTKRM 51
>11378
          Length = 1688

 Score = 96.7 bits (239), Expect = 5e-21,   Method: Compositional matrix adjust.
 Identities = 49/169 (28%), Positives = 90/169 (53%), Gaps = 12/169 (7%)
 Frame = +3

Query: 19  RILILGLDGAGKTTILYRLQVGEVVTTIPTIGFNVETVTYKNLKFQVWDLGGQTSIRPYW 78
           +++ LGLD AGKTT+L+ L+  ++   +PT+    E ++   ++F  +DLGG    R  W
Sbjct: 327 KLVFLGLDNAGKTTLLHMLKDDKMAQHVPTLHPTSEELSMGGMRFTTFDLGGHRQARRVW 506

Query: 79  RCYYSNTDAVIYVVDSCDRDRIGISKSELVAMLEEEELRKAILVVFANKQDMEQAMTPSE 138
           + Y+   D ++++VD  DR+R+  +K+EL +++ +E++  A ++V  NK D   A +  E
Sbjct: 507 KDYFPAVDGIVFLVDVHDRERLVEAKAELDSLMTDEQVANAPILVLGNKIDKPGAASEEE 686

Query: 139 MANALGLPA------------LKDRKWQIFKTSATKGTGLDEAMEWLVE 175
           + +  GL +            L  R  ++F  S  K  G  E   W+ +
Sbjct: 687 IRHWFGLNSLTTGKGTVARGELPGRPMELFMCSVLKRQGYGEGFRWMAQ 833
>32860
          Length = 330

 Score = 89.4 bits (220), Expect = 8e-19,   Method: Compositional matrix adjust.
 Identities = 41/89 (46%), Positives = 58/89 (65%)
 Frame = +2

Query: 78  WRCYYSNTDAVIYVVDSCDRDRIGISKSELVAMLEEEELRKAILVVFANKQDMEQAMTPS 137
           W  YYSN++ +I V+DS DR+R+ I+K EL  ML  EELR A L+VFANKQD++  M+ +
Sbjct: 8   WNTYYSNSEFIIMVIDSTDRERLSITKEELCRMLATEELRXAALLVFANKQDIKGCMSAA 187

Query: 138 EMANALGLPALKDRKWQIFKTSATKGTGL 166
           E++  L L ++KD  W I       G G+
Sbjct: 188 EISXQLNLTSVKDHVWHIQACCGLTGEGV 274
>15973
          Length = 493

 Score = 65.1 bits (157), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 28/99 (28%), Positives = 61/99 (61%)
 Frame = -1

Query: 81  YYSNTDAVIYVVDSCDRDRIGISKSELVAMLEEEELRKAILVVFANKQDMEQAMTPSEMA 140
           Y    +A++Y+VD+ D+D++  S++EL  +L++ +L+   ++V  NK+D+  A+   E+ 
Sbjct: 487 YCRGVNAIVYMVDAADQDKLEASRNELHNLLDKPQLQGVPVLVLGNKRDLPGALDEKELI 308

Query: 141 NALGLPALKDRKWQIFKTSATKGTGLDEAMEWLVETLKS 179
           + + L A++DR+   +  S  +   +D  ++WL++  KS
Sbjct: 307 DRMNLSAIQDREICCYSISCKEKENIDITLQWLIQHSKS 191
>19506
          Length = 421

 Score = 61.2 bits (147), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 27/41 (65%), Positives = 35/41 (85%)
 Frame = -3

Query: 16  REMRILILGLDGAGKTTILYRLQVGEVVTTIPTIGFNVETV 56
           + + ++  GLD AGKTT+LY L++GEVVTTIPTIGFNVET+
Sbjct: 140 KPVTVIYFGLDAAGKTTLLYNLKLGEVVTTIPTIGFNVETL 18
>18949
          Length = 414

 Score = 56.6 bits (135), Expect = 6e-09,   Method: Compositional matrix adjust.
 Identities = 26/86 (30%), Positives = 48/86 (55%)
 Frame = +3

Query: 44  TTIPTIGFNVETVTYKNLKFQVWDLGGQTSIRPYWRCYYSNTDAVIYVVDSCDRDRIGIS 103
           T +PT     E ++   + F  +DLGG    R  W+ Y+   D ++++VD  D +RI  +
Sbjct: 18  TGLPT----SEELSMGGMTFTTFDLGGHRQARRVWKDYFPAVDGIVFIVDVHDTERITEA 185

Query: 104 KSELVAMLEEEELRKAILVVFANKQD 129
           K+EL ++L ++++    ++V  NK D
Sbjct: 186 KAELDSLLRDDQIADIPVLVLGNKMD 263
>08428
          Length = 1109

 Score = 46.2 bits (108), Expect = 7e-06,   Method: Compositional matrix adjust.
 Identities = 34/122 (27%), Positives = 53/122 (43%), Gaps = 5/122 (4%)
 Frame = -3

Query: 16   REMRILILGLDGAGKTTILYRLQVGEVVTTI-PTIGFNVET----VTYKNLKFQVWDLGG 70
            R++++ +LG  G GK++I+ R   G    +   TIG +  +    V     +FQ+WD  G
Sbjct: 1074 RDVKVCLLGDSGVGKSSIVLRFVTGSYRPSQESTIGASFMSKSLVVDGAGYRFQIWDTAG 895

Query: 71   QTSIRPYWRCYYSNTDAVIYVVDSCDRDRIGISKSELVAMLEEEELRKAILVVFANKQDM 130
            Q   R     YY    A + V D   R R   S    +  L        +L +  NK D+
Sbjct: 894  QEKFRALAPMYYRGAAAAVIVYD-VTRPRTFKSVKSWIQELRSFGPPNIVLAIAGNKCDL 718

Query: 131  EQ 132
            E+
Sbjct: 717  EE 712
>11965
          Length = 3256

 Score = 40.0 bits (92), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 26/97 (26%), Positives = 47/97 (48%), Gaps = 10/97 (10%)
 Frame = +1

Query: 44  TTIPTIGFNVETVTYKNLKFQVWDLGGQTSIRPYWRCYYSNTDAVIYVVDSCDRDRIGIS 103
           T + T G      ++KNL F+++D+GGQ S R  W   + +  A+I+ V   + D++   
Sbjct: 133 TRVKTTGIVEVHFSFKNLNFKLFDVGGQRSERKKWIHCFEDVTAIIFCVAMSEYDQVLHE 312

Query: 104 KSELVAMLEEEELRKAI----------LVVFANKQDM 130
                 M E  +L  +I          +++F NK+D+
Sbjct: 313 DETTNRMQESLKLFDSICNNKWFTDTSIILFLNKKDL 423
>05468
          Length = 1558

 Score = 39.3 bits (90), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 42/172 (24%), Positives = 75/172 (43%), Gaps = 16/172 (9%)
 Frame = -3

Query: 19   RILILGLDGAGKTTIL-----------YRLQVGEVVTTIPTIGFNVETVTYKNLKFQVWD 67
            +IL++G  G GKT+I+           YR  +G V   +  + ++ +T+    ++ Q+WD
Sbjct: 1535 KILVIGELGTGKTSIIKRYVHQFFSQHYRATIG-VDFALKVLNWDADTL----IRLQLWD 1371

Query: 68   LGGQTSIRPYWRCYYSNTDAVIYVVD---SCDRDRIGISKSELVAMLEEEELRKAILVVF 124
            + GQ       R YY        V D   +   D +   K++L + ++  +      V+ 
Sbjct: 1370 IAGQERFGNMTRVYYKEAVGAFVVFDVTRASTFDAVTKWKNDLDSKVQLADGSPVPCVLL 1191

Query: 125  ANKQDMEQAMTPSEMANALGLPALKDRKWQI--FKTSATKGTGLDEAMEWLV 174
            ANK D  +      + N   +      K  I  ++TSA +   +DEA  +LV
Sbjct: 1190 ANKCDQAK---EGLVNNTSQMDEFCSEKGFIGWYETSAKENINIDEAARFLV 1044
>33374
          Length = 489

 Score = 37.4 bits (85), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 20/70 (28%), Positives = 33/70 (47%)
 Frame = +1

Query: 61  LKFQVWDLGGQTSIRPYWRCYYSNTDAVIYVVDSCDRDRIGISKSELVAMLEEEELRKAI 120
           +KF++WD  GQ         YY    A I V D  ++D  G +K+  V  L+ +     +
Sbjct: 175 VKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNQDTFGRAKT-WVKELQRQASPNIV 351

Query: 121 LVVFANKQDM 130
           + +  NK D+
Sbjct: 352 IALAGNKADL 381
>07465
          Length = 1103

 Score = 36.6 bits (83), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 27/118 (22%), Positives = 51/118 (43%), Gaps = 1/118 (0%)
 Frame = +3

Query: 59  KNLKFQVWDLGGQTSIRPYWRCYYSNTDAVIYVVDSCDRDRIGISKSELVAMLEEEELRK 118
           ++++  +WD  GQ       + YY    A +    + DRD       E      E+E+ +
Sbjct: 339 EDVRLMLWDTAGQEEFDAITKAYYRGAQACVLAFSTVDRD--SFEALETWKRKVEDEVGE 512

Query: 119 AILVVFANKQDM-EQAMTPSEMANALGLPALKDRKWQIFKTSATKGTGLDEAMEWLVE 175
             +V+  NK D+ + A+   E A  L     K  + + ++TS  +   +DE   +L +
Sbjct: 513 IGMVIVQNKIDLIDDAVVRPEEAENLA----KKLRLRFYRTSVKENMNVDEVFRYLAD 674
>35581
          Length = 364

 Score = 35.0 bits (79), Expect = 0.018,   Method: Compositional matrix adjust.
 Identities = 26/84 (30%), Positives = 40/84 (47%), Gaps = 7/84 (8%)
 Frame = +2

Query: 18  MRILILGLDGAGKTTILYRLQVGEVV----TTIPTIGFNVETVTYKN---LKFQVWDLGG 70
            + ++LG  G GKT +L RL   + +    T++ T    + TVT  +       +WD  G
Sbjct: 47  FKCVLLGDAGVGKTCLLNRLATDKFLDSPLTSLTTASL-LTTVTLTSGVMASVDLWDTAG 223

Query: 71  QTSIRPYWRCYYSNTDAVIYVVDS 94
           Q   R     YY +T AV+ V D+
Sbjct: 224 QERYRSLTSSYYRDTKAVLIVYDA 295
>29196
          Length = 431

 Score = 34.7 bits (78), Expect = 0.020,   Method: Compositional matrix adjust.
 Identities = 15/42 (35%), Positives = 26/42 (61%)
 Frame = -2

Query: 59  KNLKFQVWDLGGQTSIRPYWRCYYSNTDAVIYVVDSCDRDRI 100
           KNL F+++D+GGQ S R  W   + +  A+I+ V   + D++
Sbjct: 229 KNLNFKLFDVGGQRSERKKWIHCFEDVTAIIFCVAMSEYDQV 104
>25157
          Length = 627

 Score = 34.3 bits (77), Expect = 0.032,   Method: Compositional matrix adjust.
 Identities = 23/88 (26%), Positives = 47/88 (53%), Gaps = 10/88 (11%)
 Frame = +3

Query: 19  RILILGLDGAGKTTI----LYRLQVGEVV---TTIPTIGFNVETVTYKNLKFQVWDLGGQ 71
           RIL++GL  +GK++I     +++   E +   +T   +  ++   ++  ++FQVWD+ GQ
Sbjct: 48  RILLMGLRRSGKSSIQKVVFHKVSPNETLFLESTNKIVKDDISNSSF--VRFQVWDIPGQ 221

Query: 72  TS-IRPYWRC--YYSNTDAVIYVVDSCD 96
                P +     +    A+I+V+D+ D
Sbjct: 222 IDFFDPTFDSDMIFGGCGALIFVIDAQD 305
>13901
          Length = 962

 Score = 33.1 bits (74), Expect = 0.059,   Method: Compositional matrix adjust.
 Identities = 21/90 (23%), Positives = 40/90 (44%), Gaps = 14/90 (15%)
 Frame = -3

Query: 18  MRILILGLDGAGKTTIL-----------YRLQVGEVVTTIPTIGFNVETVTYK---NLKF 63
            +++I+G    GKT+ +           Y++ +G        + F ++ + +    N+K 
Sbjct: 285 FKVIIIGDPTVGKTSFVQRYVNDSFRRDYKMTIG--------VDFALKVIRWSDKCNIKL 130

Query: 64  QVWDLGGQTSIRPYWRCYYSNTDAVIYVVD 93
           Q+WD+ GQ       R YY +  A I + D
Sbjct: 129 QLWDIAGQERFTSMTRVYYKDAHACIVMFD 40
>17511
          Length = 483

 Score = 31.2 bits (69), Expect = 0.25,   Method: Compositional matrix adjust.
 Identities = 21/81 (25%), Positives = 37/81 (45%), Gaps = 5/81 (6%)
 Frame = -3

Query: 18  MRILILGLDGAGKTTILYRLQVGEVVTTI-PTIGFNVET----VTYKNLKFQVWDLGGQT 72
           ++++ILG  G GKT+++ +    +       TIG +  T    V  + +  Q+WD  GQ 
Sbjct: 364 LKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQIWDTAGQE 185

Query: 73  SIRPYWRCYYSNTDAVIYVVD 93
             +     +Y   D  + V D
Sbjct: 184 RFQSLGVAFYRGADCCVLVFD 122
>27191
          Length = 443

 Score = 29.3 bits (64), Expect = 0.90,   Method: Compositional matrix adjust.
 Identities = 15/51 (29%), Positives = 25/51 (49%), Gaps = 4/51 (7%)
 Frame = +1

Query: 47  PTIG----FNVETVTYKNLKFQVWDLGGQTSIRPYWRCYYSNTDAVIYVVD 93
           PT+G    F ++TV   +++  +WDL G           Y+ +DA+  V D
Sbjct: 55  PTVGVDYGFKIQTVNGVDMRVHMWDLSGSNEYLDVRNELYTGSDAIFIVFD 207
>33380
          Length = 282

 Score = 28.1 bits (61), Expect = 2.3,   Method: Compositional matrix adjust.
 Identities = 18/73 (24%), Positives = 30/73 (41%)
 Frame = +3

Query: 59  KNLKFQVWDLGGQTSIRPYWRCYYSNTDAVIYVVDSCDRDRIGISKSELVAMLEEEELRK 118
           K +K Q+WD  GQ   R     YY      I + D  + +    +  +    ++      
Sbjct: 54  KRVKLQIWDTAGQERYRTITTAYYRGAMGFILMYDVTNEESFN-AVQDWCTQIKTYSWDN 230

Query: 119 AILVVFANKQDME 131
           A +V+  NK D+E
Sbjct: 231 AQVVLVGNKCDLE 269
>01972
          Length = 2359

 Score = 26.9 bits (58), Expect = 4.6,   Method: Compositional matrix adjust.
 Identities = 29/139 (20%), Positives = 48/139 (34%), Gaps = 7/139 (5%)
 Frame = +3

Query: 46  IPTIGFNVETVTYK----NLKFQVWDLGGQTSIRPYWRCYYSNTDAVIYVVDSCDR---D 98
           + T+G  V  + +      LKF VWD  GQ         YY      + + D   R    
Sbjct: 390 VATLGVEVHPLLFHTSRGKLKFNVWDTAGQEKFGGLRDGYYIQGQCAVIMFDVTSRVTYK 569

Query: 99  RIGISKSELVAMLEEEELRKAILVVFANKQDMEQAMTPSEMANALGLPALKDRKWQIFKT 158
            +     +LV + E        +V+  NK D++          A  +   + +  Q +  
Sbjct: 570 NVPNWHRDLVRVCEN-----IPIVLCGNKVDIK-----DRKVKAKAIVFHRKKNLQYYDI 719

Query: 159 SATKGTGLDEAMEWLVETL 177
           SA      ++   WL   L
Sbjct: 720 SAKSNYNFEKPFLWLARKL 776
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|124248487|ref|NP_084530.3| tumor suppressor candidate
3 [Mus musculus]
         (347 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

20880                                                                 211   5e-55
04156                                                                  31   0.89 
26548                                                                  28   5.2  
>20880
          Length = 576

 Score =  211 bits (536), Expect = 5e-55,   Method: Compositional matrix adjust.
 Identities = 94/171 (54%), Positives = 122/171 (71%)
 Frame = -1

Query: 177 QLAKWIADRTDVHIRVFRPPNYSGTIXXXXXXXXXXXXXXXRRNNLEFIYNKTGWAMVSL 236
           Q+AKW+A+RTDV IRVFRPPNYSGT+               +RNNLEF+YNK  WAM++L
Sbjct: 576 QIAKWVAERTDVQIRVFRPPNYSGTLALVLLFALVGGLLYLKRNNLEFLYNKNCWAMLAL 397

Query: 237 CIVFAMTSGQMWNHIRGPPYAHKNPHNGQVSYIHGSSQAQFVAESHIILVLNAAITMGMV 296
            ++FAMTSGQMWNHIRGPP  H+NP+ GQ+ YIHGSSQ QF+ E++I+++L+ ++ +G +
Sbjct: 396 AVIFAMTSGQMWNHIRGPPLMHRNPNTGQMHYIHGSSQGQFIMETYIVMLLHCSVVVGFI 217

Query: 297 LLNEAATSKGDVGKRRIICXXXXXXXXXXXXXXXXIFRSKYHGYPYSFLIK 347
           +LNEA+T KGD GKRRI+                 +FRSKY GYPYSFL K
Sbjct: 216 MLNEASTLKGDPGKRRILALAGLGCVAIFFSLLLSVFRSKYQGYPYSFLFK 64
>04156
          Length = 1401

 Score = 30.8 bits (68), Expect = 0.89,   Method: Compositional matrix adjust.
 Identities = 10/22 (45%), Positives = 16/22 (72%)
 Frame = +2

Query: 251 IRGPPYAHKNPHNGQVSYIHGS 272
           + GPPYA ++ HNG+++  H S
Sbjct: 515 VEGPPYAGRDRHNGEIAAFHLS 580
>26548
          Length = 1000

 Score = 28.1 bits (61), Expect = 5.2,   Method: Compositional matrix adjust.
 Identities = 16/41 (39%), Positives = 19/41 (46%)
 Frame = +2

Query: 275 AQFVAESHIILVLNAAITMGMVLLNEAATSKGDVGKRRIIC 315
           A F    ++ L LN   T G +LLN  ATSK     R   C
Sbjct: 242 APFNRXRYLPLALNVFXTSGYILLNSTATSKAKSKCRSQCC 364
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|159110415|ref|NP_032218.2| guanylate cyclase 2e [Mus
musculus]
         (1108 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

34057                                                                 150   5e-55
29215                                                                  95   2e-19
07291                                                                  62   1e-09
01718                                                                  62   1e-09
06405                                                                  61   2e-09
09572                                                                  60   5e-09
00715                                                                  55   1e-07
20640                                                                  55   2e-07
09007                                                                  54   3e-07
04852                                                                  51   3e-06
19301                                                                  48   3e-05
08294                                                                  47   3e-05
29581                                                                  46   6e-05
11780                                                                  42   1e-04
18921                                                                  45   1e-04
01756                                                                  44   3e-04
07940                                                                  44   3e-04
18996                                                                  44   3e-04
04591                                                                  44   4e-04
14116                                                                  43   6e-04
17637                                                                  41   0.003
09606                                                                  40   0.005
07836                                                                  39   0.008
19094                                                                  35   0.13 
27546                                                                  35   0.14 
30464                                                                  34   0.25 
04138                                                                  33   0.91 
00392                                                                  32   1.3  
37602                                                                  32   1.9  
11185                                                                  30   4.2  
11995                                                                  30   5.1  
31768                                                                  30   5.2  
13066                                                                  30   6.9  
19708                                                                  30   7.0  
>34057
          Length = 724

 Score =  150 bits (378), Expect(2) = 5e-55,   Method: Compositional matrix adjust.
 Identities = 70/128 (54%), Positives = 93/128 (72%)
 Frame = +3

Query: 841 RTEELEQEKQKTDRLLTQMLPPSVAEALKMGTSVEPEYFEEVTLYFSDIVGFTTISAMSE 900
           + E  +QEK++TD LL QMLP SVA+ LK    V  E + E T++FSDI GFT ISA S 
Sbjct: 102 QNEGAKQEKKRTDTLLYQMLPKSVADQLKRNEVVTAETYSESTIFFSDIQGFTQISARSS 281

Query: 901 PIEVVDLLNDLYTLFDAIIGAHDVYKVETIGDAYMVASGLPQRNGQRHAAEIANMSLDIL 960
           P++VV++LN LY  FD  +  +DVYKVETIGDAYMV SG+P++NG+RHAAEI  M+LD+L
Sbjct: 282 PVQVVEMLNSLYLCFDERLALYDVYKVETIGDAYMVVSGVPKKNGKRHAAEIGTMTLDLL 461

Query: 961 SAVGSFRM 968
            ++    +
Sbjct: 462 DSISRLEI 485

 Score = 84.3 bits (207), Expect(2) = 5e-55,   Method: Compositional matrix adjust.
 Identities = 42/74 (56%), Positives = 53/74 (71%)
 Frame = +2

Query: 970  HMPEVPVRIRIGLHSGPCVAGVVGLTMPRYCLFGDTVNTASRMESTGLPYRIHVNMSTVR 1029
            H+P    ++RIG HSGP VAGVVG  MPRYCLFG+TV+ A++MES G P RIH++ +T  
Sbjct: 488  HLPGTKFKLRIGCHSGPVVAGVVGSKMPRYCLFGETVSVAAKMESLGKPGRIHISQTTHD 667

Query: 1030 ILRALDQGFQMECR 1043
             L +L  GF ME R
Sbjct: 668  ALLSLG-GFVMEQR 706
>29215
          Length = 698

 Score = 94.7 bits (234), Expect = 2e-19,   Method: Composition-based stats.
 Identities = 46/84 (54%), Positives = 57/84 (67%)
 Frame = -1

Query: 991  VVGLTMPRYCLFGDTVNTASRMESTGLPYRIHVNMSTVRILRALDQGFQMECRGRTELKG 1050
            VVG  MPRYCLFGDTVNTASRMESTG   +I V+  T   L ++   + +E RG  E+KG
Sbjct: 698  VVGSKMPRYCLFGDTVNTASRMESTGEADKIQVSRGTYHALLSMTSEYTLEPRGAVEIKG 519

Query: 1051 KGIEDTYWLVGRLGFNKPIPKPPD 1074
            KG  DTYWL+ + GF K +P  P+
Sbjct: 518  KGPMDTYWLMDKEGFEKSLPCMPN 447
>07291
          Length = 833

 Score = 62.4 bits (150), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 47/164 (28%), Positives = 78/164 (47%), Gaps = 5/164 (3%)
 Frame = +1

Query: 653 LIKGMRYLHHRGVAHGRLKSRNCVV--DGRFVLKVTDHG-HGRLLEAQRVLPEPPSAEDQ 709
           +  GM YL    V H  L +RNC+V  DGR  L+++D+G  G L        +   A D 
Sbjct: 76  IADGMAYLQEVKVVHRNLAARNCIVTEDGR--LQLSDYGVTGSLFPQSYYTADDSPARDL 249

Query: 710 L-WTAPELLRDPSLERRGTLAGDVFSLAIIMQEVVCRS-TPYAMLELTPEEVIQRVRSPP 767
           + W APE + +     +     DV++  +++ E++ R  TPY  +E +   ++  ++   
Sbjct: 250 VKWMAPETIDNFHFSSK----SDVWAFGVVLWELLTRGITPYPDVENS--SLLPYLKEGH 411

Query: 768 PLCRPLVSMDQAPMECIQLMTQCWAEHPELRPSMDLTFDLFKSI 811
            + +P     Q+P    ++MT CW E PE RP      D  K+ 
Sbjct: 412 RMKKP----KQSPEPVYEMMTACWNESPEQRPDFAELNDQLKTF 531
>01718
          Length = 959

 Score = 62.4 bits (150), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 60/245 (24%), Positives = 103/245 (42%), Gaps = 11/245 (4%)
 Frame = +3

Query: 587 LRELRHENVALYLGLFLAGTADSPATPGEGILAVVSEHCARGSLHDLLAQREIKLDWMFK 646
           L  L+H N+  ++G+ +           EG L  ++E+   G+L  LL +++ +L W  +
Sbjct: 294 LNRLQHANILRFMGVCVH----------EGQLHALTEYIPSGNLEQLLEKKDEELPWTQR 443

Query: 647 SSLLLDLIKGMRYLHHRGVAHGRLKSRNCVVDGRFVLKVTDHGHGRLLEA---QRVLPEP 703
             L L L +G+ YLH     H  L S+N ++      +  +HG+  ++        +P+P
Sbjct: 444 IQLTLGLARGLDYLHSTRFIHRDLTSKNILIR-----REDNHGYHAVIADFGLATKIPDP 608

Query: 704 ------PSAEDQLWTAPELLRDPSLERRGTLAGDVFSLAIIMQEVVCR--STPYAMLELT 755
                 P+     W APE+L       R     D+FS+ IIM E+  R  + P  M  + 
Sbjct: 609 LDKEKLPTVGSPYWMAPEVLNGHFYNER----ADLFSVGIIMCEITARIPADPDIMPRMN 776

Query: 756 PEEVIQRVRSPPPLCRPLVSMDQAPMECIQLMTQCWAEHPELRPSMDLTFDLFKSINKGR 815
              V     S          +   P++ +QL  +C    P+ RP      +  + I K  
Sbjct: 777 NFGVDYVALSE--------MISYCPLDYLQLAFKCCQVDPQKRPRGVEIIEWLEKIFKNL 932

Query: 816 KTNII 820
           K +I 
Sbjct: 933 KNDIF 947
>06405
          Length = 1965

 Score = 61.2 bits (147), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 64/247 (25%), Positives = 111/247 (44%), Gaps = 4/247 (1%)
 Frame = +1

Query: 587 LRELRHENVALYLGLFLAGTADSPATPGEGILAVVSEHCARGSLHDLLAQREIKLDWMFK 646
           ++E++H N+   LG+    T + P         +V+E    G+L D L  R    +    
Sbjct: 409 MKEMKHPNLVQLLGVC---TREPP-------FYIVTEFMPHGNLLDYL--RSSTREENGP 552

Query: 647 SSLLL---DLIKGMRYLHHRGVAHGRLKSRNCVVDGRFVLKVTDHGHGRLLEAQRVLPEP 703
           ++L+     +  GM YL  +   H  L +RNC+V    ++KV D G  RL++        
Sbjct: 553 TALMYMATQIASGMAYLETKNFIHRDLAARNCLVADSNMVKVADFGLARLMKDDTYTAHI 732

Query: 704 PSAEDQLWTAPELLRDPSLERRGTLAGDVFSLAIIMQEVVCRS-TPYAMLELTPEEVIQR 762
            +     WTAPE L   +  R  T + D+++  +++ E+     +PY  +ELT  EV   
Sbjct: 733 GAKFPIKWTAPEGL---AFNRFSTRS-DIWAFGVLLWELATYGMSPYPGVELT--EVYHL 894

Query: 763 VRSPPPLCRPLVSMDQAPMECIQLMTQCWAEHPELRPSMDLTFDLFKSINKGRKTNIIDS 822
           +     + RP       P +   LM +CW   P+ RP+      L +  N   K++I + 
Sbjct: 895 LERGYRMERP----PGTPADVYILMLKCWQWDPKDRPTFKEIHFLLE--NMFEKSSICEE 1056

Query: 823 MLRMLEQ 829
           + + LE+
Sbjct: 1057VEKELEK 1077
>09572
          Length = 1081

 Score = 60.1 bits (144), Expect = 5e-09,   Method: Composition-based stats.
 Identities = 35/72 (48%), Positives = 44/72 (61%)
 Frame = -1

Query: 991  VVGLTMPRYCLFGDTVNTASRMESTGLPYRIHVNMSTVRILRALDQGFQMECRGRTELKG 1050
            V+G T   Y ++GDTVN ASRM STG P RI V  ST   L  L++ F+ E RG   +KG
Sbjct: 1081 VIGTTKLLYDIWGDTVNIASRMYSTGEPDRIQVPQST---LPKLEEMFEFEYRGEIMVKG 911

Query: 1051 KGIEDTYWLVGR 1062
            KG   TY + G+
Sbjct: 910  KGNMKTYLVKGK 875
>00715
          Length = 1788

 Score = 55.5 bits (132), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 69/254 (27%), Positives = 105/254 (41%), Gaps = 32/254 (12%)
 Frame = +1

Query: 590 LRHENVALYLGLFLAGTADSPATPGEGILAVVSEHCARGSLHDLLAQREIKLDWMFKSSL 649
           LRH NV   LG      A S     +G   +  E+    +L  +L   +  +D   + SL
Sbjct: 97  LRHVNVVSILG------ATSLHRFEDGAW-LAMEYVGPLNLQTILNDHQQDIDSSMRLSL 255

Query: 650 LLDLIKGMRYLHHRGVAHGRLKSRNCVVDGRFVLKVTDHGHGRLL--------------- 694
            L + +G+ YLH   + H  LK  NC++     L++ D G    L               
Sbjct: 256 ALQMARGLHYLHSINIVHLDLKPANCLLTRDLKLRIADFGCCHQLTPTGLDMGEREGGMA 435

Query: 695 -EAQRVLPEPPSAEDQL-----WTAPELLR--DPSLERRGTLAGDVFSLAIIMQEVVCRS 746
                + P   + +++L     + APELL+   PS+        DV+SL I + ++  R 
Sbjct: 436 GNELELTPVQGAWKNELAGTLAYRAPELLKGLQPSVR------SDVYSLGITLWQMCTRQ 597

Query: 747 TPYAMLELTP-EEVIQRVRS------PPPLCRPLVSMDQAPMECI--QLMTQCWAEHPEL 797
            PY   E  P   V+ +V S      PPP      S +  P E +   L TQCWA   E 
Sbjct: 598 GPY---EGVPAHAVVYQVVSKDLRPCPPP------STEDDPFEVMFRDLYTQCWARRVED 750

Query: 798 RPSMDLTFDLFKSI 811
           RP+   + D+  +I
Sbjct: 751 RPT---SLDVVHAI 783
>20640
          Length = 1492

 Score = 54.7 bits (130), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 44/160 (27%), Positives = 72/160 (45%), Gaps = 4/160 (2%)
 Frame = +1

Query: 663 RGVAHGRLKSRNCVVDGRFVLKVTDHGHGRLLEAQRVLPEPPSAEDQL---WTAPELLRD 719
           RG  H  L +RNC+V    V+K++D G  R + +  V     S  D +   W   E +  
Sbjct: 1   RGYVHRDLATRNCLVGHDLVVKISDFGLARSVHS--VDYYRGSEHDAIPIRWMPLEAI-- 168

Query: 720 PSLERRGTLAGDVFSLAIIMQEVVCRS-TPYAMLELTPEEVIQRVRSPPPLCRPLVSMDQ 778
             L  + +   DV+S  +++ E+   +  PY    LT EEV++ V+    L  P    ++
Sbjct: 169 --LYNKFSTQSDVWSFGVVLWEIFAFALQPY--YGLTHEEVVRFVKEGKVLACP----ER 324

Query: 779 APMECIQLMTQCWAEHPELRPSMDLTFDLFKSINKGRKTN 818
            P    +LM QCW   P  RPS        ++++   + N
Sbjct: 325 TPPPMYELMKQCWHRRPATRPSFHTLHKTLENMHSKYEKN 444
>09007
          Length = 1440

 Score = 54.3 bits (129), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 54/228 (23%), Positives = 99/228 (43%), Gaps = 9/228 (3%)
 Frame = -1

Query: 587 LRELRHENVALYLGLFLAGTADSPATPGEGILAVVSEHCARGSLHDLLAQREIKLDWMFK 646
           ++ L HEN+    G+ +   AD         + +V+E     SL + + +   ++D  F 
Sbjct: 714 MQMLDHENIVRVYGVVMDNGAD---------IMLVTELAPMRSLLECVKEVSARVD--FS 568

Query: 647 SSLLLDLIK----GMRYLHHRGVAHGRLKSRNCVVDGRFVLKVTDHG-HGRLLEAQRVLP 701
              L D  +    GM YL  + + H  L +RN ++  +  +K++D G  G L   +    
Sbjct: 567 VPRLCDFSQQVCDGMSYLESKRLVHRDLAARNILLFSKSKVKISDVGVSGALGAGKEYYQ 388

Query: 702 EPPSAEDQ---LWTAPELLRDPSLERRGTLAGDVFSLAIIMQEVVCRS-TPYAMLELTPE 757
              +   Q    W APE  R+       + A DV++  +++ E       P+A   L  +
Sbjct: 387 SQQTIHLQNAVAWCAPESFRNLCF----SSASDVWAFGVLLWEFFTHGFQPWA--GLNGQ 226

Query: 758 EVIQRVRSPPPLCRPLVSMDQAPMECIQLMTQCWAEHPELRPSMDLTF 805
           ++++ V +P    + L   D  P E   +M +CW + P+ RP+    F
Sbjct: 225 QIMEAVDAPQS--QRLEQPDLCPKEYYAVMLKCWEQEPQRRPTFSQLF 88
>04852
          Length = 1462

 Score = 51.2 bits (121), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 60/240 (25%), Positives = 85/240 (35%), Gaps = 30/240 (12%)
 Frame = +1

Query: 592 HENVALYLGLFLAGTADSPATPGEGILAVVSEHCARGSLHDLLAQREIKLD--------- 642
           H N+  +LG    G          G L V+ E    G+L D L      ++         
Sbjct: 127 HINIVNFLGCCTQG----------GPLWVIVEFAKNGNLRDFLESCRDGINGYGKFVSPQ 276

Query: 643 ---WMFKS------------SLLLDLIKGMRYLHHRGVAHGRLKSRNCVVDGRFVLKVTD 687
              W  K+            S    + +GM +L  R   H  L +RN +V    VLK+ D
Sbjct: 277 DPGWYTKTPGGHVIRRKNLLSYAFQIARGMEFLASRKCIHRDLAARNVLVTEEHVLKIAD 456

Query: 688 HGHGRL--LEAQRVLPEPPSAEDQLWTAPELLRDPSLERRGTLAGDVFSLAIIMQEVVCR 745
            G  R      +R     P      W APE L D     R T   DV+S  +++ E+   
Sbjct: 457 FGLSRTGDYYKKRSGGRLPVK----WMAPEALFD----MRYTTKSDVWSFGVVLWEIFSL 612

Query: 746 -STPYAML---ELTPEEVIQRVRSPPPLCRPLVSMDQAPMECIQLMTQCWAEHPELRPSM 801
              PYA +   EL  + +    R P P        + A      +M +CW   P  RP  
Sbjct: 613 GGMPYASIPNEELYSKLLDDAYRMPRP--------ELASGNLYAIMERCWLNRPSDRPEF 768
>19301
          Length = 712

 Score = 47.8 bits (112), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 34/119 (28%), Positives = 55/119 (46%), Gaps = 5/119 (4%)
 Frame = +2

Query: 576 IRPATKTAFSKLRELRHENVALYLGLFLAGTADSPATPGEGILAVVSEHCARGSLHDLLA 635
           +R   +T    LR+L H N+  + G+       +P         ++ E+C  G L+++L 
Sbjct: 398 VRDIKETDIRNLRKLNHPNIISFKGV----CTQAPC------YCIIMEYCPYGQLYEVLR 547

Query: 636 Q-REIK----LDWMFKSSLLLDLIKGMRYLHHRGVAHGRLKSRNCVVDGRFVLKVTDHG 689
             +EI     LDW  +      +  GM YLH   + H  LKS N +V    V+K++D G
Sbjct: 548 DGKEIPPALVLDWSKQ------IASGMNYLHSHKIIHRDLKSPNVLVAKNDVVKISDFG 706
>08294
          Length = 1849

 Score = 47.4 bits (111), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 49/192 (25%), Positives = 81/192 (42%), Gaps = 12/192 (6%)
 Frame = +2

Query: 620  VVSEHCARGSLHD-LLAQREIK----------LDWMFKSSLLLDLIKGMRYLHHRGVAHG 668
            +++E+C  G L   LLA R             L    K  +   +  GM  L ++G+ HG
Sbjct: 938  LITEYCDWGDLKQFLLATRNDNGRGRGTRVPALALSQKLGMGQQVAAGMEALSNQGLVHG 1117

Query: 669  RLKSRNCVVDGRFVLKVTDHGHGRLLEAQRVLPEPPSAEDQLWTAPELLRDPSLERRGTL 728
             L +RN ++  R  LKV        + A    P         W  PE +    LE   T 
Sbjct: 1118 DLAARNVLLTSRMQLKVARPALSGDVYASEYYPLHQRLVPLRWLPPEGV----LEDSATT 1285

Query: 729  AGDVFSLAIIMQEVV-CRSTPYAMLELTPEEVIQRVRSPPPLCRPLVSMDQAPMECIQLM 787
             GDV++  + + EV+     PY +  ++ EEV++ ++      +  +    AP   + L+
Sbjct: 1286 CGDVWAFGVFLWEVLQLADLPYRL--MSDEEVLRSLQH----SQAALDSPDAPPALLSLL 1447

Query: 788  TQCWAEHPELRP 799
             +C A+ P  RP
Sbjct: 1448 QRCTAQQPSQRP 1483
>29581
          Length = 1278

 Score = 46.2 bits (108), Expect = 6e-05,   Method: Compositional matrix adjust.
 Identities = 43/158 (27%), Positives = 71/158 (44%), Gaps = 1/158 (0%)
 Frame = -2

Query: 587  LRELRHENVALYLGLFLAGTADSPATPGEGILAVVSEHCARGSLHDLLAQREIKLDWMFK 646
            L  LRH+N+     + +  + DS        L +V E+C +  L  LL            
Sbjct: 1193 LLNLRHQNIVQLQEVVVGKSLDS--------LFLVMEYCEQ-DLASLLDNMPAPFSESQV 1041

Query: 647  SSLLLDLIKGMRYLHHRGVAHGRLKSRNCVVDGRFVLKVTDHGHGRLL-EAQRVLPEPPS 705
              ++L L+KG+RYLH   + H  LK  N ++  +  +K+ D G  R   + Q+  P  P 
Sbjct: 1040 KCIVLQLLKGLRYLHEAFIIHRDLKVSNLLMTDKGCVKIADFGLARNYGKPQK--PMTPK 867

Query: 706  AEDQLWTAPELLRDPSLERRGTLAGDVFSLAIIMQEVV 743
                 + APELL      +  + A D++S   I+ E++
Sbjct: 866  VVTLWYRAPELLFG---SKTHSTAIDMWSAGCILGELL 762
>11780
          Length = 1713

 Score = 42.4 bits (98), Expect(2) = 1e-04,   Method: Compositional matrix adjust.
 Identities = 46/175 (26%), Positives = 73/175 (41%), Gaps = 8/175 (4%)
 Frame = +3

Query: 556 GLYEGDWVWLKKFP----GEHHMAIRPATKTAFSKLRELRHENVALYLGLFLAGTADSPA 611
           G+Y G  V +K+      GE       +  T+      LRH+N+   +G+ L        
Sbjct: 654 GMYRGQPVAIKQLKDKDRGEQSFLQEASVMTS------LRHDNLVRLIGVVL-------- 791

Query: 612 TPGEGILAVVSEHCARGSLHDLLAQRE----IKLDWMFKSSLLLDLIKGMRYLHHRGVAH 667
             GE I  +V+E   +G+L + L  R      K D +   +   D    M YL  + + H
Sbjct: 792 --GETIF-LVTEFMGKGNLVEYLRSRGRSVITKKDQI---NFATDTCAAMEYLESKRLVH 953

Query: 668 GRLKSRNCVVDGRFVLKVTDHGHGRLLEAQRVLPEPPSAEDQLWTAPELLRDPSL 722
             L +RN +V      KV+D G  +  +  +   + P      WTAPE LR+  +
Sbjct: 954 RDLAARNVLVHDDGKAKVSDFGLAKFGDFSQTSVKFPIK----WTAPEALRENKI 1106

 Score = 22.7 bits (47), Expect(2) = 1e-04,   Method: Compositional matrix adjust.
 Identities = 23/88 (26%), Positives = 37/88 (42%), Gaps = 1/88 (1%)
 Frame = +1

Query: 725  RGTLAGDVFSLAIIMQEVVCRS-TPYAMLELTPEEVIQRVRSPPPLCRPLVSMDQAPMEC 783
            + T   D++S  I++ E+      PY  + LT  +V+  V     +  P    +  P E 
Sbjct: 1102 KFTSKSDMWSFGILLWEIYSFGRVPYPRIPLT--DVVMHVERGYRMEAP----EGCPPEI 1263

Query: 784  IQLMTQCWAEHPELRPSMDLTFDLFKSI 811
              +M Q W   P  RP+       FKS+
Sbjct: 1264 YSIMKQAWELDPNERPT-------FKSV 1326
>18921
          Length = 697

 Score = 45.4 bits (106), Expect = 1e-04,   Method: Composition-based stats.
 Identities = 43/161 (26%), Positives = 74/161 (45%), Gaps = 6/161 (3%)
 Frame = +2

Query: 618 LAVVSEHCARGSLHDLLAQREIKLDWMFKSSLLLDLIKGMRYLHHRGVAHGRLKSRNCVV 677
           L +V E+C  GS+ D++  R   L     +++L   +KG+ YLH R   H  +K+ N ++
Sbjct: 239 LWIVMEYCGAGSVSDIMRLRNKTLVEREIATILYYTLKGLXYLHSRRKIHRDIKAGNILL 418

Query: 678 DGRFVLKVTDHG-HGRLLE--AQR--VLPEPPSAEDQLWTAPELLRDPSLERRGTLAGDV 732
           +     K+ D G  G+L +  A+R  V+  P       W APE++++   +       D+
Sbjct: 419 NNEGHAKLADFGVAGQLTDTMAKRNTVIGTP------YWMAPEVIQEIGYD----CVADI 568

Query: 733 FSLAIIMQEVVCRSTPYAMLELT-PEEVIQRVRSPPPLCRP 772
           +SL I   E+     P     +   +       +PPPL  P
Sbjct: 569 WSLGITALEMAEGKPPVMETSIL*GQSS*FPTNAPPPLPFP 691
>01756
          Length = 1858

 Score = 44.3 bits (103), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 42/164 (25%), Positives = 72/164 (43%), Gaps = 4/164 (2%)
 Frame = -3

Query: 587  LRELRHENVALYLGLFLAGTADSPATPGEGILAVVSEHCARGSLHDLLAQREIKLDWMFK 646
            L+ L HENV   + +    T  + A   + +  +V E C    L  LL+   +  +    
Sbjct: 1583 LQLLNHENVVDLIEI--CSTKATSANRYKSMFYLVFEFCEH-DLAGLLSNMSVVFNLPEI 1413

Query: 647  SSLLLDLIKGMRYLHHRGVAHGRLKSRNCVVDGRFVLKVTDHGHGRLLEAQRVLPEPPSA 706
              ++  L+ G+ Y+H   + H  +K+ N ++  + VLK+ D G  R       L +P   
Sbjct: 1412 KEVMKQLMNGLYYIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVN--LRQPNRY 1239

Query: 707  EDQ---LWTA-PELLRDPSLERRGTLAGDVFSLAIIMQEVVCRS 746
             ++   LW   PELL     +R  + A D +    IM E+  R+
Sbjct: 1238 TNRVVTLWYRPPELLLG---DRNYSTAIDQWGAGCIMAEMWTRN 1116
>07940
          Length = 1336

 Score = 44.3 bits (103), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 31/98 (31%), Positives = 48/98 (48%), Gaps = 3/98 (3%)
 Frame = -3

Query: 648 SLLLDLIKGMRYLHHRGVAHGRLKSRNCVVDGRFVLKVTDHGHGRLLEAQRVLPEPPSAE 707
           S    + +GM YL  +   H  L +RN +V   +VLK+ D G  R L  Q+      + +
Sbjct: 335 SYAYQVARGMEYLASKQCIHRDLAARNVLVAEEYVLKIADFGLTRNL--QQFDYYRKTTD 162

Query: 708 DQL---WTAPELLRDPSLERRGTLAGDVFSLAIIMQEV 742
            +L   W APE L D    R+ T   DV+S  +++ E+
Sbjct: 161 GRLPVKWMAPEALFD----RKYTSKSDVWSYGVLLWEI 60
>18996
          Length = 491

 Score = 44.3 bits (103), Expect = 3e-04,   Method: Composition-based stats.
 Identities = 41/145 (28%), Positives = 62/145 (42%), Gaps = 11/145 (7%)
 Frame = +2

Query: 667 HGRLKSRNCVVDGRFVLKVTDHGHGRLLEA--------QRVLPEPPSAEDQLWTAPELLR 718
           H  L +RN +VD R  +K++D G  +   A        QR +P         W +PE + 
Sbjct: 5   HRDLAARNILVD-RSCVKISDFGLAQFANADGYYYGISQRDIPIK-------WYSPEAIE 160

Query: 719 DPSLERRGTLAGDVFSLAIIMQEVVCRSTPYAML---ELTPEEVIQRVRSPPPLCRPLVS 775
                       DV+S  + + E+  R     +L   +LT EE + R+R    L +P + 
Sbjct: 161 TCKFSSYS----DVWSYGVTLFEMFSRGEIPNLLPGHDLTQEEFLNRLRKGERLPKPELC 328

Query: 776 MDQAPMECIQLMTQCWAEHPELRPS 800
            D    E   LM  CW E P+ RP+
Sbjct: 329 SDFVYSE---LMRPCWHEMPKSRPT 394
>04591
          Length = 1117

 Score = 43.9 bits (102), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 43/162 (26%), Positives = 73/162 (45%), Gaps = 2/162 (1%)
 Frame = -2

Query: 587  LRELRHENVALYLGLFLAGTADSPATPGEGILAVVSEHCARGSLHDLLAQREIKLDWMFK 646
            L++L HENV     +    T   P    +    ++ E+C    L  LL    +K     K
Sbjct: 1059 LQQLEHENVVQLQEI--CHTQAGPYNRYKSTFYLIFEYCDY-DLAGLLNNLRVKFSLADK 889

Query: 647  SSLLLDLIKGMRYLHHRGVAHGRLKSRNCVVDGRFVLKVTDHGHGR-LLEAQRVLPEPPS 705
             +L+  L+ G+ Y+H + + H  +K+ N ++    VLK+ D G  R  ++++R+     +
Sbjct: 888  KNLMSQLLNGLFYIHTKQILHRDIKAANILLTRDGVLKLADFGLSRPWVKSKRLTNRVVT 709

Query: 706  AEDQLWT-APELLRDPSLERRGTLAGDVFSLAIIMQEVVCRS 746
                LW   PELL     ER      D++ +  IM E+  R 
Sbjct: 708  ----LWYRPPELLLG---EREYGPEIDMWGVGCIMAEMWSRK 604
>14116
          Length = 1017

 Score = 43.1 bits (100), Expect = 6e-04,   Method: Compositional matrix adjust.
 Identities = 29/99 (29%), Positives = 50/99 (50%), Gaps = 2/99 (2%)
 Frame = -1

Query: 651 LDLIKGMRYLHHRGVAHGRLKSRNCVVDGRFVLKVTDHGHGR-LLEAQRVLPEPPSAEDQ 709
           +D+ +GM YL      H  L +RNC++D  F +KV D G  R + E +    E   A+  
Sbjct: 300 VDIARGMDYLAGLKFVHRDLAARNCMLDEDFHVKVADFGLARDIYEKEYYSSENKKAKLP 121

Query: 710 L-WTAPELLRDPSLERRGTLAGDVFSLAIIMQEVVCRST 747
           + W A E L   + + +     DV+S  +++ E++ R +
Sbjct: 120 VKWMALESLEKGNYDSK----TDVWSYGVVLWELLTRGS 16
>17637
          Length = 447

 Score = 40.8 bits (94), Expect = 0.003,   Method: Composition-based stats.
 Identities = 35/129 (27%), Positives = 51/129 (39%), Gaps = 2/129 (1%)
 Frame = +1

Query: 674 NCVVDGRFVLKVTDHGHGR-LLEAQRVLPEPPSAEDQLWTAPELLRDPSLERRGTLAGDV 732
           NCV+D +  +K+TD    R L                 W + E L+            DV
Sbjct: 1   NCVIDDQLRVKLTDSALSRDLFSGDYNCLGDGEYRPIKWLSLEALQKSHYNE----GSDV 168

Query: 733 FSLAIIMQEVVCRST-PYAMLELTPEEVIQRVRSPPPLCRPLVSMDQAPMECIQLMTQCW 791
           +S  ++M E+      PYA  E+ P E+   ++    L +P       P E   +M  CW
Sbjct: 169 WSFGVLMWEMCTLGKLPYA--EIDPYEMEHYLKDGYRLAQPF----NCPDELFTIMAYCW 330

Query: 792 AEHPELRPS 800
           A  P  RPS
Sbjct: 331 ASMPAERPS 357
>09606
          Length = 1300

 Score = 40.0 bits (92), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 40/170 (23%), Positives = 73/170 (42%), Gaps = 25/170 (14%)
 Frame = -3

Query: 618 LAVVSEHCARGSLHDLLAQREIKLDWMFKSSLLLDLIKGMRYLHHRGVAHGRLKSRNCVV 677
           L +V E C  GSL D+LAQ    L         + L+ G+ Y+H  G+    L+    ++
Sbjct: 908 LWLVVELCTGGSLADILAQDH-HLPETSIRDFGIHLVTGLHYIHSLGILFHDLRPSKVLL 732

Query: 678 DGRFVLKVTDHG----HGRLLE-----------------AQRVLPEPPSAEDQLWTAPEL 716
           D   VLK  D G     G  LE                 A+ ++ + P++    + APE+
Sbjct: 731 DTSGVLKFADFGLSKVEGENLEELFFKFAEAGDQWNIQSAEEMMKQVPTSGSPTYMAPEV 552

Query: 717 LR--DPSLERRGTLAGDVFSLAIIMQEVVCRSTPY--AMLELTPEEVIQR 762
            +  +PS      +  D+++L  +  E+     P+     ++T ++V+ +
Sbjct: 551 FQGAEPS------IMSDLWALGCVFYEMFSGHPPFLGETYDITKDKVLNK 420
>07836
          Length = 1478

 Score = 39.3 bits (90), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 49/167 (29%), Positives = 78/167 (46%), Gaps = 14/167 (8%)
 Frame = -1

Query: 590  LRHENVALYLGLFLAGTADSPATPGEGILAVVSEHCARGSLHDLLAQREIKLDWMFKSSL 649
            LRHEN+   LG F+A  AD   T     L +++++   GSLHD L  R +    M   +L
Sbjct: 1394 LRHENI---LG-FIA--ADIKGTGSWTQLFLITDYHENGSLHDYLLSRVLDSSEML--AL 1239

Query: 650  LLDLIKGMRYLH-----HRG---VAHGRLKSRNCVVDGRFVLKVTDHGHG--RLLEAQRV 699
                I G+ +LH      RG   +AH  +KS+N +V       + D G     + E+  V
Sbjct: 1238 AHSAICGLAHLHIEIFGTRGKPAIAHRDIKSKNILVKKNGTCCIADLGLAVRYISESNEV 1059

Query: 700  LPEP-PSAEDQLWTAPELLRDPSLERRGTLA---GDVFSLAIIMQEV 742
               P P    + + APE+L +  L  +   A    D+++  ++M E+
Sbjct: 1058 DVAPNPRQGTKRYMAPEVL-EMLLNVKNFDAFKQADMYAFGLVMWEI 921
>19094
          Length = 898

 Score = 35.4 bits (80), Expect = 0.13,   Method: Composition-based stats.
 Identities = 33/120 (27%), Positives = 59/120 (49%), Gaps = 5/120 (4%)
 Frame = +1

Query: 628 GSLHDLLAQREIKLDWMFKSSLLLDLIKGMRYLHHRGVAHGRLKSRNCVVDGRFVLKVTD 687
           GS+ D++  R   L     +++L   +KG+ YLH R   H  +K+ N +++     K+ D
Sbjct: 10  GSVSDIMRLRNKTLVEREIATILYYTLKGL*YLHSRRKIHRDIKAGNILLNNEGHAKLAD 189

Query: 688 HG-HGRLLE--AQR--VLPEPPSAEDQLWTAPELLRDPSLERRGTLAGDVFSLAIIMQEV 742
            G  G+L +  A+R  V+  P       W APE++++   +       D++SL I   E+
Sbjct: 190 FGVAGQLTDTMAKRNTVIGTP------YWMAPEVIQEIGYD----CVADIWSLGITALEM 339
>27546
          Length = 426

 Score = 35.4 bits (80), Expect = 0.14,   Method: Composition-based stats.
 Identities = 16/50 (32%), Positives = 25/50 (50%)
 Frame = -1

Query: 643 WMFKSSLLLDLIKGMRYLHHRGVAHGRLKSRNCVVDGRFVLKVTDHGHGR 692
           W F+      + K ++YLH   +AH  LK  N ++  R  +K+ D G  R
Sbjct: 165 WFFQ------MAKALQYLHSHDIAHRDLKCENILLSKRLNVKIADFGFAR 34
>30464
          Length = 977

 Score = 34.3 bits (77), Expect = 0.25,   Method: Compositional matrix adjust.
 Identities = 18/37 (48%), Positives = 22/37 (59%)
 Frame = +3

Query: 669 RLKSRNCVVDGRFVLKVTDHGHGRLLEAQRVLPEPPS 705
           R++  +C V GRF L VT H H   L A+R LP P S
Sbjct: 192 RVEGHDCDVAGRFPLHVTQHTHQVCLIARRPLPRPSS 302
>04138
          Length = 800

 Score = 32.7 bits (73), Expect = 0.91,   Method: Compositional matrix adjust.
 Identities = 42/180 (23%), Positives = 73/180 (40%), Gaps = 8/180 (4%)
 Frame = +1

Query: 657 MRYLHHRGVAHGRLKSRNCVVDGRFVLKVTDHGHGRLLEAQRVLPEPPSAEDQ---LWTA 713
           + Y+H   + H  +K+ N ++  + VLK+ D G  R       L +P    ++   LW  
Sbjct: 52  LYYIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVN--LRQPNRYTNRVVTLWYR 225

Query: 714 -PELLRDPSLERRGTLAGDVFSLAIIMQEVVCRSTPYAMLELTPEEVIQRVRSPPPLCRP 772
            PELL     +R  + A D +    IM E+  R+                     P+ + 
Sbjct: 226 PPELLLG---DRNYSTAIDQWGAGCIMAEMWTRN---------------------PIMQG 333

Query: 773 LVSMDQAPMECIQLMTQ-CWAEHPELRP---SMDLTFDLFKSINKGRKTNIIDSMLRMLE 828
               +Q     + L+TQ C +  PE+ P    + +   +  ++  GRK  I D   R+L+
Sbjct: 334 TTEQNQ-----LTLITQLCGSITPEVWPGVTQLSMYHQIKGALAAGRKNIIRDRFARILK 498
>00392
          Length = 668

 Score = 32.0 bits (71), Expect = 1.3,   Method: Composition-based stats.
 Identities = 47/197 (23%), Positives = 81/197 (41%), Gaps = 6/197 (3%)
 Frame = +3

Query: 575 AIRPATKTAFSKLRELRHENVALYLGLFLAGTADSPATPGEGILAVVSEHCARGSLHDLL 634
           A R   K     L+EL+H N+  +   +     +        ++ +V+E    G+L   L
Sbjct: 57  AERQRFKEEAEMLKELQHPNIVRFFDYW-----EEHNHRNRKVIILVTELMTSGTLKTYL 221

Query: 635 AQREIKLDWMFKSSLLLDLIKGMRYLHHRG--VAHGRLKSRNCVVDGRF-VLKVTDHGHG 691
            +R  K +     +    ++KG+ +LH R   V H  LK  N  + G    +K+ D G  
Sbjct: 222 -KRFKKPNVKILKNWCRQVLKGLYFLHTRTPPVIHRDLKCDNIFITGPTGSVKIGDLGLA 398

Query: 692 RLLE---AQRVLPEPPSAEDQLWTAPELLRDPSLERRGTLAGDVFSLAIIMQEVVCRSTP 748
            L     A+ V+  P       + APE+  +   E     A DV++  + M E+     P
Sbjct: 399 TLKNQSFAKSVIGTPE------FMAPEMYEEHYDE-----AVDVYAFGMCMLEMASSEYP 545

Query: 749 YAMLELTPEEVIQRVRS 765
           Y+       ++ +RV S
Sbjct: 546 YSECS-NAAQIYKRVTS 593
>37602
          Length = 804

 Score = 31.6 bits (70), Expect = 1.9,   Method: Composition-based stats.
 Identities = 20/76 (26%), Positives = 35/76 (46%), Gaps = 6/76 (7%)
 Frame = -1

Query: 618 LAVVSEHCARGSLHDL------LAQREIKLDWMFKSSLLLDLIKGMRYLHHRGVAHGRLK 671
           L +  E+C  GS+ D+      L + +I         +  + +KG+ YLH RG  H  +K
Sbjct: 294 LWIAMEYCGGGSMQDIYHVTGPLTEPQIAF-------VCRETLKGLHYLHRRGKMHRDIK 136

Query: 672 SRNCVVDGRFVLKVTD 687
             N ++     +K+ D
Sbjct: 135 GANILLTEEGDVKLAD 88
>11185
          Length = 473

 Score = 30.4 bits (67), Expect = 4.2,   Method: Compositional matrix adjust.
 Identities = 26/119 (21%), Positives = 50/119 (42%), Gaps = 23/119 (19%)
 Frame = +1

Query: 651 LDLIKGMRYLHHRGVAHGRLKSRNCVVDGRFVLKVTDHG----HGRLLE----------- 695
           + L+ G+ Y+H  G+    L+    ++D   VLK  D G     G  LE           
Sbjct: 22  IHLVTGLHYIHSLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEAGD 201

Query: 696 ------AQRVLPEPPSAEDQLWTAPELLR--DPSLERRGTLAGDVFSLAIIMQEVVCRS 746
                 A+ ++ + P++    + APE+ +  +PS      +  D+++L  +  E+   S
Sbjct: 202 QWNIQSAEEMMKQVPTSGSPTYMAPEVFQGAEPS------IMSDLWALGCVFYEMFSGS 360
>11995
          Length = 882

 Score = 30.0 bits (66), Expect = 5.1,   Method: Composition-based stats.
 Identities = 19/57 (33%), Positives = 30/57 (52%), Gaps = 3/57 (5%)
 Frame = +1

Query: 835 EDLIRERTEELEQEKQKTDRLLTQM---LPPSVAEALKMGTSVEPEYFEEVTLYFSD 888
           ED+ +E     E+  + T++   Q    L P VAEALK G  V  + FE++  + +D
Sbjct: 142 EDVTQEAEATEEKPPEHTEKTREQREADLVPKVAEALKFGIDVIDQAFEKLDSHVAD 312
>31768
          Length = 356

 Score = 30.0 bits (66), Expect = 5.2,   Method: Composition-based stats.
 Identities = 13/23 (56%), Positives = 16/23 (69%)
 Frame = +1

Query: 1037 GFQMECRGRTELKGKGIEDTYWL 1059
            GF +E RG  E+KGKG  DT+ L
Sbjct: 19   GFALEKRGHVEVKGKGQMDTFLL 87
>13066
          Length = 551

 Score = 29.6 bits (65), Expect = 6.9,   Method: Composition-based stats.
 Identities = 13/37 (35%), Positives = 19/37 (51%)
 Frame = +3

Query: 653 LIKGMRYLHHRGVAHGRLKSRNCVVDGRFVLKVTDHG 689
           +   + YLH   VAH  LK  N ++   F +K+ D G
Sbjct: 303 MTTALNYLHSYDVAHRDLKCENILLSSHFNVKLADFG 413
>19708
          Length = 416

 Score = 29.6 bits (65), Expect = 7.0,   Method: Composition-based stats.
 Identities = 12/20 (60%), Positives = 14/20 (70%)
 Frame = -2

Query: 688 HGHGRLLEAQRVLPEPPSAE 707
           H HGRLLE  + LP PPS +
Sbjct: 295 HDHGRLLELIKTLPLPPSLQ 236
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|188219589|ref|NP_034851.2| lamin B1 [Mus musculus]
         (588 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

02016                                                                 211   5e-55
19956                                                                 102   5e-22
10849                                                                  84   1e-16
26996                                                                  70   2e-12
11243                                                                  67   2e-11
02029                                                                  52   9e-07
17996                                                                  49   5e-06
04319                                                                  45   9e-05
>02016
          Length = 3061

 Score =  211 bits (538), Expect = 5e-55,   Method: Compositional matrix adjust.
 Identities = 123/380 (32%), Positives = 205/380 (53%), Gaps = 5/380 (1%)
 Frame = +3

Query: 167 LKDQIAQLEASLSAAKKQLADETLLKVDLENRCQSLTEDLEFRKNMYEEEINETRRKHET 226
           L+ ++A LE  L+  KKQL +ETLL+VDLENR QSL E++ F+  +YE+E+ E+R +   
Sbjct: 117 LRAEVAGLEKQLAKLKKQLEEETLLRVDLENRLQSLKEEINFKSQVYEQELEESRVRTTV 296

Query: 227 RLVEVDSGRQIEYEYKLAQALHEMREQHDAQVRLYKEELEQTYHAKLENARLSSEMNTST 286
            + +VD   + EYE +L +AL E+R QH++ ++  + ELE  Y  K+ + +  +  + S 
Sbjct: 297 EIEQVDGRLEHEYEQRLLEALREIRAQHESDLQTVRVELETLYENKIADLKAQANRSNSA 476

Query: 287 VNSAREELMESRMRIESLSSQLSNLQKESRACLERIQELEDMLAKERDNSRRMLSDRERE 346
             SA EEL  +R R + L ++L+ L+ E+     RI +LE  LA+ER+  R  L+ ++ E
Sbjct: 477 SGSAWEELRITRKRADDLGAELAKLKAETAGFELRISDLESQLAREREEFRLRLAQKDDE 656

Query: 347 MAEIRDQMQQQLSDYEQLLDVKLALDMEISAYXXXXXXXXXXXXXXXXXXXXXXXXXXXX 406
           +AE+R  +++Q+ +Y  LLD+K+ LD EI AY                            
Sbjct: 657 LAELRLTLEEQMQEYSDLLDIKIRLDREIDAYRKLLESEESRLNISLDASQSSQTSRSPA 836

Query: 407 XXXXXXXXGKRKR-----XXXXXXXXXXXXXXXXXXXXTGNVCIEEIDVDGKFIRLKNTS 461
                    KR+R                          GNV I E+D +GKFI+L N  
Sbjct: 837 RATPSGRGTKRRRVDISEAVEEYSQKSSSSGFARAASAKGNVNIAEVDSEGKFIKLTNEG 1016

Query: 462 EQDQPMGGWEMIRKIGDTSVSYKYTSRYVLKAGQTVTVWAANAGVTASPPTDLIWKNQNS 521
            +D  +G W++    G+    +K+    V+KAG+TVT+W++++  T +PP+D++ K +  
Sbjct: 1017SKDVAIGSWQLQHTAGEQDTKFKFYRSLVVKAGKTVTIWSSDSDTTHNPPSDIVMKGKR- 1193

Query: 522 WGTGEDVKVILKNSQGEEVA 541
           W   +++K +L ++  EE+A
Sbjct: 1194WFVADEMKTVLLDTDSEEMA 1253
>19956
          Length = 536

 Score =  102 bits (253), Expect = 5e-22,   Method: Compositional matrix adjust.
 Identities = 61/177 (34%), Positives = 98/177 (55%)
 Frame = -3

Query: 52  RSLETENSALQLQVTEREEVRGRELTGLKALYEXXXXXXXXXXXXXXXXXXKLQIELGKF 111
           R LE EN+ L  Q+   EE   RE++ +K LYE                  ++QIE   F
Sbjct: 534 RYLEAENNRLSTQIQSTEETVKREVSSVKNLYENELSDARKVLDETAKEKARVQIEASTF 355

Query: 112 KAEHDQLLLNYAKKESDLSGAQIKLREYEAALNSKDAALATALGDKKSLEGDLEDLKDQI 171
           K +++ +L  Y +++ + SGA+ ++   E  L    A L  A   +  L+ D+  L+ Q+
Sbjct: 354 KTKYEDMLAKYKQRDREASGAEQRVENLEVQLADLSAKLNDADAARARLQKDMSGLRSQL 175

Query: 172 AQLEASLSAAKKQLADETLLKVDLENRCQSLTEDLEFRKNMYEEEINETRRKHETRL 228
           +  E  L  AK+Q+ +ETLL+VDLENR QSL E+L+F+  +YE+E+ E R +  T++
Sbjct: 174 SSQEQQLGTAKQQIEEETLLRVDLENRVQSLKEELQFKAQLYEQELEEVRVRSTTKI 4
>10849
          Length = 1392

 Score = 84.3 bits (207), Expect = 1e-16,   Method: Compositional matrix adjust.
 Identities = 41/101 (40%), Positives = 61/101 (60%)
 Frame = +3

Query: 441 GNVCIEEIDVDGKFIRLKNTSEQDQPMGGWEMIRKIGDTSVSYKYTSRYVLKAGQTVTVW 500
           G + I E+D +GKFI+L NT  +D  +G W++    GD   ++K+    V+KA   VTVW
Sbjct: 81  GVMQISEVDPEGKFIKLTNTGSKDSSLGSWQVKHVAGDQETAFKFHRSLVVKADSCVTVW 260

Query: 501 AANAGVTASPPTDLIWKNQNSWGTGEDVKVILKNSQGEEVA 541
           +A+   T SPPTD++ K +  W   +++K  L NS  EEVA
Sbjct: 261 SADTEATHSPPTDVVMKGKR-WFVNDEMKTTLFNSDEEEVA 380
>26996
          Length = 386

 Score = 70.1 bits (170), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 37/63 (58%), Positives = 45/63 (71%)
 Frame = -1

Query: 22  PLSPTRLSRLQEKEELRELNDRLAVYIDKVRSLETENSALQLQVTEREEVRGRELTGLKA 81
           P SPTR +R QE+E L+ LNDRLA YID+VR LE ENS L  QV   EE+  RE++ +K 
Sbjct: 257 PPSPTRSTRQQEQESLQGLNDRLANYIDRVRFLEAENSRLSTQVQSTEEIVKREVSSVKN 78

Query: 82  LYE 84
           LYE
Sbjct: 77  LYE 69
>11243
          Length = 828

 Score = 67.4 bits (163), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 57/205 (27%), Positives = 106/205 (51%), Gaps = 1/205 (0%)
 Frame = -2

Query: 175 EASLSAAKKQLADETLLKVDLENRCQSLTEDLEFRKNMYEEEINETRRKHETRL-VEVDS 233
           E+ +   ++ L + TL K DLE   +SL E+L + K  +EEE+   R      + V+VDS
Sbjct: 824 ESDIVGLRRVLDELTLNKTDLELEIESLKEELIYLKKNHEEELAVVRSSARGNVDVQVDS 645

Query: 234 GRQIEYEYKLAQALHEMREQHDAQVRLYKEELEQTYHAKLENARLSSEMNTSTVNSAREE 293
              ++    LAQ + ++R Q+++ +   ++ELE  Y  + EN       NT+ + +++  
Sbjct: 644 APPVD----LAQIMXDVRSQYESMMEKNRQELEACYKGQSENLNHEVATNTAALQTSKTA 477

Query: 294 LMESRMRIESLSSQLSNLQKESRACLERIQELEDMLAKERDNSRRMLSDREREMAEIRDQ 353
           + + +  I+SL  +L +L     A    + E E     + ++ + M++  E E+  +R  
Sbjct: 476 ITDLKRTIQSLEIELQSLLSMKGALEGTLAETEAQYGAQLNHLQAMITQVEMELQNLRSD 297

Query: 354 MQQQLSDYEQLLDVKLALDMEISAY 378
              Q  +Y++LLD K  L+MEI+ Y
Sbjct: 296 ADHQSLEYKRLLDAKTRLEMEIATY 222
>02029
          Length = 1497

 Score = 51.6 bits (122), Expect = 9e-07,   Method: Compositional matrix adjust.
 Identities = 26/65 (40%), Positives = 38/65 (58%)
 Frame = +1

Query: 478 DTSVSYKYTSRYVLKAGQTVTVWAANAGVTASPPTDLIWKNQNSWGTGEDVKVILKNSQG 537
           D   ++K+    V+KA   VTVW+A+   T SPPTD++ K +  W   +++K  L NS  
Sbjct: 1   DQETAFKFHRSLVVKADSCVTVWSADTEATHSPPTDVVMKGKR-WFVNDEMKTTLFNSDE 177

Query: 538 EEVAQ 542
           EEVA 
Sbjct: 178 EEVAN 192
>17996
          Length = 475

 Score = 48.9 bits (115), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 24/72 (33%), Positives = 38/72 (52%), Gaps = 4/72 (5%)
 Frame = +2

Query: 483 YKYTSRYVLKAGQTVTVWAANAGVT----ASPPTDLIWKNQNSWGTGEDVKVILKNSQGE 538
           Y++  R    A  T+TV++   G T     +PPTD++WK Q  WG+G +   IL  + G+
Sbjct: 5   YRFPPRTKFAANSTLTVYS---GTTDRKMHNPPTDIVWKEQQKWGSGPECTTILCRANGQ 175

Query: 539 EVAQRSTVFKTT 550
            VA  +   + T
Sbjct: 176 AVAWTTAAHRFT 211
>04319
          Length = 496

 Score = 45.1 bits (105), Expect = 9e-05,   Method: Composition-based stats.
 Identities = 21/62 (33%), Positives = 34/62 (54%)
 Frame = +3

Query: 480 SVSYKYTSRYVLKAGQTVTVWAANAGVTASPPTDLIWKNQNSWGTGEDVKVILKNSQGEE 539
           ++ Y + S  V+  GQ++ +WA  A  +   P DL+++ + SWGTG  +   L N   EE
Sbjct: 63  TMVYTFPSHTVIPLGQSLKIWAKGAS-SEKKPGDLVFEGEFSWGTGTQITTTLINDNNEE 239

Query: 540 VA 541
            A
Sbjct: 240 KA 245
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|41350312|ref|NP_038636.2| nascent
polypeptide-associated complex alpha subunit isoform b [Mus musculus]
         (215 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

24263                                                                 207   2e-54
23102                                                                 152   1e-37
23388                                                                  72   2e-13
30771                                                                  57   6e-09
>24263
          Length = 1042

 Score =  207 bits (528), Expect = 2e-54,   Method: Compositional matrix adjust.
 Identities = 112/158 (70%), Positives = 123/158 (77%), Gaps = 1/158 (0%)
 Frame = +2

Query: 59  IDEEPVSKAKQSRSEKKARKAMSKLGLRQVTGVTRVTIRKSKNILFVITKPDVYKSPASD 118
           + EE VSKAKQSRSEKKARKAMSKLGL+ VTGVTRVTIRKSKNILFVI +PDVYKSPASD
Sbjct: 218 LTEELVSKAKQSRSEKKARKAMSKLGLKAVTGVTRVTIRKSKNILFVINRPDVYKSPASD 397

Query: 119 TYIVFGEAKIEDLSQQAQLAAAEKFKVQGEA-VSNIQENXXXXXXXXXXXXXXXXXXXXX 177
           TYIVFGEAKIEDL+QQAQ+AAAEKF+ +  A   +I                        
Sbjct: 398 TYIVFGEAKIEDLNQQAQMAAAEKFRDKPPAGPGDIPSTVSQPIQEESEEEEEEDETGVE 577

Query: 178 XKDIELVMSQANVSRAKAVRALKNNSNDIVNAIMELTM 215
            KDIELVMSQANVS++KAVRALKNN+NDIVNAIMELTM
Sbjct: 578 AKDIELVMSQANVSKSKAVRALKNNNNDIVNAIMELTM 691
>23102
          Length = 477

 Score =  152 bits (384), Expect = 1e-37,   Method: Compositional matrix adjust.
 Identities = 81/119 (68%), Positives = 90/119 (75%)
 Frame = -1

Query: 26  GTESDSDESVPELEEQDSXXXXXXXXXXXXXXEIDEEPVSKAKQSRSEKKARKAMSKLGL 85
           G+ESDS E +PELEE D+              ++    VSKAKQSR EKKARK M KLGL
Sbjct: 429 GSESDS-EIIPELEEADTGTTQLSGGATGLPIDV----VSKAKQSRGEKKARKIMLKLGL 265

Query: 86  RQVTGVTRVTIRKSKNILFVITKPDVYKSPASDTYIVFGEAKIEDLSQQAQLAAAEKFK 144
           +Q+ GV RVTIRKSKNILFVI  PDVYK+P SDTYIVFGEAKIEDLSQQAQ+AAAEKFK
Sbjct: 264 KQIQGVNRVTIRKSKNILFVINNPDVYKNPHSDTYIVFGEAKIEDLSQQAQVAAAEKFK 88
>23388
          Length = 491

 Score = 71.6 bits (174), Expect = 2e-13,   Method: Compositional matrix adjust.
 Identities = 34/37 (91%), Positives = 37/37 (100%)
 Frame = +2

Query: 179 KDIELVMSQANVSRAKAVRALKNNSNDIVNAIMELTM 215
           KDIELVMSQANVS++KAVRALKNN+NDIVNAIMELTM
Sbjct: 65  KDIELVMSQANVSKSKAVRALKNNNNDIVNAIMELTM 175
>30771
          Length = 493

 Score = 57.0 bits (136), Expect = 6e-09,   Method: Compositional matrix adjust.
 Identities = 29/37 (78%), Positives = 32/37 (86%)
 Frame = +2

Query: 60  DEEPVSKAKQSRSEKKARKAMSKLGLRQVTGVTRVTI 96
           + E  +K KQSRSEKKARKAMSKLGL+ VTGVTRVTI
Sbjct: 383 EGEMGAKGKQSRSEKKARKAMSKLGLKAVTGVTRVTI 493
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|47271396|ref|NP_034439.2| GNAS complex locus XLas
[Mus musculus]
         (1133 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

11965                                                                 209   4e-54
29196                                                                 109   4e-38
13527                                                                 137   3e-32
20516                                                                 104   2e-22
09827                                                                  47   3e-05
08153                                                                  45   2e-04
10862                                                                  42   0.001
18949                                                                  38   0.018
11378                                                                  33   0.70 
28331                                                                  30   5.0  
18208                                                                  30   5.0  
>11965
          Length = 3256

 Score =  209 bits (533), Expect = 4e-54,   Method: Compositional matrix adjust.
 Identities = 112/234 (47%), Positives = 143/234 (61%)
 Frame = +1

Query: 895  DEGVRACYERSNEYQLIDCAQYFLDKIDVIKQADYVPSDQDLLRCRVLTSGIFETKFQVD 954
            D GV+ C+ RSNEYQL D A+YFLD +D +   DY+P++QD+LR RV T+GI E  F   
Sbjct: 1    DSGVQDCFSRSNEYQLNDSAKYFLDDLDRLGTKDYMPTEQDILRTRVKTTGIVEVHFSFK 180

Query: 955  KVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVVASSSYNMVIREDNQTNRLQEALNLFKS 1014
             +NF +FDVGGQR ER+KWI CF DVTAIIF VA S Y+ V+ ED  TNR+QE+L LF S
Sbjct: 181  NLNFKLFDVGGQRSERKKWIHCFEDVTAIIFCVAMSEYDQVLHEDETTNRMQESLKLFDS 360

Query: 1015 IWNNRWLRTISVILFLNKQDLLAEKVLAGKSKIEDYFPEFARYTTPEDATPEPGEDPRVT 1074
            I NN+W    S+ILFLNK+DL  EK+   KS +   FPE+    T E+            
Sbjct: 361  ICNNKWFTDTSIILFLNKKDLFEEKI--KKSPLTVCFPEYTGKQTYEEVAA--------- 507

Query: 1075 RAKYFIRDEFLRISTASGDGRHYCYPHFTCAVDTENIRRVFNDCRDIIQRMHLR 1128
                +I+ +F      S     YC  H TCA DT NI+ VF+   D+I   +LR
Sbjct: 508  ----YIQAQF-EAKNKSSQKEIYC--HQTCATDTNNIQFVFDAVTDVIIANNLR 648
>29196
          Length = 431

 Score =  109 bits (273), Expect(2) = 4e-38,   Method: Composition-based stats.
 Identities = 47/74 (63%), Positives = 56/74 (75%)
 Frame = -2

Query: 956  VNFHMFDVGGQRDERRKWIQCFNDVTAIIFVVASSSYNMVIREDNQTNRLQEALNLFKSI 1015
            +NF +FDVGGQR ER+KWI CF DVTAIIF VA S Y+ V+ ED  TNR+QE+L LF SI
Sbjct: 223  LNFKLFDVGGQRSERKKWIHCFEDVTAIIFCVAMSEYDQVLHEDETTNRMQESLKLFDSI 44

Query: 1016 WNNRWLRTISVILF 1029
             NN+W    S+ILF
Sbjct: 43   CNNKWFTDTSIILF 2

 Score = 68.2 bits (165), Expect(2) = 4e-38,   Method: Composition-based stats.
 Identities = 34/75 (45%), Positives = 46/75 (61%)
 Frame = -1

Query: 886 YEHAKALWEDEGVRACYERSNEYQLIDCAQYFLDKIDVIKQADYVPSDQDLLRCRVLTSG 945
           +E A A +   G+   + RSNEYQL D A+YFLD +D +   DY P++QD+LR RV T+G
Sbjct: 425 HEAALARFRRSGM---FSRSNEYQLNDSAKYFLDDLDRLGAKDYQPTEQDILRTRVKTTG 255

Query: 946 IFETKFQVDKVNFHM 960
           I E  F   K  F +
Sbjct: 254 IVEVHFSFKKSEFQI 210
>13527
          Length = 1091

 Score =  137 bits (344), Expect = 3e-32,   Method: Compositional matrix adjust.
 Identities = 81/207 (39%), Positives = 116/207 (56%), Gaps = 2/207 (0%)
 Frame = -2

Query: 754  QKRADKKRSKLIDKQLEEEKMDYMCTHRLLLLGAGESGKSTIVKQMRILHVNGFNGEGGE 813
            ++RA  +RSK I+K L+E+ M      +LLLLGAGESGKSTIVKQM+I+H  GF  E  +
Sbjct: 1021 EERAAMERSKAIEKNLKEDGMQAAKDIKLLLLGAGESGKSTIVKQMKIIHEGGFTSEDNK 842

Query: 814  EDPQAARSNSDGEKATKVQDIKNNLKEAIETIVAAMSNLVPPVELANPENQFRVDYILSV 873
            +      SN+                +++  I+ AM  L  P    + E +     +L V
Sbjct: 841  QYRPVVFSNT---------------IQSLVAIIRAMGTLSIP--FGDNERESDAKMVLDV 713

Query: 874  M-NVPNFD-FPPEFYEHAKALWEDEGVRACYERSNEYQLIDCAQYFLDKIDVIKQADYVP 931
            +  + + + F  E     + LW D GV+ C+ RSNEYQL D A+YFLD +D +   DY+P
Sbjct: 712  IARMEDTEPFSEELLAAMERLWMDSGVQDCFSRSNEYQLNDSAKYFLDDLDRLGTKDYMP 533

Query: 932  SDQDLLRCRVLTSGIFETKFQVDKVNF 958
            ++QD+LR RV T+GI E  F    +NF
Sbjct: 532  TEQDILRTRVKTTGIVEVHFSFKNLNF 452
>20516
          Length = 534

 Score =  104 bits (260), Expect = 2e-22,   Method: Composition-based stats.
 Identities = 62/165 (37%), Positives = 92/165 (55%)
 Frame = +2

Query: 964  GGQRDERRKWIQCFNDVTAIIFVVASSSYNMVIREDNQTNRLQEALNLFKSIWNNRWLRT 1023
            GGQR +R+KW QCF  +T+I+F+ ASS ++ V+ ED +TNRLQE+ ++F++I NN+    
Sbjct: 80   GGQRSQRQKWYQCFVGITSILFLAASSEFDQVLMEDRKTNRLQESCDIFETIINNKSFSG 259

Query: 1024 ISVILFLNKQDLLAEKVLAGKSKIEDYFPEFARYTTPEDATPEPGEDPRVTRAKYFIRDE 1083
            +S+ILFLNK DLL +K  A   ++   F  F+  +     +        V  A    +  
Sbjct: 260  VSIILFLNKMDLLQDKN*A--CQLRRLFSRFSG*SQGH*CSQSI*ASA-V*FAPT*SKQT 430

Query: 1084 FLRISTASGDGRHYCYPHFTCAVDTENIRRVFNDCRDIIQRMHLR 1128
            F+               HFT A+DTENI+ VF D +D I   +LR
Sbjct: 431  FVH--------------HFTTAIDTENIKHVFQDVKDTILHDNLR 523
>09827
          Length = 1201

 Score = 47.4 bits (111), Expect = 3e-05,   Method: Composition-based stats.
 Identities = 28/80 (35%), Positives = 39/80 (48%)
 Frame = -3

Query: 956  VNFHMFDVGGQRDERRKWIQCFNDVTAIIFVVASSSYNMVIREDNQTNRLQEALNLFKSI 1015
            ++F ++DVGGQ   R  W   F +   +IFVV S          N   R+QEA      +
Sbjct: 983  ISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDS----------NDKERVQEAREELTRM 834

Query: 1016 WNNRWLRTISVILFLNKQDL 1035
             N   LR   +++F NKQDL
Sbjct: 833  LNEDELRDAVLLVFANKQDL 774
>08153
          Length = 1703

 Score = 45.1 bits (105), Expect = 2e-04,   Method: Composition-based stats.
 Identities = 27/80 (33%), Positives = 38/80 (47%)
 Frame = +1

Query: 956  VNFHMFDVGGQRDERRKWIQCFNDVTAIIFVVASSSYNMVIREDNQTNRLQEALNLFKSI 1015
            ++F ++DVGGQ   R  W   F +   +IFVV S          N   R+ EA      +
Sbjct: 214  ISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDS----------NDRERINEAKEELARM 363

Query: 1016 WNNRWLRTISVILFLNKQDL 1035
             N   LR   +++F NKQDL
Sbjct: 364  LNEDDLRDAIILVFANKQDL 423
>10862
          Length = 2896

 Score = 42.0 bits (97), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 26/84 (30%), Positives = 41/84 (48%)
 Frame = -3

Query: 952  QVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVVASSSYNMVIREDNQTNRLQEALNL 1011
            Q+ +  F+++DVGGQ   R  W   +     +IFVV  +            +R+ EA   
Sbjct: 2498 QLQECQFNVWDVGGQDKIRPLWRHYYTGTQGLIFVVDCAD----------RDRIDEARQE 2349

Query: 1012 FKSIWNNRWLRTISVILFLNKQDL 1035
               I N+R +R   +++F NKQDL
Sbjct: 2348 LHRIINDREMRDAIILIFANKQDL 2277
>18949
          Length = 414

 Score = 38.1 bits (87), Expect = 0.018,   Method: Composition-based stats.
 Identities = 24/79 (30%), Positives = 36/79 (45%)
 Frame = +3

Query: 956  VNFHMFDVGGQRDERRKWIQCFNDVTAIIFVVASSSYNMVIREDNQTNRLQEALNLFKSI 1015
            + F  FD+GG R  RR W   F  V  I+F+V          + + T R+ EA     S+
Sbjct: 57   MTFTTFDLGGHRQARRVWKDYFPAVDGIVFIV----------DVHDTERITEAKAELDSL 206

Query: 1016 WNNRWLRTISVILFLNKQD 1034
              +  +  I V++  NK D
Sbjct: 207  LRDDQIADIPVLVLGNKMD 263
>11378
          Length = 1688

 Score = 33.1 bits (74), Expect = 0.70,   Method: Compositional matrix adjust.
 Identities = 14/32 (43%), Positives = 18/32 (56%)
 Frame = +3

Query: 956 VNFHMFDVGGQRDERRKWIQCFNDVTAIIFVV 987
           + F  FD+GG R  RR W   F  V  I+F+V
Sbjct: 453 MRFTTFDLGGHRQARRVWKDYFPAVDGIVFLV 548
>28331
          Length = 371

 Score = 30.0 bits (66), Expect = 5.0,   Method: Composition-based stats.
 Identities = 15/33 (45%), Positives = 18/33 (54%)
 Frame = -3

Query: 246 RVIPQIGIGGEFPTVAVPSALCLAPAENAPPLW 278
           R  P I I   FP +A+  AL   PAE+  PLW
Sbjct: 156 RPFPPIKISMSFPGMALAWALARVPAEHQSPLW 58
>18208
          Length = 458

 Score = 30.0 bits (66), Expect = 5.0,   Method: Composition-based stats.
 Identities = 15/48 (31%), Positives = 23/48 (47%)
 Frame = -1

Query: 943 TSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVVASS 990
           T G      Q      +++D+GGQR  R  W   F +   +I+V+ SS
Sbjct: 209 TQGFNIKSVQSKGFKLNVWDIGGQRRIRPYWKNYFENTDLLIYVIDSS 66
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|30794206|ref|NP_084385.1| splicing factor 3b, subunit
2 [Mus musculus]
         (878 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

38446                                                                 209   5e-54
18874                                                                  30   5.9  
>38446
          Length = 1526

 Score =  209 bits (531), Expect = 5e-54,   Method: Compositional matrix adjust.
 Identities = 124/255 (48%), Positives = 148/255 (58%), Gaps = 4/255 (1%)
 Frame = -3

Query: 628  YPNLKIPGLNSPIPESCSFGYHAGGWGKPPVDETGKPLYGDVFGTNAAEFQTKTEEEEID 687
            YP  KIPGLN+PIPE CSFGYHAGGWGKPPVDE GKPLYGDVFGT   +     EEEEID
Sbjct: 1524 YPTSKIPGLNAPIPEGCSFGYHAGGWGKPPVDEMGKPLYGDVFGTKGGDATEADEEEEID 1345

Query: 688  RTPWGXXXXXXXXXXXXXXXXXXXXXXXXXTGFITPADSGLITPGGFSSVPAGMETPXXX 747
            ++ WG                         +G +TPA+ GL+TP G +S+P G+ETP   
Sbjct: 1344 KSHWG----EMESESESEEESEEEEEEKDESGLVTPAE-GLVTPSGLTSIPVGVETPDMI 1180

Query: 748  XXXXXXXXXAMD-GSETPQLFTVLPENRTATVGGAMMGSTHIYDMSTVMSRKGPAPE--- 803
                     AMD G +TP L+TVLPE +TA VGGAMMGS+HIYDM+ V   K  A +   
Sbjct: 1179 ELRKRRIEDAMDQGGDTPALYTVLPEKKTA-VGGAMMGSSHIYDMAGVQPGKKGAEKGGT 1003

Query: 804  LQGXXXXXXXXXXXXDPMAMTQKYEEHVREQQAQVEKEDFSDMVAEHXXXXXXXXXXXXP 863
             +G            D  AM  KY+E +REQQ+Q+EKED SDMVA H             
Sbjct: 1002 AEGVEVTLNPEELDLDTAAMQAKYDETMREQQSQIEKEDLSDMVAAHAAKQRKRKKQQA- 826

Query: 864  QDSRGGSKKYKEFKF 878
             DS   SK+YK+FKF
Sbjct: 825  -DSGKTSKRYKDFKF 784
>18874
          Length = 1177

 Score = 29.6 bits (65), Expect = 5.9,   Method: Compositional matrix adjust.
 Identities = 18/74 (24%), Positives = 33/74 (44%)
 Frame = -2

Query: 485  RHWCFKRKYLQGKRGIEKPPFELPDFIKRTGIQEMREALQEKEEQKTMKSKMREKVRPKM 544
            R W     +  G R    PP   P    +   + +  AL+  +E  ++KS++ +  R ++
Sbjct: 1137 RRWPSTPPWCTGWRVDASPPIPFPPLSYKHDTKLLILALERLKEAYSVKSRLNQSQREEL 958

Query: 545  GKIDIDYQKLHDAF 558
            G I+  Y   H+A 
Sbjct: 957  GLIEQAYDNPHEAL 916
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|90903233|ref|NP_001032830.2| glutathione peroxidase 4
isoform 1 precursor [Mus musculus]
         (253 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

02383                                                                 206   6e-54
27532                                                                 134   4e-32
33132                                                                  46   1e-05
04379                                                                  29   1.7  
>02383
          Length = 2075

 Score =  206 bits (525), Expect = 6e-54,   Method: Compositional matrix adjust.
 Identities = 104/174 (59%), Positives = 130/174 (74%), Gaps = 2/174 (1%)
 Frame = -1

Query: 78   SSEFLGLCASRDDWRCARSMHEFSAKDIDGHMVCLDKYRGFVCIVTNVASQUGKTDVNYT 137
            S+  +   A+ ++W+ A S++EFSAKDIDG+ V LDKY+G VC++ NVAS+ G TD NY 
Sbjct: 2075 SASTMASGANGEEWKTAGSIYEFSAKDIDGNEVSLDKYKGHVCLIVNVASK*GFTDKNYX 1896

Query: 138  QLVDLHARYAEC-GLRILAFPCNQFGRQEPGSNQEIKEFA-AGYNVKFDMYSKICVNGDD 195
            QL +LH +YAE  GLRILAFPCNQFG QEP    EIKEFA + YNV+FDM+SKI VNGD 
Sbjct: 1895 QLQELHTKYAESKGLRILAFPCNQFGSQEPWPEPEIKEFAVSKYNVQFDMFSKINVNGDG 1716

Query: 196  AHPLWKWMKVQPKGRGMLGNAIKWNFTKFLIDKNGCVVKRYGPMEEPQVIEKDL 249
            AHPL+K++K   K +G LG+ IKWNF+KFL+DKNG  VKRY P  EP    KD+
Sbjct: 1715 AHPLFKYLK--KKQKGTLGDFIKWNFSKFLVDKNGQPVKRYSPKTEPNATLKDM 1560
>27532
          Length = 483

 Score =  134 bits (336), Expect = 4e-32,   Method: Compositional matrix adjust.
 Identities = 69/126 (54%), Positives = 89/126 (70%), Gaps = 2/126 (1%)
 Frame = +2

Query: 130 GKTDVNYTQLVDLHARYAEC-GLRILAFPCNQFGRQEPGSNQEIKEFAA-GYNVKFDMYS 187
           GKT+ +Y+QL+ LH R+A+  GLRILAFPCNQF +QEP ++ EIKEF    Y V+FD++S
Sbjct: 5   GKTERDYSQLMALHRRHADTRGLRILAFPCNQFKQQEPWTDDEIKEFVTRKYKVEFDLFS 184

Query: 188 KICVNGDDAHPLWKWMKVQPKGRGMLGNAIKWNFTKFLIDKNGCVVKRYGPMEEPQVIEK 247
           K+ VNGDDA PL+KW+K +  G    G  I+WNF  F+IDK G  VKRY P   PQ +E+
Sbjct: 185 KVKVNGDDALPLYKWLKSRLPGEK--GEDIEWNFAXFVIDKTGQPVKRYAPXVPPQDMEQ 358

Query: 248 DLPCYL 253
           DL   L
Sbjct: 359 DLLSLL 376
>33132
          Length = 368

 Score = 46.2 bits (108), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 27/85 (31%), Positives = 40/85 (47%), Gaps = 12/85 (14%)
 Frame = +2

Query: 177 AGYNVKFDMYSKICVNGDDAHPLWKWMKVQ-PKGRGML-----------GNAIKWNFTKF 224
            G+   F M++KI VNGD  HPL+ ++K   P                  + + WN+  F
Sbjct: 2   GGFVPNFQMFAKIDVNGDTEHPLYTYLKKYCPPTTDTFHDPVLMYTPIKSSDVAWNWETF 181

Query: 225 LIDKNGCVVKRYGPMEEPQVIEKDL 249
           LI++ G VV R  P  +PQ  E  +
Sbjct: 182 LINRQGKVVARAPPALDPQAWESAI 256
>04379
          Length = 1012

 Score = 29.3 bits (64), Expect = 1.7,   Method: Compositional matrix adjust.
 Identities = 12/25 (48%), Positives = 16/25 (64%)
 Frame = +3

Query: 95  RSMHEFSAKDIDGHMVCLDKYRGFV 119
           RS H+FSA  I+GH+ C     GF+
Sbjct: 678 RSFHQFSAFIINGHVSCFQHAVGFM 752
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|111154082|ref|NP_598594.2| dystonin isoform a [Mus
musculus]
         (5379 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

19002                                                                 211   9e-54
02929                                                                 196   2e-49
19147                                                                 103   1e-21
29446                                                                  99   5e-20
17613                                                                  64   1e-17
09711                                                                  72   8e-12
34417                                                                  62   5e-09
23752                                                                  61   1e-08
05733                                                                  61   1e-08
19912                                                                  55   5e-07
32088                                                                  55   8e-07
04951                                                                  49   4e-05
32371                                                                  31   3e-04
09100                                                                  44   0.002
18202                                                                  43   0.003
25483                                                                  39   0.075
17484                                                                  37   0.15 
18556                                                                  37   0.18 
26019                                                                  36   0.38 
17977                                                                  35   1.1  
26849                                                                  35   1.1  
38533                                                                  34   1.2  
07678                                                                  33   2.2  
>19002
          Length = 842

 Score =  211 bits (536), Expect = 9e-54,   Method: Compositional matrix adjust.
 Identities = 121/264 (45%), Positives = 162/264 (61%), Gaps = 15/264 (5%)
 Frame = -2

Query: 65  DGHNLISLLEV-LSGDTLPREKGRMRFHRLQNVQIALDYLKRRQVKLVNIRNDDITDGNP 123
           DG  L+ LLEV + G+     KG+MR H L+NV  AL +L  ++V L N+   DI DG+ 
Sbjct: 841 DGKMLMKLLEVRVRGEIASDXKGKMRIHCLENVDKALTFLHEQRVHLENMGAHDIVDGSS 662

Query: 124 KLTLGLIWTIILHFQISDIHV--TGESEDMSAKERLLLWTQQATEGYAGVRCENFTTCWR 181
           +LTLGLIWTIIL FQI DI +     SE  SAK+ LLLW Q  T GY  V   NFTT WR
Sbjct: 661 RLTLGLIWTIILRFQIQDIMIEEVDNSETKSAKDALLLWCQMKTAGYPNVNVRNFTTSWR 482

Query: 182 DGKLFNAIIHKYRPDLIDMNTVAVQSNLANLEHAFYVAE-KIGVIRLLDPEDVDVSSPDE 240
           DG  FNAIIHK+RPDL+  + +   S + NL++AF VAE K+G+  LL+PEDV+V  PDE
Sbjct: 481 DGLAFNAIIHKHRPDLVQYDRLHKSSAIQNLQNAFTVAEDKLGLTALLEPEDVNVEYPDE 302

Query: 241 KSVITYVSSLYDAFPKVPEG---GEGIG-----ANDVEVKWIEYQNMVNYLIQWIRHHVV 292
           KS+ITYV + Y  F K+      G+ IG     A + E    EY+ + + L++WI   +V
Sbjct: 301 KSIITYVVTYYHYFSKMKADSVQGKRIGKVIDNAINTENSIEEYETLTSDLLEWIEQTIV 122

Query: 293 TMSERTFPNNPLELK---ALYNQY 313
            + +R F N+   ++   A +N Y
Sbjct: 121 ILRDRQFANSLTGVQQQLAAFNTY 50
>02929
          Length = 1353

 Score =  196 bits (498), Expect = 2e-49,   Method: Composition-based stats.
 Identities = 94/218 (43%), Positives = 145/218 (66%), Gaps = 2/218 (0%)
 Frame = +2

Query: 4966 LALERRRKLNDALDRLEELREFANFDFDIWRKKYMRWMNHKKSRVMDFFRRIDKDQDGKI 5025
            +A+ER++ L DA + L+EL  F NFDF+ WR KY++W+  KK RV DFFRR DKD DG +
Sbjct: 50   MAVERKKALQDAYEMLQELENFKNFDFESWRGKYLKWIQAKKFRVTDFFRRQDKDGDGFL 229

Query: 5026 TRQEFIDGILSSKFPTSRLEMSAVADIFDRDGDGYIDYYEFVAALHPNK--DAYKPITDA 5083
            T +EF++G++ S+FPT+R E++AV DIFDR+  G I+Y +FV AL P+K   + + ++D 
Sbjct: 230  TEEEFVNGMMQSRFPTNRTELNAVFDIFDREKRGLIEYKDFVDALKPDKFRTSSRAMSDD 409

Query: 5084 DKIEDEVTRQVAKCKCAKRFQVEQIGDNKYRFFLGNQFGDSQQLRLVRILRSTVMVRVGG 5143
            + I+D + ++   C C ++F   ++   KYR      FG+ Q++ LVR+L  +VMVRVGG
Sbjct: 410  EVIQDSIDQEANGCSCREQFTGYRVDKGKYR------FGEKQKIVLVRLLNKSVMVRVGG 571

Query: 5144 GWMALDEFLVKNDPCRVHHHGSKMLRSESNSSITATQP 5181
            GW+ L+EF + NDPC+     S    S+  ++ ++  P
Sbjct: 572  GWVPLEEFFLTNDPCKAKGRSSFDHVSDGQTAHSSISP 685
>19147
          Length = 474

 Score =  103 bits (258), Expect = 1e-21,   Method: Compositional matrix adjust.
 Identities = 50/103 (48%), Positives = 72/103 (69%)
 Frame = +1

Query: 102 YLKRRQVKLVNIRNDDITDGNPKLTLGLIWTIILHFQISDIHVTGESEDMSAKERLLLWT 161
           Y+  + VKLV+I  ++I DGN K+TLG+IWTIIL F I DI V    E+++AKE LLLW 
Sbjct: 49  YIASKGVKLVSIGAEEIVDGNVKMTLGMIWTIILRFAIQDITV----EELTAKEGLLLWC 216

Query: 162 QQATEGYAGVRCENFTTCWRDGKLFNAIIHKYRPDLIDMNTVA 204
           Q+ T  Y  V  +NF   ++DG  F A+IH++RP+LID ++++
Sbjct: 217 QRKTAPYKNVNVQNFHLSFKDGLAFCALIHRHRPELIDYHSLS 345
>29446
          Length = 1445

 Score = 98.6 bits (244), Expect = 5e-20,   Method: Compositional matrix adjust.
 Identities = 58/135 (42%), Positives = 78/135 (57%), Gaps = 8/135 (5%)
 Frame = +3

Query: 36   VQKKTFTKWINQHLMKVRKHVNDLYEDLRDGHNLISLLEVLSGDTLPREKGRMRF--HRL 93
            +QK TFT+W N+HL  V K + DL  D  DG  L++L+EVLSG        R  F   +L
Sbjct: 999  IQKNTFTRWANEHLRTVNKAIADLESDFSDGLRLVALIEVLSGKKFKHVNKRPNFRTQKL 1178

Query: 94   QNVQIALDYLKRRQ-VKLVNIRNDDITDGNPKLTLGLIWTIILHFQISDIHVTGESEDMS 152
            +NV + L +L+  + +++VNI + DI D   KL LGLIWT+ILH+ IS     GE    S
Sbjct: 1179 ENVTLTLKFLEDDEGIRIVNIDSTDIVDKKLKLILGLIWTLILHYSISMPMWEGEEPTPS 1358

Query: 153  -----AKERLLLWTQ 162
                  K+RLL W Q
Sbjct: 1359 EGGPTPKQRLLNWIQ 1403
>17613
          Length = 1108

 Score = 64.3 bits (155), Expect(2) = 1e-17,   Method: Composition-based stats.
 Identities = 33/58 (56%), Positives = 43/58 (74%)
 Frame = +2

Query: 106 RQVKLVNIRNDDITDGNPKLTLGLIWTIILHFQISDIHVTGESEDMSAKERLLLWTQQ 163
           + VKLV+I  ++I DGN K+TLG+IWTIIL F I DI V    E+++AKE LLLW Q+
Sbjct: 59  KGVKLVSIGAEEIVDGNVKMTLGMIWTIILRFAIQDITV----EELTAKEGLLLWCQR 220

 Score = 47.0 bits (110), Expect(2) = 1e-17,   Method: Compositional matrix adjust.
 Identities = 35/101 (34%), Positives = 53/101 (52%), Gaps = 14/101 (13%)
 Frame = +3

Query: 202 TVAVQSNLANLEHAF-YVAEKIGVIRLLDPED-VDVSSPDEKSVITYVSSLYDAFPKVPE 259
           TV  QS +   +H F +  + + + R+LDPED V+ + PDE+SV+ YVSS Y AF     
Sbjct: 336 TVKGQS-IGEPQHCF*HRRKHLDIPRMLDPEDMVNSAKPDERSVMAYVSSYYHAF----S 500

Query: 260 GGEG--IGANDV----------EVKWIEYQNMVNYLIQWIR 288
           G +     AN +          E    EY+ + + L++WIR
Sbjct: 501 GAQQAETAANRICKVLKVNQENERLMEEYERLASDLLEWIR 623

 Score = 62.0 bits (149), Expect = 6e-09,   Method: Composition-based stats.
 Identities = 46/145 (31%), Positives = 67/145 (46%), Gaps = 12/145 (8%)
 Frame = +1

Query: 88  MRFHRLQNVQIALDY--LKRRQVKLVNIR-------NDDIT---DGNPKLTLGLIWTIIL 135
           MRFH++ NV  ALDY  L+R Q  L   R        DDI    D  P++          
Sbjct: 4   MRFHKIANVNKALDYIDLQRGQTGLHRSRRNC*RQRKDDIRYDLDNYPQVC--------- 156

Query: 136 HFQISDIHVTGESEDMSAKERLLLWTQQATEGYAGVRCENFTTCWRDGKLFNAIIHKYRP 195
                  H    S     + R ++     T  Y  V  +NF   ++DG  F A+IH++RP
Sbjct: 157 -------HPRHHSRRTHCQRRTVIVVPAKTAPYKNVNVQNFHLSFKDGLAFCALIHRHRP 315

Query: 196 DLIDMNTVAVQSNLANLEHAFYVAE 220
           +LID ++++  + L NL  AF +AE
Sbjct: 316 ELIDYHSLSKDNPLENLNTAFDIAE 390
>09711
          Length = 3041

 Score = 71.6 bits (174), Expect = 8e-12,   Method: Compositional matrix adjust.
 Identities = 60/232 (25%), Positives = 104/232 (44%), Gaps = 18/232 (7%)
 Frame = +1

Query: 37   QKKTFTKWINQHLMKVRKHVNDLYEDLRDGHNLISLLEVL-------SGDTLPREKGRMR 89
            ++KT+  W+N   + V   V+ LY DL DG  +  L + +       S       K + R
Sbjct: 850  EEKTYRNWMNS--LGVSPFVHHLYSDLYDGLIIFQLYDYIQPGLVDWSKVKKKFNKLKAR 1023

Query: 90   FHRLQNVQIALDY---LKRRQVKLVNIRNDDITDGNPKLTLGLIWTIILHFQISDIHVTG 146
            F R++N   A++    +K  +VKLV I   DI DGNP LTLGL+W ++  + ++ +    
Sbjct: 1024 FERIENCNYAVELGPQVKLVKVKLVGIAGQDILDGNPVLTLGLVWQLMRAYTLAILSKIT 1203

Query: 147  ESEDMSAKERLLLWTQQAT---EGYAGVRCENFTTCWRDGKLFNAIIHKYRPDLIDMNTV 203
            E+    +   ++ W        +  +G +         DG +   +I   +P +++ + +
Sbjct: 1204 ENNKPISDNEIITWVNSKIKKDDRISGFQDRKLN----DGVIVARVIEAIKPGIVNWDNI 1371

Query: 204  AV-----QSNLANLEHAFYVAEKIGVIRLLDPEDVDVSSPDEKSVITYVSSL 250
                   Q  L N  +A  +A KIG      PED+    P  K ++T  + L
Sbjct: 1372 DCSARDYQDRLTNARYAIGLARKIGAGVYALPEDIVEVKP--KMLLTVFACL 1521

 Score = 51.2 bits (121), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 61/253 (24%), Positives = 113/253 (44%), Gaps = 32/253 (12%)
 Frame = +1

Query: 37  QKKTFTKWINQHLMKVR--KHV-------NDLYEDLRDGHNLISLLEVLSGDTLP----R 83
           ++K F +WIN+HL      KH+         L+  + DG  L  L+     +T+      
Sbjct: 52  EQKAFAEWINRHLSDXPDCKHLLPLDADGTQLFGQMADGVLLCKLINHSVSNTIDERTIN 231

Query: 84  EKGRMRFHRLQNVQIALDYLKRRQVKLVNIRNDDITDGNPKLTLGLIWTIILHFQISDIH 143
           ++    + R +N+ +A++         VNI  +D+  G P L LGL+W II    +SDI+
Sbjct: 232 KQNLSLYRRHENLTLAVNSAGAIGCTTVNIGPEDLAAGRPHLVLGLLWQIIRIGLLSDIN 411

Query: 144 VT-----------GES-ED---MSAKERLLLWTQQATEGYAGV--RCENFTTCWRDGKLF 186
           +            GE+ ED   +S ++ LL W        AG   +  NF    +D + +
Sbjct: 412 LAHHPGLVNLLLDGETIEDLIRLSPEQILLRWVNYHLN-RAGCDRQIXNFGEDIKDSEAY 588

Query: 187 NAIIHKYRPDL--IDMNTVAVQSNLANLEHAFYVAEKIGVIRLLDPEDVDVSSPDEKSVI 244
             ++ +  P    + ++ ++V       E     A+KIG    +     DV S ++K  +
Sbjct: 589 THLLKQISPPSAGVTLSPLSVGDVHQRAECMLQEADKIGCRSFVGAS--DVVSGNQKLNL 762

Query: 245 TYVSSLYDAFPKV 257
            +V++L++ +P +
Sbjct: 763 AFVANLFNNYPAL 801
>34417
          Length = 1096

 Score = 62.4 bits (150), Expect = 5e-09,   Method: Composition-based stats.
 Identities = 34/82 (41%), Positives = 47/82 (57%), Gaps = 2/82 (2%)
 Frame = +2

Query: 172 RCENFTTCWRDGKLFNAIIHKYRPDLIDMNTVAVQSNLANLEHAFYVAEKIGVIR-LLDP 230
           R +  ++CW +G  F A+IH + PD  D + +  Q+   N E AF  AEK+  I  LLD 
Sbjct: 23  RGDQLSSCWNNGLAFCALIHHFYPDAFDYSQLQPQNRRYNFELAFDTAEKLADISPLLDV 202

Query: 231 ED-VDVSSPDEKSVITYVSSLY 251
           ED + + +PD K V TYV S Y
Sbjct: 203 EDMIKMKNPDWKCVFTYVQSFY 268
>23752
          Length = 853

 Score = 61.2 bits (147), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 38/128 (29%), Positives = 69/128 (53%), Gaps = 6/128 (4%)
 Frame = -2

Query: 782 AMQTQWSWILQLCQCVEQHIQENSAYFEFFNDAKEATDYLRNLKDAIQRKYSCDRS---- 837
           A+++ W W+ Q+ QC E H++  +AY EFF++ +EA  ++ N    I   +  DR+    
Sbjct: 366 AVRSNWQWMSQVMQCAEVHLRNAAAYHEFFHEVEEAEYWMENTLSRIHMSF--DRNKLQG 193

Query: 838 --SSIHKLEDLVQESMEKEELLQYRSVVAGLMGRAKTVVQLKPRNPDNPLKTSIPIKAIC 895
             + +  ++D ++E +     LQ+++ +  L  RAKTVV +  R     LK   P+ A+ 
Sbjct: 192 NRTDVVAIQDEIKEVLAG--FLQWQTKIDYLFDRAKTVVPVPQRT--TALKEERPVIALT 25

Query: 896 DYRQIEIT 903
           D+   +IT
Sbjct: 24  DFSNSQIT 1
>05733
          Length = 1021

 Score = 60.8 bits (146), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 34/102 (33%), Positives = 57/102 (55%), Gaps = 4/102 (3%)
 Frame = +2

Query: 157 LLLWTQQATEG--YAGVRCENFTTCWRDGKLFNAIIHKYRPDLIDMNTVAVQSNLANLEH 214
           LL W Q+      Y GV   +FT+ WR G  F A+IH +RP LI   ++     + N + 
Sbjct: 470 LLRWCQRVLNXGTYRGVHIIDFTSSWRSGLAFCALIHAFRPHLISPASLMECETVKNNQL 649

Query: 215 AFYVAEK-IGVIRLLDPEDVDVSS-PDEKSVITYVSSLYDAF 254
           AF VA+K +G+  ++  ED+   + PD+ +++ Y+S  ++ F
Sbjct: 650 AFDVAQKELGIAPVMRGEDMAACAVPDKLTMVAYLSQFHELF 775
>19912
          Length = 865

 Score = 55.5 bits (132), Expect = 5e-07,   Method: Composition-based stats.
 Identities = 26/70 (37%), Positives = 40/70 (57%)
 Frame = +2

Query: 4998 KYMRWMNHKKSRVMDFFRRIDKDQDGKITRQEFIDGILSSKFPTSRLEMSAVADIFDRDG 5057
            K M +++    R++DFF + DK+    ITR +F  G+  +  P +  E+  + D  DRDG
Sbjct: 638  KLMAYIDSNNLRLVDFFNKFDKEGTMSITRDQFRQGLTEASIPLAGDEVDFLLDELDRDG 817

Query: 5058 DGYIDYYEFV 5067
            DG I+Y E V
Sbjct: 818  DGEINYSELV 847
>32088
          Length = 1928

 Score = 55.1 bits (131), Expect = 8e-07,   Method: Composition-based stats.
 Identities = 47/158 (29%), Positives = 75/158 (47%), Gaps = 28/158 (17%)
 Frame = +1

Query: 37   QKKTFTKWIN---------QHLMKVRKHVNDLYEDLRDGHNLISLLEVLSGDTLPRE--- 84
            ++K F  WIN         +HLM+V +  +DL++ + DG  L  L+     +T+      
Sbjct: 1264 EQKAFAAWINRHLKDDPDCKHLMEVNEEGDDLFKKVGDGILLCKLINHSVSNTIDERAIN 1443

Query: 85   KGRMR-FHRLQNVQIALDYLKRRQVKLVNIRNDDITDGNPKLTLGLIWTIILHFQISDIH 143
            K  +  +HR +N+ +A++         VNI  +D+  G P L LGL+W II    +SDI+
Sbjct: 1444 KSNLNVYHRHENLTLAVNSAGSIGCTTVNIGPEDLAAGRPHLVLGLLWQIIRIGLLSDIN 1623

Query: 144  VT-----------GES-ED---MSAKERLLLWTQQATE 166
            +            GE+ ED   +S +E LL W     E
Sbjct: 1624 LAHHPGLVNLLREGETIEDFMRLSPEEILLRWVNYHLE 1737
>04951
          Length = 2852

 Score = 49.3 bits (116), Expect = 4e-05,   Method: Composition-based stats.
 Identities = 40/151 (26%), Positives = 69/151 (45%), Gaps = 9/151 (5%)
 Frame = +1

Query: 92  RLQNVQIALDY---LKRRQVKLVNIRNDDITDGNPKLTLGLIWTIILHFQISDIHVTGES 148
           +++N + A+     +K  ++KLV I   DI DGNP LTLGL+W ++  + ++ +    E 
Sbjct: 4   KIENCEYAVQLGPQMKVCKMKLVGIGGKDIHDGNPVLTLGLVWQLMRAYTLAILSKLTED 183

Query: 149 EDMSAKERLLLWTQQATEGYAGVRCENFT-TCWRDGKLFNAIIHKYRPDL-----IDMNT 202
           +       ++ W     +     R  +F  +   DG +   +I   +P +     I+ N 
Sbjct: 184 KKPIQDSEIVDWVNSKVK--KDERIGSFQDSKLNDGVIVAKVIESIKPGIVNWENINPNA 357

Query: 203 VAVQSNLANLEHAFYVAEKIGVIRLLDPEDV 233
                 LAN  +A  +A KIG      PED+
Sbjct: 358 SEPDDRLANARYAIGLARKIGAGVYALPEDI 450
>32371
          Length = 625

 Score = 30.8 bits (68), Expect(3) = 3e-04,   Method: Composition-based stats.
 Identities = 14/28 (50%), Positives = 18/28 (64%), Gaps = 1/28 (3%)
 Frame = -3

Query: 242 SVITYVSSLYDAFPKVPE-GGEGIGAND 268
           SVITYVS  Y+    +P+ GG G+  ND
Sbjct: 401 SVITYVSQYYNKLSTLPQLGGPGVQGND 318

 Score = 26.9 bits (58), Expect(3) = 3e-04,   Method: Composition-based stats.
 Identities = 10/24 (41%), Positives = 15/24 (62%)
 Frame = -1

Query: 171 VRCENFTTCWRDGKLFNAIIHKYR 194
           V  ++    WR+G  F AIIH++R
Sbjct: 622 VDIKDLLVSWRNGLAFCAIIHRFR 551

 Score = 26.2 bits (56), Expect(3) = 3e-04,   Method: Compositional matrix adjust.
 Identities = 17/48 (35%), Positives = 30/48 (62%), Gaps = 2/48 (4%)
 Frame = -2

Query: 195 PDLIDMNTVAVQSNLANLEHAFYVAEK-IGVIRLLDPED-VDVSSPDE 240
           PDLID ++++ ++ L N   AF VAE+ + +   L+  D V + +PD+
Sbjct: 549 PDLIDYDSLSKENVLYNNNLAFTVAEQELDIPAFLEAADMVALRTPDK 406
>09100
          Length = 930

 Score = 43.5 bits (101), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 31/110 (28%), Positives = 52/110 (47%), Gaps = 8/110 (7%)
 Frame = +1

Query: 37  QKKTFTKWINQHLMK-VRKH-VNDLYEDLRDGHNLISLLEVLSGDTLPREKG------RM 88
           Q   +  WIN  L K    H + DL  D+RDG     ++ ++S   +P  +        M
Sbjct: 463 QLSAYMAWINSQLKKKPGAHLIEDLRHDMRDGVVFADVIHIVSKQQIPGIQNVPTTLDEM 642

Query: 89  RFHRLQNVQIALDYLKRRQVKLVNIRNDDITDGNPKLTLGLIWTIILHFQ 138
           R    QNV   L ++ + ++K+  I + DI +GN K  + LI  +  H++
Sbjct: 643 R----QNVDRVLHFMTQNRIKMHRISSRDIVEGNLKAVMRLILALAAHYK 780
>18202
          Length = 424

 Score = 43.1 bits (100), Expect = 0.003,   Method: Composition-based stats.
 Identities = 34/127 (26%), Positives = 63/127 (49%), Gaps = 3/127 (2%)
 Frame = -1

Query: 39  KTFTKWINQHLMKVRKHVNDLYEDLRDGHNLISLLEVLSGDT--LPREKGRMRFHRLQNV 96
           + +  W N  L +V   V ++   +++G  L  L++VL+ +   L + +   +  +   +
Sbjct: 385 QVYLSWANSVLCEVNSSVENV-SSIQEGRVLCELIDVLAPEAGLLDKVQASGKSGQRAFI 209

Query: 97  QIALDYLKRRQVKLVNIRNDDITDGNPKLTLGLIWTIILHFQISDIHVTGESEDMSA-KE 155
             ALD++K   +K+V     DI DG+ K  L ++W +IL++ I  I        + A K+
Sbjct: 208 YAALDHMKNHGIKIV-FSTQDIMDGDIKSLLDVMWLLILNYGIHFIGNNSFQRSVGAGKK 32

Query: 156 RLLLWTQ 162
            LL W Q
Sbjct: 31  NLLDWCQ 11
>25483
          Length = 438

 Score = 38.5 bits (88), Expect = 0.075,   Method: Compositional matrix adjust.
 Identities = 28/112 (25%), Positives = 54/112 (48%), Gaps = 5/112 (4%)
 Frame = -2

Query: 3284 DSVNSRWKTLNKKVAQR---TSQLQEALLHCGRFQDALESLLSWMADTEELVANQKPPSA 3340
            DS+N RWK L  +V +R     +++E       F D ++ L  W+ +TE ++A+      
Sbjct: 335  DSINQRWKALCSEVFERQKYAGRVEEGSTRTSDFTDDMDELFFWIDETENILAS--TLKL 162

Query: 3341 EFKVVKAQIQEQKLLQRLLEDRKSTVEVIKREGEK--IAASAEPADRVKLTR 3390
            E + +   +++ K  Q  +  R+  +  I+  G +  ++ S  P DR  + R
Sbjct: 161  ETQYLSDLLEKVKDRQEDVASRQQNLTAIQTNGTRLVLSDSMTPEDRTNIQR 6

 Score = 37.4 bits (85), Expect = 0.17,   Method: Compositional matrix adjust.
 Identities = 22/89 (24%), Positives = 50/89 (56%), Gaps = 3/89 (3%)
 Frame = -2

Query: 4235 VLAHQSTVEAVNKAGNDLIESSEGEEASNLQYKLRILNQRWQDILEKTDQRKQ---QLDS 4291
            +   Q TV ++N AGN+++      +A  L+ +   +NQRW+ +  +  +R++   +++ 
Sbjct: 437  IRVEQGTVNSMNSAGNEMLRQMSAPQADLLRQRQDSINQRWKALCSEVFERQKYAGRVEE 258

Query: 4292 ALRQAKGFHGEIEDLQQWLTDTERHLLAS 4320
               +   F  ++++L  W+ +TE ++LAS
Sbjct: 257  GSTRTSDFTDDMDELFFWIDETE-NILAS 174
>17484
          Length = 471

 Score = 37.4 bits (85), Expect = 0.15,   Method: Composition-based stats.
 Identities = 19/67 (28%), Positives = 34/67 (50%)
 Frame = -3

Query: 5000 MRWMNHKKSRVMDFFRRIDKDQDGKITRQEFIDGILSSKFPTSRLEMSAVADIFDRDGDG 5059
            M+  + K   + D FR  D++ DG I+  E    +       S  ++ ++    D+DGDG
Sbjct: 295  MKGGSEKDKEMRDAFRAFDQNGDGVISISELRQAMAKMGQKLSDADVESIIRDVDKDGDG 116

Query: 5060 YIDYYEF 5066
            +++Y EF
Sbjct: 115  FVNYEEF 95
>18556
          Length = 799

 Score = 37.4 bits (85), Expect = 0.18,   Method: Compositional matrix adjust.
 Identities = 21/77 (27%), Positives = 43/77 (55%), Gaps = 2/77 (2%)
 Frame = +2

Query: 180 WRDGKLFNAIIHKYRPDLIDMNTVAVQSNLANLEHAFYVAEK-IGVIRLLDP-EDVDVSS 237
           +R+G++  A+I ++RPDLID       S L   E AF V E+ + + R++   + +D++ 
Sbjct: 119 FRNGRVLCALISRFRPDLIDYAATKDMSPLECNELAFAVLERELHIDRIMSAKQSLDLND 298

Query: 238 PDEKSVITYVSSLYDAF 254
            + +  + Y+  + + F
Sbjct: 299 VESRVWLNYMDQICELF 349
>26019
          Length = 1561

 Score = 36.2 bits (82), Expect = 0.38,   Method: Composition-based stats.
 Identities = 20/62 (32%), Positives = 33/62 (53%)
 Frame = +2

Query: 5009 RVMDFFRRIDKDQDGKITRQEFIDGILSSKFPTSRLEMSAVADIFDRDGDGYIDYYEFVA 5068
            R+   FR++D D  G ++  EF+      + P     +  V DIFD DG+G +D+ EF+ 
Sbjct: 101  RLGKRFRKLDLDNSGSLSIDEFMSLPELQQNPL----VQRVIDIFDTDGNGEVDFKEFIE 268

Query: 5069 AL 5070
             +
Sbjct: 269  GI 274
>17977
          Length = 445

 Score = 34.7 bits (78), Expect = 1.1,   Method: Composition-based stats.
 Identities = 22/76 (28%), Positives = 33/76 (43%)
 Frame = +3

Query: 4996 RKKYMRWMNHKKSRVMDFFRRIDKDQDGKITRQEFIDGILSSKFPTSRLEMSAVADIFDR 5055
            R++  ++  H    ++  FR  DKD  GKI   +  +       P     +  V D  D 
Sbjct: 183  RQQLKKFNYHSFPDLIRAFRFYDKDGKGKIDIDDLREACRKFDVPIDVWLLEQVFDYCDE 362

Query: 5056 DGDGYIDYYEFVAALH 5071
            + DG IDY EF   L+
Sbjct: 363  NRDGQIDYLEFANFLN 410
>26849
          Length = 649

 Score = 34.7 bits (78), Expect = 1.1,   Method: Composition-based stats.
 Identities = 18/54 (33%), Positives = 29/54 (53%)
 Frame = +2

Query: 5014 FRRIDKDQDGKITRQEFIDGILSSKFPTSRLEMSAVADIFDRDGDGYIDYYEFV 5067
            FR +DKD    ++ +EF  GIL      +  ++  +   FD DG+G I+  EF+
Sbjct: 185  FRVMDKDGSKVLSLEEFKKGILDMHIDINEADIEDMFYRFDNDGNGTINMTEFL 346
>38533
          Length = 380

 Score = 34.3 bits (77), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 25/122 (20%), Positives = 56/122 (45%), Gaps = 7/122 (5%)
 Frame = +1

Query: 4198 LAWLTHTKGLLSEQKPVGGDPKAIEIELAKHHVLQNDVLAHQSTVEAVNKAGNDLIESSE 4257
            L+W    +  ++E   +G    A++  + KH  L+++++AH+  ++AV  +   +I +  
Sbjct: 13   LSWYY*DRKPIAESTDLGNSLTAVQNLMKKHQALESEIVAHEPLIDAVATSAQQMIRTKH 192

Query: 4258 GEEASNLQYKLRILNQRWQDILEKTDQRKQQL-------DSALRQAKGFHGEIEDLQQWL 4310
               A ++Q +L        D L    QR Q          +    A+ F+ E+ +++ W+
Sbjct: 193  FATA-DIQTRL--------DDLTSPAQRSQVFYLL*KVETAGCFGAQKFYMEVNEVELWM 345

Query: 4311 TD 4312
             +
Sbjct: 346  NE 351
>07678
          Length = 958

 Score = 33.5 bits (75), Expect = 2.2,   Method: Composition-based stats.
 Identities = 19/62 (30%), Positives = 34/62 (54%), Gaps = 3/62 (4%)
 Frame = +1

Query: 5014 FRRIDKDQDGKITRQEFIDGILSSKFPTSRLEMSAVADIF---DRDGDGYIDYYEFVAAL 5070
            F+ +D D +  +  +EF  GI  ++F  ++ E   + ++F   D+D  G ID+ EF+  L
Sbjct: 337  FKIMDDDGNRSLDFKEFKKGI--TEFGLTQFEGDVIQEMFTCFDKDZSGTIDFDEFLVKL 510

Query: 5071 HP 5072
             P
Sbjct: 511  RP 516
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|67906170|ref|NP_001013043.1| TGF beta receptor
associated protein -1 [Mus musculus]
         (860 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

25513                                                                 192   2e-53
19067                                                                  85   1e-16
26289                                                                  48   1e-05
13366                                                                  29   6.8  
>25513
          Length = 1246

 Score =  192 bits (488), Expect(2) = 2e-53,   Method: Compositional matrix adjust.
 Identities = 98/215 (45%), Positives = 137/215 (63%), Gaps = 1/215 (0%)
 Frame = -3

Query: 638  QAKLRRLLQKSDLYRVHLLKEKVQGAGLPMESAILHGKLGEHEKALHILVHEMGDFSAAE 697
            ++KLR +LQ S+LYRV L+  K +   +  E AIL+GKL EH+KAL ILVH++ DF AAE
Sbjct: 1121 RSKLRHMLQMSNLYRVQLILGKAKETDMHAECAILYGKLEEHDKALRILVHKLKDFGAAE 942

Query: 698  DYCLWSSEGQGAACRQRLFHTLLAMYLRAGPSAQD-LTVAAVDLLNHHAREFDVTQVLQL 756
            +YCL + + +  A R+RLFH LL++YL      +D L   AV LLN    EFD  +VLQL
Sbjct: 941  NYCLVNXQNKDPAYRKRLFHILLSVYLDPXYEKRDSLITPAVALLNSSVAEFDTIKVLQL 762

Query: 757  LPDTWSVQLLCPFLMGAMRDSIHARRTTQVALGLAKSENLIYMYDKMKLKGNAVRLSERE 816
            LPD WSV LL  FL  A+R S+H  R T++   +++ ENL     +++L+   V ++E  
Sbjct: 761  LPDNWSVGLLSQFLTRAVRSSMHDSRMTRIERMMSRVENLRCKETRIELQREPVVMNEER 582

Query: 817  LCQLCQNPFGEPVFVRYPNGGLVHTHCAASRHTAP 851
            LC +C+  F +P FV YPNG + H HCA ++   P
Sbjct: 581  LCAVCKRAFNDPTFVXYPNGVVTHVHCAKNKFICP 477

 Score = 36.2 bits (82), Expect(2) = 2e-53,   Method: Compositional matrix adjust.
 Identities = 15/21 (71%), Positives = 19/21 (90%)
 Frame = -1

Query: 602  RLQKEEYHTHLAILYLEEVLR 622
            +L+KE YHTHLA+LYL+ VLR
Sbjct: 1228 KLEKESYHTHLAVLYLDAVLR 1166
>19067
          Length = 567

 Score = 85.1 bits (209), Expect = 1e-16,   Method: Compositional matrix adjust.
 Identities = 55/189 (29%), Positives = 88/189 (46%), Gaps = 12/189 (6%)
 Frame = -2

Query: 675 KLGEHEKALHILVHEMGDFSAAEDYCLWSSEGQGAACRQRLFHTLLAMYLRA-------- 726
           +LG HE+AL I +H + D + AE YC    +      +  ++  LL MYL          
Sbjct: 566 RLGRHEQALAIYIHLLNDTALAEKYCEIHYDADKEESKD-VYLYLLKMYLHPPDMSLLGM 390

Query: 727 GPSAQDL----TVAAVDLLNHHAREFDVTQVLQLLPDTWSVQLLCPFLMGAMRDSIHARR 782
            P   D     T AA+ LL  HA + DV + L++LP T  V+ +  FL   + ++    R
Sbjct: 389 APGEHDSSKTNTNAALKLLEDHAHKIDVPKALEMLPSTIRVRDILTFLENVLENNAAEXR 210

Query: 783 TTQVALGLAKSENLIYMYDKMKLKGNAVRLSERELCQLCQNPFGEPVFVRYPNGGLVHTH 842
             QV   L  +ENL    ++++ +   V ++E  LC  C+   G+  F   P+G + H  
Sbjct: 209 HNQVLKSLTFAENLAVTEERIQYQKIRVDVTEDTLCPTCKKRIGDSAFCYTPDGSIYHYS 30

Query: 843 CAASRHTAP 851
           C   +  +P
Sbjct: 29  CYQHK*PSP 3
>26289
          Length = 476

 Score = 48.1 bits (113), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 30/98 (30%), Positives = 57/98 (58%), Gaps = 3/98 (3%)
 Frame = +1

Query: 526 YEYIVDFLTYCLDQ--ELVWTHADWLLQKSEEIGVQIFTKRPLDEQQQTSFNPDNIISSL 583
           +E  V +L +  ++  +L++ +A+W+L+K  E G++IFT+   D  +  +   D ++  L
Sbjct: 55  HERTVQYLQHLGNEHLDLIFEYAEWVLKKHPEDGLKIFTE---DTPEIETLPRDQVLDYL 225

Query: 584 KKYPKAL-VKYLEHLVIDRRLQKEEYHTHLAILYLEEV 620
           +K   AL + YLEH+V+D   +  E+H  L +L  + V
Sbjct: 226 EKIKPALAIPYLEHIVMDCGDETAEFHNRLVLLLKDSV 339
>13366
          Length = 1953

 Score = 29.3 bits (64), Expect = 6.8,   Method: Compositional matrix adjust.
 Identities = 18/55 (32%), Positives = 31/55 (56%), Gaps = 3/55 (5%)
 Frame = +1

Query: 212 IVKRIGRQEFLLAGPGGLGMFA---TVAGISQRAPVHWSENVIGAAVCFPYVIAL 263
           ++ ++GR+  ++AG GG+ +F    TVA + Q +    S   IGA V   Y++A 
Sbjct: 568 VIDKVGRRTLMIAGLGGMLIFTVVLTVALVFQNSATWLSFLCIGAVVL--YIVAF 726
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6680840|ref|NP_031620.1| calumenin isoform 1 [Mus
musculus]
         (315 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

11230                                                                 152   6e-53
15239                                                                 134   6e-32
07198                                                                 102   1e-31
08380                                                                 108   4e-24
15966                                                                  33   0.13 
01773                                                                  33   0.13 
14594                                                                  33   0.15 
07678                                                                  33   0.20 
17484                                                                  32   0.30 
14601                                                                  32   0.45 
00167                                                                  32   0.49 
39823                                                                  27   9.2  
>11230
          Length = 747

 Score =  152 bits (384), Expect(2) = 6e-53,   Method: Compositional matrix adjust.
 Identities = 76/118 (64%), Positives = 97/118 (82%), Gaps = 2/118 (1%)
 Frame = +3

Query: 200 IDKNADGFIDLEEYIGDMYSHDGNADE-PEWVKTEREQFVEFRDKNRDGKMDKEETKDWI 258
           IDK+ DG IDLEEYI DM+ +  N DE P+WVK+ER+QF  +RD ++DGK+D  E K WI
Sbjct: 267 IDKDKDGLIDLEEYIADMWPNRDNEDEEPDWVKSERKQFDTYRDLDKDGKLDPSEVKRWI 446

Query: 259 LPSDYDHAEAEARHLVYESD-QNKDGKLTKEEIVDKYDLFVGSQATDFGEALVRHDEF 315
           LP ++DHA AE++HL++E+D  +KDGKL+ +EI+DKYDLFVGSQATDFGEAL RHDEF
Sbjct: 447 LPENFDHARAESKHLIFEADGGDKDGKLSYDEILDKYDLFVGSQATDFGEALTRHDEF 620

 Score = 73.2 bits (178), Expect(2) = 6e-53,   Method: Compositional matrix adjust.
 Identities = 41/92 (44%), Positives = 58/92 (63%), Gaps = 2/92 (2%)
 Frame = +1

Query: 113 WKGHDLNEDGLVSWEEYKNATYGYVLDDPDPDDGFN--YKQMMVRDERRFKMADKDGDLI 170
           WK H  +ED  +SW  Y+  T+GY  DDP+        Y +M+ RD RR++ AD + D  
Sbjct: 4   WKDHIPDEDNHLSWVAYQKRTFGYE-DDPNTKGSRTEAYAEMINRDRRRWEKADHNKDNR 180

Query: 171 ATKEEFTAFLHPEEYDYMKDIVVQETMEDIDK 202
            +KEEF  FLHPE+ ++M+DIVV ET+E + K
Sbjct: 181 LSKEEFMDFLHPEDAEHMRDIVVMETVEALTK 276
>15239
          Length = 913

 Score =  134 bits (336), Expect = 6e-32,   Method: Compositional matrix adjust.
 Identities = 60/88 (68%), Positives = 77/88 (87%)
 Frame = +2

Query: 228 EWVKTEREQFVEFRDKNRDGKMDKEETKDWILPSDYDHAEAEARHLVYESDQNKDGKLTK 287
           +WV++ER+QF +FRDKN DGK+D  E ++WI+P DYDH+ AEA+HL+ +SD +KDGKL+ 
Sbjct: 2   DWVRSERDQFQQFRDKNNDGKLDANEVREWIIPDDYDHSSAEAKHLIGDSDGDKDGKLSY 181

Query: 288 EEIVDKYDLFVGSQATDFGEALVRHDEF 315
           +EI+DKYDLFVGSQATDFGEAL RHDEF
Sbjct: 182 DEILDKYDLFVGSQATDFGEALTRHDEF 265
>07198
          Length = 1675

 Score =  102 bits (254), Expect(2) = 1e-31,   Method: Compositional matrix adjust.
 Identities = 69/210 (32%), Positives = 108/210 (51%), Gaps = 16/210 (7%)
 Frame = -3

Query: 121 DGLVSWEEYKNATYGYVLDDPDP----------------DDGFNYKQMMVRDERRFKMAD 164
           DG V+W+EY +  YG+   D D                  +  N  +++  D + F  AD
Sbjct: 629 DGKVTWDEYLDKVYGFNKLDVDEMQKSVNEAKDKNTDEFKENVNNLELVDEDRKVFDAAD 450

Query: 165 KDGDLIATKEEFTAFLHPEEYDYMKDIVVQETMEDIDKNADGFIDLEEYIGDMYSHDGNA 224
            + D     +E+ AF  P  +  ++   ++  M   DKN DG I +EE++ +  + D   
Sbjct: 449 ANKDGSLNSKEYFAFFMPNSFPQLE---LERFMRQSDKNKDGTISMEEFMPEGATGD--- 288

Query: 225 DEPEWVKTEREQFVEFRDKNRDGKMDKEETKDWILPSDYDHAEAEARHLVYESDQNKDGK 284
                 +T  E+  +  DK++DG +  EE  +WI PS  +HA+ E  HL    D N DGK
Sbjct: 287 -----TRTSSEESFKNYDKDKDGSLSLEEAMEWINPSSDEHADVEVEHLFTIGDVNHDGK 123

Query: 285 LTKEEIVDKYDLFVGSQATDFGEALVRHDE 314
           L+K+EI++K D FVGS ATD+G  L++H+E
Sbjct: 122 LSKDEILNKADQFVGSAATDYGN-LIKHEE 36

 Score = 51.6 bits (122), Expect(2) = 1e-31,   Method: Compositional matrix adjust.
 Identities = 29/87 (33%), Positives = 43/87 (49%), Gaps = 2/87 (2%)
 Frame = -1

Query: 5   QFLMCLSLCTAFALSKPT-EKKDRVHHEPQLSDKVHNDAQNFDYDHDAFLGAEEAKS-FD 62
           Q + C  +  +  L       +++ HH P       +   N DYDH + LG+E     F+
Sbjct: 982 QMVQCCRVFVSLTLLMTVWGSREQAHHGPSAPHHTADGEHNPDYDHQSILGSEALDDDFE 803

Query: 63  QLTPEESKERLGKIVSKIDDDKDGFVT 89
            L+PEE+K RL  +V K D D D F+T
Sbjct: 802 GLSPEEAKXRLZNLVXKHDRDBDNFIT 722

 Score = 28.5 bits (62), Expect = 4.2,   Method: Compositional matrix adjust.
 Identities = 18/57 (31%), Positives = 29/57 (50%)
 Frame = -3

Query: 81  DDDKDGFVTVDELKGWIKFAQKRWIHEDVERQWKGHDLNEDGLVSWEEYKNATYGYV 137
           D DKDG ++++E   WI  +       +VE  +   D+N DG +S +E  N    +V
Sbjct: 251 DKDKDGSLSLEEAMEWINPSSDEHADVEVEHLFTIGDVNHDGKLSKDEILNKADQFV 81
>08380
          Length = 1236

 Score =  108 bits (269), Expect = 4e-24,   Method: Compositional matrix adjust.
 Identities = 97/326 (29%), Positives = 162/326 (49%), Gaps = 30/326 (9%)
 Frame = -1

Query: 20   KPTEKKDRVHHEPQLSDKVHNDAQNFDYDHDAFLGAEEAKSFDQLTPEESKERLGKIVSK 79
            +P E  D V  E       H+   N D+  + FLG  E    +     ESK  L  IV K
Sbjct: 1011 RPVEHMDAVKME-------HDGHMNKDFHKEMFLGNHEEFENEGYEEAESK--LKDIVYK 859

Query: 80   IDDDKDGFVTVDELKGWIK------FAQKRWIHEDVERQWKGHDLNEDGLVSWEEY---- 129
            +D DKDG ++V EL+ W+K      F++    +E++   +K  D + +G V W+EY    
Sbjct: 858  VDSDKDGKLSVAELEAWVKDKMEEHFSEATQENEEI---FKHLDPDNNGKVHWKEYYVHF 688

Query: 130  -------KNATYGYVLD------DPDPDDGFNYKQMMVRDERRFKMADKDGDLI---ATK 173
                   ++    +V+D      DPD       K+ ++R   +F+ +D DG+ +    T+
Sbjct: 687  LLAKGYKQDVASRHVVDYDZIQLDPDA------KEEIIR--YKFRWSDADGEPMDNELTR 532

Query: 174  EEFTAFLHPEEYDYMKDIVVQETMEDIDKNADGFIDLEEYI----GDMYSHDGNADEPEW 229
            EEF +F HPE+ +   + +V   +  ID N DG +  EE+     G++   +  A + +W
Sbjct: 531  EEFMSFRHPEQSEKTLNNMVNGILGGIDTNGDGVVTEEEFSALPPGEVEGEEYQAMDKQW 352

Query: 230  VKTEREQFVEFRDKNRDGKMDKEETKDWILPSDYDHAEAEARHLVYESDQNKDGKLTKEE 289
             K  +E+F    D + DGK+ K+E K ++ P +   A  EA+ LV   D +KDG +++ E
Sbjct: 351  QKERQEEFRTAIDLDHDGKVTKDEIKKYMDPRNPLQALLEAKSLVSYMDDDKDGMISQAE 172

Query: 290  IVDKYDLFVGSQATDFGEALVRHDEF 315
            ++   D+F+ S+  +F   +  HDEF
Sbjct: 171  VMRHKDIFISSKVMNFAANV--HDEF 100
>15966
          Length = 362

 Score = 33.5 bits (75), Expect = 0.13,   Method: Compositional matrix adjust.
 Identities = 21/78 (26%), Positives = 38/78 (48%)
 Frame = +2

Query: 56  EEAKSFDQLTPEESKERLGKIVSKIDDDKDGFVTVDELKGWIKFAQKRWIHEDVERQWKG 115
           E  K  DQ+      ++L ++    D   DG++  DELK  +  + +++  +DV    K 
Sbjct: 95  EFCKGLDQIVM--FVQKLAELFKAKDKSGDGYLDRDELKALLDESGQKFTADDVSAILKS 268

Query: 116 HDLNEDGLVSWEEYKNAT 133
            D N D  + +EE+ +A 
Sbjct: 269 ADKNNDNKICFEEFVDAC 322

 Score = 29.6 bits (65), Expect = 1.8,   Method: Compositional matrix adjust.
 Identities = 16/52 (30%), Positives = 28/52 (53%)
 Frame = +2

Query: 241 RDKNRDGKMDKEETKDWILPSDYDHAEAEARHLVYESDQNKDGKLTKEEIVD 292
           +DK+ DG +D++E K  +  S       +   ++  +D+N D K+  EE VD
Sbjct: 161 KDKSGDGYLDRDELKALLDESGQKFTADDVSAILKSADKNNDNKICFEEFVD 316
>01773
          Length = 1950

 Score = 33.1 bits (74), Expect = 0.13,   Method: Compositional matrix adjust.
 Identities = 17/63 (26%), Positives = 33/63 (52%)
 Frame = +1

Query: 71  ERLGKIVSKIDDDKDGFVTVDELKGWIKFAQKRWIHEDVERQWKGHDLNEDGLVSWEEYK 130
           ++L ++    D   DG++  DELK  +  + +++  +DV    K  D N D  + +EE+ 
Sbjct: 367 QKLAELFKAKDKSGDGYLDRDELKALLDESGQKFTADDVSAILKSADKNNDNKICFEEFV 546

Query: 131 NAT 133
           +A 
Sbjct: 547 DAC 555

 Score = 28.9 bits (63), Expect = 2.7,   Method: Compositional matrix adjust.
 Identities = 29/130 (22%), Positives = 58/130 (44%), Gaps = 31/130 (23%)
 Frame = +1

Query: 194 QETMEDIDKNADGFIDLEEYIGDMYSHDGNA-------------DEP--------EWVKT 232
           ++  ++ DKN DG+++++E + +++  +G++             D P        E    
Sbjct: 163 KQLFKEADKNNDGYLEIKE-LRELFKRNGSSLSDSQIADTFVFFDGPRGDKRITFEXFCK 339

Query: 233 EREQFVEF----------RDKNRDGKMDKEETKDWILPSDYDHAEAEARHLVYESDQNKD 282
             +Q V F          +DK+ DG +D++E K  +  S       +   ++  +D+N D
Sbjct: 340 GLDQIVMFVQKLAELFKAKDKSGDGYLDRDELKALLDESGQKFTADDVSAILKSADKNND 519

Query: 283 GKLTKEEIVD 292
            K+  EE VD
Sbjct: 520 NKICFEEFVD 549
>14594
          Length = 1014

 Score = 33.1 bits (74), Expect = 0.15,   Method: Compositional matrix adjust.
 Identities = 17/61 (27%), Positives = 34/61 (55%)
 Frame = +3

Query: 69  SKERLGKIVSKIDDDKDGFVTVDELKGWIKFAQKRWIHEDVERQWKGHDLNEDGLVSWEE 128
            +E L +     D D +G+++  EL+  +    ++   E+V+   K  DL+ DG+V++EE
Sbjct: 654 CEEELREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIKEADLDGDGMVNYEE 833

Query: 129 Y 129
           +
Sbjct: 834 F 836
>07678
          Length = 958

 Score = 32.7 bits (73), Expect = 0.20,   Method: Compositional matrix adjust.
 Identities = 41/155 (26%), Positives = 69/155 (44%), Gaps = 9/155 (5%)
 Frame = +1

Query: 158 RRFKMADKDGDLIATKEEFTAFLHPEEYDYMKDIVVQETMEDIDKNADGFIDLEEYIGDM 217
           R+FK+ D DG+     +EF   +        +  V+QE     DK+  G ID +E++  +
Sbjct: 331 RKFKIMDDDGNRSLDFKEFKKGITEFGLTQFEGDVIQEMFTCFDKDZSGTIDFDEFLVKL 510

Query: 218 YSHDGNADEPEWVKTEREQFVEFRDKNRDGKMDKEETK---DWILPSDYDHAE-AEARHL 273
                     +  K   ++  +  DK  DG +  E+ K   +      Y + E  E R L
Sbjct: 511 -----RPPMSQMRKDLIQRAFQKLDKTGDGVVTVEDLKGVYNVTKHPKYLNGEWTEERIL 675

Query: 274 -----VYESDQNKDGKLTKEEIVDKYDLFVGSQAT 303
                 ++S  +KDGK+TKEE    ++ +VG  A+
Sbjct: 676 RIFLDSFDSPNDKDGKITKEEF---FNYYVGVSAS 771

 Score = 27.3 bits (59), Expect = 8.9,   Method: Compositional matrix adjust.
 Identities = 24/85 (28%), Positives = 39/85 (45%), Gaps = 12/85 (14%)
 Frame = +1

Query: 63  QLTPEESKER---LGKIVSKIDDDKDGFVTVDELKGWI------KFAQKRWIHEDVERQW 113
           +L P  S+ R   + +   K+D   DG VTV++LKG        K+    W  E + R +
Sbjct: 505 KLRPPMSQMRKDLIQRAFQKLDKTGDGVVTVEDLKGVYNVTKHPKYLNGEWTEERILRIF 684

Query: 114 K---GHDLNEDGLVSWEEYKNATYG 135
                   ++DG ++ EE+ N   G
Sbjct: 685 LDSFDSPNDKDGKITKEEFFNYYVG 759
>17484
          Length = 471

 Score = 32.0 bits (71), Expect = 0.30,   Method: Compositional matrix adjust.
 Identities = 23/74 (31%), Positives = 34/74 (45%), Gaps = 2/74 (2%)
 Frame = -3

Query: 113 WKGHDLNEDGLVSWEEYKNAT--YGYVLDDPDPDDGFNYKQMMVRDERRFKMADKDGDLI 170
           ++  D N DG++S  E + A    G  L D D +        ++RD       DKDGD  
Sbjct: 253 FRAFDQNGDGVISISELRQAMAKMGQKLSDADVES-------IIRD------VDKDGDGF 113

Query: 171 ATKEEFTAFLHPEE 184
              EEFT F+  ++
Sbjct: 112 VNYEEFTKFIAGQQ 71

 Score = 29.6 bits (65), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 15/54 (27%), Positives = 30/54 (55%)
 Frame = -3

Query: 160 FKMADKDGDLIATKEEFTAFLHPEEYDYMKDIVVQETMEDIDKNADGFIDLEEY 213
           F+  D++GD + +  E    +  +    + D  V+  + D+DK+ DGF++ EE+
Sbjct: 253 FRAFDQNGDGVISISELRQAM-AKMGQKLSDADVESIIRDVDKDGDGFVNYEEF 95

 Score = 28.1 bits (61), Expect = 4.7,   Method: Compositional matrix adjust.
 Identities = 15/55 (27%), Positives = 28/55 (50%)
 Frame = -3

Query: 81  DDDKDGFVTVDELKGWIKFAQKRWIHEDVERQWKGHDLNEDGLVSWEEYKNATYG 135
           D + DG +++ EL+  +    ++    DVE   +  D + DG V++EE+     G
Sbjct: 241 DQNGDGVISISELRQAMAKMGQKLSDADVESIIRDVDKDGDGFVNYEEFTKFIAG 77
>14601
          Length = 472

 Score = 31.6 bits (70), Expect = 0.45,   Method: Compositional matrix adjust.
 Identities = 20/65 (30%), Positives = 30/65 (46%), Gaps = 9/65 (13%)
 Frame = +3

Query: 160 FKMADKDGDLIATKEEFTAFLH---------PEEYDYMKDIVVQETMEDIDKNADGFIDL 210
           FK  D + D + +++E +A+L          P         VV +  E  DK+ DGFI  
Sbjct: 18  FKQIDTNEDSLLSQDEVSAYLQQQRKSDPRAPPMNQMQHSTVVSQIFEHEDKDKDGFISH 197

Query: 211 EEYIG 215
           EE+ G
Sbjct: 198 EEFSG 212
>00167
          Length = 2176

 Score = 31.6 bits (70), Expect = 0.49,   Method: Compositional matrix adjust.
 Identities = 20/63 (31%), Positives = 33/63 (52%), Gaps = 2/63 (3%)
 Frame = +3

Query: 160 FKMADKDGDLIATKEEFTAFLHPEEYDYMKDIVVQETMEDIDKNADGFIDLEEYIG--DM 217
           F+  DKDG      EEF   L P+  ++ + + V++    +DK  DG I  ++ +G  D+
Sbjct: 858 FRRFDKDGTGTLDFEEFLLALRPKMNEFRRKL-VKKAFAKMDKTGDGIITADDLVGTYDV 1034

Query: 218 YSH 220
            SH
Sbjct: 1035RSH 1043
>39823
          Length = 655

 Score = 27.3 bits (59), Expect = 9.2,   Method: Compositional matrix adjust.
 Identities = 21/61 (34%), Positives = 29/61 (47%), Gaps = 1/61 (1%)
 Frame = +3

Query: 117 DLNEDGLVSWEEYKNATYGYVLDDPDPDDGFNYKQMMVRDER-RFKMADKDGDLIATKEE 175
           D + D  V+WEEY++A      D      G    +M  R  R  F+MAD+D D +    E
Sbjct: 87  DKDRDNQVTWEEYRDARSLTSKDPLARGQGRRMSEMTERVVRLEFQMADQDEDQVLDWWE 266

Query: 176 F 176
           F
Sbjct: 267 F 269
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6755566|ref|NP_036160.1| solute carrier family 9
(sodium/hydrogen exchanger), isoform 3 regulator 1 [Mus musculus]
         (355 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

03831                                                                 204   6e-53
38751                                                                  45   6e-05
29705                                                                  42   3e-04
20073                                                                  40   0.002
01502                                                                  38   0.007
02951                                                                  38   0.008
03499                                                                  37   0.016
08480                                                                  35   0.031
06410                                                                  30   1.6  
37239                                                                  28   4.6  
>03831
          Length = 1143

 Score =  204 bits (518), Expect = 6e-53,   Method: Compositional matrix adjust.
 Identities = 114/241 (47%), Positives = 149/241 (61%), Gaps = 16/241 (6%)
 Frame = +3

Query: 11  LPRLCCLEKGP--NGYGFHLHGEKGKVGQFIRLVEPGSPAEKSGLLAGDRLVEVNGENVE 68
           +PRLC + +    NGYGF+LH EKGK GQFI  V+ GSPAE +GL AGDR+VEVNG N+ 
Sbjct: 126 VPRLCHIVRWSDFNGYGFNLHAEKGKAGQFIGKVDEGSPAEAAGLKAGDRIVEVNGTNIG 305

Query: 69  KETHQQVVSRIRAALNAVRLLVVDPETDERLKKLGVSIREEL--------LRPQEKSEQA 120
            E HQQVV RI+A  +  RLLVVD ETD+  K+    +R +L         R Q+ + + 
Sbjct: 306 NENHQQVVGRIKAGGDETRLLVVDQETDQHYKEEKRVVRGDLPETRFMTAAREQKDNXEN 485

Query: 121 EPPAAADTHEAGDQNEAEKSHLRE----LRPRLCTMKKGP--NGYGFNLHSDKSKPGQFI 174
           +    A   EA +  E E   L +      PRLC + K    +GYGFNLH++K KPGQ+I
Sbjct: 486 QEAEIAAVVEATNGTEPEPQSLPDESSLYAPRLCHLCKWADFDGYGFNLHAEKDKPGQYI 665

Query: 175 RAVDPDSPAEASGLRAQDRIVEVNGVCMEGKQHGDVVSAIKGGGDEAKLLVVDKETDEFF 234
            +VDP+SPAE  GL+  DRI+EVNG  +E   H  V+  IK  GD+  +LVVDK  D ++
Sbjct: 666 GSVDPNSPAETGGLKEGDRIIEVNGENIETTNHTAVIQNIKSRGDKTSMLVVDKAADSYY 845

Query: 235 K 235
           K
Sbjct: 846 K 848

 Score =  112 bits (279), Expect = 3e-25,   Method: Compositional matrix adjust.
 Identities = 60/110 (54%), Positives = 75/110 (68%), Gaps = 2/110 (1%)
 Frame = +3

Query: 145 LRPRLCTMKKGP--NGYGFNLHSDKSKPGQFIRAVDPDSPAEASGLRAQDRIVEVNGVCM 202
           L PRLC + +    NGYGFNLH++K K GQFI  VD  SPAEA+GL+A DRIVEVNG  +
Sbjct: 123 LVPRLCHIVRWSDFNGYGFNLHAEKGKAGQFIGKVDEGSPAEAAGLKAGDRIVEVNGTNI 302

Query: 203 EGKQHGDVVSAIKGGGDEAKLLVVDKETDEFFKKCKVIPSQEHLDGPLPE 252
             + H  VV  IK GGDE +LLVVD+ETD+ +K+ K +     + G LPE
Sbjct: 303 GNENHQQVVGRIKAGGDETRLLVVDQETDQHYKEEKRV-----VRGDLPE 437

 Score = 90.9 bits (224), Expect = 7e-19,   Method: Compositional matrix adjust.
 Identities = 46/101 (45%), Positives = 60/101 (59%), Gaps = 2/101 (1%)
 Frame = +3

Query: 12  PRLCCLEKGPN--GYGFHLHGEKGKVGQFIRLVEPGSPAEKSGLLAGDRLVEVNGENVEK 69
           PRLC L K  +  GYGF+LH EK K GQ+I  V+P SPAE  GL  GDR++EVNGEN+E 
Sbjct: 576 PRLCHLCKWADFDGYGFNLHAEKDKPGQYIGSVDPNSPAETGGLKEGDRIIEVNGENIET 755

Query: 70  ETHQQVVSRIRAALNAVRLLVVDPETDERLKKLGVSIREEL 110
             H  V+  I++  +   +LVVD   D   K    +I   +
Sbjct: 756 TNHTAVIQNIKSRGDKTSMLVVDKAADSYYKNRAETISSSM 878
>38751
          Length = 329

 Score = 44.7 bits (104), Expect = 6e-05,   Method: Composition-based stats.
 Identities = 21/58 (36%), Positives = 35/58 (60%)
 Frame = +3

Query: 39  IRLVEPGSPAEKSGLLAGDRLVEVNGENVEKETHQQVVSRIRAALNAVRLLVVDPETD 96
           + ++E G  AE+ GL  GDR+++VNG +    TH + V+ +R A N +  +   PE+D
Sbjct: 45  VYVIEEGCQAEQQGLNIGDRILDVNGTDFTHLTHAEAVTIMRNAWNVIMTVQPCPESD 218
>29705
          Length = 674

 Score = 42.4 bits (98), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 24/62 (38%), Positives = 36/62 (58%), Gaps = 1/62 (1%)
 Frame = -1

Query: 33  GKVGQFIRLVEPGSPAEKSGLLA-GDRLVEVNGENVEKETHQQVVSRIRAALNAVRLLVV 91
           G  G FI  V  G  AE+ G +A  DRL+ VN  N+E  TH++ V+ +++  + VRL + 
Sbjct: 371 GDNGIFITKVIEGGSAEQDGRIAVMDRLLAVNEHNLEDVTHEEAVAALKSTGDVVRLTIA 192

Query: 92  DP 93
            P
Sbjct: 191 KP 186
>20073
          Length = 582

 Score = 40.0 bits (92), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 26/70 (37%), Positives = 42/70 (60%), Gaps = 2/70 (2%)
 Frame = +3

Query: 23 GYGFHLHGEKGKVG-QFIRLVEPGSPAEKSGLLA-GDRLVEVNGENVEKETHQQVVSRIR 80
          G GF++ G K +    +I  + PG  A++   L  GD+L+ VNG +VE E H++ V  ++
Sbjct: 3  GLGFNVMGGKEQSSPIYISRIIPGGVADRLNCLKRGDQLLSVNGVSVEGEYHEKAVELLK 182

Query: 81 AALNAVRLLV 90
           A  +VRL+V
Sbjct: 183LAQGSVRLVV 212
>01502
          Length = 1949

 Score = 37.7 bits (86), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 15/45 (33%), Positives = 27/45 (60%)
 Frame = +1

Query: 36 GQFIRLVEPGSPAEKSGLLAGDRLVEVNGENVEKETHQQVVSRIR 80
          G ++  +   SPA + GL   D+++++NG++    TH+Q V  IR
Sbjct: 34 GIYVTFIYENSPAARCGLQLHDKILQLNGKDFTVVTHKQAVENIR 168

 Score = 29.6 bits (65), Expect = 2.0,   Method: Compositional matrix adjust.
 Identities = 16/53 (30%), Positives = 27/53 (50%)
 Frame = +1

Query: 163 LHSDKSKPGQFIRAVDPDSPAEASGLRAQDRIVEVNGVCMEGKQHGDVVSAIK 215
           L+ DK   G ++  +  +SPA   GL+  D+I+++NG       H   V  I+
Sbjct: 19  LYPDK---GIYVTFIYENSPAARCGLQLHDKILQLNGKDFTVVTHKQAVENIR 168
>02951
          Length = 1076

 Score = 37.7 bits (86), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 15/45 (33%), Positives = 27/45 (60%)
 Frame = +2

Query: 36 GQFIRLVEPGSPAEKSGLLAGDRLVEVNGENVEKETHQQVVSRIR 80
          G ++  +   SPA + GL   D+++++NG++    TH+Q V  IR
Sbjct: 20 GIYVTFIYENSPAARCGLQLHDKILQLNGKDFTVVTHKQAVENIR 154
>03499
          Length = 1247

 Score = 36.6 bits (83), Expect = 0.016,   Method: Compositional matrix adjust.
 Identities = 25/70 (35%), Positives = 34/70 (48%), Gaps = 3/70 (4%)
 Frame = -3

Query: 15  CCLEKGPNGYGFHLHGEKGKVGQFIRL--VEPGSPAEKSGLL-AGDRLVEVNGENVEKET 71
             L K   G+GF + G      +F+++  V P  PA  +G L  GD +V VN   V   T
Sbjct: 972 TSLVKSVRGFGFTIVGSDHPDTEFLQIKNVVPNGPAYLNGKLKTGDVIVFVNTTCVLGYT 793

Query: 72  HQQVVSRIRA 81
           HQ VVS  + 
Sbjct: 792 HQDVVSLFQT 763
>08480
          Length = 698

 Score = 35.4 bits (80), Expect = 0.031,   Method: Compositional matrix adjust.
 Identities = 21/67 (31%), Positives = 38/67 (56%), Gaps = 2/67 (2%)
 Frame = -1

Query: 47  PAEKSG-LLAGDRLVEVNGENVEKETHQQVVSRIRAALNAVRLLV-VDPETDERLKKLGV 104
           PA+ SG L  GD+++ VN  +VE+ TH+Q    ++ A + V ++    PE   R +    
Sbjct: 695 PADLSGDLRRGDKILSVNDVDVERATHEQAAQALKRAGDTVEIIAQYKPEDYNRFEAKIQ 516

Query: 105 SIREELL 111
            +RE+++
Sbjct: 515 DLREQMM 495
>06410
          Length = 605

 Score = 30.0 bits (66), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 16/53 (30%), Positives = 24/53 (45%)
 Frame = -2

Query: 107 REELLRPQEKSEQAEPPAAADTHEAGDQNEAEKSHLRELRPRLCTMKKGPNGY 159
           +  L++P     QA  P   + H   D+ +  K H+R   P LCT    P+ Y
Sbjct: 181 QHSLIQPSRTQTQAS*PEQVNVHHIRDRKKPYKLHVR---PSLCTGLTSPSDY 32
>37239
          Length = 453

 Score = 28.5 bits (62), Expect = 4.6,   Method: Compositional matrix adjust.
 Identities = 16/56 (28%), Positives = 27/56 (48%), Gaps = 1/56 (1%)
 Frame = -2

Query: 179 PDSPAEASG-LRAQDRIVEVNGVCMEGKQHGDVVSAIKGGGDEAKLLVVDKETDEF 233
           PDSPA     +   D ++E+NG  + G+ H +  + +K        LVV++  D  
Sbjct: 449 PDSPAARDARIHVGDELLEINGNLLHGRCHLNASAIVKSVTAPDVKLVVNRRADSL 282

 Score = 27.3 bits (59), Expect = 9.9,   Method: Compositional matrix adjust.
 Identities = 28/123 (22%), Positives = 51/123 (41%), Gaps = 1/123 (0%)
 Frame = -2

Query: 43  EPGSPAEKSGLL-AGDRLVEVNGENVEKETHQQVVSRIRAALNAVRLLVVDPETDERLKK 101
           +P SPA +   +  GD L+E+NG  +    H    + +++       LVV+   D   + 
Sbjct: 452 QPDSPAARDARIHVGDELLEINGNLLHGRCHLNASAIVKSVTAPDVKLVVNRRADSLDR- 276

Query: 102 LGVSIREELLRPQEKSEQAEPPAAADTHEAGDQNEAEKSHLRELRPRLCTMKKGPNGYGF 161
             ++I+   + P   SE      ++D       +    S L ++   +   K+G  G GF
Sbjct: 275 --IAIKPLRMGPSIGSEGEASKPSSDKDSKQVTSRPSTSDLIQV---ITLHKQGTQGLGF 111

Query: 162 NLH 164
             H
Sbjct: 110 CHH 102
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|56119098|ref|NP_001007577.1| guanylate cyclase 2f
[Mus musculus]
         (1108 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

34057                                                                 141   8e-53
29215                                                                  97   4e-20
06405                                                                  88   2e-17
07291                                                                  72   1e-12
09007                                                                  71   2e-12
00715                                                                  68   3e-11
01718                                                                  67   3e-11
09572                                                                  64   4e-10
11780                                                                  47   2e-09
21808                                                                  60   3e-09
04852                                                                  60   4e-09
07833                                                                  56   7e-08
12721                                                                  54   3e-07
18996                                                                  53   5e-07
14116                                                                  53   8e-07
08294                                                                  51   3e-06
20640                                                                  50   5e-06
19301                                                                  49   9e-06
01966                                                                  47   3e-05
04591                                                                  47   5e-05
18921                                                                  46   8e-05
29581                                                                  46   8e-05
01756                                                                  46   8e-05
01060                                                                  46   9e-05
09606                                                                  45   2e-04
07940                                                                  44   3e-04
14420                                                                  44   3e-04
17300                                                                  44   4e-04
17637                                                                  41   0.002
13305                                                                  40   0.006
13592                                                                  40   0.008
17253                                                                  39   0.012
14126                                                                  37   0.036
21433                                                                  29   0.040
14477                                                                  37   0.042
27546                                                                  36   0.11 
25550                                                                  35   0.18 
35671                                                                  34   0.42 
00300                                                                  33   0.57 
32264                                                                  32   1.0  
07933                                                                  32   1.1  
19094                                                                  32   1.6  
04862                                                                  31   3.3  
27287                                                                  31   3.4  
13066                                                                  31   3.4  
03240                                                                  30   4.2  
37602                                                                  30   5.6  
04138                                                                  30   7.9  
>34057
          Length = 724

 Score =  141 bits (355), Expect(2) = 8e-53,   Method: Compositional matrix adjust.
 Identities = 67/120 (55%), Positives = 88/120 (73%)
 Frame = +3

Query: 850 KQKTEKLLTQMLPLSVAESLKKGCTVEPEGFDLVTLYFSDIVGFTTISAMSEPIEVVDLL 909
           K++T+ LL QMLP SVA+ LK+   V  E +   T++FSDI GFT ISA S P++VV++L
Sbjct: 126 KKRTDTLLYQMLPKSVADQLKRNEVVTAETYSESTIFFSDIQGFTQISARSSPVQVVEML 305

Query: 910 NDLYTLFDAIIGSHDVYKVETIGDAYMVASGLPKRNGSRHAAEIANMSLDILSSVGTFKM 969
           N LY  FD  +  +DVYKVETIGDAYMV SG+PK+NG RHAAEI  M+LD+L S+   ++
Sbjct: 306 NSLYLCFDERLALYDVYKVETIGDAYMVVSGVPKKNGKRHAAEIGTMTLDLLDSISRLEI 485

 Score = 85.9 bits (211), Expect(2) = 8e-53,   Method: Compositional matrix adjust.
 Identities = 42/74 (56%), Positives = 54/74 (72%)
 Frame = +2

Query: 971  HMPEVPVRIRIGLHSGPVVAGVVGLTMPRYCLFGDTVNTASRMESTGLPYRIHVSLSTVT 1030
            H+P    ++RIG HSGPVVAGVVG  MPRYCLFG+TV+ A++MES G P RIH+S +T  
Sbjct: 488  HLPGTKFKLRIGCHSGPVVAGVVGSKMPRYCLFGETVSVAAKMESLGKPGRIHISQTTHD 667

Query: 1031 ILQTLSEGYEVELR 1044
             L +L  G+ +E R
Sbjct: 668  ALLSLG-GFVMEQR 706
>29215
          Length = 698

 Score = 97.1 bits (240), Expect = 4e-20,   Method: Compositional matrix adjust.
 Identities = 48/83 (57%), Positives = 58/83 (69%)
 Frame = -1

Query: 992  VVGLTMPRYCLFGDTVNTASRMESTGLPYRIHVSLSTVTILQTLSEGYEVELRGRTELKG 1051
            VVG  MPRYCLFGDTVNTASRMESTG   +I VS  T   L +++  Y +E RG  E+KG
Sbjct: 698  VVGSKMPRYCLFGDTVNTASRMESTGEADKIQVSRGTYHALLSMTSEYTLEPRGAVEIKG 519

Query: 1052 KGTEETFWLVGKKGFTKPLPVPP 1074
            KG  +T+WL+ K+GF K LP  P
Sbjct: 518  KGPMDTYWLMDKEGFEKSLPCMP 450
>06405
          Length = 1965

 Score = 87.8 bits (216), Expect = 2e-17,   Method: Compositional matrix adjust.
 Identities = 77/280 (27%), Positives = 122/280 (43%), Gaps = 14/280 (5%)
 Frame = +1

Query: 565 IYEGDWVWLKKFPPGDFGDIKSIKSSA---SDVFE---MMKDLRHENVNPLLGFFYDSGM 618
           +YE  W    K        +K++K      +D  E   +MK+++H N+  LLG       
Sbjct: 307 VYEAMWKRYNKI-----VAVKTLKEDTMALNDFLEEAAIMKEMKHPNLVQLLGVCTREPP 471

Query: 619 FAIVSEFCSRRSLEDIL------TNDDVKLDWMFKSSLLLDLIKGMKYLHHREFIHGRLK 672
           F IV+EF    +L D L       N    L +M        +  GM YL  + FIH  L 
Sbjct: 472 FYIVTEFMPHGNLLDYLRSSTREENGPTALMYM-----ATQIASGMAYLETKNFIHRDLA 636

Query: 673 SRNCVVDGRFVLKVTDYGFNDIXXXXXXXXXXXXXXXXXWTAPELLRAPGGIRLGSFA-- 730
           +RNC+V    ++KV D+G   +                 WTAPE      G+    F+  
Sbjct: 637 ARNCLVADSNMVKVADFGLARLMKDDTYTAHIGAKFPIKWTAPE------GLAFNRFSTR 798

Query: 731 GDVYSFAIIMQEVMVRGAPFCMMDLPAKEIIDRLKMPPPVYRPVVSPEYAPAECLQLMKQ 790
            D+++F +++ E+    A + M   P  E+ +   +    YR +  P   PA+   LM +
Sbjct: 799 SDIWAFGVLLWEL----ATYGMSPYPGVELTEVYHLLERGYR-MERPPGTPADVYILMLK 963

Query: 791 CWAEASEQRPTFDEIFNQFKTFNKGKKTNIIDSMLRMLEQ 830
           CW    + RPTF EI   F   N  +K++I + + + LE+
Sbjct: 964 CWQWDPKDRPTFKEI--HFLLENMFEKSSICEEVEKELEK 1077
>07291
          Length = 833

 Score = 72.0 bits (175), Expect = 1e-12,   Method: Compositional matrix adjust.
 Identities = 50/164 (30%), Positives = 77/164 (46%), Gaps = 5/164 (3%)
 Frame = +1

Query: 654 LIKGMKYLHHREFIHGRLKSRNCVV--DGRFVLKVTDYGFND--IXXXXXXXXXXXXXXX 709
           +  GM YL   + +H  L +RNC+V  DGR  L+++DYG                     
Sbjct: 76  IADGMAYLQEVKVVHRNLAARNCIVTEDGR--LQLSDYGVTGSLFPQSYYTADDSPARDL 249

Query: 710 XXWTAPELLRAPGGIRLGSFAGDVYSFAIIMQEVMVRG-APFCMMDLPAKEIIDRLKMPP 768
             W APE +         S   DV++F +++ E++ RG  P+   D+    ++  LK   
Sbjct: 250 VKWMAPETI---DNFHFSS-KSDVWAFGVVLWELLTRGITPYP--DVENSSLLPYLKEGH 411

Query: 769 PVYRPVVSPEYAPAECLQLMKQCWAEASEQRPTFDEIFNQFKTF 812
            + +P  SPE       ++M  CW E+ EQRP F E+ +Q KTF
Sbjct: 412 RMKKPKQSPE----PVYEMMTACWNESPEQRPDFAELNDQLKTF 531
>09007
          Length = 1440

 Score = 71.2 bits (173), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 55/220 (25%), Positives = 98/220 (44%), Gaps = 10/220 (4%)
 Frame = -1

Query: 597 MMKDLRHENVNPLLGFFYDSGM-FAIVSEFCSRRSLEDILTNDDVKLDWMFKSSLLLD-- 653
           +M+ L HEN+  + G   D+G    +V+E    RSL + +     ++D  F    L D  
Sbjct: 717 IMQMLDHENIVRVYGVVMDNGADIMLVTELAPMRSLLECVKEVSARVD--FSVPRLCDFS 544

Query: 654 --LIKGMKYLHHREFIHGRLKSRNCVVDGRFVLKVTDYGFNDI----XXXXXXXXXXXXX 707
             +  GM YL  +  +H  L +RN ++  +  +K++D G +                   
Sbjct: 543 QQVCDGMSYLESKRLVHRDLAARNILLFSKSKVKISDVGVSGALGAGKEYYQSQQTIHLQ 364

Query: 708 XXXXWTAPELLRAPGGIRLGSFAGDVYSFAIIMQEVMVRG-APFCMMDLPAKEIIDRLKM 766
               W APE  R        S A DV++F +++ E    G  P+    L  ++I++ +  
Sbjct: 363 NAVAWCAPESFRN----LCFSSASDVWAFGVLLWEFFTHGFQPWA--GLNGQQIMEAVDA 202

Query: 767 PPPVYRPVVSPEYAPAECLQLMKQCWAEASEQRPTFDEIF 806
           P    + +  P+  P E   +M +CW +  ++RPTF ++F
Sbjct: 201 PQS--QRLEQPDLCPKEYYAVMLKCWEQEPQRRPTFSQLF 88
>00715
          Length = 1788

 Score = 67.8 bits (164), Expect = 3e-11,   Method: Compositional matrix adjust.
 Identities = 65/248 (26%), Positives = 101/248 (40%), Gaps = 34/248 (13%)
 Frame = +1

Query: 588 KSSASDVFEMMKDLRHENVNPLLGF-----FYDSGMFAIVSEFCSRRSLEDILTNDDVKL 642
           +S ++++      LRH NV  +LG      F D    A+  E+    +L+ IL +    +
Sbjct: 58  QSYSNELLAFRCGLRHVNVVSILGATSLHRFEDGAWLAM--EYVGPLNLQTILNDHQQDI 231

Query: 643 DWMFKSSLLLDLIKGMKYLHHREFIHGRLKSRNCVVDGRFVLKVTDYGF----------- 691
           D   + SL L + +G+ YLH    +H  LK  NC++     L++ D+G            
Sbjct: 232 DSSMRLSLALQMARGLHYLHSINIVHLDLKPANCLLTRDLKLRIADFGCCHQLTPTGLDM 411

Query: 692 ---------NDIXXXXXXXX-XXXXXXXXXWTAPELLRAPGGIRLGSFAGDVYSFAIIMQ 741
                    N++                  + APELL+   G++  S   DVYS  I + 
Sbjct: 412 GEREGGMAGNELELTPVQGAWKNELAGTLAYRAPELLK---GLQ-PSVRSDVYSLGITLW 579

Query: 742 EVMVRGAPFCMMDLPAKEII------DRLKMPPPVYRPVVSPEYAPAECL--QLMKQCWA 793
           ++  R  P+    +PA  ++      D    PPP      S E  P E +   L  QCWA
Sbjct: 580 QMCTRQGPY--EGVPAHAVVYQVVSKDLRPCPPP------STEDDPFEVMFRDLYTQCWA 735

Query: 794 EASEQRPT 801
              E RPT
Sbjct: 736 RRVEDRPT 759
>01718
          Length = 959

 Score = 67.4 bits (163), Expect = 3e-11,   Method: Compositional matrix adjust.
 Identities = 57/231 (24%), Positives = 95/231 (41%), Gaps = 6/231 (2%)
 Frame = +3

Query: 596 EMMKDLRHENVNPLLGFFYDSGMFAIVSEFCSRRSLEDILTNDDVKLDWMFKSSLLLDLI 655
           +++  L+H N+   +G     G    ++E+    +LE +L   D +L W  +  L L L 
Sbjct: 288 QLLNRLQHANILRFMGVCVHEGQLHALTEYIPSGNLEQLLEKKDEELPWTQRIQLTLGLA 467

Query: 656 KGMKYLHHREFIHGRLKSRNCVV----DGRFVLKVTDYGFNDIXXXXXXXXXXXXXXXXX 711
           +G+ YLH   FIH  L S+N ++    +  +   + D+G                     
Sbjct: 468 RGLDYLHSTRFIHRDLTSKNILIRREDNHGYHAVIADFGLATKIPDPLDKEKLPTVGSPY 647

Query: 712 WTAPELLRAPGGIRLGSFAGDVYSFAIIMQEVMVRGAPFCMMDLPAK-EIIDRLKMPPPV 770
           W APE+L         +   D++S  IIM E+  R        +PA  +I+ R+      
Sbjct: 648 WMAPEVLNG----HFYNERADLFSVGIIMCEITAR--------IPADPDIMPRMNNFGVD 791

Query: 771 YRPVVSP-EYAPAECLQLMKQCWAEASEQRPTFDEIFNQFKTFNKGKKTNI 820
           Y  +     Y P + LQL  +C     ++RP   EI    +   K  K +I
Sbjct: 792 YVALSEMISYCPLDYLQLAFKCCQVDPQKRPRGVEIIEWLEKIFKNLKNDI 944
>09572
          Length = 1081

 Score = 63.5 bits (153), Expect = 4e-10,   Method: Composition-based stats.
 Identities = 37/73 (50%), Positives = 45/73 (61%)
 Frame = -1

Query: 992  VVGLTMPRYCLFGDTVNTASRMESTGLPYRIHVSLSTVTILQTLSEGYEVELRGRTELKG 1051
            V+G T   Y ++GDTVN ASRM STG P RI V  ST   L  L E +E E RG   +KG
Sbjct: 1081 VIGTTKLLYDIWGDTVNIASRMYSTGEPDRIQVPQST---LPKLEEMFEFEYRGEIMVKG 911

Query: 1052 KGTEETFWLVGKK 1064
            KG  +T+ + GKK
Sbjct: 910  KGNMKTYLVKGKK 872
>11780
          Length = 1713

 Score = 47.4 bits (111), Expect(2) = 2e-09,   Method: Compositional matrix adjust.
 Identities = 46/163 (28%), Positives = 71/163 (43%), Gaps = 7/163 (4%)
 Frame = +3

Query: 564 AIYEGDWVWLKKFPPGDFGDIKSIKSSASDVFEMMKDLRHENVNPLLGFFYDSGMFAIVS 623
            +Y G  V +K+    D G+ +S    AS    +M  LRH+N+  L+G      +F +V+
Sbjct: 654 GMYRGQPVAIKQLKDKDRGE-QSFLQEAS----VMTSLRHDNLVRLIGVVLGETIF-LVT 815

Query: 624 EFCSRRSLEDILTNDD----VKLDWMFKSSLLLDLIKGMKYLHHREFIHGRLKSRNCVVD 679
           EF  + +L + L +       K D +   +   D    M+YL  +  +H  L +RN +V 
Sbjct: 816 EFMGKGNLVEYLRSRGRSVITKKDQI---NFATDTCAAMEYLESKRLVHRDLAARNVLVH 986

Query: 680 GRFVLKVTDYG---FNDIXXXXXXXXXXXXXXXXXWTAPELLR 719
                KV+D+G   F D                  WTAPE LR
Sbjct: 987 DDGKAKVSDFGLAKFGDF-------SQTSVKFPIKWTAPEALR 1094

 Score = 33.5 bits (75), Expect(2) = 2e-09,   Method: Compositional matrix adjust.
 Identities = 23/82 (28%), Positives = 37/82 (45%), Gaps = 1/82 (1%)
 Frame = +1

Query: 731  GDVYSFAIIMQEVMVRG-APFCMMDLPAKEIIDRLKMPPPVYRPVVSPEYAPAECLQLMK 789
             D++SF I++ E+   G  P+     P   + D +      YR + +PE  P E   +MK
Sbjct: 1117 SDMWSFGILLWEIYSFGRVPY-----PRIPLTDVVMHVERGYR-MEAPEGCPPEIYSIMK 1278

Query: 790  QCWAEASEQRPTFDEIFNQFKT 811
            Q W     +RPTF  +  +   
Sbjct: 1279 QAWELDPNERPTFKSVLARLNN 1344
>21808
          Length = 1011

 Score = 60.5 bits (145), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 54/224 (24%), Positives = 88/224 (39%), Gaps = 7/224 (3%)
 Frame = +1

Query: 584 IKSIKSSASD------VFEMMKDLRHENVNPLLGFFYDSGMFAIVSEFCSRRSLEDILTN 637
           IK++KS   D        ++MK LRH  +  L           I++E     SL + L  
Sbjct: 34  IKTLKSGTMDPKDFLAEAQIMKKLRHPKLIQLYAVCTQDDPIFIITELMKNGSLLEFLQG 213

Query: 638 DDVKLDWMFKSSLLLDLIKGMKYLHHREFIHGRLKSRNCVVDGRFVLKVTDYGFNDIXXX 697
               L       +   +  GM YL  + +IH  L +RN +V     +K+ D+G   +   
Sbjct: 214 KGRVLKLPALIDIGAQIACGMAYLESQNYIHRDLAARNILVSDNNTVKIADFGLARVIKE 393

Query: 698 XXXXXXXXXXXXXXWTAPELLRAPGGIRLGSFAGDVYSFAIIMQEVMVRG-APFCMMDLP 756
                         WTAPE           +   DV+SF I++ E +  G  P+  M   
Sbjct: 394 DEYEARVGARFPIKWTAPE----AANYNRFTIKSDVWSFGILLTETVTYGRVPYPGMT-- 555

Query: 757 AKEIIDRLKMPPPVYRPVVSPEYAPAECLQLMKQCWAEASEQRP 800
             E++ +++     YR +  P   P     +M +CW +   +RP
Sbjct: 556 NAEVLHQVEHG---YR-MPCPPGCPKPLYDIMLECWRKEEMERP 675
>04852
          Length = 1462

 Score = 60.1 bits (144), Expect = 4e-09,   Method: Compositional matrix adjust.
 Identities = 55/231 (23%), Positives = 92/231 (39%), Gaps = 28/231 (12%)
 Frame = +1

Query: 603 HENVNPLLGFFYDSGMFAIVSEFCSRRSLEDILTNDDVKLD------------WMFKS-- 648
           H N+   LG     G   ++ EF    +L D L +    ++            W  K+  
Sbjct: 127 HINIVNFLGCCTQGGPLWVIVEFAKNGNLRDFLESCRDGINGYGKFVSPQDPGWYTKTPG 306

Query: 649 ----------SLLLDLIKGMKYLHHREFIHGRLKSRNCVVDGRFVLKVTDYGFNDIXXXX 698
                     S    + +GM++L  R+ IH  L +RN +V    VLK+ D+G +      
Sbjct: 307 GHVIRRKNLLSYAFQIARGMEFLASRKCIHRDLAARNVLVTEEHVLKIADFGLS--RTGD 480

Query: 699 XXXXXXXXXXXXXWTAPELLRAPGGIRLGSFAGDVYSFAIIMQEVM-VRGAPFCMM---D 754
                        W APE L     +R  +   DV+SF +++ E+  + G P+  +   +
Sbjct: 481 YYKKRSGGRLPVKWMAPEALF---DMRYTT-KSDVWSFGVVLWEIFSLGGMPYASIPNEE 648

Query: 755 LPAKEIIDRLKMPPPVYRPVVSPEYAPAECLQLMKQCWAEASEQRPTFDEI 805
           L +K + D  +MP         PE A      +M++CW      RP F ++
Sbjct: 649 LYSKLLDDAYRMP--------RPELASGNLYAIMERCWLNRPSDRPEFSQL 777
>07833
          Length = 1504

 Score = 56.2 bits (134), Expect = 7e-08,   Method: Compositional matrix adjust.
 Identities = 60/230 (26%), Positives = 100/230 (43%), Gaps = 9/230 (3%)
 Frame = -3

Query: 585  KSIKSSASDVFEMMKDLRHENVNPLLGFFYDSGMFAIVSEFCSRRSLEDILTNDD-VKLD 643
            K I     + F  ++   H NV P+L          ++S+F    SL + L  +  + +D
Sbjct: 1496 KRITRDFMEEFPRLRIFNHPNVLPVLACCNQPPNLVLISQFMPFGSLYNTLHGESGIVVD 1317

Query: 644  WMFKSSLLLDLIKGMKYLHHRE--FIHGRLKSRNCVVDGRFVLKVT--DYGFNDIXXXXX 699
                    +D+ +GM++LH  E    +  L S++ ++D     ++   DY F+       
Sbjct: 1316 QNQSLRFAMDIARGMEFLHSMEPTIPNFLLTSKHVMIDEDLTARINMADYCFS------- 1158

Query: 700  XXXXXXXXXXXXWTAPELL-RAPGGIRLGSFAGDVYSFAIIMQEVMVRGAPFC---MMDL 755
                        W APE L R P  I   + A D++SFAI+M E+  R  PF     M++
Sbjct: 1157 -FHEKGKVYSPAWMAPEALQRRPDDI--NTRAADMWSFAILMWELETREVPFAELSSMEV 987

Query: 756  PAKEIIDRLKMPPPVYRPVVSPEYAPAECLQLMKQCWAEASEQRPTFDEI 805
              K  ++ L++  P   P +S   +     +L+K C  E   +RP FD I
Sbjct: 986  GMKVALEGLRISIP---PGISLHMS-----RLIKICMNEEPGKRPRFDMI 861
>12721
          Length = 821

 Score = 54.3 bits (129), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 44/178 (24%), Positives = 84/178 (47%), Gaps = 2/178 (1%)
 Frame = +1

Query: 597 MMKDLRHENVNPLLGFFYDSGMFAIVSEFCSRRSLEDILTNDDVKLDWMFKSSLLLDLIK 656
           +M+D  H N+  +   +  +    +V EF    +L DI+TN+  ++D +  +++    +K
Sbjct: 235 VMRDYHHPNIVEMYNSYLVNDELWVVMEFMEGGALTDIVTNN--RMDEVQIATVCRACLK 408

Query: 657 GMKYLHHREFIHGRLKSRNCVVDGRFVLKVTDYGFNDIXXXXXXXXXXXXXXXXXWTAPE 716
            + +LH    IH  +KS + ++     +K+ D+GF                    W APE
Sbjct: 409 ALAFLHANGVIHRDIKSDSILLSHDGKVKLXDFGFC-AQVTQDLQKRKSLVGTPYWMAPE 585

Query: 717 LL-RAPGGIRLGSFAGDVYSFAIIMQEVMVRGAPFCMMDLPAKEIIDRLK-MPPPVYR 772
           ++ R P G  +     D++S  I++ E++    PF   + P  + + R++ MPPP  R
Sbjct: 586 VISRLPYGPEV-----DIWSLGIMVMEMIDAEPPF--FNEPPLQAMRRIRDMPPPKLR 738
>18996
          Length = 491

 Score = 53.1 bits (126), Expect = 5e-07,   Method: Compositional matrix adjust.
 Identities = 38/143 (26%), Positives = 69/143 (48%), Gaps = 4/143 (2%)
 Frame = +2

Query: 667 IHGRLKSRNCVVDGRFVLKVTDYGFNDIXXXXXXXXXXXXXXX-XXWTAPELLRAPGGIR 725
           IH  L +RN +VD R  +K++D+G                      W +PE +      +
Sbjct: 2   IHRDLAARNILVD-RSCVKISDFGLAQFANADGYYYGISQRDIPIKWYSPEAIET---CK 169

Query: 726 LGSFAGDVYSFAIIMQEVMVRGAPFCMM---DLPAKEIIDRLKMPPPVYRPVVSPEYAPA 782
             S++ DV+S+ + + E+  RG    ++   DL  +E ++RL+    + +P +  ++  +
Sbjct: 170 FSSYS-DVWSYGVTLFEMFSRGEIPNLLPGHDLTQEEFLNRLRKGERLPKPELCSDFVYS 346

Query: 783 ECLQLMKQCWAEASEQRPTFDEI 805
           E   LM+ CW E  + RPTF +I
Sbjct: 347 E---LMRPCWHEMPKSRPTFHQI 406
>14116
          Length = 1017

 Score = 52.8 bits (125), Expect = 8e-07,   Method: Compositional matrix adjust.
 Identities = 45/161 (27%), Positives = 73/161 (45%), Gaps = 9/161 (5%)
 Frame = -1

Query: 597 MMKDLRHENVNPLLGFFYD-SGMFAIVSEFCSRRSLEDILTNDD----VKLDWMFKSSLL 651
           +MKD  H NV  L+G   +   M  +V  F     L   + +D     +K   M+     
Sbjct: 468 IMKDFHHSNVLTLIGICLNLDDMPLVVLPFMKHGDLLTYIRDDQHQPTIKDLIMYG---- 301

Query: 652 LDLIKGMKYLHHREFIHGRLKSRNCVVDGRFVLKVTDYGF-NDIXXXXXXXXXXXXXXX- 709
           +D+ +GM YL   +F+H  L +RNC++D  F +KV D+G   DI                
Sbjct: 300 VDIARGMDYLAGLKFVHRDLAARNCMLDEDFHVKVADFGLARDIYEKEYYSSENKKAKLP 121

Query: 710 XXWTAPELLRAPGGIRLGSFAG--DVYSFAIIMQEVMVRGA 748
             W A E L        G++    DV+S+ +++ E++ RG+
Sbjct: 120 VKWMALESLEK------GNYDSKTDVWSYGVVLWELLTRGS 16
>08294
          Length = 1849

 Score = 50.8 bits (120), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 50/214 (23%), Positives = 88/214 (41%), Gaps = 13/214 (6%)
 Frame = +2

Query: 605  NVNPLLGFFYDSGMFAIVSEFCSRRSLEDIL---TNDDVK--------LDWMFKSSLLLD 653
            N+   +G   ++    +++E+C    L+  L    ND+ +        L    K  +   
Sbjct: 890  NIVHFMGVCREAEPHFLITEYCDWGDLKQFLLATRNDNGRGRGTRVPALALSQKLGMGQQ 1069

Query: 654  LIKGMKYLHHREFIHGRLKSRNCVVDGRFVLKVTDYGFNDIXXXXXXXXXXXXXXXXXWT 713
            +  GM+ L ++  +HG L +RN ++  R  LKV     +                   W 
Sbjct: 1070 VAAGMEALSNQGLVHGDLAARNVLLTSRMQLKVARPALSGDVYASEYYPLHQRLVPLRWL 1249

Query: 714  APELLRAPGGIRLGSFAGDVYSFAIIMQEVMVRGAPFCMMDLPAKEIIDR--LKMPPPVY 771
             PE +         +  GDV++F + + EV+       + DLP + + D   L+      
Sbjct: 1250 PPEGVLEDS----ATTCGDVWAFGVFLWEVLQ------LADLPYRLMSDEEVLRSLQHSQ 1399

Query: 772  RPVVSPEYAPAECLQLMKQCWAEASEQRPTFDEI 805
              + SP+ AP   L L+++C A+   QRP F EI
Sbjct: 1400 AALDSPD-APPALLSLLQRCTAQQPSQRPPFSEI 1498
>20640
          Length = 1492

 Score = 50.1 bits (118), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 37/160 (23%), Positives = 65/160 (40%), Gaps = 4/160 (2%)
 Frame = +1

Query: 664 REFIHGRLKSRNCVVDGRFVLKVTDYGF-NDIXXXXXXXXXXXXXXXXXWTAPELLRAPG 722
           R ++H  L +RNC+V    V+K++D+G    +                 W   E      
Sbjct: 1   RGYVHRDLATRNCLVGHDLVVKISDFGLARSVHSVDYYRGSEHDAIPIRWMPLE------ 162

Query: 723 GIRLGSFA--GDVYSFAIIMQEVMVRG-APFCMMDLPAKEIIDRLKMPPPVYRPVVSPEY 779
            I    F+   DV+SF +++ E+      P+    L  +E++  +K      + +  PE 
Sbjct: 163 AILYNKFSTQSDVWSFGVVLWEIFAFALQPY--YGLTHEEVVRFVKEG----KVLACPER 324

Query: 780 APAECLQLMKQCWAEASEQRPTFDEIFNQFKTFNKGKKTN 819
            P    +LMKQCW      RP+F  +    +  +   + N
Sbjct: 325 TPPPMYELMKQCWHRRPATRPSFHTLHKTLENMHSKYEKN 444
>19301
          Length = 712

 Score = 49.3 bits (116), Expect = 9e-06,   Method: Compositional matrix adjust.
 Identities = 29/112 (25%), Positives = 51/112 (45%), Gaps = 5/112 (4%)
 Frame = +2

Query: 584 IKSIKSSASDVFEMMKDLRHENVNPLLGFFYDSGMFAIVSEFCSRRSLEDILTNDD---- 639
           +K ++         ++ L H N+    G    +  + I+ E+C    L ++L +      
Sbjct: 389 VKKVRDIKETDIRNLRKLNHPNIISFKGVCTQAPCYCIIMEYCPYGQLYEVLRDGKEIPP 568

Query: 640 -VKLDWMFKSSLLLDLIKGMKYLHHREFIHGRLKSRNCVVDGRFVLKVTDYG 690
            + LDW  +      +  GM YLH  + IH  LKS N +V    V+K++D+G
Sbjct: 569 ALVLDWSKQ------IASGMNYLHSHKIIHRDLKSPNVLVAKNDVVKISDFG 706
>01966
          Length = 1735

 Score = 47.4 bits (111), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 29/112 (25%), Positives = 52/112 (46%), Gaps = 2/112 (1%)
 Frame = -1

Query: 582  GDIKSIKSSASDVFEMMKDLRHENVNPLLGFFYDSGMFAIVSEFCSRRSLEDILTN--DD 639
            G    + SSA     M+++LRH N+  L     +     +V EF S   L+  +    + 
Sbjct: 1600 GSEDGVPSSAIREIAMLRELRHTNIVCLEDVIMEDERLFLVFEFLSM-DLKMYIDKFPEG 1424

Query: 640  VKLDWMFKSSLLLDLIKGMKYLHHREFIHGRLKSRNCVVDGRFVLKVTDYGF 691
            V LD     S +  ++ G+ + H R  +H  LK +N +++    +K+ D+G 
Sbjct: 1423 VVLDRRLVKSYVFQIVTGINFCHQRRIVHRDLKPQNLLINHTGAIKIADFGM 1268
>04591
          Length = 1117

 Score = 46.6 bits (109), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 29/123 (23%), Positives = 58/123 (47%)
 Frame = -2

Query: 570  WVWLKKFPPGDFGDIKSIKSSASDVFEMMKDLRHENVNPLLGFFYDSGMFAIVSEFCSRR 629
            W   + FP     +IK ++    +    ++++ H    P   +      F ++ E+C   
Sbjct: 1110 WK*KEGFPITALREIKILQQLEHENVVQLQEICHTQAGPYNRY---KSTFYLIFEYCDY- 943

Query: 630  SLEDILTNDDVKLDWMFKSSLLLDLIKGMKYLHHREFIHGRLKSRNCVVDGRFVLKVTDY 689
             L  +L N  VK     K +L+  L+ G+ Y+H ++ +H  +K+ N ++    VLK+ D+
Sbjct: 942  DLAGLLNNLRVKFSLADKKNLMSQLLNGLFYIHTKQILHRDIKAANILLTRDGVLKLADF 763

Query: 690  GFN 692
            G +
Sbjct: 762  GLS 754
>18921
          Length = 697

 Score = 46.2 bits (108), Expect = 8e-05,   Method: Compositional matrix adjust.
 Identities = 37/156 (23%), Positives = 65/156 (41%)
 Frame = +2

Query: 597 MMKDLRHENVNPLLGFFYDSGMFAIVSEFCSRRSLEDILTNDDVKLDWMFKSSLLLDLIK 656
           +M+    + +    G ++ +    IV E+C   S+ DI+   +  L     +++L   +K
Sbjct: 173 IMQQCDSKYIVKYYGSYFKNTDLWIVMEYCGAGSVSDIMRLRNKTLVEREIATILYYTLK 352

Query: 657 GMKYLHHREFIHGRLKSRNCVVDGRFVLKVTDYGFNDIXXXXXXXXXXXXXXXXXWTAPE 716
           G+ YLH R  IH  +K+ N +++     K+ D+G                     W APE
Sbjct: 353 GLXYLHSRRKIHRDIKAGNILLNNEGHAKLADFGVAG-QLTDTMAKRNTVIGTPYWMAPE 529

Query: 717 LLRAPGGIRLGSFAGDVYSFAIIMQEVMVRGAPFCM 752
           +++  G         D++S  I   E M  G P  M
Sbjct: 530 VIQEIG----YDCVADIWSLGITALE-MAEGKPPVM 622
>29581
          Length = 1278

 Score = 46.2 bits (108), Expect = 8e-05,   Method: Compositional matrix adjust.
 Identities = 41/149 (27%), Positives = 67/149 (44%), Gaps = 4/149 (2%)
 Frame = -2

Query: 600  DLRHENVNPL----LGFFYDSGMFAIVSEFCSRRSLEDILTNDDVKLDWMFKSSLLLDLI 655
            +LRH+N+  L    +G   DS    +V E+C +  L  +L N            ++L L+
Sbjct: 1187 NLRHQNIVQLQEVVVGKSLDS--LFLVMEYCEQ-DLASLLDNMPAPFSESQVKCIVLQLL 1017

Query: 656  KGMKYLHHREFIHGRLKSRNCVVDGRFVLKVTDYGFNDIXXXXXXXXXXXXXXXXXWTAP 715
            KG++YLH    IH  LK  N ++  +  +K+ D+G                     + AP
Sbjct: 1016 KGLRYLHEAFIIHRDLKVSNLLMTDKGCVKIADFGLAR-NYGKPQKPMTPKVVTLWYRAP 840

Query: 716  ELLRAPGGIRLGSFAGDVYSFAIIMQEVM 744
            ELL    G +  S A D++S   I+ E++
Sbjct: 839  ELL---FGSKTHSTAIDMWSAGCILGELL 762
>01756
          Length = 1858

 Score = 45.8 bits (107), Expect = 8e-05,   Method: Compositional matrix adjust.
 Identities = 28/105 (26%), Positives = 51/105 (48%), Gaps = 8/105 (7%)
 Frame = -3

Query: 595  FEMMKDLRHENVNPLLGFFYDSG--------MFAIVSEFCSRRSLEDILTNDDVKLDWMF 646
             ++++ L HENV  L+               MF +V EFC    L  +L+N  V  +   
Sbjct: 1592 IKILQLLNHENVVDLIEICSTKATSANRYKSMFYLVFEFCEH-DLAGLLSNMSVVFNLPE 1416

Query: 647  KSSLLLDLIKGMKYLHHREFIHGRLKSRNCVVDGRFVLKVTDYGF 691
               ++  L+ G+ Y+H  + +H  +K+ N ++  + VLK+ D+G 
Sbjct: 1415 IKEVMKQLMNGLYYIHRNKILHRDMKAANILITKQGVLKLADFGL 1281
>01060
          Length = 1800

 Score = 45.8 bits (107), Expect = 9e-05,   Method: Compositional matrix adjust.
 Identities = 41/171 (23%), Positives = 71/171 (41%), Gaps = 2/171 (1%)
 Frame = +1

Query: 582 GDIKSIKSSASDVFEMMKDLRHENVNPLLGFFYDSGMFAIVSEFCSRRSLEDILTN--DD 639
           G    + SSA     M+++LRH N+  L     +     +V EF S   L+  +    + 
Sbjct: 184 GSEDGVPSSAIREIAMLRELRHTNIVCLEDVIMEDERLFLVFEFLSM-DLKMYIDKFPEG 360

Query: 640 VKLDWMFKSSLLLDLIKGMKYLHHREFIHGRLKSRNCVVDGRFVLKVTDYGFNDIXXXXX 699
           V LD     S +  ++ G+ + H R  +H  LK +N +++    +K+ D+G         
Sbjct: 361 VVLDRRLVKSYVFQIVTGIXFCHQRRIVHRDLKPQNLLINHTGAIKIADFGMAR-TFALP 537

Query: 700 XXXXXXXXXXXXWTAPELLRAPGGIRLGSFAGDVYSFAIIMQEVMVRGAPF 750
                       + APE+L    G    S   DV+S   I  ++++R   F
Sbjct: 538 VRAYTHEVVTLWYRAPEILM---GASKYSTPVDVWSIGTIFADMLIRTPIF 681
>09606
          Length = 1300

 Score = 44.7 bits (104), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 28/110 (25%), Positives = 47/110 (42%)
 Frame = -3

Query: 585  KSIKSSASDVFEMMKDLRHENVNPLLGFFYDSGMFAIVSEFCSRRSLEDILTNDDVKLDW 644
            K  +   ++   M  D+ H NV     ++  S    +V E C+  SL DIL  D   L  
Sbjct: 1010 KCKRPEVTNTVRMTHDISHPNVVQFHEWYETSNHLWLVVELCTGGSLADILAQDH-HLPE 834

Query: 645  MFKSSLLLDLIKGMKYLHHREFIHGRLKSRNCVVDGRFVLKVTDYGFNDI 694
                   + L+ G+ Y+H    +   L+    ++D   VLK  D+G + +
Sbjct: 833  TSIRDFGIHLVTGLHYIHSLGILFHDLRPSKVLLDTSGVLKFADFGLSKV 684
>07940
          Length = 1336

 Score = 44.3 bits (103), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 26/94 (27%), Positives = 44/94 (46%), Gaps = 1/94 (1%)
 Frame = -3

Query: 656 KGMKYLHHREFIHGRLKSRNCVVDGRFVLKVTDYGFN-DIXXXXXXXXXXXXXXXXXWTA 714
           +GM+YL  ++ IH  L +RN +V   +VLK+ D+G   ++                 W A
Sbjct: 314 RGMEYLASKQCIHRDLAARNVLVAEEYVLKIADFGLTRNLQQFDYYRKTTDGRLPVKWMA 135

Query: 715 PELLRAPGGIRLGSFAGDVYSFAIIMQEVMVRGA 748
           PE L      R  +   DV+S+ +++ E+   G 
Sbjct: 134 PEALFD----RKYTSKSDVWSYGVLLWEIFTLGG 45
>14420
          Length = 528

 Score = 44.3 bits (103), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 38/152 (25%), Positives = 71/152 (46%), Gaps = 5/152 (3%)
 Frame = +2

Query: 603 HENVNPLLGFFYDSGMFA----IVSEFCSRRSLEDILTNDDVKLDWMFKSSLLLDLIKGM 658
            EN NP +  + DS +      +V EF +  SL D++T  +  +D    +++  + ++ +
Sbjct: 65  RENQNPNIVNYLDSYLVGEELWVVMEFLAGGSLTDVVT--ETCMDEGQIAAVCRECLQAL 238

Query: 659 KYLHHREFIHGRLKSRNCVVDGRFVLKVTDYGFNDIXXXXXXXXXXXXXXXXXWTAPELL 718
           ++LH  + IH  +KS N ++     +K+TD+GF                    W APE++
Sbjct: 239 EFLHENQVIHRDIKSDNILLGMDGSVKLTDFGFC-AQLSPEQSKRSTMVGTPYWMAPEVV 415

Query: 719 -RAPGGIRLGSFAGDVYSFAIIMQEVMVRGAP 749
            R   G  +     D++S  ++  E M+ G P
Sbjct: 416 TRKQYGPTV-----DIWSLGVMCIE-MIEGEP 493
>17300
          Length = 480

 Score = 43.5 bits (101), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 29/94 (30%), Positives = 42/94 (44%), Gaps = 3/94 (3%)
 Frame = +1

Query: 657 GMKYLHHREFIHGRLKSRNCVVDGRFVLKVTDYGFN---DIXXXXXXXXXXXXXXXXXWT 713
           GM  L    ++H  L +RN +V+   V KV D+G +   +                  WT
Sbjct: 10  GMGXLADMGYVHRDLAARNILVNEILVCKVADFGLSREIESDTTEGAYTTKGGKIPVRWT 189

Query: 714 APELLRAPGGIRLGSFAGDVYSFAIIMQEVMVRG 747
           APE +      R  + A DV+SF ++M EVM  G
Sbjct: 190 APEAI----AYRKFTSASDVWSFGVVMWEVMSYG 279
>17637
          Length = 447

 Score = 41.2 bits (95), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 38/135 (28%), Positives = 58/135 (42%), Gaps = 4/135 (2%)
 Frame = +1

Query: 675 NCVVDGRFVLKVTDYGFN-DIXXXXXXXXXXXXXXXXXWTAPELLRAPGGIRLGSFAGDV 733
           NCV+D +  +K+TD   + D+                 W + E L+       GS   DV
Sbjct: 1   NCVIDDQLRVKLTDSALSRDLFSGDYNCLGDGEYRPIKWLSLEALQK-SHYNEGS---DV 168

Query: 734 YSFAIIMQEVMVRGAPFCMMDLPAKEIIDRLKMPPPV---YRPVVSPEYAPAECLQLMKQ 790
           +SF ++M E+   G       LP  EI D  +M   +   YR +  P   P E   +M  
Sbjct: 169 WSFGVLMWEMCTLGK------LPYAEI-DPYEMEHYLKDGYR-LAQPFNCPDELFTIMAY 324

Query: 791 CWAEASEQRPTFDEI 805
           CWA    +RP+F ++
Sbjct: 325 CWASMPAERPSFSQL 369
>13305
          Length = 549

 Score = 39.7 bits (91), Expect = 0.006,   Method: Composition-based stats.
 Identities = 23/75 (30%), Positives = 41/75 (54%), Gaps = 1/75 (1%)
 Frame = +2

Query: 732 DVYSFAIIMQEVM-VRGAPFCMMDLPAKEIIDRLKMPPPVYRPVVSPEYAPAECLQLMKQ 790
           DV+SF +++ E+  + G P+   D   +++   LK    + RP +  +   A    +M Q
Sbjct: 71  DVWSFGVVLWEIFTLGGTPYSSTD--TQQLFAFLKDGYRLKRPKLCDQNTYA----MMLQ 232

Query: 791 CWAEASEQRPTFDEI 805
           CW E +++RPTF E+
Sbjct: 233 CWNENAQRRPTFPEL 277
>13592
          Length = 980

 Score = 39.7 bits (91), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 49/230 (21%), Positives = 91/230 (39%), Gaps = 3/230 (1%)
 Frame = +2

Query: 582 GDIKSIKSSASDVFEMMKDLRHENVNPLLGFFYDSGMFAIVSEFCSRRSLEDILTNDDVK 641
           G+ +++K+ A ++ ++++ ++H+N+    G         I  E CS  +LE  L      
Sbjct: 98  GETRALKNVAEEL-KILEGIKHKNLVRYYGIEVHREELLIFMELCSEGTLES-LVELTGG 271

Query: 642 LDWMFKSSLLLDLIKGMKYLHHREFIHGRLKSRNC-VVDGRFVLKVTDYG--FNDIXXXX 698
           L           L+ G+  LH    +H  +K+ N  +VDG   LK+ D+G          
Sbjct: 272 LPEALSRRFTAQLLSGVAELHKHGIVHRDIKTANIFLVDGSNSLKLGDFGSAVKIQAHTT 451

Query: 699 XXXXXXXXXXXXXWTAPELLRAPGGIRLGSFAGDVYSFAIIMQEVMVRGAPFCMMDLPAK 758
                        + APE+         G  A D++S   ++ E+     P+   D    
Sbjct: 452 VPGELQGYVGTQAYMAPEVFTKTNSDGHGRLA-DIWSVGCVVVEMASGKRPWAQFD-SNF 625

Query: 759 EIIDRLKMPPPVYRPVVSPEYAPAECLQLMKQCWAEASEQRPTFDEIFNQ 808
           +I+ ++ M     +P  +PE    E    +  C     +QR +  E+  Q
Sbjct: 626 QIMFKVGMGE---KP-QAPESLSQEGHDFIDHCLQHDPKQRLSAIELLEQ 763
>17253
          Length = 483

 Score = 38.9 bits (89), Expect = 0.012,   Method: Composition-based stats.
 Identities = 30/110 (27%), Positives = 47/110 (42%), Gaps = 14/110 (12%)
 Frame = -1

Query: 597 MMKDLRHENVNPLLGFFYDSGMFAIVSEFCSRRSLEDIL--------------TNDDVKL 642
           M K  RH NV   +G    S    I+ EFC    L   L               ND    
Sbjct: 387 MRKLPRHPNVVSFMGCCTMSDPALILMEFCCHGDLLSFLRKRRPDRTVFLTSTANDLTAR 208

Query: 643 DWMFKSSLLLDLIKGMKYLHHREFIHGRLKSRNCVVDGRFVLKVTDYGFN 692
           D+    S  L + +GM ++ + + +H  + +RN ++  R V KV+D+G +
Sbjct: 207 DFF---SFALHVARGMAHVANNKIVHRDVAARNVLISERNVCKVSDFGLS 67
>14126
          Length = 1265

 Score = 37.4 bits (85), Expect = 0.036,   Method: Compositional matrix adjust.
 Identities = 47/190 (24%), Positives = 79/190 (41%), Gaps = 14/190 (7%)
 Frame = +3

Query: 650 LLLDLIKGMKYLHHREFIHGRLKSRNCVV--DGRFVLKVTDYGFNDIXXXXXXXXXXXXX 707
           L+L L+ G+ +LH    +H  LK +N ++  DGR  LK+ D+G   I             
Sbjct: 531 LMLQLLNGVDFLHSNRIVHRDLKPQNLLISKDGR--LKLADFGLARI--YSFHMALTTVV 698

Query: 708 XXXXWTAPE-LLRAPGGIRLGSFAGDVYSFAIIMQEVMVRGAPF---CMMDLPAKEIIDR 763
               + +PE L++A  G  +     D++S   I  E+  R A F      D   K+I + 
Sbjct: 699 VTLWYRSPEVLMQAEYGTSV-----DIWSCGCIFAELFTRRALFKGSSEFD-QLKKIFEV 860

Query: 764 LKMPPP--------VYRPVVSPEYAPAECLQLMKQCWAEASEQRPTFDEIFNQFKTFNKG 815
           + +PP         V+R    P   P   LQ +        E  P   ++  +   F  G
Sbjct: 861 IGLPPAGDWPEGVSVHRNSFRP--TPPVPLQTL------VPEMDPQAKDLMEKMLVFKSG 1016

Query: 816 KKTNIIDSML 825
           ++ +  +S+L
Sbjct: 1017RRISSRESLL 1046
>21433
          Length = 590

 Score = 29.3 bits (64), Expect(2) = 0.040,   Method: Composition-based stats.
 Identities = 11/36 (30%), Positives = 20/36 (55%)
 Frame = +3

Query: 596 EMMKDLRHENVNPLLGFFYDSGMFAIVSEFCSRRSL 631
           E+   LRH+N+  + G+F+D     ++ EF  +  L
Sbjct: 24  EIQSHLRHDNILRMFGYFHDKTRVYLILEFAPKGEL 131

 Score = 26.6 bits (57), Expect(2) = 0.040,   Method: Compositional matrix adjust.
 Identities = 12/42 (28%), Positives = 25/42 (59%)
 Frame = +2

Query: 651 LLDLIKGMKYLHHREFIHGRLKSRNCVVDGRFVLKVTDYGFN 692
           +  L   ++Y H+R+ IH  +K  N ++  +  LK+ D+G++
Sbjct: 185 IYQLSSALEYCHYRKVIHRDIKPENLLLGLKGDLKIADFGWS 310
>14477
          Length = 493

 Score = 37.0 bits (84), Expect = 0.042,   Method: Composition-based stats.
 Identities = 27/107 (25%), Positives = 49/107 (45%)
 Frame = -1

Query: 586 SIKSSASDVFEMMKDLRHENVNPLLGFFYDSGMFAIVSEFCSRRSLEDILTNDDVKLDWM 645
           S++S      E+MK + H ++  L+G      M  +V E      L   L  +     W 
Sbjct: 361 SVQSELIKEAEVMKKMDHMHIVRLIGLCEGETMM-LVLELAKLGPLNKFLPKNKHLPLWN 185

Query: 646 FKSSLLLDLIKGMKYLHHREFIHGRLKSRNCVVDGRFVLKVTDYGFN 692
               L+  + +GM+YL   +F+H  L +RN ++      K++D+G +
Sbjct: 184 ILE-LMWQVSQGMEYLEANKFVHRDLAARNILLCDEHFAKISDFGMS 47
>27546
          Length = 426

 Score = 35.8 bits (81), Expect = 0.11,   Method: Composition-based stats.
 Identities = 15/48 (31%), Positives = 25/48 (52%)
 Frame = -1

Query: 644 WMFKSSLLLDLIKGMKYLHHREFIHGRLKSRNCVVDGRFVLKVTDYGF 691
           W F+      + K ++YLH  +  H  LK  N ++  R  +K+ D+GF
Sbjct: 165 WFFQ------MAKALQYLHSHDIAHRDLKCENILLSKRLNVKIADFGF 40
>25550
          Length = 941

 Score = 35.0 bits (79), Expect = 0.18,   Method: Composition-based stats.
 Identities = 18/54 (33%), Positives = 31/54 (57%)
 Frame = +3

Query: 777 PEYAPAECLQLMKQCWAEASEQRPTFDEIFNQFKTFNKGKKTNIIDSMLRMLEQ 830
           P+  PA+   LM +CW    ++RPTF EI   +   N  +K++I + + + LE+
Sbjct: 105 PQGTPADVYILMLKCWQWDPKERPTFKEI--HYLLENMFEKSSISEEVEKELEK 260
>35671
          Length = 567

 Score = 33.9 bits (76), Expect = 0.42,   Method: Composition-based stats.
 Identities = 11/23 (47%), Positives = 17/23 (73%)
 Frame = -3

Query: 783 ECLQLMKQCWAEASEQRPTFDEI 805
           E  ++M QCW E+ E+RPTF ++
Sbjct: 523 EAYKVMLQCWTESREERPTFKKL 455
>00300
          Length = 2318

 Score = 33.1 bits (74), Expect = 0.57,   Method: Compositional matrix adjust.
 Identities = 24/125 (19%), Positives = 52/125 (41%), Gaps = 2/125 (1%)
 Frame = -1

Query: 568  GDWVWLK--KFPPGDFGDIKSIKSSASDVFEMMKDLRHENVNPLLGFFYDSGMFAIVSEF 625
            G+ + LK  KF P D   ++ +     D  ++ + ++HEN+    G         +  E+
Sbjct: 1583 GELMALKEMKFQPNDLQQLREM----CDEIKIFEGIQHENLVKYYGVEVHKDEMLMFMEY 1416

Query: 626  CSRRSLEDILTNDDVKLDWMFKSSLLLDLIKGMKYLHHREFIHGRLKSRNCVVDGRFVLK 685
            C   ++E+      + L          +++  + +LH    +H  +K  N  +     +K
Sbjct: 1415 CDTGTIEEAAK---MGLPEYLIRRYTREIVLAVNHLHENSIVHRDIKGANIFLTSNGHVK 1245

Query: 686  VTDYG 690
            + D+G
Sbjct: 1244 LGDFG 1230
>32264
          Length = 287

 Score = 32.3 bits (72), Expect = 1.0,   Method: Composition-based stats.
 Identities = 14/40 (35%), Positives = 21/40 (52%)
 Frame = +1

Query: 771 YRPVVSPEYAPAECLQLMKQCWAEASEQRPTFDEIFNQFK 810
           YR   +P+  P    +LM +CW    E+RP F E++   K
Sbjct: 13  YRLQQNPQ-TPDSVYKLMLRCWEYVPEKRPHFKELYTSLK 129
>07933
          Length = 728

 Score = 32.3 bits (72), Expect = 1.1,   Method: Composition-based stats.
 Identities = 11/29 (37%), Positives = 15/29 (51%)
 Frame = +3

Query: 777 PEYAPAECLQLMKQCWAEASEQRPTFDEI 805
           P Y P     +M QCW+     RPTF ++
Sbjct: 3   PNYCPNLLYNIMMQCWSAEPSARPTFHKL 89
>19094
          Length = 898

 Score = 32.0 bits (71), Expect = 1.6,   Method: Composition-based stats.
 Identities = 23/96 (23%), Positives = 41/96 (42%)
 Frame = +1

Query: 648 SSLLLDLIKGMKYLHHREFIHGRLKSRNCVVDGRFVLKVTDYGFNDIXXXXXXXXXXXXX 707
           +++L   +KG+ YLH R  IH  +K+ N +++     K+ D+G                 
Sbjct: 67  ATILYYTLKGL*YLHSRRKIHRDIKAGNILLNNEGHAKLADFGVAG-QLTDTMAKRNTVI 243

Query: 708 XXXXWTAPELLRAPGGIRLGSFAGDVYSFAIIMQEV 743
               W APE+++  G         D++S  I   E+
Sbjct: 244 GTPYWMAPEVIQEIG----YDCVADIWSLGITALEM 339
>04862
          Length = 938

 Score = 30.8 bits (68), Expect = 3.3,   Method: Composition-based stats.
 Identities = 19/54 (35%), Positives = 32/54 (59%), Gaps = 3/54 (5%)
 Frame = +1

Query: 343 NQVSPLFGTIYNSIYFIAQAMNNAM---KKNGRASAASLVQHSRNMQFYGFNQL 393
           ++++ LF   YN+I    +  +  +   K+NG++  ASLVQ S  +QFY  +QL
Sbjct: 157 DRIAALFLFSYNAIAGEREENSGRVLHDKRNGKSKWASLVQTSSFLQFYKSSQL 318
>27287
          Length = 514

 Score = 30.8 bits (68), Expect = 3.4,   Method: Compositional matrix adjust.
 Identities = 11/33 (33%), Positives = 16/33 (48%)
 Frame = -2

Query: 777 PEYAPAECLQLMKQCWAEASEQRPTFDEIFNQF 809
           P YA +E   +M  CW E    RP+F  +  + 
Sbjct: 504 PPYASSEMFGIMHSCWQEDPNDRPSFSRLVQEL 406
>13066
          Length = 551

 Score = 30.8 bits (68), Expect = 3.4,   Method: Compositional matrix adjust.
 Identities = 12/38 (31%), Positives = 20/38 (52%)
 Frame = +3

Query: 654 LIKGMKYLHHREFIHGRLKSRNCVVDGRFVLKVTDYGF 691
           +   + YLH  +  H  LK  N ++   F +K+ D+GF
Sbjct: 303 MTTALNYLHSYDVAHRDLKCENILLSSHFNVKLADFGF 416
>03240
          Length = 1683

 Score = 30.4 bits (67), Expect = 4.2,   Method: Compositional matrix adjust.
 Identities = 22/96 (22%), Positives = 45/96 (46%)
 Frame = -3

Query: 596  EMMKDLRHENVNPLLGFFYDSGMFAIVSEFCSRRSLEDILTNDDVKLDWMFKSSLLLDLI 655
            +++ +  +E V  L   F D      V ++     L  +L   ++ LD       + +L+
Sbjct: 1135 DILAEADNEWVVKLYYSFQDHNYLYFVMDYVPGGDLMGLLIRMEI-LDEPLARFYVAELV 959

Query: 656  KGMKYLHHREFIHGRLKSRNCVVDGRFVLKVTDYGF 691
            + ++ +H   FIH  +K  N ++D    +K+TD+G 
Sbjct: 958  QAIESVHRMGFIHRDIKPDNILIDRNGHIKLTDFGL 851
>37602
          Length = 804

 Score = 30.0 bits (66), Expect = 5.6,   Method: Compositional matrix adjust.
 Identities = 24/95 (25%), Positives = 43/95 (45%), Gaps = 10/95 (10%)
 Frame = -1

Query: 605 NVNPLLGFFYDSGM----FAIVSEFCSRRSLEDI------LTNDDVKLDWMFKSSLLLDL 654
           N+   +G+F DS +      I  E+C   S++DI      LT   +         +  + 
Sbjct: 345 NIQTFVGYF-DSYLRREKLWIAMEYCGGGSMQDIYHVTGPLTEPQIAF-------VCRET 190

Query: 655 IKGMKYLHHREFIHGRLKSRNCVVDGRFVLKVTDY 689
           +KG+ YLH R  +H  +K  N ++     +K+ D+
Sbjct: 189 LKGLHYLHRRGKMHRDIKGANILLTEEGDVKLADF 85
>04138
          Length = 800

 Score = 29.6 bits (65), Expect = 7.9,   Method: Compositional matrix adjust.
 Identities = 10/34 (29%), Positives = 21/34 (61%)
 Frame = +1

Query: 658 MKYLHHREFIHGRLKSRNCVVDGRFVLKVTDYGF 691
           + Y+H  + +H  +K+ N ++  + VLK+ D+G 
Sbjct: 52  LYYIHRNKILHRDMKAANILITKQGVLKLADFGL 153
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|27777691|ref|NP_766491.1| mannosidase 2, alpha 2 [Mus
musculus]
         (827 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

35221                                                                 120   9e-53
04147                                                                  29   9.3  
>35221
          Length = 609

 Score =  120 bits (300), Expect(2) = 9e-53,   Method: Compositional matrix adjust.
 Identities = 52/106 (49%), Positives = 70/106 (66%)
 Frame = +1

Query: 196 LNSMVSKLQEDPRRRFLWAEVSFFAKWWDNISAQKRAAVRRLVGNGQLEIATGGWVMPDE 255
           L+  V KL E    RF+W+E +F ++W+   S  ++ A++R +  GQLE+ TGGWVM +E
Sbjct: 7   LSGAVQKLAEHSSWRFIWSETAFLSRWYKEASDDQKQALKRAISRGQLEVVTGGWVMTEE 186

Query: 256 ANSHYFALVDQLIEGHQWLERNLGATPRSGWAVDPFGHSSTMPYLL 301
             +HY A++DQL EGH WL   LG  P   W+VDPFGHS TM YLL
Sbjct: 187 GCAHYAAMLDQLTEGHLWLTEELGIEPNVSWSVDPFGHSPTMAYLL 324

 Score =  106 bits (265), Expect(2) = 9e-53,   Method: Compositional matrix adjust.
 Identities = 42/69 (60%), Positives = 55/69 (79%)
 Frame = +3

Query: 304 ANLTSMLIQRVHYAIKKHFAATHSLEFMWRQMWDSDSSTDIFCHMMPFYSYDVPHTCGPD 363
           + ++ M+IQRVH+AIK++ A    LEF WRQ+WD + STDI CHMMPF SY +P++CGPD
Sbjct: 330 SGVSKMVIQRVHFAIKRYLANAQRLEFDWRQVWDENGSTDISCHMMPFLSYAIPYSCGPD 509

Query: 364 PKICCQFDF 372
           P +CCQFDF
Sbjct: 510 PHVCCQFDF 536
>04147
          Length = 434

 Score = 28.9 bits (63), Expect = 9.3,   Method: Composition-based stats.
 Identities = 12/36 (33%), Positives = 18/36 (50%)
 Frame = +2

Query: 326 HSLEFMWRQMWDSDSSTDIFCHMMPFYSYDVPHTCG 361
           HS  F +R +    ++T I CH +  Y+Y    TC 
Sbjct: 317 HSKSFQFRDLSLLTATTQICCHKISIYNYTEESTCA 424
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|116256491|ref|NP_733924.2| ankyrin 3, epithelial
isoform a [Mus musculus]
         (1726 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

19166                                                                 205   1e-52
09292                                                                 159   7e-39
06253                                                                 139   1e-32
13462                                                                 113   6e-25
14005                                                                 112   1e-24
11295                                                                 111   3e-24
02114                                                                  99   6e-24
05924                                                                 101   3e-21
00540                                                                  83   1e-15
02055                                                                  81   4e-15
25470                                                                  75   2e-13
08473                                                                  75   3e-13
11861                                                                  70   1e-11
34789                                                                  68   4e-11
20792                                                                  66   1e-10
28494                                                                  65   2e-10
20884                                                                  44   1e-09
28113                                                                  62   3e-09
09180                                                                  60   7e-09
20036                                                                  60   7e-09
21532                                                                  60   9e-09
35952                                                                  45   2e-08
12417                                                                  59   2e-08
16561                                                                  57   5e-08
38834                                                                  57   6e-08
15772                                                                  57   9e-08
28691                                                                  55   3e-07
30463                                                                  55   3e-07
21751                                                                  39   5e-07
22269                                                                  37   6e-06
15359                                                                  50   9e-06
33144                                                                  50   1e-05
17893                                                                  50   1e-05
30978                                                                  49   2e-05
27067                                                                  47   8e-05
13900                                                                  45   3e-04
05396                                                                  44   4e-04
25464                                                                  44   5e-04
27108                                                                  44   6e-04
22305                                                                  44   7e-04
20121                                                                  44   8e-04
30217                                                                  43   0.001
03590                                                                  42   0.001
36879                                                                  43   0.001
08755                                                                  40   0.011
04513                                                                  39   0.027
09214                                                                  37   0.059
20757                                                                  37   0.067
18216                                                                  37   0.092
02351                                                                  36   0.10 
37115                                                                  36   0.13 
33484                                                                  35   0.24 
36917                                                                  33   0.90 
35959                                                                  33   1.5  
28671                                                                  32   2.1  
20955                                                                  32   2.4  
07652                                                                  31   4.6  
28491                                                                  30   6.3  
>19166
          Length = 447

 Score =  205 bits (522), Expect = 1e-52,   Method: Compositional matrix adjust.
 Identities = 95/149 (63%), Positives = 124/149 (83%)
 Frame = +1

Query: 364 KVAKVLLDKKASPNAKALNGFTPLHIACKKNRIRVMELLLKHGASIQAVTESGLTPIHVA 423
           K AK+LLD+K  PN++ALNGFTPLHIACKKNRI+V+ELLLK+GASI A TESGLTP+HV+
Sbjct: 1   KTAKLLLDRKCEPNSRALNGFTPLHIACKKNRIKVVELLLKYGASIDATTESGLTPLHVS 180

Query: 424 AFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQ 483
           +FMGH+NIV  L+ H A P+T  VRGET+LH+AAR+ Q +++R L+++GA V+A+A++ Q
Sbjct: 181 SFMGHMNIVIYLIQHNAYPDTPTVRGETSLHLAARANQTDIIRILLRNGAAVDARAREQQ 360

Query: 484 TPLHISARLGKADIVQQLLQQGASPNAAT 512
           TPLHI++RLG  D V  LLQ GAS +A T
Sbjct: 361 TPLHIASRLGNVDNVVLLLQHGASADATT 447

 Score =  119 bits (297), Expect = 1e-26,   Method: Compositional matrix adjust.
 Identities = 61/149 (40%), Positives = 92/149 (61%)
 Frame = +1

Query: 595 KVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATSLLEYGADANAVTRQGIASVHLA 654
           K A LLLD+   P++ A NG+TPLHIA KKN++ +   LL+YGA  +A T  G+  +H++
Sbjct: 1   KTAKLLLDRKCEPNSRALNGFTPLHIACKKNRIKVVELLLKYGASIDATTESGLTPLHVS 180

Query: 655 AQEGHVDMVSLLLSRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGY 714
           +  GH+++V  L+  NA  +     G T LHLAA+ ++ ++  +L+  GA VDA+ +   
Sbjct: 181 SFMGHMNIVIYLIQHNAYPDTPTVRGETSLHLAARANQTDIIRILLRNGAAVDARAREQQ 360

Query: 715 TPLHVGCHYGNIKIVNFLLQHSAKVNAKT 743
           TPLH+    GN+  V  LLQH A  +A T
Sbjct: 361 TPLHIASRLGNVDNVVLLLQHGASADATT 447

 Score =  106 bits (265), Expect = 7e-23,   Method: Compositional matrix adjust.
 Identities = 56/144 (38%), Positives = 84/144 (58%)
 Frame = +1

Query: 501 LLQQGASPNAATTSGYTPLHLAAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGK 560
           LL +   PN+   +G+TPLH+A ++    V   LL +GAS+  TT+ G TPLHV++  G 
Sbjct: 16  LLDRKCEPNSRALNGFTPLHIACKKNRIKVVELLLKYGASIDATTESGLTPLHVSSFMGH 195

Query: 561 LEVASLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHI 620
           + +   L+Q +A PD     G T LH+AA  +   +  +LL  GA+  A A+   TPLHI
Sbjct: 196 MNIVIYLIQHNAYPDTPTVRGETSLHLAARANQTDIIRILLRNGAAVDARAREQQTPLHI 375

Query: 621 AAKKNQMDIATSLLEYGADANAVT 644
           A++   +D    LL++GA A+A T
Sbjct: 376 ASRLGNVDNVVLLLQHGASADATT 447

 Score =  103 bits (256), Expect = 8e-22,   Method: Compositional matrix adjust.
 Identities = 51/148 (34%), Positives = 88/148 (59%)
 Frame = +1

Query: 298 QVVEMLLDRSAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVA 357
           +  ++LLDR     S+  NG +PLH+A + + +  V+LLL++   +D  T   LT LHV+
Sbjct: 1   KTAKLLLDRKCEPNSRALNGFTPLHIACKKNRIKVVELLLKYGASIDATTESGLTPLHVS 180

Query: 358 AHCGHYKVAKVLLDKKASPNAKALNGFTPLHIACKKNRIRVMELLLKHGASIQAVTESGL 417
           +  GH  +   L+   A P+   + G T LH+A + N+  ++ +LL++GA++ A      
Sbjct: 181 SFMGHMNIVIYLIQHNAYPDTPTVRGETSLHLAARANQTDIIRILLRNGAAVDARAREQQ 360

Query: 418 TPIHVAAFMGHVNIVSQLMHHGASPNTT 445
           TP+H+A+ +G+V+ V  L+ HGAS + T
Sbjct: 361 TPLHIASRLGNVDNVVLLLQHGASADAT 444

 Score =  103 bits (256), Expect = 9e-22,   Method: Compositional matrix adjust.
 Identities = 54/142 (38%), Positives = 83/142 (58%)
 Frame = +1

Query: 435 LMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGK 494
           L+     PN+  + G T LH+A +  + +VV  L++ GA ++A  +   TPLH+S+ +G 
Sbjct: 16  LLDRKCEPNSRALNGFTPLHIACKKNRIKVVELLLKYGASIDATTESGLTPLHVSSFMGH 195

Query: 495 ADIVQQLLQQGASPNAATTSGYTPLHLAAREGHEDVAAFLLDHGASLSITTKKGFTPLHV 554
            +IV  L+Q  A P+  T  G T LHLAAR    D+   LL +GA++    ++  TPLH+
Sbjct: 196 MNIVIYLIQHNAYPDTPTVRGETSLHLAARANQTDIIRILLRNGAAVDARAREQQTPLHI 375

Query: 555 AAKYGKLEVASLLLQKSASPDA 576
           A++ G ++   LLLQ  AS DA
Sbjct: 376 ASRLGNVDNVVLLLQHGASADA 441

 Score =  100 bits (250), Expect = 4e-21,   Method: Compositional matrix adjust.
 Identities = 58/146 (39%), Positives = 87/146 (59%)
 Frame = +1

Query: 268 KLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRSAPILSKTKNGLSPLHMATQG 327
           KLLLDR  + +++  +G TPLH   +    +VVE+LL   A I + T++GL+PLH+++  
Sbjct: 10  KLLLDRKCEPNSRALNGFTPLHIACKKNRIKVVELLLKYGASIDATTESGLTPLHVSSFM 189

Query: 328 DHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKASPNAKALNGFTPL 387
            H+N V  L+QHN   D  T    T+LH+AA      + ++LL   A+ +A+A    TPL
Sbjct: 190 GHMNIVIYLIQHNAYPDTPTVRGETSLHLAARANQTDIIRILLRNGAAVDARAREQQTPL 369

Query: 388 HIACKKNRIRVMELLLKHGASIQAVT 413
           HIA +   +  + LLL+HGAS  A T
Sbjct: 370 HIASRLGNVDNVVLLLQHGASADATT 447

 Score =  100 bits (248), Expect = 6e-21,   Method: Compositional matrix adjust.
 Identities = 57/144 (39%), Positives = 81/144 (56%)
 Frame = +1

Query: 531 AAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVASLLLQKSASPDAAGKSGLTPLHVAAH 590
           A  LLD     +     GFTPLH+A K  +++V  LLL+  AS DA  +SGLTPLHV++ 
Sbjct: 7   AKLLLDRKCEPNSRALNGFTPLHIACKKNRIKVVELLLKYGASIDATTESGLTPLHVSSF 186

Query: 591 YDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATSLLEYGADANAVTRQGIAS 650
             +  + + L+   A P      G T LH+AA+ NQ DI   LL  GA  +A  R+    
Sbjct: 187 MGHMNIVIYLIQHNAYPDTPTVRGETSLHLAARANQTDIIRILLRNGAAVDARAREQQTP 366

Query: 651 VHLAAQEGHVDMVSLLLSRNANVN 674
           +H+A++ G+VD V LLL   A+ +
Sbjct: 367 LHIASRLGNVDNVVLLLQHGASAD 438

 Score = 98.6 bits (244), Expect = 2e-20,   Method: Compositional matrix adjust.
 Identities = 55/131 (41%), Positives = 78/131 (59%)
 Frame = +1

Query: 665 LLLSRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYG 724
           LLL R    N    +G TPLH+A +++R+ V E+L+  GA +DA T+ G TPLHV    G
Sbjct: 13  LLLDRKCEPNSRALNGFTPLHIACKKNRIKVVELLLKYGASIDATTESGLTPLHVSSFMG 192

Query: 725 NIKIVNFLLQHSAKVNAKTKNGYTALHQAAQQGHTHIINVLLQNNASPNELTVNGNTALA 784
           ++ IV +L+QH+A  +  T  G T+LH AA+   T II +LL+N A+ +       T L 
Sbjct: 193 HMNIVIYLIQHNAYPDTPTVRGETSLHLAARANQTDIIRILLRNGAAVDARAREQQTPLH 372

Query: 785 IARRLGYISVV 795
           IA RLG +  V
Sbjct: 373 IASRLGNVDNV 405

 Score = 96.7 bits (239), Expect = 8e-20,   Method: Compositional matrix adjust.
 Identities = 62/178 (34%), Positives = 87/178 (48%)
 Frame = +1

Query: 104 EVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVRFLLDNGASQSLATEDGFTPLAVA 163
           +  K+L+      N+++ NGFTPL++A ++N ++VV  LL  GAS    TE G TPL V+
Sbjct: 1   KTAKLLLDRKCEPNSRALNGFTPLHIACKKNRIKVVELLLKYGASIDATTESGLTPLHVS 180

Query: 164 LQQGHDQVVSLLLENDTKGKVRLPALHIAARKDDTKAAALLLQNDTNADVESKSGFTPLH 223
              GH  +V                               L+Q++   D  +  G T LH
Sbjct: 181 SFMGHMNIV-----------------------------IYLIQHNAYPDTPTVRGETSLH 273

Query: 224 IAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRGNANMVKLLLDRGAKIDAKT 281
           +AA     ++  +LL   AAVD  AR   TPLH+AS+ GN + V LLL  GA  DA T
Sbjct: 274 LAARANQTDIIRILLRNGAAVDARAREQQTPLHIASRLGNVDNVVLLLQHGASADATT 447

 Score = 95.1 bits (235), Expect = 2e-19,   Method: Compositional matrix adjust.
 Identities = 51/147 (34%), Positives = 85/147 (57%)
 Frame = +1

Query: 463 EVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLA 522
           +  + L+    +  ++A +  TPLHI+ +  +  +V+ LL+ GAS +A T SG TPLH++
Sbjct: 1   KTAKLLLDRKCEPNSRALNGFTPLHIACKKNRIKVVELLLKYGASIDATTESGLTPLHVS 180

Query: 523 AREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVASLLLQKSASPDAAGKSGL 582
           +  GH ++  +L+ H A     T +G T LH+AA+  + ++  +LL+  A+ DA  +   
Sbjct: 181 SFMGHMNIVIYLIQHNAYPDTPTVRGETSLHLAARANQTDIIRILLRNGAAVDARAREQQ 360

Query: 583 TPLHVAAHYDNQKVALLLLDQGASPHA 609
           TPLH+A+   N    +LLL  GAS  A
Sbjct: 361 TPLHIASRLGNVDNVVLLLQHGASADA 441

 Score = 95.1 bits (235), Expect = 2e-19,   Method: Compositional matrix adjust.
 Identities = 55/149 (36%), Positives = 81/149 (54%)
 Frame = +1

Query: 199 KAAALLLQNDTNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVA 258
           K A LLL      +  + +GFTPLHIA     I V  LLL   A++D T  + +TPLHV+
Sbjct: 1   KTAKLLLDRKCEPNSRALNGFTPLHIACKKNRIKVVELLLKYGASIDATTESGLTPLHVS 180

Query: 259 SKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRSAPILSKTKNGL 318
           S  G+ N+V  L+   A  D  T  G T LH  AR+    ++ +LL   A + ++ +   
Sbjct: 181 SFMGHMNIVIYLIQHNAYPDTPTVRGETSLHLAARANQTDIIRILLRNGAAVDARAREQQ 360

Query: 319 SPLHMATQGDHLNCVQLLLQHNVPVDDVT 347
           +PLH+A++  +++ V LLLQH    D  T
Sbjct: 361 TPLHIASRLGNVDNVVLLLQHGASADATT 447

 Score = 94.0 bits (232), Expect = 5e-19,   Method: Compositional matrix adjust.
 Identities = 53/149 (35%), Positives = 84/149 (56%)
 Frame = +1

Query: 562 EVASLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIA 621
           + A LLL +   P++   +G TPLH+A   +  KV  LLL  GAS  A  ++G TPLH++
Sbjct: 1   KTAKLLLDRKCEPNSRALNGFTPLHIACKKNRIKVVELLLKYGASIDATTESGLTPLHVS 180

Query: 622 AKKNQMDIATSLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLSRNANVNLSNKSGL 681
           +    M+I   L+++ A  +  T +G  S+HLAA+    D++ +LL   A V+   +   
Sbjct: 181 SFMGHMNIVIYLIQHNAYPDTPTVRGETSLHLAARANQTDIIRILLRNGAAVDARAREQQ 360

Query: 682 TPLHLAAQEDRVNVAEVLVNQGAHVDAQT 710
           TPLH+A++   V+   +L+  GA  DA T
Sbjct: 361 TPLHIASRLGNVDNVVLLLQHGASADATT 447

 Score = 88.6 bits (218), Expect = 2e-17,   Method: Compositional matrix adjust.
 Identities = 53/145 (36%), Positives = 80/145 (55%)
 Frame = +1

Query: 234 ATLLLNRAAAVDFTARNDITPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGAR 293
           A LLL+R    +  A N  TPLH+A K+    +V+LLL  GA IDA T  GLTPLH  + 
Sbjct: 7   AKLLLDRKCEPNSRALNGFTPLHIACKKNRIKVVELLLKYGASIDATTESGLTPLHVSSF 186

Query: 294 SGHEQVVEMLLDRSAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTA 353
            GH  +V  L+  +A   + T  G + LH+A + +  + +++LL++   VD    +  T 
Sbjct: 187 MGHMNIVIYLIQHNAYPDTPTVRGETSLHLAARANQTDIIRILLRNGAAVDARAREQQTP 366

Query: 354 LHVAAHCGHYKVAKVLLDKKASPNA 378
           LH+A+  G+     +LL   AS +A
Sbjct: 367 LHIASRLGNVDNVVLLLQHGASADA 441

 Score = 80.9 bits (198), Expect = 4e-15,   Method: Compositional matrix adjust.
 Identities = 42/120 (35%), Positives = 69/120 (57%)
 Frame = +1

Query: 189 LHIAARKDDTKAAALLLQNDTNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFTA 248
           LHIA +K+  K   LLL+   + D  ++SG TPLH+++  G++N+   L+   A  D   
Sbjct: 70  LHIACKKNRIKVVELLLKYGASIDATTESGLTPLHVSSFMGHMNIVIYLIQHNAYPDTPT 249

Query: 249 RNDITPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRSA 308
               T LH+A++    +++++LL  GA +DA+ R+  TPLH  +R G+   V +LL   A
Sbjct: 250 VRGETSLHLAARANQTDIIRILLRNGAAVDARAREQQTPLHIASRLGNVDNVVLLLQHGA 429

 Score = 79.3 bits (194), Expect = 1e-14,   Method: Compositional matrix adjust.
 Identities = 44/123 (35%), Positives = 72/123 (58%)
 Frame = +1

Query: 56  NGLNALHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQAEVVKVLVTNGAN 115
           NG   LH+A K+  ++VV  LL+  A++DA T+ G T LH++S  G   +V  L+ + A 
Sbjct: 55  NGFTPLHIACKKNRIKVVELLLKYGASIDATTESGLTPLHVSSFMGHMNIVIYLIQHNAY 234

Query: 116 VNAQSQNGFTPLYMAAQENHLEVVRFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLL 175
            +  +  G T L++AA+ N  +++R LL NGA+      +  TPL +A + G+   V LL
Sbjct: 235 PDTPTVRGETSLHLAARANQTDIIRILLRNGAAVDARAREQQTPLHIASRLGNVDNVVLL 414

Query: 176 LEN 178
           L++
Sbjct: 415 LQH 423

 Score = 78.2 bits (191), Expect = 2e-14,   Method: Compositional matrix adjust.
 Identities = 39/110 (35%), Positives = 71/110 (64%)
 Frame = +1

Query: 44  IKNGVDVNICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQA 103
           +K G  ++   ++GL  LH++S  GH+ +V  L+Q  A  D  T +G T+LH+A+ A Q 
Sbjct: 118 LKYGASIDATTESGLTPLHVSSFMGHMNIVIYLIQHNAYPDTPTVRGETSLHLAARANQT 297

Query: 104 EVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVRFLLDNGASQSLAT 153
           +++++L+ NGA V+A+++   TPL++A++  +++ V  LL +GAS    T
Sbjct: 298 DIIRILLRNGAAVDARAREQQTPLHIASRLGNVDNVVLLLQHGASADATT 447

 Score = 76.6 bits (187), Expect = 8e-14,   Method: Compositional matrix adjust.
 Identities = 50/172 (29%), Positives = 84/172 (48%)
 Frame = +1

Query: 76  LLQREANVDAATKKGNTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENH 135
           LL R+   ++    G T LHIA    + +VV++L+  GA+++A +++G TPL++++   H
Sbjct: 16  LLDRKCEPNSRALNGFTPLHIACKKNRIKVVELLLKYGASIDATTESGLTPLHVSSFMGH 195

Query: 136 LEVVRFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLLENDTKGKVRLPALHIAARK 195
           + +V +L+ + A     T  G T                             +LH+AAR 
Sbjct: 196 MNIVIYLIQHNAYPDTPTVRGET-----------------------------SLHLAARA 288

Query: 196 DDTKAAALLLQNDTNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFT 247
           + T    +LL+N    D  ++   TPLHIA+  GN++   LLL   A+ D T
Sbjct: 289 NQTDIIRILLRNGAAVDARAREQQTPLHIASRLGNVDNVVLLLQHGASADAT 444

 Score = 75.1 bits (183), Expect = 2e-13,   Method: Compositional matrix adjust.
 Identities = 36/103 (34%), Positives = 64/103 (62%)
 Frame = +1

Query: 696 AEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTALHQAAQ 755
           A++L+++    +++   G+TPLH+ C    IK+V  LL++ A ++A T++G T LH ++ 
Sbjct: 7   AKLLLDRKCEPNSRALNGFTPLHIACKKNRIKVVELLLKYGASIDATTESGLTPLHVSSF 186

Query: 756 QGHTHIINVLLQNNASPNELTVNGNTALAIARRLGYISVVDTL 798
            GH +I+  L+Q+NA P+  TV G T+L +A R     ++  L
Sbjct: 187 MGHMNIVIYLIQHNAYPDTPTVRGETSLHLAARANQTDIIRIL 315

 Score = 44.7 bits (104), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 26/86 (30%), Positives = 47/86 (54%)
 Frame = +1

Query: 35  GHLEKALDYIKNGVDVNICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKGNTAL 94
           GH+   +  I++    +     G  +LHLA++    +++  LL+  A VDA  ++  T L
Sbjct: 190 GHMNIVIYLIQHNAYPDTPTVRGETSLHLAARANQTDIIRILLRNGAAVDARAREQQTPL 369

Query: 95  HIASLAGQAEVVKVLVTNGANVNAQS 120
           HIAS  G  + V +L+ +GA+ +A +
Sbjct: 370 HIASRLGNVDNVVLLLQHGASADATT 447

 Score = 32.3 bits (72), Expect = 1.8,   Method: Compositional matrix adjust.
 Identities = 21/57 (36%), Positives = 31/57 (54%)
 Frame = +1

Query: 31  AARAGHLEKALDYIKNGVDVNICNQNGLNALHLASKEGHVEVVSELLQREANVDAAT 87
           AARA   +     ++NG  V+   +     LH+AS+ G+V+ V  LLQ  A+ DA T
Sbjct: 277 AARANQTDIIRILLRNGAAVDARAREQQTPLHIASRLGNVDNVVLLLQHGASADATT 447
>09292
          Length = 1486

 Score =  159 bits (403), Expect = 7e-39,   Method: Compositional matrix adjust.
 Identities = 111/378 (29%), Positives = 186/378 (49%), Gaps = 7/378 (1%)
 Frame = -2

Query: 351  LTALHVAAHCGHYKVAKVLLDKKASPNAKALNGFTPLHIACKKNRIRVMELLLKHGASIQ 410
              ALH A      +     LD     + +  +  T LH  C    +++  +LLKH A + 
Sbjct: 1458 FCALHCAXQLQDVETLLAYLDIGMHVDTRDSHHETALHAVCYVGSVKMASVLLKHXADVN 1279

Query: 411  AVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQ 470
            A      TP+H+ A  GH+ +V +L+ HGA  N  +    T +  A      ++VRYL++
Sbjct: 1278 ARNNVDRTPLHIXAIEGHLGLVEELVRHGADFNAEDKDHLTPVFNACVKNDTDIVRYLLE 1099

Query: 471  DGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLAAREGHEDV 530
             GA+    A+    P+  + + G ++IVQ LL  GA+ N+   +  +PLH+A R G+ ++
Sbjct: 1098 SGARANTTAR----PIFHAVKYGYSEIVQLLLVHGAAVNSLPGTK-SPLHIACRNGNIEM 934

Query: 531  AAFLLDHGASLSITTKKGFTPLHVAAKY-GKLEVASLLLQKSASPDAAGKSGLTPLHVAA 589
            A  ++  GA+++   K G TPLH++ +     ++  LL++  A+      +   PLH+A 
Sbjct: 933  ARTVIIAGANVNAVDKDGNTPLHISVRAPSSAQLVRLLIRFGANVKWGNDNQQIPLHLAC 754

Query: 590  HYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATSLLEYGADANAVTRQGIA 649
             Y N + A LLL  G+  +  +   +TPLH A     +DI   +L+  +D N+   +  A
Sbjct: 753  LYSNLETARLLLHCGSCSNELSSKLWTPLHYAVIGGNVDIVRLVLQGSSDVNSPDGRNNA 574

Query: 650  SVHLAAQEGHVDMVSLLLSRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAH---- 705
             +HLA  +  + +   LL   ANVN+S  +G TPLH+A     + +  +L   GA+    
Sbjct: 573  PLHLACMKQCIGIARCLLRHGANVNVSGYNGRTPLHIAISHHNLELVLLLYMCGANDQLV 394

Query: 706  -VDAQTKMGYTPLHV-GC 721
              D      Y+  H+ GC
Sbjct: 393  DFDGNFPSCYSMCHIHGC 340

 Score =  154 bits (390), Expect = 2e-37,   Method: Compositional matrix adjust.
 Identities = 108/351 (30%), Positives = 178/351 (50%), Gaps = 2/351 (0%)
 Frame = -2

Query: 384  FTPLHIACKKNRIRVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPN 443
            F  LH A +   +  +   L  G  +        T +H   ++G V + S L+ H A  N
Sbjct: 1458 FCALHCAXQLQDVETLLAYLDIGMHVDTRDSHHETALHAVCYVGSVKMASVLLKHXADVN 1279

Query: 444  TTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQ 503
              N    T LH+ A  G   +V  LV+ GA   A+ KD  TP+  +      DIV+ LL+
Sbjct: 1278 ARNNVDRTPLHIXAIEGHLGLVEELVRHGADFNAEDKDHLTPVFNACVKNDTDIVRYLLE 1099

Query: 504  QGASPNAATTSGYTPLHLAAREGHEDVAAFLLDHGASL-SITTKKGFTPLHVAAKYGKLE 562
             GA  N  TT+   P+  A + G+ ++   LL HGA++ S+   K  +PLH+A + G +E
Sbjct: 1098 SGARAN--TTA--RPIFHAVKYGYSEIVQLLLVHGAAVNSLPGTK--SPLHIACRNGNIE 937

Query: 563  VASLLLQKSASPDAAGKSGLTPLHVAAHY-DNQKVALLLLDQGASPHAAAKNGYTPLHIA 621
            +A  ++   A+ +A  K G TPLH++     + ++  LL+  GA+      N   PLH+A
Sbjct: 936  MARTVIIAGANVNAVDKDGNTPLHISVRAPSSAQLVRLLIRFGANVKWGNDNQQIPLHLA 757

Query: 622  AKKNQMDIATSLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLSRNANVNLSNKSGL 681
               + ++ A  LL  G+ +N ++ +    +H A   G+VD+V L+L  +++VN  +    
Sbjct: 756  CLYSNLETARLLLHCGSCSNELSSKLWTPLHYAVIGGNVDIVRLVLQGSSDVNSPDGRNN 577

Query: 682  TPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFL 732
             PLHLA  +  + +A  L+  GA+V+     G TPLH+   + N+++V  L
Sbjct: 576  APLHLACMKQCIGIARCLLRHGANVNVSGYNGRTPLHIAISHHNLELVLLL 424

 Score =  139 bits (351), Expect = 7e-33,   Method: Compositional matrix adjust.
 Identities = 98/364 (26%), Positives = 177/364 (48%), Gaps = 1/364 (0%)
 Frame = -2

Query: 255  LHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRSAPILSKT 314
            LH A +  +   +   LD G  +D +     T LH     G  ++  +LL   A + ++ 
Sbjct: 1449 LHCAXQLQDVETLLAYLDIGMHVDTRDSHHETALHAVCYVGSVKMASVLLKHXADVNARN 1270

Query: 315  KNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKA 374
                +PLH+     HL  V+ L++H    +    D+LT +  A       + + LL+  A
Sbjct: 1269 NVDRTPLHIXAIEGHLGLVEELVRHGADFNAEDKDHLTPVFNACVKNDTDIVRYLLESGA 1090

Query: 375  SPNAKALNGFTPLHIACKKNRIRVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQ 434
              N  A     P+  A K     +++LLL HGA++ ++  +  +P+H+A   G++ +   
Sbjct: 1089 RANTTA----RPIFHAVKYGYSEIVQLLLVHGAAVNSLPGTK-SPLHIACRNGNIEMART 925

Query: 435  LMHHGASPNTTNVRGETALHMAARS-GQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLG 493
            ++  GA+ N  +  G T LH++ R+   A++VR L++ GA V+    + Q PLH++    
Sbjct: 924  VIIAGANVNAVDKDGNTPLHISVRAPSSAQLVRLLIRFGANVKWGNDNQQIPLHLACLYS 745

Query: 494  KADIVQQLLQQGASPNAATTSGYTPLHLAAREGHEDVAAFLLDHGASLSITTKKGFTPLH 553
              +  + LL  G+  N  ++  +TPLH A   G+ D+   +L   + ++    +   PLH
Sbjct: 744  NLETARLLLHCGSCSNELSSKLWTPLHYAVIGGNVDIVRLVLQGSSDVNSPDGRNNAPLH 565

Query: 554  VAAKYGKLEVASLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKN 613
            +A     + +A  LL+  A+ + +G +G TPLH+A  + N ++ LLL   GA+      +
Sbjct: 564  LACMKQCIGIARCLLRHGANVNVSGYNGRTPLHIAISHHNLELVLLLYMCGANDQLVDFD 385

Query: 614  GYTP 617
            G  P
Sbjct: 384  GNFP 373

 Score =  138 bits (348), Expect = 2e-32,   Method: Compositional matrix adjust.
 Identities = 111/391 (28%), Positives = 179/391 (45%), Gaps = 1/391 (0%)
 Frame = -2

Query: 60   ALHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQAEVVKVLVTNGANVNAQ 119
            ALH A +   VE +   L    +VD       TALH     G  ++  VL+ + A+VNA+
Sbjct: 1452 ALHCAXQLQDVETLLAYLDIGMHVDTRDSHHETALHAVCYVGSVKMASVLLKHXADVNAR 1273

Query: 120  SQNGFTPLYMAAQENHLEVVRFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLLEND 179
            +    TPL++ A E HL +V  L+ +GA  +   +D  TP+  A  +    +V  LLE+ 
Sbjct: 1272 NNVDRTPLHIXAIEGHLGLVEELVRHGADFNAEDKDHLTPVFNACVKNDTDIVRYLLES- 1096

Query: 180  TKGKVRLPALHIAARKDDTKAAALLLQNDTNADVESKSGFTPLHIAAHYGNINVATLLLN 239
                         AR + T                      P+  A  YG   +  LLL 
Sbjct: 1095 ------------GARANTTA--------------------RPIFHAVKYGYSEIVQLLLV 1012

Query: 240  RAAAVDFTARNDITPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARS-GHEQ 298
              AAV+ +     +PLH+A + GN  M + ++  GA ++A  +DG TPLH   R+    Q
Sbjct: 1011 HGAAVN-SLPGTKSPLHIACRNGNIEMARTVIIAGANVNAVDKDGNTPLHISVRAPSSAQ 835

Query: 299  VVEMLLDRSAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAA 358
            +V +L+   A +     N   PLH+A    +L   +LLL      +++++   T LH A 
Sbjct: 834  LVRLLIRFGANVKWGNDNQQIPLHLACLYSNLETARLLLHCGSCSNELSSKLWTPLHYAV 655

Query: 359  HCGHYKVAKVLLDKKASPNAKALNGFTPLHIACKKNRIRVMELLLKHGASIQAVTESGLT 418
              G+  + +++L   +  N+       PLH+AC K  I +   LL+HGA++     +G T
Sbjct: 654  IGGNVDIVRLVLQGSSDVNSPDGRNNAPLHLACMKQCIGIARCLLRHGANVNVSGYNGRT 475

Query: 419  PIHVAAFMGHVNIVSQLMHHGASPNTTNVRG 449
            P+H+A    ++ +V  L   GA+    +  G
Sbjct: 474  PLHIAISHHNLELVLLLYMCGANDQLVDFDG 382

 Score =  135 bits (341), Expect = 1e-31,   Method: Compositional matrix adjust.
 Identities = 103/367 (28%), Positives = 173/367 (47%), Gaps = 1/367 (0%)
 Frame = -2

Query: 415  SGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQ 474
            +    +H A  +  V  +   +  G   +T +   ETALH     G  ++   L++  A 
Sbjct: 1464 ASFCALHCAXQLQDVETLLAYLDIGMHVDTRDSHHETALHAVCYVGSVKMASVLLKHXAD 1285

Query: 475  VEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLAAREGHEDVAAFL 534
            V A+   D+TPLHI A  G   +V++L++ GA  NA      TP+  A  +   D+  +L
Sbjct: 1284 VNARNNVDRTPLHIXAIEGHLGLVEELVRHGADFNAEDKDHLTPVFNACVKNDTDIVRYL 1105

Query: 535  LDHGASLSITTKKGFTPLHVAAKYGKLEVASLLLQKSASPDAAGKSGLTPLHVAAHYDNQ 594
            L+ GA  + T +    P+  A KYG  E+  LLL   A+ ++   +  +PLH+A    N 
Sbjct: 1104 LESGARANTTAR----PIFHAVKYGYSEIVQLLLVHGAAVNSLPGTK-SPLHIACRNGNI 940

Query: 595  KVALLLLDQGASPHAAAKNGYTPLHIAAKK-NQMDIATSLLEYGADANAVTRQGIASVHL 653
            ++A  ++  GA+ +A  K+G TPLHI+ +  +   +   L+ +GA+           +HL
Sbjct: 939  EMARTVIIAGANVNAVDKDGNTPLHISVRAPSSAQLVRLLIRFGANVKWGNDNQQIPLHL 760

Query: 654  AAQEGHVDMVSLLLSRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMG 713
            A    +++   LLL   +  N  +    TPLH A     V++  +++   + V++     
Sbjct: 759  ACLYSNLETARLLLHCGSCSNELSSKLWTPLHYAVIGGNVDIVRLVLQGSSDVNSPDGRN 580

Query: 714  YTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTALHQAAQQGHTHIINVLLQNNASPN 773
              PLH+ C    I I   LL+H A VN    NG T LH A    +  ++ +L    A+  
Sbjct: 579  NAPLHLACMKQCIGIARCLLRHGANVNVSGYNGRTPLHIAISHHNLELVLLLYMCGANDQ 400

Query: 774  ELTVNGN 780
             +  +GN
Sbjct: 399  LVDFDGN 379

 Score =  132 bits (332), Expect = 1e-30,   Method: Compositional matrix adjust.
 Identities = 98/337 (29%), Positives = 156/337 (46%), Gaps = 1/337 (0%)
 Frame = -2

Query: 451  TALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNA 510
             ALH A +    E +   +  G  V+ +    +T LH    +G   +   LL+  A  NA
Sbjct: 1455 CALHCAXQLQDVETLLAYLDIGMHVDTRDSHHETALHAVCYVGSVKMASVLLKHXADVNA 1276

Query: 511  ATTSGYTPLHLAAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVASLLLQK 570
                  TPLH+ A EGH  +   L+ HGA  +   K   TP+  A      ++   LL+ 
Sbjct: 1275 RNNVDRTPLHIXAIEGHLGLVEELVRHGADFNAEDKDHLTPVFNACVKNDTDIVRYLLES 1096

Query: 571  SASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIA 630
             A  +   +    P+  A  Y   ++  LLL  GA+ ++      +PLHIA +   +++A
Sbjct: 1095 GARANTTAR----PIFHAVKYGYSEIVQLLLVHGAAVNSLPGTK-SPLHIACRNGNIEMA 931

Query: 631  TSLLEYGADANAVTRQGIASVHLAAQE-GHVDMVSLLLSRNANVNLSNKSGLTPLHLAAQ 689
             +++  GA+ NAV + G   +H++ +      +V LL+   ANV   N +   PLHLA  
Sbjct: 930  RTVIIAGANVNAVDKDGNTPLHISVRAPSSAQLVRLLIRFGANVKWGNDNQQIPLHLACL 751

Query: 690  EDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTA 749
               +  A +L++ G+  +  +   +TPLH     GN+ IV  +LQ S+ VN+        
Sbjct: 750  YSNLETARLLLHCGSCSNELSSKLWTPLHYAVIGGNVDIVRLVLQGSSDVNSPDGRNNAP 571

Query: 750  LHQAAQQGHTHIINVLLQNNASPNELTVNGNTALAIA 786
            LH A  +    I   LL++ A+ N    NG T L IA
Sbjct: 570  LHLACMKQCIGIARCLLRHGANVNVSGYNGRTPLHIA 460

 Score =  131 bits (330), Expect = 2e-30,   Method: Compositional matrix adjust.
 Identities = 109/388 (28%), Positives = 177/388 (45%), Gaps = 5/388 (1%)
 Frame = -2

Query: 37   LEKALDYIKNGVDVNICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKGNTALHI 96
            +E  L Y+  G+ V+  + +   ALH     G V++ S LL+  A+V+A      T LHI
Sbjct: 1422 VETLLAYLDIGMHVDTRDSHHETALHAVCYVGSVKMASVLLKHXADVNARNNVDRTPLHI 1243

Query: 97   ASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVRFLLDNGASQSLATEDG 156
             ++ G   +V+ LV +GA+ NA+ ++  TP++ A  +N  ++VR+LL++GA  +      
Sbjct: 1242 XAIEGHLGLVEELVRHGADFNAEDKDHLTPVFNACVKNDTDIVRYLLESGARANTTAR-- 1069

Query: 157  FTPLAVALQQGHDQVVSLLLENDTKGKVRLPA----LHIAARKDDTKAAALLLQNDTNAD 212
              P+  A++ G+ ++V LLL +       LP     LHIA R  + + A  ++    N +
Sbjct: 1068 --PIFHAVKYGYSEIVQLLLVHGAAVN-SLPGTKSPLHIACRNGNIEMARTVIIAGANVN 898

Query: 213  VESKSGFTPLHIAAHY-GNINVATLLLNRAAAVDFTARNDITPLHVASKRGNANMVKLLL 271
               K G TPLHI+     +  +  LL+   A V +   N   PLH+A    N    +LLL
Sbjct: 897  AVDKDGNTPLHISVRAPSSAQLVRLLIRFGANVKWGNDNQQIPLHLACLYSNLETARLLL 718

Query: 272  DRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRSAPILSKTKNGLSPLHMATQGDHLN 331
              G+  +  +    TPLH     G+  +V ++L  S+ + S      +PLH+A     + 
Sbjct: 717  HCGSCSNELSSKLWTPLHYAVIGGNVDIVRLVLQGSSDVNSPDGRNNAPLHLACMKQCIG 538

Query: 332  CVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKASPNAKALNGFTPLHIAC 391
              + LL+H                                  A+ N    NG TPLHIA 
Sbjct: 537  IARCLLRHG---------------------------------ANVNVSGYNGRTPLHIAI 457

Query: 392  KKNRIRVMELLLKHGASIQAVTESGLTP 419
              + + ++ LL   GA+ Q V   G  P
Sbjct: 456  SHHNLELVLLLYMCGANDQLVDFDGNFP 373

 Score = 97.8 bits (242), Expect = 3e-20,   Method: Compositional matrix adjust.
 Identities = 84/304 (27%), Positives = 131/304 (43%), Gaps = 31/304 (10%)
 Frame = -2

Query: 514  SGYTPLHLAAREGHEDVAAFL--LDHGASLSITTKKGFTPLHVAAKYGKLEVASLLLQKS 571
            + +  LH A +   +DV   L  LD G  +        T LH     G +++AS+LL+  
Sbjct: 1464 ASFCALHCAXQL--QDVETLLAYLDIGMHVDTRDSHHETALHAVCYVGSVKMASVLLKHX 1291

Query: 572  ASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIAT 631
            A  +A      TPLH+ A   +  +   L+  GA  +A  K+  TP+  A  KN  DI  
Sbjct: 1290 ADVNARNNVDRTPLHIXAIEGHLGLVEELVRHGADFNAEDKDHLTPVFNACVKNDTDIVR 1111

Query: 632  SLLEYGADANAVTRQGIASV----------------------------HLAAQEGHVDMV 663
             LLE GA AN   R    +V                            H+A + G+++M 
Sbjct: 1110 YLLESGARANTTARPIFHAVKYGYSEIVQLLLVHGAAVNSLPGTKSPLHIACRNGNIEMA 931

Query: 664  SLLLSRNANVNLSNKSGLTPLHLAAQE-DRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCH 722
              ++   ANVN  +K G TPLH++ +      +  +L+  GA+V         PLH+ C 
Sbjct: 930  RTVIIAGANVNAVDKDGNTPLHISVRAPSSAQLVRLLIRFGANVKWGNDNQQIPLHLACL 751

Query: 723  YGNIKIVNFLLQHSAKVNAKTKNGYTALHQAAQQGHTHIINVLLQNNASPNELTVNGNTA 782
            Y N++    LL   +  N  +   +T LH A   G+  I+ ++LQ ++  N      N  
Sbjct: 750  YSNLETARLLLHCGSCSNELSSKLWTPLHYAVIGGNVDIVRLVLQGSSDVNSPDGRNNAP 571

Query: 783  LAIA 786
            L +A
Sbjct: 570  LHLA 559

 Score = 72.0 bits (175), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 53/186 (28%), Positives = 87/186 (46%)
 Frame = -2

Query: 615  YTPLHIAAKKNQMDIATSLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLSRNANVN 674
            +  LH A +   ++   + L+ G   +        ++H     G V M S+LL   A+VN
Sbjct: 1458 FCALHCAXQLQDVETLLAYLDIGMHVDTRDSHHETALHAVCYVGSVKMASVLLKHXADVN 1279

Query: 675  LSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQ 734
              N    TPLH+ A E  + + E LV  GA  +A+ K   TP+   C   +  IV +LL+
Sbjct: 1278 ARNNVDRTPLHIXAIEGHLGLVEELVRHGADFNAEDKDHLTPVFNACVKNDTDIVRYLLE 1099

Query: 735  HSAKVNAKTKNGYTALHQAAQQGHTHIINVLLQNNASPNELTVNGNTALAIARRLGYISV 794
              A+ N   +     +  A + G++ I+ +LL + A+ N L     + L IA R G I +
Sbjct: 1098 SGARANTTAR----PIFHAVKYGYSEIVQLLLVHGAAVNSLP-GTKSPLHIACRNGNIEM 934

Query: 795  VDTLKV 800
              T+ +
Sbjct: 933  ARTVII 916

 Score = 58.9 bits (141), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 41/147 (27%), Positives = 77/147 (52%)
 Frame = -2

Query: 29  LRAARAGHLEKALDYIKNGVDVNICNQNGLNALHLASKEGHVEVVSELLQREANVDAATK 88
           +RA  +  L + L  I+ G +V   N N    LHLA    ++E    LL   +  +  + 
Sbjct: 858 VRAPSSAQLVRLL--IRFGANVKWGNDNQQIPLHLACLYSNLETARLLLHCGSCSNELSS 685

Query: 89  KGNTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVRFLLDNGAS 148
           K  T LH A + G  ++V++++   ++VN+       PL++A  +  + + R LL +GA+
Sbjct: 684 KLWTPLHYAVIGGNVDIVRLVLQGSSDVNSPDGRNNAPLHLACMKQCIGIARCLLRHGAN 505

Query: 149 QSLATEDGFTPLAVALQQGHDQVVSLL 175
            +++  +G TPL +A+   + ++V LL
Sbjct: 504 VNVSGYNGRTPLHIAISHHNLELVLLL 424
>06253
          Length = 1049

 Score =  139 bits (349), Expect = 1e-32,   Method: Compositional matrix adjust.
 Identities = 89/258 (34%), Positives = 132/258 (51%), Gaps = 21/258 (8%)
 Frame = -1

Query: 550  TPLHVAAKYGKLEVASLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHA 609
            TPLH AA +G+ +V   LL+  A+  A    GL PLH A  + + +V  LLL  GA P+A
Sbjct: 1040 TPLHFAAGFGRKDVVEHLLENGANVHARDDGGLIPLHNACSFGHAEVVQLLLRHGADPNA 861

Query: 610  AAKNGYTPLHIAAKKNQMDIATSLLEYGADANAVTRQGIASVHLA--------------- 654
                 YTPLH AA K ++D+   LL+  AD N     G  ++ LA               
Sbjct: 860  RDNWNYTPLHEAAIKGKIDVCIVLLQQCADPNIRNTDGKTALDLADASAKAVLTGEYKKD 681

Query: 655  -----AQEGHVD-MVSLLLSRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDA 708
                 A+ G+ + M++LL   N N + S+    TPLHLAA  +R  + ++L+  GA V A
Sbjct: 680  ELLEAARSGNEEQMMALLTPLNVNCHASDGRKSTPLHLAAGYNRTRIVQLLLQHGADVHA 501

Query: 709  QTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTALHQAAQQGHTHIINVLLQN 768
            + K G  PLH  C YG+ ++   LL   A VNA     +T LH+AA +    + ++LL +
Sbjct: 500  KDKGGLVPLHNACSYGHFEVTEMLLXAGASVNAVDLWQFTPLHEAASKSRVEVCSLLLAH 321

Query: 769  NASPNELTVNGNTALAIA 786
             A PN +  +  + + +A
Sbjct: 320  GADPNLVNCHSKSIIDVA 267

 Score =  134 bits (337), Expect = 3e-31,   Method: Compositional matrix adjust.
 Identities = 87/242 (35%), Positives = 125/242 (51%), Gaps = 21/242 (8%)
 Frame = -1

Query: 484  TPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLAAREGHEDVAAFLLDHGASLSI 543
            TPLH +A  G+ D+V+ LL+ GA+ +A    G  PLH A   GH +V   LL HGA  + 
Sbjct: 1040 TPLHFAAGFGRKDVVEHLLENGANVHARDDGGLIPLHNACSFGHAEVVQLLLRHGADPNA 861

Query: 544  TTKKGFTPLHVAAKYGKLEVASLLLQKSASP--------------DAAGKSGLTP----- 584
                 +TPLH AA  GK++V  +LLQ+ A P              DA+ K+ LT      
Sbjct: 860  RDNWNYTPLHEAAIKGKIDVCIVLLQQCADPNIRNTDGKTALDLADASAKAVLTGEYKKD 681

Query: 585  --LHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATSLLEYGADANA 642
              L  A   + +++  LL     + HA+     TPLH+AA  N+  I   LL++GAD +A
Sbjct: 680  ELLEAARSGNEEQMMALLTPLNVNCHASDGRKSTPLHLAAGYNRTRIVQLLLQHGADVHA 501

Query: 643  VTRQGIASVHLAAQEGHVDMVSLLLSRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQ 702
              + G+  +H A   GH ++  +LL   A+VN  +    TPLH AA + RV V  +L+  
Sbjct: 500  KDKGGLVPLHNACSYGHFEVTEMLLXAGASVNAVDLWQFTPLHEAASKSRVEVCSLLLAH 321

Query: 703  GA 704
            GA
Sbjct: 320  GA 315

 Score =  131 bits (330), Expect = 2e-30,   Method: Compositional matrix adjust.
 Identities = 92/246 (37%), Positives = 120/246 (48%), Gaps = 22/246 (8%)
 Frame = -1

Query: 352  TALHVAAHCGHYKVAKVLLDKKASPNAKALNGFTPLHIACKKNRIRVMELLLKHGASIQA 411
            T LH AA  G   V + LL+  A+ +A+   G  PLH AC      V++LLL+HGA   A
Sbjct: 1040 TPLHFAAGFGRKDVVEHLLENGANVHARDDGGLIPLHNACSFGHAEVVQLLLRHGADPNA 861

Query: 412  VTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMA--------------- 456
                  TP+H AA  G +++   L+   A PN  N  G+TAL +A               
Sbjct: 860  RDNWNYTPLHEAAIKGKIDVCIVLLQQCADPNIRNTDGKTALDLADASAKAVLTGEYKKD 681

Query: 457  -----ARSGQAEVVRYLVQDGAQVEAKAKDDQ--TPLHISARLGKADIVQQLLQQGASPN 509
                 ARSG  E +  L+     V   A D +  TPLH++A   +  IVQ LLQ GA  +
Sbjct: 680  ELLEAARSGNEEQMMALLTP-LNVNCHASDGRKSTPLHLAAGYNRTRIVQLLLQHGADVH 504

Query: 510  AATTSGYTPLHLAAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVASLLLQ 569
            A    G  PLH A   GH +V   LL  GAS++      FTPLH AA   ++EV SLLL 
Sbjct: 503  AKDKGGLVPLHNACSYGHFEVTEMLLXAGASVNAVDLWQFTPLHEAASKSRVEVCSLLLA 324

Query: 570  KSASPD 575
              A P+
Sbjct: 323  HGADPN 306

 Score =  131 bits (329), Expect = 3e-30,   Method: Compositional matrix adjust.
 Identities = 93/251 (37%), Positives = 124/251 (49%), Gaps = 21/251 (8%)
 Frame = -1

Query: 448  RGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGAS 507
            R  T LH AA  G+ +VV +L+++GA V A+      PLH +   G A++VQ LL+ GA 
Sbjct: 1049 RKSTPLHFAAGFGRKDVVEHLLENGANVHARDDGGLIPLHNACSFGHAEVVQLLLRHGAD 870

Query: 508  PNAATTSGYTPLHLAAREGHEDVAAFLLDHGASLSITTKKGFTPLHVA---------AKY 558
            PNA     YTPLH AA +G  DV   LL   A  +I    G T L +A          +Y
Sbjct: 869  PNARDNWNYTPLHEAAIKGKIDVCIVLLQQCADPNIRNTDGKTALDLADASAKAVLTGEY 690

Query: 559  GK---LEVA---------SLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGAS 606
             K   LE A         +LL   + +  A+     TPLH+AA Y+  ++  LLL  GA 
Sbjct: 689  KKDELLEAARSGNEEQMMALLTPLNVNCHASDGRKSTPLHLAAGYNRTRIVQLLLQHGAD 510

Query: 607  PHAAAKNGYTPLHIAAKKNQMDIATSLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLL 666
             HA  K G  PLH A      ++   LL  GA  NAV       +H AA +  V++ SLL
Sbjct: 509  VHAKDKGGLVPLHNACSYGHFEVTEMLLXAGASVNAVDLWQFTPLHEAASKSRVEVCSLL 330

Query: 667  LSRNANVNLSN 677
            L+  A+ NL N
Sbjct: 329  LAHGADPNLVN 297

 Score =  108 bits (270), Expect = 2e-23,   Method: Compositional matrix adjust.
 Identities = 100/341 (29%), Positives = 142/341 (41%), Gaps = 46/341 (13%)
 Frame = -1

Query: 220  TPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRGNANMVKLLLDRGAKIDA 279
            TPLH AA +G  +V   LL   A V       + PLH A   G+A +V+LLL  GA  +A
Sbjct: 1040 TPLHFAAGFGRKDVVEHLLENGANVHARDDGGLIPLHNACSFGHAEVVQLLLRHGADPNA 861

Query: 280  KTRDGLTPLHCGARSGHEQVVEMLLDRSAPILSKTKNGLSPLHMAT-------------- 325
            +     TPLH  A  G   V  +LL + A    +  +G + L +A               
Sbjct: 860  RDNWNYTPLHEAAIKGKIDVCIVLLQQCADPNIRNTDGKTALDLADASAKAVLTGEYKKD 681

Query: 326  -------QGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKASPNA 378
                    G+    + LL   NV          T LH+AA     ++ ++LL   A  +A
Sbjct: 680  ELLEAARSGNEEQMMALLTPLNVNCHASDGRKSTPLHLAAGYNRTRIVQLLLQHGADVHA 501

Query: 379  KALNGFTPLHIACKKNRIRVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHH 438
            K   G  PLH AC      V E+LL  GAS+ AV     TP+H AA    V + S L+ H
Sbjct: 500  KDKGGLVPLHNACSYGHFEVTEMLLXAGASVNAVDLWQFTPLHEAASKSRVEVCSLLLAH 321

Query: 439  GASPNTTNV----------------------RGETALHMAARSGQAEVVRYLVQDGAQVE 476
            GA PN  N                       +G + L  A ++  A V +YL  D    +
Sbjct: 320  GADPNLVNCHSKSIIDVAPTRELQERIQFEYKGHSLLEGARQADLARVKKYLAVDIVNFK 141

Query: 477  AKAKDDQTPLHISARL---GKADIVQQLLQQGASPNAATTS 514
                 D T LH +A      +  +V+ L+++G + N  T +
Sbjct: 140  HPYNGD-TALHCAAASPFPKRKQVVELLVRKGGNLNEKTKT 21

 Score =  104 bits (259), Expect = 4e-22,   Method: Compositional matrix adjust.
 Identities = 81/248 (32%), Positives = 116/248 (46%)
 Frame = -1

Query: 61   LHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQAEVVKVLVTNGANVNAQS 120
            LH A+  G  +VV  LL+  ANV A    G   LH A   G AEVV++L+ +GA+ NA+ 
Sbjct: 1034 LHFAAGFGRKDVVEHLLENGANVHARDDGGLIPLHNACSFGHAEVVQLLLRHGADPNARD 855

Query: 121  QNGFTPLYMAAQENHLEVVRFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLLENDT 180
               +TPL+ AA +  ++V   LL   A  ++   DG T L +A     D     +L  + 
Sbjct: 854  NWNYTPLHEAAIKGKIDVCIVLLQQCADPNIRNTDGKTALDLA-----DASAKAVLTGEY 690

Query: 181  KGKVRLPALHIAARKDDTKAAALLLQNDTNADVESKSGFTPLHIAAHYGNINVATLLLNR 240
            K    L A   A   ++ +  ALL   + N         TPLH+AA Y    +  LLL  
Sbjct: 689  KKDELLEA---ARSGNEEQMMALLTPLNVNCHASDGRKSTPLHLAAGYNRTRIVQLLLQH 519

Query: 241  AAAVDFTARNDITPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVV 300
             A V    +  + PLH A   G+  + ++LL  GA ++A      TPLH  A     +V 
Sbjct: 518  GADVHAKDKGGLVPLHNACSYGHFEVTEMLLXAGASVNAVDLWQFTPLHEAASKSRVEVC 339

Query: 301  EMLLDRSA 308
             +LL   A
Sbjct: 338  SLLLAHGA 315

 Score =  100 bits (248), Expect = 7e-21,   Method: Compositional matrix adjust.
 Identities = 77/237 (32%), Positives = 105/237 (44%), Gaps = 21/237 (8%)
 Frame = -1

Query: 583  TPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATSLLEYGADANA 642
            TPLH AA +  + V   LL+ GA+ HA    G  PLH A      ++   LL +GAD NA
Sbjct: 1040 TPLHFAAGFGRKDVVEHLLENGANVHARDDGGLIPLHNACSFGHAEVVQLLLRHGADPNA 861

Query: 643  VTRQGIASVHLAAQEGHVDMVSLLLSRNANVNLSNKSGLTPLHLAAQEDRVNVA------ 696
                    +H AA +G +D+  +LL + A+ N+ N  G T L LA    +  +       
Sbjct: 860  RDNWNYTPLHEAAIKGKIDVCIVLLQQCADPNIRNTDGKTALDLADASAKAVLTGEYKKD 681

Query: 697  EVLVNQGAHVDAQTKMGYTPLHVGCH---------------YGNIKIVNFLLQHSAKVNA 741
            E+L    +  + Q     TPL+V CH               Y   +IV  LLQH A V+A
Sbjct: 680  ELLEAARSGNEEQMMALLTPLNVNCHASDGRKSTPLHLAAGYNRTRIVQLLLQHGADVHA 501

Query: 742  KTKNGYTALHQAAQQGHTHIINVLLQNNASPNELTVNGNTALAIARRLGYISVVDTL 798
            K K G   LH A   GH  +  +LL   AS N + +   T L  A     + V   L
Sbjct: 500  KDKGGLVPLHNACSYGHFEVTEMLLXAGASVNAVDLWQFTPLHEAASKSRVEVCSLL 330

 Score = 92.0 bits (227), Expect = 2e-18,   Method: Compositional matrix adjust.
 Identities = 102/364 (28%), Positives = 152/364 (41%), Gaps = 8/364 (2%)
 Frame = -1

Query: 125  TPLYMAAQENHLEVVRFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLLENDTKGKV 184
            TPL+ AA     +VV  LL+NGA+     + G  PL  A   GH +VV LLL +      
Sbjct: 1040 TPLHFAAGFGRKDVVEHLLENGANVHARDDGGLIPLHNACSFGHAEVVQLLLRHGADPNA 861

Query: 185  R----LPALHIAARKDDTKAAALLLQNDTNADVESKSGFTPLHIAAHYGNINVATLLLNR 240
            R       LH AA K       +LLQ   + ++ +  G T L +A             + 
Sbjct: 860  RDNWNYTPLHEAAIKGKIDVCIVLLQQCADPNIRNTDGKTALDLA-------------DA 720

Query: 241  AAAVDFTARNDITPLHVASKRGN-ANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQV 299
            +A    T       L  A++ GN   M+ LL        A      TPLH  A     ++
Sbjct: 719  SAKAVLTGEYKKDELLEAARSGNEEQMMALLTPLNVNCHASDGRKSTPLHLAAGYNRTRI 540

Query: 300  VEMLLDRSAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAH 359
            V++LL   A + +K K GL PLH A    H    ++LL     V+ V     T LH AA 
Sbjct: 539  VQLLLQHGADVHAKDKGGLVPLHNACSYGHFEVTEMLLXAGASVNAVDLWQFTPLHEAAS 360

Query: 360  CGHYKVAKVLLDKKASPNAKALNGFTPLHIACKKNRIRVMELLLKHGASIQAVTESGLTP 419
                +V  +LL   A PN    +  + + +A  +     ++   K  + ++   ++ L  
Sbjct: 359  KSRVEVCSLLLAHGADPNLVNCHSKSIIDVAPTRELQERIQFEYKGHSLLEGARQADLA- 183

Query: 420  IHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARS---GQAEVVRYLVQDGAQVE 476
              V  ++  V+IV+   H           G+TALH AA S    + +VV  LV+ G  + 
Sbjct: 182  -RVKKYLA-VDIVN-FKH--------PYNGDTALHCAAASPFPKRKQVVELLVRKGGNLN 36

Query: 477  AKAK 480
             K K
Sbjct: 35   EKTK 24

 Score = 91.3 bits (225), Expect = 3e-18,   Method: Compositional matrix adjust.
 Identities = 74/238 (31%), Positives = 113/238 (47%), Gaps = 6/238 (2%)
 Frame = -1

Query: 44  IKNGVDVNICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQA 103
           ++NG +V+  +  GL  LH A   GH EVV  LL+  A+ +A      T LH A++ G+ 
Sbjct: 986 LENGANVHARDDGGLIPLHNACSFGHAEVVQLLLRHGADPNARDNWNYTPLHEAAIKGKI 807

Query: 104 EVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVRFLLDNGASQSLATEDGFTPLAVA 163
           +V  VL+   A+ N ++ +G T L +A             D  A   L  E     L  A
Sbjct: 806 DVCIVLLQQCADPNIRNTDGKTALDLA-------------DASAKAVLTGEYKKDELLEA 666

Query: 164 LQQGHDQVVSLLLE------NDTKGKVRLPALHIAARKDDTKAAALLLQNDTNADVESKS 217
            + G+++ +  LL       + + G+   P LH+AA  + T+   LLLQ+  +   + K 
Sbjct: 665 ARSGNEEQMMALLTPLNVNCHASDGRKSTP-LHLAAGYNRTRIVQLLLQHGADVHAKDKG 489

Query: 218 GFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRGNANMVKLLLDRGA 275
           G  PLH A  YG+  V  +LL   A+V+       TPLH A+ +    +  LLL  GA
Sbjct: 488 GLVPLHNACSYGHFEVTEMLLXAGASVNAVDLWQFTPLHEAASKSRVEVCSLLLAHGA 315

 Score = 64.3 bits (155), Expect = 4e-10,   Method: Compositional matrix adjust.
 Identities = 47/125 (37%), Positives = 69/125 (55%), Gaps = 2/125 (1%)
 Frame = -1

Query: 29  LRAARAGHLEKALDYIKNGVDVNICNQNGLNA--LHLASKEGHVEVVSELLQREANVDAA 86
           L AAR+G+ E+ +  +   ++VN    +G  +  LHLA+      +V  LLQ  A+V A 
Sbjct: 674 LEAARSGNEEQMMALL-TPLNVNCHASDGRKSTPLHLAAGYNRTRIVQLLLQHGADVHAK 498

Query: 87  TKKGNTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVRFLLDNG 146
            K G   LH A   G  EV ++L+  GA+VNA     FTPL+ AA ++ +EV   LL +G
Sbjct: 497 DKGGLVPLHNACSYGHFEVTEMLLXAGASVNAVDLWQFTPLHEAASKSRVEVCSLLLAHG 318

Query: 147 ASQSL 151
           A  +L
Sbjct: 317 ADPNL 303
>13462
          Length = 1388

 Score =  113 bits (283), Expect = 6e-25,   Method: Compositional matrix adjust.
 Identities = 97/313 (30%), Positives = 152/313 (48%), Gaps = 15/313 (4%)
 Frame = +3

Query: 377 NAKALNGFTPLHIACKKNRIRVMELLLKHGASIQAVTESGLT--PIHVAAFM--GHVNIV 432
           N    NG T L +ACK NR  ++ +LL+ GA +  +    L   P+H A+    G++ IV
Sbjct: 57  NGLCGNGLTLLCVACKLNRADLVPVLLQRGA-LPDLPSLYLNKRPLHYASHHSNGNLGIV 233

Query: 433 SQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARL 492
           S L+ +GA PN  +  G TALH+A      +VVR L++ G  V     D++TPL  +   
Sbjct: 234 SMLLAYGAQPNVQDEDGNTALHLACSESNVDVVRLLLEWGGDVAVADIDNETPLVRACLA 413

Query: 493 GKADIVQQLLQQGASPNAATTSGYTPLHLAAREGHEDVAAFLLDHGASLSITTKKGFTPL 552
              ++V  LL  G+ PN    S   PL +  R    +    L+  GA ++     G T L
Sbjct: 414 NSVELVDLLLHAGSDPN---HSHGRPLEIVVRAPSLESLKLLIGAGAQVT-----GNTYL 569

Query: 553 HVAAKYGKLEVASLLLQKSASPDAAGKSGLTPLH---VAAHYDNQKVALLLLDQGASPHA 609
             A+++  L++  +L       +  G+ GLT LH   ++    +  V LLLL  G++P+ 
Sbjct: 570 SFASEHNYLDMMKVLHNYGVDVNGTGRLGLTALHHACISQEATHDAVRLLLL-WGSNPNL 746

Query: 610 AAKNGYTPLHIAAKKNQMDIATSLLEYGADANAV----TRQGIASVHLAAQ----EGHVD 661
               G TPLH A +   +     LL YGAD N +    T   IA++    Q      ++D
Sbjct: 747 VTGTGDTPLHFACQTFAVSKVRLLLMYGADVNQIDGTHTSPLIAALTTRRQPQNDASYLD 926

Query: 662 MVSLLLSRNANVN 674
           ++ LLL+  A ++
Sbjct: 927 LIRLLLAAGARLS 965

 Score =  105 bits (262), Expect = 2e-22,   Method: Compositional matrix adjust.
 Identities = 89/274 (32%), Positives = 129/274 (47%), Gaps = 5/274 (1%)
 Frame = +3

Query: 449 GETALHMAARSGQAEVVRYLVQDGAQVEAKA-KDDQTPLHISARL--GKADIVQQLLQQG 505
           G T L +A +  +A++V  L+Q GA  +  +   ++ PLH ++    G   IV  LL  G
Sbjct: 75  GLTLLCVACKLNRADLVPVLLQRGALPDLPSLYLNKRPLHYASHHSNGNLGIVSMLLAYG 254

Query: 506 ASPNAATTSGYTPLHLAAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVAS 565
           A PN     G T LHLA  E + DV   LL+ G  +++      TPL  A     +E+  
Sbjct: 255 AQPNVQDEDGNTALHLACSESNVDVVRLLLEWGGDVAVADIDNETPLVRACLANSVELVD 434

Query: 566 LLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKN 625
           LLL   + P+    S   PL +     + +   LL+  GA        G T L  A++ N
Sbjct: 435 LLLHAGSDPN---HSHGRPLEIVVRAPSLESLKLLIGAGAQ-----VTGNTYLSFASEHN 590

Query: 626 QMDIATSLLEYGADANAVTRQGIASVHLA--AQEGHVDMVSLLLSRNANVNLSNKSGLTP 683
            +D+   L  YG D N   R G+ ++H A  +QE   D V LLL   +N NL   +G TP
Sbjct: 591 YLDMMKVLHNYGVDVNGTGRLGLTALHHACISQEATHDAVRLLLLWGSNPNLVTGTGDTP 770

Query: 684 LHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPL 717
           LH A Q   V+   +L+  GA V+       +PL
Sbjct: 771 LHFACQTFAVSKVRLLLMYGADVNQIDGTHTSPL 872

 Score = 93.2 bits (230), Expect = 8e-19,   Method: Compositional matrix adjust.
 Identities = 81/276 (29%), Positives = 130/276 (47%), Gaps = 6/276 (2%)
 Frame = +3

Query: 316 NGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTA--LHVAAH--CGHYKVAKVLLD 371
           NGL+ L +A + +  + V +LLQ    + D+ + YL    LH A+H   G+  +  +LL 
Sbjct: 72  NGLTLLCVACKLNRADLVPVLLQRGA-LPDLPSLYLNKRPLHYASHHSNGNLGIVSMLLA 248

Query: 372 KKASPNAKALNGFTPLHIACKKNRIRVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNI 431
             A PN +  +G T LH+AC ++ + V+ LLL+ G  +        TP+  A     V +
Sbjct: 249 YGAQPNVQDEDGNTALHLACSESNVDVVRLLLEWGGDVAVADIDNETPLVRACLANSVEL 428

Query: 432 VSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISAR 491
           V  L+H G+ PN ++ R    L +  R+   E ++ L+  GAQV        T L  ++ 
Sbjct: 429 VDLLLHAGSDPNHSHGR---PLEIVVRAPSLESLKLLIGAGAQVTGN-----TYLSFASE 584

Query: 492 LGKADIVQQLLQQGASPNAATTSGYTPLHLA--AREGHEDVAAFLLDHGASLSITTKKGF 549
               D+++ L   G   N     G T LH A  ++E   D    LL  G++ ++ T  G 
Sbjct: 585 HNYLDMMKVLHNYGVDVNGTGRLGLTALHHACISQEATHDAVRLLLLWGSNPNLVTGTGD 764

Query: 550 TPLHVAAKYGKLEVASLLLQKSASPDAAGKSGLTPL 585
           TPLH A +   +    LLL   A  +    +  +PL
Sbjct: 765 TPLHFACQTFAVSKVRLLLMYGADVNQIDGTHTSPL 872

 Score = 87.4 bits (215), Expect = 4e-17,   Method: Compositional matrix adjust.
 Identities = 72/257 (28%), Positives = 120/257 (46%), Gaps = 5/257 (1%)
 Frame = +3

Query: 547 KGFTPLHVAAKYGKLEVASLLLQKSASPDAAGKS-GLTPLHVAAHYDNQKVAL--LLLDQ 603
            G T L VA K  + ++  +LLQ+ A PD         PLH A+H+ N  + +  +LL  
Sbjct: 72  NGLTLLCVACKLNRADLVPVLLQRGALPDLPSLYLNKRPLHYASHHSNGNLGIVSMLLAY 251

Query: 604 GASPHAAAKNGYTPLHIAAKKNQMDIATSLLEYGADANAVTRQGIASVHLAAQEGHVDMV 663
           GA P+   ++G T LH+A  ++ +D+   LLE+G D           +  A     V++V
Sbjct: 252 GAQPNVQDEDGNTALHLACSESNVDVVRLLLEWGGDVAVADIDNETPLVRACLANSVELV 431

Query: 664 SLLLSRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHY 723
            LLL   ++ N S+     PL +  +   +   ++L+  GA V   T + +   H     
Sbjct: 432 DLLLHAGSDPNHSHGR---PLEIVVRAPSLESLKLLIGAGAQVTGNTYLSFASEH----- 587

Query: 724 GNIKIVNFLLQHSAKVNAKTKNGYTALHQA--AQQGHTHIINVLLQNNASPNELTVNGNT 781
             + ++  L  +   VN   + G TALH A  +Q+     + +LL   ++PN +T  G+T
Sbjct: 588 NYLDMMKVLHNYGVDVNGTGRLGLTALHHACISQEATHDAVRLLLLWGSNPNLVTGTGDT 767

Query: 782 ALAIARRLGYISVVDTL 798
            L  A +   +S V  L
Sbjct: 768 PLHFACQTFAVSKVRLL 818

 Score = 82.8 bits (203), Expect = 1e-15,   Method: Compositional matrix adjust.
 Identities = 94/306 (30%), Positives = 141/306 (46%), Gaps = 18/306 (5%)
 Frame = +3

Query: 50  VNICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKGNT-ALHIAS--LAGQAEVV 106
           VN    NGL  L +A K    ++V  LLQR A  D  +   N   LH AS    G   +V
Sbjct: 54  VNGLCGNGLTLLCVACKLNRADLVPVLLQRGALPDLPSLYLNKRPLHYASHHSNGNLGIV 233

Query: 107 KVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVRFLLDNGASQSLATEDGFTPLAVALQQ 166
            +L+  GA  N Q ++G T L++A  E++++VVR LL+ G   ++A  D  TPL  A   
Sbjct: 234 SMLLAYGAQPNVQDEDGNTALHLACSESNVDVVRLLLEWGGDVAVADIDNETPLVRACLA 413

Query: 167 GHDQVVSLLLE-----NDTKGKVRLPALHIAARKDDTKAAALLLQNDTNADVESKSGFTP 221
              ++V LLL      N + G+     L I  R    ++  LL+           +G T 
Sbjct: 414 NSVELVDLLLHAGSDPNHSHGR----PLEIVVRAPSLESLKLLIGAGAQV-----TGNTY 566

Query: 222 LHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVA--SKRGNANMVKLLLDRGAKIDA 279
           L  A+ +  +++  +L N    V+ T R  +T LH A  S+    + V+LLL  G+  + 
Sbjct: 567 LSFASEHNYLDMMKVLHNYGVDVNGTGRLGLTALHHACISQEATHDAVRLLLLWGSNPNL 746

Query: 280 KTRDGLTPLHCGARSGHEQVVEMLLDRSAPILSKTKNGLSPLHMAT------QGD--HLN 331
            T  G TPLH   ++     V +LL   A +        SPL  A       Q D  +L+
Sbjct: 747 VTGTGDTPLHFACQTFAVSKVRLLLMYGADVNQIDGTHTSPLIAALTTRRQPQNDASYLD 926

Query: 332 CVQLLL 337
            ++LLL
Sbjct: 927 LIRLLL 944

 Score = 75.5 bits (184), Expect = 2e-13,   Method: Compositional matrix adjust.
 Identities = 96/339 (28%), Positives = 156/339 (46%), Gaps = 15/339 (4%)
 Frame = +3

Query: 250 NDITPLHVASKRGNANMVKLLLDRGAKIDAKTRD-GLTPLHCGAR--SGHEQVVEMLLDR 306
           N +T L VA K   A++V +LL RGA  D  +      PLH  +   +G+  +V MLL  
Sbjct: 72  NGLTLLCVACKLNRADLVPVLLQRGALPDLPSLYLNKRPLHYASHHSNGNLGIVSMLLAY 251

Query: 307 SAPILSKTKNGLSPLHMATQGDHLNCVQLLLQH--NVPVDDVTNDYLTALHVAAHCGHYK 364
            A    + ++G + LH+A    +++ V+LLL+   +V V D+ N+  T L  A      +
Sbjct: 252 GAQPNVQDEDGNTALHLACSESNVDVVRLLLEWGGDVAVADIDNE--TPLVRACLANSVE 425

Query: 365 VAKVLLDKKASPNAKALNGFTPLHIACKKNRIRVMELLLKHGASIQAVTESGLTPIHVAA 424
           +  +LL   + PN    +G  PL I  +   +  ++LL+  GA +     +G T +  A+
Sbjct: 426 LVDLLLHAGSDPNHS--HG-RPLEIVVRAPSLESLKLLIGAGAQV-----TGNTYLSFAS 581

Query: 425 FMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQA--EVVRYLVQDGAQVEAKAKDD 482
              +++++  L ++G   N T   G TALH A  S +A  + VR L+  G+         
Sbjct: 582 EHNYLDMMKVLHNYGVDVNGTGRLGLTALHHACISQEATHDAVRLLLLWGSNPNLVTGTG 761

Query: 483 QTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPL--HLAARE------GHEDVAAFL 534
            TPLH + +      V+ LL  GA  N    +  +PL   L  R        + D+   L
Sbjct: 762 DTPLHFACQTFAVSKVRLLLMYGADVNQIDGTHTSPLIAALTTRRQPQNDASYLDLIRLL 941

Query: 535 LDHGASLSITTKKGFTPLHVAAKYGKLEVASLLLQKSAS 573
           L  GA LS            +A   +++V  + LQ SA+
Sbjct: 942 LAAGARLS------------SAVLERIKVLIVYLQSSAT 1022

 Score = 55.8 bits (133), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 43/141 (30%), Positives = 69/141 (48%), Gaps = 3/141 (2%)
 Frame = +3

Query: 603 QGASPHAAAKNGYTPLHIAAKKNQMDIATSLLEYGADANAVTRQ-GIASVHLAAQE--GH 659
           QG   +    NG T L +A K N+ D+   LL+ GA  +  +       +H A+    G+
Sbjct: 42  QGDLVNGLCGNGLTLLCVACKLNRADLVPVLLQRGALPDLPSLYLNKRPLHYASHHSNGN 221

Query: 660 VDMVSLLLSRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHV 719
           + +VS+LL+  A  N+ ++ G T LHLA  E  V+V  +L+  G  V        TPL  
Sbjct: 222 LGIVSMLLAYGAQPNVQDEDGNTALHLACSESNVDVVRLLLEWGGDVAVADIDNETPLVR 401

Query: 720 GCHYGNIKIVNFLLQHSAKVN 740
            C   ++++V+ LL   +  N
Sbjct: 402 ACLANSVELVDLLLHAGSDPN 464

 Score = 50.8 bits (120), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 44/129 (34%), Positives = 61/129 (47%), Gaps = 10/129 (7%)
 Frame = +3

Query: 47  GVDVNICNQNGLNALHLA--SKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQAE 104
           GVDVN   + GL ALH A  S+E   + V  LL   +N +  T  G+T LH A       
Sbjct: 624 GVDVNGTGRLGLTALHHACISQEATHDAVRLLLLWGSNPNLVTGTGDTPLHFACQTFAVS 803

Query: 105 VVKVLVTNGANVNAQSQNGFTPLYMAA--------QENHLEVVRFLLDNGASQSLATEDG 156
            V++L+  GA+VN       +PL  A           ++L+++R LL  GA  S A  + 
Sbjct: 804 KVRLLLMYGADVNQIDGTHTSPLIAALTTRRQPQNDASYLDLIRLLLAAGARLSSAVLER 983

Query: 157 FTPLAVALQ 165
              L V LQ
Sbjct: 984 IKVLIVYLQ 1010
>14005
          Length = 1745

 Score =  112 bits (281), Expect = 1e-24,   Method: Compositional matrix adjust.
 Identities = 77/243 (31%), Positives = 127/243 (52%), Gaps = 4/243 (1%)
 Frame = -1

Query: 286  TPLHCGARSGHEQVVEMLLDRSAPILSKTKNGLSP-LHMATQGDHLNCVQLLLQHNVPVD 344
            TPL   +R GH  VV  LL      +++    L P L+ A  G+ +  V+ L+++   V+
Sbjct: 1739 TPLIIASRMGHLAVVSELLKVPGIDVNERDEKLRPALYFACMGNDIELVKQLVRYGARVN 1560

Query: 345  DV-TNDYLTALHVAAHCGHYKVAKVLLDKKASPNAKALNGFTPLHIACKKNRIRVMELLL 403
               T  + T  H     G  ++A  LL   A+  ++ ++G TPL +ACK ++  V  LL+
Sbjct: 1559 AYSTETWWTPFHACCKRGDPRIALYLLRHGANKESRTVDGKTPLVVACKNDKAEVALLLI 1380

Query: 404  KHGASIQAVTE-SGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQA 462
            + GA++    + +  TP+H A    ++ ++ +L+ HGA  +  N +G TALH+A+  G  
Sbjct: 1379 RSGANVNVSCDITANTPVHFACQRPNIELLKRLVLHGADVDKPNAKGHTALHVASVRGFK 1200

Query: 463  EVVRYLVQ-DGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHL 521
            + V YL+    A+V A        LHI+ R   AD+V+ LL +GA+P      G+TP + 
Sbjct: 1199 QHVIYLLDFCDAEVNAATLKGNNALHIACRGKHADLVELLLHKGANPAQRNQRGWTPRNS 1020

Query: 522  AAR 524
            A R
Sbjct: 1019 AGR 1011

 Score =  111 bits (277), Expect = 3e-24,   Method: Compositional matrix adjust.
 Identities = 79/238 (33%), Positives = 125/238 (52%), Gaps = 4/238 (1%)
 Frame = -1

Query: 450  ETALHMAARSGQAEVVRYLVQ-DGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASP 508
            ET L +A+R G   VV  L++  G  V  + +  +  L+ +      ++V+QL++ GA  
Sbjct: 1742 ETPLIIASRMGHLAVVSELLKVPGIDVNERDEKLRPALYFACMGNDIELVKQLVRYGARV 1563

Query: 509  NAATT-SGYTPLHLAAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVASLL 567
            NA +T + +TP H   + G   +A +LL HGA+    T  G TPL VA K  K EVA LL
Sbjct: 1562 NAYSTETWWTPFHACCKRGDPRIALYLLRHGANKESRTVDGKTPLVVACKNDKAEVALLL 1383

Query: 568  LQKSASPDAAGK-SGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQ 626
            ++  A+ + +   +  TP+H A    N ++   L+  GA        G+T LH+A+ +  
Sbjct: 1382 IRSGANVNVSCDITANTPVHFACQRPNIELLKRLVLHGADVDKPNAKGHTALHVASVRGF 1203

Query: 627  MDIATSLLEY-GADANAVTRQGIASVHLAAQEGHVDMVSLLLSRNANVNLSNKSGLTP 683
                  LL++  A+ NA T +G  ++H+A +  H D+V LLL + AN    N+ G TP
Sbjct: 1202 KQHVIYLLDFCDAEVNAATLKGNNALHIACRGKHADLVELLLHKGANPAQRNQRGWTP 1029

 Score =  105 bits (261), Expect = 2e-22,   Method: Compositional matrix adjust.
 Identities = 74/246 (30%), Positives = 119/246 (48%), Gaps = 13/246 (5%)
 Frame = -1

Query: 352  TALHVAAHCGHYKVAKVLL----------DKKASPNAKALNGFTPLHIACKKNRIRVMEL 401
            T L +A+  GH  V   LL          D+K  P          L+ AC  N I +++ 
Sbjct: 1739 TPLIIASRMGHLAVVSELLKVPGIDVNERDEKLRP---------ALYFACMGNDIELVKQ 1587

Query: 402  LLKHGASIQAV-TESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSG 460
            L+++GA + A  TE+  TP H     G   I   L+ HGA+  +  V G+T L +A ++ 
Sbjct: 1586 LVRYGARVNAYSTETWWTPFHACCKRGDPRIALYLLRHGANKESRTVDGKTPLVVACKND 1407

Query: 461  QAEVVRYLVQDGAQVEAKAK-DDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPL 519
            +AEV   L++ GA V         TP+H + +    +++++L+  GA  +     G+T L
Sbjct: 1406 KAEVALLLIRSGANVNVSCDITANTPVHFACQRPNIELLKRLVLHGADVDKPNAKGHTAL 1227

Query: 520  HLAAREGHEDVAAFLLDH-GASLSITTKKGFTPLHVAAKYGKLEVASLLLQKSASPDAAG 578
            H+A+  G +    +LLD   A ++  T KG   LH+A +    ++  LLL K A+P    
Sbjct: 1226 HVASVRGFKQHVIYLLDFCDAEVNAATLKGNNALHIACRGKHADLVELLLHKGANPAQRN 1047

Query: 579  KSGLTP 584
            + G TP
Sbjct: 1046 QRGWTP 1029

 Score = 99.0 bits (245), Expect = 2e-20,   Method: Compositional matrix adjust.
 Identities = 69/238 (28%), Positives = 124/238 (52%), Gaps = 4/238 (1%)
 Frame = -1

Query: 483  QTPLHISARLGKADIVQQLLQ-QGASPNAATTSGYTPLHLAAREGHEDVAAFLLDHGASL 541
            +TPL I++R+G   +V +LL+  G   N         L+ A      ++   L+ +GA +
Sbjct: 1742 ETPLIIASRMGHLAVVSELLKVPGIDVNERDEKLRPALYFACMGNDIELVKQLVRYGARV 1563

Query: 542  -SITTKKGFTPLHVAAKYGKLEVASLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLL 600
             + +T+  +TP H   K G   +A  LL+  A+ ++    G TPL VA   D  +VALLL
Sbjct: 1562 NAYSTETWWTPFHACCKRGDPRIALYLLRHGANKESRTVDGKTPLVVACKNDKAEVALLL 1383

Query: 601  LDQGASPHAAAK-NGYTPLHIAAKKNQMDIATSLLEYGADANAVTRQGIASVHLAAQEGH 659
            +  GA+ + +      TP+H A ++  +++   L+ +GAD +    +G  ++H+A+  G 
Sbjct: 1382 IRSGANVNVSCDITANTPVHFACQRPNIELLKRLVLHGADVDKPNAKGHTALHVASVRGF 1203

Query: 660  VDMVSLLLSR-NANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTP 716
               V  LL   +A VN +   G   LH+A +    ++ E+L+++GA+   + + G+TP
Sbjct: 1202 KQHVIYLLDFCDAEVNAATLKGNNALHIACRGKHADLVELLLHKGANPAQRNQRGWTP 1029

 Score = 93.6 bits (231), Expect = 6e-19,   Method: Compositional matrix adjust.
 Identities = 76/254 (29%), Positives = 126/254 (49%), Gaps = 8/254 (3%)
 Frame = -1

Query: 61   LHLASKEGHVEVVSELLQREA-NVDAATKKGNTALHIASLAGQAEVVKVLVTNGANVNAQ 119
            L +AS+ GH+ VVSELL+    +V+   +K   AL+ A +    E+VK LV  GA VNA 
Sbjct: 1733 LIIASRMGHLAVVSELLKVPGIDVNERDEKLRPALYFACMGNDIELVKQLVRYGARVNAY 1554

Query: 120  S-QNGFTPLYMAAQENHLEVVRFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLLEN 178
            S +  +TP +   +     +  +LL +GA++   T DG TPL VA +    +V  LL+ +
Sbjct: 1553 STETWWTPFHACCKRGDPRIALYLLRHGANKESRTVDGKTPLVVACKNDKAEVALLLIRS 1374

Query: 179  DTKGKVRLPA-----LHIAARKDDTKAAALLLQNDTNADVESKSGFTPLHIAAHYGNINV 233
                 V         +H A ++ + +    L+ +  + D  +  G T LH+A+  G    
Sbjct: 1373 GANVNVSCDITANTPVHFACQRPNIELLKRLVLHGADVDKPNAKGHTALHVASVRGFKQH 1194

Query: 234  ATLLLNRA-AAVDFTARNDITPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGA 292
               LL+   A V+         LH+A +  +A++V+LLL +GA    + + G TP +   
Sbjct: 1193 VIYLLDFCDAEVNAATLKGNNALHIACRGKHADLVELLLHKGANPAQRNQRGWTPRNSAG 1014

Query: 293  RSGHEQVVEMLLDR 306
            R    +V+++L  R
Sbjct: 1013 RC--XEVLDILDSR 978

 Score = 93.2 bits (230), Expect = 7e-19,   Method: Compositional matrix adjust.
 Identities = 75/236 (31%), Positives = 116/236 (49%), Gaps = 4/236 (1%)
 Frame = -1

Query: 550  TPLHVAAKYGKLEVASLLLQKSASPDAAGKSGLTP-LHVAAHYDNQKVALLLLDQGASPH 608
            TPL +A++ G L V S LL+            L P L+ A   ++ ++   L+  GA  +
Sbjct: 1739 TPLIIASRMGHLAVVSELLKVPGIDVNERDEKLRPALYFACMGNDIELVKQLVRYGARVN 1560

Query: 609  A-AAKNGYTPLHIAAKKNQMDIATSLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLL 667
            A + +  +TP H   K+    IA  LL +GA+  + T  G   + +A +    ++  LL+
Sbjct: 1559 AYSTETWWTPFHACCKRGDPRIALYLLRHGANKESRTVDGKTPLVVACKNDKAEVALLLI 1380

Query: 668  SRNANVNLS-NKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNI 726
               ANVN+S + +  TP+H A Q   + + + LV  GA VD     G+T LHV    G  
Sbjct: 1379 RSGANVNVSCDITANTPVHFACQRPNIELLKRLVLHGADVDKPNAKGHTALHVASVRGFK 1200

Query: 727  KIVNFLLQHS-AKVNAKTKNGYTALHQAAQQGHTHIINVLLQNNASPNELTVNGNT 781
            + V +LL    A+VNA T  G  ALH A +  H  ++ +LL   A+P +    G T
Sbjct: 1199 QHVIYLLDFCDAEVNAATLKGNNALHIACRGKHADLVELLLHKGANPAQRNQRGWT 1032

 Score = 87.4 bits (215), Expect = 4e-17,   Method: Compositional matrix adjust.
 Identities = 60/184 (32%), Positives = 91/184 (49%), Gaps = 3/184 (1%)
 Frame = -1

Query: 618  LHIAAKKNQMDIATSLLEYGADANAV-TRQGIASVHLAAQEGHVDMVSLLLSRNANVNLS 676
            L+ A   N +++   L+ YGA  NA  T       H   + G   +   LL   AN    
Sbjct: 1631 LYFACMGNDIELVKQLVRYGARVNAYSTETWWTPFHACCKRGDPRIALYLLRHGANKESR 1452

Query: 677  NKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKM-GYTPLHVGCHYGNIKIVNFLLQH 735
               G TPL +A + D+  VA +L+  GA+V+    +   TP+H  C   NI+++  L+ H
Sbjct: 1451 TVDGKTPLVVACKNDKAEVALLLIRSGANVNVSCDITANTPVHFACQRPNIELLKRLVLH 1272

Query: 736  SAKVNAKTKNGYTALHQAAQQGHT-HIINVLLQNNASPNELTVNGNTALAIARRLGYISV 794
             A V+     G+TALH A+ +G   H+I +L   +A  N  T+ GN AL IA R  +  +
Sbjct: 1271 GADVDKPNAKGHTALHVASVRGFKQHVIYLLDFCDAEVNAATLKGNNALHIACRGKHADL 1092

Query: 795  VDTL 798
            V+ L
Sbjct: 1091 VELL 1080

 Score = 87.0 bits (214), Expect = 6e-17,   Method: Compositional matrix adjust.
 Identities = 77/265 (29%), Positives = 118/265 (44%), Gaps = 3/265 (1%)
 Frame = -1

Query: 158  TPLAVALQQGHDQVVSLLLENDTKGKVRLPALHIAARKDDTKAAALLLQNDTNADVESKS 217
            TPL +A + GH  VVS LL        ++P + +  R +  + A                
Sbjct: 1739 TPLIIASRMGHLAVVSELL--------KVPGIDVNERDEKLRPA---------------- 1632

Query: 218  GFTPLHIAAHYGNINVATLLLNRAAAVD-FTARNDITPLHVASKRGNANMVKLLLDRGAK 276
                L+ A    +I +   L+   A V+ ++     TP H   KRG+  +   LL  GA 
Sbjct: 1631 ----LYFACMGNDIELVKQLVRYGARVNAYSTETWWTPFHACCKRGDPRIALYLLRHGAN 1464

Query: 277  IDAKTRDGLTPLHCGARSGHEQVVEMLLDRSAPI-LSKTKNGLSPLHMATQGDHLNCVQL 335
             +++T DG TPL    ++   +V  +L+   A + +S      +P+H A Q  ++  ++ 
Sbjct: 1463 KESRTVDGKTPLVVACKNDKAEVALLLIRSGANVNVSCDITANTPVHFACQRPNIELLKR 1284

Query: 336  LLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLD-KKASPNAKALNGFTPLHIACKKN 394
            L+ H   VD       TALHVA+  G  +    LLD   A  NA  L G   LHIAC+  
Sbjct: 1283 LVLHGADVDKPNAKGHTALHVASVRGFKQHVIYLLDFCDAEVNAATLKGNNALHIACRGK 1104

Query: 395  RIRVMELLLKHGASIQAVTESGLTP 419
               ++ELLL  GA+     + G TP
Sbjct: 1103 HADLVELLLHKGANPAQRNQRGWTP 1029

 Score = 85.5 bits (210), Expect = 2e-16,   Method: Compositional matrix adjust.
 Identities = 68/243 (27%), Positives = 119/243 (48%), Gaps = 4/243 (1%)
 Frame = -1

Query: 517  TPLHLAAREGHEDVAAFLLD-HGASLSITTKKGFTPLHVAAKYGKLEVASLLLQKSASPD 575
            TPL +A+R GH  V + LL   G  ++   +K    L+ A     +E+   L++  A  +
Sbjct: 1739 TPLIIASRMGHLAVVSELLKVPGIDVNERDEKLRPALYFACMGNDIELVKQLVRYGARVN 1560

Query: 576  A-AGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATSLL 634
            A + ++  TP H      + ++AL LL  GA+  +   +G TPL +A K ++ ++A  L+
Sbjct: 1559 AYSTETWWTPFHACCKRGDPRIALYLLRHGANKESRTVDGKTPLVVACKNDKAEVALLLI 1380

Query: 635  EYGADAN-AVTRQGIASVHLAAQEGHVDMVSLLLSRNANVNLSNKSGLTPLHLAAQED-R 692
              GA+ N +        VH A Q  +++++  L+   A+V+  N  G T LH+A+    +
Sbjct: 1379 RSGANVNVSCDITANTPVHFACQRPNIELLKRLVLHGADVDKPNAKGHTALHVASVRGFK 1200

Query: 693  VNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTALHQ 752
             +V  +L    A V+A T  G   LH+ C   +  +V  LL   A    + + G+T  + 
Sbjct: 1199 QHVIYLLDFCDAEVNAATLKGNNALHIACRGKHADLVELLLHKGANPAQRNQRGWTPRNS 1020

Query: 753  AAQ 755
            A +
Sbjct: 1019 AGR 1011

 Score = 66.6 bits (161), Expect = 7e-11,   Method: Compositional matrix adjust.
 Identities = 59/201 (29%), Positives = 86/201 (42%), Gaps = 10/201 (4%)
 Frame = -1

Query: 31   AARAGHLEKALDYIKNGVDVN-ICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKK 89
            A     +E     ++ G  VN    +      H   K G   +   LL+  AN ++ T  
Sbjct: 1622 ACMGNDIELVKQLVRYGARVNAYSTETWWTPFHACCKRGDPRIALYLLRHGANKESRTVD 1443

Query: 90   GNTALHIASLAGQAEVVKVLVTNGANVNAQSQ-NGFTPLYMAAQENHLEVVRFLLDNGAS 148
            G T L +A    +AEV  +L+ +GANVN        TP++ A Q  ++E+++ L+ +GA 
Sbjct: 1442 GKTPLVVACKNDKAEVALLLIRSGANVNVSCDITANTPVHFACQRPNIELLKRLVLHGAD 1263

Query: 149  QSLATEDGFTPLAVALQQGHDQVVSLLLE--------NDTKGKVRLPALHIAARKDDTKA 200
                   G T L VA  +G  Q V  LL+           KG     ALHIA R      
Sbjct: 1262 VDKPNAKGHTALHVASVRGFKQHVIYLLDFCDAEVNAATLKGN---NALHIACRGKHADL 1092

Query: 201  AALLLQNDTNADVESKSGFTP 221
              LLL    N    ++ G+TP
Sbjct: 1091 VELLLHKGANPAQRNQRGWTP 1029

 Score = 54.3 bits (129), Expect = 5e-07,   Method: Compositional matrix adjust.
 Identities = 40/140 (28%), Positives = 72/140 (51%), Gaps = 5/140 (3%)
 Frame = -1

Query: 653  LAAQEGHVDMVSLLLSR-NANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDA-QT 710
            +A++ GH+ +VS LL     +VN  ++     L+ A   + + + + LV  GA V+A  T
Sbjct: 1727 IASRMGHLAVVSELLKVPGIDVNERDEKLRPALYFACMGNDIELVKQLVRYGARVNAYST 1548

Query: 711  KMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTALHQAAQQGHTHIINVLLQNNA 770
            +  +TP H  C  G+ +I  +LL+H A   ++T +G T L  A +     +  +L+++ A
Sbjct: 1547 ETWWTPFHACCKRGDPRIALYLLRHGANKESRTVDGKTPLVVACKNDKAEVALLLIRSGA 1368

Query: 771  SPN---ELTVNGNTALAIAR 787
            + N   ++T N     A  R
Sbjct: 1367 NVNVSCDITANTPVHFACQR 1308
>11295
          Length = 1179

 Score =  111 bits (277), Expect = 3e-24,   Method: Compositional matrix adjust.
 Identities = 92/308 (29%), Positives = 132/308 (42%), Gaps = 38/308 (12%)
 Frame = +1

Query: 297 EQVVEMLLDRSAPILSKTKNGLSPLHMATQGDHLNCVQLLLQ----HNVPVDDVTNDYLT 352
            Q V  LL   A I      GLS LH A  G +    +LLL       + V+  +ND++T
Sbjct: 4   RQTVLTLLQGGAQIYWTDHRGLSALHHACIGRNTEVAELLLDGWNGDGIAVNATSNDHVT 183

Query: 353 ALHVAAHCGHYKVAKVLLDKKASPNAKALNGFTPLHIACKKNRIRVMELLL-KHGASIQA 411
           ALH+A      ++A +LL   A   A  + G TPLH+AC      V  LLL +    + A
Sbjct: 184 ALHIACCLDDREMASLLLKYGAYAMALDVIGHTPLHVACWCGSEGVTRLLLDRSDVDVNA 363

Query: 412 VTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQA--------- 462
           +   G  P+ +A+  G   I+ QL++H A     +    T  H A R  +          
Sbjct: 364 LDHDGKXPLRLASECGFHYIIRQLLYHNADHTIRDAAEFTPFHCAIRYCRVLAVKTFLVW 543

Query: 463 ------------------------EVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIV 498
                                   E++  L++ GA V        TPLH  +R G   ++
Sbjct: 544 FPDLIHSFYNDLSPTFMACLQCDKEMLSLLIKFGASVNCADHYHYTPLHYISRRGHLTML 723

Query: 499 QQLLQQGASPNAATTSGYTPLHLAAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKY 558
           Q LLQ  A PN     G TPL++A+ EGH  +   LL  GA + +   +   P+H A K 
Sbjct: 724 QLLLQGKAEPNVVDDEGITPLYIASCEGHVTIVNILLQSGAKIYMPCAR--DPVHAACKA 897

Query: 559 GKLEVASL 566
           G  EV +L
Sbjct: 898 GH-EVIAL 918

 Score =  109 bits (273), Expect = 9e-24,   Method: Compositional matrix adjust.
 Identities = 90/313 (28%), Positives = 133/313 (42%), Gaps = 7/313 (2%)
 Frame = +1

Query: 197 DTKAAALLLQNDTNADVESKSGFTPLHIAAHYGNINVATLLLN----RAAAVDFTARNDI 252
           D +    LLQ           G + LH A    N  VA LLL+       AV+ T+ + +
Sbjct: 1   DRQTVLTLLQGGAQIYWTDHRGLSALHHACIGRNTEVAELLLDGWNGDGIAVNATSNDHV 180

Query: 253 TPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRS-APIL 311
           T LH+A    +  M  LLL  GA   A    G TPLH     G E V  +LLDRS   + 
Sbjct: 181 TALHIACCLDDREMASLLLKYGAYAMALDVIGHTPLHVACWCGSEGVTRLLLDRSDVDVN 360

Query: 312 SKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDY--LTALHVAAHCGHYKVAKVL 369
           +   +G  PL +A++      ++ LL HN   D    D    T  H A         K  
Sbjct: 361 ALDHDGKXPLRLASECGFHYIIRQLLYHNA--DHTIRDAAEFTPFHCAIRYCRVLAVKTF 534

Query: 370 LDKKASPNAKALNGFTPLHIACKKNRIRVMELLLKHGASIQAVTESGLTPIHVAAFMGHV 429
           L           N  +P  +AC +    ++ LL+K GAS+        TP+H  +  GH+
Sbjct: 535 LVWFPDLIHSFYNDLSPTFMACLQCDKEMLSLLIKFGASVNCADHYHYTPLHYISRRGHL 714

Query: 430 NIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHIS 489
            ++  L+   A PN  +  G T L++A+  G   +V  L+Q GA++      D  P+H +
Sbjct: 715 TMLQLLLQGKAEPNVVDDEGITPLYIASCEGHVTIVNILLQSGAKIYMPCARD--PVHAA 888

Query: 490 ARLGKADIVQQLL 502
            + G   I  +  
Sbjct: 889 CKAGHEVIALRFF 927

 Score =  108 bits (271), Expect = 2e-23,   Method: Compositional matrix adjust.
 Identities = 79/270 (29%), Positives = 129/270 (47%), Gaps = 5/270 (1%)
 Frame = +1

Query: 534 LLDHGASLSITTKKGFTPLHVAAKYGKLEVASLLLQ----KSASPDAAGKSGLTPLHVAA 589
           LL  GA +  T  +G + LH A      EVA LLL        + +A     +T LH+A 
Sbjct: 22  LLQGGAQIYWTDHRGLSALHHACIGRNTEVAELLLDGWNGDGIAVNATSNDHVTALHIAC 201

Query: 590 HYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATSLLEYG-ADANAVTRQGI 648
             D++++A LLL  GA   A    G+TPLH+A       +   LL+    D NA+   G 
Sbjct: 202 CLDDREMASLLLKYGAYAMALDVIGHTPLHVACWCGSEGVTRLLLDRSDVDVNALDHDGK 381

Query: 649 ASVHLAAQEGHVDMVSLLLSRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDA 708
             + LA++ G   ++  LL  NA+  + + +  TP H A +  RV   +  +     +  
Sbjct: 382 XPLRLASECGFHYIIRQLLYHNADHTIRDAAEFTPFHCAIRYCRVLAVKTFLVWFPDLIH 561

Query: 709 QTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTALHQAAQQGHTHIINVLLQN 768
                 +P  + C   + ++++ L++  A VN      YT LH  +++GH  ++ +LLQ 
Sbjct: 562 SFYNDLSPTFMACLQCDKEMLSLLIKFGASVNCADHYHYTPLHYISRRGHLTMLQLLLQG 741

Query: 769 NASPNELTVNGNTALAIARRLGYISVVDTL 798
            A PN +   G T L IA   G++++V+ L
Sbjct: 742 KAEPNVVDDEGITPLYIASCEGHVTIVNIL 831

 Score =  105 bits (262), Expect = 1e-22,   Method: Compositional matrix adjust.
 Identities = 96/329 (29%), Positives = 138/329 (41%), Gaps = 4/329 (1%)
 Frame = +1

Query: 104 EVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVRFLLDNGASQSLATEDGFTPLAVA 163
           + V  L+  GA +      G + L+ A    + EV   LLD      +A           
Sbjct: 7   QTVLTLLQGGAQIYWTDHRGLSALHHACIGRNTEVAELLLDGWNGDGIAVNAT------- 165

Query: 164 LQQGHDQVVSLLLENDTKGKVRLPALHIAARKDDTKAAALLLQNDTNADVESKSGFTPLH 223
                         ND      + ALHIA   DD + A+LLL+    A      G TPLH
Sbjct: 166 -------------SND-----HVTALHIACCLDDREMASLLLKYGAYAMALDVIGHTPLH 291

Query: 224 IAAHYGNINVATLLLNRAAAVDFTA--RNDITPLHVASKRGNANMVKLLLDRGAKIDAKT 281
           +A   G+  V  LLL+R+  VD  A   +   PL +AS+ G   +++ LL   A  D   
Sbjct: 292 VACWCGSEGVTRLLLDRSD-VDVNALDHDGKXPLRLASECGFHYIIRQLLYHNA--DHTI 462

Query: 282 RDG--LTPLHCGARSGHEQVVEMLLDRSAPILSKTKNGLSPLHMATQGDHLNCVQLLLQH 339
           RD    TP HC  R      V+  L     ++    N LSP  MA        + LL++ 
Sbjct: 463 RDAAEFTPFHCAIRYCRVLAVKTFLVWFPDLIHSFYNDLSPTFMACLQCDKEMLSLLIKF 642

Query: 340 NVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKASPNAKALNGFTPLHIACKKNRIRVM 399
              V+   + + T LH  +  GH  + ++LL  KA PN     G TPL+IA  +  + ++
Sbjct: 643 GASVNCADHYHYTPLHYISRRGHLTMLQLLLQGKAEPNVVDDEGITPLYIASCEGHVTIV 822

Query: 400 ELLLKHGASIQAVTESGLTPIHVAAFMGH 428
            +LL+ GA I         P+H A   GH
Sbjct: 823 NILLQSGAKIY--MPCARDPVHAACKAGH 903

 Score =  105 bits (261), Expect = 2e-22,   Method: Compositional matrix adjust.
 Identities = 87/278 (31%), Positives = 128/278 (46%), Gaps = 5/278 (1%)
 Frame = +1

Query: 498 VQQLLQQGASPNAATTSGYTPLHLAAREGHEDVAAFLLD----HGASLSITTKKGFTPLH 553
           V  LLQ GA        G + LH A    + +VA  LLD     G +++ T+    T LH
Sbjct: 13  VLTLLQGGAQIYWTDHRGLSALHHACIGRNTEVAELLLDGWNGDGIAVNATSNDHVTALH 192

Query: 554 VAAKYGKLEVASLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQG-ASPHAAAK 612
           +A      E+ASLLL+  A   A    G TPLHVA    ++ V  LLLD+     +A   
Sbjct: 193 IACCLDDREMASLLLKYGAYAMALDVIGHTPLHVACWCGSEGVTRLLLDRSDVDVNALDH 372

Query: 613 NGYTPLHIAAKKNQMDIATSLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLSRNAN 672
           +G  PL +A++     I   LL + AD            H A +   V  V   L    +
Sbjct: 373 DGKXPLRLASECGFHYIIRQLLYHNADHTIRDAAEFTPFHCAIRYCRVLAVKTFLVWFPD 552

Query: 673 VNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFL 732
           +  S  + L+P  +A  +    +  +L+  GA V+      YTPLH     G++ ++  L
Sbjct: 553 LIHSFYNDLSPTFMACLQCDKEMLSLLIKFGASVNCADHYHYTPLHYISRRGHLTMLQLL 732

Query: 733 LQHSAKVNAKTKNGYTALHQAAQQGHTHIINVLLQNNA 770
           LQ  A+ N     G T L+ A+ +GH  I+N+LLQ+ A
Sbjct: 733 LQGKAEPNVVDDEGITPLYIASCEGHVTIVNILLQSGA 846

 Score =  101 bits (251), Expect = 3e-21,   Method: Compositional matrix adjust.
 Identities = 83/305 (27%), Positives = 137/305 (44%), Gaps = 5/305 (1%)
 Frame = +1

Query: 237 LLNRAAAVDFTARNDITPLHVASKRGNANMVKLLLD----RGAKIDAKTRDGLTPLHCGA 292
           LL   A + +T    ++ LH A    N  + +LLLD     G  ++A + D +T LH   
Sbjct: 22  LLQGGAQIYWTDHRGLSALHHACIGRNTEVAELLLDGWNGDGIAVNATSNDHVTALHIAC 201

Query: 293 RSGHEQVVEMLLDRSAPILSKTKNGLSPLHMATQGDHLNCVQLLL-QHNVPVDDVTNDYL 351
                ++  +LL   A  ++    G +PLH+A         +LLL + +V V+ + +D  
Sbjct: 202 CLDDREMASLLLKYGAYAMALDVIGHTPLHVACWCGSEGVTRLLLDRSDVDVNALDHDGK 381

Query: 352 TALHVAAHCGHYKVAKVLLDKKASPNAKALNGFTPLHIACKKNRIRVMELLLKHGASIQA 411
             L +A+ CG + + + LL   A    +    FTP H A +  R+  ++  L     +  
Sbjct: 382 XPLRLASECGFHYIIRQLLYHNADHTIRDAAEFTPFHCAIRYCRVLAVKTFLVWFPDLIH 561

Query: 412 VTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQD 471
              + L+P  +A       ++S L+  GAS N  +    T LH  +R G   +++ L+Q 
Sbjct: 562 SFYNDLSPTFMACLQCDKEMLSLLIKFGASVNCADHYHYTPLHYISRRGHLTMLQLLLQG 741

Query: 472 GAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLAAREGHEDVA 531
            A+      +  TPL+I++  G   IV  LLQ GA           P+H A + GHE +A
Sbjct: 742 KAEPNVVDDEGITPLYIASCEGHVTIVNILLQSGAKIYMPCAR--DPVHAACKAGHEVIA 915

Query: 532 AFLLD 536
               D
Sbjct: 916 LRFFD 930

 Score = 99.0 bits (245), Expect = 2e-20,   Method: Compositional matrix adjust.
 Identities = 94/343 (27%), Positives = 148/343 (43%), Gaps = 11/343 (3%)
 Frame = +1

Query: 463 EVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQG-----ASPNAATTSGYT 517
           + V  L+Q GAQ+        + LH  A +G+   V +LL  G      + NA +    T
Sbjct: 7   QTVLTLLQGGAQIYWTDHRGLSALH-HACIGRNTEVAELLLDGWNGDGIAVNATSNDHVT 183

Query: 518 PLHLAAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVASLLLQKS-ASPDA 576
            LH+A      ++A+ LL +GA        G TPLHVA   G   V  LLL +S    +A
Sbjct: 184 ALHIACCLDDREMASLLLKYGAYAMALDVIGHTPLHVACWCGSEGVTRLLLDRSDVDVNA 363

Query: 577 AGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATSLLEY 636
               G  PL +A+      +   LL   A         +TP H A +  ++    + L +
Sbjct: 364 LDHDGKXPLRLASECGFHYIIRQLLYHNADHTIRDAAEFTPFHCAIRYCRVLAVKTFLVW 543

Query: 637 GADANAVTRQGIASVHLAAQEGHVDMVSLLLSRNANVNLSNKSGLTPLHLAAQEDRVNVA 696
             D        ++   +A  +   +M+SLL+   A+VN ++    TPLH  ++   + + 
Sbjct: 544 FPDLIHSFYNDLSPTFMACLQCDKEMLSLLIKFGASVNCADHYHYTPLHYISRRGHLTML 723

Query: 697 EVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTALHQAAQQ 756
           ++L+   A  +     G TPL++    G++ IVN LLQ  AK+          +H A + 
Sbjct: 724 QLLLQGKAEPNVVDDEGITPLYIASCEGHVTIVNILLQSGAKIYMPCAR--DPVHAACKA 897

Query: 757 GHTHIINVLL-----QNNASPNELTVNGNTALAIARRLGYISV 794
           GH  I          + NA     T+  + ALAI R   Y+ V
Sbjct: 898 GHEVIALRFFDFLGEKLNAKGVCSTMCRSVALAIRRLYMYMLV 1026

 Score = 96.3 bits (238), Expect = 1e-19,   Method: Compositional matrix adjust.
 Identities = 86/302 (28%), Positives = 133/302 (44%), Gaps = 10/302 (3%)
 Frame = +1

Query: 38  EKALDYIKNGVDVNICNQNGLNALHLASKEGHVEVVSELLQREAN-----VDAATKKGNT 92
           +  L  ++ G  +   +  GL+ALH A    + EV +ELL    N     V+A +    T
Sbjct: 7   QTVLTLLQGGAQIYWTDHRGLSALHHACIGRNTEV-AELLLDGWNGDGIAVNATSNDHVT 183

Query: 93  ALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVRFLLDNGASQSLA 152
           ALHIA      E+  +L+  GA   A    G TPL++A       V R LLD       A
Sbjct: 184 ALHIACCLDDREMASLLLKYGAYAMALDVIGHTPLHVACWCGSEGVTRLLLDRSDVDVNA 363

Query: 153 TE-DGFTPLAVALQQGHDQVVSLLLENDTKGKVRLPA----LHIAARKDDTKAAALLLQN 207
            + DG  PL +A + G   ++  LL ++    +R  A     H A R     A    L  
Sbjct: 364 LDHDGKXPLRLASECGFHYIIRQLLYHNADHTIRDAAEFTPFHCAIRYCRVLAVKTFLVW 543

Query: 208 DTNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRGNANMV 267
             +      +  +P  +A    +  + +LL+   A+V+       TPLH  S+RG+  M+
Sbjct: 544 FPDLIHSFYNDLSPTFMACLQCDKEMLSLLIKFGASVNCADHYHYTPLHYISRRGHLTML 723

Query: 268 KLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRSAPILSKTKNGLSPLHMATQG 327
           +LLL   A+ +    +G+TPL+  +  GH  +V +LL   A I         P+H A + 
Sbjct: 724 QLLLQGKAEPNVVDDEGITPLYIASCEGHVTIVNILLQSGAKIYMPCAR--DPVHAACKA 897

Query: 328 DH 329
            H
Sbjct: 898 GH 903

 Score = 67.8 bits (164), Expect = 4e-11,   Method: Compositional matrix adjust.
 Identities = 59/237 (24%), Positives = 97/237 (40%), Gaps = 1/237 (0%)
 Frame = +1

Query: 45  KNGVDVNICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQAE 104
           ++ VDVN  + +G   L LAS+ G   ++ +LL   A+         T  H A    +  
Sbjct: 340 RSDVDVNALDHDGKXPLRLASECGFHYIIRQLLYHNADHTIRDAAEFTPFHCAIRYCRVL 519

Query: 105 VVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVRFLLDNGASQSLATEDGFTPLAVAL 164
            VK  +    ++     N  +P +MA  +   E++  L+  GAS + A    +TPL    
Sbjct: 520 AVKTFLVWFPDLIHSFYNDLSPTFMACLQCDKEMLSLLIKFGASVNCADHYHYTPLHYIS 699

Query: 165 QQGHDQVVSLLLENDTKGKVRLPALHIAARKDDTKAAALLLQNDTNADVESKSGFTPLHI 224
           ++GH  ++                              LLLQ     +V    G TPL+I
Sbjct: 700 RRGHLTMLQ-----------------------------LLLQGKAEPNVVDDEGITPLYI 792

Query: 225 AAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRGNANMVKLLLD-RGAKIDAK 280
           A+  G++ +  +LL   A +      D  P+H A K G+  +     D  G K++AK
Sbjct: 793 ASCEGHVTIVNILLQSGAKIYMPCARD--PVHAACKAGHEVIALRFFDFLGEKLNAK 957

 Score = 35.8 bits (81), Expect = 0.17,   Method: Compositional matrix adjust.
 Identities = 27/90 (30%), Positives = 46/90 (51%), Gaps = 2/90 (2%)
 Frame = +1

Query: 32  ARAGHLEKALDYIKNGVDVNICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKGN 91
           +R GHL      ++   + N+ +  G+  L++AS EGHV +V+ LLQ  A +     +  
Sbjct: 697 SRRGHLTMLQLLLQGKAEPNVVDDEGITPLYIASCEGHVTIVNILLQSGAKIYMPCAR-- 870

Query: 92  TALHIASLAGQAEVVKVLVTN--GANVNAQ 119
             +H A  AG  EV+ +   +  G  +NA+
Sbjct: 871 DPVHAACKAGH-EVIALRFFDFLGEKLNAK 957
>02114
          Length = 1072

 Score = 99.0 bits (245), Expect(2) = 6e-24,   Method: Compositional matrix adjust.
 Identities = 72/261 (27%), Positives = 120/261 (45%), Gaps = 7/261 (2%)
 Frame = +1

Query: 545 TKKGFTPLHVAAKYGKLEVASLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQG 604
           T +G+TP H+AA  G+      L     S  A    G TPLH+A  + +      LL  G
Sbjct: 193 TPRGWTPAHIAAIRGQEGCIQALSNNGVSMSAKDTRGSTPLHLACAHGHSFCVQTLLRCG 372

Query: 605 ASPHAAAKNGYTPLHIAAKKNQMDIATSLLEYGADANAVTRQGIASVHLAAQEGHVDMVS 664
              ++  K  +T +H+++   ++     L+++GA  + +   G    HLAA EGH+  + 
Sbjct: 373 VDVNSVDKTSWTSVHVSSYHGRLGCLQMLIKWGARYDDIDTNGNTPAHLAAMEGHLPCLK 552

Query: 665 LLLSRNA----NVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVD--AQTKMGYTPLH 718
            L+S        +   N  G TP  LA Q  + N+ E + +    +D   Q +    P H
Sbjct: 553 FLVSSEGCPEHTLGARNDHGETPRDLAQQFYKENILEYIDHVQHEMDHPEQAENLAFPAH 732

Query: 719 VGCHYGNIKIVNFLLQHS-AKVNAKTKNGYTALHQAAQQGHTHIINVLLQNNASPNELTV 777
           +  + G +  +  L+++    +N +   G T  H+AA QGH +I+  L++  A       
Sbjct: 733 MAAYNGELDHLRILVENGVVNINERDDKGNTLAHRAAGQGHLNILQWLVEMGADVEISNG 912

Query: 778 NGNTALAIARRLGYISVVDTL 798
            G TA  IARR  +++ V  L
Sbjct: 913 AGETARDIARRFAHLACVKLL 975

 Score = 32.0 bits (71), Expect(2) = 6e-24,   Method: Composition-based stats.
 Identities = 19/67 (28%), Positives = 32/67 (47%), Gaps = 1/67 (1%)
 Frame = +3

Query: 486 LHISARLGKADIVQQLLQQGASPNAATT-SGYTPLHLAAREGHEDVAAFLLDHGASLSIT 544
           +H + R      ++ +++ GAS N       +TP+H A   G  +   +LL HGA  ++T
Sbjct: 12  IHDAVRHSDVLYLEVMVKNGASINEVEDRDNFTPVHTACNIGALECLHWLLWHGADATVT 191

Query: 545 TKKGFTP 551
              G  P
Sbjct: 192 HTXGLDP 212

 Score = 99.0 bits (245), Expect = 1e-20,   Method: Compositional matrix adjust.
 Identities = 74/268 (27%), Positives = 126/268 (47%), Gaps = 7/268 (2%)
 Frame = +1

Query: 253 TPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRSAPILS 312
           TP H+A+ RG    ++ L + G  + AK   G TPLH     GH   V+ LL     + S
Sbjct: 208 TPAHIAAIRGQEGCIQALSNNGVSMSAKDTRGSTPLHLACAHGHSFCVQTLLRCGVDVNS 387

Query: 313 KTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDK 372
             K   + +H+++    L C+Q+L++     DD+  +  T  H+AA  GH    K L+  
Sbjct: 388 VDKTSWTSVHVSSYHGRLGCLQMLIKWGARYDDIDTNGNTPAHLAAMEGHLPCLKFLVSS 567

Query: 373 KASP----NAKALNGFTPLHIACKKNRIRVMELL--LKHGASIQAVTESGLTPIHVAAFM 426
           +  P     A+  +G TP  +A +  +  ++E +  ++H        E+   P H+AA+ 
Sbjct: 568 EGCPEHTLGARNDHGETPRDLAQQFYKENILEYIDHVQHEMDHPEQAENLAFPAHMAAYN 747

Query: 427 GHVNIVSQLMHHG-ASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTP 485
           G ++ +  L+ +G  + N  + +G T  H AA  G   ++++LV+ GA VE      +T 
Sbjct: 748 GELDHLRILVENGVVNINERDDKGNTLAHRAAGQGHLNILQWLVEMGADVEISNGAGETA 927

Query: 486 LHISARLGKADIVQQLLQQGASPNAATT 513
             I+ R      V+ L   G  P   T+
Sbjct: 928 RDIARRFAHLACVKLL---GGEPEEETS 1002

 Score = 97.4 bits (241), Expect = 5e-20,   Method: Compositional matrix adjust.
 Identities = 78/280 (27%), Positives = 125/280 (44%), Gaps = 5/280 (1%)
 Frame = +1

Query: 413 TESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDG 472
           T  G TP H+AA  G    +  L ++G S +  + RG T LH+A   G +  V+ L++ G
Sbjct: 193 TPRGWTPAHIAAIRGQEGCIQALSNNGVSMSAKDTRGSTPLHLACAHGHSFCVQTLLRCG 372

Query: 473 AQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLAAREGHEDVAA 532
             V +  K   T +H+S+  G+   +Q L++ GA  +   T+G TP HLAA EGH     
Sbjct: 373 VDVNSVDKTSWTSVHVSSYHGRLGCLQMLIKWGARYDDIDTNGNTPAHLAAMEGHLPCLK 552

Query: 533 FLLDHGA----SLSITTKKGFTPLHVAAKYGKLEVASLLLQKSASPDAAGKSGLTPLHVA 588
           FL+        +L      G TP  +A ++ K  +   +                  HV 
Sbjct: 553 FLVSSEGCPEHTLGARNDHGETPRDLAQQFYKENILEYI-----------------DHVQ 681

Query: 589 AHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATSLLEYG-ADANAVTRQG 647
              D+ +               A+N   P H+AA   ++D    L+E G  + N    +G
Sbjct: 682 HEMDHPE--------------QAENLAFPAHMAAYNGELDHLRILVENGVVNINERDDKG 819

Query: 648 IASVHLAAQEGHVDMVSLLLSRNANVNLSNKSGLTPLHLA 687
               H AA +GH++++  L+   A+V +SN +G T   +A
Sbjct: 820 NTLAHRAAGQGHLNILQWLVEMGADVEISNGAGETARDIA 939

 Score = 87.4 bits (215), Expect = 4e-17,   Method: Compositional matrix adjust.
 Identities = 72/253 (28%), Positives = 118/253 (46%), Gaps = 9/253 (3%)
 Frame = +1

Query: 284 GLTPLHCGARSGHEQVVEMLLDRSAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPV 343
           G TP H  A  G E  ++ L +    + +K   G +PLH+A    H  CVQ LL+  V V
Sbjct: 202 GWTPAHIAAIRGQEGCIQALSNNGVSMSAKDTRGSTPLHLACAHGHSFCVQTLLRCGVDV 381

Query: 344 DDVTNDYLTALHVAAHCGHYKVAKVLLDKKASPNAKALNGFTPLHIACKKNRIRVMELLL 403
           + V     T++HV+++ G     ++L+   A  +    NG TP H+A  +  +  ++ L+
Sbjct: 382 NSVDKTSWTSVHVSSYHGRLGCLQMLIKWGARYDDIDTNGNTPAHLAAMEGHLPCLKFLV 561

Query: 404 KHGA----SIQAVTESGLTPIHVAAFMGHVNI---VSQLMHHGASPNTTNVRGETALHMA 456
                   ++ A  + G TP  +A      NI   +  + H    P         A HMA
Sbjct: 562 SSEGCPEHTLGARNDHGETPRDLAQQFYKENILEYIDHVQHEMDHPEQAENLAFPA-HMA 738

Query: 457 ARSGQAEVVRYLVQDGAQVEAKAKDDQ--TPLHISARLGKADIVQQLLQQGASPNAATTS 514
           A +G+ + +R LV++G  V    +DD+  T  H +A  G  +I+Q L++ GA    +  +
Sbjct: 739 AYNGELDHLRILVENGV-VNINERDDKGNTLAHRAAGQGHLNILQWLVEMGADVEISNGA 915

Query: 515 GYTPLHLAAREGH 527
           G T   +A R  H
Sbjct: 916 GETARDIARRFAH 954

 Score = 77.0 bits (188), Expect = 6e-14,   Method: Compositional matrix adjust.
 Identities = 69/267 (25%), Positives = 112/267 (41%), Gaps = 16/267 (5%)
 Frame = +1

Query: 218 GFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRGNANMVKLLLDRGAKI 277
           G+TP HIAA  G       L N   ++        TPLH+A   G++  V+ LL  G  +
Sbjct: 202 GWTPAHIAAIRGQEGCIQALSNNGVSMSAKDTRGSTPLHLACAHGHSFCVQTLLRCGVDV 381

Query: 278 DAKTRDGLTPLHCGARSGHEQVVEMLLDRSAPILSKTKNGLSPLHMATQGDHLNCVQLLL 337
           ++  +   T +H  +  G    ++ML+   A       NG +P H+A    HL C++ L 
Sbjct: 382 NSVDKTSWTSVHVSSYHGRLGCLQMLIKWGARYDDIDTNGNTPAHLAAMEGHLPCLKFL- 558

Query: 338 QHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKASPN---------------AKALN 382
                   V+++      + A   H +  + L  +    N                +A N
Sbjct: 559 --------VSSEGCPEHTLGARNDHGETPRDLAQQFYKENILEYIDHVQHEMDHPEQAEN 714

Query: 383 GFTPLHIACKKNRIRVMELLLKHG-ASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGAS 441
              P H+A     +  + +L+++G  +I    + G T  H AA  GH+NI+  L+  GA 
Sbjct: 715 LAFPAHMAAYNGELDHLRILVENGVVNINERDDKGNTLAHRAAGQGHLNILQWLVEMGAD 894

Query: 442 PNTTNVRGETALHMAARSGQAEVVRYL 468
              +N  GETA  +A R      V+ L
Sbjct: 895 VEISNGAGETARDIARRFAHLACVKLL 975

 Score = 73.2 bits (178), Expect = 9e-13,   Method: Compositional matrix adjust.
 Identities = 64/262 (24%), Positives = 119/262 (45%), Gaps = 12/262 (4%)
 Frame = +1

Query: 87  TKKGNTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVRFLLDNG 146
           T +G T  HIA++ GQ   ++ L  NG +++A+   G TPL++A    H   V+ LL  G
Sbjct: 193 TPRGWTPAHIAAIRGQEGCIQALSNNGVSMSAKDTRGSTPLHLACAHGHSFCVQTLLRCG 372

Query: 147 ASQSLATEDGFTPLAVALQQGHDQVVSLLLE-----NDTKGKVRLPALHIAARKDDTKAA 201
              +   +  +T + V+   G    + +L++     +D       PA H+AA +      
Sbjct: 373 VDVNSVDKTSWTSVHVSSYHGRLGCLQMLIKWGARYDDIDTNGNTPA-HLAAMEGHLPCL 549

Query: 202 ALLLQNDTNAD----VESKSGFTPLHIAAHYGNINVATLLLNRAAAVDF--TARNDITPL 255
             L+ ++   +      +  G TP  +A  +   N+   + +    +D    A N   P 
Sbjct: 550 KFLVSSEGCPEHTLGARNDHGETPRDLAQQFYKENILEYIDHVQHEMDHPEQAENLAFPA 729

Query: 256 HVASKRGNANMVKLLLDRG-AKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRSAPILSKT 314
           H+A+  G  + +++L++ G   I+ +   G T  H  A  GH  +++ L++  A +    
Sbjct: 730 HMAAYNGELDHLRILVENGVVNINERDDKGNTLAHRAAGQGHLNILQWLVEMGADVEISN 909

Query: 315 KNGLSPLHMATQGDHLNCVQLL 336
             G +   +A +  HL CV+LL
Sbjct: 910 GAGETARDIARRFAHLACVKLL 975

 Score = 72.0 bits (175), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 64/260 (24%), Positives = 115/260 (44%), Gaps = 2/260 (0%)
 Frame = +1

Query: 46  NGVDVNICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQAEV 105
           NGV ++  +  G   LHLA   GH   V  LL+   +V++  K   T++H++S  G+   
Sbjct: 268 NGVSMSAKDTRGSTPLHLACAHGHSFCVQTLLRCGVDVNSVDKTSWTSVHVSSYHGRLGC 447

Query: 106 VKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVRFLLDNGASQSLATEDGFTPLAVALQ 165
           +++L+  GA  +    NG TP ++AA E HL  ++FL+         + +G     +  +
Sbjct: 448 LQMLIKWGARYDDIDTNGNTPAHLAAMEGHLPCLKFLV---------SSEGCPEHTLGAR 600

Query: 166 QGHDQVVSLLLENDTKGKVRLPALHIAARKDDTKAAALLLQNDTNADVESKSGFTPLHIA 225
             H +    L +   K  +     H+    D  + A  L                P H+A
Sbjct: 601 NDHGETPRDLAQQFYKENILEYIDHVQHEMDHPEQAENLA--------------FPAHMA 738

Query: 226 AHYGNINVATLLLNRAAAVDFTARNDI--TPLHVASKRGNANMVKLLLDRGAKIDAKTRD 283
           A+ G ++   +L+     V+   R+D   T  H A+ +G+ N+++ L++ GA ++     
Sbjct: 739 AYNGELDHLRILVEN-GVVNINERDDKGNTLAHRAAGQGHLNILQWLVEMGADVEISNGA 915

Query: 284 GLTPLHCGARSGHEQVVEML 303
           G T      R  H   V++L
Sbjct: 916 GETARDIARRFAHLACVKLL 975

 Score = 52.0 bits (123), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 59/248 (23%), Positives = 101/248 (40%), Gaps = 8/248 (3%)
 Frame = +1

Query: 31  AARAGHLEKALDYIKNGVDVNICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKG 90
           A   GH       ++ GVDVN  ++    ++H++S  G +  +  L++  A  D     G
Sbjct: 322 ACAHGHSFCVQTLLRCGVDVNSVDKTSWTSVHVSSYHGRLGCLQMLIKWGARYDDIDTNG 501

Query: 91  NTALHIASLAGQAEVVKVLVTNGA----NVNAQSQNGFTPLYMAAQ---ENHLEVVRFLL 143
           NT  H+A++ G    +K LV++       + A++ +G TP  +A Q   EN LE +    
Sbjct: 502 NTPAHLAAMEGHLPCLKFLVSSEGCPEHTLGARNDHGETPRDLAQQFYKENILEYI---- 669

Query: 144 DNGASQSLATEDGFTPLAVALQQGHDQVVSLLLENDTKGKVRLPALHIAARKDDTKAAAL 203
                                    D V   +   +    +  PA H+AA   +     +
Sbjct: 670 -------------------------DHVQHEMDHPEQAENLAFPA-HMAAYNGELDHLRI 771

Query: 204 LLQND-TNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRG 262
           L++N   N +     G T  H AA  G++N+   L+   A V+ +     T   +A +  
Sbjct: 772 LVENGVVNINERDDKGNTLAHRAAGQGHLNILQWLVEMGADVEISNGAGETARDIARRFA 951

Query: 263 NANMVKLL 270
           +   VKLL
Sbjct: 952 HLACVKLL 975

 Score = 32.7 bits (73), Expect = 1.2,   Method: Composition-based stats.
 Identities = 29/99 (29%), Positives = 38/99 (38%), Gaps = 12/99 (12%)
 Frame = +3

Query: 367 KVLLDKKASPN-AKALNGFTPLHIACKKNRIRVMELLLKHGASIQAVTESGLTP------ 419
           +V++   AS N  +  + FTP+H AC    +  +  LL HGA        GL P      
Sbjct: 51  EVMVKNGASINEVEDRDNFTPVHTACNIGALECLHWLLWHGADATVTHTXGLDPCPHRGN 230

Query: 420 -----IHVAAFMGHVNIVSQLMHHGASPNTTNVRGETAL 453
                +H          V Q  H G  P T  VR  T L
Sbjct: 231 SRPGGLHSGPVQQRGQHVGQ-GHAGLYPPTPGVRTRTFL 344
>05924
          Length = 704

 Score =  101 bits (251), Expect = 3e-21,   Method: Compositional matrix adjust.
 Identities = 57/179 (31%), Positives = 93/179 (51%)
 Frame = +1

Query: 397 RVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMA 456
           + ++ L+K G  + A      T +H A  M   ++V  L+  GA+ N+TN  G TALH+A
Sbjct: 7   KAVQRLVKGGVDVNARFWYDSTLLHEAVSMASEDLVQMLIKAGANANSTNQDGRTALHLA 186

Query: 457 ARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGY 516
            R G   +V+ L+  G  V  +  D +T LH++   G  ++V +L+  GA  N   + G 
Sbjct: 187 CRGGYTNIVQILIAAGTDVNRRTVDGKTCLHVAVWRGHTEVVVKLVNAGADVNIPDSVGC 366

Query: 517 TPLHLAAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVASLLLQKSASPD 575
           +PL+ AAR  +  +   L++ GA ++   K  +TPLH A   G + V   LL + A  +
Sbjct: 367 SPLYWAARSNYTAILTVLVNAGAKVNYRVKSKWTPLHAALHLGHMGVVRYLLLQGAETN 543

 Score = 97.1 bits (240), Expect = 5e-20,   Method: Compositional matrix adjust.
 Identities = 59/179 (32%), Positives = 90/179 (50%)
 Frame = +1

Query: 463 EVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLA 522
           + V+ LV+ G  V A+   D T LH +  +   D+VQ L++ GA+ N+    G T LHLA
Sbjct: 7   KAVQRLVKGGVDVNARFWYDSTLLHEAVSMASEDLVQMLIKAGANANSTNQDGRTALHLA 186

Query: 523 AREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVASLLLQKSASPDAAGKSGL 582
            R G+ ++   L+  G  ++  T  G T LHVA   G  EV   L+   A  +     G 
Sbjct: 187 CRGGYTNIVQILIAAGTDVNRRTVDGKTCLHVAVWRGHTEVVVKLVNAGADVNIPDSVGC 366

Query: 583 TPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATSLLEYGADAN 641
           +PL+ AA  +   +  +L++ GA  +   K+ +TPLH A     M +   LL  GA+ N
Sbjct: 367 SPLYWAARSNYTAILTVLVNAGAKVNYRVKSKWTPLHAALHLGHMGVVRYLLLQGAETN 543

 Score = 96.7 bits (239), Expect = 8e-20,   Method: Compositional matrix adjust.
 Identities = 52/163 (31%), Positives = 90/163 (55%)
 Frame = +1

Query: 583 TPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATSLLEYGADANA 642
           T LH A    ++ +  +L+  GA+ ++  ++G T LH+A +    +I   L+  G D N 
Sbjct: 70  TLLHEAVSMASEDLVQMLIKAGANANSTNQDGRTALHLACRGGYTNIVQILIAAGTDVNR 249

Query: 643 VTRQGIASVHLAAQEGHVDMVSLLLSRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQ 702
            T  G   +H+A   GH ++V  L++  A+VN+ +  G +PL+ AA+ +   +  VLVN 
Sbjct: 250 RTVDGKTCLHVAVWRGHTEVVVKLVNAGADVNIPDSVGCSPLYWAARSNYTAILTVLVNA 429

Query: 703 GAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKN 745
           GA V+ + K  +TPLH   H G++ +V +LL   A+ N   ++
Sbjct: 430 GAKVNYRVKSKWTPLHAALHLGHMGVVRYLLLQGAETNITVQD 558

 Score = 94.0 bits (232), Expect = 4e-19,   Method: Compositional matrix adjust.
 Identities = 53/158 (33%), Positives = 84/158 (53%)
 Frame = +1

Query: 352 TALHVAAHCGHYKVAKVLLDKKASPNAKALNGFTPLHIACKKNRIRVMELLLKHGASIQA 411
           T LH A       + ++L+   A+ N+   +G T LH+AC+     ++++L+  G  +  
Sbjct: 70  TLLHEAVSMASEDLVQMLIKAGANANSTNQDGRTALHLACRGGYTNIVQILIAAGTDVNR 249

Query: 412 VTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQD 471
            T  G T +HVA + GH  +V +L++ GA  N  +  G + L+ AARS    ++  LV  
Sbjct: 250 RTVDGKTCLHVAVWRGHTEVVVKLVNAGADVNIPDSVGCSPLYWAARSNYTAILTVLVNA 429

Query: 472 GAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPN 509
           GA+V  + K   TPLH +  LG   +V+ LL QGA  N
Sbjct: 430 GAKVNYRVKSKWTPLHAALHLGHMGVVRYLLLQGAETN 543

 Score = 92.0 bits (227), Expect = 2e-18,   Method: Compositional matrix adjust.
 Identities = 62/184 (33%), Positives = 89/184 (48%)
 Frame = +1

Query: 363 YKVAKVLLDKKASPNAKALNGFTPLHIACKKNRIRVMELLLKHGASIQAVTESGLTPIHV 422
           +K  + L+      NA+     T LH A       ++++L+K GA+  +  + G T +H+
Sbjct: 4   HKAVQRLVKGGVDVNARFWYDSTLLHEAVSMASEDLVQMLIKAGANANSTNQDGRTALHL 183

Query: 423 AAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDD 482
           A   G+ NIV  L+  G   N   V G+T LH+A   G  EVV  LV  GA V       
Sbjct: 184 ACRGGYTNIVQILIAAGTDVNRRTVDGKTCLHVAVWRGHTEVVVKLVNAGADVNIPDSVG 363

Query: 483 QTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLAAREGHEDVAAFLLDHGASLS 542
            +PL+ +AR     I+  L+  GA  N    S +TPLH A   GH  V  +LL  GA  +
Sbjct: 364 CSPLYWAARSNYTAILTVLVNAGAKVNYRVKSKWTPLHAALHLGHMGVVRYLLLQGAETN 543

Query: 543 ITTK 546
           IT +
Sbjct: 544 ITVQ 555

 Score = 92.0 bits (227), Expect = 2e-18,   Method: Compositional matrix adjust.
 Identities = 53/133 (39%), Positives = 73/133 (54%)
 Frame = +1

Query: 44  IKNGVDVNICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQA 103
           IK G + N  NQ+G  ALHLA + G+  +V  L+    +V+  T  G T LH+A   G  
Sbjct: 124 IKAGANANSTNQDGRTALHLACRGGYTNIVQILIAAGTDVNRRTVDGKTCLHVAVWRGHT 303

Query: 104 EVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVRFLLDNGASQSLATEDGFTPLAVA 163
           EVV  LV  GA+VN     G +PLY AA+ N+  ++  L++ GA  +   +  +TPL  A
Sbjct: 304 EVVVKLVNAGADVNIPDSVGCSPLYWAARSNYTAILTVLVNAGAKVNYRVKSKWTPLHAA 483

Query: 164 LQQGHDQVVSLLL 176
           L  GH  VV  LL
Sbjct: 484 LHLGHMGVVRYLL 522

 Score = 90.9 bits (224), Expect = 5e-18,   Method: Compositional matrix adjust.
 Identities = 57/179 (31%), Positives = 91/179 (50%)
 Frame = +1

Query: 267 VKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRSAPILSKTKNGLSPLHMATQ 326
           V+ L+  G  ++A+     T LH       E +V+ML+   A   S  ++G + LH+A +
Sbjct: 13  VQRLVKGGVDVNARFWYDSTLLHEAVSMASEDLVQMLIKAGANANSTNQDGRTALHLACR 192

Query: 327 GDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKASPNAKALNGFTP 386
           G + N VQ+L+     V+  T D  T LHVA   GH +V   L++  A  N     G +P
Sbjct: 193 GGYTNIVQILIAAGTDVNRRTVDGKTCLHVAVWRGHTEVVVKLVNAGADVNIPDSVGCSP 372

Query: 387 LHIACKKNRIRVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTT 445
           L+ A + N   ++ +L+  GA +    +S  TP+H A  +GH+ +V  L+  GA  N T
Sbjct: 373 LYWAARSNYTAILTVLVNAGAKVNYRVKSKWTPLHAALHLGHMGVVRYLLLQGAETNIT 549

 Score = 84.7 bits (208), Expect = 3e-16,   Method: Compositional matrix adjust.
 Identities = 54/170 (31%), Positives = 86/170 (50%)
 Frame = +1

Query: 616 TPLHIAAKKNQMDIATSLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLSRNANVNL 675
           T LH A      D+   L++ GA+AN+  + G  ++HLA + G+ ++V +L++   +VN 
Sbjct: 70  TLLHEAVSMASEDLVQMLIKAGANANSTNQDGRTALHLACRGGYTNIVQILIAAGTDVNR 249

Query: 676 SNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQH 735
               G T LH+A       V   LVN GA V+    +G +PL+         I+  L+  
Sbjct: 250 RTVDGKTCLHVAVWRGHTEVVVKLVNAGADVNIPDSVGCSPLYWAARSNYTAILTVLVNA 429

Query: 736 SAKVNAKTKNGYTALHQAAQQGHTHIINVLLQNNASPNELTVNGNTALAI 785
            AKVN + K+ +T LH A   GH  ++  LL   A  N +TV   T +++
Sbjct: 430 GAKVNYRVKSKWTPLHAALHLGHMGVVRYLLLQGAETN-ITVQDKTVVSL 576

 Score = 80.1 bits (196), Expect = 8e-15,   Method: Compositional matrix adjust.
 Identities = 58/207 (28%), Positives = 94/207 (45%)
 Frame = +1

Query: 44  IKNGVDVNICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQA 103
           +K GVDVN         LH A      ++V  L++  AN ++  + G TALH+A   G  
Sbjct: 25  VKGGVDVNARFWYDSTLLHEAVSMASEDLVQMLIKAGANANSTNQDGRTALHLACRGGYT 204

Query: 104 EVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVRFLLDNGASQSLATEDGFTPLAVA 163
            +V++L+  G +VN ++ +G T L++A    H EVV  L++ GA  ++    G +P    
Sbjct: 205 NIVQILIAAGTDVNRRTVDGKTCLHVAVWRGHTEVVVKLVNAGADVNIPDSVGCSP---- 372

Query: 164 LQQGHDQVVSLLLENDTKGKVRLPALHIAARKDDTKAAALLLQNDTNADVESKSGFTPLH 223
                                    L+ AAR + T    +L+      +   KS +TPLH
Sbjct: 373 -------------------------LYWAARSNYTAILTVLVNAGAKVNYRVKSKWTPLH 477

Query: 224 IAAHYGNINVATLLLNRAAAVDFTARN 250
            A H G++ V   LL + A  + T ++
Sbjct: 478 AALHLGHMGVVRYLLLQGAETNITVQD 558

 Score = 77.8 bits (190), Expect = 3e-14,   Method: Compositional matrix adjust.
 Identities = 54/179 (30%), Positives = 85/179 (47%)
 Frame = +1

Query: 498 VQQLLQQGASPNAATTSGYTPLHLAAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAK 557
           VQ+L++ G   NA      T LH A     ED+   L+  GA+ + T + G T LH+A +
Sbjct: 13  VQRLVKGGVDVNARFWYDSTLLHEAVSMASEDLVQMLIKAGANANSTNQDGRTALHLACR 192

Query: 558 YGKLEVASLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTP 617
            G   +  +L+      +     G T LHVA    + +V + L++ GA  +     G +P
Sbjct: 193 GGYTNIVQILIAAGTDVNRRTVDGKTCLHVAVWRGHTEVVVKLVNAGADVNIPDSVGCSP 372

Query: 618 LHIAAKKNQMDIATSLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLSRNANVNLS 676
           L+ AA+ N   I T L+  GA  N   +     +H A   GH+ +V  LL + A  N++
Sbjct: 373 LYWAARSNYTAILTVLVNAGAKVNYRVKSKWTPLHAALHLGHMGVVRYLLLQGAETNIT 549

 Score = 74.7 bits (182), Expect = 3e-13,   Method: Compositional matrix adjust.
 Identities = 51/184 (27%), Positives = 92/184 (50%), Gaps = 4/184 (2%)
 Frame = +1

Query: 104 EVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVRFLLDNGASQSLATEDGFTPLAVA 163
           + V+ LV  G +VNA+     T L+ A      ++V+ L+  GA+ +   +DG T L +A
Sbjct: 7   KAVQRLVKGGVDVNARFWYDSTLLHEAVSMASEDLVQMLIKAGANANSTNQDGRTALHLA 186

Query: 164 LQQGHDQVVSLLLENDTKGKVRL----PALHIAARKDDTKAAALLLQNDTNADVESKSGF 219
            + G+  +V +L+   T    R       LH+A  +  T+    L+    + ++    G 
Sbjct: 187 CRGGYTNIVQILIAAGTDVNRRTVDGKTCLHVAVWRGHTEVVVKLVNAGADVNIPDSVGC 366

Query: 220 TPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRGNANMVKLLLDRGAKIDA 279
           +PL+ AA      + T+L+N  A V++  ++  TPLH A   G+  +V+ LL +GA+ + 
Sbjct: 367 SPLYWAARSNYTAILTVLVNAGAKVNYRVKSKWTPLHAALHLGHMGVVRYLLLQGAETNI 546

Query: 280 KTRD 283
             +D
Sbjct: 547 TVQD 558

 Score = 74.7 bits (182), Expect = 3e-13,   Method: Compositional matrix adjust.
 Identities = 54/166 (32%), Positives = 82/166 (49%)
 Frame = +1

Query: 633 LLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLSRNANVNLSNKSGLTPLHLAAQEDR 692
           L++ G D NA        +H A      D+V +L+   AN N +N+ G T LHLA +   
Sbjct: 22  LVKGGVDVNARFWYDSTLLHEAVSMASEDLVQMLIKAGANANSTNQDGRTALHLACRGGY 201

Query: 693 VNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTALHQ 752
            N+ ++L+  G  V+ +T  G T LHV    G+ ++V  L+   A VN     G + L+ 
Sbjct: 202 TNIVQILIAAGTDVNRRTVDGKTCLHVAVWRGHTEVVVKLVNAGADVNIPDSVGCSPLYW 381

Query: 753 AAQQGHTHIINVLLQNNASPNELTVNGNTALAIARRLGYISVVDTL 798
           AA+  +T I+ VL+   A  N    +  T L  A  LG++ VV  L
Sbjct: 382 AARSNYTAILTVLVNAGAKVNYRVKSKWTPLHAALHLGHMGVVRYL 519

 Score = 74.7 bits (182), Expect = 3e-13,   Method: Compositional matrix adjust.
 Identities = 51/181 (28%), Positives = 86/181 (47%)
 Frame = +1

Query: 197 DTKAAALLLQNDTNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLH 256
           D KA   L++   + +       T LH A    + ++  +L+   A  + T ++  T LH
Sbjct: 1   DHKAVQRLVKGGVDVNARFWYDSTLLHEAVSMASEDLVQMLIKAGANANSTNQDGRTALH 180

Query: 257 VASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRSAPILSKTKN 316
           +A + G  N+V++L+  G  ++ +T DG T LH     GH +VV  L++  A +      
Sbjct: 181 LACRGGYTNIVQILIAAGTDVNRRTVDGKTCLHVAVWRGHTEVVVKLVNAGADVNIPDSV 360

Query: 317 GLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKASP 376
           G SPL+ A + ++   + +L+     V+       T LH A H GH  V + LL + A  
Sbjct: 361 GCSPLYWAARSNYTAILTVLVNAGAKVNYRVKSKWTPLHAALHLGHMGVVRYLLLQGAET 540

Query: 377 N 377
           N
Sbjct: 541 N 543

 Score = 73.6 bits (179), Expect = 7e-13,   Method: Compositional matrix adjust.
 Identities = 49/149 (32%), Positives = 75/149 (50%)
 Frame = +1

Query: 31  AARAGHLEKALDYIKNGVDVNICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKG 90
           A R G+       I  G DVN    +G   LH+A   GH EVV +L+   A+V+     G
Sbjct: 184 ACRGGYTNIVQILIAAGTDVNRRTVDGKTCLHVAVWRGHTEVVVKLVNAGADVNIPDSVG 363

Query: 91  NTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVRFLLDNGASQS 150
            + L+ A+ +    ++ VLV  GA VN + ++ +TPL+ A    H+ VVR+LL  GA  +
Sbjct: 364 CSPLYWAARSNYTAILTVLVNAGAKVNYRVKSKWTPLHAALHLGHMGVVRYLLLQGAETN 543

Query: 151 LATEDGFTPLAVALQQGHDQVVSLLLEND 179
           +  +D               VVSLL++N+
Sbjct: 544 ITVQD-------------KTVVSLLMDNE 591

 Score = 70.9 bits (172), Expect = 4e-12,   Method: Compositional matrix adjust.
 Identities = 47/163 (28%), Positives = 81/163 (49%), Gaps = 4/163 (2%)
 Frame = +1

Query: 189 LHIAARKDDTKAAALLLQNDTNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFTA 248
           LH A          +L++   NA+  ++ G T LH+A   G  N+  +L+     V+   
Sbjct: 76  LHEAVSMASEDLVQMLIKAGANANSTNQDGRTALHLACRGGYTNIVQILIAAGTDVNRRT 255

Query: 249 RNDITPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRSA 308
            +  T LHVA  RG+  +V  L++ GA ++     G +PL+  ARS +  ++ +L++  A
Sbjct: 256 VDGKTCLHVAVWRGHTEVVVKLVNAGADVNIPDSVGCSPLYWAARSNYTAILTVLVNAGA 435

Query: 309 PILSKTKNGLSPLHMATQGDHLNCVQLLL----QHNVPVDDVT 347
            +  + K+  +PLH A    H+  V+ LL    + N+ V D T
Sbjct: 436 KVNYRVKSKWTPLHAALHLGHMGVVRYLLLQGAETNITVQDKT 564

 Score = 68.2 bits (165), Expect = 3e-11,   Method: Compositional matrix adjust.
 Identities = 46/161 (28%), Positives = 76/161 (47%)
 Frame = +1

Query: 321 LHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKASPNAKA 380
           LH A      + VQ+L++     +    D  TALH+A   G+  + ++L+      N + 
Sbjct: 76  LHEAVSMASEDLVQMLIKAGANANSTNQDGRTALHLACRGGYTNIVQILIAAGTDVNRRT 255

Query: 381 LNGFTPLHIACKKNRIRVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGA 440
           ++G T LH+A  +    V+  L+  GA +      G +P++ AA   +  I++ L++ GA
Sbjct: 256 VDGKTCLHVAVWRGHTEVVVKLVNAGADVNIPDSVGCSPLYWAARSNYTAILTVLVNAGA 435

Query: 441 SPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKD 481
             N       T LH A   G   VVRYL+  GA+     +D
Sbjct: 436 KVNYRVKSKWTPLHAALHLGHMGVVRYLLLQGAETNITVQD 558

 Score = 37.7 bits (86), Expect = 0.039,   Method: Compositional matrix adjust.
 Identities = 23/72 (31%), Positives = 37/72 (51%)
 Frame = +1

Query: 727 KIVNFLLQHSAKVNAKTKNGYTALHQAAQQGHTHIINVLLQNNASPNELTVNGNTALAIA 786
           K V  L++    VNA+     T LH+A       ++ +L++  A+ N    +G TAL +A
Sbjct: 7   KAVQRLVKGGVDVNARFWYDSTLLHEAVSMASEDLVQMLIKAGANANSTNQDGRTALHLA 186

Query: 787 RRLGYISVVDTL 798
            R GY ++V  L
Sbjct: 187 CRGGYTNIVQIL 222
>00540
          Length = 3034

 Score = 83.2 bits (204), Expect = 1e-15,   Method: Compositional matrix adjust.
 Identities = 46/131 (35%), Positives = 75/131 (57%)
 Frame = -2

Query: 372  KKASPNAKALNGFTPLHIACKKNRIRVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNI 431
            K A  N    +  TPL  AC    + V++ L++H A I+     G T + +A + GH+++
Sbjct: 3003 KGAEVNQTTRSNSTPLRAACYDGHLEVVQFLVEHKAEIEIANSHGHTCLMIACYRGHLDV 2824

Query: 432  VSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISAR 491
            V  L++ GA  N  +V+G TALH +A SG+  +++ L+  GA++ AK    QTPL  +A 
Sbjct: 2823 VEYLLYLGAQVNRRSVKGNTALHDSAESGKLSIMKLLLSKGAKM-AKDAYGQTPLSAAAM 2647

Query: 492  LGKADIVQQLL 502
             G  +IV+ L+
Sbjct: 2646 TGHEEIVRYLI 2614

 Score = 77.4 bits (189), Expect = 5e-14,   Method: Compositional matrix adjust.
 Identities = 46/125 (36%), Positives = 76/125 (60%), Gaps = 1/125 (0%)
 Frame = -2

Query: 20   KKSDANASYLRAA-RAGHLEKALDYIKNGVDVNICNQNGLNALHLASKEGHVEVVSELLQ 78
            + + +N++ LRAA   GHLE     +++  ++ I N +G   L +A   GH++VV  LL 
Sbjct: 2985 QTTRSNSTPLRAACYDGHLEVVQFLVEHKAEIEIANSHGHTCLMIACYRGHLDVVEYLLY 2806

Query: 79   REANVDAATKKGNTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEV 138
              A V+  + KGNTALH ++ +G+  ++K+L++ GA + A+   G TPL  AA   H E+
Sbjct: 2805 LGAQVNRRSVKGNTALHDSAESGKLSIMKLLLSKGAKM-AKDAYGQTPLSAAAMTGHEEI 2629

Query: 139  VRFLL 143
            VR+L+
Sbjct: 2628 VRYLI 2614

 Score = 76.3 bits (186), Expect = 9e-14,   Method: Compositional matrix adjust.
 Identities = 45/130 (34%), Positives = 72/130 (55%)
 Frame = -2

Query: 47   GVDVNICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQAEVV 106
            G +VN   ++    L  A  +GH+EVV  L++ +A ++ A   G+T L IA   G  +VV
Sbjct: 3000 GAEVNQTTRSNSTPLRAACYDGHLEVVQFLVEHKAEIEIANSHGHTCLMIACYRGHLDVV 2821

Query: 107  KVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVRFLLDNGASQSLATEDGFTPLAVALQQ 166
            + L+  GA VN +S  G T L+ +A+   L +++ LL  GA  +     G TPL+ A   
Sbjct: 2820 EYLLYLGAQVNRRSVKGNTALHDSAESGKLSIMKLLLSKGAKMA-KDAYGQTPLSAAAMT 2644

Query: 167  GHDQVVSLLL 176
            GH+++V  L+
Sbjct: 2643 GHEEIVRYLI 2614

 Score = 71.2 bits (173), Expect = 3e-12,   Method: Compositional matrix adjust.
 Identities = 47/132 (35%), Positives = 72/132 (54%), Gaps = 2/132 (1%)
 Frame = -2

Query: 472  GAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLAAREGHEDVA 531
            GA+V    + + TPL  +   G  ++VQ L++  A    A + G+T L +A   GH DV 
Sbjct: 3000 GAEVNQTTRSNSTPLRAACYDGHLEVVQFLVEHKAEIEIANSHGHTCLMIACYRGHLDVV 2821

Query: 532  AFLLDHGASLSITTKKGFTPLHVAAKYGKLEVASLLLQKSA--SPDAAGKSGLTPLHVAA 589
             +LL  GA ++  + KG T LH +A+ GKL +  LLL K A  + DA G+   TPL  AA
Sbjct: 2820 EYLLYLGAQVNRRSVKGNTALHDSAESGKLSIMKLLLSKGAKMAKDAYGQ---TPLSAAA 2650

Query: 590  HYDNQKVALLLL 601
               ++++   L+
Sbjct: 2649 MTGHEEIVRYLI 2614

 Score = 70.1 bits (170), Expect = 8e-12,   Method: Compositional matrix adjust.
 Identities = 41/131 (31%), Positives = 68/131 (51%)
 Frame = -2

Query: 668  SRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIK 727
            ++ A VN + +S  TPL  A  +  + V + LV   A ++     G+T L + C+ G++ 
Sbjct: 3006 AKGAEVNQTTRSNSTPLRAACYDGHLEVVQFLVEHKAEIEIANSHGHTCLMIACYRGHLD 2827

Query: 728  IVNFLLQHSAKVNAKTKNGYTALHQAAQQGHTHIINVLLQNNASPNELTVNGNTALAIAR 787
            +V +LL   A+VN ++  G TALH +A+ G   I+ +LL   A   +    G T L+ A 
Sbjct: 2826 VVEYLLYLGAQVNRRSVKGNTALHDSAESGKLSIMKLLLSKGAKMAK-DAYGQTPLSAAA 2650

Query: 788  RLGYISVVDTL 798
              G+  +V  L
Sbjct: 2649 MTGHEEIVRYL 2617

 Score = 65.9 bits (159), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 45/130 (34%), Positives = 60/130 (46%)
 Frame = -2

Query: 439  GASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIV 498
            GA  N T     T L  A   G  EVV++LV+  A++E       T L I+   G  D+V
Sbjct: 3000 GAEVNQTTRSNSTPLRAACYDGHLEVVQFLVEHKAEIEIANSHGHTCLMIACYRGHLDVV 2821

Query: 499  QQLLQQGASPNAATTSGYTPLHLAAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKY 558
            + LL  GA  N  +  G T LH +A  G   +   LL  GA ++     G TPL  AA  
Sbjct: 2820 EYLLYLGAQVNRRSVKGNTALHDSAESGKLSIMKLLLSKGAKMA-KDAYGQTPLSAAAMT 2644

Query: 559  GKLEVASLLL 568
            G  E+   L+
Sbjct: 2643 GHEEIVRYLI 2614

 Score = 65.9 bits (159), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 52/151 (34%), Positives = 68/151 (45%), Gaps = 7/151 (4%)
 Frame = -2

Query: 504  QGASPNAATTSGYTPLHLAAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEV 563
            +GA  N  T S  TPL  A  +GH +V  FL++H A + I    G T L +A   G L+V
Sbjct: 3003 KGAEVNQTTRSNSTPLRAACYDGHLEVVQFLVEHKAEIEIANSHGHTCLMIACYRGHLDV 2824

Query: 564  ASLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGY--TPLHIA 621
               LL   A  +     G T LH +A      +  LLL +GA     AK+ Y  TPL  A
Sbjct: 2823 VEYLLYLGAQVNRRSVKGNTALHDSAESGKLSIMKLLLSKGAK---MAKDAYGQTPLSAA 2653

Query: 622  AKKNQMDIATSLLEY-----GADANAVTRQG 647
            A     +I   L+       G  ANA+   G
Sbjct: 2652 AMTGHEEIVRYLISGPLFTPGEQANALELMG 2560

 Score = 64.7 bits (156), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 43/127 (33%), Positives = 66/127 (51%)
 Frame = -2

Query: 343  VDDVTNDYLTALHVAAHCGHYKVAKVLLDKKASPNAKALNGFTPLHIACKKNRIRVMELL 402
            V+  T    T L  A + GH +V + L++ KA       +G T L IAC +  + V+E L
Sbjct: 2991 VNQTTRSNSTPLRAACYDGHLEVVQFLVEHKAEIEIANSHGHTCLMIACYRGHLDVVEYL 2812

Query: 403  LKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQA 462
            L  GA +   +  G T +H +A  G ++I+  L+  GA     +  G+T L  AA +G  
Sbjct: 2811 LYLGAQVNRRSVKGNTALHDSAESGKLSIMKLLLSKGAK-MAKDAYGQTPLSAAAMTGHE 2635

Query: 463  EVVRYLV 469
            E+VRYL+
Sbjct: 2634 EIVRYLI 2614

 Score = 62.4 bits (150), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 49/167 (29%), Positives = 77/167 (46%)
 Frame = -2

Query: 146  GASQSLATEDGFTPLAVALQQGHDQVVSLLLENDTKGKVRLPALHIAARKDDTKAAALLL 205
            GA  +  T    TPL  A   GH +VV  L+E+  +                        
Sbjct: 3000 GAEVNQTTRSNSTPLRAACYDGHLEVVQFLVEHKAE------------------------ 2893

Query: 206  QNDTNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRGNAN 265
                  ++ +  G T L IA + G+++V   LL   A V+  +    T LH +++ G  +
Sbjct: 2892 -----IEIANSHGHTCLMIACYRGHLDVVEYLLYLGAQVNRRSVKGNTALHDSAESGKLS 2728

Query: 266  MVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRSAPILS 312
            ++KLLL +GAK+ AK   G TPL   A +GHE++V  L+  S P+ +
Sbjct: 2727 IMKLLLSKGAKM-AKDAYGQTPLSAAAMTGHEEIVRYLI--SGPLFT 2596

 Score = 57.0 bits (136), Expect = 7e-08,   Method: Compositional matrix adjust.
 Identities = 43/151 (28%), Positives = 71/151 (47%), Gaps = 5/151 (3%)
 Frame = -2

Query: 570  KSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDI 629
            K A  +   +S  TPL  A +  + +V   L++  A    A  +G+T L IA  +  +D+
Sbjct: 3003 KGAEVNQTTRSNSTPLRAACYDGHLEVVQFLVEHKAEIEIANSHGHTCLMIACYRGHLDV 2824

Query: 630  ATSLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLSRNANVNLSNKSGLTPLHLAAQ 689
               LL  GA  N  + +G  ++H +A+ G + ++ LLLS+ A +   +  G TPL  AA 
Sbjct: 2823 VEYLLYLGAQVNRRSVKGNTALHDSAESGKLSIMKLLLSKGAKMA-KDAYGQTPLSAAAM 2647

Query: 690  EDRVNVAEVLVNQ-----GAHVDAQTKMGYT 715
                 +   L++      G   +A   MG T
Sbjct: 2646 TGHEEIVRYLISGPLFTPGEQANALELMGAT 2554

 Score = 55.5 bits (132), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 42/131 (32%), Positives = 63/131 (48%)
 Frame = -2

Query: 273  RGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRSAPILSKTKNGLSPLHMATQGDHLNC 332
            +GA+++  TR   TPL      GH +VV+ L++  A I     +G + L +A    HL+ 
Sbjct: 3003 KGAEVNQTTRSNSTPLRAACYDGHLEVVQFLVEHKAEIEIANSHGHTCLMIACYRGHLDV 2824

Query: 333  VQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKASPNAKALNGFTPLHIACK 392
            V+ LL     V+  +    TALH +A  G   + K+LL K A   AK   G TPL  A  
Sbjct: 2823 VEYLLYLGAQVNRRSVKGNTALHDSAESGKLSIMKLLLSKGAK-MAKDAYGQTPLSAAAM 2647

Query: 393  KNRIRVMELLL 403
                 ++  L+
Sbjct: 2646 TGHEEIVRYLI 2614

 Score = 50.8 bits (120), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 33/101 (32%), Positives = 50/101 (49%)
 Frame = -2

Query: 81   ANVDAATKKGNTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVR 140
            A V+  T+  +T L  A   G  EVV+ LV + A +   + +G T L +A    HL+VV 
Sbjct: 2997 AEVNQTTRSNSTPLRAACYDGHLEVVQFLVEHKAEIEIANSHGHTCLMIACYRGHLDVVE 2818

Query: 141  FLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLLENDTK 181
            +LL  GA  +  +  G T L  + + G   ++ LLL    K
Sbjct: 2817 YLLYLGAQVNRRSVKGNTALHDSAESGKLSIMKLLLSKGAK 2695

 Score = 50.4 bits (119), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 39/132 (29%), Positives = 64/132 (48%), Gaps = 1/132 (0%)
 Frame = -2

Query: 240  RAAAVDFTARNDITPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQV 299
            + A V+ T R++ TPL  A   G+  +V+ L++  A+I+     G T L      GH  V
Sbjct: 3003 KGAEVNQTTRSNSTPLRAACYDGHLEVVQFLVEHKAEIEIANSHGHTCLMIACYRGHLDV 2824

Query: 300  VEMLLDRSAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPV-DDVTNDYLTALHVAA 358
            VE LL   A +  ++  G + LH + +   L+ ++LLL     +  D      T L  AA
Sbjct: 2823 VEYLLYLGAQVNRRSVKGNTALHDSAESGKLSIMKLLLSKGAKMAKDAYGQ--TPLSAAA 2650

Query: 359  HCGHYKVAKVLL 370
              GH ++ + L+
Sbjct: 2649 MTGHEEIVRYLI 2614

 Score = 37.0 bits (84), Expect = 0.072,   Method: Compositional matrix adjust.
 Identities = 31/109 (28%), Positives = 49/109 (44%), Gaps = 5/109 (4%)
 Frame = -2

Query: 22   SDANASYLRAARAGHLEKALDYIKNGVDVNICNQNGLNALHLASKEGHVEVVSELLQREA 81
            S  +   + A   GHL+     +  G  VN  +  G  ALH +++ G + ++  LL + A
Sbjct: 2877 SHGHTCLMIACYRGHLDVVEYLLYLGAQVNRRSVKGNTALHDSAESGKLSIMKLLLSKGA 2698

Query: 82   NVDAATKKGNTALHIASLAGQAEVVKVLV-----TNGANVNAQSQNGFT 125
             + A    G T L  A++ G  E+V+ L+     T G   NA    G T
Sbjct: 2697 KM-AKDAYGQTPLSAAAMTGHEEIVRYLISGPLFTPGEQANALELMGAT 2554

 Score = 35.8 bits (81), Expect = 0.17,   Method: Compositional matrix adjust.
 Identities = 30/104 (28%), Positives = 49/104 (47%), Gaps = 15/104 (14%)
 Frame = -2

Query: 37   LEKALDYIKNGVDVNICNQNGLNALHLASKE-----GHVE--------VVSELLQREANV 83
            +  A  ++K G    I + +G + LHLA  E     G V         V   L++  A+ 
Sbjct: 1893 MRAAYRFVKTG----ITDPDGASPLHLACMENISSFGRVRMSHFPSLSVTRILIKVGADT 1726

Query: 84   DAATKKGNTALHIASLAGQAE--VVKVLVTNGANVNAQSQNGFT 125
            +A   +GN ALH AS+  +    VV+ L+  GA+ +  ++N  T
Sbjct: 1725 NARDSQGNVALHFASMGKKVRMAVVEALLAGGAHADVCNKNHLT 1594

 Score = 31.2 bits (69), Expect = 3.7,   Method: Compositional matrix adjust.
 Identities = 24/80 (30%), Positives = 36/80 (45%), Gaps = 15/80 (18%)
 Frame = -2

Query: 382  NGFTPLHIACKKN-----RIR--------VMELLLKHGASIQAVTESGLTPIHVAAFMGH 428
            +G +PLH+AC +N     R+R        V  +L+K GA   A    G   +H A+    
Sbjct: 1848 DGASPLHLACMENISSFGRVRMSHFPSLSVTRILIKVGADTNARDSQGNVALHFASMGKK 1669

Query: 429  VN--IVSQLMHHGASPNTTN 446
            V   +V  L+  GA  +  N
Sbjct: 1668 VRMAVVEALLAGGAHADVCN 1609
>02055
          Length = 1740

 Score = 80.9 bits (198), Expect = 4e-15,   Method: Compositional matrix adjust.
 Identities = 73/271 (26%), Positives = 117/271 (43%), Gaps = 33/271 (12%)
 Frame = +3

Query: 432 VSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKD-DQTPLHISA 490
           V  L+  GA  +  N+ G+T LH+A      E +  LV++GA V A+AK  + TPLH++ 
Sbjct: 372 VDDLIRCGADVDFCNMFGDTPLHIATVHANHEAMGALVRNGANVNARAKFLNSTPLHVAC 551

Query: 491 RLGKADIVQQLLQQGASPNAATTSGYTPLHLAAREGHEDVAAFLLDHGASLSIT------ 544
           RL     V  L+Q GA  +    +G TPL +A +     V   LL    S+  T      
Sbjct: 552 RLRGQQEVALLIQLGARIDVNDATGTTPLQMACKRADPAVVNILLRSQPSIVRTEDANKL 731

Query: 545 -----------------------TKKGFTPLHVAAKYGKLEVASLLLQKSA-SPDAAGKS 580
                                    +G TP+H+A      ++A   +  +  + D     
Sbjct: 732 FKYAIQKRQLHIVKMLCEAGVAVNYEGTTPVHIAMDNQAWDIAKFFITSNKHNFDGRDSK 911

Query: 581 GLTPLHVA--AHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATSLLEYGA 638
           G TPL +A  +  D   V+  LL+ G S      NG T L  A ++N+ ++  S+L +  
Sbjct: 912 GRTPLCLALLSGADFHMVS-FLLNVGYSIDQVDSNGETWLLRAGRQNEENLVCSILRFNP 1088

Query: 639 DANAVTRQGIASVHLAAQEGHVDMVSLLLSR 669
           +  A  R  +  V     +GH  +V+ L+ +
Sbjct: 1089NVYAPNRYNVPLVLELFDKGHYAIVNHLVRK 1181

 Score = 79.0 bits (193), Expect = 1e-14,   Method: Compositional matrix adjust.
 Identities = 83/280 (29%), Positives = 125/280 (44%), Gaps = 5/280 (1%)
 Frame = +3

Query: 42  DYIKNGVDVNICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKGN-TALHIAS-L 99
           D I+ G DV+ CN  G   LH+A+   + E +  L++  ANV+A  K  N T LH+A  L
Sbjct: 378 DLIRCGADVDFCNMFGDTPLHIATVHANHEAMGALVRNGANVNARAKFLNSTPLHVACRL 557

Query: 100 AGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVRFLLDNGASQSLATEDGFTP 159
            GQ EV  +L+  GA ++     G TPL MA +     VV  LL +  S  + TED    
Sbjct: 558 RGQQEVA-LLIQLGARIDVNDATGTTPLQMACKRADPAVVNILLRSQPS-IVRTEDANKL 731

Query: 160 LAVALQQGHDQVVSLLLENDTKGKVR-LPALHIAARKDDTKAAALLL-QNDTNADVESKS 217
              A+Q+    +V +L E            +HIA        A   +  N  N D     
Sbjct: 732 FKYAIQKRQLHIVKMLCEAGVAVNYEGTTPVHIAMDNQAWDIAKFFITSNKHNFDGRDSK 911

Query: 218 GFTPLHIAAHYG-NINVATLLLNRAAAVDFTARNDITPLHVASKRGNANMVKLLLDRGAK 276
           G TPL +A   G + ++ + LLN   ++D    N  T L  A ++   N+V  +L     
Sbjct: 912 GRTPLCLALLSGADFHMVSFLLNVGYSIDQVDSNGETWLLRAGRQNEENLVCSILRFNPN 1091

Query: 277 IDAKTRDGLTPLHCGARSGHEQVVEMLLDRSAPILSKTKN 316
           + A  R  +  +      GH  +V  L+ +   I+S  +N
Sbjct: 1092VYAPNRYNVPLVLELFDKGHYAIVNHLVRK---IISTVRN 1202

 Score = 75.5 bits (184), Expect = 2e-13,   Method: Compositional matrix adjust.
 Identities = 76/274 (27%), Positives = 120/274 (43%), Gaps = 4/274 (1%)
 Frame = +3

Query: 498 VQQLLQQGASPNAATTSGYTPLHLAAREGHEDVAAFLLDHGASLSITTK-KGFTPLHVAA 556
           V  L++ GA  +     G TPLH+A    + +    L+ +GA+++   K    TPLHVA 
Sbjct: 372 VDDLIRCGADVDFCNMFGDTPLHIATVHANHEAMGALVRNGANVNARAKFLNSTPLHVAC 551

Query: 557 KY-GKLEVASLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGY 615
           +  G+ EVA LL+Q  A  D    +G TPL +A    +  V  +LL    S     ++  
Sbjct: 552 RLRGQQEVA-LLIQLGARIDVNDATGTTPLQMACKRADPAVVNILLRSQPSI-VRTEDAN 725

Query: 616 TPLHIAAKKNQMDIATSLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLSRNA-NVN 674
                A +K Q+ I   L E G    AV  +G   VH+A      D+    ++ N  N +
Sbjct: 726 KLFKYAIQKRQLHIVKMLCEAGV---AVNYEGTTPVHIAMDNQAWDIAKFFITSNKHNFD 896

Query: 675 LSNKSGLTPLHLAAQED-RVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLL 733
             +  G TPL LA       ++   L+N G  +D     G T L          +V  +L
Sbjct: 897 GRDSKGRTPLCLALLSGADFHMVSFLLNVGYSIDQVDSNGETWLLRAGRQNEENLVCSIL 1076

Query: 734 QHSAKVNAKTKNGYTALHQAAQQGHTHIINVLLQ 767
           + +  V A  +     + +   +GH  I+N L++
Sbjct: 1077RFNPNVYAPNRYNVPLVLELFDKGHYAIVNHLVR 1178

 Score = 71.2 bits (173), Expect = 3e-12,   Method: Compositional matrix adjust.
 Identities = 72/241 (29%), Positives = 115/241 (47%), Gaps = 9/241 (3%)
 Frame = +3

Query: 73  VSELLQREANVDAATKKGNTALHIASLAGQAEVVKVLVTNGANVNAQSQN-GFTPLYMAA 131
           V +L++  A+VD     G+T LHIA++    E +  LV NGANVNA+++    TPL++A 
Sbjct: 372 VDDLIRCGADVDFCNMFGDTPLHIATVHANHEAMGALVRNGANVNARAKFLNSTPLHVAC 551

Query: 132 QENHLEVVRFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLLEND-----TKGKVRL 186
           +    + V  L+  GA   +    G TPL +A ++    VV++LL +      T+   +L
Sbjct: 552 RLRGQQEVALLIQLGARIDVNDATGTTPLQMACKRADPAVVNILLRSQPSIVRTEDANKL 731

Query: 187 PALHIAARKDDTKAAALLLQNDTNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDF 246
                A +K       +L +     + E   G TP+HIA      ++A   +  +   +F
Sbjct: 732 --FKYAIQKRQLHIVKMLCEAGVAVNYE---GTTPVHIAMDNQAWDIAKFFIT-SNKHNF 893

Query: 247 TARNDI--TPLHVASKRG-NANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEML 303
             R+    TPL +A   G + +MV  LL+ G  ID    +G T L    R   E +V  +
Sbjct: 894 DGRDSKGRTPLCLALLSGADFHMVSFLLNVGYSIDQVDSNGETWLLRAGRQNEENLVCSI 1073

Query: 304 L 304
           L
Sbjct: 1074L 1076

 Score = 59.7 bits (143), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 62/225 (27%), Positives = 103/225 (45%), Gaps = 7/225 (3%)
 Frame = +3

Query: 352 TALHVAAHCGHYKVAKVLLDKKASPNAKA--LNGFTPLHIACKKNRIRVMELLLKHGASI 409
           T LH+A    +++    L+   A+ NA+A  LN  TPLH+AC+    + + LL++ GA I
Sbjct: 429 TPLHIATVHANHEAMGALVRNGANVNARAKFLNS-TPLHVACRLRGQQEVALLIQLGARI 605

Query: 410 QAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETA---LHMAARSGQAEVVR 466
                +G TP+ +A       +V+ L+    S     VR E A      A +  Q  +V+
Sbjct: 606 DVNDATGTTPLQMACKRADPAVVNILLRSQPSI----VRTEDANKLFKYAIQKRQLHIVK 773

Query: 467 YLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGA-SPNAATTSGYTPLHLAARE 525
            L + G  V  +     TP+HI+      DI +  +     + +   + G TPL LA   
Sbjct: 774 MLCEAGVAVNYEGT---TPVHIAMDNQAWDIAKFFITSNKHNFDGRDSKGRTPLCLALLS 944

Query: 526 GHE-DVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVASLLLQ 569
           G +  + +FLL+ G S+      G T L  A +  +  +   +L+
Sbjct: 945 GADFHMVSFLLNVGYSIDQVDSNGETWLLRAGRQNEENLVCSILR 1079

 Score = 58.2 bits (139), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 36/110 (32%), Positives = 56/110 (50%), Gaps = 1/110 (0%)
 Frame = +3

Query: 663 VSLLLSRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTK-MGYTPLHVGC 721
           V  L+   A+V+  N  G TPLH+A           LV  GA+V+A+ K +  TPLHV C
Sbjct: 372 VDDLIRCGADVDFCNMFGDTPLHIATVHANHEAMGALVRNGANVNARAKFLNSTPLHVAC 551

Query: 722 HYGNIKIVNFLLQHSAKVNAKTKNGYTALHQAAQQGHTHIINVLLQNNAS 771
                + V  L+Q  A+++     G T L  A ++    ++N+LL++  S
Sbjct: 552 RLRGQQEVALLIQLGARIDVNDATGTTPLQMACKRADPAVVNILLRSQPS 701

 Score = 55.5 bits (132), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 38/142 (26%), Positives = 64/142 (45%), Gaps = 1/142 (0%)
 Frame = +3

Query: 633 LLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLSRNANVNLSNKS-GLTPLHLAAQED 691
           L+  GAD +     G   +H+A    + + +  L+   ANVN   K    TPLH+A +  
Sbjct: 381 LIRCGADVDFCNMFGDTPLHIATVHANHEAMGALVRNGANVNARAKFLNSTPLHVACRLR 560

Query: 692 RVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTALH 751
                 +L+  GA +D     G TPL + C   +  +VN LL+    +  +T++      
Sbjct: 561 GQQEVALLIQLGARIDVNDATGTTPLQMACKRADPAVVNILLRSQPSI-VRTEDANKLFK 737

Query: 752 QAAQQGHTHIINVLLQNNASPN 773
            A Q+   HI+ +L +   + N
Sbjct: 738 YAIQKRQLHIVKMLCEAGVAVN 803
>25470
          Length = 400

 Score = 75.5 bits (184), Expect = 2e-13,   Method: Compositional matrix adjust.
 Identities = 43/101 (42%), Positives = 58/101 (57%)
 Frame = -3

Query: 686 LAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKN 745
           LAA   R +V E L+  GA+V A+   G  PLH  C +G+ ++V  LL+H A  NA+   
Sbjct: 380 LAAGFGRKDVVEHLLENGANVHARDDGGLIPLHNACSFGHAEVVQLLLRHGADPNARDNW 201

Query: 746 GYTALHQAAQQGHTHIINVLLQNNASPNELTVNGNTALAIA 786
            YT LH+AA +G   +  VLLQ  A PN    +G TAL +A
Sbjct: 200 NYTPLHEAAIKGKIDVCIVLLQQCADPNIRNTDGKTALDLA 78

 Score = 75.5 bits (184), Expect = 2e-13,   Method: Compositional matrix adjust.
 Identities = 40/101 (39%), Positives = 57/101 (56%)
 Frame = -3

Query: 488 ISARLGKADIVQQLLQQGASPNAATTSGYTPLHLAAREGHEDVAAFLLDHGASLSITTKK 547
           ++A  G+ D+V+ LL+ GA+ +A    G  PLH A   GH +V   LL HGA  +     
Sbjct: 380 LAAGFGRKDVVEHLLENGANVHARDDGGLIPLHNACSFGHAEVVQLLLRHGADPNARDNW 201

Query: 548 GFTPLHVAAKYGKLEVASLLLQKSASPDAAGKSGLTPLHVA 588
            +TPLH AA  GK++V  +LLQ+ A P+     G T L +A
Sbjct: 200 NYTPLHEAAIKGKIDVCIVLLQQCADPNIRNTDGKTALDLA 78

 Score = 74.7 bits (182), Expect = 3e-13,   Method: Compositional matrix adjust.
 Identities = 43/106 (40%), Positives = 58/106 (54%)
 Frame = -3

Query: 455 MAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTS 514
           +AA  G+ +VV +L+++GA V A+      PLH +   G A++VQ LL+ GA PNA    
Sbjct: 380 LAAGFGRKDVVEHLLENGANVHARDDGGLIPLHNACSFGHAEVVQLLLRHGADPNARDNW 201

Query: 515 GYTPLHLAAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGK 560
            YTPLH AA +G  DV   LL   A  +I    G T L +A    K
Sbjct: 200 NYTPLHEAAIKGKIDVCIVLLQQCADPNIRNTDGKTALDLADASAK 63

 Score = 68.9 bits (167), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 40/107 (37%), Positives = 57/107 (53%)
 Frame = -3

Query: 356 VAAHCGHYKVAKVLLDKKASPNAKALNGFTPLHIACKKNRIRVMELLLKHGASIQAVTES 415
           +AA  G   V + LL+  A+ +A+   G  PLH AC      V++LLL+HGA   A    
Sbjct: 380 LAAGFGRKDVVEHLLENGANVHARDDGGLIPLHNACSFGHAEVVQLLLRHGADPNARDNW 201

Query: 416 GLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQA 462
             TP+H AA  G +++   L+   A PN  N  G+TAL +A  S +A
Sbjct: 200 NYTPLHEAAIKGKIDVCIVLLQQCADPNIRNTDGKTALDLADASAKA 60

 Score = 67.4 bits (163), Expect = 5e-11,   Method: Compositional matrix adjust.
 Identities = 41/101 (40%), Positives = 56/101 (55%)
 Frame = -3

Query: 422 VAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKD 481
           +AA  G  ++V  L+ +GA+ +  +  G   LH A   G AEVV+ L++ GA   A+   
Sbjct: 380 LAAGFGRKDVVEHLLENGANVHARDDGGLIPLHNACSFGHAEVVQLLLRHGADPNARDNW 201

Query: 482 DQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLA 522
           + TPLH +A  GK D+   LLQQ A PN   T G T L LA
Sbjct: 200 NYTPLHEAAIKGKIDVCIVLLQQCADPNIRNTDGKTALDLA 78

 Score = 66.6 bits (161), Expect = 8e-11,   Method: Compositional matrix adjust.
 Identities = 39/101 (38%), Positives = 55/101 (54%)
 Frame = -3

Query: 554 VAAKYGKLEVASLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKN 613
           +AA +G+ +V   LL+  A+  A    GL PLH A  + + +V  LLL  GA P+A    
Sbjct: 380 LAAGFGRKDVVEHLLENGANVHARDDGGLIPLHNACSFGHAEVVQLLLRHGADPNARDNW 201

Query: 614 GYTPLHIAAKKNQMDIATSLLEYGADANAVTRQGIASVHLA 654
            YTPLH AA K ++D+   LL+  AD N     G  ++ LA
Sbjct: 200 NYTPLHEAAIKGKIDVCIVLLQQCADPNIRNTDGKTALDLA 78

 Score = 65.9 bits (159), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 40/101 (39%), Positives = 53/101 (52%)
 Frame = -3

Query: 521 LAAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVASLLLQKSASPDAAGKS 580
           LAA  G +DV   LL++GA++      G  PLH A  +G  EV  LLL+  A P+A    
Sbjct: 380 LAAGFGRKDVVEHLLENGANVHARDDGGLIPLHNACSFGHAEVVQLLLRHGADPNARDNW 201

Query: 581 GLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIA 621
             TPLH AA      V ++LL Q A P+    +G T L +A
Sbjct: 200 NYTPLHEAAIKGKIDVCIVLLQQCADPNIRNTDGKTALDLA 78

 Score = 64.7 bits (156), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 37/101 (36%), Positives = 54/101 (53%)
 Frame = -3

Query: 395 RIRVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALH 454
           R  V+E LL++GA++ A  + GL P+H A   GH  +V  L+ HGA PN  +    T LH
Sbjct: 362 RKDVVEHLLENGANVHARDDGGLIPLHNACSFGHAEVVQLLLRHGADPNARDNWNYTPLH 183

Query: 455 MAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKA 495
            AA  G+ +V   L+Q  A    +  D +T L ++    KA
Sbjct: 182 EAAIKGKIDVCIVLLQQCADPNIRNTDGKTALDLADASAKA 60

 Score = 62.0 bits (149), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 38/98 (38%), Positives = 49/98 (50%)
 Frame = -3

Query: 653 LAAQEGHVDMVSLLLSRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKM 712
           LAA  G  D+V  LL   ANV+  +  GL PLH A       V ++L+  GA  +A+   
Sbjct: 380 LAAGFGRKDVVEHLLENGANVHARDDGGLIPLHNACSFGHAEVVQLLLRHGADPNARDNW 201

Query: 713 GYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTAL 750
            YTPLH     G I +   LLQ  A  N +  +G TAL
Sbjct: 200 NYTPLHEAAIKGKIDVCIVLLQQCADPNIRNTDGKTAL 87

 Score = 60.8 bits (146), Expect = 4e-09,   Method: Compositional matrix adjust.
 Identities = 40/106 (37%), Positives = 58/106 (54%)
 Frame = -3

Query: 58  LNALHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQAEVVKVLVTNGANVN 117
           +N   LA+  G  +VV  LL+  ANV A    G   LH A   G AEVV++L+ +GA+ N
Sbjct: 395 INTPSLAAGFGRKDVVEHLLENGANVHARDDGGLIPLHNACSFGHAEVVQLLLRHGADPN 216

Query: 118 AQSQNGFTPLYMAAQENHLEVVRFLLDNGASQSLATEDGFTPLAVA 163
           A+    +TPL+ AA +  ++V   LL   A  ++   DG T L +A
Sbjct: 215 ARDNWNYTPLHEAAIKGKIDVCIVLLQQCADPNIRNTDGKTALDLA 78

 Score = 58.2 bits (139), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 36/101 (35%), Positives = 52/101 (51%)
 Frame = -3

Query: 587 VAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATSLLEYGADANAVTRQ 646
           +AA +  + V   LL+ GA+ HA    G  PLH A      ++   LL +GAD NA    
Sbjct: 380 LAAGFGRKDVVEHLLENGANVHARDDGGLIPLHNACSFGHAEVVQLLLRHGADPNARDNW 201

Query: 647 GIASVHLAAQEGHVDMVSLLLSRNANVNLSNKSGLTPLHLA 687
               +H AA +G +D+  +LL + A+ N+ N  G T L LA
Sbjct: 200 NYTPLHEAAIKGKIDVCIVLLQQCADPNIRNTDGKTALDLA 78

 Score = 56.6 bits (135), Expect = 9e-08,   Method: Compositional matrix adjust.
 Identities = 39/99 (39%), Positives = 50/99 (50%)
 Frame = -3

Query: 292 ARSGHEQVVEMLLDRSAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYL 351
           A  G + VVE LL+  A + ++   GL PLH A    H   VQLLL+H    +   N   
Sbjct: 374 AGFGRKDVVEHLLENGANVHARDDGGLIPLHNACSFGHAEVVQLLLRHGADPNARDNWNY 195

Query: 352 TALHVAAHCGHYKVAKVLLDKKASPNAKALNGFTPLHIA 390
           T LH AA  G   V  VLL + A PN +  +G T L +A
Sbjct: 194 TPLHEAAIKGKIDVCIVLLQQCADPNIRNTDGKTALDLA 78

 Score = 54.3 bits (129), Expect = 5e-07,   Method: Compositional matrix adjust.
 Identities = 34/98 (34%), Positives = 52/98 (53%)
 Frame = -3

Query: 620 IAAKKNQMDIATSLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLSRNANVNLSNKS 679
           +AA   + D+   LLE GA+ +A    G+  +H A   GH ++V LLL   A+ N  +  
Sbjct: 380 LAAGFGRKDVVEHLLENGANVHARDDGGLIPLHNACSFGHAEVVQLLLRHGADPNARDNW 201

Query: 680 GLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPL 717
             TPLH AA + +++V  VL+ Q A  + +   G T L
Sbjct: 200 NYTPLHEAAIKGKIDVCIVLLQQCADPNIRNTDGKTAL 87

 Score = 53.1 bits (126), Expect = 9e-07,   Method: Compositional matrix adjust.
 Identities = 32/90 (35%), Positives = 49/90 (54%)
 Frame = -3

Query: 96  IASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVRFLLDNGASQSLATED 155
           +A+  G+ +VV+ L+ NGANV+A+   G  PL+ A    H EVV+ LL +GA  +     
Sbjct: 380 LAAGFGRKDVVEHLLENGANVHARDDGGLIPLHNACSFGHAEVVQLLLRHGADPNARDNW 201

Query: 156 GFTPLAVALQQGHDQVVSLLLENDTKGKVR 185
            +TPL  A  +G   V  +LL+      +R
Sbjct: 200 NYTPLHEAAIKGKIDVCIVLLQQCADPNIR 111

 Score = 47.8 bits (112), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 32/101 (31%), Positives = 51/101 (50%)
 Frame = -3

Query: 257 VASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRSAPILSKTKN 316
           +A+  G  ++V+ LL+ GA + A+   GL PLH     GH +VV++LL   A   ++   
Sbjct: 380 LAAGFGRKDVVEHLLENGANVHARDDGGLIPLHNACSFGHAEVVQLLLRHGADPNARDNW 201

Query: 317 GLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVA 357
             +PLH A     ++   +LLQ     +    D  TAL +A
Sbjct: 200 NYTPLHEAAIKGKIDVCIVLLQQCADPNIRNTDGKTALDLA 78

 Score = 47.8 bits (112), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 31/87 (35%), Positives = 49/87 (56%)
 Frame = -3

Query: 44  IKNGVDVNICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQA 103
           ++NG +V+  +  GL  LH A   GH EVV  LL+  A+ +A      T LH A++ G+ 
Sbjct: 338 LENGANVHARDDGGLIPLHNACSFGHAEVVQLLLRHGADPNARDNWNYTPLHEAAIKGKI 159

Query: 104 EVVKVLVTNGANVNAQSQNGFTPLYMA 130
           +V  VL+   A+ N ++ +G T L +A
Sbjct: 158 DVCIVLLQQCADPNIRNTDGKTALDLA 78

 Score = 47.0 bits (110), Expect = 7e-05,   Method: Compositional matrix adjust.
 Identities = 28/85 (32%), Positives = 41/85 (48%)
 Frame = -3

Query: 204 LLQNDTNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRGN 263
           LL+N  N       G  PLH A  +G+  V  LLL   A  +     + TPLH A+ +G 
Sbjct: 341 LLENGANVHARDDGGLIPLHNACSFGHAEVVQLLLRHGADPNARDNWNYTPLHEAAIKGK 162

Query: 264 ANMVKLLLDRGAKIDAKTRDGLTPL 288
            ++  +LL + A  + +  DG T L
Sbjct: 161 IDVCIVLLQQCADPNIRNTDGKTAL 87

 Score = 46.2 bits (108), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 34/101 (33%), Positives = 49/101 (48%)
 Frame = -3

Query: 224 IAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRGNANMVKLLLDRGAKIDAKTRD 283
           +AA +G  +V   LL   A V       + PLH A   G+A +V+LLL  GA  +A+   
Sbjct: 380 LAAGFGRKDVVEHLLENGANVHARDDGGLIPLHNACSFGHAEVVQLLLRHGADPNARDNW 201

Query: 284 GLTPLHCGARSGHEQVVEMLLDRSAPILSKTKNGLSPLHMA 324
             TPLH  A  G   V  +LL + A    +  +G + L +A
Sbjct: 200 NYTPLHEAAIKGKIDVCIVLLQQCADPNIRNTDGKTALDLA 78

 Score = 43.5 bits (101), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 31/91 (34%), Positives = 45/91 (49%)
 Frame = -3

Query: 333 VQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKASPNAKALNGFTPLHIACK 392
           V+ LL++   V    +  L  LH A   GH +V ++LL   A PNA+    +TPLH A  
Sbjct: 350 VEHLLENGANVHARDDGGLIPLHNACSFGHAEVVQLLLRHGADPNARDNWNYTPLHEAAI 171

Query: 393 KNRIRVMELLLKHGASIQAVTESGLTPIHVA 423
           K +I V  +LL+  A        G T + +A
Sbjct: 170 KGKIDVCIVLLQQCADPNIRNTDGKTALDLA 78

 Score = 39.3 bits (90), Expect = 0.015,   Method: Compositional matrix adjust.
 Identities = 37/136 (27%), Positives = 51/136 (37%)
 Frame = -3

Query: 129 MAAQENHLEVVRFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLLENDTKGKVRLPA 188
           +AA     +VV  LL+NGA+     + G  PL  A   GH +VV LLL +      R   
Sbjct: 380 LAAGFGRKDVVEHLLENGANVHARDDGGLIPLHNACSFGHAEVVQLLLRHGADPNAR--- 210

Query: 189 LHIAARKDDTKAAALLLQNDTNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFTA 248
                                         +TPLH AA  G I+V  +LL + A  +   
Sbjct: 209 --------------------------DNWNYTPLHEAAIKGKIDVCIVLLQQCADPNIRN 108

Query: 249 RNDITPLHVASKRGNA 264
            +  T L +A     A
Sbjct: 107 TDGKTALDLADASAKA 60

 Score = 31.6 bits (70), Expect = 3.0,   Method: Compositional matrix adjust.
 Identities = 22/73 (30%), Positives = 36/73 (49%)
 Frame = -3

Query: 31  AARAGHLEKALDYIKNGVDVNICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKG 90
           A   GH E     +++G D N  +      LH A+ +G ++V   LLQ+ A+ +     G
Sbjct: 278 ACSFGHAEVVQLLLRHGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQQCADPNIRNTDG 99

Query: 91  NTALHIASLAGQA 103
            TAL +A  + +A
Sbjct: 98  KTALDLADASAKA 60
>08473
          Length = 942

 Score = 74.7 bits (182), Expect = 3e-13,   Method: Compositional matrix adjust.
 Identities = 47/123 (38%), Positives = 65/123 (52%)
 Frame = -1

Query: 49  DVNICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQAEVVKV 108
           DV++ + N + ALH A    H   V  LLQ  AN       G T L  A+  G+  + K+
Sbjct: 942 DVDMRDSNDMTALHHACAGLHYGCVHALLQGGANPTCMEMGGKTPLFYAAHRGEISICKL 763

Query: 109 LVTNGANVNAQSQNGFTPLYMAAQENHLEVVRFLLDNGASQSLATEDGFTPLAVALQQGH 168
           LV  GANVNA  +   TPL +AA+E + E V FLL  GA+ + A  +G   L  A+  GH
Sbjct: 762 LVDKGANVNAADKMLITPLMVAAREGNREAVEFLLKRGANPNTADREGHLALYYAMAAGH 583

Query: 169 DQV 171
            ++
Sbjct: 582 PEL 574

 Score = 70.5 bits (171), Expect = 6e-12,   Method: Compositional matrix adjust.
 Identities = 43/122 (35%), Positives = 64/122 (52%)
 Frame = -1

Query: 343 VDDVTNDYLTALHVAAHCGHYKVAKVLLDKKASPNAKALNGFTPLHIACKKNRIRVMELL 402
           VD   ++ +TALH A    HY     LL   A+P    + G TPL  A  +  I + +LL
Sbjct: 939 VDMRDSNDMTALHHACAGLHYGCVHALLQGGANPTCMEMGGKTPLFYAAHRGEISICKLL 760

Query: 403 LKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQA 462
           +  GA++ A  +  +TP+ VAA  G+   V  L+  GA+PNT +  G  AL+ A  +G  
Sbjct: 759 VDKGANVNAADKMLITPLMVAAREGNREAVEFLLKRGANPNTADREGHLALYYAMAAGHP 580

Query: 463 EV 464
           E+
Sbjct: 579 EL 574

 Score = 68.6 bits (166), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 41/114 (35%), Positives = 61/114 (53%)
 Frame = -1

Query: 417 LTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVE 476
           +T +H A    H   V  L+  GA+P    + G+T L  AA  G+  + + LV  GA V 
Sbjct: 915 MTALHHACAGLHYGCVHALLQGGANPTCMEMGGKTPLFYAAHRGEISICKLLVDKGANVN 736

Query: 477 AKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLAAREGHEDV 530
           A  K   TPL ++AR G  + V+ LL++GA+PN A   G+  L+ A   GH ++
Sbjct: 735 AADKMLITPLMVAAREGNREAVEFLLKRGANPNTADREGHLALYYAMAAGHPEL 574

 Score = 67.8 bits (164), Expect = 4e-11,   Method: Compositional matrix adjust.
 Identities = 41/118 (34%), Positives = 59/118 (50%)
 Frame = -1

Query: 648 IASVHLAAQEGHVDMVSLLLSRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVD 707
           + ++H A    H   V  LL   AN       G TPL  AA    +++ ++LV++GA+V+
Sbjct: 915 MTALHHACAGLHYGCVHALLQGGANPTCMEMGGKTPLFYAAHRGEISICKLLVDKGANVN 736

Query: 708 AQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTALHQAAQQGHTHIINVL 765
           A  KM  TPL V    GN + V FLL+  A  N   + G+ AL+ A   GH  +  V 
Sbjct: 735 AADKMLITPLMVAAREGNREAVEFLLKRGANPNTADREGHLALYYAMAAGHPELREVF 562

 Score = 66.6 bits (161), Expect = 7e-11,   Method: Compositional matrix adjust.
 Identities = 44/132 (33%), Positives = 65/132 (49%)
 Frame = -1

Query: 179 DTKGKVRLPALHIAARKDDTKAAALLLQNDTNADVESKSGFTPLHIAAHYGNINVATLLL 238
           D +    + ALH A           LLQ   N       G TPL  AAH G I++  LL+
Sbjct: 936 DMRDSNDMTALHHACAGLHYGCVHALLQGGANPTCMEMGGKTPLFYAAHRGEISICKLLV 757

Query: 239 NRAAAVDFTARNDITPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQ 298
           ++ A V+   +  ITPL VA++ GN   V+ LL RGA  +   R+G   L+    +GH +
Sbjct: 756 DKGANVNAADKMLITPLMVAAREGNREAVEFLLKRGANPNTADREGHLALYYAMAAGHPE 577

Query: 299 VVEMLLDRSAPI 310
           + E+  +  AP+
Sbjct: 576 LREVFAN--APL 547

 Score = 65.9 bits (159), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 41/117 (35%), Positives = 59/117 (50%)
 Frame = -1

Query: 475 VEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLAAREGHEDVAAFL 534
           V+ +  +D T LH +        V  LLQ GA+P      G TPL  AA  G   +   L
Sbjct: 939 VDMRDSNDMTALHHACAGLHYGCVHALLQGGANPTCMEMGGKTPLFYAAHRGEISICKLL 760

Query: 535 LDHGASLSITTKKGFTPLHVAAKYGKLEVASLLLQKSASPDAAGKSGLTPLHVAAHY 591
           +D GA+++   K   TPL VAA+ G  E    LL++ A+P+ A + G    H+A +Y
Sbjct: 759 VDKGANVNAADKMLITPLMVAAREGNREAVEFLLKRGANPNTADREG----HLALYY 601

 Score = 59.7 bits (143), Expect = 9e-09,   Method: Compositional matrix adjust.
 Identities = 47/134 (35%), Positives = 65/134 (48%), Gaps = 7/134 (5%)
 Frame = -1

Query: 451 TALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNA 510
           TALH A        V  L+Q GA         +TPL  +A  G+  I + L+ +GA+ NA
Sbjct: 912 TALHHACAGLHYGCVHALLQGGANPTCMEMGGKTPLFYAAHRGEISICKLLVDKGANVNA 733

Query: 511 ATTSGYTPLHLAAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVASLL--- 567
           A     TPL +AAREG+ +   FLL  GA+ +   ++G   L+ A   G  E+  +    
Sbjct: 732 ADKMLITPLMVAAREGNREAVEFLLKRGANPNTADREGHLALYYAMAAGHPELREVFANA 553

Query: 568 -LQKS---ASPDAA 577
            LQ S    SPD A
Sbjct: 552 PLQASWDLRSPDKA 511

 Score = 58.9 bits (141), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 39/105 (37%), Positives = 56/105 (53%)
 Frame = -1

Query: 517 TPLHLAAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVASLLLQKSASPDA 576
           T LH A    H      LL  GA+ +     G TPL  AA  G++ +  LL+ K A+ +A
Sbjct: 912 TALHHACAGLHYGCVHALLQGGANPTCMEMGGKTPLFYAAHRGEISICKLLVDKGANVNA 733

Query: 577 AGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIA 621
           A K  +TPL VAA   N++    LL +GA+P+ A + G+  L+ A
Sbjct: 732 ADKMLITPLMVAAREGNREAVEFLLKRGANPNTADREGHLALYYA 598

 Score = 58.2 bits (139), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 39/114 (34%), Positives = 57/114 (50%)
 Frame = -1

Query: 549 FTPLHVAAKYGKLEVASLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPH 608
            T LH A           LLQ  A+P      G TPL  AAH     +  LL+D+GA+ +
Sbjct: 915 MTALHHACAGLHYGCVHALLQGGANPTCMEMGGKTPLFYAAHRGEISICKLLVDKGANVN 736

Query: 609 AAAKNGYTPLHIAAKKNQMDIATSLLEYGADANAVTRQGIASVHLAAQEGHVDM 662
           AA K   TPL +AA++   +    LL+ GA+ N   R+G  +++ A   GH ++
Sbjct: 735 AADKMLITPLMVAAREGNREAVEFLLKRGANPNTADREGHLALYYAMAAGHPEL 574

 Score = 57.4 bits (137), Expect = 5e-08,   Method: Compositional matrix adjust.
 Identities = 40/123 (32%), Positives = 59/123 (47%), Gaps = 3/123 (2%)
 Frame = -1

Query: 210 NADVESKSGFTPLHIAA---HYGNINVATLLLNRAAAVDFTARNDITPLHVASKRGNANM 266
           + D+   +  T LH A    HYG ++    LL   A          TPL  A+ RG  ++
Sbjct: 942 DVDMRDSNDMTALHHACAGLHYGCVHA---LLQGGANPTCMEMGGKTPLFYAAHRGEISI 772

Query: 267 VKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRSAPILSKTKNGLSPLHMATQ 326
            KLL+D+GA ++A  +  +TPL   AR G+ + VE LL R A   +  + G   L+ A  
Sbjct: 771 CKLLVDKGANVNAADKMLITPLMVAAREGNREAVEFLLKRGANPNTADREGHLALYYAMA 592

Query: 327 GDH 329
             H
Sbjct: 591 AGH 583

 Score = 55.1 bits (131), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 37/120 (30%), Positives = 54/120 (45%)
 Frame = -1

Query: 672 NVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNF 731
           +V++ + + +T LH A           L+  GA+       G TPL    H G I I   
Sbjct: 942 DVDMRDSNDMTALHHACAGLHYGCVHALLQGGANPTCMEMGGKTPLFYAAHRGEISICKL 763

Query: 732 LLQHSAKVNAKTKNGYTALHQAAQQGHTHIINVLLQNNASPNELTVNGNTALAIARRLGY 791
           L+   A VNA  K   T L  AA++G+   +  LL+  A+PN     G+ AL  A   G+
Sbjct: 762 LVDKGANVNAADKMLITPLMVAAREGNREAVEFLLKRGANPNTADREGHLALYYAMAAGH 583

 Score = 53.5 bits (127), Expect = 7e-07,   Method: Compositional matrix adjust.
 Identities = 32/96 (33%), Positives = 47/96 (48%)
 Frame = -1

Query: 82  NVDAATKKGNTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVRF 141
           +VD       TALH A        V  L+  GAN       G TPL+ AA    + + + 
Sbjct: 942 DVDMRDSNDMTALHHACAGLHYGCVHALLQGGANPTCMEMGGKTPLFYAAHRGEISICKL 763

Query: 142 LLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLLE 177
           L+D GA+ + A +   TPL VA ++G+ + V  LL+
Sbjct: 762 LVDKGANVNAADKMLITPLMVAAREGNREAVEFLLK 655

 Score = 51.6 bits (122), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 33/116 (28%), Positives = 57/116 (49%)
 Frame = -1

Query: 613 NGYTPLHIAAKKNQMDIATSLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLSRNAN 672
           N  T LH A          +LL+ GA+   +   G   +  AA  G + +  LL+ + AN
Sbjct: 921 NDMTALHHACAGLHYGCVHALLQGGANPTCMEMGGKTPLFYAAHRGEISICKLLVDKGAN 742

Query: 673 VNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKI 728
           VN ++K  +TPL +AA+E      E L+ +GA+ +   + G+  L+     G+ ++
Sbjct: 741 VNAADKMLITPLMVAAREGNREAVEFLLKRGANPNTADREGHLALYYAMAAGHPEL 574

 Score = 50.1 bits (118), Expect = 7e-06,   Method: Compositional matrix adjust.
 Identities = 34/116 (29%), Positives = 54/116 (46%)
 Frame = -1

Query: 382 NGFTPLHIACKKNRIRVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGAS 441
           N  T LH AC       +  LL+ GA+   +   G TP+  AA  G ++I   L+  GA+
Sbjct: 921 NDMTALHHACAGLHYGCVHALLQGGANPTCMEMGGKTPLFYAAHRGEISICKLLVDKGAN 742

Query: 442 PNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADI 497
            N  +    T L +AAR G  E V +L++ GA      ++    L+ +   G  ++
Sbjct: 741 VNAADKMLITPLMVAAREGNREAVEFLLKRGANPNTADREGHLALYYAMAAGHPEL 574

 Score = 47.0 bits (110), Expect = 6e-05,   Method: Compositional matrix adjust.
 Identities = 35/126 (27%), Positives = 57/126 (45%)
 Frame = -1

Query: 244 VDFTARNDITPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEML 303
           VD    ND+T LH A    +   V  LL  GA        G TPL   A  G   + ++L
Sbjct: 939 VDMRDSNDMTALHHACAGLHYGCVHALLQGGANPTCMEMGGKTPLFYAAHRGEISICKLL 760

Query: 304 LDRSAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHY 363
           +D+ A + +  K  ++PL +A +  +   V+ LL+     +    +   AL+ A   GH 
Sbjct: 759 VDKGANVNAADKMLITPLMVAAREGNREAVEFLLKRGANPNTADREGHLALYYAMAAGHP 580

Query: 364 KVAKVL 369
           ++ +V 
Sbjct: 579 ELREVF 562

 Score = 46.2 bits (108), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 37/127 (29%), Positives = 58/127 (45%)
 Frame = -1

Query: 44  IKNGVDVNICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQA 103
           ++ G +       G   L  A+  G + +   L+ + ANV+AA K   T L +A+  G  
Sbjct: 858 LQGGANPTCMEMGGKTPLFYAAHRGEISICKLLVDKGANVNAADKMLITPLMVAAREGNR 679

Query: 104 EVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVRFLLDNGASQSLATEDGFTPLAVA 163
           E V+ L+  GAN N   + G   LY A    H E +R +  N   Q  A+ D  +P    
Sbjct: 678 EAVEFLLKRGANPNTADREGHLALYYAMAAGHPE-LREVFANAPLQ--ASWDLRSPDKAP 508

Query: 164 LQQGHDQ 170
            Q+G ++
Sbjct: 507 TQKGTEE 487

 Score = 39.3 bits (90), Expect = 0.014,   Method: Compositional matrix adjust.
 Identities = 31/126 (24%), Positives = 50/126 (39%)
 Frame = -1

Query: 277 IDAKTRDGLTPLHCGARSGHEQVVEMLLDRSAPILSKTKNGLSPLHMATQGDHLNCVQLL 336
           +D +  + +T LH      H   V  LL   A        G +PL  A     ++  +LL
Sbjct: 939 VDMRDSNDMTALHHACAGLHYGCVHALLQGGANPTCMEMGGKTPLFYAAHRGEISICKLL 760

Query: 337 LQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKASPNAKALNGFTPLHIACKKNRI 396
           +     V+      +T L VAA  G+ +  + LL + A+PN     G   L+ A      
Sbjct: 759 VDKGANVNAADKMLITPLMVAAREGNREAVEFLLKRGANPNTADREGHLALYYAMAAGHP 580

Query: 397 RVMELL 402
            + E+ 
Sbjct: 579 ELREVF 562

 Score = 37.4 bits (85), Expect = 0.056,   Method: Compositional matrix adjust.
 Identities = 21/60 (35%), Positives = 29/60 (48%)
 Frame = -1

Query: 739 VNAKTKNGYTALHQAAQQGHTHIINVLLQNNASPNELTVNGNTALAIARRLGYISVVDTL 798
           V+ +  N  TALH A    H   ++ LLQ  A+P  + + G T L  A   G IS+   L
Sbjct: 939 VDMRDSNDMTALHHACAGLHYGCVHALLQGGANPTCMEMGGKTPLFYAAHRGEISICKLL 760
>11861
          Length = 586

 Score = 69.7 bits (169), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 49/157 (31%), Positives = 81/157 (51%), Gaps = 4/157 (2%)
 Frame = -1

Query: 618 LHIAAKKNQMDIATSLLEYGADANAVTRQGIASV-HLAAQEGHVDMVSL--LLSRNANVN 674
           LH AAK++Q DI    L +GAD N V  QG   +  +A ++ H D V++  LL R A+ +
Sbjct: 475 LHEAAKRHQWDIVDHCLTHGADINKVDEQGFTPLFRVAYKDVHPDWVAVKELLIRGADAS 296

Query: 675 LSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQ 734
            +  S    + LA ++ + +V + L+   A +    KMG TPL       N+++++F +Q
Sbjct: 295 ATESSRKPLVKLAVRKKQWDVVKALILNHADIYRPDKMGQTPLSTLITAANMEMIHFAIQ 116

Query: 735 HS-AKVNAKTKNGYTALHQAAQQGHTHIINVLLQNNA 770
           H      A   +G T LH A Q     ++  L+++ A
Sbjct: 115 HCPGMAGAVDMSGQTILHVACQLQRPDLLQXLIKDGA 5

 Score = 57.0 bits (136), Expect = 6e-08,   Method: Compositional matrix adjust.
 Identities = 45/157 (28%), Positives = 74/157 (47%), Gaps = 4/157 (2%)
 Frame = -1

Query: 387 LHIACKKNRIRVMELLLKHGASIQAVTESGLTPIHVAAFMG-HVNIVS--QLMHHGASPN 443
           LH A K+++  +++  L HGA I  V E G TP+   A+   H + V+  +L+  GA  +
Sbjct: 475 LHEAAKRHQWDIVDHCLTHGADINKVDEQGFTPLFRVAYKDVHPDWVAVKELLIRGADAS 296

Query: 444 TTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQ 503
            T    +  + +A R  Q +VV+ L+ + A +    K  QTPL         +++   +Q
Sbjct: 295 ATESSRKPLVKLAVRKKQWDVVKALILNHADIYRPDKMGQTPLSTLITAANMEMIHFAIQ 116

Query: 504 QG-ASPNAATTSGYTPLHLAAREGHEDVAAFLLDHGA 539
                  A   SG T LH+A +    D+   L+  GA
Sbjct: 115 HCPGMAGAVDMSGQTILHVACQLQRPDLLQXLIKDGA 5

 Score = 49.3 bits (116), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 48/163 (29%), Positives = 72/163 (44%), Gaps = 9/163 (5%)
 Frame = -1

Query: 452 ALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADI------VQQLLQQG 505
           ALH AA+  Q ++V + +  GA +    +   TPL    R+   D+      V++LL +G
Sbjct: 478 ALHEAAKRHQWDIVDHCLTHGADINKVDEQGFTPLF---RVAYKDVHPDWVAVKELLIRG 308

Query: 506 ASPNAATTSGYTPLHLAAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVAS 565
           A  +A  +S    + LA R+   DV   L+ + A +    K G TPL        +E+  
Sbjct: 307 ADASATESSRKPLVKLAVRKKQWDVVKALILNHADIYRPDKMGQTPLSTLITAANMEMIH 128

Query: 566 LLLQKSASPDAAGK---SGLTPLHVAAHYDNQKVALLLLDQGA 605
             +Q    P  AG    SG T LHVA       +   L+  GA
Sbjct: 127 FAIQH--CPGMAGAVDMSGQTILHVACQLQRPDLLQXLIKDGA 5

 Score = 47.4 bits (111), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 50/190 (26%), Positives = 77/190 (40%), Gaps = 7/190 (3%)
 Frame = -1

Query: 93  ALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQEN---HLEVVRFLLDNGASQ 149
           ALH A+   Q ++V   +T+GA++N   + GFTPL+  A ++       V+ LL  GA  
Sbjct: 478 ALHEAAKRHQWDIVDHCLTHGADINKVDEQGFTPLFRVAYKDVHPDWVAVKELLIRGADA 299

Query: 150 SLATEDGFTPLAVALQQGHDQVVSLLLENDTKGKVRLPALHIAARKDDTKAAALLLQNDT 209
           S ATE                              R P + +A RK        L+ N  
Sbjct: 298 S-ATESS----------------------------RKPLVKLAVRKKQWDVVKALILNHA 206

Query: 210 NADVESKSGFTPLHIAAHYGNINVATLLLNR----AAAVDFTARNDITPLHVASKRGNAN 265
           +     K G TPL       N+ +    +      A AVD + +   T LHVA +    +
Sbjct: 205 DIYRPDKMGQTPLSTLITAANMEMIHFAIQHCPGMAGAVDMSGQ---TILHVACQLQRPD 35

Query: 266 MVKLLLDRGA 275
           +++ L+  GA
Sbjct: 34  LLQXLIKDGA 5

 Score = 45.1 bits (105), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 37/139 (26%), Positives = 67/139 (48%), Gaps = 4/139 (2%)
 Frame = -1

Query: 44  IKNGVDVNICNQNGLNAL-HLASKEGHVEVVS--ELLQREANVDAATKKGNTALHIASLA 100
           + +G D+N  ++ G   L  +A K+ H + V+  ELL R A+  A        + +A   
Sbjct: 427 LTHGADINKVDEQGFTPLFRVAYKDVHPDWVAVKELLIRGADASATESSRKPLVKLAVRK 248

Query: 101 GQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVRFLLDNGASQSLATE-DGFTP 159
            Q +VVK L+ N A++    + G TPL       ++E++ F + +    + A +  G T 
Sbjct: 247 KQWDVVKALILNHADIYRPDKMGQTPLSTLITAANMEMIHFAIQHCPGMAGAVDMSGQTI 68

Query: 160 LAVALQQGHDQVVSLLLEN 178
           L VA Q     ++  L+++
Sbjct: 67  LHVACQLQRPDLLQXLIKD 11

 Score = 44.3 bits (103), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 45/160 (28%), Positives = 72/160 (45%), Gaps = 6/160 (3%)
 Frame = -1

Query: 353 ALHVAAHCGHYKVAKVLLDKKASPNAKALNGFTPLHIACKK----NRIRVMELLLKHGAS 408
           ALH AA    + +    L   A  N     GFTPL     K    + + V ELL++ GA 
Sbjct: 478 ALHEAAKRHQWDIVDHCLTHGADINKVDEQGFTPLFRVAYKDVHPDWVAVKELLIR-GAD 302

Query: 409 IQAVTESGLTP-IHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRY 467
             A TES   P + +A      ++V  L+ + A     +  G+T L     +   E++ +
Sbjct: 301 ASA-TESSRKPLVKLAVRKKQWDVVKALILNHADIYRPDKMGQTPLSTLITAANMEMIHF 125

Query: 468 LVQDG-AQVEAKAKDDQTPLHISARLGKADIVQQLLQQGA 506
            +Q       A     QT LH++ +L + D++Q L++ GA
Sbjct: 124 AIQHCPGMAGAVDMSGQTILHVACQLQRPDLLQXLIKDGA 5

 Score = 43.1 bits (100), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 43/187 (22%), Positives = 71/187 (37%), Gaps = 1/187 (0%)
 Frame = -1

Query: 519 LHLAAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVASLLLQKSASPDAAG 578
           LH AA+    D+    L HGA ++   ++GFTPL   A             K   PD   
Sbjct: 475 LHEAAKRHQWDIVDHCLTHGADINKVDEQGFTPLFRVA------------YKDVHPDWVA 332

Query: 579 KSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATSLLEYGA 638
                                LL +GA   A   +    + +A +K Q D+  +L+   A
Sbjct: 331 VKE------------------LLIRGADASATESSRKPLVKLAVRKKQWDVVKALILNHA 206

Query: 639 DANAVTRQGIASVHLAAQEGHVDMVSLLLSRNANV-NLSNKSGLTPLHLAAQEDRVNVAE 697
           D     + G   +       +++M+   +     +    + SG T LH+A Q  R ++ +
Sbjct: 205 DIYRPDKMGQTPLSTLITAANMEMIHFAIQHCPGMAGAVDMSGQTILHVACQLQRPDLLQ 26

Query: 698 VLVNQGA 704
            L+  GA
Sbjct: 25  XLIKDGA 5

 Score = 38.5 bits (88), Expect = 0.021,   Method: Compositional matrix adjust.
 Identities = 46/165 (27%), Positives = 76/165 (46%), Gaps = 12/165 (7%)
 Frame = -1

Query: 255 LHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQV------VEMLLDRSA 308
           LH A+KR   ++V   L  GA I+     G TPL    R  ++ V      V+ LL R A
Sbjct: 475 LHEAAKRHQWDIVDHCLTHGADINKVDEQGFTPLF---RVAYKDVHPDWVAVKELLIRGA 305

Query: 309 PILSKTKNGLSPL-HMATQGDHLNCVQLLLQHNVPV---DDVTNDYLTALHVAAHCG--H 362
              S T++   PL  +A +    + V+ L+ ++  +   D +    L+ L  AA+    H
Sbjct: 304 DA-SATESSRKPLVKLAVRKKQWDVVKALILNHADIYRPDKMGQTPLSTLITAANMEMIH 128

Query: 363 YKVAKVLLDKKASPNAKALNGFTPLHIACKKNRIRVMELLLKHGA 407
           + +            A  ++G T LH+AC+  R  +++ L+K GA
Sbjct: 127 FAIQHC----PGMAGAVDMSGQTILHVACQLQRPDLLQXLIKDGA 5
>34789
          Length = 1249

 Score = 67.8 bits (164), Expect = 4e-11,   Method: Compositional matrix adjust.
 Identities = 47/158 (29%), Positives = 75/158 (47%)
 Frame = +3

Query: 449 GETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASP 508
           G TAL MA   G  E+V YL+++GA     ++     LH +       ++Q+ L  G   
Sbjct: 78  GSTALFMAVYDGNVELVDYLLKNGANPHFSSQHGNF-LHAAVLSQSVPLIQRALDLGCDI 254

Query: 509 NAATTSGYTPLHLAAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVASLLL 568
           N     G +PL L +R    +    L++HGA L+   +   TPL  +  +G    A LL+
Sbjct: 255 NEHNMFGNSPLTLVSRLDLPEACRMLVEHGADLNSRDRYRETPLLASVYFGCELNARLLI 434

Query: 569 QKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGAS 606
           Q  AS D    +  + ++ +   + Q+  +LLL  GAS
Sbjct: 435 QHGASLDLVDDNHTSAIYWSIFNNRQRTLMLLLLAGAS 548

 Score = 55.8 bits (133), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 41/166 (24%), Positives = 76/166 (45%)
 Frame = +3

Query: 377 NAKALNGFTPLHIACKKNRIRVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLM 436
           N    +G T L +A     + +++ LLK+GA+    ++ G   +H A     V ++ + +
Sbjct: 60  NQMGSDGSTALFMAVYDGNVELVDYLLKNGANPHFSSQHG-NFLHAAVLSQSVPLIQRAL 236

Query: 437 HHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKAD 496
             G   N  N+ G + L + +R    E  R LV+ GA + ++ +  +TPL  S   G   
Sbjct: 237 DLGCDINEHNMFGNSPLTLVSRLDLPEACRMLVEHGADLNSRDRYRETPLLASVYFGCEL 416

Query: 497 IVQQLLQQGASPNAATTSGYTPLHLAAREGHEDVAAFLLDHGASLS 542
             + L+Q GAS +    +  + ++ +     +     LL  GAS +
Sbjct: 417 NARLLIQHGASLDLVDDNHTSAIYWSIFNNRQRTLMLLLLAGASFT 554

 Score = 52.0 bits (123), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 44/189 (23%), Positives = 80/189 (42%)
 Frame = +3

Query: 583 TPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATSLLEYGADANA 642
           T  H  AH+ NQ                  +G T L +A     +++   LL+ GA+ + 
Sbjct: 30  TKCHSVAHFLNQ---------------MGSDGSTALFMAVYDGNVELVDYLLKNGANPHF 164

Query: 643 VTRQGIASVHLAAQEGHVDMVSLLLSRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQ 702
            ++ G   +H A     V ++   L    ++N  N  G +PL L ++ D      +LV  
Sbjct: 165 SSQHG-NFLHAAVLSQSVPLIQRALDLGCDINEHNMFGNSPLTLVSRLDLPEACRMLVEH 341

Query: 703 GAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTALHQAAQQGHTHII 762
           GA ++++ +   TPL    ++G       L+QH A ++    N  +A++ +        +
Sbjct: 342 GADLNSRDRYRETPLLASVYFGCELNARLLIQHGASLDLVDDNHTSAIYWSIFNNRQRTL 521

Query: 763 NVLLQNNAS 771
            +LL   AS
Sbjct: 522 MLLLLAGAS 548

 Score = 49.3 bits (116), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 40/159 (25%), Positives = 75/159 (47%), Gaps = 4/159 (2%)
 Frame = +3

Query: 22  SDANASYLRAARAGHLEKALDYIKNGVDVNICNQNGLNALHLASKEGHVEVVSELLQREA 81
           SD + +   A   G++E     +KNG + +  +Q+G N LH A     V ++   L    
Sbjct: 72  SDGSTALFMAVYDGNVELVDYLLKNGANPHFSSQHG-NFLHAAVLSQSVPLIQRALDLGC 248

Query: 82  NVDAATKKGNTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPL----YMAAQENHLE 137
           +++     GN+ L + S     E  ++LV +GA++N++ +   TPL    Y   + N   
Sbjct: 249 DINEHNMFGNSPLTLVSRLDLPEACRMLVEHGADLNSRDRYRETPLLASVYFGCELN--- 419

Query: 138 VVRFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLL 176
             R L+ +GAS  L  ++  + +  ++     + + LLL
Sbjct: 420 -ARLLIQHGASLDLVDDNHTSAIYWSIFNNRQRTLMLLL 533

 Score = 44.7 bits (104), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 38/160 (23%), Positives = 70/160 (43%)
 Frame = +3

Query: 479 AKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLAAREGHEDVAAFLLDHG 538
             D  T L ++   G  ++V  LL+ GA+P+ ++  G   LH A       +    LD G
Sbjct: 69  GSDGSTALFMAVYDGNVELVDYLLKNGANPHFSSQHG-NFLHAAVLSQSVPLIQRALDLG 245

Query: 539 ASLSITTKKGFTPLHVAAKYGKLEVASLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVAL 598
             ++     G +PL + ++    E   +L++  A  ++  +   TPL  + ++  +  A 
Sbjct: 246 CDINEHNMFGNSPLTLVSRLDLPEACRMLVEHGADLNSRDRYRETPLLASVYFGCELNAR 425

Query: 599 LLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATSLLEYGA 638
           LL+  GAS      N  + ++ +   N+      LL  GA
Sbjct: 426 LLIQHGASLDLVDDNHTSAIYWSIFNNRQRTLMLLLLAGA 545

 Score = 42.0 bits (97), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 41/157 (26%), Positives = 68/157 (43%)
 Frame = +3

Query: 253 TPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRSAPILS 312
           T L +A   GN  +V  LL  GA     ++ G   LH    S    +++  LD    I  
Sbjct: 84  TALFMAVYDGNVELVDYLLKNGANPHFSSQHG-NFLHAAVLSQSVPLIQRALDLGCDINE 260

Query: 313 KTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDK 372
               G SPL + ++ D     ++L++H   ++       T L  + + G    A++L+  
Sbjct: 261 HNMFGNSPLTLVSRLDLPEACRMLVEHGADLNSRDRYRETPLLASVYFGCELNARLLIQH 440

Query: 373 KASPNAKALNGFTPLHIACKKNRIRVMELLLKHGASI 409
            AS +    N  + ++ +   NR R + LLL  GAS 
Sbjct: 441 GASLDLVDDNHTSAIYWSIFNNRQRTLMLLLLAGASF 551

 Score = 33.5 bits (75), Expect = 0.70,   Method: Compositional matrix adjust.
 Identities = 39/191 (20%), Positives = 75/191 (39%)
 Frame = +3

Query: 283 DGLTPLHCGARSGHEQVVEMLLDRSAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVP 342
           DG T L      G+ ++V+ LL          KNG +P   +  G+ L+    +L  +VP
Sbjct: 75  DGSTALFMAVYDGNVELVDYLL----------KNGANPHFSSQHGNFLHAA--VLSQSVP 218

Query: 343 VDDVTNDYLTALHVAAHCGHYKVAKVLLDKKASPNAKALNGFTPLHIACKKNRIRVMELL 402
           +                       +  LD     N   + G +PL +  + +      +L
Sbjct: 219 L----------------------IQRALDLGCDINEHNMFGNSPLTLVSRLDLPEACRML 332

Query: 403 LKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQA 462
           ++HGA + +      TP+  + + G       L+ HGAS +  +    +A++ +  + + 
Sbjct: 333 VEHGADLNSRDRYRETPLLASVYFGCELNARLLIQHGASLDLVDDNHTSAIYWSIFNNRQ 512

Query: 463 EVVRYLVQDGA 473
             +  L+  GA
Sbjct: 513 RTLMLLLLAGA 545

 Score = 30.0 bits (66), Expect = 9.3,   Method: Compositional matrix adjust.
 Identities = 14/42 (33%), Positives = 25/42 (59%)
 Frame = +3

Query: 739 VNAKTKNGYTALHQAAQQGHTHIINVLLQNNASPNELTVNGN 780
           +N    +G TAL  A   G+  +++ LL+N A+P+  + +GN
Sbjct: 57  LNQMGSDGSTALFMAVYDGNVELVDYLLKNGANPHFSSQHGN 182
>20792
          Length = 441

 Score = 66.2 bits (160), Expect = 1e-10,   Method: Composition-based stats.
 Identities = 30/85 (35%), Positives = 47/85 (55%)
 Frame = +2

Query: 446 NVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQG 505
           N  G+  LH  A+ GQ + + +L+Q G QV+   + D TPL ++    +  ++  LL+ G
Sbjct: 68  NFEGKKPLHETAQFGQLDCMNFLLQRGVQVDCLKRADWTPLMLACTKCQLPVISLLLKHG 247

Query: 506 ASPNAATTSGYTPLHLAAREGHEDV 530
           A P      G+   H+AAREGH D+
Sbjct: 248 ADPALVNKDGWNSFHIAAREGHVDI 322

 Score = 61.6 bits (148), Expect = 3e-09,   Method: Composition-based stats.
 Identities = 37/107 (34%), Positives = 53/107 (49%), Gaps = 1/107 (0%)
 Frame = +2

Query: 524 REGHEDV-AAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVASLLLQKSASPDAAGKSGL 582
           R G  D+   F L     L I   +G  PLH  A++G+L+  + LLQ+    D   ++  
Sbjct: 2   RWGRRDLLEQFSLCDEVDLQIGNFEGKKPLHETAQFGQLDCMNFLLQRGVQVDCLKRADW 181

Query: 583 TPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDI 629
           TPL +A       V  LLL  GA P    K+G+   HIAA++  +DI
Sbjct: 182 TPLMLACTKCQLPVISLLLKHGADPALVNKDGWNSFHIAAREGHVDI 322

 Score = 60.8 bits (146), Expect = 5e-09,   Method: Composition-based stats.
 Identities = 28/96 (29%), Positives = 50/96 (52%)
 Frame = +2

Query: 667 LSRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNI 726
           L    ++ + N  G  PLH  AQ  +++    L+ +G  VD   +  +TPL + C    +
Sbjct: 38  LCDEVDLQIGNFEGKKPLHETAQFGQLDCMNFLLQRGVQVDCLKRADWTPLMLACTKCQL 217

Query: 727 KIVNFLLQHSAKVNAKTKNGYTALHQAAQQGHTHII 762
            +++ LL+H A      K+G+ + H AA++GH  I+
Sbjct: 218 PVISLLLKHGADPALVNKDGWNSFHIAAREGHVDIL 325

 Score = 59.7 bits (143), Expect = 9e-09,   Method: Composition-based stats.
 Identities = 30/83 (36%), Positives = 45/83 (54%)
 Frame = +2

Query: 581 GLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATSLLEYGADA 640
           G  PLH  A +        LL +G       +  +TPL +A  K Q+ + + LL++GAD 
Sbjct: 77  GKKPLHETAQFGQLDCMNFLLQRGVQVDCLKRADWTPLMLACTKCQLPVISLLLKHGADP 256

Query: 641 NAVTRQGIASVHLAAQEGHVDMV 663
             V + G  S H+AA+EGHVD++
Sbjct: 257 ALVNKDGWNSFHIAAREGHVDIL 325

 Score = 57.8 bits (138), Expect = 4e-08,   Method: Composition-based stats.
 Identities = 27/83 (32%), Positives = 47/83 (56%)
 Frame = +2

Query: 481 DDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLAAREGHEDVAAFLLDHGAS 540
           + + PLH +A+ G+ D +  LLQ+G   +    + +TPL LA  +    V + LL HGA 
Sbjct: 74  EGKKPLHETAQFGQLDCMNFLLQRGVQVDCLKRADWTPLMLACTKCQLPVISLLLKHGAD 253

Query: 541 LSITTKKGFTPLHVAAKYGKLEV 563
            ++  K G+   H+AA+ G +++
Sbjct: 254 PALVNKDGWNSFHIAAREGHVDI 322

 Score = 57.8 bits (138), Expect = 4e-08,   Method: Composition-based stats.
 Identities = 30/97 (30%), Positives = 46/97 (47%)
 Frame = +2

Query: 205 LQNDTNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRGNA 264
           L ++ +  + +  G  PLH  A +G ++    LL R   VD   R D TPL +A  +   
Sbjct: 38  LCDEVDLQIGNFEGKKPLHETAQFGQLDCMNFLLQRGVQVDCLKRADWTPLMLACTKCQL 217

Query: 265 NMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVE 301
            ++ LLL  GA      +DG    H  AR GH  +++
Sbjct: 218 PVISLLLKHGADPALVNKDGWNSFHIAAREGHVDILK 328

 Score = 56.6 bits (135), Expect = 9e-08,   Method: Composition-based stats.
 Identities = 38/116 (32%), Positives = 51/116 (43%)
 Frame = +2

Query: 317 GLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKASP 376
           G  PLH   Q   L+C+  LLQ  V VD +                         K+A  
Sbjct: 77  GKKPLHETAQFGQLDCMNFLLQRGVQVDCL-------------------------KRAD- 178

Query: 377 NAKALNGFTPLHIACKKNRIRVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIV 432
                  +TPL +AC K ++ V+ LLLKHGA    V + G    H+AA  GHV+I+
Sbjct: 179 -------WTPLMLACTKCQLPVISLLLKHGADPALVNKDGWNSFHIAAREGHVDIL 325

 Score = 54.3 bits (129), Expect = 4e-07,   Method: Composition-based stats.
 Identities = 33/100 (33%), Positives = 45/100 (45%), Gaps = 1/100 (1%)
 Frame = +2

Query: 491 RLGKADIVQQL-LQQGASPNAATTSGYTPLHLAAREGHEDVAAFLLDHGASLSITTKKGF 549
           R G+ D+++Q  L            G  PLH  A+ G  D   FLL  G  +    +  +
Sbjct: 2   RWGRRDLLEQFSLCDEVDLQIGNFEGKKPLHETAQFGQLDCMNFLLQRGVQVDCLKRADW 181

Query: 550 TPLHVAAKYGKLEVASLLLQKSASPDAAGKSGLTPLHVAA 589
           TPL +A    +L V SLLL+  A P    K G    H+AA
Sbjct: 182 TPLMLACTKCQLPVISLLLKHGADPALVNKDGWNSFHIAA 301

 Score = 53.9 bits (128), Expect = 5e-07,   Method: Composition-based stats.
 Identities = 24/86 (27%), Positives = 43/86 (50%)
 Frame = +2

Query: 381 LNGFTPLHIACKKNRIRVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGA 440
             G  PLH   +  ++  M  LL+ G  +  +  +  TP+ +A     + ++S L+ HGA
Sbjct: 71  FEGKKPLHETAQFGQLDCMNFLLQRGVQVDCLKRADWTPLMLACTKCQLPVISLLLKHGA 250

Query: 441 SPNTTNVRGETALHMAARSGQAEVVR 466
            P   N  G  + H+AAR G  ++++
Sbjct: 251 DPALVNKDGWNSFHIAAREGHVDILK 328

 Score = 37.0 bits (84), Expect(2) = 4e-06,   Method: Composition-based stats.
 Identities = 12/30 (40%), Positives = 24/30 (80%)
 Frame = +2

Query: 44  IKNGVDVNICNQNGLNALHLASKEGHVEVV 73
           +K+G D  + N++G N+ H+A++EGHV+++
Sbjct: 236 LKHGADPALVNKDGWNSFHIAAREGHVDIL 325

 Score = 33.9 bits (76), Expect(2) = 4e-06,   Method: Compositional matrix adjust.
 Identities = 16/36 (44%), Positives = 20/36 (55%)
 Frame = +3

Query: 108 VLVTNGANVNAQSQNGFTPLYMAAQENHLEVVRFLL 143
           +L +N    N  S N  TPL+ AA   H E VRF+L
Sbjct: 333 LLASNAGVWNVSSHNSRTPLHTAALHGHSEAVRFML 440

 Score = 51.2 bits (121), Expect = 4e-06,   Method: Composition-based stats.
 Identities = 25/89 (28%), Positives = 45/89 (50%)
 Frame = +2

Query: 80  EANVDAATKKGNTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVV 139
           E ++     +G   LH  +  GQ + +  L+  G  V+   +  +TPL +A  +  L V+
Sbjct: 47  EVDLQIGNFEGKKPLHETAQFGQLDCMNFLLQRGVQVDCLKRADWTPLMLACTKCQLPVI 226

Query: 140 RFLLDNGASQSLATEDGFTPLAVALQQGH 168
             LL +GA  +L  +DG+    +A ++GH
Sbjct: 227 SLLLKHGADPALVNKDGWNSFHIAAREGH 313

 Score = 50.8 bits (120), Expect = 5e-06,   Method: Composition-based stats.
 Identities = 27/82 (32%), Positives = 42/82 (51%)
 Frame = +2

Query: 614 GYTPLHIAAKKNQMDIATSLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLSRNANV 673
           G  PLH  A+  Q+D    LL+ G   + + R     + LA  +  + ++SLLL   A+ 
Sbjct: 77  GKKPLHETAQFGQLDCMNFLLQRGVQVDCLKRADWTPLMLACTKCQLPVISLLLKHGADP 256

Query: 674 NLSNKSGLTPLHLAAQEDRVNV 695
            L NK G    H+AA+E  V++
Sbjct: 257 ALVNKDGWNSFHIAAREGHVDI 322

 Score = 48.5 bits (114), Expect = 2e-05,   Method: Composition-based stats.
 Identities = 24/83 (28%), Positives = 44/83 (53%)
 Frame = +2

Query: 713 GYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTALHQAAQQGHTHIINVLLQNNASP 772
           G  PLH    +G +  +NFLLQ   +V+   +  +T L  A  +    +I++LL++ A P
Sbjct: 77  GKKPLHETAQFGQLDCMNFLLQRGVQVDCLKRADWTPLMLACTKCQLPVISLLLKHGADP 256

Query: 773 NELTVNGNTALAIARRLGYISVV 795
             +  +G  +  IA R G++ ++
Sbjct: 257 ALVNKDGWNSFHIAAREGHVDIL 325

 Score = 35.8 bits (81), Expect(2) = 0.001,   Method: Composition-based stats.
 Identities = 20/80 (25%), Positives = 36/80 (45%)
 Frame = +2

Query: 189 LHIAARKDDTKAAALLLQNDTNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFTA 248
           LH  A+         LLQ     D   ++ +TPL +A     + V +LLL   A      
Sbjct: 89  LHETAQFGQLDCMNFLLQRGVQVDCLKRADWTPLMLACTKCQLPVISLLLKHGADPALVN 268

Query: 249 RNDITPLHVASKRGNANMVK 268
           ++     H+A++ G+ +++K
Sbjct: 269 KDGWNSFHIAAREGHVDILK 328

 Score = 25.8 bits (55), Expect(2) = 0.001,   Method: Compositional matrix adjust.
 Identities = 11/36 (30%), Positives = 16/36 (44%)
 Frame = +3

Query: 269 LLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLL 304
           LL       +  + +  TPLH  A  GH + V  +L
Sbjct: 333 LLASNAGVWNVSSHNSRTPLHTAALHGHSEAVRFML 440

 Score = 42.0 bits (97), Expect = 0.002,   Method: Composition-based stats.
 Identities = 22/81 (27%), Positives = 38/81 (46%)
 Frame = +2

Query: 254 PLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRSAPILSK 313
           PLH  ++ G  + +  LL RG ++D   R   TPL          V+ +LL   A     
Sbjct: 86  PLHETAQFGQLDCMNFLLQRGVQVDCLKRADWTPLMLACTKCQLPVISLLLKHGADPALV 265

Query: 314 TKNGLSPLHMATQGDHLNCVQ 334
            K+G +  H+A +  H++ ++
Sbjct: 266 NKDGWNSFHIAAREGHVDILK 328

 Score = 41.6 bits (96), Expect = 0.003,   Method: Composition-based stats.
 Identities = 25/85 (29%), Positives = 37/85 (43%)
 Frame = +2

Query: 283 DGLTPLHCGARSGHEQVVEMLLDRSAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVP 342
           +G  PLH  A+ G    +  LL R   +    +   +PL +A     L  + LLL+H   
Sbjct: 74  EGKKPLHETAQFGQLDCMNFLLQRGVQVDCLKRADWTPLMLACTKCQLPVISLLLKHGAD 253

Query: 343 VDDVTNDYLTALHVAAHCGHYKVAK 367
              V  D   + H+AA  GH  + K
Sbjct: 254 PALVNKDGWNSFHIAAREGHVDILK 328

 Score = 36.2 bits (82), Expect = 0.13,   Method: Composition-based stats.
 Identities = 25/77 (32%), Positives = 36/77 (46%), Gaps = 4/77 (5%)
 Frame = +2

Query: 123 GFTPLYMAAQENHLEVVRFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLLENDTK- 181
           G  PL+  AQ   L+ + FLL  G          +TPL +A  +    V+SLLL++    
Sbjct: 77  GKKPLHETAQFGQLDCMNFLLQRGVQVDCLKRADWTPLMLACTKCQLPVISLLLKHGADP 256

Query: 182 ---GKVRLPALHIAARK 195
               K    + HIAAR+
Sbjct: 257 ALVNKDGWNSFHIAARE 307
>28494
          Length = 463

 Score = 65.5 bits (158), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 37/97 (38%), Positives = 51/97 (52%), Gaps = 1/97 (1%)
 Frame = -1

Query: 649 ASVHLAA-QEGHVDMVSLLLSRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVD 707
             V LAA   G  D V  LL R A++N +N  GLT LH A  +D +++ E LV Q A VD
Sbjct: 316 GCVFLAACSSGDRDEVKKLLERGADINTANVDGLTALHQACIDDNLDMVEFLVEQNADVD 137

Query: 708 AQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTK 744
                G+TPLH     G  +I  +LL++ A    + +
Sbjct: 136 VCDNEGWTPLHATASCGFTEIARYLLENGANGGCRQQ 26

 Score = 60.8 bits (146), Expect = 5e-09,   Method: Compositional matrix adjust.
 Identities = 33/111 (29%), Positives = 60/111 (54%)
 Frame = -1

Query: 11  KPAHRKRKGKKSDANASYLRAARAGHLEKALDYIKNGVDVNICNQNGLNALHLASKEGHV 70
           +P+ +K K +       +L A  +G  ++    ++ G D+N  N +GL ALH A  + ++
Sbjct: 349 RPSAKKVKFQDG---CVFLAACSSGDRDEVKKLLERGADINTANVDGLTALHQACIDDNL 179

Query: 71  EVVSELLQREANVDAATKKGNTALHIASLAGQAEVVKVLVTNGANVNAQSQ 121
           ++V  L+++ A+VD    +G T LH  +  G  E+ + L+ NGAN   + Q
Sbjct: 178 DMVEFLVEQNADVDVCDNEGWTPLHATASCGFTEIARYLLENGANGGCRQQ 26

 Score = 59.7 bits (143), Expect = 9e-09,   Method: Compositional matrix adjust.
 Identities = 31/85 (36%), Positives = 49/85 (57%)
 Frame = -1

Query: 64  ASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQAEVVKVLVTNGANVNAQSQNG 123
           A   G  + V +LL+R A+++ A   G TALH A +    ++V+ LV   A+V+     G
Sbjct: 298 ACSSGDRDEVKKLLERGADINTANVDGLTALHQACIDDNLDMVEFLVEQNADVDVCDNEG 119

Query: 124 FTPLYMAAQENHLEVVRFLLDNGAS 148
           +TPL+  A     E+ R+LL+NGA+
Sbjct: 118 WTPLHATASCGFTEIARYLLENGAN 44

 Score = 59.3 bits (142), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 34/98 (34%), Positives = 49/98 (50%)
 Frame = -1

Query: 423 AAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDD 482
           A   G  + V +L+  GA  NT NV G TALH A      ++V +LV+  A V+    + 
Sbjct: 298 ACSSGDRDEVKKLLERGADINTANVDGLTALHQACIDDNLDMVEFLVEQNADVDVCDNEG 119

Query: 483 QTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLH 520
            TPLH +A  G  +I + LL+ GA+        + P H
Sbjct: 118 WTPLHATASCGFTEIARYLLENGAN-GGCRQQRWGPCH 8

 Score = 58.9 bits (141), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 31/98 (31%), Positives = 49/98 (50%)
 Frame = -1

Query: 621 AAKKNQMDIATSLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLSRNANVNLSNKSG 680
           A      D    LLE GAD N     G+ ++H A  + ++DMV  L+ +NA+V++ +  G
Sbjct: 298 ACSSGDRDEVKKLLERGADINTANVDGLTALHQACIDDNLDMVEFLVEQNADVDVCDNEG 119

Query: 681 LTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLH 718
            TPLH  A      +A  L+  GA+   + +  + P H
Sbjct: 118 WTPLHATASCGFTEIARYLLENGANGGCRQQR-WGPCH 8

 Score = 57.0 bits (136), Expect = 7e-08,   Method: Compositional matrix adjust.
 Identities = 28/89 (31%), Positives = 48/89 (53%)
 Frame = -1

Query: 97  ASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVRFLLDNGASQSLATEDG 156
           A  +G  + VK L+  GA++N  + +G T L+ A  +++L++V FL++  A   +   +G
Sbjct: 298 ACSSGDRDEVKKLLERGADINTANVDGLTALHQACIDDNLDMVEFLVEQNADVDVCDNEG 119

Query: 157 FTPLAVALQQGHDQVVSLLLENDTKGKVR 185
           +TPL      G  ++   LLEN   G  R
Sbjct: 118 WTPLHATASCGFTEIARYLLENGANGGCR 32

 Score = 54.3 bits (129), Expect = 4e-07,   Method: Compositional matrix adjust.
 Identities = 30/98 (30%), Positives = 51/98 (52%)
 Frame = -1

Query: 456 AARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSG 515
           A  SG  + V+ L++ GA +     D  T LH +      D+V+ L++Q A  +     G
Sbjct: 298 ACSSGDRDEVKKLLERGADINTANVDGLTALHQACIDDNLDMVEFLVEQNADVDVCDNEG 119

Query: 516 YTPLHLAAREGHEDVAAFLLDHGASLSITTKKGFTPLH 553
           +TPLH  A  G  ++A +LL++GA+     ++ + P H
Sbjct: 118 WTPLHATASCGFTEIARYLLENGANGGCRQQR-WGPCH 8

 Score = 51.2 bits (121), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 27/84 (32%), Positives = 42/84 (50%)
 Frame = -1

Query: 390 ACKKNRIRVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRG 449
           AC       ++ LL+ GA I      GLT +H A    ++++V  L+   A  +  +  G
Sbjct: 298 ACSSGDRDEVKKLLERGADINTANVDGLTALHQACIDDNLDMVEFLVEQNADVDVCDNEG 119

Query: 450 ETALHMAARSGQAEVVRYLVQDGA 473
            T LH  A  G  E+ RYL+++GA
Sbjct: 118 WTPLHATASCGFTEIARYLLENGA 47

 Score = 50.1 bits (118), Expect = 7e-06,   Method: Compositional matrix adjust.
 Identities = 33/92 (35%), Positives = 42/92 (45%)
 Frame = -1

Query: 555 AAKYGKLEVASLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNG 614
           A   G  +    LL++ A  + A   GLT LH A   DN  +   L++Q A        G
Sbjct: 298 ACSSGDRDEVKKLLERGADINTANVDGLTALHQACIDDNLDMVEFLVEQNADVDVCDNEG 119

Query: 615 YTPLHIAAKKNQMDIATSLLEYGADANAVTRQ 646
           +TPLH  A     +IA  LLE G  AN   RQ
Sbjct: 118 WTPLHATASCGFTEIARYLLENG--ANGGCRQ 29

 Score = 44.7 bits (104), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 26/82 (31%), Positives = 41/82 (50%)
 Frame = -1

Query: 258 ASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRSAPILSKTKNG 317
           A   G+ + VK LL+RGA I+    DGLT LH      +  +VE L++++A +      G
Sbjct: 298 ACSSGDRDEVKKLLERGADINTANVDGLTALHQACIDDNLDMVEFLVEQNADVDVCDNEG 119

Query: 318 LSPLHMATQGDHLNCVQLLLQH 339
            +PLH           + LL++
Sbjct: 118 WTPLHATASCGFTEIARYLLEN 53

 Score = 42.0 bits (97), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 29/99 (29%), Positives = 44/99 (44%), Gaps = 3/99 (3%)
 Frame = -1

Query: 147 ASQSLATEDGFTPLAVALQQGHDQVVSLL---LENDTKGKVRLPALHIAARKDDTKAAAL 203
           +++ +  +DG   LA       D+V  LL    + +T     L ALH A   D+      
Sbjct: 343 SAKKVKFQDGCVFLAACSSGDRDEVKKLLERGADINTANVDGLTALHQACIDDNLDMVEF 164

Query: 204 LLQNDTNADVESKSGFTPLHIAAHYGNINVATLLLNRAA 242
           L++ + + DV    G+TPLH  A  G   +A  LL   A
Sbjct: 163 LVEQNADVDVCDNEGWTPLHATASCGFTEIARYLLENGA 47

 Score = 42.0 bits (97), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 34/129 (26%), Positives = 51/129 (39%)
 Frame = -1

Query: 280 KTRDGLTPLHCGARSGHEQVVEMLLDRSAPILSKTKNGLSPLHMATQGDHLNCVQLLLQH 339
           K +DG   L     SG    V+ LL+R A I +   +GL+ LH A   D+L+ V+ L++ 
Sbjct: 328 KFQDGCVFLA-ACSSGDRDEVKKLLERGADINTANVDGLTALHQACIDDNLDMVEFLVEQ 152

Query: 340 NVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKASPNAKALNGFTPLHIACKKNRIRVM 399
           N  VD   N+                                 G+TPLH         + 
Sbjct: 151 NADVDVCDNE---------------------------------GWTPLHATASCGFTEIA 71

Query: 400 ELLLKHGAS 408
             LL++GA+
Sbjct: 70  RYLLENGAN 44

 Score = 37.7 bits (86), Expect = 0.040,   Method: Compositional matrix adjust.
 Identities = 22/78 (28%), Positives = 34/78 (43%)
 Frame = -1

Query: 721 CHYGNIKIVNFLLQHSAKVNAKTKNGYTALHQAAQQGHTHIINVLLQNNASPNELTVNGN 780
           C  G+   V  LL+  A +N    +G TALHQA    +  ++  L++ NA  +     G 
Sbjct: 295 CSSGDRDEVKKLLERGADINTANVDGLTALHQACIDDNLDMVEFLVEQNADVDVCDNEGW 116

Query: 781 TALAIARRLGYISVVDTL 798
           T L      G+  +   L
Sbjct: 115 TPLHATASCGFTEIARYL 62
>20884
          Length = 712

 Score = 41.6 bits (96), Expect(2) = 1e-09,   Method: Composition-based stats.
 Identities = 23/54 (42%), Positives = 32/54 (59%), Gaps = 1/54 (1%)
 Frame = +2

Query: 746 GYTALHQAAQQGHTHIINVLLQNNASPNELT-VNGNTALAIARRLGYISVVDTL 798
           GYT  H A Q GH HI+ +LL+  A+ NE    +G T L +A  LGY+  ++ L
Sbjct: 551 GYTCAHLALQTGHLHILPLLLERGANINEQDGKSGRTLLHMAADLGYLQALELL 712

 Score = 41.2 bits (95), Expect(2) = 1e-09,   Method: Compositional matrix adjust.
 Identities = 22/61 (36%), Positives = 32/61 (52%)
 Frame = +1

Query: 673 VNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFL 732
           +N+ N    TPLHLA    ++ V   L+  GA ++A    G T LH+ C  G  ++V  L
Sbjct: 277 INIPNMLHQTPLHLAVATRQMWVVRRLMVAGAAMEAPDYCGNTALHIACREGMTEMVKLL 456

Query: 733 L 733
           L
Sbjct: 457 L 459

 Score = 42.4 bits (98), Expect(2) = 4e-09,   Method: Compositional matrix adjust.
 Identities = 24/60 (40%), Positives = 34/60 (56%)
 Frame = +1

Query: 443 NTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLL 502
           N  N+  +T LH+A  + Q  VVR L+  GA +EA      T LHI+ R G  ++V+ LL
Sbjct: 280 NIPNMLHQTPLHLAVATRQMWVVRRLMVAGAAMEAPDYCGNTALHIACREGMTEMVKLLL 459

 Score = 38.5 bits (88), Expect(2) = 4e-09,   Method: Composition-based stats.
 Identities = 23/54 (42%), Positives = 31/54 (57%), Gaps = 1/54 (1%)
 Frame = +2

Query: 515 GYTPLHLAAREGHEDVAAFLLDHGASLSITT-KKGFTPLHVAAKYGKLEVASLL 567
           GYT  HLA + GH  +   LL+ GA+++    K G T LH+AA  G L+   LL
Sbjct: 551 GYTCAHLALQTGHLHILPLLLERGANINEQDGKSGRTLLHMAADLGYLQALELL 712

 Score = 40.8 bits (94), Expect(2) = 3e-08,   Method: Compositional matrix adjust.
 Identities = 20/53 (37%), Positives = 31/53 (58%)
 Frame = +1

Query: 483 QTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLAAREGHEDVAAFLL 535
           QTPLH++    +  +V++L+  GA+  A    G T LH+A REG  ++   LL
Sbjct: 301 QTPLHLAVATRQMWVVRRLMVAGAAMEAPDYCGNTALHIACREGMTEMVKLLL 459

 Score = 37.0 bits (84), Expect(2) = 3e-08,   Method: Composition-based stats.
 Identities = 21/50 (42%), Positives = 32/50 (64%), Gaps = 1/50 (2%)
 Frame = +2

Query: 541 LSITTKKGFTPLHVAAKYGKLEVASLLLQKSAS-PDAAGKSGLTPLHVAA 589
           L+I   +G+T  H+A + G L +  LLL++ A+  +  GKSG T LH+AA
Sbjct: 530 LAIRNYEGYTCAHLALQTGHLHILPLLLERGANINEQDGKSGRTLLHMAA 679

 Score = 43.5 bits (101), Expect(2) = 3e-07,   Method: Composition-based stats.
 Identities = 24/55 (43%), Positives = 33/55 (60%), Gaps = 1/55 (1%)
 Frame = +2

Query: 646 QGIASVHLAAQEGHVDMVSLLLSRNANVNLSN-KSGLTPLHLAAQEDRVNVAEVL 699
           +G    HLA Q GH+ ++ LLL R AN+N  + KSG T LH+AA    +   E+L
Sbjct: 548 EGYTCAHLALQTGHLHILPLLLERGANINEQDGKSGRTLLHMAADLGYLQALELL 712

 Score = 30.8 bits (68), Expect(2) = 3e-07,   Method: Compositional matrix adjust.
 Identities = 25/92 (27%), Positives = 43/92 (46%), Gaps = 3/92 (3%)
 Frame = +1

Query: 546 KKGFTPLHVAAKYGKLEVASLLLQKSASPDAAGKSGL---TPLHVAAHYDNQKVALLLLD 602
           + G + LH++  +   +V+  ++  + SPD      +   TPLH+A       V   L+ 
Sbjct: 184 EDGDSYLHMSIIHLLPDVSLKVISVAPSPDYINIPNMLHQTPLHLAVATRQMWVVRRLMV 363

Query: 603 QGASPHAAAKNGYTPLHIAAKKNQMDIATSLL 634
            GA+  A    G T LHIA ++   ++   LL
Sbjct: 364 AGAAMEAPDYCGNTALHIACREGMTEMVKLLL 459

 Score = 33.5 bits (75), Expect(2) = 8e-05,   Method: Composition-based stats.
 Identities = 20/54 (37%), Positives = 30/54 (55%), Gaps = 1/54 (1%)
 Frame = +2

Query: 416 GLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVR-GETALHMAARSGQAEVVRYL 468
           G T  H+A   GH++I+  L+  GA+ N  + + G T LHMAA  G  + +  L
Sbjct: 551 GYTCAHLALQTGHLHILPLLLERGANINEQDGKSGRTLLHMAADLGYLQALELL 712

 Score = 32.3 bits (72), Expect(2) = 8e-05,   Method: Compositional matrix adjust.
 Identities = 30/104 (28%), Positives = 49/104 (47%), Gaps = 10/104 (9%)
 Frame = +1

Query: 310 ILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDV--TNDYL--------TALHVAAH 359
           + S+ ++G S LHM+        + LL   ++ V  V  + DY+        T LH+A  
Sbjct: 169 LYSQDEDGDSYLHMSI-------IHLLPDVSLKVISVAPSPDYINIPNMLHQTPLHLAVA 327

Query: 360 CGHYKVAKVLLDKKASPNAKALNGFTPLHIACKKNRIRVMELLL 403
                V + L+   A+  A    G T LHIAC++    +++LLL
Sbjct: 328 TRQMWVVRRLMVAGAAMEAPDYCGNTALHIACREGMTEMVKLLL 459

 Score = 36.2 bits (82), Expect(2) = 6e-04,   Method: Compositional matrix adjust.
 Identities = 19/52 (36%), Positives = 29/52 (55%)
 Frame = +1

Query: 253 TPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLL 304
           TPLH+A       +V+ L+  GA ++A    G T LH   R G  ++V++LL
Sbjct: 304 TPLHLAVATRQMWVVRRLMVAGAAMEAPDYCGNTALHIACREGMTEMVKLLL 459

 Score = 26.9 bits (58), Expect(2) = 6e-04,   Method: Composition-based stats.
 Identities = 16/54 (29%), Positives = 29/54 (53%), Gaps = 1/54 (1%)
 Frame = +2

Query: 317 GLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDY-LTALHVAAHCGHYKVAKVL 369
           G +  H+A Q  HL+ + LLL+    +++       T LH+AA  G+ +  ++L
Sbjct: 551 GYTCAHLALQTGHLHILPLLLERGANINEQDGKSGRTLLHMAADLGYLQALELL 712

 Score = 33.1 bits (74), Expect(2) = 7e-04,   Method: Compositional matrix adjust.
 Identities = 23/73 (31%), Positives = 36/73 (49%), Gaps = 5/73 (6%)
 Frame = +1

Query: 125 TPLYMAAQENHLEVVRFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLL-----END 179
           TPL++A     + VVR L+  GA+       G T L +A ++G  ++V LLL     +  
Sbjct: 304 TPLHLAVATRQMWVVRRLMVAGAAMEAPDYCGNTALHIACREGMTEMVKLLLTPVQYQET 483

Query: 180 TKGKVRLPALHIA 192
              +  LP L I+
Sbjct: 484 LANQYSLPQLTIS 522

 Score = 29.6 bits (65), Expect(2) = 7e-04,   Method: Composition-based stats.
 Identities = 17/59 (28%), Positives = 33/59 (55%), Gaps = 1/59 (1%)
 Frame = +2

Query: 213 VESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFT-ARNDITPLHVASKRGNANMVKLL 270
           + +  G+T  H+A   G++++  LLL R A ++    ++  T LH+A+  G    ++LL
Sbjct: 536 IRNYEGYTCAHLALQTGHLHILPLLLERGANINEQDGKSGRTLLHMAADLGYLQALELL 712

 Score = 43.5 bits (101), Expect = 8e-04,   Method: Compositional matrix adjust.
 Identities = 26/62 (41%), Positives = 34/62 (54%)
 Frame = +1

Query: 50  VNICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQAEVVKVL 109
           +NI N      LHLA     + VV  L+   A ++A    GNTALHIA   G  E+VK+L
Sbjct: 277 INIPNMLHQTPLHLAVATRQMWVVRRLMVAGAAMEAPDYCGNTALHIACREGMTEMVKLL 456

Query: 110 VT 111
           +T
Sbjct: 457 LT 462

 Score = 41.2 bits (95), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 20/52 (38%), Positives = 31/52 (59%)
 Frame = +1

Query: 418 TPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLV 469
           TP+H+A     + +V +LM  GA+    +  G TALH+A R G  E+V+ L+
Sbjct: 304 TPLHLAVATRQMWVVRRLMVAGAAMEAPDYCGNTALHIACREGMTEMVKLLL 459

 Score = 40.8 bits (94), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 21/53 (39%), Positives = 30/53 (56%)
 Frame = +1

Query: 616 TPLHIAAKKNQMDIATSLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLS 668
           TPLH+A    QM +   L+  GA   A    G  ++H+A +EG  +MV LLL+
Sbjct: 304 TPLHLAVATRQMWVVRRLMVAGAAMEAPDYCGNTALHIACREGMTEMVKLLLT 462

 Score = 39.7 bits (91), Expect = 0.009,   Method: Composition-based stats.
 Identities = 22/62 (35%), Positives = 36/62 (58%), Gaps = 1/62 (1%)
 Frame = +2

Query: 49  DVNICNQNGLNALHLASKEGHVEVVSELLQREANVDAAT-KKGNTALHIASLAGQAEVVK 107
           D+ I N  G    HLA + GH+ ++  LL+R AN++    K G T LH+A+  G  + ++
Sbjct: 527 DLAIRNYEGYTCAHLALQTGHLHILPLLLERGANINEQDGKSGRTLLHMAADLGYLQALE 706

Query: 108 VL 109
           +L
Sbjct: 707 LL 712

 Score = 35.8 bits (81), Expect(2) = 0.037,   Method: Composition-based stats.
 Identities = 23/62 (37%), Positives = 36/62 (58%), Gaps = 3/62 (4%)
 Frame = +2

Query: 245 DFTARN--DITPLHVASKRGNANMVKLLLDRGAKIDAKT-RDGLTPLHCGARSGHEQVVE 301
           D   RN    T  H+A + G+ +++ LLL+RGA I+ +  + G T LH  A  G+ Q +E
Sbjct: 527 DLAIRNYEGYTCAHLALQTGHLHILPLLLERGANINEQDGKSGRTLLHMAADLGYLQALE 706

Query: 302 ML 303
           +L
Sbjct: 707 LL 712

 Score = 20.8 bits (42), Expect(2) = 0.037,   Method: Compositional matrix adjust.
 Identities = 14/51 (27%), Positives = 18/51 (35%)
 Frame = +1

Query: 189 LHIAARKDDTKAAALLLQNDTNADVESKSGFTPLHIAAHYGNINVATLLLN 239
           LH+A           L+      +     G T LHIA   G   +  LLL 
Sbjct: 310 LHLAVATRQMWVVRRLMVAGAAMEAPDYCGNTALHIACREGMTEMVKLLLT 462

 Score = 36.6 bits (83), Expect = 0.082,   Method: Compositional matrix adjust.
 Identities = 29/102 (28%), Positives = 47/102 (46%), Gaps = 3/102 (2%)
 Frame = +1

Query: 470 QDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASP---NAATTSGYTPLHLAAREG 526
           Q+  ++ ++ +D  + LH+S      D+  +++    SP   N       TPLHLA    
Sbjct: 154 QELEELYSQDEDGDSYLHMSIIHLLPDVSLKVISVAPSPDYINIPNMLHQTPLHLAVATR 333

Query: 527 HEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVASLLL 568
              V   L+  GA++      G T LH+A + G  E+  LLL
Sbjct: 334 QMWVVRRLMVAGAAMEAPDYCGNTALHIACREGMTEMVKLLL 459

 Score = 35.4 bits (80), Expect = 0.19,   Method: Composition-based stats.
 Identities = 19/55 (34%), Positives = 32/55 (58%), Gaps = 1/55 (1%)
 Frame = +2

Query: 89  KGNTALHIASLAGQAEVVKVLVTNGANVNAQS-QNGFTPLYMAAQENHLEVVRFL 142
           +G T  H+A   G   ++ +L+  GAN+N Q  ++G T L+MAA   +L+ +  L
Sbjct: 548 EGYTCAHLALQTGHLHILPLLLERGANINEQDGKSGRTLLHMAADLGYLQALELL 712

 Score = 34.7 bits (78), Expect = 0.32,   Method: Compositional matrix adjust.
 Identities = 18/62 (29%), Positives = 32/62 (51%)
 Frame = +1

Query: 705 HVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTALHQAAQQGHTHIINV 764
           +++    +  TPLH+      + +V  L+   A + A    G TALH A ++G T ++ +
Sbjct: 274 YINIPNMLHQTPLHLAVATRQMWVVRRLMVAGAAMEAPDYCGNTALHIACREGMTEMVKL 453

Query: 765 LL 766
           LL
Sbjct: 454 LL 459

 Score = 29.6 bits (65), Expect(2) = 0.36,   Method: Composition-based stats.
 Identities = 17/52 (32%), Positives = 29/52 (55%), Gaps = 1/52 (1%)
 Frame = +2

Query: 352 TALHVAAHCGHYKVAKVLLDKKASPNAK-ALNGFTPLHIACKKNRIRVMELL 402
           T  H+A   GH  +  +LL++ A+ N +   +G T LH+A     ++ +ELL
Sbjct: 557 TCAHLALQTGHLHILPLLLERGANINEQDGKSGRTLLHMAADLGYLQALELL 712

 Score = 23.5 bits (49), Expect(2) = 0.36,   Method: Compositional matrix adjust.
 Identities = 16/52 (30%), Positives = 24/52 (46%)
 Frame = +1

Query: 286 TPLHCGARSGHEQVVEMLLDRSAPILSKTKNGLSPLHMATQGDHLNCVQLLL 337
           TPLH    +    VV  L+   A + +    G + LH+A +      V+LLL
Sbjct: 304 TPLHLAVATRQMWVVRRLMVAGAAMEAPDYCGNTALHIACREGMTEMVKLLL 459

 Score = 33.5 bits (75), Expect = 0.74,   Method: Composition-based stats.
 Identities = 18/54 (33%), Positives = 34/54 (62%), Gaps = 1/54 (1%)
 Frame = +2

Query: 383 GFTPLHIACKKNRIRVMELLLKHGASI-QAVTESGLTPIHVAAFMGHVNIVSQL 435
           G+T  H+A +   + ++ LLL+ GA+I +   +SG T +H+AA +G++  +  L
Sbjct: 551 GYTCAHLALQTGHLHILPLLLERGANINEQDGKSGRTLLHMAADLGYLQALELL 712

 Score = 33.1 bits (74), Expect = 0.88,   Method: Compositional matrix adjust.
 Identities = 17/52 (32%), Positives = 29/52 (55%)
 Frame = +1

Query: 385 TPLHIACKKNRIRVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLM 436
           TPLH+A    ++ V+  L+  GA+++A    G T +H+A   G   +V  L+
Sbjct: 304 TPLHLAVATRQMWVVRRLMVAGAAMEAPDYCGNTALHIACREGMTEMVKLLL 459

 Score = 32.0 bits (71), Expect = 2.3,   Method: Composition-based stats.
 Identities = 19/54 (35%), Positives = 29/54 (53%), Gaps = 1/54 (1%)
 Frame = +2

Query: 614 GYTPLHIAAKKNQMDIATSLLEYGADANAVT-RQGIASVHLAAQEGHVDMVSLL 666
           GYT  H+A +   + I   LLE GA+ N    + G   +H+AA  G++  + LL
Sbjct: 551 GYTCAHLALQTGHLHILPLLLERGANINEQDGKSGRTLLHMAADLGYLQALELL 712

 Score = 30.8 bits (68), Expect = 5.4,   Method: Composition-based stats.
 Identities = 21/55 (38%), Positives = 29/55 (52%), Gaps = 5/55 (9%)
 Frame = +2

Query: 155 DGFTPLAVALQQGHDQVVSLLLE-----NDTKGKVRLPALHIAARKDDTKAAALL 204
           +G+T   +ALQ GH  ++ LLLE     N+  GK     LH+AA     +A  LL
Sbjct: 548 EGYTCAHLALQTGHLHILPLLLERGANINEQDGKSGRTLLHMAADLGYLQALELL 712
>28113
          Length = 449

 Score = 61.6 bits (148), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 36/91 (39%), Positives = 48/91 (52%)
 Frame = -3

Query: 482 DQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLAAREGHEDVAAFLLDHGASL 541
           D+ PLH SA  G    VQ LL  G   +   +  +  +H A+  G  DV   LLD G S 
Sbjct: 333 DKYPLHASAAQGDVHHVQSLLNHGHHHSKKDSIAWAAIHYASWYGSADVVEILLDAGCSP 154

Query: 542 SITTKKGFTPLHVAAKYGKLEVASLLLQKSA 572
           ++T  +  TPLH+AAK G  +VA  L+Q  A
Sbjct: 153 NLTNSELLTPLHIAAKKGFPDVAEHLVQAEA 61

 Score = 55.5 bits (132), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 32/95 (33%), Positives = 47/95 (49%)
 Frame = -3

Query: 441 SPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQ 500
           +P     R +  LH +A  G    V+ L+  G     K       +H ++  G AD+V+ 
Sbjct: 357 NPVEPRWRDKYPLHASAAQGDVHHVQSLLNHGHHHSKKDSIAWAAIHYASWYGSADVVEI 178

Query: 501 LLQQGASPNAATTSGYTPLHLAAREGHEDVAAFLL 535
           LL  G SPN   +   TPLH+AA++G  DVA  L+
Sbjct: 177 LLDAGCSPNLTNSELLTPLHIAAKKGFPDVAEHLV 73

 Score = 53.5 bits (127), Expect = 8e-07,   Method: Compositional matrix adjust.
 Identities = 32/88 (36%), Positives = 48/88 (54%)
 Frame = -3

Query: 617 PLHIAAKKNQMDIATSLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLSRNANVNLS 676
           PLH +A +  +    SLL +G   +       A++H A+  G  D+V +LL    + NL+
Sbjct: 324 PLHASAAQGDVHHVQSLLNHGHHHSKKDSIAWAAIHYASWYGSADVVEILLDAGCSPNLT 145

Query: 677 NKSGLTPLHLAAQEDRVNVAEVLVNQGA 704
           N   LTPLH+AA++   +VAE LV   A
Sbjct: 144 NSELLTPLHIAAKKGFPDVAEHLVQAEA 61

 Score = 53.1 bits (126), Expect = 9e-07,   Method: Compositional matrix adjust.
 Identities = 29/85 (34%), Positives = 43/85 (50%)
 Frame = -3

Query: 386 PLHIACKKNRIRVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTT 445
           PLH +  +  +  ++ LL HG             IH A++ G  ++V  L+  G SPN T
Sbjct: 324 PLHASAAQGDVHHVQSLLNHGHHHSKKDSIAWAAIHYASWYGSADVVEILLDAGCSPNLT 145

Query: 446 NVRGETALHMAARSGQAEVVRYLVQ 470
           N    T LH+AA+ G  +V  +LVQ
Sbjct: 144 NSELLTPLHIAAKKGFPDVAEHLVQ 70

 Score = 51.2 bits (121), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 29/88 (32%), Positives = 46/88 (52%)
 Frame = -3

Query: 419 PIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAK 478
           P+H +A  G V+ V  L++HG   +  +     A+H A+  G A+VV  L+  G      
Sbjct: 324 PLHASAAQGDVHHVQSLLNHGHHHSKKDSIAWAAIHYASWYGSADVVEILLDAGCSPNLT 145

Query: 479 AKDDQTPLHISARLGKADIVQQLLQQGA 506
             +  TPLHI+A+ G  D+ + L+Q  A
Sbjct: 144 NSELLTPLHIAAKKGFPDVAEHLVQAEA 61

 Score = 47.0 bits (110), Expect = 7e-05,   Method: Compositional matrix adjust.
 Identities = 26/72 (36%), Positives = 36/72 (50%)
 Frame = -3

Query: 518 PLHLAAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVASLLLQKSASPDAA 577
           PLH +A +G       LL+HG   S      +  +H A+ YG  +V  +LL    SP+  
Sbjct: 324 PLHASAAQGDVHHVQSLLNHGHHHSKKDSIAWAAIHYASWYGSADVVEILLDAGCSPNLT 145

Query: 578 GKSGLTPLHVAA 589
               LTPLH+AA
Sbjct: 144 NSELLTPLHIAA 109

 Score = 46.2 bits (108), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 33/98 (33%), Positives = 44/98 (44%), Gaps = 1/98 (1%)
 Frame = -3

Query: 551 PLHVAAKYGKLEVASLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAA 610
           PLH +A  G +     LL                +H A+ Y +  V  +LLD G SP+  
Sbjct: 324 PLHASAAQGDVHHVQSLLNHGHHHSKKDSIAWAAIHYASWYGSADVVEILLDAGCSPNLT 145

Query: 611 AKNGYTPLHIAAKKNQMDIATSLLEYGA-DANAVTRQG 647
                TPLHIAAKK   D+A  L++  A D N   + G
Sbjct: 144 NSELLTPLHIAAKKGFPDVAEHLVQAEAIDLNLRDKDG 31

 Score = 46.2 bits (108), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 33/108 (30%), Positives = 52/108 (48%), Gaps = 1/108 (0%)
 Frame = -3

Query: 221 PLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRGNANMVKLLLDRGAKIDAK 280
           PLH +A  G+++    LLN               +H AS  G+A++V++LLD G   +  
Sbjct: 324 PLHASAAQGDVHHVQSLLNHGHHHSKKDSIAWAAIHYASWYGSADVVEILLDAGCSPNLT 145

Query: 281 TRDGLTPLHCGARSGHEQVVEMLLDRSAPILS-KTKNGLSPLHMATQG 327
             + LTPLH  A+ G   V E L+   A  L+ + K+G   + + T  
Sbjct: 144 NSELLTPLHIAAKKGFPDVAEHLVQAEAIDLNLRDKDGKRAIDICTSA 1

 Score = 44.3 bits (103), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 34/86 (39%), Positives = 43/86 (50%), Gaps = 1/86 (1%)
 Frame = -3

Query: 320 PLHM-ATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKASPNA 378
           PLH  A QGD ++ VQ LL H        +    A+H A+  G   V ++LLD   SPN 
Sbjct: 324 PLHASAAQGD-VHHVQSLLNHGHHHSKKDSIAWAAIHYASWYGSADVVEILLDAGCSPNL 148

Query: 379 KALNGFTPLHIACKKNRIRVMELLLK 404
                 TPLHIA KK    V E L++
Sbjct: 147 TNSELLTPLHIAAKKGFPDVAEHLVQ 70

 Score = 43.9 bits (102), Expect = 6e-04,   Method: Compositional matrix adjust.
 Identities = 26/95 (27%), Positives = 49/95 (51%)
 Frame = -3

Query: 189 LHIAARKDDTKAAALLLQNDTNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFTA 248
           LH +A + D      LL +  +   +    +  +H A+ YG+ +V  +LL+   + + T 
Sbjct: 321 LHASAAQGDVHHVQSLLNHGHHHSKKDSIAWAAIHYASWYGSADVVEILLDAGCSPNLTN 142

Query: 249 RNDITPLHVASKRGNANMVKLLLDRGAKIDAKTRD 283
              +TPLH+A+K+G  ++ + L+ +   ID   RD
Sbjct: 141 SELLTPLHIAAKKGFPDVAEHLV-QAEAIDLNLRD 40

 Score = 42.0 bits (97), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 25/83 (30%), Positives = 42/83 (50%)
 Frame = -3

Query: 61  LHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQAEVVKVLVTNGANVNAQS 120
           LH ++ +G V  V  LL    +          A+H AS  G A+VV++L+  G + N  +
Sbjct: 321 LHASAAQGDVHHVQSLLNHGHHHSKKDSIAWAAIHYASWYGSADVVEILLDAGCSPNLTN 142

Query: 121 QNGFTPLYMAAQENHLEVVRFLL 143
               TPL++AA++   +V   L+
Sbjct: 141 SELLTPLHIAAKKGFPDVAEHLV 73

 Score = 41.6 bits (96), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 25/83 (30%), Positives = 37/83 (44%)
 Frame = -3

Query: 716 PLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTALHQAAQQGHTHIINVLLQNNASPNEL 775
           PLH     G++  V  LL H    + K    + A+H A+  G   ++ +LL    SPN  
Sbjct: 324 PLHASAAQGDVHHVQSLLNHGHHHSKKDSIAWAAIHYASWYGSADVVEILLDAGCSPNLT 145

Query: 776 TVNGNTALAIARRLGYISVVDTL 798
                T L IA + G+  V + L
Sbjct: 144 NSELLTPLHIAAKKGFPDVAEHL 76

 Score = 40.0 bits (92), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 27/89 (30%), Positives = 47/89 (52%), Gaps = 1/89 (1%)
 Frame = -3

Query: 251 DITPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDR-SAP 309
           D  PLH ++ +G+ + V+ LL+ G     K       +H  +  G   VVE+LLD   +P
Sbjct: 333 DKYPLHASAAQGDVHHVQSLLNHGHHHSKKDSIAWAAIHYASWYGSADVVEILLDAGCSP 154

Query: 310 ILSKTKNGLSPLHMATQGDHLNCVQLLLQ 338
            L+ ++  L+PLH+A +    +  + L+Q
Sbjct: 153 NLTNSEL-LTPLHIAAKKGFPDVAEHLVQ 70

 Score = 39.7 bits (91), Expect = 0.012,   Method: Compositional matrix adjust.
 Identities = 22/84 (26%), Positives = 42/84 (50%)
 Frame = -3

Query: 94  LHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVRFLLDNGASQSLAT 153
           LH ++  G    V+ L+ +G + + +    +  ++ A+     +VV  LLD G S +L  
Sbjct: 321 LHASAAQGDVHHVQSLLNHGHHHSKKDSIAWAAIHYASWYGSADVVEILLDAGCSPNLTN 142

Query: 154 EDGFTPLAVALQQGHDQVVSLLLE 177
            +  TPL +A ++G   V   L++
Sbjct: 141 SELLTPLHIAAKKGFPDVAEHLVQ 70

 Score = 33.1 bits (74), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 28/96 (29%), Positives = 43/96 (44%), Gaps = 4/96 (4%)
 Frame = -3

Query: 159 PLAVALQQGHDQVVSLLL----ENDTKGKVRLPALHIAARKDDTKAAALLLQNDTNADVE 214
           PL  +  QG    V  LL     +  K  +   A+H A+         +LL    + ++ 
Sbjct: 324 PLHASAAQGDVHHVQSLLNHGHHHSKKDSIAWAAIHYASWYGSADVVEILLDAGCSPNLT 145

Query: 215 SKSGFTPLHIAAHYGNINVATLLLNRAAAVDFTARN 250
           +    TPLHIAA  G  +VA  L+ +A A+D   R+
Sbjct: 144 NSELLTPLHIAAKKGFPDVAEHLV-QAEAIDLNLRD 40

 Score = 32.0 bits (71), Expect = 2.1,   Method: Compositional matrix adjust.
 Identities = 23/83 (27%), Positives = 36/83 (43%)
 Frame = -3

Query: 354 LHVAAHCGHYKVAKVLLDKKASPNAKALNGFTPLHIACKKNRIRVMELLLKHGASIQAVT 413
           LH +A  G     + LL+     + K    +  +H A       V+E+LL  G S     
Sbjct: 321 LHASAAQGDVHHVQSLLNHGHHHSKKDSIAWAAIHYASWYGSADVVEILLDAGCSPNLTN 142

Query: 414 ESGLTPIHVAAFMGHVNIVSQLM 436
              LTP+H+AA  G  ++   L+
Sbjct: 141 SELLTPLHIAAKKGFPDVAEHLV 73
>09180
          Length = 610

 Score = 60.5 bits (145), Expect = 7e-09,   Method: Compositional matrix adjust.
 Identities = 41/139 (29%), Positives = 61/139 (43%)
 Frame = +3

Query: 466 RYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLAARE 525
           R+L     +  A  K   T LH+SA  G  +++  LLQ G   NA    G+T LH A   
Sbjct: 117 RWLQNKNIEDNAHPKTGATALHVSAAKGYINVMNVLLQAGVDINAQDADGWTSLHAAVHW 296

Query: 526 GHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVASLLLQKSASPDAAGKSGLTPL 585
           G ED    L+DH   + +    G T   +A K   L+V   L +K A    A +S    +
Sbjct: 297 GQEDSCQVLVDHFCDMDVKNNAGHTVFDLADKE-MLKVLEELKKKQAKLRTASESNSDII 473

Query: 586 HVAAHYDNQKVALLLLDQG 604
           H   H   ++ ++  +  G
Sbjct: 474 HTPGHGSKRRSSVTRMSSG 530

 Score = 54.3 bits (129), Expect = 4e-07,   Method: Compositional matrix adjust.
 Identities = 28/90 (31%), Positives = 44/90 (48%)
 Frame = +3

Query: 661 DMVSLLLSRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVG 720
           D    L ++N   N   K+G T LH++A +  +NV  VL+  G  ++AQ   G+T LH  
Sbjct: 108 DANRWLQNKNIEDNAHPKTGATALHVSAAKGYINVMNVLLQAGVDINAQDADGWTSLHAA 287

Query: 721 CHYGNIKIVNFLLQHSAKVNAKTKNGYTAL 750
            H+G       L+ H   ++ K   G+T  
Sbjct: 288 VHWGQEDSCQVLVDHFCDMDVKNNAGHTVF 377

 Score = 51.6 bits (122), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 33/108 (30%), Positives = 53/108 (49%)
 Frame = +3

Query: 315 KNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKA 374
           K G + LH++    ++N + +LLQ  V ++    D  T+LH A H G     +VL+D   
Sbjct: 159 KTGATALHVSAAKGYINVMNVLLQAGVDINAQDADGWTSLHAAVHWGQEDSCQVLVDHFC 338

Query: 375 SPNAKALNGFTPLHIACKKNRIRVMELLLKHGASIQAVTESGLTPIHV 422
             + K   G T   +A  K  ++V+E L K  A ++  +ES    IH 
Sbjct: 339 DMDVKNNAGHTVFDLA-DKEMLKVLEELKKKQAKLRTASESNSDIIHT 479

 Score = 48.5 bits (114), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 31/101 (30%), Positives = 49/101 (48%)
 Frame = +3

Query: 699 LVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTALHQAAQQGH 758
           L N+    +A  K G T LHV    G I ++N LLQ    +NA+  +G+T+LH A   G 
Sbjct: 123 LQNKNIEDNAHPKTGATALHVSAAKGYINVMNVLLQAGVDINAQDADGWTSLHAAVHWGQ 302

Query: 759 THIINVLLQNNASPNELTVNGNTALAIARRLGYISVVDTLK 799
                VL+ +    +     G+T   +A +   + V++ LK
Sbjct: 303 EDSCQVLVDHFCDMDVKNNAGHTVFDLADK-EMLKVLEELK 422

 Score = 48.1 bits (113), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 28/92 (30%), Positives = 46/92 (50%)
 Frame = +3

Query: 599 LLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATSLLEYGADANAVTRQGIASVHLAAQEG 658
            L ++    +A  K G T LH++A K  +++   LL+ G D NA    G  S+H A   G
Sbjct: 120 WLQNKNIEDNAHPKTGATALHVSAAKGYINVMNVLLQAGVDINAQDADGWTSLHAAVHWG 299

Query: 659 HVDMVSLLLSRNANVNLSNKSGLTPLHLAAQE 690
             D   +L+    ++++ N +G T   LA +E
Sbjct: 300 QEDSCQVLVDHFCDMDVKNNAGHTVFDLADKE 395

 Score = 46.2 bits (108), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 28/98 (28%), Positives = 57/98 (58%), Gaps = 1/98 (1%)
 Frame = +3

Query: 37  LEKALDYIKN-GVDVNICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKGNTALH 95
           +E A  +++N  ++ N   + G  ALH+++ +G++ V++ LLQ   +++A    G T+LH
Sbjct: 102 MEDANRWLQNKNIEDNAHPKTGATALHVSAAKGYINVMNVLLQAGVDINAQDADGWTSLH 281

Query: 96  IASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQE 133
            A   GQ +  +VLV +  +++ ++  G T   +A +E
Sbjct: 282 AAVHWGQEDSCQVLVDHFCDMDVKNNAGHTVFDLADKE 395

 Score = 45.1 bits (105), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 25/79 (31%), Positives = 37/79 (46%)
 Frame = +3

Query: 546 KKGFTPLHVAAKYGKLEVASLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGA 605
           K G T LHV+A  G + V ++LLQ     +A    G T LH A H+  +    +L+D   
Sbjct: 159 KTGATALHVSAAKGYINVMNVLLQAGVDINAQDADGWTSLHAAVHWGQEDSCQVLVDHFC 338

Query: 606 SPHAAAKNGYTPLHIAAKK 624
                   G+T   +A K+
Sbjct: 339 DMDVKNNAGHTVFDLADKE 395

 Score = 44.3 bits (103), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 35/128 (27%), Positives = 60/128 (46%), Gaps = 1/128 (0%)
 Frame = +3

Query: 37  LEKALDYIKNGVDVNICNQNGLNALHLASKEGHVEVVSELLQREANVDAAT-KKGNTALH 95
           L+K +D  K GVD +   +   + +        +E  +  LQ +   D A  K G TALH
Sbjct: 33  LQKEMD--KKGVDADAARKEEEDMM--------MEDANRWLQNKNIEDNAHPKTGATALH 182

Query: 96  IASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVRFLLDNGASQSLATED 155
           +++  G   V+ VL+  G ++NAQ  +G+T L+ A      +  + L+D+     +    
Sbjct: 183 VSAAKGYINVMNVLLQAGVDINAQDADGWTSLHAAVHWGQEDSCQVLVDHFCDMDVKNNA 362

Query: 156 GFTPLAVA 163
           G T   +A
Sbjct: 363 GHTVFDLA 386

 Score = 42.7 bits (99), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 29/114 (25%), Positives = 56/114 (49%), Gaps = 4/114 (3%)
 Frame = +3

Query: 415 SGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQ 474
           +G T +HV+A  G++N+++ L+  G   N  +  G T+LH A   GQ +  + LV     
Sbjct: 162 TGATALHVSAAKGYINVMNVLLQAGVDINAQDADGWTSLHAAVHWGQEDSCQVLVDHFCD 341

Query: 475 VEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSG----YTPLHLAAR 524
           ++ K     T   ++ +     ++++L ++ A    A+ S     +TP H + R
Sbjct: 342 MDVKNNAGHTVFDLADK-EMLKVLEELKKKQAKLRTASESNSDIIHTPGHGSKR 500

 Score = 42.0 bits (97), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 42/143 (29%), Positives = 66/143 (46%), Gaps = 7/143 (4%)
 Frame = +3

Query: 192 AARKDD----TKAAALLLQNDTNAD-VESKSGFTPLHIAAHYGNINVATLLLNRAAAVDF 246
           AARK++     + A   LQN    D    K+G T LH++A  G INV  +LL   A VD 
Sbjct: 72  AARKEEEDMMMEDANRWLQNKNIEDNAHPKTGATALHVSAAKGYINVMNVLLQ--AGVDI 245

Query: 247 TAR--NDITPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLL 304
            A+  +  T LH A   G  +  ++L+D    +D K   G T      +    +V+E L 
Sbjct: 246 NAQDADGWTSLHAAVHWGQEDSCQVLVDHFCDMDVKNNAGHTVFDLADKE-MLKVLEELK 422

Query: 305 DRSAPILSKTKNGLSPLHMATQG 327
            + A + + +++    +H    G
Sbjct: 423 KKQAKLRTASESNSDIIHTPGHG 491

 Score = 38.1 bits (87), Expect = 0.029,   Method: Compositional matrix adjust.
 Identities = 31/98 (31%), Positives = 46/98 (46%), Gaps = 1/98 (1%)
 Frame = +3

Query: 561 LEVASLLLQ-KSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLH 619
           +E A+  LQ K+   +A  K+G T LHV+A      V  +LL  G   +A   +G+T LH
Sbjct: 102 MEDANRWLQNKNIEDNAHPKTGATALHVSAAKGYINVMNVLLQAGVDINAQDADGWTSLH 281

Query: 620 IAAKKNQMDIATSLLEYGADANAVTRQGIASVHLAAQE 657
            A    Q D    L+++  D +     G     LA +E
Sbjct: 282 AAVHWGQEDSCQVLVDHFCDMDVKNNAGHTVFDLADKE 395

 Score = 38.1 bits (87), Expect = 0.032,   Method: Compositional matrix adjust.
 Identities = 23/72 (31%), Positives = 35/72 (48%)
 Frame = +3

Query: 352 TALHVAAHCGHYKVAKVLLDKKASPNAKALNGFTPLHIACKKNRIRVMELLLKHGASIQA 411
           TALHV+A  G+  V  VLL      NA+  +G+T LH A    +    ++L+ H   +  
Sbjct: 171 TALHVSAAKGYINVMNVLLQAGVDINAQDADGWTSLHAAVHWGQEDSCQVLVDHFCDMDV 350

Query: 412 VTESGLTPIHVA 423
              +G T   +A
Sbjct: 351 KNNAGHTVFDLA 386

 Score = 36.2 bits (82), Expect = 0.11,   Method: Compositional matrix adjust.
 Identities = 25/95 (26%), Positives = 44/95 (46%)
 Frame = +3

Query: 176 LENDTKGKVRLPALHIAARKDDTKAAALLLQNDTNADVESKSGFTPLHIAAHYGNINVAT 235
           +E++   K    ALH++A K       +LLQ   + + +   G+T LH A H+G  +   
Sbjct: 138 IEDNAHPKTGATALHVSAAKGYINVMNVLLQAGVDINAQDADGWTSLHAAVHWGQEDSCQ 317

Query: 236 LLLNRAAAVDFTARNDITPLHVASKRGNANMVKLL 270
           +L++    +D       T   +A K     M+K+L
Sbjct: 318 VLVDHFCDMDVKNNAGHTVFDLADKE----MLKVL 410

 Score = 32.0 bits (71), Expect = 2.1,   Method: Compositional matrix adjust.
 Identities = 30/113 (26%), Positives = 50/113 (44%), Gaps = 7/113 (6%)
 Frame = +3

Query: 4   EPKEKPAKPAHRKRKGKKSDANASYLRAARAGHLEKALDYI-------KNGVDVNICNQN 56
           E ++   + A+R  + K  + NA     A A H+  A  YI       + GVD+N  + +
Sbjct: 84  EEEDMMMEDANRWLQNKNIEDNAHPKTGATALHVSAAKGYINVMNVLLQAGVDINAQDAD 263

Query: 57  GLNALHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQAEVVKVL 109
           G  +LH A   G  +    L+    ++D     G+T   +A      E++KVL
Sbjct: 264 GWTSLHAAVHWGQEDSCQVLVDHFCDMDVKNNAGHTVFDLAD----KEMLKVL 410
>20036
          Length = 1849

 Score = 60.1 bits (144), Expect = 7e-09,   Method: Compositional matrix adjust.
 Identities = 53/166 (31%), Positives = 76/166 (45%), Gaps = 7/166 (4%)
 Frame = +3

Query: 628 DIATSLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLSRN-ANVNLSNKSGLTPLHL 686
           +I+  LLEY    N V   G +++H      + D+V LLL     +V   NK+G TP  L
Sbjct: 834 EISHRLLEYIV--NLVDSNGNSAIHYCVSHCNFDIVGLLLDTEVCDVKRPNKAGYTPTML 1007

Query: 687 AA-----QEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNA 741
           A+      +D  ++   L   G       + G T L +        +V  LL+  A  N 
Sbjct: 1008ASLAFIQNDDHRDIIRQLFLAGDINACAEQTGQTALMLATSQCRTDMVELLLETGADCNQ 1187

Query: 742 KTKNGYTALHQAAQQGHTHIINVLLQNNASPNELTVNGN-TALAIA 786
           +  +G TAL  A + GHT I+ +LL        LT N N TAL+IA
Sbjct: 1188QDFDGSTALMCACEHGHTAIVQLLLAQPHCDATLTDNENSTALSIA 1325

 Score = 57.0 bits (136), Expect = 7e-08,   Method: Compositional matrix adjust.
 Identities = 46/145 (31%), Positives = 72/145 (49%), Gaps = 7/145 (4%)
 Frame = +3

Query: 39  KALDYIKNGVDVNICNQNGLNALHLASKEGHVEVVSELLQRE-ANVDAATKKGNTALHIA 97
           + L+YI     VN+ + NG +A+H      + ++V  LL  E  +V    K G T   +A
Sbjct: 846 RLLEYI-----VNLVDSNGNSAIHYCVSHCNFDIVGLLLDTEVCDVKRPNKAGYTPTMLA 1010

Query: 98  SLA-----GQAEVVKVLVTNGANVNAQS-QNGFTPLYMAAQENHLEVVRFLLDNGASQSL 151
           SLA        ++++ L   G ++NA + Q G T L +A  +   ++V  LL+ GA  + 
Sbjct: 1011SLAFIQNDDHRDIIRQLFLAG-DINACAEQTGQTALMLATSQCRTDMVELLLETGADCNQ 1187

Query: 152 ATEDGFTPLAVALQQGHDQVVSLLL 176
              DG T L  A + GH  +V LLL
Sbjct: 1188QDFDGSTALMCACEHGHTAIVQLLL 1262

 Score = 51.2 bits (121), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 39/166 (23%), Positives = 74/166 (44%), Gaps = 7/166 (4%)
 Frame = +3

Query: 541  LSITTKKGFTPLHVAAKYGKLEVASLLLQKSASP-DAAGKSGLTPLHVAA-----HYDNQ 594
            +++    G + +H    +   ++  LLL           K+G TP  +A+     + D++
Sbjct: 864  VNLVDSNGNSAIHYCVSHCNFDIVGLLLDTEVCDVKRPNKAGYTPTMLASLAFIQNDDHR 1043

Query: 595  KVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATSLLEYGADANAVTRQGIASVHLA 654
             +   L   G     A + G T L +A  + + D+   LLE GAD N     G  ++  A
Sbjct: 1044 DIIRQLFLAGDINACAEQTGQTALMLATSQCRTDMVELLLETGADCNQQDFDGSTALMCA 1223

Query: 655  AQEGHVDMVSLLLSR-NANVNLSNKSGLTPLHLAAQEDRVNVAEVL 699
             + GH  +V LLL++ + +  L++    T L +A +    ++  +L
Sbjct: 1224 CEHGHTAIVQLLLAQPHCDATLTDNENSTALSIAMEASHKDIGVIL 1361

 Score = 47.4 bits (111), Expect = 6e-05,   Method: Compositional matrix adjust.
 Identities = 44/161 (27%), Positives = 76/161 (47%), Gaps = 9/161 (5%)
 Frame = +3

Query: 188  ALHIAARKDDTKAAALLLQNDTNADVE--SKSGFTPLHIA--AHYGNINVATLLLNRAAA 243
            A+H      +     LLL  +   DV+  +K+G+TP  +A  A   N +   ++     A
Sbjct: 894  AIHYCVSHCNFDIVGLLLDTEV-CDVKRPNKAGYTPTMLASLAFIQNDDHRDIIRQLFLA 1070

Query: 244  VDFTA---RNDITPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVV 300
             D  A   +   T L +A+ +   +MV+LLL+ GA  + +  DG T L C    GH  +V
Sbjct: 1071 GDINACAEQTGQTALMLATSQCRTDMVELLLETGADCNQQDFDGSTALMCACEHGHTAIV 1250

Query: 301  EMLLDR--SAPILSKTKNGLSPLHMATQGDHLNCVQLLLQH 339
            ++LL +      L+  +N  + L +A +  H +   +L +H
Sbjct: 1251 QLLLAQPHCDATLTDNENS-TALSIAMEASHKDIGVILYKH 1370

 Score = 41.2 bits (95), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 45/166 (27%), Positives = 65/166 (39%), Gaps = 13/166 (7%)
 Frame = +3

Query: 484  TPLHISARLGKADIVQQLLQQGAS----PNAATTSGYTPLHLAA-----REGHEDVAAFL 534
            + +H        DIV  LL         PN A   GYTP  LA+      + H D+   L
Sbjct: 891  SAIHYCVSHCNFDIVGLLLDTEVCDVKRPNKA---GYTPTMLASLAFIQNDDHRDIIRQL 1061

Query: 535  LDHGASLSITTKKGFTPLHVAAKYGKLEVASLLLQKSASPDAAGKSGLTPLHVAAHYDNQ 594
               G   +   + G T L +A    + ++  LLL+  A  +     G T L  A  + + 
Sbjct: 1062 FLAGDINACAEQTGQTALMLATSQCRTDMVELLLETGADCNQQDFDGSTALMCACEHGHT 1241

Query: 595  KVALLLLDQGASPHAAA----KNGYTPLHIAAKKNQMDIATSLLEY 636
             +  LLL   A PH  A        T L IA + +  DI   L ++
Sbjct: 1242 AIVQLLL---AQPHCDATLTDNENSTALSIAMEASHKDIGVILYKH 1370

 Score = 34.3 bits (77), Expect = 0.46,   Method: Compositional matrix adjust.
 Identities = 41/172 (23%), Positives = 66/172 (38%), Gaps = 10/172 (5%)
 Frame = +3

Query: 244  VDFTARNDITPLHVASKRGNANMVKLLLD-RGAKIDAKTRDGLTPLHCGA-----RSGHE 297
            V+    N  + +H      N ++V LLLD     +    + G TP    +        H 
Sbjct: 864  VNLVDSNGNSAIHYCVSHCNFDIVGLLLDTEVCDVKRPNKAGYTPTMLASLAFIQNDDHR 1043

Query: 298  QVVEMLLDRSAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVA 357
             ++  L           + G + L +AT     + V+LLL+     +    D  TAL  A
Sbjct: 1044 DIIRQLFLAGDINACAEQTGQTALMLATSQCRTDMVELLLETGADCNQQDFDGSTALMCA 1223

Query: 358  AHCGHYKVAKVLLDKKASPNAKAL----NGFTPLHIACKKNRIRVMELLLKH 405
               GH  + ++LL   A P+  A        T L IA + +   +  +L KH
Sbjct: 1224 CEHGHTAIVQLLL---AQPHCDATLTDNENSTALSIAMEASHKDIGVILYKH 1370

 Score = 33.5 bits (75), Expect = 0.69,   Method: Compositional matrix adjust.
 Identities = 41/158 (25%), Positives = 61/158 (38%), Gaps = 9/158 (5%)
 Frame = +3

Query: 316  NGLSPLHMATQGDHLNCVQLLLQHNVPVDDV--------TNDYLTALHVAAHCGHYKVAK 367
            NG S +H      + + V LLL  +  V DV        T   L +L    +  H  + +
Sbjct: 882  NGNSAIHYCVSHCNFDIVGLLL--DTEVCDVKRPNKAGYTPTMLASLAFIQNDDHRDIIR 1055

Query: 368  VLLDKKASPNAKALNGFTPLHIACKKNRIRVMELLLKHGASIQAVTESGLTPIHVAAFMG 427
             L             G T L +A  + R  ++ELLL+ GA        G T +  A   G
Sbjct: 1056 QLFLAGDINACAEQTGQTALMLATSQCRTDMVELLLETGADCNQQDFDGSTALMCACEHG 1235

Query: 428  HVNIVSQLMHHGASPNT-TNVRGETALHMAARSGQAEV 464
            H  IV  L+       T T+    TAL +A  +   ++
Sbjct: 1236 HTAIVQLLLAQPHCDATLTDNENSTALSIAMEASHKDI 1349
>21532
          Length = 460

 Score = 59.7 bits (143), Expect = 9e-09,   Method: Compositional matrix adjust.
 Identities = 37/113 (32%), Positives = 53/113 (46%), Gaps = 7/113 (6%)
 Frame = -1

Query: 464 VVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASP-------NAATTSGY 516
           ++  L+  GA V  +     TP   +  LG    V+ LL  G SP       N    S  
Sbjct: 451 IINTLLSHGADVNIRDNTGCTPFANACCLGNLAAVKALLTPGESPSWSKPMINVRDNSQN 272

Query: 517 TPLHLAAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVASLLLQ 569
           TPLHLA++EGH  +   L++H A L+     G  PL +A +Y    V ++L Q
Sbjct: 271 TPLHLASQEGHTAIVELLVEHKADLAAKNDSGHNPLSLARQYKHENVVAVLQQ 113

 Score = 55.8 bits (133), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 38/115 (33%), Positives = 58/115 (50%), Gaps = 9/115 (7%)
 Frame = -1

Query: 70  VEVVSELLQREANVDAATKKGNTALHIASLAGQAEVVKVLVTNGA---------NVNAQS 120
           V +++ LL   A+V+     G T    A   G    VK L+T G          NV   S
Sbjct: 457 VPIINTLLSHGADVNIRDNTGCTPFANACCLGNLAAVKALLTPGESPSWSKPMINVRDNS 278

Query: 121 QNGFTPLYMAAQENHLEVVRFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLL 175
           QN  TPL++A+QE H  +V  L+++ A  +   + G  PL++A Q  H+ VV++L
Sbjct: 277 QN--TPLHLASQEGHTAIVELLVEHKADLAAKNDSGHNPLSLARQYKHENVVAVL 119

 Score = 55.5 bits (132), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 37/116 (31%), Positives = 55/116 (47%), Gaps = 7/116 (6%)
 Frame = -1

Query: 230 NINVATLLLNRAAAVDFTARNDITPLHVASKRGNANMVKLLLDRGAK-------IDAKTR 282
           N+ +   LL+  A V+       TP   A   GN   VK LL  G         I+ +  
Sbjct: 460 NVPIINTLLSHGADVNIRDNTGCTPFANACCLGNLAAVKALLTPGESPSWSKPMINVRDN 281

Query: 283 DGLTPLHCGARSGHEQVVEMLLDRSAPILSKTKNGLSPLHMATQGDHLNCVQLLLQ 338
              TPLH  ++ GH  +VE+L++  A + +K  +G +PL +A Q  H N V +L Q
Sbjct: 280 SQNTPLHLASQEGHTAIVELLVEHKADLAAKNDSGHNPLSLARQYKHENVVAVLQQ 113

 Score = 48.5 bits (114), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 35/113 (30%), Positives = 53/113 (46%), Gaps = 7/113 (6%)
 Frame = -1

Query: 629 IATSLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLSRNAN-------VNLSNKSGL 681
           I  +LL +GAD N     G      A   G++  V  LL+   +       +N+ + S  
Sbjct: 451 IINTLLSHGADVNIRDNTGCTPFANACCLGNLAAVKALLTPGESPSWSKPMINVRDNSQN 272

Query: 682 TPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQ 734
           TPLHLA+QE    + E+LV   A + A+   G+ PL +   Y +  +V  L Q
Sbjct: 271 TPLHLASQEGHTAIVELLVEHKADLAAKNDSGHNPLSLARQYKHENVVAVLQQ 113

 Score = 45.1 bits (105), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 33/111 (29%), Positives = 49/111 (44%), Gaps = 7/111 (6%)
 Frame = -1

Query: 497 IVQQLLQQGASPNAATTSGYTPLHLAAREGHEDVAAFLLDHGAS-------LSITTKKGF 549
           I+  LL  GA  N    +G TP   A   G+      LL  G S       +++      
Sbjct: 451 IINTLLSHGADVNIRDNTGCTPFANACCLGNLAAVKALLTPGESPSWSKPMINVRDNSQN 272

Query: 550 TPLHVAAKYGKLEVASLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLL 600
           TPLH+A++ G   +  LL++  A   A   SG  PL +A  Y ++ V  +L
Sbjct: 271 TPLHLASQEGHTAIVELLVEHKADLAAKNDSGHNPLSLARQYKHENVVAVL 119

 Score = 45.1 bits (105), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 33/110 (30%), Positives = 51/110 (46%), Gaps = 7/110 (6%)
 Frame = -1

Query: 333 VQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKASP-------NAKALNGFT 385
           +  LL H   V+   N   T    A   G+    K LL    SP       N +  +  T
Sbjct: 448 INTLLSHGADVNIRDNTGCTPFANACCLGNLAAVKALLTPGESPSWSKPMINVRDNSQNT 269

Query: 386 PLHIACKKNRIRVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQL 435
           PLH+A ++    ++ELL++H A + A  +SG  P+ +A    H N+V+ L
Sbjct: 268 PLHLASQEGHTAIVELLVEHKADLAAKNDSGHNPLSLARQYKHENVVAVL 119

 Score = 42.7 bits (99), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 31/107 (28%), Positives = 46/107 (42%), Gaps = 7/107 (6%)
 Frame = -1

Query: 534 LLDHGASLSITTKKGFTPLHVAAKYGKLEVASLLLQKSASP-------DAAGKSGLTPLH 586
           LL HGA ++I    G TP   A   G L     LL    SP       +    S  TPLH
Sbjct: 439 LLSHGADVNIRDNTGCTPFANACCLGNLAAVKALLTPGESPSWSKPMINVRDNSQNTPLH 260

Query: 587 VAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATSL 633
           +A+   +  +  LL++  A   A   +G+ PL +A +    ++   L
Sbjct: 259 LASQEGHTAIVELLVEHKADLAAKNDSGHNPLSLARQYKHENVVAVL 119

 Score = 42.4 bits (98), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 35/107 (32%), Positives = 44/107 (41%), Gaps = 7/107 (6%)
 Frame = -1

Query: 600 LLDQGASPHAAAKNGYTPLHIAAKKNQMDIATSLLEYGADA-------NAVTRQGIASVH 652
           LL  GA  +     G TP   A     +    +LL  G          N         +H
Sbjct: 439 LLSHGADVNIRDNTGCTPFANACCLGNLAAVKALLTPGESPSWSKPMINVRDNSQNTPLH 260

Query: 653 LAAQEGHVDMVSLLLSRNANVNLSNKSGLTPLHLAAQEDRVNVAEVL 699
           LA+QEGH  +V LL+   A++   N SG  PL LA Q    NV  VL
Sbjct: 259 LASQEGHTAIVELLVEHKADLAAKNDSGHNPLSLARQYKHENVVAVL 119

 Score = 39.3 bits (90), Expect = 0.013,   Method: Compositional matrix adjust.
 Identities = 34/113 (30%), Positives = 45/113 (39%), Gaps = 7/113 (6%)
 Frame = -1

Query: 365 VAKVLLDKKASPNAKALNGFTPLHIACKKNRIRVMELLLKHGAS-------IQAVTESGL 417
           +   LL   A  N +   G TP   AC    +  ++ LL  G S       I     S  
Sbjct: 451 IINTLLSHGADVNIRDNTGCTPFANACCLGNLAAVKALLTPGESPSWSKPMINVRDNSQN 272

Query: 418 TPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQ 470
           TP+H+A+  GH  IV  L+ H A     N  G   L +A +     VV  L Q
Sbjct: 271 TPLHLASQEGHTAIVELLVEHKADLAAKNDSGHNPLSLARQYKHENVVAVLQQ 113

 Score = 35.4 bits (80), Expect = 0.22,   Method: Compositional matrix adjust.
 Identities = 19/49 (38%), Positives = 28/49 (57%)
 Frame = -1

Query: 61  LHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQAEVVKVL 109
           LHLAS+EGH  +V  L++ +A++ A    G+  L +A       VV VL
Sbjct: 265 LHLASQEGHTAIVELLVEHKADLAAKNDSGHNPLSLARQYKHENVVAVL 119

 Score = 34.7 bits (78), Expect = 0.34,   Method: Compositional matrix adjust.
 Identities = 35/135 (25%), Positives = 54/135 (40%), Gaps = 2/135 (1%)
 Frame = -1

Query: 138 VVRFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLLENDTKGKVRLPALHIAARKDD 197
           ++  LL +GA  ++    G TP A A   G+   V  LL          P +        
Sbjct: 451 IINTLLSHGADVNIRDNTGCTPFANACCLGNLAAVKALLTPGESPSWSKPMI-------- 296

Query: 198 TKAAALLLQNDTNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDI--TPL 255
                         +V   S  TPLH+A+  G+  +  LL+   A  D  A+ND    PL
Sbjct: 295 --------------NVRDNSQNTPLHLASQEGHTAIVELLVEHKA--DLAAKNDSGHNPL 164

Query: 256 HVASKRGNANMVKLL 270
            +A +  + N+V +L
Sbjct: 163 SLARQYKHENVVAVL 119
>35952
          Length = 1624

 Score = 43.5 bits (101), Expect(2) = 2e-08,   Method: Compositional matrix adjust.
 Identities = 30/76 (39%), Positives = 43/76 (56%), Gaps = 2/76 (2%)
 Frame = -1

Query: 671  ANVNLSN-KSGLTPLHLAAQEDRVNVAEVLVNQG-AHVDAQTKMGYTPLHVGCHYGNIKI 728
            ANV+L + KSG T LH A + D + VA  L+ +  A V+A+   G TPLHV C  G I +
Sbjct: 1003 ANVDLPDGKSGRTALHHAVELDDLPVAGFLLMEANADVNARCFDGNTPLHVACCRGLIGM 824

Query: 729  VNFLLQHSAKVNAKTK 744
            V  L+   A  + + +
Sbjct: 823  VALLMTAGALTDVENE 776

 Score = 35.0 bits (79), Expect(2) = 2e-08,   Method: Composition-based stats.
 Identities = 24/82 (29%), Positives = 36/82 (43%), Gaps = 18/82 (21%)
 Frame = -2

Query: 604  GASPHAAAKNGYTPLHIAAKKNQMDIATSLLEYGADANAVTRQGIAS------------- 650
            G  P  A +NG TP H+A   + ++   SL++Y        R G+ +             
Sbjct: 1239 GRDPSLADRNGNTPAHLAVLNSSLEALQSLVKY-------LRPGVTAANPFPELDYLNYE 1081

Query: 651  -----VHLAAQEGHVDMVSLLL 667
                 VHLA Q G VDM+ +L+
Sbjct: 1080 *DYTPVHLATQCGSVDMLRMLV 1015

 Score = 39.7 bits (91), Expect(2) = 2e-04,   Method: Compositional matrix adjust.
 Identities = 39/125 (31%), Positives = 51/125 (40%), Gaps = 2/125 (1%)
 Frame = -1

Query: 182 GKVRLPALHIAARKDDTKAAALLLQNDTNADVESK--SGFTPLHIAAHYGNINVATLLLN 239
           GK    ALH A   DD   A  LL  + NADV ++   G TPLH+A   G I +  LL+ 
Sbjct: 982 GKSGRTALHHAVELDDLPVAGFLLM-EANADVNARCFDGNTPLHVACCRGLIGMVALLMT 806

Query: 240 RAAAVDFTARNDITPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQV 299
             A  D    N+  P     + G           G     K R GL P    A     ++
Sbjct: 805 AGALTDV--ENEEIPPEDKEEAG-----------GETGSRKCRRGLLPRDYAAGKDRLRI 665

Query: 300 VEMLL 304
           + ML+
Sbjct: 664 LRMLM 650

 Score = 24.6 bits (52), Expect(2) = 2e-04,   Method: Composition-based stats.
 Identities = 18/69 (26%), Positives = 33/69 (47%), Gaps = 11/69 (15%)
 Frame = -2

Query: 86   ATKKGNTALHIASLAGQAEVVKVLV------TNGANVNAQ-----SQNGFTPLYMAAQEN 134
            A + GNT  H+A L    E ++ LV         AN   +      +  +TP+++A Q  
Sbjct: 1221 ADRNGNTPAHLAVLNSSLEALQSLVKYLRPGVTAANPFPELDYLNYE*DYTPVHLATQCG 1042

Query: 135  HLEVVRFLL 143
             ++++R L+
Sbjct: 1041 SVDMLRMLV 1015

 Score = 45.4 bits (106), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 46/143 (32%), Positives = 63/143 (44%), Gaps = 3/143 (2%)
 Frame = -1

Query: 210  NADV-ESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFTAR--NDITPLHVASKRGNANM 266
            N D+ + KSG T LH A    ++ VA  LL  A A D  AR  +  TPLHVA  RG   M
Sbjct: 1000 NVDLPDGKSGRTALHHAVELDDLPVAGFLLMEANA-DVNARCFDGNTPLHVACCRGLIGM 824

Query: 267  VKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRSAPILSKTKNGLSPLHMATQ 326
            V LL+  GA  D +  +   P      +G E               K + GL P   A  
Sbjct: 823  VALLMTAGALTDVENEE--IPPEDKEEAGGETGSR-----------KCRRGLLPRDYAAG 683

Query: 327  GDHLNCVQLLLQHNVPVDDVTND 349
             D L  +++L+      +D+ +D
Sbjct: 682  KDRLRILRMLMGDLATEEDLNSD 614

 Score = 38.9 bits (89), Expect(2) = 2e-04,   Method: Compositional matrix adjust.
 Identities = 26/66 (39%), Positives = 36/66 (54%), Gaps = 1/66 (1%)
 Frame = -1

Query: 574 PDAAGKSGLTPLHVAAHYDNQKVA-LLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATS 632
           PD  GKSG T LH A   D+  VA  LL++  A  +A   +G TPLH+A  +  + +   
Sbjct: 988 PD--GKSGRTALHHAVELDDLPVAGFLLMEANADVNARCFDGNTPLHVACCRGLIGMVAL 815

Query: 633 LLEYGA 638
           L+  GA
Sbjct: 814 LMTAGA 797

 Score = 25.4 bits (54), Expect(2) = 2e-04,   Method: Composition-based stats.
 Identities = 18/79 (22%), Positives = 37/79 (46%), Gaps = 11/79 (13%)
 Frame = -2

Query: 505  GASPNAATTSGYTPLHLAAREGHEDVAAFLLDH---GASLS--------ITTKKGFTPLH 553
            G  P+ A  +G TP HLA      +    L+ +   G + +        +  +  +TP+H
Sbjct: 1239 GRDPSLADRNGNTPAHLAVLNSSLEALQSLVKYLRPGVTAANPFPELDYLNYE*DYTPVH 1060

Query: 554  VAAKYGKLEVASLLLQKSA 572
            +A + G +++  +L++ S 
Sbjct: 1059 LATQCGSVDMLRMLVRGSG 1003

 Score = 42.0 bits (97), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 24/57 (42%), Positives = 32/57 (56%), Gaps = 1/57 (1%)
 Frame = -1

Query: 352 TALHVAAHCGHYKVAKVLL-DKKASPNAKALNGFTPLHIACKKNRIRVMELLLKHGA 407
           TALH A       VA  LL +  A  NA+  +G TPLH+AC +  I ++ LL+  GA
Sbjct: 967 TALHHAVELDDLPVAGFLLMEANADVNARCFDGNTPLHVACCRGLIGMVALLMTAGA 797

 Score = 40.8 bits (94), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 35/131 (26%), Positives = 60/131 (45%), Gaps = 24/131 (18%)
 Frame = -1

Query: 43   YIKNGVDVNIC---NQNGLNALHLASKEGHVEVVSELL-QREANVDAATKKGNTALHIAS 98
            Y+  GV  N+     ++G  ALH A +   + V   LL +  A+V+A    GNT LH+A 
Sbjct: 1024 YVGAGVRANVDLPDGKSGRTALHHAVELDDLPVAGFLLMEANADVNARCFDGNTPLHVAC 845

Query: 99   LAGQAEVVKVLVTNGANVNAQSQN--------------------GFTPLYMAAQENHLEV 138
              G   +V +L+T GA  + +++                     G  P   AA ++ L +
Sbjct: 844  CRGLIGMVALLMTAGALTDVENEEIPPEDKEEAGGETGSRKCRRGLLPRDYAAGKDRLRI 665

Query: 139  VRFLLDNGASQ 149
            +R L+ + A++
Sbjct: 664  LRMLMGDLATE 632

 Score = 36.2 bits (82), Expect = 0.12,   Method: Compositional matrix adjust.
 Identities = 31/92 (33%), Positives = 46/92 (50%), Gaps = 4/92 (4%)
 Frame = -1

Query: 359  HCGHYKVAKVLLDKKAS---PNAKALNGFTPLHIACKKNRIRVME-LLLKHGASIQAVTE 414
             CGH   A V    +A+   P+ K+  G T LH A + + + V   LL++  A + A   
Sbjct: 1042 QCGH--AAYVGAGVRANVDLPDGKS--GRTALHHAVELDDLPVAGFLLMEANADVNARCF 875

Query: 415  SGLTPIHVAAFMGHVNIVSQLMHHGASPNTTN 446
             G TP+HVA   G + +V+ LM  GA  +  N
Sbjct: 874  DGNTPLHVACCRGLIGMVALLMTAGALTDVEN 779

 Score = 32.0 bits (71), Expect = 2.1,   Method: Compositional matrix adjust.
 Identities = 24/63 (38%), Positives = 31/63 (49%), Gaps = 1/63 (1%)
 Frame = -1

Query: 514 SGYTPLHLAAREGHEDVAAFLL-DHGASLSITTKKGFTPLHVAAKYGKLEVASLLLQKSA 572
           SG T LH A       VA FLL +  A ++     G TPLHVA   G + + +LL+   A
Sbjct: 976 SGRTALHHAVELDDLPVAGFLLMEANADVNARCFDGNTPLHVACCRGLIGMVALLMTAGA 797

Query: 573 SPD 575
             D
Sbjct: 796 LTD 788

 Score = 31.2 bits (69), Expect = 3.7,   Method: Compositional matrix adjust.
 Identities = 16/47 (34%), Positives = 25/47 (53%)
 Frame = -1

Query: 665 LLLSRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTK 711
           LL+  NA+VN     G TPLH+A     + +  +L+  GA  D + +
Sbjct: 916 LLMEANADVNARCFDGNTPLHVACCRGLIGMVALLMTAGALTDVENE 776

 Score = 30.4 bits (67), Expect = 6.9,   Method: Compositional matrix adjust.
 Identities = 24/61 (39%), Positives = 31/61 (50%), Gaps = 1/61 (1%)
 Frame = -1

Query: 546 KKGFTPLHVAAKYGKLEVAS-LLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQG 604
           K G T LH A +   L VA  LL++ +A  +A    G TPLHVA       +  LL+  G
Sbjct: 979 KSGRTALHHAVELDDLPVAGFLLMEANADVNARCFDGNTPLHVACCRGLIGMVALLMTAG 800

Query: 605 A 605
           A
Sbjct: 799 A 797

 Score = 30.0 bits (66), Expect = 7.5,   Method: Compositional matrix adjust.
 Identities = 28/100 (28%), Positives = 45/100 (45%), Gaps = 7/100 (7%)
 Frame = -1

Query: 365  VAKVLLDKKASPNAKALNGFTPLHIACKKNRIRVMELLLKHGASIQAVTESGLTPIHVAA 424
            V K ++ K      +AL  F+    A      R + L+ +H  +I+   E+G  PIH+A 
Sbjct: 1555 VVKRIMKKVTEKTVRALRDFSETGDA------RYLLLVQRHLTAIK--NENGDLPIHLAV 1400

Query: 425  FMGHVNIVSQLMHHGAS-------PNTTNVRGETALHMAA 457
                 + +  L++   S        NT N   +TALH+AA
Sbjct: 1399 INNQTSSLQHLLYVMTSLPNARHVVNTFNYVRQTALHLAA 1280
>12417
          Length = 954

 Score = 58.5 bits (140), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 30/77 (38%), Positives = 48/77 (62%)
 Frame = +2

Query: 717 LHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTALHQAAQQGHTHIINVLLQNNASPNELT 776
           L +  + G  K+ + L+Q  A VN+ T++G T LH A+ QGH HI+++LL+  A  +   
Sbjct: 245 LAMAANRGLDKMCSQLIQTGADVNSATEHGRTPLHXASAQGHGHIVDLLLEKGADIDAED 424

Query: 777 VNGNTALAIARRLGYIS 793
             G+TAL+IA + G+ S
Sbjct: 425 DYGDTALSIADQFGFKS 475

 Score = 54.3 bits (129), Expect = 4e-07,   Method: Compositional matrix adjust.
 Identities = 40/130 (30%), Positives = 61/130 (46%)
 Frame = +2

Query: 430 NIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHIS 489
           N V  +M  G + N T  R   + +M  R+ +A            +E +A      L ++
Sbjct: 122 NDVDHVMMLGVT-NPTEYRSPNSDYMTKRARKA-----------WLEERA---SVALAMA 256

Query: 490 ARLGKADIVQQLLQQGASPNAATTSGYTPLHLAAREGHEDVAAFLLDHGASLSITTKKGF 549
           A  G   +  QL+Q GA  N+AT  G TPLH A+ +GH  +   LL+ GA +      G 
Sbjct: 257 ANRGLDKMCSQLIQTGADVNSATEHGRTPLHXASAQGHGHIVDLLLEKGADIDAEDDYGD 436

Query: 550 TPLHVAAKYG 559
           T L +A ++G
Sbjct: 437 TALSIADQFG 466

 Score = 50.8 bits (120), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 25/58 (43%), Positives = 35/58 (60%)
 Frame = +2

Query: 44  IKNGVDVNICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAG 101
           I+ G DVN   ++G   LH AS +GH  +V  LL++ A++DA    G+TAL IA   G
Sbjct: 293 IQTGADVNSATEHGRTPLHXASAQGHGHIVDLLLEKGADIDAEDDYGDTALSIADQFG 466

 Score = 49.3 bits (116), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 27/83 (32%), Positives = 45/83 (54%)
 Frame = +2

Query: 255 LHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRSAPILSKT 314
           L +A+ RG   M   L+  GA +++ T  G TPLH  +  GH  +V++LL++ A I ++ 
Sbjct: 245 LAMAANRGLDKMCSQLIQTGADVNSATEHGRTPLHXASAQGHGHIVDLLLEKGADIDAED 424

Query: 315 KNGLSPLHMATQGDHLNCVQLLL 337
             G + L +A Q    +C + L 
Sbjct: 425 DYGDTALSIADQFGFKSCGRXLF 493

 Score = 48.9 bits (115), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 34/115 (29%), Positives = 55/115 (47%)
 Frame = +2

Query: 364 KVAKVLLDKKASPNAKALNGFTPLHIACKKNRIRVMELLLKHGASIQAVTESGLTPIHVA 423
           +  K  L+++AS           L +A  +   ++   L++ GA + + TE G TP+H A
Sbjct: 203 RARKAWLEERAS---------VALAMAANRGLDKMCSQLIQTGADVNSATEHGRTPLHXA 355

Query: 424 AFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAK 478
           +  GH +IV  L+  GA  +  +  G+TAL +A + G     R L     Q  AK
Sbjct: 356 SAQGHGHIVDLLLEKGADIDAEDDYGDTALSIADQFGFKSCGRXLFLFHWQQRAK 520

 Score = 48.5 bits (114), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 31/104 (29%), Positives = 50/104 (48%), Gaps = 4/104 (3%)
 Frame = +2

Query: 653 LAAQEGHVDMVSLLLSRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKM 712
           +AA  G   M S L+   A+VN + + G TPLH A+ +   ++ ++L+ +GA +DA+   
Sbjct: 251 MAANRGLDKMCSQLIQTGADVNSATEHGRTPLHXASAQGHGHIVDLLLEKGADIDAEDDY 430

Query: 713 GYTPLHVGCHYG----NIKIVNFLLQHSAKVNAKTKNGYTALHQ 752
           G T L +   +G       +  F  Q  AK     +N     HQ
Sbjct: 431 GDTALSIADQFGFKSCGRXLFLFHWQQRAKKVTPARNIPLKPHQ 562

 Score = 48.1 bits (113), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 24/72 (33%), Positives = 41/72 (56%)
 Frame = +2

Query: 618 LHIAAKKNQMDIATSLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLSRNANVNLSN 677
           L +AA +    + + L++ GAD N+ T  G   +H A+ +GH  +V LLL + A+++  +
Sbjct: 245 LAMAANRGLDKMCSQLIQTGADVNSATEHGRTPLHXASAQGHGHIVDLLLEKGADIDAED 424

Query: 678 KSGLTPLHLAAQ 689
             G T L +A Q
Sbjct: 425 DYGDTALSIADQ 460

 Score = 47.8 bits (112), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 30/88 (34%), Positives = 44/88 (50%)
 Frame = +2

Query: 448 RGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGAS 507
           R   AL MAA  G  ++   L+Q GA V +  +  +TPLH ++  G   IV  LL++GA 
Sbjct: 230 RASVALAMAANRGLDKMCSQLIQTGADVNSATEHGRTPLHXASAQGHGHIVDLLLEKGAD 409

Query: 508 PNAATTSGYTPLHLAAREGHEDVAAFLL 535
            +A    G T L +A + G +     L 
Sbjct: 410 IDAEDDYGDTALSIADQFGFKSCGRXLF 493

 Score = 45.1 bits (105), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 26/73 (35%), Positives = 39/73 (53%)
 Frame = +2

Query: 519 LHLAAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVASLLLQKSASPDAAG 578
           L +AA  G + + + L+  GA ++  T+ G TPLH A+  G   +  LLL+K A  DA  
Sbjct: 245 LAMAANRGLDKMCSQLIQTGADVNSATEHGRTPLHXASAQGHGHIVDLLLEKGADIDAED 424

Query: 579 KSGLTPLHVAAHY 591
             G T L +A  +
Sbjct: 425 DYGDTALSIADQF 463

 Score = 44.7 bits (104), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 27/74 (36%), Positives = 39/74 (52%)
 Frame = +2

Query: 684 LHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKT 743
           L +AA      +   L+  GA V++ T+ G TPLH     G+  IV+ LL+  A ++A+ 
Sbjct: 245 LAMAANRGLDKMCSQLIQTGADVNSATEHGRTPLHXASAQGHGHIVDLLLEKGADIDAED 424

Query: 744 KNGYTALHQAAQQG 757
             G TAL  A Q G
Sbjct: 425 DYGDTALSIADQFG 466

 Score = 44.7 bits (104), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 27/74 (36%), Positives = 42/74 (56%)
 Frame = +2

Query: 222 LHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRGNANMVKLLLDRGAKIDAKT 281
           L +AA+ G   + + L+   A V+    +  TPLH AS +G+ ++V LLL++GA IDA+ 
Sbjct: 245 LAMAANRGLDKMCSQLIQTGADVNSATEHGRTPLHXASAQGHGHIVDLLLEKGADIDAED 424

Query: 282 RDGLTPLHCGARSG 295
             G T L    + G
Sbjct: 425 DYGDTALSIADQFG 466

 Score = 42.4 bits (98), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 24/72 (33%), Positives = 37/72 (51%)
 Frame = +2

Query: 422 VAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKD 481
           +AA  G   + SQL+  GA  N+    G T LH A+  G   +V  L++ GA ++A+   
Sbjct: 251 MAANRGLDKMCSQLIQTGADVNSATEHGRTPLHXASAQGHGHIVDLLLEKGADIDAEDDY 430

Query: 482 DQTPLHISARLG 493
             T L I+ + G
Sbjct: 431 GDTALSIADQFG 466

 Score = 41.6 bits (96), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 26/75 (34%), Positives = 40/75 (53%)
 Frame = +2

Query: 353 ALHVAAHCGHYKVAKVLLDKKASPNAKALNGFTPLHIACKKNRIRVMELLLKHGASIQAV 412
           AL +AA+ G  K+   L+   A  N+   +G TPLH A  +    +++LLL+ GA I A 
Sbjct: 242 ALAMAANRGLDKMCSQLIQTGADVNSATEHGRTPLHXASAQGHGHIVDLLLEKGADIDAE 421

Query: 413 TESGLTPIHVAAFMG 427
            + G T + +A   G
Sbjct: 422 DDYGDTALSIADQFG 466

 Score = 40.0 bits (92), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 26/74 (35%), Positives = 40/74 (54%)
 Frame = +2

Query: 585 LHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATSLLEYGADANAVT 644
           L +AA+    K+   L+  GA  ++A ++G TPLH A+ +    I   LLE GAD +A  
Sbjct: 245 LAMAANRGLDKMCSQLIQTGADVNSATEHGRTPLHXASAQGHGHIVDLLLEKGADIDAED 424

Query: 645 RQGIASVHLAAQEG 658
             G  ++ +A Q G
Sbjct: 425 DYGDTALSIADQFG 466

 Score = 38.1 bits (87), Expect = 0.028,   Method: Compositional matrix adjust.
 Identities = 26/70 (37%), Positives = 38/70 (54%)
 Frame = +2

Query: 552 LHVAAKYGKLEVASLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAA 611
           L +AA  G  ++ S L+Q  A  ++A + G TPLH A+   +  +  LLL++GA   A  
Sbjct: 245 LAMAANRGLDKMCSQLIQTGADVNSATEHGRTPLHXASAQGHGHIVDLLLEKGADIDAED 424

Query: 612 KNGYTPLHIA 621
             G T L IA
Sbjct: 425 DYGDTALSIA 454

 Score = 38.1 bits (87), Expect = 0.028,   Method: Compositional matrix adjust.
 Identities = 26/84 (30%), Positives = 41/84 (48%), Gaps = 1/84 (1%)
 Frame = +2

Query: 288 LHCGARSGHEQVVEMLLDRSAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVT 347
           L   A  G +++   L+   A + S T++G +PLH A+   H + V LLL+    + D  
Sbjct: 245 LAMAANRGLDKMCSQLIQTGADVNSATEHGRTPLHXASAQGHGHIVDLLLEKGADI-DAE 421

Query: 348 NDY-LTALHVAAHCGHYKVAKVLL 370
           +DY  TAL +A   G     + L 
Sbjct: 422 DDYGDTALSIADQFGFKSCGRXLF 493

 Score = 38.1 bits (87), Expect = 0.029,   Method: Compositional matrix adjust.
 Identities = 23/51 (45%), Positives = 28/51 (54%)
 Frame = +2

Query: 127 LYMAAQENHLEVVRFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLLE 177
           L MAA     ++   L+  GA  + ATE G TPL  A  QGH  +V LLLE
Sbjct: 245 LAMAANRGLDKMCSQLIQTGADVNSATEHGRTPLHXASAQGHGHIVDLLLE 397

 Score = 37.4 bits (85), Expect = 0.047,   Method: Compositional matrix adjust.
 Identities = 23/75 (30%), Positives = 39/75 (52%)
 Frame = +2

Query: 188 ALHIAARKDDTKAAALLLQNDTNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFT 247
           AL +AA +   K  + L+Q   + +  ++ G TPLH A+  G+ ++  LLL + A +D  
Sbjct: 242 ALAMAANRGLDKMCSQLIQTGADVNSATEHGRTPLHXASAQGHGHIVDLLLEKGADIDAE 421

Query: 248 ARNDITPLHVASKRG 262
                T L +A + G
Sbjct: 422 DDYGDTALSIADQFG 466
>16561
          Length = 2029

 Score = 57.4 bits (137), Expect = 5e-08,   Method: Compositional matrix adjust.
 Identities = 74/309 (23%), Positives = 128/309 (41%), Gaps = 41/309 (13%)
 Frame = -3

Query: 315  KNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKA 374
            ++G + LH +  G+  + +QLLL     ++ + N   + LHVA +  H K   VLL+   
Sbjct: 2018 RDGDTALHYSAFGNQPDVLQLLLSKGAKINALNNGGCSTLHVAVNKQHIKCVHVLLNXGC 1839

Query: 375  SPNAKALNGFTPLHIACKKNRIRVMELLLKHGASIQAVTESGLTPIHVA-AFMGHVNIVS 433
              N +   G T LH A  K  ++ +  L        ++T + ++P   + A M  +    
Sbjct: 1838 DVNXQDAYGDTALHDAIGKRAVKSLTSL--------SITLALISPSETSVASMSSIMQP* 1683

Query: 434  QLMHHGASPNTTNV-------RGETALH------MAARSGQAEVVRYLVQDGAQVEAKAK 480
            + M    S + TNV       +    LH      M  R  Q    ++L+++ A+V+ +  
Sbjct: 1682 RAMCLPRSASCTNVDRLWT*GKMMGFLHFTWLL*MDTRMLQ----QHLLRNRAEVDIRNN 1515

Query: 481  DDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLAARE---GHED-------- 529
              QTPL ++   G + +++ L+   A  N +   G T LHLA        ED        
Sbjct: 1514 RQQTPLLLAVSQGHSSLIELLVHAQADINVSDEDGDTCLHLALMRQTVATEDSSRMLDSI 1335

Query: 530  ----------------VAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVASLLLQKSAS 573
                            +A +L   GASL+   ++G  PL V      +E+    LQ+ A+
Sbjct: 1334 RSQLGMGEDEAQTGAAIACYLAQQGASLTACNQQGKXPLDVTTDTRTVEI----LQQFAT 1167

Query: 574  PDAAGKSGL 582
               A  + +
Sbjct: 1166 EFCASNTKI 1140

 Score = 56.6 bits (135), Expect = 8e-08,   Method: Compositional matrix adjust.
 Identities = 80/309 (25%), Positives = 119/309 (38%), Gaps = 47/309 (15%)
 Frame = -3

Query: 480  KDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLAAREGHEDVAAFLLDHGA 539
            +D  T LH SA   + D++Q LL +GA  NA    G + LH+A  + H      LL+ G 
Sbjct: 2018 RDGDTALHYSAFGNQPDVLQLLLSKGAKINALNNGGCSTLHVAVNKQHIKCVHVLLNXGC 1839

Query: 540  SLSITTKKGFTPLHVAAKYGKLEVASL--------LLQKSASPDAAGKSGLTPLHVAAHY 591
             ++     G T LH A   GK  V SL        L+  S +  A+  S + P       
Sbjct: 1838 DVNXQDAYGDTALHDA--IGKRAVKSLTSLSITLALISPSETSVASMSSIMQP*R----- 1680

Query: 592  DNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQ---------MD---IATSLLEYGAD 639
                 A+ L      P +A+      L    K            MD   +   LL   A+
Sbjct: 1679 -----AMCL------PRSASCTNVDRLWT*GKMMGFLHFTWLL*MDTRMLQQHLLRNRAE 1533

Query: 640  ANAVTRQGIASVHLAAQEGHVDMVSLLLSRNANVNLSNKSGLTPLHLA------AQEDR- 692
             +    +    + LA  +GH  ++ LL+   A++N+S++ G T LHLA      A ED  
Sbjct: 1532 VDIRNNRQQTPLLLAVSQGHSSLIELLVHAQADINVSDEDGDTCLHLALMRQTVATEDSS 1353

Query: 693  --------------------VNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFL 732
                                  +A  L  QGA + A  + G  PL V     + + V  L
Sbjct: 1352 RMLDSIRSQLGMGEDEAQTGAAIACYLAQQGASLTACNQQGKXPLDV---TTDTRTVEIL 1182

Query: 733  LQHSAKVNA 741
             Q + +  A
Sbjct: 1181 QQFATEFCA 1155

 Score = 51.6 bits (122), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 53/217 (24%), Positives = 96/217 (44%), Gaps = 15/217 (6%)
 Frame = -3

Query: 88   KKGNTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVRFLLDNGA 147
            + G+TALH ++   Q +V+++L++ GA +NA +  G + L++A  + H++ V  LL+ G 
Sbjct: 2018 RDGDTALHYSAFGNQPDVLQLLLSKGAKINALNNGGCSTLHVAVNKQHIKCVHVLLNXGC 1839

Query: 148  SQSLATEDGFTPLAVALQQGHDQVVSLLLENDTKGKVRLPALHIAARKDDTKAAALLLQ- 206
              +     G T L       HD +    +++ T   + L    I+  +    + + ++Q 
Sbjct: 1838 DVNXQDAYGDTAL-------HDAIGKRAVKSLTSLSITLAL--ISPSETSVASMSSIMQP 1686

Query: 207  ----------NDTNADV----ESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDI 252
                      + TN D         GF             +   LL   A VD       
Sbjct: 1685 *RAMCLPRSASCTNVDRLWT*GKMMGFLHFTWLL*MDTRMLQQHLLRNRAEVDIRNNRQQ 1506

Query: 253  TPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLH 289
            TPL +A  +G++++++LL+   A I+    DG T LH
Sbjct: 1505 TPLLLAVSQGHSSLIELLVHAQADINVSDEDGDTCLH 1395

 Score = 48.9 bits (115), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 70/304 (23%), Positives = 122/304 (40%), Gaps = 22/304 (7%)
 Frame = -3

Query: 282  RDGLTPLHCGARSGHEQVVEMLLDRSAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNV 341
            RDG T LH  A      V+++LL + A I +    G S LH+A    H+ CV +LL    
Sbjct: 2018 RDGDTALHYSAFGNQPDVLQLLLSKGAKINALNNGGCSTLHVAVNKQHIKCVHVLLNXGC 1839

Query: 342  PVD--DVTNDYLTALHVAAHCGHYKVAKVLLDKKASPNAKALNGFTPLHIACKKNRIRVM 399
             V+  D   D  TALH A            + K+A  +  +L+  T   I+  +  +  M
Sbjct: 1838 DVNXQDAYGD--TALHDA------------IGKRAVKSLTSLS-ITLALISPSETSVASM 1704

Query: 400  ELLLKHGASIQAVTESGLTPIHV----AAFMGHVNIV-----------SQLMHHGASPNT 444
              +++   ++     +  T +         MG ++               L+ + A  + 
Sbjct: 1703 SSIMQP*RAMCLPRSASCTNVDRLWT*GKMMGFLHFTWLL*MDTRMLQQHLLRNRAEVDI 1524

Query: 445  TNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQ 504
             N R +T L +A   G + ++  LV   A +    +D  T LH++           L++Q
Sbjct: 1523 RNNRQQTPLLLAVSQGHSSLIELLVHAQADINVSDEDGDTCLHLA-----------LMRQ 1377

Query: 505  GASPNAAT---TSGYTPLHLAAREGHED--VAAFLLDHGASLSITTKKGFTPLHVAAKYG 559
              +   ++    S  + L +   E      +A +L   GASL+   ++G  PL V     
Sbjct: 1376 TVATEDSSRMLDSIRSQLGMGEDEAQTGAAIACYLAQQGASLTACNQQGKXPLDVTTDTR 1197

Query: 560  KLEV 563
             +E+
Sbjct: 1196 TVEI 1185

 Score = 45.8 bits (107), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 27/76 (35%), Positives = 44/76 (57%)
 Frame = -3

Query: 678  KSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSA 737
            + G T LH +A  ++ +V ++L+++GA ++A    G + LHV  +  +IK V+ LL    
Sbjct: 2018 RDGDTALHYSAFGNQPDVLQLLLSKGAKINALNNGGCSTLHVAVNKQHIKCVHVLLNXGC 1839

Query: 738  KVNAKTKNGYTALHQA 753
             VN +   G TALH A
Sbjct: 1838 DVNXQDAYGDTALHDA 1791

 Score = 39.3 bits (90), Expect = 0.013,   Method: Compositional matrix adjust.
 Identities = 23/76 (30%), Positives = 39/76 (51%)
 Frame = -3

Query: 249  RNDITPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRSA 308
            R+  T LH ++     ++++LLL +GAKI+A    G + LH      H + V +LL+   
Sbjct: 2018 RDGDTALHYSAFGNQPDVLQLLLSKGAKINALNNGGCSTLHVAVNKQHIKCVHVLLNXGC 1839

Query: 309  PILSKTKNGLSPLHMA 324
             +  +   G + LH A
Sbjct: 1838 DVNXQDAYGDTALHDA 1791

 Score = 38.5 bits (88), Expect = 0.024,   Method: Compositional matrix adjust.
 Identities = 26/78 (33%), Positives = 35/78 (44%), Gaps = 2/78 (2%)
 Frame = -3

Query: 713  GYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTALHQAAQQGHTHIINVLLQNNASP 772
            G T LH         ++  LL   AK+NA    G + LH A  + H   ++VLL      
Sbjct: 2012 GDTALHYSAFGNQPDVLQLLLSKGAKINALNNGGCSTLHVAVNKQHIKCVHVLLNXGCDV 1833

Query: 773  NELTVNGNTAL--AIARR 788
            N     G+TAL  AI +R
Sbjct: 1832 NXQDAYGDTALHDAIGKR 1779

 Score = 38.1 bits (87), Expect = 0.031,   Method: Compositional matrix adjust.
 Identities = 24/76 (31%), Positives = 39/76 (51%)
 Frame = -3

Query: 55   QNGLNALHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQAEVVKVLVTNGA 114
            ++G  ALH ++     +V+  LL + A ++A    G + LH+A      + V VL+  G 
Sbjct: 2018 RDGDTALHYSAFGNQPDVLQLLLSKGAKINALNNGGCSTLHVAVNKQHIKCVHVLLNXGC 1839

Query: 115  NVNAQSQNGFTPLYMA 130
            +VN Q   G T L+ A
Sbjct: 1838 DVNXQDAYGDTALHDA 1791

 Score = 35.8 bits (81), Expect = 0.14,   Method: Compositional matrix adjust.
 Identities = 70/320 (21%), Positives = 115/320 (35%), Gaps = 26/320 (8%)
 Frame = -3

Query: 416  GLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQV 475
            G T +H +AF    +++  L+  GA  N  N  G + LH+A      + V  L+  G  V
Sbjct: 2012 GDTALHYSAFGNQPDVLQLLLSKGAKINALNNGGCSTLHVAVNKQHIKCVHVLLNXGCDV 1833

Query: 476  EAKAKDDQTPLH--ISARLGKADIVQQLLQQGASPNAATTSGYTPLHLAAREGHEDVAAF 533
              +     T LH  I  R  K+     +     SP+  + +  + +    R       A 
Sbjct: 1832 NXQDAYGDTALHDAIGKRAVKSLTSLSITLALISPSETSVASMSSIMQP*R-------AM 1674

Query: 534  LLDHGASLSITTK-------KGFTPLHVAAKYGKLEVASLLLQKSASPDAAGKSGLTPLH 586
             L   AS +   +        GF             +   LL+  A  D       TPL 
Sbjct: 1673 CLPRSASCTNVDRLWT*GKMMGFLHFTWLL*MDTRMLQQHLLRNRAEVDIRNNRQQTPLL 1494

Query: 587  VAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKN---------QMDIATSLLEYG 637
            +A    +  +  LL+   A  + + ++G T LH+A  +           +D   S L  G
Sbjct: 1493 LAVSQGHSSLIELLVHAQADINVSDEDGDTCLHLALMRQTVATEDSSRMLDSIRSQLGMG 1314

Query: 638  AD--------ANAVTRQGIASVHLAAQEGHVDMVSLLLSRNANVNLSNKSGLTPLHLAAQ 689
             D        A  + +QG AS+    Q+G   +     +R   +     +     +   +
Sbjct: 1313 EDEAQTGAAIACYLAQQG-ASLTACNQQGKXPLDVTTDTRTVEILQQFATEFCASNTKIE 1137

Query: 690  EDRVNVAEVLVNQGAHVDAQ 709
            E+   + EV  NQ A V  Q
Sbjct: 1136 EEEGGLCEVCCNQAATVTFQ 1077

 Score = 34.7 bits (78), Expect = 0.35,   Method: Compositional matrix adjust.
 Identities = 28/124 (22%), Positives = 54/124 (43%), Gaps = 27/124 (21%)
 Frame = -3

Query: 44   IKNGVDVNICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKGNTALHIA------ 97
            ++N  +V+I N      L LA  +GH  ++  L+  +A+++ + + G+T LH+A      
Sbjct: 1550 LRNRAEVDIRNNRQQTPLLLAVSQGHSSLIELLVHAQADINVSDEDGDTCLHLALMRQTV 1371

Query: 98   ----------SLAGQ-----------AEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHL 136
                      S+  Q           A +   L   GA++ A +Q G  PL +      +
Sbjct: 1370 ATEDSSRMLDSIRSQLGMGEDEAQTGAAIACYLAQQGASLTACNQQGKXPLDVTTDTRTV 1191

Query: 137  EVVR 140
            E+++
Sbjct: 1190 EILQ 1179

 Score = 34.7 bits (78), Expect = 0.35,   Method: Compositional matrix adjust.
 Identities = 18/54 (33%), Positives = 28/54 (51%)
 Frame = -3

Query: 44   IKNGVDVNICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKGNTALHIA 97
            +  G  +N  N  G + LH+A  + H++ V  LL    +V+     G+TALH A
Sbjct: 1952 LSKGAKINALNNGGCSTLHVAVNKQHIKCVHVLLNXGCDVNXQDAYGDTALHDA 1791

 Score = 32.0 bits (71), Expect = 2.1,   Method: Compositional matrix adjust.
 Identities = 38/175 (21%), Positives = 63/175 (36%)
 Frame = -3

Query: 270  LLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRSAPILSKTKNGLSPLHMATQGDH 329
            LL   A++D +     TPL      GH  ++E+L+   A I    ++G + LH+A     
Sbjct: 1553 LLRNRAEVDIRNNRQQTPLLLAVSQGHSSLIELLVHAQADINVSDEDGDTCLHLA----- 1389

Query: 330  LNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKASPNAKALNGFTPLHI 389
                  L++  V  +D +                   ++L   ++          T   I
Sbjct: 1388 ------LMRQTVATEDSS-------------------RMLDSIRSQLGMGEDEAQTGAAI 1284

Query: 390  ACKKNRIRVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNT 444
            AC          L + GAS+ A  + G  P+ V      V I+ Q      + NT
Sbjct: 1283 AC---------YLAQQGASLTACNQQGKXPLDVTTDTRTVEILQQFATEFCASNT 1146

 Score = 32.0 bits (71), Expect = 2.2,   Method: Compositional matrix adjust.
 Identities = 18/56 (32%), Positives = 31/56 (55%)
 Frame = -3

Query: 109  LVTNGANVNAQSQNGFTPLYMAAQENHLEVVRFLLDNGASQSLATEDGFTPLAVAL 164
            L+ N A V+ ++    TPL +A  + H  ++  L+   A  +++ EDG T L +AL
Sbjct: 1553 LLRNRAEVDIRNNRQQTPLLLAVSQGHSSLIELLVHAQADINVSDEDGDTCLHLAL 1386

 Score = 30.8 bits (68), Expect = 4.6,   Method: Compositional matrix adjust.
 Identities = 21/78 (26%), Positives = 38/78 (48%), Gaps = 2/78 (2%)
 Frame = -2

Query: 695  VAEVLVNQ-GAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAK-VNAKTKNGYTALHQ 752
            + + LVN  G     + K G+  LH     GN+     +L    + V+ +  +G++ALH 
Sbjct: 1770 IIDKLVNYPGIDFTFRNKRGFNVLHHAALKGNVFATERVLHKCRQIVDLRKDDGFSALHL 1591

Query: 753  AAQQGHTHIINVLLQNNA 770
            AA  GH  +   L++ ++
Sbjct: 1590 AALNGHKDVAAALIEESS 1537
>38834
          Length = 496

 Score = 57.0 bits (136), Expect = 6e-08,   Method: Compositional matrix adjust.
 Identities = 33/120 (27%), Positives = 59/120 (49%)
 Frame = -1

Query: 389 IACKKNRIRVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVR 448
           IAC    + + E+L + G  I  V  +G TP H++ +    +I   L+   A  NT N  
Sbjct: 496 IACSSGHLDIAEMLHRRGVQINVVNINGYTPXHLSVYFNKFDITHFLVKINAEINTVNNA 317

Query: 449 GETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASP 508
           G+T +++AA  G ++++  +V  G +V     D      IS R+ K D+++ +     +P
Sbjct: 316 GQTPVYLAALRGNSKILALMVNAGCKVNGLVSD------ISTRINK-DLLEYIQYLARNP 158

 Score = 57.0 bits (136), Expect = 7e-08,   Method: Composition-based stats.
 Identities = 26/89 (29%), Positives = 46/89 (51%)
 Frame = -1

Query: 653 LAAQEGHVDMVSLLLSRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKM 712
           +A   GH+D+  +L  R   +N+ N +G TP HL+   ++ ++   LV   A ++     
Sbjct: 496 IACSSGHLDIAEMLHRRGVQINVVNINGYTPXHLSVYFNKFDITHFLVKINAEINTVNNA 317

Query: 713 GYTPLHVGCHYGNIKIVNFLLQHSAKVNA 741
           G TP+++    GN KI+  ++    KVN 
Sbjct: 316 GQTPVYLAALRGNSKILALMVNAGCKVNG 230

 Score = 56.2 bits (134), Expect = 1e-07,   Method: Composition-based stats.
 Identities = 26/88 (29%), Positives = 48/88 (54%)
 Frame = -1

Query: 356 VAAHCGHYKVAKVLLDKKASPNAKALNGFTPLHIACKKNRIRVMELLLKHGASIQAVTES 415
           +A   GH  +A++L  +    N   +NG+TP H++   N+  +   L+K  A I  V  +
Sbjct: 496 IACSSGHLDIAEMLHRRGVQINVVNINGYTPXHLSVYFNKFDITHFLVKINAEINTVNNA 317

Query: 416 GLTPIHVAAFMGHVNIVSQLMHHGASPN 443
           G TP+++AA  G+  I++ +++ G   N
Sbjct: 316 GQTPVYLAALRGNSKILALMVNAGCKVN 233

 Score = 53.9 bits (128), Expect = 6e-07,   Method: Composition-based stats.
 Identities = 23/84 (27%), Positives = 46/84 (54%)
 Frame = -1

Query: 521 LAAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVASLLLQKSASPDAAGKS 580
           +A   GH D+A  L   G  +++    G+TP H++  + K ++   L++ +A  +    +
Sbjct: 496 IACSSGHLDIAEMLHRRGVQINVVNINGYTPXHLSVYFNKFDITHFLVKINAEINTVNNA 317

Query: 581 GLTPLHVAAHYDNQKVALLLLDQG 604
           G TP+++AA   N K+  L+++ G
Sbjct: 316 GQTPVYLAALRGNSKILALMVNAG 245

 Score = 50.8 bits (120), Expect = 4e-06,   Method: Composition-based stats.
 Identities = 28/89 (31%), Positives = 40/89 (44%)
 Frame = -1

Query: 620 IAAKKNQMDIATSLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLSRNANVNLSNKS 679
           IA     +DIA  L   G   N V   G    HL+      D+   L+  NA +N  N +
Sbjct: 496 IACSSGHLDIAEMLHRRGVQINVVNINGYTPXHLSVYFNKFDITHFLVKINAEINTVNNA 317

Query: 680 GLTPLHLAAQEDRVNVAEVLVNQGAHVDA 708
           G TP++LAA      +  ++VN G  V+ 
Sbjct: 316 GQTPVYLAALRGNSKILALMVNAGCKVNG 230

 Score = 50.1 bits (118), Expect = 7e-06,   Method: Composition-based stats.
 Identities = 24/98 (24%), Positives = 53/98 (54%)
 Frame = -1

Query: 686 LAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKN 745
           +A     +++AE+L  +G  ++     GYTP H+  ++    I +FL++ +A++N     
Sbjct: 496 IACSSGHLDIAEMLHRRGVQINVVNINGYTPXHLSVYFNKFDITHFLVKINAEINTVNNA 317

Query: 746 GYTALHQAAQQGHTHIINVLLQNNASPNELTVNGNTAL 783
           G T ++ AA +G++ I+ +++      N L  + +T +
Sbjct: 316 GQTPVYLAALRGNSKILALMVNAGCKVNGLVSDISTRI 203

 Score = 49.7 bits (117), Expect = 1e-05,   Method: Composition-based stats.
 Identities = 25/88 (28%), Positives = 44/88 (50%)
 Frame = -1

Query: 455 MAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTS 514
           +A  SG  ++   L + G Q+     +  TP H+S    K DI   L++  A  N    +
Sbjct: 496 IACSSGHLDIAEMLHRRGVQINVVNINGYTPXHLSVYFNKFDITHFLVKINAEINTVNNA 317

Query: 515 GYTPLHLAAREGHEDVAAFLLDHGASLS 542
           G TP++LAA  G+  + A +++ G  ++
Sbjct: 316 GQTPVYLAALRGNSKILALMVNAGCKVN 233

 Score = 48.1 bits (113), Expect = 3e-05,   Method: Composition-based stats.
 Identities = 27/87 (31%), Positives = 46/87 (52%)
 Frame = -1

Query: 588 AAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATSLLEYGADANAVTRQG 647
           + H D   +A +L  +G   +    NGYTP H++   N+ DI   L++  A+ N V   G
Sbjct: 484 SGHLD---IAEMLHRRGVQINVVNINGYTPXHLSVYFNKFDITHFLVKINAEINTVNNAG 314

Query: 648 IASVHLAAQEGHVDMVSLLLSRNANVN 674
              V+LAA  G+  +++L+++    VN
Sbjct: 313 QTPVYLAALRGNSKILALMVNAGCKVN 233

 Score = 47.4 bits (111), Expect = 5e-05,   Method: Composition-based stats.
 Identities = 24/81 (29%), Positives = 42/81 (51%)
 Frame = -1

Query: 488 ISARLGKADIVQQLLQQGASPNAATTSGYTPLHLAAREGHEDVAAFLLDHGASLSITTKK 547
           I+   G  DI + L ++G   N    +GYTP HL+      D+  FL+   A ++     
Sbjct: 496 IACSSGHLDIAEMLHRRGVQINVVNINGYTPXHLSVYFNKFDITHFLVKINAEINTVNNA 317

Query: 548 GFTPLHVAAKYGKLEVASLLL 568
           G TP+++AA  G  ++ +L++
Sbjct: 316 GQTPVYLAALRGNSKILALMV 254

 Score = 47.4 bits (111), Expect = 6e-05,   Method: Compositional matrix adjust.
 Identities = 30/117 (25%), Positives = 59/117 (50%)
 Frame = -1

Query: 31  AARAGHLEKALDYIKNGVDVNICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKG 90
           A  +GHL+ A    + GV +N+ N NG    HL+      ++   L++  A ++     G
Sbjct: 493 ACSSGHLDIAEMLHRRGVQINVVNINGYTPXHLSVYFNKFDITHFLVKINAEINTVNNAG 314

Query: 91  NTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVRFLLDNGA 147
            T +++A+L G ++++ ++V  G  VN    +  T +     ++ LE +++L  N A
Sbjct: 313 QTPVYLAALRGNSKILALMVNAGCKVNGLVSDISTRI----NKDLLEYIQYLARNPA 155

 Score = 45.1 bits (105), Expect = 2e-04,   Method: Composition-based stats.
 Identities = 21/93 (22%), Positives = 48/93 (51%)
 Frame = -1

Query: 191 IAARKDDTKAAALLLQNDTNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFTARN 250
           IA        A +L +     +V + +G+TP H++ ++   ++   L+   A ++     
Sbjct: 496 IACSSGHLDIAEMLHRRGVQINVVNINGYTPXHLSVYFNKFDITHFLVKINAEINTVNNA 317

Query: 251 DITPLHVASKRGNANMVKLLLDRGAKIDAKTRD 283
             TP+++A+ RGN+ ++ L+++ G K++    D
Sbjct: 316 GQTPVYLAALRGNSKILALMVNAGCKVNGLVSD 218

 Score = 44.7 bits (104), Expect = 4e-04,   Method: Composition-based stats.
 Identities = 21/86 (24%), Positives = 46/86 (53%)
 Frame = -1

Query: 96  IASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVRFLLDNGASQSLATED 155
           IA  +G  ++ ++L   G  +N  + NG+TP +++   N  ++  FL+   A  +     
Sbjct: 496 IACSSGHLDIAEMLHRRGVQINVVNINGYTPXHLSVYFNKFDITHFLVKINAEINTVNNA 317

Query: 156 GFTPLAVALQQGHDQVVSLLLENDTK 181
           G TP+ +A  +G+ ++++L++    K
Sbjct: 316 GQTPVYLAALRGNSKILALMVNAGCK 239

 Score = 41.2 bits (95), Expect = 0.004,   Method: Composition-based stats.
 Identities = 19/84 (22%), Positives = 42/84 (50%)
 Frame = -1

Query: 63  LASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQAEVVKVLVTNGANVNAQSQN 122
           +A   GH+++   L +R   ++     G T  H++    + ++   LV   A +N  +  
Sbjct: 496 IACSSGHLDIAEMLHRRGVQINVVNINGYTPXHLSVYFNKFDITHFLVKINAEINTVNNA 317

Query: 123 GFTPLYMAAQENHLEVVRFLLDNG 146
           G TP+Y+AA   + +++  +++ G
Sbjct: 316 GQTPVYLAALRGNSKILALMVNAG 245

 Score = 39.7 bits (91), Expect = 0.010,   Method: Composition-based stats.
 Identities = 22/85 (25%), Positives = 41/85 (48%)
 Frame = -1

Query: 294 SGHEQVVEMLLDRSAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTA 353
           SGH  + EML  R   I     NG +P H++   +  +    L++ N  ++ V N   T 
Sbjct: 484 SGHLDIAEMLHRRGVQINVVNINGYTPXHLSVYFNKFDITHFLVKINAEINTVNNAGQTP 305

Query: 354 LHVAAHCGHYKVAKVLLDKKASPNA 378
           +++AA  G+ K+  ++++     N 
Sbjct: 304 VYLAALRGNSKILALMVNAGCKVNG 230

 Score = 39.3 bits (90), Expect = 0.014,   Method: Composition-based stats.
 Identities = 19/90 (21%), Positives = 42/90 (46%)
 Frame = -1

Query: 554 VAAKYGKLEVASLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKN 613
           +A   G L++A +L ++    +    +G TP H++ +++   +   L+   A  +     
Sbjct: 496 IACSSGHLDIAEMLHRRGVQINVVNINGYTPXHLSVYFNKFDITHFLVKINAEINTVNNA 317

Query: 614 GYTPLHIAAKKNQMDIATSLLEYGADANAV 643
           G TP+++AA +    I   ++  G   N +
Sbjct: 316 GQTPVYLAALRGNSKILALMVNAGCKVNGL 227

 Score = 39.3 bits (90), Expect = 0.016,   Method: Composition-based stats.
 Identities = 26/117 (22%), Positives = 55/117 (47%), Gaps = 1/117 (0%)
 Frame = -1

Query: 224 IAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRGNANMVKLLLDRGAKIDAKTRD 283
           IA   G++++A +L  R   ++    N  TP H++      ++   L+   A+I+     
Sbjct: 496 IACSSGHLDIAEMLHRRGVQINVVNINGYTPXHLSVYFNKFDITHFLVKINAEINTVNNA 317

Query: 284 GLTPLHCGARSGHEQVVEMLLDRSAPILSKTKNGL-SPLHMATQGDHLNCVQLLLQH 339
           G TP++  A  G+ +++ ++++    +     NGL S +      D L  +Q L ++
Sbjct: 316 GQTPVYLAALRGNSKILALMVNAGCKV-----NGLVSDISTRINKDLLEYIQYLARN 161
>15772
          Length = 1282

 Score = 56.6 bits (135), Expect = 9e-08,   Method: Composition-based stats.
 Identities = 33/91 (36%), Positives = 44/91 (48%)
 Frame = -3

Query: 253  TPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRSAPILS 312
            T LH A ++G    ++LLLD GAK  A+T  G TP HC A       +  L     P+  
Sbjct: 1172 TALHWACQKGFVECIRLLLDHGAKGTARTDTGWTPAHCAAECNRVTALRALHAALVPVDL 993

Query: 313  KTKNGLSPLHMATQGDHLNCVQLLLQHNVPV 343
              K G +P  +AT   H +C + LLQ    V
Sbjct: 992  TDKYGDTPRRIATLYGHRDCARYLLQAEAEV 900

 Score = 55.5 bits (132), Expect = 2e-07,   Method: Composition-based stats.
 Identities = 33/96 (34%), Positives = 48/96 (50%)
 Frame = -3

Query: 385  TPLHIACKKNRIRVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNT 444
            T LH AC+K  +  + LLL HGA   A T++G TP H AA    V  +  L       + 
Sbjct: 1172 TALHWACQKGFVECIRLLLDHGAKGTARTDTGWTPAHCAAECNRVTALRALHAALVPVDL 993

Query: 445  TNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAK 480
            T+  G+T   +A   G  +  RYL+Q  A+V  + +
Sbjct: 992  TDKYGDTPRRIATLYGHRDCARYLLQAEAEVAERRR 885

 Score = 54.7 bits (130), Expect = 4e-07,   Method: Composition-based stats.
 Identities = 45/135 (33%), Positives = 63/135 (46%), Gaps = 5/135 (3%)
 Frame = -3

Query: 453  LHMAARSGQAEVVRYLVQDGA-QVEAKAKD--DQTPLHISARLGKADIVQQLLQQGASPN 509
            LH AA +G  + +   V+ G   V  K  D  ++T LH + + G  + ++ LL  GA   
Sbjct: 1274 LHDAASTGDYDALEDYVKSGIYDVNLKDPDAGNKTALHWACQKGFVECIRLLLDHGAKGT 1095

Query: 510  AATTSGYTPLHLAAREGHEDVAAFLLDHGA--SLSITTKKGFTPLHVAAKYGKLEVASLL 567
            A T +G+TP H AA      V A    H A   + +T K G TP  +A  YG  + A  L
Sbjct: 1094 ARTDTGWTPAHCAAECNR--VTALRALHAALVPVDLTDKYGDTPRRIATLYGHRDCARYL 921

Query: 568  LQKSASPDAAGKSGL 582
            LQ  A      + GL
Sbjct: 920  LQAEAEVAERRRKGL 876

 Score = 53.9 bits (128), Expect = 5e-07,   Method: Composition-based stats.
 Identities = 32/97 (32%), Positives = 46/97 (47%)
 Frame = -3

Query: 650  SVHLAAQEGHVDMVSLLLSRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQ 709
            ++H A Q+G V+ + LLL   A       +G TP H AA+ +RV     L      VD  
Sbjct: 1169 ALHWACQKGFVECIRLLLDHGAKGTARTDTGWTPAHCAAECNRVTALRALHAALVPVDLT 990

Query: 710  TKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNG 746
             K G TP  +   YG+     +LLQ  A+V  + + G
Sbjct: 989  DKYGDTPRRIATLYGHRDCARYLLQAEAEVAERRRKG 879

 Score = 50.8 bits (120), Expect = 4e-06,   Method: Composition-based stats.
 Identities = 38/126 (30%), Positives = 55/126 (43%), Gaps = 6/126 (4%)
 Frame = -3

Query: 486  LHISARLGKADIVQQLLQQG------ASPNAATTSGYTPLHLAAREGHEDVAAFLLDHGA 539
            LH +A  G  D ++  ++ G        P+A      T LH A ++G  +    LLDHGA
Sbjct: 1274 LHDAASTGDYDALEDYVKSGIYDVNLKDPDAGNK---TALHWACQKGFVECIRLLLDHGA 1104

Query: 540  SLSITTKKGFTPLHVAAKYGKLEVASLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALL 599
              +  T  G+TP H AA+  ++     L       D   K G TP  +A  Y ++  A  
Sbjct: 1103 KGTARTDTGWTPAHCAAECNRVTALRALHAALVPVDLTDKYGDTPRRIATLYGHRDCARY 924

Query: 600  LLDQGA 605
            LL   A
Sbjct: 923  LLQAEA 906

 Score = 49.7 bits (117), Expect = 1e-05,   Method: Composition-based stats.
 Identities = 37/136 (27%), Positives = 58/136 (42%), Gaps = 6/136 (4%)
 Frame = -3

Query: 420  IHVAAFMGHVNIVSQLMHHG------ASPNTTNVRGETALHMAARSGQAEVVRYLVQDGA 473
            +H AA  G  + +   +  G        P+  N   +TALH A + G  E +R L+  GA
Sbjct: 1274 LHDAASTGDYDALEDYVKSGIYDVNLKDPDAGN---KTALHWACQKGFVECIRLLLDHGA 1104

Query: 474  QVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLAAREGHEDVAAF 533
            +  A+     TP H +A   +   ++ L       +     G TP  +A   GH D A +
Sbjct: 1103 KGTARTDTGWTPAHCAAECNRVTALRALHAALVPVDLTDKYGDTPRRIATLYGHRDCARY 924

Query: 534  LLDHGASLSITTKKGF 549
            LL   A ++   +KG 
Sbjct: 923  LLQAEAEVAERRRKGL 876

 Score = 47.8 bits (112), Expect = 4e-05,   Method: Composition-based stats.
 Identities = 33/124 (26%), Positives = 58/124 (46%), Gaps = 3/124 (2%)
 Frame = -3

Query: 61   LHLASKEGHVEVVSELLQR---EANVDAATKKGNTALHIASLAGQAEVVKVLVTNGANVN 117
            LH A+  G  + + + ++    + N+        TALH A   G  E +++L+ +GA   
Sbjct: 1274 LHDAASTGDYDALEDYVKSGIYDVNLKDPDAGNKTALHWACQKGFVECIRLLLDHGAKGT 1095

Query: 118  AQSQNGFTPLYMAAQENHLEVVRFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLLE 177
            A++  G+TP + AA+ N +  +R L        L  + G TP  +A   GH      LL+
Sbjct: 1094 ARTDTGWTPAHCAAECNRVTALRALHAALVPVDLTDKYGDTPRRIATLYGHRDCARYLLQ 915

Query: 178  NDTK 181
             + +
Sbjct: 914  AEAE 903

 Score = 44.7 bits (104), Expect = 3e-04,   Method: Composition-based stats.
 Identities = 27/89 (30%), Positives = 40/89 (44%)
 Frame = -3

Query: 352  TALHVAAHCGHYKVAKVLLDKKASPNAKALNGFTPLHIACKKNRIRVMELLLKHGASIQA 411
            TALH A   G  +  ++LLD  A   A+   G+TP H A + NR+  +  L      +  
Sbjct: 1172 TALHWACQKGFVECIRLLLDHGAKGTARTDTGWTPAHCAAECNRVTALRALHAALVPVDL 993

Query: 412  VTESGLTPIHVAAFMGHVNIVSQLMHHGA 440
              + G TP  +A   GH +    L+   A
Sbjct: 992  TDKYGDTPRRIATLYGHRDCARYLLQAEA 906

 Score = 44.3 bits (103), Expect = 4e-04,   Method: Composition-based stats.
 Identities = 28/98 (28%), Positives = 44/98 (44%)
 Frame = -3

Query: 188  ALHIAARKDDTKAAALLLQNDTNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFT 247
            ALH A +K   +   LLL +       + +G+TP H AA    +     L      VD T
Sbjct: 1169 ALHWACQKGFVECIRLLLDHGAKGTARTDTGWTPAHCAAECNRVTALRALHAALVPVDLT 990

Query: 248  ARNDITPLHVASKRGNANMVKLLLDRGAKIDAKTRDGL 285
             +   TP  +A+  G+ +  + LL   A++  + R GL
Sbjct: 989  DKYGDTPRRIATLYGHRDCARYLLQAEAEVAERRRKGL 876

 Score = 43.5 bits (101), Expect = 8e-04,   Method: Composition-based stats.
 Identities = 34/108 (31%), Positives = 44/108 (40%)
 Frame = -3

Query: 574  PDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATSL 633
            PDA  K   T LH A      +   LLLD GA   A    G+TP H AA+ N++    +L
Sbjct: 1190 PDAGNK---TALHWACQKGFVECIRLLLDHGAKGTARTDTGWTPAHCAAECNRVTALRAL 1020

Query: 634  LEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLSRNANVNLSNKSGL 681
                   +   + G     +A   GH D    LL   A V    + GL
Sbjct: 1019 HAALVPVDLTDKYGDTPRRIATLYGHRDCARYLLQAEAEVAERRRKGL 876

 Score = 42.0 bits (97), Expect = 0.002,   Method: Composition-based stats.
 Identities = 35/124 (28%), Positives = 60/124 (48%), Gaps = 4/124 (3%)
 Frame = -3

Query: 255  LHVASKRGNANMVKLLLDRGA-KIDAKTRDG--LTPLHCGARSGHEQVVEMLLDRSAPIL 311
            LH A+  G+ + ++  +  G   ++ K  D    T LH   + G  + + +LLD  A   
Sbjct: 1274 LHDAASTGDYDALEDYVKSGIYDVNLKDPDAGNKTALHWACQKGFVECIRLLLDHGAKGT 1095

Query: 312  SKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDY-LTALHVAAHCGHYKVAKVLL 370
            ++T  G +P H A + + +  ++ L    VPV D+T+ Y  T   +A   GH   A+ LL
Sbjct: 1094 ARTDTGWTPAHCAAECNRVTALRALHAALVPV-DLTDKYGDTPRRIATLYGHRDCARYLL 918

Query: 371  DKKA 374
              +A
Sbjct: 917  QAEA 906

 Score = 39.7 bits (91), Expect = 0.012,   Method: Composition-based stats.
 Identities = 37/127 (29%), Positives = 51/127 (40%), Gaps = 3/127 (2%)
 Frame = -3

Query: 651  VHLAAQEGHVDMVS-LLLSRNANVNLSNKSG--LTPLHLAAQEDRVNVAEVLVNQGAHVD 707
            +H AA  G  D +   + S   +VNL +      T LH A Q+  V    +L++ GA   
Sbjct: 1274 LHDAASTGDYDALEDYVKSGIYDVNLKDPDAGNKTALHWACQKGFVECIRLLLDHGAKGT 1095

Query: 708  AQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTALHQAAQQGHTHIINVLLQ 767
            A+T  G+TP H       +  +  L      V+   K G T    A   GH      LLQ
Sbjct: 1094 ARTDTGWTPAHCAAECNRVTALRALHAALVPVDLTDKYGDTPRRIATLYGHRDCARYLLQ 915

Query: 768  NNASPNE 774
              A   E
Sbjct: 914  AEAEVAE 894

 Score = 37.7 bits (86), Expect = 0.036,   Method: Composition-based stats.
 Identities = 37/135 (27%), Positives = 51/135 (37%), Gaps = 5/135 (3%)
 Frame = -3

Query: 189  LHIAARKDDTKAAALLLQN---DTNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVD 245
            LH AA   D  A    +++   D N         T LH A   G +    LLL+  A   
Sbjct: 1274 LHDAASTGDYDALEDYVKSGIYDVNLKDPDAGNKTALHWACQKGFVECIRLLLDHGA--K 1101

Query: 246  FTARNDI--TPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEML 303
             TAR D   TP H A++      ++ L      +D   + G TP       GH      L
Sbjct: 1100 GTARTDTGWTPAHCAAECNRVTALRALHAALVPVDLTDKYGDTPRRIATLYGHRDCARYL 921

Query: 304  LDRSAPILSKTKNGL 318
            L   A +  + + GL
Sbjct: 920  LQAEAEVAERRRKGL 876
>28691
          Length = 562

 Score = 54.7 bits (130), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 40/102 (39%), Positives = 61/102 (59%), Gaps = 6/102 (5%)
 Frame = +1

Query: 54  NQNGLNALHLASKEGHVEVVSELLQREANVDA---ATKKGNTALHIASLAGQAEV--VKV 108
           +++GL ALHLA+K  HV+ +  L+Q  A+V+A   +T KGNTALH A   G + V  V  
Sbjct: 109 SKSGLPALHLAAKNKHVDCIPVLVQAGADVNAKGPSTIKGNTALHEAVSVGASNVDSVDA 288

Query: 109 LVTNGANVNAQSQNGFTPLYMAAQENHLEVV-RFLLDNGASQ 149
           L++ GA+ N  ++ G T   +A++  +  +V RF    G SQ
Sbjct: 289 LLSCGADQNIXNEKGETAYDLASKAGYENIVKRFAAAMGQSQ 414

 Score = 48.9 bits (115), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 35/94 (37%), Positives = 50/94 (53%), Gaps = 5/94 (5%)
 Frame = +1

Query: 674 NLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQ---TKMGYTPLHVGCHYG--NIKI 728
           ++ +KSGL  LHLAA+   V+   VLV  GA V+A+   T  G T LH     G  N+  
Sbjct: 100 SVESKSGLPALHLAAKNKHVDCIPVLVQAGADVNAKGPSTIKGNTALHEAVSVGASNVDS 279

Query: 729 VNFLLQHSAKVNAKTKNGYTALHQAAQQGHTHII 762
           V+ LL   A  N   + G TA   A++ G+ +I+
Sbjct: 280 VDALLSCGADQNIXNEKGETAYDLASKAGYENIV 381

 Score = 45.8 bits (107), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 38/103 (36%), Positives = 55/103 (53%), Gaps = 5/103 (4%)
 Frame = +1

Query: 600 LLDQGASPHAAAKNGYTPLHIAAKKNQMDIATSLLEYGADANA---VTRQGIASVHLAAQ 656
           LL Q AS  +  K+G   LH+AAK   +D    L++ GAD NA    T +G  ++H A  
Sbjct: 82  LLRQLASVES--KSGLPALHLAAKNKHVDCIPVLVQAGADVNAKGPSTIKGNTALHEAVS 255

Query: 657 EG--HVDMVSLLLSRNANVNLSNKSGLTPLHLAAQEDRVNVAE 697
            G  +VD V  LLS  A+ N+ N+ G T   LA++    N+ +
Sbjct: 256 VGASNVDSVDALLSCGADQNIXNEKGETAYDLASKAGYENIVK 384

 Score = 45.1 bits (105), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 30/87 (34%), Positives = 45/87 (51%), Gaps = 5/87 (5%)
 Frame = +1

Query: 449 GETALHMAARSGQAEVVRYLVQDGAQVEAKAKD---DQTPLHISARLGKADI--VQQLLQ 503
           G  ALH+AA++   + +  LVQ GA V AK        T LH +  +G +++  V  LL 
Sbjct: 118 GLPALHLAAKNKHVDCIPVLVQAGADVNAKGPSTIKGNTALHEAVSVGASNVDSVDALLS 297

Query: 504 QGASPNAATTSGYTPLHLAAREGHEDV 530
            GA  N     G T   LA++ G+E++
Sbjct: 298 CGADQNIXNEKGETAYDLASKAGYENI 378

 Score = 44.7 bits (104), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 30/92 (32%), Positives = 47/92 (51%), Gaps = 5/92 (5%)
 Frame = +1

Query: 709 QTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAK---TKNGYTALHQAAQQGHTHI--IN 763
           ++K G   LH+     ++  +  L+Q  A VNAK   T  G TALH+A   G +++  ++
Sbjct: 106 ESKSGLPALHLAAKNKHVDCIPVLVQAGADVNAKGPSTIKGNTALHEAVSVGASNVDSVD 285

Query: 764 VLLQNNASPNELTVNGNTALAIARRLGYISVV 795
            LL   A  N     G TA  +A + GY ++V
Sbjct: 286 ALLSCGADQNIXNEKGETAYDLASKAGYENIV 381

 Score = 39.3 bits (90), Expect = 0.015,   Method: Compositional matrix adjust.
 Identities = 31/98 (31%), Positives = 48/98 (48%), Gaps = 5/98 (5%)
 Frame = +1

Query: 211 ADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDI---TPLHVASKRGNANM- 266
           A VESKSG   LH+AA   +++   +L+   A V+    + I   T LH A   G +N+ 
Sbjct: 97  ASVESKSGLPALHLAAKNKHVDCIPVLVQAGADVNAKGPSTIKGNTALHEAVSVGASNVD 276

Query: 267 -VKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEML 303
            V  LL  GA  +     G T     +++G+E +V+  
Sbjct: 277 SVDALLSCGADQNIXNEKGETAYDLASKAGYENIVKRF 390

 Score = 34.7 bits (78), Expect = 0.31,   Method: Compositional matrix adjust.
 Identities = 32/90 (35%), Positives = 43/90 (47%), Gaps = 7/90 (7%)
 Frame = +1

Query: 186 LPALHIAARKDDTKAAALLLQNDTNADVESKS-----GFTPLHIAAHYGNINVATL--LL 238
           LPALH+AA+        +L+Q    ADV +K      G T LH A   G  NV ++  LL
Sbjct: 121 LPALHLAAKNKHVDCIPVLVQ--AGADVNAKGPSTIKGNTALHEAVSVGASNVDSVDALL 294

Query: 239 NRAAAVDFTARNDITPLHVASKRGNANMVK 268
           +  A  +       T   +ASK G  N+VK
Sbjct: 295 SCGADQNIXNEKGETAYDLASKAGYENIVK 384

 Score = 33.5 bits (75), Expect = 0.68,   Method: Compositional matrix adjust.
 Identities = 27/85 (31%), Positives = 40/85 (47%), Gaps = 5/85 (5%)
 Frame = +1

Query: 313 KTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYL---TALHVAAHCGHYKVAKV- 368
           ++K+GL  LH+A +  H++C+ +L+Q    V+      +   TALH A   G   V  V 
Sbjct: 106 ESKSGLPALHLAAKNKHVDCIPVLVQAGADVNAKGPSTIKGNTALHEAVSVGASNVDSVD 285

Query: 369 -LLDKKASPNAKALNGFTPLHIACK 392
            LL   A  N     G T   +A K
Sbjct: 286 ALLSCGADQNIXNEKGETAYDLASK 360

 Score = 33.5 bits (75), Expect = 0.69,   Method: Compositional matrix adjust.
 Identities = 30/124 (24%), Positives = 51/124 (41%), Gaps = 2/124 (1%)
 Frame = +1

Query: 542 SITTKKGFTPLHVAAKYGKLEVASLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLL 601
           S+ +K G   LH+AAK   ++   +L+Q  A  +A G S +                   
Sbjct: 100 SVESKSGLPALHLAAKNKHVDCIPVLVQAGADVNAKGPSTI------------------- 222

Query: 602 DQGASPHAAAKNGYTPLH--IAAKKNQMDIATSLLEYGADANAVTRQGIASVHLAAQEGH 659
                       G T LH  ++   + +D   +LL  GAD N    +G  +  LA++ G+
Sbjct: 223 -----------KGNTALHEAVSVGASNVDSVDALLSCGADQNIXNEKGETAYDLASKAGY 369

Query: 660 VDMV 663
            ++V
Sbjct: 370 ENIV 381
>30463
          Length = 412

 Score = 54.7 bits (130), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 32/86 (37%), Positives = 45/86 (52%)
 Frame = -1

Query: 449 GETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASP 508
           G TA H+AA +G +  V  L   GA ++ +  D QTPLH+++  G  + V+ L+   AS 
Sbjct: 388 GYTATHLAAMNGHSNAVMVLNIMGASIDCRTVDKQTPLHLASSAGHIECVKCLVANKASL 209

Query: 509 NAATTSGYTPLHLAAREGHEDVAAFL 534
            A      T   LA + G  DVA FL
Sbjct: 208 TAEDAFSRTAYDLADQYGQNDVADFL 131

 Score = 53.9 bits (128), Expect = 6e-07,   Method: Compositional matrix adjust.
 Identities = 33/91 (36%), Positives = 51/91 (56%), Gaps = 2/91 (2%)
 Frame = -1

Query: 87  TKKGNTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVRFLLDNG 146
           T  G TA H+A++ G +  V VL   GA+++ ++ +  TPL++A+   H+E V+ L+ N 
Sbjct: 397 TPTGYTATHLAAMNGHSNAVMVLNIMGASIDCRTVDKQTPLHLASSAGHIECVKCLVANK 218

Query: 147 ASQSLATEDGFTPLAVAL--QQGHDQVVSLL 175
           A  SL  ED F+  A  L  Q G + V   L
Sbjct: 217 A--SLTAEDAFSRTAYDLADQYGQNDVADFL 131

 Score = 50.4 bits (119), Expect = 7e-06,   Method: Compositional matrix adjust.
 Identities = 33/86 (38%), Positives = 42/86 (48%)
 Frame = -1

Query: 57  GLNALHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQAEVVKVLVTNGANV 116
           G  A HLA+  GH   V  L    A++D  T    T LH+AS AG  E VK LV N A++
Sbjct: 388 GYTATHLAAMNGHSNAVMVLNIMGASIDCRTVDKQTPLHLASSAGHIECVKCLVANKASL 209

Query: 117 NAQSQNGFTPLYMAAQENHLEVVRFL 142
            A+     T   +A Q    +V  FL
Sbjct: 208 TAEDAFSRTAYDLADQYGQNDVADFL 131

 Score = 49.3 bits (116), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 30/89 (33%), Positives = 47/89 (52%)
 Frame = -1

Query: 413 TESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDG 472
           T +G T  H+AA  GH N V  L   GAS +   V  +T LH+A+ +G  E V+ LV + 
Sbjct: 397 TPTGYTATHLAAMNGHSNAVMVLNIMGASIDCRTVDKQTPLHLASSAGHIECVKCLVANK 218

Query: 473 AQVEAKAKDDQTPLHISARLGKADIVQQL 501
           A + A+    +T   ++ + G+ D+   L
Sbjct: 217 ASLTAEDAFSRTAYDLADQYGQNDVADFL 131

 Score = 47.8 bits (112), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 32/89 (35%), Positives = 40/89 (44%)
 Frame = -1

Query: 512 TTSGYTPLHLAAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVASLLLQKS 571
           T +GYT  HLAA  GH +    L   GAS+   T    TPLH+A+  G +E    L+   
Sbjct: 397 TPTGYTATHLAAMNGHSNAVMVLNIMGASIDCRTVDKQTPLHLASSAGHIECVKCLVANK 218

Query: 572 ASPDAAGKSGLTPLHVAAHYDNQKVALLL 600
           AS  A      T   +A  Y    VA  L
Sbjct: 217 ASLTAEDAFSRTAYDLADQYGQNDVADFL 131

 Score = 44.3 bits (103), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 29/84 (34%), Positives = 43/84 (51%)
 Frame = -1

Query: 484 TPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLAAREGHEDVAAFLLDHGASLSI 543
           T  H++A  G ++ V  L   GAS +  T    TPLHLA+  GH +    L+ + ASL+ 
Sbjct: 382 TATHLAAMNGHSNAVMVLNIMGASIDCRTVDKQTPLHLASSAGHIECVKCLVANKASLTA 203

Query: 544 TTKKGFTPLHVAAKYGKLEVASLL 567
                 T   +A +YG+ +VA  L
Sbjct: 202 EDAFSRTAYDLADQYGQNDVADFL 131

 Score = 43.9 bits (102), Expect = 6e-04,   Method: Compositional matrix adjust.
 Identities = 30/91 (32%), Positives = 42/91 (46%)
 Frame = -1

Query: 675 LSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQ 734
           L   +G T  HLAA     N   VL   GA +D +T    TPLH+    G+I+ V  L+ 
Sbjct: 403 LETPTGYTATHLAAMNGHSNAVMVLNIMGASIDCRTVDKQTPLHLASSAGHIECVKCLVA 224

Query: 735 HSAKVNAKTKNGYTALHQAAQQGHTHIINVL 765
           + A + A+     TA   A Q G   + + L
Sbjct: 223 NKASLTAEDAFSRTAYDLADQYGQNDVADFL 131

 Score = 43.9 bits (102), Expect = 6e-04,   Method: Compositional matrix adjust.
 Identities = 24/74 (32%), Positives = 40/74 (54%)
 Frame = -1

Query: 253 TPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRSAPILS 312
           T  H+A+  G++N V +L   GA ID +T D  TPLH  + +GH + V+ L+   A + +
Sbjct: 382 TATHLAAMNGHSNAVMVLNIMGASIDCRTVDKQTPLHLASSAGHIECVKCLVANKASLTA 203

Query: 313 KTKNGLSPLHMATQ 326
           +     +   +A Q
Sbjct: 202 EDAFSRTAYDLADQ 161

 Score = 43.9 bits (102), Expect = 6e-04,   Method: Compositional matrix adjust.
 Identities = 27/86 (31%), Positives = 42/86 (48%)
 Frame = -1

Query: 383 GFTPLHIACKKNRIRVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASP 442
           G+T  H+A        + +L   GASI   T    TP+H+A+  GH+  V  L+ + AS 
Sbjct: 388 GYTATHLAAMNGHSNAVMVLNIMGASIDCRTVDKQTPLHLASSAGHIECVKCLVANKASL 209

Query: 443 NTTNVRGETALHMAARSGQAEVVRYL 468
              +    TA  +A + GQ +V  +L
Sbjct: 208 TAEDAFSRTAYDLADQYGQNDVADFL 131

 Score = 42.4 bits (98), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 26/89 (29%), Positives = 40/89 (44%)
 Frame = -1

Query: 644 TRQGIASVHLAAQEGHVDMVSLLLSRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQG 703
           T  G  + HLAA  GH + V +L    A+++       TPLHLA+    +   + LV   
Sbjct: 397 TPTGYTATHLAAMNGHSNAVMVLNIMGASIDCRTVDKQTPLHLASSAGHIECVKCLVANK 218

Query: 704 AHVDAQTKMGYTPLHVGCHYGNIKIVNFL 732
           A + A+     T   +   YG   + +FL
Sbjct: 217 ASLTAEDAFSRTAYDLADQYGQNDVADFL 131

 Score = 42.0 bits (97), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 27/91 (29%), Positives = 44/91 (48%)
 Frame = -1

Query: 213 VESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRGNANMVKLLLD 272
           +E+ +G+T  H+AA  G+ N   +L    A++D    +  TPLH+AS  G+   VK L+ 
Sbjct: 403 LETPTGYTATHLAAMNGHSNAVMVLNIMGASIDCRTVDKQTPLHLASSAGHIECVKCLVA 224

Query: 273 RGAKIDAKTRDGLTPLHCGARSGHEQVVEML 303
             A + A+     T      + G   V + L
Sbjct: 223 NKASLTAEDAFSRTAYDLADQYGQNDVADFL 131

 Score = 38.9 bits (89), Expect = 0.020,   Method: Compositional matrix adjust.
 Identities = 20/58 (34%), Positives = 31/58 (53%)
 Frame = -1

Query: 280 KTRDGLTPLHCGARSGHEQVVEMLLDRSAPILSKTKNGLSPLHMATQGDHLNCVQLLL 337
           +T  G T  H  A +GH   V +L    A I  +T +  +PLH+A+   H+ CV+ L+
Sbjct: 400 ETPTGYTATHLAAMNGHSNAVMVLNIMGASIDCRTVDKQTPLHLASSAGHIECVKCLV 227

 Score = 37.4 bits (85), Expect = 0.050,   Method: Compositional matrix adjust.
 Identities = 23/57 (40%), Positives = 31/57 (54%)
 Frame = -1

Query: 742 KTKNGYTALHQAAQQGHTHIINVLLQNNASPNELTVNGNTALAIARRLGYISVVDTL 798
           +T  GYTA H AA  GH++ + VL    AS +  TV+  T L +A   G+I  V  L
Sbjct: 400 ETPTGYTATHLAAMNGHSNAVMVLNIMGASIDCRTVDKQTPLHLASSAGHIECVKCL 230

 Score = 36.6 bits (83), Expect = 0.084,   Method: Compositional matrix adjust.
 Identities = 25/86 (29%), Positives = 40/86 (46%)
 Frame = -1

Query: 614 GYTPLHIAAKKNQMDIATSLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLSRNANV 673
           GYT  H+AA     +    L   GA  +  T      +HLA+  GH++ V  L++  A++
Sbjct: 388 GYTATHLAAMNGHSNAVMVLNIMGASIDCRTVDKQTPLHLASSAGHIECVKCLVANKASL 209

Query: 674 NLSNKSGLTPLHLAAQEDRVNVAEVL 699
              +    T   LA Q  + +VA+ L
Sbjct: 208 TAEDAFSRTAYDLADQYGQNDVADFL 131

 Score = 36.6 bits (83), Expect = 0.098,   Method: Compositional matrix adjust.
 Identities = 28/87 (32%), Positives = 42/87 (48%)
 Frame = -1

Query: 352 TALHVAAHCGHYKVAKVLLDKKASPNAKALNGFTPLHIACKKNRIRVMELLLKHGASIQA 411
           TA H+AA  GH     VL    AS + + ++  TPLH+A     I  ++ L+ + AS+ A
Sbjct: 382 TATHLAAMNGHSNAVMVLNIMGASIDCRTVDKQTPLHLASSAGHIECVKCLVANKASLTA 203

Query: 412 VTESGLTPIHVAAFMGHVNIVSQLMHH 438
                 T   +A   G  N V+  +HH
Sbjct: 202 EDAFSRTAYDLADQYGQ-NDVADFLHH 125

 Score = 35.4 bits (80), Expect = 0.19,   Method: Compositional matrix adjust.
 Identities = 23/67 (34%), Positives = 33/67 (49%)
 Frame = -1

Query: 313 KTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDK 372
           +T  G +  H+A    H N V +L      +D  T D  T LH+A+  GH +  K L+  
Sbjct: 400 ETPTGYTATHLAAMNGHSNAVMVLNIMGASIDCRTVDKQTPLHLASSAGHIECVKCLVAN 221

Query: 373 KASPNAK 379
           KAS  A+
Sbjct: 220 KASLTAE 200

 Score = 34.3 bits (77), Expect = 0.49,   Method: Compositional matrix adjust.
 Identities = 21/60 (35%), Positives = 29/60 (48%)
 Frame = -1

Query: 119 QSQNGFTPLYMAAQENHLEVVRFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLLEN 178
           ++  G+T  ++AA   H   V  L   GAS    T D  TPL +A   GH + V  L+ N
Sbjct: 400 ETPTGYTATHLAAMNGHSNAVMVLNIMGASIDCRTVDKQTPLHLASSAGHIECVKCLVAN 221
>21751
          Length = 643

 Score = 38.1 bits (87), Expect(2) = 5e-07,   Method: Compositional matrix adjust.
 Identities = 20/63 (31%), Positives = 35/63 (55%), Gaps = 1/63 (1%)
 Frame = +3

Query: 616 TPLHIAAKKNQMDIATSLLEYGADANAVTRQGIAS-VHLAAQEGHVDMVSLLLSRNANVN 674
           +PLH+A  +  + +   LLE+G D N      + S +H A +   +DM++LL+   A++N
Sbjct: 84  SPLHVAILRKNVHLGRLLLEHGEDVNQTFNDSLESPIHQAVRNLDLDMINLLIEFGADLN 263

Query: 675 LSN 677
             N
Sbjct: 264 RPN 272

 Score = 35.4 bits (80), Expect(2) = 5e-07,   Method: Composition-based stats.
 Identities = 20/61 (32%), Positives = 35/61 (57%), Gaps = 8/61 (13%)
 Frame = +1

Query: 682 TPLHLA-AQEDRV--NVAEVLVNQGAHVDAQTKMG-----YTPLHVGCHYGNIKIVNFLL 733
           TP+ L+   ED +   +A+ L+  GA  + +T++      Y+PLH+ C  GN+  V FL+
Sbjct: 286 TPVGLSLIMEDPIATEIAKRLIVAGASANQRTRISFFQKTYSPLHIACFKGNLGFVRFLV 465

Query: 734 Q 734
           +
Sbjct: 466 E 468

 Score = 38.5 bits (88), Expect = 0.023,   Method: Compositional matrix adjust.
 Identities = 22/76 (28%), Positives = 39/76 (51%), Gaps = 1/76 (1%)
 Frame = +3

Query: 372 KKASPNAKALNGFTPLHIACKKNRIRVMELLLKHGASI-QAVTESGLTPIHVAAFMGHVN 430
           +  S + K     +PLH+A  +  + +  LLL+HG  + Q   +S  +PIH A     ++
Sbjct: 45  RTVSLDDKVFTSQSPLHVAILRKNVHLGRLLLEHGEDVNQTFNDSLESPIHQAVRNLDLD 224

Query: 431 IVSQLMHHGASPNTTN 446
           +++ L+  GA  N  N
Sbjct: 225 MINLLIEFGADLNRPN 272

 Score = 38.5 bits (88), Expect = 0.023,   Method: Compositional matrix adjust.
 Identities = 22/73 (30%), Positives = 37/73 (50%), Gaps = 1/73 (1%)
 Frame = +3

Query: 570 KSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGY-TPLHIAAKKNQMD 628
           ++ S D    +  +PLHVA    N  +  LLL+ G   +    +   +P+H A +   +D
Sbjct: 45  RTVSLDDKVFTSQSPLHVAILRKNVHLGRLLLEHGEDVNQTFNDSLESPIHQAVRNLDLD 224

Query: 629 IATSLLEYGADAN 641
           +   L+E+GAD N
Sbjct: 225 MINLLIEFGADLN 263

 Score = 37.0 bits (84), Expect = 0.072,   Method: Compositional matrix adjust.
 Identities = 20/72 (27%), Positives = 38/72 (52%), Gaps = 1/72 (1%)
 Frame = +3

Query: 240 RAAAVDFTARNDITPLHVASKRGNANMVKLLLDRGAKIDAKTRDGL-TPLHCGARSGHEQ 298
           R  ++D       +PLHVA  R N ++ +LLL+ G  ++    D L +P+H   R+    
Sbjct: 45  RTVSLDDKVFTSQSPLHVAILRKNVHLGRLLLEHGEDVNQTFNDSLESPIHQAVRNLDLD 224

Query: 299 VVEMLLDRSAPI 310
           ++ +L++  A +
Sbjct: 225 MINLLIEFGADL 260

 Score = 34.7 bits (78), Expect = 0.36,   Method: Compositional matrix adjust.
 Identities = 18/60 (30%), Positives = 36/60 (60%), Gaps = 1/60 (1%)
 Frame = +3

Query: 220 TPLHIAAHYGNINVATLLLNRAAAVDFTARNDI-TPLHVASKRGNANMVKLLLDRGAKID 278
           +PLH+A    N+++  LLL     V+ T  + + +P+H A +  + +M+ LL++ GA ++
Sbjct: 84  SPLHVAILRKNVHLGRLLLEHGEDVNQTFNDSLESPIHQAVRNLDLDMINLLIEFGADLN 263

 Score = 29.3 bits (64), Expect(2) = 1.00,   Method: Compositional matrix adjust.
 Identities = 21/81 (25%), Positives = 39/81 (48%), Gaps = 9/81 (11%)
 Frame = +3

Query: 501 LLQQGASPNAATT--------SGYTPLHLAAREGHEDVAAFLLDHGASLSITTKKGF-TP 551
           L+Q GA  +   T        +  +PLH+A    +  +   LL+HG  ++ T      +P
Sbjct: 12  LIQYGADVHQLRTVSLDDKVFTSQSPLHVAILRKNVHLGRLLLEHGEDVNQTFNDSLESP 191

Query: 552 LHVAAKYGKLEVASLLLQKSA 572
           +H A +   L++ +LL++  A
Sbjct: 192 IHQAVRNLDLDMINLLIEFGA 254

 Score = 22.3 bits (46), Expect(2) = 1.00,   Method: Composition-based stats.
 Identities = 14/46 (30%), Positives = 22/46 (47%), Gaps = 5/46 (10%)
 Frame = +1

Query: 595 KVALLLLDQGASPHAAAK-----NGYTPLHIAAKKNQMDIATSLLE 635
           ++A  L+  GAS +   +       Y+PLHIA  K  +     L+E
Sbjct: 331 EIAKRLIVAGASANQRTRISFFQKTYSPLHIACFKGNLGFVRFLVE 468

 Score = 31.6 bits (70), Expect = 2.7,   Method: Compositional matrix adjust.
 Identities = 19/69 (27%), Positives = 33/69 (47%), Gaps = 1/69 (1%)
 Frame = +3

Query: 706 VDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTA-LHQAAQQGHTHIINV 764
           +D +     +PLHV     N+ +   LL+H   VN    +   + +HQA +     +IN+
Sbjct: 57  LDDKVFTSQSPLHVAILRKNVHLGRLLLEHGEDVNQTFNDSLESPIHQAVRNLDLDMINL 236

Query: 765 LLQNNASPN 773
           L++  A  N
Sbjct: 237 LIEFGADLN 263
>22269
          Length = 1060

 Score = 33.9 bits (76), Expect(3) = 6e-06,   Method: Compositional matrix adjust.
 Identities = 23/63 (36%), Positives = 31/63 (49%)
 Frame = +1

Query: 594 QKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATSLLEYGADANAVTRQGIASVHL 653
            KV  LLL  GA+P+A  +   T  H+AA         +LL  GA AN +T     +V L
Sbjct: 10  HKVMGLLLKYGANPNAVDRYNVTAAHLAAHSGSAQCLKTLLIKGAKANCLTMVMPEAVRL 189

Query: 654 AAQ 656
            A+
Sbjct: 190 EAE 198

 Score = 33.5 bits (75), Expect(3) = 6e-06,   Method: Compositional matrix adjust.
 Identities = 16/49 (32%), Positives = 25/49 (51%)
 Frame = +2

Query: 719 VGCHYGNIKIVNFLLQHSAKVNAKTKNGYTALHQAAQQGHTHIINVLLQ 767
           +GC   N++    L+ H A  NA  +NG + L  AA  G    + +LL+
Sbjct: 323 LGCQKNNVECARILICHGADYNATDENGESPLFMAAAAGLPDSVMMLLK 469

 Score = 21.2 bits (43), Expect(3) = 6e-06,   Method: Compositional matrix adjust.
 Identities = 9/20 (45%), Positives = 13/20 (65%)
 Frame = +3

Query: 675 LSNKSGLTPLHLAAQEDRVN 694
           L+ +   TPLHLAA+   +N
Sbjct: 291 LAIRGKTTPLHLAARRTMLN 350

 Score = 37.4 bits (85), Expect = 0.059,   Method: Compositional matrix adjust.
 Identities = 18/42 (42%), Positives = 24/42 (57%)
 Frame = +1

Query: 633 LLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLSRNANVN 674
           LL+YGA+ NAV R  + + HLAA  G    +  LL + A  N
Sbjct: 28  LLKYGANPNAVDRYNVTAAHLAAHSGSAQCLKTLLIKGAKAN 153

 Score = 36.6 bits (83), Expect = 0.100,   Method: Compositional matrix adjust.
 Identities = 24/69 (34%), Positives = 34/69 (49%), Gaps = 2/69 (2%)
 Frame = +1

Query: 397 RVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMA 456
           +VM LLLK+GA+  AV    +T  H+AA  G    +  L+  GA  N   +    A+ + 
Sbjct: 13  KVMGLLLKYGANPNAVDRYNVTAAHLAAHSGSAQCLKTLLIKGAKANCLTMVMPEAVRLE 192

Query: 457 A--RSGQAE 463
           A  R G  E
Sbjct: 193 AEFRQGDCE 219

 Score = 36.2 bits (82), Expect = 0.13,   Method: Compositional matrix adjust.
 Identities = 16/40 (40%), Positives = 25/40 (62%)
 Frame = +2

Query: 104 EVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVRFLL 143
           E  ++L+ +GA+ NA  +NG +PL+MAA     + V  LL
Sbjct: 347 ECARILICHGADYNATDENGESPLFMAAAAGLPDSVMMLL 466

 Score = 36.2 bits (82), Expect = 0.13,   Method: Compositional matrix adjust.
 Identities = 16/44 (36%), Positives = 28/44 (63%)
 Frame = +1

Query: 431 IVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQ 474
           ++  L+ +GA+PN  +    TA H+AA SG A+ ++ L+  GA+
Sbjct: 16  VMGLLLKYGANPNAVDRYNVTAAHLAAHSGSAQCLKTLLIKGAK 147

 Score = 35.4 bits (80), Expect = 0.19,   Method: Compositional matrix adjust.
 Identities = 16/48 (33%), Positives = 27/48 (56%)
 Frame = +2

Query: 389 IACKKNRIRVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLM 436
           + C+KN +    +L+ HGA   A  E+G +P+ +AA  G  + V  L+
Sbjct: 323 LGCQKNNVECARILICHGADYNATDENGESPLFMAAAAGLPDSVMMLL 466

 Score = 32.0 bits (71), Expect = 2.0,   Method: Compositional matrix adjust.
 Identities = 20/63 (31%), Positives = 32/63 (50%), Gaps = 3/63 (4%)
 Frame = +2

Query: 428 HVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQ---VEAKAKDDQT 484
           +V     L+ HGA  N T+  GE+ L MAA +G  + V  L++       +   +K++ T
Sbjct: 341 NVECARILICHGADYNATDENGESPLFMAAAAGLPDSVMMLLKQALGFPILSIPSKENST 520

Query: 485 PLH 487
            LH
Sbjct: 521 ALH 529

 Score = 30.4 bits (67), Expect = 5.8,   Method: Compositional matrix adjust.
 Identities = 18/49 (36%), Positives = 27/49 (55%)
 Frame = +1

Query: 233 VATLLLNRAAAVDFTARNDITPLHVASKRGNANMVKLLLDRGAKIDAKT 281
           V  LLL   A  +   R ++T  H+A+  G+A  +K LL +GAK +  T
Sbjct: 16  VMGLLLKYGANPNAVDRYNVTAAHLAAHSGSAQCLKTLLIKGAKANCLT 162
>15359
          Length = 780

 Score = 50.1 bits (118), Expect = 9e-06,   Method: Compositional matrix adjust.
 Identities = 28/63 (44%), Positives = 37/63 (58%), Gaps = 4/63 (6%)
 Frame = +1

Query: 477 AKAKD---DQTPLHISARLGKADIVQQLLQQ-GASPNAATTSGYTPLHLAAREGHEDVAA 532
           AK KD     T LH +A+ GK ++V+ L  + G   N  +  GYTPLHLAA  GHED+  
Sbjct: 325 AKVKDIANGYTALHWAAKFGKPEVVKMLANKIGVEINQRSHGGYTPLHLAAIHGHEDIIE 504

Query: 533 FLL 535
            L+
Sbjct: 505 LLV 513

 Score = 49.3 bits (116), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 23/56 (41%), Positives = 36/56 (64%), Gaps = 1/56 (1%)
 Frame = +1

Query: 250 NDITPLHVASKRGNANMVKLLLDR-GAKIDAKTRDGLTPLHCGARSGHEQVVEMLL 304
           N  T LH A+K G   +VK+L ++ G +I+ ++  G TPLH  A  GHE ++E+L+
Sbjct: 346 NGYTALHWAAKFGKPEVVKMLANKIGVEINQRSHGGYTPLHLAAIHGHEDIIELLV 513

 Score = 47.8 bits (112), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 23/55 (41%), Positives = 35/55 (63%), Gaps = 1/55 (1%)
 Frame = +1

Query: 90  GNTALHIASLAGQAEVVKVLVTN-GANVNAQSQNGFTPLYMAAQENHLEVVRFLL 143
           G TALH A+  G+ EVVK+L    G  +N +S  G+TPL++AA   H +++  L+
Sbjct: 349 GYTALHWAAKFGKPEVVKMLANKIGVEINQRSHGGYTPLHLAAIHGHEDIIELLV 513

 Score = 43.5 bits (101), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 28/87 (32%), Positives = 43/87 (49%), Gaps = 2/87 (2%)
 Frame = +1

Query: 382 NGFTPLHIACKKNRIRVMELLL-KHGASIQAVTESGLTPIHVAAFMGHVNIVSQLM-HHG 439
           NG+T LH A K  +  V+++L  K G  I   +  G TP+H+AA  GH +I+  L+  + 
Sbjct: 346 NGYTALHWAAKFGKPEVVKMLANKIGVEINQRSHGGYTPLHLAAIHGHEDIIELLVTGYK 525

Query: 440 ASPNTTNVRGETALHMAARSGQAEVVR 466
           A  N  +  G+ A      S  +   R
Sbjct: 526 ADANIRDYSGKKAKQYLKNSASSRAQR 606

 Score = 43.1 bits (100), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 26/70 (37%), Positives = 40/70 (57%), Gaps = 2/70 (2%)
 Frame = +1

Query: 613 NGYTPLHIAAKKNQMDIATSLL-EYGADANAVTRQGIASVHLAAQEGHVDMVSLLLS-RN 670
           NGYT LH AAK  + ++   L  + G + N  +  G   +HLAA  GH D++ LL++   
Sbjct: 346 NGYTALHWAAKFGKPEVVKMLANKIGVEINQRSHGGYTPLHLAAIHGHEDIIELLVTGYK 525

Query: 671 ANVNLSNKSG 680
           A+ N+ + SG
Sbjct: 526 ADANIRDYSG 555

 Score = 42.7 bits (99), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 21/55 (38%), Positives = 30/55 (54%), Gaps = 1/55 (1%)
 Frame = +1

Query: 713 GYTPLHVGCHYGNIKIVNFLLQH-SAKVNAKTKNGYTALHQAAQQGHTHIINVLL 766
           GYT LH    +G  ++V  L      ++N ++  GYT LH AA  GH  II +L+
Sbjct: 349 GYTALHWAAKFGKPEVVKMLANKIGVEINQRSHGGYTPLHLAAIHGHEDIIELLV 513

 Score = 42.4 bits (98), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 22/55 (40%), Positives = 34/55 (61%), Gaps = 1/55 (1%)
 Frame = +1

Query: 449 GETALHMAARSGQAEVVRYLVQD-GAQVEAKAKDDQTPLHISARLGKADIVQQLL 502
           G TALH AA+ G+ EVV+ L    G ++  ++    TPLH++A  G  DI++ L+
Sbjct: 349 GYTALHWAAKFGKPEVVKMLANKIGVEINQRSHGGYTPLHLAAIHGHEDIIELLV 513

 Score = 42.0 bits (97), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 35/118 (29%), Positives = 61/118 (51%), Gaps = 15/118 (12%)
 Frame = +1

Query: 647 GIASVHLAAQEGHVDMVSL---------LLSRNANV----NLSNKSGLTPLHLAAQEDRV 693
           G A V L+ +E    +VS          LL++NA +    +++N  G T LH AA+  + 
Sbjct: 217 GTAYVTLSPEEKEWMLVSATADYHEMFRLLNKNARLAKVKDIAN--GYTALHWAAKFGKP 390

Query: 694 NVAEVLVNQ-GAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQ-HSAKVNAKTKNGYTA 749
            V ++L N+ G  ++ ++  GYTPLH+   +G+  I+  L+  + A  N +  +G  A
Sbjct: 391 EVVKMLANKIGVEINQRSHGGYTPLHLAAIHGHEDIIELLVTGYKADANIRDYSGKKA 564

 Score = 40.0 bits (92), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 21/55 (38%), Positives = 33/55 (60%), Gaps = 1/55 (1%)
 Frame = +1

Query: 515 GYTPLHLAAREGHEDVAAFLLDH-GASLSITTKKGFTPLHVAAKYGKLEVASLLL 568
           GYT LH AA+ G  +V   L +  G  ++  +  G+TPLH+AA +G  ++  LL+
Sbjct: 349 GYTALHWAAKFGKPEVVKMLANKIGVEINQRSHGGYTPLHLAAIHGHEDIIELLV 513

 Score = 39.3 bits (90), Expect = 0.014,   Method: Compositional matrix adjust.
 Identities = 22/55 (40%), Positives = 32/55 (58%), Gaps = 1/55 (1%)
 Frame = +1

Query: 548 GFTPLHVAAKYGKLEVASLLLQK-SASPDAAGKSGLTPLHVAAHYDNQKVALLLL 601
           G+T LH AAK+GK EV  +L  K     +     G TPLH+AA + ++ +  LL+
Sbjct: 349 GYTALHWAAKFGKPEVVKMLANKIGVEINQRSHGGYTPLHLAAIHGHEDIIELLV 513

 Score = 39.3 bits (90), Expect = 0.014,   Method: Compositional matrix adjust.
 Identities = 20/56 (35%), Positives = 33/56 (58%), Gaps = 1/56 (1%)
 Frame = +1

Query: 122 NGFTPLYMAAQENHLEVVRFLLDN-GASQSLATEDGFTPLAVALQQGHDQVVSLLL 176
           NG+T L+ AA+    EVV+ L +  G   +  +  G+TPL +A   GH+ ++ LL+
Sbjct: 346 NGYTALHWAAKFGKPEVVKMLANKIGVEINQRSHGGYTPLHLAAIHGHEDIIELLV 513

 Score = 38.5 bits (88), Expect = 0.023,   Method: Compositional matrix adjust.
 Identities = 21/57 (36%), Positives = 34/57 (59%), Gaps = 1/57 (1%)
 Frame = +1

Query: 56  NGLNALHLASKEGHVEVVSELLQR-EANVDAATKKGNTALHIASLAGQAEVVKVLVT 111
           NG  ALH A+K G  EVV  L  +    ++  +  G T LH+A++ G  +++++LVT
Sbjct: 346 NGYTALHWAAKFGKPEVVKMLANKIGVEINQRSHGGYTPLHLAAIHGHEDIIELLVT 516

 Score = 31.2 bits (69), Expect = 3.7,   Method: Compositional matrix adjust.
 Identities = 23/78 (29%), Positives = 41/78 (52%), Gaps = 7/78 (8%)
 Frame = +1

Query: 168 HDQVVSLLLENDTKGKVR-----LPALHIAARKDDTKAAALLLQNDTNADVESKS--GFT 220
           + ++  LL +N    KV+       ALH AA+    +   +L  N    ++  +S  G+T
Sbjct: 283 YHEMFRLLNKNARLAKVKDIANGYTALHWAAKFGKPEVVKML-ANKIGVEINQRSHGGYT 459

Query: 221 PLHIAAHYGNINVATLLL 238
           PLH+AA +G+ ++  LL+
Sbjct: 460 PLHLAAIHGHEDIIELLV 513

 Score = 30.4 bits (67), Expect = 5.8,   Method: Compositional matrix adjust.
 Identities = 24/71 (33%), Positives = 38/71 (53%), Gaps = 4/71 (5%)
 Frame = +1

Query: 732 LLQHSAKVNAKTK---NGYTALHQAAQQGHTHIINVLLQN-NASPNELTVNGNTALAIAR 787
           LL  +A++ AK K   NGYTALH AA+ G   ++ +L        N+ +  G T L +A 
Sbjct: 301 LLNKNARL-AKVKDIANGYTALHWAAKFGKPEVVKMLANKIGVEINQRSHGGYTPLHLAA 477

Query: 788 RLGYISVVDTL 798
             G+  +++ L
Sbjct: 478 IHGHEDIIELL 510
>33144
          Length = 272

 Score = 49.7 bits (117), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 27/74 (36%), Positives = 41/74 (55%), Gaps = 1/74 (1%)
 Frame = +3

Query: 516 YTPLHLAAREGHEDVAAFLLDHG-ASLSITTKKGFTPLHVAAKYGKLEVASLLLQKSASP 574
           + PLHLAA  G   +A  L+  G  ++++  K   TPLH A +  +L +  LLL + A+P
Sbjct: 15  WAPLHLAAMNGRTAIAGVLVKKGEVAVNVVDKHKRTPLHYAVQTCELTIIDLLLGRDANP 194

Query: 575 DAAGKSGLTPLHVA 588
           +     G TP H+A
Sbjct: 195 NIQDVDGNTPTHLA 236

 Score = 48.1 bits (113), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 28/74 (37%), Positives = 41/74 (55%), Gaps = 1/74 (1%)
 Frame = +3

Query: 615 YTPLHIAAKKNQMDIATSLLEYGADA-NAVTRQGIASVHLAAQEGHVDMVSLLLSRNANV 673
           + PLH+AA   +  IA  L++ G  A N V +     +H A Q   + ++ LLL R+AN 
Sbjct: 15  WAPLHLAAMNGRTAIAGVLVKKGEVAVNVVDKHKRTPLHYAVQTCELTIIDLLLGRDANP 194

Query: 674 NLSNKSGLTPLHLA 687
           N+ +  G TP HLA
Sbjct: 195 NIQDVDGNTPTHLA 236

 Score = 44.7 bits (104), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 26/71 (36%), Positives = 38/71 (53%), Gaps = 1/71 (1%)
 Frame = +3

Query: 453 LHMAARSGQAEVVRYLVQDG-AQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAA 511
           LH+AA +G+  +   LV+ G   V    K  +TPLH + +  +  I+  LL + A+PN  
Sbjct: 24  LHLAAMNGRTAIAGVLVKKGEVAVNVVDKHKRTPLHYAVQTCELTIIDLLLGRDANPNIQ 203

Query: 512 TTSGYTPLHLA 522
              G TP HLA
Sbjct: 204 DVDGNTPTHLA 236

 Score = 42.7 bits (99), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 23/74 (31%), Positives = 38/74 (51%), Gaps = 1/74 (1%)
 Frame = +3

Query: 384 FTPLHIACKKNRIRVMELLLKHG-ASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASP 442
           + PLH+A    R  +  +L+K G  ++  V +   TP+H A     + I+  L+   A+P
Sbjct: 15  WAPLHLAAMNGRTAIAGVLVKKGEVAVNVVDKHKRTPLHYAVQTCELTIIDLLLGRDANP 194

Query: 443 NTTNVRGETALHMA 456
           N  +V G T  H+A
Sbjct: 195 NIQDVDGNTPTHLA 236

 Score = 42.4 bits (98), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 25/72 (34%), Positives = 39/72 (54%), Gaps = 1/72 (1%)
 Frame = +3

Query: 219 FTPLHIAAHYGNINVATLLLNRA-AAVDFTARNDITPLHVASKRGNANMVKLLLDRGAKI 277
           + PLH+AA  G   +A +L+ +   AV+   ++  TPLH A +     ++ LLL R A  
Sbjct: 15  WAPLHLAAMNGRTAIAGVLVKKGEVAVNVVDKHKRTPLHYAVQTCELTIIDLLLGRDANP 194

Query: 278 DAKTRDGLTPLH 289
           + +  DG TP H
Sbjct: 195 NIQDVDGNTPTH 230

 Score = 41.6 bits (96), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 25/74 (33%), Positives = 40/74 (54%), Gaps = 1/74 (1%)
 Frame = +3

Query: 549 FTPLHVAAKYGKLEVASLLLQKS-ASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASP 607
           + PLH+AA  G+  +A +L++K   + +   K   TPLH A       +  LLL + A+P
Sbjct: 15  WAPLHLAAMNGRTAIAGVLVKKGEVAVNVVDKHKRTPLHYAVQTCELTIIDLLLGRDANP 194

Query: 608 HAAAKNGYTPLHIA 621
           +    +G TP H+A
Sbjct: 195 NIQDVDGNTPTHLA 236

 Score = 40.8 bits (94), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 26/75 (34%), Positives = 38/75 (50%), Gaps = 1/75 (1%)
 Frame = +3

Query: 714 YTPLHVGCHYGNIKIVNFLLQHS-AKVNAKTKNGYTALHQAAQQGHTHIINVLLQNNASP 772
           + PLH+    G   I   L++     VN   K+  T LH A Q     II++LL  +A+P
Sbjct: 15  WAPLHLAAMNGRTAIAGVLVKKGEVAVNVVDKHKRTPLHYAVQTCELTIIDLLLGRDANP 194

Query: 773 NELTVNGNTALAIAR 787
           N   V+GNT   +A+
Sbjct: 195 NIQDVDGNTPTHLAQ 239

 Score = 40.4 bits (93), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 24/71 (33%), Positives = 38/71 (53%), Gaps = 1/71 (1%)
 Frame = +3

Query: 94  LHIASLAGQAEVVKVLVTNG-ANVNAQSQNGFTPLYMAAQENHLEVVRFLLDNGASQSLA 152
           LH+A++ G+  +  VLV  G   VN   ++  TPL+ A Q   L ++  LL   A+ ++ 
Sbjct: 24  LHLAAMNGRTAIAGVLVKKGEVAVNVVDKHKRTPLHYAVQTCELTIIDLLLGRDANPNIQ 203

Query: 153 TEDGFTPLAVA 163
             DG TP  +A
Sbjct: 204 DVDGNTPTHLA 236

 Score = 38.5 bits (88), Expect = 0.022,   Method: Compositional matrix adjust.
 Identities = 23/72 (31%), Positives = 39/72 (54%), Gaps = 1/72 (1%)
 Frame = +3

Query: 649 ASVHLAAQEGHVDMVSLLLSRN-ANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVD 707
           A +HLAA  G   +  +L+ +    VN+ +K   TPLH A Q   + + ++L+ + A+ +
Sbjct: 18  APLHLAAMNGRTAIAGVLVKKGEVAVNVVDKHKRTPLHYAVQTCELTIIDLLLGRDANPN 197

Query: 708 AQTKMGYTPLHV 719
            Q   G TP H+
Sbjct: 198 IQDVDGNTPTHL 233

 Score = 35.0 bits (79), Expect = 0.29,   Method: Compositional matrix adjust.
 Identities = 22/73 (30%), Positives = 36/73 (49%), Gaps = 1/73 (1%)
 Frame = +3

Query: 319 SPLHMATQGDHLNCVQLLLQHN-VPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKASPN 377
           +PLH+A          +L++   V V+ V     T LH A       +  +LL + A+PN
Sbjct: 18  APLHLAAMNGRTAIAGVLVKKGEVAVNVVDKHKRTPLHYAVQTCELTIIDLLLGRDANPN 197

Query: 378 AKALNGFTPLHIA 390
            + ++G TP H+A
Sbjct: 198 IQDVDGNTPTHLA 236

 Score = 33.9 bits (76), Expect = 0.57,   Method: Compositional matrix adjust.
 Identities = 24/71 (33%), Positives = 36/71 (50%)
 Frame = +3

Query: 30  RAARAGHLEKALDYIKNGVDVNICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKK 89
           R A AG L K     K  V VN+ +++    LH A +   + ++  LL R+AN +     
Sbjct: 48  RTAIAGVLVK-----KGEVAVNVVDKHKRTPLHYAVQTCELTIIDLLLGRDANPNIQDVD 212

Query: 90  GNTALHIASLA 100
           GNT  H+A +A
Sbjct: 213 GNTPTHLAQMA 245

 Score = 33.9 bits (76), Expect = 0.61,   Method: Compositional matrix adjust.
 Identities = 19/72 (26%), Positives = 38/72 (52%), Gaps = 1/72 (1%)
 Frame = +3

Query: 254 PLHVASKRGNANMVKLLLDRG-AKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRSAPILS 312
           PLH+A+  G   +  +L+ +G   ++   +   TPLH   ++    ++++LL R A    
Sbjct: 21  PLHLAAMNGRTAIAGVLVKKGEVAVNVVDKHKRTPLHYAVQTCELTIIDLLLGRDANPNI 200

Query: 313 KTKNGLSPLHMA 324
           +  +G +P H+A
Sbjct: 201 QDVDGNTPTHLA 236

 Score = 32.3 bits (72), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 23/71 (32%), Positives = 34/71 (47%), Gaps = 1/71 (1%)
 Frame = +3

Query: 189 LHIAARKDDTKAAALLLQ-NDTNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFT 247
           LH+AA    T  A +L++  +   +V  K   TPLH A     + +  LLL R A  +  
Sbjct: 24  LHLAAMNGRTAIAGVLVKKGEVAVNVVDKHKRTPLHYAVQTCELTIIDLLLGRDANPNIQ 203

Query: 248 ARNDITPLHVA 258
             +  TP H+A
Sbjct: 204 DVDGNTPTHLA 236
>17893
          Length = 453

 Score = 49.7 bits (117), Expect = 1e-05,   Method: Composition-based stats.
 Identities = 28/59 (47%), Positives = 33/59 (55%)
 Frame = -3

Query: 496 DIVQQLLQQGASPNAATTSGYTPLHLAAREGHEDVAAFLLDHGASLSITTKKGFTPLHV 554
           D V  LL+ GAS N    +G T LH AAR  H DV  +LLDHG ++      G T LHV
Sbjct: 178 DFVDSLLKNGASINIMDRTGQTLLHEAARAWHVDVTRWLLDHGINIDQPDYYGRTALHV 2

 Score = 43.9 bits (102), Expect = 5e-04,   Method: Composition-based stats.
 Identities = 32/105 (30%), Positives = 48/105 (45%), Gaps = 1/105 (0%)
 Frame = -3

Query: 583 TPLHVAAHYDNQKVALL-LLDQGASPHAAAKNGYTPLHIAAKKNQMDIATSLLEYGADAN 641
           T L+V+   D+ +  +   +D   SPH  AK              +D   SLL+ GA  N
Sbjct: 280 TRLNVSMVIDSNRALIQHFVDMADSPHEEAKI------------NLDFVDSLLKNGASIN 137

Query: 642 AVTRQGIASVHLAAQEGHVDMVSLLLSRNANVNLSNKSGLTPLHL 686
            + R G   +H AA+  HVD+   LL    N++  +  G T LH+
Sbjct: 136 IMDRTGQTLLHEAARAWHVDVTRWLLDHGINIDQPDYYGRTALHV 2

 Score = 43.9 bits (102), Expect = 5e-04,   Method: Composition-based stats.
 Identities = 21/53 (39%), Positives = 30/53 (56%)
 Frame = -3

Query: 44  IKNGVDVNICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKGNTALHI 96
           +KNG  +NI ++ G   LH A++  HV+V   LL    N+D     G TALH+
Sbjct: 160 LKNGASINIMDRTGQTLLHEAARAWHVDVTRWLLDHGINIDQPDYYGRTALHV 2

 Score = 43.1 bits (100), Expect = 0.001,   Method: Composition-based stats.
 Identities = 22/54 (40%), Positives = 33/54 (61%)
 Frame = -3

Query: 402 LLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHM 455
           LLK+GASI  +  +G T +H AA   HV++   L+ HG + +  +  G TALH+
Sbjct: 163 LLKNGASINIMDRTGQTLLHEAARAWHVDVTRWLLDHGINIDQPDYYGRTALHV 2

 Score = 42.4 bits (98), Expect = 0.002,   Method: Composition-based stats.
 Identities = 27/94 (28%), Positives = 48/94 (51%)
 Frame = -3

Query: 395 RIRVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALH 454
           R+ V  ++  + A IQ   +   +P   A    +++ V  L+ +GAS N  +  G+T LH
Sbjct: 277 RLNVSMVIDSNRALIQHFVDMADSPHEEAKI--NLDFVDSLLKNGASINIMDRTGQTLLH 104

Query: 455 MAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHI 488
            AAR+   +V R+L+  G  ++      +T LH+
Sbjct: 103 EAARAWHVDVTRWLLDHGINIDQPDYYGRTALHV 2

 Score = 37.7 bits (86), Expect = 0.043,   Method: Composition-based stats.
 Identities = 18/43 (41%), Positives = 29/43 (67%)
 Frame = -3

Query: 104 EVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVRFLLDNG 146
           + V  L+ NGA++N   + G T L+ AA+  H++V R+LLD+G
Sbjct: 178 DFVDSLLKNGASINIMDRTGQTLLHEAARAWHVDVTRWLLDHG 50

 Score = 37.4 bits (85), Expect = 0.048,   Method: Composition-based stats.
 Identities = 27/94 (28%), Positives = 47/94 (50%)
 Frame = -3

Query: 692 RVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTALH 751
           R+NV+ V+ +  A +     M  +P H      N+  V+ LL++ A +N   + G T LH
Sbjct: 277 RLNVSMVIDSNRALIQHFVDMADSP-HEEAKI-NLDFVDSLLKNGASINIMDRTGQTLLH 104

Query: 752 QAAQQGHTHIINVLLQNNASPNELTVNGNTALAI 785
           +AA+  H  +   LL +  + ++    G TAL +
Sbjct: 103 EAARAWHVDVTRWLLDHGINIDQPDYYGRTALHV 2

 Score = 35.8 bits (81), Expect = 0.17,   Method: Composition-based stats.
 Identities = 23/61 (37%), Positives = 28/61 (45%)
 Frame = -3

Query: 263 NANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRSAPILSKTKNGLSPLH 322
           N + V  LL  GA I+   R G T LH  AR+ H  V   LLD    I      G + LH
Sbjct: 184 NLDFVDSLLKNGASINIMDRTGQTLLHEAARAWHVDVTRWLLDHGINIDQPDYYGRTALH 5

Query: 323 M 323
           +
Sbjct: 4   V 2
>30978
          Length = 566

 Score = 48.5 bits (114), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 30/88 (34%), Positives = 43/88 (48%), Gaps = 1/88 (1%)
 Frame = -2

Query: 621 AAKKNQMDIATSLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLSR-NANVNLSNKS 679
             K  Q    T  L      N + + G   +H A   GH+D + +LLS     VN+ NK 
Sbjct: 550 CCKTRQH*FLTECLSNRVSVNGLDKAGSTPLHWAGHGGHMDCLQVLLSEPKCEVNVQNKL 371

Query: 680 GLTPLHLAAQEDRVNVAEVLVNQGAHVD 707
           G T LH AA ++ V   ++L+ +GA VD
Sbjct: 370 GDTALHSAAWKNHVEAVKMLLGKGARVD 287

 Score = 47.0 bits (110), Expect = 7e-05,   Method: Compositional matrix adjust.
 Identities = 36/129 (27%), Positives = 61/129 (47%), Gaps = 1/129 (0%)
 Frame = -2

Query: 390 ACKKNRIRVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHH-GASPNTTNVR 448
            CK  +   +   L +  S+  + ++G TP+H A   GH++ +  L+       N  N  
Sbjct: 550 CCKTRQH*FLTECLSNRVSVNGLDKAGSTPLHWAGHGGHMDCLQVLLSEPKCEVNVQNKL 371

Query: 449 GETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASP 508
           G+TALH AA     E V+ L+  GA+V+ +  + +    ++  L K   V  +L+Q A  
Sbjct: 370 GDTALHSAAWKNHVEAVKMLLGKGARVDLRNNEKK----LAVELTKDPEVAAMLRQAA-- 209

Query: 509 NAATTSGYT 517
               +S YT
Sbjct: 208 -GVQSSRYT 185

 Score = 42.4 bits (98), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 27/63 (42%), Positives = 35/63 (55%), Gaps = 3/63 (4%)
 Frame = -2

Query: 315 KNGLSPLHMATQGDHLNCVQLLLQH---NVPVDDVTNDYLTALHVAAHCGHYKVAKVLLD 371
           K G +PLH A  G H++C+Q+LL      V V +   D  TALH AA   H +  K+LL 
Sbjct: 478 KAGSTPLHWAGHGGHMDCLQVLLSEPKCEVNVQNKLGD--TALHSAAWKNHVEAVKMLLG 305

Query: 372 KKA 374
           K A
Sbjct: 304 KGA 296

 Score = 38.9 bits (89), Expect = 0.016,   Method: Compositional matrix adjust.
 Identities = 26/74 (35%), Positives = 37/74 (50%), Gaps = 1/74 (1%)
 Frame = -2

Query: 337 LQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDK-KASPNAKALNGFTPLHIACKKNR 395
           L + V V+ +     T LH A H GH    +VLL + K   N +   G T LH A  KN 
Sbjct: 511 LSNRVSVNGLDKAGSTPLHWAGHGGHMDCLQVLLSEPKCEVNVQNKLGDTALHSAAWKNH 332

Query: 396 IRVMELLLKHGASI 409
           +  +++LL  GA +
Sbjct: 331 VEAVKMLLGKGARV 290

 Score = 34.7 bits (78), Expect = 0.39,   Method: Compositional matrix adjust.
 Identities = 21/74 (28%), Positives = 35/74 (47%), Gaps = 1/74 (1%)
 Frame = -2

Query: 277 IDAKTRDGLTPLHCGARSGHEQVVEMLLDR-SAPILSKTKNGLSPLHMATQGDHLNCVQL 335
           ++   + G TPLH     GH   +++LL      +  + K G + LH A   +H+  V++
Sbjct: 493 VNGLDKAGSTPLHWAGHGGHMDCLQVLLSEPKCEVNVQNKLGDTALHSAAWKNHVEAVKM 314

Query: 336 LLQHNVPVDDVTND 349
           LL     VD   N+
Sbjct: 313 LLGKGARVDLRNNE 272

 Score = 31.2 bits (69), Expect = 3.4,   Method: Compositional matrix adjust.
 Identities = 17/36 (47%), Positives = 23/36 (63%)
 Frame = -2

Query: 49  DVNICNQNGLNALHLASKEGHVEVVSELLQREANVD 84
           +VN+ N+ G  ALH A+ + HVE V  LL + A VD
Sbjct: 394 EVNVQNKLGDTALHSAAWKNHVEAVKMLLGKGARVD 287
>27067
          Length = 409

 Score = 46.6 bits (109), Expect = 8e-05,   Method: Compositional matrix adjust.
 Identities = 35/125 (28%), Positives = 60/125 (48%), Gaps = 9/125 (7%)
 Frame = +1

Query: 374 ASPNAKALNGFTPLHIACKKNRIRVMELLLKH-GASIQAVTESGLTPIHVAAFMGHVNIV 432
           A  N+K   G + +H A K N   ++  LL   G    AV  S  TP+  AA  G +  +
Sbjct: 1   ADINSK-FKGSSAVHEAIKVNNTDILRYLLTVPGLECNAVNASQKTPVMEAASRGRIECL 177

Query: 433 SQLMHHGASPNTTNVRGETALH--MAARSGQAEV------VRYLVQDGAQVEAKAKDDQT 484
           + L+ HG +    N+RG+TA+H  + +  G  E+      +  + + G  + A+     +
Sbjct: 178 TMLLDHGCNTEGENIRGKTAMHHCLLSCGGFVEIEDMVTCMDLVYKAGGNINAQDWFGTS 357

Query: 485 PLHIS 489
           PLH++
Sbjct: 358 PLHLA 372

 Score = 41.2 bits (95), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 35/130 (26%), Positives = 60/130 (46%), Gaps = 9/130 (6%)
 Frame = +1

Query: 473 AQVEAKAKDDQTPLHISARLGKADIVQQLLQQ-GASPNAATTSGYTPLHLAAREGHEDVA 531
           A + +K K   + +H + ++   DI++ LL   G   NA   S  TP+  AA  G  +  
Sbjct: 1   ADINSKFKG-SSAVHEAIKVNNTDILRYLLTVPGLECNAVNASQKTPVMEAASRGRIECL 177

Query: 532 AFLLDHGASLSITTKKGFTPLH--VAAKYGKLEV------ASLLLQKSASPDAAGKSGLT 583
             LLDHG +      +G T +H  + +  G +E+        L+ +   + +A    G +
Sbjct: 178 TMLLDHGCNTEGENIRGKTAMHHCLLSCGGFVEIEDMVTCMDLVYKAGGNINAQDWFGTS 357

Query: 584 PLHVAAHYDN 593
           PLH+A   +N
Sbjct: 358 PLHLAISTEN 387

 Score = 40.4 bits (93), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 26/99 (26%), Positives = 47/99 (47%), Gaps = 8/99 (8%)
 Frame = +1

Query: 47  GVDVNICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKGNTALH--IASLAGQAE 104
           G++ N  N +    +  A+  G +E ++ LL    N +    +G TA+H  + S  G  E
Sbjct: 97  GLECNAVNASQKTPVMEAASRGRIECLTMLLDHGCNTEGENIRGKTAMHHCLLSCGGFVE 276

Query: 105 V------VKVLVTNGANVNAQSQNGFTPLYMAAQENHLE 137
           +      + ++   G N+NAQ   G +PL++A    + E
Sbjct: 277 IEDMVTCMDLVYKAGGNINAQDWFGTSPLHLAISTENFE 393

 Score = 38.1 bits (87), Expect = 0.035,   Method: Compositional matrix adjust.
 Identities = 33/116 (28%), Positives = 56/116 (48%), Gaps = 9/116 (7%)
 Frame = +1

Query: 581 GLTPLHVAAHYDNQKVALLLLDQ-GASPHAAAKNGYTPLHIAAKKNQMDIATSLLEYGAD 639
           G + +H A   +N  +   LL   G   +A   +  TP+  AA + +++  T LL++G +
Sbjct: 25  GSSAVHEAIKVNNTDILRYLLTVPGLECNAVNASQKTPVMEAASRGRIECLTMLLDHGCN 204

Query: 640 ANAVTRQGIASVH--LAAQEGHV---DMVS---LLLSRNANVNLSNKSGLTPLHLA 687
                 +G  ++H  L +  G V   DMV+   L+     N+N  +  G +PLHLA
Sbjct: 205 TEGENIRGKTAMHHCLLSCGGFVEIEDMVTCMDLVYKAGGNINAQDWFGTSPLHLA 372

 Score = 37.7 bits (86), Expect = 0.044,   Method: Compositional matrix adjust.
 Identities = 35/127 (27%), Positives = 57/127 (44%), Gaps = 13/127 (10%)
 Frame = +1

Query: 211 ADVESK-SGFTPLHIAAHYGNINVATLLLN----RAAAVDFTARNDITPLHVASKRGNAN 265
           AD+ SK  G + +H A    N ++   LL        AV+ + +   TP+  A+ RG   
Sbjct: 1   ADINSKFKGSSAVHEAIKVNNTDILRYLLTVPGLECNAVNASQK---TPVMEAASRGRIE 171

Query: 266 MVKLLLDRGAKIDAKTRDGLTPLH-----CGARSGHEQVV---EMLLDRSAPILSKTKNG 317
            + +LLD G   + +   G T +H     CG     E +V   +++      I ++   G
Sbjct: 172 CLTMLLDHGCNTEGENIRGKTAMHHCLLSCGGFVEIEDMVTCMDLVYKAGGNINAQDWFG 351

Query: 318 LSPLHMA 324
            SPLH+A
Sbjct: 352 TSPLHLA 372

 Score = 31.6 bits (70), Expect = 3.1,   Method: Compositional matrix adjust.
 Identities = 19/61 (31%), Positives = 34/61 (55%), Gaps = 1/61 (1%)
 Frame = +1

Query: 89  KGNTALHIASLAGQAEVVKVLVTN-GANVNAQSQNGFTPLYMAAQENHLEVVRFLLDNGA 147
           KG++A+H A      ++++ L+T  G   NA + +  TP+  AA    +E +  LLD+G 
Sbjct: 22  KGSSAVHEAIKVNNTDILRYLLTVPGLECNAVNASQKTPVMEAASRGRIECLTMLLDHGC 201

Query: 148 S 148
           +
Sbjct: 202 N 204
>13900
          Length = 751

 Score = 45.1 bits (105), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 37/129 (28%), Positives = 64/129 (49%), Gaps = 8/129 (6%)
 Frame = +1

Query: 480 KDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLAAREGHE-DVAAFLLDHG 538
           +  Q+PLH++ R+      ++LL+ G+ P     SG TPL +A  +GHE +   F + + 
Sbjct: 274 RSGQSPLHLAVRVNDFHKAKKLLKLGSDPLLPDFSGITPLRMA--QGHEYNAIVFYMCYV 447

Query: 539 ASLSITTK-KGFTPLHVAAKYGKLEVASLLLQKSASPD------AAGKSGLTPLHVAAHY 591
             +++    +G T L  A +   L    +LL+  A+PD      + G++ L  L V   Y
Sbjct: 448 RDINVNVMVRGETTLQQAVRDNYLLGIQVLLRSGANPDLVVRMPSYGQNCLE-LAVMCRY 624

Query: 592 DNQKVALLL 600
            N   AL++
Sbjct: 625 VNAVRALIV 651

 Score = 40.0 bits (92), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 36/130 (27%), Positives = 57/130 (43%), Gaps = 4/130 (3%)
 Frame = +1

Query: 546 KKGFTPLHVAAKYGKLEVASLLLQKSASPDAAGKSGLTPLHVA-AHYDNQKVALLLLDQG 604
           + G +PLH+A +      A  LL+  + P     SG+TPL +A  H  N  V  +   + 
Sbjct: 274 RSGQSPLHLAVRVNDFHKAKKLLKLGSDPLLPDFSGITPLRMAQGHEYNAIVFYMCYVRD 453

Query: 605 ASPHAAAKNGYTPLHIAAKKNQMDIATSLLEYGADANAVTRQ---GIASVHLAAQEGHVD 661
            + +   + G T L  A + N +     LL  GA+ + V R    G   + LA    +V+
Sbjct: 454 INVNVMVR-GETTLQQAVRDNYLLGIQVLLRSGANPDLVVRMPSYGQNCLELAVMCRYVN 630

Query: 662 MVSLLLSRNA 671
            V  L+  N 
Sbjct: 631 AVRALIVHNC 660

 Score = 37.4 bits (85), Expect = 0.049,   Method: Compositional matrix adjust.
 Identities = 28/92 (30%), Positives = 44/92 (47%)
 Frame = +1

Query: 382 NGFTPLHIACKKNRIRVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGAS 441
           +G +PLH+A + N     + LLK G+       SG+TP+ +A    +  IV  + +    
Sbjct: 277 SGQSPLHLAVRVNDFHKAKKLLKLGSDPLLPDFSGITPLRMAQGHEYNAIVFYMCYVRDI 456

Query: 442 PNTTNVRGETALHMAARSGQAEVVRYLVQDGA 473
                VRGET L  A R      ++ L++ GA
Sbjct: 457 NVNVMVRGETTLQQAVRDNYLLGIQVLLRSGA 552

 Score = 33.5 bits (75), Expect = 0.80,   Method: Compositional matrix adjust.
 Identities = 33/131 (25%), Positives = 58/131 (44%), Gaps = 4/131 (3%)
 Frame = +1

Query: 214 ESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVA-SKRGNANMVKLLLD 272
           + +SG +PLH+A    + + A  LL   +       + ITPL +A     NA +  +   
Sbjct: 268 DPRSGQSPLHLAVRVNDFHKAKKLLKLGSDPLLPDFSGITPLRMAQGHEYNAIVFYMCYV 447

Query: 273 RGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRSAP---ILSKTKNGLSPLHMATQGDH 329
           R   ++   R G T L    R  +   +++LL   A    ++     G + L +A    +
Sbjct: 448 RDINVNVMVR-GETTLQQAVRDNYLLGIQVLLRSGANPDLVVRMPSYGQNCLELAVMCRY 624

Query: 330 LNCVQLLLQHN 340
           +N V+ L+ HN
Sbjct: 625 VNAVRALIVHN 657

 Score = 32.7 bits (73), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 29/95 (30%), Positives = 43/95 (45%), Gaps = 1/95 (1%)
 Frame = +1

Query: 189 LHIAARKDDTKAAALLLQNDTNADVESKSGFTPLHIA-AHYGNINVATLLLNRAAAVDFT 247
           LH+A R +D   A  LL+  ++  +   SG TPL +A  H  N  V  +   R   V+  
Sbjct: 292 LHLAVRVNDFHKAKKLLKLGSDPLLPDFSGITPLRMAQGHEYNAIVFYMCYVRDINVNVM 471

Query: 248 ARNDITPLHVASKRGNANMVKLLLDRGAKIDAKTR 282
            R + T L  A +      +++LL  GA  D   R
Sbjct: 472 VRGETT-LQQAVRDNYLLGIQVLLRSGANPDLVVR 573

 Score = 30.0 bits (66), Expect = 8.7,   Method: Compositional matrix adjust.
 Identities = 29/105 (27%), Positives = 47/105 (44%), Gaps = 7/105 (6%)
 Frame = +1

Query: 116 VNAQS-QNGFTPLYMAAQENHLEVVRFLLDNGASQSLATEDGFTPLAVALQQGHDQ---V 171
           +N Q  ++G +PL++A + N     + LL  G+   L    G TPL +A  QGH+    V
Sbjct: 256 LNCQDPRSGQSPLHLAVRVNDFHKAKKLLKLGSDPLLPDFSGITPLRMA--QGHEYNAIV 429

Query: 172 VSLLLENDTKGKVRL---PALHIAARKDDTKAAALLLQNDTNADV 213
             +    D    V +     L  A R +      +LL++  N D+
Sbjct: 430 FYMCYVRDINVNVMVRGETTLQQAVRDNYLLGIQVLLRSGANPDL 564
>05396
          Length = 1865

 Score = 44.3 bits (103), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 29/86 (33%), Positives = 41/86 (47%), Gaps = 1/86 (1%)
 Frame = +3

Query: 486  LHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLAAREGHEDVAAFLLDHG-ASLSIT 544
            L  SA  G    +++    G   +     G T LH+A+ EG   V  FLLD    S  + 
Sbjct: 1296 LLFSAYNGDVTAIRRCALSGMDMSQPDYDGRTALHVASAEGQLQVVEFLLDRCKCSPFLV 1475

Query: 545  TKKGFTPLHVAAKYGKLEVASLLLQK 570
             + GFTPL  A ++ K E A LL ++
Sbjct: 1476 DRWGFTPLDDAVRFEKHEAAELLKER 1553

 Score = 38.1 bits (87), Expect = 0.032,   Method: Compositional matrix adjust.
 Identities = 27/89 (30%), Positives = 40/89 (44%), Gaps = 2/89 (2%)
 Frame = +3

Query: 250  NDITPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDR--S 307
            N I  L  ++  G+   ++     G  +     DG T LH  +  G  QVVE LLDR   
Sbjct: 1281 NRIVDLLFSAYNGDVTAIRRCALSGMDMSQPDYDGRTALHVASAEGQLQVVEFLLDRCKC 1460

Query: 308  APILSKTKNGLSPLHMATQGDHLNCVQLL 336
            +P L   + G +PL  A + +     +LL
Sbjct: 1461 SPFLVD-RWGFTPLDDAVRFEKHEAAELL 1544

 Score = 35.4 bits (80), Expect = 0.21,   Method: Compositional matrix adjust.
 Identities = 23/52 (44%), Positives = 29/52 (55%), Gaps = 1/52 (1%)
 Frame = +3

Query: 352  TALHVAAHCGHYKVAKVLLDK-KASPNAKALNGFTPLHIACKKNRIRVMELL 402
            TALHVA+  G  +V + LLD+ K SP      GFTPL  A +  +    ELL
Sbjct: 1389 TALHVASAEGQLQVVEFLLDRCKCSPFLVDRWGFTPLDDAVRFEKHEAAELL 1544

 Score = 32.7 bits (73), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 24/93 (25%), Positives = 45/93 (48%), Gaps = 5/93 (5%)
 Frame = +3

Query: 417  LTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVE 476
            +  +  +A+ G V  + +    G   +  +  G TALH+A+  GQ +VV +L+ D  +  
Sbjct: 1287 IVDLLFSAYNGDVTAIRRCALSGMDMSQPDYDGRTALHVASAEGQLQVVEFLL-DRCKCS 1463

Query: 477  AKAKDDQ--TPLHISARLGK---ADIVQQLLQQ 504
                D    TPL  + R  K   A+++++ + Q
Sbjct: 1464 PFLVDRWGFTPLDDAVRFEKHEAAELLKERMMQ 1562

 Score = 32.0 bits (71), Expect = 2.2,   Method: Compositional matrix adjust.
 Identities = 15/34 (44%), Positives = 24/34 (70%)
 Frame = +3

Query: 46   NGVDVNICNQNGLNALHLASKEGHVEVVSELLQR 79
            +G+D++  + +G  ALH+AS EG ++VV  LL R
Sbjct: 1350 SGMDMSQPDYDGRTALHVASAEGQLQVVEFLLDR 1451
>25464
          Length = 440

 Score = 44.3 bits (103), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 34/125 (27%), Positives = 55/125 (44%), Gaps = 5/125 (4%)
 Frame = -3

Query: 641 NAVTRQGIASVHLAAQEGHVDMVSLLLSRNA-NVNLSNKSGLTPLHLAAQEDRVNV---- 695
           N     G  ++  A   G  D+V  +L  +  ++N  +  G TP+H AA     N+    
Sbjct: 429 NVRDSMGRTALSYACLNGRQDIVRCILKEDVLDINEPDNDGNTPIHHAAISANPNIVRML 250

Query: 696 AEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTALHQAAQ 755
           AE     G + D + K+GYTPL + C  GN  +  + L  + K +   ++G   L+    
Sbjct: 249 AEAFYKFGLNPDKRNKLGYTPLLLACKGGNY-VSAYTLLTTTKASPTLRDGEFHLNATEW 73

Query: 756 QGHTH 760
              TH
Sbjct: 72  IQRTH 58

 Score = 37.0 bits (84), Expect = 0.070,   Method: Compositional matrix adjust.
 Identities = 29/90 (32%), Positives = 38/90 (42%), Gaps = 5/90 (5%)
 Frame = -3

Query: 377 NAKALNGFTPLHIACKKNRIRVMELLLKHGA-SIQAVTESGLTPIHVAAFMGHVNIVSQL 435
           N +   G T L  AC   R  ++  +LK     I      G TPIH AA   + NIV  L
Sbjct: 429 NVRDSMGRTALSYACLNGRQDIVRCILKEDVLDINEPDNDGNTPIHHAAISANPNIVRML 250

Query: 436 ----MHHGASPNTTNVRGETALHMAARSGQ 461
                  G +P+  N  G T L +A + G 
Sbjct: 249 AEAFYKFGLNPDKRNKLGYTPLLLACKGGN 160

 Score = 30.4 bits (67), Expect = 5.8,   Method: Compositional matrix adjust.
 Identities = 27/98 (27%), Positives = 39/98 (39%), Gaps = 5/98 (5%)
 Frame = -3

Query: 509 NAATTSGYTPLHLAAREGHEDVAAFLLDHGA-SLSITTKKGFTPLHVAAKYGKLEVASLL 567
           N   + G T L  A   G +D+   +L      ++     G TP+H AA      +  +L
Sbjct: 429 NVRDSMGRTALSYACLNGRQDIVRCILKEDVLDINEPDNDGNTPIHHAAISANPNIVRML 250

Query: 568 LQK----SASPDAAGKSGLTPLHVAAHYDNQKVALLLL 601
            +       +PD   K G TPL +A    N   A  LL
Sbjct: 249 AEAFYKFGLNPDKRNKLGYTPLLLACKGGNYVSAYTLL 136
>27108
          Length = 449

 Score = 43.9 bits (102), Expect = 6e-04,   Method: Compositional matrix adjust.
 Identities = 34/107 (31%), Positives = 50/107 (46%), Gaps = 2/107 (1%)
 Frame = -3

Query: 47  GVDVNICNQNGLNALHLASKEGHVEVVSELLQR--EANVDAATKKGNTALHIASLAGQAE 104
           GVD+N  +  G  ALH A   GH+E    LL+    A +D+  + G           + +
Sbjct: 315 GVDINSQDYAGWTALHEACNHGHLECARALLKFVPSATLDSFFQSGKN---------RGK 163

Query: 105 VVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVRFLLDNGASQSL 151
           V KV      +++  +Q G T L+ A   NH+ VV+ LL  G S  L
Sbjct: 162 VRKV------DMHLANQEGITALHDAVSMNHVSVVKLLLKYGGSSLL 40

 Score = 42.4 bits (98), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 42/127 (33%), Positives = 63/127 (49%), Gaps = 7/127 (5%)
 Frame = -3

Query: 336 LLQH--NVP-VDDVTNDY--LTALHVAAHCGHYKVAKVLLDKKASPNAKALNGFTPLHIA 390
           LL+H   VP VD  + DY   TALH A + GH + A+ LL  K  P+A  L+ F      
Sbjct: 342 LLKHLLTVPGVDINSQDYAGWTALHEACNHGHLECARALL--KFVPSA-TLDSF----FQ 184

Query: 391 CKKNRIRVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASP--NTTNVR 448
             KNR +V ++       +    + G+T +H A  M HV++V  L+ +G S       V 
Sbjct: 183 SGKNRGKVRKV------DMHLANQEGITALHDAVSMNHVSVVKLLLKYGGSSLLKDKTVS 22

Query: 449 GETALHM 455
           G+T + +
Sbjct: 21  GDTVMDL 1

 Score = 30.4 bits (67), Expect = 5.9,   Method: Compositional matrix adjust.
 Identities = 26/79 (32%), Positives = 35/79 (44%), Gaps = 20/79 (25%)
 Frame = -3

Query: 548 GFTPLHVAAKYGKLEVASLLLQ--KSASPDA------------------AGKSGLTPLHV 587
           G+T LH A  +G LE A  LL+   SA+ D+                  A + G+T LH 
Sbjct: 285 GWTALHEACNHGHLECARALLKFVPSATLDSFFQSGKNRGKVRKVDMHLANQEGITALHD 106

Query: 588 AAHYDNQKVALLLLDQGAS 606
           A   ++  V  LLL  G S
Sbjct: 105 AVSMNHVSVVKLLLKYGGS 49
>22305
          Length = 426

 Score = 43.5 bits (101), Expect = 7e-04,   Method: Composition-based stats.
 Identities = 25/74 (33%), Positives = 37/74 (50%)
 Frame = -3

Query: 488 ISARLGKADIVQQLLQQGASPNAATTSGYTPLHLAAREGHEDVAAFLLDHGASLSITTKK 547
           +S R+  ADI   LL++G S N     G  PLH A    + +V   LL +GA  ++  + 
Sbjct: 367 VSVRVNAADITTALLERGCSANERNHWGILPLHEALCWENVEVGRVLLQYGADPNVPCET 188

Query: 548 GFTPLHVAAKYGKL 561
              PL  AA+ G +
Sbjct: 187 NVVPLTFAARTGHI 146

 Score = 40.8 bits (94), Expect = 0.004,   Method: Composition-based stats.
 Identities = 28/88 (31%), Positives = 40/88 (45%), Gaps = 10/88 (11%)
 Frame = -3

Query: 512 TTSGYTPLHLAA----------REGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKL 561
           T S Y+ + LAA          R    D+   LL+ G S +     G  PLH A  +  +
Sbjct: 424 THSSYSFMRLAAAPCYTQSVSVRVNAADITTALLERGCSANERNHWGILPLHEALCWENV 245

Query: 562 EVASLLLQKSASPDAAGKSGLTPLHVAA 589
           EV  +LLQ  A P+   ++ + PL  AA
Sbjct: 244 EVGRVLLQYGADPNVPCETNVVPLTFAA 161

 Score = 40.0 bits (92), Expect = 0.008,   Method: Composition-based stats.
 Identities = 27/88 (30%), Positives = 44/88 (50%)
 Frame = -3

Query: 587 VAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATSLLEYGADANAVTRQ 646
           V+   +   +   LL++G S +     G  PLH A     +++   LL+YGAD N     
Sbjct: 367 VSVRVNAADITTALLERGCSANERNHWGILPLHEALCWENVEVGRVLLQYGADPNVPCET 188

Query: 647 GIASVHLAAQEGHVDMVSLLLSRNANVN 674
            +  +  AA+ GH+ +  LLL+  A+VN
Sbjct: 187 NVVPLTFAARTGHIRLAQLLLAAGADVN 104

 Score = 39.3 bits (90), Expect = 0.014,   Method: Composition-based stats.
 Identities = 21/66 (31%), Positives = 33/66 (50%)
 Frame = -3

Query: 103 AEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVRFLLDNGASQSLATEDGFTPLAV 162
           A++   L+  G + N ++  G  PL+ A    ++EV R LL  GA  ++  E    PL  
Sbjct: 346 ADITTALLERGCSANERNHWGILPLHEALCWENVEVGRVLLQYGADPNVPCETNVVPLTF 167

Query: 163 ALQQGH 168
           A + GH
Sbjct: 166 AARTGH 149

 Score = 38.5 bits (88), Expect = 0.025,   Method: Composition-based stats.
 Identities = 21/73 (28%), Positives = 33/73 (45%)
 Frame = -3

Query: 455 MAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTS 514
           ++ R   A++   L++ G     +      PLH +      ++ + LLQ GA PN    +
Sbjct: 367 VSVRVNAADITTALLERGCSANERNHWGILPLHEALCWENVEVGRVLLQYGADPNVPCET 188

Query: 515 GYTPLHLAAREGH 527
              PL  AAR GH
Sbjct: 187 NVVPLTFAARTGH 149

 Score = 37.4 bits (85), Expect = 0.052,   Method: Composition-based stats.
 Identities = 22/79 (27%), Positives = 37/79 (46%), Gaps = 3/79 (3%)
 Frame = -3

Query: 683 PLHLAAQEDRVNVAEV---LVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKV 739
           P +  +   RVN A++   L+ +G   + +   G  PLH    + N+++   LLQ+ A  
Sbjct: 385 PCYTQSVSVRVNAADITTALLERGCSANERNHWGILPLHEALCWENVEVGRVLLQYGADP 206

Query: 740 NAKTKNGYTALHQAAQQGH 758
           N   +     L  AA+ GH
Sbjct: 205 NVPCETNVVPLTFAARTGH 149

 Score = 34.3 bits (77), Expect = 0.42,   Method: Composition-based stats.
 Identities = 20/73 (27%), Positives = 32/73 (43%)
 Frame = -3

Query: 389 IACKKNRIRVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVR 448
           ++ + N   +   LL+ G S       G+ P+H A    +V +   L+ +GA PN     
Sbjct: 367 VSVRVNAADITTALLERGCSANERNHWGILPLHEALCWENVEVGRVLLQYGADPNVPCET 188

Query: 449 GETALHMAARSGQ 461
               L  AAR+G 
Sbjct: 187 NVVPLTFAARTGH 149

 Score = 30.0 bits (66), Expect = 8.0,   Method: Composition-based stats.
 Identities = 20/65 (30%), Positives = 26/65 (40%)
 Frame = -3

Query: 728 IVNFLLQHSAKVNAKTKNGYTALHQAAQQGHTHIINVLLQNNASPNELTVNGNTALAIAR 787
           I   LL+     N +   G   LH+A    +  +  VLLQ  A PN         L  A 
Sbjct: 340 ITTALLERGCSANERNHWGILPLHEALCWENVEVGRVLLQYGADPNVPCETNVVPLTFAA 161

Query: 788 RLGYI 792
           R G+I
Sbjct: 160 RTGHI 146
>20121
          Length = 454

 Score = 43.5 bits (101), Expect = 8e-04,   Method: Compositional matrix adjust.
 Identities = 29/103 (28%), Positives = 47/103 (45%), Gaps = 3/103 (2%)
 Frame = -1

Query: 371 DKKASPNAKALNGFTPLHIACKKNRIRVMELLL---KHGASIQAVTESGLTPIHVAAFMG 427
           D   +  +K L    P+H     N  R ++ LL   +H   I+     G T +H++  +G
Sbjct: 388 DSTTTMASKTLQEEFPIHWLTWHNNFRELDRLLGLKEH--DIETKDPRGRTALHLSVSLG 215

Query: 428 HVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQ 470
           H+     L+ HGA   T N    + LH    SG  E+V+ ++Q
Sbjct: 214 HLESTRVLLRHGAEAGTENNGCWSVLHEGVCSGDPELVQLILQ 86

 Score = 36.6 bits (83), Expect = 0.096,   Method: Composition-based stats.
 Identities = 21/112 (18%), Positives = 52/112 (46%), Gaps = 3/112 (2%)
 Frame = -1

Query: 659 HVDMVSLLLSRNANVNLSNKSGLT--PLHLAAQEDRVNVAEVLVNQGAH-VDAQTKMGYT 715
           H D++ ++   ++   +++K+     P+H     +     + L+    H ++ +   G T
Sbjct: 421 HSDVILVVFC*DSTTTMASKTLQEEFPIHWLTWHNNFRELDRLLGLKEHDIETKDPRGRT 242

Query: 716 PLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTALHQAAQQGHTHIINVLLQ 767
            LH+    G+++    LL+H A+   +    ++ LH+    G   ++ ++LQ
Sbjct: 241 ALHLSVSLGHLESTRVLLRHGAEAGTENNGCWSVLHEGVCSGDPELVQLILQ 86

 Score = 33.1 bits (74), Expect = 1.1,   Method: Composition-based stats.
 Identities = 19/55 (34%), Positives = 25/55 (45%)
 Frame = -1

Query: 515 GYTPLHLAAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVASLLLQ 569
           G T LHL+   GH +    LL HGA         ++ LH     G  E+  L+LQ
Sbjct: 250 GRTALHLSVSLGHLESTRVLLRHGAEAGTENNGCWSVLHEGVCSGDPELVQLILQ 86

 Score = 30.8 bits (68), Expect = 5.3,   Method: Composition-based stats.
 Identities = 27/115 (23%), Positives = 52/115 (45%), Gaps = 5/115 (4%)
 Frame = -1

Query: 296 HEQVVEMLL--DRSAPILSKTKNGLSPLHMATQGDHLNCVQLLL---QHNVPVDDVTNDY 350
           H  V+ ++   D +  + SKT     P+H  T  ++   +  LL   +H++   D     
Sbjct: 421 HSDVILVVFC*DSTTTMASKTLQEEFPIHWLTWHNNFRELDRLLGLKEHDIETKDPRGR- 245

Query: 351 LTALHVAAHCGHYKVAKVLLDKKASPNAKALNGFTPLHIACKKNRIRVMELLLKH 405
            TALH++   GH +  +VLL   A    +    ++ LH         +++L+L++
Sbjct: 244 -TALHLSVSLGHLESTRVLLRHGAEAGTENNGCWSVLHEGVCSGDPELVQLILQY 83

 Score = 30.0 bits (66), Expect = 8.0,   Method: Composition-based stats.
 Identities = 17/62 (27%), Positives = 29/62 (46%)
 Frame = -1

Query: 49  DVNICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQAEVVKV 108
           D+   +  G  ALHL+   GH+E    LL+  A          + LH    +G  E+V++
Sbjct: 274 DIETKDPRGRTALHLSVSLGHLESTRVLLRHGAEAGTENNGCWSVLHEGVCSGDPELVQL 95

Query: 109 LV 110
           ++
Sbjct: 94  IL 89
>30217
          Length = 412

 Score = 43.1 bits (100), Expect = 0.001,   Method: Composition-based stats.
 Identities = 22/64 (34%), Positives = 37/64 (57%), Gaps = 3/64 (4%)
 Frame = -3

Query: 414 ESGLTPIHVAAFMGHVNIVSQLMHHGASP---NTTNVRGETALHMAARSGQAEVVRYLVQ 470
           + G TP+H+A   G+V++V+ L+     P   N  N   +T LH+AA + Q  ++R L+ 
Sbjct: 212 DDGDTPLHLACISGYVDVVAALIRMAPHPCLLNIQNDVAQTPLHLAALTAQPTILRMLLL 33

Query: 471 DGAQ 474
            GA+
Sbjct: 32  AGAE 21

 Score = 39.3 bits (90), Expect = 0.015,   Method: Composition-based stats.
 Identities = 31/93 (33%), Positives = 41/93 (44%), Gaps = 3/93 (3%)
 Frame = -3

Query: 485 PLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLAAREGHEDVAAFLL---DHGASL 541
           PL  S  +   +  +Q  QQ          G TPLHLA   G+ DV A L+    H   L
Sbjct: 275 PLSGSNNINIMNAWEQFYQQ-------NDDGDTPLHLACISGYVDVVAALIRMAPHPCLL 117

Query: 542 SITTKKGFTPLHVAAKYGKLEVASLLLQKSASP 574
           +I      TPLH+AA   +  +  +LL   A P
Sbjct: 116 NIQNDVAQTPLHLAALTAQPTILRMLLLAGAEP 18

 Score = 37.0 bits (84), Expect = 0.069,   Method: Composition-based stats.
 Identities = 20/68 (29%), Positives = 33/68 (48%), Gaps = 3/68 (4%)
 Frame = -3

Query: 382 NGFTPLHIACKKNRIRVMELLLK---HGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHH 438
           +G TPLH+AC    + V+  L++   H   +    +   TP+H+AA      I+  L+  
Sbjct: 209 DGDTPLHLACISGYVDVVAALIRMAPHPCLLNIQNDVAQTPLHLAALTAQPTILRMLLLA 30

Query: 439 GASPNTTN 446
           GA P   +
Sbjct: 29  GAEPTVRD 6

 Score = 36.6 bits (83), Expect = 0.084,   Method: Composition-based stats.
 Identities = 23/73 (31%), Positives = 32/73 (43%), Gaps = 3/73 (4%)
 Frame = -3

Query: 474 QVEAKAKDDQTPLHISARLGKADIVQQLLQQGASP---NAATTSGYTPLHLAAREGHEDV 530
           Q   +  D  TPLH++   G  D+V  L++    P   N       TPLHLAA      +
Sbjct: 230 QFYQQNDDGDTPLHLACISGYVDVVAALIRMAPHPCLLNIQNDVAQTPLHLAALTAQPTI 51

Query: 531 AAFLLDHGASLSI 543
              LL  GA  ++
Sbjct: 50  LRMLLLAGAEPTV 12

 Score = 34.7 bits (78), Expect = 0.39,   Method: Composition-based stats.
 Identities = 22/72 (30%), Positives = 38/72 (52%), Gaps = 3/72 (4%)
 Frame = -3

Query: 214 ESKSGFTPLHIAAHYGNINVATLLLNRAA-AVDFTARNDI--TPLHVASKRGNANMVKLL 270
           ++  G TPLH+A   G ++V   L+  A        +ND+  TPLH+A+      ++++L
Sbjct: 218 QNDDGDTPLHLACISGYVDVVAALIRMAPHPCLLNIQNDVAQTPLHLAALTAQPTILRML 39

Query: 271 LDRGAKIDAKTR 282
           L  GA+   + R
Sbjct: 38  LLAGAEPTVRDR 3

 Score = 33.9 bits (76), Expect = 0.59,   Method: Composition-based stats.
 Identities = 25/90 (27%), Positives = 38/90 (42%), Gaps = 12/90 (13%)
 Frame = -3

Query: 667 LSRNANVNL---------SNKSGLTPLHLAAQEDRVNVAEVLVNQGAH---VDAQTKMGY 714
           LS + N+N+          N  G TPLHLA     V+V   L+    H   ++ Q  +  
Sbjct: 272 LSGSNNINIMNAWEQFYQQNDDGDTPLHLACISGYVDVVAALIRMAPHPCLLNIQNDVAQ 93

Query: 715 TPLHVGCHYGNIKIVNFLLQHSAKVNAKTK 744
           TPLH+        I+  LL   A+   + +
Sbjct: 92  TPLHLAALTAQPTILRMLLLAGAEPTVRDR 3

 Score = 33.5 bits (75), Expect = 0.70,   Method: Composition-based stats.
 Identities = 21/63 (33%), Positives = 32/63 (50%), Gaps = 3/63 (4%)
 Frame = -3

Query: 548 GFTPLHVAAKYGKLEVASLLLQKSASP---DAAGKSGLTPLHVAAHYDNQKVALLLLDQG 604
           G TPLH+A   G ++V + L++ +  P   +       TPLH+AA      +  +LL  G
Sbjct: 206 GDTPLHLACISGYVDVVAALIRMAPHPCLLNIQNDVAQTPLHLAALTAQPTILRMLLLAG 27

Query: 605 ASP 607
           A P
Sbjct: 26  AEP 18
>03590
          Length = 1068

 Score = 32.7 bits (73), Expect(2) = 0.001,   Method: Compositional matrix adjust.
 Identities = 33/122 (27%), Positives = 60/122 (49%), Gaps = 13/122 (10%)
 Frame = +1

Query: 236 LLLNRAAAVDFTARNDITPLHVASKRGNANMVKLLLDRGAKIDAKTRDGL-----TPLHC 290
           L+L     ++    N  TPL +A++  +A+ VKLL + GA +DA  +  L     TP   
Sbjct: 391 LILRYKPDLECQTLNSDTPLVLAARSQSADKVKLLAEMGANVDALIKSKLNGNHVTPCLW 570

Query: 291 GARSGHEQVVEMLLDRSA---PILSKTKNGLSPLHM-----ATQGDHLNCVQLLLQHNVP 342
            A   +  +V++LL   A    + + TK  L  +H      + +GD +  ++LL++  + 
Sbjct: 571 MAMQKNLPLVKLLLKYGADPKAVSAYTKETL--MHCLVRDRSAEGDVIQLLKLLVEKGLS 744

Query: 343 VD 344
           V+
Sbjct: 745 VN 750

 Score = 29.3 bits (64), Expect(2) = 0.001,   Method: Compositional matrix adjust.
 Identities = 28/98 (28%), Positives = 40/98 (40%), Gaps = 12/98 (12%)
 Frame = +3

Query: 385 TPLHIACKKNR------IRVMELLLKHGASIQAVTESGLTPIHVAAFMGH----VNIVSQ 434
           T LH A   NR        + E LL+H A + A  + G  PIH   F+G     + ++S 
Sbjct: 771 TVLHTAVSNNRGDANDSTALEEFLLEHKADVFAKNDDGYMPIHC-VFVGCGPDPIELLSL 947

Query: 435 LMHHGASPNTTN--VRGETALHMAARSGQAEVVRYLVQ 470
           L             + G + LH AA  G      +L+Q
Sbjct: 948 LTAAMKDQQVDEPVLSGFSPLHFAAARGATICCMHLLQ 1061

 Score = 41.6 bits (96), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 33/103 (32%), Positives = 50/103 (48%), Gaps = 14/103 (13%)
 Frame = +3

Query: 248 ARNDITPLHVASKRGNAN----MVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEML 303
           AR+ +    V++ RG+AN    + + LL+  A + AK  DG  P+HC         +E+L
Sbjct: 762 ARDTVLHTAVSNNRGDANDSTALEEFLLEHKADVFAKNDDGYMPIHCVFVGCGPDPIELL 941

Query: 304 LDRSA---------PILSKTKNGLSPLHM-ATQGDHLNCVQLL 336
              +A         P+LS    G SPLH  A +G  + C+ LL
Sbjct: 942 SLLTAAMKDQQVDEPVLS----GFSPLHFAAARGATICCMHLL 1058

 Score = 34.3 bits (77), Expect = 0.41,   Method: Compositional matrix adjust.
 Identities = 41/159 (25%), Positives = 72/159 (45%), Gaps = 19/159 (11%)
 Frame = +1

Query: 634 LEYGADANAVTRQGIASVH--LAAQEGHVDM----VSLLLSRNANVNLSNKSGLTPLHLA 687
           L Y A+        +AS    +  +EG V+     ++L+L    ++     +  TPL LA
Sbjct: 280 LSYTAEGKYTATHLMASCQTEMPVKEGGVEEKHPGLALILRYKPDLECQTLNSDTPLVLA 459

Query: 688 AQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVG-CHY----GNIKIVNFLLQHSAK---V 739
           A+    +  ++L   GA+VDA  K      HV  C +     N+ +V  LL++ A    V
Sbjct: 460 ARSQSADKVKLLAEMGANVDALIKSKLNGNHVTPCLWMAMQKNLPLVKLLLKYGADPKAV 639

Query: 740 NAKTKNGYTALH-----QAAQQGHTHIINVLLQNNASPN 773
           +A TK   T +H     ++A+     ++ +L++   S N
Sbjct: 640 SAYTKE--TLMHCLVRDRSAEGDVIQLLKLLVEKGLSVN 750

 Score = 31.6 bits (70), Expect = 2.9,   Method: Compositional matrix adjust.
 Identities = 35/127 (27%), Positives = 53/127 (41%), Gaps = 13/127 (10%)
 Frame = +1

Query: 633 LLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLSRNANVNLSNKSGL-----TPLHLA 687
           +L Y  D    T      + LAA+    D V LL    ANV+   KS L     TP    
Sbjct: 394 ILRYKPDLECQTLNSDTPLVLAARSQSADKVKLLAEMGANVDALIKSKLNGNHVTPCLWM 573

Query: 688 AQEDRVNVAEVLVNQGAH---VDAQTKMGYTPLHV-----GCHYGNIKIVNFLLQHSAKV 739
           A +  + + ++L+  GA    V A TK   T +H            I+++  L++    V
Sbjct: 574 AMQKNLPLVKLLLKYGADPKAVSAYTK--ETLMHCLVRDRSAEGDVIQLLKLLVEKGLSV 747

Query: 740 NAKTKNG 746
           N++ K G
Sbjct: 748 NSRDKRG 768

 Score = 30.8 bits (68), Expect = 5.2,   Method: Compositional matrix adjust.
 Identities = 32/109 (29%), Positives = 48/109 (44%), Gaps = 11/109 (10%)
 Frame = +1

Query: 517 TPLHLAAREGHEDVAAFLLDHGASLSITTKKGF-----TPLHVAAKYGKLEVASLLLQKS 571
           TPL LAAR    D    L + GA++    K        TP    A    L +  LLL+  
Sbjct: 442 TPLVLAARSQSADKVKLLAEMGANVDALIKSKLNGNHVTPCLWMAMQKNLPLVKLLLKYG 621

Query: 572 ASPDA-AGKSGLTPLHV-----AAHYDNQKVALLLLDQGASPHAAAKNG 614
           A P A +  +  T +H      +A  D  ++  LL+++G S ++  K G
Sbjct: 622 ADPKAVSAYTKETLMHCLVRDRSAEGDVIQLLKLLVEKGLSVNSRDKRG 768
>36879
          Length = 583

 Score = 42.7 bits (99), Expect = 0.001,   Method: Composition-based stats.
 Identities = 28/70 (40%), Positives = 37/70 (52%), Gaps = 7/70 (10%)
 Frame = -3

Query: 585 LHVAAHYD------NQKVALLLLD-QGASPHAAAKNGYTPLHIAAKKNQMDIATSLLEYG 637
           ++   H+D      N  V LLL+D +G + HA    G TPL +AAK  Q  +   LLE G
Sbjct: 572 IYCRKHFDHDDDFINMYVDLLLMDCEGINIHAIDDVGETPLMLAAKNGQDYVCERLLEAG 393

Query: 638 ADANAVTRQG 647
           AD  A+  QG
Sbjct: 392 ADPLAIXLQG 363
>08755
          Length = 885

 Score = 39.7 bits (91), Expect = 0.011,   Method: Compositional matrix adjust.
 Identities = 23/73 (31%), Positives = 42/73 (57%), Gaps = 1/73 (1%)
 Frame = +3

Query: 647 GIASVHLAAQEGHVDMVSLLLSRNANVNLS-NKSGLTPLHLAAQEDRVNVAEVLVNQGAH 705
           G +++H+A +   V  +S+LL+  AN ++  + SG+TPL LAA   +    ++L+  G+ 
Sbjct: 654 GQSALHIAVKNPEV--ISVLLAHGANPDVKVDGSGVTPLMLAASMTKTAALQILIGAGSS 827

Query: 706 VDAQTKMGYTPLH 718
           +D +   G   LH
Sbjct: 828 IDCRNNAGMCALH 866

 Score = 38.1 bits (87), Expect = 0.030,   Method: Compositional matrix adjust.
 Identities = 25/79 (31%), Positives = 36/79 (45%), Gaps = 1/79 (1%)
 Frame = +3

Query: 481 DDQTPLHISARLGKADIVQQLLQQGASPNAATT-SGYTPLHLAAREGHEDVAAFLLDHGA 539
           D Q+ LHI+ +    +++  LL  GA+P+     SG TPL LAA          L+  G+
Sbjct: 651 DGQSALHIAVK--NPEVISVLLAHGANPDVKVDGSGVTPLMLAASMTKTAALQILIGAGS 824

Query: 540 SLSITTKKGFTPLHVAAKY 558
           S+      G   LH    Y
Sbjct: 825 SIDCRNNAGMCALHHCFSY 881

 Score = 36.2 bits (82), Expect = 0.13,   Method: Compositional matrix adjust.
 Identities = 28/74 (37%), Positives = 40/74 (54%), Gaps = 1/74 (1%)
 Frame = +3

Query: 382 NGFTPLHIACKKNRIRVMELLLKHGASIQA-VTESGLTPIHVAAFMGHVNIVSQLMHHGA 440
           +G + LHIA K     V+ +LL HGA+    V  SG+TP+ +AA M     +  L+  G+
Sbjct: 651 DGQSALHIAVKNPE--VISVLLAHGANPDVKVDGSGVTPLMLAASMTKTAALQILIGAGS 824

Query: 441 SPNTTNVRGETALH 454
           S +  N  G  ALH
Sbjct: 825 SIDCRNNAGMCALH 866
>04513
          Length = 434

 Score = 38.5 bits (88), Expect = 0.027,   Method: Compositional matrix adjust.
 Identities = 25/64 (39%), Positives = 37/64 (57%), Gaps = 5/64 (7%)
 Frame = -2

Query: 258 ASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHE-QVVEMLLDRSA----PILS 312
           ASK G+ + V++LLD+G +++A  +  LTPL     S  +  VV +L+D  A    P L 
Sbjct: 433 ASKYGDKDTVQVLLDKGGQVNAVGKYKLTPLMWACCSRDDVAVVNLLIDHHALSS*PTLK 254

Query: 313 KTKN 316
           KT N
Sbjct: 253 KTVN 242

 Score = 33.1 bits (74), Expect = 0.96,   Method: Composition-based stats.
 Identities = 21/52 (40%), Positives = 27/52 (51%), Gaps = 1/52 (1%)
 Frame = -2

Query: 555 AAKYGKLEVASLLLQKSASPDAAGKSGLTPLHVA-AHYDNQKVALLLLDQGA 605
           A+KYG  +   +LL K    +A GK  LTPL  A    D+  V  LL+D  A
Sbjct: 433 ASKYGDKDTVQVLLDKGGQVNAVGKYKLTPLMWACCSRDDVAVVNLLIDHHA 278

 Score = 31.6 bits (70), Expect = 3.2,   Method: Composition-based stats.
 Identities = 20/55 (36%), Positives = 28/55 (50%), Gaps = 1/55 (1%)
 Frame = -2

Query: 97  ASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMA-AQENHLEVVRFLLDNGASQS 150
           AS  G  + V+VL+  G  VNA  +   TPL  A    + + VV  L+D+ A  S
Sbjct: 433 ASKYGDKDTVQVLLDKGGQVNAVGKYKLTPLMWACCSRDDVAVVNLLIDHHALSS 269
>09214
          Length = 2116

 Score = 37.4 bits (85), Expect = 0.059,   Method: Compositional matrix adjust.
 Identities = 26/75 (34%), Positives = 36/75 (48%)
 Frame = -3

Query: 613  NGYTPLHIAAKKNQMDIATSLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLSRNAN 672
            NG T LH  AK++   +   LL +GAD NAV   G     +A Q      V  LL  + +
Sbjct: 1613 NGRTALHWGAKRDHQTVVQYLLSHGADKNAVDNDG----KIAGQLTTNSDVHTLLGGSGD 1446

Query: 673  VNLSNKSGLTPLHLA 687
            V    +  +TP +LA
Sbjct: 1445 VTNQEQLPITPSYLA 1401

 Score = 33.1 bits (74), Expect = 0.91,   Method: Compositional matrix adjust.
 Identities = 23/61 (37%), Positives = 33/61 (54%), Gaps = 4/61 (6%)
 Frame = -3

Query: 360  CGHY--KVAKVLLD-KKASPNAK-ALNGFTPLHIACKKNRIRVMELLLKHGASIQAVTES 415
            C ++   VAK L++ K    NA+  +NG T LH   K++   V++ LL HGA   AV   
Sbjct: 1691 CQYW*HGVAKKLVEVKNVDVNAQNKMNGRTALHWGAKRDHQTVVQYLLSHGADKNAVDND 1512

Query: 416  G 416
            G
Sbjct: 1511 G 1509
>20757
          Length = 1062

 Score = 37.0 bits (84), Expect = 0.067,   Method: Compositional matrix adjust.
 Identities = 28/83 (33%), Positives = 37/83 (44%), Gaps = 1/83 (1%)
 Frame = -1

Query: 1434 SPCERTDIRMAIVADHLGLSWTELARELNFSVDEINQIRVENP-NSLISQSFMLLKKWVT 1492
            S  E T   M IV+  +   W  L REL  S   + QIR++N  +     ++ +LKKW  
Sbjct: 561  SQAEPTHDHMDIVSREISGDWQRLGRELKLSDAXLEQIRLDNHLHGAYEINYQMLKKWKE 382

Query: 1493 RDGKNATTDALTSVLTKINRIDI 1515
                  T  AL   L  I R DI
Sbjct: 381  ISAP-VTVHALALALATIVRGDI 316
>18216
          Length = 472

 Score = 36.6 bits (83), Expect = 0.092,   Method: Composition-based stats.
 Identities = 25/63 (39%), Positives = 32/63 (50%)
 Frame = +2

Query: 94  LHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVRFLLDNGASQSLAT 153
           L +A + GQ     VL   G +VNA    G+T    AA E HL VV+ LL+ GA  S+  
Sbjct: 221 LRLAQIXGQGGCEGVL-DKGVHVNAVDPFGWTAAMSAAFEGHLAVVQTLLEAGADLSVIN 397

Query: 154 EDG 156
             G
Sbjct: 398 RQG 406

 Score = 34.7 bits (78), Expect = 0.38,   Method: Composition-based stats.
 Identities = 19/50 (38%), Positives = 27/50 (54%)
 Frame = +2

Query: 499 QQLLQQGASPNAATTSGYTPLHLAAREGHEDVAAFLLDHGASLSITTKKG 548
           + +L +G   NA    G+T    AA EGH  V   LL+ GA LS+  ++G
Sbjct: 257 EGVLDKGVHVNAVDPFGWTAAMSAAFEGHLAVVQTLLEAGADLSVINRQG 406

 Score = 33.9 bits (76), Expect = 0.57,   Method: Composition-based stats.
 Identities = 17/48 (35%), Positives = 27/48 (56%)
 Frame = +2

Query: 600 LLDQGASPHAAAKNGYTPLHIAAKKNQMDIATSLLEYGADANAVTRQG 647
           +LD+G   +A    G+T    AA +  + +  +LLE GAD + + RQG
Sbjct: 263 VLDKGVHVNAVDPFGWTAAMSAAFEGHLAVVQTLLEAGADLSVINRQG 406

 Score = 32.3 bits (72), Expect = 1.6,   Method: Composition-based stats.
 Identities = 18/50 (36%), Positives = 25/50 (50%)
 Frame = +2

Query: 400 ELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRG 449
           E +L  G  + AV   G T    AAF GH+ +V  L+  GA  +  N +G
Sbjct: 257 EGVLDKGVHVNAVDPFGWTAAMSAAFEGHLAVVQTLLEAGADLSVINRQG 406

 Score = 31.2 bits (69), Expect = 4.2,   Method: Composition-based stats.
 Identities = 17/48 (35%), Positives = 27/48 (56%)
 Frame = +2

Query: 633 LLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLSRNANVNLSNKSG 680
           +L+ G   NAV   G  +   AA EGH+ +V  LL   A++++ N+ G
Sbjct: 263 VLDKGVHVNAVDPFGWTAAMSAAFEGHLAVVQTLLEAGADLSVINRQG 406
>02351
          Length = 939

 Score = 36.2 bits (82), Expect = 0.10,   Method: Compositional matrix adjust.
 Identities = 21/59 (35%), Positives = 28/59 (47%)
 Frame = +3

Query: 56  NGLNALHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQAEVVKVLVTNGA 114
           +G  ALH+A+  G+V  V  LL   ANV     +G  AL  A  +G  E   +L   G 
Sbjct: 465 DGRTALHIAAALGNVVYVQLLLWYCANVKVVDHEGRNALWYARTSGSVECTDLLAAAGC 641

 Score = 34.7 bits (78), Expect = 0.32,   Method: Compositional matrix adjust.
 Identities = 26/100 (26%), Positives = 40/100 (40%)
 Frame = +3

Query: 48  VDVNICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQAEVVK 107
           +D+ I NQ  ++AL        + ++      + N       G TALHIA+  G    V+
Sbjct: 345 IDIPI-NQQLIDALVREDIRNIIIILGHAASDDINSPYGKDDGRTALHIAAALGNVVYVQ 521

Query: 108 VLVTNGANVNAQSQNGFTPLYMAAQENHLEVVRFLLDNGA 147
           +L+   ANV      G   L+ A     +E    L   G 
Sbjct: 522 LLLWYCANVKVVDHEGRNALWYARTSGSVECTDLLAAAGC 641

 Score = 32.0 bits (71), Expect = 2.2,   Method: Compositional matrix adjust.
 Identities = 17/53 (32%), Positives = 22/53 (41%)
 Frame = +3

Query: 713 GYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTALHQAAQQGHTHIINVL 765
           G T LH+    GN+  V  LL + A V      G  AL  A   G     ++L
Sbjct: 468 GRTALHIAAALGNVVYVQLLLWYCANVKVVDHEGRNALWYARTSGSVECTDLL 626

 Score = 31.2 bits (69), Expect = 4.0,   Method: Compositional matrix adjust.
 Identities = 24/85 (28%), Positives = 33/85 (38%), Gaps = 4/85 (4%)
 Frame = +3

Query: 195 KDDTKAAALLL----QNDTNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFTARN 250
           ++D +   ++L     +D N+      G T LHIAA  GN+    LLL   A V      
Sbjct: 387 REDIRNIIIILGHAASDDINSPYGKDDGRTALHIAAALGNVVYVQLLLWYCANVKVVDHE 566

Query: 251 DITPLHVASKRGNANMVKLLLDRGA 275
               L  A   G+     LL   G 
Sbjct: 567 GRNALWYARTSGSVECTDLLAAAGC 641
>37115
          Length = 114

 Score = 36.2 bits (82), Expect = 0.13,   Method: Compositional matrix adjust.
 Identities = 14/32 (43%), Positives = 22/32 (68%)
 Frame = -1

Query: 376 PNAKALNGFTPLHIACKKNRIRVMELLLKHGA 407
           P+ ++L G T + IA  +   R++ELL+KHGA
Sbjct: 102 PDVRSLTGLTSVEIAAAQGSTRLLELLVKHGA 7
>33484
          Length = 436

 Score = 35.0 bits (79), Expect = 0.24,   Method: Compositional matrix adjust.
 Identities = 21/70 (30%), Positives = 36/70 (51%), Gaps = 1/70 (1%)
 Frame = -2

Query: 337 LQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKASPNAKALNG-FTPLHIACKKNR 395
           L  +  V D T +  + L +A   G+Y++A+VLL   A+   + + G  TPL  A     
Sbjct: 216 LYESGSVPDTTEEGESLLSLACSAGYYELAQVLLAMNANVEDRGIKGDCTPLMEAASGGF 37

Query: 396 IRVMELLLKH 405
           + ++ LL+ H
Sbjct: 36  VDIVRLLILH 7
>36917
          Length = 443

 Score = 33.1 bits (74), Expect = 0.90,   Method: Compositional matrix adjust.
 Identities = 16/37 (43%), Positives = 23/37 (62%)
 Frame = -1

Query: 519 LHLAAREGHEDVAAFLLDHGASLSITTKKGFTPLHVA 555
           LH+AA  G+ +VA FLLD+  S+     + + PLH A
Sbjct: 113 LHIAAANGYIEVAEFLLDNHVSVDRQDHESWQPLHAA 3

 Score = 32.3 bits (72), Expect = 1.7,   Method: Compositional matrix adjust.
 Identities = 16/37 (43%), Positives = 18/37 (48%)
 Frame = -1

Query: 552 LHVAAKYGKLEVASLLLQKSASPDAAGKSGLTPLHVA 588
           LH+AA  G +EVA  LL    S D        PLH A
Sbjct: 113 LHIAAANGYIEVAEFLLDNHVSVDRQDHESWQPLHAA 3

 Score = 30.0 bits (66), Expect = 7.5,   Method: Compositional matrix adjust.
 Identities = 17/37 (45%), Positives = 19/37 (51%)
 Frame = -1

Query: 222 LHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVA 258
           LHIAA  G I VA  LL+   +VD        PLH A
Sbjct: 113 LHIAAANGYIEVAEFLLDNHVSVDRQDHESWQPLHAA 3

 Score = 30.0 bits (66), Expect = 7.5,   Method: Compositional matrix adjust.
 Identities = 15/37 (40%), Positives = 22/37 (59%)
 Frame = -1

Query: 354 LHVAAHCGHYKVAKVLLDKKASPNAKALNGFTPLHIA 390
           LH+AA  G+ +VA+ LLD   S + +    + PLH A
Sbjct: 113 LHIAAANGYIEVAEFLLDNHVSVDRQDHESWQPLHAA 3
>35959
          Length = 383

 Score = 32.7 bits (73), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 21/54 (38%), Positives = 29/54 (53%), Gaps = 4/54 (7%)
 Frame = -3

Query: 356 VAAHCGH----YKVAKVLLDKKASPNAKALNGFTPLHIACKKNRIRVMELLLKH 405
           + AH GH    ++   +   K ASPN K   G+TPL  A K N I ++ LLL +
Sbjct: 174 LPAHPGHPPLQHRPGSLPPQKGASPNFKDSMGYTPLIHAVKMNDITMVRLLLDY 13

 Score = 30.8 bits (68), Expect = 5.0,   Method: Compositional matrix adjust.
 Identities = 14/32 (43%), Positives = 20/32 (62%)
 Frame = -3

Query: 113 GANVNAQSQNGFTPLYMAAQENHLEVVRFLLD 144
           GA+ N +   G+TPL  A + N + +VR LLD
Sbjct: 111 GASPNFKDSMGYTPLIHAVKMNDITMVRLLLD 16
>28671
          Length = 1156

 Score = 32.0 bits (71), Expect = 2.1,   Method: Compositional matrix adjust.
 Identities = 41/155 (26%), Positives = 68/155 (43%), Gaps = 12/155 (7%)
 Frame = +2

Query: 294 SGHEQVVEMLLDRSAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTA 353
           SG +  VE + D S   +    N ++P  ++  G+ L  V  LL H   V   T+D L A
Sbjct: 8   SGGKTCVEQV-DCSTLHVEDVYNQVNPHELSAWGERL--VDFLLDHQACVGKKTSDPL-A 175

Query: 354 LHVAAHCGHYKVAKVLLDKKASPNAKALN-------GFTPLHIACKKNRIRVM-----EL 401
           +H+      +  A  L     +    +LN       G T LH+  K+  + ++      L
Sbjct: 176 VHLVKLAFKHATAGALRWVLKNRTIDSLNLDSADMKGDTTLHLIAKQRPLSLIHQVMVRL 355

Query: 402 LLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLM 436
           LL++GA    V  +G TP      +G  N+V +++
Sbjct: 356 LLQNGALPNXVDRAGKTPSQYLLDIGSSNVVVRMI 460

 Score = 30.4 bits (67), Expect = 6.2,   Method: Compositional matrix adjust.
 Identities = 25/73 (34%), Positives = 37/73 (50%), Gaps = 6/73 (8%)
 Frame = +2

Query: 82  NVDAATKKGNTALHIA------SLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENH 135
           N+D+A  KG+T LH+       SL  Q  +V++L+ NGA  N   + G TP         
Sbjct: 260 NLDSADMKGDTTLHLIAKQRPLSLIHQV-MVRLLLQNGALPNXVDRAGKTP--------- 409

Query: 136 LEVVRFLLDNGAS 148
               ++LLD G+S
Sbjct: 410 ---SQYLLDIGSS 439
>20955
          Length = 1122

 Score = 32.0 bits (71), Expect = 2.4,   Method: Compositional matrix adjust.
 Identities = 21/68 (30%), Positives = 36/68 (52%), Gaps = 5/68 (7%)
 Frame = +2

Query: 115 NVNAQSQNGFTPLYMAAQENHLEV----VRFLLDNGASQSLATEDGFTPLAVALQQGHDQ 170
            VNA    GFT L++A Q+ + +V    +RFL+ +GA   +   +  T +   + +G  Q
Sbjct: 44  QVNAVDDRGFTLLHLATQDWNRDVGLSNIRFLMHHGADPGVKDSNSMTVIQSLVGKGDTQ 223

Query: 171 V-VSLLLE 177
             V +L+E
Sbjct: 224 CDVDMLVE 247
>07652
          Length = 848

 Score = 30.8 bits (68), Expect = 4.6,   Method: Composition-based stats.
 Identities = 13/26 (50%), Positives = 18/26 (69%)
 Frame = -3

Query: 926 SWAADTLDNVNLVSSPVHSGFLVSFM 951
           SW+  T  N+NLVS+PV SG L  ++
Sbjct: 735 SWSP*TXKNINLVSNPVQSGALYMYI 658
>28491
          Length = 394

 Score = 30.4 bits (67), Expect = 6.3,   Method: Compositional matrix adjust.
 Identities = 22/79 (27%), Positives = 41/79 (51%), Gaps = 5/79 (6%)
 Frame = +3

Query: 222 LHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRGNAN----MVKLLLDRGAKI 277
           L  A  +  ++  + LL+ A +++    +  TPL  AS+    +    ++KLLL +G+ +
Sbjct: 111 LFTAIAFHKLHKLSALLSEARSMEIRNEHSCTPLLYASRYAKGDHGIYLIKLLLRQGSDV 290

Query: 278 DAKTRDGLTPL-HCGARSG 295
           +A+   G+T L H  A  G
Sbjct: 291 NAQDDAGMTSLMHVIAEGG 347
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|124517663|ref|NP_034860.2| annexin A1 [Mus musculus]
         (346 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

32521                                                                 202   1e-52
06659                                                                 118   3e-27
36934                                                                 117   7e-27
22178                                                                  99   3e-21
17882                                                                  56   2e-13
12136                                                                  73   2e-13
13827                                                                  59   4e-11
29756                                                                  52   4e-07
00843                                                                  32   0.30 
14944                                                                  29   2.7  
>32521
          Length = 1241

 Score =  202 bits (515), Expect = 1e-52,   Method: Compositional matrix adjust.
 Identities = 104/269 (38%), Positives = 162/269 (60%)
 Frame = +2

Query: 76  QRQQIKAAYLQENGKPLDEVLRKALTGHLEEVVLAMLKTPAQFDADELRGAMKGLGTDED 135
           QR++I   Y    GK L + L   L+G+ + + + ML  PA+FDA ++  A+KGLGTDE 
Sbjct: 5   QRREINLTYKTMFGKDLGKELSGELSGNFKTLCVEMLLGPAEFDAKQINKAVKGLGTDER 184

Query: 136 TLIEILTTRSNEQIREINRVYREELKRDLAKDITSDTSGDFRKALLALAKGDRCQDLSVN 195
            LIEI+ TR+N Q+  +   Y+   ++D+  DI  DTSG F++ L+   + +R +    +
Sbjct: 185 ALIEIICTRTNAQLTAMKEAYKTMYQKDVETDIEGDTSGPFKRLLIGCLQANRPEGQEFD 364

Query: 196 QDLADTDARALYEAGERRKGTDVNVFTTILTSRSFPHLRRVFQNYGKYSQHDMNKALDLE 255
           ++ A  DA+AL EAGE++ GTD + F  ++ SRSFP LR  FQ Y K +  D+  ++  E
Sbjct: 365 RNKAKQDAQALLEAGEKKWGTDESRFNVVIVSRSFPQLRATFQEYAKLANKDIEDSISSE 544

Query: 256 LKGDIEKCLTTIVKCATSTPAFFAEKLYEAMKGAGTRHKALIRIMVSRSEIDMNEIKVFY 315
           + GD +  + T+V+   S    FA +L+ AMKG GT    L+R++ SR E+DM +IK  +
Sbjct: 545 MSGDXKNGMLTVVRVIRSKATHFATELHRAMKGLGTDDDTLVRVVASRCEVDMVQIKEEF 724

Query: 316 QKKYGISLCQAILDETKGDYEKILVALCG 344
           Q+ +  +L   I+D+T GDY  +L  L G
Sbjct: 725 QRNFKQTLYSFIVDDTSGDYRLMLCNLIG 811

 Score = 38.9 bits (89), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 41/167 (24%), Positives = 72/167 (43%), Gaps = 9/167 (5%)
 Frame = +2

Query: 147 EQIREINRVYREELKRDLAKDITSDTSGDFRKALLALAKGDRCQDLSVNQDLADTDARAL 206
           EQ REIN  Y+    +DL K+++ + SG+F+   + +  G            A+ DA+ +
Sbjct: 2   EQRREINLTYKTMFGKDLGKELSGELSGNFKTLCVEMLLGP-----------AEFDAKQI 148

Query: 207 YEAGERRKGTDVNVFTTILTSRSFPHLRRVFQNYGKYSQHDMNKALDLELKGDIEKCLTT 266
            +A  +  GTD      I+ +R+   L  + + Y    Q D+   ++ +  G  ++ L  
Sbjct: 149 NKA-VKGLGTDERALIEIICTRTNAQLTAMKEAYKTMYQKDVETDIEGDTSGPFKRLLIG 325

Query: 267 IVKCATSTPAFF--------AEKLYEA-MKGAGTRHKALIRIMVSRS 304
            ++        F        A+ L EA  K  GT       ++VSRS
Sbjct: 326 CLQANRPEGQEFDRNKAKQDAQALLEAGEKKWGTDESRFNVVIVSRS 466
>06659
          Length = 776

 Score =  118 bits (296), Expect = 3e-27,   Method: Compositional matrix adjust.
 Identities = 81/223 (36%), Positives = 126/223 (56%), Gaps = 3/223 (1%)
 Frame = -3

Query: 123 LRGAMKGLGTDEDTLIEILTTRSNEQIREINRVYREELKRDLAKDITSDTSGDFRKALLA 182
           L  A+ G GTDE  LI+I+ TR N++++EI   Y+EE + +L +D+ +DT G FR+ +++
Sbjct: 774 LHDAISGAGTDEKCLIDIMCTRDNDEMKEIKEKYKEEFESELEEDLQADTGGYFRRLMIS 595

Query: 183 LAKGDRCQD--LSVNQDLADTDARALYEAGERRKGTDVNVFTTILTSRSFPHLRRVFQNY 240
           L  G R  D     N+D A  DA+   EAGE   GT+      IL   S   L +  + Y
Sbjct: 594 LCVGGRDYDNWWXANEDKAVEDAQKFLEAGENAWGTEEADMNAILCRTSPAQLCKTIEKY 415

Query: 241 GKYSQ-HDMNKALDLELKGDIEKCLTTIVKCATSTPAFFAEKLYEAMKGAGTRHKALIRI 299
            + ++   M +++  E   D+      IV+ A S P +FA +L +   G GT    LIRI
Sbjct: 414 EELTEGKTMEESIRSECSDDLXDGYLAIVESARSMPRYFARRLNDCFSGLGTSDNDLIRI 235

Query: 300 MVSRSEIDMNEIKVFYQKKYGISLCQAILDETKGDYEKILVAL 342
           +VSRSE+D+  IK  Y++ Y   L +A+  E  GDY+++L+A+
Sbjct: 234 IVSRSEVDLEAIKQAYEEMYEKPLTEAVESECGGDYKRLLLAI 106

 Score = 55.5 bits (132), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 38/130 (29%), Positives = 68/130 (52%), Gaps = 5/130 (3%)
 Frame = -3

Query: 59  GVDEATIIDILTKRTNAQRQQIKAAYLQ-ENGKPLDEVLRKALTGHLEEVVLAMLKT--- 114
           G +EA +  IL + + AQ  +    Y +   GK ++E +R   +  L +  LA++++   
Sbjct: 492 GTEEADMNAILCRTSPAQLCKTIEKYEELTEGKTMEESIRSECSDDLXDGYLAIVESARS 313

Query: 115 -PAQFDADELRGAMKGLGTDEDTLIEILTTRSNEQIREINRVYREELKRDLAKDITSDTS 173
            P  F A  L     GLGT ++ LI I+ +RS   +  I + Y E  ++ L + + S+  
Sbjct: 312 MPRYF-ARRLNDCFSGLGTSDNDLIRIIVSRSEVDLEAIKQAYEEMYEKPLTEAVESECG 136

Query: 174 GDFRKALLAL 183
           GD+++ LLA+
Sbjct: 135 GDYKRLLLAI 106

 Score = 30.4 bits (67), Expect = 1.0,   Method: Compositional matrix adjust.
 Identities = 23/64 (35%), Positives = 41/64 (64%)
 Frame = -3

Query: 282 LYEAMKGAGTRHKALIRIMVSRSEIDMNEIKVFYQKKYGISLCQAILDETKGDYEKILVA 341
           L++A+ GAGT  K LI IM +R   +M EIK  Y++++   L + +  +T G + +++++
Sbjct: 774 LHDAISGAGTDEKCLIDIMCTRDNDEMKEIKEKYKEEFESELEEDLQADTGGYFRRLMIS 595

Query: 342 LCGG 345
           LC G
Sbjct: 594 LCVG 583
>36934
          Length = 667

 Score =  117 bits (293), Expect = 7e-27,   Method: Compositional matrix adjust.
 Identities = 68/164 (41%), Positives = 99/164 (60%), Gaps = 1/164 (0%)
 Frame = +3

Query: 44  VSSDVAALHKAIMVKGV-DEATIIDILTKRTNAQRQQIKAAYLQENGKPLDEVLRKALTG 102
            + D   LHKA+   GV  E T+++I+ KR+N+QRQ +K  Y +   + L E L+  LTG
Sbjct: 18  AAEDAERLHKAMSGMGVTHEDTVLEIIIKRSNSQRQTLKKKYKEMYKRDLAEHLQSELTG 197

Query: 103 HLEEVVLAMLKTPAQFDADELRGAMKGLGTDEDTLIEILTTRSNEQIREINRVYREELKR 162
             EE++L +L  P ++DA  L  A+ GLGT+ED LI IL T + +++  +  VY++    
Sbjct: 198 DFEELILGLLMPPVEYDAFCLNKAVDGLGTNEDVLIGILCTANPKELSSVKEVYKKTYGE 377

Query: 163 DLAKDITSDTSGDFRKALLALAKGDRCQDLSVNQDLADTDARAL 206
           DL   I  DTSG F   LLAL++G+R Q  SVN+  A  DA+ L
Sbjct: 378 DLDSAIKGDTSGGFEDLLLALSRGERDQSKSVNEKEAKQDAQKL 509
>22178
          Length = 655

 Score = 98.6 bits (244), Expect = 3e-21,   Method: Compositional matrix adjust.
 Identities = 65/156 (41%), Positives = 92/156 (58%), Gaps = 5/156 (3%)
 Frame = +1

Query: 194 VNQDLADTDARALYEAG---ERRKG-TDVNVFTTILTSRSFP-HLRRVFQNYGKYSQHDM 248
           V+  +A  +A  LY+AG   +RR G  DV   +     R+   H  RV  N  +  +   
Sbjct: 1   VDPTIAMQEAHELYKAG*KGKRRDGRGDVQPHSVPEELRATAGHF*RVQANLRQGHRGRH 180

Query: 249 NKALDLELKGDIEKCLTTIVKCATSTPAFFAEKLYEAMKGAGTRHKALIRIMVSRSEIDM 308
            +  + +L G +      IV+ A +TPA+FAE+LY++MKGAGT  KALIR +VSRSE D+
Sbjct: 181 QE*DEWQLGGGL---FLAIVRVARNTPAYFAERLYKSMKGAGTNDKALIRAIVSRSENDL 351

Query: 309 NEIKVFYQKKYGISLCQAILDETKGDYEKILVALCG 344
             IK  +Q+ YG +L   I  +T GDY+KIL+ALCG
Sbjct: 352 GFIKQEFQRMYGKTLASYIKGDTSGDYKKILLALCG 459

 Score = 52.4 bits (124), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 31/82 (37%), Positives = 45/82 (54%)
 Frame = +1

Query: 102 GHLEEVVLAMLKTPAQFDADELRGAMKGLGTDEDTLIEILTTRSNEQIREINRVYREELK 161
           G    +V     TPA F A+ L  +MKG GT++  LI  + +RS   +  I + ++    
Sbjct: 211 GLFLAIVRVARNTPAYF-AERLYKSMKGAGTNDKALIRAIVSRSENDLGFIKQEFQRMYG 387

Query: 162 RDLAKDITSDTSGDFRKALLAL 183
           + LA  I  DTSGD++K LLAL
Sbjct: 388 KTLASYIKGDTSGDYKKILLAL 453

 Score = 32.7 bits (73), Expect = 0.21,   Method: Compositional matrix adjust.
 Identities = 18/58 (31%), Positives = 29/58 (50%)
 Frame = +2

Query: 124 RGAMKGLGTDEDTLIEILTTRSNEQIREINRVYREELKRDLAKDITSDTSGDFRKALL 181
           +G  + +GTDE+T   IL  R+  Q+R     YR+   +D+   I S+ SG+      
Sbjct: 47  QGERESVGTDEETFNRILCLRNYGQLRATFDAYRQISGKDIEDAIKSEMSGNLEAGFF 220
>17882
          Length = 489

 Score = 56.2 bits (134), Expect(2) = 2e-13,   Method: Compositional matrix adjust.
 Identities = 27/55 (49%), Positives = 38/55 (69%)
 Frame = -1

Query: 290 GTRHKALIRIMVSRSEIDMNEIKVFYQKKYGISLCQAILDETKGDYEKILVALCG 344
           GT    LIRI+VSRSEID+ +IK  Y  KY  +L  A+  +T GDY+++L+A+ G
Sbjct: 351 GTNDSRLIRIIVSRSEIDLQDIKDVYLSKYKKTLESAVASDTSGDYKRLLLAIVG 187

 Score = 37.0 bits (84), Expect(2) = 2e-13,   Method: Compositional matrix adjust.
 Identities = 15/41 (36%), Positives = 26/41 (63%)
 Frame = -2

Query: 247 DMNKALDLELKGDIEKCLTTIVKCATSTPAFFAEKLYEAMK 287
           D+  ++  E+ GD E  L  IV+C  + P +FA+KL++ +K
Sbjct: 479 DLLSSISSEMSGDFETGLRAIVRCMKNRPEYFADKLHDCIK 357

 Score = 45.8 bits (107), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 22/55 (40%), Positives = 36/55 (65%)
 Frame = -1

Query: 130 LGTDEDTLIEILTTRSNEQIREINRVYREELKRDLAKDITSDTSGDFRKALLALA 184
           LGT++  LI I+ +RS   +++I  VY  + K+ L   + SDTSGD+++ LLA+ 
Sbjct: 354 LGTNDSRLIRIIVSRSEIDLQDIKDVYLSKYKKTLESAVASDTSGDYKRLLLAIV 190
>12136
          Length = 445

 Score = 73.2 bits (178), Expect = 2e-13,   Method: Compositional matrix adjust.
 Identities = 39/104 (37%), Positives = 64/104 (61%), Gaps = 7/104 (6%)
 Frame = +3

Query: 92  LDEVLRKALTGHLEEVVLAMLKTPAQFDADELRGAMKGLGTDEDTLIEILTTRSNEQIRE 151
           L E ++  L+G  +E+V+A+   PA++DA  ++ A+ G GTDE  L+EIL TR+N QI+E
Sbjct: 3   LIEEIKGELSGDYKELVMALFVAPAEYDAWCIKEAIYGPGTDEMALMEILMTRTNAQIKE 182

Query: 152 INRVYREELK-------RDLAKDITSDTSGDFRKALLALAKGDR 188
           +  +Y   L          + +DI  D SGDF++ L++ ++G R
Sbjct: 183 LRSIYPSVLNDHYHGRTPKIEQDIEDDCSGDFKRLLISASQGGR 314
>13827
          Length = 483

 Score = 58.5 bits (140), Expect(2) = 4e-11,   Method: Compositional matrix adjust.
 Identities = 25/59 (42%), Positives = 41/59 (69%)
 Frame = -1

Query: 287 KGAGTRHKALIRIMVSRSEIDMNEIKVFYQKKYGISLCQAILDETKGDYEKILVALCGG 345
           +G GT  + LIR++V+R E+DM +IK  +Q +YG +L   + D+  GDY ++++AL GG
Sbjct: 444 RGMGTDDRTLIRVVVTRCEVDMKQIKQEFQNRYGQALEAFVRDDISGDYRRLMLALVGG 268

 Score = 26.2 bits (56), Expect(2) = 4e-11,   Method: Compositional matrix adjust.
 Identities = 9/17 (52%), Positives = 13/17 (76%)
 Frame = -3

Query: 276 AFFAEKLYEAMKGAGTR 292
            +FA++LY +MKG G R
Sbjct: 478 GYFADRLYHSMKGDGHR 428

 Score = 44.3 bits (103), Expect = 7e-05,   Method: Compositional matrix adjust.
 Identities = 20/59 (33%), Positives = 36/59 (61%)
 Frame = -1

Query: 128 KGLGTDEDTLIEILTTRSNEQIREINRVYREELKRDLAKDITSDTSGDFRKALLALAKG 186
           +G+GTD+ TLI ++ TR    +++I + ++    + L   +  D SGD+R+ +LAL  G
Sbjct: 444 RGMGTDDRTLIRVVVTRCEVDMKQIKQEFQNRYGQALEAFVRDDISGDYRRLMLALVGG 268
>29756
          Length = 496

 Score = 52.0 bits (123), Expect = 4e-07,   Method: Compositional matrix adjust.
 Identities = 25/47 (53%), Positives = 28/47 (59%)
 Frame = +3

Query: 38  PYPSFNVSSDVAALHKAIMVKGVDEATIIDILTKRTNAQRQQIKAAY 84
           PYP FN   DV  L KA+   G DE  IIDIL  RT+ QRQ +K  Y
Sbjct: 252 PYPRFNAEEDVQKLRKAMKGFGTDEKAIIDILGYRTSDQRQNLKLMY 392

 Score = 41.6 bits (96), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 24/69 (34%), Positives = 39/69 (56%), Gaps = 1/69 (1%)
 Frame = +3

Query: 116 AQFDADELRGAMKGLGTDEDTLIEILTTRSNEQIREINRVYREELKRDLAKDI-TSDTSG 174
           A+ D  +LR AMKG GTDE  +I+IL  R+++Q + +  +Y+    +         + +G
Sbjct: 270 AEEDVQKLRKAMKGFGTDEKAIIDILGYRTSDQRQNLKLMYKNLFWKRFGAGF*RVN*AG 449

Query: 175 DFRKALLAL 183
            F  A+LAL
Sbjct: 450 AFEDAMLAL 476
>00843
          Length = 1273

 Score = 32.3 bits (72), Expect = 0.30,   Method: Compositional matrix adjust.
 Identities = 14/33 (42%), Positives = 20/33 (60%)
 Frame = +3

Query: 252 LDLELKGDIEKCLTTIVKCATSTPAFFAEKLYE 284
           +D  +KGDI K L ++  C  S   F+ E+LYE
Sbjct: 30  IDTLVKGDIAKWLVSVFFCYLSISVFY*ERLYE 128
>14944
          Length = 412

 Score = 29.3 bits (64), Expect = 2.7,   Method: Compositional matrix adjust.
 Identities = 12/20 (60%), Positives = 14/20 (70%)
 Frame = -1

Query: 12  RFLENQEQEYVQAVKSYKGG 31
           RFLE + Q YVQ +  YKGG
Sbjct: 271 RFLETERQAYVQQIYKYKGG 212
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|19526848|ref|NP_598445.1| MOCO sulphurase C-terminal
domain containing 2 [Mus musculus]
         (338 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

20265                                                                 203   1e-52
11105                                                                 162   2e-45
19971                                                                  32   0.51 
28965                                                                  29   3.1  
>20265
          Length = 1109

 Score =  203 bits (516), Expect = 1e-52,   Method: Compositional matrix adjust.
 Identities = 116/293 (39%), Positives = 168/293 (57%), Gaps = 6/293 (2%)
 Frame = +1

Query: 50  QLQQVGTVSKVWIYPIKSCKGVSVCETECTDMGLRCGKVRDRFWMVVKEDGHMVTARQEP 109
           ++ QVGTV++++ YPIKSC+G SV    CT +GL+ G   DR W+VV+ +G  +T RQ  
Sbjct: 97  KMVQVGTVTQLFCYPIKSCRGFSVPSGFCTRLGLKTGGAVDRHWVVVRSNGDFITQRQFA 276

Query: 110 RLVLVSITLENNYLTLEAPGMEQIVLPIK--LPSSNKIHNCRLFGLDIKGRDCGDEVAQW 167
           R+ L+   +  + ++L APGM  + +P+   +     + NCR++   +K  D G E  QW
Sbjct: 277 RMSLIHTEVAASTMSLTAPGMPPLSVPLSPVVDYGENVLNCRVWHNALKAVDVGREAGQW 456

Query: 168 FTNYLKTQAYRLVQFDTSM-KGRTTKKLYP-SESYLQNYEVAYPDCSPVHLISEASLVDL 225
            + +L+    RL+    SM + R   K  P     L   + A+ D     + +E+SL  L
Sbjct: 457 LSTFLQEPGLRLLWSAPSMPRARIALKAKPWGNPALPGDQAAFTDYCSYLVATESSLTSL 636

Query: 226 NTRLKKKVKMEYFRPNIVVSGCEAFEEDTWDELLIGDVEMKRVLS-CPRCVLTTVDPDTG 284
           N RLK+ V M  FRPNIV+SGC AF+EDTW+ + IGD    R+L  C RC L TV  D G
Sbjct: 637 NQRLKQPVTMASFRPNIVISGCPAFDEDTWEVIRIGDTATFRMLDPCTRCQLITVHQDEG 816

Query: 285 IID-RKEPLETLKSYRLCDPSVKSIYQSSPLFGMYFSVEKLGSLRVGDPVYRM 336
             D   EPL TLK++R C P     Y  SPLFG+  + +  G ++VGDPV+ +
Sbjct: 817 ERDPDSEPLXTLKTFR-CFPK----YGPSPLFGVNATGDNEGVVKVGDPVFAI 960
>11105
          Length = 1391

 Score =  162 bits (411), Expect(2) = 2e-45,   Method: Compositional matrix adjust.
 Identities = 90/237 (37%), Positives = 131/237 (55%), Gaps = 4/237 (1%)
 Frame = -3

Query: 64   PIKSCKGVSVCETECTDMGLRCGKVRDRFWMVVKEDGHMVTARQEPRLVLVSITLENNYL 123
            PIKS +G+ V E +CT +G  C    DR W V   +G  +T RQEP + L+ + ++   +
Sbjct: 1389 PIKSFRGIQVNEGDCTALGFSCFGATDRHWTVATANGVYLTQRQEPSMALIQVQVKGELI 1210

Query: 124  TLEAPGMEQIVLPIKLP-SSNKIHNCRLFGLDIKGRDCGDEVAQWFTNYLKTQAYRLVQF 182
             L+AP ME I +P+  P +++ +    +    I   DCGD+VA W  +Y K +  RL   
Sbjct: 1209 QLDAPNMESITIPLNPPVTADMLSQVTVKTDTIPSLDCGDKVAAWLCSYFKREGLRLHFS 1030

Query: 183  DTSMKGRTTK--KLYPSESYLQNYEVAYPDCSPVHLISEASLVDLNTRLKKKVKMEYFRP 240
              S++ R  +  K   +   L     A  D     ++S  SL  LN RL K V +  FR 
Sbjct: 1029 APSLEKRQCQLNKKNWNHPALAGDMTALSDYCGYMVLSNPSLSALNQRLDKPVPVSNFRA 850

Query: 241  NIVVSGCEAFEEDTWDELLIGDVEMKRVLSCPRCVLTTVDPDTGIID-RKEPLETLK 296
            NI+V  C+AF+ED W  + IGDVE++ + +C RCVL TVD D G+ D ++EPL TLK
Sbjct: 849  NIIVDSCQAFDEDNWASVRIGDVELRALDACTRCVLVTVDQDKGVKDEQEEPLTTLK 679

 Score = 37.7 bits (86), Expect(2) = 2e-45,   Method: Compositional matrix adjust.
 Identities = 17/39 (43%), Positives = 25/39 (64%)
 Frame = -1

Query: 296 KSYRLCDPSVKSIYQSSPLFGMYFSVEKLGSLRVGDPVY 334
           K +RL DP     Y   P FG+ F+++K G ++VGDP+Y
Sbjct: 680 KKFRLKDP-----YGPKPCFGVNFTLDKPGKIKVGDPIY 579
>19971
          Length = 412

 Score = 31.6 bits (70), Expect = 0.51,   Method: Compositional matrix adjust.
 Identities = 12/25 (48%), Positives = 15/25 (60%)
 Frame = -1

Query: 155 IKGRDCGDEVAQWFTNYLKTQAYRL 179
           I   DCGD+VA W  +Y K +  RL
Sbjct: 388 IPSLDCGDKVAAWLCSYFKREGLRL 314
>28965
          Length = 421

 Score = 28.9 bits (63), Expect = 3.1,   Method: Compositional matrix adjust.
 Identities = 16/39 (41%), Positives = 23/39 (58%), Gaps = 2/39 (5%)
 Frame = -1

Query: 288 RKEPLETLKSYRLCDPSVKSIYQSS--PLFGMYFSVEKL 324
           R  P++TL+S+RLC  SV    QSS   L    F+++ L
Sbjct: 406 RLVPMDTLQSHRLCAQSVHLFLQSSKVTLHSFMFTLQCL 290
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|21313158|ref|NP_080207.1| RAB, member of RAS oncogene
family-like 4 [Mus musculus]
         (186 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

30760                                                                 201   1e-52
34468                                                                  76   1e-14
26083                                                                  72   2e-13
14456                                                                  65   2e-11
33794                                                                  64   5e-11
07465                                                                  64   5e-11
13901                                                                  63   5e-11
08428                                                                  61   3e-10
33374                                                                  61   3e-10
05468                                                                  59   1e-09
32723                                                                  58   2e-09
01398                                                                  57   3e-09
26536                                                                  56   7e-09
07580                                                                  54   4e-08
12339                                                                  54   5e-08
01095                                                                  53   8e-08
13745                                                                  52   1e-07
13750                                                                  52   1e-07
11728                                                                  45   2e-05
33380                                                                  44   3e-05
27191                                                                  42   1e-04
29380                                                                  42   2e-04
19656                                                                  42   2e-04
31291                                                                  39   0.001
35581                                                                  39   0.001
04583                                                                  27   4.7  
12231                                                                  27   5.6  
33902                                                                  27   7.0  
>30760
          Length = 596

 Score =  201 bits (511), Expect = 1e-52,   Method: Compositional matrix adjust.
 Identities = 91/176 (51%), Positives = 126/176 (71%)
 Frame = -1

Query: 4   LAAKCILAGDPAVGKTALVQMFRSDGTHFQKNYTLTTGVDLVVKTVPVLDTNDSVELFIF 63
           L AKCI+ GD  VGK+++ Q+F SD  HF KNY++TTGV+++VK V + D+ D VEL++F
Sbjct: 533 LRAKCIVTGDSGVGKSSICQVFHSDSAHFPKNYSMTTGVEVLVKLVNIPDSRDQVELYLF 354

Query: 64  DSAGKELFSEMLDKLWENPNVLCLVYDVTNEQSFISCTKWLEKVRSQTSGISLPGVLVGT 123
           DSAGKE+FSE + K W+ P+V+ +VYDVT+E SF  C +WLE+VR+      +PGVLV  
Sbjct: 353 DSAGKEIFSENVTKFWDQPSVVMVVYDVTDETSFSGCVRWLERVRAAKPNTVIPGVLVAN 174

Query: 124 KTDLAGRQTVDSAQAQVWALSQGLEFFETSVKEMDNYEAPFHCLAKQFYQLYREKV 179
           KTDL  R+ V   + +  A S GLE+FE S KEM N + PF CLA  F++LY+E++
Sbjct: 173 KTDLDERRRVSRKEGKDLAQSHGLEYFECSAKEMQNTDTPFFCLAHAFHKLYQEQL 6
>34468
          Length = 1502

 Score = 75.9 bits (185), Expect = 1e-14,   Method: Compositional matrix adjust.
 Identities = 49/151 (32%), Positives = 79/151 (52%), Gaps = 1/151 (0%)
 Frame = +1

Query: 7   KCILAGDPAVGKTALVQMFRSDGTHFQKNYTLTTGVDLVVKTVPVLDTNDSVELFIFDSA 66
           K I+ GD  VGKT L   +R     F      T GVD   K++ V   ++ ++L ++D+A
Sbjct: 499 KIIVIGDSNVGKTCLT--YRFCLGKFPDKTEATIGVDFREKSIQV--DSEHLKLQLWDTA 666

Query: 67  GKELFSE-MLDKLWENPNVLCLVYDVTNEQSFISCTKWLEKVRSQTSGISLPGVLVGTKT 125
           G+E F + M+   + N + +  VYD+T   SF +   W+E+         +P +LVG K 
Sbjct: 667 GQERFRKSMVQHYYRNVHAVVFVYDMTKMSSFENMPAWIEECDRHNLTKYIPRILVGNKC 846

Query: 126 DLAGRQTVDSAQAQVWALSQGLEFFETSVKE 156
           D+  R  V++  AQ +A +  +  FETS K+
Sbjct: 847 DVVERIAVNTNLAQKFADAHNMPLFETSAKD 939
>26083
          Length = 432

 Score = 71.6 bits (174), Expect = 2e-13,   Method: Compositional matrix adjust.
 Identities = 40/118 (33%), Positives = 68/118 (57%)
 Frame = +1

Query: 7   KCILAGDPAVGKTALVQMFRSDGTHFQKNYTLTTGVDLVVKTVPVLDTNDSVELFIFDSA 66
           K +  G+ +VGKT+L+  F  D   F   Y  T G+D + KT+ + D   ++ L ++D+A
Sbjct: 82  KLVFLGEQSVGKTSLITRFMYDS--FDNTYQATIGIDFLSKTMYLEDR--TIRLQLWDTA 249

Query: 67  GKELFSEMLDKLWENPNVLCLVYDVTNEQSFISCTKWLEKVRSQTSGISLPGVLVGTK 124
           G+E F  ++     + +V  +VYD+TN  SF   +KW++ VR++  G  +  +LVG K
Sbjct: 250 GQERFRSLIPSYIRDSSVAVVVYDITNANSFHQTSKWIDDVRTE-RGSDVIIMLVGNK 420
>14456
          Length = 1867

 Score = 64.7 bits (156), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 46/154 (29%), Positives = 80/154 (51%), Gaps = 4/154 (2%)
 Frame = -1

Query: 15   AVGKTALVQMFRSDGTHFQKNYTLTTGVDLVVKTVPVLDTNDSVELFIFDSAGKELFSEM 74
             VGK++L+  F S+    Q  +T+  GV+ + K V V D  ++  + I+D+AG+E F  +
Sbjct: 1111 GVGKSSLMNRFVSNKFDAQSFHTI--GVEFLNKDVVVDD--ETYTMQIWDTAGQERFKSL 944

Query: 75   LDKLWENPNVLCLVYDVTNEQSFISCTKWLEKV---RSQTSGISLPGVLVGTKTDLAGRQ 131
                +   +   L + V + QSF + + W ++         G++ P V++G K D+ GRQ
Sbjct: 943  RTPFYRGADCCLLTFSVDSMQSFRNLSMWRKEFLYYADIQDGVTFPFVVLGNKIDVEGRQ 764

Query: 132  TVDSAQAQVWALSQ-GLEFFETSVKEMDNYEAPF 164
             V + +A+ W  +     +FETS K+  N E  F
Sbjct: 763  -VTNEEARSWCTANSNAPYFETSAKDATNVEKAF 665
>33794
          Length = 779

 Score = 63.5 bits (153), Expect = 5e-11,   Method: Compositional matrix adjust.
 Identities = 36/107 (33%), Positives = 57/107 (53%)
 Frame = -1

Query: 47  KTVPVLDTNDSVELFIFDSAGKELFSEMLDKLWENPNVLCLVYDVTNEQSFISCTKWLEK 106
           KT  +L     V+L I+D++G+  F  ++         + LVYD+TN+ SF    +WL++
Sbjct: 683 KTTTILLEGKRVKLQIWDTSGQGRFCTIIRSYSRGAQGIILVYDITNKWSFDGIDRWLKE 504

Query: 107 VRSQTSGISLPGVLVGTKTDLAGRQTVDSAQAQVWALSQGLEFFETS 153
           V     GI  P VLVG +  LA ++ V + QA+ +A    +  FE S
Sbjct: 503 VEEHAPGI--PKVLVGNRLHLAYKRQVAAKQAETYASRNNMSCFEIS 369
>07465
          Length = 1103

 Score = 63.5 bits (153), Expect = 5e-11,   Method: Compositional matrix adjust.
 Identities = 43/144 (29%), Positives = 67/144 (46%), Gaps = 1/144 (0%)
 Frame = +3

Query: 32  FQKNYTLTTGVDLVVKTVPVLDTNDSVELFIFDSAGKELFSEMLDKLWENPNVLCLVYDV 91
           F K+Y  T GVD + + + V    + V L ++D+AG+E F  +    +       L +  
Sbjct: 273 FTKDYKKTIGVDFLERQIEV--GGEDVRLMLWDTAGQEEFDAITKAYYRGAQACVLAFST 446

Query: 92  TNEQSFISCTKWLEKVRSQTSGISLPGVLVGTKTDLAGRQTVDSAQAQVWALSQGLEFFE 151
            +  SF +   W  KV  +   I +  V+V  K DL     V   +A+  A    L F+ 
Sbjct: 447 VDRDSFEALETWKRKVEDEVGEIGM--VIVQNKIDLIDDAVVRPEEAENLAKKLRLRFYR 620

Query: 152 TSVKEMDNYEAPFHCLAKQF-YQL 174
           TSVKE  N +  F  LA ++ +QL
Sbjct: 621 TSVKENMNVDEVFRYLADKYLHQL 692
>13901
          Length = 962

 Score = 63.2 bits (152), Expect = 5e-11,   Method: Compositional matrix adjust.
 Identities = 30/97 (30%), Positives = 60/97 (61%)
 Frame = -3

Query: 7   KCILAGDPAVGKTALVQMFRSDGTHFQKNYTLTTGVDLVVKTVPVLDTNDSVELFIFDSA 66
           K I+ GDP VGKT+ VQ + +D   F+++Y +T GVD  +K +   D  + ++L ++D A
Sbjct: 282 KVIIIGDPTVGKTSFVQRYVNDS--FRRDYKMTIGVDFALKVIRWSDKCN-IKLQLWDIA 112

Query: 67  GKELFSEMLDKLWENPNVLCLVYDVTNEQSFISCTKW 103
           G+E F+ M    +++ +   +++D+T + ++ +  +W
Sbjct: 111 GQERFTSMTRVYYKDAHACIVMFDLTQKNTYQNAIRW 1
>08428
          Length = 1109

 Score = 61.2 bits (147), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 50/168 (29%), Positives = 78/168 (46%), Gaps = 3/168 (1%)
 Frame = -3

Query: 7    KCILAGDPAVGKTALVQMFRSDGTHFQKNYTLTTGVDLVVKTVPVLDTNDSVELFIFDSA 66
            K  L GD  VGK+++V  F +    ++ +   T G   + K++ V+D        I+D+A
Sbjct: 1065 KVCLLGDSGVGKSSIVLRFVTG--SYRPSQESTIGASFMSKSL-VVD-GAGYRFQIWDTA 898

Query: 67   GKELFSEMLDKLWENPNVLCLVYDVTNEQSFISCTKWLEKVRSQTSGISLPGV---LVGT 123
            G+E F  +    +       +VYDVT  ++F S   W++++RS       P +   + G 
Sbjct: 897  GQEKFRALAPMYYRGAAAAVIVYDVTRPRTFKSVKSWIQELRS----FGPPNIVLAIAGN 730

Query: 124  KTDLAGRQTVDSAQAQVWALSQGLEFFETSVKEMDNYEAPFHCLAKQF 171
            K DL   + V    AQ +A S    F ETS     N E  F  LA+Q 
Sbjct: 729  KCDLEELREVVEKDAQEYASSISAIFGETSAMTAVNVEEMFTELARQL 586
>33374
          Length = 489

 Score = 61.2 bits (147), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 35/112 (31%), Positives = 62/112 (55%)
 Frame = +1

Query: 44  LVVKTVPVLDTNDSVELFIFDSAGKELFSEMLDKLWENPNVLCLVYDVTNEQSFISCTKW 103
            + +TV + DT  +V+  I+D+AG+E +  +    +       +VYD+TN+ +F     W
Sbjct: 139 FLTQTVCLDDT--TVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNQDTFGRAKTW 312

Query: 104 LEKVRSQTSGISLPGVLVGTKTDLAGRQTVDSAQAQVWALSQGLEFFETSVK 155
           +++++ Q S  ++   L G K DLA ++ V+  +AQ +A    L F ETS K
Sbjct: 313 VKELQRQASP-NIVIALAGNKADLANKRMVEFEEAQAYAEENSLLFMETSAK 465
>05468
          Length = 1558

 Score = 58.9 bits (141), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 45/158 (28%), Positives = 80/158 (50%), Gaps = 5/158 (3%)
 Frame = -3

Query: 7    KCILAGDPAVGKTALVQMFRSDGTHFQKNYTLTTGVDLVVKTVPVLDTNDSVELFIFDSA 66
            K ++ G+   GKT++++ +      F ++Y  T GVD  +K +   D +  + L ++D A
Sbjct: 1535 KILVIGELGTGKTSIIKRYVHQ--FFSQHYRATIGVDFALKVLN-WDADTLIRLQLWDIA 1365

Query: 67   GKELFSEMLDKLWENPNVLCLVYDVTNEQSFISCTKWLEKVRSQ---TSGISLPGVLVGT 123
            G+E F  M    ++      +V+DVT   +F + TKW   + S+     G  +P VL+  
Sbjct: 1364 GQERFGNMTRVYYKEAVGAFVVFDVTRASTFDAVTKWKNDLDSKVQLADGSPVPCVLLAN 1185

Query: 124  KTDLAGRQTV-DSAQAQVWALSQG-LEFFETSVKEMDN 159
            K D A    V +++Q   +   +G + ++ETS KE  N
Sbjct: 1184 KCDQAKEGLVNNTSQMDEFCSEKGFIGWYETSAKENIN 1071
>32723
          Length = 384

 Score = 58.2 bits (139), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 32/104 (30%), Positives = 53/104 (50%)
 Frame = +2

Query: 68  KELFSEMLDKLWENPNVLCLVYDVTNEQSFISCTKWLEKVRSQTSGISLPGVLVGTKTDL 127
           +E F  +    + + N L LVYDV ++QS+ S  +W+ ++    +G  +   LVG K D 
Sbjct: 2   QERFRSITQSYYRSANALILVYDVCSQQSYESLPQWIHEI-ELYAGTKVLAFLVGNKIDQ 178

Query: 128 AGRQTVDSAQAQVWALSQGLEFFETSVKEMDNYEAPFHCLAKQF 171
             ++ + +   + +A    + F ETS KE DN E  F  +A Q 
Sbjct: 179 TDKREIPTHIGKEFAERYEMRFLETSAKEADNVEKLFSTIAYQL 310
>01398
          Length = 1421

 Score = 57.4 bits (137), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 31/106 (29%), Positives = 53/106 (50%)
 Frame = -2

Query: 68   KELFSEMLDKLWENPNVLCLVYDVTNEQSFISCTKWLEKVRSQTSGISLPGVLVGTKTDL 127
            +E F  +    + N   + +VYD+T   +F +  +W E+ R+         +++G K+D 
Sbjct: 1420 QERFRSITRSYYRNSVGVIIVYDITKRSTFENLKQWYEEARNHIEPHKAIFLVLGHKSDR 1241

Query: 128  AGRQTVDSAQAQVWALSQGLEFFETSVKEMDNYEAPFHCLAKQFYQ 173
               + V + + + +A   GL+FFETS K   N E  F  +AK  YQ
Sbjct: 1240 EDARQVTAREGRRFAEMHGLKFFETSAKSGHNIEDVFAQIAKDTYQ 1103
>26536
          Length = 829

 Score = 56.2 bits (134), Expect = 7e-09,   Method: Compositional matrix adjust.
 Identities = 35/110 (31%), Positives = 55/110 (50%), Gaps = 3/110 (2%)
 Frame = +2

Query: 63  FDSAGKELFSEMLDKLWENPNVLCLVYDVTNEQSFISCT---KWLEKVRSQTSGISLPGV 119
            D+AG+E +S M +    + +   +VY VT+  SF       +WL + + +TS   +  V
Sbjct: 143 LDTAGQEEYSSMREHYTRSGDGFIVVYSVTDVTSFQEAEAVFRWLTRFQDETS---IHAV 313

Query: 120 LVGTKTDLAGRQTVDSAQAQVWALSQGLEFFETSVKEMDNYEAPFHCLAK 169
           L G KTDL   + V   + +  A   G+ +FETS K  DN    +H L +
Sbjct: 314 LCGNKTDLTSDRKVTPEEGRKMADRLGMLYFETSAKTGDNVSQVYHGLLR 463
>07580
          Length = 921

 Score = 53.9 bits (128), Expect = 4e-08,   Method: Compositional matrix adjust.
 Identities = 36/112 (32%), Positives = 49/112 (43%)
 Frame = +3

Query: 60  LFIFDSAGKELFSEMLDKLWENPNVLCLVYDVTNEQSFISCTKWLEKVRSQTSGISLPGV 119
           L I D+AG E F+ M D   +N     L Y +T + +F    +  E++        +P +
Sbjct: 210 LEILDTAGTEQFTAMRDLYMKNGQGFLLAYSITAQSTFNDLQELREQILRVKDTDDVPML 389

Query: 120 LVGTKTDLAGRQTVDSAQAQVWALSQGLEFFETSVKEMDNYEAPFHCLAKQF 171
           LVG K DL   + V   Q Q  A S    F ETS K   N    F  L +Q 
Sbjct: 390 LVGNKCDLEDERVVGKDQGQGLARSFSCAFLETSAKARINVNEIFMDLVRQI 545
>12339
          Length = 578

 Score = 53.5 bits (127), Expect = 5e-08,   Method: Compositional matrix adjust.
 Identities = 35/106 (33%), Positives = 52/106 (49%), Gaps = 4/106 (3%)
 Frame = -2

Query: 68  KELFSEMLDKLWENPNVLCLVYDVTNEQSFISCTKWLEKVRSQTSGIS---LPGVLVGTK 124
           +E F  +    +   +   LVYDVT  ++F S   W  +  +Q S       P V++G K
Sbjct: 577 QERFQSLGVAFYRGADCCILVYDVTEXKTFDSLDSWQREFLNQASPRDPEHFPFVVIGNK 398

Query: 125 TDLAGRQTVDSAQAQVWALSQ-GLEFFETSVKEMDNYEAPFHCLAK 169
            DL  R  V + + Q W  ++ G+ +FETS KE  N E  F  +AK
Sbjct: 397 IDLDNR-VVTAKRGQGWCSTKGGIPYFETSAKEAINVEQAFQTVAK 263
>01095
          Length = 1745

 Score = 52.8 bits (125), Expect = 8e-08,   Method: Compositional matrix adjust.
 Identities = 30/88 (34%), Positives = 47/88 (53%), Gaps = 3/88 (3%)
 Frame = -1

Query: 87   LVYDVTNEQSFISCTKWLEKVRSQTSGISLPGV---LVGTKTDLAGRQTVDSAQAQVWAL 143
            +VYD+TN+ +F     W+++++ Q S    P +   L G K DLA ++ V+  +AQ +A 
Sbjct: 1745 VVYDITNQDTFGRAKTWVKELQRQAS----PNIVIALAGNKADLANKRMVEFEEAQAYAE 1578

Query: 144  SQGLEFFETSVKEMDNYEAPFHCLAKQF 171
               L F ETS K   N    F  +AK+ 
Sbjct: 1577 ENSLLFMETSAKTAMNVNDIFLAIAKKL 1494
>13745
          Length = 1045

 Score = 52.4 bits (124), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 36/106 (33%), Positives = 52/106 (49%), Gaps = 4/106 (3%)
 Frame = +2

Query: 68  KELFSEMLDKLWENPNVLCLVYDVTNEQSFISCTKWLEKVRSQTSGIS---LPGVLVGTK 124
           +E F  +    +   +   LVYDVT   SF +   W ++   Q S       P V++G K
Sbjct: 2   QERFQSLGVAFYRGADCCVLVYDVTAPNSFKNLDSWRDEFLIQASPRDPEHFPFVVLGNK 181

Query: 125 TDLAGRQTVDSAQAQVWALSQG-LEFFETSVKEMDNYEAPFHCLAK 169
            DL  RQ V + +AQ W  S+  + ++ETS KE  N E  F  +AK
Sbjct: 182 VDLDNRQ-VSTRRAQQWCQSKNDIPYYETSAKEGINVEMAFQTIAK 316
>13750
          Length = 503

 Score = 52.0 bits (123), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 44/155 (28%), Positives = 72/155 (46%), Gaps = 9/155 (5%)
 Frame = -2

Query: 31  HFQKNYTLTTGVDLVVKTVPVL--DTNDS------VELFIFDSAGKELFSEMLDKLWENP 82
            +QK + +    D  + T+ VL  + N+S      V   ++D+ G E +  +    +   
Sbjct: 484 RYQKGFFM----DRTMPTIAVLCSEFNESRTDPLNVRYTLWDTGGAETYRSLWVSHFRGA 317

Query: 83  NVLCLVYDVTNEQSFISCTK-WLEKVRSQTSGISLPGVLVGTKTDLAGRQTVDSAQAQVW 141
            V  LVYDVT E SF++ T  W + +        +  + VG+KTDL   + + + + Q +
Sbjct: 316 QVALLVYDVTCEWSFLTATTVWRKALMKNIPEAQV--IFVGSKTDLEENRVISTERGQAF 143

Query: 142 ALSQGLEFFETSVKEMDNYEAPFHCLAKQFYQLYR 176
           A   G  FFETS     N +A F  +A    +L R
Sbjct: 142 ATQCGYTFFETSSVTGKNVDAVFWEIAFILARLQR 38
>11728
          Length = 635

 Score = 44.7 bits (104), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 35/128 (27%), Positives = 62/128 (48%), Gaps = 5/128 (3%)
 Frame = -1

Query: 5   AAKCILAGDPAVGKTALVQMFRSDGTHFQKNYTLTT----GVDLVVKTVPVLDTNDSVEL 60
           A KC++ GD AVGKT L+  + ++   F   Y  T       +++V + P       + L
Sbjct: 491 AIKCVVVGDGAVGKTCLLISYTTNA--FPGEYIPTVFDNYSANVMVDSKP-------INL 339

Query: 61  FIFDSAGKELFSEMLDKLWENPNVLCLVYDVTNEQSFISC-TKWLEKVRSQTSGISLPGV 119
            ++D+AG+E +  +    +   +V  + + + +  SF +   KW  +V       + P +
Sbjct: 338 GLWDTAGQEDYDRLRPLSYPQTDVFLICFSLISPASFENVKAKWYPEVSHHCP--NTPII 165

Query: 120 LVGTKTDL 127
           LVGTK DL
Sbjct: 164 LVGTKLDL 141
>33380
          Length = 282

 Score = 44.3 bits (103), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 26/78 (33%), Positives = 42/78 (53%)
 Frame = +3

Query: 50  PVLDTNDSVELFIFDSAGKELFSEMLDKLWENPNVLCLVYDVTNEQSFISCTKWLEKVRS 109
            V   +  V+L I+D+AG+E +  +    +       L+YDVTNE+SF +   W  ++++
Sbjct: 36  TVFRQDKRVKLQIWDTAGQERYRTITTAYYRGAMGFILMYDVTNEESFNAVQDWCTQIKT 215

Query: 110 QTSGISLPGVLVGTKTDL 127
             S  +   VLVG K DL
Sbjct: 216 Y-SWDNAQVVLVGNKCDL 266
>27191
          Length = 443

 Score = 42.4 bits (98), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 29/109 (26%), Positives = 58/109 (53%), Gaps = 2/109 (1%)
 Frame = +1

Query: 18  KTALVQMFRSDGTHFQKNYTLTTGVD--LVVKTVPVLDTNDSVELFIFDSAGKELFSEML 75
           KT L++ F    + F + Y  T GVD    ++TV  +D    + + ++D +G   + ++ 
Sbjct: 1   KTCLIKHFCE--SKFNQGYQPTVGVDYGFKIQTVNGVD----MRVHMWDLSGSNEYLDVR 162

Query: 76  DKLWENPNVLCLVYDVTNEQSFISCTKWLEKVRSQTSGISLPGVLVGTK 124
           ++L+   + + +V+DV+N  SF +   WL ++    +G  L  V+VG +
Sbjct: 163 NELYTGSDAIFIVFDVSNTPSFEALDSWLREINRFATGSPL-NVIVGNR 306
>29380
          Length = 853

 Score = 41.6 bits (96), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 30/89 (33%), Positives = 42/89 (47%), Gaps = 1/89 (1%)
 Frame = -2

Query: 86  CLVYDVTNEQSFISCTKWLEKVRSQTSGISLPGVLVGTKTDLAGR-QTVDSAQAQVWALS 144
            +VYDV    +F     W++++R Q +  S+  +L G K DLA + + V    AQ +A  
Sbjct: 840 IIVYDVNIADTFSRALAWVKELRQQNTE-SVLIILAGNKVDLATQHRAVSFEDAQSFARE 664

Query: 145 QGLEFFETSVKEMDNYEAPFHCLAKQFYQ 173
            GL F E S K        F  LA Q  Q
Sbjct: 663 NGLLFAEVSAKTGMAVNEIFMTLANQLIQ 577
>19656
          Length = 428

 Score = 41.6 bits (96), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 31/114 (27%), Positives = 51/114 (44%), Gaps = 1/114 (0%)
 Frame = +3

Query: 1   MVKLAAKCILAGDPAVGKTALVQMFRSDGTHFQKNYTLTTGVDLVVKTVPVLDTNDSVEL 60
           M   A KC++ GD AVGKT L+  + ++   F   Y  T   +       V+     V L
Sbjct: 99  MAMQAIKCVVVGDGAVGKTCLLISYTTNA--FPGEYIPTVFDNYSAN---VMVDGRPVNL 263

Query: 61  FIFDSAGKELFSEMLDKLWENPNVLCLVYDVTNEQSFISC-TKWLEKVRSQTSG 113
            ++D+AG+E +  +    +   +V  L + V +  SF +   KW  +V     G
Sbjct: 264 GLWDTAGQEDYDRLRPLSYPQTDVFLLCFSVASPASFENIRAKWYPEVNHHCPG 425
>31291
          Length = 446

 Score = 38.9 bits (89), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 35/120 (29%), Positives = 57/120 (47%), Gaps = 15/120 (12%)
 Frame = -1

Query: 60  LFIFDSAGKELFSEMLDKLWENPNVLCLVYDVTNEQSFISC-TKWLEKVRSQTSGISLPG 118
           L ++D+AG+E +  +    + N +V  L + + +E S  +   KW  ++R     +  P 
Sbjct: 446 LQLWDTAGQEDYDRLRPLAYPNTDVFMLXFSLMSEASMKNVKVKWYPEIRHHDPHV--PI 273

Query: 119 VLVGTKTDL-----AGRQTVDSAQAQVWALSQGLE---------FFETSVKEMDNYEAPF 164
           VLVGTK DL     A R+   S Q  V + +QG +         +FE S K  +N +  F
Sbjct: 272 VLVGTKLDLRQDKEAVRKLRSSRQDPV-SSNQGNDLAKAIKAKRYFECSSKTQENLKTAF 96
>35581
          Length = 364

 Score = 38.9 bits (89), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 26/101 (25%), Positives = 47/101 (46%)
 Frame = +2

Query: 7   KCILAGDPAVGKTALVQMFRSDGTHFQKNYTLTTGVDLVVKTVPVLDTNDSVELFIFDSA 66
           KC+L GD  VGKT L+    +D        +LTT   L   T   L +     + ++D+A
Sbjct: 50  KCVLLGDAGVGKTCLLNRLATDKFLDSPLTSLTTASLL---TTVTLTSGVMASVDLWDTA 220

Query: 67  GKELFSEMLDKLWENPNVLCLVYDVTNEQSFISCTKWLEKV 107
           G+E +  +    + +   + +VYD  ++   +  T W ++ 
Sbjct: 221 GQERYRSLTSSYYRDTKAVLIVYDAEHK---LKLTDWTDRA 334
>04583
          Length = 1886

 Score = 26.9 bits (58), Expect = 4.7,   Method: Compositional matrix adjust.
 Identities = 12/27 (44%), Positives = 17/27 (62%)
 Frame = -1

Query: 81  NPNVLCLVYDVTNEQSFISCTKWLEKV 107
           +  VLCL Y     Q +ISC+ WLE++
Sbjct: 392 SSTVLCLAYVACQTQLYISCS-WLERL 315
>12231
          Length = 931

 Score = 26.6 bits (57), Expect = 5.6,   Method: Compositional matrix adjust.
 Identities = 16/40 (40%), Positives = 25/40 (62%)
 Frame = +2

Query: 58  VELFIFDSAGKELFSEMLDKLWENPNVLCLVYDVTNEQSF 97
           +ELF+F  AG ELF  +L  L+ N +VL + +  T + +F
Sbjct: 731 MELFVFIHAG*ELFRYVLVLLF-NKHVLAMFWQFTAKYNF 847
>33902
          Length = 671

 Score = 26.6 bits (57), Expect = 7.0,   Method: Compositional matrix adjust.
 Identities = 19/71 (26%), Positives = 35/71 (49%), Gaps = 1/71 (1%)
 Frame = +1

Query: 47  KTVPVLDTNDSVELFIFDSAGKELFSEMLDKLWENPNVLCLVYDVTNEQSF-ISCTKWLE 105
           ++ P L    S +LF+F     EL  +M+  LW+   +    + + ++ S+ +SC     
Sbjct: 112 RSSPQLGYLQSPDLFLFSILESELLIQMMISLWQLLTLPSSSHTLQHKTSWTLSCPSEPY 291

Query: 106 KVRSQTSGISL 116
             +SQ SG+ L
Sbjct: 292 SRQSQISGVLL 324
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|52353955|ref|NP_058662.2| phosphoglycerate
dehydrogenase [Mus musculus]
         (533 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

25533                                                                 203   1e-52
05955                                                                  67   3e-19
20523                                                                  78   7e-15
12358                                                                  45   5e-05
>25533
          Length = 437

 Score =  203 bits (517), Expect = 1e-52,   Method: Composition-based stats.
 Identities = 94/144 (65%), Positives = 111/144 (77%)
 Frame = +2

Query: 119 RQIPQATASMKDGKWDRKKFMGTELNGKTXXXXXXXXXXXEVATRMQSFGMKTVGYDPII 178
           R + +A  SMK+G+WDRK FMG ELNGKT           EVA RMQSFGM T+GYDPII
Sbjct: 2   RDLARAAQSMKEGRWDRKAFMGIELNGKTLAIIGLGRIGREVALRMQSFGMTTIGYDPII 181

Query: 179 SPEVAASFGVQQLPLEEIWPLCDFITVHTPLLPSTTGLLNDSTFAQCKKGVRVVNCARGG 238
             +VAA F  + LPLE+IW   DFITVHTPL+P+TT L+ND+ FA+CKKG+RVVNCARGG
Sbjct: 182 GADVAAEFDTEWLPLEQIWQRADFITVHTPLIPATTNLINDAVFAKCKKGIRVVNCARGG 361

Query: 239 IVDEGALLRALQSGQCAGAALDVF 262
           I++E ALLRAL+SGQC GA LDVF
Sbjct: 362 IIEEAALLRALESGQCGGAGLDVF 433
>05955
          Length = 1009

 Score = 67.0 bits (162), Expect(2) = 3e-19,   Method: Compositional matrix adjust.
 Identities = 34/94 (36%), Positives = 53/94 (56%), Gaps = 1/94 (1%)
 Frame = -3

Query: 160 VATRMQSFGMKTVGYDPIISPEVAASFGVQQL-PLEEIWPLCDFITVHTPLLPSTTGLLN 218
           VA R + FG   + YDP ++  +  S G+ ++  L+E+    D +++H  L      L+N
Sbjct: 284 VAVRAKVFGFNVIFYDPYLADGIEKSLGITRVYTLQELLFQSDCVSLHCTLNEHNHHLIN 105

Query: 219 DSTFAQCKKGVRVVNCARGGIVDEGALLRALQSG 252
           D T  Q + G  ++N ARGG+VDE AL  AL+ G
Sbjct: 104 DYTIKQMRPGAFLINTARGGLVDEHALAVALKDG 3

 Score = 46.2 bits (108), Expect(2) = 3e-19,   Method: Compositional matrix adjust.
 Identities = 29/96 (30%), Positives = 49/96 (51%)
 Frame = -1

Query: 45  LQDCEGLIVRSATKVTADVINAAEKLQVVGRAGTGVDNVDLEAATRKGILVMNTPNGNSL 104
           L +  G ++     +T + ++  + L+V+ R G+G DNVD++AA   GI V N P     
Sbjct: 649 LNEAVGALMWHTITLTKEDLDKFKSLRVIIRIGSGFDNVDVKAAGEMGIAVCNVPGYGVE 470

Query: 105 SAAELTCGMIMCLARQIPQATASMKDGKWDRKKFMG 140
             A+ T  +I+ L R+       +++G    KK MG
Sbjct: 469 EVADSTLCLILNLYRRTYWLANMVREG----KKLMG 374
>20523
          Length = 422

 Score = 78.2 bits (191), Expect = 7e-15,   Method: Composition-based stats.
 Identities = 41/81 (50%), Positives = 55/81 (67%), Gaps = 7/81 (8%)
 Frame = -1

Query: 248 ALQSGQCAGAALDVFTEEPPRD---RALVDHENVISCPHLGASTKEAQSRCGEEIAVQFV 304
           AL+SG+CAGAA DV+ EEPP+    +AL++H  V++ PHLGAST EAQ R   E+A QF+
Sbjct: 419 ALKSGKCAGAAFDVYAEEPPKSEVTKALINHPKVVATPHLGASTSEAQVRVAVEVAEQFI 240

Query: 305 DM----VKGKSLTGVVNAQAL 321
            +     K  S  GV+N +AL
Sbjct: 239 ALNGTSSKYTSYIGVINKEAL 177
>12358
          Length = 598

 Score = 45.4 bits (106), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 27/82 (32%), Positives = 42/82 (51%), Gaps = 1/82 (1%)
 Frame = -2

Query: 236 RGGIVDEGALLRALQSGQCAGAALDVFTEEP-PRDRALVDHENVISCPHLGASTKEAQSR 294
           RGG+++   L  AL++G   GA LDV   EP P    LV   N +  PH+G++T ++++ 
Sbjct: 549 RGGVINHDHLAVALKTGVIGGAGLDVTEPEPLPPTHPLVHLPNCVVTPHMGSNTWDSRNS 370

Query: 295 CGEEIAVQFVDMVKGKSLTGVV 316
                A   V +  G    G+V
Sbjct: 369 MSVTAAQCIVTVFNGGKPMGLV 304
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|13385878|ref|NP_080662.1| sorting nexin 2 [Mus
musculus]
         (519 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

21098                                                                 202   2e-52
01954                                                                  51   1e-06
01097                                                                  50   2e-06
12345                                                                  45   5e-05
07779                                                                  40   0.002
29939                                                                  32   0.46 
>21098
          Length = 518

 Score =  202 bits (515), Expect = 2e-52,   Method: Compositional matrix adjust.
 Identities = 99/167 (59%), Positives = 131/167 (78%)
 Frame = +2

Query: 353 NSEDHTALSRALSQLAEVEEKIDQLHQEQAFADFYMFSELLSDYIRLIAAVKGVFDHRMK 412
           N E+HT LSRALSQLAE EEKI+ +H+ QA  DFY  +ELL DYI LI AVK VF  R+K
Sbjct: 2   NVEEHTTLSRALSQLAETEEKIEGIHKVQADTDFYTMAELLKDYIALIGAVKEVFHERVK 181

Query: 413 CWQKWEDAQITLLKKRETEAKMMVANKPDKIQQAKNEIREWEAKVQQGERDFEQISKTIR 472
            ++ W++A++ L KKRE +AK  V NK DK+ QAK EI EWE K+++G+++F+++SK IR
Sbjct: 182 SYKNWKEAEVMLGKKREAKAKFEVLNKTDKVSQAKQEITEWEGKMEKGQQEFDKLSKVIR 361

Query: 473 KEVGRFEKERVKDFKAVIIKYLESLVQTQQQLIKYWEAFLPEAKAIA 519
           +EV RFE  RV+DFK  +IKYL++L++ QQ+LIKYWE+FL EAKAIA
Sbjct: 362 REVVRFEAYRVEDFKKSVIKYLQTLMENQQKLIKYWESFLLEAKAIA 502
>01954
          Length = 1966

 Score = 51.2 bits (121), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 39/122 (31%), Positives = 62/122 (50%)
 Frame = -3

Query: 142  IEIGVSDPEKVGDGMNAYMAYRVTTKTSLSMFSKSEFSVKRRFSDFLGLHSKLASKYLHV 201
            +EI + DP+  G     Y  Y V  K++L +F   + SV+RR+SDF  L S+L       
Sbjct: 1862 LEIDIVDPQTHGVAKARYTDYEVRMKSNLPVFKLRDSSVRRRYSDFEWLRSELERD---S 1692

Query: 202  GYIVPPAPEKSIVGMTKVKVGKEDSSSTEFVEKRRAALERYLQRTVKHPTLLQDPDLRQF 261
              +VPP P K++      + G +     EF+E+RR  LE+++ +   HP    +  L  F
Sbjct: 1691 KIVVPPLPGKALKRQLPFR-GDDGIFEEEFIEERRKGLEQFINKVAGHPLAQNEKCLHMF 1515

Query: 262  LE 263
            L+
Sbjct: 1514 LQ 1509
>01097
          Length = 2021

 Score = 50.1 bits (118), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 54/198 (27%), Positives = 85/198 (42%), Gaps = 16/198 (8%)
 Frame = +1

Query: 113 IESKSISAPVIFDRSRDEIEEEANGDIFDIEIG------VSDPEKVGDGMN---AYMAYR 163
            + K  S  + FD S ++ E E       +  G      VS  E V DG +     MA R
Sbjct: 76  CQKKEDSPDLAFDESSEDAENEDLTQNVSLNTGTLPLFRVSVTEAVKDGASLQFTIMATR 255

Query: 164 VTTKTSLSMFSKSEFSVKRRFSDFLGLHSKLASKYLHVGYIVPPAPE------KSIVGMT 217
           V     +         V R+F D   LH +L ++   VG I+PP P       KS+   T
Sbjct: 256 VEADRGMV--------VTRQFEDLEWLHHRLMAENDTVGIIIPPLPARPEFDPKSVESKT 411

Query: 218 KVKVGKE-DSSSTEFVEKRRAALERYLQRTVKHPTLLQDPDLRQFLESSELPRAVNTQAL 276
           K ++G + +    +  +    A+++YL   + HPT  +D +L  FL  SE   AV T+  
Sbjct: 412 KKQLGSDCNILRPDDFDLECKAVQKYLSLMLSHPTFGRDKNLETFL--SEKEAAVRTKV- 582

Query: 277 SGAGILRMVNKAADAVNK 294
              G++  ++   D+  K
Sbjct: 583 -SKGLIGWLSTTIDSARK 633
>12345
          Length = 933

 Score = 45.4 bits (106), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 31/117 (26%), Positives = 62/117 (52%)
 Frame = +3

Query: 149 PEKVGDGMNAYMAYRVTTKTSLSMFSKSEFSVKRRFSDFLGLHSKLASKYLHVGYIVPPA 208
           PEK G  +  ++ Y VT++       + + +V RR++DF+ L+  +  ++ +   I+P  
Sbjct: 225 PEKKGLILK-HVEYEVTSQ-------RFKTTVLRRYNDFVALYEMVMMRFPY--RILPKL 374

Query: 209 PEKSIVGMTKVKVGKEDSSSTEFVEKRRAALERYLQRTVKHPTLLQDPDLRQFLESS 265
           P K ++G  +           EF+E+R+ +L+R++    +HP + +D  L+ FL  S
Sbjct: 375 PPKKMLGANR-----------EFIEQRKKSLKRFINIIARHPQINEDKLLKFFLTYS 512
>07779
          Length = 1055

 Score = 40.4 bits (93), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 34/108 (31%), Positives = 48/108 (44%), Gaps = 2/108 (1%)
 Frame = +1

Query: 153 GDGMNAYMAYRVTTKTSLSMFSKSEFSVKRRFSDFLGLHSKLASKYLHVGYIVPPAPEKS 212
           G   + Y  Y+   +         E++V RR+S FL LH++L   Y  V       P K 
Sbjct: 589 GTASDQYHVYQAYVR-----IGDEEWNVFRRYSQFLDLHARLKKVYPIVSKF--DFPSKK 747

Query: 213 IVGMTKVKVGKEDSSSTEFVEKRRAALERYLQRTVKHPTLLQ--DPDL 258
            VG  + KV          VE RR   ++YL+R +    LLQ  +PDL
Sbjct: 748 TVGNKEAKV----------VESRRLVFQQYLRRVI---NLLQEKNPDL 852
>29939
          Length = 998

 Score = 32.3 bits (72), Expect = 0.46,   Method: Compositional matrix adjust.
 Identities = 18/46 (39%), Positives = 26/46 (56%)
 Frame = -2

Query: 467 ISKTIRKEVGRFEKERVKDFKAVIIKYLESLVQTQQQLIKYWEAFL 512
           IS     E+  F+KERVKDFK ++  YL S ++  Q + +  E  L
Sbjct: 655 ISYATLAEMNHFQKERVKDFKIMMQLYLRSQIKFYQDMTQKLEGAL 518
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|170650601|ref|NP_598908.2| LRP16 protein [Mus
musculus]
         (323 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

14529                                                                 201   2e-52
>14529
          Length = 1300

 Score =  201 bits (512), Expect = 2e-52,   Method: Compositional matrix adjust.
 Identities = 98/180 (54%), Positives = 123/180 (68%), Gaps = 2/180 (1%)
 Frame = -3

Query: 145 DKQLNEKISLYRGDITKLEVDAIVNAANSSLLGGGGVDGCIHRAAGSLLTDECRTLQNCE 204
           ++ LN+K+SL RGDIT LE+DAIVNAAN SLLGGGGVDG IH +AG+ L  EC TL+ C+
Sbjct: 899 NENLNKKMSLLRGDITTLEIDAIVNAANGSLLGGGGVDGAIHSSAGNFLKRECSTLKGCD 720

Query: 205 TGKAKITCGYRLPAKYVIHTVGPIAVGQPTASQAAEXXXXXXXXXXXXXXXXXXXVAFPC 264
           TG AKITCGY+LPAK+VIHTVGPI         A                     VAFPC
Sbjct: 719 TGDAKITCGYKLPAKHVIHTVGPI------GEDAKNLHSAYLRSLQVLKENSLKSVAFPC 558

Query: 265 ISTGVFGYPNEEAAEVVLASLREWLEQHK--DKVDRLIICVFLEKDEGIYRERLPHYFPV 322
           ISTG++GYP + AA V L ++R+WLE     ++V+R+I+CVFL+KD  IY + L HYFP+
Sbjct: 557 ISTGIYGYPGQAAAHVALETIRKWLETDAYCEQVERIILCVFLKKDVEIYEDLLHHYFPL 378
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|7657011|ref|NP_056550.1| damage specific DNA binding
protein 1 [Mus musculus]
         (1140 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

22154                                                                 204   2e-52
39177                                                                 179   7e-45
36233                                                                 164   2e-40
08936                                                                  60   4e-09
30373                                                                  32   2.0  
24521                                                                  30   4.6  
>22154
          Length = 382

 Score =  204 bits (519), Expect = 2e-52,   Method: Compositional matrix adjust.
 Identities = 96/127 (75%), Positives = 110/127 (86%)
 Frame = -2

Query: 897  KELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSA 956
            KELR EC+++N+I+ALY+K KGDF+LVGDLMRSV LLAYK  EG  EEIARD NPNWM++
Sbjct: 381  KELRLECSNFNHIIALYVKVKGDFVLVGDLMRSVSLLAYKQREGQLEEIARDCNPNWMTS 202

Query: 957  VEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQN 1016
            VEILDDDNFLGAEN+FNLF CQKDSAA TDEER  +QEVGLFH GEFVNVF  GSLV+Q+
Sbjct: 201  VEILDDDNFLGAENSFNLFTCQKDSAAATDEERSQMQEVGLFHYGEFVNVFKPGSLVIQH 22

Query: 1017 LGEASTP 1023
             GE+ TP
Sbjct: 21   SGESLTP 1
>39177
          Length = 404

 Score =  179 bits (453), Expect = 7e-45,   Method: Compositional matrix adjust.
 Identities = 83/122 (68%), Positives = 100/122 (81%)
 Frame = -3

Query: 1019 EASTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHT 1078
            E+ TP   SVL GT++G +GLV  + + +++ L+D+Q RL  +IKSVGKI+HSFWRSFHT
Sbjct: 396  ESLTPIHNSVLIGTIHGAVGLVAQIPQEFFSFLMDVQKRLANLIKSVGKIDHSFWRSFHT 217

Query: 1079 ERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTR 1138
            ERKTE A GFIDGDLIESFLD+SR KM EVV  LQ DDGSGMKREAT +DL+KVVEELTR
Sbjct: 216  ERKTEAAQGFIDGDLIESFLDLSRDKMFEVVQGLQIDDGSGMKREATVEDLVKVVEELTR 37

Query: 1139 IH 1140
            +H
Sbjct: 36   VH 31
>36233
          Length = 379

 Score =  164 bits (415), Expect = 2e-40,   Method: Compositional matrix adjust.
 Identities = 81/125 (64%), Positives = 98/125 (78%), Gaps = 4/125 (3%)
 Frame = +1

Query: 96  ESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAF 155
           ESI+IITRAHGNVQDRIGRPSETGI+GIIDP+CR IGLRLYDGLFKVIPLD+DNKELKAF
Sbjct: 1   ESIEIITRAHGNVQDRIGRPSETGILGIIDPQCRCIGLRLYDGLFKVIPLDKDNKELKAF 180

Query: 156 NIRLEELHVIDVKFLYGCQAPTICFVYQDP----QGRHVKTYEVSLREKEFNKGPWKQEN 211
           N+R EEL VID++FL+GC  PTI  ++QDP       H++ +     + +  K P +Q N
Sbjct: 181 NVRFEELTVIDIQFLHGCSYPTIALIHQDPPKAVMSEHMRFH---CGKGD*PKSP*EQNN 351

Query: 212 VEAEA 216
           VE E+
Sbjct: 352 VETES 366
>08936
          Length = 1098

 Score = 60.5 bits (145), Expect = 4e-09,   Method: Compositional matrix adjust.
 Identities = 62/255 (24%), Positives = 109/255 (42%), Gaps = 22/255 (8%)
 Frame = +3

Query: 881  LASINSTVRLYEWTTEKELRT-ECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPME 939
            L  +   +R+Y+   +K LR  E  H  N +   + T G  ++VGD+  S   + Y+  E
Sbjct: 3    LIGVGRFLRIYDLGKKKLLRKCENKHIPNFVTT-IHTLGHRVVVGDIQDSFHFVRYRRQE 179

Query: 940  GNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQ--KDSAATTDEE--------- 988
                  A D  P W++   +LD +   GA+   N+ V +   + +   DE+         
Sbjct: 180  NQLIVFADDTTPRWITCSTLLDFNTVAGADKFGNINVIRLPPEVSDEVDEDPTGNKALWD 359

Query: 989  -------RQHLQEVGLFHLGEFVNVFCHGSLVMQNLGEASTPTQGS--VLFGTVNGMIG- 1038
                    Q ++ V  FH+GE V+          +L +A+    GS  +++ T++G IG 
Sbjct: 360  RGVLSGASQKVETVASFHIGELVS----------SLQKATLIPGGSEALVYTTLSGGIGM 509

Query: 1039 LVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFL 1098
            LV   S   ++    ++  +     S+   +H  +RS++      P    IDGDL E F 
Sbjct: 510  LVPFTSHDDHDFFQHLEMYMRSEFPSICGRDHLAYRSYYF-----PLKNVIDGDLCEMFN 674

Query: 1099 DISRPKMQEVVANLQ 1113
             +   K + V   L+
Sbjct: 675  SMDNAKQRSVAEELE 719
>30373
          Length = 962

 Score = 31.6 bits (70), Expect = 2.0,   Method: Compositional matrix adjust.
 Identities = 18/66 (27%), Positives = 34/66 (51%)
 Frame = +2

Query: 270 RYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLG 329
           R +L    G L++L L     +DG   ++    +    + +  C+  + N  +F+GSRLG
Sbjct: 179 RCVLSLKGGELYVLTL----VVDGMRCVRGFHFDKAASSVLTSCMCVVPNDFLFLGSRLG 346

Query: 330 DSQLVK 335
           +S L++
Sbjct: 347 NSLLLR 364
>24521
          Length = 1532

 Score = 30.4 bits (67), Expect = 4.6,   Method: Composition-based stats.
 Identities = 16/52 (30%), Positives = 25/52 (48%)
 Frame = +1

Query: 857 KLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNN 908
           +++T  EK  +  VY     +GKL     + + L+ W T   LR   N+Y N
Sbjct: 109 QIKTKQEKSDRKTVY*THLNDGKLFRCNKTIMSLFTWLTSNLLRFNTNYYKN 264
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|34368584|ref|NP_081210.2| erythropoietin 4 immediate
early response [Mus musculus]
         (426 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

36407                                                                 201   3e-52
34506                                                                  42   4e-08
22375                                                                  38   0.010
09448                                                                  32   0.34 
03097                                                                  30   2.2  
00486                                                                  30   2.5  
09520                                                                  29   4.3  
00391                                                                  28   9.1  
>36407
          Length = 1085

 Score =  201 bits (512), Expect = 3e-52,   Method: Compositional matrix adjust.
 Identities = 103/209 (49%), Positives = 128/209 (61%), Gaps = 2/209 (0%)
 Frame = +2

Query: 91  AQKISKGADPKSVVCAFFKQGQCTKGDKCKFSHDLTLERKCEKRSVYIDARDEELEKDTM 150
            Q ++KG DPKSV+CAFFKQGQCTKGDKCKFSHDLT+ERK EK          ++   TM
Sbjct: 65  VQTVTKGTDPKSVLCAFFKQGQCTKGDKCKFSHDLTIERKSEKEVSM------KMSVQTM 226

Query: 151 DNWDE--KKLEEVVNXXXXXXXXXXXXTQIVCRHFLEAIENNKYGWFWVCPGGGDNCMYR 208
             W     K    ++             +  C+HFLEA+EN+KYGWFW CP  GD C+YR
Sbjct: 227 TTWPTGMSKSSMKLSTRNTENLRRPNQNRHYCKHFLEALENSKYGWFWSCP-NGDKCIYR 403

Query: 209 HALPPGFVXXXXXXXXXXXXXXXXXXXXXRERSALGPNVTKITLESFLAWKKRKRQEKID 268
           HALPPGFV                     RER++LG NVTKITLE+FLAWK+RKR+EKID
Sbjct: 404 HALPPGFVLKKDQKKEEKEDQISLEDLIERERASLGCNVTKITLETFLAWKQRKRKEKID 583

Query: 269 KLEQDMERRKADFKAGKALVISGREVFEF 297
            ++ + +++KADFKAG+    SG     F
Sbjct: 584 AMKAEQDKKKADFKAGQFWWFSGATRLWF 670

 Score =  105 bits (263), Expect = 3e-23,   Method: Compositional matrix adjust.
 Identities = 59/104 (56%), Positives = 65/104 (62%), Gaps = 1/104 (0%)
 Frame = +2

Query: 28  TFGLKNKKGAKQQKFIKAVTHQVKFGQQNPRQVAQS-EAXXXXXXXXXXXXXXXXXXXXX 86
           TFGLKNKKG KQQKFIK VT QVK G Q   ++ Q                         
Sbjct: 779 TFGLKNKKGTKQQKFIKTVTQQVKQGNQKASKLDQMLRDEREKKKEEKKKMQDELNTLFR 958

Query: 87  PVVAAQKISKGADPKSVVCAFFKQGQCTKGDKCKFSHDLTLERK 130
           PV   Q ++KG DPKSV+CAFFKQGQCTKGDKCKFSHDLT+ERK
Sbjct: 959 PV---QTVTKGTDPKSVLCAFFKQGQCTKGDKCKFSHDLTIERK 1081
>34506
          Length = 420

 Score = 42.0 bits (97), Expect(2) = 4e-08,   Method: Compositional matrix adjust.
 Identities = 19/36 (52%), Positives = 26/36 (72%)
 Frame = +3

Query: 269 KLEQDMERRKADFKAGKALVISGREVFEFRPELVND 304
           KL  + ER+K+D+  GK   ISGRE+F F P+LV+D
Sbjct: 51  KLVAEEERKKSDYSKGKQFGISGREMFSFNPDLVDD 158

 Score = 33.5 bits (75), Expect(2) = 4e-08,   Method: Composition-based stats.
 Identities = 14/15 (93%), Positives = 14/15 (93%)
 Frame = +1

Query: 252 LESFLAWKKRKRQEK 266
           LESFLAWKKRK QEK
Sbjct: 1   LESFLAWKKRKLQEK 45
>22375
          Length = 1114

 Score = 37.7 bits (86), Expect = 0.010,   Method: Compositional matrix adjust.
 Identities = 42/131 (32%), Positives = 65/131 (49%), Gaps = 8/131 (6%)
 Frame = +3

Query: 287 LVISGREVFEFRPELVNDDDEEADDTRYIQGTGGDEVDDSMGVNDIDISLYVPRDVE-ET 345
           L ISGR++FEF PELV  DD++  D          E ++S  V +I +  ++ +  E +T
Sbjct: 6   LGISGRQMFEFNPELVTGDDDDDADDGVFMQREEGEDEESGTVKEISLDYFMEQASEVDT 185

Query: 346 GITVASVERFSTYAPDKDENKLSEAS--GGLAENGERSDLDEDSGGG----GQENGSIDA 399
             T AS  R   + P  +  KL EA+      +   ++ +D D+          NG I A
Sbjct: 186 SGTQASARR---WQPSDEAGKLDEAAAIASPVDPATQAQIDTDAAIAMAVSATVNGEIAA 356

Query: 400 -VPVDENLFTG 409
            +P+DE+LF G
Sbjct: 357 DMPIDEDLFAG 389
>09448
          Length = 1546

 Score = 32.3 bits (72), Expect = 0.34,   Method: Compositional matrix adjust.
 Identities = 14/32 (43%), Positives = 19/32 (59%)
 Frame = +3

Query: 95  SKGADPKSVVCAFFKQGQCTKGDKCKFSHDLT 126
           S G   K +   F + G+C++GDKC F HD T
Sbjct: 588 STGQGTKKICLYFSRFGKCSRGDKCPFLHDPT 683
>03097
          Length = 1401

 Score = 29.6 bits (65), Expect = 2.2,   Method: Compositional matrix adjust.
 Identities = 14/51 (27%), Positives = 27/51 (52%)
 Frame = +1

Query: 87  PVVAAQKISKGADPKSVVCAFFKQGQCTKGDKCKFSHDLTLERKCEKRSVY 137
           P+ A  +++   D +   C  ++ G+CT+G  C F H   + R+  +R +Y
Sbjct: 325 PIYA--ELTPVTDFREACCRQYEMGECTRGGFCNFMHLKPISREL-RRELY 468
>00486
          Length = 797

 Score = 29.6 bits (65), Expect = 2.5,   Method: Compositional matrix adjust.
 Identities = 15/48 (31%), Positives = 26/48 (54%)
 Frame = -2

Query: 286 ALVISGREVFEFRPELVNDDDEEADDTRYIQGTGGDEVDDSMGVNDID 333
           AL+   R    FRP + +D+D    DT++ + T  D  DD++  + I+
Sbjct: 463 ALLALRRAEPPFRPNVTSDEDTSQFDTKFTRQTPVDSPDDTILSDSIN 320
>09520
          Length = 1058

 Score = 28.9 bits (63), Expect = 4.3,   Method: Compositional matrix adjust.
 Identities = 15/35 (42%), Positives = 25/35 (71%), Gaps = 3/35 (8%)
 Frame = +1

Query: 248 TKITLESFLAWKKR---KRQEKIDKLEQDMERRKA 279
           T++T+ESF+AWK +   +R+E+  +LE+D E  K 
Sbjct: 580 TRVTIESFMAWKTKFDAERKER-KRLEKDSELSKT 681
>00391
          Length = 1202

 Score = 27.7 bits (60), Expect = 9.1,   Method: Compositional matrix adjust.
 Identities = 14/42 (33%), Positives = 21/42 (50%), Gaps = 1/42 (2%)
 Frame = +1

Query: 101 KSVVCAFFKQ-GQCTKGDKCKFSHDLTLERKCEKRSVYIDAR 141
           K+ +C  F++ G C  GDKC+F+H     R   +   Y   R
Sbjct: 691 KTELCRPFEESGHCKYGDKCQFAHGFHELRNLSRHPKYKTER 816
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6679421|ref|NP_032924.1| cytochrome P450 reductase
[Mus musculus]
         (678 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

11856                                                                 202   3e-52
08583                                                                  34   0.19 
20389                                                                  29   6.7  
>11856
          Length = 1298

 Score =  202 bits (514), Expect = 3e-52,   Method: Compositional matrix adjust.
 Identities = 118/363 (32%), Positives = 186/363 (51%), Gaps = 2/363 (0%)
 Frame = -2

Query: 318  DHVAVYPANDSTLVNQIGEILGADLDVIMSLNNLDEESNKKHPFPCPTTYRTALTYYLDI 377
            D V + P N    V Q    +  +      L   D E+        P T    +  YLDI
Sbjct: 1297 DVVMIPPQNSEERVQQFLSHMSFNPTQYFYLQQNDGEAPVPSMLSQPCTIEEVVRCYLDI 1118

Query: 378  TNPPRTNVLYELAQYASEPSEQEHLHKMASSSGEGKELYLSWVVEARRHILAILQDY--P 435
             + PR +    LA +A + +E+E L +  +   EG++   S+    RR IL +LQD+   
Sbjct: 1117 GSVPRRSFFEILAHFADDETEREKLKEFCTP--EGQDDLFSYCNRVRRTILEVLQDFHLT 944

Query: 436  SLRPPIDHLCELLPRLQARYYSIASSSKVHPNSVHICAVAVEYEAKSGRVNKGVATSWLR 495
            S R P+D+L +L+P +Q R +SIASS + HPN +H+    V+Y  K     +GV ++WL 
Sbjct: 943  SQRVPVDYLFDLIPAMQPRAFSIASSPQAHPNEIHMLMAVVKYRTKLHAPRQGVCSTWLA 764

Query: 496  TKEPAGENGRRALVPMFVRKSQFRLPFKPTTPVIMVGPGTGVAPFMGFIQERAWLREQGK 555
            T  P         V ++V+      P  P+ P IMVGPGTGV PF  +I E+A       
Sbjct: 763  TLTPDPS----VKVAVWVKAGTISFPKDPSVPSIMVGPGTGVTPFRSYIHEKA-----AS 611

Query: 556  EVGETLLYYGCRRSDEDYLYREELARFHKDGALTQLNVAFSREQAHKVYVQHLLKRDKEH 615
             +G + L++GCR   +D+   +E     ++  LT    AFSR+Q  K+YVQ  +K + E 
Sbjct: 610  GMGGSYLFFGCRGEHKDFYCSKEWQVLAQNNLLT-FFTAFSRDQEEKIYVQDRIKENGEL 434

Query: 616  LWKLIHEGGAHIYVCGDARNMAKDVQNTFYDIVAEFGPMEHTQAVDYVKKLMTKGRYSLD 675
            LW+L++E  A++++ G+A+ M  DV+     ++ E G    T+A  +++ L    R+ L+
Sbjct: 433  LWRLLNEESAYVFIAGNAKRMPDDVRAVMRAVIQEQGNQSETEAETFLQSLERNRRWQLE 254

Query: 676  VWS 678
             WS
Sbjct: 253  AWS 245
>08583
          Length = 1276

 Score = 34.3 bits (77), Expect = 0.19,   Method: Compositional matrix adjust.
 Identities = 19/65 (29%), Positives = 31/65 (47%), Gaps = 3/65 (4%)
 Frame = +3

Query: 384 NVLYELAQYASEP--SEQEHLHKMASSSGEGKELYLS-WVVEARRHILAILQDYPSLRPP 440
           N+ +    Y   P  S+Q        + G  K  +LS W++ A  H++   QD+P   PP
Sbjct: 372 NIDFHDCVYGGLPLASDQRSSSPKGQTCGSFKVPFLSVWLIRALAHLVGT*QDFPGRGPP 551

Query: 441 IDHLC 445
           + +LC
Sbjct: 552 LTNLC 566
>20389
          Length = 975

 Score = 28.9 bits (63), Expect = 6.7,   Method: Compositional matrix adjust.
 Identities = 16/39 (41%), Positives = 24/39 (61%), Gaps = 4/39 (10%)
 Frame = -2

Query: 397 SEQEHLHKMASSSGEGKELYLS----WVVEARRHILAIL 431
           +EQ H H+ +S   EG+E+ L+    W V +RR  +AIL
Sbjct: 704 TEQGHAHRFSSELREGREITLALQPKWRV*SRRFWIAIL 588
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|159110817|ref|NP_077785.2| abhydrolase domain
containing 12 [Mus musculus]
         (398 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

03845                                                                 201   4e-52
26582                                                                 116   9e-40
13372                                                                  65   6e-23
11264                                                                  42   5e-04
36640                                                                  30   2.0  
>03845
          Length = 1326

 Score =  201 bits (512), Expect = 4e-52,   Method: Compositional matrix adjust.
 Identities = 100/289 (34%), Positives = 154/289 (53%)
 Frame = +2

Query: 110 YFIDLKKPQDQGLNHTCNYYLQPEDDVTIGVWHTIPSVWWKNAQGKDQMWYEDALASNHA 169
           +  +LK P   GL    +  +  +   T+G+WH +P    +         +E  LAS   
Sbjct: 80  FLDNLKDPSASGLEAARHVAIXTDTGHTLGLWHILPESALEEKGVIQDQEFESRLASGTP 259

Query: 170 IILYLHGNAGTRGGDHRVELYKVLSSLGYHVVTFDYRGWGDSVGTPSERGMTYDALHVFD 229
           I +Y HG+ G+R    RV  Y  L    +HVVTFDYRG+GDS G  +E  M  D + VF 
Sbjct: 260 IFIYAHGSGGSRSQFTRVYTYTALRGQEFHVVTFDYRGFGDSTGEATESHMVEDLVTVFR 439

Query: 230 WIKARSGDNPVYIWGHSLGTGVATNLVRRLCERETPPDALILESPFTNIREEAKSHPFSV 289
           W+K R+  +PV++WGHSLG GV T   R L  +   PD ++LE  F N+ +        +
Sbjct: 440 WVKKRAWKSPVFLWGHSLGGGVVTQAARYLSTQNELPDGIVLEGAFNNLHDIVDVALIML 619

Query: 290 IYRYFPGFDWFFLDPITSSGIKFANDENMKHISCPLLILHAEDDPVVPFHLGRKLYNIAA 349
            YR FP     F D + S    FA+D+++ H+ CP L+LHAEDD +VP  LG+KL+    
Sbjct: 620 PYRPFPFLMXIFQDALKSQSAIFASDQHLIHVRCPTLMLHAEDDKIVPIDLGKKLFQSVV 799

Query: 350 PSRSFRDFKVQFIPFHSDLGYRHKYIYKSPELPRILREFLGKSEPERQH 398
            ++     K+    F +D GY H  + ++P+L  ++++F+  S+  ++ 
Sbjct: 800 SAKKTDQAKITMHVFPADKGYGHNRVNQAPDLGSVIKQFVQDSQTHKKQ 946
>26582
          Length = 548

 Score =  116 bits (290), Expect(2) = 9e-40,   Method: Compositional matrix adjust.
 Identities = 53/107 (49%), Positives = 71/107 (66%)
 Frame = +3

Query: 160 YEDALASNHAIILYLHGNAGTRGGDHRVELYKVLSSLGYHVVTFDYRGWGDSVGTPSERG 219
           +E+ L S   I LYLHGN+G RG  HRV++YK +S L  HVV  DYRG+ DS G+PSE G
Sbjct: 15  FEETLPSAKHIFLYLHGNSGHRGAYHRVQMYKFMSRLDAHVVAVDYRGFADSTGSPSEEG 194

Query: 220 MTYDALHVFDWIKARSGDNPVYIWGHSLGTGVATNLVRRLCERETPP 266
           +  DA   + W+K +SG  P+ +WGHSLGTG++T L +    +  PP
Sbjct: 195 VVRDAHFTYKWLKEKSGGXPIVVWGHSLGTGISTILTKSXVMKVMPP 335

 Score = 65.5 bits (158), Expect(2) = 9e-40,   Method: Compositional matrix adjust.
 Identities = 29/72 (40%), Positives = 44/72 (61%)
 Frame = +1

Query: 266 PDALILESPFTNIREEAKSHPFSVIYRYFPGFDWFFLDPITSSGIKFANDENMKHISCPL 325
           P  L+LESPF NI + A  HPF+  +   PGF  F  D      ++F +D+ ++ ++ P+
Sbjct: 331 PQGLVLESPFNNIVDAAVEHPFAFPFANIPGFKSFLRDSAAEHNVRFNSDQLIRGVTSPI 510

Query: 326 LILHAEDDPVVP 337
           LILHA+ D +VP
Sbjct: 511 LILHAKXDSIVP 546
>13372
          Length = 468

 Score = 65.5 bits (158), Expect(2) = 6e-23,   Method: Compositional matrix adjust.
 Identities = 26/78 (33%), Positives = 47/78 (60%)
 Frame = +1

Query: 320 HISCPLLILHAEDDPVVPFHLGRKLYNIAAPSRSFRDFKVQFIPFHSDLGYRHKYIYKSP 379
           H+ CP L+LHAEDD +VP  LG+KL+     ++     K+    F +D GY H  + ++P
Sbjct: 223 HVRCPTLMLHAEDDKIVPIDLGKKLFQSVVSAKKTDQAKITMHVFPADKGYGHNRVNQAP 402

Query: 380 ELPRILREFLGKSEPERQ 397
           +L  ++++F+  S+  ++
Sbjct: 403 DLGSVIKQFVQDSQTHKK 456

 Score = 59.7 bits (143), Expect(2) = 6e-23,   Method: Compositional matrix adjust.
 Identities = 25/61 (40%), Positives = 36/61 (59%)
 Frame = +3

Query: 220 MTYDALHVFDWIKARSGDNPVYIWGHSLGTGVATNLVRRLCERETPPDALILESPFTNIR 279
           M  D + VF W+K R+  +PV++WGHSLG GV T     L  +   PD ++LE  F N+ 
Sbjct: 6   MVEDLVTVFRWVKKRAWKSPVFLWGHSLGGGVVTQAAXYLSTQNELPDGIVLEGAFNNLH 185

Query: 280 E 280
           +
Sbjct: 186 D 188
>11264
          Length = 451

 Score = 42.0 bits (97), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 36/137 (26%), Positives = 59/137 (43%), Gaps = 4/137 (2%)
 Frame = +2

Query: 214 TPSERGMTYDALHVFDWIKARS--GDNPVYIWGHSLGTGVATNLVRRLCERETPPDALIL 271
            PSERG+  DA    D++  R     + + ++G SLG  V  ++       +    A ++
Sbjct: 2   VPSERGLLSDARAAIDYLHTRHDLDHSQLILFGRSLGGAVVIDVAADTVYGQKIMCA-VV 178

Query: 272 ESPFTNIREEAKS--HPFSVIYRYFPGFDWFFLDPITSSGIKFANDENMKHISCPLLILH 329
           E+ FT+IR+ A    HP     +Y P   +           K+ +   +   S P L + 
Sbjct: 179 ENTFTSIRDMAVELVHP---TVKYIPNLLY---------KNKYQSLNKISKCSVPFLFIS 322

Query: 330 AEDDPVVPFHLGRKLYN 346
              D +VP H+ R LY 
Sbjct: 323 GLADNLVPPHMMRALYT 373
>36640
          Length = 419

 Score = 29.6 bits (65), Expect = 2.0,   Method: Compositional matrix adjust.
 Identities = 12/32 (37%), Positives = 19/32 (59%)
 Frame = +1

Query: 297 FDWFFLDPITSSGIKFANDENMKHISCPLLIL 328
           +++ FL  +TS  + F+  E  K  +CP LIL
Sbjct: 73  YNFIFLRAVTSINVSFSESEREKE*ACPPLIL 168
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|29789080|ref|NP_056642.1| coatomer protein complex,
subunit beta 2 (beta prime) [Mus musculus]
         (905 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

29585                                                                 202   5e-52
30256                                                                  95   1e-19
17598                                                                  87   2e-17
12806                                                                  87   4e-17
27465                                                                  83   6e-16
19949                                                                  79   1e-14
00561                                                                  76   5e-14
12574                                                                  74   3e-13
02147                                                                  68   2e-11
03395                                                                  64   2e-10
18981                                                                  64   3e-10
01768                                                                  63   4e-10
26939                                                                  62   9e-10
01327                                                                  62   1e-09
13335                                                                  61   2e-09
03156                                                                  59   7e-09
37180                                                                  57   3e-08
03387                                                                  57   5e-08
31474                                                                  55   2e-07
17602                                                                  50   2e-07
14555                                                                  42   3e-07
02090                                                                  52   8e-07
12960                                                                  52   1e-06
02960                                                                  51   2e-06
17266                                                                  49   8e-06
11493                                                                  49   1e-05
21105                                                                  47   4e-05
15337                                                                  45   1e-04
13278                                                                  45   1e-04
16105                                                                  43   5e-04
01805                                                                  43   5e-04
21960                                                                  43   7e-04
27806                                                                  42   8e-04
10162                                                                  42   9e-04
26107                                                                  41   0.002
19863                                                                  41   0.002
27270                                                                  40   0.003
08679                                                                  40   0.003
01462                                                                  40   0.005
01249                                                                  39   0.010
19498                                                                  38   0.014
20662                                                                  38   0.016
38177                                                                  38   0.019
04524                                                                  38   0.022
20271                                                                  38   0.022
06576                                                                  37   0.029
21921                                                                  37   0.043
03044                                                                  37   0.045
19140                                                                  37   0.052
33180                                                                  36   0.053
16199                                                                  35   0.096
04358                                                                  35   0.099
17298                                                                  35   0.10 
15745                                                                  35   0.11 
15972                                                                  35   0.13 
31054                                                                  35   0.14 
05393                                                                  35   0.15 
10264                                                                  35   0.19 
01598                                                                  35   0.19 
15118                                                                  34   0.21 
12140                                                                  34   0.29 
12841                                                                  33   0.39 
29912                                                                  33   0.42 
21763                                                                  33   0.43 
25526                                                                  33   0.51 
30297                                                                  33   0.58 
07151                                                                  33   0.59 
34005                                                                  33   0.73 
25400                                                                  32   0.78 
25470                                                                  32   0.87 
04395                                                                  32   1.2  
27475                                                                  32   1.3  
14500                                                                  31   1.7  
30295                                                                  31   1.8  
04088                                                                  31   2.0  
31118                                                                  31   2.4  
05303                                                                  31   2.5  
06253                                                                  31   2.9  
25880                                                                  30   3.1  
27681                                                                  30   3.8  
31864                                                                  30   3.8  
31384                                                                  30   4.0  
05642                                                                  30   6.0  
>29585
          Length = 366

 Score =  202 bits (514), Expect = 5e-52,   Method: Compositional matrix adjust.
 Identities = 95/120 (79%), Positives = 109/120 (90%)
 Frame = -2

Query: 438 LLGVRSVNGLAFYDWENTELIRRIEIQPKHIFWSDSGELVCIATEESFFILKYLSEKVLA 497
           +LGVRSV+GLAFYDWE TEL+RRIEI PK+IFWS++GELVCIATEESFF+LKY +E V  
Sbjct: 362 MLGVRSVSGLAFYDWETTELVRRIEITPKNIFWSENGELVCIATEESFFVLKYSAEAVEQ 183

Query: 498 AQETHEGVTEDGIEDAFEVLGEIQEIVKTGLWVGDCFIYTSSVNRLNYYVGGEIVTIAHL 557
           A++  E VTEDGIEDAFEVL E++E V+TGLWVGDCFIYT+SVNRLNYYVGGEIVTIAHL
Sbjct: 182 AKDDKEKVTEDGIEDAFEVLTEVEESVRTGLWVGDCFIYTNSVNRLNYYVGGEIVTIAHL 3
>30256
          Length = 961

 Score = 95.1 bits (235), Expect = 1e-19,   Method: Compositional matrix adjust.
 Identities = 64/223 (28%), Positives = 107/223 (47%), Gaps = 3/223 (1%)
 Frame = +3

Query: 41  VWNHETQTLVKTFEVCDLPVRAAKFVARKNWVVTGADDMQIRVFNYNTLERVHMFEAHSD 100
           VWN +T     T       VR      +K  VV+G+ D  +RV++  +   +++   H  
Sbjct: 114 VWNADTGVCTHTLYGHSSTVRCLSLSGKK--VVSGSRDATLRVWDIESGHCLNVLLGHMA 287

Query: 101 YIRCIAVHPTQPFILTSSDDMLIKLWDWDKKWSCSQVFEGHTHYVMQIVINPKDNNQFAS 160
            +RC+     +  +++ + D  +++WD D   SC    +GHT+ V  +     D     S
Sbjct: 288 AVRCVQYDGKR--VVSGAXDYTVRVWDPDTA-SCLHTLQGHTNRVYSLQF---DGVYVVS 449

Query: 161 ASLDRTIKVWQLGSSSPNFTLEGHEKGVNCIDYYSGGDKPYLISGADDRLVKIWDYQNKT 220
            SLD +I+VW +       TL GH+   + ++         L+SG  D  VK+WD     
Sbjct: 450 GSLDTSIRVWDVRCGKLVHTLMGHQSLTSGLEL----KDNLLVSGNADSTVKVWDVHTGK 617

Query: 221 CVQTLEG---HAQNVSCASFHPELPIIITGSEDGTVRIWHSST 260
           C+QTL G   H   V+C  F+ +   ++T S+DGTV++W  +T
Sbjct: 618 CLQTLLGPNKHRSAVTCLQFNKKF--VVTCSDDGTVKLWDLNT 740

 Score = 78.6 bits (192), Expect = 1e-14,   Method: Compositional matrix adjust.
 Identities = 47/158 (29%), Positives = 78/158 (49%)
 Frame = +3

Query: 110 TQPFILTSSDDMLIKLWDWDKKWSCSQVFEGHTHYVMQIVINPKDNNQFASASLDRTIKV 169
           T   +++ S D  +K+W+ D    C+    GH+  V  + ++ K   +  S S D T++V
Sbjct: 69  TGNTVISGSTDRSLKVWNADTG-VCTHTLYGHSSTVRCLSLSGK---KVVSGSRDATLRV 236

Query: 170 WQLGSSSPNFTLEGHEKGVNCIDYYSGGDKPYLISGADDRLVKIWDYQNKTCVQTLEGHA 229
           W + S      L GH   V C+ Y    D   ++SGA D  V++WD    +C+ TL+GH 
Sbjct: 237 WDIESGHCLNVLLGHMAAVRCVQY----DGKRVVSGAXDYTVRVWDPDTASCLHTLQGHT 404

Query: 230 QNVSCASFHPELPIIITGSEDGTVRIWHSSTYRLESTL 267
             V   S   +   +++GS D ++R+W     +L  TL
Sbjct: 405 NRV--YSLQFDGVYVVSGSLDTSIRVWDVRCGKLVHTL 512

 Score = 67.0 bits (162), Expect = 4e-11,   Method: Compositional matrix adjust.
 Identities = 43/142 (30%), Positives = 66/142 (46%)
 Frame = +3

Query: 134 CSQVFEGHTHYVMQIVINPKDNNQFASASLDRTIKVWQLGSSSPNFTLEGHEKGVNCIDY 193
           C +   GHT  V     +    N   S S DR++KVW   +     TL GH   V C+  
Sbjct: 18  CIKNLIGHTGGVWS---SQMTGNTVISGSTDRSLKVWNADTGVCTHTLYGHSSTVRCLSL 188

Query: 194 YSGGDKPYLISGADDRLVKIWDYQNKTCVQTLEGHAQNVSCASFHPELPIIITGSEDGTV 253
              G K  ++SG+ D  +++WD ++  C+  L GH   V C  +  +   +++G+ D TV
Sbjct: 189 --SGKK--VVSGSRDATLRVWDIESGHCLNVLLGHMAAVRCVQYDGKR--VVSGAXDYTV 350

Query: 254 RIWHSSTYRLESTLNYGMERVW 275
           R+W   T     TL     RV+
Sbjct: 351 RVWDPDTASCLHTLQGHTNRVY 416

 Score = 60.5 bits (145), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 48/191 (25%), Positives = 91/191 (47%), Gaps = 6/191 (3%)
 Frame = +3

Query: 41  VWNHETQTLVKTFEVCDLPVRAAKFVARKNWVVTGADDMQIRVFNYNTLERVHMFEAHSD 100
           VW+ E+   +         VR  ++  ++  VV+GA D  +RV++ +T   +H  + H++
Sbjct: 234 VWDIESGHCLNVLLGHMAAVRCVQYDGKR--VVSGAXDYTVRVWDPDTASCLHTLQGHTN 407

Query: 101 YIRCIAVHPTQPFILTSSDDMLIKLWDWDKKWSCSQVFEGHT---HYVMQIVINPKDNNQ 157
             R  ++     ++++ S D  I++WD      C ++   HT   H  +   +  KDN  
Sbjct: 408 --RVYSLQFDGVYVVSGSLDTSIRVWDV----RCGKLV--HTLMGHQSLTSGLELKDN-L 560

Query: 158 FASASLDRTIKVWQLGSSSPNFTLEG---HEKGVNCIDYYSGGDKPYLISGADDRLVKIW 214
             S + D T+KVW + +     TL G   H   V C+ +    +K ++++ +DD  VK+W
Sbjct: 561 LVSGNADSTVKVWDVHTGKCLQTLLGPNKHRSAVTCLQF----NKKFVVTCSDDGTVKLW 728

Query: 215 DYQNKTCVQTL 225
           D      ++ L
Sbjct: 729 DLNTGDFIRNL 761

 Score = 52.4 bits (124), Expect = 9e-07,   Method: Compositional matrix adjust.
 Identities = 32/97 (32%), Positives = 47/97 (48%)
 Frame = +3

Query: 181 LEGHEKGVNCIDYYSGGDKPYLISGADDRLVKIWDYQNKTCVQTLEGHAQNVSCASFHPE 240
           L GH  GV    + S      +ISG+ DR +K+W+     C  TL GH+  V C S   +
Sbjct: 30  LIGHTGGV----WSSQMTGNTVISGSTDRSLKVWNADTGVCTHTLYGHSSTVRCLSLSGK 197

Query: 241 LPIIITGSEDGTVRIWHSSTYRLESTLNYGMERVWCV 277
              +++GS D T+R+W   +    + L   M  V CV
Sbjct: 198 K--VVSGSRDATLRVWDIESGHCLNVLLGHMAAVRCV 302
>17598
          Length = 875

 Score = 87.4 bits (215), Expect = 2e-17,   Method: Compositional matrix adjust.
 Identities = 44/164 (26%), Positives = 82/164 (50%), Gaps = 1/164 (0%)
 Frame = +1

Query: 95  FEAHSDYIRCIAVHPTQPFILTSSDDMLIKLWDWDKKWSCSQVFEGHTHYVMQIVINPKD 154
            + HS ++  +++     ++L+SS D  ++LWD  KK + ++ F  HT   + +  +P D
Sbjct: 109 LQGHSHFVSDVSLSADSRYVLSSSWDATLRLWD-IKKGNTTRRFISHTRDALAVAFSP-D 282

Query: 155 NNQFASASLDRTIKVWQ-LGSSSPNFTLEGHEKGVNCIDYYSGGDKPYLISGADDRLVKI 213
           N Q AS   D+ +K+W  +G          H+  V C+ ++     P ++S + D+ +K+
Sbjct: 283 NRQIASGGRDKALKIWNTVGECKFTVDANSHQDWVTCVKFHQDAKSPLVVSASMDKTIKV 462

Query: 214 WDYQNKTCVQTLEGHAQNVSCASFHPELPIIITGSEDGTVRIWH 257
           WD Q  T   T  GH   ++      +   + +GS+DG V  W+
Sbjct: 463 WDNQTMTLKHTFVGHKTQINAIDLALKTYYLASGSKDGIVMTWN 594

 Score = 36.6 bits (83), Expect = 0.050,   Method: Compositional matrix adjust.
 Identities = 21/68 (30%), Positives = 37/68 (54%), Gaps = 10/68 (14%)
 Frame = +1

Query: 199 KPYLISGADDRLVKIWDY-------QNKTC---VQTLEGHAQNVSCASFHPELPIIITGS 248
           K +LI G  D+L+ +WD        +++T     +TL+GH+  VS  S   +   +++ S
Sbjct: 1   KEFLIXGGRDKLLIVWDLVPRKDGDEDETWGGPRRTLQGHSHFVSDVSLSADSRYVLSSS 180

Query: 249 EDGTVRIW 256
            D T+R+W
Sbjct: 181 WDATLRLW 204

 Score = 32.7 bits (73), Expect = 0.62,   Method: Compositional matrix adjust.
 Identities = 17/72 (23%), Positives = 31/72 (43%)
 Frame = +1

Query: 5   LDIKRKLTARSDRVKSVDLHPTEPWMLASLYNGSVCVWNHETQTLVKTFEVCDLPVRAAK 64
           + +K        ++ ++DL     ++ +   +G V  WN +  T +   + CD  V A K
Sbjct: 478 MTLKHTFVGHKTQINAIDLALKTYYLASGSKDGIVMTWNIQNGTFLGKID-CDCEVNAVK 654

Query: 65  FVARKNWVVTGA 76
           F   K W+  G 
Sbjct: 655 FSPNKYWLFVGT 690
>12806
          Length = 961

 Score = 86.7 bits (213), Expect = 4e-17,   Method: Compositional matrix adjust.
 Identities = 47/164 (28%), Positives = 78/164 (47%), Gaps = 1/164 (0%)
 Frame = +3

Query: 95  FEAHSDYIRCIAVHPTQPFILTSSDDMLIKLWDWDKKWSCSQVFEGHTHYVMQIVINPKD 154
              HS +I  +A+     F L+SS D  ++LWD  KK S +  F  HT  V+ +  +P D
Sbjct: 153 LTGHSHFISDLALSADSRFALSSSWDATLRLWD-IKKGSTTSRFINHTRDVLTVAFSP-D 326

Query: 155 NNQFASASLDRTIKVWQ-LGSSSPNFTLEGHEKGVNCIDYYSGGDKPYLISGADDRLVKI 213
           N Q AS   D+ +K+W  +G          H   V C+ ++     P ++S ++D+ +K+
Sbjct: 327 NRQIASGGRDKNLKIWNIMGECKYTVDANAHTDWVTCVRFHQDTKNPIVVSASNDKTIKV 506

Query: 214 WDYQNKTCVQTLEGHAQNVSCASFHPELPIIITGSEDGTVRIWH 257
           WD    T   T  GH   ++          +++GS+DG    W+
Sbjct: 507 WDNHTMTLKNTFVGHKAQITALDMSTNY--LVSGSKDGIAMTWN 632

 Score = 73.6 bits (179), Expect = 3e-13,   Method: Compositional matrix adjust.
 Identities = 69/293 (23%), Positives = 126/293 (43%), Gaps = 40/293 (13%)
 Frame = +3

Query: 110 TQPFILTSSDDMLIKLWDW--------DKKWSC-SQVFEGHTHYVMQIVINPKDNNQFA- 159
           T+PF+++   D  I +WD         D+ W    +   GH+H++  + ++   +++FA 
Sbjct: 42  TKPFLISGGRDNNIIVWDL*PKKDGDEDQTWGVPRKTLTGHSHFISDLALSA--DSRFAL 215

Query: 160 SASLDRTIKVWQLGSSSPNFTLEGHEKGVNCIDYYSGGDKPYLISGADDRLVKIWDYQNK 219
           S+S D T+++W +   S       H + V  + +    D   + SG  D+ +KIW+   +
Sbjct: 216 SSSWDATLRLWDIKKGSTTSRFINHTRDVLTVAFSP--DNRQIASGGRDKNLKIWNIMGE 389

Query: 220 TCVQTLEGHAQN--VSCASFHPEL--PIIITGSEDGTVRIWHSSTYRLESTL-------- 267
            C  T++ +A    V+C  FH +   PI+++ S D T+++W + T  L++T         
Sbjct: 390 -CKYTVDANAHTDWVTCVRFHQDTKNPIVVSASNDKTIKVWDNHTMTLKNTFVGHKAQIT 566

Query: 268 ------NY-------GMERVWCVASLRGSNNVALGYDEGSIIVKLGREEPAMSM-----D 309
                 NY       G+   W VA   GS    +  D+    +K   E     +      
Sbjct: 567 ALDMSTNYLVSGSKDGIAMTWNVA--EGSFVGKIDCDDQINAIKFNIENNKKKVWLFIGT 740

Query: 310 ANGKIIWAKHSEVQQANLKAMGDTEIKDGERLPLAVKDMGSCEIYPQTIQHNP 362
            NG  IW    E +   LKA         ++ P+A   + S  + P + + +P
Sbjct: 741 QNGIQIWDYSGEKKIKELKASPIDPQNAKQKKPIACTSLASTALAPSSSEVSP 899

 Score = 37.4 bits (85), Expect = 0.025,   Method: Compositional matrix adjust.
 Identities = 32/131 (24%), Positives = 55/131 (41%), Gaps = 10/131 (7%)
 Frame = +3

Query: 196 GGDKPYLISGADDRLVKIWDY-------QNKTC---VQTLEGHAQNVSCASFHPELPIII 245
           G  KP+LISG  D  + +WD        +++T     +TL GH+  +S  +   +    +
Sbjct: 36  GATKPFLISGGRDNNIIVWDL*PKKDGDEDQTWGVPRKTLTGHSHFISDLALSADSRFAL 215

Query: 246 TGSEDGTVRIWHSSTYRLESTLNYGMERVWCVASLRGSNNVALGYDEGSIIVKLGREEPA 305
           + S D T+R+W        S        V  VA    +  +A G  + ++ +     E  
Sbjct: 216 SSSWDATLRLWDIKKGSTTSRFINHTRDVLTVAFSPDNRQIASGGRDKNLKIWNIMGECK 395

Query: 306 MSMDANGKIIW 316
            ++DAN    W
Sbjct: 396 YTVDANAHTDW 428
>27465
          Length = 658

 Score = 82.8 bits (203), Expect = 6e-16,   Method: Compositional matrix adjust.
 Identities = 51/154 (33%), Positives = 72/154 (46%), Gaps = 1/154 (0%)
 Frame = -1

Query: 104 CIAVHPTQPFILTSSDDMLIKLWDWDKKWSCSQVFEGHTHYVMQIVINPKDNNQFASASL 163
           C A   T+P      DD    L+         +V   H   +  +  N K  + F + S 
Sbjct: 433 CFACRKTRP-----KDDHHFYLF---------KVLRAHILPLTNVAFN-KSGSSFITGSY 299

Query: 164 DRTIKVWQLGSSSPNFTLEGHEKGVNCIDYYSG-GDKPYLISGADDRLVKIWDYQNKTCV 222
           DRT K+W   S+    TLEGH   V  I + +  GDK  +I+G+ D+  K+W   +  C 
Sbjct: 298 DRTCKIWDTASAEELHTLEGHRNVVYAIAFNNPFGDK--VITGSFDKTCKLWSTADGKCY 125

Query: 223 QTLEGHAQNVSCASFHPELPIIITGSEDGTVRIW 256
            TL GH   + C SF+P   +I TGS D T R+W
Sbjct: 124 HTLRGHTAEIVCVSFNPSSTLIATGSMDTTCRLW 23

 Score = 52.4 bits (124), Expect = 8e-07,   Method: Compositional matrix adjust.
 Identities = 33/127 (25%), Positives = 57/127 (44%), Gaps = 3/127 (2%)
 Frame = -1

Query: 49  LVKTFEVCDLPVRAAKFVARKNWVVTGADDMQIRVFNYNTLERVHMFEAHSDYIRCIAVH 108
           L K      LP+    F    +  +TG+ D   ++++  + E +H  E H + +  IA +
Sbjct: 385 LFKVLRAHILPLTNVAFNKSGSSFITGSYDRTCKIWDTASAEELHTLEGHRNVVYAIAFN 206

Query: 109 PTQPF---ILTSSDDMLIKLWDWDKKWSCSQVFEGHTHYVMQIVINPKDNNQFASASLDR 165
              PF   ++T S D   KLW       C     GHT  ++ +  NP  +   A+ S+D 
Sbjct: 205 --NPFGDKVITGSFDKTCKLWS-TADGKCYHTLRGHTAEIVCVSFNPS-STLIATGSMDT 38

Query: 166 TIKVWQL 172
           T ++W +
Sbjct: 37  TCRLWDV 17

 Score = 48.9 bits (115), Expect = 8e-06,   Method: Compositional matrix adjust.
 Identities = 30/89 (33%), Positives = 45/89 (50%), Gaps = 1/89 (1%)
 Frame = -1

Query: 202 LISGADDRLVKIWDYQNKTCVQTLEGHAQNVSCASFH-PELPIIITGSEDGTVRIWHSST 260
            I+G+ DR  KIWD  +   + TLEGH   V   +F+ P    +ITGS D T ++W ++ 
Sbjct: 316 FITGSYDRTCKIWDTASAEELHTLEGHRNVVYAIAFNNPFGDKVITGSFDKTCKLWSTAD 137

Query: 261 YRLESTLNYGMERVWCVASLRGSNNVALG 289
            +   TL      + CV+    S  +A G
Sbjct: 136 GKCYHTLRGHTAEIVCVSFNPSSTLIATG 50

 Score = 38.1 bits (87), Expect = 0.018,   Method: Compositional matrix adjust.
 Identities = 17/59 (28%), Positives = 31/59 (52%)
 Frame = -1

Query: 72  VVTGADDMQIRVFNYNTLERVHMFEAHSDYIRCIAVHPTQPFILTSSDDMLIKLWDWDK 130
           V+TG+ D   ++++    +  H    H+  I C++ +P+   I T S D   +LWD +K
Sbjct: 187 VITGSFDKTCKLWSTADGKCYHTLRGHTAEIVCVSFNPSSTLIATGSMDTTCRLWDVEK 11
>19949
          Length = 903

 Score = 78.6 bits (192), Expect = 1e-14,   Method: Compositional matrix adjust.
 Identities = 54/189 (28%), Positives = 93/189 (49%)
 Frame = +2

Query: 102 IRCIAVHPTQPFILTSSDDMLIKLWDWDKKWSCSQVFEGHTHYVMQIVINPKDNNQFASA 161
           ++ +  HP   +  + S D  +KLWD  +K  C   ++GHT  V  +  +P D    ASA
Sbjct: 2   VKSLDFHPYGAYTASGSMDCNVKLWDIRRK-GCIYTYKGHTGCVCCLRFSP-DGRWIASA 175

Query: 162 SLDRTIKVWQLGSSSPNFTLEGHEKGVNCIDYYSGGDKPYLISGADDRLVKIWDYQNKTC 221
           S D  +K+W L +      L+ H   VN I+++    +  L SG+ DR VK WD +    
Sbjct: 176 SEDGLVKLWDLTAGKLLTDLKLHRDAVNTIEFHP--HEFLLASGSADRTVKFWDLETFQL 349

Query: 222 VQTLEGHAQNVSCASFHPELPIIITGSEDGTVRIWHSSTYRLESTLNYGMERVWCVASLR 281
           + T E  A ++    FHP+   + +GS+D T++++H     L  T++    +V C  S+ 
Sbjct: 350 ISTTEPEANSIRSILFHPDGVCLYSGSKD-TLKVYHWEPLELYDTVSVPWGQV-CDMSIS 523

Query: 282 GSNNVALGY 290
            +  +   +
Sbjct: 524 NTQLIGASF 550

 Score = 47.0 bits (110), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 33/154 (21%), Positives = 70/154 (45%)
 Frame = +2

Query: 18  VKSVDLHPTEPWMLASLYNGSVCVWNHETQTLVKTFEVCDLPVRAAKFVARKNWVVTGAD 77
           VKS+D HP   +  +   + +V +W+   +  + T++     V   +F     W+ + ++
Sbjct: 2   VKSLDFHPYGAYTASGSMDCNVKLWDIRRKGCIYTYKGHTGCVCCLRFSPDGRWIASASE 181

Query: 78  DMQIRVFNYNTLERVHMFEAHSDYIRCIAVHPTQPFILTSSDDMLIKLWDWDKKWSCSQV 137
           D  +++++    + +   + H D +  I  HP +  + + S D  +K WD +  +     
Sbjct: 182 DGLVKLWDLTAGKLLTDLKLHRDAVNTIEFHPHEFLLASGSADRTVKFWDLE-TFQLIST 358

Query: 138 FEGHTHYVMQIVINPKDNNQFASASLDRTIKVWQ 171
            E   + +  I+ +P D     S S D T+KV+ 
Sbjct: 359 TEPEANSIRSILFHP-DGVCLYSGSKD-TLKVYH 454
>00561
          Length = 1003

 Score = 76.3 bits (186), Expect = 5e-14,   Method: Compositional matrix adjust.
 Identities = 64/233 (27%), Positives = 116/233 (49%), Gaps = 12/233 (5%)
 Frame = -3

Query: 105 IAVHPTQP-FILTSSDDMLIKLW----DWDKKWSCSQV-FEGHTHYVMQIVINPKDNNQF 158
           IA +P  P  I+++S D  + +W    D D  +   Q    GH+H++  +V++  D N  
Sbjct: 995 IATNPKDPDTIISASRDKTLIVWKLTRDEDTNYGYPQKRLYGHSHFISDVVLS-SDGNYA 819

Query: 159 ASASLDRTIKVWQLGSSSPNFTLEGHEKGVNCIDYYSGGDKPYLISGADDRLVKIWDYQN 218
            S S D+T+++W L +       EGH K V  + +    D   ++SG+ D+ +K+W+   
Sbjct: 818 LSGSWDQTLRLWDLAAGKTTRRFEGHTKDVLSVAF--SADNRQIVSGSRDKTIKLWNTLA 645

Query: 219 KTCVQTLE--GHAQNVSCASFHPEL--PIIITGSEDGTVRIWHSSTYRLESTLNYGMERV 274
           + C  T++  GH   VSC  F P    PII++   D TV++W+ +  +L++  ++G    
Sbjct: 644 E-CKFTIQEDGHTDWVSCVRFSPNHSNPIIVSCGWDRTVKVWNLANCKLKNN-HHGHN-- 477

Query: 275 WCVASLRGSNNVALGYDEGSIIVKLGREEPAMSMDAN-GKIIWA-KHSEVQQA 325
                  G  N      +GS+    G++  A+  D N GK ++  +H+++  A
Sbjct: 476 -------GYLNTVTVSPDGSLCTSGGKDSKALLWDLNDGKNLYTLEHNDIINA 339

 Score = 75.1 bits (183), Expect = 1e-13,   Method: Compositional matrix adjust.
 Identities = 54/194 (27%), Positives = 89/194 (45%), Gaps = 12/194 (6%)
 Frame = -3

Query: 97  AHSDYIRCIAVHPTQPFILTSSDDMLIKLWDWDKKWSCSQVFEGHTHYVMQIVINPKDNN 156
            HS +I  + +     + L+ S D  ++LWD       ++ FEGHT  V+ +  +  DN 
Sbjct: 872 GHSHFISDVVLSSDGNYALSGSWDQTLRLWDLAAG-KTTRRFEGHTKDVLSVAFS-ADNR 699

Query: 157 QFASASLDRTIKVWQLGSSSPNFTLE--GHEKGVNCIDYYSGGDKPYLISGADDRLVKIW 214
           Q  S S D+TIK+W   +    FT++  GH   V+C+ +      P ++S   DR VK+W
Sbjct: 698 QIVSGSRDKTIKLWNTLAEC-KFTIQEDGHTDWVSCVRFSPNHSNPIIVSCGWDRTVKVW 522

Query: 215 DYQNKTCVQTLEGHAQNVSCASFHPELPIIITGSEDGTVRIWH----SSTYRLE-----S 265
           +  N        GH   ++  +  P+  +  +G +D    +W      + Y LE     +
Sbjct: 521 NLANCKLKNNHHGHNGYLNTVTVSPDGSLCTSGGKDSKALLWDLNDGKNLYTLEHNDIIN 342

Query: 266 TLNYGMERVW-CVA 278
            L +   R W CVA
Sbjct: 341 ALCFSPNRYWLCVA 300

 Score = 64.3 bits (155), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 37/118 (31%), Positives = 63/118 (53%), Gaps = 6/118 (5%)
 Frame = -3

Query: 147 QIVINPKDNNQFASASLDRTIKVWQLGSSS------PNFTLEGHEKGVNCIDYYSGGDKP 200
           QI  NPKD +   SAS D+T+ VW+L          P   L GH   ++ +   S G+  
Sbjct: 998 QIATNPKDPDTIISASRDKTLIVWKLTRDEDTNYGYPQKRLYGHSHFISDVVLSSDGN-- 825

Query: 201 YLISGADDRLVKIWDYQNKTCVQTLEGHAQNVSCASFHPELPIIITGSEDGTVRIWHS 258
           Y +SG+ D+ +++WD       +  EGH ++V   +F  +   I++GS D T+++W++
Sbjct: 824 YALSGSWDQTLRLWDLAAGKTTRRFEGHTKDVLSVAFSADNRQIVSGSRDKTIKLWNT 651

 Score = 60.1 bits (144), Expect = 4e-09,   Method: Compositional matrix adjust.
 Identities = 44/172 (25%), Positives = 75/172 (43%), Gaps = 1/172 (0%)
 Frame = -3

Query: 70  NWVVTGADDMQIRVFNYNTLERVHMFEAHSDYIRCIAVHPTQPFILTSSDDMLIKLWDWD 129
           N+ ++G+ D  +R+++    +    FE H+  +  +A       I++ S D  IKLW+  
Sbjct: 827 NYALSGSWDQTLRLWDLAAGKTTRRFEGHTKDVLSVAFSADNRQIVSGSRDKTIKLWNTL 648

Query: 130 KKWSCSQVFEGHTHYVMQIVINPKDNNQ-FASASLDRTIKVWQLGSSSPNFTLEGHEKGV 188
            +   +   +GHT +V  +  +P  +N    S   DRT+KVW L +        GH   +
Sbjct: 647 AECKFTIQEDGHTDWVSCVRFSPNHSNPIIVSCGWDRTVKVWNLANCKLKNNHHGHNGYL 468

Query: 189 NCIDYYSGGDKPYLISGADDRLVKIWDYQNKTCVQTLEGHAQNVSCASFHPE 240
           N +     G      SG  D    +WD  +   + TLE H   ++   F P 
Sbjct: 467 NTVTVSPDGS--LCTSGGKDSKALLWDLNDGKNLYTLE-HNDIINALCFSPN 321
>12574
          Length = 521

 Score = 73.9 bits (180), Expect = 3e-13,   Method: Composition-based stats.
 Identities = 36/109 (33%), Positives = 65/109 (59%)
 Frame = +3

Query: 140 GHTHYVMQIVINPKDNNQFASASLDRTIKVWQLGSSSPNFTLEGHEKGVNCIDYYSGGDK 199
           GHT  +  +  +P + +  AS+S D+ IK+W         T+ GH+ G++ + + S  D 
Sbjct: 180 GHTKALSAVKFSP-NGDWLASSSADKLIKIWGAYDGKFEKTIAGHKLGLSDVAWSS--DS 350

Query: 200 PYLISGADDRLVKIWDYQNKTCVQTLEGHAQNVSCASFHPELPIIITGS 248
             L S +DD+ +KIW++    C++TL+GH+  V C +F+P+  +I++GS
Sbjct: 351 KLLCSASDDKTLKIWEFSTGKCMKTLKGHSNYVFCCNFNPQSNLIVSGS 497

 Score = 58.2 bits (139), Expect = 2e-08,   Method: Composition-based stats.
 Identities = 34/118 (28%), Positives = 60/118 (50%)
 Frame = +3

Query: 159 ASASLDRTIKVWQLGSSSPNFTLEGHEKGVNCIDYYSGGDKPYLISGADDRLVKIWDYQN 218
           ASA+        Q  + +  FTL GH K ++ + +   GD  +L S + D+L+KIW   +
Sbjct: 108 ASATSGTKSSATQKPTYTLKFTLAGHTKALSAVKFSPNGD--WLASSSADKLIKIWGAYD 281

Query: 219 KTCVQTLEGHAQNVSCASFHPELPIIITGSEDGTVRIWHSSTYRLESTLNYGMERVWC 276
               +T+ GH   +S  ++  +  ++ + S+D T++IW  ST +   TL      V+C
Sbjct: 282 GKFEKTIAGHKLGLSDVAWSSDSKLLCSASDDKTLKIWEFSTGKCMKTLKGHSNYVFC 455

 Score = 40.8 bits (94), Expect = 0.002,   Method: Composition-based stats.
 Identities = 25/106 (23%), Positives = 49/106 (46%)
 Frame = +3

Query: 60  VRAAKFVARKNWVVTGADDMQIRVFNYNTLERVHMFEAHSDYIRCIAVHPTQPFILTSSD 119
           + A KF    +W+ + + D  I+++     +       H   +  +A       + ++SD
Sbjct: 195 LSAVKFSPNGDWLASSSADKLIKIWGAYDGKFEKTIAGHKLGLSDVAWSSDSKLLCSASD 374

Query: 120 DMLIKLWDWDKKWSCSQVFEGHTHYVMQIVINPKDNNQFASASLDR 165
           D  +K+W++     C +  +GH++YV     NP+ +N   S SL R
Sbjct: 375 DKTLKIWEFSTG-KCMKTLKGHSNYVFCCNFNPQ-SNLIVSGSLMR 506

 Score = 38.9 bits (89), Expect = 0.008,   Method: Composition-based stats.
 Identities = 20/112 (17%), Positives = 49/112 (43%)
 Frame = +3

Query: 7   IKRKLTARSDRVKSVDLHPTEPWMLASLYNGSVCVWNHETQTLVKTFEVCDLPVRAAKFV 66
           +K  L   +  + +V   P   W+ +S  +  + +W        KT     L +    + 
Sbjct: 162 LKFTLAGHTKALSAVKFSPNGDWLASSSADKLIKIWGAYDGKFEKTIAGHKLGLSDVAWS 341

Query: 67  ARKNWVVTGADDMQIRVFNYNTLERVHMFEAHSDYIRCIAVHPTQPFILTSS 118
           +    + + +DD  ++++ ++T + +   + HS+Y+ C   +P    I++ S
Sbjct: 342 SDSKLLCSASDDKTLKIWEFSTGKCMKTLKGHSNYVFCCNFNPQSNLIVSGS 497
>02147
          Length = 1547

 Score = 67.8 bits (164), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 61/270 (22%), Positives = 113/270 (41%), Gaps = 37/270 (13%)
 Frame = +2

Query: 45  ETQTLVKTFEVCDLPVRAAKFVARKNWVVTGADDMQIRVFNYNTLERVHMFEAHSDYIRC 104
           +T   + TFE     V  A          TGA D   ++++    E +  F +H   ++ 
Sbjct: 137 DTGDWIGTFEGHKGAVWGATLNREATRAATGAADFSAKIWDAEKGEELQTF-SHKHIVKS 313

Query: 105 IAVHPTQPFILTSSDDMLIKLWDWDKKWSCSQVFEGHTHYVMQIVINPKDNNQFASASLD 164
           +        +LT S++ L+K++D     +  + F GHT  +   +    D  +  SAS D
Sbjct: 314 VDFSHDGTALLTGSNEKLLKVFDLVNTDAEPKSFAGHTSNIKGALF-LSDGKRIISASDD 490

Query: 165 RTIKVW---------QLGSSSP--NFTLEGHEKGV-----NCIDYYSG----------GD 198
           +T+++W         QL   +P  + TL   +  +       I +Y             +
Sbjct: 491 KTVRLWSLETCQEVQQLTFDTPPTSLTLSPDKNTIIVTHSQNIAFYQADTLREMKKFEAE 670

Query: 199 KP-----------YLISGADDRLVKIWDYQNKTCVQTLEGHAQNVSCASFHPELPIIITG 247
            P           + ++G +D  +  +DY+    +++ +GH   V C  F P+  +  +G
Sbjct: 671 APISSASLHQSERFFVAGGEDFKMYKFDYETGKEIESFKGHFGPVHCVRFSPDGELYASG 850

Query: 248 SEDGTVRIWHSSTYRLESTLNYGMERVWCV 277
           SEDGT+R+W ++  R      YG+ +  CV
Sbjct: 851 SEDGTLRLWQTTIGR-----TYGLWK--CV 919
>03395
          Length = 2795

 Score = 64.3 bits (155), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 49/194 (25%), Positives = 86/194 (44%), Gaps = 9/194 (4%)
 Frame = +2

Query: 72  VVTGADDMQIRVFNY--------NTLERVHMFEAHSDYIRCIAVHPTQPFILTSSDDMLI 123
           +V+G  + Q+RV++            + V   + H   +  I +H      +++S D   
Sbjct: 41  LVSGGGEGQVRVWDIVKDMLTGKTRGDLVANMKEHKGKVTAIQIHTNDRCCVSASTDGST 220

Query: 124 KLWDWDKKWSCSQVFEGHTHYVMQIVINPKDNNQFASASLDRTIKVWQLGSSSPNFTLEG 183
            +WD     + SQ+   +T +   +    KD +   S + D  I  W++G       LEG
Sbjct: 221 IIWDLITN-TRSQIVLANTLFKC-VCFGGKDLHILTSGT-DHKIGYWEVGDGGLLRELEG 391

Query: 184 HEKG-VNCIDYYSGGDKPYLISGADDRLVKIWDYQNKTCVQTLEGHAQNVSCASFHPELP 242
            + G +N ID     D   +++G +D L+K+W Y       T  GH+  ++ A   P   
Sbjct: 392 SQTGAINTIDIDR--DGQTILTGGEDSLLKLWRYNEGEVTHTGIGHSNQITKARICPNRH 565

Query: 243 IIITGSEDGTVRIW 256
            I++G EDG + IW
Sbjct: 566 YIVSGGEDGALHIW 607

 Score = 35.8 bits (81), Expect = 0.086,   Method: Compositional matrix adjust.
 Identities = 34/170 (20%), Positives = 65/170 (38%)
 Frame = +2

Query: 60  VRAAKFVARKNWVVTGADDMQIRVFNYNTLERVHMFEAHSDYIRCIAVHPTQPFILTSSD 119
           V A +        V+ + D    +++  T  R  +  A++ + +C+        ILTS  
Sbjct: 155 VTAIQIHTNDRCCVSASTDGSTIIWDLITNTRSQIVLANTLF-KCVCFGGKDLHILTSGT 331

Query: 120 DMLIKLWDWDKKWSCSQVFEGHTHYVMQIVINPKDNNQFASASLDRTIKVWQLGSSSPNF 179
           D  I  W+        ++    T  +  I I+ +D     +   D  +K+W+        
Sbjct: 332 DHKIGYWEVGDGGLLRELEGSQTGAINTIDID-RDGQTILTGGEDSLLKLWRYNEGEVTH 508

Query: 180 TLEGHEKGVNCIDYYSGGDKPYLISGADDRLVKIWDYQNKTCVQTLEGHA 229
           T  GH   +         ++ Y++SG +D  + IW + +   V  L  H 
Sbjct: 509 TGIGHSNQITKARICP--NRHYIVSGGEDGALHIWKFPDGC*VDCLPRHG 652
>18981
          Length = 407

 Score = 63.9 bits (154), Expect = 3e-10,   Method: Composition-based stats.
 Identities = 41/137 (29%), Positives = 67/137 (48%), Gaps = 1/137 (0%)
 Frame = -2

Query: 155 NNQFASASLDRTIKVWQLGSSSPNFTLEGHEKGVNCIDYYSGGDKPYLISGADDRLVKIW 214
           +N   SA+ DRT++VW L ++    TL GH   V C+  Y       ++SG+ D+ + +W
Sbjct: 388 DNMIISAATDRTLRVWCLKNTCLLHTLRGHNDDVECVCIYG----RRVVSGSWDKTLIVW 221

Query: 215 DYQNKTCVQTLEGHAQNVSCASFHPELPIIITGSEDGTVRIWHSSTYRLESTLNYGME-R 273
           +      V  L GH + ++   F  +    ++GS DG VR W   T +   T+  G +  
Sbjct: 220 EVDTGRPVHQLHGHTEAITAVQF--DEGKAVSGSADGDVRTWALDTGQCLLTMTTGQDIE 47

Query: 274 VWCVASLRGSNNVALGY 290
           V+CV  +     +A GY
Sbjct: 46  VYCV--VYNQEVIAAGY 2
>01768
          Length = 1424

 Score = 63.2 bits (152), Expect = 4e-10,   Method: Compositional matrix adjust.
 Identities = 43/135 (31%), Positives = 74/135 (54%), Gaps = 10/135 (7%)
 Frame = +3

Query: 138 FEGHTHYVMQIVINPKDNNQFASASLDRTIKVW---QLGSSSPNFTL-EGHEKGVNCIDY 193
           +  HT  V  +  +P + N FAS S+DRT+++W   Q  S +   T+ E H + +N I+ 
Sbjct: 825 YAAHTDSVEDVQWSPNEGNVFASCSVDRTLRIWNTQQKPSKANVLTVPEAHSRDINVIN- 1001

Query: 194 YSGGDKPYLISGADDRLVKIWD---YQNK--TCVQTLEGHAQNVSCASFHPELPIIITGS 248
           ++  +K  L SG DD ++KIWD   ++NK  +   + + H+Q V+   ++P+   ++  S
Sbjct: 1002WNPIEKHLLASGGDDGIIKIWDLRMFRNKPVSAQASFKLHSQPVTSLEWNPQDSSVLAAS 1181

Query: 249 -EDGTVRIWHSSTYR 262
            ED  + IW  S  R
Sbjct: 1182GEDDQITIWDFSVER 1226

 Score = 42.4 bits (98), Expect = 9e-04,   Method: Compositional matrix adjust.
 Identities = 27/82 (32%), Positives = 42/82 (51%), Gaps = 5/82 (6%)
 Frame = +3

Query: 96   EAHSDYIRCIAVHPTQPFILTSS-DDMLIKLWDW----DKKWSCSQVFEGHTHYVMQIVI 150
            EAHS  I  I  +P +  +L S  DD +IK+WD     +K  S    F+ H+  V  +  
Sbjct: 969  EAHSRDINVINWNPIEKHLLASGGDDGIIKIWDLRMFRNKPVSAQASFKLHSQPVTSLEW 1148

Query: 151  NPKDNNQFASASLDRTIKVWQL 172
            NP+D++  A++  D  I +W  
Sbjct: 1149 NPQDSSVLAASGEDDQITIWDF 1214
>26939
          Length = 388

 Score = 62.0 bits (149), Expect = 9e-10,   Method: Composition-based stats.
 Identities = 23/56 (41%), Positives = 37/56 (66%)
 Frame = +2

Query: 201 YLISGADDRLVKIWDYQNKTCVQTLEGHAQNVSCASFHPELPIIITGSEDGTVRIW 256
           YL+S +DD+ +++WD +NK C++TL  H    +   FH   P +I+GS D TV++W
Sbjct: 8   YLVSASDDKTIRVWDLRNKRCMKTLYAHQHFCTSIDFHKAHPYVISGSVDQTVKVW 175

 Score = 45.8 bits (107), Expect = 8e-05,   Method: Composition-based stats.
 Identities = 23/58 (39%), Positives = 34/58 (58%)
 Frame = +2

Query: 158 FASASLDRTIKVWQLGSSSPNFTLEGHEKGVNCIDYYSGGDKPYLISGADDRLVKIWD 215
             SAS D+TI+VW L +     TL  H+     ID++     PY+ISG+ D+ VK+W+
Sbjct: 11  LVSASDDKTIRVWDLRNKRCMKTLYAHQHFCTSIDFHKA--HPYVISGSVDQTVKVWE 178

 Score = 40.0 bits (92), Expect = 0.004,   Method: Composition-based stats.
 Identities = 19/59 (32%), Positives = 34/59 (57%)
 Frame = +2

Query: 113 FILTSSDDMLIKLWDWDKKWSCSQVFEGHTHYVMQIVINPKDNNQFASASLDRTIKVWQ 171
           +++++SDD  I++WD   K  C +    H H+   I  + K +    S S+D+T+KVW+
Sbjct: 8   YLVSASDDKTIRVWDLRNK-RCMKTLYAHQHFCTSIDFH-KAHPYVISGSVDQTVKVWE 178

 Score = 38.5 bits (88), Expect = 0.012,   Method: Composition-based stats.
 Identities = 15/57 (26%), Positives = 30/57 (52%)
 Frame = +2

Query: 71  WVVTGADDMQIRVFNYNTLERVHMFEAHSDYIRCIAVHPTQPFILTSSDDMLIKLWD 127
           ++V+ +DD  IRV++      +    AH  +   I  H   P++++ S D  +K+W+
Sbjct: 8   YLVSASDDKTIRVWDLRNKRCMKTLYAHQHFCTSIDFHKAHPYVISGSVDQTVKVWE 178
>01327
          Length = 2215

 Score = 62.0 bits (149), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 48/156 (30%), Positives = 72/156 (46%), Gaps = 6/156 (3%)
 Frame = +3

Query: 111 QP-FILTSSDDMLIKLWDW-----DKKWSCSQVFEGHTHYVMQIVINPKDNNQFASASLD 164
           QP   L+ S D  + L+D+     + +W+      GH   + ++      N  F SAS D
Sbjct: 72  QPGLCLSGSKDKSVVLYDYQNGRLEDRWT------GHDREITKVCYGASCNGMF-SASRD 230

Query: 165 RTIKVWQLGSSSPNFTLEGHEKGVNCIDYYSGGDKPYLISGADDRLVKIWDYQNKTCVQT 224
           +TIK+WQ G+S       GH+  V  I   +  D   L SG+ D  V+IWD +   C++ 
Sbjct: 231 KTIKMWQRGNSHSIRDFIGHDMVVTAIHLNT--DNTLLCSGSRDNTVRIWDVETGACLRQ 404

Query: 225 LEGHAQNVSCASFHPELPIIITGSEDGTVRIWHSST 260
                  V+   + P   +II   ED  VRI+ S T
Sbjct: 405 NNIPQNLVTDVKWLPGSHLIIQAGEDKEVRIYDSRT 512

 Score = 37.7 bits (86), Expect = 0.023,   Method: Compositional matrix adjust.
 Identities = 51/268 (19%), Positives = 103/268 (38%), Gaps = 9/268 (3%)
 Frame = +3

Query: 30  MLASLYNGSVCVWNHETQTLVKTFEVCDLPVRAAKFVARKNWVVTGADDMQIRVFNYNTL 89
           M ++  + ++ +W       ++ F   D+ V A         + +G+ D  +R+++  T 
Sbjct: 210 MFSASRDKTIKMWQRGNSHSIRDFIGHDMVVTAIHLNTDNTLLCSGSRDNTVRIWDVETG 389

Query: 90  ERVHMFEAHSDYIRCIAVHPTQPFILTSSDDMLIKLWDWDKKWSCSQVFEGHTHYVMQIV 149
             +       + +  +   P    I+ + +D  ++++D  +     + F    +  M   
Sbjct: 390 ACLRQNNIPQNLVTDVKWLPGSHLIIQAGEDKEVRIYD-SRTLGIVRSFTKKQYIQMSCD 566

Query: 150 INPKD------NNQFASASLDRTIKVWQLGSSSPNFTLEGHEKGVN-CIDYYSGGDKPYL 202
           +          +N F     + T+  WQL   S     +GH + +  C+   S  D   +
Sbjct: 567 VTADGQFCLTCSNGFGGNGCEATL--WQLSDGSIQNEFKGHREAIEACLFLPSNQDMTLI 740

Query: 203 ISGADDRLVKIWDYQNKTCV--QTLEGHAQNVSCASFHPELPIIITGSEDGTVRIWHSST 260
            + + D  V++W+   K CV  Q  EG           P   +I  G  DG+V       
Sbjct: 741 ATASRDCSVRVWNMFTKECVCEQNFEGTG---------PLTSMIAYG--DGSV------- 866

Query: 261 YRLESTLNYGMERVWCVASLRGSNNVAL 288
             L  T N G++    V SL G +++ +
Sbjct: 867 --LVGTFNLGVQ----VMSLNGQSSLDI 932
>13335
          Length = 863

 Score = 61.2 bits (147), Expect = 2e-09,   Method: Composition-based stats.
 Identities = 56/243 (23%), Positives = 107/243 (44%), Gaps = 25/243 (10%)
 Frame = +1

Query: 39  VCVWNHETQTLVKTFE-VCDLPVRAAKFVARKNWVVTGADDMQIRVFNYNTLERVHMFEA 97
           V VW+ +T ++   ++      +R  KF    + +V+G+DD  I ++   T + V  +  
Sbjct: 4   VIVWDVKTGSIKGEYQHASKSSIRVCKFSPSSSHLVSGSDDDTICMWEVATQKLVRSYVG 183

Query: 98  HSDYIRCIAVHPTQPFILTSSDDMLIKLWDWDKKWS-CSQV---FEGHTHYVMQIVINPK 153
           H D +  +A  P   ++++ S +    L+ WD  +  C  +    + H   V     +P 
Sbjct: 184 HEDSVMALAYSPNGHYLVSGSPNG--DLYVWDASFGHCRHLTLRVDAHDLGVTCCEFSPT 357

Query: 154 ------DNNQ-----FASASLDRTIKVWQLGSS--SPNFTLE------GHEKGVNCIDYY 194
                 +N+       A+   D  IK+W   +   SP  TL+      GH   V    + 
Sbjct: 358 FGTACAENSSTCNLLLATGGKDNLIKLWTFSAQVGSPEVTLQCRDILSGHSDLVMACAF- 534

Query: 195 SGGDKPYLISGADDRLVKIWDYQNKTCVQTLEG-HAQNVSCASFHPELPIIITGSEDGTV 253
                  L SG+ D+ V++WD      + ++E  H++ V+C +F  +  ++ +GS D  +
Sbjct: 535 -SPSSALLASGSFDKSVRLWDSVKGVALFSIEACHSRFVTCCAFSIDGTLLASGSMDRII 711

Query: 254 RIW 256
           +IW
Sbjct: 712 KIW 720

 Score = 58.9 bits (141), Expect = 8e-09,   Method: Composition-based stats.
 Identities = 45/183 (24%), Positives = 77/183 (42%), Gaps = 21/183 (11%)
 Frame = +1

Query: 97  AHSDYIRCIAVHPTQPFILTSSDDMLIKLWDWDKKWSCSQVFEGHTHYVMQIVINPKDNN 156
           A    IR     P+   +++ SDD  I +W+   +    + + GH   VM +  +P + +
Sbjct: 55  ASKSSIRVCKFSPSSSHLVSGSDDDTICMWEVATQ-KLVRSYVGHEDSVMALAYSP-NGH 228

Query: 157 QFASASLDRTIKVWQLG-SSSPNFTL--EGHEKGVNCIDYY----------SGGDKPYLI 203
              S S +  + VW        + TL  + H+ GV C ++           S      L 
Sbjct: 229 YLVSGSPNGDLYVWDASFGHCRHLTLRVDAHDLGVTCCEFSPTFGTACAENSSTCNLLLA 408

Query: 204 SGADDRLVKIWDYQNKT--------CVQTLEGHAQNVSCASFHPELPIIITGSEDGTVRI 255
           +G  D L+K+W +  +         C   L GH+  V   +F P   ++ +GS D +VR+
Sbjct: 409 TGGKDNLIKLWTFSAQVGSPEVTLQCRDILSGHSDLVMACAFSPSSALLASGSFDKSVRL 588

Query: 256 WHS 258
           W S
Sbjct: 589 WDS 597

 Score = 52.4 bits (124), Expect = 7e-07,   Method: Composition-based stats.
 Identities = 44/191 (23%), Positives = 79/191 (41%), Gaps = 23/191 (12%)
 Frame = +1

Query: 9   RKLTARSDRVKSVDLHPTEPWMLASLYNGSVCVWNH---ETQTLVKTFEVCDLPVRAAKF 65
           R      D V ++   P   ++++   NG + VW+      + L    +  DL V   +F
Sbjct: 169 RSYVGHEDSVMALAYSPNGHYLVSGSPNGDLYVWDASFGHCRHLTLRVDAHDLGVTCCEF 348

Query: 66  ------VARKN------WVVTGADDMQIRVFNYN--------TLERVHMFEAHSDYIRCI 105
                    +N       + TG  D  I+++ ++        TL+   +   HSD +   
Sbjct: 349 SPTFGTACAENSSTCNLLLATGGKDNLIKLWTFSAQVGSPEVTLQCRDILSGHSDLVMAC 528

Query: 106 AVHPTQPFILTSSDDMLIKLWDWDKKWSCSQVFEGHTHYVMQIVINPKDNNQFASASLDR 165
           A  P+   + + S D  ++LWD  K  +   +   H+ +V     +  D    AS S+DR
Sbjct: 529 AFSPSSALLASGSFDKSVRLWDSVKGVALFSIEACHSRFVTCCAFS-IDGTLLASGSMDR 705

Query: 166 TIKVWQLGSSS 176
            IK+W+L  +S
Sbjct: 706 IIKIWKLTDTS 738

 Score = 43.1 bits (100), Expect = 5e-04,   Method: Composition-based stats.
 Identities = 16/59 (27%), Positives = 35/59 (59%)
 Frame = +1

Query: 201 YLISGADDRLVKIWDYQNKTCVQTLEGHAQNVSCASFHPELPIIITGSEDGTVRIWHSS 259
           +L+SG+DD  + +W+   +  V++  GH  +V   ++ P    +++GS +G + +W +S
Sbjct: 103 HLVSGSDDDTICMWEVATQKLVRSYVGHEDSVMALAYSPNGHYLVSGSPNGDLYVWDAS 279
>03156
          Length = 1014

 Score = 59.3 bits (142), Expect = 7e-09,   Method: Compositional matrix adjust.
 Identities = 40/123 (32%), Positives = 58/123 (47%)
 Frame = +1

Query: 138 FEGHTHYVMQIVINPKDNNQFASASLDRTIKVWQLGSSSPNFTLEGHEKGVNCIDYYSGG 197
           + GH   + ++      N  F SAS D+TIK+WQ G+S       GH+  V  I   +  
Sbjct: 43  WTGHDREITKVCYGASCNGMF-SASRDKTIKMWQRGNSHSIRDFIGHDMVVTAIHLNT-- 213

Query: 198 DKPYLISGADDRLVKIWDYQNKTCVQTLEGHAQNVSCASFHPELPIIITGSEDGTVRIWH 257
           D   L SG+ D  V+IWD +   C++        V+   + P   +II   ED  VRI+ 
Sbjct: 214 DNTLLCSGSRDNTVRIWDVETGACLRQNNIPQNLVTDVKWLPGSHLIIQAGEDKEVRIYD 393

Query: 258 SST 260
           S T
Sbjct: 394 SRT 402

 Score = 38.1 bits (87), Expect = 0.017,   Method: Compositional matrix adjust.
 Identities = 51/268 (19%), Positives = 103/268 (38%), Gaps = 9/268 (3%)
 Frame = +1

Query: 30  MLASLYNGSVCVWNHETQTLVKTFEVCDLPVRAAKFVARKNWVVTGADDMQIRVFNYNTL 89
           M ++  + ++ +W       ++ F   D+ V A         + +G+ D  +R+++  T 
Sbjct: 100 MFSASRDKTIKMWQRGNSHSIRDFIGHDMVVTAIHLNTDNTLLCSGSRDNTVRIWDVETG 279

Query: 90  ERVHMFEAHSDYIRCIAVHPTQPFILTSSDDMLIKLWDWDKKWSCSQVFEGHTHYVMQIV 149
             +       + +  +   P    I+ + +D  ++++D  +     + F    +  M   
Sbjct: 280 ACLRQNNIPQNLVTDVKWLPGSHLIIQAGEDKEVRIYD-SRTLGIVRSFTKKQYIQMSCD 456

Query: 150 INPKD------NNQFASASLDRTIKVWQLGSSSPNFTLEGHEKGVN-CIDYYSGGDKPYL 202
           +          +N F     + T+  WQL   S     +GH + +  C+   S  D   +
Sbjct: 457 VTADGQFCLTCSNGFGGNGCEATL--WQLSDGSIQNEFKGHREAIEACLFLPSNQDMTLI 630

Query: 203 ISGADDRLVKIWDYQNKTCV--QTLEGHAQNVSCASFHPELPIIITGSEDGTVRIWHSST 260
            + + D  V++W+   K CV  Q  EG           P   +I  G  DG+V       
Sbjct: 631 ATASRDCSVRVWNMFTKECVCEQNFEGTG---------PLTSMIAYG--DGSV------- 756

Query: 261 YRLESTLNYGMERVWCVASLRGSNNVAL 288
             L  T N G++    V SL G +++ +
Sbjct: 757 --LVGTFNLGVQ----VMSLNGQSSLDI 822
>37180
          Length = 681

 Score = 57.0 bits (136), Expect = 3e-08,   Method: Composition-based stats.
 Identities = 28/80 (35%), Positives = 41/80 (51%)
 Frame = +1

Query: 93  HMFEAHSDYIRCIAVHPTQPFILTSSDDMLIKLWDWDKKWSCSQVFEGHTHYVMQIVINP 152
           ++   H   +  +  HPTQ  ++TSS DM  +LWD+        VF+GHT  V   V   
Sbjct: 1   NVLNGHDQELSDVHAHPTQRLVVTSSKDMTFRLWDFRDSALLVNVFQGHTQPVTSAVFAS 180

Query: 153 KDNNQFASASLDRTIKVWQL 172
            D  +  S S DRT++VW +
Sbjct: 181 GD--KVVSGSDDRTVRVWDM 234

 Score = 42.0 bits (97), Expect = 0.001,   Method: Composition-based stats.
 Identities = 22/83 (26%), Positives = 45/83 (54%), Gaps = 1/83 (1%)
 Frame = +1

Query: 181 LEGHEKGVNCIDYYSGGDKPYLISGADDRLVKIWDYQNKTC-VQTLEGHAQNVSCASFHP 239
           L GH++ ++  D ++   +  +++ + D   ++WD+++    V   +GH Q V+ A F  
Sbjct: 7   LNGHDQELS--DVHAHPTQRLVVTSSKDMTFRLWDFRDSALLVNVFQGHTQPVTSAVFAS 180

Query: 240 ELPIIITGSEDGTVRIWHSSTYR 262
               +++GS+D TVR+W     R
Sbjct: 181 G-DKVVSGSDDRTVRVWDMRNMR 246

 Score = 39.3 bits (90), Expect = 0.006,   Method: Composition-based stats.
 Identities = 24/83 (28%), Positives = 43/83 (51%), Gaps = 1/83 (1%)
 Frame = +1

Query: 137 VFEGHTHYVMQIVINPKDNNQFASASLDRTIKVWQLGSSSPNFTL-EGHEKGVNCIDYYS 195
           V  GH   +  +  +P       ++S D T ++W    S+    + +GH + V     ++
Sbjct: 4   VLNGHDQELSDVHAHPT-QRLVVTSSKDMTFRLWDFRDSALLVNVFQGHTQPVTSA-VFA 177

Query: 196 GGDKPYLISGADDRLVKIWDYQN 218
            GDK  ++SG+DDR V++WD +N
Sbjct: 178 SGDK--VVSGSDDRTVRVWDMRN 240

 Score = 32.3 bits (72), Expect = 0.82,   Method: Composition-based stats.
 Identities = 20/73 (27%), Positives = 32/73 (43%)
 Frame = +1

Query: 225 LEGHAQNVSCASFHPELPIIITGSEDGTVRIWHSSTYRLESTLNYGMERVWCVASLRGSN 284
           L GH Q +S    HP   +++T S+D T R+W      L   +  G  +    A     +
Sbjct: 7   LNGHDQELSDVHAHPTQRLVVTSSKDMTFRLWDFRDSALLVNVFQGHTQPVTSAVFASGD 186

Query: 285 NVALGYDEGSIIV 297
            V  G D+ ++ V
Sbjct: 187 KVVSGSDDRTVRV 225
>03387
          Length = 1891

 Score = 56.6 bits (135), Expect = 5e-08,   Method: Compositional matrix adjust.
 Identities = 43/158 (27%), Positives = 72/158 (45%), Gaps = 15/158 (9%)
 Frame = +1

Query: 114 ILTSSDDMLIKLWDWDKKWSCSQV------FEGHTHYVMQIVINPKDNNQFASASLDRTI 167
           +L++SDD  I LWD +     S+V      F GHT  V  +  +    + F S + D+ +
Sbjct: 409 LLSASDDHTICLWDINSTQRESRVVDAHTIFTGHTSVVEDVAWHLLHESLFGSVADDQKL 588

Query: 168 KVWQLGS---SSPNFTLEGHEKGVNCIDYYSGGDKPY----LISGADDRLVKIWDYQN-K 219
            +W   S   S P+  ++ H   VNC+ +      PY    L +G+ D+ V +WD +N K
Sbjct: 589 MIWDTRSNTTSKPSHVVDAHTAEVNCLSF-----NPYSEFILATGSADKTVALWDLRNLK 753

Query: 220 TCVQTLEGHAQNVSCASFHPELPIIITGS-EDGTVRIW 256
             + + E H   +    + P    I+  S  D  + +W
Sbjct: 754 LKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLHVW 867

 Score = 55.8 bits (133), Expect = 8e-08,   Method: Compositional matrix adjust.
 Identities = 46/210 (21%), Positives = 93/210 (44%), Gaps = 25/210 (11%)
 Frame = +1

Query: 30  MLASLYNGSVCVWN-HETQTLVKTFEVCDLPVRAAKFVARKNWVV-------TGADDMQI 81
           +L++  + ++C+W+ + TQ   +  +   +       V    W +       + ADD ++
Sbjct: 409 LLSASDDHTICLWDINSTQRESRVVDAHTIFTGHTSVVEDVAWHLLHESLFGSVADDQKL 588

Query: 82  RVFNY---NTLERVHMFEAHSDYIRCIAVHPTQPFIL-TSSDDMLIKLWDWDKKWSCSQV 137
            +++     T +  H+ +AH+  + C++ +P   FIL T S D  + LWD          
Sbjct: 589 MIWDTRSNTTSKPSHVVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHS 768

Query: 138 FEGHTHYVMQIVINPKDNNQFASASLDRTIKVWQLGSSSPNFTLEGHEKGVNCIDYYSGG 197
           FE H   + Q+  +P +    AS+  DR + VW L         E  E G   + +  GG
Sbjct: 769 FESHKDEIFQVQWSPHNETILASSGTDRRLHVWDLSKIGEEQLPEDAEDGPPELLFIHGG 948

Query: 198 ------------DKPYLI-SGADDRLVKIW 214
                       ++P+++ S ++D ++++W
Sbjct: 949 HTAKISDFSWNPNEPWIVCSVSEDNIMQVW 1038

 Score = 49.3 bits (116), Expect = 8e-06,   Method: Compositional matrix adjust.
 Identities = 39/138 (28%), Positives = 63/138 (45%), Gaps = 11/138 (7%)
 Frame = +1

Query: 138 FEGHTHYVMQIVINPKDNNQFASASLDRTIKVWQLGSS-------SPNFTLEGHEKGVNC 190
            +GH      +  NP  N    SAS D TI +W + S+         +    GH   V  
Sbjct: 349 LKGHQKEGYGLSWNPNLNGHLLSASDDHTICLWDINSTQRESRVVDAHTIFTGHTSVVED 528

Query: 191 IDYYSGGDKPYLISGADDRLVKIWDYQNKTCVQ---TLEGHAQNVSCASFHPELPIII-T 246
           + ++   +  +  S ADD+ + IWD ++ T  +    ++ H   V+C SF+P    I+ T
Sbjct: 529 VAWHLLHESLFG-SVADDQKLMIWDTRSNTTSKPSHVVDAHTAEVNCLSFNPYSEFILAT 705

Query: 247 GSEDGTVRIWHSSTYRLE 264
           GS D TV +W     +L+
Sbjct: 706 GSADKTVALWDLRNLKLK 759

 Score = 38.9 bits (89), Expect = 0.009,   Method: Compositional matrix adjust.
 Identities = 45/190 (23%), Positives = 76/190 (40%), Gaps = 21/190 (11%)
 Frame = +1

Query: 5   LDIKRKLTARSDRVKSVDLHPTEPWMLASLYNGS-VCVWNHETQTLVKTFEVCDL---PV 60
           +D     T  +  V+ V  H     +  S+ +   + +W+  + T  K   V D     V
Sbjct: 481 VDAHTIFTGHTSVVEDVAWHLLHESLFGSVADDQKLMIWDTRSNTTSKPSHVVDAHTAEV 660

Query: 61  RAAKFVARKNWVV-TGADDMQIRVFNYNTLE-RVHMFEAHSDYIRCIAVHPTQPFILTSS 118
               F     +++ TG+ D  + +++   L+ ++H FE+H D I  +   P    IL SS
Sbjct: 661 NCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASS 840

Query: 119 D-DMLIKLWDWDKKWSCSQVFE--------------GHTHYVMQIVINPKDNNQFASASL 163
             D  + +WD  K     Q+ E              GHT  +     NP +     S S 
Sbjct: 841 GTDRRLHVWDLSKI-GEEQLPEDAEDGPPELLFIHGGHTAKISDFSWNPNEPWIVCSVSE 1017

Query: 164 DRTIKVWQLG 173
           D  ++VWQ+ 
Sbjct: 1018DNIMQVWQMA 1047
>31474
          Length = 403

 Score = 54.7 bits (130), Expect = 2e-07,   Method: Composition-based stats.
 Identities = 37/110 (33%), Positives = 53/110 (48%), Gaps = 4/110 (3%)
 Frame = -3

Query: 88  TLERVHMFEAHSDYIRCIAVHPTQPFILTSSDDMLIKLWDWD-KKWSC-SQVFEGHTHYV 145
           TLE V    AH ++  C+A +PT   + +   D +IK+W  +   W C S + + HT  V
Sbjct: 338 TLEEVCCLSAHDEHAWCVAWNPTGTLLASCGSDKIIKIWGKEGDNWVCKSTLTDAHTRTV 159

Query: 146 MQIVINPKDNNQFASASLDRTIKVWQL--GSSSPNFTLEGHEKGVNCIDY 193
             +  +P   N  +SAS D T  VW    G      TLEGHE  V  + +
Sbjct: 158 RSLGWSPC-GNYLSSASFDATTAVWSRKGGEFECIATLEGHENEVKAVAW 12

 Score = 33.1 bits (74), Expect = 0.48,   Method: Composition-based stats.
 Identities = 26/107 (24%), Positives = 42/107 (39%), Gaps = 7/107 (6%)
 Frame = -3

Query: 138 FEGHTHYVMQIVINPKDNNQFASASLDRTIKVWQLGSSSPNFT-----LEGHEKGVNCID 192
              H  +   +  NP      AS   D+ IK+W  G    N+       + H + V  + 
Sbjct: 317 LSAHDEHAWCVAWNPT-GTLLASCGSDKIIKIW--GKEGDNWVCKSTLTDAHTRTVRSLG 147

Query: 193 YYSGGDKPYLISGADDRLVKIWDYQNKT--CVQTLEGHAQNVSCASF 237
           +   G+  YL S + D    +W  +     C+ TLEGH   V   ++
Sbjct: 146 WSPCGN--YLSSASFDATTAVWSRKGGEFECIATLEGHENEVKAVAW 12
>17602
          Length = 481

 Score = 48.5 bits (114), Expect(2) = 2e-07,   Method: Compositional matrix adjust.
 Identities = 34/136 (25%), Positives = 64/136 (47%), Gaps = 2/136 (1%)
 Frame = +3

Query: 82  RVFNYNTLERVHMFEAHSDYIRCIAVHPTQPFILTSSDDMLIKLWDWDKKWSCSQVFEGH 141
           R+++  T + +    AHSD +  +  +     I++SS D L ++WD         + +  
Sbjct: 3   RIWDVKTGKCLKTLPAHSDPVTAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLXTLIDDD 182

Query: 142 THYVMQIVINPKDNNQFASASLDRTIKVWQLGSSSPNFTLEGHEKGVNCI--DYYSGGDK 199
              V  +  +P +     +A+LD T+K+W         T  GH     CI  ++   G K
Sbjct: 183 NPPVSFVKFSP-NGKYILAATLDNTLKLWDYSKGKCLKTYVGHRNEKYCIFANFSVTGGK 359

Query: 200 PYLISGADDRLVKIWD 215
            +++SG++D +V IW+
Sbjct: 360 -WIVSGSEDNMVYIWN 404

 Score = 25.4 bits (54), Expect(2) = 2e-07,   Method: Composition-based stats.
 Identities = 10/21 (47%), Positives = 12/21 (57%)
 Frame = +1

Query: 219 KTCVQTLEGHAQNVSCASFHP 239
           K  VQ L+GH   V C + HP
Sbjct: 415 KEIVQKLQGHTDVVLCCACHP 477

 Score = 49.7 bits (117), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 38/138 (27%), Positives = 63/138 (45%), Gaps = 4/138 (2%)
 Frame = +3

Query: 124 KLWDWDKKWSCSQVFEGHTHYVMQIVINPKDNNQFASASLDRTIKVWQLGSSSPNFTL-E 182
           ++WD  K   C +    H+  V  +  N +D +   S+S D   ++W   S     TL +
Sbjct: 3   RIWD-VKTGKCLKTLPAHSDPVTAVHFN-RDGSLIVSSSYDGLCRIWDTASGQCLXTLID 176

Query: 183 GHEKGVNCIDYYSGGDKPYLISGADDRLVKIWDYQNKTCVQTLEGHAQNVSC--ASFH-P 239
                V+ + +   G   Y+++   D  +K+WDY    C++T  GH     C  A+F   
Sbjct: 177 DDNPPVSFVKFSPNG--KYILAATLDNTLKLWDYSKGKCLKTYVGHRNEKYCIFANFSVT 350

Query: 240 ELPIIITGSEDGTVRIWH 257
               I++GSED  V IW+
Sbjct: 351 GGKWIVSGSEDNMVYIWN 404

 Score = 38.1 bits (87), Expect = 0.016,   Method: Compositional matrix adjust.
 Identities = 24/93 (25%), Positives = 42/93 (45%), Gaps = 1/93 (1%)
 Frame = +3

Query: 168 KVWQLGSSSPNFTLEGHEKGVNCIDYYSGGDKPYLISGADDRLVKIWDYQNKTCVQTL-E 226
           ++W + +     TL  H   V  + +    D   ++S + D L +IWD  +  C+ TL +
Sbjct: 3   RIWDVKTGKCLKTLPAHSDPVTAVHFNR--DGSLIVSSSYDGLCRIWDTASGQCLXTLID 176

Query: 227 GHAQNVSCASFHPELPIIITGSEDGTVRIWHSS 259
                VS   F P    I+  + D T+++W  S
Sbjct: 177 DDNPPVSFVKFSPNGKYILAATLDNTLKLWDYS 275

 Score = 38.1 bits (87), Expect = 0.017,   Method: Compositional matrix adjust.
 Identities = 25/123 (20%), Positives = 60/123 (48%), Gaps = 4/123 (3%)
 Frame = +3

Query: 9   RKLTARSDRVKSVDLHPTEPWMLASLYNGSVCVWNHET-QTLVKTFEVCDLPVRAAKFVA 67
           + L A SD V +V  +     +++S Y+G   +W+  + Q L    +  + PV   KF  
Sbjct: 36  KTLPAHSDPVTAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLXTLIDDDNPPVSFVKFSP 215

Query: 68  RKNWVVTGADDMQIRVFNYNTLERVHMFEAHSDYIRCIAVHPT---QPFILTSSDDMLIK 124
              +++    D  +++++Y+  + +  +  H +   CI  + +     +I++ S+D ++ 
Sbjct: 216 NGKYILAATLDNTLKLWDYSKGKCLKTYVGHRNEKYCIFANFSVTGGKWIVSGSEDNMVY 395

Query: 125 LWD 127
           +W+
Sbjct: 396 IWN 404
>14555
          Length = 627

 Score = 38.5 bits (88), Expect(2) = 3e-07,   Method: Composition-based stats.
 Identities = 19/50 (38%), Positives = 24/50 (48%)
 Frame = -3

Query: 207 DDRLVKIWDYQNKTCVQTLEGHAQNVSCASFHPELPIIITGSEDGTVRIW 256
           +D  V +WD         L GH   VSC    P+   + TGS D T+RIW
Sbjct: 406 NDYTVNVWDALKGMRSTILYGHDNRVSCLRISPDGTSLCTGSWDYTLRIW 257

 Score = 34.7 bits (78), Expect(2) = 3e-07,   Method: Composition-based stats.
 Identities = 13/35 (37%), Positives = 21/35 (60%)
 Frame = -2

Query: 181 LEGHEKGVNCIDYYSGGDKPYLISGADDRLVKIWD 215
            EGHE  +NC+ +Y  GD     +G+DD   +++D
Sbjct: 611 FEGHEADINCVRFYPSGDA--FATGSDDATCRLFD 513

 Score = 34.7 bits (78), Expect(2) = 3e-04,   Method: Composition-based stats.
 Identities = 17/47 (36%), Positives = 25/47 (53%), Gaps = 2/47 (4%)
 Frame = -2

Query: 90  ERVHMFEAHSDYIRCIAVHPTQPFILTSSDDMLIKLWDW--DKKWSC 134
           E V MFE H   I C+  +P+     T SDD   +L+D   D++ +C
Sbjct: 626 ECVQMFEGHEADINCVRFYPSGDAFATGSDDATCRLFDLRADREVNC 486

 Score = 28.5 bits (62), Expect(2) = 3e-04,   Method: Composition-based stats.
 Identities = 18/69 (26%), Positives = 31/69 (44%)
 Frame = -3

Query: 164 DRTIKVWQLGSSSPNFTLEGHEKGVNCIDYYSGGDKPYLISGADDRLVKIWDYQNKTCVQ 223
           D T+ VW       +  L GH+  V+C+     G    L +G+ D  ++IW  + +    
Sbjct: 403 DYTVNVWDALKGMRSTILYGHDNRVSCLRISPDGTS--LCTGSWDYTLRIWA*ERE---- 242

Query: 224 TLEGHAQNV 232
              GH+ N+
Sbjct: 241 --RGHSSNI 221

 Score = 41.6 bits (96), Expect = 0.002,   Method: Composition-based stats.
 Identities = 19/53 (35%), Positives = 28/53 (52%), Gaps = 6/53 (11%)
 Frame = -2

Query: 221 CVQTLEGHAQNVSCASFHPELPIIITGSEDGTVRIW------HSSTYRLESTL 267
           CVQ  EGH  +++C  F+P      TGS+D T R++        + YR ES +
Sbjct: 623 CVQMFEGHEADINCVRFYPSGDAFATGSDDATCRLFDLRADREVNCYRKESII 465
>02090
          Length = 1841

 Score = 52.4 bits (124), Expect = 8e-07,   Method: Compositional matrix adjust.
 Identities = 26/91 (28%), Positives = 37/91 (40%)
 Frame = -3

Query: 166  TIKVWQLGSSSPNFTLEGHEKGVNCIDYYSGGDKPYLISGADDRLVKIWDYQNKTCVQTL 225
            T+ +W L + +P    E       C       D     S   D  + +WD  N+T V+  
Sbjct: 1689 TLSIWDLATPTPRIKAELTSSAPACYALAISPDGKVCFSCCSDGNIAVWDLHNQTLVRQF 1510

Query: 226  EGHAQNVSCASFHPELPIIITGSEDGTVRIW 256
            +GH    SC    P+   + TG  D TVR W
Sbjct: 1509 QGHTDGASCIDISPDGTKLWTGGLDNTVRSW 1417

 Score = 40.4 bits (93), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 32/112 (28%), Positives = 48/112 (42%)
 Frame = -3

Query: 148  IVINPKDNNQFASASLDRTIKVWQLGSSSPNFTLEGHEKGVNCIDYYSGGDKPYLISGAD 207
            + I+P     F+  S D  I VW L + +     +GH  G +CID    G K  L +G  
Sbjct: 1608 LAISPDGKVCFSCCS-DGNIAVWDLHNQTLVRQFQGHTDGASCIDISPDGTK--LWTGGL 1438

Query: 208  DRLVKIWDYQNKTCVQTLEGHAQNVSCASFHPELPIIITGSEDGTVRIWHSS 259
            D  V+ WD +    +Q  +  +Q  S   + P    +  G E   V + H S
Sbjct: 1437 DNTVRSWDLREGRQLQQHDFSSQIFS-LGYCPTGEWLAVGMESSNVEVLHHS 1285

 Score = 31.2 bits (69), Expect = 1.8,   Method: Compositional matrix adjust.
 Identities = 14/50 (28%), Positives = 23/50 (46%)
 Frame = -3

Query: 78   DMQIRVFNYNTLERVHMFEAHSDYIRCIAVHPTQPFILTSSDDMLIKLWD 127
            D  I V++ +    V  F+ H+D   CI + P    + T   D  ++ WD
Sbjct: 1563 DGNIAVWDLHNQTLVRQFQGHTDGASCIDISPDGTKLWTGGLDNTVRSWD 1414
>12960
          Length = 550

 Score = 51.6 bits (122), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 30/103 (29%), Positives = 49/103 (47%)
 Frame = +2

Query: 154 DNNQFASASLDRTIKVWQLGSSSPNFTLEGHEKGVNCIDYYSGGDKPYLISGADDRLVKI 213
           D+    +   D+++K+W         T  GH  G   +D    GD   + SG  D+ V +
Sbjct: 206 DSRYCMTCGSDKSVKLWNPHRELFLKTYIGH--GHEVLDAQGSGDNSQICSGGIDKTVVL 379

Query: 214 WDYQNKTCVQTLEGHAQNVSCASFHPELPIIITGSEDGTVRIW 256
           +D  +   ++    HA  V+C  F+ E  +I++GS D TVR W
Sbjct: 380 FDVASGQALRKYRDHAGTVNCVKFNEESTVILSGSLDNTVRAW 508
>02960
          Length = 1577

 Score = 50.8 bits (120), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 29/105 (27%), Positives = 52/105 (49%), Gaps = 8/105 (7%)
 Frame = +2

Query: 160 SASLDRTIKVWQLGSSSPNFTLEGHEKGVNCIDYY----SGGDKPYLISGADDRLVKIWD 215
           S S D T+++W     +   T+ GH   V C+ +     S G   + ++G+ D+   +W 
Sbjct: 530 SGSYDNTVRLWSTKGEAI-MTIPGHTSPVKCVAWIKHDESSGVSTF-VTGSHDQTALVWQ 703

Query: 216 YQNKT----CVQTLEGHAQNVSCASFHPELPIIITGSEDGTVRIW 256
           +Q +T    C  +  GHA +V C +  P+   + TGS D  +++W
Sbjct: 704 WQRETNEVDCRLSCRGHAASVDCVAVSPDSQQMCTGSWDKMLKLW 838

 Score = 42.4 bits (98), Expect = 8e-04,   Method: Compositional matrix adjust.
 Identities = 39/156 (25%), Positives = 71/156 (45%), Gaps = 9/156 (5%)
 Frame = +2

Query: 72   VVTGADDMQIRVFNYNTLERVHMFEAHSDYIRCIAVHPTQPFILTSSDDMLIKLWDWDKK 131
            VVT + D  +R+++ +T ++  + +  S  +  +A  P    ++T S D  ++L D    
Sbjct: 1001 VVTSSWDHSLRLWDLHTAQQTSLIQG-SKAVLDVAYSPLSHMLITGSADRHVRLVDP--- 1168

Query: 132  WSCSQ------VFEGHTHYVMQIVINPKDNNQFASASLDRTIKVWQLGSSSPNFTL---E 182
              CS+       F  HT +V  +  +P   + F S S D  +K+W   + SP  TL    
Sbjct: 1169 -RCSEGETVKCAFTSHTGWVTGVDWSPTREHLFLSGSYDNVLKLWD--TRSPKATLYDMN 1339

Query: 183  GHEKGVNCIDYYSGGDKPYLISGADDRLVKIWDYQN 218
             HE  +  +D+        L+SG  D  + ++ Y +
Sbjct: 1340 WHEDRILAVDW---SIPELLLSGGVDNKLHVFSYSS 1438

 Score = 39.7 bits (91), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 48/234 (20%), Positives = 97/234 (41%), Gaps = 9/234 (3%)
 Frame = +2

Query: 31  LASLYNGSVCVWNHETQTLVKTFEVCDLPVRAAKFVARK-----NWVVTGADDMQIRVFN 85
           L+  Y+ +V +W+ + + ++ T      PV+   ++        +  VTG+ D    V+ 
Sbjct: 527 LSGSYDNTVRLWSTKGEAIM-TIPGHTSPVKCVAWIKHDESSGVSTFVTGSHDQTALVWQ 703

Query: 86  Y----NTLERVHMFEAHSDYIRCIAVHPTQPFILTSSDDMLIKLWDWDKKWSCSQVFEGH 141
           +    N ++       H+  + C+AV P    + T S D ++KLW  D      Q  +  
Sbjct: 704 WQRETNEVDCRLSCRGHAASVDCVAVSPDSQQMCTGSWDKMLKLWSTDCNVDGDQSEDTE 883

Query: 142 THYVMQIVINPKDNNQFASASLDRTIKVWQLGSSSPNFTLEGHEKGVNCIDYYSGGDKPY 201
                     P    + A ++    +         P  TL GH + V+ + +    D   
Sbjct: 884 ---------RPSKKKKSAKSTTQTRV---------PVLTLSGHAEAVSAVRWL---DPHR 1000

Query: 202 LISGADDRLVKIWDYQNKTCVQTLEGHAQNVSCASFHPELPIIITGSEDGTVRI 255
           +++ + D  +++WD         ++G ++ V   ++ P   ++ITGS D  VR+
Sbjct: 1001VVTSSWDHSLRLWDLHTAQQTSLIQG-SKAVLDVAYSPLSHMLITGSADRHVRL 1159
>17266
          Length = 480

 Score = 48.9 bits (115), Expect = 8e-06,   Method: Composition-based stats.
 Identities = 38/149 (25%), Positives = 63/149 (42%), Gaps = 3/149 (2%)
 Frame = -1

Query: 105 IAVHPTQPFILTSSDDMLIKLWDWDKKWSCSQVFEGHTHYVMQIVINPKDNNQFASASLD 164
           +++ P     ++ + D   KLWD  +   C Q F GH   +  I   P + + FA+ S D
Sbjct: 441 LSLAPDMRTFVSGACDASAKLWDV-RDGMCKQTFSGHESDINAITYFP-NGHAFATGSDD 268

Query: 165 RTIKVWQLGSSSPNFTLEGHEK---GVNCIDYYSGGDKPYLISGADDRLVKIWDYQNKTC 221
            T +++ +  +     +  H+    G+  + +   G    L+ G DD    IWD   +  
Sbjct: 267 ATCRLFDI-RADQEIGMYSHDNIICGITSVAFSKSGR--LLLGGYDDFNCNIWDVLKQER 97

Query: 222 VQTLEGHAQNVSCASFHPELPIIITGSED 250
              L GH   VSC     +   + TGS D
Sbjct: 96  TGVLAGHDNRVSCLGVTEDGSAVATGSWD 10

 Score = 47.8 bits (112), Expect = 2e-05,   Method: Composition-based stats.
 Identities = 20/59 (33%), Positives = 32/59 (54%)
 Frame = -1

Query: 198 DKPYLISGADDRLVKIWDYQNKTCVQTLEGHAQNVSCASFHPELPIIITGSEDGTVRIW 256
           D    +SGA D   K+WD ++  C QT  GH  +++  ++ P      TGS+D T R++
Sbjct: 426 DMRTFVSGACDASAKLWDVRDGMCKQTFSGHESDINAITYFPNGHAFATGSDDATCRLF 250

 Score = 42.4 bits (98), Expect = 0.001,   Method: Composition-based stats.
 Identities = 33/140 (23%), Positives = 55/140 (39%), Gaps = 4/140 (2%)
 Frame = -1

Query: 154 DNNQFASASLDRTIKVWQLGSSSPNFTLEGHEKGVNCIDYYSGGDKPYLISGADDRLVKI 213
           D   F S + D + K+W +       T  GHE  +N I Y+  G      +G+DD   ++
Sbjct: 426 DMRTFVSGACDASAKLWDVRDGMCKQTFSGHESDINAITYFPNGHA--FATGSDDATCRL 253

Query: 214 WDYQNKTCVQTLEGHAQNVSCA----SFHPELPIIITGSEDGTVRIWHSSTYRLESTLNY 269
           +D +    +  +  H  N+ C     +F     +++ G +D    IW          L  
Sbjct: 252 FDIRADQEI-GMYSH-DNIICGITSVAFSKSGRLLLGGYDDFNCNIWDVLKQERTGVLAG 79

Query: 270 GMERVWCVASLRGSNNVALG 289
              RV C+      + VA G
Sbjct: 78  HDNRVSCLGVTEDGSAVATG 19

 Score = 33.1 bits (74), Expect = 0.48,   Method: Composition-based stats.
 Identities = 32/148 (21%), Positives = 61/148 (41%), Gaps = 4/148 (2%)
 Frame = -1

Query: 21  VDLHPTEPWMLASLYNGSVCVWNHETQTLVKTFEVCDLPVRAAKFVARKNWVVTGADDMQ 80
           + L P     ++   + S  +W+       +TF   +  + A  +    +   TG+DD  
Sbjct: 441 LSLAPDMRTFVSGACDASAKLWDVRDGMCKQTFSGHESDINAITYFPNGHAFATGSDDAT 262

Query: 81  IRVFNYNTLERVHMFEAHSDYIRC----IAVHPTQPFILTSSDDMLIKLWDWDKKWSCSQ 136
            R+F+    + + M+    D I C    +A   +   +L   DD    +WD  K+   + 
Sbjct: 261 CRLFDIRADQEIGMYS--HDNIICGITSVAFSKSGRLLLGGYDDFNCNIWDVLKQ-ERTG 91

Query: 137 VFEGHTHYVMQIVINPKDNNQFASASLD 164
           V  GH + V  + +  +D +  A+ S D
Sbjct: 90  VLAGHDNRVSCLGVT-EDGSAVATGSWD 10
>11493
          Length = 535

 Score = 48.5 bits (114), Expect = 1e-05,   Method: Composition-based stats.
 Identities = 33/162 (20%), Positives = 60/162 (37%), Gaps = 4/162 (2%)
 Frame = -2

Query: 97  AHSDYIRCIAVHPTQPFILTSSDDMLIKLWDWDKKWSCSQVFE----GHTHYVMQIVINP 152
           +H + +  + +     ++ T      +K+WD  +  + + V +       +Y+  + + P
Sbjct: 483 SHGEVVCAVTISNPTKYVYTGGKG-CVKVWDISQPGNKNPVSQLDCLQRDNYIRSVKLLP 307

Query: 153 KDNNQFASASLDRTIKVWQLGSSSPNFTLEGHEKGVNCIDYYSGGDKPYLISGADDRLVK 212
            D            + +W L S +P    E       C       D     S   D  + 
Sbjct: 306 -DGRTLIVGGEASNLSIWDLASPTPRIKAELTSAAPACYALAISPDSKVCFSCCSDGNIA 130

Query: 213 IWDYQNKTCVQTLEGHAQNVSCASFHPELPIIITGSEDGTVR 254
           +WD  N+  V+  +GH    SC    P+   + TG  D TVR
Sbjct: 129 VWDLHNEILVRQFQGHTDGASCIDISPDGSRLWTGGLDNTVR 4
>21105
          Length = 650

 Score = 46.6 bits (109), Expect = 4e-05,   Method: Composition-based stats.
 Identities = 30/120 (25%), Positives = 53/120 (44%), Gaps = 4/120 (3%)
 Frame = +1

Query: 141 HTHYVMQIVINPKDNNQFASASLDRTIKVWQLGSSSPNFTLEGHEKGVNCIDYYSGGDKP 200
           H H  M I I         +A  DR I+ +   +      +  H   V  +     G   
Sbjct: 85  HQHPTMPITI---------TAHEDRHIRFFDNNTGKLIHAMVAHLDSVTSLAVDPNG--L 231

Query: 201 YLISGADDRLVKIWDYQNKTCVQTLEGHA----QNVSCASFHPELPIIITGSEDGTVRIW 256
           YL+SG+ D  +++W+  +KTCVQ +  H     +++   +FHP+ P I +   D   +++
Sbjct: 232 YLLSGSHDCSIRLWNLDSKTCVQEITSHRKKFDESIHDVAFHPQKPYIASAGADALAKVF 411

 Score = 35.8 bits (81), Expect = 0.090,   Method: Composition-based stats.
 Identities = 23/107 (21%), Positives = 50/107 (46%), Gaps = 4/107 (3%)
 Frame = +1

Query: 24  HPTEPWMLASLYNGSVCVWNHETQTLVKTFEVCDLPVRAAKFVARKNWVVTGADDMQIRV 83
           HPT P  + +  +  +  +++ T  L+         V +        ++++G+ D  IR+
Sbjct: 91  HPTMPITITAHEDRHIRFFDNNTGKLIHAMVAHLDSVTSLAVDPNGLYLLSGSHDCSIRL 270

Query: 84  FNYNTLERVHMFEAH----SDYIRCIAVHPTQPFILTSSDDMLIKLW 126
           +N ++   V    +H     + I  +A HP +P+I ++  D L K++
Sbjct: 271 WNLDSKTCVQEITSHRKKFDESIHDVAFHPQKPYIASAGADALAKVF 411
>15337
          Length = 860

 Score = 45.4 bits (106), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 21/79 (26%), Positives = 39/79 (49%)
 Frame = -1

Query: 65  FVARKNWVVTGADDMQIRVFNYNTLERVHMFEAHSDYIRCIAVHPTQPFILTSSDDMLIK 124
           F     ++     D  +RVFNYN++E +   +++   + C+   P   +I+T  +D L+ 
Sbjct: 305 FSPCSRYLAVVGQDGHLRVFNYNSMELIGTMKSYFGGLLCVCWSPDGKYIVTGGEDDLVT 126

Query: 125 LWDWDKKWSCSQVFEGHTH 143
           +W + +K     V  GH H
Sbjct: 125 VWSFHEK---RVVCRGHGH 78

 Score = 34.3 bits (77), Expect = 0.24,   Method: Compositional matrix adjust.
 Identities = 14/56 (25%), Positives = 29/56 (51%)
 Frame = -1

Query: 201 YLISGADDRLVKIWDYQNKTCVQTLEGHAQNVSCASFHPELPIIITGSEDGTVRIW 256
           YL     D  +++++Y +   + T++ +   + C  + P+   I+TG ED  V +W
Sbjct: 287 YLAVVGQDGHLRVFNYNSMELIGTMKSYFGGLLCVCWSPDGKYIVTGGEDDLVTVW 120

 Score = 34.3 bits (77), Expect = 0.26,   Method: Compositional matrix adjust.
 Identities = 20/80 (25%), Positives = 37/80 (46%)
 Frame = -1

Query: 158 FASASLDRTIKVWQLGSSSPNFTLEGHEKGVNCIDYYSGGDKPYLISGADDRLVKIWDYQ 217
            A    D  ++V+   S     T++ +  G+ C+ +   G   Y+++G +D LV +W + 
Sbjct: 284 LAVVGQDGHLRVFNYNSMELIGTMKSYFGGLLCVCWSPDGK--YIVTGGEDDLVTVWSFH 111

Query: 218 NKTCVQTLEGHAQNVSCASF 237
            K  V    GH   V+  +F
Sbjct: 110 EKRVVCRGHGHKSWVNVVAF 51
>13278
          Length = 870

 Score = 45.1 bits (105), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 25/77 (32%), Positives = 41/77 (53%)
 Frame = +1

Query: 151 NPKDNNQFASASLDRTIKVWQLGSSSPNFTLEGHEKGVNCIDYYSGGDKPYLISGADDRL 210
           NP  +   ASAS D T+++W++       TL  H++ V  + +    D  YL SG+ D+ 
Sbjct: 100 NPNTSLILASASFDSTVRLWEVERGLCLHTLTKHQEPVYSVAF--SPDGKYLASGSFDKC 273

Query: 211 VKIWDYQNKTCVQTLEG 227
           V IW+ Q  + V + +G
Sbjct: 274 VHIWNVQTGSLVHSYKG 324
>16105
          Length = 960

 Score = 43.1 bits (100), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 36/124 (29%), Positives = 58/124 (46%), Gaps = 8/124 (6%)
 Frame = -2

Query: 140 GHTHYVMQIVINPKDNNQFASASLDRTIKVWQLGSSS-------PNFTLEGHEKGVNCID 192
           GH   V+ I   P ++N  ASAS D T+KVWQ+  S        P   L GH+K    I 
Sbjct: 581 GHKGAVLDIQWCPHNDNVIASASDDCTVKVWQIPDSGLVTNLTDPVVDLVGHQKRCCLIV 402

Query: 193 YYSGGDKPYLISGADDRLVKIWDYQNKTCVQTLEGHAQN-VSCASFHPELPIIITGSEDG 251
           ++       + +GAD++++  W+    T    LE    + + C SF+     ++   +D 
Sbjct: 401 WHPSAQNVLVSAGADNKIL-FWNV--GTGEPMLEVDVPDMIYCMSFNFNGSRLVCTCKDK 231

Query: 252 TVRI 255
            +RI
Sbjct: 230 KLRI 219
>01805
          Length = 2124

 Score = 43.1 bits (100), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 36/148 (24%), Positives = 73/148 (49%), Gaps = 5/148 (3%)
 Frame = -1

Query: 114 ILTSSDDMLIKLWDWDKKWSCSQVFEGHTHYVMQIVINPKDNNQFASASLDRTIKVWQLG 173
           + ++S D  + LWD  +    +  F  H+  V     +P++     + S D T+KV    
Sbjct: 528 LASASADTTVALWDLSEG-KMAMNFTQHSREVQCCNWHPQEEQTLLTGSFDNTVKVVDCR 352

Query: 174 SSSP---NFTLEGH-EKGVNCIDYYSGGDKPYLISGADDRLVKIWDYQNKTCVQTLEGHA 229
           S+     ++T+EG  EK V     ++  +   L++  D  +V  +D +++  V ++  H+
Sbjct: 351 SAETCHKSWTVEGEVEKAV-----WNHHNPLQLLACTDKGMVYCFDIRHEKPVFSVGAHS 187

Query: 230 QNVSCASFHPELP-IIITGSEDGTVRIW 256
             V+      ++P ++IT SED T+++W
Sbjct: 186 SCVTGVCLSSQIPGLMITTSEDKTMKVW 103

 Score = 39.7 bits (91), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 31/121 (25%), Positives = 49/121 (40%), Gaps = 21/121 (17%)
 Frame = -1

Query: 156 NQFASASLDRTIKVWQLG---SSSPNFTL-----------------EGHEKGVNCIDYYS 195
           N  A  S++  I++W L    S  P  TL                  GH + V  + +  
Sbjct: 723 NFVAIGSMEPVIEIWDLDIMESVGPTLTLGSKPKKTKKKMKQKESVTGHTQAVLDLSWNR 544

Query: 196 GGDKPYLISGADDRLVKIWDYQNKTCVQTLEGHAQNVSCASFHP-ELPIIITGSEDGTVR 254
              +  L S + D  V +WD            H++ V C ++HP E   ++TGS D TV+
Sbjct: 543 NA-RHVLASASADTTVALWDLSEGKMAMNFTQHSREVQCCNWHPQEEQTLLTGSFDNTVK 367

Query: 255 I 255
           +
Sbjct: 366 V 364
>21960
          Length = 756

 Score = 42.7 bits (99), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 21/67 (31%), Positives = 34/67 (50%), Gaps = 1/67 (1%)
 Frame = +1

Query: 194 YSGGDKPYLISGADDRLVKIWDYQNKTCVQTLEGH-AQNVSCASFHPELPIIITGSEDGT 252
           + G    ++ISG+DD  +  WD   +     ++G  A  V+C   HP +P++ T   D  
Sbjct: 385 FFGPHSEHIISGSDDGNIFYWDKNTEAVTNFMKGDDAGVVNCLEQHPTMPVLATSGLDHN 564

Query: 253 VRIWHSS 259
           V+IW  S
Sbjct: 565 VKIWTPS 585

 Score = 37.0 bits (84), Expect = 0.035,   Method: Compositional matrix adjust.
 Identities = 22/68 (32%), Positives = 33/68 (48%), Gaps = 2/68 (2%)
 Frame = +1

Query: 61  RAAKFVARKNWVVTGADDMQIRVFNYNTLERVHMFEAHSD--YIRCIAVHPTQPFILTSS 118
           R   F      +++G+DD  I  ++ NT E V  F    D   + C+  HPT P + TS 
Sbjct: 376 RVNFFGPHSEHIISGSDDGNIFYWDKNT-EAVTNFMKGDDAGVVNCLEQHPTMPVLATSG 552

Query: 119 DDMLIKLW 126
            D  +K+W
Sbjct: 553 LDHNVKIW 576
>27806
          Length = 419

 Score = 42.4 bits (98), Expect = 8e-04,   Method: Compositional matrix adjust.
 Identities = 17/57 (29%), Positives = 29/57 (50%)
 Frame = -1

Query: 200 PYLISGADDRLVKIWDYQNKTCVQTLEGHAQNVSCASFHPELPIIITGSEDGTVRIW 256
           P + + + D   +I+  +   CV T  GH  +V+   FHP   +++T S D T  +W
Sbjct: 386 PIIGTASADHTARIYSIETGACVLTYGGHQGSVNAVRFHPGQDLVLTASGDHTAHVW 216
>10162
          Length = 1629

 Score = 42.4 bits (98), Expect = 9e-04,   Method: Compositional matrix adjust.
 Identities = 54/266 (20%), Positives = 105/266 (39%), Gaps = 40/266 (15%)
 Frame = +3

Query: 30  MLASLYNGSVCVWNHETQ--TLVKTFEVCDLPVRAAKFVARKNWVVTGADDMQIRVFNYN 87
           +LA    G V +W   +Q  + +K  +    P    K +    +V  G  D  +++++  
Sbjct: 72  LLAGTQGGEVWLWQVPSQDYSKMKMLQSHGQPSLCGKILPNGKYVCVGYSDGVVKLWDLK 251

Query: 88  TLERVHMFEAHS-----------------------------DYIRCIAVHPTQPFILTSS 118
           T   VH ++ HS                               I C+        I++  
Sbjct: 252 TGTAVHTWQ-HSVMPEEEMPERNSSDEEDGEEVEVEREEDTVAILCVDCSADNALIMSGC 428

Query: 119 DDMLIKLWD-----WDKKWSC--SQVFEGHTHYVMQIVINPKDNNQFASASLDRTIKVWQ 171
            D   K+++         ++C  SQ  +   + V  +   P  +   A+A+   +++VW 
Sbjct: 429 ADATAKVFNVSSGKLXSAFNCAASQDSQDKDNSVESVAFCPV-SPYAATATNSGSVQVWD 605

Query: 172 LGSSSPNFTLEGHEKGVNCIDYYSGGDKPYLISGADDRLVKIWDYQNKTCVQTLEGHAQN 231
           L +S    + + H +GV  + + S      L +   D ++++WD ++      L GHA+N
Sbjct: 606 LPTSVARHSFQ-HPEGVCKLQWSS--STALLYTACLDGVMRVWDARSGASKAVLTGHARN 776

Query: 232 VSCASFH--PELPIIITGSEDGTVRI 255
                F    +   +++GSEDGT R+
Sbjct: 777 SCILDFDVTRDGTCLVSGSEDGTARV 854

 Score = 29.6 bits (65), Expect = 5.1,   Method: Compositional matrix adjust.
 Identities = 16/62 (25%), Positives = 27/62 (43%), Gaps = 2/62 (3%)
 Frame = +3

Query: 197 GDKPYLISGADDRLVKIWDY--QNKTCVQTLEGHAQNVSCASFHPELPIIITGSEDGTVR 254
           G    L++G     V +W    Q+ + ++ L+ H Q   C    P    +  G  DG V+
Sbjct: 57  GGAHVLLAGTQGGEVWLWQVPSQDYSKMKMLQSHGQPSLCGKILPNGKYVCVGYSDGVVK 236

Query: 255 IW 256
           +W
Sbjct: 237 LW 242
>26107
          Length = 1338

 Score = 40.8 bits (94), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 42/166 (25%), Positives = 74/166 (44%), Gaps = 10/166 (6%)
 Frame = -3

Query: 65   FVARKNWVVTGADDMQIRVFNYNTLERVHMFEAHSDYIRCIAVHPTQPFILTS-SDDMLI 123
            +++  +  +T + D  + +++  T  +V  F  H   +R +A  P+ P    S + D  I
Sbjct: 1063 WISNDSQCLTASGDQTVALWDVETTTKVTTFIGHKCSVRSVASCPSSPAQCASGARDGHI 884

Query: 124  KLWDW--DKK---WSCSQVFEGHTHYVMQIVINPKDNNQFASASLDRTIKVWQLGSSSPN 178
             LWD   +KK     CSQV +          + P+  +Q   A   R  +     ++ P 
Sbjct: 883  MLWDSRVNKKREHQPCSQVHQ----------VCPQSGHQSKPAKHRRIHR-----AAGPK 749

Query: 179  FTLEGHEKGVNCIDYYSGGDKPYLISGADDRLVKIWD----YQNKT 220
              ++  ++ V C+ Y +  D   + SGA+D  VK+WD    Y N T
Sbjct: 748  GVMDT-QQSVTCVLYQT--DNLIISSGANDGCVKMWDTRKWYTNTT 620

 Score = 38.5 bits (88), Expect = 0.013,   Method: Compositional matrix adjust.
 Identities = 25/92 (27%), Positives = 39/92 (42%), Gaps = 2/92 (2%)
 Frame = -3

Query: 169  VWQLGSSSPNF-TLEGHEKGVNCIDYYSGGDKPYLISGADDRLVKIWDYQNKTCVQTLEG 227
             W+ G  SP       H   V   DY    +    ++ + D+ V +WD +  T V T  G
Sbjct: 1138 AWRYGQDSPTVHRWXAHNNAV--FDYSWISNDSQCLTASGDQTVALWDVETTTKVTTFIG 965

Query: 228  HAQNVSCASFHPELPI-IITGSEDGTVRIWHS 258
            H  +V   +  P  P    +G+ DG + +W S
Sbjct: 964  HKCSVRSVASCPSSPAQCASGARDGHIMLWDS 869

 Score = 32.3 bits (72), Expect = 0.99,   Method: Compositional matrix adjust.
 Identities = 19/71 (26%), Positives = 35/71 (49%)
 Frame = -3

Query: 101 YIRCIAVHPTQPFILTSSDDMLIKLWDWDKKWSCSQVFEGHTHYVMQIVINPKDNNQFAS 160
           ++RC A+ P   ++L+ S      +W+ DK         GHT  V  +     D  + A+
Sbjct: 415 FVRC-AISPDGKYLLSGSGRNTGVIWEVDKPNKRPLFLIGHTEDVSAVDWCSTDVCKLAT 239

Query: 161 ASLDRTIKVWQ 171
            S DR++++W+
Sbjct: 238 VSDDRSLRIWR 206
>19863
          Length = 502

 Score = 40.8 bits (94), Expect = 0.002,   Method: Composition-based stats.
 Identities = 20/56 (35%), Positives = 32/56 (57%)
 Frame = +1

Query: 202 LISGADDRLVKIWDYQNKTCVQTLEGHAQNVSCASFHPELPIIITGSEDGTVRIWH 257
           L+SG+ D  + +WD +N      L+GHA  V+   F  +   +++ S D TVRIW+
Sbjct: 16  LVSGSSDMSIVVWDVENGVQKLRLQGHAGWVNDVHFSQDQCWLLSCSNDNTVRIWN 183

 Score = 39.3 bits (90), Expect = 0.007,   Method: Composition-based stats.
 Identities = 22/77 (28%), Positives = 38/77 (49%)
 Frame = +1

Query: 154 DNNQFASASLDRTIKVWQLGSSSPNFTLEGHEKGVNCIDYYSGGDKPYLISGADDRLVKI 213
           D  Q  S S D +I VW + +      L+GH   VN  D +   D+ +L+S ++D  V+I
Sbjct: 4   DGLQLVSGSSDMSIVVWDVENGVQKLRLQGHAGWVN--DVHFSQDQCWLLSCSNDNTVRI 177

Query: 214 WDYQNKTCVQTLEGHAQ 230
           W+ +    +  +  H +
Sbjct: 178 WNIEESDQIPIVMEHKR 228
>27270
          Length = 1078

 Score = 40.4 bits (93), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 34/119 (28%), Positives = 57/119 (47%), Gaps = 16/119 (13%)
 Frame = +2

Query: 78  DMQIRVFNYNTLERVHMFEAHSDY---IRCIAVHPTQPFILTSSDDMLIKLWDWDKKWSC 134
           D  +  +N NTL  +  ++A S     + C+ +  +   +   + D  IK+WD   K + 
Sbjct: 335 DGHVIGWNVNTLHMIEKWKATSGRHHGVHCVCLCSSSRLL---TADHTIKMWDLTTK-NV 502

Query: 135 SQVFEGHTHYVMQI--VINPK-------DNNQ----FASASLDRTIKVWQLGSSSPNFT 180
            Q F GH+  V+++  V+ P        D+N     F++A+ DRTI VW+  S S   T
Sbjct: 503 LQEFSGHSTEVIKLLPVLKPSSEQNDIGDSNLACYVFSAAAADRTINVWRCDSESSQAT 679

 Score = 28.9 bits (63), Expect = 9.4,   Method: Compositional matrix adjust.
 Identities = 24/97 (24%), Positives = 39/97 (40%), Gaps = 3/97 (3%)
 Frame = +2

Query: 139 EGHTHYVMQIVINPKDNNQFASASLDRTIKVWQLGS---SSPNFTLEGHEKGVNCIDYYS 195
           +GH+  V  +     D     S+SLD  +  W + +           G   GV+C+   S
Sbjct: 263 KGHSKAVTDMCWRA-DGRTLYSSSLDGHVIGWNVNTLHMIEKWKATSGRHHGVHCVCLCS 439

Query: 196 GGDKPYLISGADDRLVKIWDYQNKTCVQTLEGHAQNV 232
                 L++   D  +K+WD   K  +Q   GH+  V
Sbjct: 440 ---SSRLLTA--DHTIKMWDLTTKNVLQEFSGHSTEV 535
>08679
          Length = 2028

 Score = 40.4 bits (93), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 27/81 (33%), Positives = 39/81 (48%), Gaps = 6/81 (7%)
 Frame = -3

Query: 101  YIRCIAVHPTQP-FILTSSDDMLIKLWDWDKKWSCSQVFEG-----HTHYVMQIVINPKD 154
            Y+R ++VHPT P F +T+  DM   +WD  +K S S+  E      H   V     +P  
Sbjct: 1537 YLRSVSVHPTNPHFFVTAGSDMKXSVWDL-RKLSASKGNEPLHSMMHGKTVSSAYFSPLT 1361

Query: 155  NNQFASASLDRTIKVWQLGSS 175
              +  S S D T+ V+   SS
Sbjct: 1360 GARILSCSADDTLNVFNCSSS 1298
>01462
          Length = 995

 Score = 40.0 bits (92), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 18/55 (32%), Positives = 29/55 (52%)
 Frame = +2

Query: 202 LISGADDRLVKIWDYQNKTCVQTLEGHAQNVSCASFHPELPIIITGSEDGTVRIW 256
           L +GA DR + +WD +    +  +EGH   +       +    ++ SEDGTVR+W
Sbjct: 242 LYAGAGDRKIHVWDIEAGQYLNAMEGHKDYIHKVVMKNDAQECVSASEDGTVRMW 406

 Score = 33.1 bits (74), Expect = 0.46,   Method: Compositional matrix adjust.
 Identities = 14/53 (26%), Positives = 29/53 (54%)
 Frame = +2

Query: 75  GADDMQIRVFNYNTLERVHMFEAHSDYIRCIAVHPTQPFILTSSDDMLIKLWD 127
           GA D +I V++    + ++  E H DYI  + +       +++S+D  +++WD
Sbjct: 251 GAGDRKIHVWDIEAGQYLNAMEGHKDYIHKVVMKNDAQECVSASEDGTVRMWD 409

 Score = 31.2 bits (69), Expect = 1.9,   Method: Compositional matrix adjust.
 Identities = 14/41 (34%), Positives = 24/41 (58%)
 Frame = +2

Query: 136 QVFEGHTHYVMQIVINPKDNNQFASASLDRTIKVWQLGSSS 176
              EGH  Y+ ++V+   D  +  SAS D T+++W + SS+
Sbjct: 305 NAMEGHKDYIHKVVMK-NDAQECVSASEDGTVRMWDIRSST 424
>01249
          Length = 1743

 Score = 38.9 bits (89), Expect = 0.010,   Method: Compositional matrix adjust.
 Identities = 32/117 (27%), Positives = 57/117 (48%), Gaps = 16/117 (13%)
 Frame = -1

Query: 157  QFASASLDRTIKVWQLGSSSPNFTLEGHEKGVNCIDYYSGGDKP--YLISGADD------ 208
            + AS+S D T K+W + S +   T+  +E GV C+      DK   +L++G D+      
Sbjct: 1164 RVASSSSDGTCKLWDMLSGALLRTMV-YETGVGCLIM----DKQEHFLLAGLDNGDILCS 1000

Query: 209  --------RLVKIWDYQNKTCVQTLEGHAQNVSCASFHPELPIIITGSEDGTVRIWH 257
                      V +  +  K   + L+GH+  V+C +F  +   + +GS++G V IW+
Sbjct: 999  PLFGQISQSEVFVSKHTTKAGERVLQGHSDAVTCLAFSSDGQRLASGSQNGKVIIWN 829

 Score = 28.9 bits (63), Expect = 8.5,   Method: Compositional matrix adjust.
 Identities = 54/307 (17%), Positives = 113/307 (36%), Gaps = 19/307 (6%)
 Frame = -1

Query: 81   IRVFNYNTLERVHMFEAHSDYIRCIAVHPTQPFILTSSDDMLIKLWDWDKKWSCSQ--VF 138
            +  ++  +   V  F+  +    C+ +      +  + +  +I +W   KK       V 
Sbjct: 1671 VAAWDIQSRSSVRTFKGQALAAGCLCLRCGHTLLGAAQNKPVIHVWPLSKKDESQHKIVC 1492

Query: 139  EGHTHYVMQIVINPKDNNQFASASLDRTIKVWQLGSSSPNFTLEGHEKGVNCIDYYSGGD 198
             G    V  +V++P  +  F  AS+   I +W++   S    L    +    I +   G 
Sbjct: 1491 PGK---VSVLVVSP--DGLFCLASISEKIYIWEMTGGSLVGLLSDFNEATK-IQFTDDGS 1330

Query: 199  KPYLISGADDRLVKIWDYQNKTCV-----------QTLEGHAQNVSCASFHPELPI--II 245
            + ++++ +   L  IWD+                 +T+  H++ ++        P   + 
Sbjct: 1329 Q-FVVATSSGHL-NIWDFARVVTTTSQRARGLKPGRTINAHSEPITGLHVGCGGPAARVA 1156

Query: 246  TGSEDGTVRIWHSSTYRLESTLNYGMERVWCVASLRGSNNVALGYDEGSIIVKLGREEPA 305
            + S DGT ++W   +  L  T+ Y    V C+   +  + +  G D G I+       P 
Sbjct: 1155 SSSSDGTCKLWDMLSGALLRTMVY-ETGVGCLIMDKQEHFLLAGLDNGDILC-----SPL 994

Query: 306  MSMDANGKIIWAKHSEVQQANLKAMGDTEIKDGERLPLAVKDMGSCEIYPQTIQH----N 361
                +  ++  +KH+               K GER+     D  +C  +    Q     +
Sbjct: 993  FGQISQSEVFVSKHT--------------TKAGERVLQGHSDAVTCLAFSSDGQRLASGS 856

Query: 362  PNGRFVV 368
             NG+ ++
Sbjct: 855  QNGKVII 835
>19498
          Length = 903

 Score = 38.1 bits (87), Expect = 0.014,   Method: Compositional matrix adjust.
 Identities = 25/132 (18%), Positives = 62/132 (46%), Gaps = 9/132 (6%)
 Frame = -1

Query: 71  WVVTGADDMQIRVFNYNTL-ERVHMFEAHSDYIRCIAVHPTQPFILTSSDDMLIKLW--- 126
           W+ + + D  I V+N     E+V +   H+  ++ +   P   ++ + SDD  +++W   
Sbjct: 567 WLASCSVDNTIVVWNALKFSEQVAVIRGHAGMVKGVTWDPVGRYLASQSDDKTLRVWRTS 388

Query: 127 DWDKKWSCSQVFE--GHTHYVMQIVINPKDNNQFASASLDR---TIKVWQLGSSSPNFTL 181
           DW ++      F+  G T +V+++  +P  N+  ++ +++    T ++ +      +   
Sbjct: 387 DWKEETCVKSCFKECGGTTHVLRLNWSPDGNHVVSAHAMNNAXPTAQIIERNGWGTSLDF 208

Query: 182 EGHEKGVNCIDY 193
            GH K +  + +
Sbjct: 207 VGHRKAITVVRF 172

 Score = 37.7 bits (86), Expect = 0.022,   Method: Compositional matrix adjust.
 Identities = 31/131 (23%), Positives = 60/131 (45%), Gaps = 17/131 (12%)
 Frame = -1

Query: 154 DNNQF-ASASLDRTIKVWQLG-------SSSPNFTLEGHEKGVNCIDYYSGG-------- 197
           +N +F AS   D+ I +WQ+        S   N T+  H + V  +  ++G         
Sbjct: 756 ENGKFLASGGDDKLIMIWQISRGFGSGKSFGSNVTILEHWRSVATLRGHAGDVLDLAWSP 577

Query: 198 DKPYLISGADDRLVKIWD-YQNKTCVQTLEGHAQNVSCASFHPELPIIITGSEDGTVRIW 256
              +L S + D  + +W+  +    V  + GHA  V   ++ P    + + S+D T+R+W
Sbjct: 576 QDLWLASCSVDNTIVVWNALKFSEQVAVIRGHAGMVKGVTWDPVGRYLASQSDDKTLRVW 397

Query: 257 HSSTYRLESTL 267
            +S ++ E+ +
Sbjct: 396 RTSDWKEETCV 364
>20662
          Length = 1220

 Score = 38.1 bits (87), Expect = 0.016,   Method: Compositional matrix adjust.
 Identities = 20/51 (39%), Positives = 30/51 (58%), Gaps = 1/51 (1%)
 Frame = +2

Query: 78  DMQIRVFNYNTLERVHMFEAHSDYIRCIAVHPTQP-FILTSSDDMLIKLWD 127
           D  I+V+N + L  ++ + AHSD +  +  HPT+P   L+ S D  I LWD
Sbjct: 449 DHGIKVWNTD-LTSLYTYRAHSDIVWDVQCHPTEPALFLSCSQDGKIVLWD 598

 Score = 37.4 bits (85), Expect = 0.025,   Method: Compositional matrix adjust.
 Identities = 38/159 (23%), Positives = 67/159 (42%), Gaps = 11/159 (6%)
 Frame = +2

Query: 98  HSDYIRCIAVHPTQPFILTSSDDMLIKLWDWDKKWSCSQVFEGHTHYVMQIVINPKDNNQ 157
           H D    ++++      L++S D  IK+W+ D   +    +  H+  V  +  +P +   
Sbjct: 383 HDDMTASVSINSDXSHYLSASYDHGIKVWNTDL--TSLYTYRAHSDIVWDVQCHPTEPAL 556

Query: 158 FASASLDRTIKVWQLGSSSPNFTLEGHEKGV--NCIDY-------YSGGDKPYLISGADD 208
           F S S D  I +W +  S P   L     G    C+ +       Y+ GD+   +S  D 
Sbjct: 557 FLSCSQDGKIVLWDVRESKPATCLPKCSSGFKPTCVQWQPNARNMYAVGDEGGHVSVQDL 736

Query: 209 RLV--KIWDYQNKTCVQTLEGHAQNVSCASFHPELPIII 245
           R+V  K   YQ+         H + V+  +F P+ P ++
Sbjct: 737 RMVVEKNVSYQS---------HNRVVTRLAFCPQRPSML 826
>38177
          Length = 430

 Score = 37.7 bits (86), Expect = 0.019,   Method: Composition-based stats.
 Identities = 20/74 (27%), Positives = 34/74 (45%)
 Frame = +3

Query: 36  NGSVCVWNHETQTLVKTFEVCDLPVRAAKFVARKNWVVTGADDMQIRVFNYNTLERVHMF 95
           +G   +WN  T       +  D+ VRA ++     W+VT      I+ +  N +  V MF
Sbjct: 51  SGEFTLWNGLTFNFETILQAHDVSVRAMRWSNHDQWMVTADHSGYIKYWQSN-MNNVKMF 227

Query: 96  EAHSDYIRCIAVHP 109
           + H + IR + + P
Sbjct: 228 QGHKEPIRGVRLAP 269
>04524
          Length = 1340

 Score = 37.7 bits (86), Expect = 0.022,   Method: Compositional matrix adjust.
 Identities = 23/78 (29%), Positives = 40/78 (51%), Gaps = 1/78 (1%)
 Frame = -1

Query: 181  LEGHEKGVNCIDYYSGGDKPYLISGADDRLVKIWDYQNKTCVQT-LEGHAQNVSCASFHP 239
            L GH   V  +D    G + ++++   D  +++  + N   + T   GH Q V+C  +  
Sbjct: 1040 LLGHLSMV--LDVCLTGREGHVVTCDRDEKIRVSQFPNAYNIHTYCLGHTQFVNCLVYVE 867

Query: 240  ELPIIITGSEDGTVRIWH 257
            E  ++I+GS D TVR W+
Sbjct: 866  EFRVLISGSGDCTVRAWN 813
>20271
          Length = 567

 Score = 37.7 bits (86), Expect = 0.022,   Method: Compositional matrix adjust.
 Identities = 25/85 (29%), Positives = 41/85 (48%), Gaps = 7/85 (8%)
 Frame = -1

Query: 95  FEAHSDYIRCIAVHPT------QPFILTSSDDMLIKLWDW-DKKWSCSQVFEGHTHYVMQ 147
           +E H   I  I  H         PF LT+S D  +KLW+  ++K+ CS  FE ++ YV  
Sbjct: 297 YEGHQGPITAIDTHHAAGQIDFSPFFLTASFDWTVKLWNIKEQKYVCS--FEDNSDYVSD 124

Query: 148 IVINPKDNNQFASASLDRTIKVWQL 172
           +  +P +   F+   +   + +W L
Sbjct: 123 VQWSPTNPALFSCVDIMGRLDLWHL 49
>06576
          Length = 1547

 Score = 37.4 bits (85), Expect = 0.029,   Method: Compositional matrix adjust.
 Identities = 24/103 (23%), Positives = 49/103 (47%), Gaps = 9/103 (8%)
 Frame = -2

Query: 77   DDMQIRVFNYNTLERVHMFEAHSDYIRCIAVHPTQPF--------ILTSSDDMLIKLWDW 128
            +D+ I+  +Y+ ++ V M +     + C+A  P+              + DD  ++++  
Sbjct: 1294 EDIDIQGLDYSVVKDVQMDQG----VSCLAWSPSTSLSSLDKHLCFAAACDDHSVRVFTS 1127

Query: 129  D-KKWSCSQVFEGHTHYVMQIVINPKDNNQFASASLDRTIKVW 170
            D K  + + V +GHT +V  +  +P + +Q  S   D T +VW
Sbjct: 1126 DLKTTNKTHVVKGHTDFVNSVTFSPTEEDQVXSTGDDLTCRVW 998
>21921
          Length = 1341

 Score = 36.6 bits (83), Expect = 0.043,   Method: Compositional matrix adjust.
 Identities = 30/106 (28%), Positives = 45/106 (42%), Gaps = 7/106 (6%)
 Frame = -1

Query: 190 CIDYYSGGDKPYLISGADD-----RLVKIWDYQNKTCVQTL--EGHAQNVSCASFHPELP 242
           C+D Y    +  +    D      +L K  D +     Q L  +GH   V      P   
Sbjct: 621 CLDLYLCARQRKMKMNVDPQDLLPKLPKPKDLRPFPTTQALVYKGHTGIVRSICPDPTGQ 442

Query: 243 IIITGSEDGTVRIWHSSTYRLESTLNYGMERVWCVASLRGSNNVAL 288
            +++GS+DGT+R W  S+ R   TL  G     CV S+  + N +L
Sbjct: 441 WLVSGSDDGTIRFWEVSSGRCMKTLQVGG----CVTSVAWNPNPSL 316

 Score = 30.0 bits (66), Expect = 4.4,   Method: Compositional matrix adjust.
 Identities = 17/74 (22%), Positives = 35/74 (47%)
 Frame = -1

Query: 94  MFEAHSDYIRCIAVHPTQPFILTSSDDMLIKLWDWDKKWSCSQVFEGHTHYVMQIVINPK 153
           +++ H+  +R I   PT  ++++ SDD  I+ W+         +  G    V  +  NP 
Sbjct: 498 VYKGHTGIVRSICPDPTGQWLVSGSDDGTIRFWEVSSGRCMKTLQVGGC--VTSVAWNPN 325

Query: 154 DNNQFASASLDRTI 167
            +    +A+L+ T+
Sbjct: 324 PSLCVVAATLNTTV 283
>03044
          Length = 1952

 Score = 36.6 bits (83), Expect = 0.045,   Method: Compositional matrix adjust.
 Identities = 38/173 (21%), Positives = 69/173 (39%), Gaps = 10/173 (5%)
 Frame = -2

Query: 93   HMFEAHSDYIRCIAVHPT---QPFILTSSDDMLIKLWDWD-KKWSCSQVFEGHTHYVMQI 148
            +M E HS  ++ +  H     +  +  S +D  +K++  +  KW  +     H   V  I
Sbjct: 1813 NMAEKHSFGVKAVTCHAASGDRNGLALSLNDHEVKIYKKNGSKWQETDTLGEHGQRVTGI 1634

Query: 149  VINPKDNNQFASASLDRTIKVW--QLGSSSPNFTLEGHEKGVNCIDYYSGGDKPYLISGA 206
               PK +N+  +   DR   VW  Q G   P+  +    +   C+ +    +K     G+
Sbjct: 1633 DWAPK-SNRIVTCGADRNAYVWTYQDGKWQPHLVILRINRAATCVKWSPEENK--FAVGS 1463

Query: 207  DDRLVKIWDYQNK----TCVQTLEGHAQNVSCASFHPELPIIITGSEDGTVRI 255
              RL+ +  Y+ +          +     V+C  +HP   +I  GS D   R+
Sbjct: 1462 SARLISVSYYEEEHRWWVSKHIKKPIRSTVTCLDWHPNNILIAAGSTDFKARV 1304
>19140
          Length = 573

 Score = 36.6 bits (83), Expect = 0.052,   Method: Compositional matrix adjust.
 Identities = 19/59 (32%), Positives = 29/59 (49%), Gaps = 2/59 (3%)
 Frame = -3

Query: 219 KTC--VQTLEGHAQNVSCASFHPELPIIITGSEDGTVRIWHSSTYRLESTLNYGMERVW 275
           +TC  +  L+GH  NV     + +    ++GS DGT+R+W     R  +T     E VW
Sbjct: 523 RTCHKLMKLKGHTDNVKALVLNRDGTQCLSGSSDGTIRLWSLGQQRCVATFRVHDEGVW 347

 Score = 29.3 bits (64), Expect = 7.9,   Method: Compositional matrix adjust.
 Identities = 28/128 (21%), Positives = 48/128 (37%), Gaps = 1/128 (0%)
 Frame = -3

Query: 88  TLERVHMFEAHSDYIRCIAVHPTQPFILTSSDDMLIKLWDWDKKWSCSQVFEGHTHYVMQ 147
           T  ++   + H+D ++ + ++      L+ S D  I+LW   ++  C   F  H   V  
Sbjct: 520 TCHKLMKLKGHTDNVKALVLNRDGTQCLSGSSDGTIRLWSLGQQ-RCVATFRVHDEGVWA 344

Query: 148 IVINPKDNNQFASASLDRTIKVWQLGSSSP-NFTLEGHEKGVNCIDYYSGGDKPYLISGA 206
           +  N      ++     R  +VW     +P N  L   EK        +  D P L    
Sbjct: 343 LQANESFTTLYSGG---RDHQVWATDIKNPDNRELICEEKAPVLKLELTPTDPPSLWVAT 173

Query: 207 DDRLVKIW 214
            D  +K W
Sbjct: 172 TDSCIKNW 149
>33180
          Length = 460

 Score = 36.2 bits (82), Expect = 0.053,   Method: Composition-based stats.
 Identities = 17/75 (22%), Positives = 39/75 (52%), Gaps = 1/75 (1%)
 Frame = -2

Query: 198 DKPYLISGADDRLVKIWDYQNKTCVQTLEGHAQNVSCASFHPELP-IIITGSEDGTVRIW 256
           D   ++ GA+D  + ++D ++      ++ H  +V+  +F  +   I+ +G +DG  ++W
Sbjct: 420 DNTEIVGGANDGCLYVYDRESNQRTLKIDAHDDDVNAVAFADDSSQILYSGGDDGLCKVW 241

Query: 257 HSSTYRLESTLNYGM 271
              T R ++ L  G+
Sbjct: 240 DRRTLREDNPLPVGI 196
>16199
          Length = 694

 Score = 35.4 bits (80), Expect = 0.096,   Method: Composition-based stats.
 Identities = 12/25 (48%), Positives = 18/25 (72%)
 Frame = +2

Query: 232 VSCASFHPELPIIITGSEDGTVRIW 256
           ++CA FHP+  I  TG+ED  ++IW
Sbjct: 80  LTCAQFHPDGLIFATGTEDSVIKIW 154

 Score = 32.7 bits (73), Expect = 0.73,   Method: Composition-based stats.
 Identities = 12/34 (35%), Positives = 20/34 (58%)
 Frame = +2

Query: 204 SGADDRLVKIWDYQNKTCVQTLEGHAQNVSCASF 237
           +G +D ++KIWD + +  V   +GH   V+  SF
Sbjct: 122 TGTEDSVIKIWDLKERANVANFQGHQGPVTSISF 223

 Score = 32.0 bits (71), Expect = 1.1,   Method: Composition-based stats.
 Identities = 28/129 (21%), Positives = 55/129 (42%), Gaps = 1/129 (0%)
 Frame = +1

Query: 71  WVVTGADDMQIRVFNYNTLERVHMFEAHSDY-IRCIAVHPTQPFILTSSDDMLIKLWDWD 129
           ++ T A+D  +++++   L+     +    Y ++ +    +  ++  +  D+ + L    
Sbjct: 238 YLATSAEDSVVKLWDLRKLKNFKTLQLGDKYEVKALCFDQSGTYLAVAGSDVRVYLC--- 408

Query: 130 KKWSCSQVFEGHTHYVMQIVINPKDNNQFASASLDRTIKVWQLGSSSPNFTLEGHEKGVN 189
           K+W+   VF  HT     +     + N  ASAS+DR++K          F L    + V 
Sbjct: 409 KQWNELAVFNDHTATATGVRFG-TNANFIASASMDRSLKF---------FGLN*TRQTVP 558

Query: 190 CIDYYSGGD 198
           C  Y   GD
Sbjct: 559 CCVYMCWGD 585

 Score = 31.6 bits (70), Expect = 1.7,   Method: Composition-based stats.
 Identities = 15/53 (28%), Positives = 26/53 (49%)
 Frame = +2

Query: 102 IRCIAVHPTQPFILTSSDDMLIKLWDWDKKWSCSQVFEGHTHYVMQIVINPKD 154
           + C   HP      T ++D +IK+WD  ++ + +  F+GH   V  I  +  D
Sbjct: 80  LTCAQFHPDGLIFATGTEDSVIKIWDLKERANVAN-FQGHQGPVTSISFSETD 235
>04358
          Length = 2430

 Score = 35.4 bits (80), Expect = 0.099,   Method: Compositional matrix adjust.
 Identities = 19/64 (29%), Positives = 33/64 (51%), Gaps = 1/64 (1%)
 Frame = +1

Query: 194  YSGGDKPYLISGADDRLVKIWDYQNKTCVQTLEGHAQNVSCASF-HPELPIIITGSEDGT 252
            ++GG    + + + + +V+++         TL GH   +S   F H +  +I+T S D T
Sbjct: 1315 HTGGADSLVAAASSNFMVRLYSRCRLAQTNTLTGHDDVISSIRFLHTDPGLIMTASHDHT 1494

Query: 253  VRIW 256
            VRIW
Sbjct: 1495 VRIW 1506

 Score = 35.4 bits (80), Expect = 0.11,   Method: Compositional matrix adjust.
 Identities = 21/82 (25%), Positives = 38/82 (46%), Gaps = 4/82 (4%)
 Frame = +1

Query: 188  VNCIDYYSGGDKPYLISG---ADDRLVKIWDYQNKTCVQTLEG-HAQNVSCASFHPELPI 243
            V+CI        P L++G    D  ++ + D +    V++L G H   V C  +  +   
Sbjct: 2011 VDCIPANQSTSPPCLVAGTHTGDLHVLDLSDLEEVKVVRSLSGGHTDTVRCLHWDKQTQT 2190

Query: 244  IITGSEDGTVRIWHSSTYRLES 265
            ++TG ED  + +W S    ++S
Sbjct: 2191 LVTGGEDSMLCLWSSDASGIQS 2256

 Score = 29.6 bits (65), Expect = 5.3,   Method: Compositional matrix adjust.
 Identities = 44/208 (21%), Positives = 79/208 (37%), Gaps = 23/208 (11%)
 Frame = +1

Query: 92   VHMFEAHSDYIRCIAVHPT---QPFILTSSDDMLIKLWDWDKKWSCSQVFEGHTHYVMQI 148
            V +++    Y+  +A   T      +  +S + +++L+    + + +    GH   +  I
Sbjct: 1264 VSLYKTEPHYVLGLAAQHTGGADSLVAAASSNFMVRLYS-RCRLAQTNTLTGHDDVISSI 1440

Query: 149  VINPKDNNQFASASLDRTIKVWQ-LGSSSPNFTLEGHEKGVNC--IDYYSGGDKPYLISG 205
                 D     +AS D T+++W    S S        E+   C  +          L +G
Sbjct: 1441 RFLHTDPGLIMTASHDHTVRIWDPRASVSKEVQRFSGEQNTKCSVLSCDVNISDRVLCAG 1620

Query: 206  A----DDRLVKIWDYQNKTCVQTLE-GHAQNVSCASFHPEL-PIIITGSEDGTVRIWH-- 257
                 DD  +  WD +    +   E  H  +++   F P     ++TGS DG V ++   
Sbjct: 1621 TEMSNDDAYLLFWDRRKDKLLGCYEDSHHDDITQVHFGPTSEKTLLTGSTDGLVNVFDVM 1800

Query: 258  --------SSTYRLESTLNYGMERV-WC 276
                     STY  E+T+    ER  WC
Sbjct: 1801 QTTEDDALMSTYNTEATV----ERAGWC 1872
>17298
          Length = 476

 Score = 35.4 bits (80), Expect = 0.10,   Method: Composition-based stats.
 Identities = 14/33 (42%), Positives = 21/33 (63%)
 Frame = -1

Query: 228 HAQNVSCASFHPELPIIITGSEDGTVRIWHSST 260
           HA  V+C  F+ E  +I++GS D TVR W + +
Sbjct: 215 HAGTVNCVKFNEESTVILSGSLDNTVRAWDTRS 117
>15745
          Length = 1183

 Score = 35.4 bits (80), Expect = 0.11,   Method: Compositional matrix adjust.
 Identities = 38/136 (27%), Positives = 61/136 (44%), Gaps = 9/136 (6%)
 Frame = +2

Query: 92  VHMFEAHSDYIRCIAVHPT--QPFILTSSDDMLIKLWDWDKKWSCSQ-----VFEGHTHY 144
            H+  +  D ++ I  HPT     +L   +D +I +WD +   S +Q       EG    
Sbjct: 410 CHLHSSDHD-VKGILWHPTGDSQTVLGVCEDRVI-MWDLNVASSSAQQTDMITLEGKGQP 583

Query: 145 VMQI-VINPKDNNQFASASLDRTIKVWQLGSSSPNFTLEG-HEKGVNCIDYYSGGDKPYL 202
            +     NP  N    + + + TI+ W L S    + +EG H + V  +D ++   + YL
Sbjct: 584 RLTCGRWNPHHNCAQIATANEATIRGWDLRSKQQTYQMEGAHGQLVRDLD-FNPNRQYYL 760

Query: 203 ISGADDRLVKIWDYQN 218
            S  DD  VK WD +N
Sbjct: 761 ASCGDDCRVKFWDTRN 808

 Score = 32.7 bits (73), Expect = 0.75,   Method: Compositional matrix adjust.
 Identities = 21/78 (26%), Positives = 40/78 (51%), Gaps = 5/78 (6%)
 Frame = +2

Query: 73  VTGADDMQIRVFNYNTLERVHMFE-AHSDYIRCIAVHPTQPFILTS-SDDMLIKLWDWDK 130
           +  A++  IR ++  + ++ +  E AH   +R +  +P + + L S  DD  +K WD   
Sbjct: 629 IATANEATIRGWDLRSKQQTYQMEGAHGQLVRDLDFNPNRQYYLASCGDDCRVKFWD--- 799

Query: 131 KWSCSQ---VFEGHTHYV 145
             +CS+   V   H+H+V
Sbjct: 800 TRNCSEPLKVLSDHSHWV 853
>15972
          Length = 1069

 Score = 35.0 bits (79), Expect = 0.13,   Method: Compositional matrix adjust.
 Identities = 13/33 (39%), Positives = 19/33 (57%)
 Frame = +3

Query: 95  FEAHSDYIRCIAVHPTQPFILTSSDDMLIKLWD 127
           F  H   +R +AVHP+    LT S D  ++LW+
Sbjct: 225 FSGHKGPVRHLAVHPSGKLTLTVSQDRTLRLWN 323

 Score = 30.8 bits (68), Expect = 2.7,   Method: Compositional matrix adjust.
 Identities = 13/41 (31%), Positives = 23/41 (56%)
 Frame = +3

Query: 223 QTLEGHAQNVSCASFHPELPIIITGSEDGTVRIWHSSTYRL 263
           +T  GH   V   + HP   + +T S+D T+R+W++   R+
Sbjct: 219 RTFSGHKGPVRHLAVHPSGKLTLTVSQDRTLRLWNNMNGRI 341
>31054
          Length = 392

 Score = 35.0 bits (79), Expect = 0.14,   Method: Compositional matrix adjust.
 Identities = 30/123 (24%), Positives = 48/123 (39%), Gaps = 8/123 (6%)
 Frame = -2

Query: 152 PKDNNQFASASLDRTIKVWQLGSSSPNFTLEGHEKGVNCIDYYSGGDKPYLISGADDRLV 211
           P     FA  S D  +K W+    +    L GH   +N +   S G    L+SGAD+  +
Sbjct: 385 PSKAVHFAXGSPD-XVKQWKFPDGNFIQNLSGHNAIINTLAVNSDG---VLVSGADNGTM 218

Query: 212 KIWDYQNKTCVQTLEGHAQNVS--------CASFHPELPIIITGSEDGTVRIWHSSTYRL 263
            +WD++     Q +    Q  S          +F      +IT   D T++++       
Sbjct: 217 HLWDWRTGYNFQRIHAAVQPGSLDSESGFFACTFDQSESRLITAEADKTIKVYREDDTAT 38

Query: 264 EST 266
           E T
Sbjct: 37  EET 29
>05393
          Length = 904

 Score = 35.0 bits (79), Expect = 0.15,   Method: Compositional matrix adjust.
 Identities = 27/107 (25%), Positives = 55/107 (51%), Gaps = 5/107 (4%)
 Frame = +1

Query: 155 NNQFASASLDRTIKVWQLGSSSP---NFTLEGH-EKGVNCIDYYSGGDKPYLISGADDRL 210
           +    + S D T+KV    S+     ++T+EG  EK V     ++  +   L++  D  +
Sbjct: 1   SRHLLTGSFDNTVKVVDCRSAETCHKSWTVEGEVEKAV-----WNHHNPLQLLACTDKGM 165

Query: 211 VKIWDYQNKTCVQTLEGHAQNVSCASFHPELP-IIITGSEDGTVRIW 256
           V  +D +++  V ++  H+  V+      ++P ++IT SED T+++W
Sbjct: 166 VYCFDIRHEKPVFSVGAHSSCVTGVCLSSQIPGLMITTSEDKTMKVW 306

 Score = 31.6 bits (70), Expect = 1.7,   Method: Compositional matrix adjust.
 Identities = 31/158 (19%), Positives = 67/158 (42%), Gaps = 6/158 (3%)
 Frame = +1

Query: 72  VVTGADDMQIRVFNYNTLERVHM-FEAHSDYIRCIAVHPTQPFILTSSDDMLIKLWDWDK 130
           ++TG+ D  ++V +  + E  H  +    +  + +  H     +L  +D  ++  +D   
Sbjct: 10  LLTGSFDNTVKVVDCRSAETCHKSWTVEGEVEKAVWNHHNPLQLLACTDKGMVYCFDIRH 189

Query: 131 KWSCSQVFE--GHTHYVMQIVINPKDNNQFASASLDRTIKVWQLGSSSPN--FTLEGHEK 186
           +     VF    H+  V  + ++ +      + S D+T+KVW +    P   F+     K
Sbjct: 190 E---KPVFSVGAHSSCVTGVCLSSQIPGLMITTSEDKTMKVWDIQDDKPTHVFSRNLKMK 360

Query: 187 GVNCIDYYSGGDKPYLIS-GADDRLVKIWDYQNKTCVQ 223
            ++C       + P++ + G   R  K+WD +    V+
Sbjct: 361 ELHCTGCCP--EAPFVFAVGGGRREPKVWDIRESAAVR 468
>10264
          Length = 416

 Score = 34.7 bits (78), Expect = 0.19,   Method: Composition-based stats.
 Identities = 22/80 (27%), Positives = 35/80 (43%), Gaps = 1/80 (1%)
 Frame = -1

Query: 181 LEGHEKGVNCIDYYSGGDKPYLISGADDRLVKIWDYQNKTCVQTLEGHAQNVSCASFHPE 240
           L GH + V  + +    D   L+S   D    +WD Q  T +   +GH   +    F   
Sbjct: 257 LSGHSQRVTDMSWSPHHDA-RLVSVGYDAEAFVWDVQKGTALAQFKGHMGRLLTCQFSGL 81

Query: 241 LP-IIITGSEDGTVRIWHSS 259
            P +++TG  D +V +W  S
Sbjct: 80  DPDLVMTGGSDASVHVWRVS 21

 Score = 29.6 bits (65), Expect = 5.0,   Method: Composition-based stats.
 Identities = 18/78 (23%), Positives = 33/78 (42%), Gaps = 1/78 (1%)
 Frame = -1

Query: 138 FEGHTHYVMQIVINPKDNNQFASASLDRTIKVWQLGSSSPNFTLEGHE-KGVNCIDYYSG 196
             GH+  V  +  +P  + +  S   D    VW +   +     +GH  + + C   +SG
Sbjct: 257 LSGHSQRVTDMSWSPHHDARLVSVGYDAEAFVWDVQKGTALAQFKGHMGRLLTC--QFSG 84

Query: 197 GDKPYLISGADDRLVKIW 214
            D   +++G  D  V +W
Sbjct: 83  LDPDLVMTGGSDASVHVW 30
>01598
          Length = 1545

 Score = 34.7 bits (78), Expect = 0.19,   Method: Compositional matrix adjust.
 Identities = 22/80 (27%), Positives = 35/80 (43%), Gaps = 1/80 (1%)
 Frame = +1

Query: 181  LEGHEKGVNCIDYYSGGDKPYLISGADDRLVKIWDYQNKTCVQTLEGHAQNVSCASFHPE 240
            L GH + V  + +    D   L+S   D    +WD Q  T +   +GH   +    F   
Sbjct: 1288 LSGHSQRVTDMSWSPHHDA-RLVSVGYDAEAFVWDVQKGTALAQFKGHMGRLLTCQFSGL 1464

Query: 241  LP-IIITGSEDGTVRIWHSS 259
             P +++TG  D +V +W  S
Sbjct: 1465 DPDLVMTGGSDASVHVWRVS 1524

 Score = 31.6 bits (70), Expect = 1.4,   Method: Compositional matrix adjust.
 Identities = 35/171 (20%), Positives = 63/171 (36%), Gaps = 25/171 (14%)
 Frame = +1

Query: 69   KNWVVTGADDMQIRVFNYNTLERVHMFEAHSDYIRCIAVHP----TQP-------FILTS 117
            +N    G D+  + V     L+ V         I C+  HP      P       ++  +
Sbjct: 1009 QNAAAVGTDEGSVYVVTIQDLKIVAAIRTQQKLINCVRWHPRLTDQSPAGSPCCHWLAAA 1188

Query: 118  SDDMLIKLWDW---------DKKWS----CSQVFEGHTHYVMQIVINPKDNNQFASASLD 164
             +D +I + D          DK+ S      +   GH+  V  +  +P  + +  S   D
Sbjct: 1189 GNDQVIHVVDLASVFAEREGDKETSLILTSLRELSGHSQRVTDMSWSPHHDARLVSVGYD 1368

Query: 165  RTIKVWQLGSSSPNFTLEGH-EKGVNCIDYYSGGDKPYLISGADDRLVKIW 214
                VW +   +     +GH  + + C   +SG D   +++G  D  V +W
Sbjct: 1369 AEAFVWDVQKGTALAQFKGHMGRLLTC--QFSGLDPDLVMTGGSDASVHVW 1515

 Score = 28.9 bits (63), Expect = 8.9,   Method: Compositional matrix adjust.
 Identities = 42/195 (21%), Positives = 71/195 (36%), Gaps = 25/195 (12%)
 Frame = +1

Query: 72  VVTGADDMQIRVFNY----NTLERVHMFEAHSDYIRCIAVHPTQPFILT-SSDDMLIKLW 126
           V  G  D  IR +N     N  +   +++     +  +A HPT+   L   +DD  I ++
Sbjct: 553 VAVGVGDSMIRTWNMSNKTNPYDVTTLWQGIKSKVTAVAWHPTKEGWLGFGTDDGRIGVF 732

Query: 127 DW--DKKWSCSQVFEGHTHYVM---QIVINPKDNNQFASAS------LDRTIKVWQLGSS 175
           D    K  + S  F   T YV+      ++P D   F+  S      L+ +  V   G  
Sbjct: 733 DVLSHKMPTLSNTFHHRTAYVVCWGPASLSPTDGKSFSLYSVGDCKILEHSSAVLSRGEK 912

Query: 176 SPNF---------TLEGHEKGVNCIDYYSGGDKPYLISGADDRLVKIWDYQNKTCVQTLE 226
             N                KG+   +     D+     G D+  V +   Q+   V  + 
Sbjct: 913 KANAIDITQKIGAVNSDQVKGLKATELSWSPDQNAAAVGTDEGSVYVVTIQDLKIVAAIR 1092

Query: 227 GHAQNVSCASFHPEL 241
              + ++C  +HP L
Sbjct: 1093TQQKLINCVRWHPRL 1137
>15118
          Length = 1074

 Score = 34.3 bits (77), Expect = 0.21,   Method: Compositional matrix adjust.
 Identities = 30/105 (28%), Positives = 44/105 (41%), Gaps = 3/105 (2%)
 Frame = +3

Query: 155 NNQFASASLDRTIKVWQLGSSSPNFTLEGHEK---GVNCIDYYSGGDKPYLISGADDRLV 211
           N    +A  D  IK W+ GS      L    K   G++ I  +   D   L    +D  V
Sbjct: 228 NCLLITAGGDCDIKFWRFGSRDRARVLLKELKMSEGISRILLHR--DSNMLAVVLEDFTV 401

Query: 212 KIWDYQNKTCVQTLEGHAQNVSCASFHPELPIIITGSEDGTVRIW 256
            + D      V+   GH+ +++  SF  +   +IT S D TVR W
Sbjct: 402 SVIDVDTLRVVRVFSGHSNSITDLSFSGDGRWLITASMDCTVRTW 536
>12140
          Length = 727

 Score = 33.9 bits (76), Expect = 0.29,   Method: Composition-based stats.
 Identities = 31/86 (36%), Positives = 40/86 (46%), Gaps = 9/86 (10%)
 Frame = +2

Query: 202 LISGADDRLVKIWDYQNKTCV--QTLEGHAQNVSCASFHPE--LP--IIITGSEDGTVRI 255
            +SG  D LVKIW       V  Q LEGH+  V   ++ P   LP  +I + S+D  V I
Sbjct: 269 FVSGGCDNLVKIWREDETGWVEDQKLEGHSDWVRDVAWAPSIGLPRNVIASCSQDCRVII 448

Query: 256 WH---SSTYRLESTLNYGMERVWCVA 278
           W    SS       LN   + VW V+
Sbjct: 449 WTNDGSSNQWTSRILNKFSDVVWHVS 526
>12841
          Length = 1364

 Score = 33.5 bits (75), Expect = 0.39,   Method: Compositional matrix adjust.
 Identities = 25/96 (26%), Positives = 41/96 (42%), Gaps = 6/96 (6%)
 Frame = +1

Query: 131  KWSCS------QVFEGHTHYVMQIVINPKDNNQFASASLDRTIKVWQLGSSSPNFTLEGH 184
            K SCS      + + GHT  V  I  +P  ++ F S S D +I++W    ++P  T    
Sbjct: 997  KCSCSYNEQYLETYSGHTAPVYHIRWSPFVSDIFLSCSADWSIRLWHQDRTTPILTFHSS 1176

Query: 185  EKGVNCIDYYSGGDKPYLISGADDRLVKIWDYQNKT 220
             K V+  D         + +   +  V++WD    T
Sbjct: 1177 TKTVH--DVCWSPRSSTVFACVHEGAVEVWDLAQST 1278

 Score = 28.9 bits (63), Expect = 8.5,   Method: Compositional matrix adjust.
 Identities = 20/75 (26%), Positives = 35/75 (46%), Gaps = 1/75 (1%)
 Frame = +1

Query: 184 HEKGVNCIDYYSGGDKPYLISGADDRLVKIWDYQNKTCVQTLEGHAQNVSCASFHPELP- 242
           H  G+ C D++S     YL    +  + K     N+  ++T  GH   V    + P +  
Sbjct: 916 HAGGL-CFDFHSRDLNVYLAGTEEGYIHKCSCSYNEQYLETYSGHTAPVYHIRWSPFVSD 1092

Query: 243 IIITGSEDGTVRIWH 257
           I ++ S D ++R+WH
Sbjct: 1093IFLSCSADWSIRLWH 1137
>29912
          Length = 510

 Score = 33.5 bits (75), Expect = 0.42,   Method: Composition-based stats.
 Identities = 26/108 (24%), Positives = 46/108 (42%), Gaps = 4/108 (3%)
 Frame = +3

Query: 153 KDNNQFASASLDRTIKVWQLGSSSPNFTLEGHEKGVNCIDY----YSGGDKPYLISGADD 208
           K+ N  A  +    ++VW +       T+ GH   V  + +     S G +   I   D 
Sbjct: 39  KEGNYLALGTSTGEVQVWDVTQQKKLRTMAGHAARVGSLSWNSFIVSSGSRSGNIHHHD- 215

Query: 209 RLVKIWDYQNKTCVQTLEGHAQNVSCASFHPELPIIITGSEDGTVRIW 256
             V++ D+     V TL GH+Q V    + P+   + +G+ D  + +W
Sbjct: 216 --VRVADHH----VGTLSGHSQEVCGLRWSPDGKYLASGANDNLLCVW 341

 Score = 31.2 bits (69), Expect = 2.0,   Method: Composition-based stats.
 Identities = 19/71 (26%), Positives = 35/71 (49%)
 Frame = +3

Query: 183 GHEKGVNCIDYYSGGDKPYLISGADDRLVKIWDYQNKTCVQTLEGHAQNVSCASFHPELP 242
           G E+ +  + +   G+  YL  G     V++WD   +  ++T+ GHA  V   S++    
Sbjct: 3   GPEEYIGAVSWIKEGN--YLALGTSTGEVQVWDVTQQKKLRTMAGHAARVGSLSWNSF-- 170

Query: 243 IIITGSEDGTV 253
           I+ +GS  G +
Sbjct: 171 IVSSGSRSGNI 203
>21763
          Length = 923

 Score = 33.5 bits (75), Expect = 0.43,   Method: Compositional matrix adjust.
 Identities = 23/107 (21%), Positives = 45/107 (42%), Gaps = 10/107 (9%)
 Frame = +1

Query: 165 RTIKVWQLGSSSPNFTLEGHEKGVNCIDYYSGGDKPYLISGADDRLVKIWDYQNKTC--- 221
           R ++++ L +      L+ + K ++ +D + GGD            V I  Y  K+C   
Sbjct: 382 RFVRIYNLLTQQFVKKLQTNCKWISSMDVHPGGDN-----------VIIGSYDCKSCWFD 528

Query: 222 -------VQTLEGHAQNVSCASFHPELPIIITGSEDGTVRIWHSSTY 261
                   + L  H + V   S+H   P+  + S+DG++ + H   +
Sbjct: 529 LDLSTKPYKILRHHKRAVRHVSYHHRYPLFASASDDGSIIVCHGKVF 669
>25526
          Length = 443

 Score = 33.1 bits (74), Expect = 0.51,   Method: Compositional matrix adjust.
 Identities = 15/37 (40%), Positives = 22/37 (59%)
 Frame = +2

Query: 73  VTGADDMQIRVFNYNTLERVHMFEAHSDYIRCIAVHP 109
           V G D   +RVFNYNT+E V M +++   + C+   P
Sbjct: 335 VVGQDGF-LRVFNYNTMELVGMMKSYFGGLLCVCWSP 442
>30297
          Length = 822

 Score = 33.1 bits (74), Expect = 0.58,   Method: Compositional matrix adjust.
 Identities = 14/54 (25%), Positives = 30/54 (55%)
 Frame = -1

Query: 222 VQTLEGHAQNVSCASFHPELPIIITGSEDGTVRIWHSSTYRLESTLNYGMERVW 275
           +Q+  GH ++VSC     +  +++T + D TVR+W +  + + +   +G   +W
Sbjct: 249 IQSWRGHVESVSCLDLVEQNKVLLTSAADCTVRMWTTDGHYIGT---FGQPELW 97
>07151
          Length = 512

 Score = 32.7 bits (73), Expect = 0.59,   Method: Compositional matrix adjust.
 Identities = 15/44 (34%), Positives = 26/44 (59%), Gaps = 1/44 (2%)
 Frame = -1

Query: 186 KGVNCIDYYSGGDKPYLISGADDRLVKIWD-YQNKTCVQTLEGH 228
           KGV C D+    DK  +++G  DR++++W+ Y ++     L GH
Sbjct: 161 KGVKCFDFSK--DKNIIVTGGMDRIIRLWNPYVSQKPTAMLRGH 36
>34005
          Length = 456

 Score = 32.7 bits (73), Expect = 0.73,   Method: Composition-based stats.
 Identities = 21/84 (25%), Positives = 36/84 (42%), Gaps = 4/84 (4%)
 Frame = +1

Query: 154 DNNQFASASLDRTIKVWQ--LGSSSPNF-TLEGHEKGVNCIDYYSGGDKPYLISGA-DDR 209
           D    AS S D ++ +W   LG   P   TL  H+  V  + +     +     G  +DR
Sbjct: 145 DATFLASGSNDNSVNIWDSTLGMDVPPLHTLTSHQAAVKAVAWCPWQTRMLATGGGTNDR 324

Query: 210 LVKIWDYQNKTCVQTLEGHAQNVS 233
            ++ W+     CV+ ++  +Q  S
Sbjct: 325 HIRFWNTNTGACVKAVDTQSQVCS 396
>25400
          Length = 462

 Score = 32.3 bits (72), Expect = 0.78,   Method: Composition-based stats.
 Identities = 21/62 (33%), Positives = 29/62 (46%), Gaps = 1/62 (1%)
 Frame = +3

Query: 201 YLISGADDRLVKIWDYQNKTCVQTLEG-HAQNVSCASFHPELPIIITGSEDGTVRIWHSS 259
           Y+ SG     + I+D      V+ L+G H   V   S+HP    +I+ S DGTV  W   
Sbjct: 3   YVYSGCATGTILIYDLLTGRVVRKLDGGHRSCVRDVSWHPYTNTLISSSWDGTVGKWDYF 182

Query: 260 TY 261
            Y
Sbjct: 183 DY 188
>25470
          Length = 400

 Score = 32.3 bits (72), Expect = 0.87,   Method: Composition-based stats.
 Identities = 22/60 (36%), Positives = 32/60 (53%), Gaps = 6/60 (10%)
 Frame = -3

Query: 692 HAQDYGGLLLL--ATASGNASMVNKL----AEGAERDGKNNVAFMSYFLQGKLDACLELL 745
           HA+D GGL+ L  A + G+A +V  L    A+   RD  N        ++GK+D C+ LL
Sbjct: 317 HARDDGGLIPLHNACSFGHAEVVQLLLRHGADPNARDNWNYTPLHEAAIKGKIDVCIVLL 138
>04395
          Length = 1145

 Score = 32.0 bits (71), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 16/44 (36%), Positives = 25/44 (56%), Gaps = 2/44 (4%)
 Frame = +3

Query: 234 CASFHP-ELPIIITGSEDGTVRIWHSSTYRLE-STLNYGMERVW 275
           C   HP +L I+ TGS+DGT+ +W    +R   +TL+     +W
Sbjct: 489 CVDKHPGQLHIVATGSQDGTLTVWDLRHHRFPMTTLDAHHSSMW 620
>27475
          Length = 369

 Score = 31.6 bits (70), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 23/85 (27%), Positives = 38/85 (44%), Gaps = 3/85 (3%)
 Frame = +2

Query: 137 VFEGHTHYVMQIVINPKDNNQFASASLDRTIKVWQLGSSSPNFTL---EGHEKGVNCIDY 193
            F  HT +V  +  +P   + F S S D  +K+W   + SP  TL     HE  +  +D+
Sbjct: 53  AFTSHTGWVTGVDWSPTREHLFLSGSYDNVLKLWD--TRSPKATLYDMNWHEDRILAVDW 226

Query: 194 YSGGDKPYLISGADDRLVKIWDYQN 218
                   L+SG  D  + ++ Y +
Sbjct: 227 ---SIPELLLSGGVDNKLHVFSYSS 292
>14500
          Length = 1238

 Score = 31.2 bits (69), Expect = 1.7,   Method: Compositional matrix adjust.
 Identities = 23/95 (24%), Positives = 43/95 (45%), Gaps = 2/95 (2%)
 Frame = +3

Query: 164 DRTIKVWQLGSSSPNFTLEGHEKGVNCIDYYSGGDKPYLISG--ADDRLVKIWDYQNKTC 221
           DR I  W   + +   +++   K   C   +S   +  + S   A ++L+ IW Y   + 
Sbjct: 273 DRHIHFWNCNTGTNLSSVD--TKSQVCALLWSKEHRELISSHGFAQNQLI-IWKYPAMSR 443

Query: 222 VQTLEGHAQNVSCASFHPELPIIITGSEDGTVRIW 256
           V  L GH   V   +  P+   +++ + D T+R+W
Sbjct: 444 VAELTGHTARVLHMAMSPDGETVVSAAADETLRLW 548
>30295
          Length = 593

 Score = 31.2 bits (69), Expect = 1.8,   Method: Composition-based stats.
 Identities = 32/135 (23%), Positives = 54/135 (40%), Gaps = 11/135 (8%)
 Frame = +2

Query: 4   RLDIKRKLTARSDRVKSVDLHPTEPW------MLASLYNGSVCVWNHETQTLVKTFEVCD 57
           R+ ++ + T R    K   +H    W      ++++  +G + VW+  T   V    +  
Sbjct: 206 RIQMRTRRTLRXHLAKIYAMH----WATDSRNLVSASQDGKLIVWDGYTTNKVHAIPLRS 373

Query: 58  LPVRAAKFVARKNWVVTGADDMQIRVFNYNTLE---RVHM-FEAHSDYIRCIA-VHPTQP 112
             V    +     +V  G  D    +++  T E   RV      H+ Y+ C   +   Q 
Sbjct: 374 SWVMTCAYAPSGGYVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFIDDNQ- 550

Query: 113 FILTSSDDMLIKLWD 127
            I+TSS DM   LWD
Sbjct: 551 -IVTSSGDMTCALWD 592
>04088
          Length = 511

 Score = 31.2 bits (69), Expect = 2.0,   Method: Compositional matrix adjust.
 Identities = 26/100 (26%), Positives = 41/100 (41%), Gaps = 1/100 (1%)
 Frame = +3

Query: 161 ASLDRTIKVWQLGSSSPNFTLEGHEKGVNCIDYYSGGDKPYLISGADDRLVKIWDYQNKT 220
           +S D T+++    +        GH+     ID     +   ++SG++D  V  WD     
Sbjct: 84  SSQDNTVRLMDKDTGEMLNEFTGHKHSQYKIDSCLNNEDTLVVSGSEDGKVYFWDLVEAK 263

Query: 221 CVQTLEGHAQN-VSCASFHPELPIIITGSEDGTVRIWHSS 259
            V TL+      V   SFH     ++T   D  V +W SS
Sbjct: 264 LVDTLDHKTTRPVHSLSFHHAELCLMTACADK-VFLWRSS 380

 Score = 29.6 bits (65), Expect = 5.6,   Method: Compositional matrix adjust.
 Identities = 24/92 (26%), Positives = 41/92 (44%), Gaps = 4/92 (4%)
 Frame = +3

Query: 186 KGVNCIDYYSGGDKPYLISGADDRLVKIWDYQNKTCVQTLEGHAQNV----SCASFHPEL 241
           K V  + +   G +  L+S  D+  V++ D      +    GH  +     SC   + E 
Sbjct: 33  KAVTSVTFTRDG-QCSLVSSQDNT-VRLMDKDTGEMLNEFTGHKHSQYKIDSC--LNNED 200

Query: 242 PIIITGSEDGTVRIWHSSTYRLESTLNYGMER 273
            ++++GSEDG V  W     +L  TL++   R
Sbjct: 201 TLVVSGSEDGKVYFWDLVEAKLVDTLDHKTTR 296
>31118
          Length = 390

 Score = 30.8 bits (68), Expect = 2.4,   Method: Composition-based stats.
 Identities = 15/30 (50%), Positives = 18/30 (60%)
 Frame = -2

Query: 98  HSDYIRCIAVHPTQPFILTSSDDMLIKLWD 127
           HS  IRCI   P+  ++LT S D  IKL D
Sbjct: 383 HSAEIRCIRFSPSAYYMLTCSYDSTIKLTD 294
>05303
          Length = 782

 Score = 30.8 bits (68), Expect = 2.5,   Method: Compositional matrix adjust.
 Identities = 18/74 (24%), Positives = 31/74 (41%), Gaps = 12/74 (16%)
 Frame = -3

Query: 198 DKPYLISGADDRLVKIWDYQNKT-----------CVQTLEGHAQN-VSCASFHPELPIII 245
           ++ Y I G  D  V +W+   K            C Q      +N ++  +      ++ 
Sbjct: 669 NESYFIMGGQDNSVSLWNVNKKKALVCVTSAHSGCSQIEGSKGENWITAVASLQFTDLVA 490

Query: 246 TGSEDGTVRIWHSS 259
           TGS+DG +R+W  S
Sbjct: 489 TGSKDGCIRLWQCS 448
>06253
          Length = 1049

 Score = 30.8 bits (68), Expect = 2.9,   Method: Compositional matrix adjust.
 Identities = 22/60 (36%), Positives = 31/60 (51%), Gaps = 6/60 (10%)
 Frame = -1

Query: 692 HAQDYGGLLLLATAS--GNASMVNKL----AEGAERDGKNNVAFMSYFLQGKLDACLELL 745
           HA+D GGL+ L  A   G+A +V  L    A+   RD  N        ++GK+D C+ LL
Sbjct: 965 HARDDGGLIPLHNACSFGHAEVVQLLLRHGADPNARDNWNYTPLHEAAIKGKIDVCIVLL 786
>25880
          Length = 423

 Score = 30.4 bits (67), Expect = 3.1,   Method: Compositional matrix adjust.
 Identities = 25/102 (24%), Positives = 52/102 (50%), Gaps = 4/102 (3%)
 Frame = +2

Query: 166 TIKVWQLGSSSPNFTLEGHEKGVNCIDYYSGGDKPYLISGADDRLVKIWDYQNKTCVQTL 225
           T KVW   S +   + + H+  V  + + +  +   +++G++++LV++++ +       L
Sbjct: 2   TGKVWNAVSGAEIHSFQ-HKHIVKSVAFDNSSEN--IVTGSNEKLVRVFNLEQPDAEPEL 172

Query: 226 -EGHAQNVSCASFHPELPIIITGSEDGTVRIWHSS---TYRL 263
             GH   +  A       +  +GSEDGT+R+W ++   TY L
Sbjct: 173 YGGHTGAIKRA-------LYASGSEDGTLRLWQTTVGKTYGL 277
>27681
          Length = 465

 Score = 30.4 bits (67), Expect = 3.8,   Method: Composition-based stats.
 Identities = 19/71 (26%), Positives = 34/71 (47%), Gaps = 14/71 (19%)
 Frame = +2

Query: 202 LISGADDRLVKIWDYQNKT-----------CVQ---TLEGHAQNVSCASFHPELPIIITG 247
           L SG+ D   +IW+  ++T           C+Q   T     ++V+   ++ E  ++ TG
Sbjct: 38  LASGSGDSTARIWNMTSETPNNANQLVLRHCIQKGGTEVPSNKDVTSLDWNSEGTLLATG 217

Query: 248 SEDGTVRIWHS 258
           S DG  R+W +
Sbjct: 218 SYDGYARLWRT 250
>31864
          Length = 545

 Score = 30.4 bits (67), Expect = 3.8,   Method: Compositional matrix adjust.
 Identities = 12/31 (38%), Positives = 19/31 (61%)
 Frame = +2

Query: 225 LEGHAQNVSCASFHPELPIIITGSEDGTVRI 255
           L+GH   ++  +FHP+     +G EDG VR+
Sbjct: 329 LKGHFGPINSLAFHPDGKSYASGGEDGFVRV 421
>31384
          Length = 474

 Score = 30.0 bits (66), Expect = 4.0,   Method: Composition-based stats.
 Identities = 26/104 (25%), Positives = 43/104 (41%), Gaps = 13/104 (12%)
 Frame = -1

Query: 85  NYNTLERVHMFEAHSDYIRCIAVHP---TQPFILTSSDDMLIKLWDWDKKWSCSQVFEG- 140
           N N ++   +     D + C+   P      F+++ S         WD K SC +V +  
Sbjct: 318 NTNPMKDFEVTSPPDDSVSCLKFSPGALPSTFLISGS---------WDNKVSCWEVQQSG 166

Query: 141 ---------HTHYVMQIVINPKDNNQFASASLDRTIKVWQLGSS 175
                    HT  V+ +  +  D  +  +AS D+T KVW L S+
Sbjct: 165 QTIPKAQQTHTGPVLDVDWS-DDGTKVFTASCDKTAKVWDLNSN 37
>05642
          Length = 445

 Score = 29.6 bits (65), Expect = 6.0,   Method: Composition-based stats.
 Identities = 23/78 (29%), Positives = 34/78 (43%), Gaps = 1/78 (1%)
 Frame = -1

Query: 183 GHEKGVNCIDYYSGGDKPYLISGADDRLVKIWDYQNKTCVQTLEGH-AQNVSCASFHPEL 241
           GH+     ID     +   ++SG++D  V  WD      V TL+    + V   SFH   
Sbjct: 421 GHKHSQYKIDSCLNNEDTLVVSGSEDGKVYFWDLVEAKLVDTLDHKTTRPVHSLSFHHAE 242

Query: 242 PIIITGSEDGTVRIWHSS 259
             ++T   D  V +W SS
Sbjct: 241 LCLMTACAD-KVFLWRSS 191
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|46909575|ref|NP_075527.2| growth factor, erv1 (S.
cerevisiae)-like (augmenter of liver regeneration) [Mus musculus]
         (198 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

09432                                                                 199   5e-52
25334                                                                  27   4.3  
25613                                                                  27   6.9  
>09432
          Length = 1549

 Score =  199 bits (506), Expect = 5e-52,   Method: Compositional matrix adjust.
 Identities = 89/147 (60%), Positives = 115/147 (78%), Gaps = 6/147 (4%)
 Frame = +3

Query: 58  EHGKRPCRACVDFKSWMRTQ----QKRDIKFRE--DCPQDREELGRHTWAFLHTLAAYYP 111
           +   +PCRAC DF+SWM+ Q    Q + ++  +  DCP D  +LGR+TW+FLHT+AAY+P
Sbjct: 27  KKATKPCRACTDFQSWMKMQGKTAQNKQVEAEQPSDCPLDTVQLGRNTWSFLHTMAAYFP 206

Query: 112 DRPTPEQQQDMAQFIHIFSKFYPCEECAEDIRKRIGRNQPDTSTRVSFSQWLCRLHNEVN 171
           D+PT  QQ +M+QFI +FSKFYPCE CA D+R+ +  N PDTS++ + SQW CRLHN VN
Sbjct: 207 DKPTQTQQTEMSQFIRLFSKFYPCEPCAADLREDLKTNSPDTSSQHNLSQWFCRLHNRVN 386

Query: 172 RKLGKPDFDCSRVDERWRDGWKDGSCD 198
           +KLGKP+FDCS+VDERWRDGWKDGSCD
Sbjct: 387 KKLGKPEFDCSKVDERWRDGWKDGSCD 467
>25334
          Length = 1111

 Score = 27.3 bits (59), Expect = 4.3,   Method: Compositional matrix adjust.
 Identities = 17/65 (26%), Positives = 30/65 (46%), Gaps = 2/65 (3%)
 Frame = +1

Query: 131 KFYPCEECAEDIRKRIGRNQPDTSTRVSFSQWLCRLHNEV--NRKLGKPDFDCSRVDERW 188
           K +   +C    RKR G+NQ          + LC++H +V  N    +P +  S + +R 
Sbjct: 229 KIHTHSQCKSVTRKRSGKNQTP-----QMRKLLCQIHKQVWSNTNTRQPLYQYSFITQRP 393

Query: 189 RDGWK 193
            + +K
Sbjct: 394 TETFK 408
>25613
          Length = 466

 Score = 26.6 bits (57), Expect = 6.9,   Method: Compositional matrix adjust.
 Identities = 10/19 (52%), Positives = 11/19 (57%)
 Frame = -2

Query: 85  REDCPQDREELGRHTWAFL 103
           R DCP  R+EL    W FL
Sbjct: 93  RHDCPTARQELAMFHWTFL 37
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|153267502|ref|NP_619605.2| DnaJ (Hsp40) homolog,
subfamily C, member 28 isoform 2 [Mus musculus]
         (385 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

04176                                                                 200   8e-52
07620                                                                  36   0.022
02324                                                                  36   0.024
14550                                                                  32   0.29 
13998                                                                  32   0.58 
11891                                                                  27   9.9  
>04176
          Length = 2034

 Score =  200 bits (509), Expect = 8e-52,   Method: Compositional matrix adjust.
 Identities = 105/262 (40%), Positives = 169/262 (64%), Gaps = 3/262 (1%)
 Frame = +3

Query: 126 FKYNTPQHRHYLSFEGVGFGTPSQREKQYRQFRADRATEQVMEYQRQKLQREFFANSITV 185
            K+  PQHR YL FEGVGFGTPSQR++QY+Q R  R TE V +++ QKL  E   +S+ +
Sbjct: 45  IKHTAPQHRQYLEFEGVGFGTPSQRQRQYQQHRVARVTENVFQHRMQKLAAET-EDSLVI 221

Query: 186 KDVRQSKQQKITQAIERLVEDLIQESMAKGDFDNLSGKGKPLKKFSGCSYIDPMTHNLNR 245
           +D RQ+K+  I+ AIER+VEDLIQES+ +GDF+NL+G+G+PL   +   ++D  THNLN+
Sbjct: 222 QDKRQAKKTVISNAIERIVEDLIQESIKRGDFNNLAGQGRPLDHAAHNPFVDVTTHNLNK 401

Query: 246 ILIDNGYQPEWILMQKEIKDTIEQLREALLMSRKKL---GNPLSPTEQKQWAQVCEQFQE 302
           I+ +NG+ PEWI++Q EI+  + Q R++L ++ ++L       SP + K W    ++F  
Sbjct: 402 IMANNGFAPEWIMLQSEIRKELHQARQSLAVTHRRLTLVTETHSPIDSKVWRMAVDKFDR 581

Query: 303 KIRKLNKRINDFNLIVPILTRQKVHFDAQKEIIRVQEMYGAFVEANEVTEENQTDVSQGE 362
           ++ ++N +I+ FNLIVP+L +Q V +   +E+ RV++    ++  +        DVS   
Sbjct: 582 QVSEVNTKIHKFNLIVPLLDKQMVVYQTDREVRRVRDNVDDYLPQDS-DPYLLWDVSLPA 758

Query: 363 ESKTPRVKAGFLNWLNLWKSIK 384
           ++ +P      ++W  +W+ IK
Sbjct: 759 KTSSPSSLGTAVDWRQVWRDIK 824
>07620
          Length = 1775

 Score = 36.2 bits (82), Expect = 0.022,   Method: Compositional matrix adjust.
 Identities = 12/32 (37%), Positives = 24/32 (75%)
 Frame = +1

Query: 47  REYYRLLNLDEGCSVDDVRESFHKLARQYHPD 78
           ++YY +L++ + C+  D+++++ KLA Q HPD
Sbjct: 97  KDYYEVLDVKKDCTESDMKKAYRKLALQMHPD 192
>02324
          Length = 2058

 Score = 36.2 bits (82), Expect = 0.024,   Method: Compositional matrix adjust.
 Identities = 17/56 (30%), Positives = 34/56 (60%), Gaps = 2/56 (3%)
 Frame = +2

Query: 43  SQKLREYYRLLNLDEGCSVDDVRESFHKLARQYHPDSGSSDADSAT--FIKIEEAY 96
           + K+R +Y +L ++     DD+++++ KLA ++HPD      + AT  F  +++AY
Sbjct: 89  TSKIRCHYEVLGVERSADNDDLKKAYRKLALKFHPDKNPDSVEEATAQFRLVQQAY 256
>14550
          Length = 1395

 Score = 32.3 bits (72), Expect = 0.29,   Method: Compositional matrix adjust.
 Identities = 17/61 (27%), Positives = 33/61 (54%), Gaps = 1/61 (1%)
 Frame = -1

Query: 47   REYYRLLNLDEGCSVDDVRESFHKLARQYHPDSGSSDADSAT-FIKIEEAYRNVLSHAIK 105
            R++Y++L + +      ++ ++ K+A++ HPD    D ++   F  +  AY  VLS   K
Sbjct: 1137 RDFYKILGVSKSADTKQIKRAYRKIAKELHPDKNRDDPEAEQRFQDLGAAY-EVLSDEEK 961

Query: 106  R 106
            R
Sbjct: 960  R 958
>13998
          Length = 1075

 Score = 31.6 bits (70), Expect = 0.58,   Method: Compositional matrix adjust.
 Identities = 20/68 (29%), Positives = 38/68 (55%), Gaps = 6/68 (8%)
 Frame = +1

Query: 45  KLREYYRLLNLDEGCSVDDVRESFHKLARQYHPD-SGSSDAD-----SATFIKIEEAYRN 98
           K ++YY++L +    + D++++++ K A  +HPD   +S AD        F ++ EAY  
Sbjct: 196 KRKDYYKILGISRNATEDEIKKAYRKKALVHHPDRHANSSADVRKDEELKFKEVGEAY-A 372

Query: 99  VLSHAIKR 106
           +LS   K+
Sbjct: 373 ILSDGAKK 396
>11891
          Length = 937

 Score = 27.3 bits (59), Expect = 9.9,   Method: Compositional matrix adjust.
 Identities = 15/47 (31%), Positives = 25/47 (53%)
 Frame = -2

Query: 6   CMKTTRILRLHLTNASLIPPGIKMLSDPRSRMISTHESQKLREYYRL 52
           C K +R LR+HL    ++ P  + +   R  M ++HE Q + +  RL
Sbjct: 753 CFKPSRPLRVHLLFIVVLRPANRRVVLLRPLMCASHEKQVVAQASRL 613
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|13385518|ref|NP_080287.1| ADP-ribosylation
factor-like 10C [Mus musculus]
         (186 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

15973                                                                 197   1e-51
09827                                                                 119   9e-28
08153                                                                 116   5e-27
30944                                                                  93   6e-20
11378                                                                  87   4e-18
10862                                                                  87   5e-18
18208                                                                  71   2e-13
18949                                                                  67   3e-12
33605                                                                  67   5e-12
15662                                                                  57   5e-09
34468                                                                  52   1e-07
17511                                                                  50   7e-07
13901                                                                  48   2e-06
19006                                                                  48   3e-06
14456                                                                  45   2e-05
07465                                                                  45   2e-05
13750                                                                  43   8e-05
33380                                                                  41   3e-04
08428                                                                  40   4e-04
26083                                                                  40   5e-04
35581                                                                  40   5e-04
14775                                                                  39   0.001
01972                                                                  31   0.31 
00858                                                                  31   0.33 
10708                                                                  27   6.8  
>15973
          Length = 493

 Score =  197 bits (502), Expect = 1e-51,   Method: Compositional matrix adjust.
 Identities = 92/103 (89%), Positives = 101/103 (98%)
 Frame = -1

Query: 83  ERYCRGVNAIVYMIDAADREKIEASRNELHNLLDKPQLQGIPVLVLGNKRDLPNALDEKQ 142
           ERYCRGVNAIVYM+DAAD++K+EASRNELHNLLDKPQLQG+PVLVLGNKRDLP ALDEK+
Sbjct: 493 ERYCRGVNAIVYMVDAADQDKLEASRNELHNLLDKPQLQGVPVLVLGNKRDLPGALDEKE 314

Query: 143 LIEKMNLSAIQDREICCYSISCKEKDNIDITLQWLIQHSKSRR 185
           LI++MNLSAIQDREICCYSISCKEK+NIDITLQWLIQHSKS R
Sbjct: 313 LIDRMNLSAIQDREICCYSISCKEKENIDITLQWLIQHSKSGR 185
>09827
          Length = 1201

 Score =  119 bits (297), Expect = 9e-28,   Method: Compositional matrix adjust.
 Identities = 54/172 (31%), Positives = 101/172 (58%)
 Frame = -3

Query: 15   LFWKEEMELTLVGLQYSGKTTFVNVIASGQFSEDMIPTVGFNMRKVTKGNVTIKIWDIGG 74
            +F K++M + +VGL  +GKTT +  +  G+     IPT+GFN+  V   N++  +WD+GG
Sbjct: 1130 MFGKKDMRILMVGLDAAGKTTILYKLKLGEIVT-TIPTIGFNVETVEYKNISFTVWDVGG 954

Query: 75   QPRFRSMWERYCRGVNAIVYMIDAADREKIEASRNELHNLLDKPQLQGIPVLVLGNKRDL 134
            Q + R +W  Y +    +++++D+ D+E+++ +R EL  +L++ +L+   +LV  NK+DL
Sbjct: 953  QDKIRPLWRHYFQNTQGLIFVVDSNDKERVQEAREELTRMLNEDELRDAVLLVFANKQDL 774

Query: 135  PNALDEKQLIEKMNLSAIQDREICCYSISCKEKDNIDITLQWLIQHSKSRRS 186
            P+A+   ++ EK+ L  +++R     S      D +   L WL    K+ +S
Sbjct: 773  PHAMATAEITEKLGLHGLRNRTWYIQSTCATTGDGLYEGLDWLSNQLKNNKS 618
>08153
          Length = 1703

 Score =  116 bits (291), Expect = 5e-27,   Method: Compositional matrix adjust.
 Identities = 53/166 (31%), Positives = 97/166 (58%)
 Frame = +1

Query: 12  FRSLFWKEEMELTLVGLQYSGKTTFVNVIASGQFSEDMIPTVGFNMRKVTKGNVTIKIWD 71
           F++LF K+E+ + +VGL  +GKTT +  +  G+     IPT+GFN+  V   N++  +WD
Sbjct: 58  FKNLFGKKEVRILMVGLDAAGKTTILYKLKLGEIVT-TIPTIGFNVETVEYKNISFTVWD 234

Query: 72  IGGQPRFRSMWERYCRGVNAIVYMIDAADREKIEASRNELHNLLDKPQLQGIPVLVLGNK 131
           +GGQ + R +W  Y +    +++++D+ DRE+I  ++ EL  +L++  L+   +LV  NK
Sbjct: 235 VGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERINEAKEELARMLNEDDLRDAIILVFANK 414

Query: 132 RDLPNALDEKQLIEKMNLSAIQDREICCYSISCKEKDNIDITLQWL 177
           +DLPNA    ++   + L+ ++ R+    +      D +   L+WL
Sbjct: 415 QDLPNAYSASEVTAHLGLANLKGRKWYMQATCATSGDGMYEGLEWL 552
>30944
          Length = 1058

 Score = 92.8 bits (229), Expect = 6e-20,   Method: Compositional matrix adjust.
 Identities = 44/49 (89%), Positives = 47/49 (95%)
 Frame = +1

Query: 137 ALDEKQLIEKMNLSAIQDREICCYSISCKEKDNIDITLQWLIQHSKSRR 185
           ALDEK LIE+MNL+AIQDREICCYSISCKEK+NIDITLQWLIQHSKS R
Sbjct: 1   ALDEKDLIERMNLAAIQDREICCYSISCKEKENIDITLQWLIQHSKSGR 147
>11378
          Length = 1688

 Score = 87.0 bits (214), Expect = 4e-18,   Method: Compositional matrix adjust.
 Identities = 43/150 (28%), Positives = 87/150 (58%), Gaps = 5/150 (3%)
 Frame = +3

Query: 8   LLDWFRSLF-----WKEEMELTLVGLQYSGKTTFVNVIASGQFSEDMIPTVGFNMRKVTK 62
           L +WF+ +      +K+  +L  +GL  +GKTT ++++   + ++  +PT+     +++ 
Sbjct: 270 LWNWFQDMLSFLGLYKKSGKLVFLGLDNAGKTTLLHMLKDDKMAQH-VPTLHPTSEELSM 446

Query: 63  GNVTIKIWDIGGQPRFRSMWERYCRGVNAIVYMIDAADREKIEASRNELHNLLDKPQLQG 122
           G +    +D+GG  + R +W+ Y   V+ IV+++D  DRE++  ++ EL +L+   Q+  
Sbjct: 447 GGMRFTTFDLGGHRQARRVWKDYFPAVDGIVFLVDVHDRERLVEAKAELDSLMTDEQVAN 626

Query: 123 IPVLVLGNKRDLPNALDEKQLIEKMNLSAI 152
            P+LVLGNK D P A  E+++     L+++
Sbjct: 627 APILVLGNKIDKPGAASEEEIRHWFGLNSL 716
>10862
          Length = 2896

 Score = 86.7 bits (213), Expect = 5e-18,   Method: Compositional matrix adjust.
 Identities = 36/117 (30%), Positives = 68/117 (58%)
 Frame = -3

Query: 67   IKIWDIGGQPRFRSMWERYCRGVNAIVYMIDAADREKIEASRNELHNLLDKPQLQGIPVL 126
              +WD+GGQ + R +W  Y  G   +++++D ADR++I+ +R ELH +++  +++   +L
Sbjct: 2480 FNVWDVGGQDKIRPLWRHYYTGTQGLIFVVDCADRDRIDEARQELHRIINDREMRDAIIL 2301

Query: 127  VLGNKRDLPNALDEKQLIEKMNLSAIQDREICCYSISCKEKDNIDITLQWLIQHSKS 183
            +  NK+DLP+A+   ++ EK+ L+ ++DR            D +   L WL  + KS
Sbjct: 2300 IFANKQDLPDAMKPHEIQEKLGLTRLRDRNWYVQPSCATTGDGLCEGLTWLTSNHKS 2130

 Score = 40.8 bits (94), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 26/71 (36%), Positives = 40/71 (56%)
 Frame = -1

Query: 15   LFWKEEMELTLVGLQYSGKTTFVNVIASGQFSEDMIPTVGFNMRKVTKGNVTIKIWDIGG 74
            +F  +EM + ++GL  +GKTT +  +  GQ S   IPTVGFN+  V+  NV      + G
Sbjct: 2632 IFGNKEMRILMLGLDAAGKTTLLYKMKLGQ-SVTXIPTVGFNVETVSFKNVN----SMSG 2468

Query: 75   QPRFRSMWERY 85
                R+ ++RY
Sbjct: 2467 M*VGRTKYDRY 2435
>18208
          Length = 458

 Score = 71.2 bits (173), Expect = 2e-13,   Method: Compositional matrix adjust.
 Identities = 32/88 (36%), Positives = 54/88 (61%)
 Frame = -1

Query: 20  EMELTLVGLQYSGKTTFVNVIASGQFSEDMIPTVGFNMRKVTKGNVTIKIWDIGGQPRFR 79
           E+ + L+GL  +GKTT +  +AS   S  + PT GFN++ V      + +WDIGGQ R R
Sbjct: 302 ELRILLLGLDNAGKTTLLKQLASEDPSH-ITPTQGFNIKSVQSKGFKLNVWDIGGQRRIR 126

Query: 80  SMWERYCRGVNAIVYMIDAADREKIEAS 107
             W+ Y    + ++Y+ID++D +++E +
Sbjct: 125 PYWKNYFENTDLLIYVIDSSDTKRMEET 42
>18949
          Length = 414

 Score = 67.4 bits (163), Expect = 3e-12,   Method: Compositional matrix adjust.
 Identities = 39/128 (30%), Positives = 64/128 (50%), Gaps = 8/128 (6%)
 Frame = +3

Query: 51  PTVGFNMRKVTKGNVTIKIWDIGGQPRFRSMWERYCRGVNAIVYMIDAADREKIEASRNE 110
           PT      +++ G +T   +D+GG  + R +W+ Y   V+ IV+++D  D E+I  ++ E
Sbjct: 15  PTGLPTSEELSMGGMTFTTFDLGGHRQARRVWKDYFPAVDGIVFIVDVHDTERITEAKAE 194

Query: 111 LHNLLDKPQLQGIPVLVLGNKRDLPNALDEKQLIEKMNLSAIQDREICC--------YSI 162
           L +LL   Q+  IPVLVLGNK D    ++ +        +A+Q R            +S 
Sbjct: 195 LDSLLRDDQIADIPVLVLGNKMDKHGVVERRTSDTGWACTALQARTKRATVN*QEDRWSC 374

Query: 163 SCKEKDNI 170
           SC    N+
Sbjct: 375 SCAASSNV 398
>33605
          Length = 888

 Score = 66.6 bits (161), Expect = 5e-12,   Method: Compositional matrix adjust.
 Identities = 29/87 (33%), Positives = 54/87 (62%)
 Frame = +1

Query: 18  KEEMELTLVGLQYSGKTTFVNVIASGQFSEDMIPTVGFNMRKVTKGNVTIKIWDIGGQPR 77
           ++E+ L ++GL  +GKTT +    +G+  + + PT+GFN++ +      + +WD+GGQ  
Sbjct: 490 EKEVRLLMLGLDNAGKTTILKKF-NGEDIDTISPTLGFNIKTLEHRGFKLNVWDVGGQQS 666

Query: 78  FRSMWERYCRGVNAIVYMIDAADREKI 104
            RS W  Y    + +V+++D+ADR +I
Sbjct: 667 LRSYWRNYFESTDGLVWVVDSADRMRI 747
>15662
          Length = 455

 Score = 57.0 bits (136), Expect = 5e-09,   Method: Compositional matrix adjust.
 Identities = 26/74 (35%), Positives = 43/74 (58%)
 Frame = +2

Query: 79  RSMWERYCRGVNAIVYMIDAADREKIEASRNELHNLLDKPQLQGIPVLVLGNKRDLPNAL 138
           R +W+ Y   V+ IV+++D  DRE+   ++ EL +L+   Q+   P+LVLGNK D P A 
Sbjct: 8   RRVWKDYFPAVDGIVFLVDVHDRERFVEAKAELDSLMTDEQVANAPILVLGNKIDKPGAA 187

Query: 139 DEKQLIEKMNLSAI 152
            E ++     L ++
Sbjct: 188 SEDEIRHWFGLHSL 229
>34468
          Length = 1502

 Score = 52.4 bits (124), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 35/124 (28%), Positives = 60/124 (48%), Gaps = 10/124 (8%)
 Frame = +1

Query: 21  MELTLVGLQYSGKTTFVNVIASGQFSEDMIPTVGFNMR----KVTKGNVTIKIWDIGGQP 76
            ++ ++G    GKT        G+F +    T+G + R    +V   ++ +++WD  GQ 
Sbjct: 496 FKIIVIGDSNVGKTCLTYRFCLGKFPDKTEATIGVDFREKSIQVDSEHLKLQLWDTAGQE 675

Query: 77  RFR-SMWERYCRGVNAIVYMIDAADREKIE-----ASRNELHNLLDKPQLQGIPVLVLGN 130
           RFR SM + Y R V+A+V++ D       E         + HNL      + IP +++GN
Sbjct: 676 RFRKSMVQHYYRNVHAVVFVYDMTKMSSFENMPAWIEECDRHNL-----TKYIPRILVGN 840

Query: 131 KRDL 134
           K D+
Sbjct: 841 KCDV 852
>17511
          Length = 483

 Score = 49.7 bits (117), Expect = 7e-07,   Method: Compositional matrix adjust.
 Identities = 34/121 (28%), Positives = 61/121 (50%), Gaps = 7/121 (5%)
 Frame = -3

Query: 21  MELTLVGLQYSGKTTFVNVIASGQFSEDMIPTVG--FNMRKVTKGN--VTIKIWDIGGQP 76
           +++ ++G    GKT+ +N   + +FS     T+G  F  ++V   +  VT++IWD  GQ 
Sbjct: 364 LKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQIWDTAGQE 185

Query: 77  RFRSMWERYCRGVNAIVYMIDAA---DREKIEASRNELHNLLDKPQLQGIPVLVLGNKRD 133
           RF+S+   + RG +  V + D         +++ R+E          +  P +V+GNK D
Sbjct: 184 RFQSLGVAFYRGADCCVLVFDVTMPNTFRSLDSWRDEFLIQASPRDPENFPFVVIGNKID 5

Query: 134 L 134
           L
Sbjct: 4   L 2
>13901
          Length = 962

 Score = 48.1 bits (113), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 26/90 (28%), Positives = 44/90 (48%), Gaps = 5/90 (5%)
 Frame = -3

Query: 21  MELTLVGLQYSGKTTFVNVIASGQFSEDMIPTVGFN-----MRKVTKGNVTIKIWDIGGQ 75
            ++ ++G    GKT+FV    +  F  D   T+G +     +R   K N+ +++WDI GQ
Sbjct: 285 FKVIIIGDPTVGKTSFVQRYVNDSFRRDYKMTIGVDFALKVIRWSDKCNIKLQLWDIAGQ 106

Query: 76  PRFRSMWERYCRGVNAIVYMIDAADREKIE 105
            RF SM   Y +  +A + M D   +   +
Sbjct: 105 ERFTSMTRVYYKDAHACIVMFDLTQKNTYQ 16
>19006
          Length = 568

 Score = 47.8 bits (112), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 38/143 (26%), Positives = 68/143 (47%), Gaps = 11/143 (7%)
 Frame = -2

Query: 22  ELTLVGLQYSGKTTFVNVIASGQFSEDMIPTVGFNMR---KVTKGNVTIKIWDIGGQPRF 78
           +L +VG    GKT  + V +  QF E  +PTV  N     +V    V + +WD  GQ  +
Sbjct: 432 KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDSKQVELALWDTAGQEDY 253

Query: 79  RSMWERYCRGVNAIV--YMIDAADREKIEASRNELHNLLDK--PQLQ----GIPVLVLGN 130
             +        + I+  + ID+ D          L N+ +K  P+++     +P++++GN
Sbjct: 252 DRLRPLSYPDTDVILMCFSIDSPD---------SLENIPEKWTPEVRHFCPNVPIILVGN 100

Query: 131 KRDLPNALDEKQLIEKMNLSAIQ 153
           K+DL N  + K+ + KM    ++
Sbjct: 99  KKDLRNDENTKRELMKMKQEPVR 31
>14456
          Length = 1867

 Score = 45.1 bits (105), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 30/110 (27%), Positives = 48/110 (43%), Gaps = 7/110 (6%)
 Frame = -1

Query: 32   GKTTFVNVIASGQFSEDMIPTVGFNMRK----VTKGNVTIKIWDIGGQPRFRSMWERYCR 87
            GK++ +N   S +F      T+G         V     T++IWD  GQ RF+S+   + R
Sbjct: 1105 GKSSLMNRFVSNKFDAQSFHTIGVEFLNKDVVVDDETYTMQIWDTAGQERFKSLRTPFYR 926

Query: 88   GVNA--IVYMIDAADR-EKIEASRNELHNLLDKPQLQGIPVLVLGNKRDL 134
            G +   + + +D+      +   R E     D       P +VLGNK D+
Sbjct: 925  GADCCLLTFSVDSMQSFRNLSMWRKEFLYYADIQDGVTFPFVVLGNKIDV 776
>07465
          Length = 1103

 Score = 44.7 bits (104), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 38/153 (24%), Positives = 69/153 (45%), Gaps = 9/153 (5%)
 Frame = +3

Query: 34  TTFVNVIASGQFSEDMIPTVGFNM--RKVTKG--NVTIKIWDIGGQPRFRSMWERYCRGV 89
           ++ +     G F++D   T+G +   R++  G  +V + +WD  GQ  F ++ + Y RG 
Sbjct: 240 SSMIQRYCKGIFTKDYKKTIGVDFLERQIEVGGEDVRLMLWDTAGQEEFDAITKAYYRGA 419

Query: 90  NAIVYMIDAADREKIEASRNELHNLLDKPQLQGIPVLVLGNKRDLPNAL-----DEKQLI 144
            A V      DR+  EA       + D  ++  I ++++ NK DL +       + + L 
Sbjct: 420 QACVLAFSTVDRDSFEALETWKRKVED--EVGEIGMVIVQNKIDLIDDAVVRPEEAENLA 593

Query: 145 EKMNLSAIQDREICCYSISCKEKDNIDITLQWL 177
           +K+ L          Y  S KE  N+D   ++L
Sbjct: 594 KKLRLR--------FYRTSVKENMNVDEVFRYL 668
>13750
          Length = 503

 Score = 42.7 bits (99), Expect = 8e-05,   Method: Compositional matrix adjust.
 Identities = 30/110 (27%), Positives = 47/110 (42%), Gaps = 8/110 (7%)
 Frame = -2

Query: 33  KTTFVNVIASGQFSEDMIPTVG-----FNMRKVTKGNVTIKIWDIGGQPRFRSMWERYCR 87
           KT  +     G F +  +PT+      FN  +    NV   +WD GG   +RS+W  + R
Sbjct: 502 KTCLLRRYQKGFFMDRTMPTIAVLCSEFNESRTDPLNVRYTLWDTGGAETYRSLWVSHFR 323

Query: 88  GVNAIVYMIDAADREKIEASRNELHNLLDKPQLQGIP---VLVLGNKRDL 134
           G    + + D       E S      +  K  ++ IP   V+ +G+K DL
Sbjct: 322 GAQVALLVYDVT----CEWSFLTATTVWRKALMKNIPEAQVIFVGSKTDL 185
>33380
          Length = 282

 Score = 40.8 bits (94), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 21/72 (29%), Positives = 35/72 (48%)
 Frame = +3

Query: 65  VTIKIWDIGGQPRFRSMWERYCRGVNAIVYMIDAADREKIEASRNELHNLLDKPQLQGIP 124
           V ++IWD  GQ R+R++   Y RG    + M D  + E   A ++     +         
Sbjct: 60  VKLQIWDTAGQERYRTITTAYYRGAMGFILMYDVTNEESFNAVQDWCTQ-IKTYSWDNAQ 236

Query: 125 VLVLGNKRDLPN 136
           V+++GNK DL +
Sbjct: 237 VVLVGNKCDLED 272
>08428
          Length = 1109

 Score = 40.4 bits (93), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 34/122 (27%), Positives = 57/122 (46%), Gaps = 7/122 (5%)
 Frame = -3

Query: 20   EMELTLVGLQYSGKTTFVNVIASGQFSEDMIPTVGFN-MRK---VTKGNVTIKIWDIGGQ 75
            ++++ L+G    GK++ V    +G +      T+G + M K   V       +IWD  GQ
Sbjct: 1071 DVKVCLLGDSGVGKSSIVLRFVTGSYRPSQESTIGASFMSKSLVVDGAGYRFQIWDTAGQ 892

Query: 76   PRFRSMWERYCRGVNAIVYMIDAADREKIEASRNELHNLLDKPQLQGIPVLVL---GNKR 132
             +FR++   Y RG  A V + D       ++ ++ +  L    +  G P +VL   GNK 
Sbjct: 891  EKFRALAPMYYRGAAAAVIVYDVTRPRTFKSVKSWIQEL----RSFGPPNIVLAIAGNKC 724

Query: 133  DL 134
            DL
Sbjct: 723  DL 718
>26083
          Length = 432

 Score = 40.0 bits (92), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 25/87 (28%), Positives = 39/87 (44%), Gaps = 6/87 (6%)
 Frame = +1

Query: 20  EMELTLVGLQYSGKTTFVNVIASGQFSEDMIPTVGFNMRKVT----KGNVTIKIWDIGGQ 75
           + +L  +G Q  GKT+ +       F      T+G +    T       + +++WD  GQ
Sbjct: 76  KFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTIRLQLWDTAGQ 255

Query: 76  PRFRSMWERYCR--GVNAIVYMIDAAD 100
            RFRS+   Y R   V  +VY I  A+
Sbjct: 256 ERFRSLIPSYIRDSSVAVVVYDITNAN 336
>35581
          Length = 364

 Score = 40.0 bits (92), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 23/85 (27%), Positives = 43/85 (50%), Gaps = 5/85 (5%)
 Frame = +2

Query: 25  LVGLQYSGKTTFVNVIASGQFSEDMIPTVG----FNMRKVTKG-NVTIKIWDIGGQPRFR 79
           L+G    GKT  +N +A+ +F +  + ++          +T G   ++ +WD  GQ R+R
Sbjct: 59  LLGDAGVGKTCLLNRLATDKFLDSPLTSLTTASLLTTVTLTSGVMASVDLWDTAGQERYR 238

Query: 80  SMWERYCRGVNAIVYMIDAADREKI 104
           S+   Y R   A++ + DA  + K+
Sbjct: 239 SLTSSYYRDTKAVLIVYDAEHKLKL 313
>14775
          Length = 380

 Score = 38.9 bits (89), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 20/70 (28%), Positives = 31/70 (44%), Gaps = 5/70 (7%)
 Frame = -2

Query: 33  KTTFVNVIASGQFSEDMIPTVG-----FNMRKVTKGNVTIKIWDIGGQPRFRSMWERYCR 87
           KT  +     G F +  +PT+      FN  +    NV   +WD GG   +RS+W  + R
Sbjct: 379 KTCLLRRYQKGFFMDRTMPTIAVLCSEFNESRTDPLNVRYTLWDTGGAETYRSLWVSHFR 200

Query: 88  GVNAIVYMID 97
           G    + + D
Sbjct: 199 GAQVALLVYD 170
>01972
          Length = 2359

 Score = 30.8 bits (68), Expect = 0.31,   Method: Compositional matrix adjust.
 Identities = 14/31 (45%), Positives = 20/31 (64%)
 Frame = +1

Query: 21  MELTLVGLQYSGKTTFVNVIASGQFSEDMIP 51
            +L LVG    GKTTFV    +G+F ++M+P
Sbjct: 304 FKLVLVGDGGVGKTTFVKRHVTGEFEKNMLP 396
>00858
          Length = 1658

 Score = 30.8 bits (68), Expect = 0.33,   Method: Compositional matrix adjust.
 Identities = 27/109 (24%), Positives = 47/109 (43%), Gaps = 6/109 (5%)
 Frame = -2

Query: 33   KTTFVNVIASGQFSEDMIPTVGFNMRK--VTKGNVTI-KIWDIGGQPRFRSMWERYCR-- 87
            K+     +    F E+  PT   + RK  V  G   +  I D  GQ    +M ++  R  
Sbjct: 1552 KSALTIQLXQNHFVEEYDPTXEDSXRKQVVIDGETCLLDILDTAGQEEXSAMRDQCMRTG 1373

Query: 88   -GVNAIVYMIDAADREKIEASRNELHNLLDKPQLQGIPVLVLGNKRDLP 135
             G   +  + +    E I   R ++  + D  +   +P++++GNK DLP
Sbjct: 1372 EGFLCVFAVXNLKSFEDINQYREQIKRVKDADE---VPMVLVGNKVDLP 1235
>10708
          Length = 2775

 Score = 26.6 bits (57), Expect = 6.8,   Method: Compositional matrix adjust.
 Identities = 10/32 (31%), Positives = 21/32 (65%)
 Frame = -3

Query: 122  GIPVLVLGNKRDLPNALDEKQLIEKMNLSAIQ 153
             +P++++GNK+DL N  + K+ + KM    ++
Sbjct: 2554 NVPIILVGNKKDLRNDENTKRELMKMKQEPVR 2459
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|165377206|ref|NP_080241.3| signal sequence receptor,
alpha [Mus musculus]
         (286 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

01190                                                                 199   1e-51
13549                                                                 189   1e-48
19010                                                                  28   5.0  
>01190
          Length = 1210

 Score =  199 bits (506), Expect = 1e-51,   Method: Compositional matrix adjust.
 Identities = 100/196 (51%), Positives = 131/196 (66%), Gaps = 7/196 (3%)
 Frame = -3

Query: 78  EASPSADTTILFVK----GEDFPANNIVKFLVGFTNKGTEDFIVESLDASFRYPQDYQFY 133
           ++SP ADT ILF K    G++ PA   V+ LVGFTNKG  +F+VES++ASFRYPQDY +Y
Sbjct: 755 KSSPDADTFILFTKPVGNGQELPAGKPVRLLVGFTNKGYGEFVVESMEASFRYPQDYSYY 576

Query: 134 IQNFTALPLNTVVPPQRQATFEYSFIPAEPMGGRPFGLVINLNYKDLNGNVFQDAVFNQT 193
           +QN+T + LN  V  +RQATFEYSFIP E    RPFGL +N+NYKD   N FQ AVFN+T
Sbjct: 575 LQNYTTVSLNRQVESKRQATFEYSFIPNEAFSARPFGLTVNINYKDGQDNQFQTAVFNET 396

Query: 194 VTVIEREDGLDGETIFMYMFXXXXXXXXXXXXXXXXESRKRKR---PIQKVEMGTSSQND 250
           + V+E ++GLDGET F+Y+F                 S  +KR   P Q VEMGT +  D
Sbjct: 395 IQVVEPDEGLDGETFFLYVFLAALAILLCVGAQQLVSSLGKKRKSKPRQAVEMGTQN-GD 219

Query: 251 VDMSWIPQETLNQINK 266
           +D  WIP+ET+ ++N+
Sbjct: 218 IDYDWIPKETIKEMNR 171
>13549
          Length = 1298

 Score =  189 bits (479), Expect = 1e-48,   Method: Compositional matrix adjust.
 Identities = 97/191 (50%), Positives = 124/191 (64%), Gaps = 9/191 (4%)
 Frame = -1

Query: 78  EASPSADTTILFVK----GEDFPANNIVKFLVGFTNKGTEDFIVESLDASFRYPQDYQFY 133
           +ASP AD  I F+K    G + PA   V+ LVGFTNKG  +F+VE+++ASFRYPQDY FY
Sbjct: 959 KASPDADAIIQFIKPTGNGHELPAGKNVRLLVGFTNKGYGEFVVENMEASFRYPQDYSFY 780

Query: 134 IQNFTALPLNTVVPPQRQATFEYSFIPAEPMGGRPFGLVINLNYKDLNGNVFQDAVFNQT 193
           +QNFT +  N VV  +RQATFEY FIP E    RPFGL +N+NYKD  GN FQ+AVFN+T
Sbjct: 779 LQNFTTVTFNRVVESKRQATFEYGFIPNEAFSSRPFGLTVNINYKDGQGNQFQNAVFNET 600

Query: 194 VTVIEREDGLDGETIFMYMFXXXXXXXXXXXXXXXXES-----RKRKRPIQKVEMGTSSQ 248
           + V+E ++GLDGET F+Y+F                 S     R + RP+  VEMGT + 
Sbjct: 599 IQVVEPDEGLDGETFFLYVFLAAIGILLLVGAQQLVASLGKKHRSKARPV--VEMGTQNA 426

Query: 249 NDVDMSWIPQE 259
            D+D  WIP+E
Sbjct: 425 -DIDYDWIPKE 396
>19010
          Length = 864

 Score = 27.7 bits (60), Expect = 5.0,   Method: Compositional matrix adjust.
 Identities = 12/29 (41%), Positives = 18/29 (62%)
 Frame = -1

Query: 159 IPAEPMGGRPFGLVINLNYKDLNGNVFQD 187
           +P+EP+ G P  +  N NY +LN  +F D
Sbjct: 687 LPSEPL*GHPIYICNN*NYVNLNQYLFCD 601
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|23956194|ref|NP_081099.1| ADP-ribosylation
factor-like 8A [Mus musculus]
         (186 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

15973                                                                 198   1e-51
09827                                                                 115   9e-27
08153                                                                 109   7e-25
30944                                                                  94   4e-20
11378                                                                  84   3e-17
10862                                                                  81   3e-16
18949                                                                  71   3e-13
18208                                                                  68   2e-12
33605                                                                  65   2e-11
15662                                                                  56   9e-09
34468                                                                  52   1e-07
13901                                                                  48   2e-06
14456                                                                  45   2e-05
19006                                                                  45   2e-05
26083                                                                  44   4e-05
13750                                                                  44   5e-05
08428                                                                  43   7e-05
35581                                                                  40   4e-04
33380                                                                  40   4e-04
14775                                                                  40   7e-04
27191                                                                  35   0.017
01972                                                                  32   0.21 
19506                                                                  28   1.9  
>15973
          Length = 493

 Score =  198 bits (503), Expect = 1e-51,   Method: Compositional matrix adjust.
 Identities = 93/103 (90%), Positives = 101/103 (98%)
 Frame = -1

Query: 83  ERYCRGVSAIVYMVDAADQEKIEASKNELHNLLDKPQLQGIPVLVLGNKRDLAGALDEKE 142
           ERYCRGV+AIVYMVDAADQ+K+EAS+NELHNLLDKPQLQG+PVLVLGNKRDL GALDEKE
Sbjct: 493 ERYCRGVNAIVYMVDAADQDKLEASRNELHNLLDKPQLQGVPVLVLGNKRDLPGALDEKE 314

Query: 143 LIEKMNLSAIQDREICCYSISCKEKDNIDITLQWLIQHSKSRR 185
           LI++MNLSAIQDREICCYSISCKEK+NIDITLQWLIQHSKS R
Sbjct: 313 LIDRMNLSAIQDREICCYSISCKEKENIDITLQWLIQHSKSGR 185
>09827
          Length = 1201

 Score =  115 bits (289), Expect = 9e-27,   Method: Compositional matrix adjust.
 Identities = 55/182 (30%), Positives = 102/182 (56%)
 Frame = -3

Query: 5    FNKLLDWFKALFWKEEMELTLVGLQYSGKTTFVNVIASGQFNEDMIPTVGFNMRKITKGN 64
            F K+      +F K++M + +VGL  +GKTT +  +  G+     IPT+GFN+  +   N
Sbjct: 1160 FQKIFSGLSFMFGKKDMRILMVGLDAAGKTTILYKLKLGEI-VTTIPTIGFNVETVEYKN 984

Query: 65   VTIKLWDIGGQPRFRSMWERYCRGVSAIVYMVDAADQEKIEASKNELHNLLDKPQLQGIP 124
            ++  +WD+GGQ + R +W  Y +    ++++VD+ D+E+++ ++ EL  +L++ +L+   
Sbjct: 983  ISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDKERVQEAREELTRMLNEDELRDAV 804

Query: 125  VLVLGNKRDLAGALDEKELIEKMNLSAIQDREICCYSISCKEKDNIDITLQWLIQHSKSR 184
            +LV  NK+DL  A+   E+ EK+ L  +++R     S      D +   L WL    K+ 
Sbjct: 803  LLVFANKQDLPHAMATAEITEKLGLHGLRNRTWYIQSTCATTGDGLYEGLDWLSNQLKNN 624

Query: 185  RS 186
            +S
Sbjct: 623  KS 618
>08153
          Length = 1703

 Score =  109 bits (272), Expect = 7e-25,   Method: Compositional matrix adjust.
 Identities = 53/166 (31%), Positives = 94/166 (56%)
 Frame = +1

Query: 12  FKALFWKEEMELTLVGLQYSGKTTFVNVIASGQFNEDMIPTVGFNMRKITKGNVTIKLWD 71
           FK LF K+E+ + +VGL  +GKTT +  +  G+     IPT+GFN+  +   N++  +WD
Sbjct: 58  FKNLFGKKEVRILMVGLDAAGKTTILYKLKLGEI-VTTIPTIGFNVETVEYKNISFTVWD 234

Query: 72  IGGQPRFRSMWERYCRGVSAIVYMVDAADQEKIEASKNELHNLLDKPQLQGIPVLVLGNK 131
           +GGQ + R +W  Y +    ++++VD+ D+E+I  +K EL  +L++  L+   +LV  NK
Sbjct: 235 VGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERINEAKEELARMLNEDDLRDAIILVFANK 414

Query: 132 RDLAGALDEKELIEKMNLSAIQDREICCYSISCKEKDNIDITLQWL 177
           +DL  A    E+   + L+ ++ R+    +      D +   L+WL
Sbjct: 415 QDLPNAYSASEVTAHLGLANLKGRKWYMQATCATSGDGMYEGLEWL 552
>30944
          Length = 1058

 Score = 94.0 bits (232), Expect = 4e-20,   Method: Compositional matrix adjust.
 Identities = 44/49 (89%), Positives = 48/49 (97%)
 Frame = +1

Query: 137 ALDEKELIEKMNLSAIQDREICCYSISCKEKDNIDITLQWLIQHSKSRR 185
           ALDEK+LIE+MNL+AIQDREICCYSISCKEK+NIDITLQWLIQHSKS R
Sbjct: 1   ALDEKDLIERMNLAAIQDREICCYSISCKEKENIDITLQWLIQHSKSGR 147
>11378
          Length = 1688

 Score = 84.3 bits (207), Expect = 3e-17,   Method: Compositional matrix adjust.
 Identities = 45/150 (30%), Positives = 85/150 (56%), Gaps = 5/150 (3%)
 Frame = +3

Query: 8   LLDWFKALF-----WKEEMELTLVGLQYSGKTTFVNVIASGQFNEDMIPTVGFNMRKITK 62
           L +WF+ +      +K+  +L  +GL  +GKTT ++++   +  +  +PT+     +++ 
Sbjct: 270 LWNWFQDMLSFLGLYKKSGKLVFLGLDNAGKTTLLHMLKDDKMAQH-VPTLHPTSEELSM 446

Query: 63  GNVTIKLWDIGGQPRFRSMWERYCRGVSAIVYMVDAADQEKIEASKNELHNLLDKPQLQG 122
           G +    +D+GG  + R +W+ Y   V  IV++VD  D+E++  +K EL +L+   Q+  
Sbjct: 447 GGMRFTTFDLGGHRQARRVWKDYFPAVDGIVFLVDVHDRERLVEAKAELDSLMTDEQVAN 626

Query: 123 IPVLVLGNKRDLAGALDEKELIEKMNLSAI 152
            P+LVLGNK D  GA  E+E+     L+++
Sbjct: 627 APILVLGNKIDKPGAASEEEIRHWFGLNSL 716
>10862
          Length = 2896

 Score = 80.9 bits (198), Expect = 3e-16,   Method: Compositional matrix adjust.
 Identities = 35/115 (30%), Positives = 66/115 (57%)
 Frame = -3

Query: 69   LWDIGGQPRFRSMWERYCRGVSAIVYMVDAADQEKIEASKNELHNLLDKPQLQGIPVLVL 128
            +WD+GGQ + R +W  Y  G   ++++VD AD+++I+ ++ ELH +++  +++   +L+ 
Sbjct: 2474 VWDVGGQDKIRPLWRHYYTGTQGLIFVVDCADRDRIDEARQELHRIINDREMRDAIILIF 2295

Query: 129  GNKRDLAGALDEKELIEKMNLSAIQDREICCYSISCKEKDNIDITLQWLIQHSKS 183
             NK+DL  A+   E+ EK+ L+ ++DR            D +   L WL  + KS
Sbjct: 2294 ANKQDLPDAMKPHEIQEKLGLTRLRDRNWYVQPSCATTGDGLCEGLTWLTSNHKS 2130

 Score = 38.9 bits (89), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 24/71 (33%), Positives = 40/71 (56%)
 Frame = -1

Query: 15   LFWKEEMELTLVGLQYSGKTTFVNVIASGQFNEDMIPTVGFNMRKITKGNVTIKLWDIGG 74
            +F  +EM + ++GL  +GKTT +  +  GQ +   IPTVGFN+  ++  NV      + G
Sbjct: 2632 IFGNKEMRILMLGLDAAGKTTLLYKMKLGQ-SVTXIPTVGFNVETVSFKNVN----SMSG 2468

Query: 75   QPRFRSMWERY 85
                R+ ++RY
Sbjct: 2467 M*VGRTKYDRY 2435
>18949
          Length = 414

 Score = 70.9 bits (172), Expect = 3e-13,   Method: Compositional matrix adjust.
 Identities = 42/128 (32%), Positives = 64/128 (50%), Gaps = 8/128 (6%)
 Frame = +3

Query: 51  PTVGFNMRKITKGNVTIKLWDIGGQPRFRSMWERYCRGVSAIVYMVDAADQEKIEASKNE 110
           PT      +++ G +T   +D+GG  + R +W+ Y   V  IV++VD  D E+I  +K E
Sbjct: 15  PTGLPTSEELSMGGMTFTTFDLGGHRQARRVWKDYFPAVDGIVFIVDVHDTERITEAKAE 194

Query: 111 LHNLLDKPQLQGIPVLVLGNKRDLAGALDEKELIEKMNLSAIQDREICC--------YSI 162
           L +LL   Q+  IPVLVLGNK D  G ++ +        +A+Q R            +S 
Sbjct: 195 LDSLLRDDQIADIPVLVLGNKMDKHGVVERRTSDTGWACTALQARTKRATVN*QEDRWSC 374

Query: 163 SCKEKDNI 170
           SC    N+
Sbjct: 375 SCAASSNV 398
>18208
          Length = 458

 Score = 68.2 bits (165), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 29/88 (32%), Positives = 53/88 (60%)
 Frame = -1

Query: 20  EMELTLVGLQYSGKTTFVNVIASGQFNEDMIPTVGFNMRKITKGNVTIKLWDIGGQPRFR 79
           E+ + L+GL  +GKTT +  +AS +    + PT GFN++ +      + +WDIGGQ R R
Sbjct: 302 ELRILLLGLDNAGKTTLLKQLAS-EDPSHITPTQGFNIKSVQSKGFKLNVWDIGGQRRIR 126

Query: 80  SMWERYCRGVSAIVYMVDAADQEKIEAS 107
             W+ Y      ++Y++D++D +++E +
Sbjct: 125 PYWKNYFENTDLLIYVIDSSDTKRMEET 42
>33605
          Length = 888

 Score = 65.1 bits (157), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 30/93 (32%), Positives = 55/93 (59%)
 Frame = +1

Query: 18  KEEMELTLVGLQYSGKTTFVNVIASGQFNEDMIPTVGFNMRKITKGNVTIKLWDIGGQPR 77
           ++E+ L ++GL  +GKTT +    +G+  + + PT+GFN++ +      + +WD+GGQ  
Sbjct: 490 EKEVRLLMLGLDNAGKTTILKKF-NGEDIDTISPTLGFNIKTLEHRGFKLNVWDVGGQQS 666

Query: 78  FRSMWERYCRGVSAIVYMVDAADQEKIEASKNE 110
            RS W  Y      +V++VD+AD+ +I   K +
Sbjct: 667 LRSYWRNYFESTDGLVWVVDSADRMRIADCKRD 765
>15662
          Length = 455

 Score = 55.8 bits (133), Expect = 9e-09,   Method: Compositional matrix adjust.
 Identities = 28/74 (37%), Positives = 42/74 (56%)
 Frame = +2

Query: 79  RSMWERYCRGVSAIVYMVDAADQEKIEASKNELHNLLDKPQLQGIPVLVLGNKRDLAGAL 138
           R +W+ Y   V  IV++VD  D+E+   +K EL +L+   Q+   P+LVLGNK D  GA 
Sbjct: 8   RRVWKDYFPAVDGIVFLVDVHDRERFVEAKAELDSLMTDEQVANAPILVLGNKIDKPGAA 187

Query: 139 DEKELIEKMNLSAI 152
            E E+     L ++
Sbjct: 188 SEDEIRHWFGLHSL 229
>34468
          Length = 1502

 Score = 52.4 bits (124), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 35/124 (28%), Positives = 60/124 (48%), Gaps = 10/124 (8%)
 Frame = +1

Query: 21  MELTLVGLQYSGKTTFVNVIASGQFNEDMIPTVGFNMR----KITKGNVTIKLWDIGGQP 76
            ++ ++G    GKT        G+F +    T+G + R    ++   ++ ++LWD  GQ 
Sbjct: 496 FKIIVIGDSNVGKTCLTYRFCLGKFPDKTEATIGVDFREKSIQVDSEHLKLQLWDTAGQE 675

Query: 77  RFR-SMWERYCRGVSAIVYMVDAADQEKIE-----ASKNELHNLLDKPQLQGIPVLVLGN 130
           RFR SM + Y R V A+V++ D       E       + + HNL      + IP +++GN
Sbjct: 676 RFRKSMVQHYYRNVHAVVFVYDMTKMSSFENMPAWIEECDRHNL-----TKYIPRILVGN 840

Query: 131 KRDL 134
           K D+
Sbjct: 841 KCDV 852
>13901
          Length = 962

 Score = 48.1 bits (113), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 27/82 (32%), Positives = 41/82 (50%), Gaps = 5/82 (6%)
 Frame = -3

Query: 21  MELTLVGLQYSGKTTFVNVIASGQFNEDMIPTVGFN-----MRKITKGNVTIKLWDIGGQ 75
            ++ ++G    GKT+FV    +  F  D   T+G +     +R   K N+ ++LWDI GQ
Sbjct: 285 FKVIIIGDPTVGKTSFVQRYVNDSFRRDYKMTIGVDFALKVIRWSDKCNIKLQLWDIAGQ 106

Query: 76  PRFRSMWERYCRGVSAIVYMVD 97
            RF SM   Y +   A + M D
Sbjct: 105 ERFTSMTRVYYKDAHACIVMFD 40
>14456
          Length = 1867

 Score = 45.1 bits (105), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 29/112 (25%), Positives = 49/112 (43%), Gaps = 7/112 (6%)
 Frame = -1

Query: 32   GKTTFVNVIASGQFNEDMIPTVGFNMRK----ITKGNVTIKLWDIGGQPRFRSMWERYCR 87
            GK++ +N   S +F+     T+G         +     T+++WD  GQ RF+S+   + R
Sbjct: 1105 GKSSLMNRFVSNKFDAQSFHTIGVEFLNKDVVVDDETYTMQIWDTAGQERFKSLRTPFYR 926

Query: 88   GVSA--IVYMVDAADQ-EKIEASKNELHNLLDKPQLQGIPVLVLGNKRDLAG 136
            G     + + VD+      +   + E     D       P +VLGNK D+ G
Sbjct: 925  GADCCLLTFSVDSMQSFRNLSMWRKEFLYYADIQDGVTFPFVVLGNKIDVEG 770
>19006
          Length = 568

 Score = 44.7 bits (104), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 36/143 (25%), Positives = 65/143 (45%), Gaps = 11/143 (7%)
 Frame = -2

Query: 22  ELTLVGLQYSGKTTFVNVIASGQFNEDMIPTVGFNMR---KITKGNVTIKLWDIGGQPRF 78
           +L +VG    GKT  + V +  QF E  +PTV  N     ++    V + LWD  GQ  +
Sbjct: 432 KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDSKQVELALWDTAGQEDY 253

Query: 79  RSMWERYCRGVSAIV--YMVDAADQEKIEASKNELHNLLDK--PQLQ----GIPVLVLGN 130
             +          I+  + +D+ D          L N+ +K  P+++     +P++++GN
Sbjct: 252 DRLRPLSYPDTDVILMCFSIDSPDS---------LENIPEKWTPEVRHFCPNVPIILVGN 100

Query: 131 KRDLAGALDEKELIEKMNLSAIQ 153
           K+DL    + K  + KM    ++
Sbjct: 99  KKDLRNDENTKRELMKMKQEPVR 31
>26083
          Length = 432

 Score = 43.9 bits (102), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 27/117 (23%), Positives = 51/117 (43%), Gaps = 4/117 (3%)
 Frame = +1

Query: 19  EEMELTLVGLQYSGKTTFVNVIASGQFNEDMIPTVGFNMRKIT----KGNVTIKLWDIGG 74
            + +L  +G Q  GKT+ +       F+     T+G +    T       + ++LWD  G
Sbjct: 73  RKFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTIRLQLWDTAG 252

Query: 75  QPRFRSMWERYCRGVSAIVYMVDAADQEKIEASKNELHNLLDKPQLQGIPVLVLGNK 131
           Q RFRS+   Y R  S  V + D  +      +   + + +   +   + ++++GNK
Sbjct: 253 QERFRSLIPSYIRDSSVAVVVYDITNANSFHQTSKWIDD-VRTERGSDVIIMLVGNK 420
>13750
          Length = 503

 Score = 43.5 bits (101), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 31/110 (28%), Positives = 47/110 (42%), Gaps = 8/110 (7%)
 Frame = -2

Query: 33  KTTFVNVIASGQFNEDMIPTVG-----FNMRKITKGNVTIKLWDIGGQPRFRSMWERYCR 87
           KT  +     G F +  +PT+      FN  +    NV   LWD GG   +RS+W  + R
Sbjct: 502 KTCLLRRYQKGFFMDRTMPTIAVLCSEFNESRTDPLNVRYTLWDTGGAETYRSLWVSHFR 323

Query: 88  GVSAIVYMVDAADQEKIEASKNELHNLLDKPQLQGIP---VLVLGNKRDL 134
           G    + + D       E S      +  K  ++ IP   V+ +G+K DL
Sbjct: 322 GAQVALLVYDVT----CEWSFLTATTVWRKALMKNIPEAQVIFVGSKTDL 185
>08428
          Length = 1109

 Score = 43.1 bits (100), Expect = 7e-05,   Method: Compositional matrix adjust.
 Identities = 36/134 (26%), Positives = 65/134 (48%), Gaps = 7/134 (5%)
 Frame = -3

Query: 20   EMELTLVGLQYSGKTTFVNVIASGQFNEDMIPTVGFN-MRK---ITKGNVTIKLWDIGGQ 75
            ++++ L+G    GK++ V    +G +      T+G + M K   +       ++WD  GQ
Sbjct: 1071 DVKVCLLGDSGVGKSSIVLRFVTGSYRPSQESTIGASFMSKSLVVDGAGYRFQIWDTAGQ 892

Query: 76   PRFRSMWERYCRGVSAIVYMVDAADQEKIEASKNELHNLLDKPQLQGIPVLVL---GNKR 132
             +FR++   Y RG +A V + D       ++ K+ +  L    +  G P +VL   GNK 
Sbjct: 891  EKFRALAPMYYRGAAAAVIVYDVTRPRTFKSVKSWIQEL----RSFGPPNIVLAIAGNKC 724

Query: 133  DLAGALDEKELIEK 146
            DL    + +E++EK
Sbjct: 723  DLE---ELREVVEK 691
>35581
          Length = 364

 Score = 40.4 bits (93), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 24/85 (28%), Positives = 43/85 (50%), Gaps = 5/85 (5%)
 Frame = +2

Query: 25  LVGLQYSGKTTFVNVIASGQFNEDMIPTVG----FNMRKITKG-NVTIKLWDIGGQPRFR 79
           L+G    GKT  +N +A+ +F +  + ++          +T G   ++ LWD  GQ R+R
Sbjct: 59  LLGDAGVGKTCLLNRLATDKFLDSPLTSLTTASLLTTVTLTSGVMASVDLWDTAGQERYR 238

Query: 80  SMWERYCRGVSAIVYMVDAADQEKI 104
           S+   Y R   A++ + DA  + K+
Sbjct: 239 SLTSSYYRDTKAVLIVYDAEHKLKL 313
>33380
          Length = 282

 Score = 40.4 bits (93), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 20/70 (28%), Positives = 35/70 (50%)
 Frame = +3

Query: 65  VTIKLWDIGGQPRFRSMWERYCRGVSAIVYMVDAADQEKIEASKNELHNLLDKPQLQGIP 124
           V +++WD  GQ R+R++   Y RG    + M D  ++E   A ++     +         
Sbjct: 60  VKLQIWDTAGQERYRTITTAYYRGAMGFILMYDVTNEESFNAVQDWCTQ-IKTYSWDNAQ 236

Query: 125 VLVLGNKRDL 134
           V+++GNK DL
Sbjct: 237 VVLVGNKCDL 266
>14775
          Length = 380

 Score = 39.7 bits (91), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 24/71 (33%), Positives = 34/71 (47%), Gaps = 7/71 (9%)
 Frame = -2

Query: 33  KTTFVNVIASGQFNEDMIPTVG-----FNMRKITKGNVTIKLWDIGGQPRFRSMWERYCR 87
           KT  +     G F +  +PT+      FN  +    NV   LWD GG   +RS+W  + R
Sbjct: 379 KTCLLRRYQKGFFMDRTMPTIAVLCSEFNESRTDPLNVRYTLWDTGGAETYRSLWVSHFR 200

Query: 88  G--VSAIVYMV 96
           G  V+ +VY V
Sbjct: 199 GAQVALLVYDV 167
>27191
          Length = 443

 Score = 35.0 bits (79), Expect = 0.017,   Method: Compositional matrix adjust.
 Identities = 18/78 (23%), Positives = 34/78 (43%), Gaps = 4/78 (5%)
 Frame = +1

Query: 33  KTTFVNVIASGQFNEDMIPTV----GFNMRKITKGNVTIKLWDIGGQPRFRSMWERYCRG 88
           KT  +      +FN+   PTV    GF ++ +   ++ + +WD+ G   +  +      G
Sbjct: 1   KTCLIKHFCESKFNQGYQPTVGVDYGFKIQTVNGVDMRVHMWDLSGSNEYLDVRNELYTG 180

Query: 89  VSAIVYMVDAADQEKIEA 106
             AI  + D ++    EA
Sbjct: 181 SDAIFIVFDVSNTPSFEA 234
>01972
          Length = 2359

 Score = 31.6 bits (70), Expect = 0.21,   Method: Compositional matrix adjust.
 Identities = 17/51 (33%), Positives = 29/51 (56%)
 Frame = +1

Query: 1   MIALFNKLLDWFKALFWKEEMELTLVGLQYSGKTTFVNVIASGQFNEDMIP 51
           + A+F  L+   + +  +   +L LVG    GKTTFV    +G+F ++M+P
Sbjct: 244 IFAIFVDLVIRNQRMEQEPTFKLVLVGDGGVGKTTFVKRHVTGEFEKNMLP 396
>19506
          Length = 421

 Score = 28.5 bits (62), Expect = 1.9,   Method: Compositional matrix adjust.
 Identities = 15/47 (31%), Positives = 26/47 (55%)
 Frame = -3

Query: 14  ALFWKEEMELTLVGLQYSGKTTFVNVIASGQFNEDMIPTVGFNMRKI 60
            LF ++ + +   GL  +GKTT +  +  G+     IPT+GFN+  +
Sbjct: 155 TLFRQKPVTVIYFGLDAAGKTTLLYNLKLGEV-VTTIPTIGFNVETL 18
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|114326466|ref|NP_034370.2| ferritin light chain 1
[Mus musculus]
         (183 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

01705                                                                 197   2e-51
10129                                                                 187   3e-48
02986                                                                 187   3e-48
18531                                                                 116   2e-40
24807                                                                  48   2e-06
22965                                                                  30   0.38 
21777                                                                  30   0.52 
14113                                                                  30   0.74 
>01705
          Length = 1365

 Score =  197 bits (501), Expect = 2e-51,   Method: Compositional matrix adjust.
 Identities = 94/180 (52%), Positives = 129/180 (71%)
 Frame = -3

Query: 2    TSQIRQNYSTEVEAAVNRLVNLHLRASYTYLSLGFFFDRDDVALEGVGHFFRELAEEKRE 61
             SQ RQNY  E EA +NR +N+ L ASY Y S+ F+FDRDDVAL G   FFRE + E+RE
Sbjct: 1126 VSQCRQNYHAECEAGINRQINMELHASYCYQSMAFYFDRDDVALPGFAKFFREASVEERE 947

Query: 62   GAERLLEFQNDRGGRALFQDVQKPSQDEWGKTQEAMEAALAMEKNLNQALLDLHALGSAR 121
             AE+L++FQN RGGR + QD++KP +DEWG   +AM+ ALA+EK++NQ+LLDLH + S  
Sbjct: 946  HAEKLMKFQNQRGGRIVLQDIKKPDRDEWGTGLDAMQVALALEKSVNQSLLDLHDVASGH 767

Query: 122  ADPHLCDFLESHYLDKEVKLIKKMGNHLTNLRRVAGPQPAQTGAPQGSLGEYLFERLTLK 181
             D  + DFLE +YL ++V+ IK++G+H+TNL+RV       TG     LGEY+F++ TL+
Sbjct: 766  KDAQMTDFLEGNYLQEQVQSIKEIGDHITNLKRVG------TG-----LGEYMFDKETLQ 620
>10129
          Length = 988

 Score =  187 bits (474), Expect = 3e-48,   Method: Compositional matrix adjust.
 Identities = 88/175 (50%), Positives = 125/175 (71%)
 Frame = -2

Query: 3   SQIRQNYSTEVEAAVNRLVNLHLRASYTYLSLGFFFDRDDVALEGVGHFFRELAEEKREG 62
           SQ RQNY  E EA +NR VN+ L ASY Y S+ F+FDRDDVAL G   +F+  ++E+R  
Sbjct: 741 SQCRQNYHAESEAGINRQVNMELYASYCYQSMSFYFDRDDVALPGFAKYFKHQSDEERGH 562

Query: 63  AERLLEFQNDRGGRALFQDVQKPSQDEWGKTQEAMEAALAMEKNLNQALLDLHALGSARA 122
           AE+L++FQN RGGR + QD++KP +DEWG   +AM+ AL +EK++NQALLDLHA+  +  
Sbjct: 561 AEKLMKFQNQRGGRIVLQDIKKPDRDEWGTALDAMQVALGLEKSVNQALLDLHAVADSHK 382

Query: 123 DPHLCDFLESHYLDKEVKLIKKMGNHLTNLRRVAGPQPAQTGAPQGSLGEYLFER 177
           D  + DFLE +YL ++V+ IK++G+H+TNL+RV       TG     LGEY++++
Sbjct: 381 DAQMTDFLEGNYLQEQVESIKEIGDHITNLKRVG------TG-----LGEYMYDK 250
>02986
          Length = 1117

 Score =  187 bits (474), Expect = 3e-48,   Method: Compositional matrix adjust.
 Identities = 88/175 (50%), Positives = 125/175 (71%)
 Frame = +2

Query: 3   SQIRQNYSTEVEAAVNRLVNLHLRASYTYLSLGFFFDRDDVALEGVGHFFRELAEEKREG 62
           SQ RQNY  E EA +NR VN+ L ASY Y S+ F+FDRDDVAL G   +F+  ++E+R  
Sbjct: 356 SQCRQNYHAESEAGINRQVNMELYASYCYQSMSFYFDRDDVALPGFAKYFKHQSDEERGH 535

Query: 63  AERLLEFQNDRGGRALFQDVQKPSQDEWGKTQEAMEAALAMEKNLNQALLDLHALGSARA 122
           AE+L++FQN RGGR + QD++KP +DEWG   +AM+ AL +EK++NQALLDLHA+  +  
Sbjct: 536 AEKLMKFQNQRGGRIVLQDIKKPDRDEWGTALDAMQVALGLEKSVNQALLDLHAVADSHK 715

Query: 123 DPHLCDFLESHYLDKEVKLIKKMGNHLTNLRRVAGPQPAQTGAPQGSLGEYLFER 177
           D  + DFLE +YL ++V+ IK++G+H+TNL+RV       TG     LGEY++++
Sbjct: 716 DAQMTDFLEGNYLQEQVESIKEIGDHITNLKRVG------TG-----LGEYMYDK 847
>18531
          Length = 1472

 Score =  116 bits (290), Expect(2) = 2e-40,   Method: Compositional matrix adjust.
 Identities = 60/136 (44%), Positives = 94/136 (69%)
 Frame = -1

Query: 46   EGVGHFFRELAEEKREGAERLLEFQNDRGGRALFQDVQKPSQDEWGKTQEAMEAALAMEK 105
            +G+   F + + E+RE AE+L+E+QN RGGR L Q+V+KP +D+WG   EAM+AAL +EK
Sbjct: 1286 QGIP*VFLKQSREEREHAEKLMEYQNMRGGRVLLQEVKKPERDDWGTGLEAMQAALHLEK 1107

Query: 106  NLNQALLDLHALGSARADPHLCDFLESHYLDKEVKLIKKMGNHLTNLRRVAGPQPAQTGA 165
            ++NQ+LLDLHA   +  D  + DF+E  +L ++V+ IK++ + +++L+RV       TG 
Sbjct: 1106 SVNQSLLDLHACADSHNDAQMGDFIEGTFLKEQVESIKQISDFVSSLKRVG------TG- 948

Query: 166  PQGSLGEYLFERLTLK 181
                LGEYLF++ TL+
Sbjct: 947  ----LGEYLFDKETLQ 912

 Score = 66.2 bits (160), Expect(2) = 2e-40,   Method: Compositional matrix adjust.
 Identities = 28/49 (57%), Positives = 36/49 (73%)
 Frame = -2

Query: 3    SQIRQNYSTEVEAAVNRLVNLHLRASYTYLSLGFFFDRDDVALEGVGHF 51
            +Q+RQN+  E EA +NR +N+ L ASY YLS+ F FDRDDVAL+G   F
Sbjct: 1414 AQVRQNFHAECEAGINRQINIELHASYVYLSMAFHFDRDDVALKGFHEF 1268
>24807
          Length = 447

 Score = 48.1 bits (113), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 21/41 (51%), Positives = 30/41 (73%)
 Frame = +1

Query: 39  DRDDVALEGVGHFFRELAEEKREGAERLLEFQNDRGGRALF 79
           DRDDVAL G   +F+  ++E+R  AE+L++FQN RGGR + 
Sbjct: 166 DRDDVALPGFAKYFKHQSDEERGHAEKLMKFQNQRGGRIVL 288
>22965
          Length = 1794

 Score = 30.4 bits (67), Expect = 0.38,   Method: Compositional matrix adjust.
 Identities = 18/63 (28%), Positives = 29/63 (46%)
 Frame = +1

Query: 90  WGKTQEAMEAALAMEKNLNQALLDLHALGSARADPHLCDFLESHYLDKEVKLIKKMGNHL 149
           W      +  AL ME+ LN  L+ L    S   D HL   +E  ++  + + IKK+ + +
Sbjct: 520 WQHGIMGLSDALLMERTLNGYLIHLVETASQHKDAHLRHVVEDSFVTHQTERIKKLADLI 699

Query: 150 TNL 152
             L
Sbjct: 700 NRL 708
>21777
          Length = 680

 Score = 30.0 bits (66), Expect = 0.52,   Method: Compositional matrix adjust.
 Identities = 19/88 (21%), Positives = 41/88 (46%), Gaps = 6/88 (6%)
 Frame = +3

Query: 95  EAMEAALAMEKNLNQALLDLHALGSA------RADPHLCDFLESHYLDKEVKLIKKMGNH 148
           E++  AL  EK L    + +H   +         DP +  +L+ H+L K+ + ++K+  +
Sbjct: 222 ESLARALDNEKQLTLGAIHVHTSATHGTTQNREHDPEMAHYLQEHFLSKQAETVRKLSGY 401

Query: 149 LTNLRRVAGPQPAQTGAPQGSLGEYLFE 176
             +L ++   +       + SL  +LF+
Sbjct: 402 ANDLSKLVSVR-------EPSLNVFLFD 464
>14113
          Length = 816

 Score = 29.6 bits (65), Expect = 0.74,   Method: Compositional matrix adjust.
 Identities = 19/88 (21%), Positives = 45/88 (51%), Gaps = 6/88 (6%)
 Frame = +2

Query: 96  AMEAALAMEKNLNQALLDL--HALGSARA----DPHLCDFLESHYLDKEVKLIKKMGNHL 149
           A+E A  +E  + +++ +L     G+++     D HL D+L   YL++++   +++   +
Sbjct: 8   ALEDAFKLETEVTKSIRELIKTCEGTSKKADDNDYHLVDYLTGVYLEEQLNGQRELAGQI 187

Query: 150 TNLRRVAGPQPAQTGAPQGSLGEYLFER 177
           T L ++         +  G + E+LF++
Sbjct: 188 TTLEKMM--------SAHGEIAEFLFDK 247
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|149253088|ref|XP_890015.3| PREDICTED:
microtubule-actin crosslinking factor 1 isoform 2 [Mus musculus]
         (7412 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

02929                                                                 203   2e-51
19002                                                                 203   2e-51
29446                                                                 103   2e-21
19147                                                                 100   3e-20
17613                                                                  63   1e-13
34417                                                                  74   2e-12
09711                                                                  65   1e-09
05733                                                                  64   3e-09
19912                                                                  55   1e-06
23752                                                                  54   2e-06
32088                                                                  53   5e-06
09100                                                                  48   1e-04
18556                                                                  44   0.002
04951                                                                  43   0.006
18202                                                                  41   0.022
32371                                                                  27   0.038
26019                                                                  37   0.30 
17484                                                                  36   0.46 
07678                                                                  35   1.2  
35978                                                                  35   1.3  
17977                                                                  34   2.0  
26849                                                                  34   2.6  
22444                                                                  33   4.4  
>02929
          Length = 1353

 Score =  203 bits (517), Expect = 2e-51,   Method: Composition-based stats.
 Identities = 94/204 (46%), Positives = 143/204 (70%), Gaps = 2/204 (0%)
 Frame = +2

Query: 7020 LALERQRKLNDALDRLEELKEFANFDFDVWRKKYMRWMNHKKSRVMDFFRRIDKDQDGKI 7079
            +A+ER++ L DA + L+EL+ F NFDF+ WR KY++W+  KK RV DFFRR DKD DG +
Sbjct: 50   MAVERKKALQDAYEMLQELENFKNFDFESWRGKYLKWIQAKKFRVTDFFRRQDKDGDGFL 229

Query: 7080 TRQEFIDGILASKFPTTKLEMTAVADIFDRDGDGYIDYYEFVAALHPNK--DAYRPTTDA 7137
            T +EF++G++ S+FPT + E+ AV DIFDR+  G I+Y +FV AL P+K   + R  +D 
Sbjct: 230  TEEEFVNGMMQSRFPTNRTELNAVFDIFDREKRGLIEYKDFVDALKPDKFRTSSRAMSDD 409

Query: 7138 DKIEDEVTRQVAQCKCAKRFQVEQIGENKYRFFLGNQFGDSQQLRLVRILRSTVMVRVGG 7197
            + I+D + ++   C C ++F   ++ + KYR      FG+ Q++ LVR+L  +VMVRVGG
Sbjct: 410  EVIQDSIDQEANGCSCREQFTGYRVDKGKYR------FGEKQKIVLVRLLNKSVMVRVGG 571

Query: 7198 GWMALDEFLVKNDPCRARGRTNIE 7221
            GW+ L+EF + NDPC+A+GR++ +
Sbjct: 572  GWVPLEEFFLTNDPCKAKGRSSFD 643
>19002
          Length = 842

 Score =  203 bits (516), Expect = 2e-51,   Method: Compositional matrix adjust.
 Identities = 117/264 (44%), Positives = 160/264 (60%), Gaps = 15/264 (5%)
 Frame = -2

Query: 57  DGHNLISLLEV-LSGIKLPREKGRMRFHRLQNVQIALDFLKQRQVKLVNIRNDDITDGNP 115
           DG  L+ LLEV + G      KG+MR H L+NV  AL FL +++V L N+   DI DG+ 
Sbjct: 841 DGKMLMKLLEVRVRGEIASDXKGKMRIHCLENVDKALTFLHEQRVHLENMGAHDIVDGSS 662

Query: 116 KLTLGLIWTIILHFQISDIYIS--GESGDMSAKEKLLLWTQKVTAGYTGVKCTNFSSCWS 173
           +LTLGLIWTIIL FQI DI I     S   SAK+ LLLW Q  TAGY  V   NF++ W 
Sbjct: 661 RLTLGLIWTIILRFQIQDIMIEEVDNSETKSAKDALLLWCQMKTAGYPNVNVRNFTTSWR 482

Query: 174 DGKMFNALIHRYRPDLVDMERVQVQSNRENLEQAFEVAE-RLGVTRLLDAEDVDVPSPDE 232
           DG  FNA+IH++RPDLV  +R+   S  +NL+ AF VAE +LG+T LL+ EDV+V  PDE
Sbjct: 481 DGLAFNAIIHKHRPDLVQYDRLHKSSAIQNLQNAFTVAEDKLGLTALLEPEDVNVEYPDE 302

Query: 233 KSVITYVSSIYDAFPKVPEG---GEGI-----SATEVDSRWQEYQSRVDSLIPWIRQHTI 284
           KS+ITYV + Y  F K+      G+ I     +A   ++  +EY++    L+ WI Q  +
Sbjct: 301 KSIITYVVTYYHYFSKMKADSVQGKRIGKVIDNAINTENSIEEYETLTSDLLEWIEQTIV 122

Query: 285 LMSDKSFPQNPVELK---ALYNQY 305
           ++ D+ F  +   ++   A +N Y
Sbjct: 121 ILRDRQFANSLTGVQQQLAAFNTY 50
>29446
          Length = 1445

 Score =  103 bits (258), Expect = 2e-21,   Method: Compositional matrix adjust.
 Identities = 60/135 (44%), Positives = 80/135 (59%), Gaps = 8/135 (5%)
 Frame = +3

Query: 28   VQKKTFTKWVNKHLMKVRKHINDLYEDLRDGHNLISLLEVLSGIKLPREKGRMRF--HRL 85
            +QK TFT+W N+HL  V K I DL  D  DG  L++L+EVLSG K      R  F   +L
Sbjct: 999  IQKNTFTRWANEHLRTVNKAIADLESDFSDGLRLVALIEVLSGKKFKHVNKRPNFRTQKL 1178

Query: 86   QNVQIALDFLKQRQ-VKLVNIRNDDITDGNPKLTLGLIWTIILHFQISDIYISGE----- 139
            +NV + L FL+  + +++VNI + DI D   KL LGLIWT+ILH+ IS     GE     
Sbjct: 1179 ENVTLTLKFLEDDEGIRIVNIDSTDIVDKKLKLILGLIWTLILHYSISMPMWEGEEPTPS 1358

Query: 140  SGDMSAKEKLLLWTQ 154
             G  + K++LL W Q
Sbjct: 1359 EGGPTPKQRLLNWIQ 1403
>19147
          Length = 474

 Score =  100 bits (248), Expect = 3e-20,   Method: Compositional matrix adjust.
 Identities = 49/98 (50%), Positives = 66/98 (67%)
 Frame = +1

Query: 94  FLKQRQVKLVNIRNDDITDGNPKLTLGLIWTIILHFQISDIYISGESGDMSAKEKLLLWT 153
           ++  + VKLV+I  ++I DGN K+TLG+IWTIIL F I DI +     +++AKE LLLW 
Sbjct: 49  YIASKGVKLVSIGAEEIVDGNVKMTLGMIWTIILRFAIQDITVE----ELTAKEGLLLWC 216

Query: 154 QKVTAGYTGVKCTNFSSCWSDGKMFNALIHRYRPDLVD 191
           Q+ TA Y  V   NF   + DG  F ALIHR+RP+L+D
Sbjct: 217 QRKTAPYKNVNVQNFHLSFKDGLAFCALIHRHRPELID 330
>17613
          Length = 1108

 Score = 57.0 bits (136), Expect(2) = 1e-13,   Method: Composition-based stats.
 Identities = 44/145 (30%), Positives = 64/145 (44%), Gaps = 12/145 (8%)
 Frame = +1

Query: 80  MRFHRLQNVQIALDF--LKQRQVKLVNIR-------NDDIT---DGNPKLTLGLIWTIIL 127
           MRFH++ NV  ALD+  L++ Q  L   R        DDI    D  P++          
Sbjct: 4   MRFHKIANVNKALDYIDLQRGQTGLHRSRRNC*RQRKDDIRYDLDNYPQVC--------- 156

Query: 128 HFQISDIYISGESGDMSAKEKLLLWTQKVTAGYTGVKCTNFSSCWSDGKMFNALIHRYRP 187
                  +    S     + + ++     TA Y  V   NF   + DG  F ALIHR+RP
Sbjct: 157 -------HPRHHSRRTHCQRRTVIVVPAKTAPYKNVNVQNFHLSFKDGLAFCALIHRHRP 315

Query: 188 DLVDMERVQVQSNRENLEQAFEVAE 212
           +L+D   +   +  ENL  AF++AE
Sbjct: 316 ELIDYHSLSKDNPLENLNTAFDIAE 390

 Score = 41.2 bits (95), Expect(2) = 1e-13,   Method: Composition-based stats.
 Identities = 26/79 (32%), Positives = 39/79 (49%), Gaps = 9/79 (11%)
 Frame = +3

Query: 212 ERLGVTRLLDAED-VDVPSPDEKSVITYVSSIYDAFPKVPEGGEGISA--------TEVD 262
           + L + R+LD ED V+   PDE+SV+ YVSS Y AF    +     +          E +
Sbjct: 390 KHLDIPRMLDPEDMVNSAKPDERSVMAYVSSYYHAFSGAQQAETAANRICKVLKVNQENE 569

Query: 263 SRWQEYQSRVDSLIPWIRQ 281
              +EY+     L+ WIR+
Sbjct: 570 RLMEEYERLASDLLEWIRR 626

 Score = 63.2 bits (152), Expect = 4e-09,   Method: Composition-based stats.
 Identities = 31/58 (53%), Positives = 42/58 (72%)
 Frame = +2

Query: 98  RQVKLVNIRNDDITDGNPKLTLGLIWTIILHFQISDIYISGESGDMSAKEKLLLWTQK 155
           + VKLV+I  ++I DGN K+TLG+IWTIIL F I DI +     +++AKE LLLW Q+
Sbjct: 59  KGVKLVSIGAEEIVDGNVKMTLGMIWTIILRFAIQDITVE----ELTAKEGLLLWCQR 220
>34417
          Length = 1096

 Score = 74.3 bits (181), Expect = 2e-12,   Method: Composition-based stats.
 Identities = 37/78 (47%), Positives = 50/78 (64%), Gaps = 2/78 (2%)
 Frame = +2

Query: 168 FSSCWSDGKMFNALIHRYRPDLVDMERVQVQSNRENLEQAFEVAERLG-VTRLLDAED-V 225
            SSCW++G  F ALIH + PD  D  ++Q Q+ R N E AF+ AE+L  ++ LLD ED +
Sbjct: 35  LSSCWNNGLAFCALIHHFYPDAFDYSQLQPQNRRYNFELAFDTAEKLADISPLLDVEDMI 214

Query: 226 DVPSPDEKSVITYVSSIY 243
            + +PD K V TYV S Y
Sbjct: 215 KMKNPDWKCVFTYVQSFY 268
>09711
          Length = 3041

 Score = 64.7 bits (156), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 58/225 (25%), Positives = 103/225 (45%), Gaps = 21/225 (9%)
 Frame = +1

Query: 22   MDERDRVQKKTFTKWVNKHLMKVRKHINDLYEDLRDGHNLISLLEVL-------SGIKLP 74
            M E  R ++KT+  W+N   + V   ++ LY DL DG  +  L + +       S +K  
Sbjct: 832  MKEESR-EEKTYRNWMNS--LGVSPFVHHLYSDLYDGLIIFQLYDYIQPGLVDWSKVKKK 1002

Query: 75   REKGRMRFHRLQNVQIALDF---LKQRQVKLVNIRNDDITDGNPKLTLGLIWTIILHFQI 131
              K + RF R++N   A++    +K  +VKLV I   DI DGNP LTLGL+W ++  + +
Sbjct: 1003 FNKLKARFERIENCNYAVELGPQVKLVKVKLVGIAGQDILDGNPVLTLGLVWQLMRAYTL 1182

Query: 132  SDIYISGESGDMSAKEKLLLWTQ-KV-----TAGYTGVKCTNFSSCWSDGKMFNALIHRY 185
            + +    E+    +  +++ W   K+      +G+   K        +DG +   +I   
Sbjct: 1183 AILSKITENNKPISDNEIITWVNSKIKKDDRISGFQDRKL-------NDGVIVARVIEAI 1341

Query: 186  RPDLVDMERVQV-----QSNRENLEQAFEVAERLGVTRLLDAEDV 225
            +P +V+ + +       Q    N   A  +A ++G       ED+
Sbjct: 1342 KPGIVNWDNIDCSARDYQDRLTNARYAIGLARKIGAGVYALPEDI 1476

 Score = 52.4 bits (124), Expect = 7e-06,   Method: Compositional matrix adjust.
 Identities = 56/252 (22%), Positives = 109/252 (43%), Gaps = 31/252 (12%)
 Frame = +1

Query: 29  QKKTFTKWVNKHLMKVR--KHI-------NDLYEDLRDGHNLISLLE--VLSGI--KLPR 75
           ++K F +W+N+HL      KH+         L+  + DG  L  L+   V + I  +   
Sbjct: 52  EQKAFAEWINRHLSDXPDCKHLLPLDADGTQLFGQMADGVLLCKLINHSVSNTIDERTIN 231

Query: 76  EKGRMRFHRLQNVQIALDFLKQRQVKLVNIRNDDITDGNPKLTLGLIWTIILHFQISDIY 135
           ++    + R +N+ +A++         VNI  +D+  G P L LGL+W II    +SDI 
Sbjct: 232 KQNLSLYRRHENLTLAVNSAGAIGCTTVNIGPEDLAAGRPHLVLGLLWQIIRIGLLSDIN 411

Query: 136 ISGESG---------------DMSAKEKLLLWTQ-KVTAGYTGVKCTNFSSCWSDGKMFN 179
           ++   G                +S ++ LL W    +       +  NF     D + + 
Sbjct: 412 LAHHPGLVNLLLDGETIEDLIRLSPEQILLRWVNYHLNRAGCDRQIXNFGEDIKDSEAYT 591

Query: 180 ALIHRYRPDL--VDMERVQVQSNRENLEQAFEVAERLGVTRLLDAEDVDVPSPDEKSVIT 237
            L+ +  P    V +  + V    +  E   + A+++G    + A   DV S ++K  + 
Sbjct: 592 HLLKQISPPSAGVTLSPLSVGDVHQRAECMLQEADKIGCRSFVGAS--DVVSGNQKLNLA 765

Query: 238 YVSSIYDAFPKV 249
           +V+++++ +P +
Sbjct: 766 FVANLFNNYPAL 801
>05733
          Length = 1021

 Score = 63.5 bits (153), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 34/102 (33%), Positives = 57/102 (55%), Gaps = 4/102 (3%)
 Frame = +2

Query: 149 LLLWTQKV--TAGYTGVKCTNFSSCWSDGKMFNALIHRYRPDLVDMERVQVQSNRENLEQ 206
           LL W Q+V     Y GV   +F+S W  G  F ALIH +RP L+    +      +N + 
Sbjct: 470 LLRWCQRVLNXGTYRGVHIIDFTSSWRSGLAFCALIHAFRPHLISPASLMECETVKNNQL 649

Query: 207 AFEVAER-LGVTRLLDAEDVDVPS-PDEKSVITYVSSIYDAF 246
           AF+VA++ LG+  ++  ED+   + PD+ +++ Y+S  ++ F
Sbjct: 650 AFDVAQKELGIAPVMRGEDMAACAVPDKLTMVAYLSQFHELF 775
>19912
          Length = 865

 Score = 54.7 bits (130), Expect = 1e-06,   Method: Composition-based stats.
 Identities = 26/70 (37%), Positives = 39/70 (55%)
 Frame = +2

Query: 7052 KYMRWMNHKKSRVMDFFRRIDKDQDGKITRQEFIDGILASKFPTTKLEMTAVADIFDRDG 7111
            K M +++    R++DFF + DK+    ITR +F  G+  +  P    E+  + D  DRDG
Sbjct: 638  KLMAYIDSNNLRLVDFFNKFDKEGTMSITRDQFRQGLTEASIPLAGDEVDFLLDELDRDG 817

Query: 7112 DGYIDYYEFV 7121
            DG I+Y E V
Sbjct: 818  DGEINYSELV 847
>23752
          Length = 853

 Score = 53.9 bits (128), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 38/126 (30%), Positives = 62/126 (49%), Gaps = 3/126 (2%)
 Frame = -2

Query: 712 AVQSQLQWMKQLCLCVEQHVKENAAYFQFFSDARDLESFLRNLQDSIKRKYTCDRSTSLS 771
           AV+S  QWM Q+  C E H++  AAY +FF +  + E ++ N    I   +  DR+    
Sbjct: 366 AVRSNWQWMSQVMQCAEVHLRNAAAYHEFFHEVEEAEYWMENTLSRIHMSF--DRNKLQG 193

Query: 772 RLEDL--LQDSMDEK-EQLIQSKSSVASLVGRSKTIVQLKPRNPDHVLKSTLSVKAICDY 828
              D+  +QD + E     +Q ++ +  L  R+KT+V +  R     LK    V A+ D+
Sbjct: 192 NRTDVVAIQDEIKEVLAGFLQWQTKIDYLFDRAKTVVPVPQRTT--ALKEERPVIALTDF 19

Query: 829 RQIEIT 834
              +IT
Sbjct: 18  SNSQIT 1
>32088
          Length = 1928

 Score = 52.8 bits (125), Expect = 5e-06,   Method: Composition-based stats.
 Identities = 38/126 (30%), Positives = 62/126 (49%), Gaps = 13/126 (10%)
 Frame = +1

Query: 29   QKKTFTKWVN---------KHLMKVRKHINDLYEDLRDGHNLISLL-EVLSGIKLPREKG 78
            ++K F  W+N         KHLM+V +  +DL++ + DG  L  L+   +S     R   
Sbjct: 1264 EQKAFAAWINRHLKDDPDCKHLMEVNEEGDDLFKKVGDGILLCKLINHSVSNTIDERAIN 1443

Query: 79   RMR---FHRLQNVQIALDFLKQRQVKLVNIRNDDITDGNPKLTLGLIWTIILHFQISDIY 135
            +     +HR +N+ +A++         VNI  +D+  G P L LGL+W II    +SDI 
Sbjct: 1444 KSNLNVYHRHENLTLAVNSAGSIGCTTVNIGPEDLAAGRPHLVLGLLWQIIRIGLLSDIN 1623

Query: 136  ISGESG 141
            ++   G
Sbjct: 1624 LAHHPG 1641
>09100
          Length = 930

 Score = 48.1 bits (113), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 35/110 (31%), Positives = 54/110 (49%), Gaps = 8/110 (7%)
 Frame = +1

Query: 29  QKKTFTKWVNKHLMK-VRKH-INDLYEDLRDGHNLISLLEVLS-----GIK-LPREKGRM 80
           Q   +  W+N  L K    H I DL  D+RDG     ++ ++S     GI+ +P     M
Sbjct: 463 QLSAYMAWINSQLKKKPGAHLIEDLRHDMRDGVVFADVIHIVSKQQIPGIQNVPTTLDEM 642

Query: 81  RFHRLQNVQIALDFLKQRQVKLVNIRNDDITDGNPKLTLGLIWTIILHFQ 130
           R    QNV   L F+ Q ++K+  I + DI +GN K  + LI  +  H++
Sbjct: 643 R----QNVDRVLHFMTQNRIKMHRISSRDIVEGNLKAVMRLILALAAHYK 780
>18556
          Length = 799

 Score = 43.9 bits (102), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 34/111 (30%), Positives = 54/111 (48%), Gaps = 4/111 (3%)
 Frame = +2

Query: 140 SGD-MSAKEKLLLWTQKVTAGYT-GVKCTNFSSCWSDGKMFNALIHRYRPDLVDMERVQV 197
           SGD +     LL W     A Y    +    S  + +G++  ALI R+RPDL+D    + 
Sbjct: 17  SGDTLPQGASLLRWISVQLAAYQFTAELKEPSDVFRNGRVLCALISRFRPDLIDYAATKD 196

Query: 198 QSNRENLEQAFEVAER-LGVTRLLDA-EDVDVPSPDEKSVITYVSSIYDAF 246
            S  E  E AF V ER L + R++ A + +D+   + +  + Y+  I + F
Sbjct: 197 MSPLECNELAFAVLERELHIDRIMSAKQSLDLNDVESRVWLNYMDQICELF 349
>04951
          Length = 2852

 Score = 42.7 bits (99), Expect = 0.006,   Method: Composition-based stats.
 Identities = 43/191 (22%), Positives = 79/191 (41%), Gaps = 9/191 (4%)
 Frame = +1

Query: 84  RLQNVQIALDFLKQRQV---KLVNIRNDDITDGNPKLTLGLIWTIILHFQISDIYISGES 140
           +++N + A+    Q +V   KLV I   DI DGNP LTLGL+W ++  + ++ +    E 
Sbjct: 4   KIENCEYAVQLGPQMKVCKMKLVGIGGKDIHDGNPVLTLGLVWQLMRAYTLAILSKLTED 183

Query: 141 GDMSAKEKLLLWTQKVTAGYTGVKCTNFSSCWSDGKMFNALIHRYRPDLVDMERVQVQSN 200
                  +++ W          +      S  +DG +   +I   +P +V+ E +   ++
Sbjct: 184 KKPIQDSEIVDWVNSKVKKDERIGSFQ-DSKLNDGVIVAKVIESIKPGIVNWENINPNAS 360

Query: 201 R-----ENLEQAFEVAERLGVTRLLDAEDVDVPSPDEKSVITYVSSIYD-AFPKVPEGGE 254
                  N   A  +A ++G       ED+    P     +     + D +  K  +G  
Sbjct: 361 EPDDRLANARYAIGLARKIGAGVYALPEDIVEVKPKMLLTVFACLMMRDLSAHKATQGVR 540

Query: 255 GISATEVDSRW 265
           G +A   +S W
Sbjct: 541 GPTAANKNSCW 573
>18202
          Length = 424

 Score = 40.8 bits (94), Expect = 0.022,   Method: Composition-based stats.
 Identities = 35/134 (26%), Positives = 63/134 (47%), Gaps = 10/134 (7%)
 Frame = -1

Query: 31  KTFTKWVNKHLMKVRKHINDLYEDLRDGHNLISLLEVLS-------GIKLPREKGRMRFH 83
           + +  W N  L +V   + ++   +++G  L  L++VL+        ++   + G+  F 
Sbjct: 385 QVYLSWANSVLCEVNSSVENV-SSIQEGRVLCELIDVLAPEAGLLDKVQASGKSGQRAF- 212

Query: 84  RLQNVQIALDFLKQRQVKLVNIRNDDITDGNPKLTLGLIWTIILHFQISDIYISGESGDM 143
               +  ALD +K   +K+V     DI DG+ K  L ++W +IL++ I   +I   S   
Sbjct: 211 ----IYAALDHMKNHGIKIV-FSTQDIMDGDIKSLLDVMWLLILNYGIH--FIGNNSFQR 53

Query: 144 S---AKEKLLLWTQ 154
           S    K+ LL W Q
Sbjct: 52  SVGAGKKNLLDWCQ 11
>32371
          Length = 625

 Score = 27.3 bits (59), Expect(3) = 0.038,   Method: Composition-based stats.
 Identities = 12/28 (42%), Positives = 17/28 (60%), Gaps = 1/28 (3%)
 Frame = -3

Query: 234 SVITYVSSIYDAFPKVPE-GGEGISATE 260
           SVITYVS  Y+    +P+ GG G+   +
Sbjct: 401 SVITYVSQYYNKLSTLPQLGGPGVQGND 318

 Score = 25.4 bits (54), Expect(3) = 0.038,   Method: Compositional matrix adjust.
 Identities = 17/48 (35%), Positives = 28/48 (58%), Gaps = 2/48 (4%)
 Frame = -2

Query: 187 PDLVDMERVQVQSNRENLEQAFEVAER-LGVTRLLDAED-VDVPSPDE 232
           PDL+D + +  ++   N   AF VAE+ L +   L+A D V + +PD+
Sbjct: 549 PDLIDYDSLSKENVLYNNNLAFTVAEQELDIPAFLEAADMVALRTPDK 406

 Score = 24.6 bits (52), Expect(3) = 0.038,   Method: Composition-based stats.
 Identities = 8/15 (53%), Positives = 11/15 (73%)
 Frame = -1

Query: 172 WSDGKMFNALIHRYR 186
           W +G  F A+IHR+R
Sbjct: 595 WRNGLAFCAIIHRFR 551
>26019
          Length = 1561

 Score = 37.0 bits (84), Expect = 0.30,   Method: Composition-based stats.
 Identities = 20/62 (32%), Positives = 33/62 (53%)
 Frame = +2

Query: 7063 RVMDFFRRIDKDQDGKITRQEFIDGILASKFPTTKLEMTAVADIFDRDGDGYIDYYEFVA 7122
            R+   FR++D D  G ++  EF+      + P  +     V DIFD DG+G +D+ EF+ 
Sbjct: 101  RLGKRFRKLDLDNSGSLSIDEFMSLPELQQNPLVQ----RVIDIFDTDGNGEVDFKEFIE 268

Query: 7123 AL 7124
             +
Sbjct: 269  GI 274
>17484
          Length = 471

 Score = 36.2 bits (82), Expect = 0.46,   Method: Composition-based stats.
 Identities = 18/67 (26%), Positives = 34/67 (50%)
 Frame = -3

Query: 7054 MRWMNHKKSRVMDFFRRIDKDQDGKITRQEFIDGILASKFPTTKLEMTAVADIFDRDGDG 7113
            M+  + K   + D FR  D++ DG I+  E    +       +  ++ ++    D+DGDG
Sbjct: 295  MKGGSEKDKEMRDAFRAFDQNGDGVISISELRQAMAKMGQKLSDADVESIIRDVDKDGDG 116

Query: 7114 YIDYYEF 7120
            +++Y EF
Sbjct: 115  FVNYEEF 95
>07678
          Length = 958

 Score = 35.0 bits (79), Expect = 1.2,   Method: Composition-based stats.
 Identities = 21/68 (30%), Positives = 35/68 (51%), Gaps = 3/68 (4%)
 Frame = +1

Query: 7068 FRRIDKDQDGKITRQEFIDGILASKFPTTKLEMTAVADIF---DRDGDGYIDYYEFVAAL 7124
            F+ +D D +  +  +EF  GI  ++F  T+ E   + ++F   D+D  G ID+ EF+  L
Sbjct: 337  FKIMDDDGNRSLDFKEFKKGI--TEFGLTQFEGDVIQEMFTCFDKDZSGTIDFDEFLVKL 510

Query: 7125 HPNKDAYR 7132
             P     R
Sbjct: 511  RPPMSQMR 534
>35978
          Length = 711

 Score = 34.7 bits (78), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 33/127 (25%), Positives = 67/127 (52%), Gaps = 9/127 (7%)
 Frame = +1

Query: 1128 KLSQEEAVPADLSALESHRTT--------LQHWLSDVKDKN-SVFSVLDEEITKAKKVAE 1178
            K SQE++V     A E  R          L     DV+D N ++F+ ++E+  + +K+ E
Sbjct: 157  KESQEDSVETYEQAFEQIREMTGEDDLDLLVTRFIDVEDTNFALFNYVNEQNNEIEKLNE 336

Query: 1179 QLRHPASEPNLDLERYQEKGSQLQERWHRVIAQLETRQSEVESIQEVLRDYRACHGTLIK 1238
            Q+    +    D+E+++E+G +L+++   ++ QLE +Q+   +++E   DY   H  + K
Sbjct: 337  QIEGIKN----DIEKFKEQGIELEDQRQVILKQLEVKQT--SALKEA-DDYEQKHKEVAK 495

Query: 1239 WIEETTA 1245
             +++  A
Sbjct: 496  ILDQLKA 516
>17977
          Length = 445

 Score = 34.3 bits (77), Expect = 2.0,   Method: Composition-based stats.
 Identities = 22/76 (28%), Positives = 33/76 (43%)
 Frame = +3

Query: 7050 RKKYMRWMNHKKSRVMDFFRRIDKDQDGKITRQEFIDGILASKFPTTKLEMTAVADIFDR 7109
            R++  ++  H    ++  FR  DKD  GKI   +  +       P     +  V D  D 
Sbjct: 183  RQQLKKFNYHSFPDLIRAFRFYDKDGKGKIDIDDLREACRKFDVPIDVWLLEQVFDYCDE 362

Query: 7110 DGDGYIDYYEFVAALH 7125
            + DG IDY EF   L+
Sbjct: 363  NRDGQIDYLEFANFLN 410
>26849
          Length = 649

 Score = 33.9 bits (76), Expect = 2.6,   Method: Composition-based stats.
 Identities = 18/54 (33%), Positives = 29/54 (53%)
 Frame = +2

Query: 7068 FRRIDKDQDGKITRQEFIDGILASKFPTTKLEMTAVADIFDRDGDGYIDYYEFV 7121
            FR +DKD    ++ +EF  GIL       + ++  +   FD DG+G I+  EF+
Sbjct: 185  FRVMDKDGSKVLSLEEFKKGILDMHIDINEADIEDMFYRFDNDGNGTINMTEFL 346
>22444
          Length = 554

 Score = 33.1 bits (74), Expect = 4.4,   Method: Compositional matrix adjust.
 Identities = 12/38 (31%), Positives = 25/38 (65%)
 Frame = +1

Query: 4431 PKIQKVKEALAGLLKTYPNSQEAENWKKMQEDLNSRWE 4468
            P IQ++ + ++ L +TYP++  + + + +   L+SRWE
Sbjct: 427  PSIQRMAQQISALSQTYPHTTPSPSRRLLPPTLSSRWE 540
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|13384724|ref|NP_079636.1| transmembrane emp24 domain
containing 3 [Mus musculus]
         (221 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

38580                                                                 197   4e-51
19964                                                                  79   1e-15
>38580
          Length = 727

 Score =  197 bits (500), Expect = 4e-51,   Method: Compositional matrix adjust.
 Identities = 90/152 (59%), Positives = 117/152 (76%)
 Frame = +1

Query: 34  TFELPDNAKQCFHEEVEQGVKFSLDYQVITGGHYDVDCYVEDPRGNVIYRETKKQYDSFT 93
           TFELPDN K CFHE V++GVK +++YQV+ GG+YDVD  +  P G V+Y+E KKQYDSFT
Sbjct: 154 TFELPDNEKMCFHELVDKGVKATIEYQVVMGGNYDVDMELTAPTGQVLYKEVKKQYDSFT 333

Query: 94  YKTEAKGVYRFCFSNEFSTFSHKTVYFDFQVGDEPPILPDMGNRVTALTQMESACVTIHE 153
           +  + KG++ FCFSNEFSTF+HK VYFD QVGD+ P+    G+ VTA+T +E++ V + E
Sbjct: 334 WTADVKGIHAFCFSNEFSTFTHKVVYFDLQVGDDKPVGDTDGDHVTAMTSIENSAVNLFE 513

Query: 154 ALKTVIDSQTHYRLREAQDRARAEDLNSRVSY 185
            LK V+D QTH+RLREAQ RA AED+N RV +
Sbjct: 514 ELKRVLDLQTHFRLREAQGRAFAEDVNERVLF 609
>19964
          Length = 901

 Score = 79.3 bits (194), Expect = 1e-15,   Method: Compositional matrix adjust.
 Identities = 42/146 (28%), Positives = 72/146 (49%)
 Frame = +2

Query: 47  EEVEQGVKFSLDYQVITGGHYDVDCYVEDPRGNVIYRETKKQYDSFTYKTEAKGVYRFCF 106
           ++V  G K SL ++V  GG  D+D  +  P   VI++  ++    +T+     G+Y++CF
Sbjct: 5   DKVSSGTKMSLMFEVAEGGFLDIDVKIYGPDNKVIHQGERESNGKYTFAAHMDGIYKYCF 184

Query: 107 SNEFSTFSHKTVYFDFQVGDEPPILPDMGNRVTALTQMESACVTIHEALKTVIDSQTHYR 166
           SN+ ST + K V F   VG++P       +   +  ++E     +  AL      Q +  
Sbjct: 185 SNQMSTMTPKVVMFSMDVGEKPKDQDGDKDSDASHGKLEEMVNQLSTALTGAKHEQEYME 364

Query: 167 LREAQDRARAEDLNSRVSYWSVGETI 192
           +RE   RA  ++ NSRV  W+  E +
Sbjct: 365 VRERIHRAINDNTNSRVVLWAFFEAL 442
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|22122717|ref|NP_666288.1| CCR4-NOT transcription
complex, subunit 3 [Mus musculus]
         (751 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

06782                                                                 199   4e-51
06585                                                                  78   1e-14
>06782
          Length = 1144

 Score =  199 bits (506), Expect = 4e-51,   Method: Compositional matrix adjust.
 Identities = 93/167 (55%), Positives = 125/167 (74%)
 Frame = -3

Query: 71   IKDKRQLIENRKLIETQMERFKVVERETKTKAYSKEGLGLAQKVDPAQKEKEEVGQWLTN 130
            +KDK+ L+E+RKLIETQMERFKV+ERETKTKAYSK+GLG A K+DP  KEK E+  WL+ 
Sbjct: 1070 VKDKQPLVESRKLIETQMERFKVLERETKTKAYSKDGLGAAAKLDPQTKEKSEITSWLST 891

Query: 131  TIDTLNMQVDQFESEVESLSVQTRXXXXXXXXXXRIEGLKRHIEKHRYHVRMLETILRML 190
             ID L +QVDQ E E+ES+   ++          R + LK   ++H++H++ LE  +R +
Sbjct: 890  QIDALQLQVDQLECELESMECTSKRKKMDKESGPRSDELKLRRDRHKFHIKHLEMAMRAV 711

Query: 191  DNDSILVDAIRKIKDDVEYYVDSSQDPDFEENEFLYDDLDLEDIPQA 237
            DND++ VD I+ I+DDV+YYVD +Q+PDFEENEFLY DLDLEDI ++
Sbjct: 710  DNDALPVDQIKNIRDDVDYYVDFNQEPDFEENEFLYQDLDLEDIGES 570
>06585
          Length = 761

 Score = 77.8 bits (190), Expect = 1e-14,   Method: Compositional matrix adjust.
 Identities = 33/45 (73%), Positives = 37/45 (82%)
 Frame = +3

Query: 595 LGVCPLGPVSLTKEQLYQQAMEEAAWHHMPHPSDSERIRQYLPRN 639
           LG+ PLGPV  TKE  YQ AM EAA+HH+PHPSDSER+R YLPRN
Sbjct: 615 LGMAPLGPVPPTKENSYQLAMTEAAYHHLPHPSDSERLRHYLPRN 749
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|82889417|ref|XP_130859.7| PREDICTED: progesterone
receptor membrane component 2 isoform 1 [Mus musculus]
         (217 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

05429                                                                 196   5e-51
31402                                                                  35   0.030
>05429
          Length = 830

 Score =  196 bits (498), Expect = 5e-51,   Method: Compositional matrix adjust.
 Identities = 92/122 (75%), Positives = 110/122 (90%), Gaps = 1/122 (0%)
 Frame = +3

Query: 89  LPRMKKRDFSLEQLRQYDG-ARTPRILLAVNGKVFDVTKGSKFYGPAGPYGIFAGRDASR 147
           LP +KK+DF+LEQLR+YDG ++  RIL+AVNGKVFDVTKG +FYGP GPYG+F+GRDASR
Sbjct: 144 LPPLKKQDFTLEQLREYDGKSKNGRILIAVNGKVFDVTKGKRFYGPGGPYGLFSGRDASR 323

Query: 148 GLATFCLDKDALRDEYDDLSDLNAVQMESVREWEMQFKEKYDYVGRLLKPGEEPSEYTDE 207
            LATF L +D+LRDEYDDLSDLN++QMESVREWEMQF EKY YVG+LLKPGE+P++YTD 
Sbjct: 324 ALATFSLSEDSLRDEYDDLSDLNSMQMESVREWEMQFTEKYVYVGKLLKPGEQPADYTDT 503

Query: 208 ED 209
           ED
Sbjct: 504 ED 509
>31402
          Length = 1272

 Score = 34.7 bits (78), Expect = 0.030,   Method: Compositional matrix adjust.
 Identities = 19/55 (34%), Positives = 28/55 (50%)
 Frame = +2

Query: 141 AGRDASRGLATFCLDKDALRDEYDDLSDLNAVQMESVREWEMQFKEKYDYVGRLL 195
           AGRD SR   T    +  L D   D+S   A +   + EW+  +K  Y YVG+++
Sbjct: 2   AGRDGSRAFVTGDFTEKGLTD---DVSGFTASEALGLEEWDSFYKRDYTYVGKVV 157
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|19882225|ref|NP_080212.1| arginyl-tRNA synthetase
[Mus musculus]
         (660 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

34849                                                                 119   9e-51
01992                                                                  30   4.4  
>34849
          Length = 545

 Score =  119 bits (297), Expect(2) = 9e-51,   Method: Compositional matrix adjust.
 Identities = 58/78 (74%), Positives = 67/78 (85%)
 Frame = +1

Query: 449 KKKFKTRSGETVRLMDLLEEGLKRSLDKLKEKERDKVLTEEELKAAQTSVAYGCIKYADL 508
           +K+FKTRSGETVRL+DLL+EG+KRS  KL EKERDKVL+ EELK A+ SVAYGCIKYADL
Sbjct: 205 QKEFKTRSGETVRLVDLLDEGVKRSEAKLIEKERDKVLSAEELKKAKESVAYGCIKYADL 384

Query: 509 SHNRLNDYIFSFDKMLDD 526
           +HNR  DY+FSFDK   D
Sbjct: 385 AHNRTKDYVFSFDKXXGD 438

 Score =  100 bits (250), Expect(2) = 9e-51,   Method: Composition-based stats.
 Identities = 45/70 (64%), Positives = 54/70 (77%)
 Frame = +2

Query: 381 GYTYDTSDLAAIKQRLFEEKANKIIYVVDNGQAIHFQTIFAAAQMIGWYDPKVTLVTHVG 440
           GYTYDTSD+A I+QRL EE+ + +IYVVD+GQ  H  TI+ AA+ +GW DP    V HVG
Sbjct: 2   GYTYDTSDMACIRQRLQEERGDWLIYVVDSGQGTHLTTIYEAAKQLGWIDPSKHRVEHVG 181

Query: 441 FGVVLGEDKK 450
           FGVVLGEDKK
Sbjct: 182 FGVVLGEDKK 211
>01992
          Length = 1463

 Score = 29.6 bits (65), Expect = 4.4,   Method: Compositional matrix adjust.
 Identities = 14/41 (34%), Positives = 24/41 (58%)
 Frame = -1

Query: 187  VLGDKEKVIVDFSSPNIAKEMHVVHLRSTIIGESMSRLFEF 227
            + GD++  + D  S NI+  +HV+H     IG S+S ++ F
Sbjct: 1343 IAGDRKVYLPDSVSYNISLSIHVLHELFNCIGCSISYIYSF 1221
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|30424609|ref|NP_776122.1| YTH domain family 1 [Mus
musculus]
         (559 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

37635                                                                 197   9e-51
26363                                                                  91   9e-19
11885                                                                  38   7e-06
12584                                                                  28   8.0  
18162                                                                  28   8.4  
>37635
          Length = 2610

 Score =  197 bits (501), Expect = 9e-51,   Method: Compositional matrix adjust.
 Identities = 86/109 (78%), Positives = 101/109 (92%)
 Frame = +3

Query: 431 KGPVYLLFSVNGSGHFCGVAEMKSPVDYGTSAGVWSQDKWKGKFDVKWIFVKDVPNNQLR 490
           KGP+YLL+SVNGSGHFCG+AEM SP+DY  +A VW+QDKWKG+F VKW++VKDVPN+QLR
Sbjct: 12  KGPIYLLYSVNGSGHFCGIAEMLSPIDYNKNASVWAQDKWKGQFTVKWVYVKDVPNSQLR 191

Query: 491 HIRLENNDNKPVTNSRDTQEVPLEKAKQVLKIIASYKHTTSIFDDFSHY 539
           HIRLENN+NKPVTNSRDTQEVP EK KQV+KI+ +YKHTTSIFDDF+HY
Sbjct: 192 HIRLENNENKPVTNSRDTQEVPPEKGKQVMKILHNYKHTTSIFDDFTHY 338
>26363
          Length = 442

 Score = 91.3 bits (225), Expect = 9e-19,   Method: Composition-based stats.
 Identities = 51/108 (47%), Positives = 62/108 (57%)
 Frame = -2

Query: 432 GPVYLLFSVNGSGHFCGVAEMKSPVDYGTSAGVWSQDKWKGKFDVKWIFVKDVPNNQLRH 491
            PVYL FS  GS HF GVAEM S VDY    G        G FDVKW +VKDVP+ +  H
Sbjct: 429 APVYLFFSCVGSRHFHGVAEMTSAVDYDDRFG---NGFLHGGFDVKWHYVKDVPSMRFSH 259

Query: 492 IRLENNDNKPVTNSRDTQEVPLEKAKQVLKIIASYKHTTSIFDDFSHY 539
           I++   DNKP+  SR+  E+ L +  Q LK+   + HTTSI  D   Y
Sbjct: 258 IKV-GEDNKPMFRSRNGDELTLSRGLQALKVFHDFNHTTSILMDTDFY 118
>11885
          Length = 479

 Score = 37.7 bits (86), Expect(2) = 7e-06,   Method: Compositional matrix adjust.
 Identities = 28/89 (31%), Positives = 43/89 (48%), Gaps = 11/89 (12%)
 Frame = +3

Query: 434 VYLLFSVNGSGHFCGVAEMKS-------PVDY----GTSAGVWSQDKWKGKFDVKWIFVK 482
           +Y  FSV  SG F G A + +       P+ +    G +A V S       F + WI  +
Sbjct: 213 LYSSFSVKESGKFQGYARLAAESTKDHPPIRWVLPPGMNARVLS-----AVFKLDWIDRR 377

Query: 483 DVPNNQLRHIRLENNDNKPVTNSRDTQEV 511
           ++P ++  H+    N+NKPV   RD QE+
Sbjct: 378 ELPFSKTNHLHNPWNENKPVKIGRDGQEI 464

 Score = 30.0 bits (66), Expect(2) = 7e-06,   Method: Composition-based stats.
 Identities = 20/83 (24%), Positives = 36/83 (43%)
 Frame = +2

Query: 360 PSVESHPVLEKLKAAHSYNPKEFDWNLKSGRVFIIKSYSEDDIHRSIKYSIWCSTEHGNK 419
           P VE     + L  +H     +  +  +  R F+IKS + +++  +    +W +      
Sbjct: 8   PPVEEEKEDQALTESHL---AKLKYLFRGARFFLIKSNNYENVALARAKGVWSTPPQNES 178

Query: 420 RLDGAFRSMSSKGPVYLLFSVNG 442
           RL+ AFR   +   V L+F   G
Sbjct: 179 RLNQAFRECEN---VILIFLCQG 238
>12584
          Length = 723

 Score = 28.5 bits (62), Expect = 8.0,   Method: Compositional matrix adjust.
 Identities = 12/34 (35%), Positives = 20/34 (58%)
 Frame = -1

Query: 392 FIIKSYSEDDIHRSIKYSIWCSTEHGNKRLDGAF 425
           F+IK+ S  ++   +  S+WC T H ++R   AF
Sbjct: 699 FLIKASSNTNLTSCLIISLWCHTYH*SQRTKRAF 598
>18162
          Length = 476

 Score = 28.5 bits (62), Expect = 8.4,   Method: Composition-based stats.
 Identities = 16/43 (37%), Positives = 20/43 (46%)
 Frame = +3

Query: 226 MPVSKPTSWAAIASKPAKPQPKMKTKSGPIVGGALPPPPIKHN 268
           +PVS   +W   AS  A P P    +S P    AL PP   H+
Sbjct: 261 LPVSSCPTWGRAASTRAGPNP*PALRSAPATRPALGPPQNHHH 389
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|160298209|ref|NP_034454.2| glutamate oxaloacetate
transaminase 1, soluble [Mus musculus]
         (413 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

29384                                                                 196   1e-50
29203                                                                 149   2e-36
33824                                                                  98   5e-21
38224                                                                  36   0.001
>29384
          Length = 672

 Score =  196 bits (499), Expect = 1e-50,   Method: Compositional matrix adjust.
 Identities = 86/182 (47%), Positives = 126/182 (69%)
 Frame = -1

Query: 144 HNAVFSAAGFKDIRPYCYWDAEKRGLDLQGFLNDLENAPEFSIFVLHACAHNPTGTDPTP 203
           H  +F  AG  +++ Y Y+D    G D  G ++D+ N P+ S+ VLHACAHNPTG DP P
Sbjct: 597 HTPIFKHAGL-NVKSYRYYDPSTCGFDFAGAMDDISNMPKGSVIVLHACAHNPTGVDPKP 421

Query: 204 EQWKQIAAVMQRRFLFPFFDSAYQGFASGDLEKDAWAIRYFVSEGFELFCAQSFSKNFGL 263
           EQW +++  +++R +FPFFD AYQGFASGD+++DA+A+R FV +G ++  +QSF+KN GL
Sbjct: 420 EQWCEMSQELKKRDIFPFFDMAYQGFASGDIDRDAFAVRQFVKDGHQVALSQSFAKNMGL 241

Query: 264 YNERVGNLTVVGKESDSVLRVLSQMEKIVRITWSNPPAQGARIVAATLSDPELFKEWKGN 323
           Y ERVG  T++ +  +   RV+SQ++ ++R  +SNPP  GARI    L+ PEL K+W   
Sbjct: 240 YGERVGAFTIICESKEEADRVMSQIKILIRPMYSNPPIHGARIAGCILNTPELRKQWLTE 61

Query: 324 VK 325
           V+
Sbjct: 60  VE 55
>29203
          Length = 839

 Score =  149 bits (376), Expect = 2e-36,   Method: Compositional matrix adjust.
 Identities = 68/125 (54%), Positives = 89/125 (71%)
 Frame = +3

Query: 287 QMEKIVRITWSNPPAQGARIVAATLSDPELFKEWKGNVKTMADRILTMRSELRARLEALK 346
           QME I R  WSNP   GARIV+  L++P L ++W G VK MADRI  MR  +  +L   +
Sbjct: 3   QMEIISRTMWSNPSHHGARIVSMVLNNPALCEQWSGEVKQMADRISGMRQMMVNKLRKKE 182

Query: 347 TPGTWSHITEQIGMFSFTGLNPKQVEYLVNEKHIYLLPSGRINMCGLTTKNLDYVATSIH 406
            PGTW+HI  QIGMFSFTGL P QV+ +V + H+Y+L +GRI+M GLTTKN+DYV  +I 
Sbjct: 183 MPGTWNHILRQIGMFSFTGLTPDQVKIMVEDHHVYMLSNGRISMAGLTTKNVDYVVDAIC 362

Query: 407 EAVTK 411
           +A+T+
Sbjct: 363 DAITR 377
>33824
          Length = 675

 Score = 98.2 bits (243), Expect = 5e-21,   Method: Compositional matrix adjust.
 Identities = 50/113 (44%), Positives = 71/113 (62%)
 Frame = -2

Query: 295 TWSNPPAQGARIVAATLSDPELFKEWKGNVKTMADRILTMRSELRARLEALKTPGTWSHI 354
           +WS      ++    TL  PE  K+W   VK MADRI++MR++L+  L    +   W HI
Sbjct: 566 SWSTHCRMYSQTHPGTL--PE--KQWLTEVKGMADRIISMRTQLKDNLAKEGSSRNWDHI 399

Query: 355 TEQIGMFSFTGLNPKQVEYLVNEKHIYLLPSGRINMCGLTTKNLDYVATSIHE 407
           T+QIGMF FTGL P QVE L  +  +YL   GRI++ GL++KN+ Y+A ++HE
Sbjct: 398 TDQIGMFCFTGLGPDQVERLTKDFSVYLTKDGRISVAGLSSKNVGYLAKAMHE 240

 Score = 37.4 bits (85), Expect = 0.011,   Method: Compositional matrix adjust.
 Identities = 15/40 (37%), Positives = 25/40 (62%)
 Frame = -3

Query: 272 TVVGKESDSVLRVLSQMEKIVRITWSNPPAQGARIVAATL 311
           T++ +  +   RV+SQ++ ++R  +SNPP  GARI    L
Sbjct: 655 TIICESKEEADRVMSQIKILIRPMYSNPPIHGARIAGCIL 536
>38224
          Length = 618

 Score = 35.8 bits (81), Expect(2) = 0.001,   Method: Compositional matrix adjust.
 Identities = 14/40 (35%), Positives = 22/40 (55%)
 Frame = -3

Query: 134 IYVSSPTWENHNAVFSAAGFKDIRPYCYWDAEKRGLDLQG 173
            Y+ +P+W NH  +F  AG  +++ Y Y+D    G D  G
Sbjct: 121 FYIPTPSWGNHTPIFKHAGL-NVKSYRYYDPSTCGFDFAG 5

 Score = 23.9 bits (50), Expect(2) = 0.001,   Method: Compositional matrix adjust.
 Identities = 8/13 (61%), Positives = 10/13 (76%)
 Frame = -2

Query: 112 ALRIGADFLGRWY 124
           +LRIGA F  +WY
Sbjct: 176 SLRIGASFFSKWY 138
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|21450253|ref|NP_659136.1| zinc finger, DHHC domain
containing 5 [Mus musculus]
         (715 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

11289                                                                 197   1e-50
17277                                                                  58   1e-08
24898                                                                  30   3.0  
12175                                                                  30   4.2  
13170                                                                  29   8.5  
>11289
          Length = 2333

 Score =  197 bits (500), Expect = 1e-50,   Method: Compositional matrix adjust.
 Identities = 104/259 (40%), Positives = 147/259 (56%), Gaps = 26/259 (10%)
 Frame = +1

Query: 23  FLVGATTLFFAFTCPGLSLNVSPAVPIYNAIMFLFVLANFSMATFMDPGIFPRAEEDE-- 80
            ++  + LFF F C  L+ +V+PA+P     +F+FV+A     +F DPG+ PRA  DE  
Sbjct: 379 LIIVTSGLFFGFDCVYLAQHVTPAIPAIGGALFIFVMATLLRTSFSDPGVIPRASLDEAA 558

Query: 81  DKEDDFRAP------------LYKTVEIKGIQVRMKWCATCRFYRPPRCSHCSVCDNCVE 128
           D E     P              K + IKG  V++K+C TC+ +RPPR SHCS+CDNCVE
Sbjct: 559 DLERQMEVPNAGSPGTYRPPPRTKEIVIKGQVVKLKYCFTCKLFRPPRASHCSLCDNCVE 738

Query: 129 EFDHHCPWVNNCIGRRNYRYFFLFLLSLTAHIMGVFGFGLLYVLYHIEE---LSGVR--- 182
            FDHHCPWV NC+G+RNYRYF+LF+LSL+ H + +F   L  ++   ++   L+ ++   
Sbjct: 739 RFDHHCPWVGNCVGKRNYRYFYLFILSLSVHCIYIFACVLTNLILRAQQDNFLTAMKDSP 918

Query: 183 TAVTMAVMCVAGLFFIPVAGLTGFHVVLVARGRTTNEQVTGKF---RG--GVNPFTNGCC 237
            +V  A++C   ++   + GL GFH  LVA   TTNE + G F   RG    NP++ G  
Sbjct: 919 ASVIEAIICFFSVW--SIVGLAGFHSYLVASELTTNEDIKGSFTSKRGQESFNPYSKGSI 1092

Query: 238 -NNVSRVLCSSPAPRYLGR 255
             N  +VLC    P  L R
Sbjct: 1093FKNCMQVLCGPTPPSLLDR 1149
>17277
          Length = 490

 Score = 58.2 bits (139), Expect = 1e-08,   Method: Composition-based stats.
 Identities = 25/49 (51%), Positives = 34/49 (69%), Gaps = 2/49 (4%)
 Frame = -1

Query: 112 YRPPRCSHCSVCDNCVEEFDHHCPWVNNCIGRRNYRYF--FLFLLSLTA 158
           YRPPR  HC +C  C+   DHHCPW+NNC+G  N ++F  FLF + L++
Sbjct: 490 YRPPRAHHCRICRRCIRRMDHHCPWINNCVGEYNQKFFIQFLFYVGLSS 344
>24898
          Length = 440

 Score = 30.0 bits (66), Expect = 3.0,   Method: Composition-based stats.
 Identities = 11/34 (32%), Positives = 19/34 (55%)
 Frame = -1

Query: 101 VRMKWCATCRFYRPPRCSHCSVCDNCVEEFDHHC 134
           V++K    C+  RP  C+ C +C  C+++   HC
Sbjct: 299 VKLKLFVICQTLRP-SCTDCPLCSKCIKQQVIHC 201
>12175
          Length = 716

 Score = 29.6 bits (65), Expect = 4.2,   Method: Composition-based stats.
 Identities = 15/44 (34%), Positives = 20/44 (45%), Gaps = 1/44 (2%)
 Frame = +3

Query: 103 MKWCATCRFYRP-PRCSHCSVCDNCVEEFDHHCPWVNNCIGRRN 145
           M +C  C    P    S CSV       + HHC +  NC+ +RN
Sbjct: 291 MYYCVNCHLSTP*ASAS*CSVLTTL---YAHHCLFEYNCLNQRN 413
>13170
          Length = 602

 Score = 28.9 bits (63), Expect = 8.5,   Method: Composition-based stats.
 Identities = 14/42 (33%), Positives = 21/42 (50%)
 Frame = -1

Query: 120 CSVCDNCVEEFDHHCPWVNNCIGRRNYRYFFLFLLSLTAHIM 161
           CSV    V  + H  PW NNC+G  +     L    +T+H++
Sbjct: 164 CSV----VCHYQHTDPWCNNCMGYNSTLNLSLIKEMVTSHVL 51
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31712036|ref|NP_853613.1| eukaryotic translation
initiation factor 5A [Mus musculus]
         (154 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

04206                                                                 193   2e-50
10659                                                                 177   1e-45
02306                                                                  30   0.29 
25279                                                                  29   1.0  
02033                                                                  28   1.5  
31427                                                                  28   1.9  
>04206
          Length = 778

 Score =  193 bits (491), Expect = 2e-50,   Method: Compositional matrix adjust.
 Identities = 96/153 (62%), Positives = 115/153 (75%), Gaps = 3/153 (1%)
 Frame = +1

Query: 1   MADDL-DFETGDAGASATFPMQCSALRKNGFVVLKGRPCKIVEMSTSKTGKHGHAKVHLV 59
           MADD  DFE   +GAS T+P QCSALRKN FVV+KGRPCKIVEMSTSKTGKHGHAKVHLV
Sbjct: 94  MADDHEDFEQTVSGASETYPRQCSALRKNEFVVIKGRPCKIVEMSTSKTGKHGHAKVHLV 273

Query: 60  GIDIFTGKKYEDICPSTHNMDVPNIKRNDFQLIGIQD-GYLSLLQDSGEVREDLRLPEG- 117
            +DIFTGKKYEDICPSTHNM+VPN+ R D   + + D  YLSL+ DSG  R+DL++PE  
Sbjct: 274 ALDIFTGKKYEDICPSTHNMNVPNVTRTDLLYVDVSDEDYLSLMTDSGTTRDDLKMPEAD 453

Query: 118 DLGKEIEQKYDCGEEILITVLSAMTEEAAVAIK 150
           D+  +I+       +  +TVL+AM EE  +A K
Sbjct: 454 DVRNQIKDLIAKESDFYVTVLAAMGEEKVIACK 552
>10659
          Length = 1871

 Score =  177 bits (450), Expect = 1e-45,   Method: Compositional matrix adjust.
 Identities = 87/158 (55%), Positives = 116/158 (73%), Gaps = 7/158 (4%)
 Frame = +1

Query: 1   MADDLDFETGDAGASATFPMQCSALRKNGFVVLKGRPCKIVEMSTSKTGKHGHAKVHLVG 60
           MAD+  F+  D+GAS T P QCSALRK  FVV+KG PCKIV+MSTSKTGKHGHAKVHLV 
Sbjct: 40  MADEEQFDNTDSGASRTIPRQCSALRKGEFVVIKGHPCKIVDMSTSKTGKHGHAKVHLVA 219

Query: 61  IDIFTGKKYEDICPSTHNMDVPNIKRNDFQLIGIQD-GYLSLLQDSGEVREDLRLP--EG 117
           +D+FTGKKYEDICPSTHNM+ P + R ++ +I + D GYLSL+ ++G +R+DL+ P  + 
Sbjct: 220 LDVFTGKKYEDICPSTHNMECPVVTRTEYTVIDVNDEGYLSLMDETGSIRDDLKHPPEDS 399

Query: 118 DLGKEIEQKYDCGEE----ILITVLSAMTEEAAVAIKA 151
           D+ KE++ K D  ++     ++TVL+AM  E  +  K 
Sbjct: 400 DVYKEMKPKLDLLKKEDVNFMVTVLNAMQTEQVMDSKT 513
>02306
          Length = 1100

 Score = 30.4 bits (67), Expect = 0.29,   Method: Compositional matrix adjust.
 Identities = 15/42 (35%), Positives = 23/42 (54%), Gaps = 1/42 (2%)
 Frame = +3

Query: 65  TGKKYEDICPSTHNMDVPNIKR-NDFQLIGIQDGYLSLLQDS 105
           +G+ YE + P+TH  D PN  R   F+ I + +   SL+  S
Sbjct: 366 SGRTYEALYPATHTYDTPNFHRLQYFESINLANISPSLVSAS 491
>25279
          Length = 1402

 Score = 28.9 bits (63), Expect = 1.0,   Method: Compositional matrix adjust.
 Identities = 9/20 (45%), Positives = 14/20 (70%)
 Frame = -3

Query: 65   TGKKYEDICPSTHNMDVPNI 84
            +G+ YE + P+TH  D PN+
Sbjct: 1400 SGRTYEALYPATHTYDTPNL 1341
>02033
          Length = 2181

 Score = 28.1 bits (61), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 11/24 (45%), Positives = 15/24 (62%)
 Frame = -2

Query: 61   IDIFTGKKYEDICPSTHNMDVPNI 84
            IDI  G  Y  +CPST  +D+ N+
Sbjct: 1190 IDICVGLLYLTLCPSTITLDIYNV 1119
>31427
          Length = 519

 Score = 27.7 bits (60), Expect = 1.9,   Method: Compositional matrix adjust.
 Identities = 13/34 (38%), Positives = 20/34 (58%)
 Frame = +3

Query: 55  KVHLVGIDIFTGKKYEDICPSTHNMDVPNIKRND 88
           K+ LVG+ I+  +K+E  CP   N  + + K ND
Sbjct: 168 KMSLVGVRIYYERKHEIXCPLF*NJKI*DFKTND 269
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|224809525|ref|NP_032573.2| male germ cell-associated
kinase isoform 2 [Mus musculus]
         (622 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

01060                                                                 196   3e-50
14126                                                                 180   2e-45
01707                                                                 174   1e-43
29581                                                                 170   1e-42
01966                                                                 102   2e-41
01756                                                                 159   3e-39
04591                                                                 146   2e-35
04138                                                                 120   1e-27
32000                                                                 120   2e-27
06405                                                                 105   7e-23
13592                                                                  99   5e-21
03508                                                                  69   1e-20
00300                                                                  92   5e-19
18921                                                                  89   7e-18
28638                                                                  64   1e-17
12721                                                                  84   2e-16
03240                                                                  84   2e-16
21808                                                                  81   1e-15
19301                                                                  80   3e-15
03294                                                                  80   3e-15
15910                                                                  78   1e-14
18287                                                                  77   2e-14
23319                                                                  75   9e-14
09606                                                                  74   3e-13
01718                                                                  73   3e-13
13212                                                                  72   7e-13
32359                                                                  64   3e-12
09007                                                                  68   9e-12
17975                                                                  68   1e-11
14477                                                                  68   1e-11
31489                                                                  67   2e-11
00392                                                                  67   2e-11
18484                                                                  67   2e-11
30755                                                                  65   9e-11
01392                                                                  65   1e-10
14420                                                                  64   1e-10
19761                                                                  64   2e-10
12453                                                                  62   5e-10
19094                                                                  62   7e-10
26560                                                                  62   8e-10
18401                                                                  62   1e-09
27546                                                                  61   1e-09
27405                                                                  61   1e-09
14116                                                                  59   8e-09
20559                                                                  58   1e-08
07940                                                                  57   1e-08
20640                                                                  57   2e-08
31885                                                                  57   2e-08
26711                                                                  57   3e-08
00715                                                                  54   2e-07
11780                                                                  54   2e-07
11404                                                                  54   2e-07
21079                                                                  53   4e-07
04852                                                                  53   4e-07
16003                                                                  53   5e-07
13066                                                                  52   5e-07
17300                                                                  52   6e-07
36481                                                                  52   6e-07
01106                                                                  52   7e-07
29360                                                                  52   8e-07
24241                                                                  50   2e-06
26009                                                                  45   8e-05
22005                                                                  45   8e-05
13078                                                                  44   1e-04
05084                                                                  44   2e-04
28157                                                                  44   2e-04
02638                                                                  44   2e-04
21433                                                                  44   3e-04
21800                                                                  43   3e-04
07291                                                                  43   4e-04
18481                                                                  43   5e-04
11185                                                                  42   5e-04
16708                                                                  42   9e-04
18996                                                                  41   0.001
17253                                                                  41   0.002
12786                                                                  39   0.004
31757                                                                  38   0.011
37602                                                                  37   0.018
07836                                                                  37   0.028
14104                                                                  36   0.039
00638                                                                  36   0.051
18929                                                                  34   0.18 
20513                                                                  33   0.24 
16350                                                                  32   0.64 
35032                                                                  32   0.66 
13840                                                                  30   2.4  
15549                                                                  24   3.1  
36002                                                                  30   3.4  
29722                                                                  29   5.0  
31595                                                                  29   5.9  
17516                                                                  29   6.0  
>01060
          Length = 1800

 Score =  196 bits (497), Expect = 3e-50,   Method: Compositional matrix adjust.
 Identities = 105/294 (35%), Positives = 178/294 (60%), Gaps = 10/294 (3%)
 Frame = +1

Query: 1   MNRYTTMKQLGDGTYGSVLMGKSNESGELVAIKRMKRKFYSWDEC--MNLREVKSLKKLN 58
           ++  T  +++G+GTYG V   +   +G  +A+K+++ +  S D      +RE+  L++L 
Sbjct: 70  LSDLTDFQKIGEGTYGVVYKCRHRATGRKLAMKKIRLR-GSEDGVPSSAIREIAMLRELR 246

Query: 59  HANVIKLKEVIRENDHLYFVFEYMKENLYQLMKDRNKLFPESVI------RNIMYQILQG 112
           H N++ L++VI E++ L+ VFE++  +L ++  D+   FPE V+      ++ ++QI+ G
Sbjct: 247 HTNIVCLEDVIMEDERLFLVFEFLSMDL-KMYIDK---FPEGVVLDRRLVKSYVFQIVTG 414

Query: 113 LAFIHKHGFFHRDMKPENLLCMGPELVKIADFGLARELRSQP--PYTDYVSTRWYRAPEV 170
           + F H+    HRD+KP+NLL      +KIADFG+AR   + P   YT  V T WYRAPE+
Sbjct: 415 IXFCHQRRIVHRDLKPQNLLINHTGAIKIADFGMARTF-ALPVRAYTHEVVTLWYRAPEI 591

Query: 171 LLRSSVYSSPIDVWAVGSIMAELYTFRPLFPGTSEVDEIFKICQVLGTPKKSDWPEGYQL 230
           L+ +S YS+P+DVW++G+I A++    P+F G SE+D++FKI +++GTP +  WPE ++L
Sbjct: 592 LMGASKYSTPVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIFRIIGTPTEQTWPEFHKL 771

Query: 231 ASSMNFRFPQCIPINLKTLIPNASSEAIQLMTEMLNWDPKKRPTASQALKHPYF 284
             + N  FP      L   + +  S  + L+   L  DP +R +  + L+H YF
Sbjct: 772 -PAFNGMFPLWKEGKLSETLTDLDSLGLDLIERTLKCDPAQRISCKKMLQHAYF 930
>14126
          Length = 1265

 Score =  180 bits (456), Expect = 2e-45,   Method: Compositional matrix adjust.
 Identities = 108/296 (36%), Positives = 170/296 (57%), Gaps = 13/296 (4%)
 Frame = +3

Query: 3   RYTTMKQLGDGTYGSVLMGKS-NESGELVAIKRMKRKFYSWDE---CMNLREVKSLKKLN 58
           +Y  +  +G+G YG+V   +     GE VA+KR++    + +E    M +RE+  LK+L 
Sbjct: 192 KYEEVAVIGNGAYGTVYKARDLRNQGEFVAMKRIR--LNNTEEGMPMMAIREISMLKQLE 365

Query: 59  ---HANVIKLKEV----IREND-HLYFVFEYMKENLYQ-LMKDRNKLFPESVIRNIMYQI 109
              H NV++L +V    I + +  L  VFEY++ +L   L K  +       I+++M Q+
Sbjct: 366 QYEHPNVVRLLDVSHNTITDREIRLNLVFEYIEHDLATYLAKCPSPGLGPDRIKDLMLQL 545

Query: 110 LQGLAFIHKHGFFHRDMKPENLLCMGPELVKIADFGLARELRSQPPYTDYVSTRWYRAPE 169
           L G+ F+H +   HRD+KP+NLL      +K+ADFGLAR        T  V T WYR+PE
Sbjct: 546 LNGVDFLHSNRIVHRDLKPQNLLISKDGRLKLADFGLARIYSFHMALTTVVVTLWYRSPE 725

Query: 170 VLLRSSVYSSPIDVWAVGSIMAELYTFRPLFPGTSEVDEIFKICQVLGTPKKSDWPEGYQ 229
           VL+++  Y + +D+W+ G I AEL+T R LF G+SE D++ KI +V+G P   DWPEG  
Sbjct: 726 VLMQAE-YGTSVDIWSCGCIFAELFTRRALFKGSSEFDQLKKIFEVIGLPPAGDWPEGVS 902

Query: 230 LASSMNFRFPQCIPINLKTLIPNASSEAIQLMTEMLNWDPKKRPTASQALKHPYFQ 285
           +  +    F    P+ L+TL+P    +A  LM +ML +   +R ++ ++L HPY +
Sbjct: 903 VHRN---SFRPTPPVPLQTLVPEMDPQAKDLMEKMLVFKSGRRISSRESLLHPYLR 1061
>01707
          Length = 757

 Score =  174 bits (440), Expect = 1e-43,   Method: Compositional matrix adjust.
 Identities = 89/223 (39%), Positives = 137/223 (61%), Gaps = 6/223 (2%)
 Frame = +1

Query: 1   MNRYTTMKQLGDGTYGSVLMGKSNESGELVAIKRMKRKFYSWDEC-----MNLREVKSLK 55
           M +Y  + ++G+G+YG V   ++ E+ +LVAIK    KF   ++      + +RE++ LK
Sbjct: 61  MEKYEKIGKIGEGSYGVVFKCRNKETSQLVAIK----KFVESEDDPLIKKIAMREIRMLK 228

Query: 56  KLNHANVIKLKEVIRENDHLYFVFEYMKENLYQLMKDRNKLFPESVIRNIMYQILQGLAF 115
           +L H N+++L EV R    L+ VF+Y+   L   +    +  PE +++ I+YQ L  + F
Sbjct: 229 QLKHPNLVRLIEVFRRKKRLHLVFDYVDHTLLNELDRYPRGLPEPMVKRIIYQTLLAVNF 408

Query: 116 IHKHGFFHRDMKPENLLCMGPELVKIADFGLARELRS-QPPYTDYVSTRWYRAPEVLLRS 174
            H++   HRD+KPEN+L      VK+ DFG AR L      YTDYV+TRWYRAPE+L+  
Sbjct: 409 CHQYNTIHRDVKPENILITRQGQVKLCDFGFARILTGPGDEYTDYVATRWYRAPELLVGD 588

Query: 175 SVYSSPIDVWAVGSIMAELYTFRPLFPGTSEVDEIFKICQVLG 217
           + Y  P+DVWA+G + AEL T + L+PG S+VD++  I + LG
Sbjct: 589 TQYGPPVDVWAIGCVFAELLTGQALWPGRSDVDQLHLIRKTLG 717
>29581
          Length = 1278

 Score =  170 bits (431), Expect = 1e-42,   Method: Compositional matrix adjust.
 Identities = 92/235 (39%), Positives = 137/235 (58%), Gaps = 3/235 (1%)
 Frame = -2

Query: 54   LKKLNHANVIKLKEVI--RENDHLYFVFEYMKENLYQLMKDRNKLFPESVIRNIMYQILQ 111
            L  L H N+++L+EV+  +  D L+ V EY +++L  L+ +    F ES ++ I+ Q+L+
Sbjct: 1193 LLNLRHQNIVQLQEVVVGKSLDSLFLVMEYCEQDLASLLDNMPAPFSESQVKCIVLQLLK 1014

Query: 112  GLAFIHKHGFFHRDMKPENLLCMGPELVKIADFGLAREL-RSQPPYTDYVSTRWYRAPEV 170
            GL ++H+    HRD+K  NLL      VKIADFGLAR   + Q P T  V T WYRAPE+
Sbjct: 1013 GLRYLHEAFIIHRDLKVSNLLMTDKGCVKIADFGLARNYGKPQKPMTPKVVTLWYRAPEL 834

Query: 171  LLRSSVYSSPIDVWAVGSIMAELYTFRPLFPGTSEVDEIFKICQVLGTPKKSDWPEGYQL 230
            L  S  +S+ ID+W+ G I+ EL   +PL PG S++ +I  I ++LGTP  + WP   QL
Sbjct: 833  LFGSKTHSTAIDMWSAGCILGELLGHKPLMPGRSDLQQIELIMELLGTPNDTIWPGFSQL 654

Query: 231  ASSMNFRFPQCIPINLKTLIPNASSEAIQLMTEMLNWDPKKRPTASQALKHPYFQ 285
             +   F   +    NL+   P  S   I+L+  +  + P+KR TA   L+H YF+
Sbjct: 653  PAFEQFTLKKQPYNNLRHTFPWLSESGIRLLNGLFMYHPQKRATAEDCLEHSYFK 489
>01966
          Length = 1735

 Score =  102 bits (254), Expect(2) = 2e-41,   Method: Compositional matrix adjust.
 Identities = 53/133 (39%), Positives = 85/133 (63%), Gaps = 8/133 (6%)
 Frame = -1

Query: 48   LREVKSLKKLNHANVIKLKEVIRENDHLYFVFEYMKENLYQLMKDRNKLFPESVI----- 102
            +RE+  L++L H N++ L++VI E++ L+ VFE++  +L ++  D+   FPE V+     
Sbjct: 1570 IREIAMLRELRHTNIVCLEDVIMEDERLFLVFEFLSMDL-KMYIDK---FPEGVVLDRRL 1403

Query: 103  -RNIMYQILQGLAFIHKHGFFHRDMKPENLLCMGPELVKIADFGLARELRSQP--PYTDY 159
             ++ ++QI+ G+ F H+    HRD+KP+NLL      +KIADFG+AR   + P   YT  
Sbjct: 1402 VKSYVFQIVTGINFCHQRRIVHRDLKPQNLLINHTGAIKIADFGMARTF-ALPVRAYTHE 1226

Query: 160  VSTRWYRAPEVLL 172
            V T WYRAPE+L+
Sbjct: 1225 VVTLWYRAPEILM 1187

 Score = 85.5 bits (210), Expect(2) = 2e-41,   Method: Compositional matrix adjust.
 Identities = 40/111 (36%), Positives = 67/111 (60%)
 Frame = -3

Query: 174  SSVYSSPIDVWAVGSIMAELYTFRPLFPGTSEVDEIFKICQVLGTPKKSDWPEGYQLASS 233
            +S YS+P+DVW++G+I A++    P+F G SE+D++FKI +++GTP +  WPE ++L  +
Sbjct: 1184 ASKYSTPVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIFRIIGTPTEQTWPEFHKLP-A 1008

Query: 234  MNFRFPQCIPINLKTLIPNASSEAIQLMTEMLNWDPKKRPTASQALKHPYF 284
             N  FP      L   + +  S  + L+   L  DP +R +  + L+H YF
Sbjct: 1007 FNGMFPLWKEGKLSETLTDLDSLGLDLIERTLKCDPAQRISCKKMLQHAYF 855
>01756
          Length = 1858

 Score =  159 bits (402), Expect = 3e-39,   Method: Compositional matrix adjust.
 Identities = 100/303 (33%), Positives = 158/303 (52%), Gaps = 21/303 (6%)
 Frame = -3

Query: 3    RYTTMKQLGDGTYGSVLMGKSNESGELVAIKRM-----KRKFYSWDECMNLREVKSLKKL 57
            +Y  + ++G GT+G V   +  ++ ++VA+K++     K  F        LRE+K L+ L
Sbjct: 1739 KYEKLAKIGQGTFGEVFKARCKKTKQVVAMKKVLMDNEKEGF----PITALREIKILQLL 1572

Query: 58   NHANVIKLKEVI--------RENDHLYFVFEYMKENLYQLMKDRNKLFPESVIRNIMYQI 109
            NH NV+ L E+         R     Y VFE+ + +L  L+ + + +F    I+ +M Q+
Sbjct: 1571 NHENVVDLIEICSTKATSANRYKSMFYLVFEFCEHDLAGLLSNMSVVFNLPEIKEVMKQL 1392

Query: 110  LQGLAFIHKHGFFHRDMKPENLLCMGPELVKIADFGLAR----ELRSQPPYTDYVSTRWY 165
            + GL +IH++   HRDMK  N+L     ++K+ADFGLAR     LR    YT+ V T WY
Sbjct: 1391 MNGLYYIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRVVTLWY 1212

Query: 166  RAPEVLLRSSVYSSPIDVWAVGSIMAELYTFRPLFPGTSEVDEIFKICQVLGTPKKSDWP 225
            R PE+LL    YS+ ID W  G IMAE++T  P+  GT+E +++  I Q+ G+     WP
Sbjct: 1211 RPPELLLGDRNYSTAIDQWGAGCIMAEMWTRNPIMQGTTEQNQLTLITQLCGSITPEVWP 1032

Query: 226  EGYQLASSMNFRFPQC----IPINLKTLIPNASSEAIQLMTEMLNWDPKKRPTASQALKH 281
               +L    +   PQ     +   L+  I +A +  +      L+  P KR  + +AL H
Sbjct: 1031 GVERLELYNSLDLPQGNKRKVKERLRYYIKDAYALDLLDKLLALD--PGKRVNSDEALSH 858

Query: 282  PYF 284
             +F
Sbjct: 857  DFF 849
>04591
          Length = 1117

 Score =  146 bits (369), Expect = 2e-35,   Method: Compositional matrix adjust.
 Identities = 85/249 (34%), Positives = 127/249 (51%), Gaps = 10/249 (4%)
 Frame = -2

Query: 48   LREVKSLKKLNHANVIKLKEVI--------RENDHLYFVFEYMKENLYQLMKDRNKLFPE 99
            LRE+K L++L H NV++L+E+         R     Y +FEY   +L  L+ +    F  
Sbjct: 1077 LREIKILQQLEHENVVQLQEICHTQAGPYNRYKSTFYLIFEYCDYDLAGLLNNLRVKFSL 898

Query: 100  SVIRNIMYQILQGLAFIHKHGFFHRDMKPENLLCMGPELVKIADFGLARELRSQPPYTDY 159
            +  +N+M Q+L GL +IH     HRD+K  N+L     ++K+ADFGL+R        T+ 
Sbjct: 897  ADKKNLMSQLLNGLFYIHTKQILHRDIKAANILLTRDGVLKLADFGLSRPWVKSKRLTNR 718

Query: 160  VSTRWYRAPEVLLRSSVYSSPIDVWAVGSIMAELYTFRPLFPGTSEVDEIFKICQVLGTP 219
            V T WYR PE+LL    Y   ID+W VG IMAE+++ +PL  G SE  ++  I  + G+ 
Sbjct: 717  VVTLWYRPPELLLGEREYGPEIDMWGVGCIMAEMWSRKPLMQGRSEQHQLSLITDLCGSL 538

Query: 220  KKSDWPEGYQLASSMNFRFPQCIPINLKTLIPN--ASSEAIQLMTEMLNWDPKKRPTASQ 277
                WP   +L        PQ  P  +K  + +   + E  +L+   L  DP +R     
Sbjct: 537  NAEVWPGVTKLELYGKLDLPQGKPRKVKERMLDLLKNKEGAELIDIFLRLDPGQRMNCDN 358

Query: 278  ALKHPYFQV 286
            AL H +F V
Sbjct: 357  ALSHDFFWV 331
>04138
          Length = 800

 Score =  120 bits (302), Expect = 1e-27,   Method: Compositional matrix adjust.
 Identities = 69/185 (37%), Positives = 100/185 (54%), Gaps = 10/185 (5%)
 Frame = +1

Query: 113 LAFIHKHGFFHRDMKPENLLCMGPELVKIADFGLAR----ELRSQPPYTDYVSTRWYRAP 168
           L +IH++   HRDMK  N+L     ++K+ADFGLAR     LR    YT+ V T WYR P
Sbjct: 52  LYYIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRVVTLWYRPP 231

Query: 169 EVLLRSSVYSSPIDVWAVGSIMAELYTFRPLFPGTSEVDEIFKICQVLGTPKKSDWPEGY 228
           E+LL    YS+ ID W  G IMAE++T  P+  GT+E +++  I Q+ G+     WP   
Sbjct: 232 ELLLGDRNYSTAIDQWGAGCIMAEMWTRNPIMQGTTEQNQLTLITQLCGSITPEVWPGVT 411

Query: 229 QLASSMNFRFPQCIPINLKTLIPNASSEAIQ------LMTEMLNWDPKKRPTASQALKHP 282
           QL  SM  +    +    K +I +  +  ++      L   +L  DP +R +A +AL H 
Sbjct: 412 QL--SMYHQIKGALAAGRKNIIRDRFARILKDPYGLDLFERLLKMDPSQRISADEALNHD 585

Query: 283 YFQVG 287
           +F VG
Sbjct: 586 FFWVG 600
>32000
          Length = 644

 Score =  120 bits (300), Expect = 2e-27,   Method: Compositional matrix adjust.
 Identities = 66/169 (39%), Positives = 97/169 (57%), Gaps = 1/169 (0%)
 Frame = -1

Query: 139 VKIADFGLAREL-RSQPPYTDYVSTRWYRAPEVLLRSSVYSSPIDVWAVGSIMAELYTFR 197
           +KIADFGLAR        YT  V T WYRAPE+LL    YS P+D+W++G I  E+ T R
Sbjct: 572 MKIADFGLARVFGLPVRTYTHEVITLWYRAPEILLGCRFYSVPVDIWSLGCIFVEMMTRR 393

Query: 198 PLFPGTSEVDEIFKICQVLGTPKKSDWPEGYQLASSMNFRFPQCIPINLKTLIPNASSEA 257
            LFPG SE+D++++I + LGTP +  WP G          FP+    NL+T++ + S   
Sbjct: 392 ALFPGDSEIDQLYRIFRTLGTPDEKVWP-GVSKLPDYKPTFPKWPLKNLETVV-SLSKVG 219

Query: 258 IQLMTEMLNWDPKKRPTASQALKHPYFQVGQVLGSSAHHLDTKQTLHKQ 306
           + L+  ML ++P +R +A  A++HPYF   + +  +  H      + KQ
Sbjct: 218 LDLLKRMLTYNPNRRISARSAMRHPYFNDMKRMT*TDLHAAMHTAIQKQ 72
>06405
          Length = 1965

 Score =  105 bits (261), Expect = 7e-23,   Method: Compositional matrix adjust.
 Identities = 93/353 (26%), Positives = 156/353 (44%), Gaps = 12/353 (3%)
 Frame = +1

Query: 9   QLGDGTYGSVLMGKSNESGELVAIKRMKRKFYSWDECMNLREVKSLKKLNHANVIKLKEV 68
           +LG G YG V         ++VA+K +K    + ++   L E   +K++ H N+++L  V
Sbjct: 280 RLGGGQYGDVYEAMWKRYNKIVAVKTLKEDTMALNDF--LEEAAIMKEMKHPNLVQLLGV 453

Query: 69  IRENDHLYFVFEYMKE-NLYQLMKDRNKLFPESVIRNIMY---QILQGLAFIHKHGFFHR 124
                  Y V E+M   NL   ++   +   E+    +MY   QI  G+A++    F HR
Sbjct: 454 CTREPPFYIVTEFMPHGNLLDYLRSSTR--EENGPTALMYMATQIASGMAYLETKNFIHR 627

Query: 125 DMKPENLLCMGPELVKIADFGLARELRSQPPYTDYVSTRW---YRAPEVLLRSSVYSSPI 181
           D+   N L     +VK+ADFGLAR ++    YT ++  ++   + APE L  +  +S+  
Sbjct: 628 DLAARNCLVADSNMVKVADFGLARLMKDD-TYTAHIGAKFPIKWTAPEGLAFNR-FSTRS 801

Query: 182 DVWAVGSIMAELYTF-RPLFPGTSEVDEIFKICQVLGTPKKSDWPEGYQLASSMNFRFPQ 240
           D+WA G ++ EL T+    +PG  E+ E++ + +            GY++          
Sbjct: 802 DIWAFGVLLWELATYGMSPYPGV-ELTEVYHLLE-----------RGYRMERP------- 924

Query: 241 CIPINLKTLIPNASSEAIQLMTEMLNWDPKKRPTASQALKHPYFQVGQVLGSSAHHLDTK 300
                     P   ++   LM +   WDPK RPT     K  +F +  +   S+   + +
Sbjct: 925 ----------PGTPADVYILMLKCWQWDPKDRPT----FKEIHFLLENMFEKSSICEEVE 1062

Query: 301 QTLH----KQLQPLEPKPSSSERDPKPLPNILDQPAGQPQPKQGHQPLQTIQP 349
           + L     KQ+ P  P+ + S     P       P G P   + HQP  T+ P
Sbjct: 1063KELEKNDKKQMPPCPPRKTGSPLSTAP----TSHPRGPPTQGRRHQP--TVAP 1203
>13592
          Length = 980

 Score = 99.0 bits (245), Expect = 5e-21,   Method: Compositional matrix adjust.
 Identities = 75/289 (25%), Positives = 132/289 (45%), Gaps = 9/289 (3%)
 Frame = +2

Query: 9   QLGDGTYGSVLMGKSNESGELVAIKRMKRKFYSWDECMNL-REVKSLKKLNHANVIKLKE 67
           ++G G +G V    +N +GEL+A+K +  +        N+  E+K L+ + H N+++   
Sbjct: 5   KIGQGRFGKVYTAVNNNTGELMAMKEIAIQPGETRALKNVAEELKILEGIKHKNLVRYYG 184

Query: 68  VIRENDHLYFVFEYMKENLYQLMKDRNKLFPESVIRNIMYQILQGLAFIHKHGFFHRDMK 127
           +    + L    E   E   + + +     PE++ R    Q+L G+A +HKHG  HRD+K
Sbjct: 185 IEVHREELLIFMELCSEGTLESLVELTGGLPEALSRRFTAQLLSGVAELHKHGIVHRDIK 364

Query: 128 PENL-LCMGPELVKIADFGLARELRSQP----PYTDYVSTRWYRAPEVLLR--SSVYSSP 180
             N+ L  G   +K+ DFG A ++++          YV T+ Y APEV  +  S  +   
Sbjct: 365 TANIFLVDGSNSLKLGDFGSAVKIQAHTTVPGELQGYVGTQAYMAPEVFTKTNSDGHGRL 544

Query: 181 IDVWAVGSIMAELYTF-RPLFPGTSEVDEIFKICQVLGTPKKSDWPEGYQLASSMNFRFP 239
            D+W+VG ++ E+ +  RP     ++ D  F+I   +G  +K   PE             
Sbjct: 545 ADIWSVGCVVVEMASGKRPW----AQFDSNFQIMFKVGMGEKPQAPE------------- 673

Query: 240 QCIPINLKTLIPNASSEAIQLMTEMLNWDPKKRPTASQALKHPYFQVGQ 288
                       + S E    +   L  DPK+R +A + L+  + + G+
Sbjct: 674 ------------SLSQEGHDFIDHCLQHDPKQRLSAIELLEQNFCKSGR 784
>03508
          Length = 1463

 Score = 68.6 bits (166), Expect(2) = 1e-20,   Method: Compositional matrix adjust.
 Identities = 35/108 (32%), Positives = 62/108 (57%), Gaps = 3/108 (2%)
 Frame = +1

Query: 97  FPESVIRNIMYQILQGLAFIHKHGFFHRDMKPENLLC-MGPELVKIADFGLARELRSQPP 155
           F +  IR  +Y++++ L F H  G  HRD+KP N++     + +++ D+GLA        
Sbjct: 862 FTDYDIRFYLYELMKALDFCHSMGIMHRDVKPHNVMIDHENKKLRLIDWGLAEFYHPGME 1041

Query: 156 YTDYVSTRWYRAPEVLLRSSVYSSPIDVWAVGSIMAELYTFR--PLFP 201
           Y   V++R+++ PE+LL   +Y   +D+W++G + A +  FR  PL P
Sbjct: 1042YNVRVASRYFKGPELLLDYQMYDYSLDMWSLGCMFASM-IFRKEPLLP 1182

 Score = 49.3 bits (116), Expect(2) = 1e-20,   Method: Compositional matrix adjust.
 Identities = 29/97 (29%), Positives = 47/97 (48%), Gaps = 10/97 (10%)
 Frame = +2

Query: 198  PLFPGTSEVDEIFKICQVLGTPKKSDWPEGYQLASSMNF----------RFPQCIPINLK 247
            P F G    D++ +I +VLGT     + E YQ+     F          R+ + +    +
Sbjct: 1172 PFFHGHDNYDQLVRIAKVLGTDDLYGYIEKYQIDLDPRFNDILGRHSRKRWERFVHSENQ 1351

Query: 248  TLIPNASSEAIQLMTEMLNWDPKKRPTASQALKHPYF 284
             LI   S EA+  + ++L +D  +R TA +A+ HPYF
Sbjct: 1352 HLI---SPEALDFLDKLLRYDHNERLTAREAMDHPYF 1453
>00300
          Length = 2318

 Score = 92.4 bits (228), Expect = 5e-19,   Method: Compositional matrix adjust.
 Identities = 72/295 (24%), Positives = 127/295 (43%), Gaps = 11/295 (3%)
 Frame = -1

Query: 3    RYTTMKQLGDGTYGSVLMGKSNESGELVAIKRMKRKFYSWDECMNLRE----VKSLKKLN 58
            R+    ++G+G +G V    +  +GEL+A+K MK   +  ++   LRE    +K  + + 
Sbjct: 1655 RWQRGNKIGEGQFGKVYTAVNMSTGELMALKEMK---FQPNDLQQLREMCDEIKIFEGIQ 1485

Query: 59   HANVIKLKEVIRENDHLYFVFEYMKENLYQLMKDRNKL-FPESVIRNIMYQILQGLAFIH 117
            H N++K   V    D +    EY        +++  K+  PE +IR    +I+  +  +H
Sbjct: 1484 HENLVKYYGVEVHKDEMLMFMEYCDTGT---IEEAAKMGLPEYLIRRYTREIVLAVNHLH 1314

Query: 118  KHGFFHRDMKPENLLCMGPELVKIADFGLARELRSQP----PYTDYVSTRWYRAPEVLLR 173
            ++   HRD+K  N+       VK+ DFG + +L+S       + + V T  Y APEV  +
Sbjct: 1313 ENSIVHRDIKGANIFLTSNGHVKLGDFGCSVKLKSHTTMPGEFHNLVGTTAYMAPEVFTQ 1134

Query: 174  SSV--YSSPIDVWAVGSIMAELYTFRPLFPGTSEVDEIFKICQVLGTPKKSDWPEGYQLA 231
            +    Y    D+W++G ++ E+ T                     G     D    YQ+ 
Sbjct: 1133 NDQGGYGRAADIWSLGCVVIEMAT---------------------GKRPWHDLDNNYQIM 1017

Query: 232  SSMNFRFPQCIPINLKTLIPNASSEAIQLMTEMLNWDPKKRPTASQALKHPYFQV 286
              +       +P +L       S E    +  ++  DP +R  ASQ L H + +V
Sbjct: 1016 YKVGIGHKPAVPDSL-------SVEGKHFLDLIMCHDPAQRALASQLLDHTFTKV 873
>18921
          Length = 697

 Score = 88.6 bits (218), Expect = 7e-18,   Method: Compositional matrix adjust.
 Identities = 56/199 (28%), Positives = 103/199 (51%), Gaps = 2/199 (1%)
 Frame = +2

Query: 2   NRYTTMKQLGDGTYGSVLMGKSNESGELVAIKRMKRKFYSWDECMNLREVKSLKKLNHAN 61
           + +  + +LG+G+YGSV      E+G+++AIK++       D    ++E+  +++ +   
Sbjct: 29  DVFDILGKLGEGSYGSVFKSLHKETGQVLAIKQVP---VDTDLQEIIKEISIMQQCDSKY 199

Query: 62  VIKLKEVIRENDHLYFVFEYMKE-NLYQLMKDRNKLFPESVIRNIMYQILQGLAFIHKHG 120
           ++K      +N  L+ V EY    ++  +M+ RNK   E  I  I+Y  L+GL ++H   
Sbjct: 200 IVKYYGSYFKNTDLWIVMEYCGAGSVSDIMRLRNKTLVEREIATILYYTLKGLXYLHSRR 379

Query: 121 FFHRDMKPENLLCMGPELVKIADFGLARELR-SQPPYTDYVSTRWYRAPEVLLRSSVYSS 179
             HRD+K  N+L       K+ADFG+A +L  +       + T ++ APEV ++   Y  
Sbjct: 380 KIHRDIKAGNILLNNEGHAKLADFGVAGQLTDTMAKRNTVIGTPYWMAPEV-IQEIGYDC 556

Query: 180 PIDVWAVGSIMAELYTFRP 198
             D+W++G    E+   +P
Sbjct: 557 VADIWSLGITALEMAEGKP 613
>28638
          Length = 1458

 Score = 63.9 bits (154), Expect(2) = 1e-17,   Method: Compositional matrix adjust.
 Identities = 38/100 (38%), Positives = 57/100 (57%), Gaps = 4/100 (4%)
 Frame = -1

Query: 103 RNIMYQILQGLAFIH--KHGFFHRDMKPENLLCMGPE--LVKIADFGLARELRSQPPYTD 158
           R    Q+   L F+   +    H D+KPEN+L   P+   +KI DFG + +L  Q  Y  
Sbjct: 828 RKFAQQLCTALLFLATPEMNIIHCDLKPENILLCNPKRSAIKIVDFGSSCQL-GQRIY-Q 655

Query: 159 YVSTRWYRAPEVLLRSSVYSSPIDVWAVGSIMAELYTFRP 198
           Y+ +R+YR+PEVLL    Y   ID+W++G I+ E++T  P
Sbjct: 654 YIQSRFYRSPEVLLGVP-YDLAIDMWSLGCILVEMHTGEP 538

 Score = 43.9 bits (102), Expect(2) = 1e-17,   Method: Compositional matrix adjust.
 Identities = 31/102 (30%), Positives = 52/102 (50%), Gaps = 8/102 (7%)
 Frame = -3

Query: 1    MNRYTTMKQLGDGTYGSVLMGKSNESGELVAIKRMKRK--FYSWDECMNLREVKSLKKLN 58
            ++RY     +G G++G V+    +   E VAIK +K K  F +  +     EVK L+ +N
Sbjct: 1150 LDRYEIDSLIGKGSFGQVVKAYDHGDQEQVAIKIIKNKKPFLNQAQI----EVKLLELMN 983

Query: 59   HAN------VIKLKEVIRENDHLYFVFEYMKENLYQLMKDRN 94
              +      +++LK      +HL  VFE +  NLY L+++ N
Sbjct: 982  RHDADNXYYIVRLKRHFMFRNHLCLVFELLSYNLYDLLRNTN 857

 Score = 33.5 bits (75), Expect = 0.28,   Method: Compositional matrix adjust.
 Identities = 26/99 (26%), Positives = 40/99 (40%), Gaps = 5/99 (5%)
 Frame = -2

Query: 128 PENLLCMGPELVKIADFGLARELRSQPPYTDYVSTRWYRAPEVLLRSSVYSSPIDVWAVG 187
           P    C+ P +V+      A  +     YT        RA     R      P+  W + 
Sbjct: 746 PRTFCCVTPSVVQSKSSTSAALVSWDKGYTSTS-----RAGSTGRRRCYXXCPM-TWPLT 585

Query: 188 SIMAELYTFR-----PLFPGTSEVDEIFKICQVLGTPKK 221
                +Y +R     PLF G++E D++ KI +VLG P +
Sbjct: 584 CGXWAVYWWRCTXGNPLFAGSNEFDQMMKIVEVLGVPPR 468
>12721
          Length = 821

 Score = 83.6 bits (205), Expect = 2e-16,   Method: Compositional matrix adjust.
 Identities = 53/193 (27%), Positives = 99/193 (51%), Gaps = 1/193 (0%)
 Frame = +1

Query: 9   QLGDGTYGSVLMGKSNESGELVAIKRMKRKFYSWDECMNLREVKSLKKLNHANVIKLKEV 68
           ++G+G+ G V +  S + G  +A+K+M  +     E +   EV  ++  +H N++++   
Sbjct: 109 KIGEGSTGIVCIATSRD-GRQMAVKKMDLRKQQRRELL-FNEVVVMRDYHHPNIVEMYNS 282

Query: 69  IRENDHLYFVFEYMKENLYQLMKDRNKLFPESVIRNIMYQILQGLAFIHKHGFFHRDMKP 128
              ND L+ V E+M+      +   N++  E  I  +    L+ LAF+H +G  HRD+K 
Sbjct: 283 YLVNDELWVVMEFMEGGALTDIVTNNRM-DEVQIATVCRACLKALAFLHANGVIHRDIKS 459

Query: 129 ENLLCMGPELVKIADFGLAREL-RSQPPYTDYVSTRWYRAPEVLLRSSVYSSPIDVWAVG 187
           +++L      VK+ DFG   ++ +        V T ++ APEV+ R   Y   +D+W++G
Sbjct: 460 DSILLSHDGKVKLXDFGFCAQVTQDLQKRKSLVGTPYWMAPEVISRLP-YGPEVDIWSLG 636

Query: 188 SIMAELYTFRPLF 200
            ++ E+    P F
Sbjct: 637 IMVMEMIDAEPPF 675
>03240
          Length = 1683

 Score = 83.6 bits (205), Expect = 2e-16,   Method: Compositional matrix adjust.
 Identities = 66/270 (24%), Positives = 121/270 (44%), Gaps = 50/270 (18%)
 Frame = -3

Query: 4    YTTMKQLGDGTYGSVLMGKSNESGELVAIKRMKR-KFYSWDECMNLR-EVKSLKKLNHAN 61
            +  +K LG G +G V + + N++G L A+K +++      ++  +++ E   L + ++  
Sbjct: 1285 FEKIKTLGVGAFGEVSLCRKNDTGMLYAMKTLRKSDVLKRNQVAHVKAERDILAEADNEW 1106

Query: 62   VIKLKEVIRENDHLYFVFEYMKENLYQLMKDRNKLFPESVIRNIMYQILQGLAFIHKHGF 121
            V+KL    +++++LYFV +Y+       +  R ++  E + R  + +++Q +  +H+ GF
Sbjct: 1105 VVKLYYSFQDHNYLYFVMDYVPGGDLMGLLIRMEILDEPLARFYVAELVQAIESVHRMGF 926

Query: 122  FHRDMKPENLLCMGPELVKIADFGLA---------------------------------- 147
             HRD+KP+N+L      +K+ DFGL                                   
Sbjct: 925  IHRDIKPDNILIDRNGHIKLTDFGLCTGFRWTHNSKYYQRDGTHARQDSMEVKCQLDEQC 746

Query: 148  ----------RELRSQPPYT-DYVSTRWYRAPEVLLRSSVYSSPIDVWAVGSIMAELYTF 196
                      R  R Q       V T  Y APEVL R   Y+S  D W+VG I+ E+   
Sbjct: 745  QCEILKPLERRRKREQRCLAHSLVGTPNYIAPEVLSRLGGYTSVCDWWSVGVILFEMLVG 566

Query: 197  RPLFPGTSEVDEIFKIC---QVLGTPKKSD 223
             P F   +  +  +K+     +L  P++S+
Sbjct: 565  HPPFYANTPAETQYKVINWKDMLKIPRESN 476
>21808
          Length = 1011

 Score = 81.3 bits (199), Expect = 1e-15,   Method: Compositional matrix adjust.
 Identities = 55/188 (29%), Positives = 99/188 (52%), Gaps = 5/188 (2%)
 Frame = +1

Query: 30  VAIKRMKRKFYSWDECMNLREVKSLKKLNHANVIKLKEVIRENDHLYFVFEYMKE-NLYQ 88
           VAIK +K    + D    L E + +KKL H  +I+L  V  ++D ++ + E MK  +L +
Sbjct: 28  VAIKTLKSG--TMDPKDFLAEAQIMKKLRHPKLIQLYAVCTQDDPIFIITELMKNGSLLE 201

Query: 89  LMKDRNKLFPESVIRNIMYQILQGLAFIHKHGFFHRDMKPENLLCMGPELVKIADFGLAR 148
            ++ + ++     + +I  QI  G+A++    + HRD+   N+L      VKIADFGLAR
Sbjct: 202 FLQGKGRVLKLPALIDIGAQIACGMAYLESQNYIHRDLAARNILVSDNNTVKIADFGLAR 381

Query: 149 ELRSQPPYTDYVSTRW---YRAPEVLLRSSVYSSPIDVWAVGSIMAELYTF-RPLFPGTS 204
            ++ +  Y   V  R+   + APE     + ++   DVW+ G ++ E  T+ R  +PG +
Sbjct: 382 VIK-EDEYEARVGARFPIKWTAPEA-ANYNRFTIKSDVWSFGILLTETVTYGRVPYPGMT 555

Query: 205 EVDEIFKI 212
             + + ++
Sbjct: 556 NAEVLHQV 579
>19301
          Length = 712

 Score = 79.7 bits (195), Expect = 3e-15,   Method: Compositional matrix adjust.
 Identities = 45/142 (31%), Positives = 78/142 (54%), Gaps = 1/142 (0%)
 Frame = +2

Query: 5   TTMKQLGDGTYGSVLMGKSNESGELVAIKRMKRKFYSWDECMNLREVKSLKKLNHANVIK 64
           T ++ LG G  G+V +GK     E VA+K+++         +   ++++L+KLNH N+I 
Sbjct: 314 TDLEWLGSGAQGAVFLGKL--CAEEVAVKKVRD--------IKETDIRNLRKLNHPNIIS 463

Query: 65  LKEVIRENDHLYFVFEYMK-ENLYQLMKDRNKLFPESVIRNIMYQILQGLAFIHKHGFFH 123
            K V  +      + EY     LY++++D  K  P +++ +   QI  G+ ++H H   H
Sbjct: 464 FKGVCTQAPCYCIIMEYCPYGQLYEVLRD-GKEIPPALVLDWSKQIASGMNYLHSHKIIH 640

Query: 124 RDMKPENLLCMGPELVKIADFG 145
           RD+K  N+L    ++VKI+DFG
Sbjct: 641 RDLKSPNVLVAKNDVVKISDFG 706
>03294
          Length = 1684

 Score = 79.7 bits (195), Expect = 3e-15,   Method: Compositional matrix adjust.
 Identities = 37/105 (35%), Positives = 62/105 (59%)
 Frame = -1

Query: 180  PIDVWAVGSIMAELYTFRPLFPGTSEVDEIFKICQVLGTPKKSDWPEGYQLASSMNFRFP 239
            P+DVW++G+I A++    P+F G SE+D++FKI +++GTP +  WPE ++L  + N  FP
Sbjct: 1675 PVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIFRIIGTPTEQTWPEFHKLP-AFNGMFP 1499

Query: 240  QCIPINLKTLIPNASSEAIQLMTEMLNWDPKKRPTASQALKHPYF 284
                  L   + +  S  + L+   L  DP +R +  + L+H YF
Sbjct: 1498 LWKEGKLSETLTDLDSLGLDLIERTLKCDPAQRISCKKMLQHAYF 1364
>15910
          Length = 1361

 Score = 77.8 bits (190), Expect = 1e-14,   Method: Compositional matrix adjust.
 Identities = 58/182 (31%), Positives = 88/182 (48%), Gaps = 4/182 (2%)
 Frame = +2

Query: 108 QILQGLAFIHKHGFFHRDMKPENLL--CMGPE-LVKIADFGLARELRSQPPYTDYVSTRW 164
            IL G+ +IH +G  HRD+KPENLL  CM  +  +K+ADFGL+R +  +   +    T  
Sbjct: 488 DILHGVQYIHANGVVHRDLKPENLLYECMTDDSKLKLADFGLSRIIEPEVQMSTVCGTPG 667

Query: 165 YRAPEVLLRSSVYSSPIDVWAVGSIMAELYT-FRPLFPGTSEVDEIFKICQVLGTPKKSD 223
           Y APEV L+   Y+  +D+W+VG I   L   + P F   +E +   KI +      +  
Sbjct: 668 YCAPEV-LKGDKYTPSVDMWSVGVIAYILLCGYEPFF-AENEFEMYRKIIKGEYKFDEEY 841

Query: 224 WPEGYQLASSMNFRFPQCIPINLKTLIPNASSEAIQLMTEMLNWDPKKRPTASQALKHPY 283
           W E                           S  A  ++ ++L  DPKKR TA++AL+ P+
Sbjct: 842 WSE--------------------------ISENAKDVVRKLLVIDPKKRLTATEALRLPW 943

Query: 284 FQ 285
            +
Sbjct: 944 VK 949
>18287
          Length = 678

 Score = 77.0 bits (188), Expect = 2e-14,   Method: Compositional matrix adjust.
 Identities = 43/115 (37%), Positives = 65/115 (56%), Gaps = 2/115 (1%)
 Frame = -3

Query: 177 YSSPIDVWAVGSIMAELYTFRPLFPGTSEVDEIFKICQVLGTPKKSDWPEGYQLASS--M 234
           Y   ID+W+VG I AEL + R LF     V ++  I  ++GTP+  D     + A +  +
Sbjct: 673 YDYSIDIWSVGCIFAELLSRRILFQAQGPVQQLDMIINLVGTPRPEDMERACEGARNHIL 494

Query: 235 NFRFPQCIPINLKTLIPNASSEAIQLMTEMLNWDPKKRPTASQALKHPYFQVGQV 289
           N  F +   + L  L P+A+ EA++L+T ML  +PK R +A +AL HPY   G+V
Sbjct: 493 NQPFRRQNLLTLYNLSPHATHEAVRLLTRMLILNPKNRISAEEALSHPYLDEGRV 329
>23319
          Length = 2235

 Score = 75.1 bits (183), Expect = 9e-14,   Method: Compositional matrix adjust.
 Identities = 43/114 (37%), Positives = 67/114 (58%), Gaps = 3/114 (2%)
 Frame = +3

Query: 174 SSVYSSPIDVWAVGSIMAELYTF-RPLFPGTSEVDEIFKICQVLGTPKKSDWPEGYQLAS 232
           + +YS+ ID+W+ G I AEL    RPLFPG  + D++ +I ++LGTP +  WP   QL  
Sbjct: 18  AKMYSTSIDMWSAGCIFAELANAGRPLFPGNDDDDQLKRIFKLLGTPTEDQWPGMTQLP- 194

Query: 233 SMNFR-FPQC-IPINLKTLIPNASSEAIQLMTEMLNWDPKKRPTASQALKHPYF 284
             N+R FP   +    + ++P  +S+   L+  +L   P  R +A +AL+HPYF
Sbjct: 195 --NYRMFPMYHVTTTWQQVVPKLNSKGRDLLQCLLVCCPSDRMSADEALQHPYF 350
>09606
          Length = 1300

 Score = 73.6 bits (179), Expect = 3e-13,   Method: Compositional matrix adjust.
 Identities = 74/317 (23%), Positives = 129/317 (40%), Gaps = 30/317 (9%)
 Frame = -3

Query: 1    MNRYTTMKQLGDGTYGSVLMGKSNESGELVAI---KRMKRKFYSWDECMNLREVKSLKKL 57
            M  +   ++LG G +  +  G+   +   VAI   ++ KR      E  N   V+    +
Sbjct: 1118 MENFVLYEELGKGEHSIIYKGRRKGTINFVAIHCIEKCKRP-----EVTN--TVRMTHDI 960

Query: 58   NHANVIKLKEVIRENDHLYFVFEYMKENLYQLMKDRNKLFPESVIRNIMYQILQGLAFIH 117
            +H NV++  E    ++HL+ V E         +  ++   PE+ IR+    ++ GL +IH
Sbjct: 959  SHPNVVQFHEWYETSNHLWLVVELCTGGSLADILAQDHHLPETSIRDFGIHLVTGLHYIH 780

Query: 118  KHGFFHRDMKPENLLCMGPELVKIADFGL--------------------------ARELR 151
              G    D++P  +L     ++K ADFGL                          A E+ 
Sbjct: 779  SLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEAGDQWNIQSAEEMM 600

Query: 152  SQPPYTDYVSTRWYRAPEVLLRSSVYSSPIDVWAVGSIMAELYTFRPLFPGTSEVDEIFK 211
             Q P +    +  Y APEV  + +  S   D+WA+G +  E+++  P F G     E + 
Sbjct: 599  KQVPTS---GSPTYMAPEV-FQGAEPSIMSDLWALGCVFYEMFSGHPPFLG-----ETYD 447

Query: 212  ICQVLGTPKKSDWPEGYQLASSMNFRFPQCIP-INLKTLIPNASSEAIQLMTEMLNWDPK 270
            I +                   +N  FP  +P +    L    S E + L+  +L  D  
Sbjct: 446  ITK----------------DKVLNKEFP--LPKVKGSRLSAKPSPEFLNLLESLLQKDST 321

Query: 271  KRPTASQALKHPYFQVG 287
            +R + +  +KH ++Q G
Sbjct: 320  RRLSWASLVKHAFWQGG 270
>01718
          Length = 959

 Score = 73.2 bits (178), Expect = 3e-13,   Method: Compositional matrix adjust.
 Identities = 67/283 (23%), Positives = 126/283 (44%), Gaps = 10/283 (3%)
 Frame = +3

Query: 8   KQLGDGTYGSVLMGKSNESGELVAIKRMKRKFYSWDECMNLREVKSLKKLNHANVIKLKE 67
           +++G G +  V       +G+++A   +K    + +    LREV+ L +L HAN+++   
Sbjct: 165 EKIGAGFFSEVFKVTHRITGQVMA---LKMNTMTSNRHNMLREVQLLNRLQHANILRFMG 335

Query: 68  VIRENDHLYFVFEYMKE-NLYQLMKDRNKLFPESVIRNIMYQILQGLAFIHKHGFFHRDM 126
           V      L+ + EY+   NL QL++ +++  P +    +   + +GL ++H   F HRD+
Sbjct: 336 VCVHEGQLHALTEYIPSGNLEQLLEKKDEELPWTQRIQLTLGLARGLDYLHSTRFIHRDL 515

Query: 127 KPENLLCMGPE----LVKIADFGLAREL-----RSQPPYTDYVSTRWYRAPEVLLRSSVY 177
             +N+L    +       IADFGLA ++     + + P    V + ++ APEV L    Y
Sbjct: 516 TSKNILIRREDNHGYHAVIADFGLATKIPDPLDKEKLP---TVGSPYWMAPEV-LNGHFY 683

Query: 178 SSPIDVWAVGSIMAELYTFRPLFPGTSEVDEIFKICQVLGTPKKSDWPEGYQLASSMNFR 237
           +   D+++VG IM E+    P  P                 P+ +++   Y         
Sbjct: 684 NERADLFSVGIIMCEITARIPADPDI--------------MPRMNNFGVDY--------- 794

Query: 238 FPQCIPINLKTLIPNASSEAIQLMTEMLNWDPKKRPTASQALK 280
                 + L  +I     + +QL  +    DP+KRP   + ++
Sbjct: 795 ------VALSEMISYCPLDYLQLAFKCCQVDPQKRPRGVEIIE 905
>13212
          Length = 1067

 Score = 72.0 bits (175), Expect = 7e-13,   Method: Compositional matrix adjust.
 Identities = 54/218 (24%), Positives = 95/218 (43%), Gaps = 9/218 (4%)
 Frame = -1

Query: 86   LYQLMKDRNKLFPESVIRNIMYQILQGLAFIHKHGFFHRDMKPENLLCMGPELVKIADFG 145
            L  +M D  K   E+ I  + +++   L F+H+H   HRD+K  N+L      VK+ADFG
Sbjct: 1022 LDSIMVDLEKPMTEAQICYVCHEMCMALDFLHRHHVIHRDIKAGNVLLTIDGEVKLADFG 843

Query: 146  L-ARELRSQPPYTDYVSTRWYRAPEVLLRSSVYSSP----IDVWAVGSIMAELYTFRPLF 200
            + A+  ++Q     ++ T ++ APEV+L  ++  +P     D+W++G  + E     P  
Sbjct: 842  VSAKNTQTQQKRDTFIGTPYWMAPEVVLCETLKDTPYDFKADIWSLGVTLIEFAQIEPPN 663

Query: 201  PGTSEVDEIFKICQ----VLGTPKKSDWPEGYQLASSMNFRFPQCIPINLKTLIPNASSE 256
                 +  + KI +     L  PKK  W + ++                           
Sbjct: 662  KEMHPMRVLIKIHKSDPPTLEKPKK--WTKLFK--------------------------- 570

Query: 257  AIQLMTEMLNWDPKKRPTASQALKHPYFQVGQVLGSSA 294
                + + L  DP  RPTA++ L+HP+ +       +A
Sbjct: 569  --DFIAKCLVKDPNLRPTAAELLEHPFMKRATATDKAA 462
>32359
          Length = 928

 Score = 63.9 bits (154), Expect(2) = 3e-12,   Method: Compositional matrix adjust.
 Identities = 40/123 (32%), Positives = 68/123 (55%), Gaps = 9/123 (7%)
 Frame = -1

Query: 4   YTTMKQLGDGTYGSVLMGKSNESGELVAIKRMKRKFYSWDECMNLREVKSLKKLNHANVI 63
           YT  K +G+G++G V   K  ++ ELVAIK++ +     D+    RE++ ++KL H N++
Sbjct: 424 YTDAKVIGNGSFGVVYQAKLVDTSELVAIKKVLQ-----DKRFKNRELQIMRKLEHQNIV 260

Query: 64  KLKEVI------RENDHLYFVFEYMKENLYQLMKDRNK---LFPESVIRNIMYQILQGLA 114
           KLK         ++   L  V EY+ E +Y++ +  +K     P   I+  MYQ+ + LA
Sbjct: 259 KLKFFFYSSGEKKDEVFLNLVLEYVPETVYRVARHYSKSKQTIPILYIKLYMYQLFRSLA 80

Query: 115 FIH 117
           +IH
Sbjct: 79  YIH 71

 Score = 25.4 bits (54), Expect(2) = 3e-12,   Method: Compositional matrix adjust.
 Identities = 11/18 (61%), Positives = 14/18 (77%)
 Frame = -3

Query: 120 GFFHRDMKPENLLCMGPE 137
           G  HRD+KP+NLL + PE
Sbjct: 65  GVCHRDIKPQNLL-LDPE 15
>09007
          Length = 1440

 Score = 68.2 bits (165), Expect = 9e-12,   Method: Compositional matrix adjust.
 Identities = 59/207 (28%), Positives = 99/207 (47%), Gaps = 16/207 (7%)
 Frame = -1

Query: 8   KQLGDGTYGSVLMGK-SNESGE--LVAIKRMKRKFYSWDECMNLREVKSLKKLNHANVIK 64
           K LG G +G+V     + ESGE   VA+K + +     D    L+E   ++ L+H N+++
Sbjct: 861 KSLGQGHFGTVRQAIWTAESGEKVQVAVKCLSKDKIHKDGQEFLKETAIMQMLDHENIVR 682

Query: 65  LKEVIREND-HLYFVFEYM-KENLYQLMKDRNKLFPESVIR--NIMYQILQGLAFIHKHG 120
           +  V+ +N   +  V E     +L + +K+ +     SV R  +   Q+  G++++    
Sbjct: 681 VYGVVMDNGADIMLVTELAPMRSLLECVKEVSARVDFSVPRLCDFSQQVCDGMSYLESKR 502

Query: 121 FFHRDMKPENLLCMGPELVKIADFGLARELRSQPPYTDYVST-------RWYRAPEVLLR 173
             HRD+   N+L      VKI+D G++  L +   Y     T        W  APE   R
Sbjct: 501 LVHRDLAARNILLFSKSKVKISDVGVSGALGAGKEYYQSQQTIHLQNAVAWC-APES-FR 328

Query: 174 SSVYSSPIDVWAVGSIMAELYT--FRP 198
           +  +SS  DVWA G ++ E +T  F+P
Sbjct: 327 NLCFSSASDVWAFGVLLWEFFTHGFQP 247
>17975
          Length = 449

 Score = 67.8 bits (164), Expect = 1e-11,   Method: Composition-based stats.
 Identities = 41/136 (30%), Positives = 70/136 (51%), Gaps = 3/136 (2%)
 Frame = +3

Query: 15  YGSVLMGKSNESGELVAIKRM-KRKFYSWDECMNLREVKSLKKLNHANVIKLKEVIREND 73
           +  V + +   +GE VA+K + K K          +EV+ +K + H NV++L EVI    
Sbjct: 6   FAVVKLARHVFTGEKVAVKVIDKTKLDEVSRSHLFQEVRCMKLVQHPNVVRLYEVIDTQT 185

Query: 74  HLYFVFEYMKE-NLYQLMKDRNKLFPESVIRNIMYQILQGLAFIHKHGFFHRDMKPENLL 132
            LY + E     ++Y  +   +    E + +    QI++ +++ HK    HRD+KPEN++
Sbjct: 186 KLYLILELGDGGDMYDYIMRHSGGLEEKLAKRYFRQIVEAISYCHKLHVVHRDLKPENVV 365

Query: 133 CM-GPELVKIADFGLA 147
               P LVK+ DFG +
Sbjct: 366 FFEKPGLVKLTDFGFS 413
>14477
          Length = 493

 Score = 67.8 bits (164), Expect = 1e-11,   Method: Composition-based stats.
 Identities = 43/153 (28%), Positives = 79/153 (51%), Gaps = 5/153 (3%)
 Frame = -1

Query: 9   QLGDGTYGSVLMG--KSNESGELVAIKRMKRKFYSWDECMN---LREVKSLKKLNHANVI 63
           +LG G +GSV+ G  + ++    VAIK +K      D  +    ++E + +KK++H +++
Sbjct: 469 KLGAGNFGSVMKGVCRLDDREIPVAIKVLKNA--DLDPSVQSELIKEAEVMKKMDHMHIV 296

Query: 64  KLKEVIRENDHLYFVFEYMKENLYQLMKDRNKLFPESVIRNIMYQILQGLAFIHKHGFFH 123
           +L  +  E + +  V E  K         +NK  P   I  +M+Q+ QG+ ++  + F H
Sbjct: 295 RLIGLC-EGETMMLVLELAKLGPLNKFLPKNKHLPLWNILELMWQVSQGMEYLEANKFVH 119

Query: 124 RDMKPENLLCMGPELVKIADFGLARELRSQPPY 156
           RD+   N+L       KI+DFG+++ L  +  Y
Sbjct: 118 RDLAARNILLCDEHFAKISDFGMSKTLSRENNY 20
>31489
          Length = 329

 Score = 67.0 bits (162), Expect = 2e-11,   Method: Composition-based stats.
 Identities = 33/90 (36%), Positives = 53/90 (58%), Gaps = 6/90 (6%)
 Frame = +3

Query: 51  VKSLKKLNHANVIKLKEVIRENDH------LYFVFEYMKENLYQLMKDRNKLFPESVIRN 104
           +K LK   H N+I ++E+++  D       ++ VF+ M+ +L++++     L  E  IR 
Sbjct: 3   IKILKHFKHDNIISIREILKPKDSYHDFKDIHVVFDLMESDLHRIIYSDQPLTEEH-IRY 179

Query: 105 IMYQILQGLAFIHKHGFFHRDMKPENLLCM 134
            +YQIL+GL +IH     HRD+KP NLL M
Sbjct: 180 FLYQILRGLKYIHSANVVHRDLKPSNLLSM 269
>00392
          Length = 668

 Score = 66.6 bits (161), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 50/170 (29%), Positives = 81/170 (47%), Gaps = 8/170 (4%)
 Frame = +3

Query: 50  EVKSLKKLNHANVIKLKEVIRENDH-----LYFVFEYMKENLYQLMKDRNKLFPESVIRN 104
           E + LK+L H N+++  +   E++H     +  V E M     +    R K     +++N
Sbjct: 81  EAEMLKELQHPNIVRFFDYWEEHNHRNRKVIILVTELMTSGTLKTYLKRFKKPNVKILKN 260

Query: 105 IMYQILQGLAFIHKHG--FFHRDMKPENLLCMGPE-LVKIADFGLARELRSQPPYTDYVS 161
              Q+L+GL F+H       HRD+K +N+   GP   VKI D GLA  L++Q      + 
Sbjct: 261 WCRQVLKGLYFLHTRTPPVIHRDLKCDNIFITGPTGSVKIGDLGLAT-LKNQSFAKSVIG 437

Query: 162 TRWYRAPEVLLRSSVYSSPIDVWAVGSIMAELYTFRPLFPGTSEVDEIFK 211
           T  + APE  +    Y   +DV+A G  M E+ +    +   S   +I+K
Sbjct: 438 TPEFMAPE--MYEEHYDEAVDVYAFGMCMLEMASSEYPYSECSNAAQIYK 581
>18484
          Length = 635

 Score = 66.6 bits (161), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 41/115 (35%), Positives = 61/115 (53%), Gaps = 1/115 (0%)
 Frame = +1

Query: 97  FPESVIRNIMYQILQGLAFIHKHGFFHRDMKPENLLCMGPELVKIADFGLARELRSQPPY 156
           F E V      +I  GL F+H  G  +RD+K +N++      +KIADFG+ +E  +    
Sbjct: 34  FKEPVAAFYAAEIAVGLFFLHDQGIIYRDLKLDNVMLDSEGHIKIADFGMCKEGMTGDAT 213

Query: 157 T-DYVSTRWYRAPEVLLRSSVYSSPIDVWAVGSIMAELYTFRPLFPGTSEVDEIF 210
           T  +  T  Y APE++L    YS  +D WA G ++ E+   +P F G  E DE+F
Sbjct: 214 TRTFCGTPDYIAPEIVLYQP-YSKSVDWWAYGVLLFEMLAGQPPFDGEDE-DELF 372
>30755
          Length = 1137

 Score = 65.1 bits (157), Expect = 9e-11,   Method: Compositional matrix adjust.
 Identities = 54/198 (27%), Positives = 84/198 (42%), Gaps = 7/198 (3%)
 Frame = +2

Query: 94  NKLFPESVIRNIMYQILQGLAFIHKHGFFHRDMKPENLLCMGPELVKIADFGLARELRSQ 153
            ++F E   R    +I+  L ++H  G  +RD+K ENLL      +K+ADFGL +E  + 
Sbjct: 14  ERIFTEERTRFYGAEIISALGYLHSQGIIYRDLKLENLLLDKDGHIKVADFGLCKEDITY 193

Query: 154 PPYTD-YVSTRWYRAPEVLLRSSVYSSPIDVWAVGSIMAELYTFR-PLFPGTSEVDEIFK 211
              T  +  T  Y APEV L  + Y   +D W  G +M E+   R P +    + D +F 
Sbjct: 194 GRTTKTFCGTPEYLAPEV-LDDNDYGRAVDWWGTGVVMYEMICGRLPFY--NRDHDVLFT 364

Query: 212 ICQVLGTPKKSDWPEGYQLASSMNFRFPQCIPINLKTLIPNASSEAIQLMTEMLNWDPKK 271
           +  V                   + +FP+           N + EA  L++ +L  DP+ 
Sbjct: 365 LILV------------------EDVKFPR-----------NITDEAKSLLSGLLAKDPRN 457

Query: 272 RPTASQ-----ALKHPYF 284
           R    Q        HP+F
Sbjct: 458 RLGGGQDDVKEIQAHPFF 511
>01392
          Length = 1806

 Score = 64.7 bits (156), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 57/199 (28%), Positives = 84/199 (42%), Gaps = 19/199 (9%)
 Frame = -1

Query: 105  IMYQILQGLAFIHKHGFFHRDMKPENLLCMGPEL---VKIADFGLARELRSQ------PP 155
            ++  I + L F+H  G  HRD+KPEN+LC   +    VKI DF LA  +         P 
Sbjct: 1776 VVRHIARALDFLHSKGIAHRDLKPENILCEHLDDVVPVKICDFDLASGISCDGDGTKTPE 1597

Query: 156  YTDYVSTRWYRAPEVLLR----SSVYSSPIDVWAVGSIMAELYTFRPLFPGTSEVD---- 207
                V +  Y APEV+      S  Y    D+W++G I+  +    P F G    D    
Sbjct: 1596 LLTPVGSAEYMAPEVVDAWVGDSFSYDKRCDLWSLGIILYIMLCGYPPFYGQCGEDCGWN 1417

Query: 208  --EIFKICQVLGTPKKSDWPEGYQLASSMNFRFPQCIPINLKTLIPNASSEAIQLMTEML 265
              E    CQ +      D           +++FP            + SS A  L+  +L
Sbjct: 1416 RGEACHDCQDMLFNSIQDG----------HYKFP-------SQEWTSISSSAKDLIRHLL 1288

Query: 266  NWDPKKRPTASQALKHPYF 284
              +P+KR +A+  LKHP+ 
Sbjct: 1287 VREPRKRYSAADVLKHPWI 1231
>14420
          Length = 528

 Score = 64.3 bits (155), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 39/153 (25%), Positives = 76/153 (49%), Gaps = 2/153 (1%)
 Frame = +2

Query: 48  LREVKSLKKLNHANVIKLKEVIRENDHLYFVFEYMKE-NLYQLMKDRNKLFPESVIRNIM 106
           + E+  +++  + N++   +     + L+ V E++   +L  ++ +      E  I  + 
Sbjct: 44  INEILVMRENQNPNIVNYLDSYLVGEELWVVMEFLAGGSLTDVVTE--TCMDEGQIAAVC 217

Query: 107 YQILQGLAFIHKHGFFHRDMKPENLLCMGPELVKIADFGLARELR-SQPPYTDYVSTRWY 165
            + LQ L F+H++   HRD+K +N+L      VK+ DFG   +L   Q   +  V T ++
Sbjct: 218 RECLQALEFLHENQVIHRDIKSDNILLGMDGSVKLTDFGFCAQLSPEQSKRSTMVGTPYW 397

Query: 166 RAPEVLLRSSVYSSPIDVWAVGSIMAELYTFRP 198
            APEV+ R   Y   +D+W++G +  E+    P
Sbjct: 398 MAPEVVTRKQ-YGPTVDIWSLGVMCIEMIEGEP 493
>19761
          Length = 473

 Score = 63.5 bits (153), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 39/127 (30%), Positives = 66/127 (51%), Gaps = 3/127 (2%)
 Frame = -3

Query: 97  FPESVIRNIMYQILQGLAFIHKHG--FFHRDMKPENLLCMGPELVKIADFGLARELRSQP 154
            PE +I   + Q    L ++H H     HRD+KP+N+       V++ D GLAR+L    
Sbjct: 432 LPERLIVCWLMQTASALNYMHTHTPVILHRDLKPQNIYVTEKGDVRLGDLGLARKLTGPA 253

Query: 155 PY-TDYVSTRWYRAPEVLLRSSVYSSPIDVWAVGSIMAELYTFRPLFPGTSEVDEIFKIC 213
            + T  V T  Y +PE+L +   Y+S  D+W++G +  ++   +    G+ E+  +F + 
Sbjct: 252 DFATSQVGTIMYLSPEILSQQP-YNSKSDIWSLGCVFYDITGKK----GSDEMGVMFLLV 88

Query: 214 QVLGTPK 220
           QV+G  K
Sbjct: 87  QVMGGRK 67
>12453
          Length = 680

 Score = 62.4 bits (150), Expect = 5e-10,   Method: Compositional matrix adjust.
 Identities = 36/113 (31%), Positives = 55/113 (48%)
 Frame = +3

Query: 185 AVGSIMAELYTFRPLFPGTSEVDEIFKICQVLGTPKKSDWPEGYQLASSMNFRFPQCIPI 244
            VG I  E+   RPLFPG++  DE+  I + LGTP +   P   +    +    P     
Sbjct: 3   GVGCIFYEMACGRPLFPGSTVEDELHLIFKTLGTPTEDSLPSISRNPDFLALNLPHYQGE 182

Query: 245 NLKTLIPNASSEAIQLMTEMLNWDPKKRPTASQALKHPYFQVGQVLGSSAHHL 297
            L T+ P   S+ + L+ + L ++ K R +A+ +LKH +F     LG   H L
Sbjct: 183 ALITIAPRLDSDGLDLLAKFLKYNAKIRVSAADSLKHSFF---NSLGPGVHML 332
>19094
          Length = 898

 Score = 62.0 bits (149), Expect = 7e-10,   Method: Compositional matrix adjust.
 Identities = 35/107 (32%), Positives = 56/107 (52%), Gaps = 1/107 (0%)
 Frame = +1

Query: 88  QLMKDRNKLFPESVIRNIMYQILQGLAFIHKHGFFHRDMKPENLLCMGPELVKIADFGLA 147
            +M+ RNK   E  I  I+Y  L+GL ++H     HRD+K  N+L       K+ADFG+A
Sbjct: 22  DIMRLRNKTLVEREIATILYYTLKGL*YLHSRRKIHRDIKAGNILLNNEGHAKLADFGVA 201

Query: 148 RELR-SQPPYTDYVSTRWYRAPEVLLRSSVYSSPIDVWAVGSIMAEL 193
            +L  +       + T ++ APEV ++   Y    D+W++G    E+
Sbjct: 202 GQLTDTMAKRNTVIGTPYWMAPEV-IQEIGYDCVADIWSLGITALEM 339
>26560
          Length = 398

 Score = 61.6 bits (148), Expect = 8e-10,   Method: Compositional matrix adjust.
 Identities = 36/121 (29%), Positives = 62/121 (51%), Gaps = 4/121 (3%)
 Frame = -1

Query: 93  RNKLFPESVIRNIMYQILQGLAFIHKHGFFHRDMKPENLLCMGPELVKIADFGLARELRS 152
           ++ +F E  +R    +++ GL  +H     +RD+KP N+L      V+I+D GLA +   
Sbjct: 377 QHGVFTEKEVRFYAAEVMLGLEHMHSRFVVYRDLKPANILLDENGHVRISDLGLACDFSK 198

Query: 153 QPPYTDYVSTRWYRAPEVLLRSSVYSSPIDVWAVGSIMAELYT----FRPLFPGTSEVDE 208
           + P+   V T  Y APEVL++   Y S  D ++ G ++ +L      FR    G + +D 
Sbjct: 197 KRPHAS-VGTHGYMAPEVLMKGQSYDSSADWFSFGCMLYKLLKGHSPFRQHNQGQARIDR 21

Query: 209 I 209
           +
Sbjct: 20  M 18
>18401
          Length = 463

 Score = 61.6 bits (148), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 44/140 (31%), Positives = 66/140 (47%), Gaps = 15/140 (10%)
 Frame = -3

Query: 160 VSTRWYRAPEVLLRSSVYSSPIDVWAVGSIMAELYTFRPLFPGTSEVDEIFKICQVLGT- 218
           VSTR YRAPEV+L    +S P DVW+VG IM ELYT   LF      + +  + ++LG+ 
Sbjct: 449 VSTRHYRAPEVILELG-WSHPCDVWSVGCIMFELYTGYTLFQTHDNKEHLAMMERILGSL 273

Query: 219 -------PKKSDWPEGYQLASSMNFRFPQCIPINLKTLIPNASS-------EAIQLMTEM 264
                   KK  +    +L         + +  N K L+            +   LM ++
Sbjct: 272 PYRMAKKTKKQKYFHHGRLDVPERSSMARYVRENTKPLLRYVKDRENKDHQQLFDLMKKL 93

Query: 265 LNWDPKKRPTASQALKHPYF 284
           L ++   R +  QAL+HP+F
Sbjct: 92  LAYEASSRYSLLQALQHPFF 33
>27546
          Length = 426

 Score = 61.2 bits (147), Expect = 1e-09,   Method: Composition-based stats.
 Identities = 32/105 (30%), Positives = 57/105 (54%), Gaps = 2/105 (1%)
 Frame = -1

Query: 49  REVKSLKKLNHANVIKLKEVIRENDHLYFVFEYMKENLYQLMKDRNKLFP--ESVIRNIM 106
           RE++ L +L+H N+I++  +++    ++    Y ++    ++    K  P  E+  +   
Sbjct: 333 RELEILTRLDHPNIIQIHSILQRGPKIFIFMRYAEKG--DMLSHIKKTGPIDEAQTKVWF 160

Query: 107 YQILQGLAFIHKHGFFHRDMKPENLLCMGPELVKIADFGLARELR 151
           +Q+ + L ++H H   HRD+K EN+L      VKIADFG AR  R
Sbjct: 159 FQMAKALQYLHSHDIAHRDLKCENILLSKRLNVKIADFGFARYCR 25
>27405
          Length = 532

 Score = 61.2 bits (147), Expect = 1e-09,   Method: Composition-based stats.
 Identities = 43/174 (24%), Positives = 80/174 (45%), Gaps = 6/174 (3%)
 Frame = -3

Query: 15  YGSVLMGKSNESGELVAIKRMKRKFYSWDE----CMNLREVKSLKKLNHAN--VIKLKEV 68
           +G V   +  ++G++ A+K + +K           +N R + SL      +  ++ +   
Sbjct: 527 FGEVYGCRKADTGKMYAMKCLDKKRIKMKGGETLALNERIMLSLVSTGEGSPFIVCMTYA 348

Query: 69  IRENDHLYFVFEYMKENLYQLMKDRNKLFPESVIRNIMYQILQGLAFIHKHGFFHRDMKP 128
            +  + L F+ + M          ++ +F E  +R    +++ GL  +H     +RD+KP
Sbjct: 347 FQTPEKLCFILDLMNGGDLHYHLSQHGVFTEKEVRFYAAEVMLGLEHMHSRFVVYRDLKP 168

Query: 129 ENLLCMGPELVKIADFGLARELRSQPPYTDYVSTRWYRAPEVLLRSSVYSSPID 182
            N+L      V+I+D GLA +   + P+   V T  Y APEVL++   Y S  D
Sbjct: 167 ANILLDENGHVRISDLGLACDFSKKKPHAS-VGTHGYMAPEVLMKGQAYDSSAD 9
>14116
          Length = 1017

 Score = 58.5 bits (140), Expect = 8e-09,   Method: Compositional matrix adjust.
 Identities = 62/211 (29%), Positives = 104/211 (49%), Gaps = 18/211 (8%)
 Frame = -1

Query: 3   RYTTM-KQLGDGTYGSV---LMGKSNESGE-LVAIKRMKRKFYSWDECMN-LREVKSLKK 56
            + TM +++G G +G V    +    + G+ LVA+K +        E  + L+E   +K 
Sbjct: 636 EFLTMGEEIGKGNFGCVKRGFLTLPEQKGDILVAVKTLHNNNPREIELQSFLQEALIMKD 457

Query: 57  LNHANVIKLKEVIRENDHL-YFVFEYMKE-NLYQLMKDRNKLFPESVIRN-IMY--QILQ 111
            +H+NV+ L  +    D +   V  +MK  +L   ++D      +  I++ IMY   I +
Sbjct: 456 FHHSNVLTLIGICLNLDDMPLVVLPFMKHGDLLTYIRDDQH---QPTIKDLIMYGVDIAR 286

Query: 112 GLAFIHKHGFFHRDMKPENLLCMGPE--LVKIADFGLARELRSQPPYTDY-----VSTRW 164
           G+ ++    F HRD+   N  CM  E   VK+ADFGLAR++  +  Y+       +  +W
Sbjct: 285 GMDYLAGLKFVHRDLAARN--CMLDEDFHVKVADFGLARDIYEKEYYSSENKKAKLPVKW 112

Query: 165 YRAPEVLLRSSVYSSPIDVWAVGSIMAELYT 195
             A E L + + Y S  DVW+ G ++ EL T
Sbjct: 111 -MALESLEKGN-YDSKTDVWSYGVVLWELLT 25
>20559
          Length = 430

 Score = 58.2 bits (139), Expect = 1e-08,   Method: Composition-based stats.
 Identities = 30/82 (36%), Positives = 51/82 (62%), Gaps = 3/82 (3%)
 Frame = -2

Query: 1   MNRYTTMKQLGDGTYGSVLMGKSNESGELVAIKRMKRKFYSWDECM---NLREVKSLKKL 57
           M +Y  ++++G+GTYG+V   K+ E+ E+VA+KR+  +    DE +    LRE+  LK+L
Sbjct: 378 MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRV--RLDDDDEGVPSSALREICLLKEL 205

Query: 58  NHANVIKLKEVIRENDHLYFVF 79
            H N+++L +V+     L  VF
Sbjct: 204 KHRNIVRLHDVLHSERKLTLVF 139
>07940
          Length = 1336

 Score = 57.4 bits (137), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 34/104 (32%), Positives = 54/104 (51%), Gaps = 3/104 (2%)
 Frame = -3

Query: 96  LFPESVIRNIMYQILQGLAFIHKHGFFHRDMKPENLLCMGPELVKIADFGLARELRSQPP 155
           L P+ +I +  YQ+ +G+ ++      HRD+   N+L     ++KIADFGL R L+    
Sbjct: 356 LTPKDLI-SYAYQVARGMEYLASKQCIHRDLAARNVLVAEEYVLKIADFGLTRNLQQFDY 180

Query: 156 YTDYVSTRW---YRAPEVLLRSSVYSSPIDVWAVGSIMAELYTF 196
           Y      R    + APE L     Y+S  DVW+ G ++ E++T 
Sbjct: 179 YRKTTDGRLPVKWMAPEALFDRK-YTSKSDVWSYGVLLWEIFTL 51
>20640
          Length = 1492

 Score = 57.4 bits (137), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 42/131 (32%), Positives = 63/131 (48%), Gaps = 7/131 (5%)
 Frame = +1

Query: 120 GFFHRDMKPENLLCMGPELVKIADFGLARELRSQPPYT----DYVSTRWYRAPEVLLRSS 175
           G+ HRD+   N L     +VKI+DFGLAR + S   Y     D +  RW     +L    
Sbjct: 4   GYVHRDLATRNCLVGHDLVVKISDFGLARSVHSVDYYRGSEHDAIPIRWMPLEAILYNK- 180

Query: 176 VYSSPIDVWAVGSIMAELYTF--RPLFPGT-SEVDEIFKICQVLGTPKKSDWPEGYQLAS 232
            +S+  DVW+ G ++ E++ F  +P +  T  EV    K  +VL  P+++  P  Y+L  
Sbjct: 181 -FSTQSDVWSFGVVLWEIFAFALQPYYGLTHEEVVRFVKEGKVLACPERTP-PPMYELMK 354

Query: 233 SMNFRFPQCIP 243
               R P   P
Sbjct: 355 QCWHRRPATRP 387
>31885
          Length = 529

 Score = 57.4 bits (137), Expect = 2e-08,   Method: Composition-based stats.
 Identities = 39/154 (25%), Positives = 67/154 (43%), Gaps = 4/154 (2%)
 Frame = -2

Query: 51  VKSLKKLNHANVIKLKEVIRENDHLYFVFEYMKENLYQLMKDRNKLFPESVIRNIMYQIL 110
           V  L +L+H  ++ L    ++ + L+ V +       +    +   F E  ++  + Q+ 
Sbjct: 519 VDMLTRLDHPFLVNLWYAFQDEEDLFMVVDLFLGGDLRYHMQQEVSFREDCVKFYLCQLA 340

Query: 111 QGLAFIHKHGFFHRDMKPENLLCMGPELVKIADFGLARELRSQPPYTDYVSTRWYRAPEV 170
             L ++      HRD+KP+N+L        + DF +A +L      T    TR Y APEV
Sbjct: 339 LVLDYLRSQKIVHRDIKPDNILLDEQGHCHVTDFNIATQLEDDELATSTSGTRPYMAPEV 160

Query: 171 ----LLRSSVYSSPIDVWAVGSIMAELYTFRPLF 200
               +     Y  P+D W++G  + EL   R  F
Sbjct: 159 YGVAINERRGYGFPVDWWSLGVSLFELLKKRRPF 58
>26711
          Length = 405

 Score = 56.6 bits (135), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 38/111 (34%), Positives = 59/111 (53%), Gaps = 4/111 (3%)
 Frame = -2

Query: 105 IMYQILQGLAFIHKHGFFHRDMKPENLLCMGPEL--VKIADFGLARELRSQPPYTDYVS- 161
           ++ Q+L  L  +H  G  H D+KP NLL  G +L  V++ DFGLAR+L   PP   +++ 
Sbjct: 401 VVKQVLDILQHVHAQGVVHMDLKPSNLLLSGDKLDSVQLIDFGLARKLY--PPQETFLNH 228

Query: 162 -TRWYRAPEVLLRSSVYSSPIDVWAVGSIMAELYTFRPLFPGTSEVDEIFK 211
            T  + +PE L    + S+  DVW VG +   L + +  F   S  + + K
Sbjct: 227 GTPGFTSPEALDVKPI-STASDVWGVGVLAYILLSGQSPFQADSATESLKK 78
>00715
          Length = 1788

 Score = 53.9 bits (128), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 48/181 (26%), Positives = 76/181 (41%), Gaps = 30/181 (16%)
 Frame = +1

Query: 34  RMKRKFYSWDECMNLREVKSLKKLNHANVIKLKEVIRENDHLYFVFEYMKE-NLYQLMKD 92
           R  R+ YS +E +  R    L+ +N  +++    + R  D  +   EY+   NL  ++ D
Sbjct: 46  RALRQSYS-NELLAFR--CGLRHVNVVSILGATSLHRFEDGAWLAMEYVGPLNLQTILND 216

Query: 93  RNKLFPESVIRNIMYQILQGLAFIHKHGFFHRDMKPENLLCMGPELVKIADFGLAR---- 148
             +    S+  ++  Q+ +GL ++H     H D+KP N L      ++IADFG       
Sbjct: 217 HQQDIDSSMRLSLALQMARGLHYLHSINIVHLDLKPANCLLTRDLKLRIADFGCCHQLTP 396

Query: 149 ---------------ELRSQPPY----TDYVSTRWYRAPEVL------LRSSVYSSPIDV 183
                          EL   P       +   T  YRAPE+L      +RS VYS  I +
Sbjct: 397 TGLDMGEREGGMAGNELELTPVQGAWKNELAGTLAYRAPELLKGLQPSVRSDVYSLGITL 576

Query: 184 W 184
           W
Sbjct: 577 W 579
>11780
          Length = 1713

 Score = 53.9 bits (128), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 53/206 (25%), Positives = 92/206 (44%), Gaps = 14/206 (6%)
 Frame = +3

Query: 10  LGDGTYGSVLMGKSNESGELVAIKRMKRKFYSWDECMNLREVKSLKKLNHANVIKLKEVI 69
           +G G +G V  G     G+ VAIK++K K     E   L+E   +  L H N+++L  V+
Sbjct: 621 IGKGDFGDVYKGMYR--GQPVAIKQLKDK--DRGEQSFLQEASVMTSLRHDNLVRLIGVV 788

Query: 70  RENDHLYFVFEYM-KENLYQLMKDRNKLFPESVIR-----NIMYQILQGLAFIHKHGFFH 123
              + ++ V E+M K NL + ++ R +    SVI      N        + ++      H
Sbjct: 789 L-GETIFLVTEFMGKGNLVEYLRSRGR----SVITKKDQINFATDTCAAMEYLESKRLVH 953

Query: 124 RDMKPENLLCMGPELVKIADFGLARELRSQPPYTDYVST------RWYRAPEVLLRSSVY 177
           RD+   N+L       K++DFGLA+       + D+  T      +W  APE L  + ++
Sbjct: 954 RDLAARNVLVHDDGKAKVSDFGLAK-------FGDFSQTSVKFPIKW-TAPEALRENKIH 1109

Query: 178 --SSPIDVWAVGSIMAELYTFRPLFP 201
                +++W +  +M  L  +    P
Sbjct: 1110*QVRHVELWHI--VMGNLLLWSSALP 1181
>11404
          Length = 563

 Score = 53.5 bits (127), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 44/144 (30%), Positives = 70/144 (48%), Gaps = 12/144 (8%)
 Frame = +1

Query: 2   NRYTTMKQLGDGTYGSVLMGKSNESGELVAIKRMKRK--FYSWDECMNLREVKSLKKLNH 59
           +RY     +G G++G V+    +   E VAIK +K K  F +  +     EVK L+ +N 
Sbjct: 139 DRYEIDSLIGKGSFGQVVKAYDHTDNEQVAIKIIKNKKPFLNQAQI----EVKLLEMMNR 306

Query: 60  AN------VIKLKEVIRENDHLYFVFEYMKENLYQLMKDRN-KLFPESVIRNIMYQILQG 112
            +      +++LK       HL  VFE +  NLY L+++ N +    ++ R    Q+   
Sbjct: 307 HDTDNKYYIVRLKRHFMFRSHLCLVFELLSYNLYDLLRNTNFRGVSLNLTRKFAQQLCTA 486

Query: 113 LAFIH--KHGFFHRDMKPEN-LLC 133
           L F+   +    H D+KPEN LLC
Sbjct: 487 LLFLATPEMSIIHCDLKPENILLC 558
>21079
          Length = 878

 Score = 53.1 bits (126), Expect = 4e-07,   Method: Compositional matrix adjust.
 Identities = 35/134 (26%), Positives = 63/134 (47%), Gaps = 3/134 (2%)
 Frame = +1

Query: 59  HANVIKLKEVIRENDHLYFVFEYMKE-NLYQLMKDRNKLFPESVIRNIMYQILQGLAFIH 117
           H  ++ L +       +  V E++    L++ +   + +  E    + + QI  G+ ++H
Sbjct: 1   HPKLLMLWDAFEAPRTMVLVMEFVGAGELFERVIRDDFVLTERDCVHFVRQICSGVGYMH 180

Query: 118 KHGFFHRDMKPENLLCMG--PELVKIADFGLARELRSQPPYTDYVSTRWYRAPEVLLRSS 175
                H D+KPEN+LC+      +KI DFGLAR  +          T  + APEV+    
Sbjct: 181 TQSILHLDLKPENVLCVSDNSNQIKIIDFGLARFYKPGDSLQVLFGTPEFIAPEVVNYDE 360

Query: 176 VYSSPIDVWAVGSI 189
           + +   D+W++G I
Sbjct: 361 I-NFTTDMWSIGVI 399
>04852
          Length = 1462

 Score = 52.8 bits (125), Expect = 4e-07,   Method: Compositional matrix adjust.
 Identities = 47/187 (25%), Positives = 83/187 (44%), Gaps = 33/187 (17%)
 Frame = +1

Query: 43  DECMNLREVKSLKKL-NHANVIKLKEVIRENDHLYFVFEYMKE-NLYQLMKDRNK----- 95
           D    L+ +K++KK+ +H N++       +   L+ + E+ K  NL   ++         
Sbjct: 76  DFVQELQVMKAVKKMGSHINIVNFLGCCTQGGPLWVIVEFAKNGNLRDFLESCRDGINGY 255

Query: 96  ---LFPES-----------VIR--NIM---YQILQGLAFIHKHGFFHRDMKPENLLCMGP 136
              + P+            VIR  N++   +QI +G+ F+      HRD+   N+L    
Sbjct: 256 GKFVSPQDPGWYTKTPGGHVIRRKNLLSYAFQIARGMEFLASRKCIHRDLAARNVLVTEE 435

Query: 137 ELVKIADFGLARELRSQPPYTDYVSTRW-------YRAPEVLLRSSVYSSPIDVWAVGSI 189
            ++KIADFGL+R         DY   R        + APE L     Y++  DVW+ G +
Sbjct: 436 HVLKIADFGLSRT-------GDYYKKRSGGRLPVKWMAPEALFDMR-YTTKSDVWSFGVV 591

Query: 190 MAELYTF 196
           + E+++ 
Sbjct: 592 LWEIFSL 612
>16003
          Length = 926

 Score = 52.8 bits (125), Expect = 5e-07,   Method: Compositional matrix adjust.
 Identities = 32/87 (36%), Positives = 52/87 (59%)
 Frame = -1

Query: 198 PLFPGTSEVDEIFKICQVLGTPKKSDWPEGYQLASSMNFRFPQCIPINLKTLIPNASSEA 257
           P  PG +++D++ KI  +LGTP +++WP    L   + F+  Q  P  LK +   A  + 
Sbjct: 911 PFLPGDTDLDQLGKIFNMLGTPTETEWPAVTSLPDYIQFKHCQKQP--LKEIFTAAGDDL 738

Query: 258 IQLMTEMLNWDPKKRPTASQALKHPYF 284
           ++L+ ++L  +P  R TA+QALK PYF
Sbjct: 737 LELLDKLLAMNPLHRCTATQALKMPYF 657
>13066
          Length = 551

 Score = 52.4 bits (124), Expect = 5e-07,   Method: Compositional matrix adjust.
 Identities = 36/143 (25%), Positives = 61/143 (42%), Gaps = 4/143 (2%)
 Frame = +3

Query: 49  REVKSLKKLNHANVIKLKEVIRENDHLYFVFEYMKENLYQLMKDRNKLFPESVIRNIMYQ 108
           RE+  L KL+H  +I++  +++     +    + +               E   +   YQ
Sbjct: 123 RELDLLTKLDHPYIIQIHSILQRXPKNFIFMRFAERGDLLTYIQEVGFVKEKQAKIWFYQ 302

Query: 109 ILQGLAFIHKHGFFHRDMKPENLLCMGPELVKIADFGLAREL--RSQPPYTD--YVSTRW 164
           +   L ++H +   HRD+K EN+L      VK+ADFG A      S   Y    Y  +  
Sbjct: 303 MTTALNYLHSYDVAHRDLKCENILLSSHFNVKLADFGFACACITESGEKYMSRTYCGSAA 482

Query: 165 YRAPEVLLRSSVYSSPIDVWAVG 187
           Y APE++  +       D W++G
Sbjct: 483 YAAPEIVYGAPYAPKVADAWSLG 551
>17300
          Length = 480

 Score = 52.4 bits (124), Expect = 6e-07,   Method: Composition-based stats.
 Identities = 32/98 (32%), Positives = 50/98 (51%), Gaps = 8/98 (8%)
 Frame = +1

Query: 109 ILQGLAFIHKHGFFHRDMKPENLLCMGPELVKIADFGLARELRSQPPYTDY------VST 162
           I  G+  +   G+ HRD+   N+L     + K+ADFGL+RE+ S      Y      +  
Sbjct: 1   ISSGMGXLADMGYVHRDLAARNILVNEILVCKVADFGLSREIESDTTEGAYTTKGGKIPV 180

Query: 163 RWYRAPEVLLRSSVYSSPIDVWAVGSIMAELYTF--RP 198
           RW  APE +     ++S  DVW+ G +M E+ ++  RP
Sbjct: 181 RW-TAPEAIAYRK-FTSASDVWSFGVVMWEVMSYGERP 288
>36481
          Length = 806

 Score = 52.0 bits (123), Expect = 6e-07,   Method: Compositional matrix adjust.
 Identities = 36/129 (27%), Positives = 68/129 (52%), Gaps = 7/129 (5%)
 Frame = +2

Query: 11  GDGTYGSVLMGKSNESGELVAIKRMKRKFYSWDECMNLREVKSLKKLN----HAN--VIK 64
           G+GT+G V+  K    G+ +A+K +K     + E   L E+  L+KL     HA    ++
Sbjct: 389 GEGTFGKVVQCKDLLKGDDIALKIIK-NVDKYREAAKL-EINVLEKLREKDPHAKHMCVQ 562

Query: 65  LKEVIRENDHLYFVFEYMKENLYQLMKDRNK-LFPESVIRNIMYQILQGLAFIHKHGFFH 123
           + +    + H+   F  +  +++  +KD +   +P   +R+I YQ+   + F+H++   H
Sbjct: 563 MLDWFDYHGHVCISFHMLGLSVFDFLKDNSYGAYPIEQVRHISYQLCYAVNFLHENQLTH 742

Query: 124 RDMKPENLL 132
            D+KPEN+L
Sbjct: 743 TDLKPENIL 769
>01106
          Length = 878

 Score = 52.0 bits (123), Expect = 7e-07,   Method: Compositional matrix adjust.
 Identities = 43/149 (28%), Positives = 75/149 (50%), Gaps = 14/149 (9%)
 Frame = +3

Query: 3   RYTTMKQLGDGTYGSVLMGKSNESGELVAIKRMKRKFYSWDECMNLREVKSLKKLNHANV 62
           RY  +++LG G + +V +         VA+K +K   +  +  ++  EVK LK +  ++V
Sbjct: 321 RYHVIRKLGWGHFSTVWLCWDLTCKRFVALKVVKSAQHYTETALD--EVKLLKCVRESDV 494

Query: 63  I---KLKEVIREND---------HLYFVFEYMKENLYQLMKDRN-KLFPESVIRNIMYQI 109
               + K V   +D         H+  VFE +  NL +L+   N +  P   ++ I+ Q+
Sbjct: 495 ADPARAKCVQLLDDFKISGVNGTHVAMVFEVLGYNLLKLIIRSNYQGIPIHNVKLIIRQV 674

Query: 110 LQGLAFIH-KHGFFHRDMKPENLLCMGPE 137
           L+GL+++H K    H D+KPEN+L    E
Sbjct: 675 LEGLSYMHAKCRIIHTDIKPENILICVDE 761
>29360
          Length = 363

 Score = 52.0 bits (123), Expect = 8e-07,   Method: Composition-based stats.
 Identities = 37/114 (32%), Positives = 60/114 (52%), Gaps = 7/114 (6%)
 Frame = +3

Query: 26  SGELVAIKRMKRKFYSWDECMNLREVKSLKKLNHA-----NVIKLKEVIRENDHLYFVFE 80
           + E+VAIK +K    S+     + EV  L++L+       N ++  E  +  +H   VFE
Sbjct: 24  TSEIVAIKILKNH-PSYARQGQI-EVSILQRLSQESADDYNFVRAFECFQHKNHTCLVFE 197

Query: 81  YMKENLYQLMKDRNKL--FPESVIRNIMYQILQGLAFIHKHGFFHRDMKPENLL 132
            +++NLY  +K +NK    P   IR I  Q+L  L  + + G  H D+KPEN++
Sbjct: 198 MLEQNLYDFLK-QNKFQPLPLKYIRPITQQVLTALRKLKQLGLIHADLKPENIM 356
>24241
          Length = 413

 Score = 50.1 bits (118), Expect = 2e-06,   Method: Composition-based stats.
 Identities = 32/112 (28%), Positives = 66/112 (58%), Gaps = 3/112 (2%)
 Frame = -2

Query: 7   MKQLGDGTYGSVLMGKSNESGELVAIKRMK-RKFYSWDECMNLREVKSLKKLNHAN-VIK 64
           + ++G+GTYG V   +   +G  +A+K+++ R          +RE+  L++L H   ++ 
Sbjct: 328 LSKIGEGTYGVVYKCRHRATGRKLAMKKIRLRGSEDGVPSSAIREIAMLRELRHTQXLVC 149

Query: 65  LKEVIRENDHLYFVFEYMKENLYQLMKDRNKLFPESVIRN-IMYQILQGLAF 115
           L++VI E++ L+ VFE++  +L ++  D+   FPE V+ +  + +I+ G+ F
Sbjct: 148 LEDVIMEDERLFLVFEFLSMDL-KMYIDK---FPEGVVLDRRLVKIVTGINF 5
>26009
          Length = 886

 Score = 45.1 bits (105), Expect = 8e-05,   Method: Compositional matrix adjust.
 Identities = 17/50 (34%), Positives = 30/50 (60%)
 Frame = +3

Query: 93  RNKLFPESVIRNIMYQILQGLAFIHKHGFFHRDMKPENLLCMGPELVKIA 142
           RNK       +++M Q++  L F+H     HRD+KPEN+L + P+  +++
Sbjct: 690 RNKACGSREAKSVMKQLVSALDFMHSKQLVHRDIKPENVLILTPDFSRVS 839
>22005
          Length = 873

 Score = 45.1 bits (105), Expect = 8e-05,   Method: Compositional matrix adjust.
 Identities = 55/245 (22%), Positives = 94/245 (38%), Gaps = 59/245 (24%)
 Frame = +1

Query: 8   KQLGDGTYGSV----LMGKSNESGELVAIKR--MKRKFYSWDECMNL-----REVKSLKK 56
           + +G G +G V     +G ++  GEL+  KR  +  K    D   +L     RE   +  
Sbjct: 1   RDIGQGAFGRVSKLKFLGLASLVGELIPEKRP*LL*KMLKEDASEDLQSDFEREASLMAD 180

Query: 57  LNHANVIKLKEVIRENDHLYFVFEYMKE----NLYQLMKDRNKLFPESVIRNIMY----- 107
            +H N++KL  V      +  +FE+M +    +  +L    N   P S  +N++      
Sbjct: 181 FDHPNIVKLLGVCAIGKPMCLLFEFMSKGDLNDFLRLCSPENYNLPVSRSQNLVVDLEDG 360

Query: 108 -----------------------------------QILQGLAFIHKHGFFHRDMKPENLL 132
                                              QI  G+A++ +  + HRD+    + 
Sbjct: 361 LRVEVEAEECEKDTQSEDRDCSGMLXTKDQLYISQQISAGMAYLAQKDYVHRDLATRTVX 540

Query: 133 CMGPELVKIADFGLARELRSQPPY----TDYVSTRWYRAPEVLLRSSVYSSPIDVWAVGS 188
                   I+DFGLAR + S   Y     D +  RW     +L   S +S+  DVW+ G 
Sbjct: 541 -SRTT*S*ISDFGLARSVHSVDYYRGSEQDAIPIRWMPLEAILY--SKFSTQSDVWSFGV 711

Query: 189 IMAEL 193
           ++ E+
Sbjct: 712 VLWEI 726
>13078
          Length = 773

 Score = 44.3 bits (103), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 34/127 (26%), Positives = 59/127 (46%), Gaps = 18/127 (14%)
 Frame = -1

Query: 177 YSSPIDVWAVGSIMAELYTFRPLFPGTSEVDEIFKICQVLGT-----PKKS--------- 222
           +S P DVW++G IM ELYT   LF      + +  + ++LG+      KK+         
Sbjct: 746 WSQPCDVWSIGCIMFELYTGYTLFQTHDNKEHLAMMERILGSLPYRMAKKTKKQKYFYHG 567

Query: 223 --DWPEGYQLASSMNFRFPQCIPINLKTLIPNASS--EAIQLMTEMLNWDPKKRPTASQA 278
             DW E    +S+  +      P+      P+     +   LM +ML+++   R +  QA
Sbjct: 566 RLDWDEK---SSAGRYVRDNVKPLRRYVKDPDNEDHQQLFDLMDKMLSYEVSTRYSLRQA 396

Query: 279 LKHPYFQ 285
           ++HP+F+
Sbjct: 395 MRHPFFR 375
>05084
          Length = 1324

 Score = 43.9 bits (102), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 31/87 (35%), Positives = 44/87 (50%), Gaps = 2/87 (2%)
 Frame = +2

Query: 200 FPGTSEVDEIFKICQVLGTPKKSDWPEGYQLASSMNFRFPQCIPIN--LKTLIPNASSEA 257
            PG S VD++ +I +VLGTP +    E     S   F+FPQ I  +   K   P    EA
Sbjct: 2   LPGDSGVDQLVEIIKVLGTPTREQIREMNPNYS--EFKFPQ-IKAHPWTKVFRPRTPPEA 172

Query: 258 IQLMTEMLNWDPKKRPTASQALKHPYF 284
           IQL++ +L + P  R    +A  H +F
Sbjct: 173 IQLVSRLLEYTPSARIQPMEACAHAFF 253
>28157
          Length = 400

 Score = 43.9 bits (102), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 40/138 (28%), Positives = 68/138 (49%), Gaps = 14/138 (10%)
 Frame = +3

Query: 30  VAIKRM-----KRKFYSWDECMNLREVKSLKKLNHANVIKLKEVIRENDH-LYFVFEYMK 83
           VA+KR+     K+ F        ++E+K L +++H N++ L    R  DH +  V EY +
Sbjct: 9   VAVKRIESEQEKKSF--------MQELKQLSRVSHPNIVCLYGACR--DHPVCLVMEYAE 158

Query: 84  E-NLYQLMKDR--NKLFPESVIRNIMYQILQGLAFIHK---HGFFHRDMKPENLLCM--G 135
             +LY ++        +  +   N + Q   G+ ++H        HRD+KP NLL +  G
Sbjct: 159 GGSLYNVLHGSGPQPQYTAAHAMNWLLQCALGVEYLHGMKPKALIHRDLKPPNLLLIQCG 338

Query: 136 PELVKIADFGLARELRSQ 153
            +L KI DFG A ++ + 
Sbjct: 339 TKL-KICDFGTACDIHTH 389
>02638
          Length = 1490

 Score = 43.5 bits (101), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 38/125 (30%), Positives = 53/125 (42%)
 Frame = +1

Query: 160 VSTRWYRAPEVLLRSSVYSSPIDVWAVGSIMAELYTFRPLFPGTSEVDEIFKICQVLGTP 219
           + T  + APEVL R   Y    DVW+VG +M E+ T RP +      + +  I       
Sbjct: 19  LGTIAFMAPEVL-RGESYGRACDVWSVGCVMIEMCTCRPPWNSHDISNHLALI------- 174

Query: 220 KKSDWPEGYQLASSMNFRFPQCIPINLKTLIPNASSEAIQLMTEMLNWDPKKRPTASQAL 279
                   +++ASS++   P  IP N+       S     LM   L  D   RP+A   L
Sbjct: 175 --------FKIASSVD---PPPIPENM-------SPPVRDLMLRCLEQDSDFRPSAKDLL 300

Query: 280 KHPYF 284
            HP F
Sbjct: 301 MHPLF 315
>21433
          Length = 590

 Score = 43.5 bits (101), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 30/93 (32%), Positives = 44/93 (47%)
 Frame = +2

Query: 106 MYQILQGLAFIHKHGFFHRDMKPENLLCMGPELVKIADFGLARELRSQPPYTDYVSTRWY 165
           +YQ+   L + H     HRD+KPENLL      +KIADFG +    S    T    T  Y
Sbjct: 185 IYQLSSALEYCHYRKVIHRDIKPENLLLGLKGDLKIADFGWSVHAPSS-RRTTMCGTLDY 361

Query: 166 RAPEVLLRSSVYSSPIDVWAVGSIMAELYTFRP 198
             PE ++    +   +D+W++G +  E     P
Sbjct: 362 LPPE-MVEGKTHDENVDLWSLGVLCYEFLVGTP 457
>21800
          Length = 855

 Score = 43.1 bits (100), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 23/61 (37%), Positives = 37/61 (60%), Gaps = 2/61 (3%)
 Frame = +2

Query: 74  HLYFVFEYMKENLYQLMKDRN-KLFPESVIRNIMYQILQGLAFIH-KHGFFHRDMKPENL 131
           H+  VFE +  NL +L+   N +  P   ++ I+ Q+L+GL ++H K    H D+KPEN+
Sbjct: 551 HVCMVFEVLGYNLLKLIIRSNYQGIPVHNVKLIIRQVLEGLNYLHAKCNIIHTDIKPENI 730

Query: 132 L 132
           L
Sbjct: 731 L 733
>07291
          Length = 833

 Score = 42.7 bits (99), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 28/93 (30%), Positives = 47/93 (50%), Gaps = 5/93 (5%)
 Frame = +1

Query: 108 QILQGLAFIHKHGFFHRDMKPENLLCMGPELVKIADFGLARELRSQPPYTDYVS-----T 162
           QI  G+A++ +    HR++   N +      ++++D+G+   L  Q  YT   S      
Sbjct: 73  QIADGMAYLQEVKVVHRNLAARNCIVTEDGRLQLSDYGVTGSLFPQSYYTADDSPARDLV 252

Query: 163 RWYRAPEVLLRSSVYSSPIDVWAVGSIMAELYT 195
           +W  APE  + +  +SS  DVWA G ++ EL T
Sbjct: 253 KWM-APET-IDNFHFSSKSDVWAFGVVLWELLT 345
>18481
          Length = 437

 Score = 42.7 bits (99), Expect = 5e-04,   Method: Composition-based stats.
 Identities = 27/79 (34%), Positives = 40/79 (50%), Gaps = 4/79 (5%)
 Frame = -1

Query: 77  FVFEYMKENLYQLMKDRNKLFPESVIRNIMYQILQGLAFIHKHGFFHRDMKPENLLCMG- 135
            V E +  +L +L     + F    I  +  Q+L  L FIH+  F HRD+KP+N L MG 
Sbjct: 266 LVMELLGPSLEELFVICKRRFTLKTILMVSDQLLSRLEFIHQKCFIHRDLKPDNFL-MGL 90

Query: 136 ---PELVKIADFGLARELR 151
                 + I DFGL++  +
Sbjct: 89  GRHCHRLYIIDFGLSKRYK 33
>11185
          Length = 473

 Score = 42.4 bits (98), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 31/120 (25%), Positives = 51/120 (42%), Gaps = 26/120 (21%)
 Frame = +1

Query: 102 IRNIMYQILQGLAFIHKHGFFHRDMKPENLLCMGPELVKIADFGL--------------- 146
           IR+    ++ GL +IH  G    D++P  +L     ++K ADFGL               
Sbjct: 7   IRDFGIHLVTGLHYIHSLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKF 186

Query: 147 -----------ARELRSQPPYTDYVSTRWYRAPEVLLRSSVYSSPIDVWAVGSIMAELYT 195
                      A E+  Q P +   +   Y APEV  + +  S   D+WA+G +  E+++
Sbjct: 187 AEAGDQWNIQSAEEMMKQVPTSGSPT---YMAPEV-FQGAEPSIMSDLWALGCVFYEMFS 354
>16708
          Length = 1397

 Score = 41.6 bits (96), Expect = 9e-04,   Method: Compositional matrix adjust.
 Identities = 53/220 (24%), Positives = 91/220 (41%), Gaps = 28/220 (12%)
 Frame = -1

Query: 7    MKQLGDGTYGSVLMGKSNESGELVAIKRMKRKFYSWDECMNLREVKS---LKKLNHANVI 63
            ++ LG G +G V   +   + E  A+K      +S DE   L  ++    L ++  A V 
Sbjct: 1388 LQVLGKGVFGKVYEARLLSTHEKAALKTSILCHHSLDEVEALGRIEGGFYLAQMFGAWVT 1209

Query: 64   KLKEVIRENDHLYFVFEYMKENLYQLMKDRNKLFP-----ESVIRNIMYQILQGLAFIHK 118
             L    + N  L+F       N+Y   K  NK  P      +++  I  Q +  L  IH+
Sbjct: 1208 CLP-FPKMNILLHFYEMGPLCNVYAHYK--NKEMPIRWSNPAMVCCIAGQXVCALEHIHE 1038

Query: 119  HGFFHRDMKPENLLCMGPELVKIADFGLARELRSQPPYTDYVS-------TRWYRAPEVL 171
             G  H D+K +N+L       K+ D+G+A+  +  P  T+  S       T + R P  +
Sbjct: 1037 LGVVHMDVKADNVLVDAHGNCKLTDYGIAQLYKVYPAPTETHSSGCTNKRTFYTRPPATM 858

Query: 172  LRSSVYSSPID------------VWAV-GSIMAELYTFRP 198
              S  +S   D            +W + G+++  ++  RP
Sbjct: 857  TPSERFSEEGDGIGTDYFRLGQMLWTLTGAVLLHVWVSRP 738
>18996
          Length = 491

 Score = 41.2 bits (95), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 30/96 (31%), Positives = 47/96 (48%), Gaps = 7/96 (7%)
 Frame = +2

Query: 122 FHRDMKPENLLCMGPELVKIADFGLARELRSQPPYTDY----VSTRWYRAPEVLLRSSVY 177
            HRD+   N+L +    VKI+DFGLA+   +   Y       +  +WY +PE  + +  +
Sbjct: 2   IHRDLAARNIL-VDRSCVKISDFGLAQFANADGYYYGISQRDIPIKWY-SPEA-IETCKF 172

Query: 178 SSPIDVWAVGSIMAELYT---FRPLFPGTSEVDEIF 210
           SS  DVW+ G  + E+++      L PG     E F
Sbjct: 173 SSYSDVWSYGVTLFEMFSRGEIPNLLPGHDLTQEEF 280
>17253
          Length = 483

 Score = 40.8 bits (94), Expect = 0.002,   Method: Composition-based stats.
 Identities = 34/149 (22%), Positives = 64/149 (42%), Gaps = 13/149 (8%)
 Frame = -1

Query: 28  ELVAIKRMKRKFYSWDECMNLREVKSLKKL-NHANVIKLKEVIRENDHLYFVFEYM-KEN 85
           + VA+K         ++   LRE+  ++KL  H NV+        +D    + E+    +
Sbjct: 465 DTVAVKTHNEAATDAEKSEFLRELSIMRKLPRHPNVVSFMGCCTMSDPALILMEFCCHGD 286

Query: 86  LYQLMKDRN---KLFPESVIRNIM--------YQILQGLAFIHKHGFFHRDMKPENLLCM 134
           L   ++ R     +F  S   ++           + +G+A +  +   HRD+   N+L  
Sbjct: 285 LLSFLRKRRPDRTVFLTSTANDLTARDFFSFALHVARGMAHVANNKIVHRDVAARNVLIS 106

Query: 135 GPELVKIADFGLARELRSQPPYTDYVSTR 163
              + K++DFGL+R +  Q    + VS R
Sbjct: 105 ERNVCKVSDFGLSRRVGDQNDVYEIVSRR 19
>12786
          Length = 460

 Score = 39.3 bits (90), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 28/115 (24%), Positives = 48/115 (41%), Gaps = 22/115 (19%)
 Frame = -3

Query: 108 QILQGLAFIHKHGFFHRDMKPENLLCMGPELVKIADFGLARELRSQPPYT---DYVSTRW 164
           ++L+ +  +H  G  H D+KP N + +   L K+ DFG+A  L+           V T  
Sbjct: 386 EMLRAVKALHNEGVIHSDLKPANFMLVAGNL-KLIDFGIANTLQQDKTSVLKDSRVGTPS 210

Query: 165 YRAPEVLLRSSVYSSP-------------------IDVWAVGSIMAELYTFRPLF 200
           Y +PE ++ +   S+                     DVW++G I+  +   R  F
Sbjct: 209 YMSPEAIMAACDDSADDSMEEDGHRTKPKYKVGVRSDVWSLGCILYNMVYGRTPF 45
>31757
          Length = 540

 Score = 38.1 bits (87), Expect = 0.011,   Method: Compositional matrix adjust.
 Identities = 14/24 (58%), Positives = 22/24 (91%)
 Frame = -2

Query: 469 STASTAKQYYLKQSRYLPGVNPKN 492
           S+ ++AKQ+Y+ ++RYLPG+NPKN
Sbjct: 350 SSNNSAKQHYISKARYLPGINPKN 279
>37602
          Length = 804

 Score = 37.4 bits (85), Expect = 0.018,   Method: Compositional matrix adjust.
 Identities = 22/70 (31%), Positives = 33/70 (47%)
 Frame = -1

Query: 75  LYFVFEYMKENLYQLMKDRNKLFPESVIRNIMYQILQGLAFIHKHGFFHRDMKPENLLCM 134
           L+   EY      Q +        E  I  +  + L+GL ++H+ G  HRD+K  N+L  
Sbjct: 294 LWIAMEYCGGGSMQDIYHVTGPLTEPQIAFVCRETLKGLHYLHRRGKMHRDIKGANILLT 115

Query: 135 GPELVKIADF 144
               VK+ADF
Sbjct: 114 EEGDVKLADF 85
>07836
          Length = 1478

 Score = 36.6 bits (83), Expect = 0.028,   Method: Compositional matrix adjust.
 Identities = 48/192 (25%), Positives = 82/192 (42%), Gaps = 25/192 (13%)
 Frame = -1

Query: 27   GELVAIKRMKRKFYSWDECMNLREVKSLKK--LNHANVIKLKEVIREND----HLYFVFE 80
            GE VA+K     F++ +E    RE +  +   L H N++       +       L+ + +
Sbjct: 1478 GENVAVK----IFFTTEEASWFRETELYQTVLLRHENILGFIAADIKGTGSWTQLFLITD 1311

Query: 81   YMKE-NLYQLMKDRNKLFPESVIRNIMYQILQGLAFIH--------KHGFFHRDMKPENL 131
            Y +  +L+  +  R  +   S +  + +  + GLA +H        K    HRD+K +N+
Sbjct: 1310 YHENGSLHDYLLSR--VLDSSEMLALAHSAICGLAHLHIEIFGTRGKPAIAHRDIKSKNI 1137

Query: 132  LCMGPELVKIADFGLARELRSQPPYTDYV-----STRWYRAPEVL-----LRSSVYSSPI 181
            L        IAD GLA    S+    D        T+ Y APEVL     +++       
Sbjct: 1136 LVKKNGTCCIADLGLAVRYISESNEVDVAPNPRQGTKRYMAPEVLEMLLNVKNFDAFKQA 957

Query: 182  DVWAVGSIMAEL 193
            D++A G +M E+
Sbjct: 956  DMYAFGLVMWEI 921
>14104
          Length = 573

 Score = 36.2 bits (82), Expect = 0.039,   Method: Compositional matrix adjust.
 Identities = 29/103 (28%), Positives = 45/103 (43%), Gaps = 11/103 (10%)
 Frame = +1

Query: 252 NASSEAIQLMTEMLNWDPKKRPTASQALKHPYFQVGQVLGSSAHHLDTKQTLHK------ 305
           NA+ +A+  M   L  DP +R T  Q L+HPY  +   + +        +  +K      
Sbjct: 85  NAAPQAMSFMQSCLKMDPAERLTCHQLLQHPYMDLNMEMVTEGKRETVNRNKNKSRTMNY 264

Query: 306 -----QLQPLEPKPSSSERDPKPLPNILDQPAGQPQPKQGHQP 343
                Q  P+ P  S+S     P+PN   QPA + +P+  H P
Sbjct: 265 PMPFQQQLPMLPTNSTS-----PVPNPKYQPAPKQKPRFDHLP 378
>00638
          Length = 1595

 Score = 35.8 bits (81), Expect = 0.051,   Method: Compositional matrix adjust.
 Identities = 26/86 (30%), Positives = 44/86 (51%), Gaps = 7/86 (8%)
 Frame = +2

Query: 50  EVKSLKKLNH-ANVIKLKEVIRE--NDHLYFVFEYMK----ENLYQLMKDRNKLFPESVI 102
           E+K L+ L    NVI L  ++++  +     +FE++     + LYQ   D +       I
Sbjct: 266 EIKILENLRGGTNVITLLAIVKDPVSRTPALIFEHVNNTDFKQLYQTFTDYD-------I 424

Query: 103 RNIMYQILQGLAFIHKHGFFHRDMKP 128
           R  +Y++++ L F H  G  HRD+KP
Sbjct: 425 RFYLYELMKALDFCHSMGIMHRDVKP 502
>18929
          Length = 440

 Score = 33.9 bits (76), Expect = 0.18,   Method: Compositional matrix adjust.
 Identities = 16/40 (40%), Positives = 23/40 (57%)
 Frame = +1

Query: 249 LIPNASSEAIQLMTEMLNWDPKKRPTASQALKHPYFQVGQ 288
            I   S E  Q++  M++ DP++RPTA+Q L HP     Q
Sbjct: 34  FINTISVELQQVIRRMMSPDPRQRPTANQLLAHPTLAALQ 153
>20513
          Length = 405

 Score = 33.5 bits (75), Expect = 0.24,   Method: Composition-based stats.
 Identities = 12/36 (33%), Positives = 23/36 (63%)
 Frame = -1

Query: 251 PNASSEAIQLMTEMLNWDPKKRPTASQALKHPYFQV 286
           P  +      +  ML +DP++R TA+Q+L+HP+ ++
Sbjct: 306 PKDAKAFADFLAPMLEFDPEQRATAAQSLQHPWLKL 199
>16350
          Length = 1108

 Score = 32.3 bits (72), Expect = 0.64,   Method: Compositional matrix adjust.
 Identities = 12/36 (33%), Positives = 23/36 (63%)
 Frame = +3

Query: 251 PNASSEAIQLMTEMLNWDPKKRPTASQALKHPYFQV 286
           P  +      +  ML +DP++R TA+Q+L+HP+ ++
Sbjct: 738 PKDAKAFADFLAPMLEFDPEQRATAAQSLQHPWLKL 845
>35032
          Length = 465

 Score = 32.0 bits (71), Expect = 0.66,   Method: Composition-based stats.
 Identities = 14/41 (34%), Positives = 23/41 (56%)
 Frame = +3

Query: 244 INLKTLIPNASSEAIQLMTEMLNWDPKKRPTASQALKHPYF 284
           + +KT +  ++     L+  +LN+DP KR T   AL HP+ 
Sbjct: 102 VGVKTCVK*SAFLFFDLVKRLLNYDPSKRLTPXXALAHPFL 224
>13840
          Length = 446

 Score = 30.4 bits (67), Expect = 2.4,   Method: Composition-based stats.
 Identities = 23/126 (18%), Positives = 58/126 (46%), Gaps = 6/126 (4%)
 Frame = -1

Query: 7   MKQLGDGTYGSVLMGKSNESGELVAIKRMKRKFYSWDECMNLREVKSLKKLNHAN-VIKL 65
           M ++G G YG+V   +   +  ++A+KR++      ++   L ++  + + N+   +++ 
Sbjct: 380 MGEIGRGNYGTVNKMRHKITSTVMAVKRIRSTVEEREQKQLLMDLDVVMRSNNCPFIVQF 201

Query: 66  KEVIRENDHLYFVFEYMKENLYQLMK----DRNKLFPESVIRNIMYQILQGLAFIHKH-G 120
              + +    +   E M+ +L +  K    +     PE+++  I    L+ L ++ +   
Sbjct: 200 YGALFKEGDCWICMELMETSLDKFYKFVYGEMQSSIPENILGKITVATLKALNYLKEELR 21

Query: 121 FFHRDM 126
             HRD+
Sbjct: 20  IIHRDV 3
>15549
          Length = 470

 Score = 24.3 bits (51), Expect(2) = 3.1,   Method: Composition-based stats.
 Identities = 10/34 (29%), Positives = 19/34 (55%)
 Frame = -1

Query: 2   NRYTTMKQLGDGTYGSVLMGKSNESGELVAIKRM 35
           + +  ++Q+G G YG V   K+    +  A+KR+
Sbjct: 218 DEFECIEQMGKGGYGIVFRAKNKVDEQEYAVKRI 117

 Score = 24.3 bits (51), Expect(2) = 3.1,   Method: Composition-based stats.
 Identities = 8/17 (47%), Positives = 14/17 (82%)
 Frame = -3

Query: 48 LREVKSLKKLNHANVIK 64
          LREV++L KL+H  +++
Sbjct: 81 LREVQTLAKLDHVGIVR 31
>36002
          Length = 253

 Score = 29.6 bits (65), Expect = 3.4,   Method: Composition-based stats.
 Identities = 13/30 (43%), Positives = 20/30 (66%)
 Frame = +1

Query: 254 SSEAIQLMTEMLNWDPKKRPTASQALKHPY 283
           SS A  L+  +L  +P+KR +A+  LKHP+
Sbjct: 118 SSSAKDLIRHLLVREPRKRYSAADVLKHPW 207
>29722
          Length = 352

 Score = 29.3 bits (64), Expect = 5.0,   Method: Compositional matrix adjust.
 Identities = 11/27 (40%), Positives = 18/27 (66%)
 Frame = -3

Query: 259 QLMTEMLNWDPKKRPTASQALKHPYFQ 285
           +L+  ML  DP KRP+ ++ L+ PY +
Sbjct: 257 ELLRAMLYQDPAKRPSINRILRDPYIR 177
>31595
          Length = 300

 Score = 28.9 bits (63), Expect = 5.9,   Method: Composition-based stats.
 Identities = 12/36 (33%), Positives = 24/36 (66%)
 Frame = -1

Query: 64  KLKEVIRENDHLYFVFEYMKENLYQLMKDRNKLFPE 99
           K+K  +R+NDH++        + +Q+M++ +K+FPE
Sbjct: 201 KMKVKLRQNDHVFC-------DQFQVMRNHDKVFPE 115
>17516
          Length = 453

 Score = 28.9 bits (63), Expect = 6.0,   Method: Composition-based stats.
 Identities = 13/30 (43%), Positives = 19/30 (63%)
 Frame = -3

Query: 165 YRAPEVLLRSSVYSSPIDVWAVGSIMAELY 194
           Y APEVLL+   Y    DV+++  I+ EL+
Sbjct: 421 YMAPEVLLQKGQYDMKADVYSLAIILWELW 332
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|225543495|ref|NP_766265.3| YTH domain family 3
isoform 1 [Mus musculus]
         (596 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

37635                                                                 196   3e-50
26363                                                                  90   3e-18
11885                                                                  37   0.018
>37635
          Length = 2610

 Score =  196 bits (497), Expect = 3e-50,   Method: Compositional matrix adjust.
 Identities = 86/110 (78%), Positives = 99/110 (90%)
 Frame = +3

Query: 468 GKGPLYLLFSVNGSGHFCGVAEMKSVVDYNAYAGVWSQDKWKGKFEVKWIFVKDVPNNQL 527
           GKGP+YLL+SVNGSGHFCG+AEM S +DYN  A VW+QDKWKG+F VKW++VKDVPN+QL
Sbjct: 9   GKGPIYLLYSVNGSGHFCGIAEMLSPIDYNKNASVWAQDKWKGQFTVKWVYVKDVPNSQL 188

Query: 528 RHIRLENNDNKPVTNSRDTQEVPLEKAKQVLKIIATFKHTTSIFDDFAHY 577
           RHIRLENN+NKPVTNSRDTQEVP EK KQV+KI+  +KHTTSIFDDF HY
Sbjct: 189 RHIRLENNENKPVTNSRDTQEVPPEKGKQVMKILHNYKHTTSIFDDFTHY 338
>26363
          Length = 442

 Score = 89.7 bits (221), Expect = 3e-18,   Method: Composition-based stats.
 Identities = 50/108 (46%), Positives = 63/108 (58%)
 Frame = -2

Query: 470 GPLYLLFSVNGSGHFCGVAEMKSVVDYNAYAGVWSQDKWKGKFEVKWIFVKDVPNNQLRH 529
            P+YL FS  GS HF GVAEM S VDY+   G        G F+VKW +VKDVP+ +  H
Sbjct: 429 APVYLFFSCVGSRHFHGVAEMTSAVDYDDRFG---NGFLHGGFDVKWHYVKDVPSMRFSH 259

Query: 530 IRLENNDNKPVTNSRDTQEVPLEKAKQVLKIIATFKHTTSIFDDFAHY 577
           I++   DNKP+  SR+  E+ L +  Q LK+   F HTTSI  D   Y
Sbjct: 258 IKV-GEDNKPMFRSRNGDELTLSRGLQALKVFHDFNHTTSILMDTDFY 118
>11885
          Length = 479

 Score = 37.4 bits (85), Expect = 0.018,   Method: Compositional matrix adjust.
 Identities = 27/84 (32%), Positives = 41/84 (48%), Gaps = 6/84 (7%)
 Frame = +3

Query: 472 LYLLFSVNGSGHFCGVAEM--KSVVDYNAYAGVW----SQDKWKGKFEVKWIFVKDVPNN 525
           LY  FSV  SG F G A +  +S  D+     V     +       F++ WI  +++P +
Sbjct: 213 LYSSFSVKESGKFQGYARLAAESTKDHPPIRWVLPPGMNARVLSAVFKLDWIDRRELPFS 392

Query: 526 QLRHIRLENNDNKPVTNSRDTQEV 549
           +  H+    N+NKPV   RD QE+
Sbjct: 393 KTNHLHNPWNENKPVKIGRDGQEI 464
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|116517303|ref|NP_032982.2| polypyrimidine tract
binding protein 1 isoform 2 [Mus musculus]
         (529 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

06580                                                                 195   4e-50
02882                                                                 189   2e-48
23395                                                                 156   3e-38
25431                                                                  97   2e-20
30917                                                                  94   2e-19
21440                                                                  80   2e-15
28718                                                                  68   7e-12
27488                                                                  42   5e-04
03903                                                                  41   0.001
28652                                                                  35   0.057
03678                                                                  33   0.28 
21527                                                                  33   0.35 
09968                                                                  33   0.38 
08958                                                                  32   0.43 
15994                                                                  32   0.91 
36693                                                                  28   6.4  
09572                                                                  28   8.4  
05987                                                                  28   9.8  
>06580
          Length = 1597

 Score =  195 bits (496), Expect = 4e-50,   Method: Compositional matrix adjust.
 Identities = 92/134 (68%), Positives = 113/134 (84%)
 Frame = +1

Query: 396 KLHGKSVRITLSKHQSVQLPREGQEDQGLTKDYGSSPLHRFKKPGSKNFQNIFPPSATLH 455
           +L GK++R+  S+H  VQ+P+EGQ D GLTKD+ +SPLHRFK+PGSKN QNIFPPSA LH
Sbjct: 10  RLWGKNIRVAQSRHAIVQMPKEGQPDAGLTKDFVNSPLHRFKRPGSKNCQNIFPPSAVLH 189

Query: 456 LSNIPPSVSEDDLKSLFSSNGGVVKGFKFFQKDRKMALIQMGSVEEAVQALIELHNHDLG 515
           LSNIPPS++E+ L+S F ++ G V+GFKFFQKDRKMALIQ+ SV+EA+ ALI +HN  LG
Sbjct: 190 LSNIPPSITEEQLQSWF-TDYGTVRGFKFFQKDRKMALIQLNSVDEAILALIGMHNMQLG 366

Query: 516 ENHHLRVSFSKSTI 529
           EN HLRVSFSKSTI
Sbjct: 367 ENSHLRVSFSKSTI 408

 Score = 29.3 bits (64), Expect = 3.6,   Method: Compositional matrix adjust.
 Identities = 15/52 (28%), Positives = 27/52 (51%), Gaps = 1/52 (1%)
 Frame = +1

Query: 56  PSRVIHVRKLPSDVTEGEVISLGLPFGKVTNL-LMLKGKNQAFIEMNTEEAA 106
           PS V+H+  +P  +TE ++ S    +G V       K +  A I++N+ + A
Sbjct: 172 PSAVLHLSNIPPSITEEQLQSWFTDYGTVRGFKFFQKDRKMALIQLNSVDEA 327
>02882
          Length = 2876

 Score =  189 bits (481), Expect = 2e-48,   Method: Compositional matrix adjust.
 Identities = 89/134 (66%), Positives = 110/134 (82%)
 Frame = -1

Query: 396  KLHGKSVRITLSKHQSVQLPREGQEDQGLTKDYGSSPLHRFKKPGSKNFQNIFPPSATLH 455
            ++ GK VR+  S+H  VQ+P+EGQ D GLTKD+  SPLHRFK+PGSKN QNIFPPSA LH
Sbjct: 2867 RVWGKHVRVAQSRHTIVQMPKEGQSDAGLTKDFAGSPLHRFKRPGSKNCQNIFPPSAVLH 2688

Query: 456  LSNIPPSVSEDDLKSLFSSNGGVVKGFKFFQKDRKMALIQMGSVEEAVQALIELHNHDLG 515
            LSNIPPSV+E+ +++ F ++ G VKGFKFFQKDR+MALI+M + +EAV +LI +HN  LG
Sbjct: 2687 LSNIPPSVTEEQIQNWF-ADYGTVKGFKFFQKDRRMALIEMNNADEAVLSLIGMHNTQLG 2511

Query: 516  ENHHLRVSFSKSTI 529
            EN HLRVSFSKSTI
Sbjct: 2510 ENSHLRVSFSKSTI 2469

 Score = 32.3 bits (72), Expect = 0.53,   Method: Compositional matrix adjust.
 Identities = 18/62 (29%), Positives = 32/62 (51%), Gaps = 2/62 (3%)
 Frame = -1

Query: 56   PSRVIHVRKLPSDVTEGEVISLGLPFGKVTNL-LMLKGKNQAFIEM-NTEEAANTMVNYY 113
            PS V+H+  +P  VTE ++ +    +G V       K +  A IEM N +EA  +++  +
Sbjct: 2705 PSAVLHLSNIPPSVTEEQIQNWFADYGTVKGFKFFQKDRRMALIEMNNADEAVLSLIGMH 2526

Query: 114  TS 115
             +
Sbjct: 2525 NT 2520
>23395
          Length = 1060

 Score =  156 bits (394), Expect = 3e-38,   Method: Compositional matrix adjust.
 Identities = 77/119 (64%), Positives = 92/119 (77%)
 Frame = -1

Query: 411  SVQLPREGQEDQGLTKDYGSSPLHRFKKPGSKNFQNIFPPSATLHLSNIPPSVSEDDLKS 470
            S + PR         +   +SPLHRFK+PGSKN QNIFPPSA LHLSNIPPS++E+ L+S
Sbjct: 1006 SFRCPRRASLMLV*PRTLSTSPLHRFKRPGSKNCQNIFPPSAVLHLSNIPPSITEEQLQS 827

Query: 471  LFSSNGGVVKGFKFFQKDRKMALIQMGSVEEAVQALIELHNHDLGENHHLRVSFSKSTI 529
             F+ + G V+GFKFFQKDRKMALIQ+ SV+EA+ ALI +HN  LGEN HLRVSFSKSTI
Sbjct: 826  WFT-DYGTVRGFKFFQKDRKMALIQLNSVDEAILALIGMHNMQLGENSHLRVSFSKSTI 653

 Score = 43.9 bits (102), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 18/33 (54%), Positives = 25/33 (75%)
 Frame = -3

Query: 396  KLHGKSVRITLSKHQSVQLPREGQEDQGLTKDY 428
            ++ GK VR+  S+H  VQ+P+EGQ D GLTKD+
Sbjct: 1052 RVWGKHVRVAQSRHTIVQMPKEGQPDAGLTKDF 954

 Score = 29.3 bits (64), Expect = 4.2,   Method: Compositional matrix adjust.
 Identities = 15/52 (28%), Positives = 27/52 (51%), Gaps = 1/52 (1%)
 Frame = -1

Query: 56  PSRVIHVRKLPSDVTEGEVISLGLPFGKVTNL-LMLKGKNQAFIEMNTEEAA 106
           PS V+H+  +P  +TE ++ S    +G V       K +  A I++N+ + A
Sbjct: 889 PSAVLHLSNIPPSITEEQLQSWFTDYGTVRGFKFFQKDRKMALIQLNSVDEA 734
>25431
          Length = 1623

 Score = 97.1 bits (240), Expect = 2e-20,   Method: Compositional matrix adjust.
 Identities = 65/209 (31%), Positives = 110/209 (52%), Gaps = 10/209 (4%)
 Frame = +2

Query: 331 GAGNSVLLVSNLNPERVTPQSLFILFGVYGDVQRVKILFNKKENALVQMADGSQAQLAMS 390
           G    V++V  LN E++  + +F LF +YG+V RVK L +K+  A+VQ+ DG   + A+ 
Sbjct: 608 GGQGCVVMVYGLNMEKMNCEKVFNLFCLYGNVVRVKFLKSKEGAAMVQLGDGISVERAIQ 787

Query: 391 HLNGHKLHGKSVRITLSKH---QSVQLPREGQEDQGLTKDYGSSPLHRFKKPGSKNFQNI 447
           +L+     G  +R++ SK    Q V  P E  +     KD+  +  +RF  P + +   I
Sbjct: 788 NLHNSFFFGSELRLSHSKQAFLQDVANPHELPDGSPSFKDFMGNRNNRFTNPEAASKNRI 967

Query: 448 FPPSATLHLSNIPPSVSEDDLKSLFSSNGG--VVKGFKFFQKDRK--MALIQMGSVEEAV 503
             P+  LH  N PP ++EDDL+ +F S+ G  +V+  +F  K  +    L++  S  +A+
Sbjct: 968 QSPAKVLHFFNAPPGITEDDLREIFESSSGKSIVRTKQFPSKTERSSTGLVEFESKSDAI 1147

Query: 504 QALIELHNHDLGENHH---LRVSFSKSTI 529
           +ALI  ++H +         ++ FS S I
Sbjct: 1148EALILTNHHPIPSTKTPFIFKLCFSASPI 1234

 Score = 94.0 bits (232), Expect = 1e-19,   Method: Compositional matrix adjust.
 Identities = 44/98 (44%), Positives = 68/98 (69%)
 Frame = +2

Query: 182 VLRIIVENLFYPVTLDVLHQIFSKFGTVLKIITFTKNNQFQALLQYADPVSAQHAKLSLD 241
           VL   + N  YP+T+DV+H I S +G VL+I+ F KN   Q ++++ +  SA+ AK SL+
Sbjct: 53  VLLFTILNPQYPITVDVMHTICSPYGQVLRIVIFKKNG-VQTMVEFDNLESAKRAKQSLN 229

Query: 242 GQNIYNACCTLRIDFSKLTSLNVKYNNDKSRDYTRPDL 279
           G ++Y+ CCTL+I+++K T LNV  N+++S DYT P L
Sbjct: 230 GADVYSGCCTLKIEYAKPTRLNVVKNDNESWDYTNPGL 343

 Score = 29.6 bits (65), Expect = 2.8,   Method: Compositional matrix adjust.
 Identities = 20/83 (24%), Positives = 37/83 (44%), Gaps = 1/83 (1%)
 Frame = +2

Query: 333 GNSVLLVSNLNPER-VTPQSLFILFGVYGDVQRVKILFNKKENALVQMADGSQAQLAMSH 391
            N+VLL + LNP+  +T   +  +   YG V R+ I        +V+  +   A+ A   
Sbjct: 44  ANNVLLFTILNPQYPITVDVMHTICSPYGQVLRIVIFKKNGVQTMVEFDNLESAKRAKQS 223

Query: 392 LNGHKLHGKSVRITLSKHQSVQL 414
           LNG  ++     + +   +  +L
Sbjct: 224 LNGADVYSGCCTLKIEYAKPTRL 292
>30917
          Length = 1616

 Score = 94.0 bits (232), Expect = 2e-19,   Method: Compositional matrix adjust.
 Identities = 49/114 (42%), Positives = 71/114 (62%), Gaps = 5/114 (4%)
 Frame = +3

Query: 182 VLRIIVENLFYPVTLDVLHQIFSKFGTVLKIITFTKNNQFQALLQYADPVSAQHAKLSLD 241
           VL   + N  YP+T+DV+H I S +G V +I+ F KN   QA++++    SA+ AK SL+
Sbjct: 120 VLLFTILNPQYPITVDVMHTICSPYGQVQRIVIFKKNG-VQAMIEFDGLESAKRAKQSLN 296

Query: 242 GQNIYNACCTLRIDFSKLTSLNVKYNNDKSRDYTRPDL-----PSGDSQPSLDQ 290
           G ++Y+ CCTL+I+F+K T LNV  N+ +S DYT P L     P    QP L +
Sbjct: 297 GADVYSGCCTLKIEFAKPTRLNVVKNDGESWDYTNPSLGKDHHPQQRGQPLLQE 458

 Score = 91.3 bits (225), Expect = 8e-19,   Method: Compositional matrix adjust.
 Identities = 58/191 (30%), Positives = 99/191 (51%), Gaps = 7/191 (3%)
 Frame = +1

Query: 331 GAGNSVLLVSNLNPERVTPQSLFILFGVYGDVQRVKILFNKKENALVQMADGSQAQLAMS 390
           G    V++V  LN +++  + LF LF +YG+V R+K L  K+  A+VQ+ DG   + A+ 
Sbjct: 667 GGQGCVVMVYGLNMQKINCEKLFNLFCLYGNVVRIKFLKTKEGAAMVQLGDGISVERAIQ 846

Query: 391 HLNGHKLHGKSVRITLSKH---QSVQLPREGQEDQGLTKDYGSSPLHRFKKPGSKNFQNI 447
           +L+     G  ++++ SK    Q V  P E  +     KD+  +  +RF  P + +   I
Sbjct: 847 NLHNCYFFGGELQLSPSKQAFLQDVMNPHELPDGTMAFKDFMGNRNNRFTNPEAASKNRI 1026

Query: 448 FPPSATLHLSNIPPSVSEDDLKSLFSSNGG----VVKGFKFFQKDRKMALIQMGSVEEAV 503
             PS  LH  N PP++SED++  +F S  G     +K F    +     L++  S  +A+
Sbjct: 1027QSPSKILHFYNAPPTISEDEVTEIFDSCCGKRPIRIKQFPSKTERSSTGLVEFESKNDAI 1206

Query: 504 QALIELHNHDL 514
           +ALI  ++H +
Sbjct: 1207EALILTNHHPI 1239

 Score = 32.3 bits (72), Expect = 0.53,   Method: Compositional matrix adjust.
 Identities = 21/82 (25%), Positives = 37/82 (45%), Gaps = 1/82 (1%)
 Frame = +3

Query: 334 NSVLLVSNLNPER-VTPQSLFILFGVYGDVQRVKILFNKKENALVQMADGSQAQLAMSHL 392
           N VLL + LNP+  +T   +  +   YG VQR+ I       A+++      A+ A   L
Sbjct: 114 NHVLLFTILNPQYPITVDVMHTICSPYGQVQRIVIFKKNGVQAMIEFDGLESAKRAKQSL 293

Query: 393 NGHKLHGKSVRITLSKHQSVQL 414
           NG  ++     + +   +  +L
Sbjct: 294 NGADVYSGCCTLKIEFAKPTRL 359
>21440
          Length = 603

 Score = 80.1 bits (196), Expect = 2e-15,   Method: Compositional matrix adjust.
 Identities = 54/138 (39%), Positives = 70/138 (50%), Gaps = 3/138 (2%)
 Frame = -3

Query: 8   IAVGTKRGSDELFSTCVSNGPFIMXXXXXXXNGNDSKKFKGDNRSAGVPSRVIHVRKLPS 67
              GTKRGSDEL S  V+NG  +          ND+KK K D       +R  H    P 
Sbjct: 472 FGAGTKRGSDELMSR-VTNGTGMSQEM------NDAKKVKLDGGGEPTIARCSH----PQ 326

Query: 68  DVTEGE---VISLGLPFGKVTNLLMLKGKNQAFIEMNTEEAANTMVNYYTSVAPVLRGQP 124
               G+     + G  F +       + +NQAF+E N E AA  MV+YY++    +R + 
Sbjct: 325 SAA*GDGDRCGAAGHAFWQDDQRARPQTENQAFLEFNEESAAVNMVSYYSTTTAQVRLKT 146

Query: 125 IYIQFSNHKELKTDSSPN 142
            Y+QFSNHKELKTDSS N
Sbjct: 145 CYVQFSNHKELKTDSSHN 92
>28718
          Length = 444

 Score = 68.2 bits (165), Expect = 7e-12,   Method: Compositional matrix adjust.
 Identities = 31/39 (79%), Positives = 36/39 (92%)
 Frame = +2

Query: 254 IDFSKLTSLNVKYNNDKSRDYTRPDLPSGDSQPSLDQTM 292
           ID+SKLT+LNVKYNNDKSRD+TRPDLP+GD  P+LDQ M
Sbjct: 2   IDYSKLTNLNVKYNNDKSRDFTRPDLPTGD--PNLDQVM 112

 Score = 32.0 bits (71), Expect(2) = 8e-05,   Method: Compositional matrix adjust.
 Identities = 14/23 (60%), Positives = 19/23 (82%)
 Frame = +2

Query: 334 NSVLLVSNLNPERVTPQSLFILF 356
           +SV+LVSNL+ E+VTP +LF L 
Sbjct: 338 SSVILVSNLDEEKVTPDALFTLL 406

 Score = 32.0 bits (71), Expect(2) = 8e-05,   Method: Composition-based stats.
 Identities = 13/14 (92%), Positives = 13/14 (92%)
 Frame = +1

Query: 356 FGVYGDVQRVKILF 369
           FGVYGDV RVKILF
Sbjct: 403 FGVYGDVHRVKILF 444
>27488
          Length = 462

 Score = 42.4 bits (98), Expect = 5e-04,   Method: Composition-based stats.
 Identities = 25/79 (31%), Positives = 41/79 (51%), Gaps = 1/79 (1%)
 Frame = +2

Query: 332 AGNSVLLVSNLNPERVTPQSLFILFGVYGDVQRVKILFNKKENALVQMADGSQAQLAMSH 391
           A  +V++V  ++ +      LF L  +YG+V R+K L  K+  A+VQM D    +  + H
Sbjct: 206 APAAVMMVYGMDHDTSNTDKLFNLVCLYGNVARIKFLKTKEGTAMVQMGDSVAVERCVQH 385

Query: 392 LNGHKL-HGKSVRITLSKH 409
           LN   +  G  ++I  SK 
Sbjct: 386 LNNIPVGTGGKIQIAFSKQ 442
>03903
          Length = 983

 Score = 41.2 bits (95), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 31/96 (32%), Positives = 45/96 (46%), Gaps = 14/96 (14%)
 Frame = -1

Query: 50  NRSAGVPSRVIHVRKLPSDVTEGEVISLGLPFGKVTNL------------LMLKG--KNQ 95
           N   G PSR ++++ L   VTE +   L   FG+  N             LM +G  K Q
Sbjct: 482 NYKEGEPSRRLYIKNLSKQVTEED---LHWVFGRYVNWDKEEEKSIFDIRLMKEGRMKGQ 312

Query: 96  AFIEMNTEEAANTMVNYYTSVAPVLRGQPIYIQFSN 131
           AF+ + TEE A   V    + A V +G+PI + F+ 
Sbjct: 311 AFVTLGTEEQARKAVK--DTNAFVFKGKPIAVHFAR 210
>28652
          Length = 918

 Score = 35.4 bits (80), Expect = 0.057,   Method: Compositional matrix adjust.
 Identities = 24/62 (38%), Positives = 31/62 (50%)
 Frame = -2

Query: 336 VLLVSNLNPERVTPQSLFILFGVYGDVQRVKILFNKKENALVQMADGSQAQLAMSHLNGH 395
           VL V NL  + VT   L   FG YG V+RVK +   K+   V   D   A  A+  L+G 
Sbjct: 197 VLYVRNLTGD-VTEDDLKEKFGAYGKVERVKKI---KDYGFVHYEDREDALKALDDLHGE 30

Query: 396 KL 397
           K+
Sbjct: 29  KI 24
>03678
          Length = 847

 Score = 33.1 bits (74), Expect = 0.28,   Method: Compositional matrix adjust.
 Identities = 24/70 (34%), Positives = 31/70 (44%), Gaps = 3/70 (4%)
 Frame = -3

Query: 412 VQLPREGQEDQGL---TKDYGSSPLHRFKKPGSKNFQNIFPPSATLHLSNIPPSVSEDDL 468
           VQ+  E Q  Q L   T D+  S  H +K           PP  T+ + N PP +SE D 
Sbjct: 692 VQVSVERQVVQYLYLKTVDWRHSEPHDWK-----------PPERTVFVGNTPPWLSEXDF 546

Query: 469 KSLFSSNGGV 478
           + LF   G V
Sbjct: 545 EXLFKCCGEV 516
>21527
          Length = 416

 Score = 32.7 bits (73), Expect = 0.35,   Method: Compositional matrix adjust.
 Identities = 23/64 (35%), Positives = 35/64 (54%), Gaps = 1/64 (1%)
 Frame = -3

Query: 199 LHQIFSKFGTVLKIITF-TKNNQFQALLQYADPVSAQHAKLSLDGQNIYNACCTLRIDFS 257
           L+ IFS+FG +L I+   T   + QA + + +  SA +A  S+ G   Y+    +RI FS
Sbjct: 390 LYAIFSQFGQILDIVAMKTLKMRGQAFVIFKEINSAANALRSMQGFPFYDK--PMRIQFS 217

Query: 258 KLTS 261
           K  S
Sbjct: 216 KKDS 205
>09968
          Length = 2913

 Score = 32.7 bits (73), Expect = 0.38,   Method: Compositional matrix adjust.
 Identities = 20/66 (30%), Positives = 29/66 (43%), Gaps = 5/66 (7%)
 Frame = -1

Query: 454  LHLSNIPPSVSEDDLKSLFSSNGGVVKGFKFFQKDRK-----MALIQMGSVEEAVQALIE 508
            L +S +  S    DLKSLF  +G V+ G K     R         + M S +E  + +  
Sbjct: 1386 LWVSGLSSSTRATDLKSLFGKHGKVI-GAKVVTNTRSPGRLCFGFVTMASADETTKCIQH 1210

Query: 509  LHNHDL 514
            LH  +L
Sbjct: 1209 LHRTEL 1192

 Score = 30.0 bits (66), Expect = 2.1,   Method: Compositional matrix adjust.
 Identities = 23/74 (31%), Positives = 34/74 (45%), Gaps = 6/74 (8%)
 Frame = -1

Query: 337  LLVSNLNPE-RVTPQSLFILFGVYGDVQRVKILFNKKENA-----LVQMADGSQAQLAMS 390
            L VS L+   R T   L  LFG +G V   K++ N +         V MA   +    + 
Sbjct: 1386 LWVSGLSSSTRAT--DLKSLFGKHGKVIGAKVVTNTRSPGRLCFGFVTMASADETTKCIQ 1213

Query: 391  HLNGHKLHGKSVRI 404
            HL+  +LHGK + +
Sbjct: 1212 HLHRTELHGKMISV 1171
>08958
          Length = 680

 Score = 32.3 bits (72), Expect = 0.43,   Method: Compositional matrix adjust.
 Identities = 19/48 (39%), Positives = 23/48 (47%), Gaps = 7/48 (14%)
 Frame = +2

Query: 448 FPPSATLHLSNIPPSVSEDDLKSLFSSNGGVV-------KGFKFFQKD 488
           F     L + N+ P VSEDD K LFS  G V        +GF F + D
Sbjct: 56  FTGRCRLFVGNLTPDVSEDDFKKLFSPFGEVSEAYVNSGRGFGFIRLD 199
>15994
          Length = 891

 Score = 31.6 bits (70), Expect = 0.91,   Method: Compositional matrix adjust.
 Identities = 23/87 (26%), Positives = 42/87 (48%)
 Frame = +3

Query: 334 NSVLLVSNLNPERVTPQSLFILFGVYGDVQRVKILFNKKENALVQMADGSQAQLAMSHLN 393
           NS + V NLN   ++ + +  +FG YG V  + +    K  A VQ     +A+ A++  N
Sbjct: 300 NSRVFVGNLNTFTLSKEDVDRIFGAYGAVTGISM---HKGYAFVQYNHPGEARRAVAFEN 470

Query: 394 GHKLHGKSVRITLSKHQSVQLPREGQE 420
           G    G+ + + +     V  P++G +
Sbjct: 471 GSSYGGQILDLNI-----VSEPKKGGQ 536
>36693
          Length = 273

 Score = 28.5 bits (62), Expect = 6.4,   Method: Composition-based stats.
 Identities = 13/31 (41%), Positives = 18/31 (58%)
 Frame = +2

Query: 186 IVENLFYPVTLDVLHQIFSKFGTVLKIITFT 216
           +  N+F P +L   H IFS F ++  II FT
Sbjct: 65  LYHNIFSPFSLSQYHNIFSTFLSLTTIIYFT 157
>09572
          Length = 1081

 Score = 28.1 bits (61), Expect = 8.4,   Method: Compositional matrix adjust.
 Identities = 19/57 (33%), Positives = 29/57 (50%)
 Frame = +3

Query: 179 QSPVLRIIVENLFYPVTLDVLHQIFSKFGTVLKIITFTKNNQFQALLQYADPVSAQH 235
           Q+P+    V++   P+ L  +H IFSK   +L I +F      QAL    +P S Q+
Sbjct: 561 QNPIFLRCVKSFQNPIVLL*IH*IFSKSNILLCIKSFQNPRILQALEDLTNPKSLQN 731
>05987
          Length = 1726

 Score = 28.1 bits (61), Expect = 9.8,   Method: Compositional matrix adjust.
 Identities = 20/63 (31%), Positives = 29/63 (46%)
 Frame = -2

Query: 452  ATLHLSNIPPSVSEDDLKSLFSSNGGVVKGFKFFQKDRKMALIQMGSVEEAVQALIELHN 511
             TL + N+PP+VS  D+KSL      V        K R+   +    VE A +AL + + 
Sbjct: 1170 CTLFVKNLPPTVSVTDIKSLSKDIKEVRLRIAVRAKQRQKKKMGFAYVEFASEALADKNY 991

Query: 512  HDL 514
              L
Sbjct: 990  KQL 982
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|73532758|ref|NP_001026984.1| PI-3-kinase-related
kinase SMG-1 [Mus musculus]
         (3658 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

26068                                                                 198   4e-50
19343                                                                 177   5e-44
19437                                                                 108   3e-23
18312                                                                  66   2e-10
28814                                                                  64   1e-09
30166                                                                  50   1e-05
06655                                                                  42   0.005
34349                                                                  35   0.72 
>26068
          Length = 460

 Score =  198 bits (503), Expect = 4e-50,   Method: Composition-based stats.
 Identities = 93/153 (60%), Positives = 110/153 (71%), Gaps = 4/153 (2%)
 Frame = +2

Query: 2324 MVGYIIGLGDRHLDNVLIDMTTGEVVHIDYNVCFEKGKSLRVPEKVPFRMTQNIETALGV 2383
            M+GYIIGLGDRHLDNVL+D+ TGEVVHIDYNVCFEKGK+LRVPE+VPFRMTQNIETALGV
Sbjct: 2    MIGYIIGLGDRHLDNVLVDLATGEVVHIDYNVCFEKGKNLRVPERVPFRMTQNIETALGV 181

Query: 2384 TGVEGVFRLSCEQVLHIMRRGRXXXXXXXXAFVYDPLVDWTXXXXXXXXXX----XXXXX 2439
            TGVEG+FRLS E VL  MR+GR        AFVYDPLVDWT                   
Sbjct: 182  TGVEGIFRLSSEHVLKTMRKGRETLLTLLEAFVYDPLVDWTTGNEGGYTGAFYGGEMVSV 361

Query: 2440 XQQAESKQSKREMEREITRSLFSSRVAEIKVNW 2472
                ++ +SK++ME+EIT  +F+ R AE+  +W
Sbjct: 362  GGMGDTGKSKKQMEQEITLGMFAIRCAEMSFSW 460
>19343
          Length = 430

 Score =  177 bits (450), Expect = 5e-44,   Method: Compositional matrix adjust.
 Identities = 82/138 (59%), Positives = 104/138 (75%)
 Frame = +3

Query: 2186 FHARHYSVTPLGTRSGLIQWVDGATPLFGLYKRWQQREAALQAQKAQDSYQTPQNPSIVP 2245
            + ARHYSVTPLG RSGLIQWV+GATPLF LYK+WQQREA  Q  K   +  T   P+ VP
Sbjct: 15   YRARHYSVTPLGPRSGLIQWVEGATPLFSLYKKWQQREAYAQTLKPGVAASTTNTPATVP 194

Query: 2246 RPSELYYSKIGPALKTVGLSLDVSRRDWPLHVMKAVLEELMEATPPNLLAKELWSSCTTP 2305
            RPSE+YYSK+ PALK  G+    +R++WP+ V++ VLE+LM+ TP +LLAKELW +    
Sbjct: 195  RPSEVYYSKLTPALKDKGIETSENRKEWPMSVLRKVLEDLMDDTPDDLLAKELWCASGGA 374

Query: 2306 DEWWRVTQSYARSTAVMS 2323
             EWW++ Q+Y+RSTAVMS
Sbjct: 375  GEWWQMVQTYSRSTAVMS 428
>19437
          Length = 700

 Score =  108 bits (271), Expect = 3e-23,   Method: Compositional matrix adjust.
 Identities = 75/203 (36%), Positives = 102/203 (50%)
 Frame = -1

Query: 3448 SVRQFLAEYKSWQDNIQTVLFTLVQAMGQVRSQEHVEMLQEITPTLKELKTQSQSIYNNL 3507
            S+R +L+ YK++ +NI + L T+V       S      +      L++L     SIY  L
Sbjct: 547  SIRHYLSSYKTFSENITSALKTVVSEDATRTS------MVATRAVLQDLVLLIPSIYERL 386

Query: 3508 VSFASPLVTDAANECSSPTSSATYQPSFAAAVRSNTGQKTQPDVMSQNAKKLIQKNLATS 3567
            + FA  L+    +   SP    T               K   D     A +L+     +S
Sbjct: 385  MQFAPSLLQQDQDVEDSPRQEVTRV------------MKRGEDPSGSPAHRLLMLKEGSS 242

Query: 3568 ADTPPSTIPGTGKSIACSPKKAVRDPKTGKAVQERNSYAVSVWKRVKAKLEGRDVDPNRR 3627
            +       P      A    K  RDP+TGKA+QERNSYAV VW+RVK KL+GRD D ++R
Sbjct: 241  SLLGS---PQHRDKSATKKDKVSRDPRTGKAIQERNSYAVGVWRRVKMKLDGRDPDSSKR 71

Query: 3628 MSVAEQVDYVIKEATNLDNLAQL 3650
            +SV EQVDYVIKEA +LDNL+ L
Sbjct: 70   LSVPEQVDYVIKEARDLDNLSVL 2
>18312
          Length = 560

 Score = 66.2 bits (160), Expect = 2e-10,   Method: Composition-based stats.
 Identities = 27/56 (48%), Positives = 37/56 (66%)
 Frame = -3

Query: 2305 PDEWWRVTQSYARSTAVMSMVGYIIGLGDRHLDNVLIDMTTGEVVHIDYNVCFEKG 2360
            P  W++   +Y RS A  S+VGYI+GLGDRH+ N+LID  T E++HID  +   K 
Sbjct: 180  PAHWFQCRLAYTRSVATNSIVGYILGLGDRHVMNILIDCVTAELIHIDLGIALNKA 13

 Score = 46.2 bits (108), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 26/78 (33%), Positives = 37/78 (47%)
 Frame = -2

Query: 2157 DLHLDERIMQFLSIVNTMFATINRQETPRFHARHYSVTPLGTRSGLIQWVDGATPLFGLY 2216
            DL  D  + Q   +VN + +      T + H R Y V PL   SGL+QW +G  PL G+ 
Sbjct: 559  DLRQDAIMQQVFGLVNRLLSHDPATSTRQLHIRTYKVVPLSRCSGLLQWCEGTRPLGGIS 380

Query: 2217 KRWQQREAALQAQKAQDS 2234
              W  R   L + ++  S
Sbjct: 379  D-WSARAQELWSTQSLSS 329
>28814
          Length = 372

 Score = 63.9 bits (154), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 35/87 (40%), Positives = 48/87 (55%), Gaps = 2/87 (2%)
 Frame = -3

Query: 2142 GSDGKSYPYLFKGLEDLHLDERIMQFLSIVNTMFATINRQETPR--FHARHYSVTPLGTR 2199
            GSDGK Y +L KG EDL  DER+MQ   +VN++    N  +T R       ++  PL T 
Sbjct: 331  GSDGKEYQFLLKGHEDLRQDERVMQLFGLVNSLLR--NNADTFRRNLTITRFAAIPLSTN 158

Query: 2200 SGLIQWVDGATPLFGLYKRWQQREAAL 2226
            SGLI WV     L  L + +++R+  L
Sbjct: 157  SGLIGWVPHCDTLHTLIRDYRERKKIL 77
>30166
          Length = 350

 Score = 50.4 bits (119), Expect = 1e-05,   Method: Composition-based stats.
 Identities = 22/55 (40%), Positives = 34/55 (61%), Gaps = 4/55 (7%)
 Frame = +3

Query: 1706 WRQLISSCPWLSEL----DENATEGVIKVWRKVVDRIFSLYKLSCSAYFTFLKLN 1756
            WR+   SC W +           + +++VW+ VV R++ LY+LS +AYFTFL+LN
Sbjct: 180  WRRRGGSCCWAARCCRWRGRQCVDQLLEVWKGVVKRVYHLYQLSATAYFTFLQLN 344
>06655
          Length = 1350

 Score = 41.6 bits (96), Expect = 0.005,   Method: Composition-based stats.
 Identities = 24/85 (28%), Positives = 44/85 (51%), Gaps = 2/85 (2%)
 Frame = -2

Query: 2303 TTPDEWWRVTQSYARSTAVMSMVGYIIGLGDRHLDNVLIDMTTGEVVHIDYNVCFEK--G 2360
            +  +E+    +++ +S A   +V Y++ + DRH  N+L+D   G ++HID+        G
Sbjct: 1295 SNSEEFLTAQKNFVQSCAGYCLVCYLMQVKDRHNGNILLD-AEGHIIHIDFGFILSTSPG 1119

Query: 2361 KSLRVPEKVPFRMTQNIETALGVTG 2385
            K+L   E  PF++T      +G  G
Sbjct: 1118 KNLGF-ENSPFKLTTEFVEVMGGQG 1047
>34349
          Length = 413

 Score = 34.7 bits (78), Expect = 0.72,   Method: Composition-based stats.
 Identities = 14/24 (58%), Positives = 20/24 (83%)
 Frame = +2

Query: 2330 GLGDRHLDNVLIDMTTGEVVHIDY 2353
            G+GDRHLDN+L+  T G++ HID+
Sbjct: 2    GVGDRHLDNLLL-TTNGKLFHIDF 70
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6754018|ref|NP_034443.1| guanine nucleotide-binding
protein, beta-5 subunit isoform 1 [Mus musculus]
         (395 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

14555                                                                 123   5e-50
17266                                                                 181   4e-46
30295                                                                 174   6e-44
30256                                                                  82   3e-16
13335                                                                  77   1e-14
17598                                                                  76   2e-14
02147                                                                  73   2e-13
27465                                                                  72   5e-13
00561                                                                  71   6e-13
12806                                                                  67   1e-11
02090                                                                  65   6e-11
19949                                                                  63   3e-10
12960                                                                  61   7e-10
03156                                                                  61   7e-10
01327                                                                  61   9e-10
26107                                                                  59   3e-09
17602                                                                  59   5e-09
02960                                                                  57   2e-08
10162                                                                  53   2e-07
12574                                                                  49   3e-06
18981                                                                  49   5e-06
01768                                                                  46   2e-05
03395                                                                  46   2e-05
11493                                                                  46   3e-05
34511                                                                  45   4e-05
01462                                                                  45   6e-05
15780                                                                  44   8e-05
13278                                                                  44   8e-05
37180                                                                  43   2e-04
21105                                                                  43   2e-04
01249                                                                  43   3e-04
19498                                                                  42   3e-04
35607                                                                  42   4e-04
31384                                                                  42   5e-04
14500                                                                  41   7e-04
19140                                                                  41   7e-04
04358                                                                  41   8e-04
26939                                                                  40   0.001
04088                                                                  40   0.002
29912                                                                  39   0.004
15118                                                                  39   0.005
19863                                                                  38   0.006
27270                                                                  37   0.018
07665                                                                  35   0.044
12140                                                                  35   0.050
27681                                                                  35   0.074
33180                                                                  34   0.085
31864                                                                  34   0.10 
17298                                                                  33   0.15 
01805                                                                  33   0.16 
15337                                                                  33   0.18 
01598                                                                  32   0.37 
10264                                                                  32   0.40 
27806                                                                  32   0.42 
21921                                                                  32   0.45 
03734                                                                  32   0.64 
03044                                                                  30   1.3  
00825                                                                  30   1.5  
28289                                                                  30   1.8  
30679                                                                  30   2.1  
31474                                                                  30   2.2  
07781                                                                  29   2.8  
08679                                                                  29   3.5  
07151                                                                  29   4.2  
15972                                                                  28   5.4  
30297                                                                  28   6.2  
19473                                                                  28   7.9  
25930                                                                  28   8.0  
16199                                                                  28   8.5  
12076                                                                  28   8.8  
>14555
          Length = 627

 Score =  123 bits (309), Expect(2) = 5e-50,   Method: Compositional matrix adjust.
 Identities = 56/73 (76%), Positives = 65/73 (89%)
 Frame = -2

Query: 272 QCVQAFETHESDVNSVRYYPSGDAFASGSDDATCRLYDLRADREVAIYSKESIIFGASSV 331
           +CVQ FE HE+D+N VR+YPSGDAFA+GSDDATCRL+DLRADREV  Y KESIIFG ++V
Sbjct: 626 ECVQMFEGHEADINCVRFYPSGDAFATGSDDATCRLFDLRADREVNCYRKESIIFGCNAV 447

Query: 332 DFSLSGRLLFAGY 344
           DFS+SGRLLF GY
Sbjct: 446 DFSVSGRLLFGGY 408

 Score = 92.8 bits (229), Expect(2) = 5e-50,   Method: Compositional matrix adjust.
 Identities = 37/51 (72%), Positives = 46/51 (90%)
 Frame = -3

Query: 345 NDYTINVWDVLKGSRVSILFGHENRVSTLRVSPDGTAFCSGSWDHTLRVWA 395
           NDYT+NVWD LKG R +IL+GH+NRVS LR+SPDGT+ C+GSWD+TLR+WA
Sbjct: 406 NDYTVNVWDALKGMRSTILYGHDNRVSCLRISPDGTSLCTGSWDYTLRIWA 254

 Score = 32.3 bits (72), Expect = 0.30,   Method: Compositional matrix adjust.
 Identities = 14/35 (40%), Positives = 21/35 (60%)
 Frame = -2

Query: 360 VSILFGHENRVSTLRVSPDGTAFCSGSWDHTLRVW 394
           V +  GHE  ++ +R  P G AF +GS D T R++
Sbjct: 620 VQMFEGHEADINCVRFYPSGDAFATGSDDATCRLF 516

 Score = 30.8 bits (68), Expect = 1.0,   Method: Compositional matrix adjust.
 Identities = 15/49 (30%), Positives = 23/49 (46%)
 Frame = -3

Query: 260 DKKAMVWDMRSGQCVQAFETHESDVNSVRYYPSGDAFASGSDDATCRLY 308
           D    VWD   G        H++ V+ +R  P G +  +GS D T R++
Sbjct: 403 DYTVNVWDALKGMRSTILYGHDNRVSCLRISPDGTSLCTGSWDYTLRIW 257

 Score = 29.6 bits (65), Expect = 2.3,   Method: Compositional matrix adjust.
 Identities = 16/56 (28%), Positives = 24/56 (42%)
 Frame = -3

Query: 211 LTASGDGTCALWDVESGQLLQSFHGHGADVLCLDLAPSETGNTFVSGGCDKKAMVW 266
           L  + D T  +WD   G      +GH   V CL ++P   G +  +G  D    +W
Sbjct: 418 LGVTNDYTVNVWDALKGMRSTILYGHDNRVSCLRISPD--GTSLCTGSWDYTLRIW 257
>17266
          Length = 480

 Score =  181 bits (460), Expect = 4e-46,   Method: Compositional matrix adjust.
 Identities = 85/149 (57%), Positives = 109/149 (73%)
 Frame = -1

Query: 243 LDLAPSETGNTFVSGGCDKKAMVWDMRSGQCVQAFETHESDVNSVRYYPSGDAFASGSDD 302
           L LAP     TFVSG CD  A +WD+R G C Q F  HESD+N++ Y+P+G AFA+GSDD
Sbjct: 441 LSLAPDM--RTFVSGACDASAKLWDVRDGMCKQTFSGHESDINAITYFPNGHAFATGSDD 268

Query: 303 ATCRLYDLRADREVAIYSKESIIFGASSVDFSLSGRLLFAGYNDYTINVWDVLKGSRVSI 362
           ATCRL+D+RAD+E+ +YS ++II G +SV FS SGRLL  GY+D+  N+WDVLK  R  +
Sbjct: 267 ATCRLFDIRADQEIGMYSHDNIICGITSVAFSKSGRLLLGGYDDFNCNIWDVLKQERTGV 88

Query: 363 LFGHENRVSTLRVSPDGTAFCSGSWDHTL 391
           L GH+NRVS L V+ DG+A  +GSWD  L
Sbjct: 87  LAGHDNRVSCLGVTEDGSAVATGSWDSFL 1

 Score = 43.1 bits (100), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 35/145 (24%), Positives = 60/145 (41%)
 Frame = -1

Query: 116 DKRRIVSSSQDGKVIVWDSFTTNKEHAVTMPCTWVMACAYAPSGCAIACGGLDNKCSVYP 175
           D R  VS + D    +WD      +   +   + + A  Y P+G A A G  D  C ++ 
Sbjct: 426 DMRTFVSGACDASAKLWDVRDGMCKQTFSGHESDINAITYFPNGHAFATGSDDATCRLFD 247

Query: 176 LTFDKNENMAAKKKSVAMHTNYLSACSFTNSDMQILTASGDGTCALWDVESGQLLQSFHG 235
           +  D+   M +    +      +++ +F+ S   +L    D  C +WDV   +      G
Sbjct: 246 IRADQEIGMYSHDNIICG----ITSVAFSKSGRLLLGGYDDFNCNIWDVLKQERTGVLAG 79

Query: 236 HGADVLCLDLAPSETGNTFVSGGCD 260
           H   V CL +  +E G+   +G  D
Sbjct: 78  HDNRVSCLGV--TEDGSAVATGSWD 10

 Score = 37.0 bits (84), Expect = 0.013,   Method: Compositional matrix adjust.
 Identities = 19/57 (33%), Positives = 30/57 (52%)
 Frame = -1

Query: 338 RLLFAGYNDYTINVWDVLKGSRVSILFGHENRVSTLRVSPDGTAFCSGSWDHTLRVW 394
           R   +G  D +  +WDV  G       GHE+ ++ +   P+G AF +GS D T R++
Sbjct: 420 RTFVSGACDASAKLWDVRDGMCKQTFSGHESDINAITYFPNGHAFATGSDDATCRLF 250
>30295
          Length = 593

 Score =  174 bits (441), Expect = 6e-44,   Method: Compositional matrix adjust.
 Identities = 89/191 (46%), Positives = 116/191 (60%), Gaps = 2/191 (1%)
 Frame = +2

Query: 35  YCSTCAEIMA--TDGLHENETLASLKSEAESLKGKLEEERAKLHDVELHQVAERVEALGQ 92
           +CST        T+GL     L +L+ E E LK ++ E R    D  L Q     +++G+
Sbjct: 29  HCSTLTHTFR*NTNGLTMTSELDALRQETEQLKNQIREARKAAGDTTLAQATASYDSVGR 208

Query: 93  FVMKTRRTLKGHGNKVLCMDWCKDKRRIVSSSQDGKVIVWDSFTTNKEHAVTMPCTWVMA 152
             M+TRRTL+ H  K+  M W  D R +VS+SQDGK+IVWD +TTNK HA+ +  +WVM 
Sbjct: 209 IQMRTRRTLRXHLAKIYAMHWATDSRNLVSASQDGKLIVWDGYTTNKVHAIPLRSSWVMT 388

Query: 153 CAYAPSGCAIACGGLDNKCSVYPLTFDKNENMAAKKKSVAMHTNYLSACSFTNSDMQILT 212
           CAYAPSG  +ACGGLDN CS+Y L     E      + +  HT YLS C F + D QI+T
Sbjct: 389 CAYAPSGGYVACGGLDNICSIYSL--KTREGNVRVSRELPGHTGYLSCCRFID-DNQIVT 559

Query: 213 ASGDGTCALWD 223
           +SGD TCALWD
Sbjct: 560 SSGDMTCALWD 592

 Score = 36.6 bits (83), Expect = 0.019,   Method: Compositional matrix adjust.
 Identities = 26/92 (28%), Positives = 36/92 (39%)
 Frame = +2

Query: 231 QSFHGHGADVLCLDLAPSETGNTFVSGGCDKKAMVWDMRSGQCVQAFETHESDVNSVRYY 290
           ++   H A +  +  A        VS   D K +VWD  +   V A     S V +  Y 
Sbjct: 227 RTLRXHLAKIYAMHWATDS--RNLVSASQDGKLIVWDGYTTNKVHAIPLRSSWVMTCAYA 400

Query: 291 PSGDAFASGSDDATCRLYDLRADREVAIYSKE 322
           PSG   A G  D  C +Y L+        S+E
Sbjct: 401 PSGGYVACGGLDNICSIYSLKTREGNVRVSRE 496

 Score = 29.6 bits (65), Expect = 2.2,   Method: Compositional matrix adjust.
 Identities = 28/134 (20%), Positives = 50/134 (37%), Gaps = 12/134 (8%)
 Frame = +2

Query: 188 KKSVAMHTNYLSACSFTNSDMQILTASGDGTCALWDVESGQLLQSFHGHGADVLCLDLAP 247
           ++++  H   + A  +      +++AS DG   +WD  +   + +     + V+    AP
Sbjct: 224 RRTLRXHLAKIYAMHWATDSRNLVSASQDGKLIVWDGYTTNKVHAIPLRSSWVMTCAYAP 403

Query: 248 SETGNTFVSGGCDKKAMVWDMRSGQCVQAFETHESDVNSVRYYPSGDAFAS--------- 298
           S  G     GG D    ++ ++         T E +V   R  P    + S         
Sbjct: 404 S--GGYVACGGLDNICSIYSLK---------TREGNVRVSRELPGHTGYLSCCRFIDDNQ 550

Query: 299 ---GSDDATCRLYD 309
               S D TC L+D
Sbjct: 551 IVTSSGDMTCALWD 592
>30256
          Length = 961

 Score = 82.4 bits (202), Expect = 3e-16,   Method: Compositional matrix adjust.
 Identities = 60/206 (29%), Positives = 99/206 (48%)
 Frame = +3

Query: 189 KSVAMHTNYLSACSFTNSDMQILTASGDGTCALWDVESGQLLQSFHGHGADVLCLDLAPS 248
           K++  HT  + +   T +   +++ S D +  +W+ ++G    + +GH + V CL L+  
Sbjct: 24  KNLIGHTGGVWSSQMTGN--TVISGSTDRSLKVWNADTGVCTHTLYGHSSTVRCLSLS-- 191

Query: 249 ETGNTFVSGGCDKKAMVWDMRSGQCVQAFETHESDVNSVRYYPSGDAFASGSDDATCRLY 308
             G   VSG  D    VWD+ SG C+     H + V  V+Y   G    SG+ D T R++
Sbjct: 192 --GKKVVSGSRDATLRVWDIESGHCLNVLLGHMAAVRCVQY--DGKRVVSGAXDYTVRVW 359

Query: 309 DLRADREVAIYSKESIIFGASSVDFSLSGRLLFAGYNDYTINVWDVLKGSRVSILFGHEN 368
           D   D    +++ +       S+ F   G  + +G  D +I VWDV  G  V  L GH++
Sbjct: 360 D--PDTASCLHTLQGHTNRVYSLQF--DGVYVVSGSLDTSIRVWDVRCGKLVHTLMGHQS 527

Query: 369 RVSTLRVSPDGTAFCSGSWDHTLRVW 394
             S L +  +     SG+ D T++VW
Sbjct: 528 LTSGLELKDN--LLVSGNADSTVKVW 599

 Score = 81.3 bits (199), Expect = 6e-16,   Method: Compositional matrix adjust.
 Identities = 59/193 (30%), Positives = 91/193 (47%), Gaps = 4/193 (2%)
 Frame = +3

Query: 206 SDMQILTASGDGTCALWDVESGQLLQSFHGHGADVLCLDLAPSETGNTFVSGGCDKKAMV 265
           S  ++++ S D T  +WD+ESG  L    GH A V C+       G   VSG  D    V
Sbjct: 189 SGKKVVSGSRDATLRVWDIESGHCLNVLLGHMAAVRCVQY----DGKRVVSGAXDYTVRV 356

Query: 266 WDMRSGQCVQAFETHESDVNSVRYYPSGDAFASGSDDATCRLYDLRADREV-AIYSKESI 324
           WD  +  C+   + H + V S+++   G    SGS D + R++D+R  + V  +   +S+
Sbjct: 357 WDPDTASCLHTLQGHTNRVYSLQF--DGVYVVSGSLDTSIRVWDVRCGKLVHTLMGHQSL 530

Query: 325 IFGASSVDFSLSGRLLFAGYNDYTINVWDVLKGSRVSILFG---HENRVSTLRVSPDGTA 381
             G       L   LL +G  D T+ VWDV  G  +  L G   H + V+ L+ +     
Sbjct: 531 TSG-----LELKDNLLVSGNADSTVKVWDVHTGKCLQTLLGPNKHRSAVTCLQFNKKFVV 695

Query: 382 FCSGSWDHTLRVW 394
            CS   D T+++W
Sbjct: 696 TCSD--DGTVKLW 728

 Score = 79.7 bits (195), Expect = 2e-15,   Method: Compositional matrix adjust.
 Identities = 54/169 (31%), Positives = 80/169 (47%)
 Frame = +3

Query: 226 SGQLLQSFHGHGADVLCLDLAPSETGNTFVSGGCDKKAMVWDMRSGQCVQAFETHESDVN 285
           +G+ +++  GH   V     +   TGNT +SG  D+   VW+  +G C      H S V 
Sbjct: 9   TGRCIKNLIGHTGGVW----SSQMTGNTVISGSTDRSLKVWNADTGVCTHTLYGHSSTVR 176

Query: 286 SVRYYPSGDAFASGSDDATCRLYDLRADREVAIYSKESIIFGASSVDFSLSGRLLFAGYN 345
            +    SG    SGS DAT R++D+ +   + +             D    G+ + +G  
Sbjct: 177 CLSL--SGKKVVSGSRDATLRVWDIESGHCLNVLLGHMAAVRCVQYD----GKRVVSGAX 338

Query: 346 DYTINVWDVLKGSRVSILFGHENRVSTLRVSPDGTAFCSGSWDHTLRVW 394
           DYT+ VWD    S +  L GH NRV +L+   DG    SGS D ++RVW
Sbjct: 339 DYTVRVWDPDTASCLHTLQGHTNRVYSLQF--DGVYVVSGSLDTSIRVW 479

 Score = 31.6 bits (70), Expect = 0.66,   Method: Compositional matrix adjust.
 Identities = 32/135 (23%), Positives = 56/135 (41%), Gaps = 1/135 (0%)
 Frame = +3

Query: 100 TLKGHGNKVLCMDWCKDKRRIVSSSQDGKVIVWDSFTTNKEHAVTMPCTWVMACAYAPSG 159
           TL+GH N+V  + +  D   +VS S D  + VWD       H  T+     +        
Sbjct: 387 TLQGHTNRVYSLQF--DGVYVVSGSLDTSIRVWDVRCGKLVH--TLMGHQSLTSGLELKD 554

Query: 160 CAIACGGLDNKCSVYPLTFDK-NENMAAKKKSVAMHTNYLSACSFTNSDMQILTASGDGT 218
             +  G  D+   V+ +   K  + +    K    H + ++   F      ++T S DGT
Sbjct: 555 NLLVSGNADSTVKVWDVHTGKCLQTLLGPNK----HRSAVTCLQFNKK--FVVTCSDDGT 716

Query: 219 CALWDVESGQLLQSF 233
             LWD+ +G  +++ 
Sbjct: 717 VKLWDLNTGDFIRNL 761
>13335
          Length = 863

 Score = 77.0 bits (188), Expect = 1e-14,   Method: Compositional matrix adjust.
 Identities = 68/238 (28%), Positives = 108/238 (45%), Gaps = 23/238 (9%)
 Frame = +1

Query: 180 KNENMAAKKKSVAMHTNYLSACSFTNSDMQILTASGDGTCALWDVESGQLLQSFHGHGAD 239
           K E   A K S+ +       C F+ S   +++ S D T  +W+V + +L++S+ GH   
Sbjct: 37  KGEYQHASKSSIRV-------CKFSPSSSHLVSGSDDDTICMWEVATQKLVRSYVGHEDS 195

Query: 240 VLCLDLAPSETGNTFVSGGCDKKAMVWDMRSGQCVQA---FETHESDVNSVRYYPS-GDA 295
           V+ L  +P+  G+  VSG  +    VWD   G C       + H+  V    + P+ G A
Sbjct: 196 VMALAYSPN--GHYLVSGSPNGDLYVWDASFGHCRHLTLRVDAHDLGVTCCEFSPTFGTA 369

Query: 296 -----------FASGSDDATCRLYDLRAD---REVAIYSKESIIFGASSV----DFSLSG 337
                       A+G  D   +L+   A     EV +  ++ I+ G S +     FS S 
Sbjct: 370 CAENSSTCNLLLATGGKDNLIKLWTFSAQVGSPEVTLQCRD-ILSGHSDLVMACAFSPSS 546

Query: 338 RLLFAGYNDYTINVWDVLKG-SRVSILFGHENRVSTLRVSPDGTAFCSGSWDHTLRVW 394
            LL +G  D ++ +WD +KG +  SI   H   V+    S DGT   SGS D  +++W
Sbjct: 547 ALLASGSFDKSVRLWDSVKGVALFSIEACHSRFVTCCAFSIDGTLLASGSMDRIIKIW 720

 Score = 44.7 bits (104), Expect = 7e-05,   Method: Compositional matrix adjust.
 Identities = 56/251 (22%), Positives = 92/251 (36%), Gaps = 9/251 (3%)
 Frame = +1

Query: 119 RIVSSSQDGKVIVWDSFTTNKEHAVTMPCTWVMACAYAPSGCAIACGGLDNKCSVYPLTF 178
            +VS S D  + +W+  T     +       VMA AY+P+G  +  G  +    V+  +F
Sbjct: 103 HLVSGSDDDTICMWEVATQKLVRSYVGHEDSVMALAYSPNGHYLVSGSPNGDLYVWDASF 282

Query: 179 DKNENMAAKKKSVAMHTNYLSACSFTNSDMQILTASGDGTCALWDVESGQLLQSFHGHGA 238
               ++  +   V  H   ++ C F+ +      A    TC L                 
Sbjct: 283 GHCRHLTLR---VDAHDLGVTCCEFSPT-FGTACAENSSTCNL----------------- 399

Query: 239 DVLCLDLAPSETGNTFVSGGCDKKAMVWDMRSG--------QCVQAFETHESDVNSVRYY 290
                            +GG D    +W   +         QC      H   V +  + 
Sbjct: 400 --------------LLATGGKDNLIKLWTFSAQVGSPEVTLQCRDILSGHSDLVMACAFS 537

Query: 291 PSGDAFASGSDDATCRLYDLRADREVAIYSKESIIFG-ASSVDFSLSGRLLFAGYNDYTI 349
           PS    ASGS D + RL+D  + + VA++S E+      +   FS+ G LL +G  D  I
Sbjct: 538 PSSALLASGSFDKSVRLWD--SVKGVALFSIEACHSRFVTCCAFSIDGTLLASGSMDRII 711

Query: 350 NVWDVLKGSRV 360
            +W +   S +
Sbjct: 712 KIWKLTDTSSI 744

 Score = 33.5 bits (75), Expect = 0.14,   Method: Compositional matrix adjust.
 Identities = 23/92 (25%), Positives = 40/92 (43%), Gaps = 6/92 (6%)
 Frame = +1

Query: 92  QFVMKTRRTLKGHGNKVLCMDWCKDKRRIVSSSQDGKVIVWDS------FTTNKEHAVTM 145
           +  ++ R  L GH + V+   +      + S S D  V +WDS      F+    H+  +
Sbjct: 469 EVTLQCRDILSGHSDLVMACAFSPSSALLASGSFDKSVRLWDSVKGVALFSIEACHSRFV 648

Query: 146 PCTWVMACAYAPSGCAIACGGLDNKCSVYPLT 177
            C     CA++  G  +A G +D    ++ LT
Sbjct: 649 TC-----CAFSIDGTLLASGSMDRIIKIWKLT 729
>17598
          Length = 875

 Score = 76.3 bits (186), Expect = 2e-14,   Method: Compositional matrix adjust.
 Identities = 65/267 (24%), Positives = 117/267 (43%), Gaps = 17/267 (6%)
 Frame = +1

Query: 98  RRTLKGHGNKVLCMDWCKDKRRIVSSSQDGKVIVWDSFTTNKEHAVTMPCTWVMACAYAP 157
           RRTL+GH + V  +    D R ++SSS D  + +WD    N            +A A++P
Sbjct: 100 RRTLQGHSHFVSDVSLSADSRYVLSSSWDATLRLWDIKKGNTTRRFISHTRDALAVAFSP 279

Query: 158 SGCAIACGGLDNKCSVY------PLTFDKNENMAAKKKSVAMHTNYLSACSFTNSDMQ-- 209
               IA GG D    ++        T D N            H ++++   F + D +  
Sbjct: 280 DNRQIASGGRDKALKIWNTVGECKFTVDANS-----------HQDWVTCVKF-HQDAKSP 423

Query: 210 -ILTASGDGTCALWDVESGQLLQSFHGHGADVLCLDLAPSETGNTFVSGGCDKKAMVWDM 268
            +++AS D T  +WD ++  L  +F GH   +  +DLA         SG  D   M W++
Sbjct: 424 LVVSASMDKTIKVWDNQTMTLKHTFVGHKTQINAIDLALKTY--YLASGSKDGIVMTWNI 597

Query: 269 RSGQCVQAFETHESDVNSVRYYPSGDAFASGSDDATC--------RLYDLRADREVAIYS 320
           ++G  +   +  + +VN+V++ P+      G+ +           ++ D+RA    A + 
Sbjct: 598 QNGTFLGKIDC-DCEVNAVKFSPNKYWLFVGTSEGIQIWDLPNQKKIKDIRASPIDAQHK 774

Query: 321 KESIIFGASSVDFSLSGRLLFAGYNDY 347
            +      +S+ +  SG  LFAG++ +
Sbjct: 775 SQKKSIACTSLAWDASGHTLFAGFSRW 855

 Score = 45.1 bits (105), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 35/170 (20%), Positives = 69/170 (40%), Gaps = 2/170 (1%)
 Frame = +1

Query: 227 GQLLQSFHGHGADVLCLDLAPSETGNTFVSGGCDKKAMVWDMRSGQCVQAFETHESDVNS 286
           G   ++  GH       D++ S      +S   D    +WD++ G   + F +H  D  +
Sbjct: 91  GGPRRTLQGHSH--FVSDVSLSADSRYVLSSSWDATLRLWDIKKGNTTRRFISHTRDALA 264

Query: 287 VRYYPSGDAFASGSDDATCRLYDLRADREVAIYSKESIIFGASSVDFSLSGR--LLFAGY 344
           V + P     ASG  D   ++++   + +  + +     +  + V F    +  L+ +  
Sbjct: 265 VAFSPDNRQIASGGRDKALKIWNTVGECKFTVDANSHQDW-VTCVKFHQDAKSPLVVSAS 441

Query: 345 NDYTINVWDVLKGSRVSILFGHENRVSTLRVSPDGTAFCSGSWDHTLRVW 394
            D TI VWD    +      GH+ +++ + ++       SGS D  +  W
Sbjct: 442 MDKTIKVWDNQTMTLKHTFVGHKTQINAIDLALKTYYLASGSKDGIVMTW 591

 Score = 42.0 bits (97), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 36/157 (22%), Positives = 69/157 (43%), Gaps = 16/157 (10%)
 Frame = +1

Query: 254 FVSGGCDKKAMVWDMRS----------GQCVQAFETHESDVNSVRYYPSGDAFASGSDDA 303
            + GG DK  +VWD+            G   +  + H   V+ V          S S DA
Sbjct: 10  LIXGGRDKLLIVWDLVPRKDGDEDETWGGPRRTLQGHSHFVSDVSLSADSRYVLSSSWDA 189

Query: 304 TCRLYDLR---ADREVAIYSKESIIFGASSVDFSLSGRLLFAGYNDYTINVWDVLKGSRV 360
           T RL+D++     R    ++++++     +V FS   R + +G  D  + +W+ +   + 
Sbjct: 190 TLRLWDIKKGNTTRRFISHTRDAL-----AVAFSPDNRQIASGGRDKALKIWNTVGECKF 354

Query: 361 SI-LFGHENRVSTLRVSPDGTA--FCSGSWDHTLRVW 394
           ++    H++ V+ ++   D  +    S S D T++VW
Sbjct: 355 TVDANSHQDWVTCVKFHQDAKSPLVVSASMDKTIKVW 465
>02147
          Length = 1547

 Score = 72.8 bits (177), Expect = 2e-13,   Method: Compositional matrix adjust.
 Identities = 61/224 (27%), Positives = 90/224 (40%), Gaps = 41/224 (18%)
 Frame = +2

Query: 212 TASGDGTCALWDVESGQLLQSFHGHGADVLCLDLAPSETGNTFVSGGCDKKAMVWDMRSG 271
           T + D +  +WD E G+ LQ+F  H   V  +D   S  G   ++G  +K   V+D+ + 
Sbjct: 224 TGAADFSAKIWDAEKGEELQTF-SHKHIVKSVDF--SHDGTALLTGSNEKLLKVFDLVNT 394

Query: 272 QC-VQAFETHESDVNSVRYYPSGDAFASGSDDATCRLYDL-------------------- 310
               ++F  H S++    +   G    S SDD T RL+ L                    
Sbjct: 395 DAEPKSFAGHTSNIKGALFLSDGKRIISASDDKTVRLWSLETCQEVQQLTFDTPPTSLTL 574

Query: 311 ------------------RAD--REVAIYSKESIIFGASSVDFSLSGRLLFAGYNDYTIN 350
                             +AD  RE+  +  E+ I   SS     S R   AG  D+ + 
Sbjct: 575 SPDKNTIIVTHSQNIAFYQADTLREMKKFEAEAPI---SSASLHQSERFFVAGGEDFKMY 745

Query: 351 VWDVLKGSRVSILFGHENRVSTLRVSPDGTAFCSGSWDHTLRVW 394
            +D   G  +    GH   V  +R SPDG  + SGS D TLR+W
Sbjct: 746 KFDYETGKEIESFKGHFGPVHCVRFSPDGELYASGSEDGTLRLW 877

 Score = 72.0 bits (175), Expect = 4e-13,   Method: Compositional matrix adjust.
 Identities = 60/258 (23%), Positives = 103/258 (39%), Gaps = 38/258 (14%)
 Frame = +2

Query: 100 TLKGHGNKVLCMDWCKDKRRIVSSSQDGKVIVWDSFTTNKEHAVTMPCTWVMACAYAPSG 159
           T +GH   V      ++  R  + + D    +WD+    +E         V +  ++  G
Sbjct: 158 TFEGHKGAVWGATLNREATRAATGAADFSAKIWDA-EKGEELQTFSHKHIVKSVDFSHDG 334

Query: 160 CAIACGGLDNKCSVYPLTFDKNENMAAKKKSVAMHTNYLSACSFTNSDMQILTASGDGTC 219
            A+  G  +    V+ L      N  A+ KS A HT+ +    F +   +I++AS D T 
Sbjct: 335 TALLTGSNEKLLKVFDLV-----NTDAEPKSFAGHTSNIKGALFLSDGKRIISASDDKTV 499

Query: 220 ALWDVESGQLLQSFHGHGADVLCLDLAPS------------------------------- 248
            LW +E+ Q +Q           L L+P                                
Sbjct: 500 RLWSLETCQEVQQL-TFDTPPTSLTLSPDKNTIIVTHSQNIAFYQADTLREMKKFEAEAP 676

Query: 249 -------ETGNTFVSGGCDKKAMVWDMRSGQCVQAFETHESDVNSVRYYPSGDAFASGSD 301
                  ++   FV+GG D K   +D  +G+ +++F+ H   V+ VR+ P G+ +ASGS+
Sbjct: 677 ISSASLHQSERFFVAGGEDFKMYKFDYETGKEIESFKGHFGPVHCVRFSPDGELYASGSE 856

Query: 302 DATCRLYDLRADREVAIY 319
           D T RL+     R   ++
Sbjct: 857 DGTLRLWQTTIGRTYGLW 910

 Score = 49.7 bits (117), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 34/127 (26%), Positives = 57/127 (44%), Gaps = 1/127 (0%)
 Frame = +2

Query: 270 SGQCVQAFETHESDVNSVRYYPSGDAFASGSDDATCRLYDLRADREVAIYSKESIIFGAS 329
           +G  +  FE H+  V            A+G+ D + +++D     E+  +S + I+    
Sbjct: 140 TGDWIGTFEGHKGAVWGATLNREATRAATGAADFSAKIWDAEKGEELQTFSHKHIV---K 310

Query: 330 SVDFSLSGRLLFAGYNDYTINVWDVLKGSRVSILF-GHENRVSTLRVSPDGTAFCSGSWD 388
           SVDFS  G  L  G N+  + V+D++        F GH + +       DG    S S D
Sbjct: 311 SVDFSHDGTALLTGSNEKLLKVFDLVNTDAEPKSFAGHTSNIKGALFLSDGKRIISASDD 490

Query: 389 HTLRVWA 395
            T+R+W+
Sbjct: 491 KTVRLWS 511

 Score = 28.9 bits (63), Expect = 4.1,   Method: Compositional matrix adjust.
 Identities = 21/74 (28%), Positives = 30/74 (40%), Gaps = 9/74 (12%)
 Frame = +2

Query: 70  EERAKLHDVELHQVAERVEALGQ-FVM--------KTRRTLKGHGNKVLCMDWCKDKRRI 120
           E  A +    LHQ      A G+ F M        K   + KGH   V C+ +  D    
Sbjct: 662 EAEAPISSASLHQSERFFVAGGEDFKMYKFDYETGKEIESFKGHFGPVHCVRFSPDGELY 841

Query: 121 VSSSQDGKVIVWDS 134
            S S+DG + +W +
Sbjct: 842 ASGSEDGTLRLWQT 883
>27465
          Length = 658

 Score = 71.6 bits (174), Expect = 5e-13,   Method: Compositional matrix adjust.
 Identities = 37/122 (30%), Positives = 58/122 (47%)
 Frame = -1

Query: 189 KSVAMHTNYLSACSFTNSDMQILTASGDGTCALWDVESGQLLQSFHGHGADVLCLDLAPS 248
           K +  H   L+  +F  S    +T S D TC +WD  S + L +  GH   V  +    +
Sbjct: 379 KVLRAHILPLTNVAFNKSGSSFITGSYDRTCKIWDTASAEELHTLEGHRNVVYAIAFN-N 203

Query: 249 ETGNTFVSGGCDKKAMVWDMRSGQCVQAFETHESDVNSVRYYPSGDAFASGSDDATCRLY 308
             G+  ++G  DK   +W    G+C      H +++  V + PS    A+GS D TCRL+
Sbjct: 202 PFGDKVITGSFDKTCKLWSTADGKCYHTLRGHTAEIVCVSFNPSSTLIATGSMDTTCRLW 23

Query: 309 DL 310
           D+
Sbjct: 22  DV 17

 Score = 48.9 bits (115), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 29/120 (24%), Positives = 52/120 (43%)
 Frame = -1

Query: 275 QAFETHESDVNSVRYYPSGDAFASGSDDATCRLYDLRADREVAIYSKESIIFGASSVDFS 334
           +    H   + +V +  SG +F +GS D TC+++D  +  E+        +  A + +  
Sbjct: 379 KVLRAHILPLTNVAFNKSGSSFITGSYDRTCKIWDTASAEELHTLEGHRNVVYAIAFNNP 200

Query: 335 LSGRLLFAGYNDYTINVWDVLKGSRVSILFGHENRVSTLRVSPDGTAFCSGSWDHTLRVW 394
              +++  G  D T  +W    G     L GH   +  +  +P  T   +GS D T R+W
Sbjct: 199 FGDKVI-TGSFDKTCKLWSTADGKCYHTLRGHTAEIVCVSFNPSSTLIATGSMDTTCRLW 23

 Score = 44.3 bits (103), Expect = 9e-05,   Method: Compositional matrix adjust.
 Identities = 34/131 (25%), Positives = 54/131 (41%), Gaps = 1/131 (0%)
 Frame = -1

Query: 99  RTLKGHGNKVLCMDWCKDKRRIVSSSQDGKVIVWDSFTTNKEHAVTMPCTWVMACAYA-P 157
           + L+ H   +  + + K     ++ S D    +WD+ +  + H +      V A A+  P
Sbjct: 379 KVLRAHILPLTNVAFNKSGSSFITGSYDRTCKIWDTASAEELHTLEGHRNVVYAIAFNNP 200

Query: 158 SGCAIACGGLDNKCSVYPLTFDKNENMAAKKKSVAMHTNYLSACSFTNSDMQILTASGDG 217
            G  +  G  D  C ++     K  +      ++  HT  +   SF  S   I T S D 
Sbjct: 199 FGDKVITGSFDKTCKLWSTADGKCYH------TLRGHTAEIVCVSFNPSSTLIATGSMDT 38

Query: 218 TCALWDVESGQ 228
           TC LWDVE  Q
Sbjct: 37  TCRLWDVEKAQ 5
>00561
          Length = 1003

 Score = 71.2 bits (173), Expect = 6e-13,   Method: Compositional matrix adjust.
 Identities = 56/193 (29%), Positives = 89/193 (46%), Gaps = 8/193 (4%)
 Frame = -3

Query: 210 ILTASGDGTCALW------DVESGQLLQSFHGHGADVLCLDLAPSETGNTFVSGGCDKKA 263
           I++AS D T  +W      D   G   +  +GH       D+  S  GN  +SG  D+  
Sbjct: 965 IISASRDKTLIVWKLTRDEDTNYGYPQKRLYGHSH--FISDVVLSSDGNYALSGSWDQTL 792

Query: 264 MVWDMRSGQCVQAFETHESDVNSVRYYPSGDAFASGSDDATCRLYDLRADREVAIYSKES 323
            +WD+ +G+  + FE H  DV SV +        SGS D T +L++  A+ +  I  ++ 
Sbjct: 791 RLWDLAAGKTTRRFEGHTKDVLSVAFSADNRQIVSGSRDKTIKLWNTLAECKFTI-QEDG 615

Query: 324 IIFGASSVDFSL--SGRLLFAGYNDYTINVWDVLKGSRVSILFGHENRVSTLRVSPDGTA 381
                S V FS   S  ++ +   D T+ VW++      +   GH   ++T+ VSPDG+ 
Sbjct: 614 HTDWVSCVRFSPNHSNPIIVSCGWDRTVKVWNLANCKLKNNHHGHNGYLNTVTVSPDGSL 435

Query: 382 FCSGSWDHTLRVW 394
             SG  D    +W
Sbjct: 434 CTSGGKDSKALLW 396

 Score = 64.3 bits (155), Expect = 7e-11,   Method: Compositional matrix adjust.
 Identities = 52/236 (22%), Positives = 90/236 (38%), Gaps = 43/236 (18%)
 Frame = -3

Query: 162 IACGGLDNKCSVYPLTFDKNENMAAKKKSVAMHTNYLSACSFTNSDMQILTASGDGTCAL 221
           I     D    V+ LT D++ N    +K +  H++++S    ++     L+ S D T  L
Sbjct: 965 IISASRDKTLIVWKLTRDEDTNYGYPQKRLYGHSHFISDVVLSSDGNYALSGSWDQTLRL 786

Query: 222 WDVESGQLLQSFHGHGADVL---------------------------------------- 241
           WD+ +G+  + F GH  DVL                                        
Sbjct: 785 WDLAAGKTTRRFEGHTKDVLSVAFSADNRQIVSGSRDKTIKLWNTLAECKFTIQEDGHTD 606

Query: 242 ---CLDLAPSETGNTFVSGGCDKKAMVWDMRSGQCVQAFETHESDVNSVRYYPSGDAFAS 298
              C+  +P+ +    VS G D+   VW++ + +       H   +N+V   P G    S
Sbjct: 605 WVSCVRFSPNHSNPIIVSCGWDRTVKVWNLANCKLKNNHHGHNGYLNTVTVSPDGSLCTS 426

Query: 299 GSDDATCRLYDLRADREVAIYSKESIIFGASSVDFSLSGRLLFAGYNDYTINVWDV 354
           G  D+   L+DL   + +       II   +++ FS +   L   Y   +I +WD+
Sbjct: 425 GGKDSKALLWDLNDGKNLYTLEHNDII---NALCFSPNRYWLCVAYGP-SIKIWDL 270

 Score = 52.0 bits (123), Expect = 5e-07,   Method: Compositional matrix adjust.
 Identities = 46/201 (22%), Positives = 84/201 (41%), Gaps = 4/201 (1%)
 Frame = -3

Query: 96  KTRRTLKGHGNKVLCMDWCKDKRRIVSSSQDGKVIVWDSFT----TNKEHAVTMPCTWVM 151
           KT R  +GH   VL + +  D R+IVS S+D  + +W++      T +E   T    WV 
Sbjct: 767 KTTRRFEGHTKDVLSVAFSADNRQIVSGSRDKTIKLWNTLAECKFTIQEDGHT---DWVS 597

Query: 152 ACAYAPSGCAIACGGLDNKCSVYPLTFDKNENMAAKKKSVAMHTNYLSACSFTNSDMQIL 211
              ++P+                                   H+N +           I+
Sbjct: 596 CVRFSPN-----------------------------------HSNPI-----------IV 555

Query: 212 TASGDGTCALWDVESGQLLQSFHGHGADVLCLDLAPSETGNTFVSGGCDKKAMVWDMRSG 271
           +   D T  +W++ + +L  + HGH   +  + ++P   G+   SGG D KA++WD+  G
Sbjct: 554 SCGWDRTVKVWNLANCKLKNNHHGHNGYLNTVTVSPD--GSLCTSGGKDSKALLWDLNDG 381

Query: 272 QCVQAFETHESDVNSVRYYPS 292
           + +   E H   +N++ + P+
Sbjct: 380 KNLYTLE-HNDIINALCFSPN 321

 Score = 33.1 bits (74), Expect = 0.20,   Method: Compositional matrix adjust.
 Identities = 14/25 (56%), Positives = 18/25 (72%)
 Frame = -2

Query: 330 SVDFSLSGRLLFAGYNDYTINVWDV 354
           S+ +S  G+ LFAGY+D TI VW V
Sbjct: 192 SLAWSTDGQTLFAGYSDNTIRVWQV 118
>12806
          Length = 961

 Score = 67.4 bits (163), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 51/200 (25%), Positives = 88/200 (44%), Gaps = 8/200 (4%)
 Frame = +3

Query: 98  RRTLKGHGNKVLCMDWCKDKRRIVSSSQDGKVIVWDSFTTNKEHAVTMPCTWVMACAYAP 157
           R+TL GH + +  +    D R  +SSS D  + +WD    +           V+  A++P
Sbjct: 144 RKTLTGHSHFISDLALSADSRFALSSSWDATLRLWDIKKGSTTSRFINHTRDVLTVAFSP 323

Query: 158 SGCAIACGGLDNKCSVYPL------TFDKNENMAAKKKSVAMHTNYLSACSF--TNSDMQ 209
               IA GG D    ++ +      T D N            HT++++   F     +  
Sbjct: 324 DNRQIASGGRDKNLKIWNIMGECKYTVDANA-----------HTDWVTCVRFHQDTKNPI 470

Query: 210 ILTASGDGTCALWDVESGQLLQSFHGHGADVLCLDLAPSETGNTFVSGGCDKKAMVWDMR 269
           +++AS D T  +WD  +  L  +F GH A +  LD++     N  VSG  D  AM W++ 
Sbjct: 471 VVSASNDKTIKVWDNHTMTLKNTFVGHKAQITALDMST----NYLVSGSKDGIAMTWNVA 638

Query: 270 SGQCVQAFETHESDVNSVRY 289
            G  V   +  +  +N++++
Sbjct: 639 EGSFVGKIDC-DDQINAIKF 695

 Score = 64.7 bits (156), Expect = 6e-11,   Method: Compositional matrix adjust.
 Identities = 51/207 (24%), Positives = 87/207 (42%), Gaps = 8/207 (3%)
 Frame = +3

Query: 162 IACGGLDNKCSVYPL----TFDKNENMAAKKKSVAMHTNYLSACSFTNSDMQILTASGDG 217
           +  GG DN   V+ L      D+++     +K++  H++++S  + +      L++S D 
Sbjct: 54  LISGGRDNNIIVWDL*PKKDGDEDQTWGVPRKTLTGHSHFISDLALSADSRFALSSSWDA 233

Query: 218 TCALWDVESGQLLQSFHGHGADVLCLDLAPSETGNTFVSGGCDKKAMVWDMRSGQCVQAF 277
           T  LWD++ G     F  H  DVL +  +P        SGG DK   +W++  G+C    
Sbjct: 234 TLRLWDIKKGSTTSRFINHTRDVLTVAFSPDN--RQIASGGRDKNLKIWNIM-GECKYTV 404

Query: 278 E--THESDVNSVRYY--PSGDAFASGSDDATCRLYDLRADREVAIYSKESIIFGASSVDF 333
           +   H   V  VR++         S S+D T +++    D          +   A     
Sbjct: 405 DANAHTDWVTCVRFHQDTKNPIVVSASNDKTIKVW----DNHTMTLKNTFVGHKAQITAL 572

Query: 334 SLSGRLLFAGYNDYTINVWDVLKGSRV 360
            +S   L +G  D     W+V +GS V
Sbjct: 573 DMSTNYLVSGSKDGIAMTWNVAEGSFV 653

 Score = 49.3 bits (116), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 37/153 (24%), Positives = 66/153 (43%), Gaps = 2/153 (1%)
 Frame = +3

Query: 244 DLAPSETGNTFVSGGCDKKAMVWDMRSGQCVQAFETHESDVNSVRYYPSGDAFASGSDDA 303
           DLA S      +S   D    +WD++ G     F  H  DV +V + P     ASG  D 
Sbjct: 180 DLALSADSRFALSSSWDATLRLWDIKKGSTTSRFINHTRDVLTVAFSPDNRQIASGGRDK 359

Query: 304 TCRLYDLRADREVAIYSKESIIFGASSVDFSLSGR--LLFAGYNDYTINVWDVLKGSRVS 361
             +++++  + +  + +     +  + V F    +  ++ +  ND TI VWD    +  +
Sbjct: 360 NLKIWNIMGECKYTVDANAHTDW-VTCVRFHQDTKNPIVVSASNDKTIKVWDNHTMTLKN 536

Query: 362 ILFGHENRVSTLRVSPDGTAFCSGSWDHTLRVW 394
              GH+ +++ L +S +     SGS D     W
Sbjct: 537 TFVGHKAQITALDMSTN--YLVSGSKDGIAMTW 629

 Score = 44.3 bits (103), Expect = 8e-05,   Method: Compositional matrix adjust.
 Identities = 22/66 (33%), Positives = 30/66 (45%)
 Frame = +3

Query: 329 SSVDFSLSGRLLFAGYNDYTINVWDVLKGSRVSILFGHENRVSTLRVSPDGTAFCSGSWD 388
           S +  S   R   +   D T+ +WD+ KGS  S    H   V T+  SPD     SG  D
Sbjct: 177 SDLALSADSRFALSSSWDATLRLWDIKKGSTTSRFINHTRDVLTVAFSPDNRQIASGGRD 356

Query: 389 HTLRVW 394
             L++W
Sbjct: 357 KNLKIW 374

 Score = 40.8 bits (94), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 36/154 (23%), Positives = 67/154 (43%), Gaps = 13/154 (8%)
 Frame = +3

Query: 254 FVSGGCDKKAMVWDM---RSGQCVQAFETHESDVNSVRYYPSGDAFA-------SGSDDA 303
            +SGG D   +VWD+   + G   Q +      +    ++ S  A +       S S DA
Sbjct: 54  LISGGRDNNIIVWDL*PKKDGDEDQTWGVPRKTLTGHSHFISDLALSADSRFALSSSWDA 233

Query: 304 TCRLYDLRADREVAIYSKESIIFGASSVDFSLSGRLLFAGYNDYTINVWDVLKGSRVSI- 362
           T RL+D++     + +   +      +V FS   R + +G  D  + +W+++   + ++ 
Sbjct: 234 TLRLWDIKKGSTTSRFINHT--RDVLTVAFSPDNRQIASGGRDKNLKIWNIMGECKYTVD 407

Query: 363 LFGHENRVSTLRVSPD--GTAFCSGSWDHTLRVW 394
              H + V+ +R   D       S S D T++VW
Sbjct: 408 ANAHTDWVTCVRFHQDTKNPIVVSASNDKTIKVW 509
>02090
          Length = 1841

 Score = 64.7 bits (156), Expect = 6e-11,   Method: Compositional matrix adjust.
 Identities = 37/145 (25%), Positives = 68/145 (46%)
 Frame = -3

Query: 216  DGTCALWDVESGQLLQSFHGHGADVLCLDLAPSETGNTFVSGGCDKKAMVWDMRSGQCVQ 275
            DG  A+WD+ +  L++ F GH     C+D++P   G    +GG D     WD+R G+ +Q
Sbjct: 1563 DGNIAVWDLHNQTLVRQFQGHTDGASCIDISPD--GTKLWTGGLDNTVRSWDLREGRQLQ 1390

Query: 276  AFETHESDVNSVRYYPSGDAFASGSDDATCRLYDLRADREVAIYSKESIIFGASSVDFSL 335
              +   S + S+ Y P+G+  A G + +   +       +  ++  ES +    S+ F+ 
Sbjct: 1389 QHD-FSSQIFSLGYCPTGEWLAVGMESSNVEVLHHSKPDKYQLHLHESCVL---SLKFAY 1222

Query: 336  SGRLLFAGYNDYTINVWDVLKGSRV 360
             G+   +   D  +N W    G+ +
Sbjct: 1221 CGKWFVSTGKDNLLNAWRTPYGASI 1147

 Score = 53.5 bits (127), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 45/177 (25%), Positives = 72/177 (40%)
 Frame = -3

Query: 218  TCALWDVESGQLLQSFHGHGADVLCLDLAPSETGNTFVSGGCDKKAMVWDMRSGQCVQAF 277
            T ++WD+ +           +   C  LA S  G    S   D    VWD+ +   V+ F
Sbjct: 1689 TLSIWDLATPTPRIKAELTSSAPACYALAISPDGKVCFSCCSDGNIAVWDLHNQTLVRQF 1510

Query: 278  ETHESDVNSVRYYPSGDAFASGSDDATCRLYDLRADREVAIYSKESIIFGASSVDFSLSG 337
            + H    + +   P G    +G  D T R +DLR  R++  +   S IF   S+ +  +G
Sbjct: 1509 QGHTDGASCIDISPDGTKLWTGGLDNTVRSWDLREGRQLQQHDFSSQIF---SLGYCPTG 1339

Query: 338  RLLFAGYNDYTINVWDVLKGSRVSILFGHENRVSTLRVSPDGTAFCSGSWDHTLRVW 394
              L  G     + V    K  +  +   HE+ V +L+ +  G  F S   D+ L  W
Sbjct: 1338 EWLAVGMESSNVEVLHHSKPDKYQLHL-HESCVLSLKFAYCGKWFVSTGKDNLLNAW 1171

 Score = 28.9 bits (63), Expect = 3.9,   Method: Compositional matrix adjust.
 Identities = 34/171 (19%), Positives = 65/171 (38%), Gaps = 1/171 (0%)
 Frame = -3

Query: 99   RTLKGHGNKVLCMDWCKDKRRIVSSSQDGKVIVWDSFTTNKEHAVTMPCTWVMACAYAPS 158
            R  +GH +   C+D   D  ++ +   D  V  WD     ++       + + +  Y P+
Sbjct: 1518 RQFQGHTDGASCIDISPDGTKLWTGGLDNTVRSWD-LREGRQLQQHDFSSQIFSLGYCPT 1342

Query: 159  GCAIACGGLDNKCSVYPLTFDKNENMAAKKKSVAMHTNYLSACSFTNSDMQILTASGDGT 218
            G  +A G   +   V         +    K  + +H + + +  F       ++   D  
Sbjct: 1341 GEWLAVGMESSNVEVL-------HHSKPDKYQLHLHESCVLSLKFAYCGKWFVSTGKDNL 1183

Query: 219  CALWDVESG-QLLQSFHGHGADVLCLDLAPSETGNTFVSGGCDKKAMVWDM 268
               W    G  + QS     + VL  D+A  +     V+G  DKKA ++++
Sbjct: 1182 LNAWRTPYGASIFQS--KESSSVLSCDIAADD--KYIVTGSGDKKATLYEV 1042

 Score = 28.1 bits (61), Expect = 6.3,   Method: Compositional matrix adjust.
 Identities = 40/163 (24%), Positives = 60/163 (36%), Gaps = 1/163 (0%)
 Frame = -3

Query: 194  HTNYLSACSFTNSDMQILTASGDGTCALWDVESGQLLQSFHGHGADVLCLDLAPSETGNT 253
            HT+  S    +    ++ T   D T   WD+  G+ LQ  H   + +  L   P  TG  
Sbjct: 1503 HTDGASCIDISPDGTKLWTGGLDNTVRSWDLREGRQLQQ-HDFSSQIFSLGYCP--TGEW 1333

Query: 254  FVSGGCDKKAMVWDMRSGQCVQAFETHESDVNSVRYYPSGDAFASGSDDATCRLYDLRAD 313
               G       V         Q    HES V S+++   G  F S   D    L   R  
Sbjct: 1332 LAVGMESSNVEVLHHSKPDKYQ-LHLHESCVLSLKFAYCGKWFVSTGKDNL--LNAWRTP 1162

Query: 314  REVAIY-SKESIIFGASSVDFSLSGRLLFAGYNDYTINVWDVL 355
               +I+ SKES      S D +   + +  G  D    +++V+
Sbjct: 1161 YGASIFQSKES--SSVLSCDIAADDKYIVTGSGDKKATLYEVI 1039
>19949
          Length = 903

 Score = 62.8 bits (151), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 45/158 (28%), Positives = 73/158 (46%), Gaps = 3/158 (1%)
 Frame = +2

Query: 240 VLCLDLAPSETGNTFVSGGCDKKAMVWDMRSGQCVQAFETHESDVNSVRYYPSGDAFASG 299
           V  LD  P   G    SG  D    +WD+R   C+  ++ H   V  +R+ P G   AS 
Sbjct: 2   VKSLDFHP--YGAYTASGSMDCNVKLWDIRRKGCIYTYKGHTGCVCCLRFSPDGRWIASA 175

Query: 300 SDDATCRLYDLRADR---EVAIYSKESIIFGASSVDFSLSGRLLFAGYNDYTINVWDVLK 356
           S+D   +L+DL A +   ++ ++         ++++F     LL +G  D T+  WD+  
Sbjct: 176 SEDGLVKLWDLTAGKLLTDLKLHRD-----AVNTIEFHPHEFLLASGSADRTVKFWDLET 340

Query: 357 GSRVSILFGHENRVSTLRVSPDGTAFCSGSWDHTLRVW 394
              +S      N + ++   PDG    SGS D TL+V+
Sbjct: 341 FQLISTTEPEANSIRSILFHPDGVCLYSGSKD-TLKVY 451

 Score = 62.0 bits (149), Expect = 4e-10,   Method: Compositional matrix adjust.
 Identities = 43/149 (28%), Positives = 70/149 (46%), Gaps = 4/149 (2%)
 Frame = +2

Query: 212 TASGDGTC--ALWDVESGQLLQSFHGHGADVLCLDLAPSETGNTFVSGGCDKKAMVWDMR 269
           TASG   C   LWD+     + ++ GH   V CL  +P   G    S   D    +WD+ 
Sbjct: 38  TASGSMDCNVKLWDIRRKGCIYTYKGHTGCVCCLRFSPD--GRWIASASEDGLVKLWDLT 211

Query: 270 SGQCVQAFETHESDVNSVRYYPSGDAFASGSDDATCRLYDLRADREVAIYSKESIIFGAS 329
           +G+ +   + H   VN++ ++P     ASGS D T + +DL   + ++    E+      
Sbjct: 212 AGKLLTDLKLHRDAVNTIEFHPHEFLLASGSADRTVKFWDLETFQLISTTEPEA--NSIR 385

Query: 330 SVDFSLSGRLLFAGYNDYTINV--WDVLK 356
           S+ F   G  L++G  D T+ V  W+ L+
Sbjct: 386 SILFHPDGVCLYSGSKD-TLKVYHWEPLE 469

 Score = 61.6 bits (148), Expect = 5e-10,   Method: Compositional matrix adjust.
 Identities = 54/202 (26%), Positives = 85/202 (42%)
 Frame = +2

Query: 150 VMACAYAPSGCAIACGGLDNKCSVYPLTFDKNENMAAKKKSVAMHTNYLSACSFTNSDMQ 209
           V +  + P G   A G +D  C+V      +   +   K     HT  +    F+     
Sbjct: 2   VKSLDFHPYGAYTASGSMD--CNVKLWDIRRKGCIYTYKG----HTGCVCCLRFSPDGRW 163

Query: 210 ILTASGDGTCALWDVESGQLLQSFHGHGADVLCLDLAPSETGNTFVSGGCDKKAMVWDMR 269
           I +AS DG   LWD+ +G+LL     H   V  ++  P E      SG  D+    WD+ 
Sbjct: 164 IASASEDGLVKLWDLTAGKLLTDLKLHRDAVNTIEFHPHEF--LLASGSADRTVKFWDLE 337

Query: 270 SGQCVQAFETHESDVNSVRYYPSGDAFASGSDDATCRLYDLRADREVAIYSKESIIFGAS 329
           + Q +   E   + + S+ ++P G    SGS D T ++Y       + +Y   S+ +G  
Sbjct: 338 TFQLISTTEPEANSIRSILFHPDGVCLYSGSKD-TLKVYHWEP---LELYDTVSVPWG-Q 502

Query: 330 SVDFSLSGRLLFAGYNDYTINV 351
             D S+S   L  G + Y  NV
Sbjct: 503 VCDMSISNTQLI-GASFYKTNV 565

 Score = 33.9 bits (76), Expect = 0.12,   Method: Compositional matrix adjust.
 Identities = 28/101 (27%), Positives = 41/101 (40%), Gaps = 4/101 (3%)
 Frame = +2

Query: 100 TLKGHGNKVLCMDWCKDKRRIVSSSQDGKVIVWDSFTTNKEHAVTMPCTWVMACAYAPSG 159
           T KGH   V C+ +  D R I S+S+DG V +WD         + +    V    + P  
Sbjct: 104 TYKGHTGCVCCLRFSPDGRWIASASEDGLVKLWDLTAGKLLTDLKLHRDAVNTIEFHPHE 283

Query: 160 CAIACGGLDNKCSVYPL-TFD---KNENMAAKKKSVAMHTN 196
             +A G  D     + L TF      E  A   +S+  H +
Sbjct: 284 FLLASGSADRTVKFWDLETFQLISTTEPEANSIRSILFHPD 406
>12960
          Length = 550

 Score = 61.2 bits (147), Expect = 7e-10,   Method: Compositional matrix adjust.
 Identities = 40/144 (27%), Positives = 65/144 (45%), Gaps = 5/144 (3%)
 Frame = +2

Query: 180 KNENMA-----AKKKSVAMHTNYLSACSFTNSDMQILTASGDGTCALWDVESGQLLQSFH 234
           +N NM       K+ ++      + A  F+      +T   D +  LW+      L+++ 
Sbjct: 113 QNTNMKFELPDRKEVTINCKQQAVRAVRFSVDSRYCMTCGSDKSVKLWNPHRELFLKTYI 292

Query: 235 GHGADVLCLDLAPSETGNTFVSGGCDKKAMVWDMRSGQCVQAFETHESDVNSVRYYPSGD 294
           GHG +VL  D   S   +   SGG DK  +++D+ SGQ ++ +  H   VN V++     
Sbjct: 293 GHGHEVL--DAQGSGDNSQICSGGIDKTVVLFDVASGQALRKYRDHAGTVNCVKFNEEST 466

Query: 295 AFASGSDDATCRLYDLRADREVAI 318
              SGS D T R +D R+     I
Sbjct: 467 VILSGSLDNTVRAWDTRSRSHTPI 538

 Score = 32.3 bits (72), Expect = 0.38,   Method: Compositional matrix adjust.
 Identities = 22/79 (27%), Positives = 38/79 (48%), Gaps = 2/79 (2%)
 Frame = +2

Query: 318 IYSKESIIFGASSVDFSLSG--RLLFAGYNDYTINVWDVLKGSRVSILFGHENRVSTLRV 375
           ++ K  I  G   +D   SG    + +G  D T+ ++DV  G  +     H   V+ ++ 
Sbjct: 272 LFLKTYIGHGHEVLDAQGSGDNSQICSGGIDKTVVLFDVASGQALRKYRDHAGTVNCVKF 451

Query: 376 SPDGTAFCSGSWDHTLRVW 394
           + + T   SGS D+T+R W
Sbjct: 452 NEESTVILSGSLDNTVRAW 508
>03156
          Length = 1014

 Score = 61.2 bits (147), Expect = 7e-10,   Method: Compositional matrix adjust.
 Identities = 49/194 (25%), Positives = 81/194 (41%), Gaps = 9/194 (4%)
 Frame = +1

Query: 210 ILTASGDGTCALWDVESGQLLQSFHGHGADVLCLDLAPSETGNTFV-SGGCDKKAMVWDM 268
           + +AS D T  +W   +   ++ F GH   V  + L    T NT + SG  D    +WD+
Sbjct: 100 MFSASRDKTIKMWQRGNSHSIRDFIGHDMVVTAIHL---NTDNTLLCSGSRDNTVRIWDV 270

Query: 269 RSGQCVQAFETHESDVNSVRYYPSGDAFASGSDDATCRLYDLRADREVAIYSKESIIFGA 328
            +G C++     ++ V  V++ P         +D   R+YD R    V  ++K+  I   
Sbjct: 271 ETGACLRQNNIPQNLVTDVKWLPGSHLIIQAGEDKEVRIYDSRTLGIVRSFTKKQYI--Q 444

Query: 329 SSVDFSLSGRLLFAGYNDYTIN-----VWDVLKGSRVSILFGHENRVSTLRVSP---DGT 380
            S D +  G+      N +  N     +W +  GS  +   GH   +      P   D T
Sbjct: 445 MSCDVTADGQFCLTCSNGFGGNGCEATLWQLSDGSIQNEFKGHREAIEACLFLPSNQDMT 624

Query: 381 AFCSGSWDHTLRVW 394
              + S D ++RVW
Sbjct: 625 LIATASRDCSVRVW 666

 Score = 47.0 bits (110), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 59/235 (25%), Positives = 86/235 (36%), Gaps = 22/235 (9%)
 Frame = +1

Query: 66  GKLEEERAKLHDVELHQVAERVEALGQFVMKTRRTLK--------------GHGNKVLCM 111
           G+LE+ R   HD E+ +V       G F     +T+K              GH   V  +
Sbjct: 25  GRLED-RWTGHDREITKVCYGASCNGMFSASRDKTIKMWQRGNSHSIRDFIGHDMVVTAI 201

Query: 112 DWCKDKRRIVSSSQDGKVIVWDSFTTNKEHAVTMPCTWVMACAYAPSGCAIACGGLDNKC 171
               D   + S S+D  V +WD  T        +P   V    + P    I   G D + 
Sbjct: 202 HLNTDNTLLCSGSRDNTVRIWDVETGACLRQNNIPQNLVTDVKWLPGSHLIIQAGEDKEV 381

Query: 172 SVYPLTFDKNENMAAKKKSVAMHTNYLSACSFTNSDMQILTAS----GDGTCA-LWDVES 226
            +Y            KK+ + M      +C  T      LT S    G+G  A LW +  
Sbjct: 382 RIYDSRTLGIVRSFTKKQYIQM------SCDVTADGQFCLTCSNGFGGNGCEATLWQLSD 543

Query: 227 GQLLQSFHGHGADV-LCLDLAPSETGNTFVSGGCDKKAMVWDMRSGQCV--QAFE 278
           G +   F GH   +  CL L  ++      +   D    VW+M + +CV  Q FE
Sbjct: 544 GSIQNEFKGHREAIEACLFLPSNQDMTLIATASRDCSVRVWNMFTKECVCEQNFE 708
>01327
          Length = 2215

 Score = 60.8 bits (146), Expect = 9e-10,   Method: Compositional matrix adjust.
 Identities = 49/194 (25%), Positives = 81/194 (41%), Gaps = 9/194 (4%)
 Frame = +3

Query: 210 ILTASGDGTCALWDVESGQLLQSFHGHGADVLCLDLAPSETGNTFV-SGGCDKKAMVWDM 268
           + +AS D T  +W   +   ++ F GH   V  + L    T NT + SG  D    +WD+
Sbjct: 210 MFSASRDKTIKMWQRGNSHSIRDFIGHDMVVTAIHL---NTDNTLLCSGSRDNTVRIWDV 380

Query: 269 RSGQCVQAFETHESDVNSVRYYPSGDAFASGSDDATCRLYDLRADREVAIYSKESIIFGA 328
            +G C++     ++ V  V++ P         +D   R+YD R    V  ++K+  I   
Sbjct: 381 ETGACLRQNNIPQNLVTDVKWLPGSHLIIQAGEDKEVRIYDSRTLGIVRSFTKKQYI--Q 554

Query: 329 SSVDFSLSGRLLFAGYNDYTIN-----VWDVLKGSRVSILFGHENRVSTLRVSP---DGT 380
            S D +  G+      N +  N     +W +  GS  +   GH   +      P   D T
Sbjct: 555 MSCDVTADGQFCLTCSNGFGGNGCEATLWQLSDGSIQNEFKGHREAIEACLFLPSNQDMT 734

Query: 381 AFCSGSWDHTLRVW 394
              + S D ++RVW
Sbjct: 735 LIATASRDCSVRVW 776

 Score = 47.0 bits (110), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 59/236 (25%), Positives = 86/236 (36%), Gaps = 22/236 (9%)
 Frame = +3

Query: 65  KGKLEEERAKLHDVELHQVAERVEALGQFVMKTRRTLK--------------GHGNKVLC 110
            G+LE+ R   HD E+ +V       G F     +T+K              GH   V  
Sbjct: 132 NGRLED-RWTGHDREITKVCYGASCNGMFSASRDKTIKMWQRGNSHSIRDFIGHDMVVTA 308

Query: 111 MDWCKDKRRIVSSSQDGKVIVWDSFTTNKEHAVTMPCTWVMACAYAPSGCAIACGGLDNK 170
           +    D   + S S+D  V +WD  T        +P   V    + P    I   G D +
Sbjct: 309 IHLNTDNTLLCSGSRDNTVRIWDVETGACLRQNNIPQNLVTDVKWLPGSHLIIQAGEDKE 488

Query: 171 CSVYPLTFDKNENMAAKKKSVAMHTNYLSACSFTNSDMQILTAS----GDGTCA-LWDVE 225
             +Y            KK+ + M      +C  T      LT S    G+G  A LW + 
Sbjct: 489 VRIYDSRTLGIVRSFTKKQYIQM------SCDVTADGQFCLTCSNGFGGNGCEATLWQLS 650

Query: 226 SGQLLQSFHGHGADV-LCLDLAPSETGNTFVSGGCDKKAMVWDMRSGQCV--QAFE 278
            G +   F GH   +  CL L  ++      +   D    VW+M + +CV  Q FE
Sbjct: 651 DGSIQNEFKGHREAIEACLFLPSNQDMTLIATASRDCSVRVWNMFTKECVCEQNFE 818

 Score = 46.2 bits (108), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 31/107 (28%), Positives = 48/107 (44%), Gaps = 10/107 (9%)
 Frame = +3

Query: 298 SGSDDATCRLYDLRA----------DREVAIYSKESIIFGASSVDFSLSGRLLFAGYNDY 347
           SGS D +  LYD +           DRE+       + +GAS          +F+   D 
Sbjct: 90  SGSKDKSVVLYDYQNGRLEDRWTGHDREIT-----KVCYGASC-------NGMFSASRDK 233

Query: 348 TINVWDVLKGSRVSILFGHENRVSTLRVSPDGTAFCSGSWDHTLRVW 394
           TI +W       +    GH+  V+ + ++ D T  CSGS D+T+R+W
Sbjct: 234 TIKMWQRGNSHSIRDFIGHDMVVTAIHLNTDNTLLCSGSRDNTVRIW 374
>26107
          Length = 1338

 Score = 58.9 bits (141), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 64/256 (25%), Positives = 93/256 (36%), Gaps = 55/256 (21%)
 Frame = -3

Query: 194  HTNYLSACSFTNSDMQILTASGDGTCALWDVESGQLLQSFHGHGADVLCLDLAPSETGNT 253
            H N +   S+ ++D Q LTASGD T ALWDVE+   + +F GH   V  +   PS     
Sbjct: 1090 HNNAVFDYSWISNDSQCLTASGDQTVALWDVETTTKVTTFIGHKCSVRSVASCPSSPAQC 911

Query: 254  FVSGGCDKKAMVWDMRSGQ------CVQAFET-----HES-------------------- 282
              SG  D   M+WD R  +      C Q  +      H+S                    
Sbjct: 910  -ASGARDGHIMLWDSRVNKKREHQPCSQVHQVCPQSGHQSKPAKHRRIHRAAGPKGVMDT 734

Query: 283  --DVNSVRYYPSGDAFASGSDDATCRLYDLRADREVAIYSKESIIFGASSVDFSLSGRL- 339
               V  V Y       +SG++D   +++D R       Y+  +         F   G + 
Sbjct: 733  QQSVTCVLYQTDNLIISSGANDGCVKMWDTR-----KWYTNTTTSLPVPVHTFDYPGHMR 569

Query: 340  ----------------LFAGYND---YTINVWDVLKGSRVSILFGHENRVSTLR--VSPD 378
                            LF  Y D   Y   +    +  +  +  GH N    +R  +SPD
Sbjct: 568  RLKGIVTMCMDPWKSQLFVSYTDNKVYRYQLAGQYREPQEYVYAGHRNDTFFVRCAISPD 389

Query: 379  GTAFCSGSWDHTLRVW 394
            G    SGS  +T  +W
Sbjct: 388  GKYLLSGSGRNTGVIW 341

 Score = 28.1 bits (61), Expect = 5.6,   Method: Compositional matrix adjust.
 Identities = 52/256 (20%), Positives = 91/256 (35%), Gaps = 48/256 (18%)
 Frame = -3

Query: 103  GHGNKVLCMDWCKDKRRIVSSSQDGKVIVWDSFTTNKEHA-VTMPCTW--VMACAYAPSG 159
             H N V    W  +  + +++S D  V +WD  TT K    +   C+   V +C  +P+ 
Sbjct: 1093 AHNNAVFDYSWISNDSQCLTASGDQTVALWDVETTTKVTTFIGHKCSVRSVASCPSSPAQ 914

Query: 160  CAIACGGLDNKCSVYPLTFDK------------------NENMAAKKKSV--------AM 193
            C  A G  D    ++    +K                  +++  AK + +         M
Sbjct: 913  C--ASGARDGHIMLWDSRVNKKREHQPCSQVHQVCPQSGHQSKPAKHRRIHRAAGPKGVM 740

Query: 194  HTNYLSACSFTNSDMQILTA-SGDGTCALWDVE------SGQLLQSFH-----GH----- 236
             T     C    +D  I+++ + DG   +WD        +  L    H     GH     
Sbjct: 739  DTQQSVTCVLYQTDNLIISSGANDGCVKMWDTRKWYTNTTTSLPVPVHTFDYPGHMRRLK 560

Query: 237  GADVLCLDLAPSETGNTFVSGGCDKKAMVWDMRSGQCVQAFETHESDVNSVR--YYPSGD 294
            G   +C+D   S+   ++      +  +    R  Q    +  H +D   VR    P G 
Sbjct: 559  GIVTMCMDPWKSQLFVSYTDNKVYRYQLAGQYREPQ-EYVYAGHRNDTFFVRCAISPDGK 383

Query: 295  AFASGSDDATCRLYDL 310
               SGS   T  ++++
Sbjct: 382  YLLSGSGRNTGVIWEV 335
>17602
          Length = 481

 Score = 58.5 bits (140), Expect = 5e-09,   Method: Compositional matrix adjust.
 Identities = 35/133 (26%), Positives = 61/133 (45%), Gaps = 3/133 (2%)
 Frame = +3

Query: 265 VWDMRSGQCVQAFETHESDVNSVRYYPSGDAFASGSDDATCRLYDLRADREVAIYSKESI 324
           +WD+++G+C++    H   V +V +   G    S S D  CR++D  + + +     +  
Sbjct: 6   IWDVKTGKCLKTLPAHSDPVTAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLXTLIDDDN 185

Query: 325 IFGASSVDFSLSGRLLFAGYNDYTINVWDVLKGSRVSILFGHENRVSTLRVS---PDGTA 381
               S V FS +G+ + A   D T+ +WD  KG  +    GH N    +  +     G  
Sbjct: 186 P-PVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYVGHRNEKYCIFANFSVTGGKW 362

Query: 382 FCSGSWDHTLRVW 394
             SGS D+ + +W
Sbjct: 363 IVSGSEDNMVYIW 401

 Score = 48.5 bits (114), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 30/126 (23%), Positives = 59/126 (46%), Gaps = 4/126 (3%)
 Frame = +3

Query: 189 KSVAMHTNYLSACSFTNSDMQILTASGDGTCALWDVESGQLLQSF-HGHGADVLCLDLAP 247
           K++  H++ ++A  F      I+++S DG C +WD  SGQ L +        V  +  +P
Sbjct: 36  KTLPAHSDPVTAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLXTLIDDDNPPVSFVKFSP 215

Query: 248 SETGNTFVSGGCDKKAMVWDMRSGQCVQAFETHESD---VNSVRYYPSGDAFASGSDDAT 304
           +  G   ++   D    +WD   G+C++ +  H ++   + +      G    SGS+D  
Sbjct: 216 N--GKYILAATLDNTLKLWDYSKGKCLKTYVGHRNEKYCIFANFSVTGGKWIVSGSEDNM 389

Query: 305 CRLYDL 310
             +++L
Sbjct: 390 VYIWNL 407

 Score = 44.7 bits (104), Expect = 7e-05,   Method: Compositional matrix adjust.
 Identities = 47/188 (25%), Positives = 71/188 (37%), Gaps = 2/188 (1%)
 Frame = +3

Query: 96  KTRRTLKGHGNKVLCMDWCKDKRRIVSSSQDGKVIVWDSFTTNKEHAVTMPCTWVMACAY 155
           K  +TL  H + V  + + +D   IVSSS DG   +WD+                     
Sbjct: 27  KCLKTLPAHSDPVTAVHFNRDGSLIVSSSYDGLCRIWDT--------------------- 143

Query: 156 APSGCAIACGGLDNKCSVYPLTFDKNENMAAKKKSVAMHTNYLSACSFTNSDMQILTASG 215
           A   C       DN     P++F K                      F+ +   IL A+ 
Sbjct: 144 ASGQCLXTLIDDDNP----PVSFVK----------------------FSPNGKYILAATL 245

Query: 216 DGTCALWDVESGQLLQSFHGHGADVLCLDLAPSETGNTF-VSGGCDKKAMVWD-MRSGQC 273
           D T  LWD   G+ L+++ GH  +  C+    S TG  + VSG  D    +W+ +  G  
Sbjct: 246 DNTLKLWDYSKGKCLKTYVGHRNEKYCIFANFSVTGGKWIVSGSEDNMVYIWNLLDQGDS 425

Query: 274 VQAFETHE 281
            +A  +H 
Sbjct: 426 TEATGSHR 449
>02960
          Length = 1577

 Score = 56.6 bits (135), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 68/297 (22%), Positives = 123/297 (41%), Gaps = 41/297 (13%)
 Frame = +2

Query: 91  GQFVMKTRRTLKGHGNKVLCMDWCKDKRR-----IVSSSQDGKVIVWDSFTTNKE----- 140
           G+ +M    T+ GH + V C+ W K          V+ S D   +VW       E     
Sbjct: 572 GEAIM----TIPGHTSPVKCVAWIKHDESSGVSTFVTGSHDQTALVWQWQRETNEVDCRL 739

Query: 141 ----HAVTMPCTWVMACAYAPSGCAIACGGLDNKCSVYP----LTFDKNENMAAKKK--- 189
               HA ++ C      A +P    +  G  D    ++     +  D++E+     K   
Sbjct: 740 SCRGHAASVDC-----VAVSPDSQQMCTGSWDKMLKLWSTDCNVDGDQSEDTERPSKKKK 904

Query: 190 -------------SVAMHTNYLSACSFTNSDMQILTASGDGTCALWDVESGQLLQSFHGH 236
                        +++ H   +SA  + +   +++T+S D +  LWD+ + Q      G 
Sbjct: 905 SAKSTTQTRVPVLTLSGHAEAVSAVRWLDP-HRVVTSSWDHSLRLWDLHTAQQTSLIQGS 1081

Query: 237 GADVLCLDLAPSETGNTFVSGGCDKKAMVWDMR--SGQCVQ-AFETHESDVNSVRYYPSG 293
            A    LD+A S   +  ++G  D+   + D R   G+ V+ AF +H   V  V + P+ 
Sbjct: 1082KA---VLDVAYSPLSHMLITGSADRHVRLVDPRCSEGETVKCAFTSHTGWVTGVDWSPTR 1252

Query: 294 D-AFASGSDDATCRLYDLRADREVAI---YSKESIIFGASSVDFSLSGRLLFAGYND 346
           +  F SGS D   +L+D R+ +       + ++ I+    +VD+S+   LL  G ++
Sbjct: 1253EHLFLSGSYDNVLKLWDTRSPKATLYDMNWHEDRIL----AVDWSIPELLLSGGVDN 1411

 Score = 44.3 bits (103), Expect = 8e-05,   Method: Compositional matrix adjust.
 Identities = 47/191 (24%), Positives = 77/191 (40%), Gaps = 7/191 (3%)
 Frame = +2

Query: 211 LTASGDGTCALWDVESGQLLQSFHGHGADVLCLDLAPSETGN---TFVSGGCDKKAMVW- 266
           L+ S D T  LW  + G+ + +  GH + V C+     +  +   TFV+G  D+ A+VW 
Sbjct: 527 LSGSYDNTVRLWSTK-GEAIMTIPGHTSPVKCVAWIKHDESSGVSTFVTGSHDQTALVWQ 703

Query: 267 ---DMRSGQCVQAFETHESDVNSVRYYPSGDAFASGSDDATCRLYDLRADREVAIYSKES 323
              +     C  +   H + V+ V   P      +GS            D+ + ++S + 
Sbjct: 704 WQRETNEVDCRLSCRGHAASVDCVAVSPDSQQMCTGS-----------WDKMLKLWSTDC 850

Query: 324 IIFGASSVDFSLSGRLLFAGYNDYTINVWDVLKGSRVSILFGHENRVSTLRVSPDGTAFC 383
            + G  S D     +   +  +     V        V  L GH   VS +R   D     
Sbjct: 851 NVDGDQSEDTERPSKKKKSAKSTTQTRV-------PVLTLSGHAEAVSAVRWL-DPHRVV 1006

Query: 384 SGSWDHTLRVW 394
           + SWDH+LR+W
Sbjct: 1007TSSWDHSLRLW 1039

 Score = 40.8 bits (94), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 32/105 (30%), Positives = 48/105 (45%), Gaps = 7/105 (6%)
 Frame = +2

Query: 298 SGSDDATCRLYDLRADREVAIYSKESIIFGASSV--DFSLSGRLLFAGYNDYTINVWDVL 355
           SGS D T RL+  + +  + I    S +   + +  D S        G +D T  VW   
Sbjct: 530 SGSYDNTVRLWSTKGEAIMTIPGHTSPVKCVAWIKHDESSGVSTFVTGSHDQTALVWQWQ 709

Query: 356 KGS-----RVSILFGHENRVSTLRVSPDGTAFCSGSWDHTLRVWA 395
           + +     R+S   GH   V  + VSPD    C+GSWD  L++W+
Sbjct: 710 RETNEVDCRLSC-RGHAASVDCVAVSPDSQQMCTGSWDKMLKLWS 841

 Score = 31.2 bits (69), Expect = 0.80,   Method: Compositional matrix adjust.
 Identities = 49/218 (22%), Positives = 82/218 (37%), Gaps = 34/218 (15%)
 Frame = +2

Query: 211 LTASGDGTCALWDV--ESGQL--LQSFHGHGADVLCLDLAPSETGNTFVSGGCDKKAMVW 266
           +T S D T  +W    E+ ++    S  GH A V C+ ++P        +G  DK   +W
Sbjct: 665 VTGSHDQTALVWQWQRETNEVDCRLSCRGHAASVDCVAVSPD--SQQMCTGSWDKMLKLW 838

Query: 267 DM--------------------------RSGQCVQAFETHESDVNSVRYYPSGDAFASGS 300
                                       ++   V     H   V++VR+        S S
Sbjct: 839 STDCNVDGDQSEDTERPSKKKKSAKSTTQTRVPVLTLSGHAEAVSAVRWLDPHRVVTS-S 1015

Query: 301 DDATCRLYDLRADREVAIYSKESIIFGASSVDFSLSGRLLFAGYNDYTINVWDVL--KGS 358
            D + RL+DL   ++ ++      +     V +S    +L  G  D  + + D    +G 
Sbjct: 1016WDHSLRLWDLHTAQQTSLIQGSKAVL---DVAYSPLSHMLITGSADRHVRLVDPRCSEGE 1186

Query: 359 RVSILF-GHENRVSTLRVSPDGT-AFCSGSWDHTLRVW 394
            V   F  H   V+ +  SP     F SGS+D+ L++W
Sbjct: 1187TVKCAFTSHTGWVTGVDWSPTREHLFLSGSYDNVLKLW 1300
>10162
          Length = 1629

 Score = 53.1 bits (126), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 48/165 (29%), Positives = 77/165 (46%), Gaps = 11/165 (6%)
 Frame = +3

Query: 240 VLCLDLAPSETGNTFVSGGC-DKKAMVWDMRSGQCVQAF--------ETHESDVNSVRYY 290
           +LC+D +     N  +  GC D  A V+++ SG+   AF        +  ++ V SV + 
Sbjct: 378 ILCVDCSAD---NALIMSGCADATAKVFNVSSGKLXSAFNCAASQDSQDKDNSVESVAFC 548

Query: 291 PSGDAFASGSDDATCRLYDLRADREVAIYSKESIIFGASSVDFSLSGRLLFAGYNDYTIN 350
           P     A+ ++  + +++DL     VA +S +    G   + +S S  LL+    D  + 
Sbjct: 549 PVSPYAATATNSGSVQVWDLPT--SVARHSFQHP-EGVCKLQWSSSTALLYTACLDGVMR 719

Query: 351 VWDVLKGSRVSILFGHENRVSTL--RVSPDGTAFCSGSWDHTLRV 393
           VWD   G+  ++L GH      L   V+ DGT   SGS D T RV
Sbjct: 720 VWDARSGASKAVLTGHARNSCILDFDVTRDGTCLVSGSEDGTARV 854

 Score = 31.6 bits (70), Expect = 0.64,   Method: Compositional matrix adjust.
 Identities = 21/72 (29%), Positives = 29/72 (40%)
 Frame = +3

Query: 194 HTNYLSACSFTNSDMQILTASGDGTCALWDVESGQLLQSFHGHGADVLCLDLAPSETGNT 253
           H   +    +++S   + TA  DG   +WD  SG       GH  +   LD   +  G  
Sbjct: 639 HPEGVCKLQWSSSTALLYTACLDGVMRVWDARSGASKAVLTGHARNSCILDFDVTRDGTC 818

Query: 254 FVSGGCDKKAMV 265
            VSG  D  A V
Sbjct: 819 LVSGSEDGTARV 854
>12574
          Length = 521

 Score = 48.9 bits (115), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 34/119 (28%), Positives = 58/119 (48%), Gaps = 3/119 (2%)
 Frame = +3

Query: 280 HESDVNSVRYYPSGDAFASGSDDATCRL---YDLRADREVAIYSKESIIFGASSVDFSLS 336
           H   +++V++ P+GD  AS S D   ++   YD + ++ +A +       G S V +S  
Sbjct: 183 HTKALSAVKFSPNGDWLASSSADKLIKIWGAYDGKFEKTIAGHK-----LGLSDVAWSSD 347

Query: 337 GRLLFAGYNDYTINVWDVLKGSRVSILFGHENRVSTLRVSPDGTAFCSGSWDHTLRVWA 395
            +LL +  +D T+ +W+   G  +  L GH N V     +P      SGS    +RV+A
Sbjct: 348 SKLLCSASDDKTLKIWEFSTGKCMKTLKGHSNYVFCCNFNPQSNLIVSGS---LMRVFA 515

 Score = 46.6 bits (109), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 29/113 (25%), Positives = 52/113 (46%)
 Frame = +3

Query: 188 KKSVAMHTNYLSACSFTNSDMQILTASGDGTCALWDVESGQLLQSFHGHGADVLCLDLAP 247
           K ++A HT  LSA  F+ +   + ++S D    +W    G+  ++  GH   +   D+A 
Sbjct: 165 KFTLAGHTKALSAVKFSPNGDWLASSSADKLIKIWGAYDGKFEKTIAGHKLGLS--DVAW 338

Query: 248 SETGNTFVSGGCDKKAMVWDMRSGQCVQAFETHESDVNSVRYYPSGDAFASGS 300
           S       S   DK   +W+  +G+C++  + H + V    + P  +   SGS
Sbjct: 339 SSDSKLLCSASDDKTLKIWEFSTGKCMKTLKGHSNYVFCCNFNPQSNLIVSGS 497

 Score = 38.1 bits (87), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 27/106 (25%), Positives = 49/106 (46%)
 Frame = +3

Query: 152 ACAYAPSGCAIACGGLDNKCSVYPLTFDKNENMAAKKKSVAMHTNYLSACSFTNSDMQIL 211
           A  ++P+G  +A    D    ++     K E      K++A H   LS  ++++    + 
Sbjct: 201 AVKFSPNGDWLASSSADKLIKIWGAYDGKFE------KTIAGHKLGLSDVAWSSDSKLLC 362

Query: 212 TASGDGTCALWDVESGQLLQSFHGHGADVLCLDLAPSETGNTFVSG 257
           +AS D T  +W+  +G+ +++  GH   V C +  P    N  VSG
Sbjct: 363 SASDDKTLKIWEFSTGKCMKTLKGHSNYVFCCNFNPQS--NLIVSG 494

 Score = 30.8 bits (68), Expect = 1.0,   Method: Compositional matrix adjust.
 Identities = 20/82 (24%), Positives = 37/82 (45%), Gaps = 1/82 (1%)
 Frame = +3

Query: 87  VEALGQFVMKTRRTLKGHGNKVLCMDWCKDKRRIVSSSQDGKVIVWDSFTTNK-EHAVTM 145
           ++  G +  K  +T+ GH   +  + W  D + + S+S D  + +W+ F+T K    +  
Sbjct: 258 IKIWGAYDGKFEKTIAGHKLGLSDVAWSSDSKLLCSASDDKTLKIWE-FSTGKCMKTLKG 434

Query: 146 PCTWVMACAYAPSGCAIACGGL 167
              +V  C + P    I  G L
Sbjct: 435 HSNYVFCCNFNPQSNLIVSGSL 500

 Score = 29.3 bits (64), Expect = 3.2,   Method: Compositional matrix adjust.
 Identities = 16/80 (20%), Positives = 33/80 (41%)
 Frame = +3

Query: 235 GHGADVLCLDLAPSETGNTFVSGGCDKKAMVWDMRSGQCVQAFETHESDVNSVRYYPSGD 294
           GH   +  +  +P+  G+   S   DK   +W    G+  +    H+  ++ V +     
Sbjct: 180 GHTKALSAVKFSPN--GDWLASSSADKLIKIWGAYDGKFEKTIAGHKLGLSDVAWSSDSK 353

Query: 295 AFASGSDDATCRLYDLRADR 314
              S SDD T ++++    +
Sbjct: 354 LLCSASDDKTLKIWEFSTGK 413

 Score = 28.5 bits (62), Expect = 5.5,   Method: Compositional matrix adjust.
 Identities = 11/32 (34%), Positives = 18/32 (56%)
 Frame = +3

Query: 363 LFGHENRVSTLRVSPDGTAFCSGSWDHTLRVW 394
           L GH   +S ++ SP+G    S S D  +++W
Sbjct: 174 LAGHTKALSAVKFSPNGDWLASSSADKLIKIW 269
>18981
          Length = 407

 Score = 48.5 bits (114), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 33/104 (31%), Positives = 53/104 (50%)
 Frame = -2

Query: 207 DMQILTASGDGTCALWDVESGQLLQSFHGHGADVLCLDLAPSETGNTFVSGGCDKKAMVW 266
           D  I++A+ D T  +W +++  LL +  GH  DV C+ +     G   VSG  DK  +VW
Sbjct: 388 DNMIISAATDRTLRVWCLKNTCLLHTLRGHNDDVECVCIY----GRRVVSGSWDKTLIVW 221

Query: 267 DMRSGQCVQAFETHESDVNSVRYYPSGDAFASGSDDATCRLYDL 310
           ++ +G+ V     H   + +V+ +  G A  SGS D   R + L
Sbjct: 220 EVDTGRPVHQLHGHTEAITAVQ-FDEGKA-VSGSADGDVRTWAL 95

 Score = 38.1 bits (87), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 18/71 (25%), Positives = 34/71 (47%)
 Frame = -2

Query: 209 QILTASGDGTCALWDVESGQLLQSFHGHGADVLCLDLAPSETGNTFVSGGCDKKAMVWDM 268
           ++++ S D T  +W+V++G+ +   HGH   +  +     +     VSG  D     W +
Sbjct: 262 RVVSGSWDKTLIVWEVDTGRPVHQLHGHTEAITAVQFDEGKA----VSGSADGDVRTWAL 95

Query: 269 RSGQCVQAFET 279
            +GQC+    T
Sbjct: 94  DTGQCLLTMTT 62

 Score = 33.5 bits (75), Expect = 0.17,   Method: Compositional matrix adjust.
 Identities = 18/45 (40%), Positives = 25/45 (55%)
 Frame = -2

Query: 99  RTLKGHGNKVLCMDWCKDKRRIVSSSQDGKVIVWDSFTTNKEHAV 143
            TL+GH + V C+  C   RR+VS S D  +IVW+  T    H +
Sbjct: 316 HTLRGHNDDVECV--CIYGRRVVSGSWDKTLIVWEVDTGRPVHQL 188

 Score = 33.1 bits (74), Expect = 0.18,   Method: Compositional matrix adjust.
 Identities = 22/61 (36%), Positives = 33/61 (54%)
 Frame = -2

Query: 335 LSGRLLFAGYNDYTINVWDVLKGSRVSILFGHENRVSTLRVSPDGTAFCSGSWDHTLRVW 394
           + GR + +G  D T+ VW+V  G  V  L GH   ++ ++   +G A  SGS D  +R W
Sbjct: 274 IYGRRVVSGSWDKTLIVWEVDTGRPVHQLHGHTEAITAVQFD-EGKAV-SGSADGDVRTW 101

Query: 395 A 395
           A
Sbjct: 100 A 98
>01768
          Length = 1424

 Score = 46.2 bits (108), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 33/131 (25%), Positives = 54/131 (41%), Gaps = 9/131 (6%)
 Frame = +3

Query: 232 SFHGHGADVLCLDLAPSETGNTFVSGGCDKKAMVWDMRS----GQCVQAFETHESDVNSV 287
           S+  H   V  +  +P+E GN F S   D+   +W+ +        +   E H  D+N +
Sbjct: 822 SYAAHTDSVEDVQWSPNE-GNVFASCSVDRTLRIWNTQQKPSKANVLTVPEAHSRDINVI 998

Query: 288 RYYP-SGDAFASGSDDATCRLYDLRADREVAIYSKESIIFGASSVDF----SLSGRLLFA 342
            + P      ASG DD   +++DLR  R   + ++ S    +  V           +L A
Sbjct: 999 NWNPIEKHLLASGGDDGIIKIWDLRMFRNKPVSAQASFKLHSQPVTSLEWNPQDSSVLAA 1178

Query: 343 GYNDYTINVWD 353
              D  I +WD
Sbjct: 1179SGEDDQITIWD 1211
>03395
          Length = 2795

 Score = 46.2 bits (108), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 30/128 (23%), Positives = 51/128 (39%), Gaps = 2/128 (1%)
 Frame = +2

Query: 183 NMAAKKKSVAMHTNYLSACS-FTNSDMQILTASGDGTCALWDVESGQLLQSFHGHGADVL 241
           ++    +S  +  N L  C  F   D+ ILT+  D     W+V  G LL+   G     +
Sbjct: 230 DLITNTRSQIVLANTLFKCVCFGGKDLHILTSGTDHKIGYWEVGDGGLLRELEGSQTGAI 409

Query: 242 -CLDLAPSETGNTFVSGGCDKKAMVWDMRSGQCVQAFETHESDVNSVRYYPSGDAFASGS 300
             +D+     G T ++GG D    +W    G+       H + +   R  P+     SG 
Sbjct: 410 NTIDI--DRDGQTILTGGEDSLLKLWRYNEGEVTHTGIGHSNQITKARICPNRHYIVSGG 583

Query: 301 DDATCRLY 308
           +D    ++
Sbjct: 584 EDGALHIW 607

 Score = 45.1 bits (105), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 37/198 (18%), Positives = 69/198 (34%), Gaps = 48/198 (24%)
 Frame = +2

Query: 245 LAPSETGNTFVSGGCDKKAMVWDM--------RSGQCVQAFETHESDVNSVRYYPSGDAF 296
           +A +  G   VSGG + +  VWD+          G  V   + H+  V +++ + +    
Sbjct: 14  IAVTSCGTKLVSGGGEGQVRVWDIVKDMLTGKTRGDLVANMKEHKGKVTAIQIHTNDRCC 193

Query: 297 ASGSDDATCRLYDLRADREVAIYSKESII----FGA------------------------ 328
            S S D +  ++DL  +    I    ++     FG                         
Sbjct: 194 VSASTDGSTIIWDLITNTRSQIVLANTLFKCVCFGGKDLHILTSGTDHKIGYWEVGDGGL 373

Query: 329 ------------SSVDFSLSGRLLFAGYNDYTINVWDVLKGSRVSILFGHENRVSTLRVS 376
                       +++D    G+ +  G  D  + +W   +G       GH N+++  R+ 
Sbjct: 374 LRELEGSQTGAINTIDIDRDGQTILTGGEDSLLKLWRYNEGEVTHTGIGHSNQITKARIC 553

Query: 377 PDGTAFCSGSWDHTLRVW 394
           P+     SG  D  L +W
Sbjct: 554 PNRHYIVSGGEDGALHIW 607
>11493
          Length = 535

 Score = 45.8 bits (107), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 41/163 (25%), Positives = 70/163 (42%), Gaps = 6/163 (3%)
 Frame = -2

Query: 236 HGADVLCLDLAPSETGNTFVSG-GCDKKAMVWDMR---SGQCVQAFETHESD--VNSVRY 289
           HG +V+C     + T   +  G GC K   VWD+    +   V   +  + D  + SV+ 
Sbjct: 480 HG-EVVCAVTISNPTKYVYTGGKGCVK---VWDISQPGNKNPVSQLDCLQRDNYIRSVKL 313

Query: 290 YPSGDAFASGSDDATCRLYDLRADREVAIYSKESIIFGASSVDFSLSGRLLFAGYNDYTI 349
            P G     G + +   ++DL +          S      ++  S   ++ F+  +D  I
Sbjct: 312 LPDGRTLIVGGEASNLSIWDLASPTPRIKAELTSAAPACYALAISPDSKVCFSCCSDGNI 133

Query: 350 NVWDVLKGSRVSILFGHENRVSTLRVSPDGTAFCSGSWDHTLR 392
            VWD+     V    GH +  S + +SPDG+   +G  D+T+R
Sbjct: 132 AVWDLHNEILVRQFQGHTDGASCIDISPDGSRLWTGGLDNTVR 4

 Score = 42.4 bits (98), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 42/167 (25%), Positives = 69/167 (41%), Gaps = 9/167 (5%)
 Frame = -2

Query: 104 HGNKVLCMDWCKDKRRIVSSSQDGKVIVWD-SFTTNKEHAVTMPC----TWVMACAYAPS 158
           HG +V+C     +  + V +   G V VWD S   NK     + C     ++ +    P 
Sbjct: 480 HG-EVVCAVTISNPTKYVYTGGKGCVKVWDISQPGNKNPVSQLDCLQRDNYIRSVKLLPD 304

Query: 159 GCAIACGGLDNKCSVY----PLTFDKNENMAAKKKSVAMHTNYLSACSFTNSDMQILTAS 214
           G  +  GG  +  S++    P    K E  +A     A+  +  S   F+          
Sbjct: 303 GRTLIVGGEASNLSIWDLASPTPRIKAELTSAAPACYALAISPDSKVCFS--------CC 148

Query: 215 GDGTCALWDVESGQLLQSFHGHGADVLCLDLAPSETGNTFVSGGCDK 261
            DG  A+WD+ +  L++ F GH     C+D++P   G+   +GG D 
Sbjct: 147 SDGNIAVWDLHNEILVRQFQGHTDGASCIDISPD--GSRLWTGGLDN 13
>34511
          Length = 1037

 Score = 45.4 bits (106), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 21/39 (53%), Positives = 26/39 (66%)
 Frame = +3

Query: 356 KGSRVSILFGHENRVSTLRVSPDGTAFCSGSWDHTLRVW 394
           K  R  IL GH+NRVS L V+ +G +  +GSWD  LRVW
Sbjct: 39  KAERSGILAGHDNRVSCLGVTENGMSVATGSWDSFLRVW 155
>01462
          Length = 995

 Score = 44.7 bits (104), Expect = 6e-05,   Method: Compositional matrix adjust.
 Identities = 20/62 (32%), Positives = 33/62 (53%)
 Frame = +2

Query: 254 FVSGGCDKKAMVWDMRSGQCVQAFETHESDVNSVRYYPSGDAFASGSDDATCRLYDLRAD 313
             +G  D+K  VWD+ +GQ + A E H+  ++ V          S S+D T R++D+R+ 
Sbjct: 242 LYAGAGDRKIHVWDIEAGQYLNAMEGHKDYIHKVVMKNDAQECVSASEDGTVRMWDIRSS 421

Query: 314 RE 315
            E
Sbjct: 422 TE 427

 Score = 43.1 bits (100), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 21/65 (32%), Positives = 36/65 (55%)
 Frame = +2

Query: 330 SVDFSLSGRLLFAGYNDYTINVWDVLKGSRVSILFGHENRVSTLRVSPDGTAFCSGSWDH 389
           +VD  +  R L+AG  D  I+VWD+  G  ++ + GH++ +  + +  D     S S D 
Sbjct: 212 AVDEKMGTRRLYAGAGDRKIHVWDIEAGQYLNAMEGHKDYIHKVVMKNDAQECVSASEDG 391

Query: 390 TLRVW 394
           T+R+W
Sbjct: 392 TVRMW 406

 Score = 32.0 bits (71), Expect = 0.43,   Method: Compositional matrix adjust.
 Identities = 19/77 (24%), Positives = 36/77 (46%), Gaps = 1/77 (1%)
 Frame = +2

Query: 209 QILTASGDGTCALWDVESGQLLQSFHGHGADVLCLDLAPSETGNTFVSGGCDKKAMVWDM 268
           ++   +GD    +WD+E+GQ L +  GH   +  + +         VS   D    +WD+
Sbjct: 239 RLYAGAGDRKIHVWDIEAGQYLNAMEGHKDYIHKVVM--KNDAQECVSASEDGTVRMWDI 412

Query: 269 RSG-QCVQAFETHESDV 284
           RS  + V   E  ++++
Sbjct: 413 RSSTETVHCLEPSKNEL 463

 Score = 31.2 bits (69), Expect = 0.81,   Method: Compositional matrix adjust.
 Identities = 28/108 (25%), Positives = 41/108 (37%), Gaps = 11/108 (10%)
 Frame = +2

Query: 194 HTNYLSACSFTNSDMQILTASGDGTCALWDVESG-----------QLLQSFHGHGADVLC 242
           H +Y+      N   + ++AS DGT  +WD+ S              L S    G  + C
Sbjct: 320 HKDYIHKVVMKNDAQECVSASEDGTVRMWDIRSSTETVHCLEPSKNELCSRPLLGKWLRC 499

Query: 243 LDLAPSETGNTFVSGGCDKKAMVWDMRSGQCVQAFETHESDVNSVRYY 290
           L L P E     V GG   K   W +R+      F+T     N   ++
Sbjct: 500 LALDPEE--GWLVCGG-GPKLSAWHLRTLAPTTIFDTPSVSQNVALFH 634
>15780
          Length = 735

 Score = 44.3 bits (103), Expect = 8e-05,   Method: Compositional matrix adjust.
 Identities = 20/49 (40%), Positives = 30/49 (61%)
 Frame = -1

Query: 346 DYTINVWDVLKGSRVSILFGHENRVSTLRVSPDGTAFCSGSWDHTLRVW 394
           D+T+ VWD+  G+ V+ L  H + V  L  S DGT   SG  D+++R+W
Sbjct: 711 DHTVIVWDIASGTAVAHLTAHTDTVYALCFSRDGTVLASGGMDNSIRLW 565

 Score = 39.3 bits (90), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 19/55 (34%), Positives = 27/55 (49%)
 Frame = -1

Query: 256 SGGCDKKAMVWDMRSGQCVQAFETHESDVNSVRYYPSGDAFASGSDDATCRLYDL 310
           + G D   +VWD+ SG  V     H   V ++ +   G   ASG  D + RL+DL
Sbjct: 723 TAGADHTVIVWDIASGTAVAHLTAHTDTVYALCFSRDGTVLASGGMDNSIRLWDL 559

 Score = 35.0 bits (79), Expect = 0.048,   Method: Compositional matrix adjust.
 Identities = 26/77 (33%), Positives = 33/77 (42%), Gaps = 2/77 (2%)
 Frame = -1

Query: 212 TASGDGTCALWDVESGQLLQSFHGHGADV--LCLDLAPSETGNTFVSGGCDKKAMVWDMR 269
           TA  D T  +WD+ SG  +     H   V  LC     S  G    SGG D    +WD+ 
Sbjct: 723 TAGADHTVIVWDIASGTAVAHLTAHTDTVYALCF----SRDGTVLASGGMDNSIRLWDLA 556

Query: 270 SGQCVQAFETHESDVNS 286
                Q  ET +S+V S
Sbjct: 555 RVMEEQDPET-DSNVPS 508

 Score = 28.9 bits (63), Expect = 3.6,   Method: Compositional matrix adjust.
 Identities = 16/59 (27%), Positives = 28/59 (47%)
 Frame = -1

Query: 118 RRIVSSSQDGKVIVWDSFTTNKEHAVTMPCTWVMACAYAPSGCAIACGGLDNKCSVYPL 176
           + + ++  D  VIVWD  +      +T     V A  ++  G  +A GG+DN   ++ L
Sbjct: 735 KYLSTAGADHTVIVWDIASGTAVAHLTAHTDTVYALCFSRDGTVLASGGMDNSIRLWDL 559
>13278
          Length = 870

 Score = 44.3 bits (103), Expect = 8e-05,   Method: Compositional matrix adjust.
 Identities = 26/105 (24%), Positives = 51/105 (48%), Gaps = 9/105 (8%)
 Frame = +1

Query: 265 VWDMRSGQCVQAFETHESDVNSVRYYPSGDA---------FASGSDDATCRLYDLRADRE 315
           +W M    C+   +    ++ ++++ P+G            AS S D+T RL+++  +R 
Sbjct: 1   IWSMGKDSCIHDLQLTTKEIYTIKWSPTGPGTSNPNTSLILASASFDSTVRLWEV--ERG 174

Query: 316 VAIYSKESIIFGASSVDFSLSGRLLFAGYNDYTINVWDVLKGSRV 360
           + +++         SV FS  G+ L +G  D  +++W+V  GS V
Sbjct: 175 LCLHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNVQTGSLV 309

 Score = 40.4 bits (93), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 23/113 (20%), Positives = 43/113 (38%), Gaps = 7/113 (6%)
 Frame = +1

Query: 221 LWDVESGQLLQSFHGHGADVLCLDLAPSETGNT-------FVSGGCDKKAMVWDMRSGQC 273
           +W +     +        ++  +  +P+  G +         S   D    +W++  G C
Sbjct: 1   IWSMGKDSCIHDLQLTTKEIYTIKWSPTGPGTSNPNTSLILASASFDSTVRLWEVERGLC 180

Query: 274 VQAFETHESDVNSVRYYPSGDAFASGSDDATCRLYDLRADREVAIYSKESIIF 326
           +     H+  V SV + P G   ASGS D    +++++    V  Y     IF
Sbjct: 181 LHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNVQTGSLVHSYKGTGGIF 339
>37180
          Length = 681

 Score = 43.1 bits (100), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 28/79 (35%), Positives = 36/79 (45%), Gaps = 1/79 (1%)
 Frame = +1

Query: 237 GADVLCLDLAPSETGNTFVSGGCDKKAMVWDMR-SGQCVQAFETHESDVNSVRYYPSGDA 295
           G D    D+    T    V+   D    +WD R S   V  F+ H   V S   + SGD 
Sbjct: 13  GHDQELSDVHAHPTQRLVVTSSKDMTFRLWDFRDSALLVNVFQGHTQPVTSA-VFASGDK 189

Query: 296 FASGSDDATCRLYDLRADR 314
             SGSDD T R++D+R  R
Sbjct: 190 VVSGSDDRTVRVWDMRNMR 246

 Score = 42.7 bits (99), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 33/103 (32%), Positives = 47/103 (45%), Gaps = 4/103 (3%)
 Frame = +1

Query: 194 HTNYLSACSFTNSDMQILTASGDGTCALWDV-ESGQLLQSFHGHGADVLCLDLAPSETGN 252
           H   LS      +   ++T+S D T  LWD  +S  L+  F GH   V     A   +G+
Sbjct: 16  HDQELSDVHAHPTQRLVVTSSKDMTFRLWDFRDSALLVNVFQGHTQPVTSAVFA---SGD 186

Query: 253 TFVSGGCDKKAMVWDMRSGQCVQAFETHESDVNS---VRYYPS 292
             VSG  D+   VWDMR+ +   A    +S VN     +Y P+
Sbjct: 187 KVVSGSDDRTVRVWDMRNMRSPIATIRTDSAVNRFV*FQYRPA 315

 Score = 30.4 bits (67), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 20/58 (34%), Positives = 28/58 (48%), Gaps = 1/58 (1%)
 Frame = +1

Query: 338 RLLFAGYNDYTINVWDVLKGSR-VSILFGHENRVSTLRVSPDGTAFCSGSWDHTLRVW 394
           RL+     D T  +WD    +  V++  GH   V++  V   G    SGS D T+RVW
Sbjct: 58  RLVVTSSKDMTFRLWDFRDSALLVNVFQGHTQPVTSA-VFASGDKVVSGSDDRTVRVW 228
>21105
          Length = 650

 Score = 42.7 bits (99), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 26/102 (25%), Positives = 47/102 (46%), Gaps = 4/102 (3%)
 Frame = +1

Query: 211 LTASGDGTCALWDVESGQLLQSFHGHGADVLCLDLAPSETGNTFVSGGCDKKAMVWDMRS 270
           +TA  D     +D  +G+L+ +   H   V  L + P+  G   +SG  D    +W++ S
Sbjct: 112 ITAHEDRHIRFFDNNTGKLIHAMVAHLDSVTSLAVDPN--GLYLLSGSHDCSIRLWNLDS 285

Query: 271 GQCVQAFETH----ESDVNSVRYYPSGDAFASGSDDATCRLY 308
             CVQ   +H    +  ++ V ++P     AS   DA  +++
Sbjct: 286 KTCVQEITSHRKKFDESIHDVAFHPQKPYIASAGADALAKVF 411

 Score = 35.0 bits (79), Expect = 0.058,   Method: Compositional matrix adjust.
 Identities = 16/56 (28%), Positives = 28/56 (50%)
 Frame = +1

Query: 339 LLFAGYNDYTINVWDVLKGSRVSILFGHENRVSTLRVSPDGTAFCSGSWDHTLRVW 394
           +    + D  I  +D   G  +  +  H + V++L V P+G    SGS D ++R+W
Sbjct: 106 ITITAHEDRHIRFFDNNTGKLIHAMVAHLDSVTSLAVDPNGLYLLSGSHDCSIRLW 273

 Score = 33.1 bits (74), Expect = 0.21,   Method: Compositional matrix adjust.
 Identities = 16/56 (28%), Positives = 28/56 (50%)
 Frame = +1

Query: 255 VSGGCDKKAMVWDMRSGQCVQAFETHESDVNSVRYYPSGDAFASGSDDATCRLYDL 310
           ++   D+    +D  +G+ + A   H   V S+   P+G    SGS D + RL++L
Sbjct: 112 ITAHEDRHIRFFDNNTGKLIHAMVAHLDSVTSLAVDPNGLYLLSGSHDCSIRLWNL 279
>01249
          Length = 1743

 Score = 42.7 bits (99), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 16/36 (44%), Positives = 25/36 (69%)
 Frame = -1

Query: 98  RRTLKGHGNKVLCMDWCKDKRRIVSSSQDGKVIVWD 133
            R L+GH + V C+ +  D +R+ S SQ+GKVI+W+
Sbjct: 936 ERVLQGHSDAVTCLAFSSDGQRLASGSQNGKVIIWN 829

 Score = 34.7 bits (78), Expect = 0.066,   Method: Compositional matrix adjust.
 Identities = 29/119 (24%), Positives = 51/119 (42%), Gaps = 15/119 (12%)
 Frame = -1

Query: 209  QILTASGDGTCALWDVESGQLLQSFHGHGADVLCLDLAPSETGNTFVSGGCDKKAMVWDM 268
            ++ ++S DGTC LWD+ SG LL++   +   V CL +   E    F+  G D   ++   
Sbjct: 1164 RVASSSSDGTCKLWDMLSGALLRTMV-YETGVGCLIMDKQE---HFLLAGLDNGDILCSP 997

Query: 269  RSGQCVQA---------------FETHESDVNSVRYYPSGDAFASGSDDATCRLYDLRA 312
              GQ  Q+                + H   V  + +   G   ASGS +    ++++ +
Sbjct: 996  LFGQISQSEVFVSKHTTKAGERVLQGHSDAVTCLAFSSDGQRLASGSQNGKVIIWNMES 820

 Score = 33.5 bits (75), Expect = 0.15,   Method: Compositional matrix adjust.
 Identities = 34/146 (23%), Positives = 59/146 (40%), Gaps = 13/146 (8%)
 Frame = -1

Query: 95   MKTRRTLKGHGNKV--LCMDWCKDKRRIVSSSQDGKVIVWDSFTTNKEHAVTMPCTWVMA 152
            +K  RT+  H   +  L +       R+ SSS DG   +WD  +       TM     + 
Sbjct: 1242 LKPGRTINAHSEPITGLHVGCGGPAARVASSSSDGTCKLWDMLSGALLR--TMVYETGVG 1069

Query: 153  CAYAPSGCAIACGGLDNK---CSVYPL--------TFDKNENMAAKKKSVAMHTNYLSAC 201
            C            GLDN    CS  PL         F       A ++ +  H++ ++  
Sbjct: 1068 CLIMDKQEHFLLAGLDNGDILCS--PLFGQISQSEVFVSKHTTKAGERVLQGHSDAVTCL 895

Query: 202  SFTNSDMQILTASGDGTCALWDVESG 227
            +F++   ++ + S +G   +W++ESG
Sbjct: 894  AFSSDGQRLASGSQNGKVIIWNMESG 817

 Score = 30.4 bits (67), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 38/177 (21%), Positives = 66/177 (37%), Gaps = 30/177 (16%)
 Frame = -1

Query: 248  SETGNTFVSGGCDKKAMVWD--------------MRSGQCVQAFETHESDVNSVRYYPSG 293
            ++ G+ FV         +WD              ++ G+ + A   H   +  +     G
Sbjct: 1344 TDDGSQFVVATSSGHLNIWDFARVVTTTSQRARGLKPGRTINA---HSEPITGLHVGCGG 1174

Query: 294  DA--FASGSDDATCRLYDLRADREVAIYSKESIIFGASSVDFSLSGRLLFAGYNDYTI-- 349
             A   AS S D TC+L+D+ +   +     E+   G   +        L AG ++  I  
Sbjct: 1173 PAARVASSSSDGTCKLWDMLSGALLRTMVYET---GVGCLIMDKQEHFLLAGLDNGDILC 1003

Query: 350  -NVWDVLKGSRV-----------SILFGHENRVSTLRVSPDGTAFCSGSWDHTLRVW 394
              ++  +  S V            +L GH + V+ L  S DG    SGS +  + +W
Sbjct: 1002 SPLFGQISQSEVFVSKHTTKAGERVLQGHSDAVTCLAFSSDGQRLASGSQNGKVIIW 832
>19498
          Length = 903

 Score = 42.4 bits (98), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 42/148 (28%), Positives = 63/148 (42%), Gaps = 1/148 (0%)
 Frame = -1

Query: 248 SETGNTFVSGGCDKKAMVWDMRSGQCVQAFETHESDVNSVRYYPSGDAFASGSDDATCRL 307
           SE G    SGG DK  M+W +  G    + ++  S+V  + ++ S       + D    +
Sbjct: 759 SENGKFLASGGDDKLIMIWQISRG--FGSGKSFGSNVTILEHWRSVATLRGHAGD----V 598

Query: 308 YDLRADREVAIYSKESIIFGASSVDFSLSGRLLFAGYNDYTINVWDVLKGS-RVSILFGH 366
            DL        +S + +   + SVD               TI VW+ LK S +V+++ GH
Sbjct: 597 LDL-------AWSPQDLWLASCSVD--------------NTIVVWNALKFSEQVAVIRGH 481

Query: 367 ENRVSTLRVSPDGTAFCSGSWDHTLRVW 394
              V  +   P G    S S D TLRVW
Sbjct: 480 AGMVKGVTWDPVGRYLASQSDDKTLRVW 397

 Score = 30.4 bits (67), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 14/44 (31%), Positives = 24/44 (54%)
 Frame = -1

Query: 100 TLKGHGNKVLCMDWCKDKRRIVSSSQDGKVIVWDSFTTNKEHAV 143
           TL+GH   VL + W      + S S D  ++VW++   +++ AV
Sbjct: 624 TLRGHAGDVLDLAWSPQDLWLASCSVDNTIVVWNALKFSEQVAV 493

 Score = 30.4 bits (67), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 23/81 (28%), Positives = 34/81 (41%), Gaps = 17/81 (20%)
 Frame = -1

Query: 331 VDFSLSGRLLFAGYNDYTINVWDVLKG-----------------SRVSILFGHENRVSTL 373
           V +S +G+ L +G +D  I +W + +G                   V+ L GH   V  L
Sbjct: 768 VRWSENGKFLASGGDDKLIMIWQISRGFGSGKSFGSNVTILEHWRSVATLRGHAGDVLDL 589

Query: 374 RVSPDGTAFCSGSWDHTLRVW 394
             SP      S S D+T+ VW
Sbjct: 588 AWSPQDLWLASCSVDNTIVVW 526
>35607
          Length = 475

 Score = 42.4 bits (98), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 26/110 (23%), Positives = 48/110 (43%)
 Frame = +2

Query: 251 GNTFVSGGCDKKAMVWDMRSGQCVQAFETHESDVNSVRYYPSGDAFASGSDDATCRLYDL 310
           G    +GG D     WD+R G+ +Q  +   S + S+ Y P+GD  A G + +   +   
Sbjct: 14  GTKLWTGGLDNTVRSWDLREGRQLQQHD-FSSQIFSLGYCPTGDWLAVGMESSNVEVLHH 190

Query: 311 RADREVAIYSKESIIFGASSVDFSLSGRLLFAGYNDYTINVWDVLKGSRV 360
               +  ++  ES +    S+ F+  G+   +   D  +N W    G+ +
Sbjct: 191 SKPDKYQLHLHESCVL---SLKFAYCGKWFVSTGKDNLLNAWRTPYGASI 331

 Score = 34.7 bits (78), Expect = 0.065,   Method: Compositional matrix adjust.
 Identities = 29/104 (27%), Positives = 45/104 (43%)
 Frame = +2

Query: 291 PSGDAFASGSDDATCRLYDLRADREVAIYSKESIIFGASSVDFSLSGRLLFAGYNDYTIN 350
           P G    +G  D T R +DLR  R++  +   S IF   S+ +  +G  L  G     + 
Sbjct: 8   PDGTKLWTGGLDNTVRSWDLREGRQLQQHDFSSQIF---SLGYCPTGDWLAVGMESSNVE 178

Query: 351 VWDVLKGSRVSILFGHENRVSTLRVSPDGTAFCSGSWDHTLRVW 394
           V    K  +  +   HE+ V +L+ +  G  F S   D+ L  W
Sbjct: 179 VLHHSKPDKYQLHL-HESCVLSLKFAYCGKWFVSTGKDNLLNAW 307
>31384
          Length = 474

 Score = 42.0 bits (97), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 26/77 (33%), Positives = 43/77 (55%), Gaps = 2/77 (2%)
 Frame = -1

Query: 210 ILTASGDGTCALWDVE-SGQLL-QSFHGHGADVLCLDLAPSETGNTFVSGGCDKKAMVWD 267
           +++ S D   + W+V+ SGQ + ++   H   VL +D   S+ G    +  CDK A VWD
Sbjct: 222 LISGSWDNKVSCWEVQQSGQTIPKAQQTHTGPVLDVDW--SDDGTKVFTASCDKTAKVWD 49

Query: 268 MRSGQCVQAFETHESDV 284
           + S QC+Q  + H++ V
Sbjct: 48  LNSNQCMQIAQ-HDAPV 1

 Score = 31.6 bits (70), Expect = 0.52,   Method: Compositional matrix adjust.
 Identities = 16/48 (33%), Positives = 25/48 (52%)
 Frame = -1

Query: 86  RVEALGQFVMKTRRTLKGHGNKVLCMDWCKDKRRIVSSSQDGKVIVWD 133
            V+  GQ + K ++T   H   VL +DW  D  ++ ++S D    VWD
Sbjct: 183 EVQQSGQTIPKAQQT---HTGPVLDVDWSDDGTKVFTASCDKTAKVWD 49

 Score = 30.4 bits (67), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 27/106 (25%), Positives = 47/106 (44%), Gaps = 4/106 (3%)
 Frame = -1

Query: 139 KEHAVTMPCTWVMAC-AYAPSGCA---IACGGLDNKCSVYPLTFDKNENMAAKKKSVAMH 194
           K+  VT P    ++C  ++P       +  G  DNK S +    +  ++     K+   H
Sbjct: 303 KDFEVTSPPDDSVSCLKFSPGALPSTFLISGSWDNKVSCW----EVQQSGQTIPKAQQTH 136

Query: 195 TNYLSACSFTNSDMQILTASGDGTCALWDVESGQLLQSFHGHGADV 240
           T  +    +++   ++ TAS D T  +WD+ S Q +Q    H A V
Sbjct: 135 TGPVLDVDWSDDGTKVFTASCDKTAKVWDLNSNQCMQ-IAQHDAPV 1
>14500
          Length = 1238

 Score = 41.2 bits (95), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 20/52 (38%), Positives = 28/52 (53%)
 Frame = +3

Query: 343 GYNDYTINVWDVLKGSRVSILFGHENRVSTLRVSPDGTAFCSGSWDHTLRVW 394
           G+    + +W     SRV+ L GH  RV  + +SPDG    S + D TLR+W
Sbjct: 393 GFAQNQLIIWKYPAMSRVAELTGHTARVLHMAMSPDGETVVSAAADETLRLW 548

 Score = 32.0 bits (71), Expect = 0.44,   Method: Compositional matrix adjust.
 Identities = 17/36 (47%), Positives = 19/36 (52%)
 Frame = +2

Query: 359 RVSILFGHENRVSTLRVSPDGTAFCSGSWDHTLRVW 394
            V  L GH   V  LR SPDG    SG+ D+ L VW
Sbjct: 35  HVGTLSGHSQEVCGLRWSPDGKYLASGANDNLLCVW 142

 Score = 28.9 bits (63), Expect = 4.2,   Method: Compositional matrix adjust.
 Identities = 12/38 (31%), Positives = 19/38 (50%)
 Frame = +2

Query: 100 TLKGHGNKVLCMDWCKDKRRIVSSSQDGKVIVWDSFTT 137
           TL GH  +V  + W  D + + S + D  + VW +  T
Sbjct: 44  TLSGHSQEVCGLRWSPDGKYLASGANDNLLCVWPAQVT 157

 Score = 26.6 bits (57), Expect(2) = 5.5,   Method: Compositional matrix adjust.
 Identities = 28/111 (25%), Positives = 41/111 (36%), Gaps = 6/111 (5%)
 Frame = +3

Query: 211 LTASGDGTC----ALWDVESGQLLQSFHGHGADVLCLDLAPSETGNTFVSGG-CDKKAMV 265
           L ASG GT       W+  +G  L S        +C  L   E      S G    + ++
Sbjct: 246 LLASGGGTADRHIHFWNCNTGTNLSSVDTKSQ--VCALLWSKEHRELISSHGFAQNQLII 419

Query: 266 WDMRSGQCVQAFETHESDVNSVRYYPSGDAFASGSDDATCRLYD-LRADRE 315
           W   +   V     H + V  +   P G+   S + D T RL+     D+E
Sbjct: 420 WKYPAMSRVAELTGHTARVLHMAMSPDGETVVSAAADETLRLWKCFTVDKE 572

 Score = 20.0 bits (40), Expect(2) = 5.5,   Method: Compositional matrix adjust.
 Identities = 8/21 (38%), Positives = 12/21 (57%)
 Frame = +2

Query: 155 YAPSGCAIACGGLDNKCSVYP 175
           ++P G  +A G  DN   V+P
Sbjct: 83  WSPDGKYLASGANDNLLCVWP 145
>19140
          Length = 573

 Score = 41.2 bits (95), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 38/158 (24%), Positives = 62/158 (39%), Gaps = 6/158 (3%)
 Frame = -3

Query: 194 HTNYLSACSFTNSDMQILTASGDGTCALWDVESGQLLQSFHGHGADVLCLDLAPSETGNT 253
           HT+ + A        Q L+ S DGT  LW +   + + +F  H   V  L    +E+  T
Sbjct: 490 HTDNVKALVLNRDGTQCLSGSSDGTIRLWSLGQQRCVATFRVHDEGVWALQA--NESFTT 317

Query: 254 FVSGGCDKKAMVWDMRSGQCVQAFETHESDVNSVRYYPSGDAFASGSDDATC------RL 307
             SGG D +    D+++    +     ++ V  +   P+       +   +C      RL
Sbjct: 316 LYSGGRDHQVWATDIKNPDNRELICEEKAPVLKLELTPTDPPSLWVATTDSCIKNWPVRL 137

Query: 308 YDLRADREVAIYSKESIIFGASSVDFSLSGRLLFAGYN 345
            + RA  E   Y  + I   A+  DF + G      YN
Sbjct: 136 PNPRASGE---YDNDRIHPTATQPDFVIKGGPSIRQYN 32

 Score = 30.8 bits (68), Expect = 1.0,   Method: Compositional matrix adjust.
 Identities = 15/33 (45%), Positives = 21/33 (63%)
 Frame = -3

Query: 363 LFGHENRVSTLRVSPDGTAFCSGSWDHTLRVWA 395
           L GH + V  L ++ DGT   SGS D T+R+W+
Sbjct: 499 LKGHTDNVKALVLNRDGTQCLSGSSDGTIRLWS 401
>04358
          Length = 2430

 Score = 40.8 bits (94), Expect = 8e-04,   Method: Compositional matrix adjust.
 Identities = 47/200 (23%), Positives = 89/200 (44%), Gaps = 15/200 (7%)
 Frame = +1

Query: 186  AKKKSVAMHTNYLSACSFTNSDMQ-ILTASGDGTCALWDVES--GQLLQSFHGH---GAD 239
            A+  ++  H + +S+  F ++D   I+TAS D T  +WD  +   + +Q F G       
Sbjct: 1393 AQTNTLTGHDDVISSIRFLHTDPGLIMTASHDHTVRIWDPRASVSKEVQRFSGEQNTKCS 1572

Query: 240  VLCLDLAPSET---GNTFVSGGCDKKAMVWDMRSGQCVQAFE-THESDVNSVRYYPSGD- 294
            VL  D+  S+      T +S   D   + WD R  + +  +E +H  D+  V + P+ + 
Sbjct: 1573 VLSCDVNISDRVLCAGTEMSND-DAYLLFWDRRKDKLLGCYEDSHHDDITQVHFGPTSEK 1749

Query: 295  AFASGSDDATCRLYDLRADRE----VAIYSKESIIFGASSVDFSLSGRLLFAGYNDYTIN 350
               +GS D    ++D+    E    ++ Y+ E+ +  A         + ++A  +  + +
Sbjct: 1750 TLLTGSTDGLVNVFDVMQTTEDDALMSTYNTEATVERAGWC--GPQSQQVYAITHMLSWH 1923

Query: 351  VWDVLKGSRVSILFGHENRV 370
            VWD  K   V  L   E ++
Sbjct: 1924 VWDTEKDEDVQQLTDLEQKL 1983

 Score = 34.7 bits (78), Expect = 0.065,   Method: Compositional matrix adjust.
 Identities = 18/81 (22%), Positives = 44/81 (54%), Gaps = 2/81 (2%)
 Frame = +1

Query: 316  VAIYSKES-IIFGASSVDFSLSGRLLFAGYNDYTINVWDVLKGSRVSILFGHENRVSTLR 374
            V++Y  E   + G ++     +  L+ A  +++ + ++   + ++ + L GH++ +S++R
Sbjct: 1264 VSLYKTEPHYVLGLAAQHTGGADSLVAAASSNFMVRLYSRCRLAQTNTLTGHDDVISSIR 1443

Query: 375  -VSPDGTAFCSGSWDHTLRVW 394
             +  D     + S DHT+R+W
Sbjct: 1444 FLHTDPGLIMTASHDHTVRIW 1506

 Score = 28.5 bits (62), Expect = 5.1,   Method: Compositional matrix adjust.
 Identities = 13/41 (31%), Positives = 23/41 (56%), Gaps = 1/41 (2%)
 Frame = +1

Query: 95   MKTRRTLKG-HGNKVLCMDWCKDKRRIVSSSQDGKVIVWDS 134
            +K  R+L G H + V C+ W K  + +V+  +D  + +W S
Sbjct: 2113 VKVVRSLSGGHTDTVRCLHWDKQTQTLVTGGEDSMLCLWSS 2235
>26939
          Length = 388

 Score = 40.4 bits (93), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 18/61 (29%), Positives = 32/61 (52%)
 Frame = +2

Query: 251 GNTFVSGGCDKKAMVWDMRSGQCVQAFETHESDVNSVRYYPSGDAFASGSDDATCRLYDL 310
           G   VS   DK   VWD+R+ +C++    H+    S+ ++ +     SGS D T ++++ 
Sbjct: 2   GKYLVSASDDKTIRVWDLRNKRCMKTLYAHQHFCTSIDFHKAHPYVISGSVDQTVKVWEC 181

Query: 311 R 311
           R
Sbjct: 182 R 184

 Score = 35.8 bits (81), Expect = 0.029,   Method: Compositional matrix adjust.
 Identities = 20/62 (32%), Positives = 33/62 (53%), Gaps = 1/62 (1%)
 Frame = +2

Query: 293 GDAFASGSDDATCRLYDLRADREV-AIYSKESIIFGASSVDFSLSGRLLFAGYNDYTINV 351
           G    S SDD T R++DLR  R +  +Y+ +      +S+DF  +   + +G  D T+ V
Sbjct: 2   GKYLVSASDDKTIRVWDLRNKRCMKTLYAHQHF---CTSIDFHKAHPYVISGSVDQTVKV 172

Query: 352 WD 353
           W+
Sbjct: 173 WE 178

 Score = 35.8 bits (81), Expect = 0.034,   Method: Compositional matrix adjust.
 Identities = 17/58 (29%), Positives = 30/58 (51%)
 Frame = +2

Query: 337 GRLLFAGYNDYTINVWDVLKGSRVSILFGHENRVSTLRVSPDGTAFCSGSWDHTLRVW 394
           G+ L +  +D TI VWD+     +  L+ H++  +++          SGS D T++VW
Sbjct: 2   GKYLVSASDDKTIRVWDLRNKRCMKTLYAHQHFCTSIDFHKAHPYVISGSVDQTVKVW 175
>04088
          Length = 511

 Score = 39.7 bits (91), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 22/81 (27%), Positives = 36/81 (44%)
 Frame = +3

Query: 198 LSACSFTNSDMQILTASGDGTCALWDVESGQLLQSFHGHGADVLCLDLAPSETGNTFVSG 257
           +++ +FT      L +S D T  L D ++G++L  F GH      +D   +      VSG
Sbjct: 39  VTSVTFTRDGQCSLVSSQDNTVRLMDKDTGEMLNEFTGHKHSQYKIDSCLNNEDTLVVSG 218

Query: 258 GCDKKAMVWDMRSGQCVQAFE 278
             D K   WD+   + V   +
Sbjct: 219 SEDGKVYFWDLVEAKLVDTLD 281
>29912
          Length = 510

 Score = 38.9 bits (89), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 29/115 (25%), Positives = 52/115 (45%), Gaps = 1/115 (0%)
 Frame = +3

Query: 281 ESDVNSVRYYPSGDAFASGSDDATCRLYDLRADREVAIYSKESIIFGASSVDFSLSGRLL 340
           E  + +V +   G+  A G+     +++D+   +++   +  +   G+     S +  ++
Sbjct: 9   EEYIGAVSWIKEGNYLALGTSTGEVQVWDVTQQKKLRTMAGHAARVGS----LSWNSFIV 176

Query: 341 FAGYNDYTINVWDV-LKGSRVSILFGHENRVSTLRVSPDGTAFCSGSWDHTLRVW 394
            +G     I+  DV +    V  L GH   V  LR SPDG    SG+ D+ L VW
Sbjct: 177 SSGSRSGNIHHHDVRVADHHVGTLSGHSQEVCGLRWSPDGKYLASGANDNLLCVW 341

 Score = 37.0 bits (84), Expect = 0.013,   Method: Compositional matrix adjust.
 Identities = 29/109 (26%), Positives = 46/109 (42%), Gaps = 3/109 (2%)
 Frame = +3

Query: 197 YLSACSFTNSDMQILTASGDGTCALWDVESGQLLQSFHGHGADVLCLDLAPSETGNTFV- 255
           Y+ A S+      +   +  G   +WDV   + L++  GH A V  L        N+F+ 
Sbjct: 15  YIGAVSWIKEGNYLALGTSTGEVQVWDVTQQKKLRTMAGHAARVGSLSW------NSFIV 176

Query: 256 -SGGCDKKAMVWDMR-SGQCVQAFETHESDVNSVRYYPSGDAFASGSDD 302
            SG         D+R +   V     H  +V  +R+ P G   ASG++D
Sbjct: 177 SSGSRSGNIHHHDVRVADHHVGTLSGHSQEVCGLRWSPDGKYLASGAND 323

 Score = 29.3 bits (64), Expect = 2.7,   Method: Compositional matrix adjust.
 Identities = 21/80 (26%), Positives = 32/80 (40%), Gaps = 11/80 (13%)
 Frame = +3

Query: 100 TLKGHGNKVLCMDWCKDKRRIVSSSQDGKVIVWDSFTT-----------NKEHAVTMPCT 148
           TL GH  +V  + W  D + + S + D  + VW +  T           ++  A      
Sbjct: 243 TLSGHSQEVCGLRWSPDGKYLASGANDNLLCVWPAQVTGGNSTQPLHTFSQHQAAVKALA 422

Query: 149 WVMACAYAPSGCAIACGGLD 168
           W   C + PS   +A GG D
Sbjct: 423 W---CPWQPS--XLASGGGD 467
>15118
          Length = 1074

 Score = 38.5 bits (88), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 40/154 (25%), Positives = 64/154 (41%), Gaps = 6/154 (3%)
 Frame = +3

Query: 248 SETGNTFVSGGCDKKAMVWDMRSGQCVQAFETHESDVNSVRYYPSGDAF------ASGSD 301
           S  GN    G       +++++SG+   +F    + V+ VR     DAF      A G  
Sbjct: 84  SSCGNYVAVGYSSGHLDIYNLQSGKHRGSFGDTVAHVSGVRGVAF-DAFNCLLITAGGDC 260

Query: 302 DATCRLYDLRADREVAIYSKESIIFGASSVDFSLSGRLLFAGYNDYTINVWDVLKGSRVS 361
           D     +  R DR   +  +  +  G S +       +L     D+T++V DV     V 
Sbjct: 261 DIKFWRFGSR-DRARVLLKELKMSEGISRILLHRDSNMLAVVLEDFTVSVIDVDTLRVVR 437

Query: 362 ILFGHENRVSTLRVSPDGTAFCSGSWDHTLRVWA 395
           +  GH N ++ L  S DG    + S D T+R W+
Sbjct: 438 VFSGHSNSITDLSFSGDGRWLITASMDCTVRTWS 539

 Score = 30.8 bits (68), Expect = 0.96,   Method: Compositional matrix adjust.
 Identities = 18/56 (32%), Positives = 30/56 (53%)
 Frame = +3

Query: 194 HTNYLSACSFTNSDMQILTASGDGTCALWDVESGQLLQSFHGHGADVLCLDLAPSE 249
           H+N ++  SF+     ++TAS D T   W +  G+L+  F    A V  L ++PS+
Sbjct: 450 HSNSITDLSFSGDGRWLITASMDCTVRTWSLVHGRLIDCFAVEAA-VTSLTMSPSQ 614
>19863
          Length = 502

 Score = 38.1 bits (87), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 22/58 (37%), Positives = 31/58 (53%)
 Frame = +1

Query: 337 GRLLFAGYNDYTINVWDVLKGSRVSILFGHENRVSTLRVSPDGTAFCSGSWDHTLRVW 394
           G  L +G +D +I VWDV  G +   L GH   V+ +  S D     S S D+T+R+W
Sbjct: 7   GLQLVSGSSDMSIVVWDVENGVQKLRLQGHAGWVNDVHFSQDQCWLLSCSNDNTVRIW 180

 Score = 35.0 bits (79), Expect = 0.053,   Method: Compositional matrix adjust.
 Identities = 19/70 (27%), Positives = 32/70 (45%)
 Frame = +1

Query: 249 ETGNTFVSGGCDKKAMVWDMRSGQCVQAFETHESDVNSVRYYPSGDAFASGSDDATCRLY 308
           + G   VSG  D   +VWD+ +G      + H   VN V +        S S+D T R++
Sbjct: 1   DDGLQLVSGSSDMSIVVWDVENGVQKLRLQGHAGWVNDVHFSQDQCWLLSCSNDNTVRIW 180

Query: 309 DLRADREVAI 318
           ++    ++ I
Sbjct: 181 NIEESDQIPI 210

 Score = 27.7 bits (60), Expect = 7.7,   Method: Compositional matrix adjust.
 Identities = 17/74 (22%), Positives = 32/74 (43%)
 Frame = +1

Query: 208 MQILTASGDGTCALWDVESGQLLQSFHGHGADVLCLDLAPSETGNTFVSGGCDKKAMVWD 267
           +Q+++ S D +  +WDVE+G       GH   V   D+  S+     +S   D    +W+
Sbjct: 10  LQLVSGSSDMSIVVWDVENGVQKLRLQGHAGWV--NDVHFSQDQCWLLSCSNDNTVRIWN 183

Query: 268 MRSGQCVQAFETHE 281
           +     +     H+
Sbjct: 184 IEESDQIPIVMEHK 225
>27270
          Length = 1078

 Score = 36.6 bits (83), Expect = 0.018,   Method: Compositional matrix adjust.
 Identities = 51/193 (26%), Positives = 68/193 (35%), Gaps = 16/193 (8%)
 Frame = +2

Query: 102 KGHGNKVLCMDWCKDKRRIVSSSQDGKVIVWDSFTTNKEHAVTMPCTWVMACAYAPSGCA 161
           KGH   V  M W  D R + SSS DG VI W+    N  H +     W            
Sbjct: 263 KGHSKAVTDMCWRADGRTLYSSSLDGHVIGWN---VNTLHMIE---KW------------ 388

Query: 162 IACGGLDNKCSVYPLTFDKNENMAAKKKSVAMHTNYLSACSFTNSDMQILTASGDGTCAL 221
                                     K +   H      C  ++S  ++LTA  D T  +
Sbjct: 389 --------------------------KATSGRHHGVHCVCLCSSS--RLLTA--DHTIKM 478

Query: 222 WDVESGQLLQSFHGHGADVLCL--DLAPSETGN----------TFVSGGCDKKAMVW--D 267
           WD+ +  +LQ F GH  +V+ L   L PS   N           F +   D+   VW  D
Sbjct: 479 WDLTTKNVLQEFSGHSTEVIKLLPVLKPSSEQNDIGDSNLACYVFSAAAADRTINVWRCD 658

Query: 268 MRSGQ--CVQAFE 278
             S Q   V +FE
Sbjct: 659 SESSQATAVTSFE 697
>07665
          Length = 435

 Score = 35.4 bits (80), Expect = 0.044,   Method: Compositional matrix adjust.
 Identities = 25/96 (26%), Positives = 46/96 (47%), Gaps = 7/96 (7%)
 Frame = -2

Query: 266 WDMRSGQCVQAFETHESDVNSVRYYPSGDAFASGSDDATCRLYDLRADREVAIYSKESII 325
           WD+  G+ +   E H   +N++ + P+   +   +   + +++DL   + V     E + 
Sbjct: 392 WDLNDGKNLYTLE-HNDIINALCFSPNR-YWLCVAYGPSIKIWDLACKKTVEELRPEVVS 219

Query: 326 FGAS-------SVDFSLSGRLLFAGYNDYTINVWDV 354
             +        S+ +S  G+ LFAGY+D TI VW V
Sbjct: 218 PTSKAEQPQCLSLAWSTDGQTLFAGYSDNTIRVWQV 111
>12140
          Length = 727

 Score = 35.0 bits (79), Expect = 0.050,   Method: Compositional matrix adjust.
 Identities = 46/177 (25%), Positives = 69/177 (38%), Gaps = 24/177 (13%)
 Frame = +2

Query: 200 ACSFTNSDMQILTASGDGTCALWDVESGQLLQSFHGHGADVLCLDLAPSETGNT------ 253
           AC  ++  + I++ +GDG    WD    + + + H  G + +    APS   N       
Sbjct: 92  ACGSSDGSLSIISTTGDGN---WD---SKKINNAHTIGCNAV--SWAPSTAPNALFDQSA 247

Query: 254 -------FVSGGCDKKAMVWDMRSGQCV--QAFETHESDVNSVRYYPS----GDAFASGS 300
                  FVSGGCD    +W       V  Q  E H   V  V + PS     +  AS S
Sbjct: 248 RQQPVKRFVSGGCDNLVKIWREDETGWVEDQKLEGHSDWVRDVAWAPSIGLPRNVIASCS 427

Query: 301 DDATCRLYDLRADREVAIYSKESIIFGASS-----VDFSLSGRLLFAGYNDYTINVW 352
            D  CR+     D     ++  S I    S     V +S++G +L     D  + +W
Sbjct: 428 QD--CRVIIWTNDGSSNQWT--SRILNKFSDVVWHVSWSVTGNILAVSGGDNKVTLW 586
>27681
          Length = 465

 Score = 34.7 bits (78), Expect = 0.074,   Method: Compositional matrix adjust.
 Identities = 14/33 (42%), Positives = 19/33 (57%)
 Frame = +3

Query: 245 LAPSETGNTFVSGGCDKKAMVWDMRSGQCVQAF 277
           L  ++ GN  +S G DK  ++WD  SG C Q F
Sbjct: 303 LKWNKRGNYILSAGVDKTTIIWDASSGSCTQQF 401
>33180
          Length = 460

 Score = 34.3 bits (77), Expect = 0.085,   Method: Compositional matrix adjust.
 Identities = 20/68 (29%), Positives = 32/68 (47%)
 Frame = -2

Query: 203 FTNSDMQILTASGDGTCALWDVESGQLLQSFHGHGADVLCLDLAPSETGNTFVSGGCDKK 262
           F++ + +I+  + DG   ++D ES Q       H  DV  +  A  ++     SGG D  
Sbjct: 429 FSSDNTEIVGGANDGCLYVYDRESNQRTLKIDAHDDDVNAVAFA-DDSSQILYSGGDDGL 253

Query: 263 AMVWDMRS 270
             VWD R+
Sbjct: 252 CKVWDRRT 229
>31864
          Length = 545

 Score = 33.9 bits (76), Expect = 0.10,   Method: Compositional matrix adjust.
 Identities = 32/127 (25%), Positives = 54/127 (42%), Gaps = 13/127 (10%)
 Frame = +2

Query: 194 HTNYLSACSFTNSDMQILTASGDGTCALWDVESGQLLQSFHGHGADVLCLDLAPSETGNT 253
           HT  ++    +      +TAS D T  L+D ES   L+++      V    ++P    + 
Sbjct: 47  HTGGINDMQLSKDGTMFVTASKDTTAKLFDSESLMCLKTYKTE-RPVNSAAISPI-LDHV 220

Query: 254 FVSGGCD--------KKAMVWDMRSGQCVQAFE-----THESDVNSVRYYPSGDAFASGS 300
            + GG D         KA  +D R    +   E      H   +NS+ ++P G ++ASG 
Sbjct: 221 VLGGGQDAMEVTTTSTKAGKFDSRFFHLIYEEEFARLKGHFGPINSLAFHPDGKSYASGG 400

Query: 301 DDATCRL 307
           +D   R+
Sbjct: 401 EDGFVRV 421
>17298
          Length = 476

 Score = 33.5 bits (75), Expect = 0.15,   Method: Compositional matrix adjust.
 Identities = 20/76 (26%), Positives = 33/76 (43%)
 Frame = -1

Query: 259 CDKKAMVWDMRSGQCVQAFETHESDVNSVRYYPSGDAFASGSDDATCRLYDLRADREVAI 318
           CD   +  ++ SGQ ++ +  H   VN V++        SGS D T R +D R+     I
Sbjct: 278 CDGVVVGNNVASGQALRKYRDHAGTVNCVKFNEESTVILSGSLDNTVRAWDTRSRSHTPI 99

Query: 319 YSKESIIFGASSVDFS 334
              +      +S+  S
Sbjct: 98  QVLDEATDSVTSIQVS 51
>01805
          Length = 2124

 Score = 33.5 bits (75), Expect = 0.16,   Method: Compositional matrix adjust.
 Identities = 43/188 (22%), Positives = 73/188 (38%), Gaps = 9/188 (4%)
 Frame = -1

Query: 99  RTLKGHGNKVLCMDWCKDKRRIV-SSSQDGKVIVWDSFTTNKEHAVTMPCTWVMACAYAP 157
            ++ GH   VL + W ++ R ++ S+S D  V +WD          T     V  C + P
Sbjct: 594 ESVTGHTQAVLDLSWNRNARHVLASASADTTVALWDLSEGKMAMNFTQHSREVQCCNWHP 415

Query: 158 S-GCAIACGGLDNKCSVY----PLTFDKNENMAAK-KKSVAMHTNYLSACSFTNSDMQIL 211
                +  G  DN   V       T  K+  +  + +K+V  H N L          Q+L
Sbjct: 414 QEEQTLLTGSFDNTVKVVDCRSAETCHKSWTVEGEVEKAVWNHHNPL----------QLL 265

Query: 212 TASGDGTCALWDVESGQLLQSFHGHGADV--LCLDLAPSETGNTFVSGGCDKKAMVWDMR 269
             +  G    +D+   + + S   H + V  +CL    S+     ++   DK   VWD++
Sbjct: 264 ACTDKGMVYCFDIRHEKPVFSVGAHSSCVTGVCLS---SQIPGLMITTSEDKTMKVWDIQ 94

Query: 270 SGQCVQAF 277
             +    F
Sbjct: 93  DDKPTHVF 70
>15337
          Length = 860

 Score = 33.1 bits (74), Expect = 0.18,   Method: Compositional matrix adjust.
 Identities = 23/95 (24%), Positives = 41/95 (43%)
 Frame = -1

Query: 195 TNYLSACSFTNSDMQILTASGDGTCALWDVESGQLLQSFHGHGADVLCLDLAPSETGNTF 254
           T  +S  +F+     +     DG   +++  S +L+ +   +   +LC+  +P   G   
Sbjct: 329 TGAISEFAFSPCSRYLAVVGQDGHLRVFNYNSMELIGTMKSYFGGLLCVCWSPD--GKYI 156

Query: 255 VSGGCDKKAMVWDMRSGQCVQAFETHESDVNSVRY 289
           V+GG D    VW     + V     H+S VN V +
Sbjct: 155 VTGGEDDLVTVWSFHEKRVVCRGHGHKSWVNVVAF 51

 Score = 29.6 bits (65), Expect = 2.0,   Method: Compositional matrix adjust.
 Identities = 13/38 (34%), Positives = 21/38 (55%)
 Frame = -1

Query: 95  MKTRRTLKGHGNKVLCMDWCKDKRRIVSSSQDGKVIVW 132
           M+   T+K +   +LC+ W  D + IV+  +D  V VW
Sbjct: 233 MELIGTMKSYFGGLLCVCWSPDGKYIVTGGEDDLVTVW 120
>01598
          Length = 1545

 Score = 32.3 bits (72), Expect = 0.37,   Method: Compositional matrix adjust.
 Identities = 18/79 (22%), Positives = 39/79 (49%), Gaps = 1/79 (1%)
 Frame = +1

Query: 189  KSVAMHTNYLSACSFT-NSDMQILTASGDGTCALWDVESGQLLQSFHGHGADVLCLDLAP 247
            + ++ H+  ++  S++ + D ++++   D    +WDV+ G  L  F GH   +L    + 
Sbjct: 1282 RELSGHSQRVTDMSWSPHHDARLVSVGYDAEAFVWDVQKGTALAQFKGHMGRLLTCQFSG 1461

Query: 248  SETGNTFVSGGCDKKAMVW 266
             +  +  ++GG D    VW
Sbjct: 1462 LDP-DLVMTGGSDASVHVW 1515

 Score = 31.2 bits (69), Expect = 0.86,   Method: Compositional matrix adjust.
 Identities = 21/62 (33%), Positives = 30/62 (48%), Gaps = 3/62 (4%)
 Frame = +1

Query: 75   LHDVELHQV-AERV-EALGQFVMKTRRTLKGHGNKVLCMDWCKDK-RRIVSSSQDGKVIV 131
            +H V+L  V AER  +     ++ + R L GH  +V  M W      R+VS   D +  V
Sbjct: 1204 IHVVDLASVFAEREGDKETSLILTSLRELSGHSQRVTDMSWSPHHDARLVSVGYDAEAFV 1383

Query: 132  WD 133
            WD
Sbjct: 1384 WD 1389
>10264
          Length = 416

 Score = 32.0 bits (71), Expect = 0.40,   Method: Compositional matrix adjust.
 Identities = 18/79 (22%), Positives = 39/79 (49%), Gaps = 1/79 (1%)
 Frame = -1

Query: 189 KSVAMHTNYLSACSFT-NSDMQILTASGDGTCALWDVESGQLLQSFHGHGADVLCLDLAP 247
           + ++ H+  ++  S++ + D ++++   D    +WDV+ G  L  F GH   +L    + 
Sbjct: 263 RELSGHSQRVTDMSWSPHHDARLVSVGYDAEAFVWDVQKGTALAQFKGHMGRLLTCQFSG 84

Query: 248 SETGNTFVSGGCDKKAMVW 266
            +  +  ++GG D    VW
Sbjct: 83  LDP-DLVMTGGSDASVHVW 30

 Score = 31.2 bits (69), Expect = 0.83,   Method: Compositional matrix adjust.
 Identities = 14/42 (33%), Positives = 20/42 (47%), Gaps = 1/42 (2%)
 Frame = -1

Query: 93  FVMKTRRTLKGHGNKVLCMDWCKDK-RRIVSSSQDGKVIVWD 133
            ++ + R L GH  +V  M W      R+VS   D +  VWD
Sbjct: 281 LILTSLRELSGHSQRVTDMSWSPHHDARLVSVGYDAEAFVWD 156
>27806
          Length = 419

 Score = 32.0 bits (71), Expect = 0.42,   Method: Compositional matrix adjust.
 Identities = 15/49 (30%), Positives = 24/49 (48%)
 Frame = -1

Query: 346 DYTINVWDVLKGSRVSILFGHENRVSTLRVSPDGTAFCSGSWDHTLRVW 394
           D+T  ++ +  G+ V    GH+  V+ +R  P      + S DHT  VW
Sbjct: 362 DHTARIYSIETGACVLTYGGHQGSVNAVRFHPGQDLVLTASGDHTAHVW 216
>21921
          Length = 1341

 Score = 32.0 bits (71), Expect = 0.45,   Method: Compositional matrix adjust.
 Identities = 17/50 (34%), Positives = 26/50 (52%), Gaps = 2/50 (4%)
 Frame = -1

Query: 267 DMRSGQCVQA--FETHESDVNSVRYYPSGDAFASGSDDATCRLYDLRADR 314
           D+R     QA  ++ H   V S+   P+G    SGSDD T R +++ + R
Sbjct: 531 DLRPFPTTQALVYKGHTGIVRSICPDPTGQWLVSGSDDGTIRFWEVSSGR 382

 Score = 29.6 bits (65), Expect = 2.0,   Method: Compositional matrix adjust.
 Identities = 38/181 (20%), Positives = 69/181 (38%), Gaps = 1/181 (0%)
 Frame = -1

Query: 205 NSDMQILTASGDGTCALWDVESGQLLQSFHGHGADVLCLDLAPSETGNTFVSGGCDKKAM 264
           N D Q L         L    + Q L  + GH    +   + P  TG   VSG  D    
Sbjct: 576 NVDPQDLLPKLPKPKDLRPFPTTQAL-VYKGHTG--IVRSICPDPTGQWLVSGSDDGTIR 406

Query: 265 VWDMRSGQCVQAFETHESDVNSVRYYPSGDA-FASGSDDATCRLYDLRADREVAIYSKES 323
            W++ SG+C++  +     V SV + P+      + + + T  L +     ++ + + + 
Sbjct: 405 FWEVSSGRCMKTLQVGGC-VTSVAWNPNPSLCVVAATLNTTVLLINPGLGDKLVVSNTDK 229

Query: 324 IIFGASSVDFSLSGRLLFAGYNDYTINVWDVLKGSRVSILFGHENRVSTLRVSPDGTAFC 383
           ++  +     S S +     +    +NV D   G R+ +   H   VS +     G  F 
Sbjct: 228 LLLASEDQASSSSEKEQPVDWVRTELNVEDYTSGVRLRL--EHPKEVSKVTWHAKGDYFA 55

Query: 384 S 384
           +
Sbjct: 54  T 52
>03734
          Length = 1963

 Score = 31.6 bits (70), Expect = 0.64,   Method: Compositional matrix adjust.
 Identities = 18/51 (35%), Positives = 24/51 (47%)
 Frame = -2

Query: 207  DMQILTASGDGTCALWDVESGQLLQSFHGHGADVLCLDLAPSETGNTFVSG 257
            D+ I++    G    W+ + G  +  F  H ADVL L    SET N F  G
Sbjct: 1860 DLTIVSGDSRGKVCFWNGKQGTRIAHFQSHKADVLTLCADESET-NVFCGG 1711
>03044
          Length = 1952

 Score = 30.4 bits (67), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 13/33 (39%), Positives = 16/33 (48%)
 Frame = -2

Query: 100  TLKGHGNKVLCMDWCKDKRRIVSSSQDGKVIVW 132
            TL  HG +V  +DW     RIV+   D    VW
Sbjct: 1669 TLGEHGQRVTGIDWAPKSNRIVTCGADRNAYVW 1571
>00825
          Length = 1821

 Score = 30.0 bits (66), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 16/62 (25%), Positives = 29/62 (46%)
 Frame = -2

Query: 256  SGGCDKKAMVWDMRSGQCVQAFETHESDVNSVRYYPSGDAFASGSDDATCRLYDLRADRE 315
            SG CD + + W++   Q     + H+  V+ +  + SG  F S   D T + + L  +  
Sbjct: 1820 SGACDGELICWNLPKQQMACRVQAHDGIVHGMAAHSSGQYFFSCGSDKTIKQWSLDPEGT 1641

Query: 316  VA 317
            +A
Sbjct: 1640 IA 1635
>28289
          Length = 349

 Score = 30.0 bits (66), Expect = 1.8,   Method: Composition-based stats.
 Identities = 11/38 (28%), Positives = 22/38 (57%)
 Frame = -1

Query: 95  MKTRRTLKGHGNKVLCMDWCKDKRRIVSSSQDGKVIVW 132
           +   ++L+GH   V  + W +  +++ +S Q G +IVW
Sbjct: 262 LSMNQSLEGHSGAVQVVAWNEHHQKLTTSDQYGLIIVW 149
>30679
          Length = 1025

 Score = 29.6 bits (65), Expect = 2.1,   Method: Compositional matrix adjust.
 Identities = 18/54 (33%), Positives = 30/54 (55%)
 Frame = +1

Query: 339 LLFAGYNDYTINVWDVLKGSRVSILFGHENRVSTLRVSPDGTAFCSGSWDHTLR 392
           LL AG+ DY   VW+V +   V+I+  H + + ++  +  G+ F + S D  LR
Sbjct: 7   LLSAGF-DYKCVVWNVEQAEPVNIVDCHTDTIFSMSWNRXGSMFATTSKDKKLR 165
>31474
          Length = 403

 Score = 29.6 bits (65), Expect = 2.2,   Method: Compositional matrix adjust.
 Identities = 15/47 (31%), Positives = 22/47 (46%), Gaps = 2/47 (4%)
 Frame = -3

Query: 245 LAPSETGNTFVSGGCDKKAMVWDMRSGQ--CVQAFETHESDVNSVRY 289
           L  S  GN   S   D    VW  + G+  C+   E HE++V +V +
Sbjct: 152 LGWSPCGNYLSSASFDATTAVWSRKGGEFECIATLEGHENEVKAVAW 12

 Score = 28.5 bits (62), Expect = 5.2,   Method: Compositional matrix adjust.
 Identities = 20/89 (22%), Positives = 39/89 (43%), Gaps = 2/89 (2%)
 Frame = -3

Query: 154 AYAPSGCAIACGGLDNKCSVYPLTFDKNENMAAKKKSVAMHTNYLSACSFTNSDMQILTA 213
           A+ P+G  +A  G D    ++     + +N   K      HT  + +  ++     + +A
Sbjct: 284 AWNPTGTLLASCGSDKIIKIWG---KEGDNWVCKSTLTDAHTRTVRSLGWSPCGNYLSSA 114

Query: 214 SGDGTCALWDVESGQL--LQSFHGHGADV 240
           S D T A+W  + G+   + +  GH  +V
Sbjct: 113 SFDATTAVWSRKGGEFECIATLEGHENEV 27
>07781
          Length = 1269

 Score = 29.3 bits (64), Expect = 2.8,   Method: Compositional matrix adjust.
 Identities = 28/110 (25%), Positives = 46/110 (41%), Gaps = 3/110 (2%)
 Frame = -2

Query: 209 QILTASGDGTCALWDVESGQLLQSFHGHGADVLCLDLAPSETGNTFVSGGCDK-KAMVWD 267
           +++T+   G   +++VES  + ++      D      A  +     +  G D  K  VWD
Sbjct: 884 RVITSDSAGNLTVFEVESTTVRETSQWRAHDFEAWICAFDQWNTELIYSGSDDCKLKVWD 705

Query: 268 MRSGQC-VQAFETHESDVNSVRYYPSGD-AFASGSDDATCRLYDLRADRE 315
           +R G   V         V S++  P  +   A GS D   RL+D R  R+
Sbjct: 704 LRVGTTPVLTNSRFTMGVTSIQSCPQREHLLAVGSYDENLRLFDTRHMRQ 555
>08679
          Length = 2028

 Score = 28.9 bits (63), Expect = 3.5,   Method: Compositional matrix adjust.
 Identities = 45/200 (22%), Positives = 76/200 (38%), Gaps = 17/200 (8%)
 Frame = -3

Query: 127  GKVIVWDSFTTNKEHAVTMPCTWVMACAYAPSGCAIA--CGGLDNKCSVYPLTFDKNENM 184
            G +  WD  T N++ +V           Y P    I        + CSVY  ++D    +
Sbjct: 1879 GSLSFWDVGTENQDGSVV---------TYRPHSGPIGHIVVPTSDPCSVYTCSYDSTLRL 1727

Query: 185  AAKKKSV---AMHTNYLSACSFTNSDM----QILTASGDGTCALWDVES--GQLLQSFHG 235
               ++ V       N     SF N D      +L A   G  ++ D  +   +  Q++  
Sbjct: 1726 GNFERGVFDLIYSVNXEENNSFRNFDFLSPSSLLLAQFMGDVSIIDTRTYGRKAEQTYTV 1547

Query: 236  HGADVLCLDLAPSETGNTFVSGGCDKKAMVWDMRSGQCVQAFET-----HESDVNSVRYY 290
                +  + + P+   + FV+ G D K  VWD+R     +  E      H   V+S  + 
Sbjct: 1546 CDTYLRSVSVHPTNP-HFFVTAGSDMKXSVWDLRKLSASKGNEPLHSMMHGKTVSSAYFS 1370

Query: 291  P-SGDAFASGSDDATCRLYD 309
            P +G    S S D T  +++
Sbjct: 1369 PLTGARILSCSADDTLNVFN 1310
>07151
          Length = 512

 Score = 28.9 bits (63), Expect = 4.2,   Method: Compositional matrix adjust.
 Identities = 12/36 (33%), Positives = 20/36 (55%)
 Frame = -1

Query: 108 VLCMDWCKDKRRIVSSSQDGKVIVWDSFTTNKEHAV 143
           V C D+ KDK  IV+   D  + +W+ + + K  A+
Sbjct: 155 VKCFDFSKDKNIIVTGGMDRIIRLWNPYVSQKPTAM 48
>15972
          Length = 1069

 Score = 28.5 bits (62), Expect = 5.4,   Method: Compositional matrix adjust.
 Identities = 13/30 (43%), Positives = 16/30 (53%)
 Frame = +3

Query: 365 GHENRVSTLRVSPDGTAFCSGSWDHTLRVW 394
           GH+  V  L V P G    + S D TLR+W
Sbjct: 231 GHKGPVRHLAVHPSGKLTLTVSQDRTLRLW 320
>30297
          Length = 822

 Score = 28.1 bits (61), Expect = 6.2,   Method: Compositional matrix adjust.
 Identities = 19/79 (24%), Positives = 34/79 (43%), Gaps = 10/79 (12%)
 Frame = -1

Query: 198 LSACSFTNSDMQILTASGDGTCALWDV----------ESGQLLQSFHGHGADVLCLDLAP 247
           +SA +   ++  + +A   G   +WD+          +S  ++QS+ GH   V CLDL  
Sbjct: 375 VSAMATNKANTLLYSADSLGFIYVWDISQYCLETPETDSPDVIQSWRGHVESVSCLDLV- 199

Query: 248 SETGNTFVSGGCDKKAMVW 266
            E     ++   D    +W
Sbjct: 198 -EQNKVLLTSAADCTVRMW 145
>19473
          Length = 424

 Score = 27.7 bits (60), Expect = 7.9,   Method: Compositional matrix adjust.
 Identities = 16/32 (50%), Positives = 19/32 (59%), Gaps = 2/32 (6%)
 Frame = -2

Query: 183 NMAAKKKSVAMHTNYLS--ACSFTNSDMQILT 212
           NM  K   V  HT++    AC FTN+DM ILT
Sbjct: 96  NMYRKSGYVQYHTHFQMNVACLFTNNDM*ILT 1
>25930
          Length = 419

 Score = 27.7 bits (60), Expect = 8.0,   Method: Compositional matrix adjust.
 Identities = 10/31 (32%), Positives = 18/31 (58%)
 Frame = +1

Query: 103 GHGNKVLCMDWCKDKRRIVSSSQDGKVIVWD 133
           G  + +  ++W  D  R++S S+ G + VWD
Sbjct: 190 GQDDSIKNLNWSLDATRLISVSESGTLQVWD 282
>16199
          Length = 694

 Score = 27.7 bits (60), Expect = 8.5,   Method: Compositional matrix adjust.
 Identities = 12/44 (27%), Positives = 22/44 (50%)
 Frame = +2

Query: 333 FSLSGRLLFAGYNDYTINVWDVLKGSRVSILFGHENRVSTLRVS 376
           F   G +   G  D  I +WD+ + + V+   GH+  V+++  S
Sbjct: 95  FHPDGLIFATGTEDSVIKIWDLKERANVANFQGHQGPVTSISFS 226
>12076
          Length = 949

 Score = 27.7 bits (60), Expect = 8.8,   Method: Compositional matrix adjust.
 Identities = 10/23 (43%), Positives = 16/23 (69%)
 Frame = -1

Query: 300 SDDATCRLYDLRADREVAIYSKE 322
           SDDA+CR Y L+ +  V +Y ++
Sbjct: 283 SDDASCRFYTLKENTAVQVYDRQ 215
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|7710018|ref|NP_038543.1| stomatin [Mus musculus]
         (284 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

05561                                                                 193   5e-50
07016                                                                 131   8e-47
12912                                                                  75   2e-14
00139                                                                  29   1.8  
00594                                                                  29   2.3  
25186                                                                  28   3.9  
29376                                                                  28   6.2  
>05561
          Length = 1025

 Score =  193 bits (491), Expect = 5e-50,   Method: Compositional matrix adjust.
 Identities = 96/154 (62%), Positives = 117/154 (75%)
 Frame = +3

Query: 127 QNATLAVANITNADSATRLLAQTTLRNALGTKNLSQILSDREEIAHHMQSTLDDATDDWG 186
           Q+AT +V N+ +A  +T+LLA TTLRN LGTKNL++ILSDRE I+H MQS+LDDATD WG
Sbjct: 3   QDATASVNNVEDAARSTQLLAATTLRNVLGTKNLAEILSDREAISHFMQSSLDDATDPWG 182

Query: 187 IKVERVEIKDVKLPVQLQXXXXXXXXXXXXXXXXXXXXXGEMNASRALKEASMVITESPA 246
           IKVERVE+KDV+LPVQLQ                     GE  ASRALK+A+ ++ ESPA
Sbjct: 183 IKVERVEVKDVRLPVQLQRAMAAEAEAAREARAKVIAAEGEQKASRALKDAADIMIESPA 362

Query: 247 ALQLRYLQTLTTIAAEKNSTIVFPLPVDMLQGIM 280
           ALQLRYLQTL +I+AEKNSTI+FPLP+DML+G M
Sbjct: 363 ALQLRYLQTLNSISAEKNSTIIFPLPMDMLKGFM 464
>07016
          Length = 1481

 Score =  131 bits (329), Expect(2) = 8e-47,   Method: Compositional matrix adjust.
 Identities = 64/110 (58%), Positives = 77/110 (70%)
 Frame = +3

Query: 127 QNATLAVANITNADSATRLLAQTTLRNALGTKNLSQILSDREEIAHHMQSTLDDATDDWG 186
           QNAT+ + N+ NA+ +TRLLA TTLRN LGT+NL++ILSDRE I+H MQ+TLDDAT  WG
Sbjct: 3   QNATMCITNVANANRSTRLLAATTLRNVLGTRNLAEILSDREAISHFMQTTLDDATHPWG 182

Query: 187 IKVERVEIKDVKLPVQLQXXXXXXXXXXXXXXXXXXXXXGEMNASRALKE 236
           +KVERVE+KDV+LPVQLQ                     GE  ASRALKE
Sbjct: 183 VKVERVEVKDVRLPVQLQRAMAAEAEAAREARAKVIAAEGEQKASRALKE 332

 Score = 73.6 bits (179), Expect(2) = 8e-47,   Method: Compositional matrix adjust.
 Identities = 33/46 (71%), Positives = 42/46 (91%)
 Frame = +2

Query: 235 KEASMVITESPAALQLRYLQTLTTIAAEKNSTIVFPLPVDMLQGIM 280
           + A+ +ITESPAALQLRYLQTL +I+AEKNSTIVFPLP+D+++G M
Sbjct: 326 ERAADIITESPAALQLRYLQTLNSISAEKNSTIVFPLPMDLMKGFM 463
>12912
          Length = 465

 Score = 75.5 bits (184), Expect = 2e-14,   Method: Compositional matrix adjust.
 Identities = 38/56 (67%), Positives = 45/56 (80%), Gaps = 1/56 (1%)
 Frame = +1

Query: 226 GEMNASRALKEASMVITESPAALQLRYLQTLTTIAAEKNSTIVFPL-PVDMLQGIM 280
           GE  ASRALKEA+ ++ ESPAALQLRYLQTL +I+AEKNSTI  PL P  M++G M
Sbjct: 259 GEQKASRALKEAADIMVESPAALQLRYLQTLNSISAEKNSTITLPLAPWTMMKGFM 426
>00139
          Length = 1653

 Score = 29.3 bits (64), Expect = 1.8,   Method: Compositional matrix adjust.
 Identities = 11/24 (45%), Positives = 16/24 (66%)
 Frame = -1

Query: 73  QGGAKGPGLFFILPCTDSLIKVDM 96
            GGA+GPGL   LPC  S +++ +
Sbjct: 756 NGGARGPGLKIALPCRSSPVRLAL 685
>00594
          Length = 2514

 Score = 28.9 bits (63), Expect = 2.3,   Method: Compositional matrix adjust.
 Identities = 11/30 (36%), Positives = 18/30 (60%)
 Frame = -2

Query: 34  LVAASFFFVIITFPISIWICIKIVKEYERV 63
           L+  SF+FV+  FP   ++C+ +   Y RV
Sbjct: 383 LIFLSFYFVLFIFPCFAFVCLWVCVLYSRV 294
>25186
          Length = 1389

 Score = 28.1 bits (61), Expect = 3.9,   Method: Compositional matrix adjust.
 Identities = 13/28 (46%), Positives = 19/28 (67%)
 Frame = +1

Query: 22  NSKTELGACGWILVAASFFFVIITFPIS 49
           NSK E   C WI++A  FF ++ T+P+S
Sbjct: 94  NSKHEYFYCAWIVLA--FFIILGTYPMS 171
>29376
          Length = 550

 Score = 27.7 bits (60), Expect = 6.2,   Method: Compositional matrix adjust.
 Identities = 30/114 (26%), Positives = 52/114 (45%), Gaps = 7/114 (6%)
 Frame = +1

Query: 17  ESFRENSKTELGACGWILVAASFFFVIITFPISIWICIKIVKE-----YERVIIFRLGRI 71
            ++R +   E+ ACG + V  SFF   I  P    +   +V++      +   +F  G +
Sbjct: 16  HNYRIDCNQEMFACGMVSVVCSFFSGFIAGP---SVSRSMVQDGAGGKTQVASLFAAGLV 186

Query: 72  LQG-GAKGPGLFFILPCT-DSLIKVDMRTISFDIPPQEVLTKDSVTISVDGVVY 123
           L      GP  +F+  C   ++I V++R+I F +     L + S    VDG V+
Sbjct: 187 LVVIMVLGPYFYFLPKCVLAAIIIVNLRSIFFRLLAVPALCRQS---PVDGAVW 339
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|9910288|ref|NP_064371.1| intestinal cell kinase [Mus
musculus]
         (629 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

01060                                                                 194   8e-50
01707                                                                 176   2e-44
14126                                                                 176   2e-44
29581                                                                 176   4e-44
01966                                                                 103   1e-40
01756                                                                 157   2e-38
04591                                                                 146   2e-35
32000                                                                 117   1e-26
04138                                                                 117   2e-26
13592                                                                 105   5e-23
00300                                                                  99   5e-21
06405                                                                  97   3e-20
12721                                                                  91   1e-18
28638                                                                  67   8e-18
18921                                                                  87   1e-17
15910                                                                  86   4e-17
21808                                                                  84   2e-16
03240                                                                  83   4e-16
09606                                                                  79   5e-15
19301                                                                  78   1e-14
03294                                                                  76   4e-14
01718                                                                  75   7e-14
17975                                                                  74   2e-13
23319                                                                  73   3e-13
03508                                                                  73   4e-13
19761                                                                  69   5e-12
09007                                                                  67   2e-11
32359                                                                  62   2e-11
01392                                                                  67   2e-11
13212                                                                  67   2e-11
14477                                                                  66   4e-11
18287                                                                  66   4e-11
30755                                                                  65   6e-11
27405                                                                  65   1e-10
26560                                                                  65   1e-10
18484                                                                  65   1e-10
00392                                                                  64   1e-10
27546                                                                  63   4e-10
31489                                                                  62   5e-10
18401                                                                  62   5e-10
19094                                                                  62   5e-10
14420                                                                  62   6e-10
14116                                                                  60   3e-09
07940                                                                  60   3e-09
31885                                                                  59   7e-09
12453                                                                  58   1e-08
04852                                                                  58   1e-08
01106                                                                  57   2e-08
13066                                                                  57   2e-08
21079                                                                  57   2e-08
11780                                                                  53   5e-08
20640                                                                  55   7e-08
17300                                                                  55   1e-07
36481                                                                  54   2e-07
26711                                                                  53   3e-07
24241                                                                  52   1e-06
20559                                                                  52   1e-06
16003                                                                  51   1e-06
11404                                                                  51   2e-06
29360                                                                  50   4e-06
00715                                                                  48   9e-06
13078                                                                  47   2e-05
22005                                                                  47   3e-05
11185                                                                  47   3e-05
26009                                                                  46   4e-05
21800                                                                  45   9e-05
12786                                                                  44   1e-04
28157                                                                  44   1e-04
07836                                                                  44   2e-04
02638                                                                  44   2e-04
21433                                                                  44   2e-04
07291                                                                  43   4e-04
16708                                                                  43   4e-04
18481                                                                  43   5e-04
18996                                                                  41   0.001
17253                                                                  41   0.002
37602                                                                  40   0.003
00638                                                                  37   0.023
37063                                                                  37   0.023
05084                                                                  37   0.026
31757                                                                  36   0.057
17806                                                                  35   0.070
18929                                                                  31   1.8  
29722                                                                  30   2.8  
>01060
          Length = 1800

 Score =  194 bits (494), Expect = 8e-50,   Method: Compositional matrix adjust.
 Identities = 105/293 (35%), Positives = 173/293 (59%), Gaps = 9/293 (3%)
 Frame = +1

Query: 1   MNRYTTIKQLGDGTYGSVLLGRSIESGELIAIKKMK-RKFYSWEECMNLREVKSLKKLNH 59
           ++  T  +++G+GTYG V   R   +G  +A+KK++ R          +RE+  L++L H
Sbjct: 70  LSDLTDFQKIGEGTYGVVYKCRHRATGRKLAMKKIRLRGSEDGVPSSAIREIAMLRELRH 249

Query: 60  ANIVKLKEVIRENDHLYFIFEYMKENLYQLIKERNKLFPESAI------RNIMYQILQGL 113
            NIV L++VI E++ L+ +FE++  +L   I +    FPE  +      ++ ++QI+ G+
Sbjct: 250 TNIVCLEDVIMEDERLFLVFEFLSMDLKMYIDK----FPEGVVLDRRLVKSYVFQIVTGI 417

Query: 114 AFIHKHGFFHRDLKPENLLCMGPELVKIADFGLAREIRSRP--PYTDYVSTRWYRAPEVL 171
            F H+    HRDLKP+NLL      +KIADFG+AR   + P   YT  V T WYRAPE+L
Sbjct: 418 XFCHQRRIVHRDLKPQNLLINHTGAIKIADFGMARTF-ALPVRAYTHEVVTLWYRAPEIL 594

Query: 172 LRSTNYSSPIDIWAVGCIMAEVYTLRPLFPGASEIDTIFKICQVLGTPKKTDWPEGYQLS 231
           + ++ YS+P+D+W++G I A++    P+F G SEID +FKI +++GTP +  WPE ++L 
Sbjct: 595 MGASKYSTPVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIFRIIGTPTEQTWPEFHKL- 771

Query: 232 SAMNFLWPQCIPNNLKTLIPNASSEAIQLLRDLLQWDPKKRPTASQALRYPYF 284
            A N ++P      L   + +  S  + L+   L+ DP +R +  + L++ YF
Sbjct: 772 PAFNGMFPLWKEGKLSETLTDLDSLGLDLIERTLKCDPAQRISCKKMLQHAYF 930
>01707
          Length = 757

 Score =  176 bits (447), Expect = 2e-44,   Method: Compositional matrix adjust.
 Identities = 91/224 (40%), Positives = 138/224 (61%), Gaps = 7/224 (3%)
 Frame = +1

Query: 1   MNRYTTIKQLGDGTYGSVLLGRSIESGELIAIKKMKRKFYSWEEC-----MNLREVKSLK 55
           M +Y  I ++G+G+YG V   R+ E+ +L+AIKK    F   E+      + +RE++ LK
Sbjct: 61  MEKYEKIGKIGEGSYGVVFKCRNKETSQLVAIKK----FVESEDDPLIKKIAMREIRMLK 228

Query: 56  KLNHANIVKLKEVIRENDHLYFIFEYMKENLYQLIKERNKLFPESAIRNIMYQILQGLAF 115
           +L H N+V+L EV R    L+ +F+Y+   L   +    +  PE  ++ I+YQ L  + F
Sbjct: 229 QLKHPNLVRLIEVFRRKKRLHLVFDYVDHTLLNELDRYPRGLPEPMVKRIIYQTLLAVNF 408

Query: 116 IHKHGFFHRDLKPENLLCMGPELVKIADFGLAREIRSRP--PYTDYVSTRWYRAPEVLLR 173
            H++   HRD+KPEN+L      VK+ DFG AR I + P   YTDYV+TRWYRAPE+L+ 
Sbjct: 409 CHQYNTIHRDVKPENILITRQGQVKLCDFGFAR-ILTGPGDEYTDYVATRWYRAPELLVG 585

Query: 174 STNYSSPIDIWAVGCIMAEVYTLRPLFPGASEIDTIFKICQVLG 217
            T Y  P+D+WA+GC+ AE+ T + L+PG S++D +  I + LG
Sbjct: 586 DTQYGPPVDVWAIGCVFAELLTGQALWPGRSDVDQLHLIRKTLG 717
>14126
          Length = 1265

 Score =  176 bits (446), Expect = 2e-44,   Method: Compositional matrix adjust.
 Identities = 108/297 (36%), Positives = 173/297 (58%), Gaps = 14/297 (4%)
 Frame = +3

Query: 3   RYTTIKQLGDGTYGSVLLGRSIES-GELIAIKKMKRKFYSWEE---CMNLREVKSLKKLN 58
           +Y  +  +G+G YG+V   R + + GE +A+K+++    + EE    M +RE+  LK+L 
Sbjct: 192 KYEEVAVIGNGAYGTVYKARDLRNQGEFVAMKRIR--LNNTEEGMPMMAIREISMLKQLE 365

Query: 59  ---HANIVKLKEV----IREND-HLYFIFEYMKENLYQLIKE--RNKLFPESAIRNIMYQ 108
              H N+V+L +V    I + +  L  +FEY++ +L   + +     L P+  I+++M Q
Sbjct: 366 QYEHPNVVRLLDVSHNTITDREIRLNLVFEYIEHDLATYLAKCPSPGLGPDR-IKDLMLQ 542

Query: 109 ILQGLAFIHKHGFFHRDLKPENLLCMGPELVKIADFGLAREIRSRPPYTDYVSTRWYRAP 168
           +L G+ F+H +   HRDLKP+NLL      +K+ADFGLAR        T  V T WYR+P
Sbjct: 543 LLNGVDFLHSNRIVHRDLKPQNLLISKDGRLKLADFGLARIYSFHMALTTVVVTLWYRSP 722

Query: 169 EVLLRSTNYSSPIDIWAVGCIMAEVYTLRPLFPGASEIDTIFKICQVLGTPKKTDWPEGY 228
           EVL+++  Y + +DIW+ GCI AE++T R LF G+SE D + KI +V+G P   DWPEG 
Sbjct: 723 EVLMQA-EYGTSVDIWSCGCIFAELFTRRALFKGSSEFDQLKKIFEVIGLPPAGDWPEG- 896

Query: 229 QLSSAMNFLWPQCIPNNLKTLIPNASSEAIQLLRDLLQWDPKKRPTASQALRYPYFQ 285
            +S   N   P   P  L+TL+P    +A  L+  +L +   +R ++ ++L +PY +
Sbjct: 897 -VSVHRNSFRPTP-PVPLQTLVPEMDPQAKDLMEKMLVFKSGRRISSRESLLHPYLR 1061
>29581
          Length = 1278

 Score =  176 bits (445), Expect = 4e-44,   Method: Compositional matrix adjust.
 Identities = 96/235 (40%), Positives = 136/235 (57%), Gaps = 3/235 (1%)
 Frame = -2

Query: 54   LKKLNHANIVKLKEVI--RENDHLYFIFEYMKENLYQLIKERNKLFPESAIRNIMYQILQ 111
            L  L H NIV+L+EV+  +  D L+ + EY +++L  L+      F ES ++ I+ Q+L+
Sbjct: 1193 LLNLRHQNIVQLQEVVVGKSLDSLFLVMEYCEQDLASLLDNMPAPFSESQVKCIVLQLLK 1014

Query: 112  GLAFIHKHGFFHRDLKPENLLCMGPELVKIADFGLAREI-RSRPPYTDYVSTRWYRAPEV 170
            GL ++H+    HRDLK  NLL      VKIADFGLAR   + + P T  V T WYRAPE+
Sbjct: 1013 GLRYLHEAFIIHRDLKVSNLLMTDKGCVKIADFGLARNYGKPQKPMTPKVVTLWYRAPEL 834

Query: 171  LLRSTNYSSPIDIWAVGCIMAEVYTLRPLFPGASEIDTIFKICQVLGTPKKTDWPEGYQL 230
            L  S  +S+ ID+W+ GCI+ E+   +PL PG S++  I  I ++LGTP  T WP   QL
Sbjct: 833  LFGSKTHSTAIDMWSAGCILGELLGHKPLMPGRSDLQQIELIMELLGTPNDTIWPGFSQL 654

Query: 231  SSAMNFLWPQCIPNNLKTLIPNASSEAIQLLRDLLQWDPKKRPTASQALRYPYFQ 285
             +   F   +   NNL+   P  S   I+LL  L  + P+KR TA   L + YF+
Sbjct: 653  PAFEQFTLKKQPYNNLRHTFPWLSESGIRLLNGLFMYHPQKRATAEDCLEHSYFK 489
>01966
          Length = 1735

 Score =  103 bits (257), Expect(2) = 1e-40,   Method: Compositional matrix adjust.
 Identities = 59/158 (37%), Positives = 93/158 (58%), Gaps = 11/158 (6%)
 Frame = -1

Query: 26   SGELIAIKKMK-RKFYSWEECMNLREVKSLKKLNHANIVKLKEVIRENDHLYFIFEYMKE 84
            +G  +A+KK++ R          +RE+  L++L H NIV L++VI E++ L+ +FE++  
Sbjct: 1639 TGRKLAMKKIRLRGSEDGVPSSAIREIAMLRELRHTNIVCLEDVIMEDERLFLVFEFLSM 1460

Query: 85   NLYQLIKERNKLFPESAI------RNIMYQILQGLAFIHKHGFFHRDLKPENLLCMGPEL 138
            +L   I +    FPE  +      ++ ++QI+ G+ F H+    HRDLKP+NLL      
Sbjct: 1459 DLKMYIDK----FPEGVVLDRRLVKSYVFQIVTGINFCHQRRIVHRDLKPQNLLINHTGA 1292

Query: 139  VKIADFGLARE----IRSRPPYTDYVSTRWYRAPEVLL 172
            +KIADFG+AR     +R+   YT  V T WYRAPE+L+
Sbjct: 1291 IKIADFGMARTFALPVRA---YTHEVVTLWYRAPEILM 1187

 Score = 82.0 bits (201), Expect(2) = 1e-40,   Method: Compositional matrix adjust.
 Identities = 38/111 (34%), Positives = 67/111 (60%)
 Frame = -3

Query: 174  STNYSSPIDIWAVGCIMAEVYTLRPLFPGASEIDTIFKICQVLGTPKKTDWPEGYQLSSA 233
            ++ YS+P+D+W++G I A++    P+F G SEID +FKI +++GTP +  WPE ++L  A
Sbjct: 1184 ASKYSTPVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIFRIIGTPTEQTWPEFHKL-PA 1008

Query: 234  MNFLWPQCIPNNLKTLIPNASSEAIQLLRDLLQWDPKKRPTASQALRYPYF 284
             N ++P      L   + +  S  + L+   L+ DP +R +  + L++ YF
Sbjct: 1007 FNGMFPLWKEGKLSETLTDLDSLGLDLIERTLKCDPAQRISCKKMLQHAYF 855
>01756
          Length = 1858

 Score =  157 bits (396), Expect = 2e-38,   Method: Compositional matrix adjust.
 Identities = 99/303 (32%), Positives = 157/303 (51%), Gaps = 21/303 (6%)
 Frame = -3

Query: 3    RYTTIKQLGDGTYGSVLLGRSIESGELIAIKKM-----KRKFYSWEECMNLREVKSLKKL 57
            +Y  + ++G GT+G V   R  ++ +++A+KK+     K  F        LRE+K L+ L
Sbjct: 1739 KYEKLAKIGQGTFGEVFKARCKKTKQVVAMKKVLMDNEKEGF----PITALREIKILQLL 1572

Query: 58   NHANIVKLKEVI--------RENDHLYFIFEYMKENLYQLIKERNKLFPESAIRNIMYQI 109
            NH N+V L E+         R     Y +FE+ + +L  L+   + +F    I+ +M Q+
Sbjct: 1571 NHENVVDLIEICSTKATSANRYKSMFYLVFEFCEHDLAGLLSNMSVVFNLPEIKEVMKQL 1392

Query: 110  LQGLAFIHKHGFFHRDLKPENLLCMGPELVKIADFGLAR--EIRSRPP--YTDYVSTRWY 165
            + GL +IH++   HRD+K  N+L     ++K+ADFGLAR   +  R P  YT+ V T WY
Sbjct: 1391 MNGLYYIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRVVTLWY 1212

Query: 166  RAPEVLLRSTNYSSPIDIWAVGCIMAEVYTLRPLFPGASEIDTIFKICQVLGTPKKTDWP 225
            R PE+LL   NYS+ ID W  GCIMAE++T  P+  G +E + +  I Q+ G+     WP
Sbjct: 1211 RPPELLLGDRNYSTAIDQWGAGCIMAEMWTRNPIMQGTTEQNQLTLITQLCGSITPEVWP 1032

Query: 226  EGYQLSSAMNFLWPQC----IPNNLKTLIPNASSEAIQLLRDLLQWDPKKRPTASQALRY 281
               +L    +   PQ     +   L+  I +A +  +      L   P KR  + +AL +
Sbjct: 1031 GVERLELYNSLDLPQGNKRKVKERLRYYIKDAYALDLLDKLLALD--PGKRVNSDEALSH 858

Query: 282  PYF 284
             +F
Sbjct: 857  DFF 849
>04591
          Length = 1117

 Score =  146 bits (369), Expect = 2e-35,   Method: Compositional matrix adjust.
 Identities = 85/249 (34%), Positives = 127/249 (51%), Gaps = 10/249 (4%)
 Frame = -2

Query: 48   LREVKSLKKLNHANIVKLKEVI--------RENDHLYFIFEYMKENLYQLIKERNKLFPE 99
            LRE+K L++L H N+V+L+E+         R     Y IFEY   +L  L+      F  
Sbjct: 1077 LREIKILQQLEHENVVQLQEICHTQAGPYNRYKSTFYLIFEYCDYDLAGLLNNLRVKFSL 898

Query: 100  SAIRNIMYQILQGLAFIHKHGFFHRDLKPENLLCMGPELVKIADFGLAREIRSRPPYTDY 159
            +  +N+M Q+L GL +IH     HRD+K  N+L     ++K+ADFGL+R        T+ 
Sbjct: 897  ADKKNLMSQLLNGLFYIHTKQILHRDIKAANILLTRDGVLKLADFGLSRPWVKSKRLTNR 718

Query: 160  VSTRWYRAPEVLLRSTNYSSPIDIWAVGCIMAEVYTLRPLFPGASEIDTIFKICQVLGTP 219
            V T WYR PE+LL    Y   ID+W VGCIMAE+++ +PL  G SE   +  I  + G+ 
Sbjct: 717  VVTLWYRPPELLLGEREYGPEIDMWGVGCIMAEMWSRKPLMQGRSEQHQLSLITDLCGSL 538

Query: 220  KKTDWPEGYQLSSAMNFLWPQCIPNNLKTLIPN--ASSEAIQLLRDLLQWDPKKRPTASQ 277
                WP   +L        PQ  P  +K  + +   + E  +L+   L+ DP +R     
Sbjct: 537  NAEVWPGVTKLELYGKLDLPQGKPRKVKERMLDLLKNKEGAELIDIFLRLDPGQRMNCDN 358

Query: 278  ALRYPYFQI 286
            AL + +F +
Sbjct: 357  ALSHDFFWV 331
>32000
          Length = 644

 Score =  117 bits (294), Expect = 1e-26,   Method: Compositional matrix adjust.
 Identities = 67/153 (43%), Positives = 94/153 (61%), Gaps = 6/153 (3%)
 Frame = -1

Query: 139 VKIADFGLARE----IRSRPPYTDYVSTRWYRAPEVLLRSTNYSSPIDIWAVGCIMAEVY 194
           +KIADFGLAR     +R+   YT  V T WYRAPE+LL    YS P+DIW++GCI  E+ 
Sbjct: 572 MKIADFGLARVFGLPVRT---YTHEVITLWYRAPEILLGCRFYSVPVDIWSLGCIFVEMM 402

Query: 195 TLRPLFPGASEIDTIFKICQVLGTPKKTDWPEGYQLSSAMNFL--WPQCIPNNLKTLIPN 252
           T R LFPG SEID +++I + LGTP +  WP   +L         WP     NL+T++ +
Sbjct: 401 TRRALFPGDSEIDQLYRIFRTLGTPDEKVWPGVSKLPDYKPTFPKWPL---KNLETVV-S 234

Query: 253 ASSEAIQLLRDLLQWDPKKRPTASQALRYPYFQ 285
            S   + LL+ +L ++P +R +A  A+R+PYF 
Sbjct: 233 LSKVGLDLLKRMLTYNPNRRISARSAMRHPYFN 135
>04138
          Length = 800

 Score =  117 bits (293), Expect = 2e-26,   Method: Compositional matrix adjust.
 Identities = 68/185 (36%), Positives = 100/185 (54%), Gaps = 10/185 (5%)
 Frame = +1

Query: 113 LAFIHKHGFFHRDLKPENLLCMGPELVKIADFGLAR--EIRSRPP--YTDYVSTRWYRAP 168
           L +IH++   HRD+K  N+L     ++K+ADFGLAR   +  R P  YT+ V T WYR P
Sbjct: 52  LYYIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRVVTLWYRPP 231

Query: 169 EVLLRSTNYSSPIDIWAVGCIMAEVYTLRPLFPGASEIDTIFKICQVLGTPKKTDWPEGY 228
           E+LL   NYS+ ID W  GCIMAE++T  P+  G +E + +  I Q+ G+     WP   
Sbjct: 232 ELLLGDRNYSTAIDQWGAGCIMAEMWTRNPIMQGTTEQNQLTLITQLCGSITPEVWPGVT 411

Query: 229 QLSSAMNFLWPQCIPNNLKTLIPNASSE------AIQLLRDLLQWDPKKRPTASQALRYP 282
           QLS  M       +    K +I +  +        + L   LL+ DP +R +A +AL + 
Sbjct: 412 QLS--MYHQIKGALAAGRKNIIRDRFARILKDPYGLDLFERLLKMDPSQRISADEALNHD 585

Query: 283 YFQIG 287
           +F +G
Sbjct: 586 FFWVG 600
>13592
          Length = 980

 Score =  105 bits (262), Expect = 5e-23,   Method: Compositional matrix adjust.
 Identities = 80/288 (27%), Positives = 132/288 (45%), Gaps = 9/288 (3%)
 Frame = +2

Query: 9   QLGDGTYGSVLLGRSIESGELIAIKKMKRKFYSWEECMNL-REVKSLKKLNHANIVKLKE 67
           ++G G +G V    +  +GEL+A+K++  +        N+  E+K L+ + H N+V+   
Sbjct: 5   KIGQGRFGKVYTAVNNNTGELMAMKEIAIQPGETRALKNVAEELKILEGIKHKNLVRYYG 184

Query: 68  VIRENDHLYFIFEYMKENLYQLIKERNKLFPESAIRNIMYQILQGLAFIHKHGFFHRDLK 127
           +    + L    E   E   + + E     PE+  R    Q+L G+A +HKHG  HRD+K
Sbjct: 185 IEVHREELLIFMELCSEGTLESLVELTGGLPEALSRRFTAQLLSGVAELHKHGIVHRDIK 364

Query: 128 PENL-LCMGPELVKIADFGLAREIRSRPPY----TDYVSTRWYRAPEVLLR--STNYSSP 180
             N+ L  G   +K+ DFG A +I++          YV T+ Y APEV  +  S  +   
Sbjct: 365 TANIFLVDGSNSLKLGDFGSAVKIQAHTTVPGELQGYVGTQAYMAPEVFTKTNSDGHGRL 544

Query: 181 IDIWAVGCIMAEVYT-LRPLFPGASEIDTIFKICQVLGTPKKTDWPEGYQLSSAMNFLWP 239
            DIW+VGC++ E+ +  RP     ++ D+ F+I   +G  +K   PE             
Sbjct: 545 ADIWSVGCVVVEMASGKRPW----AQFDSNFQIMFKVGMGEKPQAPE------------- 673

Query: 240 QCIPNNLKTLIPNASSEAIQLLRDLLQWDPKKRPTASQALRYPYFQIG 287
                       + S E    +   LQ DPK+R +A + L   + + G
Sbjct: 674 ------------SLSQEGHDFIDHCLQHDPKQRLSAIELLEQNFCKSG 781
>00300
          Length = 2318

 Score = 99.0 bits (245), Expect = 5e-21,   Method: Compositional matrix adjust.
 Identities = 73/292 (25%), Positives = 129/292 (44%), Gaps = 8/292 (2%)
 Frame = -1

Query: 3    RYTTIKQLGDGTYGSVLLGRSIESGELIAIKKMKRKFYSWEECMNL-REVKSLKKLNHAN 61
            R+    ++G+G +G V    ++ +GEL+A+K+MK +    ++   +  E+K  + + H N
Sbjct: 1655 RWQRGNKIGEGQFGKVYTAVNMSTGELMALKEMKFQPNDLQQLREMCDEIKIFEGIQHEN 1476

Query: 62   IVKLKEVIRENDHLYFIFEYMKENLYQLIKERNKL-FPESAIRNIMYQILQGLAFIHKHG 120
            +VK   V    D +    EY        I+E  K+  PE  IR    +I+  +  +H++ 
Sbjct: 1475 LVKYYGVEVHKDEMLMFMEYCDTGT---IEEAAKMGLPEYLIRRYTREIVLAVNHLHENS 1305

Query: 121  FFHRDLKPENLLCMGPELVKIADFGLAREIRSRPP----YTDYVSTRWYRAPEVLLRST- 175
              HRD+K  N+       VK+ DFG + +++S       + + V T  Y APEV  ++  
Sbjct: 1304 IVHRDIKGANIFLTSNGHVKLGDFGCSVKLKSHTTMPGEFHNLVGTTAYMAPEVFTQNDQ 1125

Query: 176  -NYSSPIDIWAVGCIMAEVYTLRPLFPGASEIDTIFKICQVLGTPKKTDWPEGYQLSSAM 234
              Y    DIW++GC++ E+ T                     G     D    YQ+   +
Sbjct: 1124 GGYGRAADIWSLGCVVIEMAT---------------------GKRPWHDLDNNYQIMYKV 1008

Query: 235  NFLWPQCIPNNLKTLIPNASSEAIQLLRDLLQWDPKKRPTASQALRYPYFQI 286
                   +P++L       S E    L  ++  DP +R  ASQ L + + ++
Sbjct: 1007 GIGHKPAVPDSL-------SVEGKHFLDLIMCHDPAQRALASQLLDHTFTKV 873
>06405
          Length = 1965

 Score = 96.7 bits (239), Expect = 3e-20,   Method: Compositional matrix adjust.
 Identities = 76/275 (27%), Positives = 125/275 (45%), Gaps = 9/275 (3%)
 Frame = +1

Query: 9   QLGDGTYGSVLLGRSIESGELIAIKKMKRKFYSWEECMNLREVKSLKKLNHANIVKLKEV 68
           +LG G YG V         +++A+K +K    +  +   L E   +K++ H N+V+L  V
Sbjct: 280 RLGGGQYGDVYEAMWKRYNKIVAVKTLKEDTMALNDF--LEEAAIMKEMKHPNLVQLLGV 453

Query: 69  IRENDHLYFIFEYMKE-NLYQLIKERNKLFPESAIRNIMY---QILQGLAFIHKHGFFHR 124
                  Y + E+M   NL   +  R+    E+    +MY   QI  G+A++    F HR
Sbjct: 454 CTREPPFYIVTEFMPHGNLLDYL--RSSTREENGPTALMYMATQIASGMAYLETKNFIHR 627

Query: 125 DLKPENLLCMGPELVKIADFGLAREIRSRPPYTDYVSTRW---YRAPEVLLRSTNYSSPI 181
           DL   N L     +VK+ADFGLAR ++    YT ++  ++   + APE L  +  +S+  
Sbjct: 628 DLAARNCLVADSNMVKVADFGLARLMKDD-TYTAHIGAKFPIKWTAPEGLAFN-RFSTRS 801

Query: 182 DIWAVGCIMAEV--YTLRPLFPGASEIDTIFKICQVLGTPKKTDWPEGYQLSSAMNFLWP 239
           DIWA G ++ E+  Y + P +PG  E+  ++ + +            GY++         
Sbjct: 802 DIWAFGVLLWELATYGMSP-YPGV-ELTEVYHLLE-----------RGYRMERP------ 924

Query: 240 QCIPNNLKTLIPNASSEAIQLLRDLLQWDPKKRPT 274
                      P   ++   L+    QWDPK RPT
Sbjct: 925 -----------PGTPADVYILMLKCWQWDPKDRPT 996
>12721
          Length = 821

 Score = 91.3 bits (225), Expect = 1e-18,   Method: Compositional matrix adjust.
 Identities = 57/193 (29%), Positives = 98/193 (50%), Gaps = 1/193 (0%)
 Frame = +1

Query: 9   QLGDGTYGSVLLGRSIESGELIAIKKMKRKFYSWEECMNLREVKSLKKLNHANIVKLKEV 68
           ++G+G+ G V +  S   G  +A+KKM  +     E +   EV  ++  +H NIV++   
Sbjct: 109 KIGEGSTGIVCIATS-RDGRQMAVKKMDLRKQQRRELL-FNEVVVMRDYHHPNIVEMYNS 282

Query: 69  IRENDHLYFIFEYMKENLYQLIKERNKLFPESAIRNIMYQILQGLAFIHKHGFFHRDLKP 128
              ND L+ + E+M+      I   N++  E  I  +    L+ LAF+H +G  HRD+K 
Sbjct: 283 YLVNDELWVVMEFMEGGALTDIVTNNRM-DEVQIATVCRACLKALAFLHANGVIHRDIKS 459

Query: 129 ENLLCMGPELVKIADFGLAREI-RSRPPYTDYVSTRWYRAPEVLLRSTNYSSPIDIWAVG 187
           +++L      VK+ DFG   ++ +        V T ++ APEV+ R   Y   +DIW++G
Sbjct: 460 DSILLSHDGKVKLXDFGFCAQVTQDLQKRKSLVGTPYWMAPEVISR-LPYGPEVDIWSLG 636

Query: 188 CIMAEVYTLRPLF 200
            ++ E+    P F
Sbjct: 637 IMVMEMIDAEPPF 675
>28638
          Length = 1458

 Score = 67.4 bits (163), Expect(2) = 8e-18,   Method: Compositional matrix adjust.
 Identities = 38/100 (38%), Positives = 57/100 (57%), Gaps = 4/100 (4%)
 Frame = -1

Query: 103 RNIMYQILQGLAFIH--KHGFFHRDLKPENLLCMGPE--LVKIADFGLAREIRSRPPYTD 158
           R    Q+   L F+   +    H DLKPEN+L   P+   +KI DFG + ++  R     
Sbjct: 828 RKFAQQLCTALLFLATPEMNIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQR--IYQ 655

Query: 159 YVSTRWYRAPEVLLRSTNYSSPIDIWAVGCIMAEVYTLRP 198
           Y+ +R+YR+PEVLL    Y   ID+W++GCI+ E++T  P
Sbjct: 654 YIQSRFYRSPEVLL-GVPYDLAIDMWSLGCILVEMHTGEP 538

 Score = 41.2 bits (95), Expect(2) = 8e-18,   Method: Compositional matrix adjust.
 Identities = 31/102 (30%), Positives = 50/102 (49%), Gaps = 8/102 (7%)
 Frame = -3

Query: 1    MNRYTTIKQLGDGTYGSVLLGRSIESGELIAIKKMKRK--FYSWEECMNLREVKSLKKLN 58
            ++RY     +G G++G V+        E +AIK +K K  F +  +     EVK L+ +N
Sbjct: 1150 LDRYEIDSLIGKGSFGQVVKAYDHGDQEQVAIKIIKNKKPFLNQAQI----EVKLLELMN 983

Query: 59   HAN------IVKLKEVIRENDHLYFIFEYMKENLYQLIKERN 94
              +      IV+LK      +HL  +FE +  NLY L++  N
Sbjct: 982  RHDADNXYYIVRLKRHFMFRNHLCLVFELLSYNLYDLLRNTN 857

 Score = 36.6 bits (83), Expect = 0.030,   Method: Compositional matrix adjust.
 Identities = 28/97 (28%), Positives = 38/97 (39%), Gaps = 5/97 (5%)
 Frame = -2

Query: 128 PENLLCMGPELVKIADFGLAREIRSRPPYTDYVSTRWYRAPEVLLRSTNYSSPIDIWAVG 187
           P    C+ P +V+      A  +     YT        RA     R      P+  W + 
Sbjct: 746 PRTFCCVTPSVVQSKSSTSAALVSWDKGYTSTS-----RAGSTGRRRCYXXCPM-TWPLT 585

Query: 188 CIMAEVYTLR-----PLFPGASEIDTIFKICQVLGTP 219
           C    VY  R     PLF G++E D + KI +VLG P
Sbjct: 584 CGXWAVYWWRCTXGNPLFAGSNEFDQMMKIVEVLGVP 474
>18921
          Length = 697

 Score = 87.4 bits (215), Expect = 1e-17,   Method: Compositional matrix adjust.
 Identities = 56/199 (28%), Positives = 103/199 (51%), Gaps = 2/199 (1%)
 Frame = +2

Query: 2   NRYTTIKQLGDGTYGSVLLGRSIESGELIAIKKMKRKFYSWEECMNLREVKSLKKLNHAN 61
           + +  + +LG+G+YGSV      E+G+++AIK++       E    ++E+  +++ +   
Sbjct: 29  DVFDILGKLGEGSYGSVFKSLHKETGQVLAIKQVPVDTDLQE---IIKEISIMQQCDSKY 199

Query: 62  IVKLKEVIRENDHLYFIFEYMKE-NLYQLIKERNKLFPESAIRNIMYQILQGLAFIHKHG 120
           IVK      +N  L+ + EY    ++  +++ RNK   E  I  I+Y  L+GL ++H   
Sbjct: 200 IVKYYGSYFKNTDLWIVMEYCGAGSVSDIMRLRNKTLVEREIATILYYTLKGLXYLHSRR 379

Query: 121 FFHRDLKPENLLCMGPELVKIADFGLAREIR-SRPPYTDYVSTRWYRAPEVLLRSTNYSS 179
             HRD+K  N+L       K+ADFG+A ++  +       + T ++ APEV ++   Y  
Sbjct: 380 KIHRDIKAGNILLNNEGHAKLADFGVAGQLTDTMAKRNTVIGTPYWMAPEV-IQEIGYDC 556

Query: 180 PIDIWAVGCIMAEVYTLRP 198
             DIW++G    E+   +P
Sbjct: 557 VADIWSLGITALEMAEGKP 613
>15910
          Length = 1361

 Score = 85.9 bits (211), Expect = 4e-17,   Method: Compositional matrix adjust.
 Identities = 70/203 (34%), Positives = 98/203 (48%), Gaps = 3/203 (1%)
 Frame = +2

Query: 86  LYQLIKERNKLFPESAIRNIMYQILQGLAFIHKHGFFHRDLKPENLL--CMGPEL-VKIA 142
           L+  I  R +   + A R I   IL G+ +IH +G  HRDLKPENLL  CM  +  +K+A
Sbjct: 425 LFDRIVTRGQYTEKDAARAIS-DILHGVQYIHANGVVHRDLKPENLLYECMTDDSKLKLA 601

Query: 143 DFGLAREIRSRPPYTDYVSTRWYRAPEVLLRSTNYSSPIDIWAVGCIMAEVYTLRPLFPG 202
           DFGL+R I      +    T  Y APEV L+   Y+  +D+W+VG I   +      F  
Sbjct: 602 DFGLSRIIEPEVQMSTVCGTPGYCAPEV-LKGDKYTPSVDMWSVGVIAYILLCGYEPFFA 778

Query: 203 ASEIDTIFKICQVLGTPKKTDWPEGYQLSSAMNFLWPQCIPNNLKTLIPNASSEAIQLLR 262
            +E +   KI +  G  K   + E Y         W +             S  A  ++R
Sbjct: 779 ENEFEMYRKIIK--GEYK---FDEEY---------WSE------------ISENAKDVVR 880

Query: 263 DLLQWDPKKRPTASQALRYPYFQ 285
            LL  DPKKR TA++ALR P+ +
Sbjct: 881 KLLVIDPKKRLTATEALRLPWVK 949
>21808
          Length = 1011

 Score = 83.6 bits (205), Expect = 2e-16,   Method: Compositional matrix adjust.
 Identities = 51/170 (30%), Positives = 89/170 (52%), Gaps = 5/170 (2%)
 Frame = +1

Query: 48  LREVKSLKKLNHANIVKLKEVIRENDHLYFIFEYMKE-NLYQLIKERNKLFPESAIRNIM 106
           L E + +KKL H  +++L  V  ++D ++ I E MK  +L + ++ + ++    A+ +I 
Sbjct: 76  LAEAQIMKKLRHPKLIQLYAVCTQDDPIFIITELMKNGSLLEFLQGKGRVLKLPALIDIG 255

Query: 107 YQILQGLAFIHKHGFFHRDLKPENLLCMGPELVKIADFGLAREIRSRPPYTDYVSTRW-- 164
            QI  G+A++    + HRDL   N+L      VKIADFGLAR I+    Y   V  R+  
Sbjct: 256 AQIACGMAYLESQNYIHRDLAARNILVSDNNTVKIADFGLARVIKE-DEYEARVGARFPI 432

Query: 165 -YRAPEVLLRSTNYSSPIDIWAVGCIMAEVYTL-RPLFPGASEIDTIFKI 212
            + APE       ++   D+W+ G ++ E  T  R  +PG +  + + ++
Sbjct: 433 KWTAPEA-ANYNRFTIKSDVWSFGILLTETVTYGRVPYPGMTNAEVLHQV 579
>03240
          Length = 1683

 Score = 82.8 bits (203), Expect = 4e-16,   Method: Compositional matrix adjust.
 Identities = 64/256 (25%), Positives = 112/256 (43%), Gaps = 47/256 (18%)
 Frame = -3

Query: 4    YTTIKQLGDGTYGSVLLGRSIESGELIAIKKMKR-KFYSWEECMNLR-EVKSLKKLNHAN 61
            +  IK LG G +G V L R  ++G L A+K +++       +  +++ E   L + ++  
Sbjct: 1285 FEKIKTLGVGAFGEVSLCRKNDTGMLYAMKTLRKSDVLKRNQVAHVKAERDILAEADNEW 1106

Query: 62   IVKLKEVIRENDHLYFIFEYMKENLYQLIKERNKLFPESAIRNIMYQILQGLAFIHKHGF 121
            +VKL    +++++LYF+ +Y+       +  R ++  E   R  + +++Q +  +H+ GF
Sbjct: 1105 VVKLYYSFQDHNYLYFVMDYVPGGDLMGLLIRMEILDEPLARFYVAELVQAIESVHRMGF 926

Query: 122  FHRDLKPENLLCMGPELVKIADFGLA---------------------------------- 147
             HRD+KP+N+L      +K+ DFGL                                   
Sbjct: 925  IHRDIKPDNILIDRNGHIKLTDFGLCTGFRWTHNSKYYQRDGTHARQDSMEVKCQLDEQC 746

Query: 148  -----------REIRSRPPYTDYVSTRWYRAPEVLLRSTNYSSPIDIWAVGCIMAEVYTL 196
                       R+   R      V T  Y APEVL R   Y+S  D W+VG I+ E+   
Sbjct: 745  QCEILKPLERRRKREQRCLAHSLVGTPNYIAPEVLSRLGGYTSVCDWWSVGVILFEMLVG 566

Query: 197  RPLFPGASEIDTIFKI 212
             P F   +  +T +K+
Sbjct: 565  HPPFYANTPAETQYKV 518
>09606
          Length = 1300

 Score = 79.0 bits (193), Expect = 5e-15,   Method: Compositional matrix adjust.
 Identities = 78/314 (24%), Positives = 132/314 (42%), Gaps = 27/314 (8%)
 Frame = -3

Query: 1    MNRYTTIKQLGDGTYGSVLLGRSIESGELIAI---KKMKRKFYSWEECMNLREVKSLKKL 57
            M  +   ++LG G +  +  GR   +   +AI   +K KR      E  N   V+    +
Sbjct: 1118 MENFVLYEELGKGEHSIIYKGRRKGTINFVAIHCIEKCKRP-----EVTN--TVRMTHDI 960

Query: 58   NHANIVKLKEVIRENDHLYFIFEYMKENLYQLIKERNKLFPESAIRNIMYQILQGLAFIH 117
            +H N+V+  E    ++HL+ + E         I  ++   PE++IR+    ++ GL +IH
Sbjct: 959  SHPNVVQFHEWYETSNHLWLVVELCTGGSLADILAQDHHLPETSIRDFGIHLVTGLHYIH 780

Query: 118  KHGFFHRDLKPENLLCMGPELVKIADFGLAR--------------------EIRSRPPYT 157
              G    DL+P  +L     ++K ADFGL++                     I+S     
Sbjct: 779  SLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEAGDQWNIQSAEEMM 600

Query: 158  DYVSTRW---YRAPEVLLRSTNYSSPIDIWAVGCIMAEVYTLRPLFPGASEIDTIFKIC- 213
              V T     Y APEV  +    S   D+WA+GC+  E+++  P F G +   T  K+  
Sbjct: 599  KQVPTSGSPTYMAPEV-FQGAEPSIMSDLWALGCVFYEMFSGHPPFLGETYDITKDKVLN 423

Query: 214  QVLGTPKKTDWPEGYQLSSAMNFLWPQCIPNNLKTLIPNASSEAIQLLRDLLQWDPKKRP 273
            +    PK     +G +LS+                     S E + LL  LLQ D  +R 
Sbjct: 422  KEFPLPK----VKGSRLSA-------------------KPSPEFLNLLESLLQKDSTRRL 312

Query: 274  TASQALRYPYFQIG 287
            + +  +++ ++Q G
Sbjct: 311  SWASLVKHAFWQGG 270
>19301
          Length = 712

 Score = 77.8 bits (190), Expect = 1e-14,   Method: Compositional matrix adjust.
 Identities = 46/142 (32%), Positives = 77/142 (54%), Gaps = 1/142 (0%)
 Frame = +2

Query: 5   TTIKQLGDGTYGSVLLGRSIESGELIAIKKMKRKFYSWEECMNLREVKSLKKLNHANIVK 64
           T ++ LG G  G+V LG+     E +A+KK++         +   ++++L+KLNH NI+ 
Sbjct: 314 TDLEWLGSGAQGAVFLGKL--CAEEVAVKKVRD--------IKETDIRNLRKLNHPNIIS 463

Query: 65  LKEVIRENDHLYFIFEYM-KENLYQLIKERNKLFPESAIRNIMYQILQGLAFIHKHGFFH 123
            K V  +      I EY     LY+++++  K  P + + +   QI  G+ ++H H   H
Sbjct: 464 FKGVCTQAPCYCIIMEYCPYGQLYEVLRD-GKEIPPALVLDWSKQIASGMNYLHSHKIIH 640

Query: 124 RDLKPENLLCMGPELVKIADFG 145
           RDLK  N+L    ++VKI+DFG
Sbjct: 641 RDLKSPNVLVAKNDVVKISDFG 706
>03294
          Length = 1684

 Score = 76.3 bits (186), Expect = 4e-14,   Method: Compositional matrix adjust.
 Identities = 36/105 (34%), Positives = 62/105 (59%)
 Frame = -1

Query: 180  PIDIWAVGCIMAEVYTLRPLFPGASEIDTIFKICQVLGTPKKTDWPEGYQLSSAMNFLWP 239
            P+D+W++G I A++    P+F G SEID +FKI +++GTP +  WPE ++L  A N ++P
Sbjct: 1675 PVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIFRIIGTPTEQTWPEFHKL-PAFNGMFP 1499

Query: 240  QCIPNNLKTLIPNASSEAIQLLRDLLQWDPKKRPTASQALRYPYF 284
                  L   + +  S  + L+   L+ DP +R +  + L++ YF
Sbjct: 1498 LWKEGKLSETLTDLDSLGLDLIERTLKCDPAQRISCKKMLQHAYF 1364
>01718
          Length = 959

 Score = 75.1 bits (183), Expect = 7e-14,   Method: Compositional matrix adjust.
 Identities = 76/285 (26%), Positives = 126/285 (44%), Gaps = 11/285 (3%)
 Frame = +3

Query: 8   KQLGDGTYGSVLLGRSIESGELIAIKKMKRKFYSWEECMNLREVKSLKKLNHANIVKLKE 67
           +++G G +  V       +G+++A+K       S    M LREV+ L +L HANI++   
Sbjct: 165 EKIGAGFFSEVFKVTHRITGQVMALKM--NTMTSNRHNM-LREVQLLNRLQHANILRFMG 335

Query: 68  VIRENDHLYFIFEYM-KENLYQLIKERNKLFPESAIRNIMYQILQGLAFIHKHGFFHRDL 126
           V      L+ + EY+   NL QL++++++  P +    +   + +GL ++H   F HRDL
Sbjct: 336 VCVHEGQLHALTEYIPSGNLEQLLEKKDEELPWTQRIQLTLGLARGLDYLHSTRFIHRDL 515

Query: 127 KPENLLC-----MGPELVKIADFGLAREI-----RSRPPYTDYVSTRWYRAPEVLLRSTN 176
             +N+L       G   V IADFGLA +I     + + P    V + ++ APEV L    
Sbjct: 516 TSKNILIRREDNHGYHAV-IADFGLATKIPDPLDKEKLP---TVGSPYWMAPEV-LNGHF 680

Query: 177 YSSPIDIWAVGCIMAEVYTLRPLFPGASEIDTIFKICQVLGTPKKTDWPEGYQLSSAMNF 236
           Y+   D+++VG IM E+    P  P                 P+  ++   Y   S M  
Sbjct: 681 YNERADLFSVGIIMCEITARIPADPDI--------------MPRMNNFGVDYVALSEM-- 812

Query: 237 LWPQCIPNNLKTLIPNASSEAIQLLRDLLQWDPKKRPTASQALRY 281
                        I     + +QL     Q DP+KRP   + + +
Sbjct: 813 -------------ISYCPLDYLQLAFKCCQVDPQKRPRGVEIIEW 908
>17975
          Length = 449

 Score = 73.9 bits (180), Expect = 2e-13,   Method: Composition-based stats.
 Identities = 45/136 (33%), Positives = 70/136 (51%), Gaps = 3/136 (2%)
 Frame = +3

Query: 15  YGSVLLGRSIESGELIAIKKM-KRKFYSWEECMNLREVKSLKKLNHANIVKLKEVIREND 73
           +  V L R + +GE +A+K + K K          +EV+ +K + H N+V+L EVI    
Sbjct: 6   FAVVKLARHVFTGEKVAVKVIDKTKLDEVSRSHLFQEVRCMKLVQHPNVVRLYEVIDTQT 185

Query: 74  HLYFIFEYMKE-NLYQLIKERNKLFPESAIRNIMYQILQGLAFIHKHGFFHRDLKPENLL 132
            LY I E     ++Y  I   +    E   +    QI++ +++ HK    HRDLKPEN++
Sbjct: 186 KLYLILELGDGGDMYDYIMRHSGGLEEKLAKRYFRQIVEAISYCHKLHVVHRDLKPENVV 365

Query: 133 CM-GPELVKIADFGLA 147
               P LVK+ DFG +
Sbjct: 366 FFEKPGLVKLTDFGFS 413
>23319
          Length = 2235

 Score = 72.8 bits (177), Expect = 3e-13,   Method: Compositional matrix adjust.
 Identities = 43/115 (37%), Positives = 65/115 (56%), Gaps = 1/115 (0%)
 Frame = +3

Query: 177 YSSPIDIWAVGCIMAEVYTL-RPLFPGASEIDTIFKICQVLGTPKKTDWPEGYQLSSAMN 235
           YS+ ID+W+ GCI AE+    RPLFPG  + D + +I ++LGTP +  WP   QL +   
Sbjct: 27  YSTSIDMWSAGCIFAELANAGRPLFPGNDDDDQLKRIFKLLGTPTEDQWPGMTQLPNYRM 206

Query: 236 FLWPQCIPNNLKTLIPNASSEAIQLLRDLLQWDPKKRPTASQALRYPYFQIGHPL 290
           F     +    + ++P  +S+   LL+ LL   P  R +A +AL++PYF    PL
Sbjct: 207 FPMYH-VTTTWQQVVPKLNSKGRDLLQCLLVCCPSDRMSADEALQHPYFADLPPL 368
>03508
          Length = 1463

 Score = 72.8 bits (177), Expect = 4e-13,   Method: Compositional matrix adjust.
 Identities = 38/127 (29%), Positives = 70/127 (55%), Gaps = 2/127 (1%)
 Frame = +1

Query: 77  FIFEYMKENLYQLIKERNKLFPESAIRNIMYQILQGLAFIHKHGFFHRDLKPENLLC-MG 135
            IFE++    +   K+  + F +  IR  +Y++++ L F H  G  HRD+KP N++    
Sbjct: 811 LIFEHVNNTDF---KQLYQTFTDYDIRFYLYELMKALDFCHSMGIMHRDVKPHNVMIDHE 981

Query: 136 PELVKIADFGLAREIRSRPPYTDYVSTRWYRAPEVLLRSTNYSSPIDIWAVGCIMAE-VY 194
            + +++ D+GLA        Y   V++R+++ PE+LL    Y   +D+W++GC+ A  ++
Sbjct: 982 NKKLRLIDWGLAEFYHPGMEYNVRVASRYFKGPELLLDYQMYDYSLDMWSLGCMFASMIF 1161

Query: 195 TLRPLFP 201
              PL P
Sbjct: 1162RKEPLLP 1182

 Score = 48.5 bits (114), Expect = 8e-06,   Method: Compositional matrix adjust.
 Identities = 34/112 (30%), Positives = 52/112 (46%), Gaps = 10/112 (8%)
 Frame = +2

Query: 183  IWAVGCIMAEVYTLRPLFPGASEIDTIFKICQVLGTPKKTDWPEGYQLSSAMNF------ 236
            +WA  C+ A      P F G    D + +I +VLGT     + E YQ+     F      
Sbjct: 1130 VWA-ACLPA*SSGKSPFFHGHDNYDQLVRIAKVLGTDDLYGYIEKYQIDLDPRFNDILGR 1306

Query: 237  ----LWPQCIPNNLKTLIPNASSEAIQLLRDLLQWDPKKRPTASQALRYPYF 284
                 W + + +  + LI   S EA+  L  LL++D  +R TA +A+ +PYF
Sbjct: 1307 HSRKRWERFVHSENQHLI---SPEALDFLDKLLRYDHNERLTAREAMDHPYF 1453
>19761
          Length = 473

 Score = 69.3 bits (168), Expect = 5e-12,   Method: Compositional matrix adjust.
 Identities = 41/127 (32%), Positives = 66/127 (51%), Gaps = 3/127 (2%)
 Frame = -3

Query: 97  FPESAIRNIMYQILQGLAFIHKHG--FFHRDLKPENLLCMGPELVKIADFGLAREIRSRP 154
            PE  I   + Q    L ++H H     HRDLKP+N+       V++ D GLAR++    
Sbjct: 432 LPERLIVCWLMQTASALNYMHTHTPVILHRDLKPQNIYVTEKGDVRLGDLGLARKLTGPA 253

Query: 155 PY-TDYVSTRWYRAPEVLLRSTNYSSPIDIWAVGCIMAEVYTLRPLFPGASEIDTIFKIC 213
            + T  V T  Y +PE+L +   Y+S  DIW++GC+  ++   +    G+ E+  +F + 
Sbjct: 252 DFATSQVGTIMYLSPEILSQQP-YNSKSDIWSLGCVFYDITGKK----GSDEMGVMFLLV 88

Query: 214 QVLGTPK 220
           QV+G  K
Sbjct: 87  QVMGGRK 67
>09007
          Length = 1440

 Score = 67.4 bits (163), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 54/202 (26%), Positives = 94/202 (46%), Gaps = 14/202 (6%)
 Frame = -1

Query: 8   KQLGDGTYGSVLLGR-SIESGE--LIAIKKMKRKFYSWEECMNLREVKSLKKLNHANIVK 64
           K LG G +G+V     + ESGE   +A+K + +     +    L+E   ++ L+H NIV+
Sbjct: 861 KSLGQGHFGTVRQAIWTAESGEKVQVAVKCLSKDKIHKDGQEFLKETAIMQMLDHENIVR 682

Query: 65  LKEVIRENDHLYFIFEYMK--ENLYQLIKERNKLFPESAIR--NIMYQILQGLAFIHKHG 120
           +  V+ +N     +   +    +L + +KE +     S  R  +   Q+  G++++    
Sbjct: 681 VYGVVMDNGADIMLVTELAPMRSLLECVKEVSARVDFSVPRLCDFSQQVCDGMSYLESKR 502

Query: 121 FFHRDLKPENLLCMGPELVKIADFGLAREIRSRPPYTDYVST-------RWYRAPEVLLR 173
             HRDL   N+L      VKI+D G++  + +   Y     T        W  APE   R
Sbjct: 501 LVHRDLAARNILLFSKSKVKISDVGVSGALGAGKEYYQSQQTIHLQNAVAWC-APES-FR 328

Query: 174 STNYSSPIDIWAVGCIMAEVYT 195
           +  +SS  D+WA G ++ E +T
Sbjct: 327 NLCFSSASDVWAFGVLLWEFFT 262
>32359
          Length = 928

 Score = 62.4 bits (150), Expect(2) = 2e-11,   Method: Compositional matrix adjust.
 Identities = 40/125 (32%), Positives = 70/125 (56%), Gaps = 11/125 (8%)
 Frame = -1

Query: 4   YTTIKQLGDGTYGSVLLGRSIESGELIAIKKM--KRKFYSWEECMNLREVKSLKKLNHAN 61
           YT  K +G+G++G V   + +++ EL+AIKK+   ++F +       RE++ ++KL H N
Sbjct: 424 YTDAKVIGNGSFGVVYQAKLVDTSELVAIKKVLQDKRFKN-------RELQIMRKLEHQN 266

Query: 62  IVKLKEVI------RENDHLYFIFEYMKENLYQLIKERNK---LFPESAIRNIMYQILQG 112
           IVKLK         ++   L  + EY+ E +Y++ +  +K     P   I+  MYQ+ + 
Sbjct: 265 IVKLKFFFYSSGEKKDEVFLNLVLEYVPETVYRVARHYSKSKQTIPILYIKLYMYQLFRS 86

Query: 113 LAFIH 117
           LA+IH
Sbjct: 85  LAYIH 71

 Score = 25.0 bits (53), Expect(2) = 2e-11,   Method: Compositional matrix adjust.
 Identities = 11/18 (61%), Positives = 14/18 (77%)
 Frame = -3

Query: 120 GFFHRDLKPENLLCMGPE 137
           G  HRD+KP+NLL + PE
Sbjct: 65  GVCHRDIKPQNLL-LDPE 15
>01392
          Length = 1806

 Score = 67.0 bits (162), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 57/196 (29%), Positives = 83/196 (42%), Gaps = 16/196 (8%)
 Frame = -1

Query: 105  IMYQILQGLAFIHKHGFFHRDLKPENLLCMGPEL---VKIADFGLAREIRS------RPP 155
            ++  I + L F+H  G  HRDLKPEN+LC   +    VKI DF LA  I         P 
Sbjct: 1776 VVRHIARALDFLHSKGIAHRDLKPENILCEHLDDVVPVKICDFDLASGISCDGDGTKTPE 1597

Query: 156  YTDYVSTRWYRAPEVLLR----STNYSSPIDIWAVGCIMAEVYTLRPLFPGASEIDTIFK 211
                V +  Y APEV+      S +Y    D+W++G I+  +    P F G    D    
Sbjct: 1596 LLTPVGSAEYMAPEVVDAWVGDSFSYDKRCDLWSLGIILYIMLCGYPPFYGQCGED---- 1429

Query: 212  ICQVLGTPKKTDWPEGYQLSSAMNFLWPQCIPNNLK---TLIPNASSEAIQLLRDLLQWD 268
                        W  G       + L+      + K       + SS A  L+R LL  +
Sbjct: 1428 ----------CGWNRGEACHDCQDMLFNSIQDGHYKFPSQEWTSISSSAKDLIRHLLVRE 1279

Query: 269  PKKRPTASQALRYPYF 284
            P+KR +A+  L++P+ 
Sbjct: 1278 PRKRYSAADVLKHPWI 1231
>13212
          Length = 1067

 Score = 67.0 bits (162), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 52/209 (24%), Positives = 95/209 (45%), Gaps = 9/209 (4%)
 Frame = -1

Query: 86   LYQLIKERNKLFPESAIRNIMYQILQGLAFIHKHGFFHRDLKPENLLCMGPELVKIADFG 145
            L  ++ +  K   E+ I  + +++   L F+H+H   HRD+K  N+L      VK+ADFG
Sbjct: 1022 LDSIMVDLEKPMTEAQICYVCHEMCMALDFLHRHHVIHRDIKAGNVLLTIDGEVKLADFG 843

Query: 146  L-AREIRSRPPYTDYVSTRWYRAPEVL----LRSTNYSSPIDIWAVGCIMAEVYTLRPLF 200
            + A+  +++     ++ T ++ APEV+    L+ T Y    DIW++G  + E   + P  
Sbjct: 842  VSAKNTQTQQKRDTFIGTPYWMAPEVVLCETLKDTPYDFKADIWSLGVTLIEFAQIEPPN 663

Query: 201  PGASEIDTIFKICQ----VLGTPKKTDWPEGYQLSSAMNFLWPQCIPNNLKTLIPNASSE 256
                 +  + KI +     L  PKK  W + ++     +F+  +C+              
Sbjct: 662  KEMHPMRVLIKIHKSDPPTLEKPKK--WTKLFK-----DFI-AKCLVK------------ 543

Query: 257  AIQLLRDLLQWDPKKRPTASQALRYPYFQ 285
                       DP  RPTA++ L +P+ +
Sbjct: 542  -----------DPNLRPTAAELLEHPFMK 489
>14477
          Length = 493

 Score = 66.2 bits (160), Expect = 4e-11,   Method: Composition-based stats.
 Identities = 43/151 (28%), Positives = 78/151 (51%), Gaps = 3/151 (1%)
 Frame = -1

Query: 9   QLGDGTYGSVLLGR-SIESGEL-IAIKKMKRKFYSWE-ECMNLREVKSLKKLNHANIVKL 65
           +LG G +GSV+ G   ++  E+ +AIK +K        +   ++E + +KK++H +IV+L
Sbjct: 469 KLGAGNFGSVMKGVCRLDDREIPVAIKVLKNADLDPSVQSELIKEAEVMKKMDHMHIVRL 290

Query: 66  KEVIRENDHLYFIFEYMKENLYQLIKERNKLFPESAIRNIMYQILQGLAFIHKHGFFHRD 125
             +  E + +  + E  K         +NK  P   I  +M+Q+ QG+ ++  + F HRD
Sbjct: 289 IGLC-EGETMMLVLELAKLGPLNKFLPKNKHLPLWNILELMWQVSQGMEYLEANKFVHRD 113

Query: 126 LKPENLLCMGPELVKIADFGLAREIRSRPPY 156
           L   N+L       KI+DFG+++ +     Y
Sbjct: 112 LAARNILLCDEHFAKISDFGMSKTLSRENNY 20
>18287
          Length = 678

 Score = 66.2 bits (160), Expect = 4e-11,   Method: Compositional matrix adjust.
 Identities = 43/118 (36%), Positives = 63/118 (53%), Gaps = 6/118 (5%)
 Frame = -3

Query: 176 NYSSPIDIWAVGCIMAEVYTLRPLFPGASEIDTIFKICQVLGTPKKTDWPEGYQLSSAMN 235
           +Y   IDIW+VGCI AE+ + R LF     +  +  I  ++GTP+  D     +   A N
Sbjct: 676 HYDYSIDIWSVGCIFAELLSRRILFQAQGPVQQLDMIINLVGTPRPEDMERACE--GARN 503

Query: 236 FLWPQCIP---NNLKTLI---PNASSEAIQLLRDLLQWDPKKRPTASQALRYPYFQIG 287
            +  Q  P    NL TL    P+A+ EA++LL  +L  +PK R +A +AL +PY   G
Sbjct: 502 HILNQ--PFRRQNLLTLYNLSPHATHEAVRLLTRMLILNPKNRISAEEALSHPYLDEG 335
>30755
          Length = 1137

 Score = 65.5 bits (158), Expect = 6e-11,   Method: Compositional matrix adjust.
 Identities = 37/104 (35%), Positives = 52/104 (50%), Gaps = 1/104 (0%)
 Frame = +2

Query: 95  KLFPESAIRNIMYQILQGLAFIHKHGFFHRDLKPENLLCMGPELVKIADFGLARE-IRSR 153
           ++F E   R    +I+  L ++H  G  +RDLK ENLL      +K+ADFGL +E I   
Sbjct: 17  RIFTEERTRFYGAEIISALGYLHSQGIIYRDLKLENLLLDKDGHIKVADFGLCKEDITYG 196

Query: 154 PPYTDYVSTRWYRAPEVLLRSTNYSSPIDIWAVGCIMAEVYTLR 197
                +  T  Y APEV L   +Y   +D W  G +M E+   R
Sbjct: 197 RTTKTFCGTPEYLAPEV-LDDNDYGRAVDWWGTGVVMYEMICGR 325
>27405
          Length = 532

 Score = 64.7 bits (156), Expect = 1e-10,   Method: Composition-based stats.
 Identities = 48/174 (27%), Positives = 81/174 (46%), Gaps = 6/174 (3%)
 Frame = -3

Query: 15  YGSVLLGRSIESGELIAIKKMKRKFYSWEE----CMNLREVKSLKKLNHAN--IVKLKEV 68
           +G V   R  ++G++ A+K + +K    +      +N R + SL      +  IV +   
Sbjct: 527 FGEVYGCRKADTGKMYAMKCLDKKRIKMKGGETLALNERIMLSLVSTGEGSPFIVCMTYA 348

Query: 69  IRENDHLYFIFEYMKENLYQLIKERNKLFPESAIRNIMYQILQGLAFIHKHGFFHRDLKP 128
            +  + L FI + M          ++ +F E  +R    +++ GL  +H     +RDLKP
Sbjct: 347 FQTPEKLCFILDLMNGGDLHYHLSQHGVFTEKEVRFYAAEVMLGLEHMHSRFVVYRDLKP 168

Query: 129 ENLLCMGPELVKIADFGLAREIRSRPPYTDYVSTRWYRAPEVLLRSTNYSSPID 182
            N+L      V+I+D GLA +   + P+   V T  Y APEVL++   Y S  D
Sbjct: 167 ANILLDENGHVRISDLGLACDFSKKKPHAS-VGTHGYMAPEVLMKGQAYDSSAD 9
>26560
          Length = 398

 Score = 64.7 bits (156), Expect = 1e-10,   Method: Composition-based stats.
 Identities = 33/98 (33%), Positives = 55/98 (56%)
 Frame = -1

Query: 93  RNKLFPESAIRNIMYQILQGLAFIHKHGFFHRDLKPENLLCMGPELVKIADFGLAREIRS 152
           ++ +F E  +R    +++ GL  +H     +RDLKP N+L      V+I+D GLA +   
Sbjct: 377 QHGVFTEKEVRFYAAEVMLGLEHMHSRFVVYRDLKPANILLDENGHVRISDLGLACDFSK 198

Query: 153 RPPYTDYVSTRWYRAPEVLLRSTNYSSPIDIWAVGCIM 190
           + P+   V T  Y APEVL++  +Y S  D ++ GC++
Sbjct: 197 KRPHAS-VGTHGYMAPEVLMKGQSYDSSADWFSFGCML 87
>18484
          Length = 635

 Score = 64.7 bits (156), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 43/127 (33%), Positives = 65/127 (51%), Gaps = 1/127 (0%)
 Frame = +1

Query: 85  NLYQLIKERNKLFPESAIRNIMYQILQGLAFIHKHGFFHRDLKPENLLCMGPELVKIADF 144
           +L   I++  K F E        +I  GL F+H  G  +RDLK +N++      +KIADF
Sbjct: 1   DLMYRIQQEGK-FKEPVAAFYAAEIAVGLFFLHDQGIIYRDLKLDNVMLDSEGHIKIADF 177

Query: 145 GLAREIRSRPPYT-DYVSTRWYRAPEVLLRSTNYSSPIDIWAVGCIMAEVYTLRPLFPGA 203
           G+ +E  +    T  +  T  Y APE++L    YS  +D WA G ++ E+   +P F G 
Sbjct: 178 GMCKEGMTGDATTRTFCGTPDYIAPEIVLYQP-YSKSVDWWAYGVLLFEMLAGQPPFDGE 354

Query: 204 SEIDTIF 210
            E D +F
Sbjct: 355 DE-DELF 372
>00392
          Length = 668

 Score = 64.3 bits (155), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 49/170 (28%), Positives = 81/170 (47%), Gaps = 8/170 (4%)
 Frame = +3

Query: 50  EVKSLKKLNHANIVKLKEVIRENDH-----LYFIFEYMKENLYQLIKERNKLFPESAIRN 104
           E + LK+L H NIV+  +   E++H     +  + E M     +   +R K      ++N
Sbjct: 81  EAEMLKELQHPNIVRFFDYWEEHNHRNRKVIILVTELMTSGTLKTYLKRFKKPNVKILKN 260

Query: 105 IMYQILQGLAFIHKHG--FFHRDLKPENLLCMGPE-LVKIADFGLAREIRSRPPYTDYVS 161
              Q+L+GL F+H       HRDLK +N+   GP   VKI D GLA  ++++      + 
Sbjct: 261 WCRQVLKGLYFLHTRTPPVIHRDLKCDNIFITGPTGSVKIGDLGLAT-LKNQSFAKSVIG 437

Query: 162 TRWYRAPEVLLRSTNYSSPIDIWAVGCIMAEVYTLRPLFPGASEIDTIFK 211
           T  + APE  +   +Y   +D++A G  M E+ +    +   S    I+K
Sbjct: 438 TPEFMAPE--MYEEHYDEAVDVYAFGMCMLEMASSEYPYSECSNAAQIYK 581
>27546
          Length = 426

 Score = 63.2 bits (152), Expect = 4e-10,   Method: Composition-based stats.
 Identities = 34/104 (32%), Positives = 58/104 (55%), Gaps = 1/104 (0%)
 Frame = -1

Query: 49  REVKSLKKLNHANIVKLKEVIRENDHLYFIFEYM-KENLYQLIKERNKLFPESAIRNIMY 107
           RE++ L +L+H NI+++  +++    ++    Y  K ++   IK+   +  E+  +   +
Sbjct: 333 RELEILTRLDHPNIIQIHSILQRGPKIFIFMRYAEKGDMLSHIKKTGPI-DEAQTKVWFF 157

Query: 108 QILQGLAFIHKHGFFHRDLKPENLLCMGPELVKIADFGLAREIR 151
           Q+ + L ++H H   HRDLK EN+L      VKIADFG AR  R
Sbjct: 156 QMAKALQYLHSHDIAHRDLKCENILLSKRLNVKIADFGFARYCR 25
>31489
          Length = 329

 Score = 62.4 bits (150), Expect = 5e-10,   Method: Compositional matrix adjust.
 Identities = 34/90 (37%), Positives = 53/90 (58%), Gaps = 6/90 (6%)
 Frame = +3

Query: 51  VKSLKKLNHANIVKLKEVIREND------HLYFIFEYMKENLYQLIKERNKLFPESAIRN 104
           +K LK   H NI+ ++E+++  D       ++ +F+ M+ +L+++I     L  E  IR 
Sbjct: 3   IKILKHFKHDNIISIREILKPKDSYHDFKDIHVVFDLMESDLHRIIYSDQPL-TEEHIRY 179

Query: 105 IMYQILQGLAFIHKHGFFHRDLKPENLLCM 134
            +YQIL+GL +IH     HRDLKP NLL M
Sbjct: 180 FLYQILRGLKYIHSANVVHRDLKPSNLLSM 269
>18401
          Length = 463

 Score = 62.4 bits (150), Expect = 5e-10,   Method: Compositional matrix adjust.
 Identities = 46/143 (32%), Positives = 69/143 (48%), Gaps = 18/143 (12%)
 Frame = -3

Query: 160 VSTRWYRAPEVLLRSTNYSSPIDIWAVGCIMAEVYTLRPLFPGASEIDTIFKICQVLGT- 218
           VSTR YRAPEV+L    +S P D+W+VGCIM E+YT   LF      + +  + ++LG+ 
Sbjct: 449 VSTRHYRAPEVIL-ELGWSHPCDVWSVGCIMFELYTGYTLFQTHDNKEHLAMMERILGSL 273

Query: 219 ----PKKT-----------DWPEGYQLSSAMNFLWPQCIP--NNLKTLIPNASSEAIQLL 261
                KKT           D PE    SS   ++     P    +K        +   L+
Sbjct: 272 PYRMAKKTKKQKYFHHGRLDVPER---SSMARYVRENTKPLLRYVKDRENKDHQQLFDLM 102

Query: 262 RDLLQWDPKKRPTASQALRYPYF 284
           + LL ++   R +  QAL++P+F
Sbjct: 101 KKLLAYEASSRYSLLQALQHPFF 33
>19094
          Length = 898

 Score = 62.4 bits (150), Expect = 5e-10,   Method: Compositional matrix adjust.
 Identities = 34/107 (31%), Positives = 56/107 (52%), Gaps = 1/107 (0%)
 Frame = +1

Query: 88  QLIKERNKLFPESAIRNIMYQILQGLAFIHKHGFFHRDLKPENLLCMGPELVKIADFGLA 147
            +++ RNK   E  I  I+Y  L+GL ++H     HRD+K  N+L       K+ADFG+A
Sbjct: 22  DIMRLRNKTLVEREIATILYYTLKGL*YLHSRRKIHRDIKAGNILLNNEGHAKLADFGVA 201

Query: 148 REIR-SRPPYTDYVSTRWYRAPEVLLRSTNYSSPIDIWAVGCIMAEV 193
            ++  +       + T ++ APEV ++   Y    DIW++G    E+
Sbjct: 202 GQLTDTMAKRNTVIGTPYWMAPEV-IQEIGYDCVADIWSLGITALEM 339
>14420
          Length = 528

 Score = 62.4 bits (150), Expect = 6e-10,   Method: Composition-based stats.
 Identities = 40/155 (25%), Positives = 77/155 (49%), Gaps = 2/155 (1%)
 Frame = +2

Query: 48  LREVKSLKKLNHANIVKLKEVIRENDHLYFIFEYMKE-NLYQLIKERNKLFPESAIRNIM 106
           + E+  +++  + NIV   +     + L+ + E++   +L  ++ E      E  I  + 
Sbjct: 44  INEILVMRENQNPNIVNYLDSYLVGEELWVVMEFLAGGSLTDVVTE--TCMDEGQIAAVC 217

Query: 107 YQILQGLAFIHKHGFFHRDLKPENLLCMGPELVKIADFGLAREIR-SRPPYTDYVSTRWY 165
            + LQ L F+H++   HRD+K +N+L      VK+ DFG   ++   +   +  V T ++
Sbjct: 218 RECLQALEFLHENQVIHRDIKSDNILLGMDGSVKLTDFGFCAQLSPEQSKRSTMVGTPYW 397

Query: 166 RAPEVLLRSTNYSSPIDIWAVGCIMAEVYTLRPLF 200
            APEV+ R   Y   +DIW++G +  E+    P +
Sbjct: 398 MAPEVVTRK-QYGPTVDIWSLGVMCIEMIEGEPPY 499
>14116
          Length = 1017

 Score = 59.7 bits (143), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 55/206 (26%), Positives = 97/206 (47%), Gaps = 15/206 (7%)
 Frame = -1

Query: 5   TTIKQLGDGTYGSV---LLGRSIESGE-LIAIKKMKRKFYSWEECMN-LREVKSLKKLNH 59
           T  +++G G +G V    L    + G+ L+A+K +        E  + L+E   +K  +H
Sbjct: 627 TMGEEIGKGNFGCVKRGFLTLPEQKGDILVAVKTLHNNNPREIELQSFLQEALIMKDFHH 448

Query: 60  ANIVKLKEVIRENDHL-YFIFEYMKE-NLYQLIKERNKLFPESAIRN-IMY--QILQGLA 114
           +N++ L  +    D +   +  +MK  +L   I++      +  I++ IMY   I +G+ 
Sbjct: 447 SNVLTLIGICLNLDDMPLVVLPFMKHGDLLTYIRDDQH---QPTIKDLIMYGVDIARGMD 277

Query: 115 FIHKHGFFHRDLKPENLLCMGPELVKIADFGLAREIRSRPPYTDY-----VSTRWYRAPE 169
           ++    F HRDL   N +      VK+ADFGLAR+I  +  Y+       +  +W     
Sbjct: 276 YLAGLKFVHRDLAARNCMLDEDFHVKVADFGLARDIYEKEYYSSENKKAKLPVKWMALES 97

Query: 170 VLLRSTNYSSPIDIWAVGCIMAEVYT 195
             L   NY S  D+W+ G ++ E+ T
Sbjct: 96  --LEKGNYDSKTDVWSYGVVLWELLT 25
>07940
          Length = 1336

 Score = 59.7 bits (143), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 31/93 (33%), Positives = 49/93 (52%), Gaps = 3/93 (3%)
 Frame = -3

Query: 107 YQILQGLAFIHKHGFFHRDLKPENLLCMGPELVKIADFGLAREIRSRPPYTDYVSTRW-- 164
           YQ+ +G+ ++      HRDL   N+L     ++KIADFGL R ++    Y      R   
Sbjct: 326 YQVARGMEYLASKQCIHRDLAARNVLVAEEYVLKIADFGLTRNLQQFDYYRKTTDGRLPV 147

Query: 165 -YRAPEVLLRSTNYSSPIDIWAVGCIMAEVYTL 196
            + APE L     Y+S  D+W+ G ++ E++TL
Sbjct: 146 KWMAPEALF-DRKYTSKSDVWSYGVLLWEIFTL 51
>31885
          Length = 529

 Score = 58.5 bits (140), Expect = 7e-09,   Method: Composition-based stats.
 Identities = 41/156 (26%), Positives = 75/156 (48%), Gaps = 6/156 (3%)
 Frame = -2

Query: 51  VKSLKKLNHANIVKLKEVIRENDHLYFIFE-YMKENL-YQLIKERNKLFPESAIRNIMYQ 108
           V  L +L+H  +V L    ++ + L+ + + ++  +L Y + +E +  F E  ++  + Q
Sbjct: 519 VDMLTRLDHPFLVNLWYAFQDEEDLFMVVDLFLGGDLRYHMQQEVS--FREDCVKFYLCQ 346

Query: 109 ILQGLAFIHKHGFFHRDLKPENLLCMGPELVKIADFGLAREIRSRPPYTDYVSTRWYRAP 168
           +   L ++      HRD+KP+N+L        + DF +A ++      T    TR Y AP
Sbjct: 345 LALVLDYLRSQKIVHRDIKPDNILLDEQGHCHVTDFNIATQLEDDELATSTSGTRPYMAP 166

Query: 169 EVLLRSTN----YSSPIDIWAVGCIMAEVYTLRPLF 200
           EV   + N    Y  P+D W++G  + E+   R  F
Sbjct: 165 EVYGVAINERRGYGFPVDWWSLGVSLFELLKKRRPF 58
>12453
          Length = 680

 Score = 58.2 bits (139), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 31/101 (30%), Positives = 51/101 (50%)
 Frame = +3

Query: 185 AVGCIMAEVYTLRPLFPGASEIDTIFKICQVLGTPKKTDWPEGYQLSSAMNFLWPQCIPN 244
            VGCI  E+   RPLFPG++  D +  I + LGTP +   P   +    +    P     
Sbjct: 3   GVGCIFYEMACGRPLFPGSTVEDELHLIFKTLGTPTEDSLPSISRNPDFLALNLPHYQGE 182

Query: 245 NLKTLIPNASSEAIQLLRDLLQWDPKKRPTASQALRYPYFQ 285
            L T+ P   S+ + LL   L+++ K R +A+ +L++ +F 
Sbjct: 183 ALITIAPRLDSDGLDLLAKFLKYNAKIRVSAADSLKHSFFN 305
>04852
          Length = 1462

 Score = 58.2 bits (139), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 49/203 (24%), Positives = 86/203 (42%), Gaps = 36/203 (17%)
 Frame = +1

Query: 30  IAIKKMKRKFYSWEE---CMNLREVKSLKKL-NHANIVKLKEVIRENDHLYFIFEYMKE- 84
           +A+K ++    + EE      L+ +K++KK+ +H NIV       +   L+ I E+ K  
Sbjct: 28  VAVKMLRDIVTAVEEQDFVQELQVMKAVKKMGSHINIVNFLGCCTQGGPLWVIVEFAKNG 207

Query: 85  NLYQLIKE------------------------RNKLFPESAIRNIMYQILQGLAFIHKHG 120
           NL   ++                            +     + +  +QI +G+ F+    
Sbjct: 208 NLRDFLESCRDGINGYGKFVSPQDPGWYTKTPGGHVIRRKNLLSYAFQIARGMEFLASRK 387

Query: 121 FFHRDLKPENLLCMGPELVKIADFGLAREIRSRPPYTDYVSTRW-------YRAPEVLLR 173
             HRDL   N+L     ++KIADFGL+R         DY   R        + APE L  
Sbjct: 388 CIHRDLAARNVLVTEEHVLKIADFGLSRT-------GDYYKKRSGGRLPVKWMAPEALF- 543

Query: 174 STNYSSPIDIWAVGCIMAEVYTL 196
              Y++  D+W+ G ++ E+++L
Sbjct: 544 DMRYTTKSDVWSFGVVLWEIFSL 612
>01106
          Length = 878

 Score = 57.4 bits (137), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 43/144 (29%), Positives = 75/144 (52%), Gaps = 14/144 (9%)
 Frame = +3

Query: 3   RYTTIKQLGDGTYGSVLLGRSIESGELIAIKKMKRKFYSWEECMNLREVKSLKKLNHANI 62
           RY  I++LG G + +V L   +     +A+K +K   +  E  ++  EVK LK +  +++
Sbjct: 321 RYHVIRKLGWGHFSTVWLCWDLTCKRFVALKVVKSAQHYTETALD--EVKLLKCVRESDV 494

Query: 63  V---KLKEVIREND---------HLYFIFEYMKENLYQLIKERN-KLFPESAIRNIMYQI 109
               + K V   +D         H+  +FE +  NL +LI   N +  P   ++ I+ Q+
Sbjct: 495 ADPARAKCVQLLDDFKISGVNGTHVAMVFEVLGYNLLKLIIRSNYQGIPIHNVKLIIRQV 674

Query: 110 LQGLAFIH-KHGFFHRDLKPENLL 132
           L+GL+++H K    H D+KPEN+L
Sbjct: 675 LEGLSYMHAKCRIIHTDIKPENIL 746
>13066
          Length = 551

 Score = 57.4 bits (137), Expect = 2e-08,   Method: Composition-based stats.
 Identities = 43/145 (29%), Positives = 67/145 (46%), Gaps = 6/145 (4%)
 Frame = +3

Query: 49  REVKSLKKLNHANIVKLKEVIRENDHLYFIFEYMKE--NLYQLIKERNKLFPESAIRNIM 106
           RE+  L KL+H  I+++  +++      FIF    E  +L   I+E      E   +   
Sbjct: 123 RELDLLTKLDHPYIIQIHSILQRXPK-NFIFMRFAERGDLLTYIQEVG-FVKEKQAKIWF 296

Query: 107 YQILQGLAFIHKHGFFHRDLKPENLLCMGPELVKIADFGLA----REIRSRPPYTDYVST 162
           YQ+   L ++H +   HRDLK EN+L      VK+ADFG A     E   +     Y  +
Sbjct: 297 YQMTTALNYLHSYDVAHRDLKCENILLSSHFNVKLADFGFACACITESGEKYMSRTYCGS 476

Query: 163 RWYRAPEVLLRSTNYSSPIDIWAVG 187
             Y APE++  +       D W++G
Sbjct: 477 AAYAAPEIVYGAPYAPKVADAWSLG 551
>21079
          Length = 878

 Score = 57.0 bits (136), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 36/135 (26%), Positives = 65/135 (48%), Gaps = 4/135 (2%)
 Frame = +1

Query: 59  HANIVKLKEVIRENDHLYFIFEYMKEN-LYQLIKERNKLFPESAIRNIMYQILQGLAFIH 117
           H  ++ L +       +  + E++    L++ +   + +  E    + + QI  G+ ++H
Sbjct: 1   HPKLLMLWDAFEAPRTMVLVMEFVGAGELFERVIRDDFVLTERDCVHFVRQICSGVGYMH 180

Query: 118 KHGFFHRDLKPENLLCM--GPELVKIADFGLAREIRSRPPYTDYVSTRWYRAPEVL-LRS 174
                H DLKPEN+LC+      +KI DFGLAR  +          T  + APEV+    
Sbjct: 181 TQSILHLDLKPENVLCVSDNSNQIKIIDFGLARFYKPGDSLQVLFGTPEFIAPEVVNYDE 360

Query: 175 TNYSSPIDIWAVGCI 189
            N+++  D+W++G I
Sbjct: 361 INFTT--DMWSIGVI 399
>11780
          Length = 1713

 Score = 53.1 bits (126), Expect(2) = 5e-08,   Method: Compositional matrix adjust.
 Identities = 46/170 (27%), Positives = 79/170 (46%), Gaps = 8/170 (4%)
 Frame = +3

Query: 10  LGDGTYGSVLLGRSIESGELIAIKKMKRKFYSWEECMNLREVKSLKKLNHANIVKLKEVI 69
           +G G +G V  G  +  G+ +AIK++K K     E   L+E   +  L H N+V+L  V+
Sbjct: 621 IGKGDFGDVYKG--MYRGQPVAIKQLKDK--DRGEQSFLQEASVMTSLRHDNLVRLIGVV 788

Query: 70  RENDHLYFIFEYM-KENLYQLIKERNK-LFPESAIRNIMYQILQGLAFIHKHGFFHRDLK 127
              + ++ + E+M K NL + ++ R + +  +    N        + ++      HRDL 
Sbjct: 789 L-GETIFLVTEFMGKGNLVEYLRSRGRSVITKKDQINFATDTCAAMEYLESKRLVHRDLA 965

Query: 128 PENLLCMGPELVKIADFGLAREIRSRPPYTDYVST------RWYRAPEVL 171
             N+L       K++DFGLA+       + D+  T      +W  APE L
Sbjct: 966 ARNVLVHDDGKAKVSDFGLAK-------FGDFSQTSVKFPIKW-TAPEAL 1091

 Score = 22.3 bits (46), Expect(2) = 5e-08,   Method: Compositional matrix adjust.
 Identities = 9/37 (24%), Positives = 20/37 (54%), Gaps = 1/37 (2%)
 Frame = +1

Query: 177  YSSPIDIWAVGCIMAEVYTL-RPLFPGASEIDTIFKI 212
            ++S  D+W+ G ++ E+Y+  R  +P     D +  +
Sbjct: 1105 FTSKSDMWSFGILLWEIYSFGRVPYPRIPLTDVVMHV 1215
>20640
          Length = 1492

 Score = 55.5 bits (132), Expect = 7e-08,   Method: Compositional matrix adjust.
 Identities = 35/110 (31%), Positives = 55/110 (50%), Gaps = 7/110 (6%)
 Frame = +1

Query: 120 GFFHRDLKPENLLCMGPELVKIADFGLAREIRSRPPY----TDYVSTRWYRAPEVLLRST 175
           G+ HRDL   N L     +VKI+DFGLAR + S   Y     D +  RW     +L    
Sbjct: 4   GYVHRDLATRNCLVGHDLVVKISDFGLARSVHSVDYYRGSEHDAIPIRWMPLEAILY--N 177

Query: 176 NYSSPIDIWAVGCIMAEV--YTLRPLFP-GASEIDTIFKICQVLGTPKKT 222
            +S+  D+W+ G ++ E+  + L+P +     E+    K  +VL  P++T
Sbjct: 178 KFSTQSDVWSFGVVLWEIFAFALQPYYGLTHEEVVRFVKEGKVLACPERT 327
>17300
          Length = 480

 Score = 55.1 bits (131), Expect = 1e-07,   Method: Composition-based stats.
 Identities = 35/98 (35%), Positives = 49/98 (50%), Gaps = 8/98 (8%)
 Frame = +1

Query: 109 ILQGLAFIHKHGFFHRDLKPENLLCMGPELVKIADFGLAREIRSRPPYTDY------VST 162
           I  G+  +   G+ HRDL   N+L     + K+ADFGL+REI S      Y      +  
Sbjct: 1   ISSGMGXLADMGYVHRDLAARNILVNEILVCKVADFGLSREIESDTTEGAYTTKGGKIPV 180

Query: 163 RWYRAPEVLLRSTNYSSPIDIWAVGCIMAEV--YTLRP 198
           RW  APE +     ++S  D+W+ G +M EV  Y  RP
Sbjct: 181 RW-TAPEAIAYR-KFTSASDVWSFGVVMWEVMSYGERP 288
>36481
          Length = 806

 Score = 54.3 bits (129), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 37/129 (28%), Positives = 69/129 (53%), Gaps = 7/129 (5%)
 Frame = +2

Query: 11  GDGTYGSVLLGRSIESGELIAIKKMKRKFYSWEECMNLREVKSLKKLN----HAN--IVK 64
           G+GT+G V+  + +  G+ IA+K +K     + E   L E+  L+KL     HA    V+
Sbjct: 389 GEGTFGKVVQCKDLLKGDDIALKIIK-NVDKYREAAKL-EINVLEKLREKDPHAKHMCVQ 562

Query: 65  LKEVIRENDHLYFIFEYMKENLYQLIKERN-KLFPESAIRNIMYQILQGLAFIHKHGFFH 123
           + +    + H+   F  +  +++  +K+ +   +P   +R+I YQ+   + F+H++   H
Sbjct: 563 MLDWFDYHGHVCISFHMLGLSVFDFLKDNSYGAYPIEQVRHISYQLCYAVNFLHENQLTH 742

Query: 124 RDLKPENLL 132
            DLKPEN+L
Sbjct: 743 TDLKPENIL 769
>26711
          Length = 405

 Score = 53.1 bits (126), Expect = 3e-07,   Method: Composition-based stats.
 Identities = 36/111 (32%), Positives = 59/111 (53%), Gaps = 4/111 (3%)
 Frame = -2

Query: 105 IMYQILQGLAFIHKHGFFHRDLKPENLLCMGPEL--VKIADFGLAREIRSRPPYTDYVS- 161
           ++ Q+L  L  +H  G  H DLKP NLL  G +L  V++ DFGLAR++   PP   +++ 
Sbjct: 401 VVKQVLDILQHVHAQGVVHMDLKPSNLLLSGDKLDSVQLIDFGLARKL--YPPQETFLNH 228

Query: 162 -TRWYRAPEVLLRSTNYSSPIDIWAVGCIMAEVYTLRPLFPGASEIDTIFK 211
            T  + +PE  L     S+  D+W VG +   + + +  F   S  +++ K
Sbjct: 227 GTPGFTSPEA-LDVKPISTASDVWGVGVLAYILLSGQSPFQADSATESLKK 78
>24241
          Length = 413

 Score = 51.6 bits (122), Expect = 1e-06,   Method: Composition-based stats.
 Identities = 33/112 (29%), Positives = 63/112 (56%), Gaps = 3/112 (2%)
 Frame = -2

Query: 7   IKQLGDGTYGSVLLGRSIESGELIAIKKMK-RKFYSWEECMNLREVKSLKKLNHAN-IVK 64
           + ++G+GTYG V   R   +G  +A+KK++ R          +RE+  L++L H   +V 
Sbjct: 328 LSKIGEGTYGVVYKCRHRATGRKLAMKKIRLRGSEDGVPSSAIREIAMLRELRHTQXLVC 149

Query: 65  LKEVIRENDHLYFIFEYMKENLYQLIKERNKLFPESAIRN-IMYQILQGLAF 115
           L++VI E++ L+ +FE++  +L   I +    FPE  + +  + +I+ G+ F
Sbjct: 148 LEDVIMEDERLFLVFEFLSMDLKMYIDK----FPEGVVLDRRLVKIVTGINF 5
>20559
          Length = 430

 Score = 51.6 bits (122), Expect = 1e-06,   Method: Composition-based stats.
 Identities = 27/82 (32%), Positives = 51/82 (62%), Gaps = 3/82 (3%)
 Frame = -2

Query: 1   MNRYTTIKQLGDGTYGSVLLGRSIESGELIAIKKMKRKFYSWEECM---NLREVKSLKKL 57
           M +Y  ++++G+GTYG+V   ++ E+ E++A+K++  +    +E +    LRE+  LK+L
Sbjct: 378 MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRV--RLDDDDEGVPSSALREICLLKEL 205

Query: 58  NHANIVKLKEVIRENDHLYFIF 79
            H NIV+L +V+     L  +F
Sbjct: 204 KHRNIVRLHDVLHSERKLTLVF 139
>16003
          Length = 926

 Score = 51.2 bits (121), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 33/87 (37%), Positives = 48/87 (55%)
 Frame = -1

Query: 198 PLFPGASEIDTIFKICQVLGTPKKTDWPEGYQLSSAMNFLWPQCIPNNLKTLIPNASSEA 257
           P  PG +++D + KI  +LGTP +T+WP    L   + F    C    LK +   A  + 
Sbjct: 911 PFLPGDTDLDQLGKIFNMLGTPTETEWPAVTSLPDYIQF--KHCQKQPLKEIFTAAGDDL 738

Query: 258 IQLLRDLLQWDPKKRPTASQALRYPYF 284
           ++LL  LL  +P  R TA+QAL+ PYF
Sbjct: 737 LELLDKLLAMNPLHRCTATQALKMPYF 657
>11404
          Length = 563

 Score = 50.8 bits (120), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 45/144 (31%), Positives = 67/144 (46%), Gaps = 12/144 (8%)
 Frame = +1

Query: 2   NRYTTIKQLGDGTYGSVLLGRSIESGELIAIKKMKRK--FYSWEECMNLREVKSLKKLNH 59
           +RY     +G G++G V+        E +AIK +K K  F +  +     EVK L+ +N 
Sbjct: 139 DRYEIDSLIGKGSFGQVVKAYDHTDNEQVAIKIIKNKKPFLNQAQI----EVKLLEMMNR 306

Query: 60  AN------IVKLKEVIRENDHLYFIFEYMKENLYQLIKERN-KLFPESAIRNIMYQILQG 112
            +      IV+LK       HL  +FE +  NLY L++  N +    +  R    Q+   
Sbjct: 307 HDTDNKYYIVRLKRHFMFRSHLCLVFELLSYNLYDLLRNTNFRGVSLNLTRKFAQQLCTA 486

Query: 113 LAFIH--KHGFFHRDLKPEN-LLC 133
           L F+   +    H DLKPEN LLC
Sbjct: 487 LLFLATPEMSIIHCDLKPENILLC 558
>29360
          Length = 363

 Score = 49.7 bits (117), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 37/115 (32%), Positives = 61/115 (53%), Gaps = 8/115 (6%)
 Frame = +3

Query: 26  SGELIAIKKMKRK-FYSWEECMNLREVKSLKKLNHA-----NIVKLKEVIRENDHLYFIF 79
           + E++AIK +K    Y+ +  +   EV  L++L+       N V+  E  +  +H   +F
Sbjct: 24  TSEIVAIKILKNHPSYARQGQI---EVSILQRLSQESADDYNFVRAFECFQHKNHTCLVF 194

Query: 80  EYMKENLYQLIKERNKL--FPESAIRNIMYQILQGLAFIHKHGFFHRDLKPENLL 132
           E +++NLY  +K+ NK    P   IR I  Q+L  L  + + G  H DLKPEN++
Sbjct: 195 EMLEQNLYDFLKQ-NKFQPLPLKYIRPITQQVLTALRKLKQLGLIHADLKPENIM 356
>00715
          Length = 1788

 Score = 48.1 bits (113), Expect = 9e-06,   Method: Compositional matrix adjust.
 Identities = 42/164 (25%), Positives = 66/164 (40%), Gaps = 32/164 (19%)
 Frame = +1

Query: 53  SLKKLNHANIVKLKEVIRENDHLYFIFEYMKE-NLYQLIKERNKLFPESAIRNIMYQILQ 111
            L+ +N  +I+    + R  D  +   EY+   NL  ++ +  +    S   ++  Q+ +
Sbjct: 94  GLRHVNVVSILGATSLHRFEDGAWLAMEYVGPLNLQTILNDHQQDIDSSMRLSLALQMAR 273

Query: 112 GLAFIHKHGFFHRDLKPENLLCMGPELVKIADFGLAREIRSRPPYTDY------------ 159
           GL ++H     H DLKP N L      ++IADFG   ++   P   D             
Sbjct: 274 GLHYLHSINIVHLDLKPANCLLTRDLKLRIADFGCCHQL--TPTGLDMGEREGGMAGNEL 447

Query: 160 ----VSTRW---------YRAPEVL------LRSTNYSSPIDIW 184
               V   W         YRAPE+L      +RS  YS  I +W
Sbjct: 448 ELTPVQGAWKNELAGTLAYRAPELLKGLQPSVRSDVYSLGITLW 579
>13078
          Length = 773

 Score = 47.0 bits (110), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 40/143 (27%), Positives = 67/143 (46%), Gaps = 20/143 (13%)
 Frame = -1

Query: 174 STNYSSPIDIWAVGCIMAEVYTLRPLFPGASEIDTIFKICQVLGT-----PKKT------ 222
           S  +S P D+W++GCIM E+YT   LF      + +  + ++LG+      KKT      
Sbjct: 755 SWGWSQPCDVWSIGCIMFELYTGYTLFQTHDNKEHLAMMERILGSLPYRMAKKTKKQKYF 576

Query: 223 -----DWPEGYQLSSAMNFLWPQCIPNNLKTLIPNASSEAIQLLRDL----LQWDPKKRP 273
                DW E    SSA  ++     P  L+  + +  +E  Q L DL    L ++   R 
Sbjct: 575 YHGRLDWDEK---SSAGRYVRDNVKP--LRRYVKDPDNEDHQQLFDLMDKMLSYEVSTRY 411

Query: 274 TASQALRYPYFQIGHPLGIISKD 296
           +  QA+R+P+F+  +   ++  D
Sbjct: 410 SLRQAMRHPFFRKLYEGDVVRGD 342
>22005
          Length = 873

 Score = 47.0 bits (110), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 58/248 (23%), Positives = 95/248 (38%), Gaps = 59/248 (23%)
 Frame = +1

Query: 8   KQLGDGTYGSV----LLGRSIESGELIAIK------KMKRKFYSWEECMNL-REVKSLKK 56
           + +G G +G V     LG +   GELI  K      KM ++  S +   +  RE   +  
Sbjct: 1   RDIGQGAFGRVSKLKFLGLASLVGELIPEKRP*LL*KMLKEDASEDLQSDFEREASLMAD 180

Query: 57  LNHANIVKLKEVIRENDHLYFIFEYMKE----NLYQLIKERNKLFPESAIRNIMY----- 107
            +H NIVKL  V      +  +FE+M +    +  +L    N   P S  +N++      
Sbjct: 181 FDHPNIVKLLGVCAIGKPMCLLFEFMSKGDLNDFLRLCSPENYNLPVSRSQNLVVDLEDG 360

Query: 108 -----------------------------------QILQGLAFIHKHGFFHRDLKPENLL 132
                                              QI  G+A++ +  + HRDL    + 
Sbjct: 361 LRVEVEAEECEKDTQSEDRDCSGMLXTKDQLYISQQISAGMAYLAQKDYVHRDLATRTVX 540

Query: 133 CMGPELVKIADFGLAREIRSRPPY----TDYVSTRWYRAPEVLLRSTNYSSPIDIWAVGC 188
                   I+DFGLAR + S   Y     D +  RW     +L   + +S+  D+W+ G 
Sbjct: 541 -SRTT*S*ISDFGLARSVHSVDYYRGSEQDAIPIRWMPLEAILY--SKFSTQSDVWSFGV 711

Query: 189 IMAEVYTL 196
           ++ E+  L
Sbjct: 712 VLWEILPL 735
>11185
          Length = 473

 Score = 47.0 bits (110), Expect = 3e-05,   Method: Composition-based stats.
 Identities = 33/119 (27%), Positives = 53/119 (44%), Gaps = 23/119 (19%)
 Frame = +1

Query: 100 SAIRNIMYQILQGLAFIHKHGFFHRDLKPENLLCMGPELVKIADFGLAR----------- 148
           ++IR+    ++ GL +IH  G    DL+P  +L     ++K ADFGL++           
Sbjct: 1   TSIRDFGIHLVTGLHYIHSLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFF 180

Query: 149 ---------EIRSRPPYTDYVSTR---WYRAPEVLLRSTNYSSPIDIWAVGCIMAEVYT 195
                     I+S       V T     Y APEV  +    S   D+WA+GC+  E+++
Sbjct: 181 KFAEAGDQWNIQSAEEMMKQVPTSGSPTYMAPEV-FQGAEPSIMSDLWALGCVFYEMFS 354
>26009
          Length = 886

 Score = 46.2 bits (108), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 17/50 (34%), Positives = 30/50 (60%)
 Frame = +3

Query: 93  RNKLFPESAIRNIMYQILQGLAFIHKHGFFHRDLKPENLLCMGPELVKIA 142
           RNK       +++M Q++  L F+H     HRD+KPEN+L + P+  +++
Sbjct: 690 RNKACGSREAKSVMKQLVSALDFMHSKQLVHRDIKPENVLILTPDFSRVS 839
>21800
          Length = 855

 Score = 45.1 bits (105), Expect = 9e-05,   Method: Compositional matrix adjust.
 Identities = 23/61 (37%), Positives = 37/61 (60%), Gaps = 2/61 (3%)
 Frame = +2

Query: 74  HLYFIFEYMKENLYQLIKERN-KLFPESAIRNIMYQILQGLAFIH-KHGFFHRDLKPENL 131
           H+  +FE +  NL +LI   N +  P   ++ I+ Q+L+GL ++H K    H D+KPEN+
Sbjct: 551 HVCMVFEVLGYNLLKLIIRSNYQGIPVHNVKLIIRQVLEGLNYLHAKCNIIHTDIKPENI 730

Query: 132 L 132
           L
Sbjct: 731 L 733
>12786
          Length = 460

 Score = 44.3 bits (103), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 26/105 (24%), Positives = 47/105 (44%), Gaps = 22/105 (20%)
 Frame = -3

Query: 108 QILQGLAFIHKHGFFHRDLKPENLLCMGPELVKIADFGLAREIRSRPPYT---DYVSTRW 164
           ++L+ +  +H  G  H DLKP N + +   L K+ DFG+A  ++           V T  
Sbjct: 386 EMLRAVKALHNEGVIHSDLKPANFMLVAGNL-KLIDFGIANTLQQDKTSVLKDSRVGTPS 210

Query: 165 YRAPEVLLRSTNYSSP-------------------IDIWAVGCIM 190
           Y +PE ++ + + S+                     D+W++GCI+
Sbjct: 209 YMSPEAIMAACDDSADDSMEEDGHRTKPKYKVGVRSDVWSLGCIL 75
>28157
          Length = 400

 Score = 44.3 bits (103), Expect = 1e-04,   Method: Composition-based stats.
 Identities = 42/133 (31%), Positives = 71/133 (53%), Gaps = 10/133 (7%)
 Frame = +3

Query: 30  IAIKKMKRKFYSWEECMNLREVKSLKKLNHANIVKLKEVIRENDH-LYFIFEYMKE-NLY 87
           +A+K+++ +    E+   ++E+K L +++H NIV L    R  DH +  + EY +  +LY
Sbjct: 9   VAVKRIESE---QEKKSFMQELKQLSRVSHPNIVCLYGACR--DHPVCLVMEYAEGGSLY 173

Query: 88  QLIKERNKLFPESAIRNIMYQILQ---GLAFIH---KHGFFHRDLKPENLLCM--GPELV 139
            ++       P+    + M  +LQ   G+ ++H        HRDLKP NLL +  G +L 
Sbjct: 174 NVLHGSGPQ-PQYTAAHAMNWLLQCALGVEYLHGMKPKALIHRDLKPPNLLLIQCGTKL- 347

Query: 140 KIADFGLAREIRS 152
           KI DFG A +I +
Sbjct: 348 KICDFGTACDIHT 386
>07836
          Length = 1478

 Score = 44.3 bits (103), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 56/212 (26%), Positives = 87/212 (41%), Gaps = 25/212 (11%)
 Frame = -1

Query: 27   GELIAIKKMKRKFYSWEECMNLREVKSLKK--LNHANIVKLKEVIREND----HLYFIFE 80
            GE +A+K     F++ EE    RE +  +   L H NI+       +       L+ I +
Sbjct: 1478 GENVAVKI----FFTTEEASWFRETELYQTVLLRHENILGFIAADIKGTGSWTQLFLITD 1311

Query: 81   YMKE-NLYQLIKERNKLFPESAIRNIMYQILQGLAFIH--------KHGFFHRDLKPENL 131
            Y +  +L+  +  R  +   S +  + +  + GLA +H        K    HRD+K +N+
Sbjct: 1310 YHENGSLHDYLLSR--VLDSSEMLALAHSAICGLAHLHIEIFGTRGKPAIAHRDIKSKNI 1137

Query: 132  LCMGPELVKIADFGLAREIRSRPPYTDYV-----STRWYRAPEV---LLRSTNYSS--PI 181
            L        IAD GLA    S     D        T+ Y APEV   LL   N+ +    
Sbjct: 1136 LVKKNGTCCIADLGLAVRYISESNEVDVAPNPRQGTKRYMAPEVLEMLLNVKNFDAFKQA 957

Query: 182  DIWAVGCIMAEVYTLRPLFPGASEIDTIFKIC 213
            D++A G +M E+     +   A E    F  C
Sbjct: 956  DMYAFGLVMWEIARCCVIGGVAEEYQVPFYNC 861
>02638
          Length = 1490

 Score = 43.9 bits (102), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 36/128 (28%), Positives = 53/128 (41%), Gaps = 3/128 (2%)
 Frame = +1

Query: 160 VSTRWYRAPEVLLRSTNYSSPIDIWAVGCIMAEVYTLRPLFPG---ASEIDTIFKICQVL 216
           + T  + APEVL R  +Y    D+W+VGC+M E+ T RP +     ++ +  IFKI   +
Sbjct: 19  LGTIAFMAPEVL-RGESYGRACDVWSVGCVMIEMCTCRPPWNSHDISNHLALIFKIASSV 195

Query: 217 GTPKKTDWPEGYQLSSAMNFLWPQCIPNNLKTLIPNASSEAIQLLRDLLQWDPKKRPTAS 276
             P                      IP N+       S     L+   L+ D   RP+A 
Sbjct: 196 DPPP---------------------IPENM-------SPPVRDLMLRCLEQDSDFRPSAK 291

Query: 277 QALRYPYF 284
             L +P F
Sbjct: 292 DLLMHPLF 315
>21433
          Length = 590

 Score = 43.5 bits (101), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 30/93 (32%), Positives = 44/93 (47%)
 Frame = +2

Query: 106 MYQILQGLAFIHKHGFFHRDLKPENLLCMGPELVKIADFGLAREIRSRPPYTDYVSTRWY 165
           +YQ+   L + H     HRD+KPENLL      +KIADFG +    S    T    T  Y
Sbjct: 185 IYQLSSALEYCHYRKVIHRDIKPENLLLGLKGDLKIADFGWSVHAPSS-RRTTMCGTLDY 361

Query: 166 RAPEVLLRSTNYSSPIDIWAVGCIMAEVYTLRP 198
             PE ++    +   +D+W++G +  E     P
Sbjct: 362 LPPE-MVEGKTHDENVDLWSLGVLCYEFLVGTP 457
>07291
          Length = 833

 Score = 42.7 bits (99), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 25/93 (26%), Positives = 48/93 (51%), Gaps = 5/93 (5%)
 Frame = +1

Query: 108 QILQGLAFIHKHGFFHRDLKPENLLCMGPELVKIADFGLAREIRSRPPYTDYVS-----T 162
           QI  G+A++ +    HR+L   N +      ++++D+G+   +  +  YT   S      
Sbjct: 73  QIADGMAYLQEVKVVHRNLAARNCIVTEDGRLQLSDYGVTGSLFPQSYYTADDSPARDLV 252

Query: 163 RWYRAPEVLLRSTNYSSPIDIWAVGCIMAEVYT 195
           +W  APE  + + ++SS  D+WA G ++ E+ T
Sbjct: 253 KWM-APET-IDNFHFSSKSDVWAFGVVLWELLT 345
>16708
          Length = 1397

 Score = 42.7 bits (99), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 53/220 (24%), Positives = 90/220 (40%), Gaps = 28/220 (12%)
 Frame = -1

Query: 7    IKQLGDGTYGSVLLGRSIESGELIAIKKMKRKFYSWEECMNLREVKS---LKKLNHANIV 63
            ++ LG G +G V   R + + E  A+K      +S +E   L  ++    L ++  A + 
Sbjct: 1388 LQVLGKGVFGKVYEARLLSTHEKAALKTSILCHHSLDEVEALGRIEGGFYLAQMFGAWVT 1209

Query: 64   KLKEVIRENDHLYFIFEYMKENLYQLIKERNKLFP-----ESAIRNIMYQILQGLAFIHK 118
             L    + N  L+F       N+Y   K  NK  P      + +  I  Q +  L  IH+
Sbjct: 1208 CLP-FPKMNILLHFYEMGPLCNVYAHYK--NKEMPIRWSNPAMVCCIAGQXVCALEHIHE 1038

Query: 119  HGFFHRDLKPENLLCMGPELVKIADFGLAREIRSRPPYTDYVS-------TRWYRAPEVL 171
             G  H D+K +N+L       K+ D+G+A+  +  P  T+  S       T + R P  +
Sbjct: 1037 LGVVHMDVKADNVLVDAHGNCKLTDYGIAQLYKVYPAPTETHSSGCTNKRTFYTRPPATM 858

Query: 172  LRSTNYSSPID------------IWAV-GCIMAEVYTLRP 198
              S  +S   D            +W + G ++  V+  RP
Sbjct: 857  TPSERFSEEGDGIGTDYFRLGQMLWTLTGAVLLHVWVSRP 738
>18481
          Length = 437

 Score = 42.7 bits (99), Expect = 5e-04,   Method: Composition-based stats.
 Identities = 28/72 (38%), Positives = 38/72 (52%), Gaps = 4/72 (5%)
 Frame = -1

Query: 84  ENLYQLIKERNKLFPESAIRNIMYQILQGLAFIHKHGFFHRDLKPENLLCMG----PELV 139
           E L+ + K R   F    I  +  Q+L  L FIH+  F HRDLKP+N L MG       +
Sbjct: 236 EELFVICKRR---FTLKTILMVSDQLLSRLEFIHQKCFIHRDLKPDNFL-MGLGRHCHRL 69

Query: 140 KIADFGLAREIR 151
            I DFGL++  +
Sbjct: 68  YIIDFGLSKRYK 33
>18996
          Length = 491

 Score = 41.2 bits (95), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 28/87 (32%), Positives = 46/87 (52%), Gaps = 7/87 (8%)
 Frame = +2

Query: 123 HRDLKPENLLCMGPELVKIADFGLAREIRSRPPYTDY----VSTRWYRAPEVLLRSTNYS 178
           HRDL   N+L +    VKI+DFGLA+   +   Y       +  +WY +PE  + +  +S
Sbjct: 5   HRDLAARNIL-VDRSCVKISDFGLAQFANADGYYYGISQRDIPIKWY-SPEA-IETCKFS 175

Query: 179 SPIDIWAVGCIMAEVYT---LRPLFPG 202
           S  D+W+ G  + E+++   +  L PG
Sbjct: 176 SYSDVWSYGVTLFEMFSRGEIPNLLPG 256
>17253
          Length = 483

 Score = 40.8 bits (94), Expect = 0.002,   Method: Composition-based stats.
 Identities = 33/149 (22%), Positives = 65/149 (43%), Gaps = 13/149 (8%)
 Frame = -1

Query: 28  ELIAIKKMKRKFYSWEECMNLREVKSLKKL-NHANIVKLKEVIRENDHLYFIFEYM-KEN 85
           + +A+K         E+   LRE+  ++KL  H N+V        +D    + E+    +
Sbjct: 465 DTVAVKTHNEAATDAEKSEFLRELSIMRKLPRHPNVVSFMGCCTMSDPALILMEFCCHGD 286

Query: 86  LYQLIKERN---KLFPESAIRNIM--------YQILQGLAFIHKHGFFHRDLKPENLLCM 134
           L   +++R     +F  S   ++           + +G+A +  +   HRD+   N+L  
Sbjct: 285 LLSFLRKRRPDRTVFLTSTANDLTARDFFSFALHVARGMAHVANNKIVHRDVAARNVLIS 106

Query: 135 GPELVKIADFGLAREIRSRPPYTDYVSTR 163
              + K++DFGL+R +  +    + VS R
Sbjct: 105 ERNVCKVSDFGLSRRVGDQNDVYEIVSRR 19
>37602
          Length = 804

 Score = 40.0 bits (92), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 23/70 (32%), Positives = 33/70 (47%)
 Frame = -1

Query: 75  LYFIFEYMKENLYQLIKERNKLFPESAIRNIMYQILQGLAFIHKHGFFHRDLKPENLLCM 134
           L+   EY      Q I        E  I  +  + L+GL ++H+ G  HRD+K  N+L  
Sbjct: 294 LWIAMEYCGGGSMQDIYHVTGPLTEPQIAFVCRETLKGLHYLHRRGKMHRDIKGANILLT 115

Query: 135 GPELVKIADF 144
               VK+ADF
Sbjct: 114 EEGDVKLADF 85
>00638
          Length = 1595

 Score = 37.0 bits (84), Expect = 0.023,   Method: Compositional matrix adjust.
 Identities = 23/82 (28%), Positives = 44/82 (53%), Gaps = 3/82 (3%)
 Frame = +2

Query: 50  EVKSLKKL-NHANIVKLKEVIRE--NDHLYFIFEYMKENLYQLIKERNKLFPESAIRNIM 106
           E+K L+ L    N++ L  ++++  +     IFE++    +   K+  + F +  IR  +
Sbjct: 266 EIKILENLRGGTNVITLLAIVKDPVSRTPALIFEHVNNTDF---KQLYQTFTDYDIRFYL 436

Query: 107 YQILQGLAFIHKHGFFHRDLKP 128
           Y++++ L F H  G  HRD+KP
Sbjct: 437 YELMKALDFCHSMGIMHRDVKP 502
>37063
          Length = 455

 Score = 37.0 bits (84), Expect = 0.023,   Method: Composition-based stats.
 Identities = 28/78 (35%), Positives = 37/78 (47%), Gaps = 13/78 (16%)
 Frame = -2

Query: 126 LKPENLLCMGPELV---KIADFGLAREIR------SRPPYTDYVSTRWYRAPEVLL---- 172
           LKPEN+LC   + V   KI DF LA  I         P     V +  Y APEV+     
Sbjct: 454 LKPENILCEHLDEVVPLKICDFDLASGINCDGDGTKTPELLTPVGSAEYMAPEVVDAWVG 275

Query: 173 RSTNYSSPIDIWAVGCIM 190
            S +Y    D+W++G I+
Sbjct: 274 ESFSYDKRCDMWSLGIIL 221
>05084
          Length = 1324

 Score = 37.0 bits (84), Expect = 0.026,   Method: Compositional matrix adjust.
 Identities = 27/85 (31%), Positives = 39/85 (45%)
 Frame = +2

Query: 200 FPGASEIDTIFKICQVLGTPKKTDWPEGYQLSSAMNFLWPQCIPNNLKTLIPNASSEAIQ 259
            PG S +D + +I +VLGTP +    E     S   F   +  P   K   P    EAIQ
Sbjct: 2   LPGDSGVDQLVEIIKVLGTPTREQIREMNPNYSEFKFPQIKAHPWT-KVFRPRTPPEAIQ 178

Query: 260 LLRDLLQWDPKKRPTASQALRYPYF 284
           L+  LL++ P  R    +A  + +F
Sbjct: 179 LVSRLLEYTPSARIQPMEACAHAFF 253
>31757
          Length = 540

 Score = 35.8 bits (81), Expect = 0.057,   Method: Compositional matrix adjust.
 Identities = 14/24 (58%), Positives = 18/24 (75%)
 Frame = -2

Query: 479 QSSAKQHYLKHSRYLPGINIRNGV 502
            +SAKQHY+  +RYLPGIN +N  
Sbjct: 344 NNSAKQHYISKARYLPGINPKNSA 273
>17806
          Length = 433

 Score = 35.4 bits (80), Expect = 0.070,   Method: Composition-based stats.
 Identities = 30/123 (24%), Positives = 55/123 (44%), Gaps = 10/123 (8%)
 Frame = +1

Query: 7   IKQLGDGTYGSVLL--GRSIESG---ELIAIKKMKRKFYSWEECMNLREVKSLKKLNHAN 61
           +K+LG G +G V+      I +G     + +K +K      E+ +   EV   ++L+H N
Sbjct: 64  LKELGTGWFGKVIESDAERITTGVSRSKVVVKMLKDDATKDEQLLFFEEVAPFRELDHPN 243

Query: 62  IVKLKEVIRENDHLYFIFE-----YMKENLYQLIKERNKLFPESAIRNIMYQILQGLAFI 116
           IV+L     E + +  + E      +K+ L     ++  L  ++ +      I  GLA +
Sbjct: 244 IVRLLGQCTEMNPMLMLMECAALGNLKQYLRNHRHQQAMLIQKNRLLKFAMDISSGLACL 423

Query: 117 HKH 119
           H H
Sbjct: 424 HGH 432
>18929
          Length = 440

 Score = 30.8 bits (68), Expect = 1.8,   Method: Compositional matrix adjust.
 Identities = 14/36 (38%), Positives = 22/36 (61%)
 Frame = +1

Query: 249 LIPNASSEAIQLLRDLLQWDPKKRPTASQALRYPYF 284
            I   S E  Q++R ++  DP++RPTA+Q L +P  
Sbjct: 34  FINTISVELQQVIRRMMSPDPRQRPTANQLLAHPTL 141
>29722
          Length = 352

 Score = 30.0 bits (66), Expect = 2.8,   Method: Compositional matrix adjust.
 Identities = 13/27 (48%), Positives = 19/27 (70%)
 Frame = -3

Query: 259 QLLRDLLQWDPKKRPTASQALRYPYFQ 285
           +LLR +L  DP KRP+ ++ LR PY +
Sbjct: 257 ELLRAMLYQDPAKRPSINRILRDPYIR 177
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|28916677|ref|NP_803126.1|
calcium/calmodulin-dependent protein kinase II alpha isoform 2 [Mus
musculus]
         (478 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

15910                                                                 194   9e-50
01392                                                                 123   2e-28
12721                                                                 122   3e-28
01707                                                                 107   1e-23
01060                                                                 104   8e-23
09606                                                                 103   2e-22
03240                                                                 101   5e-22
30755                                                                 100   1e-21
21079                                                                  92   1e-21
13592                                                                  99   5e-21
17975                                                                  98   9e-21
18484                                                                  97   2e-20
14420                                                                  96   4e-20
26711                                                                  94   2e-19
14126                                                                  92   4e-19
00300                                                                  88   6e-18
21433                                                                  74   1e-16
13212                                                                  79   3e-15
13066                                                                  76   3e-14
09007                                                                  71   1e-12
01966                                                                  71   1e-12
31885                                                                  70   2e-12
00392                                                                  69   3e-12
28638                                                                  64   4e-12
00486                                                                  68   8e-12
27405                                                                  68   1e-11
19761                                                                  67   1e-11
01718                                                                  67   2e-11
38560                                                                  65   5e-11
18921                                                                  65   8e-11
06405                                                                  64   2e-10
21808                                                                  63   2e-10
29581                                                                  63   2e-10
26560                                                                  63   3e-10
21418                                                                  62   5e-10
36002                                                                  61   1e-09
20152                                                                  61   1e-09
12786                                                                  60   1e-09
29590                                                                  45   2e-09
19094                                                                  50   5e-09
01756                                                                  58   7e-09
04591                                                                  58   8e-09
27546                                                                  56   3e-08
18663                                                                  55   5e-08
11185                                                                  55   5e-08
20655                                                                  55   7e-08
04138                                                                  55   8e-08
27274                                                                  53   2e-07
31120                                                                  53   3e-07
02638                                                                  52   6e-07
32000                                                                  51   9e-07
17300                                                                  51   9e-07
19301                                                                  51   9e-07
04852                                                                  51   9e-07
03508                                                                  50   1e-06
28157                                                                  50   2e-06
17722                                                                  49   5e-06
14116                                                                  49   7e-06
00715                                                                  48   8e-06
11780                                                                  47   2e-05
36481                                                                  47   2e-05
00394                                                                  46   3e-05
31789                                                                  45   4e-05
31489                                                                  44   1e-04
07291                                                                  44   1e-04
25019                                                                  44   1e-04
18481                                                                  42   6e-04
32957                                                                  41   0.001
07940                                                                  40   0.002
12672                                                                  40   0.002
01106                                                                  40   0.002
08294                                                                  40   0.003
18287                                                                  40   0.003
29360                                                                  40   0.003
11404                                                                  39   0.004
23319                                                                  39   0.006
18401                                                                  38   0.009
20513                                                                  37   0.015
37063                                                                  37   0.016
16350                                                                  37   0.020
18996                                                                  37   0.025
15549                                                                  36   0.040
07836                                                                  35   0.055
00638                                                                  35   0.056
16708                                                                  35   0.060
20160                                                                  35   0.096
37602                                                                  34   0.15 
32359                                                                  33   0.21 
35032                                                                  33   0.26 
26009                                                                  33   0.28 
20559                                                                  33   0.36 
17516                                                                  32   0.46 
33586                                                                  32   0.46 
21800                                                                  32   0.71 
03106                                                                  32   0.80 
13305                                                                  31   1.4  
03294                                                                  30   2.1  
28494                                                                  30   2.8  
17011                                                                  29   3.3  
14104                                                                  29   5.0  
32357                                                                  28   6.1  
32691                                                                  28   9.0  
>15910
          Length = 1361

 Score =  194 bits (492), Expect = 9e-50,   Method: Compositional matrix adjust.
 Identities = 100/207 (48%), Positives = 133/207 (64%)
 Frame = +2

Query: 96  ELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLA 155
           ELF+ IV R  Y+E DA+  I  IL  V + H  GVVHRDLKPENLL       + +KLA
Sbjct: 422 ELFDRIVTRGQYTEKDAARAISDILHGVQYIHANGVVHRDLKPENLLYECMTDDSKLKLA 601

Query: 156 DFGLAIEVEGEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDLWACGVILYILLVGYPPFWD 215
           DFGL+  +E E Q      GTPGY +PEVL+ D Y   VD+W+ GVI YILL GY PF+ 
Sbjct: 602 DFGLSRIIEPEVQM-STVCGTPGYCAPEVLKGDKYTPSVDMWSVGVIAYILLCGYEPFFA 778

Query: 216 EDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPSKRITAAEALKHPWISHRS 275
           E++  +Y++I  G Y F    W  ++  AKD++ K+L I+P KR+TA EAL+ PW+   +
Sbjct: 779 ENEFEMYRKIIKGEYKFDEEYWSEISENAKDVVRKLLVIDPKKRLTATEALRLPWVKGVA 958

Query: 276 TVASCMHRQETVDCLKKFNARRKLKGA 302
           T  + M  + T++ LK+FNARRKLK A
Sbjct: 959 TKTTNM--EITMNKLKEFNARRKLKCA 1033
>01392
          Length = 1806

 Score =  123 bits (308), Expect = 2e-28,   Method: Compositional matrix adjust.
 Identities = 74/191 (38%), Positives = 100/191 (52%), Gaps = 25/191 (13%)
 Frame = -1

Query: 106  YYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLA--IEV 163
            +  E +AS  ++ I  A+   H  G+ HRDLKPEN+L         VK+ DF LA  I  
Sbjct: 1803 HLCEREASLVVRHIARALDFLHSKGIAHRDLKPENILCEHLDDVVPVKICDFDLASGISC 1624

Query: 164  EGEQQA---WFGFAGTPGYLSPEVLR-----KDPYGKPVDLWACGVILYILLVGYPPFWD 215
            +G+           G+  Y++PEV+         Y K  DLW+ G+ILYI+L GYPPF+ 
Sbjct: 1623 DGDGTKTPELLTPVGSAEYMAPEVVDAWVGDSFSYDKRCDLWSLGIILYIMLCGYPPFYG 1444

Query: 216  ---ED------------QHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPSKRI 260
               ED            Q  L+  I+ G Y FPS EW +++  AKDLI  +L   P KR 
Sbjct: 1443 QCGEDCGWNRGEACHDCQDMLFNSIQDGHYKFPSQEWTSISSSAKDLIRHLLVREPRKRY 1264

Query: 261  TAAEALKHPWI 271
            +AA+ LKHPWI
Sbjct: 1263 SAADVLKHPWI 1231
>12721
          Length = 821

 Score =  122 bits (306), Expect = 3e-28,   Method: Compositional matrix adjust.
 Identities = 75/251 (29%), Positives = 134/251 (53%), Gaps = 4/251 (1%)
 Frame = +1

Query: 16  FEELGKGAFSVVRRCVKV-LAGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVR 74
           F ++G+G+  +V  C+     G++ A K ++ +K   R  + L  E  + R   HPNIV 
Sbjct: 103 FMKIGEGSTGIV--CIATSRDGRQMAVKKMDLRKQQRR--ELLFNEVVVMRDYHHPNIVE 270

Query: 75  LHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHR 134
           +++S       +++ + + GG L  DIV      E   +   +  L+A+   H  GV+HR
Sbjct: 271 MYNSYLVNDELWVVMEFMEGGAL-TDIVTNNRMDEVQIATVCRACLKALAFLHANGVIHR 447

Query: 135 DLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLSPEVLRKDPYGKPV 194
           D+K +++LL+   K   VKL DFG   +V  + Q      GTP +++PEV+ + PYG  V
Sbjct: 448 DIKSDSILLSHDGK---VKLXDFGFCAQVTQDLQKRKSLVGTPYWMAPEVISRLPYGPEV 618

Query: 195 DLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT---VTPEAKDLINKM 251
           D+W+ G+++  ++   PPF++E   +  ++I+    D P P+      ++P  +  I++M
Sbjct: 619 DIWSLGIMVMEMIDAEPPFFNEPPLQAMRRIR----DMPPPKLRNTHKISPRLQGFIDRM 786

Query: 252 LTINPSKRITA 262
           L  +P +R TA
Sbjct: 787 LVRDPHQRATA 819
>01707
          Length = 757

 Score =  107 bits (267), Expect = 1e-23,   Method: Compositional matrix adjust.
 Identities = 74/218 (33%), Positives = 106/218 (48%), Gaps = 4/218 (1%)
 Frame = +1

Query: 11  EEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREARICRLLKHP 70
           E+Y+   ++G+G++ VV +C      Q  A K     +      +   RE R+ + LKHP
Sbjct: 64  EKYEKIGKIGEGSYGVVFKCRNKETSQLVAIKKFVESEDDPLIKKIAMREIRMLKQLKHP 243

Query: 71  NIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMG 130
           N+VRL +    +   +L+FD V    L E         E      I Q L AV  CHQ  
Sbjct: 244 NLVRLIEVFRRKKRLHLVFDYVDHTLLNELDRYPRGLPEPMVKRIIYQTLLAVNFCHQYN 423

Query: 131 VVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLSPEVLRKDP- 189
            +HRD+KPEN+L+  +     VKL DFG A  + G    +  +  T  Y +PE+L  D  
Sbjct: 424 TIHRDVKPENILITRQ---GQVKLCDFGFARILTGPGDEYTDYVATRWYRAPELLVGDTQ 594

Query: 190 YGKPVDLWACGVILYILLVG---YPPFWDEDQHRLYQQ 224
           YG PVD+WA G +   LL G   +P   D DQ  L ++
Sbjct: 595 YGPPVDVWAIGCVFAELLTGQALWPGRSDVDQLHLIRK 708
>01060
          Length = 1800

 Score =  104 bits (259), Expect = 8e-23,   Method: Compositional matrix adjust.
 Identities = 82/298 (27%), Positives = 137/298 (45%), Gaps = 37/298 (12%)
 Frame = +1

Query: 16  FEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRL 75
           F+++G+G + VV +C     G++ A K I  +           RE  + R L+H NIV L
Sbjct: 88  FQKIGEGTYGVVYKCRHRATGRKLAMKKIRLRGSEDGVPSSAIREIAMLRELRHTNIVCL 267

Query: 76  HDSISEEGHHYLIFDLVTG-----------GELFEDIVAREYYSEADASHCIQQILEAVL 124
            D I E+   +L+F+ ++            G + +  + + Y         + QI+  + 
Sbjct: 268 EDVIMEDERLFLVFEFLSMDLKMYIDKFPEGVVLDRRLVKSY---------VFQIVTGIX 420

Query: 125 HCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLSPEV 184
            CHQ  +VHRDLKP+NLL+       A+K+ADFG+A       +A+     T  Y +PE+
Sbjct: 421 FCHQRRIVHRDLKPQNLLINHT---GAIKIADFGMARTFALPVRAYTHEVVTLWYRAPEI 591

Query: 185 LR-KDPYGKPVDLWACGVILYILLVGYPPF-WDEDQHRLYQQI---------------KA 227
           L     Y  PVD+W+ G I   +L+  P F  D +  +L++                 K 
Sbjct: 592 LMGASKYSTPVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIFRIIGTPTEQTWPEFHKL 771

Query: 228 GAYDFPSPEW------DTVT---PEAKDLINKMLTINPSKRITAAEALKHPWISHRST 276
            A++   P W      +T+T       DLI + L  +P++RI+  + L+H +  +  T
Sbjct: 772 PAFNGMFPLWKEGKLSETLTDLDSLGLDLIERTLKCDPAQRISCKKMLQHAYFLNVDT 945
>09606
          Length = 1300

 Score =  103 bits (256), Expect = 2e-22,   Method: Compositional matrix adjust.
 Identities = 75/286 (26%), Positives = 134/286 (46%), Gaps = 28/286 (9%)
 Frame = -3

Query: 11   EEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREARICRLLKHP 70
            E + L+EELGKG  S++ +  +       A   I   K       ++    R+   + HP
Sbjct: 1115 ENFVLYEELGKGEHSIIYKGRRKGTINFVAIHCIEKCK-----RPEVTNTVRMTHDISHP 951

Query: 71   NIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYY-SEADASHCIQQILEAVLHCHQM 129
            N+V+ H+      H +L+ +L TGG L  DI+A++++  E         ++  + + H +
Sbjct: 950  NVVQFHEWYETSNHLWLVVELCTGGSL-ADILAQDHHLPETSIRDFGIHLVTGLHYIHSL 774

Query: 130  GVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGE--QQAWFGFA------------- 174
            G++  DL+P  +LL +      +K ADFGL+ +VEGE  ++ +F FA             
Sbjct: 773  GILFHDLRPSKVLLDTS---GVLKFADFGLS-KVEGENLEELFFKFAEAGDQWNIQSAEE 606

Query: 175  --------GTPGYLSPEVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIK 226
                    G+P Y++PEV +        DLWA G + Y +  G+PPF  E       ++ 
Sbjct: 605  MMKQVPTSGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFSGHPPFLGETYDITKDKVL 426

Query: 227  AGAYDFPSPEWDTV----TPEAKDLINKMLTINPSKRITAAEALKH 268
               +  P  +   +    +PE  +L+  +L  + ++R++ A  +KH
Sbjct: 425  NKEFPLPKVKGSRLSAKPSPEFLNLLESLLQKDSTRRLSWASLVKH 288
>03240
          Length = 1683

 Score =  101 bits (252), Expect = 5e-22,   Method: Compositional matrix adjust.
 Identities = 79/287 (27%), Positives = 127/287 (44%), Gaps = 48/287 (16%)
 Frame = -3

Query: 13   YQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARD---HQKLEREARICRLLKH 69
            ++  + LG GAF  V  C K   G  YA K +    +  R+   H K ER+  I     +
Sbjct: 1285 FEKIKTLGVGAFGEVSLCRKNDTGMLYAMKTLRKSDVLKRNQVAHVKAERD--ILAEADN 1112

Query: 70   PNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQM 129
              +V+L+ S  +  + Y + D V GG+L   ++  E   E  A   + ++++A+   H+M
Sbjct: 1111 EWVVKLYYSFQDHNYLYFVMDYVPGGDLMGLLIRMEILDEPLARFYVAELVQAIESVHRM 932

Query: 130  GVVHRDLKPENLLLASKLKGAAVKLADFGL-----------------------AIEV--- 163
            G +HRD+KP+N+L+    +   +KL DFGL                       ++EV   
Sbjct: 931  GFIHRDIKPDNILID---RNGHIKLTDFGLCTGFRWTHNSKYYQRDGTHARQDSMEVKCQ 761

Query: 164  -----------------EGEQQAW-FGFAGTPGYLSPEVL-RKDPYGKPVDLWACGVILY 204
                             + EQ+       GTP Y++PEVL R   Y    D W+ GVIL+
Sbjct: 760  LDEQCQCEILKPLERRRKREQRCLAHSLVGTPNYIAPEVLSRLGGYTSVCDWWSVGVILF 581

Query: 205  ILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKM 251
             +LVG+PPF+         ++         P    ++  AKDLI ++
Sbjct: 580  EMLVGHPPFYANTPAETQYKVINWKDMLKIPRESNLSQPAKDLILRL 440
>30755
          Length = 1137

 Score =  100 bits (249), Expect = 1e-21,   Method: Compositional matrix adjust.
 Identities = 58/160 (36%), Positives = 86/160 (53%), Gaps = 5/160 (3%)
 Frame = +2

Query: 118 QILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTP 177
           +I+ A+ + H  G+++RDLK ENLLL    K   +K+ADFGL  E     +    F GTP
Sbjct: 56  EIISALGYLHSQGIIYRDLKLENLLLD---KDGHIKVADFGLCKEDITYGRTTKTFCGTP 226

Query: 178 GYLSPEVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEW 237
            YL+PEVL  + YG+ VD W  GV++Y ++ G  PF++ D   L+  I      FP    
Sbjct: 227 EYLAPEVLDDNDYGRAVDWWGTGVVMYEMICGRLPFYNRDHDVLFTLILVEDVKFPR--- 397

Query: 238 DTVTPEAKDLINKMLTINPSKRITAA-----EALKHPWIS 272
             +T EAK L++ +L  +P  R+        E   HP+ +
Sbjct: 398 -NITDEAKSLLSGLLAKDPRNRLGGGQDDVKEIQAHPFFA 514
>21079
          Length = 878

 Score = 92.4 bits (228), Expect(2) = 1e-21,   Method: Compositional matrix adjust.
 Identities = 52/145 (35%), Positives = 77/145 (53%), Gaps = 1/145 (0%)
 Frame = +1

Query: 69  HPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREY-YSEADASHCIQQILEAVLHCH 127
           HP ++ L D+        L+ + V  GELFE ++  ++  +E D  H ++QI   V + H
Sbjct: 1   HPKLLMLWDAFEAPRTMVLVMEFVGAGELFERVIRDDFVLTERDCVHFVRQICSGVGYMH 180

Query: 128 QMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLSPEVLRK 187
              ++H DLKPEN+L  S      +K+ DFGLA   +        F GTP +++PEV+  
Sbjct: 181 TQSILHLDLKPENVLCVSD-NSNQIKIIDFGLARFYKPGDSLQVLF-GTPEFIAPEVVNY 354

Query: 188 DPYGKPVDLWACGVILYILLVGYPP 212
           D      D+W+ GVI YILL G  P
Sbjct: 355 DEINFTTDMWSIGVICYILLSGLSP 429

 Score = 28.9 bits (63), Expect(2) = 1e-21,   Method: Compositional matrix adjust.
 Identities = 18/56 (32%), Positives = 27/56 (48%)
 Frame = +2

Query: 243 EAKDLINKMLTINPSKRITAAEALKHPWISHRSTVASCMHRQETVDCLKKFNARRK 298
            AKD I    +    KR+T  +  KH W++ +     C  ++   D L+ F ARRK
Sbjct: 518 NAKDFIGNC*SREKEKRMTIEQCDKHSWLAEQDQRIRC--KRLNTDRLRCFMARRK 679
>13592
          Length = 980

 Score = 98.6 bits (244), Expect = 5e-21,   Method: Compositional matrix adjust.
 Identities = 77/264 (29%), Positives = 126/264 (47%), Gaps = 11/264 (4%)
 Frame = +2

Query: 18  ELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHD 77
           ++G+G F  V   V    G+  A K I  +    R  + +  E +I   +KH N+VR + 
Sbjct: 5   KIGQGRFGKVYTAVNNNTGELMAMKEIAIQPGETRALKNVAEELKILEGIKHKNLVRYY- 181

Query: 78  SISEEGHHYLIF-DLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDL 136
            I       LIF +L + G L   +       EA +     Q+L  V   H+ G+VHRD+
Sbjct: 182 GIEVHREELLIFMELCSEGTLESLVELTGGLPEALSRRFTAQLLSGVAELHKHGIVHRDI 361

Query: 137 KPENLLLASKLKGAAVKLADFGLAIEVE------GEQQAWFGFAGTPGYLSPEVLRK--- 187
           K  N+ L       ++KL DFG A++++      GE Q   G+ GT  Y++PEV  K   
Sbjct: 362 KTANIFLVD--GSNSLKLGDFGSAVKIQAHTTVPGELQ---GYVGTQAYMAPEVFTKTNS 526

Query: 188 DPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFP-SPEWDTVTPEAKD 246
           D +G+  D+W+ G ++  +  G  P W +         K G  + P +PE  +++ E  D
Sbjct: 527 DGHGRLADIWSVGCVVVEMASGKRP-WAQFDSNFQIMFKVGMGEKPQAPE--SLSQEGHD 697

Query: 247 LINKMLTINPSKRITAAEALKHPW 270
            I+  L  +P +R++A E L+  +
Sbjct: 698 FIDHCLQHDPKQRLSAIELLEQNF 769
>17975
          Length = 449

 Score = 97.8 bits (242), Expect = 9e-21,   Method: Composition-based stats.
 Identities = 53/138 (38%), Positives = 82/138 (59%), Gaps = 1/138 (0%)
 Frame = +3

Query: 24  FSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEG 83
           F+VV+    V  G++ A K+I+  KL       L +E R  +L++HPN+VRL++ I  + 
Sbjct: 6   FAVVKLARHVFTGEKVAVKVIDKTKLDEVSRSHLFQEVRCMKLVQHPNVVRLYEVIDTQT 185

Query: 84  HHYLIFDLVTGGELFEDIVARE-YYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLL 142
             YLI +L  GG++++ I+       E  A    +QI+EA+ +CH++ VVHRDLKPEN++
Sbjct: 186 KLYLILELGDGGDMYDYIMRHSGGLEEKLAKRYFRQIVEAISYCHKLHVVHRDLKPENVV 365

Query: 143 LASKLKGAAVKLADFGLA 160
                K   VKL DFG +
Sbjct: 366 FFE--KPGLVKLTDFGFS 413
>18484
          Length = 635

 Score = 96.7 bits (239), Expect = 2e-20,   Method: Compositional matrix adjust.
 Identities = 53/154 (34%), Positives = 82/154 (53%)
 Frame = +1

Query: 107 YSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGE 166
           + E  A+    +I   +   H  G+++RDLK +N++L S+     +K+ADFG+  E    
Sbjct: 34  FKEPVAAFYAAEIAVGLFFLHDQGIIYRDLKLDNVMLDSE---GHIKIADFGMCKEGMTG 204

Query: 167 QQAWFGFAGTPGYLSPEVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIK 226
                 F GTP Y++PE++   PY K VD WA GV+L+ +L G PPF  ED+  L+  I 
Sbjct: 205 DATTRTFCGTPDYIAPEIVLYQPYSKSVDWWAYGVLLFEMLAGQPPFDGEDEDELFSSIT 384

Query: 227 AGAYDFPSPEWDTVTPEAKDLINKMLTINPSKRI 260
                +P      ++ EA  L   +L  NP+KR+
Sbjct: 385 DHNVSYPK----AMSREAVSLCKGLLMKNPTKRL 474
>14420
          Length = 528

 Score = 95.5 bits (236), Expect = 4e-20,   Method: Compositional matrix adjust.
 Identities = 55/176 (31%), Positives = 93/176 (52%), Gaps = 1/176 (0%)
 Frame = +2

Query: 46  TKKLSARDHQKLE-REARICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAR 104
           T  LS +  ++L   E  + R  ++PNIV   DS       +++ + + GG L  D+V  
Sbjct: 5   TMNLSQQPKKELIINEILVMRENQNPNIVNYLDSYLVGEELWVVMEFLAGGSL-TDVVTE 181

Query: 105 EYYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVE 164
               E   +   ++ L+A+   H+  V+HRD+K +N+LL       +VKL DFG   ++ 
Sbjct: 182 TCMDEGQIAAVCRECLQALEFLHENQVIHRDIKSDNILLGMD---GSVKLTDFGFCAQLS 352

Query: 165 GEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHR 220
            EQ       GTP +++PEV+ +  YG  VD+W+ GV+   ++ G PP+ +E+  R
Sbjct: 353 PEQSKRSTMVGTPYWMAPEVVTRKQYGPTVDIWSLGVMCIEMIEGEPPYLNENPLR 520
>26711
          Length = 405

 Score = 93.6 bits (231), Expect = 2e-19,   Method: Composition-based stats.
 Identities = 51/134 (38%), Positives = 75/134 (55%), Gaps = 1/134 (0%)
 Frame = -2

Query: 116 IQQILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAG 175
           ++Q+L+ + H H  GVVH DLKP NLLL+   K  +V+L DFGLA ++   Q+ +    G
Sbjct: 398 VKQVLDILQHVHAQGVVHMDLKPSNLLLSGD-KLDSVQLIDFGLARKLYPPQETFLNH-G 225

Query: 176 TPGYLSPEVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFP-S 234
           TPG+ SPE L   P     D+W  GV+ YILL G  PF  +      ++ +   + F   
Sbjct: 224 TPGFTSPEALDVKPISTASDVWGVGVLAYILLSGQSPFQADSATESLKKTQTCDWSFDVC 45

Query: 235 PEWDTVTPEAKDLI 248
           P +  ++ +AKD I
Sbjct: 44  PSFSNMSQDAKDFI 3
>14126
          Length = 1265

 Score = 92.4 bits (228), Expect = 4e-19,   Method: Compositional matrix adjust.
 Identities = 89/304 (29%), Positives = 135/304 (44%), Gaps = 43/304 (14%)
 Frame = +3

Query: 11  EEYQLFEELGKGAFSVVRRCVKVLAGQEYAA-KIINTKKLSARDHQKLEREARICRLLK- 68
           ++Y+    +G GA+  V +   +    E+ A K I              RE  + + L+ 
Sbjct: 189 QKYEEVAVIGNGAYGTVYKARDLRNQGEFVAMKRIRLNNTEEGMPMMAIREISMLKQLEQ 368

Query: 69  --HPNIVRL----HDSISE-EGHHYLIFDLVTGGELFEDIVAREYYSEADA--------S 113
             HPN+VRL    H++I++ E    L+F+ +       D+    Y ++  +         
Sbjct: 369 YEHPNVVRLLDVSHNTITDREIRLNLVFEYIE-----HDLAT--YLAKCPSPGLGPDRIK 527

Query: 114 HCIQQILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGF 173
             + Q+L  V   H   +VHRDLKP+NLL++   K   +KLADFGLA  +     A    
Sbjct: 528 DLMLQLLNGVDFLHSNRIVHRDLKPQNLLIS---KDGRLKLADFGLA-RIYSFHMALTTV 695

Query: 174 AGTPGYLSPEVLRKDPYGKPVDLWACGVILYIL---------------------LVGYPP 212
             T  Y SPEVL +  YG  VD+W+CG I   L                     ++G PP
Sbjct: 696 VVTLWYRSPEVLMQAEYGTSVDIWSCGCIFAELFTRRALFKGSSEFDQLKKIFEVIGLPP 875

Query: 213 F--WDE--DQHR-LYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPSKRITAAEALK 267
              W E    HR  ++           PE D   P+AKDL+ KML     +RI++ E+L 
Sbjct: 876 AGDWPEGVSVHRNSFRPTPPVPLQTLVPEMD---PQAKDLMEKMLVFKSGRRISSRESLL 1046

Query: 268 HPWI 271
           HP++
Sbjct: 1047HPYL 1058
>00300
          Length = 2318

 Score = 88.2 bits (217), Expect = 6e-18,   Method: Compositional matrix adjust.
 Identities = 71/277 (25%), Positives = 130/277 (46%), Gaps = 10/277 (3%)
 Frame = -1

Query: 4    ITCTRFTEEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLER---E 60
            I   R    +Q   ++G+G F  V   V +  G+  A K +   K    D Q+L     E
Sbjct: 1679 INVRRVNFRWQRGNKIGEGQFGKVYTAVNMSTGELMALKEM---KFQPNDLQQLREMCDE 1509

Query: 61   ARICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQIL 120
             +I   ++H N+V+ +     +    +  +    G + E   A+    E       ++I+
Sbjct: 1508 IKIFEGIQHENLVKYYGVEVHKDEMLMFMEYCDTGTIEE--AAKMGLPEYLIRRYTREIV 1335

Query: 121  EAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQA---WFGFAGTP 177
             AV H H+  +VHRD+K  N+ L S      VKL DFG +++++        +    GT 
Sbjct: 1334 LAVNHLHENSIVHRDIKGANIFLTSN---GHVKLGDFGCSVKLKSHTTMPGEFHNLVGTT 1164

Query: 178  GYLSPEVLRKDP---YGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQI-KAGAYDFP 233
             Y++PEV  ++    YG+  D+W+ G ++  +  G  P+ D D +  YQ + K G    P
Sbjct: 1163 AYMAPEVFTQNDQGGYGRAADIWSLGCVVIEMATGKRPWHDLDNN--YQIMYKVGIGHKP 990

Query: 234  SPEWDTVTPEAKDLINKMLTINPSKRITAAEALKHPW 270
            +   D+++ E K  ++ ++  +P++R  A++ L H +
Sbjct: 989  AVP-DSLSVEGKHFLDLIMCHDPAQRALASQLLDHTF 882
>21433
          Length = 590

 Score = 74.3 bits (181), Expect(2) = 1e-16,   Method: Compositional matrix adjust.
 Identities = 48/142 (33%), Positives = 70/142 (49%), Gaps = 5/142 (3%)
 Frame = +2

Query: 116 IQQILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAG 175
           I Q+  A+ +CH   V+HRD+KPEN           +K+ADFG ++     ++      G
Sbjct: 185 IYQLSSALEYCHYRKVIHRDIKPEN---LLLGLKGDLKIADFGWSVHAPSSRRT--TMCG 349

Query: 176 TPGYLSPEVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSP 235
           T  YL PE++    + + VDLW+ GV+ Y  LVG PP          +          SP
Sbjct: 350 TLDYLPPEMVEGKTHDENVDLWSLGVLCYEFLVGTPPL---------RPSPTRPPTPASP 502

Query: 236 EWDT-----VTPEAKDLINKML 252
            W +     VTP A+DLI+K+L
Sbjct: 503 RWTSGSPSIVTPGARDLISKLL 568

 Score = 30.0 bits (66), Expect(2) = 1e-16,   Method: Compositional matrix adjust.
 Identities = 15/47 (31%), Positives = 26/47 (55%)
 Frame = +3

Query: 55  QKLEREARICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDI 101
            +L RE  I   L+H NI+R+     ++   YLI +    GEL++++
Sbjct: 3   HQLRREIEIQSHLRHDNILRMFGYFHDKTRVYLILEFAPKGELYKEL 143
>13212
          Length = 1067

 Score = 79.3 bits (194), Expect = 3e-15,   Method: Compositional matrix adjust.
 Identities = 59/173 (34%), Positives = 88/173 (50%), Gaps = 9/173 (5%)
 Frame = -1

Query: 108 SEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQ 167
           +EA   +   ++  A+   H+  V+HRD+K  N+LL        VKLADFG++ +    Q
Sbjct: 986 TEAQICYVCHEMCMALDFLHRHHVIHRDIKAGNVLLTI---DGEVKLADFGVSAKNTQTQ 816

Query: 168 QAWFGFAGTPGYLSPEV-----LRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLY 222
           Q    F GTP +++PEV     L+  PY    D+W+ GV L       PP  +++ H + 
Sbjct: 815 QKRDTFIGTPYWMAPEVVLCETLKDTPYDFKADIWSLGVTLIEFAQIEPP--NKEMHPMR 642

Query: 223 QQIKAGAYDFPSPE----WDTVTPEAKDLINKMLTINPSKRITAAEALKHPWI 271
             IK    D P+ E    W  +    KD I K L  +P+ R TAAE L+HP++
Sbjct: 641 VLIKIHKSDPPTLEKPKKWTKL---FKDFIAKCLVKDPNLRPTAAELLEHPFM 492
>13066
          Length = 551

 Score = 76.3 bits (186), Expect = 3e-14,   Method: Compositional matrix adjust.
 Identities = 53/166 (31%), Positives = 78/166 (46%), Gaps = 5/166 (3%)
 Frame = +3

Query: 40  AAKIINTKKLSARDHQKL-EREARICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGGELF 98
           A KII+ +K      +K   RE  +   L HP I+++H  +     +++       G+L 
Sbjct: 63  ACKIIDKEKAPVDFVEKFFPRELDLLTKLDHPYIIQIHSILQRXPKNFIFMRFAERGDLL 242

Query: 99  EDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFG 158
             I    +  E  A     Q+  A+ + H   V HRDLK EN+LL+S      VKLADFG
Sbjct: 243 TYIQEVGFVKEKQAKIWFYQMTTALNYLHSYDVAHRDLKCENILLSSHFN---VKLADFG 413

Query: 159 LA---IEVEGEQQAWFGFAGTPGYLSPEVLRKDPYG-KPVDLWACG 200
            A   I   GE+     + G+  Y +PE++   PY  K  D W+ G
Sbjct: 414 FACACITESGEKYMSRTYCGSAAYAAPEIVYGAPYAPKVADAWSLG 551
>09007
          Length = 1440

 Score = 70.9 bits (172), Expect = 1e-12,   Method: Compositional matrix adjust.
 Identities = 59/226 (26%), Positives = 105/226 (46%), Gaps = 13/226 (5%)
 Frame = -1

Query: 15  LFEELGKGAFSVVRRCVKVLAGQE---YAAKIINTKKLSARDHQKLEREARICRLLKHPN 71
           L + LG+G F  VR+ +      E    A K ++  K+  +D Q+  +E  I ++L H N
Sbjct: 867 LSKSLGQGHFGTVRQAIWTAESGEKVQVAVKCLSKDKIH-KDGQEFLKETAIMQMLDHEN 691

Query: 72  IVRLHDSISEEGHH-YLIFDLVTGGELFE---DIVAREYYSEADASHCIQQILEAVLHCH 127
           IVR++  + + G    L+ +L     L E   ++ AR  +S        QQ+ + + +  
Sbjct: 690 IVRVYGVVMDNGADIMLVTELAPMRSLLECVKEVSARVDFSVPRLCDFSQQVCDGMSYLE 511

Query: 128 QMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEG-----EQQAWFGFAGTPGYLSP 182
              +VHRDL   N+LL SK K   VK++D G++  +       + Q          + +P
Sbjct: 510 SKRLVHRDLAARNILLFSKSK---VKISDVGVSGALGAGKEYYQSQQTIHLQNAVAWCAP 340

Query: 183 EVLRKDPYGKPVDLWACGVILYILLV-GYPPFWDEDQHRLYQQIKA 227
           E  R   +    D+WA GV+L+     G+ P+   +  ++ + + A
Sbjct: 339 ESFRNLCFSSASDVWAFGVLLWEFFTHGFQPWAGLNGQQIMEAVDA 202
>01966
          Length = 1735

 Score = 70.9 bits (172), Expect = 1e-12,   Method: Compositional matrix adjust.
 Identities = 57/190 (30%), Positives = 86/190 (45%), Gaps = 14/190 (7%)
 Frame = -1

Query: 27   VRR---CVKVLAGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEG 83
            VRR   C     G++ A K I  +           RE  + R L+H NIV L D I E+ 
Sbjct: 1672 VRRGL*CRHRATGRKLAMKKIRLRGSEDGVPSSAIREIAMLRELRHTNIVCLEDVIMEDE 1493

Query: 84   HHYLIFDLVTG-----------GELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVV 132
              +L+F+ ++            G + +  + + Y         + QI+  +  CHQ  +V
Sbjct: 1492 RLFLVFEFLSMDLKMYIDKFPEGVVLDRRLVKSY---------VFQIVTGINFCHQRRIV 1340

Query: 133  HRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLSPEVLRKDPYGK 192
            HRDLKP+NLL+       A+K+ADFG+A       +A+     T  Y +PE+L   P   
Sbjct: 1339 HRDLKPQNLLINHT---GAIKIADFGMARTFALPVRAYTHEVVTLWYRAPEIL-MGPQST 1172

Query: 193  PVDLWACGVI 202
            P   W CG +
Sbjct: 1171 P-PXWTCGAL 1145

 Score = 31.6 bits (70), Expect = 0.71,   Method: Compositional matrix adjust.
 Identities = 32/125 (25%), Positives = 53/125 (42%), Gaps = 25/125 (20%)
 Frame = -3

Query: 177  PGYLSPEVLRKDPYGKPVDLWACGVILYILLVGYPPF-WDEDQHRLYQQI---------- 225
            PG   P    K  Y  PVD+W+ G I   +L+  P F  D +  +L++            
Sbjct: 1208 PGPRDPHGASK--YSTPVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIFRIIGTPTEQT 1035

Query: 226  -----KAGAYDFPSPEW------DTVT---PEAKDLINKMLTINPSKRITAAEALKHPWI 271
                 K  A++   P W      +T+T       DLI + L  +P++RI+  + L+H + 
Sbjct: 1034 WPEFHKLPAFNGMFPLWKEGKLSETLTDLDSLGLDLIERTLKCDPAQRISCKKMLQHAYF 855

Query: 272  SHRST 276
             +  T
Sbjct: 854  LNVDT 840
>31885
          Length = 529

 Score = 70.1 bits (170), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 46/152 (30%), Positives = 76/152 (50%), Gaps = 5/152 (3%)
 Frame = -2

Query: 67  LKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHC 126
           L HP +V L  +  +E   +++ DL  GG+L   +     + E      + Q+   + + 
Sbjct: 501 LDHPFLVNLWYAFQDEEDLFMVVDLFLGGDLRYHMQQEVSFREDCVKFYLCQLALVLDYL 322

Query: 127 HQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLSPEVL- 185
               +VHRD+KP+N+LL  +       + DF +A ++E ++ A    +GT  Y++PEV  
Sbjct: 321 RSQKIVHRDIKPDNILLDEQ---GHCHVTDFNIATQLEDDELA-TSTSGTRPYMAPEVYG 154

Query: 186 ----RKDPYGKPVDLWACGVILYILLVGYPPF 213
                +  YG PVD W+ GV L+ LL    PF
Sbjct: 153 VAINERRGYGFPVDWWSLGVSLFELLKKRRPF 58
>00392
          Length = 668

 Score = 69.3 bits (168), Expect = 3e-12,   Method: Compositional matrix adjust.
 Identities = 55/214 (25%), Positives = 104/214 (48%), Gaps = 8/214 (3%)
 Frame = +3

Query: 44  INTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGHH-----YLIFDLVTGGELF 98
           +  KK +  + Q+ + EA + + L+HPNIVR  D   E  H       L+ +L+T G L 
Sbjct: 33  LQDKKWNKAERQRFKEEAEMLKELQHPNIVRFFDYWEEHNHRNRKVIILVTELMTSGTLK 212

Query: 99  EDIVAREYYSEADASHCIQQILEAV--LHCHQMGVVHRDLKPENLLLASKLKGAAVKLAD 156
             +   +  +     +  +Q+L+ +  LH     V+HRDLK +N+ +       +VK+ D
Sbjct: 213 TYLKRFKKPNVKILKNWCRQVLKGLYFLHTRTPPVIHRDLKCDNIFITG--PTGSVKIGD 386

Query: 157 FGLAIEVEGEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDLWACGVILYILLVGYPPFWD- 215
            GLA      Q       GTP +++PE + ++ Y + VD++A G+ +  +     P+ + 
Sbjct: 387 LGLA--TLKNQSFAKSVIGTPEFMAPE-MYEEHYDEAVDVYAFGMCMLEMASSEYPYSEC 557

Query: 216 EDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLIN 249
            +  ++Y+++ +G    P         E +D+I+
Sbjct: 558 SNAAQIYKRVTSGV--LPEALDKVAITEIRDIIH 653
>28638
          Length = 1458

 Score = 63.5 bits (153), Expect(2) = 4e-12,   Method: Compositional matrix adjust.
 Identities = 37/99 (37%), Positives = 57/99 (57%), Gaps = 2/99 (2%)
 Frame = -1

Query: 117 QQILEAVLHCH--QMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFA 174
           QQ+  A+L     +M ++H DLKPEN+LL +  K +A+K+ DFG + ++    Q  + + 
Sbjct: 816 QQLCTALLFLATPEMNIIHCDLKPENILLCNP-KRSAIKIVDFGSSCQLG---QRIYQYI 649

Query: 175 GTPGYLSPEVLRKDPYGKPVDLWACGVILYILLVGYPPF 213
            +  Y SPEVL   PY   +D+W+ G IL  +  G PP 
Sbjct: 648 QSRFYRSPEVLLGVPYDLAIDMWSLGCILVEMHTGEPPL 532

 Score = 25.4 bits (54), Expect(2) = 4e-12,   Method: Compositional matrix adjust.
 Identities = 22/92 (23%), Positives = 42/92 (45%), Gaps = 6/92 (6%)
 Frame = -3

Query: 8    RFTEEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREARICRLL 67
            ++ + Y++   +GKG+F  V +       ++ A KII  KK       + + E ++  L+
Sbjct: 1156 KWLDRYEIDSLIGKGSFGQVVKAYDHGDQEQVAIKIIKNKKPFL---NQAQIEVKLLELM 986

Query: 68   KHPN------IVRLHDSISEEGHHYLIFDLVT 93
               +      IVRL        H  L+F+L++
Sbjct: 985  NRHDADNXYYIVRLKRHFMFRNHLCLVFELLS 890
>00486
          Length = 797

 Score = 68.2 bits (165), Expect = 8e-12,   Method: Compositional matrix adjust.
 Identities = 35/102 (34%), Positives = 56/102 (54%)
 Frame = -2

Query: 173 FAGTPGYLSPEVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDF 232
           F GT  Y++PE+L +  +GK VD W+ G ++Y +L G PPF  E++ +   +I  G  + 
Sbjct: 778 FCGTIEYMAPEILTRTGHGKAVDWWSLGALMYDMLTGSPPFTAENRKKTIDKILKGKLNL 599

Query: 233 PSPEWDTVTPEAKDLINKMLTINPSKRITAAEALKHPWISHR 274
           P      +T EA+ LI K+L  NP++R+        P   H+
Sbjct: 598 PP----YLTNEARGLIKKLLRKNPAERLGGGHDDSGPIKDHQ 485
>27405
          Length = 532

 Score = 67.8 bits (164), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 49/170 (28%), Positives = 79/170 (46%), Gaps = 5/170 (2%)
 Frame = -3

Query: 23  AFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREARICRLL-----KHPNIVRLHD 77
            F  V  C K   G+ YA K ++ K++  +  + L    RI   L       P IV +  
Sbjct: 530 GFGEVYGCRKADTGKMYAMKCLDKKRIKMKGGETLALNERIMLSLVSTGEGSPFIVCMTY 351

Query: 78  SISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLK 137
           +         I DL+ GG+L   +     ++E +      +++  + H H   VV+RDLK
Sbjct: 350 AFQTPEKLCFILDLMNGGDLHYHLSQHGVFTEKEVRFYAAEVMLGLEHMHSRFVVYRDLK 171

Query: 138 PENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLSPEVLRK 187
           P N+LL    +   V+++D GLA +    ++      GT GY++PEVL K
Sbjct: 170 PANILLD---ENGHVRISDLGLACDF--SKKKPHASVGTHGYMAPEVLMK 36
>19761
          Length = 473

 Score = 67.4 bits (163), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 44/130 (33%), Positives = 65/130 (50%)
 Frame = -3

Query: 124 LHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLSPE 183
           +H H   ++HRDLKP+N+ +  K     V+L D GLA ++ G         GT  YLSPE
Sbjct: 375 MHTHTPVILHRDLKPQNIYVTEK---GDVRLGDLGLARKLTGPADFATSQVGTIMYLSPE 205

Query: 184 VLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPE 243
           +L + PY    D+W+ G + Y  + G     +     L  Q+  G    P P  D  + E
Sbjct: 204 ILSQQPYNSKSDIWSLGCVFYD-ITGKKGSDEMGVMFLLVQVMGGR-KLPLP--DHYSQE 37

Query: 244 AKDLINKMLT 253
            +D I++MLT
Sbjct: 36  FRDTISRMLT 7
>01718
          Length = 959

 Score = 66.6 bits (161), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 54/192 (28%), Positives = 96/192 (50%), Gaps = 5/192 (2%)
 Frame = +3

Query: 17  EELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLH 76
           E++G G FS V +    + GQ  A K+ NT  +++  H  L RE ++   L+H NI+R  
Sbjct: 165 EKIGAGFFSEVFKVTHRITGQVMALKM-NT--MTSNRHNML-REVQLLNRLQHANILRFM 332

Query: 77  DSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQIL---EAVLHCHQMGVVH 133
                EG  + + + +  G L + +  ++   E   +  IQ  L     + + H    +H
Sbjct: 333 GVCVHEGQLHALTEYIPSGNLEQLLEKKD--EELPWTQRIQLTLGLARGLDYLHSTRFIH 506

Query: 134 RDLKPENLLLASKLK-GAAVKLADFGLAIEV-EGEQQAWFGFAGTPGYLSPEVLRKDPYG 191
           RDL  +N+L+  +   G    +ADFGLA ++ +   +      G+P +++PEVL    Y 
Sbjct: 507 RDLTSKNILIRREDNHGYHAVIADFGLATKIPDPLDKEKLPTVGSPYWMAPEVLNGHFYN 686

Query: 192 KPVDLWACGVIL 203
           +  DL++ G+I+
Sbjct: 687 ERADLFSVGIIM 722
>38560
          Length = 479

 Score = 65.5 bits (158), Expect = 5e-11,   Method: Compositional matrix adjust.
 Identities = 44/121 (36%), Positives = 61/121 (50%), Gaps = 5/121 (4%)
 Frame = -3

Query: 175 GTPGYLSPEVLRKDPY-GKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFP 233
           G+P Y +PE++    Y G   D+W+ GV+LY LL GY PF DE    L Q+ +    +  
Sbjct: 399 GSPAYAAPELISGLEYLGSEADIWSMGVLLYALLCGYLPFDDEKXSHL*QKNQKRKDEV- 223

Query: 234 SPEWDTVTPEAKDLINKMLTINPSKRITAAEALKHPWISHRSTV----ASCMHRQETVDC 289
            PEW  ++ +   L+  ML  +PS RIT    L H W++    V    AS   R    DC
Sbjct: 222 -PEW--LSEDTTKLLEGMLQTDPSHRITIRRLLDHHWLNQGFNVPVEWASKYKRTLDEDC 52

Query: 290 L 290
           L
Sbjct: 51  L 49
>18921
          Length = 697

 Score = 64.7 bits (156), Expect = 8e-11,   Method: Compositional matrix adjust.
 Identities = 47/201 (23%), Positives = 95/201 (47%), Gaps = 1/201 (0%)
 Frame = +2

Query: 13  YQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNI 72
           + +  +LG+G++  V + +    GQ  A K +        D Q++ +E  I +      I
Sbjct: 35  FDILGKLGEGSYGSVFKSLHKETGQVLAIKQVPVDT----DLQEIIKEISIMQQCDSKYI 202

Query: 73  VRLHDSISEEGHHYLIFDLVTGGELFEDIVAR-EYYSEADASHCIQQILEAVLHCHQMGV 131
           V+ + S  +    +++ +    G + + +  R +   E + +  +   L+ + + H    
Sbjct: 203 VKYYGSYFKNTDLWIVMEYCGAGSVSDIMRLRNKTLVEREIATILYYTLKGLXYLHSRRK 382

Query: 132 VHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLSPEVLRKDPYG 191
           +HRD+K  N+LL ++      KLADFG+A ++           GTP +++PEV+++  Y 
Sbjct: 383 IHRDIKAGNILLNNE---GHAKLADFGVAGQLTDTMAKRNTVIGTPYWMAPEVIQEIGYD 553

Query: 192 KPVDLWACGVILYILLVGYPP 212
              D+W+ G+    +  G PP
Sbjct: 554 CVADIWSLGITALEMAEGKPP 616
>06405
          Length = 1965

 Score = 63.5 bits (153), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 56/221 (25%), Positives = 96/221 (43%), Gaps = 4/221 (1%)
 Frame = +1

Query: 12  EYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPN 71
           E  +   LG G +  V   +     +  A K +    ++  D      EA I + +KHPN
Sbjct: 262 EIAMKHRLGGGQYGDVYEAMWKRYNKIVAVKTLKEDTMALND---FLEEAAIMKEMKHPN 432

Query: 72  IVRLHDSISEEGHHYLIFDLVTGGELFEDIVA--REYYSEADASHCIQQILEAVLHCHQM 129
           +V+L    + E   Y++ + +  G L + + +  RE        +   QI   + +    
Sbjct: 433 LVQLLGVCTREPPFYIVTEFMPHGNLLDYLRSSTREENGPTALMYMATQIASGMAYLETK 612

Query: 130 GVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQ-QAWFGFAGTPGYLSPEVLRKD 188
             +HRDL   N L+A       VK+ADFGLA  ++ +   A  G      + +PE L  +
Sbjct: 613 NFIHRDLAARNCLVAD---SNMVKVADFGLARLMKDDTYTAHIGAKFPIKWTAPEGLAFN 783

Query: 189 PYGKPVDLWACGVILYILLV-GYPPFWDEDQHRLYQQIKAG 228
            +    D+WA GV+L+ L   G  P+   +   +Y  ++ G
Sbjct: 784 RFSTRSDIWAFGVLLWELATYGMSPYPGVELTEVYHLLERG 906
>21808
          Length = 1011

 Score = 63.2 bits (152), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 51/195 (26%), Positives = 91/195 (46%), Gaps = 3/195 (1%)
 Frame = +1

Query: 44  INTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVA 103
           I T K    D +    EA+I + L+HP +++L+   +++   ++I +L+  G L E +  
Sbjct: 34  IKTLKSGTMDPKDFLAEAQIMKKLRHPKLIQLYAVCTQDDPIFIITELMKNGSLLEFLQG 213

Query: 104 REYYSEADASHCI-QQILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIE 162
           +    +  A   I  QI   + +      +HRDL   N+L++       VK+ADFGLA  
Sbjct: 214 KGRVLKLPALIDIGAQIACGMAYLESQNYIHRDLAARNILVSDN---NTVKIADFGLARV 384

Query: 163 V-EGEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDLWACGVILY-ILLVGYPPFWDEDQHR 220
           + E E +A  G      + +PE    + +    D+W+ G++L   +  G  P+       
Sbjct: 385 IKEDEYEARVGARFPIKWTAPEAANYNRFTIKSDVWSFGILLTETVTYGRVPYPGMTNAE 564

Query: 221 LYQQIKAGAYDFPSP 235
           +  Q++ G Y  P P
Sbjct: 565 VLHQVEHG-YRMPCP 606
>29581
          Length = 1278

 Score = 63.2 bits (152), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 65/243 (26%), Positives = 106/243 (43%), Gaps = 35/243 (14%)
 Frame = -2

Query: 67   LKHPNIVRLHDSISEEGHHYLIF-------DLVTGGELFEDIVAREYYSEADASHCIQQI 119
            L+H NIV+L + +  +    L         DL +   L +++ A   +SE+     + Q+
Sbjct: 1184 LRHQNIVQLQEVVVGKSLDSLFLVMEYCEQDLAS---LLDNMPAP--FSESQVKCIVLQL 1020

Query: 120  LEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGY 179
            L+ + + H+  ++HRDLK  NLL+  K     VK+ADFGLA      Q+       T  Y
Sbjct: 1019 LKGLRYLHEAFIIHRDLKVSNLLMTDK---GCVKIADFGLARNYGKPQKPMTPKVVTLWY 849

Query: 180  LSPEVL-RKDPYGKPVDLWACGVILYILLVGYPPFW----DEDQHRLYQQ--------IK 226
             +PE+L     +   +D+W+ G IL  LL G+ P      D  Q  L  +        I 
Sbjct: 848  RAPELLFGSKTHSTAIDMWSAGCILGELL-GHKPLMPGRSDLQQIELIMELLGTPNDTIW 672

Query: 227  AGAYDFPSPEWDTVTPEAKD---------------LINKMLTINPSKRITAAEALKHPWI 271
             G    P+ E  T+  +  +               L+N +   +P KR TA + L+H + 
Sbjct: 671  PGFSQLPAFEQFTLKKQPYNNLRHTFPWLSESGIRLLNGLFMYHPQKRATAEDCLEHSYF 492

Query: 272  SHR 274
              +
Sbjct: 491  KEQ 483
>26560
          Length = 398

 Score = 63.2 bits (152), Expect = 3e-10,   Method: Composition-based stats.
 Identities = 38/113 (33%), Positives = 61/113 (53%), Gaps = 1/113 (0%)
 Frame = -1

Query: 107 YSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGE 166
           ++E +      +++  + H H   VV+RDLKP N+LL    +   V+++D GLA +   +
Sbjct: 365 FTEKEVRFYAAEVMLGLEHMHSRFVVYRDLKPANILLD---ENGHVRISDLGLACDFSKK 195

Query: 167 QQAWFGFAGTPGYLSPEVLRK-DPYGKPVDLWACGVILYILLVGYPPFWDEDQ 218
           +       GT GY++PEVL K   Y    D ++ G +LY LL G+ PF   +Q
Sbjct: 194 RP--HASVGTHGYMAPEVLMKGQSYDSSADWFSFGCMLYKLLKGHSPFRQHNQ 42
>21418
          Length = 831

 Score = 62.0 bits (149), Expect = 5e-10,   Method: Compositional matrix adjust.
 Identities = 25/57 (43%), Positives = 38/57 (66%)
 Frame = +2

Query: 221 LYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPSKRITAAEALKHPWISHRSTV 277
           + ++I++G YDFP PEW  V+  AKDLI  ML ++PSKR+   + L++ WI+    V
Sbjct: 2   MKKRIRSGQYDFPDPEWTNVSQAAKDLIKGMLNVDPSKRLCIEDVLRNKWIAQYDAV 172
>36002
          Length = 253

 Score = 60.8 bits (146), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 26/56 (46%), Positives = 36/56 (64%)
 Frame = +1

Query: 218 QHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPSKRITAAEALKHPWISH 273
           Q  L+ +I+ G Y FPS EW  ++  AKDLI  +L   P KR +AA+ LKHPW+ +
Sbjct: 49  QELLFNRIQDGNYFFPSMEWSAISSSAKDLIRHLLVREPRKRYSAADVLKHPWVCN 216
>20152
          Length = 445

 Score = 60.8 bits (146), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 34/92 (36%), Positives = 48/92 (52%), Gaps = 1/92 (1%)
 Frame = +1

Query: 182 PEVLRKDPYGKP-VDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTV 240
           PE+L  D Y  P VD+W+ GVILY+L+VG  PF + +       I    Y  P      +
Sbjct: 1   PEILLGDSYDAPAVDVWSLGVILYMLVVGEAPFQEANDSETLTMIMDCRYQIPP----HI 168

Query: 241 TPEAKDLINKMLTINPSKRITAAEALKHPWIS 272
           + + +DLI KML   P  R +    L HPW++
Sbjct: 169 SHKCQDLIEKMLQREPVDRASLPHILAHPWLN 264
>12786
          Length = 460

 Score = 60.5 bits (145), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 38/119 (31%), Positives = 57/119 (47%), Gaps = 22/119 (18%)
 Frame = -3

Query: 117 QQILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWF--GFA 174
           +++L AV   H  GV+H DLKP N +L +      +KL DFG+A  ++ ++ +       
Sbjct: 389 REMLRAVKALHNEGVIHSDLKPANFMLVA----GNLKLIDFGIANTLQQDKTSVLKDSRV 222

Query: 175 GTPGYLSPEVL-----------------RKDP---YGKPVDLWACGVILYILLVGYPPF 213
           GTP Y+SPE +                 R  P    G   D+W+ G ILY ++ G  PF
Sbjct: 221 GTPSYMSPEAIMAACDDSADDSMEEDGHRTKPKYKVGVRSDVWSLGCILYNMVYGRTPF 45
>29590
          Length = 320

 Score = 45.1 bits (105), Expect(2) = 2e-09,   Method: Composition-based stats.
 Identities = 17/39 (43%), Positives = 25/39 (64%)
 Frame = +3

Query: 175 GTPGYLSPEVLRKDPYGKPVDLWACGVILYILLVGYPPF 213
           GTP Y++PEVL  +P     D+W+ GV+ Y++L    PF
Sbjct: 60  GTPDYVAPEVLDYEPLSIQTDMWSLGVLSYVMLTACSPF 176

 Score = 35.0 bits (79), Expect(2) = 2e-09,   Method: Composition-based stats.
 Identities = 15/46 (32%), Positives = 24/46 (52%)
 Frame = +2

Query: 216 EDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPSKRIT 261
           ++Q   +  I     DFP   +  ++P AKD I K+L  +P  R+T
Sbjct: 182 DNQQETFCNISQVKLDFPDDLFSHISPHAKDFIKKLLVKDPRHRMT 319
>19094
          Length = 898

 Score = 50.1 bits (118), Expect(2) = 5e-09,   Method: Compositional matrix adjust.
 Identities = 27/93 (29%), Positives = 50/93 (53%)
 Frame = +1

Query: 109 EADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQ 168
           E + +  +   L+ + + H    +HRD+K  N+LL ++      KLADFG+A ++     
Sbjct: 55  EREIATILYYTLKGL*YLHSRRKIHRDIKAGNILLNNE---GHAKLADFGVAGQLTDTMA 225

Query: 169 AWFGFAGTPGYLSPEVLRKDPYGKPVDLWACGV 201
                 GTP +++PEV+++  Y    D+W+ G+
Sbjct: 226 KRNTVIGTPYWMAPEVIQEIGYDCVADIWSLGI 324

 Score = 28.5 bits (62), Expect(2) = 5e-09,   Method: Compositional matrix adjust.
 Identities = 21/66 (31%), Positives = 29/66 (43%), Gaps = 3/66 (4%)
 Frame = +3

Query: 209 GYPPFWDEDQHRLYQQIKAGAYDFPSPEW---DTVTPEAKDLINKMLTINPSKRITAAEA 265
           G PP+ D    R    I       P P +   D  + E  D ++K L  NP  R TA + 
Sbjct: 345 GKPPYGDIHPMRAIFMIPTK----PPPSFRQPDKWSTEFIDFVSKCLVKNPENRATAVDL 512

Query: 266 LKHPWI 271
           L+H +I
Sbjct: 513 LQHDFI 530
>01756
          Length = 1858

 Score = 58.2 bits (139), Expect = 7e-09,   Method: Compositional matrix adjust.
 Identities = 56/214 (26%), Positives = 95/214 (44%), Gaps = 22/214 (10%)
 Frame = -3

Query: 12   EYQLFEELGKGAFSVV--RRCVKVLAGQEYAAKIINTKKLSARDHQK-----LEREARIC 64
            +Y+   ++G+G F  V   RC K         +++  KK+   + ++       RE +I 
Sbjct: 1739 KYEKLAKIGQGTFGEVFKARCKKT-------KQVVAMKKVLMDNEKEGFPITALREIKIL 1581

Query: 65   RLLKHPNIVRLHDSISEEG--------HHYLIFDLV---TGGELFEDIVAREYYSEADAS 113
            +LL H N+V L +  S +           YL+F+       G L    V    ++  +  
Sbjct: 1580 QLLNHENVVDLIEICSTKATSANRYKSMFYLVFEFCEHDLAGLLSNMSVV---FNLPEIK 1410

Query: 114  HCIQQILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGL--AIEVEGEQ-QAW 170
              ++Q++  + + H+  ++HRD+K  N+L+    K   +KLADFGL  A  V   Q   +
Sbjct: 1409 EVMKQLMNGLYYIHRNKILHRDMKAANILIT---KQGVLKLADFGLARAFSVNLRQPNRY 1239

Query: 171  FGFAGTPGYLSPEVLRKD-PYGKPVDLWACGVIL 203
                 T  Y  PE+L  D  Y   +D W  G I+
Sbjct: 1238 TNRVVTLWYRPPELLLGDRNYSTAIDQWGAGCIM 1137
>04591
          Length = 1117

 Score = 58.2 bits (139), Expect = 8e-09,   Method: Compositional matrix adjust.
 Identities = 48/157 (30%), Positives = 79/157 (50%), Gaps = 12/157 (7%)
 Frame = -2

Query: 59   REARICRLLKHPNIVRLHDSI-SEEGHH-------YLIF---DLVTGGELFEDIVAREYY 107
            RE +I + L+H N+V+L +   ++ G +       YLIF   D    G L  ++  R  +
Sbjct: 1074 REIKILQQLEHENVVQLQEICHTQAGPYNRYKSTFYLIFEYCDYDLAG-LLNNL--RVKF 904

Query: 108  SEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQ 167
            S AD  + + Q+L  + + H   ++HRD+K  N+LL    +   +KLADFGL+     + 
Sbjct: 903  SLADKKNLMSQLLNGLFYIHTKQILHRDIKAANILLT---RDGVLKLADFGLS-RPWVKS 736

Query: 168  QAWFGFAGTPGYLSPEVLRKD-PYGKPVDLWACGVIL 203
            +       T  Y  PE+L  +  YG  +D+W  G I+
Sbjct: 735  KRLTNRVVTLWYRPPELLLGEREYGPEIDMWGVGCIM 625
>27546
          Length = 426

 Score = 56.2 bits (134), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 38/103 (36%), Positives = 53/103 (51%), Gaps = 1/103 (0%)
 Frame = -1

Query: 59  REARICRLLKHPNIVRLHDSISEEGHHYLIF-DLVTGGELFEDIVAREYYSEADASHCIQ 117
           RE  I   L HPNI+++H SI + G    IF      G++   I       EA       
Sbjct: 333 RELEILTRLDHPNIIQIH-SILQRGPKIFIFMRYAEKGDMLSHIKKTGPIDEAQTKVWFF 157

Query: 118 QILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLA 160
           Q+ +A+ + H   + HRDLK EN+LL+ +L    VK+ADFG A
Sbjct: 156 QMAKALQYLHSHDIAHRDLKCENILLSKRLN---VKIADFGFA 37
>18663
          Length = 600

 Score = 55.5 bits (132), Expect = 5e-08,   Method: Compositional matrix adjust.
 Identities = 34/97 (35%), Positives = 51/97 (52%), Gaps = 9/97 (9%)
 Frame = +2

Query: 173 FAGTPGYLSPEVLRKDPYGKPVDLWACGVILYILLVGYPPF------WDEDQHR---LYQ 223
           F GTP Y++PE+LR + YG  VD WA GV+LY +L G  PF       + DQ+    L+Q
Sbjct: 8   FCGTPNYIAPEILRGEDYGFSVDWWALGVLLYEMLAGRSPFDIAGASENPDQNTEDYLFQ 187

Query: 224 QIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPSKRI 260
            I       P     +++ +A  ++   L  NP+ R+
Sbjct: 188 VILEKTIRIPR----SLSVKAASVLKGFLNKNPADRL 286
>11185
          Length = 473

 Score = 55.5 bits (132), Expect = 5e-08,   Method: Compositional matrix adjust.
 Identities = 45/167 (26%), Positives = 75/167 (44%), Gaps = 23/167 (13%)
 Frame = +1

Query: 125 HCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGE--QQAWFGFA-------- 174
           + H +G++  DL+P  +LL +      +K ADFGL+ +VEGE  ++ +F FA        
Sbjct: 46  YIHSLGILFHDLRPSKVLLDTS---GVLKFADFGLS-KVEGENLEELFFKFAEAGDQWNI 213

Query: 175 -------------GTPGYLSPEVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRL 221
                        G+P Y++PEV +        DLWA G + Y +  G          RL
Sbjct: 214 QSAEEMMKQVPTSGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFSG---------SRL 366

Query: 222 YQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPSKRITAAEALKH 268
             +        PSPE+        +L+  +L  + ++R++ A  +KH
Sbjct: 367 SAK--------PSPEF-------LNLLESLLQKDSTRRLSWASLVKH 462
>20655
          Length = 1181

 Score = 55.1 bits (131), Expect = 7e-08,   Method: Compositional matrix adjust.
 Identities = 21/57 (36%), Positives = 35/57 (61%)
 Frame = +2

Query: 221 LYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPSKRITAAEALKHPWISHRSTV 277
           + ++I+ G Y+FP PEW  V+ +AKDLI  ML  +P KR+   + +   W++  + V
Sbjct: 2   MKKRIRNGQYEFPKPEWSRVSQDAKDLIRGMLCTDPDKRLNIKQVMASKWVADNTMV 172
>04138
          Length = 800

 Score = 54.7 bits (130), Expect = 8e-08,   Method: Compositional matrix adjust.
 Identities = 55/182 (30%), Positives = 77/182 (42%), Gaps = 34/182 (18%)
 Frame = +1

Query: 121 EAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGL--AIEVEGEQ-QAWFGFAGTP 177
           E + + H+  ++HRD+K  N+L+    K   +KLADFGL  A  V   Q   +     T 
Sbjct: 46  ERLYYIHRNKILHRDMKAANILIT---KQGVLKLADFGLARAFSVNLRQPNRYTNRVVTL 216

Query: 178 GYLSPEVLRKD-PYGKPVDLWACGVI---------------------LYILLVG--YPPF 213
            Y  PE+L  D  Y   +D W  G I                     L   L G   P  
Sbjct: 217 WYRPPELLLGDRNYSTAIDQWGAGCIMAEMWTRNPIMQGTTEQNQLTLITQLCGSITPEV 396

Query: 214 W-DEDQHRLYQQIK----AGAYDFPSPEWDTVT--PEAKDLINKMLTINPSKRITAAEAL 266
           W    Q  +Y QIK    AG  +     +  +   P   DL  ++L ++PS+RI+A EAL
Sbjct: 397 WPGVTQLSMYHQIKGALAAGRKNIIRDRFARILKDPYGLDLFERLLKMDPSQRISADEAL 576

Query: 267 KH 268
            H
Sbjct: 577 NH 582
>27274
          Length = 396

 Score = 53.1 bits (126), Expect = 2e-07,   Method: Composition-based stats.
 Identities = 29/98 (29%), Positives = 52/98 (53%), Gaps = 8/98 (8%)
 Frame = -1

Query: 183 EVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHR--------LYQQIKAGAYDFPS 234
           E+LR   +G  VD+W+ G++L+ LL G+ PF  E   R        +Y QI  G+     
Sbjct: 375 ELLRGQQHGPTVDMWSLGILLHELLSGHVPFEPERGSRQMARNMMAVYAQIIRGS-SRDV 199

Query: 235 PEWDTVTPEAKDLINKMLTINPSKRITAAEALKHPWIS 272
            +   ++    D + +++ +  +KR+T+ +A  HPWI+
Sbjct: 198 CDGLALSTHGADFLRRLVQLEDTKRLTSQQAFSHPWIA 85
>31120
          Length = 439

 Score = 52.8 bits (125), Expect = 3e-07,   Method: Composition-based stats.
 Identities = 30/90 (33%), Positives = 47/90 (52%), Gaps = 1/90 (1%)
 Frame = +1

Query: 183 EVLRKDPYG-KPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVT 241
           EV+   PY  K  D W+ GVIL+I+L G  PF D + ++L +  ++  Y F     D V+
Sbjct: 1   EVVCGVPYDPKMADAWSLGVILFIMLNGKMPFDDSNLNKLLEDQRSKKYSFRRKLQDLVS 180

Query: 242 PEAKDLINKMLTINPSKRITAAEALKHPWI 271
           P A+  ++ +L  N + R    E L   W+
Sbjct: 181 PNARSTVSVLLEPNSAMRWDLNEVLNCQWL 270
>02638
          Length = 1490

 Score = 52.0 bits (123), Expect = 6e-07,   Method: Compositional matrix adjust.
 Identities = 29/102 (28%), Positives = 52/102 (50%), Gaps = 1/102 (0%)
 Frame = +1

Query: 175 GTPGYLSPEVLRKDPYGKPVDLWACGVILYILLVGYPPFWDED-QHRLYQQIKAGAYDFP 233
           GT  +++PEVLR + YG+  D+W+ G ++  +    PP+   D  + L    K  +   P
Sbjct: 22  GTIAFMAPEVLRGESYGRACDVWSVGCVMIEMCTCRPPWNSHDISNHLALIFKIASSVDP 201

Query: 234 SPEWDTVTPEAKDLINKMLTINPSKRITAAEALKHPWISHRS 275
            P  + ++P  +DL+ + L  +   R +A + L HP  +  S
Sbjct: 202 PPIPENMSPPVRDLMLRCLEQDSDFRPSAKDLLMHPLFTKYS 327
>32000
          Length = 644

 Score = 51.2 bits (121), Expect = 9e-07,   Method: Compositional matrix adjust.
 Identities = 44/148 (29%), Positives = 74/148 (50%), Gaps = 25/148 (16%)
 Frame = -1

Query: 150 AAVKLADFGLAIEVEGEQQAWFGFAGTPGYLSPEVLRK-DPYGKPVDLWACGVILYILLV 208
           A +K+ADFGLA       + +     T  Y +PE+L     Y  PVD+W+ G I   ++ 
Sbjct: 578 AKMKIADFGLARVFGLPVRTYTHEVITLWYRAPEILLGCRFYSVPVDIWSLGCIFVEMMT 399

Query: 209 G---YPPFWDEDQ-HRLY-------QQIKAGAYDFPS-----PEW-----DTVTPEAK-- 245
               +P   + DQ +R++       +++  G    P      P+W     +TV   +K  
Sbjct: 398 RRALFPGDSEIDQLYRIFRTLGTPDEKVWPGVSKLPDYKPTFPKWPLKNLETVVSLSKVG 219

Query: 246 -DLINKMLTINPSKRITAAEALKHPWIS 272
            DL+ +MLT NP++RI+A  A++HP+ +
Sbjct: 218 LDLLKRMLTYNPNRRISARSAMRHPYFN 135
>17300
          Length = 480

 Score = 51.2 bits (121), Expect = 9e-07,   Method: Compositional matrix adjust.
 Identities = 33/112 (29%), Positives = 56/112 (50%), Gaps = 7/112 (6%)
 Frame = +1

Query: 129 MGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPG------YLSP 182
           MG VHRDL   N+L+   L     K+ADFGL+ E+E +     G   T G      + +P
Sbjct: 31  MGYVHRDLAARNILVNEIL---VCKVADFGLSREIESDTTE--GAYTTKGGKIPVRWTAP 195

Query: 183 EVLRKDPYGKPVDLWACGVILY-ILLVGYPPFWDEDQHRLYQQIKAGAYDFP 233
           E +    +    D+W+ GV+++ ++  G  P+W+     + + ++ G Y  P
Sbjct: 196 EAIAYRKFTSASDVWSFGVVMWEVMSYGERPYWNWSNQDVIKAVEKG-YRLP 348
>19301
          Length = 712

 Score = 51.2 bits (121), Expect = 9e-07,   Method: Compositional matrix adjust.
 Identities = 41/145 (28%), Positives = 65/145 (44%)
 Frame = +2

Query: 16  FEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRL 75
            E LG GA   V   +  L  +E A K +   K         E + R  R L HPNI+  
Sbjct: 320 LEWLGSGAQGAV--FLGKLCAEEVAVKKVRDIK---------ETDIRNLRKLNHPNIISF 466

Query: 76  HDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRD 135
               ++   + +I +    G+L+E +   +    A      +QI   + + H   ++HRD
Sbjct: 467 KGVCTQAPCYCIIMEYCPYGQLYEVLRDGKEIPPALVLDWSKQIASGMNYLHSHKIIHRD 646

Query: 136 LKPENLLLASKLKGAAVKLADFGLA 160
           LK  N+L+A   K   VK++DFG +
Sbjct: 647 LKSPNVLVA---KNDVVKISDFGTS 712
>04852
          Length = 1462

 Score = 51.2 bits (121), Expect = 9e-07,   Method: Compositional matrix adjust.
 Identities = 50/218 (22%), Positives = 92/218 (42%), Gaps = 30/218 (13%)
 Frame = +1

Query: 49  LSARDHQKLEREARICRLLK----HPNIVRLHDSISEEGHHYLIFDLVTGGEL------- 97
           ++A + Q   +E ++ + +K    H NIV      ++ G  ++I +    G L       
Sbjct: 55  VTAVEEQDFVQELQVMKAVKKMGSHINIVNFLGCCTQGGPLWVIVEFAKNGNLRDFLESC 234

Query: 98  ------FEDIVARE---YYSEADASHCIQ---------QILEAVLHCHQMGVVHRDLKPE 139
                 +   V+ +   +Y++    H I+         QI   +        +HRDL   
Sbjct: 235 RDGINGYGKFVSPQDPGWYTKTPGGHVIRRKNLLSYAFQIARGMEFLASRKCIHRDLAAR 414

Query: 140 NLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDLWAC 199
           N+L+  +     +K+ADFGL+   +  ++   G      +++PE L    Y    D+W+ 
Sbjct: 415 NVLVTEE---HVLKIADFGLSRTGDYYKKRSGGRLPVK-WMAPEALFDMRYTTKSDVWSF 582

Query: 200 GVILY-ILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPE 236
           GV+L+ I  +G  P+       LY ++   AY  P PE
Sbjct: 583 GVVLWEIFSLGGMPYASIPNEELYSKLLDDAYRMPRPE 696
>03508
          Length = 1463

 Score = 50.4 bits (119), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 44/198 (22%), Positives = 90/198 (45%), Gaps = 5/198 (2%)
 Frame = +1

Query: 11  EEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREARICRLLKHP 70
           ++YQ+  +LG+G +S V   + V   +    K +       +  +       +  L    
Sbjct: 589 DDYQIVRKLGRGKYSEVFEAINVTNNE----KCVIKILKPVKKKKIKREIKILENLRGGT 756

Query: 71  NIVRL----HDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHC 126
           N++ L     D +S      LIF+ V   +  +     + +++ D    + ++++A+  C
Sbjct: 757 NVITLLAIVKDPVSRTPA--LIFEHVNNTDFKQ---LYQTFTDYDIRFYLYELMKALDFC 921

Query: 127 HQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLSPEVLR 186
           H MG++HRD+KP N+++  + K   ++L D+GLA E       +     +  +  PE+L 
Sbjct: 922 HSMGIMHRDVKPHNVMIDHENK--KLRLIDWGLA-EFYHPGMEYNVRVASRYFKGPELLL 1092

Query: 187 K-DPYGKPVDLWACGVIL 203
               Y   +D+W+ G + 
Sbjct: 1093DYQMYDYSLDMWSLGCMF 1146

 Score = 36.6 bits (83), Expect = 0.022,   Method: Compositional matrix adjust.
 Identities = 13/32 (40%), Positives = 24/32 (75%)
 Frame = +2

Query: 240  VTPEAKDLINKMLTINPSKRITAAEALKHPWI 271
            ++PEA D ++K+L  + ++R+TA EA+ HP+ 
Sbjct: 1358 ISPEALDFLDKLLRYDHNERLTAREAMDHPYF 1453
>28157
          Length = 400

 Score = 49.7 bits (117), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 38/133 (28%), Positives = 67/133 (50%), Gaps = 6/133 (4%)
 Frame = +3

Query: 37  QEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGGE 96
           ++ A K I +++      Q+L++ +R+     HPNIV L+ +  +     L+ +   GG 
Sbjct: 3   KDVAVKRIESEQEKKSFMQELKQLSRV----SHPNIVCLYGACRDHPV-CLVMEYAEGGS 167

Query: 97  LFEDIVAREYYSEADASHCIQQILEAVL---HCHQM---GVVHRDLKPENLLLASKLKGA 150
           L+  +       +  A+H +  +L+  L   + H M    ++HRDLKP NLLL     G 
Sbjct: 168 LYNVLHGSGPQPQYTAAHAMNWLLQCALGVEYLHGMKPKALIHRDLKPPNLLLIQ--CGT 341

Query: 151 AVKLADFGLAIEV 163
            +K+ DFG A ++
Sbjct: 342 KLKICDFGTACDI 380
>17722
          Length = 680

 Score = 48.9 bits (115), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 24/72 (33%), Positives = 40/72 (55%)
 Frame = -3

Query: 194 VDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLT 253
           VD W  GV++Y ++ G  PF++ D   L++ I      FP      ++ EAK L++ +L 
Sbjct: 678 VDWWGTGVVMYEMMCGRLPFYNRDHDVLFELILLQNVKFPR----NLSEEAKTLLSGLLA 511

Query: 254 INPSKRITAAEA 265
            NP +R+  +EA
Sbjct: 510 KNPKRRLGGSEA 475
>14116
          Length = 1017

 Score = 48.5 bits (114), Expect = 7e-06,   Method: Compositional matrix adjust.
 Identities = 51/204 (25%), Positives = 88/204 (43%), Gaps = 13/204 (6%)
 Frame = -1

Query: 17  EELGKGAFSVVRRCVKVLAGQE----YAAKIINTKKLSARDHQKLEREARICRLLKHPNI 72
           EE+GKG F  V+R    L  Q+     A K ++       + Q   +EA I +   H N+
Sbjct: 618 EEIGKGNFGCVKRGFLTLPEQKGDILVAVKTLHNNNPREIELQSFLQEALIMKDFHHSNV 439

Query: 73  VRLHD-SISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQ---QILEAVLHCHQ 128
           + L    ++ +    ++   +  G+L   I  R+   +      I     I   + +   
Sbjct: 438 LTLIGICLNLDDMPLVVLPFMKHGDLLTYI--RDDQHQPTIKDLIMYGVDIARGMDYLAG 265

Query: 129 MGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPG-----YLSPE 183
           +  VHRDL   N +L        VK+ADFGLA ++   ++ ++            +++ E
Sbjct: 264 LKFVHRDLAARNCMLDEDFH---VKVADFGLARDIY--EKEYYSSENKKAKLPVKWMALE 100

Query: 184 VLRKDPYGKPVDLWACGVILYILL 207
            L K  Y    D+W+ GV+L+ LL
Sbjct: 99  SLEKGNYDSKTDVWSYGVVLWELL 28
>00715
          Length = 1788

 Score = 48.1 bits (113), Expect = 8e-06,   Method: Compositional matrix adjust.
 Identities = 50/200 (25%), Positives = 85/200 (42%), Gaps = 30/200 (15%)
 Frame = +1

Query: 67  LKHPNIVRLHDSIS----EEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQ---QI 119
           L+H N+V +  + S    E+G  +L  + V  G L    +  ++  + D+S  +    Q+
Sbjct: 97  LRHVNVVSILGATSLHRFEDGA-WLAMEYV--GPLNLQTILNDHQQDIDSSMRLSLALQM 267

Query: 120 LEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLA------------------- 160
              + + H + +VH DLKP N LL   LK   +++ADFG                     
Sbjct: 268 ARGLHYLHSINIVHLDLKPANCLLTRDLK---LRIADFGCCHQLTPTGLDMGEREGGMAG 438

Query: 161 --IEVEGEQQAWFG-FAGTPGYLSPEVLRKDPYGKPVDLWACGVILYILLVGYPPFWDED 217
             +E+   Q AW    AGT  Y +PE+L+        D+++ G+ L+ +     P+    
Sbjct: 439 NELELTPVQGAWKNELAGTLAYRAPELLKGLQPSVRSDVYSLGITLWQMCTRQGPYEGVP 618

Query: 218 QHR-LYQQIKAGAYDFPSPE 236
            H  +YQ +       P P 
Sbjct: 619 AHAVVYQVVSKDLRPCPPPS 678
>11780
          Length = 1713

 Score = 47.0 bits (110), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 43/152 (28%), Positives = 72/152 (47%), Gaps = 2/152 (1%)
 Frame = +3

Query: 11  EEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREARICRLLKHP 70
           ++ ++ E +GKG F  V +   +  GQ  A K +  K    R  Q   +EA +   L+H 
Sbjct: 597 QDLEIGEAIGKGDFGDVYK--GMYRGQPVAIKQLKDKD---RGEQSFLQEASVMTSLRHD 761

Query: 71  NIVRLHDSISEEGHHYLIFDLVTGGELFEDIVA--REYYSEADASHCIQQILEAVLHCHQ 128
           N+VRL   +  E   +L+ + +  G L E + +  R   ++ D  +       A+ +   
Sbjct: 762 NLVRLIGVVLGE-TIFLVTEFMGKGNLVEYLRSRGRSVITKKDQINFATDTCAAMEYLES 938

Query: 129 MGVVHRDLKPENLLLASKLKGAAVKLADFGLA 160
             +VHRDL   N+L+    K    K++DFGLA
Sbjct: 939 KRLVHRDLAARNVLVHDDGK---AKVSDFGLA 1025
>36481
          Length = 806

 Score = 46.6 bits (109), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 45/150 (30%), Positives = 66/150 (44%), Gaps = 7/150 (4%)
 Frame = +2

Query: 2   ATITCTRFTEEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKII-NTKKLSARDHQKLERE 60
            T+  T  T + +L    G+G F  V +C  +L G + A KII N  K   R+  KLE  
Sbjct: 335 CTMRGTSSTNDMKLCPHWGEGTFGKVVQCKDLLKGDDIALKIIKNVDKY--REAAKLEIN 508

Query: 61  ARICRLLKHPN----IVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREY--YSEADASH 114
                  K P+     V++ D     GH  + F ++ G  +F+ +    Y  Y      H
Sbjct: 509 VLEKLREKDPHAKHMCVQMLDWFDYHGHVCISFHML-GLSVFDFLKDNSYGAYPIEQVRH 685

Query: 115 CIQQILEAVLHCHQMGVVHRDLKPENLLLA 144
              Q+  AV   H+  + H DLKPEN+L  
Sbjct: 686 ISYQLCYAVNFLHENQLTHTDLKPENILFV 775
>00394
          Length = 548

 Score = 46.2 bits (108), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 27/86 (31%), Positives = 44/86 (51%), Gaps = 5/86 (5%)
 Frame = -2

Query: 17  EELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLH 76
           +E+G+G+F  V + +    G   A   +  KK +  + Q+ + EA + + L+HPNIVR  
Sbjct: 280 KEIGRGSFKTVYKGLDTELGVAVAWCELQDKKWNKAERQRFKEEAEMLKELQHPNIVRFF 101

Query: 77  DSISEEGHH-----YLIFDLVTGGEL 97
           D   E  H       L+ +L+T G L
Sbjct: 100 DYWEEHNHRNRKVIILVTELMTSGTL 23
>31789
          Length = 676

 Score = 45.4 bits (106), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 27/85 (31%), Positives = 43/85 (50%), Gaps = 5/85 (5%)
 Frame = +2

Query: 18  ELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHD 77
           E+G+G+F  V + +    G   A   +  KK +  + Q+ + EA + + L+HPNIVR  D
Sbjct: 341 EIGRGSFKTVYKGLDTELGVAVAWCELQDKKWNKTERQRFKEEAEMLKELQHPNIVRFFD 520

Query: 78  SISEEGHH-----YLIFDLVTGGEL 97
              E  H       L+ +L+T G L
Sbjct: 521 YWEEHNHRNRKVIILVTELMTSGTL 595
>31489
          Length = 329

 Score = 43.9 bits (102), Expect = 1e-04,   Method: Composition-based stats.
 Identities = 27/87 (31%), Positives = 48/87 (55%), Gaps = 6/87 (6%)
 Frame = +3

Query: 62  RICRLLKHPNIVRLHDSIS-EEGHH-----YLIFDLVTGGELFEDIVAREYYSEADASHC 115
           +I +  KH NI+ + + +  ++ +H     +++FDL+   +L   I + +  +E    + 
Sbjct: 6   KILKHFKHDNIISIREILKPKDSYHDFKDIHVVFDLMES-DLHRIIYSDQPLTEEHIRYF 182

Query: 116 IQQILEAVLHCHQMGVVHRDLKPENLL 142
           + QIL  + + H   VVHRDLKP NLL
Sbjct: 183 LYQILRGLKYIHSANVVHRDLKPSNLL 263
>07291
          Length = 833

 Score = 43.9 bits (102), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 29/118 (24%), Positives = 60/118 (50%), Gaps = 6/118 (5%)
 Frame = +1

Query: 117 QQILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGT 176
           +QI + + +  ++ VVHR+L   N ++    +   ++L+D+G+   +    Q+++    +
Sbjct: 70  RQIADGMAYLQEVKVVHRNLAARNCIVT---EDGRLQLSDYGVTGSLF--PQSYYTADDS 234

Query: 177 PG-----YLSPEVLRKDPYGKPVDLWACGVILYILLV-GYPPFWDEDQHRLYQQIKAG 228
           P      +++PE +    +    D+WA GV+L+ LL  G  P+ D +   L   +K G
Sbjct: 235 PARDLVKWMAPETIDNFHFSSKSDVWAFGVVLWELLTRGITPYPDVENSSLLPYLKEG 408
>25019
          Length = 730

 Score = 43.9 bits (102), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 26/62 (41%), Positives = 34/62 (54%)
 Frame = +3

Query: 139 ENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDLWA 198
           EN+LL    K   VKL DFGL  E     +    F GT  Y++PE+L +  +GK VD W+
Sbjct: 261 ENVLLD---KDGHVKLTDFGLCKEAITGTRVTHTFCGTIEYMAPEILTRTGHGKAVDWWS 431

Query: 199 CG 200
            G
Sbjct: 432 LG 437
>18481
          Length = 437

 Score = 42.0 bits (97), Expect = 6e-04,   Method: Compositional matrix adjust.
 Identities = 35/130 (26%), Positives = 65/130 (50%), Gaps = 5/130 (3%)
 Frame = -1

Query: 36  GQEYAAKI--INTKKLSARDHQKLEREARIC-RLLKHPNIVRLHDSISEEGHHYLIFDLV 92
           G++ A KI  I+ K      HQ L  EA++  ++ +HP +  ++   +E+  + L+ +L+
Sbjct: 410 GKDIAVKIEAIDVK------HQLLHYEAKVYEQIGRHPGLPTMYHYGTEKHFNALVMELL 249

Query: 93  TGG--ELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKLKGA 150
                ELF  ++ +  ++         Q+L  +   HQ   +HRDLKP+N L+       
Sbjct: 248 GPSLEELF--VICKRRFTLKTILMVSDQLLSRLEFIHQKCFIHRDLKPDNFLMGLGRHCH 75

Query: 151 AVKLADFGLA 160
            + + DFGL+
Sbjct: 74  RLYIIDFGLS 45
>32957
          Length = 645

 Score = 40.8 bits (94), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 21/51 (41%), Positives = 29/51 (56%)
 Frame = +3

Query: 157 FGLAIEVEGEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDLWACGVILYILL 207
           F L +E  G +     F GT  Y++PEV  +  YGK VD W  G++L+ LL
Sbjct: 3   FALCVEKSGGRTR--TFCGTREYMAPEVHERKEYGKEVDWWGLGILLHELL 149
>07940
          Length = 1336

 Score = 40.4 bits (93), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 30/102 (29%), Positives = 50/102 (49%), Gaps = 6/102 (5%)
 Frame = -3

Query: 118 QILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTP 177
           Q+   + +      +HRDL   N+L+A +     +K+ADFGL   +   QQ  +    T 
Sbjct: 323 QVARGMEYLASKQCIHRDLAARNVLVAEEY---VLKIADFGLTRNL---QQFDYYRKTTD 162

Query: 178 G-----YLSPEVLRKDPYGKPVDLWACGVILY-ILLVGYPPF 213
           G     +++PE L    Y    D+W+ GV+L+ I  +G  P+
Sbjct: 161 GRLPVKWMAPEALFDRKYTSKSDVWSYGVLLWEIFTLGGNPY 36
>12672
          Length = 773

 Score = 40.4 bits (93), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 29/98 (29%), Positives = 48/98 (48%), Gaps = 4/98 (4%)
 Frame = +3

Query: 116 IQQILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEV---EGEQ-QAWF 171
           ++     + + +  G VHRD+K  N+LL S+      K+ DF   +     EG+  Q   
Sbjct: 9   VKGTASGIQYLNDNGHVHRDIKTANILLDSEYTA---KVGDFATVVSAPSGEGKTVQNAS 179

Query: 172 GFAGTPGYLSPEVLRKDPYGKPVDLWACGVILYILLVG 209
              GT  YL+PE +  D   K +D ++ GV+L  ++ G
Sbjct: 180 VVIGTAAYLAPEAIHFDVSTK-LDSYSFGVVLLEVITG 290
>01106
          Length = 878

 Score = 40.4 bits (93), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 39/148 (26%), Positives = 67/148 (45%), Gaps = 12/148 (8%)
 Frame = +3

Query: 9   FTEEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKL---SARDHQKLEREARICR 65
           F   Y +  +LG G FS V  C  +   +  A K++ + +    +A D  KL +  R   
Sbjct: 312 FNGRYHVIRKLGWGHFSTVWLCWDLTCKRFVALKVVKSAQHYTETALDEVKLLKCVRESD 491

Query: 66  LLK--HPNIVRLHDSISEEG----HHYLIFDLVTGGELFEDIVAREYYSEA--DASHCIQ 117
           +        V+L D     G    H  ++F+ V G  L + I+   Y      +    I+
Sbjct: 492 VADPARAKCVQLLDDFKISGVNGTHVAMVFE-VLGYNLLKLIIRSNYQGIPIHNVKLIIR 668

Query: 118 QILEAVLHCH-QMGVVHRDLKPENLLLA 144
           Q+LE + + H +  ++H D+KPEN+L+ 
Sbjct: 669 QVLEGLSYMHAKCRIIHTDIKPENILIC 752
>08294
          Length = 1849

 Score = 39.7 bits (91), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 54/212 (25%), Positives = 86/212 (40%), Gaps = 17/212 (8%)
 Frame = +2

Query: 70   PNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVA-REYYSEADASHCI-----------Q 117
            PNIV       E   H+LI +    G+L + ++A R        +              Q
Sbjct: 887  PNIVHFMGVCREAEPHFLITEYCDWGDLKQFLLATRNDNGRGRGTRVPALALSQKLGMGQ 1066

Query: 118  QILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTP 177
            Q+   +      G+VH DL   N+LL S+++   +K+A   L+ +V   +         P
Sbjct: 1067 QVAAGMEALSNQGLVHGDLAARNVLLTSRMQ---LKVARPALSGDVYASEYYPLHQRLVP 1237

Query: 178  -GYLSPEVLRKDPYGKPVDLWACGVILYILL----VGYPPFWDEDQHRLYQQIKAGAYDF 232
              +L PE + +D      D+WA GV L+ +L    + Y    DE+  R  Q  +A A D 
Sbjct: 1238 LRWLPPEGVLEDSATTCGDVWAFGVFLWEVLQLADLPYRLMSDEEVLRSLQHSQA-ALDS 1414

Query: 233  PSPEWDTVTPEAKDLINKMLTINPSKRITAAE 264
            P        P    L+ +     PS+R   +E
Sbjct: 1415 PD-----APPALLSLLQRCTAQQPSQRPPFSE 1495
>18287
          Length = 678

 Score = 39.7 bits (91), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 20/42 (47%), Positives = 26/42 (61%), Gaps = 1/42 (2%)
 Frame = -3

Query: 241 TPEAKDLINKMLTINPSKRITAAEALKHPWISH-RSTVASCM 281
           T EA  L+ +ML +NP  RI+A EAL HP++   R    SCM
Sbjct: 436 THEAVRLLTRMLILNPKNRISAEEALSHPYLDEGRVRFHSCM 311
>29360
          Length = 363

 Score = 39.7 bits (91), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 21/77 (27%), Positives = 38/77 (49%), Gaps = 3/77 (3%)
 Frame = +3

Query: 71  NIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHC---IQQILEAVLHCH 127
           N VR  +    + H  L+F+++       D + +  +      +     QQ+L A+    
Sbjct: 138 NFVRAFECFQHKNHTCLVFEMLEQN--LYDFLKQNKFQPLPLKYIRPITQQVLTALRKLK 311

Query: 128 QMGVVHRDLKPENLLLA 144
           Q+G++H DLKPEN++L 
Sbjct: 312 QLGLIHADLKPENIMLV 362
>11404
          Length = 563

 Score = 38.9 bits (89), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 37/149 (24%), Positives = 67/149 (44%), Gaps = 11/149 (7%)
 Frame = +1

Query: 8   RFTEEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREARICRLL 67
           ++ + Y++   +GKG+F  V +       ++ A KII  KK      Q    E ++  ++
Sbjct: 130 KWADRYEIDSLIGKGSFGQVVKAYDHTDNEQVAIKIIKNKKPFLNQAQI---EVKLLEMM 300

Query: 68  KHPN------IVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADAS---HCIQQ 118
              +      IVRL        H  L+F+L++      D++    +     +      QQ
Sbjct: 301 NRHDTDNKYYIVRLKRHFMFRSHLCLVFELLSYN--LYDLLRNTNFRGVSLNLTRKFAQQ 474

Query: 119 ILEAVLHCH--QMGVVHRDLKPENLLLAS 145
           +  A+L     +M ++H DLKPEN+LL +
Sbjct: 475 LCTALLFLATPEMSIIHCDLKPENILLCN 561
>23319
          Length = 2235

 Score = 38.5 bits (88), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 31/117 (26%), Positives = 51/117 (43%), Gaps = 26/117 (22%)
 Frame = +3

Query: 182 PEVLRKDPYGKPVDLWACGVILYILLVGYPPFW----DEDQ-HRLYQQIKAGAYD----- 231
           P+V     Y   +D+W+ G I   L     P +    D+DQ  R+++ +     D     
Sbjct: 3   PDVYXAKMYSTSIDMWSAGCIFAELANAGRPLFPGNDDDDQLKRIFKLLGTPTEDQWPGM 182

Query: 232 --------FP----SPEWDTVTPE----AKDLINKMLTINPSKRITAAEALKHPWIS 272
                   FP    +  W  V P+     +DL+  +L   PS R++A EAL+HP+ +
Sbjct: 183 TQLPNYRMFPMYHVTTTWQQVVPKLNSKGRDLLQCLLVCCPSDRMSADEALQHPYFA 353
>18401
          Length = 463

 Score = 37.7 bits (86), Expect = 0.009,   Method: Compositional matrix adjust.
 Identities = 31/140 (22%), Positives = 52/140 (37%), Gaps = 41/140 (29%)
 Frame = -3

Query: 174 AGTPGYLSPEVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQ--------------- 218
             T  Y +PEV+ +  +  P D+W+ G I++ L  GY  F   D                
Sbjct: 449 VSTRHYRAPEVILELGWSHPCDVWSVGCIMFELYTGYTLFQTHDNKEHLAMMERILGSLP 270

Query: 219 HRLYQQIKAGAY----DFPSPEWDTVTPEAK----------------------DLINKML 252
           +R+ ++ K   Y        PE  ++    +                      DL+ K+L
Sbjct: 269 YRMAKKTKKQKYFHHGRLDVPERSSMARYVRENTKPLLRYVKDRENKDHQQLFDLMKKLL 90

Query: 253 TINPSKRITAAEALKHPWIS 272
               S R +  +AL+HP+ S
Sbjct: 89  AYEASSRYSLLQALQHPFFS 30
>20513
          Length = 405

 Score = 37.4 bits (85), Expect = 0.015,   Method: Compositional matrix adjust.
 Identities = 16/37 (43%), Positives = 24/37 (64%), Gaps = 1/37 (2%)
 Frame = -1

Query: 236 EWDTVTPEA-KDLINKMLTINPSKRITAAEALKHPWI 271
           EWD    +A  D +  ML  +P +R TAA++L+HPW+
Sbjct: 315 EWDPKDAKAFADFLAPMLEFDPEQRATAAQSLQHPWL 205
>37063
          Length = 455

 Score = 37.0 bits (84), Expect = 0.016,   Method: Composition-based stats.
 Identities = 26/83 (31%), Positives = 42/83 (50%), Gaps = 10/83 (12%)
 Frame = -2

Query: 136 LKPENLLLASKLKGAAVKLADFGLA--IEVEGE---QQAWFGFAGTPGYLSPEVL----- 185
           LKPEN+L     +   +K+ DF LA  I  +G+           G+  Y++PEV+     
Sbjct: 454 LKPENILCEHLDEVVPLKICDFDLASGINCDGDGTKTPELLTPVGSAEYMAPEVVDAWVG 275

Query: 186 RKDPYGKPVDLWACGVILYILLV 208
               Y K  D+W+ G+IL +L++
Sbjct: 274 ESFSYDKRCDMWSLGIIL*VLVM 206
>16350
          Length = 1108

 Score = 37.0 bits (84), Expect = 0.020,   Method: Compositional matrix adjust.
 Identities = 16/37 (43%), Positives = 24/37 (64%), Gaps = 1/37 (2%)
 Frame = +3

Query: 236 EWDTVTPEA-KDLINKMLTINPSKRITAAEALKHPWI 271
           EWD    +A  D +  ML  +P +R TAA++L+HPW+
Sbjct: 729 EWDPKDAKAFADFLAPMLEFDPEQRATAAQSLQHPWL 839
>18996
          Length = 491

 Score = 36.6 bits (83), Expect = 0.025,   Method: Compositional matrix adjust.
 Identities = 22/79 (27%), Positives = 39/79 (49%), Gaps = 3/79 (3%)
 Frame = +2

Query: 132 VHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTP---GYLSPEVLRKD 188
           +HRDL   N+L+      + VK++DFGLA +       ++G +       + SPE +   
Sbjct: 2   IHRDLAARNILVDR----SCVKISDFGLA-QFANADGYYYGISQRDIPIKWYSPEAIETC 166

Query: 189 PYGKPVDLWACGVILYILL 207
            +    D+W+ GV L+ + 
Sbjct: 167 KFSSYSDVWSYGVTLFEMF 223
>15549
          Length = 470

 Score = 35.8 bits (81), Expect = 0.040,   Method: Compositional matrix adjust.
 Identities = 15/38 (39%), Positives = 24/38 (63%)
 Frame = -1

Query: 7   TRFTEEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKII 44
           +RF +E++  E++GKG + +V R    +  QEYA K I
Sbjct: 230 SRFADEFECIEQMGKGGYGIVFRAKNKVDEQEYAVKRI 117
>07836
          Length = 1478

 Score = 35.4 bits (80), Expect = 0.055,   Method: Compositional matrix adjust.
 Identities = 46/165 (27%), Positives = 73/165 (44%), Gaps = 26/165 (15%)
 Frame = -1

Query: 66   LLKHPNIVR-LHDSISEEG---HHYLIFDLVTGGELFEDIVAR-----EYYSEADASHCI 116
            LL+H NI+  +   I   G     +LI D    G L + +++R     E  + A ++ C 
Sbjct: 1397 LLRHENILGFIAADIKGTGSWTQLFLITDYHENGSLHDYLLSRVLDSSEMLALAHSAICG 1218

Query: 117  QQILEAVLHCHQMG------VVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQ-- 168
                 A LH    G      + HRD+K +N+L+    K     +AD GLA+    E    
Sbjct: 1217 L----AHLHIEIFGTRGKPAIAHRDIKSKNILVK---KNGTCCIADLGLAVRYISESNEV 1059

Query: 169  --AWFGFAGTPGYLSPEVLRK-------DPYGKPVDLWACGVILY 204
              A     GT  Y++PEVL         D + K  D++A G++++
Sbjct: 1058 DVAPNPRQGTKRYMAPEVLEMLLNVKNFDAF-KQADMYAFGLVMW 927
>00638
          Length = 1595

 Score = 35.4 bits (80), Expect = 0.056,   Method: Compositional matrix adjust.
 Identities = 11/32 (34%), Positives = 23/32 (71%)
 Frame = +2

Query: 107 YSEADASHCIQQILEAVLHCHQMGVVHRDLKP 138
           +++ D    + ++++A+  CH MG++HRD+KP
Sbjct: 407 FTDYDIRFYLYELMKALDFCHSMGIMHRDVKP 502
>16708
          Length = 1397

 Score = 35.0 bits (79), Expect = 0.060,   Method: Compositional matrix adjust.
 Identities = 19/47 (40%), Positives = 30/47 (63%), Gaps = 1/47 (2%)
 Frame = -1

Query: 115  CIQ-QILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLA 160
            CI  Q + A+ H H++GVVH D+K +N+L+ +       KL D+G+A
Sbjct: 1082 CIAGQXVCALEHIHELGVVHMDVKADNVLVDAH---GNCKLTDYGIA 951
>20160
          Length = 1277

 Score = 34.7 bits (78), Expect = 0.096,   Method: Compositional matrix adjust.
 Identities = 13/30 (43%), Positives = 21/30 (70%)
 Frame = +2

Query: 243 EAKDLINKMLTINPSKRITAAEALKHPWIS 272
           +A DLIN+ + ++PS R   A+ LKH W++
Sbjct: 335 DAADLINRCIALDPSTRPVLADILKHKWMT 424
>37602
          Length = 804

 Score = 33.9 bits (76), Expect = 0.15,   Method: Compositional matrix adjust.
 Identities = 28/118 (23%), Positives = 50/118 (42%), Gaps = 5/118 (4%)
 Frame = -1

Query: 65  RLLKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVL 124
           R++     V   DS       ++  +   GG + +        +E   +   ++ L+ + 
Sbjct: 354 RIVNIQTFVGYFDSYLRREKLWIAMEYCGGGSMQDIYHVTGPLTEPQIAFVCRETLKGLH 175

Query: 125 HCHQMGVVHRDLKPENLLLASKLKGAAVKLADF-----GLAIEVEGEQQAWFGFAGTP 177
           + H+ G +HRD+K  N+LL  +     VKLADF       +  V+ +   W  F G P
Sbjct: 174 YLHRRGKMHRDIKGANILLTEE---GDVKLADFWRVSSNHSHNVQKKVFHWNAFIGWP 10
>32359
          Length = 928

 Score = 33.5 bits (75), Expect = 0.21,   Method: Compositional matrix adjust.
 Identities = 22/62 (35%), Positives = 33/62 (53%), Gaps = 5/62 (8%)
 Frame = -1

Query: 19  LGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSA-----RDHQKLEREARICRLLKHPNIV 73
           +G G+F VV           Y AK+++T +L A     +D +   RE +I R L+H NIV
Sbjct: 406 IGNGSFGVV-----------YQAKLVDTSELVAIKKVLQDKRFKNRELQIMRKLEHQNIV 260

Query: 74  RL 75
           +L
Sbjct: 259 KL 254

 Score = 28.1 bits (61), Expect = 7.3,   Method: Compositional matrix adjust.
 Identities = 11/14 (78%), Positives = 13/14 (92%)
 Frame = -3

Query: 130 GVVHRDLKPENLLL 143
           GV HRD+KP+NLLL
Sbjct: 65  GVCHRDIKPQNLLL 24
>35032
          Length = 465

 Score = 33.1 bits (74), Expect = 0.26,   Method: Composition-based stats.
 Identities = 12/26 (46%), Positives = 19/26 (73%)
 Frame = +3

Query: 246 DLINKMLTINPSKRITAAEALKHPWI 271
           DL+ ++L  +PSKR+T   AL HP++
Sbjct: 147 DLVKRLLNYDPSKRLTPXXALAHPFL 224
>26009
          Length = 886

 Score = 33.1 bits (74), Expect = 0.28,   Method: Compositional matrix adjust.
 Identities = 13/33 (39%), Positives = 23/33 (69%)
 Frame = +3

Query: 111 DASHCIQQILEAVLHCHQMGVVHRDLKPENLLL 143
           +A   ++Q++ A+   H   +VHRD+KPEN+L+
Sbjct: 714 EAKSVMKQLVSALDFMHSKQLVHRDIKPENVLI 812
>20559
          Length = 430

 Score = 32.7 bits (73), Expect = 0.36,   Method: Compositional matrix adjust.
 Identities = 24/84 (28%), Positives = 41/84 (48%), Gaps = 5/84 (5%)
 Frame = -2

Query: 11  EEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQK-----LEREARICR 65
           ++Y+  E++G+G +  V +     A      +I+  K++   D  +       RE  + +
Sbjct: 375 QKYEKLEKIGEGTYGTVFK-----AKNRETHEIVALKRVRLDDDDEGVPSSALREICLLK 211

Query: 66  LLKHPNIVRLHDSISEEGHHYLIF 89
            LKH NIVRLHD +  E    L+F
Sbjct: 210 ELKHRNIVRLHDVLHSERKLTLVF 139
>17516
          Length = 453

 Score = 32.3 bits (72), Expect = 0.46,   Method: Composition-based stats.
 Identities = 16/38 (42%), Positives = 24/38 (63%), Gaps = 1/38 (2%)
 Frame = -3

Query: 173 FAGTPGYLSPEV-LRKDPYGKPVDLWACGVILYILLVG 209
            AGTP Y++PEV L+K  Y    D+++  +IL+ L  G
Sbjct: 439 LAGTPVYMAPEVLLQKGQYDMKADVYSLAIILWELWYG 326
>33586
          Length = 551

 Score = 32.3 bits (72), Expect = 0.46,   Method: Compositional matrix adjust.
 Identities = 15/48 (31%), Positives = 25/48 (52%)
 Frame = +2

Query: 72  IVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQI 119
           IV LH +   EG  YLI + + GG+LF  +     ++E D    + ++
Sbjct: 407 IVHLHYAFQTEGKLYLILEFLRGGDLFTRLSKEVMFTEEDVKFYLAEL 550
>21800
          Length = 855

 Score = 31.6 bits (70), Expect = 0.71,   Method: Compositional matrix adjust.
 Identities = 23/79 (29%), Positives = 40/79 (50%), Gaps = 7/79 (8%)
 Frame = +2

Query: 73  VRLHDSISEEG----HHYLIFDLVTGGELFEDIVAREYYSEA--DASHCIQQILEAVLHC 126
           V+L D     G    H  ++F+ V G  L + I+   Y      +    I+Q+LE + + 
Sbjct: 506 VQLLDDFKISGVNGTHVCMVFE-VLGYNLLKLIIRSNYQGIPVHNVKLIIRQVLEGLNYL 682

Query: 127 H-QMGVVHRDLKPENLLLA 144
           H +  ++H D+KPEN+L+ 
Sbjct: 683 HAKCNIIHTDIKPENILIC 739
>03106
          Length = 2384

 Score = 31.6 bits (70), Expect = 0.80,   Method: Compositional matrix adjust.
 Identities = 23/72 (31%), Positives = 33/72 (45%), Gaps = 1/72 (1%)
 Frame = +2

Query: 195 DLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEA-KDLINKMLT 253
           D+WA G + Y +     PF+       Y Q     +D PS   D  TPE    L+  ML 
Sbjct: 32  DVWAAGAVAYEIFGASNPFYSRLDSACYSQ-----HDLPSLPGD--TPEGVVRLVTSMLE 190

Query: 254 INPSKRITAAEA 265
            +P++R +A  A
Sbjct: 191 RDPAQRPSAVVA 226
>13305
          Length = 549

 Score = 30.8 bits (68), Expect = 1.4,   Method: Compositional matrix adjust.
 Identities = 15/51 (29%), Positives = 28/51 (54%), Gaps = 1/51 (1%)
 Frame = +2

Query: 179 YLSPEVLRKDPYGKPVDLWACGVILY-ILLVGYPPFWDEDQHRLYQQIKAG 228
           +++ E L  + Y    D+W+ GV+L+ I  +G  P+   D  +L+  +K G
Sbjct: 23  WMAVESLFNNTYTTQSDVWSFGVVLWEIFTLGGTPYSSTDTQQLFAFLKDG 175
>03294
          Length = 1684

 Score = 30.0 bits (66), Expect = 2.1,   Method: Compositional matrix adjust.
 Identities = 27/109 (24%), Positives = 48/109 (44%), Gaps = 25/109 (22%)
 Frame = -1

Query: 193  PVDLWACGVILYILLVGYPPF-WDEDQHRLYQQI---------------KAGAYDFPSPE 236
            PVD+W+ G I   +L+  P F  D +  +L++                 K  A++   P 
Sbjct: 1675 PVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIFRIIGTPTEQTWPEFHKLPAFNGMFPL 1496

Query: 237  W------DTVT---PEAKDLINKMLTINPSKRITAAEALKHPWISHRST 276
            W      +T+T       DLI + L  +P++RI+  + L+H +  +  T
Sbjct: 1495 WKEGKLSETLTDLDSLGLDLIERTLKCDPAQRISCKKMLQHAYFLNVDT 1349
>28494
          Length = 463

 Score = 29.6 bits (65), Expect = 2.8,   Method: Composition-based stats.
 Identities = 18/54 (33%), Positives = 24/54 (44%)
 Frame = +3

Query: 242 PEAKDLINKMLTINPSKRITAAEALKHPWISHRSTVASCMHRQETVDCLKKFNA 295
           P      NK L I+   +   A +  HP +SH ST A C  R  T+  L   +A
Sbjct: 39  PPLAPFSNKYLAISVKPQDAVAWSGVHPSLSHTSTSAFCSTRNSTMSRLSSMHA 200
>17011
          Length = 1371

 Score = 29.3 bits (64), Expect = 3.3,   Method: Compositional matrix adjust.
 Identities = 12/26 (46%), Positives = 17/26 (65%)
 Frame = +1

Query: 246 DLINKMLTINPSKRITAAEALKHPWI 271
           DLI  ++T NP  R+T   AL HP++
Sbjct: 1   DLILDVVTFNPDHRLTPDLALSHPFL 78
>14104
          Length = 573

 Score = 28.9 bits (63), Expect = 5.0,   Method: Compositional matrix adjust.
 Identities = 9/36 (25%), Positives = 22/36 (61%)
 Frame = +1

Query: 236 EWDTVTPEAKDLINKMLTINPSKRITAAEALKHPWI 271
           ++    P+A   +   L ++P++R+T  + L+HP++
Sbjct: 76  KFSNAAPQAMSFMQSCLKMDPAERLTCHQLLQHPYM 183
>32357
          Length = 625

 Score = 28.5 bits (62), Expect = 6.1,   Method: Compositional matrix adjust.
 Identities = 16/57 (28%), Positives = 33/57 (57%)
 Frame = -2

Query: 12  EYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREARICRLLK 68
           +Y+L +++G G+F  +   V   +G+E A K+    +L    H +L  E+++ R+L+
Sbjct: 435 KYRLMKKIGSGSFGEIYLGVHNTSGEEVAVKL----ELKNAKHPQLYYESKLYRVLQ 277
>32691
          Length = 295

 Score = 28.1 bits (61), Expect = 9.0,   Method: Composition-based stats.
 Identities = 14/36 (38%), Positives = 20/36 (55%)
 Frame = +1

Query: 236 EWDTVTPEAKDLINKMLTINPSKRITAAEALKHPWI 271
           +W T   E  D ++K L  NP  R TA + L+H +I
Sbjct: 82  KWST---EFIDFVSKCLVKNPENRATAVDLLQHDFI 180
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|70906479|ref|NP_001020610.1|
calcium/calmodulin-dependent protein kinase II, delta isoform 1 [Mus
musculus]
         (512 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

15910                                                                 193   1e-49
01392                                                                 127   9e-30
12721                                                                 123   1e-28
03240                                                                 109   3e-24
01060                                                                 108   6e-24
01707                                                                 108   7e-24
21079                                                                  96   3e-22
30755                                                                 100   1e-21
13592                                                                 100   2e-21
17975                                                                  99   6e-21
09606                                                                  98   1e-20
18484                                                                  97   1e-20
14126                                                                  97   2e-20
26711                                                                  93   2e-19
14420                                                                  93   3e-19
00300                                                                  89   4e-18
21433                                                                  74   3e-16
13212                                                                  80   2e-15
01966                                                                  74   2e-13
09007                                                                  73   2e-13
28638                                                                  65   4e-13
13066                                                                  72   4e-13
31885                                                                  70   2e-12
00486                                                                  69   3e-12
27405                                                                  69   3e-12
18921                                                                  69   6e-12
06405                                                                  68   9e-12
00392                                                                  68   1e-11
19761                                                                  67   2e-11
29581                                                                  66   3e-11
38560                                                                  66   3e-11
01718                                                                  66   4e-11
26560                                                                  64   1e-10
36002                                                                  63   2e-10
12786                                                                  63   3e-10
21418                                                                  62   5e-10
21808                                                                  62   5e-10
01756                                                                  62   7e-10
04591                                                                  62   7e-10
20152                                                                  62   8e-10
29590                                                                  47   1e-09
18663                                                                  57   2e-08
04138                                                                  55   5e-08
31120                                                                  55   7e-08
27274                                                                  55   9e-08
20655                                                                  54   1e-07
27546                                                                  54   1e-07
03508                                                                  53   2e-07
04852                                                                  53   3e-07
11185                                                                  52   8e-07
28157                                                                  52   8e-07
02638                                                                  51   1e-06
17300                                                                  51   1e-06
32000                                                                  50   2e-06
17722                                                                  50   2e-06
19094                                                                  50   2e-06
11780                                                                  50   2e-06
19301                                                                  49   6e-06
18481                                                                  48   7e-06
00715                                                                  47   3e-05
14116                                                                  46   3e-05
31489                                                                  46   4e-05
25019                                                                  46   4e-05
07291                                                                  45   8e-05
00394                                                                  45   9e-05
31789                                                                  45   9e-05
32957                                                                  43   4e-04
11404                                                                  42   4e-04
36481                                                                  41   0.001
01106                                                                  41   0.001
37063                                                                  41   0.001
07940                                                                  41   0.001
12672                                                                  39   0.004
23319                                                                  39   0.004
20773                                                                  39   0.005
18287                                                                  38   0.010
08294                                                                  38   0.011
18996                                                                  37   0.013
17644                                                                  37   0.014
29360                                                                  37   0.017
15549                                                                  37   0.022
16708                                                                  36   0.039
20513                                                                  36   0.047
18401                                                                  35   0.048
00638                                                                  35   0.053
20559                                                                  35   0.062
16350                                                                  35   0.063
07836                                                                  35   0.073
37602                                                                  34   0.12 
21210                                                                  34   0.16 
32359                                                                  33   0.24 
26009                                                                  33   0.30 
17516                                                                  32   0.41 
22098                                                                  32   0.48 
20160                                                                  32   0.70 
03106                                                                  32   0.78 
03294                                                                  32   0.85 
35032                                                                  32   0.90 
21800                                                                  31   1.00 
14104                                                                  31   1.3  
13305                                                                  30   1.6  
33586                                                                  30   2.1  
22005                                                                  30   3.0  
17011                                                                  29   3.6  
31232                                                                  29   5.8  
32357                                                                  28   6.5  
>15910
          Length = 1361

 Score =  193 bits (491), Expect = 1e-49,   Method: Compositional matrix adjust.
 Identities = 99/207 (47%), Positives = 135/207 (65%)
 Frame = +2

Query: 97  ELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKSKGAAVKLA 156
           ELF+ IV R  Y+E DA+  I  IL  V + H  GVVHRDLKPENLL    +  + +KLA
Sbjct: 422 ELFDRIVTRGQYTEKDAARAISDILHGVQYIHANGVVHRDLKPENLLYECMTDDSKLKLA 601

Query: 157 DFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWD 216
           DFGL+  ++ + Q      GTPGY +PEVL+ D Y   VDMW+ GVI YILL GY PF+ 
Sbjct: 602 DFGLSRIIEPEVQM-STVCGTPGYCAPEVLKGDKYTPSVDMWSVGVIAYILLCGYEPFFA 778

Query: 217 EDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPAKRITASEALKHPWICQRS 276
           E++  +Y++I  G Y F    W  ++  AKD++ K+L I+P KR+TA+EAL+ PW+   +
Sbjct: 779 ENEFEMYRKIIKGEYKFDEEYWSEISENAKDVVRKLLVIDPKKRLTATEALRLPWVKGVA 958

Query: 277 TVASMMHRQETVDCLKKFNARRKLKGA 303
           T  + M  + T++ LK+FNARRKLK A
Sbjct: 959 TKTTNM--EITMNKLKEFNARRKLKCA 1033
>01392
          Length = 1806

 Score =  127 bits (319), Expect = 9e-30,   Method: Compositional matrix adjust.
 Identities = 74/192 (38%), Positives = 100/192 (52%), Gaps = 25/192 (13%)
 Frame = -1

Query: 107  YYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKSKGAAVKLADFGLA--IEV 164
            +  E +AS  ++ I  A+   H  G+ HRDLKPEN+L         VK+ DF LA  I  
Sbjct: 1803 HLCEREASLVVRHIARALDFLHSKGIAHRDLKPENILCEHLDDVVPVKICDFDLASGISC 1624

Query: 165  QGDQQA---WFGFAGTPGYLSPEVLR-----KDPYGKPVDMWACGVILYILLVGYPPFWD 216
             GD           G+  Y++PEV+         Y K  D+W+ G+ILYI+L GYPPF+ 
Sbjct: 1623 DGDGTKTPELLTPVGSAEYMAPEVVDAWVGDSFSYDKRCDLWSLGIILYIMLCGYPPFYG 1444

Query: 217  ---ED------------QHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPAKRI 261
               ED            Q  L+  I+ G Y FPS EW +++  AKDLI  +L   P KR 
Sbjct: 1443 QCGEDCGWNRGEACHDCQDMLFNSIQDGHYKFPSQEWTSISSSAKDLIRHLLVREPRKRY 1264

Query: 262  TASEALKHPWIC 273
            +A++ LKHPWIC
Sbjct: 1263 SAADVLKHPWIC 1228
>12721
          Length = 821

 Score =  123 bits (309), Expect = 1e-28,   Method: Compositional matrix adjust.
 Identities = 77/251 (30%), Positives = 134/251 (53%), Gaps = 4/251 (1%)
 Frame = +1

Query: 17  FEELGKGAFSVVRRCMKIPT-GQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVR 75
           F ++G+G+  +V  C+     G++ A K ++ +K   R  + L  E  + R   HPNIV 
Sbjct: 103 FMKIGEGSTGIV--CIATSRDGRQMAVKKMDLRKQQRR--ELLFNEVVVMRDYHHPNIVE 270

Query: 76  LHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHR 135
           +++S       ++V + + GG L  DIV      E   +   +  L+A+   H  GV+HR
Sbjct: 271 MYNSYLVNDELWVVMEFMEGGAL-TDIVTNNRMDEVQIATVCRACLKALAFLHANGVIHR 447

Query: 136 DLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKDPYGKPV 195
           D+K +++LL+   K   VKL DFG   +V  D Q      GTP +++PEV+ + PYG  V
Sbjct: 448 DIKSDSILLSHDGK---VKLXDFGFCAQVTQDLQKRKSLVGTPYWMAPEVISRLPYGPEV 618

Query: 196 DMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT---VTPEAKDLINKM 252
           D+W+ G+++  ++   PPF++E   +  ++I+    D P P+      ++P  +  I++M
Sbjct: 619 DIWSLGIMVMEMIDAEPPFFNEPPLQAMRRIR----DMPPPKLRNTHKISPRLQGFIDRM 786

Query: 253 LTINPAKRITA 263
           L  +P +R TA
Sbjct: 787 LVRDPHQRATA 819
>03240
          Length = 1683

 Score =  109 bits (272), Expect = 3e-24,   Method: Compositional matrix adjust.
 Identities = 80/287 (27%), Positives = 126/287 (43%), Gaps = 48/287 (16%)
 Frame = -3

Query: 14   YQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARD---HQKLEREARICRLLKH 70
            ++  + LG GAF  V  C K  TG  YA K +    +  R+   H K ER+  I     +
Sbjct: 1285 FEKIKTLGVGAFGEVSLCRKNDTGMLYAMKTLRKSDVLKRNQVAHVKAERD--ILAEADN 1112

Query: 71   PNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQM 130
              +V+L+ S  +  + Y V D V GG+L   ++  E   E  A   + ++++A+   H+M
Sbjct: 1111 EWVVKLYYSFQDHNYLYFVMDYVPGGDLMGLLIRMEILDEPLARFYVAELVQAIESVHRM 932

Query: 131  GVVHRDLKPENLLLASKSKGAAVKLADFGLA-------------------------IEVQ 165
            G +HRD+KP+N+L+    +   +KL DFGL                          ++ Q
Sbjct: 931  GFIHRDIKPDNILI---DRNGHIKLTDFGLCTGFRWTHNSKYYQRDGTHARQDSMEVKCQ 761

Query: 166  GDQQAW-------------------FGFAGTPGYLSPEVL-RKDPYGKPVDMWACGVILY 205
             D+Q                         GTP Y++PEVL R   Y    D W+ GVIL+
Sbjct: 760  LDEQCQCEILKPLERRRKREQRCLAHSLVGTPNYIAPEVLSRLGGYTSVCDWWSVGVILF 581

Query: 206  ILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKM 252
             +LVG+PPF+         ++         P    ++  AKDLI ++
Sbjct: 580  EMLVGHPPFYANTPAETQYKVINWKDMLKIPRESNLSQPAKDLILRL 440
>01060
          Length = 1800

 Score =  108 bits (269), Expect = 6e-24,   Method: Compositional matrix adjust.
 Identities = 85/298 (28%), Positives = 138/298 (46%), Gaps = 37/298 (12%)
 Frame = +1

Query: 17  FEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRL 76
           F+++G+G + VV +C    TG++ A K I  +           RE  + R L+H NIV L
Sbjct: 88  FQKIGEGTYGVVYKCRHRATGRKLAMKKIRLRGSEDGVPSSAIREIAMLRELRHTNIVCL 267

Query: 77  HDSISEEGFHYLVFDLVTG-----------GELFEDIVAREYYSEADASHCIQQILEAVL 125
            D I E+   +LVF+ ++            G + +  + + Y         + QI+  + 
Sbjct: 268 EDVIMEDERLFLVFEFLSMDLKMYIDKFPEGVVLDRRLVKSY---------VFQIVTGIX 420

Query: 126 HCHQMGVVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEV 185
            CHQ  +VHRDLKP+NLL+   +   A+K+ADFG+A       +A+     T  Y +PE+
Sbjct: 421 FCHQRRIVHRDLKPQNLLI---NHTGAIKIADFGMARTFALPVRAYTHEVVTLWYRAPEI 591

Query: 186 LR-KDPYGKPVDMWACGVILYILLVGYPPF-WDEDQHRLYQQI---------------KA 228
           L     Y  PVD+W+ G I   +L+  P F  D +  +L++                 K 
Sbjct: 592 LMGASKYSTPVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIFRIIGTPTEQTWPEFHKL 771

Query: 229 GAYDFPSPEW------DTVT---PEAKDLINKMLTINPAKRITASEALKHPWICQRST 277
            A++   P W      +T+T       DLI + L  +PA+RI+  + L+H +     T
Sbjct: 772 PAFNGMFPLWKEGKLSETLTDLDSLGLDLIERTLKCDPAQRISCKKMLQHAYFLNVDT 945
>01707
          Length = 757

 Score =  108 bits (269), Expect = 7e-24,   Method: Compositional matrix adjust.
 Identities = 75/218 (34%), Positives = 108/218 (49%), Gaps = 4/218 (1%)
 Frame = +1

Query: 12  DEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLEREARICRLLKHP 71
           ++Y+   ++G+G++ VV +C    T Q  A K     +      +   RE R+ + LKHP
Sbjct: 64  EKYEKIGKIGEGSYGVVFKCRNKETSQLVAIKKFVESEDDPLIKKIAMREIRMLKQLKHP 243

Query: 72  NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMG 131
           N+VRL +    +   +LVFD V    L E         E      I Q L AV  CHQ  
Sbjct: 244 NLVRLIEVFRRKKRLHLVFDYVDHTLLNELDRYPRGLPEPMVKRIIYQTLLAVNFCHQYN 423

Query: 132 VVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKDP- 190
            +HRD+KPEN+L+   ++   VKL DFG A  + G    +  +  T  Y +PE+L  D  
Sbjct: 424 TIHRDVKPENILI---TRQGQVKLCDFGFARILTGPGDEYTDYVATRWYRAPELLVGDTQ 594

Query: 191 YGKPVDMWACGVILYILLVG---YPPFWDEDQHRLYQQ 225
           YG PVD+WA G +   LL G   +P   D DQ  L ++
Sbjct: 595 YGPPVDVWAIGCVFAELLTGQALWPGRSDVDQLHLIRK 708
>21079
          Length = 878

 Score = 95.9 bits (237), Expect(2) = 3e-22,   Method: Compositional matrix adjust.
 Identities = 57/147 (38%), Positives = 80/147 (54%), Gaps = 3/147 (2%)
 Frame = +1

Query: 70  HPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREY-YSEADASHCIQQILEAVLHCH 128
           HP ++ L D+        LV + V  GELFE ++  ++  +E D  H ++QI   V + H
Sbjct: 1   HPKLLMLWDAFEAPRTMVLVMEFVGAGELFERVIRDDFVLTERDCVHFVRQICSGVGYMH 180

Query: 129 QMGVVHRDLKPENLLLASKSKGAAVKLADFGLA-IEVQGDQ-QAWFGFAGTPGYLSPEVL 186
              ++H DLKPEN+L  S +    +K+ DFGLA     GD  Q  FG   TP +++PEV+
Sbjct: 181 TQSILHLDLKPENVLCVSDNSNQ-IKIIDFGLARFYKPGDSLQVLFG---TPEFIAPEVV 348

Query: 187 RKDPYGKPVDMWACGVILYILLVGYPP 213
             D      DMW+ GVI YILL G  P
Sbjct: 349 NYDEINFTTDMWSIGVICYILLSGLSP 429

 Score = 27.7 bits (60), Expect(2) = 3e-22,   Method: Compositional matrix adjust.
 Identities = 31/117 (26%), Positives = 52/117 (44%), Gaps = 3/117 (2%)
 Frame = +2

Query: 245 AKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKLKGAI 304
           AKD I    +    KR+T  +  KH W+ ++     +  ++   D L+ F ARRK +   
Sbjct: 521 AKDFIGNC*SREKEKRMTIEQCDKHSWLAEQDQ--RIRCKRLNTDRLRCFMARRKWQ--- 685

Query: 305 LTTMLATRNFSAAKSLLKKPDGVKINNKANVVTSPKENIP---TPALEPQTTVIHNP 358
             T  A R      SL K   G   ++  + ++S  + +P   +P L P  T + +P
Sbjct: 686 -KTGNAIRALGRMASLQKMLIGGSSHSNNSSLSSIPDTVPAVHSPVLSPSPTPLXHP 853
>30755
          Length = 1137

 Score =  100 bits (250), Expect = 1e-21,   Method: Compositional matrix adjust.
 Identities = 58/160 (36%), Positives = 85/160 (53%), Gaps = 5/160 (3%)
 Frame = +2

Query: 119 QILEAVLHCHQMGVVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTP 178
           +I+ A+ + H  G+++RDLK ENLLL    K   +K+ADFGL  E     +    F GTP
Sbjct: 56  EIISALGYLHSQGIIYRDLKLENLLL---DKDGHIKVADFGLCKEDITYGRTTKTFCGTP 226

Query: 179 GYLSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEW 238
            YL+PEVL  + YG+ VD W  GV++Y ++ G  PF++ D   L+  I      FP    
Sbjct: 227 EYLAPEVLDDNDYGRAVDWWGTGVVMYEMICGRLPFYNRDHDVLFTLILVEDVKFPR--- 397

Query: 239 DTVTPEAKDLINKMLTINPAKRITAS-----EALKHPWIC 273
             +T EAK L++ +L  +P  R+        E   HP+  
Sbjct: 398 -NITDEAKSLLSGLLAKDPRNRLGGGQDDVKEIQAHPFFA 514
>13592
          Length = 980

 Score =  100 bits (248), Expect = 2e-21,   Method: Compositional matrix adjust.
 Identities = 77/264 (29%), Positives = 128/264 (48%), Gaps = 11/264 (4%)
 Frame = +2

Query: 19  ELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHD 78
           ++G+G F  V   +   TG+  A K I  +    R  + +  E +I   +KH N+VR + 
Sbjct: 5   KIGQGRFGKVYTAVNNNTGELMAMKEIAIQPGETRALKNVAEELKILEGIKHKNLVRYY- 181

Query: 79  SISEEGFHYLVF-DLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDL 137
            I       L+F +L + G L   +       EA +     Q+L  V   H+ G+VHRD+
Sbjct: 182 GIEVHREELLIFMELCSEGTLESLVELTGGLPEALSRRFTAQLLSGVAELHKHGIVHRDI 361

Query: 138 KPENLLLASKSKGAAVKLADFGLAIEVQ------GDQQAWFGFAGTPGYLSPEVLRK--- 188
           K  N+ L   S   ++KL DFG A+++Q      G+ Q   G+ GT  Y++PEV  K   
Sbjct: 362 KTANIFLVDGSN--SLKLGDFGSAVKIQAHTTVPGELQ---GYVGTQAYMAPEVFTKTNS 526

Query: 189 DPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFP-SPEWDTVTPEAKD 247
           D +G+  D+W+ G ++  +  G  P W +         K G  + P +PE  +++ E  D
Sbjct: 527 DGHGRLADIWSVGCVVVEMASGKRP-WAQFDSNFQIMFKVGMGEKPQAPE--SLSQEGHD 697

Query: 248 LINKMLTINPAKRITASEALKHPW 271
            I+  L  +P +R++A E L+  +
Sbjct: 698 FIDHCLQHDPKQRLSAIELLEQNF 769
>17975
          Length = 449

 Score = 98.6 bits (244), Expect = 6e-21,   Method: Composition-based stats.
 Identities = 52/138 (37%), Positives = 83/138 (60%), Gaps = 1/138 (0%)
 Frame = +3

Query: 25  FSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEG 84
           F+VV+    + TG++ A K+I+  KL       L +E R  +L++HPN+VRL++ I  + 
Sbjct: 6   FAVVKLARHVFTGEKVAVKVIDKTKLDEVSRSHLFQEVRCMKLVQHPNVVRLYEVIDTQT 185

Query: 85  FHYLVFDLVTGGELFEDIVARE-YYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLL 143
             YL+ +L  GG++++ I+       E  A    +QI+EA+ +CH++ VVHRDLKPEN++
Sbjct: 186 KLYLILELGDGGDMYDYIMRHSGGLEEKLAKRYFRQIVEAISYCHKLHVVHRDLKPENVV 365

Query: 144 LASKSKGAAVKLADFGLA 161
              K     VKL DFG +
Sbjct: 366 FFEKP--GLVKLTDFGFS 413
>09606
          Length = 1300

 Score = 97.8 bits (242), Expect = 1e-20,   Method: Compositional matrix adjust.
 Identities = 70/285 (24%), Positives = 131/285 (45%), Gaps = 27/285 (9%)
 Frame = -3

Query: 12   DEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLEREARICRLLKHP 71
            + + L+EELGKG  S++ +  +  T    A   I   K       ++    R+   + HP
Sbjct: 1115 ENFVLYEELGKGEHSIIYKGRRKGTINFVAIHCIEKCK-----RPEVTNTVRMTHDISHP 951

Query: 72   NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYY-SEADASHCIQQILEAVLHCHQM 130
            N+V+ H+        +LV +L TGG L  DI+A++++  E         ++  + + H +
Sbjct: 950  NVVQFHEWYETSNHLWLVVELCTGGSL-ADILAQDHHLPETSIRDFGIHLVTGLHYIHSL 774

Query: 131  GVVHRDLKPENLLLASKSKGAAVKLADFGLA-IEVQGDQQAWFGFA-------------- 175
            G++  DL+P  +LL +      +K ADFGL+ +E +  ++ +F FA              
Sbjct: 773  GILFHDLRPSKVLLDTS---GVLKFADFGLSKVEGENLEELFFKFAEAGDQWNIQSAEEM 603

Query: 176  -------GTPGYLSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKA 228
                   G+P Y++PEV +        D+WA G + Y +  G+PPF  E       ++  
Sbjct: 602  MKQVPTSGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFSGHPPFLGETYDITKDKVLN 423

Query: 229  GAYDFPSPEWDTV----TPEAKDLINKMLTINPAKRITASEALKH 269
              +  P  +   +    +PE  +L+  +L  +  +R++ +  +KH
Sbjct: 422  KEFPLPKVKGSRLSAKPSPEFLNLLESLLQKDSTRRLSWASLVKH 288
>18484
          Length = 635

 Score = 97.1 bits (240), Expect = 1e-20,   Method: Compositional matrix adjust.
 Identities = 53/154 (34%), Positives = 81/154 (52%)
 Frame = +1

Query: 108 YSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGD 167
           + E  A+    +I   +   H  G+++RDLK +N++L S+     +K+ADFG+  E    
Sbjct: 34  FKEPVAAFYAAEIAVGLFFLHDQGIIYRDLKLDNVMLDSEGH---IKIADFGMCKEGMTG 204

Query: 168 QQAWFGFAGTPGYLSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIK 227
                 F GTP Y++PE++   PY K VD WA GV+L+ +L G PPF  ED+  L+  I 
Sbjct: 205 DATTRTFCGTPDYIAPEIVLYQPYSKSVDWWAYGVLLFEMLAGQPPFDGEDEDELFSSIT 384

Query: 228 AGAYDFPSPEWDTVTPEAKDLINKMLTINPAKRI 261
                +P      ++ EA  L   +L  NP KR+
Sbjct: 385 DHNVSYPK----AMSREAVSLCKGLLMKNPTKRL 474
>14126
          Length = 1265

 Score = 97.1 bits (240), Expect = 2e-20,   Method: Compositional matrix adjust.
 Identities = 92/310 (29%), Positives = 133/310 (42%), Gaps = 50/310 (16%)
 Frame = +3

Query: 13  EYQLFEELGKGAFSVVRRCMKIPTGQEYAA-KIINTKKLSARDHQKLEREARICRLLK-- 69
           +Y+    +G GA+  V +   +    E+ A K I              RE  + + L+  
Sbjct: 192 KYEEVAVIGNGAYGTVYKARDLRNQGEFVAMKRIRLNNTEEGMPMMAIREISMLKQLEQY 371

Query: 70  -HPNIVRL----HDSISEEG------FHYLVFDLVT----------GGELFEDIVAREYY 108
            HPN+VRL    H++I++        F Y+  DL T          G +  +D++     
Sbjct: 372 EHPNVVRLLDVSHNTITDREIRLNLVFEYIEHDLATYLAKCPSPGLGPDRIKDLML---- 539

Query: 109 SEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQ 168
                     Q+L  V   H   +VHRDLKP+NLL+   SK   +KLADFGLA  +    
Sbjct: 540 ----------QLLNGVDFLHSNRIVHRDLKPQNLLI---SKDGRLKLADFGLA-RIYSFH 677

Query: 169 QAWFGFAGTPGYLSPEVLRKDPYGKPVDMWACGVILYIL--------------------- 207
            A      T  Y SPEVL +  YG  VD+W+CG I   L                     
Sbjct: 678 MALTTVVVTLWYRSPEVLMQAEYGTSVDIWSCGCIFAELFTRRALFKGSSEFDQLKKIFE 857

Query: 208 LVGYPPF--WDE--DQHR-LYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPAKRIT 262
           ++G PP   W E    HR  ++           PE D   P+AKDL+ KML     +RI+
Sbjct: 858 VIGLPPAGDWPEGVSVHRNSFRPTPPVPLQTLVPEMD---PQAKDLMEKMLVFKSGRRIS 1028

Query: 263 ASEALKHPWI 272
           + E+L HP++
Sbjct: 1029SRESLLHPYL 1058
>26711
          Length = 405

 Score = 93.2 bits (230), Expect = 2e-19,   Method: Composition-based stats.
 Identities = 52/134 (38%), Positives = 75/134 (55%), Gaps = 1/134 (0%)
 Frame = -2

Query: 117 IQQILEAVLHCHQMGVVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAG 176
           ++Q+L+ + H H  GVVH DLKP NLLL S  K  +V+L DFGLA ++   Q+ +    G
Sbjct: 398 VKQVLDILQHVHAQGVVHMDLKPSNLLL-SGDKLDSVQLIDFGLARKLYPPQETFLNH-G 225

Query: 177 TPGYLSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFP-S 235
           TPG+ SPE L   P     D+W  GV+ YILL G  PF  +      ++ +   + F   
Sbjct: 224 TPGFTSPEALDVKPISTASDVWGVGVLAYILLSGQSPFQADSATESLKKTQTCDWSFDVC 45

Query: 236 PEWDTVTPEAKDLI 249
           P +  ++ +AKD I
Sbjct: 44  PSFSNMSQDAKDFI 3
>14420
          Length = 528

 Score = 92.8 bits (229), Expect = 3e-19,   Method: Compositional matrix adjust.
 Identities = 57/178 (32%), Positives = 96/178 (53%), Gaps = 3/178 (1%)
 Frame = +2

Query: 47  TKKLSARDHQKLE-REARICRLLKHPNIVRLHDS--ISEEGFHYLVFDLVTGGELFEDIV 103
           T  LS +  ++L   E  + R  ++PNIV   DS  + EE   ++V + + GG L  D+V
Sbjct: 5   TMNLSQQPKKELIINEILVMRENQNPNIVNYLDSYLVGEE--LWVVMEFLAGGSL-TDVV 175

Query: 104 AREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKSKGAAVKLADFGLAIE 163
                 E   +   ++ L+A+   H+  V+HRD+K +N+LL       +VKL DFG   +
Sbjct: 176 TETCMDEGQIAAVCRECLQALEFLHENQVIHRDIKSDNILLGMD---GSVKLTDFGFCAQ 346

Query: 164 VQGDQQAWFGFAGTPGYLSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHR 221
           +  +Q       GTP +++PEV+ +  YG  VD+W+ GV+   ++ G PP+ +E+  R
Sbjct: 347 LSPEQSKRSTMVGTPYWMAPEVVTRKQYGPTVDIWSLGVMCIEMIEGEPPYLNENPLR 520
>00300
          Length = 2318

 Score = 89.0 bits (219), Expect = 4e-18,   Method: Compositional matrix adjust.
 Identities = 72/273 (26%), Positives = 130/273 (47%), Gaps = 10/273 (3%)
 Frame = -1

Query: 9    RFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER---EARIC 65
            R    +Q   ++G+G F  V   + + TG+  A K +   K    D Q+L     E +I 
Sbjct: 1667 RVNFRWQRGNKIGEGQFGKVYTAVNMSTGELMALKEM---KFQPNDLQQLREMCDEIKIF 1497

Query: 66   RLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVL 125
              ++H N+V+ +     +    +  +    G + E   A+    E       ++I+ AV 
Sbjct: 1496 EGIQHENLVKYYGVEVHKDEMLMFMEYCDTGTIEE--AAKMGLPEYLIRRYTREIVLAVN 1323

Query: 126  HCHQMGVVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQA---WFGFAGTPGYLS 182
            H H+  +VHRD+K  N+ L S      VKL DFG +++++        +    GT  Y++
Sbjct: 1322 HLHENSIVHRDIKGANIFLTSNGH---VKLGDFGCSVKLKSHTTMPGEFHNLVGTTAYMA 1152

Query: 183  PEVLRKDP---YGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQI-KAGAYDFPSPEW 238
            PEV  ++    YG+  D+W+ G ++  +  G  P+ D D +  YQ + K G    P+   
Sbjct: 1151 PEVFTQNDQGGYGRAADIWSLGCVVIEMATGKRPWHDLDNN--YQIMYKVGIGHKPAVP- 981

Query: 239  DTVTPEAKDLINKMLTINPAKRITASEALKHPW 271
            D+++ E K  ++ ++  +PA+R  AS+ L H +
Sbjct: 980  DSLSVEGKHFLDLIMCHDPAQRALASQLLDHTF 882
>21433
          Length = 590

 Score = 74.3 bits (181), Expect(2) = 3e-16,   Method: Compositional matrix adjust.
 Identities = 47/142 (33%), Positives = 70/142 (49%), Gaps = 5/142 (3%)
 Frame = +2

Query: 117 IQQILEAVLHCHQMGVVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAG 176
           I Q+  A+ +CH   V+HRD+KPEN           +K+ADFG ++     ++      G
Sbjct: 185 IYQLSSALEYCHYRKVIHRDIKPEN---LLLGLKGDLKIADFGWSVHAPSSRRT--TMCG 349

Query: 177 TPGYLSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSP 236
           T  YL PE++    + + VD+W+ GV+ Y  LVG PP          +          SP
Sbjct: 350 TLDYLPPEMVEGKTHDENVDLWSLGVLCYEFLVGTPPL---------RPSPTRPPTPASP 502

Query: 237 EWDT-----VTPEAKDLINKML 253
            W +     VTP A+DLI+K+L
Sbjct: 503 RWTSGSPSIVTPGARDLISKLL 568

 Score = 28.9 bits (63), Expect(2) = 3e-16,   Method: Compositional matrix adjust.
 Identities = 14/47 (29%), Positives = 26/47 (55%)
 Frame = +3

Query: 56  QKLEREARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDI 102
            +L RE  I   L+H NI+R+     ++   YL+ +    GEL++++
Sbjct: 3   HQLRREIEIQSHLRHDNILRMFGYFHDKTRVYLILEFAPKGELYKEL 143
>13212
          Length = 1067

 Score = 80.5 bits (197), Expect = 2e-15,   Method: Compositional matrix adjust.
 Identities = 66/199 (33%), Positives = 101/199 (50%), Gaps = 10/199 (5%)
 Frame = -1

Query: 89   VFDLVTGGELFEDIVAREY-YSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASK 147
            VF ++  G L   +V  E   +EA   +   ++  A+   H+  V+HRD+K  N+LL   
Sbjct: 1049 VFRVLWWGALDSIMVDLEKPMTEAQICYVCHEMCMALDFLHRHHVIHRDIKAGNVLL--- 879

Query: 148  SKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEV-----LRKDPYGKPVDMWACGV 202
            +    VKLADFG++ +    QQ    F GTP +++PEV     L+  PY    D+W+ GV
Sbjct: 878  TIDGEVKLADFGVSAKNTQTQQKRDTFIGTPYWMAPEVVLCETLKDTPYDFKADIWSLGV 699

Query: 203  ILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPE----WDTVTPEAKDLINKMLTINPA 258
             L       PP  +++ H +   IK    D P+ E    W  +    KD I K L  +P 
Sbjct: 698  TLIEFAQIEPP--NKEMHPMRVLIKIHKSDPPTLEKPKKWTKL---FKDFIAKCLVKDPN 534

Query: 259  KRITASEALKHPWICQRST 277
             R TA+E L+HP++ +R+T
Sbjct: 533  LRPTAAELLEHPFM-KRAT 480
>01966
          Length = 1735

 Score = 73.6 bits (179), Expect = 2e-13,   Method: Compositional matrix adjust.
 Identities = 59/190 (31%), Positives = 88/190 (46%), Gaps = 14/190 (7%)
 Frame = -1

Query: 28   VRR---CMKIPTGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEG 84
            VRR   C    TG++ A K I  +           RE  + R L+H NIV L D I E+ 
Sbjct: 1672 VRRGL*CRHRATGRKLAMKKIRLRGSEDGVPSSAIREIAMLRELRHTNIVCLEDVIMEDE 1493

Query: 85   FHYLVFDLVTG-----------GELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVV 133
              +LVF+ ++            G + +  + + Y         + QI+  +  CHQ  +V
Sbjct: 1492 RLFLVFEFLSMDLKMYIDKFPEGVVLDRRLVKSY---------VFQIVTGINFCHQRRIV 1340

Query: 134  HRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKDPYGK 193
            HRDLKP+NLL+   +   A+K+ADFG+A       +A+     T  Y +PE+L   P   
Sbjct: 1339 HRDLKPQNLLI---NHTGAIKIADFGMARTFALPVRAYTHEVVTLWYRAPEIL-MGPQST 1172

Query: 194  PVDMWACGVI 203
            P   W CG +
Sbjct: 1171 P-PXWTCGAL 1145

 Score = 33.1 bits (74), Expect = 0.26,   Method: Compositional matrix adjust.
 Identities = 29/112 (25%), Positives = 48/112 (42%), Gaps = 25/112 (22%)
 Frame = -3

Query: 191  YGKPVDMWACGVILYILLVGYPPF-WDEDQHRLYQQI---------------KAGAYDFP 234
            Y  PVD+W+ G I   +L+  P F  D +  +L++                 K  A++  
Sbjct: 1175 YSTPVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIFRIIGTPTEQTWPEFHKLPAFNGM 996

Query: 235  SPEW------DTVT---PEAKDLINKMLTINPAKRITASEALKHPWICQRST 277
             P W      +T+T       DLI + L  +PA+RI+  + L+H +     T
Sbjct: 995  FPLWKEGKLSETLTDLDSLGLDLIERTLKCDPAQRISCKKMLQHAYFLNVDT 840
>09007
          Length = 1440

 Score = 73.2 bits (178), Expect = 2e-13,   Method: Compositional matrix adjust.
 Identities = 61/230 (26%), Positives = 108/230 (46%), Gaps = 13/230 (5%)
 Frame = -1

Query: 12  DEYQLFEELGKGAFSVVRRCMKIPTGQE---YAAKIINTKKLSARDHQKLEREARICRLL 68
           D   L + LG+G F  VR+ +      E    A K ++  K+  +D Q+  +E  I ++L
Sbjct: 879 DCVALSKSLGQGHFGTVRQAIWTAESGEKVQVAVKCLSKDKIH-KDGQEFLKETAIMQML 703

Query: 69  KHPNIVRLHDSISEEGFH-YLVFDLVTGGELFE---DIVAREYYSEADASHCIQQILEAV 124
            H NIVR++  + + G    LV +L     L E   ++ AR  +S        QQ+ + +
Sbjct: 702 DHENIVRVYGVVMDNGADIMLVTELAPMRSLLECVKEVSARVDFSVPRLCDFSQQVCDGM 523

Query: 125 LHCHQMGVVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAW-----FGFAGTPG 179
            +     +VHRDL   N+LL SKSK   VK++D G++  +   ++ +             
Sbjct: 522 SYLESKRLVHRDLAARNILLFSKSK---VKISDVGVSGALGAGKEYYQSQQTIHLQNAVA 352

Query: 180 YLSPEVLRKDPYGKPVDMWACGVILYILLV-GYPPFWDEDQHRLYQQIKA 228
           + +PE  R   +    D+WA GV+L+     G+ P+   +  ++ + + A
Sbjct: 351 WCAPESFRNLCFSSASDVWAFGVLLWEFFTHGFQPWAGLNGQQIMEAVDA 202
>28638
          Length = 1458

 Score = 65.5 bits (158), Expect(2) = 4e-13,   Method: Compositional matrix adjust.
 Identities = 38/99 (38%), Positives = 57/99 (57%), Gaps = 2/99 (2%)
 Frame = -1

Query: 118 QQILEAVLHCH--QMGVVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFA 175
           QQ+  A+L     +M ++H DLKPEN+LL +  K +A+K+ DFG + ++    Q  + + 
Sbjct: 816 QQLCTALLFLATPEMNIIHCDLKPENILLCNP-KRSAIKIVDFGSSCQLG---QRIYQYI 649

Query: 176 GTPGYLSPEVLRKDPYGKPVDMWACGVILYILLVGYPPF 214
            +  Y SPEVL   PY   +DMW+ G IL  +  G PP 
Sbjct: 648 QSRFYRSPEVLLGVPYDLAIDMWSLGCILVEMHTGEPPL 532

 Score = 27.3 bits (59), Expect(2) = 4e-13,   Method: Compositional matrix adjust.
 Identities = 24/97 (24%), Positives = 41/97 (42%), Gaps = 12/97 (12%)
 Frame = -3

Query: 9    RFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKK------------LSARDHQ 56
            ++ D Y++   +GKG+F  V +       ++ A KII  KK            L   +  
Sbjct: 1156 KWLDRYEIDSLIGKGSFGQVVKAYDHGDQEQVAIKIIKNKKPFLNQAQIEVKLLELMNRH 977

Query: 57   KLEREARICRLLKHPNIVRLHDSISEEGFHYLVFDLV 93
              +    I RL +H  + R H  +  E   Y ++DL+
Sbjct: 976  DADNXYYIVRLKRHF-MFRNHLCLVFELLSYNLYDLL 869
>13066
          Length = 551

 Score = 72.4 bits (176), Expect = 4e-13,   Method: Compositional matrix adjust.
 Identities = 52/166 (31%), Positives = 78/166 (46%), Gaps = 5/166 (3%)
 Frame = +3

Query: 41  AAKIINTKKLSARDHQKL-EREARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELF 99
           A KII+ +K      +K   RE  +   L HP I+++H  +     +++       G+L 
Sbjct: 63  ACKIIDKEKAPVDFVEKFFPRELDLLTKLDHPYIIQIHSILQRXPKNFIFMRFAERGDLL 242

Query: 100 EDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKSKGAAVKLADFG 159
             I    +  E  A     Q+  A+ + H   V HRDLK EN+LL+S      VKLADFG
Sbjct: 243 TYIQEVGFVKEKQAKIWFYQMTTALNYLHSYDVAHRDLKCENILLSSHFN---VKLADFG 413

Query: 160 LA---IEVQGDQQAWFGFAGTPGYLSPEVLRKDPYG-KPVDMWACG 201
            A   I   G++     + G+  Y +PE++   PY  K  D W+ G
Sbjct: 414 FACACITESGEKYMSRTYCGSAAYAAPEIVYGAPYAPKVADAWSLG 551
>31885
          Length = 529

 Score = 70.1 bits (170), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 47/152 (30%), Positives = 76/152 (50%), Gaps = 5/152 (3%)
 Frame = -2

Query: 68  LKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHC 127
           L HP +V L  +  +E   ++V DL  GG+L   +     + E      + Q+   + + 
Sbjct: 501 LDHPFLVNLWYAFQDEEDLFMVVDLFLGGDLRYHMQQEVSFREDCVKFYLCQLALVLDYL 322

Query: 128 HQMGVVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVL- 186
               +VHRD+KP+N+LL  +       + DF +A +++ D+ A    +GT  Y++PEV  
Sbjct: 321 RSQKIVHRDIKPDNILLDEQGH---CHVTDFNIATQLEDDELA-TSTSGTRPYMAPEVYG 154

Query: 187 ----RKDPYGKPVDMWACGVILYILLVGYPPF 214
                +  YG PVD W+ GV L+ LL    PF
Sbjct: 153 VAINERRGYGFPVDWWSLGVSLFELLKKRRPF 58
>00486
          Length = 797

 Score = 69.3 bits (168), Expect = 3e-12,   Method: Compositional matrix adjust.
 Identities = 34/88 (38%), Positives = 53/88 (60%)
 Frame = -2

Query: 174 FAGTPGYLSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDF 233
           F GT  Y++PE+L +  +GK VD W+ G ++Y +L G PPF  E++ +   +I  G  + 
Sbjct: 778 FCGTIEYMAPEILTRTGHGKAVDWWSLGALMYDMLTGSPPFTAENRKKTIDKILKGKLNL 599

Query: 234 PSPEWDTVTPEAKDLINKMLTINPAKRI 261
           P      +T EA+ LI K+L  NPA+R+
Sbjct: 598 PP----YLTNEARGLIKKLLRKNPAERL 527
>27405
          Length = 532

 Score = 69.3 bits (168), Expect = 3e-12,   Method: Compositional matrix adjust.
 Identities = 49/170 (28%), Positives = 80/170 (47%), Gaps = 5/170 (2%)
 Frame = -3

Query: 24  AFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLEREARICRLL-----KHPNIVRLHD 78
            F  V  C K  TG+ YA K ++ K++  +  + L    RI   L       P IV +  
Sbjct: 530 GFGEVYGCRKADTGKMYAMKCLDKKRIKMKGGETLALNERIMLSLVSTGEGSPFIVCMTY 351

Query: 79  SISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLK 138
           +         + DL+ GG+L   +     ++E +      +++  + H H   VV+RDLK
Sbjct: 350 AFQTPEKLCFILDLMNGGDLHYHLSQHGVFTEKEVRFYAAEVMLGLEHMHSRFVVYRDLK 171

Query: 139 PENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRK 188
           P N+LL    +   V+++D GLA +    ++      GT GY++PEVL K
Sbjct: 170 PANILL---DENGHVRISDLGLACDFS--KKKPHASVGTHGYMAPEVLMK 36
>18921
          Length = 697

 Score = 68.6 bits (166), Expect = 6e-12,   Method: Compositional matrix adjust.
 Identities = 50/203 (24%), Positives = 97/203 (47%), Gaps = 1/203 (0%)
 Frame = +2

Query: 12  DEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLEREARICRLLKHP 71
           D + +  +LG+G++  V + +   TGQ  A K +        D Q++ +E  I +     
Sbjct: 29  DVFDILGKLGEGSYGSVFKSLHKETGQVLAIKQVPVDT----DLQEIIKEISIMQQCDSK 196

Query: 72  NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAR-EYYSEADASHCIQQILEAVLHCHQM 130
            IV+ + S  +    ++V +    G + + +  R +   E + +  +   L+ + + H  
Sbjct: 197 YIVKYYGSYFKNTDLWIVMEYCGAGSVSDIMRLRNKTLVEREIATILYYTLKGLXYLHSR 376

Query: 131 GVVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKDP 190
             +HRD+K  N+LL ++      KLADFG+A ++           GTP +++PEV+++  
Sbjct: 377 RKIHRDIKAGNILLNNEGHA---KLADFGVAGQLTDTMAKRNTVIGTPYWMAPEVIQEIG 547

Query: 191 YGKPVDMWACGVILYILLVGYPP 213
           Y    D+W+ G+    +  G PP
Sbjct: 548 YDCVADIWSLGITALEMAEGKPP 616
>06405
          Length = 1965

 Score = 67.8 bits (164), Expect = 9e-12,   Method: Compositional matrix adjust.
 Identities = 59/221 (26%), Positives = 97/221 (43%), Gaps = 4/221 (1%)
 Frame = +1

Query: 13  EYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPN 72
           E  +   LG G +  V   M     +  A K +    ++  D      EA I + +KHPN
Sbjct: 262 EIAMKHRLGGGQYGDVYEAMWKRYNKIVAVKTLKEDTMALND---FLEEAAIMKEMKHPN 432

Query: 73  IVRLHDSISEEGFHYLVFDLVTGGELFEDIVA--REYYSEADASHCIQQILEAVLHCHQM 130
           +V+L    + E   Y+V + +  G L + + +  RE        +   QI   + +    
Sbjct: 433 LVQLLGVCTREPPFYIVTEFMPHGNLLDYLRSSTREENGPTALMYMATQIASGMAYLETK 612

Query: 131 GVVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQ-QAWFGFAGTPGYLSPEVLRKD 189
             +HRDL   N L+A  +    VK+ADFGLA  ++ D   A  G      + +PE L  +
Sbjct: 613 NFIHRDLAARNCLVADSN---MVKVADFGLARLMKDDTYTAHIGAKFPIKWTAPEGLAFN 783

Query: 190 PYGKPVDMWACGVILYILLV-GYPPFWDEDQHRLYQQIKAG 229
            +    D+WA GV+L+ L   G  P+   +   +Y  ++ G
Sbjct: 784 RFSTRSDIWAFGVLLWELATYGMSPYPGVELTEVYHLLERG 906
>00392
          Length = 668

 Score = 67.8 bits (164), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 55/214 (25%), Positives = 105/214 (49%), Gaps = 8/214 (3%)
 Frame = +3

Query: 45  INTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGFH-----YLVFDLVTGGELF 99
           +  KK +  + Q+ + EA + + L+HPNIVR  D   E          LV +L+T G L 
Sbjct: 33  LQDKKWNKAERQRFKEEAEMLKELQHPNIVRFFDYWEEHNHRNRKVIILVTELMTSGTLK 212

Query: 100 EDIVAREYYSEADASHCIQQILEAV--LHCHQMGVVHRDLKPENLLLASKSKGAAVKLAD 157
             +   +  +     +  +Q+L+ +  LH     V+HRDLK +N+ +   +   +VK+ D
Sbjct: 213 TYLKRFKKPNVKILKNWCRQVLKGLYFLHTRTPPVIHRDLKCDNIFITGPT--GSVKIGD 386

Query: 158 FGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWD- 216
            GLA     +Q       GTP +++PE + ++ Y + VD++A G+ +  +     P+ + 
Sbjct: 387 LGLA--TLKNQSFAKSVIGTPEFMAPE-MYEEHYDEAVDVYAFGMCMLEMASSEYPYSEC 557

Query: 217 EDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLIN 250
            +  ++Y+++ +G    P         E +D+I+
Sbjct: 558 SNAAQIYKRVTSGV--LPEALDKVAITEIRDIIH 653
>19761
          Length = 473

 Score = 67.0 bits (162), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 44/130 (33%), Positives = 65/130 (50%)
 Frame = -3

Query: 125 LHCHQMGVVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPE 184
           +H H   ++HRDLKP+N+ +  K     V+L D GLA ++ G         GT  YLSPE
Sbjct: 375 MHTHTPVILHRDLKPQNIYVTEKGD---VRLGDLGLARKLTGPADFATSQVGTIMYLSPE 205

Query: 185 VLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPE 244
           +L + PY    D+W+ G + Y  + G     +     L  Q+  G    P P  D  + E
Sbjct: 204 ILSQQPYNSKSDIWSLGCVFYD-ITGKKGSDEMGVMFLLVQVMGGR-KLPLP--DHYSQE 37

Query: 245 AKDLINKMLT 254
            +D I++MLT
Sbjct: 36  FRDTISRMLT 7
>29581
          Length = 1278

 Score = 66.2 bits (160), Expect = 3e-11,   Method: Compositional matrix adjust.
 Identities = 65/237 (27%), Positives = 105/237 (44%), Gaps = 32/237 (13%)
 Frame = -2

Query: 68   LKHPNIVRLHDSISEEGFH--YLVFDLVTG--GELFEDIVAREYYSEADASHCIQQILEA 123
            L+H NIV+L + +  +     +LV +        L +++ A   +SE+     + Q+L+ 
Sbjct: 1184 LRHQNIVQLQEVVVGKSLDSLFLVMEYCEQDLASLLDNMPAP--FSESQVKCIVLQLLKG 1011

Query: 124  VLHCHQMGVVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSP 183
            + + H+  ++HRDLK  NLL+  K     VK+ADFGLA      Q+       T  Y +P
Sbjct: 1010 LRYLHEAFIIHRDLKVSNLLMTDK---GCVKIADFGLARNYGKPQKPMTPKVVTLWYRAP 840

Query: 184  EVL-RKDPYGKPVDMWACGVILYILLVGYPPFW----DEDQHRLYQQ--------IKAGA 230
            E+L     +   +DMW+ G IL  LL G+ P      D  Q  L  +        I  G 
Sbjct: 839  ELLFGSKTHSTAIDMWSAGCILGELL-GHKPLMPGRSDLQQIELIMELLGTPNDTIWPGF 663

Query: 231  YDFPSPEWDTVTPEAKD---------------LINKMLTINPAKRITASEALKHPWI 272
               P+ E  T+  +  +               L+N +   +P KR TA + L+H + 
Sbjct: 662  SQLPAFEQFTLKKQPYNNLRHTFPWLSESGIRLLNGLFMYHPQKRATAEDCLEHSYF 492
>38560
          Length = 479

 Score = 65.9 bits (159), Expect = 3e-11,   Method: Compositional matrix adjust.
 Identities = 44/121 (36%), Positives = 61/121 (50%), Gaps = 5/121 (4%)
 Frame = -3

Query: 176 GTPGYLSPEVLRKDPY-GKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFP 234
           G+P Y +PE++    Y G   D+W+ GV+LY LL GY PF DE    L Q+ +    +  
Sbjct: 399 GSPAYAAPELISGLEYLGSEADIWSMGVLLYALLCGYLPFDDEKXSHL*QKNQKRKDEV- 223

Query: 235 SPEWDTVTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTV----ASMMHRQETVDC 290
            PEW  ++ +   L+  ML  +P+ RIT    L H W+ Q   V    AS   R    DC
Sbjct: 222 -PEW--LSEDTTKLLEGMLQTDPSHRITIRRLLDHHWLNQGFNVPVEWASKYKRTLDEDC 52

Query: 291 L 291
           L
Sbjct: 51  L 49
>01718
          Length = 959

 Score = 65.9 bits (159), Expect = 4e-11,   Method: Compositional matrix adjust.
 Identities = 58/208 (27%), Positives = 104/208 (50%), Gaps = 6/208 (2%)
 Frame = +3

Query: 3   STTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLEREA 62
           + +  TR  D   + E++G G FS V +     TGQ  A K+ NT  +++  H  L RE 
Sbjct: 126 AVSALTRLDDF--ICEKIGAGFFSEVFKVTHRITGQVMALKM-NT--MTSNRHNML-REV 287

Query: 63  RICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQIL- 121
           ++   L+H NI+R       EG  + + + +  G L + +  ++   E   +  IQ  L 
Sbjct: 288 QLLNRLQHANILRFMGVCVHEGQLHALTEYIPSGNLEQLLEKKD--EELPWTQRIQLTLG 461

Query: 122 --EAVLHCHQMGVVHRDLKPENLLLASK-SKGAAVKLADFGLAIEVQG--DQQAWFGFAG 176
               + + H    +HRDL  +N+L+  + + G    +ADFGLA ++    D++      G
Sbjct: 462 LARGLDYLHSTRFIHRDLTSKNILIRREDNHGYHAVIADFGLATKIPDPLDKEK-LPTVG 638

Query: 177 TPGYLSPEVLRKDPYGKPVDMWACGVIL 204
           +P +++PEVL    Y +  D+++ G+I+
Sbjct: 639 SPYWMAPEVLNGHFYNERADLFSVGIIM 722
>26560
          Length = 398

 Score = 64.3 bits (155), Expect = 1e-10,   Method: Composition-based stats.
 Identities = 38/113 (33%), Positives = 61/113 (53%), Gaps = 1/113 (0%)
 Frame = -1

Query: 108 YSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGD 167
           ++E +      +++  + H H   VV+RDLKP N+LL    +   V+++D GLA +    
Sbjct: 365 FTEKEVRFYAAEVMLGLEHMHSRFVVYRDLKPANILL---DENGHVRISDLGLACDFS-- 201

Query: 168 QQAWFGFAGTPGYLSPEVLRK-DPYGKPVDMWACGVILYILLVGYPPFWDEDQ 219
           ++      GT GY++PEVL K   Y    D ++ G +LY LL G+ PF   +Q
Sbjct: 200 KKRPHASVGTHGYMAPEVLMKGQSYDSSADWFSFGCMLYKLLKGHSPFRQHNQ 42
>36002
          Length = 253

 Score = 63.2 bits (152), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 26/55 (47%), Positives = 36/55 (65%)
 Frame = +1

Query: 219 QHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPAKRITASEALKHPWIC 273
           Q  L+ +I+ G Y FPS EW  ++  AKDLI  +L   P KR +A++ LKHPW+C
Sbjct: 49  QELLFNRIQDGNYFFPSMEWSAISSSAKDLIRHLLVREPRKRYSAADVLKHPWVC 213
>12786
          Length = 460

 Score = 63.2 bits (152), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 40/119 (33%), Positives = 58/119 (48%), Gaps = 22/119 (18%)
 Frame = -3

Query: 118 QQILEAVLHCHQMGVVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWF--GFA 175
           +++L AV   H  GV+H DLKP N +L + +    +KL DFG+A  +Q D+ +       
Sbjct: 389 REMLRAVKALHNEGVIHSDLKPANFMLVAGN----LKLIDFGIANTLQQDKTSVLKDSRV 222

Query: 176 GTPGYLSPEVL-----------------RKDP---YGKPVDMWACGVILYILLVGYPPF 214
           GTP Y+SPE +                 R  P    G   D+W+ G ILY ++ G  PF
Sbjct: 221 GTPSYMSPEAIMAACDDSADDSMEEDGHRTKPKYKVGVRSDVWSLGCILYNMVYGRTPF 45
>21418
          Length = 831

 Score = 62.0 bits (149), Expect = 5e-10,   Method: Compositional matrix adjust.
 Identities = 25/57 (43%), Positives = 38/57 (66%)
 Frame = +2

Query: 222 LYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTV 278
           + ++I++G YDFP PEW  V+  AKDLI  ML ++P+KR+   + L++ WI Q   V
Sbjct: 2   MKKRIRSGQYDFPDPEWTNVSQAAKDLIKGMLNVDPSKRLCIEDVLRNKWIAQYDAV 172
>21808
          Length = 1011

 Score = 62.0 bits (149), Expect = 5e-10,   Method: Compositional matrix adjust.
 Identities = 49/195 (25%), Positives = 93/195 (47%), Gaps = 3/195 (1%)
 Frame = +1

Query: 45  INTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVA 104
           I T K    D +    EA+I + L+HP +++L+   +++   +++ +L+  G L E +  
Sbjct: 34  IKTLKSGTMDPKDFLAEAQIMKKLRHPKLIQLYAVCTQDDPIFIITELMKNGSLLEFLQG 213

Query: 105 REYYSEADASHCI-QQILEAVLHCHQMGVVHRDLKPENLLLASKSKGAAVKLADFGLAIE 163
           +    +  A   I  QI   + +      +HRDL   N+L++  +    VK+ADFGLA  
Sbjct: 214 KGRVLKLPALIDIGAQIACGMAYLESQNYIHRDLAARNILVSDNN---TVKIADFGLARV 384

Query: 164 VQGDQ-QAWFGFAGTPGYLSPEVLRKDPYGKPVDMWACGVILY-ILLVGYPPFWDEDQHR 221
           ++ D+ +A  G      + +PE    + +    D+W+ G++L   +  G  P+       
Sbjct: 385 IKEDEYEARVGARFPIKWTAPEAANYNRFTIKSDVWSFGILLTETVTYGRVPYPGMTNAE 564

Query: 222 LYQQIKAGAYDFPSP 236
           +  Q++ G Y  P P
Sbjct: 565 VLHQVEHG-YRMPCP 606
>01756
          Length = 1858

 Score = 61.6 bits (148), Expect = 7e-10,   Method: Compositional matrix adjust.
 Identities = 62/215 (28%), Positives = 94/215 (43%), Gaps = 20/215 (9%)
 Frame = -3

Query: 10   FTDE---YQLFEELGKGAFSVV--RRCMKIPTGQEYAAKIINTKKLSARDHQKLEREARI 64
            F DE   Y+   ++G+G F  V   RC K  T Q  A K +              RE +I
Sbjct: 1757 FCDEDAKYEKLAKIGQGTFGEVFKARCKK--TKQVVAMKKVLMDNEKEGFPITALREIKI 1584

Query: 65   CRLLKHPNIVRLHDSISEEG--------FHYLVFDLV---TGGELFEDIVAREYYSEADA 113
             +LL H N+V L +  S +           YLVF+       G L    V    ++  + 
Sbjct: 1583 LQLLNHENVVDLIEICSTKATSANRYKSMFYLVFEFCEHDLAGLLSNMSVV---FNLPEI 1413

Query: 114  SHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKSKGAAVKLADFGL--AIEVQGDQ-QA 170
               ++Q++  + + H+  ++HRD+K  N+L+   +K   +KLADFGL  A  V   Q   
Sbjct: 1412 KEVMKQLMNGLYYIHRNKILHRDMKAANILI---TKQGVLKLADFGLARAFSVNLRQPNR 1242

Query: 171  WFGFAGTPGYLSPEVLRKD-PYGKPVDMWACGVIL 204
            +     T  Y  PE+L  D  Y   +D W  G I+
Sbjct: 1241 YTNRVVTLWYRPPELLLGDRNYSTAIDQWGAGCIM 1137
>04591
          Length = 1117

 Score = 61.6 bits (148), Expect = 7e-10,   Method: Compositional matrix adjust.
 Identities = 64/252 (25%), Positives = 105/252 (41%), Gaps = 42/252 (16%)
 Frame = -2

Query: 60   REARICRLLKHPNIVRLHDSISEEG-------------FHYLVFDLVTGGELFEDIVARE 106
            RE +I + L+H N+V+L +    +              F Y  +DL     L  ++  R 
Sbjct: 1074 REIKILQQLEHENVVQLQEICHTQAGPYNRYKSTFYLIFEYCDYDLAG---LLNNL--RV 910

Query: 107  YYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQG 166
             +S AD  + + Q+L  + + H   ++HRD+K  N+LL   ++   +KLADFGL+     
Sbjct: 909  KFSLADKKNLMSQLLNGLFYIHTKQILHRDIKAANILL---TRDGVLKLADFGLSRPWVK 739

Query: 167  DQQAWFGFAGTPGYLSPEVLRKD-PYGKPVDMWACGVILYILLVGYPPFWDE-DQHRLY- 223
             ++       T  Y  PE+L  +  YG  +DMW  G I+  +    P      +QH+L  
Sbjct: 738  SKRL-TNRVVTLWYRPPELLLGEREYGPEIDMWGVGCIMAEMWSRKPLMQGRSEQHQLSL 562

Query: 224  -----QQIKA------------GAYDFPSPEWDTV---------TPEAKDLINKMLTINP 257
                   + A            G  D P  +   V           E  +LI+  L ++P
Sbjct: 561  ITDLCGSLNAEVWPGVTKLELYGKLDLPQGKPRKVKERMLDLLKNKEGAELIDIFLRLDP 382

Query: 258  AKRITASEALKH 269
             +R+    AL H
Sbjct: 381  GQRMNCDNALSH 346
>20152
          Length = 445

 Score = 61.6 bits (148), Expect = 8e-10,   Method: Compositional matrix adjust.
 Identities = 34/91 (37%), Positives = 47/91 (51%), Gaps = 1/91 (1%)
 Frame = +1

Query: 183 PEVLRKDPYGKP-VDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTV 241
           PE+L  D Y  P VD+W+ GVILY+L+VG  PF + +       I    Y  P      +
Sbjct: 1   PEILLGDSYDAPAVDVWSLGVILYMLVVGEAPFQEANDSETLTMIMDCRYQIPP----HI 168

Query: 242 TPEAKDLINKMLTINPAKRITASEALKHPWI 272
           + + +DLI KML   P  R +    L HPW+
Sbjct: 169 SHKCQDLIEKMLQREPVDRASLPHILAHPWL 261
>29590
          Length = 320

 Score = 46.6 bits (109), Expect(2) = 1e-09,   Method: Composition-based stats.
 Identities = 18/39 (46%), Positives = 25/39 (64%)
 Frame = +3

Query: 176 GTPGYLSPEVLRKDPYGKPVDMWACGVILYILLVGYPPF 214
           GTP Y++PEVL  +P     DMW+ GV+ Y++L    PF
Sbjct: 60  GTPDYVAPEVLDYEPLSIQTDMWSLGVLSYVMLTACSPF 176

 Score = 34.3 bits (77), Expect(2) = 1e-09,   Method: Composition-based stats.
 Identities = 15/46 (32%), Positives = 24/46 (52%)
 Frame = +2

Query: 217 EDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPAKRIT 262
           ++Q   +  I     DFP   +  ++P AKD I K+L  +P  R+T
Sbjct: 182 DNQQETFCNISQVKLDFPDDLFSHISPHAKDFIKKLLVKDPRHRMT 319
>18663
          Length = 600

 Score = 57.0 bits (136), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 35/97 (36%), Positives = 51/97 (52%), Gaps = 9/97 (9%)
 Frame = +2

Query: 174 FAGTPGYLSPEVLRKDPYGKPVDMWACGVILYILLVGYPPF------WDEDQHR---LYQ 224
           F GTP Y++PE+LR + YG  VD WA GV+LY +L G  PF       + DQ+    L+Q
Sbjct: 8   FCGTPNYIAPEILRGEDYGFSVDWWALGVLLYEMLAGRSPFDIAGASENPDQNTEDYLFQ 187

Query: 225 QIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPAKRI 261
            I       P     +++ +A  ++   L  NPA R+
Sbjct: 188 VILEKTIRIPR----SLSVKAASVLKGFLNKNPADRL 286
>04138
          Length = 800

 Score = 55.5 bits (132), Expect = 5e-08,   Method: Compositional matrix adjust.
 Identities = 54/182 (29%), Positives = 78/182 (42%), Gaps = 34/182 (18%)
 Frame = +1

Query: 122 EAVLHCHQMGVVHRDLKPENLLLASKSKGAAVKLADFGL--AIEVQGDQ-QAWFGFAGTP 178
           E + + H+  ++HRD+K  N+L+   +K   +KLADFGL  A  V   Q   +     T 
Sbjct: 46  ERLYYIHRNKILHRDMKAANILI---TKQGVLKLADFGLARAFSVNLRQPNRYTNRVVTL 216

Query: 179 GYLSPEVLRKD-PYGKPVDMWACGVI---------------------LYILLVG--YPPF 214
            Y  PE+L  D  Y   +D W  G I                     L   L G   P  
Sbjct: 217 WYRPPELLLGDRNYSTAIDQWGAGCIMAEMWTRNPIMQGTTEQNQLTLITQLCGSITPEV 396

Query: 215 W-DEDQHRLYQQIK----AGAYDFPSPEWDTVT--PEAKDLINKMLTINPAKRITASEAL 267
           W    Q  +Y QIK    AG  +     +  +   P   DL  ++L ++P++RI+A EAL
Sbjct: 397 WPGVTQLSMYHQIKGALAAGRKNIIRDRFARILKDPYGLDLFERLLKMDPSQRISADEAL 576

Query: 268 KH 269
            H
Sbjct: 577 NH 582
>31120
          Length = 439

 Score = 55.1 bits (131), Expect = 7e-08,   Method: Composition-based stats.
 Identities = 31/90 (34%), Positives = 48/90 (53%), Gaps = 1/90 (1%)
 Frame = +1

Query: 184 EVLRKDPYG-KPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVT 242
           EV+   PY  K  D W+ GVIL+I+L G  PF D + ++L +  ++  Y F     D V+
Sbjct: 1   EVVCGVPYDPKMADAWSLGVILFIMLNGKMPFDDSNLNKLLEDQRSKKYSFRRKLQDLVS 180

Query: 243 PEAKDLINKMLTINPAKRITASEALKHPWI 272
           P A+  ++ +L  N A R   +E L   W+
Sbjct: 181 PNARSTVSVLLEPNSAMRWDLNEVLNCQWL 270
>27274
          Length = 396

 Score = 54.7 bits (130), Expect = 9e-08,   Method: Composition-based stats.
 Identities = 30/99 (30%), Positives = 51/99 (51%), Gaps = 8/99 (8%)
 Frame = -1

Query: 184 EVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHR--------LYQQIKAGAYDFPS 235
           E+LR   +G  VDMW+ G++L+ LL G+ PF  E   R        +Y QI  G+     
Sbjct: 375 ELLRGQQHGPTVDMWSLGILLHELLSGHVPFEPERGSRQMARNMMAVYAQIIRGS-SRDV 199

Query: 236 PEWDTVTPEAKDLINKMLTINPAKRITASEALKHPWICQ 274
            +   ++    D + +++ +   KR+T+ +A  HPWI +
Sbjct: 198 CDGLALSTHGADFLRRLVQLEDTKRLTSQQAFSHPWIAR 82
>20655
          Length = 1181

 Score = 53.9 bits (128), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 21/57 (36%), Positives = 34/57 (59%)
 Frame = +2

Query: 222 LYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTV 278
           + ++I+ G Y+FP PEW  V+ +AKDLI  ML  +P KR+   + +   W+   + V
Sbjct: 2   MKKRIRNGQYEFPKPEWSRVSQDAKDLIRGMLCTDPDKRLNIKQVMASKWVADNTMV 172
>27546
          Length = 426

 Score = 53.9 bits (128), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 38/103 (36%), Positives = 52/103 (50%), Gaps = 1/103 (0%)
 Frame = -1

Query: 60  REARICRLLKHPNIVRLHDSISEEGFHYLVF-DLVTGGELFEDIVAREYYSEADASHCIQ 118
           RE  I   L HPNI+++H SI + G    +F      G++   I       EA       
Sbjct: 333 RELEILTRLDHPNIIQIH-SILQRGPKIFIFMRYAEKGDMLSHIKKTGPIDEAQTKVWFF 157

Query: 119 QILEAVLHCHQMGVVHRDLKPENLLLASKSKGAAVKLADFGLA 161
           Q+ +A+ + H   + HRDLK EN+LL   SK   VK+ADFG A
Sbjct: 156 QMAKALQYLHSHDIAHRDLKCENILL---SKRLNVKIADFGFA 37
>03508
          Length = 1463

 Score = 53.1 bits (126), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 44/198 (22%), Positives = 91/198 (45%), Gaps = 5/198 (2%)
 Frame = +1

Query: 12  DEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLEREARICRLLKHP 71
           D+YQ+  +LG+G +S V   + +   +    K +       +  +       +  L    
Sbjct: 589 DDYQIVRKLGRGKYSEVFEAINVTNNE----KCVIKILKPVKKKKIKREIKILENLRGGT 756

Query: 72  NIVRL----HDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHC 127
           N++ L     D +S      L+F+ V   +  +     + +++ D    + ++++A+  C
Sbjct: 757 NVITLLAIVKDPVSRTPA--LIFEHVNNTDFKQ---LYQTFTDYDIRFYLYELMKALDFC 921

Query: 128 HQMGVVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLR 187
           H MG++HRD+KP N+++  ++K   ++L D+GLA E       +     +  +  PE+L 
Sbjct: 922 HSMGIMHRDVKPHNVMIDHENK--KLRLIDWGLA-EFYHPGMEYNVRVASRYFKGPELLL 1092

Query: 188 K-DPYGKPVDMWACGVIL 204
               Y   +DMW+ G + 
Sbjct: 1093DYQMYDYSLDMWSLGCMF 1146

 Score = 36.2 bits (82), Expect = 0.030,   Method: Compositional matrix adjust.
 Identities = 13/32 (40%), Positives = 23/32 (71%)
 Frame = +2

Query: 241  VTPEAKDLINKMLTINPAKRITASEALKHPWI 272
            ++PEA D ++K+L  +  +R+TA EA+ HP+ 
Sbjct: 1358 ISPEALDFLDKLLRYDHNERLTAREAMDHPYF 1453
>04852
          Length = 1462

 Score = 52.8 bits (125), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 54/236 (22%), Positives = 98/236 (41%), Gaps = 31/236 (13%)
 Frame = +1

Query: 33  KIPTGQEYAAKIINTKKLSARDHQKLEREARICRLLK----HPNIVRLHDSISEEGFHYL 88
           ++P     A K++    ++A + Q   +E ++ + +K    H NIV      ++ G  ++
Sbjct: 7   RVPKASTVAVKMLR-DIVTAVEEQDFVQELQVMKAVKKMGSHINIVNFLGCCTQGGPLWV 183

Query: 89  VFDLVTGGEL-------------FEDIVARE---YYSEADASHCIQ---------QILEA 123
           + +    G L             +   V+ +   +Y++    H I+         QI   
Sbjct: 184 IVEFAKNGNLRDFLESCRDGINGYGKFVSPQDPGWYTKTPGGHVIRRKNLLSYAFQIARG 363

Query: 124 VLHCHQMGVVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTP-GYLS 182
           +        +HRDL   N+L+  +     +K+ADFGL+    GD          P  +++
Sbjct: 364 MEFLASRKCIHRDLAARNVLVTEEH---VLKIADFGLS--RTGDYYKKRSGGRLPVKWMA 528

Query: 183 PEVLRKDPYGKPVDMWACGVILY-ILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPE 237
           PE L    Y    D+W+ GV+L+ I  +G  P+       LY ++   AY  P PE
Sbjct: 529 PEALFDMRYTTKSDVWSFGVVLWEIFSLGGMPYASIPNEELYSKLLDDAYRMPRPE 696
>11185
          Length = 473

 Score = 51.6 bits (122), Expect = 8e-07,   Method: Composition-based stats.
 Identities = 40/175 (22%), Positives = 76/175 (43%), Gaps = 22/175 (12%)
 Frame = +1

Query: 119 QILEAVLHCHQMGVVHRDLKPENLLLASKSKGAAVKLADFGLA-IEVQGDQQAWFGFA-- 175
            ++  + + H +G++  DL+P  +LL +      +K ADFGL+ +E +  ++ +F FA  
Sbjct: 25  HLVTGLHYIHSLGILFHDLRPSKVLLDTS---GVLKFADFGLSKVEGENLEELFFKFAEA 195

Query: 176 -------------------GTPGYLSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWD 216
                              G+P Y++PEV +        D+WA G + Y +  G      
Sbjct: 196 GDQWNIQSAEEMMKQVPTSGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFSG------ 357

Query: 217 EDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPAKRITASEALKHPW 271
               RL  +        PSPE+        +L+  +L  +  +R++ +  +KH +
Sbjct: 358 ---SRLSAK--------PSPEF-------LNLLESLLQKDSTRRLSWASLVKHAF 468
>28157
          Length = 400

 Score = 51.6 bits (122), Expect = 8e-07,   Method: Compositional matrix adjust.
 Identities = 39/134 (29%), Positives = 67/134 (50%), Gaps = 6/134 (4%)
 Frame = +3

Query: 38  QEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGE 97
           ++ A K I +++      Q+L++ +R+     HPNIV L+ +  +     LV +   GG 
Sbjct: 3   KDVAVKRIESEQEKKSFMQELKQLSRV----SHPNIVCLYGACRDHPV-CLVMEYAEGGS 167

Query: 98  LFEDIVAREYYSEADASHCIQQILEAVL---HCHQM---GVVHRDLKPENLLLASKSKGA 151
           L+  +       +  A+H +  +L+  L   + H M    ++HRDLKP NLLL     G 
Sbjct: 168 LYNVLHGSGPQPQYTAAHAMNWLLQCALGVEYLHGMKPKALIHRDLKPPNLLLI--QCGT 341

Query: 152 AVKLADFGLAIEVQ 165
            +K+ DFG A ++ 
Sbjct: 342 KLKICDFGTACDIH 383
>02638
          Length = 1490

 Score = 51.2 bits (121), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 28/96 (29%), Positives = 50/96 (52%), Gaps = 1/96 (1%)
 Frame = +1

Query: 176 GTPGYLSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDED-QHRLYQQIKAGAYDFP 234
           GT  +++PEVLR + YG+  D+W+ G ++  +    PP+   D  + L    K  +   P
Sbjct: 22  GTIAFMAPEVLRGESYGRACDVWSVGCVMIEMCTCRPPWNSHDISNHLALIFKIASSVDP 201

Query: 235 SPEWDTVTPEAKDLINKMLTINPAKRITASEALKHP 270
            P  + ++P  +DL+ + L  +   R +A + L HP
Sbjct: 202 PPIPENMSPPVRDLMLRCLEQDSDFRPSAKDLLMHP 309
>17300
          Length = 480

 Score = 50.8 bits (120), Expect = 1e-06,   Method: Composition-based stats.
 Identities = 32/112 (28%), Positives = 57/112 (50%), Gaps = 7/112 (6%)
 Frame = +1

Query: 130 MGVVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPG------YLSP 183
           MG VHRDL   N+L+   ++    K+ADFGL+ E++ D     G   T G      + +P
Sbjct: 31  MGYVHRDLAARNILV---NEILVCKVADFGLSREIESDTTE--GAYTTKGGKIPVRWTAP 195

Query: 184 EVLRKDPYGKPVDMWACGVILY-ILLVGYPPFWDEDQHRLYQQIKAGAYDFP 234
           E +    +    D+W+ GV+++ ++  G  P+W+     + + ++ G Y  P
Sbjct: 196 EAIAYRKFTSASDVWSFGVVMWEVMSYGERPYWNWSNQDVIKAVEKG-YRLP 348
>32000
          Length = 644

 Score = 50.4 bits (119), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 44/147 (29%), Positives = 69/147 (46%), Gaps = 25/147 (17%)
 Frame = -1

Query: 151 AAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRK-DPYGKPVDMWACGVILYILLV 209
           A +K+ADFGLA       + +     T  Y +PE+L     Y  PVD+W+ G I   ++ 
Sbjct: 578 AKMKIADFGLARVFGLPVRTYTHEVITLWYRAPEILLGCRFYSVPVDIWSLGCIFVEMMT 399

Query: 210 GYPPF-WDEDQHRLY----------QQIKAGAYDFPS-----PEW-----DTVTPEAK-- 246
               F  D +  +LY          +++  G    P      P+W     +TV   +K  
Sbjct: 398 RRALFPGDSEIDQLYRIFRTLGTPDEKVWPGVSKLPDYKPTFPKWPLKNLETVVSLSKVG 219

Query: 247 -DLINKMLTINPAKRITASEALKHPWI 272
            DL+ +MLT NP +RI+A  A++HP+ 
Sbjct: 218 LDLLKRMLTYNPNRRISARSAMRHPYF 138
>17722
          Length = 680

 Score = 50.1 bits (118), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 25/72 (34%), Positives = 40/72 (55%)
 Frame = -3

Query: 195 VDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLT 254
           VD W  GV++Y ++ G  PF++ D   L++ I      FP      ++ EAK L++ +L 
Sbjct: 678 VDWWGTGVVMYEMMCGRLPFYNRDHDVLFELILLQNVKFPR----NLSEEAKTLLSGLLA 511

Query: 255 INPAKRITASEA 266
            NP +R+  SEA
Sbjct: 510 KNPKRRLGGSEA 475
>19094
          Length = 898

 Score = 50.1 bits (118), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 27/93 (29%), Positives = 50/93 (53%)
 Frame = +1

Query: 110 EADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQ 169
           E + +  +   L+ + + H    +HRD+K  N+LL ++      KLADFG+A ++     
Sbjct: 55  EREIATILYYTLKGL*YLHSRRKIHRDIKAGNILLNNEGH---AKLADFGVAGQLTDTMA 225

Query: 170 AWFGFAGTPGYLSPEVLRKDPYGKPVDMWACGV 202
                 GTP +++PEV+++  Y    D+W+ G+
Sbjct: 226 KRNTVIGTPYWMAPEVIQEIGYDCVADIWSLGI 324
>11780
          Length = 1713

 Score = 50.1 bits (118), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 45/151 (29%), Positives = 71/151 (47%), Gaps = 2/151 (1%)
 Frame = +3

Query: 13  EYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPN 72
           + ++ E +GKG F  V + M    GQ  A K +  K    R  Q   +EA +   L+H N
Sbjct: 600 DLEIGEAIGKGDFGDVYKGMY--RGQPVAIKQLKDKD---RGEQSFLQEASVMTSLRHDN 764

Query: 73  IVRLHDSISEEGFHYLVFDLVTGGELFEDIVA--REYYSEADASHCIQQILEAVLHCHQM 130
           +VRL   +  E   +LV + +  G L E + +  R   ++ D  +       A+ +    
Sbjct: 765 LVRLIGVVLGETI-FLVTEFMGKGNLVEYLRSRGRSVITKKDQINFATDTCAAMEYLESK 941

Query: 131 GVVHRDLKPENLLLASKSKGAAVKLADFGLA 161
            +VHRDL   N+L+    K    K++DFGLA
Sbjct: 942 RLVHRDLAARNVLVHDDGK---AKVSDFGLA 1025
>19301
          Length = 712

 Score = 48.5 bits (114), Expect = 6e-06,   Method: Compositional matrix adjust.
 Identities = 29/101 (28%), Positives = 50/101 (49%)
 Frame = +2

Query: 59  EREARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQ 118
           E + R  R L HPNI+      ++   + ++ +    G+L+E +   +    A      +
Sbjct: 413 ETDIRNLRKLNHPNIISFKGVCTQAPCYCIIMEYCPYGQLYEVLRDGKEIPPALVLDWSK 592

Query: 119 QILEAVLHCHQMGVVHRDLKPENLLLASKSKGAAVKLADFG 159
           QI   + + H   ++HRDLK  N+L+A   K   VK++DFG
Sbjct: 593 QIASGMNYLHSHKIIHRDLKSPNVLVA---KNDVVKISDFG 706
>18481
          Length = 437

 Score = 48.1 bits (113), Expect = 7e-06,   Method: Composition-based stats.
 Identities = 38/137 (27%), Positives = 67/137 (48%), Gaps = 5/137 (3%)
 Frame = -1

Query: 37  GQEYAAKI--INTKKLSARDHQKLEREARICRLL-KHPNIVRLHDSISEEGFHYLVFDLV 93
           G++ A KI  I+ K      HQ L  EA++   + +HP +  ++   +E+ F+ LV +L+
Sbjct: 410 GKDIAVKIEAIDVK------HQLLHYEAKVYEQIGRHPGLPTMYHYGTEKHFNALVMELL 249

Query: 94  TGG--ELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKSKGA 151
                ELF  ++ +  ++         Q+L  +   HQ   +HRDLKP+N L+       
Sbjct: 248 GPSLEELF--VICKRRFTLKTILMVSDQLLSRLEFIHQKCFIHRDLKPDNFLMGLGRHCH 75

Query: 152 AVKLADFGLAIEVQGDQ 168
            + + DFGL+   +  Q
Sbjct: 74  RLYIIDFGLSKRYKDTQ 24
>00715
          Length = 1788

 Score = 46.6 bits (109), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 48/198 (24%), Positives = 82/198 (41%), Gaps = 29/198 (14%)
 Frame = +1

Query: 68  LKHPNIVRLHDSISEEGFH---YLVFDLVTGGELFEDIVAREYYSEADASHCIQ---QIL 121
           L+H N+V +  + S   F    +L  + V  G L    +  ++  + D+S  +    Q+ 
Sbjct: 97  LRHVNVVSILGATSLHRFEDGAWLAMEYV--GPLNLQTILNDHQQDIDSSMRLSLALQMA 270

Query: 122 EAVLHCHQMGVVHRDLKPENLLLASKSKGAAVKLADFGLA-------------------- 161
             + + H + +VH DLKP N LL    K   +++ADFG                      
Sbjct: 271 RGLHYLHSINIVHLDLKPANCLLTRDLK---LRIADFGCCHQLTPTGLDMGEREGGMAGN 441

Query: 162 -IEVQGDQQAWFG-FAGTPGYLSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQ 219
            +E+   Q AW    AGT  Y +PE+L+        D+++ G+ L+ +     P+     
Sbjct: 442 ELELTPVQGAWKNELAGTLAYRAPELLKGLQPSVRSDVYSLGITLWQMCTRQGPYEGVPA 621

Query: 220 HR-LYQQIKAGAYDFPSP 236
           H  +YQ +       P P
Sbjct: 622 HAVVYQVVSKDLRPCPPP 675
>14116
          Length = 1017

 Score = 46.2 bits (108), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 50/202 (24%), Positives = 88/202 (43%), Gaps = 11/202 (5%)
 Frame = -1

Query: 18  EELGKGAFSVVRRCMKIPTGQE----YAAKIINTKKLSARDHQKLEREARICRLLKHPNI 73
           EE+GKG F  V+R       Q+     A K ++       + Q   +EA I +   H N+
Sbjct: 618 EEIGKGNFGCVKRGFLTLPEQKGDILVAVKTLHNNNPREIELQSFLQEALIMKDFHHSNV 439

Query: 74  VRLHD-SISEEGFHYLVFDLVTGGELFEDIVAREYY-SEADASHCIQQILEAVLHCHQMG 131
           + L    ++ +    +V   +  G+L   I   ++  +  D       I   + +   + 
Sbjct: 438 LTLIGICLNLDDMPLVVLPFMKHGDLLTYIRDDQHQPTIKDLIMYGVDIARGMDYLAGLK 259

Query: 132 VVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPG-----YLSPEVL 186
            VHRDL   N +L    +   VK+ADFGLA ++   ++ ++            +++ E L
Sbjct: 258 FVHRDLAARNCML---DEDFHVKVADFGLARDIY--EKEYYSSENKKAKLPVKWMALESL 94

Query: 187 RKDPYGKPVDMWACGVILYILL 208
            K  Y    D+W+ GV+L+ LL
Sbjct: 93  EKGNYDSKTDVWSYGVVLWELL 28
>31489
          Length = 329

 Score = 45.8 bits (107), Expect = 4e-05,   Method: Composition-based stats.
 Identities = 28/87 (32%), Positives = 48/87 (55%), Gaps = 6/87 (6%)
 Frame = +3

Query: 63  RICRLLKHPNIVRLHDSIS-EEGFH-----YLVFDLVTGGELFEDIVAREYYSEADASHC 116
           +I +  KH NI+ + + +  ++ +H     ++VFDL+   +L   I + +  +E    + 
Sbjct: 6   KILKHFKHDNIISIREILKPKDSYHDFKDIHVVFDLMES-DLHRIIYSDQPLTEEHIRYF 182

Query: 117 IQQILEAVLHCHQMGVVHRDLKPENLL 143
           + QIL  + + H   VVHRDLKP NLL
Sbjct: 183 LYQILRGLKYIHSANVVHRDLKPSNLL 263
>25019
          Length = 730

 Score = 45.8 bits (107), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 26/62 (41%), Positives = 34/62 (54%)
 Frame = +3

Query: 140 ENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKDPYGKPVDMWA 199
           EN+LL    K   VKL DFGL  E     +    F GT  Y++PE+L +  +GK VD W+
Sbjct: 261 ENVLL---DKDGHVKLTDFGLCKEAITGTRVTHTFCGTIEYMAPEILTRTGHGKAVDWWS 431

Query: 200 CG 201
            G
Sbjct: 432 LG 437
>07291
          Length = 833

 Score = 45.1 bits (105), Expect = 8e-05,   Method: Compositional matrix adjust.
 Identities = 29/118 (24%), Positives = 60/118 (50%), Gaps = 6/118 (5%)
 Frame = +1

Query: 118 QQILEAVLHCHQMGVVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGT 177
           +QI + + +  ++ VVHR+L   N ++    +   ++L+D+G+   +    Q+++    +
Sbjct: 70  RQIADGMAYLQEVKVVHRNLAARNCIVTEDGR---LQLSDYGVTGSLF--PQSYYTADDS 234

Query: 178 PG-----YLSPEVLRKDPYGKPVDMWACGVILYILLV-GYPPFWDEDQHRLYQQIKAG 229
           P      +++PE +    +    D+WA GV+L+ LL  G  P+ D +   L   +K G
Sbjct: 235 PARDLVKWMAPETIDNFHFSSKSDVWAFGVVLWELLTRGITPYPDVENSSLLPYLKEG 408
>00394
          Length = 548

 Score = 44.7 bits (104), Expect = 9e-05,   Method: Compositional matrix adjust.
 Identities = 27/85 (31%), Positives = 42/85 (49%), Gaps = 5/85 (5%)
 Frame = -2

Query: 19  ELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHD 78
           E+G+G+F  V + +    G   A   +  KK +  + Q+ + EA + + L+HPNIVR  D
Sbjct: 277 EIGRGSFKTVYKGLDTELGVAVAWCELQDKKWNKAERQRFKEEAEMLKELQHPNIVRFFD 98

Query: 79  SISEEGFH-----YLVFDLVTGGEL 98
              E          LV +L+T G L
Sbjct: 97  YWEEHNHRNRKVIILVTELMTSGTL 23
>31789
          Length = 676

 Score = 44.7 bits (104), Expect = 9e-05,   Method: Compositional matrix adjust.
 Identities = 27/85 (31%), Positives = 42/85 (49%), Gaps = 5/85 (5%)
 Frame = +2

Query: 19  ELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHD 78
           E+G+G+F  V + +    G   A   +  KK +  + Q+ + EA + + L+HPNIVR  D
Sbjct: 341 EIGRGSFKTVYKGLDTELGVAVAWCELQDKKWNKTERQRFKEEAEMLKELQHPNIVRFFD 520

Query: 79  SISEEGFH-----YLVFDLVTGGEL 98
              E          LV +L+T G L
Sbjct: 521 YWEEHNHRNRKVIILVTELMTSGTL 595
>32957
          Length = 645

 Score = 42.7 bits (99), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 21/51 (41%), Positives = 29/51 (56%)
 Frame = +3

Query: 158 FGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKDPYGKPVDMWACGVILYILL 208
           F L +E  G +     F GT  Y++PEV  +  YGK VD W  G++L+ LL
Sbjct: 3   FALCVEKSGGRTR--TFCGTREYMAPEVHERKEYGKEVDWWGLGILLHELL 149
>11404
          Length = 563

 Score = 42.4 bits (98), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 40/155 (25%), Positives = 69/155 (44%), Gaps = 17/155 (10%)
 Frame = +1

Query: 9   RFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKK------------LSARDHQ 56
           ++ D Y++   +GKG+F  V +       ++ A KII  KK            L   +  
Sbjct: 130 KWADRYEIDSLIGKGSFGQVVKAYDHTDNEQVAIKIIKNKKPFLNQAQIEVKLLEMMNRH 309

Query: 57  KLEREARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDI---VAREYYSEADA 113
             + +  I RL +H  + R H  +  E   Y ++DL+     F  +   + R++      
Sbjct: 310 DTDNKYYIVRLKRHF-MFRSHLCLVFELLSYNLYDLLRNTN-FRGVSLNLTRKF------ 465

Query: 114 SHCIQQILEAVLHCH--QMGVVHRDLKPENLLLAS 146
               QQ+  A+L     +M ++H DLKPEN+LL +
Sbjct: 466 ---AQQLCTALLFLATPEMSIIHCDLKPENILLCN 561
>36481
          Length = 806

 Score = 41.2 bits (95), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 42/145 (28%), Positives = 63/145 (43%), Gaps = 7/145 (4%)
 Frame = +2

Query: 8   TRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKII-NTKKLSARDHQKLEREARICR 66
           T  T++ +L    G+G F  V +C  +  G + A KII N  K   R+  KLE       
Sbjct: 350 TSSTNDMKLCPHWGEGTFGKVVQCKDLLKGDDIALKIIKNVDKY--REAAKLEINVLEKL 523

Query: 67  LLKHPN----IVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREY--YSEADASHCIQQI 120
             K P+     V++ D     G   + F ++ G  +F+ +    Y  Y      H   Q+
Sbjct: 524 REKDPHAKHMCVQMLDWFDYHGHVCISFHML-GLSVFDFLKDNSYGAYPIEQVRHISYQL 700

Query: 121 LEAVLHCHQMGVVHRDLKPENLLLA 145
             AV   H+  + H DLKPEN+L  
Sbjct: 701 CYAVNFLHENQLTHTDLKPENILFV 775
>01106
          Length = 878

 Score = 41.2 bits (95), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 39/148 (26%), Positives = 67/148 (45%), Gaps = 12/148 (8%)
 Frame = +3

Query: 10  FTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKL---SARDHQKLEREARICR 66
           F   Y +  +LG G FS V  C  +   +  A K++ + +    +A D  KL +  R   
Sbjct: 312 FNGRYHVIRKLGWGHFSTVWLCWDLTCKRFVALKVVKSAQHYTETALDEVKLLKCVRESD 491

Query: 67  LLK--HPNIVRLHDSISEEGFH----YLVFDLVTGGELFEDIVAREYYSEA--DASHCIQ 118
           +        V+L D     G +     +VF+ V G  L + I+   Y      +    I+
Sbjct: 492 VADPARAKCVQLLDDFKISGVNGTHVAMVFE-VLGYNLLKLIIRSNYQGIPIHNVKLIIR 668

Query: 119 QILEAVLHCH-QMGVVHRDLKPENLLLA 145
           Q+LE + + H +  ++H D+KPEN+L+ 
Sbjct: 669 QVLEGLSYMHAKCRIIHTDIKPENILIC 752
>37063
          Length = 455

 Score = 40.8 bits (94), Expect = 0.001,   Method: Composition-based stats.
 Identities = 28/83 (33%), Positives = 41/83 (49%), Gaps = 10/83 (12%)
 Frame = -2

Query: 137 LKPENLLLASKSKGAAVKLADFGLA--IEVQGD---QQAWFGFAGTPGYLSPEVL----- 186
           LKPEN+L     +   +K+ DF LA  I   GD           G+  Y++PEV+     
Sbjct: 454 LKPENILCEHLDEVVPLKICDFDLASGINCDGDGTKTPELLTPVGSAEYMAPEVVDAWVG 275

Query: 187 RKDPYGKPVDMWACGVILYILLV 209
               Y K  DMW+ G+IL +L++
Sbjct: 274 ESFSYDKRCDMWSLGIIL*VLVM 206
>07940
          Length = 1336

 Score = 40.8 bits (94), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 29/88 (32%), Positives = 46/88 (52%), Gaps = 6/88 (6%)
 Frame = -3

Query: 133 VHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPG-----YLSPEVLR 187
           +HRDL   N+L+A +     +K+ADFGL   +Q   Q  +    T G     +++PE L 
Sbjct: 281 IHRDLAARNVLVAEEY---VLKIADFGLTRNLQ---QFDYYRKTTDGRLPVKWMAPEALF 120

Query: 188 KDPYGKPVDMWACGVILY-ILLVGYPPF 214
              Y    D+W+ GV+L+ I  +G  P+
Sbjct: 119 DRKYTSKSDVWSYGVLLWEIFTLGGNPY 36
>12672
          Length = 773

 Score = 39.3 bits (90), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 27/92 (29%), Positives = 44/92 (47%), Gaps = 4/92 (4%)
 Frame = +3

Query: 123 AVLHCHQMGVVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQ----QAWFGFAGTP 178
            + + +  G VHRD+K  N+LL S+      K+ DF   +     +    Q      GT 
Sbjct: 27  GIQYLNDNGHVHRDIKTANILLDSEYTA---KVGDFATVVSAPSGEGKTVQNASVVIGTA 197

Query: 179 GYLSPEVLRKDPYGKPVDMWACGVILYILLVG 210
            YL+PE +  D   K +D ++ GV+L  ++ G
Sbjct: 198 AYLAPEAIHFDVSTK-LDSYSFGVVLLEVITG 290
>23319
          Length = 2235

 Score = 39.3 bits (90), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 31/116 (26%), Positives = 50/116 (43%), Gaps = 26/116 (22%)
 Frame = +3

Query: 183 PEVLRKDPYGKPVDMWACGVILYILLVGYPPFW----DEDQ-HRLYQQIKAGAYD----- 232
           P+V     Y   +DMW+ G I   L     P +    D+DQ  R+++ +     D     
Sbjct: 3   PDVYXAKMYSTSIDMWSAGCIFAELANAGRPLFPGNDDDDQLKRIFKLLGTPTEDQWPGM 182

Query: 233 --------FP----SPEWDTVTPE----AKDLINKMLTINPAKRITASEALKHPWI 272
                   FP    +  W  V P+     +DL+  +L   P+ R++A EAL+HP+ 
Sbjct: 183 TQLPNYRMFPMYHVTTTWQQVVPKLNSKGRDLLQCLLVCCPSDRMSADEALQHPYF 350
>20773
          Length = 391

 Score = 38.9 bits (89), Expect = 0.005,   Method: Composition-based stats.
 Identities = 15/39 (38%), Positives = 25/39 (64%)
 Frame = -1

Query: 236 PEWDTVTPEAKDLINKMLTINPAKRITASEALKHPWICQ 274
           P    VT    +L+ ++LT +P++R+T   AL HP++CQ
Sbjct: 337 PHTTVVTQHFYNLVQRLLTYDPSQRLTPDLALSHPFVCQ 221
>18287
          Length = 678

 Score = 37.7 bits (86), Expect = 0.010,   Method: Compositional matrix adjust.
 Identities = 16/31 (51%), Positives = 22/31 (70%)
 Frame = -3

Query: 242 TPEAKDLINKMLTINPAKRITASEALKHPWI 272
           T EA  L+ +ML +NP  RI+A EAL HP++
Sbjct: 436 THEAVRLLTRMLILNPKNRISAEEALSHPYL 344
>08294
          Length = 1849

 Score = 37.7 bits (86), Expect = 0.011,   Method: Compositional matrix adjust.
 Identities = 56/227 (24%), Positives = 91/227 (40%), Gaps = 17/227 (7%)
 Frame = +2

Query: 71   PNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVARE------------YYSEADASHCIQ 118
            PNIV       E   H+L+ +    G+L + ++A                + +      Q
Sbjct: 887  PNIVHFMGVCREAEPHFLITEYCDWGDLKQFLLATRNDNGRGRGTRVPALALSQKLGMGQ 1066

Query: 119  QILEAVLHCHQMGVVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTP 178
            Q+   +      G+VH DL   N+LL S+ +   +K+A   L+ +V   +         P
Sbjct: 1067 QVAAGMEALSNQGLVHGDLAARNVLLTSRMQ---LKVARPALSGDVYASEYYPLHQRLVP 1237

Query: 179  -GYLSPEVLRKDPYGKPVDMWACGVILYILL----VGYPPFWDEDQHRLYQQIKAGAYDF 233
              +L PE + +D      D+WA GV L+ +L    + Y    DE+  R  Q  +A A D 
Sbjct: 1238 LRWLPPEGVLEDSATTCGDVWAFGVFLWEVLQLADLPYRLMSDEEVLRSLQHSQA-ALDS 1414

Query: 234  PSPEWDTVTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVAS 280
            P        P    L+ +     P++R   SE      IC   ++AS
Sbjct: 1415 PD-----APPALLSLLQRCTAQQPSQRPPFSE------ICSVLSLAS 1522
>18996
          Length = 491

 Score = 37.4 bits (85), Expect = 0.013,   Method: Compositional matrix adjust.
 Identities = 23/79 (29%), Positives = 39/79 (49%), Gaps = 3/79 (3%)
 Frame = +2

Query: 133 VHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTP---GYLSPEVLRKD 189
           +HRDL   N+L+      + VK++DFGLA     D   ++G +       + SPE +   
Sbjct: 2   IHRDLAARNILVDR----SCVKISDFGLAQFANADG-YYYGISQRDIPIKWYSPEAIETC 166

Query: 190 PYGKPVDMWACGVILYILL 208
            +    D+W+ GV L+ + 
Sbjct: 167 KFSSYSDVWSYGVTLFEMF 223
>17644
          Length = 463

 Score = 37.4 bits (85), Expect = 0.014,   Method: Composition-based stats.
 Identities = 15/39 (38%), Positives = 24/39 (61%)
 Frame = +3

Query: 236 PEWDTVTPEAKDLINKMLTINPAKRITASEALKHPWICQ 274
           P    VT    BL+ ++LT +P++R+T   AL HP++CQ
Sbjct: 54  PHTTVVTQHFYBLVQRLLTYDPSQRLTPDLALSHPFVCQ 170
>29360
          Length = 363

 Score = 37.0 bits (84), Expect = 0.017,   Method: Compositional matrix adjust.
 Identities = 33/124 (26%), Positives = 53/124 (42%), Gaps = 8/124 (6%)
 Frame = +3

Query: 30  RCMKIPTGQEYAAKIINTKKLSARDHQKLEREARICRLLKHP-----NIVRLHDSISEEG 84
           +C K  T +  A KI+      AR  Q    E  I + L        N VR  +    + 
Sbjct: 6   KCWKKGTSEIVAIKILKNHPSYARQGQI---EVSILQRLSQESADDYNFVRAFECFQHKN 176

Query: 85  FHYLVFDLVTGGELFEDIVAREYYSEADASHC---IQQILEAVLHCHQMGVVHRDLKPEN 141
              LVF+++       D + +  +      +     QQ+L A+    Q+G++H DLKPEN
Sbjct: 177 HTCLVFEMLEQN--LYDFLKQNKFQPLPLKYIRPITQQVLTALRKLKQLGLIHADLKPEN 350

Query: 142 LLLA 145
           ++L 
Sbjct: 351 IMLV 362
>15549
          Length = 470

 Score = 36.6 bits (83), Expect = 0.022,   Method: Compositional matrix adjust.
 Identities = 16/38 (42%), Positives = 23/38 (60%)
 Frame = -1

Query: 8   TRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKII 45
           +RF DE++  E++GKG + +V R       QEYA K I
Sbjct: 230 SRFADEFECIEQMGKGGYGIVFRAKNKVDEQEYAVKRI 117
>16708
          Length = 1397

 Score = 35.8 bits (81), Expect = 0.039,   Method: Compositional matrix adjust.
 Identities = 19/47 (40%), Positives = 30/47 (63%), Gaps = 1/47 (2%)
 Frame = -1

Query: 116  CIQ-QILEAVLHCHQMGVVHRDLKPENLLLASKSKGAAVKLADFGLA 161
            CI  Q + A+ H H++GVVH D+K +N+L+ +       KL D+G+A
Sbjct: 1082 CIAGQXVCALEHIHELGVVHMDVKADNVLVDAHGN---CKLTDYGIA 951
>20513
          Length = 405

 Score = 35.8 bits (81), Expect = 0.047,   Method: Compositional matrix adjust.
 Identities = 15/37 (40%), Positives = 24/37 (64%), Gaps = 1/37 (2%)
 Frame = -1

Query: 237 EWDTVTPEA-KDLINKMLTINPAKRITASEALKHPWI 272
           EWD    +A  D +  ML  +P +R TA+++L+HPW+
Sbjct: 315 EWDPKDAKAFADFLAPMLEFDPEQRATAAQSLQHPWL 205
>18401
          Length = 463

 Score = 35.4 bits (80), Expect = 0.048,   Method: Compositional matrix adjust.
 Identities = 15/44 (34%), Positives = 23/44 (52%)
 Frame = -3

Query: 175 AGTPGYLSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDED 218
             T  Y +PEV+ +  +  P D+W+ G I++ L  GY  F   D
Sbjct: 449 VSTRHYRAPEVILELGWSHPCDVWSVGCIMFELYTGYTLFQTHD 318
>00638
          Length = 1595

 Score = 35.4 bits (80), Expect = 0.053,   Method: Compositional matrix adjust.
 Identities = 11/32 (34%), Positives = 23/32 (71%)
 Frame = +2

Query: 108 YSEADASHCIQQILEAVLHCHQMGVVHRDLKP 139
           +++ D    + ++++A+  CH MG++HRD+KP
Sbjct: 407 FTDYDIRFYLYELMKALDFCHSMGIMHRDVKP 502
>20559
          Length = 430

 Score = 35.4 bits (80), Expect = 0.062,   Method: Composition-based stats.
 Identities = 24/78 (30%), Positives = 36/78 (46%)
 Frame = -2

Query: 13  EYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPN 72
           +Y+  E++G+G +  V +     T +  A K +              RE  + + LKH N
Sbjct: 372 KYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKHRN 193

Query: 73  IVRLHDSISEEGFHYLVF 90
           IVRLHD +  E    LVF
Sbjct: 192 IVRLHDVLHSERKLTLVF 139
>16350
          Length = 1108

 Score = 35.0 bits (79), Expect = 0.063,   Method: Compositional matrix adjust.
 Identities = 15/37 (40%), Positives = 24/37 (64%), Gaps = 1/37 (2%)
 Frame = +3

Query: 237 EWDTVTPEA-KDLINKMLTINPAKRITASEALKHPWI 272
           EWD    +A  D +  ML  +P +R TA+++L+HPW+
Sbjct: 729 EWDPKDAKAFADFLAPMLEFDPEQRATAAQSLQHPWL 839
>07836
          Length = 1478

 Score = 35.0 bits (79), Expect = 0.073,   Method: Compositional matrix adjust.
 Identities = 26/86 (30%), Positives = 42/86 (48%), Gaps = 11/86 (12%)
 Frame = -1

Query: 131  GVVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQ----AWFGFAGTPGYLSPEVL 186
             + HRD+K +N+L+    K     +AD GLA+    +      A     GT  Y++PEVL
Sbjct: 1172 AIAHRDIKSKNILV---KKNGTCCIADLGLAVRYISESNEVDVAPNPRQGTKRYMAPEVL 1002

Query: 187  RK-------DPYGKPVDMWACGVILY 205
                     D + K  DM+A G++++
Sbjct: 1001 EMLLNVKNFDAF-KQADMYAFGLVMW 927
>37602
          Length = 804

 Score = 34.3 bits (77), Expect = 0.12,   Method: Compositional matrix adjust.
 Identities = 23/75 (30%), Positives = 36/75 (48%), Gaps = 5/75 (6%)
 Frame = -1

Query: 109 SEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKSKGAAVKLADF-----GLAIE 163
           +E   +   ++ L+ + + H+ G +HRD+K  N+LL  +     VKLADF       +  
Sbjct: 225 TEPQIAFVCRETLKGLHYLHRRGKMHRDIKGANILLTEEGD---VKLADFWRVSSNHSHN 55

Query: 164 VQGDQQAWFGFAGTP 178
           VQ     W  F G P
Sbjct: 54  VQKKVFHWNAFIGWP 10
>21210
          Length = 518

 Score = 33.9 bits (76), Expect = 0.16,   Method: Compositional matrix adjust.
 Identities = 29/106 (27%), Positives = 48/106 (45%), Gaps = 8/106 (7%)
 Frame = +3

Query: 175 AGTPGYLSPEVLRKDP------YGKPVDMWACGVILYILLVGYPPF--WDEDQHRLYQQI 226
           AG   Y++PE  R DP      Y    D+W+ G+ L  L  G  P+  W     +L Q +
Sbjct: 3   AGCRPYMAPE--RIDPRASSHGYDVRSDVWSLGITLMELATGRFPYRKWVSIFDQLQQVV 176

Query: 227 KAGAYDFPSPEWDTVTPEAKDLINKMLTINPAKRITASEALKHPWI 272
           +  A   P       + +  + +NK LT +  +R   ++ L HP++
Sbjct: 177 RGVAPCLPHD--GAFSHDFVNFVNKCLTKDEKQRPKYNKLLAHPFV 308
>32359
          Length = 928

 Score = 33.1 bits (74), Expect = 0.24,   Method: Compositional matrix adjust.
 Identities = 22/62 (35%), Positives = 33/62 (53%), Gaps = 5/62 (8%)
 Frame = -1

Query: 20  LGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSA-----RDHQKLEREARICRLLKHPNIV 74
           +G G+F VV           Y AK+++T +L A     +D +   RE +I R L+H NIV
Sbjct: 406 IGNGSFGVV-----------YQAKLVDTSELVAIKKVLQDKRFKNRELQIMRKLEHQNIV 260

Query: 75  RL 76
           +L
Sbjct: 259 KL 254

 Score = 28.5 bits (62), Expect = 7.3,   Method: Compositional matrix adjust.
 Identities = 11/18 (61%), Positives = 15/18 (83%)
 Frame = -3

Query: 131 GVVHRDLKPENLLLASKS 148
           GV HRD+KP+NLLL  ++
Sbjct: 65  GVCHRDIKPQNLLLDPET 12
>26009
          Length = 886

 Score = 33.1 bits (74), Expect = 0.30,   Method: Compositional matrix adjust.
 Identities = 13/33 (39%), Positives = 23/33 (69%)
 Frame = +3

Query: 112 DASHCIQQILEAVLHCHQMGVVHRDLKPENLLL 144
           +A   ++Q++ A+   H   +VHRD+KPEN+L+
Sbjct: 714 EAKSVMKQLVSALDFMHSKQLVHRDIKPENVLI 812
>17516
          Length = 453

 Score = 32.3 bits (72), Expect = 0.41,   Method: Composition-based stats.
 Identities = 16/38 (42%), Positives = 24/38 (63%), Gaps = 1/38 (2%)
 Frame = -3

Query: 174 FAGTPGYLSPEV-LRKDPYGKPVDMWACGVILYILLVG 210
            AGTP Y++PEV L+K  Y    D+++  +IL+ L  G
Sbjct: 439 LAGTPVYMAPEVLLQKGQYDMKADVYSLAIILWELWYG 326
>22098
          Length = 1090

 Score = 32.3 bits (72), Expect = 0.48,   Method: Compositional matrix adjust.
 Identities = 16/42 (38%), Positives = 27/42 (64%), Gaps = 6/42 (14%)
 Frame = +2

Query: 173 GFAGTPGYLSPEVLR------KDPYGKPVDMWACGVILYILL 208
           G  GT  Y++PEVL       +D + + +DM+ACG++L+ L+
Sbjct: 11  GLVGTRRYMAPEVLEGAICFNRDSFLR-IDMYACGLVLWELM 133
>20160
          Length = 1277

 Score = 31.6 bits (70), Expect = 0.70,   Method: Compositional matrix adjust.
 Identities = 11/29 (37%), Positives = 20/29 (68%)
 Frame = +2

Query: 244 EAKDLINKMLTINPAKRITASEALKHPWI 272
           +A DLIN+ + ++P+ R   ++ LKH W+
Sbjct: 335 DAADLINRCIALDPSTRPVLADILKHKWM 421
>03106
          Length = 2384

 Score = 31.6 bits (70), Expect = 0.78,   Method: Compositional matrix adjust.
 Identities = 23/69 (33%), Positives = 32/69 (46%), Gaps = 1/69 (1%)
 Frame = +2

Query: 196 DMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEA-KDLINKMLT 254
           D+WA G + Y +     PF+       Y Q     +D PS   D  TPE    L+  ML 
Sbjct: 32  DVWAAGAVAYEIFGASNPFYSRLDSACYSQ-----HDLPSLPGD--TPEGVVRLVTSMLE 190

Query: 255 INPAKRITA 263
            +PA+R +A
Sbjct: 191 RDPAQRPSA 217
>03294
          Length = 1684

 Score = 31.6 bits (70), Expect = 0.85,   Method: Compositional matrix adjust.
 Identities = 28/109 (25%), Positives = 47/109 (43%), Gaps = 25/109 (22%)
 Frame = -1

Query: 194  PVDMWACGVILYILLVGYPPF-WDEDQHRLYQQI---------------KAGAYDFPSPE 237
            PVD+W+ G I   +L+  P F  D +  +L++                 K  A++   P 
Sbjct: 1675 PVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIFRIIGTPTEQTWPEFHKLPAFNGMFPL 1496

Query: 238  W------DTVT---PEAKDLINKMLTINPAKRITASEALKHPWICQRST 277
            W      +T+T       DLI + L  +PA+RI+  + L+H +     T
Sbjct: 1495 WKEGKLSETLTDLDSLGLDLIERTLKCDPAQRISCKKMLQHAYFLNVDT 1349
>35032
          Length = 465

 Score = 31.6 bits (70), Expect = 0.90,   Method: Composition-based stats.
 Identities = 11/26 (42%), Positives = 19/26 (73%)
 Frame = +3

Query: 247 DLINKMLTINPAKRITASEALKHPWI 272
           DL+ ++L  +P+KR+T   AL HP++
Sbjct: 147 DLVKRLLNYDPSKRLTPXXALAHPFL 224
>21800
          Length = 855

 Score = 31.2 bits (69), Expect = 1.00,   Method: Compositional matrix adjust.
 Identities = 19/65 (29%), Positives = 33/65 (50%), Gaps = 3/65 (4%)
 Frame = +2

Query: 84  GFHYLVFDLVTGGELFEDIVAREYYS--EADASHCIQQILEAVLHCH-QMGVVHRDLKPE 140
           G H  +   V G  L + I+   Y      +    I+Q+LE + + H +  ++H D+KPE
Sbjct: 545 GTHVCMVFEVLGYNLLKLIIRSNYQGIPVHNVKLIIRQVLEGLNYLHAKCNIIHTDIKPE 724

Query: 141 NLLLA 145
           N+L+ 
Sbjct: 725 NILIC 739
>14104
          Length = 573

 Score = 30.8 bits (68), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 10/36 (27%), Positives = 22/36 (61%)
 Frame = +1

Query: 237 EWDTVTPEAKDLINKMLTINPAKRITASEALKHPWI 272
           ++    P+A   +   L ++PA+R+T  + L+HP++
Sbjct: 76  KFSNAAPQAMSFMQSCLKMDPAERLTCHQLLQHPYM 183
>13305
          Length = 549

 Score = 30.4 bits (67), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 15/51 (29%), Positives = 28/51 (54%), Gaps = 1/51 (1%)
 Frame = +2

Query: 180 YLSPEVLRKDPYGKPVDMWACGVILY-ILLVGYPPFWDEDQHRLYQQIKAG 229
           +++ E L  + Y    D+W+ GV+L+ I  +G  P+   D  +L+  +K G
Sbjct: 23  WMAVESLFNNTYTTQSDVWSFGVVLWEIFTLGGTPYSSTDTQQLFAFLKDG 175
>33586
          Length = 551

 Score = 30.0 bits (66), Expect = 2.1,   Method: Compositional matrix adjust.
 Identities = 14/48 (29%), Positives = 25/48 (52%)
 Frame = +2

Query: 73  IVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
           IV LH +   EG  YL+ + + GG+LF  +     ++E D    + ++
Sbjct: 407 IVHLHYAFQTEGKLYLILEFLRGGDLFTRLSKEVMFTEEDVKFYLAEL 550
>22005
          Length = 873

 Score = 29.6 bits (65), Expect = 3.0,   Method: Compositional matrix adjust.
 Identities = 56/251 (22%), Positives = 92/251 (36%), Gaps = 61/251 (24%)
 Frame = +1

Query: 19  ELGKGAFSVVRRCMKIPTGQEYAAKIINTKKL----------SARDHQK-LEREARICRL 67
           ++G+GAF  V + +K         ++I  K+           ++ D Q   EREA +   
Sbjct: 4   DIGQGAFGRVSK-LKFLGLASLVGELIPEKRP*LL*KMLKEDASEDLQSDFEREASLMAD 180

Query: 68  LKHPNIVRLHDSISEEGFHYLVFDLVTGGEL--FEDIVAREYYS---------------- 109
             HPNIV+L    +      L+F+ ++ G+L  F  + + E Y+                
Sbjct: 181 FDHPNIVKLLGVCAIGKPMCLLFEFMSKGDLNDFLRLCSPENYNLPVSRSQNLVVDLEDG 360

Query: 110 ---EADASHC-----------------------IQQILEAVLHCHQMGVVHRDLKPENLL 143
              E +A  C                        QQI   + +  Q   VHRDL      
Sbjct: 361 LRVEVEAEECEKDTQSEDRDCSGMLXTKDQLYISQQISAGMAYLAQKDYVHRDLATR--- 531

Query: 144 LASKSKGAAVKLADFGLAIEV------QGDQQAWFGFAGTPGYLSPEVLRKDPYGKPVDM 197
               S+     ++DFGLA  V      +G +Q        P     E +    +    D+
Sbjct: 532 -TVXSRTT*S*ISDFGLARSVHSVDYYRGSEQDAIPIRWMP----LEAILYSKFSTQSDV 696

Query: 198 WACGVILYILL 208
           W+ GV+L+ +L
Sbjct: 697 WSFGVVLWEIL 729
>17011
          Length = 1371

 Score = 29.3 bits (64), Expect = 3.6,   Method: Compositional matrix adjust.
 Identities = 12/26 (46%), Positives = 17/26 (65%)
 Frame = +1

Query: 247 DLINKMLTINPAKRITASEALKHPWI 272
           DLI  ++T NP  R+T   AL HP++
Sbjct: 1   DLILDVVTFNPDHRLTPDLALSHPFL 78
>31232
          Length = 993

 Score = 28.9 bits (63), Expect = 5.8,   Method: Compositional matrix adjust.
 Identities = 10/28 (35%), Positives = 20/28 (71%)
 Frame = +2

Query: 420 GNLVEGMDFHRFYFENALSKSNKPIHTI 447
           G+++  +D +RFYF+N L+K +  ++ I
Sbjct: 332 GDILNTLDMYRFYFKNILNKMSDKVNFI 415
>32357
          Length = 625

 Score = 28.5 bits (62), Expect = 6.5,   Method: Compositional matrix adjust.
 Identities = 17/69 (24%), Positives = 36/69 (52%)
 Frame = -2

Query: 1   MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER 60
           M+   T      +Y+L +++G G+F  +   +   +G+E A K+    +L    H +L  
Sbjct: 471 MSVVPTDLLVNGKYRLMKKIGSGSFGEIYLGVHNTSGEEVAVKL----ELKNAKHPQLYY 304

Query: 61  EARICRLLK 69
           E+++ R+L+
Sbjct: 303 ESKLYRVLQ 277
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|27229101|ref|NP_081740.2| hypothetical protein
LOC70564 [Mus musculus]
         (218 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

02732                                                                 191   2e-49
03910                                                                  28   3.6  
18735                                                                  28   3.9  
>02732
          Length = 2083

 Score =  191 bits (485), Expect = 2e-49,   Method: Compositional matrix adjust.
 Identities = 101/189 (53%), Positives = 127/189 (67%), Gaps = 1/189 (0%)
 Frame = +1

Query: 23  TDMFLSKPRKAALEYLEDIDLKTLEKEPRTFKAKELWEKNGAVIMAVRRPGCFLCRAEAA 82
            + F+  P+ A L YL D  L TL   PR FKA ELWEK GAVIMAVRRPGC LCR EA 
Sbjct: 292 VNPFVPNPKPATLAYLADTTLTTLXDNPRQFKASELWEKTGAVIMAVRRPGCSLCREEAQ 471

Query: 83  DLMSLKPKLDELGVPLYAVVKEQVKREVEDFQPYFKGE-IFLDEKKKFYGPERRKMMFMG 141
           +L S++ +L    VPLYAV+ E +    E+F PY K + I+LD+++KFYGP+ R M F G
Sbjct: 472 ELSSIRAELQMRNVPLYAVIHETLG--AEEFAPYLKAKAIYLDKERKFYGPQERWMFFSG 645

Query: 142 LIRLGVWYNSFRAWNGGFSGNLEGEGFILGGVFVIGSGKQGILLEHREKEFGDRVNPLSV 201
            +R  VW N  R    G  GNLEGEG +LGGVFV+G G+QGIL EHREKE+GD  N   +
Sbjct: 646 FMRASVWSNFARNRQKGVDGNLEGEGRLLGGVFVVGPGQQGILFEHREKEWGDLANNTDI 825

Query: 202 LEAVKKIKL 210
           + AV+K+ +
Sbjct: 826 VTAVRKMTV 852

 Score = 38.9 bits (89), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 16/31 (51%), Positives = 23/31 (74%)
 Frame = +2

Query: 180 KQGILLEHREKEFGDRVNPLSVLEAVKKIKL 210
           +QGIL EHREKE+GD  N   ++ AV+K+ +
Sbjct: 2   QQGILFEHREKEWGDLANNTDIVTAVRKMTV 94
>03910
          Length = 617

 Score = 27.7 bits (60), Expect = 3.6,   Method: Compositional matrix adjust.
 Identities = 21/65 (32%), Positives = 35/65 (53%), Gaps = 1/65 (1%)
 Frame = +2

Query: 73  GCFLCRAEAADLMSLKPKLDELGVPLYAVVKEQV-KREVEDFQPYFKGEIFLDEKKKFYG 131
           GC L R   A ++S K KLD  G+ L   + ++  +R+    Q + +GEIF  +K+ +  
Sbjct: 239 GCPLRRINQAYVISTKTKLDIKGLKLPDRLNDEYFRRQKLRKQKHTEGEIFSTKKEVYAV 418

Query: 132 PERRK 136
            + RK
Sbjct: 419 SDERK 433
>18735
          Length = 612

 Score = 27.7 bits (60), Expect = 3.9,   Method: Compositional matrix adjust.
 Identities = 21/65 (32%), Positives = 35/65 (53%), Gaps = 1/65 (1%)
 Frame = -1

Query: 73  GCFLCRAEAADLMSLKPKLDELGVPLYAVVKEQV-KREVEDFQPYFKGEIFLDEKKKFYG 131
           GC L R   A ++S K KLD  G+ L   + ++  +R+    Q + +GEIF  +K+ +  
Sbjct: 396 GCPLRRINQAYVISTKTKLDIKGLKLPDRLNDEYFRRQKLRKQKHTEGEIFSTKKEVYAV 217

Query: 132 PERRK 136
            + RK
Sbjct: 216 SDERK 202
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|63486962|ref|XP_130319.5| PREDICTED:
tetratricopeptide repeat domain 21B isoform 1 [Mus musculus]
         (1315 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

22802                                                                 194   2e-49
03857                                                                  30   7.4  
>22802
          Length = 509

 Score =  194 bits (494), Expect = 2e-49,   Method: Compositional matrix adjust.
 Identities = 89/168 (52%), Positives = 124/168 (73%)
 Frame = -1

Query: 419 LNDVVNTHFSHLEDLPLGIQYFEKLNPDFLLEVVTEYLNLCPIQPAGPGQPLSPVLRRCS 478
           +N+ +  HF+ ++ LPLGIQY+  LNPDFLL+VV  YL   P  P   GQ +SP+L+RC 
Sbjct: 506 VNEAIELHFAGIKGLPLGIQYYVLLNPDFLLQVVRNYLQFAPQVPVQTGQAVSPILKRCH 327

Query: 479 SVLETIIRSVPGLPQAVFLMAKVKYLSGDTEAAYNNLQHCLEHSPSYAEAHLLMAQVYLS 538
            VL+ + R+VPGL +  +L AKVKYL+ D E+A + L+HCLE  P++++AH+LMAQ++L 
Sbjct: 326 QVLDPLTRAVPGLMEGXYLXAKVKYLAADVESAQSTLEHCLESDPTFSDAHILMAQIHLY 147

Query: 539 QDKVKLCSQSLELCLSYNFNVREYPLYHLIKAQSQKKMGEVAEAIKTL 586
           Q+  KL +QS+E+ LSYNF VRE+PLYHLI+A+  KK G+ AEA  TL
Sbjct: 146 QNNFKLANQSMEVGLSYNFEVREHPLYHLIRARILKKQGDTAEAAATL 3
>03857
          Length = 1696

 Score = 29.6 bits (65), Expect = 7.4,   Method: Compositional matrix adjust.
 Identities = 18/66 (27%), Positives = 28/66 (42%)
 Frame = +1

Query: 919 IMLELAQLYLAQEDLDASLRHCALLLQRDQDNEPATMLMADLMFRKQDYEQAVYHLQQLL 978
           + L  A   L     + +L +C  +L+ D DN  A           +DYE A+   Q+ L
Sbjct: 628 VSLNAAACCLKLNKYNEALEYCQEVLEADPDNSKAQYRQGQAHAGNKDYETALASFQKAL 807

Query: 979 DRKPDN 984
              PD+
Sbjct: 808 AANPDD 825
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|12963653|ref|NP_075860.1| protein (peptidyl-prolyl
cis/trans isomerase) NIMA-interacting 1 [Mus musculus]
         (165 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

01656                                                                 189   3e-49
04932                                                                  55   2e-08
37652                                                                  46   6e-06
28454                                                                  41   3e-04
26162                                                                  40   5e-04
12851                                                                  31   0.19 
10214                                                                  27   3.1  
00178                                                                  27   4.0  
33922                                                                  27   4.7  
08199                                                                  27   5.2  
>01656
          Length = 2498

 Score =  189 bits (481), Expect = 3e-49,   Method: Compositional matrix adjust.
 Identities = 94/154 (61%), Positives = 112/154 (72%)
 Frame = +2

Query: 11  WEKRMSRSSGRVYYFNHITNASQWERPSGGSTVGGSSKNGQGEPAKVRCSHLLVKHSQSR 70
           WE+++SRS+GR YY N  T  SQWE PS  + +            KV+ SHLLVKH  SR
Sbjct: 2   WEQKVSRSTGRAYYLNIHTKESQWEEPSQAAAMS----------EKVQASHLLVKHKGSR 151

Query: 71  RPSSWRQEKITRSKEEALELINGYIQKIKSGEEDFESLASQFSDCSSAKARGDLGPFSRG 130
           RPSS RQ+ ITR+KEEA+ L+NGYIQ+IKS +  F  LA ++SDCSS+K  GDLGPF RG
Sbjct: 152 RPSSHRQDTITRTKEEAITLLNGYIQQIKSDKATFAQLAEEYSDCSSSKRGGDLGPFGRG 331

Query: 131 QMQKPFEDASFALRTGEMSGPVFTDSGIHIILRT 164
           QMQKPFEDA+F L  GEMSG V TDSG+HIILRT
Sbjct: 332 QMQKPFEDATFNLAVGEMSGIVDTDSGVHIILRT 433
>04932
          Length = 1244

 Score = 54.7 bits (130), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 30/74 (40%), Positives = 48/74 (64%), Gaps = 6/74 (8%)
 Frame = -2

Query: 95   IQKIKSGEEDFESLASQFSDCSSAKARGDLGPFSRGQMQKPFEDASFALRTGEMSGPVFT 154
            I+K+KSG + F  +ASQ+S+   A++ GDLG  +RG M  PF++A+F L+   ++ PV+T
Sbjct: 1117 IEKLKSGMK-FNEVASQYSE-DKARSGGDLGWMTRGSMVGPFQEAAFQLQNSTVNDPVYT 944

Query: 155  D------SGIHIIL 162
            D       G H+I+
Sbjct: 943  DPPVKTVHGYHVIM 902
>37652
          Length = 229

 Score = 46.2 bits (108), Expect = 6e-06,   Method: Compositional matrix adjust.
 Identities = 20/36 (55%), Positives = 27/36 (75%)
 Frame = -3

Query: 3   DEEKLPPGWEKRMSRSSGRVYYFNHITNASQWERPS 38
           D  +LP GWE+R S +SGRV+Y NH+T  +QWE P+
Sbjct: 107 DPNELPEGWEERRS-ASGRVHYVNHVTRTTQWETPN 3
>28454
          Length = 472

 Score = 40.8 bits (94), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 15/38 (39%), Positives = 25/38 (65%)
 Frame = -2

Query: 4   EEKLPPGWEKRMSRSSGRVYYFNHITNASQWERPSGGS 41
           ++ LP GWE R+  S GR++Y +H+   + W+RP  G+
Sbjct: 312 DDPLPSGWEARVD-SHGRIFYIDHMNRTTTWQRPQVGT 202
>26162
          Length = 608

 Score = 39.7 bits (91), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 16/34 (47%), Positives = 24/34 (70%)
 Frame = +1

Query: 5   EKLPPGWEKRMSRSSGRVYYFNHITNASQWERPS 38
           + LP GWE+R+ +  GRVYY +H T  + W+RP+
Sbjct: 172 QPLPAGWERRIDQH-GRVYYVDHNTRTTTWQRPN 270

 Score = 36.2 bits (82), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 18/39 (46%), Positives = 23/39 (58%), Gaps = 3/39 (7%)
 Frame = +1

Query: 2   ADEEKLPP---GWEKRMSRSSGRVYYFNHITNASQWERP 37
            D + L P   GWEKR   ++GRVY+ NH    +QWE P
Sbjct: 376 VDNDPLGPLLDGWEKRTD-ATGRVYFVNHKNRTTQWEDP 489
>12851
          Length = 1291

 Score = 31.2 bits (69), Expect = 0.19,   Method: Compositional matrix adjust.
 Identities = 10/19 (52%), Positives = 14/19 (73%)
 Frame = +1

Query: 20  GRVYYFNHITNASQWERPS 38
           GR YY+N +T  S WE+P+
Sbjct: 358 GRTYYYNSVTKKSSWEKPN 414
>10214
          Length = 469

 Score = 27.3 bits (59), Expect = 3.1,   Method: Compositional matrix adjust.
 Identities = 9/24 (37%), Positives = 15/24 (62%)
 Frame = +1

Query: 12  EKRMSRSSGRVYYFNHITNASQWE 35
           E R  R + R+Y+ +H+TN   W+
Sbjct: 331 EMRCCRKAFRIYFKDHVTNQEVWQ 402
>00178
          Length = 944

 Score = 26.9 bits (58), Expect = 4.0,   Method: Compositional matrix adjust.
 Identities = 10/20 (50%), Positives = 13/20 (65%)
 Frame = -3

Query: 18  SSGRVYYFNHITNASQWERP 37
           + GR YY+N  T  S WE+P
Sbjct: 114 TDGRSYYYNSRTMESTWEKP 55
>33922
          Length = 832

 Score = 26.6 bits (57), Expect = 4.7,   Method: Compositional matrix adjust.
 Identities = 11/31 (35%), Positives = 21/31 (67%)
 Frame = -3

Query: 87  ALELINGYIQKIKSGEEDFESLASQFSDCSS 117
           A+E  NG++++I+   +  +SLA Q +D S+
Sbjct: 371 AIEDENGFVEQIRQALQGLQSLADQSTDGST 279
>08199
          Length = 688

 Score = 26.6 bits (57), Expect = 5.2,   Method: Compositional matrix adjust.
 Identities = 10/20 (50%), Positives = 15/20 (75%)
 Frame = +3

Query: 6   KLPPGWEKRMSRSSGRVYYF 25
           K+ PG  KR+ ++ GRV+YF
Sbjct: 222 KIYPGHGKRVIKTDGRVFYF 281
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|157951598|ref|NP_033924.2| calpain 2 [Mus musculus]
         (700 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

16109                                                                 129   3e-49
18677                                                                 122   5e-28
28393                                                                  92   5e-19
03732                                                                  83   3e-16
12214                                                                  76   4e-14
30646                                                                  39   0.005
23206                                                                  35   0.11 
12911                                                                  32   0.93 
14945                                                                  31   1.3  
22063                                                                  31   1.6  
32442                                                                  30   3.3  
04643                                                                  28   9.0  
>16109
          Length = 1490

 Score =  129 bits (323), Expect(2) = 3e-49,   Method: Compositional matrix adjust.
 Identities = 91/324 (28%), Positives = 166/324 (51%), Gaps = 4/324 (1%)
 Frame = +3

Query: 377 YPNTFWMNPQYLIKLXXXXXXXXXXXRGCTFLVGLIQKHRRRQRKMGEDMHTIGFGIYEV 436
           Y  +FW NPQY IKL              + ++ L++   + +R   ED+ +IGF I+++
Sbjct: 387 YSRSFWTNPQYRIKLEDKDKDK------LSVVISLLEVTDKFERAT-EDV-SIGFVIFKL 542

Query: 437 P--EELTGQTNIHLGKNFF-LTTRARERSDTFINLREVLNRFKLPPGEYVLVPSTFEPHK 493
              +E  G+ +    +NF+  + +  + S  F   RE    F L  G YV++P TF+ + 
Sbjct: 543 KPGKEPIGKLD---SENFYEHSPQLVDTSGVFWPYRERSIHFSLETGSYVIIPCTFKANM 713

Query: 494 DGDFCIRVFSEKKADYQAVXXXXXXXXXXXXXXXXXXXXGFRRLFVQLAGEDAEISAFEL 553
           + +F +R+FSE +A  +                         RLF +  G  +++ A  L
Sbjct: 714 EAEFHLRIFSETEATPEPTEEPIGPTEEIEPEPVGL----IERLFHKHQGPSSKVDAARL 881

Query: 554 QTILRRVLAKRQDI-KSDGFSIETCKIMVDMLDEDGSGKLGLKEFYILWTKIQKYQKIYR 612
           Q IL    AKR++  K DG+S+ETC+ ++ +LD D +G+L L+    +W  ++ + K + 
Sbjct: 882 QRILDE--AKREEYNKEDGYSLETCRCLLSLLDRDITGRLSLEAVKTIWNYVKVWTKAFH 1055

Query: 613 EIDVDRSGTMNSYEMRKALEEAGFKLPCQLHQVIVARFADDELIIDFDNFVRCLVRLETL 672
             DV +   ++++E++   ++ GF +  ++ + IV R+ D++  I  D+F++   R+  L
Sbjct: 1056TTDVSKDKLVDTFELKDLFKKIGFTIDSEVLKRIVCRYGDEDGKIHEDDFLQSFCRVLAL 1235

Query: 673 FKIFKQLDPENTGTIQLNLASWLS 696
           + IFK+    + G I  NL+ WLS
Sbjct: 1236YHIFKK--KSSDGLITQNLSEWLS 1301

 Score = 85.5 bits (210), Expect(2) = 3e-49,   Method: Compositional matrix adjust.
 Identities = 47/125 (37%), Positives = 70/125 (56%), Gaps = 9/125 (7%)
 Frame = +1

Query: 258 LVKGHAYSVTGAEEVESSGSLQKLIRIRNPWGQVEWTGKWNDNCPSWNTVDPEVRANLTE 317
           L + HAYS+   + V   G    L+ +RNP+G+ EW G W+D    W+ +    R+  TE
Sbjct: 4   LYEMHAYSIIRMKTVTYRGKKTLLLLLRNPFGRGEWNGAWSDKSKEWSELRVSERS--TE 177

Query: 318 ---RQEDGEFWMSFSDFLRHYSRLEICNLTPDTLTCD------SYKKWKLTKMDGNWRRG 368
              R+++GEFWMS  DF  ++  +E+C+L+ D LT +        K WK T+  G W RG
Sbjct: 178 ALLRRDNGEFWMSVEDFKANFDEVELCHLSVDALTAERELASGGKKAWKRTEFTGQWIRG 357

Query: 369 STAGG 373
            +AGG
Sbjct: 358 VSAGG 372
>18677
          Length = 754

 Score =  122 bits (306), Expect = 5e-28,   Method: Compositional matrix adjust.
 Identities = 74/228 (32%), Positives = 122/228 (53%), Gaps = 1/228 (0%)
 Frame = +2

Query: 450 KNFFLTTRARERSDTFINLREVLNRFKLPPGEYVLVPSTFEPHKDGDFCIRVFSEKKADY 509
           KN  L  R   RS T++  RE   RF++PPG+YV+VPSTF PH++  F +R+F+EK A+ 
Sbjct: 56  KNALLLAR---RSGTYVFYRECTKRFEMPPGDYVIVPSTFHPHEEAKFMMRLFTEKFAES 226

Query: 510 QAVXXXXXXXXXXXXXXXXXXXXGFRRLFVQLAGEDAEISAFELQTILRRVLAKRQDIKS 569
           + V                        +F +  G D+ +   ELQ  L  V    +D+K 
Sbjct: 227 R-VMEEDDEAPEDDITPVMSPKDFVSDIFHKHCGSDSRLDPGELQKFLEDV--SDEDVKQ 397

Query: 570 D-GFSIETCKIMVDMLDEDGSGKLGLKEFYILWTKIQKYQKIYREIDVDRSGTMNSYEMR 628
              F+IE C+ ++ M+DE+ SG+L   E   LW +I+ Y++++ + D +RSG +++YE+ 
Sbjct: 398 RLKFNIEQCRSLLPMMDENRSGRLEFPEAKRLWKEIKAYREVFLQFDKNRSGLVDTYELG 577

Query: 629 KALEEAGFKLPCQLHQVIVARFADDELIIDFDNFVRCLVRLETLFKIF 676
               + GF +   +   IV R+ D    I  ++FV  ++RL  L+ I+
Sbjct: 578 NMFSKLGFPVTRPVLTSIVRRYGDRRNQISLEDFVVVILRLIQLYNIY 721
>28393
          Length = 726

 Score = 92.4 bits (228), Expect = 5e-19,   Method: Compositional matrix adjust.
 Identities = 61/192 (31%), Positives = 93/192 (48%), Gaps = 1/192 (0%)
 Frame = -3

Query: 319 QEDGEFWMSFSDFLRHYSRLEICNLTPDTLTCDSYKKWKLTKMDGNWRRGSTAGGCRNYP 378
           +EDGEFWM+F DF +H+ +  IC +   +    S K W      G W+    AGGC N  
Sbjct: 718 EEDGEFWMTFEDFCKHFHQTAICRVVNTSFFSLS-KMWHEGLSHGAWKGPDRAGGCPNNK 542

Query: 379 NTFWMNPQYLIKLXXXXXXXXXXXRGCTFLVGLIQKHRRRQRKMGEDMHTIGFGIYEVPE 438
            +F  NPQ +  +               F+  L+QK  R   K G    TIGF + +V  
Sbjct: 541 ESFLKNPQXVFDVGDDEE----------FMAQLMQKSTR--DKDGSANKTIGFTVLKV-- 404

Query: 439 ELTGQTNIHLGKNFFLTTRARERSDTFINLREVLNRF-KLPPGEYVLVPSTFEPHKDGDF 497
           EL  +  IH      L+ + R  S  + + R +  R   +  G YV+VPSTFEP+++ +F
Sbjct: 403 ELNRRYRIHD-----LSLQERATSTVYRDSRSIFLRHGPMKKGRYVIVPSTFEPNQEAEF 239

Query: 498 CIRVFSEKKADY 509
            +RV++    ++
Sbjct: 238 LLRVYTTDSNNF 203
>03732
          Length = 1114

 Score = 83.2 bits (204), Expect = 3e-16,   Method: Compositional matrix adjust.
 Identities = 41/126 (32%), Positives = 72/126 (57%), Gaps = 1/126 (0%)
 Frame = -1

Query: 572  FSIETCKIMVDMLDEDGSGKLGLKEFYILWTKIQKYQKIYREIDVDRSGTMNSYEMRKAL 631
            F+ ET ++M+ M D D SG +  +EF  LW  +  +Q  +R  D D SG+++  E++ AL
Sbjct: 1000 FNPETVRLMIGMFDRDNSGTINFQEFQALWKYVTDWQNCFRSYDRDNSGSIDRNELKNAL 821

Query: 632  EEAGFKLPCQLHQVIVARF-ADDELIIDFDNFVRCLVRLETLFKIFKQLDPENTGTIQLN 690
               G++L  +   V+V +F    +  + FD+F++C V L+TL   F+  D +  G IQ++
Sbjct: 820  TGFGYRLSDRFFDVLVKKFDRQGKGTVAFDDFIQCCVVLQTLTTSFRTHDQDQDGWIQIS 641

Query: 691  LASWLS 696
               +L+
Sbjct: 640  YEQFLT 623
>12214
          Length = 654

 Score = 76.3 bits (186), Expect = 4e-14,   Method: Composition-based stats.
 Identities = 37/126 (29%), Positives = 70/126 (55%), Gaps = 1/126 (0%)
 Frame = -3

Query: 576 TCKIMVDMLDEDGSGKLGLKEFYILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAG 635
           T ++M+ M D D SG + + EF  LW  IQ+++  +   D +RSG++   E++ A ++ G
Sbjct: 652 TSRLMIGMFDRDMSGTIDINEFQSLWQYIQQWRSTFERYDSNRSGSIEGNELQAAYQQMG 473

Query: 636 FKLPCQLHQVIVARFAD-DELIIDFDNFVRCLVRLETLFKIFKQLDPENTGTIQLNLASW 694
           F +  +  Q ++ +F       +  DNF++  V L++L   F+Q D  +TG + +    +
Sbjct: 472 FNVSPRFVQTVLYKFDHFGRRSLTLDNFIQSCVMLKSLTDAFRQRDTGSTGVVNMAYEDF 293

Query: 695 LSFSVL 700
           L+ +VL
Sbjct: 292 LTMAVL 275
>30646
          Length = 476

 Score = 39.3 bits (90), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 44/172 (25%), Positives = 70/172 (40%), Gaps = 4/172 (2%)
 Frame = +3

Query: 324 FWMSFSDFLRHYSRLEICNLTPDTLTCDSYKKW--KLTKMDGNWRRGSTAGGCRNYPNTF 381
           FW+   DF+ ++ +  IC+LTPD    D    +   +T + G W RG TA G R      
Sbjct: 3   FWICLEDFMTYFDQTTICSLTPD-FDMDGSSDFLNYVTNVYGEW-RGETAAGFRQK---- 164

Query: 382 WMNPQYLIKLXXXXXXXXXXXRGCTFLVGLIQKHRRRQRKMGEDMHTIGFGIYEVPEELT 441
             NP+ L  +                +V LIQ    R  +  E+   +   +Y+V     
Sbjct: 165 LQNPRILFTVPESAGAEV------PVVVQLIQW---RDSRSAENFQ-VRCDLYKV----- 299

Query: 442 GQTNIHLGKNFFLTTRAR--ERSDTFINLREVLNRFKLPPGEYVLVPSTFEP 491
                 LG +  +   A   E ++++    +   R K+ PG Y +VPS   P
Sbjct: 300 ------LGDDGEVAVLASMGENTNSYCPETQCSFRHKVTPGTYAVVPSPLTP 437
>23206
          Length = 1611

 Score = 35.0 bits (79), Expect = 0.11,   Method: Compositional matrix adjust.
 Identities = 24/76 (31%), Positives = 35/76 (46%), Gaps = 1/76 (1%)
 Frame = -3

Query: 134 NYAGIFHFQFWQYGEWVEVVVDDRLP-TKDGELLFVHSAEGSEFWSALLEKAYAKINGCY 192
           N  G +  + +  G W +++VDD LP  ++ +LL   +    E W  LL KA  K+    
Sbjct: 868 NPHGKYIVRLFWMGCWRKILVDDLLPFDENDQLLLPATTLSHELWPMLLAKAIIKVASL- 692

Query: 193 EALSGGATTEGFEDFT 208
              SGG     F D T
Sbjct: 691 -DYSGGNPGAEFGDIT 647
>12911
          Length = 469

 Score = 32.0 bits (71), Expect = 0.93,   Method: Composition-based stats.
 Identities = 13/56 (23%), Positives = 31/56 (55%), Gaps = 1/56 (1%)
 Frame = +1

Query: 455 TTRARERSDTFINLREVLNRF-KLPPGEYVLVPSTFEPHKDGDFCIRVFSEKKADY 509
           + + +  S  + + R +  R+  +  G YV+VPSTFE  ++  + +R+++    ++
Sbjct: 1   SVQEKTTSTVYRDSRSIFLRYGPVSRGRYVVVPSTFEAGQEAQYLLRIYTSASNNF 168
>14945
          Length = 1337

 Score = 31.2 bits (69), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 21/89 (23%), Positives = 45/89 (50%), Gaps = 8/89 (8%)
 Frame = +1

Query: 605 QKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPCQLHQVIVARFADDEL-IIDFDNFV 663
           Q+ ++ +   D D SGT+++ E++ A+   GF+   +  + ++A    +    IDF++F+
Sbjct: 112 QEIREAFDLFDADGSGTIDAKELKVAMRALGFEPKKEEIKKMIAEIDKEGTGTIDFNDFL 291

Query: 664 RCLVR-------LETLFKIFKQLDPENTG 685
             + +        E + K F+  D + TG
Sbjct: 292 TIMTQKMSEKDAKEEILKAFRLFDDDETG 378
>22063
          Length = 688

 Score = 31.2 bits (69), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 21/89 (23%), Positives = 45/89 (50%), Gaps = 8/89 (8%)
 Frame = +3

Query: 605 QKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPCQLHQVIVARFADDEL-IIDFDNFV 663
           Q+ ++ +   D D SGT+++ E++ A+   GF+   +  + ++A    +    IDF++F+
Sbjct: 171 QEIREAFDLFDADGSGTIDAKELKVAMRALGFEPKKEEIKKMIAEIDKEGTGTIDFNDFL 350

Query: 664 RCLVR-------LETLFKIFKQLDPENTG 685
             + +        E + K F+  D + TG
Sbjct: 351 TIMTQKMSEKDAKEEILKAFRLFDDDETG 437
>32442
          Length = 221

 Score = 30.0 bits (66), Expect = 3.3,   Method: Composition-based stats.
 Identities = 19/56 (33%), Positives = 29/56 (51%), Gaps = 8/56 (14%)
 Frame = +2

Query: 204 FEDFTGGIAEWYELRKPPP--------NLFKIIQKALEKGSLLGCSIDITSAADSE 251
            EDFTGG+A+  +L K            LF  +QK +++ SL+  SI   S+ + E
Sbjct: 2   LEDFTGGVADTLDLLKMEVANKVEERIALFSRMQKEVDRRSLMAASIPAASSEEME 169
>04643
          Length = 1881

 Score = 28.5 bits (62), Expect = 9.0,   Method: Compositional matrix adjust.
 Identities = 15/44 (34%), Positives = 21/44 (47%)
 Frame = +2

Query: 559 RVLAKRQDIKSDGFSIETCKIMVDMLDEDGSGKLGLKEFYILWT 602
            + A  + +  D  S E    +V   D DG+GK+  KEF   WT
Sbjct: 23  EIKAHVRALTGDDMSEEALDNLVSKSDADGNGKINYKEFLASWT 154
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|28893485|ref|NP_796319.1| mitogen-activated protein
kinase associated protein 1 [Mus musculus]
         (522 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

10697                                                                 192   3e-49
27674                                                                  30   1.9  
>10697
          Length = 1382

 Score =  192 bits (488), Expect = 3e-49,   Method: Compositional matrix adjust.
 Identities = 97/192 (50%), Positives = 134/192 (69%)
 Frame = -2

Query: 322  QYRLEKQSEPNIAVDLESTLESQNAWEFCLVRENSSRADGVFEEDSQIDIATVQDMLSSH 381
            +Y LEKQSEP ++VDL++ L   +  EFCLVRENS+R D   E+  Q +++ V D L+SH
Sbjct: 1378 RYNLEKQSEPGVSVDLDTNLVHMDTMEFCLVRENSTRGDT--EDSHQSEMSNVADSLTSH 1205

Query: 382  HYKSFKVSMIHRLRFTTDVQLGISGDKVEIDPVTNQKASTKFWIKQKPISIDCDLLCACD 441
             YKS+ V+M+HRLR  T+VQLGISG+KVEIDPV  Q  ++   I+QKP++ + D +  CD
Sbjct: 1204 QYKSYMVTMVHRLRANTEVQLGISGEKVEIDPV--QIRNSIRLIRQKPVTHEADSIADCD 1031

Query: 442  LAEEKSPSHAVFKLTYLSSHDYKHLYFESDAATVSEIVLKVNYILESRASTARADYLAQK 501
            + E+KS   AVF+LTYL+ H+YKH  FESD    +EIV K+  ILE R S AR ++++ +
Sbjct: 1030 ILEKKSNGRAVFRLTYLTEHNYKHHDFESDNVIATEIVHKLKNILELRLSPARKEFISAQ 851

Query: 502  QRKLNRRTSFSF 513
             RKL +R S  F
Sbjct: 850  DRKLRKRDSLKF 815
>27674
          Length = 551

 Score = 30.4 bits (67), Expect = 1.9,   Method: Compositional matrix adjust.
 Identities = 19/84 (22%), Positives = 36/84 (42%)
 Frame = -2

Query: 437 LCACDLAEEKSPSHAVFKLTYLSSHDYKHLYFESDAATVSEIVLKVNYILESRASTARAD 496
           L  C++A+++SP H +FK  +   H + +L+     +    +  ++ YI       AR  
Sbjct: 382 LFRCEMAQKRSPPHVIFKFPWY-RHTFFNLF*NRALSNPGNLDFRLRYISSFV*WLAREH 206

Query: 497 YLAQKQRKLNRRTSFSFQKEKKSG 520
            + +     +R   F F   K  G
Sbjct: 205 VVPEVVGSASRVVVFPFMHIKGDG 134
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|40254160|ref|NP_083795.2| RAP2A, member of RAS
oncogene family [Mus musculus]
         (183 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

07580                                                                 184   4e-49
00858                                                                 140   2e-34
06994                                                                  84   2e-20
26536                                                                  91   3e-19
24619                                                                  90   6e-19
36482                                                                  88   2e-18
19046                                                                  87   4e-18
34468                                                                  80   5e-16
08428                                                                  79   9e-16
33374                                                                  73   8e-14
14456                                                                  71   3e-13
11257                                                                  70   5e-13
32723                                                                  69   1e-12
01398                                                                  67   3e-12
11728                                                                  67   3e-12
07465                                                                  65   1e-11
13750                                                                  63   8e-11
33380                                                                  62   1e-10
18509                                                                  59   9e-10
31291                                                                  58   2e-09
17511                                                                  58   3e-09
01972                                                                  55   2e-08
19006                                                                  54   3e-08
30760                                                                  54   4e-08
26083                                                                  53   6e-08
34359                                                                  53   7e-08
01095                                                                  52   1e-07
19656                                                                  52   2e-07
29380                                                                  49   9e-07
13745                                                                  48   3e-06
34597                                                                  46   7e-06
12339                                                                  46   7e-06
31928                                                                  41   3e-04
10708                                                                  38   0.002
09204                                                                  37   0.007
31932                                                                  36   0.011
18949                                                                  33   0.075
15662                                                                  27   6.4  
35581                                                                  26   9.0  
>07580
          Length = 921

 Score =  184 bits (467), Expect(2) = 4e-49,   Method: Compositional matrix adjust.
 Identities = 82/140 (58%), Positives = 111/140 (79%)
 Frame = +3

Query: 26  GTFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAGTEQFASMRDLYIKNGQGFILVYSLV 85
           G F+EKYDPTIED YRK++EVD    +LEILDTAGTEQF +MRDLY+KNGQGF+L YS+ 
Sbjct: 129 GIFVEKYDPTIEDSYRKQVEVDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFLLAYSIT 308

Query: 86  NQQSFQDIKPMRDQIIRVKRYEKVPVILVGNKVDLESEREVSSNEGRALAEEWGCPFMET 145
            Q +F D++ +R+QI+RVK  + VP++LVGNK DLE ER V  ++G+ LA  + C F+ET
Sbjct: 309 AQSTFNDLQELREQILRVKDTDDVPMLLVGNKCDLEDERVVGKDQGQGLARSFSCAFLET 488

Query: 146 SAKSKTMVDELFAEIVRQMN 165
           SAK++  V+E+F ++VRQ+N
Sbjct: 489 SAKARINVNEIFMDLVRQIN 548

 Score = 26.9 bits (58), Expect(2) = 4e-49,   Method: Compositional matrix adjust.
 Identities = 14/31 (45%), Positives = 14/31 (45%)
 Frame = +2

Query: 1  MREYXXXXXXXXXXXXXALTVQFVTGTFIEK 31
          MREY             ALTVQFV G F  K
Sbjct: 53 MREYKLVVLGSGGVGKSALTVQFVQGDFCGK 145
>00858
          Length = 1658

 Score =  140 bits (354), Expect = 2e-34,   Method: Compositional matrix adjust.
 Identities = 70/164 (42%), Positives = 107/164 (65%)
 Frame = -2

Query: 1    MREYXXXXXXXXXXXXXALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAG 60
            M EY             ALT+Q     F+E+YDPT ED  RK++ +D    +L+ILDTAG
Sbjct: 1597 MTEYKLVVVGAGGVGKSALTIQLXQNHFVEEYDPTXEDSXRKQVVIDGETCLLDILDTAG 1418

Query: 61   TEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIIRVKRYEKVPVILVGNKVDL 120
             E+ ++MRD  ++ G+GF+ V+++ N +SF+DI   R+QI RVK  ++VP++LVGNKVDL
Sbjct: 1417 QEEXSAMRDQCMRTGEGFLCVFAVXNLKSFEDINQYREQIKRVKDADEVPMVLVGNKVDL 1238

Query: 121  ESEREVSSNEGRALAEEWGCPFMETSAKSKTMVDELFAEIVRQM 164
               R V   +G+ +AE +  P++ETSAK++  VD+ F  +VR++
Sbjct: 1237 PI-RNVEQRQGKHMAELYHIPYVETSAKTRQGVDDAFYTLVREI 1109
>06994
          Length = 429

 Score = 84.3 bits (207), Expect(2) = 2e-20,   Method: Compositional matrix adjust.
 Identities = 44/101 (43%), Positives = 55/101 (54%), Gaps = 32/101 (31%)
 Frame = +1

Query: 26  GTFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAG------------------------- 60
           G   +KYDPTIED YRK++EVD    +LEILDTAG                         
Sbjct: 124 GFLWKKYDPTIEDSYRKQVEVDGQQCMLEILDTAGTVHASHSNACVHGSLHAFVGTVTPL 303

Query: 61  -------TEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIK 94
                  TEQF +MRDLY+KNGQGF+L YS+  Q +F D++
Sbjct: 304 GRDALLNTEQFTAMRDLYMKNGQGFLLAYSITAQSTFNDLQ 426

 Score = 31.2 bits (69), Expect(2) = 2e-20,   Method: Compositional matrix adjust.
 Identities = 15/31 (48%), Positives = 16/31 (51%)
 Frame = +3

Query: 1  MREYXXXXXXXXXXXXXALTVQFVTGTFIEK 31
          MREY             ALTVQFV G F+EK
Sbjct: 48 MREYKLVVLGSGGVGKSALTVQFVQGIFVEK 140
>26536
          Length = 829

 Score = 90.5 bits (223), Expect = 3e-19,   Method: Compositional matrix adjust.
 Identities = 42/110 (38%), Positives = 71/110 (64%)
 Frame = +2

Query: 55  ILDTAGTEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIIRVKRYEKVPVILV 114
            LDTAG E+++SMR+ Y ++G GFI+VYS+ +  SFQ+ + +   + R +    +  +L 
Sbjct: 140 FLDTAGQEEYSSMREHYTRSGDGFIVVYSVTDVTSFQEAEAVFRWLTRFQDETSIHAVLC 319

Query: 115 GNKVDLESEREVSSNEGRALAEEWGCPFMETSAKSKTMVDELFAEIVRQM 164
           GNK DL S+R+V+  EGR +A+  G  + ETSAK+   V +++  ++R +
Sbjct: 320 GNKTDLTSDRKVTPEEGRKMADRLGMLYFETSAKTGDNVSQVYHGLLRSI 469

 Score = 42.7 bits (99), Expect = 9e-05,   Method: Compositional matrix adjust.
 Identities = 18/33 (54%), Positives = 24/33 (72%)
 Frame = +2

Query: 18  ALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSP 50
           +LT++F   TF++ YDPTIED YRK I+V   P
Sbjct: 530 SLTIRFTQDTFLDVYDPTIEDSYRKMIQVSGQP 628
>24619
          Length = 509

 Score = 89.7 bits (221), Expect = 6e-19,   Method: Compositional matrix adjust.
 Identities = 47/110 (42%), Positives = 73/110 (66%), Gaps = 1/110 (0%)
 Frame = -2

Query: 62  EQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIIRVKRYEKVPVILVGNKVDLE 121
           E+F++MR+ Y++ G GF+LV+S+++ QSF+++     QI+RVK  +  P+IL  NKVDL 
Sbjct: 505 EEFSAMREQYMRKGDGFLLVFSVIDYQSFENMVNFHTQILRVKDRDTYPMILCANKVDLV 326

Query: 122 SEREVSSNEGRALAEEWGCPFMETSAKSKTM-VDELFAEIVRQMNYAAQP 170
            +R+VS  + R LA     P++ETSAK   + VD  F ++VR +   AQP
Sbjct: 325 HQRKVSEEQVRDLATRLRIPYIETSAKDPPLNVDLAFHQVVRVIR--AQP 182
>36482
          Length = 686

 Score = 88.2 bits (217), Expect = 2e-18,   Method: Compositional matrix adjust.
 Identities = 50/154 (32%), Positives = 85/154 (55%), Gaps = 3/154 (1%)
 Frame = +2

Query: 19  LTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAGTEQFASMRDLYIKNGQGF 78
           LTV+F+T  FI +Y PT+E  Y+    ++     LEILDTAG   +   ++ Y      F
Sbjct: 2   LTVRFLTRRFIGEYCPTLESVYKYHTVIEDDDVRLEILDTAGQGTYP-WKEGYALWADCF 178

Query: 79  ILVYSLVNQQSFQDIKPMRDQIIRVKRYEKVPVILVGNKVDLESEREVSSNEGRALAEEW 138
           + VYS+ ++QS++++  ++ Q+  V++   +  +L  NK DL  +R+V+  EG  LAEE 
Sbjct: 179 VFVYSINDRQSYEELVQVKRQVESVRKSTSLTAVLAANKTDLLHDRQVTQKEGEDLAEEI 358

Query: 139 GCPFMETSAKSKTMVD---ELFAEIVRQMNYAAQ 169
           GC   E SA   + ++    +F ++ R+     Q
Sbjct: 359 GCRLYEVSASEGSQMEAITSMFHDLYREFRKHKQ 460
>19046
          Length = 445

 Score = 87.0 bits (214), Expect = 4e-18,   Method: Compositional matrix adjust.
 Identities = 46/110 (41%), Positives = 72/110 (65%), Gaps = 1/110 (0%)
 Frame = -2

Query: 62  EQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIIRVKRYEKVPVILVGNKVDLE 121
           E+F++MR+ Y++ G GF+LV+S+ + +SF+++     QI+RVK  +  P+IL  NKVDL 
Sbjct: 441 EEFSAMREQYMRKGDGFLLVFSVTDFRSFENMANFHTQILRVKDRDSYPMILCANKVDLV 262

Query: 122 SEREVSSNEGRALAEEWGCPFMETSAKSKTM-VDELFAEIVRQMNYAAQP 170
            +R+VS  + R LA     P++ETSAK   + VD  F ++VR +   AQP
Sbjct: 261 HQRKVSEEQVRDLATRLRIPYIETSAKDPPLNVDLAFHQVVRVIR--AQP 118
>34468
          Length = 1502

 Score = 80.1 bits (196), Expect = 5e-16,   Method: Compositional matrix adjust.
 Identities = 51/151 (33%), Positives = 77/151 (50%), Gaps = 5/151 (3%)
 Frame = +1

Query: 19  LTVQFVTGTFIEKYDPTIE-DFYRKEIEVDSSPSVLEILDTAGTEQF-ASMRDLYIKNGQ 76
           LT +F  G F +K + TI  DF  K I+VDS    L++ DTAG E+F  SM   Y +N  
Sbjct: 541 LTYRFCLGKFPDKTEATIGVDFREKSIQVDSEHLKLQLWDTAGQERFRKSMVQHYYRNVH 720

Query: 77  GFILVYSLVNQQSFQDIKPMRDQIIRVKRYEKVPVILVGNKVDLESEREVSSNEGRALAE 136
             + VY +    SF+++    ++  R    + +P ILVGNK D+     V++N  +  A+
Sbjct: 721 AVVFVYDMTKMSSFENMPAWIEECDRHNLTKYIPRILVGNKCDVVERIAVNTNLAQKFAD 900

Query: 137 EWGCPFMETSAK---SKTMVDELFAEIVRQM 164
               P  ETSAK       VD +F  +  ++
Sbjct: 901 AHNMPLFETSAKDDEKANHVDAIFMTVAHKL 993
>08428
          Length = 1109

 Score = 79.3 bits (194), Expect = 9e-16,   Method: Compositional matrix adjust.
 Identities = 49/162 (30%), Positives = 85/162 (52%), Gaps = 1/162 (0%)
 Frame = -3

Query: 18   ALTVQFVTGTFIEKYDPTI-EDFYRKEIEVDSSPSVLEILDTAGTEQFASMRDLYIKNGQ 76
            ++ ++FVTG++    + TI   F  K + VD +    +I DTAG E+F ++  +Y +   
Sbjct: 1026 SIVLRFVTGSYRPSQESTIGASFMSKSLVVDGAGYRFQIWDTAGQEKFRALAPMYYRGAA 847

Query: 77   GFILVYSLVNQQSFQDIKPMRDQIIRVKRYEKVPVILVGNKVDLESEREVSSNEGRALAE 136
              ++VY +   ++F+ +K    Q +R      + + + GNK DLE  REV   + +  A 
Sbjct: 846  AAVIVYDVTRPRTFKSVKSW-IQELRSFGPPNIVLAIAGNKCDLEELREVVEKDAQEYAS 670

Query: 137  EWGCPFMETSAKSKTMVDELFAEIVRQMNYAAQPDKDDPCCS 178
                 F ETSA +   V+E+F E+ RQ+     P++D+P  S
Sbjct: 669  SISAIFGETSAMTAVNVEEMFTELARQL----PPEEDNPHPS 556
>33374
          Length = 489

 Score = 72.8 bits (177), Expect = 8e-14,   Method: Compositional matrix adjust.
 Identities = 41/118 (34%), Positives = 65/118 (55%)
 Frame = +1

Query: 39  FYRKEIEVDSSPSVLEILDTAGTEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRD 98
           F  + + +D +    EI DTAG E++ S+  +Y +  Q  I+VY + NQ +F   K    
Sbjct: 139 FLTQTVCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNQDTFGRAKTWVK 318

Query: 99  QIIRVKRYEKVPVILVGNKVDLESEREVSSNEGRALAEEWGCPFMETSAKSKTMVDEL 156
           ++ R +    + + L GNK DL ++R V   E +A AEE    FMETSAK+   V+++
Sbjct: 319 ELQR-QASPNIVIALAGNKADLANKRMVEFEEAQAYAEENSLLFMETSAKTAMNVNDI 489
>14456
          Length = 1867

 Score = 70.9 bits (172), Expect = 3e-13,   Method: Compositional matrix adjust.
 Identities = 45/152 (29%), Positives = 84/152 (55%), Gaps = 5/152 (3%)
 Frame = -1

Query: 18   ALTVQFVTGTFIEKYDPTIE-DFYRKEIEVDSSPSVLEILDTAGTEQFASMRDLYIKNGQ 76
            +L  +FV+  F  +   TI  +F  K++ VD     ++I DTAG E+F S+R  + +   
Sbjct: 1096 SLMNRFVSNKFDAQSFHTIGVEFLNKDVVVDDETYTMQIWDTAGQERFKSLRTPFYRGAD 917

Query: 77   GFILVYSLVNQQSFQDIKPMRDQIIR---VKRYEKVPVILVGNKVDLESEREVSSNEGRA 133
              +L +S+ + QSF+++   R + +    ++     P +++GNK+D+E  R+V++ E R+
Sbjct: 916  CCLLTFSVDSMQSFRNLSMWRKEFLYYADIQDGVTFPFVVLGNKIDVEG-RQVTNEEARS 740

Query: 134  L-AEEWGCPFMETSAKSKTMVDELFAEIVRQM 164
                    P+ ETSAK  T V++ F   V+++
Sbjct: 739  WCTANSNAPYFETSAKDATNVEKAFLAAVQRL 644
>11257
          Length = 1102

 Score = 70.1 bits (170), Expect = 5e-13,   Method: Compositional matrix adjust.
 Identities = 40/128 (31%), Positives = 68/128 (53%), Gaps = 4/128 (3%)
 Frame = -2

Query: 41   RKEIEVDSSPSVLEILDTAGTEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQI 100
             K++ VD     ++I DTAG E++ S+R  + +     +L +S+ N +S Q +    D+ 
Sbjct: 1056 HKDVVVDGETFTMQIWDTAGQERYKSLRTPFYRGTDCCLLTFSVDNLKSLQSLSDWYDEF 877

Query: 101  IR---VKRYEKVPVILVGNKVDLESEREVSSNEGRALAEEWG-CPFMETSAKSKTMVDEL 156
            +    ++     P +++GNK D+E EREVSS +        G  P+ ETSAK    V + 
Sbjct: 876  VNYADIQDSASFPFVIIGNKADIE-EREVSSEDAYNWCRTHGNLPYFETSAKDSLNVQQA 700

Query: 157  FAEIVRQM 164
            F  +VR++
Sbjct: 699  FLAVVRRL 676
>32723
          Length = 384

 Score = 68.9 bits (167), Expect = 1e-12,   Method: Compositional matrix adjust.
 Identities = 39/108 (36%), Positives = 61/108 (56%)
 Frame = +2

Query: 62  EQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIIRVKRYEKVPVILVGNKVDLE 121
           E+F S+   Y ++    ILVY + +QQS++ + P     I +    KV   LVGNK+D  
Sbjct: 5   ERFRSITQSYYRSANALILVYDVCSQQSYESL-PQWIHEIELYAGTKVLAFLVGNKIDQT 181

Query: 122 SEREVSSNEGRALAEEWGCPFMETSAKSKTMVDELFAEIVRQMNYAAQ 169
            +RE+ ++ G+  AE +   F+ETSAK    V++LF+ I  Q+   AQ
Sbjct: 182 DKREIPTHIGKEFAERYEMRFLETSAKEADNVEKLFSTIAYQLTAQAQ 325
>01398
          Length = 1421

 Score = 67.4 bits (163), Expect = 3e-12,   Method: Compositional matrix adjust.
 Identities = 34/101 (33%), Positives = 59/101 (58%)
 Frame = -2

Query: 62   EQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIIRVKRYEKVPVILVGNKVDLE 121
            E+F S+   Y +N  G I+VY +  + +F+++K   ++        K   +++G+K D E
Sbjct: 1417 ERFRSITRSYYRNSVGVIIVYDITKRSTFENLKQWYEEARNHIEPHKAIFLVLGHKSDRE 1238

Query: 122  SEREVSSNEGRALAEEWGCPFMETSAKSKTMVDELFAEIVR 162
              R+V++ EGR  AE  G  F ETSAKS   ++++FA+I +
Sbjct: 1237 DARQVTAREGRRFAEMHGLKFFETSAKSGHNIEDVFAQIAK 1115
>11728
          Length = 635

 Score = 67.4 bits (163), Expect = 3e-12,   Method: Compositional matrix adjust.
 Identities = 45/149 (30%), Positives = 74/149 (49%), Gaps = 20/149 (13%)
 Frame = -1

Query: 19  LTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAGTEQFASMRDLYIKNGQGF 78
           L + + T  F  +Y PT+ D Y   + VDS P  L + DTAG E +  +R L       F
Sbjct: 443 LLISYTTNAFPGEYIPTVFDNYSANVMVDSKPINLGLWDTAGQEDYDRLRPLSYPQTDVF 264

Query: 79  ILVYSLVNQQSFQDIKPMRDQIIRVKRYEKV-------PVILVGNKVDLESERE------ 125
           ++ +SL++  SF+++K         K Y +V       P+ILVG K+DL  ++E      
Sbjct: 263 LICFSLISPASFENVK--------AKWYPEVSHHCPNTPIILVGTKLDLREDKETIEKLK 108

Query: 126 ------VSSNEGRALAEEWGC-PFMETSA 147
                 ++  +G A+A++ G   ++E SA
Sbjct: 107 EKKLAPITYPQGLAMAKDIGAGKYLECSA 21
>07465
          Length = 1103

 Score = 65.5 bits (158), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 41/141 (29%), Positives = 73/141 (51%), Gaps = 1/141 (0%)
 Frame = +3

Query: 18  ALTVQFVTGTFIEKYDPTIE-DFYRKEIEVDSSPSVLEILDTAGTEQFASMRDLYIKNGQ 76
           ++  ++  G F + Y  TI  DF  ++IEV      L + DTAG E+F ++   Y +  Q
Sbjct: 243 SMIQRYCKGIFTKDYKKTIGVDFLERQIEVGGEDVRLMLWDTAGQEEFDAITKAYYRGAQ 422

Query: 77  GFILVYSLVNQQSFQDIKPMRDQIIRVKRYEKVPVILVGNKVDLESEREVSSNEGRALAE 136
             +L +S V++ SF+ ++  + ++       ++ +++V NK+DL  +  V   E   LA+
Sbjct: 423 ACVLAFSTVDRDSFEALETWKRKV--EDEVGEIGMVIVQNKIDLIDDAVVRPEEAENLAK 596

Query: 137 EWGCPFMETSAKSKTMVDELF 157
           +    F  TS K    VDE+F
Sbjct: 597 KLRLRFYRTSVKENMNVDEVF 659
>13750
          Length = 503

 Score = 62.8 bits (151), Expect = 8e-11,   Method: Compositional matrix adjust.
 Identities = 42/137 (30%), Positives = 69/137 (50%), Gaps = 2/137 (1%)
 Frame = -2

Query: 26  GTFIEKYDPTIEDFYRKEIEVDSSPSVLE--ILDTAGTEQFASMRDLYIKNGQGFILVYS 83
           G F+++  PTI     +  E  + P  +   + DT G E + S+   + +  Q  +LVY 
Sbjct: 472 GFFMDRTMPTIAVLCSEFNESRTDPLNVRYTLWDTGGAETYRSLWVSHFRGAQVALLVYD 293

Query: 84  LVNQQSFQDIKPMRDQIIRVKRYEKVPVILVGNKVDLESEREVSSNEGRALAEEWGCPFM 143
           +  + SF     +  + + +K   +  VI VG+K DLE  R +S+  G+A A + G  F 
Sbjct: 292 VTCEWSFLTATTVWRKAL-MKNIPEAQVIFVGSKTDLEENRVISTERGQAFATQCGYTFF 116

Query: 144 ETSAKSKTMVDELFAEI 160
           ETS+ +   VD +F EI
Sbjct: 115 ETSSVTGKNVDAVFWEI 65
>33380
          Length = 282

 Score = 62.0 bits (149), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 29/72 (40%), Positives = 45/72 (62%)
 Frame = +3

Query: 53  LEILDTAGTEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIIRVKRYEKVPVI 112
           L+I DTAG E++ ++   Y +   GFIL+Y + N++SF  ++    Q I+   ++   V+
Sbjct: 66  LQIWDTAGQERYRTITTAYYRGAMGFILMYDVTNEESFNAVQDWCTQ-IKTYSWDNAQVV 242

Query: 113 LVGNKVDLESER 124
           LVGNK DLE ER
Sbjct: 243 LVGNKCDLEDER 278
>18509
          Length = 625

 Score = 59.3 bits (142), Expect = 9e-10,   Method: Compositional matrix adjust.
 Identities = 32/77 (41%), Positives = 51/77 (66%)
 Frame = -3

Query: 88  QSFQDIKPMRDQIIRVKRYEKVPVILVGNKVDLESEREVSSNEGRALAEEWGCPFMETSA 147
           Q F   +P++    RVK  ++VP++LVGNKVDL   R V   +G+ +AE +  P++ETSA
Sbjct: 590 QVF*RHQPVQRTD*RVKDADEVPMVLVGNKVDLPI-RNVEQRQGKHMAELYHIPYVETSA 414

Query: 148 KSKTMVDELFAEIVRQM 164
           K++  VD+ F  +VR++
Sbjct: 413 KTRQGVDDAFYTLVREI 363

 Score = 29.3 bits (64), Expect = 0.86,   Method: Compositional matrix adjust.
 Identities = 14/35 (40%), Positives = 22/35 (62%)
 Frame = -1

Query: 76  QGFILVYSLVNQQSFQDIKPMRDQIIRVKRYEKVP 110
           +GF+ V+++ N +SF+DI   R+QI   K   K P
Sbjct: 625 EGFLCVFAVNNLKSFEDINQYREQIKE*KMLMKSP 521
>31291
          Length = 446

 Score = 57.8 bits (138), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 45/140 (32%), Positives = 71/140 (50%), Gaps = 15/140 (10%)
 Frame = -1

Query: 53  LEILDTAGTEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIIRVKRYEKVPVI 112
           L++ DTAG E +  +R L   N   F+L +SL+++ S +++K      IR      VP++
Sbjct: 446 LQLWDTAGQEDYDRLRPLAYPNTDVFMLXFSLMSEASMKNVKVKWYPEIR-HHDPHVPIV 270

Query: 113 LVGNKVDLESERE------------VSSNEGRALAEEWGCP-FMETSAKSKTMVDELFAE 159
           LVG K+DL  ++E            VSSN+G  LA+      + E S+K++  +   F E
Sbjct: 269 LVGTKLDLRQDKEAVRKLRSSRQDPVSSNQGNDLAKAIKAKRYFECSSKTQENLKTAFEE 90

Query: 160 IVR-QMNYAAQPDK-DDPCC 177
            VR  +N   Q +K   P C
Sbjct: 89  TVRVALNMDGQNNKRPKPKC 30
>17511
          Length = 483

 Score = 57.8 bits (138), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 33/107 (30%), Positives = 56/107 (52%), Gaps = 4/107 (3%)
 Frame = -3

Query: 18  ALTVQFVTGTFIEKYDPTI-EDFYRKEIEVDSSPSVLEILDTAGTEQFASMRDLYIKNGQ 76
           +L  Q+V   F  +Y  TI  DF  KE+ VD     ++I DTAG E+F S+   + +   
Sbjct: 322 SLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQIWDTAGQERFQSLGVAFYRGAD 143

Query: 77  GFILVYSLVNQQSFQDIKPMRDQII---RVKRYEKVPVILVGNKVDL 120
             +LV+ +    +F+ +   RD+ +     +  E  P +++GNK+DL
Sbjct: 142 CCVLVFDVTMPNTFRSLDSWRDEFLIQASPRDPENFPFVVIGNKIDL 2
>01972
          Length = 2359

 Score = 55.1 bits (131), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 29/112 (25%), Positives = 63/112 (56%)
 Frame = +3

Query: 53  LEILDTAGTEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIIRVKRYEKVPVI 112
             + DTAG E+F  +RD Y   GQ  ++++ + ++ +++++      ++RV   E +P++
Sbjct: 453 FNVWDTAGQEKFGGLRDGYYIQGQCAVIMFDVTSRVTYKNVPNWHRDLVRV--CENIPIV 626

Query: 113 LVGNKVDLESEREVSSNEGRALAEEWGCPFMETSAKSKTMVDELFAEIVRQM 164
           L GNKVD++ +R+V + +      +    + + SAKS    ++ F  + R++
Sbjct: 627 LCGNKVDIK-DRKVKA-KAIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKL 776
>19006
          Length = 568

 Score = 54.3 bits (129), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 35/106 (33%), Positives = 54/106 (50%)
 Frame = -2

Query: 18  ALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAGTEQFASMRDLYIKNGQG 77
            L + F    F E Y PT+ + Y  +IEVDS    L + DTAG E +  +R L   +   
Sbjct: 393 CLLIVFSKDQFPEVYVPTVFENYVADIEVDSKQVELALWDTAGQEDYDRLRPLSYPDTDV 214

Query: 78  FILVYSLVNQQSFQDIKPMRDQIIRVKRYEKVPVILVGNKVDLESE 123
            ++ +S+ +  S ++I       +R      VP+ILVGNK DL ++
Sbjct: 213 ILMCFSIDSPDSLENIPEKWTPEVR-HFCPNVPIILVGNKKDLRND 79
>30760
          Length = 596

 Score = 53.9 bits (128), Expect = 4e-08,   Method: Compositional matrix adjust.
 Identities = 32/105 (30%), Positives = 50/105 (47%)
 Frame = -1

Query: 53  LEILDTAGTEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIIRVKRYEKVPVI 112
           L + D+AG E F+     +       ++VY + ++ SF       +++   K    +P +
Sbjct: 365 LYLFDSAGKEIFSENVTKFWDQPSVVMVVYDVTDETSFSGCVRWLERVRAAKPNTVIPGV 186

Query: 113 LVGNKVDLESEREVSSNEGRALAEEWGCPFMETSAKSKTMVDELF 157
           LV NK DL+  R VS  EG+ LA+  G  + E SAK     D  F
Sbjct: 185 LVANKTDLDERRRVSRKEGKDLAQSHGLEYFECSAKEMQNTDTPF 51
>26083
          Length = 432

 Score = 53.1 bits (126), Expect = 6e-08,   Method: Compositional matrix adjust.
 Identities = 33/101 (32%), Positives = 53/101 (52%), Gaps = 1/101 (0%)
 Frame = +1

Query: 18  ALTVQFVTGTFIEKYDPTIE-DFYRKEIEVDSSPSVLEILDTAGTEQFASMRDLYIKNGQ 76
           +L  +F+  +F   Y  TI  DF  K + ++     L++ DTAG E+F S+   YI++  
Sbjct: 121 SLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTIRLQLWDTAGQERFRSLIPSYIRDSS 300

Query: 77  GFILVYSLVNQQSFQDIKPMRDQIIRVKRYEKVPVILVGNK 117
             ++VY + N  SF       D  +R +R   V ++LVGNK
Sbjct: 301 VAVVVYDITNANSFHQTSKWIDD-VRTERGSDVIIMLVGNK 420
>34359
          Length = 1042

 Score = 53.1 bits (126), Expect = 7e-08,   Method: Compositional matrix adjust.
 Identities = 25/87 (28%), Positives = 54/87 (62%), Gaps = 2/87 (2%)
 Frame = +3

Query: 44  IEVDSSPSVLE--ILDTAGTEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQII 101
           ++ ++S  +L   + DTAG E+F  +RD Y   G   I+++ + ++ +++++      ++
Sbjct: 168 LQFNTSRGLLRFNVWDTAGQEKFGGLRDGYYIQGTCAIIMFDVTSRVTYKNVPNWHRDLV 347

Query: 102 RVKRYEKVPVILVGNKVDLESEREVSS 128
           RV   E +P++L GNKVD++ +R+V +
Sbjct: 348 RV--CENIPIVLCGNKVDIK-DRKVKA 419
>01095
          Length = 1745

 Score = 52.4 bits (124), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 30/85 (35%), Positives = 48/85 (56%)
 Frame = -1

Query: 80   LVYSLVNQQSFQDIKPMRDQIIRVKRYEKVPVILVGNKVDLESEREVSSNEGRALAEEWG 139
            +VY + NQ +F   K    ++ R +    + + L GNK DL ++R V   E +A AEE  
Sbjct: 1745 VVYDITNQDTFGRAKTWVKELQR-QASPNIVIALAGNKADLANKRMVEFEEAQAYAEENS 1569

Query: 140  CPFMETSAKSKTMVDELFAEIVRQM 164
              FMETSAK+   V+++F  I +++
Sbjct: 1568 LLFMETSAKTAMNVNDIFLAIAKKL 1494
>19656
          Length = 428

 Score = 51.6 bits (122), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 25/77 (32%), Positives = 40/77 (51%)
 Frame = +3

Query: 18  ALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAGTEQFASMRDLYIKNGQG 77
            L + + T  F  +Y PT+ D Y   + VD  P  L + DTAG E +  +R L       
Sbjct: 156 CLLISYTTNAFPGEYIPTVFDNYSANVMVDGRPVNLGLWDTAGQEDYDRLRPLSYPQTDV 335

Query: 78  FILVYSLVNQQSFQDIK 94
           F+L +S+ +  SF++I+
Sbjct: 336 FLLCFSVASPASFENIR 386
>29380
          Length = 853

 Score = 49.3 bits (116), Expect = 9e-07,   Method: Compositional matrix adjust.
 Identities = 29/90 (32%), Positives = 46/90 (51%), Gaps = 10/90 (11%)
 Frame = -2

Query: 101 IRVKRYEKVPVILVGNKVDLESE-REVSSNEGRALAEEWGCPFMETSAKSKTMVDELFAE 159
           +R +  E V +IL GNKVDL ++ R VS  + ++ A E G  F E SAK+   V+E+F  
Sbjct: 777 LRQQNTESVLIILAGNKVDLATQHRAVSFEDAQSFARENGLLFAEVSAKTGMAVNEIFMT 598

Query: 160 IVRQM---------NYAAQPDKDDPCCSAC 180
           +  Q+         N     ++++   S C
Sbjct: 597 LANQLIQQEIDGSRNRGVTLNRENGEASGC 508
>13745
          Length = 1045

 Score = 47.8 bits (112), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 32/109 (29%), Positives = 56/109 (51%), Gaps = 8/109 (7%)
 Frame = +2

Query: 62  EQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQII---RVKRYEKVPVILVGNKV 118
           E+F S+   + +     +LVY +    SF+++   RD+ +     +  E  P +++GNKV
Sbjct: 5   ERFQSLGVAFYRGADCCVLVYDVTAPNSFKNLDSWRDEFLIQASPRDPEHFPFVVLGNKV 184

Query: 119 DLESEREVSSNEGRALAEEW-----GCPFMETSAKSKTMVDELFAEIVR 162
           DL++ R+VS+      A++W       P+ ETSAK    V+  F  I +
Sbjct: 185 DLDN-RQVSTRR----AQQWCQSKNDIPYYETSAKEGINVEMAFQTIAK 316
>34597
          Length = 773

 Score = 46.2 bits (108), Expect = 7e-06,   Method: Compositional matrix adjust.
 Identities = 29/76 (38%), Positives = 44/76 (57%), Gaps = 1/76 (1%)
 Frame = -2

Query: 87  QQSFQDI-KPMRDQIIRVKRYEKVPVILVGNKVDLESEREVSSNEGRALAEEWGCPFMET 145
           ++SF++I K +R+  I     E V  +++GNK D+  +R VS   G A+A E    FMET
Sbjct: 715 KKSFENIVKWLRN--IDEHANEDVEKMILGNKCDMTDKRVVSKERGEAIAREHSIRFMET 542

Query: 146 SAKSKTMVDELFAEIV 161
           SAKS   ++  F E+ 
Sbjct: 541 SAKSNINIERAFCELA 494
>12339
          Length = 578

 Score = 46.2 bits (108), Expect = 7e-06,   Method: Compositional matrix adjust.
 Identities = 27/105 (25%), Positives = 55/105 (52%), Gaps = 4/105 (3%)
 Frame = -2

Query: 62  EQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIIR---VKRYEKVPVILVGNKV 118
           E+F S+   + +     ILVY +   ++F  +   + + +     +  E  P +++GNK+
Sbjct: 574 ERFQSLGVAFYRGADCCILVYDVTEXKTFDSLDSWQREFLNQASPRDPEHFPFVVIGNKI 395

Query: 119 DLESEREVSSNEGRAL-AEEWGCPFMETSAKSKTMVDELFAEIVR 162
           DL++ R V++  G+   + + G P+ ETSAK    V++ F  + +
Sbjct: 394 DLDN-RVVTAKRGQGWCSTKGGIPYFETSAKEAINVEQAFQTVAK 263
>31928
          Length = 429

 Score = 40.8 bits (94), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 27/87 (31%), Positives = 43/87 (49%), Gaps = 4/87 (4%)
 Frame = +2

Query: 35  TIEDFYRKEIEVDSS-PSVLEILDTAGTEQFASMRDL---YIKNGQGFILVYSLVNQQSF 90
           TIED Y   IE D      + I DT       +  DL   Y+    GF+LVY   + +SF
Sbjct: 53  TIEDIYTAVIETDRGVKEKVRIFDTGAAALETTEGDLPKHYLNFPDGFVLVYDTTSWESF 232

Query: 91  QDIKPMRDQIIRVKRYEKVPVILVGNK 117
           + +  ++  I + +   +V +I++GNK
Sbjct: 233 RRLDKLKKDIDKHRDKREVHMIVIGNK 313
>10708
          Length = 2775

 Score = 37.7 bits (86), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 27/67 (40%), Positives = 38/67 (56%), Gaps = 13/67 (19%)
 Frame = -3

Query: 109  VPVILVGNKVDLE----SERE--------VSSNEGRALAEEWGC-PFMETSAKSKTMVDE 155
            VP+ILVGNK DL     ++RE        V  +EGRA++E+     ++E SAK+K  V E
Sbjct: 2551 VPIILVGNKKDLRNDENTKRELMKMKQEPVRLDEGRAMSEKINAYSYLECSAKTKEGVRE 2372

Query: 156  LFAEIVR 162
            +F    R
Sbjct: 2371 VFETATR 2351
>09204
          Length = 1051

 Score = 36.6 bits (83), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 26/104 (25%), Positives = 53/104 (50%), Gaps = 5/104 (4%)
 Frame = -3

Query: 63   QFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIIRVKRYEK-VPVILVGNKVDLE 121
            ++ +M  +Y +  +  IL + L ++ SF  I   R  I  ++++E+   + + G K DL 
Sbjct: 1049 RYEAMSRIYYRGAKAAILCFDLTDKSSFDRI---RFWIGELRQHEEECKLYICGTKFDLV 879

Query: 122  SE----REVSSNEGRALAEEWGCPFMETSAKSKTMVDELFAEIV 161
             +    R V  +  +ALA++      ETS+ +   +++LF +I 
Sbjct: 878  HDDPERRAVPRSVAKALADDCMAEIYETSSMTGDNIEKLFTKIA 747
>31932
          Length = 437

 Score = 35.8 bits (81), Expect = 0.011,   Method: Compositional matrix adjust.
 Identities = 23/57 (40%), Positives = 32/57 (56%), Gaps = 1/57 (1%)
 Frame = -1

Query: 109 VPVILVGNKVDLESEREVSSNEGRALAEEWG-CPFMETSAKSKTMVDELFAEIVRQM 164
           VP +L+GNK DL   REV  +E   L +E     + ETS K  TM+DE    ++ +M
Sbjct: 401 VPCLLLGNKSDL-GHREVEQDEIEDLCKEHDFLGWSETSVKDGTMIDESMNYLIEEM 234
>18949
          Length = 414

 Score = 33.1 bits (74), Expect = 0.075,   Method: Compositional matrix adjust.
 Identities = 21/99 (21%), Positives = 39/99 (39%), Gaps = 2/99 (2%)
 Frame = +3

Query: 56  LDTAGTEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIIRVKRYEKVPVILVG 115
            D  G  Q   +   Y     G + +  + + +   + K   D ++R  +   +PV+++G
Sbjct: 72  FDLGGHRQARRVWKDYFPAVDGIVFIVDVHDTERITEAKAELDSLLRDDQIADIPVLVLG 251

Query: 116 NKVDLES--EREVSSNEGRALAEEWGCPFMETSAKSKTM 152
           NK+D     ER  S          W C  ++   K  T+
Sbjct: 252 NKMDKHGVVERRTSDT-------GWACTALQARTKRATV 347
>15662
          Length = 455

 Score = 26.6 bits (57), Expect = 6.4,   Method: Compositional matrix adjust.
 Identities = 10/49 (20%), Positives = 26/49 (53%)
 Frame = +2

Query: 71  YIKNGQGFILVYSLVNQQSFQDIKPMRDQIIRVKRYEKVPVILVGNKVD 119
           Y     G + +  + +++ F + K   D ++  ++    P++++GNK+D
Sbjct: 26  YFPAVDGIVFLVDVHDRERFVEAKAELDSLMTDEQVANAPILVLGNKID 172
>35581
          Length = 364

 Score = 26.2 bits (56), Expect = 9.0,   Method: Compositional matrix adjust.
 Identities = 10/40 (25%), Positives = 23/40 (57%)
 Frame = +2

Query: 53  LEILDTAGTEQFASMRDLYIKNGQGFILVYSLVNQQSFQD 92
           +++ DTAG E++ S+   Y ++ +  ++VY   ++    D
Sbjct: 200 VDLWDTAGQERYRSLTSSYYRDTKAVLIVYDAEHKLKLTD 319
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|27734998|ref|NP_775655.1| transmembrane protein 11
[Mus musculus]
         (190 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

09967                                                                 189   6e-49
27198                                                                  29   0.93 
13366                                                                  26   9.0  
>09967
          Length = 1454

 Score =  189 bits (480), Expect = 6e-49,   Method: Compositional matrix adjust.
 Identities = 90/163 (55%), Positives = 118/163 (72%), Gaps = 1/163 (0%)
 Frame = +2

Query: 26  DCYIVHEIYSGENAQDQFEYELEQALEAQYKYIVIEPTRIGDETARWITVGNCLHKTAVL 85
           DC ++ EIY  E++Q++FE EL++AL++    IVIEP+++GDE A+WI  GNCLHKTAVL
Sbjct: 2   DCIVIREIYEHESSQEEFEVELDRALDSGVNTIVIEPSKLGDEAAKWILFGNCLHKTAVL 181

Query: 86  AGTACLFTPLALPLDYSHY-ISLPAGVLSLACCTLYGISWQFDPCCKYQVEYDAYKLSRL 144
           +G +C+      P   SHY +SLP G LS+ C  +Y ISWQFDPCCKYQVE +  KL +L
Sbjct: 182 SGLSCVGVTGMWP---SHYEVSLPLGFLSVMCAGVYAISWQFDPCCKYQVETNMNKLPKL 352

Query: 145 PLHTLTSSTPVVLVRKDDLHRKRLHNTIALAALVYCVKKVYEL 187
           P+H+LTSSTPV LVRKDD  RK LHN ++L A   C  ++Y L
Sbjct: 353 PMHSLTSSTPVXLVRKDDSRRKILHNAVSLIAGGLCAYRLYHL 481
>27198
          Length = 1148

 Score = 29.3 bits (64), Expect = 0.93,   Method: Compositional matrix adjust.
 Identities = 17/54 (31%), Positives = 25/54 (46%)
 Frame = +2

Query: 133 QVEYDAYKLSRLPLHTLTSSTPVVLVRKDDLHRKRLHNTIALAALVYCVKKVYE 186
           Q+ +++Y   R PLH L  STP     KD L  KR     +    VY    +++
Sbjct: 8   QIMFESYGTKRGPLHGLLISTPYQT--KDQLQLKRFQAQSSGTTYVYDYPDIFK 163
>13366
          Length = 1953

 Score = 26.2 bits (56), Expect = 9.0,   Method: Compositional matrix adjust.
 Identities = 15/30 (50%), Positives = 18/30 (60%), Gaps = 4/30 (13%)
 Frame = +2

Query: 77  NCLHKTAVLAGTACLF----TPLALPLDYS 102
           NCLHK   +  +ACLF    +P  LPLD S
Sbjct: 767 NCLHKALAVQQSACLF*STGSP-TLPLDLS 853
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6681079|ref|NP_031824.1| cathepsin B preproprotein
[Mus musculus]
         (339 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

17495                                                                 190   6e-49
04499                                                                 138   3e-33
25422                                                                 134   4e-32
25989                                                                  91   5e-19
00131                                                                  81   8e-16
14999                                                                  78   5e-15
08974                                                                  77   1e-14
03747                                                                  56   2e-08
39186                                                                  55   5e-08
15855                                                                  53   1e-07
16373                                                                  53   2e-07
22371                                                                  49   2e-06
26028                                                                  49   3e-06
02978                                                                  47   1e-05
19751                                                                  47   2e-05
05910                                                                  45   5e-05
25728                                                                  44   1e-04
11639                                                                  43   2e-04
18223                                                                  39   0.003
13860                                                                  37   0.010
17355                                                                  31   0.68 
16037                                                                  31   0.68 
14768                                                                  29   3.1  
30755                                                                  28   7.3  
33110                                                                  28   7.7  
>17495
          Length = 643

 Score =  190 bits (483), Expect = 6e-49,   Method: Compositional matrix adjust.
 Identities = 96/181 (53%), Positives = 117/181 (64%), Gaps = 9/181 (4%)
 Frame = -3

Query: 19  DKPSFHPLSDDLINYINKQNTTWQAGRNF-YNVDISYLKKLCG--------TVLGGPKLP 69
           D P    LSD+ I  +  +  TWQAGRNF   V   +++ L G        T+    ++ 
Sbjct: 536 DDPQM--LSDEFIELVRNKAKTWQAGRNFDVTVSEHHIRALMGVHPDSHKFTLPEKREVL 363

Query: 70  GRVAFGEDIDLPETFDAREQWSNCPTIGQIRDQGSCGSCWAFGAVEAISDRTCIHTNGRV 129
           G     +  D+PE FDAR  W NCPTIG+IRDQGSCGSCWAFGAVEA+SDR CIH+N  V
Sbjct: 362 GNPLLADGGDIPEEFDARTAWPNCPTIGEIRDQGSCGSCWAFGAVEAMSDRVCIHSNATV 183

Query: 130 NVEVSAEDLLTCCGIQCGDGCNGGYPSGAWSFWTKKGLVSGGVYNSHVGCLPYTIPPCEH 189
           N   SA+DL++CC   CG GCNGG+P  AWS+WT KG+VSGG Y S  GC PY + PCEH
Sbjct: 182 NFHFSADDLVSCCHT-CGFGCNGGFPGAAWSYWTTKGIVSGGSYASKEGCRPYEVEPCEH 6

Query: 190 H 190
           H
Sbjct: 5   H 3
>04499
          Length = 2081

 Score =  138 bits (348), Expect = 3e-33,   Method: Compositional matrix adjust.
 Identities = 65/117 (55%), Positives = 87/117 (74%)
 Frame = +3

Query: 214 GYSPSYKEDKHFGYTSYSVSNSVKEIMAEIYKNGPVEGAFTVFSDFLTYKSGVYKHEAGD 273
           GY+ +Y+EDK +G   Y+V      + AE+  +GP E +F V+SDFL+Y+SGVYKH  GD
Sbjct: 3   GYNNTYQEDKIYGQDVYTVVGP-DCMQAELIAHGPFEVSFDVYSDFLSYESGVYKHVTGD 179

Query: 274 MMGGHAIRILGWGVENGVPYWLAANSWNLDWGDNGFFKILRGENHCGIESEIVAGIP 330
            +G HA++++GWG++ GVPYWL ANSWN DWGDNG+FKI+RG + C IE E VAG P
Sbjct: 180 YLGMHAVKMMGWGLQAGVPYWLVANSWNTDWGDNGYFKIMRGIDMCRIEEEPVAGTP 350
>25422
          Length = 532

 Score =  134 bits (338), Expect = 4e-32,   Method: Compositional matrix adjust.
 Identities = 75/180 (41%), Positives = 100/180 (55%), Gaps = 8/180 (4%)
 Frame = +2

Query: 45  RNFYNVDISYLKKLCGT------VLGGPKLPGRVAFGEDIDLPETFDAREQWSNCPTIGQ 98
           RNF+      +K+  G             LP +      + LP+ FD R +W+NCPT+ +
Sbjct: 2   RNFHQGRAGDVKRWLGVDIQASLSFAKKALPVKTFPETSVPLPDNFDPRTKWTNCPTLKE 181

Query: 99  IRDQGSCGSCWAFGAVEAISDRTCIHTNGRVNVEVSAEDLLTCCGIQCGDGCNGGYPSGA 158
           +RDQG+CGSCWAFGAVEA++DR CI +NG  +  +SAEDLL+CC   CG+GCNGGYP  A
Sbjct: 182 VRDQGNCGSCWAFGAVEAMTDRICILSNGTQHAHLSAEDLLSCCXT-CGNGCNGGYPGAA 358

Query: 159 WSFWTKKGLVSGGVYNSHV--GCLPYTIPPCEHHVNGSRPPCTGEGDTPRCNKSCEAGYS 216
           W F   K L S    ++ V                  +  PCTG+  TP C+K CEA Y+
Sbjct: 359 WEF--SKTLAS*PAXSTTVSRAASRTR*RRXTTTWWATSSPCTGDSKTPSCSKQCEASYA 532
>25989
          Length = 800

 Score = 91.3 bits (225), Expect = 5e-19,   Method: Compositional matrix adjust.
 Identities = 54/121 (44%), Positives = 69/121 (57%), Gaps = 2/121 (1%)
 Frame = -2

Query: 212 EAGYSPSYKEDKHFGYTSYSVSNSVKEIMAEIYKNGPVEGAFTVFSD--FLTYKSGVYKH 269
           EA Y+ +Y +DKH G +SYSV     E  +    +  V+      S   F +        
Sbjct: 799 EASYAKTYDKDKHNGKSSYSVEG---EETSRGNWSLTVQWRLPSLSTATFCSTSQVSTPT 629

Query: 270 EAGDMMGGHAIRILGWGVENGVPYWLAANSWNLDWGDNGFFKILRGENHCGIESEIVAGI 329
           + G   G    R +G+GVE G  YWL ANSWN DWGDNGFFKILRG + CGIES++VAG+
Sbjct: 628 QLGLNWGAMPSRSVGYGVEGGQKYWLVANSWNPDWGDNGFFKILRGVDECGIESQVVAGL 449

Query: 330 P 330
           P
Sbjct: 448 P 446
>00131
          Length = 1971

 Score = 80.9 bits (198), Expect = 8e-16,   Method: Compositional matrix adjust.
 Identities = 72/251 (28%), Positives = 109/251 (43%), Gaps = 6/251 (2%)
 Frame = +1

Query: 80  LPETFDAREQWSNCPTIGQIRDQGSCGSCWAFGAVEAISDRTCIHTNGRVNVEVSAEDLL 139
           LP   D R Q    P    ++DQGSCGS WAF A   +  +    T   +++  S + L+
Sbjct: 244 LPAFIDWRTQGYVTP----VKDQGSCGSGWAFSATGTLEGQHFRKTGDLLSL--SEQQLI 405

Query: 140 TCCGIQCGDGCNGGYPSGAWSFWTKK--GLVSGGVYNSHVGCLPYTIPPCEHHVNGSRPP 197
            C   Q  +GCNGG    A+ +   +  GL S   Y  ++G   Y    C    +  +  
Sbjct: 406 DCSVGQENNGCNGGLADNAYDYIMTQDNGLESEDDY-PYLGYFAY----CSTDPDKEQAK 570

Query: 198 CTGEGDTPRCNKSCEAGYSPSYKEDKHFGYTSYSVSNSVKEIMAEIYKNGPVEGAF-TVF 256
            TG  D    ++                    Y++ ++V  I       GPV        
Sbjct: 571 VTGCADVEPMDE--------------------YALMDAVAAI-------GPVAIVIDAAL 669

Query: 257 SDFLTYKSGVYKHEA-GDMMGGHAIRILGWG-VENGVPYWLAANSWNLDWGDNGFFKILR 314
             F +Y  GVY   +  +++ GHA+  +G+G + +G  YW+  NSW  DWG NG+  I R
Sbjct: 670 ETFQSYSEGVYNDPSCSEIIIGHAVLAVGYGTLMDGREYWIVKNSWGTDWGMNGYILIAR 849

Query: 315 GE-NHCGIESE 324
            + N CG+ SE
Sbjct: 850 NKGNMCGVASE 882
>14999
          Length = 796

 Score = 78.2 bits (191), Expect = 5e-15,   Method: Compositional matrix adjust.
 Identities = 38/96 (39%), Positives = 53/96 (55%), Gaps = 8/96 (8%)
 Frame = +2

Query: 243 IYKNGPVEGAFTVFSDFLTYKSGVYKHEAGD------MMGGHAIRILGWGVEN--GVPYW 294
           +Y+NGP+   F V SDF+ YKSG+Y H           +  HA+ ++G+G +   G  YW
Sbjct: 152 LYENGPLAVGFLVLSDFMQYKSGIYHHTGLTGPFNPFELTNHAVLVVGYGADKTTGEKYW 331

Query: 295 LAANSWNLDWGDNGFFKILRGENHCGIESEIVAGIP 330
           +  NSW   WG+ GFF+I R  + CG ES  V   P
Sbjct: 332 ITKNSWGEGWGEKGFFRIRRDNDECGFESMAVQSTP 439
>08974
          Length = 1670

 Score = 77.0 bits (188), Expect = 1e-14,   Method: Compositional matrix adjust.
 Identities = 66/240 (27%), Positives = 100/240 (41%), Gaps = 10/240 (4%)
 Frame = -1

Query: 80   LPETFDAREQWSNCPTIGQIRDQGSCGSCWAFGAVEAISDRTCIHTNGRVNVEVSAEDLL 139
            LP T D    W     + ++++QG CGSCWAF    ++  +    +   V++  S + L+
Sbjct: 1208 LPATVD----WRTKGYVTEVKNQGECGSCWAFSTTGSVEGQHFKESGNLVSL--SEQQLV 1047

Query: 140  TCCGIQCGDGCNGGYPSGAWSFW--TKKGLVSGGVYNSHVGCLPYTIPP--CEHHVNGSR 195
             C       GCNGGY   A+ +   T  GL+    Y       PY      C        
Sbjct: 1046 DCSKSGGNQGCNGGYMDQAFEYIMNTPGGLMXEADY-------PYLAIDGVCTAVSQKGV 888

Query: 196  PPCTGEGDTPRCNKSCEAGYSPSYKEDKHFGYTSYSVSNSVKEIMAEIYKNGPVEGAFTV 255
             P +G  D P                          V +S++   A++   GP+  A   
Sbjct: 887  APISGCVDIPS------------------------GVEDSLQGAAAQV---GPISVAIDA 789

Query: 256  FS-DFLTYKSGVY-----KHEAGDMMGGHAIRILGWGVENGVPYWLAANSWNLDWGDNGF 309
             S  F++Y  GVY     ++ AGD+   H + ++G+G   G  YWL  NSW+ DWG NG+
Sbjct: 788  SSLSFMSYSGGVYNDPYCRNTAGDL--NHGVLVVGYGTYQGTDYWLVKNSWSTDWGMNGY 615
>03747
          Length = 1915

 Score = 56.2 bits (134), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 32/94 (34%), Positives = 46/94 (48%), Gaps = 3/94 (3%)
 Frame = +3

Query: 233 SNSVKEIMAEIYKNGPVEGAFTV-FSDFLTYKSGVYKH-EAGDMMGGHAIRILGWGVENG 290
           ++S  ++   +   GPV  A       F  Y  GVY   E       H +  +G+G E+G
Sbjct: 141 ADSETDLRDALASVGPVSVAIDASHQSFQMYDGGVYDEPECSSTQLDHGVLAVGYGSEDG 320

Query: 291 VPYWLAANSWNLDWGDNGFFKILRGE-NHCGIES 323
             +WL  NSW L WG+ G+ K+ R + N CGI S
Sbjct: 321 KEFWLVKNSWGLSWGEKGYIKMSRDKSNQCGIAS 422
>39186
          Length = 728

 Score = 55.1 bits (131), Expect = 5e-08,   Method: Compositional matrix adjust.
 Identities = 32/90 (35%), Positives = 48/90 (53%), Gaps = 4/90 (4%)
 Frame = -1

Query: 239 IMAEIYKNGPVEGAF-TVFSDFLTYKSGVYKHEA-GDMMGGHAIRILGWG-VENGVPYWL 295
           +M  +   GPV          F +Y  GVY   +  +++ GHA+  +G+G + +G  YW+
Sbjct: 707 LMDAVAAIGPVAIVIDAALETFQSYSEGVYNDPSCSEIIIGHAVLAVGYGTLMDGREYWI 528

Query: 296 AANSWNLDWGDNGFFKILRGE-NHCGIESE 324
             NSW  DWG NG+  I R + N CG+ SE
Sbjct: 527 VKNSWGTDWGMNGYILIARNKGNMCGVASE 438
>15855
          Length = 2959

 Score = 53.1 bits (126), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 54/203 (26%), Positives = 82/203 (40%), Gaps = 4/203 (1%)
 Frame = -3

Query: 131  VEVSAEDLLTCCGIQCGDGCNGGYPSGAWSFWTKKGLVSGGVYNSHVGCLPYTIPPCEHH 190
            V +S ++L+ C  +    GCNGG PS A+    K G +      S+ G        C  H
Sbjct: 2870 VSLSEQELVDCDSLD--QGCNGGLPSNAYEAIMKLGGLESETAYSYKG----NDEKC--H 2715

Query: 191  VNGSRPPCTGEGDTPRCNKSCEAGYSPSYKEDKHFGYTSYSVSNSVKEIMAEIYKNGPVE 250
             N S+      G           G + S  ED               E+ A + +NGP+ 
Sbjct: 2714 FNRSKVAVKING-----------GLNISSNED---------------EMKAWLAQNGPIS 2613

Query: 251  GAFTVFSDFLTYKSGV---YKHEAGDMMGGHAIRILGWGVEN-GVPYWLAANSWNLDWGD 306
                 F+    Y  G+   +K         H + I+G+ V + G PYW+  NSW  DWG+
Sbjct: 2612 IGINAFA-MQFYFGGISHPWKIFCNPDKLDHGVLIVGYDVSSKGEPYWIIKNSWGPDWGE 2436

Query: 307  NGFFKILRGENHCGIESEIVAGI 329
             G++ + RG   CG+     + I
Sbjct: 2435 KGYYLVYRGSGVCGLNQMCTSAI 2367
>16373
          Length = 996

 Score = 53.1 bits (126), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 32/93 (34%), Positives = 44/93 (47%), Gaps = 2/93 (2%)
 Frame = -2

Query: 233 SNSVKEIMAEIYKNGPVE-GAFTVFSDFLTYKSGVYKHEAGDMMGGHAIRILGWGVENGV 291
           S S   +   +   GPV  G       FL+Y SGVY   +      HA+ ++G+G     
Sbjct: 737 SGSEAALQQALATVGPVSVGIDADHHSFLSYSSGVYYQPSCYHDINHAVLVVGYGTFQSQ 558

Query: 292 PYWLAANSWNLDWGDNGFFKILRG-ENHCGIES 323
            YWL  NSW +DWG  G+  + R  +N C I S
Sbjct: 557 QYWLVKNSWGVDWGMXGYIMMARNRDNMCSIAS 459
>22371
          Length = 435

 Score = 49.3 bits (116), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 27/89 (30%), Positives = 48/89 (53%)
 Frame = +2

Query: 237 KEIMAEIYKNGPVEGAFTVFSDFLTYKSGVYKHEAGDMMGGHAIRILGWGVENGVPYWLA 296
           ++I++ +   GPV  A    + +  Y  G+ +    + +  HA+ I+G+ +   VPY++ 
Sbjct: 14  EQILSLLGSVGPVSAAVDA-TTWHNYVGGIIQFHCENTIN-HAVDIVGYDLTGPVPYYIV 187

Query: 297 ANSWNLDWGDNGFFKILRGENHCGIESEI 325
            NSW  D+G +G+  I  G N CGI  E+
Sbjct: 188 RNSWGTDFGMDGYMYIKVGSNLCGIAEEV 274
>26028
          Length = 414

 Score = 48.9 bits (115), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 18/58 (31%), Positives = 34/58 (58%), Gaps = 6/58 (10%)
 Frame = -3

Query: 278 HAIRILGWGVEN------GVPYWLAANSWNLDWGDNGFFKILRGENHCGIESEIVAGI 329
           H + ++G+GV +       +PYW+  NSW   WG+ G++++ RG+N CG+     + +
Sbjct: 223 HGVLVVGYGVSDYPNFHKTLPYWIVKNSWGPRWGEQGYYRVYRGDNTCGVSEMATSAV 50
>02978
          Length = 2175

 Score = 47.0 bits (110), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 18/46 (39%), Positives = 31/46 (67%)
 Frame = +3

Query: 278 HAIRILGWGVENGVPYWLAANSWNLDWGDNGFFKILRGENHCGIES 323
           HA+  +G+GV  G  YWL  NSW+  WG++G+  + + +N+CG+ +
Sbjct: 231 HAVLAVGYGVMKGQAYWLVKNSWSTYWGNDGYVLMSQKDNNCGVAT 368
>19751
          Length = 564

 Score = 46.6 bits (109), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 26/81 (32%), Positives = 37/81 (45%)
 Frame = -1

Query: 79  DLPETFDAREQWSNCPTIGQIRDQGSCGSCWAFGAVEAISDRTCIHTNGRVNVEVSAEDL 138
           +LP+ FD    W     +  +++QG CGSCWAF     I     + T     +E S ++L
Sbjct: 255 ELPKEFD----WRQKHAVTHVKNQGQCGSCWAFSVTGNIEGLYAVKTGDL--MEFSEQEL 94

Query: 139 LTCCGIQCGDGCNGGYPSGAW 159
           L C        CNGG    A+
Sbjct: 93  LDCDSTDS--ACNGGLMDNAY 37
>05910
          Length = 1151

 Score = 44.7 bits (104), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 26/71 (36%), Positives = 35/71 (49%), Gaps = 2/71 (2%)
 Frame = +2

Query: 256 FSDFLTYKSGVYKHE-AGDMMGGHAIRILGWGVENGVPYWLAANSWNLDWGDNGF-FKIL 313
           F  F  Y+ GVY      +    HA+ ++G+G   G  YWL  NSWN  WG NG+     
Sbjct: 29  FYSFDFYRGGVYNEPYCSNTTMDHAVLLVGYGTYQGTDYWLIKNSWNTAWGINGYMMMQR 208

Query: 314 RGENHCGIESE 324
              N CGI ++
Sbjct: 209 NNNNMCGIATQ 241
>25728
          Length = 428

 Score = 43.9 bits (102), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 20/61 (32%), Positives = 33/61 (54%)
 Frame = +1

Query: 259 FLTYKSGVYKHEAGDMMGGHAIRILGWGVENGVPYWLAANSWNLDWGDNGFFKILRGENH 318
           F  Y  GV  +  G+ +  H +  +G+G ENG  Y +  NSW   WGD+G+ ++ + + H
Sbjct: 193 FQFYSHGVLSNGCGEALD-HGVLAVGYGSENGTNYTIVKNSWGAGWGDSGYIRLNQDKKH 369

Query: 319 C 319
            
Sbjct: 370 L 372
>11639
          Length = 976

 Score = 42.7 bits (99), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 44/171 (25%), Positives = 69/171 (40%), Gaps = 6/171 (3%)
 Frame = +1

Query: 105 CGSCWAFGAVEAISDRTCIHTNGR-VNVEVSAEDLLTCCGIQCGDGCNGGYPSGAWSFWT 163
           CGSCWA G+  +++DR  I   G   +  +S +D++  CG+     C GG   G +++ +
Sbjct: 463 CGSCWAMGSTSSLADRINIKRKGAWPSAYLSVQDIID-CGL--AGSCEGGDDVGVYAYAS 633

Query: 164 KKGLVSGGVYNSHVGCLPYTIPPCEHHVNGSRPPCTGEGDTPRCNKSCEAGYSPSYKEDK 223
            +G+           C  Y     E         CT E             YS +     
Sbjct: 634 TQGI-------PDETCNNYQAIDQECSTFNRCGSCTPEN-----------CYSVN----- 744

Query: 224 HFGYTSYSVSN-----SVKEIMAEIYKNGPVEGAFTVFSDFLTYKSGVYKH 269
              YT++ VS+        ++MAEIY+NGP+         F  Y  G+Y  
Sbjct: 745 --NYTTWKVSDYGPVSGRLQMMAEIYQNGPISCGVQATETFENYAGGIYSE 891
>18223
          Length = 475

 Score = 38.9 bits (89), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 32/105 (30%), Positives = 47/105 (44%), Gaps = 5/105 (4%)
 Frame = +1

Query: 232 VSNSVKEIMAEIYKNGPVEGAFTVFS-DFLTYKSGV-YKHEAGDMMGGHAIRILGWGV-- 287
           V  S   + A +   GP+  A    S  F  Y+SGV Y          H + ++G+    
Sbjct: 142 VPGSEAALEAAVADVGPIAVAIDASSGKFHFYRSGVFYDPCCSSTKLDHGVLVVGYAYSH 321

Query: 288 ENGVPYWLAANSWNLDWGDNGFFKILRG-ENHCGIESEIVAGIPR 331
           E    YW+  NSW   WG  G+  + R  +N+CGI S  +A  P+
Sbjct: 322 EYKQDYWIVKNSWGKKWGMEGYILMARNRQNNCGIAS--MASYPK 450
>13860
          Length = 470

 Score = 37.0 bits (84), Expect = 0.010,   Method: Compositional matrix adjust.
 Identities = 14/45 (31%), Positives = 25/45 (55%)
 Frame = +1

Query: 76  EDIDLPETFDAREQWSNCPTIGQIRDQGSCGSCWAFGAVEAISDR 120
           E++  P++ D    W N   +  +++QG CGSCW F +  ++  R
Sbjct: 319 ENVTAPKSVD----WRNEGAVTHVKNQGQCGSCWTFSSTGSLEGR 441
>17355
          Length = 1056

 Score = 31.2 bits (69), Expect = 0.68,   Method: Compositional matrix adjust.
 Identities = 16/64 (25%), Positives = 29/64 (45%)
 Frame = -3

Query: 239 IMAEIYKNGPVEGAFTVFSDFLTYKSGVYKHEAGDMMGGHAIRILGWGVENGVPYWLAAN 298
           + +++    PV   F  F++       + +    DM  G  IRIL  G EN   YW  ++
Sbjct: 958 VQSQMGNTDPVRNVFNPFTNKQ-----IGRRTGRDMTAGKNIRILDGGFENFDDYWSESD 794

Query: 299 SWNL 302
           + ++
Sbjct: 793 ADSI 782
>16037
          Length = 467

 Score = 31.2 bits (69), Expect = 0.68,   Method: Compositional matrix adjust.
 Identities = 14/27 (51%), Positives = 18/27 (66%), Gaps = 1/27 (3%)
 Frame = +3

Query: 299 SWNLDWGDNGFFKILRGENH-CGIESE 324
           SW  DWG NG+  +LR  N+ CGI S+
Sbjct: 3   SWGTDWGLNGYIMMLRNSNNMCGIASQ 83
>14768
          Length = 697

 Score = 28.9 bits (63), Expect = 3.1,   Method: Compositional matrix adjust.
 Identities = 12/42 (28%), Positives = 18/42 (42%)
 Frame = -2

Query: 52  ISYLKKLCGTVLGGPKLPGRVAFGEDIDLPETFDAREQWSNC 93
           +  + K    V+   +  G+V FGE I      D   QW+ C
Sbjct: 693 VHIMSKSSADVISASRRKGKVVFGEPIAASLGTDGTHQWNRC 568
>30755
          Length = 1137

 Score = 27.7 bits (60), Expect = 7.3,   Method: Compositional matrix adjust.
 Identities = 12/28 (42%), Positives = 14/28 (50%)
 Frame = -2

Query: 196 PPCTGEGDTPRCNKSCEAGYSPSYKEDK 223
           PPCT     P C+  C A  SP+   DK
Sbjct: 182 PPCTARNRLPLCDHLCPAKDSPASSHDK 99
>33110
          Length = 879

 Score = 27.7 bits (60), Expect = 7.7,   Method: Compositional matrix adjust.
 Identities = 14/49 (28%), Positives = 24/49 (48%)
 Frame = -1

Query: 257 SDFLTYKSGVYKHEAGDMMGGHAIRILGWGVENGVPYWLAANSWNLDWG 305
           S     K GVY +E+G  +G   + +     E G P W+  N++++  G
Sbjct: 198 STVKIRKLGVY*NESGK*LGRRLLSLCERAQETGQPQWVVRNAFHVLQG 52
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|56605979|ref|NP_663430.2| basic transcription factor
3 [Mus musculus]
         (204 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

05631                                                                 189   7e-49
08594                                                                  57   4e-09
24263                                                                  37   0.004
23102                                                                  34   0.045
24842                                                                  28   2.3  
03977                                                                  27   5.1  
25799                                                                  26   9.4  
>05631
          Length = 1440

 Score =  189 bits (480), Expect = 7e-49,   Method: Compositional matrix adjust.
 Identities = 102/157 (64%), Positives = 112/157 (71%), Gaps = 4/157 (2%)
 Frame = -2

Query: 48  MNQEKLAKLQA---QVRIGGKGTARRKKKVVHRTATADDKKLQFSLKKLGVNNISGIEEV 104
           MN EKL +LQA   QVRIGGKG+ARRKKKV+HRTAT DDKKLQ SLKKL VN I GIEEV
Sbjct: 818 MNPEKLKQLQAKADQVRIGGKGSARRKKKVIHRTATTDDKKLQSSLKKLSVNTIPGIEEV 639

Query: 105 NMFTNQGTVIHFNNPKVQASLAANTFTITGHAETKQLTEMLPSILNQLGADSLTSLRRLA 164
           NM    G VIHFNNPKVQASLAANTF +TGHAE KQ+ EMLP ILNQLG +SL+SLR+LA
Sbjct: 638 NMIKEDGQVIHFNNPKVQASLAANTFAVTGHAEIKQIAEMLPGILNQLGTESLSSLRKLA 459

Query: 165 EALPKQSVD-GKAPLATGXXXXXXXXXXXXNFDEASK 200
             +   + D  K   A              NFDEASK
Sbjct: 458 STVANAAGDVAKQNAADEDDDDDDVPELVGNFDEASK 348
>08594
          Length = 360

 Score = 57.4 bits (137), Expect = 4e-09,   Method: Compositional matrix adjust.
 Identities = 35/62 (56%), Positives = 41/62 (66%), Gaps = 6/62 (9%)
 Frame = -1

Query: 29  PSLPLGGSRGRESQMKETIM---NQEKLAKLQA---QVRIGGKGTARRKKKVVHRTATAD 82
           PS P GG+          I+    +EKL +LQA   QVRIGGKG+ARRKKKV+HRTAT D
Sbjct: 189 PSEPAGGA----------ILPRIEEEKLKQLQAKADQVRIGGKGSARRKKKVIHRTATTD 40

Query: 83  DK 84
           DK
Sbjct: 39  DK 34
>24263
          Length = 1042

 Score = 37.4 bits (85), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 16/61 (26%), Positives = 35/61 (57%)
 Frame = +2

Query: 83  DKKLQFSLKKLGVNNISGIEEVNMFTNQGTVIHFNNPKVQASLAANTFTITGHAETKQLT 142
           +KK + ++ KLG+  ++G+  V +  ++  +   N P V  S A++T+ + G A+ + L 
Sbjct: 260 EKKARKAMSKLGLKAVTGVTRVTIRKSKNILFVINRPDVYKSPASDTYIVFGEAKIEDLN 439

Query: 143 E 143
           +
Sbjct: 440 Q 442
>23102
          Length = 477

 Score = 33.9 bits (76), Expect = 0.045,   Method: Compositional matrix adjust.
 Identities = 16/61 (26%), Positives = 34/61 (55%)
 Frame = -1

Query: 83  DKKLQFSLKKLGVNNISGIEEVNMFTNQGTVIHFNNPKVQASLAANTFTITGHAETKQLT 142
           +KK +  + KLG+  I G+  V +  ++  +   NNP V  +  ++T+ + G A+ + L+
Sbjct: 303 EKKARKIMLKLGLKQIQGVNRVTIRKSKNILFVINNPDVYKNPHSDTYIVFGEAKIEDLS 124

Query: 143 E 143
           +
Sbjct: 123 Q 121
>24842
          Length = 1096

 Score = 28.1 bits (61), Expect = 2.3,   Method: Compositional matrix adjust.
 Identities = 16/50 (32%), Positives = 28/50 (56%), Gaps = 2/50 (4%)
 Frame = +1

Query: 127 ANTFTITGHAETKQLTEMLPSILNQLGADSLTSLRRLA--EALPKQSVDG 174
            NTF + G      L+ +L ++++Q    SLTS+ +L   + + K S+DG
Sbjct: 298 VNTFPVIGTVGRFVLSTVLVTLIHQYLGGSLTSVNKLNI*KVIVKHSMDG 447
>03977
          Length = 603

 Score = 26.9 bits (58), Expect = 5.1,   Method: Compositional matrix adjust.
 Identities = 15/51 (29%), Positives = 22/51 (43%), Gaps = 7/51 (13%)
 Frame = +2

Query: 94  GVNNISGIEEVNMFTNQGTVIHF-------NNPKVQASLAANTFTITGHAE 137
           G + I  ++    ++++GT  HF       NNP  Q S   N     GHA 
Sbjct: 188 GFDGIVFVDFPGFYSSKGTFSHFCKVRSVRNNPSKQKSKLGNVLKYLGHAR 340
>25799
          Length = 629

 Score = 26.2 bits (56), Expect = 9.4,   Method: Compositional matrix adjust.
 Identities = 11/21 (52%), Positives = 12/21 (57%)
 Frame = +1

Query: 22  WPGAEATPSLPLGGSRGRESQ 42
           WP A   PSLP GG  G  +Q
Sbjct: 175 WPSALCPPSLPAGGQCGTATQ 237
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|61657895|ref|NP_082053.1| peroxin1 [Mus musculus]
         (1244 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

03022                                                                 192   9e-49
07243                                                                 182   6e-46
02582                                                                 175   9e-44
01642                                                                 163   4e-40
19129                                                                 160   4e-39
07247                                                                 140   4e-38
23766                                                                 150   8e-38
12235                                                                 113   4e-25
25936                                                                 105   8e-23
20270                                                                  91   6e-22
38672                                                                  92   1e-18
00810                                                                  90   6e-18
25671                                                                  73   7e-13
26408                                                                  60   5e-09
17843                                                                  55   1e-07
02194                                                                  48   2e-05
06766                                                                  48   3e-05
14413                                                                  41   0.003
05247                                                                  30   0.005
19561                                                                  40   0.006
29846                                                                  39   0.010
15498                                                                  37   0.034
01279                                                                  37   0.053
08000                                                                  32   1.7  
>03022
          Length = 2255

 Score =  192 bits (487), Expect = 9e-49,   Method: Compositional matrix adjust.
 Identities = 108/257 (42%), Positives = 154/257 (59%), Gaps = 3/257 (1%)
 Frame = +2

Query: 768  LTLTTSDFQKALRGFLPASLRNVNLHKPRDLGWDKIGGLHEVRQILMDTIQLPAKYPELF 827
            + LT  DF  AL+   PA+ R      P    W+ +G L  VR  L D+I      PE+ 
Sbjct: 1331 VALTEEDFMGALKKAQPAAKREGFATVPTTT-WEDVGALSNVRAQLKDSILCRIHDPEVS 1507

Query: 828  ANLPIRQRTGILLYGPPGTGKTLLAGVVARESGMNFISIKGPELLSKYIGASEQAVRDVF 887
            +   +   +GI+L GPPG GKTL+A  +A E+G+NFI IKGPELL KY+G SE+ +R+ F
Sbjct: 1508 SAFGLPTNSGIILVGPPGCGKTLVAKAMANEAGLNFIYIKGPELLDKYVGESERNLREKF 1687

Query: 888  IRAQAAKPCILFFDEFESI-APRRGHDNTGVTDRVVNQLLTQLDGVEGLQGVYVLAATSR 946
             +AQA  PC++FFDE +++ + R+ +D + V   V NQLL  +DG      VYV+ AT+ 
Sbjct: 1688 DKAQACAPCLIFFDEMDTLCSNRQNNDGSNVGKSVTNQLLALMDGCGERSQVYVMGATNI 1867

Query: 947  PDLIDPALLRPGRLDKCVYCPPPDQVSRLEILTVLSK--SLALADDVDLQHVASVTDSFT 1004
             + +DPAL RPGR D+ ++   PD   RL+IL  L+K  S    +  D+Q +A  T+ F+
Sbjct: 1868 IENVDPALQRPGRFDRKIFIGLPDTDGRLDILRALTKGGSQRKLESCDMQQLAQDTEGFS 2047

Query: 1005 GADLKALLYNAQLEALQ 1021
            GADLK L+  A   AL+
Sbjct: 2048 GADLKHLVNEASTIALK 2098

 Score = 60.8 bits (146), Expect(2) = 8e-16,   Method: Compositional matrix adjust.
 Identities = 30/72 (41%), Positives = 45/72 (62%)
 Frame = +1

Query: 839 LLYGPPGTGKTLLAGVVARESGMNFISIKGPELLSKYIGASEQAVRDVFIRAQAAKPCIL 898
           LLYGP G+GK  LA  +A +  +  +  K   L+S   G SEQ VRD+F +A +  PC+L
Sbjct: 649 LLYGPRGSGKRFLAECIAGQLKLPLLKPKINTLISGVSGDSEQRVRDLFDQAVSQAPCVL 828

Query: 899 FFDEFESIAPRR 910
           + ++ E +APR+
Sbjct: 829 YLEDIECLAPRQ 864

 Score = 42.0 bits (97), Expect(2) = 8e-16,   Method: Compositional matrix adjust.
 Identities = 32/98 (32%), Positives = 55/98 (56%), Gaps = 2/98 (2%)
 Frame = +2

Query: 920  RVVNQLLTQLDGV-EGLQGVYVLAATSRPDLIDPALLRPGR-LDKCVYCPPPDQVSRLEI 977
            R+V++L + +D + E  + V V+A TSR + +   L  PGR ++K +    PD+ SR  +
Sbjct: 899  RIVSELGSCIDELQEKPENVVVVATTSRIEAVHRDLRIPGRFMEKALGM--PDEGSREGL 1072

Query: 978  LTVLSKSLALADDVDLQHVASVTDSFTGADLKALLYNA 1015
            L  L     L+  + L+ +A +T  F   DL+AL++ A
Sbjct: 1073 LQRLCSRYTLSPHLKLKTLARLTPGFVAGDLRALVHGA 1186

 Score = 35.8 bits (81), Expect = 0.10,   Method: Compositional matrix adjust.
 Identities = 44/200 (22%), Positives = 81/200 (40%)
 Frame = +2

Query: 553  NGALLITGGKGSGKSTFAKAICKEAQDTLDARVETVDCKALRGKRLESIQKALEVAFSEA 612
            N  +++ G  G GK+  AKA+  EA          +    L  K +   ++ L   F +A
Sbjct: 1529 NSGIILVGPPGCGKTLVAKAMANEA----GLNFIYIKGPELLDKYVGESERNLREKFDKA 1696

Query: 613  AWRQPSVIXXXXXXXIAGLPSVPEQEHSPEAVQSQRLAHALNDMIKEFVSTGSLVALIAT 672
                P +I       +       +  +  ++V +Q LA      + +     S V ++  
Sbjct: 1697 QACAPCLIFFDEMDTLCSNRQNNDGSNVGKSVTNQLLA------LMDGCGERSQVYVMGA 1858

Query: 673  SQLQQSLHPSLVSAQGIHTFQCVQHLQPPNPEQRCEILHSVVKNKLGCDISNFPDLDLQC 732
            + + +++ P+L   Q    F     +  P+ + R +IL ++ K   G         D+Q 
Sbjct: 1859 TNIIENVDPAL---QRPGRFDRKIFIGLPDTDGRLDILRALTK---GGSQRKLESCDMQQ 2020

Query: 733  IAKDTEAFVARDFTVLVDRA 752
            +A+DTE F   D   LV+ A
Sbjct: 2021 LAQDTEGFSGADLKHLVNEA 2080
>07243
          Length = 1112

 Score =  182 bits (463), Expect = 6e-46,   Method: Compositional matrix adjust.
 Identities = 100/258 (38%), Positives = 154/258 (59%), Gaps = 3/258 (1%)
 Frame = +1

Query: 768  LTLTTSDFQKALRGFLPASLRNVNLHKPRDLGWDKIGGLHEVRQILMDTIQLPAKYPELF 827
            L +TT    + L   +   + N++   P D+ +  IGGL E  + L + I+LP   PELF
Sbjct: 106  LDMTTLTIMRYLPREVDPLVYNMSHEDPGDVTYSAIGGLTEQIRELREVIELPLLNPELF 285

Query: 828  ANLPIRQRTGILLYGPPGTGKTLLAGVVARESGMNFISIKGPELLSKYIGASEQAVRDVF 887
              + I    G LLYGPPGTGKTLLA  VA +   NF+ +    ++ KYIG S + +R++F
Sbjct: 286  LRVGITPPKGCLLYGPPGTGKTLLARAVASQLDANFLKVVSSAIVDKYIGESARLIREMF 465

Query: 888  IRAQAAKPCILFFDEFESIAPRRGHDNTGV---TDRVVNQLLTQLDGVEGLQGVYVLAAT 944
              A+  +PCI+F DE ++I  RR  + T       R + +LL Q+DG + L  V ++ AT
Sbjct: 466  NYARDHQPCIIFMDEIDAIGGRRFSEGTSADREIQRTLMELLNQMDGFDSLGQVKMIMAT 645

Query: 945  SRPDLIDPALLRPGRLDKCVYCPPPDQVSRLEILTVLSKSLALADDVDLQHVASVTDSFT 1004
            +RPD +DPALLRPGRLD+ +  P P++ +RLEIL + +  +A   ++D + +  ++D+F 
Sbjct: 646  NRPDTLDPALLRPGRLDRKIEIPLPNEQARLEILKIHALIIAKHGEIDYEAIVKLSDNFN 825

Query: 1005 GADLKALLYNAQLEALQG 1022
            GADL+ +   A L A++ 
Sbjct: 826  GADLRNVCTEAGLFAIRA 879
>02582
          Length = 1101

 Score =  175 bits (444), Expect = 9e-44,   Method: Compositional matrix adjust.
 Identities = 103/287 (35%), Positives = 160/287 (55%), Gaps = 35/287 (12%)
 Frame = +3

Query: 770  LTTSDFQKALRGFLPASLRNVN-LHKPRDLGWDKIGGLHEVRQILMDTIQLPAKYPELFA 828
            +T +D + AL  F P+  R V+ +   R + W  IGGL  V+  +   ++ P  YP+ F 
Sbjct: 45   ITRADMEAALLTFKPSMQRGVDCIVDARSVPWTDIGGLDLVKLQIRQAVEWPLLYPDTFQ 224

Query: 829  NLPIRQRTGILLYGPPGTGKTLLAGVVARESGMNFISIKGPELLSKYIGASEQAVRDVFI 888
             L +    G+LLYGPPG GKT LA   A    + F+S+   +L S Y+G +E+ + + F 
Sbjct: 225  ALGLPLTKGVLLYGPPGCGKTTLAQAAATACHVTFLSLSCAQLYSPYVGDAEKKISETFQ 404

Query: 889  RAQAAKPCILFFDEFESIAPRRGHDN--TGVTDRVVNQLLTQLDG--------------- 931
            +A+A  P ILF DE ++I  +R   +  +GV++RV++ LL ++DG               
Sbjct: 405  KARALAPSILFLDEMDAIVGKRSDSSLGSGVSERVLSALLNEMDGIGVRLDDKSDSREME 584

Query: 932  VEGL-----------------QGVYVLAATSRPDLIDPALLRPGRLDKCVYCPPPDQVSR 974
            +EG                  + V V+AAT+RPD++DPALLRPGR+D+ +Y PPPD   R
Sbjct: 585  IEGSSDHTPQVRQHAVKEAHDRHVLVVAATNRPDMLDPALLRPGRMDRLIYVPPPDVQGR 764

Query: 975  LEILTVLSKSLALADDVDLQHVASVTDSFTGADLKALLYNAQLEALQ 1021
            L+  T+ ++ + L  DVD++ +A +T  +TGAD+K L     L AL+
Sbjct: 765  LQSFTIHTRKMPLGKDVDVKQLADLTAGYTGADIKTLCNEVGLLALK 905
>01642
          Length = 1406

 Score =  163 bits (412), Expect = 4e-40,   Method: Compositional matrix adjust.
 Identities = 83/225 (36%), Positives = 135/225 (60%), Gaps = 3/225 (1%)
 Frame = -1

Query: 800  WDKIGGLHEVRQILMDTIQLPAKYPELFANLPIRQRTGILLYGPPGTGKTLLAGVVARES 859
            +  IGG+   +Q + + ++LP  + EL+  + I    G+L+YGPPG GKT+LA  VA  +
Sbjct: 998  YSDIGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAKAVAHHT 819

Query: 860  GMNFISIKGPELLSKYIGASEQAVRDVFIRAQAAKPCILFFDEFESIAPRRGHDNTGV-- 917
               FI + G E + KY+G   + VRDVF  A+   P I+F DE ++IA +R    TG   
Sbjct: 818  TAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRFDAQTGADR 639

Query: 918  -TDRVVNQLLTQLDGVEGLQGVYVLAATSRPDLIDPALLRPGRLDKCVYCPPPDQVSRLE 976
               R++ +LL Q+DG +    V V+ AT+R D +DPALLRPGRLD+ +  P PD+  +  
Sbjct: 638  EVQRILLELLNQMDGFDQTVNVKVIMATNRADTLDPALLRPGRLDRKIEFPLPDRRQKRL 459

Query: 977  ILTVLSKSLALADDVDLQHVASVTDSFTGADLKALLYNAQLEALQ 1021
            I + ++  + ++++VDL+   +  D  +GAD+ A+   A ++A++
Sbjct: 458  IFSTITGKMNISEEVDLEDYVARPDKISGADINAICQEAGMQAVR 324
>19129
          Length = 1020

 Score =  160 bits (404), Expect = 4e-39,   Method: Compositional matrix adjust.
 Identities = 81/182 (44%), Positives = 116/182 (63%), Gaps = 3/182 (1%)
 Frame = +1

Query: 797 DLGWDKIGGLHEVRQILMDTIQLPAKYPELFANLPIRQRTGILLYGPPGTGKTLLAGVVA 856
           D  ++ +GGL +  + + + I+LP K+PELF  L I Q  G+LLYGPPGTGKTLLA  VA
Sbjct: 475 DSTYEMVGGLDKQIKEIKEVIELPVKHPELFEALGIAQPKGVLLYGPPGTGKTLLARAVA 654

Query: 857 RESGMNFISIKGPELLSKYIGASEQAVRDVFIRAQAAKPCILFFDEFESIAPRRGHDNTG 916
             +   FI + G EL+ K+IG   + VR++F+ A+   P I+F DE +SI   R    +G
Sbjct: 655 HHTECTFIRVSGSELVQKFIGEGSRMVRELFVMAREHAPSIIFMDEIDSIGSSRLEGGSG 834

Query: 917 ---VTDRVVNQLLTQLDGVEGLQGVYVLAATSRPDLIDPALLRPGRLDKCVYCPPPDQVS 973
                 R + +LL QLDG E  Q + V+ AT+R D++D ALLRPGR+D+ +  PPP++ +
Sbjct: 835 GDSEVQRTMLELLNQLDGFEPKQNIKVIMATNRIDILDSALLRPGRIDRKIEFPPPNEEA 1014

Query: 974 RL 975
           RL
Sbjct: 1015RL 1020
>07247
          Length = 1753

 Score =  140 bits (354), Expect(2) = 4e-38,   Method: Compositional matrix adjust.
 Identities = 71/182 (39%), Positives = 113/182 (62%), Gaps = 3/182 (1%)
 Frame = -2

Query: 844  PGTGKTLLAGVVARESGMNFISIKGPELLSKYIGASEQAVRDVFIRAQAAKPCILFFDEF 903
            PGTGKTLLA  VA +   NF+ +    ++ KYIG S + +R++F  A+  +PCI+F DE 
Sbjct: 1407 PGTGKTLLARAVASQLDCNFLKVVSSAIVDKYIGESARLIREMFAFARDHEPCIIFMDEI 1228

Query: 904  ESIAPRRGHDNTGV---TDRVVNQLLTQLDGVEGLQGVYVLAATSRPDLIDPALLRPGRL 960
            ++I  RR  + T       R + +LL Q+DG + L  V ++ AT+RPD +DPALLRPGRL
Sbjct: 1227 DAIGGRRFSEGTSADREIQRTLMELLNQMDGFDALGQVKMIMATNRPDTLDPALLRPGRL 1048

Query: 961  DKCVYCPPPDQVSRLEILTVLSKSLALADDVDLQHVASVTDSFTGADLKALLYNAQLEAL 1020
            D+ +    P++ +RLEIL + +  +A   ++D + V  +++ F GADL+ +   A + A+
Sbjct: 1047 DRKIEISLPNEQARLEILKIHANPIAKHGEIDWEAVVKLSEDFNGADLRNVCTEAGMFAI 868

Query: 1021 QG 1022
            + 
Sbjct: 867  RA 862

 Score = 37.4 bits (85), Expect(2) = 4e-38,   Method: Composition-based stats.
 Identities = 20/50 (40%), Positives = 30/50 (60%)
 Frame = -1

Query: 789  NVNLHKPRDLGWDKIGGLHEVRQILMDTIQLPAKYPELFANLPIRQRTGI 838
            N+++  P D+ +++IGGL E  + L + I+LP   PELF      QR GI
Sbjct: 1570 NMSVEDPGDITFNQIGGLGEQVRELREVIELPLLNPELF------QRVGI 1439
>23766
          Length = 1463

 Score =  150 bits (378), Expect(2) = 8e-38,   Method: Compositional matrix adjust.
 Identities = 76/190 (40%), Positives = 117/190 (61%), Gaps = 3/190 (1%)
 Frame = +1

Query: 837  GILLYGPPGTGKTLLAGVVARESGMNFISIKGPELLSKYIGASEQAVRDVFIRAQAAKPC 896
            G++LYGPPGTGKTLLA  VA ++   F+ + G EL+ KY+G   + VR++F  A+   P 
Sbjct: 160  GVILYGPPGTGKTLLAKAVANQTSATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPS 339

Query: 897  ILFFDEFESIAPRRGHDNTG---VTDRVVNQLLTQLDGVEGLQGVYVLAATSRPDLIDPA 953
            I+F DE +++  +R   N+G      R + +LL QLDG +    V V+ AT+R + +DPA
Sbjct: 340  IVFIDEIDAVGTKRYESNSGGEREIQRTMLELLNQLDGFDSRGDVKVIMATNRIETLDPA 519

Query: 954  LLRPGRLDKCVYCPPPDQVSRLEILTVLSKSLALADDVDLQHVASVTDSFTGADLKALLY 1013
            L+RPGR+D+ +  P PD+ ++  I T+ +  + LA DV++       D  +GAD+KA+  
Sbjct: 520  LIRPGRIDRKIEFPLPDEKTKRRIFTIHTSRMTLAGDVNIDDYVMSKDDLSGADIKAICT 699

Query: 1014 NAQLEALQGR 1023
             A L AL+ R
Sbjct: 700  EAGLLALRER 729

 Score = 26.9 bits (58), Expect(2) = 8e-38,   Method: Compositional matrix adjust.
 Identities = 14/52 (26%), Positives = 26/52 (50%), Gaps = 8/52 (15%)
 Frame = +2

Query: 799 GWDK--------IGGLHEVRQILMDTIQLPAKYPELFANLPIRQRTGILLYG 842
           GW+K        IGGL    Q + ++++LP  +PE +  + I+ +  +   G
Sbjct: 23  GWEKAPQETYADIGGLDTQIQEIKESVELPLTHPEYYEEMGIKHQKVLSCMG 178
>12235
          Length = 1749

 Score =  113 bits (283), Expect = 4e-25,   Method: Compositional matrix adjust.
 Identities = 64/167 (38%), Positives = 94/167 (56%), Gaps = 5/167 (2%)
 Frame = +1

Query: 858  ESGMNFISIKGPELLSKYIGASEQAVRDVFIRAQAAKPCILFFDEFESIAPRRGHDNTG- 916
            E+ + FI++ G E L  ++G     VRD+F  A+   PCILF DE +++  +R   N G 
Sbjct: 1    EANVPFITVSGSEFLEMFVGVGPSRVRDMFATARKNAPCILFVDEIDAVGRKRSGRNFGG 180

Query: 917  --VTDRVVNQLLTQLDGVEGLQGVYVLAATSRPDLIDPALLRPGRLDKCVYCPPPDQVSR 974
                +  +NQLL ++DG     GV VLAAT+R D++D ALLRPGR D+ ++ P PD   R
Sbjct: 181  QSEQENTLNQLLVEMDGFNTQTGVVVLAATNRVDILDAALLRPGRFDRQIFVPLPDIKXR 360

Query: 975  LEILTVLSKSLAL-ADDVDL-QHVASVTDSFTGADLKALLYNAQLEA 1019
              I  V    L    +  DL + +A++T  F+GAD+  +   A L A
Sbjct: 361  ASIFKVHLDPLKTEVNKNDLARKMAALTPGFSGADIANVCNEAALIA 501
>25936
          Length = 459

 Score =  105 bits (263), Expect = 8e-23,   Method: Compositional matrix adjust.
 Identities = 56/140 (40%), Positives = 77/140 (55%), Gaps = 1/140 (0%)
 Frame = +2

Query: 689 IHTFQCVQHLQPPNPEQRCEILHSVVK-NKLGCDISNFPDLDLQCIAKDTEAFVARDFTV 747
           +H  Q V  ++PP+   R EIL   +K +   C  S    LDL  +A  TE FVARD   
Sbjct: 2   LHFVQEVTTIKPPDKAGRQEILQCTLKSHSTVCARSTLERLDLDSVASRTEGFVARDIQT 181

Query: 748 LVDRAIXXXXXXXXXXXXEDLTLTTSDFQKALRGFLPASLRNVNLHKPRDLGWDKIGGLH 807
           LV+RA+              + L  +DF  AL GF P ++RNV+LH   +LGW  +GGL 
Sbjct: 182 LVNRALHARLAATPSAESNTVILQQTDFDTALEGFKPLAIRNVHLHTSGELGWSDVGGLE 361

Query: 808 EVRQILMDTIQLPAKYPELF 827
            V+  L++T+Q P+KYPEL 
Sbjct: 362 GVKSSLIETLQWPSKYPELL 421

 Score = 30.4 bits (67), Expect = 4.5,   Method: Compositional matrix adjust.
 Identities = 21/54 (38%), Positives = 29/54 (53%), Gaps = 6/54 (11%)
 Frame = +2

Query: 968  PPDQVSRLEIL--TVLSKSLALA----DDVDLQHVASVTDSFTGADLKALLYNA 1015
            PPD+  R EIL  T+ S S   A    + +DL  VAS T+ F   D++ L+  A
Sbjct: 35   PPDKAGRQEILQCTLKSHSTVCARSTLERLDLDSVASRTEGFVARDIQTLVNRA 196
>20270
          Length = 542

 Score = 90.5 bits (223), Expect(2) = 6e-22,   Method: Compositional matrix adjust.
 Identities = 49/122 (40%), Positives = 74/122 (60%), Gaps = 2/122 (1%)
 Frame = -3

Query: 837 GILLYGPPGTGKTLLAGVVARESGMN-FISIKGPELLSKYIGASEQAVRDVFIRAQAAKP 895
           GILLYGPPGTGK+ LA  VA E+  + F S+   +L+SK++G SE+ V+ +F  A+  +P
Sbjct: 375 GILLYGPPGTGKSYLAKAVATEANNSTFFSVSSSDLVSKWLGESEKLVKTLFQLARENQP 196

Query: 896 CILFFDEFESIAPRRGHDNTGVTDRVVNQLLTQLDGV-EGLQGVYVLAATSRPDLIDPAL 954
            I+F DE +++   R  + +    R+  + L Q+ GV     GV VL AT+ P  +D A+
Sbjct: 195 SIIFIDEVDALCGSRSENESESARRIKTEFLVQMQGVGNDNTGVLVLGATNIPWTLDSAI 16

Query: 955 LR 956
            R
Sbjct: 15  RR 10

 Score = 33.1 bits (74), Expect(2) = 6e-22,   Method: Compositional matrix adjust.
 Identities = 14/43 (32%), Positives = 27/43 (62%)
 Frame = -1

Query: 785 ASLRNVNLHKPRDLGWDKIGGLHEVRQILMDTIQLPAKYPELF 827
           +++R+  + KP ++ WD + GL+  +  L + + LP K+P LF
Sbjct: 524 SAVRSHVVEKP-NVRWDDVAGLNGAKDALKEAVILPVKFPHLF 399

 Score = 35.4 bits (80), Expect = 0.13,   Method: Compositional matrix adjust.
 Identities = 27/86 (31%), Positives = 40/86 (46%)
 Frame = -3

Query: 555 ALLITGGKGSGKSTFAKAICKEAQDTLDARVETVDCKALRGKRLESIQKALEVAFSEAAW 614
            +L+ G  G+GKS  AKA+  EA ++    V + D   L  K L   +K ++  F  A  
Sbjct: 375 GILLYGPPGTGKSYLAKAVATEANNSTFFSVSSSD---LVSKWLGESEKLVKTLFQLARE 205

Query: 615 RQPSVIXXXXXXXIAGLPSVPEQEHS 640
            QPS+I       + G  S  E E +
Sbjct: 204 NQPSIIFIDEVDALCGSRSENESESA 127
>38672
          Length = 730

 Score = 92.4 bits (228), Expect = 1e-18,   Method: Compositional matrix adjust.
 Identities = 51/114 (44%), Positives = 72/114 (63%)
 Frame = -3

Query: 908  PRRGHDNTGVTDRVVNQLLTQLDGVEGLQGVYVLAATSRPDLIDPALLRPGRLDKCVYCP 967
            P+    +  V  R+V+QLLT +DG++    V V+AAT+RP+ +D AL R GR D+ V   
Sbjct: 620  PKERETHGEVERRIVSQLLTLMDGLKQRSHVIVMAATNRPNSVDAALRRFGRFDREVDIG 441

Query: 968  PPDQVSRLEILTVLSKSLALADDVDLQHVASVTDSFTGADLKALLYNAQLEALQ 1021
             PD   RLEIL + +K++ LADDVDL+ VAS T    GAD+ AL   A L+ ++
Sbjct: 440  IPDATGRLEILRIHTKNMKLADDVDLEQVASETHGHVGADVAALCSEAALQQIR 279

 Score = 55.1 bits (131), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 41/151 (27%), Positives = 64/151 (42%), Gaps = 11/151 (7%)
 Frame = -3

Query: 701 PNPEQRCEILHSVVKNKLGCDISNFPDLDLQCIAKDTEAFVARDFTVLVDRA-------- 752
           P+   R EIL    KN    D     D+DL+ +A +T   V  D   L   A        
Sbjct: 437 PDATGRLEILRIHTKNMKLAD-----DVDLEQVASETHGHVGADVAALCSEAALQQIREK 273

Query: 753 ---IXXXXXXXXXXXXEDLTLTTSDFQKALRGFLPASLRNVNLHKPRDLGWDKIGGLHEV 809
              I            + L +T  DF+ AL    P++LR   +  P ++ W+ +GGL  V
Sbjct: 272 MDLIDLEDDTIDAEVLDSLAVTMDDFRWALGKSNPSALRETCVEVP-NVSWEDVGGLENV 96

Query: 810 RQILMDTIQLPAKYPELFANLPIRQRTGILL 840
           ++ L + +Q P ++PE F    +    G+L 
Sbjct: 95  KKELQELVQYPVEHPEKFLKFGMTPSKGVLF 3
>00810
          Length = 1431

 Score = 89.7 bits (221), Expect = 6e-18,   Method: Compositional matrix adjust.
 Identities = 68/220 (30%), Positives = 115/220 (52%), Gaps = 4/220 (1%)
 Frame = -3

Query: 806  LHEVRQILMDTIQLPAKYPELFANLPIRQR-TGILLYGPPGTGKTLLAGVVARESGMNFI 864
            L +V Q + +T+ LP K  +LF +  + Q   G+LL+GPPG GKT++A   A+ +G  FI
Sbjct: 1429 LEDVIQDVKETVILPFKRADLFRHSSLLQPPKGVLLHGPPGCGKTMIAKATAKAAGARFI 1250

Query: 865  SIKGPELLSKYIGASEQAVRDVFIRAQAAKPCILFFDEFESIAPRRGHDNTGVTDRVVNQ 924
            +++   L+ K+ G S++    VF  A   +P I+F DE +S    R   +   T  +  Q
Sbjct: 1249 NLQVSSLVDKWYGESQKRAEAVFSLAIKLQPTIIFIDEIDSFLRSRTSTDHEATAMIKTQ 1070

Query: 925  LLTQLDGV--EGLQGVYVLAATSRPDLIDPALLRPGRLDKCVYCPPPDQVSRLEILT-VL 981
             ++  DG+  +    V V+ AT+RP  +D A+LR  R+    +   P    R  I   +L
Sbjct: 1069 FMSFWDGLMTDPDCRVMVMGATNRPQDVDAAILR--RMPSMFHIGLPGPAQRRSIFNLIL 896

Query: 982  SKSLALADDVDLQHVASVTDSFTGADLKALLYNAQLEALQ 1021
            SK     D ++   +A +TD F+G+D++ +   A +  + 
Sbjct: 895  SKE--RIDALNYDELAEMTDGFSGSDIREVCRAAAVATVH 782
>25671
          Length = 441

 Score = 72.8 bits (177), Expect = 7e-13,   Method: Compositional matrix adjust.
 Identities = 45/108 (41%), Positives = 62/108 (57%), Gaps = 6/108 (5%)
 Frame = +2

Query: 846 TGKTLLAGVVARESGMNFISIKGPELLSKYIGASEQAVRDVFIRAQAAKPCILFFDEFES 905
           TGKT+LA  VA E G  F ++    L +KY G SE+ VR +F  A    P  +F DE +S
Sbjct: 2   TGKTMLAKAVATECGTTFFNVSTSSLANKYRGESEKLVRLLFEMAHFYAPSTIFIDEIDS 181

Query: 906 IAPRRGHDNTG-VTDRVVNQLLTQLDGV-----EGLQGVYVLAATSRP 947
           I  +RG D+    + RV ++LL Q+DGV     +  + V VLAAT+ P
Sbjct: 182 ICSKRGSDSEHEASRRVKSELLVQMDGVGVTNDDPSKAVMVLAATNFP 325
>26408
          Length = 463

 Score = 60.1 bits (144), Expect = 5e-09,   Method: Composition-based stats.
 Identities = 29/49 (59%), Positives = 35/49 (71%)
 Frame = +1

Query: 811 QILMDTIQLPAKYPELFANLPIRQRTGILLYGPPGTGKTLLAGVVARES 859
           Q + + I+LP K+PELF  L I Q  G+LLYGPPGTGKTLLA  VA  +
Sbjct: 292 QRIKEVIELPVKHPELFDALGIAQPKGVLLYGPPGTGKTLLARAVAHHT 438
>17843
          Length = 772

 Score = 55.5 bits (132), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 46/160 (28%), Positives = 72/160 (45%), Gaps = 20/160 (12%)
 Frame = +1

Query: 838 ILLYGPPGTGKTLLAGVVA---------RESGMNFISIKGPELLSKYIGASEQAVRDVFI 888
           ILL+GPPGTGKT L   +A         R S    + I    L SK+   S + V  +F 
Sbjct: 193 ILLHGPPGTGKTTLCKALAHKLCIRLSHRFSCGQLVEINSHSLFSKWFSESGKLVTKMFQ 372

Query: 889 RAQ--AAKP----CILFFDEFESIAPRR-----GHDNTGVTDRVVNQLLTQLDGVEGLQG 937
           R       P    C+L  DE ES+   R     G++ +    RVVN +LTQ+D ++    
Sbjct: 373 RLHDYMVDPELLVCVL-IDEVESLTAARKSCLNGNEPSDAI-RVVNAVLTQIDQLKKFAN 546

Query: 938 VYVLAATSRPDLIDPALLRPGRLDKCVYCPPPDQVSRLEI 977
             +L  ++    ID A +    + + +  P P  + ++ +
Sbjct: 547 CLILTTSNITGAIDLAFVDRADIKQYIGPPTPPAIYKIYL 666
>02194
          Length = 1891

 Score = 48.1 bits (113), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 40/144 (27%), Positives = 61/144 (42%), Gaps = 6/144 (4%)
 Frame = -1

Query: 824  PELFANLPIRQRTGILLYGPPGTGKTLLAGVVARESGMNFISIKGPELLSKYIGASEQAV 883
            P  + +  I  R G LLYGPPG GK+     +A     N   +   E      G S+  +
Sbjct: 1531 PRWYMDRGIPYRRGYLLYGPPGCGKSSYIMALAGALDYNICVLNLSE-----KGLSDDRL 1367

Query: 884  RDVFIRAQAAKPCILFFDEFESIAPRRGHDNT------GVTDRVVNQLLTQLDGVEGLQG 937
              +     A +  I+  ++ ++    R           G+     + LL  LDGV   + 
Sbjct: 1366 NHLL--TVAPEQSIILLEDVDAAFLSRDLSKENPAMYQGMGRLTFSGLLNALDGVASAEA 1193

Query: 938  VYVLAATSRPDLIDPALLRPGRLD 961
              V   T+  D +DPAL+RPGR+D
Sbjct: 1192 RIVFMTTNYLDRLDPALIRPGRVD 1121
>06766
          Length = 976

 Score = 47.8 bits (112), Expect = 3e-05,   Method: Composition-based stats.
 Identities = 25/57 (43%), Positives = 33/57 (57%)
 Frame = +2

Query: 959  RLDKCVYCPPPDQVSRLEILTVLSKSLALADDVDLQHVASVTDSFTGADLKALLYNA 1015
            RLD+ +Y P PD  SR  IL    +   LA +VDL ++A VT  F+GADL  +   A
Sbjct: 2    RLDQLIYIPLPDDKSREAILKANLRKSPLAKEVDLTYIAKVTQGFSGADLTEICQRA 172
>14413
          Length = 826

 Score = 41.2 bits (95), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 34/123 (27%), Positives = 56/123 (45%), Gaps = 9/123 (7%)
 Frame = +2

Query: 862 NFISIKGPELLSKYIGASEQAVRDVFIRA------QAAKPCILFFDEFESIAPRRGHDNT 915
           + + I    L SK+   S + V  +F +       +    C+L  DE ES+A  R   ++
Sbjct: 71  HLVEINSHSLFSKWFSESGKLVARLFGKIGELATDKNNLVCVLI-DEVESLAYARSAMSS 247

Query: 916 GV---TDRVVNQLLTQLDGVEGLQGVYVLAATSRPDLIDPALLRPGRLDKCVYCPPPDQV 972
                  RVVN +LTQLD ++    V +LA ++    ID A L    + + +  P P  +
Sbjct: 248 NEPRDAMRVVNAVLTQLDEIKACPNVLILATSNLAQSIDLAFLDRADIRQFIGLPDPLAI 427

Query: 973 SRL 975
           S +
Sbjct: 428 SSI 436
>05247
          Length = 375

 Score = 29.6 bits (65), Expect(2) = 0.005,   Method: Composition-based stats.
 Identities = 10/25 (40%), Positives = 17/25 (68%)
 Frame = +2

Query: 959 RLDKCVYCPPPDQVSRLEILTVLSK 983
           R+D+ +Y PPPD   RL+  T+ ++
Sbjct: 2   RMDRLIYVPPPDVQGRLQSFTIHTR 76

 Score = 29.6 bits (65), Expect(2) = 0.005,   Method: Composition-based stats.
 Identities = 13/29 (44%), Positives = 19/29 (65%)
 Frame = +1

Query: 983  KSLALADDVDLQHVASVTDSFTGADLKAL 1011
            K + L  DVD++ +A +T   TGAD+K L
Sbjct: 73   KKMPLGKDVDVKQLADLTAG*TGADIKTL 159
>19561
          Length = 474

 Score = 40.0 bits (92), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 26/72 (36%), Positives = 37/72 (51%), Gaps = 5/72 (6%)
 Frame = -1

Query: 839 LLYGPPGTGKTLLAGVVARESGMNFISI-----KGPELLSKYIGASEQAVRDVFIRAQAA 893
           LL GPPG GKT LA +VA+ +G N + +     +  E+ S  I A+ Q +R V       
Sbjct: 369 LLCGPPGLGKTTLAHIVAKHAGYNVVEMNASDDRSVEVFSNKIEAATQ-MRAVM--GADP 199

Query: 894 KPCILFFDEFES 905
           +P  L  DE + 
Sbjct: 198 RPNCLIIDEIDG 163
>29846
          Length = 451

 Score = 39.3 bits (90), Expect = 0.010,   Method: Compositional matrix adjust.
 Identities = 18/48 (37%), Positives = 29/48 (60%)
 Frame = +1

Query: 969  PDQVSRLEILTVLSKSLALADDVDLQHVASVTDSFTGADLKALLYNAQ 1016
            P  + R +I     + L LA D+DL  ++SVT  + GAD+KA+  +A+
Sbjct: 157  PTSIQRRQIFNFCLRKLPLASDLDLDWLSSVTAGYVGADIKAVCASAR 300
>15498
          Length = 769

 Score = 37.4 bits (85), Expect = 0.034,   Method: Compositional matrix adjust.
 Identities = 27/96 (28%), Positives = 44/96 (45%)
 Frame = -1

Query: 782 FLPASLRNVNLHKPRDLGWDKIGGLHEVRQILMDTIQLPAKYPELFANLPIRQRTGILLY 841
           +L  +LR  N+        + +  L +VR+++ +   LP   P +    P+ +   ILL 
Sbjct: 316 YLGTTLRQANI--------EPMPSLSDVRRLVTEFGILPLGSPSVHEQAPLTKS--ILLA 167

Query: 842 GPPGTGKTLLAGVVARESGMNFISIKGPELLSKYIG 877
           GP G+GK +L   +  E G N   +    L  KY G
Sbjct: 166 GPRGSGKKMLVHALCNEVGANLFDLSPANLAGKYPG 59
>01279
          Length = 2183

 Score = 37.0 bits (84), Expect = 0.053,   Method: Composition-based stats.
 Identities = 29/106 (27%), Positives = 51/106 (48%), Gaps = 6/106 (5%)
 Frame = -3

Query: 837  GILLYGPPGTGKTLLAGVVARESG--MNFISIKGPELLSKYIGASEQAV----RDVFIRA 890
             +LL GPPGTGKT +A  +A+E G  + F  + G E+ S  I  +E  +    R + +R 
Sbjct: 1911 AVLLAGPPGTGKTAIALAIAQELGNKVPFCPMVGSEVYSSEIKKTEVLMENFRRAIGLRI 1732

Query: 891  QAAKPCILFFDEFESIAPRRGHDNTGVTDRVVNQLLTQLDGVEGLQ 936
            +  K   ++  E   + P    +  G   + V+ ++  L   +G +
Sbjct: 1731 KETKE--VYEGEVTELTPVETENPMGGYGKTVSHVVIGLKTAKGTK 1600
>08000
          Length = 343

 Score = 32.0 bits (71), Expect = 1.7,   Method: Composition-based stats.
 Identities = 12/30 (40%), Positives = 21/30 (70%)
 Frame = +3

Query: 982  SKSLALADDVDLQHVASVTDSFTGADLKAL 1011
            ++ + L  DVD++ +A +T  +TGAD+K L
Sbjct: 12   TQEMPLGKDVDVKQLADLTAGYTGADIKTL 101
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|21703836|ref|NP_663394.1| hexokinase domain
containing 1 [Mus musculus]
         (915 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

02988                                                                 191   1e-48
19439                                                                 165   8e-41
09654                                                                 154   2e-37
30474                                                                  44   3e-04
06327                                                                  35   0.14 
04618                                                                  29   9.5  
>02988
          Length = 1673

 Score =  191 bits (485), Expect = 1e-48,   Method: Compositional matrix adjust.
 Identities = 100/203 (49%), Positives = 137/203 (67%), Gaps = 2/203 (0%)
 Frame = +3

Query: 708 GFGDNGCIDDIRTQYDKEVDEGSLNAGKQRYEKMTSGMYLGEIVRRILIDLTRQGLLFRG 767
            FGD+GC+D I T +D++VD+ S+NAGKQRYEK  SGMY+GEIVR  L  L + GLLF G
Sbjct: 3   AFGDDGCLDFITTDFDRQVDKHSINAGKQRYEKFISGMYMGEIVRLALEKLRKNGLLFGG 182

Query: 768 QISERLRTRGIFETKFLSQIESDRLALLQ-VRRILQQLGLDSTCE-DSIVVKEVCGAVSR 825
           + S  + TRG F TK++S+IE+D     +  ++I ++L +D+  E D  +V+ VC  VSR
Sbjct: 183 EGSYHMATRGRFYTKYVSEIEADDQETFKTTKQIFEELEIDTVTEQDCRLVRHVCSLVSR 362

Query: 826 RAAQMCGAGMAAIVEKRREDQGLQHFKVTVGVDGTLYKLHPHFSRILQETVKELAPQCDV 885
           RAA +  AG++ ++ K +  +      VTVGVDG+LY+ HP F  ++ E  K LAP    
Sbjct: 363 RAAYLAAAGVSCLLNKMKRPE------VTVGVDGSLYRFHPFFHDLMMEKTKVLAPGIRY 524

Query: 886 TFMLSEDGSGKGAALITAVAKRL 908
            FMLSEDGSGKGAAL+ AVA R+
Sbjct: 525 KFMLSEDGSGKGAALVAAVANRI 593

 Score =  162 bits (411), Expect = 4e-40,   Method: Compositional matrix adjust.
 Identities = 89/207 (42%), Positives = 131/207 (63%), Gaps = 2/207 (0%)
 Frame = +3

Query: 263 AFGDDGALEDIRTEFDRELDLGSLNPGKQLFEKMISGLYMGELVRLILLKMAKVGLLFGG 322
           AFGDDG L+ I T+FDR++D  S+N GKQ +EK ISG+YMGE+VRL L K+ K GLLFGG
Sbjct: 3   AFGDDGCLDFITTDFDRQVDKHSINAGKQRYEKFISGMYMGEIVRLALEKLRKNGLLFGG 182

Query: 323 AKSSALHTKGKIETQHVAAMEM-SKEGLANTREILVDLGLEP-SESDCIAVQHVCTIVSF 380
             S  + T+G+  T++V+ +E   +E    T++I  +L ++  +E DC  V+HVC++VS 
Sbjct: 183 EGSYHMATRGRFYTKYVSEIEADDQETFKTTKQIFEELEIDTVTEQDCRLVRHVCSLVSR 362

Query: 381 RSANXXXXXXXXXXXXXXENKKLARLRTTVGMDGTLYKTHPQYPKRLHKVVRRLVPNCDV 440
           R+A                  K+ R   TVG+DG+LY+ HP +   + +  + L P    
Sbjct: 363 RAAYLAAAGVSCLL------NKMKRPEVTVGVDGSLYRFHPFFHDLMMEKTKVLAPGIRY 524

Query: 441 RFLLSESGSTKGAAMVTAVASRVQAQR 467
           +F+LSE GS KGAA+V AVA+R+ A++
Sbjct: 525 KFMLSEDGSGKGAALVAAVANRILAEQ 605
>19439
          Length = 417

 Score =  165 bits (418), Expect = 8e-41,   Method: Compositional matrix adjust.
 Identities = 74/137 (54%), Positives = 100/137 (72%), Gaps = 3/137 (2%)
 Frame = +1

Query: 133 CLADFMKTKNLTHKKLPLGFTFSFPCRQNKLEEGVLLSWTKKFKARGVQDTDVVNRLATA 192
           C++ F+K  +L  +KLPLGFTFSFPCRQ+ L   VL +WTK FK  GV+  ++VN L  A
Sbjct: 1   CISRFVKEHDLGGRKLPLGFTFSFPCRQHGLANAVLTTWTKGFKCEGVEGNNIVNLLHEA 180

Query: 193 MKKHKDLDVDILALVNDTVGTMMTCAYDDPNCEVGVIIGTGTNACYMEDMSNIDLVEGDE 252
           +++  DL+V  LA++NDTVG +M+CA+ D  C VG+I+GTGTNACY+E + N+ + EG+E
Sbjct: 181 IQRKGDLEVQCLAVINDTVGALMSCAHSDRQCAVGIILGTGTNACYIERLENVQMAEGNE 360

Query: 253 G---RMCINTEWGAFGD 266
                M INTEWGAFGD
Sbjct: 361 PGPQEMLINTEWGAFGD 411

 Score =  150 bits (380), Expect = 2e-36,   Method: Compositional matrix adjust.
 Identities = 64/137 (46%), Positives = 95/137 (69%), Gaps = 3/137 (2%)
 Frame = +1

Query: 578 CIADFLDYMGLKGAQLPLGFTFSFPCRQTCIDKGTLVGWTKGFKATDCEGEDVVDMLREA 637
           CI+ F+    L G +LPLGFTFSFPCRQ  +    L  WTKGFK    EG ++V++L EA
Sbjct: 1   CISRFVKEHDLGGRKLPLGFTFSFPCRQHGLANAVLTTWTKGFKCEGVEGNNIVNLLHEA 180

Query: 638 IKRRNEFDLDIVAIVNDTVGTMMTCGYEDPRCEIGLIAGTGSNVCYMEEMRNIELVDGDE 697
           I+R+ + ++  +A++NDTVG +M+C + D +C +G+I GTG+N CY+E + N+++ +G+E
Sbjct: 181 IQRKGDLEVQCLAVINDTVGALMSCAHSDRQCAVGIILGTGTNACYIERLENVQMAEGNE 360

Query: 698 G---RMCVNTEWGGFGD 711
                M +NTEWG FGD
Sbjct: 361 PGPQEMLINTEWGAFGD 411
>09654
          Length = 1044

 Score =  154 bits (388), Expect = 2e-37,   Method: Compositional matrix adjust.
 Identities = 95/207 (45%), Positives = 134/207 (64%), Gaps = 4/207 (1%)
 Frame = +3

Query: 708 GFGDNGCIDDIRTQYDKEVDEGSLNAGKQRYEKMTSGMYLGEIVRRILIDLTRQGLLFRG 767
            FGDNGC+D +RT+YD+E+D  S+N GKQ  EKM SGMY+GEIVR +L  LT +GLLFR 
Sbjct: 3   AFGDNGCLDFLRTEYDRELDTFSINPGKQIMEKMISGMYMGEIVRLVLERLTMEGLLFRS 182

Query: 768 QISE-RLRTRGIFETKFLSQIESDRLALLQ-VRRILQQLGLDS-TCEDSIVVKEVCGAVS 824
             +E  L  RG F TK++S+IE D     +  +++L++LG+++ T ED  VVK VC  +S
Sbjct: 183 IDNESELFERGRFYTKYVSEIECDTDEFFRNTKQVLEELGVENYTTEDCKVVKYVCTLIS 362

Query: 825 RRAAQMCGAGMAAIVEKRREDQGLQHFKVTVGVDGTLYKLHPHFSRILQETVKELA-PQC 883
            RAA +  AG+A ++ K  + +      +T+ VDG+LY+ HP F  ++   ++EL  P  
Sbjct: 363 ARAAFLAAAGLATLINKMNKSE------ITIAVDGSLYRFHPRFHNLMCLKIQELVKPGL 524

Query: 884 DVTFMLSEDGSGKGAALITAVAKRLQQ 910
                LS DGSGKGAAL  AV+ RL+ 
Sbjct: 525 KFKLSLSHDGSGKGAALTAAVSLRLRN 605

 Score =  141 bits (355), Expect = 1e-33,   Method: Compositional matrix adjust.
 Identities = 82/206 (39%), Positives = 128/206 (62%), Gaps = 4/206 (1%)
 Frame = +3

Query: 263 AFGDDGALEDIRTEFDRELDLGSLNPGKQLFEKMISGLYMGELVRLILLKMAKVGLLFGG 322
           AFGD+G L+ +RTE+DRELD  S+NPGKQ+ EKMISG+YMGE+VRL+L ++   GLLF  
Sbjct: 3   AFGDNGCLDFLRTEYDRELDTFSINPGKQIMEKMISGMYMGEIVRLVLERLTMEGLLFRS 182

Query: 323 AKS-SALHTKGKIETQHVAAMEM-SKEGLANTREILVDLGLEP-SESDCIAVQHVCTIVS 379
             + S L  +G+  T++V+ +E  + E   NT+++L +LG+E  +  DC  V++VCT++S
Sbjct: 183 IDNESELFERGRFYTKYVSEIECDTDEFFRNTKQVLEELGVENYTTEDCKVVKYVCTLIS 362

Query: 380 FRSANXXXXXXXXXXXXXXENKKLARLRTTVGMDGTLYKTHPQYPKRLHKVVRRLV-PNC 438
            R+A                  K+ +   T+ +DG+LY+ HP++   +   ++ LV P  
Sbjct: 363 ARAAFLAAAGLATLI------NKMNKSEITIAVDGSLYRFHPRFHNLMCLKIQELVKPGL 524

Query: 439 DVRFLLSESGSTKGAAMVTAVASRVQ 464
             +  LS  GS KGAA+  AV+ R++
Sbjct: 525 KFKLSLSHDGSGKGAALTAAVSLRLR 602
>30474
          Length = 424

 Score = 43.9 bits (102), Expect = 3e-04,   Method: Composition-based stats.
 Identities = 19/39 (48%), Positives = 27/39 (69%)
 Frame = +1

Query: 39  IMARFQAEMEKGLGKDTNPTASVKMLPTFVRAIPDGSEN 77
           + +R   +  +G    TN TASVKM PT+VRA+PDG+E+
Sbjct: 307 LCSRCWTKWRRGWVAGTNDTASVKMFPTYVRAVPDGTES 423

 Score = 35.0 bits (79), Expect = 0.13,   Method: Composition-based stats.
 Identities = 14/22 (63%), Positives = 17/22 (77%)
 Frame = +1

Query: 503 THSLATVKMLPTYVYGMPDGTE 524
           T+  A+VKM PTYV  +PDGTE
Sbjct: 355 TNDTASVKMFPTYVRAVPDGTE 420
>06327
          Length = 827

 Score = 35.0 bits (79), Expect = 0.14,   Method: Composition-based stats.
 Identities = 18/25 (72%), Positives = 21/25 (84%), Gaps = 2/25 (8%)
 Frame = -2

Query: 885 VTF--MLSEDGSGKGAALITAVAKR 907
           +TF  MLSEDGSG+GAAL+ AVA R
Sbjct: 826 ITFDLMLSEDGSGRGAALVAAVACR 752
>04618
          Length = 1663

 Score = 28.9 bits (63), Expect = 9.5,   Method: Compositional matrix adjust.
 Identities = 24/87 (27%), Positives = 43/87 (49%)
 Frame = -3

Query: 460  ASRVQAQRKQIDKVLALFQLTREQLLGVRDKMRAELEYGLKKKTHSLATVKMLPTYVYGM 519
            A+++  Q++Q+ + LA  QL +EQL  + + +R E E    + +   +TVK L      +
Sbjct: 1004 ATQLDGQKEQLQRRLAALQLEKEQLHSLVEDLRQESECLQDQVSQERSTVKNLEAL---L 834

Query: 520  PDGTEKGKFLALDLGGTNFRVLLVKIR 546
             +G EK     L     N  + ++K R
Sbjct: 833  QNGREKEFQNQLSSQERNTEIQMLKDR 753
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|165932270|ref|NP_080451.4| splicing factor 3a,
subunit 1 [Mus musculus]
         (791 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

38457                                                                 190   2e-48
14135                                                                 175   8e-44
25295                                                                 129   4e-30
30439                                                                  52   9e-07
04017                                                                  49   7e-06
04649                                                                  47   3e-05
00758                                                                  46   5e-05
13455                                                                  46   5e-05
03942                                                                  44   3e-04
08296                                                                  42   7e-04
09082                                                                  39   0.006
34270                                                                  35   0.033
24173                                                                  33   0.32 
>38457
          Length = 662

 Score =  190 bits (482), Expect = 2e-48,   Method: Compositional matrix adjust.
 Identities = 96/142 (67%), Positives = 116/142 (81%), Gaps = 2/142 (1%)
 Frame = +1

Query: 406 DEYLVSPITGEKIPASKMQEHMRIGLLDPRWLEQRDRSIREKQSDDEVYAPGLDIESSLK 465
           DEYL+SPITGEKIPASK+ EHMRIGLLDPRW+EQRD+   EK + D V+A G  IE+SLK
Sbjct: 7   DEYLISPITGEKIPASKVSEHMRIGLLDPRWVEQRDKHTVEKINQDNVFAAGTAIEASLK 186

Query: 466 QLAERRTDIFGV--EETAIGKKIGEEEIQKPEEKVTWDGHSGSMARTQQAAQANITLQEQ 523
           QLAERRTDIFGV  EET IGKK+GEEE +K +++VTWDGH+ S+    +AA+ANITL++Q
Sbjct: 187 QLAERRTDIFGVGDEETVIGKKLGEEETKK-DDRVTWDGHTSSVEAATRAARANITLEDQ 363

Query: 524 IEAIHKAKGLVPEDDTKEKIGP 545
           I  IHK KGL+  D+ KEKIGP
Sbjct: 364 IHQIHKVKGLL-HDEEKEKIGP 426
>14135
          Length = 567

 Score =  175 bits (443), Expect = 8e-44,   Method: Compositional matrix adjust.
 Identities = 81/118 (68%), Positives = 97/118 (82%)
 Frame = +2

Query: 674 MEDEPPSKKLKTEDSLMPEEEFLRRNKGPVSIKVQVPNMQDKTEWKLNGQGLVFTLPLTD 733
           M DEPP+KK KTED+L+PE  FL+RNK PV +KV VPN+ DK EWKLNGQ L F+LPLTD
Sbjct: 47  MSDEPPNKKQKTEDNLIPENVFLQRNKSPVMVKVMVPNVNDKPEWKLNGQTLEFSLPLTD 226

Query: 734 QVSVIKVKIHEATGMPAGKQKLQYEGIFIKDSNSLAYYNMASGAVIHLALKERGGRKK 791
            +SV+K K++E  GMPAGKQKLQYEGIF+KDSN+LA+YN   GA + L +KERGGRKK
Sbjct: 227 TISVLKAKLNEVLGMPAGKQKLQYEGIFVKDSNTLAFYNFMMGATVQLQMKERGGRKK 400
>25295
          Length = 998

 Score =  129 bits (325), Expect = 4e-30,   Method: Compositional matrix adjust.
 Identities = 58/83 (69%), Positives = 69/83 (83%)
 Frame = -2

Query: 709 VPNMQDKTEWKLNGQGLVFTLPLTDQVSVIKVKIHEATGMPAGKQKLQYEGIFIKDSNSL 768
           VPN+ DK EWKLNGQ L F+LPLTD +SV+K K++E  GMPAGKQKLQYEGIF+KDSN+L
Sbjct: 997 VPNVNDKPEWKLNGQTLEFSLPLTDTISVLKAKLNEVLGMPAGKQKLQYEGIFVKDSNTL 818

Query: 769 AYYNMASGAVIHLALKERGGRKK 791
           A+YN   GA + L +KERGGRKK
Sbjct: 817 AFYNFMMGATVQLQMKERGGRKK 749
>30439
          Length = 741

 Score = 52.0 bits (123), Expect = 9e-07,   Method: Compositional matrix adjust.
 Identities = 33/88 (37%), Positives = 43/88 (48%), Gaps = 7/88 (7%)
 Frame = +3

Query: 24  EEEASSKEDP-----TPSKPVVGIIYPPPEVR-NIVDKTASFVARNGPEFEARIRQNEIN 77
           E     KEDP     T +K VV +  P    + N++ +   FV R GP FEA I   E+ 
Sbjct: 18  ENRPDKKEDPEDQEKTLAKAVVKVTIPTERAQLNLIHRMIEFVVREGPMFEAMIMNRELQ 197

Query: 78  NPKFNFLNPN-DPYHAYYRHKVSEFKEG 104
           NP+F FL  N    H YYR K+    +G
Sbjct: 198 NPQFRFLFENQSANHLYYRWKLFSILQG 281
>04017
          Length = 690

 Score = 48.9 bits (115), Expect = 7e-06,   Method: Compositional matrix adjust.
 Identities = 23/72 (31%), Positives = 42/72 (58%)
 Frame = -1

Query: 720 LNGQGLVFTLPLTDQVSVIKVKIHEATGMPAGKQKLQYEGIFIKDSNSLAYYNMASGAVI 779
           L G+ +   +  +D +  +K KI +  G+P  +Q+L + G  ++D  +L+ YN+   + +
Sbjct: 321 LTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTL 142

Query: 780 HLALKERGGRKK 791
           HL L+ RGG KK
Sbjct: 141 HLVLRLRGGAKK 106
>04649
          Length = 1590

 Score = 47.0 bits (110), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 21/69 (30%), Positives = 40/69 (57%)
 Frame = -2

Query: 720 LNGQGLVFTLPLTDQVSVIKVKIHEATGMPAGKQKLQYEGIFIKDSNSLAYYNMASGAVI 779
           L G+ +   +  +D +  +K KI +  G+P  +Q+L + G  ++D  +L+ YN+   + +
Sbjct: 428 LTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTL 249

Query: 780 HLALKERGG 788
           HL L+ RGG
Sbjct: 248 HLVLRLRGG 222
>00758
          Length = 1050

 Score = 46.2 bits (108), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 21/69 (30%), Positives = 40/69 (57%)
 Frame = +1

Query: 720 LNGQGLVFTLPLTDQVSVIKVKIHEATGMPAGKQKLQYEGIFIKDSNSLAYYNMASGAVI 779
           L G+ +   +  +D +  +K KI +  G+P  +Q+L + G  ++D  +L+ YN+   + +
Sbjct: 544 LTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTL 723

Query: 780 HLALKERGG 788
           HL L+ RGG
Sbjct: 724 HLVLRLRGG 750
>13455
          Length = 809

 Score = 46.2 bits (108), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 21/69 (30%), Positives = 40/69 (57%)
 Frame = +3

Query: 720 LNGQGLVFTLPLTDQVSVIKVKIHEATGMPAGKQKLQYEGIFIKDSNSLAYYNMASGAVI 779
           L G+ +   +  +D +  +K KI +  G+P  +Q+L + G  ++D  +L+ YN+   + +
Sbjct: 378 LTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTL 557

Query: 780 HLALKERGG 788
           HL L+ RGG
Sbjct: 558 HLVLRLRGG 584
>03942
          Length = 912

 Score = 43.5 bits (101), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 20/69 (28%), Positives = 39/69 (56%)
 Frame = +1

Query: 720 LNGQGLVFTLPLTDQVSVIKVKIHEATGMPAGKQKLQYEGIFIKDSNSLAYYNMASGAVI 779
           L G+ +   +  +D +  +K K  +  G+P  +Q+L + G  ++D  +L+ YN+   + +
Sbjct: 427 LTGKTITLEVEPSDTIENVKAKSKDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTL 606

Query: 780 HLALKERGG 788
           HL L+ RGG
Sbjct: 607 HLVLRLRGG 633
>08296
          Length = 897

 Score = 42.4 bits (98), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 21/57 (36%), Positives = 33/57 (57%)
 Frame = +1

Query: 732 TDQVSVIKVKIHEATGMPAGKQKLQYEGIFIKDSNSLAYYNMASGAVIHLALKERGG 788
           TD+V  IK ++ E  G+P  +Q+L + G  + D  +   Y +  G+V+HL L  RGG
Sbjct: 184 TDKVERIKERVEEKEGIPPQQQRLIFSGKQMNDEKTAQDYKVIGGSVLHLVLALRGG 354
>09082
          Length = 1116

 Score = 39.3 bits (90), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 20/57 (35%), Positives = 33/57 (57%)
 Frame = +3

Query: 45  PPPEVRNIVDKTASFVARNGPEFEARIRQNEINNPKFNFLNPNDPYHAYYRHKVSEF 101
           PPP+ + I+D+ A +VA+NG EFE  ++     + +F+FL     +  YY  K + F
Sbjct: 54  PPPDAQPIIDRMAMYVAKNGVEFEFVVKSK--RDERFSFLEEGHVHFQYYDFKKNMF 218
>34270
          Length = 274

 Score = 35.4 bits (80), Expect(2) = 0.033,   Method: Compositional matrix adjust.
 Identities = 15/54 (27%), Positives = 31/54 (57%)
 Frame = +1

Query: 720 LNGQGLVFTLPLTDQVSVIKVKIHEATGMPAGKQKLQYEGIFIKDSNSLAYYNM 773
           L G+ +   +  +D +  +K KI +  G+P  +Q+L + G  ++D  +L+ YN+
Sbjct: 55  LTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNI 216

 Score = 20.4 bits (41), Expect(2) = 0.033,   Method: Compositional matrix adjust.
 Identities = 8/13 (61%), Positives = 10/13 (76%)
 Frame = +2

Query: 779 IHLALKERGGRKK 791
           +HL L+ RGG KK
Sbjct: 233 LHLVLRLRGGAKK 271
>24173
          Length = 413

 Score = 33.5 bits (75), Expect = 0.32,   Method: Composition-based stats.
 Identities = 15/53 (28%), Positives = 30/53 (56%)
 Frame = -2

Query: 735 VSVIKVKIHEATGMPAGKQKLQYEGIFIKDSNSLAYYNMASGAVIHLALKERG 787
           V  +K +I++  G+   +Q+L + G  ++D   L+ YN+   + +HL  + RG
Sbjct: 280 VGELKCQIYDKDGISPEQQRLVFAGKQLEDGRLLSDYNITDDSTLHLVFRLRG 122
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31980994|ref|NP_062769.2| DnaJ (Hsp40) homolog,
subfamily C, member 7 [Mus musculus]
         (494 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

13998                                                                 189   2e-48
35264                                                                 166   1e-41
35348                                                                  71   9e-13
13422                                                                  62   7e-10
07620                                                                  44   9e-10
30337                                                                  60   3e-09
35341                                                                  57   1e-08
01124                                                                  57   2e-08
02324                                                                  56   4e-08
26984                                                                  55   8e-08
08670                                                                  52   4e-07
14550                                                                  52   6e-07
02088                                                                  51   8e-07
23484                                                                  48   7e-06
04645                                                                  43   3e-04
22505                                                                  40   5e-04
00888                                                                  41   0.001
13560                                                                  37   0.017
20155                                                                  34   0.16 
28154                                                                  34   0.17 
03857                                                                  33   0.18 
18150                                                                  26   1.0  
33510                                                                  31   1.1  
22027                                                                  30   1.8  
25094                                                                  30   2.7  
19619                                                                  30   3.1  
10994                                                                  29   3.5  
17683                                                                  29   5.2  
00150                                                                  28   5.9  
>13998
          Length = 1075

 Score =  189 bits (480), Expect = 2e-48,   Method: Compositional matrix adjust.
 Identities = 97/174 (55%), Positives = 123/174 (70%), Gaps = 4/174 (2%)
 Frame = +1

Query: 313 AIEDCTNAVKLDDTYIKAYLRRAQCYMDTEQFEEAVRDYEKVYQTEKTKEHKQLLKNAQL 372
           A+ DC   + L+  Y+KA L RA+C  D E+FEEAV DYE   Q EKT E K+LL++A+ 
Sbjct: 1   AVADCNRVLDLNSQYLKALLLRARCNNDLEKFEEAVADYETALQLEKTPEIKRLLRDAKF 180

Query: 373 ELKKSKRKDYYKILGVDKNASEDEIKKAYRKRALMHHPDRHSGASAEVQXXXXXXXXXVG 432
            LKKSKRKDYYKILG+ +NA+EDEIKKAYRK+AL+HHPDRH+ +SA+V+         VG
Sbjct: 181 ALKKSKRKDYYKILGISRNATEDEIKKAYRKKALVHHPDRHANSSADVRKDEELKFKEVG 360

Query: 433 EAFTILSDPKKKTRYDSGQDLDEEGMNMGDFDANNIFKAFFGGPGG----FSFE 482
           EA+ ILSD  KKTRYDSG D+ +E     DFD N +F++FF   GG    F+FE
Sbjct: 361 EAYAILSDGAKKTRYDSGHDIQDEM--QADFDPNQMFRSFFQFSGGRNSSFNFE 516
>35264
          Length = 867

 Score =  166 bits (420), Expect(3) = 1e-41,   Method: Compositional matrix adjust.
 Identities = 99/258 (38%), Positives = 142/258 (55%), Gaps = 6/258 (2%)
 Frame = +3

Query: 44  YNEAYNYYTKAIDMCPNNASYYGNRAATLMMLGRFREALGDAQQSVRLDDSFVRGHLREG 103
           Y EA   YT AI++CP+ A+YYGNRAAT MML ++RE L DAQQ+V+LD +FV+G++REG
Sbjct: 87  YKEALECYTCAINLCPSCAAYYGNRAATYMMLKKYREGLKDAQQAVQLDPTFVKGYIREG 266

Query: 104 KCHLSLGNAMAACRSFQRALELDHKNAQAQQEFKNANAVMEYEKIAEVDFEKRDFRKVVF 163
           KCHL LGN+MAA  +F R LELD  N+ A  E K    + E E   +++F + + R  ++
Sbjct: 267 KCHLMLGNSMAASSNFNRVLELDAGNSTAVTELKRVKTLQELETKVDLNFVRGEHRTALY 446

Query: 164 CMDRALEFAPACHRFKILKAECLAMLGRYPEAQFVASDILRMDSTNADALYVRGLCLYYE 223
           C+DR LE +PA  RFK+LKAE L+        + +     R          +R LC   +
Sbjct: 447 CLDRCLEHSPASLRFKVLKAEALSFWVDRQRPRNLQMTFYRKTG------*MRTLCT*GD 608

Query: 224 -DCIEKAVQ-----FFVQALRMAPDHEKACVACRNAKALKAKKEDGNKAFKEGNYKLAYE 277
             C  +  Q      F           K  +      + + +K  G +    G  + AY+
Sbjct: 609 *ACTIRTTQRKPSSIFSMPCDWPQTTPKLEMPSEKRSS*QHRKSPGMQPSGRGV*QEAYD 788

Query: 278 LYTEALGIDPNNIKTNAK 295
           LY++AL +DP N  TN+K
Sbjct: 789 LYSKALQVDPXNSSTNSK 842

 Score = 21.6 bits (44), Expect(3) = 1e-41,   Method: Compositional matrix adjust.
 Identities = 8/9 (88%), Positives = 8/9 (88%)
 Frame = +1

Query: 295 KLYCNRGTV 303
           KLYCNR TV
Sbjct: 841 KLYCNRATV 867

 Score = 21.2 bits (43), Expect(3) = 1e-41,   Method: Compositional matrix adjust.
 Identities = 9/22 (40%), Positives = 15/22 (68%)
 Frame = +1

Query: 28 AESFKEQGNAYYAKKDYNEAYN 49
          AES KE+GN +Y +++  +  N
Sbjct: 40 AESKKEEGNEFYKQQNTKKPLN 105

 Score = 46.6 bits (109), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 27/101 (26%), Positives = 51/101 (50%), Gaps = 2/101 (1%)
 Frame = +3

Query: 258 AKKEDG--NKAFKEGNYKLAYELYTEALGIDPNNIKTNAKLYCNRGTVNSKLRQLEDAIE 315
            +K++G   +  +   YK A E YT A+ + P    + A  Y NR      L++  + ++
Sbjct: 39  GRKQEGRRQRVLQAAKYKEALECYTCAINLCP----SCAAYYGNRAATYMMLKKYREGLK 206

Query: 316 DCTNAVKLDDTYIKAYLRRAQCYMDTEQFEEAVRDYEKVYQ 356
           D   AV+LD T++K Y+R  +C++       A  ++ +V +
Sbjct: 207 DAQQAVQLDPTFVKGYIREGKCHLMLGNSMAASSNFNRVLE 329
>35348
          Length = 627

 Score = 71.2 bits (173), Expect = 9e-13,   Method: Compositional matrix adjust.
 Identities = 40/112 (35%), Positives = 64/112 (57%), Gaps = 1/112 (0%)
 Frame = -2

Query: 251 RNAKALKAKKEDGNKAFKEGNYKLAYELYTEALGIDP-NNIKTNAKLYCNRGTVNSKLRQ 309
           R A+A+K K   GN  FK G Y  A ELY+E L I P   ++  + +  NR     K   
Sbjct: 596 RLAEAVKVKVR-GNDTFKSGQYAEALELYSEGLDICPLKYVQQRSVMLSNRAACRIKKED 420

Query: 310 LEDAIEDCTNAVKLDDTYIKAYLRRAQCYMDTEQFEEAVRDYEKVYQTEKTK 361
            + A+ DCT ++ L+  YIKAY RRA  Y   E+ ++A++D+ +V + ++++
Sbjct: 419 YQKAVGDCTKSIDLNPAYIKAYFRRADAYEKLEKLDDALKDHRQVVEMDRSQ 264

 Score = 47.4 bits (111), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 27/113 (23%), Positives = 54/113 (47%), Gaps = 5/113 (4%)
 Frame = -2

Query: 27  EAESFKEQGNAYYAKKDYNEAYNYYTKAIDMCP-----NNASYYGNRAATLMMLGRFREA 81
           EA   K +GN  +    Y EA   Y++ +D+CP       +    NRAA  +    +++A
Sbjct: 587 EAVKVKVRGNDTFKSGQYAEALELYSEGLDICPLKYVQQRSVMLSNRAACRIKKEDYQKA 408

Query: 82  LGDAQQSVRLDDSFVRGHLREGKCHLSLGNAMAACRSFQRALELDHKNAQAQQ 134
           +GD  +S+ L+ ++++ + R    +  L     A +  ++ +E+D     + Q
Sbjct: 407 VGDCTKSIDLNPAYIKAYFRRADAYEKLEKLDDALKDHRQVVEMDRSQIDSIQ 249
>13422
          Length = 930

 Score = 61.6 bits (148), Expect = 7e-10,   Method: Compositional matrix adjust.
 Identities = 34/105 (32%), Positives = 56/105 (53%), Gaps = 4/105 (3%)
 Frame = +1

Query: 372 LELKKSKRKDYYKILGVDK---NASEDEIKKAYRKRALMHHPDRHSGASAEVQXXXXXXX 428
           L  K+ K++D+Y +LG+ K    A+ D IK+ YR++ L+HHPD+       V+       
Sbjct: 310 LNPKEWKKQDHYAVLGLSKLRYKATADHIKRIYRQKVLLHHPDKRRARGLHVENGENDYF 489

Query: 429 XXVGEAFTILSDPKKKTRYDS-GQDLDEEGMNMGDFDANNIFKAF 472
             +  A+ IL DP K+  +DS   + DE   ++   + +N FK F
Sbjct: 490 LCISRAYEILGDPVKRRSFDSVDPEFDEAVPSLCQENKDNFFKVF 624
>07620
          Length = 1775

 Score = 44.3 bits (103), Expect(2) = 9e-10,   Method: Compositional matrix adjust.
 Identities = 19/33 (57%), Positives = 26/33 (78%)
 Frame = +1

Query: 380 KDYYKILGVDKNASEDEIKKAYRKRALMHHPDR 412
           KDYY++L V K+ +E ++KKAYRK AL  HPD+
Sbjct: 97  KDYYEVLDVKKDCTESDMKKAYRKLALQMHPDK 195

 Score = 37.0 bits (84), Expect(2) = 9e-10,   Method: Compositional matrix adjust.
 Identities = 20/60 (33%), Positives = 30/60 (50%), Gaps = 12/60 (20%)
 Frame = +3

Query: 431 VGEAFTILSDPKKKTRYDS-GQDLDEEGMNM---------GDFDANNIFKAFFGG--PGG 478
           +G A+++LSDP K+ +YD  G +L +   +          GD     +F  FFGG  P G
Sbjct: 231 IGNAYSVLSDPDKRRKYDVYGPELQQPSQHHSEYSNGGFEGDITPEELFNMFFGGGYPSG 410
>30337
          Length = 493

 Score = 59.7 bits (143), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 32/86 (37%), Positives = 47/86 (54%)
 Frame = -1

Query: 25  KREAESFKEQGNAYYAKKDYNEAYNYYTKAIDMCPNNASYYGNRAATLMMLGRFREALGD 84
           K  A   K QGN  +A + Y +A + YTKAI   PN A+Y+ NRA   + L  +  A  D
Sbjct: 340 KMSAIDLKNQGNKLFAARKYEDAIHCYTKAIMKNPNTATYFTNRALCYIKLRNWELASQD 161

Query: 85  AQQSVRLDDSFVRGHLREGKCHLSLG 110
            Q+++ LD + V+GH   G+  + L 
Sbjct: 160 CQRALELDRNLVKGHFFLGQALVELA 83

 Score = 50.1 bits (118), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 33/114 (28%), Positives = 52/114 (45%)
 Frame = -1

Query: 246 ACVACRNAKALKAKKEDGNKAFKEGNYKLAYELYTEALGIDPNNIKTNAKLYCNRGTVNS 305
           +CV  +   +    K  GNK F    Y+ A   YT+A+  +PN     A  + NR     
Sbjct: 361 SCVTPQRKMSAIDLKNQGNKLFAARKYEDAIHCYTKAIMKNPNT----ATYFTNRALCYI 194

Query: 306 KLRQLEDAIEDCTNAVKLDDTYIKAYLRRAQCYMDTEQFEEAVRDYEKVYQTEK 359
           KLR  E A +DC  A++LD   +K +    Q  ++   ++EA+    K +   K
Sbjct: 193 KLRNWELASQDCQRALELDRNLVKGHFFLGQALVELAMYDEAITHLMKAHDLAK 32
>35341
          Length = 641

 Score = 57.4 bits (137), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 32/83 (38%), Positives = 45/83 (54%)
 Frame = +3

Query: 283 LGIDPNNIKTNAKLYCNRGTVNSKLRQLEDAIEDCTNAVKLDDTYIKAYLRRAQCYMDTE 342
           + +DP    TNA L  NR     K+ +   A  DCT A+ LD  Y+KAYLRRA   +  +
Sbjct: 3   MDLDP----TNALLPANRAMALIKMEKYGVAEVDCTTAITLDPLYVKAYLRRAAARVGMQ 170

Query: 343 QFEEAVRDYEKVYQTEKTKEHKQ 365
           + + A+ DYE+V Q E   +  Q
Sbjct: 171 RLQPALEDYERVLQLEPNSKQAQ 239

 Score = 48.9 bits (115), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 29/112 (25%), Positives = 51/112 (45%)
 Frame = +3

Query: 55  IDMCPNNASYYGNRAATLMMLGRFREALGDAQQSVRLDDSFVRGHLREGKCHLSLGNAMA 114
           +D+ P NA    NRA  L+ + ++  A  D   ++ LD  +V+ +LR     + +     
Sbjct: 3   MDLDPTNALLPANRAMALIKMEKYGVAEVDCTTAITLDPLYVKAYLRRAAARVGMQRLQP 182

Query: 115 ACRSFQRALELDHKNAQAQQEFKNANAVMEYEKIAEVDFEKRDFRKVVFCMD 166
           A   ++R L+L+  + QAQ+E              E+D EK D R     ++
Sbjct: 183 ALEDYERVLQLEPNSKQAQKEVDRLR--------KELDREKEDARPTSTSLE 314
>01124
          Length = 1372

 Score = 57.0 bits (136), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 39/110 (35%), Positives = 55/110 (50%), Gaps = 8/110 (7%)
 Frame = -3

Query: 251 RNAKALKAKKEDGNKAFKEGNYKLAYELYTEALGIDPNNIKTNAKLYCNRGTVNSKLRQL 310
           RN + L+ K   GN  F  GNY+ A  +YT AL ++P        LY NR   + KLR L
Sbjct: 761 RNPQFLRDK---GNGFFASGNYQAAVNVYTHALRLNPK----MPSLYSNRAACHLKLRNL 603

Query: 311 EDAIEDCTNAVKLDD--------TYIKAYLRRAQCYMDTEQFEEAVRDYE 352
              IEDC+ A+ L          + +KA +RR   +   E + E ++DYE
Sbjct: 602 FKCIEDCSKAMDLLSPPVPQNAASRVKAMVRRGTAFCQLEMYVEGLQDYE 453

 Score = 48.1 bits (113), Expect = 8e-06,   Method: Compositional matrix adjust.
 Identities = 36/148 (24%), Positives = 69/148 (46%), Gaps = 8/148 (5%)
 Frame = -3

Query: 5   AECDVVMAATEPELLEDEDAKREAESFKEQGNAYYAKKDYNEAYNYYTKAIDMCPNNASY 64
           AE   +    + +L E+E   R  +  +++GN ++A  +Y  A N YT A+ + P   S 
Sbjct: 815 AEARQIADLADSDLTEEE---RNPQFLRDKGNGFFASGNYQAAVNVYTHALRLNPKMPSL 645

Query: 65  YGNRAATLMMLGRFREALGDAQQSVRLDD--------SFVRGHLREGKCHLSLGNAMAAC 116
           Y NRAA  + L    + + D  +++ L          S V+  +R G     L   +   
Sbjct: 644 YSNRAACHLKLRNLFKCIEDCSKAMDLLSPPVPQNAASRVKAMVRRGTAFCQLEMYVEGL 465

Query: 117 RSFQRALELDHKNAQAQQEFKNANAVME 144
           + ++ AL+LD  N Q +++ +    +++
Sbjct: 464 QDYEAALKLDPNNQQLKEDAEKMRQIIQ 381
>02324
          Length = 2058

 Score = 55.8 bits (133), Expect = 4e-08,   Method: Compositional matrix adjust.
 Identities = 35/100 (35%), Positives = 61/100 (61%), Gaps = 4/100 (4%)
 Frame = +2

Query: 377 SKRKDYYKILGVDKNASEDEIKKAYRKRALMHHPDRHSGASAEVQXXXXXXXXXVGEAFT 436
           SK + +Y++LGV+++A  D++KKAYRK AL  HPD++  +  E           V +A+ 
Sbjct: 92  SKIRCHYEVLGVERSADNDDLKKAYRKLALKFHPDKNPDSVEEA----TAQFRLVQQAYE 259

Query: 437 ILSDPKKKTRYDSGQD-LDEEGMNMGD-FDAN--NIFKAF 472
           IL+DP++++ YD  ++ +   G   GD ++ N  N+F+ F
Sbjct: 260 ILTDPQERSWYDRHREAILRGGQGKGDKYEDNSLNLFQYF 379
>26984
          Length = 1107

 Score = 54.7 bits (130), Expect = 8e-08,   Method: Compositional matrix adjust.
 Identities = 29/80 (36%), Positives = 46/80 (57%)
 Frame = -2

Query: 370 AQLELKKSKRKDYYKILGVDKNASEDEIKKAYRKRALMHHPDRHSGASAEVQXXXXXXXX 429
           A   L   K KD Y ILG+  +AS+++IK+ YR++A++ HPD++    AE          
Sbjct: 548 AMKRLLACKGKDPYSILGLRADASDEDIKRYYRRQAVLVHPDKNQEPGAE------EAFK 387

Query: 430 XVGEAFTILSDPKKKTRYDS 449
            +G AF ++ DP K+  YD+
Sbjct: 386 ILGHAFEMIGDPTKRKEYDT 327
>08670
          Length = 1307

 Score = 52.4 bits (124), Expect = 4e-07,   Method: Compositional matrix adjust.
 Identities = 30/103 (29%), Positives = 56/103 (54%)
 Frame = +3

Query: 35  GNAYYAKKDYNEAYNYYTKAIDMCPNNASYYGNRAATLMMLGRFREALGDAQQSVRLDDS 94
           GN     ++Y+ A   +T+AI + P +  + GNR+     L ++ +AL DA+++++L   
Sbjct: 393 GNEMAQVEEYSAAIQLFTEAIALDPKDFRFLGNRSYCYDRLQQYEKALKDAEKAIKLSKD 572

Query: 95  FVRGHLREGKCHLSLGNAMAACRSFQRALELDHKNAQAQQEFK 137
           + +G+ R+G+    L     A  SF + L+LD    +A QE +
Sbjct: 573 WPKGYFRKGRALAGLCKFSEAEESFLQVLKLDKNCEEAVQELQ 701

 Score = 46.2 bits (108), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 28/97 (28%), Positives = 49/97 (50%)
 Frame = +3

Query: 263 GNKAFKEGNYKLAYELYTEALGIDPNNIKTNAKLYCNRGTVNSKLRQLEDAIEDCTNAVK 322
           GN+  +   Y  A +L+TEA+ +DP +     +   NR     +L+Q E A++D   A+K
Sbjct: 393 GNEMAQVEEYSAAIQLFTEAIALDPKDF----RFLGNRSYCYDRLQQYEKALKDAEKAIK 560

Query: 323 LDDTYIKAYLRRAQCYMDTEQFEEAVRDYEKVYQTEK 359
           L   + K Y R+ +      +F EA   + +V + +K
Sbjct: 561 LSKDWPKGYFRKGRALAGLCKFSEAEESFLQVLKLDK 671

 Score = 29.3 bits (64), Expect = 3.7,   Method: Compositional matrix adjust.
 Identities = 18/60 (30%), Positives = 32/60 (53%)
 Frame = +3

Query: 300 RGTVNSKLRQLEDAIEDCTNAVKLDDTYIKAYLRRAQCYMDTEQFEEAVRDYEKVYQTEK 359
           RG   +++ +   AI+  T A+ LD    +    R+ CY   +Q+E+A++D EK  +  K
Sbjct: 390 RGNEMAQVEEYSAAIQLFTEAIALDPKDFRFLGNRSYCYDRLQQYEKALKDAEKAIKLSK 569
>14550
          Length = 1395

 Score = 51.6 bits (122), Expect = 6e-07,   Method: Compositional matrix adjust.
 Identities = 33/87 (37%), Positives = 47/87 (54%)
 Frame = -1

Query: 380  KDYYKILGVDKNASEDEIKKAYRKRALMHHPDRHSGASAEVQXXXXXXXXXVGEAFTILS 439
            +D+YKILGV K+A   +IK+AYRK A   HPD++       Q         +G A+ +LS
Sbjct: 1137 RDFYKILGVSKSADTKQIKRAYRKIAKELHPDKNRDDPEAEQ-----RFQDLGAAYEVLS 973

Query: 440  DPKKKTRYDSGQDLDEEGMNMGDFDAN 466
            D +K+  YD      EEG+  GD   +
Sbjct: 972  DEEKRKVYDR---HGEEGLKQGDMGGD 901
>02088
          Length = 1062

 Score = 51.2 bits (121), Expect = 8e-07,   Method: Compositional matrix adjust.
 Identities = 26/76 (34%), Positives = 42/76 (55%)
 Frame = +3

Query: 381 DYYKILGVDKNASEDEIKKAYRKRALMHHPDRHSGASAEVQXXXXXXXXXVGEAFTILSD 440
           D Y+++G+ + A+  E+KK Y K +L  HPD+ S A  E           +G+ +T+LSD
Sbjct: 108 DLYEVIGIRREATPQEVKKGYHKVSLAVHPDQVSAAEKET---ATRKFQTLGKVYTVLSD 278

Query: 441 PKKKTRYDSGQDLDEE 456
             K+  YD   ++ EE
Sbjct: 279 KDKRAXYDETGEVGEE 326
>23484
          Length = 1647

 Score = 48.1 bits (113), Expect = 7e-06,   Method: Compositional matrix adjust.
 Identities = 27/78 (34%), Positives = 39/78 (50%)
 Frame = +1

Query: 260 KEDGNKAFKEGNYKLAYELYTEALGIDPNNIKTNAKLYCNRGTVNSKLRQLEDAIEDCTN 319
           +E+GN  FK+ +Y+LA + Y E +  +      NA LY NR   +  L     A  DC  
Sbjct: 511 REEGNDLFKKKDYRLAVDNYXEGIKSNSPQRLQNAVLYTNRAAAHFHLGNYRSAFNDCFA 690

Query: 320 AVKLDDTYIKAYLRRAQC 337
           A K    ++KA +R A C
Sbjct: 691 ARKFKPDHLKALVRGAMC 744

 Score = 47.8 bits (112), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 31/90 (34%), Positives = 43/90 (47%), Gaps = 4/90 (4%)
 Frame = +1

Query: 20  EDEDAKREAESFKEQGNAYYAKKDYNEAYNYYTKAIDM-CP---NNASYYGNRAATLMML 75
           E ED    AES++E+GN  + KKDY  A + Y + I    P    NA  Y NRAA    L
Sbjct: 475 ESEDPVARAESYREEGNDLFKKKDYRLAVDNYXEGIKSNSPQRLQNAVLYTNRAAAHFHL 654

Query: 76  GRFREALGDAQQSVRLDDSFVRGHLREGKC 105
           G +R A  D   + +     ++  +R   C
Sbjct: 655 GNYRSAFNDCFAARKFKPDHLKALVRGAMC 744
>04645
          Length = 1075

 Score = 42.7 bits (99), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 34/133 (25%), Positives = 61/133 (45%), Gaps = 17/133 (12%)
 Frame = +3

Query: 266 AFKEGNYKLAYELYTEALGIDPNNIKTNAKLYCNRGTVNSKLRQLEDAIEDCTNAVKLDD 325
           A  EG  + A   +T+A+  +P    T+A LY  RG+   K+ + + AI DC+ A++L+ 
Sbjct: 474 AMAEGRLEDAIGFFTDAIKSNP----TSALLYAKRGSAYLKMGKPKKAIHDCSKAIELNP 641

Query: 326 TYIKAYLRRAQCYMDTEQFEEAVRD-----------------YEKVYQTEKTKEHKQLLK 368
              + Y  R + +     +EE+  D                 ++     +K  EHK+  +
Sbjct: 642 DSAQGYKWRGKAHKLLGHWEESYHDLTLACKLDYDDDANTALHDVTANAKKIMEHKRKYE 821

Query: 369 NAQLELKKSKRKD 381
             Q E + +KRK+
Sbjct: 822 RQQEERELTKRKE 860
>22505
          Length = 784

 Score = 40.4 bits (93), Expect(2) = 5e-04,   Method: Compositional matrix adjust.
 Identities = 19/32 (59%), Positives = 23/32 (71%)
 Frame = -1

Query: 381 DYYKILGVDKNASEDEIKKAYRKRALMHHPDR 412
           D Y ILGV   A+E +I KAYRK+AL  HPD+
Sbjct: 652 DLYGILGVGPEANEKQIVKAYRKKALKCHPDK 557

 Score = 20.8 bits (42), Expect(2) = 5e-04,   Method: Compositional matrix adjust.
 Identities = 7/18 (38%), Positives = 11/18 (61%)
 Frame = -3

Query: 431 VGEAFTILSDPKKKTRYD 448
           + +A  +L+DP  K  YD
Sbjct: 518 LSKALEVLTDPSAKAAYD 465
>00888
          Length = 970

 Score = 40.8 bits (94), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 33/114 (28%), Positives = 49/114 (42%), Gaps = 12/114 (10%)
 Frame = -3

Query: 257 KAKKEDGNKAFKEGNYKLA---YE-----LYTEALGIDPNNIKTNAKL----YCNRGTVN 304
           K  KE G  AFK+G Y+ A   YE     L  E+ G+  + +    +L    + N     
Sbjct: 737 KIIKEKGTAAFKKGKYQRALTNYEKIVSFLEHESTGLSDSELSDKHQLMVAAFLNIAMCQ 558

Query: 305 SKLRQLEDAIEDCTNAVKLDDTYIKAYLRRAQCYMDTEQFEEAVRDYEKVYQTE 358
            KL     A E C   + +    +KA  RR Q  ++   + EA  D+ KV + E
Sbjct: 557 LKLLDYRQAEETCNKVLAMSTNNVKALFRRGQARLECADYTEAASDFSKVLELE 396
>13560
          Length = 978

 Score = 37.0 bits (84), Expect = 0.017,   Method: Compositional matrix adjust.
 Identities = 34/140 (24%), Positives = 55/140 (39%), Gaps = 16/140 (11%)
 Frame = +1

Query: 257 KAKKEDGNKAFKEGNYKLAYELYTEA----LGIDP-----------NNIKTNAKLYCNRG 301
              KE G + FK GN   A+  +  A    L + P           ++++   + Y N  
Sbjct: 193 SVHKEKGAQYFKTGNIFAAFSHFRTAIRLLLSVLPYSFSDDEVASTSHLQLLCQCYLNLA 372

Query: 302 TVNSKLRQLEDAIEDCTNAVKLDDTYIKAYLRRAQCYMDTEQFEEAVRDYEKVYQTEK-T 360
               K    +  I +CT+A+ LD   +KA  RRA   ++      A  D E   Q E   
Sbjct: 373 ACQIKSGHHKHVITNCTHALNLDPANVKALYRRASANVNLGNLLHAHEDLETGLQKEPNN 552

Query: 361 KEHKQLLKNAQLELKKSKRK 380
           +    L++N    L  S+ +
Sbjct: 553 RALLDLMQNVNARLAPSQSQ 612
>20155
          Length = 484

 Score = 33.9 bits (76), Expect = 0.16,   Method: Compositional matrix adjust.
 Identities = 14/28 (50%), Positives = 22/28 (78%)
 Frame = +1

Query: 385 ILGVDKNASEDEIKKAYRKRALMHHPDR 412
           ILGV  +AS+ +IK A+++  L++HPDR
Sbjct: 151 ILGVSPSASKVKIKDAHKRIMLLNHPDR 234
>28154
          Length = 374

 Score = 33.9 bits (76), Expect = 0.17,   Method: Composition-based stats.
 Identities = 19/68 (27%), Positives = 33/68 (48%)
 Frame = +1

Query: 43  DYNEAYNYYTKAIDMCPNNASYYGNRAATLMMLGRFREALGDAQQSVRLDDSFVRGHLRE 102
           +YN+A + +  A+   P +A  +    ATL   GR  EA+     +++L   F+R     
Sbjct: 139 EYNKAVDCFQAALQARPKDALLWNKLGATLANGGRSEEAVDAYHNALQLSPGFIRSRYNL 318

Query: 103 GKCHLSLG 110
           G   ++LG
Sbjct: 319 GIACINLG 342
>03857
          Length = 1696

 Score = 33.5 bits (75), Expect = 0.18,   Method: Compositional matrix adjust.
 Identities = 25/92 (27%), Positives = 40/92 (43%)
 Frame = +1

Query: 67  NRAATLMMLGRFREALGDAQQSVRLDDSFVRGHLREGKCHLSLGNAMAACRSFQRALELD 126
           N AA  + L ++ EAL   Q+ +  D    +   R+G+ H    +   A  SFQ+AL  +
Sbjct: 637 NAAACCLKLNKYNEALEYCQEVLEADPDNSKAQYRQGQAHAGNKDYETALASFQKALAAN 816

Query: 127 HKNAQAQQEFKNANAVMEYEKIAEVDFEKRDF 158
             +   + E +     +E EK  E     R F
Sbjct: 817 PDDKGIKLEIQKVKRTVEEEKKREKQMYSRMF 912
>18150
          Length = 768

 Score = 26.2 bits (56), Expect(2) = 1.0,   Method: Compositional matrix adjust.
 Identities = 9/26 (34%), Positives = 19/26 (73%)
 Frame = +3

Query: 392 ASEDEIKKAYRKRALMHHPDRHSGAS 417
           A+ +E+  A+R+ + ++HPD+H  A+
Sbjct: 3   ATTEEVNNAFRRLSKIYHPDKHLEAA 80

 Score = 23.1 bits (48), Expect(2) = 1.0,   Method: Compositional matrix adjust.
 Identities = 13/30 (43%), Positives = 19/30 (63%), Gaps = 2/30 (6%)
 Frame = +2

Query: 433 EAFTILSDPKKKTRYDS--GQDLDEEGMNM 460
           EA  ILSD  K+T YD+   + L+ EG+ +
Sbjct: 119 EAHEILSDKHKRTIYDTYGEKGLETEGLEI 208
>33510
          Length = 501

 Score = 31.2 bits (69), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 31/106 (29%), Positives = 51/106 (48%), Gaps = 2/106 (1%)
 Frame = +3

Query: 309 QLEDAIEDC--TNAVKLDDTYIKAYLRRAQCYMDTEQFEEAVRDYEKVYQTEKTKEHKQL 366
           Q ED + +   ++A K D+    A +RR Q   D +  +  V ++ +     K K  + L
Sbjct: 54  QFEDLLGEANFSSASKKDEPKTIADMRRKQLEEDMDPDKLKVMEWTQ----GKEKNIRAL 221

Query: 367 LKNAQLELKKSKRKDYYKILGVDKNASEDEIKKAYRKRALMHHPDR 412
           L +    L  S+ +  +K  G+    S D++KK YRK  L  HPD+
Sbjct: 222 LCSLDKVLWDSESR--WKPCGMHDLVSADQVKKVYRKAVLSVHPDK 353
>22027
          Length = 692

 Score = 30.4 bits (67), Expect = 1.8,   Method: Compositional matrix adjust.
 Identities = 29/109 (26%), Positives = 47/109 (43%), Gaps = 9/109 (8%)
 Frame = -3

Query: 238 RMAPDHEKACVACRNAKALKAKKEDGNKAFKEGNYKLAYELYTEAL------GIDPNNIK 291
           ++AP+  +   +   A+AL+     GN+ FK G Y  A   Y  A+       +D N+  
Sbjct: 321 QIAPELSRQGKSVEQAEALRTT---GNEHFKCGKYDKALSCYNNAVRYAPHSTLDINSCN 151

Query: 292 TNAKLYCNRGTVNSKLRQLEDAIEDCTNAVK--LDDTYIKAYL-RRAQC 337
             A  + NR      L+Q    + D  NA++     T +   L RR +C
Sbjct: 150 VLALCFGNRSAAFFHLKQFHSCLADIDNALQAGFPATSLHKLLDRRGKC 4
>25094
          Length = 2323

 Score = 29.6 bits (65), Expect = 2.7,   Method: Compositional matrix adjust.
 Identities = 11/24 (45%), Positives = 18/24 (75%)
 Frame = +3

Query: 202 ILRMDSTNADALYVRGLCLYYEDC 225
           IL+M  T+ + L+V G+C+YY+ C
Sbjct: 222 ILQMLETSVEFLFVFGVCIYYK*C 293
>19619
          Length = 577

 Score = 29.6 bits (65), Expect = 3.1,   Method: Compositional matrix adjust.
 Identities = 21/92 (22%), Positives = 40/92 (43%), Gaps = 5/92 (5%)
 Frame = +3

Query: 156 RDFRKVVFCMDRALEFAPACHRFKILKAECLAMLGRYPEAQFVASDILRMDSTNADALYV 215
           + +++ +    +ALE  P      + +A+C   LG   EA    S+    +  +     +
Sbjct: 210 KQYQRAIESFTKALEMKPGDKTCLVARAKCFLNLGN-SEAALADSESALKNDEDGKGKDI 386

Query: 216 RGLC-----LYYEDCIEKAVQFFVQALRMAPD 242
           R LC     LY +   E A+ F+ +  +M P+
Sbjct: 387 RALCTKAEALYQKGDFETALVFYHRGHKMRPE 482
>10994
          Length = 2182

 Score = 29.3 bits (64), Expect = 3.5,   Method: Compositional matrix adjust.
 Identities = 12/42 (28%), Positives = 24/42 (57%)
 Frame = -3

Query: 312  DAIEDCTNAVKLDDTYIKAYLRRAQCYMDTEQFEEAVRDYEK 353
            +AI+    A+K+D  + +A + R   Y +   + +A+ D+EK
Sbjct: 1601 EAIQHLNLALKIDPLHTEALVARGAVYANNASYGKAIEDFEK 1476
>17683
          Length = 450

 Score = 28.9 bits (63), Expect = 5.2,   Method: Compositional matrix adjust.
 Identities = 11/26 (42%), Positives = 16/26 (61%)
 Frame = +2

Query: 387 GVDKNASEDEIKKAYRKRALMHHPDR 412
           GV  N    E+KK Y+K  + +HPD+
Sbjct: 365 GVSANPEWSEVKKLYQKAVIHYHPDK 442
>00150
          Length = 1809

 Score = 28.5 bits (62), Expect = 5.9,   Method: Compositional matrix adjust.
 Identities = 15/52 (28%), Positives = 27/52 (51%)
 Frame = -3

Query: 311  EDAIEDCTNAVKLDDTYIKAYLRRAQCYMDTEQFEEAVRDYEKVYQTEKTKE 362
            + ++E+C+ AVK     + A   RAQ   D     EA++D   + +T +T +
Sbjct: 1801 QQSLEECSXAVKAVPMNLIARKFRAQLLFDNHNVVEALKDLWVIPKTSRTPD 1646
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|13385998|ref|NP_080784.1| TNF receptor-associated
protein 1 [Mus musculus]
         (706 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

01628                                                                 189   3e-48
15623                                                                 164   2e-40
11278                                                                 161   9e-40
25874                                                                 157   2e-38
27487                                                                  51   2e-06
08006                                                                  30   2.6  
38554                                                                  29   5.2  
>01628
          Length = 2109

 Score =  189 bits (480), Expect = 3e-48,   Method: Compositional matrix adjust.
 Identities = 117/423 (27%), Positives = 227/423 (53%), Gaps = 11/423 (2%)
 Frame = -3

Query: 288  YLNGKRINTLQAIWMMDPKDISEFQHEEFYRYIAQAYDKPRFTLHYKTDAPLNIRSIFYV 347
            Y   + +N  + +W  +P DI+  ++ EFY+ +   ++      H+  +  L  R++ ++
Sbjct: 1969 YTEEEELNKTKPLWTRNPDDITAEEYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFI 1790

Query: 348  PEMKP-SMFDVSRELGSSVALYSRKVLIQTKAADILPKWLRFIRGVVDSEDIPLNLSREL 406
            P+  P  MF+  +   +++ LY R+V I     DI+P++L F++GVVDSED+PLN+SRE+
Sbjct: 1789 PKRAPFDMFENKK-KKNNIKLYVRRVFIMDNCEDIIPEYLNFVKGVVDSEDLPLNISREM 1613

Query: 407  LQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTTAEQDIKEDI 466
            LQ+S +++ +R  L ++ ++  ID   +D + Y KF+E +   ++ GI   +    ++ I
Sbjct: 1612 LQQSKILKVIRKNLVKKCME-LIDDLAEDKDNYNKFYEQFAKNLKLGIHEDSTN--RKKI 1442

Query: 467  AKLLRYESSALPAGQLTSLPDYASRMQAGTRNIYYLCAPNRHLAEHSPYYEAMKQKHTEV 526
            +  LRY SS   A ++ +  +Y SRM+   ++IYY+    R   ++S + E +K++  EV
Sbjct: 1441 SDFLRYHSSQ-SADEMVTFKEYVSRMKDNQKDIYYITGETREAVQNSAFVERVKKRGFEV 1265

Query: 527  LFCYEQFDELTLLHLREFDKKKLISVET---DIVVDHYKEEKFEDTSPADERLSEKETED 583
            L+  +  DE  +  L+E+D K L+ V     ++  D  +++KFE+        ++ E E 
Sbjct: 1264 LYMVDPIDEYCVQQLKEYDGKNLVCVTKEGLELPEDEAEKKKFEE--------AKAEFEG 1109

Query: 584  LMAWMRNALGSRVTNVKVTFRLDTHPAMVTVLEMGAARHFLRM---QQLAKTQEERAQLL 640
            L   M+  L  +V  V V+ RL + P  +   + G + +  R+   Q L  T        
Sbjct: 1108 LCKAMKEILDKKVEKVTVSQRLVSSPCCIVTSQYGWSANMERIMKAQALRDTSTMGYMAA 929

Query: 641  QPTLEINPRHTLIKKL---CQLRESEPELAQLLVDQIYENAMIAAGL-VDDPRAMVGRLN 696
            +   EINP H ++K L   C   +++  +  L +  ++E A++++G  ++DP +   R++
Sbjct: 928  KKHFEINPDHPIVKTLKVKCDADKNDKSVKDLCM-LLFETALLSSGFTLEDPTSHANRIH 752

Query: 697  DLL 699
             ++
Sbjct: 751  RMV 743
>15623
          Length = 2811

 Score =  164 bits (414), Expect = 2e-40,   Method: Compositional matrix adjust.
 Identities = 85/188 (45%), Positives = 133/188 (70%), Gaps = 5/188 (2%)
 Frame = -1

Query: 107 LYSEKEVFIRELISNASDALEKLRHKLVCEGQVL---PEMEIHLQTDAKKGTITIQDTGI 163
           L  ++E+F+RELISN+SDAL+K+R++ + +   L    ++ I +  D ++ T+TI+D+GI
Sbjct: 597 LLFQQEIFLRELISNSSDALDKIRYESLTDPSKLDAGKDLHIRIVPDKERKTLTIEDSGI 418

Query: 164 GMTQEELVSNLGTIARSGSKAFLEALQNQAETSSKIIGQFGVGFYSAFMVADKVEVYSRS 223
           GMT+ +LV+NLGTIA+SG+KAF+EALQ  A+ S  +IGQFGVGFYSA++VAD+V V S++
Sbjct: 417 GMTKADLVNNLGTIAKSGTKAFMEALQAGADIS--MIGQFGVGFYSAYLVADRVVVESKN 244

Query: 224 AAPESPGYQWLSDGSGVFEIAEASG--VRPGTKIIIHLKSDCKDFASESRVQDVVTKYSN 281
              E   Y W S   G F IA  +G  +  GT+I + +K D +++  E R+++V+ K+S 
Sbjct: 243 NDDEQ--YTWESSAGGSFTIAAPTGTPMGRGTRITLFMKEDQQEYLEERRIKEVIKKHSQ 70

Query: 282 FVSFPLYL 289
           F+ +P+ L
Sbjct: 69  FIGYPIKL 46
>11278
          Length = 988

 Score =  161 bits (407), Expect = 9e-40,   Method: Compositional matrix adjust.
 Identities = 93/232 (40%), Positives = 138/232 (59%), Gaps = 10/232 (4%)
 Frame = +1

Query: 68  KEEESLHS---IISNTEAVRGSVSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASD 124
           KEEE++      ++  + +R    K  FQAE  +++ ++  SLY  KE+F+RELISNASD
Sbjct: 190 KEEEAIKLDGLNVAQMKELREKSEKFAFQAEVNRMMKLIINSLYKNKEIFLRELISNASD 369

Query: 125 ALEKLRHKLVCEGQVL---PEMEIHLQTDAKKGTITIQDTGIGMTQEELVSNLGTIARSG 181
           AL+K+R   +    VL    E+ I ++ D +   + + DTGIGMT  +LV NLGTIA+SG
Sbjct: 370 ALDKIRFMSLTNKDVLHATDELSIKIKADTENHVLHVTDTGIGMTYNDLVKNLGTIAKSG 549

Query: 182 SKAFLEALQNQAETS-SKIIGQFGVGFYSAFMVADKVEVYSRSAAPESPGYQWLSDGSGV 240
           +  FL  +   + T  + +IGQFGVGFYS+F+VAD+V V S+    E   Y W SD    
Sbjct: 550 TSDFLAKMGEASPTELNDLIGQFGVGFYSSFLVADRVVVTSKHNDDEQ--YVWESDAES- 720

Query: 241 FEIAE---ASGVRPGTKIIIHLKSDCKDFASESRVQDVVTKYSNFVSFPLYL 289
           F +A+    + +  GT I +HLK +  DF     +  +V KYS F++F +Y+
Sbjct: 721 FSVAKDPRGNTLGRGTTISLHLKEEAHDFLEAGTLTSLVKKYSQFINFNIYM 876
>25874
          Length = 476

 Score =  157 bits (396), Expect = 2e-38,   Method: Compositional matrix adjust.
 Identities = 67/110 (60%), Positives = 86/110 (78%)
 Frame = +1

Query: 199 IIGQFGVGFYSAFMVADKVEVYSRSAAPESPGYQWLSDGSGVFEIAEASGVRPGTKIIIH 258
           +IGQFGVGFYS FMV D+V+V+++S  P SP  +W SDGSG +E++EA GV+ GTKI++H
Sbjct: 1   LIGQFGVGFYSTFMVGDRVDVFTKSHQPGSPALKWSSDGSGAYEVSEAEGVQRGTKIVVH 180

Query: 259 LKSDCKDFASESRVQDVVTKYSNFVSFPLYLNGKRINTLQAIWMMDPKDI 308
           LK D  DFA E  +  VV KYSNFV  P+YLNGKR+N +QA+WM DPKD+
Sbjct: 181 LKGDSYDFAKEEIITGVVKKYSNFVGVPIYLNGKRVNIVQALWMADPKDV 330
>27487
          Length = 377

 Score = 50.8 bits (120), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 28/101 (27%), Positives = 55/101 (54%)
 Frame = -3

Query: 434 KDAEKYAKFFEDYGLFMREGIVTTAEQDIKEDIAKLLRYESSALPAGQLTSLPDYASRMQ 493
           ++ + Y KF+E +   ++ GI        K  +  L+R+ +S     Q+ SL +Y +RM+
Sbjct: 294 ENNDDYKKFYEQFSKNLKLGIHEDTTNRTK--LVDLMRFHTSKSGEDQI-SLKEYIARMK 124

Query: 494 AGTRNIYYLCAPNRHLAEHSPYYEAMKQKHTEVLFCYEQFD 534
            G ++I+Y+   +R   + SP+ E +++K  EVL+  +  D
Sbjct: 123 EGQKDIFYITGESRAAVQASPFIEQLRKKGYEVLYLVDPID 1
>08006
          Length = 474

 Score = 30.4 bits (67), Expect = 2.6,   Method: Composition-based stats.
 Identities = 14/47 (29%), Positives = 26/47 (55%), Gaps = 3/47 (6%)
 Frame = +1

Query: 295 NTLQAIWMMDPKDISEFQHEEFYRYIAQAY---DKPRFTLHYKTDAP 338
           N + A++ M+P +++ F+H++  R I  A    ++P F  H    AP
Sbjct: 184 NNVLAVFGMEPLELASFRHKDTCRQIKMAQCW*NRPEFIRHVNNCAP 324
>38554
          Length = 703

 Score = 29.3 bits (64), Expect = 5.2,   Method: Composition-based stats.
 Identities = 13/26 (50%), Positives = 18/26 (69%)
 Frame = +2

Query: 268 SESRVQDVVTKYSNFVSFPLYLNGKR 293
           S S ++DV  KY NFV  PL ++GK+
Sbjct: 482 SGSFLRDVCAKYRNFVIVPLAVHGKK 559
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|29789383|ref|NP_742012.1| isoleucyl-tRNA synthetase
[Mus musculus]
         (1262 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

25686                                                                 190   3e-48
15076                                                                  37   0.063
11928                                                                  31   4.0  
10824                                                                  30   5.8  
>25686
          Length = 537

 Score =  190 bits (483), Expect = 3e-48,   Method: Composition-based stats.
 Identities = 92/173 (53%), Positives = 125/173 (72%), Gaps = 2/173 (1%)
 Frame = +1

Query: 900  VLGKRLKGAFKAVMMAIKRLSNEELERFQKSGSIVVEGHELHEEDIRLMYTFDQ--ATGG 957
            VLG +LKG FK V   I+ LS+ +L  F ++G+I V G +L  ED+R+M++  Q    G 
Sbjct: 1    VLGSKLKGQFKVVSEQIRGLSDAQLTTFIQTGTITVGGVDLQTEDLRVMFSVGQEKGQGE 180

Query: 958  TAQFEAHSDAQALVLLDVTPDQSMVDEGMAREVINRIQKLRKKCNLVPTDEITVYYNAKS 1017
              Q+EAHSD Q LVLLD+TPDQSM+DEG+AREVINR+Q+LRKK  L+P+DEI VYY A +
Sbjct: 181  VQQYEAHSDGQILVLLDITPDQSMLDEGVAREVINRVQRLRKKAKLLPSDEIVVYYQASA 360

Query: 1018 EGRYLNNVIESHTDFVFATIKAPLKPYPVPTSDNILIQEQTQLKGSELEITLT 1070
            +   L  +I+  +DF+ ATIK PLKPYPVP +DN++I +   +K  +LE+TLT
Sbjct: 361  D---LGRIIQQFSDFILATIKQPLKPYPVPPTDNVIIADTMPIKSHQLEMTLT 510
>15076
          Length = 2760

 Score = 36.6 bits (83), Expect = 0.063,   Method: Compositional matrix adjust.
 Identities = 44/182 (24%), Positives = 77/182 (42%), Gaps = 7/182 (3%)
 Frame = +2

Query: 456 AISRNRYWGTPIPLWVSEDLEEVVCIGSVAELEELSGTKISDLHRESIDHLTIPSRCGKA 515
           A+SR    GT +P W S+ L E +   +V     ++   ++ L +  +   + P      
Sbjct: 443 ALSRTYGLGTRLP-WDSQYLIESLSDSTVY----MAYYAVAHLLQGGVVDGSKPGPANIR 607

Query: 516 PLRRVSEVFDCWFESGSMPYAQVHYPFES----KREFEDAFPADFIAEGIDQTRGWFYTL 571
           P +   EV+D  F + +  Y +   P  +    + EF   +P D    G D  +      
Sbjct: 608 PEQLTLEVWDYIF-TQTDNYPKCDIPKSTLDLLRSEFSYWYPVDVRMSGKDLIQNHLTYF 784

Query: 572 LVLATALFGQPPFK---NVIVNGLILASDGQKMSKRKKNYPDPVSIIDKYGADALRLYLI 628
           +   TA++     K    +  NG IL  + +KMSK   N+      +DK+ AD +R  L 
Sbjct: 785 IYCHTAMWPNDKSKWPKGIRANGHILL-NSEKMSKSTGNFLTLYDAVDKFSADGMRFSLA 961

Query: 629 NS 630
           ++
Sbjct: 962 DA 967
>11928
          Length = 1623

 Score = 30.8 bits (68), Expect = 4.0,   Method: Composition-based stats.
 Identities = 18/59 (30%), Positives = 25/59 (42%)
 Frame = -3

Query: 180  PFSTACGTPLSNFESNQNYKDVQDPSVFVTFPLEEDENTSLVAWTTTPWTLPSNLALCV 238
            P ST  GTP  +   N            V  PLE + +T++  + T   T+    ALCV
Sbjct: 1204 PLSTVSGTPSVSVAGN------------VRLPLEREVSTTMTGYRTARLTITPRRALCV 1064
>10824
          Length = 1751

 Score = 30.0 bits (66), Expect = 5.8,   Method: Compositional matrix adjust.
 Identities = 13/40 (32%), Positives = 22/40 (55%)
 Frame = -3

Query: 435  WVPEFVREKRFGNWLKEARDWAISRNRYWGTPIPLWVSED 474
            W+PE  R++    W ++ +DW + + R WG    L + ED
Sbjct: 1503 WLPEASRQR----WQQQWKDWRMVQERGWGADAELVLDED 1396
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|85362742|ref|NP_001034227.1|
calcium/calmodulin-dependent protein kinase II gamma isoform 2 [Mus
musculus]
         (518 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

15910                                                                 189   3e-48
12721                                                                 122   4e-28
01392                                                                 121   7e-28
01707                                                                 111   8e-25
01060                                                                 102   2e-22
09606                                                                 101   9e-22
30755                                                                 100   1e-21
13592                                                                  99   3e-21
03240                                                                  99   6e-21
14420                                                                  97   2e-20
14126                                                                  96   4e-20
18484                                                                  95   6e-20
21079                                                                  95   6e-20
00300                                                                  92   5e-19
26711                                                                  90   2e-18
17975                                                                  85   7e-17
13212                                                                  84   1e-16
13066                                                                  82   6e-16
21433                                                                  68   2e-14
09007                                                                  76   3e-14
01966                                                                  73   3e-13
31885                                                                  71   8e-13
18921                                                                  70   1e-12
06405                                                                  70   2e-12
28638                                                                  61   3e-12
00486                                                                  69   4e-12
19761                                                                  69   6e-12
29581                                                                  68   9e-12
27405                                                                  67   2e-11
01718                                                                  65   6e-11
38560                                                                  65   7e-11
00392                                                                  65   8e-11
26560                                                                  65   8e-11
01756                                                                  64   1e-10
21808                                                                  63   2e-10
04591                                                                  63   4e-10
27546                                                                  62   8e-10
36002                                                                  60   1e-09
12786                                                                  60   2e-09
19301                                                                  60   3e-09
21418                                                                  60   3e-09
20152                                                                  59   4e-09
04138                                                                  57   1e-08
18663                                                                  57   2e-08
31120                                                                  55   6e-08
19094                                                                  54   2e-07
20655                                                                  54   2e-07
04852                                                                  53   4e-07
11185                                                                  52   8e-07
11780                                                                  50   1e-06
28157                                                                  50   2e-06
00715                                                                  50   2e-06
18481                                                                  50   2e-06
27274                                                                  50   2e-06
31489                                                                  50   3e-06
32000                                                                  50   3e-06
14116                                                                  49   5e-06
02638                                                                  49   5e-06
17722                                                                  47   1e-05
03508                                                                  46   3e-05
07940                                                                  46   5e-05
17300                                                                  46   5e-05
29590                                                                  45   8e-05
36481                                                                  45   9e-05
25019                                                                  44   1e-04
07291                                                                  44   2e-04
20773                                                                  43   2e-04
01106                                                                  42   5e-04
32957                                                                  42   9e-04
17644                                                                  41   0.001
18996                                                                  40   0.002
00394                                                                  40   0.002
15549                                                                  40   0.002
31789                                                                  40   0.003
12672                                                                  39   0.006
11404                                                                  38   0.008
18287                                                                  37   0.023
18401                                                                  36   0.029
07836                                                                  36   0.030
37063                                                                  36   0.038
21800                                                                  36   0.042
26009                                                                  36   0.044
20559                                                                  35   0.049
23319                                                                  35   0.063
20513                                                                  34   0.17 
37602                                                                  33   0.20 
29360                                                                  33   0.23 
32359                                                                  33   0.23 
22005                                                                  33   0.24 
17516                                                                  33   0.24 
16350                                                                  33   0.25 
03106                                                                  33   0.26 
16708                                                                  33   0.37 
13305                                                                  32   0.65 
14104                                                                  32   0.74 
03294                                                                  30   1.9  
17011                                                                  30   2.1  
33586                                                                  30   3.3  
12704                                                                  30   3.3  
35032                                                                  29   5.2  
31232                                                                  28   8.3  
05487                                                                  28   9.8  
00638                                                                  28   10.0 
>15910
          Length = 1361

 Score =  189 bits (479), Expect = 3e-48,   Method: Compositional matrix adjust.
 Identities = 95/216 (43%), Positives = 139/216 (64%)
 Frame = +2

Query: 97  ELFEDIVAREYYSEADASHCIHQILESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLA 156
           ELF+ IV R  Y+E DA+  I  IL  V +IH + +VHRDLKPENLL       + +KLA
Sbjct: 422 ELFDRIVTRGQYTEKDAARAISDILHGVQYIHANGVVHRDLKPENLLYECMTDDSKLKLA 601

Query: 157 DFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWD 216
           DFGL+  ++ E Q      GTPGY +PEVL+ D Y   VD+W+ GVI YILL GY PF+ 
Sbjct: 602 DFGLSRIIEPEVQM-STVCGTPGYCAPEVLKGDKYTPSVDMWSVGVIAYILLCGYEPFFA 778

Query: 217 EDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITADQALKHPWVCQRS 276
           E++ ++Y++I  G Y F    W  ++  AK+++ ++L I+P KR+TA +AL+ PWV   +
Sbjct: 779 ENEFEMYRKIIKGEYKFDEEYWSEISENAKDVVRKLLVIDPKKRLTATEALRLPWVKGVA 958

Query: 277 TVASMMHRQETVECLRKFNARRKLKGAILTTMLVSR 312
           T  + M  + T+  L++FNARRKLK A    +++++
Sbjct: 959 TKTTNM--EITMNKLKEFNARRKLKCATDAMLVIAK 1060
>12721
          Length = 821

 Score =  122 bits (306), Expect = 4e-28,   Method: Compositional matrix adjust.
 Identities = 77/260 (29%), Positives = 134/260 (51%), Gaps = 6/260 (2%)
 Frame = +1

Query: 10  FTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLE---REARICR 66
           F DD   F ++G+G+  +V  C+  +      A     KK+  R  Q+ E    E  + R
Sbjct: 91  FLDD---FMKIGEGSTGIV--CIATSRDGRQMA----VKKMDLRKQQRRELLFNEVVVMR 243

Query: 67  LLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESVNH 126
              HPNIV +++S       ++V + + GG L  DIV      E   +      L+++  
Sbjct: 244 DYHHPNIVEMYNSYLVNDELWVVMEFMEGGAL-TDIVTNNRMDEVQIATVCRACLKALAF 420

Query: 127 IHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVL 186
           +H + ++HRD+K +++LL+   K   VKL DFG   +V  + Q      GTP +++PEV+
Sbjct: 421 LHANGVIHRDIKSDSILLSHDGK---VKLXDFGFCAQVTQDLQKRKSLVGTPYWMAPEVI 591

Query: 187 RKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT---VTP 243
            + PYG  VDIW+ G+++  ++   PPF++E   +  ++I+    D P P+      ++P
Sbjct: 592 SRLPYGPEVDIWSLGIMVMEMIDAEPPFFNEPPLQAMRRIR----DMPPPKLRNTHKISP 759

Query: 244 EAKNLINQMLTINPAKRITA 263
             +  I++ML  +P +R TA
Sbjct: 760 RLQGFIDRMLVRDPHQRATA 819
>01392
          Length = 1806

 Score =  121 bits (303), Expect = 7e-28,   Method: Compositional matrix adjust.
 Identities = 76/231 (32%), Positives = 112/231 (48%), Gaps = 25/231 (10%)
 Frame = -1

Query: 107  YYSEADASHCIHQILESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLA--IEV 164
            +  E +AS  +  I  +++ +H   I HRDLKPEN+L         VK+ DF LA  I  
Sbjct: 1803 HLCEREASLVVRHIARALDFLHSKGIAHRDLKPENILCEHLDDVVPVKICDFDLASGISC 1624

Query: 165  QGEQQA---WFGFAGTPGYLSPEVLR-----KDPYGKPVDIWACGVILYILLVGYPPFWD 216
             G+           G+  Y++PEV+         Y K  D+W+ G+ILYI+L GYPPF+ 
Sbjct: 1623 DGDGTKTPELLTPVGSAEYMAPEVVDAWVGDSFSYDKRCDLWSLGIILYIMLCGYPPFYG 1444

Query: 217  ---ED------------QHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRI 261
               ED            Q  L+  I+ G Y FPS EW +++  AK+LI  +L   P KR 
Sbjct: 1443 QCGEDCGWNRGEACHDCQDMLFNSIQDGHYKFPSQEWTSISSSAKDLIRHLLVREPRKRY 1264

Query: 262  TADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKLKGAILTTMLVSR 312
            +A   LKHPW+C       +     T   L + N+ + L+    T + ++R
Sbjct: 1263 SAADVLKHPWICTPPAATQL----ATPHVLTRNNSMKDLENFAETAISINR 1123
>01707
          Length = 757

 Score =  111 bits (277), Expect = 8e-25,   Method: Compositional matrix adjust.
 Identities = 74/218 (33%), Positives = 111/218 (50%), Gaps = 4/218 (1%)
 Frame = +1

Query: 12  DDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREARICRLLKHP 71
           + Y+   ++G+G++ VV +C  K ++Q  A K     +      +   RE R+ + LKHP
Sbjct: 64  EKYEKIGKIGEGSYGVVFKCRNKETSQLVAIKKFVESEDDPLIKKIAMREIRMLKQLKHP 243

Query: 72  NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESVNHIHQHD 131
           N+VRL +    +   +LVFD V    L E         E      I+Q L +VN  HQ++
Sbjct: 244 NLVRLIEVFRRKKRLHLVFDYVDHTLLNELDRYPRGLPEPMVKRIIYQTLLAVNFCHQYN 423

Query: 132 IVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKDP- 190
            +HRD+KPEN+L+  +     VKL DFG A  + G    +  +  T  Y +PE+L  D  
Sbjct: 424 TIHRDVKPENILITRQ---GQVKLCDFGFARILTGPGDEYTDYVATRWYRAPELLVGDTQ 594

Query: 191 YGKPVDIWACGVILYILLVG---YPPFWDEDQHKLYQQ 225
           YG PVD+WA G +   LL G   +P   D DQ  L ++
Sbjct: 595 YGPPVDVWAIGCVFAELLTGQALWPGRSDVDQLHLIRK 708
>01060
          Length = 1800

 Score =  102 bits (255), Expect = 2e-22,   Method: Compositional matrix adjust.
 Identities = 83/302 (27%), Positives = 138/302 (45%), Gaps = 37/302 (12%)
 Frame = +1

Query: 13  DYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREARICRLLKHPN 72
           D   F+++G+G + VV +C  + + ++ A K I  +           RE  + R L+H N
Sbjct: 76  DLTDFQKIGEGTYGVVYKCRHRATGRKLAMKKIRLRGSEDGVPSSAIREIAMLRELRHTN 255

Query: 73  IVRLHDSISEEGFHYLVFDLVTG-----------GELFEDIVAREYYSEADASHCIHQIL 121
           IV L D I E+   +LVF+ ++            G + +  + + Y         + QI+
Sbjct: 256 IVCLEDVIMEDERLFLVFEFLSMDLKMYIDKFPEGVVLDRRLVKSY---------VFQIV 408

Query: 122 ESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYL 181
             +   HQ  IVHRDLKP+NLL+       A+K+ADFG+A       +A+     T  Y 
Sbjct: 409 TGIXFCHQRRIVHRDLKPQNLLINHT---GAIKIADFGMARTFALPVRAYTHEVVTLWYR 579

Query: 182 SPEVLR-KDPYGKPVDIWACGVILYILLVGYPPFWDEDQ----HKLYQQI---------- 226
           +PE+L     Y  PVD+W+ G I   +L+  P F  + +     K+++ I          
Sbjct: 580 APEILMGASKYSTPVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIFRIIGTPTEQTWPE 759

Query: 227 --KAGAYDFPSPEW------DTVT---PEAKNLINQMLTINPAKRITADQALKHPWVCQR 275
             K  A++   P W      +T+T       +LI + L  +PA+RI+  + L+H +    
Sbjct: 760 FHKLPAFNGMFPLWKEGKLSETLTDLDSLGLDLIERTLKCDPAQRISCKKMLQHAYFLNV 939

Query: 276 ST 277
            T
Sbjct: 940 DT 945
>09606
          Length = 1300

 Score =  101 bits (251), Expect = 9e-22,   Method: Compositional matrix adjust.
 Identities = 74/286 (25%), Positives = 134/286 (46%), Gaps = 28/286 (9%)
 Frame = -3

Query: 12   DDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREARICRLLKHP 71
            +++ L+EELGKG  S++ +  +K +    A   I   K       ++    R+   + HP
Sbjct: 1115 ENFVLYEELGKGEHSIIYKGRRKGTINFVAIHCIEKCK-----RPEVTNTVRMTHDISHP 951

Query: 72   NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYY-SEADASHCIHQILESVNHIHQH 130
            N+V+ H+        +LV +L TGG L  DI+A++++  E         ++  +++IH  
Sbjct: 950  NVVQFHEWYETSNHLWLVVELCTGGSL-ADILAQDHHLPETSIRDFGIHLVTGLHYIHSL 774

Query: 131  DIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGE--QQAWFGFA------------- 175
             I+  DL+P  +LL +      +K ADFGL+ +V+GE  ++ +F FA             
Sbjct: 773  GILFHDLRPSKVLLDTS---GVLKFADFGLS-KVEGENLEELFFKFAEAGDQWNIQSAEE 606

Query: 176  --------GTPGYLSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIK 227
                    G+P Y++PEV +        D+WA G + Y +  G+PPF  E       ++ 
Sbjct: 605  MMKQVPTSGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFSGHPPFLGETYDITKDKVL 426

Query: 228  AGAYDFPSPEWDTV----TPEAKNLINQMLTINPAKRITADQALKH 269
               +  P  +   +    +PE  NL+  +L  +  +R++    +KH
Sbjct: 425  NKEFPLPKVKGSRLSAKPSPEFLNLLESLLQKDSTRRLSWASLVKH 288
>30755
          Length = 1137

 Score =  100 bits (250), Expect = 1e-21,   Method: Compositional matrix adjust.
 Identities = 55/147 (37%), Positives = 83/147 (56%)
 Frame = +2

Query: 119 QILESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTP 178
           +I+ ++ ++H   I++RDLK ENLLL    K   +K+ADFGL  E     +    F GTP
Sbjct: 56  EIISALGYLHSQGIIYRDLKLENLLLD---KDGHIKVADFGLCKEDITYGRTTKTFCGTP 226

Query: 179 GYLSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEW 238
            YL+PEVL  + YG+ VD W  GV++Y ++ G  PF++ D   L+  I      FP    
Sbjct: 227 EYLAPEVLDDNDYGRAVDWWGTGVVMYEMICGRLPFYNRDHDVLFTLILVEDVKFPR--- 397

Query: 239 DTVTPEAKNLINQMLTINPAKRITADQ 265
             +T EAK+L++ +L  +P  R+   Q
Sbjct: 398 -NITDEAKSLLSGLLAKDPRNRLGGGQ 475
>13592
          Length = 980

 Score = 99.4 bits (246), Expect = 3e-21,   Method: Compositional matrix adjust.
 Identities = 76/264 (28%), Positives = 127/264 (48%), Gaps = 11/264 (4%)
 Frame = +2

Query: 19  ELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHD 78
           ++G+G F  V   V   + +  A K I  +    R  + +  E +I   +KH N+VR + 
Sbjct: 5   KIGQGRFGKVYTAVNNNTGELMAMKEIAIQPGETRALKNVAEELKILEGIKHKNLVRYY- 181

Query: 79  SISEEGFHYLVF-DLVTGGELFEDIVAREYYSEADASHCIHQILESVNHIHQHDIVHRDL 137
            I       L+F +L + G L   +       EA +     Q+L  V  +H+H IVHRD+
Sbjct: 182 GIEVHREELLIFMELCSEGTLESLVELTGGLPEALSRRFTAQLLSGVAELHKHGIVHRDI 361

Query: 138 KPENLLLASKCKGAAVKLADFGLAIEVQ------GEQQAWFGFAGTPGYLSPEVLRK--- 188
           K  N+ L       ++KL DFG A+++Q      GE Q   G+ GT  Y++PEV  K   
Sbjct: 362 KTANIFLVDGSN--SLKLGDFGSAVKIQAHTTVPGELQ---GYVGTQAYMAPEVFTKTNS 526

Query: 189 DPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFP-SPEWDTVTPEAKN 247
           D +G+  DIW+ G ++  +  G  P W +         K G  + P +PE  +++ E  +
Sbjct: 527 DGHGRLADIWSVGCVVVEMASGKRP-WAQFDSNFQIMFKVGMGEKPQAPE--SLSQEGHD 697

Query: 248 LINQMLTINPAKRITADQALKHPW 271
            I+  L  +P +R++A + L+  +
Sbjct: 698 FIDHCLQHDPKQRLSAIELLEQNF 769
>03240
          Length = 1683

 Score = 98.6 bits (244), Expect = 6e-21,   Method: Compositional matrix adjust.
 Identities = 68/250 (27%), Positives = 112/250 (44%), Gaps = 48/250 (19%)
 Frame = -3

Query: 14   YQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARD---HQKLEREARICRLLKH 70
            ++  + LG GAF  V  C K  +   YA K +    +  R+   H K ER+  I     +
Sbjct: 1285 FEKIKTLGVGAFGEVSLCRKNDTGMLYAMKTLRKSDVLKRNQVAHVKAERD--ILAEADN 1112

Query: 71   PNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESVNHIHQH 130
              +V+L+ S  +  + Y V D V GG+L   ++  E   E  A   + ++++++  +H+ 
Sbjct: 1111 EWVVKLYYSFQDHNYLYFVMDYVPGGDLMGLLIRMEILDEPLARFYVAELVQAIESVHRM 932

Query: 131  DIVHRDLKPENLLLASKCKGAAVKLADFGLA-------------------------IEVQ 165
              +HRD+KP+N+L+    +   +KL DFGL                          ++ Q
Sbjct: 931  GFIHRDIKPDNILID---RNGHIKLTDFGLCTGFRWTHNSKYYQRDGTHARQDSMEVKCQ 761

Query: 166  GEQQAW-------------------FGFAGTPGYLSPEVL-RKDPYGKPVDIWACGVILY 205
             ++Q                         GTP Y++PEVL R   Y    D W+ GVIL+
Sbjct: 760  LDEQCQCEILKPLERRRKREQRCLAHSLVGTPNYIAPEVLSRLGGYTSVCDWWSVGVILF 581

Query: 206  ILLVGYPPFW 215
             +LVG+PPF+
Sbjct: 580  EMLVGHPPFY 551
>14420
          Length = 528

 Score = 97.1 bits (240), Expect = 2e-20,   Method: Compositional matrix adjust.
 Identities = 56/175 (32%), Positives = 96/175 (54%), Gaps = 3/175 (1%)
 Frame = +2

Query: 47  TKKLSARDHQKLE-REARICRLLKHPNIVRLHDS--ISEEGFHYLVFDLVTGGELFEDIV 103
           T  LS +  ++L   E  + R  ++PNIV   DS  + EE   ++V + + GG L  D+V
Sbjct: 5   TMNLSQQPKKELIINEILVMRENQNPNIVNYLDSYLVGEE--LWVVMEFLAGGSL-TDVV 175

Query: 104 AREYYSEADASHCIHQILESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIE 163
                 E   +    + L+++  +H++ ++HRD+K +N+LL       +VKL DFG   +
Sbjct: 176 TETCMDEGQIAAVCRECLQALEFLHENQVIHRDIKSDNILLGMD---GSVKLTDFGFCAQ 346

Query: 164 VQGEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDED 218
           +  EQ       GTP +++PEV+ +  YG  VDIW+ GV+   ++ G PP+ +E+
Sbjct: 347 LSPEQSKRSTMVGTPYWMAPEVVTRKQYGPTVDIWSLGVMCIEMIEGEPPYLNEN 511
>14126
          Length = 1265

 Score = 95.9 bits (237), Expect = 4e-20,   Method: Compositional matrix adjust.
 Identities = 90/311 (28%), Positives = 135/311 (43%), Gaps = 53/311 (17%)
 Frame = +3

Query: 15  QLFEE---LGKGAFSVVRRCVKKTSTQEYAA-KIINTKKLSARDHQKLEREARICRLLK- 69
           Q +EE   +G GA+  V +     +  E+ A K I              RE  + + L+ 
Sbjct: 189 QKYEEVAVIGNGAYGTVYKARDLRNQGEFVAMKRIRLNNTEEGMPMMAIREISMLKQLEQ 368

Query: 70  --HPNIVRL----HDSISEEG------FHYLVFDLVT----------GGELFEDIVAREY 107
             HPN+VRL    H++I++        F Y+  DL T          G +  +D++    
Sbjct: 369 YEHPNVVRLLDVSHNTITDREIRLNLVFEYIEHDLATYLAKCPSPGLGPDRIKDLML--- 539

Query: 108 YSEADASHCIHQILESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGE 167
                      Q+L  V+ +H + IVHRDLKP+NLL++   K   +KLADFGLA  +   
Sbjct: 540 -----------QLLNGVDFLHSNRIVHRDLKPQNLLIS---KDGRLKLADFGLA-RIYSF 674

Query: 168 QQAWFGFAGTPGYLSPEVLRKDPYGKPVDIWACGVILYIL-------------------- 207
             A      T  Y SPEVL +  YG  VDIW+CG I   L                    
Sbjct: 675 HMALTTVVVTLWYRSPEVLMQAEYGTSVDIWSCGCIFAELFTRRALFKGSSEFDQLKKIF 854

Query: 208 -LVGYPPF--WDED---QHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRI 261
            ++G PP   W E        ++           PE D   P+AK+L+ +ML     +RI
Sbjct: 855 EVIGLPPAGDWPEGVSVHRNSFRPTPPVPLQTLVPEMD---PQAKDLMEKMLVFKSGRRI 1025

Query: 262 TADQALKHPWV 272
           ++ ++L HP++
Sbjct: 1026SSRESLLHPYL 1058
>18484
          Length = 635

 Score = 95.1 bits (235), Expect = 6e-20,   Method: Compositional matrix adjust.
 Identities = 53/154 (34%), Positives = 83/154 (53%)
 Frame = +1

Query: 108 YSEADASHCIHQILESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGE 167
           + E  A+    +I   +  +H   I++RDLK +N++L S+     +K+ADFG+  E    
Sbjct: 34  FKEPVAAFYAAEIAVGLFFLHDQGIIYRDLKLDNVMLDSE---GHIKIADFGMCKEGMTG 204

Query: 168 QQAWFGFAGTPGYLSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIK 227
                 F GTP Y++PE++   PY K VD WA GV+L+ +L G PPF  ED+ +L+  I 
Sbjct: 205 DATTRTFCGTPDYIAPEIVLYQPYSKSVDWWAYGVLLFEMLAGQPPFDGEDEDELFSSIT 384

Query: 228 AGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRI 261
                +P      ++ EA +L   +L  NP KR+
Sbjct: 385 DHNVSYPK----AMSREAVSLCKGLLMKNPTKRL 474
>21079
          Length = 878

 Score = 95.1 bits (235), Expect = 6e-20,   Method: Compositional matrix adjust.
 Identities = 54/145 (37%), Positives = 77/145 (53%), Gaps = 1/145 (0%)
 Frame = +1

Query: 70  HPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREY-YSEADASHCIHQILESVNHIH 128
           HP ++ L D+        LV + V  GELFE ++  ++  +E D  H + QI   V ++H
Sbjct: 1   HPKLLMLWDAFEAPRTMVLVMEFVGAGELFERVIRDDFVLTERDCVHFVRQICSGVGYMH 180

Query: 129 QHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRK 188
              I+H DLKPEN+L  S      +K+ DFGLA   +        F GTP +++PEV+  
Sbjct: 181 TQSILHLDLKPENVLCVSD-NSNQIKIIDFGLARFYKPGDSLQVLF-GTPEFIAPEVVNY 354

Query: 189 DPYGKPVDIWACGVILYILLVGYPP 213
           D      D+W+ GVI YILL G  P
Sbjct: 355 DEINFTTDMWSIGVICYILLSGLSP 429
>00300
          Length = 2318

 Score = 92.0 bits (227), Expect = 5e-19,   Method: Compositional matrix adjust.
 Identities = 73/273 (26%), Positives = 131/273 (47%), Gaps = 10/273 (3%)
 Frame = -1

Query: 9    RFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER---EARIC 65
            R    +Q   ++G+G F  V   V  ++ +  A K +   K    D Q+L     E +I 
Sbjct: 1667 RVNFRWQRGNKIGEGQFGKVYTAVNMSTGELMALKEM---KFQPNDLQQLREMCDEIKIF 1497

Query: 66   RLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESVN 125
              ++H N+V+ +     +    +  +    G + E   A+    E        +I+ +VN
Sbjct: 1496 EGIQHENLVKYYGVEVHKDEMLMFMEYCDTGTIEE--AAKMGLPEYLIRRYTREIVLAVN 1323

Query: 126  HIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQA---WFGFAGTPGYLS 182
            H+H++ IVHRD+K  N+ L S      VKL DFG +++++        +    GT  Y++
Sbjct: 1322 HLHENSIVHRDIKGANIFLTSN---GHVKLGDFGCSVKLKSHTTMPGEFHNLVGTTAYMA 1152

Query: 183  PEVLRKDP---YGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQI-KAGAYDFPSPEW 238
            PEV  ++    YG+  DIW+ G ++  +  G  P+ D D +  YQ + K G    P+   
Sbjct: 1151 PEVFTQNDQGGYGRAADIWSLGCVVIEMATGKRPWHDLDNN--YQIMYKVGIGHKPAVP- 981

Query: 239  DTVTPEAKNLINQMLTINPAKRITADQALKHPW 271
            D+++ E K+ ++ ++  +PA+R  A Q L H +
Sbjct: 980  DSLSVEGKHFLDLIMCHDPAQRALASQLLDHTF 882
>26711
          Length = 405

 Score = 89.7 bits (221), Expect = 2e-18,   Method: Composition-based stats.
 Identities = 48/134 (35%), Positives = 75/134 (55%), Gaps = 1/134 (0%)
 Frame = -2

Query: 117 IHQILESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAG 176
           + Q+L+ + H+H   +VH DLKP NLLL+   K  +V+L DFGLA ++   Q+ +    G
Sbjct: 398 VKQVLDILQHVHAQGVVHMDLKPSNLLLSGD-KLDSVQLIDFGLARKLYPPQETFLNH-G 225

Query: 177 TPGYLSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFP-S 235
           TPG+ SPE L   P     D+W  GV+ YILL G  PF  +   +  ++ +   + F   
Sbjct: 224 TPGFTSPEALDVKPISTASDVWGVGVLAYILLSGQSPFQADSATESLKKTQTCDWSFDVC 45

Query: 236 PEWDTVTPEAKNLI 249
           P +  ++ +AK+ I
Sbjct: 44  PSFSNMSQDAKDFI 3
>17975
          Length = 449

 Score = 85.1 bits (209), Expect = 7e-17,   Method: Composition-based stats.
 Identities = 47/138 (34%), Positives = 79/138 (57%), Gaps = 1/138 (0%)
 Frame = +3

Query: 25  FSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEG 84
           F+VV+      + ++ A K+I+  KL       L +E R  +L++HPN+VRL++ I  + 
Sbjct: 6   FAVVKLARHVFTGEKVAVKVIDKTKLDEVSRSHLFQEVRCMKLVQHPNVVRLYEVIDTQT 185

Query: 85  FHYLVFDLVTGGELFEDIVARE-YYSEADASHCIHQILESVNHIHQHDIVHRDLKPENLL 143
             YL+ +L  GG++++ I+       E  A     QI+E++++ H+  +VHRDLKPEN++
Sbjct: 186 KLYLILELGDGGDMYDYIMRHSGGLEEKLAKRYFRQIVEAISYCHKLHVVHRDLKPENVV 365

Query: 144 LASKCKGAAVKLADFGLA 161
                K   VKL DFG +
Sbjct: 366 FFE--KPGLVKLTDFGFS 413
>13212
          Length = 1067

 Score = 84.0 bits (206), Expect = 1e-16,   Method: Compositional matrix adjust.
 Identities = 64/199 (32%), Positives = 103/199 (51%), Gaps = 10/199 (5%)
 Frame = -1

Query: 89   VFDLVTGGELFEDIVAREY-YSEADASHCIHQILESVNHIHQHDIVHRDLKPENLLLASK 147
            VF ++  G L   +V  E   +EA   +  H++  +++ +H+H ++HRD+K  N+LL   
Sbjct: 1049 VFRVLWWGALDSIMVDLEKPMTEAQICYVCHEMCMALDFLHRHHVIHRDIKAGNVLLTI- 873

Query: 148  CKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEV-----LRKDPYGKPVDIWACGV 202
                 VKLADFG++ +    QQ    F GTP +++PEV     L+  PY    DIW+ GV
Sbjct: 872  --DGEVKLADFGVSAKNTQTQQKRDTFIGTPYWMAPEVVLCETLKDTPYDFKADIWSLGV 699

Query: 203  ILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPE----WDTVTPEAKNLINQMLTINPA 258
             L       PP  +++ H +   IK    D P+ E    W  +    K+ I + L  +P 
Sbjct: 698  TLIEFAQIEPP--NKEMHPMRVLIKIHKSDPPTLEKPKKWTKL---FKDFIAKCLVKDPN 534

Query: 259  KRITADQALKHPWVCQRST 277
             R TA + L+HP++ +R+T
Sbjct: 533  LRPTAAELLEHPFM-KRAT 480
>13066
          Length = 551

 Score = 82.0 bits (201), Expect = 6e-16,   Method: Compositional matrix adjust.
 Identities = 53/166 (31%), Positives = 83/166 (50%), Gaps = 5/166 (3%)
 Frame = +3

Query: 41  AAKIINTKKLSARDHQKL-EREARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELF 99
           A KII+ +K      +K   RE  +   L HP I+++H  +     +++       G+L 
Sbjct: 63  ACKIIDKEKAPVDFVEKFFPRELDLLTKLDHPYIIQIHSILQRXPKNFIFMRFAERGDLL 242

Query: 100 EDIVAREYYSEADASHCIHQILESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFG 159
             I    +  E  A    +Q+  ++N++H +D+ HRDLK EN+LL+S      VKLADFG
Sbjct: 243 TYIQEVGFVKEKQAKIWFYQMTTALNYLHSYDVAHRDLKCENILLSSHFN---VKLADFG 413

Query: 160 LA---IEVQGEQQAWFGFAGTPGYLSPEVLRKDPYG-KPVDIWACG 201
            A   I   GE+     + G+  Y +PE++   PY  K  D W+ G
Sbjct: 414 FACACITESGEKYMSRTYCGSAAYAAPEIVYGAPYAPKVADAWSLG 551
>21433
          Length = 590

 Score = 67.8 bits (164), Expect(2) = 2e-14,   Method: Compositional matrix adjust.
 Identities = 46/142 (32%), Positives = 74/142 (52%), Gaps = 5/142 (3%)
 Frame = +2

Query: 117 IHQILESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAG 176
           I+Q+  ++ + H   ++HRD+KPENLLL  K     +K+ADFG ++     ++      G
Sbjct: 185 IYQLSSALEYCHYRKVIHRDIKPENLLLGLK---GDLKIADFGWSVHAPSSRRT--TMCG 349

Query: 177 TPGYLSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSP 236
           T  YL PE++    + + VD+W+ GV+ Y  LVG PP          +          SP
Sbjct: 350 TLDYLPPEMVEGKTHDENVDLWSLGVLCYEFLVGTPPL---------RPSPTRPPTPASP 502

Query: 237 EWDT-----VTPEAKNLINQML 253
            W +     VTP A++LI+++L
Sbjct: 503 RWTSGSPSIVTPGARDLISKLL 568

 Score = 29.3 bits (64), Expect(2) = 2e-14,   Method: Compositional matrix adjust.
 Identities = 14/47 (29%), Positives = 26/47 (55%)
 Frame = +3

Query: 56  QKLEREARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDI 102
            +L RE  I   L+H NI+R+     ++   YL+ +    GEL++++
Sbjct: 3   HQLRREIEIQSHLRHDNILRMFGYFHDKTRVYLILEFAPKGELYKEL 143
>09007
          Length = 1440

 Score = 76.3 bits (186), Expect = 3e-14,   Method: Compositional matrix adjust.
 Identities = 60/230 (26%), Positives = 108/230 (46%), Gaps = 13/230 (5%)
 Frame = -1

Query: 12  DDYQLFEELGKGAFSVVRRCVKKTSTQE---YAAKIINTKKLSARDHQKLEREARICRLL 68
           D   L + LG+G F  VR+ +    + E    A K ++  K+  +D Q+  +E  I ++L
Sbjct: 879 DCVALSKSLGQGHFGTVRQAIWTAESGEKVQVAVKCLSKDKIH-KDGQEFLKETAIMQML 703

Query: 69  KHPNIVRLHDSISEEGFH-YLVFDLVTGGELFE---DIVAREYYSEADASHCIHQILESV 124
            H NIVR++  + + G    LV +L     L E   ++ AR  +S         Q+ + +
Sbjct: 702 DHENIVRVYGVVMDNGADIMLVTELAPMRSLLECVKEVSARVDFSVPRLCDFSQQVCDGM 523

Query: 125 NHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQG-----EQQAWFGFAGTPG 179
           +++    +VHRDL   N+LL SK K   VK++D G++  +       + Q          
Sbjct: 522 SYLESKRLVHRDLAARNILLFSKSK---VKISDVGVSGALGAGKEYYQSQQTIHLQNAVA 352

Query: 180 YLSPEVLRKDPYGKPVDIWACGVILYILLV-GYPPFWDEDQHKLYQQIKA 228
           + +PE  R   +    D+WA GV+L+     G+ P+   +  ++ + + A
Sbjct: 351 WCAPESFRNLCFSSASDVWAFGVLLWEFFTHGFQPWAGLNGQQIMEAVDA 202
>01966
          Length = 1735

 Score = 72.8 bits (177), Expect = 3e-13,   Method: Compositional matrix adjust.
 Identities = 58/190 (30%), Positives = 87/190 (45%), Gaps = 14/190 (7%)
 Frame = -1

Query: 28   VRR---CVKKTSTQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEG 84
            VRR   C  + + ++ A K I  +           RE  + R L+H NIV L D I E+ 
Sbjct: 1672 VRRGL*CRHRATGRKLAMKKIRLRGSEDGVPSSAIREIAMLRELRHTNIVCLEDVIMEDE 1493

Query: 85   FHYLVFDLVTG-----------GELFEDIVAREYYSEADASHCIHQILESVNHIHQHDIV 133
              +LVF+ ++            G + +  + + Y         + QI+  +N  HQ  IV
Sbjct: 1492 RLFLVFEFLSMDLKMYIDKFPEGVVLDRRLVKSY---------VFQIVTGINFCHQRRIV 1340

Query: 134  HRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKDPYGK 193
            HRDLKP+NLL+       A+K+ADFG+A       +A+     T  Y +PE+L   P   
Sbjct: 1339 HRDLKPQNLLINHT---GAIKIADFGMARTFALPVRAYTHEVVTLWYRAPEIL-MGPQST 1172

Query: 194  PVDIWACGVI 203
            P   W CG +
Sbjct: 1171 P-PXWTCGAL 1145

 Score = 32.0 bits (71), Expect = 0.60,   Method: Compositional matrix adjust.
 Identities = 28/112 (25%), Positives = 49/112 (43%), Gaps = 25/112 (22%)
 Frame = -3

Query: 191  YGKPVDIWACGVILYILLVGYPPFWDEDQ----HKLYQQI------------KAGAYDFP 234
            Y  PVD+W+ G I   +L+  P F  + +     K+++ I            K  A++  
Sbjct: 1175 YSTPVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIFRIIGTPTEQTWPEFHKLPAFNGM 996

Query: 235  SPEW------DTVT---PEAKNLINQMLTINPAKRITADQALKHPWVCQRST 277
             P W      +T+T       +LI + L  +PA+RI+  + L+H +     T
Sbjct: 995  FPLWKEGKLSETLTDLDSLGLDLIERTLKCDPAQRISCKKMLQHAYFLNVDT 840
>31885
          Length = 529

 Score = 71.2 bits (173), Expect = 8e-13,   Method: Compositional matrix adjust.
 Identities = 47/152 (30%), Positives = 78/152 (51%), Gaps = 5/152 (3%)
 Frame = -2

Query: 68  LKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESVNHI 127
           L HP +V L  +  +E   ++V DL  GG+L   +     + E      + Q+   ++++
Sbjct: 501 LDHPFLVNLWYAFQDEEDLFMVVDLFLGGDLRYHMQQEVSFREDCVKFYLCQLALVLDYL 322

Query: 128 HQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVL- 186
               IVHRD+KP+N+LL  +       + DF +A +++ ++ A    +GT  Y++PEV  
Sbjct: 321 RSQKIVHRDIKPDNILLDEQ---GHCHVTDFNIATQLEDDELA-TSTSGTRPYMAPEVYG 154

Query: 187 ----RKDPYGKPVDIWACGVILYILLVGYPPF 214
                +  YG PVD W+ GV L+ LL    PF
Sbjct: 153 VAINERRGYGFPVDWWSLGVSLFELLKKRRPF 58
>18921
          Length = 697

 Score = 70.5 bits (171), Expect = 1e-12,   Method: Compositional matrix adjust.
 Identities = 50/203 (24%), Positives = 99/203 (48%), Gaps = 1/203 (0%)
 Frame = +2

Query: 12  DDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREARICRLLKHP 71
           D + +  +LG+G++  V + + K + Q  A K +        D Q++ +E  I +     
Sbjct: 29  DVFDILGKLGEGSYGSVFKSLHKETGQVLAIKQVPVDT----DLQEIIKEISIMQQCDSK 196

Query: 72  NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAR-EYYSEADASHCIHQILESVNHIHQH 130
            IV+ + S  +    ++V +    G + + +  R +   E + +  ++  L+ + ++H  
Sbjct: 197 YIVKYYGSYFKNTDLWIVMEYCGAGSVSDIMRLRNKTLVEREIATILYYTLKGLXYLHSR 376

Query: 131 DIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKDP 190
             +HRD+K  N+LL ++      KLADFG+A ++           GTP +++PEV+++  
Sbjct: 377 RKIHRDIKAGNILLNNE---GHAKLADFGVAGQLTDTMAKRNTVIGTPYWMAPEVIQEIG 547

Query: 191 YGKPVDIWACGVILYILLVGYPP 213
           Y    DIW+ G+    +  G PP
Sbjct: 548 YDCVADIWSLGITALEMAEGKPP 616
>06405
          Length = 1965

 Score = 70.1 bits (170), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 60/214 (28%), Positives = 100/214 (46%), Gaps = 4/214 (1%)
 Frame = +1

Query: 20  LGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDS 79
           LG G +  V   + K   +  A K +    ++  D   LE EA I + +KHPN+V+L   
Sbjct: 283 LGGGQYGDVYEAMWKRYNKIVAVKTLKEDTMALNDF--LE-EAAIMKEMKHPNLVQLLGV 453

Query: 80  ISEEGFHYLVFDLVTGGELFEDIVA--REYYSEADASHCIHQILESVNHIHQHDIVHRDL 137
            + E   Y+V + +  G L + + +  RE        +   QI   + ++   + +HRDL
Sbjct: 454 CTREPPFYIVTEFMPHGNLLDYLRSSTREENGPTALMYMATQIASGMAYLETKNFIHRDL 633

Query: 138 KPENLLLASKCKGAAVKLADFGLAIEVQGEQ-QAWFGFAGTPGYLSPEVLRKDPYGKPVD 196
              N L+A       VK+ADFGLA  ++ +   A  G      + +PE L  + +    D
Sbjct: 634 AARNCLVAD---SNMVKVADFGLARLMKDDTYTAHIGAKFPIKWTAPEGLAFNRFSTRSD 804

Query: 197 IWACGVILYILLV-GYPPFWDEDQHKLYQQIKAG 229
           IWA GV+L+ L   G  P+   +  ++Y  ++ G
Sbjct: 805 IWAFGVLLWELATYGMSPYPGVELTEVYHLLERG 906
>28638
          Length = 1458

 Score = 61.2 bits (147), Expect(2) = 3e-12,   Method: Compositional matrix adjust.
 Identities = 33/86 (38%), Positives = 51/86 (59%)
 Frame = -1

Query: 129 QHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRK 188
           + +I+H DLKPEN+LL +  K +A+K+ DFG + ++    Q  + +  +  Y SPEVL  
Sbjct: 777 EMNIIHCDLKPENILLCNP-KRSAIKIVDFGSSCQLG---QRIYQYIQSRFYRSPEVLLG 610

Query: 189 DPYGKPVDIWACGVILYILLVGYPPF 214
            PY   +D+W+ G IL  +  G PP 
Sbjct: 609 VPYDLAIDMWSLGCILVEMHTGEPPL 532

 Score = 28.1 bits (61), Expect(2) = 3e-12,   Method: Compositional matrix adjust.
 Identities = 24/97 (24%), Positives = 41/97 (42%), Gaps = 12/97 (12%)
 Frame = -3

Query: 9    RFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKK------------LSARDHQ 56
            ++ D Y++   +GKG+F  V +       ++ A KII  KK            L   +  
Sbjct: 1156 KWLDRYEIDSLIGKGSFGQVVKAYDHGDQEQVAIKIIKNKKPFLNQAQIEVKLLELMNRH 977

Query: 57   KLEREARICRLLKHPNIVRLHDSISEEGFHYLVFDLV 93
              +    I RL +H  + R H  +  E   Y ++DL+
Sbjct: 976  DADNXYYIVRLKRH-FMFRNHLCLVFELLSYNLYDLL 869
>00486
          Length = 797

 Score = 69.3 bits (168), Expect = 4e-12,   Method: Compositional matrix adjust.
 Identities = 34/88 (38%), Positives = 53/88 (60%)
 Frame = -2

Query: 174 FAGTPGYLSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDF 233
           F GT  Y++PE+L +  +GK VD W+ G ++Y +L G PPF  E++ K   +I  G  + 
Sbjct: 778 FCGTIEYMAPEILTRTGHGKAVDWWSLGALMYDMLTGSPPFTAENRKKTIDKILKGKLNL 599

Query: 234 PSPEWDTVTPEAKNLINQMLTINPAKRI 261
           P      +T EA+ LI ++L  NPA+R+
Sbjct: 598 PP----YLTNEARGLIKKLLRKNPAERL 527
>19761
          Length = 473

 Score = 68.6 bits (166), Expect = 6e-12,   Method: Compositional matrix adjust.
 Identities = 47/140 (33%), Positives = 71/140 (50%), Gaps = 2/140 (1%)
 Frame = -3

Query: 117 IHQILESVNHIHQHD--IVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGF 174
           + Q   ++N++H H   I+HRDLKP+N+ +  K     V+L D GLA ++ G        
Sbjct: 405 LMQTASALNYMHTHTPVILHRDLKPQNIYVTEK---GDVRLGDLGLARKLTGPADFATSQ 235

Query: 175 AGTPGYLSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFP 234
            GT  YLSPE+L + PY    DIW+ G + Y  + G     +     L  Q+  G    P
Sbjct: 234 VGTIMYLSPEILSQQPYNSKSDIWSLGCVFYD-ITGKKGSDEMGVMFLLVQVMGGR-KLP 61

Query: 235 SPEWDTVTPEAKNLINQMLT 254
            P  D  + E ++ I++MLT
Sbjct: 60  LP--DHYSQEFRDTISRMLT 7
>29581
          Length = 1278

 Score = 67.8 bits (164), Expect = 9e-12,   Method: Compositional matrix adjust.
 Identities = 66/236 (27%), Positives = 107/236 (45%), Gaps = 32/236 (13%)
 Frame = -2

Query: 68   LKHPNIVRLHDSISEEGFH--YLVFDLVTG--GELFEDIVAREYYSEADASHCIHQILES 123
            L+H NIV+L + +  +     +LV +        L +++ A   +SE+     + Q+L+ 
Sbjct: 1184 LRHQNIVQLQEVVVGKSLDSLFLVMEYCEQDLASLLDNMPAP--FSESQVKCIVLQLLKG 1011

Query: 124  VNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSP 183
            + ++H+  I+HRDLK  NLL+  K     VK+ADFGLA      Q+       T  Y +P
Sbjct: 1010 LRYLHEAFIIHRDLKVSNLLMTDK---GCVKIADFGLARNYGKPQKPMTPKVVTLWYRAP 840

Query: 184  EVL-RKDPYGKPVDIWACGVILYILLVGYPPFW----DEDQHKLYQQ--------IKAGA 230
            E+L     +   +D+W+ G IL  LL G+ P      D  Q +L  +        I  G 
Sbjct: 839  ELLFGSKTHSTAIDMWSAGCILGELL-GHKPLMPGRSDLQQIELIMELLGTPNDTIWPGF 663

Query: 231  YDFPSPEWDTVTPEAKN---------------LINQMLTINPAKRITADQALKHPW 271
               P+ E  T+  +  N               L+N +   +P KR TA+  L+H +
Sbjct: 662  SQLPAFEQFTLKKQPYNNLRHTFPWLSESGIRLLNGLFMYHPQKRATAEDCLEHSY 495
>27405
          Length = 532

 Score = 66.6 bits (161), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 46/170 (27%), Positives = 80/170 (47%), Gaps = 5/170 (2%)
 Frame = -3

Query: 24  AFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREARICRLL-----KHPNIVRLHD 78
            F  V  C K  + + YA K ++ K++  +  + L    RI   L       P IV +  
Sbjct: 530 GFGEVYGCRKADTGKMYAMKCLDKKRIKMKGGETLALNERIMLSLVSTGEGSPFIVCMTY 351

Query: 79  SISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESVNHIHQHDIVHRDLK 138
           +         + DL+ GG+L   +     ++E +      +++  + H+H   +V+RDLK
Sbjct: 350 AFQTPEKLCFILDLMNGGDLHYHLSQHGVFTEKEVRFYAAEVMLGLEHMHSRFVVYRDLK 171

Query: 139 PENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRK 188
           P N+LL    +   V+++D GLA +    ++      GT GY++PEVL K
Sbjct: 170 PANILLD---ENGHVRISDLGLACDFS--KKKPHASVGTHGYMAPEVLMK 36
>01718
          Length = 959

 Score = 65.1 bits (157), Expect = 6e-11,   Method: Compositional matrix adjust.
 Identities = 53/198 (26%), Positives = 100/198 (50%), Gaps = 5/198 (2%)
 Frame = +3

Query: 12  DDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREARICRLLKHP 71
           DD+ + E++G G FS V +   + + Q  A K+ NT  +++  H  L RE ++   L+H 
Sbjct: 150 DDF-ICEKIGAGFFSEVFKVTHRITGQVMALKM-NT--MTSNRHNML-REVQLLNRLQHA 314

Query: 72  NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQIL---ESVNHIH 128
           NI+R       EG  + + + +  G L + +  ++   E   +  I   L     ++++H
Sbjct: 315 NILRFMGVCVHEGQLHALTEYIPSGNLEQLLEKKD--EELPWTQRIQLTLGLARGLDYLH 488

Query: 129 QHDIVHRDLKPENLLLASKCK-GAAVKLADFGLAIEVQGE-QQAWFGFAGTPGYLSPEVL 186
               +HRDL  +N+L+  +   G    +ADFGLA ++     +      G+P +++PEVL
Sbjct: 489 STRFIHRDLTSKNILIRREDNHGYHAVIADFGLATKIPDPLDKEKLPTVGSPYWMAPEVL 668

Query: 187 RKDPYGKPVDIWACGVIL 204
               Y +  D+++ G+I+
Sbjct: 669 NGHFYNERADLFSVGIIM 722
>38560
          Length = 479

 Score = 65.1 bits (157), Expect = 7e-11,   Method: Compositional matrix adjust.
 Identities = 44/121 (36%), Positives = 62/121 (51%), Gaps = 5/121 (4%)
 Frame = -3

Query: 176 GTPGYLSPEVLRKDPY-GKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFP 234
           G+P Y +PE++    Y G   DIW+ GV+LY LL GY PF DE    L Q+ +    +  
Sbjct: 399 GSPAYAAPELISGLEYLGSEADIWSMGVLLYALLCGYLPFDDEKXSHL*QKNQKRKDEV- 223

Query: 235 SPEWDTVTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTV----ASMMHRQETVEC 290
            PEW  ++ +   L+  ML  +P+ RIT  + L H W+ Q   V    AS   R    +C
Sbjct: 222 -PEW--LSEDTTKLLEGMLQTDPSHRITIRRLLDHHWLNQGFNVPVEWASKYKRTLDEDC 52

Query: 291 L 291
           L
Sbjct: 51  L 49
>00392
          Length = 668

 Score = 64.7 bits (156), Expect = 8e-11,   Method: Compositional matrix adjust.
 Identities = 49/194 (25%), Positives = 95/194 (48%), Gaps = 8/194 (4%)
 Frame = +3

Query: 45  INTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGFH-----YLVFDLVTGGELF 99
           +  KK +  + Q+ + EA + + L+HPNIVR  D   E          LV +L+T G L 
Sbjct: 33  LQDKKWNKAERQRFKEEAEMLKELQHPNIVRFFDYWEEHNHRNRKVIILVTELMTSGTLK 212

Query: 100 EDIVAREYYSEADASHCIHQILESVNHIHQHD--IVHRDLKPENLLLASKCKGAAVKLAD 157
             +   +  +     +   Q+L+ +  +H     ++HRDLK +N+ +       +VK+ D
Sbjct: 213 TYLKRFKKPNVKILKNWCRQVLKGLYFLHTRTPPVIHRDLKCDNIFITG--PTGSVKIGD 386

Query: 158 FGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWD- 216
            GLA      Q       GTP +++PE + ++ Y + VD++A G+ +  +     P+ + 
Sbjct: 387 LGLA--TLKNQSFAKSVIGTPEFMAPE-MYEEHYDEAVDVYAFGMCMLEMASSEYPYSEC 557

Query: 217 EDQHKLYQQIKAGA 230
            +  ++Y+++ +G 
Sbjct: 558 SNAAQIYKRVTSGV 599
>26560
          Length = 398

 Score = 64.7 bits (156), Expect = 8e-11,   Method: Composition-based stats.
 Identities = 37/113 (32%), Positives = 62/113 (54%), Gaps = 1/113 (0%)
 Frame = -1

Query: 108 YSEADASHCIHQILESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGE 167
           ++E +      +++  + H+H   +V+RDLKP N+LL    +   V+++D GLA +   +
Sbjct: 365 FTEKEVRFYAAEVMLGLEHMHSRFVVYRDLKPANILLD---ENGHVRISDLGLACDFSKK 195

Query: 168 QQAWFGFAGTPGYLSPEVLRK-DPYGKPVDIWACGVILYILLVGYPPFWDEDQ 219
           +       GT GY++PEVL K   Y    D ++ G +LY LL G+ PF   +Q
Sbjct: 194 RP--HASVGTHGYMAPEVLMKGQSYDSSADWFSFGCMLYKLLKGHSPFRQHNQ 42
>01756
          Length = 1858

 Score = 63.9 bits (154), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 58/206 (28%), Positives = 90/206 (43%), Gaps = 15/206 (7%)
 Frame = -3

Query: 14   YQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNI 73
            Y+   ++G+G F  V +   K + Q  A K +              RE +I +LL H N+
Sbjct: 1736 YEKLAKIGQGTFGEVFKARCKKTKQVVAMKKVLMDNEKEGFPITALREIKILQLLNHENV 1557

Query: 74   VRLHDSISEEG--------FHYLVFDLV---TGGELFEDIVAREYYSEADASHCIHQILE 122
            V L +  S +           YLVF+       G L    V    ++  +    + Q++ 
Sbjct: 1556 VDLIEICSTKATSANRYKSMFYLVFEFCEHDLAGLLSNMSVV---FNLPEIKEVMKQLMN 1386

Query: 123  SVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGL--AIEVQGEQ-QAWFGFAGTPG 179
             + +IH++ I+HRD+K  N+L+    K   +KLADFGL  A  V   Q   +     T  
Sbjct: 1385 GLYYIHRNKILHRDMKAANILIT---KQGVLKLADFGLARAFSVNLRQPNRYTNRVVTLW 1215

Query: 180  YLSPEVLRKD-PYGKPVDIWACGVIL 204
            Y  PE+L  D  Y   +D W  G I+
Sbjct: 1214 YRPPELLLGDRNYSTAIDQWGAGCIM 1137
>21808
          Length = 1011

 Score = 63.2 bits (152), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 49/195 (25%), Positives = 94/195 (48%), Gaps = 3/195 (1%)
 Frame = +1

Query: 45  INTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVA 104
           I T K    D +    EA+I + L+HP +++L+   +++   +++ +L+  G L E +  
Sbjct: 34  IKTLKSGTMDPKDFLAEAQIMKKLRHPKLIQLYAVCTQDDPIFIITELMKNGSLLEFLQG 213

Query: 105 REYYSEADASHCI-HQILESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIE 163
           +    +  A   I  QI   + ++   + +HRDL   N+L++       VK+ADFGLA  
Sbjct: 214 KGRVLKLPALIDIGAQIACGMAYLESQNYIHRDLAARNILVSDN---NTVKIADFGLARV 384

Query: 164 V-QGEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDIWACGVILY-ILLVGYPPFWDEDQHK 221
           + + E +A  G      + +PE    + +    D+W+ G++L   +  G  P+      +
Sbjct: 385 IKEDEYEARVGARFPIKWTAPEAANYNRFTIKSDVWSFGILLTETVTYGRVPYPGMTNAE 564

Query: 222 LYQQIKAGAYDFPSP 236
           +  Q++ G Y  P P
Sbjct: 565 VLHQVEHG-YRMPCP 606
>04591
          Length = 1117

 Score = 62.8 bits (151), Expect = 4e-10,   Method: Compositional matrix adjust.
 Identities = 66/252 (26%), Positives = 105/252 (41%), Gaps = 42/252 (16%)
 Frame = -2

Query: 60   REARICRLLKHPNIVRLHDSISEEG-------------FHYLVFDLVTGGELFEDIVARE 106
            RE +I + L+H N+V+L +    +              F Y  +DL     L  ++  R 
Sbjct: 1074 REIKILQQLEHENVVQLQEICHTQAGPYNRYKSTFYLIFEYCDYDLAG---LLNNL--RV 910

Query: 107  YYSEADASHCIHQILESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQG 166
             +S AD  + + Q+L  + +IH   I+HRD+K  N+LL    +   +KLADFGL+     
Sbjct: 909  KFSLADKKNLMSQLLNGLFYIHTKQILHRDIKAANILLT---RDGVLKLADFGLS-RPWV 742

Query: 167  EQQAWFGFAGTPGYLSPEVLRKD-PYGKPVDIWACGVILYILLVGYPPFWDE-DQHKLY- 223
            + +       T  Y  PE+L  +  YG  +D+W  G I+  +    P      +QH+L  
Sbjct: 741  KSKRLTNRVVTLWYRPPELLLGEREYGPEIDMWGVGCIMAEMWSRKPLMQGRSEQHQLSL 562

Query: 224  -----QQIKA------------GAYDFPSPEWDTV---------TPEAKNLINQMLTINP 257
                   + A            G  D P  +   V           E   LI+  L ++P
Sbjct: 561  ITDLCGSLNAEVWPGVTKLELYGKLDLPQGKPRKVKERMLDLLKNKEGAELIDIFLRLDP 382

Query: 258  AKRITADQALKH 269
             +R+  D AL H
Sbjct: 381  GQRMNCDNALSH 346
>27546
          Length = 426

 Score = 61.6 bits (148), Expect = 8e-10,   Method: Compositional matrix adjust.
 Identities = 38/103 (36%), Positives = 55/103 (53%), Gaps = 1/103 (0%)
 Frame = -1

Query: 60  REARICRLLKHPNIVRLHDSISEEGFHYLVF-DLVTGGELFEDIVAREYYSEADASHCIH 118
           RE  I   L HPNI+++H SI + G    +F      G++   I       EA       
Sbjct: 333 RELEILTRLDHPNIIQIH-SILQRGPKIFIFMRYAEKGDMLSHIKKTGPIDEAQTKVWFF 157

Query: 119 QILESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLA 161
           Q+ +++ ++H HDI HRDLK EN+LL+ +     VK+ADFG A
Sbjct: 156 QMAKALQYLHSHDIAHRDLKCENILLSKRLN---VKIADFGFA 37
>36002
          Length = 253

 Score = 60.5 bits (145), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 26/55 (47%), Positives = 34/55 (61%)
 Frame = +1

Query: 219 QHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITADQALKHPWVC 273
           Q  L+ +I+ G Y FPS EW  ++  AK+LI  +L   P KR +A   LKHPWVC
Sbjct: 49  QELLFNRIQDGNYFFPSMEWSAISSSAKDLIRHLLVREPRKRYSAADVLKHPWVC 213
>12786
          Length = 460

 Score = 60.5 bits (145), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 36/118 (30%), Positives = 56/118 (47%), Gaps = 22/118 (18%)
 Frame = -3

Query: 119 QILESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWF--GFAG 176
           ++L +V  +H   ++H DLKP N +L +      +KL DFG+A  +Q ++ +       G
Sbjct: 386 EMLRAVKALHNEGVIHSDLKPANFMLVA----GNLKLIDFGIANTLQQDKTSVLKDSRVG 219

Query: 177 TPGYLSPEVL-----------------RKDP---YGKPVDIWACGVILYILLVGYPPF 214
           TP Y+SPE +                 R  P    G   D+W+ G ILY ++ G  PF
Sbjct: 218 TPSYMSPEAIMAACDDSADDSMEEDGHRTKPKYKVGVRSDVWSLGCILYNMVYGRTPF 45
>19301
          Length = 712

 Score = 59.7 bits (143), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 45/155 (29%), Positives = 71/155 (45%), Gaps = 7/155 (4%)
 Frame = +2

Query: 12  DDYQL-------FEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREARI 64
           DD+++        E LG GA   V   + K   +E A K +   K         E + R 
Sbjct: 284 DDWEIPFESITDLEWLGSGAQGAV--FLGKLCAEEVAVKKVRDIK---------ETDIRN 430

Query: 65  CRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESV 124
            R L HPNI+      ++   + ++ +    G+L+E +   +    A       QI   +
Sbjct: 431 LRKLNHPNIISFKGVCTQAPCYCIIMEYCPYGQLYEVLRDGKEIPPALVLDWSKQIASGM 610

Query: 125 NHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFG 159
           N++H H I+HRDLK  N+L+A   K   VK++DFG
Sbjct: 611 NYLHSHKIIHRDLKSPNVLVA---KNDVVKISDFG 706
>21418
          Length = 831

 Score = 59.7 bits (143), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 23/57 (40%), Positives = 38/57 (66%)
 Frame = +2

Query: 222 LYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTV 278
           + ++I++G YDFP PEW  V+  AK+LI  ML ++P+KR+  +  L++ W+ Q   V
Sbjct: 2   MKKRIRSGQYDFPDPEWTNVSQAAKDLIKGMLNVDPSKRLCIEDVLRNKWIAQYDAV 172
>20152
          Length = 445

 Score = 58.9 bits (141), Expect = 4e-09,   Method: Compositional matrix adjust.
 Identities = 32/91 (35%), Positives = 48/91 (52%), Gaps = 1/91 (1%)
 Frame = +1

Query: 183 PEVLRKDPYGKP-VDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTV 241
           PE+L  D Y  P VD+W+ GVILY+L+VG  PF + +  +    I    Y  P      +
Sbjct: 1   PEILLGDSYDAPAVDVWSLGVILYMLVVGEAPFQEANDSETLTMIMDCRYQIPP----HI 168

Query: 242 TPEAKNLINQMLTINPAKRITADQALKHPWV 272
           + + ++LI +ML   P  R +    L HPW+
Sbjct: 169 SHKCQDLIEKMLQREPVDRASLPHILAHPWL 261
>04138
          Length = 800

 Score = 57.4 bits (137), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 57/187 (30%), Positives = 82/187 (43%), Gaps = 36/187 (19%)
 Frame = +1

Query: 122 ESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGL--AIEVQGEQ-QAWFGFAGTP 178
           E + +IH++ I+HRD+K  N+L+    K   +KLADFGL  A  V   Q   +     T 
Sbjct: 46  ERLYYIHRNKILHRDMKAANILI---TKQGVLKLADFGLARAFSVNLRQPNRYTNRVVTL 216

Query: 179 GYLSPEVLRKD-PYGKPVDIWACGVI---------------------LYILLVG--YPPF 214
            Y  PE+L  D  Y   +D W  G I                     L   L G   P  
Sbjct: 217 WYRPPELLLGDRNYSTAIDQWGAGCIMAEMWTRNPIMQGTTEQNQLTLITQLCGSITPEV 396

Query: 215 W-DEDQHKLYQQIK----AGAYDFPSPEWDTVT--PEAKNLINQMLTINPAKRITADQAL 267
           W    Q  +Y QIK    AG  +     +  +   P   +L  ++L ++P++RI+AD+AL
Sbjct: 397 WPGVTQLSMYHQIKGALAAGRKNIIRDRFARILKDPYGLDLFERLLKMDPSQRISADEAL 576

Query: 268 KHP--WV 272
            H   WV
Sbjct: 577 NHDFFWV 597
>18663
          Length = 600

 Score = 57.4 bits (137), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 35/97 (36%), Positives = 52/97 (53%), Gaps = 9/97 (9%)
 Frame = +2

Query: 174 FAGTPGYLSPEVLRKDPYGKPVDIWACGVILYILLVGYPPF------WDEDQHK---LYQ 224
           F GTP Y++PE+LR + YG  VD WA GV+LY +L G  PF       + DQ+    L+Q
Sbjct: 8   FCGTPNYIAPEILRGEDYGFSVDWWALGVLLYEMLAGRSPFDIAGASENPDQNTEDYLFQ 187

Query: 225 QIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRI 261
            I       P     +++ +A +++   L  NPA R+
Sbjct: 188 VILEKTIRIPR----SLSVKAASVLKGFLNKNPADRL 286
>31120
          Length = 439

 Score = 55.1 bits (131), Expect = 6e-08,   Method: Composition-based stats.
 Identities = 31/90 (34%), Positives = 49/90 (54%), Gaps = 1/90 (1%)
 Frame = +1

Query: 184 EVLRKDPYG-KPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVT 242
           EV+   PY  K  D W+ GVIL+I+L G  PF D + +KL +  ++  Y F     D V+
Sbjct: 1   EVVCGVPYDPKMADAWSLGVILFIMLNGKMPFDDSNLNKLLEDQRSKKYSFRRKLQDLVS 180

Query: 243 PEAKNLINQMLTINPAKRITADQALKHPWV 272
           P A++ ++ +L  N A R   ++ L   W+
Sbjct: 181 PNARSTVSVLLEPNSAMRWDLNEVLNCQWL 270
>19094
          Length = 898

 Score = 53.9 bits (128), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 28/93 (30%), Positives = 52/93 (55%)
 Frame = +1

Query: 110 EADASHCIHQILESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQ 169
           E + +  ++  L+ + ++H    +HRD+K  N+LL ++      KLADFG+A ++     
Sbjct: 55  EREIATILYYTLKGL*YLHSRRKIHRDIKAGNILLNNE---GHAKLADFGVAGQLTDTMA 225

Query: 170 AWFGFAGTPGYLSPEVLRKDPYGKPVDIWACGV 202
                 GTP +++PEV+++  Y    DIW+ G+
Sbjct: 226 KRNTVIGTPYWMAPEVIQEIGYDCVADIWSLGI 324
>20655
          Length = 1181

 Score = 53.5 bits (127), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 22/57 (38%), Positives = 34/57 (59%)
 Frame = +2

Query: 222 LYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTV 278
           + ++I+ G Y+FP PEW  V+ +AK+LI  ML  +P KR+   Q +   WV   + V
Sbjct: 2   MKKRIRNGQYEFPKPEWSRVSQDAKDLIRGMLCTDPDKRLNIKQVMASKWVADNTMV 172
>04852
          Length = 1462

 Score = 52.8 bits (125), Expect = 4e-07,   Method: Compositional matrix adjust.
 Identities = 49/218 (22%), Positives = 92/218 (42%), Gaps = 30/218 (13%)
 Frame = +1

Query: 50  LSARDHQKLEREARICRLLK----HPNIVRLHDSISEEGFHYLVFDLVTGGEL------- 98
           ++A + Q   +E ++ + +K    H NIV      ++ G  +++ +    G L       
Sbjct: 55  VTAVEEQDFVQELQVMKAVKKMGSHINIVNFLGCCTQGGPLWVIVEFAKNGNLRDFLESC 234

Query: 99  ------FEDIVARE---YYSEADASHCIH---------QILESVNHIHQHDIVHRDLKPE 140
                 +   V+ +   +Y++    H I          QI   +  +     +HRDL   
Sbjct: 235 RDGINGYGKFVSPQDPGWYTKTPGGHVIRRKNLLSYAFQIARGMEFLASRKCIHRDLAAR 414

Query: 141 NLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDIWAC 200
           N+L+  +     +K+ADFGL+      ++   G      +++PE L    Y    D+W+ 
Sbjct: 415 NVLVTEE---HVLKIADFGLSRTGDYYKKRSGGRLPVK-WMAPEALFDMRYTTKSDVWSF 582

Query: 201 GVILY-ILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPE 237
           GV+L+ I  +G  P+      +LY ++   AY  P PE
Sbjct: 583 GVVLWEIFSLGGMPYASIPNEELYSKLLDDAYRMPRPE 696
>11185
          Length = 473

 Score = 51.6 bits (122), Expect = 8e-07,   Method: Composition-based stats.
 Identities = 45/178 (25%), Positives = 79/178 (44%), Gaps = 23/178 (12%)
 Frame = +1

Query: 117 IHQILESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGE--QQAWFGF 174
           IH ++  +++IH   I+  DL+P  +LL +      +K ADFGL+ +V+GE  ++ +F F
Sbjct: 22  IH-LVTGLHYIHSLGILFHDLRPSKVLLDTS---GVLKFADFGLS-KVEGENLEELFFKF 186

Query: 175 A---------------------GTPGYLSPEVLRKDPYGKPVDIWACGVILYILLVGYPP 213
           A                     G+P Y++PEV +        D+WA G + Y +  G   
Sbjct: 187 AEAGDQWNIQSAEEMMKQVPTSGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFSG--- 357

Query: 214 FWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITADQALKHPW 271
                      ++ A     PSPE+        NL+  +L  +  +R++    +KH +
Sbjct: 358 ----------SRLSAK----PSPEF-------LNLLESLLQKDSTRRLSWASLVKHAF 468
>11780
          Length = 1713

 Score = 50.4 bits (119), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 42/153 (27%), Positives = 73/153 (47%), Gaps = 4/153 (2%)
 Frame = +3

Query: 13  DYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDH--QKLEREARICRLLKH 70
           D ++ E +GKG F  V + +       Y  + +  K+L  +D   Q   +EA +   L+H
Sbjct: 600 DLEIGEAIGKGDFGDVYKGM-------YRGQPVAIKQLKDKDRGEQSFLQEASVMTSLRH 758

Query: 71  PNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVA--REYYSEADASHCIHQILESVNHIH 128
            N+VRL   +  E   +LV + +  G L E + +  R   ++ D  +       ++ ++ 
Sbjct: 759 DNLVRLIGVVLGETI-FLVTEFMGKGNLVEYLRSRGRSVITKKDQINFATDTCAAMEYLE 935

Query: 129 QHDIVHRDLKPENLLLASKCKGAAVKLADFGLA 161
              +VHRDL   N+L+    K    K++DFGLA
Sbjct: 936 SKRLVHRDLAARNVLVHDDGK---AKVSDFGLA 1025
>28157
          Length = 400

 Score = 50.4 bits (119), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 39/134 (29%), Positives = 70/134 (52%), Gaps = 6/134 (4%)
 Frame = +3

Query: 38  QEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGE 97
           ++ A K I +++      Q+L++ +R+     HPNIV L+ +  +     LV +   GG 
Sbjct: 3   KDVAVKRIESEQEKKSFMQELKQLSRV----SHPNIVCLYGACRDHPV-CLVMEYAEGGS 167

Query: 98  LFEDIVAREYYSEADASHCIHQILE---SVNHIHQHD---IVHRDLKPENLLLASKCKGA 151
           L+  +       +  A+H ++ +L+    V ++H      ++HRDLKP NLLL  +C G 
Sbjct: 168 LYNVLHGSGPQPQYTAAHAMNWLLQCALGVEYLHGMKPKALIHRDLKPPNLLLI-QC-GT 341

Query: 152 AVKLADFGLAIEVQ 165
            +K+ DFG A ++ 
Sbjct: 342 KLKICDFGTACDIH 383
>00715
          Length = 1788

 Score = 50.4 bits (119), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 49/198 (24%), Positives = 84/198 (42%), Gaps = 29/198 (14%)
 Frame = +1

Query: 68  LKHPNIVRLHDSISEEGFH---YLVFDLVTGGELFEDIVAREYYSEADASHCIH---QIL 121
           L+H N+V +  + S   F    +L  + V  G L    +  ++  + D+S  +    Q+ 
Sbjct: 97  LRHVNVVSILGATSLHRFEDGAWLAMEYV--GPLNLQTILNDHQQDIDSSMRLSLALQMA 270

Query: 122 ESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLA-------------------- 161
             ++++H  +IVH DLKP N LL    K   +++ADFG                      
Sbjct: 271 RGLHYLHSINIVHLDLKPANCLLTRDLK---LRIADFGCCHQLTPTGLDMGEREGGMAGN 441

Query: 162 -IEVQGEQQAWFG-FAGTPGYLSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQ 219
            +E+   Q AW    AGT  Y +PE+L+        D+++ G+ L+ +     P+     
Sbjct: 442 ELELTPVQGAWKNELAGTLAYRAPELLKGLQPSVRSDVYSLGITLWQMCTRQGPYEGVPA 621

Query: 220 HK-LYQQIKAGAYDFPSP 236
           H  +YQ +       P P
Sbjct: 622 HAVVYQVVSKDLRPCPPP 675
>18481
          Length = 437

 Score = 50.1 bits (118), Expect = 2e-06,   Method: Composition-based stats.
 Identities = 36/125 (28%), Positives = 63/125 (50%), Gaps = 5/125 (4%)
 Frame = -1

Query: 49  KLSARD--HQKLEREARICRLL-KHPNIVRLHDSISEEGFHYLVFDLVTGG--ELFEDIV 103
           K+ A D  HQ L  EA++   + +HP +  ++   +E+ F+ LV +L+     ELF  ++
Sbjct: 392 KIEAIDVKHQLLHYEAKVYEQIGRHPGLPTMYHYGTEKHFNALVMELLGPSLEELF--VI 219

Query: 104 AREYYSEADASHCIHQILESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIE 163
            +  ++         Q+L  +  IHQ   +HRDLKP+N L+        + + DFGL+  
Sbjct: 218 CKRRFTLKTILMVSDQLLSRLEFIHQKCFIHRDLKPDNFLMGLGRHCHRLYIIDFGLSKR 39

Query: 164 VQGEQ 168
            +  Q
Sbjct: 38  YKDTQ 24
>27274
          Length = 396

 Score = 50.1 bits (118), Expect = 2e-06,   Method: Composition-based stats.
 Identities = 27/99 (27%), Positives = 51/99 (51%), Gaps = 8/99 (8%)
 Frame = -1

Query: 184 EVLRKDPYGKPVDIWACGVILYILLVGYPPFWDE--------DQHKLYQQIKAGAYDFPS 235
           E+LR   +G  VD+W+ G++L+ LL G+ PF  E        +   +Y QI  G+     
Sbjct: 375 ELLRGQQHGPTVDMWSLGILLHELLSGHVPFEPERGSRQMARNMMAVYAQIIRGS-SRDV 199

Query: 236 PEWDTVTPEAKNLINQMLTINPAKRITADQALKHPWVCQ 274
            +   ++    + + +++ +   KR+T+ QA  HPW+ +
Sbjct: 198 CDGLALSTHGADFLRRLVQLEDTKRLTSQQAFSHPWIAR 82
>31489
          Length = 329

 Score = 49.7 bits (117), Expect = 3e-06,   Method: Composition-based stats.
 Identities = 28/87 (32%), Positives = 51/87 (58%), Gaps = 6/87 (6%)
 Frame = +3

Query: 63  RICRLLKHPNIVRLHDSIS-EEGFH-----YLVFDLVTGGELFEDIVAREYYSEADASHC 116
           +I +  KH NI+ + + +  ++ +H     ++VFDL+   +L   I + +  +E    + 
Sbjct: 6   KILKHFKHDNIISIREILKPKDSYHDFKDIHVVFDLMES-DLHRIIYSDQPLTEEHIRYF 182

Query: 117 IHQILESVNHIHQHDIVHRDLKPENLL 143
           ++QIL  + +IH  ++VHRDLKP NLL
Sbjct: 183 LYQILRGLKYIHSANVVHRDLKPSNLL 263
>32000
          Length = 644

 Score = 49.7 bits (117), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 44/146 (30%), Positives = 69/146 (47%), Gaps = 25/146 (17%)
 Frame = -1

Query: 151 AAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRK-DPYGKPVDIWACGVILYILLV 209
           A +K+ADFGLA       + +     T  Y +PE+L     Y  PVDIW+ G I   ++ 
Sbjct: 578 AKMKIADFGLARVFGLPVRTYTHEVITLWYRAPEILLGCRFYSVPVDIWSLGCIFVEMMT 399

Query: 210 GYPPF-WDEDQHKLY----------QQIKAGAYDFPS-----PEW-----DTVTPEAK-- 246
               F  D +  +LY          +++  G    P      P+W     +TV   +K  
Sbjct: 398 RRALFPGDSEIDQLYRIFRTLGTPDEKVWPGVSKLPDYKPTFPKWPLKNLETVVSLSKVG 219

Query: 247 -NLINQMLTINPAKRITADQALKHPW 271
            +L+ +MLT NP +RI+A  A++HP+
Sbjct: 218 LDLLKRMLTYNPNRRISARSAMRHPY 141
>14116
          Length = 1017

 Score = 48.9 bits (115), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 50/202 (24%), Positives = 88/202 (43%), Gaps = 11/202 (5%)
 Frame = -1

Query: 18  EELGKGAFSVVRRCVKKTSTQE----YAAKIINTKKLSARDHQKLEREARICRLLKHPNI 73
           EE+GKG F  V+R       Q+     A K ++       + Q   +EA I +   H N+
Sbjct: 618 EEIGKGNFGCVKRGFLTLPEQKGDILVAVKTLHNNNPREIELQSFLQEALIMKDFHHSNV 439

Query: 74  VRLHD-SISEEGFHYLVFDLVTGGELFEDIVAREYY-SEADASHCIHQILESVNHIHQHD 131
           + L    ++ +    +V   +  G+L   I   ++  +  D       I   ++++    
Sbjct: 438 LTLIGICLNLDDMPLVVLPFMKHGDLLTYIRDDQHQPTIKDLIMYGVDIARGMDYLAGLK 259

Query: 132 IVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPG-----YLSPEVL 186
            VHRDL   N +L        VK+ADFGLA ++   ++ ++            +++ E L
Sbjct: 258 FVHRDLAARNCMLDEDFH---VKVADFGLARDIY--EKEYYSSENKKAKLPVKWMALESL 94

Query: 187 RKDPYGKPVDIWACGVILYILL 208
            K  Y    D+W+ GV+L+ LL
Sbjct: 93  EKGNYDSKTDVWSYGVVLWELL 28
>02638
          Length = 1490

 Score = 48.9 bits (115), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 30/109 (27%), Positives = 53/109 (48%), Gaps = 1/109 (0%)
 Frame = +1

Query: 163 EVQGEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDED-QHK 221
           E QG+        GT  +++PEVLR + YG+  D+W+ G ++  +    PP+   D  + 
Sbjct: 1   EFQGQ------LLGTIAFMAPEVLRGESYGRACDVWSVGCVMIEMCTCRPPWNSHDISNH 162

Query: 222 LYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITADQALKHP 270
           L    K  +   P P  + ++P  ++L+ + L  +   R +A   L HP
Sbjct: 163 LALIFKIASSVDPPPIPENMSPPVRDLMLRCLEQDSDFRPSAKDLLMHP 309
>17722
          Length = 680

 Score = 47.4 bits (111), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 23/72 (31%), Positives = 39/72 (54%)
 Frame = -3

Query: 195 VDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLT 254
           VD W  GV++Y ++ G  PF++ D   L++ I      FP      ++ EAK L++ +L 
Sbjct: 678 VDWWGTGVVMYEMMCGRLPFYNRDHDVLFELILLQNVKFPR----NLSEEAKTLLSGLLA 511

Query: 255 INPAKRITADQA 266
            NP +R+   +A
Sbjct: 510 KNPKRRLGGSEA 475
>03508
          Length = 1463

 Score = 46.2 bits (108), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 42/198 (21%), Positives = 90/198 (45%), Gaps = 5/198 (2%)
 Frame = +1

Query: 12  DDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREARICRLLKHP 71
           DDYQ+  +LG+G +S V   +  T+ +    K +       +  +       +  L    
Sbjct: 589 DDYQIVRKLGRGKYSEVFEAINVTNNE----KCVIKILKPVKKKKIKREIKILENLRGGT 756

Query: 72  NIVRL----HDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESVNHI 127
           N++ L     D +S      L+F+ V   +  +     + +++ D    +++++++++  
Sbjct: 757 NVITLLAIVKDPVSRTPA--LIFEHVNNTDFKQ---LYQTFTDYDIRFYLYELMKALDFC 921

Query: 128 HQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLR 187
           H   I+HRD+KP N+++  + K   ++L D+GLA E       +     +  +  PE+L 
Sbjct: 922 HSMGIMHRDVKPHNVMIDHENK--KLRLIDWGLA-EFYHPGMEYNVRVASRYFKGPELLL 1092

Query: 188 K-DPYGKPVDIWACGVIL 204
               Y   +D+W+ G + 
Sbjct: 1093DYQMYDYSLDMWSLGCMF 1146

 Score = 31.2 bits (69), Expect = 0.94,   Method: Compositional matrix adjust.
 Identities = 10/32 (31%), Positives = 23/32 (71%)
 Frame = +2

Query: 241  VTPEAKNLINQMLTINPAKRITADQALKHPWV 272
            ++PEA + ++++L  +  +R+TA +A+ HP+ 
Sbjct: 1358 ISPEALDFLDKLLRYDHNERLTAREAMDHPYF 1453
>07940
          Length = 1336

 Score = 45.8 bits (107), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 30/103 (29%), Positives = 52/103 (50%), Gaps = 6/103 (5%)
 Frame = -3

Query: 118 HQILESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGT 177
           +Q+   + ++     +HRDL   N+L+A +     +K+ADFGL    +  QQ  +    T
Sbjct: 326 YQVARGMEYLASKQCIHRDLAARNVLVAEEY---VLKIADFGLT---RNLQQFDYYRKTT 165

Query: 178 PG-----YLSPEVLRKDPYGKPVDIWACGVILY-ILLVGYPPF 214
            G     +++PE L    Y    D+W+ GV+L+ I  +G  P+
Sbjct: 164 DGRLPVKWMAPEALFDRKYTSKSDVWSYGVLLWEIFTLGGNPY 36
>17300
          Length = 480

 Score = 45.8 bits (107), Expect = 5e-05,   Method: Composition-based stats.
 Identities = 29/109 (26%), Positives = 53/109 (48%), Gaps = 7/109 (6%)
 Frame = +1

Query: 133 VHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPG------YLSPEVL 186
           VHRDL   N+L+         K+ADFGL+ E++ +     G   T G      + +PE +
Sbjct: 40  VHRDLAARNILVNEIL---VCKVADFGLSREIESDTTE--GAYTTKGGKIPVRWTAPEAI 204

Query: 187 RKDPYGKPVDIWACGVILY-ILLVGYPPFWDEDQHKLYQQIKAGAYDFP 234
               +    D+W+ GV+++ ++  G  P+W+     + + ++ G Y  P
Sbjct: 205 AYRKFTSASDVWSFGVVMWEVMSYGERPYWNWSNQDVIKAVEKG-YRLP 348
>29590
          Length = 320

 Score = 44.7 bits (104), Expect = 8e-05,   Method: Composition-based stats.
 Identities = 17/39 (43%), Positives = 25/39 (64%)
 Frame = +3

Query: 176 GTPGYLSPEVLRKDPYGKPVDIWACGVILYILLVGYPPF 214
           GTP Y++PEVL  +P     D+W+ GV+ Y++L    PF
Sbjct: 60  GTPDYVAPEVLDYEPLSIQTDMWSLGVLSYVMLTACSPF 176
>36481
          Length = 806

 Score = 44.7 bits (104), Expect = 9e-05,   Method: Compositional matrix adjust.
 Identities = 43/149 (28%), Positives = 66/149 (44%), Gaps = 7/149 (4%)
 Frame = +2

Query: 4   TATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKII-NTKKLSARDHQKLEREA 62
           T   T  T+D +L    G+G F  V +C       + A KII N  K   R+  KLE   
Sbjct: 338 TMRGTSSTNDMKLCPHWGEGTFGKVVQCKDLLKGDDIALKIIKNVDKY--REAAKLEINV 511

Query: 63  RICRLLKHPN----IVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREY--YSEADASHC 116
                 K P+     V++ D     G   + F ++ G  +F+ +    Y  Y      H 
Sbjct: 512 LEKLREKDPHAKHMCVQMLDWFDYHGHVCISFHML-GLSVFDFLKDNSYGAYPIEQVRHI 688

Query: 117 IHQILESVNHIHQHDIVHRDLKPENLLLA 145
            +Q+  +VN +H++ + H DLKPEN+L  
Sbjct: 689 SYQLCYAVNFLHENQLTHTDLKPENILFV 775
>25019
          Length = 730

 Score = 43.9 bits (102), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 26/62 (41%), Positives = 34/62 (54%)
 Frame = +3

Query: 140 ENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDIWA 199
           EN+LL    K   VKL DFGL  E     +    F GT  Y++PE+L +  +GK VD W+
Sbjct: 261 ENVLLD---KDGHVKLTDFGLCKEAITGTRVTHTFCGTIEYMAPEILTRTGHGKAVDWWS 431

Query: 200 CG 201
            G
Sbjct: 432 LG 437
>07291
          Length = 833

 Score = 43.9 bits (102), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 28/118 (23%), Positives = 59/118 (50%), Gaps = 6/118 (5%)
 Frame = +1

Query: 118 HQILESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGT 177
            QI + + ++ +  +VHR+L   N ++    +   ++L+D+G+   +    Q+++    +
Sbjct: 70  RQIADGMAYLQEVKVVHRNLAARNCIVTEDGR---LQLSDYGVTGSLF--PQSYYTADDS 234

Query: 178 PG-----YLSPEVLRKDPYGKPVDIWACGVILYILLV-GYPPFWDEDQHKLYQQIKAG 229
           P      +++PE +    +    D+WA GV+L+ LL  G  P+ D +   L   +K G
Sbjct: 235 PARDLVKWMAPETIDNFHFSSKSDVWAFGVVLWELLTRGITPYPDVENSSLLPYLKEG 408
>20773
          Length = 391

 Score = 43.1 bits (100), Expect = 2e-04,   Method: Composition-based stats.
 Identities = 18/39 (46%), Positives = 26/39 (66%)
 Frame = -1

Query: 236 PEWDTVTPEAKNLINQMLTINPAKRITADQALKHPWVCQ 274
           P    VT    NL+ ++LT +P++R+T D AL HP+VCQ
Sbjct: 337 PHTTVVTQHFYNLVQRLLTYDPSQRLTPDLALSHPFVCQ 221
>01106
          Length = 878

 Score = 42.4 bits (98), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 41/148 (27%), Positives = 68/148 (45%), Gaps = 12/148 (8%)
 Frame = +3

Query: 10  FTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKL---SARDHQKLEREARICR 66
           F   Y +  +LG G FS V  C   T  +  A K++ + +    +A D  KL +  R   
Sbjct: 312 FNGRYHVIRKLGWGHFSTVWLCWDLTCKRFVALKVVKSAQHYTETALDEVKLLKCVRESD 491

Query: 67  LLK--HPNIVRLHDSISEEGFH----YLVFDLVTGGELFEDIVAREYYSEA--DASHCIH 118
           +        V+L D     G +     +VF+ V G  L + I+   Y      +    I 
Sbjct: 492 VADPARAKCVQLLDDFKISGVNGTHVAMVFE-VLGYNLLKLIIRSNYQGIPIHNVKLIIR 668

Query: 119 QILESVNHIH-QHDIVHRDLKPENLLLA 145
           Q+LE ++++H +  I+H D+KPEN+L+ 
Sbjct: 669 QVLEGLSYMHAKCRIIHTDIKPENILIC 752
>32957
          Length = 645

 Score = 41.6 bits (96), Expect = 9e-04,   Method: Compositional matrix adjust.
 Identities = 21/51 (41%), Positives = 29/51 (56%)
 Frame = +3

Query: 158 FGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDIWACGVILYILL 208
           F L +E  G +     F GT  Y++PEV  +  YGK VD W  G++L+ LL
Sbjct: 3   FALCVEKSGGRTR--TFCGTREYMAPEVHERKEYGKEVDWWGLGILLHELL 149
>17644
          Length = 463

 Score = 41.2 bits (95), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 17/39 (43%), Positives = 25/39 (64%)
 Frame = +3

Query: 236 PEWDTVTPEAKNLINQMLTINPAKRITADQALKHPWVCQ 274
           P    VT    +L+ ++LT +P++R+T D AL HP+VCQ
Sbjct: 54  PHTTVVTQHFYBLVQRLLTYDPSQRLTPDLALSHPFVCQ 170
>18996
          Length = 491

 Score = 40.4 bits (93), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 30/113 (26%), Positives = 51/113 (45%), Gaps = 8/113 (7%)
 Frame = +2

Query: 133 VHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTP---GYLSPEVLRKD 189
           +HRDL   N+L+   C    VK++DFGLA +       ++G +       + SPE +   
Sbjct: 2   IHRDLAARNILVDRSC----VKISDFGLA-QFANADGYYYGISQRDIPIKWYSPEAIETC 166

Query: 190 PYGKPVDIWACGVILYIL-----LVGYPPFWDEDQHKLYQQIKAGAYDFPSPE 237
            +    D+W+ GV L+ +     +    P  D  Q +   +++ G    P PE
Sbjct: 167 KFSSYSDVWSYGVTLFEMFSRGEIPNLLPGHDLTQEEFLNRLRKGE-RLPKPE 322
>00394
          Length = 548

 Score = 40.0 bits (92), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 26/86 (30%), Positives = 42/86 (48%), Gaps = 5/86 (5%)
 Frame = -2

Query: 18  EELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLH 77
           +E+G+G+F  V + +        A   +  KK +  + Q+ + EA + + L+HPNIVR  
Sbjct: 280 KEIGRGSFKTVYKGLDTELGVAVAWCELQDKKWNKAERQRFKEEAEMLKELQHPNIVRFF 101

Query: 78  DSISEEGFH-----YLVFDLVTGGEL 98
           D   E          LV +L+T G L
Sbjct: 100 DYWEEHNHRNRKVIILVTELMTSGTL 23
>15549
          Length = 470

 Score = 40.0 bits (92), Expect = 0.002,   Method: Composition-based stats.
 Identities = 16/38 (42%), Positives = 24/38 (63%)
 Frame = -1

Query: 8   TRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKII 45
           +RF D+++  E++GKG + +V R   K   QEYA K I
Sbjct: 230 SRFADEFECIEQMGKGGYGIVFRAKNKVDEQEYAVKRI 117
>31789
          Length = 676

 Score = 39.7 bits (91), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 26/85 (30%), Positives = 41/85 (48%), Gaps = 5/85 (5%)
 Frame = +2

Query: 19  ELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHD 78
           E+G+G+F  V + +        A   +  KK +  + Q+ + EA + + L+HPNIVR  D
Sbjct: 341 EIGRGSFKTVYKGLDTELGVAVAWCELQDKKWNKTERQRFKEEAEMLKELQHPNIVRFFD 520

Query: 79  SISEEGFH-----YLVFDLVTGGEL 98
              E          LV +L+T G L
Sbjct: 521 YWEEHNHRNRKVIILVTELMTSGTL 595
>12672
          Length = 773

 Score = 38.5 bits (88), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 28/91 (30%), Positives = 46/91 (50%), Gaps = 4/91 (4%)
 Frame = +3

Query: 124 VNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEV-QGEQ---QAWFGFAGTPG 179
           + +++ +  VHRD+K  N+LL S+      K+ DF   +    GE    Q      GT  
Sbjct: 30  IQYLNDNGHVHRDIKTANILLDSEYTA---KVGDFATVVSAPSGEGKTVQNASVVIGTAA 200

Query: 180 YLSPEVLRKDPYGKPVDIWACGVILYILLVG 210
           YL+PE +  D   K +D ++ GV+L  ++ G
Sbjct: 201 YLAPEAIHFDVSTK-LDSYSFGVVLLEVITG 290
>11404
          Length = 563

 Score = 38.1 bits (87), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 38/153 (24%), Positives = 67/153 (43%), Gaps = 15/153 (9%)
 Frame = +1

Query: 9   RFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKK------------LSARDHQ 56
           ++ D Y++   +GKG+F  V +    T  ++ A KII  KK            L   +  
Sbjct: 130 KWADRYEIDSLIGKGSFGQVVKAYDHTDNEQVAIKIIKNKKPFLNQAQIEVKLLEMMNRH 309

Query: 57  KLEREARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDI---VAREYYSEADA 113
             + +  I RL +H  + R H  +  E   Y ++DL+     F  +   + R++  +   
Sbjct: 310 DTDNKYYIVRLKRHF-MFRSHLCLVFELLSYNLYDLLRNTN-FRGVSLNLTRKFAQQL-- 477

Query: 114 SHCIHQILESVNHIHQHDIVHRDLKPENLLLAS 146
             C   +  +   +    I+H DLKPEN+LL +
Sbjct: 478 --CTALLFLATPEM---SIIHCDLKPENILLCN 561
>18287
          Length = 678

 Score = 36.6 bits (83), Expect = 0.023,   Method: Compositional matrix adjust.
 Identities = 15/31 (48%), Positives = 23/31 (74%)
 Frame = -3

Query: 242 TPEAKNLINQMLTINPAKRITADQALKHPWV 272
           T EA  L+ +ML +NP  RI+A++AL HP++
Sbjct: 436 THEAVRLLTRMLILNPKNRISAEEALSHPYL 344
>18401
          Length = 463

 Score = 36.2 bits (82), Expect = 0.029,   Method: Compositional matrix adjust.
 Identities = 15/44 (34%), Positives = 23/44 (52%)
 Frame = -3

Query: 175 AGTPGYLSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDED 218
             T  Y +PEV+ +  +  P D+W+ G I++ L  GY  F   D
Sbjct: 449 VSTRHYRAPEVILELGWSHPCDVWSVGCIMFELYTGYTLFQTHD 318
>07836
          Length = 1478

 Score = 36.2 bits (82), Expect = 0.030,   Method: Compositional matrix adjust.
 Identities = 43/162 (26%), Positives = 73/162 (45%), Gaps = 23/162 (14%)
 Frame = -1

Query: 67   LLKHPNIVR-LHDSISEEGFH---YLVFDLVTGGELFEDIVAREYYSEADASHCIHQILE 122
            LL+H NI+  +   I   G     +L+ D    G L + +++R   S ++     H  + 
Sbjct: 1397 LLRHENILGFIAADIKGTGSWTQLFLITDYHENGSLHDYLLSRVLDS-SEMLALAHSAIC 1221

Query: 123  SVNHIH--------QHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQ----A 170
             + H+H        +  I HRD+K +N+L+    K     +AD GLA+    E      A
Sbjct: 1220 GLAHLHIEIFGTRGKPAIAHRDIKSKNILVK---KNGTCCIADLGLAVRYISESNEVDVA 1050

Query: 171  WFGFAGTPGYLSPEVLRK-------DPYGKPVDIWACGVILY 205
                 GT  Y++PEVL         D + K  D++A G++++
Sbjct: 1049 PNPRQGTKRYMAPEVLEMLLNVKNFDAF-KQADMYAFGLVMW 927
>37063
          Length = 455

 Score = 35.8 bits (81), Expect = 0.038,   Method: Composition-based stats.
 Identities = 26/83 (31%), Positives = 41/83 (49%), Gaps = 10/83 (12%)
 Frame = -2

Query: 137 LKPENLLLASKCKGAAVKLADFGLA--IEVQGE---QQAWFGFAGTPGYLSPEVL----- 186
           LKPEN+L     +   +K+ DF LA  I   G+           G+  Y++PEV+     
Sbjct: 454 LKPENILCEHLDEVVPLKICDFDLASGINCDGDGTKTPELLTPVGSAEYMAPEVVDAWVG 275

Query: 187 RKDPYGKPVDIWACGVILYILLV 209
               Y K  D+W+ G+IL +L++
Sbjct: 274 ESFSYDKRCDMWSLGIIL*VLVM 206
>21800
          Length = 855

 Score = 35.8 bits (81), Expect = 0.042,   Method: Compositional matrix adjust.
 Identities = 21/65 (32%), Positives = 35/65 (53%), Gaps = 3/65 (4%)
 Frame = +2

Query: 84  GFHYLVFDLVTGGELFEDIVAREYYSEA--DASHCIHQILESVNHIH-QHDIVHRDLKPE 140
           G H  +   V G  L + I+   Y      +    I Q+LE +N++H + +I+H D+KPE
Sbjct: 545 GTHVCMVFEVLGYNLLKLIIRSNYQGIPVHNVKLIIRQVLEGLNYLHAKCNIIHTDIKPE 724

Query: 141 NLLLA 145
           N+L+ 
Sbjct: 725 NILIC 739
>26009
          Length = 886

 Score = 35.8 bits (81), Expect = 0.044,   Method: Compositional matrix adjust.
 Identities = 12/33 (36%), Positives = 24/33 (72%)
 Frame = +3

Query: 112 DASHCIHQILESVNHIHQHDIVHRDLKPENLLL 144
           +A   + Q++ +++ +H   +VHRD+KPEN+L+
Sbjct: 714 EAKSVMKQLVSALDFMHSKQLVHRDIKPENVLI 812
>20559
          Length = 430

 Score = 35.4 bits (80), Expect = 0.049,   Method: Composition-based stats.
 Identities = 23/77 (29%), Positives = 36/77 (46%)
 Frame = -2

Query: 14  YQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNI 73
           Y+  E++G+G +  V +   + + +  A K +              RE  + + LKH NI
Sbjct: 369 YEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKHRNI 190

Query: 74  VRLHDSISEEGFHYLVF 90
           VRLHD +  E    LVF
Sbjct: 189 VRLHDVLHSERKLTLVF 139
>23319
          Length = 2235

 Score = 35.4 bits (80), Expect = 0.063,   Method: Compositional matrix adjust.
 Identities = 29/115 (25%), Positives = 51/115 (44%), Gaps = 26/115 (22%)
 Frame = +3

Query: 183 PEVLRKDPYGKPVDIWACGVILYILLVGYPPFW----DEDQHK-LYQQIKAGAYD----- 232
           P+V     Y   +D+W+ G I   L     P +    D+DQ K +++ +     D     
Sbjct: 3   PDVYXAKMYSTSIDMWSAGCIFAELANAGRPLFPGNDDDDQLKRIFKLLGTPTEDQWPGM 182

Query: 233 --------FP----SPEWDTVTP----EAKNLINQMLTINPAKRITADQALKHPW 271
                   FP    +  W  V P    + ++L+  +L   P+ R++AD+AL+HP+
Sbjct: 183 TQLPNYRMFPMYHVTTTWQQVVPKLNSKGRDLLQCLLVCCPSDRMSADEALQHPY 347
>20513
          Length = 405

 Score = 33.9 bits (76), Expect = 0.17,   Method: Compositional matrix adjust.
 Identities = 15/37 (40%), Positives = 23/37 (62%), Gaps = 1/37 (2%)
 Frame = -1

Query: 237 EWDTVTPEA-KNLINQMLTINPAKRITADQALKHPWV 272
           EWD    +A  + +  ML  +P +R TA Q+L+HPW+
Sbjct: 315 EWDPKDAKAFADFLAPMLEFDPEQRATAAQSLQHPWL 205
>37602
          Length = 804

 Score = 33.5 bits (75), Expect = 0.20,   Method: Compositional matrix adjust.
 Identities = 22/75 (29%), Positives = 37/75 (49%), Gaps = 5/75 (6%)
 Frame = -1

Query: 109 SEADASHCIHQILESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADF-----GLAIE 163
           +E   +    + L+ ++++H+   +HRD+K  N+LL  +     VKLADF       +  
Sbjct: 225 TEPQIAFVCRETLKGLHYLHRRGKMHRDIKGANILLTEE---GDVKLADFWRVSSNHSHN 55

Query: 164 VQGEQQAWFGFAGTP 178
           VQ +   W  F G P
Sbjct: 54  VQKKVFHWNAFIGWP 10
>29360
          Length = 363

 Score = 33.5 bits (75), Expect = 0.23,   Method: Compositional matrix adjust.
 Identities = 30/124 (24%), Positives = 53/124 (42%), Gaps = 8/124 (6%)
 Frame = +3

Query: 30  RCVKKTSTQEYAAKIINTKKLSARDHQKLEREARICRLLKHP-----NIVRLHDSISEEG 84
           +C KK +++  A KI+      AR  Q    E  I + L        N VR  +    + 
Sbjct: 6   KCWKKGTSEIVAIKILKNHPSYARQGQI---EVSILQRLSQESADDYNFVRAFECFQHKN 176

Query: 85  FHYLVFDLVTGGELFEDIVAREYYSEADASHC---IHQILESVNHIHQHDIVHRDLKPEN 141
              LVF+++       D + +  +      +      Q+L ++  + Q  ++H DLKPEN
Sbjct: 177 HTCLVFEMLEQN--LYDFLKQNKFQPLPLKYIRPITQQVLTALRKLKQLGLIHADLKPEN 350

Query: 142 LLLA 145
           ++L 
Sbjct: 351 IMLV 362
>32359
          Length = 928

 Score = 33.5 bits (75), Expect = 0.23,   Method: Compositional matrix adjust.
 Identities = 22/62 (35%), Positives = 33/62 (53%), Gaps = 5/62 (8%)
 Frame = -1

Query: 20  LGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSA-----RDHQKLEREARICRLLKHPNIV 74
           +G G+F VV           Y AK+++T +L A     +D +   RE +I R L+H NIV
Sbjct: 406 IGNGSFGVV-----------YQAKLVDTSELVAIKKVLQDKRFKNRELQIMRKLEHQNIV 260

Query: 75  RL 76
           +L
Sbjct: 259 KL 254
>22005
          Length = 873

 Score = 33.5 bits (75), Expect = 0.24,   Method: Compositional matrix adjust.
 Identities = 55/251 (21%), Positives = 92/251 (36%), Gaps = 61/251 (24%)
 Frame = +1

Query: 19  ELGKGAFSVVRRCVKKTSTQEYAAKIINTKKL----------SARDHQK-LEREARICRL 67
           ++G+GAF  V + +K         ++I  K+           ++ D Q   EREA +   
Sbjct: 4   DIGQGAFGRVSK-LKFLGLASLVGELIPEKRP*LL*KMLKEDASEDLQSDFEREASLMAD 180

Query: 68  LKHPNIVRLHDSISEEGFHYLVFDLVTGGEL--FEDIVAREYYS---------------- 109
             HPNIV+L    +      L+F+ ++ G+L  F  + + E Y+                
Sbjct: 181 FDHPNIVKLLGVCAIGKPMCLLFEFMSKGDLNDFLRLCSPENYNLPVSRSQNLVVDLEDG 360

Query: 110 ---EADASHC-----------------------IHQILESVNHIHQHDIVHRDLKPENLL 143
              E +A  C                         QI   + ++ Q D VHRDL      
Sbjct: 361 LRVEVEAEECEKDTQSEDRDCSGMLXTKDQLYISQQISAGMAYLAQKDYVHRDLATR--- 531

Query: 144 LASKCKGAAVKLADFGLAIEV------QGEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDI 197
                +     ++DFGLA  V      +G +Q        P     E +    +    D+
Sbjct: 532 -TVXSRTT*S*ISDFGLARSVHSVDYYRGSEQDAIPIRWMP----LEAILYSKFSTQSDV 696

Query: 198 WACGVILYILL 208
           W+ GV+L+ +L
Sbjct: 697 WSFGVVLWEIL 729
>17516
          Length = 453

 Score = 33.1 bits (74), Expect = 0.24,   Method: Composition-based stats.
 Identities = 16/38 (42%), Positives = 24/38 (63%), Gaps = 1/38 (2%)
 Frame = -3

Query: 174 FAGTPGYLSPEV-LRKDPYGKPVDIWACGVILYILLVG 210
            AGTP Y++PEV L+K  Y    D+++  +IL+ L  G
Sbjct: 439 LAGTPVYMAPEVLLQKGQYDMKADVYSLAIILWELWYG 326
>16350
          Length = 1108

 Score = 33.1 bits (74), Expect = 0.25,   Method: Compositional matrix adjust.
 Identities = 15/37 (40%), Positives = 23/37 (62%), Gaps = 1/37 (2%)
 Frame = +3

Query: 237 EWDTVTPEA-KNLINQMLTINPAKRITADQALKHPWV 272
           EWD    +A  + +  ML  +P +R TA Q+L+HPW+
Sbjct: 729 EWDPKDAKAFADFLAPMLEFDPEQRATAAQSLQHPWL 839

 Score = 31.2 bits (69), Expect = 1.0,   Method: Compositional matrix adjust.
 Identities = 25/83 (30%), Positives = 32/83 (38%), Gaps = 8/83 (9%)
 Frame = +2

Query: 136 DLKPENLLLASKCKGAAVKLADFGLAI--------EVQGEQQAWFGFAGTPGYLSPEVLR 187
           D KPE   +   C    VK+AD G A         ++Q  Q           Y   EVL 
Sbjct: 305 DNKPECDPVNEICTDFPVKIADLGNACWTYHHFTEDIQTRQ-----------YRCLEVLI 451

Query: 188 KDPYGKPVDIWACGVILYILLVG 210
              YG P DIW+   + + L  G
Sbjct: 452 GAGYGTPADIWSTACMAFELATG 520
>03106
          Length = 2384

 Score = 33.1 bits (74), Expect = 0.26,   Method: Compositional matrix adjust.
 Identities = 23/69 (33%), Positives = 32/69 (46%), Gaps = 1/69 (1%)
 Frame = +2

Query: 196 DIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEA-KNLINQMLT 254
           D+WA G + Y +     PF+       Y Q     +D PS   D  TPE    L+  ML 
Sbjct: 32  DVWAAGAVAYEIFGASNPFYSRLDSACYSQ-----HDLPSLPGD--TPEGVVRLVTSMLE 190

Query: 255 INPAKRITA 263
            +PA+R +A
Sbjct: 191 RDPAQRPSA 217
>16708
          Length = 1397

 Score = 32.7 bits (73), Expect = 0.37,   Method: Compositional matrix adjust.
 Identities = 15/43 (34%), Positives = 27/43 (62%)
 Frame = -1

Query: 119  QILESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLA 161
            Q + ++ HIH+  +VH D+K +N+L+ +       KL D+G+A
Sbjct: 1070 QXVCALEHIHELGVVHMDVKADNVLVDAH---GNCKLTDYGIA 951
>13305
          Length = 549

 Score = 32.0 bits (71), Expect = 0.65,   Method: Compositional matrix adjust.
 Identities = 15/51 (29%), Positives = 28/51 (54%), Gaps = 1/51 (1%)
 Frame = +2

Query: 180 YLSPEVLRKDPYGKPVDIWACGVILY-ILLVGYPPFWDEDQHKLYQQIKAG 229
           +++ E L  + Y    D+W+ GV+L+ I  +G  P+   D  +L+  +K G
Sbjct: 23  WMAVESLFNNTYTTQSDVWSFGVVLWEIFTLGGTPYSSTDTQQLFAFLKDG 175
>14104
          Length = 573

 Score = 31.6 bits (70), Expect = 0.74,   Method: Compositional matrix adjust.
 Identities = 11/36 (30%), Positives = 23/36 (63%)
 Frame = +1

Query: 237 EWDTVTPEAKNLINQMLTINPAKRITADQALKHPWV 272
           ++    P+A + +   L ++PA+R+T  Q L+HP++
Sbjct: 76  KFSNAAPQAMSFMQSCLKMDPAERLTCHQLLQHPYM 183
>03294
          Length = 1684

 Score = 30.4 bits (67), Expect = 1.9,   Method: Compositional matrix adjust.
 Identities = 27/109 (24%), Positives = 48/109 (44%), Gaps = 25/109 (22%)
 Frame = -1

Query: 194  PVDIWACGVILYILLVGYPPFWDEDQ----HKLYQQI------------KAGAYDFPSPE 237
            PVD+W+ G I   +L+  P F  + +     K+++ I            K  A++   P 
Sbjct: 1675 PVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIFRIIGTPTEQTWPEFHKLPAFNGMFPL 1496

Query: 238  W------DTVT---PEAKNLINQMLTINPAKRITADQALKHPWVCQRST 277
            W      +T+T       +LI + L  +PA+RI+  + L+H +     T
Sbjct: 1495 WKEGKLSETLTDLDSLGLDLIERTLKCDPAQRISCKKMLQHAYFLNVDT 1349
>17011
          Length = 1371

 Score = 30.0 bits (66), Expect = 2.1,   Method: Compositional matrix adjust.
 Identities = 12/26 (46%), Positives = 18/26 (69%)
 Frame = +1

Query: 247 NLINQMLTINPAKRITADQALKHPWV 272
           +LI  ++T NP  R+T D AL HP++
Sbjct: 1   DLILDVVTFNPDHRLTPDLALSHPFL 78
>33586
          Length = 551

 Score = 29.6 bits (65), Expect = 3.3,   Method: Compositional matrix adjust.
 Identities = 14/48 (29%), Positives = 25/48 (52%)
 Frame = +2

Query: 73  IVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQI 120
           IV LH +   EG  YL+ + + GG+LF  +     ++E D    + ++
Sbjct: 407 IVHLHYAFQTEGKLYLILEFLRGGDLFTRLSKEVMFTEEDVKFYLAEL 550
>12704
          Length = 641

 Score = 29.6 bits (65), Expect = 3.3,   Method: Compositional matrix adjust.
 Identities = 12/34 (35%), Positives = 21/34 (61%)
 Frame = +3

Query: 12  DDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKII 45
           DDYQ+  +LG+G +S V   +  T+ ++   KI+
Sbjct: 531 DDYQIVRKLGRGKYSEVFEAINITNNEKCVIKIL 632
>35032
          Length = 465

 Score = 28.9 bits (63), Expect = 5.2,   Method: Composition-based stats.
 Identities = 10/26 (38%), Positives = 19/26 (73%)
 Frame = +3

Query: 247 NLINQMLTINPAKRITADQALKHPWV 272
           +L+ ++L  +P+KR+T   AL HP++
Sbjct: 147 DLVKRLLNYDPSKRLTPXXALAHPFL 224
>31232
          Length = 993

 Score = 28.1 bits (61), Expect = 8.3,   Method: Compositional matrix adjust.
 Identities = 9/26 (34%), Positives = 20/26 (76%)
 Frame = +2

Query: 426 GNLVEGMDFHKFYFENLLSKNSKPIH 451
           G+++  +D ++FYF+N+L+K S  ++
Sbjct: 332 GDILNTLDMYRFYFKNILNKMSDKVN 409
>05487
          Length = 2308

 Score = 28.1 bits (61), Expect = 9.8,   Method: Compositional matrix adjust.
 Identities = 15/41 (36%), Positives = 19/41 (46%)
 Frame = +1

Query: 118  HQILESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADF 158
            H I  S  HIH  D+   +LK   LLL S+     +K   F
Sbjct: 1636 HXI*RSXLHIHYTDVSEFNLKTNLLLLGSRTSSVILKCGSF 1758
>00638
          Length = 1595

 Score = 28.1 bits (61), Expect = 10.0,   Method: Compositional matrix adjust.
 Identities = 8/32 (25%), Positives = 22/32 (68%)
 Frame = +2

Query: 108 YSEADASHCIHQILESVNHIHQHDIVHRDLKP 139
           +++ D    +++++++++  H   I+HRD+KP
Sbjct: 407 FTDYDIRFYLYELMKALDFCHSMGIMHRDVKP 502
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|113195686|ref|NP_034852.2| lamin B2 [Mus musculus]
         (596 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

02016                                                                 189   4e-48
19956                                                                 124   1e-28
26996                                                                 110   2e-24
10849                                                                  75   7e-14
11243                                                                  57   2e-08
17996                                                                  44   2e-04
25735                                                                  34   0.15 
19113                                                                  33   0.41 
02029                                                                  32   0.74 
>02016
          Length = 3061

 Score =  189 bits (479), Expect = 4e-48,   Method: Compositional matrix adjust.
 Identities = 138/435 (31%), Positives = 212/435 (48%), Gaps = 1/435 (0%)
 Frame = +3

Query: 126 RVKDLESLFHRSEAELATALSDKQGLETEVAELRAQLAKAEDGHAVAKKQLEKETLMRVD 185
           RV+ LE+      A+L  A    Q    E A LRA++A  E   A  KKQLE+ETL+RVD
Sbjct: 21  RVEGLEAQVADLTAKLNDAEVPSQETGKENAALRAEVAGLEKQLAKLKKQLEEETLLRVD 200

Query: 186 LENRCQSLQEELAFSKSXXXXXXXXXXXXXXXXXXXXDSSRQQEYDFKMAQALEDLRSQH 245
           LENR QSL+EE+ F                       D   + EY+ ++ +AL ++R+QH
Sbjct: 201 LENRLQSLKEEINFKSQVYEQELEESRVRTTVEIEQVDGRLEHEYEQRLLEALREIRAQH 380

Query: 246 DEQVRLYRVELEQTYQAKLDNAKLLSDQNDKAAHAAREELKEARMRVESLSYQLLGLQKQ 305
           +  ++  RVELE  Y+ K+ + K  +++++ A+ +A EEL+  R R + L  +L  L+ +
Sbjct: 381 ESDLQTVRVELETLYENKIADLKAQANRSNSASGSAWEELRITRKRADDLGAELAKLKAE 560

Query: 306 ASAAENHIHELEEALAGERDKFRKMLDAKEQEMTEVRDAMQQQLAEYQELLDIKLALDME 365
            +  E  I +LE  LA ER++FR  L  K+ E+ E+R  +++Q+ EY +LLDIK+ LD E
Sbjct: 561 TAGFELRISDLESQLAREREEFRLRLAQKDDELAELRLTLEEQMQEYSDLLDIKIRLDRE 740

Query: 366 ISAYXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGVGMSVGQGRG-KRRRLETEDT 424
           I AY                                      +   GRG KRRR+   D 
Sbjct: 741 IDAY---------RKLLESEESRLNISLDASQSSQTSRSPARATPSGRGTKRRRV---DI 884

Query: 425 XXXXXXXXXXXXXXXLAQQTVATGVVNIDEVDPEGRFVRLKNSSDKDQSLGNWRIKRQVL 484
                           A+   A G VNI EVD EG+F++L N   KD ++G+W+++    
Sbjct: 885 SEAVEEYSQKSSSSGFARAASAKGNVNIAEVDSEGKFIKLTNEGSKDVAIGSWQLQHTAG 1064

Query: 485 EGEDIAYKFTPKYVLRXXXXXXXXXXXXXXXHSPPSTLVWKSQTNWGPGESFRTALVSAD 544
           E +D  +KF    V++               H+PPS +V K +  W   +  +T L+  D
Sbjct: 1065E-QDTKFKFYRSLVVKAGKTVTIWSSDSDTTHNPPSDIVMKGK-RWFVADEMKTVLLDTD 1238

Query: 545 GEEVAVKAAKHSSVQ 559
            EE+A  +   SS++
Sbjct: 1239SEEMASCSMSKSSLR 1283
>19956
          Length = 536

 Score =  124 bits (310), Expect = 1e-28,   Method: Compositional matrix adjust.
 Identities = 74/157 (47%), Positives = 106/157 (67%)
 Frame = -3

Query: 43  RALELENDRLLLRISEKEEVTTREVSGIKTLYESELADARRVLDETARERARLQIEIGKV 102
           R LE EN+RL  +I   EE   REVS +K LYE+EL+DAR+VLDETA+E+AR+QIE    
Sbjct: 534 RYLEAENNRLSTQIQSTEETVKREVSSVKNLYENELSDARKVLDETAKEKARVQIEASTF 355

Query: 103 QAELEEARKSAKKREGELTVAQGRVKDLESLFHRSEAELATALSDKQGLETEVAELRAQL 162
           + + E+     K+R+ E + A+ RV++LE       A+L  A + +  L+ +++ LR+QL
Sbjct: 354 KTKYEDMLAKYKQRDREASGAEQRVENLEVQLADLSAKLNDADAARARLQKDMSGLRSQL 175

Query: 163 AKAEDGHAVAKKQLEKETLMRVDLENRCQSLQEELAF 199
           +  E     AK+Q+E+ETL+RVDLENR QSL+EEL F
Sbjct: 174 SSQEQQLGTAKQQIEEETLLRVDLENRVQSLKEELQF 64
>26996
          Length = 386

 Score =  110 bits (274), Expect = 2e-24,   Method: Compositional matrix adjust.
 Identities = 55/85 (64%), Positives = 68/85 (80%)
 Frame = -1

Query: 13  PLSPTRLSRLQEKEELRELNDRLAHYIDRVRALELENDRLLLRISEKEEVTTREVSGIKT 72
           P SPTR +R QE+E L+ LNDRLA+YIDRVR LE EN RL  ++   EE+  REVS +K 
Sbjct: 257 PPSPTRSTRQQEQESLQGLNDRLANYIDRVRFLEAENSRLSTQVQSTEEIVKREVSSVKN 78

Query: 73  LYESELADARRVLDETARERARLQI 97
           LYE+ELADARR+LD+TARE+AR+QI
Sbjct: 77  LYETELADARRLLDDTAREKARIQI 3
>10849
          Length = 1392

 Score = 75.1 bits (183), Expect = 7e-14,   Method: Compositional matrix adjust.
 Identities = 38/102 (37%), Positives = 58/102 (56%)
 Frame = +3

Query: 448 GVVNIDEVDPEGRFVRLKNSSDKDQSLGNWRIKRQVLEGEDIAYKFTPKYVLRXXXXXXX 507
           GV+ I EVDPEG+F++L N+  KD SLG+W++K  V   ++ A+KF    V++       
Sbjct: 81  GVMQISEVDPEGKFIKLTNTGSKDSSLGSWQVK-HVAGDQETAFKFHRSLVVKADSCVTV 257

Query: 508 XXXXXXXXHSPPSTLVWKSQTNWGPGESFRTALVSADGEEVA 549
                   HSPP+ +V K +  W   +  +T L ++D EEVA
Sbjct: 258 WSADTEATHSPPTDVVMKGK-RWFVNDEMKTTLFNSDEEEVA 380
>11243
          Length = 828

 Score = 57.4 bits (137), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 52/198 (26%), Positives = 89/198 (44%), Gaps = 1/198 (0%)
 Frame = -2

Query: 173 KKQLEKETLMRVDLENRCQSLQEELAF-SKSXXXXXXXXXXXXXXXXXXXXDSSRQQEYD 231
           ++ L++ TL + DLE   +SL+EEL +  K+                    DS+      
Sbjct: 803 RRVLDELTLNKTDLELEIESLKEELIYLKKNHEEELAVVRSSARGNVDVQVDSAP----P 636

Query: 232 FKMAQALEDLRSQHDEQVRLYRVELEQTYQAKLDNAKLLSDQNDKAAHAAREELKEARMR 291
             +AQ + D+RSQ++  +   R ELE  Y+ + +N       N  A   ++  + + +  
Sbjct: 635 VDLAQIMXDVRSQYESMMEKNRQELEACYKGQSENLNHEVATNTAALQTSKTAITDLKRT 456

Query: 292 VESLSYQLLGLQKQASAAENHIHELEEALAGERDKFRKMLDAKEQEMTEVRDAMQQQLAE 351
           ++SL  +L  L     A E  + E E     + +  + M+   E E+  +R     Q  E
Sbjct: 455 IQSLEIELQSLLSMKGALEGTLAETEAQYGAQLNHLQAMITQVEMELQNLRSDADHQSLE 276

Query: 352 YQELLDIKLALDMEISAY 369
           Y+ LLD K  L+MEI+ Y
Sbjct: 275 YKRLLDAKTRLEMEIATY 222
>17996
          Length = 475

 Score = 44.3 bits (103), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 18/40 (45%), Positives = 23/40 (57%)
 Frame = +2

Query: 516 HSPPSTLVWKSQTNWGPGESFRTALVSADGEEVAVKAAKH 555
           H+PP+ +VWK Q  WG G    T L  A+G+ VA   A H
Sbjct: 83  HNPPTDIVWKEQQKWGSGPECTTILCRANGQAVAWTTAAH 202
>25735
          Length = 442

 Score = 34.3 bits (77), Expect = 0.15,   Method: Compositional matrix adjust.
 Identities = 34/100 (34%), Positives = 50/100 (50%)
 Frame = +1

Query: 67  VSGIKTLYESELADARRVLDETARERARLQIEIGKVQAELEEARKSAKKREGELTVAQGR 126
           V G++T  +S     RR ++E  RE+  LQ ++  +  ELE AR+   +R G       R
Sbjct: 28  VRGMETKEQSMDGTFRRTVEENQREKYELQRKVTSLTTELEVARE---ERAG----VTAR 186

Query: 127 VKDLESLFHRSEAELATALSDKQGLETEVAELRAQLAKAE 166
             DLE+     E ++A  +S   GL  EV E R +  KAE
Sbjct: 187 RLDLENTVRNLERDVAEKVSKFDGLIREVEETRKRTDKAE 306
>19113
          Length = 1042

 Score = 32.7 bits (73), Expect = 0.41,   Method: Compositional matrix adjust.
 Identities = 34/107 (31%), Positives = 52/107 (48%), Gaps = 4/107 (3%)
 Frame = -3

Query: 98  EIGKVQAELEEARKSAKKREGELTVAQGRVKDLESLFHRSEAELA----TALSDKQGLET 153
           E+  +Q   E   KS  + E EL   Q   KDL+     ++ EL     ++ SDK   + 
Sbjct: 977 ELNDMQGMYE---KSMNELEDELQSTQAENKDLKDELQDTKIELDRNVRSSTSDKMFTDL 807

Query: 154 EVAELRAQLAKAEDGHAVAKKQLEKETLMRVDLENRCQSLQEELAFS 200
           EV ELR +LA A+D  +    +L     +  D E + Q+L++EL  S
Sbjct: 806 EVKELRRKLADAQDEVS----RLRIRCGLVDDYERKIQNLKDELYLS 678
>02029
          Length = 1497

 Score = 32.0 bits (71), Expect = 0.74,   Method: Compositional matrix adjust.
 Identities = 18/63 (28%), Positives = 30/63 (47%)
 Frame = +1

Query: 487 EDIAYKFTPKYVLRXXXXXXXXXXXXXXXHSPPSTLVWKSQTNWGPGESFRTALVSADGE 546
           ++ A+KF    V++               HSPP+ +V K +  W   +  +T L ++D E
Sbjct: 4   QETAFKFHRSLVVKADSCVTVWSADTEATHSPPTDVVMKGK-RWFVNDEMKTTLFNSDEE 180

Query: 547 EVA 549
           EVA
Sbjct: 181 EVA 189
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|46559745|ref|NP_997542.1| hook homolog 3 [Mus
musculus]
         (718 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

33298                                                                 189   4e-48
28040                                                                  30   2.5  
01964                                                                  30   3.7  
24037                                                                  29   6.1  
>33298
          Length = 1182

 Score =  189 bits (479), Expect = 4e-48,   Method: Compositional matrix adjust.
 Identities = 113/266 (42%), Positives = 165/266 (62%), Gaps = 3/266 (1%)
 Frame = -2

Query: 445  LGSQESSDSLAAEI--VTPEIREKLIRLQHENKMLKLNQEDSDNEKIALLQSLLDDANLR 502
            +G    S S  AE+  V PEI+E+L+RL+HENKMLK+    + NE+  +LQS LDD+N R
Sbjct: 1169 MGDVGPSSSQRAEMLSVPPEIKEQLLRLEHENKMLKMGTSGTQNEESQILQSQLDDSNAR 990

Query: 503  KNELETENRLVNQRLLEVQSQVEELQKSLQDQGSKAEDSVXXXXXXXXXXXXXXXANN-E 561
             +EL+TE RL+NQR+LE Q+QVE+LQ+      S +   V                   +
Sbjct: 989  NHELQTEVRLLNQRVLETQAQVEDLQEKQSSTESASSTEVLEMKKRVTEQTQKMEEKELQ 810

Query: 562  LQKKRAIIEDLEPRFNNSSLRIEELQEALXXXXXXXXXXXXXXXXXLEKAKSVIRTLDPK 621
            L ++ A ++ ++   + S+ ++  LQ+ L                 LEKAK+VI++LD  
Sbjct: 809  LAQRXAQLDQVKTELSTSTEKMAALQDTLARKDEEMRAMEERYKRYLEKAKTVIKSLDMN 630

Query: 622  QNQGAAPEIQALKNQLQERDRLFHSLEKEYEKTKSQRDMEEKYIVSAWYNMGMTLHKKAA 681
            Q+   +PE+ +LK+QL E+D+  + +EKE+EK +S  D EE+ IV+AWYN+GM LH++AA
Sbjct: 629  QSLDTSPELVSLKHQLLEKDQYINLVEKEHEKMRSVHDEEERLIVTAWYNLGMQLHRQAA 450

Query: 682  EDRLASTGSGQSFLARQRQATSTRRS 707
            E+RLA+   GQSFLARQRQ  STRRS
Sbjct: 449  EERLANNNMGQSFLARQRQVHSTRRS 372
>28040
          Length = 433

 Score = 30.4 bits (67), Expect = 2.5,   Method: Compositional matrix adjust.
 Identities = 15/31 (48%), Positives = 22/31 (70%)
 Frame = +3

Query: 261 LEAAKDDYRIRCEELEKEISELRQQNDELTT 291
           LEA  +DY  R ++LE +ISEL ++ D+L T
Sbjct: 219 LEAVTEDYNDRAQDLEAQISELEKRRDQLET 311
>01964
          Length = 2512

 Score = 30.0 bits (66), Expect = 3.7,   Method: Compositional matrix adjust.
 Identities = 39/145 (26%), Positives = 62/145 (42%), Gaps = 14/145 (9%)
 Frame = -3

Query: 369  ETYKRQVVELQNRLSDESKKADKLDFEYKRLKE--------------KVDGLQKEKDRLR 414
            E+Y++++  LQ++    S    K +    +LKE              KVD L+ + D LR
Sbjct: 2078 ESYRKEIAALQDKCQKYSTSVAKHELTITKLKEDVFEKQQQASTWEAKVDQLRAQYDTLR 1899

Query: 415  TERDSLKETIEELRCVQAQEGQLTTQGLMPLGSQESSDSLAAEIVTPEIREKLIRLQHEN 474
            T    L   +E LR  +  +  LT              +L A      I+  L R + E+
Sbjct: 1898 THEQRLVAELESLRRERQSQAMLTA-------------NLQA------IQNNLERAEFES 1776

Query: 475  KMLKLNQEDSDNEKIALLQSLLDDA 499
            K    NQ DS  +++ALL+  L +A
Sbjct: 1775 KTRYTNQIDSMEKEVALLRRRLQNA 1701
>24037
          Length = 2006

 Score = 29.3 bits (64), Expect = 6.1,   Method: Compositional matrix adjust.
 Identities = 37/95 (38%), Positives = 48/95 (50%), Gaps = 7/95 (7%)
 Frame = +2

Query: 271 RCEELEKEISELRQQNDELTTLADEAQ-------SLKDEIDVLRHSSDKVSKLEGQVESY 323
           RCE   K  +EL QQ      LA E Q        L+DE+ VLR  S K+SK   Q E+ 
Sbjct: 128 RCE---KARAELDQQITITDALASENQIRAAQLKHLEDEVHVLRTESQKLSK---QNEAI 289

Query: 324 KKKLEDLGDLRRQVKLLEEKNTMYMQNTVSLEEEL 358
            +KL    D R +V  + E++T+  Q T  LE EL
Sbjct: 290 HRKLRQADDHRAEV--IAERDTLRNQLT-GLEREL 385
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31982664|ref|NP_080198.2| inosine triphosphatase [Mus
musculus]
         (198 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

17412                                                                 186   6e-48
38549                                                                  27   5.3  
>17412
          Length = 540

 Score =  186 bits (472), Expect = 6e-48,   Method: Compositional matrix adjust.
 Identities = 85/128 (66%), Positives = 103/128 (80%), Gaps = 2/128 (1%)
 Frame = -1

Query: 63  QVQGPVLVEDTCLCFNALGGLPGPYIKWFLQKLKPEGLHQLLAGFEDKSAYALCTFALST 122
           Q++GPV+VEDT LCFNALGG+PGPYIKWFL+++KPEGLH+LLAGF+DKSAYALC F  S+
Sbjct: 540 QIKGPVIVEDTSLCFNALGGMPGPYIKWFLKEIKPEGLHKLLAGFDDKSAYALCIFGYSS 361

Query: 123 GDPSQ--PVLLFRGQTSGQIVMPRGSRDFGWDPCFQPDGYEQTYAEMPKSEKNTISHRFR 180
           G P     V +F G+  G IV PRG  DFGWDPCFQP+G+ QTYAEMPK  KN ISHR +
Sbjct: 360 GQPGAVPEVKIFPGRCDGTIVSPRGPPDFGWDPCFQPNGFTQTYAEMPKETKNGISHRGK 181

Query: 181 ALHKLQEY 188
           A+  L+E+
Sbjct: 180 AMASLKEF 157
>38549
          Length = 797

 Score = 26.9 bits (58), Expect = 5.3,   Method: Compositional matrix adjust.
 Identities = 14/45 (31%), Positives = 20/45 (44%)
 Frame = -3

Query: 82  GLPGPYIKWFLQKLKPEGLHQLLAGFEDKSAYALCTFALSTGDPS 126
           G+PG  +K+  + L       L   F D   Y LC   +  G+PS
Sbjct: 762 GVPGLMLKYLFKTLDNRTYFSL---FNDSQTYTLCYVTI*WGEPS 637
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|45597447|ref|NP_035564.1| superoxide dismutase 1,
soluble [Mus musculus]
         (154 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

05159                                                                 185   6e-48
17261                                                                  26   5.6  
>05159
          Length = 1454

 Score =  185 bits (470), Expect = 6e-48,   Method: Compositional matrix adjust.
 Identities = 91/152 (59%), Positives = 117/152 (76%)
 Frame = -1

Query: 3    MKAVCVLKGDGPVQGTIHFEQKASGEPVVLSGQITGLTEGQHGFHVHQYGDNTQGCTSAG 62
            +  VCVL  +  V+GT+HF ++       + G+++GL EG+HGFH+HQ+GD T GC SAG
Sbjct: 1247 VTGVCVLISE-KVKGTLHFTEQDG--MTTVKGEVSGLDEGKHGFHIHQFGDTTNGCVSAG 1077

Query: 63   PHFNPHSKKHGGPADEERHVGDLGNVTAGKDGVANVSIEDRVISLSGEHSIIGRTMVVHE 122
            PHFNP  K+HGGP  E RH GDLGN+TA  +GVA V+I+D+ I L+G +SIIGRT+VVH 
Sbjct: 1076 PHFNPAGKQHGGPTVENRHAGDLGNITASAEGVAAVNIQDKQIPLTGPNSIIGRTLVVHA 897

Query: 123  KQDDLGKGGNEESTKTGNAGSRLACGVIGIAQ 154
            K+DDLGKGG++ES KTGNAG R+ACGVIGI Q
Sbjct: 896  KEDDLGKGGDDESLKTGNAGGRIACGVIGICQ 801
>17261
          Length = 512

 Score = 26.2 bits (56), Expect = 5.6,   Method: Compositional matrix adjust.
 Identities = 10/23 (43%), Positives = 15/23 (65%)
 Frame = -3

Query: 19  IHFEQKASGEPVVLSGQITGLTE 41
           IHF  K+S  P+  S ++ G+TE
Sbjct: 159 IHFNMKSSRSPITESRRLLGITE 91
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|18087731|ref|NP_080832.1| dynein light chain LC8-type
2 [Mus musculus]
         (89 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

01814                                                                 184   1e-47
23693                                                                 183   1e-47
01266                                                                 182   2e-47
07799                                                                  62   4e-11
00691                                                                  60   2e-10
31148                                                                  51   1e-07
12798                                                                  45   8e-06
01422                                                                  28   1.1  
00539                                                                  26   4.4  
10347                                                                  25   6.0  
>01814
          Length = 605

 Score =  184 bits (466), Expect = 1e-47,   Method: Compositional matrix adjust.
 Identities = 84/89 (94%), Positives = 89/89 (100%)
 Frame = +3

Query: 1   MSDRKAVIKNADMSEDMQQDAVDCATQAMEKYNIEKDIAAYIKKEFDKKYNPTWHCIVGR 60
           MS+RKAVIKNADM+EDMQQDAVDCATQA+EKYNIEKDIAAY+KKEFDKKYNPTWHCIVGR
Sbjct: 96  MSERKAVIKNADMAEDMQQDAVDCATQALEKYNIEKDIAAYVKKEFDKKYNPTWHCIVGR 275

Query: 61  NFGSYVTHETKHFIYFYLGQVAILLFKSG 89
           NFGSYVTHETKHFIYFYLGQVA+LLFKSG
Sbjct: 276 NFGSYVTHETKHFIYFYLGQVAMLLFKSG 362
>23693
          Length = 1305

 Score =  183 bits (465), Expect = 1e-47,   Method: Compositional matrix adjust.
 Identities = 85/89 (95%), Positives = 89/89 (100%)
 Frame = -3

Query: 1    MSDRKAVIKNADMSEDMQQDAVDCATQAMEKYNIEKDIAAYIKKEFDKKYNPTWHCIVGR 60
            MS+RKAVIKNADM+EDMQQDAVDCATQA+EKYNIEKDIAA+IKKEFDKKYNPTWHCIVGR
Sbjct: 1099 MSERKAVIKNADMAEDMQQDAVDCATQALEKYNIEKDIAAFIKKEFDKKYNPTWHCIVGR 920

Query: 61   NFGSYVTHETKHFIYFYLGQVAILLFKSG 89
            NFGSYVTHETKHFIYFYLGQVAILLFKSG
Sbjct: 919  NFGSYVTHETKHFIYFYLGQVAILLFKSG 833
>01266
          Length = 1690

 Score =  182 bits (463), Expect = 2e-47,   Method: Compositional matrix adjust.
 Identities = 83/89 (93%), Positives = 89/89 (100%)
 Frame = -1

Query: 1    MSDRKAVIKNADMSEDMQQDAVDCATQAMEKYNIEKDIAAYIKKEFDKKYNPTWHCIVGR 60
            MS+RKAVIKNADM+EDMQQDAVDCATQA+EKYNIEKDIAA+IKKEFDKKYNPTWHCIVGR
Sbjct: 1594 MSERKAVIKNADMAEDMQQDAVDCATQALEKYNIEKDIAAFIKKEFDKKYNPTWHCIVGR 1415

Query: 61   NFGSYVTHETKHFIYFYLGQVAILLFKSG 89
            NFGSYVTHETKHF+YFYLGQVA+LLFKSG
Sbjct: 1414 NFGSYVTHETKHFVYFYLGQVAVLLFKSG 1328
>07799
          Length = 1797

 Score = 62.4 bits (150), Expect = 4e-11,   Method: Compositional matrix adjust.
 Identities = 30/83 (36%), Positives = 54/83 (65%), Gaps = 2/83 (2%)
 Frame = +1

Query: 7   VIKNADMSEDMQQDAVDCATQAMEKYNIEKDIAA-YIKKEFDKKYNPTWHCIVGRNFGSY 65
           +I+++DM+++M+ +A++    A EK+    + AA  IK   DKK+  +WH +VG  +G  
Sbjct: 802 LIRHSDMNDEMKTEAMELCVTACEKFASNNENAAKMIKDTMDKKFGASWHAVVGEGYGFE 981

Query: 66  VTHETKHFIY-FYLGQVAILLFK 87
           +THE K+ +Y F+ G +AI ++K
Sbjct: 982 ITHEVKNLLYMFFGGNMAICVWK 1050
>00691
          Length = 933

 Score = 60.1 bits (144), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 27/29 (93%), Positives = 29/29 (100%)
 Frame = +3

Query: 61  NFGSYVTHETKHFIYFYLGQVAILLFKSG 89
           +FGSYVTHETKHFIYFYLGQVA+LLFKSG
Sbjct: 114 HFGSYVTHETKHFIYFYLGQVAMLLFKSG 200
>31148
          Length = 442

 Score = 50.8 bits (120), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 25/84 (29%), Positives = 52/84 (61%), Gaps = 2/84 (2%)
 Frame = -1

Query: 6   AVIKNADMSEDMQQDAVDCATQAMEKYNIEK-DIAAYIKKEFDKKYNPTWHCIVGRNFGS 64
            +I+++DM+++M+ +A++    A EK   +  + +   ++   +K+  +WH +VG  FG 
Sbjct: 334 PLIRHSDMNDEMKTEAMELCVTACEKICKQ**ECSQDDQRHNGQKFGASWHAVVGEGFGF 155

Query: 65  YVTHETKHFIY-FYLGQVAILLFK 87
            +THE K+ +Y F+ G +AI ++K
Sbjct: 154 EITHEVKNLLYMFFGGNLAICIWK 83
>12798
          Length = 358

 Score = 44.7 bits (104), Expect = 8e-06,   Method: Compositional matrix adjust.
 Identities = 20/58 (34%), Positives = 37/58 (63%), Gaps = 1/58 (1%)
 Frame = +3

Query: 7   VIKNADMSEDMQQDAVDCATQAMEKYNIEKDIAA-YIKKEFDKKYNPTWHCIVGRNFG 63
           +I+++DM+++M+ +A++    A EK+    + AA  IK   DKK+  +WH +VG  +G
Sbjct: 168 LIRHSDMNDEMKTEAMELCVTACEKFASNNENAAKMIKDTMDKKFGASWHAVVGEGYG 341
>01422
          Length = 1823

 Score = 27.7 bits (60), Expect = 1.1,   Method: Composition-based stats.
 Identities = 12/17 (70%), Positives = 14/17 (82%)
 Frame = -3

Query: 72   HFIYFYLGQVAILLFKS 88
            +FIY YLGQVA+ L KS
Sbjct: 1434 NFIYIYLGQVAVKLLKS 1384
>00539
          Length = 1372

 Score = 25.8 bits (55), Expect = 4.4,   Method: Composition-based stats.
 Identities = 11/17 (64%), Positives = 13/17 (76%)
 Frame = +1

Query: 72  HFIYFYLGQVAILLFKS 88
           +FIY  LGQVA+ L KS
Sbjct: 457 NFIYIXLGQVAVKLLKS 507
>10347
          Length = 1123

 Score = 25.4 bits (54), Expect = 6.0,   Method: Composition-based stats.
 Identities = 13/38 (34%), Positives = 17/38 (44%), Gaps = 5/38 (13%)
 Frame = +3

Query: 54  WHCIVGRNFGSYVTHETKHFIYFY-----LGQVAILLF 86
           W C+ G  F  +V H     +Y Y     LG V  LL+
Sbjct: 282 WGCLFGLGFCLFVPHGIFFILYLYSNRINLGHVDCLLY 395
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|157951664|ref|NP_031629.3| calpain 6 [Mus musculus]
         (641 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

28393                                                                 186   2e-47
16109                                                                  80   9e-22
12911                                                                  66   5e-11
22144                                                                  63   3e-10
23206                                                                  43   4e-04
32442                                                                  41   0.002
30646                                                                  34   0.20 
18677                                                                  32   1.1  
12807                                                                  29   5.7  
>28393
          Length = 726

 Score =  186 bits (472), Expect = 2e-47,   Method: Compositional matrix adjust.
 Identities = 102/246 (41%), Positives = 149/246 (60%), Gaps = 4/246 (1%)
 Frame = -3

Query: 319 DDGEFWMSLEDFCHNFHKLNVCRNVNNPVFGRKEL--ESVV-GCWTVDDDPLMNRSGGCY 375
           +DGEFWM+ EDFC +FH+  +CR VN   F   ++  E +  G W   D     R+GGC 
Sbjct: 715 EDGEFWMTFEDFCKHFHQTAICRVVNTSFFSLSKMWHEGLSHGAWKGPD-----RAGGCP 551

Query: 376 NNRDTFLQNPQYIFTVPEDGHKVIMSLQQKDLRTYRRMGRPDNYIIGFELFKVEMNRRFR 435
           NN+++FL+NPQ +F V +D  + +  L QK  R         N  IGF + KVE+NRR+R
Sbjct: 550 NNKESFLKNPQXVFDVGDD-EEFMAQLMQKSTRDKDGSA---NKTIGFTVLKVELNRRYR 383

Query: 436 LHHLYIQERAGTSTYIDTRTVFLSKY-LKKGSYVLVPTMFQHGRTSEFLLRIFSEVPVQL 494
           +H L +QERA ++ Y D+R++FL    +KKG YV+VP+ F+  + +EFLLR+++      
Sbjct: 382 IHDLSLQERATSTVYRDSRSIFLRHGPMKKGRYVIVPSTFEPNQEAEFLLRVYTTDSNNF 203

Query: 495 RELTLDMPKMSCWNLARGYPKVVTQITVHSAEGLEKKYANETVNPYLIIKCGKEEVRSPV 554
            ELT D+P  S WN     P +VTQ+ V  A GLEK+   +  +PY +I C  E+V + V
Sbjct: 202 MELTQDVPTKSWWNCCGKAPVMVTQVKVVKAVGLEKQDV-QGADPYCVISCEGEKVSTRV 26

Query: 555 QKNTVH 560
           + NTV+
Sbjct: 25  ESNTVN 8
>16109
          Length = 1490

 Score = 79.7 bits (195), Expect(2) = 9e-22,   Method: Compositional matrix adjust.
 Identities = 35/85 (41%), Positives = 54/85 (63%)
 Frame = +1

Query: 271 VFSTEKLYMVRLRNPLGRQEWSGPWSEISEEWQQLTVTDRKNLGLVMSDDGEFWMSLEDF 330
            +  +K  ++ LRNP GR EW+G WS+ S+EW +L V++R    L+  D+GEFWMS+EDF
Sbjct: 49  TYRGKKTLLLLLRNPFGRGEWNGAWSDKSKEWSELRVSERSTEALLRRDNGEFWMSVEDF 228

Query: 331 CHNFHKLNVCRNVNNPVFGRKELES 355
             NF ++ +C    + +   +EL S
Sbjct: 229 KANFDEVELCHLSVDALTAERELAS 303

 Score = 42.4 bits (98), Expect(2) = 9e-22,   Method: Compositional matrix adjust.
 Identities = 36/121 (29%), Positives = 57/121 (47%), Gaps = 10/121 (8%)
 Frame = +3

Query: 380 TFLQNPQYIFTVPEDGHKVIMSLQQKDLRTYRRMGRP-DNYIIGFELFKVEMNRR----- 433
           +F  NPQY   + ED  K  +S+    L    +  R  ++  IGF +FK++  +      
Sbjct: 396 SFWTNPQYRIKL-EDKDKDKLSVVISLLEVTDKFERATEDVSIGFVIFKLKPGKEPIGKL 572

Query: 434 ----FRLHHLYIQERAGTSTYIDTRTVFLSKYLKKGSYVLVPTMFQHGRTSEFLLRIFSE 489
               F  H   + + +G       R++  S  L+ GSYV++P  F+    +EF LRIFSE
Sbjct: 573 DSENFYEHSPQLVDTSGVFWPYRERSIHFS--LETGSYVIIPCTFKANMEAEFHLRIFSE 746

Query: 490 V 490
            
Sbjct: 747 T 749
>12911
          Length = 469

 Score = 65.9 bits (159), Expect = 5e-11,   Method: Composition-based stats.
 Identities = 33/93 (35%), Positives = 57/93 (61%), Gaps = 2/93 (2%)
 Frame = +1

Query: 441 IQERAGTSTYIDTRTVFLSKY--LKKGSYVLVPTMFQHGRTSEFLLRIFSEVPVQLRELT 498
           +QE+  ++ Y D+R++FL +Y  + +G YV+VP+ F+ G+ +++LLRI++       EL 
Sbjct: 4   VQEKTTSTVYRDSRSIFL-RYGPVSRGRYVVVPSTFEAGQEAQYLLRIYTSASNNFVELK 180

Query: 499 LDMPKMSCWNLARGYPKVVTQITVHSAEGLEKK 531
            + P    WN     P +VTQ+ V  A GL+K+
Sbjct: 181 EEGPIKPWWNCLGKAPAMVTQVKVIKAIGLQKQ 279
>22144
          Length = 634

 Score = 63.2 bits (152), Expect = 3e-10,   Method: Composition-based stats.
 Identities = 46/165 (27%), Positives = 74/165 (44%), Gaps = 16/165 (9%)
 Frame = -1

Query: 441 IQERAGTSTYIDTRTVFL-----SKYLKKGSYVLVPTMFQHGRTSEFLLRIFSEVPVQLR 495
           +QE+  ++ Y D     L     S+   +G  V    + + G+ +++LLRI++       
Sbjct: 631 VQEKTTSTVYRDQSLHLLRYGPVSRGRLRGRAV---NLLKRGQEAQYLLRIYTSASNNFV 461

Query: 496 ELTLDMPKMSCWNLARGYPKVVTQITVHSAEGLEKKYANETVNPYLIIKCGKEEVRSPVQ 555
           EL  + P    WN     P +VTQ+ V  A GL+K+ A +  +PY +I C  E V + V+
Sbjct: 460 ELKEEGPIKPWWNCLGKAPAMVTQVKVIKAIGLQKQDA-QGADPYCVISCEGERVTTKVE 284

Query: 556 KNTVHAIFDTQAIF-----------YRRTTDIPIIIQVWNSRKFC 589
            N V   +   A+F           YR  T I  +I  W +   C
Sbjct: 283 XNXVDPEWGEAAVFIVNIPSNPPSKYRYGTTIXXVINTWENTCSC 149

 Score = 28.9 bits (63), Expect = 6.0,   Method: Compositional matrix adjust.
 Identities = 25/76 (32%), Positives = 37/76 (48%), Gaps = 3/76 (3%)
 Frame = -3

Query: 569 FYRR-TTDIPIIIQVWNSRKFCDQFLGQ-VTLDADPSDCRDLK-SLYLRKKGGPTAKVKQ 625
           FYR+     P+ IQ+WN     DQ+LG+ V +  D      L+ +L+ RK  G  +  K 
Sbjct: 245 FYRKHPLKSPLKIQIWNDNXLRDQYLGKHVFMSTDDFYNSPLEVNLFGRK--GERSTQKP 72

Query: 626 GHISFKVISSDDLTEL 641
           G +   V  S  LT +
Sbjct: 71  GKLQLLVTQSRRLTAV 24
>23206
          Length = 1611

 Score = 42.7 bits (99), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 31/94 (32%), Positives = 46/94 (48%), Gaps = 5/94 (5%)
 Frame = -3

Query: 119 GIFHFRFWHFGEWTEVVIDDLLP-TINGDLVFSFSTSMNEFWNALLEKAYAKL--LGCYE 175
           G +  R +  G W ++++DDLLP   N  L+   +T  +E W  LL KA  K+  L    
Sbjct: 859 GKYIVRLFWMGCWRKILVDDLLPFDENDQLLLPATTLSHELWPMLLAKAIIKVASLDYSG 680

Query: 176 ALDGLTITDI--IMDFTGTLAEIIDMQKGRYTDL 207
              G    DI  I   +G L E I +Q+G  T++
Sbjct: 679 GNPGAEFGDITVIHCLSGWLPEAIPIQQGHLTEV 578
>32442
          Length = 221

 Score = 40.8 bits (94), Expect = 0.002,   Method: Composition-based stats.
 Identities = 20/54 (37%), Positives = 30/54 (55%)
 Frame = +2

Query: 188 DFTGTLAEIIDMQKGRYTDLVEEKYKLFGELYKTFTKGGLICCSIESPSQEEQE 241
           DFTG +A+ +D+ K    + VEE+  LF  + K   +  L+  SI + S EE E
Sbjct: 8   DFTGGVADTLDLLKMEVANKVEERIALFSRMQKEVDRRSLMAASIPAASSEEME 169
>30646
          Length = 476

 Score = 33.9 bits (76), Expect = 0.20,   Method: Compositional matrix adjust.
 Identities = 38/156 (24%), Positives = 68/156 (43%), Gaps = 6/156 (3%)
 Frame = +3

Query: 323 FWMSLEDFCHNFHKLNVCR-----NVNNPVFGRKELESVVGCWTVDDDPLMNRSGGCYNN 377
           FW+ LEDF   F +  +C      +++        + +V G W          +   +  
Sbjct: 3   FWICLEDFMTYFDQTTICSLTPDFDMDGSSDFLNYVTNVYGEW-------RGETAAGFRQ 161

Query: 378 RDTFLQNPQYIFTVPED-GHKVIMSLQQKDLRTYRRMGRPDNYIIGFELFKVEMNRRFRL 436
           +   LQNP+ +FTVPE  G +V + +Q   L  +R     +N+ +  +L+KV +     +
Sbjct: 162 K---LQNPRILFTVPESAGAEVPVVVQ---LIQWRDSRSAENFQVRCDLYKV-LGDDGEV 320

Query: 437 HHLYIQERAGTSTYIDTRTVFLSKYLKKGSYVLVPT 472
             L        S   +T+  F  K +  G+Y +VP+
Sbjct: 321 AVLASMGENTNSYCPETQCSFRHK-VTPGTYAVVPS 425
>18677
          Length = 754

 Score = 31.6 bits (70), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 16/51 (31%), Positives = 28/51 (54%)
 Frame = +2

Query: 439 LYIQERAGTSTYIDTRTVFLSKYLKKGSYVLVPTMFQHGRTSEFLLRIFSE 489
           L +  R+GT  Y+  R       +  G YV+VP+ F     ++F++R+F+E
Sbjct: 65  LLLARRSGT--YVFYRECTKRFEMPPGDYVIVPSTFHPHEEAKFMMRLFTE 211
>12807
          Length = 1754

 Score = 29.3 bits (64), Expect = 5.7,   Method: Compositional matrix adjust.
 Identities = 13/26 (50%), Positives = 18/26 (69%), Gaps = 1/26 (3%)
 Frame = +3

Query: 323 FWMSLEDF-CHNFHKLNVCRNVNNPV 347
           FW+SLEDF C  F K++  R+ N P+
Sbjct: 135 FWVSLEDFVCRRFKKVSYSRSSNVPL 212
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|162139827|ref|NP_032641.2| malic enzyme 1,
NADP(+)-dependent, cytosolic [Mus musculus]
         (572 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

35371                                                                 186   2e-47
25767                                                                 148   6e-36
15625                                                                  30   2.6  
20428                                                                  30   3.5  
29818                                                                  28   6.8  
>35371
          Length = 631

 Score =  186 bits (473), Expect = 2e-47,   Method: Compositional matrix adjust.
 Identities = 100/208 (48%), Positives = 119/208 (57%), Gaps = 2/208 (0%)
 Frame = -3

Query: 176 LYTACGGVNPQQCLPITLDVGTENEELLKDPLYIGLRHRRVRGPEYDAFLDEFMEAASSK 235
           LYTA    +     P+            +DPLY+GLR +RV G EYD F+DEFMEA   +
Sbjct: 629 LYTALAASSRINVCPLWWMWAPITLICWEDPLYVGLRQKRVVGREYDDFIDEFMEAVVKR 450

Query: 236 YGMNCLIQFEDFANRNAFRLLNKYRNKYCTFNDDIQGTXXXXXXXXXXXXRITKNKLSDQ 295
           YG N LIQFEDF N NAFR L+KYR+ YCTFNDDIQGT            RIT   L D 
Sbjct: 449 YGQNTLIQFEDFGNHNAFRFLDKYRDTYCTFNDDIQGTAAVAVAGLYASKRITGKSLKDY 270

Query: 296 TVLFQGAGEAALGIAHLVVMAMEKEGLSKENARKKIWLVDSKGLIVKGR--ASLTXXXXX 353
           T LF GAGEAA+GIA LVV  M  EG+  + A  KI++VD  GL+ K R   SL      
Sbjct: 269 TFLFAGAGEAAIGIADLVVKGMVAEGVPIDEAYSKIFMVDIDGLLTKSRKVGSLEGHKVN 90

Query: 354 XXXXXXXMKNLEAIVQKIKPTALIGVAA 381
                  M NL+ IV  +KP+ LIG +A
Sbjct: 89  YAKDIEPMSNLDEIVTTVKPSVLIGASA 6
>25767
          Length = 426

 Score =  148 bits (374), Expect = 6e-36,   Method: Compositional matrix adjust.
 Identities = 67/115 (58%), Positives = 88/115 (76%)
 Frame = -2

Query: 10  HTHQRGYLLTRDPHLNKDLAFTLEERQQLNIHGLLPPCIISQELQVLRIIKNFERLNSDF 69
           H+  RG  + R P LNK  AF+L+ERQ + IHGLLPP + + + Q++R++ NF++  +D 
Sbjct: 347 HSRIRGIDILRSPKLNKGTAFSLKERQLMGIHGLLPPVVRTLDEQMVRVMTNFQKRQTDL 168

Query: 70  DRYLLLMDLQDRNEKLFYSVLMSDVEKFMPIVYTPTVGLACQQYSLAFRKPRGLF 124
           DRY+ LM LQDRNE+LFY VL   VE+ +PIVYTPTVGLACQQY +AFR+PRGLF
Sbjct: 167 DRYIYLMSLQDRNERLFYHVLTKYVEEMLPIVYTPTVGLACQQYGVAFRRPRGLF 3
>15625
          Length = 360

 Score = 30.0 bits (66), Expect = 2.6,   Method: Composition-based stats.
 Identities = 17/42 (40%), Positives = 27/42 (64%), Gaps = 1/42 (2%)
 Frame = +3

Query: 101 VYTPTVGLACQQYSLAFRKPRGLF-ISIHDKGHIASVLNAWP 141
           +Y     L C+Q SL FRK RG F ++ ++K ++ ++L AWP
Sbjct: 69  LY*MNASLGCRQ*SLCFRK-RGKFKMAGNNKHNLITLLYAWP 191
>20428
          Length = 1014

 Score = 29.6 bits (65), Expect = 3.5,   Method: Compositional matrix adjust.
 Identities = 17/43 (39%), Positives = 27/43 (62%), Gaps = 1/43 (2%)
 Frame = -2

Query: 101 VYTPTVGLACQQYSLAFRKPRGLF-ISIHDKGHIASVLNAWPE 142
           +Y     L C+Q SL FRK RG F ++ ++K ++  +L AWP+
Sbjct: 536 LY*MNASLGCRQ*SLCFRK-RGKFKMAGNNKHNLIMLLYAWPK 411
>29818
          Length = 887

 Score = 28.5 bits (62), Expect = 6.8,   Method: Compositional matrix adjust.
 Identities = 14/40 (35%), Positives = 22/40 (55%)
 Frame = +3

Query: 119 KPRGLFISIHDKGHIASVLNAWPEDVVKAIVVTDGERILG 158
           K RGLF+ +H   H+A+ + + P     + VV   ER+ G
Sbjct: 624 KQRGLFVVLHLAWHVAAAMLSSPRQKGLSAVVRVRERLFG 743
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|19527194|ref|NP_598734.1| component of oligomeric
golgi complex 4 [Mus musculus]
         (785 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

17755                                                                 187   2e-47
13811                                                                  35   0.11 
12155                                                                  29   8.0  
>17755
          Length = 769

 Score =  187 bits (475), Expect = 2e-47,   Method: Compositional matrix adjust.
 Identities = 86/137 (62%), Positives = 107/137 (78%)
 Frame = +1

Query: 649 VQQFILNLEQQMAEFKASLSPVIYDSLTGLMTSXXXXXXXXXXXXSTFNRLGGLQFDKEL 708
           VQ  I+ L+  +  FK SL+   YD+   L+T+            ++FNRLGGLQFDKEL
Sbjct: 1   VQSSIVTLDTMLTTFKNSLTSANYDNFVTLVTTEITVQLEKAVSKTSFNRLGGLQFDKEL 180

Query: 709 RSLIAYLTTVTTWTIRDKFARLSQMATILNLERVTEILDYWGANSGPLTWRLTPAEVRQV 768
           R+L+ YL++VTTWT+RDKFARL+QMATILNLERV+EI+DYWG NSGPLTWRLTPAEVRQ 
Sbjct: 181 RALVGYLSSVTTWTVRDKFARLTQMATILNLERVSEIMDYWGQNSGPLTWRLTPAEVRQT 360

Query: 769 LALRIDFRNEDIKRLRL 785
           L+LR DFR++DIKRL+L
Sbjct: 361 LSLRNDFRSDDIKRLKL 411
>13811
          Length = 496

 Score = 35.0 bits (79), Expect = 0.11,   Method: Compositional matrix adjust.
 Identities = 17/52 (32%), Positives = 31/52 (59%)
 Frame = +2

Query: 726 KFARLSQMATILNLERVTEILDYWGANSGPLTWRLTPAEVRQVLALRIDFRN 777
           K+A+ +++  +LN   + EI+D W    GPL   ++P E++Q+  +R  FR 
Sbjct: 245 KYAKFTEIQLVLN-GSLQEIVDRWADGMGPLAAEVSPNELKQM--IRALFRT 391
>12155
          Length = 563

 Score = 28.9 bits (63), Expect = 8.0,   Method: Compositional matrix adjust.
 Identities = 23/67 (34%), Positives = 34/67 (50%), Gaps = 4/67 (5%)
 Frame = -2

Query: 275 LFEGIARIVETHQPIVETYYGPGRLFTLIKYLQVECDTQVEK----VVNKFIKQRDYHQQ 330
           +F+G  R +E H  I ++ Y       LIK L V   TQV K    +V+ FI +++    
Sbjct: 364 IFKGKGRNIECHFRIRQSLYQISSFEXLIKVLSVCQSTQVHKTS*TIVDLFITRKEN--- 194

Query: 331 FRLVQSN 337
             L+QSN
Sbjct: 193 -ELLQSN 176
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31541801|ref|NP_082934.2| RIKEN cDNA 1110018J12 [Mus
musculus]
         (780 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

20700                                                                 186   2e-47
23594                                                                  30   2.6  
01230                                                                  30   4.3  
03957                                                                  29   8.7  
>20700
          Length = 903

 Score =  186 bits (473), Expect = 2e-47,   Method: Compositional matrix adjust.
 Identities = 117/263 (44%), Positives = 168/263 (63%), Gaps = 18/263 (6%)
 Frame = +2

Query: 510 SPLSAECMLQYEKKAAAYMKSLRT-PLAESVPYGEAVANRRVLLSSTESREGLAQQVQQS 568
            P S   +  + + AA+Y+ SL + P  +SVP+  AV NR+ LLSS ES+EGLA+Q+   
Sbjct: 62  GPRSHPAVTDFRQTAASYLSSLNSRPKPDSVPHRVAVQNRKTLLSSAESKEGLAKQISVF 241

Query: 569 LEKISKLEQEKEHWMLEAQLAKIKLEKENQRIA------DRLRGTTS------AQLPGLA 616
            E++ KLEQEKEHW+LE QL KIK + E Q++       + LR +TS      A   G  
Sbjct: 242 QERVGKLEQEKEHWVLELQLLKIKYDNEQQKVKRMEQELEVLRNSTSGVGSSVASTAGSI 421

Query: 617 QEN---ATVPIASSQEEAAAKVLTE--PVQSTSLVGMLTRTPDSEAPDVESREDLIKSHY 671
           ++N    T+P +++    A+   +   P ++  L G L    ++   D E+RE LIK+H+
Sbjct: 422 EDNIDRMTLPTSTADRRTASTASSSSGPTEAPRL-GQLEMGGEAGGGDGETREQLIKAHF 598

Query: 672 MARIAELTSQLQLADSKSVHFYAECRALSKRLALAEKSKETLTEEMRLASQNISRLQDEL 731
             RI ++T QLQLADSK+V F+AE RAL K+L LAE++K T  +E++ ASQ++++L+DEL
Sbjct: 599 TQRINDMTLQLQLADSKAVQFHAEVRALHKQLRLAERAKGTAEDELKAASQSMAQLKDEL 778

Query: 732 MTTKRSYEDQLSMMSDHLCSMNE 754
            TT RSYE QLSMMS+HL  MNE
Sbjct: 779 QTTTRSYEGQLSMMSEHLAGMNE 847
>23594
          Length = 1662

 Score = 30.4 bits (67), Expect = 2.6,   Method: Compositional matrix adjust.
 Identities = 18/61 (29%), Positives = 31/61 (50%)
 Frame = -2

Query: 664 EDLIKSHYMARIAELTSQLQLADSKSVHFYAECRALSKRLALAEKSKETLTEEMRLASQN 723
           ++L+  H++  +    S L    + +VH  A   A+   L L  KS +TLT+E+ L +  
Sbjct: 581 QNLVDYHHVLDLVPAISHLYFTHAITVHLSAVQNAVLMALGLQCKSVDTLTKELDLPATQ 402

Query: 724 I 724
           I
Sbjct: 401 I 399
>01230
          Length = 2578

 Score = 29.6 bits (65), Expect = 4.3,   Method: Compositional matrix adjust.
 Identities = 18/61 (29%), Positives = 31/61 (50%)
 Frame = -3

Query: 664 EDLIKSHYMARIAELTSQLQLADSKSVHFYAECRALSKRLALAEKSKETLTEEMRLASQN 723
           ++L+  H++  +    S L    + +VH  A   A+   L L  KS +TLT+E+ L +  
Sbjct: 944 QNLVDYHHVLDLVPAISHLYFTHAITVHLSAVQNAVLMALGLQCKSVDTLTKELDLPATQ 765

Query: 724 I 724
           I
Sbjct: 764 I 762
>03957
          Length = 908

 Score = 28.9 bits (63), Expect = 8.7,   Method: Compositional matrix adjust.
 Identities = 23/91 (25%), Positives = 39/91 (42%), Gaps = 4/91 (4%)
 Frame = +1

Query: 121 RLHIQFFEADEHH----RHVEAELRSRLATLETEAAQHQAVIDGLTRKYMETIEKLQSDK 176
           R+H ++F+   H       V   +      +ET+  +HQ  +D   R ++    K Q +K
Sbjct: 226 RIHYEYFDPGSHWCATCNMVCGHMFDYFKHIETK--KHQQKVDPFNRPWLVEAMKKQEEK 399

Query: 177 AKLEVKSQTLEKEAKECRLRTEECQLQLKNL 207
           AK + + Q    +     L T  CQ   +NL
Sbjct: 400 AKPQGQVQAAPIKGHTIYLFTVVCQTS*QNL 492
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6679573|ref|NP_033015.1| purine rich element binding
protein A [Mus musculus]
         (321 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

15221                                                                 185   2e-47
>15221
          Length = 1217

 Score =  185 bits (470), Expect = 2e-47,   Method: Compositional matrix adjust.
 Identities = 98/191 (51%), Positives = 133/191 (69%), Gaps = 11/191 (5%)
 Frame = -1

Query: 94   GNKSRLTLSMSVAVEFRDYLGDFIEHYAQLGPSQ---PPDLAQAQDEPRRALKSEFLVRE 150
            G KSRL L+MS A EFRDYL DF EHYA LGP+    PP+  +        LKSE +V++
Sbjct: 1217 GKKSRLLLAMSSAAEFRDYLTDFTEHYASLGPTNTESPPEDGK--------LKSETIVKD 1062

Query: 151  NRKYYMDLKENQRGRFLRI------RQTVNRGPGLGSTQGQTIALPAQGLIEFRDALAKL 204
            NR+YY+DLKENQRGRFLR+       QT+ RG      + Q IA+PAQG+IEFRDAL +L
Sbjct: 1061 NRRYYLDLKENQRGRFLRVVCYEQVSQTIPRG----GPRSQ-IAIPAQGMIEFRDALTEL 897

Query: 205  IDDYGVE-EEPA-ELPEGTSLTVDNKRFFFDVGSNKYGVFMRVSEVKPTYRNSITVPYKV 262
            +D++G + +EP  ELPE  S+ V+NK F+FDVGSN+ GV++RVSEV+  +R ++T+P + 
Sbjct: 896  LDEFGTDDQEPQNELPESRSMRVENKMFYFDVGSNRRGVYLRVSEVRNNFRTAVTIPERS 717

Query: 263  WAKFGHTFCKY 273
            WA+F     ++
Sbjct: 716  WARFRDVLSEF 684

 Score = 67.0 bits (162), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 41/156 (26%), Positives = 76/156 (48%), Gaps = 8/156 (5%)
 Frame = -1

Query: 59   ELASKRVDIQNKRFYLDVKQNAKGRFLKIA-------EVGAGGNKSRLTLSMSVAVEFRD 111
            +L S+ +   N+R+YLD+K+N +GRFL++         +  GG +S++ +     +EFRD
Sbjct: 1091 KLKSETIVKDNRRYYLDLKENQRGRFLRVVCYEQVSQTIPRGGPRSQIAIPAQGMIEFRD 912

Query: 112  YLGDFIEHYAQLGPSQPPDLAQAQDEPRRALKSEFLVR-ENRKYYMDLKENQRGRFLRIR 170
             L + ++ +                EP+  L     +R EN+ +Y D+  N+RG +LR+ 
Sbjct: 911  ALTELLDEF-----------GTDDQEPQNELPESRSMRVENKMFYFDVGSNRRGVYLRVS 765

Query: 171  QTVNRGPGLGSTQGQTIALPAQGLIEFRDALAKLID 206
            +  N            + +P +    FRD L++ +D
Sbjct: 764  EVRN-------NFRTAVTIPERSWARFRDVLSEFVD 678
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|30794390|ref|NP_082412.1| DEAH (Asp-Glu-Ala-His) box
polypeptide 36 [Mus musculus]
         (1001 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

09272                                                                 186   3e-47
19545                                                                 166   4e-41
12784                                                                 164   1e-40
03659                                                                 140   2e-33
17966                                                                 123   4e-28
19948                                                                 115   9e-26
18403                                                                  82   1e-15
20747                                                                  81   2e-15
35632                                                                  56   9e-08
02054                                                                  36   0.077
03718                                                                  30   6.9  
>09272
          Length = 890

 Score =  186 bits (473), Expect = 3e-47,   Method: Compositional matrix adjust.
 Identities = 102/285 (35%), Positives = 163/285 (57%), Gaps = 3/285 (1%)
 Frame = +2

Query: 513 LIIPLHSL-MPTVNQTQVFKKTPPGVRKIVIATNIAETSITIDDVVYVIDGGKIKETHFD 571
           LIIP   L +P+  QT++F+  PPG RK+VIATNIAETS+TI+ + YV+D G +K+  ++
Sbjct: 29  LIIPARLLRLPSEMQTRIFEPAPPGSRKVVIATNIAETSLTINGIYYVVDPGFVKQNVYN 208

Query: 572 TQNNISTMSAEWVSKANAKQRKGRAGRVQPGHCYHLYN--GLRASLLDDYQLPEILRTPL 629
           ++  +  +    +S+A AKQR GRAGR  PG CY LY     R  +L    +PEI RT L
Sbjct: 209 SKTGMDQLIVTPISQAQAKQRAGRAGRTGPGKCYRLYTERAYRDEMLPT-NVPEIQRTNL 385

Query: 630 EELCLQIKILRLGGIAYFLSRLMDPPSNEAVVLSIKHLMELSALDKQEELTPLGVHLARL 689
               L +K + +  +  F    MD P  + ++ +++ L  LSALD +  LT LG  +A  
Sbjct: 386 ASTVLSLKAMGINDLLAF--DFMDSPPMQTLISAMEQLHALSALDDEGLLTRLGRRMAEF 559

Query: 690 PVEPHIGKMILFGALFCCLDPVLTIAASLSFKDPFVIPLGKEKIADARRKELAKETRSDH 749
           P+EP + KM++      C D +LTI + LS ++ F  P  K+ +AD ++ +   +   DH
Sbjct: 560 PLEPMLSKMLIMSVHLACSDEILTIVSMLSVQNVFYRPKDKQALADQKKAKF-HQPEGDH 736

Query: 750 LTVVNAFEGWEEAKRRGFRYEKDYCWEYFLSSNTLQMLHNMKGQF 794
           LT+++ +  W+  K     +   +C+E F+   TL+   +++ Q 
Sbjct: 737 LTLLSVYNSWKNNK-----FSSPWCYENFVQIRTLKRAQDVRKQM 856
>19545
          Length = 519

 Score =  166 bits (420), Expect = 4e-41,   Method: Composition-based stats.
 Identities = 73/167 (43%), Positives = 118/167 (70%)
 Frame = +2

Query: 246 KGSACRIVCTQPRRISAISVAERVATERAESCGNGNSTGYQIRLQSRLPRKQGSILYCTT 305
           +G+ C I+ TQPRRISA+S+AERVA ER+E  GN  S GY +R ++ +PR  G++LYCT 
Sbjct: 2   RGAFCNIIVTQPRRISAVSIAERVAEERSEMLGN--SVGYSVRFETVMPRPYGAMLYCTV 175

Query: 306 GIILQWLQSDSRLSSVSHIVLDEIHERNLQSDVLMTVIKDLLHFRSDLKVILMSATLNAE 365
           G +L+ L+    L  VSH+++DEIHER++ +D L+ +++D++    DL+V+LMSAT++  
Sbjct: 176 GTLLRKLEGG--LRGVSHVIVDEIHERDINTDFLLVLLRDMVRAYPDLRVLLMSATVDTT 349

Query: 366 KFSEYFGNCPMIHIPGFTFPVVEYLLEDIIEKIRYVPDQKEHRSQFK 412
            F++YFG+C ++ + G  +PV EY LED I+ + +VP   + + + +
Sbjct: 350 LFTDYFGSCTVVEVYGRVYPVQEYYLEDCIQMLNFVPAPNDRKRKMR 490
>12784
          Length = 2199

 Score =  164 bits (416), Expect = 1e-40,   Method: Compositional matrix adjust.
 Identities = 109/356 (30%), Positives = 188/356 (52%), Gaps = 4/356 (1%)
 Frame = -1

Query: 538  RKIVIATNIAETSITIDDVVYVIDGGKIKETHFDTQNNISTMSAEWVSKANAKQRKGRAG 597
            RK+V++TNIAETS+TID VV+VID G  K+  ++ +  + ++    +SKA+A+QR GRAG
Sbjct: 2199 RKVVVSTNIAETSLTIDGVVFVIDPGFAKQKVYNPRIRVESLLVTAISKASAQQRAGRAG 2020

Query: 598  RVQPGHCYHLYN-GLRASLLDDYQLPEILRTPLEELCLQIKILRLGGIAYFLSRLMDPPS 656
            R +PG C+ LY        + +   PEILR+ L  + LQ+K L +  + +F    MDPP+
Sbjct: 2019 RTRPGKCFRLYTEKAYTQEMQENTYPEILRSNLGSVVLQLKKLGIDDLVHF--DFMDPPA 1846

Query: 657  NEAVVLSIKHLMELSALDKQEELTPLGVHLARLPVEPHIGKMILFGALFCCLDPVLTIAA 716
             E ++ +++ L  L+ LD   ELT LG  +A  P++P + KM++      C + +L+I +
Sbjct: 1845 PETLMRALELLNYLAGLDDDGELTELGSMMAEFPLDPQLAKMVIASCDSNCSNEILSITS 1666

Query: 717  SLSFKDPFVIPLGKEKIADARRKELAKETRSDHLTVVNAFEGWEEAKRRGFRYEKDYCWE 776
             LS    FV P   +K AD  +   A     DHLT++N +  +++        +  +C++
Sbjct: 1665 MLSVPQCFVRPTEAKKAADEAKMRFA-HIDGDHLTLLNVYHAFKQNHE-----DPQWCYD 1504

Query: 777  YFLSSNTLQMLHNMKGQFAEHLLGAGFVSSRSPKDPKANINSDNEKIIKAVICAGLYPKV 836
             F++  +L+   N++ Q A   +   F   RS  +  +    D    I+  +  G + +V
Sbjct: 1503 NFINYRSLKSADNVRQQLAR--IMDRFNLRRSSTEFTSR---DYYLNIRRALVNGFFMQV 1339

Query: 837  AKIRLNLGKKRKMVKVHTKSDGLVSIHPKSVNVEQTDFHYNWLIYH---LKMRTSS 889
            A +      +R    +  K + +V +HP +V     D    W++Y+   L  +T+S
Sbjct: 1338 AHL------ERTGHYLTVKDNQVVQLHPSTV----LDHKPEWVLYNEFVLTTKTTS 1201
>03659
          Length = 1566

 Score =  140 bits (354), Expect = 2e-33,   Method: Compositional matrix adjust.
 Identities = 77/184 (41%), Positives = 115/184 (62%), Gaps = 1/184 (0%)
 Frame = -1

Query: 197 RKKLPSYGMQKELVNLINNHQVTVISGETGCGKTTQVTQFILDN-YIERGKGSACRIVCT 255
           R+ LP Y ++ EL+  ++++Q+ ++ GETG GKTTQ+TQ++ ++ Y  RGK     I CT
Sbjct: 528 RQGLPIYKLKDELLKAVHDNQILIVIGETGSGKTTQITQYLAESGYTTRGK-----IGCT 364

Query: 256 QPRRISAISVAERVATERAESCGNGNSTGYQIRLQSRLPRKQGSILYCTTGIILQWLQSD 315
           QPRR++A+SVA+RV+ E    C  G   GY IR +      +  I Y T G++L+    D
Sbjct: 363 QPRRVAAMSVAKRVSEEFG--CRLGQEVGYTIRFED-CTSPETKIKYMTDGMLLRECLID 193

Query: 316 SRLSSVSHIVLDEIHERNLQSDVLMTVIKDLLHFRSDLKVILMSATLNAEKFSEYFGNCP 375
             L   S ++LDE HER + +DVL  ++K  +  R DLK+I+ SATL+A KFS+YF   P
Sbjct: 192 RDLMQYSIVMLDEAHERTIHTDVLFGLLKQAVKKRPDLKLIVTSATLDAVKFSQYFFEAP 13

Query: 376 MIHI 379
           +  I
Sbjct: 12  IFTI 1
>17966
          Length = 424

 Score =  123 bits (309), Expect = 4e-28,   Method: Composition-based stats.
 Identities = 67/148 (45%), Positives = 91/148 (61%), Gaps = 8/148 (5%)
 Frame = -1

Query: 588 NAKQRKGRAGRVQPGHCYHLYNGLRASLLDDYQLPEI--------LRTPLEELCLQIKIL 639
           N +QR+GRAGRV+PG           S++    L E         +  PL EL L IK+L
Sbjct: 424 NLEQRRGRAGRVRPGFL---------SIVQSRPLRETGPAHNSGDIPHPLHELALSIKLL 272

Query: 640 RLGGIAYFLSRLMDPPSNEAVVLSIKHLMELSALDKQEELTPLGVHLARLPVEPHIGKMI 699
           RLG I+ FLS  ++PP  +AVV +   L  + ALD  +ELTPLG  LAR+P+EPH+GKMI
Sbjct: 271 RLGPISGFLSXAVEPPPIDAVVEAEATLRSMHALDSNDELTPLGRILARMPIEPHLGKMI 92

Query: 700 LFGALFCCLDPVLTIAASLSFKDPFVIP 727
           ++G +F   D + TIAAS +F +PF+ P
Sbjct: 91  IYGCIFYIGDAMCTIAASTTFPEPFITP 8
>19948
          Length = 466

 Score =  115 bits (288), Expect = 9e-26,   Method: Compositional matrix adjust.
 Identities = 57/130 (43%), Positives = 81/130 (62%)
 Frame = +1

Query: 456 QMMDDDKVDLNLIAALIRYIVLEEEDGAILVFLPGWDNISTLHDLLMSQVMFKSDKFLII 515
           +M+ + ++   L+ AL+RYI      GA+L FLPGW  I  +   L     F S K+ I+
Sbjct: 55  RMLPEKEISFELVEALLRYIQGLGIPGAVLFFLPGWSLIFMIQRHLQMSPEFGSSKYCIL 234

Query: 516 PLHSLMPTVNQTQVFKKTPPGVRKIVIATNIAETSITIDDVVYVIDGGKIKETHFDTQNN 575
           PLHS +P   Q +VF+  P GV KI+++TNIAETS+TI+DVVYVID  K+K   F + NN
Sbjct: 235 PLHSQIPREEQRKVFEPVPDGVTKIILSTNIAETSVTINDVVYVIDSCKVKMKLFTSHNN 414

Query: 576 ISTMSAEWVS 585
           ++  +  W S
Sbjct: 415 MTNYATVWAS 444
>18403
          Length = 434

 Score = 81.6 bits (200), Expect = 1e-15,   Method: Composition-based stats.
 Identities = 47/132 (35%), Positives = 73/132 (55%)
 Frame = +2

Query: 616 LDDYQLPEILRTPLEELCLQIKILRLGGIAYFLSRLMDPPSNEAVVLSIKHLMELSALDK 675
            + Y  PEI R PL+ L LQ+  + L  +  F    ++PP    +  S++ L E  AL  
Sbjct: 32  FEAYSTPEIQRVPLDSLVLQLISMGLPNVRKF--PFIEPPDLSTIENSVRFLKEQGALAG 205

Query: 676 QEELTPLGVHLARLPVEPHIGKMILFGALFCCLDPVLTIAASLSFKDPFVIPLGKEKIAD 735
            E LT +G  L+ LPV+  IGKM++ G++F  +DP+L+IAA++S + PF      +  A 
Sbjct: 206 DESLTAIGQMLSMLPVDVVIGKMLIMGSIFHMVDPILSIAAAMSVQSPFTGKAHIDHDAI 385

Query: 736 ARRKELAKETRS 747
           A RK L  +  +
Sbjct: 386 AARKSLESDMET 421
>20747
          Length = 444

 Score = 81.3 bits (199), Expect = 2e-15,   Method: Compositional matrix adjust.
 Identities = 53/143 (37%), Positives = 84/143 (58%), Gaps = 6/143 (4%)
 Frame = +1

Query: 227 CGKTTQVTQFILD-NYIERGKGSACRIVCTQPRRISAISVAERVATERAESCGNGNSTGY 285
            GKTTQV QF+ +  Y  +G      I  T+PRR++AIS+++RVA E   +        Y
Sbjct: 1   SGKTTQVPQFLYEAGYAHKG----GMIGVTEPRRVAAISMSQRVAEEMNLTS---REVSY 159

Query: 286 QIRLQSRLPRKQGSILYCTTGIILQWLQSDSRLSSVSHIVLDEIHERNLQSDVLMTVIKD 345
           QIR +  +      I + T G++L+ +Q D  LS  S I+LDE HER++ +D+L+ ++  
Sbjct: 160 QIRYEGNVT-PDTHIKFMTDGVLLREIQQDFVLSKYSVIILDEAHERSVFTDILIGLLSR 336

Query: 346 LLHFR-----SDLKVILMSATLN 363
           +  +R     S LK+++MSATL+
Sbjct: 337 IAPYRIKKNLSPLKLVIMSATLD 405
>35632
          Length = 627

 Score = 55.8 bits (133), Expect = 9e-08,   Method: Compositional matrix adjust.
 Identities = 32/126 (25%), Positives = 64/126 (50%), Gaps = 5/126 (3%)
 Frame = +1

Query: 678 ELTPLGVHLARLPVEPHIGKMILFGALFCCLDPVLTIAASLSFKDPFVIPLGKEKIADAR 737
           +LT +G  +A LPV+  IGK+++ G +F  L+  + I A+LS K  F  P      A   
Sbjct: 115 DLTFVGRVMADLPVDIRIGKLMILGYVFGLLEECIIIGAALSLKSIFATPFKSRLEAFMH 294

Query: 738 RKELAKETRSDHLTVVNAFEGWEEAK-----RRGFRYEKDYCWEYFLSSNTLQMLHNMKG 792
           + + +  + SD   +++A+  WE+ K     +R    E  +  ++F+ +  +  +H +  
Sbjct: 295 KYQWSSGSLSDCQAILHAYRVWEKCKELQEFKRTGMTENQWGMKHFIQTRRINEVHQLVR 474

Query: 793 QFAEHL 798
           + ++ L
Sbjct: 475 ELSQRL 492
>02054
          Length = 1110

 Score = 36.2 bits (82), Expect = 0.077,   Method: Compositional matrix adjust.
 Identities = 26/97 (26%), Positives = 41/97 (42%), Gaps = 2/97 (2%)
 Frame = -3

Query: 505 VMFKSDKFLIIPLHSLMPTVNQTQVFKKTPPGVRKIVIATNIAETSITID--DVVYVIDG 562
           ++ ++  F  IPLH  M    +     K     R I+IAT++A   + I   DVV  +D 
Sbjct: 586 LLLRNLGFTAIPLHGQMSQAKRLGSLNKFKSKDRSILIATDVASRGLDIPHVDVVLNLD- 410

Query: 563 GKIKETHFDTQNNISTMSAEWVSKANAKQRKGRAGRV 599
                        I T S +++ +     R GR+GR 
Sbjct: 409 -------------IPTHSKDYMHRVGRTARAGRSGRA 338
>03718
          Length = 568

 Score = 29.6 bits (65), Expect = 6.9,   Method: Composition-based stats.
 Identities = 17/58 (29%), Positives = 27/58 (46%)
 Frame = -1

Query: 253 VCTQPRRISAISVAERVATERAESCGNGNSTGYQIRLQSRLPRKQGSILYCTTGIILQ 310
           + TQP+  S+ S+ +   + R   CG    T Y + L   L RK  SI  C   ++ +
Sbjct: 214 ILTQPQLHSSSSITQSFHSHRQLGCGRAQVTCYHL-LPLLLSRKSRSISNCXRSVLFK 44
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31982483|ref|NP_031621.2|
calcium/calmodulin-dependent protein kinase II beta [Mus musculus]
         (542 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

15910                                                                 185   3e-47
01392                                                                 124   1e-28
12721                                                                 119   4e-27
03240                                                                 106   2e-23
01060                                                                 106   3e-23
01707                                                                 102   4e-22
30755                                                                 100   3e-21
13592                                                                  97   2e-20
18484                                                                  96   5e-20
09606                                                                  93   3e-19
14126                                                                  92   6e-19
17975                                                                  92   7e-19
14420                                                                  91   2e-18
26711                                                                  89   4e-18
21079                                                                  89   5e-18
00300                                                                  89   6e-18
21433                                                                  72   1e-16
13212                                                                  74   1e-13
01966                                                                  73   3e-13
09007                                                                  72   7e-13
00486                                                                  71   1e-12
28638                                                                  60   3e-12
29581                                                                  69   7e-12
31885                                                                  68   9e-12
01718                                                                  68   1e-11
38560                                                                  66   4e-11
13066                                                                  65   8e-11
27405                                                                  65   9e-11
26560                                                                  64   1e-10
12786                                                                  64   1e-10
06405                                                                  64   2e-10
19761                                                                  64   2e-10
00392                                                                  64   2e-10
18663                                                                  62   5e-10
18921                                                                  62   5e-10
04591                                                                  62   8e-10
36002                                                                  61   9e-10
21418                                                                  60   2e-09
20152                                                                  60   2e-09
01756                                                                  59   6e-09
21808                                                                  59   6e-09
31120                                                                  55   8e-08
20655                                                                  53   3e-07
02638                                                                  52   5e-07
17300                                                                  52   5e-07
11185                                                                  52   7e-07
32000                                                                  52   7e-07
19094                                                                  52   8e-07
04852                                                                  51   1e-06
03508                                                                  50   2e-06
27546                                                                  50   2e-06
27274                                                                  50   3e-06
04138                                                                  50   3e-06
00715                                                                  49   4e-06
17722                                                                  48   8e-06
14116                                                                  48   1e-05
31489                                                                  46   3e-05
28157                                                                  46   3e-05
07291                                                                  46   4e-05
11780                                                                  46   4e-05
19301                                                                  45   5e-05
25019                                                                  45   6e-05
11404                                                                  44   2e-04
29590                                                                  43   4e-04
07940                                                                  43   4e-04
32957                                                                  42   6e-04
18996                                                                  41   0.001
18481                                                                  41   0.001
01106                                                                  41   0.001
20773                                                                  40   0.002
37063                                                                  39   0.006
36481                                                                  39   0.007
17644                                                                  38   0.011
12672                                                                  38   0.011
18401                                                                  37   0.015
00394                                                                  37   0.015
18287                                                                  37   0.019
31789                                                                  37   0.020
29360                                                                  36   0.030
23319                                                                  36   0.038
00638                                                                  36   0.048
16708                                                                  35   0.081
37602                                                                  34   0.12 
14104                                                                  34   0.17 
26009                                                                  33   0.27 
17516                                                                  33   0.28 
03106                                                                  33   0.28 
07836                                                                  33   0.28 
32359                                                                  33   0.34 
20513                                                                  32   0.44 
15549                                                                  32   0.44 
20559                                                                  32   0.50 
16350                                                                  32   0.52 
08294                                                                  32   0.54 
13305                                                                  32   0.72 
21800                                                                  31   1.1  
03294                                                                  30   2.1  
33586                                                                  30   2.2  
31232                                                                  29   4.7  
13078                                                                  28   9.5  
>15910
          Length = 1361

 Score =  185 bits (470), Expect = 3e-47,   Method: Compositional matrix adjust.
 Identities = 96/207 (46%), Positives = 133/207 (64%)
 Frame = +2

Query: 97  ELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLA 156
           ELF+ IV R  Y+E DA+  I  IL  V + H  GVVHRDLKPENLL       + +KLA
Sbjct: 422 ELFDRIVTRGQYTEKDAARAISDILHGVQYIHANGVVHRDLKPENLLYECMTDDSKLKLA 601

Query: 157 DFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWD 216
           DFGL+  ++ + Q      GTPGY +PEVL+ + Y   VD+W+ GVI YILL GY PF+ 
Sbjct: 602 DFGLSRIIEPEVQM-STVCGTPGYCAPEVLKGDKYTPSVDMWSVGVIAYILLCGYEPFFA 778

Query: 217 EDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRS 276
           E++ ++Y++I  G Y F    W  ++  AK+++ ++L I+P KR+TA EAL+ PWV   +
Sbjct: 779 ENEFEMYRKIIKGEYKFDEEYWSEISENAKDVVRKLLVIDPKKRLTATEALRLPWVKGVA 958

Query: 277 TVASMMHRQETVECLKKFNARRKLKGA 303
           T  + M  + T+  LK+FNARRKLK A
Sbjct: 959 TKTTNM--EITMNKLKEFNARRKLKCA 1033
>01392
          Length = 1806

 Score =  124 bits (310), Expect = 1e-28,   Method: Compositional matrix adjust.
 Identities = 72/192 (37%), Positives = 100/192 (52%), Gaps = 25/192 (13%)
 Frame = -1

Query: 107  YYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLA--IEV 164
            +  E +AS  ++ I  A+   H  G+ HRDLKPEN+L         VK+ DF LA  I  
Sbjct: 1803 HLCEREASLVVRHIARALDFLHSKGIAHRDLKPENILCEHLDDVVPVKICDFDLASGISC 1624

Query: 165  QGDQQA---WFGFAGTPGYLSPEVLR-----KEAYGKPVDIWACGVILYILLVGYPPFWD 216
             GD           G+  Y++PEV+        +Y K  D+W+ G+ILYI+L GYPPF+ 
Sbjct: 1623 DGDGTKTPELLTPVGSAEYMAPEVVDAWVGDSFSYDKRCDLWSLGIILYIMLCGYPPFYG 1444

Query: 217  ---ED------------QHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRI 261
               ED            Q  L+  I+ G Y FPS EW +++  AK+LI  +L   P KR 
Sbjct: 1443 QCGEDCGWNRGEACHDCQDMLFNSIQDGHYKFPSQEWTSISSSAKDLIRHLLVREPRKRY 1264

Query: 262  TAHEALKHPWVC 273
            +A + LKHPW+C
Sbjct: 1263 SAADVLKHPWIC 1228
>12721
          Length = 821

 Score =  119 bits (297), Expect = 4e-27,   Method: Compositional matrix adjust.
 Identities = 78/258 (30%), Positives = 133/258 (51%), Gaps = 4/258 (1%)
 Frame = +1

Query: 10  FTDEYHLYEDIGKGAFSVVRRCVKLC-TGHEYASKIINTKKLSARDHHKLEREARICRLL 68
           F D++     IG+G+  +V  C+     G + A K ++ +K   R+   L  E  + R  
Sbjct: 91  FLDDFM---KIGEGSTGIV--CIATSRDGRQMAVKKMDLRKQQRRE--LLFNEVVVMRDY 249

Query: 69  KHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCH 128
            H NIV +++S       ++V + + GG L  DIV      E   +   +  L+A+   H
Sbjct: 250 HHPNIVEMYNSYLVNDELWVVMEFMEGGAL-TDIVTNNRMDEVQIATVCRACLKALAFLH 426

Query: 129 QMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRK 188
             GV+HRD+K +++LL+   K   VKL DFG   +V  D Q      GTP +++PEV+ +
Sbjct: 427 ANGVIHRDIKSDSILLSHDGK---VKLXDFGFCAQVTQDLQKRKSLVGTPYWMAPEVISR 597

Query: 189 EAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT---VTPEA 245
             YG  VDIW+ G+++  ++   PPF++E   +  ++I+    D P P+      ++P  
Sbjct: 598 LPYGPEVDIWSLGIMVMEMIDAEPPFFNEPPLQAMRRIR----DMPPPKLRNTHKISPRL 765

Query: 246 KNLINQMLTINPAKRITA 263
           +  I++ML  +P +R TA
Sbjct: 766 QGFIDRMLVRDPHQRATA 819
>03240
          Length = 1683

 Score =  106 bits (264), Expect = 2e-23,   Method: Compositional matrix adjust.
 Identities = 83/300 (27%), Positives = 129/300 (43%), Gaps = 55/300 (18%)
 Frame = -3

Query: 20   IGKGAFSVVRRCVKLCTGHEYASKIINTKKLSARD---HHKLEREARICRLLKHSNIVRL 76
            +G GAF  V  C K  TG  YA K +    +  R+   H K ER+  I     +  +V+L
Sbjct: 1267 LGVGAFGEVSLCRKNDTGMLYAMKTLRKSDVLKRNQVAHVKAERD--ILAEADNEWVVKL 1094

Query: 77   HDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRD 136
            + S  +  + Y V D V GG+L   ++  E   E  A   + ++++A+   H+MG +HRD
Sbjct: 1093 YYSFQDHNYLYFVMDYVPGGDLMGLLIRMEILDEPLARFYVAELVQAIESVHRMGFIHRD 914

Query: 137  LKPENLLLASKCKGAAVKLADFGLA-------------------------IEVQGDQQAW 171
            +KP+N+L+    +   +KL DFGL                          ++ Q D+Q  
Sbjct: 913  IKPDNILID---RNGHIKLTDFGLCTGFRWTHNSKYYQRDGTHARQDSMEVKCQLDEQCQ 743

Query: 172  -------------------FGFAGTPGYLSPEVL-RKEAYGKPVDIWACGVILYILLVGY 211
                                   GTP Y++PEVL R   Y    D W+ GVIL+ +LVG+
Sbjct: 742  CEILKPLERRRKREQRCLAHSLVGTPNYIAPEVLSRLGGYTSVCDWWSVGVILFEMLVGH 563

Query: 212  PPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLI-------NQMLTINPAKRITAH 264
            PPF+     +   ++         P    ++  AK+LI       +  L +N A  I  H
Sbjct: 562  PPFYANTPAETQYKVINWKDMLKIPRESNLSQPAKDLILRLCCGSDDRLGLNGAGEIKTH 383
>01060
          Length = 1800

 Score =  106 bits (264), Expect = 3e-23,   Method: Compositional matrix adjust.
 Identities = 84/298 (28%), Positives = 138/298 (46%), Gaps = 37/298 (12%)
 Frame = +1

Query: 17  YEDIGKGAFSVVRRCVKLCTGHEYASKIINTKKLSARDHHKLEREARICRLLKHSNIVRL 76
           ++ IG+G + VV +C    TG + A K I  +           RE  + R L+H+NIV L
Sbjct: 88  FQKIGEGTYGVVYKCRHRATGRKLAMKKIRLRGSEDGVPSSAIREIAMLRELRHTNIVCL 267

Query: 77  HDSISEEGFHYLVFDLVTG-----------GELFEDIVAREYYSEADASHCIQQILEAVL 125
            D I E+   +LVF+ ++            G + +  + + Y         + QI+  + 
Sbjct: 268 EDVIMEDERLFLVFEFLSMDLKMYIDKFPEGVVLDRRLVKSY---------VFQIVTGIX 420

Query: 126 HCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEV 185
            CHQ  +VHRDLKP+NLL+       A+K+ADFG+A       +A+     T  Y +PE+
Sbjct: 421 FCHQRRIVHRDLKPQNLLINHT---GAIKIADFGMARTFALPVRAYTHEVVTLWYRAPEI 591

Query: 186 LRKEA-YGKPVDIWACGVILYILLVGYPPFWDEDQ----HKLYQQI------------KA 228
           L   + Y  PVD+W+ G I   +L+  P F  + +     K+++ I            K 
Sbjct: 592 LMGASKYSTPVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIFRIIGTPTEQTWPEFHKL 771

Query: 229 GAYDFPSPEW------DTVT---PEAKNLINQMLTINPAKRITAHEALKHPWVCQRST 277
            A++   P W      +T+T       +LI + L  +PA+RI+  + L+H +     T
Sbjct: 772 PAFNGMFPLWKEGKLSETLTDLDSLGLDLIERTLKCDPAQRISCKKMLQHAYFLNVDT 945
>01707
          Length = 757

 Score =  102 bits (253), Expect = 4e-22,   Method: Compositional matrix adjust.
 Identities = 77/227 (33%), Positives = 108/227 (47%), Gaps = 12/227 (5%)
 Frame = +1

Query: 11  TDEYHLYEDIGK---GAFSVVRRCVKLCTGHEYASKIINTKKLSARDHHKL-----EREA 62
            D    YE IGK   G++ VV +C      ++  S+++  KK    +   L      RE 
Sbjct: 52  VDRMEKYEKIGKIGEGSYGVVFKC-----RNKETSQLVAIKKFVESEDDPLIKKIAMREI 216

Query: 63  RICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILE 122
           R+ + LKH N+VRL +    +   +LVFD V    L E         E      I Q L 
Sbjct: 217 RMLKQLKHPNLVRLIEVFRRKKRLHLVFDYVDHTLLNELDRYPRGLPEPMVKRIIYQTLL 396

Query: 123 AVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLS 182
           AV  CHQ   +HRD+KPEN+L+  +     VKL DFG A  + G    +  +  T  Y +
Sbjct: 397 AVNFCHQYNTIHRDVKPENILITRQ---GQVKLCDFGFARILTGPGDEYTDYVATRWYRA 567

Query: 183 PEVLRKEA-YGKPVDIWACGVILYILLVG---YPPFWDEDQHKLYQQ 225
           PE+L  +  YG PVD+WA G +   LL G   +P   D DQ  L ++
Sbjct: 568 PELLVGDTQYGPPVDVWAIGCVFAELLTGQALWPGRSDVDQLHLIRK 708
>30755
          Length = 1137

 Score = 99.8 bits (247), Expect = 3e-21,   Method: Compositional matrix adjust.
 Identities = 55/143 (38%), Positives = 81/143 (56%)
 Frame = +2

Query: 119 QILEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTP 178
           +I+ A+ + H  G+++RDLK ENLLL    K   +K+ADFGL  E     +    F GTP
Sbjct: 56  EIISALGYLHSQGIIYRDLKLENLLLD---KDGHIKVADFGLCKEDITYGRTTKTFCGTP 226

Query: 179 GYLSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEW 238
            YL+PEVL    YG+ VD W  GV++Y ++ G  PF++ D   L+  I      FP    
Sbjct: 227 EYLAPEVLDDNDYGRAVDWWGTGVVMYEMICGRLPFYNRDHDVLFTLILVEDVKFPR--- 397

Query: 239 DTVTPEAKNLINQMLTINPAKRI 261
             +T EAK+L++ +L  +P  R+
Sbjct: 398 -NITDEAKSLLSGLLAKDPRNRL 463
>13592
          Length = 980

 Score = 97.1 bits (240), Expect = 2e-20,   Method: Compositional matrix adjust.
 Identities = 77/263 (29%), Positives = 124/263 (47%), Gaps = 11/263 (4%)
 Frame = +2

Query: 20  IGKGAFSVVRRCVKLCTGHEYASKIINTKKLSARDHHKLEREARICRLLKHSNIVRLHDS 79
           IG+G F  V   V   TG   A K I  +    R    +  E +I   +KH N+VR +  
Sbjct: 8   IGQGRFGKVYTAVNNNTGELMAMKEIAIQPGETRALKNVAEELKILEGIKHKNLVRYY-G 184

Query: 80  ISEEGFHYLVF-DLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLK 138
           I       L+F +L + G L   +       EA +     Q+L  V   H+ G+VHRD+K
Sbjct: 185 IEVHREELLIFMELCSEGTLESLVELTGGLPEALSRRFTAQLLSGVAELHKHGIVHRDIK 364

Query: 139 PENLLLASKCKGAAVKLADFGLAIEVQ------GDQQAWFGFAGTPGYLSPEVLRK---E 189
             N+ L       ++KL DFG A+++Q      G+ Q   G+ GT  Y++PEV  K   +
Sbjct: 365 TANIFLVDGSN--SLKLGDFGSAVKIQAHTTVPGELQ---GYVGTQAYMAPEVFTKTNSD 529

Query: 190 AYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFP-SPEWDTVTPEAKNL 248
            +G+  DIW+ G ++  +  G  P W +         K G  + P +PE  +++ E  + 
Sbjct: 530 GHGRLADIWSVGCVVVEMASGKRP-WAQFDSNFQIMFKVGMGEKPQAPE--SLSQEGHDF 700

Query: 249 INQMLTINPAKRITAHEALKHPW 271
           I+  L  +P +R++A E L+  +
Sbjct: 701 IDHCLQHDPKQRLSAIELLEQNF 769
>18484
          Length = 635

 Score = 95.5 bits (236), Expect = 5e-20,   Method: Compositional matrix adjust.
 Identities = 52/154 (33%), Positives = 83/154 (53%)
 Frame = +1

Query: 108 YSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGD 167
           + E  A+    +I   +   H  G+++RDLK +N++L S+     +K+ADFG+  E    
Sbjct: 34  FKEPVAAFYAAEIAVGLFFLHDQGIIYRDLKLDNVMLDSE---GHIKIADFGMCKEGMTG 204

Query: 168 QQAWFGFAGTPGYLSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIK 227
                 F GTP Y++PE++  + Y K VD WA GV+L+ +L G PPF  ED+ +L+  I 
Sbjct: 205 DATTRTFCGTPDYIAPEIVLYQPYSKSVDWWAYGVLLFEMLAGQPPFDGEDEDELFSSIT 384

Query: 228 AGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRI 261
                +P      ++ EA +L   +L  NP KR+
Sbjct: 385 DHNVSYPK----AMSREAVSLCKGLLMKNPTKRL 474
>09606
          Length = 1300

 Score = 92.8 bits (229), Expect = 3e-19,   Method: Compositional matrix adjust.
 Identities = 69/285 (24%), Positives = 130/285 (45%), Gaps = 27/285 (9%)
 Frame = -3

Query: 12   DEYHLYEDIGKGAFSVVRRCVKLCTGHEYASKIINTKKLSARDHHKLEREARICRLLKHS 71
            + + LYE++GKG  S++ +  +  T +  A   I   K       ++    R+   + H 
Sbjct: 1115 ENFVLYEELGKGEHSIIYKGRRKGTINFVAIHCIEKCKRP-----EVTNTVRMTHDISHP 951

Query: 72   NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYY-SEADASHCIQQILEAVLHCHQM 130
            N+V+ H+        +LV +L TGG L  DI+A++++  E         ++  + + H +
Sbjct: 950  NVVQFHEWYETSNHLWLVVELCTGGSL-ADILAQDHHLPETSIRDFGIHLVTGLHYIHSL 774

Query: 131  GVVHRDLKPENLLLASKCKGAAVKLADFGLA-IEVQGDQQAWFGFA-------------- 175
            G++  DL+P  +LL +      +K ADFGL+ +E +  ++ +F FA              
Sbjct: 773  GILFHDLRPSKVLLDTS---GVLKFADFGLSKVEGENLEELFFKFAEAGDQWNIQSAEEM 603

Query: 176  -------GTPGYLSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKA 228
                   G+P Y++PEV +        D+WA G + Y +  G+PPF  E       ++  
Sbjct: 602  MKQVPTSGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFSGHPPFLGETYDITKDKVLN 423

Query: 229  GAYDFPSPEWDTV----TPEAKNLINQMLTINPAKRITAHEALKH 269
              +  P  +   +    +PE  NL+  +L  +  +R++    +KH
Sbjct: 422  KEFPLPKVKGSRLSAKPSPEFLNLLESLLQKDSTRRLSWASLVKH 288
>14126
          Length = 1265

 Score = 92.0 bits (227), Expect = 6e-19,   Method: Compositional matrix adjust.
 Identities = 88/303 (29%), Positives = 127/303 (41%), Gaps = 50/303 (16%)
 Frame = +3

Query: 20  IGKGAFSVVRRCVKLCTGHEY-ASKIINTKKLSARDHHKLEREARICRLLK---HSNIVR 75
           IG GA+  V +   L    E+ A K I              RE  + + L+   H N+VR
Sbjct: 213 IGNGAYGTVYKARDLRNQGEFVAMKRIRLNNTEEGMPMMAIREISMLKQLEQYEHPNVVR 392

Query: 76  L----HDSISEEG------FHYLVFDLVT----------GGELFEDIVAREYYSEADASH 115
           L    H++I++        F Y+  DL T          G +  +D++            
Sbjct: 393 LLDVSHNTITDREIRLNLVFEYIEHDLATYLAKCPSPGLGPDRIKDLML----------- 539

Query: 116 CIQQILEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFA 175
              Q+L  V   H   +VHRDLKP+NLL++   K   +KLADFGLA  +     A     
Sbjct: 540 ---QLLNGVDFLHSNRIVHRDLKPQNLLIS---KDGRLKLADFGLA-RIYSFHMALTTVV 698

Query: 176 GTPGYLSPEVLRKEAYGKPVDIWACGVILYIL---------------------LVGYPPF 214
            T  Y SPEVL +  YG  VDIW+CG I   L                     ++G PP 
Sbjct: 699 VTLWYRSPEVLMQAEYGTSVDIWSCGCIFAELFTRRALFKGSSEFDQLKKIFEVIGLPPA 878

Query: 215 --WDED---QHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITAHEALKH 269
             W E        ++           PE D   P+AK+L+ +ML     +RI++ E+L H
Sbjct: 879 GDWPEGVSVHRNSFRPTPPVPLQTLVPEMD---PQAKDLMEKMLVFKSGRRISSRESLLH 1049

Query: 270 PWV 272
           P++
Sbjct: 1050PYL 1058
>17975
          Length = 449

 Score = 91.7 bits (226), Expect = 7e-19,   Method: Composition-based stats.
 Identities = 51/138 (36%), Positives = 81/138 (58%), Gaps = 1/138 (0%)
 Frame = +3

Query: 25  FSVVRRCVKLCTGHEYASKIINTKKLSARDHHKLEREARICRLLKHSNIVRLHDSISEEG 84
           F+VV+    + TG + A K+I+  KL       L +E R  +L++H N+VRL++ I  + 
Sbjct: 6   FAVVKLARHVFTGEKVAVKVIDKTKLDEVSRSHLFQEVRCMKLVQHPNVVRLYEVIDTQT 185

Query: 85  FHYLVFDLVTGGELFEDIVARE-YYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLL 143
             YL+ +L  GG++++ I+       E  A    +QI+EA+ +CH++ VVHRDLKPEN++
Sbjct: 186 KLYLILELGDGGDMYDYIMRHSGGLEEKLAKRYFRQIVEAISYCHKLHVVHRDLKPENVV 365

Query: 144 LASKCKGAAVKLADFGLA 161
                K   VKL DFG +
Sbjct: 366 FFE--KPGLVKLTDFGFS 413
>14420
          Length = 528

 Score = 90.5 bits (223), Expect = 2e-18,   Method: Compositional matrix adjust.
 Identities = 56/175 (32%), Positives = 94/175 (53%), Gaps = 3/175 (1%)
 Frame = +2

Query: 47  TKKLSARDHHKLE-REARICRLLKHSNIVRLHDS--ISEEGFHYLVFDLVTGGELFEDIV 103
           T  LS +   +L   E  + R  ++ NIV   DS  + EE   ++V + + GG L  D+V
Sbjct: 5   TMNLSQQPKKELIINEILVMRENQNPNIVNYLDSYLVGEE--LWVVMEFLAGGSL-TDVV 175

Query: 104 AREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIE 163
                 E   +   ++ L+A+   H+  V+HRD+K +N+LL       +VKL DFG   +
Sbjct: 176 TETCMDEGQIAAVCRECLQALEFLHENQVIHRDIKSDNILLGMD---GSVKLTDFGFCAQ 346

Query: 164 VQGDQQAWFGFAGTPGYLSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDED 218
           +  +Q       GTP +++PEV+ ++ YG  VDIW+ GV+   ++ G PP+ +E+
Sbjct: 347 LSPEQSKRSTMVGTPYWMAPEVVTRKQYGPTVDIWSLGVMCIEMIEGEPPYLNEN 511
>26711
          Length = 405

 Score = 89.4 bits (220), Expect = 4e-18,   Method: Composition-based stats.
 Identities = 49/134 (36%), Positives = 76/134 (56%), Gaps = 1/134 (0%)
 Frame = -2

Query: 117 IQQILEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAG 176
           ++Q+L+ + H H  GVVH DLKP NLLL+   K  +V+L DFGLA ++   Q+ +    G
Sbjct: 398 VKQVLDILQHVHAQGVVHMDLKPSNLLLSGD-KLDSVQLIDFGLARKLYPPQETFLNH-G 225

Query: 177 TPGYLSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFP-S 235
           TPG+ SPE L  +      D+W  GV+ YILL G  PF  +   +  ++ +   + F   
Sbjct: 224 TPGFTSPEALDVKPISTASDVWGVGVLAYILLSGQSPFQADSATESLKKTQTCDWSFDVC 45

Query: 236 PEWDTVTPEAKNLI 249
           P +  ++ +AK+ I
Sbjct: 44  PSFSNMSQDAKDFI 3
>21079
          Length = 878

 Score = 88.6 bits (218), Expect = 5e-18,   Method: Compositional matrix adjust.
 Identities = 54/147 (36%), Positives = 78/147 (53%), Gaps = 3/147 (2%)
 Frame = +1

Query: 70  HSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREY-YSEADASHCIQQILEAVLHCH 128
           H  ++ L D+        LV + V  GELFE ++  ++  +E D  H ++QI   V + H
Sbjct: 1   HPKLLMLWDAFEAPRTMVLVMEFVGAGELFERVIRDDFVLTERDCVHFVRQICSGVGYMH 180

Query: 129 QMGVVHRDLKPENLLLASKCKGAAVKLADFGLA-IEVQGDQ-QAWFGFAGTPGYLSPEVL 186
              ++H DLKPEN+L  S      +K+ DFGLA     GD  Q  FG   TP +++PEV+
Sbjct: 181 TQSILHLDLKPENVLCVSD-NSNQIKIIDFGLARFYKPGDSLQVLFG---TPEFIAPEVV 348

Query: 187 RKEAYGKPVDIWACGVILYILLVGYPP 213
             +      D+W+ GVI YILL G  P
Sbjct: 349 NYDEINFTTDMWSIGVICYILLSGLSP 429
>00300
          Length = 2318

 Score = 88.6 bits (218), Expect = 6e-18,   Method: Compositional matrix adjust.
 Identities = 68/259 (26%), Positives = 123/259 (47%), Gaps = 7/259 (2%)
 Frame = -1

Query: 20   IGKGAFSVVRRCVKLCTGHEYASKIINTKKLSARDHHKLEREARICRLLKHSNIVRLHDS 79
            IG+G F  V   V + TG   A K +  +    +   ++  E +I   ++H N+V+ +  
Sbjct: 1634 IGEGQFGKVYTAVNMSTGELMALKEMKFQPNDLQQLREMCDEIKIFEGIQHENLVKYYGV 1455

Query: 80   ISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKP 139
               +    +  +    G + E   A+    E       ++I+ AV H H+  +VHRD+K 
Sbjct: 1454 EVHKDEMLMFMEYCDTGTIEE--AAKMGLPEYLIRRYTREIVLAVNHLHENSIVHRDIKG 1281

Query: 140  ENLLLASKCKGAAVKLADFGLAIEVQGDQQA---WFGFAGTPGYLSPEVLRKE---AYGK 193
             N+ L S      VKL DFG +++++        +    GT  Y++PEV  +     YG+
Sbjct: 1280 ANIFLTSN---GHVKLGDFGCSVKLKSHTTMPGEFHNLVGTTAYMAPEVFTQNDQGGYGR 1110

Query: 194  PVDIWACGVILYILLVGYPPFWDEDQHKLYQQI-KAGAYDFPSPEWDTVTPEAKNLINQM 252
              DIW+ G ++  +  G  P+ D D +  YQ + K G    P+   D+++ E K+ ++ +
Sbjct: 1109 AADIWSLGCVVIEMATGKRPWHDLDNN--YQIMYKVGIGHKPAVP-DSLSVEGKHFLDLI 939

Query: 253  LTINPAKRITAHEALKHPW 271
            +  +PA+R  A + L H +
Sbjct: 938  MCHDPAQRALASQLLDHTF 882
>21433
          Length = 590

 Score = 72.4 bits (176), Expect(2) = 1e-16,   Method: Compositional matrix adjust.
 Identities = 49/142 (34%), Positives = 75/142 (52%), Gaps = 5/142 (3%)
 Frame = +2

Query: 117 IQQILEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAG 176
           I Q+  A+ +CH   V+HRD+KPENLLL  K     +K+ADFG ++     ++      G
Sbjct: 185 IYQLSSALEYCHYRKVIHRDIKPENLLLGLK---GDLKIADFGWSVHAPSSRRT--TMCG 349

Query: 177 TPGYLSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSP 236
           T  YL PE++  + + + VD+W+ GV+ Y  LVG PP          +          SP
Sbjct: 350 TLDYLPPEMVEGKTHDENVDLWSLGVLCYEFLVGTPPL---------RPSPTRPPTPASP 502

Query: 237 EWDT-----VTPEAKNLINQML 253
            W +     VTP A++LI+++L
Sbjct: 503 RWTSGSPSIVTPGARDLISKLL 568

 Score = 32.0 bits (71), Expect(2) = 1e-16,   Method: Compositional matrix adjust.
 Identities = 15/47 (31%), Positives = 27/47 (57%)
 Frame = +3

Query: 56  HKLEREARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDI 102
           H+L RE  I   L+H NI+R+     ++   YL+ +    GEL++++
Sbjct: 3   HQLRREIEIQSHLRHDNILRMFGYFHDKTRVYLILEFAPKGELYKEL 143
>13212
          Length = 1067

 Score = 73.9 bits (180), Expect = 1e-13,   Method: Compositional matrix adjust.
 Identities = 64/199 (32%), Positives = 98/199 (49%), Gaps = 10/199 (5%)
 Frame = -1

Query: 89   VFDLVTGGELFEDIVAREY-YSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASK 147
            VF ++  G L   +V  E   +EA   +   ++  A+   H+  V+HRD+K  N+LL   
Sbjct: 1049 VFRVLWWGALDSIMVDLEKPMTEAQICYVCHEMCMALDFLHRHHVIHRDIKAGNVLLTI- 873

Query: 148  CKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEV-----LRKEAYGKPVDIWACGV 202
                 VKLADFG++ +    QQ    F GTP +++PEV     L+   Y    DIW+ GV
Sbjct: 872  --DGEVKLADFGVSAKNTQTQQKRDTFIGTPYWMAPEVVLCETLKDTPYDFKADIWSLGV 699

Query: 203  ILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPE----WDTVTPEAKNLINQMLTINPA 258
             L       PP  +++ H +   IK    D P+ E    W  +    K+ I + L  +P 
Sbjct: 698  TLIEFAQIEPP--NKEMHPMRVLIKIHKSDPPTLEKPKKWTKL---FKDFIAKCLVKDPN 534

Query: 259  KRITAHEALKHPWVCQRST 277
             R TA E L+HP++ +R+T
Sbjct: 533  LRPTAAELLEHPFM-KRAT 480
>01966
          Length = 1735

 Score = 72.8 bits (177), Expect = 3e-13,   Method: Compositional matrix adjust.
 Identities = 58/190 (30%), Positives = 86/190 (45%), Gaps = 14/190 (7%)
 Frame = -1

Query: 28   VRR---CVKLCTGHEYASKIINTKKLSARDHHKLEREARICRLLKHSNIVRLHDSISEEG 84
            VRR   C    TG + A K I  +           RE  + R L+H+NIV L D I E+ 
Sbjct: 1672 VRRGL*CRHRATGRKLAMKKIRLRGSEDGVPSSAIREIAMLRELRHTNIVCLEDVIMEDE 1493

Query: 85   FHYLVFDLVTG-----------GELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVV 133
              +LVF+ ++            G + +  + + Y         + QI+  +  CHQ  +V
Sbjct: 1492 RLFLVFEFLSMDLKMYIDKFPEGVVLDRRLVKSY---------VFQIVTGINFCHQRRIV 1340

Query: 134  HRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKEAYGK 193
            HRDLKP+NLL+       A+K+ADFG+A       +A+     T  Y +PE+L       
Sbjct: 1339 HRDLKPQNLLINHT---GAIKIADFGMARTFALPVRAYTHEVVTLWYRAPEILMGPQSTP 1169

Query: 194  PVDIWACGVI 203
            P   W CG +
Sbjct: 1168 PX--WTCGAL 1145

 Score = 32.0 bits (71), Expect = 0.70,   Method: Compositional matrix adjust.
 Identities = 28/112 (25%), Positives = 49/112 (43%), Gaps = 25/112 (22%)
 Frame = -3

Query: 191  YGKPVDIWACGVILYILLVGYPPFWDEDQ----HKLYQQI------------KAGAYDFP 234
            Y  PVD+W+ G I   +L+  P F  + +     K+++ I            K  A++  
Sbjct: 1175 YSTPVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIFRIIGTPTEQTWPEFHKLPAFNGM 996

Query: 235  SPEW------DTVT---PEAKNLINQMLTINPAKRITAHEALKHPWVCQRST 277
             P W      +T+T       +LI + L  +PA+RI+  + L+H +     T
Sbjct: 995  FPLWKEGKLSETLTDLDSLGLDLIERTLKCDPAQRISCKKMLQHAYFLNVDT 840
>09007
          Length = 1440

 Score = 71.6 bits (174), Expect = 7e-13,   Method: Compositional matrix adjust.
 Identities = 57/226 (25%), Positives = 105/226 (46%), Gaps = 13/226 (5%)
 Frame = -1

Query: 16  LYEDIGKGAFSVVRRCVKLCTGHE---YASKIINTKKLSARDHHKLEREARICRLLKHSN 72
           L + +G+G F  VR+ +      E    A K ++  K+  +D  +  +E  I ++L H N
Sbjct: 867 LSKSLGQGHFGTVRQAIWTAESGEKVQVAVKCLSKDKIH-KDGQEFLKETAIMQMLDHEN 691

Query: 73  IVRLHDSISEEGFH-YLVFDLVTGGELFE---DIVAREYYSEADASHCIQQILEAVLHCH 128
           IVR++  + + G    LV +L     L E   ++ AR  +S        QQ+ + + +  
Sbjct: 690 IVRVYGVVMDNGADIMLVTELAPMRSLLECVKEVSARVDFSVPRLCDFSQQVCDGMSYLE 511

Query: 129 QMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAW-----FGFAGTPGYLSP 183
              +VHRDL   N+LL SK K   VK++D G++  +   ++ +             + +P
Sbjct: 510 SKRLVHRDLAARNILLFSKSK---VKISDVGVSGALGAGKEYYQSQQTIHLQNAVAWCAP 340

Query: 184 EVLRKEAYGKPVDIWACGVILYILLV-GYPPFWDEDQHKLYQQIKA 228
           E  R   +    D+WA GV+L+     G+ P+   +  ++ + + A
Sbjct: 339 ESFRNLCFSSASDVWAFGVLLWEFFTHGFQPWAGLNGQQIMEAVDA 202
>00486
          Length = 797

 Score = 70.9 bits (172), Expect = 1e-12,   Method: Compositional matrix adjust.
 Identities = 34/88 (38%), Positives = 53/88 (60%)
 Frame = -2

Query: 174 FAGTPGYLSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDF 233
           F GT  Y++PE+L +  +GK VD W+ G ++Y +L G PPF  E++ K   +I  G  + 
Sbjct: 778 FCGTIEYMAPEILTRTGHGKAVDWWSLGALMYDMLTGSPPFTAENRKKTIDKILKGKLNL 599

Query: 234 PSPEWDTVTPEAKNLINQMLTINPAKRI 261
           P      +T EA+ LI ++L  NPA+R+
Sbjct: 598 PP----YLTNEARGLIKKLLRKNPAERL 527
>28638
          Length = 1458

 Score = 60.5 bits (145), Expect(2) = 3e-12,   Method: Compositional matrix adjust.
 Identities = 36/99 (36%), Positives = 56/99 (56%), Gaps = 2/99 (2%)
 Frame = -1

Query: 118 QQILEAVLHCH--QMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFA 175
           QQ+  A+L     +M ++H DLKPEN+LL +  K +A+K+ DFG + ++    Q  + + 
Sbjct: 816 QQLCTALLFLATPEMNIIHCDLKPENILLCNP-KRSAIKIVDFGSSCQLG---QRIYQYI 649

Query: 176 GTPGYLSPEVLRKEAYGKPVDIWACGVILYILLVGYPPF 214
            +  Y SPEVL    Y   +D+W+ G IL  +  G PP 
Sbjct: 648 QSRFYRSPEVLLGVPYDLAIDMWSLGCILVEMHTGEPPL 532

 Score = 28.9 bits (63), Expect(2) = 3e-12,   Method: Compositional matrix adjust.
 Identities = 26/97 (26%), Positives = 40/97 (41%), Gaps = 12/97 (12%)
 Frame = -3

Query: 9    RFTDEYHLYEDIGKGAFSVVRRCVKLCTGHEYASKIINTKK------------LSARDHH 56
            ++ D Y +   IGKG+F  V +        + A KII  KK            L   + H
Sbjct: 1156 KWLDRYEIDSLIGKGSFGQVVKAYDHGDQEQVAIKIIKNKKPFLNQAQIEVKLLELMNRH 977

Query: 57   KLEREARICRLLKHSNIVRLHDSISEEGFHYLVFDLV 93
              +    I RL +H  + R H  +  E   Y ++DL+
Sbjct: 976  DADNXYYIVRLKRHF-MFRNHLCLVFELLSYNLYDLL 869
>29581
          Length = 1278

 Score = 68.6 bits (166), Expect = 7e-12,   Method: Compositional matrix adjust.
 Identities = 70/256 (27%), Positives = 113/256 (44%), Gaps = 39/256 (15%)
 Frame = -2

Query: 68   LKHSNIVRLHDSISEEGFH--YLVFDLVTG--GELFEDIVAREYYSEADASHCIQQILEA 123
            L+H NIV+L + +  +     +LV +        L +++ A   +SE+     + Q+L+ 
Sbjct: 1184 LRHQNIVQLQEVVVGKSLDSLFLVMEYCEQDLASLLDNMPAP--FSESQVKCIVLQLLKG 1011

Query: 124  VLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSP 183
            + + H+  ++HRDLK  NLL+  K     VK+ADFGLA      Q+       T  Y +P
Sbjct: 1010 LRYLHEAFIIHRDLKVSNLLMTDK---GCVKIADFGLARNYGKPQKPMTPKVVTLWYRAP 840

Query: 184  EVL-RKEAYGKPVDIWACGVILYILLVGYPPFW----DEDQHKLYQQ--------IKAGA 230
            E+L   + +   +D+W+ G IL  LL G+ P      D  Q +L  +        I  G 
Sbjct: 839  ELLFGSKTHSTAIDMWSAGCILGELL-GHKPLMPGRSDLQQIELIMELLGTPNDTIWPGF 663

Query: 231  YDFPSPEWDTVTPEAKN---------------LINQMLTINPAKRITAHEALKH------ 269
               P+ E  T+  +  N               L+N +   +P KR TA + L+H      
Sbjct: 662  SQLPAFEQFTLKKQPYNNLRHTFPWLSESGIRLLNGLFMYHPQKRATAEDCLEHSYFKEQ 483

Query: 270  PWVCQRSTVASM-MHR 284
            P+ C    + S   HR
Sbjct: 482  PYPCDPEFMPSFPQHR 435
>31885
          Length = 529

 Score = 68.2 bits (165), Expect = 9e-12,   Method: Compositional matrix adjust.
 Identities = 46/152 (30%), Positives = 75/152 (49%), Gaps = 5/152 (3%)
 Frame = -2

Query: 68  LKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHC 127
           L H  +V L  +  +E   ++V DL  GG+L   +     + E      + Q+   + + 
Sbjct: 501 LDHPFLVNLWYAFQDEEDLFMVVDLFLGGDLRYHMQQEVSFREDCVKFYLCQLALVLDYL 322

Query: 128 HQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVL- 186
               +VHRD+KP+N+LL  +       + DF +A +++ D+ A    +GT  Y++PEV  
Sbjct: 321 RSQKIVHRDIKPDNILLDEQ---GHCHVTDFNIATQLEDDELA-TSTSGTRPYMAPEVYG 154

Query: 187 ----RKEAYGKPVDIWACGVILYILLVGYPPF 214
                +  YG PVD W+ GV L+ LL    PF
Sbjct: 153 VAINERRGYGFPVDWWSLGVSLFELLKKRRPF 58
>01718
          Length = 959

 Score = 67.8 bits (164), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 56/202 (27%), Positives = 96/202 (47%), Gaps = 5/202 (2%)
 Frame = +3

Query: 8   TRFTDEYHLYEDIGKGAFSVVRRCVKLCTGHEYASKIINTKKLSARDHHKLEREARICRL 67
           TR  D   + E IG G FS V +     TG   A K+ NT      + H + RE ++   
Sbjct: 141 TRLDD--FICEKIGAGFFSEVFKVTHRITGQVMALKM-NT---MTSNRHNMLREVQLLNR 302

Query: 68  LKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQIL---EAV 124
           L+H+NI+R       EG  + + + +  G L + +  ++   E   +  IQ  L     +
Sbjct: 303 LQHANILRFMGVCVHEGQLHALTEYIPSGNLEQLLEKKD--EELPWTQRIQLTLGLARGL 476

Query: 125 LHCHQMGVVHRDLKPENLLLASKCK-GAAVKLADFGLAIEVQGD-QQAWFGFAGTPGYLS 182
            + H    +HRDL  +N+L+  +   G    +ADFGLA ++     +      G+P +++
Sbjct: 477 DYLHSTRFIHRDLTSKNILIRREDNHGYHAVIADFGLATKIPDPLDKEKLPTVGSPYWMA 656

Query: 183 PEVLRKEAYGKPVDIWACGVIL 204
           PEVL    Y +  D+++ G+I+
Sbjct: 657 PEVLNGHFYNERADLFSVGIIM 722
>38560
          Length = 479

 Score = 65.9 bits (159), Expect = 4e-11,   Method: Compositional matrix adjust.
 Identities = 44/121 (36%), Positives = 61/121 (50%), Gaps = 5/121 (4%)
 Frame = -3

Query: 176 GTPGYLSPEVLRKEAY-GKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFP 234
           G+P Y +PE++    Y G   DIW+ GV+LY LL GY PF DE    L Q+ +    +  
Sbjct: 399 GSPAYAAPELISGLEYLGSEADIWSMGVLLYALLCGYLPFDDEKXSHL*QKNQKRKDEV- 223

Query: 235 SPEWDTVTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTV----ASMMHRQETVEC 290
            PEW  ++ +   L+  ML  +P+ RIT    L H W+ Q   V    AS   R    +C
Sbjct: 222 -PEW--LSEDTTKLLEGMLQTDPSHRITIRRLLDHHWLNQGFNVPVEWASKYKRTLDEDC 52

Query: 291 L 291
           L
Sbjct: 51  L 49
>13066
          Length = 551

 Score = 64.7 bits (156), Expect = 8e-11,   Method: Compositional matrix adjust.
 Identities = 50/166 (30%), Positives = 75/166 (45%), Gaps = 5/166 (3%)
 Frame = +3

Query: 41  ASKIINTKKLSARDHHKL-EREARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELF 99
           A KII+ +K       K   RE  +   L H  I+++H  +     +++       G+L 
Sbjct: 63  ACKIIDKEKAPVDFVEKFFPRELDLLTKLDHPYIIQIHSILQRXPKNFIFMRFAERGDLL 242

Query: 100 EDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFG 159
             I    +  E  A     Q+  A+ + H   V HRDLK EN+LL+S      VKLADFG
Sbjct: 243 TYIQEVGFVKEKQAKIWFYQMTTALNYLHSYDVAHRDLKCENILLSSHFN---VKLADFG 413

Query: 160 LA---IEVQGDQQAWFGFAGTPGYLSPEVLRKEAYG-KPVDIWACG 201
            A   I   G++     + G+  Y +PE++    Y  K  D W+ G
Sbjct: 414 FACACITESGEKYMSRTYCGSAAYAAPEIVYGAPYAPKVADAWSLG 551
>27405
          Length = 532

 Score = 64.7 bits (156), Expect = 9e-11,   Method: Compositional matrix adjust.
 Identities = 51/179 (28%), Positives = 82/179 (45%), Gaps = 6/179 (3%)
 Frame = -3

Query: 24  AFSVVRRCVKLCTGHEYASKIINTKKLSARDHHKLEREARICRLLKHSN-----IVRLHD 78
            F  V  C K  TG  YA K ++ K++  +    L    RI   L  +      IV +  
Sbjct: 530 GFGEVYGCRKADTGKMYAMKCLDKKRIKMKGGETLALNERIMLSLVSTGEGSPFIVCMTY 351

Query: 79  SISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLK 138
           +         + DL+ GG+L   +     ++E +      +++  + H H   VV+RDLK
Sbjct: 350 AFQTPEKLCFILDLMNGGDLHYHLSQHGVFTEKEVRFYAAEVMLGLEHMHSRFVVYRDLK 171

Query: 139 PENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRK-EAYGKPVD 196
           P N+LL    +   V+++D GLA +    ++      GT GY++PEVL K +AY    D
Sbjct: 170 PANILLD---ENGHVRISDLGLACDFS--KKKPHASVGTHGYMAPEVLMKGQAYDSSAD 9
>26560
          Length = 398

 Score = 64.3 bits (155), Expect = 1e-10,   Method: Composition-based stats.
 Identities = 38/113 (33%), Positives = 63/113 (55%), Gaps = 1/113 (0%)
 Frame = -1

Query: 108 YSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGD 167
           ++E +      +++  + H H   VV+RDLKP N+LL    +   V+++D GLA +    
Sbjct: 365 FTEKEVRFYAAEVMLGLEHMHSRFVVYRDLKPANILLD---ENGHVRISDLGLACDFS-- 201

Query: 168 QQAWFGFAGTPGYLSPEVLRK-EAYGKPVDIWACGVILYILLVGYPPFWDEDQ 219
           ++      GT GY++PEVL K ++Y    D ++ G +LY LL G+ PF   +Q
Sbjct: 200 KKRPHASVGTHGYMAPEVLMKGQSYDSSADWFSFGCMLYKLLKGHSPFRQHNQ 42
>12786
          Length = 460

 Score = 64.3 bits (155), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 39/119 (32%), Positives = 56/119 (47%), Gaps = 22/119 (18%)
 Frame = -3

Query: 118 QQILEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWF--GFA 175
           +++L AV   H  GV+H DLKP N +L +      +KL DFG+A  +Q D+ +       
Sbjct: 389 REMLRAVKALHNEGVIHSDLKPANFMLVA----GNLKLIDFGIANTLQQDKTSVLKDSRV 222

Query: 176 GTPGYLSPEVLR--------------------KEAYGKPVDIWACGVILYILLVGYPPF 214
           GTP Y+SPE +                     K   G   D+W+ G ILY ++ G  PF
Sbjct: 221 GTPSYMSPEAIMAACDDSADDSMEEDGHRTKPKYKVGVRSDVWSLGCILYNMVYGRTPF 45
>06405
          Length = 1965

 Score = 63.9 bits (154), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 50/173 (28%), Positives = 80/173 (46%), Gaps = 4/173 (2%)
 Frame = +1

Query: 61  EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVA--REYYSEADASHCIQ 118
           EA I + +KH N+V+L    + E   Y+V + +  G L + + +  RE        +   
Sbjct: 397 EAAIMKEMKHPNLVQLLGVCTREPPFYIVTEFMPHGNLLDYLRSSTREENGPTALMYMAT 576

Query: 119 QILEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQ-QAWFGFAGT 177
           QI   + +      +HRDL   N L+A       VK+ADFGLA  ++ D   A  G    
Sbjct: 577 QIASGMAYLETKNFIHRDLAARNCLVAD---SNMVKVADFGLARLMKDDTYTAHIGAKFP 747

Query: 178 PGYLSPEVLRKEAYGKPVDIWACGVILYILLV-GYPPFWDEDQHKLYQQIKAG 229
             + +PE L    +    DIWA GV+L+ L   G  P+   +  ++Y  ++ G
Sbjct: 748 IKWTAPEGLAFNRFSTRSDIWAFGVLLWELATYGMSPYPGVELTEVYHLLERG 906
>19761
          Length = 473

 Score = 63.5 bits (153), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 43/130 (33%), Positives = 65/130 (50%)
 Frame = -3

Query: 125 LHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPE 184
           +H H   ++HRDLKP+N+ +  K     V+L D GLA ++ G         GT  YLSPE
Sbjct: 375 MHTHTPVILHRDLKPQNIYVTEK---GDVRLGDLGLARKLTGPADFATSQVGTIMYLSPE 205

Query: 185 VLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPE 244
           +L ++ Y    DIW+ G + Y  + G     +     L  Q+  G    P P  D  + E
Sbjct: 204 ILSQQPYNSKSDIWSLGCVFYD-ITGKKGSDEMGVMFLLVQVMGGR-KLPLP--DHYSQE 37

Query: 245 AKNLINQMLT 254
            ++ I++MLT
Sbjct: 36  FRDTISRMLT 7
>00392
          Length = 668

 Score = 63.5 bits (153), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 50/194 (25%), Positives = 95/194 (48%), Gaps = 8/194 (4%)
 Frame = +3

Query: 45  INTKKLSARDHHKLEREARICRLLKHSNIVRLHDSISEEGFH-----YLVFDLVTGGELF 99
           +  KK +  +  + + EA + + L+H NIVR  D   E          LV +L+T G L 
Sbjct: 33  LQDKKWNKAERQRFKEEAEMLKELQHPNIVRFFDYWEEHNHRNRKVIILVTELMTSGTLK 212

Query: 100 EDIVAREYYSEADASHCIQQILEAV--LHCHQMGVVHRDLKPENLLLASKCKGAAVKLAD 157
             +   +  +     +  +Q+L+ +  LH     V+HRDLK +N+ +       +VK+ D
Sbjct: 213 TYLKRFKKPNVKILKNWCRQVLKGLYFLHTRTPPVIHRDLKCDNIFITG--PTGSVKIGD 386

Query: 158 FGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWD- 216
            GLA     +Q       GTP +++PE + +E Y + VD++A G+ +  +     P+ + 
Sbjct: 387 LGLA--TLKNQSFAKSVIGTPEFMAPE-MYEEHYDEAVDVYAFGMCMLEMASSEYPYSEC 557

Query: 217 EDQHKLYQQIKAGA 230
            +  ++Y+++ +G 
Sbjct: 558 SNAAQIYKRVTSGV 599
>18663
          Length = 600

 Score = 62.4 bits (150), Expect = 5e-10,   Method: Compositional matrix adjust.
 Identities = 44/143 (30%), Positives = 70/143 (48%), Gaps = 16/143 (11%)
 Frame = +2

Query: 174 FAGTPGYLSPEVLRKEAYGKPVDIWACGVILYILLVGYPPF------WDEDQHK---LYQ 224
           F GTP Y++PE+LR E YG  VD WA GV+LY +L G  PF       + DQ+    L+Q
Sbjct: 8   FCGTPNYIAPEILRGEDYGFSVDWWALGVLLYEMLAGRSPFDIAGASENPDQNTEDYLFQ 187

Query: 225 QIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITAH------EALKHPWVCQRSTV 278
            I       P     +++ +A +++   L  NPA R+  H      + + HP+   +   
Sbjct: 188 VILEKTIRIPR----SLSVKAASVLKGFLNKNPADRLGCHRESAFMDIVNHPFF--KVID 349

Query: 279 ASMMHRQETVECLK-KFNARRKL 300
             M+ R++     K + ++ R L
Sbjct: 350 WEMLERKQVSPPFKPRLDSDRDL 418
>18921
          Length = 697

 Score = 62.4 bits (150), Expect = 5e-10,   Method: Compositional matrix adjust.
 Identities = 48/203 (23%), Positives = 94/203 (46%), Gaps = 1/203 (0%)
 Frame = +2

Query: 12  DEYHLYEDIGKGAFSVVRRCVKLCTGHEYASKIINTKKLSARDHHKLEREARICRLLKHS 71
           D + +   +G+G++  V + +   TG   A K +        D  ++ +E  I +     
Sbjct: 29  DVFDILGKLGEGSYGSVFKSLHKETGQVLAIKQVPVDT----DLQEIIKEISIMQQCDSK 196

Query: 72  NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAR-EYYSEADASHCIQQILEAVLHCHQM 130
            IV+ + S  +    ++V +    G + + +  R +   E + +  +   L+ + + H  
Sbjct: 197 YIVKYYGSYFKNTDLWIVMEYCGAGSVSDIMRLRNKTLVEREIATILYYTLKGLXYLHSR 376

Query: 131 GVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKEA 190
             +HRD+K  N+LL ++      KLADFG+A ++           GTP +++PEV+++  
Sbjct: 377 RKIHRDIKAGNILLNNE---GHAKLADFGVAGQLTDTMAKRNTVIGTPYWMAPEVIQEIG 547

Query: 191 YGKPVDIWACGVILYILLVGYPP 213
           Y    DIW+ G+    +  G PP
Sbjct: 548 YDCVADIWSLGITALEMAEGKPP 616
>04591
          Length = 1117

 Score = 61.6 bits (148), Expect = 8e-10,   Method: Compositional matrix adjust.
 Identities = 46/159 (28%), Positives = 75/159 (47%), Gaps = 14/159 (8%)
 Frame = -2

Query: 60   REARICRLLKHSNIVRLHDSISEEG-------------FHYLVFDLVTGGELFEDIVARE 106
            RE +I + L+H N+V+L +    +              F Y  +DL     L  ++  R 
Sbjct: 1074 REIKILQQLEHENVVQLQEICHTQAGPYNRYKSTFYLIFEYCDYDLAG---LLNNL--RV 910

Query: 107  YYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQG 166
             +S AD  + + Q+L  + + H   ++HRD+K  N+LL    +   +KLADFGL+     
Sbjct: 909  KFSLADKKNLMSQLLNGLFYIHTKQILHRDIKAANILLT---RDGVLKLADFGLSRPWVK 739

Query: 167  DQQAWFGFAGTPGYLSPEVLRKE-AYGKPVDIWACGVIL 204
             ++       T  Y  PE+L  E  YG  +D+W  G I+
Sbjct: 738  SKRL-TNRVVTLWYRPPELLLGEREYGPEIDMWGVGCIM 625
>36002
          Length = 253

 Score = 61.2 bits (147), Expect = 9e-10,   Method: Compositional matrix adjust.
 Identities = 26/55 (47%), Positives = 35/55 (63%)
 Frame = +1

Query: 219 QHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITAHEALKHPWVC 273
           Q  L+ +I+ G Y FPS EW  ++  AK+LI  +L   P KR +A + LKHPWVC
Sbjct: 49  QELLFNRIQDGNYFFPSMEWSAISSSAKDLIRHLLVREPRKRYSAADVLKHPWVC 213
>21418
          Length = 831

 Score = 60.5 bits (145), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 23/57 (40%), Positives = 38/57 (66%)
 Frame = +2

Query: 222 LYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTV 278
           + ++I++G YDFP PEW  V+  AK+LI  ML ++P+KR+   + L++ W+ Q   V
Sbjct: 2   MKKRIRSGQYDFPDPEWTNVSQAAKDLIKGMLNVDPSKRLCIEDVLRNKWIAQYDAV 172
>20152
          Length = 445

 Score = 60.1 bits (144), Expect = 2e-09,   Method: Composition-based stats.
 Identities = 31/91 (34%), Positives = 49/91 (53%), Gaps = 1/91 (1%)
 Frame = +1

Query: 183 PEVLRKEAYGKP-VDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTV 241
           PE+L  ++Y  P VD+W+ GVILY+L+VG  PF + +  +    I    Y  P      +
Sbjct: 1   PEILLGDSYDAPAVDVWSLGVILYMLVVGEAPFQEANDSETLTMIMDCRYQIPP----HI 168

Query: 242 TPEAKNLINQMLTINPAKRITAHEALKHPWV 272
           + + ++LI +ML   P  R +    L HPW+
Sbjct: 169 SHKCQDLIEKMLQREPVDRASLPHILAHPWL 261
>01756
          Length = 1858

 Score = 58.5 bits (140), Expect = 6e-09,   Method: Compositional matrix adjust.
 Identities = 61/220 (27%), Positives = 95/220 (43%), Gaps = 25/220 (11%)
 Frame = -3

Query: 10   FTDEYHLYED---IGKGAFSVV--RRCVKLCTGHEYASKIINTKKLSARDHHK-----LE 59
            F DE   YE    IG+G F  V   RC K         +++  KK+   +  +       
Sbjct: 1757 FCDEDAKYEKLAKIGQGTFGEVFKARCKK-------TKQVVAMKKVLMDNEKEGFPITAL 1599

Query: 60   REARICRLLKHSNIVRLHDSISEEG--------FHYLVFDLV---TGGELFEDIVAREYY 108
            RE +I +LL H N+V L +  S +           YLVF+       G L    V    +
Sbjct: 1598 REIKILQLLNHENVVDLIEICSTKATSANRYKSMFYLVFEFCEHDLAGLLSNMSVV---F 1428

Query: 109  SEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGL--AIEVQG 166
            +  +    ++Q++  + + H+  ++HRD+K  N+L+    K   +KLADFGL  A  V  
Sbjct: 1427 NLPEIKEVMKQLMNGLYYIHRNKILHRDMKAANILIT---KQGVLKLADFGLARAFSVNL 1257

Query: 167  DQ-QAWFGFAGTPGYLSPEVLRKEA-YGKPVDIWACGVIL 204
             Q   +     T  Y  PE+L  +  Y   +D W  G I+
Sbjct: 1256 RQPNRYTNRVVTLWYRPPELLLGDRNYSTAIDQWGAGCIM 1137
>21808
          Length = 1011

 Score = 58.5 bits (140), Expect = 6e-09,   Method: Compositional matrix adjust.
 Identities = 48/195 (24%), Positives = 90/195 (46%), Gaps = 3/195 (1%)
 Frame = +1

Query: 45  INTKKLSARDHHKLEREARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVA 104
           I T K    D      EA+I + L+H  +++L+   +++   +++ +L+  G L E +  
Sbjct: 34  IKTLKSGTMDPKDFLAEAQIMKKLRHPKLIQLYAVCTQDDPIFIITELMKNGSLLEFLQG 213

Query: 105 REYYSEADASHCI-QQILEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIE 163
           +    +  A   I  QI   + +      +HRDL   N+L++       VK+ADFGLA  
Sbjct: 214 KGRVLKLPALIDIGAQIACGMAYLESQNYIHRDLAARNILVSDN---NTVKIADFGLARV 384

Query: 164 VQGDQ-QAWFGFAGTPGYLSPEVLRKEAYGKPVDIWACGVILY-ILLVGYPPFWDEDQHK 221
           ++ D+ +A  G      + +PE      +    D+W+ G++L   +  G  P+      +
Sbjct: 385 IKEDEYEARVGARFPIKWTAPEAANYNRFTIKSDVWSFGILLTETVTYGRVPYPGMTNAE 564

Query: 222 LYQQIKAGAYDFPSP 236
           +  Q++ G Y  P P
Sbjct: 565 VLHQVEHG-YRMPCP 606
>31120
          Length = 439

 Score = 54.7 bits (130), Expect = 8e-08,   Method: Composition-based stats.
 Identities = 28/80 (35%), Positives = 44/80 (55%)
 Frame = +1

Query: 193 KPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQM 252
           K  D W+ GVIL+I+L G  PF D + +KL +  ++  Y F     D V+P A++ ++ +
Sbjct: 31  KMADAWSLGVILFIMLNGKMPFDDSNLNKLLEDQRSKKYSFRRKLQDLVSPNARSTVSVL 210

Query: 253 LTINPAKRITAHEALKHPWV 272
           L  N A R   +E L   W+
Sbjct: 211 LEPNSAMRWDLNEVLNCQWL 270
>20655
          Length = 1181

 Score = 52.8 bits (125), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 21/57 (36%), Positives = 34/57 (59%)
 Frame = +2

Query: 222 LYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTV 278
           + ++I+ G Y+FP PEW  V+ +AK+LI  ML  +P KR+   + +   WV   + V
Sbjct: 2   MKKRIRNGQYEFPKPEWSRVSQDAKDLIRGMLCTDPDKRLNIKQVMASKWVADNTMV 172
>02638
          Length = 1490

 Score = 52.4 bits (124), Expect = 5e-07,   Method: Compositional matrix adjust.
 Identities = 28/96 (29%), Positives = 51/96 (53%), Gaps = 1/96 (1%)
 Frame = +1

Query: 176 GTPGYLSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDED-QHKLYQQIKAGAYDFP 234
           GT  +++PEVLR E+YG+  D+W+ G ++  +    PP+   D  + L    K  +   P
Sbjct: 22  GTIAFMAPEVLRGESYGRACDVWSVGCVMIEMCTCRPPWNSHDISNHLALIFKIASSVDP 201

Query: 235 SPEWDTVTPEAKNLINQMLTINPAKRITAHEALKHP 270
            P  + ++P  ++L+ + L  +   R +A + L HP
Sbjct: 202 PPIPENMSPPVRDLMLRCLEQDSDFRPSAKDLLMHP 309
>17300
          Length = 480

 Score = 52.4 bits (124), Expect = 5e-07,   Method: Composition-based stats.
 Identities = 32/112 (28%), Positives = 55/112 (49%), Gaps = 7/112 (6%)
 Frame = +1

Query: 130 MGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPG------YLSP 183
           MG VHRDL   N+L+         K+ADFGL+ E++ D     G   T G      + +P
Sbjct: 31  MGYVHRDLAARNILVNEIL---VCKVADFGLSREIESDTTE--GAYTTKGGKIPVRWTAP 195

Query: 184 EVLRKEAYGKPVDIWACGVILY-ILLVGYPPFWDEDQHKLYQQIKAGAYDFP 234
           E +    +    D+W+ GV+++ ++  G  P+W+     + + ++ G Y  P
Sbjct: 196 EAIAYRKFTSASDVWSFGVVMWEVMSYGERPYWNWSNQDVIKAVEKG-YRLP 348
>11185
          Length = 473

 Score = 51.6 bits (122), Expect = 7e-07,   Method: Composition-based stats.
 Identities = 40/175 (22%), Positives = 75/175 (42%), Gaps = 22/175 (12%)
 Frame = +1

Query: 119 QILEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLA-IEVQGDQQAWFGFA-- 175
            ++  + + H +G++  DL+P  +LL +      +K ADFGL+ +E +  ++ +F FA  
Sbjct: 25  HLVTGLHYIHSLGILFHDLRPSKVLLDTS---GVLKFADFGLSKVEGENLEELFFKFAEA 195

Query: 176 -------------------GTPGYLSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWD 216
                              G+P Y++PEV +        D+WA G + Y +  G      
Sbjct: 196 GDQWNIQSAEEMMKQVPTSGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFSG------ 357

Query: 217 EDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITAHEALKHPW 271
                   ++ A     PSPE+        NL+  +L  +  +R++    +KH +
Sbjct: 358 -------SRLSAK----PSPEF-------LNLLESLLQKDSTRRLSWASLVKHAF 468
>32000
          Length = 644

 Score = 51.6 bits (122), Expect = 7e-07,   Method: Compositional matrix adjust.
 Identities = 44/146 (30%), Positives = 69/146 (47%), Gaps = 25/146 (17%)
 Frame = -1

Query: 151 AAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRK-EAYGKPVDIWACGVILYILLV 209
           A +K+ADFGLA       + +     T  Y +PE+L     Y  PVDIW+ G I   ++ 
Sbjct: 578 AKMKIADFGLARVFGLPVRTYTHEVITLWYRAPEILLGCRFYSVPVDIWSLGCIFVEMMT 399

Query: 210 GYPPF-WDEDQHKLY----------QQIKAGAYDFPS-----PEW-----DTVTPEAK-- 246
               F  D +  +LY          +++  G    P      P+W     +TV   +K  
Sbjct: 398 RRALFPGDSEIDQLYRIFRTLGTPDEKVWPGVSKLPDYKPTFPKWPLKNLETVVSLSKVG 219

Query: 247 -NLINQMLTINPAKRITAHEALKHPW 271
            +L+ +MLT NP +RI+A  A++HP+
Sbjct: 218 LDLLKRMLTYNPNRRISARSAMRHPY 141
>19094
          Length = 898

 Score = 51.6 bits (122), Expect = 8e-07,   Method: Compositional matrix adjust.
 Identities = 28/93 (30%), Positives = 50/93 (53%)
 Frame = +1

Query: 110 EADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQ 169
           E + +  +   L+ + + H    +HRD+K  N+LL ++      KLADFG+A ++     
Sbjct: 55  EREIATILYYTLKGL*YLHSRRKIHRDIKAGNILLNNE---GHAKLADFGVAGQLTDTMA 225

Query: 170 AWFGFAGTPGYLSPEVLRKEAYGKPVDIWACGV 202
                 GTP +++PEV+++  Y    DIW+ G+
Sbjct: 226 KRNTVIGTPYWMAPEVIQEIGYDCVADIWSLGI 324
>04852
          Length = 1462

 Score = 50.8 bits (120), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 50/219 (22%), Positives = 91/219 (41%), Gaps = 31/219 (14%)
 Frame = +1

Query: 50  LSARDHHKLEREARICRLLK----HSNIVRLHDSISEEGFHYLVFDLVTGGEL------- 98
           ++A +     +E ++ + +K    H NIV      ++ G  +++ +    G L       
Sbjct: 55  VTAVEEQDFVQELQVMKAVKKMGSHINIVNFLGCCTQGGPLWVIVEFAKNGNLRDFLESC 234

Query: 99  ------FEDIVARE---YYSEADASHCIQ---------QILEAVLHCHQMGVVHRDLKPE 140
                 +   V+ +   +Y++    H I+         QI   +        +HRDL   
Sbjct: 235 RDGINGYGKFVSPQDPGWYTKTPGGHVIRRKNLLSYAFQIARGMEFLASRKCIHRDLAAR 414

Query: 141 NLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTP-GYLSPEVLRKEAYGKPVDIWA 199
           N+L+  +     +K+ADFGL+    GD          P  +++PE L    Y    D+W+
Sbjct: 415 NVLVTEE---HVLKIADFGLS--RTGDYYKKRSGGRLPVKWMAPEALFDMRYTTKSDVWS 579

Query: 200 CGVILY-ILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPE 237
            GV+L+ I  +G  P+      +LY ++   AY  P PE
Sbjct: 580 FGVVLWEIFSLGGMPYASIPNEELYSKLLDDAYRMPRPE 696
>03508
          Length = 1463

 Score = 50.1 bits (118), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 26/98 (26%), Positives = 54/98 (55%), Gaps = 1/98 (1%)
 Frame = +1

Query: 108 YSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGD 167
           +++ D    + ++++A+  CH MG++HRD+KP N+++  + K   ++L D+GLA E    
Sbjct: 862 FTDYDIRFYLYELMKALDFCHSMGIMHRDVKPHNVMIDHENK--KLRLIDWGLA-EFYHP 1032

Query: 168 QQAWFGFAGTPGYLSPEVLRK-EAYGKPVDIWACGVIL 204
              +     +  +  PE+L   + Y   +D+W+ G + 
Sbjct: 1033GMEYNVRVASRYFKGPELLLDYQMYDYSLDMWSLGCMF 1146

 Score = 33.1 bits (74), Expect = 0.30,   Method: Compositional matrix adjust.
 Identities = 11/32 (34%), Positives = 23/32 (71%)
 Frame = +2

Query: 241  VTPEAKNLINQMLTINPAKRITAHEALKHPWV 272
            ++PEA + ++++L  +  +R+TA EA+ HP+ 
Sbjct: 1358 ISPEALDFLDKLLRYDHNERLTAREAMDHPYF 1453
>27546
          Length = 426

 Score = 50.1 bits (118), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 35/103 (33%), Positives = 51/103 (49%), Gaps = 1/103 (0%)
 Frame = -1

Query: 60  REARICRLLKHSNIVRLHDSISEEGFHYLVF-DLVTGGELFEDIVAREYYSEADASHCIQ 118
           RE  I   L H NI+++H SI + G    +F      G++   I       EA       
Sbjct: 333 RELEILTRLDHPNIIQIH-SILQRGPKIFIFMRYAEKGDMLSHIKKTGPIDEAQTKVWFF 157

Query: 119 QILEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLA 161
           Q+ +A+ + H   + HRDLK EN+LL+ +     VK+ADFG A
Sbjct: 156 QMAKALQYLHSHDIAHRDLKCENILLSKRLN---VKIADFGFA 37
>27274
          Length = 396

 Score = 49.7 bits (117), Expect = 3e-06,   Method: Composition-based stats.
 Identities = 26/99 (26%), Positives = 52/99 (52%), Gaps = 8/99 (8%)
 Frame = -1

Query: 184 EVLRKEAYGKPVDIWACGVILYILLVGYPPFWDE--------DQHKLYQQIKAGAYDFPS 235
           E+LR + +G  VD+W+ G++L+ LL G+ PF  E        +   +Y QI  G+     
Sbjct: 375 ELLRGQQHGPTVDMWSLGILLHELLSGHVPFEPERGSRQMARNMMAVYAQIIRGS-SRDV 199

Query: 236 PEWDTVTPEAKNLINQMLTINPAKRITAHEALKHPWVCQ 274
            +   ++    + + +++ +   KR+T+ +A  HPW+ +
Sbjct: 198 CDGLALSTHGADFLRRLVQLEDTKRLTSQQAFSHPWIAR 82
>04138
          Length = 800

 Score = 49.7 bits (117), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 54/187 (28%), Positives = 79/187 (42%), Gaps = 36/187 (19%)
 Frame = +1

Query: 122 EAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGL--AIEVQGDQ-QAWFGFAGTP 178
           E + + H+  ++HRD+K  N+L+    K   +KLADFGL  A  V   Q   +     T 
Sbjct: 46  ERLYYIHRNKILHRDMKAANILI---TKQGVLKLADFGLARAFSVNLRQPNRYTNRVVTL 216

Query: 179 GYLSPEVLRKEA-YGKPVDIWACGVI---------------------LYILLVG--YPPF 214
            Y  PE+L  +  Y   +D W  G I                     L   L G   P  
Sbjct: 217 WYRPPELLLGDRNYSTAIDQWGAGCIMAEMWTRNPIMQGTTEQNQLTLITQLCGSITPEV 396

Query: 215 W-DEDQHKLYQQIK----AGAYDFPSPEWDTVT--PEAKNLINQMLTINPAKRITAHEAL 267
           W    Q  +Y QIK    AG  +     +  +   P   +L  ++L ++P++RI+A EAL
Sbjct: 397 WPGVTQLSMYHQIKGALAAGRKNIIRDRFARILKDPYGLDLFERLLKMDPSQRISADEAL 576

Query: 268 KHP--WV 272
            H   WV
Sbjct: 577 NHDFFWV 597
>00715
          Length = 1788

 Score = 49.3 bits (116), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 48/198 (24%), Positives = 82/198 (41%), Gaps = 29/198 (14%)
 Frame = +1

Query: 68  LKHSNIVRLHDSISEEGFH---YLVFDLVTGGELFEDIVAREYYSEADASHCIQ---QIL 121
           L+H N+V +  + S   F    +L  + V  G L    +  ++  + D+S  +    Q+ 
Sbjct: 97  LRHVNVVSILGATSLHRFEDGAWLAMEYV--GPLNLQTILNDHQQDIDSSMRLSLALQMA 270

Query: 122 EAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLA-------------------- 161
             + + H + +VH DLKP N LL    K   +++ADFG                      
Sbjct: 271 RGLHYLHSINIVHLDLKPANCLLTRDLK---LRIADFGCCHQLTPTGLDMGEREGGMAGN 441

Query: 162 -IEVQGDQQAWFG-FAGTPGYLSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQ 219
            +E+   Q AW    AGT  Y +PE+L+        D+++ G+ L+ +     P+     
Sbjct: 442 ELELTPVQGAWKNELAGTLAYRAPELLKGLQPSVRSDVYSLGITLWQMCTRQGPYEGVPA 621

Query: 220 HK-LYQQIKAGAYDFPSP 236
           H  +YQ +       P P
Sbjct: 622 HAVVYQVVSKDLRPCPPP 675
>17722
          Length = 680

 Score = 48.1 bits (113), Expect = 8e-06,   Method: Compositional matrix adjust.
 Identities = 24/72 (33%), Positives = 39/72 (54%)
 Frame = -3

Query: 195 VDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLT 254
           VD W  GV++Y ++ G  PF++ D   L++ I      FP      ++ EAK L++ +L 
Sbjct: 678 VDWWGTGVVMYEMMCGRLPFYNRDHDVLFELILLQNVKFPR----NLSEEAKTLLSGLLA 511

Query: 255 INPAKRITAHEA 266
            NP +R+   EA
Sbjct: 510 KNPKRRLGGSEA 475
>14116
          Length = 1017

 Score = 47.8 bits (112), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 52/205 (25%), Positives = 90/205 (43%), Gaps = 14/205 (6%)
 Frame = -1

Query: 18  EDIGKGAFSVVRRCVKLCTGHEYASKIINTKKLSARDHHKLE-----REARICRLLKHSN 72
           E+IGKG F  V+R   L    +    ++  K L   +  ++E     +EA I +   HSN
Sbjct: 618 EEIGKGNFGCVKRGF-LTLPEQKGDILVAVKTLHNNNPREIELQSFLQEALIMKDFHHSN 442

Query: 73  IVRLHD-SISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQ---QILEAVLHCH 128
           ++ L    ++ +    +V   +  G+L   I  R+   +      I     I   + +  
Sbjct: 441 VLTLIGICLNLDDMPLVVLPFMKHGDLLTYI--RDDQHQPTIKDLIMYGVDIARGMDYLA 268

Query: 129 QMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPG-----YLSP 183
            +  VHRDL   N +L        VK+ADFGLA ++   ++ ++            +++ 
Sbjct: 267 GLKFVHRDLAARNCMLDEDFH---VKVADFGLARDIY--EKEYYSSENKKAKLPVKWMAL 103

Query: 184 EVLRKEAYGKPVDIWACGVILYILL 208
           E L K  Y    D+W+ GV+L+ LL
Sbjct: 102 ESLEKGNYDSKTDVWSYGVVLWELL 28
>31489
          Length = 329

 Score = 46.2 bits (108), Expect = 3e-05,   Method: Composition-based stats.
 Identities = 28/87 (32%), Positives = 48/87 (55%), Gaps = 6/87 (6%)
 Frame = +3

Query: 63  RICRLLKHSNIVRLHDSIS-EEGFH-----YLVFDLVTGGELFEDIVAREYYSEADASHC 116
           +I +  KH NI+ + + +  ++ +H     ++VFDL+   +L   I + +  +E    + 
Sbjct: 6   KILKHFKHDNIISIREILKPKDSYHDFKDIHVVFDLMES-DLHRIIYSDQPLTEEHIRYF 182

Query: 117 IQQILEAVLHCHQMGVVHRDLKPENLL 143
           + QIL  + + H   VVHRDLKP NLL
Sbjct: 183 LYQILRGLKYIHSANVVHRDLKPSNLL 263
>28157
          Length = 400

 Score = 46.2 bits (108), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 33/104 (31%), Positives = 53/104 (50%), Gaps = 6/104 (5%)
 Frame = +3

Query: 68  LKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVL-- 125
           + H NIV L+ +  +     LV +   GG L+  +       +  A+H +  +L+  L  
Sbjct: 81  VSHPNIVCLYGACRDHPV-CLVMEYAEGGSLYNVLHGSGPQPQYTAAHAMNWLLQCALGV 257

Query: 126 -HCHQM---GVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQ 165
            + H M    ++HRDLKP NLLL  +C G  +K+ DFG A ++ 
Sbjct: 258 EYLHGMKPKALIHRDLKPPNLLLI-QC-GTKLKICDFGTACDIH 383
>07291
          Length = 833

 Score = 45.8 bits (107), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 29/118 (24%), Positives = 60/118 (50%), Gaps = 6/118 (5%)
 Frame = +1

Query: 118 QQILEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGT 177
           +QI + + +  ++ VVHR+L   N ++    +   ++L+D+G+   +    Q+++    +
Sbjct: 70  RQIADGMAYLQEVKVVHRNLAARNCIVTEDGR---LQLSDYGVTGSLF--PQSYYTADDS 234

Query: 178 PG-----YLSPEVLRKEAYGKPVDIWACGVILYILLV-GYPPFWDEDQHKLYQQIKAG 229
           P      +++PE +    +    D+WA GV+L+ LL  G  P+ D +   L   +K G
Sbjct: 235 PARDLVKWMAPETIDNFHFSSKSDVWAFGVVLWELLTRGITPYPDVENSSLLPYLKEG 408
>11780
          Length = 1713

 Score = 45.8 bits (107), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 42/148 (28%), Positives = 68/148 (45%), Gaps = 4/148 (2%)
 Frame = +3

Query: 18  EDIGKGAFSVVRRCVKLCTGHEYASKIINTKKLSARDH--HKLEREARICRLLKHSNIVR 75
           E IGKG F  V + +       Y  + +  K+L  +D       +EA +   L+H N+VR
Sbjct: 615 EAIGKGDFGDVYKGM-------YRGQPVAIKQLKDKDRGEQSFLQEASVMTSLRHDNLVR 773

Query: 76  LHDSISEEGFHYLVFDLVTGGELFEDIVA--REYYSEADASHCIQQILEAVLHCHQMGVV 133
           L   +  E   +LV + +  G L E + +  R   ++ D  +       A+ +     +V
Sbjct: 774 LIGVVLGETI-FLVTEFMGKGNLVEYLRSRGRSVITKKDQINFATDTCAAMEYLESKRLV 950

Query: 134 HRDLKPENLLLASKCKGAAVKLADFGLA 161
           HRDL   N+L+    K    K++DFGLA
Sbjct: 951 HRDLAARNVLVHDDGK---AKVSDFGLA 1025
>19301
          Length = 712

 Score = 45.4 bits (106), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 28/101 (27%), Positives = 49/101 (48%)
 Frame = +2

Query: 59  EREARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQ 118
           E + R  R L H NI+      ++   + ++ +    G+L+E +   +    A      +
Sbjct: 413 ETDIRNLRKLNHPNIISFKGVCTQAPCYCIIMEYCPYGQLYEVLRDGKEIPPALVLDWSK 592

Query: 119 QILEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFG 159
           QI   + + H   ++HRDLK  N+L+A   K   VK++DFG
Sbjct: 593 QIASGMNYLHSHKIIHRDLKSPNVLVA---KNDVVKISDFG 706
>25019
          Length = 730

 Score = 45.4 bits (106), Expect = 6e-05,   Method: Compositional matrix adjust.
 Identities = 26/62 (41%), Positives = 34/62 (54%)
 Frame = +3

Query: 140 ENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKEAYGKPVDIWA 199
           EN+LL    K   VKL DFGL  E     +    F GT  Y++PE+L +  +GK VD W+
Sbjct: 261 ENVLLD---KDGHVKLTDFGLCKEAITGTRVTHTFCGTIEYMAPEILTRTGHGKAVDWWS 431

Query: 200 CG 201
            G
Sbjct: 432 LG 437
>11404
          Length = 563

 Score = 43.9 bits (102), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 42/155 (27%), Positives = 68/155 (43%), Gaps = 17/155 (10%)
 Frame = +1

Query: 9   RFTDEYHLYEDIGKGAFSVVRRCVKLCTGHEYASKIINTKK------------LSARDHH 56
           ++ D Y +   IGKG+F  V +        + A KII  KK            L   + H
Sbjct: 130 KWADRYEIDSLIGKGSFGQVVKAYDHTDNEQVAIKIIKNKKPFLNQAQIEVKLLEMMNRH 309

Query: 57  KLEREARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDI---VAREYYSEADA 113
             + +  I RL +H  + R H  +  E   Y ++DL+     F  +   + R++      
Sbjct: 310 DTDNKYYIVRLKRHF-MFRSHLCLVFELLSYNLYDLLRNTN-FRGVSLNLTRKF------ 465

Query: 114 SHCIQQILEAVLHCH--QMGVVHRDLKPENLLLAS 146
               QQ+  A+L     +M ++H DLKPEN+LL +
Sbjct: 466 ---AQQLCTALLFLATPEMSIIHCDLKPENILLCN 561
>29590
          Length = 320

 Score = 42.7 bits (99), Expect = 4e-04,   Method: Composition-based stats.
 Identities = 17/39 (43%), Positives = 24/39 (61%)
 Frame = +3

Query: 176 GTPGYLSPEVLRKEAYGKPVDIWACGVILYILLVGYPPF 214
           GTP Y++PEVL  E      D+W+ GV+ Y++L    PF
Sbjct: 60  GTPDYVAPEVLDYEPLSIQTDMWSLGVLSYVMLTACSPF 176
>07940
          Length = 1336

 Score = 42.7 bits (99), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 30/102 (29%), Positives = 50/102 (49%), Gaps = 6/102 (5%)
 Frame = -3

Query: 119 QILEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTP 178
           Q+   + +      +HRDL   N+L+A +     +K+ADFGL   +Q   Q  +    T 
Sbjct: 323 QVARGMEYLASKQCIHRDLAARNVLVAEEY---VLKIADFGLTRNLQ---QFDYYRKTTD 162

Query: 179 G-----YLSPEVLRKEAYGKPVDIWACGVILY-ILLVGYPPF 214
           G     +++PE L    Y    D+W+ GV+L+ I  +G  P+
Sbjct: 161 GRLPVKWMAPEALFDRKYTSKSDVWSYGVLLWEIFTLGGNPY 36
>32957
          Length = 645

 Score = 42.0 bits (97), Expect = 6e-04,   Method: Compositional matrix adjust.
 Identities = 21/51 (41%), Positives = 30/51 (58%)
 Frame = +3

Query: 158 FGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKEAYGKPVDIWACGVILYILL 208
           F L +E  G +     F GT  Y++PEV  ++ YGK VD W  G++L+ LL
Sbjct: 3   FALCVEKSGGRTR--TFCGTREYMAPEVHERKEYGKEVDWWGLGILLHELL 149
>18996
          Length = 491

 Score = 41.2 bits (95), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 31/113 (27%), Positives = 51/113 (45%), Gaps = 8/113 (7%)
 Frame = +2

Query: 133 VHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTP---GYLSPEVLRKE 189
           +HRDL   N+L+   C    VK++DFGLA     D   ++G +       + SPE +   
Sbjct: 2   IHRDLAARNILVDRSC----VKISDFGLAQFANADG-YYYGISQRDIPIKWYSPEAIETC 166

Query: 190 AYGKPVDIWACGVILYIL-----LVGYPPFWDEDQHKLYQQIKAGAYDFPSPE 237
            +    D+W+ GV L+ +     +    P  D  Q +   +++ G    P PE
Sbjct: 167 KFSSYSDVWSYGVTLFEMFSRGEIPNLLPGHDLTQEEFLNRLRKGE-RLPKPE 322
>18481
          Length = 437

 Score = 41.2 bits (95), Expect = 0.001,   Method: Composition-based stats.
 Identities = 33/125 (26%), Positives = 60/125 (48%), Gaps = 5/125 (4%)
 Frame = -1

Query: 49  KLSARD--HHKLEREARICRLL-KHSNIVRLHDSISEEGFHYLVFDLVTGG--ELFEDIV 103
           K+ A D  H  L  EA++   + +H  +  ++   +E+ F+ LV +L+     ELF  ++
Sbjct: 392 KIEAIDVKHQLLHYEAKVYEQIGRHPGLPTMYHYGTEKHFNALVMELLGPSLEELF--VI 219

Query: 104 AREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIE 163
            +  ++         Q+L  +   HQ   +HRDLKP+N L+        + + DFGL+  
Sbjct: 218 CKRRFTLKTILMVSDQLLSRLEFIHQKCFIHRDLKPDNFLMGLGRHCHRLYIIDFGLSKR 39

Query: 164 VQGDQ 168
            +  Q
Sbjct: 38  YKDTQ 24
>01106
          Length = 878

 Score = 41.2 bits (95), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 39/153 (25%), Positives = 69/153 (45%), Gaps = 18/153 (11%)
 Frame = +3

Query: 10  FTDEYHLYEDIGKGAFSVVRRCVKLCTGHEYASKIINTKKLSARDHHKLER---EARICR 66
           F   YH+   +G G FS V  C  L      A K++ + +      H  E    E ++ +
Sbjct: 312 FNGRYHVIRKLGWGHFSTVWLCWDLTCKRFVALKVVKSAQ------HYTETALDEVKLLK 473

Query: 67  LLKHSNI--------VRLHDSISEEGFH----YLVFDLVTGGELFEDIVAREYYSEA--D 112
            ++ S++        V+L D     G +     +VF+ V G  L + I+   Y      +
Sbjct: 474 CVRESDVADPARAKCVQLLDDFKISGVNGTHVAMVFE-VLGYNLLKLIIRSNYQGIPIHN 650

Query: 113 ASHCIQQILEAVLHCH-QMGVVHRDLKPENLLL 144
               I+Q+LE + + H +  ++H D+KPEN+L+
Sbjct: 651 VKLIIRQVLEGLSYMHAKCRIIHTDIKPENILI 749
>20773
          Length = 391

 Score = 40.0 bits (92), Expect = 0.002,   Method: Composition-based stats.
 Identities = 17/39 (43%), Positives = 25/39 (64%)
 Frame = -1

Query: 236 PEWDTVTPEAKNLINQMLTINPAKRITAHEALKHPWVCQ 274
           P    VT    NL+ ++LT +P++R+T   AL HP+VCQ
Sbjct: 337 PHTTVVTQHFYNLVQRLLTYDPSQRLTPDLALSHPFVCQ 221
>37063
          Length = 455

 Score = 38.9 bits (89), Expect = 0.006,   Method: Composition-based stats.
 Identities = 27/83 (32%), Positives = 42/83 (50%), Gaps = 10/83 (12%)
 Frame = -2

Query: 137 LKPENLLLASKCKGAAVKLADFGLA--IEVQGD---QQAWFGFAGTPGYLSPEVL----- 186
           LKPEN+L     +   +K+ DF LA  I   GD           G+  Y++PEV+     
Sbjct: 454 LKPENILCEHLDEVVPLKICDFDLASGINCDGDGTKTPELLTPVGSAEYMAPEVVDAWVG 275

Query: 187 RKEAYGKPVDIWACGVILYILLV 209
              +Y K  D+W+ G+IL +L++
Sbjct: 274 ESFSYDKRCDMWSLGIIL*VLVM 206
>36481
          Length = 806

 Score = 38.5 bits (88), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 43/151 (28%), Positives = 65/151 (43%), Gaps = 9/151 (5%)
 Frame = +2

Query: 4   TVTCTRFTDEYHLYEDIGKGAFSVVRRCVKLCTGHEYASKII-NTKKLSARDHHKLEREA 62
           T+  T  T++  L    G+G F  V +C  L  G + A KII N  K   R+  KLE   
Sbjct: 338 TMRGTSSTNDMKLCPHWGEGTFGKVVQCKDLLKGDDIALKIIKNVDKY--REAAKLE--I 505

Query: 63  RICRLLKHSN------IVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREY--YSEADAS 114
            +   L+  +       V++ D     G   + F ++ G  +F+ +    Y  Y      
Sbjct: 506 NVLEKLREKDPHAKHMCVQMLDWFDYHGHVCISFHML-GLSVFDFLKDNSYGAYPIEQVR 682

Query: 115 HCIQQILEAVLHCHQMGVVHRDLKPENLLLA 145
           H   Q+  AV   H+  + H DLKPEN+L  
Sbjct: 683 HISYQLCYAVNFLHENQLTHTDLKPENILFV 775
>17644
          Length = 463

 Score = 37.7 bits (86), Expect = 0.011,   Method: Compositional matrix adjust.
 Identities = 16/39 (41%), Positives = 24/39 (61%)
 Frame = +3

Query: 236 PEWDTVTPEAKNLINQMLTINPAKRITAHEALKHPWVCQ 274
           P    VT    +L+ ++LT +P++R+T   AL HP+VCQ
Sbjct: 54  PHTTVVTQHFYBLVQRLLTYDPSQRLTPDLALSHPFVCQ 170
>12672
          Length = 773

 Score = 37.7 bits (86), Expect = 0.011,   Method: Compositional matrix adjust.
 Identities = 26/92 (28%), Positives = 44/92 (47%), Gaps = 4/92 (4%)
 Frame = +3

Query: 123 AVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQ----QAWFGFAGTP 178
            + + +  G VHRD+K  N+LL S+      K+ DF   +     +    Q      GT 
Sbjct: 27  GIQYLNDNGHVHRDIKTANILLDSEYTA---KVGDFATVVSAPSGEGKTVQNASVVIGTA 197

Query: 179 GYLSPEVLRKEAYGKPVDIWACGVILYILLVG 210
            YL+PE +  +   K +D ++ GV+L  ++ G
Sbjct: 198 AYLAPEAIHFDVSTK-LDSYSFGVVLLEVITG 290
>18401
          Length = 463

 Score = 37.4 bits (85), Expect = 0.015,   Method: Compositional matrix adjust.
 Identities = 15/44 (34%), Positives = 23/44 (52%)
 Frame = -3

Query: 175 AGTPGYLSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDED 218
             T  Y +PEV+ +  +  P D+W+ G I++ L  GY  F   D
Sbjct: 449 VSTRHYRAPEVILELGWSHPCDVWSVGCIMFELYTGYTLFQTHD 318
>00394
          Length = 548

 Score = 37.4 bits (85), Expect = 0.015,   Method: Compositional matrix adjust.
 Identities = 25/86 (29%), Positives = 41/86 (47%), Gaps = 5/86 (5%)
 Frame = -2

Query: 18  EDIGKGAFSVVRRCVKLCTGHEYASKIINTKKLSARDHHKLEREARICRLLKHSNIVRLH 77
           ++IG+G+F  V + +    G   A   +  KK +  +  + + EA + + L+H NIVR  
Sbjct: 280 KEIGRGSFKTVYKGLDTELGVAVAWCELQDKKWNKAERQRFKEEAEMLKELQHPNIVRFF 101

Query: 78  DSISEEGFH-----YLVFDLVTGGEL 98
           D   E          LV +L+T G L
Sbjct: 100 DYWEEHNHRNRKVIILVTELMTSGTL 23
>18287
          Length = 678

 Score = 37.0 bits (84), Expect = 0.019,   Method: Compositional matrix adjust.
 Identities = 16/31 (51%), Positives = 22/31 (70%)
 Frame = -3

Query: 242 TPEAKNLINQMLTINPAKRITAHEALKHPWV 272
           T EA  L+ +ML +NP  RI+A EAL HP++
Sbjct: 436 THEAVRLLTRMLILNPKNRISAEEALSHPYL 344
>31789
          Length = 676

 Score = 37.0 bits (84), Expect = 0.020,   Method: Compositional matrix adjust.
 Identities = 25/85 (29%), Positives = 40/85 (47%), Gaps = 5/85 (5%)
 Frame = +2

Query: 19  DIGKGAFSVVRRCVKLCTGHEYASKIINTKKLSARDHHKLEREARICRLLKHSNIVRLHD 78
           +IG+G+F  V + +    G   A   +  KK +  +  + + EA + + L+H NIVR  D
Sbjct: 341 EIGRGSFKTVYKGLDTELGVAVAWCELQDKKWNKTERQRFKEEAEMLKELQHPNIVRFFD 520

Query: 79  SISEEGFH-----YLVFDLVTGGEL 98
              E          LV +L+T G L
Sbjct: 521 YWEEHNHRNRKVIILVTELMTSGTL 595
>29360
          Length = 363

 Score = 36.2 bits (82), Expect = 0.030,   Method: Compositional matrix adjust.
 Identities = 21/77 (27%), Positives = 37/77 (48%), Gaps = 3/77 (3%)
 Frame = +3

Query: 72  NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHC---IQQILEAVLHCH 128
           N VR  +    +    LVF+++       D + +  +      +     QQ+L A+    
Sbjct: 138 NFVRAFECFQHKNHTCLVFEMLEQN--LYDFLKQNKFQPLPLKYIRPITQQVLTALRKLK 311

Query: 129 QMGVVHRDLKPENLLLA 145
           Q+G++H DLKPEN++L 
Sbjct: 312 QLGLIHADLKPENIMLV 362
>23319
          Length = 2235

 Score = 36.2 bits (82), Expect = 0.038,   Method: Compositional matrix adjust.
 Identities = 29/115 (25%), Positives = 51/115 (44%), Gaps = 26/115 (22%)
 Frame = +3

Query: 183 PEVLRKEAYGKPVDIWACGVILYILLVGYPPFW----DEDQHK-LYQQIKAGAYD----- 232
           P+V   + Y   +D+W+ G I   L     P +    D+DQ K +++ +     D     
Sbjct: 3   PDVYXAKMYSTSIDMWSAGCIFAELANAGRPLFPGNDDDDQLKRIFKLLGTPTEDQWPGM 182

Query: 233 --------FP----SPEWDTVTPE----AKNLINQMLTINPAKRITAHEALKHPW 271
                   FP    +  W  V P+     ++L+  +L   P+ R++A EAL+HP+
Sbjct: 183 TQLPNYRMFPMYHVTTTWQQVVPKLNSKGRDLLQCLLVCCPSDRMSADEALQHPY 347
>00638
          Length = 1595

 Score = 35.8 bits (81), Expect = 0.048,   Method: Compositional matrix adjust.
 Identities = 11/32 (34%), Positives = 23/32 (71%)
 Frame = +2

Query: 108 YSEADASHCIQQILEAVLHCHQMGVVHRDLKP 139
           +++ D    + ++++A+  CH MG++HRD+KP
Sbjct: 407 FTDYDIRFYLYELMKALDFCHSMGIMHRDVKP 502
>16708
          Length = 1397

 Score = 35.0 bits (79), Expect = 0.081,   Method: Compositional matrix adjust.
 Identities = 19/47 (40%), Positives = 30/47 (63%), Gaps = 1/47 (2%)
 Frame = -1

Query: 116  CIQ-QILEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLA 161
            CI  Q + A+ H H++GVVH D+K +N+L+ +       KL D+G+A
Sbjct: 1082 CIAGQXVCALEHIHELGVVHMDVKADNVLVDAH---GNCKLTDYGIA 951
>37602
          Length = 804

 Score = 34.3 bits (77), Expect = 0.12,   Method: Compositional matrix adjust.
 Identities = 23/75 (30%), Positives = 36/75 (48%), Gaps = 5/75 (6%)
 Frame = -1

Query: 109 SEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADF-----GLAIE 163
           +E   +   ++ L+ + + H+ G +HRD+K  N+LL  +     VKLADF       +  
Sbjct: 225 TEPQIAFVCRETLKGLHYLHRRGKMHRDIKGANILLTEE---GDVKLADFWRVSSNHSHN 55

Query: 164 VQGDQQAWFGFAGTP 178
           VQ     W  F G P
Sbjct: 54  VQKKVFHWNAFIGWP 10
>14104
          Length = 573

 Score = 33.9 bits (76), Expect = 0.17,   Method: Compositional matrix adjust.
 Identities = 11/36 (30%), Positives = 24/36 (66%)
 Frame = +1

Query: 237 EWDTVTPEAKNLINQMLTINPAKRITAHEALKHPWV 272
           ++    P+A + +   L ++PA+R+T H+ L+HP++
Sbjct: 76  KFSNAAPQAMSFMQSCLKMDPAERLTCHQLLQHPYM 183
>26009
          Length = 886

 Score = 33.1 bits (74), Expect = 0.27,   Method: Compositional matrix adjust.
 Identities = 13/33 (39%), Positives = 23/33 (69%)
 Frame = +3

Query: 112 DASHCIQQILEAVLHCHQMGVVHRDLKPENLLL 144
           +A   ++Q++ A+   H   +VHRD+KPEN+L+
Sbjct: 714 EAKSVMKQLVSALDFMHSKQLVHRDIKPENVLI 812
>17516
          Length = 453

 Score = 33.1 bits (74), Expect = 0.28,   Method: Composition-based stats.
 Identities = 16/38 (42%), Positives = 24/38 (63%), Gaps = 1/38 (2%)
 Frame = -3

Query: 174 FAGTPGYLSPEV-LRKEAYGKPVDIWACGVILYILLVG 210
            AGTP Y++PEV L+K  Y    D+++  +IL+ L  G
Sbjct: 439 LAGTPVYMAPEVLLQKGQYDMKADVYSLAIILWELWYG 326
>03106
          Length = 2384

 Score = 33.1 bits (74), Expect = 0.28,   Method: Compositional matrix adjust.
 Identities = 23/69 (33%), Positives = 32/69 (46%), Gaps = 1/69 (1%)
 Frame = +2

Query: 196 DIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEA-KNLINQMLT 254
           D+WA G + Y +     PF+       Y Q     +D PS   D  TPE    L+  ML 
Sbjct: 32  DVWAAGAVAYEIFGASNPFYSRLDSACYSQ-----HDLPSLPGD--TPEGVVRLVTSMLE 190

Query: 255 INPAKRITA 263
            +PA+R +A
Sbjct: 191 RDPAQRPSA 217
>07836
          Length = 1478

 Score = 33.1 bits (74), Expect = 0.28,   Method: Compositional matrix adjust.
 Identities = 25/86 (29%), Positives = 43/86 (50%), Gaps = 11/86 (12%)
 Frame = -1

Query: 131  GVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQ----AWFGFAGTPGYLSPEVL 186
             + HRD+K +N+L+    K     +AD GLA+    +      A     GT  Y++PEVL
Sbjct: 1172 AIAHRDIKSKNILVK---KNGTCCIADLGLAVRYISESNEVDVAPNPRQGTKRYMAPEVL 1002

Query: 187  RK-------EAYGKPVDIWACGVILY 205
                     +A+ K  D++A G++++
Sbjct: 1001 EMLLNVKNFDAF-KQADMYAFGLVMW 927
>32359
          Length = 928

 Score = 32.7 bits (73), Expect = 0.34,   Method: Compositional matrix adjust.
 Identities = 22/62 (35%), Positives = 32/62 (51%), Gaps = 5/62 (8%)
 Frame = -1

Query: 20  IGKGAFSVVRRCVKLCTGHEYASKIINTKKLSA-----RDHHKLEREARICRLLKHSNIV 74
           IG G+F VV           Y +K+++T +L A     +D     RE +I R L+H NIV
Sbjct: 406 IGNGSFGVV-----------YQAKLVDTSELVAIKKVLQDKRFKNRELQIMRKLEHQNIV 260

Query: 75  RL 76
           +L
Sbjct: 259 KL 254

 Score = 28.1 bits (61), Expect = 9.1,   Method: Compositional matrix adjust.
 Identities = 11/14 (78%), Positives = 13/14 (92%)
 Frame = -3

Query: 131 GVVHRDLKPENLLL 144
           GV HRD+KP+NLLL
Sbjct: 65  GVCHRDIKPQNLLL 24
>20513
          Length = 405

 Score = 32.3 bits (72), Expect = 0.44,   Method: Compositional matrix adjust.
 Identities = 14/37 (37%), Positives = 23/37 (62%), Gaps = 1/37 (2%)
 Frame = -1

Query: 237 EWDTVTPEA-KNLINQMLTINPAKRITAHEALKHPWV 272
           EWD    +A  + +  ML  +P +R TA ++L+HPW+
Sbjct: 315 EWDPKDAKAFADFLAPMLEFDPEQRATAAQSLQHPWL 205
>15549
          Length = 470

 Score = 32.3 bits (72), Expect = 0.44,   Method: Composition-based stats.
 Identities = 15/38 (39%), Positives = 20/38 (52%)
 Frame = -1

Query: 8   TRFTDEYHLYEDIGKGAFSVVRRCVKLCTGHEYASKII 45
           +RF DE+   E +GKG + +V R        EYA K I
Sbjct: 230 SRFADEFECIEQMGKGGYGIVFRAKNKVDEQEYAVKRI 117
>20559
          Length = 430

 Score = 32.3 bits (72), Expect = 0.50,   Method: Composition-based stats.
 Identities = 28/83 (33%), Positives = 39/83 (46%), Gaps = 5/83 (6%)
 Frame = -2

Query: 13  EYHLYEDIGKGAFSVVRRCVKLCTGHEYASKIINTKKLSARDHHK-----LEREARICRL 67
           +Y   E IG+G +  V +     T HE    I+  K++   D  +       RE  + + 
Sbjct: 372 KYEKLEKIGEGTYGTVFKAKNRET-HE----IVALKRVRLDDDDEGVPSSALREICLLKE 208

Query: 68  LKHSNIVRLHDSISEEGFHYLVF 90
           LKH NIVRLHD +  E    LVF
Sbjct: 207 LKHRNIVRLHDVLHSERKLTLVF 139
>16350
          Length = 1108

 Score = 32.3 bits (72), Expect = 0.52,   Method: Compositional matrix adjust.
 Identities = 14/37 (37%), Positives = 23/37 (62%), Gaps = 1/37 (2%)
 Frame = +3

Query: 237 EWDTVTPEA-KNLINQMLTINPAKRITAHEALKHPWV 272
           EWD    +A  + +  ML  +P +R TA ++L+HPW+
Sbjct: 729 EWDPKDAKAFADFLAPMLEFDPEQRATAAQSLQHPWL 839

 Score = 32.3 bits (72), Expect = 0.55,   Method: Compositional matrix adjust.
 Identities = 25/83 (30%), Positives = 32/83 (38%), Gaps = 8/83 (9%)
 Frame = +2

Query: 136 DLKPENLLLASKCKGAAVKLADFGLAI--------EVQGDQQAWFGFAGTPGYLSPEVLR 187
           D KPE   +   C    VK+AD G A         ++Q  Q           Y   EVL 
Sbjct: 305 DNKPECDPVNEICTDFPVKIADLGNACWTYHHFTEDIQTRQ-----------YRCLEVLI 451

Query: 188 KEAYGKPVDIWACGVILYILLVG 210
              YG P DIW+   + + L  G
Sbjct: 452 GAGYGTPADIWSTACMAFELATG 520
>08294
          Length = 1849

 Score = 32.3 bits (72), Expect = 0.54,   Method: Compositional matrix adjust.
 Identities = 38/148 (25%), Positives = 66/148 (44%), Gaps = 5/148 (3%)
 Frame = +2

Query: 118  QQILEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGT 177
            QQ+   +      G+VH DL   N+LL S+ +   +K+A   L+ +V   +         
Sbjct: 1064 QQVAAGMEALSNQGLVHGDLAARNVLLTSRMQ---LKVARPALSGDVYASEYYPLHQRLV 1234

Query: 178  P-GYLSPEVLRKEAYGKPVDIWACGVILYILL----VGYPPFWDEDQHKLYQQIKAGAYD 232
            P  +L PE + +++     D+WA GV L+ +L    + Y    DE+  +  Q  +A A D
Sbjct: 1235 PLRWLPPEGVLEDSATTCGDVWAFGVFLWEVLQLADLPYRLMSDEEVLRSLQHSQA-ALD 1411

Query: 233  FPSPEWDTVTPEAKNLINQMLTINPAKR 260
             P        P   +L+ +     P++R
Sbjct: 1412 SPD-----APPALLSLLQRCTAQQPSQR 1480
>13305
          Length = 549

 Score = 32.0 bits (71), Expect = 0.72,   Method: Compositional matrix adjust.
 Identities = 15/51 (29%), Positives = 27/51 (52%), Gaps = 1/51 (1%)
 Frame = +2

Query: 180 YLSPEVLRKEAYGKPVDIWACGVILY-ILLVGYPPFWDEDQHKLYQQIKAG 229
           +++ E L    Y    D+W+ GV+L+ I  +G  P+   D  +L+  +K G
Sbjct: 23  WMAVESLFNNTYTTQSDVWSFGVVLWEIFTLGGTPYSSTDTQQLFAFLKDG 175
>21800
          Length = 855

 Score = 31.2 bits (69), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 19/65 (29%), Positives = 33/65 (50%), Gaps = 3/65 (4%)
 Frame = +2

Query: 84  GFHYLVFDLVTGGELFEDIVAREYYSEA--DASHCIQQILEAVLHCH-QMGVVHRDLKPE 140
           G H  +   V G  L + I+   Y      +    I+Q+LE + + H +  ++H D+KPE
Sbjct: 545 GTHVCMVFEVLGYNLLKLIIRSNYQGIPVHNVKLIIRQVLEGLNYLHAKCNIIHTDIKPE 724

Query: 141 NLLLA 145
           N+L+ 
Sbjct: 725 NILIC 739
>03294
          Length = 1684

 Score = 30.4 bits (67), Expect = 2.1,   Method: Compositional matrix adjust.
 Identities = 27/109 (24%), Positives = 48/109 (44%), Gaps = 25/109 (22%)
 Frame = -1

Query: 194  PVDIWACGVILYILLVGYPPFWDEDQ----HKLYQQI------------KAGAYDFPSPE 237
            PVD+W+ G I   +L+  P F  + +     K+++ I            K  A++   P 
Sbjct: 1675 PVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIFRIIGTPTEQTWPEFHKLPAFNGMFPL 1496

Query: 238  W------DTVT---PEAKNLINQMLTINPAKRITAHEALKHPWVCQRST 277
            W      +T+T       +LI + L  +PA+RI+  + L+H +     T
Sbjct: 1495 WKEGKLSETLTDLDSLGLDLIERTLKCDPAQRISCKKMLQHAYFLNVDT 1349
>33586
          Length = 551

 Score = 30.0 bits (66), Expect = 2.2,   Method: Compositional matrix adjust.
 Identities = 14/48 (29%), Positives = 25/48 (52%)
 Frame = +2

Query: 73  IVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
           IV LH +   EG  YL+ + + GG+LF  +     ++E D    + ++
Sbjct: 407 IVHLHYAFQTEGKLYLILEFLRGGDLFTRLSKEVMFTEEDVKFYLAEL 550
>31232
          Length = 993

 Score = 29.3 bits (64), Expect = 4.7,   Method: Compositional matrix adjust.
 Identities = 10/26 (38%), Positives = 19/26 (73%)
 Frame = +2

Query: 450 GNLVEGMDFHRFYFENLLAKNSKPIH 475
           G+++  +D +RFYF+N+L K S  ++
Sbjct: 332 GDILNTLDMYRFYFKNILNKMSDKVN 409
>13078
          Length = 773

 Score = 28.1 bits (61), Expect = 9.5,   Method: Compositional matrix adjust.
 Identities = 10/29 (34%), Positives = 16/29 (55%)
 Frame = -1

Query: 190 AYGKPVDIWACGVILYILLVGYPPFWDED 218
            + +P D+W+ G I++ L  GY  F   D
Sbjct: 749 GWSQPCDVWSIGCIMFELYTGYTLFQTHD 663
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|46852153|ref|NP_085036.2| vacuolar protein sorting 16
[Mus musculus]
         (839 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

11075                                                                 186   3e-47
15444                                                                  81   1e-15
30042                                                                  30   3.3  
37432                                                                  26   8.1  
>11075
          Length = 2368

 Score =  186 bits (472), Expect = 3e-47,   Method: Compositional matrix adjust.
 Identities = 95/206 (46%), Positives = 143/206 (69%)
 Frame = +2

Query: 517 VSYSDIAARAYGCGRTELAIKLLEYEPRSGEQVPLLLKMKRSKLALSKAIESGDTDLVFT 576
           V +SDIA++A   GR +LA+KLLE+EPR+ EQVPLLLKM +   AL+KAI+SGDTDLV+T
Sbjct: 2   VLFSDIASQALEHGRKQLAVKLLEFEPRASEQVPLLLKMGQLGPALNKAIDSGDTDLVYT 181

Query: 577 VLLHLKNELNRGDFFMTLRNQPMALSLYRQFCKHQELDTLKDLYNQDDNHQELGSFHIRA 636
           VL+HL++ L+R  FFM +   P+A SLY QF + Q L+ +++++ Q+DN  E+G   I  
Sbjct: 182 VLIHLRDNLDRSQFFMMIHTMPIAFSLYIQFLRVQNLEMVENMWEQEDNPLEMGFTKIIR 361

Query: 637 SYAAEERIEGRVAALQTAADAFYKAKNEFAAKATEDQMRLLRIQRRLEDELGGRFLDLSL 696
           +Y  +E ++ RV  L+ + + F++  + F  K  E++ +LLR QRRLEDE G  F+DLSL
Sbjct: 362 AY-DQETLDARVRLLEESGNCFHRVNSTFNEKHCEEENKLLRHQRRLEDETGLTFVDLSL 538

Query: 697 HDTVTTLILGGHNKRAEQLARDFRIP 722
             T+  L + G    A++L ++F++P
Sbjct: 539 QQTMHKLTMEGSYISADKLRKEFKVP 616
>15444
          Length = 1009

 Score = 81.3 bits (199), Expect = 1e-15,   Method: Compositional matrix adjust.
 Identities = 47/133 (35%), Positives = 68/133 (51%)
 Frame = -2

Query: 703 LILGGHNKRAEQLARDFRIPXXXXXXXXXXXXXXXXXXXXXXXFXXXXXXPIGYLPFVEI 762
           L + G    A++L ++F++P                       F      PIG   FVE 
Sbjct: 987 LTMEGSYISADKLRKEFKVPDKRFWWMRVYALAESGSWDELEKFSRTKKPPIGMEAFVEA 808

Query: 763 CMKQHNKHEAKKYASRVGPEQKVKALLLVGDVAQAAEVAIEHRNETELSLVLSHCTGATD 822
           CMK HNK EA KY +RV  E KV++L+ VG + QAAE A E++NE EL+ VLS      D
Sbjct: 807 CMKHHNKSEAXKYLTRVSAEHKVRSLVRVGQLQQAAEQAFENKNEDELNYVLSKVK-VVD 631

Query: 823 GAIADKIQRARAQ 835
             +A+ +++  +Q
Sbjct: 630 RQLAEAVRQMISQ 592
>30042
          Length = 818

 Score = 30.4 bits (67), Expect = 3.3,   Method: Composition-based stats.
 Identities = 18/58 (31%), Positives = 30/58 (51%), Gaps = 3/58 (5%)
 Frame = +2

Query: 247 TASLKEKLCEFNCNIRA---PPKQMVWCSRPRSKERAVVVAWERRLMVVGNAPESIQF 301
           + S++  +C  +  I A   P K++ W + PRS    +VV W RR  VV     +++F
Sbjct: 245 SVSVRCSICPHSIAILAQIWPVKRIDW-NPPRSDSNRIVVTWPRRQNVVAKLRRNLRF 415
>37432
          Length = 839

 Score = 25.8 bits (55), Expect(2) = 8.1,   Method: Composition-based stats.
 Identities = 13/28 (46%), Positives = 16/28 (57%)
 Frame = +2

Query: 27  WDLKEELKDCLVAAAPYGGPIALLRNCW 54
           WDL E LKD L  AA   G  +++  CW
Sbjct: 266 WDLNELLKDVLQYAAANPGSSSIM-CCW 346

 Score = 21.6 bits (44), Expect(2) = 8.1,   Method: Compositional matrix adjust.
 Identities = 8/16 (50%), Positives = 11/16 (68%)
 Frame = +1

Query: 14  SAFYRKHELYSMDWDL 29
           +A Y   ELY +DW+L
Sbjct: 148 NAGYTASELYDIDWNL 195
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|85861182|ref|NP_038495.2| aldehyde dehydrogenase 1A1
[Mus musculus]
         (501 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

11245                                                                 185   3e-47
27685                                                                 181   8e-46
31624                                                                 160   1e-39
25921                                                                 141   7e-34
25364                                                                  97   1e-20
31982                                                                  96   5e-20
26644                                                                  91   1e-18
18652                                                                  70   2e-12
28082                                                                  51   1e-06
01811                                                                  42   8e-04
11656                                                                  32   0.84 
17042                                                                  28   1.4  
09064                                                                  29   3.5  
12780                                                                  29   4.1  
>11245
          Length = 993

 Score =  185 bits (470), Expect = 3e-47,   Method: Compositional matrix adjust.
 Identities = 109/290 (37%), Positives = 164/290 (56%), Gaps = 2/290 (0%)
 Frame = +2

Query: 211 EAGFPPGVVNIVPGY-GPTAGAAISSHMDVDKVAFTGSTQVGKLIKEAAGKSNLKRVTLE 269
           EAG P GV+N+V        G       DV  ++FTGSTQVGKL+        +KRV LE
Sbjct: 2   EAGIPRGVINVVTTKKAAPIGELFCKSPDVRGISFTGSTQVGKLLFRNCA-DGIKRVCLE 178

Query: 270 LGGKSPCIVFADADLDIAVEFAHHGVFYHQGQCCVAASRIFVEESVYDEFVKRSVERAKK 329
           LGG +P IVF  A+++ AV+ A    F + GQ CV+A+R FV+E VYD+FV +  +R + 
Sbjct: 179 LGGNAPFIVFDSANVEKAVDGAMASKFRNCGQTCVSANRFFVQEGVYDKFVSQLKQRVEA 358

Query: 330 YVLGNPLTPGINQGPQIDKEQHDKILDLIESGKKEGAKLECGGGRWGNKG-FFVQPTVFS 388
             +G+  +  +  GP I+K Q DK+   +E  + + A +  GG      G  F  PT+ +
Sbjct: 359 LKIGDGKSSDVQIGPLINKMQFDKVSGFVEDARSKKANVIVGGKALQEFGSLFYAPTIVT 538

Query: 389 NVTDEMRIAKEEIFGPVQQIMKFKSVDDVIKRANNTTYGLAAGLFTKDLDKAITVSSALQ 448
           +V    ++  EE+FGPV  I+KFK   + + +AN+T  GLA   ++ +L +   V+  L+
Sbjct: 539 DVPPSAQLYTEEVFGPVVSIIKFKDEAEAVXQANDTQRGLAGYFYSDNLQQVFRVAKRLE 718

Query: 449 AGVVWVNCYMMLSAQCPFGGFKMSGNGRELGEHGLYEYTELKTVAMKISQ 498
            G+V VN  ++ + + PFGG K SG GRE   HG+ +Y ++K      SQ
Sbjct: 719 VGMVGVNEGIISAPEAPFGGVKESGIGREGSHHGIDDYVDIKIYMHGQSQ 868
>27685
          Length = 735

 Score =  181 bits (458), Expect = 8e-46,   Method: Compositional matrix adjust.
 Identities = 102/227 (44%), Positives = 132/227 (58%)
 Frame = +2

Query: 87  RLLNKLADLMERDRLLLATMEALNGGKVFANAYLSDLGGCIKALKYCAGWADKIHGQTIP 146
           ++L + A L++     LA ME L+ GK    A   D+ GC   ++Y  G    + G+   
Sbjct: 2   QVLTRAAILIQEREEELARMEVLDTGKPIWEARY-DIQGCADTIQYYGGIVPTLVGEHTK 178

Query: 147 SDGDIFTYTRREPIGVCGQIIPWNFPMLMFIWKIGPALSCGNTVVVKPAEQTPLTALHLA 206
             G  F YT REP+GV G I  WN+P  M  WK  PAL+CGNT+V KP+  TPLTA+ L 
Sbjct: 179 LSGGSFAYTLREPLGVVGAIGAWNYPFQMAAWKSSPALACGNTMVFKPSPFTPLTAVMLG 358

Query: 207 SLIKEAGFPPGVVNIVPGYGPTAGAAISSHMDVDKVAFTGSTQVGKLIKEAAGKSNLKRV 266
            + +EAG P G  N++ G G T G  IS H D+ K++FTGS   G  I  AA    +K V
Sbjct: 359 EIYREAGLPDGCYNVIQGEGET-GQLISHHDDIAKMSFTGSVATGSKIM-AACAQGIKHV 532

Query: 267 TLELGGKSPCIVFADADLDIAVEFAHHGVFYHQGQCCVAASRIFVEE 313
           TLELGGKSP I+F DADLD AV+ A    F  QGQ C   +R+FV+ 
Sbjct: 533 TLELGGKSPLIIFEDADLDNAVKGAMLANFLSQGQVCSNGTRVFVQR 673
>31624
          Length = 2324

 Score =  160 bits (405), Expect = 1e-39,   Method: Compositional matrix adjust.
 Identities = 105/313 (33%), Positives = 156/313 (49%), Gaps = 5/313 (1%)
 Frame = +1

Query: 143 QTIPSDGDIFTYTRREPIGVCGQIIPWNFPMLMFIWKIGPALSCGNTVVVKPAEQTPLTA 202
           Q I  D D  TY  R P+GV   I P+NFP ++ +W    A  CGNT ++KP+E+ P   
Sbjct: 4   QGIAKDMDTMTY--RLPLGVVAGITPFNFPAMIPLWMFPMAAVCGNTCILKPSERDPGAT 177

Query: 203 LHLASLIKEAGFPPGVVNIVPGYGPTAGAAISSHMDVDKVAFTGSTQVGKLIKEAAGKSN 262
           + L  L++EAG PPG+VN++ G   +    I  + D+  ++F GS Q G+ I E  G  N
Sbjct: 178 MILMELLQEAGMPPGIVNVIHGRHDSVN-FICDNPDIKAISFVGSDQAGEYIYE-RGSKN 351

Query: 263 LKRVTLELGGKSPCIVFADADLDIAVEFAHHGVFYHQGQCCVAASR-IFVEESVYDEFVK 321
            KRV   +G K+  ++  DA+ +  +       F   GQ C+A S  +FV E+   +++ 
Sbjct: 352 GKRVQANMGAKNHGVIMPDANKESTLTQLVGAAFGAAGQRCMALSTAVFVGEA--KKWIP 525

Query: 322 RSVERAKKYVLGNPLTPGINQGPQIDKEQHDKILDLIESGKKEGAKLECGGGRWG----N 377
             VERAK   +      G + GP I  E   ++ DL+++G   GA L   G         
Sbjct: 526 ELVERAKALKVTGGTEKGADLGPLISPESKKRVCDLVQAGVDAGADLLLDGRGVQVPGYE 705

Query: 378 KGFFVQPTVFSNVTDEMRIAKEEIFGPVQQIMKFKSVDDVIKRANNTTYGLAAGLFTKDL 437
           KG FV PT+   V   M+   EEIFGPV   M+  ++D+ I   N   YG    +FT + 
Sbjct: 706 KGNFVGPTILHQVDPNMKCYTEEIFGPVLVSMEVDTLDEAIDIVNANPYGNGTAIFTTNG 885

Query: 438 DKAITVSSALQAG 450
                V   ++ G
Sbjct: 886 GHGPQVHHGVRXG 924
>25921
          Length = 425

 Score =  141 bits (355), Expect = 7e-34,   Method: Compositional matrix adjust.
 Identities = 64/104 (61%), Positives = 82/104 (78%)
 Frame = +2

Query: 218 VVNIVPGYGPTAGAAISSHMDVDKVAFTGSTQVGKLIKEAAGKSNLKRVTLELGGKSPCI 277
           V+N++ G+GPTAGAAIS H D++KVAFTGS  VG++I EAA KSNLKR++LELGGKSP +
Sbjct: 2   VINVINGFGPTAGAAISEHPDINKVAFTGSVDVGRIIMEAAAKSNLKRISLELGGKSPVV 181

Query: 278 VFADADLDIAVEFAHHGVFYHQGQCCVAASRIFVEESVYDEFVK 321
           VF DAD+D AVE  H  +F + GQ C A SR +V E +YD+FV+
Sbjct: 182 VFDDADIDFAVETXHEALFSNHGQSCCAGSRTYVHEKIYDKFVE 313
>25364
          Length = 619

 Score = 97.4 bits (241), Expect = 1e-20,   Method: Compositional matrix adjust.
 Identities = 41/70 (58%), Positives = 58/70 (82%)
 Frame = +1

Query: 432 LFTKDLDKAITVSSALQAGVVWVNCYMMLSAQCPFGGFKMSGNGRELGEHGLYEYTELKT 491
           + TKD+DKA++++++LQAG VWVNC+ +++ Q PFGGFK SG GRELGE+ L EYTE+KT
Sbjct: 1   VITKDIDKALSLTNSLQAGSVWVNCFDIITPQTPFGGFKQSGQGRELGEYALKEYTEIKT 180

Query: 492 VAMKISQKNS 501
           V +K++ K S
Sbjct: 181 VTIKLASKTS 210
>31982
          Length = 555

 Score = 95.5 bits (236), Expect = 5e-20,   Method: Compositional matrix adjust.
 Identities = 43/113 (38%), Positives = 71/113 (62%), Gaps = 5/113 (4%)
 Frame = +2

Query: 363 KEGAKLECGGGRWG-----NKGFFVQPTVFSNVTDEMRIAKEEIFGPVQQIMKFKSVDDV 417
           K+GA++ CGG R       + G ++ P + +   D+M + +EE+FG V  ++ F + ++V
Sbjct: 2   KQGARVVCGGERVTPSAELSGGIYLSPCILTGCHDDMTVVQEEVFGSVLSVLTFDTQEEV 181

Query: 418 IKRANNTTYGLAAGLFTKDLDKAITVSSALQAGVVWVNCYMMLSAQCPFGGFK 470
           ++RAN+T  GLA G+FTKDL +A  V+  L+AG +++N Y +     PFGG+K
Sbjct: 182 VRRANBTELGLAGGIFTKDLKRAHQVAQQLEAGSLYINNYNVYPVGVPFGGYK 340
>26644
          Length = 396

 Score = 90.5 bits (223), Expect = 1e-18,   Method: Composition-based stats.
 Identities = 37/60 (61%), Positives = 51/60 (85%)
 Frame = -1

Query: 432 LFTKDLDKAITVSSALQAGVVWVNCYMMLSAQCPFGGFKMSGNGRELGEHGLYEYTELKT 491
           + TKD+DKA++++++LQAG VWVNC+ +++ Q PFGGFK SG GRELGE+ L EYTE+KT
Sbjct: 396 VITKDIDKALSLTNSLQAGSVWVNCFDIITPQTPFGGFKQSGQGRELGEYALKEYTEIKT 217
>18652
          Length = 759

 Score = 70.1 bits (170), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 47/169 (27%), Positives = 72/169 (42%), Gaps = 3/169 (1%)
 Frame = -1

Query: 334 NPLTPGINQGPQIDKEQHDKILDLIESGKKEGAKLECGGGRWGNKGFFVQPTVFSNVTDE 393
           +PL  G+N GP    +        +     +G K+E GG      G FV+PT+ S ++ +
Sbjct: 696 DPLDEGVNYGPLHSPQGVALFQQAVADAVAQGGKIEYGGKPIERPGNFVEPTIISGLSHD 517

Query: 394 MRIAKEEIFGPVQQIMKFKSVDDVIKRANNTTYGLAAGLFTKDLDKAITVSSALQAGVVW 453
             +   E F P+   +K  ++D+ I   N    GL + LFTKDL           +    
Sbjct: 516 APVVHRETFAPIVYALKTTNLDEAIAWNNEVKQGLTSSLFTKDLANVFKWIGPKGSDCGI 337

Query: 454 VNCYMMLSAQ---CPFGGFKMSGNGRELGEHGLYEYTELKTVAMKISQK 499
           VN  +  S       FGG K +G GRE G     +Y    T  +  S++
Sbjct: 336 VNVNIPTSGAEIGGAFGGEKHTGGGRESGSDAWKQYMRRSTCTINFSKE 190
>28082
          Length = 445

 Score = 51.2 bits (121), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 35/128 (27%), Positives = 61/128 (47%), Gaps = 1/128 (0%)
 Frame = -1

Query: 85  RGRLLNKLADLMERDRLLLATMEALNGGKVFANAYLSDLGGCIKALKYCAGWADKIHGQT 144
           RG ++ ++ D + + +  L  + +L  GK+++     ++   I    Y  G +    GQ 
Sbjct: 445 RGDIVRQIGDELRKYKEPLGKLVSLEVGKIYSEGQ-GEVQEFIDICDYAVGLSRIYAGQL 269

Query: 145 IPSDGDIFTYTRR-EPIGVCGQIIPWNFPMLMFIWKIGPALSCGNTVVVKPAEQTPLTAL 203
           I S+    T      P+G+ G I  +NFP  +F W    AL  GN+V+ K A  TPL ++
Sbjct: 268 INSERVEHTILEAWRPLGLVGVISAYNFPNAVFGWNAAIALITGNSVLWKGAPSTPLVSV 89

Query: 204 HLASLIKE 211
               ++ E
Sbjct: 88  ATTRIVAE 65
>01811
          Length = 1288

 Score = 41.6 bits (96), Expect = 8e-04,   Method: Compositional matrix adjust.
 Identities = 26/84 (30%), Positives = 40/84 (47%), Gaps = 2/84 (2%)
 Frame = +2

Query: 399 EEIFGPVQQIMKFKSVDDVIKRANNTTYGLAAGLFTKDLDKAITVSSALQAGVVWVNCYM 458
           EE+FGP+  IM  K   + ++   +    LA  +F+ + D   T+     +G + VN  +
Sbjct: 2   EEVFGPLLPIMVVKDHHEAVQVITDKEKPLAMYVFSNNSDVVRTLKEGSSSGAILVNDTI 181

Query: 459 MLSAQC--PFGGFKMSGNGRELGE 480
           M    C  PFGG   SG G   G+
Sbjct: 182 MHGGLCTLPFGGVGESGMGSYHGK 253
>11656
          Length = 1215

 Score = 31.6 bits (70), Expect = 0.84,   Method: Compositional matrix adjust.
 Identities = 23/84 (27%), Positives = 41/84 (48%), Gaps = 2/84 (2%)
 Frame = +2

Query: 401 IFGPVQQIMKFKSVDDVIKRANNTTYGLAAGLFTKDLDKAITVSSALQAGVVWVNCYMML 460
            + P Q++++  ++D++I           + +F  +L      ++ LQ G  W N   +L
Sbjct: 44  FYTPSQELVERYNLDNLI----------VSNMFKSEL--PFLTATQLQQGWAWANNVNLL 187

Query: 461 S--AQCPFGGFKMSGNGRELGEHG 482
           +  A  P GG  M+G+G   GEHG
Sbjct: 188 ASGASLPHGG--MTGSGIYAGEHG 253
>17042
          Length = 864

 Score = 27.7 bits (60), Expect(2) = 1.4,   Method: Compositional matrix adjust.
 Identities = 12/34 (35%), Positives = 21/34 (61%)
 Frame = +3

Query: 464 CPFGGFKMSGNGRELGEHGLYEYTELKTVAMKIS 497
           CP    K +G GRE G   L  Y+++K+V ++++
Sbjct: 36  CPSAATKSTGIGRENGPDTLDYYSQIKSVYVEMN 137

 Score = 21.6 bits (44), Expect(2) = 1.4,   Method: Compositional matrix adjust.
 Identities = 7/18 (38%), Positives = 11/18 (61%)
 Frame = +2

Query: 453 WVNCYMMLSAQCPFGGFK 470
           ++N Y +     PFGG+K
Sbjct: 2   YINNYNVYPVGVPFGGYK 55
>09064
          Length = 473

 Score = 29.3 bits (64), Expect = 3.5,   Method: Composition-based stats.
 Identities = 11/24 (45%), Positives = 16/24 (66%)
 Frame = +3

Query: 194 PAEQTPLTALHLASLIKEAGFPPG 217
           P++ +PLT  H +SL+  A  PPG
Sbjct: 30  PSKYSPLTRTHFSSLLSHAQSPPG 101
>12780
          Length = 598

 Score = 29.3 bits (64), Expect = 4.1,   Method: Compositional matrix adjust.
 Identities = 19/64 (29%), Positives = 32/64 (50%), Gaps = 6/64 (9%)
 Frame = +3

Query: 205 LASLIKEAGFPPGVVNIVPGYGPTAGAAISSHMDVDKVAFTGSTQ------VGKLIKEAA 258
           +A+ +  A   P V+++VP  G    A + +H+D+ +V  TG T       V   +KEA 
Sbjct: 207 VANKLGHATTDPAVIHLVPVVGVHGYALVQTHLDITRVLITG*TVNVVIFIVTASVKEAG 386

Query: 259 GKSN 262
             +N
Sbjct: 387 *ATN 398
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|164565394|ref|NP_766292.2| DnaJ (Hsp40) homolog,
subfamily C, member 11 [Mus musculus]
         (559 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

18150                                                                 164   4e-47
34065                                                                 148   5e-36
02324                                                                  66   3e-11
14550                                                                  66   4e-11
26984                                                                  59   4e-09
02088                                                                  56   4e-08
13998                                                                  54   1e-07
07620                                                                  42   2e-07
13422                                                                  46   5e-05
22505                                                                  33   3e-04
15360                                                                  40   0.002
33510                                                                  33   0.22 
>18150
          Length = 768

 Score =  164 bits (416), Expect(2) = 4e-47,   Method: Compositional matrix adjust.
 Identities = 90/217 (41%), Positives = 125/217 (57%), Gaps = 2/217 (0%)
 Frame = +2

Query: 64  QAYEVLSDPQTRAIYDIYGKRGLEMEGWEVVERKRTPAXXXXXXXXXXXXXXXXXXXXXT 123
           +A+E+LSD   R IYD YG++GLE EG E++ R ++PA                     T
Sbjct: 119 EAHEILSDKHKRTIYDTYGEKGLETEGLEIISRTKSPAEIIAEYERLQREREERRLQQRT 298

Query: 124 NPKGTISVGVDATDLFDRYDEEYEDV--SGSGFPQIEINKMHISQSIEAPLTATDTAILS 181
           NP+GT+S+G++ATDLFD Y  + +D    G     IEI+ M I QS+E PLT  DT I+ 
Sbjct: 299 NPRGTVSLGINATDLFDNYGHDDDDDIYYGPSATSIEISNMSIFQSVECPLTLKDTVIIG 478

Query: 182 GSLSTQNGNGGGSVNFALRRVTSAKGWGELEFGAGDLQGPLFGLKLFRNLTPRCFVTTNC 241
           G+L  +NG G G+     RR+TS KGW E+E  AG   G  F LK FR LT RC+ T++ 
Sbjct: 479 GNLQARNGTGAGAFLATWRRLTSDKGWMEIETAAGSGLG--FSLKGFRQLTRRCYGTSSL 652

Query: 242 ALQFSSRGIRPGLTTVLARNLDKNTVGYLQWRWGIQS 278
            L  + +GIRP L+T++A   D+   G + +  G  S
Sbjct: 653 TLHSTPKGIRPSLSTMVAYQFDRELQGRITYNAGFPS 763

 Score = 42.4 bits (98), Expect(2) = 4e-47,   Method: Compositional matrix adjust.
 Identities = 18/36 (50%), Positives = 25/36 (69%)
 Frame = +3

Query: 25 ASSEELKAAYRRLCMLYHPDKHRDPELKSQAERLFN 60
          A++EE+  A+RRL  +YHPDKH +   K  AE +FN
Sbjct: 3  ATTEEVNNAFRRLSKIYHPDKHLEAAKKKAAEDMFN 110
>34065
          Length = 811

 Score =  148 bits (374), Expect = 5e-36,   Method: Compositional matrix adjust.
 Identities = 75/146 (51%), Positives = 105/146 (71%), Gaps = 2/146 (1%)
 Frame = +2

Query: 410 PYLRAQKE-KELEKQRENTASDILQKKQEAEAAVRLMQESVRRIIEAEESRMGLIIVNAW 468
           P+L+ QKE ++ +++RE  A  + +KKQEA+ A  LM+E+V R ++AEE +MGL+I+ A 
Sbjct: 11  PFLKQQKETRDWKRKREEHADKLAKKKQEAKTATELMKETVERNVDAEEKKMGLVIIKAL 190

Query: 469 YGKFVNDKSRKNEKVKVIDVTVPLQCLVKDSKLILTEA-SKAGLPGFYDPCVGEEKSLRV 527
           YGK       +    + IDVTV LQ LVKDSKLI+ +A SK+GLPGFYDPC+GEEK+L +
Sbjct: 191 YGKLQASDDGELIDRECIDVTVQLQALVKDSKLIVPDAVSKSGLPGFYDPCIGEEKTLYI 370

Query: 528 LYQFRGVLHQVMVPDSEALRIPKQSH 553
            Y+FR  LHQV + D E +R+P+Q H
Sbjct: 371 RYKFRNRLHQVTLSDLEVIRLPQQKH 448
>02324
          Length = 2058

 Score = 66.2 bits (160), Expect = 3e-11,   Method: Compositional matrix adjust.
 Identities = 31/65 (47%), Positives = 45/65 (69%)
 Frame = +2

Query: 15  YYSLLNVRREASSEELKAAYRRLCMLYHPDKHRDPELKSQAERLFNLVHQAYEVLSDPQT 74
           +Y +L V R A +++LK AYR+L + +HPDK+  P+   +A   F LV QAYE+L+DPQ 
Sbjct: 107 HYEVLGVERSADNDDLKKAYRKLALKFHPDKN--PDSVEEATAQFRLVQQAYEILTDPQE 280

Query: 75  RAIYD 79
           R+ YD
Sbjct: 281 RSWYD 295
>14550
          Length = 1395

 Score = 65.9 bits (159), Expect = 4e-11,   Method: Compositional matrix adjust.
 Identities = 34/80 (42%), Positives = 51/80 (63%), Gaps = 1/80 (1%)
 Frame = -1

Query: 10   LDNEDYYSLLNVRREASSEELKAAYRRLCMLYHPDKHR-DPELKSQAERLFNLVHQAYEV 68
            L   D+Y +L V + A ++++K AYR++    HPDK+R DPE    AE+ F  +  AYEV
Sbjct: 1146 LGGRDFYKILGVSKSADTKQIKRAYRKIAKELHPDKNRDDPE----AEQRFQDLGAAYEV 979

Query: 69   LSDPQTRAIYDIYGKRGLEM 88
            LSD + R +YD +G+ GL+ 
Sbjct: 978  LSDEEKRKVYDRHGEEGLKQ 919
>26984
          Length = 1107

 Score = 59.3 bits (142), Expect = 4e-09,   Method: Compositional matrix adjust.
 Identities = 28/69 (40%), Positives = 44/69 (63%)
 Frame = -2

Query: 13  EDYYSLLNVRREASSEELKAAYRRLCMLYHPDKHRDPELKSQAERLFNLVHQAYEVLSDP 72
           +D YS+L +R +AS E++K  YRR  +L HPDK+++P     AE  F ++  A+E++ DP
Sbjct: 518 KDPYSILGLRADASDEDIKRYYRRQAVLVHPDKNQEP----GAEEAFKILGHAFEMIGDP 351

Query: 73  QTRAIYDIY 81
             R  YD +
Sbjct: 350 TKRKEYDTH 324
>02088
          Length = 1062

 Score = 56.2 bits (134), Expect = 4e-08,   Method: Compositional matrix adjust.
 Identities = 31/81 (38%), Positives = 45/81 (55%)
 Frame = +3

Query: 7   EEELDNEDYYSLLNVRREASSEELKAAYRRLCMLYHPDKHRDPELKSQAERLFNLVHQAY 66
           EE  +  D Y ++ +RREA+ +E+K  Y ++ +  HPD+    E K  A R F  + + Y
Sbjct: 87  EELFETTDLYEVIGIRREATPQEVKKGYHKVSLAVHPDQVSAAE-KETATRKFQTLGKVY 263

Query: 67  EVLSDPQTRAIYDIYGKRGLE 87
            VLSD   RA YD  G+ G E
Sbjct: 264 TVLSDKDKRAXYDETGEVGEE 326
>13998
          Length = 1075

 Score = 53.9 bits (128), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 25/69 (36%), Positives = 43/69 (62%), Gaps = 2/69 (2%)
 Frame = +1

Query: 13  EDYYSLLNVRREASSEELKAAYRRLCMLYHPDKHRD--PELKSQAERLFNLVHQAYEVLS 70
           +DYY +L + R A+ +E+K AYR+  +++HPD+H +   +++   E  F  V +AY +LS
Sbjct: 202 KDYYKILGISRNATEDEIKKAYRKKALVHHPDRHANSSADVRKDEELKFKEVGEAYAILS 381

Query: 71  DPQTRAIYD 79
           D   +  YD
Sbjct: 382 DGAKKTRYD 408
>07620
          Length = 1775

 Score = 42.4 bits (98), Expect(2) = 2e-07,   Method: Compositional matrix adjust.
 Identities = 16/41 (39%), Positives = 30/41 (73%), Gaps = 2/41 (4%)
 Frame = +1

Query: 13  EDYYSLLNVRREASSEELKAAYRRLCMLYHPDK--HRDPEL 51
           +DYY +L+V+++ +  ++K AYR+L +  HPDK  H++P +
Sbjct: 97  KDYYEVLDVKKDCTESDMKKAYRKLALQMHPDKTRHQEPXM 219

 Score = 31.2 bits (69), Expect(2) = 2e-07,   Method: Compositional matrix adjust.
 Identities = 13/24 (54%), Positives = 15/24 (62%)
 Frame = +3

Query: 59  FNLVHQAYEVLSDPQTRAIYDIYG 82
           F  +  AY VLSDP  R  YD+YG
Sbjct: 222 FKKIGNAYSVLSDPDKRRKYDVYG 293
>13422
          Length = 930

 Score = 45.8 bits (107), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 26/81 (32%), Positives = 46/81 (56%), Gaps = 5/81 (6%)
 Frame = +1

Query: 4   ALSEEELDNEDYYSLL---NVRREASSEELKAAYRRLCMLYHPDKHRDPELKSQ--AERL 58
            L+ +E   +D+Y++L    +R +A+++ +K  YR+  +L+HPDK R   L  +      
Sbjct: 307 GLNPKEWKKQDHYAVLGLSKLRYKATADHIKRIYRQKVLLHHPDKRRARGLHVENGENDY 486

Query: 59  FNLVHQAYEVLSDPQTRAIYD 79
           F  + +AYE+L DP  R  +D
Sbjct: 487 FLCISRAYEILGDPVKRRSFD 549
>22505
          Length = 784

 Score = 33.1 bits (74), Expect(2) = 3e-04,   Method: Compositional matrix adjust.
 Identities = 15/40 (37%), Positives = 25/40 (62%)
 Frame = -1

Query: 6   SEEELDNEDYYSLLNVRREASSEELKAAYRRLCMLYHPDK 45
           S+E++   D Y +L V  EA+ +++  AYR+  +  HPDK
Sbjct: 676 SKEDIMKMDLYGILGVGPEANEKQIVKAYRKKALKCHPDK 557

 Score = 28.9 bits (63), Expect(2) = 3e-04,   Method: Compositional matrix adjust.
 Identities = 12/26 (46%), Positives = 18/26 (69%)
 Frame = -3

Query: 54  QAERLFNLVHQAYEVLSDPQTRAIYD 79
           +A  LF+ + +A EVL+DP  +A YD
Sbjct: 542 KAAELFHELSKALEVLTDPSAKAAYD 465
>15360
          Length = 502

 Score = 40.4 bits (93), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 21/68 (30%), Positives = 41/68 (60%)
 Frame = +1

Query: 10  LDNEDYYSLLNVRREASSEELKAAYRRLCMLYHPDKHRDPELKSQAERLFNLVHQAYEVL 69
           L  E  ++LL++   +  E LK  Y++L + +HP+KH++    ++A + F  V QAY +L
Sbjct: 43  LTREAAFNLLDIPAGSDQESLKTKYKQLALKWHPEKHKNA---AEAVKQFIQVTQAYRLL 213

Query: 70  SDPQTRAI 77
           +   ++A+
Sbjct: 214 AYNTSQAM 237
>33510
          Length = 501

 Score = 33.5 bits (75), Expect = 0.22,   Method: Composition-based stats.
 Identities = 16/68 (23%), Positives = 35/68 (51%)
 Frame = +3

Query: 11  DNEDYYSLLNVRREASSEELKAAYRRLCMLYHPDKHRDPELKSQAERLFNLVHQAYEVLS 70
           D+E  +    +    S++++K  YR+  +  HPDK  D   ++ A+ +F  ++ A+    
Sbjct: 249 DSESRWKPCGMHDLVSADQVKKVYRKAVLSVHPDKLHDDPHEALAKLIFMELNDAWAKFE 428

Query: 71  DPQTRAIY 78
           D   +++Y
Sbjct: 429 DEGMKSLY 452
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31981269|ref|NP_075629.2| glutaredoxin 3 [Mus
musculus]
         (337 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

11167                                                                 184   4e-47
02801                                                                 163   9e-41
18455                                                                  45   4e-05
06936                                                                  42   5e-04
03582                                                                  39   0.003
28335                                                                  37   0.013
24513                                                                  32   0.42 
27515                                                                  31   0.81 
15159                                                                  31   0.81 
>11167
          Length = 485

 Score =  184 bits (467), Expect = 4e-47,   Method: Compositional matrix adjust.
 Identities = 86/161 (53%), Positives = 119/161 (73%), Gaps = 6/161 (3%)
 Frame = -3

Query: 35  LLVVHFWAPWAPQCVQMNDVMAELAKE--HPHVSFVKLEAEAVPEVSEKYEISSVPTFLF 92
           L+VVHFW  WAPQC QM+DVM ELA +  + +V FV++ AE + +VS++Y I +VPTF+F
Sbjct: 483 LVVVHFWTDWAPQCAQMDDVMKELASDMHYVNVVFVRVAAEDLADVSQRYNIVAVPTFIF 304

Query: 93  FKNSQKVDRLDGAHAPELTKKVQRHVS----SGAFPPSTNEHLKEDLSLRLKKLTHAAPC 148
            K   +VDR+DGA A ELT+KV RHVS    +G  P +      EDL+ RLK+L ++AP 
Sbjct: 303 LKGKDQVDRIDGAKAAELTEKVGRHVSNVSLTGPVPQTKAPAKPEDLNSRLKQLINSAPV 124

Query: 149 MLFMKGTPQEPRCGFSKQMVEILHKHNIQFSSFDIFSDEEV 189
           MLFMKG P +PRCGFSKQ V++L++ N+++S+FDI +D+EV
Sbjct: 123 MLFMKGNPDQPRCGFSKQTVQLLNERNVKYSTFDILTDDEV 1

 Score = 73.9 bits (180), Expect = 9e-14,   Method: Compositional matrix adjust.
 Identities = 36/64 (56%), Positives = 44/64 (68%), Gaps = 1/64 (1%)
 Frame = -3

Query: 229 TICPKAPK-LEERLKVLTNKASVMLFMKGNKQEAKCGFSKQILEILNSTGVEYETFDILE 287
           T  P  P+ L  RLK L N A VMLFMKGN  + +CGFSKQ +++LN   V+Y TFDIL 
Sbjct: 192 TKAPAKPEDLNSRLKQLINSAPVMLFMKGNPDQPRCGFSKQTVQLLNERNVKYSTFDILT 13

Query: 288 DEEV 291
           D+EV
Sbjct: 12  DDEV 1
>02801
          Length = 1160

 Score =  163 bits (412), Expect = 9e-41,   Method: Compositional matrix adjust.
 Identities = 78/120 (65%), Positives = 94/120 (78%)
 Frame = +1

Query: 210 ELIGGLDIIKELEASEELDTICPKAPKLEERLKVLTNKASVMLFMKGNKQEAKCGFSKQI 269
           EL+GGLDI+KE+  S EL    P    L+ RLK L N+A +MLFMKG     +CGFSK  
Sbjct: 1   ELLGGLDILKEMAESGELADALPVQQDLDTRLKALINQAPIMLFMKGCPDTPRCGFSKTT 180

Query: 270 LEILNSTGVEYETFDILEDEEVRQGLKTFSNWPTYPQLYVRGDLVGGLDIVKELKDNGEL 329
           ++ILN TGV+Y+TFDIL DEEVRQGLK FSNWPTYPQLYV G+L+GGLDI+KE+K+NGEL
Sbjct: 181 IQILNDTGVKYQTFDILGDEEVRQGLKKFSNWPTYPQLYVHGELLGGLDIIKEMKENGEL 360

 Score =  136 bits (343), Expect = 1e-32,   Method: Compositional matrix adjust.
 Identities = 60/97 (61%), Positives = 76/97 (78%)
 Frame = +1

Query: 131 LKEDLSLRLKKLTHAAPCMLFMKGTPQEPRCGFSKQMVEILHKHNIQFSSFDIFSDEEVR 190
           +++DL  RLK L + AP MLFMKG P  PRCGFSK  ++IL+   +++ +FDI  DEEVR
Sbjct: 70  VQQDLDTRLKALINQAPIMLFMKGCPDTPRCGFSKTTIQILNDTGVKYQTFDILGDEEVR 249

Query: 191 QGLKTYSNWPTYPQLYVSGELIGGLDIIKELEASEEL 227
           QGLK +SNWPTYPQLYV GEL+GGLDIIKE++ + EL
Sbjct: 250 QGLKKFSNWPTYPQLYVHGELLGGLDIIKEMKENGEL 360
>18455
          Length = 499

 Score = 45.1 bits (105), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 19/72 (26%), Positives = 38/72 (52%), Gaps = 3/72 (4%)
 Frame = +2

Query: 38  VHFWAPWAPQCVQMNDVMAELAK---EHPHVSFVKLEAEAVPEVSEKYEISSVPTFLFFK 94
           V F+APW   C ++  +  ELAK   + P  +  K++      + + +E+   PT L+ +
Sbjct: 203 VKFFAPWCSHCQRLAPIWEELAKALIKEPSATISKIDCTQYRSICQDFEVKGYPTLLWIE 382

Query: 95  NSQKVDRLDGAH 106
           + +K+++  GA 
Sbjct: 383 DGKKIEKYAGAR 418
>06936
          Length = 2198

 Score = 41.6 bits (96), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 24/75 (32%), Positives = 37/75 (49%), Gaps = 3/75 (4%)
 Frame = +3

Query: 21   AQQFEELLRLKTKSLLVVHFWAPWAPQCVQMN---DVMAELAKEHPHVSFVKLEAEAVPE 77
             + FEEL+    K +L+  F+APW   C  +    D +AE  K  P +   K++A A  +
Sbjct: 1206 GRNFEELVNDPEKDVLI-EFYAPWCGHCKTLAPKYDELAEKLKNEPEIVIAKMDATA-ND 1379

Query: 78   VSEKYEISSVPTFLF 92
            V   Y++   PT  F
Sbjct: 1380 VPPPYDVRGFPTLYF 1424
>03582
          Length = 1967

 Score = 38.9 bits (89), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 33/110 (30%), Positives = 55/110 (50%), Gaps = 5/110 (4%)
 Frame = +3

Query: 21   AQQFEELLRLKTKSLLVVHFWAPWAPQCVQMNDVMAELAK---EHPHVSFVKLEAEAVPE 77
             + F+E+   KTK + V  F+APW   C Q+  +  ELA    +   V   K+++ A  E
Sbjct: 1146 GKNFKEVALDKTKGVFV-EFYAPWCGHCKQLAPIWDELADKFTDKADVVIAKMDSTA-NE 1319

Query: 78   VSEKYEISSVPTFLFF-KNSQKVDRLDGAHAPE-LTKKVQRHVSSGAFPP 125
            + E+ ++ S PT  +F K+S +V   +G    +   K V+   + GA  P
Sbjct: 1320 I-EEVKVQSFPTLKYFPKDSDEVIDYNGERTLDAFVKFVESGGTEGAGVP 1466
>28335
          Length = 601

 Score = 36.6 bits (83), Expect = 0.013,   Method: Compositional matrix adjust.
 Identities = 21/75 (28%), Positives = 36/75 (48%), Gaps = 3/75 (4%)
 Frame = -2

Query: 21  AQQFEELLRLKTKSLLVVHFWAPWAPQCVQMNDVMAELA---KEHPHVSFVKLEAEAVPE 77
            + F++++    K +L+  F+APW   C Q+     ELA   K+ P +   K++A A  +
Sbjct: 531 GRTFDKIVNNPKKDVLI-EFYAPWCGHCQQLEPKYNELATLLKDEPDIVXAKIDATAN-D 358

Query: 78  VSEKYEISSVPTFLF 92
               YE+   P   F
Sbjct: 357 TPTPYEVKGFPAIYF 313
>24513
          Length = 901

 Score = 31.6 bits (70), Expect = 0.42,   Method: Compositional matrix adjust.
 Identities = 14/38 (36%), Positives = 19/38 (50%)
 Frame = -3

Query: 140 KKLTHAAPCMLFMKGTPQEPRCGFSKQMVEILHKHNIQ 177
              TH    + F K T  EP+ GF    VE+L+  NI+
Sbjct: 416 NNFTHQVSLLFFSKRTT*EPQTGFQNPGVEVLNDQNIE 303
>27515
          Length = 473

 Score = 30.8 bits (68), Expect = 0.81,   Method: Compositional matrix adjust.
 Identities = 16/49 (32%), Positives = 23/49 (46%)
 Frame = +1

Query: 253 FMKGNKQEAKCGFSKQILEILNSTGVEYETFDILEDEEVRQGLKTFSNW 301
           F  GN     C     + +I+ STG  YE  + L    +R+   TFS+W
Sbjct: 139 FTTGNNVTGLCIDQNNVNKIVTSTGPPYELMNSLLPLYMRKXYMTFSSW 285
>15159
          Length = 1945

 Score = 30.8 bits (68), Expect = 0.81,   Method: Compositional matrix adjust.
 Identities = 13/35 (37%), Positives = 22/35 (62%)
 Frame = +2

Query: 86  SVPTFLFFKNSQKVDRLDGAHAPELTKKVQRHVSS 120
           S    LFF++ +K+D L GA+  +L   +++HV S
Sbjct: 296 SHANILFFRDGKKIDELVGANHEKLLLMIEKHVDS 400
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|96975138|ref|NP_038584.2| hypoxanthine guanine
phosphoribosyl transferase 1 [Mus musculus]
         (218 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

36029                                                                 134   7e-47
14312                                                                  27   6.5  
>36029
          Length = 658

 Score =  134 bits (336), Expect(2) = 7e-47,   Method: Compositional matrix adjust.
 Identities = 65/88 (73%), Positives = 76/88 (86%)
 Frame = +2

Query: 93  IPMTVDFIRLKSYCNDQSTGDIKVIGGDDLSTLTGKNVLIVEDIIDTGKTMQTLLSLVKQ 152
           +PM+VDFIRLKSY ND+S+G I+VIGGD+L +L GKNVL+VEDIIDTGKTMQ LLSL+  
Sbjct: 2   VPMSVDFIRLKSYQNDKSSGSIEVIGGDNLESLKGKNVLVVEDIIDTGKTMQQLLSLLYA 181

Query: 153 YSPKMVKVASLLVKRTSRSVGYRPDFVG 180
             PK VKVASLLVKRT RS GYRPD++G
Sbjct: 182 VEPKCVKVASLLVKRTERSSGYRPDYMG 265

 Score = 70.5 bits (171), Expect(2) = 7e-47,   Method: Compositional matrix adjust.
 Identities = 31/37 (83%), Positives = 34/37 (91%)
 Frame = +3

Query: 180 GFEIPDKFVVGYALDYNEYFRDLNHVCVISETGKAKY 216
           GFEIPD+FVVGYALDYNEYFRDLNH+ VI+E GK KY
Sbjct: 264 GFEIPDRFVVGYALDYNEYFRDLNHIGVINEVGKKKY 374
>14312
          Length = 1773

 Score = 26.9 bits (58), Expect = 6.5,   Method: Compositional matrix adjust.
 Identities = 9/26 (34%), Positives = 18/26 (69%)
 Frame = +3

Query: 86  NRNSDRSIPMTVDFIRLKSYCNDQST 111
           N+NS++S  + V +++ +  CND S+
Sbjct: 972 NKNSEKSTNLIVQWVKYRRTCNDASS 1049
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|171184428|ref|NP_035940.3| Fas apoptotic inhibitory
molecule Faim-S [Mus musculus]
         (179 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

03311                                                                 182   8e-47
27027                                                                  28   2.1  
15014                                                                  27   4.4  
>03311
          Length = 1729

 Score =  182 bits (461), Expect = 8e-47,   Method: Compositional matrix adjust.
 Identities = 91/141 (64%), Positives = 110/141 (78%), Gaps = 2/141 (1%)
 Frame = -2

Query: 38   EEIRR-EWMFKLVGKETFFVGAAKTKATINIDAISGFAYEYTLEIDGKSLKKYMENRSKT 96
            EEI R +WMFKLVG+E F V    TK TI+IDA+SGFAYEYTL+++GK LKK+ EN+SK 
Sbjct: 1728 EEIYRVDWMFKLVGREHFTVSG--TKCTISIDAVSGFAYEYTLDVNGKPLKKFQENKSKI 1555

Query: 97   TSTWVLRLDGEDLRVVLEKDTMDVWCNGQKMETAGEFVDDGTETHFSV-GNHGCYIKAVS 155
              TWV  + GE  R+VLEKDT+D+W NGQK E+ GEFVDDGTETHF +  +H   IKA S
Sbjct: 1554 MRTWVAYVAGEPTRIVLEKDTLDIWVNGQKKESTGEFVDDGTETHFEIDSSHAGIIKATS 1375

Query: 156  SGKRKEGIIHTLIVDNREIPE 176
            SGKRK+GIIHTL ++N EIPE
Sbjct: 1374 SGKRKDGIIHTLFINNAEIPE 1312
>27027
          Length = 504

 Score = 28.1 bits (61), Expect = 2.1,   Method: Compositional matrix adjust.
 Identities = 18/56 (32%), Positives = 23/56 (41%)
 Frame = -3

Query: 64  TINIDAISGFAYEYTLEIDGKSLKKYMENRSKTTSTWVLRLDGEDLRVVLEKDTMD 119
           T  I  ++GF Y   L     SL K   N S T  TW       D R  +E + +D
Sbjct: 340 TSGIH*LAGFYYRLCLRA*AGSLTKSAHNASPTHRTWATGDHSRD-RATIESNFLD 176
>15014
          Length = 454

 Score = 26.9 bits (58), Expect = 4.4,   Method: Compositional matrix adjust.
 Identities = 14/42 (33%), Positives = 21/42 (50%)
 Frame = -2

Query: 97  TSTWVLRLDGEDLRVVLEKDTMDVWCNGQKMETAGEFVDDGT 138
           TS   +R+D E   V    D+  +W  G K+   GE + DG+
Sbjct: 369 TSGISVRIDQESQNVSNRSDS*PLWNRGTKISLGGEEIKDGS 244
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|45387933|ref|NP_942602.1| UDP-glucose ceramide
glucosyltransferase-like 1 [Mus musculus]
         (1551 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

27286                                                                 186   8e-47
11868                                                                 171   3e-42
34894                                                                 112   9e-25
33097                                                                  32   1.5  
>27286
          Length = 454

 Score =  186 bits (471), Expect = 8e-47,   Method: Compositional matrix adjust.
 Identities = 84/143 (58%), Positives = 105/143 (73%)
 Frame = -2

Query: 1017 NLRVFMNCQSKLSDMPLKSFYRYVLEPEISFTADSSFAKGPIAKFLDMPQSPLFTLNLNT 1076
            ++RV+MNC+ +LSDMP+K FYRYVLEPE+ F +D    +G  A+FLD+P   L TL +  
Sbjct: 429  DIRVYMNCRMQLSDMPVKRFYRYVLEPELEFRSDGERTEGATARFLDLPHKSLLTLGMEP 250

Query: 1077 PESWMVQSVRTPYDLDNIYLEEVDSIVAAXXXXXXXXXXGHCYDITTGQPPRGLQFTLGT 1136
            PESW+V+SV + YDLDNI LEEV+  + A          GHCYD  T QPPRGLQF LGT
Sbjct: 249  PESWLVESVSSVYDLDNILLEEVEKSINAGFELEYILLEGHCYDSNTMQPPRGLQFILGT 70

Query: 1137 SANPTIVDTIVMANLGYFQLKAN 1159
            ++NP +VDTIVMANLGYFQLKA+
Sbjct: 69   ASNPAVVDTIVMANLGYFQLKAS 1
>11868
          Length = 574

 Score =  171 bits (432), Expect = 3e-42,   Method: Compositional matrix adjust.
 Identities = 77/92 (83%), Positives = 86/92 (93%)
 Frame = +1

Query: 1432 DRLRGQYQGLSQDPNSLSNLDQDLPNNMIHQVPIKSLPQEWLWCETWCDDASKKRAKTID 1491
            DRLRGQYQGLSQDPNSLSNLDQDLPNNMIHQV IKSLPQEWL+CETWC ++ K +AKTID
Sbjct: 1    DRLRGQYQGLSQDPNSLSNLDQDLPNNMIHQVAIKSLPQEWLYCETWCSESQKSKAKTID 180

Query: 1492 LCNNPMTKEPKLEAAVRIVPEWQDYDQEIKQL 1523
            LCNNP+TKEPKL+AA+RIVPEW++YD EIK L
Sbjct: 181  LCNNPLTKEPKLQAAMRIVPEWKNYDYEIKVL 276
>34894
          Length = 424

 Score =  112 bits (281), Expect = 9e-25,   Method: Composition-based stats.
 Identities = 56/135 (41%), Positives = 78/135 (57%)
 Frame = -3

Query: 843 AAGVDIAEFSVGGMDVSLFKEVFESSRMDFILSHALYCRDVLKLKKGQRVVISNGRIIGP 902
           A    + +F V GMD+  +    ES +  F+ SHA +   VL    GQR ++ NG++ GP
Sbjct: 407 AGSKTLRDFEVNGMDMDSYMRAVESEKGQFLQSHAAFTSHVLGFTAGQRAIVVNGKVFGP 228

Query: 903 LEDNELFNQDDFHLLENIILKTSGQKIKSHIQQLRVEEDVASDLVMKVDALLSAQPKGEA 962
           LE  E F  DDF LLE ++   SG K++  +Q + +E +  SD+VMKV ALLS Q   EA
Sbjct: 227 LEPKESFTPDDFGLLEKLVSVQSGTKLRQQVQGVGIEGNRGSDMVMKVSALLSTQSSSEA 48

Query: 963 RIEYQFFEDKHSAIK 977
           R +  F  DKHS +K
Sbjct: 47  RHKVAFKGDKHSVVK 3
>33097
          Length = 446

 Score = 32.3 bits (72), Expect = 1.5,   Method: Composition-based stats.
 Identities = 14/42 (33%), Positives = 23/42 (54%)
 Frame = -1

Query: 1279 LKNTKTPVKFWFLKNYLSPTFKEFIPYMAKKYNFQYELVQYK 1320
            L+  + P+ FW LK Y   T    +P+  KKY + Y  ++Y+
Sbjct: 380  LREVEKPLLFWSLKYYFXKTHVNLLPFFKKKYIY-YHKIRYR 258
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|71043944|ref|NP_062701.2| sorting nexin 1 [Mus
musculus]
         (521 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

21098                                                                 184   8e-47
01954                                                                  54   1e-07
12345                                                                  50   3e-06
01097                                                                  44   1e-04
>21098
          Length = 518

 Score =  184 bits (467), Expect = 8e-47,   Method: Compositional matrix adjust.
 Identities = 87/165 (52%), Positives = 128/165 (77%)
 Frame = +2

Query: 357 EDNTALSRALSQLAEVEEKIEQLHQEQANNDFFLLAELLSDYIRLLAIVRAAFDQRMKTW 416
           E++T LSRALSQLAE EEKIE +H+ QA+ DF+ +AELL DYI L+  V+  F +R+K++
Sbjct: 8   EEHTTLSRALSQLAETEEKIEGIHKVQADTDFYTMAELLKDYIALIGAVKEVFHERVKSY 187

Query: 417 QRWQDAQATLQKKRESEARLLWANKPDKLQQAKDEITEWESRVTQYERDFERISTVVRKE 476
           + W++A+  L KKRE++A+    NK DK+ QAK EITEWE ++ + +++F+++S V+R+E
Sbjct: 188 KNWKEAEVMLGKKREAKAKFEVLNKTDKVSQAKQEITEWEGKMEKGQQEFDKLSKVIRRE 367

Query: 477 VTRFEKEKSKDFKNHVMKYLETLLHSQQQLAKYWEAFLPEAKAIS 521
           V RFE  + +DFK  V+KYL+TL+ +QQ+L KYWE+FL EAKAI+
Sbjct: 368 VVRFEAYRVEDFKKSVIKYLQTLMENQQKLIKYWESFLLEAKAIA 502
>01954
          Length = 1966

 Score = 54.3 bits (129), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 39/120 (32%), Positives = 67/120 (55%)
 Frame = -3

Query: 146  VGITDPEKIGDGMNAYVAYKVTTQTSLPMFRSRQFAVKRRFSDFLGLYEKLSEKHSQNGF 205
            + I DP+  G     Y  Y+V  +++LP+F+ R  +V+RR+SDF  L  +L E+ S+   
Sbjct: 1856 IDIVDPQTHGVAKARYTDYEVRMKSNLPVFKLRDSSVRRRYSDFEWLRSEL-ERDSK--I 1686

Query: 206  IVPPPPEKSLIGMTKVKVGKEDSSSAEFLEKRRAALERYLQRIVNHPTMLQDPDVREFLE 265
            +VPP P K+L      + G +     EF+E+RR  LE+++ ++  HP    +  +  FL+
Sbjct: 1685 VVPPLPGKALKRQLPFR-GDDGIFEEEFIEERRKGLEQFINKVAGHPLAQNEKCLHMFLQ 1509
>12345
          Length = 933

 Score = 49.7 bits (117), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 35/114 (30%), Positives = 61/114 (53%)
 Frame = +3

Query: 151 PEKIGDGMNAYVAYKVTTQTSLPMFRSRQFAVKRRFSDFLGLYEKLSEKHSQNGFIVPPP 210
           PEK G  +  +V Y+VT+Q     F++    V RR++DF+ LYE +  +      I+P  
Sbjct: 225 PEKKGLILK-HVEYEVTSQR----FKT---TVLRRYNDFVALYEMVMMRFPYR--ILPKL 374

Query: 211 PEKSLIGMTKVKVGKEDSSSAEFLEKRRAALERYLQRIVNHPTMLQDPDVREFL 264
           P K ++G  +           EF+E+R+ +L+R++  I  HP + +D  ++ FL
Sbjct: 375 PPKKMLGANR-----------EFIEQRKKSLKRFINIIARHPQINEDKLLKFFL 503
>01097
          Length = 2021

 Score = 44.3 bits (103), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 32/111 (28%), Positives = 56/111 (50%), Gaps = 8/111 (7%)
 Frame = +1

Query: 178 RQFAVKRRFSDFLGLYEKLSEKHSQNGFIVPPPPE------KSLIGMTKVKVGKE-DSSS 230
           R   V R+F D   L+ +L  ++   G I+PP P       KS+   TK ++G + +   
Sbjct: 268 RGMVVTRQFEDLEWLHHRLMAENDTVGIIIPPLPARPEFDPKSVESKTKKQLGSDCNILR 447

Query: 231 AEFLEKRRAALERYLQRIVNHPTMLQDPDVREFL-EKEELPRAVGTQALSG 280
            +  +    A+++YL  +++HPT  +D ++  FL EKE   R   ++ L G
Sbjct: 448 PDDFDLECKAVQKYLSLMLSHPTFGRDKNLETFLSEKEAAVRTKVSKGLIG 600
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|22164794|ref|NP_671495.1| vacuolar protein sorting 39
isoform 1 [Mus musculus]
         (886 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

19067                                                                 185   9e-47
26289                                                                 150   3e-36
25513                                                                  89   7e-18
>19067
          Length = 567

 Score =  185 bits (469), Expect = 9e-47,   Method: Compositional matrix adjust.
 Identities = 90/179 (50%), Positives = 123/179 (68%)
 Frame = -2

Query: 699 MGKHEQALFIYVHVLKDTKMAKEYCHKHYDQNKEGNKDVYLSLLRMYLSPPSIHCLGPIK 758
           +G+HEQAL IY+H+L DT +A++YC  HYD +KE +KDVYL LL+MYL PP +  LG   
Sbjct: 563 LGRHEQALAIYIHLLNDTALAEKYCEIHYDADKEESKDVYLYLLKMYLHPPDMSLLGMAP 384

Query: 759 LELLEPQANLQAALQVLELHYSKLDTTKAINLLPANTQINDIRIFLEKVLEENAQKKRFN 818
            E    + N  AAL++LE H  K+D  KA+ +LP+  ++ DI  FLE VLE NA + R N
Sbjct: 383 GEHDSSKTNTNAALKLLEDHAHKIDVPKALEMLPSTIRVRDILTFLENVLENNAAEXRHN 204

Query: 819 QVLKNLLHAEFLRVQEERILHQQVKCIITEEKVCMVCKKKIGNSAFARYPNGVVVHYFC 877
           QVLK+L  AE L V EERI +Q+++  +TE+ +C  CKK+IG+SAF   P+G + HY C
Sbjct: 203 QVLKSLTFAENLAVTEERIQYQKIRVDVTEDTLCPTCKKRIGDSAFCYTPDGSIYHYSC 27
>26289
          Length = 476

 Score =  150 bits (378), Expect = 3e-36,   Method: Compositional matrix adjust.
 Identities = 74/125 (59%), Positives = 95/125 (76%)
 Frame = +1

Query: 518 ALQVLVDQSKKANSPLKGHERTVQYLQHLGTENLHLIFSYSVWVLRDFPEDGLKIFTEDL 577
           AL +L+ Q+ + +SPLKGHERTVQYLQHLG E+L LIF Y+ WVL+  PEDGLKIFTED 
Sbjct: 1   ALSLLMKQAVRPDSPLKGHERTVQYLQHLGNEHLDLIFEYAEWVLKKHPEDGLKIFTEDT 180

Query: 578 PEVESLPRDRVLNFLIENFKALAIPYLEHIIHVWEETGSQFHNCLIQLYCEKVQSLMKDY 637
           PE+E+LPRD+VL++L +   ALAIPYLEHI+    +  ++FHN L+ L  + VQ+ M  Y
Sbjct: 181 PEIETLPRDQVLDYLEKIKPALAIPYLEHIVMDCGDETAEFHNRLVLLLKDSVQNPMDSY 360

Query: 638 LLSLP 642
           L SLP
Sbjct: 361 LNSLP 375
>25513
          Length = 1246

 Score = 89.4 bits (220), Expect = 7e-18,   Method: Compositional matrix adjust.
 Identities = 58/183 (31%), Positives = 93/183 (50%), Gaps = 2/183 (1%)
 Frame = -3

Query: 699  MGKHEQALFIYVHVLKDTKMAKEYCHKHYDQNKEG--NKDVYLSLLRMYLSPPSIHCLGP 756
            + +H++AL I VH LKD   A+ YC  +  QNK+    K ++  LL +YL P        
Sbjct: 1007 LEEHDKALRILVHKLKDFGAAENYCLVNX-QNKDPAYRKRLFHILLSVYLDP-----XYE 846

Query: 757  IKLELLEPQANLQAALQVLELHYSKLDTTKAINLLPANTQINDIRIFLEKVLEENAQKKR 816
             +  L+ P      A+ +L    ++ DT K + LLP N  +  +  FL + +  +    R
Sbjct: 845  KRDSLITP------AVALLNSSVAEFDTIKVLQLLPDNWSVGLLSQFLTRAVRSSMHDSR 684

Query: 817  FNQVLKNLLHAEFLRVQEERILHQQVKCIITEEKVCMVCKKKIGNSAFARYPNGVVVHYF 876
              ++ + +   E LR +E RI  Q+   ++ EE++C VCK+   +  F  YPNGVV H  
Sbjct: 683  MTRIERMMSRVENLRCKETRIELQREPVVMNEERLCAVCKRAFNDPTFVXYPNGVVTHVH 504

Query: 877  CSK 879
            C+K
Sbjct: 503  CAK 495
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|133504495|ref|NP_033936.2|
calcium/calmodulin-dependent serine protein kinase [Mus musculus]
         (897 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

13641                                                                 184   1e-46
15910                                                                 156   4e-38
12721                                                                 114   3e-25
01392                                                                 110   3e-24
01707                                                                 103   4e-22
35802                                                                 102   5e-22
27435                                                                 101   1e-21
21079                                                                  90   2e-21
01060                                                                 100   2e-21
14420                                                                  92   7e-19
18921                                                                  92   9e-19
13592                                                                  91   2e-18
29974                                                                  90   3e-18
00300                                                                  90   4e-18
30755                                                                  87   2e-17
14126                                                                  87   2e-17
03240                                                                  85   1e-16
17975                                                                  85   1e-16
18484                                                                  83   4e-16
11512                                                                  82   1e-15
31885                                                                  76   5e-14
29636                                                                  76   5e-14
13212                                                                  75   1e-13
01756                                                                  73   5e-13
11574                                                                  73   6e-13
01966                                                                  73   7e-13
01718                                                                  70   3e-12
08480                                                                  67   3e-11
20152                                                                  66   6e-11
26711                                                                  66   6e-11
06405                                                                  65   1e-10
00486                                                                  64   2e-10
09007                                                                  64   2e-10
13066                                                                  64   4e-10
04591                                                                  63   6e-10
28638                                                                  49   6e-10
29590                                                                  50   7e-10
09606                                                                  62   7e-10
00392                                                                  62   9e-10
29581                                                                  62   1e-09
19761                                                                  60   3e-09
19094                                                                  60   3e-09
12786                                                                  59   6e-09
38560                                                                  58   2e-08
18663                                                                  58   2e-08
03508                                                                  56   8e-08
27405                                                                  55   1e-07
04852                                                                  54   3e-07
21808                                                                  53   6e-07
26560                                                                  52   9e-07
33158                                                                  52   1e-06
37412                                                                  52   1e-06
36002                                                                  52   2e-06
21433                                                                  52   2e-06
27274                                                                  51   3e-06
04138                                                                  50   5e-06
31120                                                                  50   6e-06
27546                                                                  49   1e-05
20559                                                                  36   4e-05
01106                                                                  46   6e-05
02638                                                                  46   8e-05
32957                                                                  46   8e-05
21418                                                                  45   1e-04
32000                                                                  45   2e-04
17722                                                                  45   2e-04
12672                                                                  44   2e-04
36481                                                                  44   2e-04
20655                                                                  44   3e-04
00715                                                                  42   0.001
18401                                                                  41   0.002
14116                                                                  41   0.002
11185                                                                  40   0.004
07940                                                                  40   0.006
18287                                                                  39   0.011
07291                                                                  39   0.011
19301                                                                  39   0.011
21800                                                                  39   0.011
11404                                                                  38   0.016
20073                                                                  38   0.020
25019                                                                  37   0.047
16350                                                                  36   0.054
00638                                                                  36   0.063
26154                                                                  36   0.065
20513                                                                  36   0.071
07833                                                                  35   0.092
26009                                                                  35   0.095
31489                                                                  35   0.12 
17286                                                                  35   0.13 
22005                                                                  35   0.15 
28157                                                                  35   0.15 
23319                                                                  35   0.17 
17253                                                                  34   0.21 
30740                                                                  34   0.23 
37063                                                                  34   0.25 
13664                                                                  34   0.25 
14104                                                                  34   0.30 
32405                                                                  33   0.40 
35032                                                                  33   0.44 
18996                                                                  33   0.53 
22098                                                                  33   0.64 
17516                                                                  33   0.64 
00341                                                                  32   1.4  
20640                                                                  32   1.4  
20160                                                                  32   1.5  
16716                                                                  31   2.3  
20773                                                                  31   2.4  
12762                                                                  31   2.4  
15549                                                                  30   3.2  
17644                                                                  30   4.1  
20131                                                                  30   4.4  
03294                                                                  29   6.7  
26032                                                                  29   6.8  
17300                                                                  29   7.3  
33586                                                                  29   7.6  
>13641
          Length = 2081

 Score =  184 bits (468), Expect = 1e-46,   Method: Compositional matrix adjust.
 Identities = 117/355 (32%), Positives = 176/355 (49%), Gaps = 32/355 (9%)
 Frame = +2

Query: 555 GSITFKIVPSYRTQSSSCEDLPSTTQPKGRQIYVRAQFEYDPAKDDLIPCKEAGIRFRVG 614
           GS+T K+VPS RT  S           K R++ V+A F ++   DD IPCKEAG+ F+ G
Sbjct: 92  GSLTLKLVPSRRTPGS-----------KKREMVVKAMFSFNSKLDDNIPCKEAGLSFQQG 238

Query: 615 DIIQIISKDDHNWWQGKLENSKNGTAGLIPSPELQEWRVACIAMEKTKQEQQAS-----C 669
           DI+ I++++D  WWQ          AGLIPS    E R   +   K+K+ +  +     C
Sbjct: 239 DILHIVNQEDAIWWQAYKHGDAKKRAGLIPSRHYHE-RQEVLRKSKSKEGRHMARSISPC 415

Query: 670 TWFGXXXXXXXXXXXXXH---NAV---FDQLDLVTYEEVVKLPAFKR--KTLVLLGAHGV 721
            +               H   N     FD  ++  Y+EV       R  + +VL+GA G+
Sbjct: 416 RYSPKVPKQRRLRKTMYHIVQNGALTDFDTDEIPAYDEVEHFTPKPRHFRPIVLIGAPGI 595

Query: 722 GRRHIKNTLITKHPDRFAYPIPHTTRPPKKDEENGKNYYFVSHDQMMQDISNNEYLEYGS 781
           GR  +K  L   +P  F   +P+TTR  K  EE+GK Y+FVS + M + I   +++EYG 
Sbjct: 596 GRNELKRRLKASNPMHFLEVVPYTTRTKKPFEEDGKEYHFVSREDMEESIIAQKFVEYGE 775

Query: 782 HEDAMYGTKLETIRKIHEQGLIAILDVEPQALKVLRTAEFAPFVVFIAAPTITPGLNED- 840
           H   +YGT +E+I+++   G + +L    QALK LRT E  P+V+FI +PT+   L E  
Sbjct: 776 HHGHLYGTSVESIKQVIAAGKVCLLTPHTQALKFLRTYELKPYVIFIKSPTLE-KLKESR 952

Query: 841 ------------------ESLQRLQKESDVLQRTYAHYFDLTIINNEIDETIRHL 877
                             E L+ + + S  L+  Y H FD+TI+N+ + +    L
Sbjct: 953 MPARARATEADSIRPFSIEELEEMAETSRRLEERYGHVFDITIVNDSLTDATTEL 1117
>15910
          Length = 1361

 Score =  156 bits (394), Expect = 4e-38,   Method: Compositional matrix adjust.
 Identities = 84/215 (39%), Positives = 128/215 (59%), Gaps = 7/215 (3%)
 Frame = +2

Query: 113 YSEAVASHYMRQILEALRYCHDNNIIHRDVKPHCVLLASKENSAPVKLGGFGVAIQLGES 172
           Y+E  A+  +  IL  ++Y H N ++HRD+KP  +L     + + +KL  FG++ ++ E 
Sbjct: 455 YTEKDAARAISDILHGVQYIHANGVVHRDLKPENLLYECMTDDSKLKLADFGLS-RIIEP 631

Query: 173 GLVAGGRVGTPHFMAPEVVKREPYGKPVDVWGCGVILFILLSGCLPFYGTKE-RLFEGII 231
            +      GTP + APEV+K + Y   VD+W  GVI +ILL G  PF+   E  ++  II
Sbjct: 632 EVQMSTVCGTPGYCAPEVLKGDKYTPSVDMWSVGVIAYILLCGYEPFFAENEFEMYRKII 811

Query: 232 KGKYKMNPRQWSHISESAKDLVRRMLMLDPAERITVYEALNHPWLKERDRYAYKIHLPET 291
           KG+YK +   WS ISE+AKD+VR++L++DP +R+T  EAL  PW+K        + +  T
Sbjct: 812 KGEYKFDEEYWSEISENAKDVVRKLLVIDPKKRLTATEALRLPWVKGVATKTTNMEI--T 985

Query: 292 VEQLRKFNARRKLKGA------VLAAVSSHKFNSF 320
           + +L++FNARRKLK A      +  A +   FNSF
Sbjct: 986 MNKLKEFNARRKLKCATDAMLVIAKATTDIPFNSF 1090
>12721
          Length = 821

 Score =  114 bits (284), Expect = 3e-25,   Method: Compositional matrix adjust.
 Identities = 81/249 (32%), Positives = 121/249 (48%)
 Frame = +1

Query: 18  IGKGPFSVVRRCINRETGQQFAVKIVDVAKFTSSPGLSTEDLKREASICHMLKHPHIVEL 77
           IG+G   +V    +R+ G+Q AVK +D+ K         E L  E  +     HP+IVE+
Sbjct: 112 IGEGSTGIVCIATSRD-GRQMAVKKMDLRKQQRR-----ELLFNEVVVMRDYHHPNIVEM 273

Query: 78  LETYSSDGMLYMVFEFMDGADLCFEIVKRADAGFVYSEAVASHYMRQILEALRYCHDNNI 137
             +Y  +  L++V EFM+G  L  +IV       V    V     R  L+AL + H N +
Sbjct: 274 YNSYLVNDELWVVMEFMEGGALT-DIVTNNRMDEVQIATVC----RACLKALAFLHANGV 438

Query: 138 IHRDVKPHCVLLASKENSAPVKLGGFGVAIQLGESGLVAGGRVGTPHFMAPEVVKREPYG 197
           IHRD+K   +LL+   +   VKL  FG   Q+ +        VGTP++MAPEV+ R PYG
Sbjct: 439 IHRDIKSDSILLS---HDGKVKLXDFGFCAQVTQDLQKRKSLVGTPYWMAPEVISRLPYG 609

Query: 198 KPVDVWGCGVILFILLSGCLPFYGTKERLFEGIIKGKYKMNPRQWSHISESAKDLVRRML 257
             VD+W  G+++  ++    PF+          I+       R    IS   +  + RML
Sbjct: 610 PEVDIWSLGIMVMEMIDAEPPFFNEPPLQAMRRIRDMPPPKLRNTHKISPRLQGFIDRML 789

Query: 258 MLDPAERIT 266
           + DP +R T
Sbjct: 790 VRDPHQRAT 816
>01392
          Length = 1806

 Score =  110 bits (274), Expect = 3e-24,   Method: Compositional matrix adjust.
 Identities = 67/193 (34%), Positives = 95/193 (49%), Gaps = 31/193 (16%)
 Frame = -1

Query: 115  EAVASHYMRQILEALRYCHDNNIIHRDVKPHCVLLASKENSAPVKLGGFGVAIQLGESGL 174
            E  AS  +R I  AL + H   I HRD+KP  +L    ++  PVK+  F +A     SG+
Sbjct: 1794 EREASLVVRHIARALDFLHSKGIAHRDLKPENILCEHLDDVVPVKICDFDLA-----SGI 1630

Query: 175  VAGGR----------VGTPHFMAPEVVKRE-----PYGKPVDVWGCGVILFILLSGCLPF 219
               G           VG+  +MAPEVV         Y K  D+W  G+IL+I+L G  PF
Sbjct: 1629 SCDGDGTKTPELLTPVGSAEYMAPEVVDAWVGDSFSYDKRCDLWSLGIILYIMLCGYPPF 1450

Query: 220  YG----------------TKERLFEGIIKGKYKMNPRQWSHISESAKDLVRRMLMLDPAE 263
            YG                 ++ LF  I  G YK   ++W+ IS SAKDL+R +L+ +P +
Sbjct: 1449 YGQCGEDCGWNRGEACHDCQDMLFNSIQDGHYKFPSQEWTSISSSAKDLIRHLLVREPRK 1270

Query: 264  RITVYEALNHPWL 276
            R +  + L HPW+
Sbjct: 1269 RYSAADVLKHPWI 1231
>01707
          Length = 757

 Score =  103 bits (256), Expect = 4e-22,   Method: Compositional matrix adjust.
 Identities = 74/207 (35%), Positives = 102/207 (49%), Gaps = 3/207 (1%)
 Frame = +1

Query: 12  YELCEVIGKGPFSVVRRCINRETGQQFAVKIVDVAKFTSSPG--LSTEDLKREASICHML 69
           YE    IG+G + VV +C N+ET Q  A+K     KF  S    L  +   RE  +   L
Sbjct: 70  YEKIGKIGEGSYGVVFKCRNKETSQLVAIK-----KFVESEDDPLIKKIAMREIRMLKQL 234

Query: 70  KHPHIVELLETYSSDGMLYMVFEFMDGADLCFEIVKRADAGFVYSEAVASHYMRQILEAL 129
           KHP++V L+E +     L++VF+++D   L    + R   G    E +    + Q L A+
Sbjct: 235 KHPNLVRLIEVFRRKKRLHLVFDYVDHTLL--NELDRYPRGL--PEPMVKRIIYQTLLAV 402

Query: 130 RYCHDNNIIHRDVKPHCVLLASKENSAPVKLGGFGVAIQLGESGLVAGGRVGTPHFMAPE 189
            +CH  N IHRDVKP  +L+  +     VKL  FG A  L   G      V T  + APE
Sbjct: 403 NFCHQYNTIHRDVKPENILITRQ---GQVKLCDFGFARILTGPGDEYTDYVATRWYRAPE 573

Query: 190 -VVKREPYGKPVDVWGCGVILFILLSG 215
            +V    YG PVDVW  G +   LL+G
Sbjct: 574 LLVGDTQYGPPVDVWAIGCVFAELLTG 654
>35802
          Length = 571

 Score =  102 bits (255), Expect = 5e-22,   Method: Compositional matrix adjust.
 Identities = 45/157 (28%), Positives = 86/157 (54%), Gaps = 13/157 (8%)
 Frame = +1

Query: 753 EENGKNYYFVSHDQMMQDISNNEYLEYGSHEDAMYGTKLETIRKIHEQGLIAILDVEPQA 812
           E  G++Y+F S      D+ + ++LEYG  +  +YGT +E +R++  QG + +L++EP++
Sbjct: 1   EMTGRDYHFTSRSMFEADMLSGKFLEYGEFQSNLYGTSVEAVRQVILQGRVCLLNLEPES 180

Query: 813 LKVLRTAEFAPFVVFIAAPT-------------ITPGLNEDESLQRLQKESDVLQRTYAH 859
           LK+LR  +  P+  F+  P              I P    D+ L+ +  +   ++  Y H
Sbjct: 181 LKILRETDLKPYTXFVCPPNMEKLRQLHIAMGKIRPT---DDQLKTVMDKGREMEDMYGH 351

Query: 860 YFDLTIINNEIDETIRHLEEAVELVCTAPQWVPVSWV 896
           +FD  ++N ++D +++ L   +  +   PQWVPV+W+
Sbjct: 352 FFDYKLVNMDVDRSVQELMAEINRIEVEPQWVPVTWM 462
>27435
          Length = 456

 Score =  101 bits (251), Expect = 1e-21,   Method: Compositional matrix adjust.
 Identities = 46/153 (30%), Positives = 90/153 (58%), Gaps = 11/153 (7%)
 Frame = +1

Query: 753 EENGKNYYFVSHDQMMQDISNNEYLEYGSHEDAMYGTKLETIRKIHEQGLIAILDVEPQA 812
           E NGK+Y+F++      D+ + +++EYG  +  +YGT +E +R++ +QG I IL++ P++
Sbjct: 1   EHNGKDYHFITRAVFEADMLSGKFVEYGEFQGNLYGTTVEAVRQVIQQGRICILNLGPES 180

Query: 813 LKVLRTAEFAPFVVFIAAPTI-----------TPGLNEDESLQRLQKESDVLQRTYAHYF 861
           LK LR  E  P+++FI+ P +            P   +D+  + +++  + ++  Y+HYF
Sbjct: 181 LKNLRETELKPYIIFISPPXMEKLRQLQMALGKPRPTDDQVKEVIERGRE-MEEMYSHYF 357

Query: 862 DLTIINNEIDETIRHLEEAVELVCTAPQWVPVS 894
           D  ++N E++     L + +  + T PQWVP++
Sbjct: 358 DYILVNMELNRAFDELLQEINRIETEPQWVPIT 456
>21079
          Length = 878

 Score = 89.7 bits (221), Expect(2) = 2e-21,   Method: Compositional matrix adjust.
 Identities = 56/148 (37%), Positives = 82/148 (55%)
 Frame = +1

Query: 71  HPHIVELLETYSSDGMLYMVFEFMDGADLCFEIVKRADAGFVYSEAVASHYMRQILEALR 130
           HP ++ L + + +   + +V EF+   +L FE V R D  FV +E    H++RQI   + 
Sbjct: 1   HPKLLMLWDAFEAPRTMVLVMEFVGAGEL-FERVIRDD--FVLTERDCVHFVRQICSGVG 171

Query: 131 YCHDNNIIHRDVKPHCVLLASKENSAPVKLGGFGVAIQLGESGLVAGGRVGTPHFMAPEV 190
           Y H  +I+H D+KP  VL  S +NS  +K+  FG+A +  + G       GTP F+APEV
Sbjct: 172 YMHTQSILHLDLKPENVLCVS-DNSNQIKIIDFGLA-RFYKPGDSLQVLFGTPEFIAPEV 345

Query: 191 VKREPYGKPVDVWGCGVILFILLSGCLP 218
           V  +      D+W  GVI +ILLSG  P
Sbjct: 346 VNYDEINFTTDMWSIGVICYILLSGLSP 429

 Score = 32.0 bits (71), Expect(2) = 2e-21,   Method: Composition-based stats.
 Identities = 19/58 (32%), Positives = 31/58 (53%)
 Frame = +2

Query: 246 SESAKDLVRRMLMLDPAERITVYEALNHPWLKERDRYAYKIHLPETVEQLRKFNARRK 303
           S++AKD +      +  +R+T+ +   H WL E+D+      L    ++LR F ARRK
Sbjct: 512 SDNAKDFIGNC*SREKEKRMTIEQCDKHSWLAEQDQRIRCKRL--NTDRLRCFMARRK 679
>01060
          Length = 1800

 Score =  100 bits (249), Expect = 2e-21,   Method: Compositional matrix adjust.
 Identities = 87/316 (27%), Positives = 142/316 (44%), Gaps = 27/316 (8%)
 Frame = +1

Query: 1   MADDDVLFEDVYELCEVIGKGPFSVVRRCINRETGQQFAVKIVDVAKFTSSPGLSTEDLK 60
           M D +    D+ +  + IG+G + VV +C +R TG++ A+K + +    S  G+ +  + 
Sbjct: 49  MMDFETALSDLTDF-QKIGEGTYGVVYKCRHRATGRKLAMKKIRLRG--SEDGVPSSAI- 216

Query: 61  REASICHMLKHPHIVELLETYSSDGMLYMVFEFMDGADLCFEIVKRADAGFVYSEAVASH 120
           RE ++   L+H +IV L +    D  L++VFEF+   DL   I K  + G V    +   
Sbjct: 217 REIAMLRELRHTNIVCLEDVIMEDERLFLVFEFL-SMDLKMYIDKFPE-GVVLDRRLVKS 390

Query: 121 YMRQILEALRYCHDNNIIHRDVKPHCVLLASKENSAPVKLGGFGVAIQLGESGLVAGGRV 180
           Y+ QI+  + +CH   I+HRD+KP  +L+    ++  +K+  FG+A             V
Sbjct: 391 YVFQIVTGIXFCHQRRIVHRDLKPQNLLI---NHTGAIKIADFGMARTFALPVRAYTHEV 561

Query: 181 GTPHFMAPEVVK-REPYGKPVDVWGCGVILFILLSGCLPFYGTKE-----RLFEGIIKGK 234
            T  + APE++     Y  PVDVW  G I   +L     F G  E     ++F  I    
Sbjct: 562 VTLWYRAPEILMGASKYSTPVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIFRIIGTPT 741

Query: 235 YKMNPR------------QW--SHISES-------AKDLVRRMLMLDPAERITVYEALNH 273
            +  P              W    +SE+         DL+ R L  DPA+RI+  + L H
Sbjct: 742 EQTWPEFHKLPAFNGMFPLWKEGKLSETLTDLDSLGLDLIERTLKCDPAQRISCKKMLQH 921

Query: 274 PWLKERDRYAYKIHLP 289
            +    D     + +P
Sbjct: 922 AYFLNVDTSVKPVDVP 969
>14420
          Length = 528

 Score = 92.4 bits (228), Expect = 7e-19,   Method: Compositional matrix adjust.
 Identities = 52/150 (34%), Positives = 78/150 (52%)
 Frame = +2

Query: 70  KHPHIVELLETYSSDGMLYMVFEFMDGADLCFEIVKRADAGFVYSEAVASHYMRQILEAL 129
           ++P+IV  L++Y     L++V EF+ G  L   + +         E   +   R+ L+AL
Sbjct: 74  QNPNIVNYLDSYLVGEELWVVMEFLAGGSLTDVVTETC-----MDEGQIAAVCRECLQAL 238

Query: 130 RYCHDNNIIHRDVKPHCVLLASKENSAPVKLGGFGVAIQLGESGLVAGGRVGTPHFMAPE 189
            + H+N +IHRD+K   +LL        VKL  FG   QL          VGTP++MAPE
Sbjct: 239 EFLHENQVIHRDIKSDNILLGM---DGSVKLTDFGFCAQLSPEQSKRSTMVGTPYWMAPE 409

Query: 190 VVKREPYGKPVDVWGCGVILFILLSGCLPF 219
           VV R+ YG  VD+W  GV+   ++ G  P+
Sbjct: 410 VVTRKQYGPTVDIWSLGVMCIEMIEGEPPY 499
>18921
          Length = 697

 Score = 92.0 bits (227), Expect = 9e-19,   Method: Compositional matrix adjust.
 Identities = 64/214 (29%), Positives = 103/214 (48%)
 Frame = +2

Query: 9   EDVYELCEVIGKGPFSVVRRCINRETGQQFAVKIVDVAKFTSSPGLSTEDLKREASICHM 68
           EDV+++   +G+G +  V + +++ETGQ  A+K V V           +++ +E SI   
Sbjct: 26  EDVFDILGKLGEGSYGSVFKSLHKETGQVLAIKQVPVDT-------DLQEIIKEISIMQQ 184

Query: 69  LKHPHIVELLETYSSDGMLYMVFEFMDGADLCFEIVKRADAGFVYSEAVASHYMRQILEA 128
               +IV+   +Y  +  L++V E+  GA    +I++  +   V  E     Y    L+ 
Sbjct: 185 CDSKYIVKYYGSYFKNTDLWIVMEYC-GAGSVSDIMRLRNKTLVEREIATILYYT--LKG 355

Query: 129 LRYCHDNNIIHRDVKPHCVLLASKENSAPVKLGGFGVAIQLGESGLVAGGRVGTPHFMAP 188
           L Y H    IHRD+K   +LL    N    KL  FGVA QL ++       +GTP++MAP
Sbjct: 356 LXYLHSRRKIHRDIKAGNILL---NNEGHAKLADFGVAGQLTDTMAKRNTVIGTPYWMAP 526

Query: 189 EVVKREPYGKPVDVWGCGVILFILLSGCLPFYGT 222
           EV++   Y    D+W  G+    +  G  P   T
Sbjct: 527 EVIQEIGYDCVADIWSLGITALEMAEGKPPVMET 628
>13592
          Length = 980

 Score = 90.9 bits (224), Expect = 2e-18,   Method: Compositional matrix adjust.
 Identities = 72/274 (26%), Positives = 127/274 (46%), Gaps = 14/274 (5%)
 Frame = +2

Query: 18  IGKGPFSVVRRCINRETGQQFAVKIVDVAKFTSSPG--LSTEDLKREASICHMLKHPHIV 75
           IG+G F  V   +N  TG+  A+K + +      PG   + +++  E  I   +KH ++V
Sbjct: 8   IGQGRFGKVYTAVNNNTGELMAMKEIAI-----QPGETRALKNVAEELKILEGIKHKNLV 172

Query: 76  EL--LETYSSDGMLYMVFEFMDGADLC----FEIVKRADAGFVYSEAVASHYMRQILEAL 129
               +E +  + +++M        +LC     E +     G    EA++  +  Q+L  +
Sbjct: 173 RYYGIEVHREELLIFM--------ELCSEGTLESLVELTGGL--PEALSRRFTAQLLSGV 322

Query: 130 RYCHDNNIIHRDVKPHCVLLASKENSAPVKLGGFGVAIQLGESGLVAG---GRVGTPHFM 186
              H + I+HRD+K   + L    NS  +KLG FG A+++     V G   G VGT  +M
Sbjct: 323 AELHKHGIVHRDIKTANIFLVDGSNS--LKLGDFGSAVKIQAHTTVPGELQGYVGTQAYM 496

Query: 187 APEVVKR---EPYGKPVDVWGCGVILFILLSGCLPFYGTKERLFEGIIKGKYKMNPRQWS 243
           APEV  +   + +G+  D+W  G ++  + SG  P +   +  F+ + K      P+   
Sbjct: 497 APEVFTKTNSDGHGRLADIWSVGCVVVEMASGKRP-WAQFDSNFQIMFKVGMGEKPQAPE 673

Query: 244 HISESAKDLVRRMLMLDPAERITVYEALNHPWLK 277
            +S+   D +   L  DP +R++  E L   + K
Sbjct: 674 SLSQEGHDFIDHCLQHDPKQRLSAIELLEQNFCK 775
>29974
          Length = 344

 Score = 90.1 bits (222), Expect = 3e-18,   Method: Compositional matrix adjust.
 Identities = 43/103 (41%), Positives = 68/103 (66%), Gaps = 1/103 (0%)
 Frame = +1

Query: 727 KNTLITKHPDRFAYPIPHTTRPPKKDEENGKNYYFVS-HDQMMQDISNNEYLEYGSHEDA 785
            + LI++ PD+F   IPHTTR  + +EE G++Y+FVS  +QM +DI N+ ++E G + D 
Sbjct: 1   NDDLISEFPDKFGSCIPHTTRERRTNEEPGQDYHFVSSREQMERDIQNHLFIEAGVYNDN 180

Query: 786 MYGTKLETIRKIHEQGLIAILDVEPQALKVLRTAEFAPFVVFI 828
           +YGT + +++++ EQG   ILDV   A+K L+ A   P  +FI
Sbjct: 181 LYGTSVASVKEVAEQGRHCILDVSGNAIKRLQVAGLYPIAIFI 309
>00300
          Length = 2318

 Score = 90.1 bits (222), Expect = 4e-18,   Method: Compositional matrix adjust.
 Identities = 70/266 (26%), Positives = 122/266 (45%), Gaps = 6/266 (2%)
 Frame = -1

Query: 18   IGKGPFSVVRRCINRETGQQFAVKIVDVAKFTSSPGLSTEDLKREASICHMLKHPHIVEL 77
            IG+G F  V   +N  TG+  A+K +   KF  +      ++  E  I   ++H ++V+ 
Sbjct: 1634 IGEGQFGKVYTAVNMSTGELMALKEM---KFQPNDLQQLREMCDEIKIFEGIQHENLVKY 1464

Query: 78   LETYSSDGMLYMVFEFMDGADLCFEIVKRADAGFVYSEAVASHYMRQILEALRYCHDNNI 137
                     + M  E+ D       I + A  G    E +   Y R+I+ A+ + H+N+I
Sbjct: 1463 YGVEVHKDEMLMFMEYCDTGT----IEEAAKMGL--PEYLIRRYTREIVLAVNHLHENSI 1302

Query: 138  IHRDVKPHCVLLASKENSAPVKLGGFGVAIQLGESGLVAG---GRVGTPHFMAPEVVKRE 194
            +HRD+K   + L S   +  VKLG FG +++L     + G     VGT  +MAPEV  + 
Sbjct: 1301 VHRDIKGANIFLTS---NGHVKLGDFGCSVKLKSHTTMPGEFHNLVGTTAYMAPEVFTQN 1131

Query: 195  P---YGKPVDVWGCGVILFILLSGCLPFYGTKERLFEGIIKGKYKMNPRQWSHISESAKD 251
                YG+  D+W  G ++  + +G  P++      ++ + K      P     +S   K 
Sbjct: 1130 DQGGYGRAADIWSLGCVVIEMATGKRPWHDLDNN-YQIMYKVGIGHKPAVPDSLSVEGKH 954

Query: 252  LVRRMLMLDPAERITVYEALNHPWLK 277
             +  ++  DPA+R    + L+H + K
Sbjct: 953  FLDLIMCHDPAQRALASQLLDHTFTK 876
>30755
          Length = 1137

 Score = 87.4 bits (215), Expect = 2e-17,   Method: Compositional matrix adjust.
 Identities = 53/170 (31%), Positives = 85/170 (50%), Gaps = 5/170 (2%)
 Frame = +2

Query: 112 VYSEAVASHYMRQILEALRYCHDNNIIHRDVKPHCVLLASKENSAPVKLGGFGVAIQLGE 171
           +++E     Y  +I+ AL Y H   II+RD+K   +LL   +    +K+  FG+  +   
Sbjct: 20  IFTEERTRFYGAEIISALGYLHSQGIIYRDLKLENLLL---DKDGHIKVADFGLCKEDIT 190

Query: 172 SGLVAGGRVGTPHFMAPEVVKREPYGKPVDVWGCGVILFILLSGCLPFYGTKERLFEGII 231
            G       GTP ++APEV+    YG+ VD WG GV+++ ++ G LPFY     +   +I
Sbjct: 191 YGRTTKTFCGTPEYLAPEVLDDNDYGRAVDWWGTGVVMYEMICGRLPFYNRDHDVLFTLI 370

Query: 232 KGKYKMNPRQWSHISESAKDLVRRMLMLDPAERI-----TVYEALNHPWL 276
             +    PR   +I++ AK L+  +L  DP  R+      V E   HP+ 
Sbjct: 371 LVEDVKFPR---NITDEAKSLLSGLLAKDPRNRLGGGQDDVKEIQAHPFF 511
>14126
          Length = 1265

 Score = 87.4 bits (215), Expect = 2e-17,   Method: Compositional matrix adjust.
 Identities = 80/303 (26%), Positives = 137/303 (45%), Gaps = 33/303 (10%)
 Frame = +3

Query: 9   EDVYELCEVIGKGPFSVVRRCIN-RETGQQFAVKIVDVAKFTSSPGLSTEDLKREASICH 67
           E  YE   VIG G +  V +  + R  G+  A+K + +    +  G+    + RE S+  
Sbjct: 186 EQKYEEVAVIGNGAYGTVYKARDLRNQGEFVAMKRIRLN--NTEEGMPMMAI-REISMLK 356

Query: 68  MLK---HPHIVELLETYSS-----DGMLYMVFEFMDGADLCFEIVKRADAGFVYSEAVAS 119
            L+   HP++V LL+   +     +  L +VFE+++  DL   + K    G         
Sbjct: 357 QLEQYEHPNVVRLLDVSHNTITDREIRLNLVFEYIE-HDLATYLAKCPSPGL--GPDRIK 527

Query: 120 HYMRQILEALRYCHDNNIIHRDVKPHCVLLASKENSAPVKLGGFGVAIQLGESGLVAGGR 179
             M Q+L  + + H N I+HRD+KP  +L++       +KL  FG+A ++    +     
Sbjct: 528 DLMLQLLNGVDFLHSNRIVHRDLKPQNLLIS---KDGRLKLADFGLA-RIYSFHMALTTV 695

Query: 180 VGTPHFMAPEVVKREPYGKPVDVWGCGVILFILLSGCLPFYGTKE-----RLFE------ 228
           V T  + +PEV+ +  YG  VD+W CG I   L +    F G+ E     ++FE      
Sbjct: 696 VVTLWYRSPEVLMQAEYGTSVDIWSCGCIFAELFTRRALFKGSSEFDQLKKIFEVIGLPP 875

Query: 229 --------GIIKGKYKMNP-----RQWSHISESAKDLVRRMLMLDPAERITVYEALNHPW 275
                    + +  ++  P          +   AKDL+ +ML+     RI+  E+L HP+
Sbjct: 876 AGDWPEGVSVHRNSFRPTPPVPLQTLVPEMDPQAKDLMEKMLVFKSGRRISSRESLLHPY 1055

Query: 276 LKE 278
           L++
Sbjct: 1056LRD 1064
>03240
          Length = 1683

 Score = 85.1 bits (209), Expect = 1e-16,   Method: Compositional matrix adjust.
 Identities = 76/299 (25%), Positives = 127/299 (42%), Gaps = 46/299 (15%)
 Frame = -3

Query: 4    DDVLFEDVYELCEVIGKGPFSVVRRCINRETGQQFAVKIVDVAKFTSSPGLSTEDLKREA 63
            D  +FE +    + +G G F  V  C   +TG  +A+K +  +       ++   +K E 
Sbjct: 1297 DKCMFEKI----KTLGVGAFGEVSLCRKNDTGMLYAMKTLRKSDVLKRNQVA--HVKAER 1136

Query: 64   SICHMLKHPHIVELLETYSSDGMLYMVFEFMDGADLCFEIVKRADAGFVYSEAVASHYMR 123
             I     +  +V+L  ++     LY V +++ G DL   +++      +  E +A  Y+ 
Sbjct: 1135 DILAEADNEWVVKLYYSFQDHNYLYFVMDYVPGGDLMGLLIRME----ILDEPLARFYVA 968

Query: 124  QILEALRYCHDNNIIHRDVKPHCVLLASKENSAPVKLGGFG------------------- 164
            ++++A+   H    IHRD+KP  +L+   + +  +KL  FG                   
Sbjct: 967  ELVQAIESVHRMGFIHRDIKPDNILI---DRNGHIKLTDFGLCTGFRWTHNSKYYQRDGT 797

Query: 165  --------VAIQLGESG-----------------LVAGGRVGTPHFMAPEVVKR-EPYGK 198
                    V  QL E                    +A   VGTP+++APEV+ R   Y  
Sbjct: 796  HARQDSMEVKCQLDEQCQCEILKPLERRRKREQRCLAHSLVGTPNYIAPEVLSRLGGYTS 617

Query: 199  PVDVWGCGVILFILLSGCLPFYG-TKERLFEGIIKGKYKMNPRQWSHISESAKDLVRRM 256
              D W  GVILF +L G  PFY  T       +I  K  +   + S++S+ AKDL+ R+
Sbjct: 616  VCDWWSVGVILFEMLVGHPPFYANTPAETQYKVINWKDMLKIPRESNLSQPAKDLILRL 440
>17975
          Length = 449

 Score = 85.1 bits (209), Expect = 1e-16,   Method: Compositional matrix adjust.
 Identities = 50/150 (33%), Positives = 82/150 (54%)
 Frame = +3

Query: 23  FSVVRRCINRETGQQFAVKIVDVAKFTSSPGLSTEDLKREASICHMLKHPHIVELLETYS 82
           F+VV+   +  TG++ AVK++D  K      +S   L +E     +++HP++V L E   
Sbjct: 6   FAVVKLARHVFTGEKVAVKVIDKTKLDE---VSRSHLFQEVRCMKLVQHPNVVRLYEVID 176

Query: 83  SDGMLYMVFEFMDGADLCFEIVKRADAGFVYSEAVASHYMRQILEALRYCHDNNIIHRDV 142
           +   LY++ E  DG D+ ++ + R   G    E +A  Y RQI+EA+ YCH  +++HRD+
Sbjct: 177 TQTKLYLILELGDGGDM-YDYIMRHSGGL--EEKLAKRYFRQIVEAISYCHKLHVVHRDL 347

Query: 143 KPHCVLLASKENSAPVKLGGFGVAIQLGES 172
           KP  V+    E    VKL  FG +  L ++
Sbjct: 348 KPENVVFF--EKPGLVKLTDFGFSTCLLQA 431
>18484
          Length = 635

 Score = 83.2 bits (204), Expect = 4e-16,   Method: Compositional matrix adjust.
 Identities = 53/154 (34%), Positives = 79/154 (51%), Gaps = 1/154 (0%)
 Frame = +1

Query: 113 YSEAVASHYMRQILEALRYCHDNNIIHRDVKPHCVLLASKENSAPVKLGGFGVAIQLGES 172
           + E VA+ Y  +I   L + HD  II+RD+K   V+L S+ +   +K+  FG+  +    
Sbjct: 34  FKEPVAAFYAAEIAVGLFFLHDQGIIYRDLKLDNVMLDSEGH---IKIADFGMCKEGMTG 204

Query: 173 GLVAGGRVGTPHFMAPEVVKREPYGKPVDVWGCGVILFILLSGCLPFYGTKE-RLFEGII 231
                   GTP ++APE+V  +PY K VD W  GV+LF +L+G  PF G  E  LF  I 
Sbjct: 205 DATTRTFCGTPDYIAPEIVLYQPYSKSVDWWAYGVLLFEMLAGQPPFDGEDEDELFSSIT 384

Query: 232 KGKYKMNPRQWSHISESAKDLVRRMLMLDPAERI 265
                 N      +S  A  L + +LM +P +R+
Sbjct: 385 ----DHNVSYPKAMSREAVSLCKGLLMKNPTKRL 474
>11512
          Length = 1006

 Score = 81.6 bits (200), Expect = 1e-15,   Method: Compositional matrix adjust.
 Identities = 44/157 (28%), Positives = 76/157 (48%), Gaps = 19/157 (12%)
 Frame = -3

Query: 759  YYFVSHDQMMQDISNNEYLEYGSHEDAMYGTKLETIRKIHEQGLIAILDVEPQALKVLRT 818
            Y FV+ ++M  DI   +++E+G ++  +YGT  E+++ I   G + +L    QA+K LRT
Sbjct: 1004 YIFVAREKMDADIEAGKFVEHGEYKGHLYGTSAESVKSIVNAGCVCVLSPHYQAIKTLRT 825

Query: 819  AEFAPFVVFIAAPTI------------TPGLNE-------DESLQRLQKESDVLQRTYAH 859
             +  PF++ I  P +                +E       DE  + + K +  +  TY H
Sbjct: 824  XQLKPFLIHIKPPELDILKSTRTEARAKSTFDEANARSFTDEEFEDMIKSTXRIDFTYGH 645

Query: 860  YFDLTIINNEIDETIRHLEEAVELVCTAPQWVPVSWV 896
            +FD+ I+N E+      L + V+ +   P W P  WV
Sbjct: 644  FFDVEIVNGELLAAFEXLVQHVQRLENEPLWAPSMWV 534
>31885
          Length = 529

 Score = 76.3 bits (186), Expect = 5e-14,   Method: Compositional matrix adjust.
 Identities = 52/156 (33%), Positives = 72/156 (46%), Gaps = 5/156 (3%)
 Frame = -2

Query: 69  LKHPHIVELLETYSSDGMLYMVFEFMDGADLCFEIVKRADAGFVYSEAVASHYMRQILEA 128
           L HP +V L   +  +  L+MV +   G DL + + +       + E     Y+ Q+   
Sbjct: 501 LDHPFLVNLWYAFQDEEDLFMVVDLFLGGDLRYHMQQEVS----FREDCVKFYLCQLALV 334

Query: 129 LRYCHDNNIIHRDVKPHCVLLASKENSAPVKLGGFGVAIQLGESGLVAGGRVGTPHFMAP 188
           L Y     I+HRD+KP  +LL   +      +  F +A QL E   +A    GT  +MAP
Sbjct: 333 LDYLRSQKIVHRDIKPDNILL---DEQGHCHVTDFNIATQL-EDDELATSTSGTRPYMAP 166

Query: 189 EVV-----KREPYGKPVDVWGCGVILFILLSGCLPF 219
           EV      +R  YG PVD W  GV LF LL    PF
Sbjct: 165 EVYGVAINERRGYGFPVDWWSLGVSLFELLKKRRPF 58
>29636
          Length = 354

 Score = 76.3 bits (186), Expect = 5e-14,   Method: Compositional matrix adjust.
 Identities = 44/98 (44%), Positives = 54/98 (55%), Gaps = 1/98 (1%)
 Frame = +1

Query: 556 SITFKIVPSYRTQSSSCEDLPSTTQPKGRQIYVRAQFEYDPAKDDLIPCKEAGIRFRVGD 615
           +ITF I+P++    S  ED   TT   G  +++RA F YDP  D  IPC+E GI F  GD
Sbjct: 1   TITFMIIPAH----SCVED---TTAKPGDIMHLRALFNYDPEDDPYIPCRELGISFLKGD 159

Query: 616 IIQIISKDDHNWWQGKLEN-SKNGTAGLIPSPELQEWR 652
           I+  I   D NWWQ   E    +  AGLIPS   QE R
Sbjct: 160 ILHAIQLSDSNWWQAHREGEDAHMLAGLIPSKAFQEQR 273
>13212
          Length = 1067

 Score = 74.7 bits (182), Expect = 1e-13,   Method: Compositional matrix adjust.
 Identities = 56/175 (32%), Positives = 83/175 (47%), Gaps = 11/175 (6%)
 Frame = -1

Query: 114 SEAVASHYMRQILEALRYCHDNNIIHRDVKPHCVLLASKENSAPVKLGGFGVAIQLGESG 173
           +EA   +   ++  AL + H +++IHRD+K   VLL        VKL  FGV+ +  ++ 
Sbjct: 986 TEAQICYVCHEMCMALDFLHRHHVIHRDIKAGNVLLTI---DGEVKLADFGVSAKNTQTQ 816

Query: 174 LVAGGRVGTPHFMAPEVV-----KREPYGKPVDVWGCGVILFILLSGCLPFYGTKE---- 224
                 +GTP++MAPEVV     K  PY    D+W  GV L        P    KE    
Sbjct: 815 QKRDTFIGTPYWMAPEVVLCETLKDTPYDFKADIWSLGVTLIEFAQIEPP---NKEMHPM 645

Query: 225 RLFEGIIKGKYKM--NPRQWSHISESAKDLVRRMLMLDPAERITVYEALNHPWLK 277
           R+   I K        P++W+ +    KD + + L+ DP  R T  E L HP++K
Sbjct: 644 RVLIKIHKSDPPTLEKPKKWTKL---FKDFIAKCLVKDPNLRPTAAELLEHPFMK 489
>01756
          Length = 1858

 Score = 72.8 bits (177), Expect = 5e-13,   Method: Compositional matrix adjust.
 Identities = 79/295 (26%), Positives = 125/295 (42%), Gaps = 21/295 (7%)
 Frame = -3

Query: 12   YELCEVIGKGPFSVVRRCINRETGQQFAVKIVDVAKFTSSPGLSTEDLKREASICHMLKH 71
            YE    IG+G F  V +   ++T Q  A+K V +       G     L RE  I  +L H
Sbjct: 1736 YEKLAKIGQGTFGEVFKARCKKTKQVVAMKKVLMD--NEKEGFPITAL-REIKILQLLNH 1566

Query: 72   PHIVELLETYSSDG--------MLYMVFEFM--DGADLCFEIVKRADAGFVYSEAVASHY 121
             ++V+L+E  S+          M Y+VFEF   D A L       ++   V++       
Sbjct: 1565 ENVVDLIEICSTKATSANRYKSMFYLVFEFCEHDLAGLL------SNMSVVFNLPEIKEV 1404

Query: 122  MRQILEALRYCHDNNIIHRDVKPHCVLLASKENSAPVKLGGFGVA----IQLGESGLVAG 177
            M+Q++  L Y H N I+HRD+K   +L+  +     +KL  FG+A    + L +      
Sbjct: 1403 MKQLMNGLYYIHRNKILHRDMKAANILITKQ---GVLKLADFGLARAFSVNLRQPNRYT- 1236

Query: 178  GRVGTPHFMAPEVVKRE-PYGKPVDVWGCGVILFILLSGCLPFYGTKER-LFEGIIKGKY 235
             RV T  +  PE++  +  Y   +D WG G I+  + +      GT E+     I +   
Sbjct: 1235 NRVVTLWYRPPELLLGDRNYSTAIDQWGAGCIMAEMWTRNPIMQGTTEQNQLTLITQLCG 1056

Query: 236  KMNPRQWSHISESAKDLVRRMLMLDPAERITVYEALNHPW-----LKERDRYAYK 285
             + P  W  +                 ER+ +Y +L+ P      +KER RY  K
Sbjct: 1055 SITPEVWPGV-----------------ERLELYNSLDLPQGNKRKVKERLRYYIK 942
>11574
          Length = 1255

 Score = 72.8 bits (177), Expect = 6e-13,   Method: Compositional matrix adjust.
 Identities = 30/45 (66%), Positives = 38/45 (84%)
 Frame = +2

Query: 853 LQRTYAHYFDLTIINNEIDETIRHLEEAVELVCTAPQWVPVSWVY 897
           +++ Y H+FD  I+NN+IDETIR LE+A+E VCT PQWVPVSWVY
Sbjct: 14  VEKAYGHFFDRQIVNNDIDETIRTLEKAIEDVCTLPQWVPVSWVY 148
>01966
          Length = 1735

 Score = 72.8 bits (177), Expect = 7e-13,   Method: Compositional matrix adjust.
 Identities = 56/186 (30%), Positives = 92/186 (49%), Gaps = 3/186 (1%)
 Frame = -1

Query: 26   VRR---CINRETGQQFAVKIVDVAKFTSSPGLSTEDLKREASICHMLKHPHIVELLETYS 82
            VRR   C +R TG++ A+K + +    S  G+ +  + RE ++   L+H +IV L +   
Sbjct: 1672 VRRGL*CRHRATGRKLAMKKIRLRG--SEDGVPSSAI-REIAMLRELRHTNIVCLEDVIM 1502

Query: 83   SDGMLYMVFEFMDGADLCFEIVKRADAGFVYSEAVASHYMRQILEALRYCHDNNIIHRDV 142
             D  L++VFEF+   DL   I K  + G V    +   Y+ QI+  + +CH   I+HRD+
Sbjct: 1501 EDERLFLVFEFLS-MDLKMYIDKFPE-GVVLDRRLVKSYVFQIVTGINFCHQRRIVHRDL 1328

Query: 143  KPHCVLLASKENSAPVKLGGFGVAIQLGESGLVAGGRVGTPHFMAPEVVKREPYGKPVDV 202
            KP  +L+    ++  +K+  FG+A             V T  + APE++   P   P   
Sbjct: 1327 KPQNLLI---NHTGAIKIADFGMARTFALPVRAYTHEVVTLWYRAPEILM-GPQSTP-PX 1163

Query: 203  WGCGVI 208
            W CG +
Sbjct: 1162 WTCGAL 1145

 Score = 32.0 bits (71), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 31/120 (25%), Positives = 44/120 (36%), Gaps = 26/120 (21%)
 Frame = -3

Query: 196  YGKPVDVWGCGVILFILLSGCLPFYGTKE-----RLFEGIIKGKYKMNPR---------- 240
            Y  PVDVW  G I   +L     F G  E     ++F  I     +  P           
Sbjct: 1175 YSTPVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIFRIIGTPTEQTWPEFHKLPAFNGM 996

Query: 241  --QWSH--ISESAKDL-------VRRMLMLDPAERITVYEALNHPWLKERDRYAYKIHLP 289
               W    +SE+  DL       + R L  DPA+RI+  + L H +    D     + +P
Sbjct: 995  FPLWKEGKLSETLTDLDSLGLDLIERTLKCDPAQRISCKKMLQHAYFLNVDTSVKPVDVP 816
>01718
          Length = 959

 Score = 70.5 bits (171), Expect = 3e-12,   Method: Compositional matrix adjust.
 Identities = 50/201 (24%), Positives = 99/201 (49%), Gaps = 5/201 (2%)
 Frame = +3

Query: 14  LCEVIGKGPFSVVRRCINRETGQQFAVKIVDVAKFTSSPGLSTEDLKREASICHMLKHPH 73
           +CE IG G FS V +  +R TGQ  A+K+  +         +  ++ RE  + + L+H +
Sbjct: 159 ICEKIGAGFFSEVFKVTHRITGQVMALKMNTMTS-------NRHNMLREVQLLNRLQHAN 317

Query: 74  IVELLETYSSDGMLYMVFEFMDGADLCFEIVKRADAGFVYSEAVASHYMRQILEALRYCH 133
           I+  +     +G L+ + E++   +L  +++++ D    +++ +       +   L Y H
Sbjct: 318 ILRFMGVCVHEGQLHALTEYIPSGNL-EQLLEKKDEELPWTQRI--QLTLGLARGLDYLH 488

Query: 134 DNNIIHRDVKPHCVLLASKENSA-PVKLGGFGVAIQ----LGESGLVAGGRVGTPHFMAP 188
               IHRD+    +L+  ++N      +  FG+A +    L +  L     VG+P++MAP
Sbjct: 489 STRFIHRDLTSKNILIRREDNHGYHAVIADFGLATKIPDPLDKEKLPT---VGSPYWMAP 659

Query: 189 EVVKREPYGKPVDVWGCGVIL 209
           EV+    Y +  D++  G+I+
Sbjct: 660 EVLNGHFYNERADLFSVGIIM 722
>08480
          Length = 698

 Score = 67.0 bits (162), Expect = 3e-11,   Method: Compositional matrix adjust.
 Identities = 46/142 (32%), Positives = 70/142 (49%), Gaps = 18/142 (12%)
 Frame = -1

Query: 522 GTLHVGDEIREINGISVANQTVEQLQKMLREMRGSITFKIVPSYRTQS-----SSCEDLP 576
           G L  GD+I  +N + V   T EQ  + L+  R   T +I+  Y+ +      +  +DL 
Sbjct: 680 GDLRRGDKILSVNDVDVERATHEQAAQALK--RAGDTVEIIAQYKPEDYNRFEAKIQDLR 507

Query: 577 S-----------TTQPKGRQIYVRAQFEYDPAKDDLIPCKEAGIRFRVGDIIQIISKDDH 625
                       TTQ   R ++VRA F+Y+P+KD  +P +  G+ F  GDI+ + +  D 
Sbjct: 506 EQMMNNSAGSLRTTQK--RTMFVRALFDYEPSKDSGLPSR--GLWFHYGDILHVTNASDD 339

Query: 626 NWWQGK--LENSKNGTAGLIPS 645
            WWQ K  L + K    G+IPS
Sbjct: 338 EWWQAKRILPDGKEEGMGIIPS 273
>20152
          Length = 445

 Score = 66.2 bits (160), Expect = 6e-11,   Method: Compositional matrix adjust.
 Identities = 37/128 (28%), Positives = 66/128 (51%), Gaps = 7/128 (5%)
 Frame = +1

Query: 188 PEVVKREPYGKP-VDVWGCGVILFILLSGCLPFY-GTKERLFEGIIKGKYKMNPRQWSHI 245
           PE++  + Y  P VDVW  GVIL++L+ G  PF           I+  +Y++ P    HI
Sbjct: 1   PEILLGDSYDAPAVDVWSLGVILYMLVVGEAPFQEANDSETLTMIMDCRYQIPP----HI 168

Query: 246 SESAKDLVRRMLMLDPAERITVYEALNHPWLKERDRYAYKIHLPETVEQL-----RKFNA 300
           S   +DL+ +ML  +P +R ++   L HPWL + D      +LP   +++     + +  
Sbjct: 169 SHKCQDLIEKMLQREPVDRASLPHILAHPWLNDGDLTPTTAYLPLITKEMISEEDQTYVV 348

Query: 301 RRKLKGAV 308
           ++ ++G +
Sbjct: 349 QKMVEGKI 372
>26711
          Length = 405

 Score = 66.2 bits (160), Expect = 6e-11,   Method: Composition-based stats.
 Identities = 47/140 (33%), Positives = 77/140 (55%), Gaps = 8/140 (5%)
 Frame = -2

Query: 122 MRQILEALRYCHDNNIIHRDVKPHCVLLASKENSAPVKLGGFGVAIQL---GESGLVAGG 178
           ++Q+L+ L++ H   ++H D+KP  +LL S +    V+L  FG+A +L    E+ L    
Sbjct: 398 VKQVLDILQHVHAQGVVHMDLKPSNLLL-SGDKLDSVQLIDFGLARKLYPPQETFL---- 234

Query: 179 RVGTPHFMAPEVVKREPYGKPVDVWGCGVILFILLSGCLPFYGTKERLFEGIIKGK---- 234
             GTP F +PE +  +P     DVWG GV+ +ILLSG  PF    +   E + K +    
Sbjct: 233 NHGTPGFTSPEALDVKPISTASDVWGVGVLAYILLSGQSPFQA--DSATESLKKTQTCDW 60

Query: 235 -YKMNPRQWSHISESAKDLV 253
            + + P  +S++S+ AKD +
Sbjct: 59  SFDVCP-SFSNMSQDAKDFI 3
>06405
          Length = 1965

 Score = 65.1 bits (157), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 59/225 (26%), Positives = 98/225 (43%), Gaps = 5/225 (2%)
 Frame = +1

Query: 18  IGKGPFSVVRRCINRETGQQFAVKIVDVAKFTSSPGLSTEDLKREASICHMLKHPHIVEL 77
           +G G +  V   + +   +  AVK +          ++  D   EA+I   +KHP++V+L
Sbjct: 283 LGGGQYGDVYEAMWKRYNKIVAVKTL------KEDTMALNDFLEEAAIMKEMKHPNLVQL 444

Query: 78  LETYSSDGMLYMVFEFMDGADLC--FEIVKRADAGFVYSEAVASHYM-RQILEALRYCHD 134
           L   + +   Y+V EFM   +L        R + G       A  YM  QI   + Y   
Sbjct: 445 LGVCTREPPFYIVTEFMPHGNLLDYLRSSTREENG-----PTALMYMATQIASGMAYLET 609

Query: 135 NNIIHRDVKPHCVLLASKENSAPVKLGGFGVAIQLGESGLVAGGRVGTP-HFMAPEVVKR 193
            N IHRD+     L+A   +S  VK+  FG+A  + +    A      P  + APE +  
Sbjct: 610 KNFIHRDLAARNCLVA---DSNMVKVADFGLARLMKDDTYTAHIGAKFPIKWTAPEGLAF 780

Query: 194 EPYGKPVDVWGCGVILFILLS-GCLPFYGTKERLFEGIIKGKYKM 237
             +    D+W  GV+L+ L + G  P+ G +      +++  Y+M
Sbjct: 781 NRFSTRSDIWAFGVLLWELATYGMSPYPGVELTEVYHLLERGYRM 915
>00486
          Length = 797

 Score = 64.3 bits (155), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 29/86 (33%), Positives = 54/86 (62%), Gaps = 1/86 (1%)
 Frame = -2

Query: 181 GTPHFMAPEVVKREPYGKPVDVWGCGVILFILLSGCLPFYG-TKERLFEGIIKGKYKMNP 239
           GT  +MAPE++ R  +GK VD W  G +++ +L+G  PF    +++  + I+KGK  + P
Sbjct: 772 GTIEYMAPEILTRTGHGKAVDWWSLGALMYDMLTGSPPFTAENRKKTIDKILKGKLNLPP 593

Query: 240 RQWSHISESAKDLVRRMLMLDPAERI 265
               +++  A+ L++++L  +PAER+
Sbjct: 592 ----YLTNEARGLIKKLLRKNPAERL 527
>09007
          Length = 1440

 Score = 64.3 bits (155), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 59/226 (26%), Positives = 98/226 (43%), Gaps = 10/226 (4%)
 Frame = -1

Query: 6   VLFEDVYELCEVIGKGPFSVVRRCI-NRETGQ--QFAVKIVDVAKFTSSPGLSTEDLKRE 62
           ++ +D   L + +G+G F  VR+ I   E+G+  Q AVK +   K         ++  +E
Sbjct: 891 LISKDCVALSKSLGQGHFGTVRQAIWTAESGEKVQVAVKCLSKDKIHKD----GQEFLKE 724

Query: 63  ASICHMLKHPHIVELLETYSSDGMLYMVFEFMDGADLCFEIVKRADAGFVYSEAVASHYM 122
            +I  ML H +IV +      +G   M+   +       E VK   A   +S      + 
Sbjct: 723 TAIMQMLDHENIVRVYGVVMDNGADIMLVTELAPMRSLLECVKEVSARVDFSVPRLCDFS 544

Query: 123 RQILEALRYCHDNNIIHRDVKPHCVLLASKENSAPVKLGGFGVAIQLGESGLVAGGRVGT 182
           +Q+ + + Y     ++HRD+    +LL SK     VK+   GV+  LG +G        T
Sbjct: 543 QQVCDGMSYLESKRLVHRDLAARNILLFSKSK---VKISDVGVSGALG-AGKEYYQSQQT 376

Query: 183 PH------FMAPEVVKREPYGKPVDVWGCGVILFILLS-GCLPFYG 221
            H      + APE  +   +    DVW  GV+L+   + G  P+ G
Sbjct: 375 IHLQNAVAWCAPESFRNLCFSSASDVWAFGVLLWEFFTHGFQPWAG 238
>13066
          Length = 551

 Score = 63.5 bits (153), Expect = 4e-10,   Method: Compositional matrix adjust.
 Identities = 57/188 (30%), Positives = 84/188 (44%), Gaps = 6/188 (3%)
 Frame = +3

Query: 25  VVRRCINRETGQ--QFAVKIVDVAKFTSSPGLSTEDLKREASICHMLKHPHIVELLETYS 82
           VV    N   G+  + A KI+D  K  +      +   RE  +   L HP+I+++     
Sbjct: 15  VVHGTFNDGYGRNIKLACKIIDKEK--APVDFVEKFFPRELDLLTKLDHPYIIQIHSILQ 188

Query: 83  SDGMLYMVFEFMDGADLCFEIVKRADAGFVYSEAVASHYMRQILEALRYCHDNNIIHRDV 142
                ++   F +  DL   I    + GFV  E  A  +  Q+  AL Y H  ++ HRD+
Sbjct: 189 RXPKNFIFMRFAERGDLLTYI---QEVGFV-KEKQAKIWFYQMTTALNYLHSYDVAHRDL 356

Query: 143 KPHCVLLASKENSAPVKLGGFGVAIQ-LGESG--LVAGGRVGTPHFMAPEVVKREPYG-K 198
           K   +LL+S  N   VKL  FG A   + ESG   ++    G+  + APE+V   PY  K
Sbjct: 357 KCENILLSSHFN---VKLADFGFACACITESGEKYMSRTYCGSAAYAAPEIVYGAPYAPK 527

Query: 199 PVDVWGCG 206
             D W  G
Sbjct: 528 VADAWSLG 551
>04591
          Length = 1117

 Score = 62.8 bits (151), Expect = 6e-10,   Method: Compositional matrix adjust.
 Identities = 66/252 (26%), Positives = 107/252 (42%), Gaps = 39/252 (15%)
 Frame = -2

Query: 61   REASICHMLKHPHIVELLETYSSDG--------MLYMVFEFMDGADLCFEIVKRADAGFV 112
            RE  I   L+H ++V+L E   +            Y++FE+ D  DL   +    +    
Sbjct: 1074 REIKILQQLEHENVVQLQEICHTQAGPYNRYKSTFYLIFEYCD-YDLAGLL---NNLRVK 907

Query: 113  YSEAVASHYMRQILEALRYCHDNNIIHRDVKPHCVLLASKENSAPVKLGGFGVAIQLGES 172
            +S A   + M Q+L  L Y H   I+HRD+K   +LL        +KL  FG++    +S
Sbjct: 906  FSLADKKNLMSQLLNGLFYIHTKQILHRDIKAANILLT---RDGVLKLADFGLSRPWVKS 736

Query: 173  GLVAGGRVGTPHFMAPEVV--KREPYGKPVDVWGCGVILFILLSGCLPFYGTKER----- 225
              +   RV T  +  PE++  +RE YG  +D+WG G I+  + S      G  E+     
Sbjct: 735  KRLT-NRVVTLWYRPPELLLGERE-YGPEIDMWGVGCIMAEMWSRKPLMQGRSEQHQLSL 562

Query: 226  -----------LFEGIIK----GKYKMNPRQWSHISESAKDLVRR---------MLMLDP 261
                       ++ G+ K    GK  +   +   + E   DL++           L LDP
Sbjct: 561  ITDLCGSLNAEVWPGVTKLELYGKLDLPQGKPRKVKERMLDLLKNKEGAELIDIFLRLDP 382

Query: 262  AERITVYEALNH 273
             +R+    AL+H
Sbjct: 381  GQRMNCDNALSH 346
>28638
          Length = 1458

 Score = 48.5 bits (114), Expect(2) = 6e-10,   Method: Compositional matrix adjust.
 Identities = 30/91 (32%), Positives = 50/91 (54%), Gaps = 2/91 (2%)
 Frame = -1

Query: 121 YMRQILEALRYCH--DNNIIHRDVKPHCVLLASKENSAPVKLGGFGVAIQLGESGLVAGG 178
           + +Q+  AL +    + NIIH D+KP  +LL + + SA +K+  FG + QLG+       
Sbjct: 822 FAQQLCTALLFLATPEMNIIHCDLKPENILLCNPKRSA-IKIVDFGSSCQLGQR---IYQ 655

Query: 179 RVGTPHFMAPEVVKREPYGKPVDVWGCGVIL 209
            + +  + +PEV+   PY   +D+W  G IL
Sbjct: 654 YIQSRFYRSPEVLLGVPYDLAIDMWSLGCIL 562

 Score = 34.3 bits (77), Expect(2) = 6e-10,   Method: Compositional matrix adjust.
 Identities = 26/100 (26%), Positives = 46/100 (46%), Gaps = 5/100 (5%)
 Frame = -3

Query: 10   DVYELCEVIGKGPFSVVRRCINRETGQQFAVKIVDVAKFTSSPGLSTEDLKREASICHML 69
            D YE+  +IGKG F  V +  +    +Q A+KI+   K    P L+   ++ +       
Sbjct: 1147 DRYEIDSLIGKGSFGQVVKAYDHGDQEQVAIKIIKNKK----PFLNQAQIEVK------- 1001

Query: 70   KHPHIVELLETYSSDGMLYMV-----FEFMDGADLCFEIV 104
                ++EL+  + +D   Y+V     F F +   L FE++
Sbjct: 1000 ----LLELMNRHDADNXYYIVRLKRHFMFRNHLCLVFELL 893

 Score = 32.7 bits (73), Expect = 0.62,   Method: Composition-based stats.
 Identities = 14/29 (48%), Positives = 19/29 (65%)
 Frame = -2

Query: 250 KDLVRRMLMLDPAERITVYEALNHPWLKE 278
           KDL+ RML  DP  RI+ Y AL H + ++
Sbjct: 260 KDLILRMLDFDPKTRISPYYALQHNFFRK 174
>29590
          Length = 320

 Score = 50.4 bits (119), Expect(2) = 7e-10,   Method: Composition-based stats.
 Identities = 18/46 (39%), Positives = 29/46 (63%)
 Frame = +3

Query: 180 VGTPHFMAPEVVKREPYGKPVDVWGCGVILFILLSGCLPFYGTKER 225
           +GTP ++APEV+  EP     D+W  GV+ +++L+ C PF G   +
Sbjct: 57  IGTPDYVAPEVLDYEPLSIQTDMWSLGVLSYVMLTACSPFVGITSK 194

 Score = 32.0 bits (71), Expect(2) = 7e-10,   Method: Compositional matrix adjust.
 Identities = 15/45 (33%), Positives = 25/45 (55%)
 Frame = +2

Query: 222 TKERLFEGIIKGKYKMNPRQWSHISESAKDLVRRMLMLDPAERIT 266
            ++  F  I + K       +SHIS  AKD ++++L+ DP  R+T
Sbjct: 185 NQQETFCNISQVKLDFPDDLFSHISPHAKDFIKKLLVKDPRHRMT 319
>09606
          Length = 1300

 Score = 62.4 bits (150), Expect = 7e-10,   Method: Compositional matrix adjust.
 Identities = 61/289 (21%), Positives = 116/289 (40%), Gaps = 27/289 (9%)
 Frame = -3

Query: 12   YELCEVIGKGPFSVVRRCINRETGQQFAVKIVDVAKFTSSPGLSTEDLKREASICHMLKH 71
            + L E +GKG  S++ +   + T    A+  ++  K          ++     + H + H
Sbjct: 1109 FVLYEELGKGEHSIIYKGRRKGTINFVAIHCIEKCK--------RPEVTNTVRMTHDISH 954

Query: 72   PHIVELLETYSSDGMLYMVFEFMDGADLCFEIVKRADAGFVYSEAVASHYMRQILEALRY 131
            P++V+  E Y +   L++V E   G  L  +I+ +        E     +   ++  L Y
Sbjct: 953  PNVVQFHEWYETSNHLWLVVELCTGGSLA-DILAQDHH---LPETSIRDFGIHLVTGLHY 786

Query: 132  CHDNNIIHRDVKPHCVLLASKENSAPVKLGGFGVA----------------------IQL 169
             H   I+  D++P  VLL   + S  +K   FG++                      IQ 
Sbjct: 785  IHSLGILFHDLRPSKVLL---DTSGVLKFADFGLSKVEGENLEELFFKFAEAGDQWNIQS 615

Query: 170  GESGLVAGGRVGTPHFMAPEVVKREPYGKPVDVWGCGVILFILLSGCLPFYG-TKERLFE 228
             E  +      G+P +MAPEV +        D+W  G + + + SG  PF G T +   +
Sbjct: 614  AEEMMKQVPTSGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFSGHPPFLGETYDITKD 435

Query: 229  GIIKGKYKMNPRQWSHISESAK----DLVRRMLMLDPAERITVYEALNH 273
             ++  ++ +   + S +S        +L+  +L  D   R++    + H
Sbjct: 434  KVLNKEFPLPKVKGSRLSAKPSPEFLNLLESLLQKDSTRRLSWASLVKH 288
>00392
          Length = 668

 Score = 62.4 bits (150), Expect = 9e-10,   Method: Compositional matrix adjust.
 Identities = 49/170 (28%), Positives = 81/170 (47%), Gaps = 7/170 (4%)
 Frame = +3

Query: 57  EDLKREASICHMLKHPHIVELLETYSSDG-----MLYMVFEFMDGADLCFEIVKRADAGF 111
           +  K EA +   L+HP+IV   + +         ++ +V E M    L    +KR     
Sbjct: 66  QRFKEEAEMLKELQHPNIVRFFDYWEEHNHRNRKVIILVTELMTSGTL-KTYLKRFKKPN 242

Query: 112 VYSEAVASHYMRQILEALRYCHDNN--IIHRDVKPHCVLLASKENSAPVKLGGFGVAIQL 169
           V    +  ++ RQ+L+ L + H     +IHRD+K   + +     S  VK+G  G+A   
Sbjct: 243 V---KILKNWCRQVLKGLYFLHTRTPPVIHRDLKCDNIFITGPTGS--VKIGDLGLATLK 407

Query: 170 GESGLVAGGRVGTPHFMAPEVVKREPYGKPVDVWGCGVILFILLSGCLPF 219
            +S   A   +GTP FMAPE+ + E Y + VDV+  G+ +  + S   P+
Sbjct: 408 NQS--FAKSVIGTPEFMAPEMYE-EHYDEAVDVYAFGMCMLEMASSEYPY 548
>29581
          Length = 1278

 Score = 62.0 bits (149), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 66/242 (27%), Positives = 105/242 (43%), Gaps = 31/242 (12%)
 Frame = -2

Query: 69   LKHPHIVELLETYSSDGM--LYMVFEFMDGADLCFEIVKRADAGFVYSEAVASHYMRQIL 126
            L+H +IV+L E      +  L++V E+ +  DL   ++    A F  SE+     + Q+L
Sbjct: 1184 LRHQNIVQLQEVVVGKSLDSLFLVMEYCE-QDLA-SLLDNMPAPF--SESQVKCIVLQLL 1017

Query: 127  EALRYCHDNNIIHRDVKPHCVLLASKENSAPVKLGGFGVAIQLGESGLVAGGRVGTPHFM 186
            + LRY H+  IIHRD+K   +L+  K     VK+  FG+A   G+       +V T  + 
Sbjct: 1016 KGLRYLHEAFIIHRDLKVSNLLMTDK---GCVKIADFGLARNYGKPQKPMTPKVVTLWYR 846

Query: 187  APEVV-KREPYGKPVDVWGCGVILFILLSGCLPFYGTKERL------------------- 226
            APE++   + +   +D+W  G IL  LL G  P    +  L                   
Sbjct: 845  APELLFGSKTHSTAIDMWSAGCILGELL-GHKPLMPGRSDLQQIELIMELLGTPNDTIWP 669

Query: 227  -------FEGIIKGKYKMNPRQ--WSHISESAKDLVRRMLMLDPAERITVYEALNHPWLK 277
                   FE     K   N  +  +  +SES   L+  + M  P +R T  + L H + K
Sbjct: 668  GFSQLPAFEQFTLKKQPYNNLRHTFPWLSESGIRLLNGLFMYHPQKRATAEDCLEHSYFK 489

Query: 278  ER 279
            E+
Sbjct: 488  EQ 483
>19761
          Length = 473

 Score = 60.5 bits (145), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 41/146 (28%), Positives = 71/146 (48%), Gaps = 6/146 (4%)
 Frame = -3

Query: 121 YMRQILEALRYCHDNN--IIHRDVKPHCVLLASKENSAPVKLGGFGVAIQLGESGLVAGG 178
           ++ Q   AL Y H +   I+HRD+KP  + +  K +   V+LG  G+A +L      A  
Sbjct: 408 WLMQTASALNYMHTHTPVILHRDLKPQNIYVTEKGD---VRLGDLGLARKLTGPADFATS 238

Query: 179 RVGTPHFMAPEVVKREPYGKPVDVWGCGVILFILLSGCLPFYGTKER----LFEGIIKGK 234
           +VGT  +++PE++ ++PY    D+W  G + + +        G+ E     L   ++ G+
Sbjct: 237 QVGTIMYLSPEILSQQPYNSKSDIWSLGCVFYDITGK----KGSDEMGVMFLLVQVMGGR 70

Query: 235 YKMNPRQWSHISESAKDLVRRMLMLD 260
               P    H S+  +D + RML  D
Sbjct: 69  KLPLP---DHYSQEFRDTISRMLTKD 1
>19094
          Length = 898

 Score = 60.1 bits (144), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 34/92 (36%), Positives = 47/92 (51%)
 Frame = +1

Query: 126 LEALRYCHDNNIIHRDVKPHCVLLASKENSAPVKLGGFGVAIQLGESGLVAGGRVGTPHF 185
           L+ L Y H    IHRD+K   +LL    N    KL  FGVA QL ++       +GTP++
Sbjct: 88  LKGL*YLHSRRKIHRDIKAGNILL---NNEGHAKLADFGVAGQLTDTMAKRNTVIGTPYW 258

Query: 186 MAPEVVKREPYGKPVDVWGCGVILFILLSGCL 217
           MAPEV++   Y    D+W  G+    +  G L
Sbjct: 259 MAPEVIQEIGYDCVADIWSLGITALEMAEGNL 354
>12786
          Length = 460

 Score = 59.3 bits (142), Expect = 6e-09,   Method: Compositional matrix adjust.
 Identities = 37/128 (28%), Positives = 62/128 (48%), Gaps = 22/128 (17%)
 Frame = -3

Query: 121 YMRQILEALRYCHDNNIIHRDVKPHCVLLASKENSAPVKLGGFGVA--IQLGESGLVAGG 178
           Y R++L A++  H+  +IH D+KP   +L     +  +KL  FG+A  +Q  ++ ++   
Sbjct: 395 YWREMLRAVKALHNEGVIHSDLKPANFMLV----AGNLKLIDFGIANTLQQDKTSVLKDS 228

Query: 179 RVGTPHFMAPEVV-----------------KREP---YGKPVDVWGCGVILFILLSGCLP 218
           RVGTP +M+PE +                 + +P    G   DVW  G IL+ ++ G  P
Sbjct: 227 RVGTPSYMSPEAIMAACDDSADDSMEEDGHRTKPKYKVGVRSDVWSLGCILYNMVYGRTP 48

Query: 219 FYGTKERL 226
           F   K  +
Sbjct: 47  FQHIKNNM 24
>38560
          Length = 479

 Score = 57.8 bits (138), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 35/99 (35%), Positives = 51/99 (51%), Gaps = 1/99 (1%)
 Frame = -3

Query: 181 GTPHFMAPEVVKREPY-GKPVDVWGCGVILFILLSGCLPFYGTKERLFEGIIKGKYKMNP 239
           G+P + APE++    Y G   D+W  GV+L+ LL G LPF   K        + +    P
Sbjct: 399 GSPAYAAPELISGLEYLGSEADIWSMGVLLYALLCGYLPFDDEKXSHL*QKNQKRKDEVP 220

Query: 240 RQWSHISESAKDLVRRMLMLDPAERITVYEALNHPWLKE 278
            +W  +SE    L+  ML  DP+ RIT+   L+H WL +
Sbjct: 219 -EW--LSEDTTKLLEGMLQTDPSHRITIRRLLDHHWLNQ 112
>18663
          Length = 600

 Score = 57.8 bits (138), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 35/113 (30%), Positives = 63/113 (55%), Gaps = 16/113 (14%)
 Frame = +2

Query: 181 GTPHFMAPEVVKREPYGKPVDVWGCGVILFILLSGCLPF----------YGTKERLFEGI 230
           GTP+++APE+++ E YG  VD W  GV+L+ +L+G  PF            T++ LF+ I
Sbjct: 14  GTPNYIAPEILRGEDYGFSVDWWALGVLLYEMLAGRSPFDIAGASENPDQNTEDYLFQVI 193

Query: 231 IKGKYKMNPRQWSHISESAKDLVRRMLMLDPAERITVY------EALNHPWLK 277
           ++   ++ PR    +S  A  +++  L  +PA+R+  +      + +NHP+ K
Sbjct: 194 LEKTIRI-PRS---LSVKAASVLKGFLNKNPADRLGCHRESAFMDIVNHPFFK 340
>03508
          Length = 1463

 Score = 55.8 bits (133), Expect = 8e-08,   Method: Compositional matrix adjust.
 Identities = 33/115 (28%), Positives = 61/115 (53%), Gaps = 4/115 (3%)
 Frame = +1

Query: 99  LCFEIVKRADAGFVY---SEAVASHYMRQILEALRYCHDNNIIHRDVKPHCVLLASKENS 155
           L FE V   D   +Y   ++     Y+ ++++AL +CH   I+HRDVKPH V++  +  +
Sbjct: 811 LIFEHVNNTDFKQLYQTFTDYDIRFYLYELMKALDFCHSMGIMHRDVKPHNVMIDHE--N 984

Query: 156 APVKLGGFGVAIQLGESGLVAGGRVGTPHFMAPE-VVKREPYGKPVDVWGCGVIL 209
             ++L  +G+A +    G+    RV + +F  PE ++  + Y   +D+W  G + 
Sbjct: 985 KKLRLIDWGLA-EFYHPGMEYNVRVASRYFKGPELLLDYQMYDYSLDMWSLGCMF 1146
>27405
          Length = 532

 Score = 55.1 bits (131), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 45/184 (24%), Positives = 84/184 (45%), Gaps = 3/184 (1%)
 Frame = -3

Query: 23  FSVVRRCINRETGQQFAVKIVDVAKFTSSPG--LSTEDLKREASICHMLKHPHIVELLET 80
           F  V  C   +TG+ +A+K +D  +     G  L+  +    + +      P IV +   
Sbjct: 527 FGEVYGCRKADTGKMYAMKCLDKKRIKMKGGETLALNERIMLSLVSTGEGSPFIVCMTYA 348

Query: 81  YSSDGMLYMVFEFMDGADLCFEIVKRADAGFVYSEAVASHYMRQILEALRYCHDNNIIHR 140
           + +   L  + + M+G DL + + +      V++E     Y  +++  L + H   +++R
Sbjct: 347 FQTPEKLCFILDLMNGGDLHYHLSQHG----VFTEKEVRFYAAEVMLGLEHMHSRFVVYR 180

Query: 141 DVKPHCVLLASKENSAPVKLGGFGVAIQLGESGLVAGGRVGTPHFMAPEVV-KREPYGKP 199
           D+KP  +LL   + +  V++   G+A    +    A   VGT  +MAPEV+ K + Y   
Sbjct: 179 DLKPANILL---DENGHVRISDLGLACDFSKKKPHA--SVGTHGYMAPEVLMKGQAYDSS 15

Query: 200 VDVW 203
            D W
Sbjct: 14  AD-W 6
>04852
          Length = 1462

 Score = 53.9 bits (128), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 57/242 (23%), Positives = 103/242 (42%), Gaps = 24/242 (9%)
 Frame = +1

Query: 56  TEDLKREASICHMLKHPHIVELLETYSSDGMLYMVFEFM-------------DGADLCFE 102
            ++L+   ++  M  H +IV  L   +  G L+++ EF              DG +   +
Sbjct: 82  VQELQVMKAVKKMGSHINIVNFLGCCTQGGPLWVIVEFAKNGNLRDFLESCRDGINGYGK 261

Query: 103 IVKRADAGFVYSEAVASHYMR---------QILEALRYCHDNNIIHRDVKPHCVLLASKE 153
            V   D G+ Y++    H +R         QI   + +      IHRD+    VL+  + 
Sbjct: 262 FVSPQDPGW-YTKTPGGHVIRRKNLLSYAFQIARGMEFLASRKCIHRDLAARNVLVTEEH 438

Query: 154 NSAPVKLGGFGVAIQLGESGLVAGGRVGTPHFMAPEVVKREPYGKPVDVWGCGVILFILL 213
               +K+  FG++         +GGR+    +MAPE +    Y    DVW  GV+L+ + 
Sbjct: 439 ---VLKIADFGLSRTGDYYKKRSGGRLPV-KWMAPEALFDMRYTTKSDVWSFGVVLWEIF 606

Query: 214 S-GCLPFYGT-KERLFEGIIKGKYKMNPRQWSHISESAKDLVRRMLMLDPAERITVYEAL 271
           S G +P+     E L+  ++   Y+M PR     S +   ++ R  +  P++R    + +
Sbjct: 607 SLGGMPYASIPNEELYSKLLDDAYRM-PRP-ELASGNLYAIMERCWLNRPSDRPEFSQLV 780

Query: 272 NH 273
            H
Sbjct: 781 GH 786
>21808
          Length = 1011

 Score = 52.8 bits (125), Expect = 6e-07,   Method: Compositional matrix adjust.
 Identities = 47/179 (26%), Positives = 76/179 (42%), Gaps = 4/179 (2%)
 Frame = +1

Query: 47  KFTSSPGLSTEDLKREASICHMLKHPHIVELLETYSSDGMLYMVFEFMDGADLCFEIVKR 106
           K   S  +  +D   EA I   L+HP +++L    + D  ++++ E M    L  E ++ 
Sbjct: 37  KTLKSGTMDPKDFLAEAQIMKKLRHPKLIQLYAVCTQDDPIFIITELMKNGSL-LEFLQ- 210

Query: 107 ADAGFVYSEAVASHYMRQILEALRYCHDNNIIHRDVKPHCVLLASKENSAPVKLGGFGVA 166
              G V           QI   + Y    N IHRD+    +L++       VK+  FG+A
Sbjct: 211 -GKGRVLKLPALIDIGAQIACGMAYLESQNYIHRDLAARNILVSDNNT---VKIADFGLA 378

Query: 167 IQLGESGLVAGGRVGTP---HFMAPEVVKREPYGKPVDVWGCGVILFILLS-GCLPFYG 221
             + E    A  RVG      + APE      +    DVW  G++L   ++ G +P+ G
Sbjct: 379 RVIKEDEYEA--RVGARFPIKWTAPEAANYNRFTIKSDVWSFGILLTETVTYGRVPYPG 549
>26560
          Length = 398

 Score = 52.4 bits (124), Expect = 9e-07,   Method: Compositional matrix adjust.
 Identities = 33/109 (30%), Positives = 56/109 (51%), Gaps = 1/109 (0%)
 Frame = -1

Query: 112 VYSEAVASHYMRQILEALRYCHDNNIIHRDVKPHCVLLASKENSAPVKLGGFGVAIQLGE 171
           V++E     Y  +++  L + H   +++RD+KP  +LL   + +  V++   G+A    +
Sbjct: 368 VFTEKEVRFYAAEVMLGLEHMHSRFVVYRDLKPANILL---DENGHVRISDLGLACDFSK 198

Query: 172 SGLVAGGRVGTPHFMAPEVV-KREPYGKPVDVWGCGVILFILLSGCLPF 219
               A   VGT  +MAPEV+ K + Y    D +  G +L+ LL G  PF
Sbjct: 197 KRPHAS--VGTHGYMAPEVLMKGQSYDSSADWFSFGCMLYKLLKGHSPF 57
>33158
          Length = 1075

 Score = 51.6 bits (122), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 48/181 (26%), Positives = 84/181 (46%), Gaps = 5/181 (2%)
 Frame = +2

Query: 355 TDCSEKDLDFLHSVFQDQHLHTLLDLYDKIN--TKSSPQIRNPPSDAVQRAKEVLE---E 409
           +   ++++ FL  +F +      +D++ K+   T  SP  R   SD+ + A +V     E
Sbjct: 575 SSTGQQEVHFLKQLFHNPLFQQTVDMHQKMVDVTSRSPLPRPLGSDSQELACDVKSYGSE 754

Query: 410 ISCYPENNDAKELKRILTQPHFMALLQTHDVVAHEVYSDEALRVTPPPTSPYLNGDSPES 469
           +         +EL  +L +P    LL+ HD VA +             T P L+    + 
Sbjct: 755 MGGSXSEAVVEELSMLLDKPALKNLLKAHDEVADQ------------QTHPILHVSESDL 898

Query: 470 ANGDMDMENVTRVRLVQFQKNTDEPMGITLKMNELNHCIVARIMHGGMIHRQGTLHVGDE 529
            +  +       V+++  +K T+E +G T+K NE +  ++ARI+ GG   + G LH GDE
Sbjct: 899 IDYPLTEYGEESVKIIHLEK-TNEHLGATVK-NEGDSVLIARIVKGGAAEKSGLLHEGDE 1072

Query: 530 I 530
           I
Sbjct: 1073I 1075
>37412
          Length = 757

 Score = 51.6 bits (122), Expect = 1e-06,   Method: Composition-based stats.
 Identities = 37/137 (27%), Positives = 58/137 (42%), Gaps = 22/137 (16%)
 Frame = -1

Query: 767 MMQDISNNEYLEYGSHEDAMYGTKLETIRKIHEQGLIAILDVEPQALKVLRTAEFAPFVV 826
           M  DI +  YLEYG     +YGT+L+T+R+I + G            K  R     P   
Sbjct: 730 MESDIMSGRYLEYGDFNGNLYGTRLDTVRQIVDSGRCVCWTSTLPH*KSSRRPSSCP--T 557

Query: 827 FIAAPTITPGLNE-----DESLQ-----------------RLQKESDVLQRTYAHYFDLT 864
             ++P +   L++     D+ L                     KES  ++R YA YFD  
Sbjct: 556 LCSSPRLAWKLSKSCTKMDDGLHAAAGSVVELK*NGGNFIETMKESQQIERVYASYFDDI 377

Query: 865 IINNEIDETIRHLEEAV 881
           I+N+  ++T R L  ++
Sbjct: 376 IVNDSFEDTYRQLRRSL 326
>36002
          Length = 253

 Score = 51.6 bits (122), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 23/55 (41%), Positives = 33/55 (60%)
 Frame = +1

Query: 222 TKERLFEGIIKGKYKMNPRQWSHISESAKDLVRRMLMLDPAERITVYEALNHPWL 276
            +E LF  I  G Y     +WS IS SAKDL+R +L+ +P +R +  + L HPW+
Sbjct: 46  CQELLFNRIQDGNYFFPSMEWSAISSSAKDLIRHLLVREPRKRYSAADVLKHPWV 210
>21433
          Length = 590

 Score = 51.6 bits (122), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 39/137 (28%), Positives = 66/137 (48%)
 Frame = +2

Query: 121 YMRQILEALRYCHDNNIIHRDVKPHCVLLASKENSAPVKLGGFGVAIQLGESGLVAGGRV 180
           Y+ Q+  AL YCH   +IHRD+KP  +LL  K +     +  FG ++    S        
Sbjct: 182 YIYQLSSALEYCHYRKVIHRDIKPENLLLGLKGDLK---IADFGWSVHAPSSRRTT--MC 346

Query: 181 GTPHFMAPEVVKREPYGKPVDVWGCGVILFILLSGCLPFYGTKERLFEGIIKGKYKMNPR 240
           GT  ++ PE+V+ + + + VD+W  GV+ +  L G  P   +  R            +P 
Sbjct: 347 GTLDYLPPEMVEGKTHDENVDLWSLGVLCYEFLVGTPPLRPSPTRPPTPASPRWTSGSP- 523

Query: 241 QWSHISESAKDLVRRML 257
             S ++  A+DL+ ++L
Sbjct: 524 --SIVTPGARDLISKLL 568
>27274
          Length = 396

 Score = 50.8 bits (120), Expect = 3e-06,   Method: Composition-based stats.
 Identities = 28/97 (28%), Positives = 55/97 (56%), Gaps = 9/97 (9%)
 Frame = -1

Query: 189 EVVKREPYGKPVDVWGCGVILFILLSGCLPF---YGTKER------LFEGIIKGKYKMNP 239
           E+++ + +G  VD+W  G++L  LLSG +PF    G+++       ++  II+G  + + 
Sbjct: 375 ELLRGQQHGPTVDMWSLGILLHELLSGHVPFEPERGSRQMARNMMAVYAQIIRGSSR-DV 199

Query: 240 RQWSHISESAKDLVRRMLMLDPAERITVYEALNHPWL 276
                +S    D +RR++ L+  +R+T  +A +HPW+
Sbjct: 198 CDGLALSTHGADFLRRLVQLEDTKRLTSQQAFSHPWI 88
>04138
          Length = 800

 Score = 49.7 bits (117), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 47/183 (25%), Positives = 76/183 (41%), Gaps = 36/183 (19%)
 Frame = +1

Query: 127 EALRYCHDNNIIHRDVKPHCVLLASKENSAPVKLGGFGVA----IQLGESGLVAGGRVGT 182
           E L Y H N I+HRD+K   +L+  +     +KL  FG+A    + L +       RV T
Sbjct: 46  ERLYYIHRNKILHRDMKAANILITKQ---GVLKLADFGLARAFSVNLRQPNRYT-NRVVT 213

Query: 183 PHFMAPEVVKRE-PYGKPVDVWGCGVILFILLSGCLPFYGTKER-LFEGIIKGKYKMNPR 240
             +  PE++  +  Y   +D WG G I+  + +      GT E+     I +    + P 
Sbjct: 214 LWYRPPELLLGDRNYSTAIDQWGAGCIMAEMWTRNPIMQGTTEQNQLTLITQLCGSITPE 393

Query: 241 QWSHISESAK------------------------------DLVRRMLMLDPAERITVYEA 270
            W  +++ +                               DL  R+L +DP++RI+  EA
Sbjct: 394 VWPGVTQLSMYHQIKGALAAGRKNIIRDRFARILKDPYGLDLFERLLKMDPSQRISADEA 573

Query: 271 LNH 273
           LNH
Sbjct: 574 LNH 582
>31120
          Length = 439

 Score = 49.7 bits (117), Expect = 6e-06,   Method: Composition-based stats.
 Identities = 34/94 (36%), Positives = 47/94 (50%), Gaps = 2/94 (2%)
 Frame = +1

Query: 189 EVVKREPYG-KPVDVWGCGVILFILLSGCLPFYGTK-ERLFEGIIKGKYKMNPRQWSHIS 246
           EVV   PY  K  D W  GVILFI+L+G +PF  +   +L E     KY    +    +S
Sbjct: 1   EVVCGVPYDPKMADAWSLGVILFIMLNGKMPFDDSNLNKLLEDQRSKKYSFRRKLQDLVS 180

Query: 247 ESAKDLVRRMLMLDPAERITVYEALNHPWLKERD 280
            +A+  V  +L  + A R  + E LN  WL+  D
Sbjct: 181 PNARSTVSVLLEPNSAMRWDLNEVLNCQWLQTID 282
>27546
          Length = 426

 Score = 48.5 bits (114), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 37/132 (28%), Positives = 61/132 (46%)
 Frame = -1

Query: 35  GQQFAVKIVDVAKFTSSPGLSTEDLKREASICHMLKHPHIVELLETYSSDGMLYMVFEFM 94
           G   A KI+D AK  +      +   RE  I   L HP+I+++         +++   + 
Sbjct: 405 GVNLACKIIDKAK--APIDFVKKFFPRELEILTRLDHPNIIQIHSILQRGPKIFIFMRYA 232

Query: 95  DGADLCFEIVKRADAGFVYSEAVASHYMRQILEALRYCHDNNIIHRDVKPHCVLLASKEN 154
           +  D+   I K         EA    +  Q+ +AL+Y H ++I HRD+K   +LL+ + N
Sbjct: 231 EKGDMLSHIKKTGPI----DEAQTKVWFFQMAKALQYLHSHDIAHRDLKCENILLSKRLN 64

Query: 155 SAPVKLGGFGVA 166
              VK+  FG A
Sbjct: 63  ---VKIADFGFA 37
>20559
          Length = 430

 Score = 36.2 bits (82), Expect(2) = 4e-05,   Method: Composition-based stats.
 Identities = 28/80 (35%), Positives = 41/80 (51%)
 Frame = -2

Query: 12  YELCEVIGKGPFSVVRRCINRETGQQFAVKIVDVAKFTSSPGLSTEDLKREASICHMLKH 71
           YE  E IG+G +  V +  NRET +  A+K V +       G+ +  L RE  +   LKH
Sbjct: 369 YEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDD--DDEGVPSSAL-REICLLKELKH 199

Query: 72  PHIVELLETYSSDGMLYMVF 91
            +IV L +   S+  L +VF
Sbjct: 198 RNIVRLHDVLHSERKLTLVF 139

 Score = 29.6 bits (65), Expect(2) = 4e-05,   Method: Composition-based stats.
 Identities = 10/26 (38%), Positives = 17/26 (65%)
 Frame = -1

Query: 115 EAVASHYMRQILEALRYCHDNNIIHR 140
           + ++SH+     E L +CH NN++HR
Sbjct: 79  QTLSSHFSTSY*EDLVFCHSNNVLHR 2
>01106
          Length = 878

 Score = 46.2 bits (108), Expect = 6e-05,   Method: Compositional matrix adjust.
 Identities = 44/156 (28%), Positives = 69/156 (44%), Gaps = 8/156 (5%)
 Frame = +3

Query: 7   LFEDVYELCEVIGKGPFSVVRRCINRETGQQFAVKIVDVAKFTSSPGLSTEDL---KREA 63
           LF   Y +   +G G FS V  C +    +  A+K+V  A+  +   L    L    RE+
Sbjct: 309 LFNGRYHVIRKLGWGHFSTVWLCWDLTCKRFVALKVVKSAQHYTETALDEVKLLKCVRES 488

Query: 64  SICHMLKHPHIVELLETYSSDGM----LYMVFEFMDGADLCFEIVKRADAGFVYSEAVAS 119
            +    +    V+LL+ +   G+    + MVFE + G +L   I++    G         
Sbjct: 489 DVADPAR-AKCVQLLDDFKISGVNGTHVAMVFEVL-GYNLLKLIIRSNYQGIPIHNV--K 656

Query: 120 HYMRQILEALRYCHDN-NIIHRDVKPHCVLLASKEN 154
             +RQ+LE L Y H    IIH D+KP  +L+   E 
Sbjct: 657 LIIRQVLEGLSYMHAKCRIIHTDIKPENILICVDET 764
>02638
          Length = 1490

 Score = 45.8 bits (107), Expect = 8e-05,   Method: Compositional matrix adjust.
 Identities = 32/101 (31%), Positives = 50/101 (49%), Gaps = 3/101 (2%)
 Frame = +1

Query: 177 GGRVGTPHFMAPEVVKREPYGKPVDVWGCGVILFILLSGCLPFYGTKE--RLFEGIIKGK 234
           G  +GT  FMAPEV++ E YG+  DVW  G ++ I +  C P + + +       I K  
Sbjct: 10  GQLLGTIAFMAPEVLRGESYGRACDVWSVGCVM-IEMCTCRPPWNSHDISNHLALIFKIA 186

Query: 235 YKMNPRQWS-HISESAKDLVRRMLMLDPAERITVYEALNHP 274
             ++P     ++S   +DL+ R L  D   R +  + L HP
Sbjct: 187 SSVDPPPIPENMSPPVRDLMLRCLEQDSDFRPSAKDLLMHP 309
>32957
          Length = 645

 Score = 45.8 bits (107), Expect = 8e-05,   Method: Composition-based stats.
 Identities = 22/44 (50%), Positives = 29/44 (65%), Gaps = 4/44 (9%)
 Frame = +3

Query: 176 AGGRV----GTPHFMAPEVVKREPYGKPVDVWGCGVILFILLSG 215
           +GGR     GT  +MAPEV +R+ YGK VD WG G++L  LL+ 
Sbjct: 24  SGGRTRTFCGTREYMAPEVHERKEYGKEVDWWGLGILLHELLAA 155
>21418
          Length = 831

 Score = 45.4 bits (106), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 17/51 (33%), Positives = 35/51 (68%)
 Frame = +2

Query: 230 IIKGKYKMNPRQWSHISESAKDLVRRMLMLDPAERITVYEALNHPWLKERD 280
           I  G+Y     +W+++S++AKDL++ ML +DP++R+ + + L + W+ + D
Sbjct: 14  IRSGQYDFPDPEWTNVSQAAKDLIKGMLNVDPSKRLCIEDVLRNKWIAQYD 166
>32000
          Length = 644

 Score = 44.7 bits (104), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 39/153 (25%), Positives = 64/153 (41%), Gaps = 26/153 (16%)
 Frame = -1

Query: 155 SAPVKLGGFGVAIQLGESGLVAGGRVGTPHFMAPEVVKR-EPYGKPVDVWGCGVILFILL 213
           +A +K+  FG+A   G         V T  + APE++     Y  PVD+W  G I   ++
Sbjct: 581 TAKMKIADFGLARVFGLPVRTYTHEVITLWYRAPEILLGCRFYSVPVDIWSLGCIFVEMM 402

Query: 214 SGCLPFYGTKE----------------RLFEGIIK-GKYKMNPRQWS--------HISES 248
           +    F G  E                +++ G+ K   YK    +W          +S+ 
Sbjct: 401 TRRALFPGDSEIDQLYRIFRTLGTPDEKVWPGVSKLPDYKPTFPKWPLKNLETVVSLSKV 222

Query: 249 AKDLVRRMLMLDPAERITVYEALNHPWLKERDR 281
             DL++RML  +P  RI+   A+ HP+  +  R
Sbjct: 221 GLDLLKRMLTYNPNRRISARSAMRHPYFNDMKR 123
>17722
          Length = 680

 Score = 44.7 bits (104), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 28/72 (38%), Positives = 41/72 (56%), Gaps = 1/72 (1%)
 Frame = -3

Query: 200 VDVWGCGVILFILLSGCLPFYGTK-ERLFEGIIKGKYKMNPRQWSHISESAKDLVRRMLM 258
           VD WG GV+++ ++ G LPFY    + LFE I+    K  PR   ++SE AK L+  +L 
Sbjct: 678 VDWWGTGVVMYEMMCGRLPFYNRDHDVLFELILLQNVKF-PR---NLSEEAKTLLSGLLA 511

Query: 259 LDPAERITVYEA 270
            +P  R+   EA
Sbjct: 510 KNPKRRLGGSEA 475
>12672
          Length = 773

 Score = 44.3 bits (103), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 31/109 (28%), Positives = 55/109 (50%), Gaps = 5/109 (4%)
 Frame = +3

Query: 122 MRQILEALRYCHDNNIIHRDVKPHCVLLASKENSAPVKLGGFGVAIQL--GESGLVAGGR 179
           ++     ++Y +DN  +HRD+K   +LL S+  +   K+G F   +    GE   V    
Sbjct: 9   VKGTASGIQYLNDNGHVHRDIKTANILLDSEYTA---KVGDFATVVSAPSGEGKTVQNAS 179

Query: 180 V--GTPHFMAPEVVKREPYGKPVDVWGCGVILFILLSGCLPF-YGTKER 225
           V  GT  ++APE +  +   K +D +  GV+L  +++G +   Y  +ER
Sbjct: 180 VVIGTAAYLAPEAIHFDVSTK-LDSYSFGVVLLEVITGLVAQDYSREER 323
>36481
          Length = 806

 Score = 44.3 bits (103), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 36/146 (24%), Positives = 65/146 (44%), Gaps = 5/146 (3%)
 Frame = +2

Query: 13  ELCEVIGKGPFSVVRRCINRETGQQFAVKIV-DVAKFTSSPGLSTEDLKREASICHMLKH 71
           +LC   G+G F  V +C +   G   A+KI+ +V K+  +  L    L++        K 
Sbjct: 371 KLCPHWGEGTFGKVVQCKDLLKGDDIALKIIKNVDKYREAAKLEINVLEKLRE-----KD 535

Query: 72  PH----IVELLETYSSDGMLYMVFEFMDGADLCFEIVKRADAGFVYSEAVASHYMRQILE 127
           PH     V++L+ +   G + + F  +  +   F+ +K    G  Y      H   Q+  
Sbjct: 536 PHAKHMCVQMLDWFDYHGHVCISFHMLGLS--VFDFLKDNSYG-AYPIEQVRHISYQLCY 706

Query: 128 ALRYCHDNNIIHRDVKPHCVLLASKE 153
           A+ + H+N + H D+KP  +L    +
Sbjct: 707 AVNFLHENQLTHTDLKPENILFVDSQ 784
>20655
          Length = 1181

 Score = 43.9 bits (102), Expect = 3e-04,   Method: Composition-based stats.
 Identities = 17/49 (34%), Positives = 30/49 (61%)
 Frame = +2

Query: 230 IIKGKYKMNPRQWSHISESAKDLVRRMLMLDPAERITVYEALNHPWLKE 278
           I  G+Y+    +WS +S+ AKDL+R ML  DP +R+ + + +   W+ +
Sbjct: 14  IRNGQYEFPKPEWSRVSQDAKDLIRGMLCTDPDKRLNIKQVMASKWVAD 160
>00715
          Length = 1788

 Score = 42.0 bits (97), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 44/183 (24%), Positives = 71/183 (38%), Gaps = 29/183 (15%)
 Frame = +1

Query: 69  LKHPHIVELLETYSSDGMLYMVFEFMDGADLCFEIVKRADAGFVYSE-------AVASHY 121
           L+H ++V +L   S       +  F DGA L  E V   +   + ++       ++    
Sbjct: 97  LRHVNVVSILGATS-------LHRFEDGAWLAMEYVGPLNLQTILNDHQQDIDSSMRLSL 255

Query: 122 MRQILEALRYCHDNNIIHRDVKPHCVLLASKENSAPVKLGGFGVAIQLGESGLVAGGR-- 179
             Q+   L Y H  NI+H D+KP   LL        +++  FG   QL  +GL  G R  
Sbjct: 256 ALQMARGLHYLHSINIVHLDLKPANCLLT---RDLKLRIADFGCCHQLTPTGLDMGEREG 426

Query: 180 --------------------VGTPHFMAPEVVKREPYGKPVDVWGCGVILFILLSGCLPF 219
                                GT  + APE++K        DV+  G+ L+ + +   P+
Sbjct: 427 GMAGNELELTPVQGAWKNELAGTLAYRAPELLKGLQPSVRSDVYSLGITLWQMCTRQGPY 606

Query: 220 YGT 222
            G 
Sbjct: 607 EGV 615
>18401
          Length = 463

 Score = 40.8 bits (94), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 36/139 (25%), Positives = 57/139 (41%), Gaps = 42/139 (30%)
 Frame = -3

Query: 180 VGTPHFMAPEVVKREPYGKPVDVWGCGVILFILLSGCLPF--YGTKERL--FEGII---- 231
           V T H+ APEV+    +  P DVW  G I+F L +G   F  +  KE L   E I+    
Sbjct: 449 VSTRHYRAPEVILELGWSHPCDVWSVGCIMFELYTGYTLFQTHDNKEHLAMMERILGSLP 270

Query: 232 --------KGKYKMNPR--------QWSHISESAK------------------DLVRRML 257
                   K KY  + R           ++ E+ K                  DL++++L
Sbjct: 269 YRMAKKTKKQKYFHHGRLDVPERSSMARYVRENTKPLLRYVKDRENKDHQQLFDLMKKLL 90

Query: 258 MLDPAERITVYEALNHPWL 276
             + + R ++ +AL HP+ 
Sbjct: 89  AYEASSRYSLLQALQHPFF 33
>14116
          Length = 1017

 Score = 40.8 bits (94), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 49/204 (24%), Positives = 83/204 (40%), Gaps = 5/204 (2%)
 Frame = -1

Query: 16  EVIGKGPFSVVRRCINRETGQQFAVKIVDVAKFTSSPG-LSTEDLKREASICHMLKHPHI 74
           E IGKG F  V+R       Q+  + +       ++P  +  +   +EA I     H ++
Sbjct: 618 EEIGKGNFGCVKRGFLTLPEQKGDILVAVKTLHNNNPREIELQSFLQEALIMKDFHHSNV 439

Query: 75  VELLE-TYSSDGMLYMVFEFMDGADLCFEIVKRADAGFVYSEAVASHYMRQILEALRYCH 133
           + L+    + D M  +V  FM   DL   I        +    +   Y   I   + Y  
Sbjct: 438 LTLIGICLNLDDMPLVVLPFMKHGDLLTYIRDDQHQPTIKDLIM---YGVDIARGMDYLA 268

Query: 134 DNNIIHRDVKPHCVLLASKENSAPVKLGGFGVAIQLGESGLVA--GGRVGTP-HFMAPEV 190
               +HRD+     +L   +    VK+  FG+A  + E    +    +   P  +MA E 
Sbjct: 267 GLKFVHRDLAARNCML---DEDFHVKVADFGLARDIYEKEYYSSENKKAKLPVKWMALES 97

Query: 191 VKREPYGKPVDVWGCGVILFILLS 214
           +++  Y    DVW  GV+L+ LL+
Sbjct: 96  LEKGNYDSKTDVWSYGVVLWELLT 25
>11185
          Length = 473

 Score = 40.0 bits (92), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 28/115 (24%), Positives = 45/115 (39%), Gaps = 22/115 (19%)
 Frame = +1

Query: 124 QILEALRYCHDNNIIHRDVKPHCVLLASKENSAPVKLGGFGVA----------------- 166
            ++  L Y H   I+  D++P  VLL   + S  +K   FG++                 
Sbjct: 25  HLVTGLHYIHSLGILFHDLRPSKVLL---DTSGVLKFADFGLSKVEGENLEELFFKFAEA 195

Query: 167 -----IQLGESGLVAGGRVGTPHFMAPEVVKREPYGKPVDVWGCGVILFILLSGC 216
                IQ  E  +      G+P +MAPEV +        D+W  G + + + SG 
Sbjct: 196 GDQWNIQSAEEMMKQVPTSGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFSGS 360
>07940
          Length = 1336

 Score = 39.7 bits (91), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 30/103 (29%), Positives = 45/103 (43%), Gaps = 4/103 (3%)
 Frame = -3

Query: 121 YMRQILEALRYCHDNNIIHRDVKPHCVLLASKENSAPVKLGGFGVAIQLGESGL---VAG 177
           Y  Q+   + Y      IHRD+    VL+A +     +K+  FG+   L +         
Sbjct: 332 YAYQVARGMEYLASKQCIHRDLAARNVLVAEE---YVLKIADFGLTRNLQQFDYYRKTTD 162

Query: 178 GRVGTPHFMAPEVVKREPYGKPVDVWGCGVILF-ILLSGCLPF 219
           GR+    +MAPE +    Y    DVW  GV+L+ I   G  P+
Sbjct: 161 GRLPV-KWMAPEALFDRKYTSKSDVWSYGVLLWEIFTLGGNPY 36
>18287
          Length = 678

 Score = 38.9 bits (89), Expect = 0.011,   Method: Compositional matrix adjust.
 Identities = 19/44 (43%), Positives = 28/44 (63%)
 Frame = -3

Query: 235 YKMNPRQWSHISESAKDLVRRMLMLDPAERITVYEALNHPWLKE 278
           Y ++P    H +  A  L+ RML+L+P  RI+  EAL+HP+L E
Sbjct: 457 YNLSP----HATHEAVRLLTRMLILNPKNRISAEEALSHPYLDE 338
>07291
          Length = 833

 Score = 38.5 bits (88), Expect = 0.011,   Method: Compositional matrix adjust.
 Identities = 30/129 (23%), Positives = 57/129 (44%), Gaps = 8/129 (6%)
 Frame = +1

Query: 121 YMRQILEALRYCHDNNIIHRDVKP-HCVLLASKENSAPVKLGGFGVAIQLGESGLVAGGR 179
           + RQI + + Y  +  ++HR++   +C++         ++L  +GV   L          
Sbjct: 64  FGRQIADGMAYLQEVKVVHRNLAARNCIVTEDGR----LQLSDYGVTGSLFPQSYYTAD- 228

Query: 180 VGTP-----HFMAPEVVKREPYGKPVDVWGCGVILFILLS-GCLPFYGTKERLFEGIIKG 233
             +P      +MAPE +    +    DVW  GV+L+ LL+ G  P+   +       +K 
Sbjct: 229 -DSPARDLVKWMAPETIDNFHFSSKSDVWAFGVVLWELLTRGITPYPDVENSSLLPYLKE 405

Query: 234 KYKM-NPRQ 241
            ++M  P+Q
Sbjct: 406 GHRMKKPKQ 432
>19301
          Length = 712

 Score = 38.5 bits (88), Expect = 0.011,   Method: Compositional matrix adjust.
 Identities = 41/164 (25%), Positives = 73/164 (44%)
 Frame = +2

Query: 3   DDDVLFEDVYELCEVIGKGPFSVVRRCINRETGQQFAVKIVDVAKFTSSPGLSTEDLKRE 62
           D ++ FE + +L E +G G    V   + +   ++ AVK V   K T        +L++ 
Sbjct: 287 DWEIPFESITDL-EWLGSGAQGAVF--LGKLCAEEVAVKKVRDIKETD-----IRNLRK- 439

Query: 63  ASICHMLKHPHIVELLETYSSDGMLYMVFEFMDGADLCFEIVKRADAGFVYSEAVASHYM 122
                 L HP+I+      +      ++ E+     L +E+++    G     A+   + 
Sbjct: 440 ------LNHPNIISFKGVCTQAPCYCIIMEYCPYGQL-YEVLRD---GKEIPPALVLDWS 589

Query: 123 RQILEALRYCHDNNIIHRDVKPHCVLLASKENSAPVKLGGFGVA 166
           +QI   + Y H + IIHRD+K   VL+A  +    VK+  FG +
Sbjct: 590 KQIASGMNYLHSHKIIHRDLKSPNVLVAKND---VVKISDFGTS 712
>21800
          Length = 855

 Score = 38.5 bits (88), Expect = 0.011,   Method: Compositional matrix adjust.
 Identities = 28/85 (32%), Positives = 43/85 (50%), Gaps = 5/85 (5%)
 Frame = +2

Query: 75  VELLETYSSDGM----LYMVFEFMDGADLCFEIVKRADAGFVYSEAVASHYMRQILEALR 130
           V+LL+ +   G+    + MVFE + G +L   I++    G           +RQ+LE L 
Sbjct: 506 VQLLDDFKISGVNGTHVCMVFEVL-GYNLLKLIIRSNYQGIPVHNV--KLIIRQVLEGLN 676

Query: 131 YCHDN-NIIHRDVKPHCVLLASKEN 154
           Y H   NIIH D+KP  +L+   +N
Sbjct: 677 YLHAKCNIIHTDIKPENILICVDDN 751
>11404
          Length = 563

 Score = 38.1 bits (87), Expect = 0.016,   Method: Compositional matrix adjust.
 Identities = 39/150 (26%), Positives = 71/150 (47%), Gaps = 8/150 (5%)
 Frame = +1

Query: 10  DVYELCEVIGKGPFSVVRRCINRETGQQFAVKIVDVAKFTSSPGLSTEDLKREASICHML 69
           D YE+  +IGKG F  V +  +    +Q A+KI+   K    P L+   +  E  +  M+
Sbjct: 139 DRYEIDSLIGKGSFGQVVKAYDHTDNEQVAIKIIKNKK----PFLNQAQI--EVKLLEMM 300

Query: 70  -KHP-----HIVELLETYSSDGMLYMVFEFMDGADLCFEIVKRADAGFVYSEAVASHYMR 123
            +H      +IV L   +     L +VFE +      +++++  +   V S  +   + +
Sbjct: 301 NRHDTDNKYYIVRLKRHFMFRSHLCLVFELLSYN--LYDLLRNTNFRGV-SLNLTRKFAQ 471

Query: 124 QILEALRYCH--DNNIIHRDVKPHCVLLAS 151
           Q+  AL +    + +IIH D+KP  +LL +
Sbjct: 472 QLCTALLFLATPEMSIIHCDLKPENILLCN 561
>20073
          Length = 582

 Score = 37.7 bits (86), Expect = 0.020,   Method: Composition-based stats.
 Identities = 19/60 (31%), Positives = 36/60 (60%)
 Frame = +3

Query: 509 VARIMHGGMIHRQGTLHVGDEIREINGISVANQTVEQLQKMLREMRGSITFKIVPSYRTQ 568
           ++RI+ GG+  R   L  GD++  +NG+SV  +  E+  ++L+  +GS+  ++V  Y  Q
Sbjct: 54  ISRIIPGGVADRLNCLKRGDQLLSVNGVSVEGEYHEKAVELLKLAQGSV--RLVVRYTPQ 227
>25019
          Length = 730

 Score = 36.6 bits (83), Expect = 0.047,   Method: Composition-based stats.
 Identities = 19/49 (38%), Positives = 25/49 (51%)
 Frame = +3

Query: 158 VKLGGFGVAIQLGESGLVAGGRVGTPHFMAPEVVKREPYGKPVDVWGCG 206
           VKL  FG+  +      V     GT  +MAPE++ R  +GK VD W  G
Sbjct: 291 VKLTDFGLCKEAITGTRVTHTFCGTIEYMAPEILTRTGHGKAVDWWSLG 437
>16350
          Length = 1108

 Score = 36.2 bits (82), Expect = 0.054,   Method: Compositional matrix adjust.
 Identities = 16/48 (33%), Positives = 28/48 (58%)
 Frame = +3

Query: 230 IIKGKYKMNPRQWSHISESAKDLVRRMLMLDPAERITVYEALNHPWLK 277
           ++  KY+ +P+     +++  D +  ML  DP +R T  ++L HPWLK
Sbjct: 711 VLVEKYEWDPKD----AKAFADFLAPMLEFDPEQRATAAQSLQHPWLK 842
>00638
          Length = 1595

 Score = 36.2 bits (82), Expect = 0.063,   Method: Compositional matrix adjust.
 Identities = 18/49 (36%), Positives = 28/49 (57%), Gaps = 3/49 (6%)
 Frame = +2

Query: 99  LCFEIVKRADAGFVY---SEAVASHYMRQILEALRYCHDNNIIHRDVKP 144
           L FE V   D   +Y   ++     Y+ ++++AL +CH   I+HRDVKP
Sbjct: 356 LIFEHVNNTDFKQLYQTFTDYDIRFYLYELMKALDFCHSMGIMHRDVKP 502
>26154
          Length = 446

 Score = 36.2 bits (82), Expect = 0.065,   Method: Composition-based stats.
 Identities = 17/60 (28%), Positives = 31/60 (51%), Gaps = 2/60 (3%)
 Frame = -3

Query: 494 PMGITLKMNE--LNHCIVARIMHGGMIHRQGTLHVGDEIREINGISVANQTVEQLQKMLR 551
           P+GIT+   E  L++ +++ +  GG+  + G +HVGD +  IN  +       +L    R
Sbjct: 198 PLGITISGTEDPLDNIVISELTAGGLAQKTGAMHVGDRLLGINESTTKTSPCRKLSACCR 19
>20513
          Length = 405

 Score = 35.8 bits (81), Expect = 0.071,   Method: Compositional matrix adjust.
 Identities = 16/48 (33%), Positives = 28/48 (58%)
 Frame = -1

Query: 230 IIKGKYKMNPRQWSHISESAKDLVRRMLMLDPAERITVYEALNHPWLK 277
           ++  KY+ +P+     +++  D +  ML  DP +R T  ++L HPWLK
Sbjct: 333 VLVEKYEWDPKD----AKAFADFLAPMLEFDPEQRATAAQSLQHPWLK 202
>07833
          Length = 1504

 Score = 35.4 bits (80), Expect = 0.092,   Method: Compositional matrix adjust.
 Identities = 31/172 (18%), Positives = 71/172 (41%), Gaps = 8/172 (4%)
 Frame = -3

Query: 56   TEDLKREASICHMLKHPHIVELLETYSSDGMLYMVFEFMDGADLCFEIVKRADAGFVYSE 115
            T D   E     +  HP+++ +L   +    L ++ +FM    L   +    ++G V  +
Sbjct: 1487 TRDFMEEFPRLRIFNHPNVLPVLACCNQPPNLVLISQFMPFGSLYNTL--HGESGIVVDQ 1314

Query: 116  AVASHYMRQILEALRYCHDNNIIHRDVKPHCVL-----LASKENSAPVKLGGFGVAIQLG 170
              +  +   I   + + H          P+ +L     +  ++ +A + +  +  +    
Sbjct: 1313 NQSLRFAMDIARGMEFLHS----MEPTIPNFLLTSKHVMIDEDLTARINMADYCFSFH-- 1152

Query: 171  ESGLVAGGRVGTPHFMAPEVVKREP---YGKPVDVWGCGVILFILLSGCLPF 219
                   G+V +P +MAPE ++R P     +  D+W   ++++ L +  +PF
Sbjct: 1151 -----EKGKVYSPAWMAPEALQRRPDDINTRAADMWSFAILMWELETREVPF 1011
>26009
          Length = 886

 Score = 35.4 bits (80), Expect = 0.095,   Method: Composition-based stats.
 Identities = 14/38 (36%), Positives = 24/38 (63%)
 Frame = +3

Query: 118 ASHYMRQILEALRYCHDNNIIHRDVKPHCVLLASKENS 155
           A   M+Q++ AL + H   ++HRD+KP  VL+ + + S
Sbjct: 717 AKSVMKQLVSALDFMHSKQLVHRDIKPENVLILTPDFS 830
>31489
          Length = 329

 Score = 35.4 bits (80), Expect = 0.12,   Method: Compositional matrix adjust.
 Identities = 14/35 (40%), Positives = 23/35 (65%)
 Frame = +3

Query: 114 SEAVASHYMRQILEALRYCHDNNIIHRDVKPHCVL 148
           +E    +++ QIL  L+Y H  N++HRD+KP  +L
Sbjct: 159 TEEHIRYFLYQILRGLKYIHSANVVHRDLKPSNLL 263
>17286
          Length = 489

 Score = 35.0 bits (79), Expect = 0.13,   Method: Compositional matrix adjust.
 Identities = 21/65 (32%), Positives = 31/65 (47%)
 Frame = +3

Query: 580 QPKGRQIYVRAQFEYDPAKDDLIPCKEAGIRFRVGDIIQIISKDDHNWWQGKLENSKNGT 639
           QP  R IY            D +P  +  + F+ GD+I +IS+ D NW++G    S +G 
Sbjct: 21  QPCARAIY------------DFLPESDGELGFQEGDMITLISQVDENWFEG----SVHGK 152

Query: 640 AGLIP 644
            G  P
Sbjct: 153 VGYFP 167
>22005
          Length = 873

 Score = 35.0 bits (79), Expect = 0.15,   Method: Composition-based stats.
 Identities = 17/42 (40%), Positives = 25/42 (59%)
 Frame = +1

Query: 58  DLKREASICHMLKHPHIVELLETYSSDGMLYMVFEFMDGADL 99
           D +REAS+     HP+IV+LL   +    + ++FEFM   DL
Sbjct: 148 DFEREASLMADFDHPNIVKLLGVCAIGKPMCLLFEFMSKGDL 273
>28157
          Length = 400

 Score = 35.0 bits (79), Expect = 0.15,   Method: Compositional matrix adjust.
 Identities = 28/104 (26%), Positives = 50/104 (48%), Gaps = 3/104 (2%)
 Frame = +3

Query: 69  LKHPHIVELLETYSSDGMLYMVFEFMDGADLCFEIVKRADAGFVYSEAVASHYMRQILEA 128
           + HP+IV L      D  + +V E+ +G  L + ++  +     Y+ A A +++ Q    
Sbjct: 81  VSHPNIVCLYGA-CRDHPVCLVMEYAEGGSL-YNVLHGSGPQPQYTAAHAMNWLLQCALG 254

Query: 129 LRYCHD---NNIIHRDVKPHCVLLASKENSAPVKLGGFGVAIQL 169
           + Y H      +IHRD+KP  +LL   +    +K+  FG A  +
Sbjct: 255 VEYLHGMKPKALIHRDLKPPNLLLI--QCGTKLKICDFGTACDI 380
>23319
          Length = 2235

 Score = 34.7 bits (78), Expect = 0.17,   Method: Compositional matrix adjust.
 Identities = 26/118 (22%), Positives = 51/118 (43%), Gaps = 27/118 (22%)
 Frame = +3

Query: 188 PEVVKREPYGKPVDVWGCGVILFILLSGCLPFYGTKE------RLFE-----------GI 230
           P+V   + Y   +D+W  G I   L +   P +   +      R+F+           G+
Sbjct: 3   PDVYXAKMYSTSIDMWSAGCIFAELANAGRPLFPGNDDDDQLKRIFKLLGTPTEDQWPGM 182

Query: 231 IK-GKYKMNP-----RQWSHI----SESAKDLVRRMLMLDPAERITVYEALNHPWLKE 278
            +   Y+M P       W  +    +   +DL++ +L+  P++R++  EAL HP+  +
Sbjct: 183 TQLPNYRMFPMYHVTTTWQQVVPKLNSKGRDLLQCLLVCCPSDRMSADEALQHPYFAD 356
>17253
          Length = 483

 Score = 34.3 bits (77), Expect = 0.21,   Method: Composition-based stats.
 Identities = 33/144 (22%), Positives = 60/144 (41%), Gaps = 9/144 (6%)
 Frame = -1

Query: 61  REASICHML-KHPHIVELLETYSSDGMLYMVFEFMDGADLCFEIVKRADAGFVYSEAVAS 119
           RE SI   L +HP++V  +   +      ++ EF    DL   + KR     V+  + A+
Sbjct: 402 RELSIMRKLPRHPNVVSFMGCCTMSDPALILMEFCCHGDLLSFLRKRRPDRTVFLTSTAN 223

Query: 120 --------HYMRQILEALRYCHDNNIIHRDVKPHCVLLASKENSAPVKLGGFGVAIQLGE 171
                    +   +   + +  +N I+HRDV    VL++ +      K+  FG++ ++G+
Sbjct: 222 DLTARDFFSFALHVARGMAHVANNKIVHRDVAARNVLISERN---VCKVSDFGLSRRVGD 52

Query: 172 SGLVAGGRVGTPHFMAPEVVKREP 195
              V             E+V R P
Sbjct: 51  QNDVY------------EIVSRRP 16
>30740
          Length = 488

 Score = 34.3 bits (77), Expect = 0.23,   Method: Compositional matrix adjust.
 Identities = 33/148 (22%), Positives = 56/148 (37%), Gaps = 1/148 (0%)
 Frame = +2

Query: 502 NELNHCIVARIMHGGMIHRQGTLHVGDEIREINGI-SVANQTVEQLQKMLREMRGSITFK 560
           ++++H I+ RI  GG+        +GD  +E N I S+ N            +R +   K
Sbjct: 29  SKVSHYIINRIQVGGLTR----FKIGD--KEFNDIPSLLNFYKSHYLDTTTLIRPAPREK 190

Query: 561 IVPSYRTQSSSCEDLPSTTQPKGRQIYVRAQFEYDPAKDDLIPCKEAGIRFRVGDIIQII 620
           ++  Y       EDLP                                  F  GDI+++I
Sbjct: 191 LMGKYDFSGRDPEDLP----------------------------------FSKGDILELI 268

Query: 621 SKDDHNWWQGKLENSKNGTAGLIPSPEL 648
           SKD+  WW  + ++ + G   L  +P +
Sbjct: 269 SKDEEEWWTARDKHGRVGQDPLSSTPHV 352
>37063
          Length = 455

 Score = 34.3 bits (77), Expect = 0.25,   Method: Composition-based stats.
 Identities = 26/87 (29%), Positives = 40/87 (45%), Gaps = 15/87 (17%)
 Frame = -2

Query: 142 VKPHCVLLASKENSAPVKLGGFGVAIQLGESGLVAGGR----------VGTPHFMAPEVV 191
           +KP  +L    +   P+K+  F +A     SG+   G           VG+  +MAPEVV
Sbjct: 454 LKPENILCEHLDEVVPLKICDFDLA-----SGINCDGDGTKTPELLTPVGSAEYMAPEVV 290

Query: 192 -----KREPYGKPVDVWGCGVILFILL 213
                +   Y K  D+W  G+IL +L+
Sbjct: 289 DAWVGESFSYDKRCDMWSLGIIL*VLV 209
>13664
          Length = 507

 Score = 34.3 bits (77), Expect = 0.25,   Method: Composition-based stats.
 Identities = 21/73 (28%), Positives = 34/73 (46%)
 Frame = +2

Query: 566 RTQSSSCEDLPSTTQPKGRQIYVRAQFEYDPAKDDLIPCKEAGIRFRVGDIIQIISKDDH 625
           + Q S    L ST +PK     V A ++Y   + D        +    GD+I ++ KD  
Sbjct: 317 KAQFSFQSPLGSTRKPKK----VVALYDYKAQRSD-------ELTILSGDVIMLLHKDSE 463

Query: 626 NWWQGKLENSKNG 638
           +WW G+L + + G
Sbjct: 464 SWWMGELLDGQQG 502
>14104
          Length = 573

 Score = 33.9 bits (76), Expect = 0.30,   Method: Compositional matrix adjust.
 Identities = 12/36 (33%), Positives = 24/36 (66%)
 Frame = +1

Query: 241 QWSHISESAKDLVRRMLMLDPAERITVYEALNHPWL 276
           ++S+ +  A   ++  L +DPAER+T ++ L HP++
Sbjct: 76  KFSNAAPQAMSFMQSCLKMDPAERLTCHQLLQHPYM 183
>32405
          Length = 343

 Score = 33.5 bits (75), Expect = 0.40,   Method: Composition-based stats.
 Identities = 13/39 (33%), Positives = 22/39 (56%)
 Frame = +2

Query: 625 HNWWQGKLENSKNGTAGLIPSPELQEWRVACIAMEKTKQ 663
           HN+WQ +    KNG   L  S ++   + +C  M++TK+
Sbjct: 23  HNFWQARDRGEKNGMLSLKTSSQMLYLQTSCCDMKRTKK 139
>35032
          Length = 465

 Score = 33.5 bits (75), Expect = 0.44,   Method: Composition-based stats.
 Identities = 14/26 (53%), Positives = 20/26 (76%)
 Frame = +3

Query: 251 DLVRRMLMLDPAERITVYEALNHPWL 276
           DLV+R+L  DP++R+T   AL HP+L
Sbjct: 147 DLVKRLLNYDPSKRLTPXXALAHPFL 224
>18996
          Length = 491

 Score = 33.1 bits (74), Expect = 0.53,   Method: Compositional matrix adjust.
 Identities = 23/79 (29%), Positives = 37/79 (46%), Gaps = 2/79 (2%)
 Frame = +2

Query: 138 IHRDVKPHCVLLASKENSAPVKLGGFGVAIQLGESGLVAG-GRVGTP-HFMAPEVVKREP 195
           IHRD+    +L+    + + VK+  FG+A      G   G  +   P  + +PE ++   
Sbjct: 2   IHRDLAARNILV----DRSCVKISDFGLAQFANADGYYYGISQRDIPIKWYSPEAIETCK 169

Query: 196 YGKPVDVWGCGVILFILLS 214
           +    DVW  GV LF + S
Sbjct: 170 FSSYSDVWSYGVTLFEMFS 226
>22098
          Length = 1090

 Score = 32.7 bits (73), Expect = 0.64,   Method: Compositional matrix adjust.
 Identities = 16/45 (35%), Positives = 30/45 (66%), Gaps = 6/45 (13%)
 Frame = +2

Query: 178 GRVGTPHFMAPEVVK------REPYGKPVDVWGCGVILFILLSGC 216
           G VGT  +MAPEV++      R+ + + +D++ CG++L+ L++ C
Sbjct: 11  GLVGTRRYMAPEVLEGAICFNRDSFLR-IDMYACGLVLWELMTRC 142
>17516
          Length = 453

 Score = 32.7 bits (73), Expect = 0.64,   Method: Composition-based stats.
 Identities = 17/42 (40%), Positives = 25/42 (59%), Gaps = 1/42 (2%)
 Frame = -3

Query: 175 VAGGRVGTPHFMAPEV-VKREPYGKPVDVWGCGVILFILLSG 215
           +AG   GTP +MAPEV +++  Y    DV+   +IL+ L  G
Sbjct: 451 IAGTLAGTPVYMAPEVLLQKGQYDMKADVYSLAIILWELWYG 326
>00341
          Length = 1915

 Score = 31.6 bits (70), Expect = 1.4,   Method: Compositional matrix adjust.
 Identities = 19/71 (26%), Positives = 31/71 (43%)
 Frame = -1

Query: 575  LPSTTQPKGRQIYVRAQFEYDPAKDDLIPCKEAGIRFRVGDIIQIISKDDHNWWQGKLEN 634
            L S     GR+  V   ++YDP K      +   + F  GDI+ +  +   +   G    
Sbjct: 1888 LNSIQYKTGRKRTVMGLYDYDPEKQSPGDYRACELAFHAGDILLVYGEARQD---GFYHG 1718

Query: 635  SKNGTAGLIPS 645
             +NG  GL+P+
Sbjct: 1717 ERNGQRGLVPA 1685
>20640
          Length = 1492

 Score = 31.6 bits (70), Expect = 1.4,   Method: Compositional matrix adjust.
 Identities = 28/108 (25%), Positives = 47/108 (43%), Gaps = 4/108 (3%)
 Frame = +1

Query: 138 IHRDVKPHCVLLASKENSAPVKLGGFGVAIQLGESGLVAGGRV-GTP-HFMAPEVVKREP 195
           +HRD+     L+    +   VK+  FG+A  +       G      P  +M  E +    
Sbjct: 10  VHRDLATRNCLVG---HDLVVKISDFGLARSVHSVDYYRGSEHDAIPIRWMPLEAILYNK 180

Query: 196 YGKPVDVWGCGVILFILLSGCL-PFYG-TKERLFEGIIKGKYKMNPRQ 241
           +    DVW  GV+L+ + +  L P+YG T E +   + +GK    P +
Sbjct: 181 FSTQSDVWSFGVVLWEIFAFALQPYYGLTHEEVVRFVKEGKVLACPER 324
>20160
          Length = 1277

 Score = 31.6 bits (70), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 15/42 (35%), Positives = 23/42 (54%)
 Frame = +2

Query: 247 ESAKDLVRRMLMLDPAERITVYEALNHPWLKERDRYAYKIHL 288
           E A DL+ R + LDP+ R  + + L H W+ +     Y+ HL
Sbjct: 332 EDAADLINRCIALDPSTRPVLADILKHKWMTK----DYEYHL 445
>16716
          Length = 934

 Score = 30.8 bits (68), Expect = 2.3,   Method: Compositional matrix adjust.
 Identities = 22/70 (31%), Positives = 32/70 (45%)
 Frame = -1

Query: 576 PSTTQPKGRQIYVRAQFEYDPAKDDLIPCKEAGIRFRVGDIIQIISKDDHNWWQGKLENS 635
           P+ +QP G    + A ++Y  A DD +        F   D+I  I   D  WW+G    S
Sbjct: 496 PAQSQPGGGSTAI-ALYDYQAADDDEL-------TFDPDDVITDIEMIDDGWWRG----S 353

Query: 636 KNGTAGLIPS 645
            +G  GL P+
Sbjct: 352 CHGKNGLFPA 323
>20773
          Length = 391

 Score = 30.8 bits (68), Expect = 2.4,   Method: Composition-based stats.
 Identities = 12/32 (37%), Positives = 24/32 (75%)
 Frame = -1

Query: 245 ISESAKDLVRRMLMLDPAERITVYEALNHPWL 276
           +++   +LV+R+L  DP++R+T   AL+HP++
Sbjct: 322 VTQHFYNLVQRLLTYDPSQRLTPDLALSHPFV 227
>12762
          Length = 900

 Score = 30.8 bits (68), Expect = 2.4,   Method: Composition-based stats.
 Identities = 11/29 (37%), Positives = 20/29 (68%)
 Frame = -3

Query: 137 IIHRDVKPHCVLLASKENSAPVKLGGFGV 165
           ++H+++ PH + L +K +S  + LGG GV
Sbjct: 736 VLHQNIHPHVIPLGAKLHSTAISLGGRGV 650
>15549
          Length = 470

 Score = 30.4 bits (67), Expect = 3.2,   Method: Compositional matrix adjust.
 Identities = 14/34 (41%), Positives = 21/34 (61%)
 Frame = -1

Query: 8   FEDVYELCEVIGKGPFSVVRRCINRETGQQFAVK 41
           F D +E  E +GKG + +V R  N+   Q++AVK
Sbjct: 224 FADEFECIEQMGKGGYGIVFRAKNKVDEQEYAVK 123
>17644
          Length = 463

 Score = 30.0 bits (66), Expect = 4.1,   Method: Compositional matrix adjust.
 Identities = 12/32 (37%), Positives = 23/32 (71%)
 Frame = +3

Query: 245 ISESAKDLVRRMLMLDPAERITVYEALNHPWL 276
           +++   BLV+R+L  DP++R+T   AL+HP++
Sbjct: 69  VTQHFYBLVQRLLTYDPSQRLTPDLALSHPFV 164
>20131
          Length = 574

 Score = 30.0 bits (66), Expect = 4.4,   Method: Compositional matrix adjust.
 Identities = 18/57 (31%), Positives = 27/57 (47%)
 Frame = -2

Query: 589 RAQFEYDPAKDDLIPCKEAGIRFRVGDIIQIISKDDHNWWQGKLENSKNGTAGLIPS 645
           R + EY  A    +  + A + F  GD+I +  KD+ +WW G L        G+ PS
Sbjct: 492 RKEGEYYVAMYSYVSGETADLTFNEGDMILVTKKDE-DWWTGTLGEK----TGMFPS 337
>03294
          Length = 1684

 Score = 29.3 bits (64), Expect = 6.7,   Method: Compositional matrix adjust.
 Identities = 30/117 (25%), Positives = 43/117 (36%), Gaps = 26/117 (22%)
 Frame = -1

Query: 199  PVDVWGCGVILFILLSGCLPFYGTKE-----RLFEGIIKGKYKMNPR------------Q 241
            PVDVW  G I   +L     F G  E     ++F  I     +  P              
Sbjct: 1675 PVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIFRIIGTPTEQTWPEFHKLPAFNGMFPL 1496

Query: 242  WSH--ISESAKDL-------VRRMLMLDPAERITVYEALNHPWLKERDRYAYKIHLP 289
            W    +SE+  DL       + R L  DPA+RI+  + L H +    D     + +P
Sbjct: 1495 WKEGKLSETLTDLDSLGLDLIERTLKCDPAQRISCKKMLQHAYFLNVDTSVKPVDVP 1325
>26032
          Length = 465

 Score = 29.3 bits (64), Expect = 6.8,   Method: Compositional matrix adjust.
 Identities = 15/37 (40%), Positives = 21/37 (56%)
 Frame = +2

Query: 609 IRFRVGDIIQIISKDDHNWWQGKLENSKNGTAGLIPS 645
           + FR  DII +IS+ D + W G+L    NG  G  P+
Sbjct: 56  LGFRKNDIITLISQKDEHCWIGEL----NGLRGWFPA 154
>17300
          Length = 480

 Score = 29.3 bits (64), Expect = 7.3,   Method: Composition-based stats.
 Identities = 25/108 (23%), Positives = 51/108 (47%), Gaps = 8/108 (7%)
 Frame = +1

Query: 134 DNNIIHRDVKPHCVLLASKENSAPV-KLGGFGVAIQLGESGL-----VAGGRVGTPHFMA 187
           D   +HRD+    +L+    N   V K+  FG++ ++            GG++    + A
Sbjct: 28  DMGYVHRDLAARNILV----NEILVCKVADFGLSREIESDTTEGAYTTKGGKIPV-RWTA 192

Query: 188 PEVVKREPYGKPVDVWGCGVILFILLS-GCLPFYG-TKERLFEGIIKG 233
           PE +    +    DVW  GV+++ ++S G  P++  + + + + + KG
Sbjct: 193 PEAIAYRKFTSASDVWSFGVVMWEVMSYGERPYWNWSNQDVIKAVEKG 336
>33586
          Length = 551

 Score = 29.3 bits (64), Expect = 7.6,   Method: Composition-based stats.
 Identities = 14/52 (26%), Positives = 27/52 (51%)
 Frame = +2

Query: 74  IVELLETYSSDGMLYMVFEFMDGADLCFEIVKRADAGFVYSEAVASHYMRQI 125
           IV L   + ++G LY++ EF+ G DL   + K      +++E     Y+ ++
Sbjct: 407 IVHLHYAFQTEGKLYLILEFLRGGDLFTRLSKEV----MFTEEDVKFYLAEL 550
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31982030|ref|NP_598557.3| Rho GDP dissociation
inhibitor (GDI) alpha [Mus musculus]
         (204 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

15450                                                                 181   1e-46
19447                                                                 167   3e-42
29242                                                                  52   2e-07
30027                                                                  29   1.1  
09993                                                                  28   1.8  
28038                                                                  27   8.1  
>15450
          Length = 690

 Score =  181 bits (460), Expect = 1e-46,   Method: Compositional matrix adjust.
 Identities = 91/181 (50%), Positives = 128/181 (70%), Gaps = 5/181 (2%)
 Frame = +1

Query: 27  YKPPAQKSIQEIQELDKDDESLRKYKEALL-----GRVAVSADPNVPNVIVTRLTLVCST 81
           Y+PPA KS+ EI + D++DESLRKYKE LL     G   +  D N  NVIV +L  +C  
Sbjct: 61  YRPPAPKSLDEILKQDQEDESLRKYKEQLLADAGAGEKIILDDSNPLNVIVKKLA-ICVE 237

Query: 82  APGPLELDLTGDLESFKKQSFVLKEGVEYRIKISFRVNREIVSGMKYIQHTYRKGVKIDK 141
               +E+DLT   E  K++  VLK+G +YR+KI F V R+IVSG++Y Q  YRKG+++DK
Sbjct: 238 DRADMEIDLTLPKEKIKEKKIVLKDGCKYRVKIFFNVQRDIVSGLRYEQKVYRKGIRVDK 417

Query: 142 TDYMVGSYGPRAEEYEFLTPMEEAPKGMLARGSYNIKSRFTDDDKTDHLSWEWNLTIKKE 201
            ++MVGSY P+ EE+ ++TP ++AP GM+ RG Y ++SRFTDDDK  +L WEW+L+IKK+
Sbjct: 418 GNFMVGSYAPKKEEHSYMTPPDDAPSGMVCRGDYKVESRFTDDDKHVYLDWEWSLSIKKD 597

Query: 202 W 202
           +
Sbjct: 598 F 600
>19447
          Length = 2016

 Score =  167 bits (423), Expect = 3e-42,   Method: Compositional matrix adjust.
 Identities = 93/204 (45%), Positives = 122/204 (59%), Gaps = 3/204 (1%)
 Frame = +1

Query: 2   AEQEP-TAEQLAQIAAENEEDEHSVNYKPPAQKSIQEIQELDKDDESLRKYKEALLGRV- 59
           AEQ P  AE +A    +N        YK P QKSI+EI   D++DESL+KYKE LLG   
Sbjct: 43  AEQNPEVAEAIADDDDDNG------TYKAPPQKSIEEIIAADEEDESLKKYKETLLGATK 204

Query: 60  -AVSADPNVPNVIVTRLTLVCSTAPGPLELDLTGDLESFKKQSFVLKEGVEYRIKISFRV 118
             +  D    NVIV +L +         E+DLT  L+  K+   V KEG +Y IK+ F V
Sbjct: 205 DTIVIDETKKNVIVKKLIIYFDEDRSS-EIDLTLPLDKIKETKVVFKEGCQYTIKLFFNV 381

Query: 119 NREIVSGMKYIQHTYRKGVKIDKTDYMVGSYGPRAEEYEFLTPMEEAPKGMLARGSYNIK 178
            R+IVSG+ Y  +  RKG K+DK   MVGSYGP  +E+ + +P +EAPKGM++RG Y + 
Sbjct: 382 QRDIVSGLHYSHYVTRKGFKVDKMSNMVGSYGPSLKEHLYTSPPDEAPKGMMSRGEYKVH 561

Query: 179 SRFTDDDKTDHLSWEWNLTIKKEW 202
           S+F DDDK  +L W W   IKK+W
Sbjct: 562 SKFCDDDKNVYLEWVWIFEIKKDW 633
>29242
          Length = 316

 Score = 52.0 bits (123), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 25/51 (49%), Positives = 35/51 (68%), Gaps = 3/51 (5%)
 Frame = -1

Query: 19  EEDEHSVNYKPPAQKSIQEIQELDKDDESLRKYKEALLGRV---AVSADPN 66
           +ED H  NY+ P +K+I+E+   D++DESLR+YKEALLG      +  DPN
Sbjct: 169 DEDVHDANYQAPPEKTIEELMAADQEDESLRRYKEALLGAAQSETIIVDPN 17
>30027
          Length = 343

 Score = 29.3 bits (64), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 15/37 (40%), Positives = 21/37 (56%)
 Frame = -1

Query: 141 KTDYMVGSYGPRAEEYEFLTPMEEAPKGMLARGSYNI 177
           K +Y+   YGP   E  +L   + APK ML + S+NI
Sbjct: 136 KINYLR*CYGPSEIEASYLPSCK*APKLML*KSSFNI 26
>09993
          Length = 2380

 Score = 28.5 bits (62), Expect = 1.8,   Method: Compositional matrix adjust.
 Identities = 17/45 (37%), Positives = 25/45 (55%)
 Frame = +3

Query: 154  EEYEFLTPMEEAPKGMLARGSYNIKSRFTDDDKTDHLSWEWNLTI 198
            EE EF +  E+AP   + RGS    +  T DD TD L+ + N+ +
Sbjct: 1107 EEDEFASDDEDAPLFTIDRGSQEQSNNVTFDDATDSLNPDDNVEV 1241
>28038
          Length = 358

 Score = 26.6 bits (57), Expect = 8.1,   Method: Compositional matrix adjust.
 Identities = 20/54 (37%), Positives = 25/54 (46%)
 Frame = +2

Query: 84  GPLELDLTGDLESFKKQSFVLKEGVEYRIKISFRVNREIVSGMKYIQHTYRKGV 137
           GPLEL  TG++ S+     VL   V      +  VNR  VS   Y  H Y K +
Sbjct: 197 GPLEL*-TGNVTSWSLDRKVLPLSVSLLQLFAV*VNR*CVSSSDYKSHIYMKHI 355
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6754086|ref|NP_034490.1| glutathione S-transferase mu
5 [Mus musculus]
         (224 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

35754                                                                 182   1e-46
02955                                                                  54   4e-08
23210                                                                  29   1.3  
>35754
          Length = 581

 Score =  182 bits (462), Expect = 1e-46,   Method: Compositional matrix adjust.
 Identities = 88/182 (48%), Positives = 119/182 (65%), Gaps = 1/182 (0%)
 Frame = -2

Query: 38  CGEAPDYDRSQWLDVKFKLDLDFPNLPYLMDGKNKITQSNAILRYIARKHNMCGDTEEEK 97
            G+APD+ R  WL VK  L LDFPNLPY +DG  K+TQSNAILRYIARKHN+ G+T  E 
Sbjct: 556 TGDAPDFSRDAWLKVKSSLGLDFPNLPYYIDGDIKLTQSNAILRYIARKHNLMGETPLES 377

Query: 98  IRVDIMENQIMDFRMQLVRLCYNSNHENLKPQYLEQLPAQLKQFSLFLGKFTWFAGEKLT 157
            RV++M    MDFR  +VR+ YN  + +L  +Y  ++   L  F+ +L    WFAG+K+T
Sbjct: 376 ARVEMMLENAMDFRNGVVRMVYNPKYTDLLEEYKPKVKETLAGFNKYLADKKWFAGDKVT 197

Query: 158 FVDFLTYDVLDQNRI-FEPKCLDEFPNLKAFMCRFEALEKIAAFLQSDRFFKMPINNKMA 216
             DF  Y++LDQ+R+      L ++P L AFM  FEAL  I  ++ SD+F K P+NNK+A
Sbjct: 196 VADFHMYELLDQHRLMIGADVLKDYPKLTAFMAAFEALPAIKKYMASDKFMKRPVNNKVA 17

Query: 217 KW 218
            +
Sbjct: 16  AF 11
>02955
          Length = 1322

 Score = 54.3 bits (129), Expect = 4e-08,   Method: Compositional matrix adjust.
 Identities = 49/203 (24%), Positives = 83/203 (40%), Gaps = 9/203 (4%)
 Frame = +1

Query: 8   LGYWDIRGLAHAIRMLLEFTDTSYEEKRYICGEAPDYDRSQW-LDVKFKLDLDFPNLPYL 66
           L Y+++RG    +R+L       +E+KR         +R+ W  D   K    +  +PY+
Sbjct: 31  LYYFNVRGKGEFLRLLFRAAGVQFEDKRI--------ERADWGPDSDAKKATPYGQVPYV 186

Query: 67  MDGKNKITQSNAILRYIARKHNMCGDTEEEKIRVDIMENQIMDFRMQLVRLCYNSNHENL 126
           +    K  QS A+  Y ARK    G T+E+  + + + + I D  +   R  +       
Sbjct: 187 IYQGKKRGQSIAMGTYFARKFGFYGKTDEDAWKQEEIMHLIDDLIVGPNRAWFLEQDPQK 366

Query: 127 KPQYLEQL-----PAQLKQFSLFL---GKFTWFAGEKLTFVDFLTYDVLDQNRIFEPKCL 178
           K +   +L     P  L  F   L   G   +  G+ +T  D   +DVL+     +P+ L
Sbjct: 367 KAERTRELTEVQYPRYLSSFERLLAENGDQGYSVGDSVTLADLCLHDVLETVLGVDPRAL 546

Query: 179 DEFPNLKAFMCRFEALEKIAAFL 201
             FP  +      E L  +  +L
Sbjct: 547 XSFPLQRKLRANVENLPALKEYL 615
>23210
          Length = 944

 Score = 29.3 bits (64), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 16/45 (35%), Positives = 26/45 (57%), Gaps = 2/45 (4%)
 Frame = -1

Query: 59  DFPN--LPYLMDGKNKITQSNAILRYIARKHNMCGDTEEEKIRVD 101
           D PN   P+L     +  QS AI  ++AR++N+ G +  + IR+D
Sbjct: 686 DAPNGQAPFLEYKGKRYGQSIAIANFLARENNLYGKSNLDAIRID 552
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|11528490|ref|NP_071292.1| flightless I homolog [Mus
musculus]
         (1271 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

25837                                                                 184   2e-46
07901                                                                  82   2e-15
09469                                                                  79   8e-15
34576                                                                  78   2e-14
31845                                                                  62   1e-09
09309                                                                  56   7e-08
20421                                                                  56   1e-07
05532                                                                  51   2e-06
30747                                                                  44   4e-04
19955                                                                  42   0.002
13704                                                                  40   0.007
27907                                                                  37   0.047
15446                                                                  36   0.083
19531                                                                  36   0.12 
37214                                                                  35   0.23 
01109                                                                  31   2.7  
20480                                                                  31   4.0  
17623                                                                  30   4.6  
17298                                                                  30   5.1  
20775                                                                  29   9.4  
>25837
          Length = 421

 Score =  184 bits (467), Expect = 2e-46,   Method: Compositional matrix adjust.
 Identities = 92/152 (60%), Positives = 102/152 (67%)
 Frame = -1

Query: 871  DQMKADLTALFLPRQPPMPLAEAEQLMEEWNEDLDGMEGFVLEGRKFTRLPEEEFGHFYT 930
            D+M+ DL+ALF+PRQP MP  EAEQL  +WNEDLDGME FVLEG+KF RLP+EE G FYT
Sbjct: 403  DKMQTDLSALFMPRQPTMPADEAEQLSADWNEDLDGMESFVLEGKKFVRLPDEELGMFYT 224

Query: 931  QDCYVFLCRYWVPVXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXDFQCIVYFWQ 990
            +DCYVFLCRYWVPV                                     ++CIVYFWQ
Sbjct: 223  EDCYVFLCRYWVPVELPEGEEEDIDEEDLPEDE------------------YKCIVYFWQ 98

Query: 991  GREASNMGWLTFTFSLQKKFESLFPGKLEVVR 1022
            GR ASNMGWLTFTFSLQKKFESLF  KLEVVR
Sbjct: 97   GRHASNMGWLTFTFSLQKKFESLFGDKLEVVR 2
>07901
          Length = 1199

 Score = 81.6 bits (200), Expect = 2e-15,   Method: Compositional matrix adjust.
 Identities = 74/297 (24%), Positives = 123/297 (41%), Gaps = 7/297 (2%)
 Frame = +2

Query: 519 HGKFYEADCYIVLKTFLDD-SGSLNWEIYYWIGGEATLDKKACSAIHAVNLRNYLGAECR 577
           +G+FY  D YI+L T+ D+ +  LN+++++WIG  ++ D+   +A   V L   L  +  
Sbjct: 11  YGEFYNGDSYIILNTYKDEETEDLNYDVHFWIGKNSSQDEYGTAAYKTVELDTLLDDKPV 190

Query: 578 TVREEMGDESEEFLQVFDNDISYIEGGTASGFYTVE-DTHYVTRMYRVYGKK--NIKLEP 634
             RE  G ES  F   F   I  +EGG  SGF ++     Y+ R+ R    K  +I +  
Sbjct: 191 QHREVQGHESSLFKSYFKAGIQTMEGGANSGFRSIPVKEEYIPRLMRFAKDKSGHIVVRE 370

Query: 635 VPLKGSSLDPRFVFLLDQGLDIYVWRGAQATLSNTTKARLFAEKINKNERKGKAEITLLV 694
           +P     +    VF++D G  +Y + G+  +    +KA  +  KI    ++G A+  +L 
Sbjct: 371 IPRARQLVTSGDVFIMDAGXMLYQFNGSACSPMEKSKAMEYIGKIKS--KRGDADSEVLD 544

Query: 695 QGQEPP--GFWDVLGGEPSEIKNHVPDDFWPPQPXXXXXXXXXXXXXXPQINYKLSVEHK 752
           +    P   F+ +L  E  E  N   D+                            V   
Sbjct: 545 EADTSPNHAFFKMLDEEVDEDGNASDDEDCDNDKKL------------------CRVNTD 670

Query: 753 KRPKVELMPGMRLLQSLLDTRCVYILDCWSDVFIWLGRKSPRLVRAAALKLGQE-LC 808
            R   ++  G   L     +  V+I D    VF+W+G  +    +   L L    LC
Sbjct: 671 TRDYEDVKEGDVTLDDFK-SDDVFIYDSGDTVFVWVGSNASSAEKKNGLPLAHTYLC 838
>09469
          Length = 657

 Score = 79.3 bits (194), Expect = 8e-15,   Method: Composition-based stats.
 Identities = 56/183 (30%), Positives = 88/183 (48%), Gaps = 6/183 (3%)
 Frame = +1

Query: 496 GQLPGLTIWQIENFVPVLVEEAFHGKFYEADCYIVLKTFLD-DSGSLNWEIYYWIGGEAT 554
           G+ PG+ IW+I +F         +G F++ D YI+L T+ + +S  L +++++WIG  +T
Sbjct: 100 GKKPGIQIWRINSFKVETWPTDDYGTFFKGDSYIILNTYKEAESDKLLYDVHFWIGEFST 279

Query: 555 LDKKACSAIHAVNLRNYLGAECRTVREEMGDESEEFLQVFDNDISYIEGGTASGFYTVED 614
            D+   +A   V L   L       RE   +ESE F   F  +I Y  GG  SGF  V +
Sbjct: 280 QDEYGTAAYKTVELDTLLDDIPVQHREVQDNESELFRSYF-KEIIYEAGGADSGFRHVTE 456

Query: 615 THYVTRMYRVYGK-----KNIKLEPVPLKGSSLDPRFVFLLDQGLDIYVWRGAQATLSNT 669
             Y  R+++V  K     KN+    V L    +     ++LD G   Y + G  A+   T
Sbjct: 457 DKYKPRLFKVSTKTKGKSKNLVATEVKLNRDQITSDDAYILDDGACFYQFNGKTASKQET 636

Query: 670 TKA 672
            K+
Sbjct: 637 FKS 645
>34576
          Length = 1496

 Score = 77.8 bits (190), Expect = 2e-14,   Method: Compositional matrix adjust.
 Identities = 56/165 (33%), Positives = 87/165 (52%), Gaps = 1/165 (0%)
 Frame = +2

Query: 23  GYFPENVKAMTSLRWLKLNRTGLCYLPEELAALQKLEHLSVSHNHLTTLHGELSSLPSLR 82
             F   + A+  L+    +  GL  LPEE++ L  L+ L +S+N          S+P L 
Sbjct: 500 SVFCAELCALQKLQMADFSNNGLLDLPEEVSVLGCLQELDLSNNQFFEFPKTACSIPHLH 679

Query: 83  AIV-ARANSLKNSGVPDDIFKLDDLSVLDLSHNQLTECPRELENAKNMLVLNLSHNGIDS 141
            +V ++   LK   +PD+I +   ++ L LSHN L   PR +   KN++VL   HN I  
Sbjct: 680 KLVFSQQEGLKVPSLPDEI-EFSSVAELVLSHNTLRTLPRTISAMKNLVVLKADHNEICV 856

Query: 142 IPNQLFINLTDLLYLDLSENRLESLPPQMRRLVHLQTLVLNGNPL 186
           +P+ L  ++T L  L L++N L +LP +  +L  LQ L L+ NPL
Sbjct: 857 LPDAL-CDMTALQVLHLNDNLLPTLPLEFDQLKGLQDLCLHNNPL 988

 Score = 77.0 bits (188), Expect = 4e-14,   Method: Compositional matrix adjust.
 Identities = 88/356 (24%), Positives = 141/356 (39%)
 Frame = +2

Query: 25  FPENVKAMTSLRWLKLNRTGLCYLPEELAALQKLEHLSVSHNHLTTLHGELSSLPSLRAI 84
            PE++  +  L+ +      L  +PE +     LE LS+  NHL  L  E ++L  +  +
Sbjct: 23  LPEDIAELFELKEVYCGSNQLTLIPESICWCSNLEILSLHKNHLERLPVEFANLRKITRL 202

Query: 85  VARANSLKNSGVPDDIFKLDDLSVLDLSHNQLTECPRELENAKNMLVLNLSHNGIDSIPN 144
           +   N+   + VP  I  L +L  L L  N L E P+EL   K +  L+L  N     P 
Sbjct: 203 ILSDNNF--TSVPVAIGSLTELEALLLDGNSLHEIPQELGTLKKLTHLSLGRNAFKEFPR 376

Query: 145 QLFINLTDLLYLDLSENRLESLPPQMRRLVHLQTLVLNGNPLLHAQLRQLPAMMALQTLH 204
               ++T L  LDLS+N++  +P  + +L+ L+ L +  N  +     +L A+  LQ   
Sbjct: 377 PA-CSITSLEILDLSDNKITEIPSDIAQLLSLRELYMKKNA-VSVFCAELCALQKLQMAD 550

Query: 205 LRNTQRTQSNLPTSLEGLSNLSDVDLSCNDLTRVPECLYTLPXXXXXXXXXXQIAELSLC 264
             N      +LP  +  L  L ++DLS N     P+   ++P                  
Sbjct: 551 FSNNGLL--DLPEEVSVLGCLQELDLSNNQFFEFPKTACSIP------------------ 670

Query: 265 IDQWVHLETLNLSRNQLTSLPSAICXXXXXXXXXXXXXXXDFDGLPSGIGKLTSLEEFMA 324
                HL  L  S+ +   +PS                      LP  I  + +L    A
Sbjct: 671 -----HLHKLVFSQQEGLKVPSLPDEIEFSSVAELVLSHNTLRTLPRTISAMKNLVVLKA 835

Query: 325 ANNNLELIPESLCRCPXXXXXXXXXXXXXTLPEAIHFLTEIQVLDVRENPSLVMPP 380
            +N + ++P++LC                TLP     L  +Q L +  NP L  PP
Sbjct: 836 DHNEICVLPDALCDMTALQVLHLNDNLLPTLPLEFDQLKGLQDLCLHNNP-LRSPP 1000

 Score = 69.7 bits (169), Expect = 6e-12,   Method: Compositional matrix adjust.
 Identities = 74/276 (26%), Positives = 122/276 (44%), Gaps = 1/276 (0%)
 Frame = +2

Query: 15  LSGNDFKGGYFPENVKAMTSLRWLKLNRTGLCYLPEELAALQKLEHLSVSHNHLTTLHGE 74
           LS N+F     P  + ++T L  L L+   L  +P+EL  L+KL HLS+  N        
Sbjct: 206 LSDNNFTS--VPVAIGSLTELEALLLDGNSLHEIPQELGTLKKLTHLSLGRNAFKEFPRP 379

Query: 75  LSSLPSLRAIVARANSLKNSGVPDDIFKLDDLSVLDLSHNQLTECPRELENAKNMLVLNL 134
             S+ SL  +    N  K + +P DI +L  L  L +  N ++    EL   + + + + 
Sbjct: 380 ACSITSLEILDLSDN--KITEIPSDIAQLLSLRELYMKKNAVSVFCAELCALQKLQMADF 553

Query: 135 SHNGIDSIPNQLFINLTDLLYLDLSENRLESLPPQMRRLVHLQTLVLNGNPLLHAQLRQL 194
           S+NG+  +P ++ + L  L  LDLS N+    P     + HL  LV +    L  ++  L
Sbjct: 554 SNNGLLDLPEEVSV-LGCLQELDLSNNQFFEFPKTACSIPHLHKLVFSQQEGL--KVPSL 724

Query: 195 PAMMALQTL-HLRNTQRTQSNLPTSLEGLSNLSDVDLSCNDLTRVPECLYTLPXXXXXXX 253
           P  +   ++  L  +  T   LP ++  + NL  +    N++  +P+ L  +        
Sbjct: 725 PDEIEFSSVAELVLSHNTLRTLPRTISAMKNLVVLKADHNEICVLPDALCDMTALQVLHL 904

Query: 254 XXXQIAELSLCIDQWVHLETLNLSRNQLTSLPSAIC 289
               +  L L  DQ   L+ L L  N L S P  +C
Sbjct: 905 NDNLLPTLPLEFDQLKGLQDLCLHNNPLRSPPMDVC 1012
>31845
          Length = 409

 Score = 62.4 bits (150), Expect = 1e-09,   Method: Composition-based stats.
 Identities = 38/114 (33%), Positives = 60/114 (52%), Gaps = 1/114 (0%)
 Frame = -1

Query: 496 GQLPGLTIWQIENFVPVLVEEAFHGKFYEADCYIVLKTFLDDSG-SLNWEIYYWIGGEAT 554
           G+  GL IW+I  F      +  +GKFY  D YI+L T+ ++ G  L +++++WIG E+T
Sbjct: 370 GKRVGLQIWRIVKFQVKAWPKEDYGKFYSGDSYIILNTYKEEGGDELLFDVHFWIGKEST 191

Query: 555 LDKKACSAIHAVNLRNYLGAECRTVREEMGDESEEFLQVFDNDISYIEGGTASG 608
            D+   +A   V L  +L       RE  G ES+ F   F   ++Y++G    G
Sbjct: 190 QDEYGTAAYKTVELDTFLDDLPIQHREVQGHESDMFKSYF-KALTYMKGVQTPG 32
>09309
          Length = 1508

 Score = 56.2 bits (134), Expect = 7e-08,   Method: Compositional matrix adjust.
 Identities = 55/197 (27%), Positives = 87/197 (44%), Gaps = 1/197 (0%)
 Frame = +3

Query: 10  VRGVDLSGNDFKGGYFPENVKAMT-SLRWLKLNRTGLCYLPEELAALQKLEHLSVSHNHL 68
           V  V++S N F     P N+  +  SL  L +    L  L  ++    KL  L + +N L
Sbjct: 438 VTSVNISKNQFT--QLPSNLFLLVNSLTELNMGFNKLTGLSPDIGLFLKLTCLDLRNNGL 611

Query: 69  TTLHGELSSLPSLRAIVARANSLKNSGVPDDIFKLDDLSVLDLSHNQLTECPRELENAKN 128
           ++L  EL S+ +LR ++                         LS N+ TE P+ L   K 
Sbjct: 612 SSLPAELCSMQALREVI-------------------------LSCNRFTEIPQALYELKK 716

Query: 129 MLVLNLSHNGIDSIPNQLFINLTDLLYLDLSENRLESLPPQMRRLVHLQTLVLNGNPLLH 188
           + +L L+ N + +I       L  L  LDL  N +  +PP++     L++L L GNP  +
Sbjct: 717 LEILFLNDNQVSTIEPSGLQRLGVLATLDLQNNNISQVPPELGNCTSLRSLQLGGNPCRN 896

Query: 189 AQLRQLPAMMALQTLHL 205
            +    PA++A  TL L
Sbjct: 897 PR----PAILAKGTLAL 935

 Score = 35.4 bits (80), Expect = 0.14,   Method: Compositional matrix adjust.
 Identities = 74/316 (23%), Positives = 128/316 (40%), Gaps = 7/316 (2%)
 Frame = +3

Query: 75  LSSLPSLRAIVARANSLKNSGVPDDIFKLDDLSVLDLSHNQLTECPRELENAKNMLVLNL 134
           L  L +L  +  R N L  + +PD+I  L++L  LDLS+N ++  P  L    ++  + L
Sbjct: 6   LQHLSTLNFLDVRDNKL--AKLPDEITLLENLERLDLSNNDISMLPYSLGTINSLKSVIL 179

Query: 135 SHNGIDSIPNQLFINLTDLL--YLDLSENRLESLPPQMRRLVHLQTLVLNGNPLLHAQLR 192
             N + SI   + +  T  L  YL    +R+E  P      V  +  VL   P      +
Sbjct: 180 DGNPMKSIRRDIIMRGTMELKKYL---RSRIEE-PESRPAPVTSKESVL---PTGSGDTQ 338

Query: 193 QLPAMMALQTLHLRNTQRTQSNLPTSL---EGLSNLSDVDLSCNDLTRVPECLYTLPXXX 249
           Q   M   +T+    + +  + +P  +      + ++ V++S N  T++P  L+ L    
Sbjct: 339 QAHEMQQFKTMDF--SGKNANAVPADMWEKAQEAAVTSVNISKNQFTQLPSNLFLLVNSL 512

Query: 250 XXXXXX-XQIAELSLCIDQWVHLETLNLSRNQLTSLPSAICXXXXXXXXXXXXXXXDFDG 308
                   ++  LS  I  ++ L  L+L  N L+SLP+ +C                F  
Sbjct: 513 TELNMGFNKLTGLSPDIGLFLKLTCLDLRNNGLSSLPAELCSMQALREVILSCNR--FTE 686

Query: 309 LPSGIGKLTSLEEFMAANNNLELI-PESLCRCPXXXXXXXXXXXXXTLPEAIHFLTEIQV 367
           +P  + +L  LE     +N +  I P  L R                +P  +   T ++ 
Sbjct: 687 IPQALYELKKLEILFLNDNQVSTIEPSGLQRLGVLATLDLQNNNISQVPPELGNCTSLRS 866

Query: 368 LDVRENPSLVMPPKPA 383
           L +  NP     P+PA
Sbjct: 867 LQLGGNP--CRNPRPA 908
>20421
          Length = 455

 Score = 55.8 bits (133), Expect = 1e-07,   Method: Composition-based stats.
 Identities = 26/78 (33%), Positives = 48/78 (61%)
 Frame = +3

Query: 503 IWQIENFVPVLVEEAFHGKFYEADCYIVLKTFLDDSGSLNWEIYYWIGGEATLDKKACSA 562
           +W+++NF    ++++ +G+FY  DCY++  T+    G  +  IY+W+G ++T D+K  +A
Sbjct: 81  VWRVDNFDLKPLDKSRYGEFYGGDCYVIQYTY-KVHGRDHVIIYFWLGSKSTADEKGTAA 257

Query: 563 IHAVNLRNYLGAECRTVR 580
           + AV L + LG     VR
Sbjct: 258 LKAVELDDKLGGSPVQVR 311
>05532
          Length = 1607

 Score = 51.2 bits (121), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 38/125 (30%), Positives = 64/125 (51%), Gaps = 3/125 (2%)
 Frame = +3

Query: 95  GVPDDIFKLDDLSVLDLSHNQLTECPRELENAKNMLVLNLSHNGIDSIPNQLFINLTDLL 154
            +  ++F+   L+ L L+ N+L      +    +++ L+LS N + S+P+++  +LT+L 
Sbjct: 150 NISPELFRFQHLTCLYLNDNRLDHISPHVSQLHHLVCLDLSSNQLSSLPSEIG-DLTELR 326

Query: 155 YLDLSENRLESLPPQMRRLVHLQTLVLNGNPLLHAQLRQLPAMMA---LQTLHLRNTQRT 211
            L L  N+L SLP ++ RL  LQ L + GNPL    +     M     L +  L N   T
Sbjct: 327 ELLLYNNQLTSLPFELGRLFQLQNLDIKGNPLSQDYMHFYQGMNGTNDLLSFLLDNMPYT 506

Query: 212 QSNLP 216
            + LP
Sbjct: 507 STQLP 521

 Score = 33.5 bits (75), Expect = 0.56,   Method: Compositional matrix adjust.
 Identities = 26/82 (31%), Positives = 34/82 (41%)
 Frame = +3

Query: 257 QIAELSLCIDQWVHLETLNLSRNQLTSLPSAICXXXXXXXXXXXXXXXDFDGLPSGIGKL 316
           ++  +S  + Q  HL  L+LS NQL+SLPS                          IG L
Sbjct: 210 RLDHISPHVSQLHHLVCLDLSSNQLSSLPSE-------------------------IGDL 314

Query: 317 TSLEEFMAANNNLELIPESLCR 338
           T L E +  NN L  +P  L R
Sbjct: 315 TELRELLLYNNQLTSLPFELGR 380
>30747
          Length = 1168

 Score = 43.9 bits (102), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 60/210 (28%), Positives = 95/210 (45%), Gaps = 19/210 (9%)
 Frame = +3

Query: 94  SGVPDDIFKLDDLSVLDLSHNQLTECPRELENAKNMLVLNLSHNGIDSIPNQLFINLTDL 153
           + VPD + K   L VLD+S N +T+  + LE  +++  L L  N +  +  Q   +L +L
Sbjct: 234 TAVPD-LEKFRKLRVLDVSGNYITKI-QHLEFTQDLRDLKLYDNKVSQV--QGLESLKEL 401

Query: 154 LYLDLSENRLESLPPQMRRLVHLQTLVLNGNPLLHAQLRQLPAMMALQTLHLRNTQRTQ- 212
             L L  N++ESL   +  L  L+ L L+ N L      +L + + + TL L N   T  
Sbjct: 402 CSLQLQYNQIESLGKGLNALKKLKCLRLDSNRLTKLDTNELLSCVNISTLDLSNNHITNL 581

Query: 213 ---SNLP---------------TSLEGLSNLSDVDLSCNDLTRVPECLYTLPXXXXXXXX 254
              S LP               T L     LS++DLS N L  +   +  LP        
Sbjct: 582 SALSYLPNLEELFVSGNSIQKLTDLHRCKKLSELDLSRNRLVDISG-ISGLPALQTLDMS 758

Query: 255 XXQIAELSLCIDQWVHLETLNLSRNQLTSL 284
             ++  ++  + +   LETLNL+ NQ++ L
Sbjct: 759 DNRLKSVT-SLGKLKSLETLNLNGNQISEL 845
>19955
          Length = 634

 Score = 42.0 bits (97), Expect = 0.002,   Method: Composition-based stats.
 Identities = 33/86 (38%), Positives = 47/86 (54%)
 Frame = -2

Query: 52  LAALQKLEHLSVSHNHLTTLHGELSSLPSLRAIVARANSLKNSGVPDDIFKLDDLSVLDL 111
           L +L++L  L +  N +  + G LSSL SLR ++   N +K     D + KLD   VLDL
Sbjct: 243 LNSLRRLIFLDLYDNQIEQIAG-LSSLKSLRVLMLGKNRIKRIENLDTLIKLD---VLDL 76

Query: 112 SHNQLTECPRELENAKNMLVLNLSHN 137
             NQ+T     L +   +LVLNL+ N
Sbjct: 75  HGNQITRI-ENLNHLGELLVLNLAGN 1
>13704
          Length = 488

 Score = 39.7 bits (91), Expect = 0.007,   Method: Composition-based stats.
 Identities = 16/25 (64%), Positives = 21/25 (84%)
 Frame = -1

Query: 139 IDSIPNQLFINLTDLLYLDLSENRL 163
           I+ IPNQLFINLTD++++D S N L
Sbjct: 293 IEMIPNQLFINLTDVVFVDFSNNNL 219
>27907
          Length = 426

 Score = 37.0 bits (84), Expect = 0.047,   Method: Compositional matrix adjust.
 Identities = 21/79 (26%), Positives = 34/79 (43%), Gaps = 2/79 (2%)
 Frame = +2

Query: 763 MRLLQSLLDTRCVYILDCWSDVFIWLGRKSPRLVRAAALKLGQELCGM--LHRPRHTVVS 820
           +  +Q  L    V +LDCW  +++W+G+ S +  R  A  L  +        R   T + 
Sbjct: 44  LDFVQDDLIPEDVMLLDCWECLYLWVGQGSNKAERQGAQNLALDYLKTDPAGRDPDTPIM 223

Query: 821 RSLEGTEAQVFKAKFKNWD 839
           +  +G E   F   F  WD
Sbjct: 224 KISQGYEPPSFTGFFGTWD 280
>15446
          Length = 401

 Score = 36.2 bits (82), Expect = 0.083,   Method: Composition-based stats.
 Identities = 32/108 (29%), Positives = 51/108 (47%), Gaps = 6/108 (5%)
 Frame = -3

Query: 44  GLCYLPEELAALQKLEHLSVSHNHLTTLH-GELSSLPSLRAIVARANSLK--NSGVPDDI 100
           GL  +P +L        L +  N +T+L  G+   L  L  +    N +   N  +  D+
Sbjct: 303 GLVEVPNDLQLRSWGTRLELQSNGITSLEAGDFKGLHMLEELYLSHNDITFINGSIFQDL 124

Query: 101 FKLDDLSVLDLSHNQLTEC---PRELENAKNMLVLNLSHNGIDSIPNQ 145
            KL  L +   +HN+LTE    PR L    N+  L+L+HN I +I ++
Sbjct: 123 IKLHTLKI---THNKLTEMPVFPRHL----NITELSLAHNMIHTISHE 1
>19531
          Length = 415

 Score = 35.8 bits (81), Expect = 0.12,   Method: Compositional matrix adjust.
 Identities = 37/148 (25%), Positives = 57/148 (38%)
 Frame = -2

Query: 223 SNLSDVDLSCNDLTRVPECLYTLPXXXXXXXXXXQIAELSLCIDQWVHLETLNLSRNQLT 282
           ++L+ + L+ N LT + E L  LP           +  L   + +  +L+ LN+S NQL 
Sbjct: 372 TDLTKLILASNALTSLGEGLAQLPALTVLDVHDNHLQSLPNALGELENLQKLNISHNQLV 193

Query: 283 SLPSAICXXXXXXXXXXXXXXXDFDGLPSGIGKLTSLEEFMAANNNLELIPESLCRCPXX 342
            LPS                          IG+L++L    A +N L LI   L  C   
Sbjct: 192 ELPSC-------------------------IGRLSNLVSVHAEHNKLTLICPDLVDCRKL 88

Query: 343 XXXXXXXXXXXTLPEAIHFLTEIQVLDV 370
                       LP+ I  L+ +  L+V
Sbjct: 87  EELDVSNNDLAELPKYIGLLSRMFRLNV 4

 Score = 35.0 bits (79), Expect = 0.20,   Method: Compositional matrix adjust.
 Identities = 32/120 (26%), Positives = 61/120 (50%)
 Frame = -2

Query: 81  LRAIVARANSLKNSGVPDDIFKLDDLSVLDLSHNQLTECPRELENAKNMLVLNLSHNGID 140
           L  ++  +N+L + G  + + +L  L+VLD+  N L   P  L   +N+  LN+SHN + 
Sbjct: 366 LTKLILASNALTSLG--EGLAQLPALTVLDVHDNHLQSLPNALGELENLQKLNISHNQLV 193

Query: 141 SIPNQLFINLTDLLYLDLSENRLESLPPQMRRLVHLQTLVLNGNPLLHAQLRQLPAMMAL 200
            +P+ +   L++L+ +    N+L  + P +     L+ L ++ N      L +LP  + L
Sbjct: 192 ELPSCIG-RLSNLVSVHAEHNKLTLICPDLVDCRKLEELDVSNN-----DLAELPKYIGL 31
>37214
          Length = 316

 Score = 34.7 bits (78), Expect = 0.23,   Method: Composition-based stats.
 Identities = 22/60 (36%), Positives = 31/60 (51%), Gaps = 6/60 (10%)
 Frame = -2

Query: 108 VLDLSHNQLTEC------PRELENAKNMLVLNLSHNGIDSIPNQLFINLTDLLYLDLSEN 161
           ++ L+H    +C      P  L    N+  L LS N I SIP  +F +L +L +LDLS N
Sbjct: 186 LVHLTHLSARKCFLDSLFPGMLHAFSNLSTLQLSDNKISSIPEGVFDSLHNLSHLDLSGN 7
>01109
          Length = 2130

 Score = 31.2 bits (69), Expect = 2.7,   Method: Compositional matrix adjust.
 Identities = 33/112 (29%), Positives = 52/112 (46%), Gaps = 15/112 (13%)
 Frame = +3

Query: 27  ENVKAMTSLRWLKLN-----RTGLCYLPEELAALQKLEHLSVSHNHLTTLHGELSSLPS- 80
           E +   T LR L LN      TG   + + L  LQ+LE ++     L T  G L+   + 
Sbjct: 519 EAIAVNTKLRVLNLNDNTFTETGSHEMAKVLPKLQELEVINFGDCLLRT-GGALAIADAV 695

Query: 81  ------LRAIVARANSLKNSG---VPDDIFKLDDLSVLDLSHNQLTECPREL 123
                 L+ ++   N +K +G   + + +    DL++LDL+ NQL E   EL
Sbjct: 696 KDGQHKLKELILSGNEIKQNGAVAITESLANKQDLTLLDLNANQLGEGGIEL 851
>20480
          Length = 638

 Score = 30.8 bits (68), Expect = 4.0,   Method: Compositional matrix adjust.
 Identities = 16/43 (37%), Positives = 28/43 (65%)
 Frame = -2

Query: 142 IPNQLFINLTDLLYLDLSENRLESLPPQMRRLVHLQTLVLNGN 184
           +P+ +F +L  L+ L LS N++  +P  +  L +L+ LVL+GN
Sbjct: 595 MPDPVF-DLEQLVCLSLSNNKITEIPDAISHLDNLEVLVLSGN 470
>17623
          Length = 687

 Score = 30.4 bits (67), Expect = 4.6,   Method: Compositional matrix adjust.
 Identities = 19/57 (33%), Positives = 34/57 (59%)
 Frame = +2

Query: 147 FINLTDLLYLDLSENRLESLPPQMRRLVHLQTLVLNGNPLLHAQLRQLPAMMALQTL 203
             +L +L  L+L+EN++E L   +   +HL+ L L+GNP+  + LR +  ++ L  L
Sbjct: 314 LTHLVNLKELNLAENKIEKLGHSLDSNIHLEDLNLSGNPI--SSLRDVTNLVRLPQL 478
>17298
          Length = 476

 Score = 30.4 bits (67), Expect = 5.1,   Method: Compositional matrix adjust.
 Identities = 22/63 (34%), Positives = 37/63 (58%)
 Frame = +3

Query: 112 SHNQLTECPRELENAKNMLVLNLSHNGIDSIPNQLFINLTDLLYLDLSENRLESLPPQMR 171
           ++N +T+ P +L +  ++  LNL+ N I+ +PN+L    T L  L LS N+++      R
Sbjct: 261 NNNAITDVPADLSSLPHLNCLNLADNQIEELPNEL-CECTRLKELKLSGNKIKD-----R 422

Query: 172 RLV 174
           RLV
Sbjct: 423 RLV 431
>20775
          Length = 1020

 Score = 29.3 bits (64), Expect = 9.4,   Method: Composition-based stats.
 Identities = 34/162 (20%), Positives = 72/162 (44%), Gaps = 2/162 (1%)
 Frame = -3

Query: 125 NAKNMLVLNLSHNGIDSIPNQLFINLTDLLYLDLSENRLESLPPQMRRLVHLQTLVLNGN 184
           N+  ++ L+LS N + ++P+  F+N   +  L L  N   +LP  + ++ H + L ++ +
Sbjct: 595 NSVTLINLDLSGNNLSTLPDN-FLNGEIIDSLILKNNNFTALPVALTKVEHXRRLDVSFS 419

Query: 185 PLLHAQLRQLPAMMALQTLHL-RNTQRTQSNLPTSLEG-LSNLSDVDLSCNDLTRVPECL 242
            L+      L  +  L+ + +  N     S +  S  G +    +++L+ N + R+ +  
Sbjct: 418 ALVSFSFDILENVSGLEMVDMSSNKLLYASTVGESSAGVMLGXKELNLASNAIDRIEDGF 239

Query: 243 YTLPXXXXXXXXXXQIAELSLCIDQWVHLETLNLSRNQLTSL 284
           ++                    +D+   L TLNLS N L+ +
Sbjct: 238 FSR-------------------MDK---LTTLNLSDNHLSQV 179
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|13385872|ref|NP_080650.1| interleukin enhancer
binding factor 2 [Mus musculus]
         (390 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

27201                                                                 182   2e-46
36554                                                                 128   5e-30
01447                                                                  30   2.4  
>27201
          Length = 515

 Score =  182 bits (462), Expect = 2e-46,   Method: Compositional matrix adjust.
 Identities = 89/156 (57%), Positives = 115/156 (73%), Gaps = 6/156 (3%)
 Frame = +2

Query: 98  QIEEVRQVGSYKKGTMTTGHNVADLVVILKILPTLEAVAALGNKVVESLRAQDPSEVLT- 156
           Q+EEVRQVGS+KKGT+ TG+NVAD+VVILK LPT E+  AL  KV   L+    +EVLT 
Sbjct: 17  QLEEVRQVGSFKKGTILTGNNVADVVVILKTLPTKESCEALAKKVEADLKTSMKTEVLTK 196

Query: 157 -----MLTNETGFEISSSDATVKILITTVPPNLRKLDPELHLDIKVLQSALAAIRHARWF 211
                +  ++ GF++S+S A V+ILI T+P NLRKL+ ++H+D K +QS LAAIRH RWF
Sbjct: 197 GEQHSIQIHDRGFDVSNSQAKVRILIATLPQNLRKLEADIHMDQKYMQSHLAAIRHTRWF 376

Query: 212 EENASQSTVKVLIRLLKDLRIRFPGFEPLTPWILDL 247
           EENA  S++KVLIR+LKDL  RF  F PL+ W+LD 
Sbjct: 377 EENAHHSSIKVLIRILKDLTKRFDAFSPLSAWMLDF 484
>36554
          Length = 262

 Score =  128 bits (321), Expect = 5e-30,   Method: Compositional matrix adjust.
 Identities = 58/81 (71%), Positives = 72/81 (88%)
 Frame = +3

Query: 272 LQILAAGLFLPGSVGITDPCESGNFRVHTVMTLEQQDMVCYTAQTLVRILSHGGFRKILG 331
           LQ+L++GLFLPGSVGI DPCE G  RVH VMTLEQQD VC+TAQTL+R+LSHGGF++ILG
Sbjct: 3   LQLLSSGLFLPGSVGIADPCEQGTVRVHVVMTLEQQDQVCFTAQTLLRVLSHGGFKQILG 182

Query: 332 QEGDASYLASEISTWDGVIVT 352
            EG+AS +A+E+S W+GV+VT
Sbjct: 183 LEGNAS-IATEMSVWEGVVVT 242
>01447
          Length = 1862

 Score = 29.6 bits (65), Expect = 2.4,   Method: Compositional matrix adjust.
 Identities = 31/122 (25%), Positives = 53/122 (43%), Gaps = 9/122 (7%)
 Frame = -3

Query: 107 SYKKGTMTTGHNVADLVVILKILPTLEAVAALGNKVVESLRAQDPSEVLTMLTNETGFEI 166
           S+ K +++T   V  L++I+         + +G KV        PS+V+ ++ ++  F  
Sbjct: 597 SFGKNSLSTI*CVFKLLIII-----YNPFSRMGAKVANLEWR*SPSKVIMVILDD*DF-- 439

Query: 167 SSSDATVKILITTVPPN----LRKLDPELHLDIKVLQSAL-----AAIRHARWFEENASQ 217
                   I  TT PP     + K DPE+HL++  +   L       I + R+ E  AS 
Sbjct: 438 -------LIF*TT*PPKSIMLIEKFDPEMHLNVNFI*KTLNN*DFTQIYNLRFLEMTASS 280

Query: 218 ST 219
            T
Sbjct: 279 PT 274
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|13385392|ref|NP_080174.1| N-ethylmaleimide sensitive
fusion protein attachment protein alpha [Mus musculus]
         (295 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

37486                                                                 181   3e-46
15991                                                                  29   2.8  
>37486
          Length = 471

 Score =  181 bits (460), Expect = 3e-46,   Method: Compositional matrix adjust.
 Identities = 82/127 (64%), Positives = 109/127 (85%)
 Frame = -2

Query: 166 LKVAGYAAQLEQYQKAIDIYEQVGTSAMDSPLLKYSAKDYFFKAALCHFCIDMLNAKLAV 225
           LKVA Y+AQLE Y+KAIDIYEQ+G  AMD+ LLKYSAKD+FF+A +CH C+D++NA+L+V
Sbjct: 470 LKVAEYSAQLENYEKAIDIYEQLGMFAMDNSLLKYSAKDHFFRACVCHMCVDLVNAQLSV 291

Query: 226 QKYEELFPAFSDSRECKLMKKLLEAHEEQNVDSYTEAVKEYDSISRLDQWLTTMLLRIKK 285
           QKYEE+FPAF+DSRECKL+K LL+A EE+N D +TEA+++YDSISRLD+ +T M L++KK
Sbjct: 290 QKYEEMFPAFTDSRECKLVKSLLKACEEENADDFTEALRQYDSISRLDKNVTAMFLKVKK 111

Query: 286 TIQGDEE 292
            +  + E
Sbjct: 110 QLNAEPE 90
>15991
          Length = 1629

 Score = 28.9 bits (63), Expect = 2.8,   Method: Compositional matrix adjust.
 Identities = 10/37 (27%), Positives = 22/37 (59%)
 Frame = +2

Query: 107 AIEIYTDMGRFTIAAKHHISIAEIYETELVDVEKAIA 143
           +IE+ + +GR  +A    ++ A++ + ++ DVE  I 
Sbjct: 656 SIEVLSSLGRVVLAVTSDVATADVLDGDVFDVESHIV 766
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|157823695|ref|NP_057914.2| kinesin family member 21A
isoform 3 [Mus musculus]
         (1573 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

33215                                                                 184   3e-46
11818                                                                 121   7e-43
28434                                                                 172   9e-43
12048                                                                 152   8e-37
38050                                                                  65   4e-31
17748                                                                  79   5e-30
13148                                                                  92   3e-27
02896                                                                 112   1e-24
34477                                                                 105   1e-22
15043                                                                  97   6e-20
14618                                                                  94   4e-19
30256                                                                  74   5e-13
34899                                                                  69   1e-11
00561                                                                  64   6e-10
18792                                                                  57   7e-08
17602                                                                  52   2e-06
36593                                                                  52   2e-06
19949                                                                  51   3e-06
03395                                                                  50   8e-06
12806                                                                  49   2e-05
26107                                                                  48   3e-05
17598                                                                  48   3e-05
10162                                                                  45   2e-04
18981                                                                  45   2e-04
27465                                                                  45   3e-04
38061                                                                  42   0.001
11493                                                                  42   0.001
13335                                                                  42   0.002
21105                                                                  40   0.005
37180                                                                  40   0.009
27806                                                                  39   0.021
01462                                                                  38   0.032
02147                                                                  38   0.037
22114                                                                  38   0.038
02960                                                                  37   0.058
02090                                                                  37   0.075
03387                                                                  37   0.087
26939                                                                  35   0.18 
01327                                                                  35   0.26 
14555                                                                  35   0.31 
17266                                                                  34   0.40 
05393                                                                  34   0.45 
31384                                                                  34   0.56 
12574                                                                  33   1.00 
03156                                                                  33   1.2  
35695                                                                  32   1.4  
18320                                                                  32   2.1  
01598                                                                  32   2.4  
05303                                                                  32   2.6  
06576                                                                  31   3.2  
23766                                                                  30   5.4  
16199                                                                  30   6.1  
01258                                                                  30   9.0  
>33215
          Length = 696

 Score =  184 bits (466), Expect = 3e-46,   Method: Compositional matrix adjust.
 Identities = 106/255 (41%), Positives = 146/255 (57%)
 Frame = +1

Query: 148 FLELYNEEVLDLFDTTRDIDAKNKKSNIRIHEDSTGGIYTVGVTTRTVNTEPEMMQCLKL 207
           +LE+Y EE+ DL        +K++   + +      G+Y   +++    +  E+   + +
Sbjct: 1   YLEIYQEEIRDLL-------SKDQSKRLELKXRPDTGVYVKDLSSFVTKSVREIEHVMNV 159

Query: 208 GALSRTTASTQMNVQSSRSHAIFTIHVCQTRVCPQTDAENATDNKLISESSPMNEFETLT 267
           G  +R+  +T MN  SSRSHAIF I V     C +  A+               E     
Sbjct: 160 GNQNRSVGATNMNEHSSRSHAIFIITV----ECSEIGADG--------------ENHIRV 285

Query: 268 AKFHFVDLAGSERLKRTGATGERAKEGISINCGLLALGNVISALGDKSKRATHVPYRDSK 327
            K + VDLAGSER  +TGATG+R KE   IN  L AL NVISAL D   + TH+PYRDSK
Sbjct: 286 GKLNMVDLAGSERQAKTGATGDRLKEATKINLSLSALSNVISALVDA--KTTHIPYRDSK 459

Query: 328 LTRLLQDSLGGNSQTIMIACVSPSDRDFMETLNTLKYANRARNIKNKVMVNQDRASQQIN 387
           LTRLLQDSLGGNS+T M+A + P+  +F ETL TL+YANRA++IKNK  +N+D     + 
Sbjct: 460 LTRLLQDSLGGNSKTTMVANIGPASYNFDETLTTLRYANRAKSIKNKPKINEDPKDALLR 639

Query: 388 ALRSEITRLQMELME 402
             + EI RL+ +L E
Sbjct: 640 EFQDEINRLKNQLSE 684
>11818
          Length = 657

 Score =  121 bits (304), Expect(2) = 7e-43,   Method: Compositional matrix adjust.
 Identities = 79/216 (36%), Positives = 112/216 (51%), Gaps = 2/216 (0%)
 Frame = -1

Query: 92  AGKTYTMGTGFDVNIMEEEQ--GIISRAVRHLFKSIDEKKTSAIKNGLPPPEFKVNAQFL 149
           +GKTYTMG  +D  +  ++   GII R +  LF  I E+             FKV   +L
Sbjct: 657 SGKTYTMGGCYDAALSHDDDLVGIIPRILGDLFNGIAERSDYT---------FKVTVSYL 505

Query: 150 ELYNEEVLDLFDTTRDIDAKNKKSNIRIHEDSTGGIYTVGVTTRTVNTEPEMMQCLKLGA 209
           E+YNE++LDL      +   +++  + I E+  G I   G+    V +  + + CL  GA
Sbjct: 504 EIYNEDLLDL------LCLPSQRQPLSIREEMNGEIKIKGLKEVEVGSLEDTLMCLSQGA 343

Query: 210 LSRTTASTQMNVQSSRSHAIFTIHVCQTRVCPQTDAENATDNKLISESSPMNEFETLTAK 269
            SRTT +T MN  SSRSHAIFT+H+       ++  E+  D+ +              AK
Sbjct: 342 RSRTTGATAMNDTSSRSHAIFTVHI------EKSKKEDMNDHCI--------------AK 223

Query: 270 FHFVDLAGSERLKRTGATGERAKEGISINCGLLALG 305
           FH VDLAGSER K+T A G+R KEG++I    L  G
Sbjct: 222 FHLVDLAGSERAKKTRAEGDRFKEGVNITVACLPWG 115

 Score = 72.4 bits (176), Expect(2) = 7e-43,   Method: Composition-based stats.
 Identities = 34/44 (77%), Positives = 39/44 (88%)
 Frame = -3

Query: 300 GLLALGNVISALGDKSKRATHVPYRDSKLTRLLQDSLGGNSQTI 343
           GLLALGNVISALG+  ++  H+PYRDSKLTRLLQDSLGGNS T+
Sbjct: 133 GLLALGNVISALGEDVQKRGHIPYRDSKLTRLLQDSLGGNSHTL 2
>28434
          Length = 777

 Score =  172 bits (436), Expect = 9e-43,   Method: Compositional matrix adjust.
 Identities = 85/147 (57%), Positives = 111/147 (75%)
 Frame = +2

Query: 256 ESSPMNEFETLTAKFHFVDLAGSERLKRTGATGERAKEGISINCGLLALGNVISALGDKS 315
           +S  M    T+     + DLAGSER KRT A G+R KEG++IN GLLALGNVISALG+  
Sbjct: 8   KSKKMTRTTTVWPSSTW*DLAGSERAKRTRAEGDRFKEGVNINRGLLALGNVISALGEDV 187

Query: 316 KRATHVPYRDSKLTRLLQDSLGGNSQTIMIACVSPSDRDFMETLNTLKYANRARNIKNKV 375
           ++  H+PYRDSKLTRLLQDSLGGNS T+M+ACVSP+D +  ETLNTL+YA+RAR IKNK 
Sbjct: 188 QKRGHIPYRDSKLTRLLQDSLGGNSHTLMVACVSPADSNMEETLNTLRYADRARKIKNKP 367

Query: 376 MVNQDRASQQINALRSEITRLQMELME 402
           ++N+D  S +I  LR  +  LQ+++++
Sbjct: 368 VINRDPQSDEILRLRQVVQSLQLQILQ 448
>12048
          Length = 1162

 Score =  152 bits (385), Expect = 8e-37,   Method: Compositional matrix adjust.
 Identities = 111/333 (33%), Positives = 168/333 (50%), Gaps = 5/333 (1%)
 Frame = +2

Query: 49  FTFDYVFDIDSQQEQIYTQCIEKLIEGC--FEGYNATVFAY---GQTGAGKTYTMGTGFD 103
           F FD  FD    Q+Q   +C  ++         + AT+  Y    + G GKT+T+  G +
Sbjct: 284 FRFDKCFD----QKQTKMKC-SRM*PSLS*TTSFKATMGQYSLMARRGGGKTFTITGGAE 448

Query: 104 VNIMEEEQGIISRAVRHLFKSIDEKKTSAIKNGLPPPEFKVNAQFLELYNEEVLDLFDTT 163
             +   ++G+I R++ ++++  ++          P   F V+  +LE+YN+   DL D  
Sbjct: 449 RYM---DRGLIPRSLSYIYEQTEKN---------PELSFTVHISYLEIYNDSGYDLLDPK 592

Query: 164 RDIDAKNKKSNIRIHEDSTGGIYTVGVTTRTVNTEPEMMQCLKLGALSRTTASTQMNVQS 223
            +         + + EDS   I+   ++    N+E E +  L LG  +R  A T MN  S
Sbjct: 593 HEAAKLEDLPKVNLLEDSDQNIHLRNLSVHQANSEEEALNLLFLGDTNRMIAETPMNQAS 772

Query: 224 SRSHAIFTIHVCQTRVCPQTDAENATDNKLISESSPMNEFETLTAKFHFVDLAGSERLKR 283
           SRSH IFTIH+  TR     +  +AT  +               AK+H VDLAGSER+ +
Sbjct: 773 SRSHCIFTIHIT-TR-----ETGSATIRR---------------AKYHLVDLAGSERVAK 889

Query: 284 TGATGERAKEGISINCGLLALGNVISALGDKSKRATHVPYRDSKLTRLLQDSLGGNSQTI 343
           T   G+   E   IN  L  L  VI AL +KS++  HVPYR+S +T +L+DSLGGN  T 
Sbjct: 890 TNVNGQLLTEARYINSSLHFLELVIIALSEKSRQ--HVPYRNSMMTSVLRDSLGGNCMTT 1063

Query: 344 MIACVSPSDRDFMETLNTLKYANRARNIKNKVM 376
           MIA  S   R+  E+++T ++A R   IKN V+
Sbjct: 1064MIATCSMEKRNMDESISTCRFAQRVAMIKNDVL 1162
>38050
          Length = 809

 Score = 65.5 bits (158), Expect(3) = 4e-31,   Method: Compositional matrix adjust.
 Identities = 30/61 (49%), Positives = 45/61 (73%)
 Frame = -3

Query: 337 GGNSQTIMIACVSPSDRDFMETLNTLKYANRARNIKNKVMVNQDRASQQINALRSEITRL 396
           G NS+TIM+A +SP+D ++ ETL+TL+YA+RA+ IK K MVN+D   + I  L+ E  +L
Sbjct: 300 GWNSKTIMVAALSPADINYEETLSTLRYADRAKQIKTKAMVNEDPTDKLIRELQEENDKL 121

Query: 397 Q 397
           +
Sbjct: 120 K 118

 Score = 56.2 bits (134), Expect(3) = 4e-31,   Method: Composition-based stats.
 Identities = 29/55 (52%), Positives = 40/55 (72%), Gaps = 1/55 (1%)
 Frame = -1

Query: 288 GERAKEGISINCGLLALGNVISALGDKS-KRATHVPYRDSKLTRLLQDSLGGNSQ 341
           G+R KEG +IN  L  LGN ISAL DK+  +   VP+RDS LT+LL+++LGG ++
Sbjct: 449 GDRLKEGAAINQSLSCLGNCISALADKAGGKNVKVPFRDSALTKLLKNALGGTAR 285

 Score = 53.9 bits (128), Expect(3) = 4e-31,   Method: Compositional matrix adjust.
 Identities = 41/124 (33%), Positives = 58/124 (46%)
 Frame = -2

Query: 171 KKSNIRIHEDSTGGIYTVGVTTRTVNTEPEMMQCLKLGALSRTTASTQMNVQSSRSHAIF 230
           KK  +RI +    G Y  G+    V +  ++ + ++ G  +RT A+T MN  SSR+H I 
Sbjct: 745 KKGGLRIRQHPKNGFYADGLQVVPVVSYEDIEKKMEAGTTNRTVAATNMNATSSRAHTIV 566

Query: 231 TIHVCQTRVCPQTDAENATDNKLISESSPMNEFETLTAKFHFVDLAGSERLKRTGATGER 290
            I   Q         +NA             E  T +A  + VDLAGSER   TGATG  
Sbjct: 565 GITFMQ-------KFKNA-----------AGEETTKSALINLVDLAGSERADSTGATGTD 440

Query: 291 AKEG 294
            ++G
Sbjct: 439 *RKG 428
>17748
          Length = 621

 Score = 78.6 bits (192), Expect(2) = 5e-30,   Method: Compositional matrix adjust.
 Identities = 51/139 (36%), Positives = 74/139 (53%), Gaps = 2/139 (1%)
 Frame = -3

Query: 77  FEGYNATVFAYGQTGAGKTYTMGTGFDVNIM--EEEQGIISRAVRHLFKSIDEKKTSAIK 134
           F+GYNATV AYGQTG+GKT++MG  ++ ++   EE  GII R ++ LF  I E+      
Sbjct: 373 FKGYNATVLAYGQTGSGKTFSMGGCYEASLKLDEEAMGIIPRIIKDLFNGIQER------ 212

Query: 135 NGLPPPEFKVNAQFLELYNEEVLDLFDTTRDIDAKNKKSNIRIHEDSTGGIYTVGVTTRT 194
              P   FKV   +LE+YNEE          +   +++  + I E+  G I   G+   T
Sbjct: 211 ---PDHTFKVTVSYLEIYNEE------LLBLLCPLSQRQPLTIREELNGEIKIKGLKEVT 59

Query: 195 VNTEPEMMQCLKLGALSRT 213
           V +  + + CL  GA  RT
Sbjct: 58  VGSVDDTLDCLSQGAQLRT 2

 Score = 72.8 bits (177), Expect(2) = 5e-30,   Method: Composition-based stats.
 Identities = 33/68 (48%), Positives = 42/68 (61%)
 Frame = -2

Query: 10  VRVAVRIRPQLAKEKIEGCHICTSVTPGEPQVFLGKDKAFTFDYVFDIDSQQEQIYTQCI 69
           VRVA+R RP +AKE+ EGC  C      +PQV LGKDK FTFDYVF     Q+ +Y +  
Sbjct: 575 VRVALRARPLIAKEESEGCQTCLWYNSSQPQVVLGKDKPFTFDYVFSPKHNQQDVYEKSA 396

Query: 70  EKLIEGCF 77
           + L+   F
Sbjct: 395 QTLVTSTF 372
>13148
          Length = 653

 Score = 92.4 bits (228), Expect(2) = 3e-27,   Method: Composition-based stats.
 Identities = 66/194 (34%), Positives = 92/194 (47%), Gaps = 3/194 (1%)
 Frame = -3

Query: 108 EEEQGIISRAVRHLFKSI---DEKKTSAIKNGLPPPEFKVNAQFLELYNEEVLDLFDTTR 164
           E  QGII R V+ +F  I   DE             EF +   + E+Y +++ DL D T 
Sbjct: 468 ESLQGIIPRIVQDIFNYIYGMDENL-----------EFHIKVSYFEIYMDKIRDLLDVT- 325

Query: 165 DIDAKNKKSNIRIHEDSTGGIYTVGVTTRTVNTEPEMMQCLKLGALSRTTASTQMNVQSS 224
                  K+N+ +HED     Y  G T R V++  E+M+ +  G  +R  A T MN  SS
Sbjct: 324 -------KTNLSVHEDKNRVPYVKGCTERFVSSPEEVMEVVDEGKSNRHVAVTNMNEHSS 166

Query: 225 RSHAIFTIHVCQTRVCPQTDAENATDNKLISESSPMNEFETLTAKFHFVDLAGSERLKRT 284
           RSH++F IHV Q  V    D+E                 + L  K + VDLAGSE++ +T
Sbjct: 165 RSHSVFLIHVKQENV----DSE-----------------KKLHGKLYLVDLAGSEKVSKT 49

Query: 285 GATGERAKEGISIN 298
           GA G    E  +IN
Sbjct: 48  GAEGAVLDEAKNIN 7

 Score = 49.7 bits (117), Expect(2) = 3e-27,   Method: Composition-based stats.
 Identities = 21/50 (42%), Positives = 29/50 (58%)
 Frame = -1

Query: 45  KDKAFTFDYVFDIDSQQEQIYTQCIEKLIEGCFEGYNATVFAYGQTGAGK 94
           + K F FD V   +  QE +YT   + ++     GYN T+FAYGQT +GK
Sbjct: 647 RGKVFMFDKVLKPNVTQEYVYTVTAKPIVADVLSGYNGTIFAYGQTSSGK 498
>02896
          Length = 2076

 Score =  112 bits (280), Expect = 1e-24,   Method: Compositional matrix adjust.
 Identities = 74/223 (33%), Positives = 120/223 (53%), Gaps = 2/223 (0%)
 Frame = +1

Query: 185 IYTVGVTTRTVNTEPEMMQCLKLGALSRTTASTQMNVQSSRSHAIFTIHVCQTRVCPQTD 244
           +++ G+ +     E E +  L  G  +R+ A+  +N  SSRSH IFT+++ ++R   Q+ 
Sbjct: 10  LWSRGLASHLAQNEEEALNLLFEGETNRSIAAHSLNRMSSRSHCIFTVYL-ESRSRVQSS 186

Query: 245 AENATDNKLISESSPMNEFETLTAKFHFVDLAGSERLKRTGATGERAKEGISINCGLLAL 304
           A+                     +K +FVDLAGSER+ ++ + G+   E + IN  L  L
Sbjct: 187 AKYTV------------------SKLNFVDLAGSERIGKSKSEGKMVTEAMYINKSLSFL 312

Query: 305 GNVISALGDKSKRATHVPYRDSKLTRLLQDSLGGNSQTIMIACVSPSDRDFMETLNTLKY 364
             V+ AL DK++   H+P+R SKLT  L+DS+GGN  T++IA V        ET++TL++
Sbjct: 313 EQVVIALADKNR--DHIPFRQSKLTHYLKDSIGGNCNTVLIANVWGERAQLEETVSTLRF 486

Query: 365 ANRARNIKNKVMVNQ--DRASQQINALRSEITRLQMELMEYKT 405
           A R   + N+  +N+  D A   +  L+ EI  L+ EL  + T
Sbjct: 487 ATRMMCVANEPAINEVYDPA-LLVKKLQREINHLKAELAMHDT 612
>34477
          Length = 811

 Score =  105 bits (263), Expect = 1e-22,   Method: Compositional matrix adjust.
 Identities = 58/133 (43%), Positives = 81/133 (60%)
 Frame = +3

Query: 268 AKFHFVDLAGSERLKRTGATGERAKEGISINCGLLALGNVISALGDKSKRATHVPYRDSK 327
            K H VDLAGSER  +TGATG+R KE   IN  L  LGNVIS  G + +  TH P ++ +
Sbjct: 195 GKLHLVDLAGSERQAKTGATGQRLKEATKINLSLSTLGNVISVPGGRQEH-TH-PLQELQ 368

Query: 328 LTRLLQDSLGGNSQTIMIACVSPSDRDFMETLNTLKYANRARNIKNKVMVNQDRASQQIN 387
                    G   QT+M+A + P+D ++ ET++TL+YANRA+NIKNK  +N+D     + 
Sbjct: 369 AHSPAAGLPGRQLQTVMVANMGPADYNYDETISTLRYANRAKNIKNKAKINEDPKDALLR 548

Query: 388 ALRSEITRLQMEL 400
             + EI  L+ +L
Sbjct: 549 QFQKEIEELRKQL 587

 Score = 65.5 bits (158), Expect = 2e-10,   Method: Composition-based stats.
 Identities = 53/159 (33%), Positives = 79/159 (49%), Gaps = 2/159 (1%)
 Frame = +1

Query: 185 IYTVGVTTRTVNTEPEMMQCLKLGALSRTTASTQMNVQSSRSHAIFTIHVCQTRVCPQTD 244
           +Y   ++   VN   +M + + LG  +R+  ST MN+ SSRSHAIFT+ V       +  
Sbjct: 1   VYVKDLSAFVVNNADDMDRIMTLGNKNRSVGSTNMNMHSSRSHAIFTVTV-------ECS 159

Query: 245 AENATDNKLISESSPMNEFETLTAKFHFVDLAGSERLKRT--GATGERAKEGISINCGLL 302
            + AT + +            + A   +    G     R    A+  R +   +  C L 
Sbjct: 160 EKGATGSSMY-----------VWANCTWWTWXGQRDKPRQEPQASA*RKRPRSTCLCQLW 306

Query: 303 ALGNVISALGDKSKRATHVPYRDSKLTRLLQDSLGGNSQ 341
           A+     +L D   ++TH+PYR+SKLTRLLQDSLGGNS+
Sbjct: 307 AM--*YRSLVD--GKSTHIPYRNSKLTRLLQDSLGGNSK 411
>15043
          Length = 973

 Score = 97.1 bits (240), Expect = 6e-20,   Method: Compositional matrix adjust.
 Identities = 64/196 (32%), Positives = 95/196 (48%)
 Frame = +2

Query: 202 MQCLKLGALSRTTASTQMNVQSSRSHAIFTIHVCQTRVCPQTDAENATDNKLISESSPMN 261
           +  L  G  +R   +T +    +R+HA+FTI V Q                   +SS + 
Sbjct: 8   LTAL*TGRRARRMGATDIKAHRARAHAVFTITVEQKE----------------RQSSKVG 139

Query: 262 EFETLTAKFHFVDLAGSERLKRTGATGERAKEGISINCGLLALGNVISALGDKSKRATHV 321
               + A    V+LAG E    T            I  G   + NV+ ALGD  +   HV
Sbjct: 140 ----VRANIMLVELAGCEAADATDP---------KILAGTQGVVNVLKALGDSKQIGGHV 280

Query: 322 PYRDSKLTRLLQDSLGGNSQTIMIACVSPSDRDFMETLNTLKYANRARNIKNKVMVNQDR 381
           PYR+S +TRLLQD+LGGN+ T+M+  VSP D+ +  T + L+Y   A+ +KN   +N D 
Sbjct: 281 PYRESLVTRLLQDTLGGNAMTLMLVTVSPLDKSYQTTQSALQYGQFAKTVKNHARMNLDD 460

Query: 382 ASQQINALRSEITRLQ 397
               I  +R +I+RL+
Sbjct: 461 TQDIIAEMRQDISRLR 508
>14618
          Length = 724

 Score = 94.4 bits (233), Expect = 4e-19,   Method: Compositional matrix adjust.
 Identities = 71/237 (29%), Positives = 120/237 (50%), Gaps = 22/237 (9%)
 Frame = -2

Query: 9   SVRVAVRIRPQLAKEKI--EGC--HI--------------CTSVTPGEPQVF---LGKDK 47
           ++RV  R+RP L +E    +G   HI               T ++  E  ++    G +K
Sbjct: 669 NIRVFCRVRPLLGEEAATNDGVIHHINFPDSDNKVLELDRLTEMSMNESTLYNNRRGNNK 490

Query: 48  A-FTFDYVFDIDSQQEQIYTQCIEKLIEGCFEGYNATVFAYGQTGAGKTYTMGTGFDVNI 106
             F+FD VF  D+ Q+ ++ + I +L++   +GYN  +FAYGQTG+GKTYTM  G   + 
Sbjct: 489 YEFSFDRVFHPDNTQQDVFEE-ISQLVQSALDGYNVCIFAYGQTGSGKTYTMEGGLVGD- 316

Query: 107 MEEEQGIISRAVRHLFKSIDEKKTSAIKNGLPPPEFKVNAQFLELYNEEVLDLFDTTRDI 166
            E+ +G+I RAV  +F +  E +           ++K    F+E+YNE + DL  + +  
Sbjct: 315 -EDTKGMIPRAVSQIFSTARELQDKGW-------QYKFTTSFVEIYNEMIGDLLSSNK-- 166

Query: 167 DAKNKKSNIRIHEDSTGGIYTVGVTTRTVNTEPEMMQCLKLGALSRTTASTQMNVQS 223
             KN K  IR+       +    +TT  V ++ E+ + L+  + +R  A+T+ N +S
Sbjct: 165 -XKNVKHEIRM-AGRDNNVAVTNLTTVDVTSQHEIAKLLRQASENRAVAATKCNERS 1
>30256
          Length = 961

 Score = 73.6 bits (179), Expect = 5e-13,   Method: Composition-based stats.
 Identities = 72/280 (25%), Positives = 112/280 (40%), Gaps = 2/280 (0%)
 Frame = +3

Query: 1237 QCVHIAEGHTKAVLCVDSTDDLLFTGSKDRTCKVWNLVTGQEIMSLGVHPNNVVSVKYCN 1296
            +C+    GHT  V     T + + +GS DR+ KVWN  TG    +L  H + V  +    
Sbjct: 15   RCIKNLIGHTGGVWSSQMTGNTVISGSTDRSLKVWNADTGVCTHTLYGHSSTVRCLSLSG 194

Query: 1297 YTSLVFTVSTSYIKVWDIRESAKCIRTLTSSGQVTLGEACSASTSRTVAIPSGESQINQI 1356
               +V     + ++VWDI ES  C+  L   G +           R V+           
Sbjct: 195  -KKVVSGSRDATLRVWDI-ESGHCLNVLL--GHMAAVRCVQYDGKRVVS----------- 329

Query: 1357 ALNPTGTFLYAASGNAVRMWDLKRFQSTGKLTGHLGPVMCLTVDQISNGQDLIITGSKDH 1416
                       A    VR+WD         L GH   V  L  D +      +++GS D 
Sbjct: 330  ----------GAXDYTVRVWDPDTASCLHTLQGHTNRVYSLQFDGV-----YVVSGSLDT 464

Query: 1417 YIKMFDVTEGALGTVSPTHNFEPPHYDGIEALAIQGDNLFSGSRDNGIKKWDLAQKGLLQ 1476
             I+++DV  G L      H     H      L ++ + L SG+ D+ +K WD+     LQ
Sbjct: 465  SIRVWDVRCGKL-----VHTLM-GHQSLTSGLELKDNLLVSGNADSTVKVWDVHTGKCLQ 626

Query: 1477 QV--PNAHKDWVCALGLVPGHPVLLSGCRGGILKLWNVDT 1514
             +  PN H+  V  L        +++    G +KLW+++T
Sbjct: 627  TLLGPNKHRSAVTCLQF--NKKFVVTCSDDGTVKLWDLNT 740

 Score = 68.6 bits (166), Expect = 2e-11,   Method: Composition-based stats.
 Identities = 62/254 (24%), Positives = 114/254 (44%), Gaps = 20/254 (7%)
 Frame = +3

Query: 1317 SAKCIRTLTS------SGQVTLGEACSASTSRTVAIPSGESQI----------NQIALNP 1360
            + +CI+ L        S Q+T     S ST R++ + + ++ +              L+ 
Sbjct: 9    TGRCIKNLIGHTGGVWSSQMTGNTVISGSTDRSLKVWNADTGVCTHTLYGHSSTVRCLSL 188

Query: 1361 TGTFLYAASGNA-VRMWDLKRFQSTGKLTGHLGPVMCLTVDQISNGQDLIITGSKDHYIK 1419
            +G  + + S +A +R+WD++       L GH+  V C+  D        +++G+ D+ ++
Sbjct: 189  SGKKVVSGSRDATLRVWDIESGHCLNVLLGHMAAVRCVQYDG-----KRVVSGAXDYTVR 353

Query: 1420 MFDVTEGALGTVSPTHNFEPPHYDGIEALAIQGDNLFSGSRDNGIKKWDLAQKGLLQQVP 1479
            ++D       T S  H  +  H + + +L   G  + SGS D  I+ WD+ + G L    
Sbjct: 354  VWDPD-----TASCLHTLQG-HTNRVYSLQFDGVYVVSGSLDTSIRVWDV-RCGKLVHTL 512

Query: 1480 NAHKDWVCALGLVPGHPVLLSGCRGGILKLWNVDTFVPVGEMRG---HDSPINAICVNST 1536
              H+     L L     +L+SG     +K+W+V T   +  + G   H S +  +  N  
Sbjct: 513  MGHQSLTSGLELKDN--LLVSGNADSTVKVWDVHTGKCLQTLLGPNKHRSAVTCLQFNKK 686

Query: 1537 HVFTAADDRTVRIW 1550
             V T +DD TV++W
Sbjct: 687  FVVTCSDDGTVKLW 728

 Score = 51.6 bits (122), Expect = 3e-06,   Method: Composition-based stats.
 Identities = 40/191 (20%), Positives = 85/191 (44%)
 Frame = +3

Query: 1363 TFLYAASGNAVRMWDLKRFQSTGKLTGHLGPVMCLTVDQISNGQDLIITGSKDHYIKMFD 1422
            T +  ++  ++++W+      T  L GH   V CL++    +G+  +++GS+D  ++++D
Sbjct: 78   TVISGSTDRSLKVWNADTGVCTHTLYGHSSTVRCLSL----SGKK-VVSGSRDATLRVWD 242

Query: 1423 VTEGALGTVSPTHNFEPPHYDGIEALAIQGDNLFSGSRDNGIKKWDLAQKGLLQQVPNAH 1482
            +  G         N    H   +  +   G  + SG+ D  ++ WD      L  +   H
Sbjct: 243  IESGH------CLNVLLGHMAAVRCVQYDGKRVVSGAXDYTVRVWDPDTASCLHTL-QGH 401

Query: 1483 KDWVCALGLVPGHPVLLSGCRGGILKLWNVDTFVPVGEMRGHDSPINAICVNSTHVFTAA 1542
             + V +L     +  ++SG     +++W+V     V  + GH S  + + +    + +  
Sbjct: 402  TNRVYSLQFDGVY--VVSGSLDTSIRVWDVRCGKLVHTLMGHQSLTSGLELKDNLLVSGN 575

Query: 1543 DDRTVRIWKAH 1553
             D TV++W  H
Sbjct: 576  ADSTVKVWDVH 608
>34899
          Length = 564

 Score = 69.3 bits (168), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 44/179 (24%), Positives = 85/179 (47%)
 Frame = +3

Query: 50  TFDYVFDIDSQQEQIYTQCIEKLIEGCFEGYNATVFAYGQTGAGKTYTMGTGFDVNIMEE 109
           + D  +  D++  QIY +  + +++   EGYN T+ A+G TG+GK++ M      N  ++
Sbjct: 3   SLDGAYGPDAKNGQIYQEKCDSMVQRALEGYNVTIMAFGATGSGKSFLM------NGNDQ 164

Query: 110 EQGIISRAVRHLFKSIDEKKTSAIKNGLPPPEFKVNAQFLELYNEEVLDLFDTTRDIDAK 169
           E G+    ++ LF+ + ++            E  V A F+E+ +E++ DL      ++  
Sbjct: 165 EIGVAPMVIQQLFQHLRQRSNK---------ESMVTASFVEILDEKMTDL------LNPH 299

Query: 170 NKKSNIRIHEDSTGGIYTVGVTTRTVNTEPEMMQCLKLGALSRTTASTQMNVQSSRSHA 228
           N+   +R H     GI+  G++     T  E+ Q  + G  +R   +T +    +R  A
Sbjct: 300 NRPMAVRQH--VIKGIFVDGLSEMVARTGEELSQLYEQGRRARRMGATDIKAHRARYDA 470
>00561
          Length = 1003

 Score = 63.5 bits (153), Expect = 6e-10,   Method: Composition-based stats.
 Identities = 55/219 (25%), Positives = 96/219 (43%), Gaps = 14/219 (6%)
 Frame = -3

Query: 1355 QIALNPTG--TFLYAASGNAVRMWDLKRFQSTG------KLTGHLGPVMCLTVDQISNGQ 1406
            QIA NP    T + A+    + +W L R + T       +L GH   +  +    +S+  
Sbjct: 998  QIATNPKDPDTIISASRDKTLIVWKLTRDEDTNYGYPQKRLYGHSHFISDVV---LSSDG 828

Query: 1407 DLIITGSKDHYIKMFDVTEGALGTVSPTHNFEPPHYDGIEALAIQGDN--LFSGSRDNGI 1464
            +  ++GS D  ++++D+  G       T  FE  H   + ++A   DN  + SGSRD  I
Sbjct: 827  NYALSGSWDQTLRLWDLAAG-----KTTRRFEG-HTKDVLSVAFSADNRQIVSGSRDKTI 666

Query: 1465 KKWDLAQKGLLQQVPNAHKDWVCALGLVPGH--PVLLSGCRGGILKLWNVDTFVPVGEMR 1522
            K W+   +       + H DWV  +   P H  P+++S      +K+WN+          
Sbjct: 665  KLWNTLAECKFTIQEDGHTDWVSCVRFSPNHSNPIIVSCGWDRTVKVWNLANCKLKNNHH 486

Query: 1523 GHDSPINAICV--NSTHVFTAADDRTVRIWKAHNLQDGQ 1559
            GH+  +N + V  + +   +   D    +W   +L DG+
Sbjct: 485  GHNGYLNTVTVSPDGSLCTSGGKDSKALLW---DLNDGK 378

 Score = 41.2 bits (95), Expect = 0.003,   Method: Composition-based stats.
 Identities = 44/166 (26%), Positives = 74/166 (44%), Gaps = 30/166 (18%)
 Frame = -3

Query: 1243 EGHTKAVLCVDSTDD--LLFTGSKDRTCKVWN-LVTGQEIMSLGVHPNNVVSVKYCNYTS 1299
            EGHTK VL V  + D   + +GS+D+T K+WN L   +  +    H + V  V++    S
Sbjct: 749  EGHTKDVLSVAFSADNRQIVSGSRDKTIKLWNTLAECKFTIQEDGHTDWVSCVRFSPNHS 570

Query: 1300 LVFTVSTSY---IKVWDIRESAKC------------IRTLTSSGQVTLGEACSASTSRTV 1344
                VS  +   +KVW++   A C            + T+T S     G  C++    + 
Sbjct: 569  NPIIVSCGWDRTVKVWNL---ANCKLKNNHHGHNGYLNTVTVSPD---GSLCTSGGKDSK 408

Query: 1345 A----IPSGESQ--------INQIALNPTGTFLYAASGNAVRMWDL 1378
            A    +  G++         IN +  +P   +L  A G ++++WDL
Sbjct: 407  ALLWDLNDGKNLYTLEHNDIINALCFSPNRYWLCVAYGPSIKIWDL 270

 Score = 29.6 bits (65), Expect = 9.8,   Method: Composition-based stats.
 Identities = 53/266 (19%), Positives = 100/266 (37%), Gaps = 10/266 (3%)
 Frame = -3

Query: 1257 DLLFTGSKDRTCKVWNLVTGQEIMSLGVHPNNVVSVKYCNYTSLVFTVSTSY-------- 1308
            D + + S+D+T  VW L T  E  + G +P   +       + +V +   +Y        
Sbjct: 971  DTIISASRDKTLIVWKL-TRDEDTNYG-YPQKRLYGHSHFISDVVLSSDGNYALSGSWDQ 798

Query: 1309 -IKVWDIRESAKCIRTLTSSGQVTLGEACSASTSRTVAIPSGESQINQIALNPTGTFLYA 1367
             +++WD+  + K  R      +  L  A SA   + V+                      
Sbjct: 797  TLRLWDL-AAGKTTRRFEGHTKDVLSVAFSADNRQIVS---------------------G 684

Query: 1368 ASGNAVRMWD-LKRFQSTGKLTGHLGPVMCLTVDQISNGQDLIITGSKDHYIKMFDVTEG 1426
            +    +++W+ L   + T +  GH   V C+     ++   +I++   D  +K++++   
Sbjct: 683  SRDKTIKLWNTLAECKFTIQEDGHTDWVSCVRFSP-NHSNPIIVSCGWDRTVKVWNLANC 507

Query: 1427 ALGTVSPTHNFEPPHYDGIEALAIQGDNLFSGSRDNGIKKWDLAQKGLLQQVPNAHKDWV 1486
             L      HN     Y     ++  G    SG +D+    WDL     L  +   H D +
Sbjct: 506  KLKNNHHGHN----GYLNTVTVSPDGSLCTSGGKDSKALLWDLNDGKNLYTL--EHNDII 345

Query: 1487 CALGLVPGHPVLLSGCRGGILKLWNV 1512
             AL   P     L    G  +K+W++
Sbjct: 344  NALCFSPNR-YWLCVAYGPSIKIWDL 270
>18792
          Length = 447

 Score = 56.6 bits (135), Expect = 7e-08,   Method: Compositional matrix adjust.
 Identities = 25/44 (56%), Positives = 35/44 (79%)
 Frame = +2

Query: 631 NYQADLANITCEIAIKQKLIDELENSQKRLQTLKKQYEEKLMML 674
           N   DLA +TCEI+IKQ+LI++LE S K +Q++K QYEEK++ L
Sbjct: 314 NIHEDLAELTCEISIKQRLIEDLERSNKHMQSMKMQYEEKVVQL 445
>17602
          Length = 481

 Score = 52.0 bits (123), Expect = 2e-06,   Method: Composition-based stats.
 Identities = 35/161 (21%), Positives = 75/161 (46%), Gaps = 4/161 (2%)
 Frame = +3

Query: 1269 KVWNLVTGQEIMSLGVHPNNVVSVKYCNYTSLVFTVSTSY---IKVWDIRESAKCIRTLT 1325
            ++W++ TG+ + +L  H + V +V +    SL+  VS+SY    ++WD   S +C+ TL 
Sbjct: 3    RIWDVKTGKCLKTLPAHSDPVTAVHFNRDGSLI--VSSSYDGLCRIWDT-ASGQCLXTL- 170

Query: 1326 SSGQVTLGEACSASTSRTVAIPSGESQINQIALNPTGTFLYAAS-GNAVRMWDLKRFQST 1384
                                I      ++ +  +P G ++ AA+  N +++WD  + +  
Sbjct: 171  --------------------IDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCL 290

Query: 1385 GKLTGHLGPVMCLTVDQISNGQDLIITGSKDHYIKMFDVTE 1425
                GH     C+  +    G   I++GS+D+ + ++++ +
Sbjct: 291  KTYVGHRNEKYCIFANFSVTGGKWIVSGSEDNMVYIWNLLD 413
>36593
          Length = 466

 Score = 52.0 bits (123), Expect = 2e-06,   Method: Composition-based stats.
 Identities = 24/41 (58%), Positives = 33/41 (80%)
 Frame = +1

Query: 327 KLTRLLQDSLGGNSQTIMIACVSPSDRDFMETLNTLKYANR 367
           KLT LLQ+SLGGNS+T+M   VSP + +F ETLN+L++A +
Sbjct: 1   KLTYLLQNSLGGNSKTLMFVNVSPKEENFSETLNSLRFATK 123
>19949
          Length = 903

 Score = 51.2 bits (121), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 43/149 (28%), Positives = 62/149 (41%), Gaps = 14/149 (9%)
 Frame = +2

Query: 1353 INQIALNPTGTFLYAASGNA---VRMWDLKRFQSTGKLTGHLGPVMCLTVDQISNGQDLI 1409
            +  +  +P G   Y ASG+    V++WD++R        GH G V CL   + S     I
Sbjct: 2    VKSLDFHPYGA--YTASGSMDCNVKLWDIRRKGCIYTYKGHTGCVCCL---RFSPDGRWI 166

Query: 1410 ITGSKDHYIKMFDVTEGALGTVSPTHNFEPPHYDGIEALAIQGDNLF--SGSRDNGIKKW 1467
             + S+D  +K++D+T G L T    H       D +  +          SGS D  +K W
Sbjct: 167  ASASEDGLVKLWDLTAGKLLTDLKLHR------DAVNTIEFHPHEFLLASGSADRTVKFW 328

Query: 1468 DLAQKGLLQQV-PNA--------HKDWVC 1487
            DL    L+    P A        H D VC
Sbjct: 329  DLETFQLISTTEPEANSIRSILFHPDGVC 415

 Score = 48.5 bits (114), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 31/103 (30%), Positives = 47/103 (45%), Gaps = 3/103 (2%)
 Frame = +2

Query: 1457 SGSRDNGIKKWDLAQKGLLQQVPNAHKDWVCALGLVPGHPVLLSGCRGGILKLWNVDTFV 1516
            SGS D  +K WD+ +KG +      H   VC L   P    + S    G++KLW++    
Sbjct: 44   SGSMDCNVKLWDIRRKGCIYTY-KGHTGCVCCLRFSPDGRWIASASEDGLVKLWDLTAGK 220

Query: 1517 PVGEMRGHDSPINAICVNSTHVFTAAD---DRTVRIWKAHNLQ 1556
             + +++ H   +N I  +  H F  A    DRTV+ W     Q
Sbjct: 221  LLTDLKLHRDAVNTIEFHP-HEFLLASGSADRTVKFWDLETFQ 346

 Score = 43.9 bits (102), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 41/172 (23%), Positives = 79/172 (45%), Gaps = 3/172 (1%)
 Frame = +2

Query: 1238 CVHIAEGHTKAVLCVDSTDD--LLFTGSKDRTCKVWNLVTGQEIMSLGVHPNNVVSVKYC 1295
            C++  +GHT  V C+  + D   + + S+D   K+W+L  G+ +  L +H + V ++++ 
Sbjct: 95   CIYTYKGHTGCVCCLRFSPDGRWIASASEDGLVKLWDLTAGKLLTDLKLHRDAVNTIEFH 274

Query: 1296 NYTSLVFTVSTS-YIKVWDIRESAKCIRTLTSSGQVTLGEACSASTSRTVAIPSGESQIN 1354
             +  L+ + S    +K WD+ E+ + I T       T  EA S               I 
Sbjct: 275  PHEFLLASGSADRTVKFWDL-ETFQLIST-------TEPEANS---------------IR 385

Query: 1355 QIALNPTGTFLYAASGNAVRMWDLKRFQSTGKLTGHLGPVMCLTVDQISNGQ 1406
             I  +P G  LY+ S + ++++  +  +    ++   G V  ++   ISN Q
Sbjct: 386  SILFHPDGVCLYSGSKDTLKVYHWEPLELYDTVSVPWGQVCDMS---ISNTQ 532

 Score = 33.9 bits (76), Expect = 0.47,   Method: Compositional matrix adjust.
 Identities = 28/91 (30%), Positives = 42/91 (46%), Gaps = 2/91 (2%)
 Frame = +2

Query: 1258 LLFTGSKDRTCKVWNLVTGQEIMSLGVHPNNVVSVKYCNYTSLVFTVSTSYIKV--WDIR 1315
            LL +GS DRT K W+L T Q I +     N++ S+ +      +++ S   +KV  W+  
Sbjct: 287  LLASGSADRTVKFWDLETFQLISTTEPEANSIRSILFHPDGVCLYSGSKDTLKVYHWEPL 466

Query: 1316 ESAKCIRTLTSSGQVTLGEACSASTSRTVAI 1346
            E       L  +  V  G+ C  S S T  I
Sbjct: 467  E-------LYDTVSVPWGQVCDMSISNTQLI 538
>03395
          Length = 2795

 Score = 50.1 bits (118), Expect = 8e-06,   Method: Composition-based stats.
 Identities = 46/209 (22%), Positives = 84/209 (40%), Gaps = 10/209 (4%)
 Frame = +2

Query: 1353 INQIALNPTGTFLYAASGNA-VRMWDLKRFQSTGKLTGHLGPVMC-----LTVDQISNGQ 1406
            +  IA+   GT L +  G   VR+WD+ +   TGK  G L   M      +T  QI    
Sbjct: 5    VTAIAVTSCGTKLVSGGGEGQVRVWDIVKDMLTGKTRGDLVANMKEHKGKVTAIQIHTND 184

Query: 1407 DLIITGSKDHYIKMFDVTEGALGTVSPTHNFEPPHYDGIEALAIQGDNL--FSGSRDNGI 1464
               ++ S D    ++D+       +   +          + +   G +L   +   D+ I
Sbjct: 185  RCCVSASTDGSTIIWDLITNTRSQIVLANTL-------FKCVCFGGKDLHILTSGTDHKI 343

Query: 1465 KKWDLAQKGLLQQVPNAHKDWVCALGLVPGHPVLLSGCRGGILKLWNVDTFVPVGEMRGH 1524
              W++   GLL+++  +    +  + +      +L+G    +LKLW  +         GH
Sbjct: 344  GYWEVGDGGLLRELEGSQTGAINTIDIDRDGQTILTGGEDSLLKLWRYNEGEVTHTGIGH 523

Query: 1525 DSPINA--ICVNSTHVFTAADDRTVRIWK 1551
             + I    IC N  ++ +  +D  + IWK
Sbjct: 524  SNQITKARICPNRHYIVSGGEDGALHIWK 610
>12806
          Length = 961

 Score = 48.9 bits (115), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 52/221 (23%), Positives = 93/221 (42%), Gaps = 15/221 (6%)
 Frame = +3

Query: 1355 QIALNPTGTFLYAAS-GNAVRMWDL------KRFQSTG----KLTGHLGPVMCLTVDQIS 1403
            Q+    T  FL +    N + +WDL         Q+ G     LTGH   +  L    +S
Sbjct: 24   QVVDGATKPFLISGGRDNNIIVWDL*PKKDGDEDQTWGVPRKTLTGHSHFISDLA---LS 194

Query: 1404 NGQDLIITGSKDHYIKMFDVTEGALGTVSPTHNFEPPHYDGIEALAIQGDN--LFSGSRD 1461
                  ++ S D  ++++D+ +G     S T  F   H   +  +A   DN  + SG RD
Sbjct: 195  ADSRFALSSSWDATLRLWDIKKG-----STTSRF-INHTRDVLTVAFSPDNRQIASGGRD 356

Query: 1462 NGIKKWDLAQKGLLQQVPNAHKDWVCALGLV--PGHPVLLSGCRGGILKLWNVDTFVPVG 1519
              +K W++  +       NAH DWV  +       +P+++S      +K+W+  T     
Sbjct: 357  KNLKIWNIMGECKYTVDANAHTDWVTCVRFHQDTKNPIVVSASNDKTIKVWDNHTMTLKN 536

Query: 1520 EMRGHDSPINAICVNSTHVFTAADDRTVRIWKAHNLQDGQL 1560
               GH + I A+ +++ ++ + + D     W   N+ +G  
Sbjct: 537  TFVGHKAQITALDMSTNYLVSGSKDGIAMTW---NVAEGSF 650
>26107
          Length = 1338

 Score = 48.1 bits (113), Expect = 3e-05,   Method: Composition-based stats.
 Identities = 82/338 (24%), Positives = 131/338 (38%), Gaps = 25/338 (7%)
 Frame = -3

Query: 1239 VHIAEGHTKAVLCVD--STDDLLFTGSKDRTCKVWNLVTGQEIMSLGVHPNNVVSVKYCN 1296
            VH    H  AV      S D    T S D+T  +W++ T  ++ +   H  +V SV  C 
Sbjct: 1108 VHRWXAHNNAVFDYSWISNDSQCLTASGDQTVALWDVETTTKVTTFIGHKCSVRSVASCP 929

Query: 1297 YT--SLVFTVSTSYIKVWDIRESAKCIRTLTSSGQVTLGEACSASTSRTVAIPSGESQIN 1354
             +           +I +WD R + K  R      QV   + C  S  ++   P+   +I+
Sbjct: 928  SSPAQCASGARDGHIMLWDSRVNKK--REHQPCSQVH--QVCPQSGHQSK--PAKHRRIH 767

Query: 1355 QIALNPTGTFLYAASGNAVRMWDLKRFQSTGKLTGHLGPVMCLTVDQISNGQDLIIT-GS 1413
            + A  P G      S                        V C+    +    +LII+ G+
Sbjct: 766  RAA-GPKGVMDTQQS------------------------VTCV----LYQTDNLIISSGA 674

Query: 1414 KDHYIKMFDVTEGALGTVS----PTHNFEPPHY----DGIEALAIQ--GDNLFSGSRDNG 1463
             D  +KM+D  +    T +    P H F+ P +     GI  + +      LF    DN 
Sbjct: 673  NDGCVKMWDTRKWYTNTTTSLPVPVHTFDYPGHMRRLKGIVTMCMDPWKSQLFVSYTDNK 494

Query: 1464 IKKWDLAQKGLLQQ--VPNAHKD--WVCALGLVPGHPVLLSGCRGGILKLWNVDTFVPVG 1519
            + ++ LA +    Q  V   H++  +     + P    LLSG       +W VD   P  
Sbjct: 493  VYRYQLAGQYREPQEYVYAGHRNDTFFVRCAISPDGKYLLSGSGRNTGVIWEVDK--PNK 320

Query: 1520 E---MRGHDSPINAICVNSTHV---FTAADDRTVRIWK 1551
                + GH   ++A+   ST V    T +DDR++RIW+
Sbjct: 319  RPLFLIGHTEDVSAVDWCSTDVCKLATVSDDRSLRIWR 206
>17598
          Length = 875

 Score = 47.8 bits (112), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 39/158 (24%), Positives = 73/158 (46%), Gaps = 6/158 (3%)
 Frame = +1

Query: 1409 IITGSKDHYIKMFDVTEGALGTVSPTHNFEPPHYDGIEALAIQGDN--LFSGSRDNGIKK 1466
            +++ S D  ++++D+ +G     + T  F     D + A+A   DN  + SG RD  +K 
Sbjct: 166  VLSSSWDATLRLWDIKKG-----NTTRRFISHTRDAL-AVAFSPDNRQIASGGRDKALKI 327

Query: 1467 WDLAQKGLLQQVPNAHKDWVCALGLV--PGHPVLLSGCRGGILKLWNVDTFVPVGEMRGH 1524
            W+   +       N+H+DWV  +        P+++S      +K+W+  T        GH
Sbjct: 328  WNTVGECKFTVDANSHQDWVTCVKFHQDAKSPLVVSASMDKTIKVWDNQTMTLKHTFVGH 507

Query: 1525 DSPINAI--CVNSTHVFTAADDRTVRIWKAHNLQDGQL 1560
             + INAI   + + ++ + + D  V  W   N+Q+G  
Sbjct: 508  KTQINAIDLALKTYYLASGSKDGIVMTW---NIQNGTF 612

 Score = 45.4 bits (106), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 43/184 (23%), Positives = 81/184 (44%), Gaps = 5/184 (2%)
 Frame = +1

Query: 1353 INQIALNPTGTFLYAASGNA-VRMWDLKRFQSTGKLTGHLGPVMCLTVDQISNGQDLIIT 1411
            ++ ++L+    ++ ++S +A +R+WD+K+  +T +   H    + +     S     I +
Sbjct: 130  VSDVSLSADSRYVLSSSWDATLRLWDIKKGNTTRRFISHTRDALAVA---FSPDNRQIAS 300

Query: 1412 GSKDHYIKMFDVTEGALGTVSPTHNFEPPHYDGIEALAIQGDN----LFSGSRDNGIKKW 1467
            G +D  +K+++       TV         H D +  +    D     + S S D  IK W
Sbjct: 301  GGRDKALKIWNTVGECKFTVDAN-----SHQDWVTCVKFHQDAKSPLVVSASMDKTIKVW 465

Query: 1468 DLAQKGLLQQVPNAHKDWVCALGLVPGHPVLLSGCRGGILKLWNVDTFVPVGEMRGHDSP 1527
            D  Q   L+     HK  + A+ L      L SG + GI+  WN+     +G++   D  
Sbjct: 466  D-NQTMTLKHTFVGHKTQINAIDLALKTYYLASGSKDGIVMTWNIQNGTFLGKIDC-DCE 639

Query: 1528 INAI 1531
            +NA+
Sbjct: 640  VNAV 651
>10162
          Length = 1629

 Score = 45.4 bits (106), Expect = 2e-04,   Method: Composition-based stats.
 Identities = 43/171 (25%), Positives = 74/171 (43%), Gaps = 3/171 (1%)
 Frame = +3

Query: 1248 AVLCVDSTDD--LLFTGSKDRTCKVWNLVTGQEIMSLGVHPNNVVSVKYCNYTSLVFTVS 1305
            A+LCVD + D  L+ +G  D T KV+N+ +G+   +     +     K  +  S+ F   
Sbjct: 375  AILCVDCSADNALIMSGCADATAKVFNVSSGKLXSAFNCAASQDSQDKDNSVESVAFCPV 554

Query: 1306 TSYIKVWDIRESAKCIRTLTSSGQVTLGEACSASTSRTVAIPSGESQINQIALNPTGTFL 1365
            + Y              T T+SG V + +  ++    +   P G   + ++  + +   L
Sbjct: 555  SPYAA------------TATNSGSVQVWDLPTSVARHSFQHPEG---VCKLQWSSSTALL 689

Query: 1366 YAAS-GNAVRMWDLKRFQSTGKLTGHLGPVMCLTVDQISNGQDLIITGSKD 1415
            Y A     +R+WD +   S   LTGH      L  D   +G  L ++GS+D
Sbjct: 690  YTACLDGVMRVWDARSGASKAVLTGHARNSCILDFDVTRDGTCL-VSGSED 839

 Score = 34.3 bits (77), Expect = 0.44,   Method: Composition-based stats.
 Identities = 25/122 (20%), Positives = 57/122 (46%), Gaps = 5/122 (4%)
 Frame = +3

Query: 1408 LIITGSKDHYIKMFDVTEGALGTV---SPTHNFEPPHYDGIEALAIQGDNLFSGSRDNG- 1463
            LI++G  D   K+F+V+ G L +    + + + +    + +E++A    + ++ +  N  
Sbjct: 411  LIMSGCADATAKVFNVSSGKLXSAFNCAASQDSQDKD-NSVESVAFCPVSPYAATATNSG 587

Query: 1464 -IKKWDLAQKGLLQQVPNAHKDWVCALGLVPGHPVLLSGCRGGILKLWNVDTFVPVGEMR 1522
             ++ WDL     + +    H + VC L       +L + C  G++++W+  +      + 
Sbjct: 588  SVQVWDLPTS--VARHSFQHPEGVCKLQWSSSTALLYTACLDGVMRVWDARSGASKAVLT 761

Query: 1523 GH 1524
            GH
Sbjct: 762  GH 767
>18981
          Length = 407

 Score = 45.1 bits (105), Expect = 2e-04,   Method: Composition-based stats.
 Identities = 36/119 (30%), Positives = 52/119 (43%), Gaps = 1/119 (0%)
 Frame = -2

Query: 1453 DNLF-SGSRDNGIKKWDLAQKGLLQQVPNAHKDWVCALGLVPGHPVLLSGCRGGILKLWN 1511
            DN+  S + D  ++ W L    LL  +   + D  C    + G  V+ SG     L +W 
Sbjct: 388  DNMIISAATDRTLRVWCLKNTCLLHTLRGHNDDVECVC--IYGRRVV-SGSWDKTLIVWE 218

Query: 1512 VDTFVPVGEMRGHDSPINAICVNSTHVFTAADDRTVRIWKAHNLQDGQLSDTGDLGEDI 1570
            VDT  PV ++ GH   I A+  +     + + D  VR W    L  GQ   T   G+DI
Sbjct: 217  VDTGRPVHQLHGHTEAITAVQFDEGKAVSGSADGDVRTWA---LDTGQCLLTMTTGQDI 50

 Score = 37.7 bits (86), Expect = 0.034,   Method: Composition-based stats.
 Identities = 22/92 (23%), Positives = 45/92 (48%)
 Frame = -2

Query: 1239 VHIAEGHTKAVLCVDSTDDLLFTGSKDRTCKVWNLVTGQEIMSLGVHPNNVVSVKYCNYT 1298
            +H   GH   V CV      + +GS D+T  VW + TG+ +  L  H   + +V++ +  
Sbjct: 319  LHTLRGHNDDVECVCIYGRRVVSGSWDKTLIVWEVDTGRPVHQLHGHTEAITAVQF-DEG 143

Query: 1299 SLVFTVSTSYIKVWDIRESAKCIRTLTSSGQV 1330
              V   +   ++ W + ++ +C+ T+T+   +
Sbjct: 142  KAVSGSADGDVRTWAL-DTGQCLLTMTTGQDI 50

 Score = 34.3 bits (77), Expect = 0.36,   Method: Composition-based stats.
 Identities = 28/103 (27%), Positives = 45/103 (43%)
 Frame = -2

Query: 1367 AASGNAVRMWDLKRFQSTGKLTGHLGPVMCLTVDQISNGQDLIITGSKDHYIKMFDVTEG 1426
            AA+   +R+W LK       L GH   V C+ +     G+  +++GS D  + +++V  G
Sbjct: 370  AATDRTLRVWCLKNTCLLHTLRGHNDDVECVCI----YGRR-VVSGSWDKTLIVWEVDTG 206

Query: 1427 ALGTVSPTHNFEPPHYDGIEALAIQGDNLFSGSRDNGIKKWDL 1469
                  P H     H + I A+        SGS D  ++ W L
Sbjct: 205  -----RPVHQLH-GHTEAITAVQFDEGKAVSGSADGDVRTWAL 95
>27465
          Length = 658

 Score = 44.7 bits (104), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 33/127 (25%), Positives = 56/127 (44%), Gaps = 3/127 (2%)
 Frame = -1

Query: 1259 LFTGSKDRTCKVWNLVTGQEIMSLGVHPNNVVSVKYCN-YTSLVFTVSTS-YIKVWDIRE 1316
              TGS DRTCK+W+  + +E+ +L  H N V ++ + N +   V T S     K+W   +
Sbjct: 316  FITGSYDRTCKIWDTASAEELHTLEGHRNVVYAIAFNNPFGDKVITGSFDKTCKLWSTAD 137

Query: 1317 SAKCIRTLTSSGQVTLGEACSASTSRTVAIPSGESQINQIALNPTGTFLYAASGN-AVRM 1375
              KC  TL                          ++I  ++ NP+ T +   S +   R+
Sbjct: 136  -GKCYHTLRGH----------------------TAEIVCVSFNPSSTLIATGSMDTTCRL 26

Query: 1376 WDLKRFQ 1382
            WD+++ Q
Sbjct: 25   WDVEKAQ 5

 Score = 43.1 bits (100), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 26/96 (27%), Positives = 49/96 (51%), Gaps = 4/96 (4%)
 Frame = -1

Query: 1228 CKGVRASPLQCVHIAEGHTKAVLCV---DSTDDLLFTGSKDRTCKVWNLVTGQEIMSLGV 1284
            CK    +  + +H  EGH   V  +   +   D + TGS D+TCK+W+   G+   +L  
Sbjct: 289  CKIWDTASAEELHTLEGHRNVVYAIAFNNPFGDKVITGSFDKTCKLWSTADGKCYHTLRG 110

Query: 1285 HPNNVVSVKYCNYTSLVFTVST-SYIKVWDIRESAK 1319
            H   +V V +   ++L+ T S  +  ++WD+ ++ +
Sbjct: 109  HTAEIVCVSFNPSSTLIATGSMDTTCRLWDVEKAQR 2
>38061
          Length = 206

 Score = 42.4 bits (98), Expect = 0.001,   Method: Composition-based stats.
 Identities = 18/28 (64%), Positives = 24/28 (85%)
 Frame = -3

Query: 344 MIACVSPSDRDFMETLNTLKYANRARNI 371
           ++ACVSP+D +  ETLNTL+YA+RAR I
Sbjct: 84  LVACVSPADSNMEETLNTLRYADRARKI 1
>11493
          Length = 535

 Score = 42.4 bits (98), Expect = 0.001,   Method: Composition-based stats.
 Identities = 42/166 (25%), Positives = 70/166 (42%), Gaps = 9/166 (5%)
 Frame = -2

Query: 1392 GPVMCLTVDQISNGQDLIITGSKDHYIKMFDVTE-GALGTVSPTHNFEPPHYDGIEALAI 1450
            G V+C     ISN    + TG K   +K++D+++ G    VS     +  +Y     L  
Sbjct: 477  GEVVCAVT--ISNPTKYVYTGGKG-CVKVWDISQPGNKNPVSQLDCLQRDNYIRSVKLLP 307

Query: 1451 QGDNLFSGSRDNGIKKWDLA------QKGLLQQVPNAHKDWVCALGLVPGHPVLLSGCRG 1504
             G  L  G   + +  WDLA      +  L    P  +     AL + P   V  S C  
Sbjct: 306  DGRTLIVGGEASNLSIWDLASPTPRIKAELTSAAPACY-----ALAISPDSKVCFSCCSD 142

Query: 1505 GILKLWNVDTFVPVGEMRGHDSPINAICV--NSTHVFTAADDRTVR 1548
            G + +W++   + V + +GH    + I +  + + ++T   D TVR
Sbjct: 141  GNIAVWDLHNEILVRQFQGHTDGASCIDISPDGSRLWTGGLDNTVR 4

 Score = 31.2 bits (69), Expect = 3.6,   Method: Composition-based stats.
 Identities = 22/99 (22%), Positives = 45/99 (45%), Gaps = 8/99 (8%)
 Frame = -2

Query: 1464 IKKWDLAQKG---LLQQVPNAHKD-WVCALGLVPGHPVLLSGCRGGILKLWNVDTFVP-- 1517
            +K WD++Q G    + Q+    +D ++ ++ L+P    L+ G     L +W++ +  P  
Sbjct: 408  VKVWDISQPGNKNPVSQLDCLQRDNYIRSVKLLPDGRTLIVGGEASNLSIWDLASPTPRI 229

Query: 1518 VGEMRGHDSPINAICV--NSTHVFTAADDRTVRIWKAHN 1554
              E+        A+ +  +S   F+   D  + +W  HN
Sbjct: 228  KAELTSAAPACYALAISPDSKVCFSCCSDGNIAVWDLHN 112
>13335
          Length = 863

 Score = 42.0 bits (97), Expect = 0.002,   Method: Composition-based stats.
 Identities = 54/235 (22%), Positives = 92/235 (39%), Gaps = 18/235 (7%)
 Frame = +1

Query: 1305 STSYIKVWDIRESAKCIRTLTSSGQVTLGEACSASTSRTVAIPSGESQINQIALNPTGTF 1364
            S S I+V     S+  + + +    + + E  +    R+      E  +  +A +P G +
Sbjct: 58   SKSSIRVCKFSPSSSHLVSGSDDDTICMWEVATQKLVRSYV--GHEDSVMALAYSPNGHY 231

Query: 1365 LYAASGNA-VRMWDLKRFQS---TGKLTGH-LGPVMC--------LTVDQISNGQDLIIT 1411
            L + S N  + +WD         T ++  H LG   C           +  S    L+ T
Sbjct: 232  LVSGSPNGDLYVWDASFGHCRHLTLRVDAHDLGVTCCEFSPTFGTACAENSSTCNLLLAT 411

Query: 1412 GSKDHYIKM--FDVTEGALGTVSPTHNFEPPHYDGIEALAIQGDN--LFSGSRDNGIKKW 1467
            G KD+ IK+  F    G+        +    H D + A A    +  L SGS D  ++ W
Sbjct: 412  GGKDNLIKLWTFSAQVGSPEVTLQCRDILSGHSDLVMACAFSPSSALLASGSFDKSVRLW 591

Query: 1468 DLAQKGLLQQVPNAHKDWVCALGLVPGHPVLLSGCRGGILKLWNV-DTFVPVGEM 1521
            D  +   L  +   H  +V          +L SG    I+K+W + DT   +G++
Sbjct: 592  DSVKGVALFSIEACHSRFVTCCAFSIDGTLLASGSMDRIIKIWKLTDTSSIMGKL 756

 Score = 41.6 bits (96), Expect = 0.003,   Method: Composition-based stats.
 Identities = 55/226 (24%), Positives = 92/226 (40%), Gaps = 22/226 (9%)
 Frame = +1

Query: 1348 SGESQINQIALNPTGTFLYAASGN-AVRMWDLKRFQSTGKLTGHLGPVMCLTVDQISNGQ 1406
            + +S I     +P+ + L + S +  + MW++   +      GH   VM L      NG 
Sbjct: 55   ASKSSIRVCKFSPSSSHLVSGSDDDTICMWEVATQKLVRSYVGHEDSVMALAYS--PNGH 228

Query: 1407 DLIITGSKDHYIKMFDVTEGA---LGTVSPTHNFE------PPHYDGIEALAIQGDNLF- 1456
             L+ +GS +  + ++D + G    L      H+         P +    A      NL  
Sbjct: 229  YLV-SGSPNGDLYVWDASFGHCRHLTLRVDAHDLGVTCCEFSPTFGTACAENSSTCNLLL 405

Query: 1457 -SGSRDNGIKKWDL-AQKG----LLQ--QVPNAHKDWVCALGLVPGHPVLLSGCRGGILK 1508
             +G +DN IK W   AQ G     LQ   + + H D V A    P   +L SG     ++
Sbjct: 406  ATGGKDNLIKLWTFSAQVGSPEVTLQCRDILSGHSDLVMACAFSPSSALLASGSFDKSVR 585

Query: 1509 LWNVDTFVPVGEMRGHDSPINAIC---VNSTHVFTAADDRTVRIWK 1551
            LW+    V +  +    S     C   ++ T + + + DR ++IWK
Sbjct: 586  LWDSVKGVALFSIEACHSRFVTCCAFSIDGTLLASGSMDRIIKIWK 723
>21105
          Length = 650

 Score = 40.4 bits (93), Expect = 0.005,   Method: Composition-based stats.
 Identities = 27/91 (29%), Positives = 45/91 (49%), Gaps = 2/91 (2%)
 Frame = +1

Query: 1408 LIITGSKDHYIKMFDVTEGALGTVSPTHNFEPPHYDGIEALAIQGDNLF--SGSRDNGIK 1465
            + IT  +D +I+ FD   G L      H     H D + +LA+  + L+  SGS D  I+
Sbjct: 106  ITITAHEDRHIRFFDNNTGKL-----IHAM-VAHLDSVTSLAVDPNGLYLLSGSHDCSIR 267

Query: 1466 KWDLAQKGLLQQVPNAHKDWVCALGLVPGHP 1496
             W+L  K  +Q++ +  K +  ++  V  HP
Sbjct: 268  LWNLDSKTCVQEITSHRKKFDESIHDVAFHP 360

 Score = 33.9 bits (76), Expect = 0.58,   Method: Composition-based stats.
 Identities = 26/92 (28%), Positives = 43/92 (46%), Gaps = 6/92 (6%)
 Frame = +1

Query: 1481 AHKDWVCALGLVPGHPVLLSGCRGGILKLWNVDTFVPVGEMRGH----DSPINAICVN-- 1534
            AH D V +L + P    LLSG     ++LWN+D+   V E+  H    D  I+ +  +  
Sbjct: 184  AHLDSVTSLAVDPNGLYLLSGSHDCSIRLWNLDSKTCVQEITSHRKKFDESIHDVAFHPQ 363

Query: 1535 STHVFTAADDRTVRIWKAHNLQDGQLSDTGDL 1566
              ++ +A  D   +++  H      LS  GD+
Sbjct: 364  KPYIASAGADALAKVFV*HQPPLD*LSALGDV 459
>37180
          Length = 681

 Score = 39.7 bits (91), Expect = 0.009,   Method: Composition-based stats.
 Identities = 21/81 (25%), Positives = 42/81 (51%), Gaps = 2/81 (2%)
 Frame = +1

Query: 1478 VPNAHKDWVCALGLVPGHPVLLSGCRGGILKLWNV-DTFVPVGEMRGHDSPI-NAICVNS 1535
            V N H   +  +   P   ++++  +    +LW+  D+ + V   +GH  P+ +A+  + 
Sbjct: 4    VLNGHDQELSDVHAHPTQRLVVTSSKDMTFRLWDFRDSALLVNVFQGHTQPVTSAVFASG 183

Query: 1536 THVFTAADDRTVRIWKAHNLQ 1556
              V + +DDRTVR+W   N++
Sbjct: 184  DKVVSGSDDRTVRVWDMRNMR 246

 Score = 33.1 bits (74), Expect(2) = 0.075,   Method: Composition-based stats.
 Identities = 19/64 (29%), Positives = 32/64 (50%)
 Frame = +1

Query: 1406 QDLIITGSKDHYIKMFDVTEGALGTVSPTHNFEPPHYDGIEALAIQGDNLFSGSRDNGIK 1465
            Q L++T SKD   +++D  + AL       + +P       A+   GD + SGS D  ++
Sbjct: 55   QRLVVTSSKDMTFRLWDFRDSALLVNVFQGHTQPV----TSAVFASGDKVVSGSDDRTVR 222

Query: 1466 KWDL 1469
             WD+
Sbjct: 223  VWDM 234

 Score = 22.7 bits (47), Expect(2) = 0.075,   Method: Composition-based stats.
 Identities = 9/14 (64%), Positives = 10/14 (71%)
 Frame = +2

Query: 1487 CALGLVPGHPVLLS 1500
            CAL L P  P+LLS
Sbjct: 242  CALPLPPSAPILLS 283

 Score = 31.2 bits (69), Expect = 3.9,   Method: Composition-based stats.
 Identities = 14/36 (38%), Positives = 25/36 (69%), Gaps = 1/36 (2%)
 Frame = +1

Query: 1239 VHIAEGHTKAVL-CVDSTDDLLFTGSKDRTCKVWNL 1273
            V++ +GHT+ V   V ++ D + +GS DRT +VW++
Sbjct: 127  VNVFQGHTQPVTSAVFASGDKVVSGSDDRTVRVWDM 234
>27806
          Length = 419

 Score = 38.5 bits (88), Expect = 0.021,   Method: Composition-based stats.
 Identities = 20/72 (27%), Positives = 36/72 (50%), Gaps = 2/72 (2%)
 Frame = -1

Query: 1493 PGHPVLLSGCRGGILKLWNVDTFVPVGEMRGHDSPINAICVNSTH--VFTAADDRTVRIW 1550
            PGHP++ +       ++++++T   V    GH   +NA+  +     V TA+ D T  +W
Sbjct: 395  PGHPIIGTASADHTARIYSIETGACVLTYGGHQGSVNAVRFHPGQDLVLTASGDHTAHVW 216

Query: 1551 KAHNLQDGQLSD 1562
            +A   Q   +SD
Sbjct: 215  RAQFSQPSLMSD 180
>01462
          Length = 995

 Score = 38.1 bits (87), Expect = 0.032,   Method: Compositional matrix adjust.
 Identities = 31/127 (24%), Positives = 52/127 (40%), Gaps = 1/127 (0%)
 Frame = +2

Query: 1259 LFTGSKDRTCKVWNLVTGQEIMSLGVHPNNVVSVKYCNYTSLVFTVS-TSYIKVWDIRES 1317
            L+ G+ DR   VW++  GQ + ++  H + +  V   N      + S    +++WDIR S
Sbjct: 242  LYAGAGDRKIHVWDIEAGQYLNAMEGHKDYIHKVVMKNDAQECVSASEDGTVRMWDIRSS 421

Query: 1318 AKCIRTLTSSGQVTLGEACSASTSRTVAIPSGESQINQIALNPTGTFLYAASGNAVRMWD 1377
             + +  L  S      E CS         P     +  +AL+P   +L    G  +  W 
Sbjct: 422  TETVHCLEPSKN----ELCSR--------PLLGKWLRCLALDPEEGWLVCGGGPKLSAWH 565

Query: 1378 LKRFQST 1384
            L+    T
Sbjct: 566  LRTLAPT 586
>02147
          Length = 1547

 Score = 37.7 bits (86), Expect = 0.037,   Method: Compositional matrix adjust.
 Identities = 32/106 (30%), Positives = 51/106 (48%), Gaps = 3/106 (2%)
 Frame = +2

Query: 1457 SGSRDNGIKKWDLAQKGLLQQVPNAHKDWVCALGLVPGHPVLLSGCRGGILKLWN-VDTF 1515
            +G+ D   K WD A+KG   Q   +HK  V ++        LL+G    +LK+++ V+T 
Sbjct: 224  TGAADFSAKIWD-AEKGEELQT-FSHKHIVKSVDFSHDGTALLTGSNEKLLKVFDLVNTD 397

Query: 1516 VPVGEMRGHDSPINA--ICVNSTHVFTAADDRTVRIWKAHNLQDGQ 1559
                   GH S I       +   + +A+DD+TVR+W     Q+ Q
Sbjct: 398  AEPKSFAGHTSNIKGALFLSDGKRIISASDDKTVRLWSLETCQEVQ 535

 Score = 32.0 bits (71), Expect = 2.2,   Method: Compositional matrix adjust.
 Identities = 51/229 (22%), Positives = 89/229 (38%), Gaps = 63/229 (27%)
 Frame = +2

Query: 1261 TGSKDRTCKVWNLVTGQEIMSLGVHPNNVVSVKYCNYTSLVFTVST-SYIKVWDIRES-- 1317
            TG+ D + K+W+   G+E+ +   H + V SV + +  + + T S    +KV+D+  +  
Sbjct: 224  TGAADFSAKIWDAEKGEELQTFS-HKHIVKSVDFSHDGTALLTGSNEKLLKVFDLVNTDA 400

Query: 1318 -AKCIRTLTSS--GQVTLGEA---CSASTSRTVAIPSGES--QINQIALN--PTGTFL-- 1365
              K     TS+  G + L +     SAS  +TV + S E+  ++ Q+  +  PT   L  
Sbjct: 401  EPKSFAGHTSNIKGALFLSDGKRIISASDDKTVRLWSLETCQEVQQLTFDTPPTSLTLSP 580

Query: 1366 --------------------------------------------YAASGNAVRMWDLKRF 1381
                                                        + A G   +M+     
Sbjct: 581  DKNTIIVTHSQNIAFYQADTLREMKKFEAEAPISSASLHQSERFFVAGGEDFKMYKFD-- 754

Query: 1382 QSTGK----LTGHLGPVMCLTVDQISNGQDLIITGSKDHYIKMFDVTEG 1426
              TGK      GH GPV C+   + S   +L  +GS+D  ++++  T G
Sbjct: 755  YETGKEIESFKGHFGPVHCV---RFSPDGELYASGSEDGTLRLWQTTIG 892
>22114
          Length = 1140

 Score = 37.7 bits (86), Expect = 0.038,   Method: Compositional matrix adjust.
 Identities = 46/208 (22%), Positives = 86/208 (41%), Gaps = 26/208 (12%)
 Frame = -3

Query: 1241 IAEGHTKAVLCVD-STDDLLFTGSKDRTCKVWNL-VTGQEIMSLGVHPNN-------VVS 1291
             A  HT  +  +  ++D   +  + D    +WNL VT Q    + + P N       + +
Sbjct: 835  FANAHTYHINSISVNSDQETYLSADDLRVNLWNLEVTNQSFNIVDIKPANMEELTEVITA 656

Query: 1292 VKY----CNYTSLVFTVSTSYIKVWDIRESAKCIRTLTSSGQVTLGEACSASTSRTVAIP 1347
             ++    C  +S V++ S   I++ D+R  A C +         L E     T+R+    
Sbjct: 655  AEFHPNMC--SSFVYSSSKGSIRLCDMRNQALCDK------HAKLFEEPEDPTNRSF-FS 503

Query: 1348 SGESQINQIALNPTGTFLYAASGNAVRMWDL---KRFQSTGKLTGHLGPVMC------LT 1398
               S I+ +  +  G ++      +V++WDL    R   T ++  +L   +C        
Sbjct: 502  EIISSISDVKFSHDGRYMMTRDYLSVKLWDLAMESRPVETFQVHEYLRSKLCSLYENDCI 323

Query: 1399 VDQI----SNGQDLIITGSKDHYIKMFD 1422
             D+     S     I+TGS +++ +MFD
Sbjct: 322  FDKFECSWSADDRHIMTGSYNNFFRMFD 239
>02960
          Length = 1577

 Score = 37.0 bits (84), Expect = 0.058,   Method: Compositional matrix adjust.
 Identities = 39/135 (28%), Positives = 66/135 (48%), Gaps = 4/135 (2%)
 Frame = +2

Query: 1371 NAVRMWDLKRFQSTGKLTGHLGPVMCLTVDQISNGQDLIITGSKDHYIKMFD--VTEGAL 1428
            +++R+WDL   Q T  + G    V+ +    +S+   ++ITGS D ++++ D   +EG  
Sbjct: 1022 HSLRLWDLHTAQQTSLIQGSKA-VLDVAYSPLSH---MLITGSADRHVRLVDPRCSEGE- 1186

Query: 1429 GTVSPTHNFEPPHYDGIEALAIQGDNLFSGSRDNGIKKWDL-AQKGLLQQVPNAHKDWVC 1487
             TV            G++    +     SGS DN +K WD  + K  L  + N H+D + 
Sbjct: 1187 -TVKCAFTSHTGWVTGVDWSPTREHLFLSGSYDNVLKLWDTRSPKATLYDM-NWHEDRIL 1360

Query: 1488 ALGL-VPGHPVLLSG 1501
            A+   +P   +LLSG
Sbjct: 1361 AVDWSIP--ELLLSG 1399

 Score = 31.6 bits (70), Expect = 2.7,   Method: Compositional matrix adjust.
 Identities = 47/215 (21%), Positives = 80/215 (37%), Gaps = 15/215 (6%)
 Frame = +2

Query: 1361 TGTFLYAASGNAVRMWDLKRFQSTGKLTGHLGPVMCLTV---DQISNGQDLIITGSKDHY 1417
            TG  L  +  N VR+W  K  ++   + GH  PV C+     D+ S+G    +TGS D  
Sbjct: 515  TGXXLSGSYDNTVRLWSTKG-EAIMTIPGHTSPVKCVAWIKHDE-SSGVSTFVTGSHDQT 688

Query: 1418 IKMF---------DVTEGALGTVSPTHNFEPPHYDGIEALAIQGDN--LFSGSRDNGIKK 1466
              ++         D      G           H   ++ +A+  D+  + +GS D  +K 
Sbjct: 689  ALVWQWQRETNEVDCRLSCRG-----------HAASVDCVAVSPDSQQMCTGSWDKMLKL 835

Query: 1467 WDLAQKGLLQQVPNAHKDWVCALGLVPGHPVLLSGCRGGILKLWNVDTFVPVGEMRGHDS 1526
            W         Q  +  +            P           +     T VPV  + GH  
Sbjct: 836  WSTDCNVDGDQSEDTER------------PSKKKKSAKSTTQ-----TRVPVLTLSGHAE 964

Query: 1527 PINAI-CVNSTHVFTAADDRTVRIWKAHNLQDGQL 1560
             ++A+  ++   V T++ D ++R+W  H  Q   L
Sbjct: 965  AVSAVRWLDPHRVVTSSWDHSLRLWDLHTAQQTSL 1069
>02090
          Length = 1841

 Score = 36.6 bits (83), Expect = 0.075,   Method: Composition-based stats.
 Identities = 30/114 (26%), Positives = 48/114 (42%), Gaps = 8/114 (7%)
 Frame = -3

Query: 1467 WDLA------QKGLLQQVPNAHKDWVCALGLVPGHPVLLSGCRGGILKLWNVDTFVPVGE 1520
            WDLA      +  L    P  +     AL + P   V  S C  G + +W++     V +
Sbjct: 1677 WDLATPTPRIKAELTSSAPACY-----ALAISPDGKVCFSCCSDGNIAVWDLHNQTLVRQ 1513

Query: 1521 MRGHDSPINAICV--NSTHVFTAADDRTVRIWKAHNLQDGQLSDTGDLGEDIAS 1572
             +GH    + I +  + T ++T   D TVR W   +L++G+     D    I S
Sbjct: 1512 FQGHTDGASCIDISPDGTKLWTGGLDNTVRSW---DLREGRQLQQHDFSSQIFS 1360

 Score = 31.6 bits (70), Expect = 2.7,   Method: Composition-based stats.
 Identities = 15/39 (38%), Positives = 21/39 (53%), Gaps = 2/39 (5%)
 Frame = -3

Query: 1441 HYDGIEALAIQ--GDNLFSGSRDNGIKKWDLAQKGLLQQ 1477
            H DG   + I   G  L++G  DN ++ WDL +   LQQ
Sbjct: 1503 HTDGASCIDISPDGTKLWTGGLDNTVRSWDLREGRQLQQ 1387
>03387
          Length = 1891

 Score = 36.6 bits (83), Expect = 0.087,   Method: Compositional matrix adjust.
 Identities = 33/148 (22%), Positives = 66/148 (44%), Gaps = 9/148 (6%)
 Frame = +1

Query: 1240 HIAEGHTKAVLCVD---STDDLLFTGSKDRTCKVWNLVTGQ-EIMSLGVHPNNVVSVKYC 1295
            H+ + HT  V C+     ++ +L TGS D+T  +W+L   + ++ S   H + +  V++ 
Sbjct: 631  HVVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWS 810

Query: 1296 --NYTSLVFTVSTSYIKVWDIRESAKCIRTLTSSGQVTLGEACSASTSRTVAIPSGES-Q 1352
              N T L  + +   + VWD          L+  G+  L E         + I  G + +
Sbjct: 811  PHNETILASSGTDRRLHVWD----------LSKIGEEQLPEDAEDGPPELLFIHGGHTAK 960

Query: 1353 INQIALNPTGTFLY--AASGNAVRMWDL 1378
            I+  + NP   ++    +  N +++W +
Sbjct: 961  ISDFSWNPNEPWIVCSVSEDNIMQVWQM 1044
>26939
          Length = 388

 Score = 35.4 bits (80), Expect = 0.18,   Method: Composition-based stats.
 Identities = 18/59 (30%), Positives = 30/59 (50%)
 Frame = +2

Query: 1452 GDNLFSGSRDNGIKKWDLAQKGLLQQVPNAHKDWVCALGLVPGHPVLLSGCRGGILKLW 1510
            G  L S S D  I+ WDL  K  ++ +  AH+ +  ++     HP ++SG     +K+W
Sbjct: 2    GKYLVSASDDKTIRVWDLRNKRCMKTL-YAHQHFCTSIDFHKAHPYVISGSVDQTVKVW 175
>01327
          Length = 2215

 Score = 35.0 bits (79), Expect = 0.26,   Method: Compositional matrix adjust.
 Identities = 28/104 (26%), Positives = 46/104 (44%), Gaps = 2/104 (1%)
 Frame = +3

Query: 1449 AIQGDNLFSGSRDNGIKKWDLAQKGLLQQVPNAHKDWVCALGLVPGHPVLLSGCRGGILK 1508
            +IQ     SGS+D  +  +D  Q G L+     H   +  +        + S  R   +K
Sbjct: 66   SIQPGLCLSGSKDKSVVLYDY-QNGRLEDRWTGHDREITKVCYGASCNGMFSASRDKTIK 242

Query: 1509 LWNVDTFVPVGEMRGHDSPINAICVNS--THVFTAADDRTVRIW 1550
            +W       + +  GHD  + AI +N+  T + + + D TVRIW
Sbjct: 243  MWQRGNSHSIRDFIGHDMVVTAIHLNTDNTLLCSGSRDNTVRIW 374

 Score = 34.7 bits (78), Expect = 0.31,   Method: Compositional matrix adjust.
 Identities = 37/143 (25%), Positives = 65/143 (45%), Gaps = 3/143 (2%)
 Frame = +3

Query: 1362 GTFLYAASGNAVRMWDLKRFQSTGKLTGHLGPVMCLTVDQISNGQDLIITGSKDHYIKMF 1421
            G  L  +   +V ++D +  +   + TGH   +  +      NG   + + S+D  IKM+
Sbjct: 78   GLCLSGSKDKSVVLYDYQNGRLEDRWTGHDREITKVCYGASCNG---MFSASRDKTIKMW 248

Query: 1422 DVTEGALGTVSPTHNFEPPHYDGIEALAIQGDN--LFSGSRDNGIKKWDLAQKGLLQQVP 1479
                   G      +F   H   + A+ +  DN  L SGSRDN ++ WD+     L+Q  
Sbjct: 249  Q-----RGNSHSIRDF-IGHDMVVTAIHLNTDNTLLCSGSRDNTVRIWDVETGACLRQ-N 407

Query: 1480 NAHKDWVCALGLVPG-HPVLLSG 1501
            N  ++ V  +  +PG H ++ +G
Sbjct: 408  NIPQNLVTDVKWLPGSHLIIQAG 476

 Score = 30.8 bits (68), Expect = 4.1,   Method: Compositional matrix adjust.
 Identities = 19/82 (23%), Positives = 42/82 (51%), Gaps = 3/82 (3%)
 Frame = +3

Query: 1244 GHTKAV--LCVDSTDDLLFTGSKDRTCKVWNLVTGQEIMSLGVHPNNVVSVKYCNYTSLV 1301
            GH + +  +C  ++ + +F+ S+D+T K+W       I     H   V ++      +L+
Sbjct: 159  GHDREITKVCYGASCNGMFSASRDKTIKMWQRGNSHSIRDFIGHDMVVTAIHLNTDNTLL 338

Query: 1302 FTVS-TSYIKVWDIRESAKCIR 1322
             + S  + +++WD+ E+  C+R
Sbjct: 339  CSGSRDNTVRIWDV-ETGACLR 401

 Score = 30.4 bits (67), Expect = 6.5,   Method: Compositional matrix adjust.
 Identities = 12/40 (30%), Positives = 27/40 (67%), Gaps = 5/40 (12%)
 Frame = +3

Query: 1523 GHDSPINAICVNST--HVFTAADDRTVRIWK---AHNLQD 1557
            GHD  I  +C  ++   +F+A+ D+T+++W+   +H+++D
Sbjct: 159  GHDREITKVCYGASCNGMFSASRDKTIKMWQRGNSHSIRD 278
>14555
          Length = 627

 Score = 34.7 bits (78), Expect = 0.31,   Method: Composition-based stats.
 Identities = 16/45 (35%), Positives = 26/45 (57%), Gaps = 2/45 (4%)
 Frame = -2

Query: 1237 QCVHIAEGHTKAVLCVD--STDDLLFTGSKDRTCKVWNLVTGQEI 1279
            +CV + EGH   + CV    + D   TGS D TC++++L   +E+
Sbjct: 626  ECVQMFEGHEADINCVRFYPSGDAFATGSDDATCRLFDLRADREV 492
>17266
          Length = 480

 Score = 34.3 bits (77), Expect = 0.40,   Method: Composition-based stats.
 Identities = 23/64 (35%), Positives = 31/64 (48%), Gaps = 2/64 (3%)
 Frame = -1

Query: 1489 LGLVPGHPVLLSGCRGGILKLWNVDTFVPVGEMRGHDSPINAIC-VNSTHVF-TAADDRT 1546
            L L P     +SG      KLW+V   +      GH+S INAI    + H F T +DD T
Sbjct: 441  LSLAPDMRTFVSGACDASAKLWDVRDGMCKQTFSGHESDINAITYFPNGHAFATGSDDAT 262

Query: 1547 VRIW 1550
             R++
Sbjct: 261  CRLF 250

 Score = 32.3 bits (72), Expect = 1.6,   Method: Composition-based stats.
 Identities = 32/160 (20%), Positives = 65/160 (40%), Gaps = 2/160 (1%)
 Frame = -1

Query: 1261 TGSKDRTCKVWNLVTGQEIMSLGVHPNNVVSVKYC-NYTSLVFTVSTSYIKVWDIRESAK 1319
            +G+ D + K+W++  G    +   H +++ ++ Y  N  +       +  +++DIR   +
Sbjct: 408  SGACDASAKLWDVRDGMCKQTFSGHESDINAITYFPNGHAFATGSDDATCRLFDIRADQE 229

Query: 1320 CIRTLTSSGQVTLGEACSASTSRTVAIPSGESQINQIALNPTGTFLYAASGN-AVRMWDL 1378
                + S   +  G                   I  +A + +G  L     +    +WD+
Sbjct: 228  I--GMYSHDNIICG-------------------ITSVAFSKSGRLLLGGYDDFNCNIWDV 112

Query: 1379 KRFQSTGKLTGHLGPVMCLTVDQISNGQDLIITGSKDHYI 1418
             + + TG L GH   V CL V +  +    + TGS D ++
Sbjct: 111  LKQERTGVLAGHDNRVSCLGVTEDGSA---VATGSWDSFL 1
>05393
          Length = 904

 Score = 34.3 bits (77), Expect = 0.45,   Method: Composition-based stats.
 Identities = 24/83 (28%), Positives = 35/83 (42%), Gaps = 4/83 (4%)
 Frame = +1

Query: 1258 LLFTGSKDRTCKVWNLVTGQ--EIMSLGVHPNNVVSVKYCNYTSLVFTVSTSY--IKVWD 1313
            L+ T S+D+T KVW++   +   + S  +    +     C     VF V       KVWD
Sbjct: 265  LMITTSEDKTMKVWDIQDDKPTHVFSRNLKMKELHCTGCCPEAPFVFAVGGGRREPKVWD 444

Query: 1314 IRESAKCIRTLTSSGQVTLGEAC 1336
            IRESA       +     L + C
Sbjct: 445  IRESAAVRHQFLNRMPTKLAKEC 513
>31384
          Length = 474

 Score = 33.9 bits (76), Expect = 0.56,   Method: Composition-based stats.
 Identities = 21/53 (39%), Positives = 29/53 (54%), Gaps = 2/53 (3%)
 Frame = -1

Query: 1227 ACKGVRASPLQCVHIAEGHTKAVLCVDSTDD--LLFTGSKDRTCKVWNLVTGQ 1277
            +C  V+ S        + HT  VL VD +DD   +FT S D+T KVW+L + Q
Sbjct: 192  SCWEVQQSGQTIPKAQQTHTGPVLDVDWSDDGTKVFTASCDKTAKVWDLNSNQ 34
>12574
          Length = 521

 Score = 33.1 bits (74), Expect = 1.00,   Method: Composition-based stats.
 Identities = 19/59 (32%), Positives = 32/59 (54%)
 Frame = +3

Query: 1254 STDDLLFTGSKDRTCKVWNLVTGQEIMSLGVHPNNVVSVKYCNYTSLVFTVSTSYIKVW 1312
            S   LL + S D+T K+W   TG+ + +L  H N V    +   ++L+  VS S ++V+
Sbjct: 342  SDSKLLCSASDDKTLKIWEFSTGKCMKTLKGHSNYVFCCNFNPQSNLI--VSGSLMRVF 512
>03156
          Length = 1014

 Score = 32.7 bits (73), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 33/119 (27%), Positives = 55/119 (46%), Gaps = 3/119 (2%)
 Frame = +1

Query: 1386 KLTGHLGPVMCLTVDQISNGQDLIITGSKDHYIKMFDVTEGALGTVSPTHNFEPPHYDGI 1445
            + TGH   +  +      NG   + + S+D  IKM+       G      +F   H   +
Sbjct: 40   RWTGHDREITKVCYGASCNG---MFSASRDKTIKMWQ-----RGNSHSIRDF-IGHDMVV 192

Query: 1446 EALAIQGDN--LFSGSRDNGIKKWDLAQKGLLQQVPNAHKDWVCALGLVPG-HPVLLSG 1501
             A+ +  DN  L SGSRDN ++ WD+     L+Q  N  ++ V  +  +PG H ++ +G
Sbjct: 193  TAIHLNTDNTLLCSGSRDNTVRIWDVETGACLRQ-NNIPQNLVTDVKWLPGSHLIIQAG 366

 Score = 31.2 bits (69), Expect = 3.8,   Method: Compositional matrix adjust.
 Identities = 19/82 (23%), Positives = 42/82 (51%), Gaps = 3/82 (3%)
 Frame = +1

Query: 1244 GHTKAV--LCVDSTDDLLFTGSKDRTCKVWNLVTGQEIMSLGVHPNNVVSVKYCNYTSLV 1301
            GH + +  +C  ++ + +F+ S+D+T K+W       I     H   V ++      +L+
Sbjct: 49   GHDREITKVCYGASCNGMFSASRDKTIKMWQRGNSHSIRDFIGHDMVVTAIHLNTDNTLL 228

Query: 1302 FTVS-TSYIKVWDIRESAKCIR 1322
             + S  + +++WD+ E+  C+R
Sbjct: 229  CSGSRDNTVRIWDV-ETGACLR 291

 Score = 30.4 bits (67), Expect = 5.9,   Method: Compositional matrix adjust.
 Identities = 12/40 (30%), Positives = 27/40 (67%), Gaps = 5/40 (12%)
 Frame = +1

Query: 1523 GHDSPINAICVNST--HVFTAADDRTVRIWK---AHNLQD 1557
            GHD  I  +C  ++   +F+A+ D+T+++W+   +H+++D
Sbjct: 49   GHDREITKVCYGASCNGMFSASRDKTIKMWQRGNSHSIRD 168

 Score = 30.4 bits (67), Expect = 5.9,   Method: Compositional matrix adjust.
 Identities = 17/55 (30%), Positives = 28/55 (50%), Gaps = 2/55 (3%)
 Frame = +1

Query: 1498 LLSGCRGGILKLWNVDTFVPVGEMRGHDSPINAICVNS--THVFTAADDRTVRIW 1550
            + S  R   +K+W       + +  GHD  + AI +N+  T + + + D TVRIW
Sbjct: 100  MFSASRDKTIKMWQRGNSHSIRDFIGHDMVVTAIHLNTDNTLLCSGSRDNTVRIW 264
>35695
          Length = 1651

 Score = 32.3 bits (72), Expect = 1.4,   Method: Compositional matrix adjust.
 Identities = 25/96 (26%), Positives = 44/96 (45%), Gaps = 1/96 (1%)
 Frame = -1

Query: 1375 MWDLKRFQSTGKLTGHLGPVMCLTVDQISNGQDLIITGSKDHYIKMFDVTEGALGTVSPT 1434
            +WD+K+      L  H G ++ LT   ++ G +++I+ S D  I +++  +  L  V P 
Sbjct: 1633 VWDVKQGNMVKTLDAHFGRIIALT--SVTVGCNMVISSSIDKTINVWNF-DKILEEVHPL 1463

Query: 1435 HNFEPPHYDGIEALAIQG-DNLFSGSRDNGIKKWDL 1469
               E P    IE + +    +L   +  N    WDL
Sbjct: 1462 DRMERP----IETVHMAASSSLCVATTRNQTSVWDL 1367
>18320
          Length = 450

 Score = 32.0 bits (71), Expect = 2.1,   Method: Composition-based stats.
 Identities = 21/60 (35%), Positives = 31/60 (51%)
 Frame = -2

Query: 1236 LQCVHIAEGHTKAVLCVDSTDDLLFTGSKDRTCKVWNLVTGQEIMSLGVHPNNVVSVKYC 1295
            L C  I + H+  + C+ S +  L+TGS D   KVW+L  GQ++        NVV+   C
Sbjct: 149  LHC--IDKAHSGWIWCMASLNQHLYTGSWDTKIKVWDL--GQDM--------NVVTSYKC 6
>01598
          Length = 1545

 Score = 31.6 bits (70), Expect = 2.4,   Method: Compositional matrix adjust.
 Identities = 14/28 (50%), Positives = 19/28 (67%)
 Frame = +1

Query: 1253 DSTDDLLFTGSKDRTCKVWNLVTGQEIM 1280
            D+   L+ TGSKDRT +VW L  G++I 
Sbjct: 91   DTGGCLIATGSKDRTIRVWTLSQGKQIF 174
>05303
          Length = 782

 Score = 31.6 bits (70), Expect = 2.6,   Method: Composition-based stats.
 Identities = 18/76 (23%), Positives = 36/76 (47%), Gaps = 15/76 (19%)
 Frame = -3

Query: 1458 GSRDNGIKKWDLAQKGLLQQVPNAH-----------KDWVCALGLVPGHPVLLSGCRGGI 1506
            G +DN +  W++ +K  L  V +AH           ++W+ A+  +    ++ +G + G 
Sbjct: 648  GGQDNSVSLWNVNKKKALVCVTSAHSGCSQIEGSKGENWITAVASLQFTDLVATGSKDGC 469

Query: 1507 LKLW----NVDTFVPV 1518
            ++LW    N    VP+
Sbjct: 468  IRLWQCSANFHHLVPL 421
>06576
          Length = 1547

 Score = 31.2 bits (69), Expect = 3.2,   Method: Composition-based stats.
 Identities = 13/46 (28%), Positives = 25/46 (54%), Gaps = 3/46 (6%)
 Frame = -2

Query: 1521 MRGHDSPINAICVNST---HVFTAADDRTVRIWKAHNLQDGQLSDT 1563
            ++GH   +N++  + T    V +  DD T R+W   + QDG+  ++
Sbjct: 1096 VKGHTDFVNSVTFSPTEEDQVXSTGDDLTCRVWTGKDGQDGRYGES 959
>23766
          Length = 1463

 Score = 30.4 bits (67), Expect = 5.4,   Method: Composition-based stats.
 Identities = 19/51 (37%), Positives = 28/51 (54%), Gaps = 1/51 (1%)
 Frame = -3

Query: 296 SINCGL-LALGNVISALGDKSKRATHVPYRDSKLTRLLQDSLGGNSQTIMI 345
           S  C L LA+ NV+  LG       H P+ +S+ T L  DSL  +S+ I++
Sbjct: 810 SFRCSLILAIKNVLLCLGKILVSYFHTPFSESQ*TSLRTDSLDVSSRQIIL 658
>16199
          Length = 694

 Score = 30.4 bits (67), Expect = 6.1,   Method: Composition-based stats.
 Identities = 19/81 (23%), Positives = 33/81 (40%), Gaps = 1/81 (1%)
 Frame = +2

Query: 1322 RTLTSSGQVTLGEACSASTSRTVAIPSGESQINQIALNPTG-TFLYAASGNAVRMWDLKR 1380
            R+ TS+  V   + C  S     A+   +        +P G  F      + +++WDLK 
Sbjct: 8    RSQTSAQDVC*PKVCDKSGPSVPALTCAQ-------FHPDGLIFATGTEDSVIKIWDLKE 166

Query: 1381 FQSTGKLTGHLGPVMCLTVDQ 1401
              +     GH GPV  ++  +
Sbjct: 167  RANVANFQGHQGPVTSISFSE 229
>01258
          Length = 1027

 Score = 29.6 bits (65), Expect = 9.0,   Method: Composition-based stats.
 Identities = 11/34 (32%), Positives = 22/34 (64%)
 Frame = +1

Query: 1279 IMSLGVHPNNVVSVKYCNYTSLVFTVSTSYIKVW 1312
            +++L  H NN++S+ + NYT++     TS + +W
Sbjct: 748  VLNLKRHKNNIISIYFVNYTNV-----TSLLSIW 834
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|22165382|ref|NP_666199.1| casein kinase 1, alpha 1
[Mus musculus]
         (325 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

18481                                                                 181   3e-46
16959                                                                 140   5e-34
32357                                                                 130   1e-30
00300                                                                  64   7e-11
13592                                                                  63   2e-10
06405                                                                  54   7e-08
00715                                                                  52   2e-07
03508                                                                  51   5e-07
01718                                                                  50   1e-06
03240                                                                  50   1e-06
01707                                                                  49   4e-06
18921                                                                  48   5e-06
21079                                                                  48   6e-06
01756                                                                  47   8e-06
14126                                                                  46   2e-05
01106                                                                  45   3e-05
15910                                                                  45   5e-05
11404                                                                  44   9e-05
12786                                                                  44   1e-04
29581                                                                  43   2e-04
26711                                                                  43   2e-04
01060                                                                  43   2e-04
31885                                                                  41   7e-04
16708                                                                  41   8e-04
01966                                                                  41   8e-04
04591                                                                  41   8e-04
12721                                                                  40   9e-04
11780                                                                  40   0.001
14477                                                                  40   0.001
26009                                                                  39   0.003
12704                                                                  39   0.003
14420                                                                  38   0.005
27405                                                                  38   0.005
21433                                                                  38   0.006
30755                                                                  37   0.012
21808                                                                  37   0.013
28638                                                                  37   0.015
19094                                                                  35   0.034
26560                                                                  35   0.035
36481                                                                  35   0.039
01392                                                                  35   0.043
31489                                                                  35   0.051
00638                                                                  35   0.052
13212                                                                  34   0.082
17975                                                                  34   0.097
28157                                                                  34   0.10 
27546                                                                  33   0.16 
13066                                                                  33   0.20 
04138                                                                  33   0.20 
21800                                                                  32   0.31 
19301                                                                  30   0.89 
37602                                                                  29   2.3  
29360                                                                  29   2.3  
07940                                                                  29   2.6  
19761                                                                  29   2.8  
14116                                                                  28   6.4  
20559                                                                  28   6.6  
20640                                                                  28   6.7  
12672                                                                  28   7.2  
32359                                                                  27   8.0  
>18481
          Length = 437

 Score =  181 bits (460), Expect = 3e-46,   Method: Compositional matrix adjust.
 Identities = 79/145 (54%), Positives = 114/145 (78%)
 Frame = -1

Query: 31  IYLAINITNGEEVAVKLESQKARHPQLLYESKLYKILQGGVGIPHIRWYGQEKDYNVLVM 90
           IY   N  +G+++AVK+E+   +H  L YE+K+Y+ +    G+P +  YG EK +N LVM
Sbjct: 437 IYQGYNTQDGKDIAVKIEAIDVKHQLLHYEAKVYEQIGRHPGLPTMYHYGTEKHFNALVM 258

Query: 91  DLLGPSLEDLFNFCSRRFTMKTVLMLADQMISRIEYVHTKNFIHRDIKPDNFLMGIGRHC 150
           +LLGPSLE+LF  C RRFT+KT+LM++DQ++SR+E++H K FIHRD+KPDNFLMG+GRHC
Sbjct: 257 ELLGPSLEELFVICKRRFTLKTILMVSDQLLSRLEFIHQKCFIHRDLKPDNFLMGLGRHC 78

Query: 151 NKLFLIDFGLAKKYRDNRTRQHIPY 175
           ++L++IDFGL+K+Y+D +   HIPY
Sbjct: 77  HRLYIIDFGLSKRYKDTQGTMHIPY 3
>16959
          Length = 1747

 Score =  140 bits (354), Expect = 5e-34,   Method: Compositional matrix adjust.
 Identities = 62/97 (63%), Positives = 74/97 (76%)
 Frame = -1

Query: 205  ESLGYVLMYFNRTSLPWQGLKAATXXXXXXXXXXXXMSTPVEVLCKGFPAEFAMYLNYCR 264
            E+LGYVLMYFNR SLPWQGLKAAT            ++TPV+ LCK FP+EF+++LNY R
Sbjct: 1747 EALGYVLMYFNRGSLPWQGLKAATKKQKCERISEKKIATPVDSLCKSFPSEFSIFLNYSR 1568

Query: 265  GLRFEEAPDYMYLRQLFRILFRTLNHQYDYTFDWTML 301
             LRF+E PDY YLRQLFR+LFRT NH +DY FDW +L
Sbjct: 1567 DLRFDEGPDYTYLRQLFRVLFRTYNHHFDYAFDWNIL 1457
>32357
          Length = 625

 Score =  130 bits (326), Expect = 1e-30,   Method: Compositional matrix adjust.
 Identities = 73/159 (45%), Positives = 98/159 (61%), Gaps = 5/159 (3%)
 Frame = -2

Query: 9   AEFIVGGKYKLVRKIGSGSFGDIYLAINITNGEEVAVKLESQKARHPQLLYESKLYKILQ 68
            + +V GKY+L++KIGSGSFG+IYL ++ T+GEEVAVKLE + A+HPQL YESKLY++LQ
Sbjct: 456 TDLLVNGKYRLMKKIGSGSFGEIYLGVHNTSGEEVAVKLELKNAKHPQLYYESKLYRVLQ 277

Query: 69  GGVGIPHIRWYGQEKDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMISRIEYVH 128
           GGVGIP+ RW+GQE       M       + ++  CS      +    A    +R     
Sbjct: 276 GGVGIPYCRWFGQEST----TM*W*WIYWDPVWKTCSTTVGANSP*NSAH---ARRPDDQ 118

Query: 129 TKNFIHRDI-----KPDNFLMGIGRHCNKLFLIDFGLAK 162
               IH  +     +    LMGIGRH NK+F+ID+GLAK
Sbjct: 117 QAGIIHNKLHSSGPQARQLLMGIGRHANKVFIIDYGLAK 1
>00300
          Length = 2318

 Score = 64.3 bits (155), Expect = 7e-11,   Method: Compositional matrix adjust.
 Identities = 63/215 (29%), Positives = 99/215 (46%), Gaps = 12/215 (5%)
 Frame = -1

Query: 22   KIGSGSFGDIYLAINITNGEEVAVK-LESQKARHPQLLYESKLYKILQGGVGIPHIRWYG 80
            KIG G FG +Y A+N++ GE +A+K ++ Q     QL       KI +G      +++YG
Sbjct: 1637 KIGEGQFGKVYTAVNMSTGELMALKEMKFQPNDLQQLREMCDEIKIFEGIQHENLVKYYG 1458

Query: 81   QE--KDYNVLVMDLLGP-SLED-----LFNFCSRRFTMKTVLMLADQMISRIEYVHTKNF 132
             E  KD  ++ M+     ++E+     L  +  RR+T + VL         + ++H  + 
Sbjct: 1457 VEVHKDEMLMFMEYCDTGTIEEAAKMGLPEYLIRRYTREIVLA--------VNHLHENSI 1302

Query: 133  IHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKNLTGTARYASINA 192
            +HRDIK  N  +    H     L DFG + K + + T   +P  E  NL GT  Y +   
Sbjct: 1301 VHRDIKGANIFLTSNGHVK---LGDFGCSVKLKSHTT---MP-GEFHNLVGTTAYMAPEV 1143

Query: 193  HLGIEQ---SRRDDMESLGYVLMYFNRTSLPWQGL 224
                +Q    R  D+ SLG V++       PW  L
Sbjct: 1142 FTQNDQGGYGRAADIWSLGCVVIEMATGKRPWHDL 1038
>13592
          Length = 980

 Score = 62.8 bits (151), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 66/217 (30%), Positives = 97/217 (44%), Gaps = 17/217 (7%)
 Frame = +2

Query: 22  KIGSGSFGDIYLAINITNGEEVAVK-LESQKARHPQLLYESKLYKILQGGVGIPH---IR 77
           KIG G FG +Y A+N   GE +A+K +  Q      L   ++  KIL+   GI H   +R
Sbjct: 5   KIGQGRFGKVYTAVNNNTGELMAMKEIAIQPGETRALKNVAEELKILE---GIKHKNLVR 175

Query: 78  WYGQE--KDYNVLVMDLLGP-SLEDLFNFC-------SRRFTMKTVLMLADQMISRIEYV 127
           +YG E  ++  ++ M+L    +LE L           SRRFT         Q++S +  +
Sbjct: 176 YYGIEVHREELLIFMELCSEGTLESLVELTGGLPEALSRRFTA--------QLLSGVAEL 331

Query: 128 HTKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKNLTGTARY 187
           H    +HRDIK  N  +  G   N L L DFG A K + + T   +P  E +   GT  Y
Sbjct: 332 HKHGIVHRDIKTANIFLVDGS--NSLKLGDFGSAVKIQAHTT---VP-GELQGYVGTQAY 493

Query: 188 ASINAHLGIE---QSRRDDMESLGYVLMYFNRTSLPW 221
            +             R  D+ S+G V++       PW
Sbjct: 494 MAPEVFTKTNSDGHGRLADIWSVGCVVVEMASGKRPW 604
>06405
          Length = 1965

 Score = 54.3 bits (129), Expect = 7e-08,   Method: Compositional matrix adjust.
 Identities = 44/154 (28%), Positives = 75/154 (48%), Gaps = 2/154 (1%)
 Frame = +1

Query: 22  KIGSGSFGDIYLAINITNGEEVAVK-LESQKARHPQLLYESKLYKILQGGVGIPHIRWYG 80
           ++G G +GD+Y A+     + VAVK L+         L E+ + K ++    +  +    
Sbjct: 280 RLGGGQYGDVYEAMWKRYNKIVAVKTLKEDTMALNDFLEEAAIMKEMKHPNLVQLLGVCT 459

Query: 81  QEKDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLM-LADQMISRIEYVHTKNFIHRDIKP 139
           +E  + ++   +   +L D     +R     T LM +A Q+ S + Y+ TKNFIHRD+  
Sbjct: 460 REPPFYIVTEFMPHGNLLDYLRSSTREENGPTALMYMATQIASGMAYLETKNFIHRDLAA 639

Query: 140 DNFLMGIGRHCNKLFLIDFGLAKKYRDNRTRQHI 173
            N L+      N + + DFGLA+  +D+    HI
Sbjct: 640 RNCLVA---DSNMVKVADFGLARLMKDDTYTAHI 732
>00715
          Length = 1788

 Score = 52.4 bits (124), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 54/210 (25%), Positives = 89/210 (42%), Gaps = 26/210 (12%)
 Frame = +1

Query: 43  VAVKLESQKARHPQLLYESKLYKILQGGVGIPHIRWYG--------QEKDYNVLVMDLLG 94
           VAVK+  +++ +P+ L +S   ++L    G+ H+            + +D   L M+ +G
Sbjct: 7   VAVKIYHKRSSNPRALRQSYSNELLAFRCGLRHVNVVSILGATSLHRFEDGAWLAMEYVG 186

Query: 95  P-SLEDLFNFCSRRFTMKTVLMLADQMISRIEYVHTKNFIHRDIKPDNFLMGIGRHCNKL 153
           P +L+ + N   +       L LA QM   + Y+H+ N +H D+KP N L+       KL
Sbjct: 187 PLNLQTILNDHQQDIDSSMRLSLALQMARGLHYLHSINIVHLDLKPANCLLTRDL---KL 357

Query: 154 FLIDFGLAKKYRDNRTRQHIPYRE-----------------DKNLTGTARYASINAHLGI 196
            + DFG   +     T   +  RE                    L GT  Y +     G+
Sbjct: 358 RIADFGCCHQL--TPTGLDMGEREGGMAGNELELTPVQGAWKNELAGTLAYRAPELLKGL 531

Query: 197 EQSRRDDMESLGYVLMYFNRTSLPWQGLKA 226
           + S R D+ SLG  L        P++G+ A
Sbjct: 532 QPSVRSDVYSLGITLWQMCTRQGPYEGVPA 621
>03508
          Length = 1463

 Score = 51.2 bits (121), Expect = 5e-07,   Method: Compositional matrix adjust.
 Identities = 41/149 (27%), Positives = 73/149 (48%), Gaps = 1/149 (0%)
 Frame = +1

Query: 17  YKLVRKIGSGSFGDIYLAINITNGEEVAVKLESQKARHPQLLYESKLYKILQGGVGIPHI 76
           Y++VRK+G G + +++ AIN+TN E+  +K+     +         L + L+GG  +  I
Sbjct: 595 YQIVRKLGRGKYSEVFEAINVTNNEKCVIKILKPVKKKKIKREIKIL-ENLRGGTNV--I 765

Query: 77  RWYGQEKDYNVLVMDLLGPSLEDL-FNFCSRRFTMKTVLMLADQMISRIEYVHTKNFIHR 135
                 KD       L+   + +  F    + FT   +     +++  +++ H+   +HR
Sbjct: 766 TLLAIVKDPVSRTPALIFEHVNNTDFKQLYQTFTDYDIRFYLYELMKALDFCHSMGIMHR 945

Query: 136 DIKPDNFLMGIGRHCNKLFLIDFGLAKKY 164
           D+KP N +  I     KL LID+GLA+ Y
Sbjct: 946 DVKPHNVM--IDHENKKLRLIDWGLAEFY 1026
>01718
          Length = 959

 Score = 50.4 bits (119), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 43/194 (22%), Positives = 82/194 (42%), Gaps = 1/194 (0%)
 Frame = +3

Query: 19  LVRKIGSGSFGDIYLAINITNGEEVAVKLESQKARHPQLLYESKLYKILQGGVGIPHIRW 78
           +  KIG+G F +++   +   G+ +A+K+ +  +    +L E +L   LQ    +  +  
Sbjct: 159 ICEKIGAGFFSEVFKVTHRITGQVMALKMNTMTSNRHNMLREVQLLNRLQHANILRFMGV 338

Query: 79  YGQEKDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMISRIEYVHTKNFIHRDIK 138
              E   + L   +   +LE L             + L   +   ++Y+H+  FIHRD+ 
Sbjct: 339 CVHEGQLHALTEYIPSGNLEQLLEKKDEELPWTQRIQLTLGLARGLDYLHSTRFIHRDLT 518

Query: 139 PDNFLM-GIGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKNLTGTARYASINAHLGIE 197
             N L+     H     + DFGLA K  D   ++ +P        G+  + +     G  
Sbjct: 519 SKNILIRREDNHGYHAVIADFGLATKIPDPLDKEKLPT------VGSPYWMAPEVLNGHF 680

Query: 198 QSRRDDMESLGYVL 211
            + R D+ S+G ++
Sbjct: 681 YNERADLFSVGIIM 722
>03240
          Length = 1683

 Score = 49.7 bits (117), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 45/155 (29%), Positives = 70/155 (45%), Gaps = 6/155 (3%)
 Frame = -3

Query: 17   YKLVRKIGSGSFGDIYLAINITNGEEVAVKL--ESQKARHPQLLYESKLYKILQGGVGIP 74
            ++ ++ +G G+FG++ L      G   A+K   +S   +  Q+ +      IL       
Sbjct: 1285 FEKIKTLGVGAFGEVSLCRKNDTGMLYAMKTLRKSDVLKRNQVAHVKAERDILAEADNEW 1106

Query: 75   HIRWYGQEKDYNVL--VMDLLGPSLEDLFNFCSRRFTMKTVLM--LADQMISRIEYVHTK 130
             ++ Y   +D+N L  VMD +     DL     R   +   L      +++  IE VH  
Sbjct: 1105 VVKLYYSFQDHNYLYFVMDYVPGG--DLMGLLIRMEILDEPLARFYVAELVQAIESVHRM 932

Query: 131  NFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYR 165
             FIHRDIKPDN L+    H   + L DFGL   +R
Sbjct: 931  GFIHRDIKPDNILIDRNGH---IKLTDFGLCTGFR 836
>01707
          Length = 757

 Score = 48.5 bits (114), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 42/151 (27%), Positives = 73/151 (48%), Gaps = 4/151 (2%)
 Frame = +1

Query: 16  KYKLVRKIGSGSFGDIYLAINITNGEEVAVKLESQKARHPQL----LYESKLYKILQGGV 71
           KY+ + KIG GS+G ++   N    + VA+K   +    P +    + E ++ K L+   
Sbjct: 67  KYEKIGKIGEGSYGVVFKCRNKETSQLVAIKKFVESEDDPLIKKIAMREIRMLKQLKHPN 246

Query: 72  GIPHIRWYGQEKDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMISRIEYVHTKN 131
            +  I  + ++K  + LV D +  +L +  +   R      V  +  Q +  + + H  N
Sbjct: 247 LVRLIEVFRRKKRLH-LVFDYVDHTLLNELDRYPRGLPEPMVKRIIYQTLLAVNFCHQYN 423

Query: 132 FIHRDIKPDNFLMGIGRHCNKLFLIDFGLAK 162
            IHRD+KP+N L  I R   ++ L DFG A+
Sbjct: 424 TIHRDVKPENIL--ITRQ-GQVKLCDFGFAR 507
>18921
          Length = 697

 Score = 47.8 bits (112), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 36/159 (22%), Positives = 79/159 (49%), Gaps = 3/159 (1%)
 Frame = +2

Query: 17  YKLVRKIGSGSFGDIYLAINITNGEEVAVKLESQKARHPQLLYESKLYKILQGGVGIPHI 76
           + ++ K+G GS+G ++ +++   G+ +A+K         +++ E     I+Q       +
Sbjct: 35  FDILGKLGEGSYGSVFKSLHKETGQVLAIKQVPVDTDLQEIIKE---ISIMQQCDSKYIV 205

Query: 77  RWYGQE-KDYNV-LVMDLLGP-SLEDLFNFCSRRFTMKTVLMLADQMISRIEYVHTKNFI 133
           ++YG   K+ ++ +VM+  G  S+ D+    ++    + +  +    +  + Y+H++  I
Sbjct: 206 KYYGSYFKNTDLWIVMEYCGAGSVSDIMRLRNKTLVEREIATILYYTLKGLXYLHSRRKI 385

Query: 134 HRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDNRTRQH 172
           HRDIK  N L+    H     L DFG+A +  D   +++
Sbjct: 386 HRDIKAGNILLNNEGHAK---LADFGVAGQLTDTMAKRN 493
>21079
          Length = 878

 Score = 47.8 bits (112), Expect = 6e-06,   Method: Compositional matrix adjust.
 Identities = 37/127 (29%), Positives = 63/127 (49%), Gaps = 3/127 (2%)
 Frame = +1

Query: 87  VLVMDLLGPSLEDLFNFCSRR---FTMKTVLMLADQMISRIEYVHTKNFIHRDIKPDNFL 143
           VLVM+ +G    +LF    R     T +  +    Q+ S + Y+HT++ +H D+KP+N L
Sbjct: 52  VLVMEFVGAG--ELFERVIRDDFVLTERDCVHFVRQICSGVGYMHTQSILHLDLKPENVL 225

Query: 144 MGIGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKNLTGTARYASINAHLGIEQSRRDD 203
             +  + N++ +IDFGLA+ Y+   + Q         L GT  + +       E +   D
Sbjct: 226 C-VSDNSNQIKIIDFGLARFYKPGDSLQ--------VLFGTPEFIAPEVVNYDEINFTTD 378

Query: 204 MESLGYV 210
           M S+G +
Sbjct: 379 MWSIGVI 399
>01756
          Length = 1858

 Score = 47.4 bits (111), Expect = 8e-06,   Method: Compositional matrix adjust.
 Identities = 43/164 (26%), Positives = 75/164 (45%), Gaps = 11/164 (6%)
 Frame = -3

Query: 15   GKYKLVRKIGSGSFGDIYLAINITNGEEVAVK---LESQKARHP-QLLYESKLYKILQGG 70
             KY+ + KIG G+FG+++ A      + VA+K   ++++K   P   L E K+ ++L   
Sbjct: 1742 AKYEKLAKIGQGTFGEVFKARCKKTKQVVAMKKVLMDNEKEGFPITALREIKILQLLNHE 1563

Query: 71   VGIPHIRWYGQE-------KDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMISR 123
              +  I     +       K    LV +     L  L +  S  F +  +  +  Q+++ 
Sbjct: 1562 NVVDLIEICSTKATSANRYKSMFYLVFEFCEHDLAGLLSNMSVVFNLPEIKEVMKQLMNG 1383

Query: 124  IEYVHTKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDN 167
            + Y+H    +HRD+K  N L+        L L DFGLA+ +  N
Sbjct: 1382 LYYIHRNKILHRDMKAANILIT---KQGVLKLADFGLARAFSVN 1260
>14126
          Length = 1265

 Score = 45.8 bits (107), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 46/163 (28%), Positives = 79/163 (48%), Gaps = 14/163 (8%)
 Frame = +3

Query: 16  KYKLVRKIGSGSFGDIYLAINITN-GEEVAVK---LESQKARHPQL-LYESKLYKILQG- 69
           KY+ V  IG+G++G +Y A ++ N GE VA+K   L + +   P + + E  + K L+  
Sbjct: 192 KYEEVAVIGNGAYGTVYKARDLRNQGEFVAMKRIRLNNTEEGMPMMAIREISMLKQLEQY 371

Query: 70  -------GVGIPHIRWYGQEKDYNVLVMDLLGPSLEDLFNFC-SRRFTMKTVLMLADQMI 121
                   + + H     +E   N LV + +   L      C S       +  L  Q++
Sbjct: 372 EHPNVVRLLDVSHNTITDREIRLN-LVFEYIEHDLATYLAKCPSPGLGPDRIKDLMLQLL 548

Query: 122 SRIEYVHTKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKY 164
           + ++++H+   +HRD+KP N L+       +L L DFGLA+ Y
Sbjct: 549 NGVDFLHSNRIVHRDLKPQNLLIS---KDGRLKLADFGLARIY 668
>01106
          Length = 878

 Score = 45.4 bits (106), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 41/149 (27%), Positives = 73/149 (48%), Gaps = 17/149 (11%)
 Frame = +3

Query: 15  GKYKLVRKIGSGSFGDIYLAINITNGEEVAVKLESQKARH--PQLLYESKLYKIL-QGGV 71
           G+Y ++RK+G G F  ++L  ++T    VA+K+  + A+H     L E KL K + +  V
Sbjct: 318 GRYHVIRKLGWGHFSTVWLCWDLTCKRFVALKV-VKSAQHYTETALDEVKLLKCVRESDV 494

Query: 72  GIP----------HIRWYGQEKDYNVLVMDLLGPSLEDLF---NFCSRRFTMKTVLMLAD 118
             P            +  G    +  +V ++LG +L  L    N+  +   +  V ++  
Sbjct: 495 ADPARAKCVQLLDDFKISGVNGTHVAMVFEVLGYNLLKLIIRSNY--QGIPIHNVKLIIR 668

Query: 119 QMISRIEYVHTK-NFIHRDIKPDNFLMGI 146
           Q++  + Y+H K   IH DIKP+N L+ +
Sbjct: 669 QVLEGLSYMHAKCRIIHTDIKPENILICV 755
>15910
          Length = 1361

 Score = 44.7 bits (104), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 27/104 (25%), Positives = 47/104 (45%)
 Frame = +2

Query: 107 RFTMKTVLMLADQMISRIEYVHTKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRD 166
           ++T K        ++  ++Y+H    +HRD+KP+N L       +KL L DFGL++    
Sbjct: 452 QYTEKDAARAISDILHGVQYIHANGVVHRDLKPENLLYECMTDDSKLKLADFGLSRIIE- 628

Query: 167 NRTRQHIPYREDKNLTGTARYASINAHLGIEQSRRDDMESLGYV 210
                  P  +   + GT  Y +     G + +   DM S+G +
Sbjct: 629 -------PEVQMSTVCGTPGYCAPEVLKGDKYTPSVDMWSVGVI 739
>11404
          Length = 563

 Score = 43.9 bits (102), Expect = 9e-05,   Method: Compositional matrix adjust.
 Identities = 38/140 (27%), Positives = 71/140 (50%), Gaps = 9/140 (6%)
 Frame = +1

Query: 14  GGKYKLVRKIGSGSFGDIYLAINITNGEEVAVKL-ESQKARHPQLLYESKLYKILQ---- 68
             +Y++   IG GSFG +  A + T+ E+VA+K+ +++K    Q   E KL +++     
Sbjct: 136 ADRYEIDSLIGKGSFGQVVKAYDHTDNEQVAIKIIKNKKPFLNQAQIEVKLLEMMNRHDT 315

Query: 69  -GGVGIPHIRWYGQEKDYNVLVMDLLGPSLEDLF-NFCSRRFTMKTVLMLADQMISRIEY 126
                I  ++ +   + +  LV +LL  +L DL  N   R  ++      A Q+ + + +
Sbjct: 316 DNKYYIVRLKRHFMFRSHLCLVFELLSYNLYDLLRNTNFRGVSLNLTRKFAQQLCTALLF 495

Query: 127 VHTK--NFIHRDIKPDNFLM 144
           + T   + IH D+KP+N L+
Sbjct: 496 LATPEMSIIHCDLKPENILL 555
>12786
          Length = 460

 Score = 43.5 bits (101), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 29/92 (31%), Positives = 45/92 (48%), Gaps = 1/92 (1%)
 Frame = -3

Query: 119 QMISRIEYVHTKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDNRTRQHIPYRED 178
           +M+  ++ +H +  IH D+KP NF++  G     L LIDFG+A   + ++T      R  
Sbjct: 386 EMLRAVKALHNEGVIHSDLKPANFMLVAG----NLKLIDFGIANTLQQDKTSVLKDSR-- 225

Query: 179 KNLTGTARYASINAHL-GIEQSRRDDMESLGY 209
               GT  Y S  A +   + S  D ME  G+
Sbjct: 224 ---VGTPSYMSPEAIMAACDDSADDSMEEDGH 138
>29581
          Length = 1278

 Score = 42.7 bits (99), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 28/85 (32%), Positives = 41/85 (48%)
 Frame = -2

Query: 80   GQEKDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMISRIEYVHTKNFIHRDIKP 139
            G+  D   LVM+     L  L +     F+   V  +  Q++  + Y+H    IHRD+K 
Sbjct: 1142 GKSLDSLFLVMEYCEQDLASLLDNMPAPFSESQVKCIVLQLLKGLRYLHEAFIIHRDLKV 963

Query: 140  DNFLMGIGRHCNKLFLIDFGLAKKY 164
             N LM   + C K  + DFGLA+ Y
Sbjct: 962  SNLLM-TDKGCVK--IADFGLARNY 897
>26711
          Length = 405

 Score = 42.7 bits (99), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 18/45 (40%), Positives = 30/45 (66%)
 Frame = -2

Query: 119 QMISRIEYVHTKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKK 163
           Q++  +++VH +  +H D+KP N L+  G   + + LIDFGLA+K
Sbjct: 392 QVLDILQHVHAQGVVHMDLKPSNLLLS-GDKLDSVQLIDFGLARK 261
>01060
          Length = 1800

 Score = 42.7 bits (99), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 47/190 (24%), Positives = 81/190 (42%), Gaps = 21/190 (11%)
 Frame = +1

Query: 21  RKIGSGSFGDIYLAINITNGEEVAVK----------LESQKARHPQLLYESKLYKILQGG 70
           +KIG G++G +Y   +   G ++A+K          + S   R   +L E +   I+   
Sbjct: 91  QKIGEGTYGVVYKCRHRATGRKLAMKKIRLRGSEDGVPSSAIREIAMLRELRHTNIVCLE 270

Query: 71  VGIPHIRWYGQEKDYNVLVMDLLGPSLE---DLFN---FCSRRFTMKTVLMLADQMISRI 124
             I        E +   LV + L   L+   D F       RR     V     Q+++ I
Sbjct: 271 DVI-------MEDERLFLVFEFLSMDLKMYIDKFPEGVVLDRRLVKSYVF----QIVTGI 417

Query: 125 EYVHTKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYR-DNRTRQH----IPYREDK 179
            + H +  +HRD+KP N L+    H   + + DFG+A+ +    R   H    + YR  +
Sbjct: 418 XFCHQRRIVHRDLKPQNLLIN---HTGAIKIADFGMARTFALPVRAYTHEVVTLWYRAPE 588

Query: 180 NLTGTARYAS 189
            L G ++Y++
Sbjct: 589 ILMGASKYST 618
>31885
          Length = 529

 Score = 41.2 bits (95), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 17/50 (34%), Positives = 30/50 (60%)
 Frame = -2

Query: 119 QMISRIEYVHTKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDNR 168
           Q+   ++Y+ ++  +HRDIKPDN L+    HC+   + DF +A +  D+ 
Sbjct: 348 QLALVLDYLRSQKIVHRDIKPDNILLDEQGHCH---VTDFNIATQLEDDE 208
>16708
          Length = 1397

 Score = 40.8 bits (94), Expect = 8e-04,   Method: Compositional matrix adjust.
 Identities = 39/165 (23%), Positives = 70/165 (42%), Gaps = 18/165 (10%)
 Frame = -1

Query: 19   LVRKIGSGSFGDIYLAINITNGEEVAVKLESQKARHPQLLYESKLYKILQGGVGIPHIRW 78
            +++ +G G FG +Y A  ++  E+ A+K  S    H   L E +    ++GG  +  +  
Sbjct: 1391 ILQVLGKGVFGKVYEARLLSTHEKAALK-TSILCHHS--LDEVEALGRIEGGFYLAQM-- 1227

Query: 79   YGQEKDYNVLVMDLLGPSLEDLFNF------CS------------RRFTMKTVLMLADQM 120
                  +   V  L  P +  L +F      C+            R      V  +A Q 
Sbjct: 1226 ------FGAWVTCLPFPKMNILLHFYEMGPLCNVYAHYKNKEMPIRWSNPAMVCCIAGQX 1065

Query: 121  ISRIEYVHTKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYR 165
            +  +E++H    +H D+K DN L+    +C    L D+G+A+ Y+
Sbjct: 1064 VCALEHIHELGVVHMDVKADNVLVDAHGNCK---LTDYGIAQLYK 939
>01966
          Length = 1735

 Score = 40.8 bits (94), Expect = 8e-04,   Method: Compositional matrix adjust.
 Identities = 15/46 (32%), Positives = 28/46 (60%)
 Frame = -1

Query: 119  QMISRIEYVHTKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKY 164
            Q+++ I + H +  +HRD+KP N L+    H   + + DFG+A+ +
Sbjct: 1384 QIVTGINFCHQRRIVHRDLKPQNLLIN---HTGAIKIADFGMARTF 1256
>04591
          Length = 1117

 Score = 40.8 bits (94), Expect = 8e-04,   Method: Compositional matrix adjust.
 Identities = 24/71 (33%), Positives = 38/71 (53%), Gaps = 3/71 (4%)
 Frame = -2

Query: 97  LEDLFNFCSRRFTMKTVLMLADQMISRIEYVHTKNFIHRDIKPDNFLM---GIGRHCNKL 153
           L  L N    +F++     L  Q+++ + Y+HTK  +HRDIK  N L+   G+      L
Sbjct: 939 LAGLLNNLRVKFSLADKKNLMSQLLNGLFYIHTKQILHRDIKAANILLTRDGV------L 778

Query: 154 FLIDFGLAKKY 164
            L DFGL++ +
Sbjct: 777 KLADFGLSRPW 745
>12721
          Length = 821

 Score = 40.4 bits (93), Expect = 9e-04,   Method: Compositional matrix adjust.
 Identities = 47/202 (23%), Positives = 88/202 (43%), Gaps = 2/202 (0%)
 Frame = +1

Query: 22  KIGSGSFGDIYLAINITNGEEVAVK-LESQKARHPQLLYESKLYKILQGGVGIPHIRWYG 80
           KIG GS G + +A +  +G ++AVK ++ +K +  +LL+   +         I  +    
Sbjct: 109 KIGEGSTGIVCIATS-RDGRQMAVKKMDLRKQQRRELLFNEVVVMRDYHHPNIVEMYNSY 285

Query: 81  QEKDYNVLVMDLL-GPSLEDLFNFCSRRFTMKTVLMLADQMISRIEYVHTKNFIHRDIKP 139
              D   +VM+ + G +L D+    + R     +  +    +  + ++H    IHRDIK 
Sbjct: 286 LVNDELWVVMEFMEGGALTDIVT--NNRMDEVQIATVCRACLKALAFLHANGVIHRDIKS 459

Query: 140 DNFLMGIGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKNLTGTARYASINAHLGIEQS 199
           D+ L+    H  K+ L DFG   +   +  ++       K+L GT  + +      +   
Sbjct: 460 DSILLS---HDGKVKLXDFGFCAQVTQDLQKR-------KSLVGTPYWMAPEVISRLPYG 609

Query: 200 RRDDMESLGYVLMYFNRTSLPW 221
              D+ SLG ++M       P+
Sbjct: 610 PEVDIWSLGIMVMEMIDAEPPF 675
>11780
          Length = 1713

 Score = 40.4 bits (93), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 42/145 (28%), Positives = 64/145 (44%), Gaps = 5/145 (3%)
 Frame = +3

Query: 23  IGSGSFGDIYLAINITNGEEVAVKLESQKARHPQ-LLYESKLYKILQGGVGIPHIRWYGQ 81
           IG G FGD+Y  +    G+ VA+K    K R  Q  L E+ +   L+    +  I     
Sbjct: 621 IGKGDFGDVYKGM--YRGQPVAIKQLKDKDRGEQSFLQEASVMTSLRHDNLVRLIGVVLG 794

Query: 82  EKDYNVLVMDLLGPSLEDLFNFCSRR----FTMKTVLMLADQMISRIEYVHTKNFIHRDI 137
           E  +  LV + +G    +L  +   R     T K  +  A    + +EY+ +K  +HRD+
Sbjct: 795 ETIF--LVTEFMGKG--NLVEYLRSRGRSVITKKDQINFATDTCAAMEYLESKRLVHRDL 962

Query: 138 KPDNFLMGIGRHCNKLFLIDFGLAK 162
              N L+       K  + DFGLAK
Sbjct: 963 AARNVLV---HDDGKAKVSDFGLAK 1028
>14477
          Length = 493

 Score = 40.0 bits (92), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 39/149 (26%), Positives = 73/149 (48%), Gaps = 8/149 (5%)
 Frame = -1

Query: 22  KIGSGSFGDIYLAINITNGEEVAVKLESQKARHPQLLYESKLYKILQGGVGIPH---IRW 78
           K+G+G+FG +   +   +  E+ V ++  K        +S+L K  +    + H   +R 
Sbjct: 469 KLGAGNFGSVMKGVCRLDDREIPVAIKVLKNADLDPSVQSELIKEAEVMKKMDHMHIVRL 290

Query: 79  YGQ-EKDYNVLVMDL--LGPSLEDLFNFCSRRFTMKTVLMLADQMISRIEYVHTKNFIHR 135
            G  E +  +LV++L  LGP   + F   ++   +  +L L  Q+   +EY+    F+HR
Sbjct: 289 IGLCEGETMMLVLELAKLGPL--NKFLPKNKHLPLWNILELMWQVSQGMEYLEANKFVHR 116

Query: 136 DIKPDNFLMGIGRHCNKLF--LIDFGLAK 162
           D+   N L+     C++ F  + DFG++K
Sbjct: 115 DLAARNILL-----CDEHFAKISDFGMSK 44
>26009
          Length = 886

 Score = 38.9 bits (89), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 12/26 (46%), Positives = 22/26 (84%)
 Frame = +3

Query: 119 QMISRIEYVHTKNFIHRDIKPDNFLM 144
           Q++S ++++H+K  +HRDIKP+N L+
Sbjct: 735 QLVSALDFMHSKQLVHRDIKPENVLI 812
>12704
          Length = 641

 Score = 38.9 bits (89), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 14/31 (45%), Positives = 24/31 (77%)
 Frame = +3

Query: 17  YKLVRKIGSGSFGDIYLAINITNGEEVAVKL 47
           Y++VRK+G G + +++ AINITN E+  +K+
Sbjct: 537 YQIVRKLGRGKYSEVFEAINITNNEKCVIKI 629
>14420
          Length = 528

 Score = 38.1 bits (87), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 25/86 (29%), Positives = 42/86 (48%), Gaps = 2/86 (2%)
 Frame = +2

Query: 88  LVMDLL-GPSLEDLFN-FCSRRFTMKTVLMLADQMISRIEYVHTKNFIHRDIKPDNFLMG 145
           +VM+ L G SL D+    C     +  V     + +  +E++H    IHRDIK DN L+G
Sbjct: 131 VVMEFLAGGSLTDVVTETCMDEGQIAAV---CRECLQALEFLHENQVIHRDIKSDNILLG 301

Query: 146 IGRHCNKLFLIDFGLAKKYRDNRTRQ 171
           +      + L DFG   +    ++++
Sbjct: 302 MD---GSVKLTDFGFCAQLSPEQSKR 370
>27405
          Length = 532

 Score = 38.1 bits (87), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 37/156 (23%), Positives = 67/156 (42%), Gaps = 10/156 (6%)
 Frame = -3

Query: 28  FGDIYLAINITNGEEVAVKLESQK-----ARHPQLLYESKLYKILQGGVGIPHI---RWY 79
           FG++Y       G+  A+K   +K           L E  +  ++  G G P I    + 
Sbjct: 527 FGEVYGCRKADTGKMYAMKCLDKKRIKMKGGETLALNERIMLSLVSTGEGSPFIVCMTYA 348

Query: 80  GQEKDYNVLVMDLLGPSLEDLFNFCSRR--FTMKTVLMLADQMISRIEYVHTKNFIHRDI 137
            Q  +    ++DL+     DL    S+   FT K V   A +++  +E++H++  ++RD+
Sbjct: 347 FQTPEKLCFILDLMNGG--DLHYHLSQHGVFTEKEVRFYAAEVMLGLEHMHSRFVVYRDL 174

Query: 138 KPDNFLMGIGRHCNKLFLIDFGLAKKYRDNRTRQHI 173
           KP N L+    H     + D GLA  +   +    +
Sbjct: 173 KPANILLDENGHVR---ISDLGLACDFSKKKPHASV 75
>21433
          Length = 590

 Score = 37.7 bits (86), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 30/96 (31%), Positives = 41/96 (42%)
 Frame = +2

Query: 119 QMISRIEYVHTKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDNRTRQHIPYRED 178
           Q+ S +EY H +  IHRDIKP+N L+G+      L + DFG +          H P    
Sbjct: 191 QLSSALEYCHYRKVIHRDIKPENLLLGLK---GDLKIADFGWS---------VHAPSSRR 334

Query: 179 KNLTGTARYASINAHLGIEQSRRDDMESLGYVLMYF 214
             + GT  Y       G       D+ SLG +   F
Sbjct: 335 TTMCGTLDYLPPEMVEGKTHDENVDLWSLGVLCYEF 442
>30755
          Length = 1137

 Score = 37.0 bits (84), Expect = 0.012,   Method: Compositional matrix adjust.
 Identities = 26/84 (30%), Positives = 39/84 (46%), Gaps = 1/84 (1%)
 Frame = +2

Query: 105 SRRFTMKTVLMLADQMISRIEYVHTKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKY 164
            R FT +       ++IS + Y+H++  I+RD+K +N L+    H     + DFGL K  
Sbjct: 14  ERIFTEERTRFYGAEIISALGYLHSQGIIYRDLKLENLLLDKDGHIK---VADFGLCK-- 178

Query: 165 RDNRTRQHIPY-REDKNLTGTARY 187
                 + I Y R  K   GT  Y
Sbjct: 179 ------EDITYGRTTKTFCGTPEY 232
>21808
          Length = 1011

 Score = 36.6 bits (83), Expect = 0.013,   Method: Compositional matrix adjust.
 Identities = 27/119 (22%), Positives = 56/119 (47%), Gaps = 1/119 (0%)
 Frame = +1

Query: 50  QKARHPQLLYESKLYKILQGGVGIPHIRWYGQEKDYNVLVMDLL-GPSLEDLFNFCSRRF 108
           +K RHP+L+   +LY +               + D   ++ +L+   SL +      R  
Sbjct: 97  KKLRHPKLI---QLYAVCT-------------QDDPIFIITELMKNGSLLEFLQGKGRVL 228

Query: 109 TMKTVLMLADQMISRIEYVHTKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDN 167
            +  ++ +  Q+   + Y+ ++N+IHRD+   N L+      N + + DFGLA+  +++
Sbjct: 229 KLPALIDIGAQIACGMAYLESQNYIHRDLAARNILVSDN---NTVKIADFGLARVIKED 396
>28638
          Length = 1458

 Score = 36.6 bits (83), Expect = 0.015,   Method: Compositional matrix adjust.
 Identities = 28/98 (28%), Positives = 47/98 (47%), Gaps = 2/98 (2%)
 Frame = -1

Query: 117 ADQMISRIEYVHTK--NFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDNRTRQHIP 174
           A Q+ + + ++ T   N IH D+KP+N L+   +  + + ++DFG + +    R  Q+I 
Sbjct: 819 AQQLCTALLFLATPEMNIIHCDLKPENILLCNPKR-SAIKIVDFGSSCQL-GQRIYQYIQ 646

Query: 175 YREDKNLTGTARYASINAHLGIEQSRRDDMESLGYVLM 212
            R          Y S    LG+      DM SLG +L+
Sbjct: 645 SR---------FYRSPEVLLGVPYDLAIDMWSLGCILV 559
>19094
          Length = 898

 Score = 35.4 bits (80), Expect = 0.034,   Method: Compositional matrix adjust.
 Identities = 19/77 (24%), Positives = 37/77 (48%)
 Frame = +1

Query: 96  SLEDLFNFCSRRFTMKTVLMLADQMISRIEYVHTKNFIHRDIKPDNFLMGIGRHCNKLFL 155
           S+ D+    ++    + +  +    +  + Y+H++  IHRDIK  N L+    H     L
Sbjct: 13  SVSDIMRLRNKTLVEREIATILYYTLKGL*YLHSRRKIHRDIKAGNILLNNEGHAK---L 183

Query: 156 IDFGLAKKYRDNRTRQH 172
            DFG+A +  D   +++
Sbjct: 184 ADFGVAGQLTDTMAKRN 234
>26560
          Length = 398

 Score = 35.4 bits (80), Expect = 0.035,   Method: Compositional matrix adjust.
 Identities = 19/61 (31%), Positives = 33/61 (54%)
 Frame = -1

Query: 108 FTMKTVLMLADQMISRIEYVHTKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDN 167
           FT K V   A +++  +E++H++  ++RD+KP N L+    H     + D GLA  +   
Sbjct: 365 FTEKEVRFYAAEVMLGLEHMHSRFVVYRDLKPANILLDENGHVR---ISDLGLACDFSKK 195

Query: 168 R 168
           R
Sbjct: 194 R 192
>36481
          Length = 806

 Score = 35.0 bits (79), Expect = 0.039,   Method: Compositional matrix adjust.
 Identities = 32/137 (23%), Positives = 61/137 (44%), Gaps = 11/137 (8%)
 Frame = +2

Query: 18  KLVRKIGSGSFGDIYLAINITNGEEVAVKL--ESQKARHPQLLYESKLYKILQGGVGIPH 75
           KL    G G+FG +    ++  G+++A+K+     K R    L  + L K+ +      H
Sbjct: 371 KLCPHWGEGTFGKVVQCKDLLKGDDIALKIIKNVDKYREAAKLEINVLEKLREKDPHAKH 550

Query: 76  -----IRWYGQEKDYN---VLVMDLLGPSLEDLFNFCSR-RFTMKTVLMLADQMISRIEY 126
                + W+    DY+    +   +LG S+ D     S   + ++ V  ++ Q+   + +
Sbjct: 551 MCVQMLDWF----DYHGHVCISFHMLGLSVFDFLKDNSYGAYPIEQVRHISYQLCYAVNF 718

Query: 127 VHTKNFIHRDIKPDNFL 143
           +H     H D+KP+N L
Sbjct: 719 LHENQLTHTDLKPENIL 769
>01392
          Length = 1806

 Score = 35.0 bits (79), Expect = 0.043,   Method: Compositional matrix adjust.
 Identities = 27/93 (29%), Positives = 45/93 (48%), Gaps = 5/93 (5%)
 Frame = -1

Query: 124  IEYVHTKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKNLTG 183
            ++++H+K   HRD+KP+N L         + + DF LA     +      P  E     G
Sbjct: 1752 LDFLHSKGIAHRDLKPENILCEHLDDVVPVKICDFDLASGISCDGDGTKTP--ELLTPVG 1579

Query: 184  TARYAS---INAHLGIEQS--RRDDMESLGYVL 211
            +A Y +   ++A +G   S  +R D+ SLG +L
Sbjct: 1578 SAEYMAPEVVDAWVGDSFSYDKRCDLWSLGIIL 1480
>31489
          Length = 329

 Score = 34.7 bits (78), Expect = 0.051,   Method: Compositional matrix adjust.
 Identities = 20/65 (30%), Positives = 35/65 (53%)
 Frame = +3

Query: 79  YGQEKDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMISRIEYVHTKNFIHRDIK 138
           Y   KD +V V DL+   L  +  +  +  T + +     Q++  ++Y+H+ N +HRD+K
Sbjct: 75  YHDFKDIHV-VFDLMESDLHRII-YSDQPLTEEHIRYFLYQILRGLKYIHSANVVHRDLK 248

Query: 139 PDNFL 143
           P N L
Sbjct: 249 PSNLL 263
>00638
          Length = 1595

 Score = 34.7 bits (78), Expect = 0.052,   Method: Compositional matrix adjust.
 Identities = 12/28 (42%), Positives = 21/28 (75%)
 Frame = +1

Query: 17  YKLVRKIGSGSFGDIYLAINITNGEEVA 44
           Y++VRK+G G + +++ AIN+TN E+  
Sbjct: 139 YQIVRKLGRGKYSEVFEAINVTNNEKCV 222
>13212
          Length = 1067

 Score = 33.9 bits (76), Expect = 0.082,   Method: Compositional matrix adjust.
 Identities = 34/157 (21%), Positives = 65/157 (41%), Gaps = 7/157 (4%)
 Frame = -1

Query: 71   VGIPHIRWYGQEKDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMISRIEYVHTK 130
            V +  + W+G     + +++DL  P             T   +  +  +M   ++++H  
Sbjct: 1055 VDVFRVLWWGA---LDSIMVDLEKP------------MTEAQICYVCHEMCMALDFLHRH 921

Query: 131  NFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKNLTGTARYASI 190
            + IHRDIK  N L+ I     ++ L DFG++ K    + ++           GT  + + 
Sbjct: 920  HVIHRDIKAGNVLLTID---GEVKLADFGVSAKNTQTQQKRD-------TFIGTPYWMAP 771

Query: 191  NAHLGIEQSRRD-------DMESLGYVLMYFNRTSLP 220
               L   ++ +D       D+ SLG  L+ F +   P
Sbjct: 770  EVVLC--ETLKDTPYDFKADIWSLGVTLIEFAQIEPP 666
>17975
          Length = 449

 Score = 33.9 bits (76), Expect = 0.097,   Method: Compositional matrix adjust.
 Identities = 34/128 (26%), Positives = 59/128 (46%), Gaps = 12/128 (9%)
 Frame = +3

Query: 28  FGDIYLAINITNGEEVAVKLESQ----KARHPQLLYESKLYKILQGGVGIPHI-RWY--- 79
           F  + LA ++  GE+VAVK+  +    +     L  E +  K++Q     P++ R Y   
Sbjct: 6   FAVVKLARHVFTGEKVAVKVIDKTKLDEVSRSHLFQEVRCMKLVQH----PNVVRLYEVI 173

Query: 80  -GQEKDYNVLVMDLLGPSLEDLFNFCSRR---FTMKTVLMLADQMISRIEYVHTKNFIHR 135
             Q K Y +L +   G    D++++  R       K       Q++  I Y H  + +HR
Sbjct: 174 DTQTKLYLILELGDGG----DMYDYIMRHSGGLEEKLAKRYFRQIVEAISYCHKLHVVHR 341

Query: 136 DIKPDNFL 143
           D+KP+N +
Sbjct: 342 DLKPENVV 365
>28157
          Length = 400

 Score = 33.9 bits (76), Expect = 0.10,   Method: Compositional matrix adjust.
 Identities = 38/130 (29%), Positives = 64/130 (49%), Gaps = 9/130 (6%)
 Frame = +3

Query: 41  EEVAVK-LESQKARHPQLLYESKLYKILQGGVGIPHIRWYGQEKDYNV-LVMDLL-GPSL 97
           ++VAVK +ES++ +   +    +L ++    +    +  YG  +D+ V LVM+   G SL
Sbjct: 3   KDVAVKRIESEQEKKSFMQELKQLSRVSHPNI----VCLYGACRDHPVCLVMEYAEGGSL 170

Query: 98  EDLFNFC--SRRFTMKTVLMLADQMISRIEYVH---TKNFIHRDIKPDNFLMGIGRHC-N 151
            ++ +      ++T    +    Q    +EY+H    K  IHRD+KP N L+     C  
Sbjct: 171 YNVLHGSGPQPQYTAAHAMNWLLQCALGVEYLHGMKPKALIHRDLKPPNLLL---IQCGT 341

Query: 152 KLFLIDFGLA 161
           KL + DFG A
Sbjct: 342 KLKICDFGTA 371
>27546
          Length = 426

 Score = 33.1 bits (74), Expect = 0.16,   Method: Compositional matrix adjust.
 Identities = 17/48 (35%), Positives = 29/48 (60%)
 Frame = -1

Query: 119 QMISRIEYVHTKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRD 166
           QM   ++Y+H+ +  HRD+K +N L+   +  N + + DFG A+  RD
Sbjct: 156 QMAKALQYLHSHDIAHRDLKCENILL--SKRLN-VKIADFGFARYCRD 22
>13066
          Length = 551

 Score = 32.7 bits (73), Expect = 0.20,   Method: Compositional matrix adjust.
 Identities = 21/71 (29%), Positives = 36/71 (50%)
 Frame = +3

Query: 119 QMISRIEYVHTKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDNRTRQHIPYRED 178
           QM + + Y+H+ +  HRD+K +N L+    H N + L DFG A         +++     
Sbjct: 300 QMTTALNYLHSYDVAHRDLKCENILL--SSHFN-VKLADFGFACACITESGEKYM----S 458

Query: 179 KNLTGTARYAS 189
           +   G+A YA+
Sbjct: 459 RTYCGSAAYAA 491
>04138
          Length = 800

 Score = 32.7 bits (73), Expect = 0.20,   Method: Compositional matrix adjust.
 Identities = 20/57 (35%), Positives = 30/57 (52%)
 Frame = +1

Query: 111 KTVLMLADQMISRIEYVHTKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDN 167
           K++   AD+   R+ Y+H    +HRD+K  N L+        L L DFGLA+ +  N
Sbjct: 22  KSIC*AADE---RLYYIHRNKILHRDMKAANILIT---KQGVLKLADFGLARAFSVN 174
>21800
          Length = 855

 Score = 32.0 bits (71), Expect = 0.31,   Method: Compositional matrix adjust.
 Identities = 14/40 (35%), Positives = 24/40 (60%), Gaps = 1/40 (2%)
 Frame = +2

Query: 108 FTMKTVLMLADQMISRIEYVHTK-NFIHRDIKPDNFLMGI 146
             +  V ++  Q++  + Y+H K N IH DIKP+N L+ +
Sbjct: 623 IPVHNVKLIIRQVLEGLNYLHAKCNIIHTDIKPENILICV 742

 Score = 29.6 bits (65), Expect = 1.9,   Method: Compositional matrix adjust.
 Identities = 12/33 (36%), Positives = 21/33 (63%)
 Frame = +3

Query: 15  GKYKLVRKIGSGSFGDIYLAINITNGEEVAVKL 47
           G+Y +VRK+G G F  ++L  ++     VA+K+
Sbjct: 306 GRYHVVRKLGWGHFSTVWLCWDLNCKRFVALKV 404
>19301
          Length = 712

 Score = 30.4 bits (67), Expect = 0.89,   Method: Compositional matrix adjust.
 Identities = 13/33 (39%), Positives = 20/33 (60%)
 Frame = +2

Query: 113 VLMLADQMISRIEYVHTKNFIHRDIKPDNFLMG 145
           VL  + Q+ S + Y+H+   IHRD+K  N L+ 
Sbjct: 575 VLDWSKQIASGMNYLHSHKIIHRDLKSPNVLVA 673
>37602
          Length = 804

 Score = 29.3 bits (64), Expect = 2.3,   Method: Compositional matrix adjust.
 Identities = 13/51 (25%), Positives = 28/51 (54%)
 Frame = -1

Query: 94  GPSLEDLFNFCSRRFTMKTVLMLADQMISRIEYVHTKNFIHRDIKPDNFLM 144
           G S++D+++  +   T   +  +  + +  + Y+H +  +HRDIK  N L+
Sbjct: 267 GGSMQDIYHV-TGPLTEPQIAFVCRETLKGLHYLHRRGKMHRDIKGANILL 118

 Score = 28.1 bits (61), Expect = 5.0,   Method: Compositional matrix adjust.
 Identities = 10/24 (41%), Positives = 19/24 (79%)
 Frame = -2

Query: 17  YKLVRKIGSGSFGDIYLAINITNG 40
           ++L++++GSG++GD+Y A   T G
Sbjct: 503 FELIQRVGSGTYGDVYKAKA*TQG 432
>29360
          Length = 363

 Score = 29.3 bits (64), Expect = 2.3,   Method: Compositional matrix adjust.
 Identities = 16/67 (23%), Positives = 34/67 (50%), Gaps = 3/67 (4%)
 Frame = +3

Query: 81  QEKDYNVLVMDLLGPSLEDLFNFCSRRFT---MKTVLMLADQMISRIEYVHTKNFIHRDI 137
           Q K++  LV ++L  +L D       +F    +K +  +  Q+++ +  +     IH D+
Sbjct: 165 QHKNHTCLVFEMLEQNLYDFLK--QNKFQPLPLKYIRPITQQVLTALRKLKQLGLIHADL 338

Query: 138 KPDNFLM 144
           KP+N ++
Sbjct: 339 KPENIML 359
>07940
          Length = 1336

 Score = 28.9 bits (63), Expect = 2.6,   Method: Compositional matrix adjust.
 Identities = 18/57 (31%), Positives = 29/57 (50%)
 Frame = -3

Query: 106 RRFTMKTVLMLADQMISRIEYVHTKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAK 162
           +  T K ++  A Q+   +EY+ +K  IHRD+   N L+        L + DFGL +
Sbjct: 362 KMLTPKDLISYAYQVARGMEYLASKQCIHRDLAARNVLVA---EEYVLKIADFGLTR 201
>19761
          Length = 473

 Score = 28.9 bits (63), Expect = 2.8,   Method: Compositional matrix adjust.
 Identities = 27/94 (28%), Positives = 38/94 (40%), Gaps = 2/94 (2%)
 Frame = -3

Query: 119 QMISRIEYVHTKN--FIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDNRTRQHIPYR 176
           Q  S + Y+HT     +HRD+KP N  +        + L D GLA+K          P  
Sbjct: 399 QTASALNYMHTHTPVILHRDLKPQNIYV---TEKGDVRLGDLGLARKLTG-------PAD 250

Query: 177 EDKNLTGTARYASINAHLGIEQSRRDDMESLGYV 210
              +  GT  Y S         + + D+ SLG V
Sbjct: 249 FATSQVGTIMYLSPEILSQQPYNSKSDIWSLGCV 148
>14116
          Length = 1017

 Score = 27.7 bits (60), Expect = 6.4,   Method: Compositional matrix adjust.
 Identities = 15/54 (27%), Positives = 28/54 (51%)
 Frame = -1

Query: 109 TMKTVLMLADQMISRIEYVHTKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAK 162
           T+K ++M    +   ++Y+    F+HRD+   N ++    H     + DFGLA+
Sbjct: 327 TIKDLIMYGVDIARGMDYLAGLKFVHRDLAARNCMLDEDFHVK---VADFGLAR 175
>20559
          Length = 430

 Score = 27.7 bits (60), Expect = 6.6,   Method: Compositional matrix adjust.
 Identities = 13/31 (41%), Positives = 20/31 (64%)
 Frame = -2

Query: 16  KYKLVRKIGSGSFGDIYLAINITNGEEVAVK 46
           KY+ + KIG G++G ++ A N    E VA+K
Sbjct: 372 KYEKLEKIGEGTYGTVFKAKNRETHEIVALK 280
>20640
          Length = 1492

 Score = 27.7 bits (60), Expect = 6.7,   Method: Compositional matrix adjust.
 Identities = 23/82 (28%), Positives = 38/82 (46%)
 Frame = +1

Query: 130 KNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKNLTGTARYAS 189
           + ++HRD+   N L+G   H   + + DFGLA+            YR  ++     R+  
Sbjct: 1   RGYVHRDLATRNCLVG---HDLVVKISDFGLARSVHSVDY-----YRGSEHDAIPIRWMP 156

Query: 190 INAHLGIEQSRRDDMESLGYVL 211
           + A L  + S + D+ S G VL
Sbjct: 157 LEAILYNKFSTQSDVWSFGVVL 222
>12672
          Length = 773

 Score = 27.7 bits (60), Expect = 7.2,   Method: Compositional matrix adjust.
 Identities = 28/97 (28%), Positives = 39/97 (40%), Gaps = 6/97 (6%)
 Frame = +3

Query: 122 SRIEYVHTKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKN- 180
           S I+Y++    +HRDIK  N L+            D     K  D  T    P  E K  
Sbjct: 24  SGIQYLNDNGHVHRDIKTANILL------------DSEYTAKVGDFATVVSAPSGEGKTV 167

Query: 181 -----LTGTARYASINAHLGIEQSRRDDMESLGYVLM 212
                + GTA Y +  A +  + S + D  S G VL+
Sbjct: 168 QNASVVIGTAAYLAPEA-IHFDVSTKLDSYSFGVVLL 275
>32359
          Length = 928

 Score = 27.3 bits (59), Expect = 8.0,   Method: Compositional matrix adjust.
 Identities = 15/37 (40%), Positives = 20/37 (54%)
 Frame = -1

Query: 17  YKLVRKIGSGSFGDIYLAINITNGEEVAVKLESQKAR 53
           Y   + IG+GSFG +Y A  +   E VA+K   Q  R
Sbjct: 424 YTDAKVIGNGSFGVVYQAKLVDTSELVAIKKVLQDKR 314
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|144922656|ref|NP_663413.2| lethal giant larvae
homolog 2 [Mus musculus]
         (1027 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

11187                                                                 183   4e-46
08872                                                                 140   2e-33
06799                                                                  90   4e-18
30464                                                                  76   9e-14
05540                                                                  46   9e-05
02090                                                                  40   0.003
35607                                                                  40   0.005
01694                                                                  40   0.005
21921                                                                  35   0.19 
03156                                                                  32   1.0  
18562                                                                  31   2.3  
19863                                                                  30   4.8  
01327                                                                  30   5.0  
26336                                                                  29   9.4  
>11187
          Length = 1232

 Score =  183 bits (464), Expect = 4e-46,   Method: Compositional matrix adjust.
 Identities = 89/192 (46%), Positives = 131/192 (68%)
 Frame = +2

Query: 747 FSLRVPPAERRTDEPVRAEQAKEIQLMHRAPVVGILVLDGHNVPLPEPLEVAHDLSKSPD 806
           +SL VP +++R+ E V    AKEI+L H APV+ I V+D  N  LP+ LEV H+ +K+PD
Sbjct: 2   YSLTVPGSDKRSAEDVGCVLAKEIKLRHHAPVISIAVIDSKNRVLPDSLEVIHERAKAPD 181

Query: 807 MQGSHQLLVVSEEQFKVFTLPKVSAKLKLKLTALEGSRVRRVGVAHFGSCRAEDYGEHHL 866
           M+G H +++ SEEQ K FTLP +    K K+TA++GSR+RR+   +F S   ++Y EH +
Sbjct: 182 MEGQHSVVICSEEQLKAFTLPAMKPLWKTKVTAVDGSRLRRIAFVNFRSNSGDNYSEHDI 361

Query: 867 AVLTNLGDIQVVSMPLLKPQVRYSCIRREDVSGIASCVFTKYGQGFYLISPSEFERFSLS 926
             L + G++ V S+  L+ Q+R + +R+ED++G+AS VFTK GQG++L SPSEF   SLS
Sbjct: 362 VALNSQGELVVYSVKSLRCQLRSAAVRKEDINGMASFVFTKTGQGYFLQSPSEFGHVSLS 541

Query: 927 TKWLVEPRCLVD 938
           T    +P CLV+
Sbjct: 542 TSSCSKPECLVE 577
>08872
          Length = 466

 Score =  140 bits (354), Expect = 2e-33,   Method: Compositional matrix adjust.
 Identities = 69/161 (42%), Positives = 105/161 (65%)
 Frame = -2

Query: 19  DLFQFNKTVEHGFPHQPSALGYSPSLRILAIGTRSGAVKLYGAPGVEFMGLHKENNAVLQ 78
           +LF F K  +HGFP +PSAL + P L+++AIGT+SGAVK+YGAPGVEF G+HKE+ +V  
Sbjct: 465 ELFDFQKCADHGFPSKPSALAFDPKLKLIAIGTKSGAVKVYGAPGVEFSGVHKEDVSVTN 286

Query: 79  IHFLPGQCQLVTLLDDNSLHLWSLKVKGGVSELQEEESFTLRGPPGAAPSATQVTEILPH 138
           + FLP + +LV++  DN+LHLW + ++ G S ++E + F++        S   +T     
Sbjct: 285 LFFLPEEGRLVSVCSDNTLHLWEINLRSGQSVIEEVKEFSMENNKMKNVSTCCLT----- 121

Query: 139 SSGELLYLGTESGNVFVVQLPGFRTLHDRTICSDEVLQWLP 179
           +  + L LGTE GN+ ++ +  F TL D+ I  D V+Q +P
Sbjct: 120 ADSQNLLLGTEGGNIHILNIASF-TLADQIIYQDIVMQNVP 1
>06799
          Length = 616

 Score = 90.1 bits (222), Expect = 4e-18,   Method: Compositional matrix adjust.
 Identities = 67/220 (30%), Positives = 102/220 (46%), Gaps = 6/220 (2%)
 Frame = +3

Query: 81  FLPGQCQLVTLLDDNSLHLWSLKVKGGVSELQEEESFTLRGPPGAAPSATQVTEI-LPHS 139
           FL  +  LVT+  D++LHLW+ + K    E+     F             ++T   LP  
Sbjct: 6   FLINEGALVTVCADDTLHLWNYRQKK--PEIVHSLKF----------QRERITYCHLPFQ 149

Query: 140 SGELLYLGTESGNVFVVQLPGFRTLHDRTICSDEVLQWLPEEARHRRVFEM-VEALQEHP 198
           S + LY+GTE GNV +V +  F       I S  ++ W       R+     V  L ++P
Sbjct: 150 S-KWLYIGTERGNVHIVNIESF-------ILSGYIINWNKAIELSRKTHPGPVVHLSDNP 305

Query: 199 RDPNQILIGYSRGLVVIWDLQGSRALSHFLSSQQLENASWQRDGCLIVTCHSDGSHCQWP 258
            D N++LIG+  G +V+WDL+   A   + S + L + +W  +G   +  HSDGS   W 
Sbjct: 306 VDSNKLLIGFESGAIVLWDLRSKAAECRYNSPEALRSIAWHFEGKQFMCSHSDGSLTTWN 485

Query: 259 VSSDTQNPEPLRSSIPYG----PFPCKAITKIFWLTTRQG 294
           + +  +    L      G    P PCK ITK+ W + R G
Sbjct: 486 LKAPHKPANVLMPHAKVGAEGKPDPCKPITKVAWKSVRNG 605
>30464
          Length = 977

 Score = 75.9 bits (185), Expect = 9e-14,   Method: Composition-based stats.
 Identities = 38/96 (39%), Positives = 54/96 (56%), Gaps = 1/96 (1%)
 Frame = -3

Query: 364 IDLQTPGWPPVQLPYLASLHCSAITCSHHVSNIPLKLWERIIAAGSRQ-NSHFSTMEWPI 422
           +DL TPG+P  + PY   LH S +T   + +N P  L     + GSRQ  + FS   WPI
Sbjct: 966 VDLTTPGYPCFENPYPMDLHESPVTACQYYANCPTDLVPAFYSVGSRQKKTGFSEKAWPI 787

Query: 423 DGGTSLAPPPPQRDLLLTGHEDGTVRFWDASGVCLR 458
            GG          ++++TGH DG+++FWDAS V L+
Sbjct: 786 KGGQWGTTTVSYPEIIITGHADGSLKFWDASSVSLQ 679

 Score = 35.8 bits (81), Expect = 0.080,   Method: Compositional matrix adjust.
 Identities = 21/66 (31%), Positives = 34/66 (51%), Gaps = 5/66 (7%)
 Frame = -1

Query: 559 KGHERLAARPGPVCFEAGFQP-FVLVQC----QPPAVVTSLALHSEWRLVAFGTSHGFGL 613
           +G   +  R G   + AG+Q   V V C    +PP  +T ++L+S + L+AFG   G  +
Sbjct: 326 EGMTAVKVRGGARKWAAGYQADLVCVLCYVEGEPPGNITVMSLNSTYGLLAFGNESGLAI 147

Query: 614 FDHQQR 619
            D  Q+
Sbjct: 146 VDFIQK 129
>05540
          Length = 1260

 Score = 45.8 bits (107), Expect = 9e-05,   Method: Compositional matrix adjust.
 Identities = 22/45 (48%), Positives = 28/45 (62%)
 Frame = -1

Query: 904  VFTKYGQGFYLISPSEFERFSLSTKWLVEPRCLVDSTKAKKHNRP 948
            VFTK GQG++L SPSEF   SLST    +P CLV+  +  +   P
Sbjct: 1260 VFTKTGQGYFLQSPSEFGHVSLSTSSCSKPECLVELKEGMRPEPP 1126
>02090
          Length = 1841

 Score = 40.4 bits (93), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 33/115 (28%), Positives = 50/115 (43%)
 Frame = -3

Query: 19   DLFQFNKTVEHGFPHQPSALGYSPSLRILAIGTRSGAVKLYGAPGVEFMGLHKENNAVLQ 78
            DL +  +  +H F  Q  +LGY P+   LA+G  S  V++      +   LH   + VL 
Sbjct: 1416 DLREGRQLQQHDFSSQIFSLGYCPTGEWLAVGMESSNVEVLHHSKPDKYQLHLHESCVLS 1237

Query: 79   IHFLPGQCQLVTLLDDNSLHLWSLKVKGGVSELQEEESFTLRGPPGAAPSATQVT 133
            + F       V+   DN L+ W  +   G S  Q +ES ++     AA     VT
Sbjct: 1236 LKFAYCGKWFVSTGKDNLLNAW--RTPYGASIFQSKESSSVLSCDIAADDKYIVT 1078
>35607
          Length = 475

 Score = 40.0 bits (92), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 33/115 (28%), Positives = 50/115 (43%)
 Frame = +2

Query: 19  DLFQFNKTVEHGFPHQPSALGYSPSLRILAIGTRSGAVKLYGAPGVEFMGLHKENNAVLQ 78
           DL +  +  +H F  Q  +LGY P+   LA+G  S  V++      +   LH   + VL 
Sbjct: 62  DLREGRQLQQHDFSSQIFSLGYCPTGDWLAVGMESSNVEVLHHSKPDKYQLHLHESCVLS 241

Query: 79  IHFLPGQCQLVTLLDDNSLHLWSLKVKGGVSELQEEESFTLRGPPGAAPSATQVT 133
           + F       V+   DN L+ W  +   G S  Q +ES ++     AA     VT
Sbjct: 242 LKFAYCGKWFVSTGKDNLLNAW--RTPYGASIFQSKESSSVLSCDIAADDKYIVT 400
>01694
          Length = 944

 Score = 40.0 bits (92), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 33/139 (23%), Positives = 61/139 (43%), Gaps = 22/139 (15%)
 Frame = -2

Query: 813 LLVVSEEQFKVFTLPKVSAKLKLKLTALEGSRVRRVGVAHFGSCRAEDYGEHHLAV---- 868
           +++ SE+Q KVF +       +++L+ ++ +          GSC A      HL V    
Sbjct: 919 IVIASEKQTKVFDVANQCCINRIQLSEMDFAVKAETITMKDGSCLATYLSNGHLMVHSLP 740

Query: 869 -LTNLGDIQVVSMPLLKPQVRYSC----------------IRREDVSGIASC-VFTKYGQ 910
            L  L D     +PL++   +  C                I  ED + I+    F+  G 
Sbjct: 739 SLKLLLDTDF--LPLMELSFQTKCKQGIVDPMLSIWGQQIIVHEDTTQISKIFCFSHKGH 566

Query: 911 GFYLISPSEFERFSLSTKW 929
           G Y+ SP+E ++F++S+++
Sbjct: 565 GLYMASPTEIQKFTISSEF 509
>21921
          Length = 1341

 Score = 34.7 bits (78), Expect = 0.19,   Method: Compositional matrix adjust.
 Identities = 18/52 (34%), Positives = 30/52 (57%), Gaps = 1/52 (1%)
 Frame = -1

Query: 431 PPPQRDLLLTGHEDGTVRFWD-ASGVCLRLLYKLSTVRVFLTDTDPSENLIA 481
           P P    L++G +DGT+RFW+ +SG C++ L     V     + +PS  ++A
Sbjct: 459 PDPTGQWLVSGSDDGTIRFWEVSSGRCMKTLQVGGCVTSVAWNPNPSLCVVA 304
>03156
          Length = 1014

 Score = 32.3 bits (72), Expect = 1.0,   Method: Composition-based stats.
 Identities = 22/54 (40%), Positives = 30/54 (55%), Gaps = 4/54 (7%)
 Frame = +1

Query: 437 LLLTGHEDGTVRFWDA-SGVCLRLLYKLSTVRVFLTDTD--PSENLIAQ-GEDE 486
           LL +G  D TVR WD  +G CLR   + +  +  +TD    P  +LI Q GED+
Sbjct: 223 LLCSGSRDNTVRIWDVETGACLR---QNNIPQNLVTDVKWLPGSHLIIQAGEDK 375
>18562
          Length = 414

 Score = 31.2 bits (69), Expect = 2.3,   Method: Compositional matrix adjust.
 Identities = 15/29 (51%), Positives = 18/29 (62%)
 Frame = +1

Query: 565 AARPGPVCFEAGFQPFVLVQCQPPAVVTS 593
             RPGPV +E G  P +LV C P + VTS
Sbjct: 295 VVRPGPVSWEEGVGPALLVSCGPVSRVTS 381
>19863
          Length = 502

 Score = 30.0 bits (66), Expect = 4.8,   Method: Composition-based stats.
 Identities = 12/41 (29%), Positives = 24/41 (58%)
 Frame = +1

Query: 63  GVEFMGLHKENNAVLQIHFLPGQCQLVTLLDDNSLHLWSLK 103
           GV+ + L      V  +HF   QC L++  +DN++ +W+++
Sbjct: 67  GVQKLRLQGHAGWVNDVHFSQDQCWLLSCSNDNTVRIWNIE 189
>01327
          Length = 2215

 Score = 30.0 bits (66), Expect = 5.0,   Method: Compositional matrix adjust.
 Identities = 22/54 (40%), Positives = 30/54 (55%), Gaps = 4/54 (7%)
 Frame = +3

Query: 437 LLLTGHEDGTVRFWDA-SGVCLRLLYKLSTVRVFLTDTD--PSENLIAQ-GEDE 486
           LL +G  D TVR WD  +G CLR   + +  +  +TD    P  +LI Q GED+
Sbjct: 333 LLCSGSRDNTVRIWDVETGACLR---QNNIPQNLVTDVKWLPGSHLIIQAGEDK 485
>26336
          Length = 1465

 Score = 29.3 bits (64), Expect = 9.4,   Method: Composition-based stats.
 Identities = 15/40 (37%), Positives = 21/40 (52%)
 Frame = +2

Query: 675 EAQAQAVNIKAERTGLQNMELAPVQRKIEARSAEDSFTGF 714
           E Q  +    A+ TG QN++LAP   K + R +E   T F
Sbjct: 53  ERQKNSPETSAD*TGFQNLKLAPESNKNDPRVSEAMVTNF 172
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|118403314|ref|NP_573505.2| RNA binding motif protein
39 [Mus musculus]
         (530 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

07815                                                                 181   5e-46
07938                                                                 158   4e-39
34189                                                                  90   2e-18
03000                                                                  81   1e-15
10060                                                                  66   3e-15
31310                                                                  76   3e-14
17775                                                                  71   9e-13
19868                                                                  67   3e-11
24881                                                                  64   1e-10
10194                                                                  64   2e-10
11687                                                                  62   4e-10
13822                                                                  62   7e-10
03406                                                                  61   1e-09
23322                                                                  58   8e-09
32386                                                                  55   5e-08
33516                                                                  55   6e-08
31618                                                                  55   6e-08
17681                                                                  55   6e-08
02415                                                                  55   8e-08
01278                                                                  54   2e-07
28652                                                                  53   3e-07
24983                                                                  51   1e-06
20488                                                                  51   1e-06
16427                                                                  50   2e-06
03744                                                                  49   4e-06
00556                                                                  49   5e-06
12350                                                                  49   5e-06
30672                                                                  47   1e-05
14258                                                                  47   2e-05
26197                                                                  47   2e-05
13457                                                                  47   2e-05
11019                                                                  46   3e-05
08958                                                                  46   4e-05
23720                                                                  45   5e-05
04988                                                                  45   5e-05
03903                                                                  45   5e-05
14637                                                                  45   9e-05
02343                                                                  45   1e-04
15503                                                                  44   2e-04
21096                                                                  44   2e-04
32733                                                                  43   3e-04
25691                                                                  43   3e-04
03200                                                                  42   5e-04
05273                                                                  42   7e-04
23655                                                                  40   0.003
23250                                                                  39   0.004
25950                                                                  39   0.007
00029                                                                  38   0.009
29364                                                                  38   0.011
28455                                                                  38   0.013
11126                                                                  37   0.024
15371                                                                  37   0.026
11108                                                                  36   0.047
00741                                                                  35   0.093
16016                                                                  35   0.094
03097                                                                  35   0.098
09736                                                                  34   0.12 
16936                                                                  33   0.40 
28372                                                                  32   0.53 
19733                                                                  32   0.84 
28605                                                                  31   1.1  
25632                                                                  29   3.7  
32980                                                                  29   4.6  
35180                                                                  28   8.3  
02140                                                                  28   9.0  
>07815
          Length = 1483

 Score =  181 bits (460), Expect = 5e-46,   Method: Compositional matrix adjust.
 Identities = 102/215 (47%), Positives = 121/215 (56%), Gaps = 2/215 (0%)
 Frame = -2

Query: 318  GRPMKVGHVTER-TDXXXXXXXXXXXXXXRTGIDLGTTGRLQLMARLAEGTG-XXXXXXX 375
            GR MKVG+VTER                 R GIDLG TGRLQLMA+LAEGTG        
Sbjct: 1479 GRAMKVGNVTERGLLEGAPNSALDTDEMDRAGIDLGATGRLQLMAKLAEGTGFQIPQYAA 1300

Query: 376  XXXXXMSGSLAFGAVAEFSFVIDLQTRXXXXXXXXXXXXXXXXXXXXTQCFQLSNMFNPQ 435
                 + GS A G +        L +                     TQCF LSNMF+  
Sbjct: 1299 SALSQVGGSQAAGMLNMPQPFTQLPS--IADPANGPPTSNIPAPPITTQCFMLSNMFDAG 1126

Query: 436  TEEEVGWDTEIKDDVIEECNKHGGVIHIYVDKNSAQGNVYVKCPSXXXXXXXVNALHGRW 495
             E    W+ EI+DDVIEECNKHGGV+HI+ DK+S QGNVYVKCP+       VNALHGR+
Sbjct: 1125 GENRPTWEQEIRDDVIEECNKHGGVLHIFTDKSSPQGNVYVKCPTIAAAAASVNALHGRY 946

Query: 496  FAGKMITAAYVPLPTYHNLFPDSMTATQLLVPSRR 530
            F G++ITAAYVPLP Y +LFPDS   +Q L+ S +
Sbjct: 945  FGGRLITAAYVPLPNYSSLFPDSARLSQPLLSSAQ 841
>07938
          Length = 938

 Score =  158 bits (400), Expect = 4e-39,   Method: Compositional matrix adjust.
 Identities = 66/108 (61%), Positives = 85/108 (78%)
 Frame = +1

Query: 423 TQCFQLSNMFNPQTEEEVGWDTEIKDDVIEECNKHGGVIHIYVDKNSAQGNVYVKCPSXX 482
           TQCF LSNMF+P+TE    WDTE++DDVI+EC KHGGV+HI+VD  S  G VYVKCPS  
Sbjct: 130 TQCFILSNMFDPRTETNPAWDTEVRDDVIDECTKHGGVLHIHVDTVSPTGTVYVKCPSTT 309

Query: 483 XXXXXVNALHGRWFAGKMITAAYVPLPTYHNLFPDSMTATQLLVPSRR 530
                VN+LHGRWFAG++ITAAYVPL  YH++FPD+++A+ L+  +R+
Sbjct: 310 TAVLAVNSLHGRWFAGRVITAAYVPLINYHSMFPDAISASDLIASTRK 453
>34189
          Length = 347

 Score = 90.1 bits (222), Expect = 2e-18,   Method: Composition-based stats.
 Identities = 41/69 (59%), Positives = 50/69 (72%)
 Frame = +1

Query: 460 VIHIYVDKNSAQGNVYVKCPSXXXXXXXVNALHGRWFAGKMITAAYVPLPTYHNLFPDSM 519
           V+HIYVDK+S  GNVYVKC S       VN+LHGR+F G++I AAYVPLP Y  LF +S+
Sbjct: 1   VVHIYVDKSSPMGNVYVKCTSIAAAVASVNSLHGRYFGGRVINAAYVPLPNYATLFVESV 180

Query: 520 TATQLLVPS 528
            ATQ L+ S
Sbjct: 181 RATQPLMTS 207
>03000
          Length = 778

 Score = 80.9 bits (198), Expect = 1e-15,   Method: Compositional matrix adjust.
 Identities = 50/189 (26%), Positives = 93/189 (49%), Gaps = 1/189 (0%)
 Frame = +3

Query: 144 NLTPEERDARTVFCMQLAARIRPRDLEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEFVD 203
           +L P     R +F   L+       L   F T G++ D  ++ D NS+RS+G  ++ + D
Sbjct: 60  DLDPNAEQFRKLFIGGLSYETDEDSLRSHFETWGEIVDCIVMRDSNSKRSRGFGFITYKD 239

Query: 204 VSSVPLAIGLTGQRVLGVPIIVQ-ASQAEKNRAAAMANNLQKGSAGPMRLYVGSLHFNIT 262
             S+  A      ++ G  +  + A   E++  + +  +++K       ++VG +  + T
Sbjct: 240 AESIDQAQANRPHKIDGREVDTKRAMPREESGRSEVQQSVKK-------MFVGGVKEDTT 398

Query: 263 EDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECAKKALEQLNGFELAGRPMK 322
           EDM+R  F  FG I  + L+ D  TG+++G+ F+TF D +   KA+ +    +L GR ++
Sbjct: 399 EDMIRDTFNEFGEITGVDLIQDKGTGKNRGFCFVTFGDHDSVDKAVLKKR-HDLNGRQVE 575

Query: 323 VGHVTERTD 331
           V     + D
Sbjct: 576 VKKAQSKND 602
>10060
          Length = 367

 Score = 66.2 bits (160), Expect(2) = 3e-15,   Method: Compositional matrix adjust.
 Identities = 28/41 (68%), Positives = 31/41 (75%)
 Frame = -2

Query: 423 TQCFQLSNMFNPQTEEEVGWDTEIKDDVIEECNKHGGVIHI 463
           TQCF LSNMF+   E    W  EI+DDVIEECNKHGGV+HI
Sbjct: 180 TQCFMLSNMFDAGGENRPTWKQEIRDDVIEECNKHGGVLHI 58

 Score = 33.5 bits (75), Expect(2) = 3e-15,   Method: Composition-based stats.
 Identities = 12/17 (70%), Positives = 15/17 (88%)
 Frame = -1

Query: 464 YVDKNSAQGNVYVKCPS 480
           + DK+S QGNVYVKCP+
Sbjct: 58  FTDKSSPQGNVYVKCPT 8

 Score = 44.7 bits (104), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 20/23 (86%), Positives = 21/23 (91%)
 Frame = -3

Query: 346 RTGIDLGTTGRLQLMARLAEGTG 368
           R GIDLG TGRLQLMA+LAEGTG
Sbjct: 311 RAGIDLGATGRLQLMAKLAEGTG 243
>31310
          Length = 469

 Score = 76.3 bits (186), Expect = 3e-14,   Method: Compositional matrix adjust.
 Identities = 37/82 (45%), Positives = 52/82 (63%)
 Frame = -3

Query: 243 QKGSAGPMRLYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSE 302
           Q+  A   R+YVGS++F I ED ++  F PFG I+S+ L  D  T + KG+ FI +   E
Sbjct: 344 QQALALMCRIYVGSINFEIREDTIKQAFLPFGPIKSVNLSWDPITNKHKGFSFIEYDVPE 165

Query: 303 CAKKALEQLNGFELAGRPMKVG 324
            A+ ALEQ+NG  + GR +KVG
Sbjct: 164 AAQLALEQMNGVMIGGRNIKVG 99

 Score = 29.6 bits (65), Expect = 3.2,   Method: Compositional matrix adjust.
 Identities = 23/100 (23%), Positives = 45/100 (45%), Gaps = 4/100 (4%)
 Frame = -3

Query: 164 IRPRDLEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEFVDVSSVPLAIGLTGQRVLGVPI 223
           IR   +++ F   G ++ V +  D  + + KG +++E+     VP A  L  +++ GV I
Sbjct: 290 IREDTIKQAFLPFGPIKSVNLSWDPITNKHKGFSFIEY----DVPEAAQLALEQMNGVMI 123

Query: 224 ----IVQASQAEKNRAAAMANNLQKGSAGPMRLYVGSLHF 259
               I     +   +A  +   L   +    R+Y+ S+H 
Sbjct: 122 GGRNIKVGRPSNMPQAQPIIEQLAMEATHYFRIYIASIHL 3
>17775
          Length = 1282

 Score = 71.2 bits (173), Expect = 9e-13,   Method: Compositional matrix adjust.
 Identities = 52/164 (31%), Positives = 80/164 (48%), Gaps = 1/164 (0%)
 Frame = -2

Query: 169  LEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEFVDVSSVPLAIG-LTGQRVLGVPIIVQA 227
            L E FST G V  +R+  D  +RRS G AYV F   +    A+  +    V G PI +  
Sbjct: 1146 LFEKFSTAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDTMNFDTVKGRPIRIMW 967

Query: 228  SQAEKNRAAAMANNLQKGSAGPMRLYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSET 287
            SQ + +        ++K   G   +++ +L   I    L   F  FG I S ++  D + 
Sbjct: 966  SQRDPS--------VRKSGVG--NVFIKNLDKTIDNKALYDTFSAFGNILSCKIACDEQG 817

Query: 288  GRSKGYGFITFSDSECAKKALEQLNGFELAGRPMKVGHVTERTD 331
              SKGYGF+ F   E A++A++++NG  L G+ + VG    R +
Sbjct: 816  --SKGYGFVHFETEEAARQAIDKVNGMLLNGKKVYVGRFIPRKE 691

 Score = 64.7 bits (156), Expect = 9e-11,   Method: Compositional matrix adjust.
 Identities = 45/147 (30%), Positives = 71/147 (48%), Gaps = 7/147 (4%)
 Frame = -2

Query: 192 RSKGIAYVEFVDVSSVPLAIG-LTGQRVLGVPIIVQASQAEKNRAAAMANNLQK------ 244
           +S+G  +V F +      A+  + G  V G  I    +Q    R A +    +K      
Sbjct: 537 KSRGFGFVSFEEPEGAEKAVDEINGTEVSGRIIYCGRAQKRAERQAELKERFEKIKLERI 358

Query: 245 GSAGPMRLYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECA 304
                + LYV +L  +I ++ LR  F  FG I S ++M  +E GRSKG+GF+ FS  E A
Sbjct: 357 NRYQGVNLYVKNLDDSIDDERLRKEFSNFGTITSAKIM--TEGGRSKGFGFVCFSSPEEA 184

Query: 305 KKALEQLNGFELAGRPMKVGHVTERTD 331
            KA+ ++NG  +  +P+ V     + D
Sbjct: 183 TKAVTEMNGRIIVAKPLYVALAQRKED 103

 Score = 55.8 bits (133), Expect = 4e-08,   Method: Compositional matrix adjust.
 Identities = 31/80 (38%), Positives = 47/80 (58%), Gaps = 1/80 (1%)
 Frame = -2

Query: 245  GSAGPM-RLYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSEC 303
            G + PM  LYVG LH ++TE ML   F   G + SI++  D  T RS GY ++ F     
Sbjct: 1212 GPSYPMASLYVGDLHPDVTEAMLFEKFSTAGPVLSIRVCRDMITRRSLGYAYVNFQQPAD 1033

Query: 304  AKKALEQLNGFELAGRPMKV 323
            A++AL+ +N   + GRP+++
Sbjct: 1032 AERALDTMNFDTVKGRPIRI 973

 Score = 46.2 bits (108), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 18/46 (39%), Positives = 34/46 (73%)
 Frame = -2

Query: 286 ETGRSKGYGFITFSDSECAKKALEQLNGFELAGRPMKVGHVTERTD 331
           E G+S+G+GF++F + E A+KA++++NG E++GR +  G   +R +
Sbjct: 546 EDGKSRGFGFVSFEEPEGAEKAVDEINGTEVSGRIIYCGRAQKRAE 409
>19868
          Length = 434

 Score = 66.6 bits (161), Expect = 3e-11,   Method: Compositional matrix adjust.
 Identities = 38/151 (25%), Positives = 72/151 (47%)
 Frame = +2

Query: 155 VFCMQLAARIRPRDLEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEFVDVSSVPLAIGLT 214
           +F   L+ +  P  L ++F+  G++ +V ++ D  +RRS+G  ++ F D +SV   +   
Sbjct: 5   MFVGGLSWQTSPESLRDYFNKFGEITEVMVMKDPTTRRSRGFGFITFGDPASVDKVLAQA 184

Query: 215 GQRVLGVPIIVQASQAEKNRAAAMANNLQKGSAGPMRLYVGSLHFNITEDMLRGIFEPFG 274
              + G  I  + +   +     +            +++VG L    T + ++  FE FG
Sbjct: 185 THELDGKKIDPKVAFPRRAHPRMVTRT--------KKIFVGGLSAPTTLEDVKNYFEQFG 340

Query: 275 RIESIQLMMDSETGRSKGYGFITFSDSECAK 305
            IE   LM D +T R +G+GF+T S    ++
Sbjct: 341 PIEDAMLMFDKQTNRHRGFGFVTISKRRHSR 433

 Score = 53.5 bits (127), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 27/69 (39%), Positives = 38/69 (55%)
 Frame = +2

Query: 251 RLYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECAKKALEQ 310
           +++VG L +  + + LR  F  FG I  + +M D  T RS+G+GFITF D     K L Q
Sbjct: 2   KMFVGGLSWQTSPESLRDYFNKFGEITEVMVMKDPTTRRSRGFGFITFGDPASVDKVLAQ 181

Query: 311 LNGFELAGR 319
               EL G+
Sbjct: 182 AT-HELDGK 205
>24881
          Length = 627

 Score = 64.3 bits (155), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 31/89 (34%), Positives = 51/89 (57%)
 Frame = +1

Query: 423 TQCFQLSNMFNPQTEEEVGWDTEIKDDVIEECNKHGGVIHIYVDKNSAQGNVYVKCPSXX 482
           T C ++ NMF+ + E E  W+  ++D ++E+C     ++ I+VD  S +G VYVKC S  
Sbjct: 361 TPCLKIRNMFDKEVESEENWEESVRDALLEKCRDIKSLVQIFVDHRSKEGCVYVKCNSKE 540

Query: 483 XXXXXVNALHGRWFAGKMITAAYVPLPTY 511
                  ALHG WF G+++T  ++ +  Y
Sbjct: 541 AAGKVRQALHGWWFDGRLVTVKHIKVEHY 627
>10194
          Length = 1278

 Score = 63.5 bits (153), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 51/190 (26%), Positives = 86/190 (45%), Gaps = 17/190 (8%)
 Frame = -3

Query: 151 DARTVFCMQLAARIRPRDLEEFFSTVGKVRDVR-----------------MISDRNSRRS 193
           + RTVF   +  +   + L   F   GK+ +VR                 +  D + +R 
Sbjct: 718 EKRTVFVGNVPLKTDKKKLARLFKQFGKIENVRFRCAPVGDPTTKKRVAVITKDFHEKRH 539

Query: 194 KGIAYVEFVDVSSVPLAIGLTGQRVLGVPIIVQASQAEKNRAAAMANNLQKGSAGPMRLY 253
              AY+ F +  +   A+ L G  + G+ + V +       A     NL K S     ++
Sbjct: 538 NISAYICFKEDEAAKQALTLNGHVIDGLHLRVDS-------AKLSLKNLDKRS-----VF 395

Query: 254 VGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECAKKALEQLNG 313
           VG+L F+I E+ +R  FE  G +E+I+++ D +T   KG  +I F  ++    AL +LN 
Sbjct: 394 VGNLPFDIEEESVRSHFEDCGDVENIRVVRDRKTNLGKGICYILFKSADSVSLAL-KLNN 218

Query: 314 FELAGRPMKV 323
            EL  R ++V
Sbjct: 217 SELEKRQIRV 188
>11687
          Length = 676

 Score = 62.4 bits (150), Expect = 4e-10,   Method: Compositional matrix adjust.
 Identities = 43/165 (26%), Positives = 81/165 (49%), Gaps = 3/165 (1%)
 Frame = +3

Query: 151 DARTVFCMQLAARIRPRDLEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEFVDVSSVPLA 210
           D+  +F  Q+   +   +L + F   G V  + ++ D+N+ +SKG  +V F       L 
Sbjct: 144 DSIKMFVGQIPRNMDENELRKMFEDYGPVHSLNILRDKNTGQSKGCCFVTFF-TRKAALD 320

Query: 211 IGLTGQRVLGVPII---VQASQAEKNRAAAMANNLQKGSAGPMRLYVGSLHFNITEDMLR 267
                  V  +P++   VQ   A+  +     N  ++      +L+VG L   ++E+ +R
Sbjct: 321 AQNALHNVKTMPMMHHPVQMKPADSEKRNGERNVEER------KLFVGMLSKKLSENDVR 482

Query: 268 GIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECAKKALEQLN 312
            +FE FG I+   ++ DS  G S+G  FITF+  +CA  +++ ++
Sbjct: 483 MLFESFGSIDDCTVLRDS-NGTSRGCAFITFASRQCAMNSIKGMH 614

 Score = 49.7 bits (117), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 24/80 (30%), Positives = 46/80 (57%), Gaps = 3/80 (3%)
 Frame = +3

Query: 247 AGPMRLYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSEC--- 303
           A  ++++VG +  N+ E+ LR +FE +G + S+ ++ D  TG+SKG  F+TF   +    
Sbjct: 141 ADSIKMFVGQIPRNMDENELRKMFEDYGPVHSLNILRDKNTGQSKGCCFVTFFTRKAALD 320

Query: 304 AKKALEQLNGFELAGRPMKV 323
           A+ AL  +    +   P+++
Sbjct: 321 AQNALHNVKTMPMMHHPVQM 380
>13822
          Length = 963

 Score = 61.6 bits (148), Expect = 7e-10,   Method: Compositional matrix adjust.
 Identities = 32/82 (39%), Positives = 53/82 (64%)
 Frame = -1

Query: 248 GPMRLYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECAKKA 307
           GP RL+V ++ F   E  LR +  PFG I  ++++ + E G SKG+GF+TF+ S  A++A
Sbjct: 348 GPKRLHVSNIPFRFREADLRQLLGPFGTILDVEIIFN-ERG-SKGFGFVTFAHSAEAERA 175

Query: 308 LEQLNGFELAGRPMKVGHVTER 329
            +++NG  + GR ++V + T R
Sbjct: 174 RDKMNGTVVEGRKIEVNNATAR 109
>03406
          Length = 1292

 Score = 60.8 bits (146), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 39/180 (21%), Positives = 81/180 (45%)
 Frame = +3

Query: 148 EERDARTVFCMQLAARIRPRDLEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEFVDVSSV 207
           E  D R +F   L+     + L E+F   G+V    + +D +S +S+G  +V F + ++V
Sbjct: 225 ENEDDRKIFVGGLSWETXSKHLREYFEKFGEVTSCTLKTDLDSGKSRGFGFVVFKEAATV 404

Query: 208 PLAIGLTGQRVLGVPIIVQASQAEKNRAAAMANNLQKGSAGPMRLYVGSLHFNITEDMLR 267
              +     ++ G  I  + +   K               G  +++VG L   + ++ + 
Sbjct: 405 DAVVKNKEHKLQGRKIDPKPANPRK---------------GMRKIFVGKLDPGVPQEDVE 539

Query: 268 GIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECAKKALEQLNGFELAGRPMKVGHVT 327
             F  FG++ +++L  D    + + + F+ F + +  KK LEQ +  ++ G+ + V   T
Sbjct: 540 SYFAKFGKVVNVELPYDKVKDQRRAFCFVEFDNDKTVKKVLEQTS-HKIGGQEVDVKKAT 716

 Score = 47.0 bits (110), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 19/69 (27%), Positives = 38/69 (55%)
 Frame = +3

Query: 233 NRAAAMANNLQKGSAGPMRLYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSKG 292
           ++A     + ++ +    +++VG L +      LR  FE FG + S  L  D ++G+S+G
Sbjct: 189 DQAMETGGDAEEENEDDRKIFVGGLSWETXSKHLREYFEKFGEVTSCTLKTDLDSGKSRG 368

Query: 293 YGFITFSDS 301
           +GF+ F ++
Sbjct: 369 FGFVVFKEA 395
>23322
          Length = 471

 Score = 58.2 bits (139), Expect = 8e-09,   Method: Compositional matrix adjust.
 Identities = 27/81 (33%), Positives = 47/81 (58%)
 Frame = -2

Query: 251 RLYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECAKKALEQ 310
           +++VG +  + TEDM+R  F  FG I  + L+ D  TG+++G+ F+TF D +   KA+ +
Sbjct: 407 KMFVGGVKEDTTEDMIRDTFNEFGEITGVDLIQDKGTGKNRGFCFVTFGDHDSVDKAVLK 228

Query: 311 LNGFELAGRPMKVGHVTERTD 331
               +L GR ++V     + D
Sbjct: 227 KR-HDLNGRQVEVKKAQSKND 168
>32386
          Length = 674

 Score = 55.5 bits (132), Expect = 5e-08,   Method: Compositional matrix adjust.
 Identities = 28/73 (38%), Positives = 41/73 (56%)
 Frame = +1

Query: 251 RLYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECAKKALEQ 310
           +L++G L +   ED LR  FE +G I    +M DS + RS+G+GFIT+ D+E   +A   
Sbjct: 304 KLFIGGLSYETDEDSLRSHFETWGEIVDCIVMRDSNSKRSRGFGFITYKDAESIDQA--- 474

Query: 311 LNGFELAGRPMKV 323
                 A RP K+
Sbjct: 475 -----QANRPHKI 498
>33516
          Length = 449

 Score = 55.5 bits (132), Expect = 6e-08,   Method: Composition-based stats.
 Identities = 22/56 (39%), Positives = 37/56 (66%)
 Frame = +1

Query: 245 GSAGPMRLYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSD 300
           G   P +++VG L ++  +D L+G F  FG I    +MM+ +TG+S+G+GF++F D
Sbjct: 139 GREEPGKIFVGGLSWDTDQDSLQGYFSQFGEITDCIVMMNQQTGKSRGFGFVSFKD 306
>31618
          Length = 716

 Score = 55.5 bits (132), Expect = 6e-08,   Method: Compositional matrix adjust.
 Identities = 27/65 (41%), Positives = 42/65 (64%)
 Frame = +1

Query: 251 RLYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECAKKALEQ 310
           +L+VG L +  TE  LR  F  +G IESI +  D +TGRS+G+ FI F+++E    A++Q
Sbjct: 295 KLFVGGLSWETTEKELRDHFGKYGEIESINVKTDPQTGRSRGFAFIVFTNTE----AIDQ 462

Query: 311 LNGFE 315
           ++  E
Sbjct: 463 VSAAE 477

 Score = 28.9 bits (63), Expect = 5.8,   Method: Compositional matrix adjust.
 Identities = 31/150 (20%), Positives = 61/150 (40%)
 Frame = +1

Query: 160 LAARIRPRDLEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEFVDVSSVPLAIGLTGQRVL 219
           L+     ++L + F   G++  + + +D  + RS+G A++ F +  ++   +    + ++
Sbjct: 313 LSWETTEKELRDHFGKYGEIESINVKTDPQTGRSRGFAFIVFTNTEAID-QVSAAEEHII 489

Query: 220 GVPIIVQASQAEKNRAAAMANNLQKGSAGPMRLYVGSLHFNITEDMLRGIFEPFGRIESI 279
                 +    +K    AMA  L    A P RL +       T   L  I E       +
Sbjct: 490 NS----KKVDPKKKPRLAMARFL--SVA*PQRLAMRKS--KPTSVNLDNIVE-------V 624

Query: 280 QLMMDSETGRSKGYGFITFSDSECAKKALE 309
           ++  D +    KG+ FITF   +     L+
Sbjct: 625 EMPFDKQKSHRKGFXFITFDSEQVVTDLLK 714
>17681
          Length = 964

 Score = 55.5 bits (132), Expect = 6e-08,   Method: Compositional matrix adjust.
 Identities = 25/79 (31%), Positives = 44/79 (55%)
 Frame = +2

Query: 251 RLYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECAKKALEQ 310
            ++VG L   I  + LR  F PFG I + +++ D +T +SKGY F++F     A+ A++ 
Sbjct: 35  HIFVGDLSPEIETETLREAFAPFGEISNCRIVRDPQTMKSKGYAFVSFVKKAEAENAIQA 214

Query: 311 LNGFELAGRPMKVGHVTER 329
           +NG  +  R ++    T +
Sbjct: 215 MNGQWIGSRSIRTNWSTRK 271
>02415
          Length = 2763

 Score = 55.1 bits (131), Expect = 8e-08,   Method: Compositional matrix adjust.
 Identities = 23/62 (37%), Positives = 40/62 (64%)
 Frame = -1

Query: 251  RLYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECAKKALEQ 310
            +++VG L ++ T+  LR  F+ FG I+   ++ D +TG+S+GYGF+T +D   A +A + 
Sbjct: 1923 KIFVGGLPYHTTDHSLREYFDKFGDIDEAVVITDRQTGKSRGYGFVTMADRTGADRACKD 1744

Query: 311  LN 312
             N
Sbjct: 1743 PN 1738
>01278
          Length = 1082

 Score = 53.9 bits (128), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 46/176 (26%), Positives = 75/176 (42%), Gaps = 19/176 (10%)
 Frame = +2

Query: 158 MQLAARIRPRDLEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEFVDV------------- 204
           MQ       +  EE    +GK+++ ++++ R  +         + D              
Sbjct: 311 MQFVNSSEQKQPEEEDDPLGKLKNQKIVTCRICKGDHWTTKCPYKDTLAPLQEKLTEDQR 490

Query: 205 ----SSVPLAIGLTGQRVLGVPIIVQASQ--AEKNRAAAMANNLQKGSAGPMRLYVGSLH 258
               +  P A    G +  G   +  + +  A K R  +MAN  +K  A  +R  V +L 
Sbjct: 491 KPTDTPAPSAAAGPGPKPAGTKYVPPSMRDGANKGRGESMANQ-RKDEAATIR--VTNLS 661

Query: 259 FNITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECAKKALEQLNGF 314
            +  E  L+ +F PFG I  I L  D  TG+SKG+ FI F   E A +A+  ++GF
Sbjct: 662 EDTRESDLQELFRPFGPISRIYLAKDKVTGQSKGFAFINFHRREDASRAIAGVSGF 829
>28652
          Length = 918

 Score = 52.8 bits (125), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 26/73 (35%), Positives = 47/73 (64%), Gaps = 1/73 (1%)
 Frame = -2

Query: 252 LYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECAKKALEQL 311
           ++ G +  +I ED L  +FE  G I  ++LMMD  +  ++GY F+T++  E A +A++Q 
Sbjct: 725 VFCGKIPRDIFEDELIPLFEDCGTIWDLRLMMDPVSNLNRGYCFVTYTTKEAAAEAVKQH 546

Query: 312 NGFEL-AGRPMKV 323
           +G+E+  G+ +KV
Sbjct: 545 DGYEIRKGKKLKV 507

 Score = 43.9 bits (102), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 24/72 (33%), Positives = 41/72 (56%)
 Frame = -2

Query: 252 LYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECAKKALEQL 311
           LYV +L  ++TED L+  F  +G++E ++ + D        YGF+ + D E A KAL+ L
Sbjct: 194 LYVRNLTGDVTEDDLKEKFGAYGKVERVKKIKD--------YGFVHYEDREDALKALDDL 39

Query: 312 NGFELAGRPMKV 323
           +G ++    + V
Sbjct: 38  HGEKIGNLEIDV 3
>24983
          Length = 433

 Score = 50.8 bits (120), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 22/59 (37%), Positives = 37/59 (62%)
 Frame = -2

Query: 254 VGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECAKKALEQLN 312
           +G L ++ T+  LR  F+ FG I+   ++ D +TG+S+GYGF+T +D   A +A +  N
Sbjct: 303 LGGLPYHTTDHSLREYFDKFGDIDEAVVITDRQTGKSRGYGFVTMADRTGADRACKDPN 127
>20488
          Length = 3281

 Score = 50.8 bits (120), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 28/95 (29%), Positives = 50/95 (52%), Gaps = 2/95 (2%)
 Frame = +2

Query: 239  ANNLQKGSAGP--MRLYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFI 296
            AN+  K S GP    L++  L     +  L  +F PFG + S ++ +D +T  SK +GF+
Sbjct: 2669 ANSAGKHSEGPDGANLFIYHLPQEFGDQDLMQMFMPFGNVVSAKVFIDKQTNLSKCFGFV 2848

Query: 297  TFSDSECAKKALEQLNGFELAGRPMKVGHVTERTD 331
            ++     A+ A+  +NGF++  + +KV     + D
Sbjct: 2849 SYDSPLAAQAAITSMNGFQIGMKRLKVQLKRSKND 2953
>16427
          Length = 1313

 Score = 50.1 bits (118), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 28/91 (30%), Positives = 49/91 (53%)
 Frame = +1

Query: 233 NRAAAMANNLQKGSAGPMRLYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSKG 292
           NR A   ++       P +L+VG L   I E +L   F  FGRI    ++ D     S+G
Sbjct: 85  NRYAVTMSHRTFEKDRPGKLFVGGLAEEIDEKVLEREFSKFGRITESMVIRDKVRQVSRG 264

Query: 293 YGFITFSDSECAKKALEQLNGFELAGRPMKV 323
           +GF+T+ +   A++A++ ++G E+ G+ + V
Sbjct: 265 FGFVTYENPMDAEEAVKHMDGKEILGKKLHV 357
>03744
          Length = 3486

 Score = 49.3 bits (116), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 28/100 (28%), Positives = 50/100 (50%), Gaps = 7/100 (7%)
 Frame = -1

Query: 239  ANNLQKGSAGP-------MRLYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSK 291
            AN+  K S GP         L++  L     +  L  +F PFG + S ++ +D +T  SK
Sbjct: 3270 ANSAGKHSEGPRVPGPDGANLFIYHLPQEFGDQDLMQMFMPFGNVVSAKVFIDKQTNLSK 3091

Query: 292  GYGFITFSDSECAKKALEQLNGFELAGRPMKVGHVTERTD 331
             +GF+++     A+ A+  +NGF++  + +KV     + D
Sbjct: 3090 CFGFVSYDSPLAAQAAITSMNGFQIGMKRLKVQLKRSKND 2971
>00556
          Length = 2189

 Score = 48.9 bits (115), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 22/73 (30%), Positives = 41/73 (56%)
 Frame = +3

Query: 251 RLYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECAKKALEQ 310
           ++++G L   ++ED ++ +   FG ++S  L+ D+ TG SKG+ F  + D     +A   
Sbjct: 762 KIFMGGLPSYLSEDQMKELLLSFGPLKSFNLVRDNATGLSKGFAFCEYLDPSVTDQACAG 941

Query: 311 LNGFELAGRPMKV 323
           LNG +L  + + V
Sbjct: 942 LNGMQLGDKKLIV 980

 Score = 33.5 bits (75), Expect = 0.24,   Method: Compositional matrix adjust.
 Identities = 25/96 (26%), Positives = 42/96 (43%), Gaps = 6/96 (6%)
 Frame = +3

Query: 423  TQCFQLSNMFNPQTEEEVGWDTEIKDDVIEECNKHGGVIHIYVDKN------SAQGNVYV 476
            T+   L NM  P+  E+     +I + V EEC K+G V  + + +          G ++V
Sbjct: 1077 TEILCLMNMIMPEELEDEEEYEDILEXVKEECGKYGSVRSLEIPRPIKGVEVPGVGKIFV 1256

Query: 477  KCPSXXXXXXXVNALHGRWFAGKMITAAYVPLPTYH 512
            +  S         AL GR F+ +++  +Y     YH
Sbjct: 1257 EFNSILDCQKAQQALAGRKFSSRVVVTSYFDPDAYH 1364
>12350
          Length = 975

 Score = 48.9 bits (115), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 25/59 (42%), Positives = 35/59 (59%)
 Frame = -2

Query: 252 LYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECAKKALEQ 310
           L V  L +  TED LR  F  FG +  +Q+  D +TG+SKG+GFI F++ E   K + Q
Sbjct: 614 LIVLGLPWKSTEDDLRSYFSQFGDLLMVQVKKDPKTGQSKGFGFIRFAEYESQLKCMAQ 438

 Score = 37.7 bits (86), Expect = 0.012,   Method: Compositional matrix adjust.
 Identities = 30/140 (21%), Positives = 59/140 (42%), Gaps = 2/140 (1%)
 Frame = -2

Query: 168 DLEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEFVDVSSVPLAIGLTGQRVLGVPIIVQA 227
           DL  +FS  G +  V++  D  + +SKG  ++ F +  S              +  + Q 
Sbjct: 575 DLRSYFSQFGDLLMVQVKKDPKTGQSKGFGFIRFAEYESQ-------------LKCMAQR 435

Query: 228 SQAEKNRAAAMANNLQKGSAGPM--RLYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDS 285
              +         N ++G+   M  +++VG    ++T D LR  F  FG +  + +    
Sbjct: 434 HMIDGRWCDVRIPNSKEGAQQLMNRKIFVGRCTDDMTADDLRQFFSKFGEVVDVFIPRP- 258

Query: 286 ETGRSKGYGFITFSDSECAK 305
                + + F++F+D E A+
Sbjct: 257 ----FRAFAFVSFADPEVAQ 210
>30672
          Length = 877

 Score = 47.4 bits (111), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 41/208 (19%), Positives = 84/208 (40%), Gaps = 34/208 (16%)
 Frame = +3

Query: 150 RDARTVFCMQLAARIRPRDLEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEFV----DVS 205
           R ++T+F   L        L E F  VG ++   +++ +   + +G  YV+F      + 
Sbjct: 3   RQSKTLFVRNLPFETSNEKLLEAFEQVGPLKTAFVVAGKEPGKCRGFGYVQFSMLEDAIK 182

Query: 206 SVPLAIGLTGQRV-LGVPIIVQASQAEKNRAAAMANNLQKGSAGP--------------- 249
           +       +G+++ L      ++ + ++      ++ L  G   P               
Sbjct: 183 AKDTVTHCSGRKISLSFADTKKSWKTKQKGGTETSDALGLGKKLPSQTAVTDGEPNPKPE 362

Query: 250 --------------MRLYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGF 295
                          RL + +L F   E  +R  F  FG I  + + +  +  RS+G+ F
Sbjct: 363 KKKTKQPKQELGKRCRLIIRNLAFKCKEADIRSHFGKFGTISEVTIPL-KQGDRSRGFAF 539

Query: 296 ITFSDSECAKKALEQLNGFELAGRPMKV 323
           + F++ + A+KA+  +NG  +  RP+ V
Sbjct: 540 VQFTEVKAAQKAISDMNGTAIMDRPVAV 623
>14258
          Length = 1063

 Score = 47.0 bits (110), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 19/61 (31%), Positives = 40/61 (65%)
 Frame = +2

Query: 263 EDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECAKKALEQLNGFELAGRPMK 322
           +D+++ +F PFG + S ++ +D +T  SK +GF+++     A+ A+  +NGF++  + +K
Sbjct: 104 QDLMQ-MFMPFGNVISAKVFIDKQTNLSKCFGFVSYDSPMSAQDAISSMNGFQIGMKRLK 280

Query: 323 V 323
           V
Sbjct: 281 V 283
>26197
          Length = 1365

 Score = 47.0 bits (110), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 18/51 (35%), Positives = 32/51 (62%)
 Frame = -2

Query: 251  RLYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDS 301
            +++VG L +  +   LR  FE FG + S  L  D ++G+S+G+GF+ F ++
Sbjct: 1295 KIFVGGLSWETSSKHLREYFEKFGEVTSCTLKTDLDSGKSRGFGFVVFKEA 1143

 Score = 39.3 bits (90), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 19/79 (24%), Positives = 41/79 (51%)
 Frame = -3

Query: 232  KNRAAAMANNLQKGSAGPMRLYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSK 291
            K+  + ++   Q+ + G  R +VG L   + ++ +   F  FG++ +++L  D    + +
Sbjct: 1099 KDVKSTLSQQTQERA*G--RFFVGKLDPGVPQEDVESYFAKFGKVVNVELPYDKVKDQRR 926

Query: 292  GYGFITFSDSECAKKALEQ 310
             + F+ F + +  KK LEQ
Sbjct: 925  AFCFVEFDNDKTVKKVLEQ 869

 Score = 32.3 bits (72), Expect = 0.52,   Method: Compositional matrix adjust.
 Identities = 18/86 (20%), Positives = 39/86 (45%)
 Frame = -3

Query: 156  FCMQLAARIRPRDLEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEFVDVSSVPLAIGLTG 215
            F  +L   +   D+E +F+  GKV +V +  D+   + +   +VEF +  +V   +  T 
Sbjct: 1042 FVGKLDPGVPQEDVESYFAKFGKVVNVELPYDKVKDQRRAFCFVEFDNDKTVKKVLEQTS 863

Query: 216  QRVLGVPIIVQASQAEKNRAAAMANN 241
             ++ G  + +     +    ++M  N
Sbjct: 862  HKIGGQEVRIFKEILKSKEGSSMQEN 785
>13457
          Length = 4857

 Score = 46.6 bits (109), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 23/63 (36%), Positives = 38/63 (60%)
 Frame = -1

Query: 251  RLYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECAKKALEQ 310
            +L+VG L+   TE+ +R +F P+G IE   ++ D + G SKG  F+ +S    A+ A+  
Sbjct: 3405 KLFVGMLNKQQTEEDVRQLFHPYGAIEECTILRD-QNGNSKGCAFVKYSTHSEAQAAINA 3229

Query: 311  LNG 313
            L+G
Sbjct: 3228 LHG 3220

 Score = 30.8 bits (68), Expect = 1.4,   Method: Compositional matrix adjust.
 Identities = 10/31 (32%), Positives = 22/31 (70%)
 Frame = -2

Query: 293  YGFITFSDSECAKKALEQLNGFELAGRPMKV 323
            +GF++F +   A+ A++ +NGF++  + +KV
Sbjct: 2294 FGFVSFDNPASAQAAIQAMNGFQIGMKRLKV 2202
>11019
          Length = 552

 Score = 46.2 bits (108), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 19/47 (40%), Positives = 29/47 (61%)
 Frame = -1

Query: 254 VGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSD 300
           +G L +  T + LR  FE FG I+   +M D  + RS+G+GF+T+ D
Sbjct: 552 IGGLSWQTTTETLRSYFEKFGEIKESMVMKDPTSKRSRGFGFVTYKD 412
>08958
          Length = 680

 Score = 45.8 bits (107), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 25/85 (29%), Positives = 44/85 (51%)
 Frame = +2

Query: 243 QKGSAGPMRLYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSE 302
           +K   G  RL+VG+L  +++ED  + +F PFG +       ++     +G+GFI      
Sbjct: 47  RKKFTGRCRLFVGNLTPDVSEDDFKKLFSPFGEVS------EAYVNSGRGFGFIRLDYRH 208

Query: 303 CAKKALEQLNGFELAGRPMKVGHVT 327
            A+ A   L+G +  GR ++V + T
Sbjct: 209 NAEAAKAALDGLQRKGRSLRVRYAT 283
>23720
          Length = 739

 Score = 45.4 bits (106), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 24/76 (31%), Positives = 36/76 (47%)
 Frame = -1

Query: 251 RLYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECAKKALEQ 310
           R+Y+G L +   E  +   F  +GR+  I L          GYGF+ F D   A  A+ +
Sbjct: 682 RVYIGRLPYQAREKDIERFFRGYGRVNDIML--------KNGYGFVEFEDFRDADDAVYE 527

Query: 311 LNGFELAGRPMKVGHV 326
           LNG +L G  + + H 
Sbjct: 526 LNGKDLCGERVIIEHA 479
>04988
          Length = 705

 Score = 45.4 bits (106), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 24/75 (32%), Positives = 36/75 (48%)
 Frame = -3

Query: 251 RLYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECAKKALEQ 310
           R+Y+G L +   E  +   F  +GR+  I L          GYGF+ F D   A  A+ +
Sbjct: 649 RVYIGRLPYQAREKDIERFFRGYGRVNDIML--------KNGYGFVEFEDFRDADDAVYE 494

Query: 311 LNGFELAGRPMKVGH 325
           LNG +L G  + + H
Sbjct: 493 LNGKDLCGERVIIEH 449
>03903
          Length = 983

 Score = 45.4 bits (106), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 28/81 (34%), Positives = 41/81 (50%), Gaps = 8/81 (9%)
 Frame = -1

Query: 251 RLYVGSLHFNITEDMLRGIF--------EPFGRIESIQLMMDSETGRSKGYGFITFSDSE 302
           RLY+ +L   +TE+ L  +F        E    I  I+LM +   GR KG  F+T    E
Sbjct: 455 RLYIKNLSKQVTEEDLHWVFGRYVNWDKEEEKSIFDIRLMKE---GRMKGQAFVTLGTEE 285

Query: 303 CAKKALEQLNGFELAGRPMKV 323
            A+KA++  N F   G+P+ V
Sbjct: 284 QARKAVKDTNAFVFKGKPIAV 222
>14637
          Length = 455

 Score = 44.7 bits (104), Expect = 9e-05,   Method: Compositional matrix adjust.
 Identities = 28/91 (30%), Positives = 47/91 (51%), Gaps = 2/91 (2%)
 Frame = -1

Query: 228 SQAEKNRAAAMANNLQKGSAGP--MRLYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDS 285
           +Q ++N AA       K S GP    L++  L     +  L  +F PFG + S ++ +D 
Sbjct: 254 NQMQQNAAA-------KQSEGPDGSNLFIYHLPQEFGDQDLMQMFMPFGNVISAKVFIDK 96

Query: 286 ETGRSKGYGFITFSDSECAKKALEQLNGFEL 316
           +T  SK +GF+++     A+ A+  +NGF L
Sbjct: 95  QTNLSKCFGFVSYDSPMSAQDAISSMNGFRL 3
>02343
          Length = 1715

 Score = 44.7 bits (104), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 21/62 (33%), Positives = 34/62 (54%)
 Frame = -2

Query: 252  LYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECAKKALEQL 311
            LY+  L  N T+  L  + + FG I S + ++D  T + KGYGF+ F     A++A++ L
Sbjct: 1258 LYIRGLSPNTTDKDLVNLCQHFGTITSTKAIIDQTTNKCKGYGFVDFDAPGAAERAVQAL 1079

Query: 312  NG 313
              
Sbjct: 1078 QA 1073

 Score = 43.1 bits (100), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 37/159 (23%), Positives = 65/159 (40%)
 Frame = -2

Query: 160  LAARIRPRDLEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEFVDVSSVPLAIGLTGQRVL 219
            L+     +DL       G +   + I D+ + + KG  +V+F      P A     +R  
Sbjct: 1243 LSPNTTDKDLVNLCQHFGTITSTKAIIDQTTNKCKGYGFVDF----DAPGA----AERA- 1091

Query: 220  GVPIIVQASQAEKNRAAAMANNLQKGSAGPMRLYVGSLHFNITEDMLRGIFEPFGRIESI 279
                 VQA QA+  +A       Q     P  LY+ +L  + TE  L G+F+ +G + S 
Sbjct: 1090 -----VQALQAQGIQAQMAKQQEQD----PTNLYIANLPLHFTEKHLEGLFKDYGTVIST 938

Query: 280  QLMMDSETGRSKGYGFITFSDSECAKKALEQLNGFELAG 318
            +++   + G S+  GF      +     +   N   ++G
Sbjct: 937  RILRKPD-GISRCVGFARMESRDKCDTVINTFNNKMISG 824
>15503
          Length = 570

 Score = 43.5 bits (101), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 33/115 (28%), Positives = 53/115 (46%), Gaps = 9/115 (7%)
 Frame = +1

Query: 218 VLGVPI-----IVQASQAEKNRAAAMANNLQKGSAGPMR----LYVGSLHFNITEDMLRG 268
           +L +PI     I+  S    N+   MA + +     P      LYV +L + IT + +  
Sbjct: 25  LLSIPIQFSNRIILVSPLPHNKNFKMAMSKKGNVRLPPEVNRVLYVKNLPYKITAEEMYD 204

Query: 269 IFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECAKKALEQLNGFELAGRPMKV 323
           IF  +G I  I++     T  +KG  F+ + D   AK A + L+GF +  R + V
Sbjct: 205 IFGKYGAIRQIRV---GNTPETKGTAFVVYEDIFDAKNACDHLSGFNVCNRYLVV 360
>21096
          Length = 1186

 Score = 43.5 bits (101), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 26/73 (35%), Positives = 44/73 (60%)
 Frame = +3

Query: 251 RLYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECAKKALEQ 310
           RL+V     ++ E +LR  F  FG + S+ L+    +GR+  YG+  +++ E A KAL+ 
Sbjct: 75  RLFVVCQPGSVPERVLRDAFSRFGNLISVYLL----SGRN--YGYAKYANHESAMKALQT 236

Query: 311 LNGFELAGRPMKV 323
           L+G  L+G+ +KV
Sbjct: 237 LHGQSLSGQRLKV 275
>32733
          Length = 709

 Score = 43.1 bits (100), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 21/62 (33%), Positives = 37/62 (59%)
 Frame = +1

Query: 251 RLYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECAKKALEQ 310
           R   G L   ++E+ +R +FE FG I+   ++ DS  G S+G  FITF+  +CA  +++ 
Sbjct: 469 RCLWGMLSKKLSENDVRMLFESFGSIDDCTVLRDSN-GTSRGCAFITFASRQCAMNSIKG 645

Query: 311 LN 312
           ++
Sbjct: 646 MH 651
>25691
          Length = 768

 Score = 42.7 bits (99), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 19/46 (41%), Positives = 28/46 (60%)
 Frame = -2

Query: 278 SIQLMMDSETGRSKGYGFITFSDSECAKKALEQLNGFELAGRPMKV 323
           + +L+ D  TG+S GYGF+ +   E A KA+  LNG  L  + +KV
Sbjct: 434 TCKLIRDKPTGQSLGYGFVNYKRQEDADKAIHTLNGLRLQNKTIKV 297

 Score = 42.0 bits (97), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 22/61 (36%), Positives = 36/61 (59%)
 Frame = -2

Query: 252 LYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECAKKALEQL 311
           LY+  L  ++T+  L  +F   G I + +++ D  TG SKG GFI F     A++A+++L
Sbjct: 254 LYISGLPKSLTQLDLENLFTDCGNIITSRILYDQTTGLSKGVGFIRFDQRIEAERAIQKL 75

Query: 312 N 312
           N
Sbjct: 74  N 72

 Score = 30.4 bits (67), Expect = 2.0,   Method: Compositional matrix adjust.
 Identities = 11/34 (32%), Positives = 20/34 (58%)
 Frame = -2

Query: 168 DLEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEF 201
           DLE  F+  G +   R++ D+ +  SKG+ ++ F
Sbjct: 215 DLENLFTDCGNIITSRILYDQTTGLSKGVGFIRF 114
>03200
          Length = 657

 Score = 42.4 bits (98), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 21/63 (33%), Positives = 34/63 (53%)
 Frame = -1

Query: 261 ITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECAKKALEQLNGFELAGRP 320
           +TED+L+  F  FG I +I +       R +  GF+TF   E A +A+  +NG  ++   
Sbjct: 459 VTEDILKSAFSNFGNIVNINI------ERERNNGFVTFEKMESADQAIANMNGSMISNVQ 298

Query: 321 MKV 323
           +KV
Sbjct: 297 LKV 289
>05273
          Length = 1009

 Score = 42.0 bits (97), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 17/39 (43%), Positives = 27/39 (69%)
 Frame = -1

Query: 262 TEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSD 300
           T+  LR  F+ FG I+   ++ D +TG+S+GYGF+T +D
Sbjct: 163 TDHSLREYFDKFGDIDEAVVITDRQTGKSRGYGFVTMAD 47
>23655
          Length = 929

 Score = 39.7 bits (91), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 15/43 (34%), Positives = 27/43 (62%)
 Frame = -1

Query: 251 RLYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSKGY 293
           +++VG +  + TEDM+R  F  FG I  + L+ D  TG+++ +
Sbjct: 902 KMFVGGVKEDTTEDMIRDTFNEFGEITGVDLIQDKGTGKNRDF 774
>23250
          Length = 1617

 Score = 39.3 bits (90), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 17/54 (31%), Positives = 29/54 (53%)
 Frame = -1

Query: 252  LYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECAK 305
            +Y+G +     E  ++  F  FGR+  ++L   ++TG SKGY F+ F    C +
Sbjct: 1329 VYLGHIPAGFYEPQMKRFFSQFGRVTRLRLSRSTKTGGSKGYAFLEF*TRGCGQ 1168

 Score = 28.9 bits (63), Expect = 5.9,   Method: Compositional matrix adjust.
 Identities = 15/51 (29%), Positives = 25/51 (49%)
 Frame = -1

Query: 151  DARTVFCMQLAARIRPRDLEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEF 201
            D   V+   + A      ++ FFS  G+V  +R+     +  SKG A++EF
Sbjct: 1341 DRGVVYLGHIPAGFYEPQMKRFFSQFGRVTRLRLSRSTKTGGSKGYAFLEF 1189
>25950
          Length = 417

 Score = 38.5 bits (88), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 23/80 (28%), Positives = 41/80 (51%)
 Frame = -2

Query: 252 LYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECAKKALEQL 311
           +YVG++ +  + + L   F   G I  + ++ +   G  KG+ +I F   E  + AL  +
Sbjct: 275 VYVGNVDYGASAEELEAHFHGCGTINRVTILCNKADGHPKGFAYIEFGSKEYVETAL-AM 99

Query: 312 NGFELAGRPMKVGHVTERTD 331
           N     GR +KV  +T+RT+
Sbjct: 98  NETLFRGRQIKV--MTKRTN 45
>00029
          Length = 2204

 Score = 38.1 bits (87), Expect = 0.009,   Method: Compositional matrix adjust.
 Identities = 21/87 (24%), Positives = 43/87 (49%)
 Frame = -3

Query: 237  AMANNLQKGSAGPMRLYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFI 296
            A+ NN +      +++++G+L  +   + LR +FE +G +    ++        K +GF+
Sbjct: 2169 ALENNTKYNMT--IKIFIGNLGDDTDPEELRALFEKYGSVAECDVL--------KNFGFV 2020

Query: 297  TFSDSECAKKALEQLNGFELAGRPMKV 323
                   A  A+  LNG+ + G+ M+V
Sbjct: 2019 HMVKKGEADDAISNLNGYNIGGQRMRV 1939
>29364
          Length = 1126

 Score = 37.7 bits (86), Expect = 0.011,   Method: Compositional matrix adjust.
 Identities = 21/68 (30%), Positives = 34/68 (50%), Gaps = 1/68 (1%)
 Frame = +1

Query: 164 IRPRDLEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEFVDVSSVPLAI-GLTGQRVLGVP 222
           +R RDLE FF   G+ RD+ +          G  +VEF D      A+  L G+ +LG  
Sbjct: 1   VRERDLERFFKGYGRTRDILI--------KNGYGFVEFEDYRDADDAVYELNGKELLGER 156

Query: 223 IIVQASQA 230
           ++V+ ++ 
Sbjct: 157 VVVEPARG 180

 Score = 34.3 bits (77), Expect = 0.13,   Method: Compositional matrix adjust.
 Identities = 20/58 (34%), Positives = 27/58 (46%)
 Frame = +1

Query: 261 ITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECAKKALEQLNGFELAG 318
           + E  L   F+ +GR   I +          GYGF+ F D   A  A+ +LNG EL G
Sbjct: 1   VRERDLERFFKGYGRTRDILI--------KNGYGFVEFEDYRDADDAVYELNGKELLG 150
>28455
          Length = 573

 Score = 37.7 bits (86), Expect = 0.013,   Method: Compositional matrix adjust.
 Identities = 21/47 (44%), Positives = 27/47 (57%)
 Frame = -1

Query: 155 VFCMQLAARIRPRDLEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEF 201
           +F   L        LE  F   GKV+DVR+++ R S  SKG+AYVEF
Sbjct: 534 LFVKNLPFTCSAEALETIFKEHGKVKDVRLVTYR-SGASKGLAYVEF 397
>11126
          Length = 1061

 Score = 36.6 bits (83), Expect = 0.024,   Method: Compositional matrix adjust.
 Identities = 19/74 (25%), Positives = 37/74 (50%), Gaps = 2/74 (2%)
 Frame = -3

Query: 252 LYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECAKKALEQL 311
           +YVG++ +  T + L   F   G +  + ++ D  +G  KG+ ++ F+D +    A  + 
Sbjct: 624 VYVGNVDYGATAEELEQHFHGCGSVNRVTILCDKYSGHPKGFAYVEFADKDSVVTA--KC 451

Query: 312 NGFE--LAGRPMKV 323
            G +    GR +KV
Sbjct: 450 TGMDSLFRGRQIKV 409
>15371
          Length = 383

 Score = 36.6 bits (83), Expect = 0.026,   Method: Composition-based stats.
 Identities = 20/62 (32%), Positives = 34/62 (54%), Gaps = 2/62 (3%)
 Frame = -2

Query: 239 ANNLQKGSAGP--MRLYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFI 296
           AN+  K S GP    L++  L     +  L  +F PFG + S ++ +D +T  SK +GF+
Sbjct: 196 ANSAGKHSEGPDGANLFIYHLPQEFGDQDLMQMFMPFGNVVSAKVFIDKQTNLSKCFGFV 17

Query: 297 TF 298
           ++
Sbjct: 16  SY 11
>11108
          Length = 493

 Score = 35.8 bits (81), Expect = 0.047,   Method: Composition-based stats.
 Identities = 22/84 (26%), Positives = 42/84 (50%), Gaps = 12/84 (14%)
 Frame = -1

Query: 251 RLYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSD--------SE 302
           ++++G + ++I+E  L  IF+PFG I+      + +  + KGY +I F          S 
Sbjct: 289 KVFLGGIPWDISEQSLIQIFKPFGSIKVEWPGKEQQAAQPKGYVYIIFESDKQVKALLSA 110

Query: 303 CAKKALEQLNG----FELAGRPMK 322
           C  +  +  NG    F+++ R +K
Sbjct: 109 CVLQVDDSQNGSNYFFKISSRRIK 38
>00741
          Length = 1846

 Score = 34.7 bits (78), Expect = 0.093,   Method: Compositional matrix adjust.
 Identities = 19/60 (31%), Positives = 33/60 (55%), Gaps = 8/60 (13%)
 Frame = -3

Query: 452  EECNKHGGV--IHIYVDKNSAQGN------VYVKCPSXXXXXXXVNALHGRWFAGKMITA 503
            +EC K G V  + IY +K S + N      ++V+          V++L+GR+F G+++TA
Sbjct: 1523 DECEKFGAVKRVIIYQEKQSEEENAEIIVKIFVEFSKQEELEKAVSSLNGRFFGGRVLTA 1344
>16016
          Length = 1364

 Score = 34.7 bits (78), Expect = 0.094,   Method: Compositional matrix adjust.
 Identities = 30/132 (22%), Positives = 55/132 (41%)
 Frame = -2

Query: 139  REPIDNLTPEERDARTVFCMQLAARIRPRDLEEFFSTVGKVRDVRMISDRNSRRSKGIAY 198
            R  +D+    ER+ R VF   +        L  +F   G +R+  ++ D  ++RS+  ++
Sbjct: 1348 RSNLDDNPNAERN-RKVFIGGMHPDTDESSLRSYFEKYGDIRECIVVKDPATKRSRCFSF 1172

Query: 199  VEFVDVSSVPLAIGLTGQRVLGVPIIVQASQAEKNRAAAMANNLQKGSAGPMRLYVGSLH 258
            + F +  +V        +     P  +     E  RA  M     +      +++VG L 
Sbjct: 1171 ITFGNAENV-------DEVQKDRPHTIDGRTVETKRA--MPREDTENHHQTKKMFVGGLK 1019

Query: 259  FNITEDMLRGIF 270
             + TE+MLR  F
Sbjct: 1018 DDTTEEMLRKEF 983
>03097
          Length = 1401

 Score = 34.7 bits (78), Expect = 0.098,   Method: Compositional matrix adjust.
 Identities = 23/86 (26%), Positives = 38/86 (44%), Gaps = 3/86 (3%)
 Frame = +1

Query: 429 SNMFNPQTEEEVGWDTEIKDDVIEECNKHGGVIHIYVDKNSAQ---GNVYVKCPSXXXXX 485
           S++ +   E +  +D   ++  IE   K+G +  + +  N      GNVYVK        
Sbjct: 103 SHIMSNDVEAQQEFDDFFEEIFIELAEKYGEIEEMNICDNLGDHLVGNVYVKFRKEEDAD 282

Query: 486 XXVNALHGRWFAGKMITAAYVPLPTY 511
             V  L+ RWF G+ I A   P+  +
Sbjct: 283 KAVADLNNRWFNGRPIYAELTPVTDF 360
>09736
          Length = 1319

 Score = 34.3 bits (77), Expect = 0.12,   Method: Compositional matrix adjust.
 Identities = 17/50 (34%), Positives = 33/50 (66%), Gaps = 1/50 (2%)
 Frame = -2

Query: 276  IESIQLMMDSETGRSKGYGFITFSDSECAKKALEQLNGFELAG-RPMKVG 324
            +   ++++D+ +G+SKG+GF+ FS+    ++AL ++      G RP+KVG
Sbjct: 1309 VRGAKVVLDA-SGKSKGFGFVRFSEENDQQRALVEMQHMTGIGRRPIKVG 1163
>16936
          Length = 243

 Score = 32.7 bits (73), Expect = 0.40,   Method: Composition-based stats.
 Identities = 15/25 (60%), Positives = 18/25 (72%)
 Frame = -2

Query: 504 AYVPLPTYHNLFPDSMTATQLLVPS 528
           AYVPLP Y  LF +S+ ATQ L+ S
Sbjct: 242 AYVPLPNYATLFVESVRATQPLMTS 168
>28372
          Length = 398

 Score = 32.3 bits (72), Expect = 0.53,   Method: Compositional matrix adjust.
 Identities = 13/33 (39%), Positives = 25/33 (75%)
 Frame = -2

Query: 291 KGYGFITFSDSECAKKALEQLNGFELAGRPMKV 323
           +G+GF+TF+ S  A++A +++NG  + GR ++V
Sbjct: 259 QGFGFVTFAHSAEAERARDKMNGTVVEGRKIEV 161
>19733
          Length = 723

 Score = 31.6 bits (70), Expect = 0.84,   Method: Compositional matrix adjust.
 Identities = 27/85 (31%), Positives = 41/85 (48%), Gaps = 14/85 (16%)
 Frame = +3

Query: 251 RLYVGSLHFNITEDMLRGIFEPF-----GRIESIQLMMD----SETGRSK--GYGFITFS 299
           RL V +L  ++ E  L+ +          +I   ++M D     ++G+SK  GY F+ FS
Sbjct: 393 RLCVHNLLPSVDEKQLKTVVRKIVDDSTMKITECRVMRDLARTKQSGQSKSLGYAFVNFS 572

Query: 300 DSECAKKALEQLNGFELAG---RPM 321
             E A KAL  LN   + G   RP+
Sbjct: 573 THEHALKALRGLNNSTMFGDSRRPI 647
>28605
          Length = 697

 Score = 31.2 bits (69), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 20/75 (26%), Positives = 40/75 (53%), Gaps = 1/75 (1%)
 Frame = -3

Query: 251 RLYVGSLHFNIT-EDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECAKKALE 309
           R++V +L  + T E  L+ +F  +G +      +D+    ++ YGF+ FS  E  ++A+E
Sbjct: 566 RVFVANLSSDETSEAELQELFSKYGNV------LDTLVHHNR-YGFVQFSTEEEGRRAVE 408

Query: 310 QLNGFELAGRPMKVG 324
            +NG+    + +K  
Sbjct: 407 AMNGYMFYRKKLKCN 363
>25632
          Length = 864

 Score = 29.3 bits (64), Expect = 3.7,   Method: Compositional matrix adjust.
 Identities = 15/55 (27%), Positives = 25/55 (45%)
 Frame = -2

Query: 269 IFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECAKKALEQLNGFELAGRPMKV 323
             E +G +E   ++        K YGF+       A  A+  LNG+ + G+ M+V
Sbjct: 710 CLEKYGTVEECDVL--------KNYGFVHMPTKSEASAAITNLNGYNIKGQRMRV 570
>32980
          Length = 651

 Score = 29.3 bits (64), Expect = 4.6,   Method: Compositional matrix adjust.
 Identities = 11/16 (68%), Positives = 15/16 (93%)
 Frame = +3

Query: 188 RNSRRSKGIAYVEFVD 203
           RNSRR+KG +YV++VD
Sbjct: 207 RNSRRNKGESYVQYVD 254
>35180
          Length = 2181

 Score = 28.1 bits (61), Expect = 8.3,   Method: Compositional matrix adjust.
 Identities = 20/75 (26%), Positives = 34/75 (45%), Gaps = 3/75 (4%)
 Frame = -2

Query: 141 PIDNLTPEERD---ARTVFCMQLAARIRPRDLEEFFSTVGKVRDVRMISDRNSRRSKGIA 197
           P+ + T E +D   +R+V+       I    L EFF   GK+  + M  +R  +  KG  
Sbjct: 305 PLPDNTKERKDDINSRSVYVKGFPEDITLDTLMEFFEQHGKIDTILMRRNRPDKNFKGSV 126

Query: 198 YVEFVDVSSVPLAIG 212
           +V F +     + +G
Sbjct: 125 FVTFSNKEEEDVFLG 81
>02140
          Length = 1796

 Score = 28.1 bits (61), Expect = 9.0,   Method: Compositional matrix adjust.
 Identities = 15/47 (31%), Positives = 22/47 (46%)
 Frame = +3

Query: 155 VFCMQLAARIRPRDLEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEF 201
           +F  +L       DLE  FS  G +    +I D  ++ S   A+VEF
Sbjct: 807 LFVCKLNPVTTDEDLEMIFSRFGPITSCEVIRDHKTKESLQYAFVEF 947
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|86439977|ref|NP_056569.2| retinoblastoma binding
protein 9 [Mus musculus]
         (186 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

29515                                                                 178   9e-46
00846                                                                  31   0.23 
06078                                                                  28   1.9  
>29515
          Length = 580

 Score =  178 bits (452), Expect = 9e-46,   Method: Compositional matrix adjust.
 Identities = 84/164 (51%), Positives = 109/164 (66%)
 Frame = +1

Query: 20  THGWYGWVKKGLEQIPGFQCLAKNMPDPITARESIWLPFMETELHCDEKTXXXXXXXXXX 79
           TH    W+ + L +  G +C+ +N PDPI ARES+W+PFM  EL CD  T          
Sbjct: 79  THLST*WLAEELTK-AGVKCILRNFPDPIKARESVWIPFMRDELSCDHTTIIVGHSSGAE 255

Query: 80  XXMRYAETHQVYALVLVSAYTSDLGDENERASGYFSRPWQWEKIKANCPHIVQFGSTDDP 139
             MRYAETH+V  +VLVSA  +DLG+E+ER SGY++RPW W+ ++ N     QFGSTDDP
Sbjct: 256 AAMRYAETHKVKGIVLVSACVTDLGEESERVSGYYNRPWXWQDMQNNTDFAAQFGSTDDP 435

Query: 140 FLPWKEQQEVADRLDAKLYKFTDRGHFQNTEFHELISVVKSMLK 183
           F+ W EQQ+VAD L  KL+KF DRGHF NT F EL+S + ++ K
Sbjct: 436 FIAWSEQQQVADGLGTKLFKFDDRGHFMNTVFPELLSFLMTVCK 567
>00846
          Length = 4234

 Score = 31.2 bits (69), Expect = 0.23,   Method: Compositional matrix adjust.
 Identities = 16/46 (34%), Positives = 20/46 (43%)
 Frame = +1

Query: 12   GNGGGDVATHGWYGWVKKGLEQIPGFQCLAKNMPDPITARESIWLP 57
             NG   +AT G Y    KGL Q     C +   P PI++    W P
Sbjct: 1765 SNGNISLATMGSYREFAKGLSQTSRPNCRSSVAPSPISSPAGRW*P 1902
>06078
          Length = 1315

 Score = 28.1 bits (61), Expect = 1.9,   Method: Compositional matrix adjust.
 Identities = 18/45 (40%), Positives = 25/45 (55%), Gaps = 4/45 (8%)
 Frame = +1

Query: 92  ALVLVSAYTSDLGDENERASGYFSR----PWQWEKIKANCPHIVQ 132
           A V VSA  SD G EN+ A  + +R    P  W+++K  C  I+Q
Sbjct: 634 ADVKVSAEDSDSGSENDSAMCFSARTFWTPENWKEVKK-CSSILQ 765
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|41322904|ref|NP_035247.1| plectin 1 isoform 1 [Mus
musculus]
         (4572 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

19002                                                                 184   1e-45
19147                                                                 108   4e-24
29446                                                                  98   9e-20
17613                                                                  70   1e-12
09711                                                                  57   1e-07
05733                                                                  57   2e-07
23752                                                                  53   3e-06
32088                                                                  51   1e-05
09100                                                                  44   0.002
04951                                                                  44   0.002
18202                                                                  43   0.003
32371                                                                  27   0.63 
08049                                                                  34   1.4  
02896                                                                  32   7.2  
>19002
          Length = 842

 Score =  184 bits (466), Expect = 1e-45,   Method: Compositional matrix adjust.
 Identities = 111/276 (40%), Positives = 153/276 (55%), Gaps = 11/276 (3%)
 Frame = -2

Query: 101 DGHNLISLLEV-LSGDSLPREKGRMRFHKLQNVQIALDYLRHRQVKLVNIRNDDIADGNP 159
           DG  L+ LLEV + G+     KG+MR H L+NV  AL +L  ++V L N+   DI DG+ 
Sbjct: 841 DGKMLMKLLEVRVRGEIASDXKGKMRIHCLENVDKALTFLHEQRVHLENMGAHDIVDGSS 662

Query: 160 KLTLGLIWTIILHFQISDIQVS--GQSEDMTAKEKLLLWSQRMVEGYQGLRCDNFTTSWR 217
           +LTLGLIWTIIL FQI DI +     SE  +AK+ LLLW Q    GY  +   NFTTSWR
Sbjct: 661 RLTLGLIWTIILRFQIQDIMIEEVDNSETKSAKDALLLWCQMKTAGYPNVNVRNFTTSWR 482

Query: 218 DGRLFNAIIHRHKPMLIDMNKVYRQTNLENLDQAFSVAERDLGVTRLLXXXXXXXXXXXX 277
           DG  FNAIIH+H+P L+  +++++ + ++NL  AF+VAE  LG+T LL            
Sbjct: 481 DGLAFNAIIHKHRPDLVQYDRLHKSSAIQNLQNAFTVAEDKLGLTALLEPEDVNVEYPDE 302

Query: 278 KSIITYVSSLYDAMPR-----VPGAQDG-VRANELQLR--WQEYRELVLLLLQWIRHHTA 329
           KSIITYV + Y    +     V G + G V  N +      +EY  L   LL+WI     
Sbjct: 301 KSIITYVVTYYHYFSKMKADSVQGKRIGKVIDNAINTENSIEEYETLTSDLLEWIEQTIV 122

Query: 330 AFEERKFPSSFEEIEILWCQFLKFKETELPAKEADK 365
              +R+F +S   ++     F  ++  E P K  +K
Sbjct: 121 ILRDRQFANSLTGVQQQLAAFNTYRIVEKPPKFDEK 14
>19147
          Length = 474

 Score =  108 bits (271), Expect(2) = 4e-24,   Method: Composition-based stats.
 Identities = 55/116 (47%), Positives = 75/116 (64%)
 Frame = +1

Query: 138 YLRHRQVKLVNIRNDDIADGNPKLTLGLIWTIILHFQISDIQVSGQSEDMTAKEKLLLWS 197
           Y+  + VKLV+I  ++I DGN K+TLG+IWTIIL F I DI V    E++TAKE LLLW 
Sbjct: 49  YIASKGVKLVSIGAEEIVDGNVKMTLGMIWTIILRFAIQDITV----EELTAKEGLLLWC 216

Query: 198 QRMVEGYQGLRCDNFTTSWRDGRLFNAIIHRHKPMLIDMNKVYRQTNLENLDQAFS 253
           QR    Y+ +   NF  S++DG  F A+IHRH+P LID + + + + L  + Q  S
Sbjct: 217 QRKTAPYKNVNVQNFHLSFKDGLAFCALIHRHRPELIDYHSLSKVSLLNTVVQTLS 384

 Score = 23.9 bits (50), Expect(2) = 4e-24,   Method: Composition-based stats.
 Identities = 10/18 (55%), Positives = 13/18 (72%)
 Frame = +3

Query: 123 RMRFHKLQNVQIALDYLR 140
           +MRFHK+ NV  AL+  R
Sbjct: 3   KMRFHKIANVNKALELHR 56
>29446
          Length = 1445

 Score = 97.8 bits (242), Expect = 9e-20,   Method: Compositional matrix adjust.
 Identities = 57/138 (41%), Positives = 78/138 (56%), Gaps = 8/138 (5%)
 Frame = +3

Query: 72   VQKKTFTKWVNKHLIKAQRHISDLYEDLRDGHNLISLLEVLSGDSLPREKGRMRF--HKL 129
            +QK TFT+W N+HL    + I+DL  D  DG  L++L+EVLSG        R  F   KL
Sbjct: 999  IQKNTFTRWANEHLRTVNKAIADLESDFSDGLRLVALIEVLSGKKFKHVNKRPNFRTQKL 1178

Query: 130  QNVQIALDYLRHRQ-VKLVNIRNDDIADGNPKLTLGLIWTIILHFQISDIQVSGQSE--- 185
            +NV + L +L   + +++VNI + DI D   KL LGLIWT+ILH+ IS     G+     
Sbjct: 1179 ENVTLTLKFLEDDEGIRIVNIDSTDIVDKKLKLILGLIWTLILHYSISMPMWEGEEPTPS 1358

Query: 186  --DMTAKEKLLLWSQRMV 201
                T K++LL W Q  V
Sbjct: 1359 EGGPTPKQRLLNWIQSKV 1412
>17613
          Length = 1108

 Score = 61.2 bits (147), Expect(3) = 1e-12,   Method: Composition-based stats.
 Identities = 44/145 (30%), Positives = 64/145 (44%), Gaps = 12/145 (8%)
 Frame = +1

Query: 124 MRFHKLQNVQIALDYLR--------HRQVKLV-NIRNDDIA---DGNPKLTLGLIWTIIL 171
           MRFHK+ NV  ALDY+         HR  +     R DDI    D  P++          
Sbjct: 4   MRFHKIANVNKALDYIDLQRGQTGLHRSRRNC*RQRKDDIRYDLDNYPQVC--------- 156

Query: 172 HFQISDIQVSGQSEDMTAKEKLLLWSQRMVEGYQGLRCDNFTTSWRDGRLFNAIIHRHKP 231
                       S     + + ++        Y+ +   NF  S++DG  F A+IHRH+P
Sbjct: 157 -------HPRHHSRRTHCQRRTVIVVPAKTAPYKNVNVQNFHLSFKDGLAFCALIHRHRP 315

Query: 232 MLIDMNKVYRQTNLENLDQAFSVAE 256
            LID + + +   LENL+ AF +AE
Sbjct: 316 ELIDYHSLSKDNPLENLNTAFDIAE 390

 Score = 26.6 bits (57), Expect(3) = 1e-12,   Method: Compositional matrix adjust.
 Identities = 23/70 (32%), Positives = 29/70 (41%), Gaps = 13/70 (18%)
 Frame = +3

Query: 278 KSIITYVSSLYDAMPRVPGAQDGVRA-------------NELQLRWQEYRELVLLLLQWI 324
           +S++ YVSS Y A     GAQ    A             NE  +  +EY  L   LL+WI
Sbjct: 456 RSVMAYVSSYYHAFS---GAQQAETAANRICKVLKVNQENERLM--EEYERLASDLLEWI 620

Query: 325 RHHTAAFEER 334
           R      E R
Sbjct: 621 RRTRPWLENR 650

 Score = 25.4 bits (54), Expect(3) = 1e-12,   Method: Compositional matrix adjust.
 Identities = 29/101 (28%), Positives = 45/101 (44%), Gaps = 6/101 (5%)
 Frame = +2

Query: 356 TELPAKEADKNRSKVIYQSLEGAVQAGQLKIPPGYHPL------DVEKEWGKLHVAILER 409
           TE P  E DK + +  + +L+  ++   L   P Y P       D+   W  L  A    
Sbjct: 716 TEAPKLE-DKAKLENSFNTLQTRLR---LSNRPAYLPTEGKMVSDIANAWKGLEHAEKGF 883

Query: 410 EKQLRSEFERLECLQRIVSKLQMEAGLCEEQLNQADALLQS 450
           E+ L SE +RLE L  +  K + +  + EE     + +LQS
Sbjct: 884 EEWLLSELQRLERLDHLAQKFRHKCEIHEEWSQGKEDMLQS 1006

 Score = 69.7 bits (169), Expect = 3e-11,   Method: Composition-based stats.
 Identities = 35/58 (60%), Positives = 43/58 (74%)
 Frame = +2

Query: 142 RQVKLVNIRNDDIADGNPKLTLGLIWTIILHFQISDIQVSGQSEDMTAKEKLLLWSQR 199
           + VKLV+I  ++I DGN K+TLG+IWTIIL F I DI V    E++TAKE LLLW QR
Sbjct: 59  KGVKLVSIGAEEIVDGNVKMTLGMIWTIILRFAIQDITV----EELTAKEGLLLWCQR 220
>09711
          Length = 3041

 Score = 57.4 bits (137), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 47/201 (23%), Positives = 92/201 (45%), Gaps = 16/201 (7%)
 Frame = +1

Query: 55  LDPAERAVIRIADERDRVQKKTFTKWVNKHLIKAQRHISDLYEDLRDGHNLISLLEVL-- 112
           LD  +  V  +  E  R ++KT+  W+N   +     +  LY DL DG  +  L + +  
Sbjct: 799 LDTPQVEVEDVMKEESR-EEKTYRNWMNS--LGVSPFVHHLYSDLYDGLIIFQLYDYIQP 969

Query: 113 -----SGDSLPREKGRMRFHKLQNVQIALDY---LRHRQVKLVNIRNDDIADGNPKLTLG 164
                S       K + RF +++N   A++    ++  +VKLV I   DI DGNP LTLG
Sbjct: 970 GLVDWSKVKKKFNKLKARFERIENCNYAVELGPQVKLVKVKLVGIAGQDILDGNPVLTLG 1149

Query: 165 LIWTIILHFQISDIQVSGQSEDMTAKEKLLLWSQRMVE------GYQGLRCDNFTTSWRD 218
           L+W ++  + ++ +    ++    +  +++ W    ++      G+Q  + +       D
Sbjct: 1150LVWQLMRAYTLAILSKITENNKPISDNEIITWVNSKIKKDDRISGFQDRKLN-------D 1308

Query: 219 GRLFNAIIHRHKPMLIDMNKV 239
           G +   +I   KP +++ + +
Sbjct: 1309GVIVARVIEAIKPGIVNWDNI 1371

 Score = 43.5 bits (101), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 31/122 (25%), Positives = 60/122 (49%), Gaps = 13/122 (10%)
 Frame = +1

Query: 73  QKKTFTKWVNKHLIKAQ--RHI-------SDLYEDLRDGHNLISLLEVLSGDSLP----R 119
           ++K F +W+N+HL      +H+       + L+  + DG  L  L+     +++      
Sbjct: 52  EQKAFAEWINRHLSDXPDCKHLLPLDADGTQLFGQMADGVLLCKLINHSVSNTIDERTIN 231

Query: 120 EKGRMRFHKLQNVQIALDYLRHRQVKLVNIRNDDIADGNPKLTLGLIWTIILHFQISDIQ 179
           ++    + + +N+ +A++         VNI  +D+A G P L LGL+W II    +SDI 
Sbjct: 232 KQNLSLYRRHENLTLAVNSAGAIGCTTVNIGPEDLAAGRPHLVLGLLWQIIRIGLLSDIN 411

Query: 180 VS 181
           ++
Sbjct: 412 LA 417
>05733
          Length = 1021

 Score = 57.0 bits (136), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 30/100 (30%), Positives = 53/100 (53%), Gaps = 3/100 (3%)
 Frame = +2

Query: 193 LLLWSQRMVEG--YQGLRCDNFTTSWRDGRLFNAIIHRHKPMLIDMNKVYRQTNLENLDQ 250
           LL W QR++    Y+G+   +FT+SWR G  F A+IH  +P LI    +     ++N   
Sbjct: 470 LLRWCQRVLNXGTYRGVHIIDFTSSWRSGLAFCALIHAFRPHLISPASLMECETVKNNQL 649

Query: 251 AFSVAERDLGVTRLLXXXXXXXXXXXXK-SIITYVSSLYD 289
           AF VA+++LG+  ++            K +++ Y+S  ++
Sbjct: 650 AFDVAQKELGIAPVMRGEDMAACAVPDKLTMVAYLSQFHE 769
>23752
          Length = 853

 Score = 52.8 bits (125), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 39/127 (30%), Positives = 65/127 (51%), Gaps = 4/127 (3%)
 Frame = -2

Query: 725 ALQTQWSWMLQLCCCIEAHLKENTAYFQFFSDVREAEEQLQKLQETLRRKY-SCDRTITV 783
           A+++ W WM Q+  C E HL+   AY +FF +V EAE  ++    TL R + S DR    
Sbjct: 366 AVRSNWQWMSQVMQCAEVHLRNAAAYHEFFHEVEEAEYWMEN---TLSRIHMSFDRNKLQ 196

Query: 784 TRLEDLLQDAQDEKEQLN---EYKGHLSGLAKRAKAIVQLKPRNPAHPVRGHVPLIAVCD 840
               D++    + KE L    +++  +  L  RAK +V +  R  A  ++   P+IA+ D
Sbjct: 195 GNRTDVVAIQDEIKEVLAGFLQWQTKIDYLFDRAKTVVPVPQRTTA--LKEERPVIALTD 22

Query: 841 YKQVEVT 847
           +   ++T
Sbjct: 21  FSNSQIT 1
>32088
          Length = 1928

 Score = 50.8 bits (120), Expect = 1e-05,   Method: Composition-based stats.
 Identities = 34/122 (27%), Positives = 60/122 (49%), Gaps = 13/122 (10%)
 Frame = +1

Query: 73   QKKTFTKWVN---------KHLIKAQRHISDLYEDLRDGHNLISLLEVLSGDSLPRE--- 120
            ++K F  W+N         KHL++      DL++ + DG  L  L+     +++      
Sbjct: 1264 EQKAFAAWINRHLKDDPDCKHLMEVNEEGDDLFKKVGDGILLCKLINHSVSNTIDERAIN 1443

Query: 121  KGRMR-FHKLQNVQIALDYLRHRQVKLVNIRNDDIADGNPKLTLGLIWTIILHFQISDIQ 179
            K  +  +H+ +N+ +A++         VNI  +D+A G P L LGL+W II    +SDI 
Sbjct: 1444 KSNLNVYHRHENLTLAVNSAGSIGCTTVNIGPEDLAAGRPHLVLGLLWQIIRIGLLSDIN 1623

Query: 180  VS 181
            ++
Sbjct: 1624 LA 1629
>09100
          Length = 930

 Score = 43.9 bits (102), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 30/110 (27%), Positives = 50/110 (45%), Gaps = 8/110 (7%)
 Frame = +1

Query: 73  QKKTFTKWVNKHLIK--AQRHISDLYEDLRDGHNLISLLEVLSGDSLPREKG------RM 124
           Q   +  W+N  L K      I DL  D+RDG     ++ ++S   +P  +        M
Sbjct: 463 QLSAYMAWINSQLKKKPGAHLIEDLRHDMRDGVVFADVIHIVSKQQIPGIQNVPTTLDEM 642

Query: 125 RFHKLQNVQIALDYLRHRQVKLVNIRNDDIADGNPKLTLGLIWTIILHFQ 174
           R    QNV   L ++   ++K+  I + DI +GN K  + LI  +  H++
Sbjct: 643 R----QNVDRVLHFMTQNRIKMHRISSRDIVEGNLKAVMRLILALAAHYK 780
>04951
          Length = 2852

 Score = 43.5 bits (101), Expect = 0.002,   Method: Composition-based stats.
 Identities = 34/140 (24%), Positives = 66/140 (47%), Gaps = 4/140 (2%)
 Frame = +1

Query: 128 KLQNVQIALDY---LRHRQVKLVNIRNDDIADGNPKLTLGLIWTIILHFQISDIQVSGQS 184
           K++N + A+     ++  ++KLV I   DI DGNP LTLGL+W ++  + ++ +    + 
Sbjct: 4   KIENCEYAVQLGPQMKVCKMKLVGIGGKDIHDGNPVLTLGLVWQLMRAYTLAILSKLTED 183

Query: 185 EDMTAKEKLLLWSQRMVEGYQGLRCDNFTTS-WRDGRLFNAIIHRHKPMLIDMNKVYRQT 243
           +      +++ W    V+  +  R  +F  S   DG +   +I   KP +++   +    
Sbjct: 184 KKPIQDSEIVDWVNSKVKKDE--RIGSFQDSKLNDGVIVAKVIESIKPGIVNWENI--NP 351

Query: 244 NLENLDQAFSVAERDLGVTR 263
           N    D   + A   +G+ R
Sbjct: 352 NASEPDDRLANARYAIGLAR 411
>18202
          Length = 424

 Score = 43.1 bits (100), Expect = 0.003,   Method: Composition-based stats.
 Identities = 32/127 (25%), Positives = 64/127 (50%), Gaps = 3/127 (2%)
 Frame = -1

Query: 75  KTFTKWVNKHLIKAQRHISDLYEDLRDGHNLISLLEVLSGDS--LPREKGRMRFHKLQNV 132
           + +  W N  L +    + ++   +++G  L  L++VL+ ++  L + +   +  +   +
Sbjct: 385 QVYLSWANSVLCEVNSSVENV-SSIQEGRVLCELIDVLAPEAGLLDKVQASGKSGQRAFI 209

Query: 133 QIALDYLRHRQVKLVNIRNDDIADGNPKLTLGLIWTIILHFQISDI-QVSGQSEDMTAKE 191
             ALD++++  +K+V     DI DG+ K  L ++W +IL++ I  I   S Q      K+
Sbjct: 208 YAALDHMKNHGIKIV-FSTQDIMDGDIKSLLDVMWLLILNYGIHFIGNNSFQRSVGAGKK 32

Query: 192 KLLLWSQ 198
            LL W Q
Sbjct: 31  NLLDWCQ 11
>32371
          Length = 625

 Score = 26.9 bits (58), Expect(2) = 0.63,   Method: Compositional matrix adjust.
 Identities = 13/35 (37%), Positives = 22/35 (62%)
 Frame = -2

Query: 231 PMLIDMNKVYRQTNLENLDQAFSVAERDLGVTRLL 265
           P LID + + ++  L N + AF+VAE++L +   L
Sbjct: 549 PDLIDYDSLSKENVLYNNNLAFTVAEQELDIPAFL 445

 Score = 26.6 bits (57), Expect(2) = 0.63,   Method: Composition-based stats.
 Identities = 10/20 (50%), Positives = 13/20 (65%)
 Frame = -1

Query: 211 NFTTSWRDGRLFNAIIHRHK 230
           +   SWR+G  F AIIHR +
Sbjct: 610 DLLVSWRNGLAFCAIIHRFR 551
>08049
          Length = 1096

 Score = 33.9 bits (76), Expect = 1.4,   Method: Composition-based stats.
 Identities = 13/30 (43%), Positives = 17/30 (56%)
 Frame = -2

Query: 721 SFQAALQTQWSWMLQLCCCIEAHLKENTAY 750
           S+Q+    QWS +   CCCI AH  + T Y
Sbjct: 633 SWQSTFMMQWSQLRNDCCCIHAHR*DETHY 544
>02896
          Length = 2076

 Score = 31.6 bits (70), Expect = 7.2,   Method: Compositional matrix adjust.
 Identities = 13/33 (39%), Positives = 24/33 (72%)
 Frame = +1

Query: 1141 AQAVPATLQELEATKASLKKLRAQAEAQQPVFN 1173
            A+ V  T ++++ T+ +L +LRA+ EA+ PV+N
Sbjct: 1327 AKKVNTTKEDIDTTRHTLDRLRAEREAEGPVYN 1425
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|213688406|ref|NP_062656.3| dynein light chain
LC8-type 1 [Mus musculus]
         (89 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

01814                                                                 176   2e-45
23693                                                                 176   2e-45
01266                                                                 175   3e-45
07799                                                                  64   2e-11
00691                                                                  60   3e-10
31148                                                                  52   6e-08
12798                                                                  46   3e-06
01422                                                                  28   0.78 
00539                                                                  26   3.9  
10347                                                                  25   6.0  
>01814
          Length = 605

 Score =  176 bits (446), Expect = 2e-45,   Method: Compositional matrix adjust.
 Identities = 80/89 (89%), Positives = 88/89 (98%)
 Frame = +3

Query: 1   MCDRKAVIKNADMSEEMQQDSVECATQALEKYNIEKDIAAHIKKEFDKKYNPTWHCIVGR 60
           M +RKAVIKNADM+E+MQQD+V+CATQALEKYNIEKDIAA++KKEFDKKYNPTWHCIVGR
Sbjct: 96  MSERKAVIKNADMAEDMQQDAVDCATQALEKYNIEKDIAAYVKKEFDKKYNPTWHCIVGR 275

Query: 61  NFGSYVTHETKHFIYFYLGQVAILLFKSG 89
           NFGSYVTHETKHFIYFYLGQVA+LLFKSG
Sbjct: 276 NFGSYVTHETKHFIYFYLGQVAMLLFKSG 362
>23693
          Length = 1305

 Score =  176 bits (446), Expect = 2e-45,   Method: Compositional matrix adjust.
 Identities = 82/89 (92%), Positives = 87/89 (97%)
 Frame = -3

Query: 1    MCDRKAVIKNADMSEEMQQDSVECATQALEKYNIEKDIAAHIKKEFDKKYNPTWHCIVGR 60
            M +RKAVIKNADM+E+MQQD+V+CATQALEKYNIEKDIAA IKKEFDKKYNPTWHCIVGR
Sbjct: 1099 MSERKAVIKNADMAEDMQQDAVDCATQALEKYNIEKDIAAFIKKEFDKKYNPTWHCIVGR 920

Query: 61   NFGSYVTHETKHFIYFYLGQVAILLFKSG 89
            NFGSYVTHETKHFIYFYLGQVAILLFKSG
Sbjct: 919  NFGSYVTHETKHFIYFYLGQVAILLFKSG 833
>01266
          Length = 1690

 Score =  175 bits (444), Expect = 3e-45,   Method: Compositional matrix adjust.
 Identities = 80/89 (89%), Positives = 87/89 (97%)
 Frame = -1

Query: 1    MCDRKAVIKNADMSEEMQQDSVECATQALEKYNIEKDIAAHIKKEFDKKYNPTWHCIVGR 60
            M +RKAVIKNADM+E+MQQD+V+CATQALEKYNIEKDIAA IKKEFDKKYNPTWHCIVGR
Sbjct: 1594 MSERKAVIKNADMAEDMQQDAVDCATQALEKYNIEKDIAAFIKKEFDKKYNPTWHCIVGR 1415

Query: 61   NFGSYVTHETKHFIYFYLGQVAILLFKSG 89
            NFGSYVTHETKHF+YFYLGQVA+LLFKSG
Sbjct: 1414 NFGSYVTHETKHFVYFYLGQVAVLLFKSG 1328
>07799
          Length = 1797

 Score = 63.9 bits (154), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 31/83 (37%), Positives = 54/83 (65%), Gaps = 2/83 (2%)
 Frame = +1

Query: 7   VIKNADMSEEMQQDSVECATQALEKYNIEKDIAAH-IKKEFDKKYNPTWHCIVGRNFGSY 65
           +I+++DM++EM+ +++E    A EK+    + AA  IK   DKK+  +WH +VG  +G  
Sbjct: 802 LIRHSDMNDEMKTEAMELCVTACEKFASNNENAAKMIKDTMDKKFGASWHAVVGEGYGFE 981

Query: 66  VTHETKHFIY-FYLGQVAILLFK 87
           +THE K+ +Y F+ G +AI ++K
Sbjct: 982 ITHEVKNLLYMFFGGNMAICVWK 1050
>00691
          Length = 933

 Score = 59.7 bits (143), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 27/29 (93%), Positives = 29/29 (100%)
 Frame = +3

Query: 61  NFGSYVTHETKHFIYFYLGQVAILLFKSG 89
           +FGSYVTHETKHFIYFYLGQVA+LLFKSG
Sbjct: 114 HFGSYVTHETKHFIYFYLGQVAMLLFKSG 200
>31148
          Length = 442

 Score = 52.0 bits (123), Expect = 6e-08,   Method: Compositional matrix adjust.
 Identities = 26/84 (30%), Positives = 52/84 (61%), Gaps = 2/84 (2%)
 Frame = -1

Query: 6   AVIKNADMSEEMQQDSVECATQALEKYNIEK-DIAAHIKKEFDKKYNPTWHCIVGRNFGS 64
            +I+++DM++EM+ +++E    A EK   +  + +   ++   +K+  +WH +VG  FG 
Sbjct: 334 PLIRHSDMNDEMKTEAMELCVTACEKICKQ**ECSQDDQRHNGQKFGASWHAVVGEGFGF 155

Query: 65  YVTHETKHFIY-FYLGQVAILLFK 87
            +THE K+ +Y F+ G +AI ++K
Sbjct: 154 EITHEVKNLLYMFFGGNLAICIWK 83
>12798
          Length = 358

 Score = 46.2 bits (108), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 21/58 (36%), Positives = 37/58 (63%), Gaps = 1/58 (1%)
 Frame = +3

Query: 7   VIKNADMSEEMQQDSVECATQALEKYNIEKDIAAH-IKKEFDKKYNPTWHCIVGRNFG 63
           +I+++DM++EM+ +++E    A EK+    + AA  IK   DKK+  +WH +VG  +G
Sbjct: 168 LIRHSDMNDEMKTEAMELCVTACEKFASNNENAAKMIKDTMDKKFGASWHAVVGEGYG 341
>01422
          Length = 1823

 Score = 28.5 bits (62), Expect = 0.78,   Method: Composition-based stats.
 Identities = 12/17 (70%), Positives = 14/17 (82%)
 Frame = -3

Query: 72   HFIYFYLGQVAILLFKS 88
            +FIY YLGQVA+ L KS
Sbjct: 1434 NFIYIYLGQVAVKLLKS 1384
>00539
          Length = 1372

 Score = 26.2 bits (56), Expect = 3.9,   Method: Composition-based stats.
 Identities = 11/17 (64%), Positives = 13/17 (76%)
 Frame = +1

Query: 72  HFIYFYLGQVAILLFKS 88
           +FIY  LGQVA+ L KS
Sbjct: 457 NFIYIXLGQVAVKLLKS 507
>10347
          Length = 1123

 Score = 25.4 bits (54), Expect = 6.0,   Method: Composition-based stats.
 Identities = 13/38 (34%), Positives = 17/38 (44%), Gaps = 5/38 (13%)
 Frame = +3

Query: 54  WHCIVGRNFGSYVTHETKHFIYFY-----LGQVAILLF 86
           W C+ G  F  +V H     +Y Y     LG V  LL+
Sbjct: 282 WGCLFGLGFCLFVPHGIFFILYLYSNRINLGHVDCLLY 395
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|27370466|ref|NP_766540.1| gephyrin [Mus musculus]
         (769 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

13920                                                                 180   2e-45
08849                                                                  55   1e-07
05569                                                                  52   7e-07
>13920
          Length = 446

 Score =  180 bits (456), Expect = 2e-45,   Method: Compositional matrix adjust.
 Identities = 87/144 (60%), Positives = 109/144 (75%)
 Frame = -3

Query: 494 GHDIKRGECVLAKGTHMGPSEIGLLATVGVTEVEVNKFPVVAVMSTGNELLNPEDDLLPG 553
           G DI  G+ VL +G  +GP+E+GLLATVGVT V   + PVVAVMSTGNEL+ P + L  G
Sbjct: 435 GRDIAAGQQVLCRGQRLGPAELGLLATVGVTSVPCYRVPVVAVMSTGNELVEPSEPLTAG 256

Query: 554 KIRDSNRSTLLATIQEHGYPTINLGIVGDNPDDLLNALNEGISRADVIITSGGVSMGEKD 613
           KIRDSNR+TLLA ++E G   +++GI  D+PD LL  +   + +AD+I+TSGGVSMG+KD
Sbjct: 255 KIRDSNRTTLLAQLREMGVKPLDMGIAPDSPDALLKMMRGAMEKADIIVTSGGVSMGDKD 76

Query: 614 YLKQVLDIDLHAQIHFGRVFMKPG 637
           YLKQVL+ DL A IHF RVFMKPG
Sbjct: 75  YLKQVLETDLKATIHFARVFMKPG 4
>08849
          Length = 422

 Score = 54.7 bits (130), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 26/53 (49%), Positives = 37/53 (69%)
 Frame = -2

Query: 717 EPLPWAQSTGNQMSSRLMSMRSANGLLMLPPKTEQYVELHKGEVVDVMVIGRL 769
           E +  A STGNQ+SSRL+S+R AN LL LPP+++    + +G +VD +VI  L
Sbjct: 412 EDVGRAVSTGNQISSRLLSLRQANVLLRLPPRSQDLTHVQEGAIVDAIVISSL 254
>05569
          Length = 1143

 Score = 52.4 bits (124), Expect = 7e-07,   Method: Compositional matrix adjust.
 Identities = 26/53 (49%), Positives = 36/53 (67%)
 Frame = +2

Query: 717 EPLPWAQSTGNQMSSRLMSMRSANGLLMLPPKTEQYVELHKGEVVDVMVIGRL 769
           E +  A STGNQ+SSRL+S+R AN LL LPP+++    + +G  VD +VI  L
Sbjct: 11  EDVGRAVSTGNQISSRLLSLRQANVLLRLPPRSQDLTHVZEGAXVDAIVISSL 169
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|29789195|ref|NP_081729.1| basic transcription factor
3-like 4 [Mus musculus]
         (158 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

05631                                                                 177   2e-45
08594                                                                  56   6e-09
>05631
          Length = 1440

 Score =  177 bits (449), Expect = 2e-45,   Method: Compositional matrix adjust.
 Identities = 95/157 (60%), Positives = 105/157 (66%), Gaps = 3/157 (1%)
 Frame = -2

Query: 1   MNQEKLAKLQA---QVRIGGKGTARRKKKVVHRTATADDXXXXXXXXXXAVNNIAGIEEV 57
           MN EKL +LQA   QVRIGGKG+ARRKKKV+HRTAT DD          +VN I GIEEV
Sbjct: 818 MNPEKLKQLQAKADQVRIGGKGSARRKKKVIHRTATTDDKKLQSSLKKLSVNTIPGIEEV 639

Query: 58  NMIKDDGTVIHFNNPKVQASLSANTFAITGHAEAKPITEMLPGILSQLGADSLTSLRKLA 117
           NMIK+DG VIHFNNPKVQASL+ANTFA+TGHAE K I EMLPGIL+QLG +SL+SLRKLA
Sbjct: 638 NMIKEDGQVIHFNNPKVQASLAANTFAVTGHAEIKQIAEMLPGILNQLGTESLSSLRKLA 459

Query: 118 EQFPRQVLDSKAPKXXXXXXXXXXXXXXXXNFDEASK 154
                   D                     NFDEASK
Sbjct: 458 STVANAAGDVAKQNAADEDDDDDDVPELVGNFDEASK 348
>08594
          Length = 360

 Score = 55.8 bits (133), Expect = 6e-09,   Method: Compositional matrix adjust.
 Identities = 28/39 (71%), Positives = 33/39 (84%), Gaps = 3/39 (7%)
 Frame = -1

Query: 1   MNQEKLAKLQA---QVRIGGKGTARRKKKVVHRTATADD 36
           + +EKL +LQA   QVRIGGKG+ARRKKKV+HRTAT DD
Sbjct: 153 IEEEKLKQLQAKADQVRIGGKGSARRKKKVIHRTATTDD 37
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|84875524|ref|NP_001034181.1| target of myb1-like 2
isoform b [Mus musculus]
         (487 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

30964                                                                 176   2e-45
30899                                                                  68   1e-11
14965                                                                  41   0.001
>30964
          Length = 894

 Score =  176 bits (446), Expect(2) = 2e-45,   Method: Compositional matrix adjust.
 Identities = 82/130 (63%), Positives = 100/130 (76%), Gaps = 2/130 (1%)
 Frame = -1

Query: 43  TEEGPKDAIRALKKRLSGN--RNYREVMLALTVLETCVKNCGHRFHLLVANRDFIDSVLV 100
           T+EGPKDA RA KKRLS N  +N+  +M  LT LETCVKNCG RFH+ VA +DF+   LV
Sbjct: 864 TDEGPKDASRAFKKRLSQNVGKNFTAIMYTLTCLETCVKNCGRRFHVCVATKDFLQE-LV 688

Query: 101 KIISPKNNPPTIVQDKVLALIQAWADAFRSSPDLTGVVHIYEELKRRGIEFPMADLDALS 160
           K+I PK++PP  VQ+KVL +IQ WADAFR +P+L  V  IY+ELK +GIEFPM DLD ++
Sbjct: 687 KVIGPKHDPPQAVQEKVLQMIQTWADAFRGAPELKEVEKIYQELKSKGIEFPMTDLDNMA 508

Query: 161 PIHTPQRSVP 170
           PIHTP RSVP
Sbjct: 507 PIHTPARSVP 478

 Score = 25.0 bits (53), Expect(2) = 2e-45,   Method: Compositional matrix adjust.
 Identities = 9/15 (60%), Positives = 12/15 (80%)
 Frame = -2

Query: 34  MEICDIINETEEGPK 48
           ME+CD+INE  + PK
Sbjct: 890 MEVCDMINEQTKDPK 846

 Score =  120 bits (300), Expect = 2e-27,   Method: Compositional matrix adjust.
 Identities = 57/100 (57%), Positives = 71/100 (71%)
 Frame = -3

Query: 213 PITANSEQIARLRSELDIVRGNTKVMSEMLTEMVPGXXXXXXXXXXXXXNRTCRAMQHRI 272
           P T N++Q ++L  EL++V GN +VM EMLTEM P              +RTCR MQ R+
Sbjct: 358 PTTLNTDQRSKLSRELEVVSGNVRVMGEMLTEMSPSSPDASDMELLQELHRTCRQMQQRV 179

Query: 273 VELISRVSNEEVTEELLHVNDDLNNVFLRYERFERYRSGR 312
           ++L+  V+NEEVT ELL VNDDLNNVFLRYERFERYRSG+
Sbjct: 178 MQLLGEVANEEVTGELLRVNDDLNNVFLRYERFERYRSGQ 59
>30899
          Length = 698

 Score = 67.8 bits (164), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 35/92 (38%), Positives = 53/92 (57%)
 Frame = -3

Query: 3   FLLGNPFSTPVGQCLEKATDGSLQSEDWTLNMEICDIINETEEGPKDAIRALKKRLSGNR 62
           F   +PF   V    EKAT     SEDW L ++IC+ +   + G +D ++++ KRL+   
Sbjct: 684 FAATSPFDVDV----EKATHEMSTSEDWGLILDICEKVGRQQNGARDCLKSIVKRLNHKV 517

Query: 63  NYREVMLALTVLETCVKNCGHRFHLLVANRDF 94
            +   M ALT+L+ CV NCG +FHL + +RD 
Sbjct: 516 PF-VAMQALTLLDACVNNCGRQFHLEICSRDL 424
>14965
          Length = 949

 Score = 40.8 bits (94), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 36/123 (29%), Positives = 52/123 (42%), Gaps = 1/123 (0%)
 Frame = +2

Query: 366 ESVSGTLSSLQQCKPQDGFDMFA-QTRGNSLAEQRKTVTYEDPQAVGGLASALDNRKQNS 424
           + ++G LS     KPQ   D+   Q +     E  + +   DP A             NS
Sbjct: 92  DQLTGALSQTAASKPQSDNDILNLQDKDTDYDEMEQWLATHDPNAAA-----------NS 238

Query: 425 EMKGDDLEEGVTSEEFDKFLEERAKAAETVPDLXXXXXXXXXXXXXXXXRKKPERSDDAL 484
             +    +EG+TS EFD+FL ERA AAE +P +                R + ++S   L
Sbjct: 239 GAR----QEGLTSSEFDRFLLERAAAAENMPTIPAQTGPQSARNTRQMKRDEEDKS---L 397

Query: 485 FAL 487
           FAL
Sbjct: 398 FAL 406
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|9789991|ref|NP_062631.1| hydroxysteroid (17-beta)
dehydrogenase 12 protein [Mus musculus]
         (312 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

18041                                                                 178   2e-45
03060                                                                  77   1e-14
05690                                                                  67   7e-12
03983                                                                  67   1e-11
07400                                                                  52   4e-07
05194                                                                  51   6e-07
36378                                                                  50   1e-06
18534                                                                  49   2e-06
23588                                                                  48   4e-06
36857                                                                  46   2e-05
30783                                                                  44   6e-05
35967                                                                  42   3e-04
05235                                                                  37   0.008
11922                                                                  37   0.009
27168                                                                  31   0.51 
02298                                                                  31   0.65 
37635                                                                  28   5.2  
>18041
          Length = 547

 Score =  178 bits (451), Expect = 2e-45,   Method: Compositional matrix adjust.
 Identities = 85/182 (46%), Positives = 128/182 (70%), Gaps = 1/182 (0%)
 Frame = -2

Query: 57  GGTDGIGKAYAEELAKRGMKIVLISRSQDKLNQVSNNIKEKFNVETRTIAVDFSLDDIYD 116
           G TDGIGK +A +LA++G+ IVLISR+ +KL+ V+  I ++  V  + I  DF   DIYD
Sbjct: 546 GSTDGIGKCFALQLAEKGLDIVLISRNPEKLSAVAKEIVDQHKVSVKVITADFKNADIYD 367

Query: 117 KIKTGLSGLEIGVLVNNVGM-SYEYPEYFLEIPDLDNTIKKLININVLSVCKVTRLVLPG 175
            IK  L+GL+IG+LVNNVGM +   P YF E  D +   + +IN+N+L+  ++T +VLP 
Sbjct: 366 NIKRQLTGLDIGILVNNVGMLNRRNPGYFCEADDFEQFHQDIINVNILACVQMTGIVLPE 187

Query: 176 MVERSKGVILNISSASGMLPVPLLTIYSATKAFVDFFSQCLHEEYKSKGIFVQSVMPYLV 235
           M+ER +G+I+NI+S + + P+P  ++YS TKAF+  F+Q L+ EY S+G+ +Q ++P LV
Sbjct: 186 MLERKRGLIINIASGAAIRPLPFFSVYSGTKAFISHFTQALNMEYSSQGVTIQLLIPNLV 7

Query: 236 AT 237
           AT
Sbjct: 6   AT 1
>03060
          Length = 1893

 Score = 76.6 bits (187), Expect = 1e-14,   Method: Compositional matrix adjust.
 Identities = 58/200 (29%), Positives = 98/200 (49%), Gaps = 9/200 (4%)
 Frame = -1

Query: 50   GEWAVVTGGTDGIGKAYAEELAKRGMKIVLISRSQDKLNQVSNNIK----EKFNVETRTI 105
            G+  +VTG + G+GKA A+   + G +++L  RS ++LN V + +     E    E   +
Sbjct: 1689 GKVVLVTGASSGLGKACAKVFHQHGCQVILAGRSVERLNAVKDYLTKSEGEVKACEPSVL 1510

Query: 106  AVDFSLDDIYDKIKTGLSGLE----IGVLVNNVGMSYEYPEYFLEIPDLDNTI-KKLINI 160
            A+D  L+D+    +     +E    + V++NN G+SY        I D    + +KL+ +
Sbjct: 1509 AMD--LEDLNSLQQLAERAVELFGKVDVVINNAGISYRGC-----IEDTSIQVDQKLMAV 1351

Query: 161  NVLSVCKVTRLVLPGMVERSKGVILNISSASGMLPVPLLTIYSATKAFVDFFSQCLHEEY 220
            N      + + +LP M  R+ G I+ ISS  G + +P  + YSA+K  +  F  CL  E 
Sbjct: 1350 NYFGHVALIKGLLPHMQARNSGHIVGISSVQGKISIPYRSAYSASKHALQAFFDCLRAEL 1171

Query: 221  KSKGIFVQSVMPYLVATKLA 240
                I V  + P  + T L+
Sbjct: 1170 SCTKIKVSLLSPGYIKTNLS 1111
>05690
          Length = 1192

 Score = 67.4 bits (163), Expect = 7e-12,   Method: Compositional matrix adjust.
 Identities = 66/265 (24%), Positives = 120/265 (45%), Gaps = 19/265 (7%)
 Frame = +2

Query: 47  PRLGEWAVVTGGTDGIGKAYAEELAKRGMKIVLISRSQDKLNQVSNNIKEKFNVETRTIA 106
           P  G+   +TG   G+G   A  L K G+K+   +       +    +K K +    T+ 
Sbjct: 164 PAEGKAVFITGCDAGLGHLLAIHLDKLGVKV--FAGCLFPGGEGEQTLKAKCSQRLCTVP 337

Query: 107 VDFSLDDIY----DKIKTGLSGLEIGVLVNNVGMSYEYPEYFLEIPDLDNTIKKLININV 162
           +D    +I     D +K  L G E+  +VNN G+ +      +   D+D    K++++N 
Sbjct: 338 LDVCSLEIVTTAADTVKRELDGQELWGVVNNAGIMHIGCLEVMGQADVD----KILDVNY 505

Query: 163 LSVCKVTRLVLPGMVERSKGVILNISSASGMLPVPLLTIYSATKAFVDFFSQCLHEEYKS 222
                V R  LP  + RS+G ++N++S +G+ PVP   +Y A+KA V   ++ L  E + 
Sbjct: 506 RGQVNVIRAFLP-FLRRSRGRLVNVASNTGIAPVPYHAVYCASKAAVAALTESLRLELQP 682

Query: 223 KGIFVQSVMPYLVATKLAKIQKPTL-DK--PSAETFVKSAI--KTVGLQTRTTGY----- 272
            G+ V +++P    T + +    T  DK    A+  V+ +    +   Q +T  Y     
Sbjct: 683 FGVRVSTIIPSGYRTGIQQHNTQTTGDKWWAQAKQEVRDSYGHDSFTPQNKTKDYKSYLN 862

Query: 273 -----VIHSLMGSINSIMPRWMYFK 292
                +IH +  ++  + P+  Y+K
Sbjct: 863 ADFSGIIHKMSDALLEMCPQDYYYK 937
>03983
          Length = 1099

 Score = 66.6 bits (161), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 59/226 (26%), Positives = 108/226 (47%), Gaps = 16/226 (7%)
 Frame = +2

Query: 30  LFRAFQVWCVGNEALVGPRL----------GEWAVVTGGTDGIGKAYAEELAKRGMKIVL 79
           L +    WC   EA+V   L          G+  ++TG   G+GK  A      G  +VL
Sbjct: 95  LLKVMYYWC---EAIVKCILPSKFFRKSVEGQRVLITGAGSGLGKLMAYRFMGLGCDLVL 265

Query: 80  ISRSQDKLNQVSNNIKEKFNVETRTIAVDFSLDDIY---DKIKTGLSGLEIGVLVNNVGM 136
              + + +  +  ++ ++ + +  T+ +  S + IY   D++K  + G++I  LVNN G+
Sbjct: 266 WDINTEAIEAMERDMGQQVSCKAYTVDLS-SREQIYKAADQVKREVGGVDI--LVNNAGI 436

Query: 137 SYEYPEYFLEIPDLDNTIKKLININVLSVCKVTRLVLPGMVERSKGVILNISSASGMLPV 196
                  FL+ P  D+ I+K + +N  +     +  LP M+ ++KG I++I+S++G+  V
Sbjct: 437 V--TGRKFLDCP--DSLIEKTMEVNSNAHFWTVKAFLPNMLAQNKGHIISIASSAGLFGV 604

Query: 197 PLLTIYSATKAFVDFFSQCLHEEYKS---KGIFVQSVMPYLVATKL 239
             L  Y A+K     F + L  E ++    G+    V PY + T +
Sbjct: 605 TGLADYCASKFAAVGFDESLRFELEAMGKTGVHTTVVCPYFINTGM 742
>07400
          Length = 1577

 Score = 51.6 bits (122), Expect = 4e-07,   Method: Compositional matrix adjust.
 Identities = 50/190 (26%), Positives = 84/190 (44%), Gaps = 4/190 (2%)
 Frame = -3

Query: 47   PRLGEWAVVTGGTDGIGKAYAEELAKRGMKIVLISRSQDKLNQVSNNIKEKFNVETRTIA 106
            P   +  ++TG   GIG   A E  KRG+ +V  +   D  +  +  + EK  V    I 
Sbjct: 1449 PAKDKVVLITGCDTGIGHEAALEANKRGLTVV--AGCLDVTSSGAQRLAEKKGVH--VIR 1282

Query: 107  VDFSLDDIYDKIKTGLSGL----EIGVLVNNVGMSYEYPEYFLEIPDLDNTIKKLININV 162
            +D S D+        +S L     +  ++NN G +   P   +E+  +  T   + ++ +
Sbjct: 1281 LDVSSDESVANAMKSVSKLCEAKGLWAVINNAGFNRMSP---VELTSM-TTFHHVADVML 1114

Query: 163  LSVCKVTRLVLPGMVERSKGVILNISSASGMLPVPLLTIYSATKAFVDFFSQCLHEEYKS 222
                +VT+ VLP +V R+KG ++ +SS  GM      + Y   K  V+ FS     E K 
Sbjct: 1113 FGTVRVTKAVLP-LVRRAKGRVVTVSSDRGMTTPAYSSAYCIAKFGVEAFSDVXRMEMKK 937

Query: 223  KGIFVQSVMP 232
              + V  + P
Sbjct: 936  YDVSVSIIQP 907
>05194
          Length = 1075

 Score = 51.2 bits (121), Expect = 6e-07,   Method: Compositional matrix adjust.
 Identities = 27/68 (39%), Positives = 37/68 (54%)
 Frame = +1

Query: 172 VLPGMVERSKGVILNISSASGMLPVPLLTIYSATKAFVDFFSQCLHEEYKSKGIFVQSVM 231
           +  GMV+R  G I+NISS +G    P L +YS +K FV+  SQ +  E    G+ V  + 
Sbjct: 10  ITAGMVKRESGHIINISSDAGRKGFPGLAVYSGSKFFVEGLSQAMRSEVADSGVKVTCIQ 189

Query: 232 PYLVATKL 239
           P  V T L
Sbjct: 190 PGDVKTPL 213
>36378
          Length = 552

 Score = 50.1 bits (118), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 29/94 (30%), Positives = 54/94 (57%)
 Frame = -3

Query: 126 EIGVLVNNVGMSYEYPEYFLEIPDLDNTIKKLININVLSVCKVTRLVLPGMVERSKGVIL 185
           +I +LVNN G S +  E+     D+D   ++++ +NVL V  +T+ VLP M++R +G ++
Sbjct: 367 QIDILVNNAGRS-QRAEWVKTSLDVD---RQMLELNVLGVLSLTKAVLPHMMQRGRGHMV 200

Query: 186 NISSASGMLPVPLLTIYSATKAFVDFFSQCLHEE 219
            +SS +G    P+   Y+ +K  +  + + L  E
Sbjct: 199 VMSSIAGKCGAPMSGSYTGSKHALHGWFESLRVE 98
>18534
          Length = 406

 Score = 48.9 bits (115), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 34/111 (30%), Positives = 55/111 (49%), Gaps = 3/111 (2%)
 Frame = -2

Query: 126 EIGVLVNNVGMSYEYPEYFLEIPDLDNTIKKLININVLSVCKVTRLVLPGMVERSKGVIL 185
            + VL+NN G+    P  F E+ D    I+   NIN++S     +  LP M+  ++G I+
Sbjct: 324 HVDVLINNAGIVCCKP--FWELHD--RVIQNTYNINIISHYWTVKAFLPHMMRHNRGHIV 157

Query: 186 NISSASGMLPVPLLTIYSATKAFVDFFSQCLHEEYKSKG---IFVQSVMPY 233
            + S +GML     + Y+ATK     F + L  + K+ G   I +  + PY
Sbjct: 156 TVGSVTGMLGTYGCSDYAATKYACIGFHESLLTDLKAHGYDQIHMSLICPY 4
>23588
          Length = 611

 Score = 48.1 bits (113), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 47/166 (28%), Positives = 75/166 (45%), Gaps = 4/166 (2%)
 Frame = +3

Query: 62  IGKAYAEELAKRGMKIVLISRSQDKLNQVSNNIKEKFNVETRTIAVDFSLDDIYDKIKTG 121
           IG   A  L +RG ++ L  R   KL  V           T  + V   L D   + +  
Sbjct: 3   IGAGIAVCLGERGARLSLTGRDATKLENVVQKCVAAGVKPTDVVTVAGDLTDETFRQQLV 182

Query: 122 LSGL----EIGVLVNNVGMSYEYPEYFLEIPDLDNTIKKLININVLSVCKVTRLVLPGMV 177
            S +    +I VLVNN G +       L  P ++N +  + ++N+ +   +++L +P ++
Sbjct: 183 ASTVDKFGQIDVLVNNAGFANPG---LLSBPGMENLLN-VFSLNLNAHVAMSKLCVPHLL 350

Query: 178 ERSKGVILNISSASGMLPVPLLTIYSATKAFVDFFSQCLHEEYKSK 223
           + SKG I+NISS   M P P L  Y  +K     F++ L  E   K
Sbjct: 351 Q-SKGNIVNISSNLSMRPSPALGAYCMSKRHWTCFTRVLAYELAPK 485
>36857
          Length = 697

 Score = 46.2 bits (108), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 25/58 (43%), Positives = 35/58 (60%), Gaps = 2/58 (3%)
 Frame = +3

Query: 184 ILNISSASGMLPVPLLTIYSATKAFVDFFSQCL--HEEYKSKGIFVQSVMPYLVATKL 239
           I+NISSA G+ P P+  +Y  TKA V  FS+ +  H++Y   GI V ++ P  V T L
Sbjct: 267 IINISSAGGLRPQPVGPVYCGTKAGVMMFSRSVAAHKDYIDNGIRVNTLCPAFVDTPL 440
>30783
          Length = 765

 Score = 44.3 bits (103), Expect = 6e-05,   Method: Compositional matrix adjust.
 Identities = 21/53 (39%), Positives = 31/53 (58%)
 Frame = +1

Query: 180 SKGVILNISSASGMLPVPLLTIYSATKAFVDFFSQCLHEEYKSKGIFVQSVMP 232
           +KG I+N+SS     P+  + +Y  +KA +D F+QCL  E    G+ V SV P
Sbjct: 175 TKGCIVNVSSICASRPMAEVGVYCMSKAAMDMFTQCLALELAPHGVRVNSVNP 333
>35967
          Length = 169

 Score = 42.0 bits (97), Expect = 3e-04,   Method: Composition-based stats.
 Identities = 19/47 (40%), Positives = 31/47 (65%)
 Frame = +2

Query: 181 KGVILNISSASGMLPVPLLTIYSATKAFVDFFSQCLHEEYKSKGIFV 227
           K  I+N SS+S +   P ++IY+ATKA+   FS+C+ +EY+ +   V
Sbjct: 29  KSAIINFSSSSVVDQDPRISIYAATKAYNHVFSECMRKEYEEESHLV 169
>05235
          Length = 944

 Score = 37.4 bits (85), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 54/221 (24%), Positives = 93/221 (42%), Gaps = 8/221 (3%)
 Frame = -2

Query: 50  GEWAVVTGGTDGIGKAYAEELAKRGMK-IVLISRSQDKLNQVS-NNIKEKFNVETRTIAV 107
           G+  +   G  GIG     E+ K G K +V++ R ++         I  K  +      V
Sbjct: 871 GKNIIFVAGLGGIGLDTNHEIVKSGPKNLVILDRIENPAAIAELKAINPKVTISYYPYDV 692

Query: 108 DFSLDDIYDKIKTGLSGLE-IGVLVNNVGMSYEYPEYFLEIPDLDNTIKKLININVLSVC 166
             S+ +    +KT  + L+ + +L+N  G+        L+    D+ I++ I +N     
Sbjct: 691 TVSVAESVKLLKTVFAQLKKVDLLINGAGI--------LD----DHQIERTIAVNFTGTV 548

Query: 167 KVTRLVLPGMVERSKG---VILNISSASGMLPVPLLTIYSATKAFVDFFSQCLHEEYKSK 223
             T  ++    +R  G   VI NI S +G   +  + +YSA+KA    F+  L +     
Sbjct: 547 NTTTAIMEFWDKRKGGPGGVIANICSVTGFNSIYQVPVYSASKAXALSFTNSLAKLAHIT 368

Query: 224 GIFVQSVMPYLVATKLAKIQKPTLDKPS--AETFVKSAIKT 262
           G+ V S+ P +  T L       LD  S  AE  + +  +T
Sbjct: 367 GVTVYSINPGITHTPLVNKFNSWLDVESHVAEKLLANPTQT 245
>11922
          Length = 2153

 Score = 37.4 bits (85), Expect = 0.009,   Method: Compositional matrix adjust.
 Identities = 49/201 (24%), Positives = 86/201 (42%), Gaps = 11/201 (5%)
 Frame = +1

Query: 43  ALVGPRLGEWAVVTGGTDGIGKAYAEELAKRGMKIVLISRSQDKLNQVSNNI----KEKF 98
           A  G  +G+   +TG + GIGKA A +LAK G  IV+ +++ +   ++   I    KE  
Sbjct: 79  ANTGKLVGKTVFITGASRGIGKAIAVKLAKDGANIVIAAKTAEAHPKLPGTIYTAAKEVE 258

Query: 99  NVETRTIAVDFSLDDIYDKIKTGLSGLE-----IGVLVNNVGMSYEYPEYFLEIPDLDNT 153
               + +     + +  D++K  +         I +LVNN   S       L+ P     
Sbjct: 259 EAGGKALPCIVDIRN-EDQVKVAVKAAADKFGGIDILVNNA--SAISLTGTLQTPMKRYD 429

Query: 154 IKKLININVLSVCKVTRLVLPGMVERSKGVILNISSASGMLP--VPLLTIYSATKAFVDF 211
           +   IN     +C  +++ LP ++  S   ILNIS    M          Y+  K  +  
Sbjct: 430 LMNGINARGTYLC--SQVCLPYLLRGSNPHILNISPPLNMSAKWFQGHVAYTMAKYGMSM 603

Query: 212 FSQCLHEEYKSKGIFVQSVMP 232
            +  + EE++  G+ V ++ P
Sbjct: 604 CALGMAEEFRDDGVAVNALWP 666
>27168
          Length = 665

 Score = 31.2 bits (69), Expect = 0.51,   Method: Compositional matrix adjust.
 Identities = 42/161 (26%), Positives = 76/161 (47%), Gaps = 9/161 (5%)
 Frame = +3

Query: 50  GEWAVVTGGTDGIGKAYAEELAKRGMKIVLISR----SQDKLNQVSNNIKEKFNVETRTI 105
           G  A++TG   GIG   A  LA  G +I+L  R    +Q+ +++++   +       RT 
Sbjct: 186 GRVALITGANCGIGFETARSLALHGCEIILACRNLATAQEAIDRIAVE-RPAARARCRTA 362

Query: 106 AVDF-SLDDI---YDKIKTGLSGLEIGVLVNNVGMSYEYPEYFLEIPDLDNTIKKLININ 161
           ++D  SL D+    ++I+  +    I  L+ N G+ +  P Y   +  L+ T +    ++
Sbjct: 363 SLDLGSLSDVKKFVEQIRQSVG--HIDYLILNAGV-FALP-YTKTVDGLETTFQ----VS 518

Query: 162 VLSVCKVTRLVLPGMVERSKGVILNISSAS-GMLPVPLLTI 201
            LS   +T  +      R++ V+L+  S     LPV  LT+
Sbjct: 519 HLSHFYLTLQLESLFDHRTRIVVLSSESHRFASLPVENLTV 641
>02298
          Length = 1038

 Score = 30.8 bits (68), Expect = 0.65,   Method: Compositional matrix adjust.
 Identities = 13/32 (40%), Positives = 20/32 (62%)
 Frame = +3

Query: 265 LQTRTTGYVIHSLMGSINSIMPRWMYFKIIMG 296
           L+TR TGY   +L+ S +  MPRW +F + + 
Sbjct: 924 LKTRVTGYSGSTLLMSADLSMPRWSFFTLFVS 1019
>37635
          Length = 2610

 Score = 28.1 bits (61), Expect = 5.2,   Method: Compositional matrix adjust.
 Identities = 13/35 (37%), Positives = 20/35 (57%)
 Frame = +3

Query: 11   LYWVGASTIAYLALRASYSLFRAFQVWCVGNEALV 45
            LY+  + ++ +L L  S   FR F +WC+   ALV
Sbjct: 1035 LYYTCSRSLFFLLLYFSSPHFRPFSLWCLSAGALV 1139
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|13385384|ref|NP_080170.1| proteasome 26S non-ATPase
subunit 12 [Mus musculus]
         (456 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

03414                                                                 179   3e-45
20681                                                                  30   1.5  
18065                                                                  28   7.5  
>03414
          Length = 1452

 Score =  179 bits (453), Expect = 3e-45,   Method: Compositional matrix adjust.
 Identities = 86/144 (59%), Positives = 112/144 (77%), Gaps = 1/144 (0%)
 Frame = +2

Query: 314 LMRWSTLVEDYGVELRKGSSETPATDVFSSTEE-GEKRWKDLKSRVVEHNIRIMAKYYTR 372
           L++W TL +++ +E++ GS+  P T VF+  +E G KRW DLK RVVEHNIR+MAKYYTR
Sbjct: 2   LIQWKTLCQNFEMEMKTGSATNPPTHVFNPKQENGVKRWADLKIRVVEHNIRVMAKYYTR 181

Query: 373 ITMKRMAQLLDLSVDESEAFLSNLVVNKTIFAKVDRLAGVINFQRPKDPNNLLNDWSQKL 432
           I +KRM++LLDL+  E+E FLS LVV  T+ AK+DRLAGV+ F   KDP+++LN+W+ KL
Sbjct: 182 IRIKRMSELLDLTDGETEEFLSGLVVAGTVEAKMDRLAGVVQFTPHKDPSDVLNEWAGKL 361

Query: 433 NSLMSLVNKTTHLIAKEEMIHNLQ 456
           + LMSLVNKT HLI KEEMIH L 
Sbjct: 362 SQLMSLVNKTNHLINKEEMIHVLH 433
>20681
          Length = 1217

 Score = 30.4 bits (67), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 48/178 (26%), Positives = 81/178 (45%), Gaps = 21/178 (11%)
 Frame = -3

Query: 34  LAKEGRLQEVIETLLSLEK---QTRTASDMVSTSRIL---------VAVVKMCYEAKEWD 81
           LA    L   ++ LL  E+    TRT +D+ + S +L          A +     +K  D
Sbjct: 546 LADSKNLVNKLQPLLCAERVSQMTRTYNDIDAVSNLLEEKERDLELAARIGQTLLSKNKD 367

Query: 82  L------LNENIMLLSKRRSQLKQAVAKMVQQCCTYVEEITDLPVKLRLIDTLRMVTEGK 135
           L      L E + L +    QLK  ++K VQQ   Y +++     K    D L  V  G 
Sbjct: 366 LVGRKEALEEQLSLATDTIKQLKHELSKKVQQLEVYDQDLQYQTCK----DNLASVGGGD 199

Query: 136 IYVEIERARLTKTLATIKEQNGDVK-EAASILQELQVETYGSMEKKER--VEFILEQM 190
             +++E  +L K + +++E+N  ++ E A +L + +     S E+KE+  VE  L+Q 
Sbjct: 198 ASLKVE--KLQKQVGSLEEENHSLRLETAQLLSDTE-----SHEEKEKKLVEDCLQQF 46
>18065
          Length = 868

 Score = 28.1 bits (61), Expect = 7.5,   Method: Compositional matrix adjust.
 Identities = 18/57 (31%), Positives = 26/57 (45%), Gaps = 1/57 (1%)
 Frame = -3

Query: 251 YDTPCIQAESDKWQQALKSVVLYVI-LAPFDNEQSDLVHRISSDKKLEEIPKYKDLL 306
           Y TPC     D W+Q  +SV+ YV+ ++ F     D   RI   K+      Y  L+
Sbjct: 485 YLTPCSVLIYDDWKQVNQSVIYYVLSISRFSAGSHDP*FRIPRLKRSASFKSYCSLI 315
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|19111156|ref|NP_579925.1| HELG [Mus musculus]
         (1217 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

19545                                                                 180   3e-45
09272                                                                 134   3e-31
03659                                                                 122   1e-27
12784                                                                 108   2e-23
19948                                                                 104   3e-22
20747                                                                  84   3e-16
18403                                                                  61   3e-09
17966                                                                  60   4e-09
>19545
          Length = 519

 Score =  180 bits (457), Expect = 3e-45,   Method: Composition-based stats.
 Identities = 92/168 (54%), Positives = 119/168 (70%)
 Frame = +2

Query: 503 RGARCNVIITQPRRISAVSVAQRVSHELGPSLRRNVGFQVRLESKPPARGGALLFCTVGI 562
           RGA CN+I+TQPRRISAVS+A+RV+ E    L  +VG+ VR E+  P   GA+L+CTVG 
Sbjct: 2   RGAFCNIIVTQPRRISAVSIAERVAEERSEMLGNSVGYSVRFETVMPRPYGAMLYCTVGT 181

Query: 563 LLRKLQSNPSLEGVSHVIVDEVHERDVNTDFLLILLKGLQRLNPALRLVLMSATGDNERF 622
           LLRKL+    L GVSHVIVDE+HERD+NTDFLL+LL+ + R  P LR++LMSAT D   F
Sbjct: 182 LLRKLEG--GLRGVSHVIVDEIHERDINTDFLLVLLRDMVRAYPDLRVLLMSATVDTTLF 355

Query: 623 SRYFGGCPVIKVPGFMYPVKEHYLEDILAKLGKHQYPHRHRHHESEDE 670
           + YFG C V++V G +YPV+E+YLED +  L     P+  R  +  DE
Sbjct: 356 TDYFGSCTVVEVYGRVYPVQEYYLEDCIQMLNFVPAPN-DRKRKMRDE 496
>09272
          Length = 890

 Score =  134 bits (336), Expect = 3e-31,   Method: Compositional matrix adjust.
 Identities = 90/252 (35%), Positives = 136/252 (53%), Gaps = 4/252 (1%)
 Frame = +2

Query: 723 LILPVHS-NIPMMDQKAIFQQPPLGVRKIVLATNIAETSITVNDIVHVVDSGLHKEERYD 781
           LI+P     +P   Q  IF+  P G RK+V+ATNIAETS+T+N I +VVD G  K+  Y+
Sbjct: 29  LIIPARLLRLPSEMQTRIFEPAPPGSRKVVIATNIAETSLTINGIYYVVDPGFVKQNVYN 208

Query: 782 LKTKVSCLETVWVSRANVIQRRGRAGRCQSGFAYHLFP-RSRLEKMVPFQVPEILRTPLE 840
            KT +  L    +S+A   QR GRAGR   G  Y L+  R+  ++M+P  VPEI RT L 
Sbjct: 209 SKTGMDQLIVTPISQAQAKQRAGRAGRTGPGKCYRLYTERAYRDEMLPTNVPEIQRTNLA 388

Query: 841 NLVLQAK-IHMPEKTAVEFLSKAVDSPNIKAVDEAVILLQEIGVLDQREYLTTLGQRLAH 899
           + VL  K + + +  A +F+    DSP ++ +  A+  L  +  LD    LT LG+R+A 
Sbjct: 389 STVLSLKAMGINDLLAFDFM----DSPPMQTLISAMEQLHALSALDDEGLLTRLGRRMAE 556

Query: 900 ISTDPRLAKAIVLAAIFRCLHPLLVVVSCLT-RDPFSSSLQNRAEVDKVKALLSHDSGSD 958
              +P L+K ++++    C   +L +VS L+ ++ F      +A  D+ KA   H    D
Sbjct: 557 FPLEPMLSKMLIMSVHLACSDEILTIVSMLSVQNVFYRPKDKQALADQKKAKF-HQPEGD 733

Query: 959 HLAFVRAVAGWE 970
           HL  +     W+
Sbjct: 734 HLTLLSVYNSWK 769
>03659
          Length = 1566

 Score =  122 bits (305), Expect = 1e-27,   Method: Compositional matrix adjust.
 Identities = 70/187 (37%), Positives = 110/187 (58%), Gaps = 2/187 (1%)
 Frame = -1

Query: 450 IWQEAPQLPVDPHRDTILSAIEQHPVVVISGDTGCGKTTRIPQLLLERYVTEGRGARCNV 509
           I ++   LP+   +D +L A+  + ++++ G+TG GKTT+I Q L E     G   R  +
Sbjct: 540 ILEQRQGLPIYKLKDELLKAVHDNQILIVIGETGSGKTTQITQYLAE----SGYTTRGKI 373

Query: 510 IITQPRRISAVSVAQRVSHELGPSLRRNVGFQVRLE--SKPPARGGALLFCTVGILLRKL 567
             TQPRR++A+SVA+RVS E G  L + VG+ +R E  + P  +   + + T G+LLR+ 
Sbjct: 372 GCTQPRRVAAMSVAKRVSEEFGCRLGQEVGYTIRFEDCTSPETK---IKYMTDGMLLREC 202

Query: 568 QSNPSLEGVSHVIVDEVHERDVNTDFLLILLKGLQRLNPALRLVLMSATGDNERFSRYFG 627
             +  L   S V++DE HER ++TD L  LLK   +  P L+L++ SAT D  +FS+YF 
Sbjct: 201 LIDRDLMQYSIVMLDEAHERTIHTDVLFGLLKQAVKKRPDLKLIVTSATLDAVKFSQYFF 22

Query: 628 GCPVIKV 634
             P+  +
Sbjct: 21  EAPIFTI 1
>12784
          Length = 2199

 Score =  108 bits (269), Expect = 2e-23,   Method: Compositional matrix adjust.
 Identities = 71/227 (31%), Positives = 123/227 (54%), Gaps = 3/227 (1%)
 Frame = -1

Query: 748  RKIVLATNIAETSITVNDIVHVVDSGLHKEERYDLKTKVSCLETVWVSRANVIQRRGRAG 807
            RK+V++TNIAETS+T++ +V V+D G  K++ Y+ + +V  L    +S+A+  QR GRAG
Sbjct: 2199 RKVVVSTNIAETSLTIDGVVFVIDPGFAKQKVYNPRIRVESLLVTAISKASAQQRAGRAG 2020

Query: 808  RCQSGFAYHLFP-RSRLEKMVPFQVPEILRTPLENLVLQ-AKIHMPEKTAVEFLSKAVDS 865
            R + G  + L+  ++  ++M     PEILR+ L ++VLQ  K+ + +    +F+    D 
Sbjct: 2019 RTRPGKCFRLYTEKAYTQEMQENTYPEILRSNLGSVVLQLKKLGIDDLVHFDFM----DP 1852

Query: 866  PNIKAVDEAVILLQEIGVLDQREYLTTLGQRLAHISTDPRLAKAIVLAAIFRCLHPLLVV 925
            P  + +  A+ LL  +  LD    LT LG  +A    DP+LAK ++ +    C + +L +
Sbjct: 1851 PAPETLMRALELLNYLAGLDDDGELTELGSMMAEFPLDPQLAKMVIASCDSNCSNEILSI 1672

Query: 926  VSCLTR-DPFSSSLQNRAEVDKVKALLSHDSGSDHLAFVRAVAGWEE 971
             S L+    F    + +   D+ K   +H  G DHL  +     +++
Sbjct: 1671 TSMLSVPQCFVRPTEAKKAADEAKMRFAHIDG-DHLTLLNVYHAFKQ 1534
>19948
          Length = 466

 Score =  104 bits (259), Expect = 3e-22,   Method: Compositional matrix adjust.
 Identities = 51/113 (45%), Positives = 72/113 (63%)
 Frame = +1

Query: 684 HIDARGEPGGILCFLPGWQEIKGVQQRLQEALGMHESKYLILPVHSNIPMMDQKAIFQQP 743
           +I   G PG +L FLPGW  I  +Q+ LQ +     SKY ILP+HS IP  +Q+ +F+  
Sbjct: 109 YIQGLGIPGAVLFFLPGWSLIFMIQRHLQMSPEFGSSKYCILPLHSQIPREEQRKVFEPV 288

Query: 744 PLGVRKIVLATNIAETSITVNDIVHVVDSGLHKEERYDLKTKVSCLETVWVSR 796
           P GV KI+L+TNIAETS+T+ND+V+V+DS   K + +     ++   TVW S 
Sbjct: 289 PDGVTKIILSTNIAETSVTINDVVYVIDSCKVKMKLFTSHNNMTNYATVWASN 447
>20747
          Length = 444

 Score = 84.0 bits (206), Expect = 3e-16,   Method: Compositional matrix adjust.
 Identities = 56/143 (39%), Positives = 85/143 (59%), Gaps = 7/143 (4%)
 Frame = +1

Query: 484 CGKTTRIPQLLLERYVTEGRGARCNVI-ITQPRRISAVSVAQRVSHELGPSLRRNVGFQV 542
            GKTT++PQ L E     G   +  +I +T+PRR++A+S++QRV+ E+  +  R V +Q+
Sbjct: 1   SGKTTQVPQFLYE----AGYAHKGGMIGVTEPRRVAAISMSQRVAEEMNLT-SREVSYQI 165

Query: 543 RLESKPPARGGALLFCTVGILLRKLQSNPSLEGVSHVIVDEVHERDVNTDFLLILLKGL- 601
           R E         + F T G+LLR++Q +  L   S +I+DE HER V TD L+ LL  + 
Sbjct: 166 RYEGNVTP-DTHIKFMTDGVLLREIQQDFVLSKYSVIILDEAHERSVFTDILIGLLSRIA 342

Query: 602 -----QRLNPALRLVLMSATGDN 619
                + L+P L+LV+MSAT D 
Sbjct: 343 PYRIKKNLSP-LKLVIMSATLDK 408
>18403
          Length = 434

 Score = 60.8 bits (146), Expect = 3e-09,   Method: Composition-based stats.
 Identities = 38/141 (26%), Positives = 71/141 (50%), Gaps = 2/141 (1%)
 Frame = +2

Query: 817 LFPRSRLEKMVPFQVPEILRTPLENLVLQ-AKIHMPEKTAVEFLSKAVDSPNIKAVDEAV 875
           L+  S   +   +  PEI R PL++LVLQ   + +P      F    ++ P++  ++ +V
Sbjct: 5   LYAESDYNEFEAYSTPEIQRVPLDSLVLQLISMGLPNVRKFPF----IEPPDLSTIENSV 172

Query: 876 ILLQEIGVLDQREYLTTLGQRLAHISTDPRLAKAIVLAAIFRCLHPLLVVVSCLT-RDPF 934
             L+E G L   E LT +GQ L+ +  D  + K +++ +IF  + P+L + + ++ + PF
Sbjct: 173 RFLKEQGALAGDESLTAIGQMLSMLPVDVVIGKMLIMGSIFHMVDPILSIAAAMSVQSPF 352

Query: 935 SSSLQNRAEVDKVKALLSHDS 955
           +            KA + HD+
Sbjct: 353 TG-----------KAHIDHDA 382
>17966
          Length = 424

 Score = 60.5 bits (145), Expect = 4e-09,   Method: Compositional matrix adjust.
 Identities = 45/119 (37%), Positives = 60/119 (50%)
 Frame = -1

Query: 798 NVIQRRGRAGRCQSGFAYHLFPRSRLEKMVPFQVPEILRTPLENLVLQAKIHMPEKTAVE 857
           N+ QRRGRAGR + GF   +  R  L +  P      +  PL  L L  K+ +       
Sbjct: 424 NLEQRRGRAGRVRPGFLSIVQSRP-LRETGPAHNSGDIPHPLHELALSIKL-LRLGPISG 251

Query: 858 FLSKAVDSPNIKAVDEAVILLQEIGVLDQREYLTTLGQRLAHISTDPRLAKAIVLAAIF 916
           FLS AV+ P I AV EA   L+ +  LD  + LT LG+ LA +  +P L K I+   IF
Sbjct: 250 FLSXAVEPPPIDAVVEAEATLRSMHALDSNDELTPLGRILARMPIEPHLGKMIIYGCIF 74
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|124248484|ref|NP_035988.2| odd Oz/ten-m homolog 4
[Mus musculus]
         (2796 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

28301                                                                 181   4e-45
37574                                                                  59   4e-18
25893                                                                  82   4e-15
31203                                                                  50   2e-05
07364                                                                  48   6e-05
00070                                                                  46   2e-04
06474                                                                  42   0.004
20856                                                                  39   0.004
14158                                                                  42   0.004
26039                                                                  41   0.008
14608                                                                  39   0.010
30893                                                                  39   0.022
09271                                                                  35   0.29 
09025                                                                  35   0.58 
14896                                                                  35   0.62 
03572                                                                  34   0.81 
12576                                                                  33   1.9  
12472                                                                  32   2.5  
07008                                                                  32   4.0  
08890                                                                  32   4.5  
25843                                                                  31   8.6  
>28301
          Length = 2767

 Score =  181 bits (459), Expect = 4e-45,   Method: Compositional matrix adjust.
 Identities = 129/436 (29%), Positives = 202/436 (46%), Gaps = 8/436 (1%)
 Frame = -2

Query: 2360 EITSLYYDLQGHLFAMELSSGDEFYIACDNIGTPLAVFSGTGLMIKQILYTAYGEIYMDT 2419
            E T  +YD    L AM+  SG  +YIA D   TPL VF   G ++KQ  YT  G   +DT
Sbjct: 2751 EATVFFYDTSNSLIAMQ-RSGKIYYIATDPSHTPLVVFDERGYVVKQCSYTPLGLRNLDT 2575

Query: 2420 NPNFQIIIGYHGGLYDPLTKLVHMGRRDYDVLAGRWTSPDH----ELWKRLSSNSIVPFH 2475
            +P+F +  G+ G +Y+   +L  M RR YDV  GR+ +PD+    +  KR+  +  +  +
Sbjct: 2574 DPDFDLPFGFQGAVYNEGVQLAFMERRVYDVHLGRFLTPDYAGAFDKLKRVMEDPEI-LN 2398

Query: 2476 LYMFKNNNPISN--SQDIKCFMTDVNSWLLTFGFQLHNVIPGYPKPDTDAMEPSYELVHT 2533
            LY ++   P+ N     ++    D+  WL   GF + ++ P      T  + P   + + 
Sbjct: 2397 LYQYR---PLVNLHLHQLQHPRMDLAEWLTVLGFDIGSIAPDVSY--TGDINPDLSMTNH 2233

Query: 2534 QMKTQEWDNSKSILGVQCEVQKQLKAFVTLERFDQLYGSTITSCQQAPETKKFASSGSIF 2593
            Q+ T       S    +C  ++ +   + +    +   S +T     P  +  +    IF
Sbjct: 2232 QLLT-------SSSAFECTFRRDMHNLLMMSAVPR---SKVTPLHHLP-AETASPLEPIF 2086

Query: 2594 GKGVKFALKDGRVTTDIISVANEDGRRIAAILNNAHYLENLHFTIDGVDTHYFVKPGPSE 2653
            G GV  +  +G+   +I  +A E  R++A +L N   + ++ FTI G D HYFV+   S+
Sbjct: 2085 GDGVTISNVNGKAMVNIADIAAEWSRKLATVLLNNSDIVDISFTIKGKDVHYFVRSDASK 1906

Query: 2654 GD--LAILGLSGGRRTLENGVNVTVSQINTVLSGRTRRYTDIQLQYRALCLNTRYGTTVD 2711
             D  L  LG+     T +NGVNV+V +         R   D+++      +N RYGTTV 
Sbjct: 1905 ADQGLRSLGIHSTLVTYDNGVNVSVHRTQR----GDRSEVDVRVHSNHTVINVRYGTTVQ 1738

Query: 2712 EEKVRVLELXXXXXXXXXXXXXXXXXXXXXXXXXAWTDGEKQQVLNTGRVQGYDGFFVTS 2771
             EK RVL                            WT  E  ++  TG+V GY G ++ +
Sbjct: 1737 HEKKRVLRHAFDRAVRHAWQREKHLLQHSLPSQHLWTQSEVLELAQTGQVSGYVGQYILT 1558

Query: 2772 VEQYPELSDSANNIHF 2787
             + YPEL+D  NNI F
Sbjct: 1557 PDHYPELADDCNNIRF 1510
>37574
          Length = 433

 Score = 58.9 bits (141), Expect(2) = 4e-18,   Method: Compositional matrix adjust.
 Identities = 31/62 (50%), Positives = 35/62 (56%)
 Frame = -3

Query: 776 GWMGAACDQRACHPRCAEHGTCRDGKCECSPGWNGEHCTIAHYLDRVVKEGCPGLCNGNG 835
           GW GA CDQ  C  RC  HG C +G C C  GWNG+HCTI          GCP  C+G+G
Sbjct: 170 GWTGALCDQLQCDRRCHAHGFCSNGSCVCDKGWNGKHCTI---------NGCPKDCSGHG 18

Query: 836 RC 837
            C
Sbjct: 17  EC 12

 Score = 53.1 bits (126), Expect(2) = 4e-18,   Method: Composition-based stats.
 Identities = 22/57 (38%), Positives = 30/57 (52%), Gaps = 5/57 (8%)
 Frame = -1

Query: 692 PTCSSRGVCVRGECHCSVGWGGTNCETPRA-----TCLDQCSGHGTFLPDTGLCNCD 743
           P CS +GVC+ G+C C  G+ G++C           C   CSGHG +  D G C C+
Sbjct: 433 PNCSGQGVCLHGQCRCFNGFKGSDCSLADKINVTLVCAKNCSGHGLYDLDLGTCRCE 263

 Score = 44.7 bits (104), Expect(2) = 2e-10,   Method: Composition-based stats.
 Identities = 24/55 (43%), Positives = 26/55 (47%), Gaps = 9/55 (16%)
 Frame = -1

Query: 596 NCYGNGDCISGTCHCFLGFLGPDCGRAS-------CPVLCSGNGQY--MKGRCLC 641
           NC G G C+ G C CF GF G DC  A        C   CSG+G Y    G C C
Sbjct: 430 NCSGQGVCLHGQCRCFNGFKGSDCSLADKINVTLVCAKNCSGHGLYDLDLGTCRC 266

 Score = 41.2 bits (95), Expect(2) = 2e-10,   Method: Compositional matrix adjust.
 Identities = 26/67 (38%), Positives = 33/67 (49%)
 Frame = -3

Query: 665 HGTCIMGTCICNPGYKGESCEEVDCMDPTCSSRGVCVRGECHCSVGWGGTNCETPRATCL 724
           HG C    C+C  G+ G  C+++ C D  C + G C  G C C  GW G +C      C 
Sbjct: 209 HGHCRNQRCVCAQGWTGALCDQLQC-DRRCHAHGFCSNGSCVCDKGWNGKHCTIN--GCP 39

Query: 725 DQCSGHG 731
             CSGHG
Sbjct: 38  KDCSGHG 18

 Score = 49.7 bits (117), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 34/89 (38%), Positives = 44/89 (49%)
 Frame = -3

Query: 614 FLGPDCGRASCPVLCSGNGQYMKGRCLCHSGWKGAECDVPTNQCIDVACSSHGTCIMGTC 673
           F GPDC    C ++C  +G     RC+C  GW GA CD       D  C +HG C  G+C
Sbjct: 257 FTGPDCETEVCRLVCV-HGHCRNQRCVCAQGWTGALCDQLQ---CDRRCHAHGFCSNGSC 90

Query: 674 ICNPGYKGESCEEVDCMDPTCSSRGVCVR 702
           +C+ G+ G+ C    C    CS  G C R
Sbjct: 89  VCDKGWNGKHCTINGC-PKDCSGHGECHR 6

 Score = 45.8 bits (107), Expect = 2e-04,   Method: Composition-based stats.
 Identities = 26/71 (36%), Positives = 31/71 (43%), Gaps = 5/71 (7%)
 Frame = -3

Query: 688 DCMDPTCSSRGVCVRGECH-----CSVGWGGTNCETPRATCLDQCSGHGTFLPDTGLCNC 742
           DC    C  R VCV G C      C+ GW G  C+  +  C  +C  HG      G C C
Sbjct: 245 DCETEVC--RLVCVHGHCRNQRCVCAQGWTGALCD--QLQCDRRCHAHG--FCSNGSCVC 84

Query: 743 DPSWTGHDCSI 753
           D  W G  C+I
Sbjct: 83  DKGWNGKHCTI 51

 Score = 41.6 bits (96), Expect(2) = 0.003,   Method: Composition-based stats.
 Identities = 20/58 (34%), Positives = 29/58 (50%)
 Frame = -1

Query: 789 PRCAEHGTCRDGKCECSPGWNGEHCTIAHYLDRVVKEGCPGLCNGNGRCTLDLNGWHC 846
           P C+  G C  G+C C  G+ G  C++A  ++  V   C   C+G+G   LDL    C
Sbjct: 433 PNCSGQGVCLHGQCRCFNGFKGSDCSLADKIN--VTLVCAKNCSGHGLYDLDLGTCRC 266

 Score = 19.6 bits (39), Expect(2) = 0.003,   Method: Compositional matrix adjust.
 Identities = 8/13 (61%), Positives = 8/13 (61%)
 Frame = -3

Query: 846 CVCQLGWRGTGCD 858
           CVC  GW G  CD
Sbjct: 185 CVCAQGWTGALCD 147

 Score = 39.3 bits (90), Expect = 0.025,   Method: Composition-based stats.
 Identities = 36/131 (27%), Positives = 53/131 (40%), Gaps = 6/131 (4%)
 Frame = -1

Query: 628 CSGNGQYMKGRCLCHSGWKGAECDVPTNQCIDVA----CSSHG--TCIMGTCICNPGYKG 681
           CSG G  + G+C C +G+KG++C +     + +     CS HG     +GTC C      
Sbjct: 427 CSGQGVCLHGQCRCFNGFKGSDCSLADKINVTLVCAKNCSGHGLYDLDLGTCRCERHSPA 248

Query: 682 ESCEEVDCMDPTCSSRGVCVRGECHCSVGWGGTNCETPRATCLDQCSGHGTFLPDTGLCN 741
           +   +       C+   V + G C   V  GG      RA C   CS  G      G+  
Sbjct: 247 QIARQRYVAWCVCTVT-VAISGAC---VHKGG------RALCATSCSVTG------GVTR 116

Query: 742 CDPSWTGHDCS 752
              + TG  C+
Sbjct: 115 TASAPTGRACA 83

 Score = 30.8 bits (68), Expect = 9.1,   Method: Compositional matrix adjust.
 Identities = 24/69 (34%), Positives = 31/69 (44%)
 Frame = -3

Query: 600 NGDCISGTCHCFLGFLGPDCGRASCPVLCSGNGQYMKGRCLCHSGWKGAECDVPTNQCID 659
           +G C +  C C  G+ G  C +  C   C  +G    G C+C  GW G  C +  N C  
Sbjct: 209 HGHCRNQRCVCAQGWTGALCDQLQCDRRCHAHGFCSNGSCVCDKGWNGKHCTI--NGCPK 36

Query: 660 VACSSHGTC 668
             CS HG C
Sbjct: 35  -DCSGHGEC 12
>25893
          Length = 437

 Score = 81.6 bits (200), Expect = 4e-15,   Method: Compositional matrix adjust.
 Identities = 41/120 (34%), Positives = 72/120 (60%), Gaps = 3/120 (2%)
 Frame = -2

Query: 1558 AKDAKLNTPSSLAVCADGELYVADLGNIRIRFIRKNKPFLNTQNMYELSSPIDQELYLFD 1617
            A  A  + P+S+ V  DG L++AD+GN+R+  I    P LN+++ YE+ SP  QE+Y+F+
Sbjct: 436  AAQALFSDPTSVTVTPDGVLHLADMGNLRVFSIISQLPTLNSRH-YEVVSPETQEIYVFN 260

Query: 1618 TSGKHLYTQSLPTGDYLYNFTY---TGDGDITHITDNNGNMVNVRRDSTGMPLWLVVPDG 1674
              G+H +T ++ T  Y+YNFTY   +  G +  + D+  N + ++RD   +   ++ P+ 
Sbjct: 259  YFGQHKHTINILTDQYMYNFTYKVFSSHGRLVAVEDSAANKIQIKRDYQDLAKTIIXPNN 80
>31203
          Length = 1813

 Score = 49.7 bits (117), Expect = 2e-05,   Method: Composition-based stats.
 Identities = 69/276 (25%), Positives = 94/276 (34%), Gaps = 58/276 (21%)
 Frame = -3

Query: 635 MKGRCLCHSGW--KGAECDVPT----NQCID-VACSSHGTCI--MGTCICNPGY---KGE 682
           M G C C+ G+     +C +P+    N C++ + C S+  C    GTC C   Y   KG 
Sbjct: 803 MGGLCECNDGFYIDNKKC-IPSIKVHNPCVETLQCVSNAVCTPETGTCECRDDYFPLKG- 630

Query: 683 SCEEVDCMDPTCSSRGVCVR---------GECHCSVGW------------------GGTN 715
           +CE+       C   G CV          G C C  G+                  G   
Sbjct: 629 NCEKKKKASEPCGGYGQCVDNAECNSPQGGLCLCHEGFFENDGACRTQTELGKACTGEEE 450

Query: 716 CETPRATCLDQCSGHGTFLPDTGLCNCDPSWTGHDCSIEIXXXXXXXXXXXXXXXXXXED 775
           C TP + C++ C     +  D GLC  +    G  CS +                   +D
Sbjct: 449 C-TPNSVCVETCRCREGYFKDKGLCY-EKKLVGDPCSFDDMCSLWMICSSEINGFCICQD 276

Query: 776 GWMGAACDQRACHPR------CAEHGTC---------RDGKCECSPGWNGE--HCTIAHY 818
           G+       R C  R      C E G C           G C+C P +  E   C     
Sbjct: 275 GFFE---QNRQCGGRIPPGEECQELGACVINAECSNPSGGICQCLPDFYREDKECKAL-- 111

Query: 819 LDRVVKEGC--PGLCNGNGRCTLDLNGWHCVCQLGW 852
             +   E C  P  C  N  CT D +   CVC  G+
Sbjct: 110 --KKPSEPCFAPKECVPNANCTEDFDALVCVCNAGF 9

 Score = 46.2 bits (108), Expect = 2e-04,   Method: Composition-based stats.
 Identities = 52/188 (27%), Positives = 75/188 (39%), Gaps = 34/188 (18%)
 Frame = -3

Query: 593  CPSNCYG-NGDC-----ISGTCHCFLGFLGPDCGRASCPVLCSGNGQYMKGRCLCHSGW- 645
            CPS+ Y  +G C     +  +C       G +CG+ S   LCS    +  G C C  G+ 
Sbjct: 1682 CPSDHYTRDGKCHGRKVVGESCK------GGECGQNS---LCS---NFFGGVCQCVPGFF 1539

Query: 646  -KGAEC---DVPTNQCI-DVACSSHGTCIMGTCICNPGYKGE--SCEEV-----DCMDPT 693
                +C   + P ++C  +  C  +  C MGTC C  GY  +   C  +      C DP+
Sbjct: 1538 EDNQQCVGVETPGSRCTGEGQCVLNAECTMGTCTCKSGYYQDLNKCSPLLKPDEQCTDPS 1359

Query: 694  -CSSRGVCVRGE------CHCSVGW--GGTNCET-----PRATCLDQCSGHG-TFLPDTG 738
             C     CV         C C  G+      CE       + T L QC+ +     P  G
Sbjct: 1358 QCVPDATCVVDVQRDIQICKCQTGFYKDKGKCEQLKDAGEKCTGLGQCNLNAECSTPYGG 1179

Query: 739  LCNCDPSW 746
            LC CD ++
Sbjct: 1178 LCTCDDTF 1155
>07364
          Length = 985

 Score = 47.8 bits (112), Expect = 6e-05,   Method: Compositional matrix adjust.
 Identities = 49/151 (32%), Positives = 69/151 (45%), Gaps = 3/151 (1%)
 Frame = -1

Query: 604 ISGTCHCFLGFLGPDCGRASCPVLCSGNGQYMK-GRCLCHSGWKGAECDVPTNQCIDVAC 662
           ++  C C  G+ G DC +  C   C   GQ ++  RC C  G+KG  C+ P        C
Sbjct: 880 MTAVCACPYGYTGVDC-QPYCHKTCHNGGQCIRHDRCRCAKGYKGRYCETPV---CGRGC 713

Query: 663 SSHGTCIMG-TCICNPGYKGESCEEVDCMDPTCSSRGVCVR-GECHCSVGWGGTNCETPR 720
            + G C+    C C  GY+G  C++  C  P+C + G C+  G C C     G  C   R
Sbjct: 712 VNGGKCVAPRRCSCPSGYRGRRCQKPRC-RPSCKNGGKCIAPGICLCPPSLLGPRCR--R 542

Query: 721 ATCLDQCSGHGTFLPDTGLCNCDPSWTGHDC 751
            TC  +C   G  + + G C C PS+ G  C
Sbjct: 541 HTCRKKCRNGGRCVAN-GKCLCPPSFYGRYC 452

 Score = 42.7 bits (99), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 67/222 (30%), Positives = 84/222 (37%), Gaps = 8/222 (3%)
 Frame = -1

Query: 603 CIS-GTCHCFLGFLGPDCGRASC--PVLCSGNGQY--MKGRCLCHSGWKGAECDVPTNQC 657
           C+S G CHC   F G  C    C  P L   NG Y  M   C C  G+ G +C    ++ 
Sbjct: 982 CVSPGLCHCPHNFTGLSCETPHCDPPCL---NGGYCTMTAVCACPYGYTGVDCQPYCHK- 815

Query: 658 IDVACSSHGTCIM-GTCICNPGYKGESCEEVDCMDPTCSSRGVCVRG-ECHCSVGWGGTN 715
               C + G CI    C C  GYKG  CE   C    C + G CV    C C  G+ G  
Sbjct: 814 ---TCHNGGQCIRHDRCRCAKGYKGRYCETPVCGR-GCVNGGKCVAPRRCSCPSGYRGRR 647

Query: 716 CETPRATCLDQCSGHGTFLPDTGLCNCDPSWTGHDCSIEIXXXXXXXXXXXXXXXXXXED 775
           C+ PR  C   C   G  +   G+C C PS                              
Sbjct: 646 CQKPR--CRPSCKNGGKCI-APGICLCPPS------------------------------ 566

Query: 776 GWMGAACDQRACHPRCAEHGTC-RDGKCECSPGWNGEHCTIA 816
             +G  C +  C  +C   G C  +GKC C P + G +C  A
Sbjct: 565 -LLGPRCRRHTCRKKCRNGGRCVANGKCLCPPSFYGRYCHRA 443
>00070
          Length = 1809

 Score = 46.2 bits (108), Expect = 2e-04,   Method: Composition-based stats.
 Identities = 30/107 (28%), Positives = 44/107 (41%), Gaps = 17/107 (15%)
 Frame = +1

Query: 638 RCLCHSGWKGAECDVPTNQ---CIDVACSSHGTCIMGT-----CICNPGYKGESCE---- 685
           +C C  G+ G  CD   +    C    C + G+C   +     C C   Y+G+SCE    
Sbjct: 217 KCTCAKGYSGETCDQSVDTSGACASRPCQNGGSCKPTSYGSFKCTCPALYQGDSCEIKSA 396

Query: 686 --EVDCMDPTCSSRG---VCVRGECHCSVGWGGTNCETPRATCLDQC 727
                C D   +  G   VC +G+C C+ G+   +      TCL  C
Sbjct: 397 WVNSPCGDTGVACTGANTVCFKGKCLCTPGY---HYSVSSQTCLKSC 528

 Score = 39.3 bits (90), Expect = 0.024,   Method: Composition-based stats.
 Identities = 30/111 (27%), Positives = 48/111 (43%), Gaps = 22/111 (19%)
 Frame = +1

Query: 608 CHCFLGFLGPDCGRA-----SCPVLCSGNG------QYMKGRCLCHSGWKGAECDVPT-- 654
           C C  G+ G  C ++     +C      NG       Y   +C C + ++G  C++ +  
Sbjct: 220 CTCAKGYSGETCDQSVDTSGACASRPCQNGGSCKPTSYGSFKCTCPALYQGDSCEIKSAW 399

Query: 655 --NQCID--VACSSHGT-CIMGTCICNPGY----KGESCEEVDCMDPTCSS 696
             + C D  VAC+   T C  G C+C PGY      ++C +  C  P+  S
Sbjct: 400 VNSPCGDTGVACTGANTVCFKGKCLCTPGYHYSVSSQTCLK-SCPKPSLQS 549

 Score = 37.0 bits (84), Expect = 0.10,   Method: Composition-based stats.
 Identities = 31/139 (22%), Positives = 47/139 (33%), Gaps = 2/139 (1%)
 Frame = +1

Query: 673 CICNPGYKGESCEEVDCMDPTCSSRGVCVRGECHCSVGWGGTNCETPRATCLDQCSGHGT 732
           C C  GY GE+C      D +  + G C    C       G +C+          + +G+
Sbjct: 220 CTCAKGYSGETC------DQSVDTSGACASRPCQ-----NGGSCKP---------TSYGS 339

Query: 733 FLPDTGLCNCDPSWTGHDCSIEIXXXXXXXXXXXXXXXXXXEDGWMGAACDQR--ACHPR 790
           F      C C   + G  C I                    +  W+ + C     AC   
Sbjct: 340 F-----KCTCPALYQGDSCEI--------------------KSAWVNSPCGDTGVAC--- 435

Query: 791 CAEHGTCRDGKCECSPGWN 809
              +  C  GKC C+PG++
Sbjct: 436 TGANTVCFKGKCLCTPGYH 492
>06474
          Length = 2466

 Score = 41.6 bits (96), Expect = 0.004,   Method: Composition-based stats.
 Identities = 34/140 (24%), Positives = 52/140 (37%), Gaps = 26/140 (18%)
 Frame = -1

Query: 637  GRCLCHSGWKGAECDVPTNQC---IDVACSSHGTCIM---------GTCICNPGYKGESC 684
            G C C S    A+ D    QC   I VAC++   C+          GTC C    K  + 
Sbjct: 2073 GTCTCTSASYTAKSD--NTQCLSLIGVACTTDNPCVTTAETCTAGSGTCSC-ASTKATTY 1903

Query: 685  EEVDCMD---------PTCSSRGVCVRGECHCSVGWGGTNCETPRATCLDQCSGHGTFLP 735
            ++ +C+D          TC + G C    C C+ G+  +         +D      +  P
Sbjct: 1902 DKTECVDKVGDACSSAATCPTNGACTSSLCACASGFTASTDNKQCVKLIDAACSSNSECP 1723

Query: 736  -----DTGLCNCDPSWTGHD 750
                  +  C+CD  +T  D
Sbjct: 1722 LNAQCTSSTCSCDTGYTSDD 1663

 Score = 37.0 bits (84), Expect = 0.11,   Method: Composition-based stats.
 Identities = 27/96 (28%), Positives = 38/96 (39%), Gaps = 18/96 (18%)
 Frame = -1

Query: 605  SGTCHCF------------LGFLGPDCGRASCPVLCSGNGQYMKGRCLCHSGWKGAECDV 652
            SGTC C             +  +G  C  A+    C  NG      C C SG+  +  + 
Sbjct: 1944 SGTCSCASTKATTYDKTECVDKVGDACSSAAT---CPTNGACTSSLCACASGFTASTDNK 1774

Query: 653  PTNQCIDVACSSHGTCIM------GTCICNPGYKGE 682
               + ID ACSS+  C +       TC C+ GY  +
Sbjct: 1773 QCVKLIDAACSSNSECPLNAQCTSSTCSCDTGYTSD 1666
>20856
          Length = 434

 Score = 39.3 bits (90), Expect(2) = 0.004,   Method: Compositional matrix adjust.
 Identities = 23/91 (25%), Positives = 48/91 (52%), Gaps = 2/91 (2%)
 Frame = +1

Query: 2100 EEGMVNARFDYNYDNSFRVTSMQAVI-NETPLPIDLYRYDDVSGKTEQFGKFGVIY-YDI 2157
            +  ++ A   ++YDN+FR+ S   V+ N   +  +L  ++D +G+ +Q     V +    
Sbjct: 85   DHRLLGASMTFDYDNNFRLISSSVVLSNNITMNYNL-SFNDRTGQLKQLSNLQVSWPSPD 261

Query: 2158 NQIITTAVMTHTKHFDAYGRMKEVQYEIFRS 2188
            NQ  +   +  T+ +D Y R+ +V+Y + R+
Sbjct: 262  NQTFSNGFVLITREYDGYRRLADVKYGLGRA 354

 Score = 21.6 bits (44), Expect(2) = 0.004,   Method: Composition-based stats.
 Identities = 7/25 (28%), Positives = 15/25 (60%)
 Frame = +3

Query: 2187 RSLMYWMTVQYDNMGRVVKKELKVG 2211
            +S+ + + + YD  GRV +   ++G
Sbjct: 348  KSVRFMLQINYDQTGRVHQWRRRIG 422
>14158
          Length = 668

 Score = 41.6 bits (96), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 43/147 (29%), Positives = 63/147 (42%), Gaps = 21/147 (14%)
 Frame = +3

Query: 630 GNGQYMKGRCLCHSGWKGAECDVPTNQCIDVACSSHGTCIMG-------TCIC-NPGYKG 681
           G G Y    C+C  G+ G  C+ P N C + +C+++ TC +         C C +  Y G
Sbjct: 18  GVGSYT---CVCPPGFNGTRCETPYNACDNNSCANNSTCTVNPDVSRGYVCDCADSNYSG 188

Query: 682 ESC----EEVDCMDPTCSSRGVCVRG-----ECHCSVGWGGTNCETPRATCLDQCSGHGT 732
           + C    E   C D  C + G C         C C+ G+ G+ CE+P   C+D    +GT
Sbjct: 189 DLCNINIENKSCADGLCQNPGSCTDDVNASFTCACAPGYTGSLCESPINYCVDLPCNNGT 368

Query: 733 FLPDTGL----CNCDPSWTGHDCSIEI 755
              +  L    C C   +TG  C   I
Sbjct: 369 CQSNASLQNFTCECVEGFTGDVCDANI 449
>26039
          Length = 441

 Score = 40.8 bits (94), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 39/122 (31%), Positives = 49/122 (40%), Gaps = 11/122 (9%)
 Frame = -1

Query: 637 GRCLCHSGWKGAECDVPTN------QCI-DVACSSHGTC--IMGTCICNPGYKGESCEEV 687
           GRC+C  GW G  C           +C  + +CS HG C  + G CIC  GY+G +C + 
Sbjct: 375 GRCICKPGWTGMRCSEHCRPGTFGAECKHNCSCSQHGECDPVTGACICQRGYRGTTCNQT 196

Query: 688 DCMDPTCSSRGVCVRGECHCSVGWGGTNCETPRATCLDQCSGHGTFLPD--TGLCNCDPS 745
                              C  GW G  C   R  CL  C  H T   D  TG+C C   
Sbjct: 195 -------------------CQAGWYGIGC---RHQCL--CEEHNTVSCDHVTGVCTCKHL 88

Query: 746 WT 747
           +T
Sbjct: 87  YT 82

 Score = 31.2 bits (69), Expect = 6.7,   Method: Compositional matrix adjust.
 Identities = 24/68 (35%), Positives = 34/68 (50%), Gaps = 4/68 (5%)
 Frame = -1

Query: 799 DGKCECSPGWNG----EHCTIAHYLDRVVKEGCPGLCNGNGRCTLDLNGWHCVCQLGWRG 854
           +G+C C PGW G    EHC    +     K  C   C+ +G C  D     C+CQ G+RG
Sbjct: 378 NGRCICKPGWTGMRCSEHCRPGTFGAE-CKHNCS--CSQHGEC--DPVTGACICQRGYRG 214

Query: 855 TGCDTSME 862
           T C+ + +
Sbjct: 213 TTCNQTCQ 190
>14608
          Length = 642

 Score = 38.9 bits (89), Expect(2) = 0.010,   Method: Compositional matrix adjust.
 Identities = 30/81 (37%), Positives = 37/81 (45%), Gaps = 9/81 (11%)
 Frame = +1

Query: 626 VLCSG--NGQYMKGRCLCHSGWKGAECDVPTNQCIDVA-----CSSHGTCIMGTCICNP- 677
            LC G  +G+   G C C  GWKG  CD  T+    +A     C+  G C  G C CN  
Sbjct: 220 ALCGGPSHGRCECGECDCLEGWKGEACDCSTDNSTCIASNGEICNDKGWCNCGRCKCNET 399

Query: 678 -GYKGESCEEVDCMDPTCSSR 697
             Y G +CEE     P C S+
Sbjct: 400 LDYMGPTCEEC----PDCPSK 450

 Score = 20.4 bits (41), Expect(2) = 0.010,   Method: Composition-based stats.
 Identities = 7/18 (38%), Positives = 11/18 (61%)
 Frame = +2

Query: 597 CYGNGDCISGTCHCFLGF 614
           C G+G+C+ G    F G+
Sbjct: 86  CSGHGECVCGEV*MFHGW 139
>30893
          Length = 490

 Score = 39.3 bits (90), Expect = 0.022,   Method: Compositional matrix adjust.
 Identities = 34/96 (35%), Positives = 49/96 (51%), Gaps = 10/96 (10%)
 Frame = +2

Query: 639 CLCHSGWKGAECDVPTNQCIDVACSSHGTC--IMG--TCICNPGYKGESCE-EVD-CMDP 692
           C C SG++G+ C+   N+C    C +  TC  ++G  TC C PGY+G +CE ++D C + 
Sbjct: 152 CTCASGFEGSYCENDINECFSAPCQNGATCTDLIGRYTCTCEPGYQGLNCEYDIDECHNQ 331

Query: 693 TCSSRGVC----VRGECHCSVGWGGTNCETPRATCL 724
            C + G C       +C C  G  G  CE     CL
Sbjct: 332 PCLNGGTCHDLVNTYKCSCPPGTQGLLCEMDENDCL 439

 Score = 37.4 bits (85), Expect = 0.093,   Method: Compositional matrix adjust.
 Identities = 45/140 (32%), Positives = 57/140 (40%), Gaps = 23/140 (16%)
 Frame = +2

Query: 638 RCLCHSGWKGAECDVPTNQCIDVA----------CSSHGTC----IMGTCICNPGYKGES 683
           RC C  GW GA CDV +  C   A          C + GTC        C C  G++G  
Sbjct: 5   RCNCSQGWTGALCDVQSVSCSVAASVRGVSEQDLCQNGGTCHNTGNTHMCTCASGFEGSY 184

Query: 684 CEE--VDCMDPTCSSRGVCV----RGECHCSVGWGGTNCETPRATCLDQ-CSGHGTF--L 734
           CE    +C    C +   C     R  C C  G+ G NCE     C +Q C   GT   L
Sbjct: 185 CENDINECFSAPCQNGATCTDLIGRYTCTCEPGYQGLNCEYDIDECHNQPCLNGGTCHDL 364

Query: 735 PDTGLCNCDPSWTGHDCSIE 754
            +T  C+C P   G  C ++
Sbjct: 365 VNTYKCSCPPGTQGLLCEMD 424
>09271
          Length = 1047

 Score = 35.4 bits (80), Expect = 0.29,   Method: Compositional matrix adjust.
 Identities = 24/65 (36%), Positives = 31/65 (47%), Gaps = 5/65 (7%)
 Frame = -2

Query: 658 IDVACSSHGTCIM-GTCICNPGYKGESCEEV---DCMDPTCSSRGVCVRG-ECHCSVGWG 712
              AC + G C+    C C PGY+G  C+     DC  P CS+ G C+ G  C C  G  
Sbjct: 953 CQPACLNGGQCVAYNRCRCPPGYRGRRCQHAFRPDCRPP-CSNGGTCLHGNRCQCPEGTS 777

Query: 713 GTNCE 717
           G  C+
Sbjct: 776 GHRCQ 762
>09025
          Length = 1044

 Score = 34.7 bits (78), Expect = 0.58,   Method: Composition-based stats.
 Identities = 26/72 (36%), Positives = 27/72 (37%), Gaps = 3/72 (4%)
 Frame = -1

Query: 597 CY---GNGDCISGTCHCFLGFLGPDCGRASCPVLCSGNGQYMKGRCLCHSGWKGAECDVP 653
           CY   G  DC SG C C  G     CG   C    SG     K   LCH  W        
Sbjct: 951 CYCQSGLCDCQSGLCDCQCGLCDCQCGLCDCQ---SGLCYCQKLWVLCH--WDNGHAK*K 787

Query: 654 TNQCIDVACSSH 665
           TN C D A + H
Sbjct: 786 TNCCSDSARTDH 751
>14896
          Length = 576

 Score = 34.7 bits (78), Expect = 0.62,   Method: Composition-based stats.
 Identities = 27/92 (29%), Positives = 37/92 (40%), Gaps = 7/92 (7%)
 Frame = +2

Query: 641 CHSGWKGAECDVPTNQC--IDVACSSHGTCIMGTCICNPGYKGESCEEVDCMDPTCSSRG 698
           C S   G  C  P+ +   I  +C++H        +C PG K    + V C+ P C  + 
Sbjct: 209 CASFCGGRSCQTPSFKPDPISPSCATH--------VCEPGQKC-VXQXVXCLIPPCPVQP 361

Query: 699 VCV-----RGECHCSVGWGGTNCETPRATCLD 725
           VCV      G C    G  GT    P   CL+
Sbjct: 362 VCVPIVIRPGTCPKPSGMAGTCVFRPGVNCLE 457
>03572
          Length = 776

 Score = 34.3 bits (77), Expect = 0.81,   Method: Composition-based stats.
 Identities = 16/42 (38%), Positives = 24/42 (57%)
 Frame = -1

Query: 1560 DAKLNTPSSLAVCADGELYVADLGNIRIRFIRKNKPFLNTQN 1601
            + + N P+ +AV  +G + VAD GN RI+    N  FL+  N
Sbjct: 353  NGQFNAPTGVAVDPNGHILVADWGNSRIQVFDANGSFLSYVN 228
>12576
          Length = 1682

 Score = 32.7 bits (73), Expect = 1.9,   Method: Compositional matrix adjust.
 Identities = 58/225 (25%), Positives = 81/225 (36%), Gaps = 23/225 (10%)
 Frame = -1

Query: 607 TCHCFLGFLGPDCGRASCPVLCSG----NGQYMK---------GRCLCHSGWKGAECDVP 653
           +C C  G+ G DC + + P  CS     NG   K           C+C  G+ GA C   
Sbjct: 998 SCXCINGYTGXDCSQTADP--CSSKPCKNGGMCKNVVQNGALVAACVCAPGFTGATCSQE 825

Query: 654 TNQCIDVACSSHGTC--------IMGTCICNPGYKGESCEE-VDCMDPTCSSRGVCVRGE 704
            N C    C +  TC            C C  GY GE+C++ VD            + G 
Sbjct: 824 NNPCSSRPCKNGATCSPQLTRSSATFKCXCKSGYSGETCDQKVD------------LSGA 681

Query: 705 CHCSVGWGGTNCETPRATCLDQCSGHGTFLPDTGLCNCDPSWTGHDCSIEIXXXXXXXXX 764
           C  S    G +C+ P A        +G++      C C   + G +C I+          
Sbjct: 680 CKSSPCLNGASCK-PTA--------YGSYK-----CACPALYQGDNCEIKSE-------- 567

Query: 765 XXXXXXXXXEDGWMGAACDQRA-CHPRCAEHGTCRDGKCECSPGW 808
                       W+ A C   A C     E+  C  GKC C+PG+
Sbjct: 566 ------------WVNAPCGBTAGCT---GENTVCFKGKCLCTPGY 477
>12472
          Length = 844

 Score = 32.3 bits (72), Expect = 2.5,   Method: Composition-based stats.
 Identities = 38/151 (25%), Positives = 51/151 (33%), Gaps = 26/151 (17%)
 Frame = +2

Query: 605 SGTCHC-------------FLGFLGPDCGRASCPVLCSGNGQYMKGRCLCHSGWKGAECD 651
           SGTC C              L  +G  C      V  +       G C C SG   ++ +
Sbjct: 11  SGTCACETTTHVAKXDNTQCLALIGQPCTTTHPCVXTADTCTAGSGTCSCASGKVASDDN 190

Query: 652 VPTNQCIDVACSSHGTCIMGT-----CICNPGYKGESCEE--VDCMDPTCSSR------G 698
                 I  ACS+   C         C CN G+   S  +  V  +   CS+       G
Sbjct: 191 KLCVILIGSACSATSDCPTNAACSTBCGCNSGFTASSDNKQCVKKITEACSABSECPIFG 370

Query: 699 VCVRGECHCSVGWGGTNCETPRATCLDQCSG 729
           VC    C CS G+   +  T       +CSG
Sbjct: 371 VCTSSICACSTGYTANSDNT-------KCSG 442
>07008
          Length = 1270

 Score = 32.0 bits (71), Expect = 4.0,   Method: Composition-based stats.
 Identities = 21/68 (30%), Positives = 28/68 (41%), Gaps = 7/68 (10%)
 Frame = -3

Query: 689  CMDPTCSSRGVCVRGECHCSVGWGGTN--CETPRATCLDQC-----SGHGTFLPDTGLCN 741
            C    C S+G C    C C+V W      C  P  T L+ C     + H   LP+  +C 
Sbjct: 1217 CHKLCCRSQGSCQGPWCPCAV-WKAVTACCWMPALTALEICVNLLLAKHQE-LPEQAVCQ 1044

Query: 742  CDPSWTGH 749
            C  S+  H
Sbjct: 1043 CSNSYIPH 1020
>08890
          Length = 1280

 Score = 31.6 bits (70), Expect = 4.5,   Method: Composition-based stats.
 Identities = 27/108 (25%), Positives = 36/108 (33%), Gaps = 16/108 (14%)
 Frame = +1

Query: 619 CGRASCPVLCSGNGQYMKGRC-LCHSGWKGA----------ECDVPTNQCIDVACSSHGT 667
           C ++ CP L       MK +C  C    KG+          E D   + C  V C     
Sbjct: 400 CEKSRCPELHYCGRAVMKDQCGCCDVCSKGSRFYGNALMRDEEDTRGSACAKVKCPKFKV 579

Query: 668 CI-----MGTCICNPGYKGESCEEVDCMDPTCSSRGVCVRGECHCSVG 710
           CI     +  C C   +    C+      P C S GV     CH  + 
Sbjct: 580 CIENMQGLPLCTCPSTF---ICKRRSRQRPVCGSDGVTYETRCHLRIA 714
>25843
          Length = 426

 Score = 30.8 bits (68), Expect = 8.6,   Method: Compositional matrix adjust.
 Identities = 18/48 (37%), Positives = 24/48 (50%), Gaps = 2/48 (4%)
 Frame = -3

Query: 707 CSVGWGGTNCETPRATCLDQCSGHGTFLPDTGLC--NCDPSWTGHDCS 752
           CS GW G NCE P       C G+ T   D G+C  +C+  + G  C+
Sbjct: 367 CSSGWHGRNCENP----CGNCKGNNTCRHDNGVCEQDCEDDYIGVLCT 236
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6755560|ref|NP_035533.1| solute carrier family 4
(anion exchanger), member 1 [Mus musculus]
         (929 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

14939                                                                 107   4e-45
17976                                                                 103   3e-22
18083                                                                  74   2e-13
>14939
          Length = 1186

 Score =  107 bits (267), Expect(2) = 4e-45,   Method: Compositional matrix adjust.
 Identities = 61/152 (40%), Positives = 84/152 (55%)
 Frame = -1

Query: 615  FPGKLRRVIGDFGVPISILIMVLVDSFIKGTYTQKLSVPDGLKVSNSSARGWVIHPLGLY 674
            FP  +R  + DF V I+IL MV+ D  + G  T KL VP+    +N   RGW+I+P+G  
Sbjct: 1114 FPTMVRATLSDFSVLIAILSMVVFDICV-GLPTPKLHVPETFAPTNPK-RGWLINPVGEN 941

Query: 675  RLFPTWMMFASVLPALLVFILIFLESQITTLIVSKPERKMIKGSGFHLDXXXXXXXXXXX 734
               P W   A+V+PALL  ILIF++ QIT +IV++ E K++KG G+HLD           
Sbjct: 940  ---PWWTTLAAVIPALLAVILIFMDQQITAVIVNRKENKLVKGRGYHLDLFIVSVLIILC 770

Query: 735  XXXXXPWLSATTVRSVTHANALTVMGKASGPG 766
                 PW  A TV S+ H N+L    + S P 
Sbjct: 769  SFLGLPWFVAATVLSINHVNSLKKESQCSAPA 674

 Score = 93.6 bits (231), Expect(2) = 4e-45,   Method: Compositional matrix adjust.
 Identities = 50/116 (43%), Positives = 68/116 (58%), Gaps = 1/116 (0%)
 Frame = -3

Query: 765 PGAAAQIQEVKEQRXXXXXXXXXXXXXXXMEPILSRIPLAVLFGIFLYMGVTSLSGIQLF 824
           PG   +   V+EQR               +  +L  IP+ VL+G+FLYMGV+SL G+QL 
Sbjct: 680 PGEQPKFLGVREQRVTGITIFLLIGISVMLTSVLKFIPMPVLYGVFLYMGVSSLRGMQLV 501

Query: 825 DRILLLFKPPKYHPDVPFVKRVKTWRMHLFTGIQIICLAVLWVVKS-TPASLALPF 879
            R+L+ F P KY  D+ F++ V+T R+HLFT IQI CL  LW +KS    S+A P 
Sbjct: 500 HRVLIWFMPAKYQWDLMFLRHVRTNRVHLFTIIQIFCLLCLWGIKSYKKISIAFPI 333
>17976
          Length = 781

 Score =  103 bits (257), Expect = 3e-22,   Method: Compositional matrix adjust.
 Identities = 46/100 (46%), Positives = 64/100 (64%)
 Frame = +1

Query: 774 VKEQRXXXXXXXXXXXXXXXMEPILSRIPLAVLFGIFLYMGVTSLSGIQLFDRILLLFKP 833
           V+EQR                  +L  IP+AVL+G+FLYMG+ +L G+Q  DRILL+ KP
Sbjct: 142 VREQRLTGLMVGLLSGLTVLFTAVLKFIPMAVLYGVFLYMGMAALKGMQFIDRILLMLKP 321

Query: 834 PKYHPDVPFVKRVKTWRMHLFTGIQIICLAVLWVVKSTPA 873
            KY PD  +++ V   R+H+FT IQ++CLAVLWV+KS  +
Sbjct: 322 AKYQPDTTYLRHVPIKRVHIFTAIQVVCLAVLWVIKSVKS 441
>18083
          Length = 865

 Score = 74.3 bits (181), Expect = 2e-13,   Method: Compositional matrix adjust.
 Identities = 44/163 (26%), Positives = 75/163 (46%), Gaps = 1/163 (0%)
 Frame = -3

Query: 694 ILIFLESQITTLIVSKPERKMIKGSGFHLDXXXXXXXXXXXXXXXXPWLSATTVRSVTHA 753
           +L F++  I+  +V+ P+ KM KG+ +H D                P + A    S  H 
Sbjct: 863 LLFFMDQNISAALVNAPQNKMKKGTAYHWDLLVIAVVNAVISVFAFPMVHAALPHSPLHV 684

Query: 754 NALTVMGKASGPGAAAQ-IQEVKEQRXXXXXXXXXXXXXXXMEPILSRIPLAVLFGIFLY 812
            AL  + +    G   Q +  V+E R               +  +L+ IP  VL+G+FLY
Sbjct: 683 RALADVEERVVQGHITQTVVRVRETRITAILSHILIGLSILIMFVLAYIPTPVLYGLFLY 504

Query: 813 MGVTSLSGIQLFDRILLLFKPPKYHPDVPFVKRVKTWRMHLFT 855
           + +T+L   Q+F+RI L F     +P   +++ V   ++H+FT
Sbjct: 503 VAITALYDNQMFERITLFFTEQSAYPPTHYIRHVPQRKVHIFT 375
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|86990450|ref|NP_034993.2| myosin IB [Mus musculus]
         (1107 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

25922                                                                 179   5e-45
28295                                                                 116   5e-26
01284                                                                  66   7e-11
19734                                                                  60   5e-09
30477                                                                  30   6.3  
>25922
          Length = 422

 Score =  179 bits (454), Expect = 5e-45,   Method: Compositional matrix adjust.
 Identities = 85/136 (62%), Positives = 103/136 (75%)
 Frame = -2

Query: 320 LERAFSFRTVEAKQEKVSTTLNVAQAYYARDALAKNLYSRLFSWLVNRINESIKAQTKVR 379
           L  A   RTV  K + V+T L+V+++ YARDAL K LYSR+FSWLV+RIN+SIK +   R
Sbjct: 409 LAHALMHRTVAVKGDMVTTDLSVSESSYARDALCKALYSRMFSWLVHRINDSIKVRGAQR 230

Query: 380 KKVMGVLDIYGFEIFEDNSFEQFIINYCNEKLQQIFIELTLKXXXXXXXXXXXXWTHIDY 439
            KVMGVLDIYGFE+FE+NSFEQFIINYCNEKLQQIFIELTLK            W H++Y
Sbjct: 229 TKVMGVLDIYGFEVFENNSFEQFIINYCNEKLQQIFIELTLKEEQEEYIKEGIEWIHVEY 50

Query: 440 FNNAIICDLIENNTNG 455
           FNNA+IC+LIE + +G
Sbjct: 49  FNNAVICELIEKSVSG 2
>28295
          Length = 502

 Score =  116 bits (291), Expect = 5e-26,   Method: Compositional matrix adjust.
 Identities = 66/165 (40%), Positives = 93/165 (56%)
 Frame = -3

Query: 763 GWKARKILRELKHQKRCKEAATTIAAYWHGTQXXXXXXXXXXXXXXXHAVAVIWAYWLGL 822
           G+KAR +L +LK +KR  EAA  I  Y    Q                A  VI  Y+ G 
Sbjct: 494 GYKARVLLAQLKEEKRRDEAAVVIQKYARALQARALLGRMKREKLEQWAQGVIVKYFHGW 315

Query: 823 KVRREYRKFFRANAGKKIYEFTLQRIVQKYLLEMKNKMPSLSPIDKNWPSRPYLFLDSTH 882
           +VR+ Y+  FR  AG K+  F    + ++YLL++++ +PS+SP    WP+ P  F ++T 
Sbjct: 314 QVRKVYKPKFRRIAGPKVARFIKTALKRRYLLKLRDSLPSMSPTSAAWPAAPSRF-NATS 138

Query: 883 KELKRIFHLWRCKKYRDQFTDQQKLIYEEKLEASELFKDKKALYP 927
           +ELK +FH WRC KYR +F  + +    EKL AS+LFKDKK  YP
Sbjct: 137 QELKTLFHRWRCAKYRQRFDSKAQHRMREKLTASDLFKDKKDTYP 3
>01284
          Length = 1603

 Score = 66.2 bits (160), Expect = 7e-11,   Method: Compositional matrix adjust.
 Identities = 43/153 (28%), Positives = 77/153 (50%), Gaps = 1/153 (0%)
 Frame = +2

Query: 569 TAGSQFKASVATLMRNLQTKNPNYIRCIKPNDKKAAHIFNESLVCHQIRYLGLLENVRVR 628
           + G++F+  +  LM  L++   N+IRCIKPN K   H+F  + +  Q++  G++  + + 
Sbjct: 17  SVGTKFRKQLLVLMDKLKSTGTNFIRCIKPNVKMVDHLFEGANILSQLQCAGMVSVLELM 196

Query: 629 RAGYAFRQAYEPCLERYKMLCKQTWPHW-KGPARSGVEVLFNELEIPVEEHSFGRSKIFI 687
           + G+  R    P  E Y M  K   P   +   R   + LF  L +  ++  FG +K+F 
Sbjct: 197 QQGFPSR---TPFSELYNMYKKYLPPELSRLDPRLFCKSLFKALGLDDKDFKFGLTKVFF 367

Query: 688 RNPRTLFQLEDLRKQRLEDLATLIQKIYRGWKC 720
           R P    + + + K   E+LA L++K+ +   C
Sbjct: 368 R-PGKFAEFDQIMKSDPENLAELVKKVKKWLLC 463
>19734
          Length = 427

 Score = 60.1 bits (144), Expect = 5e-09,   Method: Compositional matrix adjust.
 Identities = 39/111 (35%), Positives = 58/111 (52%), Gaps = 5/111 (4%)
 Frame = +2

Query: 996  IKSEVPLVDVTKVSMSSQNDGFFAVHL---KEGSEAASKGDFLFSSDHLIEMATKLYRTT 1052
            +K  +PL  VTK+S S   D     HL   + G   A KGDF+FS+D+LIE+  K+    
Sbjct: 5    LKYRIPLSLVTKISTSPYKDKLLVFHLHKQENGDMLAKKGDFVFSNDNLIEIVAKVVMAI 184

Query: 1053 LSQTKQKLNIEISDEFLVQFRQDKVCVKFIQGNQ--KNGSVPTCKRKNNRL 1101
             + T ++  + +S   L +F+   V V F  G    ++G+V    RK NRL
Sbjct: 185  QTLTGKQPEVHVSPRMLAEFKGHTVEVSFKNGQPEVQSGNV-RITRKGNRL 334
>30477
          Length = 916

 Score = 29.6 bits (65), Expect = 6.3,   Method: Compositional matrix adjust.
 Identities = 23/85 (27%), Positives = 39/85 (45%), Gaps = 6/85 (7%)
 Frame = -3

Query: 641 CLERYKMLCKQTWPH--WKGPARSGVEVLFNELEI-PVEEHSFGRSKIFIRNPRTL---F 694
           CL+   ++ K   P   W+       E  +N +   PV+E     S   IRN   L   +
Sbjct: 362 CLQVQSVITKLLGPFSGWESKLTVARESGYNMIHFTPVQELGISNSAYSIRNQLVLSPVY 183

Query: 695 QLEDLRKQRLEDLATLIQKIYRGWK 719
              +  +  L+DLA L++K++R W+
Sbjct: 182 SQGEKSQYSLKDLAELVRKMHREWR 108
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|119392070|ref|NP_796355.2| component of oligomeric
golgi complex 3 [Mus musculus]
         (828 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

36676                                                                 178   8e-45
22747                                                                  30   2.7  
16311                                                                  29   9.0  
17572                                                                  29   9.7  
>36676
          Length = 761

 Score =  178 bits (452), Expect = 8e-45,   Method: Compositional matrix adjust.
 Identities = 100/221 (45%), Positives = 127/221 (57%), Gaps = 2/221 (0%)
 Frame = +1

Query: 134 LSGFQEQCDAILNDVNSALQHQESLQKQYLFVSNKTGTLHEACEQLLKEQSELADLAEHI 193
           LSG    C      V   + +   L +QY+ VS KT  LH+ CE LL EQ+ L ++AE +
Sbjct: 115 LSGAVRHCA---RGVTQCVDYLRQLHQQYINVSTKTNALHDECEHLLAEQTRLMNMAESV 285

Query: 194 QQKLSYFNELETINTKLNSPTLSVNSEGFIPMLAKLDDCITYISSHPNFKDYPVYLLKFK 253
             KLSYFNE +TI TKL+   LSV +E   P         T    +P FK+  +YL +F 
Sbjct: 286 SNKLSYFNEYDTITTKLSRQALSVTNESLFPCCLAWTSVSTT*GQNPRFKESEIYLARFS 465

Query: 254 QCLSKALHLMKTYXXXXXXXXXXXXX-KRDPSSVPN-ADNAFTLFYVKFRAAAPKVRTLI 311
           QCLS+AL  +KTY              K+D    PN +DNAFTLFY KFRA AP+V+ L 
Sbjct: 466 QCLSQALSHIKTYVSNILTSATQQVQPKKD---APNMSDNAFTLFYGKFRANAPRVKPLT 636

Query: 312 EQIEQRSEKIPEYQHLLNDIHQCYLDQRELLLGPSIAYTVT 352
           EQ+E R EK PEY  +L D+H CY  QR+LLL PSI  T+T
Sbjct: 637 EQLELRLEKGPEYHQVLTDLHMCYFTQRQLLLTPSITTTIT 759

 Score = 56.2 bits (134), Expect = 5e-08,   Method: Compositional matrix adjust.
 Identities = 24/48 (50%), Positives = 35/48 (72%)
 Frame = +2

Query: 100 ERIETAQQFFSWFAKLQTQMDQDEGTKYRQMRDYLSGFQEQCDAILND 147
           ++IE AQQFFSWF++L+  ++Q E  +YR   D L G+QEQCD +L +
Sbjct: 5   QKIENAQQFFSWFSQLEDSIEQGEEEQYRPYLDSLRGYQEQCDTVLGE 148
>22747
          Length = 720

 Score = 30.4 bits (67), Expect = 2.7,   Method: Composition-based stats.
 Identities = 25/90 (27%), Positives = 34/90 (37%), Gaps = 15/90 (16%)
 Frame = +3

Query: 498 IAQSLKDEQKKAPSEASFSD---------------VRLEEGEASGLRKSGSTDSLNPRPQ 542
           I  S  +EQK  P ++   D               + + E   SGL       +LN    
Sbjct: 12  ITNSSSNEQKSIPWDSLLPDSTV*CKVAHFVLNSLLTV*EQHCSGLNMLKPFSNLNKGLC 191

Query: 543 TTISPADLHGMWYPTVRRTLVCLSKLYRCI 572
             ISP  LHG W P+V      L K + C+
Sbjct: 192 PWISPGGLHGPWIPSVFSGKPHLXKYHACL 281
>16311
          Length = 584

 Score = 28.9 bits (63), Expect = 9.0,   Method: Compositional matrix adjust.
 Identities = 15/40 (37%), Positives = 23/40 (57%)
 Frame = -2

Query: 432 NEVLEDHVQHNAEQLGAFAAGVKQMLEDVQERLVYRTHIY 471
           N+ LEDH Q +AEQ   F   +  ML DV+ ++   T ++
Sbjct: 454 NDKLEDHEQTDAEQ-SMFKKMLNPMLSDVESKVSASTQMF 338
>17572
          Length = 860

 Score = 28.9 bits (63), Expect = 9.7,   Method: Compositional matrix adjust.
 Identities = 19/50 (38%), Positives = 26/50 (52%), Gaps = 1/50 (2%)
 Frame = -1

Query: 341 LLLGPSIAYTVTELTSQNNRDHCALVRSGCA-FMVHVCQDEHQLYNEFFT 389
             L PS     T LTS +   HC L R GC  F V + Q+ +  +++FFT
Sbjct: 368 FYLPPSFHQNKTALTSHHT--HCVLARIGCCKFFVQI-QNTNVDFSQFFT 228
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|19923070|ref|NP_598879.1| glycoprotein, synaptic 2
isoform 1 [Mus musculus]
         (308 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

30370                                                                 176   1e-44
32229                                                                  31   0.78 
03675                                                                  29   1.9  
06288                                                                  28   4.9  
01498                                                                  28   5.7  
>30370
          Length = 399

 Score =  176 bits (445), Expect = 1e-44,   Method: Compositional matrix adjust.
 Identities = 80/133 (60%), Positives = 99/133 (74%), Gaps = 1/133 (0%)
 Frame = -2

Query: 164 NCTYYWGFAAWMAYYINHPL-YTPPTYGVQQVKLALAVFVICQLGNFSIHMALRDLRPAG 222
           N  YYW   + +AY++NHP    PP YG  QV   LA F   +LGNFSIH+A R+LRPAG
Sbjct: 398 NSIYYWA-CSLVAYFVNHPPPXLPPAYGDMQVYGGLAAFAFAELGNFSIHIAFRNLRPAG 222

Query: 223 SKTRKIPYPTKNPFTWLFLLVSCPNYTYEVGSWIGFAILTQCVPVALFSLVGFTQMTIWA 282
           SK RKIPY T NP TW+F LVSCPNYTYE  +WI F+++TQC+P  LF+L GF QM +WA
Sbjct: 221 SKERKIPYSTSNPMTWMFGLVSCPNYTYEAMAWIAFSVMTQCLPAGLFTLAGFYQMAVWA 42

Query: 283 KGKHRSYLKEFRD 295
           KGKHR+Y+KEF++
Sbjct: 41  KGKHRNYVKEFKN 3
>32229
          Length = 644

 Score = 30.8 bits (68), Expect = 0.78,   Method: Compositional matrix adjust.
 Identities = 33/125 (26%), Positives = 50/125 (40%), Gaps = 9/125 (7%)
 Frame = +3

Query: 60  KDEDVLQK--LPVGTTATLYFRDLGAQISWVTVFLTEYAGPLFIYLLFYFRVPF------ 111
           +  DV  +  LP  T+  +      A IS+ +V +  +A    I       +P       
Sbjct: 24  ESSDVPHRH*LPSNTSVAVISYTSVAVISYTSVAVISHASVAVISHTSVAVIPLKAL*CV 203

Query: 112 IYGRKYDFTSSRHTVVHLACMCHSFHYIKRLLETLFVHRFSHGTMPLRNIFKNC-TYYWG 170
           I   KYD ++  H + H A  CHSF       E + +H     + P  + F +C  YY G
Sbjct: 204 IILFKYDISNGHHNIHHHAQYCHSF-------EGIVMH-----SCP*IHTFDSCYLYYHG 347

Query: 171 FAAWM 175
           F   M
Sbjct: 348 FEGIM 362
>03675
          Length = 1703

 Score = 29.3 bits (64), Expect = 1.9,   Method: Compositional matrix adjust.
 Identities = 20/65 (30%), Positives = 31/65 (47%), Gaps = 1/65 (1%)
 Frame = -3

Query: 215 LRDLRPAGSKTRKIPYPTKNPFTWLFLLVSCPNYTYEVGSWIG-FAILTQCVPVALFSLV 273
           L  L+P G  +R +    +N    L     CP YT+ V SW     ++  C  +++ S+V
Sbjct: 936 LNKLKPGGYGSRLLALFQQN*---L*FNQCCPVYTFCVHSWFSQIVLVILCCLLSILSVV 766

Query: 274 GFTQM 278
            FT M
Sbjct: 765 VFTNM 751
>06288
          Length = 1157

 Score = 28.1 bits (61), Expect = 4.9,   Method: Compositional matrix adjust.
 Identities = 12/33 (36%), Positives = 20/33 (60%)
 Frame = -3

Query: 264 CVPVALFSLVGFTQMTIWAKGKHRSYLKEFRDY 296
           CV + L        MTI+ KG +R ++K+F+D+
Sbjct: 555 CVQITL------NNMTIFRKGSYRFFIKKFKDF 475
>01498
          Length = 1879

 Score = 27.7 bits (60), Expect = 5.7,   Method: Compositional matrix adjust.
 Identities = 13/24 (54%), Positives = 17/24 (70%)
 Frame = -3

Query: 220  PAGSKTRKIPYPTKNPFTWLFLLV 243
            PAGS  R++P PTKNPF+    L+
Sbjct: 1565 PAGSH-RRLPVPTKNPFSRDLTLL 1497
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|21313554|ref|NP_079744.1| Sec11-like 3 [Mus musculus]
         (192 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

08585                                                                 175   1e-44
28671                                                                  28   1.7  
31539                                                                  28   2.7  
>08585
          Length = 2828

 Score =  175 bits (443), Expect = 1e-44,   Method: Compositional matrix adjust.
 Identities = 82/107 (76%), Positives = 94/107 (87%)
 Frame = +3

Query: 85   REDPIRAGEIVVFKVEGRDIPIVHRVIKVHEKDNGDIKFLTKGDNNEVDDRGLYKEGQNW 144
            R   I AGEIVVFKVEGRDIPIVHRV+K+HEK++G +KFLTKGDNN VDDRGLY  GQ W
Sbjct: 1953 RRVAITAGEIVVFKVEGRDIPIVHRVLKIHEKEDGSVKFLTKGDNNSVDDRGLYAPGQFW 2132

Query: 145  LEKKDVVGRARGFLPYVGMVTIIMNDYPKFKYALLAVMGAYVLLKRE 191
            LEKKDVVGRARGF+PYVG+VTI+MNDYPKFKYA+L  +G +VL+ RE
Sbjct: 2133 LEKKDVVGRARGFVPYVGIVTILMNDYPKFKYAILVCLGIFVLVHRE 2273
>28671
          Length = 1156

 Score = 28.5 bits (62), Expect = 1.7,   Method: Compositional matrix adjust.
 Identities = 12/32 (37%), Positives = 19/32 (59%)
 Frame = +2

Query: 138 YKEGQNWLEKKDVVGRARGFLPYVGMVTIIMN 169
           ++ G+  +EKK +  RARGF P  G+  +  N
Sbjct: 743 WRLGKGLVEKKKLRKRARGFCPAWGVTVLTAN 838
>31539
          Length = 346

 Score = 27.7 bits (60), Expect = 2.7,   Method: Compositional matrix adjust.
 Identities = 17/47 (36%), Positives = 24/47 (51%), Gaps = 10/47 (21%)
 Frame = +2

Query: 98  KVEGRDIPIVHRVIKVH----------EKDNGDIKFLTKGDNNEVDD 134
           K E  D+PIVH+VI  H          +KD  + K ++ GD + V D
Sbjct: 188 KSENDDVPIVHKVIDHHDDASKPDAAADKDQCEGKAVSGGDGSPVTD 328
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6681203|ref|NP_031894.1| dystrophin, muscular
dystrophy [Mus musculus]
         (3678 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

19002                                                                 180   1e-44
17613                                                                  53   2e-19
19147                                                                  90   2e-17
29446                                                                  80   2e-14
05733                                                                  63   2e-09
09711                                                                  62   3e-09
25483                                                                  61   7e-09
09100                                                                  54   1e-06
34417                                                                  50   1e-05
04951                                                                  45   4e-04
32088                                                                  38   0.061
26162                                                                  33   1.9  
14299                                                                  33   1.9  
38263                                                                  33   2.0  
18202                                                                  32   4.0  
12262                                                                  32   4.2  
>19002
          Length = 842

 Score =  180 bits (456), Expect = 1e-44,   Method: Compositional matrix adjust.
 Identities = 89/197 (45%), Positives = 129/197 (65%), Gaps = 1/197 (0%)
 Frame = -2

Query: 46  DGKRLLDLLE-GLTGQKLPKEKGSTRVHALNNVNKALRVLQKNNVDLVNIGSTDIVDGNH 104
           DGK L+ LLE  + G+     KG  R+H L NV+KAL  L +  V L N+G+ DIVDG+ 
Sbjct: 841 DGKMLMKLLEVRVRGEIASDXKGKMRIHCLENVDKALTFLHEQRVHLENMGAHDIVDGSS 662

Query: 105 KLTLGLIWNIILHWQVKNVMKTIMAGLQQTNSEKILLSWVRQSTRNYPQVNVINFTSSWS 164
           +LTLGLIW IIL +Q++++M   +   +  +++  LL W +  T  YP VNV NFT+SW 
Sbjct: 661 RLTLGLIWTIILRFQIQDIMIEEVDNSETKSAKDALLLWCQMKTAGYPNVNVRNFTTSWR 482

Query: 165 DGLALNALIHSHRPDLFDWNSVVSQHSATQRLEHAFNIAKCQLGIEKLLDPEDVATTYPD 224
           DGLA NA+IH HRPDL  ++  + + SA Q L++AF +A+ +LG+  LL+PEDV   YPD
Sbjct: 481 DGLAFNAIIHKHRPDLVQYDR-LHKSSAIQNLQNAFTVAEDKLGLTALLEPEDVNVEYPD 305

Query: 225 KKSILMYITSLFQVLPQ 241
           +KSI+ Y+ + +    +
Sbjct: 304 EKSIITYVVTYYHYFSK 254
>17613
          Length = 1108

 Score = 53.1 bits (126), Expect(3) = 2e-19,   Method: Composition-based stats.
 Identities = 30/73 (41%), Positives = 46/73 (63%)
 Frame = +1

Query: 132 QQTNSEKILLSWVRQSTRNYPQVNVINFTSSWSDGLALNALIHSHRPDLFDWNSVVSQHS 191
           ++T+ ++  +  V   T  Y  VNV NF  S+ DGLA  ALIH HRP+L D++S +S+ +
Sbjct: 175 RRTHCQRRTVIVVPAKTAPYKNVNVQNFHLSFKDGLAFCALIHRHRPELIDYHS-LSKDN 351

Query: 192 ATQRLEHAFNIAK 204
             + L  AF+IA+
Sbjct: 352 PLENLNTAFDIAE 390

 Score = 45.8 bits (107), Expect(3) = 2e-19,   Method: Compositional matrix adjust.
 Identities = 19/36 (52%), Positives = 29/36 (80%)
 Frame = +2

Query: 88  NVDLVNIGSTDIVDGNHKLTLGLIWNIILHWQVKNV 123
            V LV+IG+ +IVDGN K+TLG+IW IIL + ++++
Sbjct: 62  GVKLVSIGAEEIVDGNVKMTLGMIWTIILRFAIQDI 169

 Score = 37.7 bits (86), Expect(3) = 2e-19,   Method: Compositional matrix adjust.
 Identities = 15/44 (34%), Positives = 27/44 (61%), Gaps = 1/44 (2%)
 Frame = +3

Query: 197 EHAFNIAKCQLGIEKLLDPED-VATTYPDKKSILMYITSLFQVL 239
           +H F   +  L I ++LDPED V +  PD++S++ Y++S +   
Sbjct: 366 QHCF*HRRKHLDIPRMLDPEDMVNSAKPDERSVMAYVSSYYHAF 497
>19147
          Length = 474

 Score = 89.7 bits (221), Expect = 2e-17,   Method: Compositional matrix adjust.
 Identities = 44/103 (42%), Positives = 68/103 (66%)
 Frame = +1

Query: 84  LQKNNVDLVNIGSTDIVDGNHKLTLGLIWNIILHWQVKNVMKTIMAGLQQTNSEKILLSW 143
           +    V LV+IG+ +IVDGN K+TLG+IW IIL + ++++       +++  +++ LL W
Sbjct: 52  IASKGVKLVSIGAEEIVDGNVKMTLGMIWTIILRFAIQDIT------VEELTAKEGLLLW 213

Query: 144 VRQSTRNYPQVNVINFTSSWSDGLALNALIHSHRPDLFDWNSV 186
            ++ T  Y  VNV NF  S+ DGLA  ALIH HRP+L D++S+
Sbjct: 214 CQRKTAPYKNVNVQNFHLSFKDGLAFCALIHRHRPELIDYHSL 342
>29446
          Length = 1445

 Score = 79.7 bits (195), Expect = 2e-14,   Method: Compositional matrix adjust.
 Identities = 54/138 (39%), Positives = 76/138 (55%), Gaps = 9/138 (6%)
 Frame = +3

Query: 16   VQKKTFTKWINAQFSKFGKQHIDNLFSDLQDGKRLLDLLEGLTGQKLP--KEKGSTRVHA 73
            +QK TFT+W N       K  I +L SD  DG RL+ L+E L+G+K     ++ + R   
Sbjct: 999  IQKNTFTRWANEHLRTVNKA-IADLESDFSDGLRLVALIEVLSGKKFKHVNKRPNFRTQK 1175

Query: 74   LNNVNKALRVLQKN-NVDLVNIGSTDIVDGNHKLTLGLIWNIILHWQVKNVMKTIMAGLQ 132
            L NV   L+ L+ +  + +VNI STDIVD   KL LGLIW +ILH+ +   M     G +
Sbjct: 1176 LENVTLTLKFLEDDEGIRIVNIDSTDIVDKKLKLILGLIWTLILHYSISMPM---WEGEE 1346

Query: 133  QTNSE------KILLSWV 144
             T SE      + LL+W+
Sbjct: 1347 PTPSEGGPTPKQRLLNWI 1400
>05733
          Length = 1021

 Score = 63.2 bits (152), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 40/129 (31%), Positives = 70/129 (54%), Gaps = 3/129 (2%)
 Frame = +2

Query: 140 LLSWVRQ--STRNYPQVNVINFTSSWSDGLALNALIHSHRPDLFDWNSVVSQHSATQRLE 197
           LL W ++  +   Y  V++I+FTSSW  GLA  ALIH+ RP L    S++   +     +
Sbjct: 470 LLRWCQRVLNXGTYRGVHIIDFTSSWRSGLAFCALIHAFRPHLISPASLMECETVKNN-Q 646

Query: 198 HAFNIAKCQLGIEKLLDPEDV-ATTYPDKKSILMYITSLFQVLPQQVSIEAIQEVEMLPR 256
            AF++A+ +LGI  ++  ED+ A   PDK +++ Y++   ++       E +    +LP 
Sbjct: 647 LAFDVAQKELGIAPVMRGEDMAACAVPDKLTMVAYLSQFHELFKH----EPLPSSVLLPP 814

Query: 257 TSSKVTREE 265
            + +  +EE
Sbjct: 815 KTREQVKEE 841
>09711
          Length = 3041

 Score = 62.4 bits (150), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 61/236 (25%), Positives = 113/236 (47%), Gaps = 18/236 (7%)
 Frame = +1

Query: 6    EVEDCYEREDVQKKTFTKWINA-QFSKFGKQHIDNLFSDLQDGKRLLDLLE----GL--- 57
            EVED  + E  ++KT+  W+N+   S F    + +L+SDL DG  +  L +    GL   
Sbjct: 817  EVEDVMKEESREEKTYRNWMNSLGVSPF----VHHLYSDLYDGLIIFQLYDYIQPGLVDW 984

Query: 58   TGQKLPKEKGSTRVHALNNVNKALRV---LQKNNVDLVNIGSTDIVDGNHKLTLGLIWNI 114
            +  K    K   R   + N N A+ +   ++   V LV I   DI+DGN  LTLGL+W +
Sbjct: 985  SKVKKKFNKLKARFERIENCNYAVELGPQVKLVKVKLVGIAGQDILDGNPVLTLGLVWQL 1164

Query: 115  ILHWQVKNVMKTIMAGLQQTN---SEKILLSWVRQSTRNYPQVNVINFTSSWSDGLALNA 171
            +  + +      I++ + + N   S+  +++WV    +   +++        +DG+ +  
Sbjct: 1165 MRAYTL-----AILSKITENNKPISDNEIITWVNSKIKKDDRISGFQ-DRKLNDGVIVAR 1326

Query: 172  LIHSHRPDLFDWNSV-VSQHSATQRL---EHAFNIAKCQLGIEKLLDPEDVATTYP 223
            +I + +P + +W+++  S      RL    +A  +A+ ++G      PED+    P
Sbjct: 1327 VIEAIKPGIVNWDNIDCSARDYQDRLTNARYAIGLAR-KIGAGVYALPEDIVEVKP 1491

 Score = 35.4 bits (80), Expect = 0.37,   Method: Compositional matrix adjust.
 Identities = 62/267 (23%), Positives = 102/267 (38%), Gaps = 31/267 (11%)
 Frame = +1

Query: 17  QKKTFTKWINAQFSKFGK-QHI-------DNLFSDLQDGKRLLDLLEGLTGQKLPKEKGS 68
           ++K F +WIN   S     +H+         LF  + DG  L  L+       + +   +
Sbjct: 52  EQKAFAEWINRHLSDXPDCKHLLPLDADGTQLFGQMADGVLLCKLINHSVSNTIDERTIN 231

Query: 69  TRVHAL----NNVNKALRVLQKNNVDLVNIGSTDIVDGNHKLTLGLIWNIILHWQVKNV- 123
            +  +L     N+  A+          VNIG  D+  G   L LGL+W II    + ++ 
Sbjct: 232 KQNLSLYRRHENLTLAVNSAGAIGCTTVNIGPEDLAAGRPHLVLGLLWQIIRIGLLSDIN 411

Query: 124 -------MKTIMAG-----LQQTNSEKILLSWVRQS-TRNYPQVNVINFTSSWSDGLALN 170
                  +  ++ G     L + + E+ILL WV     R      + NF     D  A  
Sbjct: 412 LAHHPGLVNLLLDGETIEDLIRLSPEQILLRWVNYHLNRAGCDRQIXNFGEDIKDSEAYT 591

Query: 171 ALIHSHRPDLFDWN-SVVSQHSATQRLEHAFNIAKCQLGIEKLLDPEDVATTYPDKKSIL 229
            L+    P       S +S     QR E     A  ++G    +   DV +   ++K  L
Sbjct: 592 HLLKQISPPSAGVTLSPLSVGDVHQRAECMLQEAD-KIGCRSFVGASDVVSG--NQKLNL 762

Query: 230 MYITSLFQVLPQ----QVSIEAIQEVE 252
            ++ +LF   P     QV +E + + E
Sbjct: 763 AFVANLFNNYPALDTPQVEVEDVMKEE 843
>25483
          Length = 438

 Score = 61.2 bits (147), Expect = 7e-09,   Method: Compositional matrix adjust.
 Identities = 28/86 (32%), Positives = 52/86 (60%), Gaps = 3/86 (3%)
 Frame = -2

Query: 2158 QAVVRTLNATGEEIIQQSSKTDVNILQEKLGSLSLRWHDICKELAERRK---RIEEQKNV 2214
            Q  V ++N+ G E+++Q S    ++L+++  S++ RW  +C E+ ER+K   R+EE    
Sbjct: 425  QGTVNSMNSAGNEMLRQMSAPQADLLRQRQDSINQRWKALCSEVFERQKYAGRVEEGSTR 246

Query: 2215 LSEFQRDLNEFVLWLEEADNIAITPL 2240
             S+F  D++E   W++E +NI  + L
Sbjct: 245  TSDFTDDMDELFFWIDETENILASTL 168
>09100
          Length = 930

 Score = 53.9 bits (128), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 32/110 (29%), Positives = 58/110 (52%), Gaps = 3/110 (2%)
 Frame = +1

Query: 17  QKKTFTKWINAQFSKFGKQH-IDNLFSDLQDGKRLLDLLEGLTGQKLP--KEKGSTRVHA 73
           Q   +  WIN+Q  K    H I++L  D++DG    D++  ++ Q++P  +   +T    
Sbjct: 463 QLSAYMAWINSQLKKKPGAHLIEDLRHDMRDGVVFADVIHIVSKQQIPGIQNVPTTLDEM 642

Query: 74  LNNVNKALRVLQKNNVDLVNIGSTDIVDGNHKLTLGLIWNIILHWQVKNV 123
             NV++ L  + +N + +  I S DIV+GN K  + LI  +  H++  +V
Sbjct: 643 RQNVDRVLHFMTQNRIKMHRISSRDIVEGNLKAVMRLILALAAHYKPMSV 792
>34417
          Length = 1096

 Score = 50.4 bits (119), Expect = 1e-05,   Method: Composition-based stats.
 Identities = 30/82 (36%), Positives = 44/82 (53%), Gaps = 1/82 (1%)
 Frame = +2

Query: 159 FTSSWSDGLALNALIHSHRPDLFDWNSVVSQHSATQRLEHAFNIAKCQLGIEKLLDPED- 217
            +S W++GLA  ALIH   PD FD++ +  Q+      E AF+ A+    I  LLD ED 
Sbjct: 35  LSSCWNNGLAFCALIHHFYPDAFDYSQLQPQNR-RYNFELAFDTAEKLADISPLLDVEDM 211

Query: 218 VATTYPDKKSILMYITSLFQVL 239
           +    PD K +  Y+ S ++ L
Sbjct: 212 IKMKNPDWKCVFTYVQSFYRHL 277
>04951
          Length = 2852

 Score = 45.4 bits (106), Expect = 4e-04,   Method: Composition-based stats.
 Identities = 37/137 (27%), Positives = 64/137 (46%), Gaps = 4/137 (2%)
 Frame = +1

Query: 91  LVNIGSTDIVDGNHKLTLGLIWNIILHWQVKNVMKTIMAGLQQTNSEKILLSWVRQSTRN 150
           LV IG  DI DGN  LTLGL+W ++  + +  + K         +SE  ++ WV    + 
Sbjct: 67  LVGIGGKDIHDGNPVLTLGLVWQLMRAYTLAILSKLTEDKKPIQDSE--IVDWVNSKVKK 240

Query: 151 YPQVNVINFTSSWSDGLALNALIHSHRPDLFDWNSVVSQHS-ATQRL---EHAFNIAKCQ 206
             ++      S  +DG+ +  +I S +P + +W ++    S    RL    +A  +A+ +
Sbjct: 241 DERIGSFQ-DSKLNDGVIVAKVIESIKPGIVNWENINPNASEPDDRLANARYAIGLAR-K 414

Query: 207 LGIEKLLDPEDVATTYP 223
           +G      PED+    P
Sbjct: 415 IGAGVYALPEDIVEVKP 465
>32088
          Length = 1928

 Score = 38.1 bits (87), Expect = 0.061,   Method: Composition-based stats.
 Identities = 40/156 (25%), Positives = 63/156 (40%), Gaps = 25/156 (16%)
 Frame = +1

Query: 14   EDVQKKTFTKWINAQFSKFGK-QHI-------DNLFSDLQDGKRLLDLLEGLTGQKLPKE 65
            +D ++K F  WIN         +H+       D+LF  + DG  L  L+       + + 
Sbjct: 1255 KDGEQKAFAAWINRHLKDDPDCKHLMEVNEEGDDLFKKVGDGILLCKLINHSVSNTIDER 1434

Query: 66   ---KGSTRV-HALNNVNKALRVLQKNNVDLVNIGSTDIVDGNHKLTLGLIWNIIL----- 116
               K +  V H   N+  A+          VNIG  D+  G   L LGL+W II      
Sbjct: 1435 AINKSNLNVYHRHENLTLAVNSAGSIGCTTVNIGPEDLAAGRPHLVLGLLWQIIRIGLLS 1614

Query: 117  ------HWQVKNVMK--TIMAGLQQTNSEKILLSWV 144
                  H  + N+++    +    + + E+ILL WV
Sbjct: 1615 DINLAHHPGLVNLLREGETIEDFMRLSPEEILLRWV 1722
>26162
          Length = 608

 Score = 33.1 bits (74), Expect = 1.9,   Method: Composition-based stats.
 Identities = 19/55 (34%), Positives = 27/55 (49%)
 Frame = +1

Query: 3054 WERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRL 3108
            WER I  +   YY++H T+TT W  P  TE+  +  +    R +    AM  R L
Sbjct: 190  WERRIDQHGRVYYVDHNTRTTTWQRPN-TEMVTNWNNWQQWRNNRTMDAMNQRFL 351
>14299
          Length = 716

 Score = 33.1 bits (74), Expect = 1.9,   Method: Composition-based stats.
 Identities = 17/64 (26%), Positives = 32/64 (50%), Gaps = 1/64 (1%)
 Frame = +3

Query: 3300 AKHQA-KCNICKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYCTPTTS 3358
            ++H+   C+ C +    G RY+ L  ++YD+C +C+ +G     H   + +   C  T S
Sbjct: 249  SRHEGVSCDSCLKGNFRGRRYKCLICYDYDLCATCYEAGATTTRHTTDHAV--QCILTRS 422

Query: 3359 GEDV 3362
              D+
Sbjct: 423  DFDM 434
>38263
          Length = 368

 Score = 33.1 bits (74), Expect = 2.0,   Method: Composition-based stats.
 Identities = 13/45 (28%), Positives = 25/45 (55%), Gaps = 1/45 (2%)
 Frame = +2

Query: 3300 AKHQA-KCNICKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGH 3343
            ++H+   C+ C +    G RY+ L  ++YD+C +C+ +G     H
Sbjct: 188  SRHEGVSCDSCLKGNFRGRRYKCLICYDYDLCATCYEAGATTTRH 322
>18202
          Length = 424

 Score = 32.3 bits (72), Expect = 4.0,   Method: Composition-based stats.
 Identities = 30/134 (22%), Positives = 67/134 (50%), Gaps = 7/134 (5%)
 Frame = -1

Query: 19  KTFTKWINAQFSKFGKQHIDNLFSDLQDGKRLLDLLEGLTGQK--LPKEKGSTRVHALNN 76
           + +  W N+   +     ++N+ S +Q+G+ L +L++ L  +   L K + S +      
Sbjct: 385 QVYLSWANSVLCEVNSS-VENV-SSIQEGRVLCELIDVLAPEAGLLDKVQASGKSGQRAF 212

Query: 77  VNKALRVLQKNNVDLVNIGSTDIVDGNHKLTLGLIWNIILHWQV-----KNVMKTIMAGL 131
           +  AL  ++ + + +V   + DI+DG+ K  L ++W +IL++ +      +  +++ AG 
Sbjct: 211 IYAALDHMKNHGIKIV-FSTQDIMDGDIKSLLDVMWLLILNYGIHFIGNNSFQRSVGAG- 38

Query: 132 QQTNSEKILLSWVR 145
                +K LL W +
Sbjct: 37  -----KKNLLDWCQ 11
>12262
          Length = 739

 Score = 32.0 bits (71), Expect = 4.2,   Method: Composition-based stats.
 Identities = 15/31 (48%), Positives = 20/31 (64%)
 Frame = -1

Query: 1949 PTQIQLSKRWRQIESNFAQFRRLNFAQIHTL 1979
            PT  QL    R IES ++Q RR+N  +IHT+
Sbjct: 703  PTHTQLLNTMR*IESQYSQCRRINVGEIHTV 611
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|110431378|ref|NP_035812.3| utrophin [Mus musculus]
         (3430 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

19002                                                                 179   2e-44
19147                                                                  95   6e-19
17613                                                                  60   1e-10
05733                                                                  63   2e-09
09711                                                                  51   1e-05
29446                                                                  50   2e-05
04951                                                                  49   4e-05
32088                                                                  39   0.054
09100                                                                  37   0.093
14299                                                                  37   0.15 
38263                                                                  36   0.27 
24182                                                                  35   0.60 
25483                                                                  33   2.5  
26162                                                                  32   3.9  
18556                                                                  32   4.5  
12851                                                                  31   7.5  
>19002
          Length = 842

 Score =  179 bits (453), Expect = 2e-44,   Method: Compositional matrix adjust.
 Identities = 81/175 (46%), Positives = 120/175 (68%)
 Frame = -2

Query: 82  RGSTRVHALNNVNRVLQVLHQNNVDLVNIGGTDIVDGNPKLTLGLLWSIILHWQVKDVMK 141
           +G  R+H L NV++ L  LH+  V L N+G  DIVDG+ +LTLGL+W+IIL +Q++D+M 
Sbjct: 778 KGKMRIHCLENVDKALTFLHEQRVHLENMGAHDIVDGSSRLTLGLIWTIILRFQIQDIMI 599

Query: 142 DIMSDLQQTNSEKILLSWVRQTTRPYSQVNVLNFTTSWTDGLAFNAVLHRHKPDLFSWDR 201
           + + + +  +++  LL W +  T  Y  VNV NFTTSW DGLAFNA++H+H+PDL  +DR
Sbjct: 598 EEVDNSETKSAKDALLLWCQMKTAGYPNVNVRNFTTSWRDGLAFNAIIHKHRPDLVQYDR 419

Query: 202 VVKMSPIERLEHAFSKAHTYLGIEKLLDPEDVAVHLPDKKSIIMYLTSLFEVLPQ 256
           + K S I+ L++AF+ A   LG+  LL+PEDV V  PD+KSII Y+ + +    +
Sbjct: 418 LHKSSAIQNLQNAFTVAEDKLGLTALLEPEDVNVEYPDEKSIITYVVTYYHYFSK 254
>19147
          Length = 474

 Score = 94.7 bits (234), Expect = 6e-19,   Method: Compositional matrix adjust.
 Identities = 45/113 (39%), Positives = 73/113 (64%)
 Frame = +1

Query: 104 NVDLVNIGGTDIVDGNPKLTLGLLWSIILHWQVKDVMKDIMSDLQQTNSEKILLSWVRQT 163
            V LV+IG  +IVDGN K+TLG++W+IIL + ++D+       +++  +++ LL W ++ 
Sbjct: 64  GVKLVSIGAEEIVDGNVKMTLGMIWTIILRFAIQDI------TVEELTAKEGLLLWCQRK 225

Query: 164 TRPYSQVNVLNFTTSWTDGLAFNAVLHRHKPDLFSWDRVVKMSPIERLEHAFS 216
           T PY  VNV NF  S+ DGLAF A++HRH+P+L  +  + K+S +  +    S
Sbjct: 226 TAPYKNVNVQNFHLSFKDGLAFCALIHRHRPELIDYHSLSKVSLLNTVVQTLS 384
>17613
          Length = 1108

 Score = 50.1 bits (118), Expect(2) = 1e-10,   Method: Composition-based stats.
 Identities = 23/62 (37%), Positives = 41/62 (66%)
 Frame = +2

Query: 105 VDLVNIGGTDIVDGNPKLTLGLLWSIILHWQVKDVMKDIMSDLQQTNSEKILLSWVRQTT 164
           V LV+IG  +IVDGN K+TLG++W+IIL + ++D+       +++  +++ LL W ++  
Sbjct: 65  VKLVSIGAEEIVDGNVKMTLGMIWTIILRFAIQDIT------VEELTAKEGLLLWCQRKQ 226

Query: 165 RP 166
            P
Sbjct: 227 HP 232

 Score = 37.0 bits (84), Expect(2) = 1e-10,   Method: Compositional matrix adjust.
 Identities = 18/54 (33%), Positives = 29/54 (53%), Gaps = 1/54 (1%)
 Frame = +3

Query: 202 VVKMSPIERLEHAFSKAHTYLGIEKLLDPED-VAVHLPDKKSIIMYLTSLFEVL 254
            VK   I   +H F     +L I ++LDPED V    PD++S++ Y++S +   
Sbjct: 336 TVKGQSIGEPQHCF*HRRKHLDIPRMLDPEDMVNSAKPDERSVMAYVSSYYHAF 497

 Score = 59.7 bits (143), Expect = 2e-08,   Method: Composition-based stats.
 Identities = 29/71 (40%), Positives = 44/71 (61%)
 Frame = +1

Query: 148 QQTNSEKILLSWVRQTTRPYSQVNVLNFTTSWTDGLAFNAVLHRHKPDLFSWDRVVKMSP 207
           ++T+ ++  +  V   T PY  VNV NF  S+ DGLAF A++HRH+P+L  +  + K +P
Sbjct: 175 RRTHCQRRTVIVVPAKTAPYKNVNVQNFHLSFKDGLAFCALIHRHRPELIDYHSLSKDNP 354

Query: 208 IERLEHAFSKA 218
           +E L  AF  A
Sbjct: 355 LENLNTAFDIA 387
>05733
          Length = 1021

 Score = 63.2 bits (152), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 38/129 (29%), Positives = 71/129 (55%), Gaps = 3/129 (2%)
 Frame = +2

Query: 156 LLSWVRQTTR--PYSQVNVLNFTTSWTDGLAFNAVLHRHKPDLFSWDRVVKMSPIERLEH 213
           LL W ++      Y  V++++FT+SW  GLAF A++H  +P L S   +++   ++  + 
Sbjct: 470 LLRWCQRVLNXGTYRGVHIIDFTSSWRSGLAFCALIHAFRPHLISPASLMECETVKNNQL 649

Query: 214 AFSKAHTYLGIEKLLDPEDV-AVHLPDKKSIIMYLTSLFEVLPQQVTIDAIREVETLPRK 272
           AF  A   LGI  ++  ED+ A  +PDK +++ YL+   E+   +    ++     LP K
Sbjct: 650 AFDVAQKELGIAPVMRGEDMAACAVPDKLTMVAYLSQFHELFKHEPLPSSV----LLPPK 817

Query: 273 YKKECEEEE 281
            +++ +EE+
Sbjct: 818 TREQVKEEK 844
>09711
          Length = 3041

 Score = 50.8 bits (120), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 30/101 (29%), Positives = 52/101 (51%), Gaps = 3/101 (2%)
 Frame = +1

Query: 105  VDLVNIGGTDIVDGNPKLTLGLLWSIILHWQVKDVMKDIMSDLQQTN---SEKILLSWVR 161
            V LV I G DI+DGNP LTLGL+W ++  + +      I+S + + N   S+  +++WV 
Sbjct: 1087 VKLVGIAGQDILDGNPVLTLGLVWQLMRAYTLA-----ILSKITENNKPISDNEIITWVN 1251

Query: 162  QTTRPYSQVNVLNFTTSWTDGLAFNAVLHRHKPDLFSWDRV 202
               +   +++         DG+    V+   KP + +WD +
Sbjct: 1252 SKIKKDDRISGFQ-DRKLNDGVIVARVIEAIKPGIVNWDNI 1371

 Score = 41.6 bits (96), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 44/168 (26%), Positives = 68/168 (40%), Gaps = 20/168 (11%)
 Frame = +1

Query: 108 VNIGGTDIVDGNPKLTLGLLWSIILHWQVKDVM-------------KDIMSDLQQTNSEK 154
           VNIG  D+  G P L LGLLW II    + D+               + + DL + + E+
Sbjct: 313 VNIGPEDLAAGRPHLVLGLLWQIIRIGLLSDINLAHHPGLVNLLLDGETIEDLIRLSPEQ 492

Query: 155 ILLSWVR-QTTRPYSQVNVLNFTTSWTDGLAFNAVLHRHKPDLFSWDRVVKMSPI----- 208
           ILL WV     R      + NF     D  A+  +L +  P        V +SP+     
Sbjct: 493 ILLRWVNYHLNRAGCDRQIXNFGEDIKDSEAYTHLLKQISPP----SAGVTLSPLSVGDV 660

Query: 209 -ERLEHAFSKAHTYLGIEKLLDPEDVAVHLPDKKSIIMYLTSLFEVLP 255
            +R E    +A   +G    +   DV     ++K  + ++ +LF   P
Sbjct: 661 HQRAECMLQEADK-IGCRSFVGASDVVSG--NQKLNLAFVANLFNNYP 795
>29446
          Length = 1445

 Score = 50.1 bits (118), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 36/109 (33%), Positives = 50/109 (45%), Gaps = 4/109 (3%)
 Frame = +3

Query: 32   VQKKTFTKWINARFSKSGKPPISDM---FXXXXXXXXXXXXXXXXXXXXXPKERGSTRVH 88
            +QK TFT+W N       K  I+D+   F                      K R + R  
Sbjct: 999  IQKNTFTRWANEHLRTVNKA-IADLESDFSDGLRLVALIEVLSGKKFKHVNK-RPNFRTQ 1172

Query: 89   ALNNVNRVLQVLHQN-NVDLVNIGGTDIVDGNPKLTLGLLWSIILHWQV 136
             L NV   L+ L  +  + +VNI  TDIVD   KL LGL+W++ILH+ +
Sbjct: 1173 KLENVTLTLKFLEDDEGIRIVNIDSTDIVDKKLKLILGLIWTLILHYSI 1319
>04951
          Length = 2852

 Score = 48.9 bits (115), Expect = 4e-05,   Method: Composition-based stats.
 Identities = 31/110 (28%), Positives = 55/110 (50%), Gaps = 2/110 (1%)
 Frame = +1

Query: 107 LVNIGGTDIVDGNPKLTLGLLWSIILHWQVKDVMKDIMSDLQQTNSEKILLSWVRQTTRP 166
           LV IGG DI DGNP LTLGL+W ++  + +  ++  +  D +     +I + WV    + 
Sbjct: 67  LVGIGGKDIHDGNPVLTLGLVWQLMRAYTLA-ILSKLTEDKKPIQDSEI-VDWVNSKVKK 240

Query: 167 YSQVNVLNFTTSWTDGLAFNAVLHRHKPDLFSWDRVVKMS--PIERLEHA 214
             ++      +   DG+    V+   KP + +W+ +   +  P +RL +A
Sbjct: 241 DERIGSFQ-DSKLNDGVIVAKVIESIKPGIVNWENINPNASEPDDRLANA 387
>32088
          Length = 1928

 Score = 38.5 bits (88), Expect = 0.054,   Method: Compositional matrix adjust.
 Identities = 26/82 (31%), Positives = 36/82 (43%), Gaps = 14/82 (17%)
 Frame = +1

Query: 108  VNIGGTDIVDGNPKLTLGLLWSIILHWQVKDVM-------------KDIMSDLQQTNSEK 154
            VNIG  D+  G P L LGLLW II    + D+               + + D  + + E+
Sbjct: 1525 VNIGPEDLAAGRPHLVLGLLWQIIRIGLLSDINLAHHPGLVNLLREGETIEDFMRLSPEE 1704

Query: 155  ILLSWVR-QTTRPYSQVNVLNF 175
            ILL WV     R  +   + NF
Sbjct: 1705 ILLRWVNYHLERAGTDRRIANF 1770
>09100
          Length = 930

 Score = 37.4 bits (85), Expect = 0.093,   Method: Compositional matrix adjust.
 Identities = 16/44 (36%), Positives = 27/44 (61%)
 Frame = +1

Query: 92  NVNRVLQVLHQNNVDLVNIGGTDIVDGNPKLTLGLLWSIILHWQ 135
           NV+RVL  + QN + +  I   DIV+GN K  + L+ ++  H++
Sbjct: 649 NVDRVLHFMTQNRIKMHRISSRDIVEGNLKAVMRLILALAAHYK 780
>14299
          Length = 716

 Score = 37.0 bits (84), Expect = 0.15,   Method: Composition-based stats.
 Identities = 19/64 (29%), Positives = 34/64 (53%), Gaps = 1/64 (1%)
 Frame = +3

Query: 3062 AKHQA-KCNICKECPIVGFRYRSLKHFNYDVCQSCFFSGRTAKGHKLHYPMVEYCIPTTS 3120
            ++H+   C+ C +    G RY+ L  ++YD+C +C+ +G T   H   + +   CI T S
Sbjct: 249  SRHEGVSCDSCLKGNFRGRRYKCLICYDYDLCATCYEAGATTTRHTTDHAV--QCILTRS 422

Query: 3121 GEDV 3124
              D+
Sbjct: 423  DFDM 434
>38263
          Length = 368

 Score = 35.8 bits (81), Expect = 0.27,   Method: Composition-based stats.
 Identities = 18/60 (30%), Positives = 32/60 (53%), Gaps = 1/60 (1%)
 Frame = +2

Query: 3062 AKHQA-KCNICKECPIVGFRYRSLKHFNYDVCQSCFFSGRTAKGHKLHYPMVEYCIPTTS 3120
            ++H+   C+ C +    G RY+ L  ++YD+C +C+ +G T   H   + +   CI T S
Sbjct: 188  SRHEGVSCDSCLKGNFRGRRYKCLICYDYDLCATCYEAGATTTRHTTDHAV--QCILTRS 361
>24182
          Length = 1269

 Score = 34.7 bits (78), Expect = 0.60,   Method: Compositional matrix adjust.
 Identities = 33/84 (39%), Positives = 47/84 (55%), Gaps = 3/84 (3%)
 Frame = +2

Query: 2412 EETTEYLKTSWVNLKQSIADRQSALEAELQTVQTSRRDLENFVKWLQ-EAETTANVLAD- 2469
            EE  + L  S  +L+QS ADR++ LE  + + +T   DLE+ V  LQ E      VL+D 
Sbjct: 212  EENEKSLMDSLTSLQQSAADRETELEEVIDSHKTHXTDLEDKVLSLQNEVSLKDTVLSDM 391

Query: 2470 ASQRENALQD-SVLARQLRQQMLD 2492
             SQ +  L+D    A Q+RQQ+ D
Sbjct: 392  ESQCKQQLEDLQSSAAQVRQQLED 463
>25483
          Length = 438

 Score = 32.7 bits (73), Expect = 2.5,   Method: Compositional matrix adjust.
 Identities = 33/119 (27%), Positives = 57/119 (47%), Gaps = 8/119 (6%)
 Frame = -2

Query: 1933 DVIVEASGPEAIQIRDMLAQLNAKWDRV-NRVYSDRRGSFARAVEEWR----QFHHDLDD 1987
            +++ + S P+A  +R     +N +W  + + V+   R  +A  VEE       F  D+D+
Sbjct: 389  EMLRQMSAPQADLLRQRQDSINQRWKALCSEVFE--RQKYAGRVEEGSTRTSDFTDDMDE 216

Query: 1988 LTQWLSEAEDLLVDTCAPDG---SLDLEKARAQQLELEEGLSSHQPSLIKVNRKGEDLV 2043
            L  W+ E E++L  T   +    S  LEK + +Q    E ++S Q +L  +   G  LV
Sbjct: 215  LFFWIDETENILASTLKLETQYLSDLLEKVKDRQ----EDVASRQQNLTAIQTNGTRLV 51
>26162
          Length = 608

 Score = 32.0 bits (71), Expect = 3.9,   Method: Composition-based stats.
 Identities = 11/26 (42%), Positives = 16/26 (61%)
 Frame = +1

Query: 2816 WQRSISHNKVPYYINHQTQTTCWDHP 2841
            W+R I  +   YY++H T+TT W  P
Sbjct: 190  WERRIDQHGRVYYVDHNTRTTTWQRP 267
>18556
          Length = 799

 Score = 32.0 bits (71), Expect = 4.5,   Method: Compositional matrix adjust.
 Identities = 15/50 (30%), Positives = 27/50 (54%)
 Frame = +2

Query: 179 WTDGLAFNAVLHRHKPDLFSWDRVVKMSPIERLEHAFSKAHTYLGIEKLL 228
           + +G    A++ R +PDL  +     MSP+E  E AF+     L I++++
Sbjct: 119 FRNGRVLCALISRFRPDLIDYAATKDMSPLECNELAFAVLERELHIDRIM 268
>12851
          Length = 1291

 Score = 31.2 bits (69), Expect = 7.5,   Method: Compositional matrix adjust.
 Identities = 13/30 (43%), Positives = 17/30 (56%)
 Frame = +1

Query: 2813 QLPWQRSISHNKVPYYINHQTQTTCWDHPK 2842
            Q PW+   S +   YY N QT+ +CW  PK
Sbjct: 445  QCPWKEYKSDSGKVYYHNSQTKESCWTKPK 534
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6680019|ref|NP_032155.1| glutamate-cysteine ligase,
modifier subunit [Mus musculus]
         (274 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

13564                                                                 175   2e-44
31792                                                                  35   0.039
17411                                                                  35   0.047
24743                                                                  31   0.67 
02477                                                                  30   1.1  
>13564
          Length = 842

 Score =  175 bits (444), Expect = 2e-44,   Method: Compositional matrix adjust.
 Identities = 85/163 (52%), Positives = 118/163 (72%)
 Frame = +1

Query: 109 AVDMACSVLGVAQLDSVIMASPPIEDGVNLSLEHLQPYWEELENLVQSKKIVAIGTSDLD 168
           AV+     L V+ +++V+++    +    +++E L+PYW+ LE+LV  +++++IG +DLD
Sbjct: 13  AVEKVMGELQVSFVETVLLSLSMYDSEDQIAVEELKPYWKALEDLVDQERVLSIGVADLD 192

Query: 169 KTQLEQLYQWAQVKPNSNQVNLASCCVMPPDLTAFAKQFDIQLLTHNDPKELLSEASFQE 228
           K +L+QLYQWA+VKP  NQVNLASCCVMP DLT +AKQ DIQL THNDP E L  +  Q+
Sbjct: 193 KHKLDQLYQWAKVKPRINQVNLASCCVMPKDLTEYAKQVDIQLQTHNDPPEYLPSSQLQD 372

Query: 229 ALQESIPDIEAQDWVPLWLLRYSVIVKSRGIIKSKGYILQAKR 271
           AL+    D ++  W  LW+ RYSV+VK RGIIKSKGYIL A+R
Sbjct: 373 ALRPCGTDQDSFGWSALWVARYSVLVKCRGIIKSKGYILHAER 501
>31792
          Length = 377

 Score = 34.7 bits (78), Expect = 0.039,   Method: Compositional matrix adjust.
 Identities = 23/64 (35%), Positives = 36/64 (56%)
 Frame = -3

Query: 148 EELENLVQSKKIVAIGTSDLDKTQLEQLYQWAQVKPNSNQVNLASCCVMPPDLTAFAKQF 207
           +ELE LVQ  KI ++G S+ +  Q++ +   A VKP  NQV      +   +L AF ++ 
Sbjct: 372 KELEKLVQEGKIRSLGISNFNSVQVDLINFVATVKPVINQVE-CHAYLAQKELQAFCQKR 196

Query: 208 DIQL 211
           +I L
Sbjct: 195 NIFL 184
>17411
          Length = 1104

 Score = 34.7 bits (78), Expect = 0.047,   Method: Compositional matrix adjust.
 Identities = 20/68 (29%), Positives = 36/68 (52%)
 Frame = -3

Query: 147 WEELENLVQSKKIVAIGTSDLDKTQLEQLYQWAQVKPNSNQVNLASCCVMPPDLTAFAKQ 206
           ++ +E LV+   + +IG S+ +  QL ++    ++KP +NQV   S  +    L AF KQ
Sbjct: 643 YKAMEQLVKIGLVRSIGVSNFNSEQLLRVINNCEIKPVTNQVE-CSPAINQKKLIAFCKQ 467

Query: 207 FDIQLLTH 214
             + L  +
Sbjct: 466 HGVTLTAY 443
>24743
          Length = 342

 Score = 30.8 bits (68), Expect = 0.67,   Method: Compositional matrix adjust.
 Identities = 27/109 (24%), Positives = 45/109 (41%), Gaps = 11/109 (10%)
 Frame = +3

Query: 104 SSTRSAVDMACSVLGVAQLDSVIMASPPIEDGVNLSLEHLQPY-----------WEELEN 152
            S R+A   + S L  + LD  ++  P  +         LQP+           W ++E 
Sbjct: 30  GSCRAACLQSLSRLQCSYLDLFLIHWPGTQK--------LQPHDARHKANRLXSWADMEQ 185

Query: 153 LVQSKKIVAIGTSDLDKTQLEQLYQWAQVKPNSNQVNLASCCVMPPDLT 201
           L +  K+ AIG S+  +  LE++     V+P      L   C + P +T
Sbjct: 186 LHKEGKLKAIGVSNFLQHHLEEILAVCSVRPAVYSC*LIRRCSL*PVVT 332
>02477
          Length = 1091

 Score = 30.0 bits (66), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 25/98 (25%), Positives = 41/98 (41%), Gaps = 11/98 (11%)
 Frame = +1

Query: 104 SSTRSAVDMACSVLGVAQLDSVIMASPPIEDGVNLSLEHLQPY-----------WEELEN 152
            S R+A   + S L  + LD  ++  P  +         LQP+           W ++E 
Sbjct: 7   GSCRAACLQSLSRLQCSYLDLFLIHWPGTQK--------LQPHDARHKANRLASWADMEQ 162

Query: 153 LVQSKKIVAIGTSDLDKTQLEQLYQWAQVKPNSNQVNL 190
           L +  K+ AIG S+  +  LE++     VKP   Q+  
Sbjct: 163 LHKEGKLKAIGVSNFLQHHLEEILAVCSVKPAVLQIEF 276
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6755899|ref|NP_035780.1| translin [Mus musculus]
         (228 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

06652                                                                 175   2e-44
17099                                                                  39   0.001
21396                                                                  30   1.1  
03071                                                                  29   1.9  
>06652
          Length = 902

 Score =  175 bits (443), Expect = 2e-44,   Method: Compositional matrix adjust.
 Identities = 76/160 (47%), Positives = 111/160 (69%)
 Frame = +3

Query: 38  ILTLLQGVHQGTGFQDIPKRCLKAREHFSTVKTHLTSLKTKFPAEQYYRFHEHWRFVLQR 97
           I ++LQ +HQ    + +   C KA   +  VK     L +K PA QYYRF++ WR+ +QR
Sbjct: 3   IQSVLQAIHQKAAQEHLLSACEKATPLYGKVKEQFAQLASKIPANQYYRFNDMWRYAIQR 182

Query: 98  LVFLAAFVVYLETETLVTREAVTEILGIEPDREKGFHLDVEDYLSGVLILASELSRLSVN 157
           + +LAA +VYL  + L+T++   ++LG++  RE GFH+D++D+L  +L LASELSR +VN
Sbjct: 183 IAYLAAMIVYLTKDRLITQQETADMLGVKVKREDGFHIDLDDFLMALLTLASELSRFAVN 362

Query: 158 SVTAGDYSRPLHISTFINELDSGFRLLNLKNDSLRKRYDG 197
           +V +GD  RP+ +S F+ ELD+GFRLLNLKND LRKR+D 
Sbjct: 363 AVVSGDPGRPIRVSKFLAELDAGFRLLNLKNDMLRKRFDS 482
>17099
          Length = 483

 Score = 39.3 bits (90), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 17/20 (85%), Positives = 19/20 (95%)
 Frame = -1

Query: 177 LDSGFRLLNLKNDSLRKRYD 196
           LD+GFRLLNLKND LRKR+D
Sbjct: 483 LDAGFRLLNLKNDMLRKRFD 424
>21396
          Length = 647

 Score = 29.6 bits (65), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 15/50 (30%), Positives = 26/50 (52%)
 Frame = -1

Query: 35  AREILTLLQGVHQGTGFQDIPKRCLKAREHFSTVKTHLTSLKTKFPAEQY 84
           +REI++ L  V++  G   +P+RCL  +   S    H    +T  P E++
Sbjct: 332 SREIVSALSPVYKRLGDPQLPQRCLSGKTQNSNESLHSMVWRT-CPKERW 186
>03071
          Length = 599

 Score = 28.9 bits (63), Expect = 1.9,   Method: Compositional matrix adjust.
 Identities = 22/66 (33%), Positives = 30/66 (45%), Gaps = 2/66 (3%)
 Frame = +1

Query: 28  VQSLEQTAREILTLLQGVHQGTGFQDIPKRCLKAREHFSTVK--THLTSLKTKFPAEQYY 85
           V     +   IL+LL       GFQD P   + A+  FST +  TH ++L   F    Y+
Sbjct: 202 VDHFYYSTYHILSLLC---PKCGFQDXPNTYI-AKCLFSTREDSTHFSTLLVLFSLHFYF 369

Query: 86  RFHEHW 91
            F  HW
Sbjct: 370 SFDFHW 387
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|82899408|ref|XP_894898.1| PREDICTED: TAO kinase 3
isoform 1 [Mus musculus]
         (898 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

18921                                                                 177   2e-44
13212                                                                 169   4e-42
12721                                                                 159   4e-39
19094                                                                 118   7e-38
00300                                                                 140   2e-33
14420                                                                 133   4e-31
13592                                                                 131   1e-30
01707                                                                 102   5e-22
01756                                                                  95   1e-19
01718                                                                  95   1e-19
06405                                                                  92   1e-18
01060                                                                  90   5e-18
04591                                                                  86   7e-17
29581                                                                  85   2e-16
14126                                                                  84   3e-16
00392                                                                  80   4e-15
37602                                                                  75   5e-14
19301                                                                  74   3e-13
03240                                                                  71   2e-12
30755                                                                  70   3e-12
09007                                                                  69   8e-12
00715                                                                  68   2e-11
18484                                                                  67   3e-11
14116                                                                  65   1e-10
15910                                                                  65   1e-10
11780                                                                  65   2e-10
21808                                                                  64   2e-10
19761                                                                  64   3e-10
09606                                                                  64   3e-10
31885                                                                  63   4e-10
01392                                                                  63   4e-10
04852                                                                  62   8e-10
21079                                                                  62   9e-10
01966                                                                  57   1e-09
04138                                                                  61   2e-09
07291                                                                  60   5e-09
21433                                                                  59   9e-09
27546                                                                  56   8e-08
13066                                                                  55   9e-08
03508                                                                  55   1e-07
28638                                                                  55   1e-07
26560                                                                  54   3e-07
17253                                                                  54   3e-07
28157                                                                  53   6e-07
21210                                                                  52   8e-07
07836                                                                  52   9e-07
27405                                                                  52   1e-06
17975                                                                  51   2e-06
12672                                                                  49   9e-06
12786                                                                  49   9e-06
14477                                                                  48   2e-05
07940                                                                  47   3e-05
32691                                                                  47   3e-05
18996                                                                  45   1e-04
06358                                                                  45   1e-04
17516                                                                  44   2e-04
25019                                                                  44   3e-04
02638                                                                  44   4e-04
32359                                                                  42   8e-04
13840                                                                  41   0.002
20640                                                                  40   0.005
17300                                                                  39   0.011
32000                                                                  39   0.012
18663                                                                  36   0.059
11185                                                                  36   0.059
00486                                                                  36   0.066
07833                                                                  36   0.082
31489                                                                  36   0.085
16708                                                                  34   0.20 
37063                                                                  34   0.21 
08294                                                                  33   0.43 
31789                                                                  33   0.59 
11516                                                                  33   0.63 
00394                                                                  32   1.0  
18481                                                                  32   1.1  
11404                                                                  32   1.2  
29360                                                                  32   1.7  
26009                                                                  31   1.9  
32957                                                                  31   2.0  
29011                                                                  31   2.2  
30599                                                                  30   3.7  
09201                                                                  29   7.6  
21800                                                                  29   9.3  
>18921
          Length = 697

 Score =  177 bits (449), Expect = 2e-44,   Method: Composition-based stats.
 Identities = 95/213 (44%), Positives = 129/213 (60%), Gaps = 5/213 (2%)
 Frame = +2

Query: 20  PEELFIDLHEIGHGSFGAVYFATNAHTNEVVAVKKMSYSGKQTHEKWQDILKEVKFLQQL 79
           PE++F  L ++G GS+G+V+ + +  T +V+A+K++           Q+I+KE+  +QQ 
Sbjct: 23  PEDVFDILGKLGEGSYGSVFKSLHKETGQVLAIKQVP-----VDTDLQEIIKEISIMQQC 187

Query: 80  KHPNTIEYKGCYLKEHTAWLVMEYC-LGSASDLLEVHKKPLQEVEIAAITHGALQGLAYL 138
                ++Y G Y K    W+VMEYC  GS SD++ +  K L E EIA I +  L+GL YL
Sbjct: 188 DSKYIVKYYGSYFKNTDLWIVMEYCGAGSVSDIMRLRNKTLVEREIATILYYTLKGLXYL 367

Query: 139 HFHSLIHRDIKAGNILLTEPGQVKLADFGSASMASPA----NSFVGTPYWMAPEVILAMD 194
           H    IHRDIKAGNILL   G  KLADFG A   +      N+ +GTPYWMAPEVI    
Sbjct: 368 HSRRKIHRDIKAGNILLNNEGHAKLADFGVAGQLTDTMAKRNTVIGTPYWMAPEVI---Q 538

Query: 195 EGQYDGKVDIWSLGITCIELAERKPPLFNMNAM 227
           E  YD   DIWSLGIT +E+AE KPP+   + +
Sbjct: 539 EIGYDCVADIWSLGITALEMAEGKPPVMETSIL 637
>13212
          Length = 1067

 Score =  169 bits (428), Expect = 4e-42,   Method: Compositional matrix adjust.
 Identities = 88/203 (43%), Positives = 123/203 (60%), Gaps = 9/203 (4%)
 Frame = -1

Query: 106  GSASDLLEVHKKPLQEVEIAAITHGALQGLAYLHFHSLIHRDIKAGNILLTEPGQVKLAD 165
            G+   ++   +KP+ E +I  + H     L +LH H +IHRDIKAGN+LLT  G+VKLAD
Sbjct: 1028 GALDSIMVDLEKPMTEAQICYVCHEMCMALDFLHRHHVIHRDIKAGNVLLTIDGEVKLAD 849

Query: 166  FGSASMASPA----NSFVGTPYWMAPEVILA--MDEGQYDGKVDIWSLGITCIELAERKP 219
            FG ++  +      ++F+GTPYWMAPEV+L   + +  YD K DIWSLG+T IE A+ +P
Sbjct: 848  FGVSAKNTQTQQKRDTFIGTPYWMAPEVVLCETLKDTPYDFKADIWSLGVTLIEFAQIEP 669

Query: 220  PLFNMNAMSALYHIAQNDSPTLQ-SREWTDSFRRFVDYCLHKIPQERPAAVELLRHDFIR 278
            P   M+ M  L  I ++D PTL+  ++WT  F+ F+  CL K P  RP A ELL H F++
Sbjct: 668  PNKEMHPMRVLIKIHKSDPPTLEKPKKWTKLFKDFIAKCLVKDPNLRPTAAELLEHPFMK 489

Query: 279  RERPP--KVLIDLIQRTKDAVRE 299
            R        + DLI  +K  V E
Sbjct: 488  RATATDKAAICDLIMESKAEVVE 420
>12721
          Length = 821

 Score =  159 bits (403), Expect = 4e-39,   Method: Compositional matrix adjust.
 Identities = 95/256 (37%), Positives = 140/256 (54%), Gaps = 6/256 (2%)
 Frame = +1

Query: 19  DPEELFIDLHEIGHGSFGAVYFATNAHTNEVVAVKKMSYSGKQTHEKWQDILKEVKFLQQ 78
           DP     D  +IG GS G V  AT+    ++ AVKKM    +Q  E    +  EV  ++ 
Sbjct: 79  DPRTFLDDFMKIGEGSTGIVCIATSRDGRQM-AVKKMDLRKQQRREL---LFNEVVVMRD 246

Query: 79  LKHPNTIEYKGCYLKEHTAWLVMEYCLGSA-SDLLEVHKKPLQEVEIAAITHGALQGLAY 137
             HPN +E    YL     W+VME+  G A +D++  ++  + EV+IA +    L+ LA+
Sbjct: 247 YHHPNIVEMYNSYLVNDELWVVMEFMEGGALTDIVTNNR--MDEVQIATVCRACLKALAF 420

Query: 138 LHFHSLIHRDIKAGNILLTEPGQVKLADFGSASMAS----PANSFVGTPYWMAPEVILAM 193
           LH + +IHRDIK+ +ILL+  G+VKL DFG  +  +       S VGTPYWMAPEVI  +
Sbjct: 421 LHANGVIHRDIKSDSILLSHDGKVKLXDFGFCAQVTQDLQKRKSLVGTPYWMAPEVISRL 600

Query: 194 DEGQYDGKVDIWSLGITCIELAERKPPLFNMNAMSALYHIAQNDSPTLQ-SREWTDSFRR 252
               Y  +VDIWSLGI  +E+ + +PP FN   + A+  I     P L+ + + +   + 
Sbjct: 601 ---PYGPEVDIWSLGIMVMEMIDAEPPFFNEPPLQAMRRIRDMPPPKLRNTHKISPRLQG 771

Query: 253 FVDYCLHKIPQERPAA 268
           F+D  L + P +R  A
Sbjct: 772 FIDRMLVRDPHQRATA 819
>19094
          Length = 898

 Score =  118 bits (295), Expect(2) = 7e-38,   Method: Composition-based stats.
 Identities = 63/115 (54%), Positives = 73/115 (63%), Gaps = 4/115 (3%)
 Frame = +1

Query: 106 GSASDLLEVHKKPLQEVEIAAITHGALQGLAYLHFHSLIHRDIKAGNILLTEPGQVKLAD 165
           GS SD++ +  K L E EIA I +  L+GL YLH    IHRDIKAGNILL   G  KLAD
Sbjct: 10  GSVSDIMRLRNKTLVEREIATILYYTLKGL*YLHSRRKIHRDIKAGNILLNNEGHAKLAD 189

Query: 166 FGSASMASPA----NSFVGTPYWMAPEVILAMDEGQYDGKVDIWSLGITCIELAE 216
           FG A   +      N+ +GTPYWMAPEVI    E  YD   DIWSLGIT +E+AE
Sbjct: 190 FGVAGQLTDTMAKRNTVIGTPYWMAPEVI---QEIGYDCVADIWSLGITALEMAE 345

 Score = 58.5 bits (140), Expect(2) = 7e-38,   Method: Compositional matrix adjust.
 Identities = 28/79 (35%), Positives = 46/79 (58%), Gaps = 1/79 (1%)
 Frame = +3

Query: 218 KPPLFNMNAMSALYHIAQNDSPTL-QSREWTDSFRRFVDYCLHKIPQERPAAVELLRHDF 276
           KPP  +++ M A++ I     P+  Q  +W+  F  FV  CL K P+ R  AV+LL+HDF
Sbjct: 348 KPPYGDIHPMRAIFMIPTKPPPSFRQPDKWSTEFIDFVSKCLVKNPENRATAVDLLQHDF 527

Query: 277 IRRERPPKVLIDLIQRTKD 295
           I++    ++L  +I+  K+
Sbjct: 528 IKKAEACEILQAMIREAKE 584
>00300
          Length = 2318

 Score =  140 bits (354), Expect = 2e-33,   Method: Compositional matrix adjust.
 Identities = 84/259 (32%), Positives = 131/259 (50%), Gaps = 8/259 (3%)
 Frame = -1

Query: 28   HEIGHGSFGAVYFATNAHTNEVVAVKKMSYSGKQTHEKWQDILKEVKFLQQLKHPNTIEY 87
            ++IG G FG VY A N  T E++A+K+M +      ++ +++  E+K  + ++H N ++Y
Sbjct: 1640 NKIGEGQFGKVYTAVNMSTGELMALKEMKFQPNDL-QQLREMCDEIKIFEGIQHENLVKY 1464

Query: 88   KGCYLKEHTAWLVMEYCLGSASDLLEVHKKPLQEVEIAAITHGALQGLAYLHFHSLIHRD 147
             G  + +    + MEYC      + E  K  L E  I   T   +  + +LH +S++HRD
Sbjct: 1463 YGVEVHKDEMLMFMEYC--DTGTIEEAAKMGLPEYLIRRYTREIVLAVNHLHENSIVHRD 1290

Query: 148  IKAGNILLTEPGQVKLADFGSA-------SMASPANSFVGTPYWMAPEVILAMDEGQYDG 200
            IK  NI LT  G VKL DFG +       +M    ++ VGT  +MAPEV    D+G Y  
Sbjct: 1289 IKGANIFLTSNGHVKLGDFGCSVKLKSHTTMPGEFHNLVGTTAYMAPEVFTQNDQGGYGR 1110

Query: 201  KVDIWSLGITCIELAERKPPLFNM-NAMSALYHIAQNDSPTLQSREWTDSFRRFVDYCLH 259
              DIWSLG   IE+A  K P  ++ N    +Y +     P +      +  + F+D  + 
Sbjct: 1109 AADIWSLGCVVIEMATGKRPWHDLDNNYQIMYKVGIGHKPAVPDSLSVEG-KHFLDLIMC 933

Query: 260  KIPQERPAAVELLRHDFIR 278
              P +R  A +LL H F +
Sbjct: 932  HDPAQRALASQLLDHTFTK 876
>14420
          Length = 528

 Score =  133 bits (334), Expect = 4e-31,   Method: Composition-based stats.
 Identities = 74/167 (44%), Positives = 100/167 (59%), Gaps = 5/167 (2%)
 Frame = +2

Query: 69  ILKEVKFLQQLKHPNTIEYKGCYLKEHTAWLVMEYCLG-SASDLLEVHKKPLQEVEIAAI 127
           I+ E+  +++ ++PN + Y   YL     W+VME+  G S +D+  V +  + E +IAA+
Sbjct: 41  IINEILVMRENQNPNIVNYLDSYLVGEELWVVMEFLAGGSLTDV--VTETCMDEGQIAAV 214

Query: 128 THGALQGLAYLHFHSLIHRDIKAGNILLTEPGQVKLADFGSASMASPANS----FVGTPY 183
               LQ L +LH + +IHRDIK+ NILL   G VKL DFG  +  SP  S     VGTPY
Sbjct: 215 CRECLQALEFLHENQVIHRDIKSDNILLGMDGSVKLTDFGFCAQLSPEQSKRSTMVGTPY 394

Query: 184 WMAPEVILAMDEGQYDGKVDIWSLGITCIELAERKPPLFNMNAMSAL 230
           WMAPEV+      QY   VDIWSLG+ CIE+ E +PP  N N + AL
Sbjct: 395 WMAPEVV---TRKQYGPTVDIWSLGVMCIEMIEGEPPYLNENPLRAL 526
>13592
          Length = 980

 Score =  131 bits (329), Expect = 1e-30,   Method: Compositional matrix adjust.
 Identities = 87/266 (32%), Positives = 137/266 (51%), Gaps = 14/266 (5%)
 Frame = +2

Query: 30  IGHGSFGAVYFATNAHTNEVVAVKKMSYSGKQTHEKWQDILKEVKFLQQLKHPNTIEYKG 89
           IG G FG VY A N +T E++A+K+++    +T    +++ +E+K L+ +KH N + Y G
Sbjct: 8   IGQGRFGKVYTAVNNNTGELMAMKEIAIQPGET-RALKNVAEELKILEGIKHKNLVRYYG 184

Query: 90  CYLKEHTAWLVMEYCL-GSASDLLEVHKKPLQEVEIAAITHGALQGLAYLHFHSLIHRDI 148
             +      + ME C  G+   L+E+    L E      T   L G+A LH H ++HRDI
Sbjct: 185 IEVHREELLIFMELCSEGTLESLVEL-TGGLPEALSRRFTAQLLSGVAELHKHGIVHRDI 361

Query: 149 KAGNILLTEPG-QVKLADFGSA-------SMASPANSFVGTPYWMAPEVILAMDEGQYDG 200
           K  NI L +    +KL DFGSA       ++      +VGT  +MAPEV    +   +  
Sbjct: 362 KTANIFLVDGSNSLKLGDFGSAVKIQAHTTVPGELQGYVGTQAYMAPEVFTKTNSDGHGR 541

Query: 201 KVDIWSLGITCIELAERKPPL--FNMNAMSALYHIAQND---SPTLQSREWTDSFRRFVD 255
             DIWS+G   +E+A  K P   F+ N    ++ +   +   +P   S+E  D    F+D
Sbjct: 542 LADIWSVGCVVVEMASGKRPWAQFDSN-FQIMFKVGMGEKPQAPESLSQEGHD----FID 706

Query: 256 YCLHKIPQERPAAVELLRHDFIRRER 281
           +CL   P++R +A+ELL  +F +  R
Sbjct: 707 HCLQHDPKQRLSAIELLEQNFCKSGR 784
>01707
          Length = 757

 Score =  102 bits (255), Expect = 5e-22,   Method: Composition-based stats.
 Identities = 65/200 (32%), Positives = 110/200 (55%), Gaps = 4/200 (2%)
 Frame = +1

Query: 19  DPEELFIDLHEIGHGSFGAVYFATNAHTNEVVAVKKMSYSGKQTHEKWQDILKEVKFLQQ 78
           D  E +  + +IG GS+G V+   N  T+++VA+KK   S      K +  ++E++ L+Q
Sbjct: 55  DRMEKYEKIGKIGEGSYGVVFKCRNKETSQLVAIKKFVESEDDPLIK-KIAMREIRMLKQ 231

Query: 79  LKHPNTIEYKGCYLKEHTAWLVMEYCLGSASDLLEVHKKPLQEVEIAAITHGALQGLAYL 138
           LKHPN +     + ++    LV +Y   +  + L+ + + L E  +  I +  L  + + 
Sbjct: 232 LKHPNLVRLIEVFRRKKRLHLVFDYVDHTLLNELDRYPRGLPEPMVKRIIYQTLLAVNFC 411

Query: 139 HFHSLIHRDIKAGNILLTEPGQVKLADFGSAS-MASPANS---FVGTPYWMAPEVILAMD 194
           H ++ IHRD+K  NIL+T  GQVKL DFG A  +  P +    +V T ++ APE+++   
Sbjct: 412 HQYNTIHRDVKPENILITRQGQVKLCDFGFARILTGPGDEYTDYVATRWYRAPELLVG-- 585

Query: 195 EGQYDGKVDIWSLGITCIEL 214
           + QY   VD+W++G    EL
Sbjct: 586 DTQYGPPVDVWAIGCVFAEL 645
>01756
          Length = 1858

 Score = 95.1 bits (235), Expect = 1e-19,   Method: Compositional matrix adjust.
 Identities = 67/208 (32%), Positives = 104/208 (50%), Gaps = 15/208 (7%)
 Frame = -3

Query: 27   LHEIGHGSFGAVYFATNAHTNEVVAVKKMSYSGKQTHEKWQDILKEVKFLQQLKHPNTIE 86
            L +IG G+FG V+ A    T +VVA+KK+    ++        L+E+K LQ L H N ++
Sbjct: 1727 LAKIGQGTFGEVFKARCKKTKQVVAMKKVLMDNEKEGFP-ITALREIKILQLLNHENVVD 1551

Query: 87   Y-KGCYLKEHTA-------WLVMEYCLGSASDLLEVHKKPLQEVEIAAITHGALQGLAYL 138
              + C  K  +A       +LV E+C    + LL          EI  +    + GL Y+
Sbjct: 1550 LIEICSTKATSANRYKSMFYLVFEFCEHDLAGLLSNMSVVFNLPEIKEVMKQLMNGLYYI 1371

Query: 139  HFHSLIHRDIKAGNILLTEPGQVKLADFG-----SASMASP--ANSFVGTPYWMAPEVIL 191
            H + ++HRD+KA NIL+T+ G +KLADFG     S ++  P    + V T ++  PE++L
Sbjct: 1370 HRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRVVTLWYRPPELLL 1191

Query: 192  AMDEGQYDGKVDIWSLGITCIELAERKP 219
               +  Y   +D W  G    E+  R P
Sbjct: 1190 G--DRNYSTAIDQWGAGCIMAEMWTRNP 1113
>01718
          Length = 959

 Score = 94.7 bits (234), Expect = 1e-19,   Method: Compositional matrix adjust.
 Identities = 76/259 (29%), Positives = 128/259 (49%), Gaps = 15/259 (5%)
 Frame = +3

Query: 29  EIGHGSFGAVYFATNAHTNEVVAVKKMSYSGKQTHEKWQDILKEVKFLQQLKHPNTIEYK 88
           +IG G F  V+  T+  T +V+A+K  + +  +      ++L+EV+ L +L+H N + + 
Sbjct: 168 KIGAGFFSEVFKVTHRITGQVMALKMNTMTSNR-----HNMLREVQLLNRLQHANILRFM 332

Query: 89  GCYLKEHTAWLVMEYCL-GSASDLLEVHKKPLQEVEIAAITHGALQGLAYLHFHSLIHRD 147
           G  + E     + EY   G+   LLE   + L   +   +T G  +GL YLH    IHRD
Sbjct: 333 GVCVHEGQLHALTEYIPSGNLEQLLEKKDEELPWTQRIQLTLGLARGLDYLHSTRFIHRD 512

Query: 148 IKAGNILL----TEPGQVKLADFGSAS-MASPAN----SFVGTPYWMAPEVILAMDEGQY 198
           + + NIL+           +ADFG A+ +  P +      VG+PYWMAPEV   ++   Y
Sbjct: 513 LTSKNILIRREDNHGYHAVIADFGLATKIPDPLDKEKLPTVGSPYWMAPEV---LNGHFY 683

Query: 199 DGKVDIWSLGITCIELAERKPP----LFNMNAMSALYHIAQNDSPTLQSREWTD-SFRRF 253
           + + D++S+GI   E+  R P     +  MN     Y +A ++  +    ++   +F+  
Sbjct: 684 NERADLFSVGIIMCEITARIPADPDIMPRMNNFGVDY-VALSEMISYCPLDYLQLAFK-- 854

Query: 254 VDYCLHKIPQERPAAVELL 272
              C    PQ+RP  VE++
Sbjct: 855 ---CCQVDPQKRPRGVEII 902
>06405
          Length = 1965

 Score = 91.7 bits (226), Expect = 1e-18,   Method: Compositional matrix adjust.
 Identities = 65/215 (30%), Positives = 108/215 (50%), Gaps = 9/215 (4%)
 Frame = +1

Query: 28  HEIGHGSFGAVYFATNAHTNEVVAVKKMSYSGKQTHEKWQDILKEVKFLQQLKHPNTIEY 87
           H +G G +G VY A     N++VAVK +    K+      D L+E   ++++KHPN ++ 
Sbjct: 277 HRLGGGQYGDVYEAMWKRYNKIVAVKTL----KEDTMALNDFLEEAAIMKEMKHPNLVQL 444

Query: 88  KGCYLKEHTAWLVMEYCL-GSASDLLEVHKKPLQEVEIAAITHGALQ---GLAYLHFHSL 143
            G   +E   ++V E+   G+  D L    +  +E    A+ + A Q   G+AYL   + 
Sbjct: 445 LGVCTREPPFYIVTEFMPHGNLLDYLRSSTR--EENGPTALMYMATQIASGMAYLETKNF 618

Query: 144 IHRDIKAGNILLTEPGQVKLADFGSASMA--SPANSFVGTPY---WMAPEVILAMDEGQY 198
           IHRD+ A N L+ +   VK+ADFG A +       + +G  +   W APE  LA +  ++
Sbjct: 619 IHRDLAARNCLVADSNMVKVADFGLARLMKDDTYTAHIGAKFPIKWTAPEG-LAFN--RF 789

Query: 199 DGKVDIWSLGITCIELAERKPPLFNMNAMSALYHI 233
             + DIW+ G+   ELA      +    ++ +YH+
Sbjct: 790 STRSDIWAFGVLLWELATYGMSPYPGVELTEVYHL 894
>01060
          Length = 1800

 Score = 89.7 bits (221), Expect = 5e-18,   Method: Compositional matrix adjust.
 Identities = 65/247 (26%), Positives = 121/247 (48%), Gaps = 10/247 (4%)
 Frame = +1

Query: 26  DLHEIGHGSFGAVYFATNAHTNEVVAVKKMSYSGKQTHEKWQDILKEVKFLQQLKHPNTI 85
           D  +IG G++G VY   +  T   +A+KK+   G +        ++E+  L++L+H N +
Sbjct: 85  DFQKIGEGTYGVVYKCRHRATGRKLAMKKIRLRGSEDGVP-SSAIREIAMLRELRHTNIV 261

Query: 86  EYKGCYLKEHTAWLVMEYCLGSASDL-LEVHKKP----LQEVEIAAITHGALQGLAYLHF 140
             +   +++   +LV E+    + DL + + K P    L    + +     + G+ + H 
Sbjct: 262 CLEDVIMEDERLFLVFEFL---SMDLKMYIDKFPEGVVLDRRLVKSYVFQIVTGIXFCHQ 432

Query: 141 HSLIHRDIKAGNILLTEPGQVKLADFGSA-SMASPANSF---VGTPYWMAPEVILAMDEG 196
             ++HRD+K  N+L+   G +K+ADFG A + A P  ++   V T ++ APE++  M   
Sbjct: 433 RRIVHRDLKPQNLLINHTGAIKIADFGMARTFALPVRAYTHEVVTLWYRAPEIL--MGAS 606

Query: 197 QYDGKVDIWSLGITCIELAERKPPLFNMNAMSALYHIAQ-NDSPTLQSREWTDSFRRFVD 255
           +Y   VD+WS+G    ++  R P     + +  L+ I +   +PT Q+  W +       
Sbjct: 607 KYSTPVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIFRIIGTPTEQT--WPE------- 759

Query: 256 YCLHKIP 262
              HK+P
Sbjct: 760 --FHKLP 774
>04591
          Length = 1117

 Score = 85.9 bits (211), Expect = 7e-17,   Method: Compositional matrix adjust.
 Identities = 55/161 (34%), Positives = 85/161 (52%), Gaps = 11/161 (6%)
 Frame = -2

Query: 70   LKEVKFLQQLKHPNTIEYK-------GCYLK-EHTAWLVMEYCLGSASDLLEVHKKPLQE 121
            L+E+K LQQL+H N ++ +       G Y + + T +L+ EYC    + LL   +     
Sbjct: 1077 LREIKILQQLEHENVVQLQEICHTQAGPYNRYKSTFYLIFEYCDYDLAGLLNNLRVKFSL 898

Query: 122  VEIAAITHGALQGLAYLHFHSLIHRDIKAGNILLTEPGQVKLADFGSASMASPANSF--- 178
             +   +    L GL Y+H   ++HRDIKA NILLT  G +KLADFG +     +      
Sbjct: 897  ADKKNLMSQLLNGLFYIHTKQILHRDIKAANILLTRDGVLKLADFGLSRPWVKSKRLTNR 718

Query: 179  VGTPYWMAPEVILAMDEGQYDGKVDIWSLGITCIELAERKP 219
            V T ++  PE++L   E +Y  ++D+W +G    E+  RKP
Sbjct: 717  VVTLWYRPPELLLG--EREYGPEIDMWGVGCIMAEMWSRKP 601
>29581
          Length = 1278

 Score = 84.7 bits (208), Expect = 2e-16,   Method: Compositional matrix adjust.
 Identities = 52/151 (34%), Positives = 78/151 (51%), Gaps = 6/151 (3%)
 Frame = -2

Query: 75   FLQQLKHPNTIEYKGCYLKEH--TAWLVMEYCLGSASDLLEVHKKPLQEVEIAAITHGAL 132
            FL  L+H N ++ +   + +   + +LVMEYC    + LL+    P  E ++  I    L
Sbjct: 1196 FLLNLRHQNIVQLQEVVVGKSLDSLFLVMEYCEQDLASLLDNMPAPFSESQVKCIVLQLL 1017

Query: 133  QGLAYLHFHSLIHRDIKAGNILLTEPGQVKLADFGSASMAS----PANSFVGTPYWMAPE 188
            +GL YLH   +IHRD+K  N+L+T+ G VK+ADFG A        P    V T ++ APE
Sbjct: 1016 KGLRYLHEAFIIHRDLKVSNLLMTDKGCVKIADFGLARNYGKPQKPMTPKVVTLWYRAPE 837

Query: 189  VILAMDEGQYDGKVDIWSLGITCIELAERKP 219
            ++       +   +D+WS G    EL   KP
Sbjct: 836  LLFG--SKTHSTAIDMWSAGCILGELLGHKP 750
>14126
          Length = 1265

 Score = 83.6 bits (205), Expect = 3e-16,   Method: Compositional matrix adjust.
 Identities = 64/215 (29%), Positives = 109/215 (50%), Gaps = 13/215 (6%)
 Frame = +3

Query: 17  KDDPEELFIDLHEIGHGSFGAVYFATNAHT-NEVVAVKKMSYSGKQTHEKWQDILKEVKF 75
           +D  E+ + ++  IG+G++G VY A +     E VA+K++  +  +       I +E+  
Sbjct: 174 RDSTEQKYEEVAVIGNGAYGTVYKARDLRNQGEFVAMKRIRLNNTEEGMPMMAI-REISM 350

Query: 76  LQQLK---HPNTI-----EYKGCYLKEHTAWLVMEYCLGSASDLLEVHKKP-LQEVEIAA 126
           L+QL+   HPN +      +     +E    LV EY     +  L     P L    I  
Sbjct: 351 LKQLEQYEHPNVVRLLDVSHNTITDREIRLNLVFEYIEHDLATYLAKCPSPGLGPDRIKD 530

Query: 127 ITHGALQGLAYLHFHSLIHRDIKAGNILLTEPGQVKLADFGSASMAS---PANSFVGTPY 183
           +    L G+ +LH + ++HRD+K  N+L+++ G++KLADFG A + S      + V T +
Sbjct: 531 LMLQLLNGVDFLHSNRIVHRDLKPQNLLISKDGRLKLADFGLARIYSFHMALTTVVVTLW 710

Query: 184 WMAPEVILAMDEGQYDGKVDIWSLGITCIELAERK 218
           + +PEV++   + +Y   VDIWS G    EL  R+
Sbjct: 711 YRSPEVLM---QAEYGTSVDIWSCGCIFAELFTRR 806
>00392
          Length = 668

 Score = 79.7 bits (195), Expect = 4e-15,   Method: Compositional matrix adjust.
 Identities = 58/172 (33%), Positives = 91/172 (52%), Gaps = 12/172 (6%)
 Frame = +3

Query: 72  EVKFLQQLKHPNTIEYKGCYLKEH------TAWLVMEYCL-GSASDLLEVHKKPLQEVEI 124
           E + L++L+HPN + +   Y +EH         LV E    G+    L+  KKP  ++ +
Sbjct: 81  EAEMLKELQHPNIVRFFD-YWEEHNHRNRKVIILVTELMTSGTLKTYLKRFKKPNVKI-L 254

Query: 125 AAITHGALQGLAYLHFHS--LIHRDIKAGNILLTEP-GQVKLADFGSASMA--SPANSFV 179
                  L+GL +LH  +  +IHRD+K  NI +T P G VK+ D G A++   S A S +
Sbjct: 255 KNWCRQVLKGLYFLHTRTPPVIHRDLKCDNIFITGPTGSVKIGDLGLATLKNQSFAKSVI 434

Query: 180 GTPYWMAPEVILAMDEGQYDGKVDIWSLGITCIELAERKPPLFNMNAMSALY 231
           GTP +MAPE    M E  YD  VD+++ G+  +E+A  + P    +  + +Y
Sbjct: 435 GTPEFMAPE----MYEEHYDEAVDVYAFGMCMLEMASSEYPYSECSNAAQIY 578
>37602
          Length = 804

 Score = 75.5 bits (184), Expect(2) = 5e-14,   Method: Composition-based stats.
 Identities = 45/103 (43%), Positives = 54/103 (52%), Gaps = 1/103 (0%)
 Frame = -1

Query: 85  IEYKGCYLKEHTAWLVMEYCLG-SASDLLEVHKKPLQEVEIAAITHGALQGLAYLHFHSL 143
           + Y   YL+    W+ MEYC G S  D+  V   PL E +IA +    L+GL YLH    
Sbjct: 330 VGYFDSYLRREKLWIAMEYCGGGSMQDIYHV-TGPLTEPQIAFVCRETLKGLHYLHRRGK 154

Query: 144 IHRDIKAGNILLTEPGQVKLADFGSASMASPANSFVGTPYWMA 186
           +HRDIK  NILLTE G VKLADF   S     N      +W A
Sbjct: 153 MHRDIKGANILLTEEGDVKLADFWRVSSNHSHNVQKKVFHWNA 25

 Score = 20.8 bits (42), Expect(2) = 5e-14,   Method: Composition-based stats.
 Identities = 7/7 (100%), Positives = 7/7 (100%)
 Frame = -3

Query: 183 YWMAPEV 189
           YWMAPEV
Sbjct: 22  YWMAPEV 2

 Score = 31.2 bits (69), Expect(2) = 0.20,   Method: Composition-based stats.
 Identities = 13/27 (48%), Positives = 17/27 (62%), Gaps = 4/27 (14%)
 Frame = -1

Query: 164 ADFGSASMASPA----NSFVGTPYWMA 186
           ADFG ++  +       SF+GTPYWMA
Sbjct: 747 ADFGVSAQITATMCKRKSFIGTPYWMA 667

 Score = 21.9 bits (45), Expect(2) = 0.20,   Method: Composition-based stats.
 Identities = 10/12 (83%), Positives = 10/12 (83%)
 Frame = -2

Query: 152 NILLTEPGQVKL 163
           NILLTE G VKL
Sbjct: 803 NILLTEEGDVKL 768
>19301
          Length = 712

 Score = 73.9 bits (180), Expect = 3e-13,   Method: Composition-based stats.
 Identities = 56/165 (33%), Positives = 89/165 (53%), Gaps = 7/165 (4%)
 Frame = +2

Query: 12  ADLFFKDD---PEELFIDLHEIGHGSFGAVYFATNAHTNEVVAVKKMSYSGKQTHEKWQD 68
           A+L  +DD   P E   DL  +G G+ GAV+        E VAVKK+           +D
Sbjct: 266 AELKQQDDWEIPFESITDLEWLGSGAQGAVFLGK--LCAEEVAVKKV-----------RD 406

Query: 69  ILK-EVKFLQQLKHPNTIEYKGCYLKEHTAWLVMEYCLGSASDLLEVHKKPLQEVEIAAI 127
           I + +++ L++L HPN I +KG   +     ++MEYC      L EV +   +E+  A +
Sbjct: 407 IKETDIRNLRKLNHPNIISFKGVCTQAPCYCIIMEYC--PYGQLYEVLRDG-KEIPPALV 577

Query: 128 THGALQ---GLAYLHFHSLIHRDIKAGNILLTEPGQVKLADFGSA 169
              + Q   G+ YLH H +IHRD+K+ N+L+ +   VK++DFG++
Sbjct: 578 LDWSKQIASGMNYLHSHKIIHRDLKSPNVLVAKNDVVKISDFGTS 712
>03240
          Length = 1683

 Score = 71.2 bits (173), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 60/265 (22%), Positives = 99/265 (37%), Gaps = 54/265 (20%)
 Frame = -3

Query: 23   LFIDLHEIGHGSFGAVYFATNAHTNEVVAVKKMSYSGKQTHEKWQDILKEVKFLQQLKHP 82
            +F  +  +G G+FG V       T  + A+K +  S      +   +  E   L +  + 
Sbjct: 1288 MFEKIKTLGVGAFGEVSLCRKNDTGMLYAMKTLRKSDVLKRNQVAHVKAERDILAEADNE 1109

Query: 83   NTIEYKGCYLKEHTAWLVMEYCLGSASDLL------EVHKKPLQEVEIAAITHGALQGLA 136
              ++    +   +  + VM+Y  G   DL+      E+  +PL    +A +    +Q + 
Sbjct: 1108 WVVKLYYSFQDHNYLYFVMDYVPGG--DLMGLLIRMEILDEPLARFYVAEL----VQAIE 947

Query: 137  YLHFHSLIHRDIKAGNILLTEPGQVKLADFGSAS-------------------------- 170
             +H    IHRDIK  NIL+   G +KL DFG  +                          
Sbjct: 946  SVHRMGFIHRDIKPDNILIDRNGHIKLTDFGLCTGFRWTHNSKYYQRDGTHARQDSMEVK 767

Query: 171  ----------MASP------------ANSFVGTPYWMAPEVILAMDEGQYDGKVDIWSLG 208
                      +  P            A+S VGTP ++APEV+  +  G Y    D WS+G
Sbjct: 766  CQLDEQCQCEILKPLERRRKREQRCLAHSLVGTPNYIAPEVLSRL--GGYTSVCDWWSVG 593

Query: 209  ITCIELAERKPPLFNMNAMSALYHI 233
            +   E+    PP +        Y +
Sbjct: 592  VILFEMLVGHPPFYANTPAETQYKV 518
>30755
          Length = 1137

 Score = 70.1 bits (170), Expect = 3e-12,   Method: Compositional matrix adjust.
 Identities = 36/101 (35%), Positives = 55/101 (54%), Gaps = 6/101 (5%)
 Frame = +2

Query: 129 HGA--LQGLAYLHFHSLIHRDIKAGNILLTEPGQVKLADFG----SASMASPANSFVGTP 182
           +GA  +  L YLH   +I+RD+K  N+LL + G +K+ADFG      +      +F GTP
Sbjct: 47  YGAEIISALGYLHSQGIIYRDLKLENLLLDKDGHIKVADFGLCKEDITYGRTTKTFCGTP 226

Query: 183 YWMAPEVILAMDEGQYDGKVDIWSLGITCIELAERKPPLFN 223
            ++APEV   +D+  Y   VD W  G+   E+   + P +N
Sbjct: 227 EYLAPEV---LDDNDYGRAVDWWGTGVVMYEMICGRLPFYN 340
>09007
          Length = 1440

 Score = 68.9 bits (167), Expect = 8e-12,   Method: Compositional matrix adjust.
 Identities = 65/263 (24%), Positives = 104/263 (39%), Gaps = 20/263 (7%)
 Frame = -1

Query: 30  IGHGSFGAVYFAT-NAHTNEVVAVKKMSYSGKQTHEKWQDILKEVKFLQQLKHPNTIEYK 88
           +G G FG V  A   A + E V V     S  + H+  Q+ LKE   +Q L H N +   
Sbjct: 855 LGQGHFGTVRQAIWTAESGEKVQVAVKCLSKDKIHKDGQEFLKETAIMQMLDHENIVRVY 676

Query: 89  GCYLKEHTAWLVMEYCLGSASDLLEVHKKPLQEVEIAA-----ITHGALQGLAYLHFHSL 143
           G  + ++ A +++   L     LLE  K+    V+ +       +     G++YL    L
Sbjct: 675 GVVM-DNGADIMLVTELAPMRSLLECVKEVSARVDFSVPRLCDFSQQVCDGMSYLESKRL 499

Query: 144 IHRDIKAGNILLTEPGQVKLADFGSASMASPANSFV---------GTPYWMAPEVILAMD 194
           +HRD+ A NILL    +VK++D G +        +              W APE    + 
Sbjct: 498 VHRDLAARNILLFSKSKVKISDVGVSGALGAGKEYYQSQQTIHLQNAVAWCAPESFRNL- 322

Query: 195 EGQYDGKVDIWSLGITCIELAERK-PPLFNMNAMSALYHIAQNDSPTLQSREWTD----S 249
              +    D+W+ G+   E       P   +N    +  +   D+P  Q  E  D     
Sbjct: 321 --CFSSASDVWAFGVLLWEFFTHGFQPWAGLNGQQIMEAV---DAPQSQRLEQPDLCPKE 157

Query: 250 FRRFVDYCLHKIPQERPAAVELL 272
           +   +  C  + PQ RP   +L 
Sbjct: 156 YYAVMLKCWEQEPQRRPTFSQLF 88
>00715
          Length = 1788

 Score = 67.8 bits (164), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 60/239 (25%), Positives = 106/239 (44%), Gaps = 39/239 (16%)
 Frame = +1

Query: 73  VKFLQQLKHPNTIEYKGC---YLKEHTAWLVMEYCLGSAS--DLLEVHKKPLQEVEIAAI 127
           + F   L+H N +   G    +  E  AWL MEY +G  +   +L  H+   Q+++ +  
Sbjct: 79  LAFRCGLRHVNVVSILGATSLHRFEDGAWLAMEY-VGPLNLQTILNDHQ---QDIDSSMR 246

Query: 128 THGALQ---GLAYLHFHSLIHRDIKAGNILLTEPGQVKLADFGSASMASPA--------- 175
              ALQ   GL YLH  +++H D+K  N LLT   ++++ADFG     +P          
Sbjct: 247 LSLALQMARGLHYLHSINIVHLDLKPANCLLTRDLKLRIADFGCCHQLTPTGLDMGEREG 426

Query: 176 -----------------NSFVGTPYWMAPEVILAMDEGQYDGKVDIWSLGITCIELAERK 218
                            N   GT  + APE++  +   Q   + D++SLGIT  ++  R+
Sbjct: 427 GMAGNELELTPVQGAWKNELAGTLAYRAPELLKGL---QPSVRSDVYSLGITLWQMCTRQ 597

Query: 219 PPLFNMNAMSALYHIAQND-----SPTLQSREWTDSFRRFVDYCLHKIPQERPAAVELL 272
            P   + A + +Y +   D      P+ +   +   FR     C  +  ++RP +++++
Sbjct: 598 GPYEGVPAHAVVYQVVSKDLRPCPPPSTEDDPFEVMFRDLYTQCWARRVEDRPTSLDVV 774
>18484
          Length = 635

 Score = 67.0 bits (162), Expect = 3e-11,   Method: Composition-based stats.
 Identities = 34/92 (36%), Positives = 51/92 (55%), Gaps = 4/92 (4%)
 Frame = +1

Query: 134 GLAYLHFHSLIHRDIKAGNILLTEPGQVKLADFG--SASMASPAN--SFVGTPYWMAPEV 189
           GL +LH   +I+RD+K  N++L   G +K+ADFG     M   A   +F GTP ++APE+
Sbjct: 79  GLFFLHDQGIIYRDLKLDNVMLDSEGHIKIADFGMCKEGMTGDATTRTFCGTPDYIAPEI 258

Query: 190 ILAMDEGQYDGKVDIWSLGITCIELAERKPPL 221
           +L      Y   VD W+ G+   E+   +PP 
Sbjct: 259 VLYQ---PYSKSVDWWAYGVLLFEMLAGQPPF 345
>14116
          Length = 1017

 Score = 65.5 bits (158), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 56/201 (27%), Positives = 84/201 (41%), Gaps = 12/201 (5%)
 Frame = -1

Query: 29  EIGHGSFGAV---YFATNAHTNEVVAVKKMSYSGKQTHEKWQDILKEVKFLQQLKHPNTI 85
           EIG G+FG V   +        +++   K  ++      + Q  L+E   ++   H N +
Sbjct: 615 EIGKGNFGCVKRGFLTLPEQKGDILVAVKTLHNNNPREIELQSFLQEALIMKDFHHSNVL 436

Query: 86  EYKGCYLKEHTAWLVMEYCLGSASDLLEVHKKPLQEVEIAAITHGA--LQGLAYLHFHSL 143
              G  L      LV+   +     L  +     Q      I +G    +G+ YL     
Sbjct: 435 TLIGICLNLDDMPLVVLPFMKHGDLLTYIRDDQHQPTIKDLIMYGVDIARGMDYLAGLKF 256

Query: 144 IHRDIKAGNILLTEPGQVKLADFGSA------SMASPANSFVGTPY-WMAPEVILAMDEG 196
           +HRD+ A N +L E   VK+ADFG A         S  N     P  WMA E   ++++G
Sbjct: 255 VHRDLAARNCMLDEDFHVKVADFGLARDIYEKEYYSSENKKAKLPVKWMALE---SLEKG 85

Query: 197 QYDGKVDIWSLGITCIELAER 217
            YD K D+WS G+   EL  R
Sbjct: 84  NYDSKTDVWSYGVVLWELLTR 22
>15910
          Length = 1361

 Score = 65.1 bits (157), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 35/100 (35%), Positives = 56/100 (56%), Gaps = 6/100 (6%)
 Frame = +2

Query: 132 LQGLAYLHFHSLIHRDIKAGNIL---LTEPGQVKLADFGSASMASP---ANSFVGTPYWM 185
           L G+ Y+H + ++HRD+K  N+L   +T+  ++KLADFG + +  P    ++  GTP + 
Sbjct: 494 LHGVQYIHANGVVHRDLKPENLLYECMTDDSKLKLADFGLSRIIEPEVQMSTVCGTPGYC 673

Query: 186 APEVILAMDEGQYDGKVDIWSLGITCIELAERKPPLFNMN 225
           APEV   +   +Y   VD+WS+G+    L     P F  N
Sbjct: 674 APEV---LKGDKYTPSVDMWSVGVIAYILLCGYEPFFAEN 784
>11780
          Length = 1713

 Score = 64.7 bits (156), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 50/167 (29%), Positives = 80/167 (47%), Gaps = 6/167 (3%)
 Frame = +3

Query: 30  IGHGSFGAVYFATNAHTNEVVAVKKMSYSGKQTHEKWQDILKEVKFLQQLKHPNTIEYKG 89
           IG G FG VY     +  + VA+K++    K      Q  L+E   +  L+H N +   G
Sbjct: 621 IGKGDFGDVY--KGMYRGQPVAIKQL----KDKDRGEQSFLQEASVMTSLRHDNLVRLIG 782

Query: 90  CYLKEHTAWLVMEYCL-GSASDLLEVHKKPL----QEVEIAAITHGALQGLAYLHFHSLI 144
             L E T +LV E+   G+  + L    + +     ++  A  T  A++   YL    L+
Sbjct: 783 VVLGE-TIFLVTEFMGKGNLVEYLRSRGRSVITKKDQINFATDTCAAME---YLESKRLV 950

Query: 145 HRDIKAGNILLTEPGQVKLADFGSASMASPANSFVGTPY-WMAPEVI 190
           HRD+ A N+L+ + G+ K++DFG A     + + V  P  W APE +
Sbjct: 951 HRDLAARNVLVHDDGKAKVSDFGLAKFGDFSQTSVKFPIKWTAPEAL 1091
>21808
          Length = 1011

 Score = 63.9 bits (154), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 46/153 (30%), Positives = 77/153 (50%), Gaps = 6/153 (3%)
 Frame = +1

Query: 67  QDILKEVKFLQQLKHPNTIEYKGCYLKEHTAWLVMEYCL-GSASDLLEVHKKPLQEVEIA 125
           +D L E + +++L+HP  I+      ++   +++ E    GS  + L+   + L+   + 
Sbjct: 67  KDFLAEAQIMKKLRHPKLIQLYAVCTQDDPIFIITELMKNGSLLEFLQGKGRVLKLPALI 246

Query: 126 AITHGALQGLAYLHFHSLIHRDIKAGNILLTEPGQVKLADFGSASMA--SPANSFVGTPY 183
            I      G+AYL   + IHRD+ A NIL+++   VK+ADFG A +       + VG  +
Sbjct: 247 DIGAQIACGMAYLESQNYIHRDLAARNILVSDNNTVKIADFGLARVIKEDEYEARVGARF 426

Query: 184 ---WMAPEVILAMDEGQYDGKVDIWSLGITCIE 213
              W APE   A +  ++  K D+WS GI   E
Sbjct: 427 PIKWTAPE---AANYNRFTIKSDVWSFGILLTE 516
>19761
          Length = 473

 Score = 63.5 bits (153), Expect = 3e-10,   Method: Composition-based stats.
 Identities = 42/133 (31%), Positives = 69/133 (51%), Gaps = 12/133 (9%)
 Frame = -3

Query: 134 GLAYLHFHS--LIHRDIKAGNILLTEPGQVKLADFGSA-SMASPAN---SFVGTPYWMAP 187
            L Y+H H+  ++HRD+K  NI +TE G V+L D G A  +  PA+   S VGT  +++P
Sbjct: 387 ALNYMHTHTPVILHRDLKPQNIYVTEKGDVRLGDLGLARKLTGPADFATSQVGTIMYLSP 208

Query: 188 EVILAMDEGQYDGKVDIWSLGITCIELAERKPPLFNMNAMSALYHIAQNDS------PTL 241
           E+   + +  Y+ K DIWSLG    ++  +K      + M  ++ + Q         P  
Sbjct: 207 EI---LSQQPYNSKSDIWSLGCVFYDITGKK----GSDEMGVMFLLVQVMGGRKLPLPDH 49

Query: 242 QSREWTDSFRRFV 254
            S+E+ D+  R +
Sbjct: 48  YSQEFRDTISRML 10
>09606
          Length = 1300

 Score = 63.5 bits (153), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 55/229 (24%), Positives = 89/229 (38%), Gaps = 27/229 (11%)
 Frame = -3

Query: 22   ELFIDLHEIGHGSFGAVYFATNAHTNEVVAVKKMSYSGKQTHEKWQDILKEVKFLQQLKH 81
            E F+   E+G G    +Y      T   VA+  +         K  ++   V+    + H
Sbjct: 1115 ENFVLYEELGKGEHSIIYKGRRKGTINFVAIHCIEKC------KRPEVTNTVRMTHDISH 954

Query: 82   PNTIEYKGCYLKEHTAWLVMEYCL-GSASDLLEVHKKPLQEVEIAAITHGALQGLAYLHF 140
            PN +++   Y   +  WLV+E C  GS +D+L      L E  I       + GL Y+H 
Sbjct: 953  PNVVQFHEWYETSNHLWLVVELCTGGSLADIL-AQDHHLPETSIRDFGIHLVTGLHYIHS 777

Query: 141  HSLIHRDIKAGNILLTEPGQVKLADFGSASM------------ASPANSF---------- 178
              ++  D++   +LL   G +K ADFG + +            A   + +          
Sbjct: 776  LGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEAGDQWNIQSAEEMMK 597

Query: 179  ----VGTPYWMAPEVILAMDEGQYDGKVDIWSLGITCIELAERKPPLFN 223
                 G+P +MAPEV    +        D+W+LG    E+    PP   
Sbjct: 596  QVPTSGSPTYMAPEVFQGAEPSIMS---DLWALGCVFYEMFSGHPPFLG 459
>31885
          Length = 529

 Score = 63.2 bits (152), Expect = 4e-10,   Method: Composition-based stats.
 Identities = 56/172 (32%), Positives = 87/172 (50%), Gaps = 11/172 (6%)
 Frame = -2

Query: 73  VKFLQQLKHPNTIEYKGCYLKEHTAWLVMEYCLGSASDLLEVHKKPLQEVEIAA------ 126
           V  L +L HP  +     +  E   ++V++  LG     L  H +  QEV          
Sbjct: 519 VDMLTRLDHPFLVNLWYAFQDEEDLFMVVDLFLGGD---LRYHMQ--QEVSFREDCVKFY 355

Query: 127 ITHGALQGLAYLHFHSLIHRDIKAGNILLTEPGQVKLADFGSASMASP---ANSFVGTPY 183
           +   AL  L YL    ++HRDIK  NILL E G   + DF  A+       A S  GT  
Sbjct: 354 LCQLALV-LDYLRSQKIVHRDIKPDNILLDEQGHCHVTDFNIATQLEDDELATSTSGTRP 178

Query: 184 WMAPEVI-LAMDEGQ-YDGKVDIWSLGITCIELAERKPPLFNMNAMSALYHI 233
           +MAPEV  +A++E + Y   VD WSLG++  EL +++ P F++++ ++L+ +
Sbjct: 177 YMAPEVYGVAINERRGYGFPVDWWSLGVSLFELLKKRRP-FSVHSNTSLHEM 25
>01392
          Length = 1806

 Score = 63.2 bits (152), Expect = 4e-10,   Method: Compositional matrix adjust.
 Identities = 56/196 (28%), Positives = 88/196 (44%), Gaps = 31/196 (15%)
 Frame = -1

Query: 119  LQEVEIAAITHGALQGLAYLHFHSLIHRDIKAGNIL---LTEPGQVKLADFGSASMASPA 175
            L E E + +     + L +LH   + HRD+K  NIL   L +   VK+ DF  AS  S  
Sbjct: 1800 LCEREASLVVRHIARALDFLHSKGIAHRDLKPENILCEHLDDVVPVKICDFDLASGISCD 1621

Query: 176  N---------SFVGTPYWMAPEVILAM--DEGQYDGKVDIWSLGITCIELAERKPPLFNM 224
                      + VG+  +MAPEV+ A   D   YD + D+WSLGI    +    PP +  
Sbjct: 1620 GDGTKTPELLTPVGSAEYMAPEVVDAWVGDSFSYDKRCDLWSLGIILYIMLCGYPPFYGQ 1441

Query: 225  --------------NAMSALYHIAQNDSPTLQSREWT---DSFRRFVDYCLHKIPQERPA 267
                          +    L++  Q+      S+EWT    S +  + + L + P++R +
Sbjct: 1440 CGEDCGWNRGEACHDCQDMLFNSIQDGHYKFPSQEWTSISSSAKDLIRHLLVREPRKRYS 1261

Query: 268  AVELLRHDFIRRERPP 283
            A ++L+H +I    PP
Sbjct: 1260 AADVLKHPWIC--TPP 1219
>04852
          Length = 1462

 Score = 62.4 bits (150), Expect = 8e-10,   Method: Compositional matrix adjust.
 Identities = 62/252 (24%), Positives = 105/252 (41%), Gaps = 44/252 (17%)
 Frame = +1

Query: 67  QDILKEVKFLQQLK----HPNTIEYKGCYLKEHTAWLVMEYCL-GSASDLLEVHKKPL-- 119
           QD ++E++ ++ +K    H N + + GC  +    W+++E+   G+  D LE  +  +  
Sbjct: 73  QDFVQELQVMKAVKKMGSHINIVNFLGCCTQGGPLWVIVEFAKNGNLRDFLESCRDGING 252

Query: 120 -------QEVEIAAITHGA---------------LQGLAYLHFHSLIHRDIKAGNILLTE 157
                  Q+      T G                 +G+ +L     IHRD+ A N+L+TE
Sbjct: 253 YGKFVSPQDPGWYTKTPGGHVIRRKNLLSYAFQIARGMEFLASRKCIHRDLAARNVLVTE 432

Query: 158 PGQVKLADFGSASMASPANSFVGT--PY-WMAPEVILAMDEGQYDGKVDIWSLGITCIEL 214
              +K+ADFG +          G   P  WMAPE +  M   +Y  K D+WS G+   E 
Sbjct: 433 EHVLKIADFGLSRTGDYYKKRSGGRLPVKWMAPEALFDM---RYTTKSDVWSFGVVLWE- 600

Query: 215 AERKPPLFNMNAMSALYHIAQNDSPTLQSREWTDSFR------------RFVDYCLHKIP 262
                 +F++  M   Y    N+   L S+   D++R              ++ C    P
Sbjct: 601 ------IFSLGGMP--YASIPNEE--LYSKLLDDAYRMPRPELASGNLYAIMERCWLNRP 750

Query: 263 QERPAAVELLRH 274
            +RP   +L+ H
Sbjct: 751 SDRPEFSQLVGH 786
>21079
          Length = 878

 Score = 62.0 bits (149), Expect = 9e-10,   Method: Composition-based stats.
 Identities = 43/139 (30%), Positives = 65/139 (46%), Gaps = 8/139 (5%)
 Frame = +1

Query: 81  HPNTIEYKGCYLKEHTAWLVMEYCLGSASDLLEVHKKP---LQEVEIAAITHGALQGLAY 137
           HP  +     +    T  LVME+    A +L E   +    L E +          G+ Y
Sbjct: 1   HPKLLMLWDAFEAPRTMVLVMEFV--GAGELFERVIRDDFVLTERDCVHFVRQICSGVGY 174

Query: 138 LHFHSLIHRDIKAGNILLTE--PGQVKLADFGSASMASPANS---FVGTPYWMAPEVILA 192
           +H  S++H D+K  N+L       Q+K+ DFG A    P +S     GTP ++APEV+  
Sbjct: 175 MHTQSILHLDLKPENVLCVSDNSNQIKIIDFGLARFYKPGDSLQVLFGTPEFIAPEVV-N 351

Query: 193 MDEGQYDGKVDIWSLGITC 211
            DE  +    D+WS+G+ C
Sbjct: 352 YDEINF--TTDMWSIGVIC 402
>01966
          Length = 1735

 Score = 57.4 bits (137), Expect(2) = 1e-09,   Method: Compositional matrix adjust.
 Identities = 40/156 (25%), Positives = 80/156 (51%), Gaps = 9/156 (5%)
 Frame = -1

Query: 46   TNEVVAVKKMSYSGKQTHEKWQDILKEVKFLQQLKHPNTIEYKGCYLKEHTAWLVMEYCL 105
            T   +A+KK+   G +        ++E+  L++L+H N +  +   +++   +LV E+  
Sbjct: 1639 TGRKLAMKKIRLRGSEDGVP-SSAIREIAMLRELRHTNIVCLEDVIMEDERLFLVFEFL- 1466

Query: 106  GSASDL-LEVHKKP----LQEVEIAAITHGALQGLAYLHFHSLIHRDIKAGNILLTEPGQ 160
              + DL + + K P    L    + +     + G+ + H   ++HRD+K  N+L+   G 
Sbjct: 1465 --SMDLKMYIDKFPEGVVLDRRLVKSYVFQIVTGINFCHQRRIVHRDLKPQNLLINHTGA 1292

Query: 161  VKLADFGSA-SMASPANSF---VGTPYWMAPEVILA 192
            +K+ADFG A + A P  ++   V T ++ APE+++ 
Sbjct: 1291 IKIADFGMARTFALPVRAYTHEVVTLWYRAPEILMG 1184

 Score = 23.9 bits (50), Expect(2) = 1e-09,   Method: Compositional matrix adjust.
 Identities = 8/23 (34%), Positives = 13/23 (56%)
 Frame = -3

Query: 197  QYDGKVDIWSLGITCIELAERKP 219
            +Y   VD+WS+G    ++  R P
Sbjct: 1178 KYSTPVDVWSIGTIFADMLIRTP 1110
>04138
          Length = 800

 Score = 61.2 bits (147), Expect = 2e-09,   Method: Composition-based stats.
 Identities = 55/208 (26%), Positives = 89/208 (42%), Gaps = 39/208 (18%)
 Frame = +1

Query: 126 AITHGALQGLAYLHFHSLIHRDIKAGNILLTEPGQVKLADFG-----SASMASPA--NSF 178
           +I   A + L Y+H + ++HRD+KA NIL+T+ G +KLADFG     S ++  P    + 
Sbjct: 25  SIC*AADERLYYIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNR 204

Query: 179 VGTPYWMAPEVILAMDEGQYDGKVDIWSLGITCIELAERKPPL---FNMNAMS------- 228
           V T ++  PE++L   +  Y   +D W  G    E+  R P +      N ++       
Sbjct: 205 VVTLWYRPPELLLG--DRNYSTAIDQWGAGCIMAEMWTRNPIMQGTTEQNQLTLITQLCG 378

Query: 229 -------------ALYHIAQNDSPTLQSREWTDSFRRFV---------DYCLHKIPQERP 266
                        ++YH  +      +     D F R +         +  L   P +R 
Sbjct: 379 SITPEVWPGVTQLSMYHQIKGALAAGRKNIIRDRFARILKDPYGLDLFERLLKMDPSQRI 558

Query: 267 AAVELLRHDFIRRERPPKVLIDLIQRTK 294
           +A E L HDF      PK L+ ++ R K
Sbjct: 559 SADEALNHDFFWVGVEPKSLVGVLSRLK 642
>07291
          Length = 833

 Score = 59.7 bits (143), Expect = 5e-09,   Method: Composition-based stats.
 Identities = 38/145 (26%), Positives = 69/145 (47%), Gaps = 7/145 (4%)
 Frame = +1

Query: 134 GLAYLHFHSLIHRDIKAGNILLTEPGQVKLADFGSASMASPANSFVG--TPY-----WMA 186
           G+AYL    ++HR++ A N ++TE G+++L+D+G      P + +    +P      WMA
Sbjct: 85  GMAYLQEVKVVHRNLAARNCIVTEDGRLQLSDYGVTGSLFPQSYYTADDSPARDLVKWMA 264

Query: 187 PEVILAMDEGQYDGKVDIWSLGITCIELAERKPPLFNMNAMSALYHIAQNDSPTLQSREW 246
           PE I   D   +  K D+W+ G+   EL  R    +     S+L    +      + ++ 
Sbjct: 265 PETI---DNFHFSSKSDVWAFGVVLWELLTRGITPYPDVENSSLLPYLKEGHRMKKPKQS 435

Query: 247 TDSFRRFVDYCLHKIPQERPAAVEL 271
            +     +  C ++ P++RP   EL
Sbjct: 436 PEPVYEMMTACWNESPEQRPDFAEL 510
>21433
          Length = 590

 Score = 58.9 bits (141), Expect = 9e-09,   Method: Composition-based stats.
 Identities = 38/91 (41%), Positives = 53/91 (58%), Gaps = 3/91 (3%)
 Frame = +2

Query: 134 GLAYLHFHSLIHRDIKAGNILLTEPGQVKLADFGSASMA--SPANSFVGTPYWMAPEVIL 191
            L Y H+  +IHRDIK  N+LL   G +K+ADFG +  A  S   +  GT  ++ PE++ 
Sbjct: 203 ALEYCHYRKVIHRDIKPENLLLGLKGDLKIADFGWSVHAPSSRRTTMCGTLDYLPPEMV- 379

Query: 192 AMDEGQ-YDGKVDIWSLGITCIELAERKPPL 221
              EG+ +D  VD+WSLG+ C E     PPL
Sbjct: 380 ---EGKTHDENVDLWSLGVLCYEFLVGTPPL 463
>27546
          Length = 426

 Score = 55.8 bits (133), Expect = 8e-08,   Method: Compositional matrix adjust.
 Identities = 35/101 (34%), Positives = 52/101 (51%), Gaps = 2/101 (1%)
 Frame = -1

Query: 71  KEVKFLQQLKHPNTIEYKGCYLKEHTAWLVMEYCLGSASDLLEVHKK--PLQEVEIAAIT 128
           +E++ L +L HPN I+      +    ++ M Y      D+L   KK  P+ E +     
Sbjct: 333 RELEILTRLDHPNIIQIHSILQRGPKIFIFMRY--AEKGDMLSHIKKTGPIDEAQTKVWF 160

Query: 129 HGALQGLAYLHFHSLIHRDIKAGNILLTEPGQVKLADFGSA 169
               + L YLH H + HRD+K  NILL++   VK+ADFG A
Sbjct: 159 FQMAKALQYLHSHDIAHRDLKCENILLSKRLNVKIADFGFA 37
>13066
          Length = 551

 Score = 55.5 bits (132), Expect = 9e-08,   Method: Composition-based stats.
 Identities = 43/148 (29%), Positives = 68/148 (45%), Gaps = 10/148 (6%)
 Frame = +3

Query: 71  KEVKFLQQLKHPNTIEYKGCYLKEHTAWLVMEYCLGSASDLLEVHKKP--LQEVEIAAIT 128
           +E+  L +L HP  I+      +    ++ M +      DLL   ++   ++E +     
Sbjct: 123 RELDLLTKLDHPYIIQIHSILQRXPKNFIFMRF--AERGDLLTYIQEVGFVKEKQAKIWF 296

Query: 129 HGALQGLAYLHFHSLIHRDIKAGNILLTEPGQVKLADFGSASMASP-------ANSFVGT 181
           +     L YLH + + HRD+K  NILL+    VKLADFG A            + ++ G+
Sbjct: 297 YQMTTALNYLHSYDVAHRDLKCENILLSSHFNVKLADFGFACACITESGEKYMSRTYCGS 476

Query: 182 PYWMAPEVILAMDEGQYDGKV-DIWSLG 208
             + APE++       Y  KV D WSLG
Sbjct: 477 AAYAAPEIVYG---APYAPKVADAWSLG 551
>03508
          Length = 1463

 Score = 55.1 bits (131), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 32/107 (29%), Positives = 55/107 (51%), Gaps = 4/107 (3%)
 Frame = +1

Query: 119 LQEVEIAAITHGALQGLAYLHFHSLIHRDIKAGNILLT-EPGQVKLADFGSASMASPA-- 175
             + +I    +  ++ L + H   ++HRD+K  N+++  E  +++L D+G A    P   
Sbjct: 862 FTDYDIRFYLYELMKALDFCHSMGIMHRDVKPHNVMIDHENKKLRLIDWGLAEFYHPGME 1041

Query: 176 -NSFVGTPYWMAPEVILAMDEGQYDGKVDIWSLGITCIELAERKPPL 221
            N  V + Y+  PE++L  D   YD  +D+WSLG     +  RK PL
Sbjct: 1042YNVRVASRYFKGPELLL--DYQMYDYSLDMWSLGCMFASMIFRKEPL 1176
>28638
          Length = 1458

 Score = 55.1 bits (131), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 29/82 (35%), Positives = 48/82 (58%), Gaps = 3/82 (3%)
 Frame = -1

Query: 143 LIHRDIKAGNILLTEP--GQVKLADFGSAS-MASPANSFVGTPYWMAPEVILAMDEGQYD 199
           +IH D+K  NILL  P    +K+ DFGS+  +      ++ + ++ +PEV+L +    YD
Sbjct: 768 IIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGVP---YD 598

Query: 200 GKVDIWSLGITCIELAERKPPL 221
             +D+WSLG   +E+   +PPL
Sbjct: 597 LAIDMWSLGCILVEMHTGEPPL 532
>26560
          Length = 398

 Score = 53.5 bits (127), Expect = 3e-07,   Method: Composition-based stats.
 Identities = 40/113 (35%), Positives = 58/113 (51%), Gaps = 4/113 (3%)
 Frame = -1

Query: 121 EVEIAAITHGALQGLAYLHFHSLIHRDIKAGNILLTEPGQVKLADFGSA---SMASPANS 177
           E E+       + GL ++H   +++RD+K  NILL E G V+++D G A   S   P  S
Sbjct: 359 EKEVRFYAAEVMLGLEHMHSRFVVYRDLKPANILLDENGHVRISDLGLACDFSKKRPHAS 180

Query: 178 FVGTPYWMAPEVILAMDEGQ-YDGKVDIWSLGITCIELAERKPPLFNMNAMSA 229
            VGT  +MAPEV++   +GQ YD   D +S G    +L +   P    N   A
Sbjct: 179 -VGTHGYMAPEVLM---KGQSYDSSADWFSFGCMLYKLLKGHSPFRQHNQGQA 33
>17253
          Length = 483

 Score = 53.5 bits (127), Expect = 3e-07,   Method: Composition-based stats.
 Identities = 36/135 (26%), Positives = 71/135 (52%), Gaps = 15/135 (11%)
 Frame = -1

Query: 48  EVVAVKKMSYSGKQTHEKWQDILKEVKFLQQL-KHPNTIEYKGCYLKEHTAWLVMEYCLG 106
           + VAVK  +++   T  +  + L+E+  +++L +HPN + + GC      A ++ME+C  
Sbjct: 465 DTVAVK--THNEAATDAEKSEFLRELSIMRKLPRHPNVVSFMGCCTMSDPALILMEFC-- 298

Query: 107 SASDLLEVHKK--PLQEVEIAAITHG------------ALQGLAYLHFHSLIHRDIKAGN 152
              DLL   +K  P + V + +  +               +G+A++  + ++HRD+ A N
Sbjct: 297 CHGDLLSFLRKRRPDRTVFLTSTANDLTARDFFSFALHVARGMAHVANNKIVHRDVAARN 118

Query: 153 ILLTEPGQVKLADFG 167
           +L++E    K++DFG
Sbjct: 117 VLISERNVCKVSDFG 73
>28157
          Length = 400

 Score = 52.8 bits (125), Expect = 6e-07,   Method: Compositional matrix adjust.
 Identities = 42/129 (32%), Positives = 70/129 (54%), Gaps = 8/129 (6%)
 Frame = +3

Query: 50  VAVKKMSYSGKQTHEKWQDILKEVKFLQQLKHPNTIE-YKGCYLKEHTAWLVMEYCLGSA 108
           VAVK++     ++ ++ +  ++E+K L ++ HPN +  Y  C  ++H   LVMEY  G +
Sbjct: 9   VAVKRI-----ESEQEKKSFMQELKQLSRVSHPNIVCLYGAC--RDHPVCLVMEYAEGGS 167

Query: 109 SDLLEVHKKPLQEVEIAAITHGALQ---GLAYLHF---HSLIHRDIKAGNILLTEPG-QV 161
              +     P  +   A   +  LQ   G+ YLH     +LIHRD+K  N+LL + G ++
Sbjct: 168 LYNVLHGSGPQPQYTAAHAMNWLLQCALGVEYLHGMKPKALIHRDLKPPNLLLIQCGTKL 347

Query: 162 KLADFGSAS 170
           K+ DFG+A 
Sbjct: 348 KICDFGTAC 374
>21210
          Length = 518

 Score = 52.4 bits (124), Expect = 8e-07,   Method: Composition-based stats.
 Identities = 38/101 (37%), Positives = 54/101 (53%), Gaps = 4/101 (3%)
 Frame = +3

Query: 182 PYWMAPEVI--LAMDEGQYDGKVDIWSLGITCIELAERKPPLFN-MNAMSALYHIAQNDS 238
           PY MAPE I   A   G YD + D+WSLGIT +ELA  + P    ++    L  + +  +
Sbjct: 15  PY-MAPERIDPRASSHG-YDVRSDVWSLGITLMELATGRFPYRKWVSIFDQLQQVVRGVA 188

Query: 239 PTL-QSREWTDSFRRFVDYCLHKIPQERPAAVELLRHDFIR 278
           P L     ++  F  FV+ CL K  ++RP   +LL H F+R
Sbjct: 189 PCLPHDGAFSHDFVNFVNKCLTKDEKQRPKYNKLLAHPFVR 311
>07836
          Length = 1478

 Score = 52.4 bits (124), Expect = 9e-07,   Method: Compositional matrix adjust.
 Identities = 47/161 (29%), Positives = 78/161 (48%), Gaps = 24/161 (14%)
 Frame = -1

Query: 79   LKHPNTIEYKGCYLKEHTAW----LVMEYC-LGSASDLLEVHKKPLQEVEIAAITHGALQ 133
            L+H N + +    +K   +W    L+ +Y   GS  D L    + L   E+ A+ H A+ 
Sbjct: 1394 LRHENILGFIAADIKGTGSWTQLFLITDYHENGSLHDYL--LSRVLDSSEMLALAHSAIC 1221

Query: 134  GLAYLHFH--------SLIHRDIKAGNILLTEPGQVKLADFGSAS--------MASPANS 177
            GLA+LH          ++ HRDIK+ NIL+ + G   +AD G A         +    N 
Sbjct: 1220 GLAHLHIEIFGTRGKPAIAHRDIKSKNILVKKNGTCCIADLGLAVRYISESNEVDVAPNP 1041

Query: 178  FVGTPYWMAPEVI-LAMDEGQYDG--KVDIWSLGITCIELA 215
              GT  +MAPEV+ + ++   +D   + D+++ G+   E+A
Sbjct: 1040 RQGTKRYMAPEVLEMLLNVKNFDAFKQADMYAFGLVMWEIA 918
>27405
          Length = 532

 Score = 52.0 bits (123), Expect = 1e-06,   Method: Composition-based stats.
 Identities = 34/87 (39%), Positives = 49/87 (56%), Gaps = 4/87 (4%)
 Frame = -3

Query: 121 EVEIAAITHGALQGLAYLHFHSLIHRDIKAGNILLTEPGQVKLADFGSA---SMASPANS 177
           E E+       + GL ++H   +++RD+K  NILL E G V+++D G A   S   P  S
Sbjct: 257 EKEVRFYAAEVMLGLEHMHSRFVVYRDLKPANILLDENGHVRISDLGLACDFSKKKPHAS 78

Query: 178 FVGTPYWMAPEVILAMDEGQ-YDGKVD 203
            VGT  +MAPEV++   +GQ YD   D
Sbjct: 77  -VGTHGYMAPEVLM---KGQAYDSSAD 9
>17975
          Length = 449

 Score = 50.8 bits (120), Expect = 2e-06,   Method: Composition-based stats.
 Identities = 39/140 (27%), Positives = 68/140 (48%), Gaps = 4/140 (2%)
 Frame = +3

Query: 35  FGAVYFATNAHTNEVVAVKKMSYSGKQTHEKWQDILKEVKFLQQLKHPNTIEYKGCYLKE 94
           F  V  A +  T E VAVK +  + K        + +EV+ ++ ++HPN +        +
Sbjct: 6   FAVVKLARHVFTGEKVAVKVIDKT-KLDEVSRSHLFQEVRCMKLVQHPNVVRLYEVIDTQ 182

Query: 95  HTAWLVMEYCLGSASDLLEV---HKKPLQEVEIAAITHGALQGLAYLHFHSLIHRDIKAG 151
              +L++E  LG   D+ +    H   L+E          ++ ++Y H   ++HRD+K  
Sbjct: 183 TKLYLILE--LGDGGDMYDYIMRHSGGLEEKLAKRYFRQIVEAISYCHKLHVVHRDLKPE 356

Query: 152 NILLTE-PGQVKLADFGSAS 170
           N++  E PG VKL DFG ++
Sbjct: 357 NVVFFEKPGLVKLTDFGFST 416
>12672
          Length = 773

 Score = 48.9 bits (115), Expect = 9e-06,   Method: Composition-based stats.
 Identities = 31/98 (31%), Positives = 46/98 (46%), Gaps = 10/98 (10%)
 Frame = +3

Query: 127 ITHGALQGLAYLHFHSLIHRDIKAGNILLTEPGQVKLADF--------GSASMASPANSF 178
           I  G   G+ YL+ +  +HRDIK  NILL      K+ DF        G       A+  
Sbjct: 6   IVKGTASGIQYLNDNGHVHRDIKTANILLDSEYTAKVGDFATVVSAPSGEGKTVQNASVV 185

Query: 179 VGTPYWMAPEVILAMDEGQYD--GKVDIWSLGITCIEL 214
           +GT  ++APE I       +D   K+D +S G+  +E+
Sbjct: 186 IGTAAYLAPEAI------HFDVSTKLDSYSFGVVLLEV 281
>12786
          Length = 460

 Score = 48.9 bits (115), Expect = 9e-06,   Method: Composition-based stats.
 Identities = 42/135 (31%), Positives = 61/135 (45%), Gaps = 23/135 (17%)
 Frame = -3

Query: 132 LQGLAYLHFHSLIHRDIKAGNILLTEPGQVKLADFGSASMASP------ANSFVGTPYWM 185
           L+ +  LH   +IH D+K  N +L   G +KL DFG A+           +S VGTP +M
Sbjct: 380 LRAVKALHNEGVIHSDLKPANFMLV-AGNLKLIDFGIANTLQQDKTSVLKDSRVGTPSYM 204

Query: 186 APEVILAM------DEGQYDG-----------KVDIWSLGITCIELAERKPPLFNMNAMS 228
           +PE I+A       D  + DG           + D+WSLG  CI        L+NM    
Sbjct: 203 SPEAIMAACDDSADDSMEEDGHRTKPKYKVGVRSDVWSLG--CI--------LYNMVYGR 54

Query: 229 ALYHIAQNDSPTLQS 243
             +   +N+   LQ+
Sbjct: 53  TPFQHIKNNMGKLQA 9
>14477
          Length = 493

 Score = 47.8 bits (112), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 47/171 (27%), Positives = 81/171 (47%), Gaps = 3/171 (1%)
 Frame = -1

Query: 21  EELFIDLHEIGHGSFGAVY-FATNAHTNEVVAVKKMSYSGKQTHEKWQDILKEVKFLQQL 79
           E++ +D  ++G G+FG+V          E+    K+  +         +++KE + ++++
Sbjct: 493 EQIQMDELKLGAGNFGSVMKGVCRLDDREIPVAIKVLKNADLDPSVQSELIKEAEVMKKM 314

Query: 80  KHPNTIEYKGCYLKEHTAWLVMEYC-LGSASDLLEVHKK-PLQEVEIAAITHGALQGLAY 137
            H + +   G    E T  LV+E   LG  +  L  +K  PL    I  +     QG+ Y
Sbjct: 313 DHMHIVRLIGLCEGE-TMMLVLELAKLGPLNKFLPKNKHLPLWN--ILELMWQVSQGMEY 143

Query: 138 LHFHSLIHRDIKAGNILLTEPGQVKLADFGSASMASPANSFVGTPYWMAPE 188
           L  +  +HRD+ A NILL +    K++DFG +   S  N+     Y+MA E
Sbjct: 142 LEANKFVHRDLAARNILLCDEHFAKISDFGMSKTLSRENN-----YYMAQE 5
>07940
          Length = 1336

 Score = 47.4 bits (111), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 33/104 (31%), Positives = 52/104 (50%), Gaps = 6/104 (5%)
 Frame = -3

Query: 117 KPLQEVEIAAITHGALQGLAYLHFHSLIHRDIKAGNILLTEPGQVKLADFGSASMASPAN 176
           K L   ++ +  +   +G+ YL     IHRD+ A N+L+ E   +K+ADFG        +
Sbjct: 362 KMLTPKDLISYAYQVARGMEYLASKQCIHRDLAARNVLVAEEYVLKIADFGLTRNLQQFD 183

Query: 177 SFVGT-----PY-WMAPEVILAMDEGQYDGKVDIWSLGITCIEL 214
            +  T     P  WMAPE   A+ + +Y  K D+WS G+   E+
Sbjct: 182 YYRKTTDGRLPVKWMAPE---ALFDRKYTSKSDVWSYGVLLWEI 60
>32691
          Length = 295

 Score = 47.0 bits (110), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 20/50 (40%), Positives = 31/50 (62%)
 Frame = +1

Query: 246 WTDSFRRFVDYCLHKIPQERPAAVELLRHDFIRRERPPKVLIDLIQRTKD 295
           W+  F  FV  CL K P+ R  AV+LL+HDFI++    ++L  +I+  K+
Sbjct: 85  WSTEFIDFVSKCLVKNPENRATAVDLLQHDFIKKAEACEILQAMIREAKE 234
>18996
          Length = 491

 Score = 45.1 bits (105), Expect = 1e-04,   Method: Composition-based stats.
 Identities = 40/150 (26%), Positives = 68/150 (45%), Gaps = 13/150 (8%)
 Frame = +2

Query: 144 IHRDIKAGNILLTEPGQVKLADFGSASMASPANSFVGTPY------WMAPEVILAMDEGQ 197
           IHRD+ A NIL+ +   VK++DFG A  A+    + G         W +PE   A++  +
Sbjct: 2   IHRDLAARNILV-DRSCVKISDFGLAQFANADGYYYGISQRDIPIKWYSPE---AIETCK 169

Query: 198 YDGKVDIWSLGITCIELAERKP-----PLFNMNAMSALYHIAQNDSPTLQSREWTDSF-- 250
           +    D+WS G+T  E+  R       P  ++     L  + + +   L   E    F  
Sbjct: 170 FSSYSDVWSYGVTLFEMFSRGEIPNLLPGHDLTQEEFLNRLRKGER--LPKPELCSDFVY 343

Query: 251 RRFVDYCLHKIPQERPAAVELLRHDFIRRE 280
              +  C H++P+ RP   ++++   I RE
Sbjct: 344 SELMRPCWHEMPKSRPTFHQIIQ--IIARE 427
>06358
          Length = 1517

 Score = 45.1 bits (105), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 59/233 (25%), Positives = 99/233 (42%), Gaps = 37/233 (15%)
 Frame = +3

Query: 31  GHGSFGAVYFATNAHTNEVVAV-----KKMSYSGKQTHEKWQDILK-EVKFLQQLKHPNT 84
           G G    V+ A+   T E  +V     K +    ++  E   ++L+  V+ L +L+HP  
Sbjct: 33  GPGLLWKVFAASKKSTKEEASVFVFEKKSVDRYSRRDREAIVEVLRVGVQQLTKLRHPKI 212

Query: 85  IEY--------KGCYLKEHTAWLVMEYCLGSASDLLEVHKKPLQEVEI--AAITHGALQ- 133
           +          +         +  +   LG  S +  V K+ LQ+ ++    I HG LQ 
Sbjct: 213 LAVINPLEESRETLAFATEPVFASLANVLGDLSSIXTVPKE-LQDYQLYDVEIKHGLLQV 389

Query: 134 --GLAYLHFHS-LIHRDIKAGNILLTEPGQVKLADFGSASMAS------PANSF------ 178
              L +LH  + ++HR++    I+LT+ G  KLA +     +S      P+  F      
Sbjct: 390 TEALGFLHNDAKMMHRNVCPEAIMLTKLGSWKLAGYEFCVRSSDPQSTDPSYPFYEWRSD 569

Query: 179 ---VGTPY--WMAPEVILAMDEGQYDGKVDIWSLGITCIELAERKPPLFNMNA 226
              V  P+  +MAPE +L M  G      D++SLG+    +  +  PLF  N 
Sbjct: 570 IAPVTQPHLDFMAPEYVLTMQCGTGS---DMFSLGLLVYSVFAKGKPLFECNG 719
>17516
          Length = 453

 Score = 44.3 bits (103), Expect = 2e-04,   Method: Composition-based stats.
 Identities = 21/40 (52%), Positives = 27/40 (67%)
 Frame = -3

Query: 175 ANSFVGTPYWMAPEVILAMDEGQYDGKVDIWSLGITCIEL 214
           A +  GTP +MAPEV+L   +GQYD K D++SL I   EL
Sbjct: 448 AGTLAGTPVYMAPEVLL--QKGQYDMKADVYSLAIILWEL 335
>25019
          Length = 730

 Score = 43.9 bits (102), Expect = 3e-04,   Method: Composition-based stats.
 Identities = 27/72 (37%), Positives = 38/72 (52%), Gaps = 4/72 (5%)
 Frame = +3

Query: 150 AGNILLTEPGQVKLADFGSASMA----SPANSFVGTPYWMAPEVILAMDEGQYDGKVDIW 205
           A N+LL + G VKL DFG    A       ++F GT  +MAPE++     G+    VD W
Sbjct: 258 AENVLLDKDGHVKLTDFGLCKEAITGTRVTHTFCGTIEYMAPEILTRTGHGK---AVDWW 428

Query: 206 SLGITCIELAER 217
           SLG + +   +R
Sbjct: 429 SLGSSYV*YVDR 464
>02638
          Length = 1490

 Score = 43.5 bits (101), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 30/106 (28%), Positives = 51/106 (48%), Gaps = 4/106 (3%)
 Frame = +1

Query: 178 FVGTPYWMAPEVILAMDEGQYDGK-VDIWSLGITCIELAERKPPLFN---MNAMSALYHI 233
            +GT  +MAPEV+     G+  G+  D+WS+G   IE+   +PP  +    N ++ ++ I
Sbjct: 16  LLGTIAFMAPEVL----RGESYGRACDVWSVGCVMIEMCTCRPPWNSHDISNHLALIFKI 183

Query: 234 AQNDSPTLQSREWTDSFRRFVDYCLHKIPQERPAAVELLRHDFIRR 279
           A +  P       +   R  +  CL +    RP+A +LL H    +
Sbjct: 184 ASSVDPPPIPENMSPPVRDLMLRCLEQDSDFRPSAKDLLMHPLFTK 321
>32359
          Length = 928

 Score = 42.4 bits (98), Expect = 8e-04,   Method: Compositional matrix adjust.
 Identities = 37/137 (27%), Positives = 70/137 (51%), Gaps = 10/137 (7%)
 Frame = -1

Query: 18  DDPEEL-FIDLHEIGHGSFGAVYFATNAHTNEVVAVKKMSYSGKQTHEKWQDILKEVKFL 76
           D P+E+ + D   IG+GSFG VY A    T+E+VA+KK+        +++++  +E++ +
Sbjct: 445 DRPQEVSYTDAKVIGNGSFGVVYQAKLVDTSELVAIKKV-----LQDKRFKN--RELQIM 287

Query: 77  QQLKHPNTIEYKGCYLK------EHTAWLVMEYCLGSASDLLEVHKKPLQEVEIAAI--- 127
           ++L+H N ++ K  +        E    LV+EY   +   +   + K  Q + I  I   
Sbjct: 286 RKLEHQNIVKLKFFFYSSGEKKDEVFLNLVLEYVPETVYRVARHYSKSKQTIPILYIKLY 107

Query: 128 THGALQGLAYLHFHSLI 144
            +   + LAY+H  + +
Sbjct: 106 MYQLFRSLAYIHSQACV 56
>13840
          Length = 446

 Score = 40.8 bits (94), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 35/128 (27%), Positives = 59/128 (46%), Gaps = 5/128 (3%)
 Frame = -1

Query: 26  DLHEIGHGSFGAVYFATNAHTNEVVAVKKMSYSGKQTHEKWQDILKEVKFLQQLKHPNTI 85
           D+ EIG G++G V    +  T+ V+AVK++  S  +  E+ Q ++     ++    P  +
Sbjct: 383 DMGEIGRGNYGTVNKMRHKITSTVMAVKRIR-STVEEREQKQLLMDLDVVMRSNNCPFIV 207

Query: 86  EYKGCYLKEHTAWLVMEYCLGSASDLLEVHKKPLQ----EVEIAAITHGALQGLAYLHFH 141
           ++ G   KE   W+ ME    S     +     +Q    E  +  IT   L+ L YL   
Sbjct: 206 QFYGALFKEGDCWICMELMETSLDKFYKFVYGEMQSSIPENILGKITVATLKALNYLKEE 27

Query: 142 -SLIHRDI 148
             +IHRD+
Sbjct: 26  LRIIHRDV 3
>20640
          Length = 1492

 Score = 40.0 bits (92), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 30/131 (22%), Positives = 53/131 (40%), Gaps = 7/131 (5%)
 Frame = +1

Query: 144 IHRDIKAGNILLTEPGQVKLADFGSASMASPANSFVGTPY------WMAPEVILAMDEGQ 197
           +HRD+   N L+     VK++DFG A      + + G+ +      WM  E IL     +
Sbjct: 10  VHRDLATRNCLVGHDLVVKISDFGLARSVHSVDYYRGSEHDAIPIRWMPLEAILY---NK 180

Query: 198 YDGKVDIWSLGITCIEL-AERKPPLFNMNAMSALYHIAQNDSPTLQSREWTDSFRRFVDY 256
           +  + D+WS G+   E+ A    P + +     +  + +        R         +  
Sbjct: 181 FSTQSDVWSFGVVLWEIFAFALQPYYGLTHEEVVRFVKEGKVLACPERT-PPPMYELMKQ 357

Query: 257 CLHKIPQERPA 267
           C H+ P  RP+
Sbjct: 358 CWHRRPATRPS 390
>17300
          Length = 480

 Score = 38.5 bits (88), Expect = 0.011,   Method: Composition-based stats.
 Identities = 28/89 (31%), Positives = 39/89 (43%), Gaps = 8/89 (8%)
 Frame = +1

Query: 134 GLAYLHFHSLIHRDIKAGNILLTEPGQVKLADFG-SASMASPANSFVGTP-------YWM 185
           G+  L     +HRD+ A NIL+ E    K+ADFG S  + S       T         W 
Sbjct: 10  GMGXLADMGYVHRDLAARNILVNEILVCKVADFGLSREIESDTTEGAYTTKGGKIPVRWT 189

Query: 186 APEVILAMDEGQYDGKVDIWSLGITCIEL 214
           APE I      ++    D+WS G+   E+
Sbjct: 190 APEAIAYR---KFTSASDVWSFGVVMWEV 267
>32000
          Length = 644

 Score = 38.5 bits (88), Expect = 0.012,   Method: Composition-based stats.
 Identities = 26/79 (32%), Positives = 41/79 (51%), Gaps = 4/79 (5%)
 Frame = -1

Query: 159 GQVKLADFGSASM-ASPANSF---VGTPYWMAPEVILAMDEGQYDGKVDIWSLGITCIEL 214
            ++K+ADFG A +   P  ++   V T ++ APE++L      Y   VDIWSLG   +E+
Sbjct: 578 AKMKIADFGLARVFGLPVRTYTHEVITLWYRAPEILLGCR--FYSVPVDIWSLGCIFVEM 405

Query: 215 AERKPPLFNMNAMSALYHI 233
             R+      + +  LY I
Sbjct: 404 MTRRALFPGDSEIDQLYRI 348
>18663
          Length = 600

 Score = 36.2 bits (82), Expect = 0.059,   Method: Composition-based stats.
 Identities = 19/45 (42%), Positives = 27/45 (60%), Gaps = 1/45 (2%)
 Frame = +2

Query: 176 NSFVGTPYWMAPEVILAMDEGQYDGKVDIWSLGITCIE-LAERKP 219
           ++F GTP ++APE++   D   Y   VD W+LG+   E LA R P
Sbjct: 2   STFCGTPNYIAPEILRGED---YGFSVDWWALGVLLYEMLAGRSP 127
>11185
          Length = 473

 Score = 36.2 bits (82), Expect = 0.059,   Method: Composition-based stats.
 Identities = 34/140 (24%), Positives = 51/140 (36%), Gaps = 33/140 (23%)
 Frame = +1

Query: 132 LQGLAYLHFHSLIHRDIKAGNILLTEPGQVKLADFG------------------------ 167
           + GL Y+H   ++  D++   +LL   G +K ADFG                        
Sbjct: 31  VTGLHYIHSLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEAGDQWN 210

Query: 168 --SASMASPANSFVGTPYWMAPEVILAMDEGQYDGKVDIWSLGITCIEL-------AERK 218
             SA          G+P +MAPEV    +        D+W+LG    E+       A+  
Sbjct: 211 IQSAEEMMKQVPTSGSPTYMAPEVFQGAEPSIMS---DLWALGCVFYEMFSGSRLSAKPS 381

Query: 219 PPLFNMNAMSALYHIAQNDS 238
           P   N+     L  + Q DS
Sbjct: 382 PEFLNL-----LESLLQKDS 426
>00486
          Length = 797

 Score = 36.2 bits (82), Expect = 0.066,   Method: Composition-based stats.
 Identities = 28/93 (30%), Positives = 40/93 (43%), Gaps = 3/93 (3%)
 Frame = -2

Query: 176 NSFVGTPYWMAPEVILAMDEGQYDGKVDIWSLGITCIELAERKPPLFNMNAMSALYHIAQ 235
           ++F GT  +MAPE++     G+    VD WSLG    ++    PP    N    +  I +
Sbjct: 784 HTFCGTIEYMAPEILTRTGHGK---AVDWWSLGALMYDMLTGSPPFTAENRKKTIDKILK 614

Query: 236 ---NDSPTLQSREWTDSFRRFVDYCLHKIPQER 265
              N  P L     T+  R  +   L K P ER
Sbjct: 613 GKLNLPPYL-----TNEARGLIKKLLRKNPAER 530
>07833
          Length = 1504

 Score = 35.8 bits (81), Expect = 0.082,   Method: Compositional matrix adjust.
 Identities = 47/211 (22%), Positives = 81/211 (38%), Gaps = 11/211 (5%)
 Frame = -3

Query: 67   QDILKEVKFLQQLKHPNTIEYKGCYLKEHTAWLVMEYC-LGSASDLLEVHKKPL----QE 121
            +D ++E   L+   HPN +    C  +     L+ ++   GS  + L      +    Q 
Sbjct: 1484 RDFMEEFPRLRIFNHPNVLPVLACCNQPPNLVLISQFMPFGSLYNTLHGESGIVVDQNQS 1305

Query: 122  VEIAAITHGALQGLAYLHFHSLIHRDIKAGNILLTEPGQVKLADFGS-ASMASPANSF-- 178
            +  A       +G+ +LH       +    N LLT    +   D  +  +MA    SF  
Sbjct: 1304 LRFAM---DIARGMEFLH-----SMEPTIPNFLLTSKHVMIDEDLTARINMADYCFSFHE 1149

Query: 179  ---VGTPYWMAPEVILAMDEGQYDGKVDIWSLGITCIELAERKPPLFNMNAMSALYHIAQ 235
               V +P WMAPE +    +       D+WS  I   EL  R+ P   +++M     +A 
Sbjct: 1148 KGKVYSPAWMAPEALQRRPDDINTRAADMWSFAILMWELETREVPFAELSSMEVGMKVAL 969

Query: 236  NDSPTLQSREWTDSFRRFVDYCLHKIPQERP 266
                       +    R +  C+++ P +RP
Sbjct: 968  EGLRISIPPGISLHMSRLIKICMNEEPGKRP 876
>31489
          Length = 329

 Score = 35.8 bits (81), Expect = 0.085,   Method: Compositional matrix adjust.
 Identities = 30/93 (32%), Positives = 45/93 (48%), Gaps = 11/93 (11%)
 Frame = +3

Query: 73  VKFLQQLKHPNTIEY------KGCY--LKE-HTAWLVMEYCLGSASDLLEV--HKKPLQE 121
           +K L+  KH N I        K  Y   K+ H  + +ME      SDL  +    +PL E
Sbjct: 3   IKILKHFKHDNIISIREILKPKDSYHDFKDIHVVFDLME------SDLHRIIYSDQPLTE 164

Query: 122 VEIAAITHGALQGLAYLHFHSLIHRDIKAGNIL 154
             I    +  L+GL Y+H  +++HRD+K  N+L
Sbjct: 165 EHIRYFLYQILRGLKYIHSANVVHRDLKPSNLL 263
>16708
          Length = 1397

 Score = 34.3 bits (77), Expect = 0.20,   Method: Compositional matrix adjust.
 Identities = 46/163 (28%), Positives = 70/163 (42%), Gaps = 18/163 (11%)
 Frame = -1

Query: 27   LHEIGHGSFGAVYFATNAHTNEVVAVKKMSYSGKQTHEKWQDILKEVKFLQQLKHPNTIE 86
            L  +G G FG VY A    T+E  A+K    +    H      L EV+ L +++      
Sbjct: 1388 LQVLGKGVFGKVYEARLLSTHEKAALK----TSILCHHS----LDEVEALGRIE------ 1251

Query: 87   YKGCYLKE-HTAW-----------LVMEYCLGSASDLLEVHKK---PLQEVEIAAITHGA 131
              G YL +   AW           L+  Y +G   ++   +K    P++    A +   A
Sbjct: 1250 -GGFYLAQMFGAWVTCLPFPKMNILLHFYEMGPLCNVYAHYKNKEMPIRWSNPAMVCCIA 1074

Query: 132  LQGLAYL-HFHSL--IHRDIKAGNILLTEPGQVKLADFGSASM 171
             Q +  L H H L  +H D+KA N+L+   G  KL D+G A +
Sbjct: 1073 GQXVCALEHIHELGVVHMDVKADNVLVDAHGNCKLTDYGIAQL 945
>37063
          Length = 455

 Score = 34.3 bits (77), Expect = 0.21,   Method: Composition-based stats.
 Identities = 26/76 (34%), Positives = 37/76 (48%), Gaps = 14/76 (18%)
 Frame = -2

Query: 148 IKAGNIL---LTEPGQVKLADF---------GSASMASPANSFVGTPYWMAPEVILAM-- 193
           +K  NIL   L E   +K+ DF         G  +      + VG+  +MAPEV+ A   
Sbjct: 454 LKPENILCEHLDEVVPLKICDFDLASGINCDGDGTKTPELLTPVGSAEYMAPEVVDAWVG 275

Query: 194 DEGQYDGKVDIWSLGI 209
           +   YD + D+WSLGI
Sbjct: 274 ESFSYDKRCDMWSLGI 227
>08294
          Length = 1849

 Score = 33.5 bits (75), Expect = 0.43,   Method: Compositional matrix adjust.
 Identities = 46/214 (21%), Positives = 82/214 (38%), Gaps = 24/214 (11%)
 Frame = +2

Query: 82   PNTIEYKGCYLKEHTAWLVMEYC-------------------LGSASDLLEVHKKPLQEV 122
            PN + + G   +    +L+ EYC                    G+    L + +K     
Sbjct: 887  PNIVHFMGVCREAEPHFLITEYCDWGDLKQFLLATRNDNGRGRGTRVPALALSQKLGMGQ 1066

Query: 123  EIAAITHGALQGLAYLHFHSLIHRDIKAGNILLTEPGQVKLADFG-----SASMASPANS 177
            ++AA       G+  L    L+H D+ A N+LLT   Q+K+A         AS   P + 
Sbjct: 1067 QVAA-------GMEALSNQGLVHGDLAARNVLLTSRMQLKVARPALSGDVYASEYYPLHQ 1225

Query: 178  FVGTPYWMAPEVILAMDEGQYDGKVDIWSLGITCIELAERKPPLFNMNAMSALYHIAQND 237
             +    W+ PE +L  D     G  D+W+ G+   E+ +     + + +   +    Q+ 
Sbjct: 1226 RLVPLRWLPPEGVLE-DSATTCG--DVWAFGVFLWEVLQLADLPYRLMSDEEVLRSLQHS 1396

Query: 238  SPTLQSREWTDSFRRFVDYCLHKIPQERPAAVEL 271
               L S +   +    +  C  + P +RP   E+
Sbjct: 1397 QAALDSPDAPPALLSLLQRCTAQQPSQRPPFSEI 1498
>31789
          Length = 676

 Score = 32.7 bits (73), Expect = 0.59,   Method: Compositional matrix adjust.
 Identities = 28/97 (28%), Positives = 43/97 (44%), Gaps = 6/97 (6%)
 Frame = +2

Query: 5   ALKDPEIADLFFKDDPEELFIDLH-EIGHGSFGAVYFATNAHTNEVVAVKKMSYSGKQTH 63
           A K  EI +      P+  F+    EIG GSF  VY   +      VA  ++        
Sbjct: 266 AQKVQEIEEKAVASSPDNRFLKFDVEIGRGSFKTVYKGLDTELGVAVAWCELQ------D 427

Query: 64  EKW-----QDILKEVKFLQQLKHPNTIEYKGCYLKEH 95
           +KW     Q   +E + L++L+HPN + +   Y +EH
Sbjct: 428 KKWNKTERQRFKEEAEMLKELQHPNIVRFFD-YWEEH 535
>11516
          Length = 1175

 Score = 32.7 bits (73), Expect = 0.63,   Method: Compositional matrix adjust.
 Identities = 34/120 (28%), Positives = 52/120 (43%), Gaps = 7/120 (5%)
 Frame = +3

Query: 63  HEKWQDILKEVKFLQQLKHPNTIEYKG-C-----YLKEHTAWLVMEYCLGSASDLLE-VH 115
           H   Q I+KE+  LQ L H N ++  G C     Y  E    +VM   LG   DL++ +H
Sbjct: 660 HRAAQKIVKEIVLLQALAHDNVVQVLGFCVPDKAYDGEGDTTVVMVTELGEPIDLIKLLH 839

Query: 116 KKPLQEVEIAAITHGALQGLAYLHFHSLIHRDIKAGNILLTEPGQVKLADFGSASMASPA 175
                 + I+      L  L+     +L+  D +    +L + G +KL+D   A    PA
Sbjct: 840 MSWEDRLRISYDLTKLLHFLSQSARGALVMNDFRRQQFVLVD-GALKLSDVDDAGFDEPA 1016
>00394
          Length = 548

 Score = 32.0 bits (71), Expect = 1.0,   Method: Compositional matrix adjust.
 Identities = 23/78 (29%), Positives = 37/78 (47%), Gaps = 1/78 (1%)
 Frame = -2

Query: 20  PEELFIDL-HEIGHGSFGAVYFATNAHTNEVVAVKKMSYSGKQTHEKWQDILKEVKFLQQ 78
           P+  F+    EIG GSF  VY   +      VA  ++        E+ Q   +E + L++
Sbjct: 307 PDNRFLKFDKEIGRGSFKTVYKGLDTELGVAVAWCELQDKKWNKAER-QRFKEEAEMLKE 131

Query: 79  LKHPNTIEYKGCYLKEHT 96
           L+HPN + +   Y +EH 
Sbjct: 130 LQHPNIVRFFD-YWEEHN 80
>18481
          Length = 437

 Score = 32.0 bits (71), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 31/118 (26%), Positives = 52/118 (44%), Gaps = 6/118 (5%)
 Frame = -1

Query: 72  EVKFLQQL-KHPN--TIEYKGCYLKEHTAWLVMEYCLGSASDLLEVHKKPLQEVEIAAIT 128
           E K  +Q+ +HP   T+ + G   ++H   LVME    S  +L  + K+      I  ++
Sbjct: 350 EAKVYEQIGRHPGLPTMYHYGT--EKHFNALVMELLGPSLEELFVICKRRFTLKTILMVS 177

Query: 129 HGALQGLAYLHFHSLIHRDIKAGNILLT---EPGQVKLADFGSASMASPANSFVGTPY 183
              L  L ++H    IHRD+K  N L+       ++ + DFG +         +  PY
Sbjct: 176 DQLLSRLEFIHQKCFIHRDLKPDNFLMGLGRHCHRLYIIDFGLSKRYKDTQGTMHIPY 3
>11404
          Length = 563

 Score = 32.0 bits (71), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 48/153 (31%), Positives = 64/153 (41%), Gaps = 15/153 (9%)
 Frame = +1

Query: 20  PEELFIDLHEI----GHGSFGAVYFATNAHTNEVVAVKKMSYSGKQTHEKWQDILKEVKF 75
           P E + D +EI    G GSFG V  A +   NE VA+K +    K+       I  EVK 
Sbjct: 121 PGEKWADRYEIDSLIGKGSFGQVVKAYDHTDNEQVAIKIIK--NKKPFLNQAQI--EVKL 288

Query: 76  LQQL-KHPNTIEYKGCYLKEHTAW-----LVMEYCLGSASDLLEVHKKPLQEVEIAAITH 129
           L+ + +H    +Y    LK H  +     LV E    +  DLL       + V +     
Sbjct: 289 LEMMNRHDTDNKYYIVRLKRHFMFRSHLCLVFELLSYNLYDLLR--NTNFRGVSLNLTRK 462

Query: 130 GALQGLAYLHF-----HSLIHRDIKAGNILLTE 157
            A Q    L F      S+IH D+K  NILL  
Sbjct: 463 FAQQLCTALLFLATPEMSIIHCDLKPENILLCN 561
>29360
          Length = 363

 Score = 31.6 bits (70), Expect = 1.7,   Method: Compositional matrix adjust.
 Identities = 35/117 (29%), Positives = 54/117 (46%), Gaps = 6/117 (5%)
 Frame = +3

Query: 46  TNEVVAVKKMSYSGKQTHEKWQDILKEVKFLQQLKHPNTIEYKG-----CYLKEHTAWLV 100
           T+E+VA+K +      ++ +   I  EV  LQ+L   +  +Y       C+  ++   LV
Sbjct: 24  TSEIVAIKILK--NHPSYARQGQI--EVSILQRLSQESADDYNFVRAFECFQHKNHTCLV 191

Query: 101 MEYCLGSASDLLEVHK-KPLQEVEIAAITHGALQGLAYLHFHSLIHRDIKAGNILLT 156
            E    +  D L+ +K +PL    I  IT   L  L  L    LIH D+K  NI+L 
Sbjct: 192 FEMLEQNLYDFLKQNKFQPLPLKYIRPITQQVLTALRKLKQLGLIHADLKPENIMLV 362
>26009
          Length = 886

 Score = 31.2 bits (69), Expect = 1.9,   Method: Composition-based stats.
 Identities = 15/51 (29%), Positives = 29/51 (56%)
 Frame = +3

Query: 123 EIAAITHGALQGLAYLHFHSLIHRDIKAGNILLTEPGQVKLADFGSASMAS 173
           E  ++    +  L ++H   L+HRDIK  N+L+  P   +++ + SA +A+
Sbjct: 714 EAKSVMKQLVSALDFMHSKQLVHRDIKPENVLILTPDFSRVS*WTSA*LAN 866
>32957
          Length = 645

 Score = 31.2 bits (69), Expect = 2.0,   Method: Composition-based stats.
 Identities = 17/38 (44%), Positives = 22/38 (57%)
 Frame = +3

Query: 177 SFVGTPYWMAPEVILAMDEGQYDGKVDIWSLGITCIEL 214
           +F GT  +MAPEV    +  +Y  +VD W LGI   EL
Sbjct: 42  TFCGTREYMAPEV---HERKEYGKEVDWWGLGILLHEL 146
>29011
          Length = 374

 Score = 30.8 bits (68), Expect = 2.2,   Method: Composition-based stats.
 Identities = 19/51 (37%), Positives = 28/51 (54%)
 Frame = +2

Query: 250 FRRFVDYCLHKIPQERPAAVELLRHDFIRRERPPKVLIDLIQRTKDAVREL 300
           F+ F+D CL    + R +AV+LL H F+ +    + L  LI+  K   REL
Sbjct: 92  FKTFLDKCLQVEVESRSSAVDLLTHPFLTKALELRTLGPLIRAAK---REL 235
>30599
          Length = 730

 Score = 30.4 bits (67), Expect = 3.7,   Method: Composition-based stats.
 Identities = 16/51 (31%), Positives = 30/51 (58%), Gaps = 2/51 (3%)
 Frame = -2

Query: 50  VAVKKMSYSGKQTHEKWQDILKEVKFLQ-QLKHPNTIE-YKGCYLKEHTAW 98
           +A+ ++SYSGK  +  + +  +E+  +  +L HP T+E Y G   + +T W
Sbjct: 477 IALYQLSYSGKSFYANYGNFFEELNLVTLRLDHPLTMEPYNG---RNNTTW 334
>09201
          Length = 754

 Score = 29.3 bits (64), Expect = 7.6,   Method: Compositional matrix adjust.
 Identities = 14/32 (43%), Positives = 19/32 (59%)
 Frame = -1

Query: 469 RQHQKQLIALENKLKAEMDEHRLKLQKEVETH 500
           +QH + +  LENK K+EMD  R    + VE H
Sbjct: 532 KQHDRDMAELENKYKSEMDSVRRARDEAVEQH 437
>21800
          Length = 855

 Score = 28.9 bits (63), Expect = 9.3,   Method: Composition-based stats.
 Identities = 17/39 (43%), Positives = 24/39 (61%), Gaps = 1/39 (2%)
 Frame = +2

Query: 118 PLQEVEIAAITHGALQGLAYLHFH-SLIHRDIKAGNILL 155
           P+  V++  I    L+GL YLH   ++IH DIK  NIL+
Sbjct: 626 PVHNVKL--IIRQVLEGLNYLHAKCNIIHTDIKPENILI 736
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|94391740|ref|XP_001001182.1| PREDICTED: similar to
Serine/threonine-protein kinase TAO1 (Thousand and one amino acid
protein 1) [Mus musculus]
         (1001 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

18921                                                                 176   4e-44
13212                                                                 168   1e-41
12721                                                                 160   3e-39
19094                                                                 120   4e-37
00300                                                                 140   2e-33
14420                                                                 132   7e-31
13592                                                                 125   6e-29
01707                                                                 105   1e-22
06405                                                                 100   2e-21
01756                                                                  98   2e-20
01060                                                                  95   1e-19
01718                                                                  95   1e-19
14126                                                                  94   4e-19
29581                                                                  86   3e-17
04591                                                                  86   9e-17
00392                                                                  81   2e-15
37602                                                                  78   4e-15
19301                                                                  78   1e-14
00715                                                                  76   7e-14
03240                                                                  74   3e-13
09606                                                                  74   3e-13
30755                                                                  73   6e-13
04852                                                                  70   5e-12
21808                                                                  70   6e-12
15910                                                                  68   2e-11
18484                                                                  68   2e-11
31885                                                                  66   7e-11
19761                                                                  66   8e-11
14116                                                                  65   9e-11
09007                                                                  65   2e-10
11780                                                                  64   2e-10
01966                                                                  59   3e-10
01392                                                                  62   1e-09
27546                                                                  62   2e-09
21079                                                                  61   2e-09
26560                                                                  61   3e-09
07291                                                                  60   3e-09
13066                                                                  59   1e-08
03508                                                                  58   2e-08
04138                                                                  58   2e-08
21210                                                                  57   3e-08
17975                                                                  57   5e-08
28157                                                                  57   5e-08
21433                                                                  55   1e-07
28638                                                                  55   1e-07
27405                                                                  55   1e-07
12786                                                                  53   6e-07
07940                                                                  52   1e-06
17253                                                                  52   2e-06
12672                                                                  50   3e-06
14477                                                                  50   3e-06
18996                                                                  50   6e-06
02638                                                                  49   7e-06
07836                                                                  49   8e-06
32359                                                                  49   1e-05
06358                                                                  47   3e-05
17516                                                                  44   3e-04
25019                                                                  44   3e-04
16708                                                                  44   5e-04
11185                                                                  42   0.001
17300                                                                  40   0.005
32691                                                                  40   0.005
20640                                                                  38   0.018
32000                                                                  38   0.020
31489                                                                  37   0.040
07833                                                                  36   0.076
18663                                                                  36   0.083
29360                                                                  35   0.13 
00486                                                                  35   0.13 
08294                                                                  35   0.15 
37063                                                                  34   0.26 
18481                                                                  33   0.44 
31789                                                                  33   0.53 
22005                                                                  33   0.69 
20152                                                                  33   0.85 
30360                                                                  32   1.4  
26009                                                                  32   1.4  
00394                                                                  31   1.9  
36481                                                                  31   2.0  
32957                                                                  31   2.7  
11516                                                                  30   3.3  
29011                                                                  29   9.5  
07687                                                                  29   9.5  
>18921
          Length = 697

 Score =  176 bits (446), Expect = 4e-44,   Method: Composition-based stats.
 Identities = 95/213 (44%), Positives = 128/213 (60%), Gaps = 5/213 (2%)
 Frame = +2

Query: 24  PEKLFTDLREIGHGSFGAVYFARDVRTNEVVAIKKMSYSGKQSTEKWQDIIKEVKFLQRI 83
           PE +F  L ++G GS+G+V+ +    T +V+AIK++           Q+IIKE+  +Q+ 
Sbjct: 23  PEDVFDILGKLGEGSYGSVFKSLHKETGQVLAIKQVPVD-----TDLQEIIKEISIMQQC 187

Query: 84  KHPNSIEYKGCYLREHTAWLVMEYC-LGSASDLLEVHKKPLQEVEIAAITHGALQGLAYL 142
                ++Y G Y +    W+VMEYC  GS SD++ +  K L E EIA I +  L+GL YL
Sbjct: 188 DSKYIVKYYGSYFKNTDLWIVMEYCGAGSVSDIMRLRNKTLVEREIATILYYTLKGLXYL 367

Query: 143 HSHTMIHRDIKAGNILLTEPGQVKLADFGSASMASPA----NSFVGTPYWMAPEVILAMD 198
           HS   IHRDIKAGNILL   G  KLADFG A   +      N+ +GTPYWMAPEVI    
Sbjct: 368 HSRRKIHRDIKAGNILLNNEGHAKLADFGVAGQLTDTMAKRNTVIGTPYWMAPEVI---Q 538

Query: 199 EGQYDGKVDVWSLGITCIELAERKPPLFNMNAM 231
           E  YD   D+WSLGIT +E+AE KPP+   + +
Sbjct: 539 EIGYDCVADIWSLGITALEMAEGKPPVMETSIL 637
>13212
          Length = 1067

 Score =  168 bits (425), Expect = 1e-41,   Method: Compositional matrix adjust.
 Identities = 85/203 (41%), Positives = 125/203 (61%), Gaps = 9/203 (4%)
 Frame = -1

Query: 110  GSASDLLEVHKKPLQEVEIAAITHGALQGLAYLHSHTMIHRDIKAGNILLTEPGQVKLAD 169
            G+   ++   +KP+ E +I  + H     L +LH H +IHRDIKAGN+LLT  G+VKLAD
Sbjct: 1028 GALDSIMVDLEKPMTEAQICYVCHEMCMALDFLHRHHVIHRDIKAGNVLLTIDGEVKLAD 849

Query: 170  FGSASMASPA----NSFVGTPYWMAPEVILA--MDEGQYDGKVDVWSLGITCIELAERKP 223
            FG ++  +      ++F+GTPYWMAPEV+L   + +  YD K D+WSLG+T IE A+ +P
Sbjct: 848  FGVSAKNTQTQQKRDTFIGTPYWMAPEVVLCETLKDTPYDFKADIWSLGVTLIEFAQIEP 669

Query: 224  PLFNMNAMSALYHIAQNESPTLQ-SNEWSDYFRNFVDSCLQKIPQDRPTSEELLKHMFVL 282
            P   M+ M  L  I +++ PTL+   +W+  F++F+  CL K P  RPT+ ELL+H F+ 
Sbjct: 668  PNKEMHPMRVLIKIHKSDPPTLEKPKKWTKLFKDFIAKCLVKDPNLRPTAAELLEHPFMK 489

Query: 283  RERP--ETVLIDLIQRTKDAVRE 303
            R     +  + DLI  +K  V E
Sbjct: 488  RATATDKAAICDLIMESKAEVVE 420
>12721
          Length = 821

 Score =  160 bits (404), Expect = 3e-39,   Method: Compositional matrix adjust.
 Identities = 94/256 (36%), Positives = 140/256 (54%), Gaps = 6/256 (2%)
 Frame = +1

Query: 23  DPEKLFTDLREIGHGSFGAVYFARDVRTNEVVAIKKMSYSGKQSTEKWQDIIKEVKFLQR 82
           DP     D  +IG GS G V  A   R    +A+KKM    +Q  E    +  EV  ++ 
Sbjct: 79  DPRTFLDDFMKIGEGSTGIVCIATS-RDGRQMAVKKMDLRKQQRREL---LFNEVVVMRD 246

Query: 83  IKHPNSIEYKGCYLREHTAWLVMEYCLGSA-SDLLEVHKKPLQEVEIAAITHGALQGLAY 141
             HPN +E    YL     W+VME+  G A +D++  ++  + EV+IA +    L+ LA+
Sbjct: 247 YHHPNIVEMYNSYLVNDELWVVMEFMEGGALTDIVTNNR--MDEVQIATVCRACLKALAF 420

Query: 142 LHSHTMIHRDIKAGNILLTEPGQVKLADFGSASMAS----PANSFVGTPYWMAPEVILAM 197
           LH++ +IHRDIK+ +ILL+  G+VKL DFG  +  +       S VGTPYWMAPEVI  +
Sbjct: 421 LHANGVIHRDIKSDSILLSHDGKVKLXDFGFCAQVTQDLQKRKSLVGTPYWMAPEVISRL 600

Query: 198 DEGQYDGKVDVWSLGITCIELAERKPPLFNMNAMSALYHIAQNESPTLQ-SNEWSDYFRN 256
               Y  +VD+WSLGI  +E+ + +PP FN   + A+  I     P L+ +++ S   + 
Sbjct: 601 ---PYGPEVDIWSLGIMVMEMIDAEPPFFNEPPLQAMRRIRDMPPPKLRNTHKISPRLQG 771

Query: 257 FVDSCLQKIPQDRPTS 272
           F+D  L + P  R T+
Sbjct: 772 FIDRMLVRDPHQRATA 819
>19094
          Length = 898

 Score =  120 bits (301), Expect(2) = 4e-37,   Method: Composition-based stats.
 Identities = 63/115 (54%), Positives = 74/115 (64%), Gaps = 4/115 (3%)
 Frame = +1

Query: 110 GSASDLLEVHKKPLQEVEIAAITHGALQGLAYLHSHTMIHRDIKAGNILLTEPGQVKLAD 169
           GS SD++ +  K L E EIA I +  L+GL YLHS   IHRDIKAGNILL   G  KLAD
Sbjct: 10  GSVSDIMRLRNKTLVEREIATILYYTLKGL*YLHSRRKIHRDIKAGNILLNNEGHAKLAD 189

Query: 170 FGSASMASPA----NSFVGTPYWMAPEVILAMDEGQYDGKVDVWSLGITCIELAE 220
           FG A   +      N+ +GTPYWMAPEVI    E  YD   D+WSLGIT +E+AE
Sbjct: 190 FGVAGQLTDTMAKRNTVIGTPYWMAPEVI---QEIGYDCVADIWSLGITALEMAE 345

 Score = 53.9 bits (128), Expect(2) = 4e-37,   Method: Compositional matrix adjust.
 Identities = 26/79 (32%), Positives = 46/79 (58%), Gaps = 1/79 (1%)
 Frame = +3

Query: 222 KPPLFNMNAMSALYHIAQNESPTL-QSNEWSDYFRNFVDSCLQKIPQDRPTSEELLKHMF 280
           KPP  +++ M A++ I     P+  Q ++WS  F +FV  CL K P++R T+ +LL+H F
Sbjct: 348 KPPYGDIHPMRAIFMIPTKPPPSFRQPDKWSTEFIDFVSKCLVKNPENRATAVDLLQHDF 527

Query: 281 VLRERPETVLIDLIQRTKD 299
           + +     +L  +I+  K+
Sbjct: 528 IKKAEACEILQAMIREAKE 584
>00300
          Length = 2318

 Score =  140 bits (354), Expect = 2e-33,   Method: Compositional matrix adjust.
 Identities = 82/256 (32%), Positives = 131/256 (51%), Gaps = 8/256 (3%)
 Frame = -1

Query: 33   EIGHGSFGAVYFARDVRTNEVVAIKKMSYSGKQSTEKWQDIIKEVKFLQRIKHPNSIEYK 92
            +IG G FG VY A ++ T E++A+K+M +      ++ +++  E+K  + I+H N ++Y 
Sbjct: 1637 KIGEGQFGKVYTAVNMSTGELMALKEMKFQ-PNDLQQLREMCDEIKIFEGIQHENLVKYY 1461

Query: 93   GCYLREHTAWLVMEYCLGSASDLLEVHKKPLQEVEIAAITHGALQGLAYLHSHTMIHRDI 152
            G  + +    + MEYC      + E  K  L E  I   T   +  + +LH ++++HRDI
Sbjct: 1460 GVEVHKDEMLMFMEYC--DTGTIEEAAKMGLPEYLIRRYTREIVLAVNHLHENSIVHRDI 1287

Query: 153  KAGNILLTEPGQVKLADFGSA-------SMASPANSFVGTPYWMAPEVILAMDEGQYDGK 205
            K  NI LT  G VKL DFG +       +M    ++ VGT  +MAPEV    D+G Y   
Sbjct: 1286 KGANIFLTSNGHVKLGDFGCSVKLKSHTTMPGEFHNLVGTTAYMAPEVFTQNDQGGYGRA 1107

Query: 206  VDVWSLGITCIELAERKPPLFNM-NAMSALYHIAQNESPTLQSNEWSDYFRNFVDSCLQK 264
             D+WSLG   IE+A  K P  ++ N    +Y +     P +  +  S   ++F+D  +  
Sbjct: 1106 ADIWSLGCVVIEMATGKRPWHDLDNNYQIMYKVGIGHKPAV-PDSLSVEGKHFLDLIMCH 930

Query: 265  IPQDRPTSEELLKHMF 280
             P  R  + +LL H F
Sbjct: 929  DPAQRALASQLLDHTF 882
>14420
          Length = 528

 Score =  132 bits (332), Expect = 7e-31,   Method: Composition-based stats.
 Identities = 74/167 (44%), Positives = 99/167 (59%), Gaps = 5/167 (2%)
 Frame = +2

Query: 73  IIKEVKFLQRIKHPNSIEYKGCYLREHTAWLVMEYCLG-SASDLLEVHKKPLQEVEIAAI 131
           II E+  ++  ++PN + Y   YL     W+VME+  G S +D+  V +  + E +IAA+
Sbjct: 41  IINEILVMRENQNPNIVNYLDSYLVGEELWVVMEFLAGGSLTDV--VTETCMDEGQIAAV 214

Query: 132 THGALQGLAYLHSHTMIHRDIKAGNILLTEPGQVKLADFGSASMASPANS----FVGTPY 187
               LQ L +LH + +IHRDIK+ NILL   G VKL DFG  +  SP  S     VGTPY
Sbjct: 215 CRECLQALEFLHENQVIHRDIKSDNILLGMDGSVKLTDFGFCAQLSPEQSKRSTMVGTPY 394

Query: 188 WMAPEVILAMDEGQYDGKVDVWSLGITCIELAERKPPLFNMNAMSAL 234
           WMAPEV+      QY   VD+WSLG+ CIE+ E +PP  N N + AL
Sbjct: 395 WMAPEVV---TRKQYGPTVDIWSLGVMCIEMIEGEPPYLNENPLRAL 526
>13592
          Length = 980

 Score =  125 bits (315), Expect = 6e-29,   Method: Compositional matrix adjust.
 Identities = 88/267 (32%), Positives = 135/267 (50%), Gaps = 12/267 (4%)
 Frame = +2

Query: 33  EIGHGSFGAVYFARDVRTNEVVAIKKMSYSGKQSTEKWQDIIKEVKFLQRIKHPNSIEYK 92
           +IG G FG VY A +  T E++A+K+++    + T   +++ +E+K L+ IKH N + Y 
Sbjct: 5   KIGQGRFGKVYTAVNNNTGELMAMKEIAIQPGE-TRALKNVAEELKILEGIKHKNLVRYY 181

Query: 93  GCYLREHTAWLVMEYCL-GSASDLLEVHKKPLQEVEIAAITHGALQGLAYLHSHTMIHRD 151
           G  +      + ME C  G+   L+E+    L E      T   L G+A LH H ++HRD
Sbjct: 182 GIEVHREELLIFMELCSEGTLESLVEL-TGGLPEALSRRFTAQLLSGVAELHKHGIVHRD 358

Query: 152 IKAGNILLTE-PGQVKLADFGSA-------SMASPANSFVGTPYWMAPEVILAMDEGQYD 203
           IK  NI L +    +KL DFGSA       ++      +VGT  +MAPEV    +   + 
Sbjct: 359 IKTANIFLVDGSNSLKLGDFGSAVKIQAHTTVPGELQGYVGTQAYMAPEVFTKTNSDGHG 538

Query: 204 GKVDVWSLGITCIELAERKPPL--FNMNAMSALYHIAQNESPTLQSNE-WSDYFRNFVDS 260
              D+WS+G   +E+A  K P   F+ N    ++ +   E P  Q+ E  S    +F+D 
Sbjct: 539 RLADIWSVGCVVVEMASGKRPWAQFDSN-FQIMFKVGMGEKP--QAPESLSQEGHDFIDH 709

Query: 261 CLQKIPQDRPTSEELLKHMFVLRERPE 287
           CLQ  P+ R ++ ELL+  F    R E
Sbjct: 710 CLQHDPKQRLSAIELLEQNFCKSGRDE 790
>01707
          Length = 757

 Score =  105 bits (261), Expect = 1e-22,   Method: Composition-based stats.
 Identities = 64/195 (32%), Positives = 108/195 (55%), Gaps = 4/195 (2%)
 Frame = +1

Query: 28  FTDLREIGHGSFGAVYFARDVRTNEVVAIKKMSYSGKQSTEKWQDIIKEVKFLQRIKHPN 87
           +  + +IG GS+G V+  R+  T+++VAIKK   S      K +  ++E++ L+++KHPN
Sbjct: 70  YEKIGKIGEGSYGVVFKCRNKETSQLVAIKKFVESEDDPLIK-KIAMREIRMLKQLKHPN 246

Query: 88  SIEYKGCYLREHTAWLVMEYCLGSASDLLEVHKKPLQEVEIAAITHGALQGLAYLHSHTM 147
            +     + R+    LV +Y   +  + L+ + + L E  +  I +  L  + + H +  
Sbjct: 247 LVRLIEVFRRKKRLHLVFDYVDHTLLNELDRYPRGLPEPMVKRIIYQTLLAVNFCHQYNT 426

Query: 148 IHRDIKAGNILLTEPGQVKLADFGSAS-MASPANS---FVGTPYWMAPEVILAMDEGQYD 203
           IHRD+K  NIL+T  GQVKL DFG A  +  P +    +V T ++ APE+++   + QY 
Sbjct: 427 IHRDVKPENILITRQGQVKLCDFGFARILTGPGDEYTDYVATRWYRAPELLVG--DTQYG 600

Query: 204 GKVDVWSLGITCIEL 218
             VDVW++G    EL
Sbjct: 601 PPVDVWAIGCVFAEL 645
>06405
          Length = 1965

 Score =  100 bits (250), Expect = 2e-21,   Method: Compositional matrix adjust.
 Identities = 77/263 (29%), Positives = 129/263 (49%), Gaps = 16/263 (6%)
 Frame = +1

Query: 34  IGHGSFGAVYFARDVRTNEVVAIKKMSYSGKQSTEKWQDIIKEVKFLQRIKHPNSIEYKG 93
           +G G +G VY A   R N++VA+K +    K+ T    D ++E   ++ +KHPN ++  G
Sbjct: 283 LGGGQYGDVYEAMWKRYNKIVAVKTL----KEDTMALNDFLEEAAIMKEMKHPNLVQLLG 450

Query: 94  CYLREHTAWLVMEYCL-GSASDLLEVHKKPLQEVEIAAITHGALQ---GLAYLHSHTMIH 149
              RE   ++V E+   G+  D L    +  +E    A+ + A Q   G+AYL +   IH
Sbjct: 451 VCTREPPFYIVTEFMPHGNLLDYLRSSTR--EENGPTALMYMATQIASGMAYLETKNFIH 624

Query: 150 RDIKAGNILLTEPGQVKLADFGSASMA--SPANSFVGTPY---WMAPEVILAMDEGQYDG 204
           RD+ A N L+ +   VK+ADFG A +       + +G  +   W APE    +   ++  
Sbjct: 625 RDLAARNCLVADSNMVKVADFGLARLMKDDTYTAHIGAKFPIKWTAPE---GLAFNRFST 795

Query: 205 KVDVWSLGITCIELAERKPPLFNMNAMSALYHIAQN----ESPTLQSNEWSDYFRNFVDS 260
           + D+W+ G+   ELA      +    ++ +YH+ +     E P       +D +   +  
Sbjct: 796 RSDIWAFGVLLWELATYGMSPYPGVELTEVYHLLERGYRMERPPGTP---ADVYILML-K 963

Query: 261 CLQKIPQDRPTSEE---LLKHMF 280
           C Q  P+DRPT +E   LL++MF
Sbjct: 964 CWQWDPKDRPTFKEIHFLLENMF 1032
>01756
          Length = 1858

 Score = 97.8 bits (242), Expect = 2e-20,   Method: Compositional matrix adjust.
 Identities = 69/220 (31%), Positives = 110/220 (50%), Gaps = 15/220 (6%)
 Frame = -3

Query: 19   FFKEDPEKLFTDLREIGHGSFGAVYFARDVRTNEVVAIKKMSYSGKQSTEKWQDIIKEVK 78
            F  ED +  +  L +IG G+FG V+ AR  +T +VVA+KK+    ++        ++E+K
Sbjct: 1757 FCDEDAK--YEKLAKIGQGTFGEVFKARCKKTKQVVAMKKVLMDNEKEGFP-ITALREIK 1587

Query: 79   FLQRIKHPNSIE-YKGCYLREHTA-------WLVMEYCLGSASDLLEVHKKPLQEVEIAA 130
             LQ + H N ++  + C  +  +A       +LV E+C    + LL          EI  
Sbjct: 1586 ILQLLNHENVVDLIEICSTKATSANRYKSMFYLVFEFCEHDLAGLLSNMSVVFNLPEIKE 1407

Query: 131  ITHGALQGLAYLHSHTMIHRDIKAGNILLTEPGQVKLADFGSASMASP----ANSF---V 183
            +    + GL Y+H + ++HRD+KA NIL+T+ G +KLADFG A   S      N +   V
Sbjct: 1406 VMKQLMNGLYYIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRV 1227

Query: 184  GTPYWMAPEVILAMDEGQYDGKVDVWSLGITCIELAERKP 223
             T ++  PE++L   +  Y   +D W  G    E+  R P
Sbjct: 1226 VTLWYRPPELLLG--DRNYSTAIDQWGAGCIMAEMWTRNP 1113
>01060
          Length = 1800

 Score = 95.1 bits (235), Expect = 1e-19,   Method: Compositional matrix adjust.
 Identities = 65/236 (27%), Positives = 118/236 (50%), Gaps = 10/236 (4%)
 Frame = +1

Query: 28  FTDLREIGHGSFGAVYFARDVRTNEVVAIKKMSYSGKQSTEKWQDIIKEVKFLQRIKHPN 87
            TD ++IG G++G VY  R   T   +A+KK+   G +        I+E+  L+ ++H N
Sbjct: 79  LTDFQKIGEGTYGVVYKCRHRATGRKLAMKKIRLRGSEDGVP-SSAIREIAMLRELRHTN 255

Query: 88  SIEYKGCYLREHTAWLVMEYCLGSASDL-LEVHKKP----LQEVEIAAITHGALQGLAYL 142
            +  +   + +   +LV E+    + DL + + K P    L    + +     + G+ + 
Sbjct: 256 IVCLEDVIMEDERLFLVFEFL---SMDLKMYIDKFPEGVVLDRRLVKSYVFQIVTGIXFC 426

Query: 143 HSHTMIHRDIKAGNILLTEPGQVKLADFGSA-SMASPANSF---VGTPYWMAPEVILAMD 198
           H   ++HRD+K  N+L+   G +K+ADFG A + A P  ++   V T ++ APE++  M 
Sbjct: 427 HQRRIVHRDLKPQNLLINHTGAIKIADFGMARTFALPVRAYTHEVVTLWYRAPEIL--MG 600

Query: 199 EGQYDGKVDVWSLGITCIELAERKPPLFNMNAMSALYHIAQ-NESPTLQSNEWSDY 253
             +Y   VDVWS+G    ++  R P     + +  L+ I +   +PT Q+  W ++
Sbjct: 601 ASKYSTPVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIFRIIGTPTEQT--WPEF 762
>01718
          Length = 959

 Score = 94.7 bits (234), Expect = 1e-19,   Method: Compositional matrix adjust.
 Identities = 78/261 (29%), Positives = 127/261 (48%), Gaps = 14/261 (5%)
 Frame = +3

Query: 33  EIGHGSFGAVYFARDVRTNEVVAIKKMSYSGKQSTEKWQDIIKEVKFLQRIKHPNSIEYK 92
           +IG G F  V+      T +V+A+K  + +  +      ++++EV+ L R++H N + + 
Sbjct: 168 KIGAGFFSEVFKVTHRITGQVMALKMNTMTSNR-----HNMLREVQLLNRLQHANILRFM 332

Query: 93  GCYLREHTAWLVMEYC-LGSASDLLEVHKKPLQEVEIAAITHGALQGLAYLHSHTMIHRD 151
           G  + E     + EY   G+   LLE   + L   +   +T G  +GL YLHS   IHRD
Sbjct: 333 GVCVHEGQLHALTEYIPSGNLEQLLEKKDEELPWTQRIQLTLGLARGLDYLHSTRFIHRD 512

Query: 152 IKAGNILL----TEPGQVKLADFGSAS-MASPAN----SFVGTPYWMAPEVILAMDEGQY 202
           + + NIL+           +ADFG A+ +  P +      VG+PYWMAPEV   ++   Y
Sbjct: 513 LTSKNILIRREDNHGYHAVIADFGLATKIPDPLDKEKLPTVGSPYWMAPEV---LNGHFY 683

Query: 203 DGKVDVWSLGITCIELAERKPP----LFNMNAMSALYHIAQNESPTLQSNEWSDYFRNFV 258
           + + D++S+GI   E+  R P     +  MN     Y +A +E   + S    DY +   
Sbjct: 684 NERADLFSVGIIMCEITARIPADPDIMPRMNNFGVDY-VALSE---MISYCPLDYLQ-LA 848

Query: 259 DSCLQKIPQDRPTSEELLKHM 279
             C Q  PQ RP   E+++ +
Sbjct: 849 FKCCQVDPQKRPRGVEIIEWL 911
>14126
          Length = 1265

 Score = 93.6 bits (231), Expect = 4e-19,   Method: Compositional matrix adjust.
 Identities = 66/214 (30%), Positives = 112/214 (52%), Gaps = 12/214 (5%)
 Frame = +3

Query: 21  KEDPEKLFTDLREIGHGSFGAVYFARDVRT-NEVVAIKKMSYSGKQSTEKWQDI--IKEV 77
           ++  E+ + ++  IG+G++G VY ARD+R   E VA+K++  +  +       I  I  +
Sbjct: 174 RDSTEQKYEEVAVIGNGAYGTVYKARDLRNQGEFVAMKRIRLNNTEEGMPMMAIREISML 353

Query: 78  KFLQRIKHPN-----SIEYKGCYLREHTAWLVMEYCLGSASDLLEVHKKP-LQEVEIAAI 131
           K L++ +HPN      + +     RE    LV EY     +  L     P L    I  +
Sbjct: 354 KQLEQYEHPNVVRLLDVSHNTITDREIRLNLVFEYIEHDLATYLAKCPSPGLGPDRIKDL 533

Query: 132 THGALQGLAYLHSHTMIHRDIKAGNILLTEPGQVKLADFGSASMAS---PANSFVGTPYW 188
               L G+ +LHS+ ++HRD+K  N+L+++ G++KLADFG A + S      + V T ++
Sbjct: 534 MLQLLNGVDFLHSNRIVHRDLKPQNLLISKDGRLKLADFGLARIYSFHMALTTVVVTLWY 713

Query: 189 MAPEVILAMDEGQYDGKVDVWSLGITCIELAERK 222
            +PEV++   + +Y   VD+WS G    EL  R+
Sbjct: 714 RSPEVLM---QAEYGTSVDIWSCGCIFAELFTRR 806
>29581
          Length = 1278

 Score = 85.5 bits (210), Expect(2) = 3e-17,   Method: Compositional matrix adjust.
 Identities = 51/151 (33%), Positives = 78/151 (51%), Gaps = 6/151 (3%)
 Frame = -2

Query: 79   FLQRIKHPNSIEYKGCYLREH--TAWLVMEYCLGSASDLLEVHKKPLQEVEIAAITHGAL 136
            FL  ++H N ++ +   + +   + +LVMEYC    + LL+    P  E ++  I    L
Sbjct: 1196 FLLNLRHQNIVQLQEVVVGKSLDSLFLVMEYCEQDLASLLDNMPAPFSESQVKCIVLQLL 1017

Query: 137  QGLAYLHSHTMIHRDIKAGNILLTEPGQVKLADFGSASMAS----PANSFVGTPYWMAPE 192
            +GL YLH   +IHRD+K  N+L+T+ G VK+ADFG A        P    V T ++ APE
Sbjct: 1016 KGLRYLHEAFIIHRDLKVSNLLMTDKGCVKIADFGLARNYGKPQKPMTPKVVTLWYRAPE 837

Query: 193  VILAMDEGQYDGKVDVWSLGITCIELAERKP 223
            ++       +   +D+WS G    EL   KP
Sbjct: 836  LLFG--SKTHSTAIDMWSAGCILGELLGHKP 750

 Score = 21.9 bits (45), Expect(2) = 3e-17,   Method: Compositional matrix adjust.
 Identities = 8/15 (53%), Positives = 13/15 (86%)
 Frame = -1

Query: 51   NEVVAIKKMSYSGKQ 65
            NE+VA+KKM  +G++
Sbjct: 1278 NEIVALKKMRMTGER 1234
>04591
          Length = 1117

 Score = 85.5 bits (210), Expect = 9e-17,   Method: Compositional matrix adjust.
 Identities = 53/161 (32%), Positives = 86/161 (53%), Gaps = 11/161 (6%)
 Frame = -2

Query: 74   IKEVKFLQRIKHPNSIEYK-------GCYLR-EHTAWLVMEYCLGSASDLLEVHKKPLQE 125
            ++E+K LQ+++H N ++ +       G Y R + T +L+ EYC    + LL   +     
Sbjct: 1077 LREIKILQQLEHENVVQLQEICHTQAGPYNRYKSTFYLIFEYCDYDLAGLLNNLRVKFSL 898

Query: 126  VEIAAITHGALQGLAYLHSHTMIHRDIKAGNILLTEPGQVKLADFGSASMASPANSF--- 182
             +   +    L GL Y+H+  ++HRDIKA NILLT  G +KLADFG +     +      
Sbjct: 897  ADKKNLMSQLLNGLFYIHTKQILHRDIKAANILLTRDGVLKLADFGLSRPWVKSKRLTNR 718

Query: 183  VGTPYWMAPEVILAMDEGQYDGKVDVWSLGITCIELAERKP 223
            V T ++  PE++L   E +Y  ++D+W +G    E+  RKP
Sbjct: 717  VVTLWYRPPELLLG--EREYGPEIDMWGVGCIMAEMWSRKP 601
>00392
          Length = 668

 Score = 81.3 bits (199), Expect = 2e-15,   Method: Compositional matrix adjust.
 Identities = 59/172 (34%), Positives = 90/172 (52%), Gaps = 12/172 (6%)
 Frame = +3

Query: 76  EVKFLQRIKHPNSIEYKGCYLREH------TAWLVMEYCL-GSASDLLEVHKKPLQEVEI 128
           E + L+ ++HPN + +   Y  EH         LV E    G+    L+  KKP  ++ +
Sbjct: 81  EAEMLKELQHPNIVRFFD-YWEEHNHRNRKVIILVTELMTSGTLKTYLKRFKKPNVKI-L 254

Query: 129 AAITHGALQGLAYLHSHT--MIHRDIKAGNILLTEP-GQVKLADFGSASMA--SPANSFV 183
                  L+GL +LH+ T  +IHRD+K  NI +T P G VK+ D G A++   S A S +
Sbjct: 255 KNWCRQVLKGLYFLHTRTPPVIHRDLKCDNIFITGPTGSVKIGDLGLATLKNQSFAKSVI 434

Query: 184 GTPYWMAPEVILAMDEGQYDGKVDVWSLGITCIELAERKPPLFNMNAMSALY 235
           GTP +MAPE    M E  YD  VDV++ G+  +E+A  + P    +  + +Y
Sbjct: 435 GTPEFMAPE----MYEEHYDEAVDVYAFGMCMLEMASSEYPYSECSNAAQIY 578
>37602
          Length = 804

 Score = 77.8 bits (190), Expect(2) = 4e-15,   Method: Composition-based stats.
 Identities = 46/103 (44%), Positives = 54/103 (52%), Gaps = 1/103 (0%)
 Frame = -1

Query: 89  IEYKGCYLREHTAWLVMEYCLG-SASDLLEVHKKPLQEVEIAAITHGALQGLAYLHSHTM 147
           + Y   YLR    W+ MEYC G S  D+  V   PL E +IA +    L+GL YLH    
Sbjct: 330 VGYFDSYLRREKLWIAMEYCGGGSMQDIYHV-TGPLTEPQIAFVCRETLKGLHYLHRRGK 154

Query: 148 IHRDIKAGNILLTEPGQVKLADFGSASMASPANSFVGTPYWMA 190
           +HRDIK  NILLTE G VKLADF   S     N      +W A
Sbjct: 153 MHRDIKGANILLTEEGDVKLADFWRVSSNHSHNVQKKVFHWNA 25

 Score = 22.3 bits (46), Expect(2) = 4e-15,   Method: Compositional matrix adjust.
 Identities = 7/7 (100%), Positives = 7/7 (100%)
 Frame = -3

Query: 187 YWMAPEV 193
           YWMAPEV
Sbjct: 22  YWMAPEV 2

 Score = 31.2 bits (69), Expect(2) = 0.22,   Method: Composition-based stats.
 Identities = 13/27 (48%), Positives = 17/27 (62%), Gaps = 4/27 (14%)
 Frame = -1

Query: 168 ADFGSASMASPA----NSFVGTPYWMA 190
           ADFG ++  +       SF+GTPYWMA
Sbjct: 747 ADFGVSAQITATMCKRKSFIGTPYWMA 667

 Score = 21.9 bits (45), Expect(2) = 0.22,   Method: Composition-based stats.
 Identities = 10/12 (83%), Positives = 10/12 (83%)
 Frame = -2

Query: 156 NILLTEPGQVKL 167
           NILLTE G VKL
Sbjct: 803 NILLTEEGDVKL 768
>19301
          Length = 712

 Score = 78.2 bits (191), Expect = 1e-14,   Method: Compositional matrix adjust.
 Identities = 52/156 (33%), Positives = 87/156 (55%), Gaps = 4/156 (2%)
 Frame = +2

Query: 22  EDPEKLFTDLREIGHGSFGAVYFARDVRTNEVVAIKKMSYSGKQSTEKWQDIIK-EVKFL 80
           E P +  TDL  +G G+ GAV+  +     E VA+KK+           +DI + +++ L
Sbjct: 293 EIPFESITDLEWLGSGAQGAVFLGK--LCAEEVAVKKV-----------RDIKETDIRNL 433

Query: 81  QRIKHPNSIEYKGCYLREHTAWLVMEYCLGSASDLLEVHKKPLQEVEIAAITHGALQ--- 137
           +++ HPN I +KG   +     ++MEYC      L EV +   +E+  A +   + Q   
Sbjct: 434 RKLNHPNIISFKGVCTQAPCYCIIMEYC--PYGQLYEVLRDG-KEIPPALVLDWSKQIAS 604

Query: 138 GLAYLHSHTMIHRDIKAGNILLTEPGQVKLADFGSA 173
           G+ YLHSH +IHRD+K+ N+L+ +   VK++DFG++
Sbjct: 605 GMNYLHSHKIIHRDLKSPNVLVAKNDVVKISDFGTS 712
>00715
          Length = 1788

 Score = 75.9 bits (185), Expect = 7e-14,   Method: Compositional matrix adjust.
 Identities = 59/236 (25%), Positives = 105/236 (44%), Gaps = 36/236 (15%)
 Frame = +1

Query: 77  VKFLQRIKHPNSIEYKGC---YLREHTAWLVMEYCLGSAS--DLLEVHKKPLQEVEIAAI 131
           + F   ++H N +   G    +  E  AWL MEY +G  +   +L  H++ +      ++
Sbjct: 79  LAFRCGLRHVNVVSILGATSLHRFEDGAWLAMEY-VGPLNLQTILNDHQQDIDSSMRLSL 255

Query: 132 THGALQGLAYLHSHTMIHRDIKAGNILLTEPGQVKLADFGSASMASPA------------ 179
                +GL YLHS  ++H D+K  N LLT   ++++ADFG     +P             
Sbjct: 256 ALQMARGLHYLHSINIVHLDLKPANCLLTRDLKLRIADFGCCHQLTPTGLDMGEREGGMA 435

Query: 180 --------------NSFVGTPYWMAPEVILAMDEGQYDGKVDVWSLGITCIELAERKPPL 225
                         N   GT  + APE++  +   Q   + DV+SLGIT  ++  R+ P 
Sbjct: 436 GNELELTPVQGAWKNELAGTLAYRAPELLKGL---QPSVRSDVYSLGITLWQMCTRQGPY 606

Query: 226 FNMNAMSALYHIAQNE-----SPTLQSNEWSDYFRNFVDSCLQKIPQDRPTSEELL 276
             + A + +Y +   +      P+ + + +   FR+    C  +  +DRPTS +++
Sbjct: 607 EGVPAHAVVYQVVSKDLRPCPPPSTEDDPFEVMFRDLYTQCWARRVEDRPTSLDVV 774
>03240
          Length = 1683

 Score = 73.9 bits (180), Expect = 3e-13,   Method: Compositional matrix adjust.
 Identities = 60/254 (23%), Positives = 98/254 (38%), Gaps = 54/254 (21%)
 Frame = -3

Query: 27   LFTDLREIGHGSFGAVYFARDVRTNEVVAIKKMSYSGKQSTEKWQDIIKEVKFLQRIKHP 86
            +F  ++ +G G+FG V   R   T  + A+K +  S      +   +  E   L    + 
Sbjct: 1288 MFEKIKTLGVGAFGEVSLCRKNDTGMLYAMKTLRKSDVLKRNQVAHVKAERDILAEADNE 1109

Query: 87   NSIEYKGCYLREHTAWLVMEYCLGSASDLL------EVHKKPLQEVEIAAITHGALQGLA 140
              ++    +   +  + VM+Y  G   DL+      E+  +PL    +A +    +Q + 
Sbjct: 1108 WVVKLYYSFQDHNYLYFVMDYVPGG--DLMGLLIRMEILDEPLARFYVAEL----VQAIE 947

Query: 141  YLHSHTMIHRDIKAGNILLTEPGQVKLADFGSAS-------------------------- 174
             +H    IHRDIK  NIL+   G +KL DFG  +                          
Sbjct: 946  SVHRMGFIHRDIKPDNILIDRNGHIKLTDFGLCTGFRWTHNSKYYQRDGTHARQDSMEVK 767

Query: 175  ----------MASP------------ANSFVGTPYWMAPEVILAMDEGQYDGKVDVWSLG 212
                      +  P            A+S VGTP ++APEV+  +  G Y    D WS+G
Sbjct: 766  CQLDEQCQCEILKPLERRRKREQRCLAHSLVGTPNYIAPEVLSRL--GGYTSVCDWWSVG 593

Query: 213  ITCIELAERKPPLF 226
            +   E+    PP +
Sbjct: 592  VILFEMLVGHPPFY 551
>09606
          Length = 1300

 Score = 73.9 bits (180), Expect = 3e-13,   Method: Compositional matrix adjust.
 Identities = 73/286 (25%), Positives = 111/286 (38%), Gaps = 33/286 (11%)
 Frame = -3

Query: 28   FTDLREIGHGSFGAVYFARDVRTNEVVAIKKMSYSGKQSTEKWQDIIKEVKFLQRIKHPN 87
            F    E+G G    +Y  R   T   VAI  +         K  ++   V+    I HPN
Sbjct: 1109 FVLYEELGKGEHSIIYKGRRKGTINFVAIHCIEKC------KRPEVTNTVRMTHDISHPN 948

Query: 88   SIEYKGCYLREHTAWLVMEYCLG-SASDLLEVHKKPLQEVEIAAITHGALQGLAYLHSHT 146
             +++   Y   +  WLV+E C G S +D+L      L E  I       + GL Y+HS  
Sbjct: 947  VVQFHEWYETSNHLWLVVELCTGGSLADIL-AQDHHLPETSIRDFGIHLVTGLHYIHSLG 771

Query: 147  MIHRDIKAGNILLTEPGQVKLADFGSASM------------ASPANSF------------ 182
            ++  D++   +LL   G +K ADFG + +            A   + +            
Sbjct: 770  ILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEAGDQWNIQSAEEMMKQV 591

Query: 183  --VGTPYWMAPEVILAMDEGQYDGKVDVWSLGITCIELAERKPPLFNMNAMSALYHIAQN 240
               G+P +MAPEV    +        D+W+LG    E+    PP            +   
Sbjct: 590  PTSGSPTYMAPEVFQGAEPSIMS---DLWALGCVFYEMFSGHPPFLGETYDITKDKVLNK 420

Query: 241  ESPTLQ------SNEWSDYFRNFVDSCLQKIPQDRPTSEELLKHMF 280
            E P  +      S + S  F N ++S LQK    R +   L+KH F
Sbjct: 419  EFPLPKVKGSRLSAKPSPEFLNLLESLLQKDSTRRLSWASLVKHAF 282
>30755
          Length = 1137

 Score = 72.8 bits (177), Expect = 6e-13,   Method: Compositional matrix adjust.
 Identities = 45/143 (31%), Positives = 73/143 (51%), Gaps = 6/143 (4%)
 Frame = +2

Query: 133 HGA--LQGLAYLHSHTMIHRDIKAGNILLTEPGQVKLADFG----SASMASPANSFVGTP 186
           +GA  +  L YLHS  +I+RD+K  N+LL + G +K+ADFG      +      +F GTP
Sbjct: 47  YGAEIISALGYLHSQGIIYRDLKLENLLLDKDGHIKVADFGLCKEDITYGRTTKTFCGTP 226

Query: 187 YWMAPEVILAMDEGQYDGKVDVWSLGITCIELAERKPPLFNMNAMSALYHIAQNESPTLQ 246
            ++APEV   +D+  Y   VD W  G+   E+   + P +N +    L+ +   E     
Sbjct: 227 EYLAPEV---LDDNDYGRAVDWWGTGVVMYEMICGRLPFYNRDH-DVLFTLILVEDVKFP 394

Query: 247 SNEWSDYFRNFVDSCLQKIPQDR 269
            N  +D  ++ +   L K P++R
Sbjct: 395 RN-ITDEAKSLLSGLLAKDPRNR 460
>04852
          Length = 1462

 Score = 70.1 bits (170), Expect = 5e-12,   Method: Compositional matrix adjust.
 Identities = 66/253 (26%), Positives = 104/253 (41%), Gaps = 44/253 (17%)
 Frame = +1

Query: 71  QDIIKEVKFLQRIK----HPNSIEYKGCYLREHTAWLVMEYCL-GSASDLLE-------- 117
           QD ++E++ ++ +K    H N + + GC  +    W+++E+   G+  D LE        
Sbjct: 73  QDFVQELQVMKAVKKMGSHINIVNFLGCCTQGGPLWVIVEFAKNGNLRDFLESCRDGING 252

Query: 118 ------------VHKKPLQEV----EIAAITHGALQGLAYLHSHTMIHRDIKAGNILLTE 161
                         K P   V     + +      +G+ +L S   IHRD+ A N+L+TE
Sbjct: 253 YGKFVSPQDPGWYTKTPGGHVIRRKNLLSYAFQIARGMEFLASRKCIHRDLAARNVLVTE 432

Query: 162 PGQVKLADFGSASMASPANSFVG--TPY-WMAPEVILAMDEGQYDGKVDVWSLGITCIEL 218
              +K+ADFG +          G   P  WMAPE +  M   +Y  K DVWS G+   E 
Sbjct: 433 EHVLKIADFGLSRTGDYYKKRSGGRLPVKWMAPEALFDM---RYTTKSDVWSFGVVLWE- 600

Query: 219 AERKPPLFNMNAMSALYHIAQNESPTLQSNEWSDYFR------------NFVDSCLQKIP 266
                 +F++  M   Y    NE   L S    D +R              ++ C    P
Sbjct: 601 ------IFSLGGMP--YASIPNEE--LYSKLLDDAYRMPRPELASGNLYAIMERCWLNRP 750

Query: 267 QDRPTSEELLKHM 279
            DRP   +L+ H+
Sbjct: 751 SDRPEFSQLVGHI 789
>21808
          Length = 1011

 Score = 69.7 bits (169), Expect = 6e-12,   Method: Compositional matrix adjust.
 Identities = 52/170 (30%), Positives = 84/170 (49%), Gaps = 6/170 (3%)
 Frame = +1

Query: 54  VAIKKMSYSGKQSTEKWQDIIKEVKFLQRIKHPNSIEYKGCYLREHTAWLVMEYCL-GSA 112
           VAIK +    K  T   +D + E + +++++HP  I+      ++   +++ E    GS 
Sbjct: 28  VAIKTL----KSGTMDPKDFLAEAQIMKKLRHPKLIQLYAVCTQDDPIFIITELMKNGSL 195

Query: 113 SDLLEVHKKPLQEVEIAAITHGALQGLAYLHSHTMIHRDIKAGNILLTEPGQVKLADFGS 172
            + L+   + L+   +  I      G+AYL S   IHRD+ A NIL+++   VK+ADFG 
Sbjct: 196 LEFLQGKGRVLKLPALIDIGAQIACGMAYLESQNYIHRDLAARNILVSDNNTVKIADFGL 375

Query: 173 ASMA--SPANSFVGTPY---WMAPEVILAMDEGQYDGKVDVWSLGITCIE 217
           A +       + VG  +   W APE   A +  ++  K DVWS GI   E
Sbjct: 376 ARVIKEDEYEARVGARFPIKWTAPE---AANYNRFTIKSDVWSFGILLTE 516
>15910
          Length = 1361

 Score = 68.2 bits (165), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 48/155 (30%), Positives = 76/155 (49%), Gaps = 9/155 (5%)
 Frame = +2

Query: 136 LQGLAYLHSHTMIHRDIKAGNIL---LTEPGQVKLADFGSASMASP---ANSFVGTPYWM 189
           L G+ Y+H++ ++HRD+K  N+L   +T+  ++KLADFG + +  P    ++  GTP + 
Sbjct: 494 LHGVQYIHANGVVHRDLKPENLLYECMTDDSKLKLADFGLSRIIEPEVQMSTVCGTPGYC 673

Query: 190 APEVILAMDEGQYDGKVDVWSLGITCIELAERKPPLFNMNAMSALYHIAQNESPTLQSNE 249
           APEV   +   +Y   VD+WS+G+    L     P F  N       I + E        
Sbjct: 674 APEV---LKGDKYTPSVDMWSVGVIAYILLCGYEPFFAENEFEMYRKIIKGEY-KFDEEY 841

Query: 250 WSDYFRN---FVDSCLQKIPQDRPTSEELLKHMFV 281
           WS+   N    V   L   P+ R T+ E L+  +V
Sbjct: 842 WSEISENAKDVVRKLLVIDPKKRLTATEALRLPWV 946
>18484
          Length = 635

 Score = 67.8 bits (164), Expect = 2e-11,   Method: Composition-based stats.
 Identities = 34/92 (36%), Positives = 51/92 (55%), Gaps = 4/92 (4%)
 Frame = +1

Query: 138 GLAYLHSHTMIHRDIKAGNILLTEPGQVKLADFG--SASMASPAN--SFVGTPYWMAPEV 193
           GL +LH   +I+RD+K  N++L   G +K+ADFG     M   A   +F GTP ++APE+
Sbjct: 79  GLFFLHDQGIIYRDLKLDNVMLDSEGHIKIADFGMCKEGMTGDATTRTFCGTPDYIAPEI 258

Query: 194 ILAMDEGQYDGKVDVWSLGITCIELAERKPPL 225
           +L      Y   VD W+ G+   E+   +PP 
Sbjct: 259 VLYQ---PYSKSVDWWAYGVLLFEMLAGQPPF 345
>31885
          Length = 529

 Score = 66.2 bits (160), Expect = 7e-11,   Method: Composition-based stats.
 Identities = 57/172 (33%), Positives = 88/172 (51%), Gaps = 11/172 (6%)
 Frame = -2

Query: 77  VKFLQRIKHPNSIEYKGCYLREHTAWLVMEYCLGSASDLLEVHKKPLQEVEIAA------ 130
           V  L R+ HP  +     +  E   ++V++  LG     L  H +  QEV          
Sbjct: 519 VDMLTRLDHPFLVNLWYAFQDEEDLFMVVDLFLGGD---LRYHMQ--QEVSFREDCVKFY 355

Query: 131 ITHGALQGLAYLHSHTMIHRDIKAGNILLTEPGQVKLADFGSASMASP---ANSFVGTPY 187
           +   AL  L YL S  ++HRDIK  NILL E G   + DF  A+       A S  GT  
Sbjct: 354 LCQLALV-LDYLRSQKIVHRDIKPDNILLDEQGHCHVTDFNIATQLEDDELATSTSGTRP 178

Query: 188 WMAPEVI-LAMDEGQ-YDGKVDVWSLGITCIELAERKPPLFNMNAMSALYHI 237
           +MAPEV  +A++E + Y   VD WSLG++  EL +++ P F++++ ++L+ +
Sbjct: 177 YMAPEVYGVAINERRGYGFPVDWWSLGVSLFELLKKRRP-FSVHSNTSLHEM 25
>19761
          Length = 473

 Score = 65.9 bits (159), Expect = 8e-11,   Method: Composition-based stats.
 Identities = 44/133 (33%), Positives = 69/133 (51%), Gaps = 6/133 (4%)
 Frame = -3

Query: 138 GLAYLHSHT--MIHRDIKAGNILLTEPGQVKLADFGSA-SMASPAN---SFVGTPYWMAP 191
            L Y+H+HT  ++HRD+K  NI +TE G V+L D G A  +  PA+   S VGT  +++P
Sbjct: 387 ALNYMHTHTPVILHRDLKPQNIYVTEKGDVRLGDLGLARKLTGPADFATSQVGTIMYLSP 208

Query: 192 EVILAMDEGQYDGKVDVWSLGITCIELAERKPPLFNMNAMSALYHIAQNESPTLQSNEWS 251
           E+   + +  Y+ K D+WSLG    ++  +K     M  M  L  +       L  + +S
Sbjct: 207 EI---LSQQPYNSKSDIWSLGCVFYDITGKKGS-DEMGVMFLLVQVMGGRKLPL-PDHYS 43

Query: 252 DYFRNFVDSCLQK 264
             FR+ +   L K
Sbjct: 42  QEFRDTISRMLTK 4
>14116
          Length = 1017

 Score = 65.5 bits (158), Expect = 9e-11,   Method: Compositional matrix adjust.
 Identities = 61/204 (29%), Positives = 88/204 (43%), Gaps = 15/204 (7%)
 Frame = -1

Query: 33  EIGHGSFGAVYFARDVRT------NEVVAIKKMSYSGKQSTEKWQDIIKEVKFLQRIKHP 86
           EIG G+FG V   R   T      + +VA+K +  +  +  E  Q  ++E   ++   H 
Sbjct: 615 EIGKGNFGCV--KRGFLTLPEQKGDILVAVKTLHNNNPREIEL-QSFLQEALIMKDFHHS 445

Query: 87  NSIEYKGCYLREHTAWLVMEYCLGSASDLLEVHKKPLQEVEIAAITHGA--LQGLAYLHS 144
           N +   G  L      LV+   +     L  +     Q      I +G    +G+ YL  
Sbjct: 444 NVLTLIGICLNLDDMPLVVLPFMKHGDLLTYIRDDQHQPTIKDLIMYGVDIARGMDYLAG 265

Query: 145 HTMIHRDIKAGNILLTEPGQVKLADFGSA------SMASPANSFVGTPY-WMAPEVILAM 197
              +HRD+ A N +L E   VK+ADFG A         S  N     P  WMA E   ++
Sbjct: 264 LKFVHRDLAARNCMLDEDFHVKVADFGLARDIYEKEYYSSENKKAKLPVKWMALE---SL 94

Query: 198 DEGQYDGKVDVWSLGITCIELAER 221
           ++G YD K DVWS G+   EL  R
Sbjct: 93  EKGNYDSKTDVWSYGVVLWELLTR 22
>09007
          Length = 1440

 Score = 64.7 bits (156), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 64/296 (21%), Positives = 120/296 (40%), Gaps = 18/296 (6%)
 Frame = -1

Query: 32  REIGHGSFGAVYFA-RDVRTNEVVAIKKMSYSGKQSTEKWQDIIKEVKFLQRIKHPNSIE 90
           + +G G FG V  A     + E V +     S  +  +  Q+ +KE   +Q + H N + 
Sbjct: 861 KSLGQGHFGTVRQAIWTAESGEKVQVAVKCLSKDKIHKDGQEFLKETAIMQMLDHENIVR 682

Query: 91  YKGCYLREHTAWLVMEYCLGSASDLLEVHKKPLQEVEIAA-----ITHGALQGLAYLHSH 145
             G  + ++ A +++   L     LLE  K+    V+ +       +     G++YL S 
Sbjct: 681 VYGVVM-DNGADIMLVTELAPMRSLLECVKEVSARVDFSVPRLCDFSQQVCDGMSYLESK 505

Query: 146 TMIHRDIKAGNILLTEPGQVKLADFGSASMASPANSFV---------GTPYWMAPEVILA 196
            ++HRD+ A NILL    +VK++D G +        +              W APE    
Sbjct: 504 RLVHRDLAARNILLFSKSKVKISDVGVSGALGAGKEYYQSQQTIHLQNAVAWCAPESFRN 325

Query: 197 MDEGQYDGKVDVWSLGITCIELAERK-PPLFNMNAMSALYHIAQNESPTLQSNEWS--DY 253
           +    +    DVW+ G+   E       P   +N    +  +   +S  L+  +    +Y
Sbjct: 324 L---CFSSASDVWAFGVLLWEFFTHGFQPWAGLNGQQIMEAVDAPQSQRLEQPDLCPKEY 154

Query: 254 FRNFVDSCLQKIPQDRPTSEELLKHMFVLRERPETVLIDLIQRTKDAVRELDNLQY 309
           +   +  C ++ PQ RPT  +L    F+   +   + +  ++    +  + D+L Y
Sbjct: 153 YAVML-KCWEQEPQRRPTFSQL----FLTLPQIRPIQVKAVKDAPSSTPDKDHLHY 1
>11780
          Length = 1713

 Score = 64.3 bits (155), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 49/167 (29%), Positives = 82/167 (49%), Gaps = 6/167 (3%)
 Frame = +3

Query: 34  IGHGSFGAVYFARDVRTNEVVAIKKMSYSGKQSTEKWQDIIKEVKFLQRIKHPNSIEYKG 93
           IG G FG VY  + +   + VAIK++    K      Q  ++E   +  ++H N +   G
Sbjct: 621 IGKGDFGDVY--KGMYRGQPVAIKQL----KDKDRGEQSFLQEASVMTSLRHDNLVRLIG 782

Query: 94  CYLREHTAWLVMEYCL-GSASDLLEVHKKPL----QEVEIAAITHGALQGLAYLHSHTMI 148
             L E T +LV E+   G+  + L    + +     ++  A  T  A++   YL S  ++
Sbjct: 783 VVLGE-TIFLVTEFMGKGNLVEYLRSRGRSVITKKDQINFATDTCAAME---YLESKRLV 950

Query: 149 HRDIKAGNILLTEPGQVKLADFGSASMASPANSFVGTPY-WMAPEVI 194
           HRD+ A N+L+ + G+ K++DFG A     + + V  P  W APE +
Sbjct: 951 HRDLAARNVLVHDDGKAKVSDFGLAKFGDFSQTSVKFPIKWTAPEAL 1091
>01966
          Length = 1735

 Score = 58.9 bits (141), Expect(2) = 3e-10,   Method: Compositional matrix adjust.
 Identities = 40/156 (25%), Positives = 78/156 (50%), Gaps = 9/156 (5%)
 Frame = -1

Query: 50   TNEVVAIKKMSYSGKQSTEKWQDIIKEVKFLQRIKHPNSIEYKGCYLREHTAWLVMEYCL 109
            T   +A+KK+   G +        I+E+  L+ ++H N +  +   + +   +LV E+  
Sbjct: 1639 TGRKLAMKKIRLRGSEDGVP-SSAIREIAMLRELRHTNIVCLEDVIMEDERLFLVFEFL- 1466

Query: 110  GSASDL-LEVHKKP----LQEVEIAAITHGALQGLAYLHSHTMIHRDIKAGNILLTEPGQ 164
              + DL + + K P    L    + +     + G+ + H   ++HRD+K  N+L+   G 
Sbjct: 1465 --SMDLKMYIDKFPEGVVLDRRLVKSYVFQIVTGINFCHQRRIVHRDLKPQNLLINHTGA 1292

Query: 165  VKLADFGSA-SMASPANSF---VGTPYWMAPEVILA 196
            +K+ADFG A + A P  ++   V T ++ APE+++ 
Sbjct: 1291 IKIADFGMARTFALPVRAYTHEVVTLWYRAPEILMG 1184

 Score = 25.0 bits (53), Expect(2) = 3e-10,   Method: Compositional matrix adjust.
 Identities = 15/54 (27%), Positives = 27/54 (50%), Gaps = 1/54 (1%)
 Frame = -3

Query: 201  QYDGKVDVWSLGITCIELAERKPPLFNMNAMSALYHIAQ-NESPTLQSNEWSDY 253
            +Y   VDVWS+G    ++  R P     + +  L+ I +   +PT Q+  W ++
Sbjct: 1178 KYSTPVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIFRIIGTPTEQT--WPEF 1023
>01392
          Length = 1806

 Score = 62.0 bits (149), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 55/199 (27%), Positives = 86/199 (43%), Gaps = 31/199 (15%)
 Frame = -1

Query: 123  LQEVEIAAITHGALQGLAYLHSHTMIHRDIKAGNIL---LTEPGQVKLADFGSASMASPA 179
            L E E + +     + L +LHS  + HRD+K  NIL   L +   VK+ DF  AS  S  
Sbjct: 1800 LCEREASLVVRHIARALDFLHSKGIAHRDLKPENILCEHLDDVVPVKICDFDLASGISCD 1621

Query: 180  N---------SFVGTPYWMAPEVILAM--DEGQYDGKVDVWSLGITCIELAERKPPLFNM 228
                      + VG+  +MAPEV+ A   D   YD + D+WSLGI    +    PP +  
Sbjct: 1620 GDGTKTPELLTPVGSAEYMAPEVVDAWVGDSFSYDKRCDLWSLGIILYIMLCGYPPFYGQ 1441

Query: 229  --------------NAMSALYHIAQNESPTLQSNEW---SDYFRNFVDSCLQKIPQDRPT 271
                          +    L++  Q+      S EW   S   ++ +   L + P+ R +
Sbjct: 1440 CGEDCGWNRGEACHDCQDMLFNSIQDGHYKFPSQEWTSISSSAKDLIRHLLVREPRKRYS 1261

Query: 272  SEELLKHMFVLRERPETVL 290
            + ++LKH ++      T L
Sbjct: 1260 AADVLKHPWICTPPAATQL 1204
>27546
          Length = 426

 Score = 61.6 bits (148), Expect = 2e-09,   Method: Composition-based stats.
 Identities = 37/101 (36%), Positives = 53/101 (52%), Gaps = 2/101 (1%)
 Frame = -1

Query: 75  KEVKFLQRIKHPNSIEYKGCYLREHTAWLVMEYCLGSASDLLEVHKK--PLQEVEIAAIT 132
           +E++ L R+ HPN I+      R    ++ M Y      D+L   KK  P+ E +     
Sbjct: 333 RELEILTRLDHPNIIQIHSILQRGPKIFIFMRY--AEKGDMLSHIKKTGPIDEAQTKVWF 160

Query: 133 HGALQGLAYLHSHTMIHRDIKAGNILLTEPGQVKLADFGSA 173
               + L YLHSH + HRD+K  NILL++   VK+ADFG A
Sbjct: 159 FQMAKALQYLHSHDIAHRDLKCENILLSKRLNVKIADFGFA 37
>21079
          Length = 878

 Score = 61.2 bits (147), Expect = 2e-09,   Method: Composition-based stats.
 Identities = 42/139 (30%), Positives = 66/139 (47%), Gaps = 8/139 (5%)
 Frame = +1

Query: 85  HPNSIEYKGCYLREHTAWLVMEYCLGSASDLLEVHKKP---LQEVEIAAITHGALQGLAY 141
           HP  +     +    T  LVME+    A +L E   +    L E +          G+ Y
Sbjct: 1   HPKLLMLWDAFEAPRTMVLVMEFV--GAGELFERVIRDDFVLTERDCVHFVRQICSGVGY 174

Query: 142 LHSHTMIHRDIKAGNILLTE--PGQVKLADFGSASMASPANS---FVGTPYWMAPEVILA 196
           +H+ +++H D+K  N+L       Q+K+ DFG A    P +S     GTP ++APEV+  
Sbjct: 175 MHTQSILHLDLKPENVLCVSDNSNQIKIIDFGLARFYKPGDSLQVLFGTPEFIAPEVV-N 351

Query: 197 MDEGQYDGKVDVWSLGITC 215
            DE  +    D+WS+G+ C
Sbjct: 352 YDEINF--TTDMWSIGVIC 402
>26560
          Length = 398

 Score = 60.8 bits (146), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 37/95 (38%), Positives = 54/95 (56%), Gaps = 4/95 (4%)
 Frame = -1

Query: 135 ALQGLAYLHSHTMIHRDIKAGNILLTEPGQVKLADFGSASMAS---PANSFVGTPYWMAP 191
            + GL ++HS  +++RD+K  NILL E G V+++D G A   S   P  S VGT  +MAP
Sbjct: 329 VMLGLEHMHSRFVVYRDLKPANILLDENGHVRISDLGLACDFSKKRPHAS-VGTHGYMAP 153

Query: 192 EVILAMDEGQ-YDGKVDVWSLGITCIELAERKPPL 225
           EV++   +GQ YD   D +S G    +L +   P 
Sbjct: 152 EVLM---KGQSYDSSADWFSFGCMLYKLLKGHSPF 57
>07291
          Length = 833

 Score = 60.5 bits (145), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 31/91 (34%), Positives = 49/91 (53%), Gaps = 7/91 (7%)
 Frame = +1

Query: 138 GLAYLHSHTMIHRDIKAGNILLTEPGQVKLADFGSASMASPANSFVG--TPY-----WMA 190
           G+AYL    ++HR++ A N ++TE G+++L+D+G      P + +    +P      WMA
Sbjct: 85  GMAYLQEVKVVHRNLAARNCIVTEDGRLQLSDYGVTGSLFPQSYYTADDSPARDLVKWMA 264

Query: 191 PEVILAMDEGQYDGKVDVWSLGITCIELAER 221
           PE I   D   +  K DVW+ G+   EL  R
Sbjct: 265 PETI---DNFHFSSKSDVWAFGVVLWELLTR 348
>13066
          Length = 551

 Score = 58.9 bits (141), Expect = 1e-08,   Method: Composition-based stats.
 Identities = 44/148 (29%), Positives = 69/148 (46%), Gaps = 10/148 (6%)
 Frame = +3

Query: 75  KEVKFLQRIKHPNSIEYKGCYLREHTAWLVMEYCLGSASDLLEVHKKP--LQEVEIAAIT 132
           +E+  L ++ HP  I+      R    ++ M +      DLL   ++   ++E +     
Sbjct: 123 RELDLLTKLDHPYIIQIHSILQRXPKNFIFMRF--AERGDLLTYIQEVGFVKEKQAKIWF 296

Query: 133 HGALQGLAYLHSHTMIHRDIKAGNILLTEPGQVKLADFGSASMASP-------ANSFVGT 185
           +     L YLHS+ + HRD+K  NILL+    VKLADFG A            + ++ G+
Sbjct: 297 YQMTTALNYLHSYDVAHRDLKCENILLSSHFNVKLADFGFACACITESGEKYMSRTYCGS 476

Query: 186 PYWMAPEVILAMDEGQYDGKV-DVWSLG 212
             + APE++       Y  KV D WSLG
Sbjct: 477 AAYAAPEIVYG---APYAPKVADAWSLG 551
>03508
          Length = 1463

 Score = 58.2 bits (139), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 33/107 (30%), Positives = 56/107 (52%), Gaps = 4/107 (3%)
 Frame = +1

Query: 123 LQEVEIAAITHGALQGLAYLHSHTMIHRDIKAGNILLT-EPGQVKLADFGSASMASPA-- 179
             + +I    +  ++ L + HS  ++HRD+K  N+++  E  +++L D+G A    P   
Sbjct: 862 FTDYDIRFYLYELMKALDFCHSMGIMHRDVKPHNVMIDHENKKLRLIDWGLAEFYHPGME 1041

Query: 180 -NSFVGTPYWMAPEVILAMDEGQYDGKVDVWSLGITCIELAERKPPL 225
            N  V + Y+  PE++L  D   YD  +D+WSLG     +  RK PL
Sbjct: 1042YNVRVASRYFKGPELLL--DYQMYDYSLDMWSLGCMFASMIFRKEPL 1176
>04138
          Length = 800

 Score = 57.8 bits (138), Expect = 2e-08,   Method: Composition-based stats.
 Identities = 38/117 (32%), Positives = 60/117 (51%), Gaps = 7/117 (5%)
 Frame = +1

Query: 130 AITHGALQGLAYLHSHTMIHRDIKAGNILLTEPGQVKLADFG-----SASMASPA--NSF 182
           +I   A + L Y+H + ++HRD+KA NIL+T+ G +KLADFG     S ++  P    + 
Sbjct: 25  SIC*AADERLYYIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNR 204

Query: 183 VGTPYWMAPEVILAMDEGQYDGKVDVWSLGITCIELAERKPPLFNMNAMSALYHIAQ 239
           V T ++  PE++L   +  Y   +D W  G    E+  R P +      + L  I Q
Sbjct: 205 VVTLWYRPPELLLG--DRNYSTAIDQWGAGCIMAEMWTRNPIMQGTTEQNQLTLITQ 369
>21210
          Length = 518

 Score = 57.4 bits (137), Expect = 3e-08,   Method: Composition-based stats.
 Identities = 47/126 (37%), Positives = 62/126 (49%), Gaps = 5/126 (3%)
 Frame = +3

Query: 186 PYWMAPEVI--LAMDEGQYDGKVDVWSLGITCIELAERKPPLFN-MNAMSALYHIAQNES 242
           PY MAPE I   A   G YD + DVWSLGIT +ELA  + P    ++    L  + +  +
Sbjct: 15  PY-MAPERIDPRASSHG-YDVRSDVWSLGITLMELATGRFPYRKWVSIFDQLQQVVRGVA 188

Query: 243 PTL-QSNEWSDYFRNFVDSCLQKIPQDRPTSEELLKHMFV-LRERPETVLIDLIQRTKDA 300
           P L     +S  F NFV+ CL K  + RP   +LL H FV L E  E  +   +    D 
Sbjct: 189 PCLPHDGAFSHDFVNFVNKCLTKDEKQRPKYNKLLAHPFVRLYEEQEVDVASYVCNVLDK 368

Query: 301 VRELDN 306
            + L N
Sbjct: 369 RKTLQN 386
>17975
          Length = 449

 Score = 56.6 bits (135), Expect = 5e-08,   Method: Composition-based stats.
 Identities = 39/140 (27%), Positives = 69/140 (49%), Gaps = 4/140 (2%)
 Frame = +3

Query: 39  FGAVYFARDVRTNEVVAIKKMSYSGKQSTEKWQDIIKEVKFLQRIKHPNSIEYKGCYLRE 98
           F  V  AR V T E VA+K +  +      +   + +EV+ ++ ++HPN +        +
Sbjct: 6   FAVVKLARHVFTGEKVAVKVIDKTKLDEVSR-SHLFQEVRCMKLVQHPNVVRLYEVIDTQ 182

Query: 99  HTAWLVMEYCLGSASDLLEV---HKKPLQEVEIAAITHGALQGLAYLHSHTMIHRDIKAG 155
              +L++E  LG   D+ +    H   L+E          ++ ++Y H   ++HRD+K  
Sbjct: 183 TKLYLILE--LGDGGDMYDYIMRHSGGLEEKLAKRYFRQIVEAISYCHKLHVVHRDLKPE 356

Query: 156 NILLTE-PGQVKLADFGSAS 174
           N++  E PG VKL DFG ++
Sbjct: 357 NVVFFEKPGLVKLTDFGFST 416
>28157
          Length = 400

 Score = 56.6 bits (135), Expect = 5e-08,   Method: Compositional matrix adjust.
 Identities = 43/129 (33%), Positives = 69/129 (53%), Gaps = 8/129 (6%)
 Frame = +3

Query: 54  VAIKKMSYSGKQSTEKWQDIIKEVKFLQRIKHPNSIE-YKGCYLREHTAWLVMEYCLGSA 112
           VA+K++     +S ++ +  ++E+K L R+ HPN +  Y  C  R+H   LVMEY  G +
Sbjct: 9   VAVKRI-----ESEQEKKSFMQELKQLSRVSHPNIVCLYGAC--RDHPVCLVMEYAEGGS 167

Query: 113 SDLLEVHKKPLQEVEIAAITHGALQ---GLAYLHS---HTMIHRDIKAGNILLTEPG-QV 165
              +     P  +   A   +  LQ   G+ YLH      +IHRD+K  N+LL + G ++
Sbjct: 168 LYNVLHGSGPQPQYTAAHAMNWLLQCALGVEYLHGMKPKALIHRDLKPPNLLLIQCGTKL 347

Query: 166 KLADFGSAS 174
           K+ DFG+A 
Sbjct: 348 KICDFGTAC 374
>21433
          Length = 590

 Score = 55.5 bits (132), Expect = 1e-07,   Method: Composition-based stats.
 Identities = 38/91 (41%), Positives = 52/91 (57%), Gaps = 3/91 (3%)
 Frame = +2

Query: 138 GLAYLHSHTMIHRDIKAGNILLTEPGQVKLADFGSASMA--SPANSFVGTPYWMAPEVIL 195
            L Y H   +IHRDIK  N+LL   G +K+ADFG +  A  S   +  GT  ++ PE++ 
Sbjct: 203 ALEYCHYRKVIHRDIKPENLLLGLKGDLKIADFGWSVHAPSSRRTTMCGTLDYLPPEMV- 379

Query: 196 AMDEGQ-YDGKVDVWSLGITCIELAERKPPL 225
              EG+ +D  VD+WSLG+ C E     PPL
Sbjct: 380 ---EGKTHDENVDLWSLGVLCYEFLVGTPPL 463
>28638
          Length = 1458

 Score = 55.5 bits (132), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 29/82 (35%), Positives = 48/82 (58%), Gaps = 3/82 (3%)
 Frame = -1

Query: 147 MIHRDIKAGNILLTEP--GQVKLADFGSAS-MASPANSFVGTPYWMAPEVILAMDEGQYD 203
           +IH D+K  NILL  P    +K+ DFGS+  +      ++ + ++ +PEV+L +    YD
Sbjct: 768 IIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGVP---YD 598

Query: 204 GKVDVWSLGITCIELAERKPPL 225
             +D+WSLG   +E+   +PPL
Sbjct: 597 LAIDMWSLGCILVEMHTGEPPL 532
>27405
          Length = 532

 Score = 55.1 bits (131), Expect = 1e-07,   Method: Composition-based stats.
 Identities = 35/87 (40%), Positives = 50/87 (57%), Gaps = 4/87 (4%)
 Frame = -3

Query: 125 EVEIAAITHGALQGLAYLHSHTMIHRDIKAGNILLTEPGQVKLADFGSA---SMASPANS 181
           E E+       + GL ++HS  +++RD+K  NILL E G V+++D G A   S   P  S
Sbjct: 257 EKEVRFYAAEVMLGLEHMHSRFVVYRDLKPANILLDENGHVRISDLGLACDFSKKKPHAS 78

Query: 182 FVGTPYWMAPEVILAMDEGQ-YDGKVD 207
            VGT  +MAPEV++   +GQ YD   D
Sbjct: 77  -VGTHGYMAPEVLM---KGQAYDSSAD 9
>12786
          Length = 460

 Score = 52.8 bits (125), Expect = 6e-07,   Method: Compositional matrix adjust.
 Identities = 36/113 (31%), Positives = 53/113 (46%), Gaps = 23/113 (20%)
 Frame = -3

Query: 136 LQGLAYLHSHTMIHRDIKAGNILLTEPGQVKLADFGSASM------ASPANSFVGTPYWM 189
           L+ +  LH+  +IH D+K  N +L   G +KL DFG A+       +   +S VGTP +M
Sbjct: 380 LRAVKALHNEGVIHSDLKPANFMLVA-GNLKLIDFGIANTLQQDKTSVLKDSRVGTPSYM 204

Query: 190 APEVILAM------DEGQYDG-----------KVDVWSLGITCIELAERKPPL 225
           +PE I+A       D  + DG           + DVWSLG     +   + P 
Sbjct: 203 SPEAIMAACDDSADDSMEEDGHRTKPKYKVGVRSDVWSLGCILYNMVYGRTPF 45
>07940
          Length = 1336

 Score = 52.0 bits (123), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 35/104 (33%), Positives = 53/104 (50%), Gaps = 6/104 (5%)
 Frame = -3

Query: 121 KPLQEVEIAAITHGALQGLAYLHSHTMIHRDIKAGNILLTEPGQVKLADFGSASMASPAN 180
           K L   ++ +  +   +G+ YL S   IHRD+ A N+L+ E   +K+ADFG        +
Sbjct: 362 KMLTPKDLISYAYQVARGMEYLASKQCIHRDLAARNVLVAEEYVLKIADFGLTRNLQQFD 183

Query: 181 SFVGT-----PY-WMAPEVILAMDEGQYDGKVDVWSLGITCIEL 218
            +  T     P  WMAPE   A+ + +Y  K DVWS G+   E+
Sbjct: 182 YYRKTTDGRLPVKWMAPE---ALFDRKYTSKSDVWSYGVLLWEI 60
>17253
          Length = 483

 Score = 51.6 bits (122), Expect = 2e-06,   Method: Composition-based stats.
 Identities = 33/138 (23%), Positives = 72/138 (52%), Gaps = 15/138 (10%)
 Frame = -1

Query: 49  RTNEVVAIKKMSYSGKQSTEKWQDIIKEVKFLQRI-KHPNSIEYKGCYLREHTAWLVMEY 107
           R  + VA+K  + +   + +   + ++E+  ++++ +HPN + + GC      A ++ME+
Sbjct: 474 RQWDTVAVKTHNEAATDAEK--SEFLRELSIMRKLPRHPNVVSFMGCCTMSDPALILMEF 301

Query: 108 CLGSASDLLEVHKK--PLQEVEIAAITHG------------ALQGLAYLHSHTMIHRDIK 153
           C     DLL   +K  P + V + +  +               +G+A++ ++ ++HRD+ 
Sbjct: 300 C--CHGDLLSFLRKRRPDRTVFLTSTANDLTARDFFSFALHVARGMAHVANNKIVHRDVA 127

Query: 154 AGNILLTEPGQVKLADFG 171
           A N+L++E    K++DFG
Sbjct: 126 ARNVLISERNVCKVSDFG 73
>12672
          Length = 773

 Score = 50.4 bits (119), Expect = 3e-06,   Method: Composition-based stats.
 Identities = 31/98 (31%), Positives = 46/98 (46%), Gaps = 10/98 (10%)
 Frame = +3

Query: 131 ITHGALQGLAYLHSHTMIHRDIKAGNILLTEPGQVKLADF--------GSASMASPANSF 182
           I  G   G+ YL+ +  +HRDIK  NILL      K+ DF        G       A+  
Sbjct: 6   IVKGTASGIQYLNDNGHVHRDIKTANILLDSEYTAKVGDFATVVSAPSGEGKTVQNASVV 185

Query: 183 VGTPYWMAPEVILAMDEGQYD--GKVDVWSLGITCIEL 218
           +GT  ++APE I       +D   K+D +S G+  +E+
Sbjct: 186 IGTAAYLAPEAI------HFDVSTKLDSYSFGVVLLEV 281
>14477
          Length = 493

 Score = 50.4 bits (119), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 51/172 (29%), Positives = 85/172 (49%), Gaps = 4/172 (2%)
 Frame = -1

Query: 25  EKLFTDLREIGHGSFGAVY--FARDVRTNEVVAIKKMSYSGKQSTEKWQDIIKEVKFLQR 82
           E++  D  ++G G+FG+V     R       VAIK +  +    + +  ++IKE + +++
Sbjct: 493 EQIQMDELKLGAGNFGSVMKGVCRLDDREIPVAIKVLKNADLDPSVQ-SELIKEAEVMKK 317

Query: 83  IKHPNSIEYKGCYLREHTAWLVMEYC-LGSASDLLEVHKK-PLQEVEIAAITHGALQGLA 140
           + H + +   G    E T  LV+E   LG  +  L  +K  PL    I  +     QG+ 
Sbjct: 316 MDHMHIVRLIGLCEGE-TMMLVLELAKLGPLNKFLPKNKHLPLWN--ILELMWQVSQGME 146

Query: 141 YLHSHTMIHRDIKAGNILLTEPGQVKLADFGSASMASPANSFVGTPYWMAPE 192
           YL ++  +HRD+ A NILL +    K++DFG +   S  N+     Y+MA E
Sbjct: 145 YLEANKFVHRDLAARNILLCDEHFAKISDFGMSKTLSRENN-----YYMAQE 5
>18996
          Length = 491

 Score = 49.7 bits (117), Expect = 6e-06,   Method: Compositional matrix adjust.
 Identities = 42/156 (26%), Positives = 72/156 (46%), Gaps = 14/156 (8%)
 Frame = +2

Query: 148 IHRDIKAGNILLTEPGQVKLADFGSASMASPANSFVGT-----PY-WMAPEVILAMDEGQ 201
           IHRD+ A NIL+     VK++DFG A  A+    + G      P  W +PE   A++  +
Sbjct: 2   IHRDLAARNILVDR-SCVKISDFGLAQFANADGYYYGISQRDIPIKWYSPE---AIETCK 169

Query: 202 YDGKVDVWSLGITCIELAERKP-----PLFNMNAMSALYHIAQNE---SPTLQSNEWSDY 253
           +    DVWS G+T  E+  R       P  ++     L  + + E    P L S+     
Sbjct: 170 FSSYSDVWSYGVTLFEMFSRGEIPNLLPGHDLTQEEFLNRLRKGERLPKPELCSDF---V 340

Query: 254 FRNFVDSCLQKIPQDRPTSEELLKHMFVLRERPETV 289
           +   +  C  ++P+ RPT  ++++   + RE  + +
Sbjct: 341 YSELMRPCWHEMPKSRPTFHQIIQ--IIAREMGDNI 442
>02638
          Length = 1490

 Score = 49.3 bits (116), Expect = 7e-06,   Method: Composition-based stats.
 Identities = 30/100 (30%), Positives = 51/100 (51%), Gaps = 3/100 (3%)
 Frame = +1

Query: 182 FVGTPYWMAPEVILAMDEGQYDGKVDVWSLGITCIELAERKPPLFN---MNAMSALYHIA 238
            +GT  +MAPEV+     G+     DVWS+G   IE+   +PP  +    N ++ ++ IA
Sbjct: 16  LLGTIAFMAPEVLRGESYGR---ACDVWSVGCVMIEMCTCRPPWNSHDISNHLALIFKIA 186

Query: 239 QNESPTLQSNEWSDYFRNFVDSCLQKIPQDRPTSEELLKH 278
            +  P       S   R+ +  CL++    RP++++LL H
Sbjct: 187 SSVDPPPIPENMSPPVRDLMLRCLEQDSDFRPSAKDLLMH 306
>07836
          Length = 1478

 Score = 49.3 bits (116), Expect = 8e-06,   Method: Compositional matrix adjust.
 Identities = 40/129 (31%), Positives = 63/129 (48%), Gaps = 19/129 (14%)
 Frame = -1

Query: 110  GSASDLLEVHKKPLQEVEIAAITHGALQGLAYLHSHT--------MIHRDIKAGNILLTE 161
            GS  D L    + L   E+ A+ H A+ GLA+LH           + HRDIK+ NIL+ +
Sbjct: 1298 GSLHDYLL--SRVLDSSEMLALAHSAICGLAHLHIEIFGTRGKPAIAHRDIKSKNILVKK 1125

Query: 162  PGQVKLADFGSAS--------MASPANSFVGTPYWMAPEVI-LAMDEGQYDG--KVDVWS 210
             G   +AD G A         +    N   GT  +MAPEV+ + ++   +D   + D+++
Sbjct: 1124 NGTCCIADLGLAVRYISESNEVDVAPNPRQGTKRYMAPEVLEMLLNVKNFDAFKQADMYA 945

Query: 211  LGITCIELA 219
             G+   E+A
Sbjct: 944  FGLVMWEIA 918
>32359
          Length = 928

 Score = 48.9 bits (115), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 37/130 (28%), Positives = 69/130 (53%), Gaps = 9/130 (6%)
 Frame = -1

Query: 28  FTDLREIGHGSFGAVYFARDVRTNEVVAIKKMSYSGKQSTEKWQDIIKEVKFLQRIKHPN 87
           +TD + IG+GSFG VY A+ V T+E+VAIKK+        +++++  +E++ +++++H N
Sbjct: 424 YTDAKVIGNGSFGVVYQAKLVDTSELVAIKKV-----LQDKRFKN--RELQIMRKLEHQN 266

Query: 88  SIEYKGCYLR------EHTAWLVMEYCLGSASDLLEVHKKPLQEVEIAAI---THGALQG 138
            ++ K  +        E    LV+EY   +   +   + K  Q + I  I    +   + 
Sbjct: 265 IVKLKFFFYSSGEKKDEVFLNLVLEYVPETVYRVARHYSKSKQTIPILYIKLYMYQLFRS 86

Query: 139 LAYLHSHTMI 148
           LAY+HS   +
Sbjct: 85  LAYIHSQACV 56
>06358
          Length = 1517

 Score = 47.0 bits (110), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 45/145 (31%), Positives = 68/145 (46%), Gaps = 23/145 (15%)
 Frame = +3

Query: 109 LGSASDLLEVHKKPLQEVEI--AAITHGALQ---GLAYLHSHT-MIHRDIKAGNILLTEP 162
           LG  S +  V K+ LQ+ ++    I HG LQ    L +LH+   M+HR++    I+LT+ 
Sbjct: 297 LGDLSSIXTVPKE-LQDYQLYDVEIKHGLLQVTEALGFLHNDAKMMHRNVCPEAIMLTKL 473

Query: 163 GQVKLADFGSASMAS------PANSF---------VGTPY--WMAPEVILAMDEGQYDGK 205
           G  KLA +     +S      P+  F         V  P+  +MAPE +L M  G     
Sbjct: 474 GSWKLAGYEFCVRSSDPQSTDPSYPFYEWRSDIAPVTQPHLDFMAPEYVLTMQCGTGS-- 647

Query: 206 VDVWSLGITCIELAERKPPLFNMNA 230
            D++SLG+    +  +  PLF  N 
Sbjct: 648 -DMFSLGLLVYSVFAKGKPLFECNG 719
>17516
          Length = 453

 Score = 44.3 bits (103), Expect = 3e-04,   Method: Composition-based stats.
 Identities = 22/40 (55%), Positives = 27/40 (67%)
 Frame = -3

Query: 179 ANSFVGTPYWMAPEVILAMDEGQYDGKVDVWSLGITCIEL 218
           A +  GTP +MAPEV+L   +GQYD K DV+SL I   EL
Sbjct: 448 AGTLAGTPVYMAPEVLL--QKGQYDMKADVYSLAIILWEL 335
>25019
          Length = 730

 Score = 43.9 bits (102), Expect = 3e-04,   Method: Composition-based stats.
 Identities = 27/72 (37%), Positives = 38/72 (52%), Gaps = 4/72 (5%)
 Frame = +3

Query: 154 AGNILLTEPGQVKLADFGSASMA----SPANSFVGTPYWMAPEVILAMDEGQYDGKVDVW 209
           A N+LL + G VKL DFG    A       ++F GT  +MAPE++     G+    VD W
Sbjct: 258 AENVLLDKDGHVKLTDFGLCKEAITGTRVTHTFCGTIEYMAPEILTRTGHGK---AVDWW 428

Query: 210 SLGITCIELAER 221
           SLG + +   +R
Sbjct: 429 SLGSSYV*YVDR 464
>16708
          Length = 1397

 Score = 43.5 bits (101), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 43/163 (26%), Positives = 72/163 (44%), Gaps = 18/163 (11%)
 Frame = -1

Query: 31   LREIGHGSFGAVYFARDVRTNEVVAIKKMSYSGKQSTEKWQDIIKEVKFLQRIKHPNSIE 90
            L+ +G G FG VY AR + T+E  A+K        ++      + EV+ L RI+      
Sbjct: 1388 LQVLGKGVFGKVYEARLLSTHEKAALK--------TSILCHHSLDEVEALGRIE------ 1251

Query: 91   YKGCYLRE-HTAW-----------LVMEYCLGSASDLLEVHKK---PLQ---EVEIAAIT 132
              G YL +   AW           L+  Y +G   ++   +K    P++      +  I 
Sbjct: 1250 -GGFYLAQMFGAWVTCLPFPKMNILLHFYEMGPLCNVYAHYKNKEMPIRWSNPAMVCCIA 1074

Query: 133  HGALQGLAYLHSHTMIHRDIKAGNILLTEPGQVKLADFGSASM 175
               +  L ++H   ++H D+KA N+L+   G  KL D+G A +
Sbjct: 1073 GQXVCALEHIHELGVVHMDVKADNVLVDAHGNCKLTDYGIAQL 945
>11185
          Length = 473

 Score = 42.4 bits (98), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 43/171 (25%), Positives = 68/171 (39%), Gaps = 26/171 (15%)
 Frame = +1

Query: 136 LQGLAYLHSHTMIHRDIKAGNILLTEPGQVKLADFGSASM------------ASPANSF- 182
           + GL Y+HS  ++  D++   +LL   G +K ADFG + +            A   + + 
Sbjct: 31  VTGLHYIHSLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEAGDQWN 210

Query: 183 -------------VGTPYWMAPEVILAMDEGQYDGKVDVWSLGITCIELAERKPPLFNMN 229
                         G+P +MAPEV    +        D+W+LG    E+       F+ +
Sbjct: 211 IQSAEEMMKQVPTSGSPTYMAPEVFQGAEPSIMS---DLWALGCVFYEM-------FSGS 360

Query: 230 AMSALYHIAQNESPTLQSNEWSDYFRNFVDSCLQKIPQDRPTSEELLKHMF 280
            +SA        SP          F N ++S LQK    R +   L+KH F
Sbjct: 361 RLSA------KPSPE---------FLNLLESLLQKDSTRRLSWASLVKHAF 468
>17300
          Length = 480

 Score = 40.0 bits (92), Expect = 0.005,   Method: Composition-based stats.
 Identities = 29/89 (32%), Positives = 39/89 (43%), Gaps = 8/89 (8%)
 Frame = +1

Query: 138 GLAYLHSHTMIHRDIKAGNILLTEPGQVKLADFG-SASMASPANSFVGTP-------YWM 189
           G+  L     +HRD+ A NIL+ E    K+ADFG S  + S       T         W 
Sbjct: 10  GMGXLADMGYVHRDLAARNILVNEILVCKVADFGLSREIESDTTEGAYTTKGGKIPVRWT 189

Query: 190 APEVILAMDEGQYDGKVDVWSLGITCIEL 218
           APE I      ++    DVWS G+   E+
Sbjct: 190 APEAIAYR---KFTSASDVWSFGVVMWEV 267
>32691
          Length = 295

 Score = 40.0 bits (92), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 18/50 (36%), Positives = 30/50 (60%)
 Frame = +1

Query: 250 WSDYFRNFVDSCLQKIPQDRPTSEELLKHMFVLRERPETVLIDLIQRTKD 299
           WS  F +FV  CL K P++R T+ +LL+H F+ +     +L  +I+  K+
Sbjct: 85  WSTEFIDFVSKCLVKNPENRATAVDLLQHDFIKKAEACEILQAMIREAKE 234
>20640
          Length = 1492

 Score = 38.1 bits (87), Expect = 0.018,   Method: Composition-based stats.
 Identities = 23/77 (29%), Positives = 37/77 (48%), Gaps = 6/77 (7%)
 Frame = +1

Query: 148 IHRDIKAGNILLTEPGQVKLADFGSASMASPANSFVGTPY------WMAPEVILAMDEGQ 201
           +HRD+   N L+     VK++DFG A      + + G+ +      WM  E IL     +
Sbjct: 10  VHRDLATRNCLVGHDLVVKISDFGLARSVHSVDYYRGSEHDAIPIRWMPLEAILY---NK 180

Query: 202 YDGKVDVWSLGITCIEL 218
           +  + DVWS G+   E+
Sbjct: 181 FSTQSDVWSFGVVLWEI 231
>32000
          Length = 644

 Score = 37.7 bits (86), Expect = 0.020,   Method: Composition-based stats.
 Identities = 25/79 (31%), Positives = 41/79 (51%), Gaps = 4/79 (5%)
 Frame = -1

Query: 163 GQVKLADFGSASM-ASPANSF---VGTPYWMAPEVILAMDEGQYDGKVDVWSLGITCIEL 218
            ++K+ADFG A +   P  ++   V T ++ APE++L      Y   VD+WSLG   +E+
Sbjct: 578 AKMKIADFGLARVFGLPVRTYTHEVITLWYRAPEILLGCR--FYSVPVDIWSLGCIFVEM 405

Query: 219 AERKPPLFNMNAMSALYHI 237
             R+      + +  LY I
Sbjct: 404 MTRRALFPGDSEIDQLYRI 348
>31489
          Length = 329

 Score = 37.0 bits (84), Expect = 0.040,   Method: Composition-based stats.
 Identities = 28/93 (30%), Positives = 43/93 (46%), Gaps = 11/93 (11%)
 Frame = +3

Query: 77  VKFLQRIKHPNSIEYKGC---------YLREHTAWLVMEYCLGSASDLLEV--HKKPLQE 125
           +K L+  KH N I  +           +   H  + +ME      SDL  +    +PL E
Sbjct: 3   IKILKHFKHDNIISIREILKPKDSYHDFKDIHVVFDLME------SDLHRIIYSDQPLTE 164

Query: 126 VEIAAITHGALQGLAYLHSHTMIHRDIKAGNIL 158
             I    +  L+GL Y+HS  ++HRD+K  N+L
Sbjct: 165 EHIRYFLYQILRGLKYIHSANVVHRDLKPSNLL 263
>07833
          Length = 1504

 Score = 36.2 bits (82), Expect = 0.076,   Method: Compositional matrix adjust.
 Identities = 48/229 (20%), Positives = 84/229 (36%), Gaps = 23/229 (10%)
 Frame = -3

Query: 71   QDIIKEVKFLQRIKHPNSIEYKGCYLREHTAWLVMEYC-LGSASDLLEVHKKPL----QE 125
            +D ++E   L+   HPN +    C  +     L+ ++   GS  + L      +    Q 
Sbjct: 1484 RDFMEEFPRLRIFNHPNVLPVLACCNQPPNLVLISQFMPFGSLYNTLHGESGIVVDQNQS 1305

Query: 126  VEIAAITHGALQGLAYLHS-------------HTMIHRDIKAGNILLTEPGQVKLADFGS 172
            +  A       +G+ +LHS             H MI  D+ A         ++ +AD+  
Sbjct: 1304 LRFAM---DIARGMEFLHSMEPTIPNFLLTSKHVMIDEDLTA---------RINMADY-- 1167

Query: 173  ASMASPANSF-----VGTPYWMAPEVILAMDEGQYDGKVDVWSLGITCIELAERKPPLFN 227
                    SF     V +P WMAPE +    +       D+WS  I   EL  R+ P   
Sbjct: 1166 ------CFSFHEKGKVYSPAWMAPEALQRRPDDINTRAADMWSFAILMWELETREVPFAE 1005

Query: 228  MNAMSALYHIAQNESPTLQSNEWSDYFRNFVDSCLQKIPQDRPTSEELL 276
            +++M     +A            S +    +  C+ + P  RP  + ++
Sbjct: 1004 LSSMEVGMKVALEGLRISIPPGISLHMSRLIKICMNEEPGKRPRFDMII 858
>18663
          Length = 600

 Score = 35.8 bits (81), Expect = 0.083,   Method: Composition-based stats.
 Identities = 19/45 (42%), Positives = 27/45 (60%), Gaps = 1/45 (2%)
 Frame = +2

Query: 180 NSFVGTPYWMAPEVILAMDEGQYDGKVDVWSLGITCIE-LAERKP 223
           ++F GTP ++APE++   D   Y   VD W+LG+   E LA R P
Sbjct: 2   STFCGTPNYIAPEILRGED---YGFSVDWWALGVLLYEMLAGRSP 127
>29360
          Length = 363

 Score = 35.4 bits (80), Expect = 0.13,   Method: Compositional matrix adjust.
 Identities = 36/121 (29%), Positives = 55/121 (45%), Gaps = 10/121 (8%)
 Frame = +3

Query: 50  TNEVVAIKKM----SYSGKQSTEKWQDIIKEVKFLQRIKHPNSIEYKG-----CYLREHT 100
           T+E+VAIK +    SY+ +   E        V  LQR+   ++ +Y       C+  ++ 
Sbjct: 24  TSEIVAIKILKNHPSYARQGQIE--------VSILQRLSQESADDYNFVRAFECFQHKNH 179

Query: 101 AWLVMEYCLGSASDLLEVHK-KPLQEVEIAAITHGALQGLAYLHSHTMIHRDIKAGNILL 159
             LV E    +  D L+ +K +PL    I  IT   L  L  L    +IH D+K  NI+L
Sbjct: 180 TCLVFEMLEQNLYDFLKQNKFQPLPLKYIRPITQQVLTALRKLKQLGLIHADLKPENIML 359

Query: 160 T 160
            
Sbjct: 360 V 362
>00486
          Length = 797

 Score = 35.0 bits (79), Expect = 0.13,   Method: Composition-based stats.
 Identities = 26/92 (28%), Positives = 41/92 (44%), Gaps = 2/92 (2%)
 Frame = -2

Query: 180 NSFVGTPYWMAPEVILAMDEGQYDGKVDVWSLGITCIELAERKPPLFNMNAMSALYHIAQ 239
           ++F GT  +MAPE++     G+    VD WSLG    ++    PP    N    +  I +
Sbjct: 784 HTFCGTIEYMAPEILTRTGHGK---AVDWWSLGALMYDMLTGSPPFTAENRKKTIDKILK 614

Query: 240 NE--SPTLQSNEWSDYFRNFVDSCLQKIPQDR 269
            +   P   +NE     R  +   L+K P +R
Sbjct: 613 GKLNLPPYLTNE----ARGLIKKLLRKNPAER 530
>08294
          Length = 1849

 Score = 35.0 bits (79), Expect = 0.15,   Method: Compositional matrix adjust.
 Identities = 46/214 (21%), Positives = 81/214 (37%), Gaps = 24/214 (11%)
 Frame = +2

Query: 86   PNSIEYKGCYLREHTAWLVMEYC-------------------LGSASDLLEVHKKPLQEV 126
            PN + + G        +L+ EYC                    G+    L + +K     
Sbjct: 887  PNIVHFMGVCREAEPHFLITEYCDWGDLKQFLLATRNDNGRGRGTRVPALALSQKLGMGQ 1066

Query: 127  EIAAITHGALQGLAYLHSHTMIHRDIKAGNILLTEPGQVKLADFG-----SASMASPANS 181
            ++AA       G+  L +  ++H D+ A N+LLT   Q+K+A         AS   P + 
Sbjct: 1067 QVAA-------GMEALSNQGLVHGDLAARNVLLTSRMQLKVARPALSGDVYASEYYPLHQ 1225

Query: 182  FVGTPYWMAPEVILAMDEGQYDGKVDVWSLGITCIELAERKPPLFNMNAMSALYHIAQNE 241
             +    W+ PE +L  D     G  DVW+ G+   E+ +     + + +   +    Q+ 
Sbjct: 1226 RLVPLRWLPPEGVLE-DSATTCG--DVWAFGVFLWEVLQLADLPYRLMSDEEVLRSLQHS 1396

Query: 242  SPTLQSNEWSDYFRNFVDSCLQKIPQDRPTSEEL 275
               L S +      + +  C  + P  RP   E+
Sbjct: 1397 QAALDSPDAPPALLSLLQRCTAQQPSQRPPFSEI 1498
>37063
          Length = 455

 Score = 34.3 bits (77), Expect = 0.26,   Method: Composition-based stats.
 Identities = 26/76 (34%), Positives = 37/76 (48%), Gaps = 14/76 (18%)
 Frame = -2

Query: 152 IKAGNIL---LTEPGQVKLADF---------GSASMASPANSFVGTPYWMAPEVILAM-- 197
           +K  NIL   L E   +K+ DF         G  +      + VG+  +MAPEV+ A   
Sbjct: 454 LKPENILCEHLDEVVPLKICDFDLASGINCDGDGTKTPELLTPVGSAEYMAPEVVDAWVG 275

Query: 198 DEGQYDGKVDVWSLGI 213
           +   YD + D+WSLGI
Sbjct: 274 ESFSYDKRCDMWSLGI 227
>18481
          Length = 437

 Score = 33.5 bits (75), Expect = 0.44,   Method: Composition-based stats.
 Identities = 31/123 (25%), Positives = 50/123 (40%), Gaps = 4/123 (3%)
 Frame = -1

Query: 69  KWQDIIKEVKFLQRI-KHPNSIEYKGCYLREHTAWLVMEYCLGSASDLLEVHKKPLQEVE 127
           K Q +  E K  ++I +HP           +H   LVME    S  +L  + K+      
Sbjct: 371 KHQLLHYEAKVYEQIGRHPGLPTMYHYGTEKHFNALVMELLGPSLEELFVICKRRFTLKT 192

Query: 128 IAAITHGALQGLAYLHSHTMIHRDIKAGNILL---TEPGQVKLADFGSASMASPANSFVG 184
           I  ++   L  L ++H    IHRD+K  N L+       ++ + DFG +         + 
Sbjct: 191 ILMVSDQLLSRLEFIHQKCFIHRDLKPDNFLMGLGRHCHRLYIIDFGLSKRYKDTQGTMH 12

Query: 185 TPY 187
            PY
Sbjct: 11  IPY 3
>31789
          Length = 676

 Score = 33.1 bits (74), Expect = 0.53,   Method: Compositional matrix adjust.
 Identities = 27/87 (31%), Positives = 38/87 (43%), Gaps = 1/87 (1%)
 Frame = +2

Query: 14  EIAELFFKEDPEKLFTDLR-EIGHGSFGAVYFARDVRTNEVVAIKKMSYSGKQSTEKWQD 72
           EI E      P+  F     EIG GSF  VY   D      VA  ++       TE+ Q 
Sbjct: 281 EIEEKAVASSPDNRFLKFDVEIGRGSFKTVYKGLDTELGVAVAWCELQDKKWNKTER-QR 457

Query: 73  IIKEVKFLQRIKHPNSIEYKGCYLREH 99
             +E + L+ ++HPN + +   Y  EH
Sbjct: 458 FKEEAEMLKELQHPNIVRFFD-YWEEH 535
>22005
          Length = 873

 Score = 32.7 bits (73), Expect = 0.69,   Method: Composition-based stats.
 Identities = 24/87 (27%), Positives = 39/87 (44%), Gaps = 6/87 (6%)
 Frame = +1

Query: 138 GLAYLHSHTMIHRDIKAGNILLTEPGQVKLADFGSASMASPANSFVGTPY------WMAP 191
           G+AYL     +HRD+ A   + +      ++DFG A      + + G+        WM  
Sbjct: 478 GMAYLAQKDYVHRDL-ATRTVXSRTT*S*ISDFGLARSVHSVDYYRGSEQDAIPIRWMPL 654

Query: 192 EVILAMDEGQYDGKVDVWSLGITCIEL 218
           E IL     ++  + DVWS G+   E+
Sbjct: 655 EAILY---SKFSTQSDVWSFGVVLWEI 726
>20152
          Length = 445

 Score = 32.7 bits (73), Expect = 0.85,   Method: Composition-based stats.
 Identities = 35/120 (29%), Positives = 53/120 (44%), Gaps = 5/120 (4%)
 Frame = +1

Query: 191 PEVILAMDEGQYDG-KVDVWSLGITCIELAERKPPLFNMNAMSALYHI--AQNESPTLQS 247
           PE++L      YD   VDVWSLG+    L   + P    N    L  I   + + P   S
Sbjct: 1   PEILLG---DSYDAPAVDVWSLGVILYMLVVGEAPFQEANDSETLTMIMDCRYQIPPHIS 171

Query: 248 NEWSDYFRNFVDSCLQKIPQDRPTSEELLKHMFVLRE--RPETVLIDLIQRTKDAVRELD 305
           ++  D     ++  LQ+ P DR +   +L H ++      P T  + LI  TK+ + E D
Sbjct: 172 HKCQD----LIEKMLQREPVDRASLPHILAHPWLNDGDLTPTTAYLPLI--TKEMISEED 333
>30360
          Length = 333

 Score = 32.0 bits (71), Expect = 1.4,   Method: Composition-based stats.
 Identities = 15/53 (28%), Positives = 26/53 (49%)
 Frame = +2

Query: 53  VVAIKKMSYSGKQSTEKWQDIIKEVKFLQRIKHPNSIEYKGCYLREHTAWLVM 105
           ++++ ++SYS +Q    WQ +I    F  R     ++  K C+     AW VM
Sbjct: 110 LLSLGRLSYSFQQRLYNWQHVIYRFSFESRPHIIGNLRCKICFFGACLAWCVM 268
>26009
          Length = 886

 Score = 32.0 bits (71), Expect = 1.4,   Method: Composition-based stats.
 Identities = 15/51 (29%), Positives = 30/51 (58%)
 Frame = +3

Query: 127 EIAAITHGALQGLAYLHSHTMIHRDIKAGNILLTEPGQVKLADFGSASMAS 177
           E  ++    +  L ++HS  ++HRDIK  N+L+  P   +++ + SA +A+
Sbjct: 714 EAKSVMKQLVSALDFMHSKQLVHRDIKPENVLILTPDFSRVS*WTSA*LAN 866
>00394
          Length = 548

 Score = 31.2 bits (69), Expect = 1.9,   Method: Compositional matrix adjust.
 Identities = 23/77 (29%), Positives = 35/77 (45%), Gaps = 1/77 (1%)
 Frame = -2

Query: 24  PEKLFTDL-REIGHGSFGAVYFARDVRTNEVVAIKKMSYSGKQSTEKWQDIIKEVKFLQR 82
           P+  F    +EIG GSF  VY   D      VA  ++        E+ Q   +E + L+ 
Sbjct: 307 PDNRFLKFDKEIGRGSFKTVYKGLDTELGVAVAWCELQDKKWNKAER-QRFKEEAEMLKE 131

Query: 83  IKHPNSIEYKGCYLREH 99
           ++HPN + +   Y  EH
Sbjct: 130 LQHPNIVRFFD-YWEEH 83
>36481
          Length = 806

 Score = 31.2 bits (69), Expect = 2.0,   Method: Composition-based stats.
 Identities = 29/135 (21%), Positives = 63/135 (46%), Gaps = 8/135 (5%)
 Frame = +2

Query: 35  GHGSFGAVYFARDVRTNEVVAIKKMSYSGKQSTEKWQDIIK-EVKFLQRIKHPNSIEYKG 93
           G G+FG V   +D+   + +A+K +     ++ +K+++  K E+  L++++  +      
Sbjct: 389 GEGTFGKVVQCKDLLKGDDIALKII-----KNVDKYREAAKLEINVLEKLREKDPHAKHM 553

Query: 94  C-----YLREHTAWLVMEYCLG-SASDLLEVHKKPLQEVE-IAAITHGALQGLAYLHSHT 146
           C     +   H    +  + LG S  D L+ +      +E +  I++     + +LH + 
Sbjct: 554 CVQMLDWFDYHGHVCISFHMLGLSVFDFLKDNSYGAYPIEQVRHISYQLCYAVNFLHENQ 733

Query: 147 MIHRDIKAGNILLTE 161
           + H D+K  NIL  +
Sbjct: 734 LTHTDLKPENILFVD 778
>32957
          Length = 645

 Score = 30.8 bits (68), Expect = 2.7,   Method: Composition-based stats.
 Identities = 17/38 (44%), Positives = 22/38 (57%)
 Frame = +3

Query: 181 SFVGTPYWMAPEVILAMDEGQYDGKVDVWSLGITCIEL 218
           +F GT  +MAPEV    +  +Y  +VD W LGI   EL
Sbjct: 42  TFCGTREYMAPEV---HERKEYGKEVDWWGLGILLHEL 146
>11516
          Length = 1175

 Score = 30.4 bits (67), Expect = 3.3,   Method: Compositional matrix adjust.
 Identities = 35/141 (24%), Positives = 59/141 (41%), Gaps = 8/141 (5%)
 Frame = +3

Query: 47  DVRTNEVVAIKKMSYSGKQSTEKW-QDIIKEVKFLQRIKHPNSIEYKG-C-----YLREH 99
           D+   +V A      S ++   +  Q I+KE+  LQ + H N ++  G C     Y  E 
Sbjct: 597 DIGGQDVTACMDTGRSLRECYHRAAQKIVKEIVLLQALAHDNVVQVLGFCVPDKAYDGEG 776

Query: 100 TAWLVMEYCLGSASDLLE-VHKKPLQEVEIAAITHGALQGLAYLHSHTMIHRDIKAGNIL 158
              +VM   LG   DL++ +H      + I+      L  L+      ++  D +    +
Sbjct: 777 DTTVVMVTELGEPIDLIKLLHMSWEDRLRISYDLTKLLHFLSQSARGALVMNDFRRQQFV 956

Query: 159 LTEPGQVKLADFGSASMASPA 179
           L + G +KL+D   A    PA
Sbjct: 957 LVD-GALKLSDVDDAGFDEPA 1016
>29011
          Length = 374

 Score = 28.9 bits (63), Expect = 9.5,   Method: Composition-based stats.
 Identities = 18/51 (35%), Positives = 27/51 (52%)
 Frame = +2

Query: 254 FRNFVDSCLQKIPQDRPTSEELLKHMFVLRERPETVLIDLIQRTKDAVREL 304
           F+ F+D CLQ   + R ++ +LL H F+ +      L  LI+  K   REL
Sbjct: 92  FKTFLDKCLQVEVESRSSAVDLLTHPFLTKALELRTLGPLIRAAK---REL 235
>07687
          Length = 1774

 Score = 28.9 bits (63), Expect = 9.5,   Method: Composition-based stats.
 Identities = 19/54 (35%), Positives = 26/54 (48%), Gaps = 6/54 (11%)
 Frame = +3

Query: 735 RQYKALRNHLLETTPKSE------HKAVLKRLKEEQTRKLAILAEQYDHSINEM 782
           R Y  L  HL  TTP S       HK ++ +   E  RK+ I   +YD +I +M
Sbjct: 3   RFYYDLFRHLFTTTPMSTK*ENIIHKTIISQQI*EAKRKMCIYKFKYDKTIPQM 164
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|158508501|ref|NP_998779.2| septin 5 [Mus musculus]
         (369 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

14132                                                                 174   5e-44
34156                                                                 119   2e-27
22078                                                                 102   2e-22
14677                                                                  89   5e-21
29788                                                                  81   8e-16
03856                                                                  28   6.8  
29907                                                                  27   9.0  
>14132
          Length = 422

 Score =  174 bits (441), Expect = 5e-44,   Method: Compositional matrix adjust.
 Identities = 80/141 (56%), Positives = 104/141 (73%)
 Frame = -2

Query: 112 FGDAVNNSECWKPITDYVDQQFEQYFRDESGLNRKNIQDNRVHCCLYFISPFGHGLRPVD 171
           FGDAV+NS CW+PITDY+D ++E+Y   ES +NR  + D RVHCCLYFI+P GHGL+P+D
Sbjct: 421 FGDAVDNSNCWQPITDYIDSKYEEYLNAESRVNRTVMPDTRVHCCLYFIAPTGHGLKPLD 242

Query: 172 VGFMKALHEKVNIVPLIAKADCLVPSEIRKLKDRIREEIDKFGIHVYQFPECDSDEDEDF 231
           V FMK LH+KVNI+PL+AKAD L P E R+ K  I  EI +  I +Y+FP+CD DE+E  
Sbjct: 241 VEFMKRLHDKVNIIPLVAKADTLTPDECREFKKTILNEIAQHKIKIYEFPDCD-DEEEMK 65

Query: 232 KQQDRELKESAPFAVIGSNTV 252
            Q+   + +  PFAV+GSN V
Sbjct: 64  IQKRLRVSDRVPFAVVGSNRV 2
>34156
          Length = 348

 Score =  119 bits (297), Expect = 2e-27,   Method: Compositional matrix adjust.
 Identities = 59/79 (74%), Positives = 69/79 (87%)
 Frame = -1

Query: 31  PNQVHRKSVKKGFDFTLMVAGESGLGKSTLVHSLFLTDLYKDRKLLSAEERINQTVEILK 90
           P QVHRKSVKKGF+FTLMV GESGLGKSTLV+SLFLTDLY +R + SA E+I QTV+I  
Sbjct: 237 PTQVHRKSVKKGFEFTLMVVGESGLGKSTLVNSLFLTDLYPERHIPSASEKIQQTVKIDA 58

Query: 91  HTVDIEEKGVKLKLTIVDT 109
            TV+IEE+GVKL+LT+VDT
Sbjct: 57  STVEIEERGVKLRLTVVDT 1
>22078
          Length = 417

 Score =  102 bits (255), Expect = 2e-22,   Method: Compositional matrix adjust.
 Identities = 52/101 (51%), Positives = 66/101 (65%), Gaps = 7/101 (6%)
 Frame = +3

Query: 261 RGRLYPWGIVEVENQAHCDFVKLRNMLIRTHMHDLKDVTCDVHYENYRAHCIQQM----- 315
           RGR YPWGIVEV+N +HCDF++LR MLI THM DLKDVT DVHYEN+R+  IQQ      
Sbjct: 3   RGRAYPWGIVEVDNXSHCDFIRLRQMLISTHMQDLKDVTSDVHYENFRSSFIQQSLAAQH 182

Query: 316 --TSKLTQDSRMESPIPILPLPTPDAETEKLIRMKDEELRR 354
              SKL +DS+        P      +T+ L++ KD E++R
Sbjct: 183 RERSKLKRDSK--------PCEEDGMDTDTLLQQKDAEIQR 281
>14677
          Length = 378

 Score = 89.4 bits (220), Expect(2) = 5e-21,   Method: Compositional matrix adjust.
 Identities = 39/76 (51%), Positives = 53/76 (69%), Gaps = 2/76 (2%)
 Frame = -1

Query: 86  VEILKHTVDIEEKGVKLKLTIVDTPGFGDAVNNSECWKPITDYVDQQFEQYFRDESGLNR 145
           V++  HT D+ EK V+LKLT VDT GFGD +N ++ WKPI DY+D QF+ Y ++E  + R
Sbjct: 228 VKLKAHTYDLTEKNVRLKLTTVDTTGFGDQINKADSWKPIVDYIDAQFDAYLQEELKIKR 49

Query: 146 --KNIQDNRVHCCLYF 159
              +  D+RVH CLYF
Sbjct: 48  MLHSYHDSRVHACLYF 1

 Score = 29.3 bits (64), Expect(2) = 5e-21,   Method: Compositional matrix adjust.
 Identities = 13/24 (54%), Positives = 18/24 (75%)
 Frame = -3

Query: 46  TLMVAGESGLGKSTLVHSLFLTDL 69
           T  V GE+G+GKSTL+ +LF T+ 
Sbjct: 334 TFFVLGETGIGKSTLMDTLFNTNF 263
>29788
          Length = 687

 Score = 80.9 bits (198), Expect = 8e-16,   Method: Compositional matrix adjust.
 Identities = 34/43 (79%), Positives = 37/43 (86%)
 Frame = +3

Query: 266 PWGIVEVENQAHCDFVKLRNMLIRTHMHDLKDVTCDVHYENYR 308
           PWGIVEVEN  H DF+ LRNMLIRTHM DLKDVT +VHYEN+R
Sbjct: 3   PWGIVEVENLEHNDFIALRNMLIRTHMQDLKDVTNNVHYENFR 131
>03856
          Length = 1292

 Score = 27.7 bits (60), Expect = 6.8,   Method: Compositional matrix adjust.
 Identities = 15/52 (28%), Positives = 20/52 (38%)
 Frame = -3

Query: 261  RGRLYPWGIVEVENQAHCDFVKLRNMLIRTHMHDLKDVTCDVHYENYRAHCI 312
            RG+  P G +      HCDF+     L++     L     DV  E  R  C 
Sbjct: 1074 RGKGIPNGQIVFHPYGHCDFLCFGKQLVKFLFFQLTTKPSDVKSERIRISCF 919
>29907
          Length = 1375

 Score = 27.3 bits (59), Expect = 9.0,   Method: Compositional matrix adjust.
 Identities = 9/22 (40%), Positives = 17/22 (77%)
 Frame = +1

Query: 281 VKLRNMLIRTHMHDLKDVTCDV 302
           +K+ N+L+ THM+D+ +  CD+
Sbjct: 550 IKVYNVLLITHMYDMWNTPCDI 615
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31980942|ref|NP_061352.2| inositol (myo)-1(or
4)-monophosphatase 1 [Mus musculus]
         (277 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

19070                                                                 144   5e-44
26940                                                                  86   3e-19
31082                                                                  57   7e-09
18168                                                                  36   0.016
>19070
          Length = 1247

 Score =  144 bits (364), Expect(2) = 5e-44,   Method: Compositional matrix adjust.
 Identities = 79/191 (41%), Positives = 112/191 (58%)
 Frame = +2

Query: 84  QPTWVIDPIDGTTNFVHRFPFVAVSIGFLVNKEMEFGIVYSCVEDKMYTGRKGKGAFCNG 143
           QP  +I  +     ++    FV+  +     KE   G++Y  V D MYT +KG+GAF NG
Sbjct: 389 QPGLLIQLMAPLILYIAFLKFVS-HLASQSTKEPLIGVIYLPVLDLMYTAQKGQGAFLNG 565

Query: 144 QKLQVSQQEDITKSLLVTELGSSRKPETLRIVLSNMEKLCSIPIHGIRSVGTAAVNMCLV 203
           +KL  S Q  + KS+++ E GSSR PE ++    NM +L +   HGIR  G+AA N+C V
Sbjct: 566 EKLSCSTQTSLNKSVVICEGGSSRGPEVVKRKSENMLQLVT-ATHGIRCYGSAAYNLCRV 742

Query: 204 ATGGADAYYEMGIHCWDMAGAGIIVTEAGGVLMDVTGGPFDLMSRRIIAANSITLAKRIA 263
           A G  DAY E GIH WD     +I  EAG V++D TG   DLMSRRI+AA++  LA +++
Sbjct: 743 AQGSGDAYVEYGIHIWDFVAGMLIAQEAGAVVLDPTGSEVDLMSRRILAASTPALASQLS 922

Query: 264 KEIEIIPLQRD 274
             +  + + RD
Sbjct: 923 SLLTHLDMGRD 955

 Score = 50.8 bits (120), Expect(2) = 5e-44,   Method: Compositional matrix adjust.
 Identities = 27/50 (54%), Positives = 34/50 (68%)
 Frame = +3

Query: 6   QECMDYAVILARQAGEMIREALKNEMDVMIKSSPADLVTVTDQKVEKMLM 55
           +E    AV +A++AGEMIR+A K E  V  KS  ADLVT TDQ VEK ++
Sbjct: 147 KEYFTVAVDVAKKAGEMIRDAFKKEKTVDTKSCAADLVTATDQAVEKNVL 296

 Score = 80.9 bits (198), Expect = 5e-16,   Method: Compositional matrix adjust.
 Identities = 46/104 (44%), Positives = 62/104 (59%), Gaps = 4/104 (3%)
 Frame = +1

Query: 52  KMLMSSIKEKYPCHSFIGEESVA-AGEKTVFTEQPTWVIDPIDGTTNFVHRFPFVAVSIG 110
           KM  S I+EKYP H FIGEE+ A  G +   T+ PTW+IDP+DGTTNFVH  P V  S+G
Sbjct: 286 KMSFSFIREKYPDHKFIGEETTAETGAQLELTDDPTWIIDPVDGTTNFVHSIPEVCFSLG 465

Query: 111 FLVN-KEMEFGIVYSCVEDKMYTGRKGKGAFCNGQK--LQVSQQ 151
             VN +  ++  + +C    ++ G KG G+     K  LQ S +
Sbjct: 466 VTVNXRASDWCYLPACPRPHVH-GTKGTGSIPQWGKVILQYSDK 594
>26940
          Length = 387

 Score = 85.9 bits (211), Expect(2) = 3e-19,   Method: Compositional matrix adjust.
 Identities = 38/84 (45%), Positives = 54/84 (64%), Gaps = 2/84 (2%)
 Frame = +2

Query: 41  DLVTVTDQKVEKMLMSSIKEKYPCHSFIGEESVAAGEKTV--FTEQPTWVIDPIDGTTNF 98
           ++VT  D ++E+ LM +I E YP H FIGEE            T+ PTW+IDPIDGT+NF
Sbjct: 62  NVVTEYDNQIEEFLMENILESYPDHKFIGEEDTHKNNNITKELTDAPTWIIDPIDGTSNF 241

Query: 99  VHRFPFVAVSIGFLVNKEMEFGIV 122
           + + P V+VSIG  +NKE+   ++
Sbjct: 242 IKQIPHVSVSIGLAINKEIVLAVI 313

 Score = 26.6 bits (57), Expect(2) = 3e-19,   Method: Compositional matrix adjust.
 Identities = 9/16 (56%), Positives = 13/16 (81%)
 Frame = +1

Query: 127 EDKMYTGRKGKGAFCN 142
           + K+YT + G+GAFCN
Sbjct: 325 QGKLYTAKLGQGAFCN 372
>31082
          Length = 339

 Score = 57.0 bits (136), Expect = 7e-09,   Method: Compositional matrix adjust.
 Identities = 28/78 (35%), Positives = 45/78 (57%), Gaps = 2/78 (2%)
 Frame = +3

Query: 187 IHGIRSVGTAAV--NMCLVATGGADAYYEMGIHCWDMAGAGIIVTEAGGVLMDVTGGPFD 244
           +H  R +  + V   +C+VA G  DA+Y   ++ WD A   ++V+EAGG++    GGPFD
Sbjct: 3   LHARRLLAYSCVVDELCMVAAGNLDAFYIEDMYPWDCAAGSLLVSEAGGIVTHPFGGPFD 182

Query: 245 LMSRRIIAANSITLAKRI 262
           +M   +I A +  L K +
Sbjct: 183 IMKPDLICAGTEELRKEL 236
>18168
          Length = 416

 Score = 36.2 bits (82), Expect = 0.016,   Method: Compositional matrix adjust.
 Identities = 17/33 (51%), Positives = 25/33 (75%)
 Frame = -3

Query: 245 LMSRRIIAANSITLAKRIAKEIEIIPLQRDDES 277
           LMS R+IAA ++ LA+ IA+E++ I   RDDE+
Sbjct: 414 LMSCRVIAAGTMELAQSIAQELQTIDYGRDDEN 316
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|21312654|ref|NP_083085.1| actin related protein 2/3
complex, subunit 5-like [Mus musculus]
         (153 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

10942                                                                 171   8e-44
37030                                                                  27   2.4  
>10942
          Length = 977

 Score =  171 bits (434), Expect = 8e-44,   Method: Compositional matrix adjust.
 Identities = 83/153 (54%), Positives = 108/153 (70%)
 Frame = +1

Query: 1   MARNTLSSRFRRVDIDEFDENKFVDEHXXXXXXXXXXXXDPCEVDGLLRQGDMLRAFHAA 60
           MA+NT +SRFR+VD+D++D++KFVD+             D  EV+  L QG    A    
Sbjct: 49  MAKNTGASRFRKVDVDQYDDDKFVDDSEIDADSDSQGIND-AEVNNFLAQGKHQDALKLV 225

Query: 61  LRNSPINTKNQAVKERAQGVVLKVLTNFKSSEIEQAVQSLDRNGIDLLMKYIYKGFEKPT 120
           L ++P+N+KNQAVK+RA   V++VLT+FKS +IE+AV+SLD   +D LMKYIY+GFE P 
Sbjct: 226 LNSAPVNSKNQAVKDRAASTVVRVLTSFKSVDIEKAVKSLDSKAVDTLMKYIYRGFESPA 405

Query: 121 ENSSAVLLQWHEKALAVGGLGSIIRVLTARKTV 153
           + SSAVLL WHEK  A GGLGSI+RVLT RK V
Sbjct: 406 DGSSAVLLTWHEKTFAAGGLGSIVRVLTDRKRV 504
>37030
          Length = 724

 Score = 27.3 bits (59), Expect = 2.4,   Method: Compositional matrix adjust.
 Identities = 22/61 (36%), Positives = 30/61 (49%), Gaps = 4/61 (6%)
 Frame = +3

Query: 73  VKERAQGVVLKVL----TNFKSSEIEQAVQSLDRNGIDLLMKYIYKGFEKPTENSSAVLL 128
           VKER +GVVLK+     T  +  +I QA   + R G  L  K   K  +  +EN  A L 
Sbjct: 414 VKERWRGVVLKLALFYSTQKRKDQIYQAGMGIVRPGAYLCPKDFGKAPQSLSENVRASLF 593

Query: 129 Q 129
           +
Sbjct: 594 R 596
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|111494223|ref|NP_780540.2| 5'-nucleotidase domain
containing 3 [Mus musculus]
         (546 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

37567                                                                 174   1e-43
13144                                                                  72   8e-13
20143                                                                  57   2e-08
26278                                                                  34   0.17 
17840                                                                  29   5.5  
04140                                                                  28   9.6  
>37567
          Length = 545

 Score =  174 bits (440), Expect = 1e-43,   Method: Compositional matrix adjust.
 Identities = 79/185 (42%), Positives = 130/185 (70%)
 Frame = +2

Query: 78  LNPDAIFSNNEMSLSDIEIYGFDYDYTLVFYSKHLHTLIFNAARDLLINEHRYPVEIRKY 137
           + PDAI++NNEMS       GFDYDYTL  Y+  LH LIF+  +  L+N  +YP EI  +
Sbjct: 2   MQPDAIYANNEMSNVAH*GVGFDYDYTLATYTPALHELIFDLGKQALVNNIKYPPEILDF 181

Query: 138 EYDPSFAIRGLHYDVQRAVLMKIDAFHYIQMGTVYRGLSVVPDEEVIDMYEGSHVPLEQM 197
           +YBP+FA+RGLH+D Q+ +LMKID+FH IQ+GTVYRG   V  EEV  +Y G+H+ L+ M
Sbjct: 182 KYBPNFAVRGLHFDTQKGLLMKIDSFHNIQLGTVYRGKQPVEPEEVKALYGGTHISLDYM 361

Query: 198 SDFYGKSSHGNTMKQFMDIFSLPEMTLLSCVNEHFLKNNIDYEPVHLYKDVKDSIRDVHI 257
           + +YG       M Q +D+F++PE++L++ + E+F ++++ Y+P +++ D++++++ +H 
Sbjct: 362 NTYYGTGP----MHQMIDLFAIPEISLIAHITEYFNQHSLVYDPEYVFYDIRNAVQGIHN 529

Query: 258 KGIMY 262
            G+++
Sbjct: 530 SGLLH 544
>13144
          Length = 457

 Score = 71.6 bits (174), Expect = 8e-13,   Method: Compositional matrix adjust.
 Identities = 48/145 (33%), Positives = 77/145 (53%), Gaps = 13/145 (8%)
 Frame = -2

Query: 262 YRAIEADIEKYICYAD-QTRAVLAKLAAHGKKMFLITNSPSSFVDKGMRYIVGKDWRDLF 320
           ++A+ AD ++Y+  +  +    L +L A GKK+FL+T S   F +      +G DWR  F
Sbjct: 429 FKAMRADPQRYVLPSSVKLLEWLQQLRAMGKKLFLLTGSNIDFANLTATQAMGADWRQQF 250

Query: 321 DVVIVQAEKPNFFNDKRRPFRKVNEKGV--LLWDKIH---KLQKGQIYKQGNLYEFLKLT 375
           D ++  A+KP FF   +RPF +V+E     L   +I     L  G +Y QGN ++ L LT
Sbjct: 249 DFIVTYAKKPGFFT-LQRPFMRVDENAQKELAGSEISLQADLHSGDVYSQGN-WQQLHLT 76

Query: 376 GWR-------GSKVLYFGDHIYSDL 393
             +        ++ LYFGD++  D+
Sbjct: 75  MAKLLNKDASAARALYFGDNLIQDI 1
>20143
          Length = 404

 Score = 57.0 bits (136), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 40/138 (28%), Positives = 62/138 (44%), Gaps = 3/138 (2%)
 Frame = +2

Query: 361 QIYKQGNLYEFLKLTGWRGSKVLYFGDHIYSDLADLTLKHGWRTGAIIPELRSELRIMNT 420
           Q+Y  G+   F K    +G  VLY GDHI+ D+       GWRT  I+PEL  EL +   
Sbjct: 2   QVYSGGSCELFTKFINAKGKDVLYVGDHIFGDILKSKKIRGWRTFLIVPELVRELHVWTD 181

Query: 421 EQYIQTMTWLQTLTGLLEQMQVHRDAESQLVLQEWXXXXXXXXXXTKSFFNAQF---GSL 477
           +   Q    LQ L   ++   ++RD +S   ++                 +  +   GSL
Sbjct: 182 K--CQLFAELQNLD--IKLGDLYRDLDSSAKVKPDISQLRTCIRDVTHKMDMSYGMMGSL 349

Query: 478 FRTDQNPTYFLRRLSRFA 495
           FR+    T+F  ++ R+A
Sbjct: 350 FRSGSRQTFFSSQVVRYA 403
>26278
          Length = 407

 Score = 33.9 bits (76), Expect = 0.17,   Method: Composition-based stats.
 Identities = 24/75 (32%), Positives = 36/75 (48%), Gaps = 11/75 (14%)
 Frame = +3

Query: 471 NAQFGSLFRTDQNPTYFLRRLSRFADIYMASLSCLLNYDVHHTFYPRRTP---------- 520
           +A F +   +   PT FL    R++ ++ A+ +CL      +T+YPRRTP          
Sbjct: 21  SASFLASTSSMMTPTRFL*H--RYSMLWQAAHTCL------YTWYPRRTPAASRALNMPL 176

Query: 521 -LQHELPAWSDSPSA 534
            LQ  L  W  +PSA
Sbjct: 177 *LQGSLGGWISTPSA 221
>17840
          Length = 437

 Score = 28.9 bits (63), Expect = 5.5,   Method: Composition-based stats.
 Identities = 17/52 (32%), Positives = 28/52 (53%), Gaps = 3/52 (5%)
 Frame = -3

Query: 228 VNEHFLKNNIDYEPVHLYKDVKDSIRDVH---IKGIMYRAIEADIEKYICYA 276
           +++H L  ++D E V L  DVK   RD+H   +  + Y A++ D+     YA
Sbjct: 249 MDKHVLVLSLDQE-VALTSDVKSEARDIHRVFVTNLTYHAVDQDVRACATYA 97
>04140
          Length = 1869

 Score = 28.1 bits (61), Expect = 9.6,   Method: Compositional matrix adjust.
 Identities = 13/39 (33%), Positives = 20/39 (51%)
 Frame = +1

Query: 333 FNDKRRPFRKVNEKGVLLWDKIHKLQKGQIYKQGNLYEF 371
           F   +RPFR++N    ++W K + + K      G  YEF
Sbjct: 694 FQPPKRPFRRMNYTDAIVWLKENNITK----DDGTFYEF 798
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|162287100|ref|NP_660125.2| membrane protein,
palmitoylated 4 [Mus musculus]
         (635 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

13641                                                                 173   1e-43
35802                                                                 129   3e-30
27435                                                                 125   4e-29
11512                                                                 113   2e-25
29974                                                                  80   3e-15
29636                                                                  72   6e-13
33158                                                                  72   9e-13
08480                                                                  67   2e-11
37412                                                                  55   7e-08
20073                                                                  48   1e-05
11574                                                                  38   0.012
26154                                                                  35   0.13 
30740                                                                  35   0.13 
33804                                                                  32   0.77 
03831                                                                  31   1.6  
09372                                                                  30   3.2  
23910                                                                  30   3.8  
17286                                                                  29   6.7  
>13641
          Length = 2081

 Score =  173 bits (439), Expect = 1e-43,   Method: Compositional matrix adjust.
 Identities = 90/207 (43%), Positives = 129/207 (62%), Gaps = 2/207 (0%)
 Frame = +2

Query: 412 YEEVVRYQRQPADKH-RLIVLVGPSGVGVNELRRQLIGCNPSCFQSAVPHTTRFPKSYEM 470
           Y+EV  +  +P  +H R IVL+G  G+G NEL+R+L   NP  F   VP+TTR  K +E 
Sbjct: 521 YDEVEHFTPKP--RHFRPIVLIGAPGIGRNELKRRLKASNPMHFLEVVPYTTRTKKPFEE 694

Query: 471 DGREYHYVSRETFESLMYGHKMLEYGEYKGHLYGTSVNAVHAVLDEGKICIMDLEPQDIQ 530
           DG+EYH+VSRE  E  +   K +EYGE+ GHLYGTSV ++  V+  GK+C++    Q ++
Sbjct: 695 DGKEYHFVSREDMEESIIAQKFVEYGEHHGHLYGTSVESIKQVIAAGKVCLLTPHTQALK 874

Query: 531 SARTRDLKPYVIFIKPPNTSSMRHSRKNAKITTDYYVDMK-FKDEDLQEMEELAQKMESQ 589
             RT +LKPYVIFIK P    ++ SR  A+        ++ F  E+L+EM E ++++E +
Sbjct: 875 FLRTYELKPYVIFIKSPTLEKLKESRMPARARATEADSIRPFSIEELEEMAETSRRLEER 1054

Query: 590 FGQFFDHVIVNDNLQDACGQLLSAIQK 616
           +G  FD  IVND+L DA  +LL    K
Sbjct: 1055YGHVFDITIVNDSLTDATTELLMVASK 1135

 Score = 89.4 bits (220), Expect = 4e-18,   Method: Compositional matrix adjust.
 Identities = 39/98 (39%), Positives = 61/98 (62%)
 Frame = +2

Query: 214 QVIHILAMSCGTIMFKVIPVSAPPVSSQKMVYVRAMIDYWPQEDPDIPCMDAGLPFLKGD 273
             + + + + G++  K++P    P S ++ + V+AM  +  + D +IPC +AGL F +GD
Sbjct: 62  NAVFVQSKTSGSLTLKLVPSRRTPGSKKREMVVKAMFSFNSKLDDNIPCKEAGLSFQQGD 241

Query: 274 ILQIVDQNDALWWQARKISDLTICAGLIPSNHLLKRKQ 311
           IL IV+Q DA+WWQA K  D    AGLIPS H  +R++
Sbjct: 242 ILHIVNQEDAIWWQAYKHGDAKKRAGLIPSRHYHERQE 355
>35802
          Length = 571

 Score =  129 bits (325), Expect = 3e-30,   Method: Compositional matrix adjust.
 Identities = 63/166 (37%), Positives = 101/166 (60%), Gaps = 1/166 (0%)
 Frame = +1

Query: 469 EMDGREYHYVSRETFESLMYGHKMLEYGEYKGHLYGTSVNAVHAVLDEGKICIMDLEPQD 528
           EM GR+YH+ SR  FE+ M   K LEYGE++ +LYGTSV AV  V+ +G++C+++LEP+ 
Sbjct: 1   EMTGRDYHFTSRSMFEADMLSGKFLEYGEFQSNLYGTSVEAVRQVILQGRVCLLNLEPES 180

Query: 529 IQSARTRDLKPYVIFIKPPNTSSMRHSR-KNAKITTDYYVDMKFKDEDLQEMEELAQKME 587
           ++  R  DLKPY  F+ PPN   +R       KI        +  D+ L+ + +  ++ME
Sbjct: 181 LKILRETDLKPYTXFVCPPNMEKLRQLHIAMGKI--------RPTDDQLKTVMDKGREME 336

Query: 588 SQFGQFFDHVIVNDNLQDACGQLLSAIQKAQEELQWVPEAWVSPDT 633
             +G FFD+ +VN ++  +  +L++ I + + E QWVP  W++  T
Sbjct: 337 DMYGHFFDYKLVNMDVDRSVQELMAEINRIEVEPQWVPVTWMNSFT 474
>27435
          Length = 456

 Score =  125 bits (315), Expect = 4e-29,   Method: Compositional matrix adjust.
 Identities = 58/157 (36%), Positives = 98/157 (62%)
 Frame = +1

Query: 469 EMDGREYHYVSRETFESLMYGHKMLEYGEYKGHLYGTSVNAVHAVLDEGKICIMDLEPQD 528
           E +G++YH+++R  FE+ M   K +EYGE++G+LYGT+V AV  V+ +G+ICI++L P+ 
Sbjct: 1   EHNGKDYHFITRAVFEADMLSGKFVEYGEFQGNLYGTTVEAVRQVIQQGRICILNLGPES 180

Query: 529 IQSARTRDLKPYVIFIKPPNTSSMRHSRKNAKITTDYYVDMKFKDEDLQEMEELAQKMES 588
           +++ R  +LKPY+IFI PP    +R  +             +  D+ ++E+ E  ++ME 
Sbjct: 181 LKNLRETELKPYIIFISPPXMEKLRQLQMALG-------KPRPTDDQVKEVIERGREMEE 339

Query: 589 QFGQFFDHVIVNDNLQDACGQLLSAIQKAQEELQWVP 625
            +  +FD+++VN  L  A  +LL  I + + E QWVP
Sbjct: 340 MYSHYFDYILVNMELNRAFDELLQEINRIETEPQWVP 450
>11512
          Length = 1006

 Score =  113 bits (282), Expect = 2e-25,   Method: Compositional matrix adjust.
 Identities = 57/157 (36%), Positives = 91/157 (57%), Gaps = 2/157 (1%)
 Frame = -3

Query: 475  YHYVSRETFESLMYGHKMLEYGEYKGHLYGTSVNAVHAVLDEGKICIMDLEPQDIQSART 534
            Y +V+RE  ++ +   K +E+GEYKGHLYGTS  +V ++++ G +C++    Q I++ RT
Sbjct: 1004 YIFVAREKMDADIEAGKFVEHGEYKGHLYGTSAESVKSIVNAGCVCVLSPHYQAIKTLRT 825

Query: 535  RDLKPYVIFIKPPNTSSMRHSRKN--AKITTDYYVDMKFKDEDLQEMEELAQKMESQFGQ 592
              LKP++I IKPP    ++ +R    AK T D      F DE+ ++M +   +++  +G 
Sbjct: 824  XQLKPFLIHIKPPELDILKSTRTEARAKSTFDEANARSFTDEEFEDMIKSTXRIDFTYGH 645

Query: 593  FFDHVIVNDNLQDACGQLLSAIQKAQEELQWVPEAWV 629
            FFD  IVN  L  A   L+  +Q+ + E  W P  WV
Sbjct: 644  FFDVEIVNGELLAAFEXLVQHVQRLENEPLWAPSMWV 534
>29974
          Length = 344

 Score = 79.7 bits (195), Expect = 3e-15,   Method: Compositional matrix adjust.
 Identities = 43/102 (42%), Positives = 60/102 (58%), Gaps = 1/102 (0%)
 Frame = +1

Query: 446 LIGCNPSCFQSAVPHTTRFPKSYEMDGREYHYVS-RETFESLMYGHKMLEYGEYKGHLYG 504
           LI   P  F S +PHTTR  ++ E  G++YH+VS RE  E  +  H  +E G Y  +LYG
Sbjct: 10  LISEFPDKFGSCIPHTTRERRTNEEPGQDYHFVSSREQMERDIQNHLFIEAGVYNDNLYG 189

Query: 505 TSVNAVHAVLDEGKICIMDLEPQDIQSARTRDLKPYVIFIKP 546
           TSV +V  V ++G+ CI+D+    I+  +   L P  IFIKP
Sbjct: 190 TSVASVKEVAEQGRHCILDVSGNAIKRLQVAGLYPIAIFIKP 315
>29636
          Length = 354

 Score = 72.0 bits (175), Expect = 6e-13,   Method: Compositional matrix adjust.
 Identities = 39/94 (41%), Positives = 57/94 (60%), Gaps = 5/94 (5%)
 Frame = +1

Query: 225 TIMFKVIP----VSAPPVSSQKMVYVRAMIDYWPQEDPDIPCMDAGLPFLKGDILQIVDQ 280
           TI F +IP    V         ++++RA+ +Y P++DP IPC + G+ FLKGDIL  +  
Sbjct: 1   TITFMIIPAHSCVEDTTAKPGDIMHLRALFNYDPEDDPYIPCRELGISFLKGDILHAIQL 180

Query: 281 NDALWWQA-RKISDLTICAGLIPSNHLLKRKQRE 313
           +D+ WWQA R+  D  + AGLIPS     ++QRE
Sbjct: 181 SDSNWWQAHREGEDAHMLAGLIPSKAF--QEQRE 276
>33158
          Length = 1075

 Score = 71.6 bits (174), Expect = 9e-13,   Method: Compositional matrix adjust.
 Identities = 50/161 (31%), Positives = 81/161 (50%), Gaps = 12/161 (7%)
 Frame = +2

Query: 51  LLYDLLHSPWLQALLKVYDCLQRFKEKKLVPD--TTHAQILACEVLELLPKASGSPE--- 105
            L  L H+P  Q  + ++  +     +  +P    + +Q LAC+V     +  GS     
Sbjct: 602 FLKQLFHNPLFQQTVDMHQKMVDVTSRSPLPRPLGSDSQELACDVKSYGSEMGGSXSEAV 781

Query: 106 IQELRQVLQAPHCKALLSAHDTVAQKDFEXXXXXXXDNIPD------SEEAMRIVCLVKN 159
           ++EL  +L  P  K LL AHD VA +           ++ D       EE+++I+ L K 
Sbjct: 782 VEELSMLLDKPALKNLLKAHDEVADQQTHPILHVSESDLIDYPLTEYGEESVKIIHLEKT 961

Query: 160 QQPLGATIKRHEITGD-ILVARVIHGGLVERSGLLYAGDKL 199
            + LGAT+K     GD +L+AR++ GG  E+SGLL+ GD++
Sbjct: 962 NEHLGATVKNE---GDSVLIARIVKGGAAEKSGLLHEGDEI 1075
>08480
          Length = 698

 Score = 66.6 bits (161), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 46/155 (29%), Positives = 70/155 (45%), Gaps = 27/155 (17%)
 Frame = -1

Query: 185 GLVERSGLLYAGDKLVEVNGVSVEGLDPEQVIHILAMSCGTIMFKVIPVSAPP------- 237
           G  + SG L  GDK++ VN V VE    EQ    L  +  T+  ++I    P        
Sbjct: 698 GPADLSGDLRRGDKILSVNDVDVERATHEQAAQALKRAGDTV--EIIAQYKPEDYNRFEA 525

Query: 238 ------------------VSSQKMVYVRAMIDYWPQEDPDIPCMDAGLPFLKGDILQIVD 279
                              + ++ ++VRA+ DY P +D  +P    GL F  GDIL + +
Sbjct: 524 KIQDLREQMMNNSAGSLRTTQKRTMFVRALFDYEPSKDSGLPSR--GLWFHYGDILHVTN 351

Query: 280 QNDALWWQARKI--SDLTICAGLIPSNHLLKRKQR 312
            +D  WWQA++I         G+IPS   ++RK+R
Sbjct: 350 ASDDEWWQAKRILPDGKEEGMGIIPSKRRVERKER 246
>37412
          Length = 757

 Score = 55.5 bits (132), Expect = 7e-08,   Method: Compositional matrix adjust.
 Identities = 41/142 (28%), Positives = 66/142 (46%), Gaps = 11/142 (7%)
 Frame = -1

Query: 480 RETFESLMYGHKMLEYGEYKGHLYGTSVNAVHAVLDEGK-ICIMDLEPQDIQSARTRDLK 538
           R T ES +   + LEYG++ G+LYGT ++ V  ++D G+ +C     P    S R     
Sbjct: 739 RLTMESDIMSGRYLEYGDFNGNLYGTRLDTVRQIVDSGRCVCWTSTLPH*KSSRRPSSC- 563

Query: 539 PYVIFIKPPNTSSMRHSRKNAKITTDY----------YVDMKFKDEDLQEMEELAQKMES 588
                  P   SS R + K +K  T             V++K    +  E  + +Q++E 
Sbjct: 562 -------PTLCSSPRLAWKLSKSCTKMDDGLHAAAGSVVELK*NGGNFIETMKESQQIER 404

Query: 589 QFGQFFDHVIVNDNLQDACGQL 610
            +  +FD +IVND+ +D   QL
Sbjct: 403 VYASYFDDIIVNDSFEDTYRQL 338
>20073
          Length = 582

 Score = 47.8 bits (112), Expect = 1e-05,   Method: Composition-based stats.
 Identities = 23/60 (38%), Positives = 38/60 (63%)
 Frame = +3

Query: 171 EITGDILVARVIHGGLVERSGLLYAGDKLVEVNGVSVEGLDPEQVIHILAMSCGTIMFKV 230
           E +  I ++R+I GG+ +R   L  GD+L+ VNGVSVEG   E+ + +L ++ G++   V
Sbjct: 33  EQSSPIYISRIIPGGVADRLNCLKRGDQLLSVNGVSVEGEYHEKAVELLKLAQGSVRLVV 212
>11574
          Length = 1255

 Score = 38.1 bits (87), Expect = 0.012,   Method: Compositional matrix adjust.
 Identities = 17/46 (36%), Positives = 26/46 (56%)
 Frame = +2

Query: 584 QKMESQFGQFFDHVIVNDNLQDACGQLLSAIQKAQEELQWVPEAWV 629
           + +E  +G FFD  IVN+++ +    L  AI+      QWVP +WV
Sbjct: 8   RAVEKAYGHFFDRQIVNNDIDETIRTLEKAIEDVCTLPQWVPVSWV 145
>26154
          Length = 446

 Score = 34.7 bits (78), Expect = 0.13,   Method: Composition-based stats.
 Identities = 18/51 (35%), Positives = 32/51 (62%), Gaps = 1/51 (1%)
 Frame = -3

Query: 154 VCLVKNQQPLGATIKRHEITGD-ILVARVIHGGLVERSGLLYAGDKLVEVN 203
           V L ++  PLG TI   E   D I+++ +  GGL +++G ++ GD+L+ +N
Sbjct: 222 VQLYRHGGPLGITISGTEDPLDNIVISELTAGGLAQKTGAMHVGDRLLGIN 70
>30740
          Length = 488

 Score = 34.7 bits (78), Expect = 0.13,   Method: Compositional matrix adjust.
 Identities = 12/23 (52%), Positives = 18/23 (78%)
 Frame = +2

Query: 267 LPFLKGDILQIVDQNDALWWQAR 289
           LPF KGDIL+++ +++  WW AR
Sbjct: 233 LPFSKGDILELISKDEEEWWTAR 301
>33804
          Length = 621

 Score = 32.0 bits (71), Expect = 0.77,   Method: Composition-based stats.
 Identities = 16/50 (32%), Positives = 27/50 (54%)
 Frame = -1

Query: 576 LQEMEELAQKMESQFGQFFDHVIVNDNLQDACGQLLSAIQKAQEELQWVP 625
           L++  E A KME +FG++F  V+  D +++   ++ S I        WVP
Sbjct: 567 LRKHFERAIKMEQEFGEYFTGVVQGDTIEEIYSKVKSMIWSQSGPNIWVP 418
>03831
          Length = 1143

 Score = 30.8 bits (68), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 15/40 (37%), Positives = 25/40 (62%)
 Frame = +3

Query: 177 LVARVIHGGLVERSGLLYAGDKLVEVNGVSVEGLDPEQVI 216
            + +V  G   E +GL  AGD++VEVNG ++   + +QV+
Sbjct: 213 FIGKVDEGSPAEAAGL-KAGDRIVEVNGTNIGNENHQQVV 329
>09372
          Length = 1277

 Score = 30.0 bits (66), Expect = 3.2,   Method: Compositional matrix adjust.
 Identities = 21/59 (35%), Positives = 30/59 (50%)
 Frame = +2

Query: 8   AELTNEDRALPTPPDPENGLSGILRLLLQELSLFYSRDVNGLCLLYDLLHSPWLQALLK 66
           A LT     LPT PD   GLS IL+ + + L L  + D +   +  + LH PW+  +L 
Sbjct: 623 ALLTRLTA*LPTLPD-FPGLSRILKSIQKSLILLKNPDFSNFVIFSEFLHLPWVPNVLN 796
>23910
          Length = 657

 Score = 29.6 bits (65), Expect = 3.8,   Method: Compositional matrix adjust.
 Identities = 17/41 (41%), Positives = 26/41 (63%), Gaps = 1/41 (2%)
 Frame = -2

Query: 89  LACEVLELLPKASGSPEIQELRQ-VLQAPHCKALLSAHDTV 128
           LAC+ ++L P  +G   IQ  RQ +L AP C+A+L+ H  +
Sbjct: 656 LACDNIDL-PCRAGQAAIQPARQRLLPAPGCRAVLNVHPCI 537
>17286
          Length = 489

 Score = 28.9 bits (63), Expect = 6.7,   Method: Composition-based stats.
 Identities = 14/52 (26%), Positives = 26/52 (50%)
 Frame = +3

Query: 237 PVSSQKMVYVRAMIDYWPQEDPDIPCMDAGLPFLKGDILQIVDQNDALWWQA 288
           P +  K    RA+ D+ P+ D +       L F +GD++ ++ Q D  W++ 
Sbjct: 3   PTAGVKQPCARAIYDFLPESDGE-------LGFQEGDMITLISQVDENWFEG 137
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|133922578|ref|NP_613069.3| coiled-coil domain
containing 22 [Mus musculus]
         (627 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

24982                                                                 173   2e-43
12129                                                                  29   4.3  
>24982
          Length = 769

 Score =  173 bits (438), Expect = 2e-43,   Method: Compositional matrix adjust.
 Identities = 84/152 (55%), Positives = 113/152 (74%)
 Frame = +1

Query: 475 KQLVSELETLPKDVSRLAYTQRILEIVGNIRKQKEEITKILSDTKELQKEINSLSGKLDR 534
           KQL  E E + KDV+R AYT++I+E  G   KQK+EI ++L DTK LQKEINSL+GKLDR
Sbjct: 19  KQLHMEYERMTKDVNRSAYTRKIMENCGQH*KQKQEIDRVLIDTKSLQKEINSLTGKLDR 198

Query: 535 TFAVTDELVFXXXXXXXXXXXXXXYLAALHENCSQLIQTIEDTGTIMREVRDLEEQIETE 594
           TF VTDEL+F              +LAALHENC Q+ +T+E+TG I+RE+RDLE+QIETE
Sbjct: 199 TFTVTDELIFRDAKKDESVKKAYRFLAALHENCEQVTKTVEETGVIVREIRDLEDQIETE 378

Query: 595 MGKKTLSNLEKICEDYRALRQENAGLLGRVRE 626
             KK L++LEKI +DY+ ++QENA L+ ++++
Sbjct: 379 SHKKVLASLEKITQDYQQMKQENATLMAKLKQ 474
>12129
          Length = 2934

 Score = 29.3 bits (64), Expect = 4.3,   Method: Compositional matrix adjust.
 Identities = 22/99 (22%), Positives = 47/99 (47%), Gaps = 4/99 (4%)
 Frame = +1

Query: 350  EVEADMKTLGINLVQVETECRQSELSVAEQEQALRLKSRTVELLPDGAANLAKLQLVVES 409
            E   D K    N ++    CR S       +  LRLK +T+ ++  GA+ +A +  +V++
Sbjct: 2521 ESTVDRKRKWYNGIRQAVNCRVSTCHYHTSQFCLRLKVQTMPVIKKGAS-VAAIDALVKT 2697

Query: 410  SAQRLIHLA-SQWEK---HRVPLLAEYRHLRRLQDCREL 444
            +   ++ +  S+W+    + +P+  +   L+   D R+ 
Sbjct: 2698 NGDGMVEVTRSRWQSSIVNTIPIGGKRAALKSSSDIRQF 2814
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31542061|ref|NP_758473.2| vacuolar protein sorting 18
[Mus musculus]
         (973 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

18226                                                                 174   2e-43
14302                                                                 151   2e-36
33313                                                                 149   6e-36
33494                                                                 120   4e-30
04908                                                                  31   2.3  
>18226
          Length = 668

 Score =  174 bits (440), Expect = 2e-43,   Method: Compositional matrix adjust.
 Identities = 89/220 (40%), Positives = 137/220 (62%), Gaps = 1/220 (0%)
 Frame = -2

Query: 422 LDTVLAREADFCFRQHRYLESARCYALTQSYFEEIALKFLEARQEEALAEFLQRKLAGLK 481
           L+ VL ++A+  F    Y ESA  YA T + FEE+ALKF+  +++E L  F+  KL  LK
Sbjct: 667 LEQVLIKQAEHLFDAGXYEESAAMYAKTXNPFEEVALKFIRLKEKEPLQTFIMEKLDSLK 488

Query: 482 PTERXXXXXXXXXXXXXXXSRLGALQGDP-DALTLYRDTRECFRTFLSSPRHKEWLFASR 540
           P ++               + LG L+    D  + Y   ++  RTF+ + R KE +  +R
Sbjct: 487 PQDKTQLTMLVTWLVELFLTSLGKLKDRGLDETSEYDTIQDKLRTFMRNXRVKECMTLNR 308

Query: 541 ASIHELLASHGDTEHMVYFAVIMQDYERVVAYHCQHEAYEEALAVLARHRDPQLFYKFSP 600
           + I++L+ASHGD E +V+FA +M+DYERV+++H QHE ++ AL  L +    +L+YKFSP
Sbjct: 307 SVIYDLIASHGDVEDLVFFARLMEDYERVISHHIQHENFKGALECLIKQPSIELYYKFSP 128

Query: 601 ILIRHIPRQLVDAWIEMGSRLDARQLIPALVNYSQGGEAQ 640
           +L++++P+  VDAWI+ G +LD ++LIPALV Y Q G  Q
Sbjct: 127 LLMQYLPKDTVDAWIKQGRQLDPKRLIPALVQYDQRGREQ 8
>14302
          Length = 452

 Score =  151 bits (381), Expect = 2e-36,   Method: Composition-based stats.
 Identities = 72/148 (48%), Positives = 106/148 (71%)
 Frame = -3

Query: 693 VHYDLKYALRLCAEHGHHRACVHVYKVLELYEEAVDLALQVDVDLAKQCADLPEEDEELR 752
           VHYD+ +AL++C + G   ACV +  +L ++  AVDLAL+ DV LAK+ A  P+ D E R
Sbjct: 441 VHYDIHFALKVCTDLGVKEACVFLQCMLCMWTTAVDLALEFDVSLAKKTASKPQ-DNETR 265

Query: 753 KKLWLKIARHVVQEEEDVQTAMACLASCPLLKIEDVLPFFPDFVTIDHFKEAICSSLKAY 812
           +KLWL+IA H ++   DV+ A++ L  C LL+IED+LPFF DF  ID+FKEAIC +LK Y
Sbjct: 264 RKLWLRIAYHDIKGTNDVKKALSLLKECDLLRIEDLLPFFSDFEKIDNFKEAICDALKDY 85

Query: 813 NHHIQELQREMEEATASAQRIRRDLQEL 840
           N  +QELQ++M E+   ++R+ ++L++L
Sbjct: 84  NQRLQELQKDMAESKDQSERVCKELRQL 1
>33313
          Length = 566

 Score =  149 bits (375), Expect = 6e-36,   Method: Compositional matrix adjust.
 Identities = 83/168 (49%), Positives = 108/168 (64%), Gaps = 6/168 (3%)
 Frame = -3

Query: 735 VDLAKQCADLPEEDE-ELRKKLWLKIARHVVQEEEDVQTAMACL-ASCPLLKIED---VL 789
           V+LAKQ A+ P+ED+ ELRKK    +  H        +   +C   S  +   +D     
Sbjct: 564 VELAKQQANKPDEDDLELRKKT---VVTHCASRCSR*ERRASCHGVSARV*HAQD*RHPC 394

Query: 790 PFFPDFVTIDHFKEAICSSLKAYNHHIQELQREMEEATASAQRIRRDLQELRGRYGTVEP 849
           PFFPDFVTIDHFK+AI SSL+ YNHHI  L+ EMEEAT SA+ IRR++Q  R +Y  V+ 
Sbjct: 393 PFFPDFVTIDHFKDAIISSLQEYNHHIDSLKEEMEEATQSAEEIRREIQSFRNKYTLVKA 214

Query: 850 QDKCSTCDFPLLNR-PFYLFLCGHMFHADCLLQAVRPGLPAYKQARLE 896
           +DKCS C +PL+ R PFYLF C H FH DCL+  V P L A K++++E
Sbjct: 213 EDKCSVCSYPLMTRPPFYLFPCTHKFHMDCLIAEVLPSLQASKKSQVE 70
>33494
          Length = 543

 Score =  120 bits (302), Expect(2) = 4e-30,   Method: Composition-based stats.
 Identities = 63/163 (38%), Positives = 89/163 (54%), Gaps = 6/163 (3%)
 Frame = -2

Query: 231 FIGRAVEDTEAQGFAGLFAAY---TDHPPPFREFPSNLGYSELAFYTPKLRSAPRAFAWM 287
           FIG      E   F  LF  Y   TDHP  F E P N GYS+L  + PK R A   FAW+
Sbjct: 542 FIGTVSTSAEPPMFTPLFQPYETGTDHPQ-FLELPGNFGYSDLHLFFPKFRQAAHTFAWL 366

Query: 288 MGDGVLYGSLDC---GRPDSLLSEERVWEYPAGVGPGANPPLAIVLTQFHFLLLLADRVE 344
            G GV +G++D      P+S+++  ++  Y          P+++VLT+FH L+L   R++
Sbjct: 365 TGPGVYFGNIDVTGSAGPNSVMANAKLIPYSRDSEDQGANPISMVLTEFHMLILFPSRMK 186

Query: 345 AVCTLTGQVVLRDHFLEKFGPLRHMVKDSSTGHLWAYTERAVF 387
           AVC+L  Q +  D   E+FG L  + KD   G +W+YT +AVF
Sbjct: 185 AVCSLNEQTIFDDAIPERFGRLLGIKKDPIRGSIWSYTSQAVF 57

 Score = 30.0 bits (66), Expect(2) = 4e-30,   Method: Compositional matrix adjust.
 Identities = 13/21 (61%), Positives = 14/21 (66%)
 Frame = -3

Query: 384 RAVFRYHVQREARDVWRTYLD 404
           R  F Y V REARDVW+ YL 
Sbjct: 67  RLSFVYKVAREARDVWQMYLS 5
>04908
          Length = 1856

 Score = 31.2 bits (69), Expect = 2.3,   Method: Compositional matrix adjust.
 Identities = 21/53 (39%), Positives = 30/53 (56%), Gaps = 6/53 (11%)
 Frame = -1

Query: 673 RGQTASLLAYLEQAG--ASPHRVHYDLKYALRLC----AEHGHHRACVHVYKV 719
           RG TAS++AY+E  G  A P  V ++L   +RL     + HG HR  V+  +V
Sbjct: 413 RGHTASVVAYIEDFGFDADPVEVSHELPACVRLASSGQSHHGDHRGPVNHERV 255
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6755120|ref|NP_035259.1| septin 4 [Mus musculus]
         (478 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

14132                                                                 172   2e-43
34156                                                                 117   8e-27
22078                                                                 112   2e-25
14677                                                                  84   4e-20
29788                                                                  77   1e-14
01347                                                                  30   1.8  
>14132
          Length = 422

 Score =  172 bits (437), Expect = 2e-43,   Method: Compositional matrix adjust.
 Identities = 80/142 (56%), Positives = 106/142 (74%), Gaps = 1/142 (0%)
 Frame = -2

Query: 212 FGDAVNNTECWKPVAEYIDQQFEQYFRDESGLNRKNIQDNRVHCCLYFISPFGHGLRPLD 271
           FGDAV+N+ CW+P+ +YID ++E+Y   ES +NR  + D RVHCCLYFI+P GHGL+PLD
Sbjct: 421 FGDAVDNSNCWQPITDYIDSKYEEYLNAESRVNRTVMPDTRVHCCLYFIAPTGHGLKPLD 242

Query: 272 VEFMKALHQRVNIVPILAKADTLTPPEVDRKKCKIREEIEHFGIKIYQFPDCDSDEDEDF 331
           VEFMK LH +VNI+P++AKADTLTP E    K  I  EI    IKIY+FPDC  D++E+ 
Sbjct: 241 VEFMKRLHDKVNIIPLVAKADTLTPDECREFKKTILNEIAQHKIKIYEFPDC--DDEEEM 68

Query: 332 KLQDQA-LKESIPFAVIGSNTV 352
           K+Q +  + + +PFAV+GSN V
Sbjct: 67  KIQKRLRVSDRVPFAVVGSNRV 2
>34156
          Length = 348

 Score =  117 bits (294), Expect = 8e-27,   Method: Compositional matrix adjust.
 Identities = 58/79 (73%), Positives = 67/79 (84%)
 Frame = -1

Query: 131 PNQVHRKSVKKGFDFTLMVAGESGLGKSTLVNSLFLTDLYRDRKLLGAEERIMQTVEITK 190
           P QVHRKSVKKGF+FTLMV GESGLGKSTLVNSLFLTDLY +R +  A E+I QTV+I  
Sbjct: 237 PTQVHRKSVKKGFEFTLMVVGESGLGKSTLVNSLFLTDLYPERHIPSASEKIQQTVKIDA 58

Query: 191 HAVDIEEKGVRLRLTIVDT 209
             V+IEE+GV+LRLT+VDT
Sbjct: 57  STVEIEERGVKLRLTVVDT 1
>22078
          Length = 417

 Score =  112 bits (281), Expect = 2e-25,   Method: Compositional matrix adjust.
 Identities = 56/110 (50%), Positives = 76/110 (69%)
 Frame = +3

Query: 365 YPWGIVEVENPGHCDFVKLRTMLVRTHMQDLKDVTRETHYENYRAQCIQSMTRLVVKERN 424
           YPWGIVEV+N  HCDF++LR ML+ THMQDLKDVT + HYEN+R+  IQ    L  + R 
Sbjct: 15  YPWGIVEVDNXSHCDFIRLRQMLISTHMQDLKDVTSDVHYENFRSSFIQQ--SLAAQHRE 188

Query: 425 RNKLTRESGTDFPIPAVPPGTDPETEKLIREKDEELRRMQEMLHKIQRQM 474
           R+KL R+S      P    G D +T  L+++KD E++RMQ+ML ++Q Q+
Sbjct: 189 RSKLKRDSK-----PCEEDGMDTDT--LLQQKDAEIQRMQQMLARMQEQL 317
>14677
          Length = 378

 Score = 84.3 bits (207), Expect(2) = 4e-20,   Method: Composition-based stats.
 Identities = 37/76 (48%), Positives = 51/76 (67%), Gaps = 2/76 (2%)
 Frame = -1

Query: 186 VEITKHAVDIEEKGVRLRLTIVDTPGFGDAVNNTECWKPVAEYIDQQFEQYFRDESGLNR 245
           V++  H  D+ EK VRL+LT VDT GFGD +N  + WKP+ +YID QF+ Y ++E  + R
Sbjct: 228 VKLKAHTYDLTEKNVRLKLTTVDTTGFGDQINKADSWKPIVDYIDAQFDAYLQEELKIKR 49

Query: 246 --KNIQDNRVHCCLYF 259
              +  D+RVH CLYF
Sbjct: 48  MLHSYHDSRVHACLYF 1

 Score = 31.6 bits (70), Expect(2) = 4e-20,   Method: Composition-based stats.
 Identities = 13/24 (54%), Positives = 19/24 (79%)
 Frame = -3

Query: 146 TLMVAGESGLGKSTLVNSLFLTDL 169
           T  V GE+G+GKSTL+++LF T+ 
Sbjct: 334 TFFVLGETGIGKSTLMDTLFNTNF 263
>29788
          Length = 687

 Score = 77.0 bits (188), Expect = 1e-14,   Method: Compositional matrix adjust.
 Identities = 32/43 (74%), Positives = 35/43 (81%)
 Frame = +3

Query: 366 PWGIVEVENPGHCDFVKLRTMLVRTHMQDLKDVTRETHYENYR 408
           PWGIVEVEN  H DF+ LR ML+RTHMQDLKDVT   HYEN+R
Sbjct: 3   PWGIVEVENLEHNDFIALRNMLIRTHMQDLKDVTNNVHYENFR 131
>01347
          Length = 1266

 Score = 30.4 bits (67), Expect = 1.8,   Method: Compositional matrix adjust.
 Identities = 15/43 (34%), Positives = 22/43 (51%)
 Frame = +2

Query: 406 NYRAQCIQSMTRLVVKERNRNKLTRESGTDFPIPAVPPGTDPE 448
           N   +CIQ   R   +E+NR +LTR     F + + P  T P+
Sbjct: 803 NLVTKCIQLFHRFSSQEKNRAELTRICQEQFVVVSRPXATAPK 931
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|95772123|ref|NP_082168.1| protein phosphatase 1,
regulatory (inhibitor) subunit 12A [Mus musculus]
         (1004 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

09180                                                                 174   2e-43
28494                                                                 164   4e-41
06253                                                                  94   2e-19
05924                                                                  77   3e-14
09292                                                                  69   1e-11
14005                                                                  63   5e-10
25470                                                                  63   7e-10
11295                                                                  62   9e-10
00540                                                                  61   3e-09
02114                                                                  60   3e-09
19166                                                                  59   1e-08
13462                                                                  54   3e-07
02055                                                                  52   1e-06
12417                                                                  50   6e-06
15359                                                                  49   8e-06
21532                                                                  49   8e-06
30463                                                                  49   1e-05
08473                                                                  49   1e-05
15772                                                                  48   2e-05
28113                                                                  46   6e-05
28691                                                                  46   8e-05
17893                                                                  45   1e-04
20036                                                                  45   2e-04
38834                                                                  43   6e-04
36917                                                                  42   0.001
25464                                                                  40   0.003
27108                                                                  40   0.004
22305                                                                  40   0.004
34789                                                                  40   0.005
16561                                                                  40   0.005
35952                                                                  39   0.008
20792                                                                  39   0.010
27067                                                                  38   0.020
21751                                                                  38   0.025
11861                                                                  36   0.074
08755                                                                  35   0.15 
02050                                                                  35   0.17 
02351                                                                  34   0.25 
05396                                                                  34   0.27 
30978                                                                  33   0.57 
09214                                                                  33   0.71 
28345                                                                  33   0.76 
30217                                                                  33   0.77 
20988                                                                  32   1.6  
33144                                                                  32   1.6  
34070                                                                  31   2.2  
26054                                                                  30   6.6  
20884                                                                  29   9.0  
>09180
          Length = 610

 Score =  174 bits (441), Expect = 2e-43,   Method: Compositional matrix adjust.
 Identities = 75/135 (55%), Positives = 104/135 (77%)
 Frame = +3

Query: 156 QNEVNRQGVDIEAARKEEERVMLRDARQWLNSGHISDVRHAKSGGTALHVAAAKGYTEVL 215
           Q E++++GVD +AARKEEE +M+ DA +WL + +I D  H K+G TALHV+AAKGY  V+
Sbjct: 36  QKEMDKKGVDADAARKEEEDMMMEDANRWLQNKNIEDNAHPKTGATALHVSAAKGYINVM 215

Query: 216 KLLIQAGYDVNIKDYDGWTPLHAAAHWGKEEACRILVDNLCDMETVNKVGQTAFDVADED 275
            +L+QAG D+N +D DGWT LHAA HWG+E++C++LVD+ CDM+  N  G T FD+AD++
Sbjct: 216 NVLLQAGVDINAQDADGWTSLHAAVHWGQEDSCQVLVDHFCDMDVKNNAGHTVFDLADKE 395

Query: 276 ILGYLEELQKKQTLL 290
           +L  LEEL+KKQ  L
Sbjct: 396 MLKVLEELKKKQAKL 440

 Score = 48.5 bits (114), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 23/73 (31%), Positives = 37/73 (50%)
 Frame = +3

Query: 73  GLTALHQACIDDNVDMVKFLVENGANINQPDNEGWIPLHAAASCGYLDIAEFLIGQGAHV 132
           G TALH +     ++++  L++ G +IN  D +GW  LHAA   G  D  + L+     +
Sbjct: 165 GATALHVSAAKGYINVMNVLLQAGVDINAQDADGWTSLHAAVHWGQEDSCQVLVDHFCDM 344

Query: 133 GAVNSEGDTPLDI 145
              N+ G T  D+
Sbjct: 345 DVKNNAGHTVFDL 383

 Score = 32.3 bits (72), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 17/48 (35%), Positives = 26/48 (54%)
 Frame = +3

Query: 59  LLHRGADINYANVDGLTALHQACIDDNVDMVKFLVENGANINQPDNEG 106
           LL  G DIN  + DG T+LH A      D  + LV++  +++  +N G
Sbjct: 222 LLQAGVDINAQDADGWTSLHAAVHWGQEDSCQVLVDHFCDMDVKNNAG 365
>28494
          Length = 463

 Score =  164 bits (415), Expect(2) = 4e-41,   Method: Compositional matrix adjust.
 Identities = 80/121 (66%), Positives = 92/121 (76%)
 Frame = -1

Query: 14  LKRWIGSETDLEPPVVKRQKTKVKFDDGAVFLAACSSGDTDEVLKLLHRGADINYANVDG 73
           LKRW  SET+ E    +    KVKF DG VFLAACSSGD DEV KLL RGADIN ANVDG
Sbjct: 397 LKRWEDSETNRELGYPRPSAKKVKFQDGCVFLAACSSGDRDEVKKLLERGADINTANVDG 218

Query: 74  LTALHQACIDDNVDMVKFLVENGANINQPDNEGWIPLHAAASCGYLDIAEFLIGQGAHVG 133
           LTALHQACIDDN+DMV+FLVE  A+++  DNEGW PLHA ASCG+ +IA +L+  GA+ G
Sbjct: 217 LTALHQACIDDNLDMVEFLVEQNADVDVCDNEGWTPLHATASCGFTEIARYLLENGANGG 38

Query: 134 A 134
            
Sbjct: 37  C 35

 Score = 23.9 bits (50), Expect(2) = 4e-41,   Method: Composition-based stats.
 Identities = 9/14 (64%), Positives = 12/14 (85%)
 Frame = -2

Query: 132 VGAVNSEGDTPLDI 145
           VGAVN++GD  +DI
Sbjct: 42  VGAVNNDGDLAIDI 1

 Score = 47.4 bits (111), Expect = 3e-05,   Method: Composition-based stats.
 Identities = 25/65 (38%), Positives = 38/65 (58%), Gaps = 1/65 (1%)
 Frame = -1

Query: 191 SDVRHAKSGG-TALHVAAAKGYTEVLKLLIQAGYDVNIKDYDGWTPLHAAAHWGKEEACR 249
           +D+  A   G TALH A      ++++ L++   DV++ D +GWTPLHA A  G  E  R
Sbjct: 247 ADINTANVDGLTALHQACIDDNLDMVEFLVEQNADVDVCDNEGWTPLHATASCGFTEIAR 68

Query: 250 ILVDN 254
            L++N
Sbjct: 67  YLLEN 53
>06253
          Length = 1049

 Score = 94.4 bits (233), Expect = 2e-19,   Method: Compositional matrix adjust.
 Identities = 72/222 (32%), Positives = 107/222 (48%)
 Frame = -1

Query: 31   RQKTKVKFDDGAVFLAACSSGDTDEVLKLLHRGADINYANVDGLTALHQACIDDNVDMVK 90
            R+ T + F  G         G  D V  LL  GA+++  +  GL  LH AC   + ++V+
Sbjct: 1049 RKSTPLHFAAG--------FGRKDVVEHLLENGANVHARDDGGLIPLHNACSFGHAEVVQ 894

Query: 91   FLVENGANINQPDNEGWIPLHAAASCGYLDIAEFLIGQGAHVGAVNSEGDTPLDIXXXXX 150
             L+ +GA+ N  DN  + PLH AA  G +D+   L+ Q A     N++G T LD+     
Sbjct: 893  LLLRHGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQQCADPNIRNTDGKTALDLADASA 714

Query: 151  XXXXXQNEVNRQGVDIEAARKEEERVMLRDARQWLNSGHISDVRHAKSGGTALHVAAAKG 210
                   E  +  + +EAAR   E  M+        + H SD R +    T LH+AA   
Sbjct: 713  KAVLT-GEYKKDEL-LEAARSGNEEQMMALLTPLNVNCHASDGRKS----TPLHLAAGYN 552

Query: 211  YTEVLKLLIQAGYDVNIKDYDGWTPLHAAAHWGKEEACRILV 252
             T +++LL+Q G DV+ KD  G  PLH A  +G  E   +L+
Sbjct: 551  RTRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHFEVTEMLL 426

 Score = 71.2 bits (173), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 50/171 (29%), Positives = 87/171 (50%), Gaps = 3/171 (1%)
 Frame = -1

Query: 59  LLHRGADINYANVDGLTALHQACIDDNVDMVKFLVENGANINQPDNEGWIPLHAAASCGY 118
           LL  GAD++  +  GL  LH AC   + ++ + L+  GA++N  D   + PLH AAS   
Sbjct: 530 LLQHGADVHAKDKGGLVPLHNACSYGHFEVTEMLLXAGASVNAVDLWQFTPLHEAASKSR 351

Query: 119 LDIAEFLIGQGAHVGAVNSEGDTPLDIXXXXXXXXXXQNEVNRQGVDIEAARKEEERVML 178
           +++   L+  GA    VN    + +D+          Q E     + +E AR+ +    L
Sbjct: 350 VEVCSLLLAHGADPNLVNCHSKSIIDVAPTRELQERIQFEYKGHSL-LEGARQAD----L 186

Query: 179 RDARQWLNSGHISDVRHAKSGGTALHVAAAKGYT---EVLKLLIQAGYDVN 226
              +++L +  I + +H  +G TALH AAA  +    +V++LL++ G ++N
Sbjct: 185 ARVKKYL-AVDIVNFKHPYNGDTALHCAAASPFPKRKQVVELLVRKGGNLN 36
>05924
          Length = 704

 Score = 77.4 bits (189), Expect = 3e-14,   Method: Composition-based stats.
 Identities = 71/261 (27%), Positives = 112/261 (42%), Gaps = 1/261 (0%)
 Frame = +1

Query: 52  DTDEVLKLLHRGADINYANVDGLTALHQACIDDNVDMVKFLVENGANINQPDNEGWIPLH 111
           D   V +L+  G D+N       T LH+A    + D+V+ L++ GAN N  + +G   LH
Sbjct: 1   DHKAVQRLVKGGVDVNARFWYDSTLLHEAVSMASEDLVQMLIKAGANANSTNQDGRTALH 180

Query: 112 AAASCGYLDIAEFLIGQGAHVGAVNSEGDTPLDIXXXXXXXXXXQNEVNRQGVDIEAARK 171
            A   GY +I + LI  G  V     +G T L +                        R 
Sbjct: 181 LACRGGYTNIVQILIAAGTDVNRRTVDGKTCLHVA---------------------VWRG 297

Query: 172 EEERVMLRDARQWLNSGHISDVRHAKS-GGTALHVAAAKGYTEVLKLLIQAGYDVNIKDY 230
             E V+     + +N+G  +DV    S G + L+ AA   YT +L +L+ AG  VN +  
Sbjct: 298 HTEVVV-----KLVNAG--ADVNIPDSVGCSPLYWAARSNYTAILTVLVNAGAKVNYRVK 456

Query: 231 DGWTPLHAAAHWGKEEACRILVDNLCDMETVNKVGQTAFDVADEDILGYLEELQKKQTLL 290
             WTPLHAA H G     R L         + +  +T   V D+ ++  L +    + L 
Sbjct: 457 SKWTPLHAALHLGHMGVVRYL---------LLQGAETNITVQDKTVVSLLMD---NEHLS 600

Query: 291 HSEKRDKKSPLIESTANMENN 311
           H E+    + L+++  N+  +
Sbjct: 601 HKERERTLAMLVKAGYNLHKD 663

 Score = 59.3 bits (142), Expect = 7e-09,   Method: Composition-based stats.
 Identities = 38/97 (39%), Positives = 49/97 (50%)
 Frame = +1

Query: 47  ACSSGDTDEVLKLLHRGADINYANVDGLTALHQACIDDNVDMVKFLVENGANINQPDNEG 106
           AC  G T+ V  L+  G D+N   VDG T LH A    + ++V  LV  GA++N PD+ G
Sbjct: 184 ACRGGYTNIVQILIAAGTDVNRRTVDGKTCLHVAVWRGHTEVVVKLVNAGADVNIPDSVG 363

Query: 107 WIPLHAAASCGYLDIAEFLIGQGAHVGAVNSEGDTPL 143
             PL+ AA   Y  I   L+  GA V        TPL
Sbjct: 364 CSPLYWAARSNYTAILTVLVNAGAKVNYRVKSKWTPL 474

 Score = 54.7 bits (130), Expect = 2e-07,   Method: Composition-based stats.
 Identities = 32/92 (34%), Positives = 49/92 (53%), Gaps = 1/92 (1%)
 Frame = +1

Query: 40  DGAVFL-AACSSGDTDEVLKLLHRGADINYANVDGLTALHQACIDDNVDMVKFLVENGAN 98
           DG   L  A   G T+ V+KL++ GAD+N  +  G + L+ A   +   ++  LV  GA 
Sbjct: 259 DGKTCLHVAVWRGHTEVVVKLVNAGADVNIPDSVGCSPLYWAARSNYTAILTVLVNAGAK 438

Query: 99  INQPDNEGWIPLHAAASCGYLDIAEFLIGQGA 130
           +N      W PLHAA   G++ +  +L+ QGA
Sbjct: 439 VNYRVKSKWTPLHAALHLGHMGVVRYLLLQGA 534
>09292
          Length = 1486

 Score = 68.6 bits (166), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 61/226 (26%), Positives = 98/226 (43%), Gaps = 36/226 (15%)
 Frame = -2

Query: 51   GDTDEVLKLLHRGADINYANVDGLTALHQACIDDNVDMVKFLVENGANIN-------QPD 103
            G    V +L+  GAD N  + D LT +  AC+ ++ D+V++L+E+GA  N          
Sbjct: 1230 GHLGLVEELVRHGADFNAEDKDHLTPVFNACVKNDTDIVRYLLESGARANTTARPIFHAV 1051

Query: 104  NEGW---------------------IPLHAAASCGYLDIAEFLIGQGAHVGAVNSEGDTP 142
              G+                      PLH A   G +++A  +I  GA+V AV+ +G+TP
Sbjct: 1050 KYGYSEIVQLLLVHGAAVNSLPGTKSPLHIACRNGNIEMARTVIIAGANVNAVDKDGNTP 871

Query: 143  LDIXXXXXXXXXXQNEVNRQGVDIEAARKEEERVM--------LRDARQWLNSGHISDVR 194
            L I             + R G +++     ++  +        L  AR  L+ G  S+  
Sbjct: 870  LHISVRAPSSAQLVRLLIRFGANVKWGNDNQQIPLHLACLYSNLETARLLLHCGSCSNEL 691

Query: 195  HAKSGGTALHVAAAKGYTEVLKLLIQAGYDVNIKDYDGWTPLHAAA 240
             +K   T LH A   G  ++++L++Q   DVN  D     PLH A 
Sbjct: 690  SSKL-WTPLHYAVIGGNVDIVRLVLQGSSDVNSPDGRNNAPLHLAC 556

 Score = 57.0 bits (136), Expect = 4e-08,   Method: Compositional matrix adjust.
 Identities = 45/182 (24%), Positives = 82/182 (45%), Gaps = 1/182 (0%)
 Frame = -2

Query: 55  EVLKLLHR-GADINYANVDGLTALHQACIDDNVDMVKFLVENGANINQPDNEGWIPLHAA 113
           ++++LL R GA++ + N +    LH AC+  N++  + L+  G+  N+  ++ W PLH A
Sbjct: 837 QLVRLLIRFGANVKWGNDNQQIPLHLACLYSNLETARLLLHCGSCSNELSSKLWTPLHYA 658

Query: 114 ASCGYLDIAEFLIGQGAHVGAVNSEGDTPLDIXXXXXXXXXXQNEVNRQGVDIEAARKEE 173
              G +DI   ++   + V + +   + PL +               +Q + I       
Sbjct: 657 VIGGNVDIVRLVLQGSSDVNSPDGRNNAPLHLACM------------KQCIGI------- 535

Query: 174 ERVMLRDARQWLNSGHISDVRHAKSGGTALHVAAAKGYTEVLKLLIQAGYDVNIKDYDGW 233
            R +LR       SG+        +G T LH+A +    E++ LL   G +  + D+DG 
Sbjct: 534 ARCLLRHGANVNVSGY--------NGRTPLHIAISHHNLELVLLLYMCGANDQLVDFDGN 379

Query: 234 TP 235
            P
Sbjct: 378 FP 373

 Score = 55.5 bits (132), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 53/202 (26%), Positives = 87/202 (43%), Gaps = 13/202 (6%)
 Frame = -2

Query: 51   GDTDEVLKLLHRGADINYANVDGL-TALHQACIDDNVDMVKFLVENGANINQPDNEGWIP 109
            G ++ V  LL  GA +N  ++ G  + LH AC + N++M + ++  GAN+N  D +G  P
Sbjct: 1044 GYSEIVQLLLVHGAAVN--SLPGTKSPLHIACRNGNIEMARTVIIAGANVNAVDKDGNTP 871

Query: 110  LHAAA-SCGYLDIAEFLIGQGAHVGAVNSEGDTPLDIXXXXXXXXXXQNEVNRQGVDIEA 168
            LH +  +     +   LI  GA+V   N     PL +            E  R  +   +
Sbjct: 870  LHISVRAPSSAQLVRLLIRFGANVKWGNDNQQIPLHLACLYSNL-----ETARLLLHCGS 706

Query: 169  ARKEEERVMLRDARQWLNSGHISDVRHAKSGGT-----------ALHVAAAKGYTEVLKL 217
               E    +       +  G++  VR    G +            LH+A  K    + + 
Sbjct: 705  CSNELSSKLWTPLHYAVIGGNVDIVRLVLQGSSDVNSPDGRNNAPLHLACMKQCIGIARC 526

Query: 218  LIQAGYDVNIKDYDGWTPLHAA 239
            L++ G +VN+  Y+G TPLH A
Sbjct: 525  LLRHGANVNVSGYNGRTPLHIA 460

 Score = 55.1 bits (131), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 34/99 (34%), Positives = 49/99 (49%)
 Frame = -2

Query: 47  ACSSGDTDEVLKLLHRGADINYANVDGLTALHQACIDDNVDMVKFLVENGANINQPDNEG 106
           AC   + +    LLH G+  N  +    T LH A I  NVD+V+ +++  +++N PD   
Sbjct: 759 ACLYSNLETARLLLHCGSCSNELSSKLWTPLHYAVIGGNVDIVRLVLQGSSDVNSPDGRN 580

Query: 107 WIPLHAAASCGYLDIAEFLIGQGAHVGAVNSEGDTPLDI 145
             PLH A     + IA  L+  GA+V      G TPL I
Sbjct: 579 NAPLHLACMKQCIGIARCLLRHGANVNVSGYNGRTPLHI 463

 Score = 55.1 bits (131), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 53/196 (27%), Positives = 83/196 (42%), Gaps = 10/196 (5%)
 Frame = -2

Query: 52   DTDEVLKLLHRGADINYANVDGLTALHQACIDDNVDMVKFLVENGANINQPDNEGWIPLH 111
            D + +L  L  G  ++  +    TALH  C   +V M   L+++ A++N  +N    PLH
Sbjct: 1425 DVETLLAYLDIGMHVDTRDSHHETALHAVCYVGSVKMASVLLKHXADVNARNNVDRTPLH 1246

Query: 112  AAASCGYLDIAEFLIGQGAHVGAVNSEGDTPL---------DIXXXXXXXXXXQNEVNRQ 162
              A  G+L + E L+  GA   A + +  TP+         DI           N   R 
Sbjct: 1245 IXAIEGHLGLVEELVRHGADFNAEDKDHLTPVFNACVKNDTDIVRYLLESGARANTTARP 1066

Query: 163  GVD-IEAARKEEERVMLRDARQWLNSGHISDVRHAKSGGTALHVAAAKGYTEVLKLLIQA 221
                ++    E  +++L          H + V       + LH+A   G  E+ + +I A
Sbjct: 1065 IFHAVKYGYSEIVQLLLV---------HGAAVNSLPGTKSPLHIACRNGNIEMARTVIIA 913

Query: 222  GYDVNIKDYDGWTPLH 237
            G +VN  D DG TPLH
Sbjct: 912  GANVNAVDKDGNTPLH 865

 Score = 46.2 bits (108), Expect = 7e-05,   Method: Compositional matrix adjust.
 Identities = 56/210 (26%), Positives = 89/210 (42%), Gaps = 11/210 (5%)
 Frame = -2

Query: 74   LTALHQACIDDNVDMVKFLVENGANINQPDNEGWIPLHAAASCGYLDIAEFLIGQGAHVG 133
              ALH A    +V+ +   ++ G +++  D+     LHA    G + +A  L+   A V 
Sbjct: 1458 FCALHCAXQLQDVETLLAYLDIGMHVDTRDSHHETALHAVCYVGSVKMASVLLKHXADVN 1279

Query: 134  AVNSEGDTPLDIXXXXXXXXXXQNEVNRQGVDIEAARKEEERVMLRDA--------RQWL 185
            A N+   TPL I          + E+ R G D  A  K+    +            R  L
Sbjct: 1278 ARNNVDRTPLHIXAIEGHLGLVE-ELVRHGADFNAEDKDHLTPVFNACVKNDTDIVRYLL 1102

Query: 186  NSGHISDVRHAKSGGTA--LHVAAAKGYTEVLKLLIQAGYDVNIKDYDGW-TPLHAAAHW 242
             SG       A++  TA  +  A   GY+E+++LL+  G  VN     G  +PLH A   
Sbjct: 1101 ESG-------ARANTTARPIFHAVKYGYSEIVQLLLVHGAAVN--SLPGTKSPLHIACRN 949

Query: 243  GKEEACRILVDNLCDMETVNKVGQTAFDVA 272
            G  E  R ++    ++  V+K G T   ++
Sbjct: 948  GNIEMARTVIIAGANVNAVDKDGNTPLHIS 859

 Score = 44.3 bits (103), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 28/92 (30%), Positives = 46/92 (50%)
 Frame = -2

Query: 51  GDTDEVLKLLHRGADINYANVDGLTALHQACIDDNVDMVKFLVENGANINQPDNEGWIPL 110
           G+ D V  +L   +D+N  +      LH AC+   + + + L+ +GAN+N     G  PL
Sbjct: 648 GNVDIVRLVLQGSSDVNSPDGRNNAPLHLACMKQCIGIARCLLRHGANVNVSGYNGRTPL 469

Query: 111 HAAASCGYLDIAEFLIGQGAHVGAVNSEGDTP 142
           H A S   L++   L   GA+   V+ +G+ P
Sbjct: 468 HIAISHHNLELVLLLYMCGANDQLVDFDGNFP 373

 Score = 42.7 bits (99), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 29/107 (27%), Positives = 48/107 (44%), Gaps = 1/107 (0%)
 Frame = -2

Query: 201  TALHVAAAKGYTEVLKLLIQAGYDVNIKDYDGWTPLHAAAHWGKEEACRILVDNLCDMET 260
             ALH A      E L   +  G  V+ +D    T LHA  + G  +   +L+ +  D+  
Sbjct: 1455 CALHCAXQLQDVETLLAYLDIGMHVDTRDSHHETALHAVCYVGSVKMASVLLKHXADVNA 1276

Query: 261  VNKVGQTAFDV-ADEDILGYLEELQKKQTLLHSEKRDKKSPLIESTA 306
             N V +T   + A E  LG +EEL +     ++E +D  +P+  +  
Sbjct: 1275 RNNVDRTPLHIXAIEGHLGLVEELVRHGADFNAEDKDHLTPVFNACV 1135
>14005
          Length = 1745

 Score = 63.2 bits (152), Expect = 5e-10,   Method: Compositional matrix adjust.
 Identities = 59/209 (28%), Positives = 92/209 (44%), Gaps = 1/209 (0%)
 Frame = -1

Query: 53   TDEVLKLLHRGADINYANVDGLTALHQACIDDNVDMVKFLVENGANINQPDNEG-WIPLH 111
              E+LK+   G D+N  +     AL+ AC+ +++++VK LV  GA +N    E  W P H
Sbjct: 1697 VSELLKV--PGIDVNERDEKLRPALYFACMGNDIELVKQLVRYGARVNAYSTETWWTPFH 1524

Query: 112  AAASCGYLDIAEFLIGQGAHVGAVNSEGDTPLDIXXXXXXXXXXQNEVNRQGVDIEAARK 171
            A    G   IA +L+  GA+  +   +G TPL                      + A + 
Sbjct: 1523 ACCKRGDPRIALYLLRHGANKESRTVDGKTPL----------------------VVACKN 1410

Query: 172  EEERVMLRDARQWLNSGHISDVRHAKSGGTALHVAAAKGYTEVLKLLIQAGYDVNIKDYD 231
            ++  V L   R   N     D+    +  T +H A  +   E+LK L+  G DV+  +  
Sbjct: 1409 DKAEVALLLIRSGANVNVSCDI----TANTPVHFACQRPNIELLKRLVLHGADVDKPNAK 1242

Query: 232  GWTPLHAAAHWGKEEACRILVDNLCDMET 260
            G T LH A+  G ++    L+D  CD E 
Sbjct: 1241 GHTALHVASVRGFKQHVIYLLD-FCDAEV 1158

 Score = 60.1 bits (144), Expect = 5e-09,   Method: Compositional matrix adjust.
 Identities = 50/197 (25%), Positives = 83/197 (42%), Gaps = 1/197 (0%)
 Frame = -1

Query: 44   FLAACSSGDTDEVLKLLHRGADINYANVDGLTALHQACIDDNVDMVKFLVENGANIN-QP 102
            F A C  GD    L LL  GA+     VDG T L  AC +D  ++   L+ +GAN+N   
Sbjct: 1529 FHACCKRGDPRIALYLLRHGANKESRTVDGKTPLVVACKNDKAEVALLLIRSGANVNVSC 1350

Query: 103  DNEGWIPLHAAASCGYLDIAEFLIGQGAHVGAVNSEGDTPLDIXXXXXXXXXXQNEVNRQ 162
            D     P+H A     +++ + L+  GA V   N++G T L +             ++  
Sbjct: 1349 DITANTPVHFACQRPNIELLKRLVLHGADVDKPNAKGHTALHVASVRGFKQHVIYLLDFC 1170

Query: 163  GVDIEAARKEEERVMLRDARQWLNSGHISDVRHAKSGGTALHVAAAKGYTEVLKLLIQAG 222
              ++ AA  +                          G  ALH+A    + ++++LL+  G
Sbjct: 1169 DAEVNAATLK--------------------------GNNALHIACRGKHADLVELLLHKG 1068

Query: 223  YDVNIKDYDGWTPLHAA 239
             +   ++  GWTP ++A
Sbjct: 1067 ANPAQRNQRGWTPRNSA 1017

 Score = 46.6 bits (109), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 39/119 (32%), Positives = 54/119 (45%), Gaps = 3/119 (2%)
 Frame = -1

Query: 6    AKQKRN-EQLKRWIGSETDLEPPVVKRQKTKVKFDDGAVFLAACSSGDTDEVLKLL-HRG 63
            A Q+ N E LKR +    D++ P  K                A   G    V+ LL    
Sbjct: 1319 ACQRPNIELLKRLVLHGADVDKPNAKGHTA---------LHVASVRGFKQHVIYLLDFCD 1167

Query: 64   ADINYANVDGLTALHQACIDDNVDMVKFLVENGANINQPDNEGWIPLHAAASCG-YLDI 121
            A++N A + G  ALH AC   + D+V+ L+  GAN  Q +  GW P ++A  C   LDI
Sbjct: 1166 AEVNAATLKGNNALHIACRGKHADLVELLLHKGANPAQRNQRGWTPRNSAGRCXEVLDI 990
>25470
          Length = 400

 Score = 62.8 bits (151), Expect = 7e-10,   Method: Composition-based stats.
 Identities = 36/99 (36%), Positives = 54/99 (54%)
 Frame = -3

Query: 47  ACSSGDTDEVLKLLHRGADINYANVDGLTALHQACIDDNVDMVKFLVENGANINQPDNEG 106
           A   G  D V  LL  GA+++  +  GL  LH AC   + ++V+ L+ +GA+ N  DN  
Sbjct: 377 AAGFGRKDVVEHLLENGANVHARDDGGLIPLHNACSFGHAEVVQLLLRHGADPNARDNWN 198

Query: 107 WIPLHAAASCGYLDIAEFLIGQGAHVGAVNSEGDTPLDI 145
           + PLH AA  G +D+   L+ Q A     N++G T LD+
Sbjct: 197 YTPLHEAAIKGKIDVCIVLLQQCADPNIRNTDGKTALDL 81

 Score = 36.2 bits (82), Expect = 0.061,   Method: Composition-based stats.
 Identities = 26/77 (33%), Positives = 37/77 (48%), Gaps = 2/77 (2%)
 Frame = -3

Query: 39  DDGAV--FLAACSSGDTDEVLKLLHRGADINYANVDGLTALHQACIDDNVDMVKFLVENG 96
           DDG +     ACS G  + V  LL  GAD N  +    T LH+A I   +D+   L++  
Sbjct: 308 DDGGLIPLHNACSFGHAEVVQLLLRHGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQQC 129

Query: 97  ANINQPDNEGWIPLHAA 113
           A+ N  + +G   L  A
Sbjct: 128 ADPNIRNTDGKTALDLA 78
>11295
          Length = 1179

 Score = 62.4 bits (150), Expect = 9e-10,   Method: Compositional matrix adjust.
 Identities = 52/204 (25%), Positives = 86/204 (42%), Gaps = 4/204 (1%)
 Frame = +1

Query: 52  DTDEVLKLLHRGADINYANVDGLTALHQACIDDNVDMVKFLVE----NGANINQPDNEGW 107
           D   VL LL  GA I + +  GL+ALH ACI  N ++ + L++    +G  +N   N+  
Sbjct: 1   DRQTVLTLLQGGAQIYWTDHRGLSALHHACIGRNTEVAELLLDGWNGDGIAVNATSNDHV 180

Query: 108 IPLHAAASCGYLDIAEFLIGQGAHVGAVNSEGDTPLDIXXXXXXXXXXQNEVNRQGVDIE 167
             LH A      ++A  L+  GA+  A++  G TPL +          +  ++R  VD+ 
Sbjct: 181 TALHIACCLDDREMASLLLKYGAYAMALDVIGHTPLHVACWCGSEGVTRLLLDRSDVDVN 360

Query: 168 AARKEEERVMLRDARQWLNSGHISDVRHAKSGGTALHVAAAKGYTEVLKLLIQAGYDVNI 227
           A   +                          G   L +A+  G+  +++ L+    D  I
Sbjct: 361 ALDHD--------------------------GKXPLRLASECGFHYIIRQLLYHNADHTI 462

Query: 228 KDYDGWTPLHAAAHWGKEEACRIL 251
           +D   +TP H A  +     CR+L
Sbjct: 463 RDAAEFTPFHCAIRY-----CRVL 519

 Score = 43.9 bits (102), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 24/81 (29%), Positives = 45/81 (55%)
 Frame = +1

Query: 65  DINYANVDGLTALHQACIDDNVDMVKFLVENGANINQPDNEGWIPLHAAASCGYLDIAEF 124
           D+ ++  + L+    AC+  + +M+  L++ GA++N  D+  + PLH  +  G+L + + 
Sbjct: 550 DLIHSFYNDLSPTFMACLQCDKEMLSLLIKFGASVNCADHYHYTPLHYISRRGHLTMLQL 729

Query: 125 LIGQGAHVGAVNSEGDTPLDI 145
           L+   A    V+ EG TPL I
Sbjct: 730 LLQGKAEPNVVDDEGITPLYI 792

 Score = 36.2 bits (82), Expect = 0.064,   Method: Compositional matrix adjust.
 Identities = 21/53 (39%), Positives = 27/53 (50%)
 Frame = +1

Query: 201 TALHVAAAKGYTEVLKLLIQAGYDVNIKDYDGWTPLHAAAHWGKEEACRILVD 253
           TALH+A      E+  LL++ G      D  G TPLH A   G E   R+L+D
Sbjct: 181 TALHIACCLDDREMASLLLKYGAYAMALDVIGHTPLHVACWCGSEGVTRLLLD 339
>00540
          Length = 3034

 Score = 60.8 bits (146), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 54/191 (28%), Positives = 77/191 (40%)
 Frame = -2

Query: 62   RGADINYANVDGLTALHQACIDDNVDMVKFLVENGANINQPDNEGWIPLHAAASCGYLDI 121
            +GA++N       T L  AC D ++++V+FLVE+ A I   ++ G   L  A   G+LD+
Sbjct: 3003 KGAEVNQTTRSNSTPLRAACYDGHLEVVQFLVEHKAEIEIANSHGHTCLMIACYRGHLDV 2824

Query: 122  AEFLIGQGAHVGAVNSEGDTPLDIXXXXXXXXXXQNEVNRQGVDIEAARKEEERVMLRDA 181
             E+L+  GA                           +VNR+ V                 
Sbjct: 2823 VEYLLYLGA---------------------------QVNRRSV----------------- 2776

Query: 182  RQWLNSGHISDVRHAKSGGTALHVAAAKGYTEVLKLLIQAGYDVNIKDYDGWTPLHAAAH 241
                             G TALH +A  G   ++KLL+  G  +  KD  G TPL AAA 
Sbjct: 2775 ----------------KGNTALHDSAESGKLSIMKLLLSKGAKMA-KDAYGQTPLSAAAM 2647

Query: 242  WGKEEACRILV 252
             G EE  R L+
Sbjct: 2646 TGHEEIVRYLI 2614
>02114
          Length = 1072

 Score = 60.5 bits (145), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 64/238 (26%), Positives = 105/238 (44%), Gaps = 12/238 (5%)
 Frame = +1

Query: 47  ACSSGDTDEVLKLLHRGADINYANVDGLTALHQACIDDNVDMVKFLVENGANINQPDNEG 106
           AC+ G +  V  LL  G D+N  +    T++H +     +  ++ L++ GA  +  D  G
Sbjct: 322 ACAHGHSFCVQTLLRCGVDVNSVDKTSWTSVHVSSYHGRLGCLQMLIKWGARYDDIDTNG 501

Query: 107 WIPLHAAASCGYLDIAEFLI---GQGAH-VGAVNSEGDTPLDIXXXXXXXXXXQNEVNRQ 162
             P H AA  G+L   +FL+   G   H +GA N  G+TP D+                 
Sbjct: 502 NTPAHLAAMEGHLPCLKFLVSSEGCPEHTLGARNDHGETPRDL----------------- 630

Query: 163 GVDIEAARKEEERVMLRDARQWLNSGHISDVRH-------AKSGGTALHVAAAKGYTEVL 215
                A +  +E ++           +I  V+H       A++     H+AA  G  + L
Sbjct: 631 -----AQQFYKENIL----------EYIDHVQHEMDHPEQAENLAFPAHMAAYNGELDHL 765

Query: 216 KLLIQAG-YDVNIKDYDGWTPLHAAAHWGKEEACRILVDNLCDMETVNKVGQTAFDVA 272
           ++L++ G  ++N +D  G T  H AA  G     + LV+   D+E  N  G+TA D+A
Sbjct: 766 RILVENGVVNINERDDKGNTLAHRAAGQGHLNILQWLVEMGADVEISNGAGETARDIA 939

 Score = 50.8 bits (120), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 52/194 (26%), Positives = 79/194 (40%), Gaps = 8/194 (4%)
 Frame = +1

Query: 102 PDNEGWIPLHAAASCGYLDIAEFLIGQGAHVGAVNSEGDTPLDIXXXXXXXXXXQNEVNR 161
           P   GW P H AA  G     + L   G  + A ++ G TPL +          Q  + R
Sbjct: 190 PTPRGWTPAHIAAIRGQEGCIQALSNNGVSMSAKDTRGSTPLHLACAHGHSFCVQTLL-R 366

Query: 162 QGVDIEAARKEEERVMLRDARQWLNSGHISDVRHAKSGGTALHVAAAKGYTEVLKLLIQA 221
            GVD+ +           D   W                T++HV++  G    L++LI+ 
Sbjct: 367 CGVDVNSV----------DKTSW----------------TSVHVSSYHGRLGCLQMLIKW 468

Query: 222 GYDVNIKDYDGWTPLHAAAHWGKEEACRILVDN-LCDMETV---NKVGQTAFDVAD---- 273
           G   +  D +G TP H AA  G     + LV +  C   T+   N  G+T  D+A     
Sbjct: 469 GARYDDIDTNGNTPAHLAAMEGHLPCLKFLVSSEGCPEHTLGARNDHGETPRDLAQQFYK 648

Query: 274 EDILGYLEELQKKQ 287
           E+IL Y++ +Q + 
Sbjct: 649 ENILEYIDHVQHEM 690
>19166
          Length = 447

 Score = 58.5 bits (140), Expect = 1e-08,   Method: Composition-based stats.
 Identities = 45/164 (27%), Positives = 75/164 (45%)
 Frame = +1

Query: 59  LLHRGADINYANVDGLTALHQACIDDNVDMVKFLVENGANINQPDNEGWIPLHAAASCGY 118
           LL R  + N   ++G T LH AC  + + +V+ L++ GA+I+     G  PLH ++  G+
Sbjct: 16  LLDRKCEPNSRALNGFTPLHIACKKNRIKVVELLLKYGASIDATTESGLTPLHVSSFMGH 195

Query: 119 LDIAEFLIGQGAHVGAVNSEGDTPLDIXXXXXXXXXXQNEVNRQGVDIEAARKEEERVML 178
           ++I  +LI   A+       G+T L +                      AAR  +  ++ 
Sbjct: 196 MNIVIYLIQHNAYPDTPTVRGETSLHL----------------------AARANQTDII- 306

Query: 179 RDARQWLNSGHISDVRHAKSGGTALHVAAAKGYTEVLKLLIQAG 222
              R  L +G   D R A+   T LH+A+  G  + + LL+Q G
Sbjct: 307 ---RILLRNGAAVDAR-AREQQTPLHIASRLGNVDNVVLLLQHG 426

 Score = 50.8 bits (120), Expect = 2e-06,   Method: Composition-based stats.
 Identities = 34/99 (34%), Positives = 46/99 (46%)
 Frame = +1

Query: 47  ACSSGDTDEVLKLLHRGADINYANVDGLTALHQACIDDNVDMVKFLVENGANINQPDNEG 106
           AC       V  LL  GA I+     GLT LH +    ++++V +L+++ A  + P   G
Sbjct: 79  ACKKNRIKVVELLLKYGASIDATTESGLTPLHVSSFMGHMNIVIYLIQHNAYPDTPTVRG 258

Query: 107 WIPLHAAASCGYLDIAEFLIGQGAHVGAVNSEGDTPLDI 145
              LH AA     DI   L+  GA V A   E  TPL I
Sbjct: 259 ETSLHLAARANQTDIIRILLRNGAAVDARAREQQTPLHI 375

 Score = 43.5 bits (101), Expect = 4e-04,   Method: Composition-based stats.
 Identities = 26/84 (30%), Positives = 41/84 (48%)
 Frame = +1

Query: 51  GDTDEVLKLLHRGADINYANVDGLTALHQACIDDNVDMVKFLVENGANINQPDNEGWIPL 110
           G  + V+ L+   A  +   V G T+LH A   +  D+++ L+ NGA ++    E   PL
Sbjct: 190 GHMNIVIYLIQHNAYPDTPTVRGETSLHLAARANQTDIIRILLRNGAAVDARAREQQTPL 369

Query: 111 HAAASCGYLDIAEFLIGQGAHVGA 134
           H A+  G +D    L+  GA   A
Sbjct: 370 HIASRLGNVDNVVLLLQHGASADA 441

 Score = 41.2 bits (95), Expect = 0.002,   Method: Composition-based stats.
 Identities = 36/166 (21%), Positives = 62/166 (37%), Gaps = 1/166 (0%)
 Frame = +1

Query: 90  KFLVENGANINQPDNEGWIPLHAAASCGYLDIAEFLIGQGAHVGAVNSEGDTPLDIXXXX 149
           K L++     N     G+ PLH A     + + E L+  GA + A    G TPL +    
Sbjct: 10  KLLLDRKCEPNSRALNGFTPLHIACKKNRIKVVELLLKYGASIDATTESGLTPLHVSSFM 189

Query: 150 XXXXXXQNEVNRQGV-DIEAARKEEERVMLRDARQWLNSGHISDVRHAKSGGTALHVAAA 208
                    +      D    R                            G T+LH+AA 
Sbjct: 190 GHMNIVIYLIQHNAYPDTPTVR----------------------------GETSLHLAAR 285

Query: 209 KGYTEVLKLLIQAGYDVNIKDYDGWTPLHAAAHWGKEEACRILVDN 254
              T+++++L++ G  V+ +  +  TPLH A+  G  +   +L+ +
Sbjct: 286 ANQTDIIRILLRNGAAVDARAREQQTPLHIASRLGNVDNVVLLLQH 423

 Score = 37.7 bits (86), Expect = 0.022,   Method: Composition-based stats.
 Identities = 26/107 (24%), Positives = 52/107 (48%), Gaps = 1/107 (0%)
 Frame = +1

Query: 196 AKSGGTALHVAAAKGYTEVLKLLIQAGYDVNIKDYDGWTPLHAAAHWGKEEACRILVDNL 255
           A +G T LH+A  K   +V++LL++ G  ++     G TPLH ++  G       L+ + 
Sbjct: 49  ALNGFTPLHIACKKNRIKVVELLLKYGASIDATTESGLTPLHVSSFMGHMNIVIYLIQHN 228

Query: 256 CDMETVNKVGQTAFDVADE-DILGYLEELQKKQTLLHSEKRDKKSPL 301
              +T    G+T+  +A   +    +  L +    + +  R++++PL
Sbjct: 229 AYPDTPTVRGETSLHLAARANQTDIIRILLRNGAAVDARAREQQTPL 369

 Score = 34.3 bits (77), Expect = 0.23,   Method: Composition-based stats.
 Identities = 23/76 (30%), Positives = 37/76 (48%)
 Frame = +1

Query: 197 KSGGTALHVAAAKGYTEVLKLLIQAGYDVNIKDYDGWTPLHAAAHWGKEEACRILVDNLC 256
           +SG T LHV++  G+  ++  LIQ     +     G T LH AA   + +  RIL+ N  
Sbjct: 151 ESGLTPLHVSSFMGHMNIVIYLIQHNAYPDTPTVRGETSLHLAARANQTDIIRILLRNGA 330

Query: 257 DMETVNKVGQTAFDVA 272
            ++   +  QT   +A
Sbjct: 331 AVDARAREQQTPLHIA 378
>13462
          Length = 1388

 Score = 54.3 bits (129), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 56/207 (27%), Positives = 87/207 (42%), Gaps = 3/207 (1%)
 Frame = +3

Query: 49  SSGDTDEVLKLLHRGADINYANVDGLTALHQACIDDNVDMVKFLVENGANINQPDNEGWI 108
           S+G+   V  LL  GA  N  + DG TALH AC + NVD+V+ L+E G ++   D +   
Sbjct: 210 SNGNLGIVSMLLAYGAQPNVQDEDGNTALHLACSESNVDVVRLLLEWGGDVAVADIDNET 389

Query: 109 PLHAAASCGYLDIAEFLIGQGAHVGA-VNSEGDTPLDIXXXXXXXXXXQNEVNRQGVDIE 167
           PL  A     +++ + L+    H G+  N     PL+I                    + 
Sbjct: 390 PLVRACLANSVELVDLLL----HAGSDPNHSHGRPLEIV-------------------VR 500

Query: 168 AARKEEERVMLRDARQWLNSGHISDVRHAKSGGTALHVAAAKGYTEVLKLLIQAGYDVNI 227
           A   E  ++++    Q              +G T L  A+   Y +++K+L   G DVN 
Sbjct: 501 APSLESLKLLIGAGAQ-------------VTGNTYLSFASEHNYLDMMKVLHNYGVDVNG 641

Query: 228 KDYDGWTPLHAAA--HWGKEEACRILV 252
               G T LH A        +A R+L+
Sbjct: 642 TGRLGLTALHHACISQEATHDAVRLLL 722

 Score = 52.4 bits (124), Expect = 8e-07,   Method: Compositional matrix adjust.
 Identities = 57/206 (27%), Positives = 87/206 (42%), Gaps = 13/206 (6%)
 Frame = +3

Query: 47  ACSSGDTDEVLKLLHRGADINYANVDGLTALHQACIDDNVDMVKFLVENGANINQPDNEG 106
           ACS  + D V  LL  G D+  A++D  T L +AC+ ++V++V  L+  G++   P++  
Sbjct: 303 ACSESNVDVVRLLLEWGGDVAVADIDNETPLVRACLANSVELVDLLLHAGSD---PNHSH 473

Query: 107 WIPLHAAASCGYLDIAEFLIGQGAHVG-----AVNSEGDTPLDIXXXXXXXXXXQNEVNR 161
             PL        L+  + LIG GA V      +  SE +  LD+           N   R
Sbjct: 474 GRPLEIVVRAPSLESLKLLIGAGAQVTGNTYLSFASEHNY-LDMMKVLHNYGVDVNGTGR 650

Query: 162 QG--------VDIEAARKEEERVMLRDARQWLNSGHISDVRHAKSGGTALHVAAAKGYTE 213
            G        +  EA       ++L  +   L +G         +G T LH A       
Sbjct: 651 LGLTALHHACISQEATHDAVRLLLLWGSNPNLVTG---------TGDTPLHFACQTFAVS 803

Query: 214 VLKLLIQAGYDVNIKDYDGWTPLHAA 239
            ++LL+  G DVN  D    +PL AA
Sbjct: 804 KVRLLLMYGADVNQIDGTHTSPLIAA 881

 Score = 49.3 bits (116), Expect = 8e-06,   Method: Compositional matrix adjust.
 Identities = 35/106 (33%), Positives = 51/106 (48%), Gaps = 3/106 (2%)
 Frame = +3

Query: 41  GAVFLAACSSGDTDEVLKLLHR-GADINYANVDGLTALHQACIDDNV--DMVKFLVENGA 97
           G  +L+  S  +  +++K+LH  G D+N     GLTALH ACI      D V+ L+  G+
Sbjct: 555 GNTYLSFASEHNYLDMMKVLHNYGVDVNGTGRLGLTALHHACISQEATHDAVRLLLLWGS 734

Query: 98  NINQPDNEGWIPLHAAASCGYLDIAEFLIGQGAHVGAVNSEGDTPL 143
           N N     G  PLH A     +     L+  GA V  ++    +PL
Sbjct: 735 NPNLVTGTGDTPLHFACQTFAVSKVRLLLMYGADVNQIDGTHTSPL 872
>02055
          Length = 1740

 Score = 52.0 bits (123), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 54/187 (28%), Positives = 81/187 (43%), Gaps = 2/187 (1%)
 Frame = +3

Query: 55  EVLKLLHRGADINYANVDGLTALHQACIDDNVDMVKFLVENGANIN-QPDNEGWIPLHAA 113
           EV  L+  GAD+++ N+ G T LH A +  N + +  LV NGAN+N +       PLH A
Sbjct: 369 EVDDLIRCGADVDFCNMFGDTPLHIATVHANHEAMGALVRNGANVNARAKFLNSTPLHVA 548

Query: 114 ASC-GYLDIAEFLIGQGAHVGAVNSEGDTPLDIXXXXXXXXXXQNEVNRQGVDIEAARKE 172
               G  ++A  LI  GA +   ++ G TPL +                      A ++ 
Sbjct: 549 CRLRGQQEVA-LLIQLGARIDVNDATGTTPLQM----------------------ACKRA 659

Query: 173 EERVMLRDARQWLNSGHISDVRHAKSGGTALHVAAAKGYTEVLKLLIQAGYDVNIKDYDG 232
           +  V+       L     S VR  +        A  K    ++K+L +AG  VN   Y+G
Sbjct: 660 DPAVV-----NILLRSQPSIVR-TEDANKLFKYAIQKRQLHIVKMLCEAGVAVN---YEG 812

Query: 233 WTPLHAA 239
            TP+H A
Sbjct: 813 TTPVHIA 833

 Score = 39.7 bits (91), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 41/129 (31%), Positives = 49/129 (37%), Gaps = 1/129 (0%)
 Frame = +3

Query: 125 LIGQGAHVGAVNSEGDTPLDIXXXXXXXXXXQNEVNRQGVDIEAARKEEERVMLRDARQW 184
           LI  GA V   N  GDTPL I             V R G ++ A  K            +
Sbjct: 381 LIRCGADVDFCNMFGDTPLHIATVHANHEAMGALV-RNGANVNARAK------------F 521

Query: 185 LNSGHISDVRHAKSGGTALHVAA-AKGYTEVLKLLIQAGYDVNIKDYDGWTPLHAAAHWG 243
           LNS             T LHVA   +G  EV  LLIQ G  +++ D  G TPL  A    
Sbjct: 522 LNS-------------TPLHVACRLRGQQEV-ALLIQLGARIDVNDATGTTPLQMACKRA 659

Query: 244 KEEACRILV 252
                 IL+
Sbjct: 660 DPAVVNILL 686

 Score = 37.0 bits (84), Expect = 0.037,   Method: Compositional matrix adjust.
 Identities = 46/182 (25%), Positives = 63/182 (34%), Gaps = 33/182 (18%)
 Frame = +3

Query: 35  KVKFDDGAVFLAACSSGDTDEVLKLLHRGADINYANVDGLTALHQACI------------ 82
           + KF +      AC      EV  L+  GA I+  +  G T L  AC             
Sbjct: 510 RAKFLNSTPLHVACRLRGQQEVALLIQLGARIDVNDATGTTPLQMACKRADPAVVNILLR 689

Query: 83  ---------DDN-----------VDMVKFLVENGANINQPDNEGWIPLHAAASCGYLDIA 122
                    D N           + +VK L E G  +N    EG  P+H A      DIA
Sbjct: 690 SQPSIVRTEDANKLFKYAIQKRQLHIVKMLCEAGVAVNY---EGTTPVHIAMDNQAWDIA 860

Query: 123 EFLIGQGAH-VGAVNSEGDTPLDIXXXXXXXXXXQNEVNRQGVDIEAARKEEERVMLRDA 181
           +F I    H     +S+G TPL +           + +   G  I+      E  +LR  
Sbjct: 861 KFFITSNKHNFDGRDSKGRTPLCLALLSGADFHMVSFLLNVGYSIDQVDSNGETWLLRAG 1040

Query: 182 RQ 183
           RQ
Sbjct: 1041RQ 1046
>12417
          Length = 954

 Score = 49.7 bits (117), Expect = 6e-06,   Method: Compositional matrix adjust.
 Identities = 32/98 (32%), Positives = 50/98 (51%)
 Frame = +2

Query: 201 TALHVAAAKGYTEVLKLLIQAGYDVNIKDYDGWTPLHAAAHWGKEEACRILVDNLCDMET 260
            AL +AA +G  ++   LIQ G DVN     G TPLH A+  G      +L++   D++ 
Sbjct: 239 VALAMAANRGLDKMCSQLIQTGADVNSATEHGRTPLHXASAQGHGHIVDLLLEKGADIDA 418

Query: 261 VNKVGQTAFDVADEDILGYLEELQKKQTLLHSEKRDKK 298
            +  G TA  +AD+   G+ +   +   L H ++R KK
Sbjct: 419 EDDYGDTALSIADQ--FGF-KSCGRXLFLFHWQQRAKK 523

 Score = 44.3 bits (103), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 21/58 (36%), Positives = 33/58 (56%)
 Frame = +2

Query: 88  MVKFLVENGANINQPDNEGWIPLHAAASCGYLDIAEFLIGQGAHVGAVNSEGDTPLDI 145
           M   L++ GA++N     G  PLH A++ G+  I + L+ +GA + A +  GDT L I
Sbjct: 278 MCSQLIQTGADVNSATEHGRTPLHXASAQGHGHIVDLLLEKGADIDAEDDYGDTALSI 451
>15359
          Length = 780

 Score = 49.3 bits (116), Expect = 8e-06,   Method: Compositional matrix adjust.
 Identities = 29/86 (33%), Positives = 45/86 (52%), Gaps = 3/86 (3%)
 Frame = +1

Query: 44  FLAACSSGDTDEVLKLLHRGADINYAN--VDGLTALHQACIDDNVDMVKFLVEN-GANIN 100
           ++   ++ D  E+ +LL++ A +       +G TALH A      ++VK L    G  IN
Sbjct: 256 WMLVSATADYHEMFRLLNKNARLAKVKDIANGYTALHWAAKFGKPEVVKMLANKIGVEIN 435

Query: 101 QPDNEGWIPLHAAASCGYLDIAEFLI 126
           Q  + G+ PLH AA  G+ DI E L+
Sbjct: 436 QRSHGGYTPLHLAAIHGHEDIIELLV 513

 Score = 48.9 bits (115), Expect = 9e-06,   Method: Compositional matrix adjust.
 Identities = 32/90 (35%), Positives = 50/90 (55%), Gaps = 1/90 (1%)
 Frame = +1

Query: 164 VDIEAARKEEERVMLRDARQWLNSGHISDVRHAKSGGTALHVAAAKGYTEVLKLLI-QAG 222
           V   A   E  R++ ++AR       ++ V+   +G TALH AA  G  EV+K+L  + G
Sbjct: 265 VSATADYHEMFRLLNKNAR-------LAKVKDIANGYTALHWAAKFGKPEVVKMLANKIG 423

Query: 223 YDVNIKDYDGWTPLHAAAHWGKEEACRILV 252
            ++N + + G+TPLH AA  G E+   +LV
Sbjct: 424 VEINQRSHGGYTPLHLAAIHGHEDIIELLV 513
>21532
          Length = 460

 Score = 49.3 bits (116), Expect = 8e-06,   Method: Composition-based stats.
 Identities = 33/94 (35%), Positives = 43/94 (45%), Gaps = 7/94 (7%)
 Frame = -1

Query: 59  LLHRGADINYANVDGLTALHQACIDDNVDMVKFLVENGAN-------INQPDNEGWIPLH 111
           LL  GAD+N  +  G T    AC   N+  VK L+  G +       IN  DN    PLH
Sbjct: 439 LLSHGADVNIRDNTGCTPFANACCLGNLAAVKALLTPGESPSWSKPMINVRDNSQNTPLH 260

Query: 112 AAASCGYLDIAEFLIGQGAHVGAVNSEGDTPLDI 145
            A+  G+  I E L+   A + A N  G  PL +
Sbjct: 259 LASQEGHTAIVELLVEHKADLAAKNDSGHNPLSL 158

 Score = 36.2 bits (82), Expect = 0.066,   Method: Composition-based stats.
 Identities = 40/167 (23%), Positives = 66/167 (39%)
 Frame = -1

Query: 85  NVDMVKFLVENGANINQPDNEGWIPLHAAASCGYLDIAEFLIGQGAHVGAVNSEGDTPLD 144
           NV ++  L+ +GA++N  DN G  P  A A C         +G  A V A+ + G++P  
Sbjct: 460 NVPIINTLLSHGADVNIRDNTGCTPF-ANACC---------LGNLAAVKALLTPGESP-- 317

Query: 145 IXXXXXXXXXXQNEVNRQGVDIEAARKEEERVMLRDARQWLNSGHISDVRHAKSGGTALH 204
                                                  W  S  + +VR   S  T LH
Sbjct: 316 --------------------------------------SW--SKPMINVRD-NSQNTPLH 260

Query: 205 VAAAKGYTEVLKLLIQAGYDVNIKDYDGWTPLHAAAHWGKEEACRIL 251
           +A+ +G+T +++LL++   D+  K+  G  PL  A  +  E    +L
Sbjct: 259 LASQEGHTAIVELLVEHKADLAAKNDSGHNPLSLARQYKHENVVAVL 119
>30463
          Length = 412

 Score = 48.9 bits (115), Expect = 1e-05,   Method: Composition-based stats.
 Identities = 25/77 (32%), Positives = 42/77 (54%)
 Frame = -1

Query: 198 SGGTALHVAAAKGYTEVLKLLIQAGYDVNIKDYDGWTPLHAAAHWGKEEACRILVDNLCD 257
           +G TA H+AA  G++  + +L   G  ++ +  D  TPLH A+  G  E  + LV N   
Sbjct: 391 TGYTATHLAAMNGHSNAVMVLNIMGASIDCRTVDKQTPLHLASSAGHIECVKCLVANKAS 212

Query: 258 METVNKVGQTAFDVADE 274
           +   +   +TA+D+AD+
Sbjct: 211 LTAEDAFSRTAYDLADQ 161
>08473
          Length = 942

 Score = 48.9 bits (115), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 45/169 (26%), Positives = 73/169 (43%), Gaps = 4/169 (2%)
 Frame = -1

Query: 65  DINYANVDGLTALHQACIDDNVDMVKFLVENGANINQPDNEGWIPLHAAASCGYLDIAEF 124
           D++  + + +TALH AC   +   V  L++ GAN    +  G  PL  AA  G + I + 
Sbjct: 942 DVDMRDSNDMTALHHACAGLHYGCVHALLQGGANPTCMEMGGKTPLFYAAHRGEISICKL 763

Query: 125 LIGQGAHVGAVNSEGDTPLDIXXXXXXXXXXQNEVNRQGVDIEAARKEEERVMLRDARQW 184
           L+ +GA+V A +    TPL +            E NR+ V+    R        R+    
Sbjct: 762 LVDKGANVNAADKMLITPLMVAA---------REGNREAVEFLLKRGANPNTADRE---- 622

Query: 185 LNSGHISDVRHAKSGGTALHVAAAKGYTEVLKLL----IQAGYDVNIKD 229
              GH+           AL+ A A G+ E+ ++     +QA +D+   D
Sbjct: 621 ---GHL-----------ALYYAMAAGHPELREVFANAPLQASWDLRSPD 517

 Score = 45.8 bits (107), Expect = 8e-05,   Method: Compositional matrix adjust.
 Identities = 32/97 (32%), Positives = 44/97 (45%)
 Frame = -1

Query: 47  ACSSGDTDEVLKLLHRGADINYANVDGLTALHQACIDDNVDMVKFLVENGANINQPDNEG 106
           AC+      V  LL  GA+     + G T L  A     + + K LV+ GAN+N  D   
Sbjct: 897 ACAGLHYGCVHALLQGGANPTCMEMGGKTPLFYAAHRGEISICKLLVDKGANVNAADKML 718

Query: 107 WIPLHAAASCGYLDIAEFLIGQGAHVGAVNSEGDTPL 143
             PL  AA  G  +  EFL+ +GA+    + EG   L
Sbjct: 717 ITPLMVAAREGNREAVEFLLKRGANPNTADREGHLAL 607

 Score = 44.7 bits (104), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 25/72 (34%), Positives = 37/72 (51%)
 Frame = -1

Query: 201 TALHVAAAKGYTEVLKLLIQAGYDVNIKDYDGWTPLHAAAHWGKEEACRILVDNLCDMET 260
           TALH A A  +   +  L+Q G +    +  G TPL  AAH G+   C++LVD   ++  
Sbjct: 912 TALHHACAGLHYGCVHALLQGGANPTCMEMGGKTPLFYAAHRGEISICKLLVDKGANVNA 733

Query: 261 VNKVGQTAFDVA 272
            +K+  T   VA
Sbjct: 732 ADKMLITPLMVA 697

 Score = 39.3 bits (90), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 25/71 (35%), Positives = 33/71 (46%)
 Frame = -1

Query: 199 GGTALHVAAAKGYTEVLKLLIQAGYDVNIKDYDGWTPLHAAAHWGKEEACRILVDNLCDM 258
           G T L  AA +G   + KLL+  G +VN  D    TPL  AA  G  EA   L+    + 
Sbjct: 819 GKTPLFYAAHRGEISICKLLVDKGANVNAADKMLITPLMVAAREGNREAVEFLLKRGANP 640

Query: 259 ETVNKVGQTAF 269
            T ++ G  A 
Sbjct: 639 NTADREGHLAL 607
>15772
          Length = 1282

 Score = 48.1 bits (113), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 32/99 (32%), Positives = 46/99 (46%), Gaps = 3/99 (3%)
 Frame = -3

Query: 47   ACSSGDTDEVLKLLHRGA-DINYANVDG--LTALHQACIDDNVDMVKFLVENGANINQPD 103
            A S+GD D +   +  G  D+N  + D    TALH AC    V+ ++ L+++GA      
Sbjct: 1265 AASTGDYDALEDYVKSGIYDVNLKDPDAGNKTALHWACQKGFVECIRLLLDHGAKGTART 1086

Query: 104  NEGWIPLHAAASCGYLDIAEFLIGQGAHVGAVNSEGDTP 142
            + GW P H AA C  +     L      V   +  GDTP
Sbjct: 1085 DTGWTPAHCAAECNRVTALRALHAALVPVDLTDKYGDTP 969

 Score = 46.6 bits (109), Expect = 6e-05,   Method: Compositional matrix adjust.
 Identities = 26/72 (36%), Positives = 36/72 (50%)
 Frame = -3

Query: 201  TALHVAAAKGYTEVLKLLIQAGYDVNIKDYDGWTPLHAAAHWGKEEACRILVDNLCDMET 260
            TALH A  KG+ E ++LL+  G     +   GWTP H AA   +  A R L   L  ++ 
Sbjct: 1172 TALHWACQKGFVECIRLLLDHGAKGTARTDTGWTPAHCAAECNRVTALRALHAALVPVDL 993

Query: 261  VNKVGQTAFDVA 272
             +K G T   +A
Sbjct: 992  TDKYGDTPRRIA 957
>28113
          Length = 449

 Score = 46.2 bits (108), Expect = 6e-05,   Method: Compositional matrix adjust.
 Identities = 29/100 (29%), Positives = 49/100 (49%)
 Frame = -3

Query: 27  PVVKRQKTKVKFDDGAVFLAACSSGDTDEVLKLLHRGADINYANVDGLTALHQACIDDNV 86
           P   R   + ++ D     A+ + GD   V  LL+ G   +  +     A+H A    + 
Sbjct: 372 PDXPRNPVEPRWRDKYPLHASAAQGDVHHVQSLLNHGHHHSKKDSIAWAAIHYASWYGSA 193

Query: 87  DMVKFLVENGANINQPDNEGWIPLHAAASCGYLDIAEFLI 126
           D+V+ L++ G + N  ++E   PLH AA  G+ D+AE L+
Sbjct: 192 DVVEILLDAGCSPNLTNSELLTPLHIAAKKGFPDVAEHLV 73

 Score = 43.1 bits (100), Expect = 6e-04,   Method: Composition-based stats.
 Identities = 26/101 (25%), Positives = 47/101 (46%)
 Frame = -3

Query: 77  LHQACIDDNVDMVKFLVENGANINQPDNEGWIPLHAAASCGYLDIAEFLIGQGAHVGAVN 136
           LH +    +V  V+ L+ +G + ++ D+  W  +H A+  G  D+ E L+  G      N
Sbjct: 321 LHASAAQGDVHHVQSLLNHGHHHSKKDSIAWAAIHYASWYGSADVVEILLDAGCSPNLTN 142

Query: 137 SEGDTPLDIXXXXXXXXXXQNEVNRQGVDIEAARKEEERVM 177
           SE  TPL I          ++ V  + +D+    K+ +R +
Sbjct: 141 SELLTPLHIAAKKGFPDVAEHLVQAEAIDLNLRDKDGKRAI 19

 Score = 38.1 bits (87), Expect = 0.016,   Method: Composition-based stats.
 Identities = 29/91 (31%), Positives = 45/91 (49%), Gaps = 4/91 (4%)
 Frame = -3

Query: 185 LNSGHISDVRHAKSGG---TALHVAAAKGYTEVLKLLIQAGYDVNIKDYDGWTPLHAAAH 241
           LN GH     H+K       A+H A+  G  +V+++L+ AG   N+ + +  TPLH AA 
Sbjct: 273 LNHGH----HHSKKDSIAWAAIHYASWYGSADVVEILLDAGCSPNLTNSELLTPLHIAAK 106

Query: 242 WGKEEACRILVD-NLCDMETVNKVGQTAFDV 271
            G  +    LV     D+   +K G+ A D+
Sbjct: 105 KGFPDVAEHLVQAEAIDLNLRDKDGKRAIDI 13
>28691
          Length = 562

 Score = 45.8 bits (107), Expect = 8e-05,   Method: Compositional matrix adjust.
 Identities = 30/82 (36%), Positives = 44/82 (53%), Gaps = 5/82 (6%)
 Frame = +1

Query: 196 AKSGGTALHVAAAKGYTEVLKLLIQAGYDVNIKD---YDGWTPLHAAAHWGKE--EACRI 250
           +KSG  ALH+AA   + + + +L+QAG DVN K      G T LH A   G    ++   
Sbjct: 109 SKSGLPALHLAAKNKHVDCIPVLVQAGADVNAKGPSTIKGNTALHEAVSVGASNVDSVDA 288

Query: 251 LVDNLCDMETVNKVGQTAFDVA 272
           L+    D    N+ G+TA+D+A
Sbjct: 289 LLSCGADQNIXNEKGETAYDLA 354

 Score = 32.3 bits (72), Expect = 0.88,   Method: Compositional matrix adjust.
 Identities = 33/100 (33%), Positives = 49/100 (49%), Gaps = 7/100 (7%)
 Frame = +1

Query: 31  RQKTKVKFDDG--AVFLAACSSGDTDEVLKLLHRGADINY---ANVDGLTALHQACI--D 83
           RQ   V+   G  A+ LAA  +   D +  L+  GAD+N    + + G TALH+A     
Sbjct: 88  RQLASVESKSGLPALHLAA-KNKHVDCIPVLVQAGADVNAKGPSTIKGNTALHEAVSVGA 264

Query: 84  DNVDMVKFLVENGANINQPDNEGWIPLHAAASCGYLDIAE 123
            NVD V  L+  GA+ N  + +G      A+  GY +I +
Sbjct: 265 SNVDSVDALLSCGADQNIXNEKGETAYDLASKAGYENIVK 384
>17893
          Length = 453

 Score = 45.4 bits (106), Expect = 1e-04,   Method: Composition-based stats.
 Identities = 25/60 (41%), Positives = 36/60 (60%)
 Frame = -3

Query: 52  DTDEVLKLLHRGADINYANVDGLTALHQACIDDNVDMVKFLVENGANINQPDNEGWIPLH 111
           + D V  LL  GA IN  +  G T LH+A    +VD+ ++L+++G NI+QPD  G   LH
Sbjct: 184 NLDFVDSLLKNGASINIMDRTGQTLLHEAARAWHVDVTRWLLDHGINIDQPDYYGRTALH 5

 Score = 40.0 bits (92), Expect = 0.005,   Method: Composition-based stats.
 Identities = 21/61 (34%), Positives = 34/61 (55%)
 Frame = -3

Query: 85  NVDMVKFLVENGANINQPDNEGWIPLHAAASCGYLDIAEFLIGQGAHVGAVNSEGDTPLD 144
           N+D V  L++NGA+IN  D  G   LH AA   ++D+  +L+  G ++   +  G T L 
Sbjct: 184 NLDFVDSLLKNGASINIMDRTGQTLLHEAARAWHVDVTRWLLDHGINIDQPDYYGRTALH 5

Query: 145 I 145
           +
Sbjct: 4   V 2
>20036
          Length = 1849

 Score = 44.7 bits (104), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 29/94 (30%), Positives = 49/94 (52%), Gaps = 1/94 (1%)
 Frame = +3

Query: 182  RQWLNSGHISDVRHAKSGGTALHVAAAKGYTEVLKLLIQAGYDVNIKDYDGWTPLHAAAH 241
            RQ   +G I+     ++G TAL +A ++  T++++LL++ G D N +D+DG T L  A  
Sbjct: 1053 RQLFLAGDINACAE-QTGQTALMLATSQCRTDMVELLLETGADCNQQDFDGSTALMCACE 1229

Query: 242  WGKEEACRILVDN-LCDMETVNKVGQTAFDVADE 274
             G     ++L+    CD    +    TA  +A E
Sbjct: 1230 HGHTAIVQLLLAQPHCDATLTDNENSTALSIAME 1331

 Score = 43.9 bits (102), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 36/104 (34%), Positives = 50/104 (48%), Gaps = 3/104 (2%)
 Frame = +3

Query: 45   LAACSSGDTDEVLKLLHRGADIN-YANVDGLTALHQACIDDNVDMVKFLVENGANINQPD 103
            LA   + D  ++++ L    DIN  A   G TAL  A      DMV+ L+E GA+ NQ D
Sbjct: 1014 LAFIQNDDHRDIIRQLFLAGDINACAEQTGQTALMLATSQCRTDMVELLLETGADCNQQD 1193

Query: 104  NEGWIPLHAAASCGYLDIAEFLIGQGAHVGA--VNSEGDTPLDI 145
             +G   L  A   G+  I + L+ Q  H  A   ++E  T L I
Sbjct: 1194 FDGSTALMCACEHGHTAIVQLLLAQ-PHCDATLTDNENSTALSI 1322
>38834
          Length = 496

 Score = 43.1 bits (100), Expect = 6e-04,   Method: Composition-based stats.
 Identities = 18/63 (28%), Positives = 37/63 (58%)
 Frame = -1

Query: 205 VAAAKGYTEVLKLLIQAGYDVNIKDYDGWTPLHAAAHWGKEEACRILVDNLCDMETVNKV 264
           +A + G+ ++ ++L + G  +N+ + +G+TP H + ++ K +    LV    ++ TVN  
Sbjct: 496 IACSSGHLDIAEMLHRRGVQINVVNINGYTPXHLSVYFNKFDITHFLVKINAEINTVNNA 317

Query: 265 GQT 267
           GQT
Sbjct: 316 GQT 308

 Score = 42.7 bits (99), Expect = 8e-04,   Method: Composition-based stats.
 Identities = 20/64 (31%), Positives = 31/64 (48%)
 Frame = -1

Query: 80  ACIDDNVDMVKFLVENGANINQPDNEGWIPLHAAASCGYLDIAEFLIGQGAHVGAVNSEG 139
           AC   ++D+ + L   G  IN  +  G+ P H +      DI  FL+   A +  VN+ G
Sbjct: 493 ACSSGHLDIAEMLHRRGVQINVVNINGYTPXHLSVYFNKFDITHFLVKINAEINTVNNAG 314

Query: 140 DTPL 143
            TP+
Sbjct: 313 QTPV 302
>36917
          Length = 443

 Score = 42.4 bits (98), Expect = 0.001,   Method: Composition-based stats.
 Identities = 18/37 (48%), Positives = 25/37 (67%)
 Frame = -1

Query: 203 LHVAAAKGYTEVLKLLIQAGYDVNIKDYDGWTPLHAA 239
           LH+AAA GY EV + L+     V+ +D++ W PLHAA
Sbjct: 113 LHIAAANGYIEVAEFLLDNHVSVDRQDHESWQPLHAA 3

 Score = 36.2 bits (82), Expect = 0.065,   Method: Composition-based stats.
 Identities = 14/37 (37%), Positives = 26/37 (70%)
 Frame = -1

Query: 77  LHQACIDDNVDMVKFLVENGANINQPDNEGWIPLHAA 113
           LH A  +  +++ +FL++N  ++++ D+E W PLHAA
Sbjct: 113 LHIAAANGYIEVAEFLLDNHVSVDRQDHESWQPLHAA 3
>25464
          Length = 440

 Score = 40.4 bits (93), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 30/85 (35%), Positives = 45/85 (52%), Gaps = 5/85 (5%)
 Frame = -3

Query: 64  ADINYANVDGLTALHQACIDDNVDMVKFLV-ENGANINQPDNEGWIPLHAAASCGYLDI- 121
           A +N  +  G TAL  AC++   D+V+ ++ E+  +IN+PDN+G  P+H AA     +I 
Sbjct: 438 AYLNVRDSMGRTALSYACLNGRQDIVRCILKEDVLDINEPDNDGNTPIHHAAISANPNIV 259

Query: 122 ---AEFLIGQGAHVGAVNSEGDTPL 143
              AE     G +    N  G TPL
Sbjct: 258 RMLAEAFYKFGLNPDKRNKLGYTPL 184

 Score = 32.0 bits (71), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 23/79 (29%), Positives = 38/79 (48%), Gaps = 5/79 (6%)
 Frame = -3

Query: 199 GGTALHVAAAKGYTEVLKLLIQAG-YDVNIKDYDGWTPLHAAAHWGKEEACRILVDNL-- 255
           G TAL  A   G  ++++ +++    D+N  D DG TP+H AA        R+L +    
Sbjct: 411 GRTALSYACLNGRQDIVRCILKEDVLDINEPDNDGNTPIHHAAISANPNIVRMLAEAFYK 232

Query: 256 --CDMETVNKVGQTAFDVA 272
              + +  NK+G T   +A
Sbjct: 231 FGLNPDKRNKLGYTPLLLA 175
>27108
          Length = 449

 Score = 40.4 bits (93), Expect = 0.004,   Method: Composition-based stats.
 Identities = 25/55 (45%), Positives = 30/55 (54%), Gaps = 1/55 (1%)
 Frame = -3

Query: 199 GGTALHVAAAKGYTEVLK-LLIQAGYDVNIKDYDGWTPLHAAAHWGKEEACRILV 252
           G T L  AA K    +LK LL   G D+N +DY GWT LH A + G  E  R L+
Sbjct: 387 GETMLIRAAIKNNLSLLKHLLTVPGVDINSQDYAGWTALHEACNHGHLECARALL 223

 Score = 32.0 bits (71), Expect = 1.3,   Method: Composition-based stats.
 Identities = 15/37 (40%), Positives = 25/37 (67%)
 Frame = -3

Query: 62  RGADINYANVDGLTALHQACIDDNVDMVKFLVENGAN 98
           R  D++ AN +G+TALH A   ++V +VK L++ G +
Sbjct: 159 RKVDMHLANQEGITALHDAVSMNHVSVVKLLLKYGGS 49

 Score = 31.2 bits (69), Expect = 2.0,   Method: Composition-based stats.
 Identities = 26/105 (24%), Positives = 46/105 (43%), Gaps = 22/105 (20%)
 Frame = -3

Query: 63  GADINYANVDGLTALHQACIDDNVDMVKFLV------------ENGAN--------INQP 102
           G DIN  +  G TALH+AC   +++  + L+            ++G N        ++  
Sbjct: 315 GVDINSQDYAGWTALHEACNHGHLECARALLKFVPSATLDSFFQSGKNRGKVRKVDMHLA 136

Query: 103 DNEGWIPLHAAASCGYLDIAEFLIGQGAH--VGAVNSEGDTPLDI 145
           + EG   LH A S  ++ + + L+  G    +      GDT +D+
Sbjct: 135 NQEGITALHDAVSMNHVSVVKLLLKYGGSSLLKDKTVSGDTVMDL 1
>22305
          Length = 426

 Score = 40.0 bits (92), Expect = 0.004,   Method: Composition-based stats.
 Identities = 23/66 (34%), Positives = 35/66 (53%)
 Frame = -3

Query: 54  DEVLKLLHRGADINYANVDGLTALHQACIDDNVDMVKFLVENGANINQPDNEGWIPLHAA 113
           D    LL RG   N  N  G+  LH+A   +NV++ + L++ GA+ N P     +PL  A
Sbjct: 343 DITTALLERGCSANERNHWGILPLHEALCWENVEVGRVLLQYGADPNVPCETNVVPLTFA 164

Query: 114 ASCGYL 119
           A  G++
Sbjct: 163 ARTGHI 146
>34789
          Length = 1249

 Score = 40.0 bits (92), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 26/80 (32%), Positives = 41/80 (51%)
 Frame = +3

Query: 66  INYANVDGLTALHQACIDDNVDMVKFLVENGANINQPDNEGWIPLHAAASCGYLDIAEFL 125
           +N    DG TAL  A  D NV++V +L++NGAN +     G   LHAA     + + +  
Sbjct: 57  LNQMGSDGSTALFMAVYDGNVELVDYLLKNGANPHFSSQHGNF-LHAAVLSQSVPLIQRA 233

Query: 126 IGQGAHVGAVNSEGDTPLDI 145
           +  G  +   N  G++PL +
Sbjct: 234 LDLGCDINEHNMFGNSPLTL 293

 Score = 32.3 bits (72), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 18/68 (26%), Positives = 36/68 (52%)
 Frame = +3

Query: 195 HAKSGGTALHVAAAKGYTEVLKLLIQAGYDVNIKDYDGWTPLHAAAHWGKEEACRILVDN 254
           H   G + L + +     E  ++L++ G D+N +D    TPL A+ ++G E   R+L+ +
Sbjct: 261 HNMFGNSPLTLVSRLDLPEACRMLVEHGADLNSRDRYRETPLLASVYFGCELNARLLIQH 440

Query: 255 LCDMETVN 262
              ++ V+
Sbjct: 441 GASLDLVD 464

 Score = 31.2 bits (69), Expect = 2.0,   Method: Compositional matrix adjust.
 Identities = 30/96 (31%), Positives = 42/96 (43%)
 Frame = +3

Query: 41  GAVFLAACSSGDTDEVLKLLHRGADINYANVDGLTALHQACIDDNVDMVKFLVENGANIN 100
           G    AA  S     + + L  G DIN  N+ G + L      D  +  + LVE+GA++N
Sbjct: 177 GNFLHAAVLSQSVPLIQRALDLGCDINEHNMFGNSPLTLVSRLDLPEACRMLVEHGADLN 356

Query: 101 QPDNEGWIPLHAAASCGYLDIAEFLIGQGAHVGAVN 136
             D     PL A+   G    A  LI  GA +  V+
Sbjct: 357 SRDRYRETPLLASVYFGCELNARLLIQHGASLDLVD 464

 Score = 30.8 bits (68), Expect = 2.7,   Method: Compositional matrix adjust.
 Identities = 18/68 (26%), Positives = 34/68 (50%)
 Frame = +3

Query: 200 GTALHVAAAKGYTEVLKLLIQAGYDVNIKDYDGWTPLHAAAHWGKEEACRILVDNLCDME 259
           G  LH A       +++  +  G D+N  +  G +PL   +     EACR+LV++  D+ 
Sbjct: 177 GNFLHAAVLSQSVPLIQRALDLGCDINEHNMFGNSPLTLVSRLDLPEACRMLVEHGADLN 356

Query: 260 TVNKVGQT 267
           + ++  +T
Sbjct: 357 SRDRYRET 380
>16561
          Length = 2029

 Score = 40.0 bits (92), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 34/105 (32%), Positives = 49/105 (46%), Gaps = 3/105 (2%)
 Frame = -3

Query: 44   FLAACSSGDTDEVLKLLHRGADINYANVDGLTALHQACIDDNV---DMVKFLVENGANIN 100
             L A S G +  +  L+H  ADIN ++ DG T LH A +   V   D  + L    + + 
Sbjct: 1499 LLLAVSQGHSSLIELLVHAQADINVSDEDGDTCLHLALMRQTVATEDSSRMLDSIRSQLG 1320

Query: 101  QPDNEGWIPLHAAASCGYLDIAEFLIGQGAHVGAVNSEGDTPLDI 145
              ++E       AA      IA +L  QGA + A N +G  PLD+
Sbjct: 1319 MGEDEAQT---GAA------IACYLAQQGASLTACNQQGKXPLDV 1212

 Score = 33.5 bits (75), Expect = 0.43,   Method: Compositional matrix adjust.
 Identities = 17/41 (41%), Positives = 24/41 (58%)
 Frame = -3

Query: 199  GGTALHVAAAKGYTEVLKLLIQAGYDVNIKDYDGWTPLHAA 239
            G + LHVA  K + + + +L+  G DVN +D  G T LH A
Sbjct: 1913 GCSTLHVAVNKQHIKCVHVLLNXGCDVNXQDAYGDTALHDA 1791
>35952
          Length = 1624

 Score = 39.3 bits (90), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 31/86 (36%), Positives = 42/86 (48%), Gaps = 1/86 (1%)
 Frame = -1

Query: 192 DVRHAKSGGTALHVAAAKGYTEVLK-LLIQAGYDVNIKDYDGWTPLHAAAHWGKEEACRI 250
           D+   KSG TALH A       V   LL++A  DVN + +DG TPLH A        CR 
Sbjct: 994 DLPDGKSGRTALHHAVELDDLPVAGFLLMEANADVNARCFDGNTPLHVA-------CCRG 836

Query: 251 LVDNLCDMETVNKVGQTAFDVADEDI 276
           L+  +  + T   +     DV +E+I
Sbjct: 835 LIGMVALLMTAGAL----TDVENEEI 770

 Score = 37.4 bits (85), Expect = 0.032,   Method: Compositional matrix adjust.
 Identities = 27/77 (35%), Positives = 37/77 (48%), Gaps = 7/77 (9%)
 Frame = -1

Query: 69   ANVD------GLTALHQACIDDNVDMVKFLV-ENGANINQPDNEGWIPLHAAASCGYLDI 121
            ANVD      G TALH A   D++ +  FL+ E  A++N    +G  PLH A   G + +
Sbjct: 1003 ANVDLPDGKSGRTALHHAVELDDLPVAGFLLMEANADVNARCFDGNTPLHVACCRGLIGM 824

Query: 122  AEFLIGQGAHVGAVNSE 138
               L+  GA     N E
Sbjct: 823  VALLMTAGALTDVENEE 773
>20792
          Length = 441

 Score = 38.9 bits (89), Expect = 0.010,   Method: Composition-based stats.
 Identities = 20/75 (26%), Positives = 33/75 (44%)
 Frame = +2

Query: 65  DINYANVDGLTALHQACIDDNVDMVKFLVENGANINQPDNEGWIPLHAAASCGYLDIAEF 124
           D+   N +G   LH+      +D + FL++ G  ++      W PL  A +   L +   
Sbjct: 53  DLQIGNFEGKKPLHETAQFGQLDCMNFLLQRGVQVDCLKRADWTPLMLACTKCQLPVISL 232

Query: 125 LIGQGAHVGAVNSEG 139
           L+  GA    VN +G
Sbjct: 233 LLKHGADPALVNKDG 277

 Score = 34.3 bits (77), Expect = 0.24,   Method: Composition-based stats.
 Identities = 22/74 (29%), Positives = 32/74 (43%)
 Frame = +2

Query: 199 GGTALHVAAAKGYTEVLKLLIQAGYDVNIKDYDGWTPLHAAAHWGKEEACRILVDNLCDM 258
           G   LH  A  G  + +  L+Q G  V+      WTPL  A    +     +L+ +  D 
Sbjct: 77  GKKPLHETAQFGQLDCMNFLLQRGVQVDCLKRADWTPLMLACTKCQLPVISLLLKHGADP 256

Query: 259 ETVNKVGQTAFDVA 272
             VNK G  +F +A
Sbjct: 257 ALVNKDGWNSFHIA 298

 Score = 31.2 bits (69), Expect = 2.5,   Method: Composition-based stats.
 Identities = 16/39 (41%), Positives = 19/39 (48%)
 Frame = +2

Query: 105 EGWIPLHAAASCGYLDIAEFLIGQGAHVGAVNSEGDTPL 143
           EG  PLH  A  G LD   FL+ +G  V  +     TPL
Sbjct: 74  EGKKPLHETAQFGQLDCMNFLLQRGVQVDCLKRADWTPL 190

 Score = 29.3 bits (64), Expect = 7.8,   Method: Composition-based stats.
 Identities = 17/55 (30%), Positives = 26/55 (47%)
 Frame = +2

Query: 36  VKFDDGAVFLAACSSGDTDEVLKLLHRGADINYANVDGLTALHQACIDDNVDMVK 90
           +K  D    + AC+      +  LL  GAD    N DG  + H A  + +VD++K
Sbjct: 164 LKRADWTPLMLACTKCQLPVISLLLKHGADPALVNKDGWNSFHIAAREGHVDILK 328
>27067
          Length = 409

 Score = 38.1 bits (87), Expect = 0.020,   Method: Composition-based stats.
 Identities = 36/120 (30%), Positives = 53/120 (44%), Gaps = 9/120 (7%)
 Frame = +1

Query: 5   DAKQKRNEQLKRWIGSETDLEPPVVK-RQKTKVKFDDGAVFLAACSSGDTDEVLKLLHRG 63
           +A +  N  + R++ +   LE   V   QKT V        + A S G  + +  LL  G
Sbjct: 43  EAIKVNNTDILRYLLTVPGLECNAVNASQKTPV--------MEAASRGRIECLTMLLDHG 198

Query: 64  ADINYANVDGLTALHQ---AC-----IDDNVDMVKFLVENGANINQPDNEGWIPLHAAAS 115
            +    N+ G TA+H    +C     I+D V  +  + + G NIN  D  G  PLH A S
Sbjct: 199 CNTEGENIRGKTAMHHCLLSCGGFVEIEDMVTCMDLVYKAGGNINAQDWFGTSPLHLAIS 378
>21751
          Length = 643

 Score = 37.7 bits (86), Expect = 0.025,   Method: Composition-based stats.
 Identities = 18/46 (39%), Positives = 30/46 (65%), Gaps = 1/46 (2%)
 Frame = +3

Query: 59  LLHRGADINYANVDGL-TALHQACIDDNVDMVKFLVENGANINQPD 103
           LL  G D+N    D L + +HQA  + ++DM+  L+E GA++N+P+
Sbjct: 135 LLEHGEDVNQTFNDSLESPIHQAVRNLDLDMINLLIEFGADLNRPN 272
>11861
          Length = 586

 Score = 36.2 bits (82), Expect = 0.074,   Method: Composition-based stats.
 Identities = 28/91 (30%), Positives = 41/91 (45%), Gaps = 1/91 (1%)
 Frame = -1

Query: 56  VLKLLHRGADINYANVDGLTALHQACIDDNVDMVKFLVENGANINQPDNEGWIPLHAAAS 115
           V +LL RGAD +         +  A      D+VK L+ N A+I +PD  G  PL    +
Sbjct: 331 VKELLIRGADASATESSRKPLVKLAVRKKQWDVVKALILNHADIYRPDKMGQTPLSTLIT 152

Query: 116 CGYLDIAEFLIGQ-GAHVGAVNSEGDTPLDI 145
              +++  F I       GAV+  G T L +
Sbjct: 151 AANMEMIHFAIQHCPGMAGAVDMSGQTILHV 59
>08755
          Length = 885

 Score = 35.0 bits (79), Expect = 0.15,   Method: Composition-based stats.
 Identities = 24/69 (34%), Positives = 36/69 (52%), Gaps = 1/69 (1%)
 Frame = +3

Query: 72  DGLTALHQACIDDNVDMVKFLVENGANIN-QPDNEGWIPLHAAASCGYLDIAEFLIGQGA 130
           DG +ALH A    N +++  L+ +GAN + + D  G  PL  AAS       + LIG G+
Sbjct: 651 DGQSALHIAV--KNPEVISVLLAHGANPDVKVDGSGVTPLMLAASMTKTAALQILIGAGS 824

Query: 131 HVGAVNSEG 139
            +   N+ G
Sbjct: 825 SIDCRNNAG 851
>02050
          Length = 2483

 Score = 34.7 bits (78), Expect = 0.17,   Method: Compositional matrix adjust.
 Identities = 30/90 (33%), Positives = 42/90 (46%), Gaps = 13/90 (14%)
 Frame = -1

Query: 179  RDARQWLN------------SGHI-SDVRHAKSGGTALHVAAAKGYTEVLKLLIQAGYDV 225
            RDARQ L             S H+ S V  A++   A+ VAA     +V  +    G+D 
Sbjct: 1850 RDARQLLTKARDMGLNVVGISFHVGSGVAEAEAFSAAVEVAA-----QVFDVGQTLGFDF 1686

Query: 226  NIKDYDGWTPLHAAAHWGKEEACRILVDNL 255
            ++ D  G  P HAAA    EE  R+L ++L
Sbjct: 1685 DLLDIGGGFPGHAAAPITFEEIARVLNESL 1596
>02351
          Length = 939

 Score = 34.3 bits (77), Expect = 0.25,   Method: Composition-based stats.
 Identities = 25/67 (37%), Positives = 33/67 (49%), Gaps = 2/67 (2%)
 Frame = +3

Query: 65  DIN--YANVDGLTALHQACIDDNVDMVKFLVENGANINQPDNEGWIPLHAAASCGYLDIA 122
           DIN  Y   DG TALH A    NV  V+ L+   AN+   D+EG   L  A + G ++  
Sbjct: 438 DINSPYGKDDGRTALHIAAALGNVVYVQLLLWYCANVKVVDHEGRNALWYARTSGSVECT 617

Query: 123 EFLIGQG 129
           + L   G
Sbjct: 618 DLLAAAG 638

 Score = 30.8 bits (68), Expect = 2.9,   Method: Composition-based stats.
 Identities = 20/58 (34%), Positives = 29/58 (50%)
 Frame = +3

Query: 199 GGTALHVAAAKGYTEVLKLLIQAGYDVNIKDYDGWTPLHAAAHWGKEEACRILVDNLC 256
           G TALH+AAA G    ++LL+    +V + D++G   L  A   G  E   +L    C
Sbjct: 468 GRTALHIAAALGNVVYVQLLLWYCANVKVVDHEGRNALWYARTSGSVECTDLLAAAGC 641
>05396
          Length = 1865

 Score = 34.3 bits (77), Expect = 0.27,   Method: Compositional matrix adjust.
 Identities = 21/54 (38%), Positives = 32/54 (59%), Gaps = 1/54 (1%)
 Frame = +3

Query: 199  GGTALHVAAAKGYTEVLKLLI-QAGYDVNIKDYDGWTPLHAAAHWGKEEACRIL 251
            G TALHVA+A+G  +V++ L+ +      + D  G+TPL  A  + K EA  +L
Sbjct: 1383 GRTALHVASAEGQLQVVEFLLDRCKCSPFLVDRWGFTPLDDAVRFEKHEAAELL 1544

 Score = 33.5 bits (75), Expect = 0.48,   Method: Compositional matrix adjust.
 Identities = 19/51 (37%), Positives = 30/51 (58%), Gaps = 1/51 (1%)
 Frame = +3

Query: 95   NGANINQPDNEGWIPLHAAASCGYLDIAEFLIGQG-AHVGAVNSEGDTPLD 144
            +G +++QPD +G   LH A++ G L + EFL+ +       V+  G TPLD
Sbjct: 1350 SGMDMSQPDYDGRTALHVASAEGQLQVVEFLLDRCKCSPFLVDRWGFTPLD 1502
>30978
          Length = 566

 Score = 33.1 bits (74), Expect = 0.57,   Method: Compositional matrix adjust.
 Identities = 20/57 (35%), Positives = 35/57 (61%), Gaps = 1/57 (1%)
 Frame = -2

Query: 197 KSGGTALHVAAAKGYTEVLKLLI-QAGYDVNIKDYDGWTPLHAAAHWGKEEACRILV 252
           K+G T LH A   G+ + L++L+ +   +VN+++  G T LH+AA     EA ++L+
Sbjct: 478 KAGSTPLHWAGHGGHMDCLQVLLSEPKCEVNVQNKLGDTALHSAAWKNHVEAVKMLL 308

 Score = 30.0 bits (66), Expect = 5.1,   Method: Compositional matrix adjust.
 Identities = 24/78 (30%), Positives = 41/78 (52%), Gaps = 6/78 (7%)
 Frame = -2

Query: 67  NYANVDGL-----TALHQACIDDNVDMVKFLV-ENGANINQPDNEGWIPLHAAASCGYLD 120
           N  +V+GL     T LH A    ++D ++ L+ E    +N  +  G   LH+AA   +++
Sbjct: 505 NRVSVNGLDKAGSTPLHWAGHGGHMDCLQVLLSEPKCEVNVQNKLGDTALHSAAWKNHVE 326

Query: 121 IAEFLIGQGAHVGAVNSE 138
             + L+G+GA V   N+E
Sbjct: 325 AVKMLLGKGARVDLRNNE 272
>09214
          Length = 2116

 Score = 32.7 bits (73), Expect = 0.71,   Method: Compositional matrix adjust.
 Identities = 18/48 (37%), Positives = 30/48 (62%), Gaps = 1/48 (2%)
 Frame = -3

Query: 62   RGADINYAN-VDGLTALHQACIDDNVDMVKFLVENGANINQPDNEGWI 108
            +  D+N  N ++G TALH     D+  +V++L+ +GA+ N  DN+G I
Sbjct: 1646 KNVDVNAQNKMNGRTALHWGAKRDHQTVVQYLLSHGADKNAVDNDGKI 1503
>28345
          Length = 365

 Score = 32.7 bits (73), Expect = 0.76,   Method: Composition-based stats.
 Identities = 18/55 (32%), Positives = 29/55 (52%), Gaps = 1/55 (1%)
 Frame = +3

Query: 213 EVLKLLIQAGYDVNIKDYDGWTPLHAAAHWGKEEACRILVDN-LCDMETVNKVGQ 266
           EV+ LL+  G DVN +D+DG  PL  A      +   +L+    CD+  ++ V +
Sbjct: 9   EVVSLLLDLGCDVNGEDFDGGFPLSLALRKHLSQXALLLISQPACDLNVLDPVSK 173
>30217
          Length = 412

 Score = 32.7 bits (73), Expect = 0.77,   Method: Composition-based stats.
 Identities = 20/57 (35%), Positives = 30/57 (52%), Gaps = 3/57 (5%)
 Frame = -3

Query: 199 GGTALHVAAAKGYTEVLKLLIQAGYD---VNIKDYDGWTPLHAAAHWGKEEACRILV 252
           G T LH+A   GY +V+  LI+       +NI++    TPLH AA   +    R+L+
Sbjct: 206 GDTPLHLACISGYVDVVAALIRMAPHPCLLNIQNDVAQTPLHLAALTAQPTILRMLL 36

 Score = 31.6 bits (70), Expect = 1.5,   Method: Composition-based stats.
 Identities = 17/48 (35%), Positives = 25/48 (52%), Gaps = 3/48 (6%)
 Frame = -3

Query: 101 QPDNEGWIPLHAAASCGYLDIAEFLIGQGAHVGAVNSEGD---TPLDI 145
           Q +++G  PLH A   GY+D+   LI    H   +N + D   TPL +
Sbjct: 221 QQNDDGDTPLHLACISGYVDVVAALIRMAPHPCLLNIQNDVAQTPLHL 78
>20988
          Length = 530

 Score = 31.6 bits (70), Expect = 1.6,   Method: Composition-based stats.
 Identities = 15/40 (37%), Positives = 22/40 (55%), Gaps = 1/40 (2%)
 Frame = -1

Query: 43  VFLAACSSGDTDEVLKLLHRGADINYAN-VDGLTALHQAC 81
           +   AC +G  D + K++ RG D+N      G +ALH AC
Sbjct: 281 IMFGACITGHVDVIRKVVDRGVDVNAPGPFVGRSALHVAC 162
>33144
          Length = 272

 Score = 31.6 bits (70), Expect = 1.6,   Method: Composition-based stats.
 Identities = 20/67 (29%), Positives = 32/67 (47%), Gaps = 1/67 (1%)
 Frame = +3

Query: 77  LHQACIDDNVDMVKFLVENG-ANINQPDNEGWIPLHAAASCGYLDIAEFLIGQGAHVGAV 135
           LH A ++    +   LV+ G   +N  D     PLH A     L I + L+G+ A+    
Sbjct: 24  LHLAAMNGRTAIAGVLVKKGEVAVNVVDKHKRTPLHYAVQTCELTIIDLLLGRDANPNIQ 203

Query: 136 NSEGDTP 142
           + +G+TP
Sbjct: 204 DVDGNTP 224
>34070
          Length = 516

 Score = 31.2 bits (69), Expect = 2.2,   Method: Compositional matrix adjust.
 Identities = 16/39 (41%), Positives = 24/39 (61%)
 Frame = +1

Query: 930 DFKKLYEQILAENEKLKAQLHDTNMELTDLKLQLEKATQ 968
           D+KKLYE+   EN +LK +L     EL D K +L ++ +
Sbjct: 190 DYKKLYEEEKVENGRLKKELDQCKKELLDAKAELXQSPK 306
>26054
          Length = 437

 Score = 29.6 bits (65), Expect = 6.6,   Method: Composition-based stats.
 Identities = 23/66 (34%), Positives = 32/66 (48%)
 Frame = -3

Query: 187 SGHISDVRHAKSGGTALHVAAAKGYTEVLKLLIQAGYDVNIKDYDGWTPLHAAAHWGKEE 246
           S   + V++A    TA  +AA +     L+LL +AG   +  D    TPL  A   G EE
Sbjct: 213 SPKTTRVKYAHKZVTAGMMAAIRNRVVYLRLLGEAGERFDGLDAMDMTPLMLALCHGNEE 34

Query: 247 ACRILV 252
           A R L+
Sbjct: 33  AARYLL 16
>20884
          Length = 712

 Score = 29.3 bits (64), Expect = 9.0,   Method: Composition-based stats.
 Identities = 12/21 (57%), Positives = 17/21 (80%)
 Frame = +1

Query: 199 GGTALHVAAAKGYTEVLKLLI 219
           G TALH+A  +G TE++KLL+
Sbjct: 397 GNTALHIACREGMTEMVKLLL 459
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|19527358|ref|NP_598890.1| nuclear matrix protein SNEV
[Mus musculus]
         (504 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

16199                                                                 172   3e-43
30256                                                                  78   9e-15
13335                                                                  75   8e-14
00561                                                                  73   3e-13
17598                                                                  72   5e-13
02147                                                                  72   7e-13
19949                                                                  71   1e-12
03395                                                                  70   3e-12
02090                                                                  67   2e-11
01327                                                                  65   4e-11
17266                                                                  65   8e-11
12806                                                                  63   3e-10
17602                                                                  60   3e-09
03387                                                                  58   1e-08
03156                                                                  57   2e-08
14500                                                                  48   3e-08
15118                                                                  54   1e-07
19498                                                                  54   1e-07
12574                                                                  52   5e-07
21105                                                                  52   6e-07
27465                                                                  51   8e-07
19140                                                                  51   1e-06
37180                                                                  51   1e-06
00825                                                                  50   2e-06
15780                                                                  49   4e-06
12960                                                                  49   5e-06
20662                                                                  49   7e-06
01768                                                                  48   1e-05
16105                                                                  47   2e-05
13278                                                                  47   2e-05
19863                                                                  46   3e-05
18981                                                                  45   5e-05
31054                                                                  45   7e-05
26939                                                                  45   8e-05
02960                                                                  44   1e-04
27806                                                                  44   1e-04
31384                                                                  44   2e-04
15745                                                                  44   2e-04
01462                                                                  42   4e-04
01249                                                                  42   6e-04
14555                                                                  37   0.001
27270                                                                  38   0.009
21921                                                                  38   0.012
26107                                                                  37   0.013
10162                                                                  37   0.024
35607                                                                  36   0.029
11493                                                                  36   0.044
10264                                                                  35   0.049
04358                                                                  35   0.049
31864                                                                  35   0.055
30295                                                                  35   0.067
01598                                                                  35   0.068
02948                                                                  35   0.070
21960                                                                  35   0.074
36111                                                                  35   0.076
15972                                                                  34   0.13 
11915                                                                  34   0.13 
31474                                                                  34   0.18 
15337                                                                  34   0.18 
01805                                                                  33   0.32 
09883                                                                  32   0.41 
29912                                                                  32   0.56 
03044                                                                  32   0.79 
00499                                                                  32   0.81 
25400                                                                  31   0.94 
04955                                                                  30   1.9  
34511                                                                  30   2.0  
20271                                                                  30   2.3  
30176                                                                  30   2.5  
27681                                                                  30   3.1  
20036                                                                  29   4.5  
04524                                                                  28   6.9  
13509                                                                  28   7.0  
17298                                                                  28   9.0  
25522                                                                  28   9.7  
>16199
          Length = 694

 Score =  172 bits (435), Expect = 3e-43,   Method: Compositional matrix adjust.
 Identities = 94/182 (51%), Positives = 116/182 (63%), Gaps = 6/182 (3%)
 Frame = +1

Query: 329 YWAFSDIQTGRVLTKVTDETSGCSLTCAQFHP-----DGLIFGTGTM-DSQIKIWDLKER 382
           +WAFSDI+TGRVLTK   +    S  C+   P       L  G G + D  + +    ER
Sbjct: 1   HWAFSDIRTGRVLTKSVRQKWALS-ACSDMRPVPP*RSDLCDGDGGLCDQDLGLEGACER 177

Query: 383 TNVANFPGHSGPITSIAFSENGYYLATAADDSSVKLWDLRKLKNFKTLQLDNNFEVKSLI 442
                 PG  G         NGYYLAT+A+DS VKLWDLRKLKNFKTLQL + +EVK+L 
Sbjct: 178 ---GQLPGPPGTRHLHLLL*NGYYLATSAEDSVVKLWDLRKLKNFKTLQLGDKYEVKALC 348

Query: 443 FDQSGTYLALGGTDVQIYICKQWTEILHFTEHSGLTTGVAFGHHAKFIASTGMDRSLKFY 502
           FDQSGTYLA+ G+DV++Y+CKQW E+  F +H+   TGV FG +A FIAS  MDRSLKF+
Sbjct: 349 FDQSGTYLAVAGSDVRVYLCKQWNELAVFNDHTATATGVRFGTNANFIASASMDRSLKFF 528

Query: 503 SL 504
            L
Sbjct: 529 GL 534

 Score = 31.6 bits (70), Expect = 0.70,   Method: Compositional matrix adjust.
 Identities = 14/51 (27%), Positives = 25/51 (49%)
 Frame = +2

Query: 267 VTSVVFHPSQELVFSASPDATIRIWSVPNTSCVQVVRAHESAVTGLSLHAT 317
           +T   FHP   +  + + D+ I+IW +   + V   + H+  VT +S   T
Sbjct: 80  LTCAQFHPDGLIFATGTEDSVIKIWDLKERANVANFQGHQGPVTSISFSET 232
>30256
          Length = 961

 Score = 77.8 bits (190), Expect = 9e-15,   Method: Compositional matrix adjust.
 Identities = 58/201 (28%), Positives = 95/201 (47%), Gaps = 6/201 (2%)
 Frame = +3

Query: 236 KILTGGADKNVVVFDKSTEQILATLKGHTKKVTSVVFHPSQELVFSASPDATIRIWSVPN 295
           K+++G  D  + V+D  +   L  L GH   V  V +   +  V S + D T+R+W    
Sbjct: 198 KVVSGSRDATLRVWDIESGHCLNVLLGHMAAVRCVQYDGKR--VVSGAXDYTVRVWDPDT 371

Query: 296 TSCVQVVRAHESAVTGLSLHATGDYLLSSSDDQYWAFSDIQTGRVLTKVTDETSGCSLTC 355
            SC+  ++ H + V   SL   G Y++S S D      D++ G+++  +    S   LT 
Sbjct: 372 ASCLHTLQGHTNRV--YSLQFDGVYVVSGSLDTSIRVWDVRCGKLVHTLMGHQS---LTS 536

Query: 356 AQFHPDGLIFGTGTMDSQIKIWDLKERTNVANFPG---HSGPITSIAFSENGYYLATAAD 412
                D L+  +G  DS +K+WD+     +    G   H   +T + F  N  ++ T +D
Sbjct: 537 GLELKDNLLV-SGNADSTVKVWDVHTGKCLQTLLGPNKHRSAVTCLQF--NKKFVVTCSD 707

Query: 413 DSSVKLWDLRK---LKNFKTL 430
           D +VKLWDL     ++N  TL
Sbjct: 708 DGTVKLWDLNTGDFIRNLITL 770

 Score = 75.9 bits (185), Expect = 3e-14,   Method: Compositional matrix adjust.
 Identities = 54/196 (27%), Positives = 96/196 (48%)
 Frame = +3

Query: 235 NKILTGGADKNVVVFDKSTEQILATLKGHTKKVTSVVFHPSQELVFSASPDATIRIWSVP 294
           N +++G  D+++ V++  T     TL GH+  V  +    S + V S S DAT+R+W + 
Sbjct: 75  NTVISGSTDRSLKVWNADTGVCTHTLYGHSSTVRCLSL--SGKKVVSGSRDATLRVWDIE 248

Query: 295 NTSCVQVVRAHESAVTGLSLHATGDYLLSSSDDQYWAFSDIQTGRVLTKVTDETSGCSLT 354
           +  C+ V+  H +AV    +   G  ++S + D      D  T   L  +   T+   + 
Sbjct: 249 SGHCLNVLLGHMAAVR--CVQYDGKRVVSGAXDYTVRVWDPDTASCLHTLQGHTN--RVY 416

Query: 355 CAQFHPDGLIFGTGTMDSQIKIWDLKERTNVANFPGHSGPITSIAFSENGYYLATAADDS 414
             QF  DG+   +G++D+ I++WD++    V    GH    + +   +N   L +   DS
Sbjct: 417 SLQF--DGVYVVSGSLDTSIRVWDVRCGKLVHTLMGHQSLTSGLELKDN--LLVSGNADS 584

Query: 415 SVKLWDLRKLKNFKTL 430
           +VK+WD+   K  +TL
Sbjct: 585 TVKVWDVHTGKCLQTL 632
>13335
          Length = 863

 Score = 74.7 bits (182), Expect = 8e-14,   Method: Compositional matrix adjust.
 Identities = 69/242 (28%), Positives = 98/242 (40%), Gaps = 24/242 (9%)
 Frame = +1

Query: 246 VVVFDKSTEQILATLKGHTKKVTSVV-FHPSQELVFSASPDATIRIWSVPNTSCVQVVRA 304
           V+V+D  T  I    +  +K    V  F PS   + S S D TI +W V     V+    
Sbjct: 4   VIVWDVKTGSIKGEYQHASKSSIRVCKFSPSSSHLVSGSDDDTICMWEVATQKLVRSYVG 183

Query: 305 HESAVTGLSLHATGDYLLSSS---DDQYWAFSDIQTGRVLTKVTDETSGCSLTCAQFHPD 361
           HE +V  L+    G YL+S S   D   W  S      +  +V     G  +TC +F P 
Sbjct: 184 HEDSVMALAYSPNGHYLVSGSPNGDLYVWDASFGHCRHLTLRVDAHDLG--VTCCEFSPT 357

Query: 362 ------------GLIFGTGTMDSQIKIWDLKERTNVAN--------FPGHSGPITSIAFS 401
                        L+  TG  D+ IK+W    +               GHS  + + AFS
Sbjct: 358 FGTACAENSSTCNLLLATGGKDNLIKLWTFSAQVGSPEVTLQCRDILSGHSDLVMACAFS 537

Query: 402 ENGYYLATAADDSSVKLWDLRKLKNFKTLQLDNNFEVKSLIFDQSGTYLALGGTDVQIYI 461
            +   LA+ + D SV+LWD  K     +++  ++  V    F   GT LA G  D  I I
Sbjct: 538 PSSALLASGSFDKSVRLWDSVKGVALFSIEACHSRFVTCCAFSIDGTLLASGSMDRIIKI 717

Query: 462 CK 463
            K
Sbjct: 718 WK 723

 Score = 67.8 bits (164), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 57/228 (25%), Positives = 103/228 (45%), Gaps = 25/228 (10%)
 Frame = +1

Query: 219 ASIPGILALDLCPSDTNKILTGGADKNVVVFDKSTEQILATLKGHTKKVTSVVFHPSQEL 278
           AS   I      PS ++ +++G  D  + +++ +T++++ +  GH   V ++ + P+   
Sbjct: 55  ASKSSIRVCKFSPSSSH-LVSGSDDDTICMWEVATQKLVRSYVGHEDSVMALAYSPNGHY 231

Query: 279 VFSASPDATIRIWSVPNTSCVQV---VRAHESAVTGLSL-----------HATGDYLLSS 324
           + S SP+  + +W      C  +   V AH+  VT                +T + LL++
Sbjct: 232 LVSGSPNGDLYVWDASFGHCRHLTLRVDAHDLGVTCCEFSPTFGTACAENSSTCNLLLAT 411

Query: 325 SDD----QYWAFS-DIQTGRVLTKVTDETSGCS---LTCAQFHPDGLIFGTGTMDSQIKI 376
                  + W FS  + +  V  +  D  SG S   + CA F P   +  +G+ D  +++
Sbjct: 412 GGKDNLIKLWTFSAQVGSPEVTLQCRDILSGHSDLVMACA-FSPSSALLASGSFDKSVRL 588

Query: 377 WDLKERTNVANF---PGHSGPITSIAFSENGYYLATAADDSSVKLWDL 421
           WD      VA F     HS  +T  AFS +G  LA+ + D  +K+W L
Sbjct: 589 WD--SVKGVALFSIEACHSRFVTCCAFSIDGTLLASGSMDRIIKIWKL 726
>00561
          Length = 1003

 Score = 72.8 bits (177), Expect = 3e-13,   Method: Compositional matrix adjust.
 Identities = 62/250 (24%), Positives = 109/250 (43%), Gaps = 16/250 (6%)
 Frame = -3

Query: 231 PSDTNKILTGGADKNVVVF------DKSTEQILATLKGHTKKVTSVVFHPSQELVFSASP 284
           P D + I++   DK ++V+      D +       L GH+  ++ VV         S S 
Sbjct: 983 PKDPDTIISASRDKTLIVWKLTRDEDTNYGYPQKRLYGHSHFISDVVLSSDGNYALSGSW 804

Query: 285 DATIRIWSVPNTSCVQVVRAHESAVTGLSLHATGDYLLSSSDDQYWAFSDIQTGRVL--T 342
           D T+R+W +      +    H   V  ++  A    ++S S D+      I+    L   
Sbjct: 803 DQTLRLWDLAAGKTTRRFEGHTKDVLSVAFSADNRQIVSGSRDK-----TIKLWNTLAEC 639

Query: 343 KVTDETSGCS--LTCAQF---HPDGLIFGTGTMDSQIKIWDLKERTNVANFPGHSGPITS 397
           K T +  G +  ++C +F   H + +I   G  D  +K+W+L       N  GH+G + +
Sbjct: 638 KFTIQEDGHTDWVSCVRFSPNHSNPIIVSCG-WDRTVKVWNLANCKLKNNHHGHNGYLNT 462

Query: 398 IAFSENGYYLATAADDSSVKLWDLRKLKNFKTLQLDNNFEVKSLIFDQSGTYLALG-GTD 456
           +  S +G    +   DS   LWDL   KN  TL+  +N  + +L F  +  +L +  G  
Sbjct: 461 VTVSPDGSLCTSGGKDSKALLWDLNDGKNLYTLE--HNDIINALCFSPNRYWLCVAYGPS 288

Query: 457 VQIY--ICKQ 464
           ++I+   CK+
Sbjct: 287 IKIWDLACKK 258
>17598
          Length = 875

 Score = 72.0 bits (175), Expect = 5e-13,   Method: Compositional matrix adjust.
 Identities = 60/238 (25%), Positives = 109/238 (45%), Gaps = 14/238 (5%)
 Frame = +1

Query: 237 ILTGGADKNVVVFD----KSTEQI------LATLKGHTKKVTSVVFHPSQELVFSASPDA 286
           ++ GG DK ++V+D    K  ++         TL+GH+  V+ V        V S+S DA
Sbjct: 10  LIXGGRDKLLIVWDLVPRKDGDEDETWGGPRRTLQGHSHFVSDVSLSADSRYVLSSSWDA 189

Query: 287 TIRIWSVPNTSCVQVVRAHESAVTGLSLHATGDYLLSSSDDQYWAFSDIQTGRVLTKVTD 346
           T+R+W +   +  +   +H      ++       + S   D+     +   G     V  
Sbjct: 190 TLRLWDIKKGNTTRRFISHTRDALAVAFSPDNRQIASGGRDKALKIWNT-VGECKFTVDA 366

Query: 347 ETSGCSLTCAQFHPDGL--IFGTGTMDSQIKIWDLKERTNVANFPGHSGPITSIAFSENG 404
            +    +TC +FH D    +  + +MD  IK+WD +  T    F GH   I +I  +   
Sbjct: 367 NSHQDWVTCVKFHQDAKSPLVVSASMDKTIKVWDNQTMTLKHTFVGHKTQINAIDLALKT 546

Query: 405 YYLATAADDSSVKLWDLRKLKNFKTL-QLDNNFEVKSLIFDQSGTYLALGGTD-VQIY 460
           YYLA+ + D  V  W+   ++N   L ++D + EV ++ F  +  +L +G ++ +QI+
Sbjct: 547 YYLASGSKDGIVMTWN---IQNGTFLGKIDCDCEVNAVKFSPNKYWLFVGTSEGIQIW 711

 Score = 32.7 bits (73), Expect = 0.36,   Method: Compositional matrix adjust.
 Identities = 30/146 (20%), Positives = 54/146 (36%), Gaps = 10/146 (6%)
 Frame = +1

Query: 368 GTMDSQIKIWDLKERTN----------VANFPGHSGPITSIAFSENGYYLATAADDSSVK 417
           G  D  + +WDL  R +               GHS  ++ ++ S +  Y+ +++ D++++
Sbjct: 19  GGRDKLLIVWDLVPRKDGDEDETWGGPRRTLQGHSHFVSDVSLSADSRYVLSSSWDATLR 198

Query: 418 LWDLRKLKNFKTLQLDNNFEVKSLIFDQSGTYLALGGTDVQIYICKQWTEILHFTEHSGL 477
           LWD++K                             G T               F  H+  
Sbjct: 199 LWDIKK-----------------------------GNT------------TRRFISHTRD 255

Query: 478 TTGVAFGHHAKFIASTGMDRSLKFYS 503
              VAF    + IAS G D++LK ++
Sbjct: 256 ALAVAFSPDNRQIASGGRDKALKIWN 333
>02147
          Length = 1547

 Score = 71.6 bits (174), Expect = 7e-13,   Method: Compositional matrix adjust.
 Identities = 51/188 (27%), Positives = 90/188 (47%), Gaps = 1/188 (0%)
 Frame = +2

Query: 233 DTNKILTGGADKNVVVFD-KSTEQILATLKGHTKKVTSVVFHPSQELVFSASPDATIRIW 291
           D   +LTG  +K + VFD  +T+    +  GHT  +   +F    + + SAS D T+R+W
Sbjct: 329 DGTALLTGSNEKLLKVFDLVNTDAEPKSFAGHTSNIKGALFLSDGKRIISASDDKTVRLW 508

Query: 292 SVPNTSCVQVVRAHESAVTGLSLHATGDYLLSSSDDQYWAFSDIQTGRVLTKVTDETSGC 351
           S+     VQ +   ++  T L+L    + ++ +   Q  AF    T R + K   E    
Sbjct: 509 SLETCQEVQQL-TFDTPPTSLTLSPDKNTIIVTHS-QNIAFYQADTLREMKKFEAE---A 673

Query: 352 SLTCAQFHPDGLIFGTGTMDSQIKIWDLKERTNVANFPGHSGPITSIAFSENGYYLATAA 411
            ++ A  H     F  G  D ++  +D +    + +F GH GP+  + FS +G   A+ +
Sbjct: 674 PISSASLHQSERFFVAGGEDFKMYKFDYETGKEIESFKGHFGPVHCVRFSPDGELYASGS 853

Query: 412 DDSSVKLW 419
           +D +++LW
Sbjct: 854 EDGTLRLW 877

 Score = 44.3 bits (103), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 53/245 (21%), Positives = 87/245 (35%), Gaps = 41/245 (16%)
 Frame = +2

Query: 299 VQVVRAHESAVTGLSLHATGDYLLSSSDDQYWAFSDIQTGRVLTKVTDETSGCSLTCAQF 358
           +     H+ AV G +L+       + + D      D + G  L   + +     +    F
Sbjct: 152 IGTFEGHKGAVWGATLNREATRAATGAADFSAKIWDAEKGEELQTFSHK---HIVKSVDF 322

Query: 359 HPDGLIFGTGTMDSQIKIWDL-KERTNVANFPGHSGPITSIAFSENGYYLATAADDSSVK 417
             DG    TG+ +  +K++DL        +F GH+  I    F  +G  + +A+DD +V+
Sbjct: 323 SHDGTALLTGSNEKLLKVFDLVNTDAEPKSFAGHTSNIKGALFLSDGKRIISASDDKTVR 502

Query: 418 LWDLRKLKNFKTLQLD----------------------------------NNFEVKSLI- 442
           LW L   +  + L  D                                    FE ++ I 
Sbjct: 503 LWSLETCQEVQQLTFDTPPTSLTLSPDKNTIIVTHSQNIAFYQADTLREMKKFEAEAPIS 682

Query: 443 ---FDQSGTYLALGGTDVQIYICKQWT--EILHFTEHSGLTTGVAFGHHAKFIASTGMDR 497
                QS  +   GG D ++Y     T  EI  F  H G    V F    +  AS   D 
Sbjct: 683 SASLHQSERFFVAGGEDFKMYKFDYETGKEIESFKGHFGPVHCVRFSPDGELYASGSEDG 862

Query: 498 SLKFY 502
           +L+ +
Sbjct: 863 TLRLW 877

 Score = 43.1 bits (100), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 33/123 (26%), Positives = 53/123 (43%), Gaps = 3/123 (2%)
 Frame = +2

Query: 385 VANFPGHSGPITSIAFSENGYYLATAADDSSVKLWDLRKLKNFKTLQLDNNFEVKSLIFD 444
           +  F GH G +     +      AT A D S K+WD  K +  +T    +   VKS+ F 
Sbjct: 152 IGTFEGHKGAVWGATLNREATRAATGAADFSAKIWDAEKGEELQTFS--HKHIVKSVDFS 325

Query: 445 QSGTYLALGGTD--VQIY-ICKQWTEILHFTEHSGLTTGVAFGHHAKFIASTGMDRSLKF 501
             GT L  G  +  ++++ +     E   F  H+    G  F    K I S   D++++ 
Sbjct: 326 HDGTALLTGSNEKLLKVFDLVNTDAEPKSFAGHTSNIKGALFLSDGKRIISASDDKTVRL 505

Query: 502 YSL 504
           +SL
Sbjct: 506 WSL 514
>19949
          Length = 903

 Score = 70.9 bits (172), Expect = 1e-12,   Method: Compositional matrix adjust.
 Identities = 40/166 (24%), Positives = 77/166 (46%)
 Frame = +2

Query: 267 VTSVVFHPSQELVFSASPDATIRIWSVPNTSCVQVVRAHESAVTGLSLHATGDYLLSSSD 326
           V S+ FHP      S S D  +++W +    C+   + H   V  L     G ++ S+S+
Sbjct: 2   VKSLDFHPYGAYTASGSMDCNVKLWDIRRKGCIYTYKGHTGCVCCLRFSPDGRWIASASE 181

Query: 327 DQYWAFSDIQTGRVLTKVTDETSGCSLTCAQFHPDGLIFGTGTMDSQIKIWDLKERTNVA 386
           D      D+  G++LT +       ++   +FHP   +  +G+ D  +K WDL+    ++
Sbjct: 182 DGLVKLWDLTAGKLLTDLKLHRD--AVNTIEFHPHEFLLASGSADRTVKFWDLETFQLIS 355

Query: 387 NFPGHSGPITSIAFSENGYYLATAADDSSVKLWDLRKLKNFKTLQL 432
                +  I SI F  +G  L + + D ++K++    L+ + T+ +
Sbjct: 356 TTEPEANSIRSILFHPDGVCLYSGSKD-TLKVYHWEPLELYDTVSV 490

 Score = 70.5 bits (171), Expect = 1e-12,   Method: Compositional matrix adjust.
 Identities = 34/102 (33%), Positives = 57/102 (55%)
 Frame = +2

Query: 358 FHPDGLIFGTGTMDSQIKIWDLKERTNVANFPGHSGPITSIAFSENGYYLATAADDSSVK 417
           FHP G    +G+MD  +K+WD++ +  +  + GH+G +  + FS +G ++A+A++D  VK
Sbjct: 17  FHPYGAYTASGSMDCNVKLWDIRRKGCIYTYKGHTGCVCCLRFSPDGRWIASASEDGLVK 196

Query: 418 LWDLRKLKNFKTLQLDNNFEVKSLIFDQSGTYLALGGTDVQI 459
           LWDL   K    L+L  +  V ++ F      LA G  D  +
Sbjct: 197 LWDLTAGKLLTDLKLHRD-AVNTIEFHPHEFLLASGSADRTV 319

 Score = 67.4 bits (163), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 42/152 (27%), Positives = 74/152 (48%), Gaps = 1/152 (0%)
 Frame = +2

Query: 239 TGGADKNVVVFDKSTEQILATLKGHTKKVTSVVFHPSQELVFSASPDATIRIWSVPNTSC 298
           +G  D NV ++D   +  + T KGHT  V  + F P    + SAS D  +++W +     
Sbjct: 44  SGSMDCNVKLWDIRRKGCIYTYKGHTGCVCCLRFSPDGRWIASASEDGLVKLWDLTAGKL 223

Query: 299 VQVVRAHESAVTGLSLHATGDYLLSSSDDQYWAFSDIQTGRVLTKVTDETSGCSLTCAQF 358
           +  ++ H  AV  +  H     L S S D+   F D++T ++++  T E    S+    F
Sbjct: 224 LTDLKLHRDAVNTIEFHPHEFLLASGSADRTVKFWDLETFQLIS--TTEPEANSIRSILF 397

Query: 359 HPDGLIFGTGTMDS-QIKIWDLKERTNVANFP 389
           HPDG+   +G+ D+ ++  W+  E  +  + P
Sbjct: 398 HPDGVCLYSGSKDTLKVYHWEPLELYDTVSVP 493

 Score = 65.9 bits (159), Expect = 3e-11,   Method: Compositional matrix adjust.
 Identities = 43/153 (28%), Positives = 70/153 (45%), Gaps = 1/153 (0%)
 Frame = +2

Query: 309 VTGLSLHATGDYLLSSSDDQYWAFSDIQTGRVLTKVTDETSGCSLTCAQFHPDGLIFGTG 368
           V  L  H  G Y  S S D      DI+    +      T GC + C +F PDG    + 
Sbjct: 2   VKSLDFHPYGAYTASGSMDCNVKLWDIRRKGCIYTYKGHT-GC-VCCLRFSPDGRWIASA 175

Query: 369 TMDSQIKIWDLKERTNVANFPGHSGPITSIAFSENGYYLATAADDSSVKLWDLRKLKNFK 428
           + D  +K+WDL     + +   H   + +I F  + + LA+ + D +VK WDL   +   
Sbjct: 176 SEDGLVKLWDLTAGKLLTDLKLHRDAVNTIEFHPHEFLLASGSADRTVKFWDLETFQLIS 355

Query: 429 TLQLDNNFEVKSLIFDQSGTYLALGGTD-VQIY 460
           T + + N  ++S++F   G  L  G  D +++Y
Sbjct: 356 TTEPEAN-SIRSILFHPDGVCLYSGSKDTLKVY 451

 Score = 46.6 bits (109), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 27/104 (25%), Positives = 46/104 (44%)
 Frame = +2

Query: 224 ILALDLCPSDTNKILTGGADKNVVVFDKSTEQILATLKGHTKKVTSVVFHPSQELVFSAS 283
           +  L   P D   I +   D  V ++D +  ++L  LK H   V ++ FHP + L+ S S
Sbjct: 128 VCCLRFSP-DGRWIASASEDGLVKLWDLTAGKLLTDLKLHRDAVNTIEFHPHEFLLASGS 304

Query: 284 PDATIRIWSVPNTSCVQVVRAHESAVTGLSLHATGDYLLSSSDD 327
            D T++ W +     +       +++  +  H  G  L S S D
Sbjct: 305 ADRTVKFWDLETFQLISTTEPEANSIRSILFHPDGVCLYSGSKD 436

 Score = 33.1 bits (74), Expect = 0.30,   Method: Compositional matrix adjust.
 Identities = 21/69 (30%), Positives = 33/69 (47%), Gaps = 2/69 (2%)
 Frame = +2

Query: 438 VKSLIFDQSGTYLALGGTD--VQIYICKQWTEILHFTEHSGLTTGVAFGHHAKFIASTGM 495
           VKSL F   G Y A G  D  V+++  ++   I  +  H+G    + F    ++IAS   
Sbjct: 2   VKSLDFHPYGAYTASGSMDCNVKLWDIRRKGCIYTYKGHTGCVCCLRFSPDGRWIASASE 181

Query: 496 DRSLKFYSL 504
           D  +K + L
Sbjct: 182 DGLVKLWDL 208
>03395
          Length = 2795

 Score = 69.7 bits (169), Expect = 3e-12,   Method: Compositional matrix adjust.
 Identities = 53/209 (25%), Positives = 93/209 (44%), Gaps = 12/209 (5%)
 Frame = +2

Query: 223 GILALDLCPSDTNKILTGGADKNVVVFD--------KSTEQILATLKGHTKKVTSVVFHP 274
           G+ A+ +    T K+++GG +  V V+D        K+   ++A +K H  KVT++  H 
Sbjct: 2   GVTAIAVTSCGT-KLVSGGGEGQVRVWDIVKDMLTGKTRGDLVANMKEHKGKVTAIQIHT 178

Query: 275 SQELVFSASPDATIRIWSVPNTSCVQVVRAHE----SAVTGLSLHATGDYLLSSSDDQYW 330
           +     SAS D +  IW +   +  Q+V A+         G  LH     +L+S  D   
Sbjct: 179 NDRCCVSASTDGSTIIWDLITNTRSQIVLANTLFKCVCFGGKDLH-----ILTSGTDHKI 343

Query: 331 AFSDIQTGRVLTKVTDETSGCSLTCAQFHPDGLIFGTGTMDSQIKIWDLKERTNVANFPG 390
            + ++  G +L ++    +G ++       DG    TG  DS +K+W   E        G
Sbjct: 344 GYWEVGDGGLLRELEGSQTG-AINTIDIDRDGQTILTGGEDSLLKLWRYNEGEVTHTGIG 520

Query: 391 HSGPITSIAFSENGYYLATAADDSSVKLW 419
           HS  IT      N +Y+ +  +D ++ +W
Sbjct: 521 HSNQITKARICPNRHYIVSGGEDGALHIW 607

 Score = 41.2 bits (95), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 28/101 (27%), Positives = 48/101 (47%), Gaps = 8/101 (7%)
 Frame = +2

Query: 367 TGTMDSQIKIWDL-------KERTN-VANFPGHSGPITSIAFSENGYYLATAADDSSVKL 418
           +G  + Q+++WD+       K R + VAN   H G +T+I    N     +A+ D S  +
Sbjct: 47  SGGGEGQVRVWDIVKDMLTGKTRGDLVANMKEHKGKVTAIQIHTNDRCCVSASTDGSTII 226

Query: 419 WDLRKLKNFKTLQLDNNFEVKSLIFDQSGTYLALGGTDVQI 459
           WDL  + N ++  +  N   K + F     ++   GTD +I
Sbjct: 227 WDL--ITNTRSQIVLANTLFKCVCFGGKDLHILTSGTDHKI 343

 Score = 39.7 bits (91), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 19/73 (26%), Positives = 34/73 (46%)
 Frame = +2

Query: 233 DTNKILTGGADKNVVVFDKSTEQILATLKGHTKKVTSVVFHPSQELVFSASPDATIRIWS 292
           D   ILTGG D  + ++  +  ++  T  GH+ ++T     P++  + S   D  + IW 
Sbjct: 431 DGQTILTGGEDSLLKLWRYNEGEVTHTGIGHSNQITKARICPNRHYIVSGGEDGALHIWK 610

Query: 293 VPNTSCVQVVRAH 305
            P+   V  +  H
Sbjct: 611 FPDGC*VDCLPRH 649
>02090
          Length = 1841

 Score = 66.6 bits (161), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 43/151 (28%), Positives = 71/151 (47%), Gaps = 8/151 (5%)
 Frame = -3

Query: 360  PDGLIFGTGTMDSQIKIWDLKERTNVANFPGHSGPITSIAFSENGYYLATAADDSSVKLW 419
            PDG +  +   D  I +WDL  +T V  F GH+   + I  S +G  L T   D++V+ W
Sbjct: 1596 PDGKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISPDGTKLWTGGLDNTVRSW 1417

Query: 420  DLRKLKNFKTLQLDNNFEVKSLIFDQSGTYLALGGTDVQIYICKQWTEILHFTE------ 473
            DLR+ +  +  Q D + ++ SL +  +G +LA+G     +       E+LH ++      
Sbjct: 1416 DLREGRQLQ--QHDFSSQIFSLGYCPTGEWLAVGMESSNV-------EVLHHSKPDKYQL 1264

Query: 474  --HSGLTTGVAFGHHAKFIASTGMDRSLKFY 502
              H      + F +  K+  STG D  L  +
Sbjct: 1263 HLHESCVLSLKFAYCGKWFVSTGKDNLLNAW 1171

 Score = 38.1 bits (87), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 24/104 (23%), Positives = 46/104 (44%)
 Frame = -3

Query: 218  SASIPGILALDLCPSDTNKILTGGADKNVVVFDKSTEQILATLKGHTKKVTSVVFHPSQE 277
            ++S P   AL + P D     +  +D N+ V+D   + ++   +GHT   + +   P   
Sbjct: 1635 TSSAPACYALAISP-DGKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISPDGT 1459

Query: 278  LVFSASPDATIRIWSVPNTSCVQVVRAHESAVTGLSLHATGDYL 321
             +++   D T+R W +     +Q      S +  L    TG++L
Sbjct: 1458 KLWTGGLDNTVRSWDLREGRQLQ-QHDFSSQIFSLGYCPTGEWL 1330
>01327
          Length = 2215

 Score = 65.5 bits (158), Expect = 4e-11,   Method: Compositional matrix adjust.
 Identities = 63/248 (25%), Positives = 101/248 (40%), Gaps = 48/248 (19%)
 Frame = +3

Query: 238 LTGGADKNVVVFDKSTEQILATLKGHTKKVTSVVFHPSQELVFSASPDATIRIWSVPNTS 297
           L+G  DK+VV++D    ++     GH +++T V +  S   +FSAS D TI++W   N+ 
Sbjct: 87  LSGSKDKSVVLYDYQNGRLEDRWTGHDREITKVCYGASCNGMFSASRDKTIKMWQRGNSH 266

Query: 298 CVQVVRAHESAVTGLSLHATGDYLLSSSDDQYWAFSDIQTGRVLTK-------VTD---- 346
            ++    H+  VT + L+     L S S D      D++TG  L +       VTD    
Sbjct: 267 SIRDFIGHDMVVTAIHLNTDNTLLCSGSRDNTVRIWDVETGACLRQNNIPQNLVTDVKWL 446

Query: 347 --------------------ETSGC--SLTCAQF-------HPDGLIF-----GTGTMDS 372
                                T G   S T  Q+         DG        G G    
Sbjct: 447 PGSHLIIQAGEDKEVRIYDSRTLGIVRSFTKKQYIQMSCDVTADGQFCLTCSNGFGGNGC 626

Query: 373 QIKIWDLKERTNVANFPGHSGPITSIAF---SENGYYLATAADDSSVKLWDLRKLKNFKT 429
           +  +W L + +    F GH   I +  F   +++   +ATA+ D SV++W++      K 
Sbjct: 627 EATLWQLSDGSIQNEFKGHREAIEACLFLPSNQDMTLIATASRDCSVRVWNMFT----KE 794

Query: 430 LQLDNNFE 437
              + NFE
Sbjct: 795 CVCEQNFE 818
>17266
          Length = 480

 Score = 64.7 bits (156), Expect = 8e-11,   Method: Composition-based stats.
 Identities = 38/143 (26%), Positives = 63/143 (44%), Gaps = 2/143 (1%)
 Frame = -1

Query: 274 PSQELVFSASPDATIRIWSVPNTSCVQVVRAHESAVTGLSLHATGDYLLSSSDDQYWAFS 333
           P      S + DA+ ++W V +  C Q    HES +  ++    G    + SDD      
Sbjct: 429 PDMRTFVSGACDASAKLWDVRDGMCKQTFSGHESDINAITYFPNGHAFATGSDDATCRLF 250

Query: 334 DIQTGRVLTKVTDETSGCSLTCAQFHPDGLIFGTGTMDSQIKIWDL--KERTNVANFPGH 391
           DI+  + +   + +   C +T   F   G +   G  D    IWD+  +ERT V    GH
Sbjct: 249 DIRADQEIGMYSHDNIICGITSVAFSKSGRLLLGGYDDFNCNIWDVLKQERTGV--LAGH 76

Query: 392 SGPITSIAFSENGYYLATAADDS 414
              ++ +  +E+G  +AT + DS
Sbjct: 75  DNRVSCLGVTEDGSAVATGSWDS 7

 Score = 62.4 bits (150), Expect = 4e-10,   Method: Composition-based stats.
 Identities = 39/122 (31%), Positives = 63/122 (51%), Gaps = 1/122 (0%)
 Frame = -1

Query: 360 PDGLIFGTGTMDSQIKIWDLKERTNVANFPGHSGPITSIAFSENGYYLATAADDSSVKLW 419
           PD   F +G  D+  K+WD+++      F GH   I +I +  NG+  AT +DD++ +L+
Sbjct: 429 PDMRTFVSGACDASAKLWDVRDGMCKQTFSGHESDINAITYFPNGHAFATGSDDATCRLF 250

Query: 420 DLRKLKNFKTLQLDNNF-EVKSLIFDQSGTYLALGGTDVQIYICKQWTEILHFTEHSGLT 478
           D+R  +       DN    + S+ F +SG  L LGG D   + C  W ++L   E +G+ 
Sbjct: 249 DIRADQEIGMYSHDNIICGITSVAFSKSGRLL-LGGYD--DFNCNIW-DVLK-QERTGVL 85

Query: 479 TG 480
            G
Sbjct: 84  AG 79

 Score = 32.3 bits (72), Expect = 0.51,   Method: Composition-based stats.
 Identities = 24/94 (25%), Positives = 38/94 (40%), Gaps = 3/94 (3%)
 Frame = -1

Query: 239 TGGADKNVVVFDKSTEQILATLKGHTK---KVTSVVFHPSQELVFSASPDATIRIWSVPN 295
           TG  D    +FD   +Q +  +  H      +TSV F  S  L+     D    IW V  
Sbjct: 282 TGSDDATCRLFDIRADQEIG-MYSHDNIICGITSVAFSKSGRLLLGGYDDFNCNIWDVLK 106

Query: 296 TSCVQVVRAHESAVTGLSLHATGDYLLSSSDDQY 329
                V+  H++ V+ L +   G  + + S D +
Sbjct: 105 QERTGVLAGHDNRVSCLGVTEDGSAVATGSWDSF 4
>12806
          Length = 961

 Score = 62.8 bits (151), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 49/197 (24%), Positives = 80/197 (40%), Gaps = 12/197 (6%)
 Frame = +3

Query: 237 ILTGGADKNVVVFD------KSTEQILA----TLKGHTKKVTSVVFHPSQELVFSASPDA 286
           +++GG D N++V+D         +Q       TL GH+  ++ +          S+S DA
Sbjct: 54  LISGGRDNNIIVWDL*PKKDGDEDQTWGVPRKTLTGHSHFISDLALSADSRFALSSSWDA 233

Query: 287 TIRIWSVPNTSCVQVVRAHESAVTGLSLHATGDYLLSSSDDQYWAFSDIQTGRVLTKVTD 346
           T+R+W +   S       H   V  ++       + S   D+     +I  G     V  
Sbjct: 234 TLRLWDIKKGSTTSRFINHTRDVLTVAFSPDNRQIASGGRDKNLKIWNIM-GECKYTVDA 410

Query: 347 ETSGCSLTCAQFHPD--GLIFGTGTMDSQIKIWDLKERTNVANFPGHSGPITSIAFSENG 404
                 +TC +FH D    I  + + D  IK+WD    T    F GH   IT++  S N 
Sbjct: 411 NAHTDWVTCVRFHQDTKNPIVVSASNDKTIKVWDNHTMTLKNTFVGHKAQITALDMSTN- 587

Query: 405 YYLATAADDSSVKLWDL 421
            YL + + D     W++
Sbjct: 588 -YLVSGSKDGIAMTWNV 635

 Score = 39.7 bits (91), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 33/151 (21%), Positives = 67/151 (44%), Gaps = 15/151 (9%)
 Frame = +3

Query: 367 TGTMDSQIKIWDLKERTN----------VANFPGHSGPITSIAFSENGYYLATAADDSSV 416
           +G  D+ I +WDL  + +               GHS  I+ +A S +  +  +++ D+++
Sbjct: 60  SGGRDNNIIVWDL*PKKDGDEDQTWGVPRKTLTGHSHFISDLALSADSRFALSSSWDATL 239

Query: 417 KLWDLRKLKNFKTLQLDNNFEVKSLIFDQSGTYLALGGTDVQIYICKQWTEILHFTE--- 473
           +LWD++K        +++  +V ++ F      +A GG D  + I     E  +  +   
Sbjct: 240 RLWDIKKGSTTSRF-INHTRDVLTVAFSPDNRQIASGGRDKNLKIWNIMGECKYTVDANA 416

Query: 474 HSGLTTGVAFGHHAK--FIASTGMDRSLKFY 502
           H+   T V F    K   + S   D+++K +
Sbjct: 417 HTDWVTCVRFHQDTKNPIVVSASNDKTIKVW 509
>17602
          Length = 481

 Score = 59.7 bits (143), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 36/136 (26%), Positives = 67/136 (49%), Gaps = 3/136 (2%)
 Frame = +3

Query: 289 RIWSVPNTSCVQVVRAHESAVTGLSLHATGDYLLSSSDDQYWAFSDIQTGRVLTKVTDET 348
           RIW V    C++ + AH   VT +  +  G  ++SSS D      D  +G+ L  + D+ 
Sbjct: 3   RIWDVKTGKCLKTLPAHSDPVTAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLXTLIDDD 182

Query: 349 SGCSLTCAQFHPDGLIFGTGTMDSQIKIWDLKERTNVANFPGHSGPITSI--AFS-ENGY 405
           +   ++  +F P+G      T+D+ +K+WD  +   +  + GH      I   FS   G 
Sbjct: 183 NP-PVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYVGHRNEKYCIFANFSVTGGK 359

Query: 406 YLATAADDSSVKLWDL 421
           ++ + ++D+ V +W+L
Sbjct: 360 WIVSGSEDNMVYIWNL 407

 Score = 48.1 bits (113), Expect = 7e-06,   Method: Compositional matrix adjust.
 Identities = 22/76 (28%), Positives = 41/76 (53%)
 Frame = +3

Query: 375 KIWDLKERTNVANFPGHSGPITSIAFSENGYYLATAADDSSVKLWDLRKLKNFKTLQLDN 434
           +IWD+K    +   P HS P+T++ F+ +G  + +++ D   ++WD    +   TL  D+
Sbjct: 3   RIWDVKTGKCLKTLPAHSDPVTAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLXTLIDDD 182

Query: 435 NFEVKSLIFDQSGTYL 450
           N  V  + F  +G Y+
Sbjct: 183 NPPVSFVKFSPNGKYI 230
>03387
          Length = 1891

 Score = 57.8 bits (138), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 48/179 (26%), Positives = 82/179 (45%), Gaps = 14/179 (7%)
 Frame = +1

Query: 260 LKGHTKKVTSVVFHPS-QELVFSASPDATIRIWSVPNT-------SCVQVVRAHESAVTG 311
           LKGH K+   + ++P+    + SAS D TI +W + +T           +   H S V  
Sbjct: 349 LKGHQKEGYGLSWNPNLNGHLLSASDDHTICLWDINSTQRESRVVDAHTIFTGHTSVVED 528

Query: 312 LSLHATGDYLLSS-SDDQYWAFSDIQTGRVL--TKVTDETSGCSLTCAQFHP-DGLIFGT 367
           ++ H   + L  S +DDQ     D ++      + V D  +   + C  F+P    I  T
Sbjct: 529 VAWHLLHESLFGSVADDQKLMIWDTRSNTTSKPSHVVDAHTA-EVNCLSFNPYSEFILAT 705

Query: 368 GTMDSQIKIWDLKE-RTNVANFPGHSGPITSIAFS-ENGYYLATAADDSSVKLWDLRKL 424
           G+ D  + +WDL+  +  + +F  H   I  + +S  N   LA++  D  + +WDL K+
Sbjct: 706 GSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLHVWDLSKI 882

 Score = 53.5 bits (127), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 54/189 (28%), Positives = 87/189 (46%), Gaps = 21/189 (11%)
 Frame = +1

Query: 294 PNTSCVQVVR--AHESAVTGLSLHAT-GDYLLSSSDDQYWAFSDIQTGRVLTKVTD---- 346
           P+  C+  +R   H+    GLS +     +LLS+SDD      DI + +  ++V D    
Sbjct: 319 PSGECIPELRLKGHQKEGYGLSWNPNLNGHLLSASDDHTICLWDINSTQRESRVVDAHTI 498

Query: 347 ---ETSGCSLTCAQFHPDGLIFGTGTMDSQIKIWDLKERTNVANFP-----GHSGPITSI 398
               TS           + L FG+   D ++ IWD   R+N  + P      H+  +  +
Sbjct: 499 FTGHTSVVEDVAWHLLHESL-FGSVADDQKLMIWDT--RSNTTSKPSHVVDAHTAEVNCL 669

Query: 399 AFSE-NGYYLATAADDSSVKLWDLRKLKNFKTLQLDNNFEVKSLIFD-----QSGTYLAL 452
           +F+  + + LAT + D +V LWDLR LK    L+L +    K  IF       + T LA 
Sbjct: 670 SFNPYSEFILATGSADKTVALWDLRNLK----LKLHSFESHKDEIFQVQWSPHNETILAS 837

Query: 453 GGTDVQIYI 461
            GTD ++++
Sbjct: 838 SGTDRRLHV 864
>03156
          Length = 1014

 Score = 56.6 bits (135), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 51/218 (23%), Positives = 92/218 (42%), Gaps = 15/218 (6%)
 Frame = +1

Query: 235 NKILTGGADKNVVVFDKSTEQILATLKGHTKKVTSVVFHPSQELVFSASPDATIRIWSVP 294
           N + +   DK + ++ +     +    GH   VT++  +    L+ S S D T+RIW V 
Sbjct: 94  NGMFSASRDKTIKMWQRGNSHSIRDFIGHDMVVTAIHLNTDNTLLCSGSRDNTVRIWDVE 273

Query: 295 NTSCVQVVRAHESAVTGLSLHATGDYLLSSSDDQYWAFSDIQT---GRVLTK-------- 343
             +C++     ++ VT +        ++ + +D+     D +T    R  TK        
Sbjct: 274 TGACLRQNNIPQNLVTDVKWLPGSHLIIQAGEDKEVRIYDSRTLGIVRSFTKKQYIQMSC 453

Query: 344 -VTDETSGCSLTCAQFHPDGLIFGTGTMDSQIKIWDLKERTNVANFPGHSGPITSIAF-- 400
            VT +   C LTC+         G G    +  +W L + +    F GH   I +  F  
Sbjct: 454 DVTADGQFC-LTCSN--------GFGGNGCEATLWQLSDGSIQNEFKGHREAIEACLFLP 606

Query: 401 -SENGYYLATAADDSSVKLWDLRKLKNFKTLQLDNNFE 437
            +++   +ATA+ D SV++W++      K    + NFE
Sbjct: 607 SNQDMTLIATASRDCSVRVWNMFT----KECVCEQNFE 708
>14500
          Length = 1238

 Score = 48.1 bits (113), Expect(2) = 3e-08,   Method: Compositional matrix adjust.
 Identities = 27/93 (29%), Positives = 49/93 (52%)
 Frame = +3

Query: 327 DQYWAFSDIQTGRVLTKVTDETSGCSLTCAQFHPDGLIFGTGTMDSQIKIWDLKERTNVA 386
           D++  F +  TG  L+ V  ++  C+L  ++ H + LI   G   +Q+ IW     + VA
Sbjct: 273 DRHIHFWNCNTGTNLSSVDTKSQVCALLWSKEHRE-LISSHGFAQNQLIIWKYPAMSRVA 449

Query: 387 NFPGHSGPITSIAFSENGYYLATAADDSSVKLW 419
              GH+  +  +A S +G  + +AA D +++LW
Sbjct: 450 ELTGHTARVLHMAMSPDGETVVSAAADETLRLW 548

 Score = 27.7 bits (60), Expect(2) = 3e-08,   Method: Compositional matrix adjust.
 Identities = 14/73 (19%), Positives = 35/73 (47%), Gaps = 5/73 (6%)
 Frame = +2

Query: 247 VVFDKSTEQILATLKGHTKKVTSVVFHPSQELVFSASPDATIRIWSVP-----NTSCVQV 301
           + + +  +  + TL GH+++V  + + P  + + S + D  + +W        +T  +  
Sbjct: 8   LYYGRVADHHVGTLSGHSQEVCGLRWSPDGKYLASGANDNLLCVWPAQVTGGNSTQPLHT 187

Query: 302 VRAHESAVTGLSL 314
              H++AV  L++
Sbjct: 188 FSQHQAAVKALAV 226

 Score = 37.4 bits (85), Expect = 0.013,   Method: Compositional matrix adjust.
 Identities = 17/52 (32%), Positives = 27/52 (51%)
 Frame = +3

Query: 240 GGADKNVVVFDKSTEQILATLKGHTKKVTSVVFHPSQELVFSASPDATIRIW 291
           G A   ++++       +A L GHT +V  +   P  E V SA+ D T+R+W
Sbjct: 393 GFAQNQLIIWKYPAMSRVAELTGHTARVLHMAMSPDGETVVSAAADETLRLW 548

 Score = 29.6 bits (65), Expect = 2.7,   Method: Compositional matrix adjust.
 Identities = 12/36 (33%), Positives = 22/36 (61%)
 Frame = +2

Query: 384 NVANFPGHSGPITSIAFSENGYYLATAADDSSVKLW 419
           +V    GHS  +  + +S +G YLA+ A+D+ + +W
Sbjct: 35  HVGTLSGHSQEVCGLRWSPDGKYLASGANDNLLCVW 142
>15118
          Length = 1074

 Score = 54.3 bits (129), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 37/121 (30%), Positives = 56/121 (46%), Gaps = 3/121 (2%)
 Frame = +3

Query: 304 AHESAVTGLSLHATGDYLLSSSDD---QYWAFSDIQTGRVLTKVTDETSGCSLTCAQFHP 360
           AH S V G++  A    L+++  D   ++W F      RVL K    + G S      H 
Sbjct: 186 AHVSGVRGVAFDAFNCLLITAGGDCDIKFWRFGSRDRARVLLKELKMSEGISRI--LLHR 359

Query: 361 DGLIFGTGTMDSQIKIWDLKERTNVANFPGHSGPITSIAFSENGYYLATAADDSSVKLWD 420
           D  +      D  + + D+     V  F GHS  IT ++FS +G +L TA+ D +V+ W 
Sbjct: 360 DSNMLAVVLEDFTVSVIDVDTLRVVRVFSGHSNSITDLSFSGDGRWLITASMDCTVRTWS 539

Query: 421 L 421
           L
Sbjct: 540 L 542

 Score = 45.8 bits (107), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 28/96 (29%), Positives = 48/96 (50%)
 Frame = +3

Query: 229 LCPSDTNKILTGGADKNVVVFDKSTEQILATLKGHTKKVTSVVFHPSQELVFSASPDATI 288
           L   D+N +     D  V V D  T +++    GH+  +T + F      + +AS D T+
Sbjct: 348 LLHRDSNMLAVVLEDFTVSVIDVDTLRVVRVFSGHSNSITDLSFSGDGRWLITASMDCTV 527

Query: 289 RIWSVPNTSCVQVVRAHESAVTGLSLHATGDYLLSS 324
           R WS+ +   +    A E+AVT L++  + D+L +S
Sbjct: 528 RTWSLVHGRLIDCF-AVEAAVTSLTMSPSQDFLATS 632

 Score = 31.6 bits (70), Expect = 0.81,   Method: Compositional matrix adjust.
 Identities = 29/144 (20%), Positives = 59/144 (40%), Gaps = 7/144 (4%)
 Frame = +3

Query: 368 GTMDSQIKIWDL---KERTNVANFPGHSGPITSIAFSENGYYLATAADDSSVKLWDLRKL 424
           G     + I++L   K R +  +   H   +  +AF      L TA  D  +K W     
Sbjct: 111 GYSSGHLDIYNLQSGKHRGSFGDTVAHVSGVRGVAFDAFNCLLITAGGDCDIKFWRFGSR 290

Query: 425 KNFKTL--QLDNNFEVKSLIFDQSGTYLALGGTDVQIYICKQWT--EILHFTEHSGLTTG 480
              + L  +L  +  +  ++  +    LA+   D  + +    T   +  F+ HS   T 
Sbjct: 291 DRARVLLKELKMSEGISRILLHRDSNMLAVVLEDFTVSVIDVDTLRVVRVFSGHSNSITD 470

Query: 481 VAFGHHAKFIASTGMDRSLKFYSL 504
           ++F    +++ +  MD +++ +SL
Sbjct: 471 LSFSGDGRWLITASMDCTVRTWSL 542
>19498
          Length = 903

 Score = 53.9 bits (128), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 44/154 (28%), Positives = 67/154 (43%), Gaps = 9/154 (5%)
 Frame = -1

Query: 257 LATLKGHTKKVTSVVFHPSQELVFSASPDATIRIWSVPNTS-CVQVVRAHESAVTGLSLH 315
           +ATL+GH   V  + + P    + S S D TI +W+    S  V V+R H   V G++  
Sbjct: 630 VATLRGHAGDVLDLAWSPQDLWLASCSVDNTIVVWNALKFSEQVAVIRGHAGMVKGVTWD 451

Query: 316 ATGDYLLSSSDD---QYWAFSDIQTGRVLTKVTDETSGCS-LTCAQFHPDG-LIFGTGTM 370
             G YL S SDD   + W  SD +    +     E  G + +    + PDG  +     M
Sbjct: 450 PVGRYLASQSDDKTLRVWRTSDWKEETCVKSCFKECGGTTHVLRLNWSPDGNHVVSAHAM 271

Query: 371 DSQIKIWDLKERTNVA---NFPGHSGPITSIAFS 401
           ++      + ER       +F GH   IT + F+
Sbjct: 270 NNAXPTAQIIERNGWGTSLDFVGHRKAITVVRFN 169

 Score = 42.7 bits (99), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 41/179 (22%), Positives = 69/179 (38%), Gaps = 9/179 (5%)
 Frame = -1

Query: 250 DKSTEQILATLKGHTKKVTSVVFHPSQELVFSASPDATIRIWSVPNT--------SCVQV 301
           D    ++L  +  H   V  V +  + + + S   D  I IW +           S V +
Sbjct: 828 DDDVPRVLCQMDSHLGCVNCVRWSENGKFLASGGDDKLIMIWQISRGFGSGKSFGSNVTI 649

Query: 302 VRAHESAVTGLSLHATGDYLLSSSDDQYWAFSDIQTGRVLTKVTDETSGCSLTCAQFHPD 361
           +  H  +V  L  HA GD L     D  W+                            P 
Sbjct: 648 LE-HWRSVATLRGHA-GDVL-----DLAWS----------------------------PQ 574

Query: 362 GLIFGTGTMDSQIKIWD-LKERTNVANFPGHSGPITSIAFSENGYYLATAADDSSVKLW 419
            L   + ++D+ I +W+ LK    VA   GH+G +  + +   G YLA+ +DD ++++W
Sbjct: 573 DLWLASCSVDNTIVVWNALKFSEQVAVIRGHAGMVKGVTWDPVGRYLASQSDDKTLRVW 397

 Score = 42.0 bits (97), Expect = 6e-04,   Method: Compositional matrix adjust.
 Identities = 38/173 (21%), Positives = 75/173 (43%), Gaps = 36/173 (20%)
 Frame = -1

Query: 366 GTGTMDS-QIKIWDL------KERTN------VANFPGHSGPITSIAFSENGYYLATAAD 412
           G G  DS ++ IW++      KE  +      +     H G +  + +SENG +LA+  D
Sbjct: 903 GQGEGDSGKVVIWNMAPIRDEKEEADDDVPRVLCQMDSHLGCVNCVRWSENGKFLASGGD 724

Query: 413 DSSVKLWDLRK--------------LKNFKTLQL--DNNFEVKSLIFDQSGTYLALGGTD 456
           D  + +W + +              L++++++     +  +V  L +     +LA    D
Sbjct: 723 DKLIMIWQISRGFGSGKSFGSNVTILEHWRSVATLRGHAGDVLDLAWSPQDLWLASCSVD 544

Query: 457 VQIYICKQWTEILHFTE-------HSGLTTGVAFGHHAKFIASTGMDRSLKFY 502
             I +   W   L F+E       H+G+  GV +    +++AS   D++L+ +
Sbjct: 543 NTIVV---WNA-LKFSEQVAVIRGHAGMVKGVTWDPVGRYLASQSDDKTLRVW 397

 Score = 37.4 bits (85), Expect = 0.014,   Method: Compositional matrix adjust.
 Identities = 28/90 (31%), Positives = 45/90 (50%), Gaps = 2/90 (2%)
 Frame = -1

Query: 204 LSKYRQVASHVGLHSASIPGILALDLCPSDTNKILTGGADKNVVVFD--KSTEQILATLK 261
           L  +R VA+  G H+  +   L L   P D   + +   D  +VV++  K +EQ+ A ++
Sbjct: 648 LEHWRSVATLRG-HAGDV---LDLAWSPQDL-WLASCSVDNTIVVWNALKFSEQV-AVIR 487

Query: 262 GHTKKVTSVVFHPSQELVFSASPDATIRIW 291
           GH   V  V + P    + S S D T+R+W
Sbjct: 486 GHAGMVKGVTWDPVGRYLASQSDDKTLRVW 397
>12574
          Length = 521

 Score = 52.4 bits (124), Expect = 5e-07,   Method: Compositional matrix adjust.
 Identities = 29/120 (24%), Positives = 61/120 (50%)
 Frame = +3

Query: 251 KSTEQILATLKGHTKKVTSVVFHPSQELVFSASPDATIRIWSVPNTSCVQVVRAHESAVT 310
           K T  +  TL GHTK +++V F P+ + + S+S D  I+IW   +    + +  H+  ++
Sbjct: 147 KPTYTLKFTLAGHTKALSAVKFSPNGDWLASSSADKLIKIWGAYDGKFEKTIAGHKLGLS 326

Query: 311 GLSLHATGDYLLSSSDDQYWAFSDIQTGRVLTKVTDETSGCSLTCAQFHPDGLIFGTGTM 370
            ++  +    L S+SDD+     +  TG+ +  +   ++   + C  F+P   +  +G++
Sbjct: 327 DVAWSSDSKLLCSASDDKTLKIWEFSTGKCMKTLKGHSN--YVFCCNFNPQSNLIVSGSL 500

 Score = 49.3 bits (116), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 24/85 (28%), Positives = 45/85 (52%)
 Frame = +3

Query: 352 SLTCAQFHPDGLIFGTGTMDSQIKIWDLKERTNVANFPGHSGPITSIAFSENGYYLATAA 411
           +L+  +F P+G    + + D  IKIW   +        GH   ++ +A+S +   L +A+
Sbjct: 192 ALSAVKFSPNGDWLASSSADKLIKIWGAYDGKFEKTIAGHKLGLSDVAWSSDSKLLCSAS 371

Query: 412 DDSSVKLWDLRKLKNFKTLQLDNNF 436
           DD ++K+W+    K  KTL+  +N+
Sbjct: 372 DDKTLKIWEFSTGKCMKTLKGHSNY 446

 Score = 41.6 bits (96), Expect = 8e-04,   Method: Compositional matrix adjust.
 Identities = 20/84 (23%), Positives = 42/84 (50%)
 Frame = +3

Query: 242 ADKNVVVFDKSTEQILATLKGHTKKVTSVVFHPSQELVFSASPDATIRIWSVPNTSCVQV 301
           ADK + ++     +   T+ GH   ++ V +    +L+ SAS D T++IW      C++ 
Sbjct: 246 ADKLIKIWGAYDGKFEKTIAGHKLGLSDVAWSSDSKLLCSASDDKTLKIWEFSTGKCMKT 425

Query: 302 VRAHESAVTGLSLHATGDYLLSSS 325
           ++ H + V   + +   + ++S S
Sbjct: 426 LKGHSNYVFCCNFNPQSNLIVSGS 497

 Score = 36.2 bits (82), Expect = 0.035,   Method: Compositional matrix adjust.
 Identities = 17/52 (32%), Positives = 29/52 (55%)
 Frame = +3

Query: 232 SDTNKILTGGADKNVVVFDKSTEQILATLKGHTKKVTSVVFHPSQELVFSAS 283
           SD+  + +   DK + +++ ST + + TLKGH+  V    F+P   L+ S S
Sbjct: 342 SDSKLLCSASDDKTLKIWEFSTGKCMKTLKGHSNYVFCCNFNPQSNLIVSGS 497

 Score = 32.0 bits (71), Expect = 0.56,   Method: Compositional matrix adjust.
 Identities = 26/93 (27%), Positives = 45/93 (48%), Gaps = 2/93 (2%)
 Frame = +3

Query: 340 VLTKVTDETSGCSLTCA--QFHPDGLIFGTGTMDSQIKIWDLKERTNVANFPGHSGPITS 397
           +LT  T+E+ G     A  +  P     GT +  +Q   + LK         GH+  +++
Sbjct: 39  LLTMSTEESRGAGGDTADGKHAPASATSGTKSSATQKPTYTLK-----FTLAGHTKALSA 203

Query: 398 IAFSENGYYLATAADDSSVKLWDLRKLKNFKTL 430
           + FS NG +LA+++ D  +K+W     K  KT+
Sbjct: 204 VKFSPNGDWLASSSADKLIKIWGAYDGKFEKTI 302
>21105
          Length = 650

 Score = 52.0 bits (123), Expect = 6e-07,   Method: Compositional matrix adjust.
 Identities = 24/94 (25%), Positives = 51/94 (54%), Gaps = 4/94 (4%)
 Frame = +1

Query: 238 LTGGADKNVVVFDKSTEQILATLKGHTKKVTSVVFHPSQELVFSASPDATIRIWSVPNTS 297
           +T   D+++  FD +T +++  +  H   VTS+   P+   + S S D +IR+W++ + +
Sbjct: 112 ITAHEDRHIRFFDNNTGKLIHAMVAHLDSVTSLAVDPNGLYLLSGSHDCSIRLWNLDSKT 291

Query: 298 CVQVVRAH----ESAVTGLSLHATGDYLLSSSDD 327
           CVQ + +H    + ++  ++ H    Y+ S+  D
Sbjct: 292 CVQEITSHRKKFDESIHDVAFHPQKPYIASAGAD 393

 Score = 44.7 bits (104), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 28/109 (25%), Positives = 52/109 (47%), Gaps = 4/109 (3%)
 Frame = +1

Query: 315 HATGDYLLSSSDDQYWAFSDIQTGRVLTKVTDETSGCSLTCAQFHPDGLIFGTGTMDSQI 374
           H T    +++ +D++  F D  TG+++  +       S+T     P+GL   +G+ D  I
Sbjct: 91  HPTMPITITAHEDRHIRFFDNNTGKLIHAMVAHLD--SVTSLAVDPNGLYLLSGSHDCSI 264

Query: 375 KIWDLKERTNVANFPGHSGP----ITSIAFSENGYYLATAADDSSVKLW 419
           ++W+L  +T V     H       I  +AF     Y+A+A  D+  K++
Sbjct: 265 RLWNLDSKTCVQEITSHRKKFDESIHDVAFHPQKPYIASAGADALAKVF 411
>27465
          Length = 658

 Score = 51.2 bits (121), Expect = 8e-07,   Method: Compositional matrix adjust.
 Identities = 25/104 (24%), Positives = 52/104 (50%), Gaps = 1/104 (0%)
 Frame = -1

Query: 237 ILTGGADKNVVVFDKSTEQILATLKGHTKKVTSVVFH-PSQELVFSASPDATIRIWSVPN 295
            +TG  D+   ++D ++ + L TL+GH   V ++ F+ P  + V + S D T ++WS  +
Sbjct: 316 FITGSYDRTCKIWDTASAEELHTLEGHRNVVYAIAFNNPFGDKVITGSFDKTCKLWSTAD 137

Query: 296 TSCVQVVRAHESAVTGLSLHATGDYLLSSSDDQYWAFSDIQTGR 339
             C   +R H + +  +S + +   + + S D      D++  +
Sbjct: 136 GKCYHTLRGHTAEIVCVSFNPSSTLIATGSMDTTCRLWDVEKAQ 5

 Score = 48.9 bits (115), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 21/59 (35%), Positives = 35/59 (59%)
 Frame = -1

Query: 235 NKILTGGADKNVVVFDKSTEQILATLKGHTKKVTSVVFHPSQELVFSASPDATIRIWSV 293
           +K++TG  DK   ++  +  +   TL+GHT ++  V F+PS  L+ + S D T R+W V
Sbjct: 193 DKVITGSFDKTCKLWSTADGKCYHTLRGHTAEIVCVSFNPSSTLIATGSMDTTCRLWDV 17

 Score = 45.8 bits (107), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 29/124 (23%), Positives = 56/124 (45%)
 Frame = -1

Query: 300 QVVRAHESAVTGLSLHATGDYLLSSSDDQYWAFSDIQTGRVLTKVTDETSGCSLTCAQFH 359
           +V+RAH   +T ++ + +G   ++ S D+     D  +   L  +           A  +
Sbjct: 379 KVLRAHILPLTNVAFNKSGSSFITGSYDRTCKIWDTASAEELHTLEGH-RNVVYAIAFNN 203

Query: 360 PDGLIFGTGTMDSQIKIWDLKERTNVANFPGHSGPITSIAFSENGYYLATAADDSSVKLW 419
           P G    TG+ D   K+W   +        GH+  I  ++F+ +   +AT + D++ +LW
Sbjct: 202 PFGDKVITGSFDKTCKLWSTADGKCYHTLRGHTAEIVCVSFNPSSTLIATGSMDTTCRLW 23

Query: 420 DLRK 423
           D+ K
Sbjct: 22  DVEK 11

 Score = 38.9 bits (89), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 30/121 (24%), Positives = 55/121 (45%), Gaps = 6/121 (4%)
 Frame = -1

Query: 390 GHSGPITSIAFSENGYYLATAADDSSVKLWDLRKLKNFKTLQLDNNFEVKSLIFDQS-GT 448
            H  P+T++AF+++G    T + D + K+WD    +   TL+   N  V ++ F+   G 
Sbjct: 367 AHILPLTNVAFNKSGSSFITGSYDRTCKIWDTASAEELHTLEGHRNV-VYAIAFNNPFGD 191

Query: 449 YLALGGTDVQIYICKQWT----EILH-FTEHSGLTTGVAFGHHAKFIASTGMDRSLKFYS 503
            +  G  D     CK W+    +  H    H+     V+F   +  IA+  MD + + + 
Sbjct: 190 KVITGSFD---KTCKLWSTADGKCYHTLRGHTAEIVCVSFNPSSTLIATGSMDTTCRLWD 20

Query: 504 L 504
           +
Sbjct: 19  V 17
>19140
          Length = 573

 Score = 51.2 bits (121), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 32/95 (33%), Positives = 43/95 (45%), Gaps = 1/95 (1%)
 Frame = -3

Query: 244 KNVVVFDKSTEQILATLKGHTKKVTSVVFHPSQELVFSASPDATIRIWSVPNTSCVQVVR 303
           K+       T   L  LKGHT  V ++V +       S S D TIR+WS+    CV   R
Sbjct: 547 KSSACLGPRTCHKLMKLKGHTDNVKALVLNRDGTQCLSGSSDGTIRLWSLGQQRCVATFR 368

Query: 304 AHESAVTGLSLHATGDYLLSSSDD-QYWAFSDIQT 337
            H+  V  L  + +   L S   D Q WA +DI+ 
Sbjct: 367 VHDEGVWALQANESFTTLYSGGRDHQVWA-TDIKN 266

 Score = 34.7 bits (78), Expect = 0.10,   Method: Compositional matrix adjust.
 Identities = 17/71 (23%), Positives = 39/71 (54%)
 Frame = -3

Query: 390 GHSGPITSIAFSENGYYLATAADDSSVKLWDLRKLKNFKTLQLDNNFEVKSLIFDQSGTY 449
           GH+  + ++  + +G    + + D +++LW L + +   T ++ ++  V +L  ++S T 
Sbjct: 493 GHTDNVKALVLNRDGTQCLSGSSDGTIRLWSLGQQRCVATFRV-HDEGVWALQANESFTT 317

Query: 450 LALGGTDVQIY 460
           L  GG D Q++
Sbjct: 316 LYSGGRDHQVW 284
>37180
          Length = 681

 Score = 50.8 bits (120), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 22/75 (29%), Positives = 44/75 (58%), Gaps = 1/75 (1%)
 Frame = +1

Query: 353 LTCAQFHPDGLIFGTGTMDSQIKIWDLKERTNVAN-FPGHSGPITSIAFSENGYYLATAA 411
           L+    HP   +  T + D   ++WD ++   + N F GH+ P+TS  F+ +G  + + +
Sbjct: 28  LSDVHAHPTQRLVVTSSKDMTFRLWDFRDSALLVNVFQGHTQPVTSAVFA-SGDKVVSGS 204

Query: 412 DDSSVKLWDLRKLKN 426
           DD +V++WD+R +++
Sbjct: 205 DDRTVRVWDMRNMRS 249

 Score = 50.1 bits (118), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 28/81 (34%), Positives = 48/81 (59%), Gaps = 1/81 (1%)
 Frame = +1

Query: 260 LKGHTKKVTSVVFHPSQELVFSASPDATIRIWSVPNTS-CVQVVRAHESAVTGLSLHATG 318
           L GH ++++ V  HP+Q LV ++S D T R+W   +++  V V + H   VT  ++ A+G
Sbjct: 7   LNGHDQELSDVHAHPTQRLVVTSSKDMTFRLWDFRDSALLVNVFQGHTQPVTS-AVFASG 183

Query: 319 DYLLSSSDDQYWAFSDIQTGR 339
           D ++S SDD+     D++  R
Sbjct: 184 DKVVSGSDDRTVRVWDMRNMR 246

 Score = 37.4 bits (85), Expect = 0.016,   Method: Compositional matrix adjust.
 Identities = 20/60 (33%), Positives = 34/60 (56%), Gaps = 1/60 (1%)
 Frame = +1

Query: 237 ILTGGADKNVVVFD-KSTEQILATLKGHTKKVTSVVFHPSQELVFSASPDATIRIWSVPN 295
           ++T   D    ++D + +  ++   +GHT+ VTS VF  S + V S S D T+R+W + N
Sbjct: 64  VVTSSKDMTFRLWDFRDSALLVNVFQGHTQPVTSAVF-ASGDKVVSGSDDRTVRVWDMRN 240
>00825
          Length = 1821

 Score = 50.1 bits (118), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 38/146 (26%), Positives = 63/146 (43%), Gaps = 4/146 (2%)
 Frame = -2

Query: 281  SASPDATIRIWSVPNTSCVQVVRAHESAVTGLSLHATGDYLLSSSDD---QYWAFSDIQT 337
            S + D  +  W++P       V+AH+  V G++ H++G Y  S   D   + W+  D + 
Sbjct: 1820 SGACDGELICWNLPKQQMACRVQAHDGIVHGMAAHSSGQYFFSCGSDKTIKQWSL-DPEG 1644

Query: 338  GRVLTKVTDETSGCSLTCAQFHPDGLIFGTGTMDSQIKIWDLKERTNVANFPGHSGPITS 397
                  V    + C  T    H    IF T    S++ +WD K    + +F      +  
Sbjct: 1643 TIAPEPVNTLLAKCIYTSLDHHWKDDIFVTSG--SRVDVWDEKRSEPMRSFSWGVESVHH 1470

Query: 398  IAFSE-NGYYLATAADDSSVKLWDLR 422
            + F+    Y L  AA D S+ L+D+R
Sbjct: 1469 VKFNPVETYLLGAAAHDRSILLYDMR 1392

 Score = 42.0 bits (97), Expect = 6e-04,   Method: Compositional matrix adjust.
 Identities = 23/86 (26%), Positives = 46/86 (53%), Gaps = 2/86 (2%)
 Frame = -2

Query: 208  RQVASHVGLHSASIPGILALDLCPSDTNKILTGGADKNVVVF--DKSTEQILATLKGHTK 265
            R+++  + +H      ++ +D CP+   + ++ G DK + +F  DK   + +   K   +
Sbjct: 1268 RKLSMPLNMHRDHTAAVMDVDYCPT-GREFVSAGYDKVIRIFPVDKGHSREVYHTK-RMQ 1095

Query: 266  KVTSVVFHPSQELVFSASPDATIRIW 291
            +V SVV+    + +FSAS +  IR+W
Sbjct: 1094 RVGSVVWSRDSKYIFSASDEMNIRVW 1017
>15780
          Length = 735

 Score = 48.9 bits (115), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 21/71 (29%), Positives = 39/71 (54%)
 Frame = -1

Query: 365 FGTGTMDSQIKIWDLKERTNVANFPGHSGPITSIAFSENGYYLATAADDSSVKLWDLRKL 424
             T   D  + +WD+   T VA+   H+  + ++ FS +G  LA+   D+S++LWDL ++
Sbjct: 729 LSTAGADHTVIVWDIASGTAVAHLTAHTDTVYALCFSRDGTVLASGGMDNSIRLWDLARV 550

Query: 425 KNFKTLQLDNN 435
              +  + D+N
Sbjct: 549 MEEQDPETDSN 517

 Score = 37.7 bits (86), Expect = 0.010,   Method: Compositional matrix adjust.
 Identities = 18/55 (32%), Positives = 30/55 (54%)
 Frame = -1

Query: 239 TGGADKNVVVFDKSTEQILATLKGHTKKVTSVVFHPSQELVFSASPDATIRIWSV 293
           T GAD  V+V+D ++   +A L  HT  V ++ F     ++ S   D +IR+W +
Sbjct: 723 TAGADHTVIVWDIASGTAVAHLTAHTDTVYALCFSRDGTVLASGGMDNSIRLWDL 559

 Score = 34.3 bits (77), Expect = 0.12,   Method: Compositional matrix adjust.
 Identities = 17/58 (29%), Positives = 27/58 (46%), Gaps = 2/58 (3%)
 Frame = -1

Query: 449 YLALGGTD--VQIYICKQWTEILHFTEHSGLTTGVAFGHHAKFIASTGMDRSLKFYSL 504
           YL+  G D  V ++     T + H T H+     + F      +AS GMD S++ + L
Sbjct: 732 YLSTAGADHTVIVWDIASGTAVAHLTAHTDTVYALCFSRDGTVLASGGMDNSIRLWDL 559
>12960
          Length = 550

 Score = 48.9 bits (115), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 23/65 (35%), Positives = 35/65 (53%)
 Frame = +2

Query: 233 DTNKILTGGADKNVVVFDKSTEQILATLKGHTKKVTSVVFHPSQELVFSASPDATIRIWS 292
           D ++I +GG DK VV+FD ++ Q L   + H   V  V F+    ++ S S D T+R W 
Sbjct: 332 DNSQICSGGIDKTVVLFDVASGQALRKYRDHAGTVNCVKFNEESTVILSGSLDNTVRAWD 511

Query: 293 VPNTS 297
             + S
Sbjct: 512 TRSRS 526

 Score = 35.8 bits (81), Expect = 0.039,   Method: Compositional matrix adjust.
 Identities = 25/110 (22%), Positives = 47/110 (42%), Gaps = 2/110 (1%)
 Frame = +2

Query: 395 ITSIAFSENGYYLATAADDSSVKLWDLRKLKNFKTLQLDNNFEVKSLIFDQSGTYLALGG 454
           + ++ FS +  Y  T   D SVKLW+  +    KT  + +  EV         + +  GG
Sbjct: 182 VRAVRFSVDSRYCMTCGSDKSVKLWNPHRELFLKTY-IGHGHEVLDAQGSGDNSQICSGG 358

Query: 455 TD--VQIYICKQWTEILHFTEHSGLTTGVAFGHHAKFIASTGMDRSLKFY 502
            D  V ++       +  + +H+G    V F   +  I S  +D +++ +
Sbjct: 359 IDKTVVLFDVASGQALRKYRDHAGTVNCVKFNEESTVILSGSLDNTVRAW 508

 Score = 35.4 bits (80), Expect = 0.058,   Method: Compositional matrix adjust.
 Identities = 15/67 (22%), Positives = 33/67 (49%)
 Frame = +2

Query: 356 AQFHPDGLIFGTGTMDSQIKIWDLKERTNVANFPGHSGPITSIAFSENGYYLATAADDSS 415
           AQ   D     +G +D  + ++D+     +  +  H+G +  + F+E    + + + D++
Sbjct: 317 AQGSGDNSQICSGGIDKTVVLFDVASGQALRKYRDHAGTVNCVKFNEESTVILSGSLDNT 496

Query: 416 VKLWDLR 422
           V+ WD R
Sbjct: 497 VRAWDTR 517
>20662
          Length = 1220

 Score = 48.5 bits (114), Expect = 7e-06,   Method: Compositional matrix adjust.
 Identities = 46/176 (26%), Positives = 78/176 (44%), Gaps = 8/176 (4%)
 Frame = +2

Query: 233 DTNKILTGGADKNVVVFDKSTEQ----ILATLKGHTKKVTSVVFHPSQELVFSASPDATI 288
           D++K+L G     V +++   E     +L++   H     SV  +       SAS D  I
Sbjct: 281 DSHKVLVGLDTGGVALWELQDEDKMFSMLSSACEHDDMTASVSINSDXSHYLSASYDHGI 460

Query: 289 RIWSVPNTSCVQVVRAHESAVTGLSLHATGDYL-LSSSDDQYWAFSDIQTGRVLTKVTDE 347
           ++W+   TS +   RAH   V  +  H T   L LS S D      D++  +  T +   
Sbjct: 461 KVWNTDLTS-LYTYRAHSDIVWDVQCHPTEPALFLSCSQDGKIVLWDVRESKPATCLPKC 637

Query: 348 TSGCSLTCAQFHPDGL-IFGTGTMDSQIKIWDLKE--RTNVANFPGHSGPITSIAF 400
           +SG   TC Q+ P+   ++  G     + + DL+     NV+ +  H+  +T +AF
Sbjct: 638 SSGFKPTCVQWQPNARNMYAVGDEGGHVSVQDLRMVVEKNVS-YQSHNRVVTRLAF 802
>01768
          Length = 1424

 Score = 47.8 bits (112), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 37/122 (30%), Positives = 64/122 (52%), Gaps = 12/122 (9%)
 Frame = +3

Query: 352 SLTCAQFHPD-GLIFGTGTMDSQIKIWDLKERTNVANF----PGHSGPITSIAFSE-NGY 405
           S+   Q+ P+ G +F + ++D  ++IW+ +++ + AN       HS  I  I ++    +
Sbjct: 843 SVEDVQWSPNEGNVFASCSVDRTLRIWNTQQKPSKANVLTVPEAHSRDINVINWNPIEKH 1022

Query: 406 YLATAADDSSVKLWDLRKLKNFKTLQLDNNFE-----VKSLIFD-QSGTYLALGGTDVQI 459
            LA+  DD  +K+WDLR  +N K +    +F+     V SL ++ Q  + LA  G D QI
Sbjct: 1023LLASGGDDGIIKIWDLRMFRN-KPVSAQASFKLHSQPVTSLEWNPQDSSVLAASGEDDQI 1199

Query: 460 YI 461
            I
Sbjct: 1200TI 1205
>16105
          Length = 960

 Score = 47.0 bits (110), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 48/180 (26%), Positives = 73/180 (40%), Gaps = 11/180 (6%)
 Frame = -2

Query: 210 VASHVGLHSASIPGILALDLCPSDTNKILTGGADKNVVVFDKSTEQILATLK-------G 262
           VA H G        +L +  CP + N I +   D  V V+      ++  L        G
Sbjct: 587 VAGHKG-------AVLDIQWCPHNDNVIASASDDCTVKVWQIPDSGLVTNLTDPVVDLVG 429

Query: 263 HTKKVTSVVFHPS-QELVFSASPDATIRIWSVPNTSCVQVVRAHESAVTGLSLHATGDYL 321
           H K+   +V+HPS Q ++ SA  D  I  W+V     +  V   +  +  +S +  G  L
Sbjct: 428 HQKRCCLIVWHPSAQNVLVSAGADNKILFWNVGTGEPMLEVDVPD-MIYCMSFNFNGSRL 252

Query: 322 LSSSDDQYWAFSDIQTGRVLTKVTDETSGCSLTCAQFHPDGLIFGTG---TMDSQIKIWD 378
           + +  D+     D  +G VL K      G     A +  DG +F TG     + Q  IWD
Sbjct: 251 VCTCKDKKLRIIDSHSGAVL-KEGKCHDGAKPAQACYLKDGKVFTTGFSRMSERQYAIWD 75

 Score = 33.9 bits (76), Expect = 0.16,   Method: Compositional matrix adjust.
 Identities = 38/185 (20%), Positives = 75/185 (40%), Gaps = 13/185 (7%)
 Frame = -2

Query: 260 LKGHTKKVTSVVFHP-SQELVFSASPDATIRIWSVPNTSCVQVVR-------AHESAVTG 311
           + GH   V  + + P +  ++ SAS D T+++W +P++  V  +         H+     
Sbjct: 587 VAGHKGAVLDIQWCPHNDNVIASASDDCTVKVWQIPDSGLVTNLTDPVVDLVGHQKRCCL 408

Query: 312 LSLHATG-DYLLSSSDDQYWAFSDIQTGRVLTKVTDETSGCSLTCAQFHPDGLIFGTGTM 370
           +  H +  + L+S+  D    F ++ TG  + +V        + C  F+ +G        
Sbjct: 407 IVWHPSAQNVLVSAGADNKILFWNVGTGEPMLEVDVPD---MIYCMSFNFNGSRLVCTCK 237

Query: 371 DSQIKIWDLKERTNVANFPGHSGPITSIA-FSENGYYLATAADDSSVK---LWDLRKLKN 426
           D +++I D      +     H G   + A + ++G    T     S +   +WD   L  
Sbjct: 236 DKKLRIIDSHSGAVLKEGKCHDGAKPAQACYLKDGKVFTTGFSRMSERQYAIWDENDLSE 57

Query: 427 FKTLQ 431
             TL+
Sbjct: 56  SMTLE 42
>13278
          Length = 870

 Score = 46.6 bits (109), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 18/60 (30%), Positives = 36/60 (60%)
 Frame = +1

Query: 363 LIFGTGTMDSQIKIWDLKERTNVANFPGHSGPITSIAFSENGYYLATAADDSSVKLWDLR 422
           LI  + + DS +++W+++    +     H  P+ S+AFS +G YLA+ + D  V +W+++
Sbjct: 115 LILASASFDSTVRLWEVERGLCLHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNVQ 294

 Score = 45.1 bits (105), Expect = 7e-05,   Method: Compositional matrix adjust.
 Identities = 34/152 (22%), Positives = 61/152 (40%), Gaps = 1/152 (0%)
 Frame = +1

Query: 273 HPSQELVF-SASPDATIRIWSVPNTSCVQVVRAHESAVTGLSLHATGDYLLSSSDDQYWA 331
           +P+  L+  SAS D+T+R+W V    C+  +  H+  V  ++                  
Sbjct: 100 NPNTSLILASASFDSTVRLWEVERGLCLHTLTKHQEPVYSVA------------------ 225

Query: 332 FSDIQTGRVLTKVTDETSGCSLTCAQFHPDGLIFGTGTMDSQIKIWDLKERTNVANFPGH 391
                                     F PDG    +G+ D  + IW+++  + V ++ G 
Sbjct: 226 --------------------------FSPDGKYLASGSFDKCVHIWNVQTGSLVHSYKG- 324

Query: 392 SGPITSIAFSENGYYLATAADDSSVKLWDLRK 423
           +G I  + ++  G  +  +A D SV + DLRK
Sbjct: 325 TGGIFEVCWNHRGDKVGASASDGSVFVLDLRK 420
>19863
          Length = 502

 Score = 46.2 bits (108), Expect = 3e-05,   Method: Composition-based stats.
 Identities = 17/63 (26%), Positives = 38/63 (60%)
 Frame = +1

Query: 361 DGLIFGTGTMDSQIKIWDLKERTNVANFPGHSGPITSIAFSENGYYLATAADDSSVKLWD 420
           DGL   +G+ D  I +WD++         GH+G +  + FS++  +L + ++D++V++W+
Sbjct: 4   DGLQLVSGSSDMSIVVWDVENGVQKLRLQGHAGWVNDVHFSQDQCWLLSCSNDNTVRIWN 183

Query: 421 LRK 423
           + +
Sbjct: 184 IEE 192

 Score = 44.3 bits (103), Expect = 1e-04,   Method: Composition-based stats.
 Identities = 23/76 (30%), Positives = 40/76 (52%)
 Frame = +1

Query: 233 DTNKILTGGADKNVVVFDKSTEQILATLKGHTKKVTSVVFHPSQELVFSASPDATIRIWS 292
           D  ++++G +D ++VV+D         L+GH   V  V F   Q  + S S D T+RIW+
Sbjct: 4   DGLQLVSGSSDMSIVVWDVENGVQKLRLQGHAGWVNDVHFSQDQCWLLSCSNDNTVRIWN 183

Query: 293 VPNTSCVQVVRAHESA 308
           +  +  + +V  H+ A
Sbjct: 184 IEESDQIPIVMEHKRA 231
>18981
          Length = 407

 Score = 45.4 bits (106), Expect = 5e-05,   Method: Composition-based stats.
 Identities = 27/107 (25%), Positives = 53/107 (49%)
 Frame = -2

Query: 273 HPSQELVFSASPDATIRIWSVPNTSCVQVVRAHESAVTGLSLHATGDYLLSSSDDQYWAF 332
           H    ++ SA+ D T+R+W + NT  +  +R H   V  + ++  G  ++S S D+    
Sbjct: 397 HLLDNMIISAATDRTLRVWCLKNTCLLHTLRGHNDDVECVCIY--GRRVVSGSWDKTLIV 224

Query: 333 SDIQTGRVLTKVTDETSGCSLTCAQFHPDGLIFGTGTMDSQIKIWDL 379
            ++ TGR + ++   T   ++T  QF     +  +G+ D  ++ W L
Sbjct: 223 WEVDTGRPVHQLHGHTE--AITAVQFDEGKAV--SGSADGDVRTWAL 95
>31054
          Length = 392

 Score = 45.1 bits (105), Expect = 7e-05,   Method: Compositional matrix adjust.
 Identities = 29/107 (27%), Positives = 50/107 (46%), Gaps = 7/107 (6%)
 Frame = -2

Query: 365 FGTGTMDSQIKIWDLKERTNVANFPGHSGPITSIAFSENGYYLATAADDSSVKLWDLRKL 424
           F  G+ D  +K W   +   + N  GH+  I ++A + +G  L + AD+ ++ LWD R  
Sbjct: 367 FAXGSPDX-VKQWKFPDGNFIQNLSGHNAIINTLAVNSDG-VLVSGADNGTMHLWDWRTG 194

Query: 425 KNFKTLQ-------LDNNFEVKSLIFDQSGTYLALGGTDVQIYICKQ 464
            NF+ +        LD+     +  FDQS + L     D  I + ++
Sbjct: 193 YNFQRIHAAVQPGSLDSESGFFACTFDQSESRLITAEADKTIKVYRE 53
>26939
          Length = 388

 Score = 44.7 bits (104), Expect = 8e-05,   Method: Composition-based stats.
 Identities = 19/48 (39%), Positives = 28/48 (58%)
 Frame = +2

Query: 281 SASPDATIRIWSVPNTSCVQVVRAHESAVTGLSLHATGDYLLSSSDDQ 328
           SAS D TIR+W + N  C++ + AH+   T +  H    Y++S S DQ
Sbjct: 17  SASDDKTIRVWDLRNKRCMKTLYAHQHFCTSIDFHKAHPYVISGSVDQ 160

 Score = 42.0 bits (97), Expect = 5e-04,   Method: Composition-based stats.
 Identities = 21/62 (33%), Positives = 37/62 (59%), Gaps = 2/62 (3%)
 Frame = +2

Query: 404 GYYLATAADDSSVKLWDLRKLKNFKTLQLDNNFEVKSLIFDQSGTYLALGGTD--VQIYI 461
           G YL +A+DD ++++WDLR  +  KTL    +F   S+ F ++  Y+  G  D  V+++ 
Sbjct: 2   GKYLVSASDDKTIRVWDLRNKRCMKTLYAHQHF-CTSIDFHKAHPYVISGSVDQTVKVWE 178

Query: 462 CK 463
           C+
Sbjct: 179 CR 184

 Score = 40.0 bits (92), Expect = 0.002,   Method: Composition-based stats.
 Identities = 17/55 (30%), Positives = 30/55 (54%)
 Frame = +2

Query: 237 ILTGGADKNVVVFDKSTEQILATLKGHTKKVTSVVFHPSQELVFSASPDATIRIW 291
           +++   DK + V+D   ++ + TL  H    TS+ FH +   V S S D T+++W
Sbjct: 11  LVSASDDKTIRVWDLRNKRCMKTLYAHQHFCTSIDFHKAHPYVISGSVDQTVKVW 175

 Score = 38.1 bits (87), Expect = 0.008,   Method: Composition-based stats.
 Identities = 16/52 (30%), Positives = 28/52 (53%)
 Frame = +2

Query: 371 DSQIKIWDLKERTNVANFPGHSGPITSIAFSENGYYLATAADDSSVKLWDLR 422
           D  I++WDL+ +  +     H    TSI F +   Y+ + + D +VK+W+ R
Sbjct: 29  DKTIRVWDLRNKRCMKTLYAHQHFCTSIDFHKAHPYVISGSVDQTVKVWECR 184

 Score = 33.1 bits (74), Expect = 0.29,   Method: Composition-based stats.
 Identities = 17/63 (26%), Positives = 31/63 (49%)
 Frame = +2

Query: 318 GDYLLSSSDDQYWAFSDIQTGRVLTKVTDETSGCSLTCAQFHPDGLIFGTGTMDSQIKIW 377
           G YL+S+SDD+     D++  R +  +      C  T   FH       +G++D  +K+W
Sbjct: 2   GKYLVSASDDKTIRVWDLRNKRCMKTLYAHQHFC--TSIDFHKAHPYVISGSVDQTVKVW 175

Query: 378 DLK 380
           + +
Sbjct: 176 ECR 184
>02960
          Length = 1577

 Score = 44.3 bits (103), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 59/270 (21%), Positives = 104/270 (38%), Gaps = 47/270 (17%)
 Frame = +2

Query: 280 FSASPDATIRIWS--------VPN----TSCVQVVRAHESAVTGLSLHATGDYLLSSSDD 327
            S S D T+R+WS        +P       CV  ++  ES+  G+S   TG      S D
Sbjct: 527 LSGSYDNTVRLWSTKGEAIMTIPGHTSPVKCVAWIKHDESS--GVSTFVTG------SHD 682

Query: 328 Q---YWAFSDIQTGRVLTKVTDETSGCSLTCAQFHPDGLIFGTGTMDSQIKIWD------ 378
           Q    W +   +T  V  +++      S+ C    PD     TG+ D  +K+W       
Sbjct: 683 QTALVWQWQR-ETNEVDCRLSCRGHAASVDCVAVSPDSQQMCTGSWDKMLKLWSTDCNVD 859

Query: 379 --------------------LKERTNVANFPGHSGPITSIAFSENGYYLATAADDSSVKL 418
                                + R  V    GH+  ++++ + +  + + T++ D S++L
Sbjct: 860 GDQSEDTERPSKKKKSAKSTTQTRVPVLTLSGHAEAVSAVRWLDP-HRVVTSSWDHSLRL 1036

Query: 419 WDLRKLKNFKTLQLDNNFEVKSLIFDQSGTYLALGGTDVQIYI----CKQWTEI-LHFTE 473
           WDL   +    +Q   +  V  + +      L  G  D  + +    C +   +   FT 
Sbjct: 1037WDLHTAQQTSLIQ--GSKAVLDVAYSPLSHMLITGSADRHVRLVDPRCSEGETVKCAFTS 1210

Query: 474 HSGLTTGVAFGHHAKFIASTG-MDRSLKFY 502
           H+G  TGV +    + +  +G  D  LK +
Sbjct: 1211HTGWVTGVDWSPTREHLFLSGSYDNVLKLW 1300

 Score = 37.7 bits (86), Expect = 0.012,   Method: Compositional matrix adjust.
 Identities = 61/268 (22%), Positives = 108/268 (40%), Gaps = 38/268 (14%)
 Frame = +2

Query: 232 SDTNKILTGGADKNVVVFD--KSTEQILATL--KGHTKKVTSVVFHPSQELVFSASPDAT 287
           S  +  +TG  D+  +V+   + T ++   L  +GH   V  V   P  + + + S D  
Sbjct: 647 SGVSTFVTGSHDQTALVWQWQRETNEVDCRLSCRGHAASVDCVAVSPDSQQMCTGSWDKM 826

Query: 288 IRIWSVPNTSC-----------------------------VQVVRAHESAVTGLSLHATG 318
           +++WS   T C                             V  +  H  AV+ +      
Sbjct: 827 LKLWS---TDCNVDGDQSEDTERPSKKKKSAKSTTQTRVPVLTLSGHAEAVSAVRW-LDP 994

Query: 319 DYLLSSSDDQYWAFSDIQTGRVLTKVTDETSGCSLTCAQFHPDGLIFGTGTMDSQIKIWD 378
             +++SS D      D+ T +  + +  + S   L  A + P   +  TG+ D  +++ D
Sbjct: 995 HRVVTSSWDHSLRLWDLHTAQQTSLI--QGSKAVLDVA-YSPLSHMLITGSADRHVRLVD 1165

Query: 379 LK---ERTNVANFPGHSGPITSIAFSENGYYL-ATAADDSSVKLWDLRKLKNFKTLQLDN 434
            +     T    F  H+G +T + +S    +L  + + D+ +KLWD R  K   TL   N
Sbjct: 1166PRCSEGETVKCAFTSHTGWVTGVDWSPTREHLFLSGSYDNVLKLWDTRSPK--ATLYDMN 1339

Query: 435 NFEVKSLIFDQSGTYLAL-GGTDVQIYI 461
             E + L  D S   L L GG D ++++
Sbjct: 1340WHEDRILAVDWSIPELLLSGGVDNKLHV 1423
>27806
          Length = 419

 Score = 43.9 bits (102), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 21/55 (38%), Positives = 28/55 (50%)
 Frame = -1

Query: 237 ILTGGADKNVVVFDKSTEQILATLKGHTKKVTSVVFHPSQELVFSASPDATIRIW 291
           I T  AD    ++   T   + T  GH   V +V FHP Q+LV +AS D T  +W
Sbjct: 380 IGTASADHTARIYSIETGACVLTYGGHQGSVNAVRFHPGQDLVLTASGDHTAHVW 216
>31384
          Length = 474

 Score = 43.9 bits (102), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 23/87 (26%), Positives = 48/87 (55%), Gaps = 5/87 (5%)
 Frame = -1

Query: 352 SLTCAQFHPDGL---IFGTGTMDSQIKIWDLKE--RTNVANFPGHSGPITSIAFSENGYY 406
           S++C +F P  L      +G+ D+++  W++++  +T       H+GP+  + +S++G  
Sbjct: 270 SVSCLKFSPGALPSTFLISGSWDNKVSCWEVQQSGQTIPKAQQTHTGPVLDVDWSDDGTK 91

Query: 407 LATAADDSSVKLWDLRKLKNFKTLQLD 433
           + TA+ D + K+WDL   +  +  Q D
Sbjct: 90  VFTASCDKTAKVWDLNSNQCMQIAQHD 10

 Score = 33.9 bits (76), Expect = 0.15,   Method: Compositional matrix adjust.
 Identities = 20/75 (26%), Positives = 39/75 (52%), Gaps = 2/75 (2%)
 Frame = -1

Query: 237 ILTGGADKNVVVFD--KSTEQILATLKGHTKKVTSVVFHPSQELVFSASPDATIRIWSVP 294
           +++G  D  V  ++  +S + I    + HT  V  V +      VF+AS D T ++W + 
Sbjct: 222 LISGSWDNKVSCWEVQQSGQTIPKAQQTHTGPVLDVDWSDDGTKVFTASCDKTAKVWDLN 43

Query: 295 NTSCVQVVRAHESAV 309
           +  C+Q+ + H++ V
Sbjct: 42  SNQCMQIAQ-HDAPV 1
>15745
          Length = 1183

 Score = 43.5 bits (101), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 24/74 (32%), Positives = 36/74 (48%), Gaps = 3/74 (4%)
 Frame = +2

Query: 353 LTCAQFHPDGLIFGTGTMD-SQIKIWDLKERTNVANFPG-HSGPITSIAFSEN-GYYLAT 409
           LTC +++P        T + + I+ WDL+ +       G H   +  + F+ N  YYLA+
Sbjct: 587 LTCGRWNPHHNCAQIATANEATIRGWDLRSKQQTYQMEGAHGQLVRDLDFNPNRQYYLAS 766

Query: 410 AADDSSVKLWDLRK 423
             DD  VK WD R 
Sbjct: 767 CGDDCRVKFWDTRN 808
>01462
          Length = 995

 Score = 42.4 bits (98), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 18/60 (30%), Positives = 30/60 (50%)
 Frame = +2

Query: 234 TNKILTGGADKNVVVFDKSTEQILATLKGHTKKVTSVVFHPSQELVFSASPDATIRIWSV 293
           T ++  G  D+ + V+D    Q L  ++GH   +  VV     +   SAS D T+R+W +
Sbjct: 233 TRRLYAGAGDRKIHVWDIEAGQYLNAMEGHKDYIHKVVMKNDAQECVSASEDGTVRMWDI 412

 Score = 37.4 bits (85), Expect = 0.013,   Method: Compositional matrix adjust.
 Identities = 14/55 (25%), Positives = 28/55 (50%)
 Frame = +2

Query: 368 GTMDSQIKIWDLKERTNVANFPGHSGPITSIAFSENGYYLATAADDSSVKLWDLR 422
           G  D +I +WD++    +    GH   I  +    +     +A++D +V++WD+R
Sbjct: 251 GAGDRKIHVWDIEAGQYLNAMEGHKDYIHKVVMKNDAQECVSASEDGTVRMWDIR 415
>01249
          Length = 1743

 Score = 42.0 bits (97), Expect = 6e-04,   Method: Compositional matrix adjust.
 Identities = 38/138 (27%), Positives = 61/138 (44%), Gaps = 15/138 (10%)
 Frame = -1

Query: 300  QVVRAHESAVTGLSLHATG--DYLLSSSDDQYWAFSDIQTGRVLTKVTDETS-GCSLTCA 356
            + + AH   +TGL +   G    + SSS D      D+ +G +L  +  ET  GC +   
Sbjct: 1230 RTINAHSEPITGLHVGCGGPAARVASSSSDGTCKLWDMLSGALLRTMVYETGVGCLIMDK 1051

Query: 357  QFHPDGLIFGTGTMD----------SQIKIWDLKERTNVAN--FPGHSGPITSIAFSENG 404
            Q H   L+ G    D          SQ +++  K  T        GHS  +T +AFS +G
Sbjct: 1050 QEHF--LLAGLDNGDILCSPLFGQISQSEVFVSKHTTKAGERVLQGHSDAVTCLAFSSDG 877

Query: 405  YYLATAADDSSVKLWDLR 422
              LA+ + +  V +W++ 
Sbjct: 876  QRLASGSQNGKVIIWNME 823

 Score = 30.8 bits (68), Expect = 1.4,   Method: Compositional matrix adjust.
 Identities = 25/115 (21%), Positives = 52/115 (45%), Gaps = 13/115 (11%)
 Frame = -1

Query: 279  VFSASPDATIRIWSVPNTSCVQVVRAHESAVTGLSLHATGDYLLSSSDD----------- 327
            V S+S D T ++W + + + ++ +  +E+ V  L +     +LL+  D+           
Sbjct: 1161 VASSSSDGTCKLWDMLSGALLRTM-VYETGVGCLIMDKQEHFLLAGLDNGDILCSPLFGQ 985

Query: 328  --QYWAFSDIQTGRVLTKVTDETSGCSLTCAQFHPDGLIFGTGTMDSQIKIWDLK 380
              Q   F    T +   +V    S  ++TC  F  DG    +G+ + ++ IW+++
Sbjct: 984  ISQSEVFVSKHTTKAGERVLQGHSD-AVTCLAFSSDGQRLASGSQNGKVIIWNME 823
>14555
          Length = 627

 Score = 31.2 bits (69), Expect(2) = 0.001,   Method: Compositional matrix adjust.
 Identities = 18/77 (23%), Positives = 31/77 (40%)
 Frame = -2

Query: 298 CVQVVRAHESAVTGLSLHATGDYLLSSSDDQYWAFSDIQTGRVLTKVTDETSGCSLTCAQ 357
           CVQ+   HE+ +  +  + +GD   + SDD         T R+     D    C      
Sbjct: 623 CVQMFEGHEADINCVRFYPSGDAFATGSDD--------ATCRLFDLRADREVNC------ 486

Query: 358 FHPDGLIFGTGTMDSQI 374
           +  + +IFG   +D  +
Sbjct: 485 YRKESIIFGCNAVDFSV 435

 Score = 28.5 bits (62), Expect(2) = 0.001,   Method: Compositional matrix adjust.
 Identities = 12/51 (23%), Positives = 24/51 (47%)
 Frame = -3

Query: 369 TMDSQIKIWDLKERTNVANFPGHSGPITSIAFSENGYYLATAADDSSVKLW 419
           T D  + +WD  +        GH   ++ +  S +G  L T + D ++++W
Sbjct: 409 TNDYTVNVWDALKGMRSTILYGHDNRVSCLRISPDGTSLCTGSWDYTLRIW 257

 Score = 37.0 bits (84), Expect = 0.021,   Method: Compositional matrix adjust.
 Identities = 20/70 (28%), Positives = 34/70 (48%)
 Frame = -2

Query: 385 VANFPGHSGPITSIAFSENGYYLATAADDSSVKLWDLRKLKNFKTLQLDNNFEVKSLIFD 444
           V  F GH   I  + F  +G   AT +DD++ +L+DLR  +        N +  +S+IF 
Sbjct: 620 VQMFEGHEADINCVRFYPSGDAFATGSDDATCRLFDLRADREV------NCYRKESIIFG 459

Query: 445 QSGTYLALGG 454
            +    ++ G
Sbjct: 458 CNAVDFSVSG 429
>27270
          Length = 1078

 Score = 38.1 bits (87), Expect = 0.009,   Method: Compositional matrix adjust.
 Identities = 42/163 (25%), Positives = 69/163 (42%), Gaps = 21/163 (12%)
 Frame = +2

Query: 278 LVFSASPDATIRIWSVPNTSCVQVV-RAHESAVTGLSLHATGDYLLSSSDDQYWAFSDIQ 336
           +V   S D ++ ++SV   +   ++ + H  AVT +   A G  L SSS D +    ++ 
Sbjct: 185 VVAVGSADGSVGLYSVETHTYTHMLNKGHSKAVTDMCWRADGRTLYSSSLDGHVIGWNVN 364

Query: 337 TGRVLTKVTDETSG------CSLTCAQFHPDGLIFGTGTMDSQIKIWDLKERTNVANFPG 390
           T  ++ K    TSG      C   C+      L+    T D  IK+WDL  +  +  F G
Sbjct: 365 TLHMIEKW-KATSGRHHGVHCVCLCSSSR---LL----TADHTIKMWDLTTKNVLQEFSG 520

Query: 391 HSG------PITSIAFSENG--------YYLATAADDSSVKLW 419
           HS       P+   +  +N         Y  + AA D ++ +W
Sbjct: 521 HSTEVIKLLPVLKPSSEQNDIGDSNLACYVFSAAAADRTINVW 649
>21921
          Length = 1341

 Score = 37.7 bits (86), Expect = 0.012,   Method: Compositional matrix adjust.
 Identities = 14/45 (31%), Positives = 27/45 (60%)
 Frame = -1

Query: 388 FPGHSGPITSIAFSENGYYLATAADDSSVKLWDLRKLKNFKTLQL 432
           + GH+G + SI     G +L + +DD +++ W++   +  KTLQ+
Sbjct: 495 YKGHTGIVRSICPDPTGQWLVSGSDDGTIRFWEVSSGRCMKTLQV 361

 Score = 36.2 bits (82), Expect = 0.032,   Method: Compositional matrix adjust.
 Identities = 16/43 (37%), Positives = 25/43 (58%)
 Frame = -1

Query: 261 KGHTKKVTSVVFHPSQELVFSASPDATIRIWSVPNTSCVQVVR 303
           KGHT  V S+   P+ + + S S D TIR W V +  C++ ++
Sbjct: 492 KGHTGIVRSICPDPTGQWLVSGSDDGTIRFWEVSSGRCMKTLQ 364

 Score = 28.1 bits (61), Expect = 8.9,   Method: Compositional matrix adjust.
 Identities = 45/178 (25%), Positives = 78/178 (43%), Gaps = 10/178 (5%)
 Frame = -1

Query: 186 ERKKRGKTVPEELV----KPEELSKYRQVASHVGLHSASIPGILALDLCPSDTNKILTGG 241
           +RK +    P++L+    KP++L  +    + V      I       +CP  T + L  G
Sbjct: 594 QRKMKMNVDPQDLLPKLPKPKDLRPFPTTQALVYKGHTGI----VRSICPDPTGQWLVSG 427

Query: 242 ADKNVVVF-DKSTEQILATLK-GHTKKVTSVVFHPSQELVFSASPDATIRIWSVPNTSCV 299
           +D   + F + S+ + + TL+ G    VTSV ++P+  L   A   AT+      NT+ +
Sbjct: 426 SDDGTIRFWEVSSGRCMKTLQVGGC--VTSVAWNPNPSLCVVA---ATL------NTTVL 280

Query: 300 QVVRAHESAVTGLSLHATGDYLLSSSDDQYWAFSD----IQTGRVLTKVTDETSGCSL 353
            +       +    + +  D LL +S+DQ  + S+    +   R    V D TSG  L
Sbjct: 279 LI----NPGLGDKLVVSNTDKLLLASEDQASSSSEKEQPVDWVRTELNVEDYTSGVRL 118
>26107
          Length = 1338

 Score = 37.4 bits (85), Expect = 0.013,   Method: Compositional matrix adjust.
 Identities = 43/172 (25%), Positives = 66/172 (38%), Gaps = 12/172 (6%)
 Frame = -3

Query: 232  SDTNKILTGGADKNVVVFDKSTEQILATLKGHTKKVTSVVFHPSQEL-VFSASPDATIRI 290
            S+ ++ LT   D+ V ++D  T   + T  GH   V SV   PS      S + D  I +
Sbjct: 1057 SNDSQCLTASGDQTVALWDVETTTKVTTFIGHKCSVRSVASCPSSPAQCASGARDGHIML 878

Query: 291  WSVPNTSCVQVVRAHESAVTGLSLHATGDYLLSSSDDQYWAFSDIQTGRVLTKVTDETSG 350
            W     S V   R H+       +H     +   S  Q       +  R         + 
Sbjct: 877  WD----SRVNKKREHQPCS---QVHQ----VCPQSGHQSKPAKHRRIHRAAGPKGVMDTQ 731

Query: 351  CSLTCAQFHPDGLIFGTGTMDSQIKIWDLKE-RTNVA----------NFPGH 391
             S+TC  +  D LI  +G  D  +K+WD ++  TN            ++PGH
Sbjct: 730  QSVTCVLYQTDNLIISSGANDGCVKMWDTRKWYTNTTTSLPVPVHTFDYPGH 575

 Score = 35.4 bits (80), Expect = 0.058,   Method: Compositional matrix adjust.
 Identities = 18/57 (31%), Positives = 28/57 (49%), Gaps = 1/57 (1%)
 Frame = -3

Query: 367  TGTMDSQIKIWDLKERTNVANFPGHSGPITSIAFSENG-YYLATAADDSSVKLWDLR 422
            T + D  + +WD++  T V  F GH   + S+A   +     A+ A D  + LWD R
Sbjct: 1036 TASGDQTVALWDVETTTKVTTFIGHKCSVRSVASCPSSPAQCASGARDGHIMLWDSR 866
>10162
          Length = 1629

 Score = 36.6 bits (83), Expect = 0.024,   Method: Compositional matrix adjust.
 Identities = 21/84 (25%), Positives = 34/84 (40%), Gaps = 2/84 (2%)
 Frame = +3

Query: 350 GCSLTCAQFHPDGLIFGTGTMDSQIKIWDL--KERTNVANFPGHSGPITSIAFSENGYYL 407
           G  +T  Q+H    +   GT   ++ +W +  ++ + +     H  P        NG Y+
Sbjct: 27  GSDITWLQWHGGAHVLLAGTQGGEVWLWQVPSQDYSKMKMLQSHGQPSLCGKILPNGKYV 206

Query: 408 ATAADDSSVKLWDLRKLKNFKTLQ 431
                D  VKLWDL+      T Q
Sbjct: 207 CVGYSDGVVKLWDLKTGTAVHTWQ 278

 Score = 36.2 bits (82), Expect = 0.033,   Method: Compositional matrix adjust.
 Identities = 53/279 (18%), Positives = 95/279 (34%), Gaps = 10/279 (3%)
 Frame = +3

Query: 150 QPSVVGAGEPMDLGELVGMTPEIIQKLQDKATVLTTERKKRGKTVPEELVKPEELSKYRQ 209
           QPS+ G   P      VG +  ++ KL D  T  T     +   +PEE +     S    
Sbjct: 162 QPSLCGKILPNGKYVCVGYSDGVV-KLWDLKTG-TAVHTWQHSVMPEEEMPERNSSDEED 335

Query: 210 VASHVGLHSASIPGILALDLCPSDTNKILTGGADKNVVVFDKSTEQILATL--------K 261
                         IL +D C +D   I++G AD    VF+ S+ ++ +          +
Sbjct: 336 GEEVEVEREEDTVAILCVD-CSADNALIMSGCADATAKVFNVSSGKLXSAFNCAASQDSQ 512

Query: 262 GHTKKVTSVVFHPSQELVFSASPDATIRIWSVPNTSCVQVVRAHESAVTGLSLHATGDYL 321
                V SV F P      +A+   ++++W +P TS  +    H   V  L         
Sbjct: 513 DKDNSVESVAFCPVSPYAATATNSGSVQVWDLP-TSVARHSFQHPEGVCKL--------- 662

Query: 322 LSSSDDQYWAFSDIQTGRVLTKVTDETSGCSLTCAQFHPDGLIFGTGTMDSQIKIWDLKE 381
                                              Q+     +  T  +D  +++WD + 
Sbjct: 663 -----------------------------------QWSSSTALLYTACLDGVMRVWDARS 737

Query: 382 RTNVANFPGHS--GPITSIAFSENGYYLATAADDSSVKL 418
             + A   GH+    I     + +G  L + ++D + ++
Sbjct: 738 GASKAVLTGHARNSCILDFDVTRDGTCLVSGSEDGTARV 854

 Score = 28.1 bits (61), Expect = 7.8,   Method: Compositional matrix adjust.
 Identities = 18/78 (23%), Positives = 33/78 (42%), Gaps = 8/78 (10%)
 Frame = +3

Query: 352 SLTCAQFHPDGLIFGTGTMDSQIKIWDLKERTNVANF--------PGHSGPITSIAFSEN 403
           ++ C     D  +  +G  D+  K++++      + F              + S+AF   
Sbjct: 375 AILCVDCSADNALIMSGCADATAKVFNVSSGKLXSAFNCAASQDSQDKDNSVESVAFCPV 554

Query: 404 GYYLATAADDSSVKLWDL 421
             Y ATA +  SV++WDL
Sbjct: 555 SPYAATATNSGSVQVWDL 608
>35607
          Length = 475

 Score = 36.2 bits (82), Expect = 0.029,   Method: Compositional matrix adjust.
 Identities = 28/97 (28%), Positives = 45/97 (46%)
 Frame = +2

Query: 360 PDGLIFGTGTMDSQIKIWDLKERTNVANFPGHSGPITSIAFSENGYYLATAADDSSVKLW 419
           PDG    TG +D+ ++ WDL+E   +      S  I S+ +   G +LA   + S+V++ 
Sbjct: 8   PDGTKLWTGGLDNTVRSWDLREGRQLQQHD-FSSQIFSLGYCPTGDWLAVGMESSNVEVL 184

Query: 420 DLRKLKNFKTLQLDNNFEVKSLIFDQSGTYLALGGTD 456
              K   ++ L L  +  V SL F   G +    G D
Sbjct: 185 HHSKPDKYQ-LHLHESC-VLSLKFAYCGKWFVSTGKD 289
>11493
          Length = 535

 Score = 35.8 bits (81), Expect = 0.044,   Method: Compositional matrix adjust.
 Identities = 34/166 (20%), Positives = 63/166 (37%), Gaps = 11/166 (6%)
 Frame = -2

Query: 263 HTKKVTSVVFHPSQELVFSASPDATIRIWS---------VPNTSCVQVVRAHESAVTGLS 313
           H + V +V      + V++      +++W          V    C+Q     ++ +  + 
Sbjct: 480 HGEVVCAVTISNPTKYVYTGG-KGCVKVWDISQPGNKNPVSQLDCLQ----RDNYIRSVK 316

Query: 314 LHATGDYLLSSSDDQYWAFSDIQ--TGRVLTKVTDETSGCSLTCAQFHPDGLIFGTGTMD 371
           L   G  L+   +    +  D+   T R+  ++T     C        PD  +  +   D
Sbjct: 315 LLPDGRTLIVGGEASNLSIWDLASPTPRIKAELTSAAPACYAL--AISPDSKVCFSCCSD 142

Query: 372 SQIKIWDLKERTNVANFPGHSGPITSIAFSENGYYLATAADDSSVK 417
             I +WDL     V  F GH+   + I  S +G  L T   D++V+
Sbjct: 141 GNIAVWDLHNEILVRQFQGHTDGASCIDISPDGSRLWTGGLDNTVR 4

 Score = 34.3 bits (77), Expect = 0.12,   Method: Compositional matrix adjust.
 Identities = 17/72 (23%), Positives = 35/72 (48%)
 Frame = -2

Query: 218 SASIPGILALDLCPSDTNKILTGGADKNVVVFDKSTEQILATLKGHTKKVTSVVFHPSQE 277
           +++ P   AL + P D+    +  +D N+ V+D   E ++   +GHT   + +   P   
Sbjct: 216 TSAAPACYALAISP-DSKVCFSCCSDGNIAVWDLHNEILVRQFQGHTDGASCIDISPDGS 40

Query: 278 LVFSASPDATIR 289
            +++   D T+R
Sbjct: 39  RLWTGGLDNTVR 4

 Score = 28.5 bits (62), Expect = 7.0,   Method: Compositional matrix adjust.
 Identities = 25/103 (24%), Positives = 38/103 (36%), Gaps = 3/103 (2%)
 Frame = -2

Query: 357 QFHPDGLIFGTGTMDSQIKIWDLKERTNV--ANFPGHSGPITSIAFSENGYYLATAADDS 414
           +  PDG     G   S + IWDL   T    A     +    ++A S +     +   D 
Sbjct: 318 KLLPDGRTLIVGGEASNLSIWDLASPTPRIKAELTSAAPACYALAISPDSKVCFSCCSDG 139

Query: 415 SVKLWDLRKLKNFKTLQLDNNFEVKSLI-FDQSGTYLALGGTD 456
           ++ +WDL         Q   + +  S I     G+ L  GG D
Sbjct: 138 NIAVWDLH--NEILVRQFQGHTDGASCIDISPDGSRLWTGGLD 16
>10264
          Length = 416

 Score = 35.4 bits (80), Expect = 0.049,   Method: Compositional matrix adjust.
 Identities = 19/62 (30%), Positives = 33/62 (53%), Gaps = 1/62 (1%)
 Frame = -1

Query: 359 HPDGLIFGTGTMDSQIKIWDLKERTNVANFPGHSGPITSIAFSE-NGYYLATAADDSSVK 417
           H D  +   G  D++  +WD+++ T +A F GH G + +  FS  +   + T   D+SV 
Sbjct: 212 HHDARLVSVG-YDAEAFVWDVQKGTALAQFKGHMGRLLTCQFSGLDPDLVMTGGSDASVH 36

Query: 418 LW 419
           +W
Sbjct: 35  VW 30
>04358
          Length = 2430

 Score = 35.4 bits (80), Expect = 0.049,   Method: Compositional matrix adjust.
 Identities = 43/165 (26%), Positives = 68/165 (41%), Gaps = 20/165 (12%)
 Frame = +1

Query: 239  TGGADKNVV---------VFDKSTEQILATLKGHTKKVTSVVF-HPSQELVFSASPDATI 288
            TGGAD  V          ++ +       TL GH   ++S+ F H    L+ +AS D T+
Sbjct: 1318 TGGADSLVAAASSNFMVRLYSRCRLAQTNTLTGHDDVISSIRFLHTDPGLIMTASHDHTV 1497

Query: 289  RIWSVPNTSCVQVVRAHESAVTGLSLHAT----GDYLLS-----SSDDQYWAFSDIQTGR 339
            RIW    +   +V R      T  S+ +      D +L      S+DD Y  F D +  +
Sbjct: 1498 RIWDPRASVSKEVQRFSGEQNTKCSVLSCDVNISDRVLCAGTEMSNDDAYLLFWDRRKDK 1677

Query: 340  VLTKVTDETSGCSLTCAQFHPDG-LIFGTGTMDSQIKIWDLKERT 383
            +L    D      +T   F P       TG+ D  + ++D+ + T
Sbjct: 1678 LLGCYEDSHHD-DITQVHFGPTSEKTLLTGSTDGLVNVFDVMQTT 1809
>31864
          Length = 545

 Score = 35.4 bits (80), Expect = 0.055,   Method: Compositional matrix adjust.
 Identities = 22/70 (31%), Positives = 33/70 (47%)
 Frame = +2

Query: 368 GTMDSQIKIWDLKERTNVANFPGHSGPITSIAFSENGYYLATAADDSSVKLWDLRKLKNF 427
           G  DS  + + L      A   GH GPI S+AF  +G   A+  +D  V      ++K+F
Sbjct: 275 GKFDS--RFFHLIYEEEFARLKGHFGPINSLAFHPDGKSYASGGEDGFV------RVKSF 430

Query: 428 KTLQLDNNFE 437
            +   +N FE
Sbjct: 431 DSTYFENIFE 460

 Score = 33.5 bits (75), Expect = 0.22,   Method: Compositional matrix adjust.
 Identities = 15/43 (34%), Positives = 22/43 (51%)
 Frame = +2

Query: 254 EQILATLKGHTKKVTSVVFHPSQELVFSASPDATIRIWSVPNT 296
           E+  A LKGH   + S+ FHP  +   S   D  +R+ S  +T
Sbjct: 311 EEEFARLKGHFGPINSLAFHPDGKSYASGGEDGFVRVKSFDST 439
>30295
          Length = 593

 Score = 35.0 bits (79), Expect = 0.067,   Method: Compositional matrix adjust.
 Identities = 29/122 (23%), Positives = 52/122 (42%), Gaps = 2/122 (1%)
 Frame = +2

Query: 259 TLKGHTKKVTSVVFHPSQELVFSASPDATIRIWSVPNTSCVQVVRAHESAVTGLSLHATG 318
           TL+ H  K+ ++ +      + SAS D  + +W    T+ V  +    S V   +   +G
Sbjct: 230 TLRXHLAKIYAMHWATDSRNLVSASQDGKLIVWDGYTTNKVHAIPLRSSWVMTCAYAPSG 409

Query: 319 DYLLSSSDDQYWAFSDIQTGRVLTKVTDETSGCS--LTCAQFHPDGLIFGTGTMDSQIKI 376
            Y+     D   +   ++T     +V+ E  G +  L+C +F  D  I  T + D    +
Sbjct: 410 GYVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFIDDNQIV-TSSGDMTCAL 586

Query: 377 WD 378
           WD
Sbjct: 587 WD 592
>01598
          Length = 1545

 Score = 35.0 bits (79), Expect = 0.068,   Method: Compositional matrix adjust.
 Identities = 19/62 (30%), Positives = 33/62 (53%), Gaps = 1/62 (1%)
 Frame = +1

Query: 359  HPDGLIFGTGTMDSQIKIWDLKERTNVANFPGHSGPITSIAFSE-NGYYLATAADDSSVK 417
            H D  +   G  D++  +WD+++ T +A F GH G + +  FS  +   + T   D+SV 
Sbjct: 1333 HHDARLVSVG-YDAEAFVWDVQKGTALAQFKGHMGRLLTCQFSGLDPDLVMTGGSDASVH 1509

Query: 418  LW 419
            +W
Sbjct: 1510 VW 1515

 Score = 28.1 bits (61), Expect = 9.8,   Method: Compositional matrix adjust.
 Identities = 17/68 (25%), Positives = 29/68 (42%), Gaps = 1/68 (1%)
 Frame = +1

Query: 360 PDGLIFGTGTMDSQIKIWDLKERTNVANFPGHSGPITSIAFSE-NGYYLATAADDSSVKL 418
           PD     T   D Q+ +WDL+    VA+     G +  +  S  +   +A    DS ++ 
Sbjct: 409 PDSKTLCTFAQDRQVVLWDLETMEAVASMATLGGHVYCVRTSPIDPGRVAVGVGDSMIRT 588

Query: 419 WDLRKLKN 426
           W++    N
Sbjct: 589 WNMSNKTN 612
>02948
          Length = 1207

 Score = 35.0 bits (79), Expect = 0.070,   Method: Compositional matrix adjust.
 Identities = 19/74 (25%), Positives = 35/74 (47%), Gaps = 3/74 (4%)
 Frame = -2

Query: 352 SLTCAQFHPDGLIFGTGTMDSQIKIW---DLKERTNVANFPGHSGPITSIAFSENGYYLA 408
           + TC   HP  +   TG    +I  W   D +++T ++    HS P+T +AF+  G  L 
Sbjct: 750 AFTCVSCHPTDVCIATGHASGKITFWWNFD-QDKTVLSVSHWHSLPVTCLAFTPEGSCLL 574

Query: 409 TAADDSSVKLWDLR 422
           +   + ++  W + 
Sbjct: 573 SGGHECTLVRWQMN 532
>21960
          Length = 756

 Score = 35.0 bits (79), Expect = 0.074,   Method: Compositional matrix adjust.
 Identities = 33/149 (22%), Positives = 63/149 (42%), Gaps = 12/149 (8%)
 Frame = +1

Query: 241 GADKNVVVFDK----STEQILATLKGHTKKVTSVVFHPSQELVFSASPDATIRIWSVPNT 296
           G+D  + V+DK     T   ++       ++T  V++ S   + ++  DA I +   P  
Sbjct: 139 GSDDKLRVYDKRKLDKTVHEMSPKDTKVSQITCAVYNHSGSEILASYSDAAIYLL*QPQL 318

Query: 297 SCVQVV----RAHE----SAVTGLSLHATGDYLLSSSDDQYWAFSDIQTGRVLTKVTDET 348
              ++     R H+      V     H+  ++++S SDD    + D  T  V   +  + 
Sbjct: 319 QGRRISALLRRPHK*PYHQRVNFFGPHS--EHIISGSDDGNIFYWDKNTEAVTNFMKGDD 492

Query: 349 SGCSLTCAQFHPDGLIFGTGTMDSQIKIW 377
           +G  + C + HP   +  T  +D  +KIW
Sbjct: 493 AGV-VNCLEQHPTMPVLATSGLDHNVKIW 576
>36111
          Length = 687

 Score = 35.0 bits (79), Expect = 0.076,   Method: Compositional matrix adjust.
 Identities = 19/59 (32%), Positives = 27/59 (45%)
 Frame = +2

Query: 353 LTCAQFHPDGLIFGTGTMDSQIKIWDLKERTNVANFPGHSGPITSIAFSENGYYLATAA 411
           +    FH     F TG  D  + IWD   +  +  F  +   I S+AFS +G  LA A+
Sbjct: 239 VNAVAFHNVYNTFATGGSDGYVNIWDGFHKKRLCXFHRYPTSIASLAFSHDGNVLAIAS 415
>15972
          Length = 1069

 Score = 34.3 bits (77), Expect = 0.13,   Method: Compositional matrix adjust.
 Identities = 16/50 (32%), Positives = 24/50 (48%)
 Frame = +3

Query: 259 TLKGHTKKVTSVVFHPSQELVFSASPDATIRIWSVPNTSCVQVVRAHESA 308
           T  GH   V  +  HPS +L  + S D T+R+W+  N     +    E+A
Sbjct: 222 TFSGHKGPVRHLAVHPSGKLTLTVSQDRTLRLWNNMNGRIAFISNMKEAA 371

 Score = 32.0 bits (71), Expect = 0.57,   Method: Compositional matrix adjust.
 Identities = 14/40 (35%), Positives = 22/40 (55%)
 Frame = +3

Query: 381 ERTNVANFPGHSGPITSIAFSENGYYLATAADDSSVKLWD 420
           ERT    F GH GP+  +A   +G    T + D +++LW+
Sbjct: 216 ERT----FSGHKGPVRHLAVHPSGKLTLTVSQDRTLRLWN 323
>11915
          Length = 737

 Score = 34.3 bits (77), Expect = 0.13,   Method: Compositional matrix adjust.
 Identities = 16/60 (26%), Positives = 31/60 (51%), Gaps = 1/60 (1%)
 Frame = +1

Query: 363 LIFGTGTMDSQIKIWDLKERTNVANFPGHSGPITSIAFS-ENGYYLATAADDSSVKLWDL 421
           L+  TG +  +IK+W+ +    +     H   +  + F+ +N   L +A+ D +VKLW+ 
Sbjct: 445 LVLATGHVSGRIKLWNCETGKLLIEMMDHKATVHDLHFAADNSLCLMSASHDGTVKLWEF 624
>31474
          Length = 403

 Score = 33.9 bits (76), Expect = 0.18,   Method: Composition-based stats.
 Identities = 23/78 (29%), Positives = 40/78 (51%), Gaps = 5/78 (6%)
 Frame = -3

Query: 241 GADKNVVVFDKSTEQIL--ATLK-GHTKKVTSVVFHPSQELVFSASPDATIRIWSVPNT- 296
           G+DK + ++ K  +  +  +TL   HT+ V S+ + P    + SAS DAT  +WS     
Sbjct: 248 GSDKIIKIWGKEGDNWVCKSTLTDAHTRTVRSLGWSPCGNYLSSASFDATTAVWSRKGGE 69

Query: 297 -SCVQVVRAHESAVTGLS 313
             C+  +  HE+ V  ++
Sbjct: 68  FECIATLEGHENEVKAVA 15
>15337
          Length = 860

 Score = 33.9 bits (76), Expect = 0.18,   Method: Compositional matrix adjust.
 Identities = 18/67 (26%), Positives = 26/67 (38%)
 Frame = -1

Query: 352 SLTCAQFHPDGLIFGTGTMDSQIKIWDLKERTNVANFPGHSGPITSIAFSENGYYLATAA 411
            L C  + PDG    TG  D  + +W   E+  V    GH   +  +AF     +   A 
Sbjct: 197 GLLCVCWSPDGKYIVTGGEDDLVTVWSFHEKRVVCRGHGHKSWVNVVAFD---IHTCLAC 27

Query: 412 DDSSVKL 418
           DD   + 
Sbjct: 26  DDEDCEF 6

 Score = 33.1 bits (74), Expect = 0.27,   Method: Compositional matrix adjust.
 Identities = 15/70 (21%), Positives = 33/70 (47%)
 Frame = -1

Query: 241 GADKNVVVFDKSTEQILATLKGHTKKVTSVVFHPSQELVFSASPDATIRIWSVPNTSCVQ 300
           G D ++ VF+ ++ +++ T+K +   +  V + P  + + +   D  + +WS      V 
Sbjct: 272 GQDGHLRVFNYNSMELIGTMKSYFGGLLCVCWSPDGKYIVTGGEDDLVTVWSFHEKRVVC 93

Query: 301 VVRAHESAVT 310
               H+S V 
Sbjct: 92  RGHGHKSWVN 63

 Score = 30.8 bits (68), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 31/140 (22%), Positives = 56/140 (40%), Gaps = 15/140 (10%)
 Frame = -1

Query: 353 LTCAQFHPDGLIFGTGTMDSQIKIWDLKERTNVANFPGHSGPITSIAFSENGYYLATAAD 412
           L C Q  P+   F  G   S         R  +  +   +G I+  AFS    YLA    
Sbjct: 446 LPCGQTPPNYQPFKQGEGYSVFTCKTKSTRNPLYRWVVGTGAISEFAFSPCSRYLAVVGQ 267

Query: 413 DSSVKLWDLRKLKNFKTLQLDNNF-EVKSLIFDQSGTYLALGGTD--VQIY-------IC 462
           D  +++++   ++   T++  + F  +  + +   G Y+  GG D  V ++       +C
Sbjct: 266 DGHLRVFNYNSMELIGTMK--SYFGGLLCVCWSPDGKYIVTGGEDDLVTVWSFHEKRVVC 93

Query: 463 -----KQWTEILHFTEHSGL 477
                K W  ++ F  H+ L
Sbjct: 92  RGHGHKSWVNVVAFDIHTCL 33
>01805
          Length = 2124

 Score = 32.7 bits (73), Expect = 0.32,   Method: Compositional matrix adjust.
 Identities = 39/186 (20%), Positives = 76/186 (40%), Gaps = 3/186 (1%)
 Frame = -1

Query: 259 TLKGHTKKVTSVVFH-PSQELVFSASPDATIRIWSVPNTSCVQVVRAHESAVTGLSLHAT 317
           ++ GHT+ V  + ++  ++ ++ SAS D T+ +W +           H   V   + H  
Sbjct: 591 SVTGHTQAVLDLSWNRNARHVLASASADTTVALWDLSEGKMAMNFTQHSREVQCCNWHPQ 412

Query: 318 GDY-LLSSSDDQYWAFSDIQTGRVLTKVTDETSGCSLTCAQFHPDGLIFGTGTMDSQIKI 376
            +  LL+ S D      D ++     K +    G        H + L     T    +  
Sbjct: 411 EEQTLLTGSFDNTVKVVDCRSAETCHK-SWTVEGEVEKAVWNHHNPLQLLACTDKGMVYC 235

Query: 377 WDLKERTNVANFPGHSGPITSIAFSEN-GYYLATAADDSSVKLWDLRKLKNFKTLQLDNN 435
           +D++    V +   HS  +T +  S      + T ++D ++K+WD++  K   T     N
Sbjct: 234 FDIRHEKPVFSVGAHSSCVTGVCLSSQIPGLMITTSEDKTMKVWDIQDDK--PTHVFSRN 61

Query: 436 FEVKSL 441
            ++K L
Sbjct: 60  LKMKEL 43
>09883
          Length = 650

 Score = 32.3 bits (72), Expect = 0.41,   Method: Compositional matrix adjust.
 Identities = 33/115 (28%), Positives = 49/115 (42%), Gaps = 6/115 (5%)
 Frame = +3

Query: 392 SGPITS-----IAFSENGYYLATAADDSSVKLWDLRKLKNFKTLQLDNNFEVKSLIFDQS 446
           SGP+T      IA S +G  +A  +  SSV  WD    +   TL   +   + +L FD S
Sbjct: 24  SGPVTLEGASLIALSPDGRTVAICSQ-SSVVFWDAVACEEMHTLHSLHAEPITALAFDNS 200

Query: 447 GTYLALGGTDVQIYICKQWTEILHFTEHSGLTTGVA-FGHHAKFIASTGMDRSLK 500
             YL   G         +  +++H     G  T +A   H  K  +STGM   ++
Sbjct: 201 NHYLVTCG--------DKHIQVIHNV--PGYKTTIADLLHREKKASSTGMRDRIR 335

 Score = 28.5 bits (62), Expect = 6.0,   Method: Compositional matrix adjust.
 Identities = 16/54 (29%), Positives = 24/54 (44%), Gaps = 1/54 (1%)
 Frame = +3

Query: 360 PDGLIFGTGTMDSQIKIWDLKERTNVANFPG-HSGPITSIAFSENGYYLATAAD 412
           PDG      +  S +  WD      +      H+ PIT++AF  + +YL T  D
Sbjct: 69  PDGRTVAICSQ-SSVVFWDAVACEEMHTLHSLHAEPITALAFDNSNHYLVTCGD 227
>29912
          Length = 510

 Score = 32.0 bits (71), Expect = 0.56,   Method: Compositional matrix adjust.
 Identities = 40/161 (24%), Positives = 68/161 (42%), Gaps = 7/161 (4%)
 Frame = +3

Query: 306 ESAVTGLSLHATGDYL-LSSSDDQYWAFSDIQTGRVLTKVTDETSGCSLTCAQFHPDGLI 364
           E  +  +S    G+YL L +S  +   +   Q  ++ T         SL+   F     I
Sbjct: 9   EEYIGAVSWIKEGNYLALGTSTGEVQVWDVTQQKKLRTMAGHAARVGSLSWNSF-----I 173

Query: 365 FGTGTMDSQIKIWDLK-ERTNVANFPGHSGPITSIAFSENGYYLATAADDSSVKLWDLRK 423
             +G+    I   D++    +V    GHS  +  + +S +G YLA+ A+D+ + +W  + 
Sbjct: 174 VSSGSRSGNIHHHDVRVADHHVGTLSGHSQEVCGLRWSPDGKYLASGANDNLLCVWPAQV 353

Query: 424 LKNFKTLQL----DNNFEVKSLIF-DQSGTYLALGGTDVQI 459
                T  L     +   VK+L +     + LA GG DV I
Sbjct: 354 TGGNSTQPLHTFSQHQAAVKALAWCPWQPSXLASGGGDVLI 476
>03044
          Length = 1952

 Score = 31.6 bits (70), Expect = 0.79,   Method: Compositional matrix adjust.
 Identities = 46/228 (20%), Positives = 87/228 (38%), Gaps = 40/228 (17%)
 Frame = -2

Query: 233  DTNKILTGGADKNVVVFDK--STEQILATLKGHTKKVTSVVFHPSQELVFSASPDATIRI 290
            D N +     D  V ++ K  S  Q   TL  H ++VT + + P    + +   D    +
Sbjct: 1753 DRNGLALSLNDHEVKIYKKNGSKWQETDTLGEHGQRVTGIDWAPKSNRIVTCGADRNAYV 1574

Query: 291  WSVPN---------------TSCVQVVRAHESAVTGLSLHATGDYLLSSS----DDQYWA 331
            W+  +                +CV+          G S       L+S S    + ++W 
Sbjct: 1573 WTYQDGKWQPHLVILRINRAATCVKWSPEENKFAVGSSAR-----LISVSYYEEEHRWW- 1412

Query: 332  FSDIQTGRVLTKVTDETSGCSLTCAQFHPDGLIFGTGTMDSQIKIWD--LKERTN----- 384
                     ++K   +    ++TC  +HP+ ++   G+ D + +++   +KE        
Sbjct: 1411 ---------VSKHIKKPIRSTVTCLDWHPNNILIAAGSTDFKARVFSGYVKETEAKPGPN 1259

Query: 385  -----------VANFP-GHSGPITSIAFSENGYYLATAADDSSVKLWD 420
                       +A F  G  G + +++FS +G  +A  A DSSV + D
Sbjct: 1258 SWGSKMTFAALMAEFSNGGGGWVHAVSFSPSGEKIAWVAHDSSVSVGD 1115

 Score = 29.6 bits (65), Expect = 3.3,   Method: Compositional matrix adjust.
 Identities = 17/62 (27%), Positives = 30/62 (48%), Gaps = 2/62 (3%)
 Frame = -2

Query: 444  DQSGTYLALGGTDVQIYI--CKQWTEILHFTEHSGLTTGVAFGHHAKFIASTGMDRSLKF 501
            D++G  L+L   +V+IY     +W E     EH    TG+ +   +  I + G DR+   
Sbjct: 1753 DRNGLALSLNDHEVKIYKKNGSKWQETDTLGEHGQRVTGIDWAPKSNRIVTCGADRNAYV 1574

Query: 502  YS 503
            ++
Sbjct: 1573 WT 1568
>00499
          Length = 4026

 Score = 31.6 bits (70), Expect = 0.81,   Method: Compositional matrix adjust.
 Identities = 18/64 (28%), Positives = 33/64 (51%)
 Frame = -3

Query: 335  IQTGRVLTKVTDETSGCSLTCAQFHPDGLIFGTGTMDSQIKIWDLKERTNVANFPGHSGP 394
            +Q GRV+  VT  +   +L+    H D L+ G GT +  +++   K+  ++    GH   
Sbjct: 1177 LQGGRVVDAVTGHSHDLALSLTALHDDQLLLGGGTREHDLRVV-AKDLVDLGR--GHVTQ 1007

Query: 395  ITSI 398
            +TS+
Sbjct: 1006 VTSV 995
>25400
          Length = 462

 Score = 31.2 bits (69), Expect = 0.94,   Method: Composition-based stats.
 Identities = 16/56 (28%), Positives = 29/56 (51%), Gaps = 1/56 (1%)
 Frame = +3

Query: 237 ILTGGADKNVVVFDKSTEQILATLKG-HTKKVTSVVFHPSQELVFSASPDATIRIW 291
           + +G A   ++++D  T +++  L G H   V  V +HP    + S+S D T+  W
Sbjct: 6   VYSGCATGTILIYDLLTGRVVRKLDGGHRSCVRDVSWHPYTNTLISSSWDGTVGKW 173
>04955
          Length = 1295

 Score = 30.4 bits (67), Expect = 1.9,   Method: Compositional matrix adjust.
 Identities = 16/54 (29%), Positives = 29/54 (53%), Gaps = 3/54 (5%)
 Frame = +2

Query: 3   LICSISNEVPEHPCVSPV---SNHVYERRLIEKYIAENGTDPINNQPLSEEQLI 53
            +C+++N+V  +   + V   S  V     +EK I ++  DP NN+ L E+ +I
Sbjct: 203 FVCAVTNDVLGNSVPAAVLRTSGTVVTMECVEKIIKKDMVDPTNNKKLREKDII 364
>34511
          Length = 1037

 Score = 30.0 bits (66), Expect = 2.0,   Method: Compositional matrix adjust.
 Identities = 12/40 (30%), Positives = 24/40 (60%)
 Frame = +3

Query: 381 ERTNVANFPGHSGPITSIAFSENGYYLATAADDSSVKLWD 420
           ER+ +    GH   ++ +  +ENG  +AT + DS +++W+
Sbjct: 45  ERSGI--LAGHDNRVSCLGVTENGMSVATGSWDSFLRVWN 158
>20271
          Length = 567

 Score = 30.0 bits (66), Expect = 2.3,   Method: Compositional matrix adjust.
 Identities = 16/55 (29%), Positives = 33/55 (60%), Gaps = 6/55 (10%)
 Frame = -1

Query: 388 FPGHSGPITSI----AFSENGY--YLATAADDSSVKLWDLRKLKNFKTLQLDNNF 436
           + GH GPIT+I    A  +  +  +  TA+ D +VKLW++++ K   + + ++++
Sbjct: 297 YEGHQGPITAIDTHHAAGQIDFSPFFLTASFDWTVKLWNIKEQKYVCSFEDNSDY 133
>30176
          Length = 365

 Score = 30.0 bits (66), Expect = 2.5,   Method: Compositional matrix adjust.
 Identities = 14/33 (42%), Positives = 19/33 (57%)
 Frame = +2

Query: 259 TLKGHTKKVTSVVFHPSQELVFSASPDATIRIW 291
           TLK HT  V ++ F  +   + S S D TI+IW
Sbjct: 5   TLKSHTSTVWNLTFDKTGTRLASCSDDKTIKIW 103

 Score = 28.5 bits (62), Expect = 5.9,   Method: Compositional matrix adjust.
 Identities = 9/29 (31%), Positives = 19/29 (65%)
 Frame = +2

Query: 391 HSGPITSIAFSENGYYLATAADDSSVKLW 419
           H+  + ++ F + G  LA+ +DD ++K+W
Sbjct: 17  HTSTVWNLTFDKTGTRLASCSDDKTIKIW 103
>27681
          Length = 465

 Score = 29.6 bits (65), Expect = 3.1,   Method: Composition-based stats.
 Identities = 22/80 (27%), Positives = 37/80 (46%), Gaps = 15/80 (18%)
 Frame = +2

Query: 355 CAQFHPDGLIFGTGTMDSQIKIWDLKERT-NVAN--------------FPGHSGPITSIA 399
           CA ++P   +  +G+ DS  +IW++   T N AN               P +   +TS+ 
Sbjct: 11  CA-WNPTNDLLASGSGDSTARIWNMTSETPNNANQLVLRHCIQKGGTEVPSNKD-VTSLD 184

Query: 400 FSENGYYLATAADDSSVKLW 419
           ++  G  LAT + D   +LW
Sbjct: 185 WNSEGTLLATGSYDGYARLW 244
>20036
          Length = 1849

 Score = 28.9 bits (63), Expect = 4.5,   Method: Compositional matrix adjust.
 Identities = 20/65 (30%), Positives = 32/65 (49%), Gaps = 1/65 (1%)
 Frame = +3

Query: 224  ILALDLCPSDTNKIL-TGGADKNVVVFDKSTEQILATLKGHTKKVTSVVFHPSQELVFSA 282
            +LA   C +D  ++L   GAD N   FD ST  + A   GHT  V  ++  P  +   + 
Sbjct: 1116 MLATSQCRTDMVELLLETGADCNQQDFDGSTALMCACEHGHTAIVQLLLAQPHCDATLTD 1295

Query: 283  SPDAT 287
            + ++T
Sbjct: 1296 NENST 1310
>04524
          Length = 1340

 Score = 28.5 bits (62), Expect = 6.9,   Method: Compositional matrix adjust.
 Identities = 20/59 (33%), Positives = 28/59 (47%), Gaps = 3/59 (5%)
 Frame = -1

Query: 262 GHTKKVTSVVFHPSQELVFSASPDATIRIWSVPNTSCVQVVRAHE---SAVTGLSLHAT 317
           GHT+ V  +V+     ++ S S D T+R W++       V  A E   SAVT     AT
Sbjct: 905 GHTQFVNCLVYVEEFRVLISGSGDCTVRAWNMEGKQLCLVHCAKEQTXSAVTAQQSTAT 729
>13509
          Length = 572

 Score = 28.5 bits (62), Expect = 7.0,   Method: Compositional matrix adjust.
 Identities = 16/54 (29%), Positives = 21/54 (38%)
 Frame = +2

Query: 358 FHPDGLIFGTGTMDSQIKIWDLKERTNVANFPGHSGPITSIAFSENGYYLATAA 411
           FHP      T   D +   WD   RT +        PIT+  F+  G   A A+
Sbjct: 383 FHPVHGTLSTVGSDGRFSFWDKDARTKLKTSEQFDQPITTCNFNAQGNIFAYAS 544
>17298
          Length = 476

 Score = 28.1 bits (61), Expect = 9.0,   Method: Composition-based stats.
 Identities = 13/62 (20%), Positives = 27/62 (43%)
 Frame = -1

Query: 361 DGLIFGTGTMDSQIKIWDLKERTNVANFPGHSGPITSIAFSENGYYLATAADDSSVKLWD 420
           DG++ G      Q           +  +  H+G +  + F+E    + + + D++V+ WD
Sbjct: 275 DGVVVGNNVASGQA----------LRKYRDHAGTVNCVKFNEESTVILSGSLDNTVRAWD 126

Query: 421 LR 422
            R
Sbjct: 125 TR 120
>25522
          Length = 437

 Score = 28.1 bits (61), Expect = 9.7,   Method: Composition-based stats.
 Identities = 13/40 (32%), Positives = 19/40 (47%)
 Frame = -2

Query: 329 YWAFSDIQTGRVLTKVTDETSGCSLTCAQFHPDGLIFGTG 368
           Y    D +T + + K+T   SGC +    F  + L  GTG
Sbjct: 427 YTILLDARTLQTIKKITSRYSGCGIRATSFEGNLLTVGTG 308
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|20544147|ref|NP_082150.1| casein kinase 1, delta
isoform 2 [Mus musculus]
         (409 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

18481                                                                 172   3e-43
16959                                                                 149   2e-36
32357                                                                 103   1e-22
00300                                                                  65   7e-11
06405                                                                  61   7e-10
01718                                                                  54   1e-07
11404                                                                  52   5e-07
01106                                                                  50   1e-06
01756                                                                  50   1e-06
00715                                                                  49   4e-06
16708                                                                  49   4e-06
13592                                                                  48   7e-06
14477                                                                  47   2e-05
29581                                                                  46   2e-05
21079                                                                  45   5e-05
04591                                                                  45   7e-05
14126                                                                  44   1e-04
21433                                                                  44   1e-04
01060                                                                  44   1e-04
11780                                                                  44   1e-04
26711                                                                  44   2e-04
30755                                                                  43   2e-04
03240                                                                  42   4e-04
21808                                                                  42   4e-04
01392                                                                  42   7e-04
18921                                                                  41   8e-04
28638                                                                  41   0.001
27546                                                                  41   0.001
15910                                                                  40   0.002
14420                                                                  40   0.002
01966                                                                  40   0.002
26009                                                                  40   0.002
21800                                                                  40   0.002
31885                                                                  38   0.006
26560                                                                  38   0.006
17975                                                                  38   0.007
19301                                                                  38   0.007
27405                                                                  37   0.010
18484                                                                  37   0.010
12786                                                                  37   0.011
01707                                                                  37   0.014
12721                                                                  37   0.021
36481                                                                  36   0.028
31489                                                                  36   0.032
04138                                                                  35   0.039
09277                                                                  35   0.049
03508                                                                  34   0.087
07940                                                                  33   0.15 
28157                                                                  33   0.16 
13212                                                                  32   0.36 
13066                                                                  32   0.52 
19094                                                                  32   0.62 
29360                                                                  31   1.1  
19761                                                                  30   1.4  
37602                                                                  30   2.5  
32359                                                                  28   7.6  
>18481
          Length = 437

 Score =  172 bits (435), Expect = 3e-43,   Method: Compositional matrix adjust.
 Identities = 76/145 (52%), Positives = 110/145 (75%)
 Frame = -1

Query: 23  IYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQGGVGIPTIRWCGAEGDYNVMVM 82
           IY G +   G+++A+K+E +  KH  LH E+K+Y+ +    G+PT+   G E  +N +VM
Sbjct: 437 IYQGYNTQDGKDIAVKIEAIDVKHQLLHYEAKVYEQIGRHPGLPTMYHYGTEKHFNALVM 258

Query: 83  ELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMGLGKKG 142
           ELLGPSLE+LF  C R+F+LKT+L+++DQ++SR+E+IH K FIHRD+KPDNFLMGLG+  
Sbjct: 257 ELLGPSLEELFVICKRRFTLKTILMVSDQLLSRLEFIHQKCFIHRDLKPDNFLMGLGRHC 78

Query: 143 NLVYIIDFGLAKKYRDARTHQHIPY 167
           + +YIIDFGL+K+Y+D +   HIPY
Sbjct: 77  HRLYIIDFGLSKRYKDTQGTMHIPY 3
>16959
          Length = 1747

 Score =  149 bits (377), Expect = 2e-36,   Method: Compositional matrix adjust.
 Identities = 67/97 (69%), Positives = 81/97 (83%)
 Frame = -1

Query: 197  ESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVLCKGYPSEFATYLNFCR 256
            E+LGYVLMYFN GSLPWQGLKAATK+QK ERISEKK++TP++ LCK +PSEF+ +LN+ R
Sbjct: 1747 EALGYVLMYFNRGSLPWQGLKAATKKQKCERISEKKIATPVDSLCKSFPSEFSIFLNYSR 1568

Query: 257  SLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNML 293
             LRFD+ PDY+YLRQLFR LF      +DY FDWN+L
Sbjct: 1567 DLRFDEGPDYTYLRQLFRVLFRTYNHHFDYAFDWNIL 1457
>32357
          Length = 625

 Score =  103 bits (257), Expect = 1e-22,   Method: Compositional matrix adjust.
 Identities = 68/159 (42%), Positives = 91/159 (57%), Gaps = 6/159 (3%)
 Frame = -2

Query: 2   ELRVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQG 61
           +L V  +YRL +KIGSGSFG+IYLG    +GEEVA+KLE    KHPQL+ ESK+Y+++QG
Sbjct: 453 DLLVNGKYRLMKKIGSGSFGEIYLGVHNTSGEEVAVKLELKNAKHPQLYYESKLYRVLQG 274

Query: 62  GVGIPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLA-----DQMISRI 116
           GVGIP  RW G E       M       + ++  CS      +    A     D   + I
Sbjct: 273 GVGIPYCRWFGQEST----TM*W*WIYWDPVWKTCSTTVGANSP*NSAHARRPDDQQAGI 106

Query: 117 EYIHSKNFIHRDV-KPDNFLMGLGKKGNLVYIIDFGLAK 154
             IH+K  +H    +    LMG+G+  N V+IID+GLAK
Sbjct: 105 --IHNK--LHSSGPQARQLLMGIGRHANKVFIIDYGLAK 1
>00300
          Length = 2318

 Score = 64.7 bits (156), Expect = 7e-11,   Method: Compositional matrix adjust.
 Identities = 62/225 (27%), Positives = 103/225 (45%), Gaps = 12/225 (5%)
 Frame = -1

Query: 4    RVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIK-LECVKTKHPQLHIESKIYKMMQGG 62
            RV  R++ G KIG G FG +Y   +++ GE +A+K ++       QL       K+ +G 
Sbjct: 1667 RVNFRWQRGNKIGEGQFGKVYTAVNMSTGELMALKEMKFQPNDLQQLREMCDEIKIFEGI 1488

Query: 63   VGIPTIRWCGAE--GDYNVMVMELLGP-SLED-----LFNFCSRKFSLKTVLLLADQMIS 114
                 +++ G E   D  +M ME     ++E+     L  +  R+++ + VL        
Sbjct: 1487 QHENLVKYYGVEVHKDEMLMFMEYCDTGTIEEAAKMGLPEYLIRRYTREIVLA------- 1329

Query: 115  RIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLT 174
             + ++H  + +HRD+K  N    L   G+ V + DFG + K    ++H  +P  E  NL 
Sbjct: 1328 -VNHLHENSIVHRDIKGANIF--LTSNGH-VKLGDFGCSVKL---KSHTTMP-GEFHNLV 1173

Query: 175  GTARYASINTHLGIEQ---SRRDDLESLGYVLMYFNLGSLPWQGL 216
            GT  Y +       +Q    R  D+ SLG V++    G  PW  L
Sbjct: 1172 GTTAYMAPEVFTQNDQGGYGRAADIWSLGCVVIEMATGKRPWHDL 1038
>06405
          Length = 1965

 Score = 61.2 bits (147), Expect = 7e-10,   Method: Compositional matrix adjust.
 Identities = 67/277 (24%), Positives = 116/277 (41%), Gaps = 5/277 (1%)
 Frame = +1

Query: 11  LGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHI---ESKIYKMMQGGVGIPT 67
           +  ++G G +GD+Y        + VA+K   +K     L+    E+ I K M+    +  
Sbjct: 271 MKHRLGGGQYGDVYEAMWKRYNKIVAVK--TLKEDTMALNDFLEEAAIMKEMKHPNLVQL 444

Query: 68  IRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLL-LADQMISRIEYIHSKNFIH 126
           +  C  E  + ++   +   +L D     +R+ +  T L+ +A Q+ S + Y+ +KNFIH
Sbjct: 445 LGVCTREPPFYIVTEFMPHGNLLDYLRSSTREENGPTALMYMATQIASGMAYLETKNFIH 624

Query: 127 RDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASINTHL 186
           RD+   N L+      N+V + DFGLA+  +D     HI  +     T     A  N   
Sbjct: 625 RDLAARNCLVA---DSNMVKVADFGLARLMKDDTYTAHIGAKFPIKWTAPEGLA-FNRF- 789

Query: 187 GIEQSRRDDLESLGYVLMYF-NLGSLPWQGLKAATKRQKYERISEKKMSTPIEVLCKGYP 245
               S R D+ + G +L      G  P+ G++        ER    +M  P      G P
Sbjct: 790 ----STRSDIWAFGVLLWELATYGMSPYPGVELTEVYHLLER--GYRMERP-----PGTP 936

Query: 246 SEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGF 282
           ++    +  C      D+P +  +  L  N+F +   
Sbjct: 937 ADVYILMLKCWQWDPKDRPTFKEIHFLLENMFEKSSI 1047
>01718
          Length = 959

 Score = 54.3 bits (129), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 45/194 (23%), Positives = 83/194 (42%), Gaps = 1/194 (0%)
 Frame = +3

Query: 11  LGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQGGVGIPTIRW 70
           +  KIG+G F +++  T    G+ +A+K+  + +    +  E ++   +Q    +  +  
Sbjct: 159 ICEKIGAGFFSEVFKVTHRITGQVMALKMNTMTSNRHNMLREVQLLNRLQHANILRFMGV 338

Query: 71  CGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVK 130
           C  EG  + +   +   +LE L      +      + L   +   ++Y+HS  FIHRD+ 
Sbjct: 339 CVHEGQLHALTEYIPSGNLEQLLEKKDEELPWTQRIQLTLGLARGLDYLHSTRFIHRDLT 518

Query: 131 PDNFLMGL-GKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASINTHLGIE 189
             N L+      G    I DFGLA K  D    + +P        G+  + +     G  
Sbjct: 519 SKNILIRREDNHGYHAVIADFGLATKIPDPLDKEKLPT------VGSPYWMAPEVLNGHF 680

Query: 190 QSRRDDLESLGYVL 203
            + R DL S+G ++
Sbjct: 681 YNERADLFSVGIIM 722
>11404
          Length = 563

 Score = 51.6 bits (122), Expect = 5e-07,   Method: Compositional matrix adjust.
 Identities = 44/142 (30%), Positives = 67/142 (47%), Gaps = 11/142 (7%)
 Frame = +1

Query: 6   GNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHP---QLHIESKIYKMMQ-- 60
            +RY +   IG GSFG +    D    E+VAIK+  +K K P   Q  IE K+ +MM   
Sbjct: 136 ADRYEIDSLIGKGSFGQVVKAYDHTDNEQVAIKI--IKNKKPFLNQAQIEVKLLEMMNRH 309

Query: 61  ---GGVGIPTIRWCGAEGDYNVMVMELLGPSLEDLF-NFCSRKFSLKTVLLLADQMISRI 116
                  I  ++       +  +V ELL  +L DL  N   R  SL      A Q+ + +
Sbjct: 310 DTDNKYYIVRLKRHFMFRSHLCLVFELLSYNLYDLLRNTNFRGVSLNLTRKFAQQLCTAL 489

Query: 117 EYIHS--KNFIHRDVKPDNFLM 136
            ++ +   + IH D+KP+N L+
Sbjct: 490 LFLATPEMSIIHCDLKPENILL 555
>01106
          Length = 878

 Score = 50.4 bits (119), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 43/151 (28%), Positives = 71/151 (47%), Gaps = 20/151 (13%)
 Frame = +3

Query: 8   RYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIES-----KIYKMM-QG 61
           RY + RK+G G F  ++L  D+     VA+K+     K  Q + E+     K+ K + + 
Sbjct: 321 RYHVIRKLGWGHFSTVWLCWDLTCKRFVALKV----VKSAQHYTETALDEVKLLKCVRES 488

Query: 62  GVGIPTIRWC----------GAEGDYNVMVMELLGPSLEDLF---NFCSRKFSLKTVLLL 108
            V  P    C          G  G +  MV E+LG +L  L    N+  +   +  V L+
Sbjct: 489 DVADPARAKCVQLLDDFKISGVNGTHVAMVFEVLGYNLLKLIIRSNY--QGIPIHNVKLI 662

Query: 109 ADQMISRIEYIHSK-NFIHRDVKPDNFLMGL 138
             Q++  + Y+H+K   IH D+KP+N L+ +
Sbjct: 663 IRQVLEGLSYMHAKCRIIHTDIKPENILICV 755
>01756
          Length = 1858

 Score = 50.4 bits (119), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 41/160 (25%), Positives = 71/160 (44%), Gaps = 11/160 (6%)
 Frame = -3

Query: 8    RYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHI----ESKIYKMMQGGV 63
            +Y    KIG G+FG+++        + VA+K   +  +     I    E KI +++    
Sbjct: 1739 KYEKLAKIGQGTFGEVFKARCKKTKQVVAMKKVLMDNEKEGFPITALREIKILQLLNHEN 1560

Query: 64   GIPTIRWCGAEGD----YNVM---VMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRI 116
             +  I  C  +      Y  M   V E     L  L +  S  F+L  +  +  Q+++ +
Sbjct: 1559 VVDLIEICSTKATSANRYKSMFYLVFEFCEHDLAGLLSNMSVVFNLPEIKEVMKQLMNGL 1380

Query: 117  EYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKY 156
             YIH    +HRD+K  N L+    K  ++ + DFGLA+ +
Sbjct: 1379 YYIHRNKILHRDMKAANILI---TKQGVLKLADFGLARAF 1269
>00715
          Length = 1788

 Score = 48.9 bits (115), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 56/227 (24%), Positives = 88/227 (38%), Gaps = 19/227 (8%)
 Frame = +1

Query: 80  MVMELLGP-SLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMGL 138
           + ME +GP +L+ + N   +       L LA QM   + Y+HS N +H D+KP N L+  
Sbjct: 166 LAMEYVGPLNLQTILNDHQQDIDSSMRLSLALQMARGLHYLHSINIVHLDLKPANCLLTR 345

Query: 139 GKKGNLVYIIDFGLAKKYRDARTHQHIPYRE-----------------NKNLTGTARYAS 181
             K   + I DFG   +     T   +  RE                    L GT  Y +
Sbjct: 346 DLK---LRIADFGCCHQL--TPTGLDMGEREGGMAGNELELTPVQGAWKNELAGTLAYRA 510

Query: 182 INTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEK-KMSTPIEVL 240
                G++ S R D+ SLG  L        P++G+ A      Y+ +S+  +   P    
Sbjct: 511 PELLKGLQPSVRSDVYSLGITLWQMCTRQGPYEGVPAHAV--VYQVVSKDLRPCPPPSTE 684

Query: 241 CKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYV 287
              +   F      C + R +D+P          ++ H  G   DY+
Sbjct: 685 DDPFEVMFRDLYTQCWARRVEDRPTS-------LDVVHAIGLWLDYM 804
>16708
          Length = 1397

 Score = 48.5 bits (114), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 64/256 (25%), Positives = 105/256 (41%), Gaps = 24/256 (9%)
 Frame = -1

Query: 15   IGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQGGVGIPTI--RW-- 70
            +G G FG +Y    ++  E+ A+K   +   H    +E+     ++GG  +  +   W  
Sbjct: 1379 LGKGVFGKVYEARLLSTHEKAALKTS-ILCHHSLDEVEA--LGRIEGGFYLAQMFGAWVT 1209

Query: 71   CGAEGDYNVMV-MELLGPSLEDLFNFCSRKFSLK-----TVLLLADQMISRIEYIHSKNF 124
            C      N+++    +GP      ++ +++  ++      V  +A Q +  +E+IH    
Sbjct: 1208 CLPFPKMNILLHFYEMGPLCNVYAHYKNKEMPIRWSNPAMVCCIAGQXVCALEHIHELGV 1029

Query: 125  IHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYR--DARTHQHIPYRENKNLTGTARYASI 182
            +H DVK DN L  +   GN   + D+G+A+ Y+   A T  H     NK    T   A++
Sbjct: 1028 VHMDVKADNVL--VDAHGN-CKLTDYGIAQLYKVYPAPTETHSSGCTNKRTFYTRPPATM 858

Query: 183  NTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAA---------TKRQKYERISEKK- 232
                    S R   E  G    YF LG + W    A           K   + R  E + 
Sbjct: 857  TP------SERFSEEGDGIGTDYFRLGQMLWTLTGAVLLHVWVSRPPKLPDWCRTPESEL 696

Query: 233  --MSTPIEVLCKGYPS 246
              MS  IE LC G P+
Sbjct: 695  SGMSDFIEKLCHGDPN 648
>13592
          Length = 980

 Score = 47.8 bits (112), Expect = 7e-06,   Method: Compositional matrix adjust.
 Identities = 55/214 (25%), Positives = 92/214 (42%), Gaps = 14/214 (6%)
 Frame = +2

Query: 14  KIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQ-LHIESKIYKMMQGGVGIPTIRWCG 72
           KIG G FG +Y   +   GE +A+K   ++    + L   ++  K+++G      +R+ G
Sbjct: 5   KIGQGRFGKVYTAVNNNTGELMAMKEIAIQPGETRALKNVAEELKILEGIKHKNLVRYYG 184

Query: 73  AEG--DYNVMVMELLGP-SLEDLFNFC-------SRKFSLKTVLLLADQMISRIEYIHSK 122
            E   +  ++ MEL    +LE L           SR+F+         Q++S +  +H  
Sbjct: 185 IEVHREELLIFMELCSEGTLESLVELTGGLPEALSRRFTA--------QLLSGVAELHKH 340

Query: 123 NFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASI 182
             +HRD+K  N  +  G   N + + DFG A K    + H  +P  E +   GT  Y + 
Sbjct: 341 GIVHRDIKTANIFLVDGS--NSLKLGDFGSAVKI---QAHTTVP-GELQGYVGTQAYMAP 502

Query: 183 NTHLGIE---QSRRDDLESLGYVLMYFNLGSLPW 213
                       R  D+ S+G V++    G  PW
Sbjct: 503 EVFTKTNSDGHGRLADIWSVGCVVVEMASGKRPW 604
>14477
          Length = 493

 Score = 47.0 bits (110), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 40/149 (26%), Positives = 74/149 (49%), Gaps = 8/149 (5%)
 Frame = -1

Query: 14  KIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYK---MMQGGVGIPTIRW 70
           K+G+G+FG +  G       E+ + ++ +K       ++S++ K   +M+    +  +R 
Sbjct: 469 KLGAGNFGSVMKGVCRLDDREIPVAIKVLKNADLDPSVQSELIKEAEVMKKMDHMHIVRL 290

Query: 71  CG-AEGDYNVMVMEL--LGPSLEDLFNFC--SRKFSLKTVLLLADQMISRIEYIHSKNFI 125
            G  EG+  ++V+EL  LGP    L  F   ++   L  +L L  Q+   +EY+ +  F+
Sbjct: 289 IGLCEGETMMLVLELAKLGP----LNKFLPKNKHLPLWNILELMWQVSQGMEYLEANKFV 122

Query: 126 HRDVKPDNFLMGLGKKGNLVYIIDFGLAK 154
           HRD+   N L+      +   I DFG++K
Sbjct: 121 HRDLAARNILLC---DEHFAKISDFGMSK 44
>29581
          Length = 1278

 Score = 46.2 bits (108), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 31/85 (36%), Positives = 40/85 (47%)
 Frame = -2

Query: 72   GAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKP 131
            G   D   +VME     L  L +     FS   V  +  Q++  + Y+H    IHRD+K 
Sbjct: 1142 GKSLDSLFLVMEYCEQDLASLLDNMPAPFSESQVKCIVLQLLKGLRYLHEAFIIHRDLKV 963

Query: 132  DNFLMGLGKKGNLVYIIDFGLAKKY 156
             N LM    KG  V I DFGLA+ Y
Sbjct: 962  SNLLM--TDKG-CVKIADFGLARNY 897
>21079
          Length = 878

 Score = 45.1 bits (105), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 44/155 (28%), Positives = 70/155 (45%), Gaps = 13/155 (8%)
 Frame = +1

Query: 79  VMVMELLGPSLEDLFNFCSRK-FSL--KTVLLLADQMISRIEYIHSKNFIHRDVKPDNFL 135
           V+VME +G    +LF    R  F L  +  +    Q+ S + Y+H+++ +H D+KP+N L
Sbjct: 52  VLVMEFVGAG--ELFERVIRDDFVLTERDCVHFVRQICSGVGYMHTQSILHLDLKPENVL 225

Query: 136 MGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDD 195
             +    N + IIDFGLA+ Y+   + Q         L GT  + +       E +   D
Sbjct: 226 -CVSDNSNQIKIIDFGLARFYKPGDSLQ--------VLFGTPEFIAPEVVNYDEINFTTD 378

Query: 196 LESLGYVLMYFNLGSL----------PWQGLKAAT 220
           + S+G V+ Y  L  L          PW   +  T
Sbjct: 379 MWSIG-VICYILLSGLSPSRVTTMLRPWPTSQVVT 480
>04591
          Length = 1117

 Score = 44.7 bits (104), Expect = 7e-05,   Method: Compositional matrix adjust.
 Identities = 24/77 (31%), Positives = 41/77 (53%)
 Frame = -2

Query: 80  MVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMGLG 139
           ++ E     L  L N    KFSL     L  Q+++ + YIH+K  +HRD+K  N L+   
Sbjct: 966 LIFEYCDYDLAGLLNNLRVKFSLADKKNLMSQLLNGLFYIHTKQILHRDIKAANILL--- 796

Query: 140 KKGNLVYIIDFGLAKKY 156
            +  ++ + DFGL++ +
Sbjct: 795 TRDGVLKLADFGLSRPW 745
>14126
          Length = 1265

 Score = 43.9 bits (102), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 43/155 (27%), Positives = 71/155 (45%), Gaps = 13/155 (8%)
 Frame = +3

Query: 15  IGSGSFGDIYLGTDI-AAGEEVA---IKLECVKTKHPQLHI-ESKIYKMMQGGVGIPTIR 69
           IG+G++G +Y   D+   GE VA   I+L   +   P + I E  + K ++       +R
Sbjct: 213 IGNGAYGTVYKARDLRNQGEFVAMKRIRLNNTEEGMPMMAIREISMLKQLEQYEHPNVVR 392

Query: 70  WCGAE----GDYNV---MVMELLGPSLEDLFNFC-SRKFSLKTVLLLADQMISRIEYIHS 121
                     D  +   +V E +   L      C S       +  L  Q+++ ++++HS
Sbjct: 393 LLDVSHNTITDREIRLNLVFEYIEHDLATYLAKCPSPGLGPDRIKDLMLQLLNGVDFLHS 572

Query: 122 KNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKY 156
              +HRD+KP N L  + K G L  + DFGLA+ Y
Sbjct: 573 NRIVHRDLKPQNLL--ISKDGRL-KLADFGLARIY 668
>21433
          Length = 590

 Score = 43.9 bits (102), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 31/102 (30%), Positives = 43/102 (42%)
 Frame = +2

Query: 111 QMISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYREN 170
           Q+ S +EY H +  IHRD+KP+N L+        + I DFG +          H P    
Sbjct: 191 QLSSALEYCHYRKVIHRDIKPENLLL---GLKGDLKIADFGWS---------VHAPSSRR 334

Query: 171 KNLTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLP 212
             + GT  Y       G       DL SLG +   F +G+ P
Sbjct: 335 TTMCGTLDYLPPEMVEGKTHDENVDLWSLGVLCYEFLVGTPP 460
>01060
          Length = 1800

 Score = 43.9 bits (102), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 44/179 (24%), Positives = 77/179 (43%), Gaps = 10/179 (5%)
 Frame = +1

Query: 13  RKIGSGSFGDIYLGTDIAAGEEVA---IKLECVKTKHPQLHIESKIYKMMQGGVGIPTIR 69
           +KIG G++G +Y     A G ++A   I+L   +   P   I             I  + 
Sbjct: 91  QKIGEGTYGVVYKCRHRATGRKLAMKKIRLRGSEDGVPSSAIREIAMLRELRHTNIVCLE 270

Query: 70  WCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLL--LADQMISRIEYIHSKNFIHR 127
               E +   +V E L   L+   +       L   L+     Q+++ I + H +  +HR
Sbjct: 271 DVIMEDERLFLVFEFLSMDLKMYIDKFPEGVVLDRRLVKSYVFQIVTGIXFCHQRRIVHR 450

Query: 128 DVKPDNFLMGLGKKGNLVYIIDFGLAKKYR---DARTHQHIP--YRENKNLTGTARYAS 181
           D+KP N L+        + I DFG+A+ +     A TH+ +   YR  + L G ++Y++
Sbjct: 451 DLKPQNLLIN---HTGAIKIADFGMARTFALPVRAYTHEVVTLWYRAPEILMGASKYST 618
>11780
          Length = 1713

 Score = 43.5 bits (101), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 43/147 (29%), Positives = 66/147 (44%), Gaps = 3/147 (2%)
 Frame = +3

Query: 11  LGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQGGVGIPTIRW 70
           +G  IG G FGD+Y G  +  G+ VAIK    K +  Q  ++     +M        +R 
Sbjct: 609 IGEAIGKGDFGDVYKG--MYRGQPVAIKQLKDKDRGEQSFLQEA--SVMTSLRHDNLVRL 776

Query: 71  CGAE-GDYNVMVMELLGPS--LEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHR 127
            G   G+   +V E +G    +E L +      + K  +  A    + +EY+ SK  +HR
Sbjct: 777 IGVVLGETIFLVTEFMGKGNLVEYLRSRGRSVITKKDQINFATDTCAAMEYLESKRLVHR 956

Query: 128 DVKPDNFLMGLGKKGNLVYIIDFGLAK 154
           D+   N L+    K     + DFGLAK
Sbjct: 957 DLAARNVLVHDDGKAK---VSDFGLAK 1028
>26711
          Length = 405

 Score = 43.5 bits (101), Expect = 2e-04,   Method: Composition-based stats.
 Identities = 18/45 (40%), Positives = 32/45 (71%)
 Frame = -2

Query: 111 QMISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKK 155
           Q++  ++++H++  +H D+KP N L+  G K + V +IDFGLA+K
Sbjct: 392 QVLDILQHVHAQGVVHMDLKPSNLLLS-GDKLDSVQLIDFGLARK 261
>30755
          Length = 1137

 Score = 43.1 bits (100), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 35/118 (29%), Positives = 53/118 (44%), Gaps = 1/118 (0%)
 Frame = +2

Query: 97  SRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKY 156
            R F+ +       ++IS + Y+HS+  I+RD+K +N L  L K G+ + + DFGL K  
Sbjct: 14  ERIFTEERTRFYGAEIISALGYLHSQGIIYRDLKLENLL--LDKDGH-IKVADFGLCK-- 178

Query: 157 RDARTHQHIPY-RENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPW 213
                 + I Y R  K   GT  Y +       +  R  D    G V+     G LP+
Sbjct: 179 ------EDITYGRTTKTFCGTPEYLAPEVLDDNDYGRAVDWWGTGVVMYEMICGRLPF 334
>03240
          Length = 1683

 Score = 42.4 bits (98), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 18/47 (38%), Positives = 28/47 (59%)
 Frame = -3

Query: 111 QMISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYR 157
           +++  IE +H   FIHRD+KPDN L+    +   + + DFGL   +R
Sbjct: 967 ELVQAIESVHRMGFIHRDIKPDNILID---RNGHIKLTDFGLCTGFR 836
>21808
          Length = 1011

 Score = 42.0 bits (97), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 49/198 (24%), Positives = 82/198 (41%), Gaps = 6/198 (3%)
 Frame = +1

Query: 35  VAIKLECVKTKHPQLHI-ESKIYKMMQGGVGIPTIRWCGAEGDYNVMVMELLGPSLEDLF 93
           VAIK     T  P+  + E++I K ++    I     C  +    ++   +   SL +  
Sbjct: 28  VAIKTLKSGTMDPKDFLAEAQIMKKLRHPKLIQLYAVCTQDDPIFIITELMKNGSLLEFL 207

Query: 94  NFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLA 153
               R   L  ++ +  Q+   + Y+ S+N+IHRD+   N L+      N V I DFGLA
Sbjct: 208 QGKGRVLKLPALIDIGAQIACGMAYLESQNYIHRDLAARNILVS---DNNTVKIADFGLA 378

Query: 154 KKYR----DARTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLM-YFNL 208
           +  +    +AR     P +       TA  A+      I    + D+ S G +L      
Sbjct: 379 RVIKEDEYEARVGARFPIK------WTAPEAANYNRFTI----KSDVWSFGILLTETVTY 528

Query: 209 GSLPWQGLKAATKRQKYE 226
           G +P+ G+  A    + E
Sbjct: 529 GRVPYPGMTNAEVLHQVE 582
>01392
          Length = 1806

 Score = 41.6 bits (96), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 36/127 (28%), Positives = 54/127 (42%), Gaps = 5/127 (3%)
 Frame = -1

Query: 94   NFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLA 153
            + C R+ SL     +   +   ++++HSK   HRD+KP+N L         V I DF LA
Sbjct: 1803 HLCEREASL-----VVRHIARALDFLHSKGIAHRDLKPENILCEHLDDVVPVKICDFDLA 1639

Query: 154  KKYRDARTHQHIPYRENKNLTGTARYAS---INTHLG--IEQSRRDDLESLGYVLMYFNL 208
                        P  E     G+A Y +   ++  +G      +R DL SLG +L     
Sbjct: 1638 SGISCDGDGTKTP--ELLTPVGSAEYMAPEVVDAWVGDSFSYDKRCDLWSLGIILYIMLC 1465

Query: 209  GSLPWQG 215
            G  P+ G
Sbjct: 1464 GYPPFYG 1444
>18921
          Length = 697

 Score = 41.2 bits (95), Expect = 8e-04,   Method: Compositional matrix adjust.
 Identities = 38/148 (25%), Positives = 67/148 (45%), Gaps = 3/148 (2%)
 Frame = +2

Query: 14  KIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQGGVGIPTIRWCGA 73
           K+G GS+G ++       G+ +AIK   V T   ++  E  I   MQ       +++ G+
Sbjct: 50  KLGEGSYGSVFKSLHKETGQVLAIKQVPVDTDLQEIIKEISI---MQQCDSKYIVKYYGS 220

Query: 74  --EGDYNVMVMELLGP-SLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVK 130
             +     +VME  G  S+ D+    ++    + +  +    +  + Y+HS+  IHRD+K
Sbjct: 221 YFKNTDLWIVMEYCGAGSVSDIMRLRNKTLVEREIATILYYTLKGLXYLHSRRKIHRDIK 400

Query: 131 PDNFLMGLGKKGNLVYIIDFGLAKKYRD 158
             N L+       L    DFG+A +  D
Sbjct: 401 AGNILLNNEGHAKLA---DFGVAGQLTD 475
>28638
          Length = 1458

 Score = 40.8 bits (94), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 30/106 (28%), Positives = 51/106 (48%), Gaps = 2/106 (1%)
 Frame = -1

Query: 109 ADQMISRIEYIHSK--NFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIP 166
           A Q+ + + ++ +   N IH D+KP+N L+    K + + I+DFG + +    R +Q+I 
Sbjct: 819 AQQLCTALLFLATPEMNIIHCDLKPENILLC-NPKRSAIKIVDFGSSCQLGQ-RIYQYIQ 646

Query: 167 YRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLP 212
            R          Y S    LG+      D+ SLG +L+  + G  P
Sbjct: 645 SR---------FYRSPEVLLGVPYDLAIDMWSLGCILVEMHTGEPP 535

 Score = 37.4 bits (85), Expect = 0.011,   Method: Compositional matrix adjust.
 Identities = 22/56 (39%), Positives = 31/56 (55%), Gaps = 3/56 (5%)
 Frame = -3

Query: 7    NRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHP---QLHIESKIYKMM 59
            +RY +   IG GSFG +    D    E+VAIK+  +K K P   Q  IE K+ ++M
Sbjct: 1147 DRYEIDSLIGKGSFGQVVKAYDHGDQEQVAIKI--IKNKKPFLNQAQIEVKLLELM 986
>27546
          Length = 426

 Score = 40.8 bits (94), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 23/49 (46%), Positives = 31/49 (63%)
 Frame = -1

Query: 111 QMISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDA 159
           QM   ++Y+HS +  HRD+K +N L  L K+ N V I DFG A+  RDA
Sbjct: 156 QMAKALQYLHSHDIAHRDLKCENIL--LSKRLN-VKIADFGFARYCRDA 19
>15910
          Length = 1361

 Score = 40.0 bits (92), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 24/98 (24%), Positives = 44/98 (44%)
 Frame = +2

Query: 116 IEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTG 175
           ++YIH+   +HRD+KP+N L       + + + DFGL++           P  +   + G
Sbjct: 503 VQYIHANGVVHRDLKPENLLYECMTDDSKLKLADFGLSRIIE--------PEVQMSTVCG 658

Query: 176 TARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPW 213
           T  Y +     G + +   D+ S+G +      G  P+
Sbjct: 659 TPGYCAPEVLKGDKYTPSVDMWSVGVIAYILLCGYEPF 772
>14420
          Length = 528

 Score = 40.0 bits (92), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 25/78 (32%), Positives = 39/78 (50%), Gaps = 2/78 (2%)
 Frame = +2

Query: 80  MVMELL-GPSLEDLFN-FCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMG 137
           +VME L G SL D+    C  +  +  V     + +  +E++H    IHRD+K DN L+G
Sbjct: 131 VVMEFLAGGSLTDVVTETCMDEGQIAAV---CRECLQALEFLHENQVIHRDIKSDNILLG 301

Query: 138 LGKKGNLVYIIDFGLAKK 155
           +      V + DFG   +
Sbjct: 302 MDGS---VKLTDFGFCAQ 346
>01966
          Length = 1735

 Score = 39.7 bits (91), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 22/70 (31%), Positives = 37/70 (52%), Gaps = 5/70 (7%)
 Frame = -1

Query: 111  QMISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYR---DARTHQHIP- 166
            Q+++ I + H +  +HRD+KP N L+        + I DFG+A+ +     A TH+ +  
Sbjct: 1384 QIVTGINFCHQRRIVHRDLKPQNLLIN---HTGAIKIADFGMARTFALPVRAYTHEVVTL 1214

Query: 167  -YRENKNLTG 175
             YR  + L G
Sbjct: 1213 WYRAPEILMG 1184
>26009
          Length = 886

 Score = 39.7 bits (91), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 12/26 (46%), Positives = 22/26 (84%)
 Frame = +3

Query: 111 QMISRIEYIHSKNFIHRDVKPDNFLM 136
           Q++S ++++HSK  +HRD+KP+N L+
Sbjct: 735 QLVSALDFMHSKQLVHRDIKPENVLI 812
>21800
          Length = 855

 Score = 39.7 bits (91), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 24/71 (33%), Positives = 40/71 (56%), Gaps = 4/71 (5%)
 Frame = +2

Query: 72  GAEGDYNVMVMELLGPSLEDLF---NFCSRKFSLKTVLLLADQMISRIEYIHSK-NFIHR 127
           G  G +  MV E+LG +L  L    N+  +   +  V L+  Q++  + Y+H+K N IH 
Sbjct: 536 GVNGTHVCMVFEVLGYNLLKLIIRSNY--QGIPVHNVKLIIRQVLEGLNYLHAKCNIIHT 709

Query: 128 DVKPDNFLMGL 138
           D+KP+N L+ +
Sbjct: 710 DIKPENILICV 742
>31885
          Length = 529

 Score = 38.1 bits (87), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 17/48 (35%), Positives = 31/48 (64%)
 Frame = -2

Query: 111 QMISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRD 158
           Q+   ++Y+ S+  +HRD+KPDN L  L ++G+  ++ DF +A +  D
Sbjct: 348 QLALVLDYLRSQKIVHRDIKPDNIL--LDEQGH-CHVTDFNIATQLED 214
>26560
          Length = 398

 Score = 38.1 bits (87), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 23/66 (34%), Positives = 38/66 (57%)
 Frame = -1

Query: 100 FSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDA 159
           F+ K V   A +++  +E++HS+  ++RD+KP N L  L + G+ V I D GLA  +   
Sbjct: 365 FTEKEVRFYAAEVMLGLEHMHSRFVVYRDLKPANIL--LDENGH-VRISDLGLACDFSKK 195

Query: 160 RTHQHI 165
           R H  +
Sbjct: 194 RPHASV 177
>17975
          Length = 449

 Score = 38.1 bits (87), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 38/153 (24%), Positives = 63/153 (41%), Gaps = 19/153 (12%)
 Frame = +3

Query: 20  FGDIYLGTDIAAGEEVAIKL------------------ECVK-TKHPQLHIESKIYKMMQ 60
           F  + L   +  GE+VA+K+                   C+K  +HP +    ++Y+++ 
Sbjct: 6   FAVVKLARHVFTGEKVAVKVIDKTKLDEVSRSHLFQEVRCMKLVQHPNV---VRLYEVID 176

Query: 61  GGVGIPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIH 120
               +  I   G  GD    +M   G   E L     R F          Q++  I Y H
Sbjct: 177 TQTKLYLILELGDGGDMYDYIMRHSGGLEEKL---AKRYFR---------QIVEAISYCH 320

Query: 121 SKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLA 153
             + +HRD+KP+N +    +K  LV + DFG +
Sbjct: 321 KLHVVHRDLKPENVV--FFEKPGLVKLTDFGFS 413
>19301
          Length = 712

 Score = 38.1 bits (87), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 41/140 (29%), Positives = 67/140 (47%), Gaps = 3/140 (2%)
 Frame = +2

Query: 15  IGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQ-GGVGIPTIRWCGA 73
           +GSG+ G ++LG   A  EEVA+K    K +  +   E+ I  + +     I + +    
Sbjct: 329 LGSGAQGAVFLGKLCA--EEVAVK----KVRDIK---ETDIRNLRKLNHPNIISFKGVCT 481

Query: 74  EGDYNVMVMELL--GPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKP 131
           +     ++ME    G   E L +   ++     VL  + Q+ S + Y+HS   IHRD+K 
Sbjct: 482 QAPCYCIIMEYCPYGQLYEVLRD--GKEIPPALVLDWSKQIASGMNYLHSHKIIHRDLKS 655

Query: 132 DNFLMGLGKKGNLVYIIDFG 151
            N L+    K ++V I DFG
Sbjct: 656 PNVLVA---KNDVVKISDFG 706
>27405
          Length = 532

 Score = 37.4 bits (85), Expect = 0.010,   Method: Compositional matrix adjust.
 Identities = 22/66 (33%), Positives = 38/66 (57%)
 Frame = -3

Query: 100 FSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDA 159
           F+ K V   A +++  +E++HS+  ++RD+KP N L  L + G+ V I D GLA  +   
Sbjct: 263 FTEKEVRFYAAEVMLGLEHMHSRFVVYRDLKPANIL--LDENGH-VRISDLGLACDFSKK 93

Query: 160 RTHQHI 165
           + H  +
Sbjct: 92  KPHASV 75
>18484
          Length = 635

 Score = 37.4 bits (85), Expect = 0.010,   Method: Compositional matrix adjust.
 Identities = 38/153 (24%), Positives = 65/153 (42%), Gaps = 8/153 (5%)
 Frame = +1

Query: 99  KFSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKK--Y 156
           KF        A ++   + ++H +  I+RD+K DN +  L  +G+ + I DFG+ K+   
Sbjct: 31  KFKEPVAAFYAAEIAVGLFFLHDQGIIYRDLKLDNVM--LDSEGH-IKIADFGMCKEGMT 201

Query: 157 RDARTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGL 216
            DA T         +   GT  Y +    L    S+  D  + G +L     G  P+ G 
Sbjct: 202 GDATT---------RTFCGTPDYIAPEIVLYQPYSKSVDWWAYGVLLFEMLAGQPPFDG- 351

Query: 217 KAATKRQKYERISEKKMSTPIEV------LCKG 243
               + + +  I++  +S P  +      LCKG
Sbjct: 352 --EDEDELFSSITDHNVSYPKAMSREAVSLCKG 444
>12786
          Length = 460

 Score = 37.4 bits (85), Expect = 0.011,   Method: Compositional matrix adjust.
 Identities = 16/51 (31%), Positives = 31/51 (60%)
 Frame = -3

Query: 111 QMISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDART 161
           +M+  ++ +H++  IH D+KP NF++  G     + +IDFG+A   +  +T
Sbjct: 386 EMLRAVKALHNEGVIHSDLKPANFMLVAGN----LKLIDFGIANTLQQDKT 246
>01707
          Length = 757

 Score = 37.0 bits (84), Expect = 0.014,   Method: Compositional matrix adjust.
 Identities = 45/165 (27%), Positives = 67/165 (40%), Gaps = 24/165 (14%)
 Frame = +1

Query: 14  KIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQGGVGIPTIRWCGA 73
           KIG GS+G ++   +    + VAIK            +ES+   +++  + +  IR    
Sbjct: 85  KIGEGSYGVVFKCRNKETSQLVAIKK----------FVESEDDPLIKK-IAMREIR---- 219

Query: 74  EGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQ----------------MISRIE 117
                 M+ +L  P+L  L     RK  L  V    D                 M+ RI 
Sbjct: 220 ------MLKQLKHPNLVRLIEVFRRKKRLHLVFDYVDHTLLNELDRYPRGLPEPMVKRII 381

Query: 118 Y--------IHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAK 154
           Y         H  N IHRDVKP+N L  + ++G  V + DFG A+
Sbjct: 382 YQTLLAVNFCHQYNTIHRDVKPENIL--ITRQGQ-VKLCDFGFAR 507
>12721
          Length = 821

 Score = 36.6 bits (83), Expect = 0.021,   Method: Compositional matrix adjust.
 Identities = 43/192 (22%), Positives = 78/192 (40%), Gaps = 1/192 (0%)
 Frame = +1

Query: 14  KIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQGGVGIPTIRWCGA 73
           KIG GS G + + T     +    K++  K +  +L     +         I  +     
Sbjct: 109 KIGEGSTGIVCIATSRDGRQMAVKKMDLRKQQRRELLFNEVVVMRDYHHPNIVEMYNSYL 288

Query: 74  EGDYNVMVMELL-GPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKPD 132
             D   +VME + G +L D+    + +     +  +    +  + ++H+   IHRD+K D
Sbjct: 289 VNDELWVVMEFMEGGALTDIVT--NNRMDEVQIATVCRACLKALAFLHANGVIHRDIKSD 462

Query: 133 NFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASINTHLGIEQSR 192
           + L+    K   V + DFG       A+  Q +  R  K+L GT  + +      +    
Sbjct: 463 SILLSHDGK---VKLXDFGFC-----AQVTQDLQKR--KSLVGTPYWMAPEVISRLPYGP 612

Query: 193 RDDLESLGYVLM 204
             D+ SLG ++M
Sbjct: 613 EVDIWSLGIMVM 648
>36481
          Length = 806

 Score = 36.2 bits (82), Expect = 0.028,   Method: Compositional matrix adjust.
 Identities = 28/137 (20%), Positives = 61/137 (44%), Gaps = 8/137 (5%)
 Frame = +2

Query: 7   NRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKL-ECVKTKHPQLHIESKIYKMMQGG--- 62
           N  +L    G G+FG +    D+  G+++A+K+ + V        +E  + + ++     
Sbjct: 362 NDMKLCPHWGEGTFGKVVQCKDLLKGDDIALKIIKNVDKYREAAKLEINVLEKLREKDPH 541

Query: 63  ---VGIPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSR-KFSLKTVLLLADQMISRIEY 118
              + +  + W    G +  +   +LG S+ D     S   + ++ V  ++ Q+   + +
Sbjct: 542 AKHMCVQMLDWFDYHG-HVCISFHMLGLSVFDFLKDNSYGAYPIEQVRHISYQLCYAVNF 718

Query: 119 IHSKNFIHRDVKPDNFL 135
           +H     H D+KP+N L
Sbjct: 719 LHENQLTHTDLKPENIL 769
>31489
          Length = 329

 Score = 35.8 bits (81), Expect = 0.032,   Method: Composition-based stats.
 Identities = 13/25 (52%), Positives = 19/25 (76%)
 Frame = +3

Query: 111 QMISRIEYIHSKNFIHRDVKPDNFL 135
           Q++  ++YIHS N +HRD+KP N L
Sbjct: 189 QILRGLKYIHSANVVHRDLKPSNLL 263
>04138
          Length = 800

 Score = 35.4 bits (80), Expect = 0.039,   Method: Compositional matrix adjust.
 Identities = 20/56 (35%), Positives = 32/56 (57%)
 Frame = +1

Query: 101 SLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKY 156
           S K++   AD+   R+ YIH    +HRD+K  N L+    K  ++ + DFGLA+ +
Sbjct: 16  SKKSIC*AADE---RLYYIHRNKILHRDMKAANILI---TKQGVLKLADFGLARAF 165
>09277
          Length = 518

 Score = 35.0 bits (79), Expect = 0.049,   Method: Compositional matrix adjust.
 Identities = 14/37 (37%), Positives = 22/37 (59%)
 Frame = -1

Query: 208 LGSLPWQGLKAATKRQKYERISEKKMSTPIEVLCKGY 244
           L  LPWQ   A+ K Q++E    ++ S PI +LC+ +
Sbjct: 230 LVQLPWQSAVASAKFQQFESSHSQEFSNPIHLLCRDH 120
>03508
          Length = 1463

 Score = 34.3 bits (77), Expect = 0.087,   Method: Compositional matrix adjust.
 Identities = 16/46 (34%), Positives = 29/46 (63%)
 Frame = +1

Query: 111 QMISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKY 156
           +++  +++ HS   +HRDVKP N ++    K   + +ID+GLA+ Y
Sbjct: 895 ELMKALDFCHSMGIMHRDVKPHNVMIDHENKK--LRLIDWGLAEFY 1026
>07940
          Length = 1336

 Score = 33.5 bits (75), Expect = 0.15,   Method: Compositional matrix adjust.
 Identities = 29/112 (25%), Positives = 52/112 (46%), Gaps = 1/112 (0%)
 Frame = -3

Query: 103 KTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTH 162
           K ++  A Q+   +EY+ SK  IHRD+   N L+    +  ++ I DFGL +  +     
Sbjct: 347 KDLISYAYQVARGMEYLASKQCIHRDLAARNVLVA---EEYVLKIADFGLTRNLQ----- 192

Query: 163 QHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLM-YFNLGSLPW 213
           Q   YR+  +     ++ +       + + + D+ S G +L   F LG  P+
Sbjct: 191 QFDYYRKTTDGRLPVKWMAPEALFDRKYTSKSDVWSYGVLLWEIFTLGGNPY 36
>28157
          Length = 400

 Score = 33.5 bits (75), Expect = 0.16,   Method: Composition-based stats.
 Identities = 22/50 (44%), Positives = 27/50 (54%), Gaps = 3/50 (6%)
 Frame = +3

Query: 116 IEYIHS---KNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTH 162
           +EY+H    K  IHRD+KP N L  L + G  + I DFG A    D  TH
Sbjct: 255 VEYLHGMKPKALIHRDLKPPNLL--LIQCGTKLKICDFGTAC---DIHTH 389
>13212
          Length = 1067

 Score = 32.3 bits (72), Expect = 0.36,   Method: Compositional matrix adjust.
 Identities = 26/103 (25%), Positives = 49/103 (47%), Gaps = 7/103 (6%)
 Frame = -1

Query: 111 QMISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYREN 170
           +M   ++++H  + IHRD+K  N L+ +  +   V + DFG++ K  + +T Q     + 
Sbjct: 956 EMCMALDFLHRHHVIHRDIKAGNVLLTIDGE---VKLADFGVSAK--NTQTQQ-----KR 807

Query: 171 KNLTGTARYASINTHLGIEQSRRD-------DLESLGYVLMYF 206
               GT  + +    L   ++ +D       D+ SLG  L+ F
Sbjct: 806 DTFIGTPYWMAPEVVLC--ETLKDTPYDFKADIWSLGVTLIEF 684
>13066
          Length = 551

 Score = 32.0 bits (71), Expect = 0.52,   Method: Compositional matrix adjust.
 Identities = 22/71 (30%), Positives = 36/71 (50%)
 Frame = +3

Query: 111 QMISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYREN 170
           QM + + Y+HS +  HRD+K +N L  L    N V + DFG A         +++    +
Sbjct: 300 QMTTALNYLHSYDVAHRDLKCENIL--LSSHFN-VKLADFGFACACITESGEKYM----S 458

Query: 171 KNLTGTARYAS 181
           +   G+A YA+
Sbjct: 459 RTYCGSAAYAA 491
>19094
          Length = 898

 Score = 31.6 bits (70), Expect = 0.62,   Method: Compositional matrix adjust.
 Identities = 19/71 (26%), Positives = 36/71 (50%)
 Frame = +1

Query: 88  SLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYI 147
           S+ D+    ++    + +  +    +  + Y+HS+  IHRD+K  N L  L  +G+   +
Sbjct: 13  SVSDIMRLRNKTLVEREIATILYYTLKGL*YLHSRRKIHRDIKAGNIL--LNNEGH-AKL 183

Query: 148 IDFGLAKKYRD 158
            DFG+A +  D
Sbjct: 184 ADFGVAGQLTD 216
>29360
          Length = 363

 Score = 30.8 bits (68), Expect = 1.1,   Method: Composition-based stats.
 Identities = 17/69 (24%), Positives = 33/69 (47%), Gaps = 3/69 (4%)
 Frame = +3

Query: 71  CGAEGDYNVMVMELLGPSLEDLFNFCSRKFS---LKTVLLLADQMISRIEYIHSKNFIHR 127
           C    ++  +V E+L  +L D       KF    LK +  +  Q+++ +  +     IH 
Sbjct: 159 CFQHKNHTCLVFEMLEQNLYDFLK--QNKFQPLPLKYIRPITQQVLTALRKLKQLGLIHA 332

Query: 128 DVKPDNFLM 136
           D+KP+N ++
Sbjct: 333 DLKPENIML 359
>19761
          Length = 473

 Score = 30.4 bits (67), Expect = 1.4,   Method: Compositional matrix adjust.
 Identities = 28/95 (29%), Positives = 42/95 (44%), Gaps = 2/95 (2%)
 Frame = -3

Query: 111 QMISRIEYIHSKN--FIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYR 168
           Q  S + Y+H+     +HRD+KP N    + +KG+ V + D GLA+K          P  
Sbjct: 399 QTASALNYMHTHTPVILHRDLKPQNIY--VTEKGD-VRLGDLGLARKLTG-------PAD 250

Query: 169 ENKNLTGTARYASINTHLGIEQSRRDDLESLGYVL 203
              +  GT  Y S         + + D+ SLG V 
Sbjct: 249 FATSQVGTIMYLSPEILSQQPYNSKSDIWSLGCVF 145
>37602
          Length = 804

 Score = 29.6 bits (65), Expect = 2.5,   Method: Compositional matrix adjust.
 Identities = 19/79 (24%), Positives = 39/79 (49%)
 Frame = -1

Query: 86  GPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLV 145
           G S++D+++  +   +   +  +  + +  + Y+H +  +HRD+K  N L  L ++G   
Sbjct: 267 GGSMQDIYH-VTGPLTEPQIAFVCRETLKGLHYLHRRGKMHRDIKGANIL--LTEEG--- 106

Query: 146 YIIDFGLAKKYRDARTHQH 164
              D  LA  +R +  H H
Sbjct: 105 ---DVKLADFWRVSSNHSH 58
>32359
          Length = 928

 Score = 28.1 bits (61), Expect = 7.6,   Method: Compositional matrix adjust.
 Identities = 18/49 (36%), Positives = 27/49 (55%), Gaps = 2/49 (4%)
 Frame = -1

Query: 9   YRLGRKIGSGSFGDIYLGTDIAAGEEVAIK--LECVKTKHPQLHIESKI 55
           Y   + IG+GSFG +Y    +   E VAIK  L+  + K+ +L I  K+
Sbjct: 424 YTDAKVIGNGSFGVVYQAKLVDTSELVAIKKVLQDKRFKNRELQIMRKL 278
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6678481|ref|NP_033482.1| ubiquitin-conjugating enzyme
E2L 3 [Mus musculus]
         (154 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

18592                                                                 170   3e-43
21443                                                                  84   2e-17
31099                                                                  83   4e-17
02313                                                                  62   9e-11
02183                                                                  59   6e-10
37111                                                                  58   1e-09
34525                                                                  53   6e-08
04905                                                                  52   1e-07
12485                                                                  47   4e-06
02740                                                                  44   2e-05
39424                                                                  43   4e-05
38163                                                                  41   3e-04
14380                                                                  40   5e-04
19311                                                                  40   6e-04
05633                                                                  35   0.016
13254                                                                  32   0.099
26740                                                                  27   4.9  
>18592
          Length = 475

 Score =  170 bits (430), Expect = 3e-43,   Method: Compositional matrix adjust.
 Identities = 80/130 (61%), Positives = 99/130 (76%), Gaps = 1/130 (0%)
 Frame = +2

Query: 1   MAASRRLMKELEEIRK-CGMKNFRNIQVDEANLLTWQGLIVPDNPPYDKGAFRIEINFPA 59
           MAA+RRL KEL++IRK    K FR    DE+N+L W+ ++VP+NPPY+KG F ++INFPA
Sbjct: 86  MAATRRLTKELQDIRKEASQKAFRIKDQDESNILHWEVVLVPENPPYNKGTFTVDINFPA 265

Query: 60  EXXXXXXXXXXXXXXXHPNIDEKGQVCLPVISAENWKPATKTDQVIQSLIALVNDPQPEH 119
           E               HPN+DEKGQVCLP+ISAENWKPATKTDQV+ +LI L+N+P+PEH
Sbjct: 266 EYPFKPPKVTFKTKIYHPNVDEKGQVCLPIISAENWKPATKTDQVLTALIGLINEPEPEH 445

Query: 120 PLRADLAEEY 129
           PLRADLAEEY
Sbjct: 446 PLRADLAEEY 475
>21443
          Length = 610

 Score = 84.3 bits (207), Expect = 2e-17,   Method: Compositional matrix adjust.
 Identities = 46/147 (31%), Positives = 78/147 (53%), Gaps = 1/147 (0%)
 Frame = -1

Query: 3   ASRRLMKELEEIRKCGMKNFRNIQVDEANLLTWQGLIV-PDNPPYDKGAFRIEINFPAEX 61
           A +R+ KEL+++ K          V E ++  WQ  I+ P +  Y+ G F + I+FP + 
Sbjct: 532 AMKRINKELQDLGKDPPAQCSAGPVGE-DMFQWQATIMGPRDSAYEGGVFFLTISFPTDY 356

Query: 62  XXXXXXXXXXXXXXHPNIDEKGQVCLPVISAENWKPATKTDQVIQSLIALVNDPQPEHPL 121
                         HPNI+  G +CL ++ ++ W PA    +V+ S+ +++ DP P+ PL
Sbjct: 355 PFKPPKVSFTTRIYHPNINSNGSICLDILRSQ-WSPALTISKVLLSICSMLTDPNPDDPL 179

Query: 122 RADLAEEYSKDRKKFCKNAEEFTKKYG 148
             ++A  Y  DR+KF +NA+ +T KY 
Sbjct: 178 VPEIARIYKTDREKFYENAKIWTNKYA 98
>31099
          Length = 748

 Score = 83.2 bits (204), Expect = 4e-17,   Method: Compositional matrix adjust.
 Identities = 45/145 (31%), Positives = 75/145 (51%), Gaps = 1/145 (0%)
 Frame = +2

Query: 5   RRLMKELEEIRKCGMKNFRNIQVDEANLLTWQGLIV-PDNPPYDKGAFRIEINFPAEXXX 63
           + L KEL+++ +    N     V + +   WQ  I+ P+  PY  G F + I FPA+   
Sbjct: 101 KDLQKELQDLGRDPPANCSAGPVGD-DFFHWQATIMGPNKSPYQGGVFFLTITFPADYPF 277

Query: 64  XXXXXXXXXXXXHPNIDEKGQVCLPVISAENWKPATKTDQVIQSLIALVNDPQPEHPLRA 123
                       HPNI+  G +CL ++ ++ W PA    +V+ S+ +L+ DP P+ PL  
Sbjct: 278 KPPKVAFTTKIYHPNINSNGSICLDILRSQ-WSPALTISKVLLSISSLLTDPNPDDPLVP 454

Query: 124 DLAEEYSKDRKKFCKNAEEFTKKYG 148
           ++A  Y  DR K+ +  +E+T+KY 
Sbjct: 455 EIARVYKNDRHKYEQLGKEWTQKYA 529
>02313
          Length = 891

 Score = 62.0 bits (149), Expect = 9e-11,   Method: Compositional matrix adjust.
 Identities = 37/153 (24%), Positives = 67/153 (43%), Gaps = 13/153 (8%)
 Frame = -1

Query: 2   AASRRLMKELEEIRKCGMKNFRNIQVDEANLLTWQ-GLIVPDNPPYDKGAFRIEINFPAE 60
            A + L  EL++I+   ++ FR   +++ N+  W+  +  P    Y+ G F+  + FPA+
Sbjct: 768 GAVKALQLELKKIQAEPVEGFRVKLINDDNIFEWEVAIFGPPGTLYEGGYFKAHMKFPAD 589

Query: 61  XXXXXXXXXXXXXXXHPNIDEKGQVCLPVIS------------AENWKPATKTDQVIQSL 108
                          HPN+ E G+VC+ ++             +E W P      ++ S+
Sbjct: 588 YPYSPPSVRFITKMWHPNVYENGEVCISILHPPVDDPQSGELPSERWNPTQTVRTILLSI 409

Query: 109 IALVNDPQPEHPLRADLAEEYSKDRKKFCKNAE 141
           I+L+N+P    P   D +  Y K +    K  E
Sbjct: 408 ISLLNEPNTYSPANVDASVMYRKWKDTXGKEKE 310
>02183
          Length = 1456

 Score = 59.3 bits (142), Expect = 6e-10,   Method: Compositional matrix adjust.
 Identities = 39/151 (25%), Positives = 72/151 (47%), Gaps = 7/151 (4%)
 Frame = -2

Query: 7    LMKELEEIRKCGMKNFRNIQVDEANLLTWQGL-IVPDNPPYDKGAFRIEINFPAEXXXXX 65
            L+KE++E+ +  M     +Q D+ ++L    L + PD   +  G F+ +IN P E     
Sbjct: 1278 LVKEVQEMEE-NMPRTCKVQFDDPSVLHHFILNVTPDEGYWTGGKFKFDINVPEEYNIVP 1102

Query: 66   XXXXXXXXXXHPNIDEKGQVCLPVISAEN-----WKPATKTDQVIQSLIALVND-PQPEH 119
                      HPNI E G++CL ++   +     W P  +   V+  L +L +D    E 
Sbjct: 1101 PKAVCHTKIWHPNITEAGEICLSLLRQNSYDGLGWAPTRRLKDVVWGLNSLFSDLLNFED 922

Query: 120  PLRADLAEEYSKDRKKFCKNAEEFTKKYGEK 150
            PL  + AE +++D++ F     ++ + Y ++
Sbjct: 921  PLNVEAAEHFARDKESFKIKVRDYIQAYAKR 829
>37111
          Length = 611

 Score = 58.2 bits (139), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 41/151 (27%), Positives = 68/151 (45%), Gaps = 4/151 (2%)
 Frame = -1

Query: 3   ASRRLMKELEEIRKCGMKNFRNIQVD--EANLLTWQGLIV-PDNPPYDKGAFRIEINFPA 59
           A +R+ +E +E+ K        I+VD  +  L   +G I+ P   PY+ G F ++I  P 
Sbjct: 491 AQQRIQREFKEVVKSAEVTQAAIKVDFVDGMLTHLKGEIMGPPETPYEGGRFELDIRIPE 312

Query: 60  EXXXXXXXXXXXXXXXHPNIDE-KGQVCLPVISAENWKPATKTDQVIQSLIALVNDPQPE 118
                           HPN+    G +CL ++  + W  A     V+ SL AL+   +P+
Sbjct: 311 TYPFNPPLVKFLTKIWHPNVSSVTGAICLDILK-DQWAAAMTLRTVLLSLQALMAAAEPD 135

Query: 119 HPLRADLAEEYSKDRKKFCKNAEEFTKKYGE 149
            P  A +A +Y   R+ F K A  +T  + +
Sbjct: 134 DPQDAVVANQYKDHRELFNKTARHWTSAFAQ 42
>34525
          Length = 561

 Score = 52.8 bits (125), Expect = 6e-08,   Method: Compositional matrix adjust.
 Identities = 27/76 (35%), Positives = 40/76 (52%), Gaps = 3/76 (3%)
 Frame = -1

Query: 76  HPNIDEKGQVCLPVISAE---NWKPATKTDQVIQSLIALVNDPQPEHPLRADLAEEYSKD 132
           HPNID  G++CL  +       WKP      V+ SL  L+  P P+  L AD+A E+   
Sbjct: 315 HPNIDNAGRICLDTLKMPPKGAWKPCMNLMTVLTSLQLLMATPNPDDALMADIASEFKHT 136

Query: 133 RKKFCKNAEEFTKKYG 148
            + F + A +FTK++ 
Sbjct: 135 PELFRQKAVQFTKQHA 88
>04905
          Length = 1868

 Score = 52.0 bits (123), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 31/110 (28%), Positives = 49/110 (44%), Gaps = 2/110 (1%)
 Frame = -1

Query: 41   PDNPPYDKGAFRIEINFPAEXXXXXXXXXXXXXXXHPNIDE-KGQVCLPVISAENWKPAT 99
            P + PY+ G +++ ++ P                 HPNIDE  G VCL VI+ + W    
Sbjct: 1661 PPSTPYEGGVWKVRVDLPERYPFKSPSIGFINRIYHPNIDEVSGTVCLDVIN-QAWTALY 1485

Query: 100  KTDQVIQSLI-ALVNDPQPEHPLRADLAEEYSKDRKKFCKNAEEFTKKYG 148
                + +S +  L+  P P  PL  D A  Y     ++ K  EE+ +K+ 
Sbjct: 1484 DLSNIFESFLPQLLTYPNPVDPLNGDAAALYLHRPDEYKKKVEEYVQKFA 1335
>12485
          Length = 652

 Score = 47.0 bits (110), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 30/106 (28%), Positives = 46/106 (43%), Gaps = 9/106 (8%)
 Frame = +1

Query: 41  PDNPPYDKGAFRIEINFPAEXXXXXXXXXXXXXXXHPNIDE-KGQVCLPVISAENWKPAT 99
           P + PY+ G +++ ++ P +               HPNIDE  G VCL VI+ + W    
Sbjct: 34  PPSTPYEGGVWKVRVDLPEKYPFKSPSIGFMNRIYHPNIDEVSGTVCLDVIN-QAWTALY 210

Query: 100 KTDQVIQSLIA-LVNDPQPEHPLRADLA-------EEYSKDRKKFC 137
               + +S +  L+  P P  PL  D A       E+Y K   + C
Sbjct: 211 DLSNIFESFLPQLLTYPNPIDPLNGDAAALYLHKPEDYKKKSSRLC 348
>02740
          Length = 2287

 Score = 43.9 bits (102), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 32/130 (24%), Positives = 51/130 (39%), Gaps = 4/130 (3%)
 Frame = -1

Query: 2    AASRRLMKELEEIRKC---GMKNFRNIQVDEANLLTWQGLI-VPDNPPYDKGAFRIEINF 57
               +RL +EL  +      G+  F     D  NL  W G I       Y+   +++ + F
Sbjct: 2005 TVGKRLQQELRTLMMSSDPGVSAFP----DGDNLFKWVGTIEGAKGTVYEGLQYKLVLEF 1838

Query: 58   PAEXXXXXXXXXXXXXXXHPNIDEKGQVCLPVISAENWKPATKTDQVIQSLIALVNDPQP 117
            P+                HPN+D  G +CL ++  E W        V+ S+ +L+ +P  
Sbjct: 1837 PSGYPYQAVSVRFSTPCFHPNVDNHGNICLDILK-EKWSALYDVRTVLLSIQSLLAEPNN 1661

Query: 118  EHPLRADLAE 127
              PL    AE
Sbjct: 1660 VSPLNXHAAE 1631
>39424
          Length = 1749

 Score = 43.1 bits (100), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 21/83 (25%), Positives = 41/83 (49%), Gaps = 12/83 (14%)
 Frame = -2

Query: 76   HPNIDEKGQVCLPVI------------SAENWKPATKTDQVIQSLIALVNDPQPEHPLRA 123
            HPNID +G VC+ ++            ++E W P    + ++ S+I+++ DP  E P   
Sbjct: 1460 HPNIDPEGNVCISILHEPGDDKYGYEKASERWLPIHTVETILVSVISMLADPNDESPANV 1281

Query: 124  DLAEEYSKDRKKFCKNAEEFTKK 146
            D A+ + +  ++F K      ++
Sbjct: 1280 DAAKMWREQPEEFKKRVSRCVRR 1212
>38163
          Length = 2214

 Score = 40.8 bits (94), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 27/118 (22%), Positives = 51/118 (43%), Gaps = 2/118 (1%)
 Frame = -3

Query: 31   NLLTWQGLI-VPDNPPYDKGAFRIEINFPAEXXXXXXXXXXXXXXXHPNIDEKGQVCLPV 89
            NL  W+  I       ++ G F + + F  +               HPN+   G VCL +
Sbjct: 1678 NLFNWECKIPGKKGTMWEGGLFSLRMLFKEDYPSTPPKCKFEPPLFHPNVYPSGTVCLSL 1499

Query: 90   ISAE-NWKPATKTDQVIQSLIALVNDPQPEHPLRADLAEEYSKDRKKFCKNAEEFTKK 146
            +  E +W+PA    Q++  +  L+N+   + P +A+    Y       C+N+ E+ ++
Sbjct: 1498 LDEEKDWRPAVTIKQILLGIQELLNECNVKDPAQAEAYTIY-------CQNSSEYERR 1346
>14380
          Length = 1522

 Score = 39.7 bits (91), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 24/115 (20%), Positives = 48/115 (41%), Gaps = 1/115 (0%)
 Frame = +3

Query: 41  PDNPPYDKGAFRIEINFPAEXXXXXXXXXXXXXXXHPNIDEKGQVCLPVISAENWKPATK 100
           P   PY  G FR+++                    HPN+   G++C+  +   +WKP   
Sbjct: 228 PAGTPYAGGLFRMKLVLSKSFPSEPPKAFFITKIFHPNVASNGEICVNTLK-RDWKPELG 404

Query: 101 TDQVIQSLIALVNDPQPEHPLRADLAEEYSKDRKKFCKNAEEFTKKYGEK-RPVD 154
              ++ ++  L+  P PE  L  +  +   +  + +   A+ FT+ + +  RP +
Sbjct: 405 IKHILLTVKCLLIVPNPESALNEEAGKLLLEQYEDYSMRAKMFTEIHAKPLRPTE 569
>19311
          Length = 1071

 Score = 39.7 bits (91), Expect = 6e-04,   Method: Compositional matrix adjust.
 Identities = 28/122 (22%), Positives = 44/122 (36%), Gaps = 8/122 (6%)
 Frame = -2

Query: 35  WQGLIVPDNPPYDK--------GAFRIEINFPAEXXXXXXXXXXXXXXXHPNIDEKGQVC 86
           W G +    PP           G F + +  P                 HPNI   G V 
Sbjct: 524 WTGTVATGRPPSQGPRAVRXKGGWFLLYLQIPHSYPMRPPKVRFITKIFHPNISRHGDVG 345

Query: 87  LPVISAENWKPATKTDQVIQSLIALVNDPQPEHPLRADLAEEYSKDRKKFCKNAEEFTKK 146
           L  I   NW  A    +V+ S+ +++ DP     +   +   Y + + +F + A  +T K
Sbjct: 344 LDSIH-HNWSLALTISKVLISIQSVLTDPYCHVCMEPKIGALYQRAKPEFERIARRWTWK 168

Query: 147 YG 148
           Y 
Sbjct: 167 YA 162
>05633
          Length = 1150

 Score = 34.7 bits (78), Expect = 0.016,   Method: Compositional matrix adjust.
 Identities = 11/39 (28%), Positives = 24/39 (61%)
 Frame = +3

Query: 76  HPNIDEKGQVCLPVISAENWKPATKTDQVIQSLIALVND 114
           HP++   G +CL +++ E+W PA     V  S++++++ 
Sbjct: 177 HPHVYSNGHICLSILT-EDWSPALSVQSVCLSIVSMLSS 290
>13254
          Length = 870

 Score = 32.0 bits (71), Expect = 0.099,   Method: Compositional matrix adjust.
 Identities = 13/46 (28%), Positives = 25/46 (54%)
 Frame = +2

Query: 76  HPNIDEKGQVCLPVISAENWKPATKTDQVIQSLIALVNDPQPEHPL 121
           HPN+   G++C+  +  ++WKP      ++ ++  L+  P PE  L
Sbjct: 200 HPNVASNGEICVNTLK-KDWKPDLGIKHILLTIKCLLIVPNPESAL 334
>26740
          Length = 404

 Score = 26.6 bits (57), Expect = 4.9,   Method: Compositional matrix adjust.
 Identities = 17/61 (27%), Positives = 30/61 (49%), Gaps = 4/61 (6%)
 Frame = +2

Query: 2   AASRRLMKELEEIRKCGMKNFRN---IQVDEANLLTWQGLIV-PDNPPYDKGAFRIEINF 57
           A +RRL +E   +      ++ +   ++ D+  L   + LI  P + PY  GAF  ++ F
Sbjct: 185 ARTRRLAQEAVTLSTSLPLSYNSSVFVRCDDERLDIMKVLITGPSDTPYANGAFEFDVYF 364

Query: 58  P 58
           P
Sbjct: 365 P 367
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6679593|ref|NP_033027.1| RAB3A, member RAS oncogene
family [Mus musculus]
         (220 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

33380                                                                 165   3e-43
08428                                                                 124   4e-29
34468                                                                 112   1e-25
05468                                                                 112   1e-25
26083                                                                 108   2e-24
33374                                                                  96   2e-24
07465                                                                 106   9e-24
17511                                                                  96   8e-21
07580                                                                  96   2e-20
13901                                                                  95   2e-20
33794                                                                  91   4e-19
01398                                                                  89   2e-18
14456                                                                  88   3e-18
13750                                                                  86   1e-17
11257                                                                  84   3e-17
30760                                                                  82   2e-16
26536                                                                  81   3e-16
32723                                                                  81   4e-16
01972                                                                  69   2e-15
34597                                                                  70   4e-14
12339                                                                  72   2e-13
19006                                                                  70   6e-13
11728                                                                  69   1e-12
35581                                                                  63   7e-11
19046                                                                  63   1e-10
24619                                                                  61   3e-10
13745                                                                  61   3e-10
34359                                                                  61   4e-10
27191                                                                  58   3e-09
31291                                                                  57   5e-09
00858                                                                  55   2e-08
19656                                                                  54   4e-08
01095                                                                  54   6e-08
09204                                                                  53   9e-08
08153                                                                  51   3e-07
00552                                                                  50   9e-07
09827                                                                  47   4e-06
14775                                                                  45   2e-05
29380                                                                  45   3e-05
14119                                                                  42   2e-04
10862                                                                  39   0.001
33605                                                                  37   0.004
25796                                                                  34   0.036
06411                                                                  31   0.38 
10708                                                                  31   0.38 
06994                                                                  29   1.5  
18184                                                                  29   1.9  
31928                                                                  28   2.4  
>33380
          Length = 282

 Score =  165 bits (417), Expect(2) = 3e-43,   Method: Compositional matrix adjust.
 Identities = 74/82 (90%), Positives = 80/82 (97%)
 Frame = +3

Query: 63  TIYRNDKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEESFNAVQDWSTQIKT 122
           T++R DKR+KLQIWDTAGQERYRTITTAYYRGAMGFILMYD+TNEESFNAVQDW TQIKT
Sbjct: 36  TVFRQDKRVKLQIWDTAGQERYRTITTAYYRGAMGFILMYDVTNEESFNAVQDWCTQIKT 215

Query: 123 YSWDNAQVLLVGNKCDMEDERV 144
           YSWDNAQV+LVGNKCD+EDERV
Sbjct: 216 YSWDNAQVVLVGNKCDLEDERV 281

 Score = 27.3 bits (59), Expect(2) = 3e-43,   Method: Compositional matrix adjust.
 Identities = 11/14 (78%), Positives = 13/14 (92%)
 Frame = +2

Query: 51 FVSTVGIDFKVKTI 64
          FVSTVGIDFKV ++
Sbjct: 2  FVSTVGIDFKVNSL 43
>08428
          Length = 1109

 Score =  124 bits (310), Expect = 4e-29,   Method: Compositional matrix adjust.
 Identities = 54/156 (34%), Positives = 94/156 (60%)
 Frame = -3

Query: 24   KILIIGNSSVGKTSFLFRYADDSFTPAFVSTVGIDFKVKTIYRNDKRIKLQIWDTAGQER 83
            K+ ++G+S VGK+S + R+   S+ P+  ST+G  F  K++  +    + QIWDTAGQE+
Sbjct: 1065 KVCLLGDSGVGKSSIVLRFVTGSYRPSQESTIGASFMSKSLVVDGAGYRFQIWDTAGQEK 886

Query: 84   YRTITTAYYRGAMGFILMYDITNEESFNAVQDWSTQIKTYSWDNAQVLLVGNKCDMEDER 143
            +R +   YYRGA   +++YD+T   +F +V+ W  +++++   N  + + GNKCD+E+ R
Sbjct: 885  FRALAPMYYRGAAAAVIVYDVTRPRTFKSVKSWIQELRSFGPPNIVLAIAGNKCDLEELR 706

Query: 144  VVSSERGRQLADHLGFEFFEASAKDNINVKQTFERL 179
             V  +  ++ A  +   F E SA   +NV++ F  L
Sbjct: 705  EVVEKDAQEYASSISAIFGETSAMTAVNVEEMFTEL 598
>34468
          Length = 1502

 Score =  112 bits (280), Expect = 1e-25,   Method: Compositional matrix adjust.
 Identities = 60/181 (33%), Positives = 98/181 (54%), Gaps = 2/181 (1%)
 Frame = +1

Query: 22  MFKILIIGNSSVGKTSFLFRYADDSFTPAFVSTVGIDFKVKTIYRNDKRIKLQIWDTAGQ 81
           +FKI++IG+S+VGKT   +R+    F     +T+G+DF+ K+I  + + +KLQ+WDTAGQ
Sbjct: 493 IFKIIVIGDSNVGKTCLTYRFCLGKFPDKTEATIGVDFREKSIQVDSEHLKLQLWDTAGQ 672

Query: 82  ERYR-TITTAYYRGAMGFILMYDITNEESFNAVQDWSTQIKTYSWDN-AQVLLVGNKCDM 139
           ER+R ++   YYR     + +YD+T   SF  +  W  +   ++       +LVGNKCD+
Sbjct: 673 ERFRKSMVQHYYRNVHAVVFVYDMTKMSSFENMPAWIEECDRHNLTKYIPRILVGNKCDV 852

Query: 140 EDERVVSSERGRQLADHLGFEFFEASAKDNINVKQTFERLVDVICEKMSESLDTADPAVT 199
            +   V++   ++ AD      FE SAKD+          VD I   ++  L  + P + 
Sbjct: 853 VERIAVNTNLAQKFADAHNMPLFETSAKDDEKANH-----VDAIFMTVAHKLKXSKPMMP 1017

Query: 200 G 200
            
Sbjct: 1018A 1020
>05468
          Length = 1558

 Score =  112 bits (280), Expect = 1e-25,   Method: Compositional matrix adjust.
 Identities = 63/174 (36%), Positives = 103/174 (59%), Gaps = 7/174 (4%)
 Frame = -3

Query: 20   DYMFKILIIGNSSVGKTSFLFRYADDSFTPAFVSTVGIDFKVKTI-YRNDKRIKLQIWDT 78
            ++++KIL+IG    GKTS + RY    F+  + +T+G+DF +K + +  D  I+LQ+WD 
Sbjct: 1547 EHLYKILVIGELGTGKTSIIKRYVHQFFSQHYRATIGVDFALKVLNWDADTLIRLQLWDI 1368

Query: 79   AGQERYRTITTAYYRGAMGFILMYDITNEESFNAVQDWSTQI--KTYSWDNAQV--LLVG 134
            AGQER+  +T  YY+ A+G  +++D+T   +F+AV  W   +  K    D + V  +L+ 
Sbjct: 1367 AGQERFGNMTRVYYKEAVGAFVVFDVTRASTFDAVTKWKNDLDSKVQLADGSPVPCVLLA 1188

Query: 135  NKCDMEDERVV-SSERGRQLADHLGF-EFFEASAKDNINVKQTFERLVDVICEK 186
            NKCD   E +V ++ +  +     GF  ++E SAK+NIN+ +    LV  I EK
Sbjct: 1187 NKCDQAKEGLVNNTSQMDEFCSEKGFIGWYETSAKENINIDEAARFLVTRILEK 1026
>26083
          Length = 432

 Score =  108 bits (270), Expect = 2e-24,   Method: Compositional matrix adjust.
 Identities = 50/114 (43%), Positives = 76/114 (66%)
 Frame = +1

Query: 23  FKILIIGNSSVGKTSFLFRYADDSFTPAFVSTVGIDFKVKTIYRNDKRIKLQIWDTAGQE 82
           FK++ +G  SVGKTS + R+  DSF   + +T+GIDF  KT+Y  D+ I+LQ+WDTAGQE
Sbjct: 79  FKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTIRLQLWDTAGQE 258

Query: 83  RYRTITTAYYRGAMGFILMYDITNEESFNAVQDWSTQIKTYSWDNAQVLLVGNK 136
           R+R++  +Y R +   +++YDITN  SF+    W   ++T    +  ++LVGNK
Sbjct: 259 RFRSLIPSYIRDSSVAVVVYDITNANSFHQTSKWIDDVRTERGSDVIIMLVGNK 420
>33374
          Length = 489

 Score = 95.9 bits (237), Expect(2) = 2e-24,   Method: Compositional matrix adjust.
 Identities = 44/114 (38%), Positives = 69/114 (60%)
 Frame = +1

Query: 59  FKVKTIYRNDKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEESFNAVQDWST 118
           F  +T+  +D  +K +IWDTAGQERY ++   YYRGA   I++YDITN+++F   + W  
Sbjct: 139 FLTQTVCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNQDTFGRAKTWVK 318

Query: 119 QIKTYSWDNAQVLLVGNKCDMEDERVVSSERGRQLADHLGFEFFEASAKDNINV 172
           +++  +  N  + L GNK D+ ++R+V  E  +  A+     F E SAK  +NV
Sbjct: 319 ELQRQASPNIVIALAGNKADLANKRMVEFEEAQAYAEENSLLFMETSAKTAMNV 480

 Score = 33.1 bits (74), Expect(2) = 2e-24,   Method: Compositional matrix adjust.
 Identities = 14/37 (37%), Positives = 23/37 (62%)
 Frame = +2

Query: 23 FKILIIGNSSVGKTSFLFRYADDSFTPAFVSTVGIDF 59
          FK++++G S+VGK+S + R+    F     ST+G  F
Sbjct: 32 FKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAF 142
>07465
          Length = 1103

 Score =  106 bits (264), Expect = 9e-24,   Method: Compositional matrix adjust.
 Identities = 58/180 (32%), Positives = 93/180 (51%)
 Frame = +3

Query: 36  TSFLFRYADDSFTPAFVSTVGIDFKVKTIYRNDKRIKLQIWDTAGQERYRTITTAYYRGA 95
           +S + RY    FT  +  T+G+DF  + I    + ++L +WDTAGQE +  IT AYYRGA
Sbjct: 240 SSMIQRYCKGIFTKDYKKTIGVDFLERQIEVGGEDVRLMLWDTAGQEEFDAITKAYYRGA 419

Query: 96  MGFILMYDITNEESFNAVQDWSTQIKTYSWDNAQVLLVGNKCDMEDERVVSSERGRQLAD 155
              +L +   + +SF A++ W  +++    +   V +V NK D+ D+ VV  E    LA 
Sbjct: 420 QACVLAFSTVDRDSFEALETWKRKVEDEVGEIGMV-IVQNKIDLIDDAVVRPEEAENLAK 596

Query: 156 HLGFEFFEASAKDNINVKQTFERLVDVICEKMSESLDTADPAVTGAKQGPQLTDQQAPPH 215
            L   F+  S K+N+NV + F  L D    +++  +D  +  +T  K G  L   +   H
Sbjct: 597 KLRLRFYRTSVKENMNVDEVFRYLADKYLHQLNTGMDEVN--LTPQKIGQGLIQTETKNH 770
>17511
          Length = 483

 Score = 96.3 bits (238), Expect = 8e-21,   Method: Compositional matrix adjust.
 Identities = 43/122 (35%), Positives = 77/122 (63%), Gaps = 4/122 (3%)
 Frame = -3

Query: 22  MFKILIIGNSSVGKTSFLFRYADDSFTPAFVSTVGIDFKVKTIYRNDKRIKLQIWDTAGQ 81
           + K++I+G+S VGKTS + +Y +  F+  + +T+G DF  K +  +D+ + +QIWDTAGQ
Sbjct: 367 LLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQIWDTAGQ 188

Query: 82  ERYRTITTAYYRGAMGFILMYDITNEESFNAVQDWS----TQIKTYSWDNAQVLLVGNKC 137
           ER++++  A+YRGA   +L++D+T   +F ++  W      Q      +N   +++GNK 
Sbjct: 187 ERFQSLGVAFYRGADCCVLVFDVTMPNTFRSLDSWRDEFLIQASPRDPENFPFVVIGNKI 8

Query: 138 DM 139
           D+
Sbjct: 7   DL 2
>07580
          Length = 921

 Score = 95.5 bits (236), Expect = 2e-20,   Method: Compositional matrix adjust.
 Identities = 52/129 (40%), Positives = 75/129 (58%), Gaps = 1/129 (0%)
 Frame = +3

Query: 62  KTIYRNDKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEESFNAVQDWSTQI- 120
           K +  + ++  L+I DTAG E++  +   Y +   GF+L Y IT + +FN +Q+   QI 
Sbjct: 177 KQVEVDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFLLAYSITAQSTFNDLQELREQIL 356

Query: 121 KTYSWDNAQVLLVGNKCDMEDERVVSSERGRQLADHLGFEFFEASAKDNINVKQTFERLV 180
           +    D+  +LLVGNKCD+EDERVV  ++G+ LA      F E SAK  INV + F  LV
Sbjct: 357 RVKDTDDVPMLLVGNKCDLEDERVVGKDQGQGLARSFSCAFLETSAKARINVNEIFMDLV 536

Query: 181 DVICEKMSE 189
             I +K  E
Sbjct: 537 RQINKKSPE 563
>13901
          Length = 962

 Score = 94.7 bits (234), Expect = 2e-20,   Method: Compositional matrix adjust.
 Identities = 44/96 (45%), Positives = 67/96 (69%), Gaps = 1/96 (1%)
 Frame = -3

Query: 22  MFKILIIGNSSVGKTSFLFRYADDSFTPAFVSTVGIDFKVKTIYRNDK-RIKLQIWDTAG 80
           +FK++IIG+ +VGKTSF+ RY +DSF   +  T+G+DF +K I  +DK  IKLQ+WD AG
Sbjct: 288 LFKVIIIGDPTVGKTSFVQRYVNDSFRRDYKMTIGVDFALKVIRWSDKCNIKLQLWDIAG 109

Query: 81  QERYRTITTAYYRGAMGFILMYDITNEESFNAVQDW 116
           QER+ ++T  YY+ A   I+M+D+T + ++     W
Sbjct: 108 QERFTSMTRVYYKDAHACIVMFDLTQKNTYQNAIRW 1
>33794
          Length = 779

 Score = 90.5 bits (223), Expect = 4e-19,   Method: Compositional matrix adjust.
 Identities = 46/123 (37%), Positives = 74/123 (60%)
 Frame = -1

Query: 57  IDFKVKTIYRNDKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEESFNAVQDW 116
           + +K  TI    KR+KLQIWDT+GQ R+ TI  +Y RGA G IL+YDITN+ SF+ +  W
Sbjct: 692 VAYKTTTILLEGKRVKLQIWDTSGQGRFCTIIRSYSRGAQGIILVYDITNKWSFDGIDRW 513

Query: 117 STQIKTYSWDNAQVLLVGNKCDMEDERVVSSERGRQLADHLGFEFFEASAKDNINVKQTF 176
             +++ ++    +V LVGN+  +  +R V++++    A       FE S   + N++++F
Sbjct: 512 LKEVEEHAPGIPKV-LVGNRLHLAYKRQVAAKQAETYASRNNMSCFEISPLCDFNIRESF 336

Query: 177 ERL 179
             L
Sbjct: 335 CEL 327
>01398
          Length = 1421

 Score = 88.6 bits (218), Expect = 2e-18,   Method: Compositional matrix adjust.
 Identities = 46/144 (31%), Positives = 77/144 (53%), Gaps = 4/144 (2%)
 Frame = -2

Query: 81   QERYRTITTAYYRGAMGFILMYDITNEESFNAVQDWSTQIKTYSWDNAQVLLV-GNKCDM 139
            QER+R+IT +YYR ++G I++YDIT   +F  ++ W  + + +   +  + LV G+K D 
Sbjct: 1420 QERFRSITRSYYRNSVGVIIVYDITKRSTFENLKQWYEEARNHIEPHKAIFLVLGHKSDR 1241

Query: 140  EDERVVSSERGRQLADHLGFEFFEASAKDNINVKQTFERLVDVICEKMSESLDTADPAVT 199
            ED R V++  GR+ A+  G +FFE SAK   N++  F ++     + + +     +    
Sbjct: 1240 EDARQVTAREGRRFAEMHGLKFFETSAKSGHNIEDVFAQIAKDTYQHLQDGHIRLEEGWD 1061

Query: 200  GAKQG---PQLTDQQAPPHQDCAC 220
            G KQG   P+ T   A   +   C
Sbjct: 1060 GVKQGFARPRETVHLAEGEESGGC 989
>14456
          Length = 1867

 Score = 88.2 bits (217), Expect = 3e-18,   Method: Compositional matrix adjust.
 Identities = 48/153 (31%), Positives = 83/153 (54%), Gaps = 4/153 (2%)
 Frame = -1

Query: 28   IGNSSVGKTSFLFRYADDSFTPAFVSTVGIDFKVKTIYRNDKRIKLQIWDTAGQERYRTI 87
            +    VGK+S + R+  + F      T+G++F  K +  +D+   +QIWDTAGQER++++
Sbjct: 1123 LKQGGVGKSSLMNRFVSNKFDAQSFHTIGVEFLNKDVVVDDETYTMQIWDTAGQERFKSL 944

Query: 88   TTAYYRGAMGFILMYDITNEESFNAVQDWSTQIKTYSWDNAQV----LLVGNKCDMEDER 143
             T +YRGA   +L + + + +SF  +  W  +   Y+     V    +++GNK D+E  +
Sbjct: 943  RTPFYRGADCCLLTFSVDSMQSFRNLSMWRKEFLYYADIQDGVTFPFVVLGNKIDVEGRQ 764

Query: 144  VVSSERGRQLADHLGFEFFEASAKDNINVKQTF 176
            V + E       +    +FE SAKD  NV++ F
Sbjct: 763  VTNEEARSWCTANSNAPYFETSAKDATNVEKAF 665
>13750
          Length = 503

 Score = 85.9 bits (211), Expect = 1e-17,   Method: Compositional matrix adjust.
 Identities = 51/151 (33%), Positives = 79/151 (52%), Gaps = 2/151 (1%)
 Frame = -2

Query: 35  KTSFLFRYADDSFTPAFVSTVGIDFKVKTIYRNDK-RIKLQIWDTAGQERYRTITTAYYR 93
           KT  L RY    F    + T+ +        R D   ++  +WDT G E YR++  +++R
Sbjct: 502 KTCLLRRYQKGFFMDRTMPTIAVLCSEFNESRTDPLNVRYTLWDTGGAETYRSLWVSHFR 323

Query: 94  GAMGFILMYDITNEESF-NAVQDWSTQIKTYSWDNAQVLLVGNKCDMEDERVVSSERGRQ 152
           GA   +L+YD+T E SF  A   W   +   +   AQV+ VG+K D+E+ RV+S+ERG+ 
Sbjct: 322 GAQVALLVYDVTCEWSFLTATTVWRKALMK-NIPEAQVIFVGSKTDLEENRVISTERGQA 146

Query: 153 LADHLGFEFFEASAKDNINVKQTFERLVDVI 183
            A   G+ FFE S+    NV   F  +  ++
Sbjct: 145 FATQCGYTFFETSSVTGKNVDAVFWEIAFIL 53
>11257
          Length = 1102

 Score = 84.3 bits (207), Expect = 3e-17,   Method: Compositional matrix adjust.
 Identities = 46/124 (37%), Positives = 73/124 (58%), Gaps = 4/124 (3%)
 Frame = -2

Query: 73   LQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEESFNAVQDWSTQIKTYS--WDNAQ- 129
            +QIWDTAGQERY+++ T +YRG    +L + + N +S  ++ DW  +   Y+   D+A  
Sbjct: 1020 MQIWDTAGQERYKSLRTPFYRGTDCCLLTFSVDNLKSLQSLSDWYDEFVNYADIQDSASF 841

Query: 130  -VLLVGNKCDMEDERVVSSERGRQLADHLGFEFFEASAKDNINVKQTFERLVDVICEKMS 188
              +++GNK D+E+  V S +       H    +FE SAKD++NV+Q F  +V  + E M 
Sbjct: 840  PFVIIGNKADIEEREVSSEDAYNWCRTHGNLPYFETSAKDSLNVQQAFLAVVRRLRE-MD 664

Query: 189  ESLD 192
            E +D
Sbjct: 663  EQMD 652
>30760
          Length = 596

 Score = 81.6 bits (200), Expect = 2e-16,   Method: Compositional matrix adjust.
 Identities = 49/158 (31%), Positives = 85/158 (53%), Gaps = 5/158 (3%)
 Frame = -1

Query: 24  KILIIGNSSVGKTSFLFRYADDS--FTPAFVSTVGIDFKVKTIYRNDKR--IKLQIWDTA 79
           K ++ G+S VGK+S    +  DS  F   +  T G++  VK +   D R  ++L ++D+A
Sbjct: 524 KCIVTGDSGVGKSSICQVFHSDSAHFPKNYSMTTGVEVLVKLVNIPDSRDQVELYLFDSA 345

Query: 80  GQERYRTITTAYYRGAMGFILMYDITNEESFNAVQDWSTQIKTYSWDNA-QVLLVGNKCD 138
           G+E +    T ++      +++YD+T+E SF+    W  +++    +     +LV NK D
Sbjct: 344 GKEIFSENVTKFWDQPSVVMVVYDVTDETSFSGCVRWLERVRAAKPNTVIPGVLVANKTD 165

Query: 139 MEDERVVSSERGRQLADHLGFEFFEASAKDNINVKQTF 176
           +++ R VS + G+ LA   G E+FE SAK+  N    F
Sbjct: 164 LDERRRVSRKEGKDLAQSHGLEYFECSAKEMQNTDTPF 51
>26536
          Length = 829

 Score = 81.3 bits (199), Expect = 3e-16,   Method: Compositional matrix adjust.
 Identities = 45/119 (37%), Positives = 67/119 (56%), Gaps = 3/119 (2%)
 Frame = +2

Query: 68  DKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEESFN---AVQDWSTQIKTYS 124
           ++R+     DTAGQE Y ++   Y R   GFI++Y +T+  SF    AV  W T+ +  +
Sbjct: 119 ERRVSWTFLDTAGQEEYSSMREHYTRSGDGFIVVYSVTDVTSFQEAEAVFRWLTRFQDET 298

Query: 125 WDNAQVLLVGNKCDMEDERVVSSERGRQLADHLGFEFFEASAKDNINVKQTFERLVDVI 183
             +   +L GNK D+  +R V+ E GR++AD LG  +FE SAK   NV Q +  L+  I
Sbjct: 299 --SIHAVLCGNKTDLTSDRKVTPEEGRKMADRLGMLYFETSAKTGDNVSQVYHGLLRSI 469

 Score = 30.4 bits (67), Expect = 0.52,   Method: Compositional matrix adjust.
 Identities = 11/33 (33%), Positives = 21/33 (63%)
 Frame = +2

Query: 23  FKILIIGNSSVGKTSFLFRYADDSFTPAFVSTV 55
           +KI+++G+  VGK+S   R+  D+F   +  T+
Sbjct: 488 YKIVMLGSGGVGKSSLTIRFTQDTFLDVYDPTI 586
>32723
          Length = 384

 Score = 80.9 bits (198), Expect = 4e-16,   Method: Compositional matrix adjust.
 Identities = 36/96 (37%), Positives = 59/96 (61%)
 Frame = +2

Query: 81  QERYRTITTAYYRGAMGFILMYDITNEESFNAVQDWSTQIKTYSWDNAQVLLVGNKCDME 140
           QER+R+IT +YYR A   IL+YD+ +++S+ ++  W  +I+ Y+       LVGNK D  
Sbjct: 2   QERFRSITQSYYRSANALILVYDVCSQQSYESLPQWIHEIELYAGTKVLAFLVGNKIDQT 181

Query: 141 DERVVSSERGRQLADHLGFEFFEASAKDNINVKQTF 176
           D+R + +  G++ A+     F E SAK+  NV++ F
Sbjct: 182 DKREIPTHIGKEFAERYEMRFLETSAKEADNVEKLF 289
>01972
          Length = 2359

 Score = 69.3 bits (168), Expect(2) = 2e-15,   Method: Compositional matrix adjust.
 Identities = 33/128 (25%), Positives = 70/128 (54%), Gaps = 2/128 (1%)
 Frame = +3

Query: 51  FVSTVGIDFKVKTIYRNDKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEESF 110
           +V+T+G++      + +  ++K  +WDTAGQE++  +   YY      ++M+D+T+  ++
Sbjct: 387 YVATLGVEVHPLLFHTSRGKLKFNVWDTAGQEKFGGLRDGYYIQGQCAVIMFDVTSRVTY 566

Query: 111 NAVQDWSTQIKTYSWDNAQVLLVGNKCDMEDERVVSSERGRQLADHL--GFEFFEASAKD 168
             V +W   +     +N  ++L GNK D++D +V    + + +  H     ++++ SAK 
Sbjct: 567 KNVPNWHRDLVRVC-ENIPIVLCGNKVDIKDRKV----KAKAIVFHRKKNLQYYDISAKS 731

Query: 169 NINVKQTF 176
           N N ++ F
Sbjct: 732 NYNFEKPF 755

 Score = 29.6 bits (65), Expect(2) = 2e-15,   Method: Compositional matrix adjust.
 Identities = 10/25 (40%), Positives = 18/25 (72%)
 Frame = +1

Query: 23  FKILIIGNSSVGKTSFLFRYADDSF 47
           FK++++G+  VGKT+F+ R+    F
Sbjct: 304 FKLVLVGDGGVGKTTFVKRHVTGEF 378
>34597
          Length = 773

 Score = 70.1 bits (170), Expect(2) = 4e-14,   Method: Compositional matrix adjust.
 Identities = 36/110 (32%), Positives = 57/110 (51%)
 Frame = -2

Query: 109 SFNAVQDWSTQIKTYSWDNAQVLLVGNKCDMEDERVVSSERGRQLADHLGFEFFEASAKD 168
           SF  +  W   I  ++ ++ + +++GNKCDM D+RVVS ERG  +A      F E SAK 
Sbjct: 709 SFENIVKWLRNIDEHANEDVEKMILGNKCDMTDKRVVSKERGEAIAREHSIRFMETSAKS 530

Query: 169 NINVKQTFERLVDVICEKMSESLDTADPAVTGAKQGPQLTDQQAPPHQDC 218
           NIN+++ F  L + I +K +      +P      +G      +AP +  C
Sbjct: 529 NINIERAFCELAEAILDKTAGRESAENPERVVIDRG---NSDKAPGYNKC 389

 Score = 24.3 bits (51), Expect(2) = 4e-14,   Method: Compositional matrix adjust.
 Identities = 9/13 (69%), Positives = 12/13 (92%)
 Frame = -3

Query: 89  TAYYRGAMGFILM 101
           T+YYRGAMG +L+
Sbjct: 771 TSYYRGAMGIMLV 733
>12339
          Length = 578

 Score = 72.0 bits (175), Expect = 2e-13,   Method: Compositional matrix adjust.
 Identities = 45/145 (31%), Positives = 80/145 (55%), Gaps = 5/145 (3%)
 Frame = -2

Query: 81  QERYRTITTAYYRGAMGFILMYDITNEESFNAVQDWS----TQIKTYSWDNAQVLLVGNK 136
           QER++++  A+YRGA   IL+YD+T  ++F+++  W      Q      ++   +++GNK
Sbjct: 577 QERFQSLGVAFYRGADCCILVYDVTEXKTFDSLDSWQREFLNQASPRDPEHFPFVVIGNK 398

Query: 137 CDMEDERVVSSERGRQ-LADHLGFEFFEASAKDNINVKQTFERLVDVICEKMSESLDTAD 195
            D+ D RVV+++RG+   +   G  +FE SAK+ INV+Q F+ +      + SE      
Sbjct: 397 IDL-DNRVVTAKRGQGWCSTKGGIPYFETSAKEAINVEQAFQTVAKNALAQESEVEIDDF 221

Query: 196 PAVTGAKQGPQLTDQQAPPHQDCAC 220
           P+        +L++  + P + CAC
Sbjct: 220 PSEI------RLSNDDSRPRERCAC 164
>19006
          Length = 568

 Score = 70.1 bits (170), Expect = 6e-13,   Method: Compositional matrix adjust.
 Identities = 36/120 (30%), Positives = 68/120 (56%), Gaps = 1/120 (0%)
 Frame = -2

Query: 24  KILIIGNSSVGKTSFLFRYADDSFTPAFVSTVGIDFKVKTIYRNDKRIKLQIWDTAGQER 83
           K++I+G+ + GKT  L  ++ D F   +V TV  ++ V  I  + K+++L +WDTAGQE 
Sbjct: 432 KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENY-VADIEVDSKQVELALWDTAGQED 256

Query: 84  YRTITTAYYRGAMGFILMYDITNEESF-NAVQDWSTQIKTYSWDNAQVLLVGNKCDMEDE 142
           Y  +    Y      ++ + I + +S  N  + W+ +++ +   N  ++LVGNK D+ ++
Sbjct: 255 YDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVRHFC-PNVPIILVGNKKDLRND 79
>11728
          Length = 635

 Score = 69.3 bits (168), Expect = 1e-12,   Method: Compositional matrix adjust.
 Identities = 39/134 (29%), Positives = 70/134 (52%), Gaps = 2/134 (1%)
 Frame = -1

Query: 23  FKILIIGNSSVGKTSFLFRYADDSFTPAFVSTVGIDFKVKTIYRNDKRIKLQIWDTAGQE 82
            K +++G+ +VGKT  L  Y  ++F   ++ TV  D     +  + K I L +WDTAGQE
Sbjct: 488 IKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTV-FDNYSANVMVDSKPINLGLWDTAGQE 312

Query: 83  RYRTITTAYYRGAMGFILMYDITNEESFNAVQ-DWSTQIKTYSWDNAQVLLVGNKCDM-E 140
            Y  +    Y     F++ + + +  SF  V+  W  ++ ++   N  ++LVG K D+ E
Sbjct: 311 DYDRLRPLSYPQTDVFLICFSLISPASFENVKAKWYPEV-SHHCPNTPIILVGTKLDLRE 135

Query: 141 DERVVSSERGRQLA 154
           D+  +   + ++LA
Sbjct: 134 DKETIEKLKEKKLA 93
>35581
          Length = 364

 Score = 63.2 bits (152), Expect = 7e-11,   Method: Compositional matrix adjust.
 Identities = 32/96 (33%), Positives = 56/96 (58%), Gaps = 1/96 (1%)
 Frame = +2

Query: 23  FKILIIGNSSVGKTSFLFRYADDSFTPAFVSTVGIDFKVKTIYRNDKRI-KLQIWDTAGQ 81
           FK +++G++ VGKT  L R A D F  + ++++     + T+      +  + +WDTAGQ
Sbjct: 47  FKCVLLGDAGVGKTCLLNRLATDKFLDSPLTSLTTASLLTTVTLTSGVMASVDLWDTAGQ 226

Query: 82  ERYRTITTAYYRGAMGFILMYDITNEESFNAVQDWS 117
           ERYR++T++YYR     +++YD    E    + DW+
Sbjct: 227 ERYRSLTSSYYRDTKAVLIVYD---AEHKLKLTDWT 325
>19046
          Length = 445

 Score = 62.8 bits (151), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 37/105 (35%), Positives = 58/105 (55%), Gaps = 2/105 (1%)
 Frame = -2

Query: 81  QERYRTITTAYYRGAMGFILMYDITNEESFNAVQDWSTQI-KTYSWDNAQVLLVGNKCDM 139
           QE +  +   Y R   GF+L++ +T+  SF  + ++ TQI +    D+  ++L  NK D+
Sbjct: 444 QEEFSAMREQYMRKGDGFLLVFSVTDFRSFENMANFHTQILRVKDRDSYPMILCANKVDL 265

Query: 140 EDERVVSSERGRQLADHLGFEFFEASAKD-NINVKQTFERLVDVI 183
             +R VS E+ R LA  L   + E SAKD  +NV   F ++V VI
Sbjct: 264 VHQRKVSEEQVRDLATRLRIPYIETSAKDPPLNVDLAFHQVVRVI 130
>24619
          Length = 509

 Score = 61.2 bits (147), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 36/105 (34%), Positives = 57/105 (54%), Gaps = 2/105 (1%)
 Frame = -2

Query: 81  QERYRTITTAYYRGAMGFILMYDITNEESFNAVQDWSTQI-KTYSWDNAQVLLVGNKCDM 139
           QE +  +   Y R   GF+L++ + + +SF  + ++ TQI +    D   ++L  NK D+
Sbjct: 508 QEEFSAMREQYMRKGDGFLLVFSVIDYQSFENMVNFHTQILRVKDRDTYPMILCANKVDL 329

Query: 140 EDERVVSSERGRQLADHLGFEFFEASAKD-NINVKQTFERLVDVI 183
             +R VS E+ R LA  L   + E SAKD  +NV   F ++V VI
Sbjct: 328 VHQRKVSEEQVRDLATRLRIPYIETSAKDPPLNVDLAFHQVVRVI 194
>13745
          Length = 1045

 Score = 61.2 bits (147), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 36/115 (31%), Positives = 62/115 (53%), Gaps = 5/115 (4%)
 Frame = +2

Query: 81  QERYRTITTAYYRGAMGFILMYDITNEESFNAVQDWS----TQIKTYSWDNAQVLLVGNK 136
           QER++++  A+YRGA   +L+YD+T   SF  +  W      Q      ++   +++GNK
Sbjct: 2   QERFQSLGVAFYRGADCCVLVYDVTAPNSFKNLDSWRDEFLIQASPRDPEHFPFVVLGNK 181

Query: 137 CDMEDERVVSSERGRQLADHLG-FEFFEASAKDNINVKQTFERLVDVICEKMSES 190
            D+ D R VS+ R +Q         ++E SAK+ INV+  F+ +     E+ +E+
Sbjct: 182 VDL-DNRQVSTRRAQQWCQSKNDIPYYETSAKEGINVEMAFQTIAKNALEQETEA 343
>34359
          Length = 1042

 Score = 60.8 bits (146), Expect = 4e-10,   Method: Compositional matrix adjust.
 Identities = 31/122 (25%), Positives = 64/122 (52%)
 Frame = +3

Query: 23  FKILIIGNSSVGKTSFLFRYADDSFTPAFVSTVGIDFKVKTIYRNDKRIKLQIWDTAGQE 82
           FK++++G       + + R+   S    +V+T+G++        +   ++  +WDTAGQE
Sbjct: 54  FKLVLVGGRWEWANNIVKRHVTGS*K-KYVATLGVEVHPLQFNTSRGLLRFNVWDTAGQE 230

Query: 83  RYRTITTAYYRGAMGFILMYDITNEESFNAVQDWSTQIKTYSWDNAQVLLVGNKCDMEDE 142
           ++  +   YY      I+M+D+T+  ++  V +W   +     +N  ++L GNK D++D 
Sbjct: 231 KFGGLRDGYYIQGTCAIIMFDVTSRVTYKNVPNWHRDLVRVC-ENIPIVLCGNKVDIKDR 407

Query: 143 RV 144
           +V
Sbjct: 408 KV 413
>27191
          Length = 443

 Score = 58.2 bits (139), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 25/102 (24%), Positives = 51/102 (50%)
 Frame = +1

Query: 35  KTSFLFRYADDSFTPAFVSTVGIDFKVKTIYRNDKRIKLQIWDTAGQERYRTITTAYYRG 94
           KT  +  + +  F   +  TVG+D+  K    N   +++ +WD +G   Y  +    Y G
Sbjct: 1   KTCLIKHFCESKFNQGYQPTVGVDYGFKIQTVNGVDMRVHMWDLSGSNEYLDVRNELYTG 180

Query: 95  AMGFILMYDITNEESFNAVQDWSTQIKTYSWDNAQVLLVGNK 136
           +    +++D++N  SF A+  W  +I  ++  +   ++VGN+
Sbjct: 181 SDAIFIVFDVSNTPSFEALDSWLREINRFATGSPLNVIVGNR 306
>31291
          Length = 446

 Score = 57.0 bits (136), Expect = 5e-09,   Method: Compositional matrix adjust.
 Identities = 39/124 (31%), Positives = 60/124 (48%), Gaps = 14/124 (11%)
 Frame = -1

Query: 73  LQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEESFNAVQ-DWSTQIKTYSWDNAQVL 131
           LQ+WDTAGQE Y  +    Y     F+L + + +E S   V+  W  +I+ +   +  ++
Sbjct: 446 LQLWDTAGQEDYDRLRPLAYPNTDVFMLXFSLMSEASMKNVKVKWYPEIRHHD-PHVPIV 270

Query: 132 LVGNKCDMEDER------------VVSSERGRQLADHL-GFEFFEASAKDNINVKQTFER 178
           LVG K D+  ++             VSS +G  LA  +    +FE S+K   N+K  FE 
Sbjct: 269 LVGTKLDLRQDKEAVRKLRSSRQDPVSSNQGNDLAKAIKAKRYFECSSKTQENLKTAFEE 90

Query: 179 LVDV 182
            V V
Sbjct: 89  TVRV 78
>00858
          Length = 1658

 Score = 55.5 bits (132), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 36/109 (33%), Positives = 52/109 (47%), Gaps = 1/109 (0%)
 Frame = -2

Query: 73   LQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEESFNAVQDWSTQIKTYS-WDNAQVL 131
            L I DTAGQE    +     R   GF+ ++ + N +SF  +  +  QIK     D   ++
Sbjct: 1441 LDILDTAGQEEXSAMRDQCMRTGEGFLCVFAVXNLKSFEDINQYREQIKRVKDADEVPMV 1262

Query: 132  LVGNKCDMEDERVVSSERGRQLADHLGFEFFEASAKDNINVKQTFERLV 180
            LVGNK D+   R V   +G+ +A+     + E SAK    V   F  LV
Sbjct: 1261 LVGNKVDLPI-RNVEQRQGKHMAELYHIPYVETSAKTRQGVDDAFYTLV 1118
>19656
          Length = 428

 Score = 54.3 bits (129), Expect = 4e-08,   Method: Compositional matrix adjust.
 Identities = 27/102 (26%), Positives = 51/102 (50%), Gaps = 1/102 (0%)
 Frame = +3

Query: 23  FKILIIGNSSVGKTSFLFRYADDSFTPAFVSTVGIDFKVKTIYRNDKRIKLQIWDTAGQE 82
            K +++G+ +VGKT  L  Y  ++F   ++ TV  D     +  + + + L +WDTAGQE
Sbjct: 114 IKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTV-FDNYSANVMVDGRPVNLGLWDTAGQE 290

Query: 83  RYRTITTAYYRGAMGFILMYDITNEESFNAVQ-DWSTQIKTY 123
            Y  +    Y     F+L + + +  SF  ++  W  ++  +
Sbjct: 291 DYDRLRPLSYPQTDVFLLCFSVASPASFENIRAKWYPEVNHH 416
>01095
          Length = 1745

 Score = 53.5 bits (127), Expect = 6e-08,   Method: Compositional matrix adjust.
 Identities = 32/121 (26%), Positives = 61/121 (50%)
 Frame = -1

Query: 100  LMYDITNEESFNAVQDWSTQIKTYSWDNAQVLLVGNKCDMEDERVVSSERGRQLADHLGF 159
            ++YDITN+++F   + W  +++  +  N  + L GNK D+ ++R+V  E  +  A+    
Sbjct: 1745 VVYDITNQDTFGRAKTWVKELQRQASPNIVIALAGNKADLANKRMVEFEEAQAYAEENSL 1566

Query: 160  EFFEASAKDNINVKQTFERLVDVICEKMSESLDTADPAVTGAKQGPQLTDQQAPPHQDCA 219
             F E SAK  +NV   F  +   + +  +E    + P     +QG +L ++Q+   +   
Sbjct: 1565 LFMETSAKTAMNVNDIFLAIAKKLPK--NEGGGGSQP----RQQGVRLNNEQSQQSEGGC 1404

Query: 220  C 220
            C
Sbjct: 1403 C 1401
>09204
          Length = 1051

 Score = 53.1 bits (126), Expect = 9e-08,   Method: Compositional matrix adjust.
 Identities = 27/103 (26%), Positives = 55/103 (53%), Gaps = 4/103 (3%)
 Frame = -3

Query: 83   RYRTITTAYYRGAMGFILMYDITNEESFNAVQDWSTQIKTYSWDNAQVLLVGNKCDM--- 139
            RY  ++  YYRGA   IL +D+T++ SF+ ++ W  +++ +  +  ++ + G K D+   
Sbjct: 1049 RYEAMSRIYYRGAKAAILCFDLTDKSSFDRIRFWIGELRQHE-EECKLYICGTKFDLVHD 873

Query: 140  -EDERVVSSERGRQLADHLGFEFFEASAKDNINVKQTFERLVD 181
              + R V     + LAD    E +E S+    N+++ F ++ +
Sbjct: 872  DPERRAVPRSVAKALADDCMAEIYETSSMTGDNIEKLFTKIAE 744
>08153
          Length = 1703

 Score = 51.2 bits (121), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 39/153 (25%), Positives = 72/153 (47%), Gaps = 2/153 (1%)
 Frame = +1

Query: 9   YGQKESSDQNFDYMFKILIIGNSSVGKTSFLFRYADDSFTPAFVSTVGIDFKVKTI-YRN 67
           +G+KE          +IL++G  + GKT+ L++          + T+G  F V+T+ Y+N
Sbjct: 70  FGKKE---------VRILMVGLDAAGKTTILYKLKLGEIVTT-IPTIG--FNVETVEYKN 213

Query: 68  DKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEESFN-AVQDWSTQIKTYSWD 126
              I   +WD  GQ++ R +   Y++   G I + D  + E  N A ++ +  +      
Sbjct: 214 ---ISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERINEAKEELARMLNEDDLR 384

Query: 127 NAQVLLVGNKCDMEDERVVSSERGRQLADHLGF 159
           +A +L+  NK D+ +    S     ++  HLG 
Sbjct: 385 DAIILVFANKQDLPNAYSAS-----EVTAHLGL 468
>00552
          Length = 455

 Score = 49.7 bits (117), Expect = 9e-07,   Method: Compositional matrix adjust.
 Identities = 20/49 (40%), Positives = 31/49 (63%)
 Frame = -3

Query: 75  IWDTAGQERYRTITTAYYRGAMGFILMYDITNEESFNAVQDWSTQIKTY 123
           IWDTAGQERY+++ T +YRG    +L + + N +S  ++ DW  +   Y
Sbjct: 147 IWDTAGQERYKSLRTPFYRGTDCCLLTFSVDNLKSLQSLSDWYDEFVNY 1

 Score = 33.9 bits (76), Expect = 0.052,   Method: Compositional matrix adjust.
 Identities = 13/53 (24%), Positives = 30/53 (56%)
 Frame = -1

Query: 22  MFKILIIGNSSVGKTSFLFRYADDSFTPAFVSTVGIDFKVKTIYRNDKRIKLQ 74
           + K++++G+  VGK+S + R+  + F      T+G++F  K +  + +   +Q
Sbjct: 446 LLKVVLLGDGGVGKSSLMNRFVSNKFDAQSFHTIGVEFLTKDVVVDGETFTMQ 288
>09827
          Length = 1201

 Score = 47.4 bits (111), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 34/136 (25%), Positives = 67/136 (49%), Gaps = 2/136 (1%)
 Frame = -3

Query: 23   FKILIIGNSSVGKTSFLFRYADDSFTPAFVSTVGIDFKVKTI-YRNDKRIKLQIWDTAGQ 81
             +IL++G  + GKT+ L++          + T+G  F V+T+ Y+N   I   +WD  GQ
Sbjct: 1112 MRILMVGLDAAGKTTILYKLKLGEIVTT-IPTIG--FNVETVEYKN---ISFTVWDVGGQ 951

Query: 82   ERYRTITTAYYRGAMGFILMYDITNEESFN-AVQDWSTQIKTYSWDNAQVLLVGNKCDME 140
            ++ R +   Y++   G I + D  ++E    A ++ +  +      +A +L+  NK D+ 
Sbjct: 950  DKIRPLWRHYFQNTQGLIFVVDSNDKERVQEAREELTRMLNEDELRDAVLLVFANKQDLP 771

Query: 141  DERVVSSERGRQLADH 156
               + ++E   +L  H
Sbjct: 770  -HAMATAEITEKLGLH 726
>14775
          Length = 380

 Score = 45.1 bits (105), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 35/150 (23%), Positives = 55/150 (36%), Gaps = 1/150 (0%)
 Frame = -2

Query: 35  KTSFLFRYADDSFTPAFVSTVGIDFKVKTIYRNDK-RIKLQIWDTAGQERYRTITTAYYR 93
           KT  L RY    F    + T+ +        R D   ++  +WDT G E YR++  +++R
Sbjct: 379 KTCLLRRYQKGFFMDRTMPTIAVLCSEFNESRTDPLNVRYTLWDTGGAETYRSLWVSHFR 200

Query: 94  GAMGFILMYDITNEESFNAVQDWSTQIKTYSWDNAQVLLVGNKCDMEDERVVSSERGRQL 153
           GA   +L+YD+T                                          ERG+  
Sbjct: 199 GAQVALLVYDVT-----------------------------------------CERGQAF 143

Query: 154 ADHLGFEFFEASAKDNINVKQTFERLVDVI 183
           A   G+ FFE S+    NV   F  +  ++
Sbjct: 142 ATQCGYTFFETSSVTGKNVDAVFWEIAFIL 53
>29380
          Length = 853

 Score = 44.7 bits (104), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 24/89 (26%), Positives = 47/89 (52%), Gaps = 1/89 (1%)
 Frame = -2

Query: 99  ILMYDITNEESFNAVQDWSTQIKTYSWDNAQVLLVGNKCDMEDE-RVVSSERGRQLADHL 157
           I++YD+   ++F+    W  +++  + ++  ++L GNK D+  + R VS E  +  A   
Sbjct: 840 IIVYDVNIADTFSRALAWVKELRQQNTESVLIILAGNKVDLATQHRAVSFEDAQSFAREN 661

Query: 158 GFEFFEASAKDNINVKQTFERLVDVICEK 186
           G  F E SAK  + V + F  L + + ++
Sbjct: 660 GLLFAEVSAKTGMAVNEIFMTLANQLIQQ 574
>14119
          Length = 602

 Score = 41.6 bits (96), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 23/82 (28%), Positives = 40/82 (48%), Gaps = 1/82 (1%)
 Frame = +1

Query: 109 SFNAVQDWSTQIKTYSWDNAQVLLVGNKCDMEDE-RVVSSERGRQLADHLGFEFFEASAK 167
           +FN    W  +++  +  +  ++L GNK D+  E R VS++  R  A+  G  F E SAK
Sbjct: 1   TFNRALAWVKELRQQNAGSVLIVLAGNKADLASEHRAVSADDARTFAEDNGLIFAEVSAK 180

Query: 168 DNINVKQTFERLVDVICEKMSE 189
             + V + F  +   +  +  E
Sbjct: 181 TGMAVSEVFMTIAHKLVRRAEE 246
>10862
          Length = 2896

 Score = 39.3 bits (90), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 20/71 (28%), Positives = 34/71 (47%), Gaps = 1/71 (1%)
 Frame = -3

Query: 72   KLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEESFN-AVQDWSTQIKTYSWDNAQV 130
            +  +WD  GQ++ R +   YY G  G I + D  + +  + A Q+    I      +A +
Sbjct: 2483 QFNVWDVGGQDKIRPLWRHYYTGTQGLIFVVDCADRDRIDEARQELHRIINDREMRDAII 2304

Query: 131  LLVGNKCDMED 141
            L+  NK D+ D
Sbjct: 2303 LIFANKQDLPD 2271
>33605
          Length = 888

 Score = 37.4 bits (85), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 21/83 (25%), Positives = 41/83 (49%), Gaps = 3/83 (3%)
 Frame = +1

Query: 24  KILIIGNSSVGKTSFLFRYAD---DSFTPAFVSTVGIDFKVKTIYRNDKRIKLQIWDTAG 80
           ++L++G  + GKT+ L ++     D+ +P       + F +KT+    +  KL +WD  G
Sbjct: 502 RLLMLGLDNAGKTTILKKFNGEDIDTISPT------LGFNIKTL--EHRGFKLNVWDVGG 657

Query: 81  QERYRTITTAYYRGAMGFILMYD 103
           Q+  R+    Y+    G + + D
Sbjct: 658 QQSLRSYWRNYFESTDGLVWVVD 726
>25796
          Length = 422

 Score = 34.3 bits (77), Expect = 0.036,   Method: Compositional matrix adjust.
 Identities = 15/43 (34%), Positives = 27/43 (62%), Gaps = 2/43 (4%)
 Frame = -1

Query: 2   ASATDSRYGQKESSD--QNFDYMFKILIIGNSSVGKTSFLFRY 42
           AS T  +Y   ++++  + +DY+FK LIIG++  GK+  L  +
Sbjct: 134 ASTTKKQYNNAKTNNMSETYDYLFKFLIIGSAGSGKSCLLHHF 6
>06411
          Length = 1548

 Score = 31.2 bits (69), Expect = 0.38,   Method: Compositional matrix adjust.
 Identities = 21/57 (36%), Positives = 34/57 (59%), Gaps = 8/57 (14%)
 Frame = -2

Query: 30   NSSVGKT-SFLFRYADDSFTPAFVSTVGIDFK---VKTIYR----NDKRIKLQIWDT 78
            + ++GKT S++  +A DSFTPA V +   DF    +K I+R    ++K I L++  T
Sbjct: 1139 HKAMGKTKSYVLFHARDSFTPAIVGSSSPDFILVFLKLIHRA*TKSNKIISLELLPT 969
>10708
          Length = 2775

 Score = 31.2 bits (69), Expect = 0.38,   Method: Compositional matrix adjust.
 Identities = 12/45 (26%), Positives = 24/45 (53%)
 Frame = -2

Query: 69   KRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEESFNAV 113
            ++++L +WDTAGQE Y  +    Y      ++ + I + +S   +
Sbjct: 2729 QQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENI 2595
>06994
          Length = 429

 Score = 28.9 bits (63), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 11/34 (32%), Positives = 20/34 (58%)
 Frame = +1

Query: 82  ERYRTITTAYYRGAMGFILMYDITNEESFNAVQD 115
           E++  +   Y +   GF+L Y IT + +FN +Q+
Sbjct: 328 EQFTAMRDLYMKNGQGFLLAYSITAQSTFNDLQE 429
>18184
          Length = 558

 Score = 28.9 bits (63), Expect = 1.9,   Method: Compositional matrix adjust.
 Identities = 14/36 (38%), Positives = 19/36 (52%)
 Frame = -3

Query: 21  YMFKILIIGNSSVGKTSFLFRYADDSFTPAFVSTVG 56
           Y+F IL+ G    G    +  +  +SF   FVSTVG
Sbjct: 442 YLFYILLTGIVQFGYCCLVGTFPFNSFLAGFVSTVG 335
>31928
          Length = 429

 Score = 28.5 bits (62), Expect = 2.4,   Method: Compositional matrix adjust.
 Identities = 20/69 (28%), Positives = 32/69 (46%), Gaps = 4/69 (5%)
 Frame = +2

Query: 72  KLQIWDTAGQERYRT---ITTAYYRGAMGFILMYDITNEESFNAVQDWSTQI-KTYSWDN 127
           K++I+DT       T   +   Y     GF+L+YD T+ ESF  +      I K      
Sbjct: 107 KVRIFDTGAAALETTEGDLPKHYLNFPDGFVLVYDTTSWESFRRLDKLKKDIDKHRDKRE 286

Query: 128 AQVLLVGNK 136
             ++++GNK
Sbjct: 287 VHMIVIGNK 313
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|94401630|ref|XP_895540.2| PREDICTED: myeloid/lymphoid
or mixed lineage-leukemia translocation to 4 homolog isoform 1 [Mus
musculus]
         (1827 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

01067                                                                 174   3e-43
33766                                                                 100   2e-23
35518                                                                 107   4e-23
27345                                                                  66   1e-10
18965                                                                  58   3e-08
29705                                                                  50   7e-06
20073                                                                  46   2e-04
30101                                                                  37   0.051
37239                                                                  35   0.35 
10472                                                                  30   8.3  
08480                                                                  30   9.3  
>01067
          Length = 1298

 Score =  174 bits (441), Expect = 3e-43,   Method: Compositional matrix adjust.
 Identities = 84/130 (64%), Positives = 97/130 (74%), Gaps = 1/130 (0%)
 Frame = +2

Query: 5   GRDEERRKLADIIHHWNANRLDLFEISQPTEDLEFHGVMRFYFQDKAAGNFATKCIRVSS 64
            R  +R +L  +I  WN +  DLFE+S P +DLEFHGV+RFYFQ     N  TKCIRVSS
Sbjct: 827 ARQSDRERLTQVIQQWNIDHYDLFELSAPNQDLEFHGVVRFYFQGGNGANVITKCIRVSS 1006

Query: 65  TATTQDVIETLAEKFRPDMRMLSSPKYSLYEVHVSG-ERRLDIDEKPLVVQLNWNKDDRE 123
           TA T DVI+TL EKFRPDMRMLS  KY+LYEVHV+G ERRL   EK L VQLNW KD RE
Sbjct: 1007TAATSDVIDTLIEKFRPDMRMLSLNKYALYEVHVNGEERRLGDQEKLLWVQLNWGKDVRE 1186

Query: 124 GRFVLKNEND 133
           GRF+LK+EN+
Sbjct: 1187GRFLLKDENE 1216
>33766
          Length = 429

 Score = 99.8 bits (247), Expect(2) = 2e-23,   Method: Compositional matrix adjust.
 Identities = 45/88 (51%), Positives = 61/88 (69%)
 Frame = -2

Query: 901 IPTDLIENVVAVAENTADELARSDGRDVQLEEDPDLQLPFLLPEDGYSCDVVRNIPNGLQ 960
           +PT  I  VV +A +  DEL R++G +V+LEEDPDL LPFLLPEDGYSCD +R IP+GL 
Sbjct: 302 LPT-FIARVVDIAADMTDELTRTEGGEVRLEEDPDLHLPFLLPEDGYSCDTLRGIPDGLP 126

Query: 961 EFLDPLCQRGFCRLVPHTRSPGTWTIYF 988
           EF   L   G C +V ++ + G+W ++ 
Sbjct: 125 EFSSQLSSAGLCHMVANSLASGSWMVHM 42

 Score = 29.6 bits (65), Expect(2) = 2e-23,   Method: Compositional matrix adjust.
 Identities = 13/19 (68%), Positives = 15/19 (78%)
 Frame = -3

Query: 864 KYVPDDIPNINSTCFKLNS 882
           K   +DI NI+STCFKLNS
Sbjct: 415 KMTAEDINNISSTCFKLNS 359
>35518
          Length = 234

 Score =  107 bits (267), Expect = 4e-23,   Method: Composition-based stats.
 Identities = 48/65 (73%), Positives = 55/65 (84%)
 Frame = +2

Query: 35  EDLEFHGVMRFYFQDKAAGNFATKCIRVSSTATTQDVIETLAEKFRPDMRMLSSPKYSLY 94
           +DLEFHGV+RFYFQ     N  TKCIRVSSTATT+DVI+TL EKFRPDMRML+  KY+LY
Sbjct: 38  QDLEFHGVVRFYFQGGDGANVITKCIRVSSTATTRDVIDTLIEKFRPDMRMLTQNKYALY 217

Query: 95  EVHVS 99
           EVHV+
Sbjct: 218 EVHVN 232
>27345
          Length = 496

 Score = 65.9 bits (159), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 28/60 (46%), Positives = 42/60 (70%)
 Frame = +3

Query: 1039 KLGIYVKSVVKGGAADVDGRLAAGDQLLSVDGRSLVGLSQERAAELMTRTSSVVTLEVAK 1098
            KLGI++K++  GGAA  DGR+   DQ++ VDG+SLVG++Q  AA ++  TS  VT  + +
Sbjct: 18   KLGIFIKTLTDGGAAQKDGRIQVNDQIIEVDGKSLVGVTQAYAASVLRNTSGQVTFHIGR 197
>18965
          Length = 444

 Score = 58.2 bits (139), Expect = 3e-08,   Method: Composition-based stats.
 Identities = 34/87 (39%), Positives = 47/87 (54%)
 Frame = +2

Query: 458 VVTVTPRSMDAETYVDGQRISETTMLQSGMRLQFGTSHVFKFVDPIQDHVLSKRSVDGGL 517
           +VTVTP   DA+ YV+ +R+ +TTML+ G  +QFG  H FKFVDP  + V       G  
Sbjct: 2   IVTVTPTGRDADVYVEDERVVKTTMLRHGATVQFGRHHFFKFVDPRFEEVTKPDQSVGS- 178

Query: 518 MVKGPRHKPGAVQETTFELGGDVHSGT 544
                  +    QET F++ G V + T
Sbjct: 179 ------ERNMLHQETNFDVDGHVETVT 241

 Score = 37.0 bits (84), Expect = 0.080,   Method: Compositional matrix adjust.
 Identities = 15/33 (45%), Positives = 21/33 (63%)
 Frame = +1

Query: 601 LPASIEFRESSEDSFLSAIINYTNSSTVHFKLS 633
           LPAS++FR   ED  L A++   NS  + FKL+
Sbjct: 343 LPASLDFRLDVEDHLLQAVVQDVNSRNIQFKLA 441
>29705
          Length = 674

 Score = 50.4 bits (119), Expect = 7e-06,   Method: Compositional matrix adjust.
 Identities = 27/77 (35%), Positives = 44/77 (57%), Gaps = 4/77 (5%)
 Frame = -1

Query: 1026 GLSIVAAKGAGQDKL----GIYVKSVVKGGAADVDGRLAAGDQLLSVDGRSLVGLSQERA 1081
            G  I   +G G   +    GI++  V++GG+A+ DGR+A  D+LL+V+  +L  ++ E A
Sbjct: 419  GSGIQHCRGKGNQHIPGDNGIFITKVIEGGSAEQDGRIAVMDRLLAVNEHNLEDVTHEEA 240

Query: 1082 AELMTRTSSVVTLEVAK 1098
               +  T  VV L +AK
Sbjct: 239  VAALKSTGDVVRLTIAK 189
>20073
          Length = 582

 Score = 45.8 bits (107), Expect = 2e-04,   Method: Composition-based stats.
 Identities = 27/73 (36%), Positives = 39/73 (53%)
 Frame = +3

Query: 1024 GMGLSIVAAKGAGQDKLGIYVKSVVKGGAADVDGRLAAGDQLLSVDGRSLVGLSQERAAE 1083
            G+G +++  K   +    IY+  ++ GG AD    L  GDQLLSV+G S+ G   E+A E
Sbjct: 3    GLGFNVMGGK---EQSSPIYISRIIPGGVADRLNCLKRGDQLLSVNGVSVEGEYHEKAVE 173

Query: 1084 LMTRTSSVVTLEV 1096
            L+      V L V
Sbjct: 174  LLKLAQGSVRLVV 212
>30101
          Length = 459

 Score = 37.4 bits (85), Expect = 0.051,   Method: Compositional matrix adjust.
 Identities = 30/107 (28%), Positives = 56/107 (52%), Gaps = 4/107 (3%)
 Frame = -3

Query: 60  IRVSSTATTQDVIETLAEKFRPDMRMLSSPK-YSLYEVHVSGE-RRLDIDEKPLVVQLNW 117
           + V+S  TTQ+VI  + EK++ +    S+P+ +SL+ +H +GE +RL  +E PLV ++  
Sbjct: 418 VWVTSLVTTQEVINLVLEKYKVE----SAPENFSLFVMHDNGEQKRLKDNEYPLVTRITL 251

Query: 118 NKDDREGRFVLKN--ENDAIPAKKAQSNGPEKQEKEGVIQNFKRTLS 162
              +   R  L +  + D I  + AQ       E   ++  + + L+
Sbjct: 250 GPHEDVARLFLVDARKTDEISNEVAQFLNLSVPECRAILDRYDQELA 110
>37239
          Length = 453

 Score = 34.7 bits (78), Expect = 0.35,   Method: Composition-based stats.
 Identities = 14/25 (56%), Positives = 19/25 (76%)
 Frame = -3

Query: 1041 GIYVKSVVKGGAADVDGRLAAGDQL 1065
            GIY++ +  GGAA  DG+LA GD+L
Sbjct: 76   GIYIRHITIGGAAAKDGQLAVGDEL 2
>10472
          Length = 640

 Score = 30.0 bits (66), Expect = 8.3,   Method: Composition-based stats.
 Identities = 25/80 (31%), Positives = 37/80 (46%), Gaps = 3/80 (3%)
 Frame = +3

Query: 630 FKLSPTYVLYMACRYVLSSQHRPDISPTERTHKAIAVVNKMVSMMEGVIQEVDQVDQKQK 689
           FKL   Y +Y  C  VLSS+ + +  P  +    I  +  MVS+  G I  +D   QK K
Sbjct: 201 FKLINMYRIYNVCMNVLSSRRKSNSVPMYKCFSYILFI--MVSL--GNITIIDISSQKLK 368

Query: 690 NIAGALAF---WMANASELL 706
             +  + F   W  NA + +
Sbjct: 369 *YSICITFKKNWSVNACKCI 428
>08480
          Length = 698

 Score = 30.0 bits (66), Expect = 9.3,   Method: Compositional matrix adjust.
 Identities = 15/44 (34%), Positives = 25/44 (56%)
 Frame = -1

Query: 1051 GAADVDGRLAAGDQLLSVDGRSLVGLSQERAAELMTRTSSVVTL 1094
            G AD+ G L  GD++LSV+   +   + E+AA+ + R    V +
Sbjct: 698  GPADLSGDLRRGDKILSVNDVDVERATHEQAAQALKRAGDTVEI 567
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|149254026|ref|XP_132230.8| PREDICTED: SEC31-like 1
[Mus musculus]
         (1324 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

39827                                                                 173   4e-43
37142                                                                 142   1e-33
01805                                                                  60   7e-09
03387                                                                  54   6e-07
01768                                                                  53   1e-06
12841                                                                  45   2e-04
15745                                                                  44   6e-04
06799                                                                  43   8e-04
02960                                                                  42   0.001
27475                                                                  41   0.003
16105                                                                  40   0.007
00561                                                                  39   0.016
07741                                                                  39   0.021
20662                                                                  38   0.021
04395                                                                  37   0.040
11915                                                                  33   0.71 
35695                                                                  33   0.73 
14105                                                                  33   1.1  
20271                                                                  32   1.3  
10264                                                                  32   1.6  
19949                                                                  32   1.7  
01598                                                                  32   2.1  
29499                                                                  31   2.8  
05393                                                                  31   2.9  
12806                                                                  30   7.0  
>39827
          Length = 693

 Score =  173 bits (439), Expect = 4e-43,   Method: Compositional matrix adjust.
 Identities = 97/234 (41%), Positives = 142/234 (60%), Gaps = 30/234 (12%)
 Frame = -2

Query: 567 WSFLKVNFEEDSRGKYLELLGYRKEDLGQKIALALNK---------VDGPDVALKDSD-- 615
           W+FL+VNFE + R  +L+LLGY + +L +K+A A            VD  ++A K +   
Sbjct: 692 WNFLRVNFENEPRASFLQLLGYDQNELAKKVAEATGTDVAQPLSPGVDAKELAQKMTQLS 513

Query: 616 -------------QVAQSDGEESPAAEEQLLGERIKEE------KQECDFLPSAGGTFNI 656
                        Q + S G ++P + ++L G    +E      K+     P    T N 
Sbjct: 512 AGEERSPVYPPVGQASPSMGSKTPLSRDELSGSSAFDEIGGNQGKESGLQTPLVIPTEN- 336

Query: 657 SVSGDIDGLITRALLTGNFESAVDLCLHDNRMADAIILAIAGGQELLAQTQKKYFAKSQS 716
              GD  GL+ +ALL GNFE+AV++CL + +MA+AI+LAIAGG ELL +TQKKYF +++S
Sbjct: 335 ---GDSSGLMAQALLMGNFEAAVEMCLAEEKMAEAILLAIAGGPELLLRTQKKYFQRNKS 165

Query: 717 KITRLITAVVMKNWREIVESCDLKNWREALAAVLTYAKPDEFSALCDLLGTRLE 770
            + RLI++V+  +W  IVE+C+L NW+EALA +LTY+ P+EF+ALCD L  RLE
Sbjct: 164 NLGRLISSVITHDWTHIVETCELDNWKEALAVILTYSLPEEFTALCDTLAARLE 3
>37142
          Length = 327

 Score =  142 bits (357), Expect = 1e-33,   Method: Compositional matrix adjust.
 Identities = 65/109 (59%), Positives = 84/109 (77%)
 Frame = +2

Query: 182 VLIAGGENGNIILYDPSKIIAGDKEVVIAQKDKHTGPVRALDVNIFQTNLVASGANESEI 241
           V++ G +NG++++Y   K+I GD +  + Q  KHTG V+ALD N FQTNL+ASGA+ESEI
Sbjct: 2   VIVGGADNGSVLVYSAQKMIDGDADCSVLQLTKHTGAVKALDFNPFQTNLLASGASESEI 181

Query: 242 YIWDLNNFATPMTPGAKTQPPEDISCIAWNRQVQHILASASPSGRATVW 290
           YIWDLN    PMTPG K+QPPE++SC+AWNRQVQHILAS + + R  VW
Sbjct: 182 YIWDLNKPDNPMTPGQKSQPPEEVSCVAWNRQVQHILAS-NFAARCVVW 325
>01805
          Length = 2124

 Score = 59.7 bits (143), Expect = 7e-09,   Method: Compositional matrix adjust.
 Identities = 53/218 (24%), Positives = 91/218 (41%), Gaps = 20/218 (9%)
 Frame = -1

Query: 230 NLVASGANESEIYIWDLNNFAT---PMTPGA-----------------KTQPPEDISCIA 269
           N VA G+ E  I IWDL+   +    +T G+                  TQ   D+S   
Sbjct: 723 NFVAIGSMEPVIEIWDLDIMESVGPTLTLGSKPKKTKKKMKQKESVTGHTQAVLDLS--- 553

Query: 270 WNRQVQHILASASPSGRATVWDLRKNEPIIKVSDHSNRMHCSGLAWHPDVATQMVLASED 329
           WNR  +H+LASAS      +WDL + +  +  + HS  + C    WHP     ++  S D
Sbjct: 552 WNRNARHVLASASADTTVALWDLSEGKMAMNFTQHSREVQCCN--WHPQEEQTLLTGSFD 379

Query: 330 DRLPVIQMWDLRFASSPLRVLENHARGILAVAWSMADPELLLSCGKDAKILCSNPNTGEV 389
           + + V+   D R A +  +          AV W+  +P  LL+C     + C +    + 
Sbjct: 378 NTVKVV---DCRSAETCHKSWTVEGEVEKAV-WNHHNPLQLLACTDKGMVYCFDIRHEKP 211

Query: 390 LYELPTNTQWCFDIQWCPRNPAVLSAASFDGRISVYSI 427
           ++ +  ++     +    + P ++   S D  + V+ I
Sbjct: 210 VFSVGAHSSCVTGVCLSSQIPGLMITTSEDKTMKVWDI 97
>03387
          Length = 1891

 Score = 53.5 bits (127), Expect = 6e-07,   Method: Compositional matrix adjust.
 Identities = 52/221 (23%), Positives = 92/221 (41%), Gaps = 25/221 (11%)
 Frame = +1

Query: 232 VASGANESEIYIWDLNNF--------ATPMTPGAKTQPPEDISCIAWNRQVQHILASASP 283
           + S +++  I +WD+N+         A  +  G  T   ED+   AW+   + +  S + 
Sbjct: 409 LLSASDDHTICLWDINSTQRESRVVDAHTIFTG-HTSVVEDV---AWHLLHESLFGSVAD 576

Query: 284 SGRATVWDLRKN---EPIIKVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLPVIQMWDL 340
             +  +WD R N   +P   V  H+  ++C  L+++P     +   S D     + +WDL
Sbjct: 577 DQKLMIWDTRSNTTSKPSHVVDAHTAEVNC--LSFNPYSEFILATGSAD---KTVALWDL 741

Query: 341 RFASSPLRVLENHARGILAVAWSMADPELLLSCGKDAKI------------LCSNPNTG- 387
           R     L   E+H   I  V WS  +  +L S G D ++            L  +   G 
Sbjct: 742 RNLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLHVWDLSKIGEEQLPEDAEDGP 921

Query: 388 -EVLYELPTNTQWCFDIQWCPRNPAVLSAASFDGRISVYSI 427
            E+L+    +T    D  W P  P ++ + S D  + V+ +
Sbjct: 922 PELLFIHGGHTAKISDFSWNPNEPWIVCSVSEDNIMQVWQM 1044

 Score = 50.4 bits (119), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 45/180 (25%), Positives = 78/180 (43%), Gaps = 5/180 (2%)
 Frame = +1

Query: 166 LIWGPHKMDSKGDVSGVLIAGGENGNIILYDPSKIIAGDKEVVIAQK--DKHTGPVRALD 223
           L W P       +++G L++  ++  I L+D +     +  VV A      HT  V  + 
Sbjct: 379 LSWNP-------NLNGHLLSASDDHTICLWDINST-QRESRVVDAHTIFTGHTSVVEDVA 534

Query: 224 VNIFQTNLVASGANESEIYIWDLNNFATPMTPGAKTQPPEDISCIAWNRQVQHILASASP 283
            ++   +L  S A++ ++ IWD  +  T            +++C+++N   + ILA+ S 
Sbjct: 535 WHLLHESLFGSVADDQKLMIWDTRSNTTSKPSHVVDAHTAEVNCLSFNPYSEFILATGSA 714

Query: 284 SGRATVWDLRKNEPIIKVSDHSNRMHCSGL---AWHPDVATQMVLASEDDRLPVIQMWDL 340
                +WDLR     +K+  HS   H   +    W P   T +  +  D RL V   WDL
Sbjct: 715 DKTVALWDLRN----LKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLHV---WDL 873

 Score = 31.2 bits (69), Expect = 3.2,   Method: Compositional matrix adjust.
 Identities = 25/125 (20%), Positives = 49/125 (39%), Gaps = 11/125 (8%)
 Frame = +1

Query: 182 VLIAGGENGNIILYDPSKIIAGDKEVVIAQKDKHTGPVRALDVNIFQTNLVASGANESEI 241
           +L  G  +  + L+D   +     ++ +   + H   +  +  +     ++AS   +  +
Sbjct: 694 ILATGSADKTVALWDLRNL-----KLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRL 858

Query: 242 YIWDLNNFATPMTP-GAKTQPPE----------DISCIAWNRQVQHILASASPSGRATVW 290
           ++WDL+       P  A+  PPE           IS  +WN     I+ S S      VW
Sbjct: 859 HVWDLSKIGEEQLPEDAEDGPPELLFIHGGHTAKISDFSWNPNEPWIVCSVSEDNIMQVW 1038

Query: 291 DLRKN 295
            + +N
Sbjct: 1039QMAEN 1053
>01768
          Length = 1424

 Score = 52.8 bits (125), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 57/215 (26%), Positives = 90/215 (41%), Gaps = 20/215 (9%)
 Frame = +3

Query: 181 GVLIAGGENGNIILYDPSKIIAGDKEVVIAQKDKHTGPVRALDVNIFQTNLVASGANESE 240
           G L+ G   G I +  PS      ++   A    HT  V  +  +  + N+ AS + +  
Sbjct: 741 GWLVTGDCTGAIYISQPSSSGWTTEKSSYA---AHTDSVEDVQWSPNEGNVFASCSVDRT 911

Query: 241 IYIWDLNNFATPMTPGAKTQP---PEDISCIAWNRQVQHILASASPSGRATVWDLR--KN 295
           + IW  N    P      T P     DI+ I WN   +H+LAS    G   +WDLR  +N
Sbjct: 912 LRIW--NTQQKPSKANVLTVPEAHSRDINVINWNPIEKHLLASGGDDGIIKIWDLRMFRN 1085

Query: 296 EPIIKVSDHSNRMH---CSGLAWHPDVATQMVLASEDDRLPVIQMWDLRFASS------- 345
           +P+   +  S ++H    + L W+P  ++ +  + EDD+   I +WD             
Sbjct: 1086KPV--SAQASFKLHSQPVTSLEWNPQDSSVLAASGEDDQ---ITIWDFSVERDEGEGEEE 1250

Query: 346 ---PLRVLENHA--RGILAVAWSMADPELLLSCGK 375
              P ++L  H     I  V W    P +L+S  K
Sbjct: 1251LDVPAQLLFQHCGQTDIKEVHWHPQLPGVLISTAK 1355

 Score = 37.7 bits (86), Expect = 0.035,   Method: Compositional matrix adjust.
 Identities = 29/125 (23%), Positives = 59/125 (47%), Gaps = 10/125 (8%)
 Frame = +3

Query: 313 LAWHPDVATQMVLASEDDRLPVIQMWDLRFASSPLRVL---ENHARGILAVAWSMADPEL 369
           + W P+        S D  L   ++W+ +   S   VL   E H+R I  + W+  +  L
Sbjct: 855 VQWSPNEGNVFASCSVDRTL---RIWNTQQKPSKANVLTVPEAHSRDINVINWNPIEKHL 1025

Query: 370 LLSCGKDA-------KILCSNPNTGEVLYELPTNTQWCFDIQWCPRNPAVLSAASFDGRI 422
           L S G D        ++  + P + +  ++L  ++Q    ++W P++ +VL+A+  D +I
Sbjct: 1026LASGGDDGIIKIWDLRMFRNKPVSAQASFKL--HSQPVTSLEWNPQDSSVLAASGEDDQI 1199

Query: 423 SVYSI 427
           +++  
Sbjct: 1200TIWDF 1214
>12841
          Length = 1364

 Score = 45.1 bits (105), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 51/250 (20%), Positives = 94/250 (37%), Gaps = 30/250 (12%)
 Frame = +1

Query: 216 TGPVRALDVNIFQTNLVASGANESEIYIWDLNN------FATPMTPGAKTQPPEDISCIA 269
           T  V +LD ++   N++A+G  +  + I+++ +           T G    P   I  I 
Sbjct: 553 THGVTSLDFSVANANILAAGYYDGGVAIYNVRSTSDEPILDNQETHGKHLGPVWQIQWIE 732

Query: 270 WNR----QVQHILASASPSGRATVWDLRK---NEPIIKVSDHSNRM-------------- 308
             R    +   +L S S  GR T W +RK   +  I+++     RM              
Sbjct: 733 KERGSGEERAEVLISISTDGRVTQWSIRKGFESNNIMRLKKLPTRMAGKAREKKGEAFIS 912

Query: 309 -HCSGLAW--HPDVATQMVLASEDDRLPVIQMWDLRFASSPLRVLENHARGILAVAWSMA 365
            H  GL +  H       +  +E+     I      +    L     H   +  + WS  
Sbjct: 913 RHAGGLCFDFHSRDLNVYLAGTEE---GYIHKCSCSYNEQYLETYSGHTAPVYHIRWSPF 1083

Query: 366 DPELLLSCGKDAKILCSNPNTGEVLYELPTNTQWCFDIQWCPRNPAVLSAASFDGRISVY 425
             ++ LSC  D  I   + +    +    ++T+   D+ W PR+  V  A   +G + V+
Sbjct: 1084VSDIFLSCSADWSIRLWHQDRTTPILTFHSSTKTVHDVCWSPRSSTVF-ACVHEGAVEVW 1260

Query: 426 SIMGGSIDGL 435
            +   ++D +
Sbjct: 1261DLAQSTLDAV 1290
>15745
          Length = 1183

 Score = 43.5 bits (101), Expect = 6e-04,   Method: Compositional matrix adjust.
 Identities = 34/135 (25%), Positives = 60/135 (44%), Gaps = 8/135 (5%)
 Frame = +2

Query: 235 GANESEIYIWDLNNFATP------MTPGAKTQPPEDISCIAWNRQVQHILASASPSGRAT 288
           G  E  + +WDLN  ++       +T   K QP   ++C  WN    H  A  + +  AT
Sbjct: 485 GVCEDRVIMWDLNVASSSAQQTDMITLEGKGQPR--LTCGRWN--PHHNCAQIATANEAT 652

Query: 289 V--WDLRKNEPIIKVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLPVIQMWDLRFASSP 346
           +  WDLR  +   ++     ++    L ++P+    +    +D R   ++ WD R  S P
Sbjct: 653 IRGWDLRSKQQTYQMEGAHGQL-VRDLDFNPNRQYYLASCGDDCR---VKFWDTRNCSEP 820

Query: 347 LRVLENHARGILAVA 361
           L+VL +H+  +    
Sbjct: 821 LKVLSDHSHWVWGCG 865

 Score = 33.9 bits (76), Expect = 0.47,   Method: Compositional matrix adjust.
 Identities = 18/42 (42%), Positives = 23/42 (54%)
 Frame = +2

Query: 304 HSNRMHCSGLAWHPDVATQMVLASEDDRLPVIQMWDLRFASS 345
           HS+     G+ WHP   +Q VL   +DR   + MWDL  ASS
Sbjct: 419 HSSDHDVKGILWHPTGDSQTVLGVCEDR---VIMWDLNVASS 535
>06799
          Length = 616

 Score = 43.1 bits (100), Expect = 8e-04,   Method: Compositional matrix adjust.
 Identities = 36/120 (30%), Positives = 57/120 (47%), Gaps = 6/120 (5%)
 Frame = +3

Query: 180 SGVLIAGGENGNI-ILYDPSKIIAG-----DKEVVIAQKDKHTGPVRALDVNIFQTNLVA 233
           S  L  G E GN+ I+   S I++G     +K + +++K  H GPV  L  N   +N + 
Sbjct: 150 SKWLYIGTERGNVHIVNIESFILSGYIINWNKAIELSRKT-HPGPVVHLSDNPVDSNKLL 326

Query: 234 SGANESEIYIWDLNNFATPMTPGAKTQPPEDISCIAWNRQVQHILASASPSGRATVWDLR 293
            G     I +WDL + A       +   PE +  IAW+ + +  + S S  G  T W+L+
Sbjct: 327 IGFESGAIVLWDLRSKAAE----CRYNSPEALRSIAWHFEGKQFMCSHS-DGSLTTWNLK 491
>02960
          Length = 1577

 Score = 42.4 bits (98), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 42/150 (28%), Positives = 70/150 (46%), Gaps = 2/150 (1%)
 Frame = +2

Query: 232  VASGANESEIYIWDLNNFA-TPMTPGAKTQPPEDISCIAWNRQVQHILASASPSGRATVW 290
            V + + +  + +WDL+    T +  G+K       S ++      H+L + S      + 
Sbjct: 1001 VVTSSWDHSLRLWDLHTAQQTSLIQGSKAVLDVAYSPLS------HMLITGSADRHVRLV 1162

Query: 291  DLRKNE-PIIKVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLPVIQMWDLRFASSPLRV 349
            D R +E   +K +  S+    +G+ W P      +  S D+   V+++WD R   + L  
Sbjct: 1163 DPRCSEGETVKCAFTSHTGWVTGVDWSPTREHLFLSGSYDN---VLKLWDTRSPKATLYD 1333

Query: 350  LENHARGILAVAWSMADPELLLSCGKDAKI 379
            +  H   ILAV WS+  PELLLS G D K+
Sbjct: 1334 MNWHEDRILAVDWSI--PELLLSGGVDNKL 1417

 Score = 32.0 bits (71), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 19/67 (28%), Positives = 34/67 (50%)
 Frame = +2

Query: 179  VSGVLIAGGENGNIILYDPSKIIAGDKEVVIAQKDKHTGPVRALDVNIFQTNLVASGANE 238
            +S +LI G  + ++ L DP      + E V      HTG V  +D +  + +L  SG+ +
Sbjct: 1112 LSHMLITGSADRHVRLVDPR---CSEGETVKCAFTSHTGWVTGVDWSPTREHLFLSGSYD 1282

Query: 239  SEIYIWD 245
            + + +WD
Sbjct: 1283 NVLKLWD 1303
>27475
          Length = 369

 Score = 40.8 bits (94), Expect = 0.003,   Method: Composition-based stats.
 Identities = 26/69 (37%), Positives = 37/69 (53%)
 Frame = +2

Query: 311 SGLAWHPDVATQMVLASEDDRLPVIQMWDLRFASSPLRVLENHARGILAVAWSMADPELL 370
           +G+ W P      +  S D+   V+++WD R   + L  +  H   ILAV WS+  PELL
Sbjct: 80  TGVDWSPTREHLFLSGSYDN---VLKLWDTRSPKATLYDMNWHEDRILAVDWSI--PELL 244

Query: 371 LSCGKDAKI 379
           LS G D K+
Sbjct: 245 LSGGVDNKL 271
>16105
          Length = 960

 Score = 39.7 bits (91), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 26/128 (20%), Positives = 57/128 (44%), Gaps = 6/128 (4%)
 Frame = -2

Query: 215 HTGPVRALDVNIFQTNLVASGANESEIYIWDL------NNFATPMTPGAKTQPPEDISCI 268
           H G V  +       N++AS +++  + +W +       N   P+      Q  +    I
Sbjct: 578 HKGAVLDIQWCPHNDNVIASASDDCTVKVWQIPDSGLVTNLTDPVVDLVGHQ--KRCCLI 405

Query: 269 AWNRQVQHILASASPSGRATVWDLRKNEPIIKVSDHSNRMHCSGLAWHPDVATQMVLASE 328
            W+   Q++L SA    +   W++   EP+++V D  + ++C    ++    +++V   +
Sbjct: 404 VWHPSAQNVLVSAGADNKILFWNVGTGEPMLEV-DVPDMIYCMSFNFN---GSRLVCTCK 237

Query: 329 DDRLPVIQ 336
           D +L +I 
Sbjct: 236 DKKLRIID 213

 Score = 33.1 bits (74), Expect = 0.69,   Method: Compositional matrix adjust.
 Identities = 13/27 (48%), Positives = 18/27 (66%)
 Frame = -2

Query: 401 FDIQWCPRNPAVLSAASFDGRISVYSI 427
            DIQWCP N  V+++AS D  + V+ I
Sbjct: 563 LDIQWCPHNDNVIASASDDCTVKVWQI 483

 Score = 33.1 bits (74), Expect = 0.81,   Method: Compositional matrix adjust.
 Identities = 24/84 (28%), Positives = 39/84 (46%), Gaps = 3/84 (3%)
 Frame = -2

Query: 313 LAWHPDVATQMVLASEDDRLPVIQMWDLRFASS---PLRVLENHARGILAVAWSMADPEL 369
           + W P     +  AS+D  + V Q+ D    ++   P+  L  H +    + W  +   +
Sbjct: 557 IQWCPHNDNVIASASDDCTVKVWQIPDSGLVTNLTDPVVDLVGHQKRCCLIVWHPSAQNV 378

Query: 370 LLSCGKDAKILCSNPNTGEVLYEL 393
           L+S G D KIL  N  TGE + E+
Sbjct: 377 LVSAGADNKILFWNVGTGEPMLEV 306
>00561
          Length = 1003

 Score = 38.5 bits (88), Expect = 0.016,   Method: Compositional matrix adjust.
 Identities = 42/168 (25%), Positives = 75/168 (44%), Gaps = 1/168 (0%)
 Frame = -3

Query: 230 NLVASGANESEIYIWDLNNFATPMTPGAKTQPPEDISCIAWNRQVQHILASASPSGRATV 289
           N   SG+ +  + +WDL    T       T+    ++  A NRQ+     S S      +
Sbjct: 827 NYALSGSWDQTLRLWDLAAGKTTRRFEGHTKDVLSVAFSADNRQI----VSGSRDKTIKL 660

Query: 290 WD-LRKNEPIIKVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLPVIQMWDLRFASSPLR 348
           W+ L + +  I+   H++ + C   +  P+ +  ++++   DR   +++W+L  A+  L+
Sbjct: 659 WNTLAECKFTIQEDGHTDWVSCVRFS--PNHSNPIIVSCGWDR--TVKVWNL--ANCKLK 498

Query: 349 VLENHARGILAVAWSMADPELLLSCGKDAKILCSNPNTGEVLYELPTN 396
              +   G L       D  L  S GKD+K L  + N G+ LY L  N
Sbjct: 497 NNHHGHNGYLNTVTVSPDGSLCTSGGKDSKALLWDLNDGKNLYTLEHN 354
>07741
          Length = 2119

 Score = 38.5 bits (88), Expect = 0.021,   Method: Compositional matrix adjust.
 Identities = 25/110 (22%), Positives = 49/110 (44%), Gaps = 11/110 (10%)
 Frame = +1

Query: 342 FASSPLRVLENHARGILAVAWSMADPELLLSCGKDAKI-LCSN----PNTG------EVL 390
           + S  +  L++H   +  VAW+   P++  +C  D  + +  N     +TG      + L
Sbjct: 205 YTSHFIDTLDSHNMAVYKVAWNHYHPKIYATCSADWNVKIWENGGKPTDTGXDSLSRKPL 384

Query: 391 YELPTNTQWCFDIQWCPRNPAVLSAASFDGRISVYSIMGGSIDGLRQKQV 440
           +    N     D+ W P +  V +A + DG++ VY +     + L ++ V
Sbjct: 385 FSFDLNNS-VGDVAWAPYSSTVFAAVTADGKVCVYDLSVNKYEPLCEQMV 531
>20662
          Length = 1220

 Score = 38.1 bits (87), Expect = 0.021,   Method: Compositional matrix adjust.
 Identities = 27/115 (23%), Positives = 49/115 (42%), Gaps = 4/115 (3%)
 Frame = +2

Query: 268 IAWNRQVQ----HILASASPSGRATVWDLRKNEPIIKVSDHSNRMHCSGLAWHPDVATQM 323
           I W+ Q       +  S S  G+  +WD+R+++P   +   S+    + + W P+     
Sbjct: 515 IVWDVQCHPTEPALFLSCSQDGKIVLWDVRESKPATCLPKCSSGFKPTCVQWQPNARNMY 694

Query: 324 VLASEDDRLPVIQMWDLRFASSPLRVLENHARGILAVAWSMADPELLLSCGKDAK 378
            +  E   + V    DLR         ++H R +  +A+    P +L S G+D K
Sbjct: 695 AVGDEGGHVSVQ---DLRMVVEKNVSYQSHNRVVTRLAFCPQRPSMLASIGEDCK 850
>04395
          Length = 1145

 Score = 37.4 bits (85), Expect = 0.040,   Method: Compositional matrix adjust.
 Identities = 32/138 (23%), Positives = 58/138 (42%), Gaps = 11/138 (7%)
 Frame = +3

Query: 182 VLIAGGENGNIILYDPSKIIAGDKEVVIAQKDKHTGPVRALD---------VNIFQTNLV 232
           VL++GGE+G + L  P                 H  PVR ++         +   + + V
Sbjct: 252 VLMSGGEDGRLALLSPG----------------HATPVRLMEKADSCTINALTFLKQSQV 383

Query: 233 ASGANESEIYIWDL-NNFATPMTPGAKTQPPEDISCIAWNRQVQHILASASPSGRATVWD 291
            +  +  ++ ++D+  N   P    + T     + C+  +    HI+A+ S  G  TVWD
Sbjct: 384 LTVNSFGQLKLFDVRQNSDEPAQIFSATDDHWSLLCVDKHPGQLHIVATGSQDGTLTVWD 563

Query: 292 LRKNE-PIIKVSDHSNRM 308
           LR +  P+  +  H + M
Sbjct: 564 LRHHRFPMTTLDAHHSSM 617
>11915
          Length = 737

 Score = 33.1 bits (74), Expect = 0.71,   Method: Composition-based stats.
 Identities = 20/76 (26%), Positives = 38/76 (50%), Gaps = 5/76 (6%)
 Frame = +1

Query: 270 WNRQVQH-----ILASASPSGRATVWDLRKNEPIIKVSDHSNRMHCSGLAWHPDVATQMV 324
           W RQ Q+     +LA+   SGR  +W+    + +I++ DH   +H   L +  D +  ++
Sbjct: 412 WKRQQQNDSSTLVLATGHVSGRIKLWNCETGKLLIEMMDHKATVH--DLHFAADNSLCLM 585

Query: 325 LASEDDRLPVIQMWDL 340
            AS D     +++W+ 
Sbjct: 586 SASHDG---TVKLWEF 624
>35695
          Length = 1651

 Score = 33.1 bits (74), Expect = 0.73,   Method: Composition-based stats.
 Identities = 32/125 (25%), Positives = 54/125 (43%)
 Frame = -1

Query: 213  DKHTGPVRALDVNIFQTNLVASGANESEIYIWDLNNFATPMTPGAKTQPPEDISCIAWNR 272
            D H G + AL       N+V S + +  I +W+ +     + P  + + P +   +A + 
Sbjct: 1594 DAHFGRIIALTSVTVGCNMVISSSIDKTINVWNFDKILEEVHPLDRMERPIETVHMAASS 1415

Query: 273  QVQHILASASPSGRATVWDLRKNEPIIKVSDHSNRMHCSGLAWHPDVATQMVLASEDDRL 332
                 L  A+   + +VWDL     ++KV   S+R +    A+     T  VL +E   L
Sbjct: 1414 S----LCVATTRNQTSVWDLETGR-LVKVLVGSSRSNXVSQAFITREGTH-VLTAESPSL 1253

Query: 333  PVIQM 337
             V QM
Sbjct: 1252 LVWQM 1238
>14105
          Length = 429

 Score = 32.7 bits (73), Expect = 1.1,   Method: Composition-based stats.
 Identities = 11/38 (28%), Positives = 22/38 (57%)
 Frame = +3

Query: 390 LYELPTNTQWCFDIQWCPRNPAVLSAASFDGRISVYSI 427
           LY    N+ +  D+ W P +PA+ +A    GR+ ++++
Sbjct: 30  LYSFEDNSDYVMDVAWSPVHPALFAAVDGSGRLDLWNL 143
>20271
          Length = 567

 Score = 32.3 bits (72), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 15/53 (28%), Positives = 25/53 (47%)
 Frame = -1

Query: 375 KDAKILCSNPNTGEVLYELPTNTQWCFDIQWCPRNPAVLSAASFDGRISVYSI 427
           K+ K +CS             N+ +  D+QW P NPA+ S     GR+ ++ +
Sbjct: 177 KEQKYVCS----------FEDNSDYVSDVQWSPTNPALFSCVDIMGRLDLWHL 49
>10264
          Length = 416

 Score = 32.0 bits (71), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 21/93 (22%), Positives = 42/93 (45%)
 Frame = -1

Query: 160 SHRYHKLIWGPHKMDSKGDVSGVLIAGGENGNIILYDPSKIIAGDKEVVIAQKDKHTGPV 219
           S R   + W PH  D++      L++ G +    ++D  K  A      +AQ   H G +
Sbjct: 245 SQRVTDMSWSPHH-DAR------LVSVGYDAEAFVWDVQKGTA------LAQFKGHMGRL 105

Query: 220 RALDVNIFQTNLVASGANESEIYIWDLNNFATP 252
                +    +LV +G +++ +++W ++  A P
Sbjct: 104 LTCQFSGLDPDLVMTGGSDASVHVWRVSQQAAP 6
>19949
          Length = 903

 Score = 32.0 bits (71), Expect = 1.7,   Method: Compositional matrix adjust.
 Identities = 31/123 (25%), Positives = 58/123 (47%), Gaps = 1/123 (0%)
 Frame = +2

Query: 219 VRALDVNIFQTNLVASGANESEIYIWDLNNFATPMTPGAKTQPPEDISCIAWNRQVQHIL 278
           V++LD + +     ASG+ +  + +WD+       T    T     + C+ ++   + I 
Sbjct: 2   VKSLDFHPYGA-YTASGSMDCNVKLWDIRRKGCIYTYKGHTGC---VCCLRFSPDGRWI- 166

Query: 279 ASASPSGRATVWDLRKNEPIIKVSDHSNRMHCSGLAWHPDVATQMVLAS-EDDRLPVIQM 337
           ASAS  G   +WDL   + +  +  H + +  + + +HP    + +LAS   DR   ++ 
Sbjct: 167 ASASEDGLVKLWDLTAGKLLTDLKLHRDAV--NTIEFHPH---EFLLASGSADR--TVKF 325

Query: 338 WDL 340
           WDL
Sbjct: 326 WDL 334
>01598
          Length = 1545

 Score = 31.6 bits (70), Expect = 2.1,   Method: Compositional matrix adjust.
 Identities = 21/93 (22%), Positives = 42/93 (45%)
 Frame = +1

Query: 160  SHRYHKLIWGPHKMDSKGDVSGVLIAGGENGNIILYDPSKIIAGDKEVVIAQKDKHTGPV 219
            S R   + W PH  D++      L++ G +    ++D  K  A      +AQ   H G +
Sbjct: 1300 SQRVTDMSWSPHH-DAR------LVSVGYDAEAFVWDVQKGTA------LAQFKGHMGRL 1440

Query: 220  RALDVNIFQTNLVASGANESEIYIWDLNNFATP 252
                 +    +LV +G +++ +++W ++  A P
Sbjct: 1441 LTCQFSGLDPDLVMTGGSDASVHVWRVSQQAAP 1539

 Score = 29.6 bits (65), Expect = 8.9,   Method: Compositional matrix adjust.
 Identities = 52/219 (23%), Positives = 82/219 (37%), Gaps = 21/219 (9%)
 Frame = +1

Query: 231 LVASGANESEIYIWDLNN---FATPMTPGAKTQPPEDIS------CIAWNRQVQHILASA 281
           L+A+G+ +  I +W L+          P  + +  +  S       I W +     L S+
Sbjct: 106 LIATGSKDRTIRVWTLSQGKQIFMKKLPNQRREAGDTGSRFKVWLAIHWLKSNPEQLVSS 285

Query: 282 SPSGRATVWDLRKNE----PIIKVSDHSNRMH--CSGLAWHPDVATQMVLASEDDRLPVI 335
           S  G   +W LR  +       + SD+   M    +  A  PD  T    A   DR  V 
Sbjct: 286 SSGGDLLLWSLRYTKGQAYQTFQTSDYRPHMRPVFNICASGPDSKTLCTFAQ--DRQVV- 456

Query: 336 QMWDLRF--ASSPLRVLENHARGILAVAWSMADPELLLSCGKDAKILCSNPNTGEVLYEL 393
            +WDL    A + +  L  H   +  V  S  DP  +     D+ I   N +     Y++
Sbjct: 457 -LWDLETMEAVASMATLGGH---VYCVRTSPIDPGRVAVGVGDSMIRTWNMSNKTNPYDV 624

Query: 394 PTNTQW----CFDIQWCPRNPAVLSAASFDGRISVYSIM 428
            T  Q        + W P     L   + DGRI V+ ++
Sbjct: 625 TTLWQGIKSKVTAVAWHPTKEGWLGFGTDDGRIGVFDVL 741
>29499
          Length = 683

 Score = 31.2 bits (69), Expect = 2.8,   Method: Composition-based stats.
 Identities = 18/57 (31%), Positives = 31/57 (54%), Gaps = 4/57 (7%)
 Frame = +1

Query: 1243 TKRKLDDASKRLEFLYD----KLREQTLSPTIINGLHSIARSIETRNYSEGLSVHTH 1295
            T   L ++ + L ++Y+    + RE  LSP   + +H++  S +   Y+ GLSVH H
Sbjct: 139  TATSLINSQQSLHYMYNIFL*RFREMHLSP--FHYIHNLILSYKEHEYT*GLSVHWH 303
>05393
          Length = 904

 Score = 31.2 bits (69), Expect = 2.9,   Method: Composition-based stats.
 Identities = 18/72 (25%), Positives = 33/72 (45%)
 Frame = +1

Query: 270 WNRQVQHILASASPSGRATVWDLRKNEPIIKVSDHSNRMHCSGLAWHPDVATQMVLASED 329
           WN      L + +  G    +D+R  +P+  V  HS+ +  +G+     +   M+  SED
Sbjct: 115 WNHHNPLQLLACTDKGMVYCFDIRHEKPVFSVGAHSSCV--TGVCLSSQIPGLMITTSED 288

Query: 330 DRLPVIQMWDLR 341
             + V   WD++
Sbjct: 289 KTMKV---WDIQ 315
>12806
          Length = 961

 Score = 30.0 bits (66), Expect = 7.0,   Method: Compositional matrix adjust.
 Identities = 47/224 (20%), Positives = 99/224 (44%), Gaps = 8/224 (3%)
 Frame = +3

Query: 183 LIAGGENGNIILYD--PSKIIAGDKEVVIAQK--DKHTGPVRALDVNIFQTNLVASGANE 238
           LI+GG + NII++D  P K    D+   + +K    H+  +  L ++   +    S + +
Sbjct: 54  LISGGRDNNIIVWDL*PKKDGDEDQTWGVPRKTLTGHSHFISDLALSA-DSRFALSSSWD 230

Query: 239 SEIYIWDLNNFATPMTPGAKTQPPEDISCIAW---NRQVQHILASASPSGRATVWDLR-K 294
           + + +WD+   +T       T+   D+  +A+   NRQ+    AS        +W++  +
Sbjct: 231 ATLRLWDIKKGSTTSRFINHTR---DVLTVAFSPDNRQI----ASGGRDKNLKIWNIMGE 389

Query: 295 NEPIIKVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLPVIQMWDLRFASSPLRVLENHA 354
            +  +  + H++ + C  + +H D    +V+++ +D+   I++WD     +       H 
Sbjct: 390 CKYTVDANAHTDWVTC--VRFHQDTKNPIVVSASNDK--TIKVWD-NHTMTLKNTFVGHK 554

Query: 355 RGILAVAWSMADPELLLSCGKDAKILCSNPNTGEVLYELPTNTQ 398
             I A+  S      L+S  KD   +  N   G  + ++  + Q
Sbjct: 555 AQITALDMS---TNYLVSGSKDGIAMTWNVAEGSFVGKIDCDDQ 677
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6678143|ref|NP_033304.1| Sjogren syndrome antigen B
[Mus musculus]
         (415 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

35180                                                                 169   5e-43
13157                                                                  79   2e-15
00781                                                                  61   1e-09
27594                                                                  57   1e-08
32379                                                                  49   3e-06
19586                                                                  29   3.7  
>35180
          Length = 2181

 Score =  169 bits (428), Expect(2) = 5e-43,   Method: Compositional matrix adjust.
 Identities = 88/172 (51%), Positives = 117/172 (68%), Gaps = 1/172 (0%)
 Frame = -2

Query: 25  FGDFNLPRDKFLKEQIKLDEGWVPLETMIKFNRLNRLTTDFNVIVQALSKSKAKLMEVSA 84
           FGD NLPRDKFL+E+ + D+GWV ++TM+ FNRL +++ D   I +AL KS A LMEV+ 
Sbjct: 518 FGDVNLPRDKFLQEKTREDDGWVSMDTMLNFNRLKQISDDKEAICKALQKSTAGLMEVNE 339

Query: 85  DKTKIRRSPSRPLPEVTDEYKNDVKNRSVYIKGFPTDATLDDIKEWLDDKGQILNIQMRR 144
           D TKIRR PS+PLP+ T E K+D+ +RSVY+KGFP D TLD + E+ +  G+I  I MRR
Sbjct: 338 DMTKIRRCPSKPLPDNTKERKDDINSRSVYVKGFPEDITLDTLMEFFEQHGKIDTILMRR 159

Query: 145 TL-HKTFKGSIFAVFDSIQSAKKFVEIPGQKYKDTNLLILFKEDYFAKKNEE 195
               K FKGS+F  F + +    F+     KY DT L+ + KE+YF KK EE
Sbjct: 158 NRPDKNFKGSVFVTFSNKEEEDVFLG-KDVKYNDTELIKMTKEEYFKKKTEE 6

 Score = 23.5 bits (49), Expect(2) = 5e-43,   Method: Compositional matrix adjust.
 Identities = 10/24 (41%), Positives = 15/24 (62%)
 Frame = -3

Query: 2   AENGDNEKMTALEAKICHQIEYYF 25
           A NGD   ++ +E K+  Q+EYY 
Sbjct: 580 ASNGD--ALSEMEKKVIRQVEYYL 515
>13157
          Length = 552

 Score = 79.3 bits (194), Expect = 2e-15,   Method: Compositional matrix adjust.
 Identities = 34/69 (49%), Positives = 50/69 (72%)
 Frame = +1

Query: 2   AENGDNEKMTALEAKICHQIEYYFGDFNLPRDKFLKEQIKLDEGWVPLETMIKFNRLNRL 61
           A NGD   ++ +E K+  Q+EYYFGD NLPRDKFL+E+ + D+GWV ++TM+ FNRL ++
Sbjct: 352 ASNGD--ALSEMEKKVIRQVEYYFGDVNLPRDKFLQEKTREDDGWVSMDTMLNFNRLKQI 525

Query: 62  TTDFNVIVQ 70
           + D   I +
Sbjct: 526 SDDKEAICK 552
>00781
          Length = 3170

 Score = 60.8 bits (146), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 45/167 (26%), Positives = 85/167 (50%), Gaps = 15/167 (8%)
 Frame = -1

Query: 19   HQIEYYFGDFNLPRDKFLKEQIKLD-EGWVPLETMIKFNRLNRLTTDF----------NV 67
            +Q+E+YFGD NL +D+F+K++I  D +G++PL   + F ++  L              ++
Sbjct: 3008 NQMEFYFGDANLSKDRFMKQEIDRDPDGYIPLSVFLSFGKIMELCASVDTKKEGWMPQDL 2829

Query: 68   IVQALSKSKAKLMEVSADKTKIRR-SPSRPLPEVTDEYKNDVKNRSVYIKGFPTDATLDD 126
            ++++L  S   +++V  D++K+RR +P R L       + +   R+VY++GF    + + 
Sbjct: 2828 LIKSLKLS--DMLQVREDESKVRRITPIRFL------TQEETDARTVYVEGFHKFTSREW 2673

Query: 127  IKEWLDDKGQILNIQMRRTLHKT---FKGSIFAVFDSIQSAKKFVEI 170
            I       G +  + +     KT    KG  F  F S + A K V++
Sbjct: 2672 ISRMFSKCGTVTYVSL--PCFKTTREIKGYAFVEFQSPEEAVKAVQM 2538
>27594
          Length = 515

 Score = 57.0 bits (136), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 22/34 (64%), Positives = 30/34 (88%)
 Frame = +3

Query: 20  QIEYYFGDFNLPRDKFLKEQIKLDEGWVPLETMI 53
           Q+EYYFGD NLPRDKFL+E+ + D+GWV ++TM+
Sbjct: 411 QVEYYFGDVNLPRDKFLQEKTREDDGWVSMDTML 512
>32379
          Length = 581

 Score = 49.3 bits (116), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 30/90 (33%), Positives = 52/90 (57%), Gaps = 7/90 (7%)
 Frame = +3

Query: 17  ICHQIEYYFGDFNLPRDKFLKEQIKLDEGWVPLETMIKFNRLNRLTTDF----NVIVQAL 72
           +  Q+EYY  + NL +D FL+ ++K  EGWVP+  +  FNR+  L+ +     +V++Q +
Sbjct: 231 LITQVEYYLSEDNLSKDFFLRRRMK-PEGWVPMNLIATFNRMINLSRNMGLIKDVLIQTV 407

Query: 73  SKSKAKLMEVSADKTKIR---RSPSRPLPE 99
             S+   +E+S D+  +R   +    PLPE
Sbjct: 408 KASEK--LELSPDEEFVRPREKPEIWPLPE 491
>19586
          Length = 989

 Score = 28.9 bits (63), Expect = 3.7,   Method: Compositional matrix adjust.
 Identities = 12/24 (50%), Positives = 16/24 (66%)
 Frame = +2

Query: 13  LEAKICHQIEYYFGDFNLPRDKFL 36
           L  KI  Q+E+YF D N+ +D FL
Sbjct: 380 LRNKIIKQVEFYFSDANILKDVFL 451
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|134288904|ref|NP_034717.2| intersectin 1 isoform 1
[Mus musculus]
         (1714 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

20131                                                                 173   6e-43
30482                                                                 103   7e-22
19303                                                                  75   2e-13
01130                                                                  73   1e-12
12324                                                                  65   3e-10
16716                                                                  60   6e-09
36305                                                                  57   6e-08
17286                                                                  54   6e-07
01494                                                                  54   8e-07
29687                                                                  51   3e-06
32146                                                                  50   1e-05
18372                                                                  49   3e-05
11641                                                                  48   3e-05
26032                                                                  47   5e-05
13664                                                                  46   1e-04
33143                                                                  45   2e-04
19469                                                                  45   2e-04
18050                                                                  43   0.001
30740                                                                  42   0.002
28095                                                                  42   0.002
17768                                                                  41   0.005
15115                                                                  40   0.008
21187                                                                  39   0.015
14539                                                                  39   0.021
38272                                                                  39   0.021
29243                                                                  38   0.027
19562                                                                  38   0.041
31183                                                                  38   0.046
07198                                                                  37   0.066
27252                                                                  35   0.20 
13641                                                                  35   0.26 
05050                                                                  32   3.0  
20374                                                                  31   3.4  
18881                                                                  31   3.7  
36643                                                                  31   3.9  
07591                                                                  31   3.9  
05206                                                                  31   4.8  
14594                                                                  31   5.0  
11228                                                                  30   6.1  
05237                                                                  30   7.4  
>20131
          Length = 574

 Score =  173 bits (438), Expect = 6e-43,   Method: Compositional matrix adjust.
 Identities = 87/160 (54%), Positives = 114/160 (71%), Gaps = 1/160 (0%)
 Frame = -2

Query: 997  GEEFIAMYTYESSEQGDLTFQQGDVIVVTKKDGDWWTGTVGDKSGVFPSNYVR-LKDSEG 1055
            GE ++AMY+Y S E  DLTF +GD+I+VTKKD DWWTGT+G+K+G+FPS YV+ ++   G
Sbjct: 483  GEYYVAMYSYVSGETADLTFNEGDMILVTKKDEDWWTGTLGEKTGMFPSTYVKKVEIQPG 304

Query: 1056 SGTAGKTGSLGKKPEIAQVIASYAATGPEQLTLAPGQLILIRKKNPGGWWEGELQARGKK 1115
              +A       KKPEIA VIA Y ATG  QL+L PG LI +R+K+P GWWEGELQARG++
Sbjct: 303  QKSA-------KKPEIAMVIAPYTATGNGQLSLEPGNLIHVRQKSPRGWWEGELQARGQR 145

Query: 1116 RQIGWFPANYVKLLSPGTSKITPTELPKTAVQPAVCQVIG 1155
            ++IGWFPA+YVK L   +++ TP   PK A+     Q  G
Sbjct: 144  KKIGWFPADYVKPLGSSSARSTPD--PKVALSAGQQQSAG 31

 Score = 66.6 bits (161), Expect = 8e-11,   Method: Compositional matrix adjust.
 Identities = 48/142 (33%), Positives = 73/142 (51%), Gaps = 5/142 (3%)
 Frame = -2

Query: 1067 KKPEIAQVIASYAATGPEQLTLAPGQLILIRKKNPGGWWEGELQARGKKRQIGWFPANYV 1126
            K+ E    + SY +     LT   G +IL+ KK+   WW G L   G+K   G FP+ YV
Sbjct: 489  KEGEYYVAMYSYVSGETADLTFNEGDMILVTKKDED-WWTGTL---GEK--TGMFPSTYV 328

Query: 1127 KLLSPGTSKITPTELPKTAVQPAVCQVIGMYDYTAQNDDELAFSKGQIINVLNKEDPDWW 1186
            K +     +I P +  K+A +P +  VI    YTA  + +L+   G +I+V  K    WW
Sbjct: 327  KKV-----EIQPGQ--KSAKKPEIAMVIA--PYTATGNGQLSLEPGNLIHVRQKSPRGWW 175

Query: 1187 KGEVSG-----QVGLFPSNYVK 1203
            +GE+       ++G FP++YVK
Sbjct: 174  EGELQARGQRKKIGWFPADYVK 109

 Score = 53.5 bits (127), Expect = 7e-07,   Method: Compositional matrix adjust.
 Identities = 42/153 (27%), Positives = 71/153 (46%), Gaps = 7/153 (4%)
 Frame = -2

Query: 904  EKVEGLQAQALYPWRAKKDNHLNFNKSDVITVLEQQDMWWFGEVQGQKGWFPKSYVKLIS 963
            ++ EG    A+Y + + +   L FN+ D+I V ++ + WW G +  + G FP +YVK + 
Sbjct: 495  DRKEGEYYVAMYSYVSGETADLTFNEGDMILVTKKDEDWWTGTLGEKTGMFPSTYVKKVE 316

Query: 964  -GPVRKSTSIDTGPTESPASLKRVASPAAKPAIPGEEFIAMYTYESSEQGDLTFQQGDVI 1022
              P +KS                    A KP I     + +  Y ++  G L+ + G++I
Sbjct: 315  IQPGQKS--------------------AKKPEIA----MVIAPYTATGNGQLSLEPGNLI 208

Query: 1023 VVTKKD-GDWWTGTVG-----DKSGVFPSNYVR 1049
             V +K    WW G +       K G FP++YV+
Sbjct: 207  HVRQKSPRGWWEGELQARGQRKKIGWFPADYVK 109

 Score = 51.2 bits (121), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 23/73 (31%), Positives = 41/73 (56%)
 Frame = -2

Query: 1154 IGMYDYTAQNDDELAFSKGQIINVLNKEDPDWWKGEVSGQVGLFPSNYVKLTTDMDPSQQ 1213
            + MY Y +    +L F++G +I ++ K+D DWW G +  + G+FPS YVK   ++ P Q+
Sbjct: 471  VAMYSYVSGETADLTFNEGDMI-LVTKKDEDWWTGTLGEKTGMFPSTYVK-KVEIQPGQK 298

Query: 1214 WCSDLHLLDMLTP 1226
                  +  ++ P
Sbjct: 297  SAKKPEIAMVIAP 259

 Score = 39.7 bits (91), Expect = 0.010,   Method: Compositional matrix adjust.
 Identities = 19/56 (33%), Positives = 31/56 (55%)
 Frame = -2

Query: 742 YYRALYPFESRSHDEITIQPGDIVMVDESQTGEPGWLGGELKGKTGWFPANYAEKI 797
           YY A+Y + S    ++T   GD+++V +    +  W  G L  KTG FP+ Y +K+
Sbjct: 477 YYVAMYSYVSGETADLTFNEGDMILVTKK---DEDWWTGTLGEKTGMFPSTYVKKV 319

 Score = 38.9 bits (89), Expect = 0.020,   Method: Compositional matrix adjust.
 Identities = 23/82 (28%), Positives = 41/82 (50%), Gaps = 5/82 (6%)
 Frame = -2

Query: 746 LYPFESRSHDEITIQPGDIVMVDESQTGEPGWLGGELKG-----KTGWFPANYAEKIPEN 800
           + P+ +  + +++++PG+++ V   Q    GW  GEL+      K GWFPA+Y + +  +
Sbjct: 267 IAPYTATGNGQLSLEPGNLIHV--RQKSPRGWWEGELQARGQRKKIGWFPADYVKPLGSS 94

Query: 801 EVPTPAKPVTDLTSAPAPKLAL 822
                        S P PK+AL
Sbjct: 93  SA----------RSTPDPKVAL 58

 Score = 37.0 bits (84), Expect = 0.073,   Method: Compositional matrix adjust.
 Identities = 22/66 (33%), Positives = 34/66 (51%), Gaps = 6/66 (9%)
 Frame = -2

Query: 911 AQALYPWRAKKDNHLNFNKSDVITVLEQQDM-WWFGEVQ--GQK---GWFPKSYVKLISG 964
           A  + P+ A  +  L+    ++I V ++    WW GE+Q  GQ+   GWFP  YVK +  
Sbjct: 276 AMVIAPYTATGNGQLSLEPGNLIHVRQKSPRGWWEGELQARGQRKKIGWFPADYVKPLGS 97

Query: 965 PVRKST 970
              +ST
Sbjct: 96  SSARST 79
>30482
          Length = 610

 Score =  103 bits (256), Expect = 7e-22,   Method: Compositional matrix adjust.
 Identities = 84/243 (34%), Positives = 108/243 (44%), Gaps = 5/243 (2%)
 Frame = +3

Query: 704 SRLFHPHQEPAKLATQAPWSTTEKGPLTISAQESVKVVYYRALYPFESRSHDEITIQPGD 763
           S    P  +     T   W TT+      +    +K   YRAL+PFESRS DE+ I  GD
Sbjct: 24  SAFSSPATKSTTAGTADVWGTTDP----FAGGSGIKKTRYRALFPFESRSEDELNINTGD 191

Query: 764 IVMVDESQTGEPG---WLGGELK-GKTGWFPANYAEKIPENEVPTPAKPVTDLTSAPAPK 819
            + V +  + EPG   W  GE K GK GWFP  YAE  PE     PA P    +S PA  
Sbjct: 192 DIWVWDVPS-EPGMEEWFKGETKDGKVGWFPQAYAEPNPE-----PAAPA--FSSQPASS 347

Query: 820 LALRETPAPLPVTSSEPSTTPNNWADFSSTWPSSSNEKPETDNWDTWAAQPSLTVPSAGQ 879
                   P+  +++  S      AD                         S   PSA  
Sbjct: 348 DVFGSAFQPVQQSANVASAFSAGVAD-------------------------SFNTPSAPP 452

Query: 880 LRQRSAFTPATATGSSPSPVLGQGEKV-EGLQAQALYPWRAKKDNHLNFNKSDVITVLEQ 938
           + +           SS  P  G+  K  EGL+AQALY W+A++DNHL+FNK D+I V EQ
Sbjct: 453 IAE-----------SSFQPTPGESHKAPEGLKAQALYQWKARQDNHLSFNKDDIIVVKEQ 599

Query: 939 QDM 941
           +DM
Sbjct: 600 EDM 608

 Score = 38.5 bits (88), Expect = 0.024,   Method: Compositional matrix adjust.
 Identities = 40/173 (23%), Positives = 77/173 (44%), Gaps = 42/173 (24%)
 Frame = +3

Query: 898  PVLGQGEKVEGLQAQALYPWRAKKDNHLNFNKSDVITVLE-----QQDMWWFGEVQ-GQK 951
            P  G G  ++  + +AL+P+ ++ ++ LN N  D I V +       + W+ GE + G+ 
Sbjct: 93   PFAG-GSGIKKTRYRALFPFESRSEDELNINTGDDIWVWDVPSEPGMEEWFKGETKDGKV 269

Query: 952  GWFPKSYVKL-----------------ISG----PVRKSTSIDTGPTESPASLKRVASPA 990
            GWFP++Y +                  + G    PV++S ++ +    S        +P+
Sbjct: 270  GWFPQAYAEPNPEPAAPAFSSQPASSDVFGSAFQPVQQSANVAS--AFSAGVADSFNTPS 443

Query: 991  AKP-------AIPGEEFI--------AMYTYESSEQGDLTFQQGDVIVVTKKD 1028
            A P         PGE           A+Y +++ +   L+F + D+IVV +++
Sbjct: 444  APPIAESSFQPTPGESHKAPEGLKAQALYQWKARQDNHLSFNKDDIIVVKEQE 602
>19303
          Length = 676

 Score = 75.1 bits (183), Expect = 2e-13,   Method: Composition-based stats.
 Identities = 35/85 (41%), Positives = 57/85 (67%)
 Frame = -1

Query: 15  WAITVEERAKHDQQFLSLKPIAGFITGDQARNFFFQSGLPQPVLAQIWALADMNNDGRMD 74
           W ++  E+ ++D  F  L PI G ++G  A++   +S LP  VL+++W LAD++ DG +D
Sbjct: 415 WVVS-REKYEYDDSFSKLNPINGKVSGAAAKSEMVKSKLPNSVLSKVWKLADVDKDGMLD 239

Query: 75  QVEFSIAMKLIKLKLQGYQLPSTLP 99
             E+++A  LIK+KL+G+ LPS LP
Sbjct: 238 ADEWALANHLIKIKLEGHDLPSDLP 164

 Score = 57.4 bits (137), Expect = 5e-08,   Method: Composition-based stats.
 Identities = 28/80 (35%), Positives = 50/80 (62%)
 Frame = -1

Query: 214 EWAVPQSSRLKYRQLFNSHDKTMSGHLTGPQARTILMQSSLPQAQLASIWNLSDIDQDGK 273
           EW V +  + +Y   F S    ++G ++G  A++ +++S LP + L+ +W L+D+D+DG 
Sbjct: 418 EWVVSRE-KYEYDDSF-SKLNPINGKVSGAAAKSEMVKSKLPNSVLSKVWKLADVDKDGM 245

Query: 274 LTAEEFILAMHLIDVAMSGQ 293
           L A+E+ LA HLI + + G 
Sbjct: 244 LDADEWALANHLIKIKLEGH 185
>01130
          Length = 1032

 Score = 72.8 bits (177), Expect = 1e-12,   Method: Compositional matrix adjust.
 Identities = 38/100 (38%), Positives = 58/100 (58%)
 Frame = +3

Query: 16  AITVEERAKHDQQFLSLKPIAGFITGDQARNFFFQSGLPQPVLAQIWALADMNNDGRMDQ 75
            ++ EER  ++  F S  P+ G+I G+  R+ F +SGL   VL+QIW LAD++ND  ++ 
Sbjct: 216 VVSDEERQLYELLFYSQGPVDGYILGEGVRDLFLKSGLSLRVLSQIWNLADVSNDNVLNV 395

Query: 76  VEFSIAMKLIKLKLQGYQLPSTLPPVMKQQPVAISSAPAF 115
            EFS+ M LI+   +G + P TLP  +     A  + PA 
Sbjct: 396 HEFSLVMHLIRGLHKGLKAPPTLPRKLTPPKTAPLALPAI 515

 Score = 58.2 bits (139), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 30/82 (36%), Positives = 42/82 (51%)
 Frame = +3

Query: 211 PAAEWAVPQSSRLKYRQLFNSHDKTMSGHLTGPQARTILMQSSLPQAQLASIWNLSDIDQ 270
           P A  A+    R  Y +LF + D    G L G   R +   S L    L+ +WNLSD+ +
Sbjct: 495 PLALPAITPPEREAYIKLFRALDVQGKGFLDGDCCRHVFEASELTSDVLSDVWNLSDVTR 674

Query: 271 DGKLTAEEFILAMHLIDVAMSG 292
           DGKL  +EF +A HL+    +G
Sbjct: 675 DGKLDVDEFCVACHLLRFVKAG 740

 Score = 53.5 bits (127), Expect = 7e-07,   Method: Compositional matrix adjust.
 Identities = 29/78 (37%), Positives = 38/78 (48%), Gaps = 1/78 (1%)
 Frame = +3

Query: 210 PPAAEW-AVPQSSRLKYRQLFNSHDKTMSGHLTGPQARTILMQSSLPQAQLASIWNLSDI 268
           P   EW  V    R  Y  LF S    + G++ G   R + ++S L    L+ IWNL+D+
Sbjct: 195 PDGTEWPVVSDEERQLYELLFYSQG-PVDGYILGEGVRDLFLKSGLSLRVLSQIWNLADV 371

Query: 269 DQDGKLTAEEFILAMHLI 286
             D  L   EF L MHLI
Sbjct: 372 SNDNVLNVHEFSLVMHLI 425

 Score = 52.0 bits (123), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 31/89 (34%), Positives = 46/89 (51%), Gaps = 1/89 (1%)
 Frame = +3

Query: 7   PFGGSLDVWAITVEERAKHDQQFLSLKPIA-GFITGDQARNFFFQSGLPQPVLAQIWALA 65
           P    L + AIT  ER  + + F +L     GF+ GD  R+ F  S L   VL+ +W L+
Sbjct: 483 PKTAPLALPAITPPEREAYIKLFRALDVQGKGFLDGDCCRHVFEASELTSDVLSDVWNLS 662

Query: 66  DMNNDGRMDQVEFSIAMKLIKLKLQGYQL 94
           D+  DG++D  EF +A  L++    G  L
Sbjct: 663 DVTRDGKLDVDEFCVACHLLRFVKAGNSL 749
>12324
          Length = 946

 Score = 65.1 bits (157), Expect = 3e-10,   Method: Composition-based stats.
 Identities = 32/75 (42%), Positives = 47/75 (62%), Gaps = 1/75 (1%)
 Frame = +3

Query: 1130 SPGTSKITPTE-LPKTAVQPAVCQVIGMYDYTAQNDDELAFSKGQIINVLNKEDPDWWKG 1188
            + G   + P E +P T ++    +V+ +YDY A+ DDEL FS+  +I V+ K D  WW+G
Sbjct: 636  ATGPGFLGPDEYMPATYIE----KVVAIYDYEAEKDDELTFSENSVIYVIRKNDDGWWEG 803

Query: 1189 EVSGQVGLFPSNYVK 1203
             + G  GLFPSNYV+
Sbjct: 804  VMDGVTGLFPSNYVE 848

 Score = 53.1 bits (126), Expect = 9e-07,   Method: Composition-based stats.
 Identities = 25/57 (43%), Positives = 37/57 (64%), Gaps = 1/57 (1%)
 Frame = +3

Query: 993  PAIPGEEFIAMYTYESSEQGDLTFQQGDVIVVTKKDGD-WWTGTVGDKSGVFPSNYV 1048
            PA   E+ +A+Y YE+ +  +LTF +  VI V +K+ D WW G +   +G+FPSNYV
Sbjct: 675  PATYIEKVVAIYDYEAEKDDELTFSENSVIYVIRKNDDGWWEGVMDGVTGLFPSNYV 845

 Score = 42.7 bits (99), Expect = 0.001,   Method: Composition-based stats.
 Identities = 20/49 (40%), Positives = 32/49 (65%), Gaps = 1/49 (2%)
 Frame = +3

Query: 913 ALYPWRAKKDNHLNFNKSDVITVLEQQD-MWWFGEVQGQKGWFPKSYVK 960
           A+Y + A+KD+ L F+++ VI V+ + D  WW G + G  G FP +YV+
Sbjct: 702 AIYDYEAEKDDELTFSENSVIYVIRKNDDGWWEGVMDGVTGLFPSNYVE 848

 Score = 40.8 bits (94), Expect = 0.004,   Method: Composition-based stats.
 Identities = 29/102 (28%), Positives = 45/102 (44%), Gaps = 3/102 (2%)
 Frame = +3

Query: 697 PEMQDKQSRLFHPHQEPAKLATQAPWSTTEKGPLTISAQESVKVVYYR---ALYPFESRS 753
           PE  D      +P   P     + P++ T  GP  +   E +   Y     A+Y +E+  
Sbjct: 567 PEFSDHGDGDSNPPAAPP----EDPYAAT--GPGFLGPDEYMPATYIEKVVAIYDYEAEK 728

Query: 754 HDEITIQPGDIVMVDESQTGEPGWLGGELKGKTGWFPANYAE 795
            DE+T     ++ V   +  + GW  G + G TG FP+NY E
Sbjct: 729 DDELTFSENSVIYV--IRKNDDGWWEGVMDGVTGLFPSNYVE 848

 Score = 38.1 bits (87), Expect = 0.030,   Method: Composition-based stats.
 Identities = 19/53 (35%), Positives = 28/53 (52%)
 Frame = +3

Query: 1075 IASYAATGPEQLTLAPGQLILIRKKNPGGWWEGELQARGKKRQIGWFPANYVK 1127
            I  Y A   ++LT +   +I + +KN  GWWEG +         G FP+NYV+
Sbjct: 705  IYDYEAEKDDELTFSENSVIYVIRKNDDGWWEGVMDG-----VTGLFPSNYVE 848
>16716
          Length = 934

 Score = 60.5 bits (145), Expect = 6e-09,   Method: Compositional matrix adjust.
 Identities = 24/52 (46%), Positives = 32/52 (61%)
 Frame = -1

Query: 1153 VIGMYDYTAQNDDELAFSKGQIINVLNKEDPDWWKGEVSGQVGLFPSNYVKL 1204
             I +YDY A +DDEL F    +I  +   D  WW+G   G+ GLFP+NYV+L
Sbjct: 463  AIALYDYQAADDDELTFDPDDVITDIEMIDDGWWRGSCHGKNGLFPANYVEL 308

 Score = 57.4 bits (137), Expect = 5e-08,   Method: Compositional matrix adjust.
 Identities = 30/79 (37%), Positives = 45/79 (56%), Gaps = 3/79 (3%)
 Frame = -1

Query: 976  PTESPASL--KRVASPAAKPAIPGEEFIAMYTYESSEQGDLTFQQGDVIV-VTKKDGDWW 1032
            P ESP  +  +  A+PA      G   IA+Y Y++++  +LTF   DVI  +   D  WW
Sbjct: 541  PEESPYEMADEEPAAPAQSQPGGGSTAIALYDYQAADDDELTFDPDDVITDIEMIDDGWW 362

Query: 1033 TGTVGDKSGVFPSNYVRLK 1051
             G+   K+G+FP+NYV L+
Sbjct: 361  RGSCHGKNGLFPANYVELQ 305

 Score = 52.4 bits (124), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 25/55 (45%), Positives = 33/55 (60%), Gaps = 1/55 (1%)
 Frame = -1

Query: 908 GLQAQALYPWRAKKDNHLNFNKSDVITVLEQ-QDMWWFGEVQGQKGWFPKSYVKL 961
           G  A ALY ++A  D+ L F+  DVIT +E   D WW G   G+ G FP +YV+L
Sbjct: 472 GSTAIALYDYQAADDDELTFDPDDVITDIEMIDDGWWRGSCHGKNGLFPANYVEL 308

 Score = 36.6 bits (83), Expect = 0.098,   Method: Compositional matrix adjust.
 Identities = 18/55 (32%), Positives = 25/55 (45%)
 Frame = -1

Query: 1074 VIASYAATGPEQLTLAPGQLILIRKKNPGGWWEGELQARGKKRQIGWFPANYVKL 1128
             +  Y A   ++LT  P  +I   +    GWW G    +      G FPANYV+L
Sbjct: 457  ALYDYQAADDDELTFDPDDVITDIEMIDDGWWRGSCHGKN-----GLFPANYVEL 308
>36305
          Length = 586

 Score = 57.0 bits (136), Expect = 6e-08,   Method: Composition-based stats.
 Identities = 27/71 (38%), Positives = 45/71 (63%)
 Frame = -1

Query: 1608 GKSNPYCEVTMGSQCHITKTIQDTLNPKWNSNCQFFIRDLEQEVLCITVFERDQFSPDDF 1667
            GKS+PY  VT+G+Q   TK I DT+ P+WN   +F I + + ++L + + ++D  + DD 
Sbjct: 583  GKSDPYTVVTVGAQTFKTKVIDDTVEPRWNEVFEFVIDERDGQILKLNISDKDPGNKDDP 404

Query: 1668 LGRTEIRVADI 1678
            LG T + ++ I
Sbjct: 403  LGSTTMDISTI 371
>17286
          Length = 489

 Score = 53.9 bits (128), Expect = 6e-07,   Method: Composition-based stats.
 Identities = 20/50 (40%), Positives = 36/50 (72%)
 Frame = +3

Query: 1155 GMYDYTAQNDDELAFSKGQIINVLNKEDPDWWKGEVSGQVGLFPSNYVKL 1204
             +YD+  ++D EL F +G +I ++++ D +W++G V G+VG FP NYV++
Sbjct: 36   AIYDFLPESDGELGFQEGDMITLISQVDENWFEGSVHGKVGYFPINYVEV 185

 Score = 47.0 bits (110), Expect = 7e-05,   Method: Composition-based stats.
 Identities = 21/53 (39%), Positives = 35/53 (66%), Gaps = 1/53 (1%)
 Frame = +3

Query: 911 AQALYPWRAKKDNHLNFNKSDVITVLEQQDMWWF-GEVQGQKGWFPKSYVKLI 962
           A+A+Y +  + D  L F + D+IT++ Q D  WF G V G+ G+FP +YV+++
Sbjct: 30  ARAIYDFLPESDGELGFQEGDMITLISQVDENWFEGSVHGKVGYFPINYVEVV 188

 Score = 45.1 bits (105), Expect = 3e-04,   Method: Composition-based stats.
 Identities = 20/50 (40%), Positives = 33/50 (66%), Gaps = 1/50 (2%)
 Frame = +3

Query: 1002 AMYTYESSEQGDLTFQQGDVI-VVTKKDGDWWTGTVGDKSGVFPSNYVRL 1050
            A+Y +     G+L FQ+GD+I ++++ D +W+ G+V  K G FP NYV +
Sbjct: 36   AIYDFLPESDGELGFQEGDMITLISQVDENWFEGSVHGKVGYFPINYVEV 185

 Score = 42.0 bits (97), Expect = 0.002,   Method: Composition-based stats.
 Identities = 25/61 (40%), Positives = 34/61 (55%), Gaps = 1/61 (1%)
 Frame = +3

Query: 744 RALYPFESRSHDEITIQPGDIVMVDESQTGEPGWLGGELKGKTGWFPANYAE-KIPENEV 802
           RA+Y F   S  E+  Q GD++ +  SQ  E  W  G + GK G+FP NY E  +P + V
Sbjct: 33  RAIYDFLPESDGELGFQEGDMITLI-SQVDE-NWFEGSVHGKVGYFPINYVEVVVPIS*V 206

Query: 803 P 803
           P
Sbjct: 207 P 209

 Score = 32.3 bits (72), Expect = 1.6,   Method: Composition-based stats.
 Identities = 17/66 (25%), Positives = 31/66 (46%)
 Frame = +3

Query: 1066 GKKPEIAQVIASYAATGPEQLTLAPGQLILIRKKNPGGWWEGELQARGKKRQIGWFPANY 1125
            G K   A+ I  +      +L    G +I +  +    W+EG +  +     +G+FP NY
Sbjct: 12   GVKQPCARAIYDFLPESDGELGFQEGDMITLISQVDENWFEGSVHGK-----VGYFPINY 176

Query: 1126 VKLLSP 1131
            V+++ P
Sbjct: 177  VEVVVP 194
>01494
          Length = 2122

 Score = 53.5 bits (127), Expect = 8e-07,   Method: Compositional matrix adjust.
 Identities = 22/53 (41%), Positives = 35/53 (66%), Gaps = 1/53 (1%)
 Frame = +3

Query: 1152 QVIGMYDYTAQNDDELAFSKGQIINVLNKEDPDWWKGEVSGQV-GLFPSNYVK 1203
            +V  ++DY A  DDEL+F KG II  ++++D  WW+G+   +    FPSN+V+
Sbjct: 309  RVKALHDYNANRDDELSFCKGAIITNVSRQDGGWWRGDYGAKKQHWFPSNFVE 467

 Score = 42.4 bits (98), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 19/49 (38%), Positives = 31/49 (63%), Gaps = 2/49 (4%)
 Frame = +3

Query: 1002 AMYTYESSEQGDLTFQQGDVIV-VTKKDGDWWTGTVG-DKSGVFPSNYV 1048
            A++ Y ++   +L+F +G +I  V+++DG WW G  G  K   FPSN+V
Sbjct: 318  ALHDYNANRDDELSFCKGAIITNVSRQDGGWWRGDYGAKKQHWFPSNFV 464

 Score = 40.8 bits (94), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 26/99 (26%), Positives = 47/99 (47%), Gaps = 1/99 (1%)
 Frame = +3

Query: 1072 AQVIASYAATGPEQLTLAPGQLILIRKKNPGGWWEGELQARGKKRQIGWFPANYVKLLSP 1131
             + +  Y A   ++L+   G +I    +  GGWW G+    G K+Q  WFP+N+V+ +  
Sbjct: 312  VKALHDYNANRDDELSFCKGAIITNVSRQDGGWWRGDY---GAKKQ-HWFPSNFVEEIE- 476

Query: 1132 GTSKITPTELPKTAVQPAVCQVIG-MYDYTAQNDDELAF 1169
              S +    +P  ++Q     + G + +  A   D+ AF
Sbjct: 477  THSDVNSDSMPLGSLQQGSFDIQGCLVEPLAPRGDKSAF 593

 Score = 40.8 bits (94), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 24/78 (30%), Positives = 38/78 (48%), Gaps = 6/78 (7%)
 Frame = +1

Query: 1608 GKSNPYCEVTM-GSQCHITK-----TIQDTLNPKWNSNCQFFIRDLEQEVLCITVFERDQ 1661
            G ++P+ E+ + G +C   K      + + LNP WN NC F +   E  +L   V + D 
Sbjct: 1213 GIASPFVEIEVTGXECDNQKFKTGTRVDNGLNPVWNENCVFDVLCPEMALLRFAVMDEDI 1392

Query: 1662 FSPDDFLGRTEIRVADIK 1679
            F   +FLG+    V  I+
Sbjct: 1393 FGDPNFLGQAXFPVPCIR 1446

 Score = 35.4 bits (80), Expect = 0.20,   Method: Compositional matrix adjust.
 Identities = 21/71 (29%), Positives = 37/71 (52%), Gaps = 2/71 (2%)
 Frame = +3

Query: 744 RALYPFESRSHDEITIQPGDIVMVDESQTGEPGWLGGELKGKT-GWFPANYAEKI-PENE 801
           +AL+ + +   DE++   G I+     Q G  GW  G+   K   WFP+N+ E+I   ++
Sbjct: 315 KALHDYNANRDDELSFCKGAIITNVSRQDG--GWWRGDYGAKKQHWFPSNFVEEIETHSD 488

Query: 802 VPTPAKPVTDL 812
           V + + P+  L
Sbjct: 489 VNSDSMPLGSL 521
>29687
          Length = 434

 Score = 51.2 bits (121), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 25/64 (39%), Positives = 42/64 (65%), Gaps = 2/64 (3%)
 Frame = -2

Query: 1152 QVIGMYDYTAQNDDELAFSKGQIINVLNKEDPDWWKGEV-SGQVGLFPSNYV-KLTTDMD 1209
            +V  ++DY A+ +DEL+F KG II  ++++D  WW+G+  + +   FPSNYV ++ T  D
Sbjct: 295  RVKALHDYNAKREDELSFCKGAIITNVSRQDGGWWRGDYGTKKQHWFPSNYVEEIDTQTD 116

Query: 1210 PSQQ 1213
             S +
Sbjct: 115  SSNE 104

 Score = 42.4 bits (98), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 21/55 (38%), Positives = 34/55 (61%), Gaps = 2/55 (3%)
 Frame = -2

Query: 1002 AMYTYESSEQGDLTFQQGDVIV-VTKKDGDWWTGTVGDKS-GVFPSNYVRLKDSE 1054
            A++ Y +  + +L+F +G +I  V+++DG WW G  G K    FPSNYV   D++
Sbjct: 286  ALHDYNAKREDELSFCKGAIITNVSRQDGGWWRGDYGTKKQHWFPSNYVEEIDTQ 122

 Score = 41.2 bits (95), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 19/56 (33%), Positives = 30/56 (53%)
 Frame = -2

Query: 1072 AQVIASYAATGPEQLTLAPGQLILIRKKNPGGWWEGELQARGKKRQIGWFPANYVK 1127
             + +  Y A   ++L+   G +I    +  GGWW G+    G K+Q  WFP+NYV+
Sbjct: 292  VKALHDYNAKREDELSFCKGAIITNVSRQDGGWWRGDY---GTKKQ-HWFPSNYVE 137

 Score = 37.0 bits (84), Expect = 0.074,   Method: Compositional matrix adjust.
 Identities = 21/69 (30%), Positives = 35/69 (50%), Gaps = 1/69 (1%)
 Frame = -2

Query: 730 LTISAQESVKVVYYRALYPFESRSHDEITIQPGDIVMVDESQTGEPGWLGGELKGKT-GW 788
           L I+  +    +  +AL+ + ++  DE++   G I+     Q G  GW  G+   K   W
Sbjct: 331 LYINPNDFTTKLRVKALHDYNAKREDELSFCKGAIITNVSRQDG--GWWRGDYGTKKQHW 158

Query: 789 FPANYAEKI 797
           FP+NY E+I
Sbjct: 157 FPSNYVEEI 131
>32146
          Length = 715

 Score = 49.7 bits (117), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 38/145 (26%), Positives = 66/145 (45%), Gaps = 27/145 (18%)
 Frame = +2

Query: 1454 RKFLHSGKLYKAKSNK--ELYGFLFNDFLLLTQITK---------------PLGSSGTDK 1496
            R+ LH G L   +S K  ++Y FLF+D LL+T+I K               P G  GT  
Sbjct: 77   RQLLHEGPLTLMESPKPIDVYAFLFDDMLLITKIKKSARKQKQGLESALRSPHGGDGTS- 253

Query: 1497 VFSPKSNLQYKMYKTPIFLNE-VLVKLPT---DPSGDEPIFHISHIDR------VYTLRA 1546
                     Y +++ P+ ++  +L  +P      +G + +F + H+ R      ++TL+ 
Sbjct: 254  ---------YVVFRQPLAMDRFILHDIPASDLSANGLKQVFVLVHLSRFQQILGIFTLQT 406

Query: 1547 ESINERTAWVQKIKAASELYIETEK 1571
             S   +  W+  I+ A E Y E ++
Sbjct: 407  SSDTAKGTWLTAIREAQERYAEKQQ 481
>18372
          Length = 468

 Score = 48.5 bits (114), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 29/96 (30%), Positives = 48/96 (50%)
 Frame = +2

Query: 1308 IGDILSAQLPHMQPYIRFCSCQLNGAALIQQKTDEAPDFKEFVKRLAMDPRCKGMPLSSF 1367
            +G     +    Q Y  +C  +    AL  +  D  P FK+  +RL        +PL ++
Sbjct: 38   VGRCFVNRKEEFQMYSTYCQNKPKSEALRMRVGDSNPFFKDCQQRLG-----HKLPLGAY 202

Query: 1368 ILKPMQRVTRYPLIIKNILENTPENHPDHSHLKHAL 1403
            +LKP+QR+T+Y L++K +L  T E+      L+ AL
Sbjct: 203  LLKPVQRITKYQLLLKEMLRFTGEDEDLERQLQDAL 310
>11641
          Length = 2509

 Score = 48.1 bits (113), Expect = 3e-05,   Method: Composition-based stats.
 Identities = 22/88 (25%), Positives = 49/88 (55%), Gaps = 2/88 (2%)
 Frame = -1

Query: 1336 IQQKTDEAPDFKEF--VKRLAMDPRCKGMPLSSFILKPMQRVTRYPLIIKNILENTPENH 1393
            +  K  E P+  ++   K   M  R     + + ++KP+QR+ +YPL++  + ++T ++H
Sbjct: 2461 VMDKYHELPEACQYFAAKVEEMRRRTNIFDVEAMLIKPVQRILKYPLLLNELFKSTEDDH 2282

Query: 1394 PDHSHLKHALEKAEELCSQVNEGVREKE 1421
            PD + + +A+    ++ + +NE  R K+
Sbjct: 2281 PDKTAIGNAIRAMTDVATAINEYKRRKD 2198

 Score = 41.6 bits (96), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 23/67 (34%), Positives = 38/67 (56%), Gaps = 2/67 (2%)
 Frame = -1

Query: 733 SAQESVKVVYYRALYPFESRSHDEITIQPGDIVMVDESQ--TGEPGWLGGELKGKTGWFP 790
           SA+ + +  YY A +PF++RS +E+T+  G +V+V   Q   G   W   +  G  G+ P
Sbjct: 859 SAEPASQHEYYCADFPFQARSSNEVTLFAGQVVVVLNRQDLDGNTEWWLVDADGYQGYAP 680

Query: 791 ANYAEKI 797
           A+Y  K+
Sbjct: 679 ASYLRKM 659

 Score = 36.2 bits (82), Expect = 0.11,   Method: Compositional matrix adjust.
 Identities = 15/51 (29%), Positives = 30/51 (58%), Gaps = 4/51 (7%)
 Frame = -1

Query: 1157 YDYTAQNDDELAFSKGQIINVLNKEDPD----WWKGEVSGQVGLFPSNYVK 1203
            + + A++ +E+    GQ++ VLN++D D    WW  +  G  G  P++Y++
Sbjct: 817  FPFQARSSNEVTLFAGQVVVVLNRQDLDGNTEWWLVDADGYQGYAPASYLR 665
>26032
          Length = 465

 Score = 47.4 bits (111), Expect = 5e-05,   Method: Composition-based stats.
 Identities = 26/74 (35%), Positives = 42/74 (56%), Gaps = 3/74 (4%)
 Frame = +2

Query: 922 DNHLNFNKSDVITVLEQQD-MWWFGEVQGQKGWFPKSYVKLISGPVRK-STSIDTGPTES 979
           D+ L F K+D+IT++ Q+D   W GE+ G +GWFP  +V+++    +  S++ D    E+
Sbjct: 47  DDELGFRKNDIITLISQKDEHCWIGELNGLRGWFPAKFVEVLDERSKNYSSAGDDAVNET 226

Query: 980 PASLKR-VASPAAK 992
              L R    PA K
Sbjct: 227 VTDLVRGTLCPALK 268

 Score = 45.4 bits (106), Expect = 2e-04,   Method: Composition-based stats.
 Identities = 18/47 (38%), Positives = 31/47 (65%)
 Frame = +2

Query: 1158 DYTAQNDDELAFSKGQIINVLNKEDPDWWKGEVSGQVGLFPSNYVKL 1204
            D+   +DDEL F K  II +++++D   W GE++G  G FP+ +V++
Sbjct: 29   DFERHDDDELGFRKNDIITLISQKDEHCWIGELNGLRGWFPAKFVEV 169

 Score = 39.7 bits (91), Expect = 0.012,   Method: Composition-based stats.
 Identities = 21/51 (41%), Positives = 28/51 (54%)
 Frame = +2

Query: 749 FESRSHDEITIQPGDIVMVDESQTGEPGWLGGELKGKTGWFPANYAEKIPE 799
           FE    DE+  +  DI+ +  SQ  E  W+G EL G  GWFPA + E + E
Sbjct: 32  FERHDDDELGFRKNDIITLI-SQKDEHCWIG-ELNGLRGWFPAKFVEVLDE 178

 Score = 33.1 bits (74), Expect = 1.1,   Method: Composition-based stats.
 Identities = 17/58 (29%), Positives = 33/58 (56%), Gaps = 3/58 (5%)
 Frame = +2

Query: 1006 YESSEQGDLTFQQGDVI-VVTKKDGDWWTGTVGDKSGVFPSNYVRLKD--SEGSGTAG 1060
            +E  +  +L F++ D+I ++++KD   W G +    G FP+ +V + D  S+   +AG
Sbjct: 32   FERHDDDELGFRKNDIITLISQKDEHCWIGELNGLRGWFPAKFVEVLDERSKNYSSAG 205
>13664
          Length = 507

 Score = 46.2 bits (108), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 20/46 (43%), Positives = 28/46 (60%), Gaps = 1/46 (2%)
 Frame = +2

Query: 1152 QVIGMYDYTAQNDDELAFSKGQIINVLNKEDPDWWKGE-VSGQVGL 1196
            +V+ +YDY AQ  DEL    G +I +L+K+   WW GE + GQ G 
Sbjct: 368  KVVALYDYKAQRSDELTILSGDVIMLLHKDSESWWMGELLDGQQGF 505

 Score = 35.0 bits (79), Expect = 0.28,   Method: Compositional matrix adjust.
 Identities = 25/78 (32%), Positives = 41/78 (52%)
 Frame = +2

Query: 711 QEPAKLATQAPWSTTEKGPLTISAQESVKVVYYRALYPFESRSHDEITIQPGDIVMVDES 770
           Q  A+ + Q+P  +T K           KVV   ALY ++++  DE+TI  GD++M+   
Sbjct: 311 QGKAQFSFQSPLGSTRK---------PKKVV---ALYDYKAQRSDELTILSGDVIMLLHK 454

Query: 771 QTGEPGWLGGELKGKTGW 788
            + E  W+G  L G+ G+
Sbjct: 455 DS-ESWWMGELLDGQQGF 505

 Score = 34.3 bits (77), Expect = 0.42,   Method: Compositional matrix adjust.
 Identities = 34/136 (25%), Positives = 57/136 (41%), Gaps = 5/136 (3%)
 Frame = +2

Query: 979  SPASLKRVASPAAKPAIPGEEFIAMYTY-ESSEQGDLTFQQGDVIVVTKKDGDWWTGTVG 1037
            SPA+L   A+P     I  ++F +   Y + S+    +F +               G  G
Sbjct: 119  SPAALSPHATPTLLSTIQQQQFTSHNMYMKQSDSWRPSFSE--------------VGRHG 256

Query: 1038 DKSGVFPSN--YVRLKDSEGSGTAGKTGSLG--KKPEIAQVIASYAATGPEQLTLAPGQL 1093
             KS  +      + L +S+G         LG  +KP+    +  Y A   ++LT+  G +
Sbjct: 257  GKSSAYFGRPPQIALDNSQGKAQFSFQSPLGSTRKPKKVVALYDYKAQRSDELTILSGDV 436

Query: 1094 ILIRKKNPGGWWEGEL 1109
            I++  K+   WW GEL
Sbjct: 437  IMLLHKDSESWWMGEL 484

 Score = 33.5 bits (75), Expect = 0.79,   Method: Compositional matrix adjust.
 Identities = 16/43 (37%), Positives = 27/43 (62%), Gaps = 2/43 (4%)
 Frame = +2

Query: 913 ALYPWRAKKDNHLNFNKSDVITVLEQ-QDMWWFGE-VQGQKGW 953
           ALY ++A++ + L     DVI +L +  + WW GE + GQ+G+
Sbjct: 377 ALYDYKAQRSDELTILSGDVIMLLHKDSESWWMGELLDGQQGF 505
>33143
          Length = 1469

 Score = 45.4 bits (106), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 21/72 (29%), Positives = 36/72 (50%), Gaps = 3/72 (4%)
 Frame = -2

Query: 1148 PAVCQVIGMYDYTAQNDDELAFSKGQIINVLN---KEDPDWWKGEVSGQVGLFPSNYVKL 1204
            PA+     +  Y A   DE++   G  ++V++    E   WW+G+   +VG FP++ V++
Sbjct: 445  PAIAAAHAVKPYAAHASDEISLQVGDFVSVIDMPSSEGTKWWRGKKGFEVGFFPADCVEV 266

Query: 1205 TTDMDPSQQWCS 1216
              D  P   W S
Sbjct: 265  IRDKVPVSMWVS 230

 Score = 37.0 bits (84), Expect = 0.061,   Method: Compositional matrix adjust.
 Identities = 21/92 (22%), Positives = 45/92 (48%), Gaps = 17/92 (18%)
 Frame = -2

Query: 911 AQALYPWRAKKDNHLNFNKSDVITVLE----QQDMWWFGEVQGQKGWFPKSYVKLI---- 962
           A A+ P+ A   + ++    D ++V++    +   WW G+   + G+FP   V++I    
Sbjct: 430 AHAVKPYAAHASDEISLQVGDFVSVIDMPSSEGTKWWRGKKGFEVGFFPADCVEVIRDKV 251

Query: 963 ---------SGPVRKSTSIDTGPTESPASLKR 985
                    +GP+  S+++ T P  +PA+ ++
Sbjct: 250 PVSMWVSGVTGPLSISSTLATLPLSTPATARK 155

 Score = 32.3 bits (72), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 29/106 (27%), Positives = 45/106 (42%), Gaps = 7/106 (6%)
 Frame = -2

Query: 993  PAIPGEEFIAMYTYESSEQGDLTFQQGDVIVV----TKKDGDWWTGTVGDKSGVFPSNYV 1048
            PAI     +  Y   +S++  ++ Q GD + V    + +   WW G  G + G FP++ V
Sbjct: 445  PAIAAAHAVKPYAAHASDE--ISLQVGDFVSVIDMPSSEGTKWWRGKKGFEVGFFPADCV 272

Query: 1049 ---RLKDSEGSGTAGKTGSLGKKPEIAQVIASYAATGPEQLTLAPG 1091
               R K       +G TG L     +A +  S  AT  + L    G
Sbjct: 271  EVIRDKVPVSMWVSGVTGPLSISSTLATLPLSTPATARKPLVRKXG 134
>19469
          Length = 428

 Score = 45.1 bits (105), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 33/114 (28%), Positives = 54/114 (47%), Gaps = 10/114 (8%)
 Frame = -1

Query: 911  AQALYPWRAKKDNHLNFNKSDVITVLEQQ----DMWWFGEVQGQKGWFPKSYVKLISGPV 966
            A+ALY   A+  + L F + DVIT+LEQ     D WW   ++G++G  P + +K++SG +
Sbjct: 359  AKALYDNIAETPDELAFRRGDVITILEQDTAGLDGWWLCSLRGRQGIAPGNRLKILSGMI 180

Query: 967  RK------STSIDTGPTESPASLKRVASPAAKPAIPGEEFIAMYTYESSEQGDL 1014
                     T  D   TE  +  K  +     P   G+ ++  +   S E  D+
Sbjct: 179  EGMGKSSLQTEHDAAKTEWRSMEKSPSQVLVTPVKKGDVYLYDHPNHSMEDYDV 18

 Score = 42.4 bits (98), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 19/57 (33%), Positives = 32/57 (56%), Gaps = 3/57 (5%)
 Frame = -1

Query: 1155 GMYDYTAQNDDELAFSKGQIINVLNKEDP---DWWKGEVSGQVGLFPSNYVKLTTDM 1208
             +YD  A+  DELAF +G +I +L ++      WW   + G+ G+ P N +K+ + M
Sbjct: 353  ALYDNIAETPDELAFRRGDVITILEQDTAGLDGWWLCSLRGRQGIAPGNRLKILSGM 183

 Score = 33.1 bits (74), Expect = 1.0,   Method: Compositional matrix adjust.
 Identities = 24/93 (25%), Positives = 41/93 (44%), Gaps = 4/93 (4%)
 Frame = -1

Query: 1002 AMYTYESSEQGDLTFQQGDVIVVTKKD----GDWWTGTVGDKSGVFPSNYVRLKDSEGSG 1057
            A+Y   +    +L F++GDVI + ++D      WW  ++  + G+ P N  RLK   G  
Sbjct: 353  ALYDNIAETPDELAFRRGDVITILEQDTAGLDGWWLCSLRGRQGIAPGN--RLKILSGMI 180

Query: 1058 TAGKTGSLGKKPEIAQVIASYAATGPEQLTLAP 1090
                  SL  + + A+         P Q+ + P
Sbjct: 179  EGMGKSSLQTEHDAAKTEWRSMEKSPSQVLVTP 81

 Score = 32.7 bits (73), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 18/55 (32%), Positives = 29/55 (52%), Gaps = 1/55 (1%)
 Frame = -1

Query: 739 KVVYYRALYPFESRSHDEITIQPGDIVMVDESQT-GEPGWLGGELKGKTGWFPAN 792
           +V   +ALY   + + DE+  + GD++ + E  T G  GW    L+G+ G  P N
Sbjct: 371 QVFLAKALYDNIAETPDELAFRRGDVITILEQDTAGLDGWWLCSLRGRQGIAPGN 207
>18050
          Length = 448

 Score = 43.1 bits (100), Expect = 0.001,   Method: Composition-based stats.
 Identities = 23/60 (38%), Positives = 36/60 (60%), Gaps = 2/60 (3%)
 Frame = +3

Query: 1073 QVIA--SYAATGPEQLTLAPGQLILIRKKNPGGWWEGELQARGKKRQIGWFPANYVKLLS 1130
            QVIA  SY +  P+ L L  G ++ + +K P GW++GE   R +   +GWFP +Y + L+
Sbjct: 21   QVIAKHSYESDEPDVLQLELGDVVNVSRKLPDGWYQGE---RIRDGAVGWFPGSYTEELN 191

 Score = 35.8 bits (81), Expect = 0.14,   Method: Composition-based stats.
 Identities = 19/54 (35%), Positives = 27/54 (50%), Gaps = 2/54 (3%)
 Frame = +3

Query: 1152 QVIGMYDYTAQNDDELAFSKGQIINVLNKEDPDWWKGE--VSGQVGLFPSNYVK 1203
            QVI  + Y +   D L    G ++NV  K    W++GE    G VG FP +Y +
Sbjct: 21   QVIAKHSYESDEPDVLQLELGDVVNVSRKLPDGWYQGERIRDGAVGWFPGSYTE 182

 Score = 35.0 bits (79), Expect = 0.29,   Method: Composition-based stats.
 Identities = 20/55 (36%), Positives = 30/55 (54%), Gaps = 2/55 (3%)
 Frame = +3

Query: 745 ALYPFESRSHDEITIQPGDIVMVDESQTGEPGWLGGEL--KGKTGWFPANYAEKI 797
           A + +ES   D + ++ GD+V V  S+    GW  GE    G  GWFP +Y E++
Sbjct: 30  AKHSYESDEPDVLQLELGDVVNV--SRKLPDGWYQGERIRDGAVGWFPGSYTEEL 188

 Score = 30.4 bits (67), Expect = 6.1,   Method: Composition-based stats.
 Identities = 20/52 (38%), Positives = 31/52 (59%), Gaps = 3/52 (5%)
 Frame = +3

Query: 999  EFIAMYTYESSEQGDLTFQQGDVIVVTKKDGD-WWTGT-VGDKS-GVFPSNY 1047
            + IA ++YES E   L  + GDV+ V++K  D W+ G  + D + G FP +Y
Sbjct: 21   QVIAKHSYESDEPDVLQLELGDVVNVSRKLPDGWYQGERIRDGAVGWFPGSY 176
>30740
          Length = 488

 Score = 42.0 bits (97), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 18/54 (33%), Positives = 38/54 (70%), Gaps = 2/54 (3%)
 Frame = +2

Query: 1144 TAVQPAVCQ-VIGMYDYTAQNDDELAFSKGQIINVLNKEDPDWWKG-EVSGQVG 1195
            T ++PA  + ++G YD++ ++ ++L FSKG I+ +++K++ +WW   +  G+VG
Sbjct: 161  TLIRPAPREKLMGKYDFSGRDPEDLPFSKGDILELISKDEEEWWTARDKHGRVG 322
>28095
          Length = 597

 Score = 42.0 bits (97), Expect = 0.002,   Method: Composition-based stats.
 Identities = 19/56 (33%), Positives = 33/56 (58%), Gaps = 2/56 (3%)
 Frame = +3

Query: 744 RALYPFESRSHDEITIQPGDIVMVDESQTGEPGWLGG--ELKGKTGWFPANYAEKI 797
           +A+Y +++   DE++   GD ++  E Q  + GW+ G  E  G+ G  P+NY E+I
Sbjct: 267 KAMYDYQAADSDEVSFNDGDTII--ECQPVDAGWMTGRVERTGQYGMLPSNYVERI 428

 Score = 35.8 bits (81), Expect = 0.16,   Method: Composition-based stats.
 Identities = 19/62 (30%), Positives = 33/62 (53%), Gaps = 3/62 (4%)
 Frame = +3

Query: 905 KVEGLQAQALYPWRAKKDNHLNFNKSDVITVLEQQDMWWF-GEVQ--GQKGWFPKSYVKL 961
           +  G+  +A+Y ++A   + ++FN  D I   +  D  W  G V+  GQ G  P +YV+ 
Sbjct: 246 RSRGMVCKAMYDYQAADSDEVSFNDGDTIIECQPVDAGWMTGRVERTGQYGMLPSNYVER 425

Query: 962 IS 963
           I+
Sbjct: 426 IN 431
>17768
          Length = 492

 Score = 40.8 bits (94), Expect = 0.005,   Method: Composition-based stats.
 Identities = 19/78 (24%), Positives = 41/78 (52%)
 Frame = -1

Query: 1338 QKTDEAPDFKEFVKRLAMDPRCKGMPLSSFILKPMQRVTRYPLIIKNILENTPENHPDHS 1397
            +K  +  +F EF +    D RCK + L+  ++ P+Q  T+ PL++ N+ + T EN  +  
Sbjct: 234  EKLRQNSEFAEFERWCEQDARCKRLQLTDLLVAPIQHCTKLPLLLANVAKYT-ENKTERC 58

Query: 1398 HLKHALEKAEELCSQVNE 1415
             +  +++  +    Q+ +
Sbjct: 57   LVTESIDSVKTSLQQLED 4
>15115
          Length = 443

 Score = 40.0 bits (92), Expect = 0.008,   Method: Composition-based stats.
 Identities = 18/47 (38%), Positives = 28/47 (59%), Gaps = 1/47 (2%)
 Frame = -2

Query: 1159 YTAQNDDELAFSKGQIINVLNKEDPDWWKG-EVSGQVGLFPSNYVKL 1204
            + A +D E+ F    II  +++ D  WW+G    G  G+FP+NYV+L
Sbjct: 433  HQAGDDTEITFDPDDIITNIDQIDEGWWQGFAPDGSYGMFPANYVEL 293

 Score = 35.4 bits (80), Expect = 0.19,   Method: Composition-based stats.
 Identities = 17/47 (36%), Positives = 28/47 (59%), Gaps = 2/47 (4%)
 Frame = -2

Query: 1006 YESSEQGDLTFQQGDVIV-VTKKDGDWWTGTVGDKS-GVFPSNYVRL 1050
            +++ +  ++TF   D+I  + + D  WW G   D S G+FP+NYV L
Sbjct: 433  HQAGDDTEITFDPDDIITNIDQIDEGWWQGFAPDGSYGMFPANYVEL 293

 Score = 32.7 bits (73), Expect = 1.3,   Method: Composition-based stats.
 Identities = 20/50 (40%), Positives = 24/50 (48%), Gaps = 2/50 (4%)
 Frame = -2

Query: 748 PFESRSHD--EITIQPGDIVMVDESQTGEPGWLGGELKGKTGWFPANYAE 795
           P   ++ D  EIT  P DI+  +  Q  E  W G    G  G FPANY E
Sbjct: 442 PLRHQAGDDTEITFDPDDII-TNIDQIDEGWWQGFAPDGSYGMFPANYVE 296
>21187
          Length = 1206

 Score = 39.3 bits (90), Expect = 0.015,   Method: Compositional matrix adjust.
 Identities = 19/56 (33%), Positives = 33/56 (58%), Gaps = 5/56 (8%)
 Frame = +2

Query: 910 QAQALYPWRAKKDNHLNFNKSDVITVLEQQ-----DMWWFGEVQGQKGWFPKSYVK 960
           +A A+  + A    +L  N+ D++ +  +      D+W  GEV G+KG+FPK++VK
Sbjct: 128 KATAIGRYPASSPLYLTLNRGDIVEIKSKSAGNRPDLWG-GEVNGRKGYFPKAFVK 292

 Score = 37.7 bits (86), Expect = 0.040,   Method: Compositional matrix adjust.
 Identities = 18/48 (37%), Positives = 27/48 (56%), Gaps = 3/48 (6%)
 Frame = +2

Query: 1159 YTAQNDDELAFSKGQIINVLNKED---PDWWKGEVSGQVGLFPSNYVK 1203
            Y A +   L  ++G I+ + +K     PD W GEV+G+ G FP  +VK
Sbjct: 149  YPASSPLYLTLNRGDIVEIKSKSAGNRPDLWGGEVNGRKGYFPKAFVK 292

 Score = 35.0 bits (79), Expect = 0.25,   Method: Compositional matrix adjust.
 Identities = 19/55 (34%), Positives = 28/55 (50%), Gaps = 7/55 (12%)
 Frame = +2

Query: 757 ITIQPGDIVMVDESQTGE-PGWLGGELKGKTGWFPANYAEKI------PENEVPT 804
           +T+  GDIV +     G  P   GGE+ G+ G+FP  + ++       P  EVPT
Sbjct: 173 LTLNRGDIVEIKSKSAGNRPDLWGGEVNGRKGYFPKAFVKEFHINIHNPMFEVPT 337

 Score = 33.1 bits (74), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 16/52 (30%), Positives = 25/52 (48%), Gaps = 4/52 (7%)
 Frame = +2

Query: 1002 AMYTYESSEQGDLTFQQGDVIVVTKKDG----DWWTGTVGDKSGVFPSNYVR 1049
            A+  Y +S    LT  +GD++ +  K      D W G V  + G FP  +V+
Sbjct: 137  AIGRYPASSPLYLTLNRGDIVEIKSKSAGNRPDLWGGEVNGRKGYFPKAFVK 292
>14539
          Length = 436

 Score = 38.5 bits (88), Expect = 0.021,   Method: Composition-based stats.
 Identities = 25/78 (32%), Positives = 38/78 (48%), Gaps = 6/78 (7%)
 Frame = +3

Query: 1608 GKSNPYCEVTM-GSQCHITK-----TIQDTLNPKWNSNCQFFIRDLEQEVLCITVFERDQ 1661
            G ++P+ E+ + G +C   K      + + LNP WN NC F +   E  +L   V + D 
Sbjct: 72   GIASPFLEIEIAGIECDNQKFKTETRVDNGLNPVWNKNCVFDVLCPELALLRFAVMDEDT 251

Query: 1662 FSPDDFLGRTEIRVADIK 1679
            F   +FLG+    V  IK
Sbjct: 252  FGDPNFLGQGCFPVPCIK 305
>38272
          Length = 749

 Score = 38.5 bits (88), Expect = 0.021,   Method: Composition-based stats.
 Identities = 32/144 (22%), Positives = 65/144 (45%), Gaps = 2/144 (1%)
 Frame = +2

Query: 1364 LSSFILKPMQRVTRYPLIIKNILENTPEN--HPDHSHLKHALEKAEELCSQVNEGVREKE 1421
            LS+ I+ P+QR+T+Y L+I  IL  T     H + + L  A E+ +++  +VN+ +    
Sbjct: 113  LSALIITPVQRITKYVLLINEILRETKRAGLHNEVATLMEAGEQMKDVVKKVNDMMMVLR 292

Query: 1422 NSDRLEWIQAHVQCEGLSEQLVFNSVTNCLGPRKFLHSGKLYKAKSNKELYGFLFNDFLL 1481
                L+     +  +G    L+   +  C           +   +  +EL  FLF   ++
Sbjct: 293  G---LQDFDGEITAQG---NLLLQGILTC----------AIDAGQKQRELQVFLFQQIII 424

Query: 1482 LTQITKPLGSSGTDKVFSPKSNLQ 1505
               I K + +  +  +F  ++++Q
Sbjct: 425  FADIQK-VKTQXSSPIFKYRTHIQ 493
>29243
          Length = 1147

 Score = 38.1 bits (87), Expect = 0.027,   Method: Compositional matrix adjust.
 Identities = 22/58 (37%), Positives = 30/58 (51%), Gaps = 2/58 (3%)
 Frame = +2

Query: 1071 IAQVIASYAATGPEQLTLAPGQLILIRKKN--PGGWWEGELQARGKKRQIGWFPANYV 1126
             A  +  YAAT   QL++     I I  KN    GWW+GE     + ++IG+FP  YV
Sbjct: 635  FAVAVYDYAATSTSQLSMKLNDRIAILSKNGQDKGWWKGE---NLRTQKIGYFPLAYV 799

 Score = 37.4 bits (85), Expect = 0.053,   Method: Compositional matrix adjust.
 Identities = 23/73 (31%), Positives = 34/73 (46%), Gaps = 7/73 (9%)
 Frame = +2

Query: 1137 TPTELPKTAVQPAVCQV---IGMYDYTAQNDDELAFSKGQIINVL--NKEDPDWWKGEV- 1190
            T    P   V    C +   + +YDY A +  +L+      I +L  N +D  WWKGE  
Sbjct: 581  TTLRFPYKDVATXACILGFAVAVYDYAATSTSQLSMKLNDRIAILSKNGQDKGWWKGENL 760

Query: 1191 -SGQVGLFPSNYV 1202
             + ++G FP  YV
Sbjct: 761  RTQKIGYFPLAYV 799

 Score = 32.3 bits (72), Expect = 1.9,   Method: Composition-based stats.
 Identities = 15/36 (41%), Positives = 21/36 (58%), Gaps = 1/36 (2%)
 Frame = +3

Query: 925 LNFNKSDVITVLEQQDM-WWFGEVQGQKGWFPKSYV 959
           L F+K  V+ V+   D  W  G   G++G+FP SYV
Sbjct: 54  LCFDKDHVVDVISDADTEWCRGRFNGEEGYFPSSYV 161
>19562
          Length = 457

 Score = 37.7 bits (86), Expect = 0.041,   Method: Composition-based stats.
 Identities = 20/57 (35%), Positives = 28/57 (49%), Gaps = 1/57 (1%)
 Frame = -1

Query: 1605 RSHGKSNPYCEVTMGSQCHITKT-IQDTLNPKWNSNCQFFIRDLEQEVLCITVFERD 1660
            R  G S+PYC +    +  +T   +  T NP+W S  +FFI D  Q      VF+ D
Sbjct: 412  RQTGASDPYCVLFCNRRRLLTTPYVPATRNPRWESWAEFFIGDFTQSTYSFFVFDWD 242
>31183
          Length = 923

 Score = 37.7 bits (86), Expect = 0.046,   Method: Composition-based stats.
 Identities = 14/31 (45%), Positives = 20/31 (64%)
 Frame = +1

Query: 1174 IINVLNKEDPDWWKGEVSGQVGLFPSNYVKL 1204
            +I  +   D  WW+G   G+ GLFP+NYV+L
Sbjct: 7    VITDIEMIDDGWWRGSCHGKNGLFPANYVEL 99

 Score = 36.2 bits (82), Expect = 0.13,   Method: Composition-based stats.
 Identities = 16/32 (50%), Positives = 20/32 (62%), Gaps = 1/32 (3%)
 Frame = +1

Query: 931 DVITVLEQ-QDMWWFGEVQGQKGWFPKSYVKL 961
           DVIT +E   D WW G   G+ G FP +YV+L
Sbjct: 4   DVITDIEMIDDGWWRGSCHGKNGLFPANYVEL 99

 Score = 35.4 bits (80), Expect = 0.22,   Method: Composition-based stats.
 Identities = 15/33 (45%), Positives = 21/33 (63%), Gaps = 1/33 (3%)
 Frame = +1

Query: 1020 DVIV-VTKKDGDWWTGTVGDKSGVFPSNYVRLK 1051
            DVI  +   D  WW G+   K+G+FP+NYV L+
Sbjct: 4    DVITDIEMIDDGWWRGSCHGKNGLFPANYVELQ 102

 Score = 34.3 bits (77), Expect = 0.42,   Method: Composition-based stats.
 Identities = 16/33 (48%), Positives = 18/33 (54%)
 Frame = +1

Query: 763 DIVMVDESQTGEPGWLGGELKGKTGWFPANYAE 795
           DI M+D+      GW  G   GK G FPANY E
Sbjct: 16  DIEMIDD------GWWRGSCHGKNGLFPANYVE 96
>07198
          Length = 1675

 Score = 37.0 bits (84), Expect = 0.066,   Method: Composition-based stats.
 Identities = 17/55 (30%), Positives = 29/55 (52%)
 Frame = -3

Query: 226 RQLFNSHDKTMSGHLTGPQARTILMQSSLPQAQLASIWNLSDIDQDGKLTAEEFI 280
           R++F++ D    G L   +     M +S PQ +L      SD ++DG ++ EEF+
Sbjct: 473 RKVFDAADANKDGSLNSKEYFAFFMPNSFPQLELERFMRQSDKNKDGTISMEEFM 309
>27252
          Length = 378

 Score = 35.4 bits (80), Expect = 0.20,   Method: Compositional matrix adjust.
 Identities = 27/91 (29%), Positives = 43/91 (47%), Gaps = 2/91 (2%)
 Frame = +2

Query: 1069 PEIAQVIA--SYAATGPEQLTLAPGQLILIRKKNPGGWWEGELQARGKKRQIGWFPANYV 1126
            P +A+VI   + +A    QL L  G+ I +   N  G WEGE+  R      G FP  +V
Sbjct: 116  PALARVILDRTPSAYDRTQLKLKQGETIKVLAINIDGQWEGEINGR-----TGKFPFTHV 280

Query: 1127 KLLSPGTSKITPTELPKTAVQPAVCQVIGMY 1157
            + LS     +T   + +      VC+ +G++
Sbjct: 281  EFLSEDEQPVT*CGM*RVTC--GVCR*LGIH 367
>13641
          Length = 2081

 Score = 35.0 bits (79), Expect = 0.26,   Method: Compositional matrix adjust.
 Identities = 17/58 (29%), Positives = 32/58 (55%), Gaps = 12/58 (20%)
 Frame = +2

Query: 1002 AMYTYES-------SEQGDLTFQQGDVI-VVTKKDGDWW----TGTVGDKSGVFPSNY 1047
            AM+++ S        ++  L+FQQGD++ +V ++D  WW     G    ++G+ PS +
Sbjct: 164  AMFSFNSKLDDNIPCKEAGLSFQQGDILHIVNQEDAIWWQAYKHGDAKKRAGLIPSRH 337
>05050
          Length = 827

 Score = 31.6 bits (70), Expect = 3.0,   Method: Composition-based stats.
 Identities = 12/24 (50%), Positives = 18/24 (75%)
 Frame = +3

Query: 887 TPATATGSSPSPVLGQGEKVEGLQ 910
           +P   +G+SPSP+LGQG K+  L+
Sbjct: 270 SPGCFSGASPSPILGQGPKLSDLR 341
>20374
          Length = 357

 Score = 31.2 bits (69), Expect = 3.4,   Method: Composition-based stats.
 Identities = 19/48 (39%), Positives = 26/48 (54%)
 Frame = -2

Query: 88  KLQGYQLPSTLPPVMKQQPVAISSAPAFGIGGIASMPPLTAVAPVPMG 135
           KLQGY+LP  LP  +K  P     +P  G  G+ +  P++   PV MG
Sbjct: 344 KLQGYELPKVLPASLKAAP-----SPVIGSFGMQA-GPMSMGQPVVMG 219
>18881
          Length = 762

 Score = 31.2 bits (69), Expect = 3.7,   Method: Composition-based stats.
 Identities = 21/48 (43%), Positives = 25/48 (52%), Gaps = 2/48 (4%)
 Frame = -3

Query: 1081 TGPEQLTLAPGQLILIRKKN--PGGWWEGELQARGKKRQIGWFPANYV 1126
            T   Q+TL     I I  KN    GWW+GE   R KK  +G+FP  YV
Sbjct: 451  TSTTQVTLKLNDRISILSKNGQDKGWWKGE-NLRTKK--VGYFPLAYV 317
>36643
          Length = 601

 Score = 31.2 bits (69), Expect = 3.9,   Method: Compositional matrix adjust.
 Identities = 24/81 (29%), Positives = 38/81 (46%)
 Frame = +1

Query: 1071 IAQVIASYAATGPEQLTLAPGQLILIRKKNPGGWWEGELQARGKKRQIGWFPANYVKLLS 1130
            +AQ + S+   G E+L+ + GQ +++  K       G L A    R+ G  P NY+K+L 
Sbjct: 193  VAQTLFSFTGQGEEELSFSAGQQLILAPKEVQPQVRGWLLASVGGRK-GLVPYNYIKILG 369

Query: 1131 PGTSKITPTELPKTAVQPAVC 1151
                +        TA QPA+ 
Sbjct: 370  KRRGRQQNASASPTAPQPAIA 432
>07591
          Length = 796

 Score = 31.2 bits (69), Expect = 3.9,   Method: Compositional matrix adjust.
 Identities = 21/82 (25%), Positives = 36/82 (43%), Gaps = 9/82 (10%)
 Frame = +2

Query: 1608 GKSNPYCEVTMGSQ------CHITKTIQDTLNPKWNS---NCQFFIRDLEQEVLCITVFE 1658
            GKS+PY EV   +        H T+ +++ LNP W     + Q       Q+ +   V++
Sbjct: 509  GKSDPYLEVLRATSDGSWQMVHRTEVVKNNLNPSWRPFELSMQTLCGGNHQQNIKFDVYD 688

Query: 1659 RDQFSPDDFLGRTEIRVADIKK 1680
             D     D++G     + D+ K
Sbjct: 689  WDSDGSHDYIGGFTTTLQDMLK 754
>05206
          Length = 1075

 Score = 30.8 bits (68), Expect = 4.8,   Method: Composition-based stats.
 Identities = 19/63 (30%), Positives = 34/63 (53%), Gaps = 3/63 (4%)
 Frame = +1

Query: 901 GQGEKVEGLQAQALYPWRAKKDNHLNFNKSDVITVLE--QQDMWW-FGEVQGQKGWFPKS 957
           G+GE +     +ALYP+ A  +  +   +++ + +LE  Q D W    +  G +G+ P S
Sbjct: 67  GEGEFIVIGTCRALYPFEAMNEGSVPMGENEEMQILEEDQGDGWTRVRKADGSEGFVPSS 246

Query: 958 YVK 960
           YV+
Sbjct: 247 YVQ 255
>14594
          Length = 1014

 Score = 30.8 bits (68), Expect = 5.0,   Method: Composition-based stats.
 Identities = 15/60 (25%), Positives = 31/60 (51%), Gaps = 2/60 (3%)
 Frame = +3

Query: 226 RQLFNSHDKTMSGHLTGPQARTIL--MQSSLPQAQLASIWNLSDIDQDGKLTAEEFILAM 283
           R+ F   DK  +G+++  + R ++  +   L   ++  +   +D+D DG +  EEF+  M
Sbjct: 669 REAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIKEADLDGDGMVNYEEFVTMM 848
>11228
          Length = 2155

 Score = 30.4 bits (67), Expect = 6.1,   Method: Compositional matrix adjust.
 Identities = 18/58 (31%), Positives = 31/58 (53%), Gaps = 4/58 (6%)
 Frame = -2

Query: 1001 IAMYTYESSEQGD-LTFQQGDVIVVTKKDGDWWTGTVGDK---SGVFPSNYVRLKDSE 1054
            +AM +Y  +   D L+F +GDV VV  +  D W     ++   SG+ P+ +V+  D +
Sbjct: 1662 VAMLSYRKATDSDELSFCKGDVFVVQNEMEDGWLWVTCERTKESGLVPAPFVKDLDGD 1489
>05237
          Length = 472

 Score = 30.0 bits (66), Expect = 7.4,   Method: Composition-based stats.
 Identities = 16/60 (26%), Positives = 31/60 (51%), Gaps = 2/60 (3%)
 Frame = +3

Query: 226 RQLFNSHDKTMSGHLTGPQARTIL--MQSSLPQAQLASIWNLSDIDQDGKLTAEEFILAM 283
           R+ F   DK  +G ++  + R ++  +   L   ++  +   +DID DG++  EEF+  M
Sbjct: 36  REAFRVFDKDGNGFISASELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVKMM 215
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|55741460|ref|NP_065594.2| Parkinson disease protein 7
[Mus musculus]
         (189 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

04345                                                                 100   6e-43
00206                                                                  35   0.019
03247                                                                  30   0.62 
03141                                                                  30   0.63 
35714                                                                  28   1.6  
>04345
          Length = 2153

 Score =  100 bits (249), Expect(2) = 6e-43,   Method: Compositional matrix adjust.
 Identities = 54/111 (48%), Positives = 74/111 (66%)
 Frame = -3

Query: 78   GAQNLSESPMVKEILKEQESRKGLIAAICAGPTALLAHEVGFGCKVTTHPLAKDKMMNGS 137
            GA+ L ES  V + L+EQE+R G IAA+CA PTAL++H +G G  VT++P    +M +G 
Sbjct: 1821 GAKILKESKAVGDALREQENRGGFIAAVCAAPTALMSHGIGKGKTVTSYPSFGQEMKDGG 1642

Query: 138  HYSYSESRVEKDGLILTSRGPGTSFEFALAIVEALVGKDMANQVKAPLVLK 188
             Y YSE  V +   ++TSRGPGT FEFAL IVE LV K+ A  +   +++K
Sbjct: 1641 -YKYSEDCVVQADKLITSRGPGTCFEFALKIVENLVSKEKAKTLVEQMLVK 1492

 Score = 90.5 bits (223), Expect(2) = 6e-43,   Method: Compositional matrix adjust.
 Identities = 47/76 (61%), Positives = 61/76 (80%)
 Frame = -1

Query: 6    ALVILAKGAEEMETVIPVDVMRRAGIKVTVAGLAGKDPVQCSRDVMICPDTSLEDAKTQG 65
            ALV+LA+GAEEMETVI VDV+RRAGI+V + G++GK PV+CSR+V I PD S E+A  + 
Sbjct: 2033 ALVLLAEGAEEMETVITVDVLRRAGIEVILXGVSGKGPVKCSRNVSIVPDMSXEEAVGKH 1854

Query: 66   PYDVVVLPGGNLGAQN 81
             YDV+VLPGG  G ++
Sbjct: 1853 -YDVLVLPGGVQGPKS 1809
>00206
          Length = 1950

 Score = 35.0 bits (79), Expect = 0.019,   Method: Compositional matrix adjust.
 Identities = 24/68 (35%), Positives = 34/68 (50%), Gaps = 10/68 (14%)
 Frame = +3

Query: 67  YDVVVLPGGNLGAQNLSE----------SPMVKEILKEQESRKGLIAAICAGPTALLAHE 116
           +D V+ PGG   A+NLS           +P V+ +LKE    +  I   C  P  +LA +
Sbjct: 132 FDAVIFPGGFGAAKNLSSFAVDGTAMTVNPDVERVLKEFHGAQKPIGLCCIAP--VLAAK 305

Query: 117 VGFGCKVT 124
           V  GC+VT
Sbjct: 306 VIPGCEVT 329
>03247
          Length = 1092

 Score = 30.0 bits (66), Expect = 0.62,   Method: Compositional matrix adjust.
 Identities = 24/74 (32%), Positives = 33/74 (44%), Gaps = 3/74 (4%)
 Frame = -1

Query: 38  LAGKDPVQCSRDVMICPDTSLEDAKTQGPYDVVVLPGGNLGAQNLSESPMVKEILKEQES 97
              +DP  C +   +  D  L+  K QGP+D ++  G + GA       MV  IL EQE 
Sbjct: 711 FHAQDPSDCCKGYDLSRDVVLQAIKQQGPFDGIL--GFSQGAS------MVSLILGEQEQ 556

Query: 98  ---RKGLIAAICAG 108
              R    A + AG
Sbjct: 555 QPERWFQFAILVAG 514
>03141
          Length = 845

 Score = 30.0 bits (66), Expect = 0.63,   Method: Compositional matrix adjust.
 Identities = 24/74 (32%), Positives = 33/74 (44%), Gaps = 3/74 (4%)
 Frame = +3

Query: 38  LAGKDPVQCSRDVMICPDTSLEDAKTQGPYDVVVLPGGNLGAQNLSESPMVKEILKEQES 97
              +DP  C +   +  D  L+  K QGP+D ++  G + GA       MV  IL EQE 
Sbjct: 306 FHAQDPSDCCKGYDLSRDVVLQAIKQQGPFDGIL--GFSQGAS------MVSLILGEQEQ 461

Query: 98  ---RKGLIAAICAG 108
              R    A + AG
Sbjct: 462 QPERWFQFAILVAG 503
>35714
          Length = 788

 Score = 28.5 bits (62), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 24/87 (27%), Positives = 39/87 (44%), Gaps = 2/87 (2%)
 Frame = +3

Query: 64  QGPYDVVVLPGGNLGAQNLSESPMVKEILKEQESRKGLIAAICAGPTALLAHEVGFGCKV 123
           QG  D+++  G     + + + PM     K   S K  + +   GPT  + +   F    
Sbjct: 84  QGEKDLIIRDG-----KLVKKRPMTDTDDKTSRSDKH*LPSDTKGPTVEVVNSDLFSSDF 248

Query: 124 TTHPLAKDK--MMNGSHYSYSESRVEK 148
             +PL K K   +NG H+S+  SR E+
Sbjct: 249 --NPLCKLKPCNLNGQHHSFDNSRGEE 323
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|13470090|ref|NP_076341.1| RAB3C, member RAS oncogene
family [Mus musculus]
         (227 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

33380                                                                 164   7e-43
08428                                                                 122   1e-28
33374                                                                 100   6e-26
34468                                                                 112   1e-25
05468                                                                 110   5e-25
26083                                                                 105   2e-23
07465                                                                 103   7e-23
17511                                                                  95   2e-20
07580                                                                  94   5e-20
13901                                                                  92   2e-19
13750                                                                  90   7e-19
33794                                                                  89   1e-18
14456                                                                  88   3e-18
11257                                                                  83   7e-17
01398                                                                  82   2e-16
32723                                                                  81   3e-16
01972                                                                  71   3e-16
26536                                                                  80   5e-16
30760                                                                  77   4e-15
12339                                                                  75   2e-14
34597                                                                  70   4e-14
19006                                                                  71   3e-13
11728                                                                  69   1e-12
35581                                                                  65   3e-11
34359                                                                  64   4e-11
13745                                                                  63   1e-10
19046                                                                  62   2e-10
24619                                                                  60   5e-10
01095                                                                  59   1e-09
27191                                                                  57   4e-09
00858                                                                  57   7e-09
19656                                                                  56   1e-08
31291                                                                  54   6e-08
09204                                                                  52   3e-07
00552                                                                  50   9e-07
14775                                                                  49   1e-06
29380                                                                  49   2e-06
09827                                                                  48   3e-06
08153                                                                  48   3e-06
14119                                                                  42   3e-04
10862                                                                  38   0.003
33605                                                                  37   0.005
25796                                                                  32   0.23 
10708                                                                  31   0.39 
06994                                                                  29   1.9  
18184                                                                  28   2.2  
07531                                                                  28   2.8  
31932                                                                  28   4.4  
31928                                                                  27   4.6  
>33380
          Length = 282

 Score =  164 bits (415), Expect(2) = 7e-43,   Method: Compositional matrix adjust.
 Identities = 73/82 (89%), Positives = 79/82 (96%)
 Frame = +3

Query: 71  TVFKNEKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEESFNAVQDWSTQIKT 130
           TVF+ +KR+KLQIWDTAGQERYRTITTAYYRGAMGFILMYD+TNEESFNAVQDW TQIKT
Sbjct: 36  TVFRQDKRVKLQIWDTAGQERYRTITTAYYRGAMGFILMYDVTNEESFNAVQDWCTQIKT 215

Query: 131 YSWDNAQVILAGNKCDMEDERV 152
           YSWDNAQV+L GNKCD+EDERV
Sbjct: 216 YSWDNAQVVLVGNKCDLEDERV 281

 Score = 26.9 bits (58), Expect(2) = 7e-43,   Method: Compositional matrix adjust.
 Identities = 11/14 (78%), Positives = 13/14 (92%)
 Frame = +2

Query: 59 FVSTVGIDFKVKTV 72
          FVSTVGIDFKV ++
Sbjct: 2  FVSTVGIDFKVNSL 43
>08428
          Length = 1109

 Score =  122 bits (305), Expect = 1e-28,   Method: Compositional matrix adjust.
 Identities = 55/156 (35%), Positives = 93/156 (59%)
 Frame = -3

Query: 32   KLLIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVFKNEKRIKLQIWDTAGQER 91
            K+ ++G+S VGK+S + R+   S+  +  ST+G  F  K++  +    + QIWDTAGQE+
Sbjct: 1065 KVCLLGDSGVGKSSIVLRFVTGSYRPSQESTIGASFMSKSLVVDGAGYRFQIWDTAGQEK 886

Query: 92   YRTITTAYYRGAMGFILMYDITNEESFNAVQDWSTQIKTYSWDNAQVILAGNKCDMEDER 151
            +R +   YYRGA   +++YD+T   +F +V+ W  +++++   N  + +AGNKCD+E+ R
Sbjct: 885  FRALAPMYYRGAAAAVIVYDVTRPRTFKSVKSWIQELRSFGPPNIVLAIAGNKCDLEELR 706

Query: 152  VVSTERGQRLGEQLGFEFFETSAKDNINVKQTFERL 187
             V  +  Q     +   F ETSA   +NV++ F  L
Sbjct: 705  EVVEKDAQEYASSISAIFGETSAMTAVNVEEMFTEL 598
>33374
          Length = 489

 Score =  100 bits (248), Expect(2) = 6e-26,   Method: Compositional matrix adjust.
 Identities = 47/114 (41%), Positives = 71/114 (62%)
 Frame = +1

Query: 67  FKVKTVFKNEKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEESFNAVQDWST 126
           F  +TV  ++  +K +IWDTAGQERY ++   YYRGA   I++YDITN+++F   + W  
Sbjct: 139 FLTQTVCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNQDTFGRAKTWVK 318

Query: 127 QIKTYSWDNAQVILAGNKCDMEDERVVSTERGQRLGEQLGFEFFETSAKDNINV 180
           +++  +  N  + LAGNK D+ ++R+V  E  Q   E+    F ETSAK  +NV
Sbjct: 319 ELQRQASPNIVIALAGNKADLANKRMVEFEEAQAYAEENSLLFMETSAKTAMNV 480

 Score = 34.3 bits (77), Expect(2) = 6e-26,   Method: Compositional matrix adjust.
 Identities = 15/37 (40%), Positives = 23/37 (62%)
 Frame = +2

Query: 31 FKLLIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDF 67
          FKL+++G S+VGK+S + R+    F     ST+G  F
Sbjct: 32 FKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAF 142
>34468
          Length = 1502

 Score =  112 bits (280), Expect = 1e-25,   Method: Compositional matrix adjust.
 Identities = 54/150 (36%), Positives = 88/150 (58%), Gaps = 2/150 (1%)
 Frame = +1

Query: 30  MFKLLIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVFKNEKRIKLQIWDTAGQ 89
           +FK+++IG+S+VGKT   +R+    F     +T+G+DF+ K++  + + +KLQ+WDTAGQ
Sbjct: 493 IFKIIVIGDSNVGKTCLTYRFCLGKFPDKTEATIGVDFREKSIQVDSEHLKLQLWDTAGQ 672

Query: 90  ERYR-TITTAYYRGAMGFILMYDITNEESFNAVQDWSTQIKTYSWDN-AQVILAGNKCDM 147
           ER+R ++   YYR     + +YD+T   SF  +  W  +   ++       IL GNKCD+
Sbjct: 673 ERFRKSMVQHYYRNVHAVVFVYDMTKMSSFENMPAWIEECDRHNLTKYIPRILVGNKCDV 852

Query: 148 EDERVVSTERGQRLGEQLGFEFFETSAKDN 177
            +   V+T   Q+  +      FETSAKD+
Sbjct: 853 VERIAVNTNLAQKFADAHNMPLFETSAKDD 942
>05468
          Length = 1558

 Score =  110 bits (274), Expect = 5e-25,   Method: Compositional matrix adjust.
 Identities = 62/174 (35%), Positives = 103/174 (59%), Gaps = 7/174 (4%)
 Frame = -3

Query: 28   DYMFKLLIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTV-FKNEKRIKLQIWDT 86
            ++++K+L+IG    GKTS + RY    F+  + +T+G+DF +K + +  +  I+LQ+WD 
Sbjct: 1547 EHLYKILVIGELGTGKTSIIKRYVHQFFSQHYRATIGVDFALKVLNWDADTLIRLQLWDI 1368

Query: 87   AGQERYRTITTAYYRGAMGFILMYDITNEESFNAVQDWSTQI--KTYSWDNAQV--ILAG 142
            AGQER+  +T  YY+ A+G  +++D+T   +F+AV  W   +  K    D + V  +L  
Sbjct: 1367 AGQERFGNMTRVYYKEAVGAFVVFDVTRASTFDAVTKWKNDLDSKVQLADGSPVPCVLLA 1188

Query: 143  NKCDMEDERVV-STERGQRLGEQLGF-EFFETSAKDNINVKQTFERLVDIICDK 194
            NKCD   E +V +T +      + GF  ++ETSAK+NIN+ +    LV  I +K
Sbjct: 1187 NKCDQAKEGLVNNTSQMDEFCSEKGFIGWYETSAKENINIDEAARFLVTRILEK 1026
>26083
          Length = 432

 Score =  105 bits (261), Expect = 2e-23,   Method: Compositional matrix adjust.
 Identities = 48/114 (42%), Positives = 76/114 (66%)
 Frame = +1

Query: 31  FKLLIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVFKNEKRIKLQIWDTAGQE 90
           FKL+ +G  SVGKTS + R+  DSF + + +T+GIDF  KT++  ++ I+LQ+WDTAGQE
Sbjct: 79  FKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTIRLQLWDTAGQE 258

Query: 91  RYRTITTAYYRGAMGFILMYDITNEESFNAVQDWSTQIKTYSWDNAQVILAGNK 144
           R+R++  +Y R +   +++YDITN  SF+    W   ++T    +  ++L GNK
Sbjct: 259 RFRSLIPSYIRDSSVAVVVYDITNANSFHQTSKWIDDVRTERGSDVIIMLVGNK 420
>07465
          Length = 1103

 Score =  103 bits (256), Expect = 7e-23,   Method: Compositional matrix adjust.
 Identities = 51/157 (32%), Positives = 88/157 (56%)
 Frame = +3

Query: 44  TSFLFRYADDSFTSAFVSTVGIDFKVKTVFKNEKRIKLQIWDTAGQERYRTITTAYYRGA 103
           +S + RY    FT  +  T+G+DF  + +    + ++L +WDTAGQE +  IT AYYRGA
Sbjct: 240 SSMIQRYCKGIFTKDYKKTIGVDFLERQIEVGGEDVRLMLWDTAGQEEFDAITKAYYRGA 419

Query: 104 MGFILMYDITNEESFNAVQDWSTQIKTYSWDNAQVILAGNKCDMEDERVVSTERGQRLGE 163
              +L +   + +SF A++ W  +++    +   VI+  NK D+ D+ VV  E  + L +
Sbjct: 420 QACVLAFSTVDRDSFEALETWKRKVEDEVGEIGMVIVQ-NKIDLIDDAVVRPEEAENLAK 596

Query: 164 QLGFEFFETSAKDNINVKQTFERLVDIICDKMSESLE 200
           +L   F+ TS K+N+NV + F  L D    +++  ++
Sbjct: 597 KLRLRFYRTSVKENMNVDEVFRYLADKYLHQLNTGMD 707
>17511
          Length = 483

 Score = 95.1 bits (235), Expect = 2e-20,   Method: Compositional matrix adjust.
 Identities = 43/122 (35%), Positives = 77/122 (63%), Gaps = 4/122 (3%)
 Frame = -3

Query: 30  MFKLLIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVFKNEKRIKLQIWDTAGQ 89
           + K++I+G+S VGKTS + +Y +  F++ + +T+G DF  K V  +++ + +QIWDTAGQ
Sbjct: 367 LLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQIWDTAGQ 188

Query: 90  ERYRTITTAYYRGAMGFILMYDITNEESFNAVQDWS----TQIKTYSWDNAQVILAGNKC 145
           ER++++  A+YRGA   +L++D+T   +F ++  W      Q      +N   ++ GNK 
Sbjct: 187 ERFQSLGVAFYRGADCCVLVFDVTMPNTFRSLDSWRDEFLIQASPRDPENFPFVVIGNKI 8

Query: 146 DM 147
           D+
Sbjct: 7   DL 2
>07580
          Length = 921

 Score = 93.6 bits (231), Expect = 5e-20,   Method: Compositional matrix adjust.
 Identities = 52/129 (40%), Positives = 73/129 (56%), Gaps = 1/129 (0%)
 Frame = +3

Query: 70  KTVFKNEKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEESFNAVQDWSTQI- 128
           K V  + ++  L+I DTAG E++  +   Y +   GF+L Y IT + +FN +Q+   QI 
Sbjct: 177 KQVEVDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFLLAYSITAQSTFNDLQELREQIL 356

Query: 129 KTYSWDNAQVILAGNKCDMEDERVVSTERGQRLGEQLGFEFFETSAKDNINVKQTFERLV 188
           +    D+  ++L GNKCD+EDERVV  ++GQ L       F ETSAK  INV + F  LV
Sbjct: 357 RVKDTDDVPMLLVGNKCDLEDERVVGKDQGQGLARSFSCAFLETSAKARINVNEIFMDLV 536

Query: 189 DIICDKMSE 197
             I  K  E
Sbjct: 537 RQINKKSPE 563
>13901
          Length = 962

 Score = 92.0 bits (227), Expect = 2e-19,   Method: Compositional matrix adjust.
 Identities = 42/96 (43%), Positives = 67/96 (69%), Gaps = 1/96 (1%)
 Frame = -3

Query: 30  MFKLLIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVFKNEK-RIKLQIWDTAG 88
           +FK++IIG+ +VGKTSF+ RY +DSF   +  T+G+DF +K +  ++K  IKLQ+WD AG
Sbjct: 288 LFKVIIIGDPTVGKTSFVQRYVNDSFRRDYKMTIGVDFALKVIRWSDKCNIKLQLWDIAG 109

Query: 89  QERYRTITTAYYRGAMGFILMYDITNEESFNAVQDW 124
           QER+ ++T  YY+ A   I+M+D+T + ++     W
Sbjct: 108 QERFTSMTRVYYKDAHACIVMFDLTQKNTYQNAIRW 1
>13750
          Length = 503

 Score = 90.1 bits (222), Expect = 7e-19,   Method: Compositional matrix adjust.
 Identities = 57/155 (36%), Positives = 83/155 (53%), Gaps = 6/155 (3%)
 Frame = -2

Query: 43  KTSFLFRYADDSFTSAFVSTVGIDFKVKTVFKNEKR-----IKLQIWDTAGQERYRTITT 97
           KT  L RY    F    + T+ +   + + F NE R     ++  +WDT G E YR++  
Sbjct: 502 KTCLLRRYQKGFFMDRTMPTIAV---LCSEF-NESRTDPLNVRYTLWDTGGAETYRSLWV 335

Query: 98  AYYRGAMGFILMYDITNEESF-NAVQDWSTQIKTYSWDNAQVILAGNKCDMEDERVVSTE 156
           +++RGA   +L+YD+T E SF  A   W   +   +   AQVI  G+K D+E+ RV+STE
Sbjct: 334 SHFRGAQVALLVYDVTCEWSFLTATTVWRKALMK-NIPEAQVIFVGSKTDLEENRVISTE 158

Query: 157 RGQRLGEQLGFEFFETSAKDNINVKQTFERLVDII 191
           RGQ    Q G+ FFETS+    NV   F  +  I+
Sbjct: 157 RGQAFATQCGYTFFETSSVTGKNVDAVFWEIAFIL 53
>33794
          Length = 779

 Score = 89.4 bits (220), Expect = 1e-18,   Method: Compositional matrix adjust.
 Identities = 46/132 (34%), Positives = 76/132 (57%)
 Frame = -1

Query: 56  TSAFVSTVGIDFKVKTVFKNEKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNE 115
           TS  + TV   +K  T+    KR+KLQIWDT+GQ R+ TI  +Y RGA G IL+YDITN+
Sbjct: 713 TSHILQTVA--YKTTTILLEGKRVKLQIWDTSGQGRFCTIIRSYSRGAQGIILVYDITNK 540

Query: 116 ESFNAVQDWSTQIKTYSWDNAQVILAGNKCDMEDERVVSTERGQRLGEQLGFEFFETSAK 175
            SF+ +  W  +++ ++      +L GN+  +  +R V+ ++ +    +     FE S  
Sbjct: 539 WSFDGIDRWLKEVEEHA-PGIPKVLVGNRLHLAYKRQVAAKQAETYASRNNMSCFEISPL 363

Query: 176 DNINVKQTFERL 187
            + N++++F  L
Sbjct: 362 CDFNIRESFCEL 327
>14456
          Length = 1867

 Score = 87.8 bits (216), Expect = 3e-18,   Method: Compositional matrix adjust.
 Identities = 49/153 (32%), Positives = 83/153 (54%), Gaps = 4/153 (2%)
 Frame = -1

Query: 36   IGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVFKNEKRIKLQIWDTAGQERYRTI 95
            +    VGK+S + R+  + F +    T+G++F  K V  +++   +QIWDTAGQER++++
Sbjct: 1123 LKQGGVGKSSLMNRFVSNKFDAQSFHTIGVEFLNKDVVVDDETYTMQIWDTAGQERFKSL 944

Query: 96   TTAYYRGAMGFILMYDITNEESFNAVQDWSTQIKTYSWDNAQV----ILAGNKCDMEDER 151
             T +YRGA   +L + + + +SF  +  W  +   Y+     V    ++ GNK D+E  +
Sbjct: 943  RTPFYRGADCCLLTFSVDSMQSFRNLSMWRKEFLYYADIQDGVTFPFVVLGNKIDVEGRQ 764

Query: 152  VVSTERGQRLGEQLGFEFFETSAKDNINVKQTF 184
            V + E            +FETSAKD  NV++ F
Sbjct: 763  VTNEEARSWCTANSNAPYFETSAKDATNVEKAF 665
>11257
          Length = 1102

 Score = 83.2 bits (204), Expect = 7e-17,   Method: Compositional matrix adjust.
 Identities = 52/142 (36%), Positives = 81/142 (57%), Gaps = 5/142 (3%)
 Frame = -2

Query: 70   KTVFKNEKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEESFNAVQDWSTQIK 129
            K V  + +   +QIWDTAGQERY+++ T +YRG    +L + + N +S  ++ DW  +  
Sbjct: 1053 KDVVVDGETFTMQIWDTAGQERYKSLRTPFYRGTDCCLLTFSVDNLKSLQSLSDWYDEFV 874

Query: 130  TYS--WDNAQ--VILAGNKCDMEDERVVSTERGQRLGEQLG-FEFFETSAKDNINVKQTF 184
             Y+   D+A    ++ GNK D+E ER VS+E         G   +FETSAKD++NV+Q F
Sbjct: 873  NYADIQDSASFPFVIIGNKADIE-EREVSSEDAYNWCRTHGNLPYFETSAKDSLNVQQAF 697

Query: 185  ERLVDIICDKMSESLETDPAIT 206
              +V  +  +M E ++  P  T
Sbjct: 696  LAVVRRL-REMDEQMDERPTRT 634
>01398
          Length = 1421

 Score = 81.6 bits (200), Expect = 2e-16,   Method: Compositional matrix adjust.
 Identities = 38/100 (38%), Positives = 61/100 (61%), Gaps = 1/100 (1%)
 Frame = -2

Query: 89   QERYRTITTAYYRGAMGFILMYDITNEESFNAVQDWSTQIKTYSWDNAQVILA-GNKCDM 147
            QER+R+IT +YYR ++G I++YDIT   +F  ++ W  + + +   +  + L  G+K D 
Sbjct: 1420 QERFRSITRSYYRNSVGVIIVYDITKRSTFENLKQWYEEARNHIEPHKAIFLVLGHKSDR 1241

Query: 148  EDERVVSTERGQRLGEQLGFEFFETSAKDNINVKQTFERL 187
            ED R V+   G+R  E  G +FFETSAK   N++  F ++
Sbjct: 1240 EDARQVTAREGRRFAEMHGLKFFETSAKSGHNIEDVFAQI 1121
>32723
          Length = 384

 Score = 81.3 bits (199), Expect = 3e-16,   Method: Compositional matrix adjust.
 Identities = 37/96 (38%), Positives = 58/96 (60%)
 Frame = +2

Query: 89  QERYRTITTAYYRGAMGFILMYDITNEESFNAVQDWSTQIKTYSWDNAQVILAGNKCDME 148
           QER+R+IT +YYR A   IL+YD+ +++S+ ++  W  +I+ Y+       L GNK D  
Sbjct: 2   QERFRSITQSYYRSANALILVYDVCSQQSYESLPQWIHEIELYAGTKVLAFLVGNKIDQT 181

Query: 149 DERVVSTERGQRLGEQLGFEFFETSAKDNINVKQTF 184
           D+R + T  G+   E+    F ETSAK+  NV++ F
Sbjct: 182 DKREIPTHIGKEFAERYEMRFLETSAKEADNVEKLF 289
>01972
          Length = 2359

 Score = 70.9 bits (172), Expect(2) = 3e-16,   Method: Compositional matrix adjust.
 Identities = 38/148 (25%), Positives = 77/148 (52%), Gaps = 1/148 (0%)
 Frame = +3

Query: 59  FVSTVGIDFKVKTVFKNEKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEESF 118
           +V+T+G++        +  ++K  +WDTAGQE++  +   YY      ++M+D+T+  ++
Sbjct: 387 YVATLGVEVHPLLFHTSRGKLKFNVWDTAGQEKFGGLRDGYYIQGQCAVIMFDVTSRVTY 566

Query: 119 NAVQDWSTQIKTYSWDNAQVILAGNKCDMEDERVVSTERGQRLGEQLGFEFFETSAKDNI 178
             V +W   +     +N  ++L GNK D++D +V    +      +   ++++ SAK N 
Sbjct: 567 KNVPNWHRDLVRVC-ENIPIVLCGNKVDIKDRKV--KAKAIVFHRKKNLQYYDISAKSNY 737

Query: 179 NVKQTFERLV-DIICDKMSESLETDPAI 205
           N ++ F  L   ++ D   E +E  PA+
Sbjct: 738 NFEKPFLWLARKLVGDPNLEFVEM-PAL 818

 Score = 30.8 bits (68), Expect(2) = 3e-16,   Method: Compositional matrix adjust.
 Identities = 11/25 (44%), Positives = 18/25 (72%)
 Frame = +1

Query: 31  FKLLIIGNSSVGKTSFLFRYADDSF 55
           FKL+++G+  VGKT+F+ R+    F
Sbjct: 304 FKLVLVGDGGVGKTTFVKRHVTGEF 378
>26536
          Length = 829

 Score = 80.5 bits (197), Expect = 5e-16,   Method: Compositional matrix adjust.
 Identities = 44/119 (36%), Positives = 68/119 (57%), Gaps = 3/119 (2%)
 Frame = +2

Query: 76  EKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEESFN---AVQDWSTQIKTYS 132
           E+R+     DTAGQE Y ++   Y R   GFI++Y +T+  SF    AV  W T+ +  +
Sbjct: 119 ERRVSWTFLDTAGQEEYSSMREHYTRSGDGFIVVYSVTDVTSFQEAEAVFRWLTRFQDET 298

Query: 133 WDNAQVILAGNKCDMEDERVVSTERGQRLGEQLGFEFFETSAKDNINVKQTFERLVDII 191
             +   +L GNK D+  +R V+ E G+++ ++LG  +FETSAK   NV Q +  L+  I
Sbjct: 299 --SIHAVLCGNKTDLTSDRKVTPEEGRKMADRLGMLYFETSAKTGDNVSQVYHGLLRSI 469

 Score = 30.0 bits (66), Expect = 0.90,   Method: Compositional matrix adjust.
 Identities = 10/33 (30%), Positives = 21/33 (63%)
 Frame = +2

Query: 31  FKLLIIGNSSVGKTSFLFRYADDSFTSAFVSTV 63
           +K++++G+  VGK+S   R+  D+F   +  T+
Sbjct: 488 YKIVMLGSGGVGKSSLTIRFTQDTFLDVYDPTI 586
>30760
          Length = 596

 Score = 77.4 bits (189), Expect = 4e-15,   Method: Compositional matrix adjust.
 Identities = 47/158 (29%), Positives = 84/158 (53%), Gaps = 5/158 (3%)
 Frame = -1

Query: 32  KLLIIGNSSVGKTSFLFRYADDS--FTSAFVSTVGIDFKVKTVFKNEKR--IKLQIWDTA 87
           K ++ G+S VGK+S    +  DS  F   +  T G++  VK V   + R  ++L ++D+A
Sbjct: 524 KCIVTGDSGVGKSSICQVFHSDSAHFPKNYSMTTGVEVLVKLVNIPDSRDQVELYLFDSA 345

Query: 88  GQERYRTITTAYYRGAMGFILMYDITNEESFNAVQDWSTQIKTYSWDNA-QVILAGNKCD 146
           G+E +    T ++      +++YD+T+E SF+    W  +++    +     +L  NK D
Sbjct: 344 GKEIFSENVTKFWDQPSVVMVVYDVTDETSFSGCVRWLERVRAAKPNTVIPGVLVANKTD 165

Query: 147 MEDERVVSTERGQRLGEQLGFEFFETSAKDNINVKQTF 184
           +++ R VS + G+ L +  G E+FE SAK+  N    F
Sbjct: 164 LDERRRVSRKEGKDLAQSHGLEYFECSAKEMQNTDTPF 51
>12339
          Length = 578

 Score = 75.5 bits (184), Expect = 2e-14,   Method: Compositional matrix adjust.
 Identities = 47/144 (32%), Positives = 77/144 (53%), Gaps = 5/144 (3%)
 Frame = -2

Query: 89  QERYRTITTAYYRGAMGFILMYDITNEESFNAVQDWS----TQIKTYSWDNAQVILAGNK 144
           QER++++  A+YRGA   IL+YD+T  ++F+++  W      Q      ++   ++ GNK
Sbjct: 577 QERFQSLGVAFYRGADCCILVYDVTEXKTFDSLDSWQREFLNQASPRDPEHFPFVVIGNK 398

Query: 145 CDMEDERVVSTERGQR-LGEQLGFEFFETSAKDNINVKQTFERLVDIICDKMSESLETDP 203
            D+ D RVV+ +RGQ     + G  +FETSAK+ INV+Q F+ +      K + + E++ 
Sbjct: 397 IDL-DNRVVTAKRGQGWCSTKGGIPYFETSAKEAINVEQAFQTVA-----KNALAQESEV 236

Query: 204 AITAAKQSTRLKETPPPPQPNCGC 227
            I       RL      P+  C C
Sbjct: 235 EIDDFPSEIRLSNDDSRPRERCAC 164
>34597
          Length = 773

 Score = 70.1 bits (170), Expect(2) = 4e-14,   Method: Compositional matrix adjust.
 Identities = 32/80 (40%), Positives = 49/80 (61%)
 Frame = -2

Query: 117 SFNAVQDWSTQIKTYSWDNAQVILAGNKCDMEDERVVSTERGQRLGEQLGFEFFETSAKD 176
           SF  +  W   I  ++ ++ + ++ GNKCDM D+RVVS ERG+ +  +    F ETSAK 
Sbjct: 709 SFENIVKWLRNIDEHANEDVEKMILGNKCDMTDKRVVSKERGEAIAREHSIRFMETSAKS 530

Query: 177 NINVKQTFERLVDIICDKMS 196
           NIN+++ F  L + I DK +
Sbjct: 529 NINIERAFCELAEAILDKTA 470

 Score = 24.3 bits (51), Expect(2) = 4e-14,   Method: Compositional matrix adjust.
 Identities = 9/13 (69%), Positives = 12/13 (92%)
 Frame = -3

Query: 97  TAYYRGAMGFILM 109
           T+YYRGAMG +L+
Sbjct: 771 TSYYRGAMGIMLV 733
>19006
          Length = 568

 Score = 71.2 bits (173), Expect = 3e-13,   Method: Compositional matrix adjust.
 Identities = 36/120 (30%), Positives = 67/120 (55%), Gaps = 1/120 (0%)
 Frame = -2

Query: 32  KLLIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVFKNEKRIKLQIWDTAGQER 91
           KL+I+G+ + GKT  L  ++ D F   +V TV  ++ V  +  + K+++L +WDTAGQE 
Sbjct: 432 KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENY-VADIEVDSKQVELALWDTAGQED 256

Query: 92  YRTITTAYYRGAMGFILMYDITNEESF-NAVQDWSTQIKTYSWDNAQVILAGNKCDMEDE 150
           Y  +    Y      ++ + I + +S  N  + W+ +++ +   N  +IL GNK D+ ++
Sbjct: 255 YDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVRHFC-PNVPIILVGNKKDLRND 79
>11728
          Length = 635

 Score = 68.9 bits (167), Expect = 1e-12,   Method: Compositional matrix adjust.
 Identities = 39/134 (29%), Positives = 68/134 (50%), Gaps = 2/134 (1%)
 Frame = -1

Query: 31  FKLLIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVFKNEKRIKLQIWDTAGQE 90
            K +++G+ +VGKT  L  Y  ++F   ++ TV  D     V  + K I L +WDTAGQE
Sbjct: 488 IKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTV-FDNYSANVMVDSKPINLGLWDTAGQE 312

Query: 91  RYRTITTAYYRGAMGFILMYDITNEESFNAVQ-DWSTQIKTYSWDNAQVILAGNKCDM-E 148
            Y  +    Y     F++ + + +  SF  V+  W  ++ ++   N  +IL G K D+ E
Sbjct: 311 DYDRLRPLSYPQTDVFLICFSLISPASFENVKAKWYPEV-SHHCPNTPIILVGTKLDLRE 135

Query: 149 DERVVSTERGQRLG 162
           D+  +   + ++L 
Sbjct: 134 DKETIEKLKEKKLA 93
>35581
          Length = 364

 Score = 64.7 bits (156), Expect = 3e-11,   Method: Compositional matrix adjust.
 Identities = 33/96 (34%), Positives = 56/96 (58%), Gaps = 1/96 (1%)
 Frame = +2

Query: 31  FKLLIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTV-FKNEKRIKLQIWDTAGQ 89
           FK +++G++ VGKT  L R A D F  + ++++     + TV   +     + +WDTAGQ
Sbjct: 47  FKCVLLGDAGVGKTCLLNRLATDKFLDSPLTSLTTASLLTTVTLTSGVMASVDLWDTAGQ 226

Query: 90  ERYRTITTAYYRGAMGFILMYDITNEESFNAVQDWS 125
           ERYR++T++YYR     +++YD    E    + DW+
Sbjct: 227 ERYRSLTSSYYRDTKAVLIVYD---AEHKLKLTDWT 325
>34359
          Length = 1042

 Score = 64.3 bits (155), Expect = 4e-11,   Method: Compositional matrix adjust.
 Identities = 32/122 (26%), Positives = 64/122 (52%)
 Frame = +3

Query: 31  FKLLIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVFKNEKRIKLQIWDTAGQE 90
           FKL+++G       + + R+   S    +V+T+G++        +   ++  +WDTAGQE
Sbjct: 54  FKLVLVGGRWEWANNIVKRHVTGS*-KKYVATLGVEVHPLQFNTSRGLLRFNVWDTAGQE 230

Query: 91  RYRTITTAYYRGAMGFILMYDITNEESFNAVQDWSTQIKTYSWDNAQVILAGNKCDMEDE 150
           ++  +   YY      I+M+D+T+  ++  V +W   +     +N  ++L GNK D++D 
Sbjct: 231 KFGGLRDGYYIQGTCAIIMFDVTSRVTYKNVPNWHRDLVRVC-ENIPIVLCGNKVDIKDR 407

Query: 151 RV 152
           +V
Sbjct: 408 KV 413
>13745
          Length = 1045

 Score = 62.8 bits (151), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 37/115 (32%), Positives = 63/115 (54%), Gaps = 5/115 (4%)
 Frame = +2

Query: 89  QERYRTITTAYYRGAMGFILMYDITNEESFNAVQDWS----TQIKTYSWDNAQVILAGNK 144
           QER++++  A+YRGA   +L+YD+T   SF  +  W      Q      ++   ++ GNK
Sbjct: 2   QERFQSLGVAFYRGADCCVLVYDVTAPNSFKNLDSWRDEFLIQASPRDPEHFPFVVLGNK 181

Query: 145 CDMEDERVVSTERGQRLGEQLG-FEFFETSAKDNINVKQTFERLVDIICDKMSES 198
            D+ D R VST R Q+  +      ++ETSAK+ INV+  F+ +     ++ +E+
Sbjct: 182 VDL-DNRQVSTRRAQQWCQSKNDIPYYETSAKEGINVEMAFQTIAKNALEQETEA 343
>19046
          Length = 445

 Score = 62.4 bits (150), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 36/105 (34%), Positives = 59/105 (56%), Gaps = 2/105 (1%)
 Frame = -2

Query: 89  QERYRTITTAYYRGAMGFILMYDITNEESFNAVQDWSTQI-KTYSWDNAQVILAGNKCDM 147
           QE +  +   Y R   GF+L++ +T+  SF  + ++ TQI +    D+  +IL  NK D+
Sbjct: 444 QEEFSAMREQYMRKGDGFLLVFSVTDFRSFENMANFHTQILRVKDRDSYPMILCANKVDL 265

Query: 148 EDERVVSTERGQRLGEQLGFEFFETSAKD-NINVKQTFERLVDII 191
             +R VS E+ + L  +L   + ETSAKD  +NV   F ++V +I
Sbjct: 264 VHQRKVSEEQVRDLATRLRIPYIETSAKDPPLNVDLAFHQVVRVI 130
>24619
          Length = 509

 Score = 60.5 bits (145), Expect = 5e-10,   Method: Compositional matrix adjust.
 Identities = 35/105 (33%), Positives = 58/105 (55%), Gaps = 2/105 (1%)
 Frame = -2

Query: 89  QERYRTITTAYYRGAMGFILMYDITNEESFNAVQDWSTQI-KTYSWDNAQVILAGNKCDM 147
           QE +  +   Y R   GF+L++ + + +SF  + ++ TQI +    D   +IL  NK D+
Sbjct: 508 QEEFSAMREQYMRKGDGFLLVFSVIDYQSFENMVNFHTQILRVKDRDTYPMILCANKVDL 329

Query: 148 EDERVVSTERGQRLGEQLGFEFFETSAKD-NINVKQTFERLVDII 191
             +R VS E+ + L  +L   + ETSAKD  +NV   F ++V +I
Sbjct: 328 VHQRKVSEEQVRDLATRLRIPYIETSAKDPPLNVDLAFHQVVRVI 194
>01095
          Length = 1745

 Score = 59.3 bits (142), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 28/77 (36%), Positives = 45/77 (58%)
 Frame = -1

Query: 108  LMYDITNEESFNAVQDWSTQIKTYSWDNAQVILAGNKCDMEDERVVSTERGQRLGEQLGF 167
            ++YDITN+++F   + W  +++  +  N  + LAGNK D+ ++R+V  E  Q   E+   
Sbjct: 1745 VVYDITNQDTFGRAKTWVKELQRQASPNIVIALAGNKADLANKRMVEFEEAQAYAEENSL 1566

Query: 168  EFFETSAKDNINVKQTF 184
             F ETSAK  +NV   F
Sbjct: 1565 LFMETSAKTAMNVNDIF 1515
>27191
          Length = 443

 Score = 57.4 bits (137), Expect = 4e-09,   Method: Compositional matrix adjust.
 Identities = 27/104 (25%), Positives = 54/104 (51%), Gaps = 2/104 (1%)
 Frame = +1

Query: 43  KTSFLFRYADDSFTSAFVSTVGID--FKVKTVFKNEKRIKLQIWDTAGQERYRTITTAYY 100
           KT  +  + +  F   +  TVG+D  FK++TV  N   +++ +WD +G   Y  +    Y
Sbjct: 1   KTCLIKHFCESKFNQGYQPTVGVDYGFKIQTV--NGVDMRVHMWDLSGSNEYLDVRNELY 174

Query: 101 RGAMGFILMYDITNEESFNAVQDWSTQIKTYSWDNAQVILAGNK 144
            G+    +++D++N  SF A+  W  +I  ++  +   ++ GN+
Sbjct: 175 TGSDAIFIVFDVSNTPSFEALDSWLREINRFATGSPLNVIVGNR 306
>00858
          Length = 1658

 Score = 56.6 bits (135), Expect = 7e-09,   Method: Compositional matrix adjust.
 Identities = 46/159 (28%), Positives = 73/159 (45%), Gaps = 1/159 (0%)
 Frame = -2

Query: 31   FKLLIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVFKNEKRIKLQIWDTAGQE 90
            +KL+++G   VGK++   +   + F   +  T     + + V   E  + L I DTAGQE
Sbjct: 1588 YKLVVVGAGGVGKSALTIQLXQNHFVEEYDPTXEDSXRKQVVIDGETCL-LDILDTAGQE 1412

Query: 91   RYRTITTAYYRGAMGFILMYDITNEESFNAVQDWSTQIK-TYSWDNAQVILAGNKCDMED 149
                +     R   GF+ ++ + N +SF  +  +  QIK     D   ++L GNK D+  
Sbjct: 1411 EXSAMRDQCMRTGEGFLCVFAVXNLKSFEDINQYREQIKRVKDADEVPMVLVGNKVDLPI 1232

Query: 150  ERVVSTERGQRLGEQLGFEFFETSAKDNINVKQTFERLV 188
             R V   +G+ + E     + ETSAK    V   F  LV
Sbjct: 1231 -RNVEQRQGKHMAELYHIPYVETSAKTRQGVDDAFYTLV 1118
>19656
          Length = 428

 Score = 56.2 bits (134), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 28/102 (27%), Positives = 51/102 (50%), Gaps = 1/102 (0%)
 Frame = +3

Query: 31  FKLLIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVFKNEKRIKLQIWDTAGQE 90
            K +++G+ +VGKT  L  Y  ++F   ++ TV  D     V  + + + L +WDTAGQE
Sbjct: 114 IKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTV-FDNYSANVMVDGRPVNLGLWDTAGQE 290

Query: 91  RYRTITTAYYRGAMGFILMYDITNEESFNAVQ-DWSTQIKTY 131
            Y  +    Y     F+L + + +  SF  ++  W  ++  +
Sbjct: 291 DYDRLRPLSYPQTDVFLLCFSVASPASFENIRAKWYPEVNHH 416
>31291
          Length = 446

 Score = 53.5 bits (127), Expect = 6e-08,   Method: Compositional matrix adjust.
 Identities = 35/124 (28%), Positives = 59/124 (47%), Gaps = 14/124 (11%)
 Frame = -1

Query: 81  LQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEESFNAVQ-DWSTQIKTYSWDNAQVI 139
           LQ+WDTAGQE Y  +    Y     F+L + + +E S   V+  W  +I+ +   +  ++
Sbjct: 446 LQLWDTAGQEDYDRLRPLAYPNTDVFMLXFSLMSEASMKNVKVKWYPEIRHHD-PHVPIV 270

Query: 140 LAGNKCDMEDER------------VVSTERGQRLGEQL-GFEFFETSAKDNINVKQTFER 186
           L G K D+  ++             VS+ +G  L + +    +FE S+K   N+K  FE 
Sbjct: 269 LVGTKLDLRQDKEAVRKLRSSRQDPVSSNQGNDLAKAIKAKRYFECSSKTQENLKTAFEE 90

Query: 187 LVDI 190
            V +
Sbjct: 89  TVRV 78
>09204
          Length = 1051

 Score = 51.6 bits (122), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 29/113 (25%), Positives = 59/113 (52%), Gaps = 4/113 (3%)
 Frame = -3

Query: 91   RYRTITTAYYRGAMGFILMYDITNEESFNAVQDWSTQIKTYSWDNAQVILAGNKCDM--- 147
            RY  ++  YYRGA   IL +D+T++ SF+ ++ W  +++ +  +  ++ + G K D+   
Sbjct: 1049 RYEAMSRIYYRGAKAAILCFDLTDKSSFDRIRFWIGELRQHE-EECKLYICGTKFDLVHD 873

Query: 148  -EDERVVSTERGQRLGEQLGFEFFETSAKDNINVKQTFERLVDIICDKMSESL 199
              + R V     + L +    E +ETS+    N+++ F ++ +   D M E +
Sbjct: 872  DPERRAVPRSVAKALADDCMAEIYETSSMTGDNIEKLFTKIAE---DYMKERI 723
>00552
          Length = 455

 Score = 49.7 bits (117), Expect = 9e-07,   Method: Compositional matrix adjust.
 Identities = 20/49 (40%), Positives = 31/49 (63%)
 Frame = -3

Query: 83  IWDTAGQERYRTITTAYYRGAMGFILMYDITNEESFNAVQDWSTQIKTY 131
           IWDTAGQERY+++ T +YRG    +L + + N +S  ++ DW  +   Y
Sbjct: 147 IWDTAGQERYKSLRTPFYRGTDCCLLTFSVDNLKSLQSLSDWYDEFVNY 1

 Score = 33.9 bits (76), Expect = 0.053,   Method: Compositional matrix adjust.
 Identities = 13/43 (30%), Positives = 27/43 (62%)
 Frame = -1

Query: 30  MFKLLIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTV 72
           + K++++G+  VGK+S + R+  + F +    T+G++F  K V
Sbjct: 446 LLKVVLLGDGGVGKSSLMNRFVSNKFDAQSFHTIGVEFLTKDV 318
>14775
          Length = 380

 Score = 49.3 bits (116), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 40/154 (25%), Positives = 60/154 (38%), Gaps = 5/154 (3%)
 Frame = -2

Query: 43  KTSFLFRYADDSFTSAFVSTVGIDFKVKTVFKNEKR-----IKLQIWDTAGQERYRTITT 97
           KT  L RY    F    + T+ +   + + F NE R     ++  +WDT G E YR++  
Sbjct: 379 KTCLLRRYQKGFFMDRTMPTIAV---LCSEF-NESRTDPLNVRYTLWDTGGAETYRSLWV 212

Query: 98  AYYRGAMGFILMYDITNEESFNAVQDWSTQIKTYSWDNAQVILAGNKCDMEDERVVSTER 157
           +++RGA   +L+YD+T                                          ER
Sbjct: 211 SHFRGAQVALLVYDVT-----------------------------------------CER 155

Query: 158 GQRLGEQLGFEFFETSAKDNINVKQTFERLVDII 191
           GQ    Q G+ FFETS+    NV   F  +  I+
Sbjct: 154 GQAFATQCGYTFFETSSVTGKNVDAVFWEIAFIL 53
>29380
          Length = 853

 Score = 48.5 bits (114), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 26/84 (30%), Positives = 45/84 (53%), Gaps = 1/84 (1%)
 Frame = -2

Query: 107 ILMYDITNEESFNAVQDWSTQIKTYSWDNAQVILAGNKCDMEDE-RVVSTERGQRLGEQL 165
           I++YD+   ++F+    W  +++  + ++  +ILAGNK D+  + R VS E  Q    + 
Sbjct: 840 IIVYDVNIADTFSRALAWVKELRQQNTESVLIILAGNKVDLATQHRAVSFEDAQSFAREN 661

Query: 166 GFEFFETSAKDNINVKQTFERLVD 189
           G  F E SAK  + V + F  L +
Sbjct: 660 GLLFAEVSAKTGMAVNEIFMTLAN 589
>09827
          Length = 1201

 Score = 47.8 bits (112), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 36/147 (24%), Positives = 71/147 (48%), Gaps = 1/147 (0%)
 Frame = -3

Query: 17   FGQKDSSDQNFDYMFKLLIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVFKNE 76
            FG+KD          ++L++G  + GKT+ L++       +  + T+G  F V+TV    
Sbjct: 1127 FGKKD---------MRILMVGLDAAGKTTILYKLKLGEIVTT-IPTIG--FNVETV--EY 990

Query: 77   KRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEESFN-AVQDWSTQIKTYSWDN 135
            K I   +WD  GQ++ R +   Y++   G I + D  ++E    A ++ +  +      +
Sbjct: 989  KNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDKERVQEAREELTRMLNEDELRD 810

Query: 136  AQVILAGNKCDMEDERVVSTERGQRLG 162
            A +++  NK D+    + + E  ++LG
Sbjct: 809  AVLLVFANKQDLP-HAMATAEITEKLG 732
>08153
          Length = 1703

 Score = 47.8 bits (112), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 30/117 (25%), Positives = 59/117 (50%), Gaps = 1/117 (0%)
 Frame = +1

Query: 32  KLLIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVFKNEKRIKLQIWDTAGQER 91
           ++L++G  + GKT+ L++       +  + T+G  F V+TV    K I   +WD  GQ++
Sbjct: 88  RILMVGLDAAGKTTILYKLKLGEIVTT-IPTIG--FNVETV--EYKNISFTVWDVGGQDK 252

Query: 92  YRTITTAYYRGAMGFILMYDITNEESFN-AVQDWSTQIKTYSWDNAQVILAGNKCDM 147
            R +   Y++   G I + D  + E  N A ++ +  +      +A +++  NK D+
Sbjct: 253 IRPLWRHYFQNTQGLIFVVDSNDRERINEAKEELARMLNEDDLRDAIILVFANKQDL 423
>14119
          Length = 602

 Score = 41.6 bits (96), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 22/69 (31%), Positives = 35/69 (50%), Gaps = 1/69 (1%)
 Frame = +1

Query: 117 SFNAVQDWSTQIKTYSWDNAQVILAGNKCDMEDE-RVVSTERGQRLGEQLGFEFFETSAK 175
           +FN    W  +++  +  +  ++LAGNK D+  E R VS +  +   E  G  F E SAK
Sbjct: 1   TFNRALAWVKELRQQNAGSVLIVLAGNKADLASEHRAVSADDARTFAEDNGLIFAEVSAK 180

Query: 176 DNINVKQTF 184
             + V + F
Sbjct: 181 TGMAVSEVF 207
>10862
          Length = 2896

 Score = 38.1 bits (87), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 19/71 (26%), Positives = 34/71 (47%), Gaps = 1/71 (1%)
 Frame = -3

Query: 80   KLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEESFN-AVQDWSTQIKTYSWDNAQV 138
            +  +WD  GQ++ R +   YY G  G I + D  + +  + A Q+    I      +A +
Sbjct: 2483 QFNVWDVGGQDKIRPLWRHYYTGTQGLIFVVDCADRDRIDEARQELHRIINDREMRDAII 2304

Query: 139  ILAGNKCDMED 149
            ++  NK D+ D
Sbjct: 2303 LIFANKQDLPD 2271
>33605
          Length = 888

 Score = 37.4 bits (85), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 22/80 (27%), Positives = 41/80 (51%)
 Frame = +1

Query: 32  KLLIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVFKNEKRIKLQIWDTAGQER 91
           +LL++G  + GKT+ L ++  +   +    T+G  F +KT+    +  KL +WD  GQ+ 
Sbjct: 502 RLLMLGLDNAGKTTILKKFNGEDIDT-ISPTLG--FNIKTL--EHRGFKLNVWDVGGQQS 666

Query: 92  YRTITTAYYRGAMGFILMYD 111
            R+    Y+    G + + D
Sbjct: 667 LRSYWRNYFESTDGLVWVVD 726
>25796
          Length = 422

 Score = 32.0 bits (71), Expect = 0.23,   Method: Compositional matrix adjust.
 Identities = 11/33 (33%), Positives = 21/33 (63%)
 Frame = -1

Query: 18  GQKDSSDQNFDYMFKLLIIGNSSVGKTSFLFRY 50
            + ++  + +DY+FK LIIG++  GK+  L  +
Sbjct: 104 AKTNNMSETYDYLFKFLIIGSAGSGKSCLLHHF 6
>10708
          Length = 2775

 Score = 31.2 bits (69), Expect = 0.39,   Method: Compositional matrix adjust.
 Identities = 12/45 (26%), Positives = 24/45 (53%)
 Frame = -2

Query: 77   KRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEESFNAV 121
            ++++L +WDTAGQE Y  +    Y      ++ + I + +S   +
Sbjct: 2729 QQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENI 2595
>06994
          Length = 429

 Score = 28.9 bits (63), Expect = 1.9,   Method: Compositional matrix adjust.
 Identities = 11/34 (32%), Positives = 20/34 (58%)
 Frame = +1

Query: 90  ERYRTITTAYYRGAMGFILMYDITNEESFNAVQD 123
           E++  +   Y +   GF+L Y IT + +FN +Q+
Sbjct: 328 EQFTAMRDLYMKNGQGFLLAYSITAQSTFNDLQE 429
>18184
          Length = 558

 Score = 28.5 bits (62), Expect = 2.2,   Method: Compositional matrix adjust.
 Identities = 13/36 (36%), Positives = 20/36 (55%)
 Frame = -3

Query: 29  YMFKLLIIGNSSVGKTSFLFRYADDSFTSAFVSTVG 64
           Y+F +L+ G    G    +  +  +SF + FVSTVG
Sbjct: 442 YLFYILLTGIVQFGYCCLVGTFPFNSFLAGFVSTVG 335
>07531
          Length = 2059

 Score = 28.1 bits (61), Expect = 2.8,   Method: Compositional matrix adjust.
 Identities = 11/29 (37%), Positives = 19/29 (65%)
 Frame = -1

Query: 7   MQMASAQDARFGQKDSSDQNFDYMFKLLI 35
           +Q+A+A + R  + D   +N  +MF+LLI
Sbjct: 721 IQVAAAVETRAQKXDEKKKNLTWMFRLLI 635
>31932
          Length = 437

 Score = 27.7 bits (60), Expect = 4.4,   Method: Compositional matrix adjust.
 Identities = 23/107 (21%), Positives = 40/107 (37%), Gaps = 3/107 (2%)
 Frame = -1

Query: 124 WSTQIKTYSWDNAQVILAGNKCDMEDERVVSTERGQRLGEQLGFEFFETSAKDNINVKQT 183
           W+  +          +L GNK D+    V   E      E     + ETS KD   + ++
Sbjct: 437 WTASVNWPYGSTVPCLLLGNKSDLGHREVEQDEIEDLCKEHDFLGWSETSVKDGTMIDES 258

Query: 184 FERLVDIICDKMSESLETDPAITAAKQSTR---LKETPPPPQPNCGC 227
              L++ +  K +E      ++T      R    +++  P    CGC
Sbjct: 257 MNYLIEEMMAKHAELEGFSESVTQGNGVIRRLSREDSDVPSGSRCGC 117
>31928
          Length = 429

 Score = 27.3 bits (59), Expect = 4.6,   Method: Compositional matrix adjust.
 Identities = 21/69 (30%), Positives = 31/69 (44%), Gaps = 4/69 (5%)
 Frame = +2

Query: 80  KLQIWDTAGQERYRT---ITTAYYRGAMGFILMYDITNEESFNAVQDWSTQI-KTYSWDN 135
           K++I+DT       T   +   Y     GF+L+YD T+ ESF  +      I K      
Sbjct: 107 KVRIFDTGAAALETTEGDLPKHYLNFPDGFVLVYDTTSWESFRRLDKLKKDIDKHRDKRE 286

Query: 136 AQVILAGNK 144
             +I+ GNK
Sbjct: 287 VHMIVIGNK 313
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|7305095|ref|NP_038775.1| golgi autoantigen, golgin
subfamily a, 5 [Mus musculus]
         (729 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

21297                                                                 171   9e-43
19058                                                                  96   3e-20
30332                                                                  31   1.7  
>21297
          Length = 550

 Score =  171 bits (433), Expect = 9e-43,   Method: Compositional matrix adjust.
 Identities = 99/175 (56%), Positives = 128/175 (73%), Gaps = 5/175 (2%)
 Frame = -1

Query: 555 QSRIKDREEEIQKLRNQLTNKTLSNSSQSELESRLHQLTETLIQKQTMLESLSTEKNSLV 614
           Q+RI DRE EI KLRNQLT K++S++S+SELESR+  LTE+LIQKQTMLE+LSTEKNSL 
Sbjct: 550 QTRITDRETEIDKLRNQLTTKSISSTSESELESRVRSLTESLIQKQTMLEALSTEKNSLT 371

Query: 615 FQLERLEQQVHSASSGPNSGSAINMSGVDSGEGTRLRNVPVLFN----DTETNLAGMYGK 670
            QLERL QQ     +     +A +++  D+ +  R R +P        DTE        +
Sbjct: 370 LQLERLGQQYRDVETSLMRSTATSVNVGDTDDDLRQR-LPTFMKEGVADTEVT-----KR 209

Query: 671 VRKAASSIDQFSIRLGIFLRRYPIARVFVIIYMALLHLWVMIVLLTYSPEMH-HD 724
           V++  ++ID+FSIRLG+FLRRYPIAR+FVI+YMA+LHLWVM+VL+TY PEMH HD
Sbjct: 208 VKRYVNTIDKFSIRLGVFLRRYPIARIFVIVYMAMLHLWVMVVLMTYQPEMHGHD 44
>19058
          Length = 421

 Score = 96.3 bits (238), Expect = 3e-20,   Method: Compositional matrix adjust.
 Identities = 58/131 (44%), Positives = 94/131 (71%)
 Frame = +1

Query: 352 LHEADATLKREQESYKQMQSEFAARLNKMEVDRQNLAEAVTLAERKYSEEKKKVDELQQQ 411
           L + +A L RE++  K ++ E A R +++E + ++LAEA+T+AERK +EE+ K  E   Q
Sbjct: 1   LVDMEALLTREKQILKDVEQEAAERQSRLEQEEKSLAEALTVAERKITEERAKGAEALGQ 180

Query: 412 VKLHRASLESAKQELVDYKQKATRILQSKEKLINSLKEGSSFEGLESSTASSMELEELRH 471
           +K  +A+L S +QE+++YK+KA+RILQSKE+LI+SL++GS   G      SS+E E ++ 
Sbjct: 181 LKTLKATLASTQQEMMEYKEKASRILQSKERLISSLRDGSGASG-SVDGVSSLEYESVQQ 357

Query: 472 EKEMQKEEIQK 482
           E++M +EE+QK
Sbjct: 358 ERDMLREELQK 390
>30332
          Length = 401

 Score = 31.2 bits (69), Expect = 1.7,   Method: Compositional matrix adjust.
 Identities = 34/119 (28%), Positives = 70/119 (58%), Gaps = 11/119 (9%)
 Frame = +2

Query: 484 MGQMHQLRSELQDMEAQQVSEAESAREQLQDLQDQIAKQRTSKQELETELERMKQEFRYM 543
           M Q+ Q+++EL+D+E ++  +       L+D+   IAK+ T  ++L+++++ ++Q  + +
Sbjct: 2   MDQLAQVKAELKDLERKRNKQERL----LKDINQVIAKKDTEFRDLDSKVKAVQQSLQRV 169

Query: 544 EEDL----HRTKNTLQSRIKDREE-------EIQKLRNQLTNKTLSNSSQSELESRLHQ 591
           +EDL     R K T+ + ++D E+       EI ++R+Q+      +S ++ELE RL Q
Sbjct: 170 QEDLALSTQREKETVDA-LRDSEDILGKRRAEIARMRDQV------DSQRAELE-RLDQ 322
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6679465|ref|NP_032951.1| protein kinase C substrate
80K-H [Mus musculus]
         (521 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

01041                                                                 170   1e-42
18588                                                                 136   3e-32
04968                                                                 106   2e-23
27664                                                                  32   0.50 
08380                                                                  31   1.1  
30369                                                                  29   4.5  
36074                                                                  28   6.3  
>01041
          Length = 1761

 Score =  170 bits (430), Expect = 1e-42,   Method: Compositional matrix adjust.
 Identities = 75/154 (48%), Positives = 98/154 (63%)
 Frame = -3

Query: 348 KMPPYDEETQAIIDAAQEARSKFEEVERSLKEMEESIRSLEQEISFDFGPSGEFAYLYSQ 407
            MP YD +TQ +ID A   R ++ +V+ S++  E  I  L++ +  D+GP  E++ L SQ
Sbjct: 946 NMPXYDADTQKLIDEADAVRXQYNDVDSSVRNAENEISGLKKYLEVDYGPEEEYSSLRSQ 767

Query: 408 CYELTTNEYVYRLCPFKLVSQKPKHGGSPTSLGTWGSWAGPDHDKFSAMKYEQGTGCWQG 467
           C+E T  EY Y+LCPF   SQ+PK GG  TSLG WG W GP+ DK+ AMKYE G  CW G
Sbjct: 766 CFEFTDREYTYKLCPFDKTSQRPKAGGVETSLGKWGHWYGPEEDKYDAMKYENGQSCWNG 587

Query: 468 PNRSTTVRLLCGKETVVTSTTEPSRCEYLMELMT 501
           P+RS  + L CG E  +T  +EPSRCEY  E  T
Sbjct: 586 PSRSCHINLHCGTENKLTGASEPSRCEYQFEFTT 485

 Score = 61.2 bits (147), Expect = 9e-10,   Method: Compositional matrix adjust.
 Identities = 49/186 (26%), Positives = 74/186 (39%), Gaps = 15/186 (8%)
 Frame = -3

Query: 112  CENTCREKGRKEKESLQQLA---------------EVTREGFRLKKILIEEWKTAREEKQ 156
            C NTC E GR+E+E  +Q A               + +  G +  K +       R    
Sbjct: 1726 CVNTCNEMGRQEREEREQFACYKSKDTGSNRSTCSKASEPGMKTGKTVGTXAADVRPAGN 1547

Query: 157  SKLLELQAGKKSLEDQVETLXXXXXXXXXXXXXXXDQHRKLWXXXXXXXXXXXXXXXXXX 216
                  +A +K  +D+VE                 ++H+K W                  
Sbjct: 1546 P*----RAXEK--KDEVEI----------PEKEAKEKHQKAWEELKAERQAQLDKAQAVV 1415

Query: 217  XXXXLDDNMDGMVSLAELQTHPELDTDGDGALSEEEAQALLSGDTQTDTTSFYDRVWAAI 276
                LD N D +V   E+Q H E D D DG +SE+EA+  L  +   D  +F DR++A I
Sbjct: 1414 VFEELDVNSDSVVDFIEMQRHLEFDIDSDGTVSEDEAREYLEDNEGVDLETFQDRIYANI 1235

Query: 277  RDKYRS 282
            +D Y+S
Sbjct: 1234 KDIYKS 1217
>18588
          Length = 453

 Score =  136 bits (342), Expect = 3e-32,   Method: Compositional matrix adjust.
 Identities = 60/120 (50%), Positives = 85/120 (70%)
 Frame = -1

Query: 21  RGVSLSNHHFYEESKPFTCLDGTATIPFDQVNDDYCDCKDGSDEPGTAACPNGSFHCTNT 80
           RG+  S    Y+  K FTC+    T+P++ VNDDYCDCKDG+DEPGT+AC NG F+C N 
Sbjct: 357 RGI-FSKGFIYQPGKEFTCITSGETVPWEFVNDDYCDCKDGTDEPGTSACTNGFFYCENR 181

Query: 81  GYKPLYILSSRVNDGVCDCCDGTDEYNSGTVCENTCREKGRKEKESLQQLAEVTREGFRL 140
           GY+   ++SSRVNDG+CDCCDG+DE+     C NTC E G+KE+E ++   ++  +G+++
Sbjct: 180 GYRGSNLISSRVNDGICDCCDGSDEFEERIKCVNTCNELGKKEQEDMKVFQQLQEQGYKV 1
>04968
          Length = 704

 Score =  106 bits (265), Expect = 2e-23,   Method: Compositional matrix adjust.
 Identities = 47/101 (46%), Positives = 65/101 (64%)
 Frame = +2

Query: 349 MPPYDEETQAIIDAAQEARSKFEEVERSLKEMEESIRSLEQEISFDFGPSGEFAYLYSQC 408
           MP YD +TQ +ID A   R ++ +V+ S++  E  I  L++ +  D+GP  E++ L SQC
Sbjct: 398 MPVYDADTQKLIDEADAVRKQYNDVDSSVRNAENEISGLKKYLEVDYGPEEEYSSLRSQC 577

Query: 409 YELTTNEYVYRLCPFKLVSQKPKHGGSPTSLGTWGSWAGPD 449
           +E T  EY Y+LCPF   SQ+PK GG  TSLG WG W GP+
Sbjct: 578 FEFTDREYTYKLCPFDKTSQRPKAGGVETSLGKWGHWYGPE 700
>27664
          Length = 1281

 Score = 32.3 bits (72), Expect = 0.50,   Method: Compositional matrix adjust.
 Identities = 26/67 (38%), Positives = 35/67 (52%)
 Frame = +3

Query: 69  ACPNGSFHCTNTGYKPLYILSSRVNDGVCDCCDGTDEYNSGTVCENTCREKGRKEKESLQ 128
           AC +GSF C  TG     + +SR  DG  DC DG+DE N    C + C+   R  +E+L 
Sbjct: 48  ACSSGSFQCA-TGQ---CVQASRTCDGTEDCTDGSDEIN----CPSQCKGMLRGPEETL- 200

Query: 129 QLAEVTR 135
               +TR
Sbjct: 201 -CXRITR 218
>08380
          Length = 1236

 Score = 31.2 bits (69), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 15/46 (32%), Positives = 28/46 (60%), Gaps = 1/46 (2%)
 Frame = -1

Query: 240 LDTDGDGALSEEEAQALLSGDTQTDTTSFYDRVWAAIR-DKYRSEV 284
           +DT+GDG ++EEE  AL  G+ + +     D+ W   R +++R+ +
Sbjct: 453 IDTNGDGVVTEEEFSALPPGEVEGEEYQAMDKQWQKERQEEFRTAI 316
>30369
          Length = 348

 Score = 29.3 bits (64), Expect = 4.5,   Method: Compositional matrix adjust.
 Identities = 20/51 (39%), Positives = 23/51 (45%)
 Frame = -3

Query: 57  DCKDGSDEPGTAACPNGSFHCTNTGYKPLYILSSRVNDGVCDCCDGTDEYN 107
           DC+D SDE     C +  F C         +      DG  DC DGTDEYN
Sbjct: 277 DCQDASDEEYCTGCSDDQFTC----LSGQCVERRNRCDGHVDCVDGTDEYN 137
>36074
          Length = 478

 Score = 28.5 bits (62), Expect = 6.3,   Method: Compositional matrix adjust.
 Identities = 19/52 (36%), Positives = 20/52 (38%), Gaps = 1/52 (1%)
 Frame = +3

Query: 37 FTCLDGTATIPFDQVNDDYCDCKDGSDEPGTA-ACPNGSFHCTNTGYKPLYI 87
          FTC      IP  +  D   DC DGSDE      C  G   C      P YI
Sbjct: 39 FTCETSRDCIPASRRCDRRSDCDDGSDERDCGPVCSEGELECDGRCLPPQYI 194
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|118026911|ref|NP_796364.2| myosin ID [Mus musculus]
         (1006 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

25922                                                                 170   2e-42
01284                                                                  50   3e-06
30605                                                                  39   0.010
28295                                                                  29   8.4  
>25922
          Length = 422

 Score =  170 bits (431), Expect = 2e-42,   Method: Compositional matrix adjust.
 Identities = 79/143 (55%), Positives = 104/143 (72%)
 Frame = -2

Query: 309 DMVEKALLYRTVATGRDIIDKQHTEQEASYGRDAFAKAIYERLFCWIVTRINDIIEVKNY 368
           D +  AL++RTVA   D++    +  E+SY RDA  KA+Y R+F W+V RIND I+V+  
Sbjct: 415 DTLAHALMHRTVAVKGDMVTTDLSVSESSYARDALCKALYSRMFSWLVHRINDSIKVRGA 236

Query: 369 DTTIHGKNTVIGVLDIYGFEIFDNNSFEQFCINYCNEKLQQLFIQLVLKQEQEEYQREGI 428
             T      V+GVLDIYGFE+F+NNSFEQF INYCNEKLQQ+FI+L LK+EQEEY +EGI
Sbjct: 235 QRT-----KVMGVLDIYGFEVFENNSFEQFIINYCNEKLQQIFIELTLKEEQEEYIKEGI 71

Query: 429 PWKHIDYFNNQIIVDLVEQQHKG 451
            W H++YFNN +I +L+E+   G
Sbjct: 70  EWIHVEYFNNAVICELIEKSVSG 2
>01284
          Length = 1603

 Score = 50.4 bits (119), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 31/122 (25%), Positives = 57/122 (46%), Gaps = 1/122 (0%)
 Frame = +2

Query: 562 LTAATLFKNSMIALVDNLASKEPYYVRCIKPNDKKSPQIFDDERCRHQVEYLGLLENVRV 621
           ++  T F+  ++ L+D L S    ++RCIKPN K    +F+      Q++  G++  + +
Sbjct: 14  ISVGTKFRKQLLVLMDKLKSTGTNFIRCIKPNVKMVDHLFEGANILSQLQCAGMVSVLEL 193

Query: 622 RRAGFAFRQTYEKFLHRYKMISEFTWPNHDLPSDKEAVKKLIERCGFQD-DVAYGKSKIF 680
            + GF  R  + +    Y M  ++  P       +   K L +  G  D D  +G +K+F
Sbjct: 194 MQQGFPSRTPFSEL---YNMYKKYLPPELSRLDPRLFCKSLFKALGLDDKDFKFGLTKVF 364

Query: 681 IR 682
            R
Sbjct: 365 FR 370
>30605
          Length = 336

 Score = 38.9 bits (89), Expect = 0.010,   Method: Composition-based stats.
 Identities = 31/111 (27%), Positives = 49/111 (44%), Gaps = 9/111 (8%)
 Frame = -3

Query: 241 INDAAEFKVVADAMKVIGFKPEEIQTVYKILAVILHLGNLKFIVDGDTP------LIENG 294
           ++D  +FKV  +AM  +G    +   ++ ++A +LHLGN+ F  D D        L E  
Sbjct: 334 LDDVRDFKVCDEAMTRMGVSDADKMAIFMLVAAVLHLGNIAFEDDHDDTKGGCKVLEEAE 155

Query: 295 KVVSVIAELLSTKADMVEKALLYRTVATG---RDIIDKQHTEQEASYGRDA 342
             ++  A LL      +  +L  R + +G      I       EAS  RDA
Sbjct: 154 DSLATAAVLLGVDKMELRDSLTSRIMQSGGIKGSAIKVPLKPSEASSARDA 2
>28295
          Length = 502

 Score = 29.3 bits (64), Expect = 8.4,   Method: Compositional matrix adjust.
 Identities = 12/53 (22%), Positives = 28/53 (52%)
 Frame = -3

Query: 762 WPTPPKVLRRFEEALQSIFNRWRASQLIKTIPASDLPQVRAKVAAMEMLKGQR 814
           WP  P       + L+++F+RWR ++  +   +    ++R K+ A ++ K ++
Sbjct: 173 WPAAPSRFNATSQELKTLFHRWRCAKYRQRFDSKAQHRMREKLTASDLFKDKK 15
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|11612509|ref|NP_071722.1| v-ral simian leukemia viral
oncogene homolog B (ras related) [Mus musculus]
         (206 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

07580                                                                 151   4e-42
00858                                                                 151   2e-37
19046                                                                  93   7e-20
24619                                                                  92   1e-19
26536                                                                  92   2e-19
14456                                                                  90   8e-19
08428                                                                  89   1e-18
11257                                                                  82   1e-16
11728                                                                  80   6e-16
34468                                                                  80   7e-16
17511                                                                  78   2e-15
30760                                                                  78   3e-15
36482                                                                  77   4e-15
19006                                                                  77   4e-15
06994                                                                  59   6e-15
33374                                                                  76   9e-15
19656                                                                  74   5e-14
07465                                                                  72   2e-13
18509                                                                  59   3e-12
13750                                                                  67   4e-12
01972                                                                  64   4e-11
01398                                                                  64   4e-11
26083                                                                  64   5e-11
33380                                                                  62   2e-10
33794                                                                  62   2e-10
34359                                                                  55   3e-10
05468                                                                  58   3e-09
32723                                                                  58   3e-09
01095                                                                  54   6e-08
13901                                                                  52   2e-07
17872                                                                  51   4e-07
35581                                                                  49   1e-06
09204                                                                  49   2e-06
31291                                                                  48   3e-06
34597                                                                  41   3e-04
00552                                                                  37   0.005
09827                                                                  37   0.005
08153                                                                  37   0.005
10708                                                                  35   0.027
31932                                                                  32   0.17 
33605                                                                  30   0.74 
14775                                                                  29   1.3  
31928                                                                  29   1.5  
22274                                                                  28   3.0  
31774                                                                  27   4.9  
10824                                                                  27   7.4  
>07580
          Length = 921

 Score =  151 bits (382), Expect(2) = 4e-42,   Method: Compositional matrix adjust.
 Identities = 72/141 (51%), Positives = 101/141 (71%)
 Frame = +3

Query: 39  FVEDYEPTKADSYRKKVVLDGEEVQIDILDTAGQEDYAAIRDNYFRSGEGFLLVFSITEH 98
           FVE Y+PT  DSYRK+V +DG++  ++ILDTAG E + A+RD Y ++G+GFLL +SIT  
Sbjct: 135 FVEKYDPTIEDSYRKQVEVDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFLLAYSITAQ 314

Query: 99  ESFTATAEFREQILRVKSEEDKIPLLVVGNKSDLEERRQVPVDEARGKAEEWGVQYVETS 158
            +F    E REQILRVK  +D +P+L+VGNK DLE+ R V  D+ +G A  +   ++ETS
Sbjct: 315 STFNDLQELREQILRVKDTDD-VPMLLVGNKCDLEDERVVGKDQGQGLARSFSCAFLETS 491

Query: 159 AKTRANVDKVFFDLMREIRAK 179
           AK R NV+++F DL+R+I  K
Sbjct: 492 AKARINVNEIFMDLVRQINKK 554

 Score = 36.6 bits (83), Expect(2) = 4e-42,   Method: Compositional matrix adjust.
 Identities = 15/25 (60%), Positives = 23/25 (92%)
 Frame = +2

Query: 15 HKVIMVGSGGVGKSALTLQFMYDEF 39
          +K++++GSGGVGKSALT+QF+  +F
Sbjct: 62 YKLVVLGSGGVGKSALTVQFVQGDF 136
>00858
          Length = 1658

 Score =  151 bits (381), Expect = 2e-37,   Method: Compositional matrix adjust.
 Identities = 80/152 (52%), Positives = 109/152 (71%), Gaps = 2/152 (1%)
 Frame = -2

Query: 27   KSALTLQFMYDEFVEDYEPTKADSYRKKVVLDGEEVQIDILDTAGQEDYAAIRDNYFRSG 86
            KSALT+Q   + FVE+Y+PT  DS RK+VV+DGE   +DILDTAGQE+ +A+RD   R+G
Sbjct: 1552 KSALTIQLXQNHFVEEYDPTXEDSXRKQVVIDGETCLLDILDTAGQEEXSAMRDQCMRTG 1373

Query: 87   EGFLLVFSITEHESFTATAEFREQILRVKSEEDKIPLLVVGNKSDLEERRQVPVDEARGK 146
            EGFL VF++   +SF    ++REQI RVK + D++P+++VGNK DL  R    V++ +GK
Sbjct: 1372 EGFLCVFAVXNLKSFEDINQYREQIKRVK-DADEVPMVLVGNKVDLPIRN---VEQRQGK 1205

Query: 147  --AEEWGVQYVETSAKTRANVDKVFFDLMREI 176
              AE + + YVETSAKTR  VD  F+ L+REI
Sbjct: 1204 HMAELYHIPYVETSAKTRQGVDDAFYTLVREI 1109
>19046
          Length = 445

 Score = 93.2 bits (230), Expect = 7e-20,   Method: Compositional matrix adjust.
 Identities = 49/109 (44%), Positives = 70/109 (64%), Gaps = 1/109 (0%)
 Frame = -2

Query: 72  QEDYAAIRDNYFRSGEGFLLVFSITEHESFTATAEFREQILRVKSEEDKIPLLVVGNKSD 131
           QE+++A+R+ Y R G+GFLLVFS+T+  SF   A F  QILRVK + D  P+++  NK D
Sbjct: 444 QEEFSAMREQYMRKGDGFLLVFSVTDFRSFENMANFHTQILRVK-DRDSYPMILCANKVD 268

Query: 132 LEERRQVPVDEARGKAEEWGVQYVETSAK-TRANVDKVFFDLMREIRAK 179
           L  +R+V  ++ R  A    + Y+ETSAK    NVD  F  ++R IRA+
Sbjct: 267 LVHQRKVSEEQVRDLATRLRIPYIETSAKDPPLNVDLAFHQVVRVIRAQ 121
>24619
          Length = 509

 Score = 92.4 bits (228), Expect = 1e-19,   Method: Compositional matrix adjust.
 Identities = 47/109 (43%), Positives = 70/109 (64%), Gaps = 1/109 (0%)
 Frame = -2

Query: 72  QEDYAAIRDNYFRSGEGFLLVFSITEHESFTATAEFREQILRVKSEEDKIPLLVVGNKSD 131
           QE+++A+R+ Y R G+GFLLVFS+ +++SF     F  QILRVK + D  P+++  NK D
Sbjct: 508 QEEFSAMREQYMRKGDGFLLVFSVIDYQSFENMVNFHTQILRVK-DRDTYPMILCANKVD 332

Query: 132 LEERRQVPVDEARGKAEEWGVQYVETSAK-TRANVDKVFFDLMREIRAK 179
           L  +R+V  ++ R  A    + Y+ETSAK    NVD  F  ++R IRA+
Sbjct: 331 LVHQRKVSEEQVRDLATRLRIPYIETSAKDPPLNVDLAFHQVVRVIRAQ 185
>26536
          Length = 829

 Score = 91.7 bits (226), Expect = 2e-19,   Method: Compositional matrix adjust.
 Identities = 52/116 (44%), Positives = 77/116 (66%), Gaps = 1/116 (0%)
 Frame = +2

Query: 62  VQIDILDTAGQEDYAAIRDNYFRSGEGFLLVFSITEHESFT-ATAEFREQILRVKSEEDK 120
           V    LDTAGQE+Y+++R++Y RSG+GF++V+S+T+  SF  A A FR  + R + +E  
Sbjct: 128 VSWTFLDTAGQEEYSSMREHYTRSGDGFIVVYSVTDVTSFQEAEAVFR-WLTRFQ-DETS 301

Query: 121 IPLLVVGNKSDLEERRQVPVDEARGKAEEWGVQYVETSAKTRANVDKVFFDLMREI 176
           I  ++ GNK+DL   R+V  +E R  A+  G+ Y ETSAKT  NV +V+  L+R I
Sbjct: 302 IHAVLCGNKTDLTSDRKVTPEEGRKMADRLGMLYFETSAKTGDNVSQVYHGLLRSI 469

 Score = 58.5 bits (140), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 24/46 (52%), Positives = 37/46 (80%)
 Frame = +2

Query: 15  HKVIMVGSGGVGKSALTLQFMYDEFVEDYEPTKADSYRKKVVLDGE 60
           +K++M+GSGGVGKS+LT++F  D F++ Y+PT  DSYRK + + G+
Sbjct: 488 YKIVMLGSGGVGKSSLTIRFTQDTFLDVYDPTIEDSYRKMIQVSGQ 625
>14456
          Length = 1867

 Score = 89.7 bits (221), Expect = 8e-19,   Method: Compositional matrix adjust.
 Identities = 56/159 (35%), Positives = 88/159 (55%), Gaps = 4/159 (2%)
 Frame = -1

Query: 23   GGVGKSALTLQFMYDEF-VEDYEPTKADSYRKKVVLDGEEVQIDILDTAGQEDYAAIRDN 81
            GGVGKS+L  +F+ ++F  + +     +   K VV+D E   + I DTAGQE + ++R  
Sbjct: 1114 GGVGKSSLMNRFVSNKFDAQSFHTIGVEFLNKDVVVDDETYTMQIWDTAGQERFKSLRTP 935

Query: 82   YFRSGEGFLLVFSITEHESFTATAEFREQILRVKSEEDKI--PLLVVGNKSDLEERRQVP 139
            ++R  +  LL FS+   +SF   + +R++ L     +D +  P +V+GNK D+E  RQV 
Sbjct: 934  FYRGADCCLLTFSVDSMQSFRNLSMWRKEFLYYADIQDGVTFPFVVLGNKIDVEG-RQVT 758

Query: 140  VDEARGKAE-EWGVQYVETSAKTRANVDKVFFDLMREIR 177
             +EAR          Y ETSAK   NV+K F   ++ +R
Sbjct: 757  NEEARSWCTANSNAPYFETSAKDATNVEKAFLAAVQRLR 641
>08428
          Length = 1109

 Score = 89.0 bits (219), Expect = 1e-18,   Method: Compositional matrix adjust.
 Identities = 53/162 (32%), Positives = 88/162 (54%), Gaps = 1/162 (0%)
 Frame = -3

Query: 16   KVIMVGSGGVGKSALTLQFMYDEFVEDYEPTKADSY-RKKVVLDGEEVQIDILDTAGQED 74
            KV ++G  GVGKS++ L+F+   +    E T   S+  K +V+DG   +  I DTAGQE 
Sbjct: 1065 KVCLLGDSGVGKSSIVLRFVTGSYRPSQESTIGASFMSKSLVVDGAGYRFQIWDTAGQEK 886

Query: 75   YAAIRDNYFRSGEGFLLVFSITEHESFTATAEFREQILRVKSEEDKIPLLVVGNKSDLEE 134
            + A+   Y+R     ++V+ +T   +F +   + +++         I L + GNK DLEE
Sbjct: 885  FRALAPMYYRGAAAAVIVYDVTRPRTFKSVKSWIQELRSFGP--PNIVLAIAGNKCDLEE 712

Query: 135  RRQVPVDEARGKAEEWGVQYVETSAKTRANVDKVFFDLMREI 176
             R+V   +A+  A      + ETSA T  NV+++F +L R++
Sbjct: 711  LREVVEKDAQEYASSISAIFGETSAMTAVNVEEMFTELARQL 586
>11257
          Length = 1102

 Score = 82.4 bits (202), Expect = 1e-16,   Method: Compositional matrix adjust.
 Identities = 49/158 (31%), Positives = 82/158 (51%), Gaps = 5/158 (3%)
 Frame = -2

Query: 52   RKKVVLDGEEVQIDILDTAGQEDYAAIRDNYFRSGEGFLLVFSITEHESFTATAEFREQI 111
             K VV+DGE   + I DTAGQE Y ++R  ++R  +  LL FS+   +S  + +++ ++ 
Sbjct: 1056 HKDVVVDGETFTMQIWDTAGQERYKSLRTPFYRGTDCCLLTFSVDNLKSLQSLSDWYDEF 877

Query: 112  LRVKSEED--KIPLLVVGNKSDLEERRQVPVDEARGKAEEWG-VQYVETSAKTRANVDKV 168
            +     +D    P +++GNK+D+EE R+V  ++A       G + Y ETSAK   NV + 
Sbjct: 876  VNYADIQDSASFPFVIIGNKADIEE-REVSSEDAYNWCRTHGNLPYFETSAKDSLNVQQA 700

Query: 169  FFDLMREIRA--KKMSENKDKNGRXXXXXXXXFKERCC 204
            F  ++R +R   ++M E   +            K  CC
Sbjct: 699  FLAVVRRLREMDEQMDERPTRTDTVDLKRVAKVKSSCC 586
>11728
          Length = 635

 Score = 80.1 bits (196), Expect = 6e-16,   Method: Compositional matrix adjust.
 Identities = 49/161 (30%), Positives = 84/161 (52%), Gaps = 14/161 (8%)
 Frame = -1

Query: 16  KVIMVGSGGVGKSALTLQFMYDEFVEDYEPTKADSYRKKVVLDGEEVQIDILDTAGQEDY 75
           K ++VG G VGK+ L + +  + F  +Y PT  D+Y   V++D + + + + DTAGQEDY
Sbjct: 485 KCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDSKPINLGLWDTAGQEDY 306

Query: 76  AAIRDNYFRSGEGFLLVFSITEHESF-TATAEFREQILRVKSEEDKIPLLVVGNKSD--- 131
             +R   +   + FL+ FS+    SF    A++  +   V       P+++VG K D   
Sbjct: 305 DRLRPLSYPQTDVFLICFSLISPASFENVKAKWYPE---VSHHCPNTPIILVGTKLDLRE 135

Query: 132 -------LEERRQVPVDEARG--KAEEWGV-QYVETSAKTR 162
                  L+E++  P+   +G   A++ G  +Y+E SA T+
Sbjct: 134 DKETIEKLKEKKLAPITYPQGLAMAKDIGAGKYLECSALTQ 12
>34468
          Length = 1502

 Score = 79.7 bits (195), Expect = 7e-16,   Method: Compositional matrix adjust.
 Identities = 53/172 (30%), Positives = 95/172 (55%), Gaps = 5/172 (2%)
 Frame = +1

Query: 14  LHKVIMVGSGGVGKSALTLQFMYDEFVEDYEPTKADSYRKKVV-LDGEEVQIDILDTAGQ 72
           + K+I++G   VGK+ LT +F   +F +  E T    +R+K + +D E +++ + DTAGQ
Sbjct: 493 IFKIIVIGDSNVGKTCLTYRFCLGKFPDKTEATIGVDFREKSIQVDSEHLKLQLWDTAGQ 672

Query: 73  EDY-AAIRDNYFRSGEGFLLVFSITEHESFTATAEFREQILRVKSEEDKIPLLVVGNKSD 131
           E +  ++  +Y+R+    + V+ +T+  SF     + E+  R  +    IP ++VGNK D
Sbjct: 673 ERFRKSMVQHYYRNVHAVVFVYDMTKMSSFENMPAWIEECDR-HNLTKYIPRILVGNKCD 849

Query: 132 LEERRQVPVDEARGKAEEWGVQYVETSAKT--RAN-VDKVFFDLMREIRAKK 180
           + ER  V  + A+  A+   +   ETSAK   +AN VD +F  +  +++  K
Sbjct: 850 VVERIAVNTNLAQKFADAHNMPLFETSAKDDEKANHVDAIFMTVAHKLKXSK 1005
>17511
          Length = 483

 Score = 78.2 bits (191), Expect = 2e-15,   Method: Compositional matrix adjust.
 Identities = 45/123 (36%), Positives = 72/123 (58%), Gaps = 3/123 (2%)
 Frame = -3

Query: 13  VLHKVIMVGSGGVGKSALTLQFMYDEFVEDYEPT-KADSYRKKVVLDGEEVQIDILDTAG 71
           VL KVI++G  GVGK++L  Q++  +F   Y+ T  AD   K+V++D   V + I DTAG
Sbjct: 370 VLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQIWDTAG 191

Query: 72  QEDYAAIRDNYFRSGEGFLLVFSITEHESFTATAEFREQILRVKSEED--KIPLLVVGNK 129
           QE + ++   ++R  +  +LVF +T   +F +   +R++ L   S  D    P +V+GNK
Sbjct: 190 QERFQSLGVAFYRGADCCVLVFDVTMPNTFRSLDSWRDEFLIQASPRDPENFPFVVIGNK 11

Query: 130 SDL 132
            DL
Sbjct: 10  IDL 2
>30760
          Length = 596

 Score = 77.8 bits (190), Expect = 3e-15,   Method: Compositional matrix adjust.
 Identities = 50/162 (30%), Positives = 85/162 (52%), Gaps = 5/162 (3%)
 Frame = -1

Query: 16  KVIMVGSGGVGKSALTLQFMYD--EFVEDYEPTKADSYRKKVVL---DGEEVQIDILDTA 70
           K I+ G  GVGKS++   F  D   F ++Y  T       K+V      ++V++ + D+A
Sbjct: 524 KCIVTGDSGVGKSSICQVFHSDSAHFPKNYSMTTGVEVLVKLVNIPDSRDQVELYLFDSA 345

Query: 71  GQEDYAAIRDNYFRSGEGFLLVFSITEHESFTATAEFREQILRVKSEEDKIPLLVVGNKS 130
           G+E ++     ++      ++V+ +T+  SF+    + E++ R       IP ++V NK+
Sbjct: 344 GKEIFSENVTKFWDQPSVVMVVYDVTDETSFSGCVRWLERV-RAAKPNTVIPGVLVANKT 168

Query: 131 DLEERRQVPVDEARGKAEEWGVQYVETSAKTRANVDKVFFDL 172
           DL+ERR+V   E +  A+  G++Y E SAK   N D  FF L
Sbjct: 167 DLDERRRVSRKEGKDLAQSHGLEYFECSAKEMQNTDTPFFCL 42
>36482
          Length = 686

 Score = 77.4 bits (189), Expect = 4e-15,   Method: Compositional matrix adjust.
 Identities = 48/154 (31%), Positives = 83/154 (53%), Gaps = 3/154 (1%)
 Frame = +2

Query: 30  LTLQFMYDEFVEDYEPTKADSYRKKVVLDGEEVQIDILDTAGQEDYAAIRDNYFRSGEGF 89
           LT++F+   F+ +Y PT    Y+   V++ ++V+++ILDTAGQ  Y   ++ Y    + F
Sbjct: 2   LTVRFLTRRFIGEYCPTLESVYKYHTVIEDDDVRLEILDTAGQGTY-PWKEGYALWADCF 178

Query: 90  LLVFSITEHESFTATAEFREQILRVKSEEDKIPLLVVGNKSDLEERRQVPVDEARGKAEE 149
           + V+SI + +S+    + + Q+  V+ +   +  ++  NK+DL   RQV   E    AEE
Sbjct: 179 VFVYSINDRQSYEELVQVKRQVESVR-KSTSLTAVLAANKTDLLHDRQVTQKEGEDLAEE 355

Query: 150 WGVQYVETSAKTRANVDKV---FFDLMREIRAKK 180
            G +  E SA   + ++ +   F DL RE R  K
Sbjct: 356 IGCRLYEVSASEGSQMEAITSMFHDLYREFRKHK 457
>19006
          Length = 568

 Score = 77.4 bits (189), Expect = 4e-15,   Method: Compositional matrix adjust.
 Identities = 40/117 (34%), Positives = 66/117 (56%)
 Frame = -2

Query: 16  KVIMVGSGGVGKSALTLQFMYDEFVEDYEPTKADSYRKKVVLDGEEVQIDILDTAGQEDY 75
           K+++VG G  GK+ L + F  D+F E Y PT  ++Y   + +D ++V++ + DTAGQEDY
Sbjct: 432 KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDSKQVELALWDTAGQEDY 253

Query: 76  AAIRDNYFRSGEGFLLVFSITEHESFTATAEFREQILRVKSEEDKIPLLVVGNKSDL 132
             +R   +   +  L+ FSI   +S     E  +    V+     +P+++VGNK DL
Sbjct: 252 DRLRPLSYPDTDVILMCFSIDSPDSLENIPE--KWTPEVRHFCPNVPIILVGNKKDL 88
>06994
          Length = 429

 Score = 58.5 bits (140), Expect(2) = 6e-15,   Method: Compositional matrix adjust.
 Identities = 31/91 (34%), Positives = 45/91 (49%), Gaps = 32/91 (35%)
 Frame = +1

Query: 43  YEPTKADSYRKKVVLDGEEVQIDILDTAGQ------------------------------ 72
           Y+PT  DSYRK+V +DG++  ++ILDTAG                               
Sbjct: 142 YDPTIEDSYRKQVEVDGQQCMLEILDTAGTVHASHSNACVHGSLHAFVGTVTPLGRDALL 321

Query: 73  --EDYAAIRDNYFRSGEGFLLVFSITEHESF 101
             E + A+RD Y ++G+GFLL +SIT   +F
Sbjct: 322 NTEQFTAMRDLYMKNGQGFLLAYSITAQSTF 414

 Score = 38.5 bits (88), Expect(2) = 6e-15,   Method: Compositional matrix adjust.
 Identities = 17/27 (62%), Positives = 24/27 (88%)
 Frame = +3

Query: 15 HKVIMVGSGGVGKSALTLQFMYDEFVE 41
          +K++++GSGGVGKSALT+QF+   FVE
Sbjct: 57 YKLVVLGSGGVGKSALTVQFVQGIFVE 137
>33374
          Length = 489

 Score = 76.3 bits (186), Expect = 9e-15,   Method: Compositional matrix adjust.
 Identities = 41/116 (35%), Positives = 68/116 (58%)
 Frame = +1

Query: 53  KKVVLDGEEVQIDILDTAGQEDYAAIRDNYFRSGEGFLLVFSITEHESFTATAEFREQIL 112
           + V LD   V+ +I DTAGQE Y ++   Y+R  +  ++V+ IT  ++F     + +++ 
Sbjct: 148 QTVCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNQDTFGRAKTWVKELQ 327

Query: 113 RVKSEEDKIPLLVVGNKSDLEERRQVPVDEARGKAEEWGVQYVETSAKTRANVDKV 168
           R  S    I + + GNK+DL  +R V  +EA+  AEE  + ++ETSAKT  NV+ +
Sbjct: 328 RQASP--NIVIALAGNKADLANKRMVEFEEAQAYAEENSLLFMETSAKTAMNVNDI 489
>19656
          Length = 428

 Score = 73.6 bits (179), Expect = 5e-14,   Method: Compositional matrix adjust.
 Identities = 34/86 (39%), Positives = 50/86 (58%)
 Frame = +3

Query: 16  KVIMVGSGGVGKSALTLQFMYDEFVEDYEPTKADSYRKKVVLDGEEVQIDILDTAGQEDY 75
           K ++VG G VGK+ L + +  + F  +Y PT  D+Y   V++DG  V + + DTAGQEDY
Sbjct: 117 KCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGRPVNLGLWDTAGQEDY 296

Query: 76  AAIRDNYFRSGEGFLLVFSITEHESF 101
             +R   +   + FLL FS+    SF
Sbjct: 297 DRLRPLSYPQTDVFLLCFSVASPASF 374
>07465
          Length = 1103

 Score = 72.0 bits (175), Expect = 2e-13,   Method: Compositional matrix adjust.
 Identities = 45/143 (31%), Positives = 82/143 (57%), Gaps = 1/143 (0%)
 Frame = +3

Query: 28  SALTLQFMYDEFVEDYEPT-KADSYRKKVVLDGEEVQIDILDTAGQEDYAAIRDNYFRSG 86
           S++  ++    F +DY+ T   D   +++ + GE+V++ + DTAGQE++ AI   Y+R  
Sbjct: 240 SSMIQRYCKGIFTKDYKKTIGVDFLERQIEVGGEDVRLMLWDTAGQEEFDAITKAYYRGA 419

Query: 87  EGFLLVFSITEHESFTATAEFREQILRVKSEEDKIPLLVVGNKSDLEERRQVPVDEARGK 146
           +  +L FS  + +SF A   ++    +V+ E  +I +++V NK DL +   V  +EA   
Sbjct: 420 QACVLAFSTVDRDSFEALETWKR---KVEDEVGEIGMVIVQNKIDLIDDAVVRPEEAENL 590

Query: 147 AEEWGVQYVETSAKTRANVDKVF 169
           A++  +++  TS K   NVD+VF
Sbjct: 591 AKKLRLRFYRTSVKENMNVDEVF 659
>18509
          Length = 625

 Score = 58.9 bits (141), Expect(2) = 3e-12,   Method: Compositional matrix adjust.
 Identities = 38/76 (50%), Positives = 51/76 (67%), Gaps = 2/76 (2%)
 Frame = -3

Query: 113 RVKSEEDKIPLLVVGNKSDLEERRQVPVDEARGK--AEEWGVQYVETSAKTRANVDKVFF 170
           RVK + D++P+++VGNK DL  R    V++ +GK  AE + + YVETSAKTR  VD  F+
Sbjct: 548 RVK-DADEVPMVLVGNKVDLPIRN---VEQRQGKHMAELYHIPYVETSAKTRQGVDDAFY 381

Query: 171 DLMREIRAKKMSENKD 186
            L+REIR  K  E KD
Sbjct: 380 TLVREIR--KYKERKD 339

 Score = 28.5 bits (62), Expect(2) = 3e-12,   Method: Compositional matrix adjust.
 Identities = 12/25 (48%), Positives = 17/25 (68%)
 Frame = -1

Query: 87  EGFLLVFSITEHESFTATAEFREQI 111
           EGFL VF++   +SF    ++REQI
Sbjct: 625 EGFLCVFAVNNLKSFEDINQYREQI 551
>13750
          Length = 503

 Score = 67.4 bits (163), Expect = 4e-12,   Method: Compositional matrix adjust.
 Identities = 40/116 (34%), Positives = 65/116 (56%), Gaps = 1/116 (0%)
 Frame = -2

Query: 58  DGEEVQIDILDTAGQEDYAAIRDNYFRSGEGFLLVFSITEHESF-TATAEFREQILRVKS 116
           D   V+  + DT G E Y ++  ++FR  +  LLV+ +T   SF TAT  +R+ +++   
Sbjct: 403 DPLNVRYTLWDTGGAETYRSLWVSHFRGAQVALLVYDVTCEWSFLTATTVWRKALMKNIP 224

Query: 117 EEDKIPLLVVGNKSDLEERRQVPVDEARGKAEEWGVQYVETSAKTRANVDKVFFDL 172
           E   I    VG+K+DLEE R +  +  +  A + G  + ETS+ T  NVD VF+++
Sbjct: 223 EAQVI---FVGSKTDLEENRVISTERGQAFATQCGYTFFETSSVTGKNVDAVFWEI 65
>01972
          Length = 2359

 Score = 63.9 bits (154), Expect = 4e-11,   Method: Compositional matrix adjust.
 Identities = 33/120 (27%), Positives = 67/120 (55%), Gaps = 4/120 (3%)
 Frame = +3

Query: 61  EVQIDILDTAGQEDYAAIRDNYFRSGEGFLLVFSITEHESFTATAEFREQILRVKSEEDK 120
           +++ ++ DTAGQE +  +RD Y+  G+  +++F +T   ++     +   ++RV    + 
Sbjct: 444 KLKFNVWDTAGQEKFGGLRDGYYIQGQCAVIMFDVTSRVTYKNVPNWHRDLVRV---CEN 614

Query: 121 IPLLVVGNKSDLEERRQVPVDEARGKA----EEWGVQYVETSAKTRANVDKVFFDLMREI 176
           IP+++ GNK D+++R+       + KA     +  +QY + SAK+  N +K F  L R++
Sbjct: 615 IPIVLCGNKVDIKDRK------VKAKAIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKL 776
>01398
          Length = 1421

 Score = 63.9 bits (154), Expect = 4e-11,   Method: Compositional matrix adjust.
 Identities = 37/104 (35%), Positives = 62/104 (59%)
 Frame = -2

Query: 72   QEDYAAIRDNYFRSGEGFLLVFSITEHESFTATAEFREQILRVKSEEDKIPLLVVGNKSD 131
            QE + +I  +Y+R+  G ++V+ IT+  +F    ++ E+  R   E  K   LV+G+KSD
Sbjct: 1420 QERFRSITRSYYRNSVGVIIVYDITKRSTFENLKQWYEE-ARNHIEPHKAIFLVLGHKSD 1244

Query: 132  LEERRQVPVDEARGKAEEWGVQYVETSAKTRANVDKVFFDLMRE 175
             E+ RQV   E R  AE  G+++ ETSAK+  N++ VF  + ++
Sbjct: 1243 REDARQVTAREGRRFAEMHGLKFFETSAKSGHNIEDVFAQIAKD 1112
>26083
          Length = 432

 Score = 63.5 bits (153), Expect = 5e-11,   Method: Compositional matrix adjust.
 Identities = 39/130 (30%), Positives = 71/130 (54%), Gaps = 1/130 (0%)
 Frame = +1

Query: 1   MAANKGKSQGSLVLHKVIMVGSGGVGKSALTLQFMYDEFVEDYEPTKA-DSYRKKVVLDG 59
           +  + G+    L   K++ +G   VGK++L  +FMYD F   Y+ T   D   K + L+ 
Sbjct: 37  IMTSSGEFGNPLRKFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLED 216

Query: 60  EEVQIDILDTAGQEDYAAIRDNYFRSGEGFLLVFSITEHESFTATAEFREQILRVKSEED 119
             +++ + DTAGQE + ++  +Y R     ++V+ IT   SF  T+++ + + R +   D
Sbjct: 217 RTIRLQLWDTAGQERFRSLIPSYIRDSSVAVVVYDITNANSFHQTSKWIDDV-RTERGSD 393

Query: 120 KIPLLVVGNK 129
            I +++VGNK
Sbjct: 394 VI-IMLVGNK 420
>33380
          Length = 282

 Score = 62.0 bits (149), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 31/75 (41%), Positives = 44/75 (58%)
 Frame = +3

Query: 62  VQIDILDTAGQEDYAAIRDNYFRSGEGFLLVFSITEHESFTATAEFREQILRVKSEEDKI 121
           V++ I DTAGQE Y  I   Y+R   GF+L++ +T  ESF A  ++  QI       D  
Sbjct: 60  VKLQIWDTAGQERYRTITTAYYRGAMGFILMYDVTNEESFNAVQDWCTQIK--TYSWDNA 233

Query: 122 PLLVVGNKSDLEERR 136
            +++VGNK DLE+ R
Sbjct: 234 QVVLVGNKCDLEDER 278
>33794
          Length = 779

 Score = 62.0 bits (149), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 36/120 (30%), Positives = 61/120 (50%)
 Frame = -1

Query: 55  VVLDGEEVQIDILDTAGQEDYAAIRDNYFRSGEGFLLVFSITEHESFTATAEFREQILRV 114
           ++L+G+ V++ I DT+GQ  +  I  +Y R  +G +LV+ IT   SF     + ++   V
Sbjct: 671 ILLEGKRVKLQIWDTSGQGRFCTIIRSYSRGAQGIILVYDITNKWSFDGIDRWLKE---V 501

Query: 115 KSEEDKIPLLVVGNKSDLEERRQVPVDEARGKAEEWGVQYVETSAKTRANVDKVFFDLMR 174
           +     IP ++VGN+  L  +RQV   +A   A    +   E S     N+ + F +L R
Sbjct: 500 EEHAPGIPKVLVGNRLHLAYKRQVAAKQAETYASRNNMSCFEISPLCDFNIRESFCELAR 321
>34359
          Length = 1042

 Score = 55.1 bits (131), Expect(2) = 3e-10,   Method: Compositional matrix adjust.
 Identities = 21/75 (28%), Positives = 45/75 (60%)
 Frame = +3

Query: 62  VQIDILDTAGQEDYAAIRDNYFRSGEGFLLVFSITEHESFTATAEFREQILRVKSEEDKI 121
           ++ ++ DTAGQE +  +RD Y+  G   +++F +T   ++     +   ++RV    + I
Sbjct: 195 LRFNVWDTAGQEKFGGLRDGYYIQGTCAIIMFDVTSRVTYKNVPNWHRDLVRV---CENI 365

Query: 122 PLLVVGNKSDLEERR 136
           P+++ GNK D+++R+
Sbjct: 366 PIVLCGNKVDIKDRK 410

 Score = 25.8 bits (55), Expect(2) = 3e-10,   Method: Compositional matrix adjust.
 Identities = 11/30 (36%), Positives = 19/30 (63%)
 Frame = +2

Query: 147 AEEWGVQYVETSAKTRANVDKVFFDLMREI 176
           ++E  +QY + SAK+  N +K F  L R++
Sbjct: 434 SQEKNLQYYDISAKSNYNFEKPFLWLARKL 523
>05468
          Length = 1558

 Score = 57.8 bits (138), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 40/161 (24%), Positives = 86/161 (53%), Gaps = 8/161 (4%)
 Frame = -3

Query: 14   LHKVIMVGSGGVGKSALTLQFMYDEFVEDYEPTKADSYRKKVV-LDGEE-VQIDILDTAG 71
            L+K++++G  G GK+++  ++++  F + Y  T    +  KV+  D +  +++ + D AG
Sbjct: 1541 LYKILVIGELGTGKTSIIKRYVHQFFSQHYRATIGVDFALKVLNWDADTLIRLQLWDIAG 1362

Query: 72   QEDYAAIRDNYFRSGEGFLLVFSITEHESFTATAEFREQI-LRVK-SEEDKIPLLVVGNK 129
            QE +  +   Y++   G  +VF +T   +F A  +++  +  +V+ ++   +P +++ NK
Sbjct: 1361 QERFGNMTRVYYKEAVGAFVVFDVTRASTFDAVTKWKNDLDSKVQLADGSPVPCVLLANK 1182

Query: 130  SDLEERRQV----PVDEARGKAEEWGVQYVETSAKTRANVD 166
             D  +   V     +DE    +E+  + + ETSAK   N+D
Sbjct: 1181 CDQAKEGLVNNTSQMDEF--CSEKGFIGWYETSAKENINID 1065
>32723
          Length = 384

 Score = 57.8 bits (138), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 30/108 (27%), Positives = 61/108 (56%)
 Frame = +2

Query: 72  QEDYAAIRDNYFRSGEGFLLVFSITEHESFTATAEFREQILRVKSEEDKIPLLVVGNKSD 131
           QE + +I  +Y+RS    +LV+ +   +S+ +  ++  +I        K+   +VGNK D
Sbjct: 2   QERFRSITQSYYRSANALILVYDVCSQQSYESLPQWIHEIELYAG--TKVLAFLVGNKID 175

Query: 132 LEERRQVPVDEARGKAEEWGVQYVETSAKTRANVDKVFFDLMREIRAK 179
             ++R++P    +  AE + ++++ETSAK   NV+K+F  +  ++ A+
Sbjct: 176 QTDKREIPTHIGKEFAERYEMRFLETSAKEADNVEKLFSTIAYQLTAQ 319
>01095
          Length = 1745

 Score = 53.5 bits (127), Expect = 6e-08,   Method: Compositional matrix adjust.
 Identities = 33/99 (33%), Positives = 56/99 (56%)
 Frame = -1

Query: 91   LVFSITEHESFTATAEFREQILRVKSEEDKIPLLVVGNKSDLEERRQVPVDEARGKAEEW 150
            +V+ IT  ++F     + +++ R  S    I + + GNK+DL  +R V  +EA+  AEE 
Sbjct: 1745 VVYDITNQDTFGRAKTWVKELQRQASP--NIVIALAGNKADLANKRMVEFEEAQAYAEEN 1572

Query: 151  GVQYVETSAKTRANVDKVFFDLMREIRAKKMSENKDKNG 189
             + ++ETSAKT  NV+ +F  +     AKK+ +N+   G
Sbjct: 1571 SLLFMETSAKTAMNVNDIFLAI-----AKKLPKNEGGGG 1470
>13901
          Length = 962

 Score = 52.0 bits (123), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 25/91 (27%), Positives = 51/91 (56%), Gaps = 2/91 (2%)
 Frame = -3

Query: 13  VLHKVIMVGSGGVGKSALTLQFMYDEFVEDYEPTKADSYRKKVVL--DGEEVQIDILDTA 70
           VL KVI++G   VGK++   +++ D F  DY+ T    +  KV+   D   +++ + D A
Sbjct: 291 VLFKVIIIGDPTVGKTSFVQRYVNDSFRRDYKMTIGVDFALKVIRWSDKCNIKLQLWDIA 112

Query: 71  GQEDYAAIRDNYFRSGEGFLLVFSITEHESF 101
           GQE + ++   Y++     +++F +T+  ++
Sbjct: 111 GQERFTSMTRVYYKDAHACIVMFDLTQKNTY 19
>17872
          Length = 700

 Score = 50.8 bits (120), Expect = 4e-07,   Method: Compositional matrix adjust.
 Identities = 42/142 (29%), Positives = 65/142 (45%), Gaps = 27/142 (19%)
 Frame = -1

Query: 72  QEDYAAIRDNYFRSGEGFLLVFSITEHESFTATAEFREQILRVKSEEDKIPLLVVGNKSD 131
           Q+D+ ++R   +     FLL FS+    SF    E  + +  ++      PL+VVG +SD
Sbjct: 700 QDDFDSLRPLCYPETNVFLLCFSVVSPTSFHNVME--KWVPELRYHCPGAPLVVVGTQSD 527

Query: 132 LEERRQV----------PV--DEARGKAEEWGVQYVETSAKTRANVDKVF---------- 169
           L    +V          PV  +EA   A++ G QYVE SA T+ N+ +VF          
Sbjct: 526 LRNDVKVLIELAKYKEKPVSEEEAVKMADQLGAQYVECSALTQKNLKEVFDTGILASLNW 347

Query: 170 -----FDLMREIRAKKMSENKD 186
                F   + +R  K S++KD
Sbjct: 346 TDREVFTRSKSLRKSKRSKSKD 281
>35581
          Length = 364

 Score = 48.9 bits (115), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 26/86 (30%), Positives = 45/86 (52%), Gaps = 2/86 (2%)
 Frame = +2

Query: 16  KVIMVGSGGVGKSALTLQFMYDEFVED--YEPTKADSYRKKVVLDGEEVQIDILDTAGQE 73
           K +++G  GVGK+ L  +   D+F++      T A       +  G    +D+ DTAGQE
Sbjct: 50  KCVLLGDAGVGKTCLLNRLATDKFLDSPLTSLTTASLLTTVTLTSGVMASVDLWDTAGQE 229

Query: 74  DYAAIRDNYFRSGEGFLLVFSITEHE 99
            Y ++  +Y+R  +  L+V+   EH+
Sbjct: 230 RYRSLTSSYYRDTKAVLIVYD-AEHK 304
>09204
          Length = 1051

 Score = 48.5 bits (114), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 31/99 (31%), Positives = 50/99 (50%), Gaps = 4/99 (4%)
 Frame = -3

Query: 75   YAAIRDNYFRSGEGFLLVFSITEHESFTATAEFREQILRVKSEEDKIPLLVVGNKSDL-- 132
            Y A+   Y+R  +  +L F +T+  SF      R  I  ++  E++  L + G K DL  
Sbjct: 1046 YEAMSRIYYRGAKAAILCFDLTDKSSFD---RIRFWIGELRQHEEECKLYICGTKFDLVH 876

Query: 133  --EERRQVPVDEARGKAEEWGVQYVETSAKTRANVDKVF 169
               ERR VP   A+  A++   +  ETS+ T  N++K+F
Sbjct: 875  DDPERRAVPRSVAKALADDCMAEIYETSSMTGDNIEKLF 759
>31291
          Length = 446

 Score = 47.8 bits (112), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 34/125 (27%), Positives = 60/125 (48%), Gaps = 14/125 (11%)
 Frame = -1

Query: 64  IDILDTAGQEDYAAIRDNYFRSGEGFLLVFSITEHESF-TATAEFREQILRVKSEEDKIP 122
           + + DTAGQEDY  +R   + + + F+L FS+    S      ++  +I   +  +  +P
Sbjct: 446 LQLWDTAGQEDYDRLRPLAYPNTDVFMLXFSLMSEASMKNVKVKWYPEI---RHHDPHVP 276

Query: 123 LLVVGNKSDLEE----------RRQVPVDEARGKAEEWGVQ---YVETSAKTRANVDKVF 169
           +++VG K DL +           RQ PV   +G      ++   Y E S+KT+ N+   F
Sbjct: 275 IVLVGTKLDLRQDKEAVRKLRSSRQDPVSSNQGNDLAKAIKAKRYFECSSKTQENLKTAF 96

Query: 170 FDLMR 174
            + +R
Sbjct: 95  EETVR 81
>34597
          Length = 773

 Score = 41.2 bits (95), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 17/53 (32%), Positives = 33/53 (62%)
 Frame = -2

Query: 124 LVVGNKSDLEERRQVPVDEARGKAEEWGVQYVETSAKTRANVDKVFFDLMREI 176
           +++GNK D+ ++R V  +     A E  ++++ETSAK+  N+++ F +L   I
Sbjct: 643 MILGNKCDMTDKRVVSKERGEAIAREHSIRFMETSAKSNINIERAFCELAEAI 485
>00552
          Length = 455

 Score = 37.4 bits (85), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 19/48 (39%), Positives = 31/48 (64%), Gaps = 1/48 (2%)
 Frame = -1

Query: 14  LHKVIMVGSGGVGKSALTLQFMYDEF-VEDYEPTKADSYRKKVVLDGE 60
           L KV+++G GGVGKS+L  +F+ ++F  + +     +   K VV+DGE
Sbjct: 446 LLKVVLLGDGGVGKSSLMNRFVSNKFDAQSFHTIGVEFLTKDVVVDGE 303

 Score = 36.2 bits (82), Expect = 0.010,   Method: Compositional matrix adjust.
 Identities = 15/47 (31%), Positives = 29/47 (61%)
 Frame = -3

Query: 66  ILDTAGQEDYAAIRDNYFRSGEGFLLVFSITEHESFTATAEFREQIL 112
           I DTAGQE Y ++R  ++R  +  LL FS+   +S  + +++ ++ +
Sbjct: 147 IWDTAGQERYKSLRTPFYRGTDCCLLTFSVDNLKSLQSLSDWYDEFV 7
>09827
          Length = 1201

 Score = 37.4 bits (85), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 29/121 (23%), Positives = 55/121 (45%), Gaps = 2/121 (1%)
 Frame = -3

Query: 16   KVIMVGSGGVGKSALTLQFMYDEFVEDYEPTKADSYRKKVVLDGEEVQIDILDTAGQEDY 75
            +++MVG    GK+ +  +    E V    PT   +      ++ + +   + D  GQ+  
Sbjct: 1109 RILMVGLDAAGKTTILYKLKLGEIVTTI-PTIGFNVE---TVEYKNISFTVWDVGGQDKI 942

Query: 76   AAIRDNYFRSGEGFLLVFSITEHESFTATAEFREQILRVKSEED--KIPLLVVGNKSDLE 133
              +  +YF++ +G + V    + E      E RE++ R+ +E++     LLV  NK DL 
Sbjct: 941  RPLWRHYFQNTQGLIFVVDSNDKER---VQEAREELTRMLNEDELRDAVLLVFANKQDLP 771

Query: 134  E 134
             
Sbjct: 770  H 768
>08153
          Length = 1703

 Score = 37.0 bits (84), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 28/119 (23%), Positives = 55/119 (46%), Gaps = 2/119 (1%)
 Frame = +1

Query: 16  KVIMVGSGGVGKSALTLQFMYDEFVEDYEPTKADSYRKKVVLDGEEVQIDILDTAGQEDY 75
           +++MVG    GK+ +  +    E V    PT   +      ++ + +   + D  GQ+  
Sbjct: 88  RILMVGLDAAGKTTILYKLKLGEIVTTI-PTIGFNVE---TVEYKNISFTVWDVGGQDKI 255

Query: 76  AAIRDNYFRSGEGFLLVFSITEHESFTATAEFREQILRVKSEED--KIPLLVVGNKSDL 132
             +  +YF++ +G + V    + E      E +E++ R+ +E+D     +LV  NK DL
Sbjct: 256 RPLWRHYFQNTQGLIFVVDSNDRERIN---EAKEELARMLNEDDLRDAIILVFANKQDL 423
>10708
          Length = 2775

 Score = 34.7 bits (78), Expect = 0.027,   Method: Compositional matrix adjust.
 Identities = 16/47 (34%), Positives = 26/47 (55%)
 Frame = -2

Query: 60   EEVQIDILDTAGQEDYAAIRDNYFRSGEGFLLVFSITEHESFTATAE 106
            ++V++ + DTAGQEDY  +R   +   +  L+ FSI   +S     E
Sbjct: 2729 QQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPE 2589

 Score = 33.9 bits (76), Expect = 0.042,   Method: Compositional matrix adjust.
 Identities = 30/101 (29%), Positives = 47/101 (46%), Gaps = 22/101 (21%)
 Frame = -3

Query: 91   LVFSITEHESF-----TATAEFREQILRVKSEE----DKIPLLVVGNKSDLE-------- 133
            L  ++T+  S      TA   +R  + +   E       +P+++VGNK DL         
Sbjct: 2668 LCLTLTQMSSLCASPLTALTAWRTSLKKWTPEVRHFCPNVPIILVGNKKDLRNDENTKRE 2489

Query: 134  --ERRQVPV--DEARGKAEEWGV-QYVETSAKTRANVDKVF 169
              + +Q PV  DE R  +E+     Y+E SAKT+  V +VF
Sbjct: 2488 LMKMKQEPVRLDEGRAMSEKINAYSYLECSAKTKEGVREVF 2366
>31932
          Length = 437

 Score = 32.0 bits (71), Expect = 0.17,   Method: Compositional matrix adjust.
 Identities = 22/61 (36%), Positives = 33/61 (54%), Gaps = 1/61 (1%)
 Frame = -1

Query: 121 IPLLVVGNKSDLEERRQVPVDEARGKAEEWG-VQYVETSAKTRANVDKVFFDLMREIRAK 179
           +P L++GNKSDL   R+V  DE     +E   + + ETS K    +D+    L+ E+ AK
Sbjct: 401 VPCLLLGNKSDL-GHREVEQDEIEDLCKEHDFLGWSETSVKDGTMIDESMNYLIEEMMAK 225

Query: 180 K 180
            
Sbjct: 224 H 222
>33605
          Length = 888

 Score = 30.0 bits (66), Expect = 0.74,   Method: Compositional matrix adjust.
 Identities = 18/77 (23%), Positives = 38/77 (49%)
 Frame = +1

Query: 16  KVIMVGSGGVGKSALTLQFMYDEFVEDYEPTKADSYRKKVVLDGEEVQIDILDTAGQEDY 75
           +++M+G    GK+ +  +F   E ++   PT   + +    L+    ++++ D  GQ+  
Sbjct: 502 RLLMLGLDNAGKTTILKKF-NGEDIDTISPTLGFNIK---TLEHRGFKLNVWDVGGQQSL 669

Query: 76  AAIRDNYFRSGEGFLLV 92
            +   NYF S +G + V
Sbjct: 670 RSYWRNYFESTDGLVWV 720
>14775
          Length = 380

 Score = 29.3 bits (64), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 13/39 (33%), Positives = 22/39 (56%)
 Frame = -2

Query: 58  DGEEVQIDILDTAGQEDYAAIRDNYFRSGEGFLLVFSIT 96
           D   V+  + DT G E Y ++  ++FR  +  LLV+ +T
Sbjct: 280 DPLNVRYTLWDTGGAETYRSLWVSHFRGAQVALLVYDVT 164
>31928
          Length = 429

 Score = 28.9 bits (63), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 14/49 (28%), Positives = 29/49 (59%)
 Frame = +2

Query: 81  NYFRSGEGFLLVFSITEHESFTATAEFREQILRVKSEEDKIPLLVVGNK 129
           +Y    +GF+LV+  T  ESF    + ++ I + + + + + ++V+GNK
Sbjct: 170 HYLNFPDGFVLVYDTTSWESFRRLDKLKKDIDKHRDKRE-VHMIVIGNK 313
>22274
          Length = 1235

 Score = 27.7 bits (60), Expect = 3.0,   Method: Compositional matrix adjust.
 Identities = 10/24 (41%), Positives = 16/24 (66%)
 Frame = +1

Query: 87  EGFLLVFSITEHESFTATAEFREQ 110
           +G  ++FSI    +FT  A+FR+Q
Sbjct: 925 QGLNMIFSICNLSAFTVNADFRQQ 996
>31774
          Length = 373

 Score = 27.3 bits (59), Expect = 4.9,   Method: Compositional matrix adjust.
 Identities = 13/28 (46%), Positives = 19/28 (67%)
 Frame = +3

Query: 16  KVIMVGSGGVGKSALTLQFMYDEFVEDY 43
           +V ++G+  VGKSAL  QFM  E++  Y
Sbjct: 78  RVAVMGTVEVGKSALCRQFMSSEYLGTY 161
>10824
          Length = 1751

 Score = 26.6 bits (57), Expect = 7.4,   Method: Compositional matrix adjust.
 Identities = 16/48 (33%), Positives = 25/48 (52%)
 Frame = -3

Query: 91  LVFSITEHESFTATAEFREQILRVKSEEDKIPLLVVGNKSDLEERRQV 138
           LV  +      T T +F E   R +S    +PLLVV +K ++ E +Q+
Sbjct: 948 LVQQLQTAYQLTTTGKFAEAGDRFRSILLSVPLLVVDSKQEIAEAQQL 805
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|124494256|ref|NP_032538.2| low density lipoprotein
receptor-related protein 1 [Mus musculus]
         (4545 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

05956                                                                 171   4e-42
38381                                                                  86   9e-23
30369                                                                  59   9e-13
34993                                                                  72   6e-12
36074                                                                  50   1e-11
14418                                                                  62   5e-09
07364                                                                  60   1e-08
25877                                                                  56   3e-07
25748                                                                  56   3e-07
14371                                                                  55   7e-07
29665                                                                  55   7e-07
20820                                                                  53   2e-06
14158                                                                  52   4e-06
28816                                                                  51   9e-06
11992                                                                  51   1e-05
18708                                                                  49   3e-05
13514                                                                  45   6e-04
14599                                                                  44   0.001
34726                                                                  43   0.002
27664                                                                  43   0.002
12576                                                                  42   0.005
35170                                                                  42   0.006
19898                                                                  42   0.008
09271                                                                  41   0.011
26964                                                                  41   0.012
22430                                                                  39   0.039
30893                                                                  39   0.068
13401                                                                  37   0.18 
14910                                                                  37   0.23 
11667                                                                  36   0.29 
09839                                                                  36   0.38 
05519                                                                  35   0.58 
26257                                                                  35   0.62 
21089                                                                  34   1.2  
03773                                                                  34   1.3  
12186                                                                  34   1.3  
00070                                                                  33   1.9  
37574                                                                  33   3.1  
>05956
          Length = 1259

 Score =  171 bits (434), Expect = 4e-42,   Method: Compositional matrix adjust.
 Identities = 116/348 (33%), Positives = 168/348 (48%), Gaps = 9/348 (2%)
 Frame = +1

Query: 3002 GSYKCLCVEGYAPRGGDPHSCKAVTDEEPFLIFANRYYLRKLNLD------GSNYTLLKQ 3055
            G Y C+C   Y    GD  +C     E   L++A    +  ++        G        
Sbjct: 1    GQYVCVCNYNYR---GDGRTCTTAVREGERLLYARGSKVFSVSTSPQPGDYGQQIDFTPG 171

Query: 3056 GLNNAVALDFDYREQMIYWTDVTTQGSMIRRMHLNGSNVQVLHRTGLSNPDGLAVDWVGG 3115
             L  A+A+D D  +  +YWTD      +IR+ +L G   Q +  TGL +P+G+AVD V  
Sbjct: 172  QL--AIAVDMDCAQGQVYWTDAAA--GVIRKANLTGGPTQTVL-TGLGSPEGIAVDSVSR 336

Query: 3116 NLYWCDKGRDTIEVSKLNGAYRTVLVSSGLREPRALVVDVQNGYLYWTDWG-DHSLIGRI 3174
             LY+ D   D +  + L+G+YR  L ++ +  PRA+V+D   G +YWTDW  +   I   
Sbjct: 337  ILYYTDSKLDLVGAALLDGSYRKTLFNTDMVNPRAIVLDNNRGKIYWTDWNRNKPQIEMA 516

Query: 3175 GMDGSGRSIIVDTKITWPNGLTVDYVTERIYWADAREDYIEFASLDGSNRHVVLSQDIPH 3234
             MDGS R +++D  +  PNGL  D  ++++ WADA    +E    DG  R VV S    +
Sbjct: 517  NMDGSERRVLLDVDLRLPNGLAFDLYSQQLCWADAGTKRLECIRSDGLGRRVV-STAPSY 693

Query: 3235 IFALTLFEDYVYWTDWETKSINRAHKTTGANKTLLISTLHRPMDLHVFHALRQ--PDVPN 3292
             F++T+  + +YWTDWE K I     T G   T +   L     ++    +R   P   N
Sbjct: 694  PFSVTMLNNMLYWTDWERKDIGGVSHTGGDQVTSVSPALGGNGRMYGIAPVRDRCPRGSN 873

Query: 3293 HPCKVNNGGCSNLCLLSPGGGHKCACPTNFYLGGDGRTCVSNCTASQF 3340
              C  NNGGC+ LC  +P GG  CACP     G D R C    T+  F
Sbjct: 874  S-CAFNNGGCAFLCFPTPSGGRTCACPD----GVDPRICQQPNTS*SF 1002

 Score =  149 bits (377), Expect = 2e-35,   Method: Compositional matrix adjust.
 Identities = 100/322 (31%), Positives = 158/322 (49%), Gaps = 7/322 (2%)
 Frame = +1

Query: 1873 MCTAGYSLRSGQQACEGV---GSFLLYSVHEGIRGIPLDPNDKS-DALVPVSGTSLAVGI 1928
            +C   Y+ R   + C      G  LLY+    +  +   P        +  +   LA+ +
Sbjct: 10   VCVCNYNYRGDGRTCTTAVREGERLLYARGSKVFSVSTSPQPGDYGQQIDFTPGQLAIAV 189

Query: 1929 DFHAENDTIYWVDMGLSTISRAKRDQTWREDVVTNGIGRVEGIAVDWIAGNIYWTDQGFD 1988
            D       +YW D     I +A       + V+T G+G  EGIAVD ++  +Y+TD   D
Sbjct: 190  DMDCAQGQVYWTDAAAGVIRKANLTGGPTQTVLT-GLGSPEGIAVDSVSRILYYTDSKLD 366

Query: 1989 VIEVARLNGSFRYVVISQGLDKPRAITVHPEKGYLFWTEWG-HYPRIERSRLDGTERVVL 2047
            ++  A L+GS+R  + +  +  PRAI +   +G ++WT+W  + P+IE + +DG+ER VL
Sbjct: 367  LVGAALLDGSYRKTLFNTDMVNPRAIVLDNNRGKIYWTDWNRNKPQIEMANMDGSERRVL 546

Query: 2048 VNVSISWPNGISVDYQGGKLYWCDARMDKIERIDLETGENREVVLSSNNMDMFSVSVFED 2107
            ++V +  PNG++ D    +L W DA   ++E I  + G  R VV ++ +   FSV++  +
Sbjct: 547  LDVDLRLPNGLAFDLYSQQLCWADAGTKRLECIRSD-GLGRRVVSTAPSYP-FSVTMLNN 720

Query: 2108 FIYWSDRTHAN-GSIKRGCKDNATDSVPLRTGIGVQLKDIKVFNRDR-QKGTNVCAVANG 2165
             +YW+D    + G +     D  T   P   G G       V  RDR  +G+N CA  NG
Sbjct: 721  MLYWTDWERKDIGGVSHTGGDQVTSVSPALGGNGRMYGIAPV--RDRCPRGSNSCAFNNG 894

Query: 2166 GCQQLCLYRGGGQRACACAHGM 2187
            GC  LC     G R CAC  G+
Sbjct: 895  GCAFLCFPTPSGGRTCACPDGV 960

 Score =  145 bits (365), Expect = 4e-34,   Method: Compositional matrix adjust.
 Identities = 99/317 (31%), Positives = 148/317 (46%), Gaps = 7/317 (2%)
 Frame = +1

Query: 1258 DGESCRSLDPFKPFIIFSNRHEIRRIDL--HKGDYSV---LVPGLRNTIALDFHLSQSAL 1312
            DG +C +       ++++   ++  +      GDY       PG +  IA+D   +Q  +
Sbjct: 40   DGRTCTTAVREGERLLYARGSKVFSVSTSPQPGDYGQQIDFTPG-QLAIAVDMDCAQGQV 216

Query: 1313 YWTDVVEDKIYRGKLLDNGALTSFEVVIQYGLATPEGLAVDWIAGNIYWVESNLDQIEVA 1372
            YWTD     I +  L      T     +  GL +PEG+AVD ++  +Y+ +S LD +  A
Sbjct: 217  YWTDAAAGVIRKANLTGGPTQT-----VLTGLGSPEGIAVDSVSRILYYTDSKLDLVGAA 381

Query: 1373 KLDGTLRTTLLAGDIEHPRAIALDPRDGILFWTDWDASLPRIEAASMSGAGRRTIHRETG 1432
             LDG+ R TL   D+ +PRAI LD   G ++WTDW+ + P+IE A+M G+ RR +     
Sbjct: 382  LLDGSYRKTLFNTDMVNPRAIVLDNNRGKIYWTDWNRNKPQIEMANMDGSERRVLLDVDL 561

Query: 1433 SGGWPNGLTVDYLEKRILWIDARSDAIYSARYDGSGHMEVLRGHEFLSHPFAVTLYGGEV 1492
                PNGL  D   +++ W DA +  +   R DG G   V       S+PF+VT+    +
Sbjct: 562  R--LPNGLAFDLYSQQLCWADAGTKRLECIRSDGLGRRVV---STAPSYPFSVTMLNNML 726

Query: 1493 YWTDWRTNTLAKANKWTGHNVTVVQRTNTQPFDLQVYHPSRQ--PMAPNPCEANGGRGPC 1550
            YWTDW    +   +   G  VT V         +    P R   P   N C  N   G C
Sbjct: 727  YWTDWERKDIGGVSHTGGDQVTSVSPALGGNGRMYGIAPVRDRCPRGSNSCAFN--NGGC 900

Query: 1551 SHLCLINYNRTVSCACP 1567
            + LC    +   +CACP
Sbjct: 901  AFLCFPTPSGGRTCACP 951

 Score =  143 bits (361), Expect = 2e-33,   Method: Compositional matrix adjust.
 Identities = 97/338 (28%), Positives = 160/338 (47%), Gaps = 6/338 (1%)
 Frame = +1

Query: 3844 GGHLCSCARNFMKTHNTCKAEGSEYQVLYIADDNEIRSLFPGHPHSAYEQTFQGDESVRI 3903
            G ++C C  N+     TC     E + L  A  +++ S+        Y Q          
Sbjct: 1    GQYVCVCNYNYRGDGRTCTTAVREGERLLYARGSKVFSVSTSPQPGDYGQQIDFTPGQLA 180

Query: 3904 DAMDVHVKAGRVYWTNWHTGTISYRSLPPAAPPTTSNRHRRQIDRGVTHLNISGLKMPRG 3963
             A+D+    G+VYWT+   G I                 +  +  G T   ++GL  P G
Sbjct: 181  IAVDMDCAQGQVYWTDAAAGVI----------------RKANLTGGPTQTVLTGLGSPEG 312

Query: 3964 IAIDWVAGNVYWTDSGRDVIEVAQMKGENRKTLISGMIDEPHAIVVDPLRGTMYWSDWG- 4022
            IA+D V+  +Y+TDS  D++  A + G  RKTL +  +  P AIV+D  RG +YW+DW  
Sbjct: 313  IAVDSVSRILYYTDSKLDLVGAALLDGSYRKTLFNTDMVNPRAIVLDNNRGKIYWTDWNR 492

Query: 4023 NHPKIETAAMDGTLRETLVQDNIQWPTGLAVDYHNERLYWADAKLSVIGSIRLNGTDPIV 4082
            N P+IE A MDG+ R  L+  +++ P GLA D ++++L WADA    +  IR +G    V
Sbjct: 493  NKPQIEMANMDGSERRVLLDVDLRLPNGLAFDLYSQQLCWADAGTKRLECIRSDGLGRRV 672

Query: 4083 AADSKRGLSHPFSIDVFEDYIYGVTYINNRVFKIHKFGHSPLINLTGGLSHASDV--VLY 4140
             + +    S+PFS+ +  + +Y   +    +  +   G   + +++  L     +  +  
Sbjct: 673  VSTAP---SYPFSVTMLNNMLYWTDWERKDIGGVSHTGGDQVTSVSPALGGNGRMYGIAP 843

Query: 4141 HQHKQPEVTNPC--DRKKCEWLCLLSPSGP-VCTCPNG 4175
             + + P  +N C  +   C +LC  +PSG   C CP+G
Sbjct: 844  VRDRCPRGSNSCAFNNGGCAFLCFPTPSGGRTCACPDG 957

 Score =  126 bits (316), Expect = 2e-28,   Method: Compositional matrix adjust.
 Identities = 90/276 (32%), Positives = 136/276 (49%), Gaps = 7/276 (2%)
 Frame = +1

Query: 564 ALDFHAETGFIYFADTTSYLIGRQKIDGTERETILKDGIHNVEGVAVDWMGDNLYWTDDG 623
           A+D     G +Y+ D  + +I +  + G   +T+L  G+ + EG+AVD +   LY+TD  
Sbjct: 184 AVDMDCAQGQVYWTDAAAGVIRKANLTGGPTQTVLT-GLGSPEGIAVDSVSRILYYTDS- 357

Query: 624 PKKTISVARLEKAAQTRKTLIEGKMTHPRAIVVDPLNGWMYWTDWEEDPKDSRRGRLERA 683
               +  A L+     RKTL    M +PRAIV+D   G +YWTDW  +     + ++E A
Sbjct: 358 KLDLVGAALLD--GSYRKTLFNTDMVNPRAIVLDNNRGKIYWTDWNRN-----KPQIEMA 516

Query: 684 WMDGSHRDIFVTSKTVLWPNGLSLDIPAGRLYWVDAFYDRIETILLNGTDRKIVYEGPEL 743
            MDGS R + +     L PNGL+ D+ + +L W DA   R+E I  +G  R++V   P  
Sbjct: 517 NMDGSERRVLLDVDLRL-PNGLAFDLYSQQLCWADAGTKRLECIRSDGLGRRVVSTAP-- 687

Query: 744 NHAFGLCHHGNYLFWTEYRSGSVYRLERGVAGAPPTVTLLRSERPPIF--EIRMYDAQQQ 801
           ++ F +    N L+WT++         + + G   T     +   P      RMY     
Sbjct: 688 SYPFSVTMLNNMLYWTDWE-------RKDIGGVSHTGGDQVTSVSPALGGNGRMYGIAPV 846

Query: 802 Q----VGTNKCRVNNGGCSSLCLATP-GSRQCACAE 832
           +     G+N C  NNGGC+ LC  TP G R CAC +
Sbjct: 847 RDRCPRGSNSCAFNNGGCAFLCFPTPSGGRTCACPD 954

 Score =  124 bits (311), Expect = 1e-27,   Method: Compositional matrix adjust.
 Identities = 100/319 (31%), Positives = 147/319 (46%), Gaps = 10/319 (3%)
 Frame = +1

Query: 1577 TTCYEFKKFLLYARQMEIRGVDLDAPY--YNYIISFTVPDIDNVTVLDYDAREQRVYWSD 1634
            TT     + LLYAR  ++  V        Y   I FT   +     +D D  + +VYW+D
Sbjct: 55   TTAVREGERLLYARGSKVFSVSTSPQPGDYGQQIDFTPGQL--AIAVDMDCAQGQVYWTD 228

Query: 1635 VRTQAIKRAFINGTGVETVVSADLPNAHGLAVDWVSRNLFWTSYDTNKKQINVARLDGSF 1694
                 I++A + G   +TV++  L +  G+AVD VSR L++T  D+    +  A LDGS+
Sbjct: 229  AAAGVIRKANLTGGPTQTVLTG-LGSPEGIAVDSVSRILYYT--DSKLDLVGAALLDGSY 399

Query: 1695 KNAVVQG-LEQPHGLVVHPLRGKLYWTDGD----NISMANMDGSNHTLLFS-GQKGPVGL 1748
            +  +    +  P  +V+   RGK+YWTD +     I MANMDGS   +L     + P GL
Sbjct: 400  RKTLFNTDMVNPRAIVLDNNRGKIYWTDWNRNKPQIEMANMDGSERRVLLDVDLRLPNGL 579

Query: 1749 AIDFPESKLYWISSGNHTINRCNLDGSELEVIDTMRSQLGKATALAIMGDKLWWADQVSE 1808
            A D    +L W  +G   +     DG    V+ T  S     T L  M   L+W D   +
Sbjct: 580  AFDLYSQQLCWADAGTKRLECIRSDGLGRRVVSTAPSYPFSVTMLNNM---LYWTDWERK 750

Query: 1809 KMGTCNKADGSGSVVLRNSTTLVMHMKVYDESIQLEH--EGTNPCSVNNGDCSQLCLPTS 1866
             +G  +     G  V   S  L  + ++Y  +   +    G+N C+ NNG C+ LC PT 
Sbjct: 751  DIGGVSHT--GGDQVTSVSPALGGNGRMYGIAPVRDRCPRGSNSCAFNNGGCAFLCFPTP 924

Query: 1867 ETTRSCMCTAGYSLRSGQQ 1885
               R+C C  G   R  QQ
Sbjct: 925  SGGRTCACPDGVDPRICQQ 981

 Score =  110 bits (275), Expect = 1e-23,   Method: Compositional matrix adjust.
 Identities = 93/347 (26%), Positives = 151/347 (43%), Gaps = 9/347 (2%)
 Frame = +1

Query: 2177 GQRACACAHGMLAEDGASC----REYAGYLLYSERTILKSIHLSDERNLNAPVQPFEDPE 2232
            GQ  C C +     DG +C    RE    LLY+  + + S+  S +     P    +  +
Sbjct: 1    GQYVCVCNYNYRG-DGRTCTTAVRE-GERLLYARGSKVFSVSTSPQ-----PGDYGQQID 159

Query: 2233 HMKNVIALAFDYRAGTSPGTPNRIFFSDIHFGNIQQINDDGSGRTTIVENVGSVEGLAYH 2292
                 +A+A D           +++++D   G I++ N  G    T++  +GS EG+A  
Sbjct: 160  FTPGQLAIAVDMDCAQG-----QVYWTDAAAGVIRKANLTGGPTQTVLTGLGSPEGIAVD 324

Query: 2293 RGWDXXXXXXXXXXXXXXXXVDQT-RPGAFERETVITMSGDDHPRAFVLDECQNLMFWTN 2351
                                +D + R   F  + V       +PRA VLD  +  ++WT+
Sbjct: 325  SVSRILYYTDSKLDLVGAALLDGSYRKTLFNTDMV-------NPRAIVLDNNRGKIYWTD 483

Query: 2352 WNELHPSIMRAALSGANVLTLIEKDIRTPNGLAIDHRAEKLYFSDATLDKIERCEYDGSH 2411
            WN   P I  A + G+    L++ D+R PNGLA D  +++L ++DA   ++E    DG  
Sbjct: 484  WNRNKPQIEMANMDGSERRVLLDVDLRLPNGLAFDLYSQQLCWADAGTKRLECIRSDGLG 663

Query: 2412 RYVILKSEPVHPFGLAVYGEHIFWTDWVRRAVQRANKYVGSDMKLLRVDIPQQP-MGIIA 2470
            R V+  + P +PF + +    ++WTDW R+ +   +   G  +  +   +     M  IA
Sbjct: 664  RRVV-STAPSYPFSVTMLNNMLYWTDWERKDIGGVSHTGGDQVTSVSPALGGNGRMYGIA 840

Query: 2471 VANDTNSCELSPCRINNGGCQDLCLLTHQGHVNCSCRGG---RILQE 2514
               D      + C  NNGGC  LC  T  G   C+C  G   RI Q+
Sbjct: 841  PVRDRCPRGSNSCAFNNGGCAFLCFPTPSGGRTCACPDGVDPRICQQ 981

 Score = 89.0 bits (219), Expect = 4e-17,   Method: Compositional matrix adjust.
 Identities = 92/366 (25%), Positives = 148/366 (40%), Gaps = 12/366 (3%)
 Frame = +1

Query: 170 GSFTCGCVEGYLLQPDNRSCKAKNEPVDRPPVLLIANSQNILATYLS---GAQVSXXXXX 226
           G + C C   Y  + D R+C       +R   LL A    + +   S   G         
Sbjct: 1   GQYVCVC--NYNYRGDGRTCTTAVREGER---LLYARGSKVFSVSTSPQPGDYGQQIDFT 165

Query: 227 XXXXXXAMDFSYANETVCWVHVGDSAAQTQLKCARMPGLKGFVDEHTINISLSLHHVEQM 286
                 A+D   A   V W      AA   ++ A + G        T  +   L   E +
Sbjct: 166 PGQLAIAVDMDCAQGQVYWTD----AAAGVIRKANLTG------GPTQTVLTGLGSPEGI 315

Query: 287 AIDWLTGNFYFVDDIDDRIFVCNRNGDTCVTLLDLELYNPKGIALDPAMGKVFFTDYGQ- 345
           A+D ++   Y+ D   D +     +G    TL + ++ NP+ I LD   GK+++TD+ + 
Sbjct: 316 AVDSVSRILYYTDSKLDLVGAALLDGSYRKTLFNTDMVNPRAIVLDNNRGKIYWTDWNRN 495

Query: 346 IPKVERCDMDGQNRTKLVDSKIVFPHGITLDLVSRLVYWADAYLDYIEVVDYEGKGRQTI 405
            P++E  +MDG  R  L+D  +  P+G+  DL S+ + WADA    +E +  +G GR+ +
Sbjct: 496 KPQIEMANMDGSERRVLLDVDLRLPNGLAFDLYSQQLCWADAGTKRLECIRSDGLGRRVV 675

Query: 406 IQGILIEHLYGLTVFENYLYATNSDNANT--------QQKTSVIRVNRFNSTEYQVVTRV 457
                  + + +T+  N LY T+ +  +          Q TSV      N   Y +    
Sbjct: 676 --STAPSYPFSVTMLNNMLYWTDWERKDIGGVSHTGGDQVTSVSPALGGNGRMYGIAPVR 849

Query: 458 DKGGALHIYHQRRQPRVRSHACENDQYGKPGGCSDICLLANSHKARTCRCRSGFSLGSDG 517
           D           R PR  +    N+     GGC+ +C    S   RTC C  G     D 
Sbjct: 850 D-----------RCPRGSNSCAFNN-----GGCAFLCFPTPSG-GRTCACPDGV----DP 966

Query: 518 KSCKKP 523
           + C++P
Sbjct: 967 RICQQP 984

 Score = 32.7 bits (73), Expect = 3.0,   Method: Compositional matrix adjust.
 Identities = 13/29 (44%), Positives = 18/29 (62%)
 Frame = +1

Query: 1186 CSLNNGGCSHNCSVAPGEGIVCSCPLGME 1214
            C+ NNGGC+  C   P  G  C+CP G++
Sbjct: 877  CAFNNGGCAFLCFPTPSGGRTCACPDGVD 963
>38381
          Length = 658

 Score = 67.8 bits (164), Expect(3) = 9e-23,   Method: Compositional matrix adjust.
 Identities = 46/107 (42%), Positives = 58/107 (54%)
 Frame = +1

Query: 3380 FQCSTGICTNPAFICDGDNDCQDNSDEANCDIHVCLPSQFKCTNTNRCIPGIFRCNGQDN 3439
            F+C  G C +    CDG  DC D SDE+NC    C   QF C +   CI   FRCNG+  
Sbjct: 4    FECEDGSCIDNRLRCDGVPDCSDRSDESNC---PCRDDQFSCRD-GLCIEAEFRCNGRVE 171

Query: 3440 CGDGEDERDCPEVTCAPNQFQCSITKRCIPRVWVCDRDNDCVDGSDE 3486
            C DG DE +CP  TC+  +F C    +C+     C++  DC DGSDE
Sbjct: 172  CEDGSDEEECPRRTCSFAEFTCD-DGQCVDLRDQCNQVTDCQDGSDE 309

 Score = 53.1 bits (126), Expect(3) = 9e-23,   Method: Compositional matrix adjust.
 Identities = 31/66 (46%), Positives = 38/66 (57%)
 Frame = +2

Query: 3546 NNRCVPGRWQCDYDNDCGDNSDEESCTPRPCSESEFSCANGRCIAGRWKCDGDHDCADGS 3605
            + RC+P   +CD   DC D SDEE C    C  +EF C +G C+  R KCD   +C DGS
Sbjct: 458  DGRCIPDSRKCDRRRDCADGSDEEECEG-VCGRNEFRCNDGTCVERRVKCDRFVNCPDGS 634

Query: 3606 DEKDCT 3611
            DE DC 
Sbjct: 635  DEFDCA 652

 Score = 27.3 bits (59), Expect(3) = 9e-23,   Method: Composition-based stats.
 Identities = 9/18 (50%), Positives = 14/18 (77%)
 Frame = +3

Query: 3492 QMTCGVDEFRCKDSGRCI 3509
            +++C  D+F C+DSG CI
Sbjct: 312  ELSCRDDQFTCQDSGLCI 365

 Score = 86.3 bits (212), Expect(2) = 2e-22,   Method: Compositional matrix adjust.
 Identities = 53/121 (43%), Positives = 64/121 (52%)
 Frame = +1

Query: 2530 EFECANGECISFSLTCDGVSHCKDKSDEKPSYCNSRRCKKTFRQCNNGRCVSNMLWCNGV 2589
            +FEC +G CI   L CDGV  C D+SDE  S C    C+     C +G C+     CNG 
Sbjct: 1    DFECEDGSCIDNRLRCDGVPDCSDRSDE--SNCP---CRDDQFSCRDGLCIEAEFRCNGR 165

Query: 2590 DDCGDGSDEIPCNKTACGVGEFRCRDGSCIGNSSRCNQFVDCEDASDEMNCSTTDCSSYF 2649
             +C DGSDE  C +  C   EF C DG C+    +CNQ  DC+D SDE NC     SS  
Sbjct: 166  VECEDGSDEEECPRRTCSFAEFTCDDGQCVDLRDQCNQVTDCQDGSDEKNCPAEMISSRV 345

Query: 2650 R 2650
            R
Sbjct: 346  R 348

 Score = 41.2 bits (95), Expect(2) = 2e-22,   Method: Compositional matrix adjust.
 Identities = 26/65 (40%), Positives = 31/65 (47%)
 Frame = +2

Query: 2667 CYAPSWVCDGANDCGDYSDERDCPGVKRPRCPLNYFACPSGRCIPMSWTCDKEDDCENGE 2726
            C   S  CD   DC D SDE +C GV    C  N F C  G C+     CD+  +C +G 
Sbjct: 467  CIPDSRKCDRRRDCADGSDEEECEGV----CGRNEFRCNDGTCVERRVKCDRFVNCPDGS 634

Query: 2727 DETHC 2731
            DE  C
Sbjct: 635  DEFDC 649

 Score = 83.2 bits (204), Expect(3) = 2e-20,   Method: Compositional matrix adjust.
 Identities = 47/108 (43%), Positives = 66/108 (61%), Gaps = 1/108 (0%)
 Frame = +1

Query: 3542 FRCKNNRCVPGRWQCDYDNDCGDNSDEESCTPRPCSESEFSCANGRCIAGRWKCDGDHDC 3601
            F C++  C+  R +CD   DC D SDE +C   PC + +FSC +G CI   ++C+G  +C
Sbjct: 4    FECEDGSCIDNRLRCDGVPDCSDRSDESNC---PCRDDQFSCRDGLCIEAEFRCNGRVEC 174

Query: 3602 ADGSDEKDCTPR-CDMDQFQCKSGHCIPLRWRCDADADCMDGSDEEAC 3648
             DGSDE++C  R C   +F C  G C+ LR +C+   DC DGSDE+ C
Sbjct: 175  EDGSDEEECPRRTCSFAEFTCDDGQCVDLRDQCNQVTDCQDGSDEKNC 318

 Score = 35.0 bits (79), Expect(3) = 2e-20,   Method: Compositional matrix adjust.
 Identities = 19/56 (33%), Positives = 30/56 (53%)
 Frame = +2

Query: 3710 CLWIGRQCDGVDNCGDGTDEEDCEPPTAQNPHCKDKKEFLCRNQRCLSSSLRCNMF 3765
            C+   R+CD   +C DG+DEE+CE    +N       EF C +  C+   ++C+ F
Sbjct: 467  CIPDSRKCDRRRDCADGSDEEECEGVCGRN-------EFRCNDGTCVERRVKCDRF 613

 Score = 22.3 bits (46), Expect(3) = 2e-20,   Method: Composition-based stats.
 Identities = 23/52 (44%), Positives = 28/52 (53%), Gaps = 1/52 (1%)
 Frame = +3

Query: 3654 TCPLDEFQCNNT-LCKPLAWKCDGEDDCGDNSDENPEECARFICPPNRPFRC 3704
            +C  D+F C ++ LC  LA +CD   DC D SDE  E C    C  N  FRC
Sbjct: 318  SCRDDQFTCQDSGLCIDLARRCDRRRDCEDGSDE--ERCP---CLANE-FRC 455

 Score = 58.9 bits (141), Expect(3) = 7e-18,   Method: Compositional matrix adjust.
 Identities = 32/74 (43%), Positives = 47/74 (63%)
 Frame = +1

Query: 3537 CEPYQFRCKNNRCVPGRWQCDYDNDCGDNSDEESCTPRPCSESEFSCANGRCIAGRWKCD 3596
            C   QF C++  C+   ++C+   +C D SDEE C  R CS +EF+C +G+C+  R +C+
Sbjct: 97   CRDDQFSCRDGLCIEAEFRCNGRVECEDGSDEEECPRRTCSFAEFTCDDGQCVDLRDQCN 276

Query: 3597 GDHDCADGSDEKDC 3610
               DC DGSDEK+C
Sbjct: 277  QVTDCQDGSDEKNC 318

 Score = 38.1 bits (87), Expect(3) = 7e-18,   Method: Compositional matrix adjust.
 Identities = 32/66 (48%), Positives = 37/66 (56%)
 Frame = +2

Query: 3667 CKPLAWKCDGEDDCGDNSDENPEECARFICPPNRPFRCKNDRVCLWIGRQCDGVDNCGDG 3726
            C P + KCD   DC D SDE  EEC   +C  N  FRC ND  C+    +CD   NC DG
Sbjct: 467  CIPDSRKCDRRRDCADGSDE--EECE-GVCGRN-EFRC-NDGTCVERRVKCDRFVNCPDG 631

Query: 3727 TDEEDC 3732
            +DE DC
Sbjct: 632  SDEFDC 649

 Score = 34.3 bits (77), Expect(3) = 7e-18,   Method: Composition-based stats.
 Identities = 26/50 (52%), Positives = 29/50 (58%), Gaps = 1/50 (2%)
 Frame = +3

Query: 3614 CDMDQFQCK-SGHCIPLRWRCDADADCMDGSDEEACGTGVRTCPLDEFQC 3662
            C  DQF C+ SG CI L  RCD   DC DGSDEE C      C  +EF+C
Sbjct: 321  CRDDQFTCQDSGLCIDLARRCDRRRDCEDGSDEERC-----PCLANEFRC 455

 Score = 57.8 bits (138), Expect(3) = 4e-17,   Method: Compositional matrix adjust.
 Identities = 31/65 (47%), Positives = 40/65 (61%)
 Frame = +2

Query: 3585 NGRCIAGRWKCDGDHDCADGSDEKDCTPRCDMDQFQCKSGHCIPLRWRCDADADCMDGSD 3644
            +GRCI    KCD   DCADGSDE++C   C  ++F+C  G C+  R +CD   +C DGSD
Sbjct: 458  DGRCIPDSRKCDRRRDCADGSDEEECEGVCGRNEFRCNDGTCVERRVKCDRFVNCPDGSD 637

Query: 3645 EEACG 3649
            E  C 
Sbjct: 638  EFDCA 652

 Score = 43.1 bits (100), Expect(3) = 4e-17,   Method: Compositional matrix adjust.
 Identities = 36/94 (38%), Positives = 49/94 (52%)
 Frame = +1

Query: 3419 FKCTNTNRCIPGIFRCNGQDNCGDGEDERDCPEVTCAPNQFQCSITKRCIPRVWVCDRDN 3478
            F+C + + CI    RC+G  +C D  DE +CP   C  +QF C     CI   + C+   
Sbjct: 4    FECEDGS-CIDNRLRCDGVPDCSDRSDESNCP---CRDDQFSCR-DGLCIEAEFRCNGRV 168

Query: 3479 DCVDGSDEPANCTQMTCGVDEFRCKDSGRCIPAR 3512
            +C DGSDE   C + TC   EF C D G+C+  R
Sbjct: 169  ECEDGSDE-EECPRRTCSFAEFTC-DDGQCVDLR 264

 Score = 27.7 bits (60), Expect(3) = 4e-17,   Method: Composition-based stats.
 Identities = 21/52 (40%), Positives = 28/52 (53%), Gaps = 1/52 (1%)
 Frame = +3

Query: 3534 ERTCEPYQFRCKNN-RCVPGRWQCDYDNDCGDNSDEESCTPRPCSESEFSCA 3584
            E +C   QF C+++  C+    +CD   DC D SDEE C   PC  +EF C 
Sbjct: 312  ELSCRDDQFTCQDSGLCIDLARRCDRRRDCEDGSDEERC---PCLANEFRCG 458

 Score = 79.0 bits (193), Expect(2) = 8e-16,   Method: Compositional matrix adjust.
 Identities = 49/107 (45%), Positives = 62/107 (57%)
 Frame = +1

Query: 3580 EFSCANGRCIAGRWKCDGDHDCADGSDEKDCTPRCDMDQFQCKSGHCIPLRWRCDADADC 3639
            +F C +G CI  R +CDG  DC+D SDE +C  R   DQF C+ G CI   +RC+   +C
Sbjct: 1    DFECEDGSCIDNRLRCDGVPDCSDRSDESNCPCR--DDQFSCRDGLCIEAEFRCNGRVEC 174

Query: 3640 MDGSDEEACGTGVRTCPLDEFQCNNTLCKPLAWKCDGEDDCGDNSDE 3686
             DGSDEE C    RTC   EF C++  C  L  +C+   DC D SDE
Sbjct: 175  EDGSDEEECPR--RTCSFAEFTCDDGQCVDLRDQCNQVTDCQDGSDE 309

 Score = 26.2 bits (56), Expect(2) = 8e-16,   Method: Composition-based stats.
 Identities = 19/50 (38%), Positives = 27/50 (54%)
 Frame = +3

Query: 3702 FRCKNDRVCLWIGRQCDGVDNCGDGTDEEDCEPPTAQNPHCKDKKEFLCR 3751
            F C++  +C+ + R+CD   +C DG+DEE C P  A    C     FL R
Sbjct: 336  FTCQDSGLCIDLARRCDRRRDCEDGSDEERC-PCLANEFRCGTVAAFLIR 482

 Score = 50.4 bits (119), Expect(3) = 2e-14,   Method: Compositional matrix adjust.
 Identities = 34/61 (55%), Positives = 39/61 (63%)
 Frame = +2

Query: 2831 CIPKHFVCDHDRDCADGSDESPECEYPTCGPNEFRCANGRCLSSRQWECDGENDCHDHSD 2890
            CIP    CD  RDCADGSDE  ECE   CG NEFRC +G C+  R+ +CD   +C D SD
Sbjct: 467  CIPDSRKCDRRRDCADGSDEE-ECE-GVCGRNEFRCNDGTCV-ERRVKCDRFVNCPDGSD 637

Query: 2891 E 2891
            E
Sbjct: 638  E 640

 Score = 49.3 bits (116), Expect(3) = 2e-14,   Method: Compositional matrix adjust.
 Identities = 31/83 (37%), Positives = 43/83 (51%), Gaps = 1/83 (1%)
 Frame = +1

Query: 2667 CYAPSWVCDGANDCGDYSDERDCPGVKRPRCPLNYFACPSGRCIPMSWTCDKEDDCENGE 2726
            C      CDG  DC D SDE +CP      C  + F+C  G CI   + C+   +CE+G 
Sbjct: 25   CIDNRLRCDGVPDCSDRSDESNCP------CRDDQFSCRDGLCIEAEFRCNGRVECEDGS 186

Query: 2727 DETHC-NKFCSEAQFECQNHRCI 2748
            DE  C  + CS A+F C + +C+
Sbjct: 187  DEEECPRRTCSFAEFTCDDGQCV 255

 Score = 19.6 bits (39), Expect(3) = 2e-14,   Method: Composition-based stats.
 Identities = 18/53 (33%), Positives = 25/53 (47%)
 Frame = +3

Query: 2774 TCGPSSFSCPGTHVCVPERWLCDGDKDCTDGADESVTAGCLYNSTCDDREFMC 2826
            +C    F+C  + +C+     CD  +DC DG+DE     CL N      EF C
Sbjct: 318  SCRDDQFTCQDSGLCIDLARRCDRRRDCEDGSDEE-RCPCLAN------EFRC 455

 Score = 64.3 bits (155), Expect(2) = 1e-12,   Method: Compositional matrix adjust.
 Identities = 43/111 (38%), Positives = 60/111 (54%)
 Frame = +1

Query: 3340 FVCKNDKCIPFWWKCDTEDDCGDHSDEPPDCPEFKCRPGQFQCSTGICTNPAFICDGDND 3399
            F C++  CI    +CD   DC D SDE  +CP   CR  QF C  G+C    F C+G  +
Sbjct: 4    FECEDGSCIDNRLRCDGVPDCSDRSDES-NCP---CRDDQFSCRDGLCIEAEFRCNGRVE 171

Query: 3400 CQDNSDEANCDIHVCLPSQFKCTNTNRCIPGIFRCNGQDNCGDGEDERDCP 3450
            C+D SDE  C    C  ++F C +  +C+    +CN   +C DG DE++CP
Sbjct: 172  CEDGSDEEECPRRTCSFAEFTC-DDGQCVDLRDQCNQVTDCQDGSDEKNCP 321

 Score = 29.6 bits (65), Expect(2) = 1e-12,   Method: Composition-based stats.
 Identities = 22/52 (42%), Positives = 28/52 (53%)
 Frame = +3

Query: 3451 EVTCAPNQFQCSITKRCIPRVWVCDRDNDCVDGSDEPANCTQMTCGVDEFRC 3502
            E++C  +QF C  +  CI     CDR  DC DGSDE     +  C  +EFRC
Sbjct: 312  ELSCRDDQFTCQDSGLCIDLARRCDRRRDCEDGSDE----ERCPCLANEFRC 455

 Score = 54.3 bits (129), Expect(3) = 2e-12,   Method: Compositional matrix adjust.
 Identities = 34/93 (36%), Positives = 46/93 (49%)
 Frame = +1

Query: 901 FKCENNRCIPNRWLCDGDNDCGNSEDESNATCSARTCPPNQFSCASGRCIPISWTCXXXX 960
           F+CE+  CI NR  CDG  DC +  DESN  C       +QFSC  G CI   + C    
Sbjct: 4   FECEDGSCIDNRLRCDGVPDCSDRSDESNCPCR-----DDQFSCRDGLCIEAEFRCNGRV 168

Query: 961 XXXXXXXESASCAYPTCFPLTQFTCNNGRCINI 993
                  E   C   TC    +FTC++G+C+++
Sbjct: 169 ECEDGSDEE-ECPRRTC-SFAEFTCDDGQCVDL 261

 Score = 36.6 bits (83), Expect(3) = 2e-12,   Method: Compositional matrix adjust.
 Identities = 25/55 (45%), Positives = 30/55 (54%)
 Frame = +2

Query: 1073 DGLCIPLRWRCDGDTDCMDSSDEKSCEGVTHVCDPNVKFGCKDSARCISKAWVCD 1127
            DG CIP   +CD   DC D SDE+ CEG   VC  N +F C D   C+ +   CD
Sbjct: 458  DGRCIPDSRKCDRRRDCADGSDEEECEG---VCGRN-EFRCNDGT-CVERRVKCD 607

 Score = 21.6 bits (44), Expect(3) = 2e-12,   Method: Composition-based stats.
 Identities = 23/57 (40%), Positives = 27/57 (47%), Gaps = 1/57 (1%)
 Frame = +3

Query: 1015 SCSSTQFKC-NSGRCIPEHWTCDGDNDCGDYSDETHANCTNQATRPPGGCHSDEFQC 1070
            SC   QF C +SG CI     CD   DC D SDE          R P  C ++EF+C
Sbjct: 318  SCRDDQFTCQDSGLCIDLARRCDRRRDCEDGSDE---------ERCP--CLANEFRC 455

 Score = 63.2 bits (152), Expect(2) = 5e-11,   Method: Compositional matrix adjust.
 Identities = 47/119 (39%), Positives = 56/119 (47%)
 Frame = +1

Query: 2573 QCNNGRCVSNMLWCNGVDDCGDGSDEIPCNKTACGVGEFRCRDGSCIGNSSRCNQFVDCE 2632
            +C +G C+ N L C+GV DC D SDE  C    C   +F CRDG CI    RCN  V+CE
Sbjct: 7    ECEDGSCIDNRLRCDGVPDCSDRSDESNC---PCRDDQFSCRDGLCIEAEFRCNGRVECE 177

Query: 2633 DASDEMNCSTTDCSSYFRLGVKGVLFQPCERTSLCYAPSWVCDGANDCGDYSDERDCPG 2691
            D SDE  C    CS        G           C      C+   DC D SDE++CP 
Sbjct: 178  DGSDEEECPRRTCSFAEFTCDDG----------QCVDLRDQCNQVTDCQDGSDEKNCPA 324

 Score = 25.4 bits (54), Expect(2) = 5e-11,   Method: Composition-based stats.
 Identities = 20/51 (39%), Positives = 26/51 (50%), Gaps = 1/51 (1%)
 Frame = +3

Query: 2693 KRPRCPLNYFACP-SGRCIPMSWTCDKEDDCENGEDETHCNKFCSEAQFEC 2742
            K   C  + F C  SG CI ++  CD+  DCE+G DE  C   C   +F C
Sbjct: 309  KELSCRDDQFTCQDSGLCIDLARRCDRRRDCEDGSDEERCP--CLANEFRC 455

 Score = 41.6 bits (96), Expect(3) = 1e-10,   Method: Compositional matrix adjust.
 Identities = 34/106 (32%), Positives = 47/106 (44%)
 Frame = +1

Query: 2702 FACPSGRCIPMSWTCDKEDDCENGEDETHCNKFCSEAQFECQNHRCISKQWLXXXXXXXX 2761
            F C  G CI     CD   DC +  DE++C   C + QF C++  CI  ++         
Sbjct: 4    FECEDGSCIDNRLRCDGVPDCSDRSDESNCP--CRDDQFSCRDGLCIEAEFRCNGRVECE 177

Query: 2762 XXXXEAAHCEGKTCGPSSFSCPGTHVCVPERWLCDGDKDCTDGADE 2807
                E   C  +TC  + F+C     CV  R  C+   DC DG+DE
Sbjct: 178  DGSDE-EECPRRTCSFAEFTCDDGQ-CVDLRDQCNQVTDCQDGSDE 309

 Score = 33.5 bits (75), Expect(3) = 1e-10,   Method: Compositional matrix adjust.
 Identities = 26/76 (34%), Positives = 35/76 (46%)
 Frame = +2

Query: 2868 NGRCLSSRQWECDGENDCHDHSDEAPKNPHCTSPEHKCNASSQFLCSSGRCVAEALLCNG 2927
            +GRC+     +CD   DC D SDE      C          ++F C+ G CV   + C+ 
Sbjct: 458  DGRCIPD-SRKCDRRRDCADGSDEEECEGVC--------GRNEFRCNDGTCVERRVKCDR 610

Query: 2928 QDDCGDGSDERGCHVN 2943
              +C DGSDE  C  N
Sbjct: 611  FVNCPDGSDEFDCACN 658

 Score = 31.6 bits (70), Expect(3) = 1e-10,   Method: Composition-based stats.
 Identities = 25/51 (49%), Positives = 28/51 (54%), Gaps = 1/51 (1%)
 Frame = +3

Query: 2818 TCDDREFMCQNR-LCIPKHFVCDHDRDCADGSDESPECEYPTCGPNEFRCA 2867
            +C D +F CQ+  LCI     CD  RDC DGSDE    E   C  NEFRC 
Sbjct: 318  SCRDDQFTCQDSGLCIDLARRCDRRRDCEDGSDE----ERCPCLANEFRCG 458

 Score = 66.6 bits (161), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 45/122 (36%), Positives = 59/122 (48%)
 Frame = +1

Query: 2610 EFRCRDGSCIGNSSRCNQFVDCEDASDEMNCSTTDCSSYFRLGVKGVLFQPCERTSLCYA 2669
            +F C DGSCI N  RC+   DC D SDE NC   D    F             R  LC  
Sbjct: 1    DFECEDGSCIDNRLRCDGVPDCSDRSDESNCPCRD--DQFSC-----------RDGLCIE 141

Query: 2670 PSWVCDGANDCGDYSDERDCPGVKRPRCPLNYFACPSGRCIPMSWTCDKEDDCENGEDET 2729
              + C+G  +C D SDE +CP   R  C    F C  G+C+ +   C++  DC++G DE 
Sbjct: 142  AEFRCNGRVECEDGSDEEECP---RRTCSFAEFTCDDGQCVDLRDQCNQVTDCQDGSDEK 312

Query: 2730 HC 2731
            +C
Sbjct: 313  NC 318

 Score = 59.3 bits (142), Expect(2) = 5e-10,   Method: Compositional matrix adjust.
 Identities = 30/66 (45%), Positives = 43/66 (65%)
 Frame = +2

Query: 2576 NGRCVSNMLWCNGVDDCGDGSDEIPCNKTACGVGEFRCRDGSCIGNSSRCNQFVDCEDAS 2635
            +GRC+ +   C+   DC DGSDE  C +  CG  EFRC DG+C+    +C++FV+C D S
Sbjct: 458  DGRCIPDSRKCDRRRDCADGSDEEEC-EGVCGRNEFRCNDGTCVERRVKCDRFVNCPDGS 634

Query: 2636 DEMNCS 2641
            DE +C+
Sbjct: 635  DEFDCA 652

 Score = 26.2 bits (56), Expect(2) = 5e-10,   Method: Composition-based stats.
 Identities = 20/47 (42%), Positives = 25/47 (53%), Gaps = 3/47 (6%)
 Frame = +3

Query: 2524 SCRAQDEFECAN-GECISFSLTCDGVSHCKDKSDEK--PSYCNSRRC 2567
            SCR  D+F C + G CI  +  CD    C+D SDE+  P   N  RC
Sbjct: 318  SCR-DDQFTCQDSGLCIDLARRCDRRRDCEDGSDEERCPCLANEFRC 455

 Score = 43.1 bits (100), Expect(3) = 6e-10,   Method: Compositional matrix adjust.
 Identities = 27/61 (44%), Positives = 37/61 (60%)
 Frame = +2

Query: 3426 RCIPGIFRCNGQDNCGDGEDERDCPEVTCAPNQFQCSITKRCIPRVWVCDRDNDCVDGSD 3485
            RCIP   +C+ + +C DG DE +C E  C  N+F+C+    C+ R   CDR  +C DGSD
Sbjct: 464  RCIPDSRKCDRRRDCADGSDEEEC-EGVCGRNEFRCNDGT-CVERRVKCDRFVNCPDGSD 637

Query: 3486 E 3486
            E
Sbjct: 638  E 640

 Score = 35.0 bits (79), Expect(3) = 6e-10,   Method: Composition-based stats.
 Identities = 22/51 (43%), Positives = 29/51 (56%), Gaps = 1/51 (1%)
 Frame = +3

Query: 3372 EFKCRPGQFQCS-TGICTNPAFICDGDNDCQDNSDEANCDIHVCLPSQFKC 3421
            E  CR  QF C  +G+C + A  CD   DC+D SDE  C    CL ++F+C
Sbjct: 312  ELSCRDDQFTCQDSGLCIDLARRCDRRRDCEDGSDEERCP---CLANEFRC 455

 Score = 25.8 bits (55), Expect(3) = 6e-10,   Method: Compositional matrix adjust.
 Identities = 24/87 (27%), Positives = 40/87 (45%), Gaps = 2/87 (2%)
 Frame = +1

Query: 3287 QPDVPNHPCKVNNGGCSN-LCLLSPGGGHKCACPTNFYLGGDGRTC-VSNCTASQFVCKN 3344
            + D  N PC+ +   C + LC+ +     +C        G D   C    C+ ++F C +
Sbjct: 73   RSDESNCPCRDDQFSCRDGLCIEAE---FRCNGRVECEDGSDEEECPRRTCSFAEFTCDD 243

Query: 3345 DKCIPFWWKCDTEDDCGDHSDEPPDCP 3371
             +C+    +C+   DC D SDE  +CP
Sbjct: 244  GQCVDLRDQCNQVTDCQDGSDE-KNCP 321

 Score = 60.8 bits (146), Expect(2) = 2e-09,   Method: Compositional matrix adjust.
 Identities = 44/104 (42%), Positives = 57/104 (54%)
 Frame = +1

Query: 2788 CVPERWLCDGDKDCTDGADESVTAGCLYNSTCDDREFMCQNRLCIPKHFVCDHDRDCADG 2847
            C+  R  CDG  DC+D +DES       N  C D +F C++ LCI   F C+   +C DG
Sbjct: 25   CIDNRLRCDGVPDCSDRSDES-------NCPCRDDQFSCRDGLCIEAEFRCNGRVECEDG 183

Query: 2848 SDESPECEYPTCGPNEFRCANGRCLSSRQWECDGENDCHDHSDE 2891
            SDE  EC   TC   EF C +G+C+  R  +C+   DC D SDE
Sbjct: 184  SDEE-ECPRRTCSFAEFTCDDGQCVDLRD-QCNQVTDCQDGSDE 309

 Score = 22.7 bits (47), Expect(2) = 2e-09,   Method: Composition-based stats.
 Identities = 16/32 (50%), Positives = 19/32 (59%), Gaps = 1/32 (3%)
 Frame = +3

Query: 2910 QFLCS-SGRCVAEALLCNGQDDCGDGSDERGC 2940
            QF C  SG C+  A  C+ + DC DGSDE  C
Sbjct: 333  QFTCQDSGLCIDLARRCDRRRDCEDGSDEERC 428

 Score = 62.4 bits (150), Expect = 4e-09,   Method: Compositional matrix adjust.
 Identities = 47/114 (41%), Positives = 63/114 (55%)
 Frame = +1

Query: 3619 FQCKSGHCIPLRWRCDADADCMDGSDEEACGTGVRTCPLDEFQCNNTLCKPLAWKCDGED 3678
            F+C+ G CI  R RCD   DC D SDE  C      C  D+F C + LC    ++C+G  
Sbjct: 4    FECEDGSCIDNRLRCDGVPDCSDRSDESNC-----PCRDDQFSCRDGLCIEAEFRCNGRV 168

Query: 3679 DCGDNSDENPEECARFICPPNRPFRCKNDRVCLWIGRQCDGVDNCGDGTDEEDC 3732
            +C D SDE  EEC R  C     F C +D  C+ +  QC+ V +C DG+DE++C
Sbjct: 169  ECEDGSDE--EECPRRTCSF-AEFTC-DDGQCVDLRDQCNQVTDCQDGSDEKNC 318

 Score = 55.5 bits (132), Expect = 5e-07,   Method: Compositional matrix adjust.
 Identities = 42/118 (35%), Positives = 60/118 (50%)
 Frame = +1

Query: 2823 EFMCQNRLCIPKHFVCDHDRDCADGSDESPECEYPTCGPNEFRCANGRCLSSRQWECDGE 2882
            +F C++  CI     CD   DC+D SDES       C  ++F C +G C+ + ++ C+G 
Sbjct: 1    DFECEDGSCIDNRLRCDGVPDCSDRSDES----NCPCRDDQFSCRDGLCIEA-EFRCNGR 165

Query: 2883 NDCHDHSDEAPKNPHCTSPEHKCNASSQFLCSSGRCVAEALLCNGQDDCGDGSDERGC 2940
             +C D SDE         P   C + ++F C  G+CV     CN   DC DGSDE+ C
Sbjct: 166  VECEDGSDEE------ECPRRTC-SFAEFTCDDGQCVDLRDQCNQVTDCQDGSDEKNC 318

 Score = 54.7 bits (130), Expect = 9e-07,   Method: Compositional matrix adjust.
 Identities = 42/116 (36%), Positives = 52/116 (44%)
 Frame = +1

Query: 983  FTCNNGRCININWRXXXXXXXXXXXXEAGCSHSCSSTQFKCNSGRCIPEHWTCDGDNDCG 1042
            F C +G CI+   R            E+ C   C   QF C  G CI   + C+G  +C 
Sbjct: 4    FECEDGSCIDNRLRCDGVPDCSDRSDESNCP--CRDDQFSCRDGLCIEAEFRCNGRVECE 177

Query: 1043 DYSDETHANCTNQATRPPGGCHSDEFQCRLDGLCIPLRWRCDGDTDCMDSSDEKSC 1098
            D SDE           P   C   EF C  DG C+ LR +C+  TDC D SDEK+C
Sbjct: 178  DGSDEEEC--------PRRTCSFAEFTCD-DGQCVDLRDQCNQVTDCQDGSDEKNC 318

 Score = 53.9 bits (128), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 34/98 (34%), Positives = 49/98 (50%)
 Frame = +1

Query: 859 EFACANNRCIQERWKCDGDNDCLDNSDEAPALCHQHTCPSDRFKCENNRCIPNRWLCDGD 918
           +F C +  CI  R +CDG  DC D SDE+   C       D+F C +  CI   + C+G 
Sbjct: 1   DFECEDGSCIDNRLRCDGVPDCSDRSDESNCPCR-----DDQFSCRDGLCIEAEFRCNGR 165

Query: 919 NDCGNSEDESNATCSARTCPPNQFSCASGRCIPISWTC 956
            +C +  DE    C  RTC   +F+C  G+C+ +   C
Sbjct: 166 VECEDGSDEEE--CPRRTCSFAEFTCDDGQCVDLRDQC 273

 Score = 46.6 bits (109), Expect(2) = 2e-06,   Method: Compositional matrix adjust.
 Identities = 31/63 (49%), Positives = 36/63 (57%)
 Frame = +2

Query: 3624 GHCIPLRWRCDADADCMDGSDEEACGTGVRTCPLDEFQCNNTLCKPLAWKCDGEDDCGDN 3683
            G CIP   +CD   DC DGSDEE C  GV  C  +EF+CN+  C     KCD   +C D 
Sbjct: 461  GRCIPDSRKCDRRRDCADGSDEEEC-EGV--CGRNEFRCNDGTCVERRVKCDRFVNCPDG 631

Query: 3684 SDE 3686
            SDE
Sbjct: 632  SDE 640

 Score = 26.2 bits (56), Expect(2) = 2e-06,   Method: Composition-based stats.
 Identities = 19/47 (40%), Positives = 28/47 (59%), Gaps = 1/47 (2%)
 Frame = +3

Query: 3576 CSESEFSCAN-GRCIAGRWKCDGDHDCADGSDEKDCTPRCDMDQFQC 3621
            C + +F+C + G CI    +CD   DC DGSDE+ C   C  ++F+C
Sbjct: 321  CRDDQFTCQDSGLCIDLARRCDRRRDCEDGSDEERCP--CLANEFRC 455

 Score = 48.9 bits (115), Expect(2) = 2e-06,   Method: Compositional matrix adjust.
 Identities = 34/80 (42%), Positives = 42/80 (52%)
 Frame = +1

Query: 2522 NSSCRAQDEFECANGECISFSLTCDGVSHCKDKSDEKPSYCNSRRCKKTFRQCNNGRCVS 2581
            N  CR  D+F C +G CI     C+G   C+D SDE+   C  R C      C++G+CV 
Sbjct: 88   NCPCR-DDQFSCRDGLCIEAEFRCNGRVECEDGSDEEE--CPRRTCSFAEFTCDDGQCVD 258

Query: 2582 NMLWCNGVDDCGDGSDEIPC 2601
                CN V DC DGSDE  C
Sbjct: 259  LRDQCNQVTDCQDGSDEKNC 318

 Score = 23.9 bits (50), Expect(2) = 2e-06,   Method: Composition-based stats.
 Identities = 20/49 (40%), Positives = 28/49 (57%), Gaps = 1/49 (2%)
 Frame = +3

Query: 2605 ACGVGEFRCRD-GSCIGNSSRCNQFVDCEDASDEMNCSTTDCSSYFRLG 2652
            +C   +F C+D G CI  + RC++  DCED SDE  C     ++ FR G
Sbjct: 318  SCRDDQFTCQDSGLCIDLARRCDRRRDCEDGSDEERCPCL--ANEFRCG 458

 Score = 48.1 bits (113), Expect = 8e-05,   Method: Compositional matrix adjust.
 Identities = 34/78 (43%), Positives = 45/78 (57%)
 Frame = +1

Query: 28  CSPKQFACRDQITCISKGWRCDGERDCPDGSDEAPEICPQSKAQRCPPNEHSCLGTELCV 87
           C   QF+CRD + CI   +RC+G  +C DGSDE  E CP+   + C   E +C   + CV
Sbjct: 97  CRDDQFSCRDGL-CIEAEFRCNGRVECEDGSDE--EECPR---RTCSFAEFTCDDGQ-CV 255

Query: 88  PMSRLCNGIQDCMDGSDE 105
            +   CN + DC DGSDE
Sbjct: 256 DLRDQCNQVTDCQDGSDE 309

 Score = 44.7 bits (104), Expect = 8e-04,   Method: Compositional matrix adjust.
 Identities = 30/73 (41%), Positives = 36/73 (49%)
 Frame = +2

Query: 1026 GRCIPEHWTCDGDNDCGDYSDETHANCTNQATRPPGGCHSDEFQCRLDGLCIPLRWRCDG 1085
            GRCIP+   CD   DC D SDE             G C  +EF+C  DG C+  R +CD 
Sbjct: 461  GRCIPDSRKCDRRRDCADGSDEEEC---------EGVCGRNEFRCN-DGTCVERRVKCDR 610

Query: 1086 DTDCMDSSDEKSC 1098
              +C D SDE  C
Sbjct: 611  FVNCPDGSDEFDC 649

 Score = 44.7 bits (104), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 31/97 (31%), Positives = 49/97 (50%)
 Frame = +1

Query: 833 DQVLDTDGVTCLANPSYVPPPQCQPGEFACANNRCIQERWKCDGDNDCLDNSDEAPALCH 892
           D  L  DGV   ++ S      C+  +F+C +  CI+  ++C+G  +C D SDE    C 
Sbjct: 31  DNRLRCDGVPDCSDRSDESNCPCRDDQFSCRDGLCIEAEFRCNGRVECEDGSDEEE--CP 204

Query: 893 QHTCPSDRFKCENNRCIPNRWLCDGDNDCGNSEDESN 929
           + TC    F C++ +C+  R  C+   DC +  DE N
Sbjct: 205 RRTCSFAEFTCDDGQCVDLRDQCNQVTDCQDGSDEKN 315

 Score = 42.0 bits (97), Expect(2) = 0.001,   Method: Compositional matrix adjust.
 Identities = 18/45 (40%), Positives = 25/45 (55%)
 Frame = +2

Query: 2707 GRCIPMSWTCDKEDDCENGEDETHCNKFCSEAQFECQNHRCISKQ 2751
            GRCIP S  CD+  DC +G DE  C   C   +F C +  C+ ++
Sbjct: 461  GRCIPDSRKCDRRRDCADGSDEEECEGVCGRNEFRCNDGTCVERR 595

 Score = 21.2 bits (43), Expect(2) = 0.001,   Method: Composition-based stats.
 Identities = 17/44 (38%), Positives = 20/44 (45%)
 Frame = +3

Query: 2661 CERTSLCYAPSWVCDGANDCGDYSDERDCPGVKRPRCPLNYFAC 2704
            C+ + LC   +  CD   DC D SDE  CP      C  N F C
Sbjct: 342  CQDSGLCIDLARRCDRRRDCEDGSDEERCP------CLANEFRC 455

 Score = 42.0 bits (97), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 24/63 (38%), Positives = 32/63 (50%)
 Frame = +2

Query: 2788 CVPERWLCDGDKDCTDGADESVTAGCLYNSTCDDREFMCQNRLCIPKHFVCDHDRDCADG 2847
            C+P+   CD  +DC DG+DE    G      C   EF C +  C+ +   CD   +C DG
Sbjct: 467  CIPDSRKCDRRRDCADGSDEEECEG-----VCGRNEFRCNDGTCVERRVKCDRFVNCPDG 631

Query: 2848 SDE 2850
            SDE
Sbjct: 632  SDE 640

 Score = 41.2 bits (95), Expect = 0.010,   Method: Compositional matrix adjust.
 Identities = 25/49 (51%), Positives = 28/49 (57%)
 Frame = +2

Query: 3466 RCIPRVWVCDRDNDCVDGSDEPANCTQMTCGVDEFRCKDSGRCIPARWK 3514
            RCIP    CDR  DC DGSDE     +  CG +EFRC D G C+  R K
Sbjct: 464  RCIPDSRKCDRRRDCADGSDEEE--CEGVCGRNEFRCND-GTCVERRVK 601

 Score = 39.3 bits (90), Expect = 0.041,   Method: Compositional matrix adjust.
 Identities = 26/64 (40%), Positives = 32/64 (50%)
 Frame = +2

Query: 3346 KCIPFWWKCDTEDDCGDHSDEPPDCPEFKCRPGQFQCSTGICTNPAFICDGDNDCQDNSD 3405
            +CIP   KCD   DC D SDE     E  C   +F+C+ G C      CD   +C D SD
Sbjct: 464  RCIPDSRKCDRRRDCADGSDEEE--CEGVCGRNEFRCNDGTCVERRVKCDRFVNCPDGSD 637

Query: 3406 EANC 3409
            E +C
Sbjct: 638  EFDC 649

 Score = 35.0 bits (79), Expect(2) = 0.057,   Method: Compositional matrix adjust.
 Identities = 26/65 (40%), Positives = 34/65 (52%)
 Frame = +2

Query: 3385 GICTNPAFICDGDNDCQDNSDEANCDIHVCLPSQFKCTNTNRCIPGIFRCNGQDNCGDGE 3444
            G C   +  CD   DC D SDE  C+  VC  ++F+C N   C+    +C+   NC DG 
Sbjct: 461  GRCIPDSRKCDRRRDCADGSDEEECE-GVCGRNEFRC-NDGTCVERRVKCDRFVNCPDGS 634

Query: 3445 DERDC 3449
            DE DC
Sbjct: 635  DEFDC 649

 Score = 22.3 bits (46), Expect(2) = 0.057,   Method: Composition-based stats.
 Identities = 20/52 (38%), Positives = 26/52 (50%), Gaps = 1/52 (1%)
 Frame = +3

Query: 3334 NCTASQFVCKNDK-CIPFWWKCDTEDDCGDHSDEPPDCPEFKCRPGQFQCST 3384
            +C   QF C++   CI    +CD   DC D SDE   CP   C   +F+C T
Sbjct: 318  SCRDDQFTCQDSGLCIDLARRCDRRRDCEDGSDE-ERCP---CLANEFRCGT 461

 Score = 37.4 bits (85), Expect = 0.12,   Method: Compositional matrix adjust.
 Identities = 31/73 (42%), Positives = 37/73 (50%)
 Frame = +1

Query: 33  FACRDQITCISKGWRCDGERDCPDGSDEAPEICPQSKAQRCPPNEHSCLGTELCVPMSRL 92
           F C D  +CI    RCDG  DC D SDE+   CP      C  ++ SC    LC+     
Sbjct: 4   FECEDG-SCIDNRLRCDGVPDCSDRSDESN--CP------CRDDQFSCRDG-LCIEAEFR 153

Query: 93  CNGIQDCMDGSDE 105
           CNG  +C DGSDE
Sbjct: 154 CNGRVECEDGSDE 192

 Score = 37.0 bits (84), Expect = 0.18,   Method: Compositional matrix adjust.
 Identities = 34/107 (31%), Positives = 51/107 (47%), Gaps = 1/107 (0%)
 Frame = +1

Query: 3659 EFQCNNTLCKPLAWKCDGEDDCGDNSDENPEECARFICP-PNRPFRCKNDRVCLWIGRQC 3717
            +F+C +  C     +CDG  DC D SDE+        CP  +  F C+ D +C+    +C
Sbjct: 1    DFECEDGSCIDNRLRCDGVPDCSDRSDESN-------CPCRDDQFSCR-DGLCIEAEFRC 156

Query: 3718 DGVDNCGDGTDEEDCEPPTAQNPHCKDKKEFLCRNQRCLSSSLRCNM 3764
            +G   C DG+DEE+C   T          EF C + +C+    +CN 
Sbjct: 157  NGRVECEDGSDEEECPRRTCS------FAEFTCDDGQCVDLRDQCNQ 279

 Score = 36.6 bits (83), Expect = 0.26,   Method: Compositional matrix adjust.
 Identities = 25/67 (37%), Positives = 33/67 (49%)
 Frame = +2

Query: 2535 NGECISFSLTCDGVSHCKDKSDEKPSYCNSRRCKKTFRQCNNGRCVSNMLWCNGVDDCGD 2594
            +G CI  S  CD    C D SDE+        C +   +CN+G CV   + C+   +C D
Sbjct: 458  DGRCIPDSRKCDRRRDCADGSDEEEC---EGVCGRNEFRCNDGTCVERRVKCDRFVNCPD 628

Query: 2595 GSDEIPC 2601
            GSDE  C
Sbjct: 629  GSDEFDC 649

 Score = 35.4 bits (80), Expect = 0.57,   Method: Compositional matrix adjust.
 Identities = 23/70 (32%), Positives = 34/70 (48%)
 Frame = +2

Query: 864 NNRCIQERWKCDGDNDCLDNSDEAPALCHQHTCPSDRFKCENNRCIPNRWLCDGDNDCGN 923
           + RCI +  KCD   DC D SDE      +  C  + F+C +  C+  R  CD   +C +
Sbjct: 458 DGRCIPDSRKCDRRRDCADGSDEEEC---EGVCGRNEFRCNDGTCVERRVKCDRFVNCPD 628

Query: 924 SEDESNATCS 933
             DE +  C+
Sbjct: 629 GSDEFDCACN 658

 Score = 35.0 bits (79), Expect = 0.72,   Method: Compositional matrix adjust.
 Identities = 33/111 (29%), Positives = 48/111 (43%)
 Frame = +1

Query: 2740 FECQNHRCISKQWLXXXXXXXXXXXXEAAHCEGKTCGPSSFSCPGTHVCVPERWLCDGDK 2799
            FEC++  CI  + L            + ++C    C    FSC    +C+   + C+G  
Sbjct: 4    FECEDGSCIDNR-LRCDGVPDCSDRSDESNC---PCRDDQFSCR-DGLCIEAEFRCNGRV 168

Query: 2800 DCTDGADESVTAGCLYNSTCDDREFMCQNRLCIPKHFVCDHDRDCADGSDE 2850
            +C DG+DE          TC   EF C +  C+     C+   DC DGSDE
Sbjct: 169  ECEDGSDEEECP----RRTCSFAEFTCDDGQCVDLRDQCNQVTDCQDGSDE 309

 Score = 30.4 bits (67), Expect(2) = 0.74,   Method: Compositional matrix adjust.
 Identities = 25/75 (33%), Positives = 31/75 (41%)
 Frame = +2

Query: 2615 DGSCIGNSSRCNQFVDCEDASDEMNCSTTDCSSYFRLGVKGVLFQPCERTSLCYAPSWVC 2674
            DG CI +S +C++  DC D SDE  C      + FR                C      C
Sbjct: 458  DGRCIPDSRKCDRRRDCADGSDEEECEGVCGRNEFRCN-----------DGTCVERRVKC 604

Query: 2675 DGANDCGDYSDERDC 2689
            D   +C D SDE DC
Sbjct: 605  DRFVNCPDGSDEFDC 649

 Score = 23.1 bits (48), Expect(2) = 0.74,   Method: Composition-based stats.
 Identities = 11/20 (55%), Positives = 11/20 (55%)
 Frame = +3

Query: 2594 DGSDEIPCNKTACGVGEFRC 2613
            DGSDE  C    C   EFRC
Sbjct: 405  DGSDEERC---PCLANEFRC 455

 Score = 33.9 bits (76), Expect = 1.7,   Method: Composition-based stats.
 Identities = 22/62 (35%), Positives = 30/62 (48%)
 Frame = +3

Query: 3414 CLPSQFKCTNTNRCIPGIFRCNGQDNCGDGEDERDCPEVTCAPNQFQCSITKRCIPRVWV 3473
            C   QF C ++  CI    RC+ + +C DG DE  CP   C  N+F+C      + R  V
Sbjct: 321  CRDDQFTCQDSGLCIDLARRCDRRRDCEDGSDEERCP---CLANEFRCGTVAAFLIRASV 491

Query: 3474 CD 3475
             D
Sbjct: 492  TD 497

 Score = 32.3 bits (72), Expect(2) = 2.2,   Method: Compositional matrix adjust.
 Identities = 20/67 (29%), Positives = 27/67 (40%)
 Frame = +2

Query: 987  NGRCININWRXXXXXXXXXXXXEAGCSHSCSSTQFKCNSGRCIPEHWTCDGDNDCGDYSD 1046
            +GRCI  + +            E  C   C   +F+CN G C+     CD   +C D SD
Sbjct: 458  DGRCIPDSRKCDRRRDCADGSDEEECEGVCGRNEFRCNDGTCVERRVKCDRFVNCPDGSD 637

Query: 1047 ETHANCT 1053
            E    C 
Sbjct: 638  EFDCACN 658

 Score = 19.6 bits (39), Expect(2) = 2.2,   Method: Composition-based stats.
 Identities = 17/53 (32%), Positives = 25/53 (47%), Gaps = 1/53 (1%)
 Frame = +3

Query: 895 TCPSDRFKCENN-RCIPNRWLCDGDNDCGNSEDESNATCSARTCPPNQFSCAS 946
           +C  D+F C+++  CI     CD   DC +  DE    C A     N+F C +
Sbjct: 318 SCRDDQFTCQDSGLCIDLARRCDRRRDCEDGSDEERCPCLA-----NEFRCGT 461

 Score = 31.2 bits (69), Expect = 9.4,   Method: Composition-based stats.
 Identities = 27/65 (41%), Positives = 33/65 (50%)
 Frame = +3

Query: 1063 CHSDEFQCRLDGLCIPLRWRCDGDTDCMDSSDEKSCEGVTHVCDPNVKFGCKDSARCISK 1122
            C  D+F C+  GLCI L  RCD   DC D SDE+ C      C  N +F C   A  + +
Sbjct: 321  CRDDQFTCQDSGLCIDLARRCDRRRDCEDGSDEERCP-----CLAN-EFRCGTVAAFLIR 482

Query: 1123 AWVCD 1127
            A V D
Sbjct: 483  ASVTD 497

 Score = 31.2 bits (69), Expect = 9.6,   Method: Compositional matrix adjust.
 Identities = 25/65 (38%), Positives = 29/65 (44%)
 Frame = +2

Query: 41  CISKGWRCDGERDCPDGSDEAPEICPQSKAQRCPPNEHSCLGTELCVPMSRLCNGIQDCM 100
           CI    +CD  RDC DGSDE      +     C  NE  C     CV     C+   +C 
Sbjct: 467 CIPDSRKCDRRRDCADGSDE------EECEGVCGRNEFRC-NDGTCVERRVKCDRFVNCP 625

Query: 101 DGSDE 105
           DGSDE
Sbjct: 626 DGSDE 640
>30369
          Length = 348

 Score = 55.8 bits (133), Expect(2) = 9e-13,   Method: Compositional matrix adjust.
 Identities = 32/72 (44%), Positives = 45/72 (62%), Gaps = 1/72 (1%)
 Frame = -3

Query: 3542 FRCKNNR-CVPGRWQCDYDNDCGDNSDEESCTPRPCSESEFSCANGRCIAGRWKCDGDHD 3600
             RC+ +  C+    +CD   DC D SDEE CT   CS+ +F+C +G+C+  R +CDG  D
Sbjct: 337  LRCRTSGICINRPLRCDGKPDCQDASDEEYCTG--CSDDQFTCLSGQCVERRNRCDGHVD 164

Query: 3601 CADGSDEKDCTP 3612
            C DG+DE +C P
Sbjct: 163  CVDGTDEYNCXP 128

 Score = 38.9 bits (89), Expect(2) = 9e-13,   Method: Compositional matrix adjust.
 Identities = 18/35 (51%), Positives = 22/35 (62%)
 Frame = -1

Query: 3614 CDMDQFQCKSGHCIPLRWRCDADADCMDGSDEEAC 3648
            C  DQ++C SG+CI    RCD+ ADC  G DE  C
Sbjct: 120  CSPDQYRCISGNCISYAQRCDSRADCPSGDDEFNC 16

 Score = 59.3 bits (142), Expect(2) = 4e-10,   Method: Compositional matrix adjust.
 Identities = 33/65 (50%), Positives = 39/65 (60%)
 Frame = -3

Query: 3584 ANGRCIAGRWKCDGDHDCADGSDEKDCTPRCDMDQFQCKSGHCIPLRWRCDADADCMDGS 3643
             +G CI    +CDG  DC D SDE+ CT  C  DQF C SG C+  R RCD   DC+DG+
Sbjct: 325  TSGICINRPLRCDGKPDCQDASDEEYCTG-CSDDQFTCLSGQCVERRNRCDGHVDCVDGT 149

Query: 3644 DEEAC 3648
            DE  C
Sbjct: 148  DEYNC 134

 Score = 25.8 bits (55), Expect(2) = 4e-10,   Method: Compositional matrix adjust.
 Identities = 12/33 (36%), Positives = 17/33 (51%)
 Frame = -1

Query: 3654 TCPLDEFQCNNTLCKPLAWKCDGEDDCGDNSDE 3686
            TC  D+++C +  C   A +CD   DC    DE
Sbjct: 123  TCSPDQYRCISGNCISYAQRCDSRADCPSGDDE 25

 Score = 44.7 bits (104), Expect(2) = 4e-08,   Method: Compositional matrix adjust.
 Identities = 29/67 (43%), Positives = 37/67 (55%)
 Frame = -3

Query: 3383 STGICTNPAFICDGDNDCQDNSDEANCDIHVCLPSQFKCTNTNRCIPGIFRCNGQDNCGD 3442
            ++GIC N    CDG  DCQD SDE  C    C   QF C  + +C+    RC+G  +C D
Sbjct: 325  TSGICINRPLRCDGKPDCQDASDEEYC--TGCSDDQFTCL-SGQCVERRNRCDGHVDCVD 155

Query: 3443 GEDERDC 3449
            G DE +C
Sbjct: 154  GTDEYNC 134

 Score = 33.9 bits (76), Expect(2) = 4e-08,   Method: Compositional matrix adjust.
 Identities = 17/37 (45%), Positives = 22/37 (59%)
 Frame = -1

Query: 3450 PEVTCAPNQFQCSITKRCIPRVWVCDRDNDCVDGSDE 3486
            P VTC+P+Q++C I+  CI     CD   DC  G DE
Sbjct: 132  PPVTCSPDQYRC-ISGNCISYAQRCDSRADCPSGDDE 25

 Score = 40.0 bits (92), Expect(2) = 1e-07,   Method: Compositional matrix adjust.
 Identities = 28/68 (41%), Positives = 36/68 (52%)
 Frame = -3

Query: 2534 ANGECISFSLTCDGVSHCKDKSDEKPSYCNSRRCKKTFRQCNNGRCVSNMLWCNGVDDCG 2593
             +G CI+  L CDG   C+D SDE+  YC    C      C +G+CV     C+G  DC 
Sbjct: 325  TSGICINRPLRCDGKPDCQDASDEE--YCTG--CSDDQFTCLSGQCVERRNRCDGHVDCV 158

Query: 2594 DGSDEIPC 2601
            DG+DE  C
Sbjct: 157  DGTDEYNC 134

 Score = 37.0 bits (84), Expect(2) = 1e-07,   Method: Compositional matrix adjust.
 Identities = 15/40 (37%), Positives = 21/40 (52%)
 Frame = -1

Query: 2606 CGVGEFRCRDGSCIGNSSRCNQFVDCEDASDEMNCSTTDC 2645
            C   ++RC  G+CI  + RC+   DC    DE NC   +C
Sbjct: 120  CSPDQYRCISGNCISYAQRCDSRADCPSGDDEFNCPAREC 1

 Score = 42.7 bits (99), Expect(2) = 1e-07,   Method: Compositional matrix adjust.
 Identities = 24/72 (33%), Positives = 35/72 (48%)
 Frame = -3

Query: 2779 SFSCPGTHVCVPERWLCDGDKDCTDGADESVTAGCLYNSTCDDREFMCQNRLCIPKHFVC 2838
            +  C  + +C+     CDG  DC D +DE       Y + C D +F C +  C+ +   C
Sbjct: 340  ALRCRTSGICINRPLRCDGKPDCQDASDEE------YCTGCSDDQFTCLSGQCVERRNRC 179

Query: 2839 DHDRDCADGSDE 2850
            D   DC DG+DE
Sbjct: 178  DGHVDCVDGTDE 143

 Score = 34.3 bits (77), Expect(2) = 1e-07,   Method: Compositional matrix adjust.
 Identities = 15/34 (44%), Positives = 20/34 (58%)
 Frame = -1

Query: 2858 TCGPNEFRCANGRCLSSRQWECDGENDCHDHSDE 2891
            TC P+++RC +G C+S  Q  CD   DC    DE
Sbjct: 123  TCSPDQYRCISGNCISYAQ-RCDSRADCPSGDDE 25

 Score = 40.4 bits (93), Expect(2) = 5e-07,   Method: Compositional matrix adjust.
 Identities = 28/68 (41%), Positives = 37/68 (54%), Gaps = 1/68 (1%)
 Frame = -3

Query: 2830 LCIPKHFVCDHDRDCADGSDESPECEYPT-CGPNEFRCANGRCLSSRQWECDGENDCHDH 2888
            +CI +   CD   DC D SDE    EY T C  ++F C +G+C+  R+  CDG  DC D 
Sbjct: 316  ICINRPLRCDGKPDCQDASDE----EYCTGCSDDQFTCLSGQCV-ERRNRCDGHVDCVDG 152

Query: 2889 SDEAPKNP 2896
            +DE    P
Sbjct: 151  TDEYNCXP 128

 Score = 34.7 bits (78), Expect(2) = 5e-07,   Method: Compositional matrix adjust.
 Identities = 18/47 (38%), Positives = 24/47 (51%)
 Frame = -1

Query: 2899 TSPEHKCNASSQFLCSSGRCVAEALLCNGQDDCGDGSDERGCHVNEC 2945
            T P   C+   Q+ C SG C++ A  C+ + DC  G DE  C   EC
Sbjct: 138  TVPPVTCS-PDQYRCISGNCISYAQRCDSRADCPSGDDEFNCPAREC 1

 Score = 37.7 bits (86), Expect(2) = 7e-06,   Method: Compositional matrix adjust.
 Identities = 27/65 (41%), Positives = 32/65 (49%), Gaps = 2/65 (3%)
 Frame = -3

Query: 3347 CIPFWWKCDTEDDCGDHSDEPPDCPEF--KCRPGQFQCSTGICTNPAFICDGDNDCQDNS 3404
            CI    +CD + DC D SDE     E+   C   QF C +G C      CDG  DC D +
Sbjct: 313  CINRPLRCDGKPDCQDASDE-----EYCTGCSDDQFTCLSGQCVERRNRCDGHVDCVDGT 149

Query: 3405 DEANC 3409
            DE NC
Sbjct: 148  DEYNC 134

 Score = 33.5 bits (75), Expect(2) = 7e-06,   Method: Compositional matrix adjust.
 Identities = 16/41 (39%), Positives = 24/41 (58%)
 Frame = -1

Query: 3414 CLPSQFKCTNTNRCIPGIFRCNGQDNCGDGEDERDCPEVTC 3454
            C P Q++C + N CI    RC+ + +C  G+DE +CP   C
Sbjct: 120  CSPDQYRCISGN-CISYAQRCDSRADCPSGDDEFNCPAREC 1

 Score = 50.1 bits (118), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 32/74 (43%), Positives = 38/74 (51%)
 Frame = -3

Query: 1025 SGRCIPEHWTCDGDNDCGDYSDETHANCTNQATRPPGGCHSDEFQCRLDGLCIPLRWRCD 1084
            SG CI     CDG  DC D SDE +            GC  D+F C L G C+  R RCD
Sbjct: 322  SGICINRPLRCDGKPDCQDASDEEYCT----------GCSDDQFTC-LSGQCVERRNRCD 176

Query: 1085 GDTDCMDSSDEKSC 1098
            G  DC+D +DE +C
Sbjct: 175  GHVDCVDGTDEYNC 134

 Score = 48.9 bits (115), Expect(2) = 3e-05,   Method: Compositional matrix adjust.
 Identities = 28/65 (43%), Positives = 37/65 (56%)
 Frame = -3

Query: 2576 NGRCVSNMLWCNGVDDCGDGSDEIPCNKTACGVGEFRCRDGSCIGNSSRCNQFVDCEDAS 2635
            +G C++  L C+G  DC D SDE  C  T C   +F C  G C+   +RC+  VDC D +
Sbjct: 322  SGICINRPLRCDGKPDCQDASDEEYC--TGCSDDQFTCLSGQCVERRNRCDGHVDCVDGT 149

Query: 2636 DEMNC 2640
            DE NC
Sbjct: 148  DEYNC 134

 Score = 20.0 bits (40), Expect(2) = 3e-05,   Method: Compositional matrix adjust.
 Identities = 8/18 (44%), Positives = 9/18 (50%)
 Frame = -1

Query: 2674 CDGANDCGDYSDERDCPG 2691
            CD   DC    DE +CP 
Sbjct: 63   CDSRADCPSGDDEFNCPA 10

 Score = 36.2 bits (82), Expect(2) = 2e-04,   Method: Compositional matrix adjust.
 Identities = 16/41 (39%), Positives = 22/41 (53%)
 Frame = -1

Query: 3573 PRPCSESEFSCANGRCIAGRWKCDGDHDCADGSDEKDCTPR 3613
            P  CS  ++ C +G CI+   +CD   DC  G DE +C  R
Sbjct: 129  PVTCSPDQYRCISGNCISYAQRCDSRADCPSGDDEFNCPAR 7

 Score = 30.0 bits (66), Expect(2) = 2e-04,   Method: Compositional matrix adjust.
 Identities = 16/37 (43%), Positives = 21/37 (56%)
 Frame = -3

Query: 3537 CEPYQFRCKNNRCVPGRWQCDYDNDCGDNSDEESCTP 3573
            C   QF C + +CV  R +CD   DC D +DE +C P
Sbjct: 238  CSDDQFTCLSGQCVERRNRCDGHVDCVDGTDEYNCXP 128

 Score = 40.4 bits (93), Expect(2) = 2e-04,   Method: Compositional matrix adjust.
 Identities = 25/63 (39%), Positives = 32/63 (50%)
 Frame = -3

Query: 867 CIQERWKCDGDNDCLDNSDEAPALCHQHTCPSDRFKCENNRCIPNRWLCDGDNDCGNSED 926
           CI    +CDG  DC D SDE     +   C  D+F C + +C+  R  CDG  DC +  D
Sbjct: 313 CINRPLRCDGKPDCQDASDEE----YCTGCSDDQFTCLSGQCVERRNRCDGHVDCVDGTD 146

Query: 927 ESN 929
           E N
Sbjct: 145 EYN 137

 Score = 25.4 bits (54), Expect(2) = 2e-04,   Method: Compositional matrix adjust.
 Identities = 12/28 (42%), Positives = 15/28 (53%)
 Frame = -1

Query: 929 NATCSARTCPPNQFSCASGRCIPISWTC 956
           N T    TC P+Q+ C SG CI  +  C
Sbjct: 144 NTTVPPVTCSPDQYRCISGNCISYAQRC 61

 Score = 33.1 bits (74), Expect(2) = 4e-04,   Method: Compositional matrix adjust.
 Identities = 13/32 (40%), Positives = 21/32 (65%)
 Frame = -3

Query: 855 CQPGEFACANNRCIQERWKCDGDNDCLDNSDE 886
           C   +F C + +C++ R +CDG  DC+D +DE
Sbjct: 238 CSDDQFTCLSGQCVERRNRCDGHVDCVDGTDE 143

 Score = 32.0 bits (71), Expect(2) = 4e-04,   Method: Compositional matrix adjust.
 Identities = 17/43 (39%), Positives = 23/43 (53%)
 Frame = -1

Query: 895 TCPSDRFKCENNRCIPNRWLCDGDNDCGNSEDESNATCSARTC 937
           TC  D+++C +  CI     CD   DC + +DE N  C AR C
Sbjct: 123 TCSPDQYRCISGNCISYAQRCDSRADCPSGDDEFN--CPAREC 1

 Score = 44.7 bits (104), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 30/77 (38%), Positives = 37/77 (48%)
 Frame = -3

Query: 2864 FRCANGRCLSSRQWECDGENDCHDHSDEAPKNPHCTSPEHKCNASSQFLCSSGRCVAEAL 2923
             RC       +R   CDG+ DC D SDE     +CT       +  QF C SG+CV    
Sbjct: 337  LRCRTSGICINRPLRCDGKPDCQDASDEE----YCTG-----CSDDQFTCLSGQCVERRN 185

Query: 2924 LCNGQDDCGDGSDERGC 2940
             C+G  DC DG+DE  C
Sbjct: 184  RCDGHVDCVDGTDEYNC 134

 Score = 44.3 bits (103), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 30/64 (46%), Positives = 34/64 (53%)
 Frame = -3

Query: 3623 SGHCIPLRWRCDADADCMDGSDEEACGTGVRTCPLDEFQCNNTLCKPLAWKCDGEDDCGD 3682
            SG CI    RCD   DC D SDEE C TG   C  D+F C +  C     +CDG  DC D
Sbjct: 322  SGICINRPLRCDGKPDCQDASDEEYC-TG---CSDDQFTCLSGQCVERRNRCDGHVDCVD 155

Query: 3683 NSDE 3686
             +DE
Sbjct: 154  GTDE 143

 Score = 43.1 bits (100), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 27/71 (38%), Positives = 34/71 (47%)
 Frame = -3

Query: 2661 CERTSLCYAPSWVCDGANDCGDYSDERDCPGVKRPRCPLNYFACPSGRCIPMSWTCDKED 2720
            C  + +C      CDG  DC D SDE  C G     C  + F C SG+C+     CD   
Sbjct: 331  CRTSGICINRPLRCDGKPDCQDASDEEYCTG-----CSDDQFTCLSGQCVERRNRCDGHV 167

Query: 2721 DCENGEDETHC 2731
            DC +G DE +C
Sbjct: 166  DCVDGTDEYNC 134

 Score = 42.7 bits (99), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 26/68 (38%), Positives = 38/68 (55%)
 Frame = -3

Query: 3419 FKCTNTNRCIPGIFRCNGQDNCGDGEDERDCPEVTCAPNQFQCSITKRCIPRVWVCDRDN 3478
             +C  +  CI    RC+G+ +C D  DE  C    C+ +QF C ++ +C+ R   CD   
Sbjct: 337  LRCRTSGICINRPLRCDGKPDCQDASDEEYC--TGCSDDQFTC-LSGQCVERRNRCDGHV 167

Query: 3479 DCVDGSDE 3486
            DCVDG+DE
Sbjct: 166  DCVDGTDE 143

 Score = 42.4 bits (98), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 29/73 (39%), Positives = 39/73 (53%)
 Frame = -3

Query: 33  FACRDQITCISKGWRCDGERDCPDGSDEAPEICPQSKAQRCPPNEHSCLGTELCVPMSRL 92
             CR    CI++  RCDG+ DC D SDE  E C       C  ++ +CL  + CV     
Sbjct: 337 LRCRTSGICINRPLRCDGKPDCQDASDE--EYCTG-----CSDDQFTCLSGQ-CVERRNR 182

Query: 93  CNGIQDCMDGSDE 105
           C+G  DC+DG+DE
Sbjct: 181 CDGHVDCVDGTDE 143

 Score = 35.0 bits (79), Expect(2) = 0.005,   Method: Compositional matrix adjust.
 Identities = 17/44 (38%), Positives = 21/44 (47%)
 Frame = -1

Query: 3371 PEFKCRPGQFQCSTGICTNPAFICDGDNDCQDNSDEANCDIHVC 3414
            P   C P Q++C +G C + A  CD   DC    DE NC    C
Sbjct: 132  PPVTCSPDQYRCISGNCISYAQRCDSRADCPSGDDEFNCPAREC 1

 Score = 26.2 bits (56), Expect(2) = 0.005,   Method: Compositional matrix adjust.
 Identities = 12/34 (35%), Positives = 19/34 (55%)
 Frame = -3

Query: 3333 SNCTASQFVCKNDKCIPFWWKCDTEDDCGDHSDE 3366
            + C+  QF C + +C+    +CD   DC D +DE
Sbjct: 244  TGCSDDQFTCLSGQCVERRNRCDGHVDCVDGTDE 143

 Score = 31.2 bits (69), Expect(2) = 0.005,   Method: Compositional matrix adjust.
 Identities = 14/35 (40%), Positives = 20/35 (57%)
 Frame = -1

Query: 2697 CPLNYFACPSGRCIPMSWTCDKEDDCENGEDETHC 2731
            C  + + C SG CI  +  CD   DC +G+DE +C
Sbjct: 120  CSPDQYRCISGNCISYAQRCDSRADCPSGDDEFNC 16

 Score = 30.0 bits (66), Expect(2) = 0.005,   Method: Compositional matrix adjust.
 Identities = 30/80 (37%), Positives = 35/80 (43%), Gaps = 1/80 (1%)
 Frame = -3

Query: 2611 FRCR-DGSCIGNSSRCNQFVDCEDASDEMNCSTTDCSSYFRLGVKGVLFQPCERTSLCYA 2669
             RCR  G CI    RC+   DC+DASDE  C  T CS      + G           C  
Sbjct: 337  LRCRTSGICINRPLRCDGKPDCQDASDEEYC--TGCSDDQFTCLSG----------QCVE 194

Query: 2670 PSWVCDGANDCGDYSDERDC 2689
                CDG  DC D +DE +C
Sbjct: 193  RRNRCDGHVDCVDGTDEYNC 134

 Score = 40.8 bits (94), Expect = 0.011,   Method: Compositional matrix adjust.
 Identities = 24/61 (39%), Positives = 34/61 (55%)
 Frame = -3

Query: 1068 FQCRLDGLCIPLRWRCDGDTDCMDSSDEKSCEGVTHVCDPNVKFGCKDSARCISKAWVCD 1127
             +CR  G+CI    RCDG  DC D+SDE+ C G +     + +F C  S +C+ +   CD
Sbjct: 337  LRCRTSGICINRPLRCDGKPDCQDASDEEYCTGCS-----DDQFTCL-SGQCVERRNRCD 176

Query: 1128 G 1128
            G
Sbjct: 175  G 173

 Score = 40.0 bits (92), Expect = 0.022,   Method: Compositional matrix adjust.
 Identities = 33/97 (34%), Positives = 43/97 (44%)
 Frame = -3

Query: 987  NGRCININWRXXXXXXXXXXXXEAGCSHSCSSTQFKCNSGRCIPEHWTCDGDNDCGDYSD 1046
            +G CIN   R            E  C+  CS  QF C SG+C+     CDG  DC D +D
Sbjct: 322  SGICINRPLRCDGKPDCQDASDEEYCT-GCSDDQFTCLSGQCVERRNRCDGHVDCVDGTD 146

Query: 1047 ETHANCTNQATRPPGGCHSDEFQCRLDGLCIPLRWRC 1083
            E +   +N  +RP        +Q +L  LC  LR  C
Sbjct: 145  EYNCXPSNM*SRP-----VPLYQWKLHQLCPALRQSC 50

 Score = 38.5 bits (88), Expect = 0.062,   Method: Compositional matrix adjust.
 Identities = 19/36 (52%), Positives = 20/36 (55%)
 Frame = -1

Query: 25  PKTCSPKQFACRDQITCISKGWRCDGERDCPDGSDE 60
           P TCSP Q+ C     CIS   RCD   DCP G DE
Sbjct: 129 PVTCSPDQYRCISG-NCISYAQRCDSRADCPSGDDE 25

 Score = 33.1 bits (74), Expect(2) = 0.22,   Method: Compositional matrix adjust.
 Identities = 17/46 (36%), Positives = 27/46 (58%)
 Frame = -3

Query: 2706 SGRCIPMSWTCDKEDDCENGEDETHCNKFCSEAQFECQNHRCISKQ 2751
            SG CI     CD + DC++  DE +C   CS+ QF C + +C+ ++
Sbjct: 322  SGICINRPLRCDGKPDCQDASDEEYCTG-CSDDQFTCLSGQCVERR 188

 Score = 21.9 bits (45), Expect(2) = 0.22,   Method: Compositional matrix adjust.
 Identities = 12/34 (35%), Positives = 15/34 (44%)
 Frame = -1

Query: 2774 TCGPSSFSCPGTHVCVPERWLCDGDKDCTDGADE 2807
            TC P  + C   + C+     CD   DC  G DE
Sbjct: 123  TCSPDQYRCISGN-CISYAQRCDSRADCPSGDDE 25

 Score = 34.3 bits (77), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 16/41 (39%), Positives = 21/41 (51%)
 Frame = -1

Query: 3536 TCEPYQFRCKNNRCVPGRWQCDYDNDCGDNSDEESCTPRPC 3576
            TC P Q+RC +  C+    +CD   DC    DE +C  R C
Sbjct: 123  TCSPDQYRCISGNCISYAQRCDSRADCPSGDDEFNCPAREC 1

 Score = 33.9 bits (76), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 17/44 (38%), Positives = 22/44 (50%)
 Frame = -1

Query: 1057 TRPPGGCHSDEFQCRLDGLCIPLRWRCDGDTDCMDSSDEKSCEG 1100
            T PP  C  D+++C + G CI    RCD   DC    DE +C  
Sbjct: 138  TVPPVTCSPDQYRC-ISGNCISYAQRCDSRADCPSGDDEFNCPA 10

 Score = 27.3 bits (59), Expect(2) = 1.6,   Method: Compositional matrix adjust.
 Identities = 12/31 (38%), Positives = 18/31 (58%)
 Frame = -3

Query: 2527 AQDEFECANGECISFSLTCDGVSHCKDKSDE 2557
            + D+F C +G+C+     CDG   C D +DE
Sbjct: 235  SDDQFTCLSGQCVERRNRCDGHVDCVDGTDE 143

 Score = 25.0 bits (53), Expect(2) = 1.6,   Method: Compositional matrix adjust.
 Identities = 13/40 (32%), Positives = 17/40 (42%)
 Frame = -1

Query: 2567 CKKTFRQCNNGRCVSNMLWCNGVDDCGDGSDEIPCNKTAC 2606
            C     +C +G C+S    C+   DC  G DE  C    C
Sbjct: 120  CSPDQYRCISGNCISYAQRCDSRADCPSGDDEFNCPAREC 1

 Score = 33.1 bits (74), Expect = 2.8,   Method: Compositional matrix adjust.
 Identities = 14/37 (37%), Positives = 18/37 (48%)
 Frame = -1

Query: 850 VPPPQCQPGEFACANNRCIQERWKCDGDNDCLDNSDE 886
           VPP  C P ++ C +  CI    +CD   DC    DE
Sbjct: 135 VPPVTCSPDQYRCISGNCISYAQRCDSRADCPSGDDE 25
>34993
          Length = 626

 Score = 71.6 bits (174), Expect = 6e-12,   Method: Compositional matrix adjust.
 Identities = 52/142 (36%), Positives = 66/142 (46%), Gaps = 17/142 (11%)
 Frame = -2

Query: 65  CPQSKAQRCPPNEHSCLGTELCVPMSRLCNGIQDCMDGSDEGAHCR--------ELRANC 116
           C   K QR   +  +C+    C   +  C  +  C DG +   HCR        +   +C
Sbjct: 478 CECPKGQRLHVDARTCIAVSGCSVXNGGCEHV--CTDGYNGHFHCRCRPGYTLAQDGKSC 305

Query: 117 --------SRMGCQHHCVPTPSGPTCYCNSSFQLQADGKTCKDFDECSVY-GTCSQLCTN 167
                   S  GCQH CV       C C   ++L ADG++CKD DEC+   G C Q C N
Sbjct: 304 QEDNPCQHSNGGCQHTCVSDRGRAVCRCFQGYELAADGRSCKDIDECAKRNGDCLQRCVN 125

Query: 168 TDGSFTCGCVEGYLLQPDNRSC 189
           T GSFTC C +GY L  D RSC
Sbjct: 124 TQGSFTCTCTQGYQLGNDGRSC 59

 Score = 54.7 bits (130), Expect = 8e-07,   Method: Compositional matrix adjust.
 Identities = 31/72 (43%), Positives = 39/72 (54%), Gaps = 1/72 (1%)
 Frame = -2

Query: 2952 GCSQDCEDLKIGFKCRCRPGFRLKDDGRTCADLDECST-TFPCSQLCINTHGSYKCLCVE 3010
            GC   C   +    CRC  G+ L  DGR+C D+DEC+     C Q C+NT GS+ C C +
Sbjct: 271  GCQHTCVSDRGRAVCRCFQGYELAADGRSCKDIDECAKRNGDCLQRCVNTQGSFTCTCTQ 92

Query: 3011 GYAPRGGDPHSC 3022
            GY   G D  SC
Sbjct: 91   GYQ-LGNDGRSC 59

 Score = 49.3 bits (116), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 31/78 (39%), Positives = 41/78 (52%), Gaps = 1/78 (1%)
 Frame = -2

Query: 1186 CSLNNGGCSHNCSVAPGEGIVCSCPLGMELGSDNHTCQIQSYCAK-HLKCSQKCDQNKFS 1244
            C  +NGGC H C    G   VC C  G EL +D  +C+    CAK +  C Q+C   + S
Sbjct: 289  CQHSNGGCQHTCVSDRGR-AVCRCFQGYELAADGRSCKDIDECAKRNGDCLQRCVNTQGS 113

Query: 1245 VKCSCYEGWVLEPDGESC 1262
              C+C +G+ L  DG SC
Sbjct: 112  FTCTCTQGYQLGNDGRSC 59

 Score = 47.8 bits (112), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 27/82 (32%), Positives = 39/82 (47%), Gaps = 1/82 (1%)
 Frame = -2

Query: 1186 CSLNNGGCSHNCSVAPGEGIVCSCPLGMELGSDNHTCQIQSYCA-KHLKCSQKCDQNKFS 1244
            CS+ NGGC H C+        C C  G  L  D  +CQ  + C   +  C   C  ++  
Sbjct: 415  CSVXNGGCEHVCTDGYNGHFHCRCRPGYTLAQDGKSCQEDNPCQHSNGGCQHTCVSDRGR 236

Query: 1245 VKCSCYEGWVLEPDGESCRSLD 1266
              C C++G+ L  DG SC+ +D
Sbjct: 235  AVCRCFQGYELAADGRSCKDID 170

 Score = 46.6 bits (109), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 26/59 (44%), Positives = 32/59 (54%), Gaps = 1/59 (1%)
 Frame = -2

Query: 134 CYCNSSFQLQADGKTCKDFDECSVY-GTCSQLCTNTDGSFTCGCVEGYLLQPDNRSCKA 191
           C C+  F+L  D K+C D DEC  + G C   C NT G F C C +G  L  D R+C A
Sbjct: 601 CRCSMGFELAEDMKSCLDVDECVSHNGGCQHKCVNTYGGFNCECPKGQRLHVDARTCIA 425

 Score = 45.8 bits (107), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 29/81 (35%), Positives = 39/81 (48%), Gaps = 2/81 (2%)
 Frame = -2

Query: 120 GCQHHCVPTPSGP-TCYCNSSFQLQADGKTCKDFDECS-VYGTCSQLCTNTDGSFTCGCV 177
           GC+H C    +G   C C   + L  DGK+C++ + C    G C   C +  G   C C 
Sbjct: 397 GCEHVCTDGYNGHFHCRCRPGYTLAQDGKSCQEDNPCQHSNGGCQHTCVSDRGRAVCRCF 218

Query: 178 EGYLLQPDNRSCKAKNEPVDR 198
           +GY L  D RSCK  +E   R
Sbjct: 217 QGYELAADGRSCKDIDECAKR 155

 Score = 42.7 bits (99), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 31/85 (36%), Positives = 39/85 (45%), Gaps = 2/85 (2%)
 Frame = -2

Query: 1185 QCSLNNGGCSHNCSVAPGEGIVCSCPLGMELGSDNHTCQIQSYCA-KHLKCSQKC-DQNK 1242
            +C  +NGGC H C    G G  C CP G  L  D  TC   S C+  +  C   C D   
Sbjct: 541  ECVSHNGGCQHKCVNTYG-GFNCECPKGQRLHVDARTCIAVSGCSVXNGGCEHVCTDGYN 365

Query: 1243 FSVKCSCYEGWVLEPDGESCRSLDP 1267
                C C  G+ L  DG+SC+  +P
Sbjct: 364  GHFHCRCRPGYTLAQDGKSCQEDNP 290

 Score = 37.4 bits (85), Expect = 0.15,   Method: Compositional matrix adjust.
 Identities = 22/63 (34%), Positives = 30/63 (47%), Gaps = 1/63 (1%)
 Frame = -2

Query: 3794 GDEARCVRTEKAAYCACRSGFHTVPGQPGCQDINECL-RFGTCSQLCNNTKGGHLCSCAR 3852
            G +  CV     A C C  G+        C+DI+EC  R G C Q C NT+G   C+C +
Sbjct: 271  GCQHTCVSDRGRAVCRCFQGYELAADGRSCKDIDECAKRNGDCLQRCVNTQGSFTCTCTQ 92

Query: 3853 NFM 3855
             + 
Sbjct: 91   GYQ 83

 Score = 36.6 bits (83), Expect = 0.21,   Method: Compositional matrix adjust.
 Identities = 20/54 (37%), Positives = 28/54 (51%), Gaps = 7/54 (12%)
 Frame = -2

Query: 2480 LSPCRINNGGCQDLCLLTHQGHVNCSCRGGRIL-------QEDFTCRAVNSSCR 2526
            +S C + NGGC+ +C   + GH +C CR G  L       QED  C+  N  C+
Sbjct: 424  VSGCSVXNGGCEHVCTDGYNGHFHCRCRPGYTLAQDGKSCQEDNPCQHSNGGCQ 263

 Score = 33.9 bits (76), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 35/112 (31%), Positives = 47/112 (41%), Gaps = 14/112 (12%)
 Frame = -2

Query: 805 TNKCRVNNGGCSSLCLATPGSRQCACAEDQVLDTDGVTCLA-NPSYVPPPQCQP------ 857
            ++C  +NGGC   C+ T G   C C + Q L  D  TC+A +   V    C+       
Sbjct: 547 VDECVSHNGGCQHKCVNTYGGFNCECPKGQRLHVDARTCIAVSGCSVXNGGCEHVCTDGY 368

Query: 858 -GEFACANNRC------IQERWKCDGDNDCLDNSDEAPALCHQHTCPSDRFK 902
            G F C   RC       Q+   C  DN C  ++        QHTC SDR +
Sbjct: 367 NGHFHC---RCRPGYTLAQDGKSCQEDNPCQHSNGGC-----QHTCVSDRGR 236

 Score = 32.0 bits (71), Expect = 5.8,   Method: Compositional matrix adjust.
 Identities = 18/48 (37%), Positives = 27/48 (56%), Gaps = 1/48 (2%)
 Frame = -2

Query: 2935 SDERGCH-VNECLSRKLSGCSQDCEDLKIGFKCRCRPGFRLKDDGRTC 2981
            +D R C  ++EC  R    C Q C + +  F C C  G++L +DGR+C
Sbjct: 199  ADGRSCKDIDECAKRN-GDCLQRCVNTQGSFTCTCTQGYQLGNDGRSC 59

 Score = 31.6 bits (70), Expect = 8.2,   Method: Compositional matrix adjust.
 Identities = 18/39 (46%), Positives = 23/39 (58%), Gaps = 1/39 (2%)
 Frame = -2

Query: 2160 CAVANGGCQQLCLYRGGGQRACACAHG-MLAEDGASCRE 2197
            C+V NGGC+ +C     G   C C  G  LA+DG SC+E
Sbjct: 415  CSVXNGGCEHVCTDGYNGHFHCRCRPGYTLAQDGKSCQE 299
>36074
          Length = 478

 Score = 50.4 bits (119), Expect(2) = 1e-11,   Method: Compositional matrix adjust.
 Identities = 26/55 (47%), Positives = 38/55 (69%), Gaps = 2/55 (3%)
 Frame = +1

Query: 3596 DGDHDCADGSDEKDCTPRCDMD-QFQCKS-GHCIPLRWRCDADADCMDGSDEEAC 3648
            +G  +C DG DE++C P CD + +FQC S G CIP+ +RC+   +C D SDE++C
Sbjct: 199  NGRAECRDGRDEQNC-PSCDEETEFQCVSDGRCIPIIYRCNGRPECTDRSDEDSC 360

 Score = 40.0 bits (92), Expect(2) = 1e-11,   Method: Compositional matrix adjust.
 Identities = 24/58 (41%), Positives = 34/58 (58%), Gaps = 1/58 (1%)
 Frame = +3

Query: 3537 CEPYQFRCKNNR-CVPGRWQCDYDNDCGDNSDEESCTPRPCSESEFSCANGRCIAGRW 3593
            C   +F C+ +R C+P   +CD  +DC D SDE  C P  CSE E  C +GRC+  ++
Sbjct: 24   CREDEFTCETSRDCIPASRRCDRRSDCDDGSDERDCGP-VCSEGELEC-DGRCLPPQY 191

 Score = 49.3 bits (116), Expect(2) = 3e-10,   Method: Compositional matrix adjust.
 Identities = 26/58 (44%), Positives = 34/58 (58%), Gaps = 1/58 (1%)
 Frame = +3

Query: 3575 PCSESEFSCANGR-CIAGRWKCDGDHDCADGSDEKDCTPRCDMDQFQCKSGHCIPLRW 3631
            PC E EF+C   R CI    +CD   DC DGSDE+DC P C   + +C  G C+P ++
Sbjct: 21   PCREDEFTCETSRDCIPASRRCDRRSDCDDGSDERDCGPVCSEGELEC-DGRCLPPQY 191

 Score = 36.6 bits (83), Expect(2) = 3e-10,   Method: Compositional matrix adjust.
 Identities = 21/53 (39%), Positives = 33/53 (62%), Gaps = 2/53 (3%)
 Frame = +1

Query: 3637 ADCMDGSDEEACGTGVRTCPLD-EFQC-NNTLCKPLAWKCDGEDDCGDNSDEN 3687
            A+C DG DE+ C +    C  + EFQC ++  C P+ ++C+G  +C D SDE+
Sbjct: 208  AECRDGRDEQNCPS----CDEETEFQCVSDGRCIPIIYRCNGRPECTDRSDED 354

 Score = 46.2 bits (108), Expect(2) = 4e-08,   Method: Compositional matrix adjust.
 Identities = 25/60 (41%), Positives = 33/60 (55%), Gaps = 5/60 (8%)
 Frame = +1

Query: 3395 DGDNDCQDNSDEANCDIHVCLPS-----QFKCTNTNRCIPGIFRCNGQDNCGDGEDERDC 3449
            +G  +C+D  DE NC      PS     +F+C +  RCIP I+RCNG+  C D  DE  C
Sbjct: 199  NGRAECRDGRDEQNC------PSCDEETEFQCVSDGRCIPIIYRCNGRPECTDRSDEDSC 360

 Score = 32.3 bits (72), Expect(2) = 4e-08,   Method: Compositional matrix adjust.
 Identities = 23/60 (38%), Positives = 30/60 (50%), Gaps = 1/60 (1%)
 Frame = +3

Query: 3335 CTASQFVCKNDK-CIPFWWKCDTEDDCGDHSDEPPDCPEFKCRPGQFQCSTGICTNPAFI 3393
            C   +F C+  + CIP   +CD   DC D SDE  DC    C  G+ +C  G C  P +I
Sbjct: 24   CREDEFTCETSRDCIPASRRCDRRSDCDDGSDE-RDCGPV-CSEGELECD-GRCLPPQYI 194

 Score = 47.4 bits (111), Expect(2) = 1e-06,   Method: Compositional matrix adjust.
 Identities = 27/68 (39%), Positives = 38/68 (55%), Gaps = 1/68 (1%)
 Frame = +3

Query: 2687 RDCPGVKRPRCPLNYFACPSGR-CIPMSWTCDKEDDCENGEDETHCNKFCSEAQFECQNH 2745
            R+CP      C  + F C + R CIP S  CD+  DC++G DE  C   CSE + EC + 
Sbjct: 12   RNCP------CREDEFTCETSRDCIPASRRCDRRSDCDDGSDERDCGPVCSEGELEC-DG 170

Query: 2746 RCISKQWL 2753
            RC+  Q++
Sbjct: 171  RCLPPQYI 194

 Score = 26.6 bits (57), Expect(2) = 1e-06,   Method: Compositional matrix adjust.
 Identities = 11/30 (36%), Positives = 17/30 (56%)
 Frame = +1

Query: 2778 SSFSCPGTHVCVPERWLCDGDKDCTDGADE 2807
            + F C     C+P  + C+G  +CTD +DE
Sbjct: 262  TEFQCVSDGRCIPIIYRCNGRPECTDRSDE 351

 Score = 40.4 bits (93), Expect(2) = 2e-06,   Method: Compositional matrix adjust.
 Identities = 27/67 (40%), Positives = 38/67 (56%)
 Frame = +3

Query: 3447 RDCPEVTCAPNQFQCSITKRCIPRVWVCDRDNDCVDGSDEPANCTQMTCGVDEFRCKDSG 3506
            R+CP   C  ++F C  ++ CIP    CDR +DC DGSDE  +C  + C   E  C   G
Sbjct: 12   RNCP---CREDEFTCETSRDCIPASRRCDRRSDCDDGSDE-RDCGPV-CSEGELEC--DG 170

Query: 3507 RCIPARW 3513
            RC+P ++
Sbjct: 171  RCLPPQY 191

 Score = 32.3 bits (72), Expect(2) = 2e-06,   Method: Compositional matrix adjust.
 Identities = 18/44 (40%), Positives = 27/44 (61%), Gaps = 1/44 (2%)
 Frame = +1

Query: 3532 CDERTCEPYQFRC-KNNRCVPGRWQCDYDNDCGDNSDEESCTPR 3574
            CDE T    +F+C  + RC+P  ++C+   +C D SDE+SC  R
Sbjct: 250  CDEET----EFQCVSDGRCIPIIYRCNGRPECTDRSDEDSCQLR 369

 Score = 36.2 bits (82), Expect(2) = 5e-06,   Method: Compositional matrix adjust.
 Identities = 27/58 (46%), Positives = 32/58 (55%), Gaps = 1/58 (1%)
 Frame = +3

Query: 2816 NSTCDDREFMCQ-NRLCIPKHFVCDHDRDCADGSDESPECEYPTCGPNEFRCANGRCL 2872
            N  C + EF C+ +R CIP    CD   DC DGSDE  +C  P C   E  C +GRCL
Sbjct: 15   NCPCREDEFTCETSRDCIPASRRCDRRSDCDDGSDER-DC-GPVCSEGELEC-DGRCL 179

 Score = 35.4 bits (80), Expect(2) = 5e-06,   Method: Compositional matrix adjust.
 Identities = 23/64 (35%), Positives = 33/64 (51%), Gaps = 1/64 (1%)
 Frame = +1

Query: 2880 DGENDCHDHSDEAPKNPHCTSPEHKCNASSQFLC-SSGRCVAEALLCNGQDDCGDGSDER 2938
            +G  +C D  DE     +C S    C+  ++F C S GRC+     CNG+ +C D SDE 
Sbjct: 199  NGRAECRDGRDEQ----NCPS----CDEETEFQCVSDGRCIPIIYRCNGRPECTDRSDED 354

Query: 2939 GCHV 2942
             C +
Sbjct: 355  SCQL 366

 Score = 42.7 bits (99), Expect(2) = 7e-06,   Method: Compositional matrix adjust.
 Identities = 22/52 (42%), Positives = 30/52 (57%)
 Frame = +1

Query: 3435 NGQDNCGDGEDERDCPEVTCAPNQFQCSITKRCIPRVWVCDRDNDCVDGSDE 3486
            NG+  C DG DE++CP       +FQC    RCIP ++ C+   +C D SDE
Sbjct: 199  NGRAECRDGRDEQNCPSCD-EETEFQCVSDGRCIPIIYRCNGRPECTDRSDE 351

 Score = 28.1 bits (61), Expect(2) = 7e-06,   Method: Compositional matrix adjust.
 Identities = 21/59 (35%), Positives = 29/59 (49%), Gaps = 1/59 (1%)
 Frame = +3

Query: 3375 CRPGQFQCSTGI-CTNPAFICDGDNDCQDNSDEANCDIHVCLPSQFKCTNTNRCIPGIF 3432
            CR  +F C T   C   +  CD  +DC D SDE +C   VC   + +C    RC+P  +
Sbjct: 24   CREDEFTCETSRDCIPASRRCDRRSDCDDGSDERDCG-PVCSEGELEC--DGRCLPPQY 191

 Score = 42.0 bits (97), Expect(2) = 8e-05,   Method: Compositional matrix adjust.
 Identities = 22/60 (36%), Positives = 33/60 (55%)
 Frame = +3

Query: 3414 CLPSQFKCTNTNRCIPGIFRCNGQDNCGDGEDERDCPEVTCAPNQFQCSITKRCIPRVWV 3473
            C   +F C  +  CIP   RC+ + +C DG DERDC  V C+  + +C    RC+P  ++
Sbjct: 24   CREDEFTCETSRDCIPASRRCDRRSDCDDGSDERDCGPV-CSEGELECD--GRCLPPQYI 194

 Score = 25.4 bits (54), Expect(2) = 8e-05,   Method: Compositional matrix adjust.
 Identities = 15/38 (39%), Positives = 21/38 (55%), Gaps = 2/38 (5%)
 Frame = +1

Query: 3479 DCVDGSDEP--ANCTQMTCGVDEFRCKDSGRCIPARWK 3514
            +C DG DE    +C + T    EF+C   GRCIP  ++
Sbjct: 211  ECRDGRDEQNCPSCDEET----EFQCVSDGRCIPIIYR 312

 Score = 47.0 bits (110), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 28/70 (40%), Positives = 37/70 (52%)
 Frame = +1

Query: 1030 PEHWTCDGDNDCGDYSDETHANCTNQATRPPGGCHSDEFQCRLDGLCIPLRWRCDGDTDC 1089
            P + + +G  +C D  DE   NC       P      EFQC  DG CIP+ +RC+G  +C
Sbjct: 181  PHNTSGNGRAECRDGRDE--QNC-------PSCDEETEFQCVSDGRCIPIIYRCNGRPEC 333

Query: 1090 MDSSDEKSCE 1099
             D SDE SC+
Sbjct: 334  TDRSDEDSCQ 363

 Score = 36.6 bits (83), Expect(2) = 2e-04,   Method: Compositional matrix adjust.
 Identities = 23/57 (40%), Positives = 29/57 (50%), Gaps = 1/57 (1%)
 Frame = +3

Query: 3614 CDMDQFQCKSGH-CIPLRWRCDADADCMDGSDEEACGTGVRTCPLDEFQCNNTLCKP 3669
            C  D+F C++   CIP   RCD  +DC DGSDE  CG     C   E +C+     P
Sbjct: 24   CREDEFTCETSRDCIPASRRCDRRSDCDDGSDERDCGP---VCSEGELECDGRCLPP 185

 Score = 29.3 bits (64), Expect(2) = 2e-04,   Method: Compositional matrix adjust.
 Identities = 19/59 (32%), Positives = 30/59 (50%)
 Frame = +1

Query: 3675 DGEDDCGDNSDENPEECARFICPPNRPFRCKNDRVCLWIGRQCDGVDNCGDGTDEEDCE 3733
            +G  +C D  DE  + C    C     F+C +D  C+ I  +C+G   C D +DE+ C+
Sbjct: 199  NGRAECRDGRDE--QNCPS--CDEETEFQCVSDGRCIPIIYRCNGRPECTDRSDEDSCQ 363

 Score = 31.6 bits (70), Expect(2) = 0.001,   Method: Compositional matrix adjust.
 Identities = 19/63 (30%), Positives = 27/63 (42%)
 Frame = +3

Query: 2775 CGPSSFSCPGTHVCVPERWLCDGDKDCTDGADESVTAGCLYNSTCDDREFMCQNRLCIPK 2834
            C    F+C  +  C+P    CD   DC DG+DE           C + E  C  R C+P 
Sbjct: 24   CREDEFTCETSRDCIPASRRCDRRSDCDDGSDERDCG-----PVCSEGELECDGR-CLPP 185

Query: 2835 HFV 2837
             ++
Sbjct: 186  QYI 194

 Score = 31.2 bits (69), Expect(2) = 0.001,   Method: Compositional matrix adjust.
 Identities = 21/52 (40%), Positives = 30/52 (57%), Gaps = 3/52 (5%)
 Frame = +1

Query: 2843 DCADGSDES--PECEYPTCGPNEFRC-ANGRCLSSRQWECDGENDCHDHSDE 2891
            +C DG DE   P C+  T    EF+C ++GRC+    + C+G  +C D SDE
Sbjct: 211  ECRDGRDEQNCPSCDEET----EFQCVSDGRCIPI-IYRCNGRPECTDRSDE 351

 Score = 34.7 bits (78), Expect(2) = 0.002,   Method: Compositional matrix adjust.
 Identities = 20/59 (33%), Positives = 29/59 (49%), Gaps = 1/59 (1%)
 Frame = +1

Query: 2675 DGANDCGDYSDERDCPGVKRPRCPLNYFACPS-GRCIPMSWTCDKEDDCENGEDETHCN 2732
            +G  +C D  DE++CP           F C S GRCIP+ + C+   +C +  DE  C 
Sbjct: 199  NGRAECRDGRDEQNCPSCDEE----TEFQCVSDGRCIPIIYRCNGRPECTDRSDEDSCQ 363

 Score = 28.1 bits (61), Expect(2) = 0.002,   Method: Compositional matrix adjust.
 Identities = 16/36 (44%), Positives = 20/36 (55%), Gaps = 1/36 (2%)
 Frame = +3

Query: 2606 CGVGEFRCRDG-SCIGNSSRCNQFVDCEDASDEMNC 2640
            C   EF C     CI  S RC++  DC+D SDE +C
Sbjct: 24   CREDEFTCETSRDCIPASRRCDRRSDCDDGSDERDC 131

 Score = 40.8 bits (94), Expect = 0.013,   Method: Compositional matrix adjust.
 Identities = 23/57 (40%), Positives = 35/57 (61%), Gaps = 1/57 (1%)
 Frame = +1

Query: 3561 DCGDNSDEESCTPRPCSESEFSC-ANGRCIAGRWKCDGDHDCADGSDEKDCTPRCDM 3616
            +C D  DE++C P    E+EF C ++GRCI   ++C+G  +C D SDE  C  R ++
Sbjct: 211  ECRDGRDEQNC-PSCDEETEFQCVSDGRCIPIIYRCNGRPECTDRSDEDSCQLRIEV 378

 Score = 32.0 bits (71), Expect(2) = 0.028,   Method: Compositional matrix adjust.
 Identities = 24/55 (43%), Positives = 29/55 (52%), Gaps = 1/55 (1%)
 Frame = +1

Query: 2587 NGVDDCGDGSDEIPCNKTACGVGEFRC-RDGSCIGNSSRCNQFVDCEDASDEMNC 2640
            NG  +C DG DE  C  +     EF+C  DG CI    RCN   +C D SDE +C
Sbjct: 199  NGRAECRDGRDEQNC-PSCDEETEFQCVSDGRCIPIIYRCNGRPECTDRSDEDSC 360

 Score = 26.6 bits (57), Expect(2) = 0.028,   Method: Compositional matrix adjust.
 Identities = 18/38 (47%), Positives = 21/38 (55%), Gaps = 1/38 (2%)
 Frame = +3

Query: 2522 NSSCRAQDEFECANG-ECISFSLTCDGVSHCKDKSDEK 2558
            N  CR +DEF C    +CI  S  CD  S C D SDE+
Sbjct: 15   NCPCR-EDEFTCETSRDCIPASRRCDRRSDCDDGSDER 125

 Score = 28.9 bits (63), Expect(2) = 0.22,   Method: Compositional matrix adjust.
 Identities = 19/64 (29%), Positives = 26/64 (40%)
 Frame = +1

Query: 2626 NQFVDCEDASDEMNCSTTDCSSYFRLGVKGVLFQPCERTSLCYAPSWVCDGANDCGDYSD 2685
            N   +C D  DE NC + D  + F+          C     C    + C+G  +C D SD
Sbjct: 199  NGRAECRDGRDEQNCPSCDEETEFQ----------CVSDGRCIPIIYRCNGRPECTDRSD 348

Query: 2686 ERDC 2689
            E  C
Sbjct: 349  EDSC 360

 Score = 26.2 bits (56), Expect(2) = 0.22,   Method: Compositional matrix adjust.
 Identities = 20/54 (37%), Positives = 25/54 (46%), Gaps = 1/54 (1%)
 Frame = +3

Query: 2567 CKKTFRQCNNGR-CVSNMLWCNGVDDCGDGSDEIPCNKTACGVGEFRCRDGSCI 2619
            C++    C   R C+     C+   DC DGSDE  C    C  GE  C DG C+
Sbjct: 24   CREDEFTCETSRDCIPASRRCDRRSDCDDGSDERDCGP-VCSEGELEC-DGRCL 179

 Score = 36.2 bits (82), Expect = 0.27,   Method: Compositional matrix adjust.
 Identities = 18/36 (50%), Positives = 20/36 (55%)
 Frame = +3

Query: 1063 CHSDEFQCRLDGLCIPLRWRCDGDTDCMDSSDEKSC 1098
            C  DEF C     CIP   RCD  +DC D SDE+ C
Sbjct: 24   CREDEFTCETSRDCIPASRRCDRRSDCDDGSDERDC 131

 Score = 28.5 bits (62), Expect(2) = 0.43,   Method: Compositional matrix adjust.
 Identities = 20/61 (32%), Positives = 30/61 (49%), Gaps = 1/61 (1%)
 Frame = +3

Query: 855 CQPGEFACANNR-CIQERWKCDGDNDCLDNSDEAPALCHQHTCPSDRFKCENNRCIPNRW 913
           C+  EF C  +R CI    +CD  +DC D SDE         C     +C + RC+P ++
Sbjct: 24  CREDEFTCETSRDCIPASRRCDRRSDCDDGSDERDC---GPVCSEGELEC-DGRCLPPQY 191

Query: 914 L 914
           +
Sbjct: 192 I 194

 Score = 26.2 bits (56), Expect(2) = 0.43,   Method: Compositional matrix adjust.
 Identities = 17/43 (39%), Positives = 23/43 (53%), Gaps = 2/43 (4%)
 Frame = +1

Query: 916 DGDNDCGNSEDESN-ATCSARTCPPNQFSCAS-GRCIPISWTC 956
           +G  +C +  DE N  +C   T    +F C S GRCIPI + C
Sbjct: 199 NGRAECRDGRDEQNCPSCDEET----EFQCVSDGRCIPIIYRC 315

 Score = 33.5 bits (75), Expect = 2.1,   Method: Compositional matrix adjust.
 Identities = 15/33 (45%), Positives = 20/33 (60%)
 Frame = +3

Query: 3702 FRCKNDRVCLWIGRQCDGVDNCGDGTDEEDCEP 3734
            F C+  R C+   R+CD   +C DG+DE DC P
Sbjct: 39   FTCETSRDCIPASRRCDRRSDCDDGSDERDCGP 137

 Score = 33.1 bits (74), Expect = 2.6,   Method: Compositional matrix adjust.
 Identities = 18/40 (45%), Positives = 23/40 (57%), Gaps = 1/40 (2%)
 Frame = +1

Query: 1009 EAGCSHSCSSTQFKCNS-GRCIPEHWTCDGDNDCGDYSDE 1047
            E  C      T+F+C S GRCIP  + C+G  +C D SDE
Sbjct: 232  EQNCPSCDEETEFQCVSDGRCIPIIYRCNGRPECTDRSDE 351

 Score = 32.7 bits (73), Expect = 3.0,   Method: Compositional matrix adjust.
 Identities = 20/57 (35%), Positives = 31/57 (54%)
 Frame = +1

Query: 2546 DGVSHCKDKSDEKPSYCNSRRCKKTFRQCNNGRCVSNMLWCNGVDDCGDGSDEIPCN 2602
            +G + C+D  DE+   C S   +  F+  ++GRC+  +  CNG  +C D SDE  C 
Sbjct: 199  NGRAECRDGRDEQ--NCPSCDEETEFQCVSDGRCIPIIYRCNGRPECTDRSDEDSCQ 363

 Score = 32.7 bits (73), Expect = 3.5,   Method: Compositional matrix adjust.
 Identities = 20/57 (35%), Positives = 28/57 (49%)
 Frame = +1

Query: 49  DGERDCPDGSDEAPEICPQSKAQRCPPNEHSCLGTELCVPMSRLCNGIQDCMDGSDE 105
           +G  +C DG DE  + CP    +     E  C+    C+P+   CNG  +C D SDE
Sbjct: 199 NGRAECRDGRDE--QNCPSCDEE----TEFQCVSDGRCIPIIYRCNGRPECTDRSDE 351

 Score = 32.3 bits (72), Expect = 4.6,   Method: Compositional matrix adjust.
 Identities = 22/54 (40%), Positives = 26/54 (48%)
 Frame = +3

Query: 2661 CERTSLCYAPSWVCDGANDCGDYSDERDCPGVKRPRCPLNYFACPSGRCIPMSW 2714
            CE +  C   S  CD  +DC D SDERDC     P C      C  GRC+P  +
Sbjct: 45   CETSRDCIPASRRCDRRSDCDDGSDERDCG----PVCSEGELEC-DGRCLPPQY 191

 Score = 31.6 bits (70), Expect = 6.8,   Method: Compositional matrix adjust.
 Identities = 21/58 (36%), Positives = 28/58 (48%), Gaps = 3/58 (5%)
 Frame = +3

Query: 73  CPPNEHSCLGTELCVPMSRLCNGIQDCMDGSDE---GAHCRELRANCSRMGCQHHCVP 127
           C  +E +C  +  C+P SR C+   DC DGSDE   G  C E       + C   C+P
Sbjct: 24  CREDEFTCETSRDCIPASRRCDRRSDCDDGSDERDCGPVCSE-----GELECDGRCLP 182

 Score = 31.6 bits (70), Expect = 7.7,   Method: Compositional matrix adjust.
 Identities = 22/59 (37%), Positives = 30/59 (50%), Gaps = 9/59 (15%)
 Frame = +1

Query: 3317 ACPTNFYLGG-----DGR---TCVSNCTASQFVCKND-KCIPFWWKCDTEDDCGDHSDE 3366
            ACP N    G     DGR    C S    ++F C +D +CIP  ++C+   +C D SDE
Sbjct: 175  ACPHNTSGNGRAECRDGRDEQNCPSCDEETEFQCVSDGRCIPIIYRCNGRPECTDRSDE 351

 Score = 31.2 bits (69), Expect = 9.0,   Method: Compositional matrix adjust.
 Identities = 21/60 (35%), Positives = 28/60 (46%), Gaps = 1/60 (1%)
 Frame = +3

Query: 896 CPSDRFKCENNR-CIPNRWLCDGDNDCGNSEDESNATCSARTCPPNQFSCASGRCIPISW 954
           C  D F CE +R CIP    CD  +DC +  DE +       C   +  C  GRC+P  +
Sbjct: 24  CREDEFTCETSRDCIPASRRCDRRSDCDDGSDERDC---GPVCSEGELEC-DGRCLPPQY 191
>14418
          Length = 1408

 Score = 62.0 bits (149), Expect = 5e-09,   Method: Compositional matrix adjust.
 Identities = 37/85 (43%), Positives = 46/85 (54%), Gaps = 3/85 (3%)
 Frame = -3

Query: 3613 RCDMDQFQCKSG---HCIPLRWRCDADADCMDGSDEEACGTGVRTCPLDEFQCNNTLCKP 3669
            RC  D+FQC +     CIP  W CD  ADC  G DE  C    R C   +F+CN+  C P
Sbjct: 1238 RCADDEFQCHASPDRDCIPNYWVCDHSADCDGGEDEINCAERSR-CDEGDFRCNDGDCIP 1062

Query: 3670 LAWKCDGEDDCGDNSDENPEECARF 3694
              W CDG+DDC +  DE+   C+ F
Sbjct: 1061 GDWLCDGDDDCQEGEDEDTTVCSAF 987

 Score = 60.5 bits (145), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 35/86 (40%), Positives = 47/86 (54%), Gaps = 3/86 (3%)
 Frame = -3

Query: 2809 VTAGCLYNSTCDDREFMCQ---NRLCIPKHFVCDHDRDCADGSDESPECEYPTCGPNEFR 2865
            V+    Y++ C D EF C    +R CIP ++VCDH  DC  G DE    E   C   +FR
Sbjct: 1265 VSTRSTYHARCADDEFQCHASPDRDCIPNYWVCDHSADCDGGEDEINCAERSRCDEGDFR 1086

Query: 2866 CANGRCLSSRQWECDGENDCHDHSDE 2891
            C +G C+    W CDG++DC +  DE
Sbjct: 1085 CNDGDCIPG-DWLCDGDDDCQEGEDE 1011

 Score = 59.3 bits (142), Expect = 4e-08,   Method: Compositional matrix adjust.
 Identities = 32/75 (42%), Positives = 41/75 (54%), Gaps = 4/75 (5%)
 Frame = -3

Query: 3537 CEPYQFRCK---NNRCVPGRWQCDYDNDCGDNSDEESCTPRP-CSESEFSCANGRCIAGR 3592
            C   +F+C    +  C+P  W CD+  DC    DE +C  R  C E +F C +G CI G 
Sbjct: 1235 CADDEFQCHASPDRDCIPNYWVCDHSADCDGGEDEINCAERSRCDEGDFRCNDGDCIPGD 1056

Query: 3593 WKCDGDHDCADGSDE 3607
            W CDGD DC +G DE
Sbjct: 1055 WLCDGDDDCQEGEDE 1011

 Score = 57.8 bits (138), Expect = 9e-08,   Method: Compositional matrix adjust.
 Identities = 33/76 (43%), Positives = 40/76 (52%), Gaps = 5/76 (6%)
 Frame = -3

Query: 3576 CSESEFSC---ANGRCIAGRWKCDGDHDCADGSDEKDCTPR--CDMDQFQCKSGHCIPLR 3630
            C++ EF C    +  CI   W CD   DC  G DE +C  R  CD   F+C  G CIP  
Sbjct: 1235 CADDEFQCHASPDRDCIPNYWVCDHSADCDGGEDEINCAERSRCDEGDFRCNDGDCIPGD 1056

Query: 3631 WRCDADADCMDGSDEE 3646
            W CD D DC +G DE+
Sbjct: 1055 WLCDGDDDCQEGEDED 1008

 Score = 55.1 bits (131), Expect = 6e-07,   Method: Compositional matrix adjust.
 Identities = 32/74 (43%), Positives = 40/74 (54%), Gaps = 2/74 (2%)
 Frame = -3

Query: 2667 CYAPSWVCDGANDCGDYSDERDCPGVKRPRCPLNYFACPSGRCIPMSWTCDKEDDCENGE 2726
            C    WVCD + DC    DE +C   +R RC    F C  G CIP  W CD +DDC+ GE
Sbjct: 1190 CIPNYWVCDHSADCDGGEDEINC--AERSRCDEGDFRCNDGDCIPGDWLCDGDDDCQEGE 1017

Query: 2727 DE--THCNKFCSEA 2738
            DE  T C+ F  ++
Sbjct: 1016 DEDTTVCSAFSQDS 975

 Score = 53.9 bits (128), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 33/84 (39%), Positives = 39/84 (46%), Gaps = 3/84 (3%)
 Frame = -3

Query: 854  QCQPGEFAC---ANNRCIQERWKCDGDNDCLDNSDEAPALCHQHTCPSDRFKCENNRCIP 910
            +C   EF C    +  CI   W CD   DC    DE      +  C    F+C +  CIP
Sbjct: 1238 RCADDEFQCHASPDRDCIPNYWVCDHSADCDGGEDEINCA-ERSRCDEGDFRCNDGDCIP 1062

Query: 911  NRWLCDGDNDCGNSEDESNATCSA 934
              WLCDGD+DC   EDE    CSA
Sbjct: 1061 GDWLCDGDDDCQEGEDEDTTVCSA 990

 Score = 50.8 bits (120), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 32/85 (37%), Positives = 44/85 (51%), Gaps = 3/85 (3%)
 Frame = -3

Query: 1016 CSSTQFKCNSG---RCIPEHWTCDGDNDCGDYSDETHANCTNQATRPPGGCHSDEFQCRL 1072
            C+  +F+C++     CIP +W CD   DC    DE   NC  ++      C   +F+C  
Sbjct: 1235 CADDEFQCHASPDRDCIPNYWVCDHSADCDGGEDEI--NCAERSR-----CDEGDFRCN- 1080

Query: 1073 DGLCIPLRWRCDGDTDCMDSSDEKS 1097
            DG CIP  W CDGD DC +  DE +
Sbjct: 1079 DGDCIPGDWLCDGDDDCQEGEDEDT 1005

 Score = 50.8 bits (120), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 39/133 (29%), Positives = 48/133 (36%), Gaps = 5/133 (3%)
 Frame = -3

Query: 2696 RCPLNYFAC---PSGRCIPMSWTCDKEDDCENGEDETHCNK--FCSEAQFECQNHRCISK 2750
            RC  + F C   P   CIP  W CD   DC+ GEDE +C +   C E  F C +  CI  
Sbjct: 1238 RCADDEFQCHASPDRDCIPNYWVCDHSADCDGGEDEINCAERSRCDEGDFRCNDGDCI-- 1065

Query: 2751 QWLXXXXXXXXXXXXEAAHCEGKTCGPSSFSCPGTHVCVPERWLCDGDKDCTDGADESVT 2810
                                                   P  WLCDGD DC +G DE  T
Sbjct: 1064 ---------------------------------------PGDWLCDGDDDCQEGEDEDTT 1002

Query: 2811 AGCLYNSTCDDRE 2823
                ++   D +E
Sbjct: 1001 VCSAFSQDSDSQE 963

 Score = 50.1 bits (118), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 29/65 (44%), Positives = 37/65 (56%), Gaps = 3/65 (4%)
 Frame = -3

Query: 3452 VTCAPNQFQC--SITKRCIPRVWVCDRDNDCVDGSDEPANCTQMT-CGVDEFRCKDSGRC 3508
              CA ++FQC  S  + CIP  WVCD   DC DG ++  NC + + C   +FRC D G C
Sbjct: 1241 ARCADDEFQCHASPDRDCIPNYWVCDHSADC-DGGEDEINCAERSRCDEGDFRCND-GDC 1068

Query: 3509 IPARW 3513
            IP  W
Sbjct: 1067 IPGDW 1053

 Score = 50.1 bits (118), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 28/77 (36%), Positives = 39/77 (50%), Gaps = 3/77 (3%)
 Frame = -3

Query: 3333 SNCTASQFVCK---NDKCIPFWWKCDTEDDCGDHSDEPPDCPEFKCRPGQFQCSTGICTN 3389
            + C   +F C    +  CIP +W CD   DC    DE       +C  G F+C+ G C  
Sbjct: 1241 ARCADDEFQCHASPDRDCIPNYWVCDHSADCDGGEDEINCAERSRCDEGDFRCNDGDCIP 1062

Query: 3390 PAFICDGDNDCQDNSDE 3406
              ++CDGD+DCQ+  DE
Sbjct: 1061 GDWLCDGDDDCQEGEDE 1011

 Score = 48.9 bits (115), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 28/65 (43%), Positives = 33/65 (50%), Gaps = 4/65 (6%)
 Frame = -3

Query: 896  CPSDRFKCE---NNRCIPNRWLCDGDNDCGNSEDESNATCSART-CPPNQFSCASGRCIP 951
            C  D F+C    +  CIPN W+CD   DC   EDE N  C+ R+ C    F C  G CIP
Sbjct: 1235 CADDEFQCHASPDRDCIPNYWVCDHSADCDGGEDEIN--CAERSRCDEGDFRCNDGDCIP 1062

Query: 952  ISWTC 956
              W C
Sbjct: 1061 GDWLC 1047

 Score = 47.8 bits (112), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 29/76 (38%), Positives = 42/76 (55%), Gaps = 3/76 (3%)
 Frame = -3

Query: 3414 CLPSQFKCTNT--NRCIPGIFRCNGQDNCGDGEDERDCPEVT-CAPNQFQCSITKRCIPR 3470
            C   +F+C  +    CIP  + C+   +C  GEDE +C E + C    F+C+    CIP 
Sbjct: 1235 CADDEFQCHASPDRDCIPNYWVCDHSADCDGGEDEINCAERSRCDEGDFRCNDGD-CIPG 1059

Query: 3471 VWVCDRDNDCVDGSDE 3486
             W+CD D+DC +G DE
Sbjct: 1058 DWLCDGDDDCQEGEDE 1011

 Score = 45.8 bits (107), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 32/87 (36%), Positives = 44/87 (50%), Gaps = 4/87 (4%)
 Frame = -3

Query: 2566 RCKKTFRQCN---NGRCVSNMLWCNGVDDCGDGSDEIPC-NKTACGVGEFRCRDGSCIGN 2621
            RC     QC+   +  C+ N   C+   DC  G DEI C  ++ C  G+FRC DG CI  
Sbjct: 1238 RCADDEFQCHASPDRDCIPNYWVCDHSADCDGGEDEINCAERSRCDEGDFRCNDGDCIPG 1059

Query: 2622 SSRCNQFVDCEDASDEMNCSTTDCSSY 2648
               C+   DC++  DE    TT CS++
Sbjct: 1058 DWLCDGDDDCQEGEDE---DTTVCSAF 987

 Score = 44.7 bits (104), Expect = 8e-04,   Method: Compositional matrix adjust.
 Identities = 29/77 (37%), Positives = 39/77 (50%), Gaps = 4/77 (5%)
 Frame = -3

Query: 3374 KCRPGQFQCSTGI---CTNPAFICDGDNDCQDNSDEANC-DIHVCLPSQFKCTNTNRCIP 3429
            +C   +FQC       C    ++CD   DC    DE NC +   C    F+C N   CIP
Sbjct: 1238 RCADDEFQCHASPDRDCIPNYWVCDHSADCDGGEDEINCAERSRCDEGDFRC-NDGDCIP 1062

Query: 3430 GIFRCNGQDNCGDGEDE 3446
            G + C+G D+C +GEDE
Sbjct: 1061 GDWLCDGDDDCQEGEDE 1011

 Score = 40.8 bits (94), Expect = 0.013,   Method: Compositional matrix adjust.
 Identities = 18/38 (47%), Positives = 22/38 (57%)
 Frame = -3

Query: 1016 CSSTQFKCNSGRCIPEHWTCDGDNDCGDYSDETHANCT 1053
            C    F+CN G CIP  W CDGD+DC +  DE    C+
Sbjct: 1106 CDEGDFRCNDGDCIPGDWLCDGDDDCQEGEDEDTTVCS 993

 Score = 39.3 bits (90), Expect = 0.039,   Method: Compositional matrix adjust.
 Identities = 29/68 (42%), Positives = 32/68 (47%), Gaps = 2/68 (2%)
 Frame = -3

Query: 1063 CHSDEFQCRL--DGLCIPLRWRCDGDTDCMDSSDEKSCEGVTHVCDPNVKFGCKDSARCI 1120
            C  DEFQC    D  CIP  W CD   DC    DE +C   +  CD    F C D   CI
Sbjct: 1235 CADDEFQCHASPDRDCIPNYWVCDHSADCDGGEDEINCAERSR-CDEG-DFRCND-GDCI 1065

Query: 1121 SKAWVCDG 1128
               W+CDG
Sbjct: 1064 PGDWLCDG 1041

 Score = 38.5 bits (88), Expect = 0.062,   Method: Compositional matrix adjust.
 Identities = 28/76 (36%), Positives = 38/76 (50%), Gaps = 4/76 (5%)
 Frame = -3

Query: 2527 AQDEFEC---ANGECISFSLTCDGVSHCKDKSDEKPSYCNSR-RCKKTFRQCNNGRCVSN 2582
            A DEF+C    + +CI     CD  + C    DE    C  R RC +   +CN+G C+  
Sbjct: 1232 ADDEFQCHASPDRDCIPNYWVCDHSADCDGGEDEI--NCAERSRCDEGDFRCNDGDCIPG 1059

Query: 2583 MLWCNGVDDCGDGSDE 2598
               C+G DDC +G DE
Sbjct: 1058 DWLCDGDDDCQEGEDE 1011

 Score = 35.8 bits (81), Expect = 0.38,   Method: Compositional matrix adjust.
 Identities = 31/79 (39%), Positives = 37/79 (46%), Gaps = 3/79 (3%)
 Frame = -3

Query: 3655 CPLDEFQCN---NTLCKPLAWKCDGEDDCGDNSDENPEECARFICPPNRPFRCKNDRVCL 3711
            C  DEFQC+   +  C P  W CD   DC    DE    CA         FRC ND  C+
Sbjct: 1235 CADDEFQCHASPDRDCIPNYWVCDHSADCDGGEDEI--NCAERSRCDEGDFRC-NDGDCI 1065

Query: 3712 WIGRQCDGVDNCGDGTDEE 3730
                 CDG D+C +G DE+
Sbjct: 1064 PGDWLCDGDDDCQEGEDED 1008

 Score = 34.3 bits (77), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 26/80 (32%), Positives = 35/80 (43%), Gaps = 2/80 (2%)
 Frame = -3

Query: 28   CSPKQFACR--DQITCISKGWRCDGERDCPDGSDEAPEICPQSKAQRCPPNEHSCLGTEL 85
            C+  +F C       CI   W CD   DC  G DE       ++  RC   +  C   + 
Sbjct: 1235 CADDEFQCHASPDRDCIPNYWVCDHSADCDGGEDEIN----CAERSRCDEGDFRCNDGD- 1071

Query: 86   CVPMSRLCNGIQDCMDGSDE 105
            C+P   LC+G  DC +G DE
Sbjct: 1070 CIPGDWLCDGDDDCQEGEDE 1011
>07364
          Length = 985

 Score = 60.5 bits (145), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 55/153 (35%), Positives = 63/153 (41%), Gaps = 1/153 (0%)
 Frame = -1

Query: 4201 CTLQCFNGGSCFLNARRQPKCRCQPRYTGDKCELDQCWEYCHNGGTCAASPSGMPTCRCP 4260
            C   C NGG C     R  +CRC   Y G  CE   C   C NGG C A       C CP
Sbjct: 823  CHKTCHNGGQCI----RHDRCRCAKGYKGRYCETPVCGRGCVNGGKCVAPRR----CSCP 668

Query: 4261 TGFTGPKCTAQVCAGYCSNNSTCTVNQGNQPQCRCLPGFLGDRCQYRQCSGFCENFGTCQ 4320
            +G+ G +C    C   C N   C         C C P  LG RC+   C   C N G C 
Sbjct: 667  SGYRGRRCQKPRCRPSCKNGGKCIAPG----ICLCPPSLLGPRCRRHTCRKKCRNGGRC- 503

Query: 4321 MAADGSRQCRCTVYFEGPRCEVNKCS-RCLQGA 4352
              A+G  +C C   F G  C   KC+  CL G 
Sbjct: 502  -VANG--KCLCPPSFYGRYCHRAKCNLTCLNGG 413

 Score = 59.7 bits (143), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 63/194 (32%), Positives = 75/194 (38%), Gaps = 3/194 (1%)
 Frame = -1

Query: 4221 CRCQPRYTGDKCELDQCWEYCHNGGTCAASPSGMPTCRCPTGFTGPKCTAQVCAGYCSNN 4280
            C C   +TG  CE   C   C NGG C  +      C CP G+TG  C    C   C N 
Sbjct: 964  CHCPHNFTGLSCETPHCDPPCLNGGYCTMT----AVCACPYGYTGVDCQP-YCHKTCHNG 800

Query: 4281 STCTVNQGNQPQCRCLPGFLGDRCQYRQCSGFCENFGTCQMAADGSRQCRCTVYFEGPRC 4340
              C  +     +CRC  G+ G  C+   C   C N G C       R+C C   + G RC
Sbjct: 799  GQCIRHD----RCRCAKGYKGRYCETPVCGRGCVNGGKCVAP----RRCSCPSGYRGRRC 644

Query: 4341 EVNKC-SRCLQGACVVNKQTGDVTCNCTDGRVAPSCL--TCIDHCSNGGSCTMNSKMMPE 4397
            +  +C   C  G     K      C C    + P C   TC   C NGG C  N K    
Sbjct: 643  QKPRCRPSCKNGG----KCIAPGICLCPPSLLGPRCRRHTCRKKCRNGGRCVANGK---- 488

Query: 4398 CQCPPHMTGPRCEE 4411
            C CPP   G  C  
Sbjct: 487  CLCPPSFYGRYCHR 446

 Score = 53.1 bits (126), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 69/216 (31%), Positives = 82/216 (37%), Gaps = 4/216 (1%)
 Frame = -1

Query: 4201 CTLQCFNGGSCFLNARRQPKCRCQPRYTGDKCELDQCWEYCHNGGTCAASPSGMPTCRCP 4260
            C   C NGG C + A     C C   YTG  C+   C + CHNGG C         CRC 
Sbjct: 916  CDPPCLNGGYCTMTA----VCACPYGYTGVDCQ-PYCHKTCHNGGQCIRHDR----CRCA 764

Query: 4261 TGFTGPKCTAQVCAGYCSNNSTCTVNQGNQPQCRCLPGFLGDRCQYRQCSGFCENFGTCQ 4320
             G+ G  C   VC   C N   C   +    +C C  G+ G RCQ  +C   C+N G C 
Sbjct: 763  KGYKGRYCETPVCGRGCVNGGKCVAPR----RCSCPSGYRGRRCQKPRCRPSCKNGGKCI 596

Query: 4321 MAADGSRQCRCTVYFEGPRCEVNKC-SRCLQGA-CVVNKQTGDVTCNCTDGRVAPSC--L 4376
                    C C     GPRC  + C  +C  G  CV N +     C C        C   
Sbjct: 595  APGI----CLCPPSLLGPRCRRHTCRKKCRNGGRCVANGK-----CLCPPSFYGRYCHRA 443

Query: 4377 TCIDHCSNGGSCTMNSKMMPECQCPPHMTGPRCEEQ 4412
             C   C NGG C            P    G RCE +
Sbjct: 442  KCNLTCLNGGRCRRRKNRCRC---PKGFRGRRCERR 344

 Score = 52.8 bits (125), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 48/146 (32%), Positives = 57/146 (39%)
 Frame = -1

Query: 4200 TCTLQCFNGGSCFLNARRQPKCRCQPRYTGDKCELDQCWEYCHNGGTCAASPSGMPTCRC 4259
             C   C NGG C    R    C C   Y G +C+  +C   C NGG C A       C C
Sbjct: 730  VCGRGCVNGGKCVAPRR----CSCPSGYRGRRCQKPRCRPSCKNGGKCIAPG----ICLC 575

Query: 4260 PTGFTGPKCTAQVCAGYCSNNSTCTVNQGNQPQCRCLPGFLGDRCQYRQCSGFCENFGTC 4319
            P    GP+C    C   C N   C  N     +C C P F G  C   +C+  C N G C
Sbjct: 574  PPSLLGPRCRRHTCRKKCRNGGRCVANG----KCLCPPSFYGRYCHRAKCNLTCLNGGRC 407

Query: 4320 QMAADGSRQCRCTVYFEGPRCEVNKC 4345
            +   +  R       F G RCE   C
Sbjct: 406  RRRKNRCRC---PKGFRGRRCERRSC 338

 Score = 48.1 bits (113), Expect = 8e-05,   Method: Compositional matrix adjust.
 Identities = 54/165 (32%), Positives = 67/165 (40%), Gaps = 4/165 (2%)
 Frame = -1

Query: 4257 CRCPTGFTGPKCTAQVCAGYCSNNSTCTVNQGNQPQCRCLPGFLGDRCQYRQCSGFCENF 4316
            C CP  FTG  C    C   C N   CT+       C C  G+ G  CQ   C   C N 
Sbjct: 964  CHCPHNFTGLSCETPHCDPPCLNGGYCTMTA----VCACPYGYTGVDCQ-PYCHKTCHNG 800

Query: 4317 GTCQMAADGSRQCRCTVYFEGPRCEVNKCSR-CLQGA-CVVNKQTGDVTCNCTDGRVAPS 4374
            G C +  D   +CRC   ++G  CE   C R C+ G  CV  ++     C+C  G     
Sbjct: 799  GQC-IRHD---RCRCAKGYKGRYCETPVCGRGCVNGGKCVAPRR-----CSCPSGYRGRR 647

Query: 4375 CLT--CIDHCSNGGSCTMNSKMMPECQCPPHMTGPRCEEQVVSQQ 4417
            C    C   C NGG C         C CPP + GPRC      ++
Sbjct: 646  CQKPRCRPSCKNGGKCIAPG----ICLCPPSLLGPRCRRHTCRKK 524
>25877
          Length = 434

 Score = 56.2 bits (134), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 35/87 (40%), Positives = 44/87 (50%), Gaps = 6/87 (6%)
 Frame = -1

Query: 111 ELRANCSRMGC---QHHCVPTPSGPTCYCNSSFQLQADGKTCK--DFDEC-SVYGTCSQL 164
           E    CS + C      C        C+CN+ +QL  D KTC   D D C      C Q 
Sbjct: 410 ETSTTCSELDCDLDNGGCKIVGDSQECFCNTGYQLDGDNKTCIFIDVDWCLQDPSPCDQT 231

Query: 165 CTNTDGSFTCGCVEGYLLQPDNRSCKA 191
           C +TDG FTCGC +G+ L P NR+C+A
Sbjct: 230 CNSTDGKFTCGCFKGFQLNPGNRTCRA 150

 Score = 39.7 bits (91), Expect = 0.025,   Method: Compositional matrix adjust.
 Identities = 27/85 (31%), Positives = 38/85 (44%), Gaps = 3/85 (3%)
 Frame = -1

Query: 1186 CSLNNGGCSHNCSVAPGEGIVCSCPLGMELGSDNHTCQI--QSYCAKHLK-CSQKCDQNK 1242
            C L+NGGC        G+   C C  G +L  DN TC      +C +    C Q C+   
Sbjct: 380  CDLDNGGCK-----IVGDSQECFCNTGYQLDGDNKTCIFIDVDWCLQDPSPCDQTCNSTD 216

Query: 1243 FSVKCSCYEGWVLEPDGESCRSLDP 1267
                C C++G+ L P   +CR+  P
Sbjct: 215  GKFTCGCFKGFQLNPGNRTCRACSP 141

 Score = 34.7 bits (78), Expect = 0.95,   Method: Compositional matrix adjust.
 Identities = 22/65 (33%), Positives = 35/65 (53%), Gaps = 3/65 (4%)
 Frame = -1

Query: 2965 KCRCRPGFRLKDDGRTCA--DLDEC-STTFPCSQLCINTHGSYKCLCVEGYAPRGGDPHS 3021
            +C C  G++L  D +TC   D+D C     PC Q C +T G + C C +G+    G+  +
Sbjct: 335  ECFCNTGYQLDGDNKTCIFIDVDWCLQDPSPCDQTCNSTDGKFTCGCFKGFQLNPGN-RT 159

Query: 3022 CKAVT 3026
            C+A +
Sbjct: 158  CRACS 144
>25748
          Length = 425

 Score = 56.2 bits (134), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 30/66 (45%), Positives = 41/66 (62%), Gaps = 2/66 (3%)
 Frame = +2

Query: 120 GCQHHCVPTPSGP-TCYCNSSFQLQADGKTCKDFDEC-SVYGTCSQLCTNTDGSFTCGCV 177
           GC+  CV  P G   C C S +Q+ +DG  C+D +EC  + G C Q C NT+GS+ C C 
Sbjct: 143 GCEQLCVTEPGGEFRCDCYSGYQITSDGVHCEDVNECRELNGGCEQDCYNTEGSYQCACQ 322

Query: 178 EGYLLQ 183
           EGY+L+
Sbjct: 323 EGYILR 340

 Score = 52.4 bits (124), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 34/84 (40%), Positives = 45/84 (53%), Gaps = 4/84 (4%)
 Frame = +2

Query: 2948 RKLSGCSQDCEDLKIG-FKCRCRPGFRLKDDGRTCADLDEC-STTFPCSQLCINTHGSYK 3005
            ++  GC Q C     G F+C C  G+++  DG  C D++EC      C Q C NT GSY+
Sbjct: 131  QRNGGCEQLCVTEPGGEFRCDCYSGYQITSDGVHCEDVNECRELNGGCEQDCYNTEGSYQ 310

Query: 3006 CLCVEGYAPRGG--DPHSCKAVTD 3027
            C C EGY  R G  +   C+AV D
Sbjct: 311  CACQEGYILRRGRNNQDVCEAVCD 382

 Score = 40.4 bits (93), Expect = 0.015,   Method: Compositional matrix adjust.
 Identities = 24/71 (33%), Positives = 35/71 (49%), Gaps = 1/71 (1%)
 Frame = +2

Query: 1186 CSLNNGGCSHNCSVAPGEGIVCSCPLGMELGSDNHTCQIQSYCAK-HLKCSQKCDQNKFS 1244
            C   NGGC   C   PG    C C  G ++ SD   C+  + C + +  C Q C   + S
Sbjct: 125  CEQRNGGCEQLCVTEPGGEFRCDCYSGYQITSDGVHCEDVNECRELNGGCEQDCYNTEGS 304

Query: 1245 VKCSCYEGWVL 1255
             +C+C EG++L
Sbjct: 305  YQCACQEGYIL 337

 Score = 37.4 bits (85), Expect = 0.13,   Method: Compositional matrix adjust.
 Identities = 24/75 (32%), Positives = 35/75 (46%), Gaps = 2/75 (2%)
 Frame = +2

Query: 3783 LTSCATNASMCGDEARCVRTEKAAY-CACRSGFHTVPGQPGCQDINECLRF-GTCSQLCN 3840
            ++SC      C  E  CV      + C C SG+        C+D+NEC    G C Q C 
Sbjct: 116  ISSCEQRNGGC--EQLCVTEPGGEFRCDCYSGYQITSDGVHCEDVNECRELNGGCEQDCY 289

Query: 3841 NTKGGHLCSCARNFM 3855
            NT+G + C+C   ++
Sbjct: 290  NTEGSYQCACQEGYI 334

 Score = 37.0 bits (84), Expect = 0.17,   Method: Compositional matrix adjust.
 Identities = 25/76 (32%), Positives = 31/76 (40%), Gaps = 2/76 (2%)
 Frame = +2

Query: 121 CQHHCVPTPSGPTCYCNSSFQLQADGKTCKDFDECSVY-GTCSQLC-TNTDGSFTCGCVE 178
           C+++C        C C     L  DG  C+    C    G C QLC T   G F C C  
Sbjct: 23  CEYYCTNLEGSFECSCPQHLVLAPDGLNCEAISSCEQRNGGCEQLCVTEPGGEFRCDCYS 202

Query: 179 GYLLQPDNRSCKAKNE 194
           GY +  D   C+  NE
Sbjct: 203 GYQITSDGVHCEDVNE 250

 Score = 36.2 bits (82), Expect = 0.34,   Method: Compositional matrix adjust.
 Identities = 23/69 (33%), Positives = 32/69 (46%), Gaps = 6/69 (8%)
 Frame = +2

Query: 3283 HALRQPDVPN----HPCKVNNGGCSNLCLLSPGGGHKCACPTNFYLGGDGRTC--VSNCT 3336
            H +  PD  N      C+  NGGC  LC+  PGG  +C C + + +  DG  C  V+ C 
Sbjct: 77   HLVLAPDGLNCEAISSCEQRNGGCEQLCVTEPGGEFRCDCYSGYQITSDGVHCEDVNECR 256

Query: 3337 ASQFVCKND 3345
                 C+ D
Sbjct: 257  ELNGGCEQD 283

 Score = 34.7 bits (78), Expect = 0.94,   Method: Compositional matrix adjust.
 Identities = 17/32 (53%), Positives = 19/32 (59%)
 Frame = +2

Query: 805 TNKCRVNNGGCSSLCLATPGSRQCACAEDQVL 836
            N+CR  NGGC   C  T GS QCAC E  +L
Sbjct: 242 VNECRELNGGCEQDCYNTEGSYQCACQEGYIL 337

 Score = 31.6 bits (70), Expect = 8.1,   Method: Compositional matrix adjust.
 Identities = 19/69 (27%), Positives = 27/69 (39%), Gaps = 7/69 (10%)
 Frame = +2

Query: 2465 PMGIIAVANDTNSCELSPCRINNGGCQDLCLLTHQGHVNCSCRGGRILQEDFT------- 2517
            P  ++   +  N   +S C   NGGC+ LC+    G   C C  G  +  D         
Sbjct: 71   PQHLVLAPDGLNCEAISSCEQRNGGCEQLCVTEPGGEFRCDCYSGYQITSDGVHCEDVNE 250

Query: 2518 CRAVNSSCR 2526
            CR +N  C 
Sbjct: 251  CRELNGGCE 277

 Score = 31.2 bits (69), Expect = 9.3,   Method: Compositional matrix adjust.
 Identities = 19/48 (39%), Positives = 24/48 (50%), Gaps = 7/48 (14%)
 Frame = +2

Query: 2160 CAVANGGCQQLCLYRGGGQRACAC-------AHGMLAEDGASCREYAG 2200
            C   NGGC+QLC+   GG+  C C       + G+  ED   CRE  G
Sbjct: 125  CEQRNGGCEQLCVTEPGGEFRCDCYSGYQITSDGVHCEDVNECRELNG 268
>14371
          Length = 627

 Score = 55.1 bits (131), Expect = 7e-07,   Method: Compositional matrix adjust.
 Identities = 29/66 (43%), Positives = 41/66 (62%), Gaps = 1/66 (1%)
 Frame = +3

Query: 2953 CSQDCEDLKIGFKCRCRPGFRLKDDGRTCADLDECST-TFPCSQLCINTHGSYKCLCVEG 3011
            C+Q C++L   ++C C  G+RL D+GR C D++EC   +  CS  C+NT GSY+C C  G
Sbjct: 102  CAQSCQNLIGSYRCSCTRGYRLGDNGR-CIDINECEQPSTKCSHDCVNTPGSYRCACPVG 278

Query: 3012 YAPRGG 3017
            Y    G
Sbjct: 279  YRLTAG 296

 Score = 39.7 bits (91), Expect = 0.024,   Method: Compositional matrix adjust.
 Identities = 28/86 (32%), Positives = 39/86 (45%), Gaps = 1/86 (1%)
 Frame = +3

Query: 136 CNSSFQLQADGKTCKDFDECS-VYGTCSQLCTNTDGSFTCGCVEGYLLQPDNRSCKAKNE 194
           C + F+   DG  C+D +EC+     C+Q C N  GS+ C C  GY L  DN  C   NE
Sbjct: 24  CGNGFRRSQDGSKCEDINECADTPEVCAQSCQNLIGSYRCSCTRGYRL-GDNGRCIDINE 200

Query: 195 PVDRPPVLLIANSQNILATYLSGAQV 220
             ++P      +  N   +Y     V
Sbjct: 201 -CEQPSTKCSHDCVNTPGSYRCACPV 275

 Score = 32.7 bits (73), Expect = 3.5,   Method: Compositional matrix adjust.
 Identities = 17/40 (42%), Positives = 22/40 (55%), Gaps = 1/40 (2%)
 Frame = +3

Query: 151 DFDECSVYG-TCSQLCTNTDGSFTCGCVEGYLLQPDNRSC 189
           D +EC +    C   C+NT GS+ C C +GY L  D  SC
Sbjct: 507 DINECRLRSDICQHNCSNTRGSYQCSCPKGYRLAADGYSC 626

 Score = 32.0 bits (71), Expect = 5.7,   Method: Compositional matrix adjust.
 Identities = 18/47 (38%), Positives = 23/47 (48%), Gaps = 1/47 (2%)
 Frame = +3

Query: 3809 ACRSGFHTVPGQPGCQDINECLRF-GTCSQLCNNTKGGHLCSCARNF 3854
             C +GF        C+DINEC      C+Q C N  G + CSC R +
Sbjct: 21   VCGNGFRRSQDGSKCEDINECADTPEVCAQSCQNLIGSYRCSCTRGY 161
>29665
          Length = 308

 Score = 55.1 bits (131), Expect = 7e-07,   Method: Compositional matrix adjust.
 Identities = 33/74 (44%), Positives = 37/74 (50%)
 Frame = +3

Query: 3566 SDEESCTPRPCSESEFSCANGRCIAGRWKCDGDHDCADGSDEKDCTPRCDMDQFQCKSGH 3625
            SDE +C      + EF C  G CI    +CDG  DC D SDE  CTP C   +F C  G 
Sbjct: 6    SDERNCDCN--FDFEFQCDMGVCIRSYERCDGKTDCPDQSDEAGCTPNCTNGRFTCDDGT 179

Query: 3626 CIPLRWRCDADADC 3639
            CI   W CD   DC
Sbjct: 180  CIMAEWVCDGQYDC 221

 Score = 54.7 bits (130), Expect = 8e-07,   Method: Compositional matrix adjust.
 Identities = 30/72 (41%), Positives = 40/72 (55%), Gaps = 3/72 (4%)
 Frame = +3

Query: 3533 DERTCE---PYQFRCKNNRCVPGRWQCDYDNDCGDNSDEESCTPRPCSESEFSCANGRCI 3589
            DER C+    ++F+C    C+    +CD   DC D SDE  CTP  C+   F+C +G CI
Sbjct: 9    DERNCDCNFDFEFQCDMGVCIRSYERCDGKTDCPDQSDEAGCTPN-CTNGRFTCDDGTCI 185

Query: 3590 AGRWKCDGDHDC 3601
               W CDG +DC
Sbjct: 186  MAEWVCDGQYDC 221

 Score = 47.8 bits (112), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 28/69 (40%), Positives = 38/69 (55%)
 Frame = +3

Query: 2863 EFRCANGRCLSSRQWECDGENDCHDHSDEAPKNPHCTSPEHKCNASSQFLCSSGRCVAEA 2922
            EF+C  G C+ S +  CDG+ DC D SDEA   P+CT        + +F C  G C+   
Sbjct: 42   EFQCDMGVCIRSYE-RCDGKTDCPDQSDEAGCTPNCT--------NGRFTCDDGTCIMAE 194

Query: 2923 LLCNGQDDC 2931
             +C+GQ DC
Sbjct: 195  WVCDGQYDC 221

 Score = 46.2 bits (108), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 27/63 (42%), Positives = 33/63 (52%)
 Frame = +3

Query: 859 EFACANNRCIQERWKCDGDNDCLDNSDEAPALCHQHTCPSDRFKCENNRCIPNRWLCDGD 918
           EF C    CI+   +CDG  DC D SDEA        C + RF C++  CI   W+CDG 
Sbjct: 42  EFQCDMGVCIRSYERCDGKTDCPDQSDEAGCT---PNCTNGRFTCDDGTCIMAEWVCDGQ 212

Query: 919 NDC 921
            DC
Sbjct: 213 YDC 221

 Score = 45.4 bits (106), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 32/62 (51%), Positives = 35/62 (56%)
 Frame = +3

Query: 1067 EFQCRLDGLCIPLRWRCDGDTDCMDSSDEKSCEGVTHVCDPNVKFGCKDSARCISKAWVC 1126
            EFQC + G+CI    RCDG TDC D SDE    G T  C  N +F C D   CI   WVC
Sbjct: 42   EFQCDM-GVCIRSYERCDGKTDCPDQSDEA---GCTPNC-TNGRFTCDDGT-CIMAEWVC 203

Query: 1127 DG 1128
            DG
Sbjct: 204  DG 209

 Score = 43.1 bits (100), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 37/97 (38%), Positives = 43/97 (44%), Gaps = 3/97 (3%)
 Frame = +3

Query: 1020 QFKCNSGRCIPEHWTCDGDNDCGDYSDETHANCTNQATRPPGGCHSDEFQCRLDGLCIPL 1079
            +F+C+ G CI  +  CDG  DC D SDE  A CT   T     C         DG CI  
Sbjct: 42   EFQCDMGVCIRSYERCDGKTDCPDQSDE--AGCTPNCTNGRFTCD--------DGTCIMA 191

Query: 1080 RWRCDGDTDC---MDSSDEKSCEGVTHVCDPNVKFGC 1113
             W CDG  DC    D   +   E    VCD N +F C
Sbjct: 192  EWVCDGQYDCPRLNDDDYDDEDEMDCAVCDYNTEFAC 302

 Score = 42.0 bits (97), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 22/60 (36%), Positives = 30/60 (50%)
 Frame = +3

Query: 982  QFTCNNGRCININWRXXXXXXXXXXXXEAGCSHSCSSTQFKCNSGRCIPEHWTCDGDNDC 1041
            +F C+ G CI    R            EAGC+ +C++ +F C+ G CI   W CDG  DC
Sbjct: 42   EFQCDMGVCIRSYERCDGKTDCPDQSDEAGCTPNCTNGRFTCDDGTCIMAEWVCDGQYDC 221

 Score = 40.8 bits (94), Expect = 0.012,   Method: Compositional matrix adjust.
 Identities = 26/65 (40%), Positives = 34/65 (52%)
 Frame = +3

Query: 2821 DREFMCQNRLCIPKHFVCDHDRDCADGSDESPECEYPTCGPNEFRCANGRCLSSRQWECD 2880
            D EF C   +CI  +  CD   DC D SDE+     P C    F C +G C+ + +W CD
Sbjct: 36   DFEFQCDMGVCIRSYERCDGKTDCPDQSDEAG--CTPNCTNGRFTCDDGTCIMA-EWVCD 206

Query: 2881 GENDC 2885
            G+ DC
Sbjct: 207  GQYDC 221

 Score = 38.5 bits (88), Expect = 0.054,   Method: Compositional matrix adjust.
 Identities = 24/62 (38%), Positives = 31/62 (50%)
 Frame = +3

Query: 3339 QFVCKNDKCIPFWWKCDTEDDCGDHSDEPPDCPEFKCRPGQFQCSTGICTNPAFICDGDN 3398
            +F C    CI  + +CD + DC D SDE    P   C  G+F C  G C    ++CDG  
Sbjct: 42   EFQCDMGVCIRSYERCDGKTDCPDQSDEAGCTP--NCTNGRFTCDDGTCIMAEWVCDGQY 215

Query: 3399 DC 3400
            DC
Sbjct: 216  DC 221

 Score = 38.5 bits (88), Expect = 0.056,   Method: Compositional matrix adjust.
 Identities = 24/72 (33%), Positives = 35/72 (48%), Gaps = 1/72 (1%)
 Frame = +3

Query: 2683 YSDERDCPGVKRPRCPLNY-FACPSGRCIPMSWTCDKEDDCENGEDETHCNKFCSEAQFE 2741
            +SDER+C       C  ++ F C  G CI     CD + DC +  DE  C   C+  +F 
Sbjct: 3    WSDERNCD------CNFDFEFQCDMGVCIRSYERCDGKTDCPDQSDEAGCTPNCTNGRFT 164

Query: 2742 CQNHRCISKQWL 2753
            C +  CI  +W+
Sbjct: 165  CDDGTCIMAEWV 200

 Score = 38.5 bits (88), Expect = 0.067,   Method: Compositional matrix adjust.
 Identities = 25/62 (40%), Positives = 33/62 (53%)
 Frame = +3

Query: 3379 QFQCSTGICTNPAFICDGDNDCQDNSDEANCDIHVCLPSQFKCTNTNRCIPGIFRCNGQD 3438
            +FQC  G+C      CDG  DC D SDEA C  + C   +F C +   CI   + C+GQ 
Sbjct: 42   EFQCDMGVCIRSYERCDGKTDCPDQSDEAGCTPN-CTNGRFTC-DDGTCIMAEWVCDGQY 215

Query: 3439 NC 3440
            +C
Sbjct: 216  DC 221

 Score = 35.0 bits (79), Expect = 0.61,   Method: Compositional matrix adjust.
 Identities = 29/77 (37%), Positives = 37/77 (48%)
 Frame = +3

Query: 3404 SDEANCDIHVCLPSQFKCTNTNRCIPGIFRCNGQDNCGDGEDERDCPEVTCAPNQFQCSI 3463
            SDE NCD +     +F+C +   CI    RC+G+ +C D  DE  C    C   +F C  
Sbjct: 6    SDERNCDCN--FDFEFQC-DMGVCIRSYERCDGKTDCPDQSDEAGCTP-NCTNGRFTCD- 170

Query: 3464 TKRCIPRVWVCDRDNDC 3480
               CI   WVCD   DC
Sbjct: 171  DGTCIMAEWVCDGQYDC 221

 Score = 34.7 bits (78), Expect = 0.81,   Method: Compositional matrix adjust.
 Identities = 20/57 (35%), Positives = 27/57 (47%)
 Frame = +3

Query: 900 RFKCENNRCIPNRWLCDGDNDCGNSEDESNATCSARTCPPNQFSCASGRCIPISWTC 956
            F+C+   CI +   CDG  DC +  DE+  T     C   +F+C  G CI   W C
Sbjct: 42  EFQCDMGVCIRSYERCDGKTDCPDQSDEAGCT---PNCTNGRFTCDDGTCIMAEWVC 203

 Score = 33.9 bits (76), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 24/71 (33%), Positives = 32/71 (45%)
 Frame = +3

Query: 2522 NSSCRAQDEFECANGECISFSLTCDGVSHCKDKSDEKPSYCNSRRCKKTFRQCNNGRCVS 2581
            N  C    EF+C  G CI     CDG + C D+SDE      +  C      C++G C+ 
Sbjct: 18   NCDCNFDFEFQCDMGVCIRSYERCDGKTDCPDQSDEAGC---TPNCTNGRFTCDDGTCIM 188

Query: 2582 NMLWCNGVDDC 2592
                C+G  DC
Sbjct: 189  AEWVCDGQYDC 221

 Score = 33.9 bits (76), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 26/71 (36%), Positives = 32/71 (45%)
 Frame = +3

Query: 2610 EFRCRDGSCIGNSSRCNQFVDCEDASDEMNCSTTDCSSYFRLGVKGVLFQPCERTSLCYA 2669
            EF+C  G CI +  RC+   DC D SDE  C T +C++       G           C  
Sbjct: 42   EFQCDMGVCIRSYERCDGKTDCPDQSDEAGC-TPNCTNGRFTCDDGT----------CIM 188

Query: 2670 PSWVCDGANDC 2680
              WVCDG  DC
Sbjct: 189  AEWVCDGQYDC 221

 Score = 33.1 bits (74), Expect = 2.4,   Method: Compositional matrix adjust.
 Identities = 17/39 (43%), Positives = 21/39 (53%)
 Frame = +3

Query: 2905 CNASSQFLCSSGRCVAEALLCNGQDDCGDGSDERGCHVN 2943
            CN   +F C  G C+     C+G+ DC D SDE GC  N
Sbjct: 27   CNFDFEFQCDMGVCIRSYERCDGKTDCPDQSDEAGCTPN 143

 Score = 31.2 bits (69), Expect = 9.3,   Method: Compositional matrix adjust.
 Identities = 25/68 (36%), Positives = 33/68 (48%)
 Frame = +3

Query: 32  QFACRDQITCISKGWRCDGERDCPDGSDEAPEICPQSKAQRCPPNEHSCLGTELCVPMSR 91
           +F C D   CI    RCDG+ DCPD SDEA    P     R   ++ +C+  E       
Sbjct: 42  EFQC-DMGVCIRSYERCDGKTDCPDQSDEAGCT-PNCTNGRFTCDDGTCIMAEW------ 197

Query: 92  LCNGIQDC 99
           +C+G  DC
Sbjct: 198 VCDGQYDC 221
>20820
          Length = 1328

 Score = 53.1 bits (126), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 31/76 (40%), Positives = 42/76 (55%), Gaps = 8/76 (10%)
 Frame = -2

Query: 3580 EFSCANGR--------CIAGRWKCDGDHDCADGSDEKDCTPRCDMDQFQCKSGHCIPLRW 3631
            EFSC +G+        C+     CD   DC + +DE DC   C  ++F+C +G CIPL  
Sbjct: 238  EFSCPSGKTKCKTEPYCLDDSRFCDRIKDCDEFADETDC--NCTSEEFKCPAGPCIPLTH 65

Query: 3632 RCDADADCMDGSDEEA 3647
             CD+  DC DGSDE +
Sbjct: 64   TCDSVHDCPDGSDEAS 17

 Score = 53.1 bits (126), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 27/68 (39%), Positives = 35/68 (51%)
 Frame = -2

Query: 2661 CERTSLCYAPSWVCDGANDCGDYSDERDCPGVKRPRCPLNYFACPSGRCIPMSWTCDKED 2720
            C+    C   S  CD   DC +++DE DC       C    F CP+G CIP++ TCD   
Sbjct: 208  CKTEPYCLDDSRFCDRIKDCDEFADETDC------NCTSEEFKCPAGPCIPLTHTCDSVH 47

Query: 2721 DCENGEDE 2728
            DC +G DE
Sbjct: 46   DCPDGSDE 23

 Score = 49.3 bits (116), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 30/77 (38%), Positives = 37/77 (48%), Gaps = 1/77 (1%)
 Frame = -2

Query: 3532 CDERTCEPYQFRCKNN-RCVPGRWQCDYDNDCGDNSDEESCTPRPCSESEFSCANGRCIA 3590
            C E +C   + +CK    C+     CD   DC + +DE  C    C+  EF C  G CI 
Sbjct: 244  CPEFSCPSGKTKCKTEPYCLDDSRFCDRIKDCDEFADETDCN---CTSEEFKCPAGPCIP 74

Query: 3591 GRWKCDGDHDCADGSDE 3607
                CD  HDC DGSDE
Sbjct: 73   LTHTCDSVHDCPDGSDE 23

 Score = 48.5 bits (114), Expect = 6e-05,   Method: Compositional matrix adjust.
 Identities = 30/87 (34%), Positives = 38/87 (43%)
 Frame = -2

Query: 2770 CEGKTCGPSSFSCPGTHVCVPERWLCDGDKDCTDGADESVTAGCLYNSTCDDREFMCQNR 2829
            C   +C      C     C+ +   CD  KDC + ADE+       +  C   EF C   
Sbjct: 244  CPEFSCPSGKTKCKTEPYCLDDSRFCDRIKDCDEFADET-------DCNCTSEEFKCPAG 86

Query: 2830 LCIPKHFVCDHDRDCADGSDESPECEY 2856
             CIP    CD   DC DGSDE+  C+Y
Sbjct: 85   PCIPLTHTCDSVHDCPDGSDEASVCDY 5

 Score = 48.1 bits (113), Expect = 8e-05,   Method: Compositional matrix adjust.
 Identities = 28/95 (29%), Positives = 44/95 (46%), Gaps = 1/95 (1%)
 Frame = -2

Query: 881 LDNSDEAPALCHQHTCPSDRFKCENN-RCIPNRWLCDGDNDCGNSEDESNATCSARTCPP 939
           LDN       C + +CPS + KC+    C+ +   CD   DC    DE++  C++     
Sbjct: 274 LDNITITSGACPEFSCPSGKTKCKTEPYCLDDSRFCDRIKDCDEFADETDCNCTSE---- 107

Query: 940 NQFSCASGRCIPISWTCXXXXXXXXXXXESASCAY 974
            +F C +G CIP++ TC           E++ C Y
Sbjct: 106 -EFKCPAGPCIPLTHTCDSVHDCPDGSDEASVCDY 5

 Score = 48.1 bits (113), Expect = 9e-05,   Method: Compositional matrix adjust.
 Identities = 34/84 (40%), Positives = 43/84 (51%), Gaps = 1/84 (1%)
 Frame = -2

Query: 1015 SCSSTQFKCNSG-RCIPEHWTCDGDNDCGDYSDETHANCTNQATRPPGGCHSDEFQCRLD 1073
            SC S + KC +   C+ +   CD   DC +++DET  NCT           S+EF+C   
Sbjct: 232  SCPSGKTKCKTEPYCLDDSRFCDRIKDCDEFADETDCNCT-----------SEEFKCPA- 89

Query: 1074 GLCIPLRWRCDGDTDCMDSSDEKS 1097
            G CIPL   CD   DC D SDE S
Sbjct: 88   GPCIPLTHTCDSVHDCPDGSDEAS 17

 Score = 43.1 bits (100), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 22/61 (36%), Positives = 33/61 (54%)
 Frame = -2

Query: 2579 CVSNMLWCNGVDDCGDGSDEIPCNKTACGVGEFRCRDGSCIGNSSRCNQFVDCEDASDEM 2638
            C+ +  +C+ + DC + +DE  CN   C   EF+C  G CI  +  C+   DC D SDE 
Sbjct: 190  CLDDSRFCDRIKDCDEFADETDCN---CTSEEFKCPAGPCIPLTHTCDSVHDCPDGSDEA 20

Query: 2639 N 2639
            +
Sbjct: 19   S 17

 Score = 42.7 bits (99), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 25/86 (29%), Positives = 41/86 (47%)
 Frame = -2

Query: 27  TCSPKQFACRDQITCISKGWRCDGERDCPDGSDEAPEICPQSKAQRCPPNEHSCLGTELC 86
           +C   +  C+ +  C+     CD  +DC + +DE    C  S+  +CP           C
Sbjct: 232 SCPSGKTKCKTEPYCLDDSRFCDRIKDCDEFADETDCNC-TSEEFKCPAGP--------C 80

Query: 87  VPMSRLCNGIQDCMDGSDEGAHCREL 112
           +P++  C+ + DC DGSDE + C  L
Sbjct: 79  IPLTHTCDSVHDCPDGSDEASVCDYL 2

 Score = 41.6 bits (96), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 26/80 (32%), Positives = 36/80 (45%)
 Frame = -2

Query: 3414 CLPSQFKCTNTNRCIPGIFRCNGQDNCGDGEDERDCPEVTCAPNQFQCSITKRCIPRVWV 3473
            C   + KC     C+     C+   +C +  DE DC    C   +F+C     CIP    
Sbjct: 229  CPSGKTKCKTEPYCLDDSRFCDRIKDCDEFADETDC---NCTSEEFKCP-AGPCIPLTHT 62

Query: 3474 CDRDNDCVDGSDEPANCTQM 3493
            CD  +DC DGSDE + C  +
Sbjct: 61   CDSVHDCPDGSDEASVCDYL 2

 Score = 40.0 bits (92), Expect = 0.022,   Method: Compositional matrix adjust.
 Identities = 30/86 (34%), Positives = 36/86 (41%), Gaps = 9/86 (10%)
 Frame = -2

Query: 3332 VSNCTASQFVCKNDKCIPFWWKCDTEDDCGDHS---DEPPDCPEF------KCRPGQFQC 3382
            + N T +   C    C     KC TE  C D S   D   DC EF       C   +F+C
Sbjct: 274  LDNITITSGACPEFSCPSGKTKCKTEPYCLDDSRFCDRIKDCDEFADETDCNCTSEEFKC 95

Query: 3383 STGICTNPAFICDGDNDCQDNSDEAN 3408
              G C      CD  +DC D SDEA+
Sbjct: 94   PAGPCIPLTHTCDSVHDCPDGSDEAS 17

 Score = 39.3 bits (90), Expect = 0.036,   Method: Compositional matrix adjust.
 Identities = 50/206 (24%), Positives = 75/206 (36%), Gaps = 28/206 (13%)
 Frame = -2

Query: 3193 NGLTVDYVTERIYWADA-----------REDYIEFASLDGSNRHVVLSQDIPHIFALTLF 3241
             G  +  VTER+  +D            ++  ++F+    S   + +S     +  LT+ 
Sbjct: 589  TGHVLQIVTERLLTSDYVYMGHDLKLGDQQHCLQFSYWSTSTVRLEVS-----LIPLTVD 425

Query: 3242 EDYVYWT--DWETKSINRAHKTTGANKT--LLISTLHRPMDLHVFHALRQPDVPNHPCKV 3297
            + ++ W+     T S  R      A     L  + + R ++  V H    P V      +
Sbjct: 424  QSFLLWSMEKRHTGSWARTQAVIPAYSQGHLYYTVIGRDLNRTVLH----PMVALDNITI 257

Query: 3298 NNGGCSNLCLLSPGGGHKCACPTNFYLGGDGRTCVS-------------NCTASQFVCKN 3344
             +G C       P G  K  C T  Y   D R C               NCT+ +F C  
Sbjct: 256  TSGACPEFS--CPSG--KTKCKTEPYCLDDSRFCDRIKDCDEFADETDCNCTSEEFKCPA 89

Query: 3345 DKCIPFWWKCDTEDDCGDHSDEPPDC 3370
              CIP    CD+  DC D SDE   C
Sbjct: 88   GPCIPLTHTCDSVHDCPDGSDEASVC 11

 Score = 38.9 bits (89), Expect = 0.044,   Method: Compositional matrix adjust.
 Identities = 23/62 (37%), Positives = 31/62 (50%)
 Frame = -2

Query: 3449 CPEVTCAPNQFQCSITKRCIPRVWVCDRDNDCVDGSDEPANCTQMTCGVDEFRCKDSGRC 3508
            CPE +C   + +C     C+     CDR  DC    DE A+ T   C  +EF+C  +G C
Sbjct: 244  CPEFSCPSGKTKCKTEPYCLDDSRFCDRIKDC----DEFADETDCNCTSEEFKCP-AGPC 80

Query: 3509 IP 3510
            IP
Sbjct: 79   IP 74

 Score = 38.9 bits (89), Expect = 0.051,   Method: Compositional matrix adjust.
 Identities = 27/77 (35%), Positives = 34/77 (44%), Gaps = 8/77 (10%)
 Frame = -2

Query: 3618 QFQCKSG--------HCIPLRWRCDADADCMDGSDEEACGTGVRTCPLDEFQCNNTLCKP 3669
            +F C SG        +C+     CD   DC + +DE  C      C  +EF+C    C P
Sbjct: 238  EFSCPSGKTKCKTEPYCLDDSRFCDRIKDCDEFADETDCN-----CTSEEFKCPAGPCIP 74

Query: 3670 LAWKCDGEDDCGDNSDE 3686
            L   CD   DC D SDE
Sbjct: 73   LTHTCDSVHDCPDGSDE 23

 Score = 38.5 bits (88), Expect = 0.056,   Method: Compositional matrix adjust.
 Identities = 29/97 (29%), Positives = 41/97 (42%), Gaps = 1/97 (1%)
 Frame = -2

Query: 835 VLDTDGVTCLANPSYVPPPQCQPGEFACANN-RCIQERWKCDGDNDCLDNSDEAPALCHQ 893
            LD   +T  A P +     C  G+  C     C+ +   CD   DC + +DE       
Sbjct: 277 ALDNITITSGACPEF----SCPSGKTKCKTEPYCLDDSRFCDRIKDCDEFADETDC---- 122

Query: 894 HTCPSDRFKCENNRCIPNRWLCDGDNDCGNSEDESNA 930
             C S+ FKC    CIP    CD  +DC +  DE++ 
Sbjct: 121 -NCTSEEFKCPAGPCIPLTHTCDSVHDCPDGSDEASV 14

 Score = 37.4 bits (85), Expect = 0.13,   Method: Compositional matrix adjust.
 Identities = 30/83 (36%), Positives = 38/83 (45%), Gaps = 8/83 (9%)
 Frame = -2

Query: 2863 EFRCANGR--------CLSSRQWECDGENDCHDHSDEAPKNPHCTSPEHKCNASSQFLCS 2914
            EF C +G+        CL   ++ CD   DC + +DE   N  CTS E KC A       
Sbjct: 238  EFSCPSGKTKCKTEPYCLDDSRF-CDRIKDCDEFADETDCN--CTSEEFKCPA------- 89

Query: 2915 SGRCVAEALLCNGQDDCGDGSDE 2937
             G C+     C+   DC DGSDE
Sbjct: 88   -GPCIPLTHTCDSVHDCPDGSDE 23

 Score = 37.4 bits (85), Expect = 0.13,   Method: Compositional matrix adjust.
 Identities = 26/77 (33%), Positives = 34/77 (44%), Gaps = 8/77 (10%)
 Frame = -2

Query: 2530 EFECANGE--------CISFSLTCDGVSHCKDKSDEKPSYCNSRRCKKTFRQCNNGRCVS 2581
            EF C +G+        C+  S  CD +  C + +DE    C S   K     C  G C+ 
Sbjct: 238  EFSCPSGKTKCKTEPYCLDDSRFCDRIKDCDEFADETDCNCTSEEFK-----CPAGPCIP 74

Query: 2582 NMLWCNGVDDCGDGSDE 2598
                C+ V DC DGSDE
Sbjct: 73   LTHTCDSVHDCPDGSDE 23

 Score = 37.0 bits (84), Expect = 0.18,   Method: Compositional matrix adjust.
 Identities = 27/86 (31%), Positives = 42/86 (48%), Gaps = 1/86 (1%)
 Frame = -2

Query: 2808 SVTAGCLYNSTCDDREFMCQNR-LCIPKHFVCDHDRDCADGSDESPECEYPTCGPNEFRC 2866
            ++T+G     +C   +  C+    C+     CD  +DC + +DE+ +C    C   EF+C
Sbjct: 262  TITSGACPEFSCPSGKTKCKTEPYCLDDSRFCDRIKDCDEFADET-DCN---CTSEEFKC 95

Query: 2867 ANGRCLSSRQWECDGENDCHDHSDEA 2892
              G C+      CD  +DC D SDEA
Sbjct: 94   PAGPCIPLTH-TCDSVHDCPDGSDEA 20

 Score = 35.8 bits (81), Expect = 0.39,   Method: Compositional matrix adjust.
 Identities = 21/55 (38%), Positives = 29/55 (52%), Gaps = 8/55 (14%)
 Frame = -2

Query: 2702 FACPSGR--------CIPMSWTCDKEDDCENGEDETHCNKFCSEAQFECQNHRCI 2748
            F+CPSG+        C+  S  CD+  DC+   DET CN  C+  +F+C    CI
Sbjct: 235  FSCPSGKTKCKTEPYCLDDSRFCDRIKDCDEFADETDCN--CTSEEFKCPAGPCI 77

 Score = 35.4 bits (80), Expect = 0.56,   Method: Compositional matrix adjust.
 Identities = 17/45 (37%), Positives = 24/45 (53%), Gaps = 3/45 (6%)
 Frame = -1

Query: 2601 CNKTACGVGEFRCRDG---SCIGNSSRCNQFVDCEDASDEMNCST 2642
            C    CG  EF C      +C+  + +CN  +DC+DA DE NC+ 
Sbjct: 851  CELHGCGDEEFSCYTNGKWNCLPRAXQCNIVIDCDDAEDEKNCTA 717

 Score = 34.3 bits (77), Expect = 1.0,   Method: Compositional matrix adjust.
 Identities = 18/47 (38%), Positives = 27/47 (57%), Gaps = 2/47 (4%)
 Frame = -1

Query: 1062 GCHSDEFQCRLDGL--CIPLRWRCDGDTDCMDSSDEKSCEGVTHVCD 1106
            GC  +EF C  +G   C+P   +C+   DC D+ DEK+C   ++ CD
Sbjct: 839  GCGDEEFSCYTNGKWNCLPRAXQCNIVIDCDDAEDEKNCTAPSYKCD 699

 Score = 33.5 bits (75), Expect = 1.8,   Method: Compositional matrix adjust.
 Identities = 19/60 (31%), Positives = 27/60 (45%), Gaps = 3/60 (5%)
 Frame = -1

Query: 881 LDNSDEAPALCHQHTCPSDRFKCENN---RCIPNRWLCDGDNDCGNSEDESNATCSARTC 937
           +D+    P  C  H C  + F C  N    C+P    C+   DC ++EDE N T  +  C
Sbjct: 881 VDDPLLLPGKCELHGCGDEEFSCYTNGKWNCLPRAXQCNIVIDCDDAEDEKNCTAPSYKC 702

 Score = 33.5 bits (75), Expect = 1.9,   Method: Compositional matrix adjust.
 Identities = 15/31 (48%), Positives = 18/31 (58%)
 Frame = -2

Query: 2527 AQDEFECANGECISFSLTCDGVSHCKDKSDE 2557
              +EF+C  G CI  + TCD V  C D SDE
Sbjct: 115  TSEEFKCPAGPCIPLTHTCDSVHDCPDGSDE 23

 Score = 33.5 bits (75), Expect = 2.1,   Method: Compositional matrix adjust.
 Identities = 18/51 (35%), Positives = 24/51 (47%)
 Frame = -2

Query: 3682 DNSDENPEECARFICPPNRPFRCKNDRVCLWIGRQCDGVDNCGDGTDEEDC 3732
            DN       C  F CP  +  +CK +  CL   R CD + +C +  DE DC
Sbjct: 271  DNITITSGACPEFSCPSGKT-KCKTEPYCLDDSRFCDRIKDCDEFADETDC 122

 Score = 33.1 bits (74), Expect = 2.3,   Method: Compositional matrix adjust.
 Identities = 17/52 (32%), Positives = 26/52 (50%), Gaps = 4/52 (7%)
 Frame = -1

Query: 3407 ANCDIHVCLPSQFKCTNTNR--CIPGIFRCNGQDNCGDGEDERDC--PEVTC 3454
              C++H C   +F C    +  C+P   +CN   +C D EDE++C  P   C
Sbjct: 857  GKCELHGCGDEEFSCYTNGKWNCLPRAXQCNIVIDCDDAEDEKNCTAPSYKC 702

 Score = 33.1 bits (74), Expect = 2.5,   Method: Compositional matrix adjust.
 Identities = 27/87 (31%), Positives = 35/87 (40%), Gaps = 10/87 (11%)
 Frame = -2

Query: 3370 CPEFKCRPGQFQCSTG-ICTNPAFICDGDNDCQD---------NSDEANCDIHVCLPSQF 3419
            CPEF C  G+ +C T   C + +  CD   DC +          S+E            F
Sbjct: 244  CPEFSCPSGKTKCKTEPYCLDDSRFCDRIKDCDEFADETDCNCTSEE------------F 101

Query: 3420 KCTNTNRCIPGIFRCNGQDNCGDGEDE 3446
            KC     CIP    C+   +C DG DE
Sbjct: 100  KCP-AGPCIPLTHTCDSVHDCPDGSDE 23

 Score = 33.1 bits (74), Expect = 2.6,   Method: Compositional matrix adjust.
 Identities = 24/67 (35%), Positives = 34/67 (50%), Gaps = 3/67 (4%)
 Frame = -1

Query: 2853 ECEYPTCGPNEFRC-ANGR--CLSSRQWECDGENDCHDHSDEAPKNPHCTSPEHKCNASS 2909
            +CE   CG  EF C  NG+  CL  R  +C+   DC D  DE     +CT+P +KC+  +
Sbjct: 854  KCELHGCGDEEFSCYTNGKWNCLP-RAXQCNIVIDCDDAEDEK----NCTAPSYKCDFEN 690

Query: 2910 QFLCSSG 2916
              +   G
Sbjct: 689  XVIFGXG 669
>14158
          Length = 668

 Score = 52.4 bits (124), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 58/181 (32%), Positives = 77/181 (42%), Gaps = 20/181 (11%)
 Frame = +3

Query: 4253 GMPTCRCPTGFTGPKCTAQVCA---GYCSNNSTCTVNQ--GNQPQCRCL-PGFLGDRC-- 4304
            G  TC CP GF G +C     A     C+NNSTCTVN        C C    + GD C  
Sbjct: 24   GSYTCVCPPGFNGTRCETPYNACDNNSCANNSTCTVNPDVSRGYVCDCADSNYSGDLCNI 203

Query: 4305 --QYRQCS-GFCENFGTCQMAADGSRQCRCTVYFEGPRCE--VNKCSR--CLQGACVVNK 4357
              + + C+ G C+N G+C    + S  C C   + G  CE  +N C    C  G C  N 
Sbjct: 204  NIENKSCADGLCQNPGSCTDDVNASFTCACAPGYTGSLCESPINYCVDLPCNNGTCQSNA 383

Query: 4358 QTGDVTCNCTDGRVAPSCLTCIDHCSN-----GGSCTMNSKMMPECQCPPHMTGPRCEEQ 4412
               + TC C +G     C   ID C       GG+C ++      C C    +G  C++ 
Sbjct: 384  SLQNFTCECVEGFTGDVCDANIDDCQTNTCFYGGTC-VDGIDHWSCICAEGYSGQWCQKM 560

Query: 4413 V 4413
            V
Sbjct: 561  V 563

 Score = 41.6 bits (96), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 53/168 (31%), Positives = 70/168 (41%), Gaps = 18/168 (10%)
 Frame = +3

Query: 4204 QCFNGGSCFLN--ARRQPKCRCQ-PRYTGDKCELD----QCWE-YCHNGGTCAASPSGMP 4255
             C N  +C +N    R   C C    Y+GD C ++     C +  C N G+C    +   
Sbjct: 102  SCANNSTCTVNPDVSRGYVCDCADSNYSGDLCNINIENKSCADGLCQNPGSCTDDVNASF 281

Query: 4256 TCRCPTGFTGPKCTAQV--CAGYCSNNSTCTVNQGNQP-QCRCLPGFLGDRCQYR--QC- 4309
            TC C  G+TG  C + +  C     NN TC  N   Q   C C+ GF GD C      C 
Sbjct: 282  TCACAPGYTGSLCESPINYCVDLPCNNGTCQSNASLQNFTCECVEGFTGDVCDANIDDCQ 461

Query: 4310 SGFCENFGTCQMAADGSRQCRCTVYFEGPRCE--VNKC--SRCLQGAC 4353
            +  C   GTC    D    C C   + G  C+  VN+C  + C  G C
Sbjct: 462  TNTCFYGGTCVDGID-HWSCICAEGYSGQWCQKMVNQCDNNMCQSGVC 602
>28816
          Length = 437

 Score = 51.2 bits (121), Expect = 9e-06,   Method: Compositional matrix adjust.
 Identities = 29/67 (43%), Positives = 39/67 (58%), Gaps = 2/67 (2%)
 Frame = +3

Query: 118 RMGCQHHCVPTPSGPTCYCNSSFQLQADGKTCKDFDECS-VYGTCSQLCTNTDGSFTCGC 176
           ++ C H CV T  G  C C   +QL  D  TC+D +EC+   G C  +CTNT+GSF C C
Sbjct: 123 QLRCTHRCVNTAGGAHCTCPRGYQLADDNTTCQDTNECTNSNGGCEDVCTNTEGSFECEC 302

Query: 177 VE-GYLL 182
            + G+ L
Sbjct: 303 TKPGFRL 323

 Score = 45.8 bits (107), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 26/70 (37%), Positives = 40/70 (57%), Gaps = 1/70 (1%)
 Frame = +3

Query: 2942 VNECLSRKLSGCSQDCEDLKIGFKCRCRPGFRLKDDGRTCADLDECSTTF-PCSQLCINT 3000
            V+EC + +L  C+  C +   G  C C  G++L DD  TC D +EC+ +   C  +C NT
Sbjct: 102  VDECETGQLR-CTHRCVNTAGGAHCTCPRGYQLADDNTTCQDTNECTNSNGGCEDVCTNT 278

Query: 3001 HGSYKCLCVE 3010
             GS++C C +
Sbjct: 279  EGSFECECTK 308

 Score = 44.7 bits (104), Expect = 8e-04,   Method: Compositional matrix adjust.
 Identities = 28/76 (36%), Positives = 35/76 (46%), Gaps = 2/76 (2%)
 Frame = +3

Query: 121 CQHHCVPTPSGPTCYCNSS-FQLQADGKTCKDFDECSVYGT-CSQLCTNTDGSFTCGCVE 178
           C   C+ TP    C C    + L  +G +C D DEC      C+  C NT G   C C  
Sbjct: 6   CHQLCINTPGSYNCNCTHPLYTLNRNGYSCDDVDECETGQLRCTHRCVNTAGGAHCTCPR 185

Query: 179 GYLLQPDNRSCKAKNE 194
           GY L  DN +C+  NE
Sbjct: 186 GYQLADDNTTCQDTNE 233

 Score = 41.6 bits (96), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 22/56 (39%), Positives = 27/56 (48%), Gaps = 1/56 (1%)
 Frame = +3

Query: 3798 RCVRTEKAAYCACRSGFHTVPGQPGCQDINECLRF-GTCSQLCNNTKGGHLCSCAR 3852
            RCV T   A+C C  G+        CQD NEC    G C  +C NT+G   C C +
Sbjct: 141  RCVNTAGGAHCTCPRGYQLADDNTTCQDTNECTNSNGGCEDVCTNTEGSFECECTK 308

 Score = 40.0 bits (92), Expect = 0.020,   Method: Compositional matrix adjust.
 Identities = 23/62 (37%), Positives = 31/62 (50%), Gaps = 2/62 (3%)
 Frame = +3

Query: 2953 CSQDCEDLKIGFKCRC-RPGFRLKDDGRTCADLDECST-TFPCSQLCINTHGSYKCLCVE 3010
            C Q C +    + C C  P + L  +G +C D+DEC T    C+  C+NT G   C C  
Sbjct: 6    CHQLCINTPGSYNCNCTHPLYTLNRNGYSCDDVDECETGQLRCTHRCVNTAGGAHCTCPR 185

Query: 3011 GY 3012
            GY
Sbjct: 186  GY 191

 Score = 31.6 bits (70), Expect(2) = 0.048,   Method: Compositional matrix adjust.
 Identities = 14/38 (36%), Positives = 20/38 (52%)
 Frame = +2

Query: 2972 FRLKDDGRTCADLDECSTTFPCSQLCINTHGSYKCLCV 3009
             + + D R C D++EC     C   C N +GSY+C C 
Sbjct: 314  LQTQPDKRQCVDINECLNKSLCEGRCENLYGSYRCHCT 427

 Score = 26.2 bits (56), Expect(2) = 0.048,   Method: Compositional matrix adjust.
 Identities = 14/35 (40%), Positives = 19/35 (54%), Gaps = 1/35 (2%)
 Frame = +3

Query: 2942 VNECLSRKLSGCSQDCEDLKIGFKCRC-RPGFRLK 2975
             NEC +    GC   C + +  F+C C +PGFRL 
Sbjct: 225  TNECTNSN-GGCEDVCTNTEGSFECECTKPGFRLS 326

 Score = 33.1 bits (74), Expect = 2.7,   Method: Compositional matrix adjust.
 Identities = 21/58 (36%), Positives = 28/58 (48%), Gaps = 1/58 (1%)
 Frame = +3

Query: 1193 CSHNCSVAPGEGIVCSCPLGMELGSDNHTCQIQSYCAK-HLKCSQKCDQNKFSVKCSC 1249
            C+H C    G G  C+CP G +L  DN TCQ  + C   +  C   C   + S +C C
Sbjct: 132  CTHRCVNTAG-GAHCTCPRGYQLADDNTTCQDTNECTNSNGGCEDVCTNTEGSFECEC 302
>11992
          Length = 1209

 Score = 51.2 bits (121), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 30/74 (40%), Positives = 40/74 (54%), Gaps = 2/74 (2%)
 Frame = +2

Query: 3783 LTSCATNASMCGDEARCVRTEKAAYCACRSGFHTV-PGQPGCQDINEC-LRFGTCSQLCN 3840
            +  CA+N   C +  RCV  +    C C  G+ T   GQP C DINEC LR   C   C+
Sbjct: 68   VDECASNTHRCYNNQRCVNNDGGYRCQCPKGYRTRGIGQP-CVDINECRLRSDICQHNCS 244

Query: 3841 NTKGGHLCSCARNF 3854
            NT+G + CSC + +
Sbjct: 245  NTRGSYQCSCPKGY 286

 Score = 49.3 bits (116), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 26/69 (37%), Positives = 38/69 (55%), Gaps = 3/69 (4%)
 Frame = +2

Query: 2942 VNECLSRKLSGCSQDCEDLKIGFKCRCRPGFRLKDDGRTCADLDEC-STTFPCS--QLCI 2998
            +NEC  R    C  +C + +  ++C C  G+RL  DG +C D++EC      C   Q+C 
Sbjct: 197  INECRLRS-DICQHNCSNTRGSYQCSCPKGYRLAADGYSCTDINECWEERIQCKEEQMCF 373

Query: 2999 NTHGSYKCL 3007
            NT GSY C+
Sbjct: 374  NTRGSYSCI 400

 Score = 48.5 bits (114), Expect = 6e-05,   Method: Compositional matrix adjust.
 Identities = 29/85 (34%), Positives = 39/85 (45%), Gaps = 1/85 (1%)
 Frame = +2

Query: 111 ELRANCSRMGCQHHCVPTPSGPTCYCNSSFQLQADGKTCKDFDECSVYG-TCSQLCTNTD 169
           E  +N  R      CV    G  C C   ++ +  G+ C D +EC +    C   C+NT 
Sbjct: 74  ECASNTHRCYNNQRCVNNDGGYRCQCPKGYRTRGIGQPCVDINECRLRSDICQHNCSNTR 253

Query: 170 GSFTCGCVEGYLLQPDNRSCKAKNE 194
           GS+ C C +GY L  D  SC   NE
Sbjct: 254 GSYQCSCPKGYRLAADGYSCTDINE 328

 Score = 47.8 bits (112), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 26/75 (34%), Positives = 42/75 (56%), Gaps = 1/75 (1%)
 Frame = +2

Query: 2954 SQDCEDLKIGFKCRCRPGFRLKDDGRTCADLDECST-TFPCSQLCINTHGSYKCLCVEGY 3012
            +Q C +   G++C+C  G+R +  G+ C D++EC   +  C   C NT GSY+C C +GY
Sbjct: 107  NQRCVNNDGGYRCQCPKGYRTRGIGQPCVDINECRLRSDICQHNCSNTRGSYQCSCPKGY 286

Query: 3013 APRGGDPHSCKAVTD 3027
                 D +SC  + +
Sbjct: 287  R-LAADGYSCTDINE 328

 Score = 45.8 bits (107), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 48/164 (29%), Positives = 67/164 (40%), Gaps = 18/164 (10%)
 Frame = +2

Query: 73  CPPNEHSCLGTELCV----------PMSRLCNGI-QDCMDGSDEGAHCRELRANCSRMGC 121
           C  N H C   + CV          P      GI Q C+D ++    CR LR++     C
Sbjct: 77  CASNTHRCYNNQRCVNNDGGYRCQCPKGYRTRGIGQPCVDINE----CR-LRSDI----C 229

Query: 122 QHHCVPTPSGPTCYCNSSFQLQADGKTCKDFDEC---SVYGTCSQLCTNTDGSFTC---G 175
           QH+C  T     C C   ++L ADG +C D +EC    +     Q+C NT GS++C    
Sbjct: 230 QHNCSNTRGSYQCSCPKGYRLAADGYSCTDINECWEERIQCKEEQMCFNTRGSYSCIDIP 409

Query: 176 CVEGYLLQPDNRSCKAK-NEPVDRPPVLLIANSQNILATYLSGA 218
           C   Y+  P    C  +  +P   PP    A+        L G 
Sbjct: 410 CPTNYVRDPATNYCVLECVDPRSCPPGSKYADVIQFRTVALPGG 541

 Score = 35.8 bits (81), Expect = 0.44,   Method: Compositional matrix adjust.
 Identities = 45/182 (24%), Positives = 72/182 (39%), Gaps = 13/182 (7%)
 Frame = +2

Query: 1185 QCSLNNGGCSHNCSVAPGEGIVCSCPLGMELGSDNHTCQIQSYC-AKHLKCS--QKCDQN 1241
            +C L +  C HNCS   G    CSCP G  L +D ++C   + C  + ++C   Q C   
Sbjct: 203  ECRLRSDICQHNCSNTRG-SYQCSCPKGYRLAADGYSCTDINECWEERIQCKEEQMCFNT 379

Query: 1242 KFSVKC---SCYEGWVLEPDGESC--RSLDPFK--PFIIFSNRHEIRRIDLHKGDYSVLV 1294
            + S  C    C   +V +P    C    +DP    P   +++  + R + L  G     +
Sbjct: 380  RGSYSCIDIPCPTNYVRDPATNYCVLECVDPRSCPPGSKYADVIQFRTVALPGG-----I 544

Query: 1295 PGLRNTIALDFHLSQSALYWTDVVEDKIYRGKLLDNGALTSFEVVIQYG---LATPEGLA 1351
            P  ++ I L  +     +              LL+N    +F +  Q G   + T E L 
Sbjct: 545  PARQDLIRLTAYNHHDEMLPETTF-------TLLENDPKLTFFLRPQNGKGIVYTMERLT 703

Query: 1352 VD 1353
             D
Sbjct: 704  AD 709

 Score = 35.4 bits (80), Expect = 0.47,   Method: Compositional matrix adjust.
 Identities = 25/56 (44%), Positives = 30/56 (53%), Gaps = 4/56 (7%)
 Frame = +2

Query: 2968 CRPGFRLKDDGRTCADLDEC-STTFPC--SQLCINTHGSYKCLCVEGYAPRG-GDP 3019
            C  GF     G  C D+DEC S T  C  +Q C+N  G Y+C C +GY  RG G P
Sbjct: 23   CPRGFVRTASGE-CQDVDECASNTHRCYNNQRCVNNDGGYRCQCPKGYRTRGIGQP 187

 Score = 31.6 bits (70), Expect = 7.3,   Method: Compositional matrix adjust.
 Identities = 17/44 (38%), Positives = 23/44 (52%)
 Frame = +2

Query: 800 QQQVGTNKCRVNNGGCSSLCLATPGSRQCACAEDQVLDTDGVTC 843
           Q  V  N+CR+ +  C   C  T GS QC+C +   L  DG +C
Sbjct: 182 QPCVDINECRLRSDICQHNCSNTRGSYQCSCPKGYRLAADGYSC 313
>18708
          Length = 481

 Score = 49.3 bits (116), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 27/57 (47%), Positives = 36/57 (63%), Gaps = 7/57 (12%)
 Frame = -3

Query: 2964 FKCRCRPGFRLKDDGRTCADLDECS-TTFPCSQ---LCINTHGSYKC---LCVEGYA 3013
            ++C C  G+RLK DGR+C D+DEC   T  C Q   +C+NT G YKC    C +G+A
Sbjct: 443  YRCECPEGWRLKRDGRSCEDIDECQEKTAYCPQQDSICVNTRGHYKCPVVRCPQGFA 273

 Score = 35.4 bits (80), Expect = 0.54,   Method: Compositional matrix adjust.
 Identities = 19/54 (35%), Positives = 27/54 (50%), Gaps = 4/54 (7%)
 Frame = -3

Query: 129 PSGPTCYCNSSFQLQADGKTCKDFDECS-VYGTCSQ---LCTNTDGSFTCGCVE 178
           P    C C   ++L+ DG++C+D DEC      C Q   +C NT G + C  V 
Sbjct: 452 PGSYRCECPEGWRLKRDGRSCEDIDECQEKTAYCPQQDSICVNTRGHYKCPVVR 291
>13514
          Length = 1135

 Score = 45.1 bits (105), Expect = 6e-04,   Method: Compositional matrix adjust.
 Identities = 66/220 (30%), Positives = 83/220 (37%), Gaps = 27/220 (12%)
 Frame = -2

Query: 4221 CRCQPRYTGDKCEL--DQCWEY-CHNGGTCAASPSGMPTCRCPTGFTGPKCTAQV--C-- 4273
            C C   + G  CEL  D C  + CHNG TC         C CP  +TG  C   +  C  
Sbjct: 1116 CTCPSGFRGRNCELNIDDCVNHRCHNGSTCIDLVENY-RCECPPTYTGEFCDVDIDECDA 940

Query: 4274 --AGYCSNNSTCTVNQGNQPQCRCLPGFLGDRCQYRQ--CS-GFCENFGTCQMAADGSRQ 4328
                 C N +TC    G+   C C+ G+ GD C   +  C+   C N GTC     G   
Sbjct: 939  RYGTLCQNGATCHNTDGSF-MCVCVNGWTGDTCTINEDDCAINPCHNGGTCHDRV-GYFY 766

Query: 4329 CRCTVYFEGPRCEV------NKCSRCLQGACVVNKQTGDVTCNCTDGRVAPSCLTCIDHC 4382
            C C     G RC +      N C       C  +   G   C C  G     C   I+ C
Sbjct: 765  CECPQGKTGLRCHLDDACDSNPCY--ASAGCETSPINGVAICTCQKGWRGADCSIDINEC 592

Query: 4383 ---------SNGGSCTMNSKMMPECQCPPHMTGPRCEEQV 4413
                      +GG+C  N     +C CP   TG RCE  +
Sbjct: 591  QESTTTVVCEHGGTC-QNLNGSYQCNCPTGFTGRRCENNI 475

 Score = 40.8 bits (94), Expect = 0.014,   Method: Compositional matrix adjust.
 Identities = 58/194 (29%), Positives = 74/194 (38%), Gaps = 54/194 (27%)
 Frame = -2

Query: 4204 QCFNGGSCFLNARRQPKCRCQPRYTGDKC--ELDQC----WEYCHNGGTCAASPSGMPTC 4257
            +C NG +C ++     +C C P YTG+ C  ++D+C       C NG TC  +  G   C
Sbjct: 1050 RCHNGSTC-IDLVENYRCECPPTYTGEFCDVDIDECDARYGTLCQNGATCHNT-DGSFMC 877

Query: 4258 RCPTGFTGPKCTAQV--CA-GYCSNNSTCTVNQG----NQPQ------------------ 4292
             C  G+TG  CT     CA   C N  TC    G      PQ                  
Sbjct: 876  VCVNGWTGDTCTINEDDCAINPCHNGGTCHDRVGYFYCECPQGKTGLRCHLDDACDSNPC 697

Query: 4293 ----------------CRCLPGFLG-------DRCQYRQCSGFCENFGTCQMAADGSRQC 4329
                            C C  G+ G       + CQ    +  CE+ GTCQ   +GS QC
Sbjct: 696  YASAGCETSPINGVAICTCQKGWRGADCSIDINECQESTTTVVCEHGGTCQ-NLNGSYQC 520

Query: 4330 RCTVYFEGPRCEVN 4343
             C   F G RCE N
Sbjct: 519  NCPTGFTGRRCENN 478

 Score = 38.9 bits (89), Expect = 0.053,   Method: Compositional matrix adjust.
 Identities = 48/179 (26%), Positives = 65/179 (36%), Gaps = 10/179 (5%)
 Frame = -2

Query: 4256 TCRCPTGFTGPKCTAQV--CAGY-CSNNSTCTVNQGNQPQCRCLPGFLG-------DRCQ 4305
            TC CP+GF G  C   +  C  + C N STC ++     +C C P + G       D C 
Sbjct: 1119 TCTCPSGFRGRNCELNIDDCVNHRCHNGSTC-IDLVENYRCECPPTYTGEFCDVDIDECD 943

Query: 4306 YRQCSGFCENFGTCQMAADGSRQCRCTVYFEGPRCEVNKCSRCLQGACVVNKQTGDVTCN 4365
             R     C+N  TC    DGS  C C   + G  C +N      +  C +N         
Sbjct: 942  ARY-GTLCQNGATCH-NTDGSFMCVCVNGWTGDTCTIN------EDDCAINP-------- 811

Query: 4366 CTDGRVAPSCLTCIDHCSNGGSCTMNSKMMPECQCPPHMTGPRCEEQVVSQQQPGHMAS 4424
                            C NGG+C         C+CP   TG RC         P + ++
Sbjct: 810  ----------------CHNGGTCHDRVGYF-YCECPQGKTGLRCHLDDACDSNPCYASA 685
>14599
          Length = 1135

 Score = 44.3 bits (103), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 25/70 (35%), Positives = 36/70 (51%), Gaps = 3/70 (4%)
 Frame = -2

Query: 2956 DCEDLKIGFKCRCRPGFRLKDDGRTCADLDECSTTFPC---SQLCINTHGSYKCLCVEGY 3012
            DC      F+C CRPG+  + +G  C D+DEC+           C N +GS++C C+ GY
Sbjct: 291  DCVPSDQSFQCVCRPGY--QGNGFDCQDIDECAIEVGVCDEXARCFNVYGSFQCQCMPGY 118

Query: 3013 APRGGDPHSC 3022
                GD  +C
Sbjct: 117  Q---GDGRTC 97

 Score = 44.3 bits (103), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 29/74 (39%), Positives = 38/74 (51%), Gaps = 5/74 (6%)
 Frame = -2

Query: 121 CQHH--CVPTPSGPTCYCNSSFQLQADGKTCKDFDECSV-YGTCSQL--CTNTDGSFTCG 175
           C  H  CVP+     C C   +Q   +G  C+D DEC++  G C +   C N  GSF C 
Sbjct: 306 CHAHADCVPSDQSFQCVCRPGYQ--GNGFDCQDIDECAIEVGVCDEXARCFNVYGSFQCQ 133

Query: 176 CVEGYLLQPDNRSC 189
           C+ GY  Q D R+C
Sbjct: 132 CMPGY--QGDGRTC 97

 Score = 38.9 bits (89), Expect = 0.045,   Method: Compositional matrix adjust.
 Identities = 26/82 (31%), Positives = 36/82 (43%), Gaps = 3/82 (3%)
 Frame = -2

Query: 3786 CATNASMCGDEARCVRTEKAAYCACRSGFHTVPGQPGCQDINEC-LRFGTCSQL--CNNT 3842
            CA  +  C   A CV ++++  C CR G+        CQDI+EC +  G C +   C N 
Sbjct: 327  CAEASQTCHAHADCVPSDQSFQCVCRPGYQ--GNGFDCQDIDECAIEVGVCDEXARCFNV 154

Query: 3843 KGGHLCSCARNFMKTHNTCKAE 3864
             G   C C   +     TC  E
Sbjct: 153  YGSFQCQCMPGYQGDGRTCTRE 88
>34726
          Length = 626

 Score = 43.1 bits (100), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 34/125 (27%), Positives = 51/125 (40%), Gaps = 5/125 (4%)
 Frame = -1

Query: 2938 RGCH---VNECLSRKLSGCSQDCEDLKIGFKCRCRPGFRL-KDDGRTCADLDECS-TTFP 2992
            RGC    V+EC +      +  C +    F C C   +R+   D   C D+DEC+  T  
Sbjct: 539  RGCQCFDVDECQNSPCDSVAT-CTNTDGSFVCSCPTHYRMDTTDMTQCTDIDECAENTDN 363

Query: 2993 CSQLCINTHGSYKCLCVEGYAPRGGDPHSCKAVTDEEPFLIFANRYYLRKLNLDGSNYTL 3052
            C Q+C NT G + C CV G+        +C    +++P     N       N  G    +
Sbjct: 362  CEQVCNNTEGGFTCDCVAGFXLNATTNSTCDKDANQDPCASIXNTCSYACQNDSGXAVCV 183

Query: 3053 LKQGL 3057
              +G 
Sbjct: 182  CPKGF 168

 Score = 41.2 bits (95), Expect = 0.009,   Method: Compositional matrix adjust.
 Identities = 30/98 (30%), Positives = 44/98 (44%), Gaps = 2/98 (2%)
 Frame = -1

Query: 125 CVPTPSGPTCYCNSSFQL-QADGKTCKDFDECSV-YGTCSQLCTNTDGSFTCGCVEGYLL 182
           C  T     C C + +++   D   C D DEC+     C Q+C NT+G FTC CV G+ L
Sbjct: 476 CTNTDGSFVCSCPTHYRMDTTDMTQCTDIDECAENTDNCEQVCNNTEGGFTCDCVAGFXL 297

Query: 183 QPDNRSCKAKNEPVDRPPVLLIANSQNILATYLSGAQV 220
                S    ++  ++ P   I N+ +      SG  V
Sbjct: 296 NATTNS--TCDKDANQDPCASIXNTCSYACQNDSGXAV 189

 Score = 38.5 bits (88), Expect = 0.064,   Method: Compositional matrix adjust.
 Identities = 26/82 (31%), Positives = 39/82 (47%), Gaps = 5/82 (6%)
 Frame = -1

Query: 3791 SMCGDEARCVRTEKAAYCACRSGFHT-VPGQPGCQDINECLR-FGTCSQLCNNTKGGHLC 3848
            S C   A C  T+ +  C+C + +         C DI+EC      C Q+CNNT+GG  C
Sbjct: 500  SPCDSVATCTNTDGSFVCSCPTHYRMDTTDMTQCTDIDECAENTDNCEQVCNNTEGGFTC 321

Query: 3849 SCARNF---MKTHNTCKAEGSE 3867
             C   F     T++TC  + ++
Sbjct: 320  DCVAGFXLNATTNSTCDKDANQ 255

 Score = 33.9 bits (76), Expect = 1.7,   Method: Compositional matrix adjust.
 Identities = 26/77 (33%), Positives = 37/77 (48%), Gaps = 5/77 (6%)
 Frame = -1

Query: 2942 VNECLSRKLSGCSQDCEDLKIGFKCRCRPGFRLK-DDGRTC---ADLDECSTTF-PCSQL 2996
            ++EC +     C Q C + + GF C C  GF L      TC   A+ D C++    CS  
Sbjct: 392  IDEC-AENTDNCEQVCNNTEGGFTCDCVAGFXLNATTNSTCDKDANQDPCASIXNTCSYA 216

Query: 2997 CINTHGSYKCLCVEGYA 3013
            C N  G   C+C +G+A
Sbjct: 215  CQNDSGXAVCVCPKGFA 165

 Score = 33.5 bits (75), Expect = 1.9,   Method: Compositional matrix adjust.
 Identities = 29/90 (32%), Positives = 38/90 (42%), Gaps = 5/90 (5%)
 Frame = -1

Query: 121 CQHHCVPTPSGPTCYCNSSFQLQADGKTCKDFDE-----CSVYGTCSQLCTNTDGSFTCG 175
           C+  C  T  G TC C + F L A   +  D D       S+  TCS  C N  G   C 
Sbjct: 362 CEQVCNNTEGGFTCDCVAGFXLNATTNSTCDKDANQDPCASIXNTCSYACQNDSGXAVCV 183

Query: 176 CVEGYLLQPDNRSCKAKNEPVDRPPVLLIA 205
           C +G+ L    ++ K     V R  VL +A
Sbjct: 182 CPKGFALTTTKQAVKISMSAV-RTCVLSLA 96

 Score = 27.7 bits (60), Expect(2) = 2.2,   Method: Compositional matrix adjust.
 Identities = 15/31 (48%), Positives = 18/31 (58%)
 Frame = -3

Query: 140 FQLQADGKTCKDFDECSVYGTCSQLCTNTDG 170
           F+   +   C+D DECS    CSQ CTN DG
Sbjct: 171 FRFDYNQTGCEDIDECS-QNLCSQSCTNNDG 82

 Score = 23.9 bits (50), Expect(2) = 2.2,   Method: Compositional matrix adjust.
 Identities = 8/16 (50%), Positives = 11/16 (68%)
 Frame = -1

Query: 170 GSFTCGCVEGYLLQPD 185
           G +TC C+ GY L+ D
Sbjct: 83  GGYTCSCLPGYFLEED 36
>27664
          Length = 1281

 Score = 43.1 bits (100), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 19/39 (48%), Positives = 23/39 (58%)
 Frame = +3

Query: 3576 CSESEFSCANGRCIAGRWKCDGDHDCADGSDEKDCTPRC 3614
            CS   F CA G+C+     CDG  DC DGSDE +C  +C
Sbjct: 51   CSSGSFQCATGQCVQASRTCDGTEDCTDGSDEINCPSQC 167

 Score = 42.7 bits (99), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 23/46 (50%), Positives = 25/46 (54%)
 Frame = +3

Query: 3375 CRPGQFQCSTGICTNPAFICDGDNDCQDNSDEANCDIHVCLPSQFK 3420
            C  G FQC+TG C   +  CDG  DC D SDE NC      PSQ K
Sbjct: 51   CSSGSFQCATGQCVQASRTCDGTEDCTDGSDEINC------PSQCK 170

 Score = 39.7 bits (91), Expect = 0.030,   Method: Compositional matrix adjust.
 Identities = 17/34 (50%), Positives = 19/34 (55%)
 Frame = +3

Query: 853 PQCQPGEFACANNRCIQERWKCDGDNDCLDNSDE 886
           P C  G F CA  +C+Q    CDG  DC D SDE
Sbjct: 45  PACSSGSFQCATGQCVQASRTCDGTEDCTDGSDE 146

 Score = 38.5 bits (88), Expect = 0.061,   Method: Compositional matrix adjust.
 Identities = 20/41 (48%), Positives = 26/41 (63%)
 Frame = +3

Query: 1015 SCSSTQFKCNSGRCIPEHWTCDGDNDCGDYSDETHANCTNQ 1055
            +CSS  F+C +G+C+    TCDG  DC D SDE   NC +Q
Sbjct: 48   ACSSGSFQCATGQCVQASRTCDGTEDCTDGSDEI--NCPSQ 164

 Score = 38.1 bits (87), Expect = 0.072,   Method: Compositional matrix adjust.
 Identities = 17/41 (41%), Positives = 23/41 (56%)
 Frame = +3

Query: 2695 PRCPLNYFACPSGRCIPMSWTCDKEDDCENGEDETHCNKFC 2735
            P C    F C +G+C+  S TCD  +DC +G DE +C   C
Sbjct: 45   PACSSGSFQCATGQCVQASRTCDGTEDCTDGSDEINCPSQC 167

 Score = 38.1 bits (87), Expect = 0.084,   Method: Compositional matrix adjust.
 Identities = 18/40 (45%), Positives = 22/40 (55%)
 Frame = +3

Query: 2601 CNKTACGVGEFRCRDGSCIGNSSRCNQFVDCEDASDEMNC 2640
            C   AC  G F+C  G C+  S  C+   DC D SDE+NC
Sbjct: 36   CQLPACSSGSFQCATGQCVQASRTCDGTEDCTDGSDEINC 155

 Score = 37.4 bits (85), Expect = 0.13,   Method: Compositional matrix adjust.
 Identities = 17/37 (45%), Positives = 19/37 (51%)
 Frame = +3

Query: 3612 PRCDMDQFQCKSGHCIPLRWRCDADADCMDGSDEEAC 3648
            P C    FQC +G C+     CD   DC DGSDE  C
Sbjct: 45   PACSSGSFQCATGQCVQASRTCDGTEDCTDGSDEINC 155

 Score = 37.4 bits (85), Expect = 0.13,   Method: Compositional matrix adjust.
 Identities = 17/38 (44%), Positives = 23/38 (60%)
 Frame = +3

Query: 2854 CEYPTCGPNEFRCANGRCLSSRQWECDGENDCHDHSDE 2891
            C+ P C    F+CA G+C+ + +  CDG  DC D SDE
Sbjct: 36   CQLPACSSGSFQCATGQCVQASR-TCDGTEDCTDGSDE 146

 Score = 36.2 bits (82), Expect = 0.34,   Method: Compositional matrix adjust.
 Identities = 18/35 (51%), Positives = 21/35 (60%), Gaps = 2/35 (5%)
 Frame = +3

Query: 2531 FECANGECISFSLTCDGVSHCKDKSDEK--PSYCN 2563
            F+CA G+C+  S TCDG   C D SDE   PS C 
Sbjct: 66   FQCATGQCVQASRTCDGTEDCTDGSDEINCPSQCK 170

 Score = 35.8 bits (81), Expect = 0.39,   Method: Compositional matrix adjust.
 Identities = 16/34 (47%), Positives = 23/34 (67%)
 Frame = +3

Query: 2907 ASSQFLCSSGRCVAEALLCNGQDDCGDGSDERGC 2940
            +S  F C++G+CV  +  C+G +DC DGSDE  C
Sbjct: 54   SSGSFQCATGQCVQASRTCDGTEDCTDGSDEINC 155

 Score = 35.4 bits (80), Expect = 0.46,   Method: Compositional matrix adjust.
 Identities = 18/41 (43%), Positives = 21/41 (51%)
 Frame = +3

Query: 2561 YCNSRRCKKTFRQCNNGRCVSNMLWCNGVDDCGDGSDEIPC 2601
             C    C     QC  G+CV     C+G +DC DGSDEI C
Sbjct: 33   VCQLPACSSGSFQCATGQCVQASRTCDGTEDCTDGSDEINC 155

 Score = 33.9 bits (76), Expect = 1.7,   Method: Compositional matrix adjust.
 Identities = 21/52 (40%), Positives = 27/52 (51%), Gaps = 3/52 (5%)
 Frame = +3

Query: 3454 CAPNQFQCSITKRCIPRVWVCDRDNDCVDGSDE---PANCTQMTCGVDEFRC 3502
            C+   FQC+ T +C+     CD   DC DGSDE   P+ C  M  G +E  C
Sbjct: 51   CSSGSFQCA-TGQCVQASRTCDGTEDCTDGSDEINCPSQCKGMLRGPEETLC 203

 Score = 32.7 bits (73), Expect = 3.3,   Method: Compositional matrix adjust.
 Identities = 19/41 (46%), Positives = 22/41 (53%)
 Frame = +3

Query: 2767 AAHCEGKTCGPSSFSCPGTHVCVPERWLCDGDKDCTDGADE 2807
            A  C+   C   SF C  T  CV     CDG +DCTDG+DE
Sbjct: 27   AFVCQLPACSSGSFQC-ATGQCVQASRTCDGTEDCTDGSDE 146

 Score = 32.7 bits (73), Expect = 3.5,   Method: Compositional matrix adjust.
 Identities = 15/42 (35%), Positives = 23/42 (54%)
 Frame = +3

Query: 3409 CDIHVCLPSQFKCTNTNRCIPGIFRCNGQDNCGDGEDERDCP 3450
            C +  C    F+C  T +C+     C+G ++C DG DE +CP
Sbjct: 36   CQLPACSSGSFQCA-TGQCVQASRTCDGTEDCTDGSDEINCP 158

 Score = 32.0 bits (71), Expect = 5.3,   Method: Compositional matrix adjust.
 Identities = 14/40 (35%), Positives = 19/40 (47%)
 Frame = +3

Query: 890 LCHQHTCPSDRFKCENNRCIPNRWLCDGDNDCGNSEDESN 929
           +C    C S  F+C   +C+     CDG  DC +  DE N
Sbjct: 33  VCQLPACSSGSFQCATGQCVQASRTCDGTEDCTDGSDEIN 152
>12576
          Length = 1682

 Score = 42.4 bits (98), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 50/159 (31%), Positives = 69/159 (43%), Gaps = 21/159 (13%)
 Frame = -1

Query: 4205 CFNGGSCFLNARRQP---KCRCQPRYTGDKCE--LDQCWEY-CHNGGTC---AASPSGMP 4255
            C NGG C   A+       C C   YTG  C    D C    C NGG C     + + + 
Sbjct: 1052 CRNGGRCSSVAQGGALTFSCXCINGYTGXDCSQTADPCSSKPCKNGGMCKNVVQNGALVA 873

Query: 4256 TCRCPTGFTGPKCTAQ--VCAGY-CSNNSTCT---VNQGNQPQCRCLPGFLGDRC-QYRQ 4308
             C C  GFTG  C+ +   C+   C N +TC+          +C C  G+ G+ C Q   
Sbjct: 872  ACVCAPGFTGATCSQENNPCSSRPCKNGATCSPQLTRSSATFKCXCKSGYSGETCDQKVD 693

Query: 4309 CSGFCE-----NFGTCQMAADGSRQCRCTVYFEGPRCEV 4342
             SG C+     N  +C+  A GS +C C   ++G  CE+
Sbjct: 692  LSGACKSSPCLNGASCKPTAYGSYKCACPALYQGDNCEI 576

 Score = 40.0 bits (92), Expect = 0.024,   Method: Compositional matrix adjust.
 Identities = 71/242 (29%), Positives = 93/242 (38%), Gaps = 36/242 (14%)
 Frame = -1

Query: 4205 CFNGGSC---FLNARRQPKCRCQPRYTGDKCEL--DQCWEY-CHNGGTCAASPSGMP--- 4255
            C NGG C       +   KC C   Y G+ C+   D C    C NGG C+ +  G     
Sbjct: 1304 CRNGGVCSTEVSGGKLVSKCYCANGYEGNTCQTLADPCKPNPCKNGGLCSTTVVGGALTF 1125

Query: 4256 TCRCPTGFTGPKCTA---QVCAGYCSNNSTCT-VNQGNQP--QCRCLPGFLGDRCQYRQ- 4308
             C C  G+ G  CT       +  C N   C+ V QG      C C+ G+ G  C     
Sbjct: 1124 KCFCSAGYDGKTCTGLNDPCSSNPCRNGGRCSSVAQGGALTFSCXCINGYTGXDCSQTAD 945

Query: 4309 -CSGF-CENFGTCQ-MAADGS--RQCRCTVYFEGPRC--EVNKCSR--CLQGACV---VN 4356
             CS   C+N G C+ +  +G+    C C   F G  C  E N CS   C  GA     + 
Sbjct: 944  PCSSKPCKNGGMCKNVVQNGALVAACVCAPGFTGATCSQENNPCSSRPCKNGATCSPQLT 765

Query: 4357 KQTGDVTCNCTDGRVAPSCLTCID--------HCSNGGSCTMNSKMMPECQCPPHMTGPR 4408
            + +    C C  G    +C   +D         C NG SC   +    +C CP    G  
Sbjct: 764  RSSATFKCXCKSGYSGETCDQKVDLSGACKSSPCLNGASCKPTAYGSYKCACPALYQGDN 585

Query: 4409 CE 4410
            CE
Sbjct: 584  CE 579
>35170
          Length = 598

 Score = 42.0 bits (97), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 28/119 (23%), Positives = 54/119 (45%), Gaps = 4/119 (3%)
 Frame = +2

Query: 1753 PESKLYWISSGNHTINRCNLDGSELEVIDTMRSQ----LGKATALAIMGDKLWWADQVSE 1808
            P + LYW+ + +HTI+R  L G   +    +++     +   T L ++ D+L W+++ + 
Sbjct: 71   PSNHLYWVDTSSHTIHRLPLGGDTADRASNIQTLSMRGVHHPTGLVVVEDRLIWSEKKTG 250

Query: 1809 KMGTCNKADGSGSVVLRNSTTLVMHMKVYDESIQLEHEGTNPCSVNNGDCSQLCLPTSE 1867
             +   NK  G G   +      V  + V   +IQ  + G N C      C  +C+ + +
Sbjct: 251  AVIAANKWTGKGRRRIVKHRQGVNGLSVLHAAIQ-PNAGDNACL--RAQCHTMCVESKQ 418

 Score = 38.1 bits (87), Expect = 0.082,   Method: Compositional matrix adjust.
 Identities = 45/188 (23%), Positives = 73/188 (38%), Gaps = 1/188 (0%)
 Frame = +2

Query: 3133 NGAYRTVLVSSGLREPRALVVDVQNGYLYWTDWGDHSLIGRIGMDGSGRSIIVDTKITWP 3192
            +G  R V V   +     L +D+ + +LYW D   H+ I R+ + G              
Sbjct: 2    DGGDRQVFVQVDMLHLDHLTLDLPSNHLYWVDTSSHT-IHRLPLGGD------------- 139

Query: 3193 NGLTVDYVTERIYWADAREDYIEFASLDGSNRHVVLSQDIPHIFALTLFEDYVYWTDWET 3252
               T D           R   I+  S+ G          + H   L + ED + W++ +T
Sbjct: 140  ---TAD-----------RASNIQTLSMRG----------VHHPTGLVVVEDRLIWSEKKT 247

Query: 3253 KSINRAHKTTGANKTLLISTLHRPMDLHVFHALRQPDVPNHPCKVNNGGCSNLCLLSPG- 3311
             ++  A+K TG  +  ++        L V HA  QP+  ++ C      C  +C+ S   
Sbjct: 248  GAVIAANKWTGKGRRRIVKHRQGVNGLSVLHAAIQPNAGDNACL--RAQCHTMCVESKQW 421

Query: 3312 GGHKCACP 3319
             G KC CP
Sbjct: 422  PGFKCLCP 445

 Score = 36.6 bits (83), Expect = 0.25,   Method: Compositional matrix adjust.
 Identities = 32/128 (25%), Positives = 53/128 (41%), Gaps = 9/128 (7%)
 Frame = +2

Query: 1449 ILWIDARSDAIYSARYDG-----SGHMEVL--RGHEFLSHPFAVTLYGGEVYWTDWRTNT 1501
            + W+D  S  I+     G     + +++ L  RG   + HP  + +    + W++ +T  
Sbjct: 83   LYWVDTSSHTIHRLPLGGDTADRASNIQTLSMRG---VHHPTGLVVVEDRLIWSEKKTGA 253

Query: 1502 LAKANKWTGHNVTVVQRTNTQPFDLQVYHPSRQPMA-PNPCEANGGRGPCSHLCLINYNR 1560
            +  ANKWTG     + +       L V H + QP A  N C     R  C  +C+ +   
Sbjct: 254  VIAANKWTGKGRRRIVKHRQGVNGLSVLHAAIQPNAGDNACL----RAQCHTMCVESKQW 421

Query: 1561 T-VSCACP 1567
                C CP
Sbjct: 422  PGFKCLCP 445

 Score = 31.2 bits (69), Expect = 8.8,   Method: Compositional matrix adjust.
 Identities = 45/177 (25%), Positives = 72/177 (40%), Gaps = 9/177 (5%)
 Frame = +2

Query: 686 DGSHRDIFVTSKTVLWPNGLSLDIPAGRLYWVDAFYDRIETILLNG--TDRKIVYEGPEL 743
           DG  R +FV    +   + L+LD+P+  LYWVD     I  + L G   DR    +   +
Sbjct: 2   DGGDRQVFVQVDMLH-LDHLTLDLPSNHLYWVDTSSHTIHRLPLGGDTADRASNIQTLSM 178

Query: 744 ---NHAFGLCHHGNYLFWTEYRSGSVYRLERGVAGAPPTVTLLRSERPPIFEIRMYDAQQ 800
              +H  GL    + L W+E ++G+V    +        +   R     +    ++ A Q
Sbjct: 179 RGVHHPTGLVVVEDRLIWSEKKTGAVIAANKWTGKGRRRIVKHRQGVNGLSV--LHAAIQ 352

Query: 801 QQVGTNKCRVNNGGCSSLCLAT---PGSRQCACAEDQVLDT-DGVTCLANPSYVPPP 853
              G N C      C ++C+ +   PG + C C      D      CL +   +PPP
Sbjct: 353 PNAGDNACL--RAQCHTMCVESKQWPGFK-CLCPPRHDPDV*PTHLCLDSHHPLPPP 514
>19898
          Length = 823

 Score = 41.6 bits (96), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 21/47 (44%), Positives = 27/47 (57%)
 Frame = -2

Query: 3364 SDEPPDCPEFKCRPGQFQCSTGICTNPAFICDGDNDCQDNSDEANCD 3410
            S  P  CPE     G+  C +G+C +   +CDG  DC DNSDE +CD
Sbjct: 279  STTPAGCPE-----GKHTCPSGLCIDANNVCDGIKDCPDNSDENSCD 154

 Score = 39.3 bits (90), Expect = 0.038,   Method: Compositional matrix adjust.
 Identities = 25/54 (46%), Positives = 29/54 (53%), Gaps = 4/54 (7%)
 Frame = -2

Query: 1053 TNQATRP----PGGCHSDEFQCRLDGLCIPLRWRCDGDTDCMDSSDEKSCEGVT 1102
            + QA RP    P GC   +  C   GLCI     CDG  DC D+SDE SC+G T
Sbjct: 303  STQAPRPGSTTPAGCPEGKHTCP-SGLCIDANNVCDGIKDCPDNSDENSCDGGT 145

 Score = 38.1 bits (87), Expect = 0.073,   Method: Compositional matrix adjust.
 Identities = 19/41 (46%), Positives = 22/41 (53%)
 Frame = -2

Query: 3570 SCTPRPCSESEFSCANGRCIAGRWKCDGDHDCADGSDEKDC 3610
            S TP  C E + +C +G CI     CDG  DC D SDE  C
Sbjct: 279  STTPAGCPEGKHTCPSGLCIDANNVCDGIKDCPDNSDENSC 157

 Score = 35.8 bits (81), Expect = 0.41,   Method: Compositional matrix adjust.
 Identities = 20/51 (39%), Positives = 22/51 (43%)
 Frame = -2

Query: 836 LDTDGVTCLANPSYVPPPQCQPGEFACANNRCIQERWKCDGDNDCLDNSDE 886
           L T   T    P    P  C  G+  C +  CI     CDG  DC DNSDE
Sbjct: 318 LQTGASTQAPRPGSTTPAGCPEGKHTCPSGLCIDANNVCDGIKDCPDNSDE 166

 Score = 34.7 bits (78), Expect = 0.97,   Method: Compositional matrix adjust.
 Identities = 15/35 (42%), Positives = 24/35 (68%)
 Frame = -2

Query: 73  CPPNEHSCLGTELCVPMSRLCNGIQDCMDGSDEGA 107
           CP  +H+C  + LC+  + +C+GI+DC D SDE +
Sbjct: 261 CPEGKHTC-PSGLCIDANNVCDGIKDCPDNSDENS 160

 Score = 33.9 bits (76), Expect = 1.4,   Method: Compositional matrix adjust.
 Identities = 18/44 (40%), Positives = 21/44 (47%), Gaps = 1/44 (2%)
 Frame = -2

Query: 2690 PGVKRPR-CPLNYFACPSGRCIPMSWTCDKEDDCENGEDETHCN 2732
            PG   P  CP     CPSG CI  +  CD   DC +  DE  C+
Sbjct: 285  PGSTTPAGCPEGKHTCPSGLCIDANNVCDGIKDCPDNSDENSCD 154
>09271
          Length = 1047

 Score = 40.8 bits (94), Expect = 0.011,   Method: Compositional matrix adjust.
 Identities = 36/96 (37%), Positives = 43/96 (44%), Gaps = 11/96 (11%)
 Frame = -2

Query: 4221 CRCQPRYTGDKC--------ELDQCWEYCHNGGTCAASPSGMPTCRCPTGFTGPKCTAQV 4272
            C C+  +TG +C        E  QC   C NGG C A       CRCP G+ G +C    
Sbjct: 1025 CACRNHHTGPRCQRRLPSHPEYSQCQPACLNGGQCVA----YNRCRCPPGYRGRRCQHAF 858

Query: 4273 ---CAGYCSNNSTCTVNQGNQPQCRCLPGFLGDRCQ 4305
               C   CSN  TC    GN  +C+C  G  G RCQ
Sbjct: 857  RPDCRPPCSNGGTCL--HGN--RCQCPEGTSGHRCQ 762

 Score = 40.0 bits (92), Expect = 0.019,   Method: Compositional matrix adjust.
 Identities = 29/76 (38%), Positives = 34/76 (44%), Gaps = 3/76 (3%)
 Frame = -2

Query: 4201 CTLQCFNGGSCFLNARRQPKCRCQPRYTGDKCE---LDQCWEYCHNGGTCAASPSGMPTC 4257
            C   C NGG C    R    CRC P Y G +C+      C   C NGGTC         C
Sbjct: 953  CQPACLNGGQCVAYNR----CRCPPGYRGRRCQHAFRPDCRPPCSNGGTCLHGNR----C 798

Query: 4258 RCPTGFTGPKCTAQVC 4273
            +CP G +G +C   VC
Sbjct: 797  QCPEGTSGHRCQNSVC 750

 Score = 33.5 bits (75), Expect = 2.1,   Method: Compositional matrix adjust.
 Identities = 33/101 (32%), Positives = 43/101 (42%), Gaps = 11/101 (10%)
 Frame = -2

Query: 4256 TCRCPTGFTGPKCTAQV--------CAGYCSNNSTCTVNQGNQPQCRCLPGFLGDRCQYR 4307
             C C    TGP+C  ++        C   C N   C        +CRC PG+ G RCQ+ 
Sbjct: 1028 VCACRNHHTGPRCQRRLPSHPEYSQCQPACLNGGQCVAYN----RCRCPPGYRGRRCQHA 861

Query: 4308 ---QCSGFCENFGTCQMAADGSRQCRCTVYFEGPRCEVNKC 4345
                C   C N GTC     G+R C+C     G RC+ + C
Sbjct: 860  FRPDCRPPCSNGGTC---LHGNR-CQCPEGTSGHRCQNSVC 750
>26964
          Length = 387

 Score = 40.8 bits (94), Expect = 0.012,   Method: Compositional matrix adjust.
 Identities = 19/40 (47%), Positives = 23/40 (57%)
 Frame = -1

Query: 3374 KCRPGQFQCSTGICTNPAFICDGDNDCQDNSDEANCDIHV 3413
            +C   QFQC  G C   A +CDG +DC D SDE  CD  +
Sbjct: 120  RCDADQFQCRNGACILQAKMCDGRSDCTDESDELECDYKL 1

 Score = 40.0 bits (92), Expect = 0.019,   Method: Compositional matrix adjust.
 Identities = 20/36 (55%), Positives = 23/36 (63%)
 Frame = -1

Query: 3613 RCDMDQFQCKSGHCIPLRWRCDADADCMDGSDEEAC 3648
            RCD DQFQC++G CI     CD  +DC D SDE  C
Sbjct: 120  RCDADQFQCRNGACILQAKMCDGRSDCTDESDELEC 13

 Score = 37.0 bits (84), Expect = 0.20,   Method: Compositional matrix adjust.
 Identities = 17/40 (42%), Positives = 24/40 (60%)
 Frame = -1

Query: 2901 PEHKCNASSQFLCSSGRCVAEALLCNGQDDCGDGSDERGC 2940
            P H    + QF C +G C+ +A +C+G+ DC D SDE  C
Sbjct: 132  PAHARCDADQFQCRNGACILQAKMCDGRSDCTDESDELEC 13

 Score = 35.8 bits (81), Expect = 0.36,   Method: Compositional matrix adjust.
 Identities = 19/37 (51%), Positives = 24/37 (64%)
 Frame = -1

Query: 1063 CHSDEFQCRLDGLCIPLRWRCDGDTDCMDSSDEKSCE 1099
            C +D+FQCR +G CI     CDG +DC D SDE  C+
Sbjct: 117  CDADQFQCR-NGACILQAKMCDGRSDCTDESDELECD 10

 Score = 35.4 bits (80), Expect = 0.47,   Method: Compositional matrix adjust.
 Identities = 15/35 (42%), Positives = 22/35 (62%)
 Frame = -1

Query: 2606 CGVGEFRCRDGSCIGNSSRCNQFVDCEDASDEMNC 2640
            C   +F+CR+G+CI  +  C+   DC D SDE+ C
Sbjct: 117  CDADQFQCRNGACILQAKMCDGRSDCTDESDELEC 13

 Score = 35.0 bits (79), Expect = 0.60,   Method: Compositional matrix adjust.
 Identities = 16/29 (55%), Positives = 20/29 (68%)
 Frame = -1

Query: 2529 DEFECANGECISFSLTCDGVSHCKDKSDE 2557
            D+F+C NG CI  +  CDG S C D+SDE
Sbjct: 108  DQFQCRNGACILQAKMCDGRSDCTDESDE 22

 Score = 34.7 bits (78), Expect = 0.89,   Method: Compositional matrix adjust.
 Identities = 16/32 (50%), Positives = 21/32 (65%)
 Frame = -1

Query: 1016 CSSTQFKCNSGRCIPEHWTCDGDNDCGDYSDE 1047
            C + QF+C +G CI +   CDG +DC D SDE
Sbjct: 117  CDADQFQCRNGACILQAKMCDGRSDCTDESDE 22

 Score = 34.7 bits (78), Expect = 0.98,   Method: Compositional matrix adjust.
 Identities = 17/35 (48%), Positives = 19/35 (54%)
 Frame = -1

Query: 3576 CSESEFSCANGRCIAGRWKCDGDHDCADGSDEKDC 3610
            C   +F C NG CI     CDG  DC D SDE +C
Sbjct: 117  CDADQFQCRNGACILQAKMCDGRSDCTDESDELEC 13

 Score = 33.9 bits (76), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 17/32 (53%), Positives = 18/32 (56%)
 Frame = -1

Query: 3655 CPLDEFQCNNTLCKPLAWKCDGEDDCGDNSDE 3686
            C  D+FQC N  C   A  CDG  DC D SDE
Sbjct: 117  CDADQFQCRNGACILQAKMCDGRSDCTDESDE 22

 Score = 33.5 bits (75), Expect = 2.0,   Method: Compositional matrix adjust.
 Identities = 16/37 (43%), Positives = 20/37 (54%)
 Frame = -1

Query: 2566 RCKKTFRQCNNGRCVSNMLWCNGVDDCGDGSDEIPCN 2602
            RC     QC NG C+     C+G  DC D SDE+ C+
Sbjct: 120  RCDADQFQCRNGACILQAKMCDGRSDCTDESDELECD 10

 Score = 32.7 bits (73), Expect = 3.3,   Method: Compositional matrix adjust.
 Identities = 18/41 (43%), Positives = 25/41 (60%)
 Frame = -1

Query: 2816 NSTCDDREFMCQNRLCIPKHFVCDHDRDCADGSDESPECEY 2856
            ++ CD  +F C+N  CI +  +CD   DC D SDE  EC+Y
Sbjct: 126  HARCDADQFQCRNGACILQAKMCDGRSDCTDESDE-LECDY 7

 Score = 32.3 bits (72), Expect = 4.0,   Method: Compositional matrix adjust.
 Identities = 14/32 (43%), Positives = 20/32 (62%)
 Frame = -1

Query: 896 CPSDRFKCENNRCIPNRWLCDGDNDCGNSEDE 927
           C +D+F+C N  CI    +CDG +DC +  DE
Sbjct: 117 CDADQFQCRNGACILQAKMCDGRSDCTDESDE 22

 Score = 31.2 bits (69), Expect = 8.7,   Method: Compositional matrix adjust.
 Identities = 15/36 (41%), Positives = 22/36 (61%)
 Frame = -1

Query: 2856 YPTCGPNEFRCANGRCLSSRQWECDGENDCHDHSDE 2891
            +  C  ++F+C NG C+   +  CDG +DC D SDE
Sbjct: 126  HARCDADQFQCRNGACILQAK-MCDGRSDCTDESDE 22

 Score = 31.2 bits (69), Expect = 9.8,   Method: Compositional matrix adjust.
 Identities = 15/33 (45%), Positives = 19/33 (57%)
 Frame = -1

Query: 854 QCQPGEFACANNRCIQERWKCDGDNDCLDNSDE 886
           +C   +F C N  CI +   CDG +DC D SDE
Sbjct: 120 RCDADQFQCRNGACILQAKMCDGRSDCTDESDE 22
>22430
          Length = 497

 Score = 39.3 bits (90), Expect = 0.039,   Method: Compositional matrix adjust.
 Identities = 15/31 (48%), Positives = 21/31 (67%)
 Frame = +2

Query: 3537 CEPYQFRCKNNRCVPGRWQCDYDNDCGDNSD 3567
            C   +FRC N+RC+  R +CD  ++CGD SD
Sbjct: 218  CNQEEFRCANDRCIDKRLKCDDYDNCGDQSD 310

 Score = 38.9 bits (89), Expect = 0.042,   Method: Compositional matrix adjust.
 Identities = 17/31 (54%), Positives = 21/31 (67%)
 Frame = +2

Query: 855 CQPGEFACANNRCIQERWKCDGDNDCLDNSD 885
           C   EF CAN+RCI +R KCD  ++C D SD
Sbjct: 218 CNQEEFRCANDRCIDKRLKCDDYDNCGDQSD 310

 Score = 38.5 bits (88), Expect = 0.067,   Method: Compositional matrix adjust.
 Identities = 17/31 (54%), Positives = 20/31 (64%)
 Frame = +2

Query: 3576 CSESEFSCANGRCIAGRWKCDGDHDCADGSD 3606
            C++ EF CAN RCI  R KCD   +C D SD
Sbjct: 218  CNQEEFRCANDRCIDKRLKCDDYDNCGDQSD 310

 Score = 38.1 bits (87), Expect = 0.076,   Method: Compositional matrix adjust.
 Identities = 16/32 (50%), Positives = 20/32 (62%)
 Frame = +2

Query: 3334 NCTASQFVCKNDKCIPFWWKCDTEDDCGDHSD 3365
            +C   +F C ND+CI    KCD  D+CGD SD
Sbjct: 215  DCNQEEFRCANDRCIDKRLKCDDYDNCGDQSD 310

 Score = 35.8 bits (81), Expect = 0.43,   Method: Compositional matrix adjust.
 Identities = 14/35 (40%), Positives = 20/35 (57%)
 Frame = +2

Query: 892 HQHTCPSDRFKCENNRCIPNRWLCDGDNDCGNSED 926
           H   C  + F+C N+RCI  R  CD  ++CG+  D
Sbjct: 206 HAGDCNQEEFRCANDRCIDKRLKCDDYDNCGDQSD 310

 Score = 35.4 bits (80), Expect = 0.58,   Method: Compositional matrix adjust.
 Identities = 16/32 (50%), Positives = 20/32 (62%)
 Frame = +2

Query: 2859 CGPNEFRCANGRCLSSRQWECDGENDCHDHSD 2890
            C   EFRCAN RC+  R  +CD  ++C D SD
Sbjct: 218  CNQEEFRCANDRCIDKR-LKCDDYDNCGDQSD 310

 Score = 33.5 bits (75), Expect = 1.8,   Method: Compositional matrix adjust.
 Identities = 15/29 (51%), Positives = 18/29 (62%)
 Frame = +2

Query: 2528 QDEFECANGECISFSLTCDGVSHCKDKSD 2556
            Q+EF CAN  CI   L CD   +C D+SD
Sbjct: 224  QEEFRCANDRCIDKRLKCDDYDNCGDQSD 310

 Score = 33.1 bits (74), Expect = 2.5,   Method: Compositional matrix adjust.
 Identities = 15/41 (36%), Positives = 23/41 (56%)
 Frame = +2

Query: 1016 CSSTQFKCNSGRCIPEHWTCDGDNDCGDYSDETHANCTNQA 1056
            C+  +F+C + RCI +   CD  ++CGD SD    +  N A
Sbjct: 218  CNQEEFRCANDRCIDKRLKCDDYDNCGDQSDACLLSVGNAA 340

 Score = 32.7 bits (73), Expect = 3.9,   Method: Compositional matrix adjust.
 Identities = 17/46 (36%), Positives = 21/46 (45%)
 Frame = +2

Query: 2804 GADESVTAGCLYNSTCDDREFMCQNRLCIPKHFVCDHDRDCADGSD 2849
            GA  S+     +   C+  EF C N  CI K   CD   +C D SD
Sbjct: 173  GAGFSLVLTAFHAGDCNQEEFRCANDRCIDKRLKCDDYDNCGDQSD 310

 Score = 32.3 bits (72), Expect = 3.9,   Method: Compositional matrix adjust.
 Identities = 15/31 (48%), Positives = 18/31 (58%)
 Frame = +2

Query: 3655 CPLDEFQCNNTLCKPLAWKCDGEDDCGDNSD 3685
            C  +EF+C N  C     KCD  D+CGD SD
Sbjct: 218  CNQEEFRCANDRCIDKRLKCDDYDNCGDQSD 310

 Score = 31.6 bits (70), Expect = 8.5,   Method: Compositional matrix adjust.
 Identities = 15/27 (55%), Positives = 18/27 (66%)
 Frame = +2

Query: 3702 FRCKNDRVCLWIGRQCDGVDNCGDGTD 3728
            FRC NDR C+    +CD  DNCGD +D
Sbjct: 233  FRCANDR-CIDKRLKCDDYDNCGDQSD 310
>30893
          Length = 490

 Score = 38.5 bits (88), Expect = 0.068,   Method: Compositional matrix adjust.
 Identities = 37/108 (34%), Positives = 47/108 (43%), Gaps = 9/108 (8%)
 Frame = +2

Query: 4312 FCENFGTCQMAADGSRQCRCTVYFEGPRCE--VNKC--SRCLQGACVVNKQTGDVTCNCT 4367
             C+N GTC    + +  C C   FEG  CE  +N+C  + C  GA       G  TC C 
Sbjct: 104  LCQNGGTCHNTGN-THMCTCASGFEGSYCENDINECFSAPCQNGA-TCTDLIGRYTCTCE 277

Query: 4368 DGRVAPSCLTCIDHCS-----NGGSCTMNSKMMPECQCPPHMTGPRCE 4410
             G    +C   ID C      NGG+C  +     +C CPP   G  CE
Sbjct: 278  PGYQGLNCEYDIDECHNQPCLNGGTC-HDLVNTYKCSCPPGTQGLLCE 418

 Score = 37.0 bits (84), Expect = 0.18,   Method: Compositional matrix adjust.
 Identities = 44/133 (33%), Positives = 61/133 (45%), Gaps = 11/133 (8%)
 Frame = +2

Query: 4239 EYCHNGGTCAASPSGMPTCRCPTGFTGPKCTAQVCAGY---CSNNSTCTVNQGNQPQCRC 4295
            + C NGGTC  + +    C C +GF G  C   +   +   C N +TCT   G +  C C
Sbjct: 101  DLCQNGGTCHNTGN-THMCTCASGFEGSYCENDINECFSAPCQNGATCTDLIG-RYTCTC 274

Query: 4296 LPGFLGDRCQY--RQCSGF-CENFGTCQMAADGSRQCRCTVYFEGPRCEV--NKC---SR 4347
             PG+ G  C+Y   +C    C N GTC    + + +C C    +G  CE+  N C   S 
Sbjct: 275  EPGYQGLNCEYDIDECHNQPCLNGGTCHDLVN-TYKCSCPPGTQGLLCEMDENDCLFDST 451

Query: 4348 CLQGACVVNKQTG 4360
            C  G   V+K  G
Sbjct: 452  CHNGGTCVDKVGG 490

 Score = 32.0 bits (71), Expect = 6.3,   Method: Compositional matrix adjust.
 Identities = 22/53 (41%), Positives = 26/53 (49%), Gaps = 4/53 (7%)
 Frame = +2

Query: 4205 CFNGGSCFLNARRQPKCRCQPRYTGDKCELDQ--CW--EYCHNGGTCAASPSG 4253
            C NGG+C  +     KC C P   G  CE+D+  C     CHNGGTC     G
Sbjct: 335  CLNGGTCH-DLVNTYKCSCPPGTQGLLCEMDENDCLFDSTCHNGGTCVDKVGG 490
>13401
          Length = 497

 Score = 37.0 bits (84), Expect = 0.18,   Method: Compositional matrix adjust.
 Identities = 51/142 (35%), Positives = 69/142 (48%), Gaps = 11/142 (7%)
 Frame = -3

Query: 4202 TLQCFNGGSCFLNARRQPKCRCQPRYTGDKC--ELDQC-WEYCHNGGTCAASPSGMPTCR 4258
            T  C+NGG+C  N      C+C P +TG  C   +++C  + C N G C  + SG  TC 
Sbjct: 441  TPVCYNGGTC-TNTAGSFTCQCPPHWTGPXCGDNINECDTKPCFNAGRCQDTVSGF-TCH 268

Query: 4259 CP-TGFTGPKCTAQV--CAGY-CSNNSTCTVNQGNQPQCRCL-PGFLGDRCQ--YRQC-S 4310
            C  TGF G +C   V  C  + C N + C V+   Q  C C   G+ G+ CQ    +C S
Sbjct: 267  CSGTGFQGNRCEENVDDCVNHRCENGAPC-VDGIRQYFCNCTGTGYEGEFCQTDTDECAS 91

Query: 4311 GFCENFGTCQMAADGSRQCRCT 4332
              C+N G C    +   QC CT
Sbjct: 90   SPCKNGGNCSQGNN-KFQCTCT 28

 Score = 35.4 bits (80), Expect = 0.48,   Method: Compositional matrix adjust.
 Identities = 17/32 (53%), Positives = 21/32 (65%)
 Frame = -3

Query: 4382 CSNGGSCTMNSKMMPECQCPPHMTGPRCEEQV 4413
            C NGG+CT N+     CQCPPH TGP C + +
Sbjct: 432  CYNGGTCT-NTAGSFTCQCPPHWTGPXCGDNI 340

 Score = 33.9 bits (76), Expect = 1.4,   Method: Compositional matrix adjust.
 Identities = 62/197 (31%), Positives = 80/197 (40%), Gaps = 15/197 (7%)
 Frame = -3

Query: 4227 YTGDKCELD--QC---WEYCHNGGTCAASPSGMPTCRCPTGFTGPKCTAQVCAGYCSNNS 4281
            Y G +C+ D  +C      C+NGGTC  + +G  TC+CP  +TGP C   +         
Sbjct: 489  YDGKRCQQDVNECNATTPVCYNGGTCTNT-AGSFTCQCPPHWTGPXCGDNI--------- 340

Query: 4282 TCTVNQGNQPQCRCLPGFLGDRCQYRQCSGFCENFGTCQMAADGSRQCRCTVYFEGPRCE 4341
                      +C   P F   RCQ    SGF     TC  +  G         F+G RCE
Sbjct: 339  ---------NECDTKPCFNAGRCQDTV-SGF-----TCHCSGTG---------FQGNRCE 232

Query: 4342 --VNKC--SRCLQGACVVNKQTGDVTCNCTD-GRVAPSCLTCIDHCS-----NGGSCTMN 4391
              V+ C   RC  GA  V+       CNCT  G     C T  D C+     NGG+C+  
Sbjct: 231  ENVDDCVNHRCENGAPCVDG-IRQYFCNCTGTGYEGEFCQTDTDECASSPCKNGGNCSQG 55

Query: 4392 SKMMPECQCPPHMTGPR 4408
            +      QC    TG R
Sbjct: 54   NNKF---QCTCTDTGYR 13
>14910
          Length = 1374

 Score = 36.6 bits (83), Expect = 0.23,   Method: Compositional matrix adjust.
 Identities = 32/109 (29%), Positives = 47/109 (43%), Gaps = 10/109 (9%)
 Frame = -3

Query: 4269 TAQVCAGYCSNNSTCTVNQGNQP----QCRCLPGFLGDRC-QYRQCSGFC-----ENFGT 4318
            T  V  G C N   C+V + +      +C C  G+ G+ C Q    SG C     +N G+
Sbjct: 385  TRSVRNGPCKNGGECSVQKTDAGLFLFKCTCAEGYSGETCDQTVDTSGACSSRPCQNGGS 206

Query: 4319 CQMAADGSRQCRCTVYFEGPRCEVNKCSRCLQGACVVNKQTGDVTCNCT 4367
            C+  + GS +C C   ++G  CE+         +  VN   GD    CT
Sbjct: 205  CKPTSYGSYKCTCPALYQGDSCEIK--------SAWVNSPCGDAEAGCT 83

 Score = 32.7 bits (73), Expect = 3.8,   Method: Compositional matrix adjust.
 Identities = 17/41 (41%), Positives = 21/41 (51%), Gaps = 1/41 (2%)
 Frame = -3

Query: 4199 GTCTLQ-CFNGGSCFLNARRQPKCRCQPRYTGDKCELDQCW 4238
            G C+ + C NGGSC   +    KC C   Y GD CE+   W
Sbjct: 244  GACSSRPCQNGGSCKPTSYGSYKCTCPALYQGDSCEIKSAW 122

 Score = 32.3 bits (72), Expect = 4.2,   Method: Compositional matrix adjust.
 Identities = 24/76 (31%), Positives = 31/76 (40%), Gaps = 12/76 (15%)
 Frame = -3

Query: 4205 CFNGGSCFLNARRQP----KCRCQPRYTGDKCELDQCWEY--------CHNGGTCAASPS 4252
            C NGG C +          KC C   Y+G+ C  DQ  +         C NGG+C  +  
Sbjct: 361  CKNGGECSVQKTDAGLFLFKCTCAEGYSGETC--DQTVDTSGACSSRPCQNGGSCKPTSY 188

Query: 4253 GMPTCRCPTGFTGPKC 4268
            G   C CP  + G  C
Sbjct: 187  GSYKCTCPALYQGDSC 140
>11667
          Length = 1227

 Score = 36.2 bits (82), Expect = 0.29,   Method: Compositional matrix adjust.
 Identities = 25/54 (46%), Positives = 30/54 (55%), Gaps = 4/54 (7%)
 Frame = +3

Query: 2967 RCRPGFRLKDDGRTCADLDECSTTFP-CS---QLCINTHGSYKCLCVEGYAPRG 3016
            +C  G+ L+D    C D+DECS     CS   Q+C NT GSYKC C  GY   G
Sbjct: 648  KCSAGYYLQDG--KCLDMDECSEDGQLCSDEGQVCENTVGSYKCECQPGYNKIG 803

 Score = 33.5 bits (75), Expect = 2.0,   Method: Compositional matrix adjust.
 Identities = 29/59 (49%), Positives = 34/59 (57%), Gaps = 6/59 (10%)
 Frame = +3

Query: 128 TPSGP--TCYCNSSFQLQADGKTCKDFDECSVYGT-CS---QLCTNTDGSFTCGCVEGY 180
           T SGP     C++ + LQ DGK C D DECS  G  CS   Q+C NT GS+ C C  GY
Sbjct: 621 TGSGPDHCVKCSAGYYLQ-DGK-CLDMDECSEDGQLCSDEGQVCENTVGSYKCECQPGY 791
>09839
          Length = 1599

 Score = 35.8 bits (81), Expect = 0.38,   Method: Compositional matrix adjust.
 Identities = 26/76 (34%), Positives = 35/76 (46%), Gaps = 5/76 (6%)
 Frame = +1

Query: 4271 QVCAGYCSNNSTCTVNQGNQPQCRCLPGFLGDRCQYRQCSGFCE-NFGTCQMAADGSRQ- 4328
            Q  A  CS N+ C+V+     QC C   + GD      C+  C+   G CQ  AD  +  
Sbjct: 898  QTSANTCSTNAGCSVDNTGTVQCSCNANYQGDG---TTCTHVCDVAGGYCQNGADCVKNL 1068

Query: 4329 ---CRCTVYFEGPRCE 4341
               C C  ++ GPRCE
Sbjct: 1069 AAPCVCKQFYSGPRCE 1116
>05519
          Length = 1164

 Score = 35.4 bits (80), Expect = 0.58,   Method: Compositional matrix adjust.
 Identities = 32/107 (29%), Positives = 46/107 (42%), Gaps = 11/107 (10%)
 Frame = -2

Query: 4272 VCAGY-CSNNSTCTVNQGNQP----QCRCLPGFLGDRC-QYRQCSGFC-----ENFGTCQ 4320
            VCA   C N + C+V          +C C  G+ G+ C Q    SG C     +N G+C+
Sbjct: 305  VCASSPCKNGAKCSVQVTRARLSLFKCTCAKGYSGETCDQSVDTSGACASRPCQNGGSCK 126

Query: 4321 MAADGSRQCRCTVYFEGPRCEVNKCSRCLQGACVVNKQTGDVTCNCT 4367
              + GS +C C   ++G  CE+         +  VN   GD    CT
Sbjct: 125  PTSYGSFKCTCPALYQGDSCEIK--------SAWVNSPCGDTGVACT 9

 Score = 34.3 bits (77), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 24/76 (31%), Positives = 31/76 (40%), Gaps = 12/76 (15%)
 Frame = -2

Query: 4205 CFNGGSCFLNARRQP----KCRCQPRYTGDKCELDQCWEY--------CHNGGTCAASPS 4252
            C NG  C +   R      KC C   Y+G+ C  DQ  +         C NGG+C  +  
Sbjct: 287  CKNGAKCSVQVTRARLSLFKCTCAKGYSGETC--DQSVDTSGACASRPCQNGGSCKPTSY 114

Query: 4253 GMPTCRCPTGFTGPKC 4268
            G   C CP  + G  C
Sbjct: 113  GSFKCTCPALYQGDSC 66

 Score = 33.1 bits (74), Expect = 2.9,   Method: Compositional matrix adjust.
 Identities = 15/34 (44%), Positives = 17/34 (50%)
 Frame = -2

Query: 4205 CFNGGSCFLNARRQPKCRCQPRYTGDKCELDQCW 4238
            C NGGSC   +    KC C   Y GD CE+   W
Sbjct: 149  CQNGGSCKPTSYGSFKCTCPALYQGDSCEIKSAW 48
>26257
          Length = 466

 Score = 35.0 bits (79), Expect = 0.62,   Method: Compositional matrix adjust.
 Identities = 30/96 (31%), Positives = 44/96 (45%), Gaps = 9/96 (9%)
 Frame = -2

Query: 3783 LTSCATNASMCGDEARCVRTEKAAYCACRSGFHTV----PGQPGCQDINECLRFG---TC 3835
            +  CA   S C   + C+      +C C  GFH+          C D+NEC+  G   TC
Sbjct: 336  IDECALGLSACRGNSVCINEPGWYHCDCLQGFHSAWPDNHFGSLCLDVNECVGEGEGHTC 157

Query: 3836 --SQLCNNTKGGHLCSCARNFMKTHNTCKAEGSEYQ 3869
              S  C NT+GG+ C C       H +C  +G+E++
Sbjct: 156  HPSTRCVNTEGGYSCQCGARENCLH-SCIFQGAEHK 52

 Score = 31.6 bits (70), Expect = 8.2,   Method: Compositional matrix adjust.
 Identities = 26/69 (37%), Positives = 32/69 (46%), Gaps = 5/69 (7%)
 Frame = -2

Query: 4236 QCWEYCHNGGTCAASPSGMPTCRCPTGFTGPKCTAQV--CA---GYCSNNSTCTVNQGNQ 4290
            +C   C NGG C     G  TC+C  G+ GP C   +  CA     C  NS C +N+   
Sbjct: 432  ECHGDCLNGGKCI----GPNTCQCRHGYIGPNCELDIDECALGLSACRGNSVC-INEPGW 268

Query: 4291 PQCRCLPGF 4299
              C CL GF
Sbjct: 267  YHCDCLQGF 241
>21089
          Length = 434

 Score = 34.3 bits (77), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 13/29 (44%), Positives = 19/29 (65%)
 Frame = -3

Query: 32  QFACRDQITCISKGWRCDGERDCPDGSDE 60
            F C +++ C+S+  RCD E  C DG+DE
Sbjct: 360 MFMCENKLMCVSQNLRCDEEPHCSDGTDE 274

 Score = 32.0 bits (71), Expect = 5.5,   Method: Compositional matrix adjust.
 Identities = 13/28 (46%), Positives = 21/28 (75%), Gaps = 1/28 (3%)
 Frame = -3

Query: 2824 FMCQNRL-CIPKHFVCDHDRDCADGSDE 2850
            FMC+N+L C+ ++  CD +  C+DG+DE
Sbjct: 357  FMCENKLMCVSQNLRCDEEPHCSDGTDE 274
>03773
          Length = 1046

 Score = 34.3 bits (77), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 21/61 (34%), Positives = 31/61 (50%), Gaps = 4/61 (6%)
 Frame = +2

Query: 3805 AAYCACRSGFHTVPGQPGCQDINECLRFGTCSQL----CNNTKGGHLCSCARNFMKTHNT 3860
              +C C +G++   G     DINEC    TC+ +    CNNT GG++C+C   F  +   
Sbjct: 197  TGFCNCTTGWN---GTDCATDINECEDSATCASISNSHCNNTLGGYVCACDDGFSSSGGM 367

Query: 3861 C 3861
            C
Sbjct: 368  C 370

 Score = 33.5 bits (75), Expect = 1.8,   Method: Compositional matrix adjust.
 Identities = 17/68 (25%), Positives = 32/68 (47%), Gaps = 5/68 (7%)
 Frame = +2

Query: 2955 QDCEDLKIGFKCRCRPGFRLKDDGRTCADLDEC-----STTFPCSQLCINTHGSYKCLCV 3009
            + C D   G+ C C  G+        C +++EC     +T    +++C+++ GS+ C C 
Sbjct: 560  ETCRDFDGGYSCDCVSGYERPSPSDNCTNINECLYASLNTCNMTTEICVDSDGSFGCECK 739

Query: 3010 EGYAPRGG 3017
             G+    G
Sbjct: 740  SGFNSTSG 763

 Score = 33.5 bits (75), Expect = 2.1,   Method: Compositional matrix adjust.
 Identities = 24/78 (30%), Positives = 39/78 (50%), Gaps = 6/78 (7%)
 Frame = +2

Query: 2942 VNECLSRKLSGCS--QDCEDLKIGFKCRCRPGFRLKDDGRTCADLDECSTT----FPCSQ 2995
            V+EC    L+ CS  +DC +    + C+C+  + L +    C D +ECS +        +
Sbjct: 776  VDECTDPALNTCSDREDCVNSVGSYTCQCKSTYVLVN--XVCTDFNECSDSSLNNCTSKE 949

Query: 2996 LCINTHGSYKCLCVEGYA 3013
             C++  G Y+C C  GYA
Sbjct: 950  NCVDIIGGYRCDCKTGYA 1003

 Score = 32.0 bits (71), Expect = 5.9,   Method: Compositional matrix adjust.
 Identities = 23/64 (35%), Positives = 33/64 (51%), Gaps = 5/64 (7%)
 Frame = +2

Query: 2959 DLKIGFKCRCRPGFRLKDDGRTCA-DLDECSTTFPCSQL----CINTHGSYKCLCVEGYA 3013
            D   GF C C  G+    +G  CA D++EC  +  C+ +    C NT G Y C C +G++
Sbjct: 188  DAVTGF-CNCTTGW----NGTDCATDINECEDSATCASISNSHCNNTLGGYVCACDDGFS 352

Query: 3014 PRGG 3017
              GG
Sbjct: 353  SSGG 364

 Score = 31.6 bits (70), Expect = 6.8,   Method: Compositional matrix adjust.
 Identities = 26/84 (30%), Positives = 36/84 (42%), Gaps = 7/84 (8%)
 Frame = +2

Query: 3786 CATNASMC--GDEARCVRTEKAAYCACRSGFHTVPGQPGCQDINECL--RFGTC---SQL 3838
            CA NAS+C       C   +    C C SG+        C +INECL     TC   +++
Sbjct: 521  CAVNASICQTNPHETCRDFDGGYSCDCVSGYERPSPSDNCTNINECLYASLNTCNMTTEI 700

Query: 3839 CNNTKGGHLCSCARNFMKTHNTCK 3862
            C ++ G   C C   F  T  +C 
Sbjct: 701  CVDSDGSFGCECKSGFNSTSGSCT 772
>12186
          Length = 580

 Score = 33.9 bits (76), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 18/49 (36%), Positives = 25/49 (51%), Gaps = 7/49 (14%)
 Frame = +3

Query: 887 APALCHQHTCPSD------RFKCEN-NRCIPNRWLCDGDNDCGNSEDES 928
            PA C  H+ P D       ++C N + C+  R LCDG   C + +DES
Sbjct: 177 VPAACQSHSPPKDLCTDKDAYRCHNTDECVEERQLCDGVTQCTHGDDES 323

 Score = 32.7 bits (73), Expect = 3.3,   Method: Compositional matrix adjust.
 Identities = 16/30 (53%), Positives = 18/30 (60%)
 Frame = +3

Query: 2779 SFSCPGTHVCVPERWLCDGDKDCTDGADES 2808
            ++ C  T  CV ER LCDG   CT G DES
Sbjct: 234  AYRCHNTDECVEERQLCDGVTQCTHGDDES 323
>00070
          Length = 1809

 Score = 33.5 bits (75), Expect = 1.9,   Method: Compositional matrix adjust.
 Identities = 26/83 (31%), Positives = 41/83 (49%), Gaps = 11/83 (13%)
 Frame = +1

Query: 4272 VCAGY-CSNNSTCTVN----QGNQPQCRCLPGFLGDRC-QYRQCSGFC-----ENFGTCQ 4320
            VCA   C N + C+V     + +  +C C  G+ G+ C Q    SG C     +N G+C+
Sbjct: 142  VCASSPCKNGAKCSVQVTRARLSLFKCTCAKGYSGETCDQSVDTSGACASRPCQNGGSCK 321

Query: 4321 MAADGSRQCRCTVYFEGPRCEVN 4343
              + GS +C C   ++G  CE+ 
Sbjct: 322  PTSYGSFKCTCPALYQGDSCEIK 390

 Score = 32.0 bits (71), Expect = 5.2,   Method: Compositional matrix adjust.
 Identities = 23/74 (31%), Positives = 30/74 (40%), Gaps = 10/74 (13%)
 Frame = +1

Query: 4205 CFNGGSCFLNARRQP----KCRCQPRYTGDKCELD-----QCWEY-CHNGGTCAASPSGM 4254
            C NG  C +   R      KC C   Y+G+ C+        C    C NGG+C  +  G 
Sbjct: 160  CKNGAKCSVQVTRARLSLFKCTCAKGYSGETCDQSVDTSGACASRPCQNGGSCKPTSYGS 339

Query: 4255 PTCRCPTGFTGPKC 4268
              C CP  + G  C
Sbjct: 340  FKCTCPALYQGDSC 381

 Score = 32.0 bits (71), Expect = 6.2,   Method: Compositional matrix adjust.
 Identities = 15/34 (44%), Positives = 17/34 (50%)
 Frame = +1

Query: 4205 CFNGGSCFLNARRQPKCRCQPRYTGDKCELDQCW 4238
            C NGGSC   +    KC C   Y GD CE+   W
Sbjct: 298  CQNGGSCKPTSYGSFKCTCPALYQGDSCEIKSAW 399
>37574
          Length = 433

 Score = 32.7 bits (73), Expect = 3.1,   Method: Compositional matrix adjust.
 Identities = 27/87 (31%), Positives = 35/87 (40%)
 Frame = -3

Query: 4261 TGFTGPKCTAQVCAGYCSNNSTCTVNQGNQPQCRCLPGFLGDRCQYRQCSGFCENFGTCQ 4320
            T FTGP C  +VC         C        +C C  G+ G  C   QC   C   G C 
Sbjct: 263  TAFTGPDCETEVC------RLVCVHGHCRNQRCVCAQGWTGALCDQLQCDRRCHAHGFC- 105

Query: 4321 MAADGSRQCRCTVYFEGPRCEVNKCSR 4347
              ++GS  C C   + G  C +N C +
Sbjct: 104  --SNGS--CVCDKGWNGKHCTINGCPK 36
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|33859530|ref|NP_034098.1| crystallin, zeta [Mus
musculus]
         (331 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

25131                                                                 167   4e-42
18797                                                                  53   1e-07
09080                                                                  41   8e-04
00104                                                                  33   0.20 
03060                                                                  28   3.9  
>25131
          Length = 982

 Score =  167 bits (424), Expect = 4e-42,   Method: Compositional matrix adjust.
 Identities = 90/183 (49%), Positives = 117/183 (63%)
 Frame = +3

Query: 147 RAGESVLVHGASGGVGLATCQIARAHGLKVLGTAGSEEGKKLVLQNGAHEVFNHKEANYI 206
           + GE+VLVHGASG VGLA  QIA+A GL+VLGTAG+  G  LV  NGA +VFNH+E  Y 
Sbjct: 246 KPGETVLVHGASGAVGLACVQIAKAMGLRVLGTAGTPXGLDLVKTNGASDVFNHREEGYN 425

Query: 207 DKIKMSVGDKDKGVDVIIEMLANENLSNDLKLLSHXXXXXXXXXXXPIEINPRDTMAKET 266
             I  + G +  G +VIIEML+N NL  DL+++              +EINPR  M KE 
Sbjct: 426 ANIMAATGGE--GPNVIIEMLSNVNLQRDLEMVKFQGRIVVIGCRGTVEINPRLMMGKEL 599

Query: 267 SIIGVSLSSSTKEEFQQFAGLLQAGIEKGWVKPVIGSEYPLEKAAQAHEDIIHGSGKTGK 326
            + GV L SST E++Q+    + AG E GW+KP +G EY LE+A  AH DII+ SG  GK
Sbjct: 600 QVNGVMLPSSTPEQWQEAHAFMFAGAECGWLKPCVGKEYALEEAPVAHTDIINNSGAAGK 779

Query: 327 MIL 329
           +++
Sbjct: 780 LVI 788

 Score = 93.6 bits (231), Expect = 1e-19,   Method: Compositional matrix adjust.
 Identities = 56/122 (45%), Positives = 74/122 (60%), Gaps = 1/122 (0%)
 Frame = +2

Query: 65  LPYTPGSDVAGIIESVGDKVSAFKKGDRVFCYSTVSGGYAEFALAADDTIYPLPETLNFR 124
           LPYTPGSD AG++ESVG KV  FKKGDR +   +V+G Y E+A++       L + L+F 
Sbjct: 2   LPYTPGSDAAGVVESVGXKVKDFKKGDRAYTIRSVTGTYGEYAVSEVVHTARLSDKLSFS 181

Query: 125 QGAALGIPYFTACRALFHSAR-ARAGESVLVHGASGGVGLATCQIARAHGLKVLGTAGSE 183
           QGAALG+PY+TA RAL   A+ AR   S      SGG  L + +   +HG    G +G+ 
Sbjct: 182 QGAALGVPYYTAYRALVTKAK*ARRNRSCPWSKWSGGSRLRSDR--*SHGAAGSGHSGNX 355

Query: 184 EG 185
            G
Sbjct: 356 PG 361
>18797
          Length = 1159

 Score = 53.1 bits (126), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 52/190 (27%), Positives = 82/190 (43%), Gaps = 10/190 (5%)
 Frame = -1

Query: 51  ETYIRSGAYSRKPALPYTPGSDVAGIIESVGDKVSAFKKGDRV---FCYSTVSGGYAEFA 107
           +T +      R P      G DV+GI++ VG +VS  K+GD V       T + G  EF 
Sbjct: 991 DTLLYKNVTDRLPV-----GRDVSGIVKDVGSRVSTVKEGDEVVGILPLDTTTSGCGEFC 827

Query: 108 LAADDTIYPLPETLNFRQGAALGIPYFTACRALFHSARARAGESVLVHGASGGVGLATCQ 167
           +  +  +   P  ++  + AA+      A  AL +     AG+SVL+   +   G    Q
Sbjct: 826 IFREFDVAKKPHRVSHEEAAAVIGDAVRAYTALHYHTHVCAGDSVLIMDGATHAGSVAVQ 647

Query: 168 IARAHGLKVLGTAGSEEGKKLVLQNGAHEVFNHKEANYIDKIKMSVGDKDK---GVDVII 224
           +A   G KV+ T  S   K+  L +    V    E N    + +S   ++    GVD I+
Sbjct: 646 MALLWGAKVMTTYSSVPEKQF-LDSFHPTVAQTMELNQRSTLLVSTVMEETGGIGVDCIV 470

Query: 225 E----MLANE 230
           +    M +NE
Sbjct: 469 DNGVRMFSNE 440
>09080
          Length = 1659

 Score = 40.8 bits (94), Expect = 8e-04,   Method: Compositional matrix adjust.
 Identities = 28/77 (36%), Positives = 45/77 (58%), Gaps = 1/77 (1%)
 Frame = +2

Query: 22  LKLQSDVVVPVPQSHQVLIKVHACGVNPVETYIRSGAYSRKPALPYTPGSDVAGIIESVG 81
           L +++  V P P++ +V IK+ A GV   + Y  +G    + A P   G + AGI+ES+G
Sbjct: 50  LTIETIQVAP-PKAGEVRIKILATGVCHTDAYTLNG-LDPEGAFPVVLGHEGAGIVESIG 223

Query: 82  DKVSAFKKGDRVF-CYS 97
           + V++  KGD V  CY+
Sbjct: 224 EGVTSVAKGDLVIPCYT 274
>00104
          Length = 1480

 Score = 32.7 bits (73), Expect = 0.20,   Method: Compositional matrix adjust.
 Identities = 23/76 (30%), Positives = 38/76 (50%), Gaps = 4/76 (5%)
 Frame = -2

Query: 167  QIARAHGLKVLGTAGSEEGKKLVLQNGAHEVFNHKEANYIDKIKMSVGDKDKGVDVIIEM 226
            QIA+  G  V+G+AGS+     + + G   VFN+KE    + +K    +   G+D+  + 
Sbjct: 1479 QIAKVKGCTVIGSAGSQAKCDWLKELGFDHVFNYKETTVDEALKKFAPN---GIDIHFDN 1309

Query: 227  LANEN----LSNDLKL 238
            +  E     +SN LK 
Sbjct: 1308 VGGEFSYTVMSNHLKF 1261
>03060
          Length = 1893

 Score = 28.5 bits (62), Expect = 3.9,   Method: Compositional matrix adjust.
 Identities = 17/41 (41%), Positives = 23/41 (56%), Gaps = 4/41 (9%)
 Frame = -1

Query: 141  FHSARARA----GESVLVHGASGGVGLATCQIARAHGLKVL 177
            F   R RA    G+ VLV GAS G+G A  ++   HG +V+
Sbjct: 1725 FIKLRTRAADIQGKVVLVTGASSGLGKACAKVFHQHGCQVI 1603
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|57634518|ref|NP_001009818.1| septin 11 [Mus musculus]
         (429 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

14677                                                                 130   4e-42
14132                                                                 138   5e-33
22078                                                                  68   9e-12
29788                                                                  67   2e-11
34156                                                                  59   5e-09
38061                                                                  53   3e-07
>14677
          Length = 378

 Score =  130 bits (327), Expect(2) = 4e-42,   Method: Compositional matrix adjust.
 Identities = 59/76 (77%), Positives = 68/76 (89%)
 Frame = -1

Query: 78  VRLKARSYELQESNVRLKLTIVDTVGFGDQINKDDSYKPIVEYIDAQFEAYLQEELKIKR 137
           V+LKA +Y+L E NVRLKLT VDT GFGDQINK DS+KPIV+YIDAQF+AYLQEELKIKR
Sbjct: 228 VKLKAHTYDLTEKNVRLKLTTVDTTGFGDQINKADSWKPIVDYIDAQFDAYLQEELKIKR 49

Query: 138 SLFNYHDTRIHACLYF 153
            L +YHD+R+HACLYF
Sbjct: 48  MLHSYHDSRVHACLYF 1

 Score = 59.3 bits (142), Expect(2) = 4e-42,   Method: Composition-based stats.
 Identities = 28/54 (51%), Positives = 36/54 (66%)
 Frame = -3

Query: 29  DQLVNKSTSQGFCFNILCVGETGIGKSTLMDTLFNTKFESDPATHNEPGVRLKA 82
           DQLV   + +        +GETGIGKSTLMDTLFNT F+S P++H+ PG + K 
Sbjct: 376 DQLVTSLSLKASASTFFVLGETGIGKSTLMDTLFNTNFDSTPSSHDLPGRQTKG 215
>14132
          Length = 422

 Score =  138 bits (347), Expect = 5e-33,   Method: Compositional matrix adjust.
 Identities = 65/139 (46%), Positives = 97/139 (69%), Gaps = 3/139 (2%)
 Frame = -2

Query: 104 FGDQINKDDSYKPIVEYIDAQFEAYLQEELKIKRSLFNYHDTRIHACLYFIAPTGHSLKS 163
           FGD ++  + ++PI +YID+++E YL  E ++ R++    DTR+H CLYFIAPTGH LK 
Sbjct: 421 FGDAVDNSNCWQPITDYIDSKYEEYLNAESRVNRTVMP--DTRVHCCLYFIAPTGHGLKP 248

Query: 164 LDLVTMKKLDSKVNIIPIIAKADTIAKNELHKFKSKIMSELVSNGVQIYQFP-TDEETVA 222
           LD+  MK+L  KVNIIP++AKADT+  +E  +FK  I++E+  + ++IY+FP  D+E   
Sbjct: 247 LDVEFMKRLHDKVNIIPLVAKADTLTPDECREFKKTILNEIAQHKIKIYEFPDCDDEEEM 68

Query: 223 EINATMSV--HLPFAVVGS 239
           +I   + V   +PFAVVGS
Sbjct: 67  KIQKRLRVSDRVPFAVVGS 11
>22078
          Length = 417

 Score = 67.8 bits (164), Expect = 9e-12,   Method: Compositional matrix adjust.
 Identities = 25/48 (52%), Positives = 38/48 (79%)
 Frame = +3

Query: 251 KARQYPWGVVQVENENHCDFVKLREMLIRVNMEDLREQTHTRHYELYR 298
           + R YPWG+V+V+N +HCDF++LR+MLI  +M+DL++ T   HYE +R
Sbjct: 3   RGRAYPWGIVEVDNXSHCDFIRLRQMLISTHMQDLKDVTSDVHYENFR 146
>29788
          Length = 687

 Score = 66.6 bits (161), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 39/96 (40%), Positives = 57/96 (59%), Gaps = 4/96 (4%)
 Frame = +3

Query: 256 PWGVVQVENENHCDFVKLREMLIRVNMEDLREQTHTRHYELYRRCKLEEMGFKDTDPDSK 315
           PWG+V+VEN  H DF+ LR MLIR +M+DL++ T+  HYE +R  KL       T+   K
Sbjct: 3   PWGIVEVENLEHNDFIALRNMLIRTHMQDLKDVTNNVHYENFRYNKL---APSTTEGKVK 173

Query: 316 PFSLQE----TYEAKRNEFLGELQKKEEEMRQMFVM 347
           P +L +        +R E + +++K E EM Q+F M
Sbjct: 174 PGALAKDPLSQMAEERQEHMVKMKKMEAEMEQVFEM 281
>34156
          Length = 348

 Score = 58.5 bits (140), Expect = 5e-09,   Method: Composition-based stats.
 Identities = 31/79 (39%), Positives = 51/79 (64%), Gaps = 5/79 (6%)
 Frame = -1

Query: 28  PDQLVNKSTSQGFCFNILCVGETGIGKSTLMDTLFNTKFESD---PATHN--EPGVRLKA 82
           P Q+  KS  +GF F ++ VGE+G+GKSTL+++LF T    +   P+     +  V++ A
Sbjct: 237 PTQVHRKSVKKGFEFTLMVVGESGLGKSTLVNSLFLTDLYPERHIPSASEKIQQTVKIDA 58

Query: 83  RSYELQESNVRLKLTIVDT 101
            + E++E  V+L+LT+VDT
Sbjct: 57  STVEIEERGVKLRLTVVDT 1
>38061
          Length = 206

 Score = 52.8 bits (125), Expect = 3e-07,   Method: Composition-based stats.
 Identities = 23/30 (76%), Positives = 25/30 (83%)
 Frame = +3

Query: 228 MSVHLPFAVVGSTEEVKIGNKMAKARQYPW 257
           M+ HLPFAVVGS +EVKIGNKM KARQ  W
Sbjct: 117 MNSHLPFAVVGSNDEVKIGNKMVKARQGSW 206
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6754084|ref|NP_034488.1| glutathione S-transferase mu
1 [Mus musculus]
         (218 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

35754                                                                 167   4e-42
02955                                                                  60   6e-10
06833                                                                  48   3e-06
23210                                                                  28   2.0  
20544                                                                  28   3.7  
15529                                                                  28   4.1  
17671                                                                  27   7.5  
>35754
          Length = 581

 Score =  167 bits (422), Expect = 4e-42,   Method: Compositional matrix adjust.
 Identities = 83/181 (45%), Positives = 113/181 (62%), Gaps = 1/181 (0%)
 Frame = -2

Query: 36  GDAPDFDRSQWLNEKFKLGLDFPNLPYLIDGSHKITQSNAILRYLARKHHLDGETEEERI 95
           GDAPDF R  WL  K  LGLDFPNLPY IDG  K+TQSNAILRY+ARKH+L GET  E  
Sbjct: 553 GDAPDFSRDAWLKVKSSLGLDFPNLPYYIDGDIKLTQSNAILRYIARKHNLMGETPLESA 374

Query: 96  RADIVENQVMDTRMQLIMLCYNPDFEKQKPEFLKTIPEKMKLYSEFLGKRPWFAGDKVTY 155
           R +++    MD R  ++ + YNP +     E+   + E +  ++++L  + WFAGDKVT 
Sbjct: 373 RVEMMLENAMDFRNGVVRMVYNPKYTDLLEEYKPKVKETLAGFNKYLADKKWFAGDKVTV 194

Query: 156 VDFLAYDILDQYR-MFEPKCLDAFPNLRDFLARFEGLKKISAYMKSSRYIATPIFSKMAH 214
            DF  Y++LDQ+R M     L  +P L  F+A FE L  I  YM S +++  P+ +K+A 
Sbjct: 193 ADFHMYELLDQHRLMIGADVLKDYPKLTAFMAAFEALPAIKKYMASDKFMKRPVNNKVAA 14

Query: 215 W 215
           +
Sbjct: 13  F 11
>02955
          Length = 1322

 Score = 60.5 bits (145), Expect = 6e-10,   Method: Compositional matrix adjust.
 Identities = 51/201 (25%), Positives = 88/201 (43%), Gaps = 9/201 (4%)
 Frame = +1

Query: 7   YWNVRGLTHPIRMLLEYTDSSYDEKRYTMGD-APDFDRSQWLNEKFKLGLDFPNLPYLID 65
           Y+NVRG    +R+L       +++KR    D  PD D         K    +  +PY+I 
Sbjct: 37  YFNVRGKGEFLRLLFRAAGVQFEDKRIERADWGPDSDA--------KKATPYGQVPYVIY 192

Query: 66  GSHKITQSNAILRYLARKHHLDGETEEERIRADIVENQVMDTRM---QLIMLCYNPDFEK 122
              K  QS A+  Y ARK    G+T+E+  + + + + + D  +   +   L  +P  + 
Sbjct: 193 QGKKRGQSIAMGTYFARKFGFYGKTDEDAWKQEEIMHLIDDLIVGPNRAWFLEQDPQKKA 372

Query: 123 QKPEFLKTI--PEKMKLYSEFL---GKRPWFAGDKVTYVDFLAYDILDQYRMFEPKCLDA 177
           ++   L  +  P  +  +   L   G + +  GD VT  D   +D+L+     +P+ L +
Sbjct: 373 ERTRELTEVQYPRYLSSFERLLAENGDQGYSVGDSVTLADLCLHDVLETVLGVDPRALXS 552

Query: 178 FPNLRDFLARFEGLKKISAYM 198
           FP  R   A  E L  +  Y+
Sbjct: 553 FPLQRKLRANVENLPALKEYL 615
>06833
          Length = 882

 Score = 48.1 bits (113), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 54/210 (25%), Positives = 90/210 (42%), Gaps = 16/210 (7%)
 Frame = +3

Query: 5   LGYWNVRGLTHPIRMLLEYTDSSYDEKRYTMGDAPDFDRSQWLNEKFKLGLDFPNLPYL- 63
           L Y++ RG     R+LL      Y + R        FDR +W  + +K    F   P+L 
Sbjct: 105 LYYFDSRGFGEVSRLLLALAGQDYQDVR--------FDREEWA-QTYKAEAPFGQGPFLA 257

Query: 64  -----IDGSHKITQSNAILRYLARKHHLDGETEEERIRADIVENQVMDTRM--QLIMLCY 116
                     KI QS+AI  +LAR+  L G + ++    D V +   D  +  Q +ML  
Sbjct: 258 FTDSKTKKLKKIGQSSAIACFLAREFGLYGSSNQDGAVIDQVVHLYRDMVVAWQKVMLTE 437

Query: 117 NPD--FEKQKPEFLKTIPEKMKLYSEFL---GKRPWFAGDKVTYVDFLAYDILDQYRM-- 169
           + D   E  K    +  P+    +++ L      P+F G+ +T  D   YD + Q +   
Sbjct: 438 DADKKTEAHKKLMEEEFPKFFGHFNKLLEENSDSPFFVGNSITLADVYXYDXIFQVKKVT 617

Query: 170 -FEPKCLDAFPNLRDFLARFEGLKKISAYM 198
            ++P C +  P+L+    +   +  I AY+
Sbjct: 618 GYDP-CAN-HPSLQTLYDQVAEIPNIKAYV 701
>23210
          Length = 944

 Score = 28.5 bits (62), Expect = 2.0,   Method: Compositional matrix adjust.
 Identities = 24/72 (33%), Positives = 35/72 (48%), Gaps = 2/72 (2%)
 Frame = -1

Query: 56  DFPN--LPYLIDGSHKITQSNAILRYLARKHHLDGETEEERIRADIVENQVMDTRMQLIM 113
           D PN   P+L     +  QS AI  +LAR+++L G++  + IR D V     D    L  
Sbjct: 686 DAPNGQAPFLEYKGKRYGQSIAIANFLARENNLYGKSNLDAIRIDEVVQLTADVWAALGK 507

Query: 114 LCYNPDFEKQKP 125
             +  D EK +P
Sbjct: 506 AHFQTD-EK*RP 474
>20544
          Length = 1132

 Score = 27.7 bits (60), Expect = 3.7,   Method: Compositional matrix adjust.
 Identities = 12/45 (26%), Positives = 23/45 (51%)
 Frame = +2

Query: 124 KPEFLKTIPEKMKLYSEFLGKRPWFAGDKVTYVDFLAYDILDQYR 168
           +P + + + E + + S  L + P    D+  Y+D +  D  D+YR
Sbjct: 632 EPAYRQLVVEAVMVVSTILERNPELTFDQSVYLDKIMNDAFDEYR 766
>15529
          Length = 728

 Score = 27.7 bits (60), Expect = 4.1,   Method: Compositional matrix adjust.
 Identities = 11/29 (37%), Positives = 18/29 (62%)
 Frame = +3

Query: 69  KITQSNAILRYLARKHHLDGETEEERIRA 97
           + + + A    + ++HH DGE EEER R+
Sbjct: 510 RSSDNTAFTDKMVKRHHDDGEDEEERHRS 596
>17671
          Length = 591

 Score = 26.6 bits (57), Expect = 7.5,   Method: Compositional matrix adjust.
 Identities = 11/25 (44%), Positives = 17/25 (68%)
 Frame = -3

Query: 61  PYLIDGSHKITQSNAILRYLARKHH 85
           P +++ +HK TQ+N ILR + R  H
Sbjct: 232 PDIVNFTHKYTQNNNILRRIVRHFH 158
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31981338|ref|NP_036029.2| signal recognition particle
54a [Mus musculus]
         (504 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

24617                                                                 168   5e-42
03420                                                                 132   4e-31
17843                                                                  30   2.5  
03733                                                                  28   8.1  
>24617
          Length = 674

 Score =  168 bits (425), Expect = 5e-42,   Method: Compositional matrix adjust.
 Identities = 81/94 (86%), Positives = 88/94 (93%)
 Frame = -1

Query: 1   MVLADLGRKITSALRSLSNATIINEEVLNAMLKEVCTALLEADVNIKLVKQLRENVKSAI 60
           MVLADLGRKITSAL+SLSNATIINEEVLN MLKE+C ALLEADVNI+LVKQLRENV+S I
Sbjct: 287 MVLADLGRKITSALKSLSNATIINEEVLNGMLKEICAALLEADVNIRLVKQLRENVRSVI 108

Query: 61  DLEEMASGLNKRKMIQHAVFKELVKLVDPGVKAW 94
           D +EMA GLNKR+MIQ AVFKELVKL+DPGVKAW
Sbjct: 107 DFDEMAGGLNKRRMIQSAVFKELVKLIDPGVKAW 6
>03420
          Length = 2232

 Score =  132 bits (331), Expect = 4e-31,   Method: Compositional matrix adjust.
 Identities = 65/78 (83%), Positives = 69/78 (88%)
 Frame = +2

Query: 412 VSTRDVQELLTQYTKFAQMVKKMGGIKGLFKGGDMSKNVSQSQMAKLNQQMAKMMDPRVL 471
           VS R+V +LLTQY KFAQMVKKMGGIKGLFKGGDM KNV+ +QMAKLNQQMAKMMDPRVL
Sbjct: 2   VSVREVNDLLTQYKKFAQMVKKMGGIKGLFKGGDMGKNVNPTQMAKLNQQMAKMMDPRVL 181

Query: 472 HHMGGMAGLQSMMRQFQQ 489
             MGGM GLQ MMRQFQQ
Sbjct: 182 QQMGGMQGLQGMMRQFQQ 235
>17843
          Length = 772

 Score = 30.0 bits (66), Expect = 2.5,   Method: Compositional matrix adjust.
 Identities = 21/84 (25%), Positives = 37/84 (44%), Gaps = 2/84 (2%)
 Frame = +1

Query: 71  KRKMIQHAVFKELV--KLVDPGVKAWTPTKGKQNVIMFVGLQGSGKTTTCSKLAYYYQRK 128
           K +++ +A    L   K V+  + +W        VI+  G  G+GKTT C  LA+     
Sbjct: 106 KERLLNYATTTLLFSDKHVNSSIISW------NRVILLHGPPGTGKTTLCKALAH----- 252

Query: 129 GWKTCLICADTFRAGAFDQLKQNA 152
             K C+  +  F  G   ++  ++
Sbjct: 253 --KLCIRLSHRFSCGQLVEINSHS 318
>03733
          Length = 1281

 Score = 28.1 bits (61), Expect = 8.1,   Method: Compositional matrix adjust.
 Identities = 16/34 (47%), Positives = 20/34 (58%), Gaps = 2/34 (5%)
 Frame = +1

Query: 91  VKAWTP--TKGKQNVIMFVGLQGSGKTTTCSKLA 122
           V+  TP  TK +  ++M VGL GSGKT    K A
Sbjct: 877 VRGCTPPATKEECEILMMVGLPGSGKTVWSEKHA 978
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|9789881|ref|NP_062692.1| ADP-ribosylation factor-like
3 [Mus musculus]
         (182 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

18208                                                                 166   5e-42
09827                                                                 149   6e-37
08153                                                                 145   1e-35
33605                                                                 139   6e-34
10862                                                                 103   4e-23
11378                                                                  89   8e-19
32860                                                                  80   4e-16
15662                                                                  54   3e-08
06991                                                                  50   4e-07
18949                                                                  48   2e-06
19506                                                                  38   0.002
35581                                                                  35   0.013
33794                                                                  30   0.55 
11965                                                                  30   0.73 
29196                                                                  29   0.83 
38795                                                                  29   1.1  
>18208
          Length = 458

 Score =  166 bits (420), Expect = 5e-42,   Method: Compositional matrix adjust.
 Identities = 87/100 (87%), Positives = 97/100 (97%)
 Frame = -1

Query: 1   MGLLSILRKLKSAPDQEVRILLLGLDNAGKTTLLKQLASEDISHITPTQGFNIKSVQSQG 60
           MGLLS+LRKLKS+PD+E+RILLLGLDNAGKTTLLKQLASED SHITPTQGFNIKSVQS+G
Sbjct: 350 MGLLSLLRKLKSSPDRELRILLLGLDNAGKTTLLKQLASEDPSHITPTQGFNIKSVQSKG 171

Query: 61  FKLNVWDIGGQRKIRPYWRSYFENTDILIYVIDSADRKRF 100
           FKLNVWDIGGQR+IRPYW++YFENTD+LIYVIDS+D KR 
Sbjct: 170 FKLNVWDIGGQRRIRPYWKNYFENTDLLIYVIDSSDTKRM 51
>09827
          Length = 1201

 Score =  149 bits (376), Expect = 6e-37,   Method: Compositional matrix adjust.
 Identities = 71/166 (42%), Positives = 102/166 (61%)
 Frame = -3

Query: 16   QEVRILLLGLDNAGKTTLLKQLASEDISHITPTQGFNIKSVQSQGFKLNVWDIGGQRKIR 75
            +++RIL++GLD AGKTT+L +L   +I    PT GFN+++V+ +     VWD+GGQ KIR
Sbjct: 1118 KDMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNISFTVWDVGGQDKIR 939

Query: 76   PYWRSYFENTDILIYVIDSADRKRFXXXXXXXXXXXXXXXXSCVPVLIFANKQDLLTAAP 135
            P WR YF+NT  LI+V+DS D++R                     +L+FANKQDL  A  
Sbjct: 938  PLWRHYFQNTQGLIFVVDSNDKERVQEAREELTRMLNEDELRDAVLLVFANKQDLPHAMA 759

Query: 136  ASEIAEGLNLHTIRDRVWQIQSCSALTGEGVQDGMNWVCKNVNAKK 181
             +EI E L LH +R+R W IQS  A TG+G+ +G++W+   +   K
Sbjct: 758  TAEITEKLGLHGLRNRTWYIQSTCATTGDGLYEGLDWLSNQLKNNK 621
>08153
          Length = 1703

 Score =  145 bits (365), Expect = 1e-35,   Method: Compositional matrix adjust.
 Identities = 72/179 (40%), Positives = 105/179 (58%)
 Frame = +1

Query: 2   GLLSILRKLKSAPDQEVRILLLGLDNAGKTTLLKQLASEDISHITPTQGFNIKSVQSQGF 61
           G +S+ + L     +EVRIL++GLD AGKTT+L +L   +I    PT GFN+++V+ +  
Sbjct: 43  GFVSLFKNLFGK--KEVRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNI 216

Query: 62  KLNVWDIGGQRKIRPYWRSYFENTDILIYVIDSADRKRFXXXXXXXXXXXXXXXXSCVPV 121
              VWD+GGQ KIRP WR YF+NT  LI+V+DS DR+R                     +
Sbjct: 217 SFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERINEAKEELARMLNEDDLRDAII 396

Query: 122 LIFANKQDLLTAAPASEIAEGLNLHTIRDRVWQIQSCSALTGEGVQDGMNWVCKNVNAK 180
           L+FANKQDL  A  ASE+   L L  ++ R W +Q+  A +G+G+ +G+ W+   +  K
Sbjct: 397 LVFANKQDLPNAYSASEVTAHLGLANLKGRKWYMQATCATSGDGMYEGLEWLSTTLKHK 573
>33605
          Length = 888

 Score =  139 bits (351), Expect = 6e-34,   Method: Compositional matrix adjust.
 Identities = 63/99 (63%), Positives = 85/99 (85%)
 Frame = +1

Query: 1   MGLLSILRKLKSAPDQEVRILLLGLDNAGKTTLLKQLASEDISHITPTQGFNIKSVQSQG 60
           MGLL+IL+K+K   ++EVR+L+LGLDNAGKTT+LK+   EDI  I+PT GFNIK+++ +G
Sbjct: 451 MGLLTILKKMKQ-KEKEVRLLMLGLDNAGKTTILKKFNGEDIDTISPTLGFNIKTLEHRG 627

Query: 61  FKLNVWDIGGQRKIRPYWRSYFENTDILIYVIDSADRKR 99
           FKLNVWD+GGQ+ +R YWR+YFE+TD L++V+DSADR R
Sbjct: 628 FKLNVWDVGGQQSLRSYWRNYFESTDGLVWVVDSADRMR 744
>10862
          Length = 2896

 Score =  103 bits (257), Expect = 4e-23,   Method: Compositional matrix adjust.
 Identities = 52/123 (42%), Positives = 67/123 (54%)
 Frame = -3

Query: 54   KSVQSQGFKLNVWDIGGQRKIRPYWRSYFENTDILIYVIDSADRKRFXXXXXXXXXXXXX 113
            ++ Q Q  + NVWD+GGQ KIRP WR Y+  T  LI+V+D ADR R              
Sbjct: 2507 RNCQLQECQFNVWDVGGQDKIRPLWRHYYTGTQGLIFVVDCADRDRIDEARQELHRIIND 2328

Query: 114  XXXSCVPVLIFANKQDLLTAAPASEIAEGLNLHTIRDRVWQIQSCSALTGEGVQDGMNWV 173
                   +LIFANKQDL  A    EI E L L  +RDR W +Q   A TG+G+ +G+ W+
Sbjct: 2327 REMRDAIILIFANKQDLPDAMKPHEIQEKLGLTRLRDRNWYVQPSCATTGDGLCEGLTWL 2148

Query: 174  CKN 176
              N
Sbjct: 2147 TSN 2139

 Score = 44.7 bits (104), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 28/67 (41%), Positives = 39/67 (58%)
 Frame = -1

Query: 15   DQEVRILLLGLDNAGKTTLLKQLASEDISHITPTQGFNIKSVQSQGFKLNVWDIGGQRKI 74
            ++E+RIL+LGLD AGKTTLL ++         PT GFN+++V    FK NV  + G    
Sbjct: 2623 NKEMRILMLGLDAAGKTTLLYKMKLGQSVTXIPTVGFNVETVS---FK-NVNSMSGM*VG 2456

Query: 75   RPYWRSY 81
            R  +  Y
Sbjct: 2455 RTKYDRY 2435
>11378
          Length = 1688

 Score = 89.4 bits (220), Expect = 8e-19,   Method: Compositional matrix adjust.
 Identities = 47/172 (27%), Positives = 79/172 (45%), Gaps = 12/172 (6%)
 Frame = +3

Query: 19  RILLLGLDNAGKTTLLKQLASEDISHITPTQGFNIKSVQSQGFKLNVWDIGGQRKIRPYW 78
           +++ LGLDNAGKTTLL  L  + ++   PT     + +   G +   +D+GG R+ R  W
Sbjct: 327 KLVFLGLDNAGKTTLLHMLKDDKMAQHVPTLHPTSEELSMGGMRFTTFDLGGHRQARRVW 506

Query: 79  RSYFENTDILIYVIDSADRKRFXXXXXXXXXXXXXXXXSCVPVLIFANKQDLLTAAPASE 138
           + YF   D +++++D  DR+R                 +  P+L+  NK D   AA   E
Sbjct: 507 KDYFPAVDGIVFLVDVHDRERLVEAKAELDSLMTDEQVANAPILVLGNKIDKPGAASEEE 686

Query: 139 IAEGLNLHTIR------------DRVWQIQSCSALTGEGVQDGMNWVCKNVN 178
           I     L+++              R  ++  CS L  +G  +G  W+ + +N
Sbjct: 687 IRHWFGLNSLTTGKGTVARGELPGRPMELFMCSVLKRQGYGEGFRWMAQYIN 842
>32860
          Length = 330

 Score = 80.5 bits (197), Expect = 4e-16,   Method: Compositional matrix adjust.
 Identities = 36/89 (40%), Positives = 51/89 (57%)
 Frame = +2

Query: 78  WRSYFENTDILIYVIDSADRKRFXXXXXXXXXXXXXXXXSCVPVLIFANKQDLLTAAPAS 137
           W +Y+ N++ +I VIDS DR+R                     +L+FANKQD+     A+
Sbjct: 8   WNTYYSNSEFIIMVIDSTDRERLSITKEELCRMLATEELRXAALLVFANKQDIKGCMSAA 187

Query: 138 EIAEGLNLHTIRDRVWQIQSCSALTGEGV 166
           EI+  LNL +++D VW IQ+C  LTGEGV
Sbjct: 188 EISXQLNLTSVKDHVWHIQACCGLTGEGV 274
>15662
          Length = 455

 Score = 53.9 bits (128), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 29/116 (25%), Positives = 48/116 (41%), Gaps = 12/116 (10%)
 Frame = +2

Query: 75  RPYWRSYFENTDILIYVIDSADRKRFXXXXXXXXXXXXXXXXSCVPVLIFANKQDLLTAA 134
           R  W+ YF   D +++++D  DR+RF                +  P+L+  NK D   AA
Sbjct: 8   RRVWKDYFPAVDGIVFLVDVHDRERFVEAKAELDSLMTDEQVANAPILVLGNKIDKPGAA 187

Query: 135 PASEIAEGLNLHTIR------------DRVWQIQSCSALTGEGVQDGMNWVCKNVN 178
              EI     LH++              R  ++  CS L  +G  +G  W+ + +N
Sbjct: 188 SEDEIRHWFGLHSLTTGKGTVSRGELPGRPLELFMCSVLKRQGYGEGFRWMAQYIN 355
>06991
          Length = 1860

 Score = 50.4 bits (119), Expect = 4e-07,   Method: Compositional matrix adjust.
 Identities = 21/57 (36%), Positives = 37/57 (64%)
 Frame = -2

Query: 121  VLIFANKQDLLTAAPASEIAEGLNLHTIRDRVWQIQSCSALTGEGVQDGMNWVCKNV 177
            +++FANKQD+  A   +E+A  L L  +++R +QI   SA+ GEG+ + M W+  ++
Sbjct: 1829 LMVFANKQDIEGAMTVTEVANSLGLPGLKNRKYQIFKTSAVKGEGLDEAMEWLSNSL 1659
>18949
          Length = 414

 Score = 48.1 bits (113), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 19/70 (27%), Positives = 32/70 (45%)
 Frame = +3

Query: 60  GFKLNVWDIGGQRKIRPYWRSYFENTDILIYVIDSADRKRFXXXXXXXXXXXXXXXXSCV 119
           G     +D+GG R+ R  W+ YF   D +++++D  D +R                 + +
Sbjct: 54  GMTFTTFDLGGHRQARRVWKDYFPAVDGIVFIVDVHDTERITEAKAELDSLLRDDQIADI 233

Query: 120 PVLIFANKQD 129
           PVL+  NK D
Sbjct: 234 PVLVLGNKMD 263
>19506
          Length = 421

 Score = 38.1 bits (87), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 22/57 (38%), Positives = 32/57 (56%), Gaps = 5/57 (8%)
 Frame = -3

Query: 5   SILRKLKSA-----PDQEVRILLLGLDNAGKTTLLKQLASEDISHITPTQGFNIKSV 56
           S L K+ SA       + V ++  GLD AGKTTLL  L   ++    PT GFN++++
Sbjct: 188 STLLKMGSALCTLFRQKPVTVIYFGLDAAGKTTLLYNLKLGEVVTTIPTIGFNVETL 18
>35581
          Length = 364

 Score = 35.4 bits (80), Expect = 0.013,   Method: Compositional matrix adjust.
 Identities = 22/82 (26%), Positives = 41/82 (50%), Gaps = 6/82 (7%)
 Frame = +2

Query: 19  RILLLGLDNAGKTTLLKQLASED-----ISHITPTQGFNIKSVQSQGF-KLNVWDIGGQR 72
           + +LLG    GKT LL +LA++      ++ +T        ++ S     +++WD  GQ 
Sbjct: 50  KCVLLGDAGVGKTCLLNRLATDKFLDSPLTSLTTASLLTTVTLTSGVMASVDLWDTAGQE 229

Query: 73  KIRPYWRSYFENTDILIYVIDS 94
           + R    SY+ +T  ++ V D+
Sbjct: 230 RYRSLTSSYYRDTKAVLIVYDA 295
>33794
          Length = 779

 Score = 30.0 bits (66), Expect = 0.55,   Method: Compositional matrix adjust.
 Identities = 18/60 (30%), Positives = 27/60 (45%), Gaps = 2/60 (3%)
 Frame = -1

Query: 43  SHITPTQGFNIKSVQSQG--FKLNVWDIGGQRKIRPYWRSYFENTDILIYVIDSADRKRF 100
           SHI  T  +   ++  +G   KL +WD  GQ +     RSY      +I V D  ++  F
Sbjct: 710 SHILQTVAYKTTTILLEGKRVKLQIWDTSGQGRFCTIIRSYSRGAQGIILVYDITNKWSF 531
>11965
          Length = 3256

 Score = 29.6 bits (65), Expect = 0.73,   Method: Compositional matrix adjust.
 Identities = 14/38 (36%), Positives = 22/38 (57%)
 Frame = +1

Query: 55  SVQSQGFKLNVWDIGGQRKIRPYWRSYFENTDILIYVI 92
           S ++  FKL  +D+GGQR  R  W   FE+   +I+ +
Sbjct: 172 SFKNLNFKL--FDVGGQRSERKKWIHCFEDVTAIIFCV 279
>29196
          Length = 431

 Score = 29.3 bits (64), Expect = 0.83,   Method: Compositional matrix adjust.
 Identities = 14/40 (35%), Positives = 23/40 (57%)
 Frame = -2

Query: 53  IKSVQSQGFKLNVWDIGGQRKIRPYWRSYFENTDILIYVI 92
           I  +++  FKL  +D+GGQR  R  W   FE+   +I+ +
Sbjct: 241 ISPLKNLNFKL--FDVGGQRSERKKWIHCFEDVTAIIFCV 128
>38795
          Length = 792

 Score = 29.3 bits (64), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 15/37 (40%), Positives = 23/37 (62%)
 Frame = +1

Query: 6   ILRKLKSAPDQEVRILLLGLDNAGKTTLLKQLASEDI 42
           I + L    D + R+ L+G + AGK+TLLK ++ E I
Sbjct: 682 IYQNLDFGIDLDTRVALVGPNGAGKSTLLKLISGELI 792
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31981327|ref|NP_036100.2| proteasome (prosome,
macropain) subunit, beta type 2 [Mus musculus]
         (201 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

01337                                                                 166   6e-42
06516                                                                  47   4e-06
18720                                                                  33   0.11 
>01337
          Length = 2947

 Score =  166 bits (420), Expect = 6e-42,   Method: Compositional matrix adjust.
 Identities = 78/149 (52%), Positives = 101/149 (67%)
 Frame = -3

Query: 43   LLLCVGEAGDTVQFAEYIQKNVQLYKMRNGYELSPTAAANFTRRNLADCLRSRTPYHVNL 102
             L   GE GDTVQF+EYI KN+QLYKMRNGYELS  AAANFTRRN+AD LRS+ P  VN+
Sbjct: 1235 FLFTAGEPGDTVQFSEYISKNIQLYKMRNGYELSAKAAANFTRRNVADALRSQRPKFVNI 1056

Query: 103  LLAGYDEHEGPXXXXXXXXXXXXXXXXXXHGYGAFLTLSILDRYYTPTISRERAVELLRK 162
            L+AG D+  GP                  HGYG   TLSI+DRYY   ++++ AV LL++
Sbjct: 1055 LMAGMDD-SGPALFFLDYLGALIQVPFAVHGYGGMFTLSIMDRYYKKDMNKDEAVTLLQQ 879

Query: 163  CLEELQKRFILNLPTFSVRVIDKDGIPNL 191
            C+ E+QKRF++++P F  RV+ K G+ +L
Sbjct: 878  CVTEIQKRFLVDMPQFKARVVSKAGVEDL 792
>06516
          Length = 835

 Score = 47.4 bits (111), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 35/185 (18%), Positives = 77/185 (41%)
 Frame = +1

Query: 4   LIGIQGPDYVLVASDRVAASNIVQMKDDHDKMFKMSEKILLLCVGEAGDTVQFAEYIQKN 63
           ++ ++  D V++ +D    +         DK+ K++++I     G A DT   A+ ++ +
Sbjct: 130 IMAVEYEDGVVIGADSRTTTGAYIANRVTDKLTKVTDRIYCCRSGSAADTQAIADIVKYH 309

Query: 64  VQLYKMRNGYELSPTAAANFTRRNLADCLRSRTPYHVNLLLAGYDEHEGPXXXXXXXXXX 123
           +  Y+M  G E     AAN  R     C  +R      +++AG+D+  G           
Sbjct: 310 LDFYRMEMGEEPQVQTAANVFREL---CYDNRDSLTAGIIVAGWDKRTGGQVYSVPIGGM 480

Query: 124 XXXXXXXXHGYGAFLTLSILDRYYTPTISRERAVELLRKCLEELQKRFILNLPTFSVRVI 183
                    G G+      +D  + P++ ++  ++ + + +     R   +     + VI
Sbjct: 481 LQRQPFAIGGSGSTYLYGYVDAQFKPSMKKDDCLKFVSQAVSLAINRDGSSGGIIRMAVI 660

Query: 184 DKDGI 188
           +K+G+
Sbjct: 661 NKEGV 675
>18720
          Length = 433

 Score = 32.7 bits (73), Expect = 0.11,   Method: Compositional matrix adjust.
 Identities = 21/63 (33%), Positives = 34/63 (53%), Gaps = 2/63 (3%)
 Frame = +1

Query: 32 HDKM--FKMSEKILLLCVGEAGDTVQFAEYIQKNVQLYKMRNGYELSPTAAANFTRRNLA 89
          HD+M   ++SEK+ L+ V +        E  ++++++ K     E SPT AA+ T  N A
Sbjct: 19 HDRMVIHEVSEKLGLVHVSQG-------EGKERHLKVSKPSVKRESSPTPAASHTDSNSA 177

Query: 90 DCL 92
          DC 
Sbjct: 178DCT 186
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|51317397|ref|NP_598549.1| isoprenylcysteine carboxyl
methyltransferase [Mus musculus]
         (284 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

03721                                                                 120   6e-42
24127                                                                  31   0.50 
29177                                                                  29   1.9  
>03721
          Length = 1428

 Score =  120 bits (301), Expect(3) = 6e-42,   Method: Compositional matrix adjust.
 Identities = 52/80 (65%), Positives = 64/80 (80%)
 Frame = +2

Query: 202 SGVYAWCRHPSYVGWFYWSIGTQVMLCNPICGVVYALTVWRFFRDRTEEEEISLIHFFGE 261
            G   + RHP+YVGWFYWSIGTQVMLCNP+C + Y    WRFF +R  EEEI L++FFGE
Sbjct: 191 GGCLQFLRHPAYVGWFYWSIGTQVMLCNPLCLIGYTXVSWRFFSERVYEEEIYLLNFFGE 370

Query: 262 EYLDYKKRVPTGLPFIKGVK 281
           +YLDY++RVPTGLPFI+G +
Sbjct: 371 DYLDYQRRVPTGLPFIQGYR 430

 Score = 54.3 bits (129), Expect(3) = 6e-42,   Method: Compositional matrix adjust.
 Identities = 23/38 (60%), Positives = 28/38 (73%)
 Frame = +3

Query: 170 GECLRKAAMFTAGSNFNHVVQSEKSDTHTLVTSGVYAW 207
           GE LRK++MFTAG NFNH +Q  K   H LVT GVY++
Sbjct: 96  GEVLRKSSMFTAGRNFNHYIQHTKHQDHRLVTEGVYSF 209

 Score = 34.3 bits (77), Expect(3) = 6e-42,   Method: Compositional matrix adjust.
 Identities = 16/35 (45%), Positives = 23/35 (65%)
 Frame = +1

Query: 138 SSWIEFTLENIFWPELKQITWLSATGLLMVVFGEC 172
           +S  EFTLE  F+P +KQ+  L+  GL++ V G C
Sbjct: 1   ASLTEFTLEWFFFPGMKQLRLLNVLGLMLTVGGRC 105
>24127
          Length = 1368

 Score = 31.2 bits (69), Expect = 0.50,   Method: Compositional matrix adjust.
 Identities = 21/44 (47%), Positives = 30/44 (68%)
 Frame = -3

Query: 103 FHYSEYLVTAVNNPKSLSLDSFLLNHSLEYTVAALSSWIEFTLE 146
           FH+S++  T +NN KSLS+ SF L+H L Y   AL+S+   T+E
Sbjct: 583 FHHSDHSTTIINNBKSLSV-SFFLSHYLFY-Y*ALASYSVLTVE 458
>29177
          Length = 1146

 Score = 29.3 bits (64), Expect = 1.9,   Method: Compositional matrix adjust.
 Identities = 21/62 (33%), Positives = 31/62 (50%)
 Frame = -1

Query: 192 EKSDTHTLVTSGVYAWCRHPSYVGWFYWSIGTQVMLCNPICGVVYALTVWRFFRDRTEEE 251
           E   +H L  + V+  C H ++VG F+  +   V+LC  +CGV Y L    F R    E 
Sbjct: 405 ETGGSHXL--NKVFLNCFHSNHVGLFHVWLQLHVLLC--VCGVCYVL----FVRVGGGER 250

Query: 252 EI 253
           E+
Sbjct: 249 EV 244
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|84579909|ref|NP_001033752.1| mitogen activated
protein kinase 1 [Mus musculus]
         (358 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

14126                                                                 167   6e-42
01060                                                                 164   7e-41
29581                                                                 151   4e-37
01756                                                                 147   4e-36
01707                                                                 142   3e-34
04591                                                                 128   4e-30
04138                                                                 110   6e-25
32000                                                                 110   7e-25
31489                                                                 100   9e-22
18287                                                                  91   7e-19
13592                                                                  89   2e-18
01966                                                                  86   1e-17
03508                                                                  83   2e-16
23319                                                                  82   3e-16
15910                                                                  80   2e-15
00300                                                                  79   2e-15
18921                                                                  79   3e-15
12721                                                                  79   3e-15
09606                                                                  76   2e-14
01392                                                                  75   4e-14
06405                                                                  72   5e-13
28638                                                                  60   7e-13
18484                                                                  71   7e-13
03294                                                                  70   1e-12
26560                                                                  69   2e-12
14420                                                                  68   5e-12
12453                                                                  67   1e-11
13212                                                                  66   2e-11
21808                                                                  66   2e-11
19761                                                                  66   2e-11
13066                                                                  65   3e-11
11185                                                                  65   4e-11
30755                                                                  65   4e-11
19094                                                                  65   4e-11
31885                                                                  64   7e-11
04852                                                                  64   7e-11
27546                                                                  64   1e-10
18401                                                                  63   2e-10
01718                                                                  62   5e-10
07940                                                                  62   5e-10
00715                                                                  60   2e-09
21079                                                                  59   3e-09
12786                                                                  58   6e-09
27405                                                                  57   9e-09
03240                                                                  57   9e-09
18996                                                                  57   1e-08
00392                                                                  56   2e-08
17300                                                                  56   2e-08
11780                                                                  55   4e-08
14116                                                                  55   6e-08
26711                                                                  54   7e-08
05084                                                                  54   7e-08
21433                                                                  54   8e-08
26909                                                                  53   2e-07
19301                                                                  52   3e-07
28157                                                                  49   2e-06
01106                                                                  49   3e-06
14477                                                                  48   6e-06
13078                                                                  47   1e-05
07291                                                                  46   2e-05
00638                                                                  45   4e-05
20640                                                                  45   5e-05
07836                                                                  44   7e-05
37602                                                                  44   1e-04
11404                                                                  43   2e-04
02638                                                                  43   2e-04
16708                                                                  42   3e-04
37063                                                                  42   3e-04
22005                                                                  42   4e-04
16003                                                                  41   8e-04
29360                                                                  40   0.001
32359                                                                  40   0.002
20559                                                                  39   0.002
17975                                                                  39   0.003
12672                                                                  38   0.005
21800                                                                  38   0.008
18481                                                                  37   0.009
17253                                                                  37   0.012
20152                                                                  36   0.025
18663                                                                  35   0.048
15931                                                                  33   0.12 
26009                                                                  33   0.14 
16350                                                                  32   0.28 
20513                                                                  32   0.28 
36481                                                                  32   0.29 
24241                                                                  31   0.71 
35032                                                                  31   0.86 
17011                                                                  29   2.4  
02980                                                                  28   5.7  
07988                                                                  28   6.7  
>14126
          Length = 1265

 Score =  167 bits (423), Expect = 6e-42,   Method: Compositional matrix adjust.
 Identities = 104/303 (34%), Positives = 161/303 (53%), Gaps = 8/303 (2%)
 Frame = +3

Query: 22  RYTNLSYIGEGAYGMVCSAYDNLNKVR-VAIKKIS-PFEHQTYCQRTLREI---KILLRF 76
           +Y  ++ IG GAYG V  A D  N+   VA+K+I      +      +REI   K L ++
Sbjct: 192 KYEEVAVIGNGAYGTVYKARDLRNQGEFVAMKRIRLNNTEEGMPMMAIREISMLKQLEQY 371

Query: 77  RHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLK---TQHLSNDHICYFLYQILR 133
            H N++ + D+      ++   + +V + +E DL   L    +  L  D I   + Q+L 
Sbjct: 372 EHPNVVRLLDVSHNTITDREIRLNLVFEYIEHDLATYLAKCPSPGLGPDRIKDLMLQLLN 551

Query: 134 GLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTGFLTEYVATRWYRA 193
           G+ ++HS  ++HRDLKP NLL++    LK+ DFGLAR+    +     LT  V T WYR+
Sbjct: 552 GVDFLHSNRIVHRDLKPQNLLISKDGRLKLADFGLARI----YSFHMALTTVVVTLWYRS 719

Query: 194 PEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCI 253
           PE+++ ++ Y  S+DIWS GCI AE+ + R +F G    DQL  I  ++G P   D    
Sbjct: 720 PEVLMQAE-YGTSVDIWSCGCIFAELFTRRALFKGSSEFDQLKKIFEVIGLPPAGDWPEG 896

Query: 254 INLKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPYLEQ 313
           +++   ++  + P    VP   L P  D +A DL++KML F   +RI   ++L HPYL  
Sbjct: 897 VSVHRNSFRPTPP----VPLQTLVPEMDPQAKDLMEKMLVFKSGRRISSRESLLHPYLRD 1064

Query: 314 YYD 316
             D
Sbjct: 1065DLD 1073
>01060
          Length = 1800

 Score =  164 bits (414), Expect = 7e-41,   Method: Compositional matrix adjust.
 Identities = 104/312 (33%), Positives = 163/312 (52%), Gaps = 11/312 (3%)
 Frame = +1

Query: 24  TNLSYIGEGAYGMVCSAYDNLNKVRVAIKKISPFEHQTYC-QRTLREIKILLRFRHENII 82
           T+   IGEG YG+V          ++A+KKI     +       +REI +L   RH NI+
Sbjct: 82  TDFQKIGEGTYGVVYKCRHRATGRKLAMKKIRLRGSEDGVPSSAIREIAMLRELRHTNIV 261

Query: 83  GINDIIRAPTIEQMKD--VYIVQDLMETDLY----KLLKTQHLSNDHICYFLYQILRGLK 136
            + D+I       M+D  +++V + +  DL     K  +   L    +  +++QI+ G+ 
Sbjct: 262 CLEDVI-------MEDERLFLVFEFLSMDLKMYIDKFPEGVVLDRRLVKSYVFQIVTGIX 420

Query: 137 YIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARV-ADPDHDHTGFLTEYVATRWYRAPE 195
           + H   ++HRDLKP NLL+N T  +KI DFG+AR  A P   +T      V T WYRAPE
Sbjct: 421 FCHQRRIVHRDLKPQNLLINHTGAIKIADFGMARTFALPVRAYT----HEVVTLWYRAPE 588

Query: 196 IMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIIN 255
           I++ +  Y+  +D+WS+G I A+ML   PIF G   +DQL  I  I+G+P+++       
Sbjct: 589 ILMGASKYSTPVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIFRIIGTPTEQTWPEFHK 768

Query: 256 LKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPY---LE 312
           L A N +  L  + K+  +    + DS  LDL+++ L  +P +RI  ++ L H Y   ++
Sbjct: 769 LPAFNGMFPLWKEGKL--SETLTDLDSLGLDLIERTLKCDPAQRISCKKMLQHAYFLNVD 942

Query: 313 QYYDPSDEPIAE 324
               P D P  E
Sbjct: 943 TSVKPVDVPSPE 978
>29581
          Length = 1278

 Score =  151 bits (381), Expect = 4e-37,   Method: Compositional matrix adjust.
 Identities = 88/255 (34%), Positives = 137/255 (53%), Gaps = 7/255 (2%)
 Frame = -2

Query: 72   ILLRFRHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQH--LSNDHICYFLY 129
             LL  RH+NI+ + +++   +++ +   ++V +  E DL  LL       S   +   + 
Sbjct: 1196 FLLNLRHQNIVQLQEVVVGKSLDSL---FLVMEYCEQDLASLLDNMPAPFSESQVKCIVL 1026

Query: 130  QILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLAR-VADPDHDHTGFLTEYVAT 188
            Q+L+GL+Y+H A ++HRDLK SNLL+     +KI DFGLAR    P       +T  V T
Sbjct: 1025 QLLKGLRYLHEAFIIHRDLKVSNLLMTDKGCVKIADFGLARNYGKPQKP----MTPKVVT 858

Query: 189  RWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQE 248
             WYRAPE++  SK ++ +ID+WS GCIL E+L ++P+ PG+  L Q+  I+ +LG+P+  
Sbjct: 857  LWYRAPELLFGSKTHSTAIDMWSAGCILGELLGHKPLMPGRSDLQQIELIMELLGTPNDT 678

Query: 249  DLNCIINLKA-RNYLLSLPHKNKVPWNRL---FPNADSKALDLLDKMLTFNPHKRIEVEQ 304
                   L A   + L      K P+N L   FP      + LL+ +  ++P KR   E 
Sbjct: 677  IWPGFSQLPAFEQFTL-----KKQPYNNLRHTFPWLSESGIRLLNGLFMYHPQKRATAED 513

Query: 305  ALAHPYLEQYYDPSD 319
             L H Y ++   P D
Sbjct: 512  CLEHSYFKEQPYPCD 468
>01756
          Length = 1858

 Score =  147 bits (372), Expect = 4e-36,   Method: Compositional matrix adjust.
 Identities = 110/313 (35%), Positives = 164/313 (52%), Gaps = 7/313 (2%)
 Frame = -3

Query: 18   DVGPRYTNLSYIGEGAYGMVCSAYDNLNKVRVAIKKI-SPFEHQTYCQRTLREIKILLRF 76
            D   +Y  L+ IG+G +G V  A     K  VA+KK+    E + +    LREIKIL   
Sbjct: 1751 DEDAKYEKLAKIGQGTFGEVFKARCKKTKQVVAMKKVLMDNEKEGFPITALREIKILQLL 1572

Query: 77   RHENIIGINDI--IRAPTIEQMKDV-YIVQDLMETDLYKLLKTQHLSND--HICYFLYQI 131
             HEN++ + +I   +A +  + K + Y+V +  E DL  LL    +  +   I   + Q+
Sbjct: 1571 NHENVVDLIEICSTKATSANRYKSMFYLVFEFCEHDLAGLLSNMSVVFNLPEIKEVMKQL 1392

Query: 132  LRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTGFLTEYVATRWY 191
            + GL YIH   +LHRD+K +N+L+     LK+ DFGLAR    +       T  V T WY
Sbjct: 1391 MNGLYYIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRVVTLWY 1212

Query: 192  RAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLN 251
            R PE++L  + Y+ +ID W  GCI+AEM +  PI  G    +QL  I  + GS + E   
Sbjct: 1211 RPPELLLGDRNYSTAIDQWGAGCIMAEMWTRNPIMQGTTEQNQLTLITQLCGSITPEVWP 1032

Query: 252  CIINLKARNYL-LSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPY 310
             +  L+  N L L   +K KV     +   D+ ALDLLDK+L  +P KR+  ++AL+H +
Sbjct: 1031 GVERLELYNSLDLPQGNKRKVKERLRYYIKDAYALDLLDKLLALDPGKRVNSDEALSHDF 852

Query: 311  LEQYYDPSDEPIA 323
               + DP   P+ 
Sbjct: 851  F--WMDPEPLPLT 819
>01707
          Length = 757

 Score =  142 bits (357), Expect = 3e-34,   Method: Compositional matrix adjust.
 Identities = 75/226 (33%), Positives = 127/226 (56%), Gaps = 3/226 (1%)
 Frame = +1

Query: 22  RYTNLSYIGEGAYGMVCSAYDNLNKVRVAIKKISPFEHQTYCQR-TLREIKILLRFRHEN 80
           +Y  +  IGEG+YG+V    +      VAIKK    E     ++  +REI++L + +H N
Sbjct: 67  KYEKIGKIGEGSYGVVFKCRNKETSQLVAIKKFVESEDDPLIKKIAMREIRMLKQLKHPN 246

Query: 81  IIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKT--QHLSNDHICYFLYQILRGLKYI 138
           ++ + ++ R     + K +++V D ++  L   L    + L    +   +YQ L  + + 
Sbjct: 247 LVRLIEVFR-----RKKRLHLVFDYVDHTLLNELDRYPRGLPEPMVKRIIYQTLLAVNFC 411

Query: 139 HSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTGFLTEYVATRWYRAPEIML 198
           H  N +HRD+KP N+L+     +K+CDFG AR+     D     T+YVATRWYRAPE+++
Sbjct: 412 HQYNTIHRDVKPENILITRQGQVKLCDFGFARILTGPGDE---YTDYVATRWYRAPELLV 582

Query: 199 NSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGS 244
               Y   +D+W++GC+ AE+L+ + ++PG+  +DQL+ I   LG 
Sbjct: 583 GDTQYGPPVDVWAIGCVFAELLTGQALWPGRSDVDQLHLIRKTLGD 720
>04591
          Length = 1117

 Score =  128 bits (321), Expect = 4e-30,   Method: Compositional matrix adjust.
 Identities = 88/263 (33%), Positives = 132/263 (50%), Gaps = 7/263 (2%)
 Frame = -2

Query: 66   TLREIKILLRFRHENIIGINDIIR---APTIEQMKDVYIVQDLMETDLYKLLKTQHL--S 120
             LREIKIL +  HEN++ + +I      P        Y++ +  + DL  LL    +  S
Sbjct: 1080 ALREIKILQQLEHENVVQLQEICHTQAGPYNRYKSTFYLIFEYCDYDLAGLLNNLRVKFS 901

Query: 121  NDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTG 180
                   + Q+L GL YIH+  +LHRD+K +N+LL     LK+ DFGL+R        + 
Sbjct: 900  LADKKNLMSQLLNGLFYIHTKQILHRDIKAANILLTRDGVLKLADFGLSR----PWVKSK 733

Query: 181  FLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILG 240
             LT  V T WYR PE++L  + Y   ID+W VGCI+AEM S +P+  G+    QL+ I  
Sbjct: 732  RLTNRVVTLWYRPPELLLGEREYGPEIDMWGVGCIMAEMWSRKPLMQGRSEQHQLSLITD 553

Query: 241  ILGSPSQEDLNCIINLKARNYLLSLPHKN--KVPWNRLFPNADSKALDLLDKMLTFNPHK 298
            + GS + E    +  L+     L LP     KV    L    + +  +L+D  L  +P +
Sbjct: 552  LCGSLNAEVWPGVTKLELYGK-LDLPQGKPRKVKERMLDLLKNKEGAELIDIFLRLDPGQ 376

Query: 299  RIEVEQALAHPYLEQYYDPSDEP 321
            R+  + AL+H +   + DP   P
Sbjct: 375  RMNCDNALSHDFF--WVDPLPSP 313
>04138
          Length = 800

 Score =  110 bits (276), Expect = 6e-25,   Method: Compositional matrix adjust.
 Identities = 63/186 (33%), Positives = 94/186 (50%), Gaps = 3/186 (1%)
 Frame = +1

Query: 135 LKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTGFLTEYVATRWYRAP 194
           L YIH   +LHRD+K +N+L+     LK+ DFGLAR    +       T  V T WYR P
Sbjct: 52  LYYIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRVVTLWYRPP 231

Query: 195 EIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCII 254
           E++L  + Y+ +ID W  GCI+AEM +  PI  G    +QL  I  + GS + E    + 
Sbjct: 232 ELLLGDRNYSTAIDQWGAGCIMAEMWTRNPIMQGTTEQNQLTLITQLCGSITPEVWPGVT 411

Query: 255 NLKARNYL---LSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPYL 311
            L   + +   L+   KN +         D   LDL +++L  +P +RI  ++AL H + 
Sbjct: 412 QLSMYHQIKGALAAGRKNIIRDRFARILKDPYGLDLFERLLKMDPSQRISADEALNHDFF 591

Query: 312 EQYYDP 317
               +P
Sbjct: 592 WVGVEP 609
>32000
          Length = 644

 Score =  110 bits (276), Expect = 7e-25,   Method: Compositional matrix adjust.
 Identities = 64/157 (40%), Positives = 87/157 (55%), Gaps = 3/157 (1%)
 Frame = -1

Query: 158 TCDLKICDFGLARVAD-PDHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCIL 216
           T  +KI DFGLARV   P   +T      V T WYRAPEI+L  + Y+  +DIWS+GCI 
Sbjct: 581 TAKMKIADFGLARVFGLPVRTYT----HEVITLWYRAPEILLGCRFYSVPVDIWSLGCIF 414

Query: 217 AEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRL 276
            EM++ R +FPG   +DQL  I   LG+P ++    +  L   +Y  + P   K P   L
Sbjct: 413 VEMMTRRALFPGDSEIDQLYRIFRTLGTPDEKVWPGVSKLP--DYKPTFP---KWPLKNL 249

Query: 277 --FPNADSKALDLLDKMLTFNPHKRIEVEQALAHPYL 311
               +     LDLL +MLT+NP++RI    A+ HPY 
Sbjct: 248 ETVVSLSKVGLDLLKRMLTYNPNRRISARSAMRHPYF 138
>31489
          Length = 329

 Score =  100 bits (249), Expect = 9e-22,   Method: Compositional matrix adjust.
 Identities = 52/87 (59%), Positives = 70/87 (80%), Gaps = 2/87 (2%)
 Frame = +3

Query: 70  IKILLRFRHENIIGINDIIR-APTIEQMKDVYIVQDLMETDLYKLLKT-QHLSNDHICYF 127
           IKIL  F+H+NII I +I++   +    KD+++V DLME+DL++++ + Q L+ +HI YF
Sbjct: 3   IKILKHFKHDNIISIREILKPKDSYHDFKDIHVVFDLMESDLHRIIYSDQPLTEEHIRYF 182

Query: 128 LYQILRGLKYIHSANVLHRDLKPSNLL 154
           LYQILRGLKYIHSANV+HRDLKPSNLL
Sbjct: 183 LYQILRGLKYIHSANVVHRDLKPSNLL 263
>18287
          Length = 678

 Score = 90.9 bits (224), Expect = 7e-19,   Method: Compositional matrix adjust.
 Identities = 49/113 (43%), Positives = 72/113 (63%), Gaps = 2/113 (1%)
 Frame = -3

Query: 203 YTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINLKARNYL 262
           Y  SIDIWSVGCI AE+LS R +F  +  + QL+ I+ ++G+P  ED+       ARN++
Sbjct: 673 YDYSIDIWSVGCIFAELLSRRILFQAQGPVQQLDMIINLVGTPRPEDMERACE-GARNHI 497

Query: 263 LSLP--HKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPYLEQ 313
           L+ P   +N +    L P+A  +A+ LL +ML  NP  RI  E+AL+HPYL++
Sbjct: 496 LNQPFRRQNLLTLYNLSPHATHEAVRLLTRMLILNPKNRISAEEALSHPYLDE 338
>13592
          Length = 980

 Score = 89.4 bits (220), Expect = 2e-18,   Method: Compositional matrix adjust.
 Identities = 66/202 (32%), Positives = 107/202 (52%), Gaps = 7/202 (3%)
 Frame = +2

Query: 29  IGEGAYGMVCSAYDNLNKVRVAIKKISPFEHQTYCQRTL-REIKILLRFRHENIIGINDI 87
           IG+G +G V +A +N     +A+K+I+    +T   + +  E+KIL   +H+N++     
Sbjct: 8   IGQGRFGKVYTAVNNNTGELMAMKEIAIQPGETRALKNVAEELKILEGIKHKNLV----- 172

Query: 88  IRAPTIE-QMKDVYIVQDLM-ETDLYKLLK-TQHLSNDHICYFLYQILRGLKYIHSANVL 144
            R   IE   +++ I  +L  E  L  L++ T  L       F  Q+L G+  +H   ++
Sbjct: 173 -RYYGIEVHREELLIFMELCSEGTLESLVELTGGLPEALSRRFTAQLLSGVAELHKHGIV 349

Query: 145 HRDLKPSNL-LLNTTCDLKICDFGLARVADPDHDHTGFLTEYVATRWYRAPEIML--NSK 201
           HRD+K +N+ L++ +  LK+ DFG A          G L  YV T+ Y APE+    NS 
Sbjct: 350 HRDIKTANIFLVDGSNSLKLGDFGSAVKIQAHTTVPGELQGYVGTQAYMAPEVFTKTNSD 529

Query: 202 GYTKSIDIWSVGCILAEMLSNR 223
           G+ +  DIWSVGC++ EM S +
Sbjct: 530 GHGRLADIWSVGCVVVEMASGK 595
>01966
          Length = 1735

 Score = 85.5 bits (210), Expect(2) = 1e-17,   Method: Compositional matrix adjust.
 Identities = 54/157 (34%), Positives = 84/157 (53%), Gaps = 7/157 (4%)
 Frame = -1

Query: 66   TLREIKILLRFRHENIIGINDIIRAPTIEQMKD--VYIVQDLMETDLY----KLLKTQHL 119
             +REI +L   RH NI+ + D+I       M+D  +++V + +  DL     K  +   L
Sbjct: 1573 AIREIAMLRELRHTNIVCLEDVI-------MEDERLFLVFEFLSMDLKMYIDKFPEGVVL 1415

Query: 120  SNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARV-ADPDHDH 178
                +  +++QI+ G+ + H   ++HRDLKP NLL+N T  +KI DFG+AR  A P   +
Sbjct: 1414 DRRLVKSYVFQIVTGINFCHQRRIVHRDLKPQNLLINHTGAIKIADFGMARTFALPVRAY 1235

Query: 179  TGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCI 215
                T  V T WYRAPEI++   G   +   W+ G +
Sbjct: 1234 ----THEVVTLWYRAPEILM---GPQSTPPXWTCGAL 1145

 Score = 21.2 bits (43), Expect(2) = 1e-17,   Method: Compositional matrix adjust.
 Identities = 9/12 (75%), Positives = 10/12 (83%)
 Frame = -2

Query: 26   LSYIGEGAYGMV 37
            LS IGEG YG+V
Sbjct: 1695 LSKIGEGTYGVV 1660

 Score = 73.2 bits (178), Expect = 2e-13,   Method: Compositional matrix adjust.
 Identities = 41/129 (31%), Positives = 67/129 (51%), Gaps = 3/129 (2%)
 Frame = -3

Query: 199  NSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINLKA 258
             +  Y+  +D+WS+G I A+ML   PIF G   +DQL  I  I+G+P+++       L A
Sbjct: 1187 GASKYSTPVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIFRIIGTPTEQTWPEFHKLPA 1008

Query: 259  RNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPY---LEQYY 315
             N +  L  + K+  +    + DS  LDL+++ L  +P +RI  ++ L H Y   ++   
Sbjct: 1007 FNGMFPLWKEGKL--SETLTDLDSLGLDLIERTLKCDPAQRISCKKMLQHAYFLNVDTSV 834

Query: 316  DPSDEPIAE 324
             P D P  E
Sbjct: 833  KPVDVPSPE 807
>03508
          Length = 1463

 Score = 83.2 bits (204), Expect = 2e-16,   Method: Compositional matrix adjust.
 Identities = 44/150 (29%), Positives = 88/150 (58%), Gaps = 2/150 (1%)
 Frame = +1

Query: 80  NIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQHLSNDHICYFLYQILRGLKYIH 139
           N+I +  I++ P         I + +  TD  +L +T   ++  I ++LY++++ L + H
Sbjct: 757 NVITLLAIVKDPV--SRTPALIFEHVNNTDFKQLYQT--FTDYDIRFYLYELMKALDFCH 924

Query: 140 SANVLHRDLKPSNLLLN-TTCDLKICDFGLARVADPDHDHTGFLTEYVATRWYRAPEIML 198
           S  ++HRD+KP N++++     L++ D+GLA    P  ++       VA+R+++ PE++L
Sbjct: 925 SMGIMHRDVKPHNVMIDHENKKLRLIDWGLAEFYHPGMEYN----VRVASRYFKGPELLL 1092

Query: 199 NSKGYTKSIDIWSVGCILAEMLSNR-PIFP 227
           + + Y  S+D+WS+GC+ A M+  + P+ P
Sbjct: 1093DYQMYDYSLDMWSLGCMFASMIFRKEPLLP 1182

 Score = 40.4 bits (93), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 39/137 (28%), Positives = 59/137 (43%), Gaps = 15/137 (10%)
 Frame = +2

Query: 190  WYRAPEIMLNSKGYTKSIDI-WSVG----CILAEMLSNRPIFPGKHYLDQLNHILGILGS 244
            W RA     N    T+ +   W+ G    C+ A      P F G    DQL  I  +LG+
Sbjct: 1055 WRRATSRDQNYCWTTRCMTTHWTCGVWAACLPA*SSGKSPFFHGHDNYDQLVRIAKVLGT 1234

Query: 245  PSQEDL-----NCIINLKARNYLLSLPHKNKVPWNRLFPNADS-----KALDLLDKMLTF 294
               +DL        I+L  R   +   H  K  W R   + +      +ALD LDK+L +
Sbjct: 1235 ---DDLYGYIEKYQIDLDPRFNDILGRHSRKR-WERFVHSENQHLISPEALDFLDKLLRY 1402

Query: 295  NPHKRIEVEQALAHPYL 311
            + ++R+   +A+ HPY 
Sbjct: 1403 DHNERLTAREAMDHPYF 1453
>23319
          Length = 2235

 Score = 82.4 bits (202), Expect = 3e-16,   Method: Compositional matrix adjust.
 Identities = 42/113 (37%), Positives = 63/113 (55%), Gaps = 1/113 (0%)
 Frame = +3

Query: 200 SKGYTKSIDIWSVGCILAEML-SNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINLKA 258
           +K Y+ SID+WS GCI AE+  + RP+FPG    DQL  I  +LG+P+++    +  L  
Sbjct: 18  AKMYSTSIDMWSAGCIFAELANAGRPLFPGNDDDDQLKRIFKLLGTPTEDQWPGMTQLP- 194

Query: 259 RNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPYL 311
            NY +   +     W ++ P  +SK  DLL  +L   P  R+  ++AL HPY 
Sbjct: 195 -NYRMFPMYHVTTTWQQVVPKLNSKGRDLLQCLLVCCPSDRMSADEALQHPYF 350
>15910
          Length = 1361

 Score = 79.7 bits (195), Expect = 2e-15,   Method: Compositional matrix adjust.
 Identities = 56/185 (30%), Positives = 88/185 (47%), Gaps = 3/185 (1%)
 Frame = +2

Query: 131 ILRGLKYIHSANVLHRDLKPSNLLLNTTCD---LKICDFGLARVADPDHDHTGFLTEYVA 187
           IL G++YIH+  V+HRDLKP NLL     D   LK+ DFGL+R+ +P+      ++    
Sbjct: 491 ILHGVQYIHANGVVHRDLKPENLLYECMTDDSKLKLADFGLSRIIEPEVQ----MSTVCG 658

Query: 188 TRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQ 247
           T  Y APE++   K YT S+D+WSVG I   +L     F  ++  +    I+       +
Sbjct: 659 TPGYCAPEVLKGDK-YTPSVDMWSVGVIAYILLCGYEPFFAENEFEMYRKIIKGEYKFDE 835

Query: 248 EDLNCIINLKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQALA 307
           E                        W+ +  NA     D++ K+L  +P KR+   +AL 
Sbjct: 836 E-----------------------YWSEISENAK----DVVRKLLVIDPKKRLTATEALR 934

Query: 308 HPYLE 312
            P+++
Sbjct: 935 LPWVK 949
>00300
          Length = 2318

 Score = 79.3 bits (194), Expect = 2e-15,   Method: Compositional matrix adjust.
 Identities = 77/310 (24%), Positives = 134/310 (43%), Gaps = 8/310 (2%)
 Frame = -1

Query: 13   RGQVFDVGPRYTNLSYIGEGAYGMVCSAYDNLNKVRVAIK--KISPFEHQTYCQRTLREI 70
            R  V  V  R+   + IGEG +G V +A +      +A+K  K  P + Q   +    EI
Sbjct: 1682 RINVRRVNFRWQRGNKIGEGQFGKVYTAVNMSTGELMALKEMKFQPNDLQQ-LREMCDEI 1506

Query: 71   KILLRFRHENIIGINDIIRAPTIEQMKD-VYIVQDLMETDLYKLLKTQHLSNDHICYFLY 129
            KI    +HEN++      +   +E  KD + +  +  +T   +      L    I  +  
Sbjct: 1505 KIFEGIQHENLV------KYYGVEVHKDEMLMFMEYCDTGTIEEAAKMGLPEYLIRRYTR 1344

Query: 130  QILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTGFLTEYVATR 189
            +I+  + ++H  +++HRD+K +N+ L +   +K+ DFG +          G     V T 
Sbjct: 1343 EIVLAVNHLHENSIVHRDIKGANIFLTSNGHVKLGDFGCSVKLKSHTTMPGEFHNLVGTT 1164

Query: 190  WYRAPEIML--NSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQ 247
             Y APE+    +  GY ++ DIWS+GC++ EM + +  +   H LD    I+        
Sbjct: 1163 AYMAPEVFTQNDQGGYGRAADIWSLGCVVIEMATGKRPW---HDLDNNYQIM-------- 1017

Query: 248  EDLNCIINLKARNYLLSLPHKNKVPWNRLFPNADSKALD---LLDKMLTFNPHKRIEVEQ 304
                         Y + + HK  VP        DS +++    LD ++  +P +R    Q
Sbjct: 1016 -------------YKVGIGHKPAVP--------DSLSVEGKHFLDLIMCHDPAQRALASQ 900

Query: 305  ALAHPYLEQY 314
             L H + + Y
Sbjct: 899  LLDHTFTKVY 870
>18921
          Length = 697

 Score = 79.0 bits (193), Expect = 3e-15,   Method: Compositional matrix adjust.
 Identities = 64/213 (30%), Positives = 98/213 (46%), Gaps = 4/213 (1%)
 Frame = +2

Query: 16  VFDVGPRYTNLSYIGEGAYGMVCSAYDNLNKVRVAIKKISPFEHQTYCQRTLREIKILLR 75
           VFD+      L  +GEG+YG   S + +L+K    +  I      T  Q  ++EI I+ +
Sbjct: 32  VFDI------LGKLGEGSYG---SVFKSLHKETGQVLAIKQVPVDTDLQEIIKEISIMQQ 184

Query: 76  FRHENIIGINDIIRAPTIEQMKDVYIVQDLME----TDLYKLLKTQHLSNDHICYFLYQI 131
              + I+         T     D++IV +       +D+ +L + + L    I   LY  
Sbjct: 185 CDSKYIVKYYGSYFKNT-----DLWIVMEYCGAGSVSDIMRL-RNKTLVEREIATILYYT 346

Query: 132 LRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTGFLTEYVATRWY 191
           L+GL Y+HS   +HRD+K  N+LLN     K+ DFG   VA    D        + T ++
Sbjct: 347 LKGLXYLHSRRKIHRDIKAGNILLNNEGHAKLADFG---VAGQLTDTMAKRNTVIGTPYW 517

Query: 192 RAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRP 224
            APE+ +   GY    DIWS+G    EM   +P
Sbjct: 518 MAPEV-IQEIGYDCVADIWSLGITALEMAEGKP 613
>12721
          Length = 821

 Score = 78.6 bits (192), Expect = 3e-15,   Method: Compositional matrix adjust.
 Identities = 56/217 (25%), Positives = 101/217 (46%), Gaps = 7/217 (3%)
 Frame = +1

Query: 29  IGEGAYGMVCSAYDNLNKVRVAIKKISPFEHQTYCQRTLREIKILLRFRHENIIG----- 83
           IGEG+ G+VC A     + ++A+KK+     Q   +    E+ ++  + H NI+      
Sbjct: 112 IGEGSTGIVCIATSRDGR-QMAVKKMD-LRKQQRRELLFNEVVVMRDYHHPNIVEMYNSY 285

Query: 84  -INDIIRAPTIEQMKDVYIVQDLMETD-LYKLLKTQHLSNDHICYFLYQILRGLKYIHSA 141
            +ND           ++++V + ME   L  ++    +    I       L+ L ++H+ 
Sbjct: 286 LVND-----------ELWVVMEFMEGGALTDIVTNNRMDEVQIATVCRACLKALAFLHAN 432

Query: 142 NVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTGFLTEYVATRWYRAPEIMLNSK 201
            V+HRD+K  ++LL+    +K+ DFG       D      L   V T ++ APE+ ++  
Sbjct: 433 GVIHRDIKSDSILLSHDGKVKLXDFGFCAQVTQDLQKRKSL---VGTPYWMAPEV-ISRL 600

Query: 202 GYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHI 238
            Y   +DIWS+G ++ EM+   P F  +  L  +  I
Sbjct: 601 PYGPEVDIWSLGIMVMEMIDAEPPFFNEPPLQAMRRI 711
>09606
          Length = 1300

 Score = 75.9 bits (185), Expect = 2e-14,   Method: Compositional matrix adjust.
 Identities = 59/219 (26%), Positives = 91/219 (41%), Gaps = 19/219 (8%)
 Frame = -3

Query: 113 LLKTQHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVA 172
           L +  HL    I  F   ++ GL YIHS  +L  DL+PS +LL+T+  LK  DFGL++V 
Sbjct: 860 LAQDHHLPETSIRDFGIHLVTGLHYIHSLGILFHDLRPSKVLLDTSGVLKFADFGLSKVE 681

Query: 173 DPDHDHTGFLTEYVATRW-------------------YRAPEIMLNSKGYTKSIDIWSVG 213
             + +   F       +W                   Y APE+   ++    S D+W++G
Sbjct: 680 GENLEELFFKFAEAGDQWNIQSAEEMMKQVPTSGSPTYMAPEVFQGAEPSIMS-DLWALG 504

Query: 214 CILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPW 273
           C+  EM S  P F G+ Y                     I   K  N    LP   KV  
Sbjct: 503 CVFYEMFSGHPPFLGETY--------------------DITKDKVLNKEFPLP---KVKG 393

Query: 274 NRLFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPYLE 312
           +RL      + L+LL+ +L  +  +R+     + H + +
Sbjct: 392 SRLSAKPSPEFLNLLESLLQKDSTRRLSWASLVKHAFWQ 276
>01392
          Length = 1806

 Score = 75.5 bits (184), Expect = 4e-14,   Method: Compositional matrix adjust.
 Identities = 62/203 (30%), Positives = 86/203 (42%), Gaps = 9/203 (4%)
 Frame = -1

Query: 118  HLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLL---LNTTCDLKICDFGLAR--VA 172
            HL        +  I R L ++HS  + HRDLKP N+L   L+    +KICDF LA     
Sbjct: 1803 HLCEREASLVVRHIARALDFLHSKGIAHRDLKPENILCEHLDDVVPVKICDFDLASGISC 1624

Query: 173  DPDHDHTGFLTEYVATRWYRAPEI----MLNSKGYTKSIDIWSVGCILAEMLSNRPIFPG 228
            D D   T  L   V +  Y APE+    + +S  Y K  D+WS+G IL  ML   P F G
Sbjct: 1623 DGDGTKTPELLTPVGSAEYMAPEVVDAWVGDSFSYDKRCDLWSLGIILYIMLCGYPPFYG 1444

Query: 229  KHYLDQLNHILGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNADSKALDLL 288
                 Q     G     +  D   ++    ++     P +    W  +     S A DL+
Sbjct: 1443 -----QCGEDCGWNRGEACHDCQDMLFNSIQDGHYKFPSQE---WTSI----SSSAKDLI 1300

Query: 289  DKMLTFNPHKRIEVEQALAHPYL 311
              +L   P KR      L HP++
Sbjct: 1299 RHLLVREPRKRYSAADVLKHPWI 1231
>06405
          Length = 1965

 Score = 71.6 bits (174), Expect = 5e-13,   Method: Compositional matrix adjust.
 Identities = 63/218 (28%), Positives = 104/218 (47%), Gaps = 7/218 (3%)
 Frame = +1

Query: 29  IGEGAYGMVCSA-YDNLNKVRVAIKKISPFEHQTYCQRTLREIKILLRFRHENIIGINDI 87
           +G G YG V  A +   NK+ VA+K +   E        L E  I+   +H N++ +  +
Sbjct: 283 LGGGQYGDVYEAMWKRYNKI-VAVKTLK--EDTMALNDFLEEAAIMKEMKHPNLVQLLGV 453

Query: 88  -IRAPTIEQMKDVYIVQDLM-ETDLYKLLKTQHLSNDHICYFLY---QILRGLKYIHSAN 142
             R P        YIV + M   +L   L++     +     +Y   QI  G+ Y+ + N
Sbjct: 454 CTREPPF------YIVTEFMPHGNLLDYLRSSTREENGPTALMYMATQIASGMAYLETKN 615

Query: 143 VLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTGFLTEYVATRWYRAPEIMLNSKG 202
            +HRDL   N L+  +  +K+ DFGLAR+   D  +T  +      +W  APE +  ++ 
Sbjct: 616 FIHRDLAARNCLVADSNMVKVADFGLARLMK-DDTYTAHIGAKFPIKWT-APEGLAFNRF 789

Query: 203 YTKSIDIWSVGCILAEMLS-NRPIFPGKHYLDQLNHIL 239
            T+S DIW+ G +L E+ +     +PG   L ++ H+L
Sbjct: 790 STRS-DIWAFGVLLWELATYGMSPYPGVE-LTEVYHLL 897
>28638
          Length = 1458

 Score = 59.7 bits (143), Expect(2) = 7e-13,   Method: Compositional matrix adjust.
 Identities = 37/105 (35%), Positives = 58/105 (55%), Gaps = 7/105 (6%)
 Frame = -1

Query: 127 FLYQILRGLKYIHS--ANVLHRDLKPSNLLLNTTCD-----LKICDFGLARVADPDHDHT 179
           F  Q+   L ++ +   N++H DLKP N+LL   C+     +KI DFG            
Sbjct: 822 FAQQLCTALLFLATPEMNIIHCDLKPENILL---CNPKRSAIKIVDFG------SSCQLG 670

Query: 180 GFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRP 224
             + +Y+ +R+YR+PE++L    Y  +ID+WS+GCIL EM +  P
Sbjct: 669 QRIYQYIQSRFYRSPEVLLGVP-YDLAIDMWSLGCILVEMHTGEP 538

 Score = 31.6 bits (70), Expect(2) = 7e-13,   Method: Compositional matrix adjust.
 Identities = 31/127 (24%), Positives = 47/127 (37%), Gaps = 34/127 (26%)
 Frame = -2

Query: 224 PIFPGKHYLDQLNHILGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPW----NRLFPN 279
           P+F G +  DQ+  I+ +LG P +  L+     K R Y   LP     P     N+ + +
Sbjct: 539 PLFAGSNEFDQMMKIVEVLGVPPRHILD--QAQKTRKYFDLLPDGTYAPKKPRDNKKYKS 366

Query: 280 ADSKAL------------------------------DLLDKMLTFNPHKRIEVEQALAHP 309
             S+ L                              DL+ +ML F+P  RI    AL H 
Sbjct: 365 PSSRKLHEVLGAEKGGPGGRRMGEPGHTVADYLKFKDLILRMLDFDPKTRISPYYALQHN 186

Query: 310 YLEQYYD 316
           +  +  D
Sbjct: 185 FFRKTSD 165

 Score = 35.4 bits (80), Expect = 0.037,   Method: Compositional matrix adjust.
 Identities = 21/52 (40%), Positives = 31/52 (59%), Gaps = 3/52 (5%)
 Frame = -3

Query: 22   RYTNLSYIGEGAYGMVCSAYDNLNKVRVAIKKI---SPFEHQTYCQRTLREI 70
            RY   S IG+G++G V  AYD+ ++ +VAIK I    PF +Q   +  L E+
Sbjct: 1144 RYEIDSLIGKGSFGQVVKAYDHGDQEQVAIKIIKNKKPFLNQAQIEVKLLEL 989
>18484
          Length = 635

 Score = 70.9 bits (172), Expect = 7e-13,   Method: Compositional matrix adjust.
 Identities = 39/122 (31%), Positives = 67/122 (54%), Gaps = 2/122 (1%)
 Frame = +1

Query: 110 LYKLLKTQHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLA 169
           +Y++ +          ++  +I  GL ++H   +++RDLK  N++L++   +KI DFG+ 
Sbjct: 7   MYRIQQEGKFKEPVAAFYAAEIAVGLFFLHDQGIIYRDLKLDNVMLDSEGHIKIADFGMC 186

Query: 170 RVADPDHDHTGFLT--EYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFP 227
           +        TG  T   +  T  Y APEI+L    Y+KS+D W+ G +L EML+ +P F 
Sbjct: 187 K-----EGMTGDATTRTFCGTPDYIAPEIVLYQP-YSKSVDWWAYGVLLFEMLAGQPPFD 348

Query: 228 GK 229
           G+
Sbjct: 349 GE 354
>03294
          Length = 1684

 Score = 70.1 bits (170), Expect = 1e-12,   Method: Compositional matrix adjust.
 Identities = 40/121 (33%), Positives = 64/121 (52%), Gaps = 3/121 (2%)
 Frame = -1

Query: 207  IDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINLKARNYLLSLP 266
            +D+WS+G I A+ML   PIF G   +DQL  I  I+G+P+++       L A N +  L 
Sbjct: 1672 VDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIFRIIGTPTEQTWPEFHKLPAFNGMFPLW 1493

Query: 267  HKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPY---LEQYYDPSDEPIA 323
             + K+  +    + DS  LDL+++ L  +P +RI  ++ L H Y   ++    P D P  
Sbjct: 1492 KEGKL--SETLTDLDSLGLDLIERTLKCDPAQRISCKKMLQHAYFLNVDTSVKPVDVPSP 1319

Query: 324  E 324
            E
Sbjct: 1318 E 1316
>26560
          Length = 398

 Score = 69.3 bits (168), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 36/116 (31%), Positives = 62/116 (53%)
 Frame = -1

Query: 111 YKLLKTQHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLAR 170
           Y L +    +   + ++  +++ GL+++HS  V++RDLKP+N+LL+    ++I D GLA 
Sbjct: 389 YHLSQHGVFTEKEVRFYAAEVMLGLEHMHSRFVVYRDLKPANILLDENGHVRISDLGLAC 210

Query: 171 VADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIF 226
                  H       V T  Y APE+++  + Y  S D +S GC+L ++L     F
Sbjct: 209 DFSKKRPHAS-----VGTHGYMAPEVLMKGQSYDSSADWFSFGCMLYKLLKGHSPF 57
>14420
          Length = 528

 Score = 68.2 bits (165), Expect = 5e-12,   Method: Compositional matrix adjust.
 Identities = 37/140 (26%), Positives = 70/140 (50%), Gaps = 1/140 (0%)
 Frame = +2

Query: 97  KDVYIVQD-LMETDLYKLLKTQHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLL 155
           +++++V + L    L  ++    +    I     + L+ L+++H   V+HRD+K  N+LL
Sbjct: 119 EELWVVMEFLAGGSLTDVVTETCMDEGQIAAVCRECLQALEFLHENQVIHRDIKSDNILL 298

Query: 156 NTTCDLKICDFGLARVADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCI 215
                +K+ DFG      P+      +   V T ++ APE+ +  K Y  ++DIWS+G +
Sbjct: 299 GMDGSVKLTDFGFCAQLSPEQSKRSTM---VGTPYWMAPEV-VTRKQYGPTVDIWSLGVM 466

Query: 216 LAEMLSNRPIFPGKHYLDQL 235
             EM+   P +  ++ L  L
Sbjct: 467 CIEMIEGEPPYLNENPLRAL 526
>12453
          Length = 680

 Score = 66.6 bits (161), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 38/105 (36%), Positives = 52/105 (49%), Gaps = 3/105 (2%)
 Frame = +3

Query: 212 VGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINLKARN---YLLSLPHK 268
           VGCI  EM   RP+FPG    D+L+ I   LG+P+++ L  I    +RN     L+LPH 
Sbjct: 6   VGCIFYEMACGRPLFPGSTVEDELHLIFKTLGTPTEDSLPSI----SRNPDFLALNLPHY 173

Query: 269 NKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPYLEQ 313
                  + P  DS  LDLL K L +N   R+    +L H +   
Sbjct: 174 QGEALITIAPRLDSDGLDLLAKFLKYNAKIRVSAADSLKHSFFNS 308
>13212
          Length = 1067

 Score = 66.2 bits (160), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 53/200 (26%), Positives = 87/200 (43%), Gaps = 5/200 (2%)
 Frame = -1

Query: 119 LSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGL-ARVADPDHD 177
           ++   ICY  +++   L ++H  +V+HRD+K  N+LL    ++K+ DFG+ A+       
Sbjct: 989 MTEAQICYVCHEMCMALDFLHRHHVIHRDIKAGNVLLTIDGEVKLADFGVSAKNTQTQQK 810

Query: 178 HTGFLTEYVATRWYRAPEIM----LNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLD 233
              F    + T ++ APE++    L    Y    DIWS+G  L E     P  P K    
Sbjct: 809 RDTF----IGTPYWMAPEVVLCETLKDTPYDFKADIWSLGVTLIEFAQIEP--PNKEM-- 654

Query: 234 QLNHILGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLT 293
              H + +L          I   K+    L  P K    W +LF        D + K L 
Sbjct: 653 ---HPMRVL----------IKIHKSDPPTLEKPKK----WTKLF-------KDFIAKCLV 546

Query: 294 FNPHKRIEVEQALAHPYLEQ 313
            +P+ R    + L HP++++
Sbjct: 545 KDPNLRPTAAELLEHPFMKR 486
>21808
          Length = 1011

 Score = 66.2 bits (160), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 52/176 (29%), Positives = 86/176 (48%), Gaps = 4/176 (2%)
 Frame = +1

Query: 67  LREIKILLRFRHENIIGINDIIRAPTIEQMKDVYIVQDLMET-DLYKLL--KTQHLSNDH 123
           L E +I+ + RH  +I +  +       Q   ++I+ +LM+   L + L  K + L    
Sbjct: 76  LAEAQIMKKLRHPKLIQLYAVC-----TQDDPIFIITELMKNGSLLEFLQGKGRVLKLPA 240

Query: 124 ICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTGFLT 183
           +     QI  G+ Y+ S N +HRDL   N+L++    +KI DFGLARV   D ++   + 
Sbjct: 241 LIDIGAQIACGMAYLESQNYIHRDLAARNILVSDNNTVKIADFGLARVIKED-EYEARVG 417

Query: 184 EYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLS-NRPIFPGKHYLDQLNHI 238
                +W  APE   N   +T   D+WS G +L E ++  R  +PG    + L+ +
Sbjct: 418 ARFPIKW-TAPEAA-NYNRFTIKSDVWSFGILLTETVTYGRVPYPGMTNAEVLHQV 579
>19761
          Length = 473

 Score = 65.9 bits (159), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 39/110 (35%), Positives = 56/110 (50%), Gaps = 2/110 (1%)
 Frame = -3

Query: 116 TQHLSNDHICYFLYQILRGLKYIHSAN--VLHRDLKPSNLLLNTTCDLKICDFGLARVAD 173
           T  L    I  +L Q    L Y+H+    +LHRDLKP N+ +    D+++ D GLAR   
Sbjct: 441 TAGLPERLIVCWLMQTASALNYMHTHTPVILHRDLKPQNIYVTEKGDVRLGDLGLARKLT 262

Query: 174 PDHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNR 223
              D   F T  V T  Y +PEI L+ + Y    DIWS+GC+  ++   +
Sbjct: 261 GPAD---FATSQVGTIMYLSPEI-LSQQPYNSKSDIWSLGCVFYDITGKK 124
>13066
          Length = 551

 Score = 65.5 bits (158), Expect = 3e-11,   Method: Compositional matrix adjust.
 Identities = 44/148 (29%), Positives = 70/148 (47%), Gaps = 2/148 (1%)
 Frame = +3

Query: 68  REIKILLRFRHENIIGINDII-RAPTIEQMKDVYIVQDLMETDLYKLLK-TQHLSNDHIC 125
           RE+ +L +  H  II I+ I+ R P     K+   ++     DL   ++    +      
Sbjct: 123 RELDLLTKLDHPYIIQIHSILQRXP-----KNFIFMRFAERGDLLTYIQEVGFVKEKQAK 287

Query: 126 YFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTGFLTEY 185
            + YQ+   L Y+HS +V HRDLK  N+LL++  ++K+ DFG A     +         Y
Sbjct: 288 IWFYQMTTALNYLHSYDVAHRDLKCENILLSSHFNVKLADFGFACACITESGEKYMSRTY 467

Query: 186 VATRWYRAPEIMLNSKGYTKSIDIWSVG 213
             +  Y APEI+  +    K  D WS+G
Sbjct: 468 CGSAAYAAPEIVYGAPYAPKVADAWSLG 551
>11185
          Length = 473

 Score = 65.5 bits (158), Expect = 4e-11,   Method: Compositional matrix adjust.
 Identities = 40/134 (29%), Positives = 63/134 (47%), Gaps = 21/134 (15%)
 Frame = +1

Query: 127 FLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTGFLTEYV 186
           F   ++ GL YIHS  +L  DL+PS +LL+T+  LK  DFGL++V   + +   F     
Sbjct: 16  FGIHLVTGLHYIHSLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEA 195

Query: 187 ATRW-------------------YRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIF- 226
             +W                   Y APE+   ++    S D+W++GC+  EM S   +  
Sbjct: 196 GDQWNIQSAEEMMKQVPTSGSPTYMAPEVFQGAEPSIMS-DLWALGCVFYEMFSGSRLSA 372

Query: 227 -PGKHYLDQLNHIL 239
            P   +L+ L  +L
Sbjct: 373 KPSPEFLNLLESLL 414
>30755
          Length = 1137

 Score = 65.1 bits (157), Expect = 4e-11,   Method: Compositional matrix adjust.
 Identities = 36/112 (32%), Positives = 60/112 (53%), Gaps = 6/112 (5%)
 Frame = +2

Query: 118 HLSNDHIC------YFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARV 171
           HLS++ I       ++  +I+  L Y+HS  +++RDLK  NLLL+    +K+ DFGL + 
Sbjct: 2   HLSHERIFTEERTRFYGAEIISALGYLHSQGIIYRDLKLENLLLDKDGHIKVADFGLCK- 178

Query: 172 ADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNR 223
              D  +      +  T  Y APE+ L+   Y +++D W  G ++ EM+  R
Sbjct: 179 --EDITYGRTTKTFCGTPEYLAPEV-LDDNDYGRAVDWWGTGVVMYEMICGR 325
>19094
          Length = 898

 Score = 65.1 bits (157), Expect = 4e-11,   Method: Compositional matrix adjust.
 Identities = 42/118 (35%), Positives = 57/118 (48%)
 Frame = +1

Query: 102 VQDLMETDLYKLLKTQHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDL 161
           V D+M       L+ + L    I   LY  L+GL Y+HS   +HRD+K  N+LLN     
Sbjct: 16  VSDIMR------LRNKTLVEREIATILYYTLKGL*YLHSRRKIHRDIKAGNILLNNEGHA 177

Query: 162 KICDFGLARVADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEM 219
           K+ DFG   VA    D        + T ++ APE+ +   GY    DIWS+G    EM
Sbjct: 178 KLADFG---VAGQLTDTMAKRNTVIGTPYWMAPEV-IQEIGYDCVADIWSLGITALEM 339
>31885
          Length = 529

 Score = 64.3 bits (155), Expect = 7e-11,   Method: Compositional matrix adjust.
 Identities = 43/136 (31%), Positives = 69/136 (50%), Gaps = 6/136 (4%)
 Frame = -2

Query: 97  KDVYIVQDL-METDL-YKLLKTQHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLL 154
           +D+++V DL +  DL Y + +      D + ++L Q+   L Y+ S  ++HRD+KP N+L
Sbjct: 453 EDLFMVVDLFLGGDLRYHMQQEVSFREDCVKFYLCQLALVLDYLRSQKIVHRDIKPDNIL 274

Query: 155 LNTTCDLKICDFGLARVADPDHDHTGFLTEYVATRWYRAPEI----MLNSKGYTKSIDIW 210
           L+      + DF +A   + D       T    TR Y APE+    +   +GY   +D W
Sbjct: 273 LDEQGHCHVTDFNIATQLEDDE----LATSTSGTRPYMAPEVYGVAINERRGYGFPVDWW 106

Query: 211 SVGCILAEMLSNRPIF 226
           S+G  L E+L  R  F
Sbjct: 105 SLGVSLFELLKKRRPF 58
>04852
          Length = 1462

 Score = 64.3 bits (155), Expect = 7e-11,   Method: Compositional matrix adjust.
 Identities = 34/95 (35%), Positives = 53/95 (55%)
 Frame = +1

Query: 127 FLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTGFLTEYV 186
           + +QI RG++++ S   +HRDL   N+L+     LKI DFGL+R  D     +G     +
Sbjct: 340 YAFQIARGMEFLASRKCIHRDLAARNVLVTEEHVLKIADFGLSRTGDYYKKRSG---GRL 510

Query: 187 ATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLS 221
             +W  APE + + + YT   D+WS G +L E+ S
Sbjct: 511 PVKWM-APEALFDMR-YTTKSDVWSFGVVLWEIFS 609
>27546
          Length = 426

 Score = 63.5 bits (153), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 47/148 (31%), Positives = 69/148 (46%), Gaps = 5/148 (3%)
 Frame = -1

Query: 28  YIGEGAYG--MVCSAYDNLNKVRVAIKKISPFEHQTYCQRTLREIKILLRFRHENIIGIN 85
           Y  E  +G  + C   D        +KK  P           RE++IL R  H NII I+
Sbjct: 426 YADESGHGVNLACKIIDKAKAPIDFVKKFFP-----------RELEILTRLDHPNIIQIH 280

Query: 86  DII-RAPTIEQMKDVYIVQDLMETD--LYKLLKTQHLSNDHICYFLYQILRGLKYIHSAN 142
            I+ R P I      +I     E    L  + KT  +       + +Q+ + L+Y+HS +
Sbjct: 279 SILQRGPKI------FIFMRYAEKGDMLSHIKKTGPIDEAQTKVWFFQMAKALQYLHSHD 118

Query: 143 VLHRDLKPSNLLLNTTCDLKICDFGLAR 170
           + HRDLK  N+LL+   ++KI DFG AR
Sbjct: 117 IAHRDLKCENILLSKRLNVKIADFGFAR 34
>18401
          Length = 463

 Score = 62.8 bits (151), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 43/149 (28%), Positives = 74/149 (49%), Gaps = 14/149 (9%)
 Frame = -3

Query: 186 VATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFP---GKHYLDQLNHILGIL 242
           V+TR YRAPE++L   G++   D+WSVGCI+ E+ +   +F     K +L  +  ILG L
Sbjct: 449 VSTRHYRAPEVILEL-GWSHPCDVWSVGCIMFELYTGYTLFQTHDNKEHLAMMERILGSL 273

Query: 243 ------GSPSQEDL-NCIINLKARNYLLSLPHKNKVPWNRLFPNADSK----ALDLLDKM 291
                  +  Q+   +  +++  R+ +     +N  P  R   + ++K      DL+ K+
Sbjct: 272 PYRMAKKTKKQKYFHHGRLDVPERSSMARYVRENTKPLLRYVKDRENKDHQQLFDLMKKL 93

Query: 292 LTFNPHKRIEVEQALAHPYLEQYYDPSDE 320
           L +    R  + QAL HP+   Y+   D+
Sbjct: 92  LAYEASSRYSLLQALQHPFFSPYHHNRDQ 6
>01718
          Length = 959

 Score = 61.6 bits (148), Expect = 5e-10,   Method: Compositional matrix adjust.
 Identities = 53/166 (31%), Positives = 78/166 (46%), Gaps = 5/166 (3%)
 Frame = +3

Query: 67  LREIKILLRFRHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQHLSNDHICY 126
           LRE+++L R +H NI+    +            YI    +E  L K  K + L       
Sbjct: 276 LREVQLLNRLQHANILRFMGVCVHEGQLHALTEYIPSGNLEQLLEK--KDEELPWTQRIQ 449

Query: 127 FLYQILRGLKYIHSANVLHRDLKPSNLLL----NTTCDLKICDFGLA-RVADPDHDHTGF 181
               + RGL Y+HS   +HRDL   N+L+    N      I DFGLA ++ DP  D    
Sbjct: 450 LTLGLARGLDYLHSTRFIHRDLTSKNILIRREDNHGYHAVIADFGLATKIPDP-LDKEKL 626

Query: 182 LTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFP 227
            T  V + ++ APE+ LN   Y +  D++SVG I+ E+ +  P  P
Sbjct: 627 PT--VGSPYWMAPEV-LNGHFYNERADLFSVGIIMCEITARIPADP 755
>07940
          Length = 1336

 Score = 61.6 bits (148), Expect = 5e-10,   Method: Compositional matrix adjust.
 Identities = 37/113 (32%), Positives = 58/113 (51%)
 Frame = -3

Query: 109 DLYKLLKTQHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGL 168
           D+ K+L  + L +     + YQ+ RG++Y+ S   +HRDL   N+L+     LKI DFGL
Sbjct: 371 DMLKMLTPKDLIS-----YAYQVARGMEYLASKQCIHRDLAARNVLVAEEYVLKIADFGL 207

Query: 169 ARVADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLS 221
            R       +       +  +W  APE + + K YT   D+WS G +L E+ +
Sbjct: 206 TRNLQQFDYYRKTTDGRLPVKWM-APEALFDRK-YTSKSDVWSYGVLLWEIFT 54
>00715
          Length = 1788

 Score = 59.7 bits (143), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 50/182 (27%), Positives = 77/182 (42%), Gaps = 29/182 (15%)
 Frame = +1

Query: 76  FRHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQHLSNDHI--------CYF 127
            RH N++    I+ A ++ + +D       +  +    L  Q + NDH            
Sbjct: 97  LRHVNVV---SILGATSLHRFED----GAWLAMEYVGPLNLQTILNDHQQDIDSSMRLSL 255

Query: 128 LYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTG------- 180
             Q+ RGL Y+HS N++H DLKP+N LL     L+I DFG      P     G       
Sbjct: 256 ALQMARGLHYLHSINIVHLDLKPANCLLTRDLKLRIADFGCCHQLTPTGLDMGEREGGMA 435

Query: 181 ------------FLTEYVATRWYRAPEIMLNSKGYTKSI--DIWSVGCILAEMLSNRPIF 226
                       +  E   T  YRAPE++   KG   S+  D++S+G  L +M + +  +
Sbjct: 436 GNELELTPVQGAWKNELAGTLAYRAPELL---KGLQPSVRSDVYSLGITLWQMCTRQGPY 606

Query: 227 PG 228
            G
Sbjct: 607 EG 612
>21079
          Length = 878

 Score = 59.3 bits (142), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 37/106 (34%), Positives = 56/106 (52%), Gaps = 2/106 (1%)
 Frame = +1

Query: 119 LSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLL--NTTCDLKICDFGLARVADPDH 176
           L+     +F+ QI  G+ Y+H+ ++LH DLKP N+L   + +  +KI DFGLAR   P  
Sbjct: 118 LTERDCVHFVRQICSGVGYMHTQSILHLDLKPENVLCVSDNSNQIKIIDFGLARFYKPGD 297

Query: 177 DHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSN 222
                L     T  + APE+ +N      + D+WS+G I   +LS 
Sbjct: 298 S----LQVLFGTPEFIAPEV-VNYDEINFTTDMWSIGVICYILLSG 420
>12786
          Length = 460

 Score = 57.8 bits (138), Expect = 6e-09,   Method: Compositional matrix adjust.
 Identities = 41/133 (30%), Positives = 64/133 (48%), Gaps = 21/133 (15%)
 Frame = -3

Query: 115 KTQHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADP 174
           + Q L    I ++  ++LR +K +H+  V+H DLKP+N +L    +LK+ DFG+A     
Sbjct: 431 QEQGLDRMMIKFYWREMLRAVKALHNEGVIHSDLKPANFML-VAGNLKLIDFGIANTL-- 261

Query: 175 DHDHTGFLTEY-VATRWYRAPEIMLNS--------------------KGYTKSIDIWSVG 213
             D T  L +  V T  Y +PE ++ +                    K   +S D+WS+G
Sbjct: 260 QQDKTSVLKDSRVGTPSYMSPEAIMAACDDSADDSMEEDGHRTKPKYKVGVRS-DVWSLG 84

Query: 214 CILAEMLSNRPIF 226
           CIL  M+  R  F
Sbjct: 83  CILYNMVYGRTPF 45
>27405
          Length = 532

 Score = 57.4 bits (137), Expect = 9e-09,   Method: Compositional matrix adjust.
 Identities = 36/112 (32%), Positives = 59/112 (52%), Gaps = 2/112 (1%)
 Frame = -3

Query: 101 IVQDLMET-DL-YKLLKTQHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTT 158
            + DLM   DL Y L +    +   + ++  +++ GL+++HS  V++RDLKP+N+LL+  
Sbjct: 323 FILDLMNGGDLHYHLSQHGVFTEKEVRFYAAEVMLGLEHMHSRFVVYRDLKPANILLDEN 144

Query: 159 CDLKICDFGLARVADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIW 210
             ++I D GLA        H       V T  Y APE+++  + Y  S D W
Sbjct: 143 GHVRISDLGLACDFSKKKPHAS-----VGTHGYMAPEVLMKGQAYDSSAD-W 6
>03240
          Length = 1683

 Score = 57.4 bits (137), Expect = 9e-09,   Method: Compositional matrix adjust.
 Identities = 59/257 (22%), Positives = 100/257 (38%), Gaps = 53/257 (20%)
 Frame = -3

Query: 23   YTNLSYIGEGAYGMVCSAYDNLNKVRVAIKKISPFEHQTYCQRTLREIKILLRFRHENII 82
            +  +  +G GA+G V     N   +  A+K             TLR+  +L R +  ++ 
Sbjct: 1285 FEKIKTLGVGAFGEVSLCRKNDTGMLYAMK-------------TLRKSDVLKRNQVAHVK 1145

Query: 83   GINDIIRAPTIE-------QMKD---VYIVQDLM-ETDLYKLLKTQHLSNDHIC-YFLYQ 130
               DI+     E         +D   +Y V D +   DL  LL    + ++ +  +++ +
Sbjct: 1144 AERDILAEADNEWVVKLYYSFQDHNYLYFVMDYVPGGDLMGLLIRMEILDEPLARFYVAE 965

Query: 131  ILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTGFLTE------ 184
            +++ ++ +H    +HRD+KP N+L++    +K+ DFGL       H+   +  +      
Sbjct: 964  LVQAIESVHRMGFIHRDIKPDNILIDRNGHIKLTDFGLCTGFRWTHNSKYYQRDGTHARQ 785

Query: 185  -----------------------------------YVATRWYRAPEIMLNSKGYTKSIDI 209
                                                V T  Y APE++    GYT   D 
Sbjct: 784  DSMEVKCQLDEQCQCEILKPLERRRKREQRCLAHSLVGTPNYIAPEVLSRLGGYTSVCDW 605

Query: 210  WSVGCILAEMLSNRPIF 226
            WSVG IL EML   P F
Sbjct: 604  WSVGVILFEMLVGHPPF 554
>18996
          Length = 491

 Score = 56.6 bits (135), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 36/94 (38%), Positives = 52/94 (55%), Gaps = 3/94 (3%)
 Frame = +2

Query: 144 LHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTGFLTEYVATRWYRAPEIMLNSKGY 203
           +HRDL   N+L++ +C +KI DFGLA+ A+ D  + G     +  +WY +PE +   K +
Sbjct: 2   IHRDLAARNILVDRSC-VKISDFGLAQFANADGYYYGISQRDIPIKWY-SPEAIETCK-F 172

Query: 204 TKSIDIWSVGCILAEMLSNRPI---FPGKHYLDQ 234
           +   D+WS G  L EM S   I    PG H L Q
Sbjct: 173 SSYSDVWSYGVTLFEMFSRGEIPNLLPG-HDLTQ 271
>00392
          Length = 668

 Score = 56.2 bits (134), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 47/164 (28%), Positives = 79/164 (48%), Gaps = 5/164 (3%)
 Frame = +3

Query: 64  QRTLREIKILLRFRHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKL-LKTQHLSND 122
           QR   E ++L   +H NI+   D          K + +V +LM +   K  LK     N 
Sbjct: 66  QRFKEEAEMLKELQHPNIVRFFDYWEEHNHRNRKVIILVTELMTSGTLKTYLKRFKKPNV 245

Query: 123 HICY-FLYQILRGLKYIHSAN--VLHRDLKPSNLLLNT-TCDLKICDFGLARVADPDHDH 178
            I   +  Q+L+GL ++H+    V+HRDLK  N+ +   T  +KI D GLA + +     
Sbjct: 246 KILKNWCRQVLKGLYFLHTRTPPVIHRDLKCDNIFITGPTGSVKIGDLGLATLKN----- 410

Query: 179 TGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSN 222
             F    + T  + APE  +  + Y +++D+++ G  + EM S+
Sbjct: 411 QSFAKSVIGTPEFMAPE--MYEEHYDEAVDVYAFGMCMLEMASS 536
>17300
          Length = 480

 Score = 55.8 bits (133), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 39/131 (29%), Positives = 63/131 (48%), Gaps = 12/131 (9%)
 Frame = +1

Query: 131 ILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTGFLTE--YVAT 188
           I  G+  +     +HRDL   N+L+N     K+ DFGL+R  + D     + T+   +  
Sbjct: 1   ISSGMGXLADMGYVHRDLAARNILVNEILVCKVADFGLSREIESDTTEGAYTTKGGKIPV 180

Query: 189 RWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLS--NRPIFPGKHYLDQLNHIL------- 239
           RW  APE +   K +T + D+WS G ++ E++S   RP +   +  D +  +        
Sbjct: 181 RW-TAPEAIAYRK-FTSASDVWSFGVVMWEVMSYGERPYWNWSNQ-DVIKAVEKGYRLPL 351

Query: 240 -GILGSPSQED 249
            G+ GSPS  D
Sbjct: 352 HGLSGSPSSTD 384
>11780
          Length = 1713

 Score = 55.1 bits (131), Expect = 4e-08,   Method: Compositional matrix adjust.
 Identities = 47/192 (24%), Positives = 93/192 (48%), Gaps = 8/192 (4%)
 Frame = +3

Query: 29  IGEGAYGMVCSAYDNLNKVR-VAIKKISPFEHQTYCQRTLREIKILLRFRHENIIGINDI 87
           IG+G +G V   Y  + + + VAIK++   +     Q  L+E  ++   RH+N++ +  +
Sbjct: 621 IGKGDFGDV---YKGMYRGQPVAIKQLKDKDRGE--QSFLQEASVMTSLRHDNLVRLIGV 785

Query: 88  IRAPTIEQMKDVYIVQDLM-ETDLYKLLKTQHLS----NDHICYFLYQILRGLKYIHSAN 142
           +   TI      ++V + M + +L + L+++  S     D I  F       ++Y+ S  
Sbjct: 786 VLGETI------FLVTEFMGKGNLVEYLRSRGRSVITKKDQI-NFATDTCAAMEYLESKR 944

Query: 143 VLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTGFLTEYVATRWYRAPEIMLNSKG 202
           ++HRDL   N+L++     K+ DFGLA+  D       F  ++       APE +  +K 
Sbjct: 945 LVHRDLAARNVLVHDDGKAKVSDFGLAKFGDFSQTSVKFPIKWT------APEALRENKI 1106

Query: 203 Y--TKSIDIWSV 212
           +   + +++W +
Sbjct: 1107H*QVRHVELWHI 1142
>14116
          Length = 1017

 Score = 54.7 bits (130), Expect = 6e-08,   Method: Compositional matrix adjust.
 Identities = 54/204 (26%), Positives = 93/204 (45%), Gaps = 11/204 (5%)
 Frame = -1

Query: 29  IGEGAYGMVCSAYDNL----NKVRVAIKKI---SPFEHQTYCQRTLREIKILLRFRHENI 81
           IG+G +G V   +  L      + VA+K +   +P E +   Q  L+E  I+  F H N+
Sbjct: 612 IGKGNFGCVKRGFLTLPEQKGDILVAVKTLHNNNPREIEL--QSFLQEALIMKDFHHSNV 439

Query: 82  IGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKT---QHLSNDHICYFLYQILRGLKYI 138
           + +  I     ++ M  V ++  +   DL   ++    Q    D I Y +  I RG+ Y+
Sbjct: 438 LTLIGI--CLNLDDMPLV-VLPFMKHGDLLTYIRDDQHQPTIKDLIMYGV-DIARGMDYL 271

Query: 139 HSANVLHRDLKPSNLLLNTTCDLKICDFGLAR-VADPDHDHTGFLTEYVATRWYRAPEIM 197
                +HRDL   N +L+    +K+ DFGLAR + + ++  +      +  +W       
Sbjct: 270 AGLKFVHRDLAARNCMLDEDFHVKVADFGLARDIYEKEYYSSENKKAKLPVKWMALES-- 97

Query: 198 LNSKGYTKSIDIWSVGCILAEMLS 221
           L    Y    D+WS G +L E+L+
Sbjct: 96  LEKGNYDSKTDVWSYGVVLWELLT 25
>26711
          Length = 405

 Score = 54.3 bits (129), Expect = 7e-08,   Method: Compositional matrix adjust.
 Identities = 36/99 (36%), Positives = 56/99 (56%), Gaps = 2/99 (2%)
 Frame = -2

Query: 130 QILRGLKYIHSANVLHRDLKPSNLLL--NTTCDLKICDFGLARVADPDHDHTGFLTEYVA 187
           Q+L  L+++H+  V+H DLKPSNLLL  +    +++ DFGLAR   P  +   FL     
Sbjct: 392 QVLDILQHVHAQGVVHMDLKPSNLLLSGDKLDSVQLIDFGLARKLYPPQET--FLNH--G 225

Query: 188 TRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIF 226
           T  + +PE  L+ K  + + D+W VG +   +LS +  F
Sbjct: 224 TPGFTSPE-ALDVKPISTASDVWGVGVLAYILLSGQSPF 111
>05084
          Length = 1324

 Score = 54.3 bits (129), Expect = 7e-08,   Method: Compositional matrix adjust.
 Identities = 27/95 (28%), Positives = 48/95 (50%), Gaps = 1/95 (1%)
 Frame = +2

Query: 226 FPGKHYLDQLNHILGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLF-PNADSKA 284
            PG   +DQL  I+ +LG+P++E    I  +         P     PW ++F P    +A
Sbjct: 2   LPGDSGVDQLVEIIKVLGTPTREQ---IREMNPNYSEFKFPQIKAHPWTKVFRPRTPPEA 172

Query: 285 LDLLDKMLTFNPHKRIEVEQALAHPYLEQYYDPSD 319
           + L+ ++L + P  RI+  +A AH + ++  DP+ 
Sbjct: 173 IQLVSRLLEYTPSARIQPMEACAHAFFDELRDPAS 277
>21433
          Length = 590

 Score = 53.5 bits (127), Expect(2) = 8e-08,   Method: Compositional matrix adjust.
 Identities = 37/98 (37%), Positives = 53/98 (54%)
 Frame = +2

Query: 127 FLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTGFLTEYV 186
           ++YQ+   L+Y H   V+HRD+KP NLLL    DLKI DFG +      H  +   T   
Sbjct: 182 YIYQLSSALEYCHYRKVIHRDIKPENLLLGLKGDLKIADFGWSV-----HAPSSRRTTMC 346

Query: 187 ATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRP 224
            T  Y  PE M+  K + +++D+WS+G +  E L   P
Sbjct: 347 GTLDYLPPE-MVEGKTHDENVDLWSLGVLCYEFLVGTP 457

 Score = 20.4 bits (41), Expect(2) = 8e-08,   Method: Compositional matrix adjust.
 Identities = 16/52 (30%), Positives = 26/52 (50%), Gaps = 1/52 (1%)
 Frame = +3

Query: 68  REIKILLRFRHENIIGINDIIRAPTIEQMKDVYIVQDLM-ETDLYKLLKTQH 118
           REI+I    RH+NI+ +       T      VY++ +   + +LYK L+  H
Sbjct: 15  REIEIQSHLRHDNILRMFGYFHDKT-----RVYLILEFAPKGELYKELQRCH 155
>26909
          Length = 394

 Score = 53.1 bits (126), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 43/138 (31%), Positives = 63/138 (45%), Gaps = 23/138 (16%)
 Frame = +2

Query: 215 ILAEMLSNRPIF---------PGKHYLDQLNHILGILGSPSQEDLNCI----------IN 255
           I AE+L++ PIF            ++ DQL+ I  ++G P ++D   I           +
Sbjct: 2   IFAELLTSEPIFHCRQEDIKTSNPYHHDQLDRIFNVMGFPQEKDWEDIRRMPEHQQLTKD 181

Query: 256 LKARNY----LLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPYL 311
            K  +Y    L+    K+KV        ADSKA  LL K+LT +P KRI  EQA+  PY 
Sbjct: 182 FKRSSYVNCNLMKYMEKHKV-------KADSKAFHLLQKLLTMDPVKRITSEQAMKDPYF 340

Query: 312 EQYYDPSDEPIAEAPFKF 329
            +   PS +     P  +
Sbjct: 341 LEEPLPSSDVFDSLPIPY 394
>19301
          Length = 712

 Score = 52.4 bits (124), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 44/150 (29%), Positives = 71/150 (47%), Gaps = 4/150 (2%)
 Frame = +2

Query: 24  TNLSYIGEGAYGMVCSAYDNLNKVRVAIKKISPFEHQTYCQRTLREIKI--LLRFRHENI 81
           T+L ++G GA G V      L    VA+KK+          R ++E  I  L +  H NI
Sbjct: 314 TDLEWLGSGAQGAV--FLGKLCAEEVAVKKV----------RDIKETDIRNLRKLNHPNI 457

Query: 82  IGINDI-IRAPTIEQMKDVYIVQDLMETDLYKLLK-TQHLSNDHICYFLYQILRGLKYIH 139
           I    +  +AP         I++      LY++L+  + +    +  +  QI  G+ Y+H
Sbjct: 458 ISFKGVCTQAPCY-----CIIMEYCPYGQLYEVLRDGKEIPPALVLDWSKQIASGMNYLH 622

Query: 140 SANVLHRDLKPSNLLLNTTCDLKICDFGLA 169
           S  ++HRDLK  N+L+     +KI DFG +
Sbjct: 623 SHKIIHRDLKSPNVLVAKNDVVKISDFGTS 712
>28157
          Length = 400

 Score = 49.3 bits (116), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 42/130 (32%), Positives = 62/130 (47%), Gaps = 9/130 (6%)
 Frame = +3

Query: 49  VAIKKISPFEHQTYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQMKDVYIVQDLMET 108
           VA+K+I   + +   +  ++E+K L R  H NI+ +    R         V +V +  E 
Sbjct: 9   VAVKRIESEQEK---KSFMQELKQLSRVSHPNIVCLYGACRD------HPVCLVMEYAEG 161

Query: 109 -DLYKLLKTQ----HLSNDHICYFLYQILRGLKYIHSAN---VLHRDLKPSNLLL-NTTC 159
             LY +L         +  H   +L Q   G++Y+H      ++HRDLKP NLLL     
Sbjct: 162 GSLYNVLHGSGPQPQYTAAHAMNWLLQCALGVEYLHGMKPKALIHRDLKPPNLLLIQCGT 341

Query: 160 DLKICDFGLA 169
            LKICDFG A
Sbjct: 342 KLKICDFGTA 371
>01106
          Length = 878

 Score = 48.9 bits (115), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 44/156 (28%), Positives = 73/156 (46%), Gaps = 14/156 (8%)
 Frame = +3

Query: 14  GQVFDVGPRYTNLSYIGEGAYGMVCSAYDNLNKVRVAIKKISPFEHQTYCQRTLREIKIL 73
           G +F+   RY  +  +G G +  V   +D   K  VA+K +   +H  Y +  L E+K+L
Sbjct: 303 GDLFN--GRYHVIRKLGWGHFSTVWLCWDLTCKRFVALKVVKSAQH--YTETALDEVKLL 470

Query: 74  LRFRHENIIGINDIIRAPTIEQMKDVYI-------VQDLMETDLYKLLKTQHLSN----- 121
              R  ++    D  RA  ++ + D  I       V  + E   Y LLK    SN     
Sbjct: 471 KCVRESDVA---DPARAKCVQLLDDFKISGVNGTHVAMVFEVLGYNLLKLIIRSNYQGIP 641

Query: 122 -DHICYFLYQILRGLKYIHS-ANVLHRDLKPSNLLL 155
             ++   + Q+L GL Y+H+   ++H D+KP N+L+
Sbjct: 642 IHNVKLIIRQVLEGLSYMHAKCRIIHTDIKPENILI 749
>14477
          Length = 493

 Score = 47.8 bits (112), Expect = 6e-06,   Method: Compositional matrix adjust.
 Identities = 39/155 (25%), Positives = 78/155 (50%), Gaps = 5/155 (3%)
 Frame = -1

Query: 29  IGEGAYGMVCSAYDNLN--KVRVAIKKISPFEHQTYCQRTL-REIKILLRFRHENIIGIN 85
           +G G +G V      L+  ++ VAIK +   +     Q  L +E +++ +  H +I+ + 
Sbjct: 466 LGAGNFGSVMKGVCRLDDREIPVAIKVLKNADLDPSVQSELIKEAEVMKKMDHMHIVRLI 287

Query: 86  DIIRAPTIEQMKDVYIVQDLMETD-LYKLL-KTQHLSNDHICYFLYQILRGLKYIHSANV 143
            +    T+       +V +L +   L K L K +HL   +I   ++Q+ +G++Y+ +   
Sbjct: 286 GLCEGETM------MLVLELAKLGPLNKFLPKNKHLPLWNILELMWQVSQGMEYLEANKF 125

Query: 144 LHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDH 178
           +HRDL   N+LL      KI DFG+++    ++++
Sbjct: 124 VHRDLAARNILLCDEHFAKISDFGMSKTLSRENNY 20
>13078
          Length = 773

 Score = 47.4 bits (111), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 32/131 (24%), Positives = 60/131 (45%), Gaps = 14/131 (10%)
 Frame = -1

Query: 200 SKGYTKSIDIWSVGCILAEMLSNRPIFP---GKHYLDQLNHILGIL-------GSPSQED 249
           S G+++  D+WS+GCI+ E+ +   +F     K +L  +  ILG L           +  
Sbjct: 755 SWGWSQPCDVWSIGCIMFELYTGYTLFQTHDNKEHLAMMERILGSLPYRMAKKTKKQKYF 576

Query: 250 LNCIINLKARNYLLSLPHKNKVPWNRLFPNADS----KALDLLDKMLTFNPHKRIEVEQA 305
            +  ++   ++        N  P  R   + D+    +  DL+DKML++    R  + QA
Sbjct: 575 YHGRLDWDEKSSAGRYVRDNVKPLRRYVKDPDNEDHQQLFDLMDKMLSYEVSTRYSLRQA 396

Query: 306 LAHPYLEQYYD 316
           + HP+  + Y+
Sbjct: 395 MRHPFFRKLYE 363
>07291
          Length = 833

 Score = 46.2 bits (108), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 30/101 (29%), Positives = 50/101 (49%)
 Frame = +1

Query: 127 FLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTGFLTEYV 186
           F  QI  G+ Y+    V+HR+L   N ++     L++ D+G+     P   +T   +   
Sbjct: 64  FGRQIADGMAYLQEVKVVHRNLAARNCIVTEDGRLQLSDYGVTGSLFPQSYYTADDSPAR 243

Query: 187 ATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFP 227
               + APE + N    +KS D+W+ G +L E+L+ R I P
Sbjct: 244 DLVKWMAPETIDNFHFSSKS-DVWAFGVVLWELLT-RGITP 360
>00638
          Length = 1595

 Score = 45.4 bits (106), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 29/89 (32%), Positives = 50/89 (56%), Gaps = 1/89 (1%)
 Frame = +2

Query: 69  EIKILLRFRH-ENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQHLSNDHICYF 127
           EIKIL   R   N+I +  I++ P         I + +  TD  +L +T   ++  I ++
Sbjct: 266 EIKILENLRGGTNVITLLAIVKDPV--SRTPALIFEHVNNTDFKQLYQT--FTDYDIRFY 433

Query: 128 LYQILRGLKYIHSANVLHRDLKPSNLLLN 156
           LY++++ L + HS  ++HRD+KPS  L+N
Sbjct: 434 LYELMKALDFCHSMGIMHRDVKPSPPLVN 520
>20640
          Length = 1492

 Score = 45.1 bits (105), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 25/78 (32%), Positives = 38/78 (48%)
 Frame = +1

Query: 144 LHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTGFLTEYVATRWYRAPEIMLNSKGY 203
           +HRDL   N L+     +KI DFGLAR       + G   + +  RW     I+ N   +
Sbjct: 10  VHRDLATRNCLVGHDLVVKISDFGLARSVHSVDYYRGSEHDAIPIRWMPLEAILYNK--F 183

Query: 204 TKSIDIWSVGCILAEMLS 221
           +   D+WS G +L E+ +
Sbjct: 184 STQSDVWSFGVVLWEIFA 237
>07836
          Length = 1478

 Score = 44.3 bits (103), Expect = 7e-05,   Method: Compositional matrix adjust.
 Identities = 47/188 (25%), Positives = 84/188 (44%), Gaps = 17/188 (9%)
 Frame = -1

Query: 49   VAIKKISPFEHQTYCQRTLREIKILLRFRHENIIGI--NDIIRAPTIEQMKDVYIVQDLM 106
            VA+K     E  ++ + T  E+   +  RHENI+G    DI    +  Q+   +++ D  
Sbjct: 1469 VAVKIFFTTEEASWFRET--ELYQTVLLRHENILGFIAADIKGTGSWTQL---FLITDYH 1305

Query: 107  ET-DLYKLLKTQHLSNDHICYFLYQILRGLKYIH--------SANVLHRDLKPSNLLLNT 157
            E   L+  L ++ L +  +    +  + GL ++H           + HRD+K  N+L+  
Sbjct: 1304 ENGSLHDYLLSRVLDSSEMLALAHSAICGLAHLHIEIFGTRGKPAIAHRDIKSKNILVKK 1125

Query: 158  TCDLKICDFGLA-RVADPDHDHTGFLTEYVATRWYRAPEI---MLNSKGYT--KSIDIWS 211
                 I D GLA R     ++          T+ Y APE+   +LN K +   K  D+++
Sbjct: 1124 NGTCCIADLGLAVRYISESNEVDVAPNPRQGTKRYMAPEVLEMLLNVKNFDAFKQADMYA 945

Query: 212  VGCILAEM 219
             G ++ E+
Sbjct: 944  FGLVMWEI 921
>37602
          Length = 804

 Score = 43.9 bits (102), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 25/70 (35%), Positives = 40/70 (57%)
 Frame = -1

Query: 109 DLYKLLKTQHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGL 168
           D+Y +  T  L+   I +   + L+GL Y+H    +HRD+K +N+LL    D+K+ DF  
Sbjct: 252 DIYHV--TGPLTEPQIAFVCRETLKGLHYLHRRGKMHRDIKGANILLTEEGDVKLADF-- 85

Query: 169 ARVADPDHDH 178
            RV+  +H H
Sbjct: 84  WRVSS-NHSH 58
>11404
          Length = 563

 Score = 43.1 bits (100), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 42/144 (29%), Positives = 74/144 (51%), Gaps = 8/144 (5%)
 Frame = +1

Query: 20  GPRYTNLSYIGEGAYGMVCSAYDNLNKVRVAIKKI---SPFEHQTYCQRTLREIKILLRF 76
             RY   S IG+G++G V  AYD+ +  +VAIK I    PF +Q   Q  ++ ++++ R 
Sbjct: 136 ADRYEIDSLIGKGSFGQVVKAYDHTDNEQVAIKIIKNKKPFLNQA--QIEVKLLEMMNRH 309

Query: 77  RHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQH---LSNDHICYFLYQILR 133
             +N   I  + R         + +V +L+  +LY LL+  +   +S +    F  Q+  
Sbjct: 310 DTDNKYYIVRLKRHFMFRSH--LCLVFELLSYNLYDLLRNTNFRGVSLNLTRKFAQQLCT 483

Query: 134 GLKYIHS--ANVLHRDLKPSNLLL 155
            L ++ +   +++H DLKP N+LL
Sbjct: 484 ALLFLATPEMSIIHCDLKPENILL 555
>02638
          Length = 1490

 Score = 42.7 bits (99), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 21/64 (32%), Positives = 34/64 (53%)
 Frame = +1

Query: 181 FLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILG 240
           F  + + T  + APE+ L  + Y ++ D+WSVGC++ EM + RP +      + L  I  
Sbjct: 4   FQGQLLGTIAFMAPEV-LRGESYGRACDVWSVGCVMIEMCTCRPPWNSHDISNHLALIFK 180

Query: 241 ILGS 244
           I  S
Sbjct: 181 IASS 192
>16708
          Length = 1397

 Score = 42.4 bits (98), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 29/118 (24%), Positives = 56/118 (47%), Gaps = 17/118 (14%)
 Frame = -1

Query: 124  ICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARV----ADPDHDHT 179
            +C    Q +  L++IH   V+H D+K  N+L++   + K+ D+G+A++      P   H+
Sbjct: 1088 VCCIAGQXVCALEHIHELGVVHMDVKADNVLVDAHGNCKLTDYGIAQLYKVYPAPTETHS 909

Query: 180  GFLTEYVATRWYRAPEIMLNSKGYTKSID------------IWSV-GCILAEMLSNRP 224
               T    T + R P  M  S+ +++  D            +W++ G +L  +  +RP
Sbjct: 908  SGCTNK-RTFYTRPPATMTPSERFSEEGDGIGTDYFRLGQMLWTLTGAVLLHVWVSRP 738
>37063
          Length = 455

 Score = 42.0 bits (97), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 32/78 (41%), Positives = 40/78 (51%), Gaps = 9/78 (11%)
 Frame = -2

Query: 148 LKPSNLL---LNTTCDLKICDFGLARVADPDHDHTGF--LTEYVATRWYRAPEI----ML 198
           LKP N+L   L+    LKICDF LA   + D D T    L   V +  Y APE+    + 
Sbjct: 454 LKPENILCEHLDEVVPLKICDFDLASGINCDGDGTKTPELLTPVGSAEYMAPEVVDAWVG 275

Query: 199 NSKGYTKSIDIWSVGCIL 216
            S  Y K  D+WS+G IL
Sbjct: 274 ESFSYDKRCDMWSLGIIL 221
>22005
          Length = 873

 Score = 42.0 bits (97), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 34/95 (35%), Positives = 47/95 (49%)
 Frame = +1

Query: 126 YFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTGFLTEY 185
           Y   QI  G+ Y+   + +HRDL    +   TT    I DFGLAR       + G   + 
Sbjct: 454 YISQQISAGMAYLAQKDYVHRDLATRTVXSRTT-*S*ISDFGLARSVHSVDYYRGSEQDA 630

Query: 186 VATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEML 220
           +  RW    E +L SK  T+S D+WS G +L E+L
Sbjct: 631 IPIRWM-PLEAILYSKFSTQS-DVWSFGVVLWEIL 729
>16003
          Length = 926

 Score = 40.8 bits (94), Expect = 8e-04,   Method: Compositional matrix adjust.
 Identities = 33/93 (35%), Positives = 46/93 (49%)
 Frame = -1

Query: 219 MLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFP 278
           +L   P  PG   LDQL  I  +LG+P++ +   + +L   +Y+    H  K P   +F 
Sbjct: 926 LLIRLPFLPGDTDLDQLGKIFNMLGTPTETEWPAVTSLP--DYI-QFKHCQKQPLKEIFT 756

Query: 279 NADSKALDLLDKMLTFNPHKRIEVEQALAHPYL 311
            A    L+LLDK+L  NP  R    QAL  PY 
Sbjct: 755 AAGDDLLELLDKLLAMNPLHRCTATQALKMPYF 657
>29360
          Length = 363

 Score = 40.4 bits (93), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 32/121 (26%), Positives = 54/121 (44%), Gaps = 3/121 (2%)
 Frame = +3

Query: 38  CSAYDNLNKVRVAIKKISPFEHQTYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQMK 97
           C  +       VAIK +    H +Y ++   E+ IL R   E+    N +      +   
Sbjct: 3   CKCWKKGTSEIVAIKILK--NHPSYARQGQIEVSILQRLSQESADDYNFVRAFECFQHKN 176

Query: 98  DVYIVQDLMETDLYKLLKT---QHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLL 154
              +V +++E +LY  LK    Q L   +I     Q+L  L+ +    ++H DLKP N++
Sbjct: 177 HTCLVFEMLEQNLYDFLKQNKFQPLPLKYIRPITQQVLTALRKLKQLGLIHADLKPENIM 356

Query: 155 L 155
           L
Sbjct: 357 L 359
>32359
          Length = 928

 Score = 39.7 bits (91), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 38/152 (25%), Positives = 68/152 (44%), Gaps = 10/152 (6%)
 Frame = -1

Query: 23  YTNLSYIGEGAYGMVCSAYDNLNKVRVAIKKI---SPFEHQTYCQRTLREIKILLRFRHE 79
           YT+   IG G++G+V  A        VAIKK+     F++        RE++I+ +  H+
Sbjct: 424 YTDAKVIGNGSFGVVYQAKLVDTSELVAIKKVLQDKRFKN--------RELQIMRKLEHQ 269

Query: 80  NIIGINDIIRAPTIEQMKDVYI--VQDLMETDLYKLLKTQHLSND-----HICYFLYQIL 132
           NI+ +     +   E+  +V++  V + +   +Y++ +    S       +I  ++YQ+ 
Sbjct: 268 NIVKLKFFFYSSG-EKKDEVFLNLVLEYVPETVYRVARHYSKSKQTIPILYIKLYMYQLF 92

Query: 133 RGLKYIHSANVLHRDLKPSNLLLNTTCDLKIC 164
           R L YIH           S   +  T  LK C
Sbjct: 91  RSLAYIH-----------SQACVTATSSLKTC 29
>20559
          Length = 430

 Score = 39.3 bits (90), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 22/71 (30%), Positives = 37/71 (52%), Gaps = 1/71 (1%)
 Frame = -2

Query: 22  RYTNLSYIGEGAYGMVCSAYDNLNKVRVAIKKIS-PFEHQTYCQRTLREIKILLRFRHEN 80
           +Y  L  IGEG YG V  A +      VA+K++    + +      LREI +L   +H N
Sbjct: 372 KYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKHRN 193

Query: 81  IIGINDIIRAP 91
           I+ ++D++ + 
Sbjct: 192 IVRLHDVLHSE 160
>17975
          Length = 449

 Score = 39.3 bits (90), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 32/127 (25%), Positives = 63/127 (49%), Gaps = 5/127 (3%)
 Frame = +3

Query: 48  RVAIKKISPFEHQTYCQRTL-REIKILLRFRHENIIGINDIIRAPTIEQMKDVYIVQDLM 106
           +VA+K I   +     +  L +E++ +   +H N++ + ++I   T      +Y++ +L 
Sbjct: 48  KVAVKVIDKTKLDEVSRSHLFQEVRCMKLVQHPNVVRLYEVIDTQT-----KLYLILELG 212

Query: 107 ET-DLYKLL--KTQHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDL-K 162
           +  D+Y  +   +  L       +  QI+  + Y H  +V+HRDLKP N++      L K
Sbjct: 213 DGGDMYDYIMRHSGGLEEKLAKRYFRQIVEAISYCHKLHVVHRDLKPENVVFFEKPGLVK 392

Query: 163 ICDFGLA 169
           + DFG +
Sbjct: 393 LTDFGFS 413
>12672
          Length = 773

 Score = 38.1 bits (87), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 24/90 (26%), Positives = 45/90 (50%), Gaps = 1/90 (1%)
 Frame = +3

Query: 134 GLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHT-GFLTEYVATRWYR 192
           G++Y++    +HRD+K +N+LL++    K+ DF     A      T    +  + T  Y 
Sbjct: 27  GIQYLNDNGHVHRDIKTANILLDSEYTAKVGDFATVVSAPSGEGKTVQNASVVIGTAAYL 206

Query: 193 APEIMLNSKGYTKSIDIWSVGCILAEMLSN 222
           APE +      +  +D +S G +L E+++ 
Sbjct: 207 APEAI--HFDVSTKLDSYSFGVVLLEVITG 290
>21800
          Length = 855

 Score = 37.7 bits (86), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 33/110 (30%), Positives = 53/110 (48%), Gaps = 14/110 (12%)
 Frame = +2

Query: 60  QTYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQMKDVYI-------VQDLMETDLYK 112
           Q Y +  L EIK+L   R+ +     D  R  +++ + D  I       V  + E   Y 
Sbjct: 416 QHYTETALDEIKLLKCVRNSDE---TDPAREKSVQLLDDFKISGVNGTHVCMVFEVLGYN 586

Query: 113 LLKTQHLSN------DHICYFLYQILRGLKYIHS-ANVLHRDLKPSNLLL 155
           LLK    SN       ++   + Q+L GL Y+H+  N++H D+KP N+L+
Sbjct: 587 LLKLIIRSNYQGIPVHNVKLIIRQVLEGLNYLHAKCNIIHTDIKPENILI 736
>18481
          Length = 437

 Score = 37.4 bits (85), Expect = 0.009,   Method: Compositional matrix adjust.
 Identities = 21/44 (47%), Positives = 27/44 (61%), Gaps = 3/44 (6%)
 Frame = -1

Query: 130 QILRGLKYIHSANVLHRDLKPSNLL--LNTTCD-LKICDFGLAR 170
           Q+L  L++IH    +HRDLKP N L  L   C  L I DFGL++
Sbjct: 173 QLLSRLEFIHQKCFIHRDLKPDNFLMGLGRHCHRLYIIDFGLSK 42
>17253
          Length = 483

 Score = 37.0 bits (84), Expect = 0.012,   Method: Compositional matrix adjust.
 Identities = 15/51 (29%), Positives = 29/51 (56%)
 Frame = -1

Query: 127 FLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHD 177
           F   + RG+ ++ +  ++HRD+   N+L++     K+ DFGL+R     +D
Sbjct: 195 FALHVARGMAHVANNKIVHRDVAARNVLISERNVCKVSDFGLSRRVGDQND 43
>20152
          Length = 445

 Score = 35.8 bits (81), Expect = 0.025,   Method: Compositional matrix adjust.
 Identities = 29/118 (24%), Positives = 48/118 (40%)
 Frame = +1

Query: 194 PEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCI 253
           PEI+L       ++D+WS+G IL  ++     F   +  + L  I+           +C 
Sbjct: 1   PEILLGDSYDAPAVDVWSLGVILYMLVVGEAPFQEANDSETLTMIM-----------DC- 144

Query: 254 INLKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPYL 311
                         + ++P     P+   K  DL++KML   P  R  +   LAHP+L
Sbjct: 145 --------------RYQIP-----PHISHKCQDLIEKMLQREPVDRASLPHILAHPWL 261
>18663
          Length = 600

 Score = 35.0 bits (79), Expect = 0.048,   Method: Compositional matrix adjust.
 Identities = 35/136 (25%), Positives = 55/136 (40%), Gaps = 6/136 (4%)
 Frame = +2

Query: 183 TEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGIL 242
           + +  T  Y APEI L  + Y  S+D W++G +L EML+ R  F           I G  
Sbjct: 2   STFCGTPNYIAPEI-LRGEDYGFSVDWWALGVLLYEMLAGRSPF----------DIAGAS 148

Query: 243 GSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEV 302
            +P Q            +YL  +  +  +   R+  +   KA  +L   L  NP  R+  
Sbjct: 149 ENPDQ---------NTEDYLFQVILEKTI---RIPRSLSVKAASVLKGFLNKNPADRLGC 292

Query: 303 EQALA------HPYLE 312
            +  A      HP+ +
Sbjct: 293 HRESAFMDIVNHPFFK 340
>15931
          Length = 447

 Score = 33.5 bits (75), Expect = 0.12,   Method: Compositional matrix adjust.
 Identities = 15/39 (38%), Positives = 24/39 (61%), Gaps = 1/39 (2%)
 Frame = +1

Query: 279 NADSKAL-DLLDKMLTFNPHKRIEVEQALAHPYLEQYYD 316
           N D + L DL+DKML++    R  + QA+ HP+  + Y+
Sbjct: 55  NEDHQQLFDLMDKMLSYEVSTRYSLRQAMRHPFFRKLYE 171
>26009
          Length = 886

 Score = 33.5 bits (75), Expect = 0.14,   Method: Compositional matrix adjust.
 Identities = 12/31 (38%), Positives = 22/31 (70%)
 Frame = +3

Query: 127 FLYQILRGLKYIHSANVLHRDLKPSNLLLNT 157
            + Q++  L ++HS  ++HRD+KP N+L+ T
Sbjct: 726 VMKQLVSALDFMHSKQLVHRDIKPENVLILT 818
>16350
          Length = 1108

 Score = 32.3 bits (72), Expect = 0.28,   Method: Compositional matrix adjust.
 Identities = 15/33 (45%), Positives = 21/33 (63%), Gaps = 1/33 (3%)
 Frame = +3

Query: 281 DSKAL-DLLDKMLTFNPHKRIEVEQALAHPYLE 312
           D+KA  D L  ML F+P +R    Q+L HP+L+
Sbjct: 744 DAKAFADFLAPMLEFDPEQRATAAQSLQHPWLK 842
>20513
          Length = 405

 Score = 32.3 bits (72), Expect = 0.28,   Method: Compositional matrix adjust.
 Identities = 15/33 (45%), Positives = 21/33 (63%), Gaps = 1/33 (3%)
 Frame = -1

Query: 281 DSKAL-DLLDKMLTFNPHKRIEVEQALAHPYLE 312
           D+KA  D L  ML F+P +R    Q+L HP+L+
Sbjct: 300 DAKAFADFLAPMLEFDPEQRATAAQSLQHPWLK 202
>36481
          Length = 806

 Score = 32.3 bits (72), Expect = 0.29,   Method: Compositional matrix adjust.
 Identities = 29/130 (22%), Positives = 55/130 (42%), Gaps = 4/130 (3%)
 Frame = +2

Query: 30  GEGAYGMVCSAYDNLNKVRVAIKKISPFEHQTYCQRTLREIKILLRFRHENIIGINDIIR 89
           GEG +G V    D L    +A+K I   +   Y +    EI +L + R ++    +  ++
Sbjct: 389 GEGTFGKVVQCKDLLKGDDIALKIIKNVD--KYREAAKLEINVLEKLREKDPHAKHMCVQ 562

Query: 90  A-PTIEQMKDVYIVQDLMETDLYKLLKTQHLSN---DHICYFLYQILRGLKYIHSANVLH 145
                +    V I   ++   ++  LK         + + +  YQ+   + ++H   + H
Sbjct: 563 MLDWFDYHGHVCISFHMLGLSVFDFLKDNSYGAYPIEQVRHISYQLCYAVNFLHENQLTH 742

Query: 146 RDLKPSNLLL 155
            DLKP N+L 
Sbjct: 743 TDLKPENILF 772
>24241
          Length = 413

 Score = 31.2 bits (69), Expect = 0.71,   Method: Compositional matrix adjust.
 Identities = 21/66 (31%), Positives = 33/66 (50%), Gaps = 2/66 (3%)
 Frame = -2

Query: 25  NLSYIGEGAYGMVCSAYDNLNKVRVAIKKISPFEHQTYC-QRTLREIKILLRFRH-ENII 82
            LS IGEG YG+V          ++A+KKI     +       +REI +L   RH + ++
Sbjct: 331 RLSKIGEGTYGVVYKCRHRATGRKLAMKKIRLRGSEDGVPSSAIREIAMLRELRHTQXLV 152

Query: 83  GINDII 88
            + D+I
Sbjct: 151 CLEDVI 134
>35032
          Length = 465

 Score = 30.8 bits (68), Expect = 0.86,   Method: Compositional matrix adjust.
 Identities = 12/26 (46%), Positives = 19/26 (73%)
 Frame = +3

Query: 286 DLLDKMLTFNPHKRIEVEQALAHPYL 311
           DL+ ++L ++P KR+    ALAHP+L
Sbjct: 147 DLVKRLLNYDPSKRLTPXXALAHPFL 224
>17011
          Length = 1371

 Score = 29.3 bits (64), Expect = 2.4,   Method: Compositional matrix adjust.
 Identities = 12/26 (46%), Positives = 19/26 (73%)
 Frame = +1

Query: 286 DLLDKMLTFNPHKRIEVEQALAHPYL 311
           DL+  ++TFNP  R+  + AL+HP+L
Sbjct: 1   DLILDVVTFNPDHRLTPDLALSHPFL 78
>02980
          Length = 3325

 Score = 28.1 bits (61), Expect = 5.7,   Method: Compositional matrix adjust.
 Identities = 13/47 (27%), Positives = 27/47 (57%), Gaps = 5/47 (10%)
 Frame = -2

Query: 121  NDHICYF-----LYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLK 162
            +D + YF     +++I   + Y+H +N  HRD++  +++   +C LK
Sbjct: 1701 HDQLFYFGVGEKVFRIFGFVFYVHPSNNHHRDIRLEHVMFVISCKLK 1561
>07988
          Length = 1131

 Score = 27.7 bits (60), Expect = 6.7,   Method: Compositional matrix adjust.
 Identities = 10/27 (37%), Positives = 17/27 (62%)
 Frame = +3

Query: 255 NLKARNYLLSLPHKNKVPWNRLFPNAD 281
           ++++R++ LSLP    VPW   F + D
Sbjct: 876 HIESRHFFLSLPFPCTVPWRNTFASPD 956
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|9910550|ref|NP_064335.1| Sec11-like 1 [Mus musculus]
         (179 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

08585                                                                 165   7e-42
28671                                                                  31   0.23 
>08585
          Length = 2828

 Score =  165 bits (418), Expect = 7e-42,   Method: Compositional matrix adjust.
 Identities = 79/103 (76%), Positives = 86/103 (83%)
 Frame = +3

Query: 77   IRVGEIVVFRIEGREIPIVHRVLKIHEKQDGHIKFLTKGDNNAVDDRGLYKQGQHWLEKK 136
            I  GEIVVF++EGR+IPIVHRVLKIHEK+DG +KFLTKGDNN+VDDRGLY  GQ WLEKK
Sbjct: 1965 ITAGEIVVFKVEGRDIPIVHRVLKIHEKEDGSVKFLTKGDNNSVDDRGLYAPGQFWLEKK 2144

Query: 137  DVVGRARGFVPYIGIVTILMNDYPKFKYAXXXXXXXXXXXHRE 179
            DVVGRARGFVPY+GIVTILMNDYPKFKYA           HRE
Sbjct: 2145 DVVGRARGFVPYVGIVTILMNDYPKFKYAILVCLGIFVLVHRE 2273
>28671
          Length = 1156

 Score = 31.2 bits (69), Expect = 0.23,   Method: Compositional matrix adjust.
 Identities = 18/73 (24%), Positives = 32/73 (43%), Gaps = 4/73 (5%)
 Frame = +2

Query: 89  GREIPIVHRVLKIHEKQDGHIKFLTKGDNNAVDD----RGLYKQGQHWLEKKDVVGRARG 144
            R   +V  +  ++     H       +N+A  D    +  ++ G+  +EKK +  RARG
Sbjct: 620 ARPCRLVQHMAAVYASIQDHQTAFKMAENSARLDPTYHKPYWRLGKGLVEKKKLRKRARG 799

Query: 145 FVPYIGIVTILMN 157
           F P  G+  +  N
Sbjct: 800 FCPAWGVTVLTAN 838
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|28916673|ref|NP_766184.1| Sec24 related gene family,
member C [Mus musculus]
         (1096 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

30039                                                                 168   9e-42
36546                                                                 100   2e-21
27412                                                                  71   2e-12
>30039
          Length = 404

 Score =  168 bits (426), Expect = 9e-42,   Method: Compositional matrix adjust.
 Identities = 77/126 (61%), Positives = 102/126 (80%)
 Frame = +1

Query: 831 LNCCTQLADLYRNCETDTLINYMAKFAYRAVLNSPVKTVRDTLITQCAQILACYRKNCAS 890
            NCCTQ+ADL+R+CE DTL+N++AK A R  LN   K VR+ ++ + +QILACYRKNCA+
Sbjct: 1   FNCCTQMADLFRSCELDTLVNFLAKQAIRQTLNQNPKFVREHIMNEVSQILACYRKNCAN 180

Query: 891 PSSAGQLILPECMKLLPVYLNCVLKSDVLQPGAEVTTDDRAYVRQLVSSMDVAETNVFFY 950
           PSSAGQLI+PECMKLLP+Y NCV+KSD +Q G+E++TDDR+Y+  L+++MDV  +NV   
Sbjct: 181 PSSAGQLIVPECMKLLPLYANCVIKSDGIQGGSEISTDDRSYLMHLINAMDVHTSNVSL- 357

Query: 951 PRLLPL 956
           PRLLP 
Sbjct: 358 PRLLPF 375
>36546
          Length = 801

 Score =  100 bits (250), Expect = 2e-21,   Method: Composition-based stats.
 Identities = 42/71 (59%), Positives = 57/71 (80%)
 Frame = +3

Query: 1026 LDNPLSKKVRGLIDSLRAQRMRYMKLIVVKQEDKLEMLFKHFLVEDKSLSGGASYVDFLC 1085
            L+N  S+K+R ++D +R +R RY+KL +V+Q DKLE  F HFLVEDK ++G +SYVDFLC
Sbjct: 30   LENEASRKLRDMVDKIRQERARYLKLTIVRQRDKLEPWFNHFLVEDKGMNGSSSYVDFLC 209

Query: 1086 HMHKEIRQLLS 1096
            H+HKEIR LL+
Sbjct: 210  HIHKEIRNLLN 242
>27412
          Length = 384

 Score = 71.2 bits (173), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 41/128 (32%), Positives = 63/128 (49%)
 Frame = +2

Query: 603 LLDQIPEMFADTRETETVFAPVIQAGMEALKAAECAGKLFLFHTSLPIAEAPGKLKNRDD 662
           LL Q+P +F D  ET       +QA  + + +    G++ +  T+LP    PG L+NR+ 
Sbjct: 5   LLTQLPTLFEDNHETGNALGTALQAAFKLMTST--GGRVTVMQTTLPTV-GPGSLENREA 175

Query: 663 RKLINTDKEKTLFQPQTGTYQTLAKECVAQGCCVDLFLFPNQYVDVATLSVVPQLTGGSV 722
                +     L  P +  Y+ LA +C AQ   VDLF+   QY D+AT+S + + + G V
Sbjct: 176 NSKAASLNSAYL-GPSSDFYKKLALDCSAQQIAVDLFMLNGQYADIATVSCISKFSAGCV 352

Query: 723 YKYACFQV 730
             Y  F  
Sbjct: 353 QYYPSFHT 376
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|21313668|ref|NP_082253.1| RIKEN cDNA 2310001A20 [Mus
musculus]
         (415 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

22612                                                                 166   1e-41
25870                                                                  75   5e-14
09471                                                                  30   1.3  
15605                                                                  30   1.5  
>22612
          Length = 615

 Score =  166 bits (420), Expect = 1e-41,   Method: Compositional matrix adjust.
 Identities = 87/205 (42%), Positives = 121/205 (59%)
 Frame = +2

Query: 153 GIRAGPNGTLFVVDAYKGLFEVNPQKRSVKLLLSSETPIEGKKMSFVNDLTVTRDGRKIY 212
           G+R    G L V DAY G+F+VN     V  LLSSE P+ GK    +ND+    DG  IY
Sbjct: 2   GMRLDRAGYLLVADAYLGIFKVNVATGDVHRLLSSEEPMAGKLPKLLNDIEEGPDG-TIY 178

Query: 213 FTDSSSKWQRRDYLLLVMEATDDGRLLEYDTVTKEVKVLLDQLQFPNGVQLSPEEDFVLV 272
           FTDSS++WQR      VMEA   GRLL +D  T+ +  ++  L F NG+ ++ ++  +LV
Sbjct: 179 FTDSSTRWQRYQNRHCVMEAESSGRLLAFDPETQXLHEVMSDLAFANGIAVAYDKTHILV 358

Query: 273 AETTMARIRRVYVSGLMKGGADMFVENMPGFPDNIRPSSSGGYWVAAATIRANPGFSMLD 332
            ETT ARI R Y+SG  KG  D+F +N+PG PDNIR S  G YWV  A +R     S+ D
Sbjct: 359 VETTKARIWRYYISGPKKGEXDIFADNLPGIPDNIRRSGRGTYWVGMAIVRHADKPSLSD 538

Query: 333 FLSDKPFIKRMIFKMFSQETVMKFV 357
             + +P+++ +I K+F    ++K  
Sbjct: 539 IAAPRPWVRSLIMKVFLPGMILKIC 613
>25870
          Length = 420

 Score = 75.1 bits (183), Expect = 5e-14,   Method: Compositional matrix adjust.
 Identities = 46/138 (33%), Positives = 75/138 (54%), Gaps = 7/138 (5%)
 Frame = +2

Query: 237 RLLEYD----TVTKEVKVLLDQLQFPNGVQLSPEE-DFVLVAETTMARIRRVYV--SGLM 289
           R+L+YD       K V  ++  L FPNG+Q++P+   F+LV E T A+I ++++  +  +
Sbjct: 2   RILKYDPRVMDPAKRVTEVVGNLAFPNGIQIAPDGVSFLLVGEGTRAKILKIWIDPTSSL 181

Query: 290 KGGADMFVENMPGFPDNIRPSSSGGYWVAAATIRANPGFSMLDFLSDKPFIKRMIFKMFS 349
            G  D F  N+PG  DNIR S  G  WV  + +R +    +LD   D+P  KR +  +  
Sbjct: 182 YGRIDDFATNLPGIVDNIRLSPRGTLWVGVSQVRHSGLKHVLDQYGDQPN-KRGVLVLLV 358

Query: 350 QETVMKFVPRYSLVLEVS 367
           +  V    P+Y + LE++
Sbjct: 359 KNNVRFDKPKYGMALELN 412
>09471
          Length = 1761

 Score = 30.4 bits (67), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 21/66 (31%), Positives = 34/66 (51%), Gaps = 2/66 (3%)
 Frame = +1

Query: 343 MIFKMFSQETVMKFVPRYSLVLEVSDSGAFRRSLH--DPDGQVVTYVSEAHEHDGYLYLG 400
           + F++FSQE      P+ S+  +VS SG+FR+S H  D  G  + Y+       G  + G
Sbjct: 364 LWFELFSQELSDFLHPQVSVDHQVSLSGSFRQS-HGLDVSGGHIAYIHHGKVQLGARWHG 540

Query: 401 SFRSPF 406
           +F+   
Sbjct: 541 TFQQSL 558
>15605
          Length = 1346

 Score = 30.4 bits (67), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 10/26 (38%), Positives = 18/26 (69%)
 Frame = -1

Query: 278  ARIRRVYVSGLMKGGADMFVENMPGF 303
            +R+ + Y+SG ++GG D F + +P F
Sbjct: 1055 SRVLKTYISGFLEGGDDNFEKQLPEF 978
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|21489933|ref|NP_036082.1| mitogen activated protein
kinase 3 [Mus musculus]
         (380 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

14126                                                                 166   1e-41
01060                                                                 164   4e-41
29581                                                                 153   1e-37
01756                                                                 148   4e-36
01707                                                                 140   7e-34
04591                                                                 131   4e-31
04138                                                                 115   4e-26
32000                                                                 114   5e-26
31489                                                                 104   7e-23
18287                                                                  90   1e-18
28638                                                                  59   1e-17
13592                                                                  87   2e-17
01966                                                                  86   3e-17
03508                                                                  84   8e-17
23319                                                                  84   1e-16
15910                                                                  82   2e-16
18921                                                                  76   2e-14
00300                                                                  75   3e-14
01392                                                                  75   5e-14
09606                                                                  72   5e-13
12721                                                                  71   7e-13
13212                                                                  70   1e-12
06405                                                                  70   1e-12
18484                                                                  70   1e-12
26560                                                                  70   1e-12
03294                                                                  69   4e-12
01718                                                                  67   8e-12
03240                                                                  67   9e-12
14420                                                                  67   1e-11
19761                                                                  67   2e-11
21808                                                                  66   3e-11
04852                                                                  65   5e-11
19094                                                                  65   6e-11
13066                                                                  64   8e-11
12453                                                                  64   1e-10
30755                                                                  64   1e-10
11185                                                                  64   1e-10
31885                                                                  62   3e-10
07940                                                                  62   4e-10
27546                                                                  61   9e-10
00715                                                                  60   2e-09
21079                                                                  59   2e-09
18401                                                                  59   4e-09
27405                                                                  58   6e-09
12786                                                                  58   7e-09
00392                                                                  57   9e-09
14116                                                                  57   9e-09
11780                                                                  57   2e-08
18996                                                                  56   2e-08
26909                                                                  56   3e-08
05084                                                                  56   3e-08
17300                                                                  54   8e-08
19301                                                                  54   9e-08
26711                                                                  54   1e-07
21433                                                                  54   1e-07
28157                                                                  51   9e-07
01106                                                                  50   1e-06
16708                                                                  49   2e-06
07291                                                                  49   4e-06
20640                                                                  46   2e-05
11404                                                                  46   3e-05
00638                                                                  45   4e-05
14477                                                                  45   5e-05
13078                                                                  44   8e-05
07836                                                                  44   1e-04
02638                                                                  43   2e-04
22005                                                                  42   4e-04
37602                                                                  42   5e-04
32359                                                                  42   6e-04
20559                                                                  40   0.002
17253                                                                  39   0.002
37063                                                                  39   0.002
17975                                                                  39   0.004
12672                                                                  37   0.010
21800                                                                  37   0.011
18481                                                                  37   0.013
29360                                                                  36   0.021
16003                                                                  36   0.032
18663                                                                  35   0.047
35032                                                                  35   0.060
26009                                                                  35   0.064
20152                                                                  34   0.11 
16350                                                                  33   0.20 
36481                                                                  33   0.21 
20513                                                                  33   0.22 
15931                                                                  32   0.42 
17011                                                                  32   0.44 
11529                                                                  31   0.95 
01377                                                                  30   2.1  
10464                                                                  29   2.8  
24241                                                                  29   4.1  
29472                                                                  28   5.9  
02980                                                                  28   6.4  
02357                                                                  28   6.6  
04799                                                                  27   9.6  
>14126
          Length = 1265

 Score =  166 bits (421), Expect = 1e-41,   Method: Compositional matrix adjust.
 Identities = 107/303 (35%), Positives = 160/303 (52%), Gaps = 8/303 (2%)
 Frame = +3

Query: 42  RYTQLQYIGEGAYGMVSSAYDHVRKTR-VAIKKIS-PFEHQTYCQRTLREIQILLR---F 96
           +Y ++  IG GAYG V  A D   +   VA+K+I      +      +REI +L +   +
Sbjct: 192 KYEEVAVIGNGAYGTVYKARDLRNQGEFVAMKRIRLNNTEEGMPMMAIREISMLKQLEQY 371

Query: 97  RHENVIGIRDILRAPTLEAMRDVYIVQDLMETDLYKLLK---SQQLSNDHICYFLYQILR 153
            H NV+ + D+      +    + +V + +E DL   L    S  L  D I   + Q+L 
Sbjct: 372 EHPNVVRLLDVSHNTITDREIRLNLVFEYIEHDLATYLAKCPSPGLGPDRIKDLMLQLLN 551

Query: 154 GLKYIHSANVLHRDLKPSNLLINTTCDLKICDFGLARIADPEHDHTGFLTEYVATRWYRA 213
           G+ ++HS  ++HRDLKP NLLI+    LK+ DFGLARI    +     LT  V T WYR+
Sbjct: 552 GVDFLHSNRIVHRDLKPQNLLISKDGRLKLADFGLARI----YSFHMALTTVVVTLWYRS 719

Query: 214 PEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCI 273
           PE+++ ++ Y  S+DIWS GCI AE+ + R +F G    DQL  I  ++G P   D    
Sbjct: 720 PEVLMQAE-YGTSVDIWSCGCIFAELFTRRALFKGSSEFDQLKKIFEVIGLPPAGDWPEG 896

Query: 274 INMKARNYLQSLPSKTKVAWAKLFPKSDSKALDLLDRMLTFNPNKRITVEEALAHPYLEQ 333
           +++  RN  +  P    V    L P+ D +A DL+++ML F   +RI+  E+L HPYL  
Sbjct: 897 VSVH-RNSFRPTPP---VPLQTLVPEMDPQAKDLMEKMLVFKSGRRISSRESLLHPYLRD 1064

Query: 334 YYD 336
             D
Sbjct: 1065DLD 1073
>01060
          Length = 1800

 Score =  164 bits (416), Expect = 4e-41,   Method: Compositional matrix adjust.
 Identities = 104/310 (33%), Positives = 164/310 (52%), Gaps = 9/310 (2%)
 Frame = +1

Query: 44  TQLQYIGEGAYGMVSSAYDHVRKTRVAIKKISPFEHQTYC-QRTLREIQILLRFRHENVI 102
           T  Q IGEG YG+V          ++A+KKI     +       +REI +L   RH N++
Sbjct: 82  TDFQKIGEGTYGVVYKCRHRATGRKLAMKKIRLRGSEDGVPSSAIREIAMLRELRHTNIV 261

Query: 103 GIRDILRAPTLEAMRDVYIVQDLMETDLY----KLLKSQQLSNDHICYFLYQILRGLKYI 158
            + D++    +E  R +++V + +  DL     K  +   L    +  +++QI+ G+ + 
Sbjct: 262 CLEDVI----MEDER-LFLVFEFLSMDLKMYIDKFPEGVVLDRRLVKSYVFQIVTGIXFC 426

Query: 159 HSANVLHRDLKPSNLLINTTCDLKICDFGLAR-IADPEHDHTGFLTEYVATRWYRAPEIM 217
           H   ++HRDLKP NLLIN T  +KI DFG+AR  A P   +T      V T WYRAPEI+
Sbjct: 427 HQRRIVHRDLKPQNLLINHTGAIKIADFGMARTFALPVRAYT----HEVVTLWYRAPEIL 594

Query: 218 LNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINMK 277
           + +  Y+  +D+WS+G I A+ML   PIF G   +DQL  I  I+G+P+++       + 
Sbjct: 595 MGASKYSTPVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIFRIIGTPTEQTWPEFHKLP 774

Query: 278 ARNYLQSLPSKTKVAWAKLFPKSDSKALDLLDRMLTFNPNKRITVEEALAHPY---LEQY 334
           A N +  L  + K+  ++     DS  LDL++R L  +P +RI+ ++ L H Y   ++  
Sbjct: 775 AFNGMFPLWKEGKL--SETLTDLDSLGLDLIERTLKCDPAQRISCKKMLQHAYFLNVDTS 948

Query: 335 YDPTDEPVAE 344
             P D P  E
Sbjct: 949 VKPVDVPSPE 978
>29581
          Length = 1278

 Score =  153 bits (386), Expect = 1e-37,   Method: Compositional matrix adjust.
 Identities = 91/278 (32%), Positives = 149/278 (53%), Gaps = 4/278 (1%)
 Frame = -2

Query: 92   ILLRFRHENVIGIRDILRAPTLEAMRDVYIVQDLMETDLYKLLKSQQ--LSNDHICYFLY 149
             LL  RH+N++ +++++   +L+++   ++V +  E DL  LL +     S   +   + 
Sbjct: 1196 FLLNLRHQNIVQLQEVVVGKSLDSL---FLVMEYCEQDLASLLDNMPAPFSESQVKCIVL 1026

Query: 150  QILRGLKYIHSANVLHRDLKPSNLLINTTCDLKICDFGLAR-IADPEHDHTGFLTEYVAT 208
            Q+L+GL+Y+H A ++HRDLK SNLL+     +KI DFGLAR    P+      +T  V T
Sbjct: 1025 QLLKGLRYLHEAFIIHRDLKVSNLLMTDKGCVKIADFGLARNYGKPQKP----MTPKVVT 858

Query: 209  RWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQE 268
             WYRAPE++  SK ++ +ID+WS GCIL E+L ++P+ PG+  L Q+  I+ +LG+P+  
Sbjct: 857  LWYRAPELLFGSKTHSTAIDMWSAGCILGELLGHKPLMPGRSDLQQIELIMELLGTPNDT 678

Query: 269  DLNCIINMKARNYLQSLPSKTKVAWAKLFPKSDSKALDLLDRMLTFNPNKRITVEEALAH 328
                   + A     +L  +        FP      + LL+ +  ++P KR T E+ L H
Sbjct: 677  IWPGFSQLPAFEQF-TLKKQPYNNLRHTFPWLSESGIRLLNGLFMYHPQKRATAEDCLEH 501

Query: 329  PYLEQYYDPTDEPVAEEPFTFDME-LDDLPKERLKELI 365
             Y +           E+P+  D E +   P+ RLK  I
Sbjct: 500  SYFK-----------EQPYPCDPEFMPSFPQHRLKRRI 420
>01756
          Length = 1858

 Score =  148 bits (373), Expect = 4e-36,   Method: Compositional matrix adjust.
 Identities = 113/317 (35%), Positives = 163/317 (51%), Gaps = 9/317 (2%)
 Frame = -3

Query: 36   PF-DVGPRYTQLQYIGEGAYGMVSSAYDHVRKTRVAIKKI-SPFEHQTYCQRTLREIQIL 93
            PF D   +Y +L  IG+G +G V  A     K  VA+KK+    E + +    LREI+IL
Sbjct: 1760 PFCDEDAKYEKLAKIGQGTFGEVFKARCKKTKQVVAMKKVLMDNEKEGFPITALREIKIL 1581

Query: 94   LRFRHENVIGIRDILRAPTLEAMR---DVYIVQDLMETDLYKLLKSQQLSND--HICYFL 148
                HENV+ + +I       A R     Y+V +  E DL  LL +  +  +   I   +
Sbjct: 1580 QLLNHENVVDLIEICSTKATSANRYKSMFYLVFEFCEHDLAGLLSNMSVVFNLPEIKEVM 1401

Query: 149  YQILRGLKYIHSANVLHRDLKPSNLLINTTCDLKICDFGLARIADPEHDHTGFLTEYVAT 208
             Q++ GL YIH   +LHRD+K +N+LI     LK+ DFGLAR            T  V T
Sbjct: 1400 KQLMNGLYYIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRVVT 1221

Query: 209  RWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQE 268
             WYR PE++L  + Y+ +ID W  GCI+AEM +  PI  G    +QL  I  + GS + E
Sbjct: 1220 LWYRPPELLLGDRNYSTAIDQWGAGCIMAEMWTRNPIMQGTTEQNQLTLITQLCGSITPE 1041

Query: 269  DLNCIINMKARNYLQSLP--SKTKVAWAKLFPKSDSKALDLLDRMLTFNPNKRITVEEAL 326
                +  ++  N L  LP  +K KV     +   D+ ALDLLD++L  +P KR+  +EAL
Sbjct: 1040 VWPGVERLELYNSL-DLPQGNKRKVKERLRYYIKDAYALDLLDKLLALDPGKRVNSDEAL 864

Query: 327  AHPYLEQYYDPTDEPVA 343
            +H +   + DP   P+ 
Sbjct: 863  SHDFF--WMDPEPLPLT 819
>01707
          Length = 757

 Score =  140 bits (354), Expect = 7e-34,   Method: Compositional matrix adjust.
 Identities = 77/224 (34%), Positives = 125/224 (55%), Gaps = 2/224 (0%)
 Frame = +1

Query: 42  RYTQLQYIGEGAYGMVSSAYDHVRKTRVAIKKISPFEHQTYCQR-TLREIQILLRFRHEN 100
           +Y ++  IGEG+YG+V    +      VAIKK    E     ++  +REI++L + +H N
Sbjct: 67  KYEKIGKIGEGSYGVVFKCRNKETSQLVAIKKFVESEDDPLIKKIAMREIRMLKQLKHPN 246

Query: 101 VIGIRDILRAPTLEAMRDVYIVQDLM-ETDLYKLLKSQQLSNDHICYFLYQILRGLKYIH 159
           ++ + ++ R      +   Y+   L+ E D Y     + L    +   +YQ L  + + H
Sbjct: 247 LVRLIEVFRRKKRLHLVFDYVDHTLLNELDRY----PRGLPEPMVKRIIYQTLLAVNFCH 414

Query: 160 SANVLHRDLKPSNLLINTTCDLKICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLN 219
             N +HRD+KP N+LI     +K+CDFG ARI     D     T+YVATRWYRAPE+++ 
Sbjct: 415 QYNTIHRDVKPENILITRQGQVKLCDFGFARILTGPGDE---YTDYVATRWYRAPELLVG 585

Query: 220 SKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILG 263
              Y   +D+W++GC+ AE+L+ + ++PG+  +DQL+ I   LG
Sbjct: 586 DTQYGPPVDVWAIGCVFAELLTGQALWPGRSDVDQLHLIRKTLG 717
>04591
          Length = 1117

 Score =  131 bits (330), Expect = 4e-31,   Method: Compositional matrix adjust.
 Identities = 86/264 (32%), Positives = 135/264 (51%), Gaps = 8/264 (3%)
 Frame = -2

Query: 86   TLREIQILLRFRHENVIGIRDILR---APTLEAMRDVYIVQDLMETDLYKLLKSQQL--S 140
             LREI+IL +  HENV+ +++I      P        Y++ +  + DL  LL + ++  S
Sbjct: 1080 ALREIKILQQLEHENVVQLQEICHTQAGPYNRYKSTFYLIFEYCDYDLAGLLNNLRVKFS 901

Query: 141  NDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLINTTCDLKICDFGLARIADPEHDHTG 200
                   + Q+L GL YIH+  +LHRD+K +N+L+     LK+ DFGL+R        + 
Sbjct: 900  LADKKNLMSQLLNGLFYIHTKQILHRDIKAANILLTRDGVLKLADFGLSR----PWVKSK 733

Query: 201  FLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILG 260
             LT  V T WYR PE++L  + Y   ID+W VGCI+AEM S +P+  G+    QL+ I  
Sbjct: 732  RLTNRVVTLWYRPPELLLGEREYGPEIDMWGVGCIMAEMWSRKPLMQGRSEQHQLSLITD 553

Query: 261  ILGSPSQEDLNCIINMKARNYL---QSLPSKTKVAWAKLFPKSDSKALDLLDRMLTFNPN 317
            + GS + E    +  ++    L   Q  P K K     L    + +  +L+D  L  +P 
Sbjct: 552  LCGSLNAEVWPGVTKLELYGKLDLPQGKPRKVKERMLDLL--KNKEGAELIDIFLRLDPG 379

Query: 318  KRITVEEALAHPYLEQYYDPTDEP 341
            +R+  + AL+H +   + DP   P
Sbjct: 378  QRMNCDNALSHDFF--WVDPLPSP 313
>04138
          Length = 800

 Score =  115 bits (287), Expect = 4e-26,   Method: Compositional matrix adjust.
 Identities = 76/224 (33%), Positives = 108/224 (48%), Gaps = 3/224 (1%)
 Frame = +1

Query: 155 LKYIHSANVLHRDLKPSNLLINTTCDLKICDFGLARIADPEHDHTGFLTEYVATRWYRAP 214
           L YIH   +LHRD+K +N+LI     LK+ DFGLAR            T  V T WYR P
Sbjct: 52  LYYIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRVVTLWYRPP 231

Query: 215 EIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCII 274
           E++L  + Y+ +ID W  GCI+AEM +  PI  G    +QL  I  + GS + E    + 
Sbjct: 232 ELLLGDRNYSTAIDQWGAGCIMAEMWTRNPIMQGTTEQNQLTLITQLCGSITPEVWPGVT 411

Query: 275 NMKARNYLQ-SLPSKTKVAWAKLFPK--SDSKALDLLDRMLTFNPNKRITVEEALAHPYL 331
            +   + ++ +L +  K      F +   D   LDL +R+L  +P++RI+ +EAL H + 
Sbjct: 412 QLSMYHQIKGALAAGRKNIIRDRFARILKDPYGLDLFERLLKMDPSQRISADEALNHDFF 591

Query: 332 EQYYDPTDEPVAEEPFTFDMELDDLPKERLKELIFQETARFQPG 375
                     V  EP +    L      RLK   FQ T    PG
Sbjct: 592 W---------VGVEPKSLVGVL-----SRLKMSSFQYTQSGFPG 681
>32000
          Length = 644

 Score =  114 bits (286), Expect = 5e-26,   Method: Compositional matrix adjust.
 Identities = 65/162 (40%), Positives = 91/162 (56%), Gaps = 7/162 (4%)
 Frame = -1

Query: 178 TCDLKICDFGLARIAD-PEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCIL 236
           T  +KI DFGLAR+   P   +T      V T WYRAPEI+L  + Y+  +DIWS+GCI 
Sbjct: 581 TAKMKIADFGLARVFGLPVRTYT----HEVITLWYRAPEILLGCRFYSVPVDIWSLGCIF 414

Query: 237 AEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINMKARNYLQSLPS------KTK 290
            EM++ R +FPG   +DQL  I   LG+P ++    +   K  +Y  + P       +T 
Sbjct: 413 VEMMTRRALFPGDSEIDQLYRIFRTLGTPDEKVWPGV--SKLPDYKPTFPKWPLKNLETV 240

Query: 291 VAWAKLFPKSDSKALDLLDRMLTFNPNKRITVEEALAHPYLE 332
           V+ +K+        LDLL RMLT+NPN+RI+   A+ HPY  
Sbjct: 239 VSLSKV-------GLDLLKRMLTYNPNRRISARSAMRHPYFN 135
>31489
          Length = 329

 Score =  104 bits (259), Expect = 7e-23,   Method: Compositional matrix adjust.
 Identities = 52/87 (59%), Positives = 71/87 (81%), Gaps = 2/87 (2%)
 Frame = +3

Query: 90  IQILLRFRHENVIGIRDILR-APTLEAMRDVYIVQDLMETDLYKLLKSQQ-LSNDHICYF 147
           I+IL  F+H+N+I IR+IL+   +    +D+++V DLME+DL++++ S Q L+ +HI YF
Sbjct: 3   IKILKHFKHDNIISIREILKPKDSYHDFKDIHVVFDLMESDLHRIIYSDQPLTEEHIRYF 182

Query: 148 LYQILRGLKYIHSANVLHRDLKPSNLL 174
           LYQILRGLKYIHSANV+HRDLKPSNLL
Sbjct: 183 LYQILRGLKYIHSANVVHRDLKPSNLL 263
>18287
          Length = 678

 Score = 90.1 bits (222), Expect = 1e-18,   Method: Compositional matrix adjust.
 Identities = 48/113 (42%), Positives = 71/113 (62%), Gaps = 2/113 (1%)
 Frame = -3

Query: 223 YTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINMKARNYL 282
           Y  SIDIWSVGCI AE+LS R +F  +  + QL+ I+ ++G+P  ED+       ARN++
Sbjct: 673 YDYSIDIWSVGCIFAELLSRRILFQAQGPVQQLDMIINLVGTPRPEDMERACE-GARNHI 497

Query: 283 QSLPSKTK--VAWAKLFPKSDSKALDLLDRMLTFNPNKRITVEEALAHPYLEQ 333
            + P + +  +    L P +  +A+ LL RML  NP  RI+ EEAL+HPYL++
Sbjct: 496 LNQPFRRQNLLTLYNLSPHATHEAVRLLTRMLILNPKNRISAEEALSHPYLDE 338
>28638
          Length = 1458

 Score = 58.9 bits (141), Expect(3) = 1e-17,   Method: Compositional matrix adjust.
 Identities = 36/105 (34%), Positives = 59/105 (56%), Gaps = 7/105 (6%)
 Frame = -1

Query: 147 FLYQILRGLKYIHS--ANVLHRDLKPSNLLINTTCD-----LKICDFGLARIADPEHDHT 199
           F  Q+   L ++ +   N++H DLKP N+L+   C+     +KI DFG +          
Sbjct: 822 FAQQLCTALLFLATPEMNIIHCDLKPENILL---CNPKRSAIKIVDFGSSCQLGQR---- 664

Query: 200 GFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRP 244
             + +Y+ +R+YR+PE++L    Y  +ID+WS+GCIL EM +  P
Sbjct: 663 --IYQYIQSRFYRSPEVLLGVP-YDLAIDMWSLGCILVEMHTGEP 538

 Score = 35.8 bits (81), Expect(3) = 1e-17,   Method: Compositional matrix adjust.
 Identities = 30/98 (30%), Positives = 51/98 (52%), Gaps = 3/98 (3%)
 Frame = -3

Query: 42   RYTQLQYIGEGAYGMVSSAYDHVRKTRVAIKKI---SPFEHQTYCQRTLREIQILLRFRH 98
            RY     IG+G++G V  AYDH  + +VAIK I    PF +Q   Q  ++ ++++ R   
Sbjct: 1144 RYEIDSLIGKGSFGQVVKAYDHGDQEQVAIKIIKNKKPFLNQ--AQIEVKLLELMNRHDA 971

Query: 99   ENVIGIRDILRAPTLEAMRDVYIVQDLMETDLYKLLKS 136
            +N   I  + R         + +V +L+  +LY LL++
Sbjct: 970  DNXYYIVRLKRHFMFR--NHLCLVFELLSYNLYDLLRN 863

 Score = 32.3 bits (72), Expect(3) = 1e-17,   Method: Compositional matrix adjust.
 Identities = 33/127 (25%), Positives = 47/127 (37%), Gaps = 34/127 (26%)
 Frame = -2

Query: 244 PIFPGKHYLDQLNHILGILGSPSQEDLNCIINMKARNYLQSLPSKT----KVAWAKLFPK 299
           P+F G +  DQ+  I+ +LG P +  L+     K R Y   LP  T    K    K +  
Sbjct: 539 PLFAGSNEFDQMMKIVEVLGVPPRHILD--QAQKTRKYFDLLPDGTYAPKKPRDNKKYKS 366

Query: 300 SDSKAL------------------------------DLLDRMLTFNPNKRITVEEALAHP 329
             S+ L                              DL+ RML F+P  RI+   AL H 
Sbjct: 365 PSSRKLHEVLGAEKGGPGGRRMGEPGHTVADYLKFKDLILRMLDFDPKTRISPYYALQHN 186

Query: 330 YLEQYYD 336
           +  +  D
Sbjct: 185 FFRKTSD 165
>13592
          Length = 980

 Score = 86.7 bits (213), Expect = 2e-17,   Method: Compositional matrix adjust.
 Identities = 61/202 (30%), Positives = 106/202 (52%), Gaps = 7/202 (3%)
 Frame = +2

Query: 49  IGEGAYGMVSSAYDHVRKTRVAIKKISPFEHQTYCQRTL-REIQILLRFRHENVIGIRDI 107
           IG+G +G V +A ++     +A+K+I+    +T   + +  E++IL   +H+N++     
Sbjct: 8   IGQGRFGKVYTAVNNNTGELMAMKEIAIQPGETRALKNVAEELKILEGIKHKNLV----- 172

Query: 108 LRAPTLEAMRDVYIV--QDLMETDLYKLLK-SQQLSNDHICYFLYQILRGLKYIHSANVL 164
            R   +E  R+  ++  +   E  L  L++ +  L       F  Q+L G+  +H   ++
Sbjct: 173 -RYYGIEVHREELLIFMELCSEGTLESLVELTGGLPEALSRRFTAQLLSGVAELHKHGIV 349

Query: 165 HRDLKPSNL-LINTTCDLKICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIML--NSK 221
           HRD+K +N+ L++ +  LK+ DFG A          G L  YV T+ Y APE+    NS 
Sbjct: 350 HRDIKTANIFLVDGSNSLKLGDFGSAVKIQAHTTVPGELQGYVGTQAYMAPEVFTKTNSD 529

Query: 222 GYTKSIDIWSVGCILAEMLSNR 243
           G+ +  DIWSVGC++ EM S +
Sbjct: 530 GHGRLADIWSVGCVVVEMASGK 595
>01966
          Length = 1735

 Score = 85.5 bits (210), Expect(2) = 3e-17,   Method: Compositional matrix adjust.
 Identities = 53/155 (34%), Positives = 84/155 (54%), Gaps = 5/155 (3%)
 Frame = -1

Query: 86   TLREIQILLRFRHENVIGIRDILRAPTLEAMRDVYIVQDLMETDLY----KLLKSQQLSN 141
             +REI +L   RH N++ + D++    +E  R +++V + +  DL     K  +   L  
Sbjct: 1573 AIREIAMLRELRHTNIVCLEDVI----MEDER-LFLVFEFLSMDLKMYIDKFPEGVVLDR 1409

Query: 142  DHICYFLYQILRGLKYIHSANVLHRDLKPSNLLINTTCDLKICDFGLAR-IADPEHDHTG 200
              +  +++QI+ G+ + H   ++HRDLKP NLLIN T  +KI DFG+AR  A P   +  
Sbjct: 1408 RLVKSYVFQIVTGINFCHQRRIVHRDLKPQNLLINHTGAIKIADFGMARTFALPVRAY-- 1235

Query: 201  FLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCI 235
              T  V T WYRAPEI++   G   +   W+ G +
Sbjct: 1234 --THEVVTLWYRAPEILM---GPQSTPPXWTCGAL 1145

 Score = 20.4 bits (41), Expect(2) = 3e-17,   Method: Compositional matrix adjust.
 Identities = 8/13 (61%), Positives = 10/13 (76%)
 Frame = -2

Query: 45   QLQYIGEGAYGMV 57
            +L  IGEG YG+V
Sbjct: 1698 RLSKIGEGTYGVV 1660

 Score = 72.0 bits (175), Expect = 4e-13,   Method: Compositional matrix adjust.
 Identities = 41/130 (31%), Positives = 69/130 (53%), Gaps = 3/130 (2%)
 Frame = -3

Query: 219  NSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINMKA 278
             +  Y+  +D+WS+G I A+ML   PIF G   +DQL  I  I+G+P+++       + A
Sbjct: 1187 GASKYSTPVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIFRIIGTPTEQTWPEFHKLPA 1008

Query: 279  RNYLQSLPSKTKVAWAKLFPKSDSKALDLLDRMLTFNPNKRITVEEALAHPY---LEQYY 335
             N +  L  + K+  ++     DS  LDL++R L  +P +RI+ ++ L H Y   ++   
Sbjct: 1007 FNGMFPLWKEGKL--SETLTDLDSLGLDLIERTLKCDPAQRISCKKMLQHAYFLNVDTSV 834

Query: 336  DPTDEPVAEE 345
             P D P  E+
Sbjct: 833  KPVDVPSPEQ 804
>03508
          Length = 1463

 Score = 84.3 bits (207), Expect = 8e-17,   Method: Compositional matrix adjust.
 Identities = 46/150 (30%), Positives = 88/150 (58%), Gaps = 2/150 (1%)
 Frame = +1

Query: 100 NVIGIRDILRAPTLEAMRDVYIVQDLMETDLYKLLKSQQLSNDHICYFLYQILRGLKYIH 159
           NVI +  I++ P   +     I + +  TD  +L   Q  ++  I ++LY++++ L + H
Sbjct: 757 NVITLLAIVKDPV--SRTPALIFEHVNNTDFKQLY--QTFTDYDIRFYLYELMKALDFCH 924

Query: 160 SANVLHRDLKPSNLLIN-TTCDLKICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIML 218
           S  ++HRD+KP N++I+     L++ D+GLA    P  ++       VA+R+++ PE++L
Sbjct: 925 SMGIMHRDVKPHNVMIDHENKKLRLIDWGLAEFYHPGMEYN----VRVASRYFKGPELLL 1092

Query: 219 NSKGYTKSIDIWSVGCILAEMLSNR-PIFP 247
           + + Y  S+D+WS+GC+ A M+  + P+ P
Sbjct: 1093DYQMYDYSLDMWSLGCMFASMIFRKEPLLP 1182

 Score = 44.7 bits (104), Expect = 7e-05,   Method: Compositional matrix adjust.
 Identities = 38/137 (27%), Positives = 60/137 (43%), Gaps = 15/137 (10%)
 Frame = +2

Query: 210  WYRAPEIMLNSKGYTKSIDI-WSVG----CILAEMLSNRPIFPGKHYLDQLNHILGILGS 264
            W RA     N    T+ +   W+ G    C+ A      P F G    DQL  I  +LG+
Sbjct: 1055 WRRATSRDQNYCWTTRCMTTHWTCGVWAACLPA*SSGKSPFFHGHDNYDQLVRIAKVLGT 1234

Query: 265  PSQEDLNCII-----NMKARNYLQSLPSKTKVAWAKLFPKSDS-----KALDLLDRMLTF 314
               +DL   I     ++  R +   L   ++  W +     +      +ALD LD++L +
Sbjct: 1235 ---DDLYGYIEKYQIDLDPR-FNDILGRHSRKRWERFVHSENQHLISPEALDFLDKLLRY 1402

Query: 315  NPNKRITVEEALAHPYL 331
            + N+R+T  EA+ HPY 
Sbjct: 1403 DHNERLTAREAMDHPYF 1453
>23319
          Length = 2235

 Score = 84.0 bits (206), Expect = 1e-16,   Method: Compositional matrix adjust.
 Identities = 43/113 (38%), Positives = 64/113 (56%), Gaps = 1/113 (0%)
 Frame = +3

Query: 220 SKGYTKSIDIWSVGCILAEML-SNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINMKA 278
           +K Y+ SID+WS GCI AE+  + RP+FPG    DQL  I  +LG+P+++    +  +  
Sbjct: 18  AKMYSTSIDMWSAGCIFAELANAGRPLFPGNDDDDQLKRIFKLLGTPTEDQWPGMTQLP- 194

Query: 279 RNYLQSLPSKTKVAWAKLFPKSDSKALDLLDRMLTFNPNKRITVEEALAHPYL 331
            NY           W ++ PK +SK  DLL  +L   P+ R++ +EAL HPY 
Sbjct: 195 -NYRMFPMYHVTTTWQQVVPKLNSKGRDLLQCLLVCCPSDRMSADEALQHPYF 350
>15910
          Length = 1361

 Score = 82.4 bits (202), Expect = 2e-16,   Method: Compositional matrix adjust.
 Identities = 58/185 (31%), Positives = 89/185 (48%), Gaps = 3/185 (1%)
 Frame = +2

Query: 151 ILRGLKYIHSANVLHRDLKPSNLLINTTCD---LKICDFGLARIADPEHDHTGFLTEYVA 207
           IL G++YIH+  V+HRDLKP NLL     D   LK+ DFGL+RI +PE      ++    
Sbjct: 491 ILHGVQYIHANGVVHRDLKPENLLYECMTDDSKLKLADFGLSRIIEPEVQ----MSTVCG 658

Query: 208 TRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQ 267
           T  Y APE++   K YT S+D+WSVG I   +L     F  ++  +    I+       +
Sbjct: 659 TPGYCAPEVLKGDK-YTPSVDMWSVGVIAYILLCGYEPFFAENEFEMYRKIIKGEYKFDE 835

Query: 268 EDLNCIINMKARNYLQSLPSKTKVAWAKLFPKSDSKALDLLDRMLTFNPNKRITVEEALA 327
           E                        W+++       A D++ ++L  +P KR+T  EAL 
Sbjct: 836 E-----------------------YWSEI----SENAKDVVRKLLVIDPKKRLTATEALR 934

Query: 328 HPYLE 332
            P+++
Sbjct: 935 LPWVK 949
>18921
          Length = 697

 Score = 76.3 bits (186), Expect = 2e-14,   Method: Compositional matrix adjust.
 Identities = 59/203 (29%), Positives = 97/203 (47%), Gaps = 4/203 (1%)
 Frame = +2

Query: 46  LQYIGEGAYGMVSSAYDHVRKTRVAIKKISPFEHQTYCQRTLREIQILLRFRHENVIGIR 105
           L  +GEG+YG V  +        +AIK++ P +  T  Q  ++EI I+ +   + ++   
Sbjct: 44  LGKLGEGSYGSVFKSLHKETGQVLAIKQV-PVD--TDLQEIIKEISIMQQCDSKYIVKYY 214

Query: 106 DILRAPTLEAMRDVYIVQDLME----TDLYKLLKSQQLSNDHICYFLYQILRGLKYIHSA 161
                 T     D++IV +       +D+ +L +++ L    I   LY  L+GL Y+HS 
Sbjct: 215 GSYFKNT-----DLWIVMEYCGAGSVSDIMRL-RNKTLVEREIATILYYTLKGLXYLHSR 376

Query: 162 NVLHRDLKPSNLLINTTCDLKICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLNSK 221
             +HRD+K  N+L+N     K+ DFG   +A    D        + T ++ APE+ +   
Sbjct: 377 RKIHRDIKAGNILLNNEGHAKLADFG---VAGQLTDTMAKRNTVIGTPYWMAPEV-IQEI 544

Query: 222 GYTKSIDIWSVGCILAEMLSNRP 244
           GY    DIWS+G    EM   +P
Sbjct: 545 GYDCVADIWSLGITALEMAEGKP 613
>00300
          Length = 2318

 Score = 75.5 bits (184), Expect = 3e-14,   Method: Compositional matrix adjust.
 Identities = 60/236 (25%), Positives = 112/236 (47%), Gaps = 8/236 (3%)
 Frame = -1

Query: 42   RYTQLQYIGEGAYGMVSSAYDHVRKTRVAIK--KISPFEHQTYCQRTLREIQILLRFRHE 99
            R+ +   IGEG +G V +A +      +A+K  K  P + Q   +    EI+I    +HE
Sbjct: 1655 RWQRGNKIGEGQFGKVYTAVNMSTGELMALKEMKFQPNDLQQ-LREMCDEIKIFEGIQHE 1479

Query: 100  NVIGIRDILRAPTLEAMRD-VYIVQDLMETDLYKLLKSQQLSNDHICYFLYQILRGLKYI 158
            N++      +   +E  +D + +  +  +T   +      L    I  +  +I+  + ++
Sbjct: 1478 NLV------KYYGVEVHKDEMLMFMEYCDTGTIEEAAKMGLPEYLIRRYTREIVLAVNHL 1317

Query: 159  HSANVLHRDLKPSNLLINTTCDLKICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIML 218
            H  +++HRD+K +N+ + +   +K+ DFG +          G     V T  Y APE+  
Sbjct: 1316 HENSIVHRDIKGANIFLTSNGHVKLGDFGCSVKLKSHTTMPGEFHNLVGTTAYMAPEVFT 1137

Query: 219  --NSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLD---QLNHILGILGSPSQED 269
              +  GY ++ DIWS+GC++ EM + +  +   H LD   Q+ + +GI   P+  D
Sbjct: 1136 QNDQGGYGRAADIWSLGCVVIEMATGKRPW---HDLDNNYQIMYKVGIGHKPAVPD 978
>01392
          Length = 1806

 Score = 75.1 bits (183), Expect = 5e-14,   Method: Compositional matrix adjust.
 Identities = 59/191 (30%), Positives = 86/191 (45%), Gaps = 9/191 (4%)
 Frame = -1

Query: 150  QILRGLKYIHSANVLHRDLKPSNLL---INTTCDLKICDFGLAR--IADPEHDHTGFLTE 204
             I R L ++HS  + HRDLKP N+L   ++    +KICDF LA     D +   T  L  
Sbjct: 1767 HIARALDFLHSKGIAHRDLKPENILCEHLDDVVPVKICDFDLASGISCDGDGTKTPELLT 1588

Query: 205  YVATRWYRAPEI----MLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILG 260
             V +  Y APE+    + +S  Y K  D+WS+G IL  ML   P F G     Q     G
Sbjct: 1587 PVGSAEYMAPEVVDAWVGDSFSYDKRCDLWSLGIILYIMLCGYPPFYG-----QCGEDCG 1423

Query: 261  ILGSPSQEDLNCIINMKARNYLQSLPSKTKVAWAKLFPKSDSKALDLLDRMLTFNPNKRI 320
                 +  D   ++    ++     PS+    W  +     S A DL+  +L   P KR 
Sbjct: 1422 WNRGEACHDCQDMLFNSIQDGHYKFPSQE---WTSI----SSSAKDLIRHLLVREPRKRY 1264

Query: 321  TVEEALAHPYL 331
            +  + L HP++
Sbjct: 1263 SAADVLKHPWI 1231
>09606
          Length = 1300

 Score = 71.6 bits (174), Expect = 5e-13,   Method: Compositional matrix adjust.
 Identities = 71/307 (23%), Positives = 122/307 (39%), Gaps = 23/307 (7%)
 Frame = -3

Query: 49   IGEGAYGMVSSAYDHVRKTRVAIKKISPFEHQTYCQR--TLREIQILLRFRHENVIGIRD 106
            +G+G + ++   Y   RK  +    I   E    C+R      +++     H NV+   +
Sbjct: 1091 LGKGEHSII---YKGRRKGTINFVAIHCIEK---CKRPEVTNTVRMTHDISHPNVVQFHE 930

Query: 107  ILRAPTLEAMRDVYIVQDLMETDLYK--LLKSQQLSNDHICYFLYQILRGLKYIHSANVL 164
                   E    +++V +L         L +   L    I  F   ++ GL YIHS  +L
Sbjct: 929  WY-----ETSNHLWLVVELCTGGSLADILAQDHHLPETSIRDFGIHLVTGLHYIHSLGIL 765

Query: 165  HRDLKPSNLLINTTCDLKICDFGLARIADPEHDHTGFLTEYVATRW-------------- 210
              DL+PS +L++T+  LK  DFGL+++     +   F       +W              
Sbjct: 764  FHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEAGDQWNIQSAEEMMKQVPT 585

Query: 211  -----YRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSP 265
                 Y APE+   ++    S D+W++GC+  EM S  P F G+ Y              
Sbjct: 584  SGSPTYMAPEVFQGAEPSIMS-DLWALGCVFYEMFSGHPPFLGETY-------------- 450

Query: 266  SQEDLNCIINMKARNYLQSLPSKTKVAWAKLFPKSDSKALDLLDRMLTFNPNKRITVEEA 325
                   I   K  N    LP   KV  ++L  K   + L+LL+ +L  +  +R++    
Sbjct: 449  ------DITKDKVLNKEFPLP---KVKGSRLSAKPSPEFLNLLESLLQKDSTRRLSWASL 297

Query: 326  LAHPYLE 332
            + H + +
Sbjct: 296  VKHAFWQ 276
>12721
          Length = 821

 Score = 71.2 bits (173), Expect = 7e-13,   Method: Compositional matrix adjust.
 Identities = 48/199 (24%), Positives = 98/199 (49%), Gaps = 1/199 (0%)
 Frame = +1

Query: 49  IGEGAYGMVSSAYDHVRKTRVAIKKISPFEHQTYCQRTLREIQILLRFRHENVIGIRDIL 108
           IGEG+ G+V  A     + ++A+KK+     Q   +    E+ ++  + H N++ + +  
Sbjct: 112 IGEGSTGIVCIATSRDGR-QMAVKKMD-LRKQQRRELLFNEVVVMRDYHHPNIVEMYN-- 279

Query: 109 RAPTLEAMRDVYIVQDLMETD-LYKLLKSQQLSNDHICYFLYQILRGLKYIHSANVLHRD 167
              +     ++++V + ME   L  ++ + ++    I       L+ L ++H+  V+HRD
Sbjct: 280 ---SYLVNDELWVVMEFMEGGALTDIVTNNRMDEVQIATVCRACLKALAFLHANGVIHRD 450

Query: 168 LKPSNLLINTTCDLKICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSI 227
           +K  ++L++    +K+ DFG       +      L   V T ++ APE+ ++   Y   +
Sbjct: 451 IKSDSILLSHDGKVKLXDFGFCAQVTQDLQKRKSL---VGTPYWMAPEV-ISRLPYGPEV 618

Query: 228 DIWSVGCILAEMLSNRPIF 246
           DIWS+G ++ EM+   P F
Sbjct: 619 DIWSLGIMVMEMIDAEPPF 675
>13212
          Length = 1067

 Score = 70.5 bits (171), Expect = 1e-12,   Method: Compositional matrix adjust.
 Identities = 52/200 (26%), Positives = 87/200 (43%), Gaps = 5/200 (2%)
 Frame = -1

Query: 139 LSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLINTTCDLKICDFGL-ARIADPEHD 197
           ++   ICY  +++   L ++H  +V+HRD+K  N+L+    ++K+ DFG+ A+    +  
Sbjct: 989 MTEAQICYVCHEMCMALDFLHRHHVIHRDIKAGNVLLTIDGEVKLADFGVSAKNTQTQQK 810

Query: 198 HTGFLTEYVATRWYRAPEIM----LNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLD 253
              F    + T ++ APE++    L    Y    DIWS+G  L E     P  P K    
Sbjct: 809 RDTF----IGTPYWMAPEVVLCETLKDTPYDFKADIWSLGVTLIEFAQIEP--PNKEM-- 654

Query: 254 QLNHILGILGSPSQEDLNCIINMKARNYLQSLPSKTKVAWAKLFPKSDSKALDLLDRMLT 313
              H + +L    + D   +   K               W KLF        D + + L 
Sbjct: 653 ---HPMRVLIKIHKSDPPTLEKPK--------------KWTKLF-------KDFIAKCLV 546

Query: 314 FNPNKRITVEEALAHPYLEQ 333
            +PN R T  E L HP++++
Sbjct: 545 KDPNLRPTAAELLEHPFMKR 486
>06405
          Length = 1965

 Score = 70.5 bits (171), Expect = 1e-12,   Method: Compositional matrix adjust.
 Identities = 61/217 (28%), Positives = 100/217 (46%), Gaps = 6/217 (2%)
 Frame = +1

Query: 49  IGEGAYGMVSSAYDHVRKTRVAIKKISPFEHQTYCQRTLREIQILLRFRHENVIGIRDIL 108
           +G G YG V  A        VA+K +   E        L E  I+   +H N++ +  + 
Sbjct: 283 LGGGQYGDVYEAMWKRYNKIVAVKTLK--EDTMALNDFLEEAAIMKEMKHPNLVQLLGVC 456

Query: 109 -RAPTLEAMRDVYIVQDLM-ETDLYKLLKSQQLSNDHICYFLY---QILRGLKYIHSANV 163
            R P        YIV + M   +L   L+S     +     +Y   QI  G+ Y+ + N 
Sbjct: 457 TREPPF------YIVTEFMPHGNLLDYLRSSTREENGPTALMYMATQIASGMAYLETKNF 618

Query: 164 LHRDLKPSNLLINTTCDLKICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLNSKGY 223
           +HRDL   N L+  +  +K+ DFGLAR+   +  +T  +      +W  APE +  ++  
Sbjct: 619 IHRDLAARNCLVADSNMVKVADFGLARLMK-DDTYTAHIGAKFPIKWT-APEGLAFNRFS 792

Query: 224 TKSIDIWSVGCILAEMLS-NRPIFPGKHYLDQLNHIL 259
           T+S DIW+ G +L E+ +     +PG   L ++ H+L
Sbjct: 793 TRS-DIWAFGVLLWELATYGMSPYPGVE-LTEVYHLL 897
>18484
          Length = 635

 Score = 70.5 bits (171), Expect = 1e-12,   Method: Compositional matrix adjust.
 Identities = 38/122 (31%), Positives = 68/122 (55%), Gaps = 2/122 (1%)
 Frame = +1

Query: 130 LYKLLKSQQLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLINTTCDLKICDFGLA 189
           +Y++ +  +       ++  +I  GL ++H   +++RDLK  N+++++   +KI DFG+ 
Sbjct: 7   MYRIQQEGKFKEPVAAFYAAEIAVGLFFLHDQGIIYRDLKLDNVMLDSEGHIKIADFGMC 186

Query: 190 RIADPEHDHTGFLT--EYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFP 247
           +        TG  T   +  T  Y APEI+L    Y+KS+D W+ G +L EML+ +P F 
Sbjct: 187 K-----EGMTGDATTRTFCGTPDYIAPEIVLYQP-YSKSVDWWAYGVLLFEMLAGQPPFD 348

Query: 248 GK 249
           G+
Sbjct: 349 GE 354
>26560
          Length = 398

 Score = 70.1 bits (170), Expect = 1e-12,   Method: Compositional matrix adjust.
 Identities = 35/116 (30%), Positives = 63/116 (54%)
 Frame = -1

Query: 131 YKLLKSQQLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLINTTCDLKICDFGLAR 190
           Y L +    +   + ++  +++ GL+++HS  V++RDLKP+N+L++    ++I D GLA 
Sbjct: 389 YHLSQHGVFTEKEVRFYAAEVMLGLEHMHSRFVVYRDLKPANILLDENGHVRISDLGLAC 210

Query: 191 IADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIF 246
               +  H       V T  Y APE+++  + Y  S D +S GC+L ++L     F
Sbjct: 209 DFSKKRPHAS-----VGTHGYMAPEVLMKGQSYDSSADWFSFGCMLYKLLKGHSPF 57
>03294
          Length = 1684

 Score = 68.6 bits (166), Expect = 4e-12,   Method: Compositional matrix adjust.
 Identities = 40/121 (33%), Positives = 65/121 (53%), Gaps = 3/121 (2%)
 Frame = -1

Query: 227  IDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINMKARNYLQSLP 286
            +D+WS+G I A+ML   PIF G   +DQL  I  I+G+P+++       + A N +  L 
Sbjct: 1672 VDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIFRIIGTPTEQTWPEFHKLPAFNGMFPLW 1493

Query: 287  SKTKVAWAKLFPKSDSKALDLLDRMLTFNPNKRITVEEALAHPY---LEQYYDPTDEPVA 343
             + K+  ++     DS  LDL++R L  +P +RI+ ++ L H Y   ++    P D P  
Sbjct: 1492 KEGKL--SETLTDLDSLGLDLIERTLKCDPAQRISCKKMLQHAYFLNVDTSVKPVDVPSP 1319

Query: 344  E 344
            E
Sbjct: 1318 E 1316
>01718
          Length = 959

 Score = 67.4 bits (163), Expect = 8e-12,   Method: Compositional matrix adjust.
 Identities = 63/205 (30%), Positives = 97/205 (47%), Gaps = 6/205 (2%)
 Frame = +3

Query: 49  IGEGAYGMVSSAYDHVRKTRVAIKKISPFEHQTYCQRTLREIQILLRFRHENVIGIRDI- 107
           IG G +  V      +    +A+K  +   ++      LRE+Q+L R +H N++    + 
Sbjct: 171 IGAGFFSEVFKVTHRITGQVMALKMNTMTSNR---HNMLREVQLLNRLQHANILRFMGVC 341

Query: 108 LRAPTLEAMRDVYIVQDLMETDLYKLLKSQQLSNDHICYFLYQILRGLKYIHSANVLHRD 167
           +    L A+ + YI    +E  L K  K ++L           + RGL Y+HS   +HRD
Sbjct: 342 VHEGQLHALTE-YIPSGNLEQLLEK--KDEELPWTQRIQLTLGLARGLDYLHSTRFIHRD 512

Query: 168 LKPSNLLI----NTTCDLKICDFGLA-RIADPEHDHTGFLTEYVATRWYRAPEIMLNSKG 222
           L   N+LI    N      I DFGLA +I DP  D     T  V + ++ APE+ LN   
Sbjct: 513 LTSKNILIRREDNHGYHAVIADFGLATKIPDPL-DKEKLPT--VGSPYWMAPEV-LNGHF 680

Query: 223 YTKSIDIWSVGCILAEMLSNRPIFP 247
           Y +  D++SVG I+ E+ +  P  P
Sbjct: 681 YNERADLFSVGIIMCEITARIPADP 755
>03240
          Length = 1683

 Score = 67.4 bits (163), Expect = 9e-12,   Method: Compositional matrix adjust.
 Identities = 65/257 (25%), Positives = 106/257 (41%), Gaps = 53/257 (20%)
 Frame = -3

Query: 43   YTQLQYIGEGAYGMVSSAYDHVRKTRVAIKKISPFEHQTYCQRTLREIQILLRFRHENVI 102
            + +++ +G GA+G VS      RK    +          Y  +TLR+  +L R +  +V 
Sbjct: 1285 FEKIKTLGVGAFGEVSLC----RKNDTGM---------LYAMKTLRKSDVLKRNQVAHVK 1145

Query: 103  GIRDILRAPTLE-------AMRD---VYIVQDLM-ETDLYKLLKSQQLSNDHIC-YFLYQ 150
              RDIL     E       + +D   +Y V D +   DL  LL   ++ ++ +  +++ +
Sbjct: 1144 AERDILAEADNEWVVKLYYSFQDHNYLYFVMDYVPGGDLMGLLIRMEILDEPLARFYVAE 965

Query: 151  ILRGLKYIHSANVLHRDLKPSNLLINTTCDLKICDFGL---------------------- 188
            +++ ++ +H    +HRD+KP N+LI+    +K+ DFGL                      
Sbjct: 964  LVQAIESVHRMGFIHRDIKPDNILIDRNGHIKLTDFGLCTGFRWTHNSKYYQRDGTHARQ 785

Query: 189  --------------ARIADP-----EHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDI 229
                            I  P     + +        V T  Y APE++    GYT   D 
Sbjct: 784  DSMEVKCQLDEQCQCEILKPLERRRKREQRCLAHSLVGTPNYIAPEVLSRLGGYTSVCDW 605

Query: 230  WSVGCILAEMLSNRPIF 246
            WSVG IL EML   P F
Sbjct: 604  WSVGVILFEMLVGHPPF 554
>14420
          Length = 528

 Score = 67.0 bits (162), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 36/140 (25%), Positives = 69/140 (49%), Gaps = 1/140 (0%)
 Frame = +2

Query: 117 RDVYIVQDLMET-DLYKLLKSQQLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLI 175
            ++++V + +    L  ++    +    I     + L+ L+++H   V+HRD+K  N+L+
Sbjct: 119 EELWVVMEFLAGGSLTDVVTETCMDEGQIAAVCRECLQALEFLHENQVIHRDIKSDNILL 298

Query: 176 NTTCDLKICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCI 235
                +K+ DFG      PE      +   V T ++ APE+ +  K Y  ++DIWS+G +
Sbjct: 299 GMDGSVKLTDFGFCAQLSPEQSKRSTM---VGTPYWMAPEV-VTRKQYGPTVDIWSLGVM 466

Query: 236 LAEMLSNRPIFPGKHYLDQL 255
             EM+   P +  ++ L  L
Sbjct: 467 CIEMIEGEPPYLNENPLRAL 526
>19761
          Length = 473

 Score = 66.6 bits (161), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 37/102 (36%), Positives = 54/102 (52%), Gaps = 2/102 (1%)
 Frame = -3

Query: 144 ICYFLYQILRGLKYIHSAN--VLHRDLKPSNLLINTTCDLKICDFGLARIADPEHDHTGF 201
           I  +L Q    L Y+H+    +LHRDLKP N+ +    D+++ D GLAR      D   F
Sbjct: 417 IVCWLMQTASALNYMHTHTPVILHRDLKPQNIYVTEKGDVRLGDLGLARKLTGPAD---F 247

Query: 202 LTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNR 243
            T  V T  Y +PEI L+ + Y    DIWS+GC+  ++   +
Sbjct: 246 ATSQVGTIMYLSPEI-LSQQPYNSKSDIWSLGCVFYDITGKK 124
>21808
          Length = 1011

 Score = 65.9 bits (159), Expect = 3e-11,   Method: Compositional matrix adjust.
 Identities = 51/176 (28%), Positives = 85/176 (48%), Gaps = 4/176 (2%)
 Frame = +1

Query: 87  LREIQILLRFRHENVIGIRDILRAPTLEAMRDVYIVQDLMET-DLYKLL--KSQQLSNDH 143
           L E QI+ + RH  +I +  +           ++I+ +LM+   L + L  K + L    
Sbjct: 76  LAEAQIMKKLRHPKLIQLYAVCTQDD-----PIFIITELMKNGSLLEFLQGKGRVLKLPA 240

Query: 144 ICYFLYQILRGLKYIHSANVLHRDLKPSNLLINTTCDLKICDFGLARIADPEHDHTGFLT 203
           +     QI  G+ Y+ S N +HRDL   N+L++    +KI DFGLAR+   E ++   + 
Sbjct: 241 LIDIGAQIACGMAYLESQNYIHRDLAARNILVSDNNTVKIADFGLARVIK-EDEYEARVG 417

Query: 204 EYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLS-NRPIFPGKHYLDQLNHI 258
                +W  APE   N   +T   D+WS G +L E ++  R  +PG    + L+ +
Sbjct: 418 ARFPIKW-TAPEAA-NYNRFTIKSDVWSFGILLTETVTYGRVPYPGMTNAEVLHQV 579
>04852
          Length = 1462

 Score = 64.7 bits (156), Expect = 5e-11,   Method: Compositional matrix adjust.
 Identities = 34/95 (35%), Positives = 53/95 (55%)
 Frame = +1

Query: 147 FLYQILRGLKYIHSANVLHRDLKPSNLLINTTCDLKICDFGLARIADPEHDHTGFLTEYV 206
           + +QI RG++++ S   +HRDL   N+L+     LKI DFGL+R  D     +G     +
Sbjct: 340 YAFQIARGMEFLASRKCIHRDLAARNVLVTEEHVLKIADFGLSRTGDYYKKRSG---GRL 510

Query: 207 ATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLS 241
             +W  APE + + + YT   D+WS G +L E+ S
Sbjct: 511 PVKWM-APEALFDMR-YTTKSDVWSFGVVLWEIFS 609
>19094
          Length = 898

 Score = 64.7 bits (156), Expect = 6e-11,   Method: Compositional matrix adjust.
 Identities = 40/118 (33%), Positives = 58/118 (49%)
 Frame = +1

Query: 122 VQDLMETDLYKLLKSQQLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLINTTCDL 181
           V D+M       L+++ L    I   LY  L+GL Y+HS   +HRD+K  N+L+N     
Sbjct: 16  VSDIMR------LRNKTLVEREIATILYYTLKGL*YLHSRRKIHRDIKAGNILLNNEGHA 177

Query: 182 KICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEM 239
           K+ DFG   +A    D        + T ++ APE+ +   GY    DIWS+G    EM
Sbjct: 178 KLADFG---VAGQLTDTMAKRNTVIGTPYWMAPEV-IQEIGYDCVADIWSLGITALEM 339
>13066
          Length = 551

 Score = 64.3 bits (155), Expect = 8e-11,   Method: Compositional matrix adjust.
 Identities = 43/148 (29%), Positives = 69/148 (46%), Gaps = 2/148 (1%)
 Frame = +3

Query: 88  REIQILLRFRHENVIGIRDIL-RAPTLEAMRDVYIVQDLMETDLYKLLKSQQLSND-HIC 145
           RE+ +L +  H  +I I  IL R P     ++   ++     DL   ++      +    
Sbjct: 123 RELDLLTKLDHPYIIQIHSILQRXP-----KNFIFMRFAERGDLLTYIQEVGFVKEKQAK 287

Query: 146 YFLYQILRGLKYIHSANVLHRDLKPSNLLINTTCDLKICDFGLARIADPEHDHTGFLTEY 205
            + YQ+   L Y+HS +V HRDLK  N+L+++  ++K+ DFG A     E         Y
Sbjct: 288 IWFYQMTTALNYLHSYDVAHRDLKCENILLSSHFNVKLADFGFACACITESGEKYMSRTY 467

Query: 206 VATRWYRAPEIMLNSKGYTKSIDIWSVG 233
             +  Y APEI+  +    K  D WS+G
Sbjct: 468 CGSAAYAAPEIVYGAPYAPKVADAWSLG 551
>12453
          Length = 680

 Score = 63.9 bits (154), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 37/105 (35%), Positives = 56/105 (53%), Gaps = 3/105 (2%)
 Frame = +3

Query: 232 VGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINMKARN--YLQ-SLPSK 288
           VGCI  EM   RP+FPG    D+L+ I   LG+P+++ L  I    +RN  +L  +LP  
Sbjct: 6   VGCIFYEMACGRPLFPGSTVEDELHLIFKTLGTPTEDSLPSI----SRNPDFLALNLPHY 173

Query: 289 TKVAWAKLFPKSDSKALDLLDRMLTFNPNKRITVEEALAHPYLEQ 333
              A   + P+ DS  LDLL + L +N   R++  ++L H +   
Sbjct: 174 QGEALITIAPRLDSDGLDLLAKFLKYNAKIRVSAADSLKHSFFNS 308
>30755
          Length = 1137

 Score = 63.5 bits (153), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 32/98 (32%), Positives = 55/98 (56%)
 Frame = +2

Query: 146 YFLYQILRGLKYIHSANVLHRDLKPSNLLINTTCDLKICDFGLARIADPEHDHTGFLTEY 205
           ++  +I+  L Y+HS  +++RDLK  NLL++    +K+ DFGL +  D  +  T     +
Sbjct: 44  FYGAEIISALGYLHSQGIIYRDLKLENLLLDKDGHIKVADFGLCK-EDITYGRT--TKTF 214

Query: 206 VATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNR 243
             T  Y APE+ L+   Y +++D W  G ++ EM+  R
Sbjct: 215 CGTPEYLAPEV-LDDNDYGRAVDWWGTGVVMYEMICGR 325
>11185
          Length = 473

 Score = 63.5 bits (153), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 38/134 (28%), Positives = 62/134 (46%), Gaps = 21/134 (15%)
 Frame = +1

Query: 147 FLYQILRGLKYIHSANVLHRDLKPSNLLINTTCDLKICDFGLARIADPEHDHTGFLTEYV 206
           F   ++ GL YIHS  +L  DL+PS +L++T+  LK  DFGL+++     +   F     
Sbjct: 16  FGIHLVTGLHYIHSLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEA 195

Query: 207 ATRW-------------------YRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIF- 246
             +W                   Y APE+   ++    S D+W++GC+  EM S   +  
Sbjct: 196 GDQWNIQSAEEMMKQVPTSGSPTYMAPEVFQGAEPSIMS-DLWALGCVFYEMFSGSRLSA 372

Query: 247 -PGKHYLDQLNHIL 259
            P   +L+ L  +L
Sbjct: 373 KPSPEFLNLLESLL 414
>31885
          Length = 529

 Score = 62.4 bits (150), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 43/136 (31%), Positives = 70/136 (51%), Gaps = 7/136 (5%)
 Frame = -2

Query: 118 DVYIVQDL-METDL-YKLLKSQQLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLI 175
           D+++V DL +  DL Y + +      D + ++L Q+   L Y+ S  ++HRD+KP N+L+
Sbjct: 450 DLFMVVDLFLGGDLRYHMQQEVSFREDCVKFYLCQLALVLDYLRSQKIVHRDIKPDNILL 271

Query: 176 NTTCDLKICDFGLA-RIADPEHDHTGFLTEYVATRWYRAPEI----MLNSKGYTKSIDIW 230
           +      + DF +A ++ D E       T    TR Y APE+    +   +GY   +D W
Sbjct: 270 DEQGHCHVTDFNIATQLEDDE-----LATSTSGTRPYMAPEVYGVAINERRGYGFPVDWW 106

Query: 231 SVGCILAEMLSNRPIF 246
           S+G  L E+L  R  F
Sbjct: 105 SLGVSLFELLKKRRPF 58
>07940
          Length = 1336

 Score = 62.0 bits (149), Expect = 4e-10,   Method: Compositional matrix adjust.
 Identities = 37/113 (32%), Positives = 58/113 (51%)
 Frame = -3

Query: 129 DLYKLLKSQQLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLINTTCDLKICDFGL 188
           D+ K+L  + L +     + YQ+ RG++Y+ S   +HRDL   N+L+     LKI DFGL
Sbjct: 371 DMLKMLTPKDLIS-----YAYQVARGMEYLASKQCIHRDLAARNVLVAEEYVLKIADFGL 207

Query: 189 ARIADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLS 241
            R       +       +  +W  APE + + K YT   D+WS G +L E+ +
Sbjct: 206 TRNLQQFDYYRKTTDGRLPVKWM-APEALFDRK-YTSKSDVWSYGVLLWEIFT 54
>27546
          Length = 426

 Score = 60.8 bits (146), Expect = 9e-10,   Method: Compositional matrix adjust.
 Identities = 36/106 (33%), Positives = 57/106 (53%), Gaps = 3/106 (2%)
 Frame = -1

Query: 88  REIQILLRFRHENVIGIRDIL-RAPTLEAMRDVYIVQDLMETD--LYKLLKSQQLSNDHI 144
           RE++IL R  H N+I I  IL R P       ++I     E    L  + K+  +     
Sbjct: 333 RELEILTRLDHPNIIQIHSILQRGPK------IFIFMRYAEKGDMLSHIKKTGPIDEAQT 172

Query: 145 CYFLYQILRGLKYIHSANVLHRDLKPSNLLINTTCDLKICDFGLAR 190
             + +Q+ + L+Y+HS ++ HRDLK  N+L++   ++KI DFG AR
Sbjct: 171 KVWFFQMAKALQYLHSHDIAHRDLKCENILLSKRLNVKIADFGFAR 34
>00715
          Length = 1788

 Score = 59.7 bits (143), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 52/182 (28%), Positives = 75/182 (41%), Gaps = 29/182 (15%)
 Frame = +1

Query: 96  FRHENVIGIRDILRAPTLEAMRDVYIVQDLMETDLYKLLKSQQLSNDHI--------CYF 147
            RH NV+    IL A +L    D       +  +    L  Q + NDH            
Sbjct: 97  LRHVNVV---SILGATSLHRFED----GAWLAMEYVGPLNLQTILNDHQQDIDSSMRLSL 255

Query: 148 LYQILRGLKYIHSANVLHRDLKPSNLLINTTCDLKICDFGLARIADPEHDHTG------- 200
             Q+ RGL Y+HS N++H DLKP+N L+     L+I DFG      P     G       
Sbjct: 256 ALQMARGLHYLHSINIVHLDLKPANCLLTRDLKLRIADFGCCHQLTPTGLDMGEREGGMA 435

Query: 201 ------------FLTEYVATRWYRAPEIMLNSKGYTKSI--DIWSVGCILAEMLSNRPIF 246
                       +  E   T  YRAPE++   KG   S+  D++S+G  L +M + +  +
Sbjct: 436 GNELELTPVQGAWKNELAGTLAYRAPELL---KGLQPSVRSDVYSLGITLWQMCTRQGPY 606

Query: 247 PG 248
            G
Sbjct: 607 EG 612
>21079
          Length = 878

 Score = 59.3 bits (142), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 37/106 (34%), Positives = 56/106 (52%), Gaps = 2/106 (1%)
 Frame = +1

Query: 139 LSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLI--NTTCDLKICDFGLARIADPEH 196
           L+     +F+ QI  G+ Y+H+ ++LH DLKP N+L   + +  +KI DFGLAR   P  
Sbjct: 118 LTERDCVHFVRQICSGVGYMHTQSILHLDLKPENVLCVSDNSNQIKIIDFGLARFYKPGD 297

Query: 197 DHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSN 242
                L     T  + APE+ +N      + D+WS+G I   +LS 
Sbjct: 298 S----LQVLFGTPEFIAPEV-VNYDEINFTTDMWSIGVICYILLSG 420
>18401
          Length = 463

 Score = 58.5 bits (140), Expect = 4e-09,   Method: Compositional matrix adjust.
 Identities = 42/155 (27%), Positives = 72/155 (46%), Gaps = 20/155 (12%)
 Frame = -3

Query: 206 VATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFP---GKHYLDQLNHILGIL 262
           V+TR YRAPE++L   G++   D+WSVGCI+ E+ +   +F     K +L  +  ILG L
Sbjct: 449 VSTRHYRAPEVILEL-GWSHPCDVWSVGCIMFELYTGYTLFQTHDNKEHLAMMERILGSL 273

Query: 263 GSPSQEDLNCIINMKARNYLQ----SLPSKTKVA------------WAKLFPKSDSKAL- 305
                         K + Y       +P ++ +A            + K     D + L 
Sbjct: 272 ------PYRMAKKTKKQKYFHHGRLDVPERSSMARYVRENTKPLLRYVKDRENKDHQQLF 111

Query: 306 DLLDRMLTFNPNKRITVEEALAHPYLEQYYDPTDE 340
           DL+ ++L +  + R ++ +AL HP+   Y+   D+
Sbjct: 110 DLMKKLLAYEASSRYSLLQALQHPFFSPYHHNRDQ 6
>27405
          Length = 532

 Score = 58.2 bits (139), Expect = 6e-09,   Method: Compositional matrix adjust.
 Identities = 35/112 (31%), Positives = 60/112 (53%), Gaps = 2/112 (1%)
 Frame = -3

Query: 121 IVQDLMET-DL-YKLLKSQQLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLINTT 178
            + DLM   DL Y L +    +   + ++  +++ GL+++HS  V++RDLKP+N+L++  
Sbjct: 323 FILDLMNGGDLHYHLSQHGVFTEKEVRFYAAEVMLGLEHMHSRFVVYRDLKPANILLDEN 144

Query: 179 CDLKICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIW 230
             ++I D GLA     +  H       V T  Y APE+++  + Y  S D W
Sbjct: 143 GHVRISDLGLACDFSKKKPHAS-----VGTHGYMAPEVLMKGQAYDSSAD-W 6
>12786
          Length = 460

 Score = 57.8 bits (138), Expect = 7e-09,   Method: Compositional matrix adjust.
 Identities = 40/133 (30%), Positives = 65/133 (48%), Gaps = 21/133 (15%)
 Frame = -3

Query: 135 KSQQLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLINTTCDLKICDFGLARIADP 194
           + Q L    I ++  ++LR +K +H+  V+H DLKP+N ++    +LK+ DFG+A     
Sbjct: 431 QEQGLDRMMIKFYWREMLRAVKALHNEGVIHSDLKPANFML-VAGNLKLIDFGIANTL-- 261

Query: 195 EHDHTGFLTEY-VATRWYRAPEIMLNS--------------------KGYTKSIDIWSVG 233
           + D T  L +  V T  Y +PE ++ +                    K   +S D+WS+G
Sbjct: 260 QQDKTSVLKDSRVGTPSYMSPEAIMAACDDSADDSMEEDGHRTKPKYKVGVRS-DVWSLG 84

Query: 234 CILAEMLSNRPIF 246
           CIL  M+  R  F
Sbjct: 83  CILYNMVYGRTPF 45
>00392
          Length = 668

 Score = 57.4 bits (137), Expect = 9e-09,   Method: Compositional matrix adjust.
 Identities = 46/164 (28%), Positives = 80/164 (48%), Gaps = 5/164 (3%)
 Frame = +3

Query: 84  QRTLREIQILLRFRHENVIGIRDILRAPTLEAMRDVYIVQDLMETDLYKL-LKSQQLSND 142
           QR   E ++L   +H N++   D          + + +V +LM +   K  LK  +  N 
Sbjct: 66  QRFKEEAEMLKELQHPNIVRFFDYWEEHNHRNRKVIILVTELMTSGTLKTYLKRFKKPNV 245

Query: 143 HICY-FLYQILRGLKYIHSAN--VLHRDLKPSNLLINT-TCDLKICDFGLARIADPEHDH 198
            I   +  Q+L+GL ++H+    V+HRDLK  N+ I   T  +KI D GLA + +     
Sbjct: 246 KILKNWCRQVLKGLYFLHTRTPPVIHRDLKCDNIFITGPTGSVKIGDLGLATLKN----- 410

Query: 199 TGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSN 242
             F    + T  + APE  +  + Y +++D+++ G  + EM S+
Sbjct: 411 QSFAKSVIGTPEFMAPE--MYEEHYDEAVDVYAFGMCMLEMASS 536
>14116
          Length = 1017

 Score = 57.4 bits (137), Expect = 9e-09,   Method: Compositional matrix adjust.
 Identities = 57/209 (27%), Positives = 96/209 (45%), Gaps = 11/209 (5%)
 Frame = -1

Query: 44  TQLQYIGEGAYGMVSSAYDHVRKTR----VAIKKI---SPFEHQTYCQRTLREIQILLRF 96
           T  + IG+G +G V   +  + + +    VA+K +   +P E +   Q  L+E  I+  F
Sbjct: 627 TMGEEIGKGNFGCVKRGFLTLPEQKGDILVAVKTLHNNNPREIEL--QSFLQEALIMKDF 454

Query: 97  RHENVIGIRDILRAPTLEAMRDVYIVQDLMETDLYKLLKSQQLS---NDHICYFLYQILR 153
            H NV+ +  I     L+ M  V ++  +   DL   ++  Q      D I Y +  I R
Sbjct: 453 HHSNVLTLIGI--CLNLDDMPLV-VLPFMKHGDLLTYIRDDQHQPTIKDLIMYGV-DIAR 286

Query: 154 GLKYIHSANVLHRDLKPSNLLINTTCDLKICDFGLAR-IADPEHDHTGFLTEYVATRWYR 212
           G+ Y+     +HRDL   N +++    +K+ DFGLAR I + E+  +      +  +W  
Sbjct: 285 GMDYLAGLKFVHRDLAARNCMLDEDFHVKVADFGLARDIYEKEYYSSENKKAKLPVKWMA 106

Query: 213 APEIMLNSKGYTKSIDIWSVGCILAEMLS 241
                L    Y    D+WS G +L E+L+
Sbjct: 105 LES--LEKGNYDSKTDVWSYGVVLWELLT 25
>11780
          Length = 1713

 Score = 56.6 bits (135), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 47/193 (24%), Positives = 91/193 (47%), Gaps = 7/193 (3%)
 Frame = +3

Query: 47  QYIGEGAYGMVSSAYDHVRKTRVAIKKISPFEHQTYCQRTLREIQILLRFRHENVIGIRD 106
           + IG+G +G V       R   VAIK++   +     Q  L+E  ++   RH+N++ +  
Sbjct: 615 EAIGKGDFGDVYKGM--YRGQPVAIKQLKDKDRGE--QSFLQEASVMTSLRHDNLVRLIG 782

Query: 107 ILRAPTLEAMRDVYIVQDLM-ETDLYKLLKSQQLS----NDHICYFLYQILRGLKYIHSA 161
           ++   T      +++V + M + +L + L+S+  S     D I  F       ++Y+ S 
Sbjct: 783 VVLGET------IFLVTEFMGKGNLVEYLRSRGRSVITKKDQI-NFATDTCAAMEYLESK 941

Query: 162 NVLHRDLKPSNLLINTTCDLKICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLNSK 221
            ++HRDL   N+L++     K+ DFGLA+  D       F  ++       APE +  +K
Sbjct: 942 RLVHRDLAARNVLVHDDGKAKVSDFGLAKFGDFSQTSVKFPIKWT------APEALRENK 1103

Query: 222 GY--TKSIDIWSV 232
            +   + +++W +
Sbjct: 1104IH*QVRHVELWHI 1142
>18996
          Length = 491

 Score = 56.2 bits (134), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 30/82 (36%), Positives = 47/82 (57%)
 Frame = +2

Query: 164 LHRDLKPSNLLINTTCDLKICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLNSKGY 223
           +HRDL   N+L++ +C +KI DFGLA+ A+ +  + G     +  +WY +PE +   K +
Sbjct: 2   IHRDLAARNILVDRSC-VKISDFGLAQFANADGYYYGISQRDIPIKWY-SPEAIETCK-F 172

Query: 224 TKSIDIWSVGCILAEMLSNRPI 245
           +   D+WS G  L EM S   I
Sbjct: 173 SSYSDVWSYGVTLFEMFSRGEI 238
>26909
          Length = 394

 Score = 55.8 bits (133), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 36/113 (31%), Positives = 54/113 (47%), Gaps = 16/113 (14%)
 Frame = +2

Query: 235 ILAEMLSNRPIF---------PGKHYLDQLNHILGILGSPSQEDLNCIINMKARNYLQSL 285
           I AE+L++ PIF            ++ DQL+ I  ++G P ++D   I  M     L   
Sbjct: 2   IFAELLTSEPIFHCRQEDIKTSNPYHHDQLDRIFNVMGFPQEKDWEDIRRMPEHQQLTKD 181

Query: 286 PSKTKVAWAKLFP-------KSDSKALDLLDRMLTFNPNKRITVEEALAHPYL 331
             ++      L         K+DSKA  LL ++LT +P KRIT E+A+  PY 
Sbjct: 182 FKRSSYVNCNLMKYMEKHKVKADSKAFHLLQKLLTMDPVKRITSEQAMKDPYF 340
>05084
          Length = 1324

 Score = 55.8 bits (133), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 47/144 (32%), Positives = 71/144 (49%), Gaps = 9/144 (6%)
 Frame = +2

Query: 246 FPGKHYLDQLNHILGILGSPSQEDLNCIINMKARNYLQ-SLPSKTKVAWAKLF-PKSDSK 303
            PG   +DQL  I+ +LG+P++E     I     NY +   P      W K+F P++  +
Sbjct: 2   LPGDSGVDQLVEIIKVLGTPTREQ----IREMNPNYSEFKFPQIKAHPWTKVFRPRTPPE 169

Query: 304 ALDLLDRMLTFNPNKRITVEEALAHPYLEQYYDPTDE-PVAEE-P--FTF-DMELDDLPK 358
           A+ L+ R+L + P+ RI   EA AH + ++  DP    P   E P  F+F  MEL   P+
Sbjct: 170 AIQLVSRLLEYTPSARIQPMEACAHAFFDELRDPASRLPNGRELPPLFSFTQMELAIAPQ 349

Query: 359 ERLKELI--FQETARFQPGAPEGP 380
                LI     +A  +P A +GP
Sbjct: 350 LN-ASLIPPHARSANTEPSATQGP 418
>17300
          Length = 480

 Score = 54.3 bits (129), Expect = 8e-08,   Method: Compositional matrix adjust.
 Identities = 37/134 (27%), Positives = 62/134 (46%), Gaps = 15/134 (11%)
 Frame = +1

Query: 151 ILRGLKYIHSANVLHRDLKPSNLLINTTCDLKICDFGLARIADPEHDHTGFLTE--YVAT 208
           I  G+  +     +HRDL   N+L+N     K+ DFGL+R  + +     + T+   +  
Sbjct: 1   ISSGMGXLADMGYVHRDLAARNILVNEILVCKVADFGLSREIESDTTEGAYTTKGGKIPV 180

Query: 209 RWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNH----------- 257
           RW  APE +   K +T + D+WS G ++ E++S    +  + Y +  N            
Sbjct: 181 RW-TAPEAIAYRK-FTSASDVWSFGVVMWEVMS----YGERPYWNWSNQDVIKAVEKGYR 342

Query: 258 --ILGILGSPSQED 269
             + G+ GSPS  D
Sbjct: 343 LPLHGLSGSPSSTD 384
>19301
          Length = 712

 Score = 54.3 bits (129), Expect = 9e-08,   Method: Compositional matrix adjust.
 Identities = 42/150 (28%), Positives = 73/150 (48%), Gaps = 4/150 (2%)
 Frame = +2

Query: 44  TQLQYIGEGAYGMVSSAYDHVRKTRVAIKKISPFEHQTYCQRTLREIQI--LLRFRHENV 101
           T L+++G GA G V      +    VA+KK+          R ++E  I  L +  H N+
Sbjct: 314 TDLEWLGSGAQGAV--FLGKLCAEEVAVKKV----------RDIKETDIRNLRKLNHPNI 457

Query: 102 IGIRDIL-RAPTLEAMRDVYIVQDLMETDLYKLLK-SQQLSNDHICYFLYQILRGLKYIH 159
           I  + +  +AP         I++      LY++L+  +++    +  +  QI  G+ Y+H
Sbjct: 458 ISFKGVCTQAPCY-----CIIMEYCPYGQLYEVLRDGKEIPPALVLDWSKQIASGMNYLH 622

Query: 160 SANVLHRDLKPSNLLINTTCDLKICDFGLA 189
           S  ++HRDLK  N+L+     +KI DFG +
Sbjct: 623 SHKIIHRDLKSPNVLVAKNDVVKISDFGTS 712
>26711
          Length = 405

 Score = 53.9 bits (128), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 35/99 (35%), Positives = 56/99 (56%), Gaps = 2/99 (2%)
 Frame = -2

Query: 150 QILRGLKYIHSANVLHRDLKPSNLLINTTC--DLKICDFGLARIADPEHDHTGFLTEYVA 207
           Q+L  L+++H+  V+H DLKPSNLL++      +++ DFGLAR   P  +   FL     
Sbjct: 392 QVLDILQHVHAQGVVHMDLKPSNLLLSGDKLDSVQLIDFGLARKLYPPQET--FLNH--G 225

Query: 208 TRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIF 246
           T  + +PE  L+ K  + + D+W VG +   +LS +  F
Sbjct: 224 TPGFTSPE-ALDVKPISTASDVWGVGVLAYILLSGQSPF 111
>21433
          Length = 590

 Score = 53.5 bits (127), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 38/100 (38%), Positives = 54/100 (54%)
 Frame = +2

Query: 145 CYFLYQILRGLKYIHSANVLHRDLKPSNLLINTTCDLKICDFGLARIADPEHDHTGFLTE 204
           CY +YQ+   L+Y H   V+HRD+KP NLL+    DLKI DFG +      H  +   T 
Sbjct: 179 CY-IYQLSSALEYCHYRKVIHRDIKPENLLLGLKGDLKIADFGWS-----VHAPSSRRTT 340

Query: 205 YVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRP 244
              T  Y  PE M+  K + +++D+WS+G +  E L   P
Sbjct: 341 MCGTLDYLPPE-MVEGKTHDENVDLWSLGVLCYEFLVGTP 457
>28157
          Length = 400

 Score = 50.8 bits (120), Expect = 9e-07,   Method: Compositional matrix adjust.
 Identities = 45/133 (33%), Positives = 67/133 (50%), Gaps = 12/133 (9%)
 Frame = +3

Query: 69  VAIKKI-SPFEHQTYCQRTLREIQILLRFRHENVIGIRDILRAPTLEAMRD--VYIVQDL 125
           VA+K+I S  E +++    ++E++ L R  H N++ +          A RD  V +V + 
Sbjct: 9   VAVKRIESEQEKKSF----MQELKQLSRVSHPNIVCLYG--------ACRDHPVCLVMEY 152

Query: 126 MET-DLYKLLKSQ----QLSNDHICYFLYQILRGLKYIHSAN---VLHRDLKPSNLL-IN 176
            E   LY +L       Q +  H   +L Q   G++Y+H      ++HRDLKP NLL I 
Sbjct: 153 AEGGSLYNVLHGSGPQPQYTAAHAMNWLLQCALGVEYLHGMKPKALIHRDLKPPNLLLIQ 332

Query: 177 TTCDLKICDFGLA 189
               LKICDFG A
Sbjct: 333 CGTKLKICDFGTA 371
>01106
          Length = 878

 Score = 50.1 bits (118), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 43/148 (29%), Positives = 70/148 (47%), Gaps = 14/148 (9%)
 Frame = +3

Query: 42  RYTQLQYIGEGAYGMVSSAYDHVRKTRVAIKKISPFEHQTYCQRTLREIQILLRFRHENV 101
           RY  ++ +G G +  V   +D   K  VA+K +   +H  Y +  L E+++L   R  +V
Sbjct: 321 RYHVIRKLGWGHFSTVWLCWDLTCKRFVALKVVKSAQH--YTETALDEVKLLKCVRESDV 494

Query: 102 IGIRDILRAPTLEAMRDVYI-------VQDLMETDLYKLLKSQQLSN------DHICYFL 148
               D  RA  ++ + D  I       V  + E   Y LLK    SN       ++   +
Sbjct: 495 A---DPARAKCVQLLDDFKISGVNGTHVAMVFEVLGYNLLKLIIRSNYQGIPIHNVKLII 665

Query: 149 YQILRGLKYIHS-ANVLHRDLKPSNLLI 175
            Q+L GL Y+H+   ++H D+KP N+LI
Sbjct: 666 RQVLEGLSYMHAKCRIIHTDIKPENILI 749
>16708
          Length = 1397

 Score = 49.3 bits (116), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 53/226 (23%), Positives = 98/226 (43%), Gaps = 27/226 (11%)
 Frame = -1

Query: 46   LQYIGEGAYGMVSSAYDHVRKTRVAIKKISPFEHQTYCQRTLREIQILLR----FRHENV 101
            LQ +G+G +G V  A       + A+K          C  +L E++ L R    F    +
Sbjct: 1388 LQVLGKGVFGKVYEARLLSTHEKAALKT------SILCHHSLDEVEALGRIEGGFYLAQM 1227

Query: 102  IGIR-DILRAPTLEAMRDVYIVQDLMETDLYKLLKSQQL----SNDH-ICYFLYQILRGL 155
             G     L  P +  +   Y +  L   ++Y   K++++    SN   +C    Q +  L
Sbjct: 1226 FGAWVTCLPFPKMNILLHFYEMGPL--CNVYAHYKNKEMPIRWSNPAMVCCIAGQXVCAL 1053

Query: 156  KYIHSANVLHRDLKPSNLLINTTCDLKICDFGLARI----ADPEHDHTGFLTEYVATRWY 211
            ++IH   V+H D+K  N+L++   + K+ D+G+A++      P   H+   T    T + 
Sbjct: 1052 EHIHELGVVHMDVKADNVLVDAHGNCKLTDYGIAQLYKVYPAPTETHSSGCTNK-RTFYT 876

Query: 212  RAPEIMLNSKGYTKSID------------IWSV-GCILAEMLSNRP 244
            R P  M  S+ +++  D            +W++ G +L  +  +RP
Sbjct: 875  RPPATMTPSERFSEEGDGIGTDYFRLGQMLWTLTGAVLLHVWVSRP 738
>07291
          Length = 833

 Score = 48.9 bits (115), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 32/112 (28%), Positives = 56/112 (50%)
 Frame = +1

Query: 136 SQQLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLINTTCDLKICDFGLARIADPE 195
           S+ L+   +  F  QI  G+ Y+    V+HR+L   N ++     L++ D+G+     P+
Sbjct: 31  SKMLTVVQLLDFGRQIADGMAYLQEVKVVHRNLAARNCIVTEDGRLQLSDYGVTGSLFPQ 210

Query: 196 HDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFP 247
             +T   +       + APE + N    +KS D+W+ G +L E+L+ R I P
Sbjct: 211 SYYTADDSPARDLVKWMAPETIDNFHFSSKS-DVWAFGVVLWELLT-RGITP 360
>20640
          Length = 1492

 Score = 46.2 bits (108), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 25/78 (32%), Positives = 38/78 (48%)
 Frame = +1

Query: 164 LHRDLKPSNLLINTTCDLKICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLNSKGY 223
           +HRDL   N L+     +KI DFGLAR       + G   + +  RW     I+ N   +
Sbjct: 10  VHRDLATRNCLVGHDLVVKISDFGLARSVHSVDYYRGSEHDAIPIRWMPLEAILYNK--F 183

Query: 224 TKSIDIWSVGCILAEMLS 241
           +   D+WS G +L E+ +
Sbjct: 184 STQSDVWSFGVVLWEIFA 237
>11404
          Length = 563

 Score = 45.8 bits (107), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 41/144 (28%), Positives = 73/144 (50%), Gaps = 8/144 (5%)
 Frame = +1

Query: 40  GPRYTQLQYIGEGAYGMVSSAYDHVRKTRVAIKKI---SPFEHQTYCQRTLREIQILLRF 96
             RY     IG+G++G V  AYDH    +VAIK I    PF +Q   Q  ++ ++++ R 
Sbjct: 136 ADRYEIDSLIGKGSFGQVVKAYDHTDNEQVAIKIIKNKKPFLNQA--QIEVKLLEMMNRH 309

Query: 97  RHENVIGIRDILRAPTLEAMRDVYIVQDLMETDLYKLLKSQQ---LSNDHICYFLYQILR 153
             +N   I  + R     +   + +V +L+  +LY LL++     +S +    F  Q+  
Sbjct: 310 DTDNKYYIVRLKRHFMFRSH--LCLVFELLSYNLYDLLRNTNFRGVSLNLTRKFAQQLCT 483

Query: 154 GLKYIHS--ANVLHRDLKPSNLLI 175
            L ++ +   +++H DLKP N+L+
Sbjct: 484 ALLFLATPEMSIIHCDLKPENILL 555
>00638
          Length = 1595

 Score = 45.1 bits (105), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 29/89 (32%), Positives = 50/89 (56%), Gaps = 1/89 (1%)
 Frame = +2

Query: 89  EIQILLRFRH-ENVIGIRDILRAPTLEAMRDVYIVQDLMETDLYKLLKSQQLSNDHICYF 147
           EI+IL   R   NVI +  I++ P   +     I + +  TD  +L   Q  ++  I ++
Sbjct: 266 EIKILENLRGGTNVITLLAIVKDPV--SRTPALIFEHVNNTDFKQLY--QTFTDYDIRFY 433

Query: 148 LYQILRGLKYIHSANVLHRDLKPSNLLIN 176
           LY++++ L + HS  ++HRD+KPS  L+N
Sbjct: 434 LYELMKALDFCHSMGIMHRDVKPSPPLVN 520
>14477
          Length = 493

 Score = 45.1 bits (105), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 37/155 (23%), Positives = 77/155 (49%), Gaps = 5/155 (3%)
 Frame = -1

Query: 49  IGEGAYGMVSSAYDHV--RKTRVAIKKISPFEHQTYCQRTL-REIQILLRFRHENVIGIR 105
           +G G +G V      +  R+  VAIK +   +     Q  L +E +++ +  H +++ + 
Sbjct: 466 LGAGNFGSVMKGVCRLDDREIPVAIKVLKNADLDPSVQSELIKEAEVMKKMDHMHIVRLI 287

Query: 106 DILRAPTLEAMRDVYIVQDLMETD-LYKLL-KSQQLSNDHICYFLYQILRGLKYIHSANV 163
            +    T+       +V +L +   L K L K++ L   +I   ++Q+ +G++Y+ +   
Sbjct: 286 GLCEGETM------MLVLELAKLGPLNKFLPKNKHLPLWNILELMWQVSQGMEYLEANKF 125

Query: 164 LHRDLKPSNLLINTTCDLKICDFGLARIADPEHDH 198
           +HRDL   N+L+      KI DFG+++    E+++
Sbjct: 124 VHRDLAARNILLCDEHFAKISDFGMSKTLSRENNY 20
>13078
          Length = 773

 Score = 44.3 bits (103), Expect = 8e-05,   Method: Compositional matrix adjust.
 Identities = 32/141 (22%), Positives = 61/141 (43%), Gaps = 24/141 (17%)
 Frame = -1

Query: 220 SKGYTKSIDIWSVGCILAEMLSNRPIFP---GKHYLDQLNHILGILGSPSQEDLNCIINM 276
           S G+++  D+WS+GCI+ E+ +   +F     K +L  +  ILG L             M
Sbjct: 755 SWGWSQPCDVWSIGCIMFELYTGYTLFQTHDNKEHLAMMERILGSL----------PYRM 606

Query: 277 KARNYLQSLPSKTKVAW-----AKLFPKSDSKAL----------------DLLDRMLTFN 315
             +   Q      ++ W     A  + + + K L                DL+D+ML++ 
Sbjct: 605 AKKTKKQKYFYHGRLDWDEKSSAGRYVRDNVKPLRRYVKDPDNEDHQQLFDLMDKMLSYE 426

Query: 316 PNKRITVEEALAHPYLEQYYD 336
            + R ++ +A+ HP+  + Y+
Sbjct: 425 VSTRYSLRQAMRHPFFRKLYE 363
>07836
          Length = 1478

 Score = 43.9 bits (102), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 46/188 (24%), Positives = 82/188 (43%), Gaps = 17/188 (9%)
 Frame = -1

Query: 69   VAIKKISPFEHQTYCQRTLREIQILLRFRHENVIGI--RDILRAPTLEAMRDVYIVQDLM 126
            VA+K     E  ++ + T  E+   +  RHEN++G    DI       +   ++++ D  
Sbjct: 1469 VAVKIFFTTEEASWFRET--ELYQTVLLRHENILGFIAADI---KGTGSWTQLFLITDYH 1305

Query: 127  ET-DLYKLLKSQQLSNDHICYFLYQILRGLKYIH--------SANVLHRDLKPSNLLINT 177
            E   L+  L S+ L +  +    +  + GL ++H           + HRD+K  N+L+  
Sbjct: 1304 ENGSLHDYLLSRVLDSSEMLALAHSAICGLAHLHIEIFGTRGKPAIAHRDIKSKNILVKK 1125

Query: 178  TCDLKICDFGLARIADPEHDHTGFL-TEYVATRWYRAPEI---MLNSKGYT--KSIDIWS 231
                 I D GLA     E +           T+ Y APE+   +LN K +   K  D+++
Sbjct: 1124 NGTCCIADLGLAVRYISESNEVDVAPNPRQGTKRYMAPEVLEMLLNVKNFDAFKQADMYA 945

Query: 232  VGCILAEM 239
             G ++ E+
Sbjct: 944  FGLVMWEI 921
>02638
          Length = 1490

 Score = 43.1 bits (100), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 21/64 (32%), Positives = 34/64 (53%)
 Frame = +1

Query: 201 FLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILG 260
           F  + + T  + APE+ L  + Y ++ D+WSVGC++ EM + RP +      + L  I  
Sbjct: 4   FQGQLLGTIAFMAPEV-LRGESYGRACDVWSVGCVMIEMCTCRPPWNSHDISNHLALIFK 180

Query: 261 ILGS 264
           I  S
Sbjct: 181 IASS 192
>22005
          Length = 873

 Score = 42.0 bits (97), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 34/95 (35%), Positives = 47/95 (49%)
 Frame = +1

Query: 146 YFLYQILRGLKYIHSANVLHRDLKPSNLLINTTCDLKICDFGLARIADPEHDHTGFLTEY 205
           Y   QI  G+ Y+   + +HRDL    +   TT    I DFGLAR       + G   + 
Sbjct: 454 YISQQISAGMAYLAQKDYVHRDLATRTVXSRTT-*S*ISDFGLARSVHSVDYYRGSEQDA 630

Query: 206 VATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEML 240
           +  RW    E +L SK  T+S D+WS G +L E+L
Sbjct: 631 IPIRWM-PLEAILYSKFSTQS-DVWSFGVVLWEIL 729
>37602
          Length = 804

 Score = 41.6 bits (96), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 19/58 (32%), Positives = 34/58 (58%)
 Frame = -1

Query: 129 DLYKLLKSQQLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLINTTCDLKICDF 186
           D+Y +  +  L+   I +   + L+GL Y+H    +HRD+K +N+L+    D+K+ DF
Sbjct: 252 DIYHV--TGPLTEPQIAFVCRETLKGLHYLHRRGKMHRDIKGANILLTEEGDVKLADF 85
>32359
          Length = 928

 Score = 41.6 bits (96), Expect = 6e-04,   Method: Compositional matrix adjust.
 Identities = 38/152 (25%), Positives = 68/152 (44%), Gaps = 10/152 (6%)
 Frame = -1

Query: 43  YTQLQYIGEGAYGMVSSAYDHVRKTRVAIKKI---SPFEHQTYCQRTLREIQILLRFRHE 99
           YT  + IG G++G+V  A        VAIKK+     F++        RE+QI+ +  H+
Sbjct: 424 YTDAKVIGNGSFGVVYQAKLVDTSELVAIKKVLQDKRFKN--------RELQIMRKLEHQ 269

Query: 100 NVIGIRDILRAPTLEAMRDVYI--VQDLMETDLYKLLKSQQLSND-----HICYFLYQIL 152
           N++ ++    +   E   +V++  V + +   +Y++ +    S       +I  ++YQ+ 
Sbjct: 268 NIVKLKFFFYSSG-EKKDEVFLNLVLEYVPETVYRVARHYSKSKQTIPILYIKLYMYQLF 92

Query: 153 RGLKYIHSANVLHRDLKPSNLLINTTCDLKIC 184
           R L YIH           S   +  T  LK C
Sbjct: 91  RSLAYIH-----------SQACVTATSSLKTC 29
>20559
          Length = 430

 Score = 40.0 bits (92), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 22/70 (31%), Positives = 38/70 (54%), Gaps = 1/70 (1%)
 Frame = -2

Query: 42  RYTQLQYIGEGAYGMVSSAYDHVRKTRVAIKKIS-PFEHQTYCQRTLREIQILLRFRHEN 100
           +Y +L+ IGEG YG V  A +      VA+K++    + +      LREI +L   +H N
Sbjct: 372 KYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKHRN 193

Query: 101 VIGIRDILRA 110
           ++ + D+L +
Sbjct: 192 IVRLHDVLHS 163
>17253
          Length = 483

 Score = 39.3 bits (90), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 16/51 (31%), Positives = 30/51 (58%)
 Frame = -1

Query: 147 FLYQILRGLKYIHSANVLHRDLKPSNLLINTTCDLKICDFGLARIADPEHD 197
           F   + RG+ ++ +  ++HRD+   N+LI+     K+ DFGL+R    ++D
Sbjct: 195 FALHVARGMAHVANNKIVHRDVAARNVLISERNVCKVSDFGLSRRVGDQND 43
>37063
          Length = 455

 Score = 39.3 bits (90), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 30/78 (38%), Positives = 40/78 (51%), Gaps = 9/78 (11%)
 Frame = -2

Query: 168 LKPSNLL---INTTCDLKICDFGLARIADPEHDHTGF--LTEYVATRWYRAPEIMLNSKG 222
           LKP N+L   ++    LKICDF LA   + + D T    L   V +  Y APE++    G
Sbjct: 454 LKPENILCEHLDEVVPLKICDFDLASGINCDGDGTKTPELLTPVGSAEYMAPEVVDAWVG 275

Query: 223 ----YTKSIDIWSVGCIL 236
               Y K  D+WS+G IL
Sbjct: 274 ESFSYDKRCDMWSLGIIL 221
>17975
          Length = 449

 Score = 38.5 bits (88), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 33/127 (25%), Positives = 63/127 (49%), Gaps = 5/127 (3%)
 Frame = +3

Query: 68  RVAIKKISPFEHQTYCQRTL-REIQILLRFRHENVIGIRDILRAPTLEAMRDVYIVQDLM 126
           +VA+K I   +     +  L +E++ +   +H NV+ + +++   T      +Y++ +L 
Sbjct: 48  KVAVKVIDKTKLDEVSRSHLFQEVRCMKLVQHPNVVRLYEVIDTQT-----KLYLILELG 212

Query: 127 ET-DLYKLL--KSQQLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLINTTCDL-K 182
           +  D+Y  +   S  L       +  QI+  + Y H  +V+HRDLKP N++      L K
Sbjct: 213 DGGDMYDYIMRHSGGLEEKLAKRYFRQIVEAISYCHKLHVVHRDLKPENVVFFEKPGLVK 392

Query: 183 ICDFGLA 189
           + DFG +
Sbjct: 393 LTDFGFS 413
>12672
          Length = 773

 Score = 37.4 bits (85), Expect = 0.010,   Method: Compositional matrix adjust.
 Identities = 23/90 (25%), Positives = 45/90 (50%), Gaps = 1/90 (1%)
 Frame = +3

Query: 154 GLKYIHSANVLHRDLKPSNLLINTTCDLKICDFGLARIA-DPEHDHTGFLTEYVATRWYR 212
           G++Y++    +HRD+K +N+L+++    K+ DF     A   E       +  + T  Y 
Sbjct: 27  GIQYLNDNGHVHRDIKTANILLDSEYTAKVGDFATVVSAPSGEGKTVQNASVVIGTAAYL 206

Query: 213 APEIMLNSKGYTKSIDIWSVGCILAEMLSN 242
           APE +      +  +D +S G +L E+++ 
Sbjct: 207 APEAI--HFDVSTKLDSYSFGVVLLEVITG 290
>21800
          Length = 855

 Score = 37.4 bits (85), Expect = 0.011,   Method: Compositional matrix adjust.
 Identities = 30/110 (27%), Positives = 56/110 (50%), Gaps = 14/110 (12%)
 Frame = +2

Query: 80  QTYCQRTLREIQILLRFRHENVIGIRDILRAPTLEAMRD----------VYIVQDLMETD 129
           Q Y +  L EI++L   R+ +     D  R  +++ + D          V +V +++  +
Sbjct: 416 QHYTETALDEIKLLKCVRNSDE---TDPAREKSVQLLDDFKISGVNGTHVCMVFEVLGYN 586

Query: 130 LYKLL---KSQQLSNDHICYFLYQILRGLKYIHS-ANVLHRDLKPSNLLI 175
           L KL+     Q +   ++   + Q+L GL Y+H+  N++H D+KP N+LI
Sbjct: 587 LLKLIIRSNYQGIPVHNVKLIIRQVLEGLNYLHAKCNIIHTDIKPENILI 736
>18481
          Length = 437

 Score = 37.0 bits (84), Expect = 0.013,   Method: Compositional matrix adjust.
 Identities = 20/44 (45%), Positives = 27/44 (61%), Gaps = 3/44 (6%)
 Frame = -1

Query: 150 QILRGLKYIHSANVLHRDLKPSNLLINTT--CD-LKICDFGLAR 190
           Q+L  L++IH    +HRDLKP N L+     C  L I DFGL++
Sbjct: 173 QLLSRLEFIHQKCFIHRDLKPDNFLMGLGRHCHRLYIIDFGLSK 42
>29360
          Length = 363

 Score = 36.2 bits (82), Expect = 0.021,   Method: Compositional matrix adjust.
 Identities = 29/110 (26%), Positives = 51/110 (46%), Gaps = 3/110 (2%)
 Frame = +3

Query: 69  VAIKKISPFEHQTYCQRTLREIQILLRFRHENVIGIRDILRAPTLEAMRDVYIVQDLMET 128
           VAIK +    H +Y ++   E+ IL R   E+      +      +      +V +++E 
Sbjct: 36  VAIKILK--NHPSYARQGQIEVSILQRLSQESADDYNFVRAFECFQHKNHTCLVFEMLEQ 209

Query: 129 DLYKLLKS---QQLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLI 175
           +LY  LK    Q L   +I     Q+L  L+ +    ++H DLKP N+++
Sbjct: 210 NLYDFLKQNKFQPLPLKYIRPITQQVLTALRKLKQLGLIHADLKPENIML 359
>16003
          Length = 926

 Score = 35.8 bits (81), Expect = 0.032,   Method: Compositional matrix adjust.
 Identities = 29/94 (30%), Positives = 47/94 (50%)
 Frame = -1

Query: 239 MLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINMKARNYLQSLPSKTKVAWAKLFP 298
           +L   P  PG   LDQL  I  +LG+P++ +   + ++   +Y+Q      K    ++F 
Sbjct: 926 LLIRLPFLPGDTDLDQLGKIFNMLGTPTETEWPAVTSLP--DYIQ-FKHCQKQPLKEIFT 756

Query: 299 KSDSKALDLLDRMLTFNPNKRITVEEALAHPYLE 332
            +    L+LLD++L  NP  R T  +AL  PY  
Sbjct: 755 AAGDDLLELLDKLLAMNPLHRCTATQALKMPYFS 654
>18663
          Length = 600

 Score = 35.0 bits (79), Expect = 0.047,   Method: Compositional matrix adjust.
 Identities = 18/44 (40%), Positives = 26/44 (59%)
 Frame = +2

Query: 203 TEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIF 246
           + +  T  Y APEI L  + Y  S+D W++G +L EML+ R  F
Sbjct: 2   STFCGTPNYIAPEI-LRGEDYGFSVDWWALGVLLYEMLAGRSPF 130
>35032
          Length = 465

 Score = 34.7 bits (78), Expect = 0.060,   Method: Compositional matrix adjust.
 Identities = 14/27 (51%), Positives = 21/27 (77%)
 Frame = +3

Query: 305 LDLLDRMLTFNPNKRITVEEALAHPYL 331
            DL+ R+L ++P+KR+T   ALAHP+L
Sbjct: 144 FDLVKRLLNYDPSKRLTPXXALAHPFL 224
>26009
          Length = 886

 Score = 34.7 bits (78), Expect = 0.064,   Method: Compositional matrix adjust.
 Identities = 13/31 (41%), Positives = 22/31 (70%)
 Frame = +3

Query: 147 FLYQILRGLKYIHSANVLHRDLKPSNLLINT 177
            + Q++  L ++HS  ++HRD+KP N+LI T
Sbjct: 726 VMKQLVSALDFMHSKQLVHRDIKPENVLILT 818
>20152
          Length = 445

 Score = 33.9 bits (76), Expect = 0.11,   Method: Compositional matrix adjust.
 Identities = 27/118 (22%), Positives = 46/118 (38%)
 Frame = +1

Query: 214 PEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCI 273
           PEI+L       ++D+WS+G IL  ++     F   +                 E L  I
Sbjct: 1   PEILLGDSYDAPAVDVWSLGVILYMLVVGEAPFQEAN---------------DSETLTMI 135

Query: 274 INMKARNYLQSLPSKTKVAWAKLFPKSDSKALDLLDRMLTFNPNKRITVEEALAHPYL 331
           ++ +                 ++ P    K  DL+++ML   P  R ++   LAHP+L
Sbjct: 136 MDCRY----------------QIPPHISHKCQDLIEKMLQREPVDRASLPHILAHPWL 261
>16350
          Length = 1108

 Score = 33.1 bits (74), Expect = 0.20,   Method: Compositional matrix adjust.
 Identities = 15/33 (45%), Positives = 22/33 (66%), Gaps = 1/33 (3%)
 Frame = +3

Query: 301 DSKAL-DLLDRMLTFNPNKRITVEEALAHPYLE 332
           D+KA  D L  ML F+P +R T  ++L HP+L+
Sbjct: 744 DAKAFADFLAPMLEFDPEQRATAAQSLQHPWLK 842
>36481
          Length = 806

 Score = 33.1 bits (74), Expect = 0.21,   Method: Compositional matrix adjust.
 Identities = 28/129 (21%), Positives = 55/129 (42%), Gaps = 4/129 (3%)
 Frame = +2

Query: 50  GEGAYGMVSSAYDHVRKTRVAIKKISPFEHQTYCQRTLREIQILLRFRHENVIGIRDILR 109
           GEG +G V    D ++   +A+K I   +   Y +    EI +L + R ++       ++
Sbjct: 389 GEGTFGKVVQCKDLLKGDDIALKIIKNVD--KYREAAKLEINVLEKLREKDPHAKHMCVQ 562

Query: 110 A-PTLEAMRDVYIVQDLMETDLYKLLKSQQLSN---DHICYFLYQILRGLKYIHSANVLH 165
                +    V I   ++   ++  LK         + + +  YQ+   + ++H   + H
Sbjct: 563 MLDWFDYHGHVCISFHMLGLSVFDFLKDNSYGAYPIEQVRHISYQLCYAVNFLHENQLTH 742

Query: 166 RDLKPSNLL 174
            DLKP N+L
Sbjct: 743 TDLKPENIL 769
>20513
          Length = 405

 Score = 33.1 bits (74), Expect = 0.22,   Method: Compositional matrix adjust.
 Identities = 15/34 (44%), Positives = 22/34 (64%), Gaps = 1/34 (2%)
 Frame = -1

Query: 300 SDSKAL-DLLDRMLTFNPNKRITVEEALAHPYLE 332
            D+KA  D L  ML F+P +R T  ++L HP+L+
Sbjct: 303 KDAKAFADFLAPMLEFDPEQRATAAQSLQHPWLK 202
>15931
          Length = 447

 Score = 32.0 bits (71), Expect = 0.42,   Method: Compositional matrix adjust.
 Identities = 10/32 (31%), Positives = 22/32 (68%)
 Frame = +1

Query: 305 LDLLDRMLTFNPNKRITVEEALAHPYLEQYYD 336
            DL+D+ML++  + R ++ +A+ HP+  + Y+
Sbjct: 76  FDLMDKMLSYEVSTRYSLRQAMRHPFFRKLYE 171
>17011
          Length = 1371

 Score = 32.0 bits (71), Expect = 0.44,   Method: Compositional matrix adjust.
 Identities = 13/26 (50%), Positives = 21/26 (80%)
 Frame = +1

Query: 306 DLLDRMLTFNPNKRITVEEALAHPYL 331
           DL+  ++TFNP+ R+T + AL+HP+L
Sbjct: 1   DLILDVVTFNPDHRLTPDLALSHPFL 78
>11529
          Length = 1062

 Score = 30.8 bits (68), Expect = 0.95,   Method: Compositional matrix adjust.
 Identities = 19/54 (35%), Positives = 28/54 (51%), Gaps = 2/54 (3%)
 Frame = -1

Query: 322  VEEALAHPYLEQYYDPTDEPVAEEPFTFDMELDDLPK--ERLKELIFQETARFQ 373
            V+EAL HPY+  +YD + E     P  +D  +D+     E  K LI+ E   F+
Sbjct: 1062 VDEALRHPYINVWYDES-EVNGPAPAPYDHSVDEREHSVEEWKSLIYDEVMEFE 904
>01377
          Length = 1058

 Score = 29.6 bits (65), Expect = 2.1,   Method: Compositional matrix adjust.
 Identities = 11/21 (52%), Positives = 17/21 (80%)
 Frame = -3

Query: 311  MLTFNPNKRITVEEALAHPYL 331
            ++TFNP+ R+T + AL HP+L
Sbjct: 1044 VVTFNPDHRLTPDLALCHPFL 982
>10464
          Length = 887

 Score = 29.3 bits (64), Expect = 2.8,   Method: Compositional matrix adjust.
 Identities = 14/39 (35%), Positives = 26/39 (66%)
 Frame = +1

Query: 128 TDLYKLLKSQQLSNDHICYFLYQILRGLKYIHSANVLHR 166
           T++  LLKS+Q+   ++C  LY I+R +K++ + N L +
Sbjct: 772 TNIISLLKSRQVIARYVC--LYLIVRKVKFLWTLNKLQK 882
>24241
          Length = 413

 Score = 28.9 bits (63), Expect = 4.1,   Method: Compositional matrix adjust.
 Identities = 19/66 (28%), Positives = 33/66 (50%), Gaps = 2/66 (3%)
 Frame = -2

Query: 45  QLQYIGEGAYGMVSSAYDHVRKTRVAIKKISPFEHQTYC-QRTLREIQILLRFRH-ENVI 102
           +L  IGEG YG+V          ++A+KKI     +       +REI +L   RH + ++
Sbjct: 331 RLSKIGEGTYGVVYKCRHRATGRKLAMKKIRLRGSEDGVPSSAIREIAMLRELRHTQXLV 152

Query: 103 GIRDIL 108
            + D++
Sbjct: 151 CLEDVI 134
>29472
          Length = 481

 Score = 28.1 bits (61), Expect = 5.9,   Method: Compositional matrix adjust.
 Identities = 15/41 (36%), Positives = 23/41 (56%)
 Frame = +2

Query: 249 KHYLDQLNHILGILGSPSQEDLNCIINMKARNYLQSLPSKT 289
           K  L +L+ +LGIL  P    L C ++ KAR++   +  KT
Sbjct: 299 KETLARLSDLLGILKYPCSLSLCCFLSSKARHHKNQMVIKT 421
>02980
          Length = 3325

 Score = 28.1 bits (61), Expect = 6.4,   Method: Compositional matrix adjust.
 Identities = 13/47 (27%), Positives = 27/47 (57%), Gaps = 5/47 (10%)
 Frame = -2

Query: 141  NDHICYF-----LYQILRGLKYIHSANVLHRDLKPSNLLINTTCDLK 182
            +D + YF     +++I   + Y+H +N  HRD++  +++   +C LK
Sbjct: 1701 HDQLFYFGVGEKVFRIFGFVFYVHPSNNHHRDIRLEHVMFVISCKLK 1561
>02357
          Length = 534

 Score = 28.1 bits (61), Expect = 6.6,   Method: Compositional matrix adjust.
 Identities = 10/21 (47%), Positives = 17/21 (80%)
 Frame = -3

Query: 311 MLTFNPNKRITVEEALAHPYL 331
           ++TF P++R+T + AL HP+L
Sbjct: 520 VVTFXPDQRLTPDLALCHPFL 458
>04799
          Length = 830

 Score = 27.3 bits (59), Expect = 9.6,   Method: Compositional matrix adjust.
 Identities = 15/68 (22%), Positives = 33/68 (48%), Gaps = 2/68 (2%)
 Frame = -1

Query: 55  GMVSSAYDHVRKTRVAIKKISPFEHQTYCQRTLREIQILLR--FRHENVIGIRDILRAPT 112
           GM+ +     R   ++++  S   +  +CQR  R++++L++  F  + + G   IL    
Sbjct: 698 GMIEAKITLNRLRHISVRVFSAIFYDRWCQRQRRDLRVLVQTHFHSQGLAGCHSIL*EEL 519

Query: 113 LEAMRDVY 120
           ++    VY
Sbjct: 518 IQCYGGVY 495
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31980806|ref|NP_058063.2| progesterone receptor
membrane component [Mus musculus]
         (195 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

05429                                                                 165   1e-41
31402                                                                  35   0.016
05106                                                                  27   4.1  
>05429
          Length = 830

 Score =  165 bits (417), Expect = 1e-41,   Method: Compositional matrix adjust.
 Identities = 88/168 (52%), Positives = 116/168 (69%), Gaps = 3/168 (1%)
 Frame = +3

Query: 21  LLHEIFTSPXXXXXXXXXXXXXYKIVRGDQPGASGDNDDDEP--PPLPRLKRRDFTPAEL 78
           L  E+FTSP             YKIV      +   ++  EP  P LP LK++DFT  +L
Sbjct: 21  LAVELFTSPLNLALLGMCGFLIYKIV-----ASRRRSEPSEPKEPELPPLKKQDFTLEQL 185

Query: 79  RRFDG-VQDPRILMAINGKVFDVTKGRKFYGPEGPYGVFAGRDASRGLATFCLDKEALKD 137
           R +DG  ++ RIL+A+NGKVFDVTKG++FYGP GPYG+F+GRDASR LATF L +++L+D
Sbjct: 186 REYDGKSKNGRILIAVNGKVFDVTKGKRFYGPGGPYGLFSGRDASRALATFSLSEDSLRD 365

Query: 138 EYDDLSDLTPAQQETLSDWDSQFTFKYHHVGKLLKEGEEPTVYSDDEE 185
           EYDDLSDL   Q E++ +W+ QFT KY +VGKLLK GE+P  Y+D E+
Sbjct: 366 EYDDLSDLNSMQMESVREWEMQFTEKYVYVGKLLKPGEQPADYTDTED 509
>31402
          Length = 1272

 Score = 35.4 bits (80), Expect = 0.016,   Method: Compositional matrix adjust.
 Identities = 20/55 (36%), Positives = 30/55 (54%)
 Frame = +2

Query: 117 AGRDASRGLATFCLDKEALKDEYDDLSDLTPAQQETLSDWDSQFTFKYHHVGKLL 171
           AGRD SR   T    ++ L D   D+S  T ++   L +WDS +   Y +VGK++
Sbjct: 2   AGRDGSRAFVTGDFTEKGLTD---DVSGFTASEALGLEEWDSFYKRDYTYVGKVV 157
>05106
          Length = 482

 Score = 27.3 bits (59), Expect = 4.1,   Method: Compositional matrix adjust.
 Identities = 9/27 (33%), Positives = 16/27 (59%)
 Frame = -2

Query: 156 WDSQFTFKYHHVGKLLKEGEEPTVYSD 182
           W  +  + Y HVGK++K G +  V+ +
Sbjct: 217 WKYKIIYHYAHVGKIVKTGTQAHVHGN 137
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|40807498|ref|NP_032313.2| heat-responsive protein 12
[Mus musculus]
         (135 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

00505                                                                 164   1e-41
07915                                                                  56   5e-09
19535                                                                  27   1.8  
23693                                                                  25   6.5  
>00505
          Length = 1436

 Score =  164 bits (414), Expect = 1e-41,   Method: Compositional matrix adjust.
 Identities = 77/122 (63%), Positives = 98/122 (80%)
 Frame = +3

Query: 9   ISTTKAPAAIGPYSQAVQVDRTIYISGQVGLDPSSGQLVPGGVVEEAKQALKNLGEILKA 68
           IST KAPAA+GPYSQAV  + T+Y+SG +G  P + ++V GG   E +QALKN+GE+LKA
Sbjct: 3   ISTAKAPAAVGPYSQAVVANNTMYMSGMIGFLPETMEIVQGGAGPETEQALKNMGEVLKA 182

Query: 69  AGCDFNNVVKTTVLLADMNDFGTVNEIYKTYFQGSLPARAAYQVAALPRGSRVEIEAIAV 128
           +G  FNN+VKTTVLLAD+ND+ TVN++Y  YF    PARAAYQVAALP+G++VEIEAIA+
Sbjct: 183 SGAAFNNIVKTTVLLADINDYATVNQVYAKYFTEKQPARAAYQVAALPKGAKVEIEAIAI 362

Query: 129 QG 130
            G
Sbjct: 363 LG 368
>07915
          Length = 1385

 Score = 55.8 bits (133), Expect = 5e-09,   Method: Compositional matrix adjust.
 Identities = 26/55 (47%), Positives = 37/55 (67%)
 Frame = +3

Query: 14  APAAIGPYSQAVQVDRTIYISGQVGLDPSSGQLVPGGVVEEAKQALKNLGEILKA 68
           APA IGPYSQA  V + ++I+GQ+ L P + QLV GG V + + AL++   + KA
Sbjct: 81  APANIGPYSQATVVGKQVHIAGQIALMPGTMQLVTGGCVVQCRLALQHANSVFKA 245
>19535
          Length = 966

 Score = 27.3 bits (59), Expect = 1.8,   Method: Compositional matrix adjust.
 Identities = 19/61 (31%), Positives = 27/61 (44%)
 Frame = -3

Query: 50  GVVEEAKQALKNLGEILKAAGCDFNNVVKTTVLLADMNDFGTVNEIYKTYFQGSLPARAA 109
           G   E KQA+KN  + LK  G          +LL D  ++  + E       GS PA++ 
Sbjct: 475 GDQREHKQAIKNFEKCLKPGG----------ILLIDHRNYDNILET------GSTPAKSI 344

Query: 110 Y 110
           Y
Sbjct: 343 Y 341
>23693
          Length = 1305

 Score = 25.4 bits (54), Expect = 6.5,   Method: Compositional matrix adjust.
 Identities = 14/42 (33%), Positives = 22/42 (52%)
 Frame = +2

Query: 25  VQVDRTIYISGQVGLDPSSGQLVPGGVVEEAKQALKNLGEIL 66
           V+VD  + + G V    ++   VPGGVV   +  L   G++L
Sbjct: 869 VEVDEVLCLVGHVTAKVATHDAVPGGVVLLVELFLDEGGDVL 994
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|108860695|ref|NP_031650.3| chromobox homolog 3 [Mus
musculus]
         (183 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

07241                                                                 122   2e-41
19326                                                                  61   2e-10
02319                                                                  39   0.001
12789                                                                  28   3.2  
>07241
          Length = 2218

 Score =  122 bits (306), Expect(2) = 2e-41,   Method: Compositional matrix adjust.
 Identities = 56/63 (88%), Positives = 60/63 (95%)
 Frame = +2

Query: 114 PRGFARGLDPERIIGATDSSGELMFLMKWKDSDEADLVLAKEANMKCPQIVIAFYEERLT 173
           PRGF RGL PERIIGATDSSGELMFLMKWKDSDEADLV A++AN+KCPQIVIAFYEERLT
Sbjct: 419 PRGFDRGLQPERIIGATDSSGELMFLMKWKDSDEADLVPARQANIKCPQIVIAFYEERLT 598

Query: 174 WHS 176
           WH+
Sbjct: 599 WHT 607

 Score = 63.2 bits (152), Expect(2) = 2e-41,   Method: Compositional matrix adjust.
 Identities = 26/46 (56%), Positives = 35/46 (76%)
 Frame = +3

Query: 36  LDRRVVNGKVEYFLKWKGFTDADNTWEPEENLDCPELIEAFLNSQK 81
           +D R+  GK EY LKWKG+ +++NTWEP ENLDCP+LI  F + +K
Sbjct: 168 VDSRMKAGKKEYLLKWKGYPNSENTWEPSENLDCPDLIAEFEDYKK 305

 Score = 29.6 bits (65), Expect = 0.66,   Method: Compositional matrix adjust.
 Identities = 11/35 (31%), Positives = 22/35 (62%)
 Frame = +2

Query: 42  NGKVEYFLKWKGFTDADNTWEPEENLDCPELIEAF 76
           +G++ + +KWK   +AD     + N+ CP+++ AF
Sbjct: 476 SGELMFLMKWKDSDEADLVPARQANIKCPQIVIAF 580

 Score = 28.1 bits (61), Expect = 2.1,   Method: Compositional matrix adjust.
 Identities = 10/44 (22%), Positives = 23/44 (52%)
 Frame = +3

Query: 124 ERIIGATDSSGELMFLMKWKDSDEADLVLAKEANMKCPQIVIAF 167
           E+++ +   +G+  +L+KWK    ++       N+ CP ++  F
Sbjct: 159 EKVVDSRMKAGKKEYLLKWKGYPNSENTWEPSENLDCPDLIAEF 290
>19326
          Length = 401

 Score = 61.2 bits (147), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 26/44 (59%), Positives = 34/44 (77%)
 Frame = +1

Query: 36  LDRRVVNGKVEYFLKWKGFTDADNTWEPEENLDCPELIEAFLNS 79
           +D R+  GK EY LKWKG+ +++NTWEP ENLDCP+LI  F +S
Sbjct: 268 VDSRMKAGKKEYLLKWKGYPNSENTWEPSENLDCPDLIAEFEDS 399

 Score = 28.5 bits (62), Expect = 1.8,   Method: Compositional matrix adjust.
 Identities = 10/44 (22%), Positives = 23/44 (52%)
 Frame = +1

Query: 124 ERIIGATDSSGELMFLMKWKDSDEADLVLAKEANMKCPQIVIAF 167
           E+++ +   +G+  +L+KWK    ++       N+ CP ++  F
Sbjct: 259 EKVVDSRMKAGKKEYLLKWKGYPNSENTWEPSENLDCPDLIAEF 390
>02319
          Length = 1312

 Score = 39.3 bits (90), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 17/43 (39%), Positives = 25/43 (58%), Gaps = 1/43 (2%)
 Frame = +1

Query: 36  LDRRVVNGKVEYFLKWKGFTDADNTWEPEENL-DCPELIEAFL 77
           L++R   G VEY ++W+GF D  ++WEP   +  C   I  FL
Sbjct: 100 LEQRKRKGVVEYLVRWQGFNDLYDSWEPASGIAHCKNAITNFL 228
>12789
          Length = 2095

 Score = 27.7 bits (60), Expect = 3.2,   Method: Compositional matrix adjust.
 Identities = 12/29 (41%), Positives = 19/29 (65%)
 Frame = -1

Query: 45  VEYFLKWKGFTDADNTWEPEENLDCPELI 73
           +EYF+ WK  TD  +  + E ++ CPEL+
Sbjct: 250 MEYFIVWKNSTDMISAAD-EHDVGCPELL 167
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|40789286|ref|NP_659507.2| huntingtin interacting
protein 1 related [Mus musculus]
         (1068 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

30501                                                                 167   2e-41
09133                                                                  67   6e-11
28758                                                                  32   1.2  
36841                                                                  31   2.5  
07138                                                                  31   3.2  
>30501
          Length = 638

 Score =  167 bits (422), Expect = 2e-41,   Method: Compositional matrix adjust.
 Identities = 93/216 (43%), Positives = 136/216 (62%), Gaps = 1/216 (0%)
 Frame = -1

Query: 757 LQGILQLGQDLKPKSLDVRQEELGAMVDKEMAATSAAIEDAVRRIEDMMSQARHESSGVK 816
           L  ++QL  +   KS+D        +++KE+     AIE+A  +I +++S++R   + +K
Sbjct: 635 LNALVQLILNNFEKSVD-----FDKLIEKELKEMDVAIEEAASKIINLLSKSRENDNKIK 471

Query: 817 LEVNERILNSCTDLMKAIRLLVMTSTSLQKEIVESGRGAATQQEFYAKNSRWTEGLISAS 876
           LEVNE+IL +CT LM+ I++L++ S +LQKEIV S +G A+  EFY +NS+W++GLISAS
Sbjct: 470 LEVNEKILEACTSLMECIKILILKSRALQKEIVSSQKGNASANEFYKRNSQWSDGLISAS 291

Query: 877 KAVGWGATQLVESADKVVLHMGKYE-ELIVCSHEIAASTAQLVAASKVKANKNSPHLSRL 935
           K+V   A  LVE+A+  V        ELIV + EIAA T QLV ASKVKAN+NS +L+ L
Sbjct: 290 KSVAKAANYLVEAANNAVNSDSXQNFELIVAAQEIAACTVQLVIASKVKANRNSENLTNL 111

Query: 936 QECSRTVNERAAYVVASTKSGQEQIEDRDTMDFSGL 971
              SR V +    VVA+ K G  + E +  +D   L
Sbjct: 110 TAASRNVTKATGVVVATVKDGNSRQEQQQDIDLCKL 3
>09133
          Length = 1844

 Score = 66.6 bits (161), Expect = 6e-11,   Method: Compositional matrix adjust.
 Identities = 43/127 (33%), Positives = 73/127 (57%), Gaps = 1/127 (0%)
 Frame = +1

Query: 817  LEVNERILNSCTDLMKAIRLLVMTSTSLQKEIVESGRGAAT-QQEFYAKNSRWTEGLISA 875
            L  +E+IL +   +  A   LV ++++ Q+E+V  G+ ++T  +    ++ +W++GLISA
Sbjct: 1006 LNFDEQILEAAKSIAAATAALVKSASAAQRELVAQGKVSSTFTRHAVDEDGQWSQGLISA 1185

Query: 876  SKAVGWGATQLVESADKVVLHMGKYEELIVCSHEIAASTAQLVAASKVKANKNSPHLSRL 935
            ++ V      L E+A+ +V      E+LI  + E+A STAQL+ A KVKA+  S  + RL
Sbjct: 1186 ARMVAAATHSLCEAANAMVQGHASEEKLIASAKEVAGSTAQLLMACKVKADPGSVAMQRL 1365

Query: 936  QECSRTV 942
            Q     V
Sbjct: 1366 QAAGNAV 1386
>28758
          Length = 647

 Score = 32.0 bits (71), Expect = 1.2,   Method: Composition-based stats.
 Identities = 15/35 (42%), Positives = 18/35 (51%)
 Frame = +2

Query: 207 SSGQCRLAPLIQVIQDCSHLYHYTVKLMFKLHSCL 241
           S GQC   PL Q +QDCSH        ++  H CL
Sbjct: 242 SYGQCDECPLHQTLQDCSH-------CLYDAHQCL 325
>36841
          Length = 203

 Score = 31.2 bits (69), Expect = 2.5,   Method: Composition-based stats.
 Identities = 18/60 (30%), Positives = 29/60 (48%)
 Frame = +1

Query: 98  HPNVLHDYQRYRSNIREIGDLWGHLRDQYGHLVNIYTKLLLTKISFHLKHPQFPAGLEVT 157
           HPNVLH   + R   R+   +W +LR    H  +  T+L  T  S  + +   P+ L ++
Sbjct: 22  HPNVLHV*NKCRKQSRDCQQIWLYLRSSRNHKPS*ETELFETHYSLVIFNRPCPSPLSLS 201
>07138
          Length = 567

 Score = 30.8 bits (68), Expect = 3.2,   Method: Composition-based stats.
 Identities = 11/22 (50%), Positives = 13/22 (59%)
 Frame = +2

Query: 87  CHVLHKVLRDGHPNVLHDYQRY 108
           CH LHK  +  H N LH Y R+
Sbjct: 395 CHFLHKS*KTSHDNYLHKYNRF 460
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6680922|ref|NP_031710.1| centrin 3 [Mus musculus]
         (167 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

22063                                                                 111   2e-41
14945                                                                 114   2e-26
14594                                                                 107   2e-24
26610                                                                  76   6e-15
14366                                                                  72   8e-14
06641                                                                  67   3e-12
05237                                                                  67   4e-12
18171                                                                  65   2e-11
01019                                                                  59   1e-09
17484                                                                  53   5e-08
20251                                                                  52   1e-07
38338                                                                  51   3e-07
32088                                                                  47   4e-06
16255                                                                  44   3e-05
03732                                                                  40   4e-04
07385                                                                  39   7e-04
04697                                                                  39   0.001
11425                                                                  39   0.001
04643                                                                  37   0.004
27864                                                                  37   0.004
26849                                                                  36   0.007
03616                                                                  35   0.018
17977                                                                  34   0.028
00167                                                                  34   0.033
19942                                                                  34   0.035
19912                                                                  34   0.036
28617                                                                  33   0.047
22273                                                                  33   0.071
26019                                                                  31   0.27 
01773                                                                  30   0.34 
15966                                                                  30   0.47 
05230                                                                  30   0.67 
07678                                                                  29   0.95 
35350                                                                  28   2.0  
21620                                                                  28   2.0  
16109                                                                  27   3.3  
33397                                                                  27   5.6  
32153                                                                  26   6.7  
08380                                                                  26   7.5  
>22063
          Length = 688

 Score =  111 bits (278), Expect(2) = 2e-41,   Method: Compositional matrix adjust.
 Identities = 57/105 (54%), Positives = 77/105 (73%)
 Frame = +3

Query: 13  KTKRKKRRELSEEQKQEIKDAFELFDTDKDQAIDYHELKVAMRALGFDVKKADVLKILKD 72
           + K   + EL+EEQKQEI++AF+LFD D    ID  ELKVAMRALGF+ KK ++ K++ +
Sbjct: 126 RKKTGPKCELTEEQKQEIREAFDLFDADGSGTIDAKELKVAMRALGFEPKKEEIKKMIAE 305

Query: 73  YDREATGKITFEDFNEVVTDWILERDPHEEILKAFKLFDDDDSGK 117
            D+E TG I F DF  ++T  + E+D  EEILKAF+LFDDD++GK
Sbjct: 306 IDKEGTGTIDFNDFLTIMTQKMSEKDAKEEILKAFRLFDDDETGK 440

 Score = 73.6 bits (179), Expect(2) = 2e-41,   Method: Compositional matrix adjust.
 Identities = 35/48 (72%), Positives = 43/48 (89%)
 Frame = +1

Query: 116 GKISLRNLRRVARELGENMSDEELRAMIEEFDKDGDGEINQEEFIAIM 163
            KIS RNL+RVA+ELGEN++DEEL+ MI+E D+DGDGEINQEEF+ IM
Sbjct: 436 AKISFRNLKRVAKELGENLTDEELQEMIDEADRDGDGEINQEEFLRIM 579

 Score = 53.5 bits (127), Expect = 4e-08,   Method: Compositional matrix adjust.
 Identities = 29/64 (45%), Positives = 39/64 (60%)
 Frame = +3

Query: 101 EEILKAFKLFDDDDSGKISLRNLRRVARELGENMSDEELRAMIEEFDKDGDGEINQEEFI 160
           +EI +AF LFD D SG I  + L+   R LG     EE++ MI E DK+G G I+  +F+
Sbjct: 171 QEIREAFDLFDADGSGTIDAKELKVAMRALGFEPKKEEIKKMIAEIDKEGTGTIDFNDFL 350

Query: 161 AIMT 164
            IMT
Sbjct: 351 TIMT 362
>14945
          Length = 1337

 Score =  114 bits (285), Expect = 2e-26,   Method: Compositional matrix adjust.
 Identities = 60/117 (51%), Positives = 80/117 (68%)
 Frame = +1

Query: 15  KRKKRRELSEEQKQEIKDAFELFDTDKDQAIDYHELKVAMRALGFDVKKADVLKILKDYD 74
           K   + EL+EEQKQEI++AF+LFD D    ID  ELKVAMRALGF+ KK ++ K++ + D
Sbjct: 73  KTGPKCELTEEQKQEIREAFDLFDADGSGTIDAKELKVAMRALGFEPKKEEIKKMIAEID 252

Query: 75  REATGKITFEDFNEVVTDWILERDPHEEILKAFKLFDDDDSGKISLRNLRRVARELG 131
           +E TG I F DF  ++T  + E+D  EEILKAF+LFDDD++GK  L  L    +  G
Sbjct: 253 KEGTGTIDFNDFLTIMTQKMSEKDAKEEILKAFRLFDDDETGKNLLPQLETGGQGAG 423

 Score = 73.9 bits (180), Expect = 3e-14,   Method: Compositional matrix adjust.
 Identities = 35/49 (71%), Positives = 43/49 (87%)
 Frame = +2

Query: 115 SGKISLRNLRRVARELGENMSDEELRAMIEEFDKDGDGEINQEEFIAIM 163
             KIS RNL+RVA+ELGEN++DEEL+ MI+E D+DGDGEINQEEF+ IM
Sbjct: 374 PAKISFRNLKRVAKELGENLTDEELQEMIDEADRDGDGEINQEEFLRIM 520

 Score = 53.9 bits (128), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 30/70 (42%), Positives = 41/70 (58%)
 Frame = +1

Query: 95  LERDPHEEILKAFKLFDDDDSGKISLRNLRRVARELGENMSDEELRAMIEEFDKDGDGEI 154
           L  +  +EI +AF LFD D SG I  + L+   R LG     EE++ MI E DK+G G I
Sbjct: 94  LTEEQKQEIREAFDLFDADGSGTIDAKELKVAMRALGFEPKKEEIKKMIAEIDKEGTGTI 273

Query: 155 NQEEFIAIMT 164
           +  +F+ IMT
Sbjct: 274 DFNDFLTIMT 303
>14594
          Length = 1014

 Score =  107 bits (268), Expect = 2e-24,   Method: Compositional matrix adjust.
 Identities = 59/144 (40%), Positives = 88/144 (61%)
 Frame = +3

Query: 22  LSEEQKQEIKDAFELFDTDKDQAIDYHELKVAMRALGFDVKKADVLKILKDYDREATGKI 81
           L++EQ  E K+AF LFD D D  I   EL   MR+LG +  + ++  ++ + D +  G I
Sbjct: 423 LTDEQVAEFKEAFSLFDKDGDGTITTSELGTVMRSLGQNPTENELQDMINEVDADGNGTI 602

Query: 82  TFEDFNEVVTDWILERDPHEEILKAFKLFDDDDSGKISLRNLRRVARELGENMSDEELRA 141
            FE+F  ++   + + D  EE+ +AF++FD D +G IS   LR V   LGE ++DEE+  
Sbjct: 603 DFEEFLHMMARKMKDTDCEEELREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDE 782

Query: 142 MIEEFDKDGDGEINQEEFIAIMTG 165
           MI+E D DGDG +N EEF+ +MT 
Sbjct: 783 MIKEADLDGDGMVNYEEFVTMMTA 854
>26610
          Length = 455

 Score = 76.3 bits (186), Expect = 6e-15,   Method: Compositional matrix adjust.
 Identities = 45/148 (30%), Positives = 81/148 (54%), Gaps = 2/148 (1%)
 Frame = +3

Query: 19  RRELSE--EQKQEIKDAFELFDTDKDQAIDYHELKVAMRALGFDVKKADVLKILKDYDRE 76
           R  LS     K  + +AFELFDTD D  I   E+  A+R+LG  V  +D+ ++L     E
Sbjct: 9   RSSLSPTMSSKDAVSEAFELFDTDNDGKIAASEVGTAIRSLGHVVTDSDLRRLLSKAGIE 188

Query: 77  ATGKITFEDFNEVVTDWILERDPHEEILKAFKLFDDDDSGKISLRNLRRVARELGENMSD 136
             GK+    F ++V   +   +  +++ +AF   D + SG +    LR +   +G+ ++D
Sbjct: 189 PHGKVDMNRFRQLV-QPLQGVNYTKQLDEAFNTIDKEGSGFVMATELRHLLTHMGDRITD 365

Query: 137 EELRAMIEEFDKDGDGEINQEEFIAIMT 164
           EE  A++EE + D +G + ++EF+ +++
Sbjct: 366 EEFNALLEELEVDSNGRVRRKEFVQLLS 449
>14366
          Length = 499

 Score = 72.4 bits (176), Expect = 8e-14,   Method: Compositional matrix adjust.
 Identities = 36/138 (26%), Positives = 79/138 (57%)
 Frame = -3

Query: 26  QKQEIKDAFELFDTDKDQAIDYHELKVAMRALGFDVKKADVLKILKDYDREATGKITFED 85
           +++E+++AF + +   D  I  ++L + +R++G    ++ +  +  +++      +T ++
Sbjct: 473 RQEELQEAF-IMNCSPDNTIALNKLGIVVRSIGRAPTESQLKTLTMEFENRGKRTLTLQE 297

Query: 86  FNEVVTDWILERDPHEEILKAFKLFDDDDSGKISLRNLRRVARELGENMSDEELRAMIEE 145
              +VT +    +  + + +AF++FD + +G I+   LR V   LGE +SDEE+  MI E
Sbjct: 296 VIAIVTKYEFAPETSDNLREAFRIFDKEGNGMINAAELRHVLTHLGEKLSDEEVDEMIRE 117

Query: 146 FDKDGDGEINQEEFIAIM 163
            D  GDG+++  +F+ +M
Sbjct: 116 ADISGDGQVSYNDFVKVM 63

 Score = 33.1 bits (74), Expect = 0.057,   Method: Compositional matrix adjust.
 Identities = 20/65 (30%), Positives = 35/65 (53%)
 Frame = -3

Query: 100 HEEILKAFKLFDDDDSGKISLRNLRRVARELGENMSDEELRAMIEEFDKDGDGEINQEEF 159
            EE+ +AF +    D+  I+L  L  V R +G   ++ +L+ +  EF+  G   +  +E 
Sbjct: 470 QEELQEAFIMNCSPDN-TIALNKLGIVVRSIGRAPTESQLKTLTMEFENRGKRTLTLQEV 294

Query: 160 IAIMT 164
           IAI+T
Sbjct: 293 IAIVT 279
>06641
          Length = 726

 Score = 67.0 bits (162), Expect = 3e-12,   Method: Compositional matrix adjust.
 Identities = 41/145 (28%), Positives = 80/145 (55%), Gaps = 5/145 (3%)
 Frame = +1

Query: 27  KQEIKDAFELFDTDKDQAIDYHELKVAMRALGFDVKKADVLKILKDYDRE-ATGKITFED 85
           +++I DAF++FD + ++ +D  E+   +R+LG    +A++  +L + + E  TG I FE 
Sbjct: 190 QKKITDAFDIFDHEANKTVDVREVGTIIRSLGCCPSEAELHDMLAEIEEEEPTGYIRFEK 369

Query: 86  FNEVVTDWILERD----PHEEILKAFKLFDDDDSGKISLRNLRRVARELGENMSDEELRA 141
           F  ++T  ++ER     P ++I+KAF++ D +  G +    L +   E GE  + EEL  
Sbjct: 370 FLPMMTKVLMERRYKAVPEDQIVKAFQVLDVEGRGYLLQEELSKYMTEEGEPFTSEELEE 549

Query: 142 MIEEFDKDGDGEINQEEFIAIMTGD 166
           M+ +      G I  +++ ++M  +
Sbjct: 550 MMSQALDPEKGYIPYKDYASLMAAE 624
>05237
          Length = 472

 Score = 66.6 bits (161), Expect = 4e-12,   Method: Compositional matrix adjust.
 Identities = 34/69 (49%), Positives = 47/69 (68%)
 Frame = +3

Query: 96  ERDPHEEILKAFKLFDDDDSGKISLRNLRRVARELGENMSDEELRAMIEEFDKDGDGEIN 155
           E D  +E+ +AF++FD D +G IS   LR V   LGE ++DEE+  MI E D DGDG++N
Sbjct: 12  ETDTDDELREAFRVFDKDGNGFISASELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVN 191

Query: 156 QEEFIAIMT 164
            EEF+ +MT
Sbjct: 192 YEEFVKMMT 218
>18171
          Length = 1131

 Score = 64.7 bits (156), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 35/99 (35%), Positives = 57/99 (57%), Gaps = 3/99 (3%)
 Frame = +3

Query: 68  KILKDYDREATGKITFEDFNEVVTDWILERDPHEE---ILKAFKLFDDDDSGKISLRNLR 124
           K++ D      GK+ F DF  ++   +  +DP EE   +L+A  L D D +G IS   LR
Sbjct: 57  KLIHDVSNSNQGKVDFPDFLTLMARTVGSKDPQEEDDAMLEALTLLDKDQTGVISTALLR 236

Query: 125 RVARELGENMSDEELRAMIEEFDKDGDGEINQEEFIAIM 163
            V   LG+ ++ EE+  +I+E DK+  G+++ +EFI +M
Sbjct: 237 HVLTTLGDQLTSEEVEELIKEADKEETGQVDYKEFIKMM 353
>01019
          Length = 1705

 Score = 58.5 bits (140), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 29/56 (51%), Positives = 38/56 (67%)
 Frame = +1

Query: 109 LFDDDDSGKISLRNLRRVARELGENMSDEELRAMIEEFDKDGDGEINQEEFIAIMT 164
           +FD D +G IS   LR V   LGE ++DEE+  MI E D DGDG++N EEF+ +MT
Sbjct: 43  VFDKDGNGFISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVTMMT 210
>17484
          Length = 471

 Score = 53.1 bits (126), Expect = 5e-08,   Method: Compositional matrix adjust.
 Identities = 25/65 (38%), Positives = 42/65 (64%)
 Frame = -3

Query: 101 EEILKAFKLFDDDDSGKISLRNLRRVARELGENMSDEELRAMIEEFDKDGDGEINQEEFI 160
           +E+  AF+ FD +  G IS+  LR+   ++G+ +SD ++ ++I + DKDGDG +N EEF 
Sbjct: 271 KEMRDAFRAFDQNGDGVISISELRQAMAKMGQKLSDADVESIIRDVDKDGDGFVNYEEFT 92

Query: 161 AIMTG 165
             + G
Sbjct: 91  KFIAG 77

 Score = 49.3 bits (116), Expect = 8e-07,   Method: Compositional matrix adjust.
 Identities = 27/89 (30%), Positives = 49/89 (55%), Gaps = 5/89 (5%)
 Frame = -3

Query: 19  RRELSEEQKQEIKDAFELFDTDKDQAIDYHELKVAMRALGFDVKKADVLKILKDYDREAT 78
           R +   E+ +E++DAF  FD + D  I   EL+ AM  +G  +  ADV  I++D D++  
Sbjct: 298 RMKGGSEKDKEMRDAFRAFDQNGDGVISISELRQAMAKMGQKLSDADVESIIRDVDKDGD 119

Query: 79  GKITFEDFNEVV-----TDWILERDPHEE 102
           G + +E+F + +     T ++  R+ + E
Sbjct: 118 GFVNYEEFTKFIAGQQ*TMFLPSRESYNE 32

 Score = 26.6 bits (57), Expect(2) = 0.040,   Method: Compositional matrix adjust.
 Identities = 19/52 (36%), Positives = 27/52 (51%), Gaps = 2/52 (3%)
 Frame = -1

Query: 73  YDREATGKITFEDFNEVV--TDWILERDPHEEILKAFKLFDDDDSGKISLRN 122
           YD++  GKIT  +F  VV      L     EE+++A    D D SG I L++
Sbjct: 465 YDQDGNGKITRNEFRSVVRMLGHSLSEKELEEMMQA---ADTDASGAIELKS 319

 Score = 25.8 bits (55), Expect(2) = 0.040,   Method: Compositional matrix adjust.
 Identities = 14/39 (35%), Positives = 20/39 (51%)
 Frame = -3

Query: 126 VARELGENMSDEELRAMIEEFDKDGDGEINQEEFIAIMT 164
           V R  G +  D+E+R     FD++GDG I+  E    M 
Sbjct: 304 VGRMKGGSEKDKEMRDAFRAFDQNGDGVISISELRQAMA 188
>20251
          Length = 2203

 Score = 52.0 bits (123), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 35/120 (29%), Positives = 59/120 (49%)
 Frame = +3

Query: 24  EEQKQEIKDAFELFDTDKDQAIDYHELKVAMRALGFDVKKADVLKILKDYDREATGKITF 83
           + Q QE K+AF + D ++D  ID  +L   + +LG +  +  + +++      A G I F
Sbjct: 147 QSQIQEFKEAFNMIDQNRDGFIDKEDLGDMLASLGKNPTEGQLDEMMN----XAPGPINF 314

Query: 84  EDFNEVVTDWILERDPHEEILKAFKLFDDDDSGKISLRNLRRVARELGENMSDEELRAMI 143
             F  +  D +   DP + I  AF  FD+D  G I    LR +   +G+  +D+E+  M 
Sbjct: 315 TMFLTMFGDKLNGTDPEDVIKNAFACFDEDGKGVIQEDRLRELLTTMGDRFTDDEVDEMF 494
>38338
          Length = 463

 Score = 50.8 bits (120), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 25/53 (47%), Positives = 33/53 (62%)
 Frame = -2

Query: 102 EILKAFKLFDDDDSGKISLRNLRRVARELGENMSDEELRAMIEEFDKDGDGEI 154
           E  +AF LFD D  G I+ + L  V R LG+N ++ EL+ MI E D DG+G I
Sbjct: 165 EFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTI 7

 Score = 49.7 bits (117), Expect = 5e-07,   Method: Compositional matrix adjust.
 Identities = 29/77 (37%), Positives = 42/77 (54%), Gaps = 2/77 (2%)
 Frame = -2

Query: 9   LVVDKTKRKKRR--ELSEEQKQEIKDAFELFDTDKDQAIDYHELKVAMRALGFDVKKADV 66
           LV  +T  K     +L+EEQ  E K+AF LFD D D  I   EL   MR+LG +  +A++
Sbjct: 231 LVHHQTHSKSNMADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAEL 52

Query: 67  LKILKDYDREATGKITF 83
             ++ + D +  G I F
Sbjct: 51  QDMINEVDADGNGTIDF 1
>32088
          Length = 1928

 Score = 47.0 bits (110), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 24/65 (36%), Positives = 36/65 (55%)
 Frame = +1

Query: 95  LERDPHEEILKAFKLFDDDDSGKISLRNLRRVARELGENMSDEELRAMIEEFDKDGDGEI 154
           L+ D   E+   F   DDD++G IS   L    R +G N+   ELR ++ ++D  GDG +
Sbjct: 925 LDEDQLTELRSVFDSIDDDNNGHISXGELDSAFRAVGLNIPGYELRTIMSKYDASGDGRL 1104

Query: 155 NQEEF 159
           N +EF
Sbjct: 1105NMDEF 1119
>16255
          Length = 767

 Score = 43.9 bits (102), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 20/35 (57%), Positives = 27/35 (77%)
 Frame = -2

Query: 130 LGENMSDEELRAMIEEFDKDGDGEINQEEFIAIMT 164
           LGE ++DEE+  MI E D DGDG++N EEF+ +MT
Sbjct: 757 LGEKLTDEEVDEMIREADIDGDGQVNYEEFVTMMT 653
>03732
          Length = 1114

 Score = 40.0 bits (92), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 23/90 (25%), Positives = 44/90 (48%)
 Frame = -1

Query: 31  KDAFELFDTDKDQAIDYHELKVAMRALGFDVKKADVLKILKDYDREATGKITFEDFNEVV 90
           ++ F  +D D   +ID +ELK A+   G+ +       ++K +DR+  G + F+DF +  
Sbjct: 892 QNCFRSYDRDNSGSIDRNELKNALTGFGYRLSDRFFDVLVKKFDRQGKGTVAFDDFIQCC 713

Query: 91  TDWILERDPHEEILKAFKLFDDDDSGKISL 120
              +L     + +  +F+  D D  G I +
Sbjct: 712 V--VL-----QTLTTSFRTHDQDQDGWIQI 644

 Score = 36.6 bits (83), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 21/58 (36%), Positives = 32/58 (55%), Gaps = 1/58 (1%)
 Frame = -1

Query: 107  FKLFDDDDSGKISLRNLRR-VARELGENMSDEELRAMIEEFDKDGDGEINQEEFIAIM 163
            F+  D D SG IS+  L++ ++       + E +R MI  FD+D  G IN +EF A+ 
Sbjct: 1084 FQRIDKDRSGNISVNELQQALSNGTWTPFNPETVRLMIGMFDRDNSGTINFQEFQALW 911

 Score = 31.2 bits (69), Expect = 0.23,   Method: Compositional matrix adjust.
 Identities = 18/97 (18%), Positives = 44/97 (45%)
 Frame = -1

Query: 69   ILKDYDREATGKITFEDFNEVVTDWILERDPHEEILKAFKLFDDDDSGKISLRNLRRVAR 128
            I +  D++ +G I+  +  + +++        E +     +FD D+SG I+ +  + + +
Sbjct: 1087 IFQRIDKDRSGNISVNELQQALSNGTWTPFNPETVRLMIGMFDRDNSGTINFQEFQALWK 908

Query: 129  ELGENMSDEELRAMIEEFDKDGDGEINQEEFIAIMTG 165
             +       + +     +D+D  G I++ E    +TG
Sbjct: 907  YV------TDWQNCFRSYDRDNSGSIDRNELKNALTG 815
>07385
          Length = 1292

 Score = 39.3 bits (90), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 17/33 (51%), Positives = 25/33 (75%)
 Frame = +3

Query: 132 ENMSDEELRAMIEEFDKDGDGEINQEEFIAIMT 164
           + ++DEE+  MI E D DGDG++N EEF+ +MT
Sbjct: 147 QKLTDEEVDEMIREADIDGDGQVNYEEFVKMMT 245
>04697
          Length = 559

 Score = 38.5 bits (88), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 17/69 (24%), Positives = 41/69 (59%)
 Frame = +1

Query: 97  RDPHEEILKAFKLFDDDDSGKISLRNLRRVARELGENMSDEELRAMIEEFDKDGDGEINQ 156
           +D   + +K FK  D  + G +++ +LRR  +++GE +++++L  ++ E D   + +++ 
Sbjct: 349 KDEINQYVKRFKSLDYQNKGFVTVNDLRRYFKKMGEKVTEDQLHDILSEVDLSRNAQVDL 528

Query: 157 EEFIAIMTG 165
            EF+ +M  
Sbjct: 529 GEFLQLMNA 555
>11425
          Length = 599

 Score = 38.5 bits (88), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 38/145 (26%), Positives = 70/145 (48%), Gaps = 6/145 (4%)
 Frame = -2

Query: 22  LSEEQKQEIKDAFELFDT--DKDQAIDYHELKVAMRALGFDVKKADVLKILKDYDREATG 79
           LS+   ++I + FELFD    +D  +D  ++      LG +  + ++++      +    
Sbjct: 577 LSKSDIEDITEVFELFDFWDGRDGDVDAFKVGDMCFCLGLNPTQ-EIIRKNGGTTKLGEK 401

Query: 80  KITFEDFNEVVTDWILERDP--HEEILKAFKLFDDDDSGKISLRNLRRVARELGENMSDE 137
               E+F  +      E+D     + ++ FK FD +  G IS   LR +   LGE +SD+
Sbjct: 400 AYKLEEFLPIYETISKEKDTGTFADFMEGFKTFDREGQGFISAAELRHLLTGLGERLSDD 221

Query: 138 ELRAMIEEFD--KDGDGEINQEEFI 160
           E+  +I+  D  +D +G +  E+FI
Sbjct: 220 EVDELIKATDTREDLEGNVKYEDFI 146
>04643
          Length = 1881

 Score = 37.0 bits (84), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 20/54 (37%), Positives = 33/54 (61%), Gaps = 1/54 (1%)
 Frame = +2

Query: 115 SGKISLRNLRRVAREL-GENMSDEELRAMIEEFDKDGDGEINQEEFIAIMTGDI 167
           SG +    ++   R L G++MS+E L  ++ + D DG+G+IN +EF+A  T  I
Sbjct: 2   SGCLCADEIKAHVRALTGDDMSEEALDNLVSKSDADGNGKINYKEFLASWTA*I 163
>27864
          Length = 343

 Score = 37.0 bits (84), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 21/58 (36%), Positives = 32/58 (55%), Gaps = 1/58 (1%)
 Frame = +1

Query: 107 FKLFDDDDSGKISLRNLRR-VARELGENMSDEELRAMIEEFDKDGDGEINQEEFIAIM 163
           F+  D D SG IS+  L++ ++       + E +R MI  FD+D  G IN +EF A+ 
Sbjct: 31  FQRIDKDRSGNISVNELQQALSNGTWTPFNPETVRLMIGMFDRDNSGTINFQEFQALW 204
>26849
          Length = 649

 Score = 36.2 bits (82), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 20/69 (28%), Positives = 37/69 (53%), Gaps = 2/69 (2%)
 Frame = +2

Query: 94  ILERDPHE--EILKAFKLFDDDDSGKISLRNLRRVARELGENMSDEELRAMIEEFDKDGD 151
            L R P     + +AF++ D D S  +SL   ++   ++  ++++ ++  M   FD DG+
Sbjct: 140 CLSRGPTGILGLARAFRVMDKDGSKVLSLEEFKKGILDMHIDINEADIEDMFYRFDNDGN 319

Query: 152 GEINQEEFI 160
           G IN  EF+
Sbjct: 320 GTINMTEFL 346
>03616
          Length = 2372

 Score = 34.7 bits (78), Expect = 0.018,   Method: Compositional matrix adjust.
 Identities = 17/53 (32%), Positives = 32/53 (60%)
 Frame = +2

Query: 107 FKLFDDDDSGKISLRNLRRVARELGENMSDEELRAMIEEFDKDGDGEINQEEF 159
           F  +D D +G IS+ N+R + R L   + D+ + A++++   D +G I+ E+F
Sbjct: 899 FLRYDRDRTGYISVENMRDLCRRLQLPVDDDVILALVQQCTMDQEGRISLEDF 1057
>17977
          Length = 445

 Score = 34.3 bits (77), Expect = 0.028,   Method: Compositional matrix adjust.
 Identities = 17/64 (26%), Positives = 34/64 (53%)
 Frame = +3

Query: 101 EEILKAFKLFDDDDSGKISLRNLRRVARELGENMSDEELRAMIEEFDKDGDGEINQEEFI 160
            ++++AF+ +D D  GKI + +LR   R+    +    L  + +  D++ DG+I+  EF 
Sbjct: 219 PDLIRAFRFYDKDGKGKIDIDDLREACRKFDVPIDVWLLEQVFDYCDENRDGQIDYLEFA 398

Query: 161 AIMT 164
             + 
Sbjct: 399 NFLN 410
>00167
          Length = 2176

 Score = 33.9 bits (76), Expect = 0.033,   Method: Compositional matrix adjust.
 Identities = 21/59 (35%), Positives = 32/59 (54%), Gaps = 1/59 (1%)
 Frame = +3

Query: 103 ILKAFKLFDDDDSGKISLRNLRRVARELG-ENMSDEELRAMIEEFDKDGDGEINQEEFI 160
           I + F++ DD+   K+S+       RE     M+ EEL  +   FDKDG G ++ EEF+
Sbjct: 735 IGRKFRIMDDNRDRKLSVDEFIVGCRECRIAKMTSEELNEVFRRFDKDGTGTLDFEEFL 911
>19942
          Length = 367

 Score = 33.9 bits (76), Expect = 0.035,   Method: Compositional matrix adjust.
 Identities = 16/30 (53%), Positives = 21/30 (70%)
 Frame = +2

Query: 126 VARELGENMSDEELRAMIEEFDKDGDGEIN 155
           V   LGE ++DEE+  MI E D DGDG++N
Sbjct: 2   VMTNLGEKLTDEEVDEMIREADIDGDGQVN 91
>19912
          Length = 865

 Score = 33.9 bits (76), Expect = 0.036,   Method: Compositional matrix adjust.
 Identities = 17/54 (31%), Positives = 30/54 (55%)
 Frame = +2

Query: 107 FKLFDDDDSGKISLRNLRRVARELGENMSDEELRAMIEEFDKDGDGEINQEEFI 160
           F  FD + +  I+    R+   E    ++ +E+  +++E D+DGDGEIN  E +
Sbjct: 686 FNKFDKEGTMSITRDQFRQGLTEASIPLAGDEVDFLLDELDRDGDGEINYSELV 847
>28617
          Length = 348

 Score = 33.5 bits (75), Expect = 0.047,   Method: Compositional matrix adjust.
 Identities = 15/25 (60%), Positives = 19/25 (76%)
 Frame = -2

Query: 139 LRAMIEEFDKDGDGEINQEEFIAIM 163
            R M+EE D +GDG+I+Q EFI IM
Sbjct: 344 WREMVEEADVNGDGQIDQSEFIRIM 270
>22273
          Length = 297

 Score = 32.7 bits (73), Expect = 0.071,   Method: Compositional matrix adjust.
 Identities = 14/23 (60%), Positives = 18/23 (78%)
 Frame = +1

Query: 142 MIEEFDKDGDGEINQEEFIAIMT 164
           MI E D DGDG++N EEF+ +MT
Sbjct: 10  MIREADIDGDGQVNYEEFVKMMT 78
>26019
          Length = 1561

 Score = 30.8 bits (68), Expect = 0.27,   Method: Compositional matrix adjust.
 Identities = 20/61 (32%), Positives = 37/61 (60%)
 Frame = +2

Query: 100 HEEILKAFKLFDDDDSGKISLRNLRRVARELGENMSDEELRAMIEEFDKDGDGEINQEEF 159
           ++ + K F+  D D+SG +S+     +  EL +N     ++ +I+ FD DG+GE++ +EF
Sbjct: 95  NQRLGKRFRKLDLDNSGSLSIDEFMSLP-ELQQN---PLVQRVIDIFDTDGNGEVDFKEF 262

Query: 160 I 160
           I
Sbjct: 263 I 265
>01773
          Length = 1950

 Score = 30.4 bits (67), Expect = 0.34,   Method: Compositional matrix adjust.
 Identities = 21/64 (32%), Positives = 30/64 (46%)
 Frame = +1

Query: 28  QEIKDAFELFDTDKDQAIDYHELKVAMRALGFDVKKADVLKILKDYDREATGKITFEDFN 87
           Q++ + F+  D   D  +D  ELK  +   G      DV  ILK  D+    KI FE+F 
Sbjct: 367 QKLAELFKAKDKSGDGYLDRDELKALLDESGQKFTADDVSAILKSADKNNDNKICFEEFV 546

Query: 88  EVVT 91
           +  T
Sbjct: 547 DACT 558
>15966
          Length = 362

 Score = 30.0 bits (66), Expect = 0.47,   Method: Compositional matrix adjust.
 Identities = 21/64 (32%), Positives = 30/64 (46%)
 Frame = +2

Query: 28  QEIKDAFELFDTDKDQAIDYHELKVAMRALGFDVKKADVLKILKDYDREATGKITFEDFN 87
           Q++ + F+  D   D  +D  ELK  +   G      DV  ILK  D+    KI FE+F 
Sbjct: 134 QKLAELFKAKDKSGDGYLDRDELKALLDESGQKFTADDVSAILKSADKNNDNKICFEEFV 313

Query: 88  EVVT 91
           +  T
Sbjct: 314 DACT 325
>05230
          Length = 843

 Score = 29.6 bits (65), Expect = 0.67,   Method: Compositional matrix adjust.
 Identities = 19/56 (33%), Positives = 30/56 (53%)
 Frame = -2

Query: 105 KAFKLFDDDDSGKISLRNLRRVARELGENMSDEELRAMIEEFDKDGDGEINQEEFI 160
           K F  FD D SG  S  ++      +G  ++  +LRA I+  D + DG+IN  +F+
Sbjct: 629 KLFAQFDTDGSGWASREDVIEGLENIGITIT-PDLRAKIKAMDGNKDGKINYADFL 465
>07678
          Length = 958

 Score = 28.9 bits (63), Expect = 0.95,   Method: Compositional matrix adjust.
 Identities = 16/60 (26%), Positives = 30/60 (50%), Gaps = 1/60 (1%)
 Frame = +1

Query: 103 ILKAFKLFDDDDSGKISLRNLRRVARELG-ENMSDEELRAMIEEFDKDGDGEINQEEFIA 161
           + + FK+ DDD +  +  +  ++   E G      + ++ M   FDKD  G I+ +EF+ 
Sbjct: 325 LARKFKIMDDDGNRSLDFKEFKKGITEFGLTQFEGDVIQEMFTCFDKDZSGTIDFDEFLV 504
>35350
          Length = 339

 Score = 28.1 bits (61), Expect = 2.0,   Method: Compositional matrix adjust.
 Identities = 15/43 (34%), Positives = 24/43 (55%)
 Frame = +2

Query: 120 LRNLRRVARELGENMSDEELRAMIEEFDKDGDGEINQEEFIAI 162
           L  L+ +  +LG   +   L+ MI E D+D D +I+  EF+ I
Sbjct: 5   LNELKYMMEKLGAPQTHLGLKKMIAEVDEDHDSKISFREFLLI 133
>21620
          Length = 1052

 Score = 28.1 bits (61), Expect = 2.0,   Method: Compositional matrix adjust.
 Identities = 14/44 (31%), Positives = 28/44 (63%)
 Frame = -1

Query: 7   GELVVDKTKRKKRRELSEEQKQEIKDAFELFDTDKDQAIDYHEL 50
           G  VV K + KKRR++S  +K+++  + +L      ++I+Y+E+
Sbjct: 452 GCFVV-KRRIKKRRQMSRNEKKKVWSSLKLCKVH*IRSIEYYEI 324
>16109
          Length = 1490

 Score = 27.3 bits (59), Expect = 3.3,   Method: Compositional matrix adjust.
 Identities = 19/54 (35%), Positives = 28/54 (51%)
 Frame = +3

Query: 33   AFELFDTDKDQAIDYHELKVAMRALGFDVKKADVLKILKDYDREATGKITFEDF 86
            AF   D  KD+ +D  ELK   + +GF +    + +I+  Y  E  GKI  +DF
Sbjct: 1047 AFHTTDVSKDKLVDTFELKDLFKKIGFTIDSEVLKRIVCRYGDE-DGKIHEDDF 1205
>33397
          Length = 1723

 Score = 26.6 bits (57), Expect = 5.6,   Method: Compositional matrix adjust.
 Identities = 8/18 (44%), Positives = 16/18 (88%)
 Frame = +2

Query: 146 FDKDGDGEINQEEFIAIM 163
           FD++ DGE++ +EF+++M
Sbjct: 791 FDENNDGELSNKEFVSVM 844
>32153
          Length = 471

 Score = 26.2 bits (56), Expect = 6.7,   Method: Compositional matrix adjust.
 Identities = 17/61 (27%), Positives = 28/61 (45%), Gaps = 4/61 (6%)
 Frame = -1

Query: 107 FKLFDDDDSGKISLRNLRRV----ARELGENMSDEELRAMIEEFDKDGDGEINQEEFIAI 162
           F   D D  GKI+   L++       ++ E      +R ++   D DGDG I  +E+  +
Sbjct: 408 FNAIDADSDGKITFNELKQNYGNKMLKMMEPFLTIMMRMLMNNADGDGDGLITLQEWYTL 229

Query: 163 M 163
           M
Sbjct: 228 M 226
>08380
          Length = 1236

 Score = 26.2 bits (56), Expect = 7.5,   Method: Compositional matrix adjust.
 Identities = 14/50 (28%), Positives = 27/50 (54%)
 Frame = -1

Query: 118 ISLRNLRRVARELGENMSDEELRAMIEEFDKDGDGEINQEEFIAIMTGDI 167
           +S R+  +  + L  NM    +  ++   D +GDG + +EEF A+  G++
Sbjct: 522 MSFRHPEQSEKTLN-NM----VNGILGGIDTNGDGVVTEEEFSALPPGEV 388
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|7106409|ref|NP_035523.1| excitatory amino acid
transporter 2 isoform 3 [Mus musculus]
         (558 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

19646                                                                 167   2e-41
26838                                                                 109   1e-36
32828                                                                  56   5e-08
12528                                                                  37   0.024
>19646
          Length = 731

 Score =  167 bits (422), Expect = 2e-41,   Method: Compositional matrix adjust.
 Identities = 85/155 (54%), Positives = 112/155 (72%)
 Frame = +2

Query: 341 FSFFAGIFQAWITALGTASSAGTLPVTFRCLEDNLGIDKRVTRFVLPVGATINMDGTALY 400
           F+F   + +A  TA GTASS+ TLPVT  CL     +++R+ RFV P+GATINMDGTALY
Sbjct: 2   FAF--NMLKAICTAWGTASSSATLPVTMDCLVRKNNVNERIVRFVAPIGATINMDGTALY 175

Query: 401 EAVAAIFIAQMNGVILDGGQIVTVSLTATLXXXXXXXXXXXXLVTMLLILTAVGLPTEDI 460
           EAVAAIFIAQ+NG+ L    ++ VSLT+T             LVTM+++LTAV LPTED+
Sbjct: 176 EAVAAIFIAQVNGISLSVADVIVVSLTSTAAAIGAAGVPQAGLVTMVIVLTAVNLPTEDV 355

Query: 461 SLLVAVDWLLDRMRTSVNVVGDSFGAGIVYHLSKS 495
           +L++A+DW LDR RT+VNV GDS GAGI+ H+ ++
Sbjct: 356 TLILAIDWFLDRFRTAVNVWGDSVGAGILNHIFRN 460
>26838
          Length = 787

 Score =  109 bits (272), Expect(3) = 1e-36,   Method: Compositional matrix adjust.
 Identities = 55/97 (56%), Positives = 72/97 (74%)
 Frame = -1

Query: 239 LGLIGFFIAFGIAMGKMGEQAKLMVEFFNILNEIVMKLVIMIMWYSPLGIACLICGKIIA 298
           LG+I F  AFGI +  M E+ K+M++FF  LNEI+MKLV M+MWYSP+GI  LI GKI++
Sbjct: 292 LGIITFCTAFGILISNMRERGKIMMDFFTCLNEIIMKLVAMVMWYSPIGIMFLITGKILS 113

Query: 299 IKDLEVVARQLGMYMITVIVGLIIHGGIFLPLIYFVV 335
           + D   V + LGMYM+TV+ GLIIH  + LP IYFV+
Sbjct: 112 LDDPAKVGQLLGMYMVTVLTGLIIHAVVILPAIYFVI 2

 Score = 55.1 bits (131), Expect(3) = 1e-36,   Method: Compositional matrix adjust.
 Identities = 37/102 (36%), Positives = 53/102 (51%), Gaps = 20/102 (19%)
 Frame = -2

Query: 160 SSLDAFLDLIRNLFPENLVQACFQQIQTVTKKV-LVAPPSEEANTTKAV----------- 207
           +S+DAFLDLIRN+FP+NL+QACFQ  +TV +    + P     N T A+           
Sbjct: 573 TSMDAFLDLIRNIFPDNLLQACFQHTKTVYQDDGFIIPKDLPENVTNAINVTLATTTITT 394

Query: 208 -ISMLNETMNEAPEETKIVIK-------KGLEFKDGMNVLGL 241
            ++ +N+T       T IV+K       +     DG+NVL L
Sbjct: 393 LLTTVNDT-----NATYIVVKEKEIKWIRTFPMADGINVLAL 283

 Score = 27.7 bits (60), Expect(3) = 1e-36,   Method: Compositional matrix adjust.
 Identities = 12/23 (52%), Positives = 14/23 (60%)
 Frame = -3

Query: 110 SGRLGTRAMVYYMSTTIIAAVLG 132
           SGR+G RA+VYY S  I     G
Sbjct: 728 SGRMGLRAIVYYFSYHIFCHHPG 660
>32828
          Length = 643

 Score = 55.8 bits (133), Expect = 5e-08,   Method: Compositional matrix adjust.
 Identities = 41/174 (23%), Positives = 80/174 (45%), Gaps = 8/174 (4%)
 Frame = +2

Query: 383 RFVLPVGATINMDGTALYEAVAAIFIAQMNG-VILDGGQIVTVSLTATLXXXXXXXXXXX 441
            FVLP+ A++N D +A++  +   ++AQ+ G   +D   I+ + +  ++           
Sbjct: 2   SFVLPLVASVNRDASAMFICLTCTYMAQVQGSATVD--TILLILILTSVGSLAIPSMHAA 175

Query: 442 XLVTMLLILTAVGLPTEDISLLVAVDWLLDRMRTSVNVVGDSFGAGIVYHLSK-SELDTI 500
            + T+++I+T++GL   +I +L+A++W  DR+RT+ N    +    + +H  K S  D  
Sbjct: 176 SMATVVMIVTSLGLHPANIGILMALEWFSDRLRTASNNYSHNVCCLVTWHFCKCSXNDPC 355

Query: 501 DSQHRMQED------IEMTKTQSIYDDKNHRESNSNQCVYAAHNSVVIDECKVP 548
                +  D      I+    + +   + H  SN            V +ECK P
Sbjct: 356 PEVGHLFPDMDTSLCIDTDPLKHVACPQEHNSSNG-----------VNNECKCP 484
>12528
          Length = 928

 Score = 36.6 bits (83), Expect = 0.024,   Method: Compositional matrix adjust.
 Identities = 15/27 (55%), Positives = 19/27 (70%)
 Frame = +3

Query: 158 EVSSLDAFLDLIRNLFPENLVQACFQQ 184
           +   LDA LDLIRN FP+NLV   F++
Sbjct: 42  DTKPLDALLDLIRNCFPDNLVTVAFER 122
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|7710096|ref|NP_057876.1| syntrophin, basic 1 [Mus
musculus]
         (537 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

01978                                                                 166   2e-41
20073                                                                  48   9e-06
29705                                                                  47   2e-05
08480                                                                  46   4e-05
38751                                                                  42   6e-04
02951                                                                  30   1.7  
01502                                                                  30   2.4  
>01978
          Length = 946

 Score =  166 bits (421), Expect = 2e-41,   Method: Compositional matrix adjust.
 Identities = 78/151 (51%), Positives = 113/151 (74%), Gaps = 8/151 (5%)
 Frame = -2

Query: 395 LSFATRTGTKQGIETHLFRAEISRDLSHWTRSIVQGCHNSAELTAEITTACTYRNQECRL 454
           LSF TRTGT+ G+ETH+FR E  RDL+ W+R++VQG H +     E+T +  +++++CRL
Sbjct: 888 LSFGTRTGTRHGVETHIFRVETQRDLAFWSRALVQGSHGAVATVKEVTCSVKWKDRKCRL 709

Query: 455 TIHYDNGFSISTEPQ-------DGAFPKTII-QSPYEKLKMSSDDGIRMLYLDFGGKEGE 506
            +HYD GF+++ E +       D   P T++ Q PYE+L+MS+DDG R+L+LDF   +GE
Sbjct: 708 LVHYDTGFTLTEEREEREGGSGDQRPPPTLLWQHPYEQLRMSADDGHRLLWLDF-TDDGE 532

Query: 507 IQLDLHSCPKPIVFIIHSFLSAKITRLGLVA 537
            +LDL++CPKPIVFIIH+FLSAK++RLGL+A
Sbjct: 531 QELDLNTCPKPIVFIIHTFLSAKVSRLGLIA 439
>20073
          Length = 582

 Score = 48.1 bits (113), Expect = 9e-06,   Method: Compositional matrix adjust.
 Identities = 26/58 (44%), Positives = 34/58 (58%)
 Frame = +3

Query: 135 PILISKIFKGLAADQTQALYVGDAILSVNGADLRDATHDEAVQALKRAGKEVLLEVKY 192
           PI IS+I  G  AD+   L  GD +LSVNG  +    H++AV+ LK A   V L V+Y
Sbjct: 45  PIYISRIIPGGVADRLNCLKRGDQLLSVNGVSVEGEYHEKAVELLKLAQGSVRLVVRY 218
>29705
          Length = 674

 Score = 46.6 bits (109), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 24/55 (43%), Positives = 35/55 (63%)
 Frame = -1

Query: 136 ILISKIFKGLAADQTQALYVGDAILSVNGADLRDATHDEAVQALKRAGKEVLLEV 190
           I I+K+ +G +A+Q   + V D +L+VN  +L D TH+EAV ALK  G  V L +
Sbjct: 359 IFITKVIEGGSAEQDGRIAVMDRLLAVNEHNLEDVTHEEAVAALKSTGDVVRLTI 195

 Score = 42.4 bits (98), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 23/59 (38%), Positives = 34/59 (57%)
 Frame = -2

Query: 142 FKGLAADQTQALYVGDAILSVNGADLRDATHDEAVQALKRAGKEVLLEVKYMREATPYV 200
           ++G AA +   L + D I+ V   D+ + TH  AV ALKR+G  V L+VK ++  T  V
Sbjct: 628 YRGGAAAEDGRLRLNDIIVKVGTEDVSNTTHTAAVDALKRSGNRVYLQVKRLKIPTEKV 452
>08480
          Length = 698

 Score = 45.8 bits (107), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 24/46 (52%), Positives = 30/46 (65%)
 Frame = -1

Query: 147 ADQTQALYVGDAILSVNGADLRDATHDEAVQALKRAGKEVLLEVKY 192
           AD +  L  GD ILSVN  D+  ATH++A QALKRAG  V +  +Y
Sbjct: 692 ADLSGDLRRGDKILSVNDVDVERATHEQAAQALKRAGDTVEIIAQY 555
>38751
          Length = 329

 Score = 42.0 bits (97), Expect = 6e-04,   Method: Composition-based stats.
 Identities = 22/48 (45%), Positives = 29/48 (60%)
 Frame = +3

Query: 135 PILISKIFKGLAADQTQALYVGDAILSVNGADLRDATHDEAVQALKRA 182
           PI++  I +G  A+Q Q L +GD IL VNG D    TH EAV  ++ A
Sbjct: 36  PIVVYVIEEGCQAEQ-QGLNIGDRILDVNGTDFTHLTHAEAVTIMRNA 176
>02951
          Length = 1076

 Score = 30.4 bits (67), Expect = 1.7,   Method: Compositional matrix adjust.
 Identities = 19/67 (28%), Positives = 37/67 (55%)
 Frame = +2

Query: 136 ILISKIFKGLAADQTQALYVGDAILSVNGADLRDATHDEAVQALKRAGKEVLLEVKYMRE 195
           I ++ I++   A +   L + D IL +NG D    TH +AV+ ++   K+ +L++   R+
Sbjct: 23  IYVTFIYENSPAARC-GLQLHDKILQLNGKDFTVVTHKQAVENIR---KKPVLKMLVYRK 190

Query: 196 ATPYVKK 202
             P ++K
Sbjct: 191 GVPQLQK 211
>01502
          Length = 1949

 Score = 30.0 bits (66), Expect = 2.4,   Method: Compositional matrix adjust.
 Identities = 16/51 (31%), Positives = 29/51 (56%)
 Frame = +1

Query: 152 ALYVGDAILSVNGADLRDATHDEAVQALKRAGKEVLLEVKYMREATPYVKK 202
            L + D IL +NG D    TH +AV+ ++   K+ +L++   R+  P ++K
Sbjct: 82  GLQLHDKILQLNGKDFTVVTHKQAVENIR---KKPVLKMLVYRKGVPQLQK 225
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31981219|ref|NP_068696.2| guanylate cyclase 1,
soluble, alpha 3 [Mus musculus]
         (691 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

34057                                                                 109   3e-41
25960                                                                  69   9e-12
29215                                                                  51   1e-06
08759                                                                  30   3.0  
01191                                                                  30   3.2  
>34057
          Length = 724

 Score =  109 bits (273), Expect(2) = 3e-41,   Method: Compositional matrix adjust.
 Identities = 55/120 (45%), Positives = 81/120 (67%), Gaps = 1/120 (0%)
 Frame = +3

Query: 440 HQALEEEKKRTVDLLCSIFPSEVAQQLWQGQIVQAKKFSEVTMLFSDIVGFTAICSQCSP 499
           ++  ++EKKRT  LL  + P  VA QL + ++V A+ +SE T+ FSDI GFT I ++ SP
Sbjct: 105 NEGAKQEKKRTDTLLYQMLPKSVADQLKRNEVVTAETYSESTIFFSDIQGFTQISARSSP 284

Query: 500 LQVITMLNALYTRFDQQCGELDVYKVETIGDAYCVAGGLHRES-DTHAVQIALMALKMME 558
           +QV+ MLN+LY  FD++    DVYKVETIGDAY V  G+ +++   HA +I  M L +++
Sbjct: 285 VQVVEMLNSLYLCFDERLALYDVYKVETIGDAYMVVSGVPKKNGKRHAAEIGTMTLDLLD 464

 Score = 77.8 bits (190), Expect(2) = 3e-41,   Method: Compositional matrix adjust.
 Identities = 41/79 (51%), Positives = 49/79 (62%), Gaps = 2/79 (2%)
 Frame = +2

Query: 566 PH--GEPIKMRIGLHSGSVFAGVVGVKMPRYCLFGNNVTLANKFESCSVPRKINVSPTTY 623
           PH  G   K+RIG HSG V AGVVG KMPRYCLFG  V++A K ES   P +I++S TT+
Sbjct: 485 PHLPGTKFKLRIGCHSGPVVAGVVGSKMPRYCLFGETVSVAAKMESLGKPGRIHISQTTH 664

Query: 624 RLLKDCPGFVFTPRSREEL 642
             L    GFV   R  E +
Sbjct: 665 DALLSLGGFVMEQRQDENV 721
>25960
          Length = 420

 Score = 68.6 bits (166), Expect = 9e-12,   Method: Compositional matrix adjust.
 Identities = 40/115 (34%), Positives = 57/115 (49%)
 Frame = +2

Query: 269 GKPQSSLVIPASLFCKTFPFHFMLDRDLAILQLGNGIRRLVNKRDFQGKPNFEEFFEILT 328
           G+  S  V+ A  FC  FP+H + D +L I Q G+ IRR+       G P F     I+ 
Sbjct: 86  GRDFSDSVLKAEDFCSAFPYHIVFDENLGIRQCGDNIRRITQVTITDGLP-FSRIGNIVQ 262

Query: 329 PKINQTFSGIMTMLNMQFVIRVRRWDNSVKKSSRVMDLKGQMIYIVESSAILFLG 383
           P +NQT   I   +N  F++ + R         R   LKGQMI++  S  +LF+G
Sbjct: 263 PVMNQTMENIFKFINAVFLLAIHR---KPGDGDRPFILKGQMIWLKNSRMMLFIG 418
>29215
          Length = 698

 Score = 51.2 bits (121), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 29/65 (44%), Positives = 34/65 (52%), Gaps = 1/65 (1%)
 Frame = -1

Query: 586 VVGVKMPRYCLFGNNVTLANKFESCSVPRKINVSPTTYR-LLKDCPGFVFTPRSREELPP 644
           VVG KMPRYCLFG+ V  A++ ES     KI VS  TY  LL     +   PR   E+  
Sbjct: 698 VVGSKMPRYCLFGDTVNTASRMESTGEADKIQVSRGTYHALLSMTSEYTLEPRGAVEIKG 519

Query: 645 NFPSD 649
             P D
Sbjct: 518 KGPMD 504
>08759
          Length = 2085

 Score = 30.0 bits (66), Expect = 3.0,   Method: Compositional matrix adjust.
 Identities = 15/35 (42%), Positives = 21/35 (60%)
 Frame = +3

Query: 133 KDSLGEELFKICYEEDEHILGVVGGTLKDFLNSFS 167
           + +LGEELF+  +      +G+VGGT   FL S S
Sbjct: 228 RQALGEELFQFLHHVKRRAMGIVGGT---FLGSTS 323
>01191
          Length = 1681

 Score = 30.0 bits (66), Expect = 3.2,   Method: Compositional matrix adjust.
 Identities = 21/67 (31%), Positives = 30/67 (44%), Gaps = 18/67 (26%)
 Frame = +3

Query: 578 HSGSVFAGVVGVKMPRYCLFG------------NNV------TLANKFESCSVPRKINVS 619
           H+    A V   KM R   FG            NNV      TL + F++C +P+K  +S
Sbjct: 681 HTVXSLASVAQKKMKRMHHFGVCYFICLIHLK*NNVSTTKLITLGHAFQTCELPKKFLLS 860

Query: 620 PTTYRLL 626
             T+R+L
Sbjct: 861 RNTFRIL 881
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|40254281|ref|NP_081815.3| doublecortin-like kinase 2
[Mus musculus]
         (756 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

15910                                                                 166   3e-41
14591                                                                 142   4e-34
01392                                                                 127   2e-29
12721                                                                 112   7e-25
14420                                                                 105   8e-23
21079                                                                 102   6e-22
30755                                                                 101   1e-21
17975                                                                 100   2e-21
13592                                                                 100   2e-21
09606                                                                  99   7e-21
01707                                                                  96   5e-20
03240                                                                  95   8e-20
01060                                                                  95   9e-20
14126                                                                  93   4e-19
18921                                                                  90   4e-18
13066                                                                  87   2e-17
00300                                                                  86   5e-17
31885                                                                  86   6e-17
06405                                                                  84   2e-16
02841                                                                  83   3e-16
18484                                                                  82   9e-16
01718                                                                  81   1e-15
00486                                                                  80   2e-15
27546                                                                  74   2e-13
26711                                                                  72   1e-12
29581                                                                  72   1e-12
27405                                                                  70   3e-12
01966                                                                  69   5e-12
19761                                                                  68   2e-11
21433                                                                  67   2e-11
38560                                                                  66   4e-11
11780                                                                  66   6e-11
19094                                                                  65   9e-11
13212                                                                  65   1e-10
28638                                                                  54   1e-10
00392                                                                  64   2e-10
04591                                                                  64   3e-10
21808                                                                  63   5e-10
04852                                                                  61   2e-09
18663                                                                  59   7e-09
12786                                                                  59   1e-08
28157                                                                  58   1e-08
01756                                                                  57   3e-08
20152                                                                  57   3e-08
26560                                                                  56   5e-08
14116                                                                  56   7e-08
09007                                                                  55   1e-07
31489                                                                  55   1e-07
03508                                                                  54   3e-07
07940                                                                  53   4e-07
07291                                                                  53   6e-07
14477                                                                  52   6e-07
19301                                                                  52   7e-07
11185                                                                  50   3e-06
36002                                                                  50   5e-06
12672                                                                  47   3e-05
01106                                                                  46   4e-05
02638                                                                  46   5e-05
25019                                                                  46   6e-05
17722                                                                  45   7e-05
17253                                                                  45   8e-05
11404                                                                  45   9e-05
29590                                                                  45   1e-04
21418                                                                  44   2e-04
04138                                                                  43   4e-04
31120                                                                  43   5e-04
00715                                                                  43   5e-04
18401                                                                  43   6e-04
36481                                                                  43   6e-04
32359                                                                  32   8e-04
26009                                                                  42   8e-04
20655                                                                  42   9e-04
17300                                                                  42   0.001
24241                                                                  40   0.004
37602                                                                  40   0.004
27274                                                                  39   0.006
16708                                                                  39   0.011
32957                                                                  38   0.012
17982                                                                  38   0.018
17516                                                                  37   0.029
00638                                                                  37   0.031
21210                                                                  37   0.039
29360                                                                  36   0.046
33586                                                                  35   0.092
18481                                                                  35   0.11 
07836                                                                  35   0.12 
21800                                                                  35   0.13 
22005                                                                  33   0.42 
00394                                                                  33   0.44 
31789                                                                  32   0.94 
06854                                                                  30   3.0  
16350                                                                  30   3.7  
>15910
          Length = 1361

 Score =  166 bits (421), Expect = 3e-41,   Method: Compositional matrix adjust.
 Identities = 87/223 (39%), Positives = 137/223 (61%), Gaps = 2/223 (0%)
 Frame = +2

Query: 475 DLFDAITSSTKYTERDGSAMVYNLANALRYLHSLSIVHRDIKPENLLVCEYPDGTKSLKL 534
           +LFD I +  +YTE+D +  + ++ + ++Y+H+  +VHRD+KPENLL     D +K LKL
Sbjct: 422 ELFDRIVTRGQYTEKDAARAISDILHGVQYIHANGVVHRDLKPENLLYECMTDDSK-LKL 598

Query: 535 GDFGLATVVEGP--LYTVCGTPTYVAPEIIAETGYGLKVDVWAAGVITYILLCGFPPFRS 592
            DFGL+ ++E    + TVCGTP Y APE++    Y   VD+W+ GVI YILLCG+ PF +
Sbjct: 599 ADFGLSRIIEPEVQMSTVCGTPGYCAPEVLKGDKYTPSVDMWSVGVIAYILLCGYEPFFA 778

Query: 593 ENNLQEDLFDQILAGKLEFPAPYWDNITDSAKELISQMLQVNVEARCTAGEILSHPWVSD 652
           EN  +  ++ +I+ G+ +F   YW  I+++AK+++ ++L ++ + R TA E L  PWV  
Sbjct: 779 ENEFE--MYRKIIKGEYKFDEEYWSEISENAKDVVRKLLVIDPKKRLTATEALRLPWVKG 952

Query: 653 DASQENNMQAEVTGKLKQHFNNALPKQNSTTTGVSVIMNTALD 695
            A++  NM+  +  KLK+   NA  K    T  + VI     D
Sbjct: 953 VATKTTNMEITM-NKLKEF--NARRKLKCATDAMLVIAKATTD 1072
>14591
          Length = 1324

 Score =  142 bits (358), Expect = 4e-34,   Method: Compositional matrix adjust.
 Identities = 82/258 (31%), Positives = 136/258 (52%), Gaps = 54/258 (20%)
 Frame = +1

Query: 69  KKAKKARFYRNGDRYFKGLVFAISNDRFRSFDALLIELTRSLSDNVNLPQGVRTIYTIDG 128
           ++ +K RF+ NGDR+FKG    I+  R+ +F  LL +LT  L  ++NLP GVR I+T  G
Sbjct: 52  RRPRKVRFFVNGDRFFKGKKLHITPHRYYNFTDLLNDLTGKLPSSINLPYGVRQIFTPVG 231

Query: 129 SRKVTSLDELLEGESYVCASNEPFRKVDYTKNVNPNW----------------------- 165
            R+V+ +++L +GE+YVCA  E F+ + Y +     W                       
Sbjct: 232 GRRVSDIEDLQDGETYVCAGFEGFKVIKYGRTELEPWSVGKSGRLGPLQENEAAPDASYG 411

Query: 166 SVNIKGGTTRTL-------AVASAKSEVKESKDF----------------------IKPK 196
           S   +G  T          + A+  + V+ ++ +                      IKPK
Sbjct: 412 SYKYRGYATNAFHPGRYYRSNAAQGNGVQPTRRWPGTFGNQRNTGGLLTAPGEAVPIKPK 591

Query: 197 LVTVIRSGVKPRKAVRILLNKKTAHSFEQVLTDITEAI--KLDSGVVKRLCTLDGKQVTC 254
           ++T+IR+G +PR  ++ILLN+++  S+EQ+++DI+EA   K  S  ++RL T+ G+++  
Sbjct: 592 VITIIRNGQRPRNNIKILLNRRSIQSYEQLMSDISEAFGPKWKSNRIQRLYTMRGREIKG 771

Query: 255 LQDFFGDDDVFIACGPEK 272
           + DFF DDD F+A G E+
Sbjct: 772 VADFFRDDDCFVALGNER 825
>01392
          Length = 1806

 Score =  127 bits (318), Expect = 2e-29,   Method: Compositional matrix adjust.
 Identities = 70/189 (37%), Positives = 107/189 (56%), Gaps = 26/189 (13%)
 Frame = -1

Query: 488  ERDGSAMVYNLANALRYLHSLSIVHRDIKPENLLVCEYPDGTKSLKLGDFGLATVVE--- 544
            ER+ S +V ++A AL +LHS  I HRD+KPEN+L CE+ D    +K+ DF LA+ +    
Sbjct: 1794 EREASLVVRHIARALDFLHSKGIAHRDLKPENIL-CEHLDDVVPVKICDFDLASGISCDG 1618

Query: 545  -----GPLYTVCGTPTYVAPEII-AETG----YGLKVDVWAAGVITYILLCGFPPFRSE- 593
                   L T  G+  Y+APE++ A  G    Y  + D+W+ G+I YI+LCG+PPF  + 
Sbjct: 1617 DGTKTPELLTPVGSAEYMAPEVVDAWVGDSFSYDKRCDLWSLGIILYIMLCGYPPFYGQC 1438

Query: 594  ------------NNLQEDLFDQILAGKLEFPAPYWDNITDSAKELISQMLQVNVEARCTA 641
                        ++ Q+ LF+ I  G  +FP+  W +I+ SAK+LI  +L      R +A
Sbjct: 1437 GEDCGWNRGEACHDCQDMLFNSIQDGHYKFPSQEWTSISSSAKDLIRHLLVREPRKRYSA 1258

Query: 642  GEILSHPWV 650
             ++L HPW+
Sbjct: 1257 ADVLKHPWI 1231
>12721
          Length = 821

 Score =  112 bits (279), Expect = 7e-25,   Method: Compositional matrix adjust.
 Identities = 78/249 (31%), Positives = 131/249 (52%), Gaps = 6/249 (2%)
 Frame = +1

Query: 399 IGDGNFAVVKECVDRYTGKEFALKIIDKAKCCGKEHLIENEVSILRRVKHPNIIMLVEEM 458
           IG+G+  +V     R  G++ A+K +D  K   +E L+ NEV ++R   HPNI+ +    
Sbjct: 112 IGEGSTGIVCIATSR-DGRQMAVKKMDLRKQQRRE-LLFNEVVVMRDYHHPNIVEMYNSY 285

Query: 459 ETATDLFLVMELVKGGDLFDAITSSTKYTERDGSAMVYNLANALRYLHSLSIVHRDIKPE 518
               +L++VME ++GG L D +T++ +  E   + +      AL +LH+  ++HRDIK +
Sbjct: 286 LVNDELWVVMEFMEGGALTDIVTNN-RMDEVQIATVCRACLKALAFLHANGVIHRDIKSD 462

Query: 519 NLLVCEYPDGTKSLKLGDFGLATVVEGPLY---TVCGTPTYVAPEIIAETGYGLKVDVWA 575
           ++L+    DG   +KL DFG    V   L    ++ GTP ++APE+I+   YG +VD+W+
Sbjct: 463 SILLSH--DG--KVKLXDFGFCAQVTQDLQKRKSLVGTPYWMAPEVISRLPYGPEVDIWS 630

Query: 576 AGVITYILLCGFPPFRSENNLQEDLFDQILAGKLEFPAPYWDN---ITDSAKELISQMLQ 632
            G++   ++   PPF +E  LQ       +    + P P   N   I+   +  I +ML 
Sbjct: 631 LGIMVMEMIDAEPPFFNEPPLQA------MRRIRDMPPPKLRNTHKISPRLQGFIDRMLV 792

Query: 633 VNVEARCTA 641
            +   R TA
Sbjct: 793 RDPHQRATA 819
>14420
          Length = 528

 Score =  105 bits (261), Expect = 8e-23,   Method: Compositional matrix adjust.
 Identities = 60/169 (35%), Positives = 98/169 (57%), Gaps = 3/169 (1%)
 Frame = +2

Query: 432 KEHLIENEVSILRRVKHPNIIMLVEEMETATDLFLVMELVKGGDLFDAITSSTKYTERDG 491
           K+ LI NE+ ++R  ++PNI+  ++      +L++VME + GG L D +T  T   E   
Sbjct: 29  KKELIINEILVMRENQNPNIVNYLDSYLVGEELWVVMEFLAGGSLTDVVTE-TCMDEGQI 205

Query: 492 SAMVYNLANALRYLHSLSIVHRDIKPENLLVCEYPDGTKSLKLGDFGLATVV---EGPLY 548
           +A+      AL +LH   ++HRDIK +N+L+    DG  S+KL DFG    +   +    
Sbjct: 206 AAVCRECLQALEFLHENQVIHRDIKSDNILLGM--DG--SVKLTDFGFCAQLSPEQSKRS 373

Query: 549 TVCGTPTYVAPEIIAETGYGLKVDVWAAGVITYILLCGFPPFRSENNLQ 597
           T+ GTP ++APE++    YG  VD+W+ GV+   ++ G PP+ +EN L+
Sbjct: 374 TMVGTPYWMAPEVVTRKQYGPTVDIWSLGVMCIEMIEGEPPYLNENPLR 520
>21079
          Length = 878

 Score =  102 bits (254), Expect = 6e-22,   Method: Compositional matrix adjust.
 Identities = 57/153 (37%), Positives = 83/153 (54%), Gaps = 3/153 (1%)
 Frame = +1

Query: 448 HPNIIMLVEEMETATDLFLVMELVKGGDLFD-AITSSTKYTERDGSAMVYNLANALRYLH 506
           HP ++ML +  E    + LVME V  G+LF+  I      TERD    V  + + + Y+H
Sbjct: 1   HPKLLMLWDAFEAPRTMVLVMEFVGAGELFERVIRDDFVLTERDCVHFVRQICSGVGYMH 180

Query: 507 SLSIVHRDIKPENLLVCEYPDGTKSLKLGDFGLATVVE--GPLYTVCGTPTYVAPEIIAE 564
           + SI+H D+KPEN+L     D +  +K+ DFGLA   +    L  + GTP ++APE++  
Sbjct: 181 TQSILHLDLKPENVLCVS--DNSNQIKIIDFGLARFYKPGDSLQVLFGTPEFIAPEVVNY 354

Query: 565 TGYGLKVDVWAAGVITYILLCGFPPFRSENNLQ 597
                  D+W+ GVI YILL G  P R    L+
Sbjct: 355 DEINFTTDMWSIGVICYILLSGLSPSRVTTMLR 453
>30755
          Length = 1137

 Score =  101 bits (251), Expect = 1e-21,   Method: Compositional matrix adjust.
 Identities = 64/164 (39%), Positives = 91/164 (55%), Gaps = 10/164 (6%)
 Frame = +2

Query: 498 LANALRYLHSLSIVHRDIKPENLLVCEYPDGTKSLKLGDFGLATVVEGPLY-----TVCG 552
           + +AL YLHS  I++RD+K ENLL+    D    +K+ DFGL    E   Y     T CG
Sbjct: 59  IISALGYLHSQGIIYRDLKLENLLL----DKDGHIKVADFGLCK--EDITYGRTTKTFCG 220

Query: 553 TPTYVAPEIIAETGYGLKVDVWAAGVITYILLCGFPPFRSENNLQEDLFDQILAGKLEFP 612
           TP Y+APE++ +  YG  VD W  GV+ Y ++CG  PF + ++  + LF  IL   ++FP
Sbjct: 221 TPEYLAPEVLDDNDYGRAVDWWGTGVVMYEMICGRLPFYNRDH--DVLFTLILVEDVKFP 394

Query: 613 APYWDNITDSAKELISQMLQVNVEARCTAG-----EILSHPWVS 651
                NITD AK L+S +L  +   R   G     EI +HP+ +
Sbjct: 395 R----NITDEAKSLLSGLLAKDPRNRLGGGQDDVKEIQAHPFFA 514
>17975
          Length = 449

 Score =  100 bits (250), Expect = 2e-21,   Method: Composition-based stats.
 Identities = 56/142 (39%), Positives = 85/142 (59%), Gaps = 3/142 (2%)
 Frame = +3

Query: 403 NFAVVKECVDRYTGKEFALKIIDKAKC--CGKEHLIENEVSILRRVKHPNIIMLVEEMET 460
           +FAVVK     +TG++ A+K+IDK K     + HL + EV  ++ V+HPN++ L E ++T
Sbjct: 3   HFAVVKLARHVFTGEKVAVKVIDKTKLDEVSRSHLFQ-EVRCMKLVQHPNVVRLYEVIDT 179

Query: 461 ATDLFLVMELVKGGDLFDAITS-STKYTERDGSAMVYNLANALRYLHSLSIVHRDIKPEN 519
            T L+L++EL  GGD++D I   S    E+        +  A+ Y H L +VHRD+KPEN
Sbjct: 180 QTKLYLILELGDGGDMYDYIMRHSGGLEEKLAKRYFRQIVEAISYCHKLHVVHRDLKPEN 359

Query: 520 LLVCEYPDGTKSLKLGDFGLAT 541
           ++  E P     +KL DFG +T
Sbjct: 360 VVFFEKPG---LVKLTDFGFST 416
>13592
          Length = 980

 Score =  100 bits (250), Expect = 2e-21,   Method: Compositional matrix adjust.
 Identities = 81/289 (28%), Positives = 132/289 (45%), Gaps = 15/289 (5%)
 Frame = +2

Query: 399 IGDGNFAVVKECVDRYTGKEFALKIIDKAKCCGKEHLIEN---EVSILRRVKHPNIIMLV 455
           IG G F  V   V+  TG+  A+K I  A   G+   ++N   E+ IL  +KH N++   
Sbjct: 8   IGQGRFGKVYTAVNNNTGELMAMKEI--AIQPGETRALKNVAEELKILEGIKHKNLVRYY 181

Query: 456 EEMETATDLFLVMELVKGGDLFDAITSSTKYTERDGSAMVYNLANALRYLHSLSIVHRDI 515
                  +L + MEL   G L   +  +    E         L + +  LH   IVHRDI
Sbjct: 182 GIEVHREELLIFMELCSEGTLESLVELTGGLPEALSRRFTAQLLSGVAELHKHGIVHRDI 361

Query: 516 KPENLLVCEYPDGTKSLKLGDFGLA------TVVEGPLYTVCGTPTYVAPEIIAET---G 566
           K  N+ +    DG+ SLKLGDFG A      T V G L    GT  Y+APE+  +T   G
Sbjct: 362 KTANIFLV---DGSNSLKLGDFGSAVKIQAHTTVPGELQGYVGTQAYMAPEVFTKTNSDG 532

Query: 567 YGLKVDVWAAGVITYILLCGFPPFRSENNLQEDLFDQILAGKLEFPAPYWDNITDSAKEL 626
           +G   D+W+ G +   +  G  P+   ++  + +F   +  K + P    ++++    + 
Sbjct: 533 HGRLADIWSVGCVVVEMASGKRPWAQFDSNFQIMFKVGMGEKPQAP----ESLSQEGHDF 700

Query: 627 ISQMLQVNVEARCTAGEILSHPWVSDDASQENN---MQAEVTGKLKQHF 672
           I   LQ + + R +A E+L   +      +E N   + A++ G  +++ 
Sbjct: 701 IDHCLQHDPKQRLSAIELLEQNFCKSGRDEECNSEQLHAQMRGSFRRNM 847
>09606
          Length = 1300

 Score = 99.0 bits (245), Expect = 7e-21,   Method: Compositional matrix adjust.
 Identities = 81/311 (26%), Positives = 131/311 (42%), Gaps = 34/311 (10%)
 Frame = -3

Query: 390  LEKYRIGKVIGDGNFAVVKECVDRYTGKEFALKIIDKAKCCGKEHLIENEVSILRRVKHP 449
            +E + + + +G G  +++ +   + T    A+  I+K K       + N V +   + HP
Sbjct: 1118 MENFVLYEELGKGEHSIIYKGRRKGTINFVAIHCIEKCK----RPEVTNTVRMTHDISHP 951

Query: 450  NIIMLVEEMETATDLFLVMELVKGGDLFDAITSSTKYTERDGSAMVYNLANALRYLHSLS 509
            N++   E  ET+  L+LV+EL  GG L D +       E        +L   L Y+HSL 
Sbjct: 950  NVVQFHEWYETSNHLWLVVELCTGGSLADILAQDHHLPETSIRDFGIHLVTGLHYIHSLG 771

Query: 510  IVHRDIKPENLLVCEYPDGTKSLKLGDFGLATV----VEGPLYTVC-------------- 551
            I+  D++P  +L+    D +  LK  DFGL+ V    +E   +                 
Sbjct: 770  ILFHDLRPSKVLL----DTSGVLKFADFGLSKVEGENLEELFFKFAEAGDQWNIQSAEEM 603

Query: 552  -------GTPTYVAPEIIAETGYGLKVDVWAAGVITYILLCGFPPFRSENNLQEDLFDQI 604
                   G+PTY+APE+       +  D+WA G + Y +  G PPF  E     D+    
Sbjct: 602  MKQVPTSGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFSGHPPFLGETY---DITKDK 432

Query: 605  LAGKLEFPAPYWDNITDSAK------ELISQMLQVNVEARCTAGEILSHPWVSDDAS--- 655
            +  K EFP P       SAK       L+  +LQ +   R +   ++ H +     S   
Sbjct: 431  VLNK-EFPLPKVKGSRLSAKPSPEFLNLLESLLQKDSTRRLSWASLVKHAFWQGGLSSLV 255

Query: 656  QENNMQAEVTG 666
            +E  M  E+ G
Sbjct: 254  KEFTMSEEIGG 222
>01707
          Length = 757

 Score = 95.9 bits (237), Expect = 5e-20,   Method: Compositional matrix adjust.
 Identities = 67/203 (33%), Positives = 107/203 (52%), Gaps = 6/203 (2%)
 Frame = +1

Query: 390 LEKY-RIGKVIGDGNFAVVKECVDRYTGKEFALK-IIDKAKCCGKEHLIENEVSILRRVK 447
           +EKY +IGK IG+G++ VV +C ++ T +  A+K  ++       + +   E+ +L+++K
Sbjct: 61  MEKYEKIGK-IGEGSYGVVFKCRNKETSQLVAIKKFVESEDDPLIKKIAMREIRMLKQLK 237

Query: 448 HPNIIMLVEEMETATDLFLVMELVKGGDLFDAITSSTKYTERDGSAMVYNLANALRYLHS 507
           HPN++ L+E       L LV + V    L +         E     ++Y    A+ + H 
Sbjct: 238 HPNLVRLIEVFRRKKRLHLVFDYVDHTLLNELDRYPRGLPEPMVKRIIYQTLLAVNFCHQ 417

Query: 508 LSIVHRDIKPENLLVCEYPDGTKSLKLGDFGLATVVEGP--LYT-VCGTPTYVAPE-IIA 563
            + +HRD+KPEN+L+         +KL DFG A ++ GP   YT    T  Y APE ++ 
Sbjct: 418 YNTIHRDVKPENILITR----QGQVKLCDFGFARILTGPGDEYTDYVATRWYRAPELLVG 585

Query: 564 ETGYGLKVDVWAAGVITYILLCG 586
           +T YG  VDVWA G +   LL G
Sbjct: 586 DTQYGPPVDVWAIGCVFAELLTG 654
>03240
          Length = 1683

 Score = 95.1 bits (235), Expect = 8e-20,   Method: Compositional matrix adjust.
 Identities = 80/308 (25%), Positives = 127/308 (41%), Gaps = 57/308 (18%)
 Frame = -3

Query: 397  KVIGDGNFAVVKECVDRYTGKEFALKIIDKAKCCGKEHL--IENEVSILRRVKHPNIIML 454
            K +G G F  V  C    TG  +A+K + K+    +  +  ++ E  IL    +  ++ L
Sbjct: 1273 KTLGVGAFGEVSLCRKNDTGMLYAMKTLRKSDVLKRNQVAHVKAERDILAEADNEWVVKL 1094

Query: 455  VEEMETATDLFLVMELVKGGDLFDAITSSTKYTERDGSAMVYNLANALRYLHSLSIVHRD 514
                +    L+ VM+ V GGDL   +       E      V  L  A+  +H +  +HRD
Sbjct: 1093 YYSFQDHNYLYFVMDYVPGGDLMGLLIRMEILDEPLARFYVAELVQAIESVHRMGFIHRD 914

Query: 515  IKPENLLVCEYPDGTKSLKLGDFGLAT--------------------------------- 541
            IKP+N+L+    D    +KL DFGL T                                 
Sbjct: 913  IKPDNILI----DRNGHIKLTDFGLCTGFRWTHNSKYYQRDGTHARQDSMEVKCQLDEQC 746

Query: 542  --VVEGPL------------YTVCGTPTYVAPEIIAET-GYGLKVDVWAAGVITYILLCG 586
               +  PL            +++ GTP Y+APE+++   GY    D W+ GVI + +L G
Sbjct: 745  QCEILKPLERRRKREQRCLAHSLVGTPNYIAPEVLSRLGGYTSVCDWWSVGVILFEMLVG 566

Query: 587  FPPFRSENNLQEDLFDQILAGKLEFPAPYWDNITDSAKELISQM-------LQVNVEARC 639
             PPF +  N   +   +++  K     P   N++  AK+LI ++       L +N     
Sbjct: 565  HPPFYA--NTPAETQYKVINWKDMLKIPRESNLSQPAKDLILRLCCGSDDRLGLN----- 407

Query: 640  TAGEILSH 647
             AGEI +H
Sbjct: 406  GAGEIKTH 383
>01060
          Length = 1800

 Score = 95.1 bits (235), Expect = 9e-20,   Method: Compositional matrix adjust.
 Identities = 67/211 (31%), Positives = 108/211 (51%), Gaps = 11/211 (5%)
 Frame = +1

Query: 399 IGDGNFAVVKECVDRYTGKEFALKIIDKAKCCGKEHLIEN----EVSILRRVKHPNIIML 454
           IG+G + VV +C  R TG++ A+K   K +  G E  + +    E+++LR ++H NI+ L
Sbjct: 97  IGEGTYGVVYKCRHRATGRKLAMK---KIRLRGSEDGVPSSAIREIAMLRELRHTNIVCL 267

Query: 455 VEEMETATDLFLVMELVKGGDL---FDAITSSTKYTERDGSAMVYNLANALRYLHSLSIV 511
            + +     LFLV E +   DL    D          R   + V+ +   + + H   IV
Sbjct: 268 EDVIMEDERLFLVFEFL-SMDLKMYIDKFPEGVVLDRRLVKSYVFQIVTGIXFCHQRRIV 444

Query: 512 HRDIKPENLLVCEYPDGTKSLKLGDFGLATVVEGPL--YT-VCGTPTYVAPEII-AETGY 567
           HRD+KP+NLL+    + T ++K+ DFG+A     P+  YT    T  Y APEI+   + Y
Sbjct: 445 HRDLKPQNLLI----NHTGAIKIADFGMARTFALPVRAYTHEVVTLWYRAPEILMGASKY 612

Query: 568 GLKVDVWAAGVITYILLCGFPPFRSENNLQE 598
              VDVW+ G I   +L   P F+ ++ + +
Sbjct: 613 STPVDVWSIGTIFADMLIRTPIFKGDSEIDQ 705
>14126
          Length = 1265

 Score = 92.8 bits (229), Expect = 4e-19,   Method: Compositional matrix adjust.
 Identities = 100/325 (30%), Positives = 154/325 (47%), Gaps = 43/325 (13%)
 Frame = +3

Query: 372 CLSPEGVNGNRCSESFPLL--------EKYRIGKVIGDGNFAVVKECVD-RYTGKEFALK 422
            +SP+G +G   SES   +        +KY    VIG+G +  V +  D R  G+  A+K
Sbjct: 114 AISPKGRDGQ--SESAAKMSRRRDSTEQKYEEVAVIGNGAYGTVYKARDLRNQGEFVAMK 287

Query: 423 IIDKAKCC-GKEHLIENEVSILRRVK---HPNIIMLVE-EMETATD----LFLVMELVKG 473
            I       G   +   E+S+L++++   HPN++ L++    T TD    L LV E ++ 
Sbjct: 288 RIRLNNTEEGMPMMAIREISMLKQLEQYEHPNVVRLLDVSHNTITDREIRLNLVFEYIEH 467

Query: 474 GDL--FDAITSSTKYTERDGSAMVYNLANALRYLHSLSIVHRDIKPENLLVCEYPDGTKS 531
            DL  + A   S          ++  L N + +LHS  IVHRD+KP+NLL+ +  DG   
Sbjct: 468 -DLATYLAKCPSPGLGPDRIKDLMLQLLNGVDFLHSNRIVHRDLKPQNLLISK--DG--R 632

Query: 532 LKLGDFGLATV--VEGPLYTVCGTPTYVAPEIIAETGYGLKVDVWAAGVITYILLCGFPP 589
           LKL DFGLA +      L TV  T  Y +PE++ +  YG  VD+W+ G I   L      
Sbjct: 633 LKLADFGLARIYSFHMALTTVVVTLWYRSPEVLMQAEYGTSVDIWSCGCIFAELFTRRAL 812

Query: 590 FR--SENNLQEDLFDQI---LAG-------------KLEFPAPYWDNITD---SAKELIS 628
           F+  SE +  + +F+ I    AG             +   P P    + +    AK+L+ 
Sbjct: 813 FKGSSEFDQLKKIFEVIGLPPAGDWPEGVSVHRNSFRPTPPVPLQTLVPEMDPQAKDLME 992

Query: 629 QMLQVNVEARCTAGEILSHPWVSDD 653
           +ML      R ++ E L HP++ DD
Sbjct: 993 KMLVFKSGRRISSRESLLHPYLRDD 1067
>18921
          Length = 697

 Score = 89.7 bits (221), Expect = 4e-18,   Method: Compositional matrix adjust.
 Identities = 62/199 (31%), Positives = 100/199 (50%), Gaps = 4/199 (2%)
 Frame = +2

Query: 395 IGKVIGDGNFAVVKECVDRYTGKEFALKIIDKAKCCGKEHLIENEVSILRRVKHPNIIML 454
           +GK +G+G++  V + + + TG+  A+K   +         I  E+SI+++     I+  
Sbjct: 44  LGK-LGEGSYGSVFKSLHKETGQVLAIK---QVPVDTDLQEIIKEISIMQQCDSKYIVKY 211

Query: 455 VEEMETATDLFLVMELVKGGDLFDAITSSTK-YTERDGSAMVYNLANALRYLHSLSIVHR 513
                  TDL++VME    G + D +    K   ER+ + ++Y     L YLHS   +HR
Sbjct: 212 YGSYFKNTDLWIVMEYCGAGSVSDIMRLRNKTLVEREIATILYYTLKGLXYLHSRRKIHR 391

Query: 514 DIKPENLLVCEYPDGTKSLKLGDFGLATVVEGPLY---TVCGTPTYVAPEIIAETGYGLK 570
           DIK  N+L+    +     KL DFG+A  +   +    TV GTP ++APE+I E GY   
Sbjct: 392 DIKAGNILL----NNEGHAKLADFGVAGQLTDTMAKRNTVIGTPYWMAPEVIQEIGYDCV 559

Query: 571 VDVWAAGVITYILLCGFPP 589
            D+W+ G+    +  G PP
Sbjct: 560 ADIWSLGITALEMAEGKPP 616
>13066
          Length = 551

 Score = 87.4 bits (215), Expect = 2e-17,   Method: Compositional matrix adjust.
 Identities = 57/169 (33%), Positives = 79/169 (46%), Gaps = 9/169 (5%)
 Frame = +3

Query: 418 EFALKIIDKAKCCGK--EHLIENEVSILRRVKHPNIIMLVEEMETATDLFLVMELVKGGD 475
           + A KIIDK K      E     E+ +L ++ HP II +   ++     F+ M   + GD
Sbjct: 57  KLACKIIDKEKAPVDFVEKFFPRELDLLTKLDHPYIIQIHSILQRXPKNFIFMRFAERGD 236

Query: 476 LFDAITSSTKYTERDGSAMVYNLANALRYLHSLSIVHRDIKPENLLVCEYPDGTKSLKLG 535
           L   I       E+      Y +  AL YLHS  + HRD+K EN+L+  + +    +KL 
Sbjct: 237 LLTYIQEVGFVKEKQAKIWFYQMTTALNYLHSYDVAHRDLKCENILLSSHFN----VKLA 404

Query: 536 DFGLATVV---EGPLY---TVCGTPTYVAPEIIAETGYGLKV-DVWAAG 577
           DFG A       G  Y   T CG+  Y APEI+    Y  KV D W+ G
Sbjct: 405 DFGFACACITESGEKYMSRTYCGSAAYAAPEIVYGAPYAPKVADAWSLG 551
>00300
          Length = 2318

 Score = 86.3 bits (212), Expect = 5e-17,   Method: Compositional matrix adjust.
 Identities = 68/268 (25%), Positives = 121/268 (45%), Gaps = 12/268 (4%)
 Frame = -1

Query: 392  KYRIGKVIGDGNFAVVKECVDRYTGKEFALKIIDKAKCCGKEHLIE--NEVSILRRVKHP 449
            +++ G  IG+G F  V   V+  TG+  ALK + K +    + L E  +E+ I   ++H 
Sbjct: 1655 RWQRGNKIGEGQFGKVYTAVNMSTGELMALKEM-KFQPNDLQQLREMCDEIKIFEGIQHE 1479

Query: 450  NIIMLVEEMETATDLFLVMELVKGGDLFDAITSS-TKYTERDGSAMVYNLANALRYLHSL 508
            N++          ++ + ME    G + +A      +Y  R        +  A+ +LH  
Sbjct: 1478 NLVKYYGVEVHKDEMLMFMEYCDTGTIEEAAKMGLPEYLIR---RYTREIVLAVNHLHEN 1308

Query: 509  SIVHRDIKPENLLVCEYPDGTKSLKLGDFGLA------TVVEGPLYTVCGTPTYVAPEII 562
            SIVHRDIK  N+ +         +KLGDFG +      T + G  + + GT  Y+APE+ 
Sbjct: 1307 SIVHRDIKGANIFLT----SNGHVKLGDFGCSVKLKSHTTMPGEFHNLVGTTAYMAPEVF 1140

Query: 563  AET---GYGLKVDVWAAGVITYILLCGFPPFRSENNLQEDLFDQILAGKLEFPAPYWDNI 619
             +    GYG   D+W+ G +   +  G  P+   +N  + ++   +  K   P    D++
Sbjct: 1139 TQNDQGGYGRAADIWSLGCVVIEMATGKRPWHDLDNNYQIMYKVGIGHKPAVP----DSL 972

Query: 620  TDSAKELISQMLQVNVEARCTAGEILSH 647
            +   K  +  ++  +   R  A ++L H
Sbjct: 971  SVEGKHFLDLIMCHDPAQRALASQLLDH 888
>31885
          Length = 529

 Score = 85.9 bits (211), Expect = 6e-17,   Method: Compositional matrix adjust.
 Identities = 57/163 (34%), Positives = 80/163 (49%), Gaps = 7/163 (4%)
 Frame = -2

Query: 440 VSILRRVKHPNIIMLVEEMETATDLFLVMELVKGGDLFDAITSSTKYTERDGSAMVYNLA 499
           V +L R+ HP ++ L    +   DLF+V++L  GGDL   +     + E      +  LA
Sbjct: 519 VDMLTRLDHPFLVNLWYAFQDEEDLFMVVDLFLGGDLRYHMQQEVSFREDCVKFYLCQLA 340

Query: 500 NALRYLHSLSIVHRDIKPENLLVCEYPDGTKSLKLGDFGLATVVEGP--LYTVCGTPTYV 557
             L YL S  IVHRDIKP+N+L+    D      + DF +AT +E      +  GT  Y+
Sbjct: 339 LVLDYLRSQKIVHRDIKPDNILL----DEQGHCHVTDFNIATQLEDDELATSTSGTRPYM 172

Query: 558 APEIIA-----ETGYGLKVDVWAAGVITYILLCGFPPFRSENN 595
           APE+         GYG  VD W+ GV  + LL    PF   +N
Sbjct: 171 APEVYGVAINERRGYGFPVDWWSLGVSLFELLKKRRPFSVHSN 43
>06405
          Length = 1965

 Score = 84.0 bits (206), Expect = 2e-16,   Method: Compositional matrix adjust.
 Identities = 56/200 (28%), Positives = 102/200 (51%), Gaps = 8/200 (4%)
 Frame = +1

Query: 399 IGDGNFAVVKECVDRYTGKEFALKIIDKAKCCGKEHLIENEVSILRRVKHPNIIMLVEEM 458
           +G G +  V E + +   K  A+K + +      + L   E +I++ +KHPN++ L+   
Sbjct: 283 LGGGQYGDVYEAMWKRYNKIVAVKTLKEDTMALNDFL--EEAAIMKEMKHPNLVQLLGVC 456

Query: 459 ETATDLFLVMELVKGGDLFDAITSSTKYTERDGSAMVY---NLANALRYLHSLSIVHRDI 515
                 ++V E +  G+L D + SST+  E   +A++Y    +A+ + YL + + +HRD+
Sbjct: 457 TREPPFYIVTEFMPHGNLLDYLRSSTR-EENGPTALMYMATQIASGMAYLETKNFIHRDL 633

Query: 516 KPENLLVCEYPDGTKSLKLGDFGLATVVEGPLYTV---CGTP-TYVAPEIIAETGYGLKV 571
              N LV +    +  +K+ DFGLA +++   YT       P  + APE +A   +  + 
Sbjct: 634 AARNCLVAD----SNMVKVADFGLARLMKDDTYTAHIGAKFPIKWTAPEGLAFNRFSTRS 801

Query: 572 DVWAAGVITYILLC-GFPPF 590
           D+WA GV+ + L   G  P+
Sbjct: 802 DIWAFGVLLWELATYGMSPY 861
>02841
          Length = 1442

 Score = 83.2 bits (204), Expect = 3e-16,   Method: Compositional matrix adjust.
 Identities = 36/82 (43%), Positives = 59/82 (71%), Gaps = 2/82 (2%)
 Frame = +3

Query: 193 IKPKLVTVIRSGVKPRKAVRILLNKKTAHSFEQVLTDITEAI--KLDSGVVKRLCTLDGK 250
           +KP+++T++R+G +PR  V++LLN+++  SFEQ++ DI+EA   K  +  V++L T  GK
Sbjct: 327 LKPRVITIVRNGHRPRTNVKLLLNRRSIQSFEQLMADISEAFGPKWKNNRVQKLYTTHGK 506

Query: 251 QVTCLQDFFGDDDVFIACGPEK 272
           +V  + DFF +DD FIA G E+
Sbjct: 507 EVNSVSDFFREDDCFIAMGNER 572
>18484
          Length = 635

 Score = 81.6 bits (200), Expect = 9e-16,   Method: Compositional matrix adjust.
 Identities = 46/141 (32%), Positives = 72/141 (51%), Gaps = 3/141 (2%)
 Frame = +1

Query: 475 DLFDAITSSTKYTERDGSAMVYNLANALRYLHSLSIVHRDIKPENLLVCEYPDGTKSLKL 534
           DL   I    K+ E   +     +A  L +LH   I++RD+K +N+++    D    +K+
Sbjct: 1   DLMYRIQQEGKFKEPVAAFYAAEIAVGLFFLHDQGIIYRDLKLDNVML----DSEGHIKI 168

Query: 535 GDFGL---ATVVEGPLYTVCGTPTYVAPEIIAETGYGLKVDVWAAGVITYILLCGFPPFR 591
            DFG+       +    T CGTP Y+APEI+    Y   VD WA GV+ + +L G PPF 
Sbjct: 169 ADFGMCKEGMTGDATTRTFCGTPDYIAPEIVLYQPYSKSVDWWAYGVLLFEMLAGQPPFD 348

Query: 592 SENNLQEDLFDQILAGKLEFP 612
            E+  +++LF  I    + +P
Sbjct: 349 GED--EDELFSSITDHNVSYP 405
>01718
          Length = 959

 Score = 81.3 bits (199), Expect = 1e-15,   Method: Compositional matrix adjust.
 Identities = 55/192 (28%), Positives = 91/192 (47%), Gaps = 7/192 (3%)
 Frame = +3

Query: 395 IGKVIGDGNFAVVKECVDRYTGKEFALKIIDKAKCCGKEHLIENEVSILRRVKHPNIIML 454
           I + IG G F+ V +   R TG+  ALK+          H +  EV +L R++H NI+  
Sbjct: 159 ICEKIGAGFFSEVFKVTHRITGQVMALKM---NTMTSNRHNMLREVQLLNRLQHANILRF 329

Query: 455 VEEMETATDLFLVMELVKGGDL---FDAITSSTKYTERDGSAMVYNLANALRYLHSLSIV 511
           +        L  + E +  G+L    +       +T+R    +   LA  L YLHS   +
Sbjct: 330 MGVCVHEGQLHALTEYIPSGNLEQLLEKKDEELPWTQR--IQLTLGLARGLDYLHSTRFI 503

Query: 512 HRDIKPENLLVCEYPDGTKSLKLGDFGLATVVEGPL----YTVCGTPTYVAPEIIAETGY 567
           HRD+  +N+L+    +      + DFGLAT +  PL        G+P ++APE++    Y
Sbjct: 504 HRDLTSKNILIRREDNHGYHAVIADFGLATKIPDPLDKEKLPTVGSPYWMAPEVLNGHFY 683

Query: 568 GLKVDVWAAGVI 579
             + D+++ G+I
Sbjct: 684 NERADLFSVGII 719
>00486
          Length = 797

 Score = 80.5 bits (197), Expect = 2e-15,   Method: Compositional matrix adjust.
 Identities = 43/101 (42%), Positives = 60/101 (59%)
 Frame = -2

Query: 548 YTVCGTPTYVAPEIIAETGYGLKVDVWAAGVITYILLCGFPPFRSENNLQEDLFDQILAG 607
           +T CGT  Y+APEI+  TG+G  VD W+ G + Y +L G PPF +EN  ++   D+IL G
Sbjct: 784 HTFCGTIEYMAPEILTRTGHGKAVDWWSLGALMYDMLTGSPPFTAEN--RKKTIDKILKG 611

Query: 608 KLEFPAPYWDNITDSAKELISQMLQVNVEARCTAGEILSHP 648
           KL  P PY   +T+ A+ LI ++L+ N   R   G   S P
Sbjct: 610 KLNLP-PY---LTNEARGLIKKLLRKNPAERLGGGHDDSGP 500
>27546
          Length = 426

 Score = 74.3 bits (181), Expect = 2e-13,   Method: Composition-based stats.
 Identities = 44/127 (34%), Positives = 65/127 (51%), Gaps = 2/127 (1%)
 Frame = -1

Query: 416 GKEFALKIIDKAKCCGK--EHLIENEVSILRRVKHPNIIMLVEEMETATDLFLVMELVKG 473
           G   A KIIDKAK      +     E+ IL R+ HPNII +   ++    +F+ M   + 
Sbjct: 405 GVNLACKIIDKAKAPIDFVKKFFPRELEILTRLDHPNIIQIHSILQRGPKIFIFMRYAEK 226

Query: 474 GDLFDAITSSTKYTERDGSAMVYNLANALRYLHSLSIVHRDIKPENLLVCEYPDGTKSLK 533
           GD+   I  +    E       + +A AL+YLHS  I HRD+K EN+L+ +      ++K
Sbjct: 225 GDMLSHIKKTGPIDEAQTKVWFFQMAKALQYLHSHDIAHRDLKCENILLSK----RLNVK 58

Query: 534 LGDFGLA 540
           + DFG A
Sbjct: 57  IADFGFA 37
>26711
          Length = 405

 Score = 71.6 bits (174), Expect = 1e-12,   Method: Composition-based stats.
 Identities = 44/137 (32%), Positives = 71/137 (51%), Gaps = 2/137 (1%)
 Frame = -2

Query: 493 AMVYNLANALRYLHSLSIVHRDIKPENLLVCEYPDGTKSLKLGDFGLATVVEGPLYTVC- 551
            +V  + + L+++H+  +VH D+KP NLL+    D   S++L DFGLA  +  P  T   
Sbjct: 404 GVVKQVLDILQHVHAQGVVHMDLKPSNLLLSG--DKLDSVQLIDFGLARKLYPPQETFLN 231

Query: 552 -GTPTYVAPEIIAETGYGLKVDVWAAGVITYILLCGFPPFRSENNLQEDLFDQILAGKLE 610
            GTP + +PE +         DVW  GV+ YILL G  PF++++  +     Q      +
Sbjct: 230 HGTPGFTSPEALDVKPISTASDVWGVGVLAYILLSGQSPFQADSATESLKKTQTCDWSFD 51

Query: 611 FPAPYWDNITDSAKELI 627
              P + N++  AK+ I
Sbjct: 50  V-CPSFSNMSQDAKDFI 3
>29581
          Length = 1278

 Score = 71.6 bits (174), Expect = 1e-12,   Method: Compositional matrix adjust.
 Identities = 71/263 (26%), Positives = 115/263 (43%), Gaps = 32/263 (12%)
 Frame = -2

Query: 441  SILRRVKHPNIIMLVEEM--ETATDLFLVMELVKG--GDLFDAITSSTKYTERDGSAMVY 496
            + L  ++H NI+ L E +  ++   LFLVME  +     L D + +   ++E     +V 
Sbjct: 1199 TFLLNLRHQNIVQLQEVVVGKSLDSLFLVMEYCEQDLASLLDNMPAP--FSESQVKCIVL 1026

Query: 497  NLANALRYLHSLSIVHRDIKPENLLVCEYPDGTKSLKLGDFGLATVV---EGPLYTVCGT 553
             L   LRYLH   I+HRD+K  NLL+ +       +K+ DFGLA      + P+     T
Sbjct: 1025 QLLKGLRYLHEAFIIHRDLKVSNLLMTD----KGCVKIADFGLARNYGKPQKPMTPKVVT 858

Query: 554  PTYVAPEII-AETGYGLKVDVWAAGVITYILLCGFPPFRSENNLQE-----DLF----DQ 603
              Y APE++     +   +D+W+AG I   LL   P     ++LQ+     +L     D 
Sbjct: 857  LWYRAPELLFGSKTHSTAIDMWSAGCILGELLGHKPLMPGRSDLQQIELIMELLGTPNDT 678

Query: 604  ILAGKLEFPA---------PY------WDNITDSAKELISQMLQVNVEARCTAGEILSHP 648
            I  G  + PA         PY      +  +++S   L++ +   + + R TA + L H 
Sbjct: 677  IWPGFSQLPAFEQFTLKKQPYNNLRHTFPWLSESGIRLLNGLFMYHPQKRATAEDCLEHS 498

Query: 649  WVSDDASQENNMQAEVTGKLKQH 671
            +  +   Q      E      QH
Sbjct: 497  YFKE---QPYPCDPEFMPSFPQH 438
>27405
          Length = 532

 Score = 70.1 bits (170), Expect = 3e-12,   Method: Compositional matrix adjust.
 Identities = 50/167 (29%), Positives = 82/167 (49%), Gaps = 7/167 (4%)
 Frame = -3

Query: 403 NFAVVKECVDRYTGKEFALKIIDKA--KCCGKEHLIENEVSILRRVK----HPNIIMLVE 456
            F  V  C    TGK +A+K +DK   K  G E L  NE  +L  V      P I+ +  
Sbjct: 530 GFGEVYGCRKADTGKMYAMKCLDKKRIKMKGGETLALNERIMLSLVSTGEGSPFIVCMTY 351

Query: 457 EMETATDLFLVMELVKGGDLFDAITSSTKYTERDGSAMVYNLANALRYLHSLSIVHRDIK 516
             +T   L  +++L+ GGDL   ++    +TE++       +   L ++HS  +V+RD+K
Sbjct: 350 AFQTPEKLCFILDLMNGGDLHYHLSQHGVFTEKEVRFYAAEVMLGLEHMHSRFVVYRDLK 171

Query: 517 PENLLVCEYPDGTKSLKLGDFGLAT-VVEGPLYTVCGTPTYVAPEII 562
           P N+L+    D    +++ D GLA    +   +   GT  Y+APE++
Sbjct: 170 PANILL----DENGHVRISDLGLACDFSKKKPHASVGTHGYMAPEVL 42
>01966
          Length = 1735

 Score = 69.3 bits (168), Expect = 5e-12,   Method: Compositional matrix adjust.
 Identities = 55/180 (30%), Positives = 86/180 (47%), Gaps = 10/180 (5%)
 Frame = -1

Query: 410  CVDRYTGKEFALKIIDKAKCCGKEHLIEN----EVSILRRVKHPNIIMLVEEMETATDLF 465
            C  R TG++ A+K   K +  G E  + +    E+++LR ++H NI+ L + +     LF
Sbjct: 1654 CRHRATGRKLAMK---KIRLRGSEDGVPSSAIREIAMLRELRHTNIVCLEDVIMEDERLF 1484

Query: 466  LVMELVKGGDL---FDAITSSTKYTERDGSAMVYNLANALRYLHSLSIVHRDIKPENLLV 522
            LV E +   DL    D          R   + V+ +   + + H   IVHRD+KP+NLL+
Sbjct: 1483 LVFEFL-SMDLKMYIDKFPEGVVLDRRLVKSYVFQIVTGINFCHQRRIVHRDLKPQNLLI 1307

Query: 523  CEYPDGTKSLKLGDFGLATVVEGPL--YT-VCGTPTYVAPEIIAETGYGLKVDVWAAGVI 579
                + T ++K+ DFG+A     P+  YT    T  Y APEI+   G       W  G +
Sbjct: 1306 ----NHTGAIKIADFGMARTFALPVRAYTHEVVTLWYRAPEIL--MGPQSTPPXWTCGAL 1145
>19761
          Length = 473

 Score = 67.8 bits (164), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 47/142 (33%), Positives = 76/142 (53%), Gaps = 9/142 (6%)
 Frame = -3

Query: 499 ANALRYLHSLS--IVHRDIKPENLLVCEYPDGTKSLKLGDFGLATVVEGPL---YTVCGT 553
           A+AL Y+H+ +  I+HRD+KP+N+ V E  D    ++LGD GLA  + GP     +  GT
Sbjct: 393 ASALNYMHTHTPVILHRDLKPQNIYVTEKGD----VRLGDLGLARKLTGPADFATSQVGT 226

Query: 554 PTYVAPEIIAETGYGLKVDVWAAGVITYILLCGFPPFRSENNLQED----LFDQILAGKL 609
             Y++PEI+++  Y  K D+W+ G       C F     +    E     L  Q++ G+ 
Sbjct: 225 IMYLSPEILSQQPYNSKSDIWSLG-------CVFYDITGKKGSDEMGVMFLLVQVMGGR- 70

Query: 610 EFPAPYWDNITDSAKELISQML 631
           + P P  D+ +   ++ IS+ML
Sbjct: 69  KLPLP--DHYSQEFRDTISRML 10
>21433
          Length = 590

 Score = 67.4 bits (163), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 49/146 (33%), Positives = 73/146 (50%), Gaps = 8/146 (5%)
 Frame = +2

Query: 495 VYNLANALRYLHSLSIVHRDIKPENLLVCEYPDGTKSLKLGDFGLATVVEGP---LYTVC 551
           +Y L++AL Y H   ++HRDIKPENLL+         LK+ DFG +  V  P     T+C
Sbjct: 185 IYQLSSALEYCHYRKVIHRDIKPENLLL----GLKGDLKIADFGWS--VHAPSSRRTTMC 346

Query: 552 GTPTYVAPEIIAETGYGLKVDVWAAGVITYILLCGFPPFRSENNLQEDLFDQILAGKLEF 611
           GT  Y+ PE++    +   VD+W+ GV+ Y  L G PP R                    
Sbjct: 347 GTLDYLPPEMVEGKTHDENVDLWSLGVLCYEFLVGTPPLRPSPTRPPTPA---------- 496

Query: 612 PAPYWDN-----ITDSAKELISQMLQ 632
            +P W +     +T  A++LIS++L+
Sbjct: 497 -SPRWTSGSPSIVTPGARDLISKLLR 571
>38560
          Length = 479

 Score = 66.2 bits (160), Expect = 4e-11,   Method: Compositional matrix adjust.
 Identities = 42/128 (32%), Positives = 64/128 (50%), Gaps = 1/128 (0%)
 Frame = -3

Query: 547 LYTVCGTPTYVAPEIIAETGY-GLKVDVWAAGVITYILLCGFPPFRSENNLQEDLFDQIL 605
           L T CG+P Y APE+I+   Y G + D+W+ GV+ Y LLCG+ PF  E        +Q  
Sbjct: 414 LTTCCGSPAYAAPELISGLEYLGSEADIWSMGVLLYALLCGYLPFDDEKXSHL*QKNQ-- 241

Query: 606 AGKLEFPAPYWDNITDSAKELISQMLQVNVEARCTAGEILSHPWVSDDASQENNMQAEVT 665
             K +   P W  +++   +L+  MLQ +   R T   +L H W+    +Q  N+  E  
Sbjct: 240 --KRKDEVPEW--LSEDTTKLLEGMLQTDPSHRITIRRLLDHHWL----NQGFNVPVEWA 85

Query: 666 GKLKQHFN 673
            K K+  +
Sbjct: 84  SKYKRTLD 61
>11780
          Length = 1713

 Score = 65.9 bits (159), Expect = 6e-11,   Method: Compositional matrix adjust.
 Identities = 53/172 (30%), Positives = 91/172 (52%), Gaps = 2/172 (1%)
 Frame = +3

Query: 395 IGKVIGDGNFAVVKECVDRYTGKEFALKIIDKAKCCGKEHLIENEVSILRRVKHPNIIML 454
           IG+ IG G+F  V + +  Y G+  A+K + K K  G++  ++ E S++  ++H N++ L
Sbjct: 609 IGEAIGKGDFGDVYKGM--YRGQPVAIKQL-KDKDRGEQSFLQ-EASVMTSLRHDNLVRL 776

Query: 455 VEEMETATDLFLVMELVKGGDLFDAITSSTK--YTERDGSAMVYNLANALRYLHSLSIVH 512
           +  +   T +FLV E +  G+L + + S  +   T++D      +   A+ YL S  +VH
Sbjct: 777 IGVVLGET-IFLVTEFMGKGNLVEYLRSRGRSVITKKDQINFATDTCAAMEYLESKRLVH 953

Query: 513 RDIKPENLLVCEYPDGTKSLKLGDFGLATVVEGPLYTVCGTPTYVAPEIIAE 564
           RD+   N+LV  + DG    K+ DFGLA   +    +V     + APE + E
Sbjct: 954 RDLAARNVLV--HDDGKA--KVSDFGLAKFGDFSQTSVKFPIKWTAPEALRE 1097
>19094
          Length = 898

 Score = 65.1 bits (157), Expect = 9e-11,   Method: Compositional matrix adjust.
 Identities = 36/95 (37%), Positives = 53/95 (55%), Gaps = 3/95 (3%)
 Frame = +1

Query: 487 TERDGSAMVYNLANALRYLHSLSIVHRDIKPENLLVCEYPDGTKSLKLGDFGLATVVEGP 546
            ER+ + ++Y     L YLHS   +HRDIK  N+L+    +     KL DFG+A  +   
Sbjct: 52  VEREIATILYYTLKGL*YLHSRRKIHRDIKAGNILL----NNEGHAKLADFGVAGQLTDT 219

Query: 547 LY---TVCGTPTYVAPEIIAETGYGLKVDVWAAGV 578
           +    TV GTP ++APE+I E GY    D+W+ G+
Sbjct: 220 MAKRNTVIGTPYWMAPEVIQEIGYDCVADIWSLGI 324
>13212
          Length = 1067

 Score = 65.1 bits (157), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 52/165 (31%), Positives = 80/165 (48%), Gaps = 10/165 (6%)
 Frame = -1

Query: 496 YNLANALRYLHSLSIVHRDIKPENLLVCEYPDGTKSLKLGDFGLA---TVVEGPLYTVCG 552
           + +  AL +LH   ++HRDIK  N+L+    DG   +KL DFG++   T  +    T  G
Sbjct: 959 HEMCMALDFLHRHHVIHRDIKAGNVLLTI--DG--EVKLADFGVSAKNTQTQQKRDTFIG 792

Query: 553 TPTYVAPEII-----AETGYGLKVDVWAAGVITYILLCGFPPFRSENNLQEDLFD--QIL 605
           TP ++APE++      +T Y  K D+W+ GV T I      P   E +    L    +  
Sbjct: 791 TPYWMAPEVVLCETLKDTPYDFKADIWSLGV-TLIEFAQIEPPNKEMHPMRVLIKIHKSD 615

Query: 606 AGKLEFPAPYWDNITDSAKELISQMLQVNVEARCTAGEILSHPWV 650
              LE P  +    T   K+ I++ L  +   R TA E+L HP++
Sbjct: 614 PPTLEKPKKW----TKLFKDFIAKCLVKDPNLRPTAAELLEHPFM 492
>28638
          Length = 1458

 Score = 53.5 bits (127), Expect(2) = 1e-10,   Method: Compositional matrix adjust.
 Identities = 30/96 (31%), Positives = 52/96 (54%), Gaps = 2/96 (2%)
 Frame = -1

Query: 497 NLANALRYLHS--LSIVHRDIKPENLLVCEYPDGTKSLKLGDFGLATVVEGPLYTVCGTP 554
            L  AL +L +  ++I+H D+KPEN+L+C       ++K+ DFG +  +   +Y    + 
Sbjct: 813 QLCTALLFLATPEMNIIHCDLKPENILLCN--PKRSAIKIVDFGSSCQLGQRIYQYIQSR 640

Query: 555 TYVAPEIIAETGYGLKVDVWAAGVITYILLCGFPPF 590
            Y +PE++    Y L +D+W+ G I   +  G PP 
Sbjct: 639 FYRSPEVLLGVPYDLAIDMWSLGCILVEMHTGEPPL 532

 Score = 31.2 bits (69), Expect(2) = 1e-10,   Method: Compositional matrix adjust.
 Identities = 27/99 (27%), Positives = 47/99 (47%), Gaps = 4/99 (4%)
 Frame = -3

Query: 390  LEKYRIGKVIGDGNFAVVKECVDRYTGKEFALKIIDKAKCCGKEHLIENE-VSILRRVKH 448
            L++Y I  +IG G+F  V +  D    ++ A+KII   K    +  IE + + ++ R   
Sbjct: 1150 LDRYEIDSLIGKGSFGQVVKAYDHGDQEQVAIKIIKNKKPFLNQAQIEVKLLELMNRHDA 971

Query: 449  PN---IIMLVEEMETATDLFLVMELVKGGDLFDAITSST 484
             N   I+ L         L LV EL+   +L+D + ++ 
Sbjct: 970  DNXYYIVRLKRHFMFRNHLCLVFELL-SYNLYDLLRNTN 857
>00392
          Length = 668

 Score = 64.3 bits (155), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 50/182 (27%), Positives = 88/182 (48%), Gaps = 8/182 (4%)
 Frame = +3

Query: 436 IENEVSILRRVKHPNIIMLVEEMETATD-----LFLVMELVKGGDLFDAITSSTKYTERD 490
            + E  +L+ ++HPNI+   +  E         + LV EL+  G L   +    K   + 
Sbjct: 72  FKEEAEMLKELQHPNIVRFFDYWEEHNHRNRKVIILVTELMTSGTLKTYLKRFKKPNVKI 251

Query: 491 GSAMVYNLANALRYLHSLS--IVHRDIKPENLLVCEYPDGTKSLKLGDFGLATVVEGPLY 548
                  +   L +LH+ +  ++HRD+K +N+ +      T S+K+GD GLAT+      
Sbjct: 252 LKNWCRQVLKGLYFLHTRTPPVIHRDLKCDNIFIT---GPTGSVKIGDLGLATLKNQSFA 422

Query: 549 -TVCGTPTYVAPEIIAETGYGLKVDVWAAGVITYILLCGFPPFRSENNLQEDLFDQILAG 607
            +V GTP ++APE+  E  Y   VDV+A G+    +     P+ SE +    ++ ++ +G
Sbjct: 423 KSVIGTPEFMAPEMYEE-HYDEAVDVYAFGMCMLEMASSEYPY-SECSNAAQIYKRVTSG 596

Query: 608 KL 609
            L
Sbjct: 597 VL 602
>04591
          Length = 1117

 Score = 63.5 bits (153), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 49/153 (32%), Positives = 76/153 (49%), Gaps = 12/153 (7%)
 Frame = -2

Query: 439  EVSILRRVKHPNIIMLVEEMETA--------TDLFLVMELVKGGDLFDAITS-STKYTER 489
            E+ IL++++H N++ L E   T         +  +L+ E     DL   + +   K++  
Sbjct: 1071 EIKILQQLEHENVVQLQEICHTQAGPYNRYKSTFYLIFEYCDY-DLAGLLNNLRVKFSLA 895

Query: 490  DGSAMVYNLANALRYLHSLSIVHRDIKPENLLVCEYPDGTKSLKLGDFGLAT--VVEGPL 547
            D   ++  L N L Y+H+  I+HRDIK  N+L+    DG   LKL DFGL+   V    L
Sbjct: 894  DKKNLMSQLLNGLFYIHTKQILHRDIKAANILLTR--DGV--LKLADFGLSRPWVKSKRL 727

Query: 548  YTVCGTPTYVAPE-IIAETGYGLKVDVWAAGVI 579
                 T  Y  PE ++ E  YG ++D+W  G I
Sbjct: 726  TNRVVTLWYRPPELLLGEREYGPEIDMWGVGCI 628
>21808
          Length = 1011

 Score = 62.8 bits (151), Expect = 5e-10,   Method: Compositional matrix adjust.
 Identities = 57/240 (23%), Positives = 104/240 (43%), Gaps = 6/240 (2%)
 Frame = +1

Query: 439 EVSILRRVKHPNIIMLVEEMETATDLFLVMELVKGGDLFDAITSSTKYTERDGSAMV-YN 497
           E  I+++++HP +I L         +F++ EL+K G L + +    +  +      +   
Sbjct: 82  EAQIMKKLRHPKLIQLYAVCTQDDPIFIITELMKNGSLLEFLQGKGRVLKLPALIDIGAQ 261

Query: 498 LANALRYLHSLSIVHRDIKPENLLVCEYPDGTKSLKLGDFGLATVVEGPLYTV---CGTP 554
           +A  + YL S + +HRD+   N+LV +      ++K+ DFGLA V++   Y        P
Sbjct: 262 IACGMAYLESQNYIHRDLAARNILVSD----NNTVKIADFGLARVIKEDEYEARVGARFP 429

Query: 555 T-YVAPEIIAETGYGLKVDVWAAGV-ITYILLCGFPPFRSENNLQEDLFDQILAGKLEFP 612
             + APE      + +K DVW+ G+ +T  +  G  P+    N   ++  Q+  G    P
Sbjct: 430 IKWTAPEAANYNRFTIKSDVWSFGILLTETVTYGRVPYPGMTN--AEVLHQVEHG-YRMP 600

Query: 613 APYWDNITDSAKELISQMLQVNVEARCTAGEILSHPWVSDDASQENNMQAEVTGKLKQHF 672
            P         K L   ML+      C   E +  P + + A +   +      +L++ F
Sbjct: 601 CP-----PGCPKPLYDIMLE------CWRKEEMERPHLRNPAMEAGGILYHGLQRLQRSF 747
>04852
          Length = 1462

 Score = 60.8 bits (146), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 58/229 (25%), Positives = 99/229 (43%), Gaps = 34/229 (14%)
 Frame = +1

Query: 420 ALKIIDKAKCCGKEHLIENEVSILRRVK----HPNIIMLVEEMETATDLFLVMELVKGGD 475
           A+K++       +E     E+ +++ VK    H NI+  +        L++++E  K G+
Sbjct: 31  AVKMLRDIVTAVEEQDFVQELQVMKAVKKMGSHINIVNFLGCCTQGGPLWVIVEFAKNGN 210

Query: 476 LFDAITSSTK----------------YTERDGSAMV---------YNLANALRYLHSLSI 510
           L D + S                   YT+  G  ++         + +A  + +L S   
Sbjct: 211 LRDFLESCRDGINGYGKFVSPQDPGWYTKTPGGHVIRRKNLLSYAFQIARGMEFLASRKC 390

Query: 511 VHRDIKPENLLVCEYPDGTKSLKLGDFGLATVVEGPLY---TVCGTPT-YVAPEIIAETG 566
           +HRD+   N+LV E       LK+ DFGL+    G  Y   +    P  ++APE + +  
Sbjct: 391 IHRDLAARNVLVTE----EHVLKIADFGLSRT--GDYYKKRSGGRLPVKWMAPEALFDMR 552

Query: 567 YGLKVDVWAAGVITY-ILLCGFPPFRSENNLQEDLFDQILAGKLEFPAP 614
           Y  K DVW+ GV+ + I   G  P+ S  N  E+L+ ++L      P P
Sbjct: 553 YTTKSDVWSFGVVLWEIFSLGGMPYASIPN--EELYSKLLDDAYRMPRP 693
>18663
          Length = 600

 Score = 58.9 bits (141), Expect = 7e-09,   Method: Compositional matrix adjust.
 Identities = 32/71 (45%), Positives = 39/71 (54%), Gaps = 7/71 (9%)
 Frame = +2

Query: 549 TVCGTPTYVAPEIIAETGYGLKVDVWAAGVITYILLCGFPPF----RSEN---NLQEDLF 601
           T CGTP Y+APEI+    YG  VD WA GV+ Y +L G  PF     SEN   N ++ LF
Sbjct: 5   TFCGTPNYIAPEILRGEDYGFSVDWWALGVLLYEMLAGRSPFDIAGASENPDQNTEDYLF 184

Query: 602 DQILAGKLEFP 612
             IL   +  P
Sbjct: 185 QVILEKTIRIP 217
>12786
          Length = 460

 Score = 58.5 bits (140), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 37/125 (29%), Positives = 63/125 (50%), Gaps = 26/125 (20%)
 Frame = -3

Query: 498 LANALRYLHSLSIVHRDIKPENLLVCEYPDGTKSLKLGDFGLATVVEGPLYTV-----CG 552
           +  A++ LH+  ++H D+KP N ++        +LKL DFG+A  ++    +V      G
Sbjct: 383 MLRAVKALHNEGVIHSDLKPANFMLV-----AGNLKLIDFGIANTLQQDKTSVLKDSRVG 219

Query: 553 TPTYVAPEIIA------------ETGY--------GLKVDVWAAGVITYILLCGFPPFRS 592
           TP+Y++PE I             E G+        G++ DVW+ G I Y ++ G  PF+ 
Sbjct: 218 TPSYMSPEAIMAACDDSADDSMEEDGHRTKPKYKVGVRSDVWSLGCILYNMVYGRTPFQH 39

Query: 593 -ENNL 596
            +NN+
Sbjct: 38  IKNNM 24
>28157
          Length = 400

 Score = 58.2 bits (139), Expect = 1e-08,   Method: Composition-based stats.
 Identities = 44/130 (33%), Positives = 68/130 (52%), Gaps = 6/130 (4%)
 Frame = +3

Query: 417 KEFALKIIDKAKCCGKEHLIENEVSILRRVKHPNIIMLVEEMETATDLFLVMELVKGGDL 476
           K+ A+K I+  +   ++     E+  L RV HPNI+ L         + LVME  +GG L
Sbjct: 3   KDVAVKRIESEQ---EKKSFMQELKQLSRVSHPNIVCLYGACRDHP-VCLVMEYAEGGSL 170

Query: 477 FDAITSS---TKYTERDGSAMVYNLANALRYLHSL---SIVHRDIKPENLLVCEYPDGTK 530
           ++ +  S    +YT       +   A  + YLH +   +++HRD+KP NLL+ +   GTK
Sbjct: 171 YNVLHGSGPQPQYTAAHAMNWLLQCALGVEYLHGMKPKALIHRDLKPPNLLLIQC--GTK 344

Query: 531 SLKLGDFGLA 540
            LK+ DFG A
Sbjct: 345 -LKICDFGTA 371
>01756
          Length = 1858

 Score = 57.0 bits (136), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 62/214 (28%), Positives = 94/214 (43%), Gaps = 21/214 (9%)
 Frame = -3

Query: 387  FPLLE---KYRIGKVIGDGNFAVVKECVDRYTGKEFALK--IIDKAKCCGKEHLIENEVS 441
            FP  +   KY     IG G F  V +   + T +  A+K  ++D  K  G       E+ 
Sbjct: 1763 FPFCDEDAKYEKLAKIGQGTFGEVFKARCKKTKQVVAMKKVLMDNEKE-GFPITALREIK 1587

Query: 442  ILRRVKHPNIIMLVEEMETATD--------LFLVMELVKGGDLFDAITS-STKYTERDGS 492
            IL+ + H N++ L+E   T            +LV E  +  DL   +++ S  +   +  
Sbjct: 1586 ILQLLNHENVVDLIEICSTKATSANRYKSMFYLVFEFCEH-DLAGLLSNMSVVFNLPEIK 1410

Query: 493  AMVYNLANALRYLHSLSIVHRDIKPENLLVCEYPDGTKSLKLGDFGLATVVEGPL----- 547
             ++  L N L Y+H   I+HRD+K  N+L+ +       LKL DFGLA      L     
Sbjct: 1409 EVMKQLMNGLYYIHRNKILHRDMKAANILITK----QGVLKLADFGLARAFSVNLRQPNR 1242

Query: 548  YT-VCGTPTYVAPE-IIAETGYGLKVDVWAAGVI 579
            YT    T  Y  PE ++ +  Y   +D W AG I
Sbjct: 1241 YTNRVVTLWYRPPELLLGDRNYSTAIDQWGAGCI 1140
>20152
          Length = 445

 Score = 56.6 bits (135), Expect = 3e-08,   Method: Composition-based stats.
 Identities = 32/95 (33%), Positives = 51/95 (53%), Gaps = 1/95 (1%)
 Frame = +1

Query: 559 PEIIAETGY-GLKVDVWAAGVITYILLCGFPPFRSENNLQEDLFDQILAGKLEFPAPYWD 617
           PEI+    Y    VDVW+ GVI Y+L+ G  PF+  N+   +    I+  + + P     
Sbjct: 1   PEILLGDSYDAPAVDVWSLGVILYMLVVGEAPFQEAND--SETLTMIMDCRYQIPP---- 162

Query: 618 NITDSAKELISQMLQVNVEARCTAGEILSHPWVSD 652
           +I+   ++LI +MLQ     R +   IL+HPW++D
Sbjct: 163 HISHKCQDLIEKMLQREPVDRASLPHILAHPWLND 267
>26560
          Length = 398

 Score = 56.2 bits (134), Expect = 5e-08,   Method: Composition-based stats.
 Identities = 37/125 (29%), Positives = 62/125 (49%), Gaps = 2/125 (1%)
 Frame = -1

Query: 475 DLFDAITSSTKYTERDGSAMVYNLANALRYLHSLSIVHRDIKPENLLVCEYPDGTKSLKL 534
           DL   ++    +TE++       +   L ++HS  +V+RD+KP N+L+    D    +++
Sbjct: 398 DLHYHLSQHGVFTEKEVRFYAAEVMLGLEHMHSRFVVYRDLKPANILL----DENGHVRI 231

Query: 535 GDFGLAT-VVEGPLYTVCGTPTYVAPEIIAE-TGYGLKVDVWAAGVITYILLCGFPPFRS 592
            D GLA    +   +   GT  Y+APE++ +   Y    D ++ G + Y LL G  PFR 
Sbjct: 230 SDLGLACDFSKKRPHASVGTHGYMAPEVLMKGQSYDSSADWFSFGCMLYKLLKGHSPFRQ 51

Query: 593 ENNLQ 597
            N  Q
Sbjct: 50  HNQGQ 36
>14116
          Length = 1017

 Score = 55.8 bits (133), Expect = 7e-08,   Method: Compositional matrix adjust.
 Identities = 55/203 (27%), Positives = 89/203 (43%), Gaps = 13/203 (6%)
 Frame = -1

Query: 395 IGKVIGDGNFAVVKECVDRYTGKEFALKIIDKAKCCGKEHLIE-----NEVSILRRVKHP 449
           +G+ IG GNF  VK        ++  + +  K         IE      E  I++   H 
Sbjct: 624 MGEEIGKGNFGCVKRGFLTLPEQKGDILVAVKTLHNNNPREIELQSFLQEALIMKDFHHS 445

Query: 450 NIIMLVEEMETATDL-FLVMELVKGGDLFDAITSST-KYTERDGSAMVYNLANALRYLHS 507
           N++ L+       D+  +V+  +K GDL   I     + T +D      ++A  + YL  
Sbjct: 444 NVLTLIGICLNLDDMPLVVLPFMKHGDLLTYIRDDQHQPTIKDLIMYGVDIARGMDYLAG 265

Query: 508 LSIVHRDIKPENLLVCEYPDGTKSLKLGDFGLA-TVVEGPLYTV----CGTPT-YVAPEI 561
           L  VHRD+   N ++    D    +K+ DFGLA  + E   Y+        P  ++A E 
Sbjct: 264 LKFVHRDLAARNCML----DEDFHVKVADFGLARDIYEKEYYSSENKKAKLPVKWMALES 97

Query: 562 IAETGYGLKVDVWAAGVITYILL 584
           + +  Y  K DVW+ GV+ + LL
Sbjct: 96  LEKGNYDSKTDVWSYGVVLWELL 28
>09007
          Length = 1440

 Score = 55.1 bits (131), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 55/238 (23%), Positives = 102/238 (42%), Gaps = 20/238 (8%)
 Frame = -1

Query: 395 IGKVIGDGNFAVVKECVDRYTGKEFALKIIDKAKCCGKEHLIEN------EVSILRRVKH 448
           + K +G G+F  V++ +  +T  E   K+    KC  K+ + ++      E +I++ + H
Sbjct: 867 LSKSLGQGHFGTVRQAI--WTA-ESGEKVQVAVKCLSKDKIHKDGQEFLKETAIMQMLDH 697

Query: 449 PNIIMLVEE-METATDLFLVMELVKGGDLFDAI---TSSTKYTERDGSAMVYNLANALRY 504
            NI+ +    M+   D+ LV EL     L + +   ++   ++          + + + Y
Sbjct: 696 ENIVRVYGVVMDNGADIMLVTELAPMRSLLECVKEVSARVDFSVPRLCDFSQQVCDGMSY 517

Query: 505 LHSLSIVHRDIKPENLLVCEYPDGTKSLKLGDFGLATVV-EGPLY-------TVCGTPTY 556
           L S  +VHRD+   N+L+         +K+ D G++  +  G  Y        +     +
Sbjct: 516 LESKRLVHRDLAARNILLF----SKSKVKISDVGVSGALGAGKEYYQSQQTIHLQNAVAW 349

Query: 557 VAPEIIAETGYGLKVDVWAAGVITYILLC-GFPPFRSENNLQ-EDLFDQILAGKLEFP 612
            APE      +    DVWA GV+ +     GF P+   N  Q  +  D   + +LE P
Sbjct: 348 CAPESFRNLCFSSASDVWAFGVLLWEFFTHGFQPWAGLNGQQIMEAVDAPQSQRLEQP 175
>31489
          Length = 329

 Score = 55.1 bits (131), Expect = 1e-07,   Method: Composition-based stats.
 Identities = 31/88 (35%), Positives = 48/88 (54%), Gaps = 6/88 (6%)
 Frame = +3

Query: 440 VSILRRVKHPNIIMLVEEMETA------TDLFLVMELVKGGDLFDAITSSTKYTERDGSA 493
           + IL+  KH NII + E ++         D+ +V +L++  DL   I S    TE     
Sbjct: 3   IKILKHFKHDNIISIREILKPKDSYHDFKDIHVVFDLMES-DLHRIIYSDQPLTEEHIRY 179

Query: 494 MVYNLANALRYLHSLSIVHRDIKPENLL 521
            +Y +   L+Y+HS ++VHRD+KP NLL
Sbjct: 180 FLYQILRGLKYIHSANVVHRDLKPSNLL 263
>03508
          Length = 1463

 Score = 53.5 bits (127), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 36/117 (30%), Positives = 57/117 (48%), Gaps = 3/117 (2%)
 Frame = +1

Query: 466 LVMELVKGGDLFDAITSSTKYTERDGSAMVYNLANALRYLHSLSIVHRDIKPENLLVCEY 525
           L+ E V   D      + T Y   D    +Y L  AL + HS+ I+HRD+KP N+++   
Sbjct: 811 LIFEHVNNTDFKQLYQTFTDY---DIRFYLYELMKALDFCHSMGIMHRDVKPHNVMI--- 972

Query: 526 PDGTKSLKLGDFGLATVVE-GPLYTV-CGTPTYVAPEIIAETG-YGLKVDVWAAGVI 579
               K L+L D+GLA     G  Y V   +  +  PE++ +   Y   +D+W+ G +
Sbjct: 973 DHENKKLRLIDWGLAEFYHPGMEYNVRVASRYFKGPELLLDYQMYDYSLDMWSLGCM 1143
>07940
          Length = 1336

 Score = 53.1 bits (126), Expect = 4e-07,   Method: Compositional matrix adjust.
 Identities = 40/122 (32%), Positives = 59/122 (48%), Gaps = 6/122 (4%)
 Frame = -3

Query: 487 TERDGSAMVYNLANALRYLHSLSIVHRDIKPENLLVCEYPDGTKSLKLGDFGLATVVEGP 546
           T +D  +  Y +A  + YL S   +HRD+   N+LV E       LK+ DFGL   ++  
Sbjct: 353 TPKDLISYAYQVARGMEYLASKQCIHRDLAARNVLVAE----EYVLKIADFGLTRNLQQF 186

Query: 547 LYTVCGTP-----TYVAPEIIAETGYGLKVDVWAAGVITY-ILLCGFPPFRSENNLQEDL 600
            Y    T       ++APE + +  Y  K DVW+ GV+ + I   G  P+ S     EDL
Sbjct: 185 DYYRKTTDGRLPVKWMAPEALFDRKYTSKSDVWSYGVLLWEIFTLGGNPYPSVP--VEDL 12

Query: 601 FD 602
           F+
Sbjct: 11  FN 6
>07291
          Length = 833

 Score = 52.8 bits (125), Expect = 6e-07,   Method: Compositional matrix adjust.
 Identities = 34/106 (32%), Positives = 54/106 (50%), Gaps = 7/106 (6%)
 Frame = +1

Query: 497 NLANALRYLHSLSIVHRDIKPENLLVCEYPDGTKSLKLGDFGL-ATVVEGPLYTVCGTPT 555
            +A+ + YL  + +VHR++   N +V E  DG   L+L D+G+  ++     YT   +P 
Sbjct: 73  QIADGMAYLQEVKVVHRNLAARNCIVTE--DG--RLQLSDYGVTGSLFPQSYYTADDSPA 240

Query: 556 -----YVAPEIIAETGYGLKVDVWAAGVITYILLC-GFPPFRSENN 595
                ++APE I    +  K DVWA GV+ + LL  G  P+    N
Sbjct: 241 RDLVKWMAPETIDNFHFSSKSDVWAFGVVLWELLTRGITPYPDVEN 378
>14477
          Length = 493

 Score = 52.4 bits (124), Expect = 6e-07,   Method: Composition-based stats.
 Identities = 39/149 (26%), Positives = 75/149 (50%), Gaps = 4/149 (2%)
 Frame = -1

Query: 399 IGDGNFAVVKECVDRYTGKEF--ALKIIDKAKC--CGKEHLIENEVSILRRVKHPNIIML 454
           +G GNF  V + V R   +E   A+K++  A      +  LI+ E  +++++ H +I+ L
Sbjct: 466 LGAGNFGSVMKGVCRLDDREIPVAIKVLKNADLDPSVQSELIK-EAEVMKKMDHMHIVRL 290

Query: 455 VEEMETATDLFLVMELVKGGDLFDAITSSTKYTERDGSAMVYNLANALRYLHSLSIVHRD 514
           +   E  T + LV+EL K G L   +  +      +   +++ ++  + YL +   VHRD
Sbjct: 289 IGLCEGET-MMLVLELAKLGPLNKFLPKNKHLPLWNILELMWQVSQGMEYLEANKFVHRD 113

Query: 515 IKPENLLVCEYPDGTKSLKLGDFGLATVV 543
           +   N+L+C+        K+ DFG++  +
Sbjct: 112 LAARNILLCD----EHFAKISDFGMSKTL 38
>19301
          Length = 712

 Score = 52.4 bits (124), Expect = 7e-07,   Method: Compositional matrix adjust.
 Identities = 35/110 (31%), Positives = 55/110 (50%), Gaps = 8/110 (7%)
 Frame = +2

Query: 437 ENEVSILRRVKHPNIIMLVEEMETATDLFLVMELVKGGDLFDAITSSTKYTERDGS---- 492
           E ++  LR++ HPNII        A    ++ME    G L++ +        RDG     
Sbjct: 413 ETDIRNLRKLNHPNIISFKGVCTQAPCYCIIMEYCPYGQLYEVL--------RDGKEIPP 568

Query: 493 AMVYN----LANALRYLHSLSIVHRDIKPENLLVCEYPDGTKSLKLGDFG 538
           A+V +    +A+ + YLHS  I+HRD+K  N+LV +       +K+ DFG
Sbjct: 569 ALVLDWSKQIASGMNYLHSHKIIHRDLKSPNVLVAK----NDVVKISDFG 706
>11185
          Length = 473

 Score = 50.4 bits (119), Expect = 3e-06,   Method: Composition-based stats.
 Identities = 33/115 (28%), Positives = 50/115 (43%), Gaps = 25/115 (21%)
 Frame = +1

Query: 497 NLANALRYLHSLSIVHRDIKPENLLVCEYPDGTKSLKLGDFGLATV-------------- 542
           +L   L Y+HSL I+  D++P  +L+    D +  LK  DFGL+ V              
Sbjct: 25  HLVTGLHYIHSLGILFHDLRPSKVLL----DTSGVLKFADFGLSKVEGENLEELFFKFAE 192

Query: 543 ---------VEGPLYTV--CGTPTYVAPEIIAETGYGLKVDVWAAGVITYILLCG 586
                     E  +  V   G+PTY+APE+       +  D+WA G + Y +  G
Sbjct: 193 AGDQWNIQSAEEMMKQVPTSGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFSG 357
>36002
          Length = 253

 Score = 49.7 bits (117), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 24/64 (37%), Positives = 36/64 (56%)
 Frame = +1

Query: 589 PFRSENNLQEDLFDQILAGKLEFPAPYWDNITDSAKELISQMLQVNVEARCTAGEILSHP 648
           P  +  + QE LF++I  G   FP+  W  I+ SAK+LI  +L      R +A ++L HP
Sbjct: 25  PGEACQDCQELLFNRIQDGNYFFPSMEWSAISSSAKDLIRHLLVREPRKRYSAADVLKHP 204

Query: 649 WVSD 652
           WV +
Sbjct: 205 WVCN 216
>12672
          Length = 773

 Score = 46.6 bits (109), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 35/103 (33%), Positives = 51/103 (49%), Gaps = 9/103 (8%)
 Frame = +3

Query: 494 MVYNLANALRYLHSLSIVHRDIKPENLLVCEYPDGTKSLKLGDFGLATVVEGP------- 546
           +V   A+ ++YL+    VHRDIK  N+L+    D   + K+GDF  ATVV  P       
Sbjct: 6   IVKGTASGIQYLNDNGHVHRDIKTANILL----DSEYTAKVGDF--ATVVSAPSGEGKTV 167

Query: 547 --LYTVCGTPTYVAPEIIAETGYGLKVDVWAAGVITYILLCGF 587
                V GT  Y+APE I       K+D ++ GV+   ++ G 
Sbjct: 168 QNASVVIGTAAYLAPEAI-HFDVSTKLDSYSFGVVLLEVITGL 293
>01106
          Length = 878

 Score = 46.2 bits (108), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 38/150 (25%), Positives = 74/150 (49%), Gaps = 18/150 (12%)
 Frame = +3

Query: 392 KYRIGKVIGDGNFAVVKECVDRYTGKEFALKIIDKAKCCGKEHLIE---NEVSILRRVKH 448
           +Y + + +G G+F+ V  C D    +  ALK++  A     +H  E   +EV +L+ V+ 
Sbjct: 321 RYHVIRKLGWGHFSTVWLCWDLTCKRFVALKVVKSA-----QHYTETALDEVKLLKCVRE 485

Query: 449 PNI--------IMLVEEMETA----TDLFLVMELVKGGDLFDAITSST--KYTERDGSAM 494
            ++        + L+++ + +    T + +V E++ G +L   I  S        +   +
Sbjct: 486 SDVADPARAKCVQLLDDFKISGVNGTHVAMVFEVL-GYNLLKLIIRSNYQGIPIHNVKLI 662

Query: 495 VYNLANALRYLHS-LSIVHRDIKPENLLVC 523
           +  +   L Y+H+   I+H DIKPEN+L+C
Sbjct: 663 IRQVLEGLSYMHAKCRIIHTDIKPENILIC 752
>02638
          Length = 1490

 Score = 46.2 bits (108), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 25/97 (25%), Positives = 50/97 (51%)
 Frame = +1

Query: 552 GTPTYVAPEIIAETGYGLKVDVWAAGVITYILLCGFPPFRSENNLQEDLFDQILAGKLEF 611
           GT  ++APE++    YG   DVW+ G +   +    PP+ S +          +A  ++ 
Sbjct: 22  GTIAFMAPEVLRGESYGRACDVWSVGCVMIEMCTCRPPWNSHDISNHLALIFKIASSVD- 198

Query: 612 PAPYWDNITDSAKELISQMLQVNVEARCTAGEILSHP 648
           P P  +N++   ++L+ + L+ + + R +A ++L HP
Sbjct: 199 PPPIPENMSPPVRDLMLRCLEQDSDFRPSAKDLLMHP 309
>25019
          Length = 730

 Score = 45.8 bits (107), Expect = 6e-05,   Method: Composition-based stats.
 Identities = 27/63 (42%), Positives = 36/63 (57%), Gaps = 3/63 (4%)
 Frame = +3

Query: 518 ENLLVCEYPDGTKSLKLGDFGLAT-VVEGP--LYTVCGTPTYVAPEIIAETGYGLKVDVW 574
           EN+L+    D    +KL DFGL    + G    +T CGT  Y+APEI+  TG+G  VD W
Sbjct: 261 ENVLL----DKDGHVKLTDFGLCKEAITGTRVTHTFCGTIEYMAPEILTRTGHGKAVDWW 428

Query: 575 AAG 577
           + G
Sbjct: 429 SLG 437
>17722
          Length = 680

 Score = 45.4 bits (106), Expect = 7e-05,   Method: Compositional matrix adjust.
 Identities = 29/83 (34%), Positives = 43/83 (51%), Gaps = 5/83 (6%)
 Frame = -3

Query: 571 VDVWAAGVITYILLCGFPPFRSENNLQEDLFDQILAGKLEFPAPYWDNITDSAKELISQM 630
           VD W  GV+ Y ++CG  PF   N   + LF+ IL   ++FP     N+++ AK L+S +
Sbjct: 678 VDWWGTGVVMYEMMCGRLPFY--NRDHDVLFELILLQNVKFPR----NLSEEAKTLLSGL 517

Query: 631 LQVNVEARCTAG-----EILSHP 648
           L  N + R         EI +HP
Sbjct: 516 LAKNPKRRLGGSEADVTEIKTHP 448
>17253
          Length = 483

 Score = 45.4 bits (106), Expect = 8e-05,   Method: Composition-based stats.
 Identities = 33/137 (24%), Positives = 65/137 (47%), Gaps = 13/137 (9%)
 Frame = -1

Query: 420 ALKIIDKAKCCGKEHLIENEVSILRRV-KHPNIIMLVEEMETATDLFLVMELVKGGDLFD 478
           A+K  ++A    ++     E+SI+R++ +HPN++  +     +    ++ME    GDL  
Sbjct: 456 AVKTHNEAATDAEKSEFLRELSIMRKLPRHPNVVSFMGCCTMSDPALILMEFCCHGDLLS 277

Query: 479 AI------------TSSTKYTERDGSAMVYNLANALRYLHSLSIVHRDIKPENLLVCEYP 526
            +            +++   T RD  +   ++A  + ++ +  IVHRD+   N+L+ E  
Sbjct: 276 FLRKRRPDRTVFLTSTANDLTARDFFSFALHVARGMAHVANNKIVHRDVAARNVLISE-- 103

Query: 527 DGTKSLKLGDFGLATVV 543
                 K+ DFGL+  V
Sbjct: 102 --RNVCKVSDFGLSRRV 58
>11404
          Length = 563

 Score = 45.4 bits (106), Expect = 9e-05,   Method: Compositional matrix adjust.
 Identities = 41/141 (29%), Positives = 69/141 (48%), Gaps = 8/141 (5%)
 Frame = +1

Query: 391 EKYRIGKVIGDGNFAVVKECVDRYTGKEFALKIIDKAKCCGKEHLIENEV-SILRRVKHP 449
           ++Y I  +IG G+F  V +  D    ++ A+KII   K    +  IE ++  ++ R    
Sbjct: 139 DRYEIDSLIGKGSFGQVVKAYDHTDNEQVAIKIIKNKKPFLNQAQIEVKLLEMMNRHDTD 318

Query: 450 N---IIMLVEEMETATDLFLVMELVKGGDLFDAI--TSSTKYTERDGSAMVYNLANALRY 504
           N   I+ L       + L LV EL+   +L+D +  T+    +          L  AL +
Sbjct: 319 NKYYIVRLKRHFMFRSHLCLVFELL-SYNLYDLLRNTNFRGVSLNLTRKFAQQLCTALLF 495

Query: 505 LHS--LSIVHRDIKPENLLVC 523
           L +  +SI+H D+KPEN+L+C
Sbjct: 496 LATPEMSIIHCDLKPENILLC 558
>29590
          Length = 320

 Score = 45.1 bits (105), Expect = 1e-04,   Method: Composition-based stats.
 Identities = 23/85 (27%), Positives = 40/85 (47%), Gaps = 13/85 (15%)
 Frame = +3

Query: 550 VCGTPTYVAPEIIAETGYGLKVDVWAAGVITYILLCGFPPF-------RSENNLQEDLFD 602
           + GTP YVAPE++      ++ D+W+ GV++Y++L    PF        S  +L+ +   
Sbjct: 54  IIGTPDYVAPEVLDYEPLSIQTDMWSLGVLSYVMLTACSPFVGITSKKHSATSLRSNWTS 233

Query: 603 QILAGKLEFPAP------YWDNITD 621
           Q+++       P      YW    D
Sbjct: 234 QMISSLTSVLMPKTSSRNYWSKTPD 308
>21418
          Length = 831

 Score = 43.9 bits (102), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 25/95 (26%), Positives = 46/95 (48%), Gaps = 1/95 (1%)
 Frame = +2

Query: 603 QILAGKLEFPAPYWDNITDSAKELISQMLQVNVEARCTAGEILSHPWVSD-DASQENNMQ 661
           +I +G+ +FP P W N++ +AK+LI  ML V+   R    ++L + W++  DA  +  + 
Sbjct: 11  RIRSGQYDFPDPEWTNVSQAAKDLIKGMLNVDPSKRLCIEDVLRNKWIAQYDAVPQTPL- 187

Query: 662 AEVTGKLKQHFNNALPKQNSTTTGVSVIMNTALDK 696
              TG++ +      P+     T     M    D+
Sbjct: 188 --CTGRILKEGEETWPEVQEEMTRSLATMRVDYDQ 286
>04138
          Length = 800

 Score = 43.1 bits (100), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 31/85 (36%), Positives = 41/85 (48%), Gaps = 7/85 (8%)
 Frame = +1

Query: 502 LRYLHSLSIVHRDIKPENLLVCEYPDGTKSLKLGDFGLATVVEGPL-----YT-VCGTPT 555
           L Y+H   I+HRD+K  N+L+ +       LKL DFGLA      L     YT    T  
Sbjct: 52  LYYIHRNKILHRDMKAANILITK----QGVLKLADFGLARAFSVNLRQPNRYTNRVVTLW 219

Query: 556 YVAPE-IIAETGYGLKVDVWAAGVI 579
           Y  PE ++ +  Y   +D W AG I
Sbjct: 220 YRPPELLLGDRNYSTAIDQWGAGCI 294
>31120
          Length = 439

 Score = 42.7 bits (99), Expect = 5e-04,   Method: Composition-based stats.
 Identities = 29/92 (31%), Positives = 49/92 (53%), Gaps = 1/92 (1%)
 Frame = +1

Query: 560 EIIAETGYGLKV-DVWAAGVITYILLCGFPPFRSENNLQEDLFDQILAGKLEFPAPYWDN 618
           E++    Y  K+ D W+ GVI +I+L G  PF  ++NL + L DQ  + K  F     D 
Sbjct: 1   EVVCGVPYDPKMADAWSLGVILFIMLNGKMPF-DDSNLNKLLEDQ-RSKKYSFRRKLQDL 174

Query: 619 ITDSAKELISQMLQVNVEARCTAGEILSHPWV 650
           ++ +A+  +S +L+ N   R    E+L+  W+
Sbjct: 175 VSPNARSTVSVLLEPNSAMRWDLNEVLNCQWL 270
>00715
          Length = 1788

 Score = 42.7 bits (99), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 33/116 (28%), Positives = 51/116 (43%), Gaps = 27/116 (23%)
 Frame = +1

Query: 493 AMVYNLANALRYLHSLSIVHRDIKPENLLVCEYPDGTKSLKL--GDFGLA---------- 540
           ++   +A  L YLHS++IVH D+KP N L+      T+ LKL   DFG            
Sbjct: 250 SLALQMARGLHYLHSINIVHLDLKPANCLL------TRDLKLRIADFGCCHQLTPTGLDM 411

Query: 541 --------------TVVEGPLYT-VCGTPTYVAPEIIAETGYGLKVDVWAAGVITY 581
                         T V+G     + GT  Y APE++      ++ DV++ G+  +
Sbjct: 412 GEREGGMAGNELELTPVQGAWKNELAGTLAYRAPELLKGLQPSVRSDVYSLGITLW 579
>18401
          Length = 463

 Score = 42.7 bits (99), Expect = 6e-04,   Method: Composition-based stats.
 Identities = 20/63 (31%), Positives = 33/63 (52%)
 Frame = -3

Query: 549 TVCGTPTYVAPEIIAETGYGLKVDVWAAGVITYILLCGFPPFRSENNLQEDLFDQILAGK 608
           T+  T  Y APE+I E G+    DVW+ G I + L  G+  F++ +N +     + + G 
Sbjct: 455 TIVSTRHYRAPEVILELGWSHPCDVWSVGCIMFELYTGYTLFQTHDNKEHLAMMERILGS 276

Query: 609 LEF 611
           L +
Sbjct: 275 LPY 267
>36481
          Length = 806

 Score = 42.7 bits (99), Expect = 6e-04,   Method: Compositional matrix adjust.
 Identities = 37/135 (27%), Positives = 62/135 (45%), Gaps = 10/135 (7%)
 Frame = +2

Query: 400 GDGNFAVVKECVDRYTGKEFALKII---DKAKCCGKEHLIENEVSILRRV--KHPNIIML 454
           G+G F  V +C D   G + ALKII   DK +   K      E+++L ++  K P+   +
Sbjct: 389 GEGTFGKVVQCKDLLKGDDIALKIIKNVDKYREAAKL-----EINVLEKLREKDPHAKHM 553

Query: 455 VEEMETATDL---FLVMELVKGGDLFDAITSST--KYTERDGSAMVYNLANALRYLHSLS 509
             +M    D      +   + G  +FD +  ++   Y       + Y L  A+ +LH   
Sbjct: 554 CVQMLDWFDYHGHVCISFHMLGLSVFDFLKDNSYGAYPIEQVRHISYQLCYAVNFLHENQ 733

Query: 510 IVHRDIKPENLLVCE 524
           + H D+KPEN+L  +
Sbjct: 734 LTHTDLKPENILFVD 778
>32359
          Length = 928

 Score = 32.3 bits (72), Expect(2) = 8e-04,   Method: Compositional matrix adjust.
 Identities = 31/139 (22%), Positives = 62/139 (44%), Gaps = 20/139 (14%)
 Frame = -1

Query: 393 YRIGKVIGDGNFAVVKECVDRYTGKEFALKIIDKAKCCGKEHLIEN------EVSILRRV 446
           Y   KVIG+G+F VV           +  K++D ++    + ++++      E+ I+R++
Sbjct: 424 YTDAKVIGNGSFGVV-----------YQAKLVDTSELVAIKKVLQDKRFKNRELQIMRKL 278

Query: 447 KHPNIIML----VEEMETATDLF--LVMELVKGGDLFDAITSSTKYTERDGSAM------ 494
           +H NI+ L        E   ++F  LV+E V      + +    ++  +    +      
Sbjct: 277 EHQNIVKLKFFFYSSGEKKDEVFLNLVLEYVP-----ETVYRVARHYSKSKQTIPILYIK 113

Query: 495 --VYNLANALRYLHSLSIV 511
             +Y L  +L Y+HS + V
Sbjct: 112 LYMYQLFRSLAYIHSQACV 56

 Score = 28.5 bits (62), Expect(2) = 8e-04,   Method: Composition-based stats.
 Identities = 12/19 (63%), Positives = 16/19 (84%), Gaps = 1/19 (5%)
 Frame = -3

Query: 505 LHSLS-IVHRDIKPENLLV 522
           LH L+ + HRDIKP+NLL+
Sbjct: 80  LHPLTGVCHRDIKPQNLLL 24
>26009
          Length = 886

 Score = 42.0 bits (97), Expect = 8e-04,   Method: Compositional matrix adjust.
 Identities = 16/34 (47%), Positives = 26/34 (76%)
 Frame = +3

Query: 489 RDGSAMVYNLANALRYLHSLSIVHRDIKPENLLV 522
           R+  +++  L +AL ++HS  +VHRDIKPEN+L+
Sbjct: 711 REAKSVMKQLVSALDFMHSKQLVHRDIKPENVLI 812

 Score = 39.3 bits (90), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 47/170 (27%), Positives = 66/170 (38%), Gaps = 9/170 (5%)
 Frame = +2

Query: 386 SFPLLEKYRIGKVIGDGNFAVVKECVDRYTGKEFALKIIDKAKCCGKEHLIENEVSILRR 445
           +  L E Y + K +G G +  V     R+TG + ALK++ K+    +E   E ++S    
Sbjct: 401 TLSLREHYDVCKELGRGTYGKVVLARCRHTGTQVALKLLPKSCTKLREFQREFQLSYFLS 580

Query: 446 VKHPNIIMLVE-EMETATDLFLVMELVKGGDLFDAITSSTKYTERDGSAMVYNLANALRY 504
             H NII       +T +      E    GDLFDAI       E  G  + +  A     
Sbjct: 581 -PHANIIDTYNVAFQTRSSYVFAQEHAVLGDLFDAIPPQQGMRESRGQ-IRHETARVRAR 754

Query: 505 LHSLSIV--------HRDIKPENLLVCEYPDGTKSLKLGDFGLATVVEGP 546
           LH+   V         R      L  CE         L DFG+ T  +GP
Sbjct: 755 LHAQQAVSPS*HQARERAYPHAGLFPCE---------LMDFGM-TRKQGP 874
>20655
          Length = 1181

 Score = 42.0 bits (97), Expect = 9e-04,   Method: Compositional matrix adjust.
 Identities = 17/51 (33%), Positives = 30/51 (58%)
 Frame = +2

Query: 603 QILAGKLEFPAPYWDNITDSAKELISQMLQVNVEARCTAGEILSHPWVSDD 653
           +I  G+ EFP P W  ++  AK+LI  ML  + + R    ++++  WV+D+
Sbjct: 11  RIRNGQYEFPKPEWSRVSQDAKDLIRGMLCTDPDKRLNIKQVMASKWVADN 163
>17300
          Length = 480

 Score = 42.0 bits (97), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 31/106 (29%), Positives = 51/106 (48%), Gaps = 8/106 (7%)
 Frame = +1

Query: 498 LANALRYLHSLSIVHRDIKPENLLVCEYPDGTKSLKLGDFGLATVVEG----PLYTVCGT 553
           +++ +  L  +  VHRD+   N+LV E        K+ DFGL+  +E       YT  G 
Sbjct: 1   ISSGMGXLADMGYVHRDLAARNILVNE----ILVCKVADFGLSREIESDTTEGAYTTKGG 168

Query: 554 PT---YVAPEIIAETGYGLKVDVWAAGVITY-ILLCGFPPFRSENN 595
                + APE IA   +    DVW+ GV+ + ++  G  P+ + +N
Sbjct: 169 KIPVRWTAPEAIAYRKFTSASDVWSFGVVMWEVMSYGERPYWNWSN 306
>24241
          Length = 413

 Score = 40.0 bits (92), Expect = 0.004,   Method: Composition-based stats.
 Identities = 26/83 (31%), Positives = 48/83 (57%), Gaps = 5/83 (6%)
 Frame = -2

Query: 394 RIGKVIGDGNFAVVKECVDRYTGKEFALKIIDKAKCCGKEHLIEN----EVSILRRVKHP 449
           R+ K IG+G + VV +C  R TG++ A+K   K +  G E  + +    E+++LR ++H 
Sbjct: 331 RLSK-IGEGTYGVVYKCRHRATGRKLAMK---KIRLRGSEDGVPSSAIREIAMLRELRHT 164

Query: 450 NIIMLVEEMETATD-LFLVMELV 471
             ++ +E++    + LFLV E +
Sbjct: 163 QXLVCLEDVIMEDERLFLVFEFL 95
>37602
          Length = 804

 Score = 40.0 bits (92), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 25/74 (33%), Positives = 35/74 (47%)
 Frame = -1

Query: 464 LFLVMELVKGGDLFDAITSSTKYTERDGSAMVYNLANALRYLHSLSIVHRDIKPENLLVC 523
           L++ ME   GG + D    +   TE   + +       L YLH    +HRDIK  N+L+ 
Sbjct: 294 LWIAMEYCGGGSMQDIYHVTGPLTEPQIAFVCRETLKGLHYLHRRGKMHRDIKGANILLT 115

Query: 524 EYPDGTKSLKLGDF 537
           E  D    +KL DF
Sbjct: 114 EEGD----VKLADF 85
>27274
          Length = 396

 Score = 39.3 bits (90), Expect = 0.006,   Method: Composition-based stats.
 Identities = 24/100 (24%), Positives = 48/100 (48%), Gaps = 8/100 (8%)
 Frame = -1

Query: 560 EIIAETGYGLKVDVWAAGVITYILLCGFPPFRSENNLQE------DLFDQILAGKLEFPA 613
           E++    +G  VD+W+ G++ + LL G  PF  E   ++       ++ QI+ G      
Sbjct: 375 ELLRGQQHGPTVDMWSLGILLHELLSGHVPFEPERGSRQMARNMMAVYAQIIRGS---SR 205

Query: 614 PYWDNITDS--AKELISQMLQVNVEARCTAGEILSHPWVS 651
              D +  S    + + +++Q+    R T+ +  SHPW++
Sbjct: 204 DVCDGLALSTHGADFLRRLVQLEDTKRLTSQQAFSHPWIA 85
>16708
          Length = 1397

 Score = 38.5 bits (88), Expect = 0.011,   Method: Compositional matrix adjust.
 Identities = 26/67 (38%), Positives = 36/67 (53%), Gaps = 4/67 (5%)
 Frame = -1

Query: 493  AMVYNLAN----ALRYLHSLSIVHRDIKPENLLVCEYPDGTKSLKLGDFGLATVVEGPLY 548
            AMV  +A     AL ++H L +VH D+K +N+LV    D   + KL D+G+A      LY
Sbjct: 1094 AMVCCIAGQXVCALEHIHELGVVHMDVKADNVLV----DAHGNCKLTDYGIAQ-----LY 942

Query: 549  TVCGTPT 555
             V   PT
Sbjct: 941  KVYPAPT 921
>32957
          Length = 645

 Score = 38.1 bits (87), Expect = 0.012,   Method: Composition-based stats.
 Identities = 17/40 (42%), Positives = 23/40 (57%)
 Frame = +3

Query: 545 GPLYTVCGTPTYVAPEIIAETGYGLKVDVWAAGVITYILL 584
           G   T CGT  Y+APE+     YG +VD W  G++ + LL
Sbjct: 30  GRTRTFCGTREYMAPEVHERKEYGKEVDWWGLGILLHELL 149
>17982
          Length = 477

 Score = 37.7 bits (86), Expect = 0.018,   Method: Compositional matrix adjust.
 Identities = 28/95 (29%), Positives = 45/95 (47%), Gaps = 9/95 (9%)
 Frame = -1

Query: 391 EKYRIGKVIGDGNFAVVKECVDRYTGKEFALKIIDKAKCCGKEHLIENEVSILRRVK-HP 449
           +K R+ ++I +G FA V    D  +GK++ALK +  A        I +E+  L+++  HP
Sbjct: 285 QKLRVKRLIAEGGFAFVFVAQDVNSGKDYALKRL-LANDEENSKAIMDEIKYLKKLSGHP 109

Query: 450 NIIMLVEEMETATD--------LFLVMELVKGGDL 476
           +II  +       D          L+ EL  GG L
Sbjct: 108 HIIQFITAASIGKDQSDHGQSEFLLLTELCSGGQL 4
>17516
          Length = 453

 Score = 37.0 bits (84), Expect = 0.029,   Method: Composition-based stats.
 Identities = 16/39 (41%), Positives = 26/39 (66%), Gaps = 1/39 (2%)
 Frame = -3

Query: 549 TVCGTPTYVAPEIIAETG-YGLKVDVWAAGVITYILLCG 586
           T+ GTP Y+APE++ + G Y +K DV++  +I + L  G
Sbjct: 442 TLAGTPVYMAPEVLLQKGQYDMKADVYSLAIILWELWYG 326
>00638
          Length = 1595

 Score = 37.0 bits (84), Expect = 0.031,   Method: Compositional matrix adjust.
 Identities = 16/37 (43%), Positives = 23/37 (62%)
 Frame = +2

Query: 486 YTERDGSAMVYNLANALRYLHSLSIVHRDIKPENLLV 522
           +T+ D    +Y L  AL + HS+ I+HRD+KP   LV
Sbjct: 407 FTDYDIRFYLYELMKALDFCHSMGIMHRDVKPSPPLV 517
>21210
          Length = 518

 Score = 36.6 bits (83), Expect = 0.039,   Method: Compositional matrix adjust.
 Identities = 30/121 (24%), Positives = 57/121 (47%), Gaps = 4/121 (3%)
 Frame = +3

Query: 552 GTPTYVAPEII----AETGYGLKVDVWAAGVITYILLCGFPPFRSENNLQEDLFDQILAG 607
           G   Y+APE I    +  GY ++ DVW+ G+    L  G  P+R   ++ + L  Q++ G
Sbjct: 6   GCRPYMAPERIDPRASSHGYDVRSDVWSLGITLMELATGRFPYRKWVSIFDQL-QQVVRG 182

Query: 608 KLEFPAPYWDNITDSAKELISQMLQVNVEARCTAGEILSHPWVSDDASQENNMQAEVTGK 667
            +    P+    +      +++ L  + + R    ++L+HP+V     QE ++ + V   
Sbjct: 183 -VAPCLPHDGAFSHDFVNFVNKCLTKDEKQRPKYNKLLAHPFVRLYEEQEVDVASYVCNV 359

Query: 668 L 668
           L
Sbjct: 360 L 362
>29360
          Length = 363

 Score = 36.2 bits (82), Expect = 0.046,   Method: Composition-based stats.
 Identities = 32/125 (25%), Positives = 58/125 (46%), Gaps = 11/125 (8%)
 Frame = +3

Query: 409 ECVDRYTGKEFALKIIDKAKCCGKEHLIENEVSILRRVKHP-----NIIMLVEEMETATD 463
           +C  + T +  A+KI+       ++  IE  VSIL+R+        N +   E  +    
Sbjct: 6   KCWKKGTSEIVAIKILKNHPSYARQGQIE--VSILQRLSQESADDYNFVRAFECFQHKNH 179

Query: 464 LFLVMELVKGGDLFDAITSST------KYTERDGSAMVYNLANALRYLHSLSIVHRDIKP 517
             LV E+++  +L+D +  +       KY       +   +  ALR L  L ++H D+KP
Sbjct: 180 TCLVFEMLEQ-NLYDFLKQNKFQPLPLKYIR----PITQQVLTALRKLKQLGLIHADLKP 344

Query: 518 ENLLV 522
           EN+++
Sbjct: 345 ENIML 359
>33586
          Length = 551

 Score = 35.4 bits (80), Expect = 0.092,   Method: Composition-based stats.
 Identities = 14/40 (35%), Positives = 24/40 (60%)
 Frame = +2

Query: 451 IIMLVEEMETATDLFLVMELVKGGDLFDAITSSTKYTERD 490
           I+ L    +T   L+L++E ++GGDLF  ++    +TE D
Sbjct: 407 IVHLHYAFQTEGKLYLILEFLRGGDLFTRLSKEVMFTEED 526
>18481
          Length = 437

 Score = 35.0 bits (79), Expect = 0.11,   Method: Composition-based stats.
 Identities = 30/112 (26%), Positives = 53/112 (47%), Gaps = 5/112 (4%)
 Frame = -1

Query: 416 GKEFALKI--IDKAKCCGKEHLIENEVSILRRV-KHPNIIMLVEEMETATDLFLVMELVK 472
           GK+ A+KI  ID      K  L+  E  +  ++ +HP +  +           LVMEL+ 
Sbjct: 410 GKDIAVKIEAIDV-----KHQLLHYEAKVYEQIGRHPGLPTMYHYGTEKHFNALVMELLG 246

Query: 473 GG--DLFDAITSSTKYTERDGSAMVYNLANALRYLHSLSIVHRDIKPENLLV 522
               +LF  +    ++T +    +   L + L ++H    +HRD+KP+N L+
Sbjct: 245 PSLEELF--VICKRRFTLKTILMVSDQLLSRLEFIHQKCFIHRDLKPDNFLM 96
>07836
          Length = 1478

 Score = 35.0 bits (79), Expect = 0.12,   Method: Compositional matrix adjust.
 Identities = 40/145 (27%), Positives = 66/145 (45%), Gaps = 19/145 (13%)
 Frame = -1

Query: 437  ENEVSILRRVKHPNIIMLV----EEMETATDLFLVMELVKGGDLFDAITSSTKYTERDGS 492
            E E+     ++H NI+  +    +   + T LFL+ +  + G L D + S       +  
Sbjct: 1421 ETELYQTVLLRHENILGFIAADIKGTGSWTQLFLITDYHENGSLHDYLLSRV-LDSSEML 1245

Query: 493  AMVYNLANALRYLH--------SLSIVHRDIKPENLLVCEYPDGTKSLKLGDFGLAT--V 542
            A+ ++    L +LH          +I HRDIK +N+LV +  +GT    + D GLA   +
Sbjct: 1244 ALAHSAICGLAHLHIEIFGTRGKPAIAHRDIKSKNILVKK--NGTCC--IADLGLAVRYI 1077

Query: 543  VEGPLYTVC-----GTPTYVAPEII 562
             E     V      GT  Y+APE++
Sbjct: 1076 SESNEVDVAPNPRQGTKRYMAPEVL 1002
>21800
          Length = 855

 Score = 34.7 bits (78), Expect = 0.13,   Method: Compositional matrix adjust.
 Identities = 16/45 (35%), Positives = 27/45 (60%), Gaps = 1/45 (2%)
 Frame = +2

Query: 494 MVYNLANALRYLHS-LSIVHRDIKPENLLVCEYPDGTKSLKLGDF 537
           ++  +   L YLH+  +I+H DIKPEN+L+C   +  + L +  F
Sbjct: 647 IIRQVLEGLNYLHAKCNIIHTDIKPENILICVDDNYIRKLAVDAF 781
>22005
          Length = 873

 Score = 33.1 bits (74), Expect = 0.42,   Method: Compositional matrix adjust.
 Identities = 43/199 (21%), Positives = 68/199 (34%), Gaps = 50/199 (25%)
 Frame = +1

Query: 436 IENEVSILRRVKHPNIIMLVEEMETATDLFLVMELVKGGDLFDAI--------------- 480
            E E S++    HPNI+ L+        + L+ E +  GDL D +               
Sbjct: 151 FEREASLMADFDHPNIVKLLGVCAIGKPMCLLFEFMSKGDLNDFLRLCSPENYNLPVSRS 330

Query: 481 --------------------TSSTKYTERDGSAMVY---------NLANALRYLHSLSIV 511
                                  T+  +RD S M+           ++  + YL     V
Sbjct: 331 QNLVVDLEDGLRVEVEAEECEKDTQSEDRDCSGMLXTKDQLYISQQISAGMAYLAQKDYV 510

Query: 512 HRDIKPENLLVCEYPDGTKSLKLGDFGLATVVEGPLYTVCGTPTYVAP------EIIAET 565
           HRD+    +        T    + DFGLA  V    Y   G+     P      E I  +
Sbjct: 511 HRDLATRTVXS-----RTT*S*ISDFGLARSVHSVDYYR-GSEQDAIPIRWMPLEAILYS 672

Query: 566 GYGLKVDVWAAGVITYILL 584
            +  + DVW+ GV+ + +L
Sbjct: 673 KFSTQSDVWSFGVVLWEIL 729
>00394
          Length = 548

 Score = 33.1 bits (74), Expect = 0.44,   Method: Compositional matrix adjust.
 Identities = 24/89 (26%), Positives = 40/89 (44%), Gaps = 6/89 (6%)
 Frame = -2

Query: 394 RIGKVIGDGNFAVVKECVDRYTGKEFAL-KIIDKAKCCGKEHLIENEVSILRRVKHPNII 452
           +  K IG G+F  V + +D   G   A  ++ DK     +    + E  +L+ ++HPNI+
Sbjct: 289 KFDKEIGRGSFKTVYKGLDTELGVAVAWCELQDKKWNKAERQRFKEEAEMLKELQHPNIV 110

Query: 453 MLVEEMETATD-----LFLVMELVKGGDL 476
              +  E         + LV EL+  G L
Sbjct: 109 RFFDYWEEHNHRNRKVIILVTELMTSGTL 23
>31789
          Length = 676

 Score = 32.0 bits (71), Expect = 0.94,   Method: Compositional matrix adjust.
 Identities = 23/84 (27%), Positives = 38/84 (45%), Gaps = 6/84 (7%)
 Frame = +2

Query: 399 IGDGNFAVVKECVDRYTGKEFAL-KIIDKAKCCGKEHLIENEVSILRRVKHPNIIMLVEE 457
           IG G+F  V + +D   G   A  ++ DK     +    + E  +L+ ++HPNI+   + 
Sbjct: 344 IGRGSFKTVYKGLDTELGVAVAWCELQDKKWNKTERQRFKEEAEMLKELQHPNIVRFFDY 523

Query: 458 METATD-----LFLVMELVKGGDL 476
            E         + LV EL+  G L
Sbjct: 524 WEEHNHRNRKVIILVTELMTSGTL 595
>06854
          Length = 1901

 Score = 30.4 bits (67), Expect = 3.0,   Method: Compositional matrix adjust.
 Identities = 13/36 (36%), Positives = 23/36 (63%)
 Frame = +1

Query: 438  NEVSILRRVKHPNIIMLVEEMETATDLFLVMELVKG 473
             E S++++VKHP++ + VE  +  T LFL +  + G
Sbjct: 1318 TERSLVQQVKHPDVGLCVEGGQVQTQLFLDLRQLPG 1425
>16350
          Length = 1108

 Score = 30.0 bits (66), Expect = 3.7,   Method: Compositional matrix adjust.
 Identities = 30/118 (25%), Positives = 47/118 (39%), Gaps = 7/118 (5%)
 Frame = +2

Query: 514 DIKPE----NLLVCEYPDGTKSLKLGDFGLATVVEGPLYTVCGTPTYVAPEIIAETGYGL 569
           D KPE    N +  ++P     +K+ D G A            T  Y   E++   GYG 
Sbjct: 305 DNKPECDPVNEICTDFP-----VKIADLGNACWTYHHFTEDIQTRQYRCLEVLIGAGYGT 469

Query: 570 KVDVWAAGVITYILLCG---FPPFRSENNLQEDLFDQILAGKLEFPAPYWDNITDSAK 624
             D+W+   + + L  G   F P   E+  ++   +  LA  +E   P   +I  S K
Sbjct: 470 PADIWSTACMAFELATGDYLFEPHSGEDYSRD---EDHLAHVIELVGPIPRHIALSGK 634
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6678930|ref|NP_032650.1| muscle and microspikes RAS
[Mus musculus]
         (208 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

19046                                                                 164   3e-41
00858                                                                 162   8e-41
24619                                                                 160   4e-40
07580                                                                 154   7e-40
26536                                                                 108   2e-24
36482                                                                  95   2e-20
06994                                                                  67   2e-15
14456                                                                  77   5e-15
11257                                                                  72   1e-13
18509                                                                  65   5e-13
08428                                                                  70   7e-13
07465                                                                  69   1e-12
30760                                                                  67   4e-12
12339                                                                  65   2e-11
34468                                                                  64   3e-11
33794                                                                  64   4e-11
13745                                                                  62   1e-10
01972                                                                  62   2e-10
17511                                                                  61   3e-10
34359                                                                  59   1e-09
11728                                                                  59   2e-09
32723                                                                  56   1e-08
19656                                                                  54   6e-08
33374                                                                  51   3e-07
19006                                                                  50   9e-07
33380                                                                  47   4e-06
26083                                                                  45   3e-05
31291                                                                  41   3e-04
31928                                                                  39   0.001
35581                                                                  33   0.095
00552                                                                  32   0.13 
25655                                                                  28   2.3  
10708                                                                  28   2.8  
28114                                                                  27   7.4  
>19046
          Length = 445

 Score =  164 bits (414), Expect = 3e-41,   Method: Compositional matrix adjust.
 Identities = 78/110 (70%), Positives = 92/110 (83%)
 Frame = -2

Query: 71  QEEFSAMREQYMRTGDGFLIVYSVTDKASFEHVDRFHQLILRVKDRESFPMILVANKVDL 130
           QEEFSAMREQYMR GDGFL+V+SVTD  SFE++  FH  ILRVKDR+S+PMIL ANKVDL
Sbjct: 444 QEEFSAMREQYMRKGDGFLLVFSVTDFRSFENMANFHTQILRVKDRDSYPMILCANKVDL 265

Query: 131 MHLRKVTRDQGKEMATKYNIPYIETSAKDPPLNVDKTFHDLVRVIRQQVP 180
           +H RKV+ +Q +++AT+  IPYIETSAKDPPLNVD  FH +VRVIR Q P
Sbjct: 264 VHQRKVSEEQVRDLATRLRIPYIETSAKDPPLNVDLAFHQVVRVIRAQPP 115
>00858
          Length = 1658

 Score =  162 bits (410), Expect = 8e-41,   Method: Compositional matrix adjust.
 Identities = 87/165 (52%), Positives = 109/165 (66%)
 Frame = -2

Query: 11   LPTYKLXXXXXXXXXKSALTIQFFQKIFVPDYDPTIEDSYLKHTEIDNQWAILDVLDTAG 70
            +  YKL         KSALTIQ  Q  FV +YDPT EDS  K   ID +  +LD+LDTAG
Sbjct: 1597 MTEYKLVVVGAGGVGKSALTIQLXQNHFVEEYDPTXEDSXRKQVVIDGETCLLDILDTAG 1418

Query: 71   QEEFSAMREQYMRTGDGFLIVYSVTDKASFEHVDRFHQLILRVKDRESFPMILVANKVDL 130
            QEE SAMR+Q MRTG+GFL V++V +  SFE ++++ + I RVKD +  PM+LV NKVDL
Sbjct: 1417 QEEXSAMRDQCMRTGEGFLCVFAVXNLKSFEDINQYREQIKRVKDADEVPMVLVGNKVDL 1238

Query: 131  MHLRKVTRDQGKEMATKYNIPYIETSAKDPPLNVDKTFHDLVRVI 175
              +R V + QGK MA  Y+IPY+ETSAK     VD  F+ LVR I
Sbjct: 1237 -PIRNVEQRQGKHMAELYHIPYVETSAKTRQ-GVDDAFYTLVREI 1109
>24619
          Length = 509

 Score =  160 bits (405), Expect = 4e-40,   Method: Compositional matrix adjust.
 Identities = 76/110 (69%), Positives = 91/110 (82%)
 Frame = -2

Query: 71  QEEFSAMREQYMRTGDGFLIVYSVTDKASFEHVDRFHQLILRVKDRESFPMILVANKVDL 130
           QEEFSAMREQYMR GDGFL+V+SV D  SFE++  FH  ILRVKDR+++PMIL ANKVDL
Sbjct: 508 QEEFSAMREQYMRKGDGFLLVFSVIDYQSFENMVNFHTQILRVKDRDTYPMILCANKVDL 329

Query: 131 MHLRKVTRDQGKEMATKYNIPYIETSAKDPPLNVDKTFHDLVRVIRQQVP 180
           +H RKV+ +Q +++AT+  IPYIETSAKDPPLNVD  FH +VRVIR Q P
Sbjct: 328 VHQRKVSEEQVRDLATRLRIPYIETSAKDPPLNVDLAFHQVVRVIRAQPP 179
>07580
          Length = 921

 Score =  154 bits (388), Expect(2) = 7e-40,   Method: Compositional matrix adjust.
 Identities = 72/145 (49%), Positives = 101/145 (69%)
 Frame = +3

Query: 37  IFVPDYDPTIEDSYLKHTEIDNQWAILDVLDTAGQEEFSAMREQYMRTGDGFLIVYSVTD 96
           IFV  YDPTIEDSY K  E+D Q  +L++LDTAG E+F+AMR+ YM+ G GFL+ YS+T 
Sbjct: 132 IFVEKYDPTIEDSYRKQVEVDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFLLAYSITA 311

Query: 97  KASFEHVDRFHQLILRVKDRESFPMILVANKVDLMHLRKVTRDQGKEMATKYNIPYIETS 156
           +++F  +    + ILRVKD +  PM+LV NK DL   R V +DQG+ +A  ++  ++ETS
Sbjct: 312 QSTFNDLQELREQILRVKDTDDVPMLLVGNKCDLEDERVVGKDQGQGLARSFSCAFLETS 491

Query: 157 AKDPPLNVDKTFHDLVRVIRQQVPE 181
           AK   +NV++ F DLVR I ++ PE
Sbjct: 492 AK-ARINVNEIFMDLVRQINKKSPE 563

 Score = 26.9 bits (58), Expect(2) = 7e-40,   Method: Compositional matrix adjust.
 Identities = 13/33 (39%), Positives = 16/33 (48%)
 Frame = +2

Query: 8  SENLPTYKLXXXXXXXXXKSALTIQFFQKIFVP 40
          +E +  YKL         KSALT+QF Q  F  
Sbjct: 44 TETMREYKLVVLGSGGVGKSALTVQFVQGDFCG 142
>26536
          Length = 829

 Score =  108 bits (269), Expect = 2e-24,   Method: Compositional matrix adjust.
 Identities = 53/110 (48%), Positives = 73/110 (66%)
 Frame = +2

Query: 66  LDTAGQEEFSAMREQYMRTGDGFLIVYSVTDKASFEHVDRFHQLILRVKDRESFPMILVA 125
           LDTAGQEE+S+MRE Y R+GDGF++VYSVTD  SF+  +   + + R +D  S   +L  
Sbjct: 143 LDTAGQEEYSSMREHYTRSGDGFIVVYSVTDVTSFQEAEAVFRWLTRFQDETSIHAVLCG 322

Query: 126 NKVDLMHLRKVTRDQGKEMATKYNIPYIETSAKDPPLNVDKTFHDLVRVI 175
           NK DL   RKVT ++G++MA +  + Y ETSAK    NV + +H L+R I
Sbjct: 323 NKTDLTSDRKVTPEEGRKMADRLGMLYFETSAKTGD-NVSQVYHGLLRSI 469

 Score = 43.5 bits (101), Expect = 6e-05,   Method: Compositional matrix adjust.
 Identities = 21/46 (45%), Positives = 27/46 (58%)
 Frame = +2

Query: 14  YKLXXXXXXXXXKSALTIQFFQKIFVPDYDPTIEDSYLKHTEIDNQ 59
           YK+         KS+LTI+F Q  F+  YDPTIEDSY K  ++  Q
Sbjct: 488 YKIVMLGSGGVGKSSLTIRFTQDTFLDVYDPTIEDSYRKMIQVSGQ 625
>36482
          Length = 686

 Score = 94.7 bits (234), Expect = 2e-20,   Method: Compositional matrix adjust.
 Identities = 52/151 (34%), Positives = 85/151 (56%), Gaps = 2/151 (1%)
 Frame = +2

Query: 29  LTIQFFQKIFVPDYDPTIEDSYLKHTEIDNQWAILDVLDTAGQEEFSAMREQYMRTGDGF 88
           LT++F  + F+ +Y PT+E  Y  HT I++    L++LDTAGQ  +   +E Y    D F
Sbjct: 2   LTVRFLTRRFIGEYCPTLESVYKYHTVIEDDDVRLEILDTAGQGTY-PWKEGYALWADCF 178

Query: 89  LIVYSVTDKASFEHVDRFHQLILRVKDRESFPMILVANKVDLMHLRKVTRDQGKEMATKY 148
           + VYS+ D+ S+E + +  + +  V+   S   +L ANK DL+H R+VT+ +G+++A + 
Sbjct: 179 VFVYSINDRQSYEELVQVKRQVESVRKSTSLTAVLAANKTDLLHDRQVTQKEGEDLAEEI 358

Query: 149 NIPYIETSAKDPPL--NVDKTFHDLVRVIRQ 177
                E SA +      +   FHDL R  R+
Sbjct: 359 GCRLYEVSASEGSQMEAITSMFHDLYREFRK 451
>06994
          Length = 429

 Score = 66.6 bits (161), Expect(2) = 2e-15,   Method: Compositional matrix adjust.
 Identities = 34/91 (37%), Positives = 47/91 (51%), Gaps = 32/91 (35%)
 Frame = +1

Query: 42  YDPTIEDSYLKHTEIDNQWAILDVLDTAG------------------------------- 70
           YDPTIEDSY K  E+D Q  +L++LDTAG                               
Sbjct: 142 YDPTIEDSYRKQVEVDGQQCMLEILDTAGTVHASHSNACVHGSLHAFVGTVTPLGRDALL 321

Query: 71  -QEEFSAMREQYMRTGDGFLIVYSVTDKASF 100
             E+F+AMR+ YM+ G GFL+ YS+T +++F
Sbjct: 322 NTEQFTAMRDLYMKNGQGFLLAYSITAQSTF 414

 Score = 32.0 bits (71), Expect(2) = 2e-15,   Method: Compositional matrix adjust.
 Identities = 15/32 (46%), Positives = 18/32 (56%)
 Frame = +3

Query: 8  SENLPTYKLXXXXXXXXXKSALTIQFFQKIFV 39
          +E +  YKL         KSALT+QF Q IFV
Sbjct: 39 TETMREYKLVVLGSGGVGKSALTVQFVQGIFV 134
>14456
          Length = 1867

 Score = 77.0 bits (188), Expect = 5e-15,   Method: Compositional matrix adjust.
 Identities = 51/157 (32%), Positives = 84/157 (53%), Gaps = 5/157 (3%)
 Frame = -1

Query: 26   KSALTIQFFQKIFVPDYDPTIEDSYL-KHTEIDNQWAILDVLDTAGQEEFSAMREQYMRT 84
            KS+L  +F    F      TI   +L K   +D++   + + DTAGQE F ++R  + R 
Sbjct: 1102 KSSLMNRFVSNKFDAQSFHTIGVEFLNKDVVVDDETYTMQIWDTAGQERFKSLRTPFYRG 923

Query: 85   GDGFLIVYSVTDKASFEHVDRFHQLILR---VKDRESFPMILVANKVDLMHLRKVTRDQG 141
             D  L+ +SV    SF ++  + +  L    ++D  +FP +++ NK+D+   R+VT ++ 
Sbjct: 922  ADCCLLTFSVDSMQSFRNLSMWRKEFLYYADIQDGVTFPFVVLGNKIDV-EGRQVTNEEA 746

Query: 142  KEMAT-KYNIPYIETSAKDPPLNVDKTFHDLVRVIRQ 177
            +   T   N PY ETSAKD   NV+K F   V+ +R+
Sbjct: 745  RSWCTANSNAPYFETSAKDAT-NVEKAFLAAVQRLRE 638
>11257
          Length = 1102

 Score = 72.4 bits (176), Expect = 1e-13,   Method: Compositional matrix adjust.
 Identities = 40/129 (31%), Positives = 68/129 (52%), Gaps = 3/129 (2%)
 Frame = -2

Query: 52   KHTEIDNQWAILDVLDTAGQEEFSAMREQYMRTGDGFLIVYSVTDKASFEHVDRFHQLIL 111
            K   +D +   + + DTAGQE + ++R  + R  D  L+ +SV +  S + +  ++   +
Sbjct: 1053 KDVVVDGETFTMQIWDTAGQERYKSLRTPFYRGTDCCLLTFSVDNLKSLQSLSDWYDEFV 874

Query: 112  R---VKDRESFPMILVANKVDLMHLRKVTRDQGKEMATKYNIPYIETSAKDPPLNVDKTF 168
                ++D  SFP +++ NK D+      + D      T  N+PY ETSAKD  LNV + F
Sbjct: 873  NYADIQDSASFPFVIIGNKADIEEREVSSEDAYNWCRTHGNLPYFETSAKD-SLNVQQAF 697

Query: 169  HDLVRVIRQ 177
              +VR +R+
Sbjct: 696  LAVVRRLRE 670
>18509
          Length = 625

 Score = 64.7 bits (156), Expect(2) = 5e-13,   Method: Compositional matrix adjust.
 Identities = 37/66 (56%), Positives = 45/66 (68%)
 Frame = -3

Query: 112 RVKDRESFPMILVANKVDLMHLRKVTRDQGKEMATKYNIPYIETSAKDPPLNVDKTFHDL 171
           RVKD +  PM+LV NKVDL  +R V + QGK MA  Y+IPY+ETSAK     VD  F+ L
Sbjct: 548 RVKDADEVPMVLVGNKVDL-PIRNVEQRQGKHMAELYHIPYVETSAKTRQ-GVDDAFYTL 375

Query: 172 VRVIRQ 177
           VR IR+
Sbjct: 374 VREIRK 357

 Score = 25.8 bits (55), Expect(2) = 5e-13,   Method: Compositional matrix adjust.
 Identities = 9/25 (36%), Positives = 18/25 (72%)
 Frame = -1

Query: 86  DGFLIVYSVTDKASFEHVDRFHQLI 110
           +GFL V++V +  SFE ++++ + I
Sbjct: 625 EGFLCVFAVNNLKSFEDINQYREQI 551
>08428
          Length = 1109

 Score = 70.1 bits (170), Expect = 7e-13,   Method: Compositional matrix adjust.
 Identities = 47/149 (31%), Positives = 75/149 (50%), Gaps = 1/149 (0%)
 Frame = -3

Query: 26   KSALTIQFFQKIFVPDYDPTIEDSYL-KHTEIDNQWAILDVLDTAGQEEFSAMREQYMRT 84
            KS++ ++F    + P  + TI  S++ K   +D       + DTAGQE+F A+   Y R 
Sbjct: 1032 KSSIVLRFVTGSYRPSQESTIGASFMSKSLVVDGAGYRFQIWDTAGQEKFRALAPMYYRG 853

Query: 85   GDGFLIVYSVTDKASFEHVDRFHQLILRVKDRESFPMILVANKVDLMHLRKVTRDQGKEM 144
                +IVY VT   +F+ V  + Q  LR     +  + +  NK DL  LR+V     +E 
Sbjct: 852  AAAAVIVYDVTRPRTFKSVKSWIQE-LRSFGPPNIVLAIAGNKCDLEELREVVEKDAQEY 676

Query: 145  ATKYNIPYIETSAKDPPLNVDKTFHDLVR 173
            A+  +  + ETSA    +NV++ F +L R
Sbjct: 675  ASSISAIFGETSAMT-AVNVEEMFTELAR 592
>07465
          Length = 1103

 Score = 68.9 bits (167), Expect = 1e-12,   Method: Compositional matrix adjust.
 Identities = 45/148 (30%), Positives = 80/148 (54%), Gaps = 2/148 (1%)
 Frame = +3

Query: 27  SALTIQFFQKIFVPDYDPTIEDSYL-KHTEIDNQWAILDVLDTAGQEEFSAMREQYMRTG 85
           S++  ++ + IF  DY  TI   +L +  E+  +   L + DTAGQEEF A+ + Y R  
Sbjct: 240 SSMIQRYCKGIFTKDYKKTIGVDFLERQIEVGGEDVRLMLWDTAGQEEFDAITKAYYRGA 419

Query: 86  DGFLIVYSVTDKASFEHVDRFHQLILRVKDR-ESFPMILVANKVDLMHLRKVTRDQGKEM 144
              ++ +S  D+ SFE ++ + +   +V+D      M++V NK+DL+    V  ++ + +
Sbjct: 420 QACVLAFSTVDRDSFEALETWKR---KVEDEVGEIGMVIVQNKIDLIDDAVVRPEEAENL 590

Query: 145 ATKYNIPYIETSAKDPPLNVDKTFHDLV 172
           A K  + +  TS K+  +NVD+ F  L 
Sbjct: 591 AKKLRLRFYRTSVKE-NMNVDEVFRYLA 671
>30760
          Length = 596

 Score = 67.4 bits (163), Expect = 4e-12,   Method: Compositional matrix adjust.
 Identities = 39/115 (33%), Positives = 60/115 (52%), Gaps = 6/115 (5%)
 Frame = -1

Query: 63  LDVLDTAGQEEFSAMREQYMRTGDGFLIVYSVTDKASFEHVDRFHQLILRVKDRESFPMI 122
           L + D+AG+E FS    ++       ++VY VTD+ SF    R+ + +   K     P +
Sbjct: 365 LYLFDSAGKEIFSENVTKFWDQPSVVMVVYDVTDETSFSGCVRWLERVRAAKPNTVIPGV 186

Query: 123 LVANKVDLMHLRKVTRDQGKEMATKYNIPYIETSAKD------PPLNVDKTFHDL 171
           LVANK DL   R+V+R +GK++A  + + Y E SAK+      P   +   FH L
Sbjct: 185 LVANKTDLDERRRVSRKEGKDLAQSHGLEYFECSAKEMQNTDTPFFCLAHAFHKL 21
>12339
          Length = 578

 Score = 65.1 bits (157), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 37/107 (34%), Positives = 63/107 (58%), Gaps = 4/107 (3%)
 Frame = -2

Query: 71  QEEFSAMREQYMRTGDGFLIVYSVTDKASFEHVDRFHQLILRV---KDRESFPMILVANK 127
           QE F ++   + R  D  ++VY VT+  +F+ +D + +  L     +D E FP +++ NK
Sbjct: 577 QERFQSLGVAFYRGADCCILVYDVTEXKTFDSLDSWQREFLNQASPRDPEHFPFVVIGNK 398

Query: 128 VDLMHLRKVTRDQGKE-MATKYNIPYIETSAKDPPLNVDKTFHDLVR 173
           +DL + R VT  +G+   +TK  IPY ETSAK+  +NV++ F  + +
Sbjct: 397 IDLDN-RVVTAKRGQGWCSTKGGIPYFETSAKE-AINVEQAFQTVAK 263
>34468
          Length = 1502

 Score = 64.3 bits (155), Expect = 3e-11,   Method: Compositional matrix adjust.
 Identities = 50/171 (29%), Positives = 81/171 (47%), Gaps = 4/171 (2%)
 Frame = +1

Query: 14  YKLXXXXXXXXXKSALTIQFFQKIFVPDYDPTIE-DSYLKHTEIDNQWAILDVLDTAGQE 72
           +K+         K+ LT +F    F    + TI  D   K  ++D++   L + DTAGQE
Sbjct: 496 FKIIVIGDSNVGKTCLTYRFCLGKFPDKTEATIGVDFREKSIQVDSEHLKLQLWDTAGQE 675

Query: 73  EF-SAMREQYMRTGDGFLIVYSVTDKASFEHVDRFHQLILRVKDRESFPMILVANKVDLM 131
            F  +M + Y R     + VY +T  +SFE++  + +   R    +  P ILV NK D++
Sbjct: 676 RFRKSMVQHYYRNVHAVVFVYDMTKMSSFENMPAWIEECDRHNLTKYIPRILVGNKCDVV 855

Query: 132 HLRKVTRDQGKEMATKYNIPYIETSAKD--PPLNVDKTFHDLVRVIRQQVP 180
               V  +  ++ A  +N+P  ETSAKD     +VD  F  +   ++   P
Sbjct: 856 ERIAVNTNLAQKFADAHNMPLFETSAKDDEKANHVDAIFMTVAHKLKXSKP 1008
>33794
          Length = 779

 Score = 64.3 bits (155), Expect = 4e-11,   Method: Compositional matrix adjust.
 Identities = 39/146 (26%), Positives = 70/146 (47%), Gaps = 3/146 (2%)
 Frame = -1

Query: 63  LDVLDTAGQEEFSAMREQYMRTGDGFLIVYSVTDKASFEHVDRFHQLILRVKDRESFPMI 122
           L + DT+GQ  F  +   Y R   G ++VY +T+K SF+ +DR+ + +   +     P +
Sbjct: 644 LQIWDTSGQGRFCTIIRSYSRGAQGIILVYDITNKWSFDGIDRWLKEV--EEHAPGIPKV 471

Query: 123 LVANKVDLMHLRKVTRDQGKEMATKYNIPYIETSAKDPPL---NVDKTFHDLVRVIRQQV 179
           LV N++ L + R+V   Q +  A++ N+   E S    PL   N+ ++F +L R+   + 
Sbjct: 470 LVGNRLHLAYKRQVAAKQAETYASRNNMSCFEIS----PLCDFNIRESFCELARMALHR- 306

Query: 180 PEXXXXXXXXXXWRGDRATGTHKLQC 205
                       WR ++     +L C
Sbjct: 305 ------NGMEHIWRSNKVLSLQELCC 246
>13745
          Length = 1045

 Score = 62.4 bits (150), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 38/114 (33%), Positives = 62/114 (54%), Gaps = 3/114 (2%)
 Frame = +2

Query: 71  QEEFSAMREQYMRTGDGFLIVYSVTDKASFEHVDRFHQLIL---RVKDRESFPMILVANK 127
           QE F ++   + R  D  ++VY VT   SF+++D +    L     +D E FP +++ NK
Sbjct: 2   QERFQSLGVAFYRGADCCVLVYDVTAPNSFKNLDSWRDEFLIQASPRDPEHFPFVVLGNK 181

Query: 128 VDLMHLRKVTRDQGKEMATKYNIPYIETSAKDPPLNVDKTFHDLVRVIRQQVPE 181
           VDL + +  TR   +   +K +IPY ETSAK+  +NV+  F  + +   +Q  E
Sbjct: 182 VDLDNRQVSTRRAQQWCQSKNDIPYYETSAKE-GINVEMAFQTIAKNALEQETE 340
>01972
          Length = 2359

 Score = 61.6 bits (148), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 39/111 (35%), Positives = 64/111 (57%)
 Frame = +3

Query: 63  LDVLDTAGQEEFSAMREQYMRTGDGFLIVYSVTDKASFEHVDRFHQLILRVKDRESFPMI 122
            +V DTAGQE+F  +R+ Y   G   +I++ VT + ++++V  +H+ ++RV   E+ P++
Sbjct: 453 FNVWDTAGQEKFGGLRDGYYIQGQCAVIMFDVTSRVTYKNVPNWHRDLVRV--CENIPIV 626

Query: 123 LVANKVDLMHLRKVTRDQGKEMATKYNIPYIETSAKDPPLNVDKTFHDLVR 173
           L  NKVD+   RKV + +      K N+ Y + SAK    N +K F  L R
Sbjct: 627 LCGNKVDIKD-RKV-KAKAIVFHRKKNLQYYDISAKS-NYNFEKPFLWLAR 770
>17511
          Length = 483

 Score = 60.8 bits (146), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 34/109 (31%), Positives = 58/109 (53%), Gaps = 4/109 (3%)
 Frame = -3

Query: 26  KSALTIQFFQKIFVPDYDPTIEDSYL-KHTEIDNQWAILDVLDTAGQEEFSAMREQYMRT 84
           K++L  Q+  K F   Y  TI   +L K   +D++   + + DTAGQE F ++   + R 
Sbjct: 328 KTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQIWDTAGQERFQSLGVAFYRG 149

Query: 85  GDGFLIVYSVTDKASFEHVDRFHQLIL---RVKDRESFPMILVANKVDL 130
            D  ++V+ VT   +F  +D +    L     +D E+FP +++ NK+DL
Sbjct: 148 ADCCVLVFDVTMPNTFRSLDSWRDEFLIQASPRDPENFPFVVIGNKIDL 2
>34359
          Length = 1042

 Score = 58.9 bits (141), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 28/101 (27%), Positives = 58/101 (57%), Gaps = 4/101 (3%)
 Frame = +3

Query: 63  LDVLDTAGQEEFSAMREQYMRTGDGFLIVYSVTDKASFEHVDRFHQLILRVKDRESFPMI 122
            +V DTAGQE+F  +R+ Y   G   +I++ VT + ++++V  +H+ ++RV   E+ P++
Sbjct: 201 FNVWDTAGQEKFGGLRDGYYIQGTCAIIMFDVTSRVTYKNVPNWHRDLVRVC--ENIPIV 374

Query: 123 LVANKVDL----MHLRKVTRDQGKEMATKYNIPYIETSAKD 159
           L  NKVD+    +  + +   + +  +T  ++P   T+ + 
Sbjct: 375 LCGNKVDIKDRKVKAKAIVFHRKRTCSTTTSVPRATTTLRS 497
>11728
          Length = 635

 Score = 58.9 bits (141), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 45/146 (30%), Positives = 70/146 (47%), Gaps = 14/146 (9%)
 Frame = -1

Query: 26  KSALTIQFFQKIFVPDYDPTIEDSYLKHTEIDNQWAILDVLDTAGQEEFSAMREQYMRTG 85
           K+ L I +    F  +Y PT+ D+Y  +  +D++   L + DTAGQE++  +R       
Sbjct: 452 KTCLLISYTTNAFPGEYIPTVFDNYSANVMVDSKPINLGLWDTAGQEDYDRLRPLSYPQT 273

Query: 86  DGFLIVYSVTDKASFEHVD-RFHQLILRVKDRESFPMILVANKVDLMH------------ 132
           D FLI +S+   ASFE+V  +++  +       + P+ILV  K+DL              
Sbjct: 272 DVFLICFSLISPASFENVKAKWYPEVSH--HCPNTPIILVGTKLDLREDKETIEKLKEKK 99

Query: 133 LRKVTRDQGKEMATKYNIP-YIETSA 157
           L  +T  QG  MA       Y+E SA
Sbjct: 98  LAPITYPQGLAMAKDIGAGKYLECSA 21
>32723
          Length = 384

 Score = 55.8 bits (133), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 32/103 (31%), Positives = 57/103 (55%), Gaps = 1/103 (0%)
 Frame = +2

Query: 71  QEEFSAMREQYMRTGDGFLIVYSVTDKASFEHVDRF-HQLILRVKDRESFPMILVANKVD 129
           QE F ++ + Y R+ +  ++VY V  + S+E + ++ H++ L    +      LV NK+D
Sbjct: 2   QERFRSITQSYYRSANALILVYDVCSQQSYESLPQWIHEIELYAGTK--VLAFLVGNKID 175

Query: 130 LMHLRKVTRDQGKEMATKYNIPYIETSAKDPPLNVDKTFHDLV 172
               R++    GKE A +Y + ++ETSAK+   NV+K F  + 
Sbjct: 176 QTDKREIPTHIGKEFAERYEMRFLETSAKEAD-NVEKLFSTIA 301
>19656
          Length = 428

 Score = 53.5 bits (127), Expect = 6e-08,   Method: Compositional matrix adjust.
 Identities = 27/78 (34%), Positives = 43/78 (55%)
 Frame = +3

Query: 26  KSALTIQFFQKIFVPDYDPTIEDSYLKHTEIDNQWAILDVLDTAGQEEFSAMREQYMRTG 85
           K+ L I +    F  +Y PT+ D+Y  +  +D +   L + DTAGQE++  +R       
Sbjct: 150 KTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGRPVNLGLWDTAGQEDYDRLRPLSYPQT 329

Query: 86  DGFLIVYSVTDKASFEHV 103
           D FL+ +SV   ASFE++
Sbjct: 330 DVFLLCFSVASPASFENI 383
>33374
          Length = 489

 Score = 51.2 bits (121), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 30/106 (28%), Positives = 59/106 (55%), Gaps = 3/106 (2%)
 Frame = +1

Query: 63  LDVLDTAGQEEFSAMREQYMRTGDGFLIVYSVTDKASFEHVDRFHQLILRVKDRESFPMI 122
            ++ DTAGQE + ++   Y R     ++VY +T++ +F     +    ++   R++ P I
Sbjct: 181 FEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNQDTFGRAKTW----VKELQRQASPNI 348

Query: 123 LVA---NKVDLMHLRKVTRDQGKEMATKYNIPYIETSAKDPPLNVD 165
           ++A   NK DL + R V  ++ +  A + ++ ++ETSAK   +NV+
Sbjct: 349 VIALAGNKADLANKRMVEFEEAQAYAEENSLLFMETSAK-TAMNVN 483
>19006
          Length = 568

 Score = 49.7 bits (117), Expect = 9e-07,   Method: Compositional matrix adjust.
 Identities = 34/114 (29%), Positives = 57/114 (50%)
 Frame = -2

Query: 26  KSALTIQFFQKIFVPDYDPTIEDSYLKHTEIDNQWAILDVLDTAGQEEFSAMREQYMRTG 85
           K+ L I F +  F   Y PT+ ++Y+   E+D++   L + DTAGQE++  +R       
Sbjct: 399 KTCLLIVFSKDQFPEVYVPTVFENYVADIEVDSKQVELALWDTAGQEDYDRLRPLSYPDT 220

Query: 86  DGFLIVYSVTDKASFEHVDRFHQLILRVKDRESFPMILVANKVDLMHLRKVTRD 139
           D  L+ +S+    S E++       +R     + P+ILV NK DL +     R+
Sbjct: 219 DVILMCFSIDSPDSLENIPEKWTPEVR-HFCPNVPIILVGNKKDLRNDENTKRE 61
>33380
          Length = 282

 Score = 47.4 bits (111), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 24/68 (35%), Positives = 38/68 (55%)
 Frame = +3

Query: 63  LDVLDTAGQEEFSAMREQYMRTGDGFLIVYSVTDKASFEHVDRFHQLILRVKDRESFPMI 122
           L + DTAGQE +  +   Y R   GF+++Y VT++ SF  V  +   I +    ++  ++
Sbjct: 66  LQIWDTAGQERYRTITTAYYRGAMGFILMYDVTNEESFNAVQDWCTQI-KTYSWDNAQVV 242

Query: 123 LVANKVDL 130
           LV NK DL
Sbjct: 243 LVGNKCDL 266
>26083
          Length = 432

 Score = 44.7 bits (104), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 34/128 (26%), Positives = 58/128 (45%), Gaps = 1/128 (0%)
 Frame = +1

Query: 1   MATSAVPSENLPTYKLXXXXXXXXXKSALTIQFFQKIFVPDYDPTIEDSYLKHTE-IDNQ 59
           M +S      L  +KL         K++L  +F    F   Y  TI   +L  T  ++++
Sbjct: 40  MTSSGEFGNPLRKFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDR 219

Query: 60  WAILDVLDTAGQEEFSAMREQYMRTGDGFLIVYSVTDKASFEHVDRFHQLILRVKDRESF 119
              L + DTAGQE F ++   Y+R     ++VY +T+  SF    ++   + R +     
Sbjct: 220 TIRLQLWDTAGQERFRSLIPSYIRDSSVAVVVYDITNANSFHQTSKWIDDV-RTERGSDV 396

Query: 120 PMILVANK 127
            ++LV NK
Sbjct: 397 IIMLVGNK 420
>31291
          Length = 446

 Score = 41.2 bits (95), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 37/125 (29%), Positives = 60/125 (48%), Gaps = 13/125 (10%)
 Frame = -1

Query: 63  LDVLDTAGQEEFSAMREQYMRTGDGFLIVYSVTDKASFEHVDRFHQLILRVKDRESFPMI 122
           L + DTAGQE++  +R       D F++ +S+  +AS ++V       +R  D    P++
Sbjct: 446 LQLWDTAGQEDYDRLRPLAYPNTDVFMLXFSLMSEASMKNVKVKWYPEIRHHD-PHVPIV 270

Query: 123 LVANKVDLMH----LRK--------VTRDQGKEMATKYNIP-YIETSAKDPPLNVDKTFH 169
           LV  K+DL      +RK        V+ +QG ++A       Y E S+K    N+   F 
Sbjct: 269 LVGTKLDLRQDKEAVRKLRSSRQDPVSSNQGNDLAKAIKAKRYFECSSKTQE-NLKTAFE 93

Query: 170 DLVRV 174
           + VRV
Sbjct: 92  ETVRV 78
>31928
          Length = 429

 Score = 39.3 bits (90), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 26/87 (29%), Positives = 41/87 (47%), Gaps = 4/87 (4%)
 Frame = +2

Query: 45  TIEDSYLKHTEID----NQWAILDVLDTAGQEEFSAMREQYMRTGDGFLIVYSVTDKASF 100
           TIED Y    E D     +  I D    A +     + + Y+   DGF++VY  T   SF
Sbjct: 53  TIEDIYTAVIETDRGVKEKVRIFDTGAAALETTEGDLPKHYLNFPDGFVLVYDTTSWESF 232

Query: 101 EHVDRFHQLILRVKDRESFPMILVANK 127
             +D+  + I + +D+    MI++ NK
Sbjct: 233 RRLDKLKKDIDKHRDKREVHMIVIGNK 313
>35581
          Length = 364

 Score = 32.7 bits (73), Expect = 0.095,   Method: Compositional matrix adjust.
 Identities = 18/51 (35%), Positives = 25/51 (49%), Gaps = 9/51 (17%)
 Frame = +2

Query: 61  AILDVLDTAGQEEFSAMREQYMRTGDGFLIVYSV---------TDKASFEH 102
           A +D+ DTAGQE + ++   Y R     LIVY           TD+A+  H
Sbjct: 194 ASVDLWDTAGQERYRSLTSSYYRDTKAVLIVYDAEHKLKLTDWTDRAAVPH 346
>00552
          Length = 455

 Score = 32.3 bits (72), Expect = 0.13,   Method: Compositional matrix adjust.
 Identities = 13/43 (30%), Positives = 25/43 (58%)
 Frame = -3

Query: 65  VLDTAGQEEFSAMREQYMRTGDGFLIVYSVTDKASFEHVDRFH 107
           + DTAGQE + ++R  + R  D  L+ +SV +  S + +  ++
Sbjct: 147 IWDTAGQERYKSLRTPFYRGTDCCLLTFSVDNLKSLQSLSDWY 19
>25655
          Length = 871

 Score = 28.1 bits (61), Expect = 2.3,   Method: Compositional matrix adjust.
 Identities = 12/17 (70%), Positives = 14/17 (82%)
 Frame = -3

Query: 142 KEMATKYNIPYIETSAK 158
           K MA  Y+IPY+ETSAK
Sbjct: 869 KHMAELYHIPYVETSAK 819
>10708
          Length = 2775

 Score = 28.1 bits (61), Expect = 2.8,   Method: Compositional matrix adjust.
 Identities = 13/41 (31%), Positives = 22/41 (53%)
 Frame = -2

Query: 63   LDVLDTAGQEEFSAMREQYMRTGDGFLIVYSVTDKASFEHV 103
            L + DTAGQE++  +R       D  L+ +S+    S E++
Sbjct: 2717 LALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENI 2595
>28114
          Length = 845

 Score = 26.6 bits (57), Expect = 7.4,   Method: Compositional matrix adjust.
 Identities = 28/101 (27%), Positives = 51/101 (50%), Gaps = 6/101 (5%)
 Frame = +1

Query: 49  SYLKHTEIDNQW-AILDVLDTAGQEEFSAMREQYMRTGDGFLIVYSVTDKASF--EHVDR 105
           S LK    D QW  ++DV + A  +E+   RE  ++  D  +  +  +DKA    + +++
Sbjct: 475 SLLKARLSDKQWDHVMDV-NAAMAQEYRIRREMLLKRLDVTIQSFMWSDKAKRXQDKINQ 651

Query: 106 FHQLI---LRVKDRESFPMILVANKVDLMHLRKVTRDQGKE 143
            +Q I   L V+ R   P IL A + DL  ++K +  + ++
Sbjct: 652 VYQPIRKELLVQTRIGIPEILAARE-DLTRIQKTSTGESRK 771
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|115496850|ref|NP_001070022.1| spectrin alpha 2 [Mus
musculus]
         (2478 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

28965                                                                 167   4e-41
01375                                                                 105   3e-22
34010                                                                  96   2e-19
38533                                                                  92   2e-18
22703                                                                  76   2e-13
26578                                                                  62   3e-09
17567                                                                  61   6e-09
14594                                                                  58   4e-08
29687                                                                  47   7e-05
11641                                                                  47   7e-05
29426                                                                  47   8e-05
16716                                                                  45   5e-04
20131                                                                  44   0.001
25483                                                                  44   0.001
17286                                                                  42   0.002
13664                                                                  42   0.002
14945                                                                  42   0.003
22063                                                                  42   0.004
21187                                                                  40   0.011
17613                                                                  40   0.012
19469                                                                  40   0.016
12324                                                                  39   0.038
30740                                                                  38   0.066
38338                                                                  37   0.081
28095                                                                  35   0.45 
01494                                                                  35   0.46 
20251                                                                  33   1.4  
17484                                                                  33   1.8  
06641                                                                  32   2.8  
03732                                                                  32   3.8  
11780                                                                  31   7.0  
11230                                                                  31   8.0  
>28965
          Length = 421

 Score =  167 bits (423), Expect = 4e-41,   Method: Compositional matrix adjust.
 Identities = 82/138 (59%), Positives = 107/138 (77%)
 Frame = +2

Query: 195 QTDLAAHEERVNEVSQFAAKLIQEQHPEEELIKTKQDEVNAAWQRLKGLALQRQGKLFGA 254
           Q DL  HE++V EV+  A +L+ + HPEEE I+ KQ+EVN AW+RL+ L+L RQ +L+GA
Sbjct: 2   QKDLQNHEDKVVEVNTLAEQLVTDGHPEEETIRQKQEEVNEAWKRLRQLSLLRQERLYGA 181

Query: 255 AEVQRFNRDVDETIGWIKEKEQLMASDDFGRDLASVQALLRKHEGLERDLAALEDKVKAL 314
            E+QRFNRD DETI WI+EK+ ++++DD+GRDLASVQ L RKHEG+ERDLAALE+KV AL
Sbjct: 182 HEIQRFNRDADETIAWIQEKDAVLSTDDYGRDLASVQTLQRKHEGVERDLAALEEKVNAL 361

Query: 315 CAEADRLQQSHPLSASQI 332
             E+ RLQ  H   + QI
Sbjct: 362 GTESVRLQGIHGDQSEQI 415

 Score =  116 bits (291), Expect = 1e-25,   Method: Compositional matrix adjust.
 Identities = 59/102 (57%), Positives = 77/102 (75%)
 Frame = +2

Query: 1189 KELNERWRSLQQLAEERSQLLGSAHEVQRFHRDADETKEWIEEKNQALNTDNYGHDLASV 1248
            +E+NE W+ L+QL+  R + L  AHE+QRF+RDADET  WI+EK+  L+TD+YG DLASV
Sbjct: 110  EEVNEAWKRLRQLSLLRQERLYGAHEIQRFNRDADETIAWIQEKDAVLSTDDYGRDLASV 289

Query: 1249 QALQRKHEGFERDLAALGDKVNSLGETAQRLIQSHPESAEDL 1290
            Q LQRKHEG ERDLAAL +KVN+LG  + RL   H + +E +
Sbjct: 290  QTLQRKHEGVERDLAALEEKVNALGTESVRLQGIHGDQSEQI 415

 Score = 84.3 bits (207), Expect = 5e-16,   Method: Compositional matrix adjust.
 Identities = 38/118 (32%), Positives = 79/118 (66%)
 Frame = +2

Query: 1691 DISAHEDRLKDLNSQADSLMTSSAFDTSQVKEKRDTINGRFQKIKSMATSRRAKLSESHR 1750
            D+  HED++ ++N+ A+ L+T    +   +++K++ +N  +++++ ++  R+ +L  +H 
Sbjct: 8    DLQNHEDKVVEVNTLAEQLVTDGHPEEETIRQKQEEVNEAWKRLRQLSLLRQERLYGAHE 187

Query: 1751 LHQFFRDMDDEESWIKEKKLLVSSEDYGRDLTGVQNLRKKHKRLEAELAAHEPAIQGV 1808
            + +F RD D+  +WI+EK  ++S++DYGRDL  VQ L++KH+ +E +LAA E  +  +
Sbjct: 188  IQRFNRDADETIAWIQEKDAVLSTDDYGRDLASVQTLQRKHEGVERDLAALEEKVNAL 361

 Score = 71.2 bits (173), Expect = 5e-12,   Method: Compositional matrix adjust.
 Identities = 42/120 (35%), Positives = 69/120 (57%)
 Frame = +2

Query: 1797 ELAAHEPAIQGVLDTGKKLSDDNTIGQEEIQQRLAQFVEHWKELKQLAAARGQRLEESLE 1856
            +L  HE  +  V    ++L  D    +E I+Q+  +  E WK L+QL+  R +RL  + E
Sbjct: 8    DLQNHEDKVVEVNTLAEQLVTDGHPEEETIRQKQEEVNEAWKRLRQLSLLRQERLYGAHE 187

Query: 1857 YQQFVANVEEEEAWINEKMTLVASEDYGDTLAAIQGLLKKHEAFETDFTVHKDRVNDVCT 1916
             Q+F  + +E  AWI EK  +++++DYG  LA++Q L +KHE  E D    +++VN + T
Sbjct: 188  IQRFNRDADETIAWIQEKDAVLSTDDYGRDLASVQTLQRKHEGVERDLAALEEKVNALGT 367

 Score = 70.5 bits (171), Expect = 8e-12,   Method: Compositional matrix adjust.
 Identities = 36/120 (30%), Positives = 69/120 (57%)
 Frame = +2

Query: 830 QAEIAGHEPRIKAVTQKGNAMVEEGHFAAEDVKAKLSELNQKWEALKAKASQRRQDLEDS 889
           Q ++  HE ++  V      +V +GH   E ++ K  E+N+ W+ L+  +  R++ L  +
Sbjct: 2   QKDLQNHEDKVVEVNTLAEQLVTDGHPEEETIRQKQEEVNEAWKRLRQLSLLRQERLYGA 181

Query: 890 LQAQQYFADANEAESWMREKEPIVGSTDYGKDEDSAEALLKKHEALMSDLSAYGSSIQAL 949
            + Q++  DA+E  +W++EK+ ++ + DYG+D  S + L +KHE +  DL+A    + AL
Sbjct: 182 HEIQRFNRDADETIAWIQEKDAVLSTDDYGRDLASVQTLQRKHEGVERDLAALEEKVNAL 361

 Score = 69.7 bits (169), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 36/126 (28%), Positives = 77/126 (61%)
 Frame = +2

Query: 620 ELSANQSRIDALEKAGQKLIDVNHYAKEEVAARMNEVISLWKKLLEATELKGIKLREANQ 679
           +L  ++ ++  +    ++L+   H  +E +  +  EV   WK+L + + L+  +L  A++
Sbjct: 8   DLQNHEDKVVEVNTLAEQLVTDGHPEEETIRQKQEEVNEAWKRLRQLSLLRQERLYGAHE 187

Query: 680 QQQFNRNVEDIELWLYEVEGHLASDDYGKDLTNVQNLQKKHALLEADVAAHQDRIDGITI 739
            Q+FNR+ ++   W+ E +  L++DDYG+DL +VQ LQ+KH  +E D+AA +++++ +  
Sbjct: 188 IQRFNRDADETIAWIQEKDAVLSTDDYGRDLASVQTLQRKHEGVERDLAALEEKVNALGT 367

Query: 740 QARQFQ 745
           ++ + Q
Sbjct: 368 ESVRLQ 385

 Score = 66.6 bits (161), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 37/127 (29%), Positives = 80/127 (62%), Gaps = 2/127 (1%)
 Frame = +2

Query: 91  EVQANSGAIVKLDETGNLMISEGHFASETIRTRLMELHRQWELL--LEKMREKGIKLLQA 148
           ++Q +   +V+++     ++++GH   ETIR +  E++  W+ L  L  +R++  +L  A
Sbjct: 8   DLQNHEDKVVEVNTLAEQLVTDGHPEEETIRQKQEEVNEAWKRLRQLSLLRQE--RLYGA 181

Query: 149 QKLVQYLRECEDVMDWINDKEAIVTSEELGQDLEHVEVLQKKFEEFQTDLAAHEERVNEV 208
            ++ ++ R+ ++ + WI +K+A++++++ G+DL  V+ LQ+K E  + DLAA EE+VN +
Sbjct: 182 HEIQRFNRDADETIAWIQEKDAVLSTDDYGRDLASVQTLQRKHEGVERDLAALEEKVNAL 361

Query: 209 SQFAAKL 215
              + +L
Sbjct: 362 GTESVRL 382

 Score = 66.2 bits (160), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 33/118 (27%), Positives = 71/118 (60%)
 Frame = +2

Query: 726 DVAAHQDRIDGITIQARQFQDAGHFDAENIKKKQEALVARYEALKEPMVARKQKLADSLR 785
           D+  H+D++  +   A Q    GH + E I++KQE +   ++ L++  + R+++L  +  
Sbjct: 8   DLQNHEDKVVEVNTLAEQLVTDGHPEEETIRQKQEEVNEAWKRLRQLSLLRQERLYGAHE 187

Query: 786 LQQLFRDVEDEETWIREKEPIAASTNRGKDLIGVQNLLKKHQALQAEIAGHEPRIKAV 843
           +Q+  RD ++   WI+EK+ + ++ + G+DL  VQ L +KH+ ++ ++A  E ++ A+
Sbjct: 188 IQRFNRDADETIAWIQEKDAVLSTDDYGRDLASVQTLQRKHEGVERDLAALEEKVNAL 361

 Score = 65.1 bits (157), Expect = 4e-10,   Method: Compositional matrix adjust.
 Identities = 41/113 (36%), Positives = 60/113 (53%)
 Frame = +2

Query: 1903 DFTVHKDRVNDVCTNGQDLIKKNNHHEENISSKMKGLNGKVSDLEKAAAQRKAKLDENSA 1962
            D   H+D+V +V T  + L+   +  EE I  K + +N     L + +  R+ +L     
Sbjct: 8    DLQNHEDKVVEVNTLAEQLVTDGHPEEETIRQKQEEVNEAWKRLRQLSLLRQERLYGAHE 187

Query: 1963 FLQFNWKADVVESWIGEKENSLKTDDYGRDLSSVQTLLTKQETFDAGLQAFQQ 2015
              +FN  AD   +WI EK+  L TDDYGRDL+SVQTL  K E  +  L A ++
Sbjct: 188  IQRFNRDADETIAWIQEKDAVLSTDDYGRDLASVQTLQRKHEGVERDLAALEE 346

 Score = 60.5 bits (145), Expect = 8e-09,   Method: Compositional matrix adjust.
 Identities = 37/121 (30%), Positives = 65/121 (53%)
 Frame = +2

Query: 413 HEDSFKSADESGQALLAASHYASDEVREKLSILSEERTALLELWELRRQQYEQCMDLQLF 472
           HED     +   + L+   H   + +R+K   ++E    L +L  LR+++     ++Q F
Sbjct: 20  HEDKVVEVNTLAEQLVTDGHPEEETIRQKQEEVNEAWKRLRQLSLLRQERLYGAHEIQRF 199

Query: 473 YRDTEQVDNWMSKQEAFLLNEDLGDSLDSVEALLKKHEDFEKSLSAQEEKITALDEFATK 532
            RD ++   W+ +++A L  +D G  L SV+ L +KHE  E+ L+A EEK+ AL   + +
Sbjct: 200 NRDADETIAWIQEKDAVLSTDDYGRDLASVQTLQRKHEGVERDLAALEEKVNALGTESVR 379

Query: 533 L 533
           L
Sbjct: 380 L 382

 Score = 60.5 bits (145), Expect = 9e-09,   Method: Compositional matrix adjust.
 Identities = 36/124 (29%), Positives = 71/124 (57%), Gaps = 2/124 (1%)
 Frame = +2

Query: 1599 NSLIERGACAG--SEDAVKARLAALADQWQFLVQKSAEKSQKLKEANKQQNFNTGIKDFD 1656
            N+L E+    G   E+ ++ +   + + W+ L Q S  + ++L  A++ Q FN    +  
Sbjct: 44   NTLAEQLVTDGHPEEETIRQKQEEVNEAWKRLRQLSLLRQERLYGAHEIQRFNRDADETI 223

Query: 1657 FWLSEVEALLASEDYGKDLASVNNLLKKHQLLEADISAHEDRLKDLNSQADSLMTSSAFD 1716
             W+ E +A+L+++DYG+DLASV  L +KH+ +E D++A E+++  L +++  L       
Sbjct: 224  AWIQEKDAVLSTDDYGRDLASVQTLQRKHEGVERDLAALEEKVNALGTESVRLQGIHGDQ 403

Query: 1717 TSQV 1720
            + Q+
Sbjct: 404  SEQI 415

 Score = 53.9 bits (128), Expect = 7e-07,   Method: Compositional matrix adjust.
 Identities = 31/105 (29%), Positives = 61/105 (58%), Gaps = 1/105 (0%)
 Frame = +2

Query: 1259 ERDLAALGDKVNSLGETAQRLIQ-SHPESAEDLKEKCTELNQAWTSLGKRADQRKAKLGD 1317
            ++DL    DKV  +   A++L+   HPE  E +++K  E+N+AW  L + +  R+ +L  
Sbjct: 2    QKDLQNHEDKVVEVNTLAEQLVTDGHPEE-ETIRQKQEEVNEAWKRLRQLSLLRQERLYG 178

Query: 1318 SHDLQRFLSDFRDLMSWINGIRGLVSSDELAKDVTGAEALLERHQ 1362
            +H++QRF  D  + ++WI     ++S+D+  +D+   + L  +H+
Sbjct: 179  AHEIQRFNRDADETIAWIQEKDAVLSTDDYGRDLASVQTLQRKHE 313

 Score = 52.8 bits (125), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 32/104 (30%), Positives = 58/104 (55%)
 Frame = +2

Query: 1381 FGQQLLAHGHYASPEIKEKLDILDQERTDLEKAWVQRRMMLDHCLELQLFHRDCEQAENW 1440
              +QL+  GH     I++K + +++    L +  + R+  L    E+Q F+RD ++   W
Sbjct: 50   LAEQLVTDGHPEEETIRQKQEEVNEAWKRLRQLSLLRQERLYGAHEIQRFNRDADETIAW 229

Query: 1441 MAAREAFLNTEDKGDSLDSVEALIKKHEDFDKAINVQEEKIAAL 1484
            +  ++A L+T+D G  L SV+ L +KHE  ++ +   EEK+ AL
Sbjct: 230  IQEKDAVLSTDDYGRDLASVQTLQRKHEGVERDLAALEEKVNAL 361

 Score = 52.4 bits (124), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 34/124 (27%), Positives = 66/124 (53%), Gaps = 1/124 (0%)
 Frame = +2

Query: 1472 KAINVQEEKIAALQAFADQLIAVDHYAKGDIANRRNEVLDRWRRLKAQMIEKRSKLGESQ 1531
            K +   E+K+  +   A+QL+   H  +  I  ++ EV + W+RL+   + ++ +L  + 
Sbjct: 5    KDLQNHEDKVVEVNTLAEQLVTDGHPEEETIRQKQEEVNEAWKRLRQLSLLRQERLYGAH 184

Query: 1532 TLQQFSRDVDEIEAWISEKLQTASDESY-KDPTNIQLSKLLSKHQKHQAFEAELHANADR 1590
             +Q+F+RD DE  AWI EK    S + Y +D  ++Q     +  +KH+  E +L A  ++
Sbjct: 185  EIQRFNRDADETIAWIQEKDAVLSTDDYGRDLASVQ-----TLQRKHEGVERDLAALEEK 349

Query: 1591 IRGV 1594
            +  +
Sbjct: 350  VNAL 361

 Score = 52.4 bits (124), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 31/120 (25%), Positives = 69/120 (57%), Gaps = 1/120 (0%)
 Frame = +2

Query: 513 EKSLSAQEEKITALDEFATKLIQNNHYAMEDVATRRDALLSRRNALHERAMHRRAQLADS 572
           +K L   E+K+  ++  A +L+ + H   E +  +++ +      L + ++ R+ +L  +
Sbjct: 2   QKDLQNHEDKVVEVNTLAEQLVTDGHPEEETIRQKQEEVNEAWKRLRQLSLLRQERLYGA 181

Query: 573 FHLQQFFRDSDELKSWVNEKMKT-ATDEAYKDPSNLQGKVQKHQAFEAELSANQSRIDAL 631
             +Q+F RD+DE  +W+ EK    +TD+  +D +++Q   +KH+  E +L+A + +++AL
Sbjct: 182 HEIQRFNRDADETIAWIQEKDAVLSTDDYGRDLASVQTLQRKHEGVERDLAALEEKVNAL 361

 Score = 50.8 bits (120), Expect = 6e-06,   Method: Compositional matrix adjust.
 Identities = 29/83 (34%), Positives = 54/83 (65%), Gaps = 1/83 (1%)
 Frame = +2

Query: 13  EDIQERRQQVLDRYHRFKELSTLRRQKLEDSYRFQFFQRDAEELEKWIQEKLQVASDENY 72
           E I++++++V + + R ++LS LR+++L  ++  Q F RDA+E   WIQEK  V S ++Y
Sbjct: 89  ETIRQKQEEVNEAWKRLRQLSLLRQERLYGAHEIQRFNRDADETIAWIQEKDAVLSTDDY 268

Query: 73  -KDPTNLQGKLQKHQAFEAEVQA 94
            +D  ++Q   +KH+  E ++ A
Sbjct: 269 GRDLASVQTLQRKHEGVERDLAA 337

 Score = 50.4 bits (119), Expect = 9e-06,   Method: Compositional matrix adjust.
 Identities = 32/105 (30%), Positives = 59/105 (56%), Gaps = 1/105 (0%)
 Frame = +2

Query: 301 ERDLAALEDKVKALCAEADRL-QQSHPLSASQIQVKREELITNWEQIRTLAAERHARLDD 359
           ++DL   EDKV  +   A++L    HP   + I+ K+EE+   W+++R L+  R  RL  
Sbjct: 2   QKDLQNHEDKVVEVNTLAEQLVTDGHPEEET-IRQKQEEVNEAWKRLRQLSLLRQERLYG 178

Query: 360 SYRLQRFLADFRDLTSWVTEMKALINADELANDVAGAEALLDRHQ 404
           ++ +QRF  D  +  +W+ E  A+++ D+   D+A  + L  +H+
Sbjct: 179 AHEIQRFNRDADETIAWIQEKDAVLSTDDYGRDLASVQTLQRKHE 313
>01375
          Length = 2323

 Score =  105 bits (261), Expect = 3e-22,   Method: Composition-based stats.
 Identities = 48/73 (65%), Positives = 60/73 (82%)
 Frame = +1

Query: 2406 TENVKSSEEIESAFRALSSEGKPYVTKEELYQNLTREQADYCVSHMKPYVDGKGRELPTA 2465
            TENV+SS E+E AFRAL+S  KP++T +ELY NLT+EQADYC+  M+PYVD  GR +P A
Sbjct: 4    TENVQSSSEVEQAFRALTSGEKPFITAQELYANLTKEQADYCIGRMQPYVDKTGRTIPDA 183

Query: 2466 FDYVEFTRSLFVN 2478
            +DYV+FTR LFVN
Sbjct: 184  YDYVDFTRQLFVN 222
>34010
          Length = 832

 Score = 95.9 bits (237), Expect = 2e-19,   Method: Compositional matrix adjust.
 Identities = 54/135 (40%), Positives = 78/135 (57%)
 Frame = +3

Query: 392 DVAGAEALLDRHQEHKGEIDAHEDSFKSADESGQALLAASHYASDEVREKLSILSEERTA 451
           DV+G E L++ HQ  K EIDA E++F      G+ LL   HY  +EVREKL  L+ ER  
Sbjct: 93  DVSGVELLMNNHQSLKAEIDAREENFAICINLGRDLLNRKHYRQEEVREKLIQLTLERLD 272

Query: 452 LLELWELRRQQYEQCMDLQLFYRDTEQVDNWMSKQEAFLLNEDLGDSLDSVEALLKKHED 511
           + +LW+ R +  +  +++  F RD    + W+  QE + LN+DLGD+LD+VE L+K  + 
Sbjct: 273 MTDLWKDRWEHLQLILEVYQFARDAAVAEAWLVAQEQYFLNQDLGDTLDAVENLIKSMKP 452

Query: 512 FEKSLSAQEEKITAL 526
             KS      KI  L
Sbjct: 453 L-KSCCHARRKICCL 494

 Score = 86.3 bits (212), Expect = 2e-16,   Method: Compositional matrix adjust.
 Identities = 52/138 (37%), Positives = 71/138 (51%)
 Frame = +3

Query: 1348 AKDVTGAEALLERHQEHRTEIDARAGTFQAFEQFGQQLLAHGHYASPEIKEKLDILDQER 1407
             +DV+G E L+  HQ  + EIDAR   F      G+ LL   HY   E++EKL  L  ER
Sbjct: 87   PRDVSGVELLMNNHQSLKAEIDAREENFAICINLGRDLLNRKHYRQEEVREKLIQLTLER 266

Query: 1408 TDLEKAWVQRRMMLDHCLELQLFHRDCEQAENWMAAREAFLNTEDKGDSLDSVEALIKKH 1467
             D+   W  R   L   LE+  F RD   AE W+ A+E +   +D GD+LD+VE LIK  
Sbjct: 267  LDMTDLWKDRWEHLQLILEVYQFARDAAVAEAWLVAQEQYFLNQDLGDTLDAVENLIKSM 446

Query: 1468 EDFDKAINVQEEKIAALQ 1485
            +      + +  KI  L+
Sbjct: 447  KPLKSCCHAR-RKICCLR 497

 Score = 60.1 bits (144), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 42/149 (28%), Positives = 74/149 (49%)
 Frame = +3

Query: 1779 RDLTGVQNLRKKHKRLEAELAAHEPAIQGVLDTGKKLSDDNTIGQEEIQQRLAQFVEHWK 1838
            RD++GV+ L   H+ L+AE+ A E      ++ G+ L +     QEE++++L Q      
Sbjct: 90   RDVSGVELLMNNHQSLKAEIDAREENFAICINLGRDLLNRKHYRQEEVREKLIQLTLERL 269

Query: 1839 ELKQLAAARGQRLEESLEYQQFVANVEEEEAWINEKMTLVASEDYGDTLAAIQGLLKKHE 1898
            ++  L   R + L+  LE  QF  +    EAW+  +     ++D GDTL A++ L+K  +
Sbjct: 270  DMTDLWKDRWEHLQLILEVYQFARDAAVAEAWLVAQEQYFLNQDLGDTLDAVENLIKSMK 449

Query: 1899 AFETDFTVHKDRVNDVCTNGQDLIKKNNH 1927
              ++    H  R   +C      ++K NH
Sbjct: 450  PLKS--CCHARR--KICC-----LRKTNH 509

 Score = 53.5 bits (127), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 37/132 (28%), Positives = 63/132 (47%)
 Frame = +3

Query: 810 TNRGKDLIGVQNLLKKHQALQAEIAGHEPRIKAVTQKGNAMVEEGHFAAEDVKAKLSELN 869
             + +D+ GV+ L+  HQ+L+AEI   E         G  ++   H+  E+V+ KL +L 
Sbjct: 78  AGKPRDVSGVELLMNNHQSLKAEIDAREENFAICINLGRDLLNRKHYRQEEVREKLIQLT 257

Query: 870 QKWEALKAKASQRRQDLEDSLQAQQYFADANEAESWMREKEPIVGSTDYGKDEDSAEALL 929
            +   +      R + L+  L+  Q+  DA  AE+W+  +E    + D G   D+ E L+
Sbjct: 258 LERLDMTDLWKDRWEHLQLILEVYQFARDAAVAEAWLVAQEQYFLNQDLGDTLDAVENLI 437

Query: 930 KKHEALMSDLSA 941
           K  + L S   A
Sbjct: 438 KSMKPLKSCCHA 473

 Score = 41.2 bits (95), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 37/128 (28%), Positives = 60/128 (46%), Gaps = 6/128 (4%)
 Frame = +3

Query: 597 TDEAYKDPSNLQGK---VQKHQAFEAELSANQSRIDALEKAGQKLIDVNHYAKEEVAARM 653
           TDE    P ++ G    +  HQ+ +AE+ A +         G+ L++  HY +EEV  ++
Sbjct: 66  TDEHAGKPRDVSGVELLMNNHQSLKAEIDAREENFAICINLGRDLLNRKHYRQEEVREKL 245

Query: 654 NEVISLWKKLLEATEL---KGIKLREANQQQQFNRNVEDIELWLYEVEGHLASDDYGKDL 710
              I L  + L+ T+L   +   L+   +  QF R+    E WL   E +  + D G  L
Sbjct: 246 ---IQLTLERLDMTDLWKDRWEHLQLILEVYQFARDAAVAEAWLVAQEQYFLNQDLGDTL 416

Query: 711 TNVQNLQK 718
             V+NL K
Sbjct: 417 DAVENLIK 440

 Score = 40.0 bits (92), Expect = 0.012,   Method: Compositional matrix adjust.
 Identities = 31/124 (25%), Positives = 57/124 (45%)
 Frame = +3

Query: 1673 KDLASVNNLLKKHQLLEADISAHEDRLKDLNSQADSLMTSSAFDTSQVKEKRDTINGRFQ 1732
            +D++ V  L+  HQ L+A+I A E+      +    L+    +   +V+EK   +     
Sbjct: 90   RDVSGVELLMNNHQSLKAEIDAREENFAICINLGRDLLNRKHYRQEEVREKLIQLTLERL 269

Query: 1733 KIKSMATSRRAKLSESHRLHQFFRDMDDEESWIKEKKLLVSSEDYGRDLTGVQNLRKKHK 1792
             +  +   R   L     ++QF RD    E+W+  ++    ++D G  L  V+NL K  K
Sbjct: 270  DMTDLWKDRWEHLQLILEVYQFARDAAVAEAWLVAQEQYFLNQDLGDTLDAVENLIKSMK 449

Query: 1793 RLEA 1796
             L++
Sbjct: 450  PLKS 461
>38533
          Length = 380

 Score = 92.4 bits (228), Expect = 2e-18,   Method: Compositional matrix adjust.
 Identities = 47/120 (39%), Positives = 68/120 (56%), Gaps = 1/120 (0%)
 Frame = +1

Query: 793 VEDEETWIR-EKEPIAASTNRGKDLIGVQNLLKKHQALQAEIAGHEPRIKAVTQKGNAMV 851
           VEDE +W   +++PIA ST+ G  L  VQNL+KKHQAL++EI  HEP I AV      M+
Sbjct: 1   VEDELSWYY*DRKPIAESTDLGNSLTAVQNLMKKHQALESEIVAHEPLIDAVATSAQQMI 180

Query: 852 EEGHFAAEDVKAKLSELNQKWEALKAKASQRRQDLEDSLQAQQYFADANEAESWMREKEP 911
              HFA  D++ +L +L    +  +      + +      AQ+++ + NE E WM EK P
Sbjct: 181 RTKHFATADIQTRLDDLTSPAQRSQVFYLL*KVETAGCFGAQKFYMEVNEVELWMNEKIP 360

 Score = 64.3 bits (155), Expect = 5e-10,   Method: Compositional matrix adjust.
 Identities = 34/101 (33%), Positives = 57/101 (56%)
 Frame = +1

Query: 494 DLGDSLDSVEALLKKHEDFEKSLSAQEEKITALDEFATKLIQNNHYAMEDVATRRDALLS 553
           DLG+SL +V+ L+KKH+  E  + A E  I A+   A ++I+  H+A  D+ TR D L S
Sbjct: 58  DLGNSLTAVQNLMKKHQALESEIVAHEPLIDAVATSAQQMIRTKHFATADIQTRLDDLTS 237

Query: 554 RRNALHERAMHRRAQLADSFHLQQFFRDSDELKSWVNEKMK 594
                    +  + + A  F  Q+F+ + +E++ W+NEK+ 
Sbjct: 238 PAQRSQVFYLL*KVETAGCFGAQKFYMEVNEVELWMNEKIP 360

 Score = 63.2 bits (152), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 39/119 (32%), Positives = 57/119 (47%), Gaps = 1/119 (0%)
 Frame = +1

Query: 1758 MDDEESWIK-EKKLLVSSEDYGRDLTGVQNLRKKHKRLEAELAAHEPAIQGVLDTGKKLS 1816
            ++DE SW   ++K +  S D G  LT VQNL KKH+ LE+E+ AHEP I  V  + +++ 
Sbjct: 1    VEDELSWYY*DRKPIAESTDLGNSLTAVQNLMKKHQALESEIVAHEPLIDAVATSAQQMI 180

Query: 1817 DDNTIGQEEIQQRLAQFVEHWKELKQLAAARGQRLEESLEYQQFVANVEEEEAWINEKM 1875
                    +IQ RL       +  +                Q+F   V E E W+NEK+
Sbjct: 181  RTKHFATADIQTRLDDLTSPAQRSQVFYLL*KVETAGCFGAQKFYMEVNEVELWMNEKI 357

 Score = 60.8 bits (146), Expect = 7e-09,   Method: Compositional matrix adjust.
 Identities = 39/120 (32%), Positives = 60/120 (50%), Gaps = 1/120 (0%)
 Frame = +1

Query: 687 VEDIELWLYEVEGHLA-SDDYGKDLTNVQNLQKKHALLEADVAAHQDRIDGITIQARQFQ 745
           VED   W Y     +A S D G  LT VQNL KKH  LE+++ AH+  ID +   A+Q  
Sbjct: 1   VEDELSWYY*DRKPIAESTDLGNSLTAVQNLMKKHQALESEIVAHEPLIDAVATSAQQMI 180

Query: 746 DAGHFDAENIKKKQEALVARYEALKEPMVARKQKLADSLRLQQLFRDVEDEETWIREKEP 805
              HF   +I+ + + L +  +  +   +  K + A     Q+ + +V + E W+ EK P
Sbjct: 181 RTKHFATADIQTRLDDLTSPAQRSQVFYLL*KVETAGCFGAQKFYMEVNEVELWMNEKIP 360

 Score = 55.8 bits (133), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 31/108 (28%), Positives = 57/108 (52%)
 Frame = +1

Query: 1444 REAFLNTEDKGDSLDSVEALIKKHEDFDKAINVQEEKIAALQAFADQLIAVDHYAKGDIA 1503
            R+    + D G+SL +V+ L+KKH+  +  I   E  I A+   A Q+I   H+A  DI 
Sbjct: 34   RKPIAESTDLGNSLTAVQNLMKKHQALESEIVAHEPLIDAVATSAQQMIRTKHFATADIQ 213

Query: 1504 NRRNEVLDRWRRLKAQMIEKRSKLGESQTLQQFSRDVDEIEAWISEKL 1551
             R +++    +R +   +  + +       Q+F  +V+E+E W++EK+
Sbjct: 214  TRLDDLTSPAQRSQVFYLL*KVETAGCFGAQKFYMEVNEVELWMNEKI 357

 Score = 53.9 bits (128), Expect = 7e-07,   Method: Compositional matrix adjust.
 Identities = 27/101 (26%), Positives = 54/101 (53%)
 Frame = +1

Query: 1668 SEDYGKDLASVNNLLKKHQLLEADISAHEDRLKDLNSQADSLMTSSAFDTSQVKEKRDTI 1727
            S D G  L +V NL+KKHQ LE++I AHE  +  + + A  ++ +  F T+ ++ + D +
Sbjct: 52   STDLGNSLTAVQNLMKKHQALESEIVAHEPLIDAVATSAQQMIRTKHFATADIQTRLDDL 231

Query: 1728 NGRFQKIKSMATSRRAKLSESHRLHQFFRDMDDEESWIKEK 1768
                Q+ +      + + +      +F+ ++++ E W+ EK
Sbjct: 232  TSPAQRSQVFYLL*KVETAGCFGAQKFYMEVNEVELWMNEK 354

 Score = 47.8 bits (112), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 25/106 (23%), Positives = 52/106 (49%)
 Frame = +1

Query: 381 KALINADELANDVAGAEALLDRHQEHKGEIDAHEDSFKSADESGQALLAASHYASDEVRE 440
           K +  + +L N +   + L+ +HQ  + EI AHE    +   S Q ++   H+A+ +++ 
Sbjct: 37  KPIAESTDLGNSLTAVQNLMKKHQALESEIVAHEPLIDAVATSAQQMIRTKHFATADIQT 216

Query: 441 KLSILSEERTALLELWELRRQQYEQCMDLQLFYRDTEQVDNWMSKQ 486
           +L  L+         + L + +   C   Q FY +  +V+ WM+++
Sbjct: 217 RLDDLTSPAQRSQVFYLL*KVETAGCFGAQKFYMEVNEVELWMNEK 354

 Score = 47.8 bits (112), Expect = 6e-05,   Method: Compositional matrix adjust.
 Identities = 25/92 (27%), Positives = 52/92 (56%)
 Frame = +1

Query: 605 SNLQGKVQKHQAFEAELSANQSRIDALEKAGQKLIDVNHYAKEEVAARMNEVISLWKKLL 664
           + +Q  ++KHQA E+E+ A++  IDA+  + Q++I   H+A  ++  R++++ S  ++  
Sbjct: 76  TAVQNLMKKHQALESEIVAHEPLIDAVATSAQQMIRTKHFATADIQTRLDDLTSPAQRSQ 255

Query: 665 EATELKGIKLREANQQQQFNRNVEDIELWLYE 696
               L  ++       Q+F   V ++ELW+ E
Sbjct: 256 VFYLL*KVETAGCFGAQKFYMEVNEVELWMNE 351

 Score = 42.0 bits (97), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 24/103 (23%), Positives = 48/103 (46%)
 Frame = +1

Query: 1339 RGLVSSDELAKDVTGAEALLERHQEHRTEIDARAGTFQAFEQFGQQLLAHGHYASPEIKE 1398
            + +  S +L   +T  + L+++HQ   +EI A      A     QQ++   H+A+ +I+ 
Sbjct: 37   KPIAESTDLGNSLTAVQNLMKKHQALESEIVAHEPLIDAVATSAQQMIRTKHFATADIQT 216

Query: 1399 KLDILDQERTDLEKAWVQRRMMLDHCLELQLFHRDCEQAENWM 1441
            +LD L       +  ++  ++    C   Q F+ +  + E WM
Sbjct: 217  RLDDLTSPAQRSQVFYLL*KVETAGCFGAQKFYMEVNEVELWM 345

 Score = 41.2 bits (95), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 33/98 (33%), Positives = 49/98 (50%), Gaps = 5/98 (5%)
 Frame = +1

Query: 76  TNLQGKLQKHQAFEAEVQANSGAIVKLDETGNLMISEGHFASETIRTRLMEL-----HRQ 130
           T +Q  ++KHQA E+E+ A+   I  +  +   MI   HFA+  I+TRL +L       Q
Sbjct: 76  TAVQNLMKKHQALESEIVAHEPLIDAVATSAQQMIRTKHFATADIQTRLDDLTSPAQRSQ 255

Query: 131 WELLLEKMREKGIKLLQAQKLVQYLRECEDVMDWINDK 168
              LL K+   G     AQK   +  E  +V  W+N+K
Sbjct: 256 VFYLL*KVETAG--CFGAQK---FYMEVNEVELWMNEK 354

 Score = 36.6 bits (83), Expect = 0.12,   Method: Compositional matrix adjust.
 Identities = 20/52 (38%), Positives = 31/52 (59%), Gaps = 1/52 (1%)
 Frame = +1

Query: 904 SWMR-EKEPIVGSTDYGKDEDSAEALLKKHEALMSDLSAYGSSIQALREQAQ 954
           SW   +++PI  STD G    + + L+KKH+AL S++ A+   I A+   AQ
Sbjct: 16  SWYY*DRKPIAESTDLGNSLTAVQNLMKKHQALESEIVAHEPLIDAVATSAQ 171
>22703
          Length = 906

 Score = 75.9 bits (185), Expect = 2e-13,   Method: Compositional matrix adjust.
 Identities = 49/149 (32%), Positives = 76/149 (51%), Gaps = 7/149 (4%)
 Frame = -3

Query: 1374 TFQAFEQFGQQLLAHGHYASPEIKEKLDILDQERTDLEKAWVQRRMMLDHCLELQLFHRD 1433
             F  F + G+  +A+GH+ S EI+EK+  LDQ    L +    RR +    LE Q    +
Sbjct: 883  PFDKFRKTGRSFIANGHFLSKEIEEKIKQLDQSLEGLIRNLEHRRKLHQQNLEAQQLRHE 704

Query: 1434 CEQAENWMAAREAFLNTEDKGDSLDSVEALIKKHEDFDKAINVQEEKIAALQ-------A 1486
             EQ E WM  RE  L  +  G+S++  E ++++H+ F K +  QE+++ ALQ       A
Sbjct: 703  MEQIEAWMNLREPLLKEKKFGESIEGAEEMLRRHD*F*KTVTAQEDRVNALQRNEKVKNA 524

Query: 1487 FADQLIAVDHYAKGDIANRRNEVLDRWRR 1515
            FA+Q +        D A R  + LD  R+
Sbjct: 523  FAEQKLKEQQQQVEDEARRERDRLDELRK 437

 Score = 71.2 bits (173), Expect = 5e-12,   Method: Compositional matrix adjust.
 Identities = 42/145 (28%), Positives = 82/145 (56%), Gaps = 8/145 (5%)
 Frame = -3

Query: 415 DSFKSADESGQALLAASHYASDEVREKLSILSEERTALLELWELRRQQYEQCMDLQLFYR 474
           + F    ++G++ +A  H+ S E+ EK+  L +    L+   E RR+ ++Q ++ Q    
Sbjct: 886 EPFDKFRKTGRSFIANGHFLSKEIEEKIKQLDQSLEGLIRNLEHRRKLHQQNLEAQQLRH 707

Query: 475 DTEQVDNWMSKQEAFLLNEDLGDSLDSVEALLKKHEDFEKSLSAQEEKITAL-------D 527
           + EQ++ WM+ +E  L  +  G+S++  E +L++H+ F K+++AQE+++ AL       +
Sbjct: 706 EMEQIEAWMNLREPLLKEKKFGESIEGAEEMLRRHD*F*KTVTAQEDRVNALQRNEKVKN 527

Query: 528 EFATKLIQNNHYAMEDVATR-RDAL 551
            FA + ++     +ED A R RD L
Sbjct: 526 AFAEQKLKEQQQQVEDEARRERDRL 452

 Score = 57.4 bits (137), Expect = 6e-08,   Method: Compositional matrix adjust.
 Identities = 32/117 (27%), Positives = 63/117 (53%)
 Frame = -3

Query: 833 IAGHEPRIKAVTQKGNAMVEEGHFAAEDVKAKLSELNQKWEALKAKASQRRQDLEDSLQA 892
           I G EP      + G + +  GHF +++++ K+ +L+Q  E L      RR+  + +L+A
Sbjct: 898 IYGREP-FDKFRKTGRSFIANGHFLSKEIEEKIKQLDQSLEGLIRNLEHRRKLHQQNLEA 722

Query: 893 QQYFADANEAESWMREKEPIVGSTDYGKDEDSAEALLKKHEALMSDLSAYGSSIQAL 949
           QQ   +  + E+WM  +EP++    +G+  + AE +L++H+     ++A    + AL
Sbjct: 721 QQLRHEMEQIEAWMNLREPLLKEKKFGESIEGAEEMLRRHD*F*KTVTAQEDRVNAL 551

 Score = 38.1 bits (87), Expect = 0.051,   Method: Compositional matrix adjust.
 Identities = 27/103 (26%), Positives = 50/103 (48%)
 Frame = -3

Query: 741 ARQFQDAGHFDAENIKKKQEALVARYEALKEPMVARKQKLADSLRLQQLFRDVEDEETWI 800
            R F   GHF ++ I++K + L    E L   +  R++    +L  QQL  ++E  E W+
Sbjct: 859 GRSFIANGHFLSKEIEEKIKQLDQSLEGLIRNLEHRRKLHQQNLEAQQLRHEMEQIEAWM 680

Query: 801 REKEPIAASTNRGKDLIGVQNLLKKHQALQAEIAGHEPRIKAV 843
             +EP+      G+ + G + +L++H      +   E R+ A+
Sbjct: 679 NLREPLLKEKKFGESIEGAEEMLRRHD*F*KTVTAQEDRVNAL 551

 Score = 34.7 bits (78), Expect = 0.54,   Method: Compositional matrix adjust.
 Identities = 16/59 (27%), Positives = 32/59 (54%)
 Frame = -3

Query: 256 EVQRFNRDVDETIGWIKEKEQLMASDDFGRDLASVQALLRKHEGLERDLAALEDKVKAL 314
           E Q+   ++++   W+  +E L+    FG  +   + +LR+H+   + + A ED+V AL
Sbjct: 727 EAQQLRHEMEQIEAWMNLREPLLKEKKFGESIEGAEEMLRRHD*F*KTVTAQEDRVNAL 551
>26578
          Length = 430

 Score = 61.6 bits (148), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 42/130 (32%), Positives = 67/130 (51%), Gaps = 1/130 (0%)
 Frame = +1

Query: 140 EKGIKLLQAQKLVQYLRECEDVMDWINDKEAIVTSEELGQDLEHVEVLQKKFEEFQTDL- 198
           E+  KL +  KL    RE  D++ WI +K  +  S + GQD EHV +L+++F+EF  D  
Sbjct: 1   ERRGKLEEVFKLYTLHREIYDLLQWIAEKSLVAGSNDPGQDYEHVSMLKEQFKEFARDTE 180

Query: 199 AAHEERVNEVSQFAAKLIQEQHPEEELIKTKQDEVNAAWQRLKGLALQRQGKLFGAAEVQ 258
           +  +ERV   ++   +LI   H +   I   +D VN AW  L  L   R   L  + E+ 
Sbjct: 181 SMGQERVASANEICDQLIALDHSDSASIAEWKDNVNEAWADLLELIDTRTQLLQSSWELH 360

Query: 259 RFNRDVDETI 268
           +F  +  +T+
Sbjct: 361 KFLYECKDTL 390

 Score = 50.4 bits (119), Expect = 8e-06,   Method: Compositional matrix adjust.
 Identities = 38/131 (29%), Positives = 65/131 (49%), Gaps = 2/131 (1%)
 Frame = +1

Query: 1204 ERSQLLGSAHEVQRFHRDADETKEWIEEKNQALNTDNYGHDLASVQALQRKHEGFERDLA 1263
            ER   L    ++   HR+  +  +WI EK+    +++ G D   V  L+ + + F RD  
Sbjct: 1    ERRGKLEEVFKLYTLHREIYDLLQWIAEKSLVAGSNDPGQDYEHVSMLKEQFKEFARDTE 180

Query: 1264 ALG-DKVNSLGETAQRLIQ-SHPESAEDLKEKCTELNQAWTSLGKRADQRKAKLGDSHDL 1321
            ++G ++V S  E   +LI   H +SA  + E    +N+AW  L +  D R   L  S +L
Sbjct: 181  SMGQERVASANEICDQLIALDHSDSA-SIAEWKDNVNEAWADLLELIDTRTQLLQSSWEL 357

Query: 1322 QRFLSDFRDLM 1332
             +FL + +D +
Sbjct: 358  HKFLYECKDTL 390

 Score = 48.1 bits (113), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 31/116 (26%), Positives = 60/116 (51%), Gaps = 1/116 (0%)
 Frame = +1

Query: 1416 QRRMMLDHCLELQLFHRDCEQAENWMAAREAFLNTEDKGDSLDSVEALIKKHEDFDKAI- 1474
            +RR  L+   +L   HR+      W+A +     + D G   + V  L ++ ++F +   
Sbjct: 1    ERRGKLEEVFKLYTLHREIYDLLQWIAEKSLVAGSNDPGQDYEHVSMLKEQFKEFARDTE 180

Query: 1475 NVQEEKIAALQAFADQLIAVDHYAKGDIANRRNEVLDRWRRLKAQMIEKRSKLGES 1530
            ++ +E++A+     DQLIA+DH     IA  ++ V + W  L  ++I+ R++L +S
Sbjct: 181  SMGQERVASANEICDQLIALDHSDSASIAEWKDNVNEAWADL-LELIDTRTQLLQS 345

 Score = 44.7 bits (104), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 41/168 (24%), Positives = 67/168 (39%), Gaps = 1/168 (0%)
 Frame = +1

Query: 1063 RKGMLEKSCKKFMLFREANELQQWITEKEAALTNEEVGADLEQVEVXXXXXXXXXXXXXA 1122
            R+G LE+  K + L RE  +L QWI EK     + + G D E V +             +
Sbjct: 4    RRGKLEEVFKLYTLHREIYDLLQWIAEKSLVAGSNDPGQDYEHVSMLKEQFKEFARDTES 183

Query: 1123 -NESRLKDINKVAEDLESEGLMXXXXXXXXXXXXYGAMPRDEADSKTASPWKSARLMVHT 1181
              + R+   N++ + L                     +  D +DS + + WK        
Sbjct: 184  MGQERVASANEICDQL---------------------IALDHSDSASIAEWKD------- 279

Query: 1182 VATFNSIKELNERWRSLQQLAEERSQLLGSAHEVQRFHRDADETKEWI 1229
                     +NE W  L +L + R+QLL S+ E+ +F  +  +T E I
Sbjct: 280  --------NVNEAWADLLELIDTRTQLLQSSWELHKFLYECKDTLERI 399

 Score = 41.6 bits (96), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 32/128 (25%), Positives = 58/128 (45%), Gaps = 1/128 (0%)
 Frame = +1

Query: 1634 EKSQKLKEANKQQNFNTGIKDFDFWLSEVEALLASEDYGKDLASVNNLLKKHQLLEADI- 1692
            E+  KL+E  K    +  I D   W++E   +  S D G+D   V+ L ++ +    D  
Sbjct: 1    ERRGKLEEVFKLYTLHREIYDLLQWIAEKSLVAGSNDPGQDYEHVSMLKEQFKEFARDTE 180

Query: 1693 SAHEDRLKDLNSQADSLMTSSAFDTSQVKEKRDTINGRFQKIKSMATSRRAKLSESHRLH 1752
            S  ++R+   N   D L+     D++ + E +D +N  +  +  +  +R   L  S  LH
Sbjct: 181  SMGQERVASANEICDQLIALDHSDSASIAEWKDNVNEAWADLLELIDTRTQLLQSSWELH 360

Query: 1753 QFFRDMDD 1760
            +F  +  D
Sbjct: 361  KFLYECKD 384

 Score = 40.0 bits (92), Expect = 0.012,   Method: Compositional matrix adjust.
 Identities = 35/125 (28%), Positives = 55/125 (44%), Gaps = 4/125 (3%)
 Frame = +1

Query: 1741 RRAKLSESHRLHQFFRDMDDEESWIKEKKLLVSSEDYGRDLTGVQNLRKKHKRL--EAEL 1798
            RR KL E  +L+   R++ D   WI EK L+  S D G+D   V  L+++ K    + E 
Sbjct: 4    RRGKLEEVFKLYTLHREIYDLLQWIAEKSLVAGSNDPGQDYEHVSMLKEQFKEFARDTES 183

Query: 1799 AAHEPAIQG--VLDTGKKLSDDNTIGQEEIQQRLAQFVEHWKELKQLAAARGQRLEESLE 1856
               E       + D    L   ++    E +  +    E W +L +L   R Q L+ S E
Sbjct: 184  MGQERVASANEICDQLIALDHSDSASIAEWKDNVN---EAWADLLELIDTRTQLLQSSWE 354

Query: 1857 YQQFV 1861
              +F+
Sbjct: 355  LHKFL 369

 Score = 37.7 bits (86), Expect = 0.051,   Method: Compositional matrix adjust.
 Identities = 30/128 (23%), Positives = 61/128 (47%), Gaps = 1/128 (0%)
 Frame = +1

Query: 246 QRQGKLFGAAEVQRFNRDVDETIGWIKEKEQLMASDDFGRDLASVQALLRKHEGLERDLA 305
           +R+GKL    ++   +R++ + + WI EK  +  S+D G+D   V  L  + +   RD  
Sbjct: 1   ERRGKLEEVFKLYTLHREIYDLLQWIAEKSLVAGSNDPGQDYEHVSMLKEQFKEFARDTE 180

Query: 306 AL-EDKVKALCAEADRLQQSHPLSASQIQVKREELITNWEQIRTLAAERHARLDDSYRLQ 364
           ++ +++V +     D+L       ++ I   ++ +   W  +  L   R   L  S+ L 
Sbjct: 181 SMGQERVASANEICDQLIALDHSDSASIAEWKDNVNEAWADLLELIDTRTQLLQSSWELH 360

Query: 365 RFLADFRD 372
           +FL + +D
Sbjct: 361 KFLYECKD 384

 Score = 37.4 bits (85), Expect = 0.076,   Method: Compositional matrix adjust.
 Identities = 30/113 (26%), Positives = 52/113 (46%)
 Frame = +1

Query: 1952 QRKAKLDENSAFLQFNWKADVVESWIGEKENSLKTDDYGRDLSSVQTLLTKQETFDAGLQ 2011
            +R+ KL+E       + +   +  WI EK     ++D G+D   V  L  + + F    +
Sbjct: 1    ERRGKLEEVFKLYTLHREIYDLLQWIAEKSLVAGSNDPGQDYEHVSMLKEQFKEFARDTE 180

Query: 2012 AFQQEGIANITALKDQLLAAKHIQSKAIEARHASLMKRWTQLLANSATRKKKL 2064
            +  QE +A+   + DQL+A  H  S +I     ++ + W  LL    TR + L
Sbjct: 181  SMGQERVASANEICDQLIALDHSDSASIAEWKDNVNEAWADLLELIDTRTQLL 339

 Score = 36.2 bits (82), Expect = 0.18,   Method: Compositional matrix adjust.
 Identities = 32/130 (24%), Positives = 58/130 (44%), Gaps = 3/130 (2%)
 Frame = +1

Query: 776 RKQKLADSLRLQQLFRDVEDEETWIREKEPIAASTNRGKDLIGVQNLLK---KHQALQAE 832
           R+ KL +  +L  L R++ D   WI EK  +A S + G+D   V ++LK   K  A   E
Sbjct: 4   RRGKLEEVFKLYTLHREIYDLLQWIAEKSLVAGSNDPGQDYEHV-SMLKEQFKEFARDTE 180

Query: 833 IAGHEPRIKAVTQKGNAMVEEGHFAAEDVKAKLSELNQKWEALKAKASQRRQDLEDSLQA 892
             G E R+ +  +  + ++   H  +  +      +N+ W  L      R Q L+ S + 
Sbjct: 181 SMGQE-RVASANEICDQLIALDHSDSASIAEWKDNVNEAWADLLELIDTRTQLLQSSWEL 357

Query: 893 QQYFADANEA 902
            ++  +  + 
Sbjct: 358 HKFLYECKDT 387

 Score = 33.9 bits (76), Expect = 0.79,   Method: Compositional matrix adjust.
 Identities = 32/133 (24%), Positives = 66/133 (49%), Gaps = 2/133 (1%)
 Frame = +1

Query: 36  RRQKLEDSYRFQFFQRDAEELEKWIQEKLQVA-SDENYKDPTNLQGKLQKHQAFEAEVQA 94
           RR KLE+ ++     R+  +L +WI EK  VA S++  +D  ++    ++ + F  + ++
Sbjct: 4   RRGKLEEVFKLYTLHREIYDLLQWIAEKSLVAGSNDPGQDYEHVSMLKEQFKEFARDTES 183

Query: 95  -NSGAIVKLDETGNLMISEGHFASETIRTRLMELHRQWELLLEKMREKGIKLLQAQKLVQ 153
                +   +E  + +I+  H  S +I      ++  W  LLE +  +   L  + +L +
Sbjct: 184 MGQERVASANEICDQLIALDHSDSASIAEWKDNVNEAWADLLELIDTRTQLLQSSWELHK 363

Query: 154 YLRECEDVMDWIN 166
           +L EC+D ++ I 
Sbjct: 364 FLYECKDTLERIT 402
>17567
          Length = 448

 Score = 60.8 bits (146), Expect = 6e-09,   Method: Compositional matrix adjust.
 Identities = 33/122 (27%), Positives = 66/122 (54%)
 Frame = -3

Query: 1659 LSEVEALLASEDYGKDLASVNNLLKKHQLLEADISAHEDRLKDLNSQADSLMTSSAFDTS 1718
            L EV++ +  EDYGK L +  ++L++H L EA + A   R++ LN ++      S     
Sbjct: 350  LKEVQSKVVGEDYGKHLQATQDMLEQHSLQEAQLQALTRRVRKLNRKSQGAQEQS----- 186

Query: 1719 QVKEKRDTINGRFQKIKSMATSRRAKLSESHRLHQFFRDMDDEESWIKEKKLLVSSEDYG 1778
             + ++ + +N +   +++ +  RR  L  + + +QF +D ++E+ W+ E+   V S   G
Sbjct: 185  -LDKRLEALNAQLNNVQAQSDKRRQGLETAQQYYQFLQDTEEEDRWVGERIDAVRSPSLG 9

Query: 1779 RD 1780
            +D
Sbjct: 8    KD 3

 Score = 56.6 bits (135), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 40/154 (25%), Positives = 76/154 (49%)
 Frame = -3

Query: 768 ALKEPMVARKQKLADSLRLQQLFRDVEDEETWIREKEPIAASTNRGKDLIGVQNLLKKHQ 827
           AL   + +RK  L+    L  +FR++E  +  ++E +      + GK L   Q++L++H 
Sbjct: 446 ALLAKLESRKSTLSGYNNLMAMFREIESIQEELKEVQSKVVGEDYGKHLQATQDMLEQHS 267

Query: 828 ALQAEIAGHEPRIKAVTQKGNAMVEEGHFAAEDVKAKLSELNQKWEALKAKASQRRQDLE 887
             +A++     R++ + +K     E+       +  +L  LN +   ++A++ +RRQ LE
Sbjct: 266 LQEAQLQALTRRVRKLNRKSQGAQEQS------LDKRLEALNAQLNNVQAQSDKRRQGLE 105

Query: 888 DSLQAQQYFADANEAESWMREKEPIVGSTDYGKD 921
            + Q  Q+  D  E + W+ E+   V S   GKD
Sbjct: 104 TAQQYYQFLQDTEEEDRWVGERIDAVRSPSLGKD 3

 Score = 55.8 bits (133), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 42/146 (28%), Positives = 75/146 (51%), Gaps = 1/146 (0%)
 Frame = -3

Query: 1740 SRRAKLSESHRLHQFFRDMDDEESWIKEKKLLVSSEDYGRDLTGVQNLRKKHKRLEAELA 1799
            SR++ LS  + L   FR+++  +  +KE +  V  EDYG+ L   Q++ ++H   EA+L 
Sbjct: 425  SRKSTLSGYNNLMAMFREIESIQEELKEVQSKVVGEDYGKHLQATQDMLEQHSLQEAQLQ 246

Query: 1800 AHEPAIQGVLDTGKKLSDDNTIGQEE-IQQRLAQFVEHWKELKQLAAARGQRLEESLEYQ 1858
            A    +       +KL+  +   QE+ + +RL         ++  +  R Q LE + +Y 
Sbjct: 245  ALTRRV-------RKLNRKSQGAQEQSLDKRLEALNAQLNNVQAQSDKRRQGLETAQQYY 87

Query: 1859 QFVANVEEEEAWINEKMTLVASEDYG 1884
            QF+ + EEE+ W+ E++  V S   G
Sbjct: 86   QFLQDTEEEDRWVGERIDAVRSPSLG 9

 Score = 53.1 bits (126), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 37/131 (28%), Positives = 70/131 (53%)
 Frame = -3

Query: 685 RNVEDIELWLYEVEGHLASDDYGKDLTNVQNLQKKHALLEADVAAHQDRIDGITIQARQF 744
           R +E I+  L EV+  +  +DYGK L   Q++ ++H+L EA + A   R+  +  +++  
Sbjct: 377 REIESIQEELKEVQSKVVGEDYGKHLQATQDMLEQHSLQEAQLQALTRRVRKLNRKSQGA 198

Query: 745 QDAGHFDAENIKKKQEALVARYEALKEPMVARKQKLADSLRLQQLFRDVEDEETWIREKE 804
           Q+      +++ K+ EAL A+   ++     R+Q L  + +  Q  +D E+E+ W+ E+ 
Sbjct: 197 QE------QSLDKRLEALNAQLNNVQAQSDKRRQGLETAQQYYQFLQDTEEEDRWVGERI 36

Query: 805 PIAASTNRGKD 815
               S + GKD
Sbjct: 35  DAVRSPSLGKD 3

 Score = 48.1 bits (113), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 29/132 (21%), Positives = 66/132 (50%)
 Frame = -3

Query: 1861 VANVEEEEAWINEKMTLVASEDYGDTLAAIQGLLKKHEAFETDFTVHKDRVNDVCTNGQD 1920
            + +++EE   + E  + V  EDYG  L A Q +L++H   E        RV  +    Q 
Sbjct: 371  IESIQEE---LKEVQSKVVGEDYGKHLQATQDMLEQHSLQEAQLQALTRRVRKLNRKSQ- 204

Query: 1921 LIKKNNHHEENISSKMKGLNGKVSDLEKAAAQRKAKLDENSAFLQFNWKADVVESWIGEK 1980
                    E+++  +++ LN ++++++  + +R+  L+    + QF    +  + W+GE+
Sbjct: 203  -----GAQEQSLDKRLEALNAQLNNVQAQSDKRRQGLETAQQYYQFLQDTEEEDRWVGER 39

Query: 1981 ENSLKTDDYGRD 1992
             +++++   G+D
Sbjct: 38   IDAVRSPSLGKD 3
>14594
          Length = 1014

 Score = 58.2 bits (139), Expect = 4e-08,   Method: Compositional matrix adjust.
 Identities = 32/115 (27%), Positives = 60/115 (52%)
 Frame = +3

Query: 2326 VTEEALKEFSMMFKHFDKDKSGRLNHQEFKSCLRSLGYDLPMVEEGEPDPEFEAILDTVD 2385
            +T+E + EF   F  FDKD  G +   E  + +RSLG       +   + E + +++ VD
Sbjct: 423  LTDEQVAEFKEAFSLFDKDGDGTITTSELGTVMRSLG-------QNPTENELQDMINEVD 581

Query: 2386 PNRDGHVSLQEYMAFMISRETENVKSSEEIESAFRALSSEGKPYVTKEELYQNLT 2440
             + +G +  +E++  M++R+ ++    EE+  AFR    +G  Y++  EL   +T
Sbjct: 582  ADGNGTIDFEEFLH-MMARKMKDTDCEEELREAFRVFDKDGNGYISAAELRHVMT 743
>29687
          Length = 434

 Score = 47.4 bits (111), Expect = 7e-05,   Method: Composition-based stats.
 Identities = 32/90 (35%), Positives = 51/90 (56%), Gaps = 1/90 (1%)
 Frame = -2

Query: 964  DDETGKELVLALYDYQEKSPREVTMKKGDILTLLNSTNKDWWKVEV-NDRQGFVPAAYVK 1022
            +D T K  V AL+DY  K   E++  KG I+T ++  +  WW+ +    +Q + P+ YV+
Sbjct: 316  NDFTTKLRVKALHDYNAKREDELSFCKGAIITNVSRQDGGWWRGDYGTKKQHWFPSNYVE 137

Query: 1023 KLDPAQSASRENLLEEQGSIALRQGQIDNQ 1052
            ++D    +S E+L    GS  L+QG ID Q
Sbjct: 136  EIDTQTDSSNESL--ALGS--LQQGSIDVQ 59
>11641
          Length = 2509

 Score = 47.4 bits (111), Expect = 7e-05,   Method: Composition-based stats.
 Identities = 22/71 (30%), Positives = 40/71 (56%), Gaps = 4/71 (5%)
 Frame = -1

Query: 958  QQVAPMDDETGKELVLALYDYQEKSPREVTMKKGDILTLLNST----NKDWWKVEVNDRQ 1013
            Q V+  +  +  E   A + +Q +S  EVT+  G ++ +LN      N +WW V+ +  Q
Sbjct: 871  QPVSSAEPASQHEYYCADFPFQARSSNEVTLFAGQVVVVLNRQDLDGNTEWWLVDADGYQ 692

Query: 1014 GFVPAAYVKKL 1024
            G+ PA+Y++K+
Sbjct: 691  GYAPASYLRKM 659
>29426
          Length = 361

 Score = 47.4 bits (111), Expect = 8e-05,   Method: Compositional matrix adjust.
 Identities = 29/121 (23%), Positives = 54/121 (44%), Gaps = 7/121 (5%)
 Frame = -2

Query: 2105 CNSLEEIKALREAHDAFRSSLSSAQADFNQLAELDRQIKS------FRVASNPYTWF-TM 2157
             ++ EE++ L +AH+ F+++L  A  +++ +  L +++ S           NPYT     
Sbjct: 357  VHTTEEVEGLVDAHEQFKATLGEADKEYSTIVSLSQEVASLGQQYDLTPPDNPYTTLHAQ 178

Query: 2158 EALEETWRNLQXXXXXXXXXXXXXXXXXXXNDKLRQEFAQHANAFHQWIQETRTYLLDGI 2217
            E +   W  ++                   N++LR++FA  AN   QWI+      LD +
Sbjct: 177  EDITNKWSEVRELVPRRDQTLQQEMTRQQNNERLRRQFATKANTVGQWIESQ----LDAV 10

Query: 2218 A 2218
            A
Sbjct: 9    A 7
>16716
          Length = 934

 Score = 44.7 bits (104), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 18/54 (33%), Positives = 27/54 (50%)
 Frame = -1

Query: 968  GKELVLALYDYQEKSPREVTMKKGDILTLLNSTNKDWWKVEVNDRQGFVPAAYV 1021
            G    +ALYDYQ     E+T    D++T +   +  WW+   + + G  PA YV
Sbjct: 475  GGSTAIALYDYQAADDDELTFDPDDVITDIEMIDDGWWRGSCHGKNGLFPANYV 314
>20131
          Length = 574

 Score = 43.5 bits (101), Expect = 0.001,   Method: Composition-based stats.
 Identities = 21/78 (26%), Positives = 43/78 (55%), Gaps = 2/78 (2%)
 Frame = -2

Query: 958  QQVAPMDDETGKELVLALYDYQEKSPREVTMKKGDILTLLNSTNKDWWKVEVNDRQGFVP 1017
            Q++    D    E  +A+Y Y      ++T  +GD++ L+   ++DWW   + ++ G  P
Sbjct: 516  QEIHQRLDRKEGEYYVAMYSYVSGETADLTFNEGDMI-LVTKKDEDWWTGTLGEKTGMFP 340

Query: 1018 AAYVKKLD--PAQSASRE 1033
            + YVKK++  P Q ++++
Sbjct: 339  STYVKKVEIQPGQKSAKK 286
>25483
          Length = 438

 Score = 43.5 bits (101), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 32/119 (26%), Positives = 57/119 (47%), Gaps = 4/119 (3%)
 Frame = -2

Query: 215 LIQEQHPEEELIKTKQDEVNAAWQRLKGLALQRQ---GKLF-GAAEVQRFNRDVDETIGW 270
           L Q   P+ +L++ +QD +N  W+ L     +RQ   G++  G+     F  D+DE   W
Sbjct: 383 LRQMSAPQADLLRQRQDSINQRWKALCSEVFERQKYAGRVEEGSTRTSDFTDDMDELFFW 204

Query: 271 IKEKEQLMASDDFGRDLASVQALLRKHEGLERDLAALEDKVKALCAEADRLQQSHPLSA 329
           I E E ++AS     +   +  LL K +  + D+A+ +  + A+     RL  S  ++ 
Sbjct: 203 IDETENILAS-TLKLETQYLSDLLEKVKDRQEDVASRQQNLTAIQTNGTRLVLSDSMTP 30

 Score = 31.6 bits (70), Expect = 4.4,   Method: Compositional matrix adjust.
 Identities = 30/114 (26%), Positives = 56/114 (49%), Gaps = 5/114 (4%)
 Frame = -2

Query: 752 AENIKKKQEALVARYEALKEPMVARKQKLAD-----SLRLQQLFRDVEDEETWIREKEPI 806
           A+ ++++Q+++  R++AL   +  R QK A      S R      D+++   WI E E I
Sbjct: 359 ADLLRQRQDSINQRWKALCSEVFER-QKYAGRVEEGSTRTSDFTDDMDELFFWIDETENI 183

Query: 807 AASTNRGKDLIGVQNLLKKHQALQAEIAGHEPRIKAVTQKGNAMVEEGHFAAED 860
            AST + +    + +LL+K +  Q ++A  +  + A+   G  +V       ED
Sbjct: 182 LASTLKLETQY-LSDLLEKVKDRQEDVASRQQNLTAIQTNGTRLVLSDSMTPED 24

 Score = 30.4 bits (67), Expect = 8.3,   Method: Compositional matrix adjust.
 Identities = 31/133 (23%), Positives = 61/133 (45%), Gaps = 6/133 (4%)
 Frame = -2

Query: 1269 VNSLGETAQRLIQ--SHPESAEDLKEKCTELNQAWTSLGKRADQRKAKLGDSHDLQRFLS 1326
            VNS+      +++  S P+ A+ L+++   +NQ W +L     +R+   G   +     S
Sbjct: 416  VNSMNSAGNEMLRQMSAPQ-ADLLRQRQDSINQRWKALCSEVFERQKYAGRVEEGSTRTS 240

Query: 1327 DFRD----LMSWINGIRGLVSSDELAKDVTGAEALLERHQEHRTEIDARAGTFQAFEQFG 1382
            DF D    L  WI+    +++S  L  +      LLE+ ++ + ++ +R     A +  G
Sbjct: 239  DFTDDMDELFFWIDETENILAS-TLKLETQYLSDLLEKVKDRQEDVASRQQNLTAIQTNG 63

Query: 1383 QQLLAHGHYASPE 1395
             +L+      +PE
Sbjct: 62   TRLVLSDSM-TPE 27
>17286
          Length = 489

 Score = 42.4 bits (98), Expect = 0.002,   Method: Composition-based stats.
 Identities = 16/53 (30%), Positives = 36/53 (67%)
 Frame = +3

Query: 974  ALYDYQEKSPREVTMKKGDILTLLNSTNKDWWKVEVNDRQGFVPAAYVKKLDP 1026
            A+YD+  +S  E+  ++GD++TL++  +++W++  V+ + G+ P  YV+ + P
Sbjct: 36   AIYDFLPESDGELGFQEGDMITLISQVDENWFEGSVHGKVGYFPINYVEVVVP 194
>13664
          Length = 507

 Score = 42.4 bits (98), Expect = 0.002,   Method: Composition-based stats.
 Identities = 20/56 (35%), Positives = 35/56 (62%), Gaps = 1/56 (1%)
 Frame = +2

Query: 961  APMDDETGKELVLALYDYQEKSPREVTMKKGDILTLLNSTNKDWWKVEVND-RQGF 1015
            +P+      + V+ALYDY+ +   E+T+  GD++ LL+  ++ WW  E+ D +QGF
Sbjct: 338  SPLGSTRKPKKVVALYDYKAQRSDELTILSGDVIMLLHKDSESWWMGELLDGQQGF 505
>14945
          Length = 1337

 Score = 42.0 bits (97), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 31/105 (29%), Positives = 51/105 (48%), Gaps = 4/105 (3%)
 Frame = +1

Query: 2320 ARNTTG----VTEEALKEFSMMFKHFDKDKSGRLNHQEFKSCLRSLGYDLPMVEEGEPDP 2375
             R  TG    +TEE  +E    F  FD D SG ++ +E K  +R+LG++ P  E      
Sbjct: 64   GRKKTGPKCELTEEQKQEIREAFDLFDADGSGTIDAKELKVAMRALGFE-PKKE------ 222

Query: 2376 EFEAILDTVDPNRDGHVSLQEYMAFMISRETENVKSSEEIESAFR 2420
            E + ++  +D    G +   +++  M  + +E   + EEI  AFR
Sbjct: 223  EIKKMIAEIDKEGTGTIDFNDFLTIMTQKMSEK-DAKEEILKAFR 354
>22063
          Length = 688

 Score = 41.6 bits (96), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 31/105 (29%), Positives = 51/105 (48%), Gaps = 4/105 (3%)
 Frame = +3

Query: 2320 ARNTTG----VTEEALKEFSMMFKHFDKDKSGRLNHQEFKSCLRSLGYDLPMVEEGEPDP 2375
             R  TG    +TEE  +E    F  FD D SG ++ +E K  +R+LG++ P  E      
Sbjct: 123  GRKKTGPKCELTEEQKQEIREAFDLFDADGSGTIDAKELKVAMRALGFE-PKKE------ 281

Query: 2376 EFEAILDTVDPNRDGHVSLQEYMAFMISRETENVKSSEEIESAFR 2420
            E + ++  +D    G +   +++  M  + +E   + EEI  AFR
Sbjct: 282  EIKKMIAEIDKEGTGTIDFNDFLTIMTQKMSEK-DAKEEILKAFR 413
>21187
          Length = 1206

 Score = 40.0 bits (92), Expect = 0.011,   Method: Composition-based stats.
 Identities = 26/90 (28%), Positives = 48/90 (53%), Gaps = 9/90 (10%)
 Frame = +2

Query: 974  ALYDYQEKSPREVTMKKGDILTLLNST---NKDWWKVEVNDRQGFVPAAYVKKL-----D 1025
            A+  Y   SP  +T+ +GDI+ + + +     D W  EVN R+G+ P A+VK+      +
Sbjct: 137  AIGRYPASSPLYLTLNRGDIVEIKSKSAGNRPDLWGGEVNGRKGYFPKAFVKEFHINIHN 316

Query: 1026 PA-QSASRENLLEEQGSIALRQGQIDNQYQ 1054
            P  +  + ENL  ++ + A ++ +  +Q Q
Sbjct: 317  PMFEVPTEENLWSKRPAPAQQEQRPPHQDQ 406
>17613
          Length = 1108

 Score = 40.0 bits (92), Expect = 0.012,   Method: Compositional matrix adjust.
 Identities = 21/55 (38%), Positives = 30/55 (54%), Gaps = 1/55 (1%)
 Frame = +2

Query: 1858 QQFVANVEEEEAWINEKMTLVASEDYGDT-LAAIQGLLKKHEAFETDFTVHKDRV 1911
            Q+F    E  E W   K  ++ S D+    L  ++ + KKHEAFE+D   H+DRV
Sbjct: 938  QKFRHKCEIHEEWSQGKEDMLQSRDFKQCRLNELKAMKKKHEAFESDLAAHQDRV 1102

 Score = 36.2 bits (82), Expect = 0.17,   Method: Compositional matrix adjust.
 Identities = 21/56 (37%), Positives = 32/56 (57%), Gaps = 1/56 (1%)
 Frame = +2

Query: 681 QQFNRNVEDIELWLYEVEGHLASDDYGK-DLTNVQNLQKKHALLEADVAAHQDRID 735
           Q+F    E  E W    E  L S D+ +  L  ++ ++KKH   E+D+AAHQDR++
Sbjct: 938 QKFRHKCEIHEEWSQGKEDMLQSRDFKQCRLNELKAMKKKHEAFESDLAAHQDRVE 1105

 Score = 36.2 bits (82), Expect = 0.18,   Method: Compositional matrix adjust.
 Identities = 22/57 (38%), Positives = 35/57 (61%), Gaps = 2/57 (3%)
 Frame = +2

Query: 151 LVQYLR-ECEDVMDWINDKEAIVTSEELGQ-DLEHVEVLQKKFEEFQTDLAAHEERV 205
           L Q  R +CE   +W   KE ++ S +  Q  L  ++ ++KK E F++DLAAH++RV
Sbjct: 932 LAQKFRHKCEIHEEWSQGKEDMLQSRDFKQCRLNELKAMKKKHEAFESDLAAHQDRV 1102

 Score = 35.4 bits (80), Expect = 0.28,   Method: Compositional matrix adjust.
 Identities = 20/58 (34%), Positives = 33/58 (56%), Gaps = 1/58 (1%)
 Frame = +2

Query: 1213 HEVQRFHRDADETKEWIEEKNQALNTDNYGH-DLASVQALQRKHEGFERDLAALGDKV 1269
            H  Q+F    +  +EW + K   L + ++    L  ++A+++KHE FE DLAA  D+V
Sbjct: 929  HLAQKFRHKCEIHEEWSQGKEDMLQSRDFKQCRLNELKAMKKKHEAFESDLAAHQDRV 1102

 Score = 34.3 bits (77), Expect = 0.67,   Method: Compositional matrix adjust.
 Identities = 20/56 (35%), Positives = 32/56 (57%), Gaps = 1/56 (1%)
 Frame = +2

Query: 257 VQRFNRDVDETIGWIKEKEQLMASDDFGR-DLASVQALLRKHEGLERDLAALEDKV 311
            Q+F    +    W + KE ++ S DF +  L  ++A+ +KHE  E DLAA +D+V
Sbjct: 935 AQKFRHKCEIHEEWSQGKEDMLQSRDFKQCRLNELKAMKKKHEAFESDLAAHQDRV 1102

 Score = 33.5 bits (75), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 22/68 (32%), Positives = 35/68 (51%), Gaps = 1/68 (1%)
 Frame = +2

Query: 1415 VQRRMMLDHCLELQLFHRDCEQAENWMAAREAFLNTED-KGDSLDSVEALIKKHEDFDKA 1473
            +QR   LDH    Q F   CE  E W   +E  L + D K   L+ ++A+ KKHE F+  
Sbjct: 905  LQRLERLDHLA--QKFRHKCEIHEEWSQGKEDMLQSRDFKQCRLNELKAMKKKHEAFESD 1078

Query: 1474 INVQEEKI 1481
            +   ++++
Sbjct: 1079 LAAHQDRV 1102
>19469
          Length = 428

 Score = 39.7 bits (91), Expect = 0.016,   Method: Composition-based stats.
 Identities = 19/57 (33%), Positives = 29/57 (50%), Gaps = 3/57 (5%)
 Frame = -1

Query: 971  LVLALYDYQEKSPREVTMKKGDILTLLNSTN---KDWWKVEVNDRQGFVPAAYVKKL 1024
            L  ALYD   ++P E+  ++GD++T+L         WW   +  RQG  P   +K L
Sbjct: 362  LAKALYDNIAETPDELAFRRGDVITILEQDTAGLDGWWLCSLRGRQGIAPGNRLKIL 192
>12324
          Length = 946

 Score = 38.5 bits (88), Expect = 0.038,   Method: Composition-based stats.
 Identities = 14/53 (26%), Positives = 30/53 (56%)
 Frame = +3

Query: 970  ELVLALYDYQEKSPREVTMKKGDILTLLNSTNKDWWKVEVNDRQGFVPAAYVK 1022
            E V+A+YDY+ +   E+T  +  ++ ++   +  WW+  ++   G  P+ YV+
Sbjct: 690  EKVVAIYDYEAEKDDELTFSENSVIYVIRKNDDGWWEGVMDGVTGLFPSNYVE 848
>30740
          Length = 488

 Score = 37.7 bits (86), Expect = 0.066,   Method: Composition-based stats.
 Identities = 15/48 (31%), Positives = 27/48 (56%)
 Frame = +2

Query: 969  KELVLALYDYQEKSPREVTMKKGDILTLLNSTNKDWWKVEVNDRQGFV 1016
            +E ++  YD+  + P ++   KGDIL L++   ++WW     D+ G V
Sbjct: 182  REKLMGKYDFSGRDPEDLPFSKGDILELISKDEEEWWTAR--DKHGRV 319
>38338
          Length = 463

 Score = 37.4 bits (85), Expect = 0.081,   Method: Compositional matrix adjust.
 Identities = 25/99 (25%), Positives = 48/99 (48%), Gaps = 2/99 (2%)
 Frame = -2

Query: 2298 QQWDQLDQLGMRMQHNLEQQIQARNTTG--VTEEALKEFSMMFKHFDKDKSGRLNHQEFK 2355
            Q+  + + LG R +  +  Q  +++     +TEE + EF   F  FDKD  G +  +E  
Sbjct: 276  QEPSRSEGLGYRRRVLVHHQTHSKSNMADQLTEEQIAEFKEAFSLFDKDGDGTITTKELG 97

Query: 2356 SCLRSLGYDLPMVEEGEPDPEFEAILDTVDPNRDGHVSL 2394
            + +RSLG       +   + E + +++ VD + +G +  
Sbjct: 96   TVMRSLG-------QNPTEAELQDMINEVDADGNGTIDF 1
>28095
          Length = 597

 Score = 34.7 bits (78), Expect = 0.45,   Method: Composition-based stats.
 Identities = 16/54 (29%), Positives = 28/54 (51%), Gaps = 2/54 (3%)
 Frame = +3

Query: 974  ALYDYQEKSPREVTMKKGDILTLLNSTNKDWW--KVEVNDRQGFVPAAYVKKLD 1025
            A+YDYQ     EV+   GD +      +  W   +VE   + G +P+ YV++++
Sbjct: 270  AMYDYQAADSDEVSFNDGDTIIECQPVDAGWMTGRVERTGQYGMLPSNYVERIN 431
>01494
          Length = 2122

 Score = 34.7 bits (78), Expect = 0.46,   Method: Compositional matrix adjust.
 Identities = 25/90 (27%), Positives = 48/90 (53%), Gaps = 1/90 (1%)
 Frame = +3

Query: 964  DDETGKELVLALYDYQEKSPREVTMKKGDILTLLNSTNKDWWKVEVN-DRQGFVPAAYVK 1022
            +D T K  V AL+DY      E++  KG I+T ++  +  WW+ +    +Q + P+ +V+
Sbjct: 288  NDFTTKLRVKALHDYNANRDDELSFCKGAIITNVSRQDGGWWRGDYGAKKQHWFPSNFVE 467

Query: 1023 KLDPAQSASRENLLEEQGSIALRQGQIDNQ 1052
            +++     + +++    GS  L+QG  D Q
Sbjct: 468  EIETHSDVNSDSM--PLGS--LQQGSFDIQ 545
>20251
          Length = 2203

 Score = 33.1 bits (74), Expect = 1.4,   Method: Composition-based stats.
 Identities = 34/151 (22%), Positives = 62/151 (41%), Gaps = 3/151 (1%)
 Frame = +3

Query: 2328 EEALKEFSMMFKHFDKDKSGRLNHQEFKSCLRSLGYDLPMVEEGEPDPEFEAILDTVDPN 2387
            +  ++EF   F   D+++ G ++ ++    L SLG +             E  LD +   
Sbjct: 147  QSQIQEFKEAFNMIDQNRDGFIDKEDLGDMLASLGKN-----------PTEGQLDEMMNX 293

Query: 2388 RDGHVSLQEYMAFMISRETENVKSSEEIESAFRALSSEGKPYVTKEELYQNLTREQADYC 2447
              G ++   ++  M   +       + I++AF     +GK  + ++ L + LT     + 
Sbjct: 294  APGPINFTMFLT-MFGDKLNGTDPEDVIKNAFACFDEDGKGVIQEDRLRELLTTMGDRFT 470

Query: 2448 VSHMKPYVDGKGRELPTA---FDYVEFTRSL 2475
                   VD   R+ P     FDY+EFTR L
Sbjct: 471  DDE----VDEMFRDAPIKRGNFDYLEFTRIL 551
>17484
          Length = 471

 Score = 32.7 bits (73), Expect = 1.8,   Method: Compositional matrix adjust.
 Identities = 15/55 (27%), Positives = 29/55 (52%)
 Frame = -1

Query: 2341 FDKDKSGRLNHQEFKSCLRSLGYDLPMVEEGEPDPEFEAILDTVDPNRDGHVSLQ 2395
            +D+D +G++   EF+S +R LG+ L        + E E ++   D +  G + L+
Sbjct: 465  YDQDGNGKITRNEFRSVVRMLGHSL-------SEKELEEMMQAADTDASGAIELK 322
>06641
          Length = 726

 Score = 32.3 bits (72), Expect = 2.8,   Method: Compositional matrix adjust.
 Identities = 29/123 (23%), Positives = 53/123 (43%), Gaps = 12/123 (9%)
 Frame = +1

Query: 2332 KEFSMMFKHFDKDKSGRLNHQEFKSCLRSLGYD---------LPMVEEGEPDPEFEAILD 2382
            K+ +  F  FD + +  ++ +E  + +RSLG           L  +EE EP         
Sbjct: 193  KKITDAFDIFDHEANKTVDVREVGTIIRSLGCCPSEAELHDMLAEIEEEEPT-------- 348

Query: 2383 TVDPNRDGHVSLQEYMAFMISRETE---NVKSSEEIESAFRALSSEGKPYVTKEELYQNL 2439
                   G++  ++++  M     E        ++I  AF+ L  EG+ Y+ +EEL + +
Sbjct: 349  -------GYIRFEKFLPMMTKVLMERRYKAVPEDQIVKAFQVLDVEGRGYLLQEELSKYM 507

Query: 2440 TRE 2442
            T E
Sbjct: 508  TEE 516
>03732
          Length = 1114

 Score = 31.6 bits (70), Expect = 3.8,   Method: Composition-based stats.
 Identities = 17/69 (24%), Positives = 32/69 (46%)
 Frame = -1

Query: 2338 FKHFDKDKSGRLNHQEFKSCLRSLGYDLPMVEEGEPDPEFEAILDTVDPNRDGHVSLQEY 2397
            F+ +D+D SG ++  E K+ L   GY L        D  F+ ++   D    G V+  ++
Sbjct: 883  FRSYDRDNSGSIDRNELKNALTGFGYRL-------SDRFFDVLVKKFDRQGKGTVAFDDF 725

Query: 2398 MAFMISRET 2406
            +   +  +T
Sbjct: 724  IQCCVVLQT 698
>11780
          Length = 1713

 Score = 30.8 bits (68), Expect = 7.0,   Method: Composition-based stats.
 Identities = 15/41 (36%), Positives = 26/41 (63%), Gaps = 2/41 (4%)
 Frame = +3

Query: 984  REVTMKKGDILTLLNST-NKDWWKV-EVNDRQGFVPAAYVK 1022
            R    +KGD+L +  +T ++ W+K  + N R+G +PA YV+
Sbjct: 99   RTYPFQKGDLLVIRRATSDRMWYKACDSNGREGMIPANYVQ 221
>11230
          Length = 747

 Score = 30.8 bits (68), Expect = 8.0,   Method: Compositional matrix adjust.
 Identities = 27/104 (25%), Positives = 52/104 (50%), Gaps = 9/104 (8%)
 Frame = +3

Query: 2383 TVDPNRDGHVSLQEYMAFM-ISRETEN-----VKSSEEIESAFRALSSEGKPYVTKEELY 2436
            ++D ++DG + L+EY+A M  +R+ E+     VKS  +    +R L  +GK  +   E+ 
Sbjct: 264  SIDKDKDGLIDLEEYIADMWPNRDNEDEEPDWVKSERKQFDTYRDLDKDGK--LDPSEVK 437

Query: 2437 QNLTREQADYCVSHMKPYV---DGKGRELPTAFDYVEFTRSLFV 2477
            + +  E  D+  +  K  +   DG  ++   ++D +     LFV
Sbjct: 438  RWILPENFDHARAESKHLIFEADGGDKDGKLSYDEILDKYDLFV 569
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|29789050|ref|NP_038880.1| ATP-binding cassette,
sub-family F (GCN20), member 3 [Mus musculus]
         (709 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

03538                                                                 166   4e-41
38795                                                                 159   5e-39
22801                                                                 110   3e-24
24147                                                                  59   6e-09
05764                                                                  54   3e-07
33929                                                                  52   1e-06
01623                                                                  51   1e-06
12308                                                                  45   1e-04
02301                                                                  39   0.007
30281                                                                  36   0.064
19618                                                                  35   0.12 
34156                                                                  33   0.27 
20290                                                                  33   0.57 
01142                                                                  30   3.3  
11314                                                                  30   3.9  
01970                                                                  30   4.4  
18248                                                                  29   5.1  
22529                                                                  29   5.2  
>03538
          Length = 1974

 Score =  166 bits (419), Expect = 4e-41,   Method: Compositional matrix adjust.
 Identities = 83/176 (47%), Positives = 115/176 (65%)
 Frame = -1

Query: 528  GAGKSTMLKLLMGDLSPVRGIRHAHRNLKIGYFSQHHVEQLDLNVSAVELLARKFPGLPE 587
            G GKST+LKLLMGDL P +G +  +  L++G + QH  +QL+L+ S VE L R F  L  
Sbjct: 1971 GVGKSTLLKLLMGDLQPSQGEKRMNHRLRVGKYDQHSADQLNLDESPVEYLKRLFD-LQY 1795

Query: 588  EEYRHQLGRYGISGELAMRPVASLSGGQKSRVAFAQMTMPCPNFYILDEPTNHLDMETIE 647
            ++ R  LGR G++          LSGGQ++RVA A+++   P+  +LDEPTN+LD+E+I+
Sbjct: 1794 QDARKMLGRVGLASHAHTILNRDLSGGQRARVALAELSCRAPDVLVLDEPTNNLDIESID 1615

Query: 648  ALGQALNNFRGGVILVSHDERFIRLVCKELWVCENGSVTRVEGGFDQYRALLQEQF 703
            AL  A+ NF GGVI+VSHDER IR    +LWV E+ ++  V+G FD YR  L E  
Sbjct: 1614 ALADAIKNFTGGVIIVSHDERLIRDTNCQLWVVEDNTINEVDGDFDDYRRELLEAL 1447

 Score = 42.0 bits (97), Expect = 8e-04,   Method: Compositional matrix adjust.
 Identities = 33/155 (21%), Positives = 62/155 (40%), Gaps = 2/155 (1%)
 Frame = -1

Query: 268  ERELSLRIAAGRAEGSEAAQLAEIYGKLEEIEA--DKAPARASVILAGLGFTPKMQQQPT 325
            E+ ++ R+  G+ +   A QL      +E ++   D     A  +L  +G          
Sbjct: 1911 EKRMNHRLRVGKYDQHSADQLNLDESPVEYLKRLFDLQYQDARKMLGRVGLASHAHTILN 1732

Query: 326  REFSGGWXXXXXXXXXXXXXXXXXXXDEPTNMLDVRAILWLENYLQTWPSTILVVSHDRN 385
            R+ SGG                    DEPTN LD+ +I  L + ++ +   +++VSHD  
Sbjct: 1731 RDLSGGQRARVALAELSCRAPDVLVLDEPTNNLDIESIDALADAIKNFTGGVIIVSHDER 1552

Query: 386  FLNAIATDIIHLHSQRLDGYRGDFETFIKSKQERL 420
             +      +  +    ++   GDF+ + +   E L
Sbjct: 1551 LIRDTNCQLWVVEDNTINEVDGDFDDYRRELLEAL 1447
>38795
          Length = 792

 Score =  159 bits (401), Expect = 5e-39,   Method: Compositional matrix adjust.
 Identities = 85/261 (32%), Positives = 139/261 (53%), Gaps = 5/261 (1%)
 Frame = +1

Query: 287 QLAEIYGKLEEIEADKAPARASVILAGLGFTPKMQQQPTREFSGGWXXXXXXXXXXXXXX 346
           +L  +Y +L+E+++ KA A+A  IL GLGF+  MQ    + FSGGW              
Sbjct: 10  RLLAVYDRLDELDSTKALAKAGFILHGLGFSKDMQHTKVKNFSGGWRMRIGLARALYLRP 189

Query: 347 XXXXXDEPTNMLDVRAILWLENYLQTWPSTILVVSHDRNFLNAIATDIIHLHSQRLDGYR 406
                DEPTN LD+ A +WLE  L+ +P  ++++SH ++FLN +   IIH++ ++L  Y 
Sbjct: 190 SLLLLDEPTNHLDLNACVWLEEELKNYPRILVIISHSQDFLNGVCNSIIHMNQKKLQYYG 369

Query: 407 GDFETFIKSKQERLLNXXXXXXXXXXXXXHIQVFIDRFRY-NANRASQVQSXXXXXXXXX 465
           G+++++++++ E L N             H++ +I RF + +A  A Q QS         
Sbjct: 370 GNYDSYVQTRLELLENQAKRYKWEQDQISHMKNYIARFGHGSAKLARQAQSKEKTLKKMV 549

Query: 466 XXXXVDK---ESEVVLKFPDGFEKFSPPILQLDEVDFYYD-PKHSIFSRLSVSADLESRI 521
                +K   +  +   FP       PP++ +  V F Y+  K  I+  L    DL++R+
Sbjct: 550 DGGLTEKVTSDKTLSFYFPS-CGTIPPPVIMVQHVSFRYNETKPYIYQNLDFGIDLDTRV 726

Query: 522 CVVGENGAGKSTMLKLLMGDL 542
            +VG NGAGKST+LKL+ G+L
Sbjct: 727 ALVGPNGAGKSTLLKLISGEL 789

 Score = 55.5 bits (132), Expect = 8e-08,   Method: Compositional matrix adjust.
 Identities = 33/112 (29%), Positives = 55/112 (49%), Gaps = 4/112 (3%)
 Frame = +1

Query: 598 GISGELAMRPVASLSGGQKSRVAFAQMTMPCPNFYILDEPTNHLDMETIEALGQALNNFR 657
           G S ++    V + SGG + R+  A+     P+  +LDEPTNHLD+     L + L N+ 
Sbjct: 94  GFSKDMQHTKVKNFSGGWRMRIGLARALYLRPSLLLLDEPTNHLDLNACVWLEEELKNYP 273

Query: 658 GGVILVSHDERFIRLVCKELWVCENGSVTRVEGGFDQY----RALLQEQFRR 705
             ++++SH + F+  VC  +       +    G +D Y      LL+ Q +R
Sbjct: 274 RILVIISHSQDFLNGVCNSIIHMNQKKLQYYGGNYDSYVQTRLELLENQAKR 429
>22801
          Length = 753

 Score =  110 bits (274), Expect = 3e-24,   Method: Compositional matrix adjust.
 Identities = 49/93 (52%), Positives = 67/93 (72%)
 Frame = -1

Query: 611 LSGGQKSRVAFAQMTMPCPNFYILDEPTNHLDMETIEALGQALNNFRGGVILVSHDERFI 670
           LSGGQ++RVA A+++   P+  +LDEPTN+LD+E+I+AL  A+ NF GGVI+VSHDER I
Sbjct: 732 LSGGQRARVALAELSCRAPDVLVLDEPTNNLDIESIDALADAIKNFTGGVIIVSHDERLI 553

Query: 671 RLVCKELWVCENGSVTRVEGGFDQYRALLQEQF 703
           R    +LWV E+ ++  V+G FD YR  L E  
Sbjct: 552 RDTNCQLWVVEDNTINEVDGDFDDYRRELLEAL 454

 Score = 37.7 bits (86), Expect = 0.016,   Method: Compositional matrix adjust.
 Identities = 22/96 (22%), Positives = 40/96 (41%)
 Frame = -1

Query: 325 TREFSGGWXXXXXXXXXXXXXXXXXXXDEPTNMLDVRAILWLENYLQTWPSTILVVSHDR 384
            R+ SGG                    DEPTN LD+ +I  L + ++ +   +++VSHD 
Sbjct: 741 NRDLSGGQRARVALAELSCRAPDVLVLDEPTNNLDIESIDALADAIKNFTGGVIIVSHDE 562

Query: 385 NFLNAIATDIIHLHSQRLDGYRGDFETFIKSKQERL 420
             +      +  +    ++   GDF+ + +   E L
Sbjct: 561 RLIRDTNCQLWVVEDNTINEVDGDFDDYRRELLEAL 454
>24147
          Length = 394

 Score = 58.9 bits (141), Expect = 6e-09,   Method: Compositional matrix adjust.
 Identities = 28/55 (50%), Positives = 38/55 (69%)
 Frame = +2

Query: 528 GAGKSTMLKLLMGDLSPVRGIRHAHRNLKIGYFSQHHVEQLDLNVSAVELLARKF 582
           G GKST+LKLLMGDL P +G +  +  L++G + QH  +QL+L+ S VE L R F
Sbjct: 2   GVGKSTLLKLLMGDLQPSQGEKRMNHRLRVGKYDQHSADQLNLDESPVEYLKRLF 166
>05764
          Length = 1395

 Score = 53.5 bits (127), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 68/260 (26%), Positives = 111/260 (42%), Gaps = 33/260 (12%)
 Frame = -2

Query: 483  GFEKFSPPILQLDEVDFYYD--PKHSIFSRLSVSADLESRICVVGENGAGKSTMLKLLMG 540
            G  K +   +++++V+F Y   P+  +   +S+         +VG +G GKST++ LL  
Sbjct: 1160 GIRKDAKGNIKVEKVEFCYPTRPEIQVLKGISLEISAGQTAALVGISGCGKSTIISLLQR 981

Query: 541  DLSPVRG--------IRH----AHRNL-----------------KIGYFSQHHVEQLDLN 571
               P +G        +R     A R+L                  I Y  +  V   D+ 
Sbjct: 980  YYDPSKGRLLVDGTDVRDYNITALRSLLSVVSQEPILFDCSIRDNIQYGLESDVPMPDII 801

Query: 572  VSAVELLARKFPGLPEEEYRHQLGRYGISGELAMRPVASLSGGQKSRVAFAQMTMPCPNF 631
             +       +F     + Y  Q+G  G            LSGGQK RVA A+  +  P  
Sbjct: 800  AACKTANIHEFIASLPQGYDTQVGGKG----------TQLSGGQKQRVAIARALVRNPII 651

Query: 632  YILDEPTNHLDMETIEALGQALNNFRGG--VILVSHDERFIRLVCKELWVCENGSVTRVE 689
             +LDE T+ LD E+ + +  AL+N R G   I+++H    I+     ++V ENG +  +E
Sbjct: 650  LLLDEATSALDTESEKLVQAALDNAREGRTCIVIAHRLSTIQ-NADVIFVMENGQI--LE 480

Query: 690  GGFDQYRALLQEQFRREGFL 709
             G   ++ LL  Q    GF+
Sbjct: 479  KG--NHQELLALQGAYAGFV 426
>33929
          Length = 408

 Score = 51.6 bits (122), Expect = 1e-06,   Method: Composition-based stats.
 Identities = 24/63 (38%), Positives = 37/63 (58%)
 Frame = +1

Query: 175 SYDVRIENFDVSFGDRVLLAGADVNLAWGRRYGLVGRNGLGKTTLLKMLATRSLRVPAHI 234
           S D+ I N  + F    LL  + + +  G+RYGL+G NG GK++LL  LA + + +P HI
Sbjct: 193 SRDLHIHNMSILFHGAELLMDSKLEMNVGKRYGLIGLNGCGKSSLLAALANKEVAIPDHI 372

Query: 235 SLL 237
            + 
Sbjct: 373 DIF 381
>01623
          Length = 1414

 Score = 51.2 bits (121), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 66/244 (27%), Positives = 102/244 (41%), Gaps = 30/244 (12%)
 Frame = +3

Query: 492 LQLDEVDFYYD--PKHSIFSRLSVSADLESRICVVGENGAGKSTMLKLLMGDLSPVRG-I 548
           ++  ++ F Y   P  +IF   ++ A       VVG +G+GKST+  LL+    P  G +
Sbjct: 27  IEFRDIHFAYPGRPDVAIFKGFNLQARAGQVTAVVGPSGSGKSTVCGLLLRYYDPNAGQV 206

Query: 549 RHAHRNLK----------IGYFSQH----------HVEQLDLNVSAVEL-----LARKFP 583
               +N+           IG  SQ           ++    +N  AV L      ARK  
Sbjct: 207 MLDGQNIAELDPTWLRSHIGTVSQEPILFSCSVAENIAYGAVNPDAVTLGQIEDAARKAN 386

Query: 584 GLPEEEYRHQLGRYGISGELAMRPVASLSGGQKSRVAFAQMTMPCPNFYILDEPTNHLDM 643
                     LG   + GE  M     LSGGQ+ R+A A+  +  P   +LDE T+ LD 
Sbjct: 387 AF-NFVSTFPLGLDTMVGERGMM----LSGGQRQRIAIARAILKNPEILLLDEATSALDA 551

Query: 644 ETIEALGQALNNFRGG--VILVSHDERFIRLVCKELWVCENGSVTRVEGGFDQYRALLQE 701
           E+   +  AL    GG  VI ++H    I+    ++ V  +G V  + G +    A+   
Sbjct: 552 ESEYLVQDALEKLMGGRTVITIAHRLSTIK-TANQIAVLTDGVVAEM-GSYQDLIAINDG 725

Query: 702 QFRR 705
            FR+
Sbjct: 726 IFRK 737
>12308
          Length = 698

 Score = 45.1 bits (105), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 52/190 (27%), Positives = 83/190 (43%), Gaps = 17/190 (8%)
 Frame = -3

Query: 473 ESEVVLKFPDGFEKFSPPILQLDEVDFYYDPKHSIFSRLSVSADLESRICVVGENGAGKS 532
           ES + LK  +G   F   +++ D+V         +   LS        + V G NG GKS
Sbjct: 594 ESSMKLKPGNGQLIFKDHVIKFDKVPLVTPNGDVLIPELSFEVKAGMNVLVCGPNGCGKS 415

Query: 533 TMLKLLMGDLSPVRG--IRHAHRNLKIGYFSQHHV-------EQLDLNVSAVELLARKFP 583
           ++ ++L G+L P+ G  +    +  K+ Y  Q          +Q+    S  E L +   
Sbjct: 414 SLFRIL-GELWPLFGGSLTKPEKG-KLFYIPQRPYMTVGTLRDQVTYPDSHEEQLRK--- 250

Query: 584 GLPEEEYRHQLGR----YGISGELAMRPVAS----LSGGQKSRVAFAQMTMPCPNFYILD 635
           G  +EE    LG+    Y +  E     V      LSGG+K R+A A++    P F ILD
Sbjct: 249 GTRDEELADILGKVQLDYVLQREGGWDAVQDWMDVLSGGEKQRIAMARLFYHKPQFAILD 70

Query: 636 EPTNHLDMET 645
           E T+ + ++ 
Sbjct: 69  ECTSAVSVDV 40
>02301
          Length = 1098

 Score = 38.9 bits (89), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 21/57 (36%), Positives = 34/57 (59%), Gaps = 2/57 (3%)
 Frame = -2

Query: 611 LSGGQKSRVAFAQMTMPCPNFYILDEPTNHLDMETIEALGQALNNFRGG--VILVSH 665
           LSGGQK R+A A+  +  P   +LDE T+ LD ++   +  A+N    G  V++++H
Sbjct: 686 LSGGQKQRLAIARALVRQPAILLLDEATSALDTQSESLVQSAINECTRGRTVVIIAH 516
>30281
          Length = 821

 Score = 35.8 bits (81), Expect = 0.064,   Method: Compositional matrix adjust.
 Identities = 24/82 (29%), Positives = 44/82 (53%), Gaps = 5/82 (6%)
 Frame = -2

Query: 610 SLSGGQKSRVAFAQMTMPCPNFYILDEPTNHLDMETIEALGQAL---NNFRGGV--ILVS 664
           +LSGGQK RV+ A+      + Y+LD+P + +D    +A+   +   N    G   +LV+
Sbjct: 637 NLSGGQKQRVSVARAVYSDSDVYLLDDPLSAVDSHVGKAIFSKVIGPNGLLRGTTRVLVT 458

Query: 665 HDERFIRLVCKELWVCENGSVT 686
           H   ++ +V  E+ V  +G ++
Sbjct: 457 HGVHWLPMV-DEILVLMDGKIS 395
>19618
          Length = 974

 Score = 34.7 bits (78), Expect = 0.12,   Method: Compositional matrix adjust.
 Identities = 24/70 (34%), Positives = 37/70 (52%), Gaps = 1/70 (1%)
 Frame = +2

Query: 611 LSGGQKSRVAFAQMTMPCPNFYILDEPTNHLDMETIEALGQALNNFRG-GVILVSHDERF 669
           LSGG+K R+A A++    P F ILDE T+ +   +++  G+  +  R  G+ L +   R 
Sbjct: 197 LSGGEKQRIAMARLFYHKPQFAILDECTSAV---SVDVEGKMYSYCREVGITLFTVSHR- 364

Query: 670 IRLVCKELWV 679
                K LWV
Sbjct: 365 -----KSLWV 379
>34156
          Length = 348

 Score = 33.5 bits (75), Expect = 0.27,   Method: Compositional matrix adjust.
 Identities = 24/72 (33%), Positives = 36/72 (50%), Gaps = 1/72 (1%)
 Frame = -1

Query: 510 RLSVSADLESRICVVGENGAGKSTMLK-LLMGDLSPVRGIRHAHRNLKIGYFSQHHVEQL 568
           R SV    E  + VVGE+G GKST++  L + DL P R I  A   ++         + +
Sbjct: 222 RKSVKKGFEFTLMVVGESGLGKSTLVNSLFLTDLYPERHIPSASEKIQ---------QTV 70

Query: 569 DLNVSAVELLAR 580
            ++ S VE+  R
Sbjct: 69  KIDASTVEIEER 34
>20290
          Length = 1550

 Score = 32.7 bits (73), Expect = 0.57,   Method: Compositional matrix adjust.
 Identities = 30/117 (25%), Positives = 50/117 (42%), Gaps = 12/117 (10%)
 Frame = +3

Query: 602  ELAMRPVASLSGGQKSRVAFAQMTMPCPNFYILDEPTNHLDMETIEALGQALNNF----R 657
            E+  + V +LSGG+  RVA         + Y++DEP+ +LD E      + +  +    +
Sbjct: 1020 EIMDQEVQNLSGGELQRVALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRYILHAK 1199

Query: 658  GGVILVSHDERFIRLVCKELWVCE-NGSVTRVE-------GGFDQYRALLQEQFRRE 706
                +V HD      +   + V E   SV  V         G +++  LL   FRR+
Sbjct: 1200 KTGFVVEHDFIMATYLADRVIVIEGQPSVKTVAYSPQSLLNGMNRFLELLGITFRRD 1370
>01142
          Length = 729

 Score = 30.0 bits (66), Expect = 3.3,   Method: Compositional matrix adjust.
 Identities = 29/81 (35%), Positives = 39/81 (48%), Gaps = 5/81 (6%)
 Frame = -1

Query: 610 SLSGGQKSRVAFAQMTMPCPNFYILDEPTNHLDMETIEALGQALNNFRGG-----VILVS 664
           SLS GQ+  V  A+  +      ILDE T  +DMET +AL Q  N  R       V+ ++
Sbjct: 489 SLSVGQRQLVCLARTLLRRSRVLILDEATAAVDMET-DALIQ--NTLRSAFSVCTVLTIA 319

Query: 665 HDERFIRLVCKELWVCENGSV 685
           H    I L   ++ V E G V
Sbjct: 318 HRLHTI-LDYDKIMVLEEGVV 259
>11314
          Length = 852

 Score = 29.6 bits (65), Expect = 3.9,   Method: Compositional matrix adjust.
 Identities = 16/48 (33%), Positives = 24/48 (50%)
 Frame = -2

Query: 554 NLKIGYFSQHHVEQLDLNVSAVELLARKFPGLPEEEYRHQLGRYGISG 601
           N ++G  ++     + L VSA  L A   PG  + +Y HQ+   G SG
Sbjct: 278 NSEVGTHAE*RPTPVSLRVSATLLTAAAHPGPSDGQYTHQVPPLGSSG 135
>01970
          Length = 2861

 Score = 29.6 bits (65), Expect = 4.4,   Method: Compositional matrix adjust.
 Identities = 26/101 (25%), Positives = 45/101 (44%), Gaps = 16/101 (15%)
 Frame = -1

Query: 607  PVASLSGGQ---------KSRVAFAQMTMPCPNFYILDEP----TNHLDMETIEALGQAL 653
            PV  L G +         K R+ F  + + C  +Y L  P    TN  D  TI++  +A+
Sbjct: 2852 PVVELDGDEMTRIIWEKIKDRLIFPYLDVDC-KYYDLGLPYRDQTN--DQVTIDS-AEAI 2685

Query: 654  NNFRGGV---ILVSHDERFIRLVCKELWVCENGSVTRVEGG 691
              +  G+    +   +ER      K++W+  NG++  + GG
Sbjct: 2684 KKYNVGIKCATITPDEERVEEFKLKKMWLSPNGTIRNILGG 2562
>18248
          Length = 466

 Score = 29.3 bits (64), Expect = 5.1,   Method: Composition-based stats.
 Identities = 13/33 (39%), Positives = 20/33 (60%)
 Frame = +1

Query: 610 SLSGGQKSRVAFAQMTMPCPNFYILDEPTNHLD 642
           +LSGG+  RVA         + Y++DEP+ +LD
Sbjct: 367 NLSGGELQRVALTLCLGKPADVYLIDEPSAYLD 465
>22529
          Length = 312

 Score = 29.3 bits (64), Expect = 5.2,   Method: Composition-based stats.
 Identities = 15/39 (38%), Positives = 24/39 (61%), Gaps = 2/39 (5%)
 Frame = +3

Query: 629 PNFYILDEPTNHLDMETIEALGQALNNFRGG--VILVSH 665
           P   +LDE T+ LDME+ + +  AL+  R G   I+++H
Sbjct: 15  PKILLLDEATSALDMESEKTVQDALDKARQGRTTIVIAH 131
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|72534792|ref|NP_084127.2| dynein cytoplasmic 2 heavy
chain 1 [Mus musculus]
         (4306 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

20410                                                                 139   5e-41
28658                                                                 159   3e-38
35288                                                                 149   3e-35
37041                                                                 104   7e-22
14519                                                                  86   3e-16
27572                                                                  84   1e-15
28569                                                                  71   8e-12
12392                                                                  66   3e-10
20622                                                                  65   5e-10
20268                                                                  58   1e-07
32781                                                                  57   2e-07
35960                                                                  54   1e-06
36750                                                                  41   0.010
19780                                                                  37   0.12 
00365                                                                  35   0.52 
39834                                                                  33   2.2  
>20410
          Length = 754

 Score =  139 bits (351), Expect(2) = 5e-41,   Method: Compositional matrix adjust.
 Identities = 65/131 (49%), Positives = 86/131 (65%)
 Frame = -2

Query: 1662 LVYTPLTDKCYLTLTQAMKMGLGGNPYGPAGTGKTESVKALGGLLGRQVLVFNCDEGIDV 1721
            LV TPLTD+CY TL  A+ + LGG P GPAGTGKTE+ K L   + +Q +VFNC +G+D 
Sbjct: 393  LVITPLTDRCYRTLFGALHLHLGGAPEGPAGTGKTETTKDLAKAVAKQCVVFNCSDGLDY 214

Query: 1722 KSMGRIFVGLVKCGAWGCFDEFNRLEEAVLSAVSMQIQTIQDALKNHRTVCELLGKEVEI 1781
             ++G+ F GL  CGAW CFDEFNR++  VLS V+ QI TIQ  + +        G E+ +
Sbjct: 213  IALGKFFKGLASCGAWSCFDEFNRIDLEVLSVVAQQILTIQRGINSGSDTLLFEGTEIRL 34

Query: 1782 NANSGIFITMN 1792
            +    +FITMN
Sbjct: 33   DPTCSVFITMN 1

 Score = 49.7 bits (117), Expect(2) = 5e-41,   Method: Compositional matrix adjust.
 Identities = 23/73 (31%), Positives = 46/73 (63%)
 Frame = -1

Query: 1594 LKLKALILDIIHNIDIVKQLNQVQVHTTDDWAWKKQVRFYMKSDHTCYVQMVDSELQYTY 1653
            + L+A+I+  +H+ D++ +L +VQ+ +  D+ W  Q+R+Y +       +M++S L+Y Y
Sbjct: 595  VTLQAMIVLEVHSRDVLAELCKVQISSELDFNWLSQLRYYWEEGQMI-TRMINSMLKYGY 419

Query: 1654 EYQGNAPKLVYTP 1666
            EY GN+ +  + P
Sbjct: 418  EYLGNSGRTXHHP 380
>28658
          Length = 552

 Score =  159 bits (401), Expect = 3e-38,   Method: Compositional matrix adjust.
 Identities = 88/189 (46%), Positives = 118/189 (62%), Gaps = 4/189 (2%)
 Frame = +3

Query: 1738 GCFDEFNRLEEAVLSAVSMQIQTIQDALKNH--RTVCELLGKEVEINANSGIFITMNPAG 1795
             CFDEFNR++  VLS V+ QI TI  A +    R++ E  G E+ +  +  +FITMNP  
Sbjct: 3    ACFDEFNRIDIEVLSVVAQQITTIHKAQQQRLDRSIFE--GVELVLRPSCAVFITMNP-- 170

Query: 1796 KGYGGRQKLPDNLKQLFRPVAMSRPDNDLIAEVILYSEGFKDAKELGRKLVAIFNLSREL 1855
             GY GR +LPDNLK LFRPVAM  PD  LIAE+ L+S GF DA+ L +K+V  F LS E 
Sbjct: 171  -GYAGRTELPDNLKALFRPVAMMVPDYALIAEISLFSFGFSDARNLAKKIVTTFKLSSEQ 347

Query: 1856 LTPQQHYDWGLRALKTVLRGSGNLLRQLKKNSTKQDVNENHIVVQALRLNTMSKFTFAD- 1914
            L+ Q HYD+G+RA+K+V+  +GNL RQ        D++E  I ++A+R   + KF   D 
Sbjct: 348  LSSQDHYDFGMRAVKSVISAAGNLKRQ------SPDMDEELIALRAIRDVNVPKFLVDDL 509

Query: 1915 -CTRFDALI 1922
             C+    LI
Sbjct: 510  NCSVASCLI 536
>35288
          Length = 370

 Score =  149 bits (375), Expect = 3e-35,   Method: Compositional matrix adjust.
 Identities = 79/122 (64%), Positives = 96/122 (78%)
 Frame = +3

Query: 3178 LDREHRRWNAQVAEIAEELATLPKRAQLAAAFITYLSAAPEGLRKNCLEEWTKAAGLEKF 3237
            LD E++RWN QV E+ +EL  LP RA LAAAFITYL +APE LR+  ++ W  A G+  F
Sbjct: 3    LDGEYQRWNEQVGELTKELQELPLRALLAAAFITYLPSAPEDLRREYMKAWMDAIGIAHF 182

Query: 3238 DLRRFLCTESEQLIWKSEGLPSDDLSIENALVILQSRVCPFLIDPSSQATEWLKTHLKDS 3297
            DLRRFL TESEQL WK+EGLPSD+LS+ENALVILQS   PFL+DPSS+AT WLK H+K++
Sbjct: 183  DLRRFLSTESEQLTWKAEGLPSDELSMENALVILQSSQRPFLVDPSSRATXWLKVHMKNN 362

Query: 3298 HL 3299
             L
Sbjct: 363  RL 368
>37041
          Length = 350

 Score =  104 bits (260), Expect = 7e-22,   Method: Composition-based stats.
 Identities = 43/102 (42%), Positives = 67/102 (65%)
 Frame = -2

Query: 2029 WSDGVLTNSARQVVREPQDVSSWIICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGP 2088
            W+DG+ +   R+  +  +    W++ DG +D  WIE+LNSVLDDN+ LT+ +G+RI   P
Sbjct: 310  WTDGIFSTLWRRTHKTKKGEHVWLVLDGPVDAIWIENLNSVLDDNKTLTLANGDRIPMAP 131

Query: 2089 NVNFVFETHDLSCASPATISRMGMIFLSDEETDLNSLIKSWL 2130
            N   +FE H++  ASPAT+SR GM+F+S    D + +++ WL
Sbjct: 130  NCKIIFEVHNIDNASPATVSRNGMVFMSSSILDWDPILQGWL 5
>14519
          Length = 945

 Score = 86.3 bits (212), Expect = 3e-16,   Method: Compositional matrix adjust.
 Identities = 49/210 (23%), Positives = 94/210 (44%), Gaps = 5/210 (2%)
 Frame = -3

Query: 2624 NLDILLFQEVLEYMSRIDRVLSFPGGSLLLAGRSGVGRRTVTSLVSHMHGAVLFSPKISR 2683
             +D++ F++ + ++ +I R++  P G  LL G  G G++++T L S + G   F   ++R
Sbjct: 691  GMDLVFFKDAMIHLLKISRIIRTPRGHALLVGVGGSGKQSLTRLSSFIAGYKTFQITLTR 512

Query: 2684 GYEPKQFRNDLKHVLQLAGIEAQQVVLLLEDYQFVHPTFLEMINSLLASGEVPGLYTXXX 2743
             Y      +DLK++ + AG E + +  +  D +     FLE +N++L+SG V  L+    
Sbjct: 511  SYNVSNLLDDLKNLYRTAGQEGKGITFIFTDQEIKDEGFLEYLNNMLSSGVVANLFARDE 332

Query: 2744 XXXXXXXXKDQASQDGFFGP-----VFNYFTYRIQQNLHIVLIMDSANLNFIVNCESNPA 2798
                          +    P     ++ Y+  R++ NLH+ L        F       P 
Sbjct: 331  MDEILGELVPVMKXEFPRRPPSNENLYEYYLSRVRNNLHVTLCFSPVGEKFRQRALKFPG 152

Query: 2799 LHKKCQVLWMEGWSDSSMKKIPEMLFSETD 2828
            L   C + W + W   ++  + +   +E D
Sbjct: 151  LISGCTMDWFQRWPKDALIAVADHFLAEFD 62
>27572
          Length = 403

 Score = 83.6 bits (205), Expect = 1e-15,   Method: Compositional matrix adjust.
 Identities = 44/126 (34%), Positives = 66/126 (52%), Gaps = 5/126 (3%)
 Frame = +2

Query: 1364 EQTRFNKVDEDFRSIMMDIRKDSRVTTLTTHAGIRNTLLTILDQLQRCQKSLNEFLEEKR 1423
            +  RF+ +D DF+ ++  + K       T    +   L T+   L  C+K+L E+LE KR
Sbjct: 2    DSKRFDGIDTDFKELVGQVEKTKNCVDATNQPKLYERLETLQHNLALCEKALAEYLETKR 181

Query: 1424 SAFPRFYFIGDDDLLEILGQSTNPSVIQSHLKKLFAGINSVCFDEES-----KHITAMKS 1478
             AFPRFYF+   DLL+IL    NP  +  HL KLF  +  + F+++S     K  T M S
Sbjct: 182  LAFPRFYFVSSSDLLDILSNGNNPVSVARHLTKLFDSMAQLKFEKDSSGNEIKVATGMHS 361

Query: 1479 LEGEVV 1484
             +G + 
Sbjct: 362  KDGRIC 379
>28569
          Length = 475

 Score = 71.2 bits (173), Expect = 8e-12,   Method: Compositional matrix adjust.
 Identities = 38/157 (24%), Positives = 79/157 (50%), Gaps = 6/157 (3%)
 Frame = -3

Query: 3131 DLLNSVGQKVSELKEKFQSRTSEAAKLEAEVSKAQETIKAAEVLISQLDREHRRWNAQVA 3190
            +L+  + Q + + KE++    S+A  ++A+++  +  ++ +  L++ L  E +RW A   
Sbjct: 473  NLIQGLEQSIGKYKEEYAVLISQAQAIKADLAAVEAKVERSVALLNSLGNEKQRWEAGSE 294

Query: 3191 EIAEELATLPKRAQLAAAFITYLSAAPEGLRKNCLEEWTKAAGLEKFDLR------RFLC 3244
               +++AT+     L+AAF+ Y     + +R+N    W     L     R       +L 
Sbjct: 293  TFKQQMATIIGDVLLSAAFMAYAGYFDQQMRQNLFGNWCNHLQLAMIQFRPDLARTEYLS 114

Query: 3245 TESEQLIWKSEGLPSDDLSIENALVILQSRVCPFLID 3281
               E+L W++  LP+D+L  ENA+++ +    P ++D
Sbjct: 113  NADERLNWQANALPTDELCTENAIMLKRFNRYPLIVD 3
>12392
          Length = 445

 Score = 65.9 bits (159), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 46/149 (30%), Positives = 71/149 (47%), Gaps = 11/149 (7%)
 Frame = +3

Query: 1534 FPSQILCLAEQIKFTEDVENAIKDHSLHQIEAQLVAKLERYTS----------VDTSSED 1583
            FPSQI  L  Q+ +T D E A+ +       A++  K+   T+          +D ++ D
Sbjct: 30   FPSQIGLLGLQMIWTRDSEEALNN-------ARVDKKIMTNTNQKFLDLLNMLIDQTTRD 188

Query: 1584 PGNSESGILELKLKALILDIIHNIDIVKQLNQVQVHTTDDWAWKKQVRFYMKSD-HTCYV 1642
                E      K + LI   +H  DI   L ++ + + +D+ W KQ RFY K D   C +
Sbjct: 189  LTKIERT----KFETLITIHVHQKDIFDDLVRMHIKSVNDFEWLKQSRFYYKEDTDQCVI 356

Query: 1643 QMVDSELQYTYEYQGNAPKLVYTPLTDKC 1671
             + D +  Y  E+ G   +LV TPLTD+C
Sbjct: 357  SITDVDFLYMNEFLGCTDRLVITPLTDRC 443
>20622
          Length = 448

 Score = 65.5 bits (158), Expect = 5e-10,   Method: Composition-based stats.
 Identities = 44/155 (28%), Positives = 62/155 (40%), Gaps = 3/155 (1%)
 Frame = -2

Query: 3839 LMRTYESWTPEQISKRDNIHRAHALFSLAWFHAACQERRNYIPQGWTKFYEFSLSDLRAG 3898
            L RTY   T + +   +       L+ + + H   QERR + P GW   YEF+ SD  A 
Sbjct: 447  LKRTYAGITQDYLDISNMPQWKPMLYGVGFLHTIVQERRKFGPLGWNIPYEFNTSDYNAS 268

Query: 3899 YHVIDRLFDG---TKDVQWEFVHGLLENSIYGGRVDNYFDLRVLQSYLKQFFNSSIIDVL 3955
               +    D     K V W  V  +     YGGRV + FD R+L ++ + +F        
Sbjct: 267  VQFVQNHLDDMDIKKGVNWICVRYMFGEIQYGGRVTDDFDKRLLNTFCRVWFGE------ 106

Query: 3956 NQRNKKSIFPYSISLPNSCSILDYRAVIEKLPEDD 3990
            N       F     +P    I +Y   I  LP  D
Sbjct: 105  NMFTPAFNFYKGYVIPKCAKINEYHEYINSLPSSD 1
>20268
          Length = 416

 Score = 57.8 bits (138), Expect = 1e-07,   Method: Composition-based stats.
 Identities = 26/70 (37%), Positives = 45/70 (64%)
 Frame = -1

Query: 1404 ILDQLQRCQKSLNEFLEEKRSAFPRFYFIGDDDLLEILGQSTNPSVIQSHLKKLFAGINS 1463
            I ++L+ C KSL  +L+ KR AFPRFYF+ D+ LL +L +  +   ++ HL+ +F  ++ 
Sbjct: 269  IHEELEICFKSLMGYLDNKRRAFPRFYFVSDNILLALLSRPNDLDSVRPHLRSIFMQLHD 90

Query: 1464 VCFDEESKHI 1473
            V  ++  +HI
Sbjct: 89   VKLEKAHEHI 60
>32781
          Length = 632

 Score = 56.6 bits (135), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 36/124 (29%), Positives = 54/124 (43%), Gaps = 9/124 (7%)
 Frame = -3

Query: 3178 LDREHRRWNAQVAEIAEELATLPKRAQLAAAFITYLSAAPEGLRKNCLEEWTKA--AGL- 3234
            L  E+ RW   + +      TLP    +  AF++Y+ +     R    E        GL 
Sbjct: 498  LASENVRWADSIQQFRINEQTLPGDVLMITAFVSYVGSFTXRYRTELFETHLTPFLKGLK 319

Query: 3235 ------EKFDLRRFLCTESEQLIWKSEGLPSDDLSIENALVILQSRVCPFLIDPSSQATE 3288
                  E  D    L  +++   W +EGLPSD +S ENA ++      P +IDP  Q  +
Sbjct: 318  YPVPVSEGLDPLTMLVDDADIAGWNNEGLPSDRMSTENATILTSCERWPLMIDPQLQGIK 139

Query: 3289 WLKT 3292
            W+KT
Sbjct: 138  WIKT 127
>35960
          Length = 734

 Score = 54.3 bits (129), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 41/124 (33%), Positives = 63/124 (50%), Gaps = 4/124 (3%)
 Frame = +1

Query: 3674 VLVVQALRPDRLQSAMALFACKALG--LKELSPLPLNLKRLYK-ETXXXXXXXXXXXXGA 3730
            +LV+QALRPDRL +   +F  K LG     ++   LNL  + + E             G 
Sbjct: 367  LLVIQALRPDRLIAMARIFVEKTLGSDFVHITEKELNLSLIVETEIKGSTPVLMCSAPGY 546

Query: 3731 DPSQELQELASAERSSECYHQVAMGQGQA-DLAIQMLKECARNGDWLCLKNLHLVVSWLP 3789
            DPS  + +LA AE S +    +A+G  +    A + +   +++G W+ LKN+HL   WL 
Sbjct: 547  DPSSRVDDLA-AELSKQMT-SIAIGSAEGFSQAEKAINSSSKSGRWVLLKNVHLAPQWLV 720

Query: 3790 VLEK 3793
             LE+
Sbjct: 721  QLER 732
>36750
          Length = 1066

 Score = 41.2 bits (95), Expect = 0.010,   Method: Compositional matrix adjust.
 Identities = 44/213 (20%), Positives = 89/213 (41%), Gaps = 13/213 (6%)
 Frame = -1

Query: 2343 GRVYRPKDCERLVLYLKDINLPKLDKWGTSTLVAFLQQVLTYQGFY--DENLEWVGLENI 2400
            G+   P   +++ ++L DIN+P +++WG       ++Q++   GFY  ++  ++  + ++
Sbjct: 820  GQHVWPSSWQKMTVFLDDINMPIINEWGDQVANEIVRQLMENGGFYSLEKPGDFTTIADV 641

Query: 2401 QIVASMSAGGRLGRHKLTTRFTSIVRLCAIDYPEREQLQTIYGAYLEAVLHKNLKNHSIW 2460
            Q +A+M   G  GR+ +  R      +     P    +  I+    +    K        
Sbjct: 640  QFLAAMIQPGG-GRNDIPQRLKRQFVIFNCTLPSNTSIDKIFSVIGQGHFCKER------ 482

Query: 2461 GSSSKIYLLAGSMVQVYEQV-----------RAKFTVDEYSHYFFTPCILTQWVLGLFRY 2509
            G S+K+  +   +V V  ++            AKF      HY F    L++   G+ + 
Sbjct: 481  GFSNKVIEMVKRIVPVTRRLWQLTKIKMLPTPAKF------HYIFNLRDLSRIWQGMLKT 320

Query: 2510 DLEGGSSNHPLDYVLEIVAYEARRLFRDKIVGV 2542
                 +S   L Y+ +   +E  R+  D+ V V
Sbjct: 319  SSSTVNSEKVLMYLWK---HECCRVIADRCVTV 230
>19780
          Length = 1009

 Score = 37.4 bits (85), Expect = 0.12,   Method: Compositional matrix adjust.
 Identities = 25/106 (23%), Positives = 50/106 (47%), Gaps = 6/106 (5%)
 Frame = +1

Query: 2290 VGPEGCGKGMLLRYAFSQLRSTEIAT--IHCSAQTTSRHLLQKLSQTCMVISTNTGR--- 2344
            VGP G GK M +    ++  + E     I  SA+T++       +QT  +I     +   
Sbjct: 433  VGPTGTGKTMTISDKLTRNMAKEYIPDFIVFSAKTSA-------NQTQDLIDGKLDKRRK 591

Query: 2345 -VYRPKDCERLVLYLKDINLPKLDKWGTSTLVAFLQQVLTYQGFYD 2389
             V+ P   +  + ++ D+N+P  + +G    +  ++Q + + G+YD
Sbjct: 592  GVFGPPLGKYFIFFIDDLNMPAREVYGAQPPIELIRQWMDFNGWYD 729
>00365
          Length = 1068

 Score = 35.4 bits (80), Expect = 0.52,   Method: Composition-based stats.
 Identities = 16/40 (40%), Positives = 22/40 (55%)
 Frame = +1

Query: 2345 VYRPKDCERLVLYLKDINLPKLDKWGTSTLVAFLQQVLTY 2384
            +Y+P  CERLVL++  I  PK  K      V F QQ+  +
Sbjct: 658  LYKPSSCERLVLHITSICHPKSVKLYXFDFVLFFQQITIF 777
>39834
          Length = 291

 Score = 33.1 bits (74), Expect = 2.2,   Method: Composition-based stats.
 Identities = 17/51 (33%), Positives = 29/51 (56%)
 Frame = +2

Query: 1121 SKDIESCAQIWALYEEFQQGLQDMAKEDWITYRAKIYLFEEFLINWHERLR 1171
            S+D+E C  +W  + E+  GL   A   W   R+++Y+  +++  W ERLR
Sbjct: 11   SRDVEVCELLWVFW-EWX*GLCGFASVXWNVNRSRLYMDGQYIQYW-ERLR 157
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|9910592|ref|NP_064396.1| ring finger protein 14 [Mus
musculus]
         (485 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

17834                                                                 164   5e-41
20921                                                                 140   1e-33
13884                                                                  74   1e-13
27169                                                                  66   4e-11
13330                                                                  64   2e-10
09209                                                                  32   0.47 
21917                                                                  29   4.3  
>17834
          Length = 732

 Score =  164 bits (416), Expect = 5e-41,   Method: Compositional matrix adjust.
 Identities = 78/145 (53%), Positives = 98/145 (67%)
 Frame = +1

Query: 318 PVMQEPGGTMAICSSCNFAFCTLCRLTYHGLSPCKVTAEKLIDLRNEYLQADEATKRFLE 377
           PV++E    M  C+ C   FC LC  +YHG +PC++ AE+L  LR +YL+ ++ TK FLE
Sbjct: 4   PVIKED--NMGRCARCRHVFCVLCTNSYHGPTPCRIKAEELRKLREKYLRGNKETKEFLE 177

Query: 378 QRYGKRVIQKALEEMESKDWLEKNSKSCPCCGTPIQKLDGCNKMTCTGCMQYFCWICMGS 437
           +RYGKR IQ+ALEE  S +WLEKN+K CP CGT IQK DGCNKMTC+ C  +FCW+C   
Sbjct: 178 KRYGKRAIQQALEETFSAEWLEKNAKMCPSCGTQIQKTDGCNKMTCSKCRSHFCWLCNAF 357

Query: 438 LSRANPYRHFTDSESPCFNRLFHAV 462
           L   NPY HF  S   CF +LF  V
Sbjct: 358 L-HGNPYDHFNRSGGNCFQKLFEGV 429

 Score = 31.6 bits (70), Expect = 0.73,   Method: Compositional matrix adjust.
 Identities = 29/115 (25%), Positives = 44/115 (38%), Gaps = 6/115 (5%)
 Frame = +1

Query: 239 CKHVYCKACLKDYF---EIQIKDGQVKCLNCPEPQCPSVATPGQVKELVEADLFARYDRL 295
           C+HV+C  C   Y      +IK  +++ L     +   +    + KE +E     R  + 
Sbjct: 43  CRHVFCVLCTNSYHGPTPCRIKAEELRKL-----REKYLRGNKETKEFLEKRYGKRAIQQ 207

Query: 296 LLQSTLD---LMADVVYCPRPCCQLPVMQEPGGTMAICSSCNFAFCTLCRLTYHG 347
            L+ T     L  +   CP   C   + +  G     CS C   FC LC    HG
Sbjct: 208 ALEETFSAEWLEKNAKMCPS--CGTQIQKTDGCNKMTCSKCRSHFCWLCNAFLHG 366
>20921
          Length = 649

 Score =  140 bits (353), Expect = 1e-33,   Method: Compositional matrix adjust.
 Identities = 66/138 (47%), Positives = 93/138 (67%), Gaps = 1/138 (0%)
 Frame = -1

Query: 182 ETVDERAVQD-VESLSSLIQEILDFNQARQTKCFNSKLFLCSICFCEKLGSDCMYFLECK 240
           + +D RA+Q+ + S S L+  +LDFN+ ++   F   +  C +CF E+ G  C+ F  C 
Sbjct: 415 DGLDCRAMQEGLMSASHLLTRLLDFNRKKEHADFEHSIVQCDVCFTERAGRMCLRFDNCG 236

Query: 241 HVYCKACLKDYFEIQIKDGQVKCLNCPEPQCPSVATPGQVKELVEADLFARYDRLLLQST 300
           H +CK CL+++F +QI DG VK LNCP P+C S A P QVKELV  +L+ RY+ +LLQ+T
Sbjct: 235 HAFCKDCLREFFTVQINDGNVKALNCPTPKCESQAHPNQVKELVSQELYERYESMLLQTT 56

Query: 301 LDLMADVVYCPRPCCQLP 318
           L+ M+DVVYCPR  CQ P
Sbjct: 55  LEAMSDVVYCPRRACQNP 2
>13884
          Length = 1423

 Score = 74.3 bits (181), Expect = 1e-13,   Method: Compositional matrix adjust.
 Identities = 48/193 (24%), Positives = 80/193 (41%), Gaps = 3/193 (1%)
 Frame = -2

Query: 247  CLKDYFEIQIKDGQVKCLNCPEPQCPSVATPGQV--KELVEADLFARYDRLLLQSTLDLM 304
            C   +F  QI+ G    + C   +C  V  P       L ++ L  R+ +L     +   
Sbjct: 1416 CWDMHFRFQIEQGVTMGIECMGQKC-KVLVPEDFLHTALTDSKLRDRFSKLCFMDLIKGH 1240

Query: 305  ADVVYCPRPCCQLPV-MQEPGGTMAICSSCNFAFCTLCRLTYHGLSPCKVTAEKLIDLRN 363
              + +CP P C + +  +EP      CS C  ++C  C + YH  + C V          
Sbjct: 1239 PKLRFCPGPNCSVIIHAKEPRAKKVECSLCKSSYCFRCGIEYHAPTDCDVI--------- 1087

Query: 364  EYLQADEATKRFLEQRYGKRVIQKALEEMESKDWLEKNSKSCPCCGTPIQKLDGCNKMTC 423
                              K+ + K  ++ E+ +++  ++K CP C   I+K  GCN M C
Sbjct: 1086 ------------------KKWLTKCADDSETANYISAHTKDCPSCHVCIEKSAGCNHMQC 961

Query: 424  TGCMQYFCWICMG 436
            + C   FCW+C+G
Sbjct: 960  SKCKFDFCWMCLG 922
>27169
          Length = 1747

 Score = 65.9 bits (159), Expect = 4e-11,   Method: Compositional matrix adjust.
 Identities = 59/226 (26%), Positives = 92/226 (40%), Gaps = 4/226 (1%)
 Frame = -2

Query: 215  NSKLFLCSICFCEKLGSDCMYFLECKHVYCKACLKDYFEIQIKDGQVKCLNCP----EPQ 270
            N++ F C ICF +    + +   EC H +C++CL D   +  +      L CP      +
Sbjct: 1557 NTEPFSCPICFDDINIGEGVVLRECLHQFCRSCLTDTVRLTEEAE----LTCPFQDDHYR 1390

Query: 271  CPSVATPGQVKELVEADLFARYDRLLLQSTLDLMADVVYCPRPCCQLPVMQEPGGTMAIC 330
            C +     +V+ LV   ++ RY R  L       ++  +C  P C    + E       C
Sbjct: 1389 CDARLQEREVRALVSEQVYERYLRRSLDVAESQASNSYHCKTPDCHGWCLYEDLVNFFKC 1210

Query: 331  SSCNFAFCTLCRLTYHGLSPCKVTAEKLIDLRNEYLQADEATKRFLEQRYGKRVIQKALE 390
              C    C  CR  + G+  CK   E L  +R    +A + T             Q  L+
Sbjct: 1209 PVCQHENCLTCRAIHEGMD-CKQYQEDL-KIRAANDKAAQQT-------------QIMLQ 1075

Query: 391  EMESKDWLEKNSKSCPCCGTPIQKLDGCNKMTCTGCMQYFCWICMG 436
            EM  K      + +CP C   +QK DGC+ + C+ C    CW+  G
Sbjct: 1074 EMVEK----GEAMACPQCQVVVQKKDGCDWIRCSICKTEICWVTKG 949
>13330
          Length = 1670

 Score = 63.5 bits (153), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 51/203 (25%), Positives = 80/203 (39%), Gaps = 4/203 (1%)
 Frame = -1

Query: 234  MYFLECKHVYCKACLKDYFEIQI-KDGQVKCLNCPEPQCPSVATPGQVKELV-EADLFAR 291
            M  LEC H +C  C  DY   +I ++G  + ++C    C  +     V  L+ E  +  +
Sbjct: 1625 MTGLECGHQFCCRCWADYLTSKIMEEGMGQTISCAAYGCDILVDDTTVMTLIREPRVKLK 1446

Query: 292  YDRLLLQSTLDLMADVVYCPRPCCQLPVMQEPGGTMAICSSCNFAFCTLCRLTYHGLSPC 351
            Y +L+  S ++    + +CP P C   V         +   C   FC  C   +H    C
Sbjct: 1445 YQQLITNSFVECNRLLRWCPAPDCGHAVKVSYHDAKPVTCVCGHIFCFTCGENWHDPVKC 1266

Query: 352  KVTAEKLIDLRNEYLQADEATKRFLEQRYGKRVIQKALEEMESKDWLEKNSKSCPCCGTP 411
                                       R+ +  I+K  ++ E+ +W+  N+K CP C   
Sbjct: 1265 ---------------------------RWLRFWIKKCDDDSETSNWIAANTKECPKCQVT 1167

Query: 412  IQKLDGCNKMTCTG--CMQYFCW 432
            I+K  GCN M C    C   FCW
Sbjct: 1166 IEKDGGCNHMVCKNQHCKADFCW 1098
>09209
          Length = 1416

 Score = 32.3 bits (72), Expect = 0.47,   Method: Compositional matrix adjust.
 Identities = 30/112 (26%), Positives = 47/112 (41%)
 Frame = +2

Query: 250 DYFEIQIKDGQVKCLNCPEPQCPSVATPGQVKELVEADLFARYDRLLLQSTLDLMADVVY 309
           D  E  IK  Q   +N P+           V++LV A    ++D ++    ++ +ADV  
Sbjct: 203 DASEENIKTAQAHMINDPKVARNITYIQSTVEDLV-ATQAGKFDAVVASEVVEHVADVST 379

Query: 310 CPRPCCQLPVMQEPGGTMAICSSCNFAFCTLCRLTYHGLSPCKVTAEKLIDL 361
               CCQL    +PGG++         F T    TY   +   V AE ++ L
Sbjct: 380 FITACCQL---VKPGGSI---------FLTTLNKTYLSYTLGVVAAENVLRL 499
>21917
          Length = 682

 Score = 28.9 bits (63), Expect = 4.3,   Method: Compositional matrix adjust.
 Identities = 15/47 (31%), Positives = 22/47 (46%)
 Frame = +2

Query: 413 QKLDGCNKMTCTGCMQYFCWICMGSLSRANPYRHFTDSESPCFNRLF 459
           QKL+ C K  C   +  + W+CM  +     Y +F   E  C N +F
Sbjct: 137 QKLNLCIKYVCVCVICIYMWVCMIYI-----YIYFKTYEHVCVNVMF 262
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|13385434|ref|NP_080215.1|
phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole
succinocarboxamide synthetase [Mus musculus]
         (425 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

27937                                                                 164   7e-41
26437                                                                 117   1e-27
36781                                                                  32   0.40 
04173                                                                  30   2.0  
30803                                                                  30   2.4  
>27937
          Length = 378

 Score =  164 bits (415), Expect = 7e-41,   Method: Compositional matrix adjust.
 Identities = 76/121 (62%), Positives = 96/121 (79%)
 Frame = +3

Query: 16  GKTKEVYELLDTPGRVLLQSKDQITAGNAARKNHLEGKAAISNKITSCIFQLLQEAGIKT 75
           G+TK VY + D P +VL+QSKD+ITAG+ AR + LEGKAAIS   T  IF+LL  AGIKT
Sbjct: 15  GETKVVYAITDCPAQVLVQSKDRITAGDGARAHDLEGKAAISTATTCAIFELLNNAGIKT 194

Query: 76  AFTKKCGETAFIAPQCEMIPIEWVCRRIATGSFLKRNPGVQEGYKFYPPKVEMFFKDDAN 135
            + +K  +TAF+A +C MIPIEWV RR+ATGSFL+R+ GV+EG++F PPK+E FFKDDAN
Sbjct: 195 HYIRKQTDTAFVARRCAMIPIEWVTRRVATGSFLRRHSGVKEGFRFCPPKMETFFKDDAN 374

Query: 136 N 136
           N
Sbjct: 375 N 377
>26437
          Length = 436

 Score =  117 bits (293), Expect(2) = 1e-27,   Method: Compositional matrix adjust.
 Identities = 50/73 (68%), Positives = 64/73 (87%)
 Frame = +3

Query: 329 AGRSNGLGPVLSGNTAYPVISCPPITPDWGAQDVWSSLRLPSGIGCSTILSPEGSAQFAA 388
           AGRSNGLGPVLSGN+ +PVI+CPP++ DWGAQDVWSS+RLPSG+GC T++SPE +A  AA
Sbjct: 3   AGRSNGLGPVLSGNSTWPVINCPPLSADWGAQDVWSSMRLPSGLGCGTVMSPEAAALNAA 182

Query: 389 QIFGLNNHLVWAK 401
           QI  L +H++W+K
Sbjct: 183 QILSLTDHVIWSK 221

 Score = 23.9 bits (50), Expect(2) = 1e-27,   Method: Compositional matrix adjust.
 Identities = 10/14 (71%), Positives = 11/14 (78%)
 Frame = +1

Query: 400 AKLRASILNTWISL 413
           AKLRA  LNTW+ L
Sbjct: 217 AKLRARKLNTWVDL 258
>36781
          Length = 429

 Score = 32.3 bits (72), Expect = 0.40,   Method: Compositional matrix adjust.
 Identities = 13/21 (61%), Positives = 16/21 (76%)
 Frame = -2

Query: 88  APQCEMIPIEWVCRRIATGSF 108
           A QCEMI  +++CRRI  GSF
Sbjct: 350 AQQCEMIR*DYLCRRIKYGSF 288
>04173
          Length = 1616

 Score = 30.0 bits (66), Expect = 2.0,   Method: Compositional matrix adjust.
 Identities = 14/31 (45%), Positives = 20/31 (64%), Gaps = 4/31 (12%)
 Frame = +2

Query: 329 AGRSN----GLGPVLSGNTAYPVISCPPITP 355
           AG SN     +GPV++ +T  PV + PP+TP
Sbjct: 902 AGASNMPDSTVGPVVAASTVXPVQTSPPVTP 994
>30803
          Length = 431

 Score = 29.6 bits (65), Expect = 2.4,   Method: Compositional matrix adjust.
 Identities = 19/58 (32%), Positives = 26/58 (44%), Gaps = 2/58 (3%)
 Frame = -2

Query: 48  NHLEGKAAISNKITSCIFQLLQEAG--IKTAFTKKCGETAFIAPQCEMIPIEWVCRRI 103
            H+ G A   ++I     +LLQEAG     +     G+TA     C+M    W C RI
Sbjct: 196 THVFGAAEKKSRIPLLFLELLQEAGEAFMRSMMVSLGDTATSVAICQM*FTYWXCPRI 23
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6679587|ref|NP_033022.1| RAB1, member RAS oncogene
family [Mus musculus]
         (205 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

34468                                                                 162   7e-41
08428                                                                 152   1e-37
33374                                                                 120   6e-35
05468                                                                 112   1e-25
26083                                                                 111   2e-25
14456                                                                 108   1e-24
33380                                                                 104   2e-24
32723                                                                 107   4e-24
33794                                                                 107   4e-24
07465                                                                 106   7e-24
17511                                                                 102   7e-23
13901                                                                  97   4e-21
07580                                                                  96   1e-20
01095                                                                  93   6e-20
30760                                                                  91   3e-19
01398                                                                  89   1e-18
01972                                                                  78   3e-18
19006                                                                  86   1e-17
11257                                                                  85   2e-17
35581                                                                  82   2e-16
00858                                                                  82   2e-16
34597                                                                  76   1e-15
26536                                                                  78   3e-15
12339                                                                  78   3e-15
27191                                                                  77   4e-15
11728                                                                  74   4e-14
13750                                                                  71   2e-13
13745                                                                  71   3e-13
34359                                                                  68   3e-12
19656                                                                  67   4e-12
29380                                                                  62   1e-10
09204                                                                  60   5e-10
19046                                                                  58   2e-09
24619                                                                  57   5e-09
08153                                                                  55   2e-08
14119                                                                  52   1e-07
09827                                                                  52   1e-07
25618                                                                  50   9e-07
00552                                                                  49   2e-06
14775                                                                  47   4e-06
10862                                                                  47   5e-06
33605                                                                  47   5e-06
18509                                                                  47   5e-06
31291                                                                  46   9e-06
25796                                                                  44   5e-05
12443                                                                  40   9e-04
10708                                                                  34   0.039
31928                                                                  33   0.061
06994                                                                  31   0.38 
18184                                                                  30   0.74 
28005                                                                  27   4.8  
>34468
          Length = 1502

 Score =  162 bits (411), Expect = 7e-41,   Method: Compositional matrix adjust.
 Identities = 77/176 (43%), Positives = 120/176 (68%), Gaps = 7/176 (3%)
 Frame = +1

Query: 11  LFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQ 70
           +FK+++IGDS VGK+CL  RF    + +   +TIGVDF+ ++I++D + +KLQ+WDTAGQ
Sbjct: 493 IFKIIVIGDSNVGKTCLTYRFCLGKFPDKTEATIGVDFREKSIQVDSEHLKLQLWDTAGQ 672

Query: 71  ERFR-TITSSYYRGAHGIIVVYDVTDQESFNNVKQWLQEIDRY-ASENVNKLLVGNKCDL 128
           ERFR ++   YYR  H ++ VYD+T   SF N+  W++E DR+  ++ + ++LVGNKCD+
Sbjct: 673 ERFRKSMVQHYYRNVHAVVFVYDMTKMSSFENMPAWIEECDRHNLTKYIPRILVGNKCDV 852

Query: 129 TTKKVVDYTTAKEFADSLGIPFLETSAKN---ATNVEQSFMTMAAEIK--KRMGPG 179
             +  V+   A++FAD+  +P  ETSAK+   A +V+  FMT+A ++K  K M P 
Sbjct: 853 VERIAVNTNLAQKFADAHNMPLFETSAKDDEKANHVDAIFMTVAHKLKXSKPMMPA 1020
>08428
          Length = 1109

 Score =  152 bits (384), Expect = 1e-37,   Method: Compositional matrix adjust.
 Identities = 72/160 (45%), Positives = 101/160 (63%)
 Frame = -3

Query: 13   KLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQER 72
            K+ L+GDSGVGKS ++LRF   +Y  S  STIG  F  +++ +DG   + QIWDTAGQE+
Sbjct: 1065 KVCLLGDSGVGKSSIVLRFVTGSYRPSQESTIGASFMSKSLVVDGAGYRFQIWDTAGQEK 886

Query: 73   FRTITSSYYRGAHGIIVVYDVTDQESFNNVKQWLQEIDRYASENVNKLLVGNKCDLTTKK 132
            FR +   YYRGA   ++VYDVT   +F +VK W+QE+  +   N+   + GNKCDL   +
Sbjct: 885  FRALAPMYYRGAAAAVIVYDVTRPRTFKSVKSWIQELRSFGPPNIVLAIAGNKCDLEELR 706

Query: 133  VVDYTTAKEFADSLGIPFLETSAKNATNVEQSFMTMAAEI 172
             V    A+E+A S+   F ETSA  A NVE+ F  +A ++
Sbjct: 705  EVVEKDAQEYASSISAIFGETSAMTAVNVEEMFTELARQL 586
>33374
          Length = 489

 Score =  120 bits (302), Expect(2) = 6e-35,   Method: Compositional matrix adjust.
 Identities = 54/114 (47%), Positives = 78/114 (68%)
 Frame = +1

Query: 48  FKIRTIELDGKTIKLQIWDTAGQERFRTITSSYYRGAHGIIVVYDVTDQESFNNVKQWLQ 107
           F  +T+ LD  T+K +IWDTAGQER+ ++   YYRGA   IVVYD+T+Q++F   K W++
Sbjct: 139 FLTQTVCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNQDTFGRAKTWVK 318

Query: 108 EIDRYASENVNKLLVGNKCDLTTKKVVDYTTAKEFADSLGIPFLETSAKNATNV 161
           E+ R AS N+   L GNK DL  K++V++  A+ +A+   + F+ETSAK A NV
Sbjct: 319 ELQRQASPNIVIALAGNKADLANKRMVEFEEAQAYAEENSLLFMETSAKTAMNV 480

 Score = 43.5 bits (101), Expect(2) = 6e-35,   Method: Compositional matrix adjust.
 Identities = 22/44 (50%), Positives = 28/44 (63%)
 Frame = +2

Query: 12 FKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIEL 55
          FKL+L+G+S VGKS L+LRF    + E   STIG  F +R   L
Sbjct: 32 FKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAF*LRQFVL 163
>05468
          Length = 1558

 Score =  112 bits (280), Expect = 1e-25,   Method: Compositional matrix adjust.
 Identities = 68/207 (32%), Positives = 114/207 (55%), Gaps = 10/207 (4%)
 Frame = -3

Query: 9    DYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKT-IKLQIWDT 67
            ++L+K+L+IG+ G GK+ ++ R+    +++ Y +TIGVDF ++ +  D  T I+LQ+WD 
Sbjct: 1547 EHLYKILVIGELGTGKTSIIKRYVHQFFSQHYRATIGVDFALKVLNWDADTLIRLQLWDI 1368

Query: 68   AGQERFRTITSSYYRGAHGIIVVYDVTDQESFNNVKQWLQEIDRYAS----ENVNKLLVG 123
            AGQERF  +T  YY+ A G  VV+DVT   +F+ V +W  ++D          V  +L+ 
Sbjct: 1367 AGQERFGNMTRVYYKEAVGAFVVFDVTRASTFDAVTKWKNDLDSKVQLADGSPVPCVLLA 1188

Query: 124  NKCDLTTKKVVDYTT-AKEFADSLG-IPFLETSAKNATNVEQS---FMTMAAEIKKRMGP 178
            NKCD   + +V+ T+   EF    G I + ETSAK   N++++    +T   E  + M  
Sbjct: 1187 NKCDQAKEGLVNNTSQMDEFCSEKGFIGWYETSAKENINIDEAARFLVTRILEKDRAMQL 1008

Query: 179  GATAGGAEKSNVKIQSTPVKQSGGGCC 205
            G      ++  +   S+  ++    CC
Sbjct: 1007 GDDDRDRDRIVLDKPSSGTQERKINCC 927
>26083
          Length = 432

 Score =  111 bits (278), Expect = 2e-25,   Method: Compositional matrix adjust.
 Identities = 50/114 (43%), Positives = 79/114 (69%)
 Frame = +1

Query: 12  FKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQE 71
           FKL+ +G+  VGK+ L+ RF  D++  +Y +TIG+DF  +T+ L+ +TI+LQ+WDTAGQE
Sbjct: 79  FKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTIRLQLWDTAGQE 258

Query: 72  RFRTITSSYYRGAHGIIVVYDVTDQESFNNVKQWLQEIDRYASENVNKLLVGNK 125
           RFR++  SY R +   +VVYD+T+  SF+   +W+ ++      +V  +LVGNK
Sbjct: 259 RFRSLIPSYIRDSSVAVVVYDITNANSFHQTSKWIDDVRTERGSDVIIMLVGNK 420
>14456
          Length = 1867

 Score =  108 bits (271), Expect = 1e-24,   Method: Compositional matrix adjust.
 Identities = 55/158 (34%), Positives = 91/158 (57%), Gaps = 4/158 (2%)
 Frame = -1

Query: 21   GVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRTITSSY 80
            GVGKS L+ RF  + +      TIGV+F  + + +D +T  +QIWDTAGQERF+++ + +
Sbjct: 1111 GVGKSSLMNRFVSNKFDAQSFHTIGVEFLNKDVVVDDETYTMQIWDTAGQERFKSLRTPF 932

Query: 81   YRGAHGIIVVYDVTDQESFNNVKQWLQEIDRYAS----ENVNKLLVGNKCDLTTKKVVDY 136
            YRGA   ++ + V   +SF N+  W +E   YA          +++GNK D+  ++V + 
Sbjct: 931  YRGADCCLLTFSVDSMQSFRNLSMWRKEFLYYADIQDGVTFPFVVLGNKIDVEGRQVTNE 752

Query: 137  TTAKEFADSLGIPFLETSAKNATNVEQSFMTMAAEIKK 174
                    +   P+ ETSAK+ATNVE++F+     +++
Sbjct: 751  EARSWCTANSNAPYFETSAKDATNVEKAFLAAVQRLRE 638
>33380
          Length = 282

 Score =  104 bits (259), Expect(2) = 2e-24,   Method: Compositional matrix adjust.
 Identities = 47/82 (57%), Positives = 63/82 (76%)
 Frame = +3

Query: 52  TIELDGKTIKLQIWDTAGQERFRTITSSYYRGAHGIIVVYDVTDQESFNNVKQWLQEIDR 111
           T+    K +KLQIWDTAGQER+RTIT++YYRGA G I++YDVT++ESFN V+ W  +I  
Sbjct: 36  TVFRQDKRVKLQIWDTAGQERYRTITTAYYRGAMGFILMYDVTNEESFNAVQDWCTQIKT 215

Query: 112 YASENVNKLLVGNKCDLTTKKV 133
           Y+ +N   +LVGNKCDL  ++V
Sbjct: 216 YSWDNAQVVLVGNKCDLEDERV 281

 Score = 24.6 bits (52), Expect(2) = 2e-24,   Method: Compositional matrix adjust.
 Identities = 6/15 (40%), Positives = 14/15 (93%)
 Frame = +2

Query: 40 YISTIGVDFKIRTIE 54
          ++ST+G+DFK+ +++
Sbjct: 2  FVSTVGIDFKVNSLQ 46
>32723
          Length = 384

 Score =  107 bits (266), Expect = 4e-24,   Method: Compositional matrix adjust.
 Identities = 52/103 (50%), Positives = 70/103 (67%)
 Frame = +2

Query: 70  QERFRTITSSYYRGAHGIIVVYDVTDQESFNNVKQWLQEIDRYASENVNKLLVGNKCDLT 129
           QERFR+IT SYYR A+ +I+VYDV  Q+S+ ++ QW+ EI+ YA   V   LVGNK D T
Sbjct: 2   QERFRSITQSYYRSANALILVYDVCSQQSYESLPQWIHEIELYAGTKVLAFLVGNKIDQT 181

Query: 130 TKKVVDYTTAKEFADSLGIPFLETSAKNATNVEQSFMTMAAEI 172
            K+ +     KEFA+   + FLETSAK A NVE+ F T+A ++
Sbjct: 182 DKREIPTHIGKEFAERYEMRFLETSAKEADNVEKLFSTIAYQL 310
>33794
          Length = 779

 Score =  107 bits (266), Expect = 4e-24,   Method: Compositional matrix adjust.
 Identities = 56/132 (42%), Positives = 81/132 (61%)
 Frame = -1

Query: 46  VDFKIRTIELDGKTIKLQIWDTAGQERFRTITSSYYRGAHGIIVVYDVTDQESFNNVKQW 105
           V +K  TI L+GK +KLQIWDT+GQ RF TI  SY RGA GII+VYD+T++ SF+ + +W
Sbjct: 692 VAYKTTTILLEGKRVKLQIWDTSGQGRFCTIIRSYSRGAQGIILVYDITNKWSFDGIDRW 513

Query: 106 LQEIDRYASENVNKLLVGNKCDLTTKKVVDYTTAKEFADSLGIPFLETSAKNATNVEQSF 165
           L+E++ +A   + K+LVGN+  L  K+ V    A+ +A    +   E S     N+ +SF
Sbjct: 512 LKEVEEHA-PGIPKVLVGNRLHLAYKRQVAAKQAETYASRNNMSCFEISPLCDFNIRESF 336

Query: 166 MTMAAEIKKRMG 177
             +A     R G
Sbjct: 335 CELARMALHRNG 300
>07465
          Length = 1103

 Score =  106 bits (264), Expect = 7e-24,   Method: Compositional matrix adjust.
 Identities = 54/155 (34%), Positives = 87/155 (56%)
 Frame = +3

Query: 25  SCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRTITSSYYRGA 84
           S ++ R+    +T+ Y  TIGVDF  R IE+ G+ ++L +WDTAGQE F  IT +YYRGA
Sbjct: 240 SSMIQRYCKGIFTKDYKKTIGVDFLERQIEVGGEDVRLMLWDTAGQEEFDAITKAYYRGA 419

Query: 85  HGIIVVYDVTDQESFNNVKQWLQEIDRYASENVNKLLVGNKCDLTTKKVVDYTTAKEFAD 144
              ++ +   D++SF  ++ W ++++    E +  ++V NK DL    VV    A+  A 
Sbjct: 420 QACVLAFSTVDRDSFEALETWKRKVEDEVGE-IGMVIVQNKIDLIDDAVVRPEEAENLAK 596

Query: 145 SLGIPFLETSAKNATNVEQSFMTMAAEIKKRMGPG 179
            L + F  TS K   NV++ F  +A +   ++  G
Sbjct: 597 KLRLRFYRTSVKENMNVDEVFRYLADKYLHQLNTG 701
>17511
          Length = 483

 Score =  102 bits (255), Expect = 7e-23,   Method: Compositional matrix adjust.
 Identities = 48/122 (39%), Positives = 80/122 (65%), Gaps = 4/122 (3%)
 Frame = -3

Query: 11  LFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQ 70
           L K++++GDSGVGK+ L+ ++ +  ++  Y +TIG DF  + + +D + + +QIWDTAGQ
Sbjct: 367 LLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQIWDTAGQ 188

Query: 71  ERFRTITSSYYRGAHGIIVVYDVTDQESFNNVKQWLQEIDRYAS----ENVNKLLVGNKC 126
           ERF+++  ++YRGA   ++V+DVT   +F ++  W  E    AS    EN   +++GNK 
Sbjct: 187 ERFQSLGVAFYRGADCCVLVFDVTMPNTFRSLDSWRDEFLIQASPRDPENFPFVVIGNKI 8

Query: 127 DL 128
           DL
Sbjct: 7   DL 2
>13901
          Length = 962

 Score = 97.1 bits (240), Expect = 4e-21,   Method: Compositional matrix adjust.
 Identities = 43/96 (44%), Positives = 65/96 (67%), Gaps = 1/96 (1%)
 Frame = -3

Query: 11  LFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGK-TIKLQIWDTAG 69
           LFK+++IGD  VGK+  + R+ +D++   Y  TIGVDF ++ I    K  IKLQ+WD AG
Sbjct: 288 LFKVIIIGDPTVGKTSFVQRYVNDSFRRDYKMTIGVDFALKVIRWSDKCNIKLQLWDIAG 109

Query: 70  QERFRTITSSYYRGAHGIIVVYDVTDQESFNNVKQW 105
           QERF ++T  YY+ AH  IV++D+T + ++ N  +W
Sbjct: 108 QERFTSMTRVYYKDAHACIVMFDLTQKNTYQNAIRW 1
>07580
          Length = 921

 Score = 95.5 bits (236), Expect = 1e-20,   Method: Compositional matrix adjust.
 Identities = 51/141 (36%), Positives = 82/141 (58%), Gaps = 1/141 (0%)
 Frame = +3

Query: 36  YTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRTITSSYYRGAHGIIVVYDVTD 95
           + E Y  TI   ++ + +E+DG+   L+I DTAG E+F  +   Y +   G ++ Y +T 
Sbjct: 135 FVEKYDPTIEDSYR-KQVEVDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFLLAYSITA 311

Query: 96  QESFNNVKQWLQEIDRYA-SENVNKLLVGNKCDLTTKKVVDYTTAKEFADSLGIPFLETS 154
           Q +FN++++  ++I R   +++V  LLVGNKCDL  ++VV     +  A S    FLETS
Sbjct: 312 QSTFNDLQELREQILRVKDTDDVPMLLVGNKCDLEDERVVGKDQGQGLARSFSCAFLETS 491

Query: 155 AKNATNVEQSFMTMAAEIKKR 175
           AK   NV + FM +  +I K+
Sbjct: 492 AKARINVNEIFMDLVRQINKK 554
>01095
          Length = 1745

 Score = 93.2 bits (230), Expect = 6e-20,   Method: Compositional matrix adjust.
 Identities = 45/117 (38%), Positives = 72/117 (61%)
 Frame = -1

Query: 89   VVYDVTDQESFNNVKQWLQEIDRYASENVNKLLVGNKCDLTTKKVVDYTTAKEFADSLGI 148
            VVYD+T+Q++F   K W++E+ R AS N+   L GNK DL  K++V++  A+ +A+   +
Sbjct: 1745 VVYDITNQDTFGRAKTWVKELQRQASPNIVIALAGNKADLANKRMVEFEEAQAYAEENSL 1566

Query: 149  PFLETSAKNATNVEQSFMTMAAEIKKRMGPGATAGGAEKSNVKIQSTPVKQSGGGCC 205
             F+ETSAK A NV   F+ +A ++ K  G G +     +  V++ +   +QS GGCC
Sbjct: 1565 LFMETSAKTAMNVNDIFLAIAKKLPKNEGGGGSQ--PRQQGVRLNNEQSQQSEGGCC 1401
>30760
          Length = 596

 Score = 91.3 bits (225), Expect = 3e-19,   Method: Compositional matrix adjust.
 Identities = 54/168 (32%), Positives = 91/168 (54%), Gaps = 6/168 (3%)
 Frame = -1

Query: 13  KLLLIGDSGVGKSCLLLRFADDT--YTESYISTIGVDFKIRTIELDGK--TIKLQIWDTA 68
           K ++ GDSGVGKS +   F  D+  + ++Y  T GV+  ++ + +      ++L ++D+A
Sbjct: 524 KCIVTGDSGVGKSSICQVFHSDSAHFPKNYSMTTGVEVLVKLVNIPDSRDQVELYLFDSA 345

Query: 69  GQERFRTITSSYYRGAHGIIVVYDVTDQESFNNVKQWLQEIDRYASEN--VNKLLVGNKC 126
           G+E F    + ++     ++VVYDVTD+ SF+   +WL+ + R A  N  +  +LV NK 
Sbjct: 344 GKEIFSENVTKFWDQPSVVMVVYDVTDETSFSGCVRWLERV-RAAKPNTVIPGVLVANKT 168

Query: 127 DLTTKKVVDYTTAKEFADSLGIPFLETSAKNATNVEQSFMTMAAEIKK 174
           DL  ++ V     K+ A S G+ + E SAK   N +  F  +A    K
Sbjct: 167 DLDERRRVSRKEGKDLAQSHGLEYFECSAKEMQNTDTPFFCLAHAFHK 24
>01398
          Length = 1421

 Score = 88.6 bits (218), Expect = 1e-18,   Method: Compositional matrix adjust.
 Identities = 50/145 (34%), Positives = 76/145 (52%), Gaps = 9/145 (6%)
 Frame = -2

Query: 70   QERFRTITSSYYRGAHGIIVVYDVTDQESFNNVKQWLQEIDRYASENVNKLLV-GNKCDL 128
            QERFR+IT SYYR + G+I+VYD+T + +F N+KQW +E   +   +    LV G+K D 
Sbjct: 1420 QERFRSITRSYYRNSVGVIIVYDITKRSTFENLKQWYEEARNHIEPHKAIFLVLGHKSDR 1241

Query: 129  TTKKVVDYTTAKEFADSLGIPFLETSAKNATNVEQSFMTMAAEIKKRMGPGATA-----G 183
               + V     + FA+  G+ F ETSAK+  N+E  F  +A +  + +  G         
Sbjct: 1240 EDARQVTAREGRRFAEMHGLKFFETSAKSGHNIEDVFAQIAKDTYQHLQDGHIRLEEGWD 1061

Query: 184  GAEKSNVKIQSTPVKQSG---GGCC 205
            G ++   + + T     G   GGCC
Sbjct: 1060 GVKQGFARPRETVHLAEGEESGGCC 986
>01972
          Length = 2359

 Score = 77.8 bits (190), Expect(2) = 3e-18,   Method: Compositional matrix adjust.
 Identities = 40/135 (29%), Positives = 72/135 (53%)
 Frame = +3

Query: 38  ESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRTITSSYYRGAHGIIVVYDVTDQE 97
           + Y++T+GV+            +K  +WDTAGQE+F  +   YY      ++++DVT + 
Sbjct: 381 KKYVATLGVEVHPLLFHTSRGKLKFNVWDTAGQEKFGGLRDGYYIQGQCAVIMFDVTSRV 560

Query: 98  SFNNVKQWLQEIDRYASENVNKLLVGNKCDLTTKKVVDYTTAKEFADSLGIPFLETSAKN 157
           ++ NV  W +++ R   EN+  +L GNK D+  +KV     A  F     + + + SAK+
Sbjct: 561 TYKNVPNWHRDLVR-VCENIPIVLCGNKVDIKDRKV--KAKAIVFHRKKNLQYYDISAKS 731

Query: 158 ATNVEQSFMTMAAEI 172
             N E+ F+ +A ++
Sbjct: 732 NYNFEKPFLWLARKL 776

 Score = 30.4 bits (67), Expect(2) = 3e-18,   Method: Compositional matrix adjust.
 Identities = 12/36 (33%), Positives = 21/36 (58%)
 Frame = +1

Query: 7   EYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYIS 42
           E +  FKL+L+GD GVGK+  + R     + ++ + 
Sbjct: 289 EQEPTFKLVLVGDGGVGKTTFVKRHVTGEFEKNMLP 396
>19006
          Length = 568

 Score = 85.5 bits (210), Expect = 1e-17,   Method: Compositional matrix adjust.
 Identities = 45/131 (34%), Positives = 75/131 (57%), Gaps = 1/131 (0%)
 Frame = -2

Query: 13  KLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQER 72
           KL+++GD   GK+CLL+ F+ D + E Y+ T+  ++ +  IE+D K ++L +WDTAGQE 
Sbjct: 432 KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENY-VADIEVDSKQVELALWDTAGQED 256

Query: 73  FRTITSSYYRGAHGIIVVYDVTDQESFNNV-KQWLQEIDRYASENVNKLLVGNKCDLTTK 131
           +  +    Y     I++ + +   +S  N+ ++W  E+ R+   NV  +LVGNK DL   
Sbjct: 255 YDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEV-RHFCPNVPIILVGNKKDLRN- 82

Query: 132 KVVDYTTAKEF 142
              D  T +E 
Sbjct: 81  ---DENTKREL 58
>11257
          Length = 1102

 Score = 85.1 bits (209), Expect = 2e-17,   Method: Compositional matrix adjust.
 Identities = 48/164 (29%), Positives = 87/164 (53%), Gaps = 9/164 (5%)
 Frame = -2

Query: 51   RTIELDGKTIKLQIWDTAGQERFRTITSSYYRGAHGIIVVYDVTDQESFNNVKQWLQEID 110
            + + +DG+T  +QIWDTAGQER++++ + +YRG    ++ + V + +S  ++  W  E  
Sbjct: 1053 KDVVVDGETFTMQIWDTAGQERYKSLRTPFYRGTDCCLLTFSVDNLKSLQSLSDWYDEFV 874

Query: 111  RYA----SENVNKLLVGNKCDLTTKKVVDYTTAKEFADSLGIPFLETSAKNATNVEQSFM 166
             YA    S +   +++GNK D+  ++V              +P+ ETSAK++ NV+Q+F+
Sbjct: 873  NYADIQDSASFPFVIIGNKADIEEREVSSEDAYNWCRTHGNLPYFETSAKDSLNVQQAFL 694

Query: 167  TMA---AEIKKRMG--PGATAGGAEKSNVKIQSTPVKQSGGGCC 205
             +     E+ ++M   P  T     K   K++S+     G G C
Sbjct: 693  AVVRRLREMDEQMDERPTRTDTVDLKRVAKVKSSCC*WGGSGLC 562
>35581
          Length = 364

 Score = 81.6 bits (200), Expect = 2e-16,   Method: Compositional matrix adjust.
 Identities = 37/82 (45%), Positives = 57/82 (69%), Gaps = 1/82 (1%)
 Frame = +2

Query: 12  FKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIEL-DGKTIKLQIWDTAGQ 70
           FK +L+GD+GVGK+CLL R A D + +S ++++     + T+ L  G    + +WDTAGQ
Sbjct: 47  FKCVLLGDAGVGKTCLLNRLATDKFLDSPLTSLTTASLLTTVTLTSGVMASVDLWDTAGQ 226

Query: 71  ERFRTITSSYYRGAHGIIVVYD 92
           ER+R++TSSYYR    +++VYD
Sbjct: 227 ERYRSLTSSYYRDTKAVLIVYD 292
>00858
          Length = 1658

 Score = 81.6 bits (200), Expect = 2e-16,   Method: Compositional matrix adjust.
 Identities = 56/162 (34%), Positives = 89/162 (54%), Gaps = 1/162 (0%)
 Frame = -2

Query: 12   FKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQE 71
            +KL+++G  GVGKS L ++   + + E Y  T   D   + + +DG+T  L I DTAGQE
Sbjct: 1588 YKLVVVGAGGVGKSALTIQLXQNHFVEEYDPTXE-DSXRKQVVIDGETCLLDILDTAGQE 1412

Query: 72   RFRTITSSYYRGAHGIIVVYDVTDQESFNNVKQWLQEIDRYA-SENVNKLLVGNKCDLTT 130
                +     R   G + V+ V + +SF ++ Q+ ++I R   ++ V  +LVGNK DL  
Sbjct: 1411 EXSAMRDQCMRTGEGFLCVFAVXNLKSFEDINQYREQIKRVKDADEVPMVLVGNKVDLPI 1232

Query: 131  KKVVDYTTAKEFADSLGIPFLETSAKNATNVEQSFMTMAAEI 172
            +  V+    K  A+   IP++ETSAK    V+ +F T+  EI
Sbjct: 1231 RN-VEQRQGKHMAELYHIPYVETSAKTRQGVDDAFYTLVREI 1109
>34597
          Length = 773

 Score = 75.9 bits (185), Expect(2) = 1e-15,   Method: Compositional matrix adjust.
 Identities = 35/92 (38%), Positives = 58/92 (63%)
 Frame = -2

Query: 96  QESFNNVKQWLQEIDRYASENVNKLLVGNKCDLTTKKVVDYTTAKEFADSLGIPFLETSA 155
           ++SF N+ +WL+ ID +A+E+V K+++GNKCD+T K+VV     +  A    I F+ETSA
Sbjct: 715 KKSFENIVKWLRNIDEHANEDVEKMILGNKCDMTDKRVVSKERGEAIAREHSIRFMETSA 536

Query: 156 KNATNVEQSFMTMAAEIKKRMGPGATAGGAEK 187
           K+  N+E++F  +A  I  +     +A   E+
Sbjct: 535 KSNINIERAFCELAEAILDKTAGRESAENPER 440

 Score = 23.5 bits (49), Expect(2) = 1e-15,   Method: Compositional matrix adjust.
 Identities = 9/13 (69%), Positives = 12/13 (92%)
 Frame = -3

Query: 78  SSYYRGAHGIIVV 90
           +SYYRGA GI++V
Sbjct: 771 TSYYRGAMGIMLV 733
>26536
          Length = 829

 Score = 77.8 bits (190), Expect = 3e-15,   Method: Compositional matrix adjust.
 Identities = 49/144 (34%), Positives = 74/144 (51%), Gaps = 6/144 (4%)
 Frame = +2

Query: 58  KTIKLQIWDTAGQERFRTITSSYYRGAHGIIVVYDVTDQESFNNVKQWLQEIDRYASE-N 116
           + +     DTAGQE + ++   Y R   G IVVY VTD  SF   +   + + R+  E +
Sbjct: 122 RRVSWTFLDTAGQEEYSSMREHYTRSGDGFIVVYSVTDVTSFQEAEAVFRWLTRFQDETS 301

Query: 117 VNKLLVGNKCDLTTKKVVDYTTAKEFADSLGIPFLETSAKNATNVEQSFMTMAAEIKKRM 176
           ++ +L GNK DLT+ + V     ++ AD LG+ + ETSAK   NV Q +  +   I  R 
Sbjct: 302 IHAVLCGNKTDLTSDRKVTPEEGRKMADRLGMLYFETSAKTGDNVSQVYHGLLRSI-PRS 478

Query: 177 GPGAT-----AGGAEKSNVKIQST 195
           G         +GG  KS++ I+ T
Sbjct: 479 GTDYKIVMLGSGGVGKSSLTIRFT 550

 Score = 37.4 bits (85), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 17/47 (36%), Positives = 31/47 (65%)
 Frame = +2

Query: 12  FKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGK 58
           +K++++G  GVGKS L +RF  DT+ + Y  TI   ++ + I++ G+
Sbjct: 488 YKIVMLGSGGVGKSSLTIRFTQDTFLDVYDPTIEDSYR-KMIQVSGQ 625
>12339
          Length = 578

 Score = 77.8 bits (190), Expect = 3e-15,   Method: Compositional matrix adjust.
 Identities = 42/104 (40%), Positives = 64/104 (61%), Gaps = 4/104 (3%)
 Frame = -2

Query: 70  QERFRTITSSYYRGAHGIIVVYDVTDQESFNNVKQWLQEIDRYAS----ENVNKLLVGNK 125
           QERF+++  ++YRGA   I+VYDVT+ ++F+++  W +E    AS    E+   +++GNK
Sbjct: 577 QERFQSLGVAFYRGADCCILVYDVTEXKTFDSLDSWQREFLNQASPRDPEHFPFVVIGNK 398

Query: 126 CDLTTKKVVDYTTAKEFADSLGIPFLETSAKNATNVEQSFMTMA 169
            DL  + V         +   GIP+ ETSAK A NVEQ+F T+A
Sbjct: 397 IDLDNRVVTAKRGQGWCSTKGGIPYFETSAKEAINVEQAFQTVA 266
>27191
          Length = 443

 Score = 77.4 bits (189), Expect = 4e-15,   Method: Compositional matrix adjust.
 Identities = 30/102 (29%), Positives = 62/102 (60%)
 Frame = +1

Query: 24  KSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRTITSSYYRG 83
           K+CL+  F +  + + Y  T+GVD+  +   ++G  +++ +WD +G   +  + +  Y G
Sbjct: 1   KTCLIKHFCESKFNQGYQPTVGVDYGFKIQTVNGVDMRVHMWDLSGSNEYLDVRNELYTG 180

Query: 84  AHGIIVVYDVTDQESFNNVKQWLQEIDRYASENVNKLLVGNK 125
           +  I +V+DV++  SF  +  WL+EI+R+A+ +   ++VGN+
Sbjct: 181 SDAIFIVFDVSNTPSFEALDSWLREINRFATGSPLNVIVGNR 306
>11728
          Length = 635

 Score = 73.9 bits (180), Expect = 4e-14,   Method: Compositional matrix adjust.
 Identities = 39/122 (31%), Positives = 63/122 (51%), Gaps = 1/122 (0%)
 Frame = -1

Query: 12  FKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQE 71
            K +++GD  VGK+CLL+ +  + +   YI T+  ++    + +D K I L +WDTAGQE
Sbjct: 488 IKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVM-VDSKPINLGLWDTAGQE 312

Query: 72  RFRTITSSYYRGAHGIIVVYDVTDQESFNNVK-QWLQEIDRYASENVNKLLVGNKCDLTT 130
            +  +    Y      ++ + +    SF NVK +W  E+  +   N   +LVG K DL  
Sbjct: 311 DYDRLRPLSYPQTDVFLICFSLISPASFENVKAKWYPEVSHHCP-NTPIILVGTKLDLRE 135

Query: 131 KK 132
            K
Sbjct: 134 DK 129
>13750
          Length = 503

 Score = 71.2 bits (173), Expect = 2e-13,   Method: Compositional matrix adjust.
 Identities = 48/151 (31%), Positives = 77/151 (50%), Gaps = 5/151 (3%)
 Frame = -2

Query: 24  KSCLLLRFADDTYTESYISTIGV---DF-KIRTIELDGKTIKLQIWDTAGQERFRTITSS 79
           K+CLL R+    + +  + TI V   +F + RT   D   ++  +WDT G E +R++  S
Sbjct: 502 KTCLLRRYQKGFFMDRTMPTIAVLCSEFNESRT---DPLNVRYTLWDTGGAETYRSLWVS 332

Query: 80  YYRGAHGIIVVYDVTDQESF-NNVKQWLQEIDRYASENVNKLLVGNKCDLTTKKVVDYTT 138
           ++RGA   ++VYDVT + SF      W + + +   E    + VG+K DL   +V+    
Sbjct: 331 HFRGAQVALLVYDVTCEWSFLTATTVWRKALMKNIPE-AQVIFVGSKTDLEENRVISTER 155

Query: 139 AKEFADSLGIPFLETSAKNATNVEQSFMTMA 169
            + FA   G  F ETS+    NV+  F  +A
Sbjct: 154 GQAFATQCGYTFFETSSVTGKNVDAVFWEIA 62
>13745
          Length = 1045

 Score = 70.9 bits (172), Expect = 3e-13,   Method: Compositional matrix adjust.
 Identities = 40/104 (38%), Positives = 58/104 (55%), Gaps = 4/104 (3%)
 Frame = +2

Query: 70  QERFRTITSSYYRGAHGIIVVYDVTDQESFNNVKQWLQEIDRYAS----ENVNKLLVGNK 125
           QERF+++  ++YRGA   ++VYDVT   SF N+  W  E    AS    E+   +++GNK
Sbjct: 2   QERFQSLGVAFYRGADCCVLVYDVTAPNSFKNLDSWRDEFLIQASPRDPEHFPFVVLGNK 181

Query: 126 CDLTTKKVVDYTTAKEFADSLGIPFLETSAKNATNVEQSFMTMA 169
            DL  ++V      +       IP+ ETSAK   NVE +F T+A
Sbjct: 182 VDLDNRQVSTRRAQQWCQSKNDIPYYETSAKEGINVEMAFQTIA 313
>34359
          Length = 1042

 Score = 68.2 bits (165), Expect = 3e-12,   Method: Compositional matrix adjust.
 Identities = 37/122 (30%), Positives = 66/122 (54%)
 Frame = +3

Query: 12  FKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQE 71
           FKL+L+G      + ++ R    +  + Y++T+GV+            ++  +WDTAGQE
Sbjct: 54  FKLVLVGGRWEWANNIVKRHVTGS*-KKYVATLGVEVHPLQFNTSRGLLRFNVWDTAGQE 230

Query: 72  RFRTITSSYYRGAHGIIVVYDVTDQESFNNVKQWLQEIDRYASENVNKLLVGNKCDLTTK 131
           +F  +   YY      I+++DVT + ++ NV  W +++ R   EN+  +L GNK D+  +
Sbjct: 231 KFGGLRDGYYIQGTCAIIMFDVTSRVTYKNVPNWHRDLVR-VCENIPIVLCGNKVDIKDR 407

Query: 132 KV 133
           KV
Sbjct: 408 KV 413
>19656
          Length = 428

 Score = 67.4 bits (163), Expect = 4e-12,   Method: Compositional matrix adjust.
 Identities = 30/103 (29%), Positives = 55/103 (53%), Gaps = 1/103 (0%)
 Frame = +3

Query: 13  KLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQER 72
           K +++GD  VGK+CLL+ +  + +   YI T+  D     + +DG+ + L +WDTAGQE 
Sbjct: 117 KCVVVGDGAVGKTCLLISYTTNAFPGEYIPTV-FDNYSANVMVDGRPVNLGLWDTAGQED 293

Query: 73  FRTITSSYYRGAHGIIVVYDVTDQESFNNVK-QWLQEIDRYAS 114
           +  +    Y      ++ + V    SF N++ +W  E++ +  
Sbjct: 294 YDRLRPLSYPQTDVFLLCFSVASPASFENIRAKWYPEVNHHCP 422
>29380
          Length = 853

 Score = 62.4 bits (150), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 35/102 (34%), Positives = 58/102 (56%), Gaps = 1/102 (0%)
 Frame = -2

Query: 84  AHGIIVVYDVTDQESFNNVKQWLQEIDRYASENVNKLLVGNKCDLTTK-KVVDYTTAKEF 142
           A   I+VYDV   ++F+    W++E+ +  +E+V  +L GNK DL T+ + V +  A+ F
Sbjct: 852 ASAAIIVYDVNIADTFSRALAWVKELRQQNTESVLIILAGNKVDLATQHRAVSFEDAQSF 673

Query: 143 ADSLGIPFLETSAKNATNVEQSFMTMAAEIKKRMGPGATAGG 184
           A   G+ F E SAK    V + FMT+A ++ ++   G+   G
Sbjct: 672 ARENGLLFAEVSAKTGMAVNEIFMTLANQLIQQEIDGSRNRG 547
>09204
          Length = 1051

 Score = 60.5 bits (145), Expect = 5e-10,   Method: Compositional matrix adjust.
 Identities = 33/107 (30%), Positives = 54/107 (50%), Gaps = 4/107 (3%)
 Frame = -3

Query: 72   RFRTITSSYYRGAHGIIVVYDVTDQESFNNVKQWLQEIDRYASENVNKLLVGNKCDLT-- 129
            R+  ++  YYRGA   I+ +D+TD+ SF+ ++ W+ E+ R   E     + G K DL   
Sbjct: 1049 RYEAMSRIYYRGAKAAILCFDLTDKSSFDRIRFWIGEL-RQHEEECKLYICGTKFDLVHD 873

Query: 130  --TKKVVDYTTAKEFADSLGIPFLETSAKNATNVEQSFMTMAAEIKK 174
               ++ V  + AK  AD       ETS+    N+E+ F  +A +  K
Sbjct: 872  DPERRAVPRSVAKALADDCMAEIYETSSMTGDNIEKLFTKIAEDYMK 732
>19046
          Length = 445

 Score = 58.2 bits (139), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 34/106 (32%), Positives = 55/106 (51%), Gaps = 2/106 (1%)
 Frame = -2

Query: 70  QERFRTITSSYYRGAHGIIVVYDVTDQESFNNVKQWLQEIDRYA-SENVNKLLVGNKCDL 128
           QE F  +   Y R   G ++V+ VTD  SF N+  +  +I R    ++   +L  NK DL
Sbjct: 444 QEEFSAMREQYMRKGDGFLLVFSVTDFRSFENMANFHTQILRVKDRDSYPMILCANKVDL 265

Query: 129 TTKKVVDYTTAKEFADSLGIPFLETSAKNAT-NVEQSFMTMAAEIK 173
             ++ V     ++ A  L IP++ETSAK+   NV+ +F  +   I+
Sbjct: 264 VHQRKVSEEQVRDLATRLRIPYIETSAKDPPLNVDLAFHQVVRVIR 127
>24619
          Length = 509

 Score = 57.0 bits (136), Expect = 5e-09,   Method: Compositional matrix adjust.
 Identities = 33/106 (31%), Positives = 54/106 (50%), Gaps = 2/106 (1%)
 Frame = -2

Query: 70  QERFRTITSSYYRGAHGIIVVYDVTDQESFNNVKQWLQEIDRYASENVNKL-LVGNKCDL 128
           QE F  +   Y R   G ++V+ V D +SF N+  +  +I R    +   + L  NK DL
Sbjct: 508 QEEFSAMREQYMRKGDGFLLVFSVIDYQSFENMVNFHTQILRVKDRDTYPMILCANKVDL 329

Query: 129 TTKKVVDYTTAKEFADSLGIPFLETSAKNAT-NVEQSFMTMAAEIK 173
             ++ V     ++ A  L IP++ETSAK+   NV+ +F  +   I+
Sbjct: 328 VHQRKVSEEQVRDLATRLRIPYIETSAKDPPLNVDLAFHQVVRVIR 191
>08153
          Length = 1703

 Score = 55.1 bits (131), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 43/146 (29%), Positives = 71/146 (48%), Gaps = 6/146 (4%)
 Frame = +1

Query: 13  KLLLIGDSGVGKSCLL--LRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQ 70
           ++L++G    GK+ +L  L+  +   T   I TIG  F + T+E   K I   +WD  GQ
Sbjct: 88  RILMVGLDAAGKTTILYKLKLGEIVTT---IPTIG--FNVETVEY--KNISFTVWDVGGQ 246

Query: 71  ERFRTITSSYYRGAHGIIVVYDVTDQESFNNVKQWLQEIDRYASENVNK----LLVGNKC 126
           ++ R +   Y++   G+I V D  D+E  N  K   +E+ R  +E+  +    L+  NK 
Sbjct: 247 DKIRPLWRHYFQNTQGLIFVVDSNDRERINEAK---EELARMLNEDDLRDAIILVFANKQ 417

Query: 127 DLTTKKVVDYTTAKEFADSLGIPFLE 152
           DL      +  +A E    LG+  L+
Sbjct: 418 DLP-----NAYSASEVTAHLGLANLK 480
>14119
          Length = 602

 Score = 52.4 bits (124), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 32/96 (33%), Positives = 53/96 (55%), Gaps = 1/96 (1%)
 Frame = +1

Query: 98  SFNNVKQWLQEIDRYASENVNKLLVGNKCDLTTK-KVVDYTTAKEFADSLGIPFLETSAK 156
           +FN    W++E+ +  + +V  +L GNK DL ++ + V    A+ FA+  G+ F E SAK
Sbjct: 1   TFNRALAWVKELRQQNAGSVLIVLAGNKADLASEHRAVSADDARTFAEDNGLIFAEVSAK 180

Query: 157 NATNVEQSFMTMAAEIKKRMGPGATAGGAEKSNVKI 192
               V + FMT+A ++ +R    A  GG   S V++
Sbjct: 181 TGMAVSEVFMTIAHKLVRR----AEEGGGVWSGVQV 276
>09827
          Length = 1201

 Score = 52.4 bits (124), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 37/122 (30%), Positives = 63/122 (51%), Gaps = 6/122 (4%)
 Frame = -3

Query: 13   KLLLIGDSGVGKSCLL--LRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQ 70
            ++L++G    GK+ +L  L+  +   T   I TIG  F + T+E   K I   +WD  GQ
Sbjct: 1109 RILMVGLDAAGKTTILYKLKLGEIVTT---IPTIG--FNVETVEY--KNISFTVWDVGGQ 951

Query: 71   ERFRTITSSYYRGAHGIIVVYDVTDQESFNNVKQWLQEIDRYASENVNK----LLVGNKC 126
            ++ R +   Y++   G+I V D  D+E    V++  +E+ R  +E+  +    L+  NK 
Sbjct: 950  DKIRPLWRHYFQNTQGLIFVVDSNDKE---RVQEAREELTRMLNEDELRDAVLLVFANKQ 780

Query: 127  DL 128
            DL
Sbjct: 779  DL 774
>25618
          Length = 475

 Score = 49.7 bits (117), Expect = 9e-07,   Method: Compositional matrix adjust.
 Identities = 27/86 (31%), Positives = 48/86 (55%), Gaps = 1/86 (1%)
 Frame = +3

Query: 120 LLVGNKCDLTTK-KVVDYTTAKEFADSLGIPFLETSAKNATNVEQSFMTMAAEIKKRMGP 178
           +L GNK DL ++ + V    A+ FA+  G+ F E SAK    V + FMT+A ++ +R   
Sbjct: 87  VLAGNKADLASEHRAVSADDARTFAEDNGLIFAEVSAKTGMAVSEVFMTIAHKLVRRAEE 266

Query: 179 GATAGGAEKSNVKIQSTPVKQSGGGC 204
           G    G+ +   +++ +  +++ GGC
Sbjct: 267 GQ---GSXQGRERVRLSEAEEASGGC 335
>00552
          Length = 455

 Score = 48.5 bits (114), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 22/53 (41%), Positives = 34/53 (64%)
 Frame = -1

Query: 11  LFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQ 63
           L K++L+GD GVGKS L+ RF  + +      TIGV+F  + + +DG+T  +Q
Sbjct: 446 LLKVVLLGDGGVGKSSLMNRFVSNKFDAQSFHTIGVEFLTKDVVVDGETFTMQ 288

 Score = 45.4 bits (106), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 17/49 (34%), Positives = 30/49 (61%)
 Frame = -3

Query: 64  IWDTAGQERFRTITSSYYRGAHGIIVVYDVTDQESFNNVKQWLQEIDRY 112
           IWDTAGQER++++ + +YRG    ++ + V + +S  ++  W  E   Y
Sbjct: 147 IWDTAGQERYKSLRTPFYRGTDCCLLTFSVDNLKSLQSLSDWYDEFVNY 1
>14775
          Length = 380

 Score = 47.4 bits (111), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 27/75 (36%), Positives = 44/75 (58%), Gaps = 4/75 (5%)
 Frame = -2

Query: 24  KSCLLLRFADDTYTESYISTIGV---DF-KIRTIELDGKTIKLQIWDTAGQERFRTITSS 79
           K+CLL R+    + +  + TI V   +F + RT   D   ++  +WDT G E +R++  S
Sbjct: 379 KTCLLRRYQKGFFMDRTMPTIAVLCSEFNESRT---DPLNVRYTLWDTGGAETYRSLWVS 209

Query: 80  YYRGAHGIIVVYDVT 94
           ++RGA   ++VYDVT
Sbjct: 208 HFRGAQVALLVYDVT 164
>10862
          Length = 2896

 Score = 47.4 bits (111), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 33/135 (24%), Positives = 55/135 (40%), Gaps = 2/135 (1%)
 Frame = -3

Query: 19   DSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRTITS 78
            D  VG  C    ++        +     + +I+      +  +  +WD  GQ++ R +  
Sbjct: 2609 DPHVGA*CCRENYSSIQNETRTVCDXNTNSRIQCRNCQLQECQFNVWDVGGQDKIRPLWR 2430

Query: 79   SYYRGAHGIIVVYDVTDQESFNNVKQWLQEI--DRYASENVNKLLVGNKCDLTTKKVVDY 136
             YY G  G+I V D  D++  +  +Q L  I  DR   + +  L+  NK DL      D 
Sbjct: 2429 HYYTGTQGLIFVVDCADRDRIDEARQELHRIINDREMRDAI-ILIFANKQDLP-----DA 2268

Query: 137  TTAKEFADSLGIPFL 151
                E  + LG+  L
Sbjct: 2267 MKPHEIQEKLGLTRL 2223
>33605
          Length = 888

 Score = 47.4 bits (111), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 30/93 (32%), Positives = 50/93 (53%), Gaps = 1/93 (1%)
 Frame = +1

Query: 13  KLLLIGDSGVGKSCLLLRF-ADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQE 71
           +LL++G    GK+ +L +F  +D  T S   T+G  F I+T+E  G   KL +WD  GQ+
Sbjct: 502 RLLMLGLDNAGKTTILKKFNGEDIDTIS--PTLG--FNIKTLEHRG--FKLNVWDVGGQQ 663

Query: 72  RFRTITSSYYRGAHGIIVVYDVTDQESFNNVKQ 104
             R+   +Y+    G++ V D  D+    + K+
Sbjct: 664 SLRSYWRNYFESTDGLVWVVDSADRMRIADCKR 762
>18509
          Length = 625

 Score = 47.0 bits (110), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 24/61 (39%), Positives = 36/61 (59%)
 Frame = -3

Query: 114 SENVNKLLVGNKCDLTTKKVVDYTTAKEFADSLGIPFLETSAKNATNVEQSFMTMAAEIK 173
           ++ V  +LVGNK DL  + V +    K  A+   IP++ETSAK    V+ +F T+  EI+
Sbjct: 536 ADEVPMVLVGNKVDLPIRNV-EQRQGKHMAELYHIPYVETSAKTRQGVDDAFYTLVREIR 360

Query: 174 K 174
           K
Sbjct: 359 K 357
>31291
          Length = 446

 Score = 46.2 bits (108), Expect = 9e-06,   Method: Compositional matrix adjust.
 Identities = 26/72 (36%), Positives = 38/72 (52%), Gaps = 1/72 (1%)
 Frame = -1

Query: 62  LQIWDTAGQERFRTITSSYYRGAHGIIVVYDVTDQESFNNVK-QWLQEIDRYASENVNKL 120
           LQ+WDTAGQE +  +    Y      ++ + +  + S  NVK +W  EI R+   +V  +
Sbjct: 446 LQLWDTAGQEDYDRLRPLAYPNTDVFMLXFSLMSEASMKNVKVKWYPEI-RHHDPHVPIV 270

Query: 121 LVGNKCDLTTKK 132
           LVG K DL   K
Sbjct: 269 LVGTKLDLRQDK 234
>25796
          Length = 422

 Score = 43.9 bits (102), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 18/30 (60%), Positives = 23/30 (76%)
 Frame = -1

Query: 2  SSMNPEYDYLFKLLLIGDSGVGKSCLLLRF 31
          ++M+  YDYLFK L+IG +G GKSCLL  F
Sbjct: 95 NNMSETYDYLFKFLIIGSAGSGKSCLLHHF 6
>12443
          Length = 837

 Score = 39.7 bits (91), Expect = 9e-04,   Method: Compositional matrix adjust.
 Identities = 31/133 (23%), Positives = 67/133 (50%), Gaps = 9/133 (6%)
 Frame = -3

Query: 12  FKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVD----FKIRTIELDGKTI--KLQIW 65
           +K++L+G +GVGK+  + +   +    ++  T G+     +    I+  GKT+  ++Q++
Sbjct: 580 YKVMLVGKTGVGKTSTVAKLTGNDIPLTHNETPGLQTSHLYWPGKIKHLGKTVLFQIQLF 401

Query: 66  DTAGQ---ERFRTITSSYYRGAHGIIVVYDVTDQESFNNVKQWLQEIDRYASENVNKLLV 122
           D AG+   +R+  I  +   G  GI+ ++   D+ SF+ + Q L        + + K+ +
Sbjct: 400 D-AGETALKRYDHILPACQDGVDGIMFLFSFVDKGSFDEIPQLLTRFTT-LEDGICKIAL 227

Query: 123 GNKCDLTTKKVVD 135
           G K     K +++
Sbjct: 226 GTKYPFPHKGIIN 188
>10708
          Length = 2775

 Score = 34.3 bits (77), Expect = 0.039,   Method: Compositional matrix adjust.
 Identities = 12/47 (25%), Positives = 25/47 (53%)
 Frame = -2

Query: 58   KTIKLQIWDTAGQERFRTITSSYYRGAHGIIVVYDVTDQESFNNVKQ 104
            + ++L +WDTAGQE +  +    Y     I++ + +   +S  N+ +
Sbjct: 2729 QQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPE 2589
>31928
          Length = 429

 Score = 33.5 bits (75), Expect = 0.061,   Method: Compositional matrix adjust.
 Identities = 24/78 (30%), Positives = 41/78 (52%), Gaps = 5/78 (6%)
 Frame = +2

Query: 53  IELD-GKTIKLQIWDTAGQERFRT---ITSSYYRGAHGIIVVYDVTDQESFNNVKQWLQE 108
           IE D G   K++I+DT       T   +   Y     G ++VYD T  ESF  + +  ++
Sbjct: 80  IETDRGVKEKVRIFDTGAAALETTEGDLPKHYLNFPDGFVLVYDTTSWESFRRLDKLKKD 259

Query: 109 IDRYASEN-VNKLLVGNK 125
           ID++  +  V+ +++GNK
Sbjct: 260 IDKHRDKREVHMIVIGNK 313
>06994
          Length = 429

 Score = 30.8 bits (68), Expect = 0.38,   Method: Compositional matrix adjust.
 Identities = 18/86 (20%), Positives = 34/86 (39%), Gaps = 32/86 (37%)
 Frame = +1

Query: 51  RTIELDGKTIKLQIWDTAG--------------------------------QERFRTITS 78
           + +E+DG+   L+I DTAG                                 E+F  +  
Sbjct: 172 KQVEVDGQQCMLEILDTAGTVHASHSNACVHGSLHAFVGTVTPLGRDALLNTEQFTAMRD 351

Query: 79  SYYRGAHGIIVVYDVTDQESFNNVKQ 104
            Y +   G ++ Y +T Q +FN++++
Sbjct: 352 LYMKNGQGFLLAYSITAQSTFNDLQE 429
>18184
          Length = 558

 Score = 30.0 bits (66), Expect = 0.74,   Method: Compositional matrix adjust.
 Identities = 13/36 (36%), Positives = 21/36 (58%)
 Frame = -3

Query: 10  YLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIG 45
           YLF +LL G    G  CL+  F  +++   ++ST+G
Sbjct: 442 YLFYILLTGIVQFGYCCLVGTFPFNSFLAGFVSTVG 335
>28005
          Length = 753

 Score = 27.3 bits (59), Expect = 4.8,   Method: Compositional matrix adjust.
 Identities = 11/39 (28%), Positives = 20/39 (51%)
 Frame = -1

Query: 23  GKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIK 61
            K CL++      Y  S++S +GV F +   ++ G+  K
Sbjct: 363 AKHCLVMHRLGHLYVISHLSCVGVMFVLSVFDIIGRLCK 247
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|34328471|ref|NP_062364.3| ras related v-ral simian
leukemia viral oncogene homolog A [Mus musculus]
         (206 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

07580                                                                 147   8e-41
00858                                                                 161   2e-40
26536                                                                  99   2e-21
19046                                                                  99   2e-21
24619                                                                  95   2e-20
14456                                                                  92   1e-19
08428                                                                  92   2e-19
11257                                                                  86   8e-18
34468                                                                  86   1e-17
36482                                                                  77   4e-15
33374                                                                  77   5e-15
18509                                                                  64   6e-15
17511                                                                  77   6e-15
11728                                                                  77   6e-15
19006                                                                  76   1e-14
06994                                                                  55   4e-14
07465                                                                  74   4e-14
19656                                                                  70   6e-13
26083                                                                  69   2e-12
01972                                                                  68   2e-12
33380                                                                  65   2e-11
33794                                                                  65   2e-11
13750                                                                  65   2e-11
01398                                                                  64   6e-11
05468                                                                  60   5e-10
34359                                                                  58   3e-09
32723                                                                  57   5e-09
01095                                                                  54   7e-08
13745                                                                  53   9e-08
13901                                                                  49   1e-06
35581                                                                  47   4e-06
12339                                                                  47   5e-06
34597                                                                  47   8e-06
17872                                                                  46   1e-05
31291                                                                  45   3e-05
00552                                                                  37   0.004
10708                                                                  36   0.011
09700                                                                  34   0.038
31932                                                                  33   0.092
09827                                                                  33   0.11 
11378                                                                  32   0.20 
32770                                                                  31   0.32 
08153                                                                  31   0.34 
31928                                                                  31   0.44 
33605                                                                  30   0.59 
31774                                                                  28   2.3  
14775                                                                  28   3.4  
22274                                                                  27   5.4  
>07580
          Length = 921

 Score =  147 bits (371), Expect(2) = 8e-41,   Method: Compositional matrix adjust.
 Identities = 69/140 (49%), Positives = 101/140 (72%)
 Frame = +3

Query: 39  FVEDYEPTKADSYRKKVVLDGEEVQIDILDTAGQEDYAAIRDNYFRSGEGFLCVFSITEM 98
           FVE Y+PT  DSYRK+V +DG++  ++ILDTAG E + A+RD Y ++G+GFL  +SIT  
Sbjct: 135 FVEKYDPTIEDSYRKQVEVDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFLLAYSITAQ 314

Query: 99  ESFAATADFREQILRVKEDENVPFLLVGNKSDLEDKRQVSVEEAKNRADQWNVNYVETSA 158
            +F    + REQILRVK+ ++VP LLVGNK DLED+R V  ++ +  A  ++  ++ETSA
Sbjct: 315 STFNDLQELREQILRVKDTDDVPMLLVGNKCDLEDERVVGKDQGQGLARSFSCAFLETSA 494

Query: 159 KTRANVDKVFFDLMREIRAR 178
           K R NV+++F DL+R+I  +
Sbjct: 495 KARINVNEIFMDLVRQINKK 554

 Score = 36.6 bits (83), Expect(2) = 8e-41,   Method: Compositional matrix adjust.
 Identities = 15/25 (60%), Positives = 23/25 (92%)
 Frame = +2

Query: 15 HKVIMVGSGGVGKSALTLQFMYDEF 39
          +K++++GSGGVGKSALT+QF+  +F
Sbjct: 62 YKLVVLGSGGVGKSALTVQFVQGDF 136
>00858
          Length = 1658

 Score =  161 bits (407), Expect = 2e-40,   Method: Compositional matrix adjust.
 Identities = 80/149 (53%), Positives = 107/149 (71%)
 Frame = -2

Query: 27   KSALTLQFMYDEFVEDYEPTKADSYRKKVVLDGEEVQIDILDTAGQEDYAAIRDNYFRSG 86
            KSALT+Q   + FVE+Y+PT  DS RK+VV+DGE   +DILDTAGQE+ +A+RD   R+G
Sbjct: 1552 KSALTIQLXQNHFVEEYDPTXEDSXRKQVVIDGETCLLDILDTAGQEEXSAMRDQCMRTG 1373

Query: 87   EGFLCVFSITEMESFAATADFREQILRVKEDENVPFLLVGNKSDLEDKRQVSVEEAKNRA 146
            EGFLCVF++  ++SF     +REQI RVK+ + VP +LVGNK DL   R V   + K+ A
Sbjct: 1372 EGFLCVFAVXNLKSFEDINQYREQIKRVKDADEVPMVLVGNKVDLP-IRNVEQRQGKHMA 1196

Query: 147  DQWNVNYVETSAKTRANVDKVFFDLMREI 175
            + +++ YVETSAKTR  VD  F+ L+REI
Sbjct: 1195 ELYHIPYVETSAKTRQGVDDAFYTLVREI 1109
>26536
          Length = 829

 Score = 98.6 bits (244), Expect = 2e-21,   Method: Compositional matrix adjust.
 Identities = 51/115 (44%), Positives = 79/115 (68%), Gaps = 1/115 (0%)
 Frame = +2

Query: 62  VQIDILDTAGQEDYAAIRDNYFRSGEGFLCVFSITEMESFA-ATADFREQILRVKEDENV 120
           V    LDTAGQE+Y+++R++Y RSG+GF+ V+S+T++ SF  A A FR  + R +++ ++
Sbjct: 128 VSWTFLDTAGQEEYSSMREHYTRSGDGFIVVYSVTDVTSFQEAEAVFR-WLTRFQDETSI 304

Query: 121 PFLLVGNKSDLEDKRQVSVEEAKNRADQWNVNYVETSAKTRANVDKVFFDLMREI 175
             +L GNK+DL   R+V+ EE +  AD+  + Y ETSAKT  NV +V+  L+R I
Sbjct: 305 HAVLCGNKTDLTSDRKVTPEEGRKMADRLGMLYFETSAKTGDNVSQVYHGLLRSI 469

 Score = 58.9 bits (141), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 24/46 (52%), Positives = 37/46 (80%)
 Frame = +2

Query: 15  HKVIMVGSGGVGKSALTLQFMYDEFVEDYEPTKADSYRKKVVLDGE 60
           +K++M+GSGGVGKS+LT++F  D F++ Y+PT  DSYRK + + G+
Sbjct: 488 YKIVMLGSGGVGKSSLTIRFTQDTFLDVYDPTIEDSYRKMIQVSGQ 625
>19046
          Length = 445

 Score = 98.6 bits (244), Expect = 2e-21,   Method: Compositional matrix adjust.
 Identities = 49/108 (45%), Positives = 73/108 (67%), Gaps = 1/108 (0%)
 Frame = -2

Query: 72  QEDYAAIRDNYFRSGEGFLCVFSITEMESFAATADFREQILRVKEDENVPFLLVGNKSDL 131
           QE+++A+R+ Y R G+GFL VFS+T+  SF   A+F  QILRVK+ ++ P +L  NK DL
Sbjct: 444 QEEFSAMREQYMRKGDGFLLVFSVTDFRSFENMANFHTQILRVKDRDSYPMILCANKVDL 265

Query: 132 EDKRQVSVEEAKNRADQWNVNYVETSAK-TRANVDKVFFDLMREIRAR 178
             +R+VS E+ ++ A +  + Y+ETSAK    NVD  F  ++R IRA+
Sbjct: 264 VHQRKVSEEQVRDLATRLRIPYIETSAKDPPLNVDLAFHQVVRVIRAQ 121
>24619
          Length = 509

 Score = 95.1 bits (235), Expect = 2e-20,   Method: Compositional matrix adjust.
 Identities = 47/108 (43%), Positives = 71/108 (65%), Gaps = 1/108 (0%)
 Frame = -2

Query: 72  QEDYAAIRDNYFRSGEGFLCVFSITEMESFAATADFREQILRVKEDENVPFLLVGNKSDL 131
           QE+++A+R+ Y R G+GFL VFS+ + +SF    +F  QILRVK+ +  P +L  NK DL
Sbjct: 508 QEEFSAMREQYMRKGDGFLLVFSVIDYQSFENMVNFHTQILRVKDRDTYPMILCANKVDL 329

Query: 132 EDKRQVSVEEAKNRADQWNVNYVETSAK-TRANVDKVFFDLMREIRAR 178
             +R+VS E+ ++ A +  + Y+ETSAK    NVD  F  ++R IRA+
Sbjct: 328 VHQRKVSEEQVRDLATRLRIPYIETSAKDPPLNVDLAFHQVVRVIRAQ 185
>14456
          Length = 1867

 Score = 92.0 bits (227), Expect = 1e-19,   Method: Compositional matrix adjust.
 Identities = 56/159 (35%), Positives = 92/159 (57%), Gaps = 5/159 (3%)
 Frame = -1

Query: 23   GGVGKSALTLQFMYDEF-VEDYEPTKADSYRKKVVLDGEEVQIDILDTAGQEDYAAIRDN 81
            GGVGKS+L  +F+ ++F  + +     +   K VV+D E   + I DTAGQE + ++R  
Sbjct: 1114 GGVGKSSLMNRFVSNKFDAQSFHTIGVEFLNKDVVVDDETYTMQIWDTAGQERFKSLRTP 935

Query: 82   YFRSGEGFLCVFSITEMESFAATADFREQILR---VKEDENVPFLLVGNKSDLEDKRQVS 138
            ++R  +  L  FS+  M+SF   + +R++ L    +++    PF+++GNK D+E  RQV+
Sbjct: 934  FYRGADCCLLTFSVDSMQSFRNLSMWRKEFLYYADIQDGVTFPFVVLGNKIDVEG-RQVT 758

Query: 139  VEEAKNRAD-QWNVNYVETSAKTRANVDKVFFDLMREIR 176
             EEA++      N  Y ETSAK   NV+K F   ++ +R
Sbjct: 757  NEEARSWCTANSNAPYFETSAKDATNVEKAFLAAVQRLR 641
>08428
          Length = 1109

 Score = 92.0 bits (227), Expect = 2e-19,   Method: Compositional matrix adjust.
 Identities = 53/161 (32%), Positives = 90/161 (55%), Gaps = 1/161 (0%)
 Frame = -3

Query: 16   KVIMVGSGGVGKSALTLQFMYDEFVEDYEPTKADSY-RKKVVLDGEEVQIDILDTAGQED 74
            KV ++G  GVGKS++ L+F+   +    E T   S+  K +V+DG   +  I DTAGQE 
Sbjct: 1065 KVCLLGDSGVGKSSIVLRFVTGSYRPSQESTIGASFMSKSLVVDGAGYRFQIWDTAGQEK 886

Query: 75   YAAIRDNYFRSGEGFLCVFSITEMESFAATADFREQILRVKEDENVPFLLVGNKSDLEDK 134
            + A+   Y+R     + V+ +T   +F +   + ++ LR     N+   + GNK DLE+ 
Sbjct: 885  FRALAPMYYRGAAAAVIVYDVTRPRTFKSVKSWIQE-LRSFGPPNIVLAIAGNKCDLEEL 709

Query: 135  RQVSVEEAKNRADQWNVNYVETSAKTRANVDKVFFDLMREI 175
            R+V  ++A+  A   +  + ETSA T  NV+++F +L R++
Sbjct: 708  REVVEKDAQEYASSISAIFGETSAMTAVNVEEMFTELARQL 586
>11257
          Length = 1102

 Score = 86.3 bits (212), Expect = 8e-18,   Method: Compositional matrix adjust.
 Identities = 46/129 (35%), Positives = 79/129 (61%), Gaps = 4/129 (3%)
 Frame = -2

Query: 52   RKKVVLDGEEVQIDILDTAGQEDYAAIRDNYFRSGEGFLCVFSITEMESFAATADFREQI 111
             K VV+DGE   + I DTAGQE Y ++R  ++R  +  L  FS+  ++S  + +D+ ++ 
Sbjct: 1056 HKDVVVDGETFTMQIWDTAGQERYKSLRTPFYRGTDCCLLTFSVDNLKSLQSLSDWYDEF 877

Query: 112  LR---VKEDENVPFLLVGNKSDLEDKRQVSVEEAKNRA-DQWNVNYVETSAKTRANVDKV 167
            +    +++  + PF+++GNK+D+E +R+VS E+A N      N+ Y ETSAK   NV + 
Sbjct: 876  VNYADIQDSASFPFVIIGNKADIE-EREVSSEDAYNWCRTHGNLPYFETSAKDSLNVQQA 700

Query: 168  FFDLMREIR 176
            F  ++R +R
Sbjct: 699  FLAVVRRLR 673
>34468
          Length = 1502

 Score = 85.9 bits (211), Expect = 1e-17,   Method: Compositional matrix adjust.
 Identities = 54/173 (31%), Positives = 97/173 (56%), Gaps = 5/173 (2%)
 Frame = +1

Query: 9   QNSLALHKVIMVGSGGVGKSALTLQFMYDEFVEDYEPTKADSYRKKVV-LDGEEVQIDIL 67
           Q    + K+I++G   VGK+ LT +F   +F +  E T    +R+K + +D E +++ + 
Sbjct: 478 QTQRRIFKIIVIGDSNVGKTCLTYRFCLGKFPDKTEATIGVDFREKSIQVDSEHLKLQLW 657

Query: 68  DTAGQEDY-AAIRDNYFRSGEGFLCVFSITEMESFAATADFREQILRVKEDENVPFLLVG 126
           DTAGQE +  ++  +Y+R+    + V+ +T+M SF     + E+  R    + +P +LVG
Sbjct: 658 DTAGQERFRKSMVQHYYRNVHAVVFVYDMTKMSSFENMPAWIEECDRHNLTKYIPRILVG 837

Query: 127 NKSDLEDKRQVSVEEAKNRADQWNVNYVETSAK--TRAN-VDKVFFDLMREIR 176
           NK D+ ++  V+   A+  AD  N+   ETSAK   +AN VD +F  +  +++
Sbjct: 838 NKCDVVERIAVNTNLAQKFADAHNMPLFETSAKDDEKANHVDAIFMTVAHKLK 996
>36482
          Length = 686

 Score = 77.4 bits (189), Expect = 4e-15,   Method: Compositional matrix adjust.
 Identities = 45/150 (30%), Positives = 84/150 (56%), Gaps = 3/150 (2%)
 Frame = +2

Query: 30  LTLQFMYDEFVEDYEPTKADSYRKKVVLDGEEVQIDILDTAGQEDYAAIRDNYFRSGEGF 89
           LT++F+   F+ +Y PT    Y+   V++ ++V+++ILDTAGQ  Y   ++ Y    + F
Sbjct: 2   LTVRFLTRRFIGEYCPTLESVYKYHTVIEDDDVRLEILDTAGQGTY-PWKEGYALWADCF 178

Query: 90  LCVFSITEMESFAATADFREQILRVKEDENVPFLLVGNKSDLEDKRQVSVEEAKNRADQW 149
           + V+SI + +S+      + Q+  V++  ++  +L  NK+DL   RQV+ +E ++ A++ 
Sbjct: 179 VFVYSINDRQSYEELVQVKRQVESVRKSTSLTAVLAANKTDLLHDRQVTQKEGEDLAEEI 358

Query: 150 NVNYVETSAKTRANVDKV---FFDLMREIR 176
                E SA   + ++ +   F DL RE R
Sbjct: 359 GCRLYEVSASEGSQMEAITSMFHDLYREFR 448
>33374
          Length = 489

 Score = 77.0 bits (188), Expect = 5e-15,   Method: Compositional matrix adjust.
 Identities = 41/115 (35%), Positives = 69/115 (60%)
 Frame = +1

Query: 53  KKVVLDGEEVQIDILDTAGQEDYAAIRDNYFRSGEGFLCVFSITEMESFAATADFREQIL 112
           + V LD   V+ +I DTAGQE Y ++   Y+R  +  + V+ IT  ++F     + +++ 
Sbjct: 148 QTVCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNQDTFGRAKTWVKELQ 327

Query: 113 RVKEDENVPFLLVGNKSDLEDKRQVSVEEAKNRADQWNVNYVETSAKTRANVDKV 167
           R +   N+   L GNK+DL +KR V  EEA+  A++ ++ ++ETSAKT  NV+ +
Sbjct: 328 R-QASPNIVIALAGNKADLANKRMVEFEEAQAYAEENSLLFMETSAKTAMNVNDI 489
>18509
          Length = 625

 Score = 63.5 bits (153), Expect(2) = 6e-15,   Method: Compositional matrix adjust.
 Identities = 33/64 (51%), Positives = 44/64 (68%)
 Frame = -3

Query: 113 RVKEDENVPFLLVGNKSDLEDKRQVSVEEAKNRADQWNVNYVETSAKTRANVDKVFFDLM 172
           RVK+ + VP +LVGNK DL   R V   + K+ A+ +++ YVETSAKTR  VD  F+ L+
Sbjct: 548 RVKDADEVPMVLVGNKVDLP-IRNVEQRQGKHMAELYHIPYVETSAKTRQGVDDAFYTLV 372

Query: 173 REIR 176
           REIR
Sbjct: 371 REIR 360

 Score = 33.1 bits (74), Expect(2) = 6e-15,   Method: Compositional matrix adjust.
 Identities = 13/25 (52%), Positives = 18/25 (72%)
 Frame = -1

Query: 87  EGFLCVFSITEMESFAATADFREQI 111
           EGFLCVF++  ++SF     +REQI
Sbjct: 625 EGFLCVFAVNNLKSFEDINQYREQI 551
>17511
          Length = 483

 Score = 76.6 bits (187), Expect = 6e-15,   Method: Compositional matrix adjust.
 Identities = 43/123 (34%), Positives = 73/123 (59%), Gaps = 4/123 (3%)
 Frame = -3

Query: 13  ALHKVIMVGSGGVGKSALTLQFMYDEFVEDYEPT-KADSYRKKVVLDGEEVQIDILDTAG 71
            L KVI++G  GVGK++L  Q++  +F   Y+ T  AD   K+V++D   V + I DTAG
Sbjct: 370 VLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQIWDTAG 191

Query: 72  QEDYAAIRDNYFRSGEGFLCVFSITEMESFAATADFREQIL---RVKEDENVPFLLVGNK 128
           QE + ++   ++R  +  + VF +T   +F +   +R++ L     ++ EN PF+++GNK
Sbjct: 190 QERFQSLGVAFYRGADCCVLVFDVTMPNTFRSLDSWRDEFLIQASPRDPENFPFVVIGNK 11

Query: 129 SDL 131
            DL
Sbjct: 10  IDL 2
>11728
          Length = 635

 Score = 76.6 bits (187), Expect = 6e-15,   Method: Compositional matrix adjust.
 Identities = 42/131 (32%), Positives = 71/131 (54%), Gaps = 1/131 (0%)
 Frame = -1

Query: 16  KVIMVGSGGVGKSALTLQFMYDEFVEDYEPTKADSYRKKVVLDGEEVQIDILDTAGQEDY 75
           K ++VG G VGK+ L + +  + F  +Y PT  D+Y   V++D + + + + DTAGQEDY
Sbjct: 485 KCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDSKPINLGLWDTAGQEDY 306

Query: 76  AAIRDNYFRSGEGFLCVFSITEMESFA-ATADFREQILRVKEDENVPFLLVGNKSDLEDK 134
             +R   +   + FL  FS+    SF    A +  ++       N P +LVG K DL + 
Sbjct: 305 DRLRPLSYPQTDVFLICFSLISPASFENVKAKWYPEVSH--HCPNTPIILVGTKLDLRED 132

Query: 135 RQVSVEEAKNR 145
           ++ ++E+ K +
Sbjct: 131 KE-TIEKLKEK 102
>19006
          Length = 568

 Score = 75.9 bits (185), Expect = 1e-14,   Method: Compositional matrix adjust.
 Identities = 43/122 (35%), Positives = 65/122 (53%)
 Frame = -2

Query: 10  NSLALHKVIMVGSGGVGKSALTLQFMYDEFVEDYEPTKADSYRKKVVLDGEEVQIDILDT 69
           N     K+++VG G  GK+ L + F  D+F E Y PT  ++Y   + +D ++V++ + DT
Sbjct: 450 NGCHKEKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDSKQVELALWDT 271

Query: 70  AGQEDYAAIRDNYFRSGEGFLCVFSITEMESFAATADFREQILRVKEDENVPFLLVGNKS 129
           AGQEDY  +R   +   +  L  FSI   +S     +     +R     NVP +LVGNK 
Sbjct: 270 AGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVR-HFCPNVPIILVGNKK 94

Query: 130 DL 131
           DL
Sbjct: 93  DL 88
>06994
          Length = 429

 Score = 55.5 bits (132), Expect(2) = 4e-14,   Method: Compositional matrix adjust.
 Identities = 30/91 (32%), Positives = 44/91 (48%), Gaps = 32/91 (35%)
 Frame = +1

Query: 43  YEPTKADSYRKKVVLDGEEVQIDILDTAG------------------------------- 71
           Y+PT  DSYRK+V +DG++  ++ILDTAG                               
Sbjct: 142 YDPTIEDSYRKQVEVDGQQCMLEILDTAGTVHASHSNACVHGSLHAFVGTVTPLGRDALL 321

Query: 72  -QEDYAAIRDNYFRSGEGFLCVFSITEMESF 101
             E + A+RD Y ++G+GFL  +SIT   +F
Sbjct: 322 NTEQFTAMRDLYMKNGQGFLLAYSITAQSTF 414

 Score = 38.9 bits (89), Expect(2) = 4e-14,   Method: Compositional matrix adjust.
 Identities = 17/27 (62%), Positives = 24/27 (88%)
 Frame = +3

Query: 15 HKVIMVGSGGVGKSALTLQFMYDEFVE 41
          +K++++GSGGVGKSALT+QF+   FVE
Sbjct: 57 YKLVVLGSGGVGKSALTVQFVQGIFVE 137
>07465
          Length = 1103

 Score = 73.9 bits (180), Expect = 4e-14,   Method: Compositional matrix adjust.
 Identities = 47/144 (32%), Positives = 80/144 (55%), Gaps = 3/144 (2%)
 Frame = +3

Query: 28  SALTLQFMYDEFVEDYEPT-KADSYRKKVVLDGEEVQIDILDTAGQEDYAAIRDNYFRSG 86
           S++  ++    F +DY+ T   D   +++ + GE+V++ + DTAGQE++ AI   Y+R  
Sbjct: 240 SSMIQRYCKGIFTKDYKKTIGVDFLERQIEVGGEDVRLMLWDTAGQEEFDAITKAYYRGA 419

Query: 87  EGFLCVFSITEMESFAATADFREQILRVKEDE--NVPFLLVGNKSDLEDKRQVSVEEAKN 144
           +  +  FS  + +SF A   ++ ++    EDE   +  ++V NK DL D   V  EEA+N
Sbjct: 420 QACVLAFSTVDRDSFEALETWKRKV----EDEVGEIGMVIVQNKIDLIDDAVVRPEEAEN 587

Query: 145 RADQWNVNYVETSAKTRANVDKVF 168
            A +  + +  TS K   NVD+VF
Sbjct: 588 LAKKLRLRFYRTSVKENMNVDEVF 659
>19656
          Length = 428

 Score = 70.1 bits (170), Expect = 6e-13,   Method: Compositional matrix adjust.
 Identities = 33/86 (38%), Positives = 49/86 (56%)
 Frame = +3

Query: 16  KVIMVGSGGVGKSALTLQFMYDEFVEDYEPTKADSYRKKVVLDGEEVQIDILDTAGQEDY 75
           K ++VG G VGK+ L + +  + F  +Y PT  D+Y   V++DG  V + + DTAGQEDY
Sbjct: 117 KCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGRPVNLGLWDTAGQEDY 296

Query: 76  AAIRDNYFRSGEGFLCVFSITEMESF 101
             +R   +   + FL  FS+    SF
Sbjct: 297 DRLRPLSYPQTDVFLLCFSVASPASF 374
>26083
          Length = 432

 Score = 68.6 bits (166), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 39/120 (32%), Positives = 65/120 (54%), Gaps = 1/120 (0%)
 Frame = +1

Query: 10  NSLALHKVIMVGSGGVGKSALTLQFMYDEFVEDYEPTKA-DSYRKKVVLDGEEVQIDILD 68
           N L   K++ +G   VGK++L  +FMYD F   Y+ T   D   K + L+   +++ + D
Sbjct: 64  NPLRKFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTIRLQLWD 243

Query: 69  TAGQEDYAAIRDNYFRSGEGFLCVFSITEMESFAATADFREQILRVKEDENVPFLLVGNK 128
           TAGQE + ++  +Y R     + V+ IT   SF  T+ + + + R +   +V  +LVGNK
Sbjct: 244 TAGQERFRSLIPSYIRDSSVAVVVYDITNANSFHQTSKWIDDV-RTERGSDVIIMLVGNK 420
>01972
          Length = 2359

 Score = 68.2 bits (165), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 34/115 (29%), Positives = 66/115 (57%)
 Frame = +3

Query: 61  EVQIDILDTAGQEDYAAIRDNYFRSGEGFLCVFSITEMESFAATADFREQILRVKEDENV 120
           +++ ++ DTAGQE +  +RD Y+  G+  + +F +T   ++    ++   ++RV   EN+
Sbjct: 444 KLKFNVWDTAGQEKFGGLRDGYYIQGQCAVIMFDVTSRVTYKNVPNWHRDLVRV--CENI 617

Query: 121 PFLLVGNKSDLEDKRQVSVEEAKNRADQWNVNYVETSAKTRANVDKVFFDLMREI 175
           P +L GNK D++D++  +     +R    N+ Y + SAK+  N +K F  L R++
Sbjct: 618 PIVLCGNKVDIKDRKVKAKAIVFHRKK--NLQYYDISAKSNYNFEKPFLWLARKL 776
>33380
          Length = 282

 Score = 65.5 bits (158), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 34/74 (45%), Positives = 44/74 (59%)
 Frame = +3

Query: 62  VQIDILDTAGQEDYAAIRDNYFRSGEGFLCVFSITEMESFAATADFREQILRVKEDENVP 121
           V++ I DTAGQE Y  I   Y+R   GF+ ++ +T  ESF A  D+  QI     D N  
Sbjct: 60  VKLQIWDTAGQERYRTITTAYYRGAMGFILMYDVTNEESFNAVQDWCTQIKTYSWD-NAQ 236

Query: 122 FLLVGNKSDLEDKR 135
            +LVGNK DLED+R
Sbjct: 237 VVLVGNKCDLEDER 278
>33794
          Length = 779

 Score = 64.7 bits (156), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 36/119 (30%), Positives = 66/119 (55%)
 Frame = -1

Query: 55  VVLDGEEVQIDILDTAGQEDYAAIRDNYFRSGEGFLCVFSITEMESFAATADFREQILRV 114
           ++L+G+ V++ I DT+GQ  +  I  +Y R  +G + V+ IT   SF     + +++   
Sbjct: 671 ILLEGKRVKLQIWDTSGQGRFCTIIRSYSRGAQGIILVYDITNKWSFDGIDRWLKEV--E 498

Query: 115 KEDENVPFLLVGNKSDLEDKRQVSVEEAKNRADQWNVNYVETSAKTRANVDKVFFDLMR 173
           +    +P +LVGN+  L  KRQV+ ++A+  A + N++  E S     N+ + F +L R
Sbjct: 497 EHAPGIPKVLVGNRLHLAYKRQVAAKQAETYASRNNMSCFEISPLCDFNIRESFCELAR 321
>13750
          Length = 503

 Score = 64.7 bits (156), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 39/118 (33%), Positives = 65/118 (55%), Gaps = 4/118 (3%)
 Frame = -2

Query: 58  DGEEVQIDILDTAGQEDYAAIRDNYFRSGEGFLCVFSITEMESF-AATADFREQILRVKE 116
           D   V+  + DT G E Y ++  ++FR  +  L V+ +T   SF  AT  +R+ +++   
Sbjct: 403 DPLNVRYTLWDTGGAETYRSLWVSHFRGAQVALLVYDVTCEWSFLTATTVWRKALMK--- 233

Query: 117 DENVP---FLLVGNKSDLEDKRQVSVEEAKNRADQWNVNYVETSAKTRANVDKVFFDL 171
             N+P    + VG+K+DLE+ R +S E  +  A Q    + ETS+ T  NVD VF+++
Sbjct: 232 --NIPEAQVIFVGSKTDLEENRVISTERGQAFATQCGYTFFETSSVTGKNVDAVFWEI 65
>01398
          Length = 1421

 Score = 63.5 bits (153), Expect = 6e-11,   Method: Compositional matrix adjust.
 Identities = 33/103 (32%), Positives = 58/103 (56%)
 Frame = -2

Query: 72   QEDYAAIRDNYFRSGEGFLCVFSITEMESFAATADFREQILRVKEDENVPFLLVGNKSDL 131
            QE + +I  +Y+R+  G + V+ IT+  +F     + E+     E     FL++G+KSD 
Sbjct: 1420 QERFRSITRSYYRNSVGVIIVYDITKRSTFENLKQWYEEARNHIEPHKAIFLVLGHKSDR 1241

Query: 132  EDKRQVSVEEAKNRADQWNVNYVETSAKTRANVDKVFFDLMRE 174
            ED RQV+  E +  A+   + + ETSAK+  N++ VF  + ++
Sbjct: 1240 EDARQVTAREGRRFAEMHGLKFFETSAKSGHNIEDVFAQIAKD 1112
>05468
          Length = 1558

 Score = 60.5 bits (145), Expect = 5e-10,   Method: Compositional matrix adjust.
 Identities = 38/160 (23%), Positives = 83/160 (51%), Gaps = 7/160 (4%)
 Frame = -3

Query: 14   LHKVIMVGSGGVGKSALTLQFMYDEFVEDYEPTKADSYRKKVV-LDGEE-VQIDILDTAG 71
            L+K++++G  G GK+++  ++++  F + Y  T    +  KV+  D +  +++ + D AG
Sbjct: 1541 LYKILVIGELGTGKTSIIKRYVHQFFSQHYRATIGVDFALKVLNWDADTLIRLQLWDIAG 1362

Query: 72   QEDYAAIRDNYFRSGEGFLCVFSITEMESFAATADFREQI---LRVKEDENVPFLLVGNK 128
            QE +  +   Y++   G   VF +T   +F A   ++  +   +++ +   VP +L+ NK
Sbjct: 1361 QERFGNMTRVYYKEAVGAFVVFDVTRASTFDAVTKWKNDLDSKVQLADGSPVPCVLLANK 1182

Query: 129  SDLEDKRQVSVEEAKNR--ADQWNVNYVETSAKTRANVDK 166
             D   +  V+     +   +++  + + ETSAK   N+D+
Sbjct: 1181 CDQAKEGLVNNTSQMDEFCSEKGFIGWYETSAKENINIDE 1062
>34359
          Length = 1042

 Score = 57.8 bits (138), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 23/74 (31%), Positives = 45/74 (60%)
 Frame = +3

Query: 62  VQIDILDTAGQEDYAAIRDNYFRSGEGFLCVFSITEMESFAATADFREQILRVKEDENVP 121
           ++ ++ DTAGQE +  +RD Y+  G   + +F +T   ++    ++   ++RV   EN+P
Sbjct: 195 LRFNVWDTAGQEKFGGLRDGYYIQGTCAIIMFDVTSRVTYKNVPNWHRDLVRV--CENIP 368

Query: 122 FLLVGNKSDLEDKR 135
            +L GNK D++D++
Sbjct: 369 IVLCGNKVDIKDRK 410
>32723
          Length = 384

 Score = 57.0 bits (136), Expect = 5e-09,   Method: Compositional matrix adjust.
 Identities = 31/107 (28%), Positives = 58/107 (54%)
 Frame = +2

Query: 72  QEDYAAIRDNYFRSGEGFLCVFSITEMESFAATADFREQILRVKEDENVPFLLVGNKSDL 131
           QE + +I  +Y+RS    + V+ +   +S+ +   +  +I  +     V   LVGNK D 
Sbjct: 2   QERFRSITQSYYRSANALILVYDVCSQQSYESLPQWIHEI-ELYAGTKVLAFLVGNKIDQ 178

Query: 132 EDKRQVSVEEAKNRADQWNVNYVETSAKTRANVDKVFFDLMREIRAR 178
            DKR++     K  A+++ + ++ETSAK   NV+K+F  +  ++ A+
Sbjct: 179 TDKREIPTHIGKEFAERYEMRFLETSAKEADNVEKLFSTIAYQLTAQ 319
>01095
          Length = 1745

 Score = 53.5 bits (127), Expect = 7e-08,   Method: Compositional matrix adjust.
 Identities = 28/85 (32%), Positives = 52/85 (61%)
 Frame = -1

Query: 91   CVFSITEMESFAATADFREQILRVKEDENVPFLLVGNKSDLEDKRQVSVEEAKNRADQWN 150
             V+ IT  ++F     + +++ R +   N+   L GNK+DL +KR V  EEA+  A++ +
Sbjct: 1745 VVYDITNQDTFGRAKTWVKELQR-QASPNIVIALAGNKADLANKRMVEFEEAQAYAEENS 1569

Query: 151  VNYVETSAKTRANVDKVFFDLMREI 175
            + ++ETSAKT  NV+ +F  + +++
Sbjct: 1568 LLFMETSAKTAMNVNDIFLAIAKKL 1494
>13745
          Length = 1045

 Score = 52.8 bits (125), Expect = 9e-08,   Method: Compositional matrix adjust.
 Identities = 35/105 (33%), Positives = 56/105 (53%), Gaps = 8/105 (7%)
 Frame = +2

Query: 72  QEDYAAIRDNYFRSGEGFLCVFSITEMESFAATADFREQIL---RVKEDENVPFLLVGNK 128
           QE + ++   ++R  +  + V+ +T   SF     +R++ L     ++ E+ PF+++GNK
Sbjct: 2   QERFQSLGVAFYRGADCCVLVYDVTAPNSFKNLDSWRDEFLIQASPRDPEHFPFVVLGNK 181

Query: 129 SDLEDKRQVSVEEAKNRADQW-----NVNYVETSAKTRANVDKVF 168
            DL D RQVS      RA QW     ++ Y ETSAK   NV+  F
Sbjct: 182 VDL-DNRQVSTR----RAQQWCQSKNDIPYYETSAKEGINVEMAF 301
>13901
          Length = 962

 Score = 49.3 bits (116), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 27/104 (25%), Positives = 55/104 (52%), Gaps = 6/104 (5%)
 Frame = -3

Query: 4   NKPKGQNSL----ALHKVIMVGSGGVGKSALTLQFMYDEFVEDYEPTKADSYRKKVVL-- 57
           +K + QN +     L KVI++G   VGK++   +++ D F  DY+ T    +  KV+   
Sbjct: 330 SKLRTQNLIMSEEVLFKVIIIGDPTVGKTSFVQRYVNDSFRRDYKMTIGVDFALKVIRWS 151

Query: 58  DGEEVQIDILDTAGQEDYAAIRDNYFRSGEGFLCVFSITEMESF 101
           D   +++ + D AGQE + ++   Y++     + +F +T+  ++
Sbjct: 150 DKCNIKLQLWDIAGQERFTSMTRVYYKDAHACIVMFDLTQKNTY 19
>35581
          Length = 364

 Score = 47.4 bits (111), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 26/92 (28%), Positives = 44/92 (47%), Gaps = 2/92 (2%)
 Frame = +2

Query: 4   NKPKGQNSLALHKVIMVGSGGVGKSALTLQFMYDEFVED--YEPTKADSYRKKVVLDGEE 61
           N  +  N     K +++G  GVGK+ L  +   D+F++      T A       +  G  
Sbjct: 14  NGIRTGNDTLYFKCVLLGDAGVGKTCLLNRLATDKFLDSPLTSLTTASLLTTVTLTSGVM 193

Query: 62  VQIDILDTAGQEDYAAIRDNYFRSGEGFLCVF 93
             +D+ DTAGQE Y ++  +Y+R  +  L V+
Sbjct: 194 ASVDLWDTAGQERYRSLTSSYYRDTKAVLIVY 289
>12339
          Length = 578

 Score = 47.4 bits (111), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 28/101 (27%), Positives = 57/101 (56%), Gaps = 4/101 (3%)
 Frame = -2

Query: 72  QEDYAAIRDNYFRSGEGFLCVFSITEMESFAATADFREQILR---VKEDENVPFLLVGNK 128
           QE + ++   ++R  +  + V+ +TE ++F +   ++ + L     ++ E+ PF+++GNK
Sbjct: 577 QERFQSLGVAFYRGADCCILVYDVTEXKTFDSLDSWQREFLNQASPRDPEHFPFVVIGNK 398

Query: 129 SDLEDKRQVSVEEAKNR-ADQWNVNYVETSAKTRANVDKVF 168
            DL D R V+ +  +   + +  + Y ETSAK   NV++ F
Sbjct: 397 IDL-DNRVVTAKRGQGWCSTKGGIPYFETSAKEAINVEQAF 278
>34597
          Length = 773

 Score = 46.6 bits (109), Expect = 8e-06,   Method: Compositional matrix adjust.
 Identities = 22/59 (37%), Positives = 39/59 (66%)
 Frame = -2

Query: 117 DENVPFLLVGNKSDLEDKRQVSVEEAKNRADQWNVNYVETSAKTRANVDKVFFDLMREI 175
           +E+V  +++GNK D+ DKR VS E  +  A + ++ ++ETSAK+  N+++ F +L   I
Sbjct: 661 NEDVEKMILGNKCDMTDKRVVSKERGEAIAREHSIRFMETSAKSNINIERAFCELAEAI 485
>17872
          Length = 700

 Score = 45.8 bits (107), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 34/109 (31%), Positives = 50/109 (45%), Gaps = 12/109 (11%)
 Frame = -1

Query: 72  QEDYAAIRDNYFRSGEGFLCVFSITEMESFAATADFREQILRVKEDENVPFLLVGNKSDL 131
           Q+D+ ++R   +     FL  FS+    SF    +     LR       P ++VG +SDL
Sbjct: 700 QDDFDSLRPLCYPETNVFLLCFSVVSPTSFHNVMEKWVPELRY-HCPGAPLVVVGTQSDL 524

Query: 132 ED------------KRQVSVEEAKNRADQWNVNYVETSAKTRANVDKVF 168
            +            ++ VS EEA   ADQ    YVE SA T+ N+ +VF
Sbjct: 523 RNDVKVLIELAKYKEKPVSEEEAVKMADQLGAQYVECSALTQKNLKEVF 377
>31291
          Length = 446

 Score = 44.7 bits (104), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 34/124 (27%), Positives = 56/124 (45%), Gaps = 14/124 (11%)
 Frame = -1

Query: 64  IDILDTAGQEDYAAIRDNYFRSGEGFLCVFSITEMESFA-ATADFREQILRVKEDENVPF 122
           + + DTAGQEDY  +R   + + + F+  FS+    S       +  +I     D +VP 
Sbjct: 446 LQLWDTAGQEDYDRLRPLAYPNTDVFMLXFSLMSEASMKNVKVKWYPEIRH--HDPHVPI 273

Query: 123 LLVGNKSDLEDKRQVSVEEAKNRADQWNVN-------------YVETSAKTRANVDKVFF 169
           +LVG K DL   ++   +   +R D  + N             Y E S+KT+ N+   F 
Sbjct: 272 VLVGTKLDLRQDKEAVRKLRSSRQDPVSSNQGNDLAKAIKAKRYFECSSKTQENLKTAFE 93

Query: 170 DLMR 173
           + +R
Sbjct: 92  ETVR 81
>00552
          Length = 455

 Score = 37.4 bits (85), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 19/48 (39%), Positives = 31/48 (64%), Gaps = 1/48 (2%)
 Frame = -1

Query: 14  LHKVIMVGSGGVGKSALTLQFMYDEF-VEDYEPTKADSYRKKVVLDGE 60
           L KV+++G GGVGKS+L  +F+ ++F  + +     +   K VV+DGE
Sbjct: 446 LLKVVLLGDGGVGKSSLMNRFVSNKFDAQSFHTIGVEFLTKDVVVDGE 303

 Score = 37.0 bits (84), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 15/47 (31%), Positives = 29/47 (61%)
 Frame = -3

Query: 66  ILDTAGQEDYAAIRDNYFRSGEGFLCVFSITEMESFAATADFREQIL 112
           I DTAGQE Y ++R  ++R  +  L  FS+  ++S  + +D+ ++ +
Sbjct: 147 IWDTAGQERYKSLRTPFYRGTDCCLLTFSVDNLKSLQSLSDWYDEFV 7
>10708
          Length = 2775

 Score = 35.8 bits (81), Expect = 0.011,   Method: Compositional matrix adjust.
 Identities = 31/102 (30%), Positives = 53/102 (51%), Gaps = 23/102 (22%)
 Frame = -3

Query: 90   LCVFSITEMESFAATA-----DFREQILRVKED-----ENVPFLLVGNKSDLED----KR 135
            LC+ ++T+M S  A+       +R  + +   +      NVP +LVGNK DL +    KR
Sbjct: 2668 LCL-TLTQMSSLCASPLTALTAWRTSLKKWTPEVRHFCPNVPIILVGNKKDLRNDENTKR 2492

Query: 136  Q--------VSVEEAKNRADQWNV-NYVETSAKTRANVDKVF 168
            +        V ++E +  +++ N  +Y+E SAKT+  V +VF
Sbjct: 2491 ELMKMKQEPVRLDEGRAMSEKINAYSYLECSAKTKEGVREVF 2366

 Score = 32.3 bits (72), Expect = 0.15,   Method: Compositional matrix adjust.
 Identities = 20/64 (31%), Positives = 30/64 (46%)
 Frame = -2

Query: 60   EEVQIDILDTAGQEDYAAIRDNYFRSGEGFLCVFSITEMESFAATADFREQILRVKEDEN 119
            ++V++ + DTAGQEDY  +R   +   +  L  FSI   +S        E I    +   
Sbjct: 2729 QQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSL-------ENIPEKVDSRG 2571

Query: 120  VPFL 123
             PFL
Sbjct: 2570 APFL 2559
>09700
          Length = 1855

 Score = 34.3 bits (77), Expect = 0.038,   Method: Compositional matrix adjust.
 Identities = 21/61 (34%), Positives = 32/61 (52%), Gaps = 12/61 (19%)
 Frame = -1

Query: 120  VPFLLVGNKSDLEDKRQVSVEEAKNR------------ADQWNVNYVETSAKTRANVDKV 167
             P +LVG +SDL +  +V +E AK +            A Q   +YVE SA T+ N+ ++
Sbjct: 1816 TPLVLVGTQSDLRNDVKVLIELAKYKEKPVSEDDASKLAHQLGASYVECSALTQKNLKEM 1637

Query: 168  F 168
            F
Sbjct: 1636 F 1634
>31932
          Length = 437

 Score = 33.1 bits (74), Expect = 0.092,   Method: Compositional matrix adjust.
 Identities = 21/60 (35%), Positives = 35/60 (58%), Gaps = 1/60 (1%)
 Frame = -1

Query: 120 VPFLLVGNKSDLEDKRQVSVEEAKNRADQWN-VNYVETSAKTRANVDKVFFDLMREIRAR 178
           VP LL+GNKSDL   R+V  +E ++   + + + + ETS K    +D+    L+ E+ A+
Sbjct: 401 VPCLLLGNKSDL-GHREVEQDEIEDLCKEHDFLGWSETSVKDGTMIDESMNYLIEEMMAK 225
>09827
          Length = 1201

 Score = 32.7 bits (73), Expect = 0.11,   Method: Compositional matrix adjust.
 Identities = 34/158 (21%), Positives = 69/158 (43%), Gaps = 10/158 (6%)
 Frame = -3

Query: 16   KVIMVGSGGVGKSALTLQFMYDEFVEDYEPTKADSYRKKVVLDGEEVQIDILDTAGQEDY 75
            +++MVG    GK+ +  +    E V    PT   +      ++ + +   + D  GQ+  
Sbjct: 1109 RILMVGLDAAGKTTILYKLKLGEIVTTI-PTIGFNVE---TVEYKNISFTVWDVGGQDKI 942

Query: 76   AAIRDNYFRSGEGFLCVFSITEMESFAATADFREQILR-VKEDE--NVPFLLVGNKSDL- 131
              +  +YF++ +G + V    + E      + RE++ R + EDE  +   L+  NK DL 
Sbjct: 941  RPLWRHYFQNTQGLIFVVDSNDKER---VQEAREELTRMLNEDELRDAVLLVFANKQDLP 771

Query: 132  ------EDKRQVSVEEAKNRADQWNVNYVETSAKTRAN 163
                  E   ++ +   +NR   W   Y++++  T  +
Sbjct: 770  HAMATAEITEKLGLHGLRNRT--W---YIQSTCATTGD 672
>11378
          Length = 1688

 Score = 32.0 bits (71), Expect = 0.20,   Method: Compositional matrix adjust.
 Identities = 23/115 (20%), Positives = 53/115 (46%)
 Frame = +3

Query: 16  KVIMVGSGGVGKSALTLQFMYDEFVEDYEPTKADSYRKKVVLDGEEVQIDILDTAGQEDY 75
           K++ +G    GK+ L L  + D+ +  + PT   +  +++ + G  ++    D  G    
Sbjct: 327 KLVFLGLDNAGKTTL-LHMLKDDKMAQHVPTLHPT-SEELSMGG--MRFTTFDLGGHRQA 494

Query: 76  AAIRDNYFRSGEGFLCVFSITEMESFAATADFREQILRVKEDENVPFLLVGNKSD 130
             +  +YF + +G + +  + + E         + ++  ++  N P L++GNK D
Sbjct: 495 RRVWKDYFPAVDGIVFLVDVHDRERLVEAKAELDSLMTDEQVANAPILVLGNKID 659
>32770
          Length = 387

 Score = 31.2 bits (69), Expect = 0.32,   Method: Compositional matrix adjust.
 Identities = 18/58 (31%), Positives = 27/58 (46%), Gaps = 7/58 (12%)
 Frame = +2

Query: 118 ENVPFLLVGNKSDLEDKRQ------VSVEEAKNRADQWN-VNYVETSAKTRANVDKVF 168
              PF+LVG ++DL    Q      V   + K  A +   + Y E SA   + +D+VF
Sbjct: 23  PGTPFILVGTQADLRHHSQPASKDMVPAHKGKKLARKVGALGYFECSALIGSGLDRVF 196
>08153
          Length = 1703

 Score = 31.2 bits (69), Expect = 0.34,   Method: Compositional matrix adjust.
 Identities = 24/123 (19%), Positives = 51/123 (41%)
 Frame = +1

Query: 16  KVIMVGSGGVGKSALTLQFMYDEFVEDYEPTKADSYRKKVVLDGEEVQIDILDTAGQEDY 75
           +++MVG    GK+ +  +    E V    PT   +      ++ + +   + D  GQ+  
Sbjct: 88  RILMVGLDAAGKTTILYKLKLGEIVTTI-PTIGFNVE---TVEYKNISFTVWDVGGQDKI 255

Query: 76  AAIRDNYFRSGEGFLCVFSITEMESFAATADFREQILRVKEDENVPFLLVGNKSDLEDKR 135
             +  +YF++ +G + V    + E      +   ++L   +  +   L+  NK DL +  
Sbjct: 256 RPLWRHYFQNTQGLIFVVDSNDRERINEAKEELARMLNEDDLRDAIILVFANKQDLPNAY 435

Query: 136 QVS 138
             S
Sbjct: 436 SAS 444
>31928
          Length = 429

 Score = 30.8 bits (68), Expect = 0.44,   Method: Compositional matrix adjust.
 Identities = 19/78 (24%), Positives = 36/78 (46%), Gaps = 6/78 (7%)
 Frame = +2

Query: 81  NYFRSGEGFLCVFSITEMESFAATADFREQILRVKEDENVPFLLVGNKSDLEDKRQVSV- 139
           +Y    +GF+ V+  T  ESF      ++ I + ++   V  +++GNK   + +   SV 
Sbjct: 170 HYLNFPDGFVLVYDTTSWESFRRLDKLKKDIDKHRDKREVHMIVIGNKE*DDGETPSSV* 349

Query: 140 -----EEAKNRADQWNVN 152
                  AK +   W+V+
Sbjct: 350 QLPRAGPAKRKLRHWDVS 403
>33605
          Length = 888

 Score = 30.4 bits (67), Expect = 0.59,   Method: Compositional matrix adjust.
 Identities = 18/77 (23%), Positives = 38/77 (49%)
 Frame = +1

Query: 16  KVIMVGSGGVGKSALTLQFMYDEFVEDYEPTKADSYRKKVVLDGEEVQIDILDTAGQEDY 75
           +++M+G    GK+ +  +F   E ++   PT   + +    L+    ++++ D  GQ+  
Sbjct: 502 RLLMLGLDNAGKTTILKKF-NGEDIDTISPTLGFNIK---TLEHRGFKLNVWDVGGQQSL 669

Query: 76  AAIRDNYFRSGEGFLCV 92
            +   NYF S +G + V
Sbjct: 670 RSYWRNYFESTDGLVWV 720
>31774
          Length = 373

 Score = 28.1 bits (61), Expect = 2.3,   Method: Compositional matrix adjust.
 Identities = 14/31 (45%), Positives = 20/31 (64%)
 Frame = +3

Query: 13 ALHKVIMVGSGGVGKSALTLQFMYDEFVEDY 43
          A  +V ++G+  VGKSAL  QFM  E++  Y
Sbjct: 69 AYFRVAVMGTVEVGKSALCRQFMSSEYLGTY 161
>14775
          Length = 380

 Score = 27.7 bits (60), Expect = 3.4,   Method: Compositional matrix adjust.
 Identities = 13/35 (37%), Positives = 20/35 (57%)
 Frame = -2

Query: 137 VSVEEAKNRADQWNVNYVETSAKTRANVDKVFFDL 171
           V+ E  +  A Q    + ETS+ T  NVD VF+++
Sbjct: 169 VTCERGQAFATQCGYTFFETSSVTGKNVDAVFWEI 65
>22274
          Length = 1235

 Score = 26.9 bits (58), Expect = 5.4,   Method: Compositional matrix adjust.
 Identities = 10/24 (41%), Positives = 15/24 (62%)
 Frame = +1

Query: 87  EGFLCVFSITEMESFAATADFREQ 110
           +G   +FSI  + +F   ADFR+Q
Sbjct: 925 QGLNMIFSICNLSAFTVNADFRQQ 996
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|27370440|ref|NP_766520.1| neuroligin 3 [Mus musculus]
         (825 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

17447                                                                 159   1e-40
07330                                                                  95   1e-19
05383                                                                  52   2e-15
20212                                                                  54   3e-07
12073                                                                  52   8e-07
01645                                                                  51   2e-06
29534                                                                  46   5e-05
35653                                                                  34   0.23 
12297                                                                  34   0.31 
37200                                                                  33   0.43 
26582                                                                  31   2.0  
>17447
          Length = 783

 Score =  159 bits (401), Expect(2) = 1e-40,   Method: Compositional matrix adjust.
 Identities = 81/171 (47%), Positives = 115/171 (67%), Gaps = 5/171 (2%)
 Frame = -3

Query: 178 PVMVYIHGGSYMEGTGNMIDGSVLASYGNVIVITLNYRVGVLGFLSTGDQAAKGNYGLLD 237
           PVMV+IHGG Y+ GTG+ +D SVLA  G V+ +++NYR+  LGFLST D  + GNYG+ D
Sbjct: 697 PVMVWIHGGGYVIGTGSDVDMSVLAMKG-VVGVSINYRLAALGFLSTEDAVSPGNYGMYD 521

Query: 238 QIQALRWVSENIAFFGGDPRRITVFGSGIGASCVSLLTLSHHSEGLFQRAIIQSGSALSS 297
           QI+AL W+ + I+ F GDP  +T+FG   GAS V LL LS  ++GLF +AI+QSGS+L+ 
Sbjct: 520 QIRALEWIRDTISSFNGDPNDVTIFGESAGASSVDLLFLSPKAKGLFHKAIMQSGSSLNQ 341

Query: 298 WAVNY-----QPVKYTSLLADKVGCNVLDTVDMVDCLRQKSAKELVEQDIQ 343
           +++        PV     LA ++ C+V ++V M+DCLR KS + +V    Q
Sbjct: 340 FSLALPRRDPDPVSTARALASRLSCDVTNSVAMLDCLRSKSLESIVSATRQ 188

 Score = 26.9 bits (58), Expect(2) = 1e-40,   Method: Compositional matrix adjust.
 Identities = 10/12 (83%), Positives = 11/12 (91%)
 Frame = -1

Query: 135 NEDCLYLNVYVP 146
           +EDCLYLNVY P
Sbjct: 762 SEDCLYLNVYTP 727
>07330
          Length = 746

 Score = 94.7 bits (234), Expect = 1e-19,   Method: Compositional matrix adjust.
 Identities = 67/223 (30%), Positives = 96/223 (43%), Gaps = 31/223 (13%)
 Frame = +1

Query: 70  PYAAPPIGEKRFLPPEPPPSWSGIRNATHFPPVCPQNIHTAVPEVMLPVWFTANLDIVAT 129
           P  + P+G +RF  P+P  +    R  T      P     A     +P   T        
Sbjct: 16  PTLSRPLGSRRFAKPQPTQAQDKARCLTP-----PARAARASKNSWIPGLPT-------- 156

Query: 130 YIQEPNEDCLYLNVYVPT--------EDGSGAKK-----------------------QXX 158
                NEDCL L+VYVPT         + +G  K                       Q  
Sbjct: 157 -----NEDCLTLSVYVPTPASDKCQLRNDTGPCKAFFQNYYYDSTVGQCRQFVYGGCQGN 321

Query: 159 XXXXXXXXXXXXXXXXXAKPVMVYIHGGSYMEGTGNMIDGSVLASYGNVIVITLNYRVGV 218
                            +KPVM++IHGG +  G+      SVL +  +VIV+ + YR+  
Sbjct: 322 ENNFLTLEDCQKACPSRSKPVMIWIHGGGFTLGSALDYTPSVLVTSRDVIVVVIQYRLDA 501

Query: 219 LGFLSTGDQAAKGNYGLLDQIQALRWVSENIAFFGGDPRRITV 261
           LGFLS+GD  + GNY + DQ+ A++WV +NI  FGGDP+ I++
Sbjct: 502 LGFLSSGDDVSPGNYAMWDQVMAVQWVKDNIQAFGGDPQSISL 630
>05383
          Length = 1210

 Score = 51.6 bits (122), Expect(2) = 2e-15,   Method: Compositional matrix adjust.
 Identities = 58/245 (23%), Positives = 100/245 (40%), Gaps = 12/245 (4%)
 Frame = +1

Query: 267 GASCVSLLTLSHHSEGLFQRAIIQSGSALSSWAVNYQPVKYTSLLADKVGCNVLDTVDMV 326
           G + VS+ T S    G++  A +Q+ +                 LA  + C++ D+  M+
Sbjct: 55  GGAGVSMTTWSSAHRGVWPEARVQART-----------------LAKGLHCDMSDSPAML 183

Query: 327 DCLRQKSAKELV--EQDIQPARYHVAFXXXXXXX-----XXXXXXEILMEQGEFLNYDIM 379
            CLR K A  +V    +++ A   + F                    L+EQG F +   M
Sbjct: 184 ACLRTKDAMAIVNVSTEMEKAAGDILFRPVIEETFGQPGLFSGTVRDLLEQGLFNSVTAM 363

Query: 380 LGVNQGEGLKFVEGVVDPE-DGVSGTDFDYSVSNFVD---NLYGYPEGKDTLRETIKFMY 435
            G N+ E       V DP+ DG++ ++F  S+ + V    + Y     +DT    ++  Y
Sbjct: 364 RGYNKYES----SSVSDPDNDGITVSEFKSSLHDLVSWYVSRYSRLSAQDTEAALLE-AY 528

Query: 436 TDWADRDNPETRRKTLVALFTDHQWVEPSVVTADLH-ARYGSPTYFYAFYHHCQSLMKPA 494
               +  +P   R+  + L TD+ ++ P+V    L  A    P Y Y F +   +   P 
Sbjct: 529 ITAPNVTDPVDIRQAAMQLRTDYSFIAPTVEEMKLTVANNPHPQYLYQFSYRSSNRQSPQ 708

Query: 495 WSDAA 499
           W  A+
Sbjct: 709 WQGAS 723

 Score = 49.3 bits (116), Expect(2) = 2e-15,   Method: Compositional matrix adjust.
 Identities = 33/108 (30%), Positives = 51/108 (47%), Gaps = 2/108 (1%)
 Frame = +3

Query: 500 HGDEVPYVFGVPMVGP--TDLFPCNFSKNDVMLSAVVMTYWTNFAKTGDPNKPVPQDTKF 557
           H DE+ YVFG P++     + F  +++ +D  +S  VMT WTNFAK G+P    P  +  
Sbjct: 723 HADELHYVFGSPVIDDFMWNGFATSWTDDDKRVSDDVMTLWTNFAKYGNPT---PSGSN- 890

Query: 558 IHTKANRFEEVAWSKYNPRDQLYLHIGLKPRVRDHYRATKVAFWKHLV 605
                     V W  + P    Y+ IG+  R     RA +++ W   +
Sbjct: 891 ----------VTWLPWTPTSPNYMDIGVTDRPMSGLRAKQMSVWMDTI 1004
>20212
          Length = 587

 Score = 53.5 bits (127), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 38/135 (28%), Positives = 62/135 (45%), Gaps = 12/135 (8%)
 Frame = +2

Query: 448 RKTLVALFTDHQWVEPSVVTADL-HARYGSPTYFYAFYHHCQSLMKPAWSDAAHGDEVPY 506
           RK  + L TD   V P +    + +  +  P Y Y F     + M PA+     G +V Y
Sbjct: 5   RKAYIRLRTDQFMVAPVLQETQMTYQAHAKPQYLYHFSFRSANRMVPAFQGHRTGMDVFY 184

Query: 507 VFGVPMVGPTDL--FPCNFSKNDVMLSAVVMTYWTNFAKTGDPN---------KPVPQDT 555
           + G+P++  T L  F  +++ +D  ++  + T WTNFAK G+P           P  Q T
Sbjct: 185 MLGLPVMNITYLYNFVSSYTDDDRRVANDITTMWTNFAKYGNPTPEGYSGTKWLPWEQAT 364

Query: 556 KFIHTKANRFEEVAW 570
             +     +F+ +AW
Sbjct: 365 PRLLDIGQQFQMLAW 409
>12073
          Length = 1602

 Score = 52.4 bits (124), Expect = 8e-07,   Method: Compositional matrix adjust.
 Identities = 34/129 (26%), Positives = 59/129 (45%), Gaps = 2/129 (1%)
 Frame = +1

Query: 423 GKDTLRETIKFMYTDWADRDNPETRRKTLVALFTDHQWVEPSVVTADLHARYGS--PTYF 480
           G ++  + I + Y D    ++ ++ R     +  D  ++ P+V  A   +   S    Y 
Sbjct: 127 GTESSDKAIMYEYVDSVLPNDRQSYRDIADDIMGDEMFICPTVDFAKAFSSXLSNRSVYL 306

Query: 481 YAFYHHCQSLMKPAWSDAAHGDEVPYVFGVPMVGPTDLFPCNFSKNDVMLSAVVMTYWTN 540
           Y++ H   +   P W+   HG E+  VF +P+         N++  D  L   + TYWT+
Sbjct: 307 YSYEHXLSNYPWPQWTGVMHGYEIEAVFALPL-------DFNYTHTDQTLVNRLTTYWTH 465

Query: 541 FAKTGDPNK 549
           FAK G+PN 
Sbjct: 466 FAKHGNPNN 492
>01645
          Length = 1116

 Score = 51.2 bits (121), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 34/114 (29%), Positives = 49/114 (42%), Gaps = 7/114 (6%)
 Frame = -1

Query: 442 DNPETRRKTLVALFTDHQWVEPSVVTADLHARYGSPTYFYAFYHHCQSLMKPAWS----- 496
           +NP   R+ +V + TD  +  P    + +    G    +   + H  S   P W      
Sbjct: 849 NNPSDEREEMVKMSTDLVFACPIRNASRIMRNLGLKNIWVYIWDHAMSF--PGWGPVTFC 676

Query: 497 --DAAHGDEVPYVFGVPMVGPTDLFPCNFSKNDVMLSAVVMTYWTNFAKTGDPN 548
                HG E+ YVF     G        F+  +  LS+ +M +WTNFAKTGDPN
Sbjct: 675 EGRVCHGSELVYVFHTEWAGN-----FTFTAAEEALSSQIMDFWTNFAKTGDPN 529
>29534
          Length = 416

 Score = 46.2 bits (108), Expect = 5e-05,   Method: Composition-based stats.
 Identities = 36/87 (41%), Positives = 45/87 (51%), Gaps = 3/87 (3%)
 Frame = +2

Query: 254 GDPRRITVFGSGIGASCVSLLTLSHHSEGLFQRAIIQSGSALSSWAVNYQPVKYTSL--- 310
           G    IT+FG   GA+ V    +S  S   F RAI+QS S LS +AV  Q  K TS    
Sbjct: 2   GQQDSITIFGESAGAASVGFHLMSPLSMDHFTRAIMQSWSPLSDYAVMSQ-TKATSRAIK 178

Query: 311 LADKVGCNVLDTVDMVDCLRQKSAKEL 337
           LA  +GC+       V CLRQ SA+ +
Sbjct: 179 LAVILGCDHDSVPSRVHCLRQVSAENV 259
>35653
          Length = 381

 Score = 34.3 bits (77), Expect = 0.23,   Method: Composition-based stats.
 Identities = 28/111 (25%), Positives = 49/111 (44%), Gaps = 4/111 (3%)
 Frame = +2

Query: 498 AAHGDEVPYVFGVPMVGPTDLFPCNFSKNDVMLSAVVMTYWTNFAKTGDPN---KPVPQD 554
           A+H DE+ Y+F        D  P   S  D  +S  +   W NFAK G P+    PV + 
Sbjct: 62  ASHADELSYLFQXI----DDESP--LSAEDAQVSVRLCQMWANFAKHGKPSDTWSPVLRQ 223

Query: 555 TKFIHTKANRFEEVAWSKYNPRDQL-YLHIGLKPRVRDHYRATKVAFWKHL 604
            + ++ +   F            QL Y+ I  + +++ +  A ++ FW+ +
Sbjct: 224 IRNLNGELEPF------------QLDYMQIDWESKMKRNPDAERIDFWRSM 340
>12297
          Length = 808

 Score = 33.9 bits (76), Expect = 0.31,   Method: Compositional matrix adjust.
 Identities = 25/89 (28%), Positives = 35/89 (39%), Gaps = 1/89 (1%)
 Frame = +2

Query: 523 FSKNDVMLSAVVMTYWTNFAKTGDPNKPVP-QDTKFIHTKANRFEEVAWSKYNPRDQLYL 581
           F+ +D  L+       + FA  G P   +P QD               W +Y    Q YL
Sbjct: 191 FNADDFTLATTFKRMLSTFAVHGVPRLDIPPQDAG------------VWPEYTMNQQQYL 334

Query: 582 HIGLKPRVRDHYRATKVAFWKHLVPHLYN 610
            +   PRV  +    +VA W  L+P L N
Sbjct: 335 SLEPVPRVDSYLYGKRVALWLDLLPSLVN 421
>37200
          Length = 291

 Score = 33.1 bits (74), Expect = 0.43,   Method: Composition-based stats.
 Identities = 13/21 (61%), Positives = 16/21 (76%)
 Frame = -1

Query: 66 YLGVPYAAPPIGEKRFLPPEP 86
          YL +PYA PP+GE RF  P+P
Sbjct: 66 YLAIPYAQPPLGELRFEKPQP 4
>26582
          Length = 548

 Score = 31.2 bits (69), Expect = 2.0,   Method: Composition-based stats.
 Identities = 30/103 (29%), Positives = 48/103 (46%), Gaps = 1/103 (0%)
 Frame = +3

Query: 176 AKPVMVYIHGGSYMEGTGNMIDGSVLASYGNVIVITLNYRVGVLGFL-STGDQAAKGNYG 234
           AK + +Y+HG S   G  + +      S  +  V+ ++YR    GF  STG  + +G   
Sbjct: 36  AKHIFLYLHGNSGHRGAYHRVQMYKFMSRLDAHVVAVDYR----GFADSTGSPSEEGV-- 197

Query: 235 LLDQIQALRWVSENIAFFGGDPRRITVFGSGIGASCVSLLTLS 277
           + D     +W+ E     GG P  I V+G  +G    ++LT S
Sbjct: 198 VRDAHFTYKWLKEK---SGGXP--IVVWGHSLGTGISTILTKS 311
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|29293803|ref|NP_038857.1| phospholipase C beta 4 [Mus
musculus]
         (1175 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

01494                                                                 165   1e-40
12795                                                                 138   1e-32
14539                                                                  66   7e-11
19949                                                                  34   0.30 
31669                                                                  30   4.9  
>01494
          Length = 2122

 Score =  165 bits (417), Expect = 1e-40,   Method: Compositional matrix adjust.
 Identities = 90/220 (40%), Positives = 138/220 (62%), Gaps = 9/220 (4%)
 Frame = +1

Query: 611  FVNYNKRQMSRIYPKGGRVDSSNYMPQIFWNAGCQMVSLNYQTPDLAMQLNQGKFEYNGS 670
            F+ Y++ Q+SR+YPKG RVDSSNY P  FWN G QM++LNYQTPD  MQ NQG+F  NG 
Sbjct: 889  FLKYHRTQLSRVYPKGQRVDSSNYDPVPFWNCGSQMLALNYQTPDRLMQFNQGRFLANGR 1068

Query: 671  CGYLLKPDFMRRPDRTFDPFSETPVD--GVIAATCSVQVISGQFL--SDKKIGT-YVEVD 725
            CGY+LKP  M      F P+ +  +   GV   T ++ ++  + L  S + I + +VE++
Sbjct: 1069 CGYILKPAIMNH--DAFSPYEKKFLSQLGVEPLTLTLTIVGARHLVKSGRGIASPFVEIE 1242

Query: 726  MYGLPTDTIRKEFRTRMVMNNGLNPVYNEESFVFRKVILPDLAVLRIAVYDD----NNKL 781
            + G   D   ++F+T   ++NGLNPV+NE   VF  V+ P++A+LR AV D+    +   
Sbjct: 1243 VTGXECDN--QKFKTGTRVDNGLNPVWNENC-VF-DVLCPEMALLRFAVMDEDIFGDPNF 1410

Query: 782  IGQRILPLDGLQAGYRHISLRNEGNKPLSLPTIFCNIVLK 821
            +GQ   P+  ++ GYR +SL+N  ++PL L ++  +I ++
Sbjct: 1411 LGQAXFPVPCIRPGYRSVSLKNGYSEPLELASLLVHIDMR 1530
>12795
          Length = 737

 Score =  138 bits (348), Expect = 1e-32,   Method: Compositional matrix adjust.
 Identities = 82/208 (39%), Positives = 122/208 (58%), Gaps = 6/208 (2%)
 Frame = -3

Query: 553 KYVGATTNIHPYLSTMINYAQPVKFQGFHVAEERNIHYNMSSFNESVGLGYL-KTHAIEF 611
           K +  T  I    S +I Y Q V F    ++      Y MSSF E+    Y+ K  A  F
Sbjct: 693 KMLERTMRIAREFSDLIVYCQAVPFNADRISGP---FYEMSSFPETKAEKYVNKNKAKLF 523

Query: 612 VNYNKRQMSRIYPKGGRVDSSNYMPQIFWNAGCQMVSLNYQTPDLAMQLNQGKFEYNGSC 671
           + Y+  Q+SR+YPKG RVDSSNY P   WN G Q+++LNYQTPD +MQLNQG+F  NG C
Sbjct: 522 LKYHHNQLSRVYPKGQRVDSSNYNPVPMWNCGSQLLALNYQTPDRSMQLNQGRFLANGRC 343

Query: 672 GYLLKPDFMRRPDRTFDPFSETPVD--GVIAATCSVQVISGQFL--SDKKIGT-YVEVDM 726
           GYLL+PD M      FDP+ +  +   GV   T ++ +++ + L  S + I + ++E+++
Sbjct: 342 GYLLRPDIMF--SELFDPYEKKFLSQLGVEPLTLTITLLAARHLVKSGRGIASPFLEIEI 169

Query: 727 YGLPTDTIRKEFRTRMVMNNGLNPVYNE 754
            G+  D   ++FR +  +  G+NPV+N+
Sbjct: 168 AGIECDN--QKFRQKHELTMGVNPVWNK 91
>14539
          Length = 436

 Score = 66.2 bits (160), Expect = 7e-11,   Method: Composition-based stats.
 Identities = 35/105 (33%), Positives = 66/105 (62%), Gaps = 4/105 (3%)
 Frame = +3

Query: 721 YVEVDMYGLPTDTIRKEFRTRMVMNNGLNPVYNEESFVFRKVILPDLAVLRIAVYDDNN- 779
           ++E+++ G+  D   ++F+T   ++NGLNPV+N+   VF  V+ P+LA+LR AV D++  
Sbjct: 87  FLEIEIAGIECDN--QKFKTETRVDNGLNPVWNKNC-VF-DVLCPELALLRFAVMDEDTF 254

Query: 780 ---KLIGQRILPLDGLQAGYRHISLRNEGNKPLSLPTIFCNIVLK 821
                +GQ   P+  +++G+R + L+N   +PL L ++  +I L+
Sbjct: 255 GDPNFLGQGCFPVPCIKSGFRSVPLKNGHGEPLELASLLVHIDLR 389
>19949
          Length = 903

 Score = 34.3 bits (77), Expect = 0.30,   Method: Compositional matrix adjust.
 Identities = 27/86 (31%), Positives = 38/86 (44%), Gaps = 1/86 (1%)
 Frame = +2

Query: 262 FYDAKRAMQIIEMYEPDEELKKKGLISSDGFCRYLMSDENAPVF-LDRLELYQEMDHPLA 320
           F+D +   Q+I   EP+    +  L   DG C Y  S +   V+  + LELY  +  P  
Sbjct: 323 FWDLE-TFQLISTTEPEANSIRSILFHPDGVCLYSGSKDTLKVYHWEPLELYDTVSVPWG 499

Query: 321 HYFISSSHNTYLTGRQFGGKSSVEMY 346
                S  NT L G  F  K++V  Y
Sbjct: 500 QVCDMSISNTQLIGASF-YKTNVASY 574
>31669
          Length = 1032

 Score = 30.4 bits (67), Expect = 4.9,   Method: Composition-based stats.
 Identities = 14/51 (27%), Positives = 26/51 (50%), Gaps = 2/51 (3%)
 Frame = -2

Query: 354 CRCVELDCWDGKGED--QEPIITHGKAMCTDILFKDVIQAIKETAFVTSEY 402
           CRC+++ C    G+D  +  +  HG  +   ILF ++     E+ F+T  +
Sbjct: 491 CRCLKIVCISRHGDDRTKRKMFGHGMKIVRFILFSNINVNTNESIFLTKNF 339
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|56699425|ref|NP_942562.2| neuroligin 2 [Mus musculus]
         (836 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

17447                                                                 157   1e-40
07330                                                                  95   1e-19
05383                                                                  54   7e-16
12073                                                                  60   3e-09
29534                                                                  52   1e-06
20212                                                                  49   1e-05
01645                                                                  45   1e-04
12297                                                                  39   0.008
35653                                                                  36   0.058
37200                                                                  31   2.5  
28623                                                                  30   4.9  
06426                                                                  29   6.9  
>17447
          Length = 783

 Score =  157 bits (398), Expect(2) = 1e-40,   Method: Compositional matrix adjust.
 Identities = 80/168 (47%), Positives = 113/168 (67%), Gaps = 5/168 (2%)
 Frame = -3

Query: 176 KKPVMLFLHGGSYMEGTGNMFDGSVLAAYGNVIVVTLNYRLGVLGFLSTGDQAAKGNYGL 235
           + PVM+++HGG Y+ GTG+  D SVLA  G V+ V++NYRL  LGFLST D  + GNYG+
Sbjct: 703 RLPVMVWIHGGGYVIGTGSDVDMSVLAMKG-VVGVSINYRLAALGFLSTEDAVSPGNYGM 527

Query: 236 LDQIQALRWLSENIAHFGGDPERITIFGSGAGASCVNLLILSHHSEGLFQKAIAQSGTAI 295
            DQI+AL W+ + I+ F GDP  +TIFG  AGAS V+LL LS  ++GLF KAI QSG+++
Sbjct: 526 YDQIRALEWIRDTISSFNGDPNDVTIFGESAGASSVDLLFLSPKAKGLFHKAIMQSGSSL 347

Query: 296 SSWSVNY-----QPLKYTRLLAAKVGCDREDSTEAVECLRRKSSRELV 338
           + +S+        P+   R LA+++ CD  +S   ++CLR KS   +V
Sbjct: 346 NQFSLALPRRDPDPVSTARALASRLSCDVTNSVAMLDCLRSKSLESIV 203

 Score = 28.1 bits (61), Expect(2) = 1e-40,   Method: Composition-based stats.
 Identities = 10/12 (83%), Positives = 11/12 (91%)
 Frame = -1

Query: 138 SEDCLYLNLYVP 149
           SEDCLYLN+Y P
Sbjct: 762 SEDCLYLNVYTP 727
>07330
          Length = 746

 Score = 94.7 bits (234), Expect = 1e-19,   Method: Compositional matrix adjust.
 Identities = 68/223 (30%), Positives = 100/223 (44%), Gaps = 34/223 (15%)
 Frame = +1

Query: 73  PYATPPLGARRFQPPEAPASWPGVRNATTLPPACPQNLHGALPAIMLPVWFTDNLEAAAT 132
           P  + PLG+RRF  P+   +    R  T    A   + +  +P   LP            
Sbjct: 16  PTLSRPLGSRRFAKPQPTQAQDKARCLTPPARAARASKNSWIPG--LPT----------- 156

Query: 133 YVQNQSEDCLYLNLYVPT----------EDGPL-----------------------TKKR 159
                +EDCL L++YVPT          + GP                         +  
Sbjct: 157 -----NEDCLTLSVYVPTPASDKCQLRNDTGPCKAFFQNYYYDSTVGQCRQFVYGGCQGN 321

Query: 160 DEATLNPPDTD-IRDSGKKPVMLFLHGGSYMEGTGNMFDGSVLAAYGNVIVVTLNYRLGV 218
           +   L   D      S  KPVM+++HGG +  G+   +  SVL    +VIVV + YRL  
Sbjct: 322 ENNFLTLEDCQKACPSRSKPVMIWIHGGGFTLGSALDYTPSVLVTSRDVIVVVIQYRLDA 501

Query: 219 LGFLSTGDQAAKGNYGLLDQIQALRWLSENIAHFGGDPERITI 261
           LGFLS+GD  + GNY + DQ+ A++W+ +NI  FGGDP+ I++
Sbjct: 502 LGFLSSGDDVSPGNYAMWDQVMAVQWVKDNIQAFGGDPQSISL 630
>05383
          Length = 1210

 Score = 53.5 bits (127), Expect(2) = 7e-16,   Method: Compositional matrix adjust.
 Identities = 34/112 (30%), Positives = 53/112 (47%), Gaps = 2/112 (1%)
 Frame = +3

Query: 496 ADAAHGDELPYVFGVPMVG--ATDLFPCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPVPQ 553
           A   H DEL YVFG P++     + F  +++ +D  +S  VMT WTNFAK G+P    P 
Sbjct: 711 ARGEHADELHYVFGSPVIDDFMWNGFATSWTDDDKRVSDDVMTLWTNFAKYGNPT---PS 881

Query: 554 DTKFIHTKPNRFEEVVWSKFNSKEKQYLHIGLKPRVRDNYRANKVAFWLELV 605
            +            V W  +      Y+ IG+  R     RA +++ W++ +
Sbjct: 882 GSN-----------VTWLPWTPTSPNYMDIGVTDRPMSGLRAKQMSVWMDTI 1004

 Score = 48.9 bits (115), Expect(2) = 7e-16,   Method: Compositional matrix adjust.
 Identities = 52/225 (23%), Positives = 93/225 (41%), Gaps = 16/225 (7%)
 Frame = +1

Query: 291 SGTAISSWSVNYQPL-----KYTRLLAAKVGCDREDSTEAVECLRRKSSRELVD--QDVQ 343
           +G ++++WS  ++ +        R LA  + CD  DS   + CLR K +  +V+   +++
Sbjct: 61  AGVSMTTWSSAHRGVWPEARVQARTLAKGLHCDMSDSPAMLACLRTKDAMAIVNVSTEME 240

Query: 344 PARYHIAFXXXXXXX-----XXXXXXEILMQQGEFLNYDMLIGVNQGEGLKFVEDSAESE 398
            A   I F                    L++QG F +   + G N+ E       S    
Sbjct: 241 KAAGDILFRPVIEETFGQPGLFSGTVRDLLEQGLFNSVTAMRGYNKYESSSV---SDPDN 411

Query: 399 DGVSASAFDFTVSNFVD---NLYGYPEGKDVLRETIKFMYTDWADRDNGEMRRKTLLALF 455
           DG++ S F  ++ + V    + Y     +D     ++   T     D  ++R+   + L 
Sbjct: 412 DGITVSEFKSSLHDLVSWYVSRYSRLSAQDTEAALLEAYITAPNVTDPVDIRQAA-MQLR 588

Query: 456 TDHQWVAPAVATAKLH-ADYQSPVYFYTFYHHCQAEGRPEWADAA 499
           TD+ ++AP V   KL  A+   P Y Y F +       P+W  A+
Sbjct: 589 TDYSFIAPTVEEMKLTVANNPHPQYLYQFSYRSSNRQSPQWQGAS 723
>12073
          Length = 1602

 Score = 60.5 bits (145), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 55/209 (26%), Positives = 86/209 (41%), Gaps = 8/209 (3%)
 Frame = +1

Query: 381 GVNQGEGLKFVEDS------AESEDGVSASAFDFTVSNFVDNLYGYPEGKDVLRETIKFM 434
           GVN+ EG+ ++  +       ++   +S  AF   V     NL G  E  D   + I + 
Sbjct: 1   GVNKDEGMYWLLYAFPDLFPLDNSGSISDDAFKTLVHAL--NLNG-TESSD---KAIMYE 162

Query: 435 YTDWADRDNGEMRRKTLLALFTDHQWVAPAVATAKLHADYQS--PVYFYTFYHHCQAEGR 492
           Y D    ++ +  R     +  D  ++ P V  AK  +   S   VY Y++ H       
Sbjct: 163 YVDSVLPNDRQSYRDIADDIMGDEMFICPTVDFAKAFSSXLSNRSVYLYSYEHXLSNYPW 342

Query: 493 PEWADAAHGDELPYVFGVPMVGATDLFPCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPVP 552
           P+W    HG E+  VF +P+         N++  D  L   + TYWT+FAK G+PN    
Sbjct: 343 PQWTGVMHGYEIEAVFALPL-------DFNYTHTDQTLVNRLTTYWTHFAKHGNPNNETV 501

Query: 553 QDTKFIHTKPNRFEEVVWSKFNSKEKQYL 581
                           VW +  S++ QYL
Sbjct: 502 ---------------TVWPRLTSQDDQYL 543
>29534
          Length = 416

 Score = 51.6 bits (122), Expect = 1e-06,   Method: Composition-based stats.
 Identities = 31/86 (36%), Positives = 46/86 (53%), Gaps = 2/86 (2%)
 Frame = +2

Query: 254 GDPERITIFGSGAGASCVNLLILSHHSEGLFQKAIAQSGTAISSWSVNYQPLKYTRL--L 311
           G  + ITIFG  AGA+ V   ++S  S   F +AI QS + +S ++V  Q    +R   L
Sbjct: 2   GQQDSITIFGESAGAASVGFHLMSPLSMDHFTRAIMQSWSPLSDYAVMSQTKATSRAIKL 181

Query: 312 AAKVGCDREDSTEAVECLRRKSSREL 337
           A  +GCD +     V CLR+ S+  +
Sbjct: 182 AVILGCDHDSVPSRVHCLRQVSAENV 259
>20212
          Length = 587

 Score = 48.5 bits (114), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 32/114 (28%), Positives = 55/114 (48%), Gaps = 3/114 (2%)
 Frame = +2

Query: 448 RKTLLALFTDHQWVAPAVATAKL-HADYQSPVYFYTFYHHCQAEGRPEWADAAHGDELPY 506
           RK  + L TD   VAP +   ++ +  +  P Y Y F         P +     G ++ Y
Sbjct: 5   RKAYIRLRTDQFMVAPVLQETQMTYQAHAKPQYLYHFSFRSANRMVPAFQGHRTGMDVFY 184

Query: 507 VFGVPMVGATDL--FPCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPVPQDTKFI 558
           + G+P++  T L  F  +++ +D  ++  + T WTNFAK G+P       TK++
Sbjct: 185 MLGLPVMNITYLYNFVSSYTDDDRRVANDITTMWTNFAKYGNPTPEGYSGTKWL 346
>01645
          Length = 1116

 Score = 45.4 bits (106), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 26/60 (43%), Positives = 31/60 (51%)
 Frame = -1

Query: 489 AEGRPEWADAAHGDELPYVFGVPMVGATDLFPCNFSKNDVMLSAVVMTYWTNFAKTGDPN 548
            EGR       HG EL YVF     G        F+  +  LS+ +M +WTNFAKTGDPN
Sbjct: 678 CEGR-----VCHGSELVYVFHTEWAGN-----FTFTAAEEALSSQIMDFWTNFAKTGDPN 529
>12297
          Length = 808

 Score = 38.9 bits (89), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 26/89 (29%), Positives = 39/89 (43%), Gaps = 1/89 (1%)
 Frame = +2

Query: 523 FSKNDVMLSAVVMTYWTNFAKTGDPNQPVP-QDTKFIHTKPNRFEEVVWSKFNSKEKQYL 581
           F+ +D  L+       + FA  G P   +P QD              VW ++   ++QYL
Sbjct: 191 FNADDFTLATTFKRMLSTFAVHGVPRLDIPPQDAG------------VWPEYTMNQQQYL 334

Query: 582 HIGLKPRVRDNYRANKVAFWLELVPHLHN 610
            +   PRV       +VA WL+L+P L N
Sbjct: 335 SLEPVPRVDSYLYGKRVALWLDLLPSLVN 421
>35653
          Length = 381

 Score = 36.2 bits (82), Expect = 0.058,   Method: Composition-based stats.
 Identities = 28/107 (26%), Positives = 46/107 (42%), Gaps = 3/107 (2%)
 Frame = +2

Query: 498 AAHGDELPYVFGVPMVGATDLFPCNFSKNDVMLSAVVMTYWTNFAKTGDPN---QPVPQD 554
           A+H DEL Y+F        D  P   S  D  +S  +   W NFAK G P+    PV + 
Sbjct: 62  ASHADELSYLFQX----IDDESP--LSAEDAQVSVRLCQMWANFAKHGKPSDTWSPVLRQ 223

Query: 555 TKFIHTKPNRFEEVVWSKFNSKEKQYLHIGLKPRVRDNYRANKVAFW 601
            + ++ +   F           +  Y+ I  + +++ N  A ++ FW
Sbjct: 224 IRNLNGELEPF-----------QLDYMQIDWESKMKRNPDAERIDFW 331
>37200
          Length = 291

 Score = 30.8 bits (68), Expect = 2.5,   Method: Composition-based stats.
 Identities = 11/20 (55%), Positives = 15/20 (75%)
 Frame = -1

Query: 69 FLGVPYATPPLGARRFQPPE 88
          +L +PYA PPLG  RF+ P+
Sbjct: 66 YLAIPYAQPPLGELRFEKPQ 7
>28623
          Length = 1160

 Score = 29.6 bits (65), Expect = 4.9,   Method: Compositional matrix adjust.
 Identities = 15/51 (29%), Positives = 25/51 (49%)
 Frame = -2

Query: 98  NATTLPPACPQNLHGALPAIMLPVWFTDNLEAAATYVQNQSEDCLYLNLYV 148
           + +T+ P   QN+ GAL + +LP      +          +E+C +L LYV
Sbjct: 394 HTSTIWPDIKQNVQGALLSCVLPSVLQSQMSMTGLSTNKMNENCDHLRLYV 242
>06426
          Length = 1132

 Score = 29.3 bits (64), Expect = 6.9,   Method: Compositional matrix adjust.
 Identities = 25/104 (24%), Positives = 45/104 (43%)
 Frame = +2

Query: 498 AAHGDELPYVFGVPMVGATDLFPCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPVPQDTKF 557
            +H DEL Y+F       T  +  + +  +      ++  WT+FA T +PN     +T  
Sbjct: 671 VSHADELSYLFR-----NTKSWKLDKASREYRTIQRLVDIWTSFAATSNPN---CAETAH 826

Query: 558 IHTKPNRFEEVVWSKFNSKEKQYLHIGLKPRVRDNYRANKVAFW 601
           ++ +P R         N +  + L+I  +  + D   A K+ FW
Sbjct: 827 LNWEPAR---------NEQPNKVLNISDEIEIIDLPEAEKLKFW 931
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6680085|ref|NP_032190.1| rhophilin, Rho GTPase
binding protein 1 [Mus musculus]
         (643 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

26948                                                                 117   1e-40
03831                                                                  48   1e-05
38751                                                                  38   0.012
20073                                                                  37   0.017
03499                                                                  34   0.17 
20530                                                                  33   0.33 
33158                                                                  33   0.34 
17738                                                                  32   0.76 
26275                                                                  28   8.7  
>26948
          Length = 2380

 Score =  117 bits (292), Expect(2) = 1e-40,   Method: Compositional matrix adjust.
 Identities = 66/172 (38%), Positives = 97/172 (56%), Gaps = 20/172 (11%)
 Frame = -2

Query: 392  PH-EPLGPTLPQHPEDRRKLAKAHLKRAILGQEEALRLHTLCRVLRKVDLLQVVVTQALR 450
            PH E  G  LP+  E+R  L K HL+ A+L  EEALR+H LC+ +RK+DL + ++ +   
Sbjct: 1977 PHDENNGLKLPKTQEERNILGKGHLREAVLSHEEALRVHDLCKQMRKIDLFRNILQKMHE 1798

Query: 451  RSLAKYSQLEREDDFFEATEAPDIQPKTHQTPE------------------GPLSVFSTK 492
            RS+ K+S LE EDDF E    P I  K+    E                  GP+++F++K
Sbjct: 1797 RSIEKFSSLEEEDDFTELLTVPRIVGKSEADTEPTPPDFSQTKSNDIFTKLGPIAIFNSK 1618

Query: 493  NRWQLVGPVHMTR-GEGGFGFTLRGDSPVLIAAVVPGGQAESAGLKEGDYIV 543
            N+W     V + R    GFGF++RGDSPV++A +     A  +G+K GD++V
Sbjct: 1617 NQWAAPRQVVLERLPTEGFGFSVRGDSPVIVADIELDSVAGRSGMKVGDFVV 1462

 Score = 68.2 bits (165), Expect(2) = 1e-40,   Method: Compositional matrix adjust.
 Identities = 39/110 (35%), Positives = 56/110 (50%)
 Frame = -1

Query: 263  LRENFSHAPSPDMSAASLSMLEQLMIAQAQECIFKGLLLPASATPDICPDXXXXXXXXXX 322
            L  +F +APS DM + +LSML  L++AQAQEC+ +  L+       +             
Sbjct: 2368 LESHFRNAPSMDMQSDTLSMLCVLLLAQAQECVMEERLMQWGKEGVVV--NAQLAREAAM 2195

Query: 323  XXTEYGLVHRAMAQPPVRDYLPASWTNLAHVKAEHFCALAHYHAAMALCE 372
               +Y   HR M+   V+ YLP  W ++A  K   +  LAHY+ AMAL E
Sbjct: 2194 VSEKYRETHRKMSSEAVKSYLPFPWISMAQTKHYFYKGLAHYYVAMALLE 2045
>03831
          Length = 1143

 Score = 48.1 bits (113), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 28/70 (40%), Positives = 40/70 (57%), Gaps = 3/70 (4%)
 Frame = +3

Query: 509 GFGFTLRG--DSP-VLIAAVVPGGQAESAGLKEGDYIVSVNGQPCKWWKHLEVVTQLRSM 565
           G+GF L    D P   I +V P   AE+ GLKEGD I+ VNG+  +   H  V+  ++S 
Sbjct: 615 GYGFNLHAEKDKPGQYIGSVDPNSPAETGGLKEGDRIIEVNGENIETTNHTAVIQNIKSR 794

Query: 566 GEEGVSLQVV 575
           G++  S+ VV
Sbjct: 795 GDK-TSMLVV 821

 Score = 47.0 bits (110), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 26/63 (41%), Positives = 36/63 (57%), Gaps = 3/63 (4%)
 Frame = +3

Query: 509 GFGFTL---RGDSPVLIAAVVPGGQAESAGLKEGDYIVSVNGQPCKWWKHLEVVTQLRSM 565
           G+GF L   +G +   I  V  G  AE+AGLK GD IV VNG       H +VV ++++ 
Sbjct: 168 GYGFNLHAEKGKAGQFIGKVDEGSPAEAAGLKAGDRIVEVNGTNIGNENHQQVVGRIKAG 347

Query: 566 GEE 568
           G+E
Sbjct: 348 GDE 356
>38751
          Length = 329

 Score = 38.1 bits (87), Expect = 0.012,   Method: Composition-based stats.
 Identities = 22/65 (33%), Positives = 33/65 (50%)
 Frame = +3

Query: 518 SPVLIAAVVPGGQAESAGLKEGDYIVSVNGQPCKWWKHLEVVTQLRSMGEEGVSLQVVSL 577
           +P+++  +  G QAE  GL  GD I+ VNG       H E VT +R+     +++Q    
Sbjct: 33  TPIVVYVIEEGCQAEQQGLNIGDRILDVNGTDFTHLTHAEAVTIMRNAWNVIMTVQ---- 200

Query: 578 LPSPE 582
            P PE
Sbjct: 201 -PCPE 212
>20073
          Length = 582

 Score = 37.4 bits (85), Expect = 0.017,   Method: Composition-based stats.
 Identities = 25/71 (35%), Positives = 37/71 (52%), Gaps = 5/71 (7%)
 Frame = +3

Query: 509 GFGFTLRG----DSPVLIAAVVPGGQAESAG-LKEGDYIVSVNGQPCKWWKHLEVVTQLR 563
           G GF + G     SP+ I+ ++PGG A+    LK GD ++SVNG   +   H E   +L 
Sbjct: 3   GLGFNVMGGKEQSSPIYISRIIPGGVADRLNCLKRGDQLLSVNGVSVEGEYH-EKAVELL 179

Query: 564 SMGEEGVSLQV 574
            + +  V L V
Sbjct: 180 KLAQGSVRLVV 212
>03499
          Length = 1247

 Score = 34.3 bits (77), Expect = 0.17,   Method: Compositional matrix adjust.
 Identities = 24/95 (25%), Positives = 50/95 (52%), Gaps = 2/95 (2%)
 Frame = -3

Query: 483 EGPLSVFSTKNRWQLVGPVHMTRGEGGFGFTLRGDSPV--LIAAVVPGGQAESAGLKEGD 540
            GP  + +  ++ +++  +++ RG+ GFGFT+  DSP    +  ++  G+ ++  L+E D
Sbjct: 474 NGPPDLVTVTSKPEILS-INIVRGQMGFGFTI-ADSPYGQKVKQILDKGRCKT--LQEND 307

Query: 541 YIVSVNGQPCKWWKHLEVVTQLRSMGEEGVSLQVV 575
            +  +N    K   H ++V  L+     GV  Q++
Sbjct: 306 LLQEINRVDVKRMTHAQIVQVLKDC-PIGVDTQII 205
>20530
          Length = 431

 Score = 33.1 bits (74), Expect = 0.33,   Method: Compositional matrix adjust.
 Identities = 18/47 (38%), Positives = 28/47 (59%)
 Frame = +1

Query: 516 GDSPVLIAAVVPGGQAESAGLKEGDYIVSVNGQPCKWWKHLEVVTQL 562
           G  PV ++ V    +  ++GL+EGD +V+VNG  C     + +VTQL
Sbjct: 7   GGCPVYVSQVT--NEERASGLQEGDIVVAVNGVSC---GGIHMVTQL 132
>33158
          Length = 1075

 Score = 33.1 bits (74), Expect = 0.34,   Method: Compositional matrix adjust.
 Identities = 22/48 (45%), Positives = 29/48 (60%), Gaps = 3/48 (6%)
 Frame = +2

Query: 498 VGPVHMTRGEGGFGFTLR--GDSPVLIAAVVPGGQAESAGL-KEGDYI 542
           V  +H+ +     G T++  GDS VLIA +V GG AE +GL  EGD I
Sbjct: 935 VKIIHLEKTNEHLGATVKNEGDS-VLIARIVKGGAAEKSGLLHEGDEI 1075
>17738
          Length = 441

 Score = 32.0 bits (71), Expect = 0.76,   Method: Composition-based stats.
 Identities = 15/45 (33%), Positives = 24/45 (53%), Gaps = 2/45 (4%)
 Frame = -1

Query: 393 HEPLGPTLPQHP--EDRRKLAKAHLKRAILGQEEALRLHTLCRVL 435
           HEP+  T+PQ P  E+   + K HL    +      + HTLC+++
Sbjct: 138 HEPINITVPQDPNIENISNVCKEHLSTNSISINILTKYHTLCKLI 4
>26275
          Length = 896

 Score = 28.5 bits (62), Expect = 8.7,   Method: Compositional matrix adjust.
 Identities = 8/20 (40%), Positives = 12/20 (60%)
 Frame = +2

Query: 595 WNQRECGFETPMPTRTRPWP 614
           W++ +C    P P+  RPWP
Sbjct: 686 WSREQCSLRKPRPSTFRPWP 745
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|68533242|ref|NP_473434.2| ubiquitin protein ligase
E3B [Mus musculus]
         (1070 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

05501                                                                 165   1e-40
02386                                                                 157   2e-38
13725                                                                  94   2e-19
21239                                                                  88   1e-17
05524                                                                  60   6e-09
31463                                                                  55   2e-07
19738                                                                  55   2e-07
33148                                                                  52   2e-06
32927                                                                  47   4e-05
21977                                                                  30   5.6  
08541                                                                  30   7.6  
>05501
          Length = 1740

 Score =  165 bits (417), Expect = 1e-40,   Method: Compositional matrix adjust.
 Identities = 111/377 (29%), Positives = 187/377 (49%), Gaps = 3/377 (0%)
 Frame = -1

Query: 694  EDGYEQLRQLSQHAMKGVIRVKFVNDLGVDEAGIDQDGVFKEFLEEIIKRVFDPALNLFK 753
            ED + Q+ +L    ++  + + F       E G+D  GV +E+   +   V +P   LF+
Sbjct: 1680 EDSFAQIMRLQPFDLRRRLYIIFKG-----EEGLDYGGVAREWFFHLSHDVLNPMYCLFE 1516

Query: 754  TTSGDE-RLYPSPTSYIHENYLQLFEFVGKMLGKAVYEGIVVDVPFASFFLSQMLGHHHS 812
              S +   L  +P S ++ ++L  F F+G+ +  A+Y G  +D  F   F  +ML     
Sbjct: 1515 YASNNNYSLQINPASSVNPDHLLYFRFIGRFIAMALYHGKFIDSGFTLPFYKRMLSKK-- 1342

Query: 813  VFYSSVDELPSLDSEFYKNLTSIKRYDGDIADLGLTLSY--DEDVMGQLVCHELVPGGKT 870
                ++ +L ++D E++++L  +K  D ++ + GL L +  D +V+G++  HEL PGG  
Sbjct: 1341 ---LTLKDLETIDGEYFQSLQWVK--DNNVEESGLELFFCADFEVLGKVENHELKPGGSE 1177

Query: 871  IPVTDENKISYIHLMAHFRMHTQIKNQTAALISGFRSIIKPEWIRMFSTPELQRLISGDN 930
            I VT+ENK  Y++LM  +R    ++ QT A + GF  ++  +W++ F   EL+ ++ G  
Sbjct: 1176 IKVTEENKEEYLNLMTQWRFSRGVEEQTKAFLEGFNEVVPLQWLQYFDERELELMLCG-M 1000

Query: 931  AEIDLEDLKKHTVYYGGFHGSHRVIIWLWDILASDFTPEERAMFLKFVTSCSRPPLLGFA 990
             E+D++D +++T+ Y  +  + + + W W  +  +   E+R   L+FVT   R P+ GFA
Sbjct: 999  QEVDVDDWERNTI-YRHYQRNSKQVTWFWKFV-REIDNEKRTRLLQFVTGTCRLPVGGFA 826

Query: 991  YLKPPFSIRCVEVSDDQDTGDTLGSVLRGFFTIRKREPGGRLPTSSTCFNLLKLPNYSKK 1050
             L                    +GS     F I K      LP S TCFN + LP Y   
Sbjct: 825  EL--------------------MGSNGPQRFCIEKVGKETWLPRSHTCFNRIDLPPYRSY 706

Query: 1051 SVLREKLRYAISMNTGF 1067
              L EKL  AI    GF
Sbjct: 705  EQLVEKLNLAIEETEGF 655
>02386
          Length = 2222

 Score =  157 bits (398), Expect = 2e-38,   Method: Compositional matrix adjust.
 Identities = 121/393 (30%), Positives = 192/393 (48%), Gaps = 7/393 (1%)
 Frame = +2

Query: 685  ITIRRSRMLEDGYEQLRQLSQHAMKGVIRVKFVNDLGVDEAGIDQDGVFKEFLEEIIKRV 744
            + +RR  + ED + +L + +    K    + F       E G D  G+ +E+   I + +
Sbjct: 335  VHVRREHVFEDSFRELFRRNPDEWKQRFYIVFEG-----EEGQDAGGLLREWYLIISREI 499

Query: 745  FDPALNLFKTTSGDERLYP-SPTSYIHENYLQLFEFVGKMLGKAVYEGIVVDVPFASFFL 803
            F+    LFK    D   Y  +P+S+ + N+L  F+FVG+++ KA+Y+  +++  F   F 
Sbjct: 500  FNENYVLFKRYPRDGVTYTINPSSHFNSNHLSYFKFVGRIIAKAIYDNKLLECYFTRSFY 679

Query: 804  SQMLGHHHSVFYSSVDELPSLDSEFYKNLTSIKRYDGDIADLG-----LTLSYDEDVMGQ 858
              +LG    V Y+   ++   D  FY++L  +   + DI D+G     L  S + +  G 
Sbjct: 680  KHVLG--LPVKYT---DMECEDIMFYQSLVFL--LENDITDMGAALGDLNFSAEVEEFGV 838

Query: 859  LVCHELVPGGKTIPVTDENKISYIHLMAHFRMHTQIKNQTAALISGFRSIIKPEWIRMFS 918
                +L+  G  I VT+ENK  Y+ L+   +M   I+ Q  A + GF  II  + + +F+
Sbjct: 839  RETRDLIENGSNIGVTEENKREYVKLVCQMKMTGAIRQQLNAFLEGFYDIIPKKLVAIFT 1018

Query: 919  TPELQRLISGDNAEIDLEDLKKHTVYYGGFHGSHRVIIWLWDILASDFTPEERAMFLKFV 978
              EL+ LISG    ID++DLK +T Y+  +  +   I W W  L S F   ERA FL+FV
Sbjct: 1019 EQELELLISG-LPTIDIDDLKANTEYH-KYQPTSLQIQWFWRALRS-FDQAERANFLQFV 1189

Query: 979  TSCSRPPLLGFAYLKPPFSIRCVEVSDDQDTGDTLGSVLRGFFTIRKREPGGRLPTSSTC 1038
            T  S+ PL GFA L+     +  ++  D  + D                   RLP++ TC
Sbjct: 1190 TGTSKVPLQGFATLEGMNGHQKFQIHRDDRSTD-------------------RLPSAHTC 1312

Query: 1039 FNLLKLPNYSKKSVLREKLRYAIS-MNTGFELS 1070
            FN L LP Y     LR+ L  A+S  + GF L+
Sbjct: 1313 FNQLDLPAYETYDKLRKMLLLAVSECSEGFGLA 1411
>13725
          Length = 700

 Score = 94.4 bits (233), Expect = 2e-19,   Method: Compositional matrix adjust.
 Identities = 66/232 (28%), Positives = 118/232 (50%), Gaps = 4/232 (1%)
 Frame = +2

Query: 674 ETSSASPHVTH--ITIRRSRMLEDGYEQLRQLSQHAMKGVIRVKFVNDLGVDEAGIDQDG 731
           E  S  P   H  + + R  + ED Y Q+ ++    ++  + VKF       E G+D  G
Sbjct: 17  EFQSLQPQTGHCRLEVSREEIFEDSYRQVMKMRSKELRKRLMVKFHG-----EEGLDYGG 181

Query: 732 VFKEFLEEIIKRVFDPALNLFKTTSGD-ERLYPSPTSYIHENYLQLFEFVGKMLGKAVYE 790
           V +E+   +   + +P   LF+ +  D   L  +P S ++  +L  F FVG+++G A++ 
Sbjct: 182 VAREWFYLLSHEMLNPYYGLFQYSREDIYTLQINPDSGVNPEHLSYFHFVGRVIGMAIFH 361

Query: 791 GIVVDVPFASFFLSQMLGHHHSVFYSSVDELPSLDSEFYKNLTSIKRYDGDIAD-LGLTL 849
           G  +D  F   F  Q+LG       +++++L S+D + +++L  +   + +I + L  T 
Sbjct: 362 GHYLDGGFTMPFYKQLLGKP-----ATLEDLESVDPDLHRSLCWM--LENNIENVLEHTF 520

Query: 850 SYDEDVMGQLVCHELVPGGKTIPVTDENKISYIHLMAHFRMHTQIKNQTAAL 901
           S + +  G+L  +EL PGG    VT++NK  Y+ L  H+R+   I+ Q  AL
Sbjct: 521 SVEHNSFGKLREYELKPGGNDTKVTEDNKHEYVRLYVHWRLMRGIEAQFLAL 676
>21239
          Length = 1264

 Score = 88.2 bits (217), Expect = 1e-17,   Method: Compositional matrix adjust.
 Identities = 69/223 (30%), Positives = 105/223 (47%), Gaps = 1/223 (0%)
 Frame = +1

Query: 841  DIADLGLTLSYDEDVMGQLVCHELVPGGKTIPVTDENKISYIHLMAHFRMHTQIKNQTAA 900
            DI DLGL       + G  +  EL  GGK IPVT  N   Y+ L+ H+ +   +  Q  A
Sbjct: 73   DIQDLGLYFH----LPGYNI--ELKKGGKDIPVTLHNLHEYLQLVIHWSLVEGVSRQFEA 234

Query: 901  LISGFRSIIKPEWIRMFSTPELQRLISGDN-AEIDLEDLKKHTVYYGGFHGSHRVIIWLW 959
               GF S+     ++ F   EL++L  G      +++ L ++     G+    + +++L+
Sbjct: 235  FREGFESVFSLSSLQCFYPEELEQLFCGSQWGPWEVKMLMENCRPDHGYTHDSKAVVFLY 414

Query: 960  DILASDFTPEERAMFLKFVTSCSRPPLLGFAYLKPPFSIRCVEVSDDQDTGDTLGSVLRG 1019
             +LAS F  +++  FL+FVT   R P+ GF  L PP +I    V    + G+        
Sbjct: 415  QLLAS-FDLQQQRHFLQFVTGSPRLPVGGFRSLTPPLTI----VRKTFEAGEN------- 558

Query: 1020 FFTIRKREPGGRLPTSSTCFNLLKLPNYSKKSVLREKLRYAIS 1062
                    P   LP+  TC N LKLP+YS   ++R KL  A S
Sbjct: 559  --------PDDFLPSVMTCVNYLKLPDYSSIDIMRHKLHTAAS 663
>05524
          Length = 2623

 Score = 59.7 bits (143), Expect = 6e-09,   Method: Compositional matrix adjust.
 Identities = 38/124 (30%), Positives = 59/124 (47%)
 Frame = +2

Query: 938  LKKHTVYYGGFHGSHRVIIWLWDILASDFTPEERAMFLKFVTSCSRPPLLGFAYLKPPFS 997
            L K    Y G   +  ++ W W+++  +F+  ER++FL+FV   +R P     +    F 
Sbjct: 518  LLKSVATYKGIEATAPLVQWFWEVM-DEFSTAERSLFLRFVWGRTRLPRTIADFRGRDFV 694

Query: 998  IRCVEVSDDQDTGDTLGSVLRGFFTIRKREPGGRLPTSSTCFNLLKLPNYSKKSVLREKL 1057
            ++ ++                     +   P   LP S TCF LLK+P YS K VL+EKL
Sbjct: 695  LQVLD---------------------KYNPPDHFLPESYTCFFLLKMPRYSDKLVLKEKL 811

Query: 1058 RYAI 1061
            +YAI
Sbjct: 812  KYAI 823
>31463
          Length = 495

 Score = 55.1 bits (131), Expect = 2e-07,   Method: Composition-based stats.
 Identities = 25/40 (62%), Positives = 28/40 (70%)
 Frame = +1

Query: 1031 RLPTSSTCFNLLKLPNYSKKSVLREKLRYAISMNTGFELS 1070
            RLPT+STC NLLKLP +  +  LR KL YAI    GFELS
Sbjct: 19   RLPTASTCMNLLKLPEFKDEKTLRTKLLYAIESGAGFELS 138
>19738
          Length = 375

 Score = 54.7 bits (130), Expect = 2e-07,   Method: Composition-based stats.
 Identities = 27/79 (34%), Positives = 44/79 (55%)
 Frame = +2

Query: 863 ELVPGGKTIPVTDENKISYIHLMAHFRMHTQIKNQTAALISGFRSIIKPEWIRMFSTPEL 922
           EL+PGG  I VT++NK+SY+  +A +R+ T +K +  + + G   +I    + +F   EL
Sbjct: 8   ELMPGGGNIRVTNKNKLSYLDCLAQYRLATSVKEEVESFLRGLNELIPDNLLSIFDEYEL 187

Query: 923 QRLISGDNAEIDLEDLKKH 941
           + L+ G      L D K H
Sbjct: 188 ELLMCG-MGTYSLADFKIH 241
>33148
          Length = 687

 Score = 51.6 bits (122), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 39/119 (32%), Positives = 51/119 (42%)
 Frame = +3

Query: 942  TVYYGGFHGSHRVIIWLWDILASDFTPEERAMFLKFVTSCSRPPLLGFAYLKPPFSIRCV 1001
            T YY     +   + + W+ + + F+ E+R+ FL+FVT   R P         P  I   
Sbjct: 27   TTYYDDLEETDIRVKYFWEAMKA-FSNEDRSRFLRFVTGRRRLPA--------PLVI--- 170

Query: 1002 EVSDDQDTGDTLGSVLRGFFTIRKREPGGRLPTSSTCFNLLKLPNYSKKSVLREKLRYA 1060
                    GDT+ S                LP SSTC N+L LP YS   V  EKLRYA
Sbjct: 171  ----STGKGDTIDS----------------LPESSTCANMLYLPYYSSAKVAEEKLRYA 287
>32927
          Length = 514

 Score = 47.0 bits (110), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 23/40 (57%), Positives = 27/40 (67%)
 Frame = +3

Query: 1022 TIRKREPGGRLPTSSTCFNLLKLPNYSKKSVLREKLRYAI 1061
             + K  P   LP S TCF LLK+P YS K+VL EKL+YAI
Sbjct: 21   VLEKNPPDHFLPESYTCFFLLKMPRYSCKTVLLEKLKYAI 140
>21977
          Length = 1121

 Score = 30.0 bits (66), Expect = 5.6,   Method: Composition-based stats.
 Identities = 26/109 (23%), Positives = 42/109 (38%)
 Frame = -1

Query: 66  SGSSKRSALCIFKIARRLLFICKTTEDSERLEKLCRSILNSMDAENEPKVWYVSLALSKD 125
           S  +KR A  +FK  R  + +CK   D+  +  +CR IL    + ++  +  V     KD
Sbjct: 986 SAKNKRLACVMFKHVRSGITLCKQRYDAVVISLVCR*ILTRYLSPHDALIEIVHGLPFKD 807

Query: 126 LTLLWIKQIKSILWHCCELLGQLKPEILQDSRLITLYLTMLVTFTDTST 174
               W          C     Q    +    R+ + Y+ +L  F  T T
Sbjct: 806 YVTNWQHIYXXATPQCWNYASQCCKSV-NKQRIKSCYIILLTQFVHTHT 663
>08541
          Length = 3044

 Score = 29.6 bits (65), Expect = 7.6,   Method: Compositional matrix adjust.
 Identities = 23/84 (27%), Positives = 34/84 (40%), Gaps = 1/84 (1%)
 Frame = -1

Query: 643  LQHIPHVV-PHKNRVLLFRNMVIKEKEKLGLVETSSASPHVTHITIRRSRMLEDGYEQLR 701
            + H PH   PHK R     NM  + K+    + TS A PH  H  ++          Q  
Sbjct: 1175 ISHTPHTSDPHKKR----HNMPSEXKKTSCCLPTSXAVPHNHHXPVK----------QKC 1038

Query: 702  QLSQHAMKGVIRVKFVNDLGVDEA 725
            + +Q A  G   + F ++   D A
Sbjct: 1037 KXTQXAAPGAXXLGFRDEPSADTA 966
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|10257421|ref|NP_062278.2| centrin 2 [Mus musculus]
         (172 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

22063                                                                 160   2e-40
14945                                                                 155   6e-39
14594                                                                 117   2e-27
18171                                                                  75   1e-14
14366                                                                  72   8e-14
05237                                                                  71   2e-13
06641                                                                  65   1e-11
26610                                                                  63   5e-11
01019                                                                  60   5e-10
20251                                                                  59   1e-09
38338                                                                  54   5e-08
17484                                                                  52   8e-08
16255                                                                  47   4e-06
07385                                                                  45   2e-05
08108                                                                  44   3e-05
04697                                                                  43   7e-05
19942                                                                  41   3e-04
28617                                                                  41   3e-04
11425                                                                  40   6e-04
32088                                                                  39   0.001
19912                                                                  36   0.007
17977                                                                  36   0.010
22273                                                                  34   0.026
01491                                                                  34   0.035
00167                                                                  33   0.069
26849                                                                  33   0.076
04643                                                                  32   0.10 
27864                                                                  32   0.14 
07678                                                                  31   0.22 
03732                                                                  31   0.22 
28023                                                                  31   0.23 
26019                                                                  29   0.76 
05230                                                                  28   1.4  
01401                                                                  27   3.6  
33397                                                                  26   7.0  
>22063
          Length = 688

 Score =  160 bits (406), Expect = 2e-40,   Method: Compositional matrix adjust.
 Identities = 85/132 (64%), Positives = 96/132 (72%)
 Frame = +3

Query: 3   SNFKKTTMASSAQRKRMSPKPELTEDQKQEIREAFDLFDADGTGTIDIKELKVAMRALGF 62
           SNFKKTT+A    RK+  PK ELTE+QKQEIREAFDLFDADG+GTID KELKVAMRALGF
Sbjct: 90  SNFKKTTLAGGG-RKKTGPKCELTEEQKQEIREAFDLFDADGSGTIDAKELKVAMRALGF 266

Query: 63  XXXXXXXXXXXXXXXXXGTGKMNFSDFLTVMTQKMSEKDTKEEILKAFKLFDDDETGKIS 122
                            GTG ++F+DFLT+MTQKMSEKD KEEILKAF+LFDDDETGK  
Sbjct: 267 EPKKEEIKKMIAEIDKEGTGTIDFNDFLTIMTQKMSEKDAKEEILKAFRLFDDDETGKNL 446

Query: 123 FKNLKRVAKELG 134
           F   +   K +G
Sbjct: 447 FPQFETSRKRIG 482

 Score =  102 bits (255), Expect = 6e-23,   Method: Compositional matrix adjust.
 Identities = 49/54 (90%), Positives = 53/54 (98%)
 Frame = +1

Query: 119 GKISFKNLKRVAKELGENLTDEELQEMIDEADRDGDGEVNEQEFLRIMKKTSLY 172
            KISF+NLKRVAKELGENLTDEELQEMIDEADRDGDGE+N++EFLRIMKKTSLY
Sbjct: 436 AKISFRNLKRVAKELGENLTDEELQEMIDEADRDGDGEINQEEFLRIMKKTSLY 597
>14945
          Length = 1337

 Score =  155 bits (393), Expect = 6e-39,   Method: Compositional matrix adjust.
 Identities = 84/135 (62%), Positives = 96/135 (71%)
 Frame = +1

Query: 3   SNFKKTTMASSAQRKRMSPKPELTEDQKQEIREAFDLFDADGTGTIDIKELKVAMRALGF 62
           SNFKKT++A    RK+  PK ELTE+QKQEIREAFDLFDADG+GTID KELKVAMRALGF
Sbjct: 31  SNFKKTSLAGGG-RKKTGPKCELTEEQKQEIREAFDLFDADGSGTIDAKELKVAMRALGF 207

Query: 63  XXXXXXXXXXXXXXXXXGTGKMNFSDFLTVMTQKMSEKDTKEEILKAFKLFDDDETGKIS 122
                            GTG ++F+DFLT+MTQKMSEKD KEEILKAF+LFDDDETGK  
Sbjct: 208 EPKKEEIKKMIAEIDKEGTGTIDFNDFLTIMTQKMSEKDAKEEILKAFRLFDDDETGKNL 387

Query: 123 FKNLKRVAKELGENL 137
              L+   +  G  L
Sbjct: 388 LPQLETGGQGAGREL 432

 Score =  102 bits (255), Expect = 6e-23,   Method: Compositional matrix adjust.
 Identities = 49/54 (90%), Positives = 53/54 (98%)
 Frame = +2

Query: 119 GKISFKNLKRVAKELGENLTDEELQEMIDEADRDGDGEVNEQEFLRIMKKTSLY 172
            KISF+NLKRVAKELGENLTDEELQEMIDEADRDGDGE+N++EFLRIMKKTSLY
Sbjct: 377 AKISFRNLKRVAKELGENLTDEELQEMIDEADRDGDGEINQEEFLRIMKKTSLY 538
>14594
          Length = 1014

 Score =  117 bits (294), Expect = 2e-27,   Method: Compositional matrix adjust.
 Identities = 65/142 (45%), Positives = 85/142 (59%)
 Frame = +3

Query: 25  LTEDQKQEIREAFDLFDADGTGTIDIKELKVAMRALGFXXXXXXXXXXXXXXXXXGTGKM 84
           LT++Q  E +EAF LFD DG GTI   EL   MR+LG                  G G +
Sbjct: 423 LTDEQVAEFKEAFSLFDKDGDGTITTSELGTVMRSLGQNPTENELQDMINEVDADGNGTI 602

Query: 85  NFSDFLTVMTQKMSEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQE 144
           +F +FL +M +KM + D +EE+ +AF++FD D  G IS   L+ V   LGE LTDEE+ E
Sbjct: 603 DFEEFLHMMARKMKDTDCEEELREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDE 782

Query: 145 MIDEADRDGDGEVNEQEFLRIM 166
           MI EAD DGDG VN +EF+ +M
Sbjct: 783 MIKEADLDGDGMVNYEEFVTMM 848

 Score = 60.1 bits (144), Expect = 4e-10,   Method: Compositional matrix adjust.
 Identities = 33/82 (40%), Positives = 51/82 (62%), Gaps = 3/82 (3%)
 Frame = +3

Query: 90  LTVMTQKMSEKDTKEEILK---AFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMI 146
           L +M+Q+     T E++ +   AF LFD D  G I+   L  V + LG+N T+ ELQ+MI
Sbjct: 390 LLIMSQEHIVTLTDEQVAEFKEAFSLFDKDGDGTITTSELGTVMRSLGQNPTENELQDMI 569

Query: 147 DEADRDGDGEVNEQEFLRIMKK 168
           +E D DG+G ++ +EFL +M +
Sbjct: 570 NEVDADGNGTIDFEEFLHMMAR 635
>18171
          Length = 1131

 Score = 75.5 bits (184), Expect = 1e-14,   Method: Compositional matrix adjust.
 Identities = 39/88 (44%), Positives = 61/88 (69%), Gaps = 3/88 (3%)
 Frame = +3

Query: 82  GKMNFSDFLTVMTQKMSEKDTKEE---ILKAFKLFDDDETGKISFKNLKRVAKELGENLT 138
           GK++F DFLT+M + +  KD +EE   +L+A  L D D+TG IS   L+ V   LG+ LT
Sbjct: 90  GKVDFPDFLTLMARTVGSKDPQEEDDAMLEALTLLDKDQTGVISTALLRHVLTTLGDQLT 269

Query: 139 DEELQEMIDEADRDGDGEVNEQEFLRIM 166
            EE++E+I EAD++  G+V+ +EF+++M
Sbjct: 270 SEEVEELIKEADKEETGQVDYKEFIKMM 353
>14366
          Length = 499

 Score = 72.4 bits (176), Expect = 8e-14,   Method: Compositional matrix adjust.
 Identities = 39/139 (28%), Positives = 76/139 (54%)
 Frame = -3

Query: 29  QKQEIREAFDLFDADGTGTIDIKELKVAMRALGFXXXXXXXXXXXXXXXXXGTGKMNFSD 88
           +++E++EAF + +     TI + +L + +R++G                  G   +   +
Sbjct: 473 RQEELQEAF-IMNCSPDNTIALNKLGIVVRSIGRAPTESQLKTLTMEFENRGKRTLTLQE 297

Query: 89  FLTVMTQKMSEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDE 148
            + ++T+     +T + + +AF++FD +  G I+   L+ V   LGE L+DEE+ EMI E
Sbjct: 296 VIAIVTKYEFAPETSDNLREAFRIFDKEGNGMINAAELRHVLTHLGEKLSDEEVDEMIRE 117

Query: 149 ADRDGDGEVNEQEFLRIMK 167
           AD  GDG+V+  +F+++M+
Sbjct: 116 ADISGDGQVSYNDFVKVME 60

 Score = 39.3 bits (90), Expect = 8e-04,   Method: Compositional matrix adjust.
 Identities = 21/72 (29%), Positives = 34/72 (47%)
 Frame = -3

Query: 22  KPELTEDQKQEIREAFDLFDADGTGTIDIKELKVAMRALGFXXXXXXXXXXXXXXXXXGT 81
           K E   +    +REAF +FD +G G I+  EL+  +  LG                  G 
Sbjct: 278 KYEFAPETSDNLREAFRIFDKEGNGMINAAELRHVLTHLGEKLSDEEVDEMIREADISGD 99

Query: 82  GKMNFSDFLTVM 93
           G+++++DF+ VM
Sbjct: 98  GQVSYNDFVKVM 63
>05237
          Length = 472

 Score = 71.2 bits (173), Expect = 2e-13,   Method: Compositional matrix adjust.
 Identities = 37/68 (54%), Positives = 49/68 (72%)
 Frame = +3

Query: 99  EKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDGDGEVN 158
           E DT +E+ +AF++FD D  G IS   L+ V   LGE LTDEE+ EMI EAD DGDG+VN
Sbjct: 12  ETDTDDELREAFRVFDKDGNGFISASELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVN 191

Query: 159 EQEFLRIM 166
            +EF+++M
Sbjct: 192 YEEFVKMM 215

 Score = 42.7 bits (99), Expect = 8e-05,   Method: Compositional matrix adjust.
 Identities = 24/69 (34%), Positives = 33/69 (47%)
 Frame = +3

Query: 28 DQKQEIREAFDLFDADGTGTIDIKELKVAMRALGFXXXXXXXXXXXXXXXXXGTGKMNFS 87
          D   E+REAF +FD DG G I   EL+  M  LG                  G G++N+ 
Sbjct: 18 DTDDELREAFRVFDKDGNGFISASELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYE 197

Query: 88 DFLTVMTQK 96
          +F+ +MT K
Sbjct: 198EFVKMMTTK 224
>06641
          Length = 726

 Score = 65.1 bits (157), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 41/147 (27%), Positives = 76/147 (51%), Gaps = 5/147 (3%)
 Frame = +1

Query: 25  LTEDQKQEIREAFDLFDADGTGTIDIKELKVAMRALGFXXXXXXXX-XXXXXXXXXGTGK 83
           +  D +++I +AFD+FD +   T+D++E+   +R+LG                    TG 
Sbjct: 175 MIADTQKKITDAFDIFDHEANKTVDVREVGTIIRSLGCCPSEAELHDMLAEIEEEEPTGY 354

Query: 84  MNFSDFLTVMTQKMSEKDTK----EEILKAFKLFDDDETGKISFKNLKRVAKELGENLTD 139
           + F  FL +MT+ + E+  K    ++I+KAF++ D +  G +  + L +   E GE  T 
Sbjct: 355 IRFEKFLPMMTKVLMERRYKAVPEDQIVKAFQVLDVEGRGYLLQEELSKYMTEEGEPFTS 534

Query: 140 EELQEMIDEADRDGDGEVNEQEFLRIM 166
           EEL+EM+ +A     G +  +++  +M
Sbjct: 535 EELEEMMSQALDPEKGYIPYKDYASLM 615
>26610
          Length = 455

 Score = 63.2 bits (152), Expect = 5e-11,   Method: Compositional matrix adjust.
 Identities = 39/153 (25%), Positives = 74/153 (48%)
 Frame = +3

Query: 16  RKRMSPKPELTEDQKQEIREAFDLFDADGTGTIDIKELKVAMRALGFXXXXXXXXXXXXX 75
           R  +SP    T   K  + EAF+LFD D  G I   E+  A+R+LG              
Sbjct: 9   RSSLSP----TMSSKDAVSEAFELFDTDNDGKIAASEVGTAIRSLGHVVTDSDLRRLLSK 176

Query: 76  XXXXGTGKMNFSDFLTVMTQKMSEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGE 135
                 GK++ + F   + Q +   +  +++ +AF   D + +G +    L+ +   +G+
Sbjct: 177 AGIEPHGKVDMNRFRQ-LVQPLQGVNYTKQLDEAFNTIDKEGSGFVMATELRHLLTHMGD 353

Query: 136 NLTDEELQEMIDEADRDGDGEVNEQEFLRIMKK 168
            +TDEE   +++E + D +G V  +EF++++ +
Sbjct: 354 RITDEEFNALLEELEVDSNGRVRRKEFVQLLSR 452
>01019
          Length = 1705

 Score = 60.1 bits (144), Expect = 5e-10,   Method: Compositional matrix adjust.
 Identities = 31/55 (56%), Positives = 38/55 (69%)
 Frame = +1

Query: 112 LFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDGDGEVNEQEFLRIM 166
           +FD D  G IS   L+ V   LGE LTDEE+ EMI EAD DGDG+VN +EF+ +M
Sbjct: 43  VFDKDGNGFISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVTMM 207
>20251
          Length = 2203

 Score = 58.9 bits (141), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 47/154 (30%), Positives = 74/154 (48%)
 Frame = +3

Query: 14  AQRKRMSPKPELTEDQKQEIREAFDLFDADGTGTIDIKELKVAMRALGFXXXXXXXXXXX 73
           AQR   +      + Q QE +EAF++ D +  G ID ++L   + +LG            
Sbjct: 108 AQRATSNVFAMFDQSQIQEFKEAFNMIDQNRDGFIDKEDLGDMLASLG----KNPTEGQL 275

Query: 74  XXXXXXGTGKMNFSDFLTVMTQKMSEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKEL 133
                   G +NF+ FLT+   K++  D ++ I  AF  FD+D  G I    L+ +   +
Sbjct: 276 DEMMNXAPGPINFTMFLTMFGDKLNGTDPEDVIKNAFACFDEDGKGVIQEDRLRELLTTM 455

Query: 134 GENLTDEELQEMIDEADRDGDGEVNEQEFLRIMK 167
           G+  TD+E+ EM  +A     G  +  EF RI+K
Sbjct: 456 GDRFTDDEVDEMFRDAPIKR-GNFDYLEFTRILK 554
>38338
          Length = 463

 Score = 53.5 bits (127), Expect = 5e-08,   Method: Compositional matrix adjust.
 Identities = 29/66 (43%), Positives = 44/66 (66%), Gaps = 3/66 (4%)
 Frame = -2

Query: 96  KMSEKDTKEEILK---AFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRD 152
            M+++ T+E+I +   AF LFD D  G I+ K L  V + LG+N T+ ELQ+MI+E D D
Sbjct: 201 NMADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDAD 22

Query: 153 GDGEVN 158
           G+G ++
Sbjct: 21  GNGTID 4

 Score = 48.9 bits (115), Expect = 9e-07,   Method: Compositional matrix adjust.
 Identities = 23/57 (40%), Positives = 33/57 (57%)
 Frame = -2

Query: 5   FKKTTMASSAQRKRMSPKPELTEDQKQEIREAFDLFDADGTGTIDIKELKVAMRALG 61
           +++  +       + +   +LTE+Q  E +EAF LFD DG GTI  KEL   MR+LG
Sbjct: 246 YRRRVLVHHQTHSKSNMADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLG 76
>17484
          Length = 471

 Score = 52.4 bits (124), Expect = 8e-08,   Method: Compositional matrix adjust.
 Identities = 29/82 (35%), Positives = 52/82 (63%), Gaps = 3/82 (3%)
 Frame = -3

Query: 88  DFLTVMTQKM---SEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQE 144
           +FL ++  +M   SEKD  +E+  AF+ FD +  G IS   L++   ++G+ L+D +++ 
Sbjct: 322 EFLPLIVGRMKGGSEKD--KEMRDAFRAFDQNGDGVISISELRQAMAKMGQKLSDADVES 149

Query: 145 MIDEADRDGDGEVNEQEFLRIM 166
           +I + D+DGDG VN +EF + +
Sbjct: 148 IIRDVDKDGDGFVNYEEFTKFI 83
>16255
          Length = 767

 Score = 47.0 bits (110), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 23/34 (67%), Positives = 28/34 (82%)
 Frame = -2

Query: 133 LGENLTDEELQEMIDEADRDGDGEVNEQEFLRIM 166
           LGE LTDEE+ EMI EAD DGDG+VN +EF+ +M
Sbjct: 757 LGEKLTDEEVDEMIREADIDGDGQVNYEEFVTMM 656
>07385
          Length = 1292

 Score = 45.1 bits (105), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 20/32 (62%), Positives = 27/32 (84%)
 Frame = +3

Query: 135 ENLTDEELQEMIDEADRDGDGEVNEQEFLRIM 166
           + LTDEE+ EMI EAD DGDG+VN +EF+++M
Sbjct: 147 QKLTDEEVDEMIREADIDGDGQVNYEEFVKMM 242
>08108
          Length = 818

 Score = 44.3 bits (103), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 22/69 (31%), Positives = 39/69 (56%)
 Frame = +2

Query: 102 TKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDGDGEVNEQE 161
           T  E   AF +FD D +G IS   L    +  G ++TD++  E+I + D D +G+++  E
Sbjct: 119 TDAECQTAFAVFDTDGSGSISAGELGEALRAQGADITDDQTAELIKKYDSDSNGDIDTDE 298

Query: 162 FLRIMKKTS 170
           F ++++  S
Sbjct: 299 FRKLVEGES 325

 Score = 34.7 bits (78), Expect = 0.020,   Method: Compositional matrix adjust.
 Identities = 19/49 (38%), Positives = 26/49 (53%)
 Frame = +2

Query: 13  SAQRKRMSPKPELTEDQKQEIREAFDLFDADGTGTIDIKELKVAMRALG 61
           S Q  R S +  +      E + AF +FD DG+G+I   EL  A+RA G
Sbjct: 71  SRQSHRHSIQLTMAPLTDAECQTAFAVFDTDGSGSISAGELGEALRAQG 217
>04697
          Length = 559

 Score = 42.7 bits (99), Expect = 7e-05,   Method: Compositional matrix adjust.
 Identities = 21/67 (31%), Positives = 41/67 (61%)
 Frame = +1

Query: 100 KDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDGDGEVNE 159
           KD   + +K FK  D    G ++  +L+R  K++GE +T+++L +++ E D   + +V+ 
Sbjct: 349 KDEINQYVKRFKSLDYQNKGFVTVNDLRRYFKKMGEKVTEDQLHDILSEVDLSRNAQVDL 528

Query: 160 QEFLRIM 166
            EFL++M
Sbjct: 529 GEFLQLM 549
>19942
          Length = 367

 Score = 40.8 bits (94), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 21/30 (70%), Positives = 23/30 (76%)
 Frame = +2

Query: 129 VAKELGENLTDEELQEMIDEADRDGDGEVN 158
           V   LGE LTDEE+ EMI EAD DGDG+VN
Sbjct: 2   VMTNLGEKLTDEEVDEMIREADIDGDGQVN 91
>28617
          Length = 348

 Score = 40.8 bits (94), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 15/31 (48%), Positives = 27/31 (87%)
 Frame = -2

Query: 142 LQEMIDEADRDGDGEVNEQEFLRIMKKTSLY 172
            +EM++EAD +GDG++++ EF+RIM +T+L+
Sbjct: 344 WREMVEEADVNGDGQIDQSEFIRIMLQTNLF 252
>11425
          Length = 599

 Score = 39.7 bits (91), Expect = 6e-04,   Method: Compositional matrix adjust.
 Identities = 41/146 (28%), Positives = 66/146 (45%), Gaps = 6/146 (4%)
 Frame = -2

Query: 25  LTEDQKQEIREAFDLFD-ADGT-GTIDIKELKVAMRALGFXXXXXXXXXXXXXXXXXGTG 82
           L++   ++I E F+LFD  DG  G +D  ++      LG                  G  
Sbjct: 577 LSKSDIEDITEVFELFDFWDGRDGDVDAFKVGDMCFCLGLNPTQEIIRKNGGTTKL-GEK 401

Query: 83  KMNFSDFLTVMTQKMSEKDTK--EEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDE 140
                +FL +      EKDT    + ++ FK FD +  G IS   L+ +   LGE L+D+
Sbjct: 400 AYKLEEFLPIYETISKEKDTGTFADFMEGFKTFDREGQGFISAAELRHLLTGLGERLSDD 221

Query: 141 ELQEMIDEAD--RDGDGEVNEQEFLR 164
           E+ E+I   D   D +G V  ++F++
Sbjct: 220 EVDELIKATDTREDLEGNVKYEDFIQ 143
>32088
          Length = 1928

 Score = 38.9 bits (89), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 21/64 (32%), Positives = 32/64 (50%)
 Frame = +1

Query: 99  EKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDGDGEVN 158
           ++D   E+   F   DDD  G IS   L    + +G N+   EL+ ++ + D  GDG +N
Sbjct: 928 DEDQLTELRSVFDSIDDDNNGHISXGELDSAFRAVGLNIPGYELRTIMSKYDASGDGRLN 1107

Query: 159 EQEF 162
             EF
Sbjct: 1108MDEF 1119
>19912
          Length = 865

 Score = 36.2 bits (82), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 23/75 (30%), Positives = 38/75 (50%), Gaps = 1/75 (1%)
 Frame = +2

Query: 90  LTVMTQKMSEKDTKE-EILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDE 148
           L  M + M+  D+    ++  F  FD + T  I+    ++   E    L  +E+  ++DE
Sbjct: 623 LHPMVKLMAYIDSNNLRLVDFFNKFDKEGTMSITRDQFRQGLTEASIPLAGDEVDFLLDE 802

Query: 149 ADRDGDGEVNEQEFL 163
            DRDGDGE+N  E +
Sbjct: 803 LDRDGDGEINYSELV 847
>17977
          Length = 445

 Score = 35.8 bits (81), Expect = 0.010,   Method: Compositional matrix adjust.
 Identities = 15/63 (23%), Positives = 34/63 (53%)
 Frame = +3

Query: 104 EEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDGDGEVNEQEFL 163
            ++++AF+ +D D  GKI   +L+   ++    +    L+++ D  D + DG+++  EF 
Sbjct: 219 PDLIRAFRFYDKDGKGKIDIDDLREACRKFDVPIDVWLLEQVFDYCDENRDGQIDYLEFA 398

Query: 164 RIM 166
             +
Sbjct: 399 NFL 407
>22273
          Length = 297

 Score = 34.3 bits (77), Expect = 0.026,   Method: Compositional matrix adjust.
 Identities = 15/25 (60%), Positives = 21/25 (84%)
 Frame = +1

Query: 142 LQEMIDEADRDGDGEVNEQEFLRIM 166
           + EMI EAD DGDG+VN +EF+++M
Sbjct: 1   VDEMIREADIDGDGQVNYEEFVKMM 75
>01491
          Length = 1707

 Score = 33.9 bits (76), Expect = 0.035,   Method: Compositional matrix adjust.
 Identities = 14/39 (35%), Positives = 21/39 (53%)
 Frame = +2

Query: 24  ELTEDQKQEIREAFDLFDADGTGTIDIKELKVAMRALGF 62
           ++TE    +  + F LFD  G GT+  KEL    ++LG 
Sbjct: 107 QITEKMYNDASQTFHLFDKKGNGTVSTKELANVFKSLGL 223
>00167
          Length = 2176

 Score = 32.7 bits (73), Expect = 0.069,   Method: Compositional matrix adjust.
 Identities = 14/28 (50%), Positives = 20/28 (71%)
 Frame = +3

Query: 31  QEIREAFDLFDADGTGTIDIKELKVAMR 58
           +E+ E F  FD DGTGT+D +E  +A+R
Sbjct: 840 EELNEVFRRFDKDGTGTLDFEEFLLALR 923

 Score = 30.0 bits (66), Expect = 0.46,   Method: Compositional matrix adjust.
 Identities = 19/63 (30%), Positives = 33/63 (52%), Gaps = 1/63 (1%)
 Frame = +3

Query: 106 ILKAFKLFDDDETGKISFKNLKRVAKELG-ENLTDEELQEMIDEADRDGDGEVNEQEFLR 164
           I + F++ DD+   K+S        +E     +T EEL E+    D+DG G ++ +EFL 
Sbjct: 735 IGRKFRIMDDNRDRKLSVDEFIVGCRECRIAKMTSEELNEVFRRFDKDGTGTLDFEEFLL 914

Query: 165 IMK 167
            ++
Sbjct: 915 ALR 923
>26849
          Length = 649

 Score = 32.7 bits (73), Expect = 0.076,   Method: Compositional matrix adjust.
 Identities = 15/56 (26%), Positives = 33/56 (58%)
 Frame = +2

Query: 108 KAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDGDGEVNEQEFL 163
           +AF++ D D +  +S +  K+   ++  ++ + ++++M    D DG+G +N  EFL
Sbjct: 179 RAFRVMDKDGSKVLSLEEFKKGILDMHIDINEADIEDMFYRFDNDGNGTINMTEFL 346
>04643
          Length = 1881

 Score = 32.3 bits (72), Expect = 0.10,   Method: Compositional matrix adjust.
 Identities = 14/47 (29%), Positives = 31/47 (65%), Gaps = 1/47 (2%)
 Frame = +2

Query: 118 TGKISFKNLKRVAKEL-GENLTDEELQEMIDEADRDGDGEVNEQEFL 163
           +G +    +K   + L G+++++E L  ++ ++D DG+G++N +EFL
Sbjct: 2   SGCLCADEIKAHVRALTGDDMSEEALDNLVSKSDADGNGKINYKEFL 142
>27864
          Length = 343

 Score = 32.0 bits (71), Expect = 0.14,   Method: Compositional matrix adjust.
 Identities = 19/62 (30%), Positives = 30/62 (48%), Gaps = 1/62 (1%)
 Frame = +1

Query: 110 FKLFDDDETGKISFKNLKR-VAKELGENLTDEELQEMIDEADRDGDGEVNEQEFLRIMKK 168
           F+  D D +G IS   L++ ++         E ++ MI   DRD  G +N QEF  + K 
Sbjct: 31  FQRIDKDRSGNISVNELQQALSNGTWTPFNPETVRLMIGMFDRDNSGTINFQEFQALWKY 210

Query: 169 TS 170
            +
Sbjct: 211 VT 216
>07678
          Length = 958

 Score = 31.2 bits (69), Expect = 0.22,   Method: Compositional matrix adjust.
 Identities = 19/59 (32%), Positives = 29/59 (49%), Gaps = 1/59 (1%)
 Frame = +1

Query: 106 ILKAFKLFDDDETGKISFKNLKRVAKELG-ENLTDEELQEMIDEADRDGDGEVNEQEFL 163
           + + FK+ DDD    + FK  K+   E G      + +QEM    D+D  G ++  EFL
Sbjct: 325 LARKFKIMDDDGNRSLDFKEFKKGITEFGLTQFEGDVIQEMFTCFDKDZSGTIDFDEFL 501
>03732
          Length = 1114

 Score = 31.2 bits (69), Expect = 0.22,   Method: Compositional matrix adjust.
 Identities = 19/62 (30%), Positives = 30/62 (48%), Gaps = 1/62 (1%)
 Frame = -1

Query: 110  FKLFDDDETGKISFKNLKR-VAKELGENLTDEELQEMIDEADRDGDGEVNEQEFLRIMKK 168
            F+  D D +G IS   L++ ++         E ++ MI   DRD  G +N QEF  + K 
Sbjct: 1084 FQRIDKDRSGNISVNELQQALSNGTWTPFNPETVRLMIGMFDRDNSGTINFQEFQALWKY 905

Query: 169  TS 170
             +
Sbjct: 904  VT 899
>28023
          Length = 475

 Score = 31.2 bits (69), Expect = 0.23,   Method: Compositional matrix adjust.
 Identities = 14/31 (45%), Positives = 22/31 (70%)
 Frame = -1

Query: 138 TDEELQEMIDEADRDGDGEVNEQEFLRIMKK 168
           TD+E+ E+ID  D++ DG+V+  EF + M K
Sbjct: 475 TDQEVDEVIDYIDKNKDGKVDFSEFYKFMVK 383
>26019
          Length = 1561

 Score = 29.3 bits (64), Expect = 0.76,   Method: Compositional matrix adjust.
 Identities = 21/64 (32%), Positives = 35/64 (54%)
 Frame = +2

Query: 108 KAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDGDGEVNEQEFLRIMK 167
           K F+  D D +G +S      +  EL +N     +Q +ID  D DG+GEV+ +EF+  + 
Sbjct: 110 KRFRKLDLDNSGSLSIDEFMSLP-ELQQN---PLVQRVIDIFDTDGNGEVDFKEFIEGIS 277

Query: 168 KTSL 171
           + S+
Sbjct: 278 QFSV 289
>05230
          Length = 843

 Score = 28.5 bits (62), Expect = 1.4,   Method: Compositional matrix adjust.
 Identities = 21/84 (25%), Positives = 45/84 (53%), Gaps = 1/84 (1%)
 Frame = -2

Query: 83  KMNFSDFLTVMTQKMSEKDTKEEIL-KAFKLFDDDETGKISFKNLKRVAKELGENLTDEE 141
           ++   +++++M+   +  D K  +  K F  FD D +G  S +++    + +G  +T  +
Sbjct: 701 RLRMEEYISIMSD--ASVDMKTNMWRKLFAQFDTDGSGWASREDVIEGLENIGITIT-PD 531

Query: 142 LQEMIDEADRDGDGEVNEQEFLRI 165
           L+  I   D + DG++N  +FLR+
Sbjct: 530 LRAKIKAMDGNKDGKINYADFLRM 459
>01401
          Length = 1454

 Score = 27.3 bits (59), Expect = 3.6,   Method: Compositional matrix adjust.
 Identities = 13/37 (35%), Positives = 25/37 (67%), Gaps = 1/37 (2%)
 Frame = +1

Query: 131 KELGENLTDEELQEMIDEADRDGDGEV-NEQEFLRIM 166
           KE+G  ++ + +Q+++   D+D   EV + +EFLR+M
Sbjct: 133 KEMGVAISADRIQQLLTALDKDSKDEVIDYEEFLRVM 243
>33397
          Length = 1723

 Score = 26.2 bits (56), Expect = 7.0,   Method: Compositional matrix adjust.
 Identities = 13/44 (29%), Positives = 25/44 (56%), Gaps = 1/44 (2%)
 Frame = +2

Query: 126 LKRVAKELG-ENLTDEELQEMIDEADRDGDGEVNEQEFLRIMKK 168
              VAK +   +LT+  +  +    D + DGE++ +EF+ +MK+
Sbjct: 719 FHHVAKTVAMADLTEHVIDVVFTLFDENNDGELSNKEFVSVMKR 850
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|22779918|ref|NP_690034.1| purine-rich element binding
protein G isoform a [Mus musculus]
         (350 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

15221                                                                 162   2e-40
07342                                                                  30   1.4  
14307                                                                  28   4.2  
33561                                                                  28   6.4  
12528                                                                  28   7.4  
13560                                                                  27   10.0 
>15221
          Length = 1217

 Score =  162 bits (409), Expect = 2e-40,   Method: Compositional matrix adjust.
 Identities = 94/216 (43%), Positives = 123/216 (56%), Gaps = 6/216 (2%)
 Frame = -1

Query: 104  RKSKLTLSLSVAAELKDCLGDFIEHYAHLGLKGHRQEHGQSKEQVSRRRQKHSAPSPPVS 163
            +KS+L L++S AAE +D L DF EHYA LG                      +  SPP  
Sbjct: 1214 KKSRLLLAMSSAAEFRDYLTDFTEHYASLG--------------------PTNTESPP-- 1101

Query: 164  VGSEEHPHSVLKTDYIERDNRKYYLDLKENQRGRFLRI------RQTMMRGTGMIGYFGH 217
                      LK++ I +DNR+YYLDLKENQRGRFLR+       QT+ RG         
Sbjct: 1100 ------EDGKLKSETIVKDNRRYYLDLKENQRGRFLRVVCYEQVSQTIPRG--------- 966

Query: 218  SLGQDQTIVLPAQGMIEFRDALVQLIEDYGEGDIEERRCGDDDPLELPEGTSFRVDNKRF 277
              G    I +PAQGMIEFRDAL +L++++G  D E +        ELPE  S RV+NK F
Sbjct: 965  --GPRSQIAIPAQGMIEFRDALTELLDEFGTDDQEPQN-------ELPESRSMRVENKMF 813

Query: 278  YFDVGSNKYGIFLKVSEVRPPYRNTITVPFKAWTRF 313
            YFDVGSN+ G++L+VSEVR  +R  +T+P ++W RF
Sbjct: 812  YFDVGSNRRGVYLRVSEVRNNFRTAVTIPERSWARF 705

 Score = 42.4 bits (98), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 42/214 (19%), Positives = 83/214 (38%), Gaps = 5/214 (2%)
 Frame = -1

Query: 44   HYSASATPNQSGGTSEIQELASKRVDIQKKRFYLDVKQSSRGRFLKI-----AEVWIGRG 98
            HY AS  P  +    E  +L S+ +    +R+YLD+K++ RGRFL++         I RG
Sbjct: 1142 HY-ASLGPTNTESPPEDGKLKSETIVKDNRRYYLDLKENQRGRFLRVVCYEQVSQTIPRG 966

Query: 99   RQDNIRKSKLTLSLSVAAELKDCLGDFIEHYAHLGLKGHRQEHGQSKEQVSRRRQKHSAP 158
                  +S++ +      E +D L + ++ +                             
Sbjct: 965  GP----RSQIAIPAQGMIEFRDALTELLDEFG---------------------------- 882

Query: 159  SPPVSVGSEEHPHSVLKTDYIERDNRKYYLDLKENQRGRFLRIRQTMMRGTGMIGYFGHS 218
                    +E  + + ++  +  +N+ +Y D+  N+RG +LR+ +  +R           
Sbjct: 881  -----TDDQEPQNELPESRSMRVENKMFYFDVGSNRRGVYLRVSE--VRNNFRTA----- 738

Query: 219  LGQDQTIVLPAQGMIEFRDALVQLIEDYGEGDIE 252
                  + +P +    FRD L + ++     D E
Sbjct: 737  ------VTIPERSWARFRDVLSEFVDKSSLKDTE 654
>07342
          Length = 538

 Score = 30.0 bits (66), Expect = 1.4,   Method: Compositional matrix adjust.
 Identities = 16/41 (39%), Positives = 21/41 (51%)
 Frame = +1

Query: 226 VLPAQGMIEFRDALVQLIEDYGEGDIEERRCGDDDPLELPE 266
           + P  G I    AL Q  ED    D E +  GD+DPL++ E
Sbjct: 289 IFPHHGYIWNYGALPQTWEDPKHVDQETKTAGDNDPLDVCE 411
>14307
          Length = 816

 Score = 28.5 bits (62), Expect = 4.2,   Method: Compositional matrix adjust.
 Identities = 21/52 (40%), Positives = 28/52 (53%), Gaps = 1/52 (1%)
 Frame = +2

Query: 235 FRDALVQLIEDYGEGDIEERRC-GDDDPLELPEGTSFRVDNKRFYFDVGSNK 285
           +RD  +QLI    + D+ +R C G DDP E+ E   FR    +   DVGS K
Sbjct: 8   YRD--LQLIRQLPKQDLSDRYCKGLDDPSEVKEFRIFRELRDQVAMDVGSVK 157
>33561
          Length = 802

 Score = 27.7 bits (60), Expect = 6.4,   Method: Compositional matrix adjust.
 Identities = 15/52 (28%), Positives = 26/52 (50%)
 Frame = -1

Query: 280 DVGSNKYGIFLKVSEVRPPYRNTITVPFKAWTRFGENFIKYEEEMRKICNSH 331
            +  N+ GI + VS      R+T+ +P +    F    ++YEE +  +C SH
Sbjct: 520 TLAENQSGIPV-VSSSAGELRSTLRLPRQLGPPFSSLPVRYEERLHPLCQSH 368
>12528
          Length = 928

 Score = 27.7 bits (60), Expect = 7.4,   Method: Compositional matrix adjust.
 Identities = 16/41 (39%), Positives = 21/41 (51%)
 Frame = +3

Query: 226 VLPAQGMIEFRDALVQLIEDYGEGDIEERRCGDDDPLELPE 266
           + P  G I    AL Q  ED    D E +  GD+DPL++ E
Sbjct: 156 IFPHHGYIWNYGALPQTWEDPKHVDQETKTAGDNDPLDVCE 278
>13560
          Length = 978

 Score = 27.3 bits (59), Expect = 10.0,   Method: Compositional matrix adjust.
 Identities = 15/50 (30%), Positives = 24/50 (48%)
 Frame = +1

Query: 159 SPPVSVGSEEHPHSVLKTDYIERDNRKYYLDLKENQRGRFLRIRQTMMRG 208
           S  V++G+  H H  L+T   +  N +  LDL +N   R    +  M +G
Sbjct: 475 SANVNLGNLLHAHEDLETGLQKEPNNRALLDLMQNVNARLAPSQSQMAQG 624
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|51511739|ref|NP_001003930.1| reticulon 3 isoform 3
[Mus musculus]
         (255 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

19825                                                                 161   2e-40
>19825
          Length = 642

 Score =  161 bits (408), Expect = 2e-40,   Method: Compositional matrix adjust.
 Identities = 72/129 (55%), Positives = 102/129 (79%)
 Frame = +3

Query: 67  QVHDLIFWRDVKKTGFVFGTTLIMLLSLAAFSVISVVSYLILALLSVTISFRVYKSVIQA 126
           +V DLI+WRDV+KTG VFG  +++LLSLA FS++SV++YL LA+L+VT+SFR+YK+++ A
Sbjct: 255 RVLDLIYWRDVRKTGVVFGCMMLVLLSLACFSLMSVLAYLSLAVLTVTLSFRLYKNIMAA 434

Query: 127 VQKSEEGHPFKAYLDVDITLSSEAFHNYMNAAMVHVNKALKLIIRLFLVEDLVDSLKLAV 186
           VQKS +GHPFK YLD+DITL  E         + HVN++L  + RLFL+EDLVDS+K  +
Sbjct: 435 VQKSNDGHPFKQYLDLDITLKEERVSRVTQTVLQHVNRSLLELRRLFLIEDLVDSIKFGL 614

Query: 187 FMWLMTYVG 195
            +W++TY+G
Sbjct: 615 LLWVLTYIG 641
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|28076981|ref|NP_082083.1| cullin 5 [Mus musculus]
         (780 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

02265                                                                 163   3e-40
02365                                                                 153   2e-37
>02265
          Length = 1094

 Score =  163 bits (412), Expect = 3e-40,   Method: Compositional matrix adjust.
 Identities = 109/372 (29%), Positives = 186/372 (50%), Gaps = 9/372 (2%)
 Frame = +3

Query: 57  GSSKIHQALKEDILEFIKQAQARVL-SHQD--DTALLKAYIVEWRKFFTQCDILPKPFCQ 113
           G+  +   L + + +F+K     +L   QD  D  +L+ Y  +W  +     +L      
Sbjct: 30  GAQFVGHELYKRMKDFLKNYLVNLLKDGQDLLDEQVLQFYTRQWEDYQFSSKVLDGICAY 209

Query: 114 LEVTLLGKQSSNKKSNMEDSIVRKLMLDTWNESIFSNIKNRLQDSAMKLVHAERLGEAFD 173
           L    + ++       +    +  L L TW E +F  +  ++ ++ +KL+  ER GE  +
Sbjct: 210 LNRHWVRRECDEGTKGI--YYIYSLALITWRECLFKPLNKQVTNAVLKLIEKERNGETIN 383

Query: 174 SQLVIGVRESYVNLCSNPED------KLQIYRDNFEKAYLDSTERFYRTQAPSYLQQNGV 227
           ++LV GV   YV L  N ED       L +Y+D+FE  +LD TER+Y  ++  +L+QN V
Sbjct: 384 TRLVSGVINCYVELGLNEEDPSAKGPTLGVYKDHFETPFLDDTERYYTRESTEFLRQNPV 563

Query: 228 QNYMKYADAKLKEEEKRALRYLETRRECNSVEALMECCVNALVTSFKETILAECQGMIKR 287
             YMK A+ +LKEE+KR   YL      ++ ++L + C   L+    E    E Q ++  
Sbjct: 564 TEYMKKAEMRLKEEQKRVQTYLHE----STHDSLAKVCERVLIEKHLEIFHFEFQNLLDT 731

Query: 288 NETEKLHLMFSLMDKVPNGIEPMLKDLEEHIISAGLADMVAAAETITTDSEKYVEQLLTL 347
           ++ E L  M+ L+ ++ +G+  +   LE HI + GLA +    +    D + YV+ +L +
Sbjct: 732 DKNEDLGRMYMLVSRILDGLGELKTLLESHIHTQGLAAIERCGDAALNDPKVYVQTILDV 911

Query: 348 FNRFSKLVKEAFQDDPRFLTARDKAYKAVVNDATIFKLELPLKQKGVGLKTQPESKCPEL 407
             +++ LV  AF +D  F+ A DKA    +N+ ++ K+                SK PEL
Sbjct: 912 HKKYNALVLTAFVNDAGFVAALDKACGRFINNNSVTKM------------VNNTSKSPEL 1055

Query: 408 LANYCDMLLRKT 419
           LA YCD+LL+K+
Sbjct: 1056LARYCDLLLKKS 1091
>02365
          Length = 1804

 Score =  153 bits (387), Expect = 2e-37,   Method: Compositional matrix adjust.
 Identities = 134/459 (29%), Positives = 216/459 (47%), Gaps = 24/459 (5%)
 Frame = +1

Query: 346 TLFNRFSKLVKEAFQDDPRFLTARDKAYKAVVNDATIFKLELPLKQKGVGLKTQPESKCP 405
           T+FN F   + E+F +D +F       ++  +N                     P  K P
Sbjct: 523 TVFNHF---LHESFNEDKQFKQMISSGFEHFIN-------------------LNP--KSP 630

Query: 406 ELLANYCDMLLRKTPLSKKLTSXXXXXXXXXXXXXXXXXQNKDVFMRYHKAHLTRRLILD 465
           E L+ + D  L+K    K ++                  Q KDVF RY+K HL RRL+L+
Sbjct: 631 EYLSLFIDDKLKKG--VKGMSEQEIEVVLDKSMVLFRYLQEKDVFERYYKQHLARRLLLN 804

Query: 466 ISADSEIEENMVEWLR-EVGMPADYVNKLARMFQDIKVSEDLNQAFK-EMHKNNKLALPA 523
            S   + E+NM+  L+ E G    + +KL  MF+D+ VS  +N  FK  + +   + L  
Sbjct: 805 KSGSDDSEKNMISKLKTECG--CQFTSKLEGMFKDMTVSSGINDEFKASVQQTQVVNLSG 978

Query: 524 DSVNIKILNAGAWSRSSEKVFVSLPTELEDLIPEVEEFYKKNHSGRKLHWH-HLMSNGI- 581
             + +++L  G W   S    +++P +          FY   HSGR+L    HL S  + 
Sbjct: 979 VELTVRVLTTGYWPTQSATP-INIPVDPRTAFEAFRRFYLAKHSGRQLTLQPHLGSADLH 1155

Query: 582 ITFKNEVG------------------QYDLEVTTFQLAVLFAWNQRPREKISFENLKLAT 623
            +F  +                    ++ L+V+T+Q+ +L  +N R  +K +FE +K  T
Sbjct: 1156ASFFGQKKDDSADSAAASSSKPAGPRKHILQVSTYQMCILLLFNNR--DKWTFEEIKTET 1329

Query: 624 ELPDAELRRTLWSLVAFPKLKRQVLLYDPQVNSPKDFTEGTLFSVNQDFS--LIKNAKVQ 681
           ++PD EL R L SL A  KL ++VL  +P+    K+     +F+VN  F+  LI      
Sbjct: 1330DMPDRELIRALQSL-AVGKLAQRVLHKEPKT---KEIEPDHIFTVNDQFTSKLI------ 1479

Query: 682 KRGKINLIGRLQLTTERMREEENEGIVQLRILRTQEAIIQIMKMRKKISNAQLQTELVEI 741
            R KI ++   +   E  R+E    + + R    + AI++IMK RKK+ +  L TE+ E+
Sbjct: 1480-RVKIQMVASNKGEAEPERKETRNKVDEDRKHEIEAAIVRIMKARKKLQHNVLVTEVTEM 1656

Query: 742 LKNMFLPQKKMIKEQMEWLIEHRYIRRDEADINTFIYMA 780
           LK  FLP   +IK+++E LIE  Y+ R + D   + Y+A
Sbjct: 1657LKPRFLPSPVVIKKRIEGLIEREYLARSQEDRKIYTYVA 1773

 Score = 70.9 bits (172), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 47/168 (27%), Positives = 86/168 (51%)
 Frame = +3

Query: 193 DKLQIYRDNFEKAYLDSTERFYRTQAPSYLQQNGVQNYMKYADAKLKEEEKRALRYLETR 252
           D   +Y ++FEK +L+ +  FYR ++  +L +N    Y+K  +A++ EE +RA  YL+  
Sbjct: 57  DSRTVYEEDFEKPFLEQSAEFYRLESQKFLAENSASVYIKKVEARINEEAERATHYLDKS 236

Query: 253 RECNSVEALMECCVNALVTSFKETILAECQGMIKRNETEKLHLMFSLMDKVPNGIEPMLK 312
            E   V  L E  ++  + +  E   +    M++ N+T+ L  M+ L  +V  G+  M +
Sbjct: 237 TEDPVVRVLEEELISKHMKTIVEMENSGVVHMLENNKTDDLACMYKLFFRVVYGLRTMCQ 416

Query: 313 DLEEHIISAGLADMVAAAETITTDSEKYVEQLLTLFNRFSKLVKEAFQ 360
            + + +   G A ++  AE  + ++  YV+ LL L +RF       FQ
Sbjct: 417 CISQFLREQGRALVIEEAEE-SKNAITYVQSLLDLNDRF*PFPARVFQ 557
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|29789104|ref|NP_062606.1| N-ethylmaleimide sensitive
fusion protein attachment protein beta [Mus musculus]
         (298 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

37486                                                                 161   3e-40
>37486
          Length = 471

 Score =  161 bits (407), Expect = 3e-40,   Method: Compositional matrix adjust.
 Identities = 74/127 (58%), Positives = 101/127 (79%)
 Frame = -2

Query: 166 LKVAAYAAQLEQYQKAIEIYEQVGANTMDNPLLKYSAKDYFFKAALCHFIVDELNAKLAL 225
           LKVA Y+AQLE Y+KAI+IYEQ+G   MDN LLKYSAKD+FF+A +CH  VD +NA+L++
Sbjct: 470 LKVAEYSAQLENYEKAIDIYEQLGMFAMDNSLLKYSAKDHFFRACVCHMCVDLVNAQLSV 291

Query: 226 EKYEEMFPAFTDSRECXXXXXXXEAHEEQNSEAYTEAVKEFDSISRLDQWLTTMLLRIKK 285
           +KYEEMFPAFTDSREC       +A EE+N++ +TEA++++DSISRLD+ +T M L++KK
Sbjct: 290 QKYEEMFPAFTDSRECKLVKSLLKACEEENADDFTEALRQYDSISRLDKNVTAMFLKVKK 111

Query: 286 SIQGDGE 292
            +  + E
Sbjct: 110 QLNAEPE 90
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|82891122|ref|XP_359308.2| PREDICTED: similar to
Glutathione S-transferase Yb-3 (Chain 4) (GST Yb3) (GST class-mu 3)
isoform 2 [Mus musculus]
         (233 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

35754                                                                 160   3e-40
02955                                                                  49   2e-06
06833                                                                  39   0.003
23210                                                                  32   0.16 
10621                                                                  31   0.44 
18621                                                                  29   2.0  
>35754
          Length = 581

 Score =  160 bits (406), Expect = 3e-40,   Method: Compositional matrix adjust.
 Identities = 83/185 (44%), Positives = 115/185 (62%), Gaps = 5/185 (2%)
 Frame = -2

Query: 51  GDAPDYDQSQWLNEKFKLGLDFPNLPYLIDGSHKITQSNAILRYLGRKHNLCGETEEERI 110
           GDAPD+ +  WL  K  LGLDFPNLPY IDG  K+TQSNAILRY+ RKHNL GET  E  
Sbjct: 553 GDAPDFSRDAWLKVKSSLGLDFPNLPYYIDGDIKLTQSNAILRYIARKHNLMGETPLESA 374

Query: 111 RVDILENQLMDNRMVLARLCYNADF----EKLKPGYLEQLPGMMRLYSEFLGKRPWFAGD 166
           RV+++    MD R  + R+ YN  +    E+ KP   E L G    ++++L  + WFAGD
Sbjct: 373 RVEMMLENAMDFRNGVVRMVYNPKYTDLLEEYKPKVKETLAG----FNKYLADKKWFAGD 206

Query: 167 KITFVDFIAYDVLERNQV-FEAKCLDAFPNLKDFIARFEGLKKISDYMKTSRFLPRPMFT 225
           K+T  DF  Y++L+++++   A  L  +P L  F+A FE L  I  YM + +F+ RP+  
Sbjct: 205 KVTVADFHMYELLDQHRLMIGADVLKDYPKLTAFMAAFEALPAIKKYMASDKFMKRPVNN 26

Query: 226 KMATW 230
           K+A +
Sbjct: 25  KVAAF 11
>02955
          Length = 1322

 Score = 48.9 bits (115), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 48/193 (24%), Positives = 80/193 (41%), Gaps = 11/193 (5%)
 Frame = +1

Query: 32  IRLFLEYTDSSYEEKRYTMGD-APDYDQSQWLNEKFKLGLDFPNLPYLIDGSHKITQSNA 90
           +RL        +E+KR    D  PD D         K    +  +PY+I    K  QS A
Sbjct: 67  LRLLFRAAGVQFEDKRIERADWGPDSDA--------KKATPYGQVPYVIYQGKKRGQSIA 222

Query: 91  ILRYLGRKHNLCGETEEERIRVDILENQLMDNRMVLARLCYNADFEKLKPG--------- 141
           +  Y  RK    G+T+E+  + + + + L+D+ +V     +  + +  K           
Sbjct: 223 MGTYFARKFGFYGKTDEDAWKQEEIMH-LIDDLIVGPNRAWFLEQDPQKKAERTRELTEV 399

Query: 142 -YLEQLPGMMRLYSEFLGKRPWFAGDKITFVDFIAYDVLERNQVFEAKCLDAFPNLKDFI 200
            Y   L    RL +E  G + +  GD +T  D   +DVLE     + + L +FP  +   
Sbjct: 400 QYPRYLSSFERLLAEN-GDQGYSVGDSVTLADLCLHDVLETVLGVDPRALXSFPLQRKLR 576

Query: 201 ARFEGLKKISDYM 213
           A  E L  + +Y+
Sbjct: 577 ANVENLPALKEYL 615
>06833
          Length = 882

 Score = 38.5 bits (88), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 37/160 (23%), Positives = 66/160 (41%), Gaps = 13/160 (8%)
 Frame = +3

Query: 33  RLFLEYTDSSYEEKRYTMGDAPDYDQSQWLNEKFKLGLDFPNLPYL--IDGS----HKIT 86
           RL L      Y++ R+        D+ +W  + +K    F   P+L   D       KI 
Sbjct: 144 RLLLALAGQDYQDVRF--------DREEWA-QTYKAEAPFGQGPFLAFTDSKTKKLKKIG 296

Query: 87  QSNAILRYLGRKHNLCGETEEERIRVDILENQLMDNRMVLARLCYNADFEKLKPGYL--- 143
           QS+AI  +L R+  L G + ++   +D + +   D  +   ++    D +K    +    
Sbjct: 297 QSSAIACFLAREFGLYGSSNQDGAVIDQVVHLYRDMVVAWQKVMLTEDADKKTEAHKKLM 476

Query: 144 -EQLPGMMRLYSEFL---GKRPWFAGDKITFVDFIAYDVL 179
            E+ P     +++ L      P+F G+ IT  D   YD +
Sbjct: 477 EEEFPKFFGHFNKLLEENSDSPFFVGNSITLADVYXYDXI 596
>23210
          Length = 944

 Score = 32.3 bits (72), Expect = 0.16,   Method: Compositional matrix adjust.
 Identities = 23/72 (31%), Positives = 36/72 (50%), Gaps = 2/72 (2%)
 Frame = -1

Query: 71  DFPN--LPYLIDGSHKITQSNAILRYLGRKHNLCGETEEERIRVDILENQLMDNRMVLAR 128
           D PN   P+L     +  QS AI  +L R++NL G++  + IR+D +     D    L +
Sbjct: 686 DAPNGQAPFLEYKGKRYGQSIAIANFLARENNLYGKSNLDAIRIDEVVQLTADVWAALGK 507

Query: 129 LCYNADFEKLKP 140
             +  D EK +P
Sbjct: 506 AHFQTD-EK*RP 474
>10621
          Length = 1304

 Score = 30.8 bits (68), Expect = 0.44,   Method: Compositional matrix adjust.
 Identities = 24/94 (25%), Positives = 46/94 (48%), Gaps = 6/94 (6%)
 Frame = +2

Query: 85  ITQSNAILRYLGRKHNLCGETEEERIRV----DILENQLMDNRMVLARLCYN-ADFEKLK 139
           +++SNAI +Y+G K  L GET E   +V    D  +N+++ +       C     F K +
Sbjct: 209 LSESNAIAQYVGNKK-LQGETAEAAAQVSQWIDFADNEILPSVCTWVFPCLGITQFNKQE 385

Query: 140 PGYLE-QLPGMMRLYSEFLGKRPWFAGDKITFVD 172
               + Q+   + + +++L  R +  G+ +T  D
Sbjct: 386 TERAKAQVTKALTVLNDYLLTRTYLVGESVTQAD 487
>18621
          Length = 515

 Score = 28.9 bits (63), Expect = 2.0,   Method: Compositional matrix adjust.
 Identities = 11/29 (37%), Positives = 17/29 (58%)
 Frame = -1

Query: 158 GKRPWFAGDKITFVDFIAYDVLERNQVFE 186
           G  P+F+GDK  F D++ +   ER  + E
Sbjct: 155 GSHPYFSGDKPGFSDYMTWPWFERMYMLE 69
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|12963847|ref|NP_076343.1| ADP-ribosylation factor
GTPase activating protein 2 [Mus musculus]
         (520 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

02435                                                                 162   4e-40
02351                                                                  72   4e-13
26051                                                                  43   3e-04
21135                                                                  39   0.007
05134                                                                  28   7.6  
>02435
          Length = 1890

 Score =  162 bits (409), Expect = 4e-40,   Method: Compositional matrix adjust.
 Identities = 121/332 (36%), Positives = 165/332 (49%), Gaps = 25/332 (7%)
 Frame = +2

Query: 38  SITYGVFLCIDCSGVHR-SLGVHLSFIRS----------TELDS---NWSWLQLRCMQVG 83
           SI Y  FLC D    H  +L  H+    S           +L S   +WSWLQLR MQ+G
Sbjct: 362 SIWY--FLCRDVRKGHEIALKYHIILCTS*STQCSLHVGHQL*SKQ*HWSWLQLRAMQIG 535

Query: 84  GNANATAFFRQHGCMANDANTKYTSRAAQMYREKIRQLGSAALTRHGTDLWIDSMNSAPS 143
           GN+NA  FF +HGC   DA  KY SRAA+MYR+K+      A+  HGT L ID+ ++ P+
Sbjct: 536 GNSNARIFFNEHGCTTTDAQQKYNSRAARMYRDKLLSQAQHAMRLHGTKLHIDA-HAEPT 712

Query: 144 HSPEKKDSDFFTEHTQAPAW-DTAATDPSGTQQPALPSESSSLAQPEQGPNTD-LLGTSP 201
              E K+ DFF+EHT+     D  A       QP      +   +P+ GP+ +  L TSP
Sbjct: 713 SPGESKEVDFFSEHTKDEGREDLNAEQKLSAPQPVKNGSVNKTQEPDVGPSVEAALSTSP 892

Query: 202 -QAS--LELKSSIIXXXXXXXXXXXXXXXXXXXXQKVSNQSFTEIERQAQVAEKLRXXXX 258
            QA+  LE + ++I                    Q+V   +FTEIE +AQ A+K R    
Sbjct: 893 TQAASQLEPRKTLI----GAKKAPANKKGKGLGAQRV-KANFTEIENRAQQADKEREEFA 1057

Query: 259 XXXXXXXXXS------MVASMRLAYQELQIDRKKEEKKLQNLEGKKREQAERLGMGXXXX 312
                    +       +ASMRLAYQ++ + RKK+E K++  + KK  Q ERLGMG    
Sbjct: 1058KNQAIQEAKTQEEQDKQMASMRLAYQDMSVQRKKQEDKIKASDPKKAAQLERLGMGFISN 1237

Query: 313 XXXXXXXXXEMQMIEQETPLSAKSSRSQLDLF 344
                    +MQ I+QE P  ++S  S  DLF
Sbjct: 1238KGISHSAVSDMQTIQQEAP--SRSRNSDRDLF 1327
>02351
          Length = 939

 Score = 72.4 bits (176), Expect = 4e-13,   Method: Compositional matrix adjust.
 Identities = 38/93 (40%), Positives = 52/93 (55%)
 Frame = +3

Query: 17  LRAIPTNKACFDCGAKSPSWASITYGVFLCIDCSGVHRSLGVHLSFIRSTELDSNWSWLQ 76
           +R    N  C DCG  SPSWASI  G  +CI+C GVHR++G H+S +RS +LD +W    
Sbjct: 6   IRTTRGNTICVDCGTPSPSWASINLGAVMCIECCGVHRNIGTHISRVRSLDLD-DWPPEV 182

Query: 77  LRCMQVGGNANATAFFRQHGCMANDANTKYTSR 109
            + M   GN  A + +        +ANTK  S+
Sbjct: 183 TKVMTSIGNYVANSVW--------EANTKGRSK 257
>26051
          Length = 425

 Score = 43.1 bits (100), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 35/107 (32%), Positives = 48/107 (44%), Gaps = 12/107 (11%)
 Frame = +1

Query: 424 FAGAKAISSDMFFGREVDSEYEARSRLQQLXXXXXXXXXDLFGDMDGAHGGG--TVSLGN 481
           F  +K   SD +F  +  S  +  + L +          D F   DG  GGG    S G 
Sbjct: 1   FGNSKGFGSDQYFASD-QSSADNSANLNRFQGSRAISSSDYF--NDGTQGGGLSNRSSGG 171

Query: 482 VLPTA---------DIAQ-FKQGVKSVAGKMAVLANGVMNSLQDRYG 518
              TA         D+ +  + GV  VAG+++ LAN VM SLQD+YG
Sbjct: 172 GYSTAVNFNAPDLDDVKESVRHGVHKVAGRLSNLANDVMTSLQDKYG 312
>21135
          Length = 376

 Score = 38.5 bits (88), Expect = 0.007,   Method: Composition-based stats.
 Identities = 27/78 (34%), Positives = 38/78 (48%), Gaps = 4/78 (5%)
 Frame = +3

Query: 443 EYEARSRLQQLXXXXXXXXXDLFGDMDGAHGGGTVSLGNVLPTADIAQFKQGVKS----V 498
           +YE R  L ++         D+FG      G    S      T D+   K GVK     V
Sbjct: 3   DYEVRQNLNRMEGRTGISSDDVFGT-----GQSRSSSNYGSSTPDLQDIKDGVKQGITKV 167

Query: 499 AGKMAVLANGVMNSLQDR 516
           AG+++ +ANGV++SLQDR
Sbjct: 168 AGRLSNIANGVVSSLQDR 221
>05134
          Length = 1402

 Score = 28.5 bits (62), Expect = 7.6,   Method: Compositional matrix adjust.
 Identities = 12/33 (36%), Positives = 17/33 (51%)
 Frame = +2

Query: 42   GVFLCIDCSGVHRSLGVHLSFIRSTELDSNWSW 74
            G +LC  C+G HR  G+H S +        W+W
Sbjct: 1130 GGYLCGVCAGWHRQEGLHHSVLIYQAYSYFWNW 1228
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6754816|ref|NP_035021.1| septin 2 [Mus musculus]
         (361 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

14132                                                                 161   4e-40
34156                                                                 142   2e-34
22078                                                                  92   5e-19
14677                                                                  74   4e-17
29788                                                                  75   6e-14
06491                                                                  32   0.43 
38040                                                                  30   1.5  
38061                                                                  28   4.3  
08459                                                                  28   6.3  
02679                                                                  28   8.1  
>14132
          Length = 422

 Score =  161 bits (407), Expect = 4e-40,   Method: Compositional matrix adjust.
 Identities = 77/142 (54%), Positives = 104/142 (73%), Gaps = 1/142 (0%)
 Frame = -2

Query: 105 YGDAINCRDCFKTIISYIDEQFERYLHDESGLNRRHIIDNRVHCCFYFISPFGHGLKPLD 164
           +GDA++  +C++ I  YID ++E YL+ ES +NR  + D RVHCC YFI+P GHGLKPLD
Sbjct: 421 FGDAVDNSNCWQPITDYIDSKYEEYLNAESRVNRTVMPDTRVHCCLYFIAPTGHGLKPLD 242

Query: 165 VAFMKAIHNKVNIVPVIAKADTLTLKERERLKKRILDEIEEHSIKIYHLPDAESDEDEDF 224
           V FMK +H+KVNI+P++AKADTLT  E    KK IL+EI +H IKIY  PD   D++E+ 
Sbjct: 241 VEFMKRLHDKVNIIPLVAKADTLTPDECREFKKTILNEIAQHKIKIYEFPDC--DDEEEM 68

Query: 225 KEQTRL-LKASIPFSVVGSNQL 245
           K Q RL +   +PF+VVGSN++
Sbjct: 67  KIQKRLRVSDRVPFAVVGSNRV 2
>34156
          Length = 348

 Score =  142 bits (359), Expect = 2e-34,   Method: Compositional matrix adjust.
 Identities = 73/95 (76%), Positives = 80/95 (84%), Gaps = 1/95 (1%)
 Frame = -1

Query: 9   FINPETPGYVGFANL-PNQVHRKSVKKGFEFTLMVVGESGLGKSTLINSLFLTDLYPERI 67
           F  P      G   + P QVHRKSVKKGFEFTLMVVGESGLGKSTL+NSLFLTDLYPER 
Sbjct: 285 FCQPGAGRVRGVCQIYPTQVHRKSVKKGFEFTLMVVGESGLGKSTLVNSLFLTDLYPERH 106

Query: 68  IPGAAEKIERTVQIEASTVEIEERGVKLRLTVVDT 102
           IP A+EKI++TV+I+ASTVEIEERGVKLRLTVVDT
Sbjct: 105 IPSASEKIQQTVKIDASTVEIEERGVKLRLTVVDT 1
>22078
          Length = 417

 Score = 91.7 bits (226), Expect = 5e-19,   Method: Compositional matrix adjust.
 Identities = 45/91 (49%), Positives = 60/91 (65%), Gaps = 15/91 (16%)
 Frame = +3

Query: 254 RGRLYPWGVVEVENPEHNDFLKLRTMLI-THMQDLQEVTQDLHYENFRS----------- 301
           RGR YPWG+VEV+N  H DF++LR MLI THMQDL++VT D+HYENFRS           
Sbjct: 3   RGRAYPWGIVEVDNXSHCDFIRLRQMLISTHMQDLKDVTSDVHYENFRSSFIQQSLAAQH 182

Query: 302 ---ERLKRGGRKVENEDMNKDQILLEKEAEL 329
               +LKR  +  E + M+ D +L +K+AE+
Sbjct: 183 RERSKLKRDSKPCEEDGMDTDTLLQQKDAEI 275
>14677
          Length = 378

 Score = 74.3 bits (181), Expect(2) = 4e-17,   Method: Compositional matrix adjust.
 Identities = 35/76 (46%), Positives = 50/76 (65%), Gaps = 2/76 (2%)
 Frame = -1

Query: 79  VQIEASTVEIEERGVKLRLTVVDTPGYGDAINCRDCFKTIISYIDEQFERYLHDESGLNR 138
           V+++A T ++ E+ V+L+LT VDT G+GD IN  D +K I+ YID QF+ YL +E  + R
Sbjct: 228 VKLKAHTYDLTEKNVRLKLTTVDTTGFGDQINKADSWKPIVDYIDAQFDAYLQEELKIKR 49

Query: 139 --RHIIDNRVHCCFYF 152
                 D+RVH C YF
Sbjct: 48  MLHSYHDSRVHACLYF 1

 Score = 30.8 bits (68), Expect(2) = 4e-17,   Method: Compositional matrix adjust.
 Identities = 13/24 (54%), Positives = 20/24 (83%)
 Frame = -3

Query: 39  TLMVVGESGLGKSTLINSLFLTDL 62
           T  V+GE+G+GKSTL+++LF T+ 
Sbjct: 334 TFFVLGETGIGKSTLMDTLFNTNF 263
>29788
          Length = 687

 Score = 74.7 bits (182), Expect = 6e-14,   Method: Compositional matrix adjust.
 Identities = 33/47 (70%), Positives = 40/47 (85%), Gaps = 1/47 (2%)
 Frame = +3

Query: 259 PWGVVEVENPEHNDFLKLRTMLI-THMQDLQEVTQDLHYENFRSERL 304
           PWG+VEVEN EHNDF+ LR MLI THMQDL++VT ++HYENFR  +L
Sbjct: 3   PWGIVEVENLEHNDFIALRNMLIRTHMQDLKDVTNNVHYENFRYNKL 143
>06491
          Length = 1083

 Score = 32.0 bits (71), Expect = 0.43,   Method: Compositional matrix adjust.
 Identities = 17/75 (22%), Positives = 37/75 (49%), Gaps = 4/75 (5%)
 Frame = -3

Query: 128 RYLHDESGLNRRHIIDNRVHCCFYFI----SPFGHGLKPLDVAFMKAIHNKVNIVPVIAK 183
           R + DE  + ++  +D  +H C  ++    +PF     P+  A ++ I  ++ +VP +A+
Sbjct: 961 RRMRDEGKITKQEFLDTNMHRCPKYLEEYKAPFADPNSPVRKAGLELISAELVLVPCVAQ 782

Query: 184 ADTLTLKERERLKKR 198
               +  E+E +  R
Sbjct: 781 QAWKSKMEKEGIDDR 737
>38040
          Length = 374

 Score = 30.0 bits (66), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 17/54 (31%), Positives = 25/54 (46%)
 Frame = -2

Query: 239 VVGSNQLIEAKGKKVRGRLYPWGVVEVENPEHNDFLKLRTMLITHMQDLQEVTQ 292
           V+G+   +E +G+ VRG    WG + V        + L   LITH  DL    +
Sbjct: 307 VLGAR*TLEVRGRPVRGYRVNWGALSVTVVHAT--VSLEQFLITHWSDLSNTVE 152
>38061
          Length = 206

 Score = 28.5 bits (62), Expect = 4.3,   Method: Composition-based stats.
 Identities = 11/30 (36%), Positives = 18/30 (60%)
 Frame = +3

Query: 231 LKASIPFSVVGSNQLIEAKGKKVRGRLYPW 260
           + + +PF+VVGSN  ++   K V+ R   W
Sbjct: 117 MNSHLPFAVVGSNDEVKIGNKMVKARQGSW 206
>08459
          Length = 1344

 Score = 28.1 bits (61), Expect = 6.3,   Method: Compositional matrix adjust.
 Identities = 25/98 (25%), Positives = 42/98 (42%)
 Frame = -1

Query: 158  HGLKPLDVAFMKAIHNKVNIVPVIAKADTLTLKERERLKKRILDEIEEHSIKIYHLPDAE 217
            HGL   DV     +  K+N++PVI + +   L +       +   ++  ++   HLP   
Sbjct: 1041 HGLHKADVVLKLHVGVKLNVLPVIERLNHPRLGQHPH--DLLPVRVQHGNVHTAHLP--- 877

Query: 218  SDEDEDFKEQTRLLKASIPFSVVGSNQLIEAKGKKVRG 255
                + FK  T  + A     ++    L+EA GK  RG
Sbjct: 876  ----KRFKHFTHNVLARS*LGLLAVAVLVEAFGKPARG 775
>02679
          Length = 836

 Score = 27.7 bits (60), Expect = 8.1,   Method: Compositional matrix adjust.
 Identities = 14/49 (28%), Positives = 24/49 (48%)
 Frame = +3

Query: 115 FKTIISYIDEQFERYLHDESGLNRRHIIDNRVHCCFYFISPFGHGLKPL 163
           F+T+ ++I++   R  H+E   + +HI     H  F   +PF     PL
Sbjct: 147 FRTLCNHINKVLVRSAHNEQRRSCKHISHTHTHSVFSHCNPFS*LKSPL 293
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|112293266|ref|NP_032326.3| heat shock protein 4 [Mus
musculus]
         (842 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

21024                                                                 115   5e-40
18301                                                                 125   7e-29
37715                                                                  82   2e-22
27378                                                                  96   4e-20
20979                                                                  93   4e-19
03996                                                                  86   8e-17
12271                                                                  81   2e-15
13300                                                                  74   4e-13
30255                                                                  62   1e-09
09881                                                                  62   1e-09
19659                                                                  53   5e-07
31218                                                                  46   6e-05
13684                                                                  45   1e-04
>21024
          Length = 3220

 Score =  115 bits (287), Expect(2) = 5e-40,   Method: Compositional matrix adjust.
 Identities = 83/273 (30%), Positives = 137/273 (50%), Gaps = 3/273 (1%)
 Frame = +3

Query: 3   VVGIDLGFQSCYVAVARAGGIETIANEYSDRCTPACVSFGPKNRSI-GAAAKSQVISNAK 61
           V+GIDLG  +  VA+      + + N    R TP+ ++F      I G  AK Q ++NA+
Sbjct: 252 VIGIDLGTTNSCVALMEGKQAKVLENSEGSRTTPSVIAFTKDGERISGMPAKRQAVTNAE 431

Query: 62  NTVQGFKRFHGRAFSDPFVEAEKSNLAYDIVQLPTGLTGIKVTYMEEERNFTTEQVTAML 121
           NT+   KR  GR F DP V+ +  N++Y IV+   G   ++     + + ++  QV A +
Sbjct: 432 NTLSATKRLIGRRFEDPEVQKDMKNVSYKIVKASNGDAWVEA----QGKMYSPSQVGAFV 599

Query: 122 LSKLKETAESVLKKPVVDCVVSVPSFYTDAERRSVMDATQIAGLNCLRLMNETTAVALAY 181
           L K+KETAES L   V + VV+VP+++ D++R++  DA QI+GL C+     T + +  +
Sbjct: 600 LMKMKETAESYLGSKVNNAVVTVPAYFNDSQRQATKDAGQISGLKCVACDQRTHSCSSCF 779

Query: 182 GIYKQDLPALEEKPRNVVFVDMGHSAYQVSVCAFNKGK--LKVLATAFDTTLGGRKFDEV 239
             +     +L+ K    +    G    +++  ++   +  LK        +   R FD  
Sbjct: 780 MAW----TSLKIK**RCLI*AEG----RLTSLSWRSRRECLKSNQPTETHSWEERTFDNY 935

Query: 240 LVNHFCEEFGKKYKLDIKSKIRALLRLSQECEK 272
           +VN    EF K+  LDI     A+ RL +  EK
Sbjct: 936 MVNFLASEFKKEQGLDITKDPMAVQRLREAAEK 1034

 Score = 68.9 bits (167), Expect(2) = 5e-40,   Method: Compositional matrix adjust.
 Identities = 35/104 (33%), Positives = 59/104 (56%)
 Frame = +1

Query: 301  MNRGKFLEMCDDLLARVEPPLRSVLEQSKLKKEDIYAVEIVGGATRIPAVKEKISKFFGK 360
            ++R KF  + + L+ R   P +  L+ +++KK DI  V +VGG +R+P V+  +   FG+
Sbjct: 1126 LSRSKFESLVESLVKRTVGPCQKALQDAEVKKSDIGEVILVGGMSRMPKVQSTVQDLFGR 1305

Query: 361  ELSTTLNADEAVTRGCALQCAILSPAFKVREFSITDVVPYPISL 404
              S ++N DEAV  G A+Q  +L  A  V +  + DV P  + +
Sbjct: 1306 TPSKSVNPDEAVAIGAAIQGGVL--AGDVTDVLLLDVTPLSLGI 1431
>18301
          Length = 752

 Score =  125 bits (314), Expect = 7e-29,   Method: Compositional matrix adjust.
 Identities = 73/152 (48%), Positives = 95/152 (62%), Gaps = 4/152 (2%)
 Frame = +3

Query: 374 RGCALQCAILSPAFKVREFSITDVVPYPISLRW---NSPAEEGLSDCEVFPKNHAAPFSK 430
           RGCALQCAILSP F+VR+FS+TD   Y I+L W   N   E+  S  +V P+ H  P SK
Sbjct: 3   RGCALQCAILSPTFRVRDFSVTDCQTYTITLTWVPQNQMDED--SRVDVLPQFHHIPASK 176

Query: 431 VLTFYRKEPFTLEAYYSSPQDLPYPDPAIAQFSVQKVTPQSDGXXXXXXXXXRVNVHGIF 490
           +LTFYRKEPF L A Y+ P ++P+P   I +F +  VT Q++G         R+N + IF
Sbjct: 177 MLTFYRKEPFVLNAVYTQPANVPFPSAQIGEFKITNVTAQANGESSKVKVKVRINGNSIF 356

Query: 491 SVSSAAL-VEVHKSEESEEPMETDQNAKEEEK 521
           SVS+A +  +V   EE EEPM+ D    EEEK
Sbjct: 357 SVSAATMYEKVEGEEEKEEPMDVD---GEEEK 443
>37715
          Length = 468

 Score = 81.6 bits (200), Expect(2) = 2e-22,   Method: Compositional matrix adjust.
 Identities = 35/78 (44%), Positives = 59/78 (75%)
 Frame = -2

Query: 110 RNFTTEQVTAMLLSKLKETAESVLKKPVVDCVVSVPSFYTDAERRSVMDATQIAGLNCLR 169
           + F  E+++AM+L K+++ AE+ L K + + VV+VP+++ DA+R++  DA  IAGLN +R
Sbjct: 398 KTFAPEEISAMVLGKMRDIAEAYLGKKIDNAVVTVPAYFNDAQRQATKDAGTIAGLNVMR 219

Query: 170 LMNETTAVALAYGIYKQD 187
           ++NE TA A+AYG+ K+D
Sbjct: 218 IINEPTAAAIAYGLDKRD 165

 Score = 43.1 bits (100), Expect(2) = 2e-22,   Method: Composition-based stats.
 Identities = 18/48 (37%), Positives = 30/48 (62%)
 Frame = -1

Query: 197 NVVFVDMGHSAYQVSVCAFNKGKLKVLATAFDTTLGGRKFDEVLVNHF 244
           N++  D+G   + VS+   + G  +V+AT  DT LGG  FD+ +++HF
Sbjct: 156 NILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMDHF 13
>27378
          Length = 410

 Score = 96.3 bits (238), Expect = 4e-20,   Method: Compositional matrix adjust.
 Identities = 50/137 (36%), Positives = 83/137 (60%), Gaps = 1/137 (0%)
 Frame = -1

Query: 247 EFGKKYKLDIKSKIRALLRLSQECEKLKKLMSANASDLPLSIECFMNDIDVSGTMNRGKF 306
           EF +KYK D++S  RAL RL    E+ K+ +S+ +++  + ++      D    ++R +F
Sbjct: 410 EFKRKYKKDLRSNPRALRRLRTAAERAKRTLSS-STEATIEVDALFEGHDFYTKISRARF 234

Query: 307 LEMCDDLLARVEPPLRSVLEQSKLKKEDIYAVEIVGGATRIPAVKEKISKFF-GKELSTT 365
            E+C DL  +   P+   L  +K+ K+ I+ + +VGG+TRIP V+  + +FF GK L+ +
Sbjct: 233 EELCADLFRQTLAPVEKALNDAKMDKQMIHDIVLVGGSTRIPKVQNLLQQFFGGKSLNLS 54

Query: 366 LNADEAVTRGCALQCAI 382
           +N DEAV  G A+Q AI
Sbjct: 53  INPDEAVAYGAAVQAAI 3
>20979
          Length = 976

 Score = 93.2 bits (230), Expect = 4e-19,   Method: Compositional matrix adjust.
 Identities = 54/154 (35%), Positives = 89/154 (57%), Gaps = 3/154 (1%)
 Frame = +1

Query: 240 LVNHFCEEFG--KKYKLDIKSKIRALLRLSQECEKLKKLMSANASDLPLSIECFMNDIDV 297
           L +H  + F   KK    ++   RA+ +L +E E++KK++SAN SD    +E  +   D 
Sbjct: 91  LRDHLAKVFNGQKKRSFKLEDNPRAMAKLLKEAERVKKVLSAN-SDHKAQVEGLVEGEDF 267

Query: 298 SGTMNRGKFLEMCDDLLARVEPPLRSVLEQSKLKKEDIYAVEIVGGATRIPAVKEKISKF 357
           +  ++R  +LE+  DLLARV  P+   L+ S++   +I  + ++GG +R+P V+E++ KF
Sbjct: 268 AAKVSREDYLELIKDLLARVTKPMEDALKVSEITMPEITEIILMGGGSRVPRVQEELLKF 447

Query: 358 FGK-ELSTTLNADEAVTRGCALQCAILSPAFKVR 390
            GK +L  ++N DEA   G   Q A L   FKV+
Sbjct: 448 SGKSDLGKSINTDEAAALGAVYQAAYLGKGFKVK 549
>03996
          Length = 1105

 Score = 85.5 bits (210), Expect = 8e-17,   Method: Compositional matrix adjust.
 Identities = 51/156 (32%), Positives = 80/156 (51%), Gaps = 9/156 (5%)
 Frame = -2

Query: 307  LEMCDDLLARVEPPLRSVLEQSKLKKEDIYAVEIVGGATRIPAVKEKISKFFGK-ELSTT 365
            LE+  DLLARV  P+   L+ S++   +I  + ++GG +R+P V+E++ KF GK +L  +
Sbjct: 1059 LELIKDLLARVTKPMEDALKVSEITMPEITEIILMGGGSRVPRVQEELLKFSGKSDLGKS 880

Query: 366  LNADEAVTRGCALQCAILSPAFKVREFSITDVVPYPISLRWNSPAEEGLSDCE------- 418
            +N DEA   G   Q A L   FKV+ F + D   YPI++ +     E  S          
Sbjct: 879  INTDEAAALGAVYQAAYLGKGFKVKTFHVRDANIYPINVEFEKQKSEEDSATSARTIKRT 700

Query: 419  VFPKNHAAPFSKVLTFYRK-EPFTLEAYYSSPQDLP 453
            +F + +  P  KV+TF +  + F  E  Y     +P
Sbjct: 699  LFGRMNPYPQRKVMTFNKHFKDFNFEVRYGDLDFIP 592
>12271
          Length = 1762

 Score = 80.9 bits (198), Expect = 2e-15,   Method: Compositional matrix adjust.
 Identities = 50/161 (31%), Positives = 82/161 (50%), Gaps = 14/161 (8%)
 Frame = +2

Query: 296 DVSGTMNRGKFLEMCDDLLARVEPPLRSVLEQSKLKKEDIYAVEIVGGATRIPAVKEKIS 355
           D S  + R K+L +  DLL RV  P++ VL  S++   +I  + ++GG +R+P + E + 
Sbjct: 41  DFSCKVTRDKYLHLIQDLLDRVTLPVQQVLTASQITWAEITEIILMGGGSRLPKIHEILL 220

Query: 356 KFFG-KELSTTLNADEAVTRGCALQCAILSPAFKVREFSITDVVPYPISLRW--NSPAEE 412
            + G KEL  +LN DEA   G   Q A L+  FKV+ F + D   +PI++ +   +  EE
Sbjct: 221 DYSGKKELGKSLNTDEAGALGAVYQAAYLAKGFKVKTFHVRDANLFPINVEFAKQTTNEE 400

Query: 413 GLSDCEV-----------FPKNHAAPFSKVLTFYRKEPFTL 442
           G  + +V           FP+  + P +++    R  P T 
Sbjct: 401 GSEEVKVIQRTLFGRSHYFPRRRS*PSTRITX--RTSPLTF 517
>13300
          Length = 453

 Score = 73.6 bits (179), Expect = 4e-13,   Method: Compositional matrix adjust.
 Identities = 47/152 (30%), Positives = 79/152 (51%), Gaps = 14/152 (9%)
 Frame = +3

Query: 152 ERRSVMDATQIAGLNCLRLMNETTAVALAYGIYKQDLPALEEKPRNVVFVDMGHSAYQVS 211
           ERR++M A    G+N L+LM ++ AVAL YG++++         +  +F DMG ++   +
Sbjct: 3   ERRAIMTAADXVGINVLQLMTDSAAVALNYGVFRR--KNFNTTAQYYMFYDMGATSTVAT 176

Query: 212 VCAFNKGKLK------------VLATAFDTTLGGRKFDEVLVNHFCEEFG--KKYKLDIK 257
           V ++   K+K            +    FD TLGG +    L +H  + F   KK    ++
Sbjct: 177 VVSYQVVKVKEGTRVESNPQLTIKGVGFDRTLGGLEMTLRLRDHLAKVFNGQKKRSFKLE 356

Query: 258 SKIRALLRLSQECEKLKKLMSANASDLPLSIE 289
              RA+ +L +E E++KK++SAN SD    +E
Sbjct: 357 DNPRAMAKLLKEAERVKKVLSAN-SDHKAQVE 449
>30255
          Length = 1761

 Score = 61.6 bits (148), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 45/170 (26%), Positives = 78/170 (45%), Gaps = 6/170 (3%)
 Frame = -1

Query: 332  KEDIYAVEIVGGATRIPAVKEKISKFF-GKELSTTLNADEAVTRGCALQCAIL--SPAFK 388
            K  I+ + +VGG+TRIP +++ +  FF GKEL  ++N DEAV  G  +Q AIL    + +
Sbjct: 1644 KPGIHEIVLVGGSTRIPKIQKLLQDFFNGKELCKSINPDEAVAYGACVQAAILHGDKSEE 1465

Query: 389  VREFSITDVVPYPISLRWNSPAEEGLSDCEVFPKNHAAPFSKVLTFYR---KEPFTLEAY 445
            V++  + DV P  + +         L       +N   P  +  TF      +P  L   
Sbjct: 1464 VQDLLLLDVAPLSMGIETAGGVMTAL-----IKRNTTIPTKQTQTFTTYSDNQPGVLIQV 1300

Query: 446  YSSPQDLPYPDPAIAQFSVQKVTPQSDGXXXXXXXXXRVNVHGIFSVSSA 495
            Y   + +   +  + +F +  + P   G          ++ +GI +VS+A
Sbjct: 1299 YEGERAMTRDNNLLGKFELTGIPPAPRGVPQIEVTFD-IDANGILNVSAA 1153
>09881
          Length = 600

 Score = 61.6 bits (148), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 32/81 (39%), Positives = 44/81 (54%)
 Frame = +3

Query: 1   MSVVGIDLGFQSCYVAVARAGGIETIANEYSDRCTPACVSFGPKNRSIGAAAKSQVISNA 60
           M+  G+ LG  S  +AV + G     AN+  DR TP  V+F   +  +GA+AK  ++SN 
Sbjct: 180 MAAYGVHLGTCSACLAVYKDGKTSVAANDAGDRSTPCVVAFTACDAEVGASAKQGIVSNV 359

Query: 61  KNTVQGFKRFHGRAFSDPFVE 81
           KNTV   KR  G  F DP  +
Sbjct: 360 KNTVCNVKRILGLTFEDPVTQ 422

 Score = 40.4 bits (93), Expect = 0.003,   Method: Composition-based stats.
 Identities = 21/49 (42%), Positives = 31/49 (63%)
 Frame = +2

Query: 135 KPVVDCVVSVPSFYTDAERRSVMDATQIAGLNCLRLMNETTAVALAYGI 183
           K + D V++VPS ++D +R +   A   AG   LRL+NE +A ALAY +
Sbjct: 5   KGIQDAVLAVPSDFSDKQRAAASAAASKAGFKVLRLINECSAAALAYDL 151
>19659
          Length = 1520

 Score = 53.1 bits (126), Expect = 5e-07,   Method: Compositional matrix adjust.
 Identities = 25/74 (33%), Positives = 43/74 (58%)
 Frame = -1

Query: 713  KVISSFKNKEDQYEHLDAADVTKVEKSTNEAMEWMNSKLNLQNKQSLTVDPVVKTKEIEA 772
            +V+  +   E++Y HLD +DV KV+K  ++ M W   K+  Q++     +PV+   ++ A
Sbjct: 1406 QVLDQYAAGEEKYAHLDKSDVEKVQKCLDDKMAWWGPKMEAQSRIKPYDNPVLLVSQVMA 1227

Query: 773  KIKELTSICSPIIS 786
            + K L S C PII+
Sbjct: 1226 EKKVLESTCHPIIN 1185
>31218
          Length = 322

 Score = 46.2 bits (108), Expect = 6e-05,   Method: Composition-based stats.
 Identities = 31/101 (30%), Positives = 52/101 (51%)
 Frame = +2

Query: 228 DTTLGGRKFDEVLVNHFCEEFGKKYKLDIKSKIRALLRLSQECEKLKKLMSANASDLPLS 287
           DT LGG  FD+ LV++  +   +K   D++   RA+ RL +  EK K+ +S+  S   + 
Sbjct: 2   DTHLGGEDFDQRLVDYLVKLIKQKTGRDVRHDTRAMSRLRRSAEKAKRALSSQHST-KVD 178

Query: 288 IECFMNDIDVSGTMNRGKFLEMCDDLLARVEPPLRSVLEQS 328
           ++   +D+    T+ R KF E+  DL       ++  LE S
Sbjct: 179 LDGVTSDL-ADLTLTRAKFEELNTDLFRSTLTTVKRALEDS 298
>13684
          Length = 438

 Score = 44.7 bits (104), Expect = 1e-04,   Method: Composition-based stats.
 Identities = 22/59 (37%), Positives = 33/59 (55%)
 Frame = -3

Query: 1   MSVVGIDLGFQSCYVAVARAGGIETIANEYSDRCTPACVSFGPKNRSIGAAAKSQVISN 59
           M+  G+ LG  S  +AV + G     AN+  DR TP  V+F   +  +GA+AK  ++SN
Sbjct: 178 MAAYGVHLGTCSACLAVYKDGKTSVAANDAGDRSTPCVVAFTACDAEVGASAKQGIVSN 2
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|115511018|ref|NP_033507.2| ubiquitin specific
protease 9, X chromosome [Mus musculus]
         (2554 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

35658                                                                 163   5e-40
31701                                                                 113   1e-36
30353                                                                 135   1e-31
11884                                                                  99   2e-20
26294                                                                  91   8e-20
08419                                                                  58   6e-08
30019                                                                  39   0.034
03515                                                                  37   0.15 
20945                                                                  36   0.24 
04261                                                                  35   0.29 
>35658
          Length = 406

 Score =  163 bits (412), Expect(2) = 5e-40,   Method: Compositional matrix adjust.
 Identities = 82/125 (65%), Positives = 95/125 (76%), Gaps = 1/125 (0%)
 Frame = -2

Query: 2132 PCPSPFASPGPSSQAYD-NLSLSDHLLRAVLNLLRREVSEHGRHLQQYFNLFVMYANLGV 2190
            P P P      +SQ  D N +LSDH+L AVL LLR+EVSEHGRHLQQYF+LF+MY NLG 
Sbjct: 375  PRPPPLLQGLYASQPADPNATLSDHVLSAVLTLLRKEVSEHGRHLQQYFHLFLMYCNLGP 196

Query: 2191 AEKTQLLKLSVPATFMLVSLDEGPGPPIKYQYAELGKLYSVVSQLIRCCNVSSRMQSSIN 2250
             EK QLLKL+VP   MLV+LDEGPGPPIKYQ+AEL KLYS VS L+RCC+VS R  SS+N
Sbjct: 195  EEKEQLLKLNVPQLLMLVALDEGPGPPIKYQHAELSKLYSTVSHLVRCCDVSHRCVSSVN 16

Query: 2251 GNPSL 2255
              P +
Sbjct: 15   NQPPM 1

 Score = 22.3 bits (46), Expect(2) = 5e-40,   Method: Composition-based stats.
 Identities = 8/12 (66%), Positives = 9/12 (75%)
 Frame = -1

Query: 2125 HFSLQDGPCPSP 2136
            H S +DGP PSP
Sbjct: 397  HASQKDGPSPSP 362
>31701
          Length = 497

 Score =  113 bits (283), Expect(2) = 1e-36,   Method: Compositional matrix adjust.
 Identities = 52/76 (68%), Positives = 59/76 (77%)
 Frame = -2

Query: 2287 KKIIEDCSNSDETVKLLRFCCWENPQFSSTVLSELLWQVAYSYTYEXXXXXXXXXXXXXI 2346
            +K+IE+C+NSD+T KLL+FC WENP FSSTVLSELLWQVAYSYTYE             +
Sbjct: 229  QKLIEECNNSDDTAKLLKFCSWENPHFSSTVLSELLWQVAYSYTYELRPYLDLLLQMLMV 50

Query: 2347 EDSWQTHRIHNALKGI 2362
            EDSWQ HRIHNALKGI
Sbjct: 49   EDSWQHHRIHNALKGI 2

 Score = 60.5 bits (145), Expect(2) = 1e-36,   Method: Composition-based stats.
 Identities = 35/72 (48%), Positives = 45/72 (62%), Gaps = 1/72 (1%)
 Frame = -3

Query: 2224 ELGKLYSVVSQLIRCCNVSSRMQSSI-NGNPSLPNPFGDPNLSQPIMPIQQNVVDILFVR 2282
            EL KLYS VS L+RCC+VS R  SS+ N  P   NP+ D    +P+MP+Q  V DIL  R
Sbjct: 420  ELSKLYSTVSHLVRCCDVSHRCVSSVNNQPPMPNNPYTDAQCPRPLMPLQPQVEDILLTR 241

Query: 2283 TSYVKKIIEDCS 2294
            T YVK ++   +
Sbjct: 240  TIYVKNLLRSAT 205
>30353
          Length = 404

 Score =  135 bits (341), Expect = 1e-31,   Method: Compositional matrix adjust.
 Identities = 77/142 (54%), Positives = 95/142 (66%), Gaps = 8/142 (5%)
 Frame = -1

Query: 727 LDPSLLTENGMKCF--------ERFFKAVNCREGKLVAKRRAYMMDDLELIGLDYLWRVV 778
           LD SLLTE   +          E    ++N   G L        MDD+ELIGLDY+WRVV
Sbjct: 404 LDASLLTEMASRVLSGSQAGQLEETSCSLNVAGGCL--------MDDMELIGLDYVWRVV 249

Query: 779 IQSNDDIACRAIDLLKEIYTNLGPRLQVNQVVIHEDFIQSCFDRLKASYDTLCVLDGDKD 838
           + + D++A +A++LLK+I+TNLGPRLQ NQV IHEDFI SC DRLKA YDT+ VL GD+D
Sbjct: 248 LLAPDEVADKAVNLLKDIFTNLGPRLQQNQVDIHEDFIGSCIDRLKALYDTVTVLRGDQD 69

Query: 839 SINCARQEAVRMVRVLTVLREY 860
           S +   QE VRM RVL VL+EY
Sbjct: 68  SSHRLVQETVRMGRVLNVLKEY 3
>11884
          Length = 952

 Score = 99.4 bits (246), Expect = 2e-20,   Method: Composition-based stats.
 Identities = 64/200 (32%), Positives = 96/200 (48%), Gaps = 1/200 (0%)
 Frame = +3

Query: 1709 MLSKVLGGSFADQKICQGCPHRYECEESFTTLNVDIRNHQNLLDSLEQYVKGDLLEGANA 1768
            ++ +V GG    Q  C  C  R    E F  L++++++   +  +L +YVK + L+ ANA
Sbjct: 9    VIHQVFGGFLRSQVQCLKCGARSNTFEPFMDLSLNLKDVNTVEAALGKYVKPETLDAANA 188

Query: 1769 YHCEKCNKKVDTVKRLLIKKLPPVLAIQLKRFDYDWERECAIKFNDYFEFPRELDMEPYT 1828
            Y C+KC KK    KR  + K+P VL IQL RF +      A K N + +FP +L++  Y 
Sbjct: 189  YDCQKCRKKTQARKRFSLHKIPNVLTIQLNRFGFT---RAAGKINKHIQFPEKLNVRQY- 356

Query: 1829 VAGVAKLEGDNVNPESQLIQQNEQSESEKAGSTKYRLVGVLVHSG-QASGGHYYSYIIQR 1887
               +++ +GD   PE                   Y L GVL+HSG   + GHYY Y+   
Sbjct: 357  ---MSRRQGD---PEY------------------YHLYGVLIHSGHHCNMGHYYCYV--- 455

Query: 1888 NGGDGEKNRWYKFDDGDVTE 1907
                   N WY  +D  V +
Sbjct: 456  ---RSPANSWYIMNDSSVHQ 506
>26294
          Length = 430

 Score = 90.5 bits (223), Expect(2) = 8e-20,   Method: Composition-based stats.
 Identities = 39/68 (57%), Positives = 51/68 (75%)
 Frame = +2

Query: 994  YSDGPNPEVESCLPGVIMSLHPRYISFLWQVADLGSSLNMPPLRDGARVLMKLMPPDSTT 1053
            + DGPN E ESCLPGVIM+ + RY SFL+Q++DLG  L +P LRDGAR +++LMP    T
Sbjct: 104  HCDGPNVEAESCLPGVIMAQNARYTSFLFQLSDLGCQLQIPRLRDGARAVLRLMPAGKHT 283

Query: 1054 IEKLRAIC 1061
            I+K  A+C
Sbjct: 284  IQKFCAVC 307

 Score = 27.3 bits (59), Expect(2) = 8e-20,   Method: Composition-based stats.
 Identities = 12/17 (70%), Positives = 13/17 (76%)
 Frame = +3

Query: 1086 SQVLYLTEVVYALLMPA 1102
            +QVLY  EV Y LLMPA
Sbjct: 375  TQVLYNIEVCYCLLMPA 425
>08419
          Length = 731

 Score = 57.8 bits (138), Expect = 6e-08,   Method: Compositional matrix adjust.
 Identities = 55/184 (29%), Positives = 81/184 (44%), Gaps = 4/184 (2%)
 Frame = +1

Query: 1779 DTVKRLLIKKLPPVLAIQLKRFDYDWERECAIKFNDYFEFPRELDMEPYTVAGVAKLEGD 1838
            D  +R L+ +LP  L IQL RF Y+ ++ C+ K              P ++    +L+G 
Sbjct: 106  DIQRRCLLSQLPECLIIQLMRFQYNAQQGCSTKLR-----------APVSI----RLKGL 240

Query: 1839 NV-NPESQLIQQNEQSESEKAGSTK-YRLVGVLVHSGQASG--GHYYSYIIQRNGGDGEK 1894
            N+ +     + Q E   S    S++ Y L G+ +H G  S   GHY SY +         
Sbjct: 241  NLQDLMCDTVTQREDCVSPGQNSSQMYDLYGLCLHIGADSTHHGHYISYSL------ASD 402

Query: 1895 NRWYKFDDGDVTECKMDDDEEMKNQCFGGEYMGEVFDHMMKRMSYRRQKRWWNAYILFYE 1954
            +RWY++DD  VTE  ++ +   K          EV           RQ    NAYILFY+
Sbjct: 403  SRWYRYDDEAVTEVNIEYELTTK----------EV-----------RQ----NAYILFYK 507

Query: 1955 RMDT 1958
            R  T
Sbjct: 508  RATT 519
>30019
          Length = 394

 Score = 38.5 bits (88), Expect = 0.034,   Method: Compositional matrix adjust.
 Identities = 33/114 (28%), Positives = 49/114 (42%), Gaps = 6/114 (5%)
 Frame = +1

Query: 1719 ADQKICQGCPH----RYECEESFT-TLNVDIRNHQNLLDSLEQYVKGDLLEGANAYHCEK 1773
            A + +C GC      RY+  +S T  L    R+  +L   L +Y+  + L       C+ 
Sbjct: 67   APEIVCNGCGSKSAVRYDKFDSVTLNLPEQRRSGLSLGHLLSEYITSEDLSDVK---CDS 237

Query: 1774 CNKKVDTVKRLLIKKLPPVLAIQLKRFDY-DWERECAIKFNDYFEFPRELDMEP 1826
            CN+     K +   KLP  L I + R  + +  + C  K  DY  FP  L M P
Sbjct: 238  CNEATMHTKSVTFAKLPACLCIHIARTIWLNTGQLC--KRQDYVHFPESLSMAP 393
>03515
          Length = 2030

 Score = 36.6 bits (83), Expect = 0.15,   Method: Composition-based stats.
 Identities = 27/111 (24%), Positives = 45/111 (40%)
 Frame = -1

Query: 1845 QLIQQNEQSESEKAGSTKYRLVGVLVHSGQASGGHYYSYIIQRNGGDGEKNRWYKFDDGD 1904
            Q+ ++ +  +SE     +Y L  +  H+G   GGHY +Y    NG      +WY ++D  
Sbjct: 2021 QIEEKLKLYDSEDFTGAQYDLYAMSCHTGIMGGGHYVAYSKNPNG------KWYCYND-- 1866

Query: 1905 VTECKMDDDEEMKNQCFGGEYMGEVFDHMMKRMSYRRQKRWWNAYILFYER 1955
             + CK   ++++                              +AYILFYER
Sbjct: 1865 -SSCKEVQEDQLDTN---------------------------SAYILFYER 1797
>20945
          Length = 386

 Score = 35.8 bits (81), Expect = 0.24,   Method: Composition-based stats.
 Identities = 17/51 (33%), Positives = 32/51 (62%)
 Frame = +3

Query: 388 EWIQQNNILSIVLRDSLHQPQYVEKLEKILRFVIKEKALTLQDLDNIWAAQ 438
           +W+ +++ILSI L  ++ Q QY +K++ I+ F+     L++ +L  IW  Q
Sbjct: 36  DWLVEHHILSIALEGNIDQAQYCDKIKGIVDFL--GSRLSVDELAMIWKIQ 182
>04261
          Length = 1792

 Score = 35.4 bits (80), Expect = 0.29,   Method: Compositional matrix adjust.
 Identities = 19/54 (35%), Positives = 30/54 (55%)
 Frame = +2

Query: 1749 NLLDSLEQYVKGDLLEGANAYHCEKCNKKVDTVKRLLIKKLPPVLAIQLKRFDY 1802
            +L D+++ Y K + +E    Y CE C++          KKLP +L + LKRF+Y
Sbjct: 371  SLKDAVKNYFKTEEIE----YSCEFCHQHTKAELSSRFKKLPRILILYLKRFEY 520
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|211065515|ref|NP_001032935.2| CCR4-NOT transcription
complex, subunit 2 isoform a [Mus musculus]
         (540 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

35074                                                                 160   5e-40
19724                                                                  30   1.7  
>35074
          Length = 654

 Score =  160 bits (404), Expect(2) = 5e-40,   Method: Compositional matrix adjust.
 Identities = 92/205 (44%), Positives = 119/205 (58%), Gaps = 13/205 (6%)
 Frame = +2

Query: 341 GRVTNIPQGMVTDQFGMIGLLTFIRAAETDPGMVHLALGSDLTTLGLNLNSPENLYPKFA 400
            R  NIP  MV +QFGM+GLLTFIRAAETDP +V L+LG+DLT LGLNLNS E+L+P FA
Sbjct: 59  ARSQNIPASMVNNQFGMVGLLTFIRAAETDPNLVTLSLGTDLTGLGLNLNSQESLHPTFA 238

Query: 401 SPWASSPCRPQDIDFHVPSEYLTNIHIRDKLAAIKLGRYGEDLLFYLYYMNGGDVLQLLA 460
            P+   PCR QD++++VP EYL N  IRDKL A  L +  EDLLF+        VL    
Sbjct: 239 GPFVEQPCRAQDVEYNVPPEYLINFAIRDKLTAPVLKKLQEDLLFF-------PVLHEYR 397

Query: 461 AVELFNRD-------WRYHKEERVWITRAPGMEPTMKTNTYERGTY--YFFDCLNWRKV- 510
                N          RYH EE++WITR PG+      N YE+             RKV 
Sbjct: 398 *YNAINGSG*IA*S*VRYHVEEKIWITRIPGI------NQYEKMVQKSVALSITLMRKVG 559

Query: 511 ---AKEFHLEYDKLEERPHLPSTFN 532
              +K F ++ +KL++ P++ +  N
Sbjct: 560 NVLSKVFQIDAEKLDKCPNISAFMN 634

 Score = 23.1 bits (48), Expect(2) = 5e-40,   Method: Compositional matrix adjust.
 Identities = 8/13 (61%), Positives = 10/13 (76%)
 Frame = +1

Query: 332 KKGIQVLPDGRVT 344
           K G+Q  PDG+VT
Sbjct: 31  KSGVQTSPDGKVT 69
>19724
          Length = 610

 Score = 30.4 bits (67), Expect = 1.7,   Method: Compositional matrix adjust.
 Identities = 54/189 (28%), Positives = 75/189 (39%), Gaps = 8/189 (4%)
 Frame = +2

Query: 56  KDMLASPSTS-GQLSQFG--ASLYGQQSALGLPMRGMSNNTPQLNRSLSQGTQLPSHVTP 112
           KD+   PS S  QLS FG   S Y   S+L LP R        +     + T  P+ + P
Sbjct: 161 KDIGIMPSQSPSQLSGFGQTGSFYTPASSLALPQR-------PIGSGQYRNTGTPTSINP 319

Query: 113 TTGVPTMSLHTPP---SPSRGILPMNPRNMM-NHSQVGQGIGIPXXXXXXXXXXXXXXXX 168
             G P+M L  PP   SP+  I  + PR+M+ + +Q GQ   +                 
Sbjct: 320 --GFPSMGLQQPPQQHSPNS-ISAIGPRSMLVSQNQSGQLNNL----------------- 439

Query: 169 XXXXIICMPKQQPSRQPFTVNSMSGFG-MNRNQAFGMNNSLSSNIFNGTDGSENVTGLDL 227
                         ++P   N+  G G M     FG   S  S+ F+          LDL
Sbjct: 440 -------------QKRPTVSNAFGGQGPMGNYSTFGGYGSSRSSTFDHPT-------LDL 559

Query: 228 SDFPALADR 236
           SDFP+L+ R
Sbjct: 560 SDFPSLSSR 586
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|21313162|ref|NP_083852.1| RAB1B, member RAS oncogene
family [Mus musculus]
         (201 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

34468                                                                 160   5e-40
08428                                                                 147   3e-36
33374                                                                 116   1e-33
05468                                                                 109   6e-25
26083                                                                 109   8e-25
14456                                                                 108   1e-24
32723                                                                 108   1e-24
07465                                                                 104   2e-23
33794                                                                 102   7e-23
17511                                                                 101   3e-22
33380                                                                  97   4e-22
13901                                                                  98   2e-21
01398                                                                  92   2e-19
30760                                                                  91   2e-19
01972                                                                  79   1e-18
07580                                                                  89   1e-18
11257                                                                  88   2e-18
01095                                                                  87   3e-18
19006                                                                  86   8e-18
35581                                                                  82   2e-16
00858                                                                  81   3e-16
34597                                                                  76   9e-16
26536                                                                  77   4e-15
12339                                                                  76   7e-15
27191                                                                  76   8e-15
13750                                                                  73   6e-14
11728                                                                  72   2e-13
13745                                                                  70   4e-13
34359                                                                  70   7e-13
19656                                                                  65   2e-11
09204                                                                  60   6e-10
29380                                                                  59   2e-09
19046                                                                  57   4e-09
24619                                                                  56   8e-09
25618                                                                  54   3e-08
09827                                                                  53   1e-07
08153                                                                  52   2e-07
33605                                                                  49   1e-06
00552                                                                  49   1e-06
14119                                                                  48   2e-06
14775                                                                  48   2e-06
10862                                                                  47   4e-06
18509                                                                  47   5e-06
31291                                                                  45   2e-05
25796                                                                  44   4e-05
12443                                                                  37   0.004
10708                                                                  33   0.090
18184                                                                  30   0.62 
31932                                                                  28   3.0  
28005                                                                  27   3.8  
06994                                                                  27   6.2  
>34468
          Length = 1502

 Score =  160 bits (404), Expect = 5e-40,   Method: Compositional matrix adjust.
 Identities = 78/195 (40%), Positives = 125/195 (64%), Gaps = 15/195 (7%)
 Frame = +1

Query: 8   LFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQ 67
           +FK+++IGDS VGK+CL  RF    + +   +TIGVDF+ ++I++D + +KLQ+WDTAGQ
Sbjct: 493 IFKIIVIGDSNVGKTCLTYRFCLGKFPDKTEATIGVDFREKSIQVDSEHLKLQLWDTAGQ 672

Query: 68  ERFR-TITSSYYRGAHGIIVVYDVTDQESYANVKQWLQEIDRY-ASENVNKLLVGNKSDL 125
           ERFR ++   YYR  H ++ VYD+T   S+ N+  W++E DR+  ++ + ++LVGNK D+
Sbjct: 673 ERFRKSMVQHYYRNVHAVVFVYDMTKMSSFENMPAWIEECDRHNLTKYIPRILVGNKCDV 852

Query: 126 TTKKVVDNTTAKEFADSLGVPFLETSAKN---ATNVEQAFMTMAAEIK----------KR 172
             +  V+   A++FAD+  +P  ETSAK+   A +V+  FMT+A ++K            
Sbjct: 853 VERIAVNTNLAQKFADAHNMPLFETSAKDDEKANHVDAIFMTVAHKLKXSKPMMPAHLSE 1032

Query: 173 MGPGAASGGERPNLK 187
           M PG  S G+  +L+
Sbjct: 1033MVPGDVSHGDLVHLR 1077
>08428
          Length = 1109

 Score =  147 bits (370), Expect = 3e-36,   Method: Compositional matrix adjust.
 Identities = 70/160 (43%), Positives = 100/160 (62%)
 Frame = -3

Query: 10   KLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQER 69
            K+ L+GDSGVGKS ++LRF   +Y  S  STIG  F  +++ +DG   + QIWDTAGQE+
Sbjct: 1065 KVCLLGDSGVGKSSIVLRFVTGSYRPSQESTIGASFMSKSLVVDGAGYRFQIWDTAGQEK 886

Query: 70   FRTITSSYYRGAHGIIVVYDVTDQESYANVKQWLQEIDRYASENVNKLLVGNKSDLTTKK 129
            FR +   YYRGA   ++VYDVT   ++ +VK W+QE+  +   N+   + GNK DL   +
Sbjct: 885  FRALAPMYYRGAAAAVIVYDVTRPRTFKSVKSWIQELRSFGPPNIVLAIAGNKCDLEELR 706

Query: 130  VVDNTTAKEFADSLGVPFLETSAKNATNVEQAFMTMAAEI 169
             V    A+E+A S+   F ETSA  A NVE+ F  +A ++
Sbjct: 705  EVVEKDAQEYASSISAIFGETSAMTAVNVEEMFTELARQL 586
>33374
          Length = 489

 Score =  116 bits (291), Expect(2) = 1e-33,   Method: Compositional matrix adjust.
 Identities = 53/114 (46%), Positives = 78/114 (68%)
 Frame = +1

Query: 45  FKIRTIELDGKTIKLQIWDTAGQERFRTITSSYYRGAHGIIVVYDVTDQESYANVKQWLQ 104
           F  +T+ LD  T+K +IWDTAGQER+ ++   YYRGA   IVVYD+T+Q+++   K W++
Sbjct: 139 FLTQTVCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNQDTFGRAKTWVK 318

Query: 105 EIDRYASENVNKLLVGNKSDLTTKKVVDNTTAKEFADSLGVPFLETSAKNATNV 158
           E+ R AS N+   L GNK+DL  K++V+   A+ +A+   + F+ETSAK A NV
Sbjct: 319 ELQRQASPNIVIALAGNKADLANKRMVEFEEAQAYAEENSLLFMETSAKTAMNV 480

 Score = 43.5 bits (101), Expect(2) = 1e-33,   Method: Compositional matrix adjust.
 Identities = 22/44 (50%), Positives = 28/44 (63%)
 Frame = +2

Query: 9  FKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIEL 52
          FKL+L+G+S VGKS L+LRF    + E   STIG  F +R   L
Sbjct: 32 FKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAF*LRQFVL 163
>05468
          Length = 1558

 Score =  109 bits (273), Expect = 6e-25,   Method: Compositional matrix adjust.
 Identities = 61/171 (35%), Positives = 100/171 (58%), Gaps = 7/171 (4%)
 Frame = -3

Query: 6    DYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKT-IKLQIWDT 64
            ++L+K+L+IG+ G GK+ ++ R+    +++ Y +TIGVDF ++ +  D  T I+LQ+WD 
Sbjct: 1547 EHLYKILVIGELGTGKTSIIKRYVHQFFSQHYRATIGVDFALKVLNWDADTLIRLQLWDI 1368

Query: 65   AGQERFRTITSSYYRGAHGIIVVYDVTDQESYANVKQWLQEIDRYAS----ENVNKLLVG 120
            AGQERF  +T  YY+ A G  VV+DVT   ++  V +W  ++D          V  +L+ 
Sbjct: 1367 AGQERFGNMTRVYYKEAVGAFVVFDVTRASTFDAVTKWKNDLDSKVQLADGSPVPCVLLA 1188

Query: 121  NKSDLTTKKVVDNTT-AKEFADSLG-VPFLETSAKNATNVEQAFMTMAAEI 169
            NK D   + +V+NT+   EF    G + + ETSAK   N+++A   +   I
Sbjct: 1187 NKCDQAKEGLVNNTSQMDEFCSEKGFIGWYETSAKENINIDEAARFLVTRI 1035
>26083
          Length = 432

 Score =  109 bits (272), Expect = 8e-25,   Method: Compositional matrix adjust.
 Identities = 49/114 (42%), Positives = 78/114 (68%)
 Frame = +1

Query: 9   FKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQE 68
           FKL+ +G+  VGK+ L+ RF  D++  +Y +TIG+DF  +T+ L+ +TI+LQ+WDTAGQE
Sbjct: 79  FKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTIRLQLWDTAGQE 258

Query: 69  RFRTITSSYYRGAHGIIVVYDVTDQESYANVKQWLQEIDRYASENVNKLLVGNK 122
           RFR++  SY R +   +VVYD+T+  S+    +W+ ++      +V  +LVGNK
Sbjct: 259 RFRSLIPSYIRDSSVAVVVYDITNANSFHQTSKWIDDVRTERGSDVIIMLVGNK 420
>14456
          Length = 1867

 Score =  108 bits (271), Expect = 1e-24,   Method: Compositional matrix adjust.
 Identities = 55/158 (34%), Positives = 91/158 (57%), Gaps = 4/158 (2%)
 Frame = -1

Query: 18   GVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRTITSSY 77
            GVGKS L+ RF  + +      TIGV+F  + + +D +T  +QIWDTAGQERF+++ + +
Sbjct: 1111 GVGKSSLMNRFVSNKFDAQSFHTIGVEFLNKDVVVDDETYTMQIWDTAGQERFKSLRTPF 932

Query: 78   YRGAHGIIVVYDVTDQESYANVKQWLQEIDRYAS----ENVNKLLVGNKSDLTTKKVVDN 133
            YRGA   ++ + V   +S+ N+  W +E   YA          +++GNK D+  ++V + 
Sbjct: 931  YRGADCCLLTFSVDSMQSFRNLSMWRKEFLYYADIQDGVTFPFVVLGNKIDVEGRQVTNE 752

Query: 134  TTAKEFADSLGVPFLETSAKNATNVEQAFMTMAAEIKK 171
                    +   P+ ETSAK+ATNVE+AF+     +++
Sbjct: 751  EARSWCTANSNAPYFETSAKDATNVEKAFLAAVQRLRE 638
>32723
          Length = 384

 Score =  108 bits (271), Expect = 1e-24,   Method: Compositional matrix adjust.
 Identities = 53/103 (51%), Positives = 70/103 (67%)
 Frame = +2

Query: 67  QERFRTITSSYYRGAHGIIVVYDVTDQESYANVKQWLQEIDRYASENVNKLLVGNKSDLT 126
           QERFR+IT SYYR A+ +I+VYDV  Q+SY ++ QW+ EI+ YA   V   LVGNK D T
Sbjct: 2   QERFRSITQSYYRSANALILVYDVCSQQSYESLPQWIHEIELYAGTKVLAFLVGNKIDQT 181

Query: 127 TKKVVDNTTAKEFADSLGVPFLETSAKNATNVEQAFMTMAAEI 169
            K+ +     KEFA+   + FLETSAK A NVE+ F T+A ++
Sbjct: 182 DKREIPTHIGKEFAERYEMRFLETSAKEADNVEKLFSTIAYQL 310
>07465
          Length = 1103

 Score =  104 bits (260), Expect = 2e-23,   Method: Compositional matrix adjust.
 Identities = 57/177 (32%), Positives = 94/177 (53%)
 Frame = +3

Query: 22  SCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRTITSSYYRGA 81
           S ++ R+    +T+ Y  TIGVDF  R IE+ G+ ++L +WDTAGQE F  IT +YYRGA
Sbjct: 240 SSMIQRYCKGIFTKDYKKTIGVDFLERQIEVGGEDVRLMLWDTAGQEEFDAITKAYYRGA 419

Query: 82  HGIIVVYDVTDQESYANVKQWLQEIDRYASENVNKLLVGNKSDLTTKKVVDNTTAKEFAD 141
              ++ +   D++S+  ++ W ++++    E +  ++V NK DL    VV    A+  A 
Sbjct: 420 QACVLAFSTVDRDSFEALETWKRKVEDEVGE-IGMVIVQNKIDLIDDAVVRPEEAENLAK 596

Query: 142 SLGVPFLETSAKNATNVEQAFMTMAAEIKKRMGPGAASGGERPNLKIDSTPVKPASG 198
            L + F  TS K   NV++ F  +A +   ++  G          +++ TP K   G
Sbjct: 597 KLRLRFYRTSVKENMNVDEVFRYLADKYLHQLNTGMD--------EVNLTPQKIGQG 743
>33794
          Length = 779

 Score =  102 bits (255), Expect = 7e-23,   Method: Compositional matrix adjust.
 Identities = 54/132 (40%), Positives = 80/132 (60%)
 Frame = -1

Query: 43  VDFKIRTIELDGKTIKLQIWDTAGQERFRTITSSYYRGAHGIIVVYDVTDQESYANVKQW 102
           V +K  TI L+GK +KLQIWDT+GQ RF TI  SY RGA GII+VYD+T++ S+  + +W
Sbjct: 692 VAYKTTTILLEGKRVKLQIWDTSGQGRFCTIIRSYSRGAQGIILVYDITNKWSFDGIDRW 513

Query: 103 LQEIDRYASENVNKLLVGNKSDLTTKKVVDNTTAKEFADSLGVPFLETSAKNATNVEQAF 162
           L+E++ +A   + K+LVGN+  L  K+ V    A+ +A    +   E S     N+ ++F
Sbjct: 512 LKEVEEHA-PGIPKVLVGNRLHLAYKRQVAAKQAETYASRNNMSCFEISPLCDFNIRESF 336

Query: 163 MTMAAEIKKRMG 174
             +A     R G
Sbjct: 335 CELARMALHRNG 300
>17511
          Length = 483

 Score =  101 bits (251), Expect = 3e-22,   Method: Compositional matrix adjust.
 Identities = 47/122 (38%), Positives = 80/122 (65%), Gaps = 4/122 (3%)
 Frame = -3

Query: 8   LFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQ 67
           L K++++GDSGVGK+ L+ ++ +  ++  Y +TIG DF  + + +D + + +QIWDTAGQ
Sbjct: 367 LLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQIWDTAGQ 188

Query: 68  ERFRTITSSYYRGAHGIIVVYDVTDQESYANVKQWLQEIDRYAS----ENVNKLLVGNKS 123
           ERF+++  ++YRGA   ++V+DVT   ++ ++  W  E    AS    EN   +++GNK 
Sbjct: 187 ERFQSLGVAFYRGADCCVLVFDVTMPNTFRSLDSWRDEFLIQASPRDPENFPFVVIGNKI 8

Query: 124 DL 125
           DL
Sbjct: 7   DL 2
>33380
          Length = 282

 Score = 96.7 bits (239), Expect(2) = 4e-22,   Method: Compositional matrix adjust.
 Identities = 44/82 (53%), Positives = 61/82 (74%)
 Frame = +3

Query: 49  TIELDGKTIKLQIWDTAGQERFRTITSSYYRGAHGIIVVYDVTDQESYANVKQWLQEIDR 108
           T+    K +KLQIWDTAGQER+RTIT++YYRGA G I++YDVT++ES+  V+ W  +I  
Sbjct: 36  TVFRQDKRVKLQIWDTAGQERYRTITTAYYRGAMGFILMYDVTNEESFNAVQDWCTQIKT 215

Query: 109 YASENVNKLLVGNKSDLTTKKV 130
           Y+ +N   +LVGNK DL  ++V
Sbjct: 216 YSWDNAQVVLVGNKCDLEDERV 281

 Score = 24.6 bits (52), Expect(2) = 4e-22,   Method: Compositional matrix adjust.
 Identities = 6/15 (40%), Positives = 14/15 (93%)
 Frame = +2

Query: 37 YISTIGVDFKIRTIE 51
          ++ST+G+DFK+ +++
Sbjct: 2  FVSTVGIDFKVNSLQ 46
>13901
          Length = 962

 Score = 98.2 bits (243), Expect = 2e-21,   Method: Compositional matrix adjust.
 Identities = 44/96 (45%), Positives = 65/96 (67%), Gaps = 1/96 (1%)
 Frame = -3

Query: 8   LFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGK-TIKLQIWDTAG 66
           LFK+++IGD  VGK+  + R+ +D++   Y  TIGVDF ++ I    K  IKLQ+WD AG
Sbjct: 288 LFKVIIIGDPTVGKTSFVQRYVNDSFRRDYKMTIGVDFALKVIRWSDKCNIKLQLWDIAG 109

Query: 67  QERFRTITSSYYRGAHGIIVVYDVTDQESYANVKQW 102
           QERF ++T  YY+ AH  IV++D+T + +Y N  +W
Sbjct: 108 QERFTSMTRVYYKDAHACIVMFDLTQKNTYQNAIRW 1
>01398
          Length = 1421

 Score = 92.0 bits (227), Expect = 2e-19,   Method: Compositional matrix adjust.
 Identities = 51/146 (34%), Positives = 76/146 (52%), Gaps = 11/146 (7%)
 Frame = -2

Query: 67   QERFRTITSSYYRGAHGIIVVYDVTDQESYANVKQWLQEIDRYASENVNKLLV-GNKSDL 125
            QERFR+IT SYYR + G+I+VYD+T + ++ N+KQW +E   +   +    LV G+KSD 
Sbjct: 1420 QERFRSITRSYYRNSVGVIIVYDITKRSTFENLKQWYEEARNHIEPHKAIFLVLGHKSDR 1241

Query: 126  TTKKVVDNTTAKEFADSLGVPFLETSAKNATNVEQAFMTMAAEIKKRMG----------P 175
               + V     + FA+  G+ F ETSAK+  N+E  F  +A +  + +            
Sbjct: 1240 EDARQVTAREGRRFAEMHGLKFFETSAKSGHNIEDVFAQIAKDTYQHLQDGHIRLEEGWD 1061

Query: 176  GAASGGERPNLKIDSTPVKPASGGCC 201
            G   G  RP   +     +  SGGCC
Sbjct: 1060 GVKQGFARPRETVHLAEGEE-SGGCC 986
>30760
          Length = 596

 Score = 91.3 bits (225), Expect = 2e-19,   Method: Compositional matrix adjust.
 Identities = 54/168 (32%), Positives = 94/168 (55%), Gaps = 6/168 (3%)
 Frame = -1

Query: 10  KLLLIGDSGVGKSCLLLRFADDT--YTESYISTIGVDFKIRTIEL-DGK-TIKLQIWDTA 65
           K ++ GDSGVGKS +   F  D+  + ++Y  T GV+  ++ + + D +  ++L ++D+A
Sbjct: 524 KCIVTGDSGVGKSSICQVFHSDSAHFPKNYSMTTGVEVLVKLVNIPDSRDQVELYLFDSA 345

Query: 66  GQERFRTITSSYYRGAHGIIVVYDVTDQESYANVKQWLQEIDRYASEN--VNKLLVGNKS 123
           G+E F    + ++     ++VVYDVTD+ S++   +WL+ + R A  N  +  +LV NK+
Sbjct: 344 GKEIFSENVTKFWDQPSVVMVVYDVTDETSFSGCVRWLERV-RAAKPNTVIPGVLVANKT 168

Query: 124 DLTTKKVVDNTTAKEFADSLGVPFLETSAKNATNVEQAFMTMAAEIKK 171
           DL  ++ V     K+ A S G+ + E SAK   N +  F  +A    K
Sbjct: 167 DLDERRRVSRKEGKDLAQSHGLEYFECSAKEMQNTDTPFFCLAHAFHK 24
>01972
          Length = 2359

 Score = 79.3 bits (194), Expect(2) = 1e-18,   Method: Compositional matrix adjust.
 Identities = 41/135 (30%), Positives = 72/135 (53%)
 Frame = +3

Query: 35  ESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRTITSSYYRGAHGIIVVYDVTDQE 94
           + Y++T+GV+            +K  +WDTAGQE+F  +   YY      ++++DVT + 
Sbjct: 381 KKYVATLGVEVHPLLFHTSRGKLKFNVWDTAGQEKFGGLRDGYYIQGQCAVIMFDVTSRV 560

Query: 95  SYANVKQWLQEIDRYASENVNKLLVGNKSDLTTKKVVDNTTAKEFADSLGVPFLETSAKN 154
           +Y NV  W +++ R   EN+  +L GNK D+  +KV     A  F     + + + SAK+
Sbjct: 561 TYKNVPNWHRDLVR-VCENIPIVLCGNKVDIKDRKV--KAKAIVFHRKKNLQYYDISAKS 731

Query: 155 ATNVEQAFMTMAAEI 169
             N E+ F+ +A ++
Sbjct: 732 NYNFEKPFLWLARKL 776

 Score = 30.0 bits (66), Expect(2) = 1e-18,   Method: Compositional matrix adjust.
 Identities = 12/35 (34%), Positives = 21/35 (60%)
 Frame = +1

Query: 4   EYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYI 38
           E +  FKL+L+GD GVGK+  + R     + ++ +
Sbjct: 289 EQEPTFKLVLVGDGGVGKTTFVKRHVTGEFEKNML 393
>07580
          Length = 921

 Score = 89.0 bits (219), Expect = 1e-18,   Method: Compositional matrix adjust.
 Identities = 48/141 (34%), Positives = 80/141 (56%), Gaps = 1/141 (0%)
 Frame = +3

Query: 33  YTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRTITSSYYRGAHGIIVVYDVTD 92
           + E Y  TI   ++ + +E+DG+   L+I DTAG E+F  +   Y +   G ++ Y +T 
Sbjct: 135 FVEKYDPTIEDSYR-KQVEVDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFLLAYSITA 311

Query: 93  QESYANVKQWLQEIDRYA-SENVNKLLVGNKSDLTTKKVVDNTTAKEFADSLGVPFLETS 151
           Q ++ ++++  ++I R   +++V  LLVGNK DL  ++VV     +  A S    FLETS
Sbjct: 312 QSTFNDLQELREQILRVKDTDDVPMLLVGNKCDLEDERVVGKDQGQGLARSFSCAFLETS 491

Query: 152 AKNATNVEQAFMTMAAEIKKR 172
           AK   NV + FM +  +I K+
Sbjct: 492 AKARINVNEIFMDLVRQINKK 554
>11257
          Length = 1102

 Score = 88.2 bits (217), Expect = 2e-18,   Method: Compositional matrix adjust.
 Identities = 47/160 (29%), Positives = 83/160 (51%), Gaps = 6/160 (3%)
 Frame = -2

Query: 48   RTIELDGKTIKLQIWDTAGQERFRTITSSYYRGAHGIIVVYDVTDQESYANVKQWLQEID 107
            + + +DG+T  +QIWDTAGQER++++ + +YRG    ++ + V + +S  ++  W  E  
Sbjct: 1053 KDVVVDGETFTMQIWDTAGQERYKSLRTPFYRGTDCCLLTFSVDNLKSLQSLSDWYDEFV 874

Query: 108  RYA----SENVNKLLVGNKSDLTTKKVVDNTTAKEFADSLGVPFLETSAKNATNVEQAFM 163
             YA    S +   +++GNK+D+  ++V              +P+ ETSAK++ NV+QAF+
Sbjct: 873  NYADIQDSASFPFVIIGNKADIEEREVSSEDAYNWCRTHGNLPYFETSAKDSLNVQQAFL 694

Query: 164  TMAAEIKKRMGPGAASGGERPNL--KIDSTPVKPASGGCC 201
             +     +R+        ERP     +D   V      CC
Sbjct: 693  AVV----RRLREMDEQMDERPTRTDTVDLKRVAKVKSSCC 586
>01095
          Length = 1745

 Score = 87.4 bits (215), Expect = 3e-18,   Method: Compositional matrix adjust.
 Identities = 42/116 (36%), Positives = 72/116 (62%)
 Frame = -1

Query: 86   VVYDVTDQESYANVKQWLQEIDRYASENVNKLLVGNKSDLTTKKVVDNTTAKEFADSLGV 145
            VVYD+T+Q+++   K W++E+ R AS N+   L GNK+DL  K++V+   A+ +A+   +
Sbjct: 1745 VVYDITNQDTFGRAKTWVKELQRQASPNIVIALAGNKADLANKRMVEFEEAQAYAEENSL 1566

Query: 146  PFLETSAKNATNVEQAFMTMAAEIKKRMGPGAASGGERPNLKIDSTPVKPASGGCC 201
             F+ETSAK A NV   F+ +A ++ K  G G  S   +  +++++   + + GGCC
Sbjct: 1565 LFMETSAKTAMNVNDIFLAIAKKLPKNEG-GGGSQPRQQGVRLNNEQSQQSEGGCC 1401
>19006
          Length = 568

 Score = 86.3 bits (212), Expect = 8e-18,   Method: Compositional matrix adjust.
 Identities = 45/131 (34%), Positives = 75/131 (57%), Gaps = 1/131 (0%)
 Frame = -2

Query: 10  KLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQER 69
           KL+++GD   GK+CLL+ F+ D + E Y+ T+  ++ +  IE+D K ++L +WDTAGQE 
Sbjct: 432 KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENY-VADIEVDSKQVELALWDTAGQED 256

Query: 70  FRTITSSYYRGAHGIIVVYDVTDQESYANV-KQWLQEIDRYASENVNKLLVGNKSDLTTK 128
           +  +    Y     I++ + +   +S  N+ ++W  E+ R+   NV  +LVGNK DL   
Sbjct: 255 YDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEV-RHFCPNVPIILVGNKKDLRN- 82

Query: 129 KVVDNTTAKEF 139
              D  T +E 
Sbjct: 81  ---DENTKREL 58
>35581
          Length = 364

 Score = 81.6 bits (200), Expect = 2e-16,   Method: Compositional matrix adjust.
 Identities = 37/82 (45%), Positives = 57/82 (69%), Gaps = 1/82 (1%)
 Frame = +2

Query: 9   FKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIEL-DGKTIKLQIWDTAGQ 67
           FK +L+GD+GVGK+CLL R A D + +S ++++     + T+ L  G    + +WDTAGQ
Sbjct: 47  FKCVLLGDAGVGKTCLLNRLATDKFLDSPLTSLTTASLLTTVTLTSGVMASVDLWDTAGQ 226

Query: 68  ERFRTITSSYYRGAHGIIVVYD 89
           ER+R++TSSYYR    +++VYD
Sbjct: 227 ERYRSLTSSYYRDTKAVLIVYD 292
>00858
          Length = 1658

 Score = 80.9 bits (198), Expect = 3e-16,   Method: Compositional matrix adjust.
 Identities = 55/162 (33%), Positives = 89/162 (54%), Gaps = 1/162 (0%)
 Frame = -2

Query: 9    FKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQE 68
            +KL+++G  GVGKS L ++   + + E Y  T   D   + + +DG+T  L I DTAGQE
Sbjct: 1588 YKLVVVGAGGVGKSALTIQLXQNHFVEEYDPTXE-DSXRKQVVIDGETCLLDILDTAGQE 1412

Query: 69   RFRTITSSYYRGAHGIIVVYDVTDQESYANVKQWLQEIDRYA-SENVNKLLVGNKSDLTT 127
                +     R   G + V+ V + +S+ ++ Q+ ++I R   ++ V  +LVGNK DL  
Sbjct: 1411 EXSAMRDQCMRTGEGFLCVFAVXNLKSFEDINQYREQIKRVKDADEVPMVLVGNKVDLPI 1232

Query: 128  KKVVDNTTAKEFADSLGVPFLETSAKNATNVEQAFMTMAAEI 169
            +  V+    K  A+   +P++ETSAK    V+ AF T+  EI
Sbjct: 1231 RN-VEQRQGKHMAELYHIPYVETSAKTRQGVDDAFYTLVREI 1109
>34597
          Length = 773

 Score = 76.3 bits (186), Expect(2) = 9e-16,   Method: Compositional matrix adjust.
 Identities = 39/110 (35%), Positives = 64/110 (58%), Gaps = 1/110 (0%)
 Frame = -2

Query: 93  QESYANVKQWLQEIDRYASENVNKLLVGNKSDLTTKKVVDNTTAKEFADSLGVPFLETSA 152
           ++S+ N+ +WL+ ID +A+E+V K+++GNK D+T K+VV     +  A    + F+ETSA
Sbjct: 715 KKSFENIVKWLRNIDEHANEDVEKMILGNKCDMTDKRVVSKERGEAIAREHSIRFMETSA 536

Query: 153 KNATNVEQAFMTMAAEI-KKRMGPGAASGGERPNLKIDSTPVKPASGGCC 201
           K+  N+E+AF  +A  I  K  G  +A   ER  +   ++   P    CC
Sbjct: 535 KSNINIERAFCELAEAILDKTAGRESAENPERVVIDRGNSDKAPGYNKCC 386

 Score = 23.5 bits (49), Expect(2) = 9e-16,   Method: Compositional matrix adjust.
 Identities = 9/13 (69%), Positives = 12/13 (92%)
 Frame = -3

Query: 75  SSYYRGAHGIIVV 87
           +SYYRGA GI++V
Sbjct: 771 TSYYRGAMGIMLV 733
>26536
          Length = 829

 Score = 77.0 bits (188), Expect = 4e-15,   Method: Compositional matrix adjust.
 Identities = 40/118 (33%), Positives = 64/118 (54%), Gaps = 1/118 (0%)
 Frame = +2

Query: 55  KTIKLQIWDTAGQERFRTITSSYYRGAHGIIVVYDVTDQESYANVKQWLQEIDRYASE-N 113
           + +     DTAGQE + ++   Y R   G IVVY VTD  S+   +   + + R+  E +
Sbjct: 122 RRVSWTFLDTAGQEEYSSMREHYTRSGDGFIVVYSVTDVTSFQEAEAVFRWLTRFQDETS 301

Query: 114 VNKLLVGNKSDLTTKKVVDNTTAKEFADSLGVPFLETSAKNATNVEQAFMTMAAEIKK 171
           ++ +L GNK+DLT+ + V     ++ AD LG+ + ETSAK   NV Q +  +   I +
Sbjct: 302 IHAVLCGNKTDLTSDRKVTPEEGRKMADRLGMLYFETSAKTGDNVSQVYHGLLRSIPR 475

 Score = 37.7 bits (86), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 17/47 (36%), Positives = 31/47 (65%)
 Frame = +2

Query: 9   FKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGK 55
           +K++++G  GVGKS L +RF  DT+ + Y  TI   ++ + I++ G+
Sbjct: 488 YKIVMLGSGGVGKSSLTIRFTQDTFLDVYDPTIEDSYR-KMIQVSGQ 625
>12339
          Length = 578

 Score = 76.3 bits (186), Expect = 7e-15,   Method: Compositional matrix adjust.
 Identities = 41/104 (39%), Positives = 63/104 (60%), Gaps = 4/104 (3%)
 Frame = -2

Query: 67  QERFRTITSSYYRGAHGIIVVYDVTDQESYANVKQWLQEIDRYAS----ENVNKLLVGNK 122
           QERF+++  ++YRGA   I+VYDVT+ +++ ++  W +E    AS    E+   +++GNK
Sbjct: 577 QERFQSLGVAFYRGADCCILVYDVTEXKTFDSLDSWQREFLNQASPRDPEHFPFVVIGNK 398

Query: 123 SDLTTKKVVDNTTAKEFADSLGVPFLETSAKNATNVEQAFMTMA 166
            DL  + V         +   G+P+ ETSAK A NVEQAF T+A
Sbjct: 397 IDLDNRVVTAKRGQGWCSTKGGIPYFETSAKEAINVEQAFQTVA 266
>27191
          Length = 443

 Score = 76.3 bits (186), Expect = 8e-15,   Method: Compositional matrix adjust.
 Identities = 29/102 (28%), Positives = 62/102 (60%)
 Frame = +1

Query: 21  KSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRTITSSYYRG 80
           K+CL+  F +  + + Y  T+GVD+  +   ++G  +++ +WD +G   +  + +  Y G
Sbjct: 1   KTCLIKHFCESKFNQGYQPTVGVDYGFKIQTVNGVDMRVHMWDLSGSNEYLDVRNELYTG 180

Query: 81  AHGIIVVYDVTDQESYANVKQWLQEIDRYASENVNKLLVGNK 122
           +  I +V+DV++  S+  +  WL+EI+R+A+ +   ++VGN+
Sbjct: 181 SDAIFIVFDVSNTPSFEALDSWLREINRFATGSPLNVIVGNR 306
>13750
          Length = 503

 Score = 73.2 bits (178), Expect = 6e-14,   Method: Compositional matrix adjust.
 Identities = 47/151 (31%), Positives = 78/151 (51%), Gaps = 5/151 (3%)
 Frame = -2

Query: 21  KSCLLLRFADDTYTESYISTIGV---DF-KIRTIELDGKTIKLQIWDTAGQERFRTITSS 76
           K+CLL R+    + +  + TI V   +F + RT   D   ++  +WDT G E +R++  S
Sbjct: 502 KTCLLRRYQKGFFMDRTMPTIAVLCSEFNESRT---DPLNVRYTLWDTGGAETYRSLWVS 332

Query: 77  YYRGAHGIIVVYDVTDQESYANVKQ-WLQEIDRYASENVNKLLVGNKSDLTTKKVVDNTT 135
           ++RGA   ++VYDVT + S+      W + + +   E    + VG+K+DL   +V+    
Sbjct: 331 HFRGAQVALLVYDVTCEWSFLTATTVWRKALMKNIPE-AQVIFVGSKTDLEENRVISTER 155

Query: 136 AKEFADSLGVPFLETSAKNATNVEQAFMTMA 166
            + FA   G  F ETS+    NV+  F  +A
Sbjct: 154 GQAFATQCGYTFFETSSVTGKNVDAVFWEIA 62
>11728
          Length = 635

 Score = 71.6 bits (174), Expect = 2e-13,   Method: Compositional matrix adjust.
 Identities = 40/134 (29%), Positives = 69/134 (51%), Gaps = 2/134 (1%)
 Frame = -1

Query: 9   FKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQE 68
            K +++GD  VGK+CLL+ +  + +   YI T+  ++    + +D K I L +WDTAGQE
Sbjct: 488 IKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVM-VDSKPINLGLWDTAGQE 312

Query: 69  RFRTITSSYYRGAHGIIVVYDVTDQESYANVK-QWLQEIDRYASENVNKLLVGNKSDLTT 127
            +  +    Y      ++ + +    S+ NVK +W  E+  +   N   +LVG K DL  
Sbjct: 311 DYDRLRPLSYPQTDVFLICFSLISPASFENVKAKWYPEVSHHCP-NTPIILVGTKLDLRE 135

Query: 128 -KKVVDNTTAKEFA 140
            K+ ++    K+ A
Sbjct: 134 DKETIEKLKEKKLA 93
>13745
          Length = 1045

 Score = 70.5 bits (171), Expect = 4e-13,   Method: Compositional matrix adjust.
 Identities = 42/139 (30%), Positives = 69/139 (49%), Gaps = 4/139 (2%)
 Frame = +2

Query: 67  QERFRTITSSYYRGAHGIIVVYDVTDQESYANVKQWLQEIDRYAS----ENVNKLLVGNK 122
           QERF+++  ++YRGA   ++VYDVT   S+ N+  W  E    AS    E+   +++GNK
Sbjct: 2   QERFQSLGVAFYRGADCCVLVYDVTAPNSFKNLDSWRDEFLIQASPRDPEHFPFVVLGNK 181

Query: 123 SDLTTKKVVDNTTAKEFADSLGVPFLETSAKNATNVEQAFMTMAAEIKKRMGPGAASGGE 182
            DL  ++V      +       +P+ ETSAK   NVE AF T+A    ++          
Sbjct: 182 VDLDNRQVSTRRAQQWCQSKNDIPYYETSAKEGINVEMAFQTIAKNALEQETEAELINDF 361

Query: 183 RPNLKIDSTPVKPASGGCC 201
              ++++S   +P +   C
Sbjct: 362 PDQIRLNSENNRPGNADNC 418
>34359
          Length = 1042

 Score = 69.7 bits (169), Expect = 7e-13,   Method: Compositional matrix adjust.
 Identities = 38/122 (31%), Positives = 66/122 (54%)
 Frame = +3

Query: 9   FKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQE 68
           FKL+L+G      + ++ R    +  + Y++T+GV+            ++  +WDTAGQE
Sbjct: 54  FKLVLVGGRWEWANNIVKRHVTGS*-KKYVATLGVEVHPLQFNTSRGLLRFNVWDTAGQE 230

Query: 69  RFRTITSSYYRGAHGIIVVYDVTDQESYANVKQWLQEIDRYASENVNKLLVGNKSDLTTK 128
           +F  +   YY      I+++DVT + +Y NV  W +++ R   EN+  +L GNK D+  +
Sbjct: 231 KFGGLRDGYYIQGTCAIIMFDVTSRVTYKNVPNWHRDLVR-VCENIPIVLCGNKVDIKDR 407

Query: 129 KV 130
           KV
Sbjct: 408 KV 413
>19656
          Length = 428

 Score = 65.5 bits (158), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 29/102 (28%), Positives = 55/102 (53%), Gaps = 1/102 (0%)
 Frame = +3

Query: 10  KLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQER 69
           K +++GD  VGK+CLL+ +  + +   YI T+  D     + +DG+ + L +WDTAGQE 
Sbjct: 117 KCVVVGDGAVGKTCLLISYTTNAFPGEYIPTV-FDNYSANVMVDGRPVNLGLWDTAGQED 293

Query: 70  FRTITSSYYRGAHGIIVVYDVTDQESYANVK-QWLQEIDRYA 110
           +  +    Y      ++ + V    S+ N++ +W  E++ + 
Sbjct: 294 YDRLRPLSYPQTDVFLLCFSVASPASFENIRAKWYPEVNHHC 419
>09204
          Length = 1051

 Score = 60.1 bits (144), Expect = 6e-10,   Method: Compositional matrix adjust.
 Identities = 32/107 (29%), Positives = 53/107 (49%), Gaps = 4/107 (3%)
 Frame = -3

Query: 69   RFRTITSSYYRGAHGIIVVYDVTDQESYANVKQWLQEIDRYASENVNKLLVGNKSDLT-- 126
            R+  ++  YYRGA   I+ +D+TD+ S+  ++ W+ E+ R   E     + G K DL   
Sbjct: 1049 RYEAMSRIYYRGAKAAILCFDLTDKSSFDRIRFWIGEL-RQHEEECKLYICGTKFDLVHD 873

Query: 127  --TKKVVDNTTAKEFADSLGVPFLETSAKNATNVEQAFMTMAAEIKK 171
               ++ V  + AK  AD       ETS+    N+E+ F  +A +  K
Sbjct: 872  DPERRAVPRSVAKALADDCMAEIYETSSMTGDNIEKLFTKIAEDYMK 732
>29380
          Length = 853

 Score = 58.5 bits (140), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 34/102 (33%), Positives = 58/102 (56%), Gaps = 1/102 (0%)
 Frame = -2

Query: 81  AHGIIVVYDVTDQESYANVKQWLQEIDRYASENVNKLLVGNKSDLTTK-KVVDNTTAKEF 139
           A   I+VYDV   ++++    W++E+ +  +E+V  +L GNK DL T+ + V    A+ F
Sbjct: 852 ASAAIIVYDVNIADTFSRALAWVKELRQQNTESVLIILAGNKVDLATQHRAVSFEDAQSF 673

Query: 140 ADSLGVPFLETSAKNATNVEQAFMTMAAEIKKRMGPGAASGG 181
           A   G+ F E SAK    V + FMT+A ++ ++   G+ + G
Sbjct: 672 ARENGLLFAEVSAKTGMAVNEIFMTLANQLIQQEIDGSRNRG 547
>19046
          Length = 445

 Score = 57.4 bits (137), Expect = 4e-09,   Method: Compositional matrix adjust.
 Identities = 33/106 (31%), Positives = 55/106 (51%), Gaps = 2/106 (1%)
 Frame = -2

Query: 67  QERFRTITSSYYRGAHGIIVVYDVTDQESYANVKQWLQEIDRYA-SENVNKLLVGNKSDL 125
           QE F  +   Y R   G ++V+ VTD  S+ N+  +  +I R    ++   +L  NK DL
Sbjct: 444 QEEFSAMREQYMRKGDGFLLVFSVTDFRSFENMANFHTQILRVKDRDSYPMILCANKVDL 265

Query: 126 TTKKVVDNTTAKEFADSLGVPFLETSAKNAT-NVEQAFMTMAAEIK 170
             ++ V     ++ A  L +P++ETSAK+   NV+ AF  +   I+
Sbjct: 264 VHQRKVSEEQVRDLATRLRIPYIETSAKDPPLNVDLAFHQVVRVIR 127
>24619
          Length = 509

 Score = 56.2 bits (134), Expect = 8e-09,   Method: Compositional matrix adjust.
 Identities = 32/106 (30%), Positives = 54/106 (50%), Gaps = 2/106 (1%)
 Frame = -2

Query: 67  QERFRTITSSYYRGAHGIIVVYDVTDQESYANVKQWLQEIDRYASENVNKL-LVGNKSDL 125
           QE F  +   Y R   G ++V+ V D +S+ N+  +  +I R    +   + L  NK DL
Sbjct: 508 QEEFSAMREQYMRKGDGFLLVFSVIDYQSFENMVNFHTQILRVKDRDTYPMILCANKVDL 329

Query: 126 TTKKVVDNTTAKEFADSLGVPFLETSAKNAT-NVEQAFMTMAAEIK 170
             ++ V     ++ A  L +P++ETSAK+   NV+ AF  +   I+
Sbjct: 328 VHQRKVSEEQVRDLATRLRIPYIETSAKDPPLNVDLAFHQVVRVIR 191
>25618
          Length = 475

 Score = 54.3 bits (129), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 33/87 (37%), Positives = 49/87 (56%), Gaps = 3/87 (3%)
 Frame = +3

Query: 117 LLVGNKSDLTTK-KVVDNTTAKEFADSLGVPFLETSAKNATNVEQAFMTMAAEIKKRM-- 173
           +L GNK+DL ++ + V    A+ FA+  G+ F E SAK    V + FMT+A ++ +R   
Sbjct: 87  VLAGNKADLASEHRAVSADDARTFAEDNGLIFAEVSAKTGMAVSEVFMTIAHKLVRRAEE 266

Query: 174 GPGAASGGERPNLKIDSTPVKPASGGC 200
           G G+  G ER  L    +  + ASGGC
Sbjct: 267 GQGSXQGRERVRL----SEAEEASGGC 335
>09827
          Length = 1201

 Score = 52.8 bits (125), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 37/123 (30%), Positives = 63/123 (51%), Gaps = 6/123 (4%)
 Frame = -3

Query: 9    FKLLLIGDSGVGKSCLL--LRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAG 66
             ++L++G    GK+ +L  L+  +   T   I TIG  F + T+E   K I   +WD  G
Sbjct: 1112 MRILMVGLDAAGKTTILYKLKLGEIVTT---IPTIG--FNVETVEY--KNISFTVWDVGG 954

Query: 67   QERFRTITSSYYRGAHGIIVVYDVTDQESYANVKQWLQEIDRYASENVNK----LLVGNK 122
            Q++ R +   Y++   G+I V D  D+E    V++  +E+ R  +E+  +    L+  NK
Sbjct: 953  QDKIRPLWRHYFQNTQGLIFVVDSNDKE---RVQEAREELTRMLNEDELRDAVLLVFANK 783

Query: 123  SDL 125
             DL
Sbjct: 782  QDL 774
>08153
          Length = 1703

 Score = 52.0 bits (123), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 37/122 (30%), Positives = 61/122 (50%), Gaps = 6/122 (4%)
 Frame = +1

Query: 10  KLLLIGDSGVGKSCLL--LRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQ 67
           ++L++G    GK+ +L  L+  +   T   I TIG  F + T+E   K I   +WD  GQ
Sbjct: 88  RILMVGLDAAGKTTILYKLKLGEIVTT---IPTIG--FNVETVEY--KNISFTVWDVGGQ 246

Query: 68  ERFRTITSSYYRGAHGIIVVYDVTDQESYANVKQWLQEIDRYASENVNK----LLVGNKS 123
           ++ R +   Y++   G+I V D  D+E     K   +E+ R  +E+  +    L+  NK 
Sbjct: 247 DKIRPLWRHYFQNTQGLIFVVDSNDRERINEAK---EELARMLNEDDLRDAIILVFANKQ 417

Query: 124 DL 125
           DL
Sbjct: 418 DL 423
>33605
          Length = 888

 Score = 48.9 bits (115), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 31/93 (33%), Positives = 51/93 (54%), Gaps = 1/93 (1%)
 Frame = +1

Query: 10  KLLLIGDSGVGKSCLLLRF-ADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQE 68
           +LL++G    GK+ +L +F  +D  T S   T+G  F I+T+E  G   KL +WD  GQ+
Sbjct: 502 RLLMLGLDNAGKTTILKKFNGEDIDTIS--PTLG--FNIKTLEHRG--FKLNVWDVGGQQ 663

Query: 69  RFRTITSSYYRGAHGIIVVYDVTDQESYANVKQ 101
             R+   +Y+    G++ V D  D+   A+ K+
Sbjct: 664 SLRSYWRNYFESTDGLVWVVDSADRMRIADCKR 762
>00552
          Length = 455

 Score = 48.9 bits (115), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 22/53 (41%), Positives = 34/53 (64%)
 Frame = -1

Query: 8   LFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQ 60
           L K++L+GD GVGKS L+ RF  + +      TIGV+F  + + +DG+T  +Q
Sbjct: 446 LLKVVLLGDGGVGKSSLMNRFVSNKFDAQSFHTIGVEFLTKDVVVDGETFTMQ 288

 Score = 44.7 bits (104), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 17/49 (34%), Positives = 30/49 (61%)
 Frame = -3

Query: 61  IWDTAGQERFRTITSSYYRGAHGIIVVYDVTDQESYANVKQWLQEIDRY 109
           IWDTAGQER++++ + +YRG    ++ + V + +S  ++  W  E   Y
Sbjct: 147 IWDTAGQERYKSLRTPFYRGTDCCLLTFSVDNLKSLQSLSDWYDEFVNY 1
>14119
          Length = 602

 Score = 48.1 bits (113), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 29/82 (35%), Positives = 48/82 (58%), Gaps = 3/82 (3%)
 Frame = +1

Query: 102 WLQEIDRYASENVNKLLVGNKSDLTTK-KVVDNTTAKEFADSLGVPFLETSAKNATNVEQ 160
           W++E+ +  + +V  +L GNK+DL ++ + V    A+ FA+  G+ F E SAK    V +
Sbjct: 22  WVKELRQQNAGSVLIVLAGNKADLASEHRAVSADDARTFAEDNGLIFAEVSAKTGMAVSE 201

Query: 161 AFMTMAAEIKKRM--GPGAASG 180
            FMT+A ++ +R   G G  SG
Sbjct: 202 VFMTIAHKLVRRAEEGGGVWSG 267
>14775
          Length = 380

 Score = 48.1 bits (113), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 26/82 (31%), Positives = 43/82 (52%), Gaps = 1/82 (1%)
 Frame = -2

Query: 21  KSCLLLRFADDTYTESYISTIGVDF-KIRTIELDGKTIKLQIWDTAGQERFRTITSSYYR 79
           K+CLL R+    + +  + TI V   +      D   ++  +WDT G E +R++  S++R
Sbjct: 379 KTCLLRRYQKGFFMDRTMPTIAVLCSEFNESRTDPLNVRYTLWDTGGAETYRSLWVSHFR 200

Query: 80  GAHGIIVVYDVTDQESYANVKQ 101
           GA   ++VYDVT +   A   Q
Sbjct: 199 GAQVALLVYDVTCERGQAFATQ 134
>10862
          Length = 2896

 Score = 47.4 bits (111), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 33/135 (24%), Positives = 54/135 (40%), Gaps = 2/135 (1%)
 Frame = -3

Query: 16   DSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRTITS 75
            D  VG  C    ++        +     + +I+      +  +  +WD  GQ++ R +  
Sbjct: 2609 DPHVGA*CCRENYSSIQNETRTVCDXNTNSRIQCRNCQLQECQFNVWDVGGQDKIRPLWR 2430

Query: 76   SYYRGAHGIIVVYDVTDQESYANVKQWLQEI--DRYASENVNKLLVGNKSDLTTKKVVDN 133
             YY G  G+I V D  D++     +Q L  I  DR   + +  L+  NK DL      D 
Sbjct: 2429 HYYTGTQGLIFVVDCADRDRIDEARQELHRIINDREMRDAI-ILIFANKQDLP-----DA 2268

Query: 134  TTAKEFADSLGVPFL 148
                E  + LG+  L
Sbjct: 2267 MKPHEIQEKLGLTRL 2223
>18509
          Length = 625

 Score = 47.0 bits (110), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 24/61 (39%), Positives = 36/61 (59%)
 Frame = -3

Query: 111 SENVNKLLVGNKSDLTTKKVVDNTTAKEFADSLGVPFLETSAKNATNVEQAFMTMAAEIK 170
           ++ V  +LVGNK DL  + V +    K  A+   +P++ETSAK    V+ AF T+  EI+
Sbjct: 536 ADEVPMVLVGNKVDLPIRNV-EQRQGKHMAELYHIPYVETSAKTRQGVDDAFYTLVREIR 360

Query: 171 K 171
           K
Sbjct: 359 K 357
>31291
          Length = 446

 Score = 45.4 bits (106), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 38/138 (27%), Positives = 60/138 (43%), Gaps = 21/138 (15%)
 Frame = -1

Query: 59  LQIWDTAGQERFRTITSSYYRGAHGIIVVYDVTDQESYANVK-QWLQEIDRYASENVNKL 117
           LQ+WDTAGQE +  +    Y      ++ + +  + S  NVK +W  EI R+   +V  +
Sbjct: 446 LQLWDTAGQEDYDRLRPLAYPNTDVFMLXFSLMSEASMKNVKVKWYPEI-RHHDPHVPIV 270

Query: 118 LVGNKSDLTTKK------------VVDNTTAKEFADSLGVP-FLETSAKNATNVEQAF-- 162
           LVG K DL   K             V +    + A ++    + E S+K   N++ AF  
Sbjct: 269 LVGTKLDLRQDKEAVRKLRSSRQDPVSSNQGNDLAKAIKAKRYFECSSKTQENLKTAFEE 90

Query: 163 -----MTMAAEIKKRMGP 175
                + M  +  KR  P
Sbjct: 89  TVRVALNMDGQNNKRPKP 36
>25796
          Length = 422

 Score = 43.9 bits (102), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 18/28 (64%), Positives = 21/28 (75%)
 Frame = -1

Query: 1  MNPEYDYLFKLLLIGDSGVGKSCLLLRF 28
          M+  YDYLFK L+IG +G GKSCLL  F
Sbjct: 89 MSETYDYLFKFLIIGSAGSGKSCLLHHF 6
>12443
          Length = 837

 Score = 37.4 bits (85), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 30/133 (22%), Positives = 66/133 (49%), Gaps = 9/133 (6%)
 Frame = -3

Query: 9   FKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVD----FKIRTIELDGKTI--KLQIW 62
           +K++L+G +GVGK+  + +   +    ++  T G+     +    I+  GKT+  ++Q++
Sbjct: 580 YKVMLVGKTGVGKTSTVAKLTGNDIPLTHNETPGLQTSHLYWPGKIKHLGKTVLFQIQLF 401

Query: 63  DTAGQ---ERFRTITSSYYRGAHGIIVVYDVTDQESYANVKQWLQEIDRYASENVNKLLV 119
           D AG+   +R+  I  +   G  GI+ ++   D+ S+  + Q L        + + K+ +
Sbjct: 400 D-AGETALKRYDHILPACQDGVDGIMFLFSFVDKGSFDEIPQLLTRFTT-LEDGICKIAL 227

Query: 120 GNKSDLTTKKVVD 132
           G K     K +++
Sbjct: 226 GTKYPFPHKGIIN 188
>10708
          Length = 2775

 Score = 32.7 bits (73), Expect = 0.090,   Method: Compositional matrix adjust.
 Identities = 12/47 (25%), Positives = 25/47 (53%)
 Frame = -2

Query: 55   KTIKLQIWDTAGQERFRTITSSYYRGAHGIIVVYDVTDQESYANVKQ 101
            + ++L +WDTAGQE +  +    Y     I++ + +   +S  N+ +
Sbjct: 2729 QQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPE 2589
>18184
          Length = 558

 Score = 30.0 bits (66), Expect = 0.62,   Method: Compositional matrix adjust.
 Identities = 13/36 (36%), Positives = 21/36 (58%)
 Frame = -3

Query: 7   YLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIG 42
           YLF +LL G    G  CL+  F  +++   ++ST+G
Sbjct: 442 YLFYILLTGIVQFGYCCLVGTFPFNSFLAGFVSTVG 335
>31932
          Length = 437

 Score = 27.7 bits (60), Expect = 3.0,   Method: Compositional matrix adjust.
 Identities = 17/71 (23%), Positives = 34/71 (47%)
 Frame = -1

Query: 102 WLQEIDRYASENVNKLLVGNKSDLTTKKVVDNTTAKEFADSLGVPFLETSAKNATNVEQA 161
           W   ++      V  LL+GNKSDL  ++V  +       +   + + ETS K+ T ++++
Sbjct: 437 WTASVNWPYGSTVPCLLLGNKSDLGHREVEQDEIEDLCKEHDFLGWSETSVKDGTMIDES 258

Query: 162 FMTMAAEIKKR 172
              +  E+  +
Sbjct: 257 MNYLIEEMMAK 225
>28005
          Length = 753

 Score = 27.3 bits (59), Expect = 3.8,   Method: Compositional matrix adjust.
 Identities = 11/39 (28%), Positives = 20/39 (51%)
 Frame = -1

Query: 20  GKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIK 58
            K CL++      Y  S++S +GV F +   ++ G+  K
Sbjct: 363 AKHCLVMHRLGHLYVISHLSCVGVMFVLSVFDIIGRLCK 247
>06994
          Length = 429

 Score = 26.9 bits (58), Expect = 6.2,   Method: Compositional matrix adjust.
 Identities = 16/86 (18%), Positives = 33/86 (38%), Gaps = 32/86 (37%)
 Frame = +1

Query: 48  RTIELDGKTIKLQIWDTAG--------------------------------QERFRTITS 75
           + +E+DG+   L+I DTAG                                 E+F  +  
Sbjct: 172 KQVEVDGQQCMLEILDTAGTVHASHSNACVHGSLHAFVGTVTPLGRDALLNTEQFTAMRD 351

Query: 76  SYYRGAHGIIVVYDVTDQESYANVKQ 101
            Y +   G ++ Y +T Q ++ ++++
Sbjct: 352 LYMKNGQGFLLAYSITAQSTFNDLQE 429
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|24233554|ref|NP_683740.1| solute carrier family 1
(glial high affinity glutamate transporter), member 3 [Mus musculus]
         (543 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

19646                                                                 161   5e-40
26838                                                                 115   5e-26
32828                                                                  57   1e-08
12528                                                                  36   0.039
03021                                                                  31   1.2  
>19646
          Length = 731

 Score =  161 bits (408), Expect = 5e-40,   Method: Compositional matrix adjust.
 Identities = 77/131 (58%), Positives = 92/131 (70%)
 Frame = +2

Query: 370 PITFKCLEENNGVDKRITRFVLPVGATINMDGTALYEALAAIFIAQVNNFDLNFGQXXXX 429
           P+T  CL   N V++RI RFV P+GATINMDGTALYEA+AAIFIAQVN   L+       
Sbjct: 68  PVTMDCLVRKNNVNERIVRFVAPIGATINMDGTALYEAVAAIFIAQVNGISLSVADVIVV 247

Query: 430 XXXXXXXXXXXXXXPQAGLVTMVIVLTSVGLPTDDITLIIAVDWFLDRLRTTTNVLGDSL 489
                         PQAGLVTMVIVLT+V LPT+D+TLI+A+DWFLDR RT  NV GDS+
Sbjct: 248 SLTSTAAAIGAAGVPQAGLVTMVIVLTAVNLPTEDVTLILAIDWFLDRFRTAVNVWGDSV 427

Query: 490 GAGIVEHLSRH 500
           GAGI+ H+ R+
Sbjct: 428 GAGILNHIFRN 460
>26838
          Length = 787

 Score =  115 bits (287), Expect = 5e-26,   Method: Compositional matrix adjust.
 Identities = 50/99 (50%), Positives = 75/99 (75%)
 Frame = -1

Query: 242 NALGLVVFSMCFGFVIGNMKEQGQALREFFDSLNEAIMRLVAVIMWYAPLGILFLIAGKI 301
             LG++ F   FG +I NM+E+G+ + +FF  LNE IM+LVA++MWY+P+GI+FLI GKI
Sbjct: 298 QCLGIITFCTAFGILISNMRERGKIMMDFFTCLNEIIMKLVAMVMWYSPIGIMFLITGKI 119

Query: 302 VEMEDMGVIGGQLAMYTVTVIVGLLIHAVIVLPLLYFLV 340
           + ++D   +G  L MY VTV+ GL+IHAV++LP +YF++
Sbjct: 118 LSLDDPAKVGQLLGMYMVTVLTGLIIHAVVILPAIYFVI 2

 Score = 63.9 bits (154), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 39/120 (32%), Positives = 58/120 (48%), Gaps = 2/120 (1%)
 Frame = -2

Query: 96  VLPLIISSLVTGMAALDSK--ASGKMGMRAVVYYMXXXXXXXXXXXXXXXXXHPGKGTKE 153
           +LPLI+SS++TG+A LD++  A G  G   ++                          + 
Sbjct: 786 ILPLIVSSMITGLANLDARFRADGSAGHCVLLQLPHFLPSSWASSWWCPSTLETPPSRRG 607

Query: 154 NMYREGKIVQVTAADAFLDLIRNMFPPNLVEACFKQFKTSYEKRSFKVPIQSNETLLGAV 213
              R       T+ DAFLDLIRN+FP NL++ACF+  KT Y+   F +P    E +  A+
Sbjct: 606 WT*RRMIPKPPTSMDAFLDLIRNIFPDNLLQACFQHTKTVYQDDGFIIPKDLPENVTNAI 427
>32828
          Length = 643

 Score = 57.4 bits (137), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 32/124 (25%), Positives = 60/124 (48%)
 Frame = +2

Query: 388 RFVLPVGATINMDGTALYEALAAIFIAQVNNFDLNFGQXXXXXXXXXXXXXXXXXXPQAG 447
            FVLP+ A++N D +A++  L   ++AQV                             A 
Sbjct: 2   SFVLPLVASVNRDASAMFICLTCTYMAQVQG-SATVDTILLILILTSVGSLAIPSMHAAS 178

Query: 448 LVTMVIVLTSVGLPTDDITLIIAVDWFLDRLRTTTNVLGDSLGAGIVEHLSRHELKNRDV 507
           + T+V+++TS+GL   +I +++A++WF DRLRT +N    ++   +  H  +    +   
Sbjct: 179 MATVVMIVTSLGLHPANIGILMALEWFSDRLRTASNNYSHNVCCLVTWHFCKCSXNDPCP 358

Query: 508 EMGN 511
           E+G+
Sbjct: 359 EVGH 370
>12528
          Length = 928

 Score = 35.8 bits (81), Expect = 0.039,   Method: Compositional matrix adjust.
 Identities = 16/37 (43%), Positives = 21/37 (56%)
 Frame = +3

Query: 153 ENMYREGKIVQVTAADAFLDLIRNMFPPNLVEACFKQ 189
           + + R+G        DA LDLIRN FP NLV   F++
Sbjct: 12  DKIQRKGSSSDTKPLDALLDLIRNCFPDNLVTVAFER 122
>03021
          Length = 1073

 Score = 31.2 bits (69), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 17/47 (36%), Positives = 27/47 (57%)
 Frame = +2

Query: 462 TDDITLIIAVDWFLDRLRTTTNVLGDSLGAGIVEHLSRHELKNRDVE 508
           T  IT+I    +F+D   TT N+   SLG  +  H+ +H LKN+ ++
Sbjct: 257 TSSITMIENGIYFIDHF*TTLNIC--SLGTFLSVHVFKHTLKNKYIK 391
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|9506865|ref|NP_061342.1| intraflagellar transport
protein IFT20 [Mus musculus]
         (132 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

17348                                                                 158   5e-40
>17348
          Length = 774

 Score =  158 bits (400), Expect = 5e-40,   Method: Compositional matrix adjust.
 Identities = 82/132 (62%), Positives = 95/132 (71%)
 Frame = -3

Query: 1   MAKDILGEAGLHFDELNKLRVLDPEVTQQTVELKEECKDFVDKIGQFQKIVGGLIELVDQ 60
           MA + L +AGLHFDELNK+RVL+PEV QQT ELKEECKDFVDKIG+FQKIVG  IE+VD 
Sbjct: 766 MADEALAKAGLHFDELNKIRVLEPEVAQQTRELKEECKDFVDKIGEFQKIVGTFIEMVDS 587

Query: 61  LAKEAENEKMKAIGARNLLKSXXXXXXXXXXXXXXXXXXXKTQLERYRVEYEALCKVEAE 120
           +AKE E EKMKAIGARNLLKS                   + QLER R++Y+ L K E E
Sbjct: 586 VAKEVEKEKMKAIGARNLLKSMAKQREAQQQQLQALITEKRMQLERLRIQYDGLQKEEGE 407

Query: 121 QNEFIDQFIFQK 132
           QNEF++Q I QK
Sbjct: 406 QNEFLEQLISQK 371
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|225543420|ref|NP_666236.3| Rho GTPase activating
protein 1 isoform 2 [Mus musculus]
         (439 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

26617                                                                 161   6e-40
17428                                                                  87   9e-18
11263                                                                  82   1e-16
17558                                                                  79   4e-15
12558                                                                  69   5e-12
18151                                                                  64   1e-10
20879                                                                  47   1e-09
11945                                                                  50   2e-06
30765                                                                  39   0.003
21189                                                                  36   0.034
19079                                                                  33   0.21 
20626                                                                  28   5.3  
>26617
          Length = 609

 Score =  161 bits (407), Expect = 6e-40,   Method: Compositional matrix adjust.
 Identities = 72/114 (63%), Positives = 89/114 (78%)
 Frame = +2

Query: 64  YYDIARHQIVEVAGDDKYGRKIIVFSACRMPPSHQLDHSKLLGYLKHTLDQYVESDYTLL 123
           + D+ R+ IVEVAGDD YGRK+IV SAC++P +   DH +LL Y+KHTLD+YVE DY L+
Sbjct: 236 FIDVERYGIVEVAGDDLYGRKVIVVSACKLPSNTTFDHQRLLDYIKHTLDKYVEQDYVLV 415

Query: 124 YLHHGLTSDNKPSLSWLRDAYREFDRKYKKNIKALYIVHPTMFIKTLLILFKPL 177
           Y H+GL S NKP LSWL  AYRE +RKYKKN+K LY+VHPT FIK L  +F+PL
Sbjct: 416 YFHYGLNSRNKPKLSWLLQAYRELNRKYKKNLKTLYLVHPTSFIKVLWNIFRPL 577
>17428
          Length = 623

 Score = 87.4 bits (215), Expect = 9e-18,   Method: Compositional matrix adjust.
 Identities = 47/128 (36%), Positives = 76/128 (59%), Gaps = 1/128 (0%)
 Frame = +1

Query: 278 EGIFRRSANTQVVREVQQKYNMGLPVDFDQY-NELHLPAVILKTFLRELPEPLLTFDLYP 336
           EG+FR S  +    +++  ++  L VD +++ N+ +  A ++K +LRELPEP+LTFDLYP
Sbjct: 1   EGLFRFSRISFKDEKLKACFDARL-VDMEEFSNDPNTVAGVMKQYLRELPEPMLTFDLYP 177

Query: 337 HVVGFLNIDESQRVEVTQQVLQTLPEENYQVLHFLTAFLVQISAHCDQNKMTNTNLAVVF 396
             +    +   Q+ +    ++  LP  N+    +L  FL  ++     NKMT +NLA+V 
Sbjct: 178 DFMRAAQLGHDQKCQSLYTLVNRLPPSNFNNFRYLIKFLALLAEKSHVNKMTPSNLAIVM 357

Query: 397 GPNLLWAK 404
           GPNLLWA+
Sbjct: 358 GPNLLWAR 381
>11263
          Length = 715

 Score = 81.6 bits (200), Expect(2) = 1e-16,   Method: Compositional matrix adjust.
 Identities = 38/90 (42%), Positives = 61/90 (67%), Gaps = 1/90 (1%)
 Frame = +2

Query: 127 HGLTSDNK-PSLSWLRDAYREFDRKYKKNIKALYIVHPTMFIKTLLILFKPLISFKFGRK 185
           HG T   + PS +WL+  Y   D + KKN+KALY+VHPT++IKT++++ +P IS KF  K
Sbjct: 104 HGATPRRQMPSFTWLKRCYHGIDXRLKKNLKALYLVHPTLWIKTVVMMTRPFISAKFSSK 283

Query: 186 IFYVNYLSELSEHVKLEQLGIPRQVLKYDD 215
           + +V  L++L + + +E + +P  V +YDD
Sbjct: 284 LQFVRTLNDLRQMIPMEYVYVPDIVQRYDD 373

 Score = 23.1 bits (48), Expect(2) = 1e-16,   Method: Compositional matrix adjust.
 Identities = 12/32 (37%), Positives = 19/32 (59%)
 Frame = +3

Query: 92  RMPPSHQLDHSKLLGYLKHTLDQYVESDYTLL 123
           R   S+ ++H  L  Y+ HTLD+ V  DY ++
Sbjct: 9   RKDYSYVMNH--LFHYVIHTLDELVADDYMIV 98
>17558
          Length = 671

 Score = 79.0 bits (193), Expect = 4e-15,   Method: Compositional matrix adjust.
 Identities = 57/199 (28%), Positives = 98/199 (49%), Gaps = 3/199 (1%)
 Frame = +3

Query: 242 FGVSLQHLQEKSPGQDPIPIVLRETVAYLQAHALTTEGIFRRSANTQVVREVQQKYNMG- 300
           FG SL+   E + G++ IP++++  +  +  + L  +G+FR S     +   +  +  G 
Sbjct: 57  FGGSLEEYIEAT-GEE-IPLIIKGCIRVINLYGLHHQGVFRVSGAQVEINHFKNVFESGD 230

Query: 301 -LPVDFDQYNELHLPAVILKTFLRELPEPLLTFDLYPHVVGFLN-IDESQRVEVTQQVLQ 358
              VD    ++++  A +LK + REL EPL    L+  +V      D  +R+E  + +L 
Sbjct: 231 DALVDVVDASDMNSIAGVLKLYFRELREPLFPLHLFDALVECTRENDVHRRLERIKDLLA 410

Query: 359 TLPEENYQVLHFLTAFLVQISAHCDQNKMTNTNLAVVFGPNLLWAKDAAITLKAINPINT 418
           TLP   + V+ +L AFL  +S + D+N M   NLA+ FGP LL        +        
Sbjct: 411 TLPRSVFVVMRYLFAFLNHLSEYSDENMMDPYNLAICFGPTLLPIPPDRDQVVLPGLRQR 590

Query: 419 FTKFLLDHQGELFPSTDAQ 437
             K ++ HQ E+FP+   +
Sbjct: 591 IIKTIIVHQEEIFPNDGGE 647
>12558
          Length = 720

 Score = 68.6 bits (166), Expect = 5e-12,   Method: Compositional matrix adjust.
 Identities = 46/163 (28%), Positives = 84/163 (51%), Gaps = 9/163 (5%)
 Frame = -1

Query: 278 EGIFRRSANTQVVREVQQKYNMGLPVDFD---QY-NELHLPAVILKTFLRELPEPLLTFD 333
           +G++R S  T  +++++  ++     +     QY  ++H  + +LK + RELP PLLT+ 
Sbjct: 714 DGLYRLSGVTSNIQKLRVAFDEDQAPELSDNVQYLQDIHSISSLLKMYFRELPNPLLTYQ 535

Query: 334 LYPHVVGFLNIDESQRVEVTQQVLQTLPEENYQVLHFLTAFLVQISAHCDQNKMTNTNLA 393
           LY      +  DE  R+     V+Q LP  +Y+ L +L   L  ++++  Q  M + NLA
Sbjct: 534 LYTQFADAVK-DEDNRLLRIHDVVQQLPPPHYRTLEYLVRHLACVASYGLQTGMHSKNLA 358

Query: 394 VVFGPNLLWAKD-----AAITLKAINPINTFTKFLLDHQGELF 431
           +V+ PNLL +K+      A  L+ +      T+ L+ +   +F
Sbjct: 357 IVWAPNLLRSKELEQGGGAAALRGVGIQAVVTECLICYCDLIF 229
>18151
          Length = 1032

 Score = 64.3 bits (155), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 33/104 (31%), Positives = 54/104 (51%)
 Frame = +2

Query: 66  DIARHQIVEVAGDDKYGRKIIVFSACRMPPSHQLDHSKLLGYLKHTLDQYVESDYTLLYL 125
           DIA  + +  +G D++GR +IVF       +   D  + L Y+   +D  V+S Y ++Y 
Sbjct: 410 DIASLRCLYRSGVDRHGRPVIVFVGANFS-ARDCDMDRALLYMVKVMDTVVDSPYVVVYF 586

Query: 126 HHGLTSDNKPSLSWLRDAYREFDRKYKKNIKALYIVHPTMFIKT 169
           H    S N P +++L++AY   D +YKKN+K        M +K 
Sbjct: 587 HTLTNSSNHPPMNFLKEAYSRLDNRYKKNLKKFLYYSSNMVVKA 718
>20879
          Length = 1019

 Score = 46.6 bits (109), Expect(2) = 1e-09,   Method: Compositional matrix adjust.
 Identities = 25/88 (28%), Positives = 46/88 (52%), Gaps = 1/88 (1%)
 Frame = -2

Query: 253 SPGQDP-IPIVLRETVAYLQAHALTTEGIFRRSANTQVVREVQQKYNMGLPVDFDQYNEL 311
           +P Q P IP ++      ++   L+  GI+R   + +  +++++K+  G   +     ++
Sbjct: 586 APTQRPMIPRLVVNCANEIERRGLSEVGIYRVPGSDRDSKDLKEKFLKGKSPNLSNIIDI 407

Query: 312 HLPAVILKTFLRELPEPLLTFDLYPHVV 339
           H     LK FLR L EPL+TF L+P + 
Sbjct: 406 HTVCGCLKDFLRNLKEPLVTFALWPQLC 323

 Score = 33.5 bits (75), Expect(2) = 1e-09,   Method: Compositional matrix adjust.
 Identities = 23/69 (33%), Positives = 32/69 (46%), Gaps = 3/69 (4%)
 Frame = -1

Query: 333 DLYPH---VVGFLNIDESQRVEVTQQVLQTLPEENYQVLHFLTAFLVQISAHCDQNKMTN 389
           DL P    V G  N ++    ++  + +  LP  N   L FL   L ++S      KM  
Sbjct: 350 DLCPLAXIVRGAENSNQQMSYDIVCEAINNLPTANRDTLAFLVQHLQKVSES-TATKMPA 174

Query: 390 TNLAVVFGP 398
           +NLA VFGP
Sbjct: 173 SNLAKVFGP 147
>11945
          Length = 1161

 Score = 50.1 bits (118), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 35/99 (35%), Positives = 51/99 (51%), Gaps = 1/99 (1%)
 Frame = -1

Query: 315 AVILKTFLRELPEPLLTFDLYPHVVGFLNIDES-QRVEVTQQVLQTLPEENYQVLHFLTA 373
           A +LK FLRELP PLLT+D         NI ++ ++++    ++  LP E+  VL  L  
Sbjct: 312 AALLKQFLRELPTPLLTYDYLEAFPQVENIPKTLEQLKALNLLVLLLPTEHRDVLKVLLR 133

Query: 374 FLVQISAHCDQNKMTNTNLAVVFGPNLLWAKDAAITLKA 412
           FL  I +H D NKM   N+ ++    L  A      +KA
Sbjct: 132 FLRNIVSHSDTNKMGLNNICMIMAQILFIAPAGKGKVKA 16
>30765
          Length = 635

 Score = 39.3 bits (90), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 30/94 (31%), Positives = 48/94 (51%), Gaps = 5/94 (5%)
 Frame = +2

Query: 242 FGVSLQHLQEKSPGQDPIPIVLRETVAYLQAHALTTEGIFRRSANTQVVREVQQ-KYNMG 300
           FG +LQ   +K     P+P  + E +A ++   L  +G++R S N   + E+Q+ +Y + 
Sbjct: 278 FGSTLQAQCDKDKA--PVPNFVLECIAAVEKKGLDQDGLYRVSGN---LAEIQRLRYVVD 442

Query: 301 LPVDF----DQYNELHLPAVILKTFLRELPEPLL 330
              D     DQ++ +H     LK F REL EPL 
Sbjct: 443 KDDDHNLTEDQWD-IHTLTGALKLFFRELKEPLF 541
>21189
          Length = 461

 Score = 35.8 bits (81), Expect = 0.034,   Method: Compositional matrix adjust.
 Identities = 30/95 (31%), Positives = 49/95 (51%), Gaps = 2/95 (2%)
 Frame = +3

Query: 242 FGVSLQHLQEKSPGQDPIPIVLRETVAYLQAHALTTEGIFRRSANTQVVREVQQKYNMGL 301
           FGV    + +++ GQ P+P  +   + YL+  +    GIFR+S     + +++       
Sbjct: 177 FGVPFTVILQRT-GQ-PLPQCVLYAMRYLRKTSHDAVGIFRKSGVRSRIHKLRDMVE-SC 347

Query: 302 P--VDFDQYNELHLPAVILKTFLRELPEPLLTFDL 334
           P  V+FD+     + A +LK + RELPE LLT  L
Sbjct: 348 PDTVNFDELQPYDV-ADLLKQYFRELPECLLTTKL 449
>19079
          Length = 436

 Score = 33.1 bits (74), Expect = 0.21,   Method: Composition-based stats.
 Identities = 20/69 (28%), Positives = 36/69 (52%), Gaps = 1/69 (1%)
 Frame = -1

Query: 303 VDFDQYNELHLPAVILKTFLRELPEPLLTFDLYPHVVGFL-NIDESQRVEVTQQVLQTLP 361
           VD    +E++  A +LK + REL EPL    L+  +V     I   +R++  + +L +LP
Sbjct: 325 VDVTDASEMNSVAGVLKLYFRELREPLFPLHLFDALVECTREISVQRRLDSIRDLLASLP 146

Query: 362 EENYQVLHF 370
              + V+ +
Sbjct: 145 RAIFVVMRW 119
>20626
          Length = 396

 Score = 28.5 bits (62), Expect = 5.3,   Method: Composition-based stats.
 Identities = 14/36 (38%), Positives = 21/36 (58%)
 Frame = +2

Query: 304 DFDQYNELHLPAVILKTFLRELPEPLLTFDLYPHVV 339
           D D+Y+ L  P V+ +TFL  L   ++T   YP V+
Sbjct: 164 DLDKYDHLDFPGVVPRTFLGPL---IVTVTAYPAVL 262
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|30424792|ref|NP_780394.1| hydroxysteroid
dehydrogenase like 1 [Mus musculus]
         (330 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

18041                                                                 160   7e-40
03060                                                                  57   7e-09
05690                                                                  43   2e-04
18534                                                                  42   4e-04
30783                                                                  41   7e-04
28229                                                                  40   0.002
27168                                                                  35   0.035
36857                                                                  34   0.10 
25543                                                                  31   0.89 
25434                                                                  29   2.1  
19105                                                                  29   2.2  
>18041
          Length = 547

 Score =  160 bits (405), Expect = 7e-40,   Method: Compositional matrix adjust.
 Identities = 83/183 (45%), Positives = 118/183 (64%), Gaps = 3/183 (1%)
 Frame = -2

Query: 74  GATDGIGKAYAEELASHGLNVILISQEEEKLQAAAKHIADTYRVETLVLVADFSRGREIY 133
           G+TDGIGK +A +LA  GL+++LIS+  EKL A AK I D ++V   V+ ADF +  +IY
Sbjct: 546 GSTDGIGKCFALQLAEKGLDIVLISRNPEKLSAVAKEIVDQHKVSVKVITADF-KNADIY 370

Query: 134 APIREALRDRDIGILVNDVGAFYP-YPQYFSQVP--EDTLWDIVNVNIAAASLMVHIVLP 190
             I+  L   DIGILVN+VG      P YF +    E    DI+NVNI A   M  IVLP
Sbjct: 369 DNIKRQLTGLDIGILVNNVGMLNRRNPGYFCEADDFEQFHQDIINVNILACVQMTGIVLP 190

Query: 191 GMVERKKGAIVTVSSGSCCKPTPQLAAFSASKAYLDHFSRALQYEYASKGIFVQSLIPFY 250
            M+ERK+G I+ ++SG+  +P P  + +S +KA++ HF++AL  EY+S+G+ +Q LIP  
Sbjct: 189 EMLERKRGLIINIASGAAIRPLPFFSVYSGTKAFISHFTQALNMEYSSQGVTIQLLIPNL 10

Query: 251 VTS 253
           V +
Sbjct: 9   VAT 1
>03060
          Length = 1893

 Score = 57.4 bits (137), Expect = 7e-09,   Method: Compositional matrix adjust.
 Identities = 55/211 (26%), Positives = 93/211 (44%), Gaps = 5/211 (2%)
 Frame = -1

Query: 49   RLHFIPRLGSRPDLIKQYGRWAVISGATDGIGKAYAEELASHGLNVILISQEEEKLQAAA 108
            R+    +L +R   I+  G+  +++GA+ G+GKA A+    HG  VIL  +  E+L A  
Sbjct: 1737 RIRTFIKLRTRAADIQ--GKVVLVTGASSGLGKACAKVFHQHGCQVILAGRSVERLNAVK 1564

Query: 109  KHI----ADTYRVETLVLVADFSRGREIYAPIREALRD-RDIGILVNDVGAFYPYPQYFS 163
             ++     +    E  VL  D      +      A+     + +++N+ G  Y      +
Sbjct: 1563 DYLTKSEGEVKACEPSVLAMDLEDLNSLQQLAERAVELFGKVDVVINNAGISYRGCIEDT 1384

Query: 164  QVPEDTLWDIVNVNIAAASLMVHIVLPGMVERKKGAIVTVSSGSCCKPTPQLAAFSASKA 223
             +  D    ++ VN      ++  +LP M  R  G IV +SS       P  +A+SASK 
Sbjct: 1383 SIQVD--QKLMAVNYFGHVALIKGLLPHMQARNSGHIVGISSVQGKISIPYRSAYSASKH 1210

Query: 224  YLDHFSRALQYEYASKGIFVQSLIPFYVTSS 254
             L  F   L+ E +   I V  L P Y+ ++
Sbjct: 1209 ALQAFFDCLRAELSCTKIKVSLLSPGYIKTN 1117
>05690
          Length = 1192

 Score = 42.7 bits (99), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 46/198 (23%), Positives = 81/198 (40%), Gaps = 11/198 (5%)
 Frame = +2

Query: 62  LIKQYGRWAVISGATDGIGKAYAEELASHGLNVILI-----SQEEEKLQAAAKH-----I 111
           L+   G+   I+G   G+G   A  L   G+ V         + E+ L+A          
Sbjct: 158 LLPAEGKAVFITGCDAGLGHLLAIHLDKLGVKVFAGCLFPGGEGEQTLKAKCSQRLCTVP 337

Query: 112 ADTYRVETLVLVADFSRGREIYAPIREALRDRDIGILVNDVGAFY-PYPQYFSQVPEDTL 170
            D   +E +   AD          ++  L  +++  +VN+ G  +    +   Q   D +
Sbjct: 338 LDVCSLEIVTTAAD---------TVKRELDGQELWGVVNNAGIMHIGCLEVMGQADVDKI 490

Query: 171 WDIVNVNIAAASLMVHIVLPGMVERKKGAIVTVSSGSCCKPTPQLAAFSASKAYLDHFSR 230
            D   VN      ++   LP  + R +G +V V+S +   P P  A + ASKA +   + 
Sbjct: 491 LD---VNYRGQVNVIRAFLP-FLRRSRGRLVNVASNTGIAPVPYHAVYCASKAAVAALTE 658

Query: 231 ALQYEYASKGIFVQSLIP 248
           +L+ E    G+ V ++IP
Sbjct: 659 SLRLELQPFGVRVSTIIP 712
>18534
          Length = 406

 Score = 41.6 bits (96), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 33/132 (25%), Positives = 60/132 (45%), Gaps = 4/132 (3%)
 Frame = -2

Query: 123 VADFSRGREIYAPIREALRD-RDIGILVNDVGAFYPYPQYFSQVPEDTLWDIVNVNIAAA 181
           V D S   +IY    + + D   + +L+N+ G     P  F ++ +  + +  N+NI + 
Sbjct: 390 VVDISDREQIYQRAAQVIDDVGHVDVLINNAGIVCCKP--FWELHDRVIQNTYNINIISH 217

Query: 182 SLMVHIVLPGMVERKKGAIVTVSSGSCCKPTPQLAAFSASKAYLDHFSRALQYEYASKG- 240
              V   LP M+   +G IVTV S +    T   + ++A+K     F  +L  +  + G 
Sbjct: 216 YWTVKAFLPHMMRHNRGHIVTVGSVTGMLGTYGCSDYAATKYACIGFHESLLTDLKAHGY 37

Query: 241 --IFVQSLIPFY 250
             I +  + P+Y
Sbjct: 36  DQIHMSLICPYY 1
>30783
          Length = 765

 Score = 40.8 bits (94), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 22/57 (38%), Positives = 31/57 (54%)
 Frame = +1

Query: 197 KGAIVTVSSGSCCKPTPQLAAFSASKAYLDHFSRALQYEYASKGIFVQSLIPFYVTS 253
           KG IV VSS    +P  ++  +  SKA +D F++ L  E A  G+ V S+ P  V S
Sbjct: 178 KGCIVNVSSICASRPMAEVGVYCMSKAAMDMFTQCLALELAPHGVRVNSVNPGSVVS 348
>28229
          Length = 633

 Score = 39.7 bits (91), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 23/66 (34%), Positives = 39/66 (59%)
 Frame = -1

Query: 189 LPGMVERKKGAIVTVSSGSCCKPTPQLAAFSASKAYLDHFSRALQYEYASKGIFVQSLIP 248
           LP ++ + KGA+V VSS +     P   ++  SKA LD F++ +  E A +G+ V S+ P
Sbjct: 297 LPHLL-KTKGAVVNVSSCAGICHFPGALSYGISKAALDQFTKIVSLELAPQGVRVNSVNP 121

Query: 249 FYVTSS 254
            +V ++
Sbjct: 120 GFVVTN 103
>27168
          Length = 665

 Score = 35.4 bits (80), Expect = 0.035,   Method: Compositional matrix adjust.
 Identities = 20/47 (42%), Positives = 25/47 (53%)
 Frame = +3

Query: 66  YGRWAVISGATDGIGKAYAEELASHGLNVILISQEEEKLQAAAKHIA 112
           +GR A+I+GA  GIG   A  LA HG  +IL  +     Q A   IA
Sbjct: 183 HGRVALITGANCGIGFETARSLALHGCEIILACRNLATAQEAIDRIA 323
>36857
          Length = 697

 Score = 33.9 bits (76), Expect = 0.10,   Method: Compositional matrix adjust.
 Identities = 21/66 (31%), Positives = 34/66 (51%), Gaps = 3/66 (4%)
 Frame = +3

Query: 191 GMVERKKGA-IVTVSSGSCCKPTPQLAAFSASKAYLDHFSR--ALQYEYASKGIFVQSLI 247
           G  + ++GA I+ +SS    +P P    +  +KA +  FSR  A   +Y   GI V +L 
Sbjct: 237 GGTKGERGASIINISSAGGLRPQPVGPVYCGTKAGVMMFSRSVAAHKDYIDNGIRVNTLC 416

Query: 248 PFYVTS 253
           P +V +
Sbjct: 417 PAFVDT 434
>25543
          Length = 518

 Score = 30.8 bits (68), Expect = 0.89,   Method: Compositional matrix adjust.
 Identities = 14/35 (40%), Positives = 22/35 (62%)
 Frame = -1

Query: 37  SITVICDFYSLVRLHFIPRLGSRPDLIKQYGRWAV 71
           S T +C+F S  ++HF P+L  +P LI Q G+  +
Sbjct: 113 SCTTLCNFLSKHKIHFQPQL-IQPQLIPQTGKTVL 12
>25434
          Length = 1073

 Score = 29.3 bits (64), Expect = 2.1,   Method: Compositional matrix adjust.
 Identities = 24/94 (25%), Positives = 44/94 (46%), Gaps = 7/94 (7%)
 Frame = -2

Query: 109 KHIADTYRVETLVLVADFSRGREI------YAPIREALRDRDIGILVNDVGAFYPYPQYF 162
           K++ + +R+ T   V DF R R I      YA +  A   +D+     D   ++P   + 
Sbjct: 712 KNMCNEFRLVTFWTVKDFPRNRGIKLTG*EYAFVA*AYVCQDLA--SEDKPLYWPSQAFV 539

Query: 163 SQVPE-DTLWDIVNVNIAAASLMVHIVLPGMVER 195
           +   +  T+W  VNV I  +++ + I LP  + +
Sbjct: 538 NDFRKFTTMWC*VNVYILPSNIQILIXLPCXIAK 437
>19105
          Length = 455

 Score = 29.3 bits (64), Expect = 2.2,   Method: Compositional matrix adjust.
 Identities = 14/42 (33%), Positives = 21/42 (50%)
 Frame = +3

Query: 133 YAPIREALRDRDIGILVNDVGAFYPYPQYFSQVPEDTLWDIV 174
           YA       + D+GILV+ +  F+  P+   Q  ED L D +
Sbjct: 141 YAETTSIYGNHDVGILVDKLEQFFKTPETALQTFEDKLGDFI 266
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31560778|ref|NP_083770.2| RAB30, member RAS oncogene
family [Mus musculus]
         (203 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

34468                                                                 159   7e-40
08428                                                                 145   7e-36
32723                                                                 134   3e-32
14456                                                                 115   1e-26
07465                                                                 111   2e-25
26083                                                                 107   4e-24
33374                                                                 104   3e-23
05468                                                                 103   5e-23
17511                                                                 103   6e-23
33794                                                                 100   3e-22
01972                                                                  87   6e-22
30760                                                                  98   3e-21
33380                                                                  91   4e-19
11257                                                                  87   4e-18
13901                                                                  87   4e-18
27191                                                                  85   2e-17
13750                                                                  85   2e-17
01398                                                                  81   3e-16
35581                                                                  78   3e-15
19006                                                                  77   4e-15
07580                                                                  77   4e-15
13745                                                                  75   3e-14
11728                                                                  72   1e-13
26536                                                                  70   7e-13
01095                                                                  69   1e-12
12339                                                                  68   2e-12
34359                                                                  67   7e-12
34597                                                                  64   3e-11
29380                                                                  64   5e-11
19656                                                                  60   5e-10
00858                                                                  59   2e-09
14775                                                                  57   7e-09
09204                                                                  53   7e-08
14119                                                                  53   8e-08
31291                                                                  50   6e-07
10708                                                                  37   7e-07
00552                                                                  49   2e-06
25618                                                                  48   3e-06
19046                                                                  46   1e-05
24619                                                                  44   3e-05
33605                                                                  44   3e-05
08153                                                                  42   3e-04
25796                                                                  41   3e-04
09827                                                                  40   6e-04
18509                                                                  39   0.001
31928                                                                  36   0.012
10862                                                                  33   0.056
12443                                                                  33   0.070
06994                                                                  32   0.16 
06169                                                                  30   0.62 
31932                                                                  29   1.6  
00235                                                                  27   7.6  
>34468
          Length = 1502

 Score =  159 bits (402), Expect = 7e-40,   Method: Compositional matrix adjust.
 Identities = 79/187 (42%), Positives = 126/187 (67%), Gaps = 5/187 (2%)
 Frame = +1

Query: 9   LFKIVLIGNAGVGKTCLVRRFTQGLFPPGQGATIGVDFMIKTVEINGEKVKLQIWDTAGQ 68
           +FKI++IG++ VGKTCL  RF  G FP    ATIGVDF  K+++++ E +KLQ+WDTAGQ
Sbjct: 493 IFKIIVIGDSNVGKTCLTYRFCLGKFPDKTEATIGVDFREKSIQVDSEHLKLQLWDTAGQ 672

Query: 69  ERFR-SITQSYYRSANALILTYDITCEESFRCLPEWLREIEQYASNKVIT-VLVGNKIDL 126
           ERFR S+ Q YYR+ +A++  YD+T   SF  +P W+ E +++   K I  +LVGNK D+
Sbjct: 673 ERFRKSMVQHYYRNVHAVVFVYDMTKMSSFENMPAWIEECDRHNLTKYIPRILVGNKCDV 852

Query: 127 AERREVSQQRAEEFSEAQDMYYLETSAKE---SDNVEKLFLDLACRLISEARQNTLVNNV 183
            ER  V+   A++F++A +M   ETSAK+   +++V+ +F+ +A +L  +  +  +  ++
Sbjct: 853 VERIAVNTNLAQKFADAHNMPLFETSAKDDEKANHVDAIFMTVAHKL--KXSKPMMPAHL 1026

Query: 184 SSPLPGE 190
           S  +PG+
Sbjct: 1027SEMVPGD 1047
>08428
          Length = 1109

 Score =  145 bits (367), Expect = 7e-36,   Method: Compositional matrix adjust.
 Identities = 70/183 (38%), Positives = 111/183 (60%)
 Frame = -3

Query: 1    MSMEDYDFLFKIVLIGNAGVGKTCLVRRFTQGLFPPGQGATIGVDFMIKTVEINGEKVKL 60
            M M D     K+ L+G++GVGK+ +V RF  G + P Q +TIG  FM K++ ++G   + 
Sbjct: 1083 MQMRD----VKVCLLGDSGVGKSSIVLRFVTGSYRPSQESTIGASFMSKSLVVDGAGYRF 916

Query: 61   QIWDTAGQERFRSITQSYYRSANALILTYDITCEESFRCLPEWLREIEQYASNKVITVLV 120
            QIWDTAGQE+FR++   YYR A A ++ YD+T   +F+ +  W++E+  +    ++  + 
Sbjct: 915  QIWDTAGQEKFRALAPMYYRGAAAAVIVYDVTRPRTFKSVKSWIQELRSFGPPNIVLAIA 736

Query: 121  GNKIDLAERREVSQQRAEEFSEAQDMYYLETSAKESDNVEKLFLDLACRLISEARQNTLV 180
            GNK DL E REV ++ A+E++ +    + ETSA  + NVE++F +LA +L  E       
Sbjct: 735  GNKCDLEELREVVEKDAQEYASSISAIFGETSAMTAVNVEEMFTELARQLPPEEDNPHPS 556

Query: 181  NNV 183
            N V
Sbjct: 555  NTV 547
>32723
          Length = 384

 Score =  134 bits (337), Expect = 3e-32,   Method: Compositional matrix adjust.
 Identities = 66/112 (58%), Positives = 85/112 (75%)
 Frame = +2

Query: 68  QERFRSITQSYYRSANALILTYDITCEESFRCLPEWLREIEQYASNKVITVLVGNKIDLA 127
           QERFRSITQSYYRSANALIL YD+  ++S+  LP+W+ EIE YA  KV+  LVGNKID  
Sbjct: 2   QERFRSITQSYYRSANALILVYDVCSQQSYESLPQWIHEIELYAGTKVLAFLVGNKIDQT 181

Query: 128 ERREVSQQRAEEFSEAQDMYYLETSAKESDNVEKLFLDLACRLISEARQNTL 179
           ++RE+     +EF+E  +M +LETSAKE+DNVEKLF  +A +L ++A Q TL
Sbjct: 182 DKREIPTHIGKEFAERYEMRFLETSAKEADNVEKLFSTIAYQLTAQA-QGTL 334
>14456
          Length = 1867

 Score =  115 bits (287), Expect = 1e-26,   Method: Compositional matrix adjust.
 Identities = 79/203 (38%), Positives = 108/203 (53%), Gaps = 12/203 (5%)
 Frame = -1

Query: 10   FKIVL---IGNAGVGKTCLVRRFTQGLFPPGQGATIGVDFMIKTVEINGEKVKLQIWDTA 66
             KI L   +   GVGK+ L+ RF    F      TIGV+F+ K V ++ E   +QIWDTA
Sbjct: 1147 LKITLDKQLKQGGVGKSSLMNRFVSNKFDAQSFHTIGVEFLNKDVVVDDETYTMQIWDTA 968

Query: 67   GQERFRSITQSYYRSANALILTYDITCEESFRCLPEWLREIEQYAS-NKVIT---VLVGN 122
            GQERF+S+   +YR A+  +LT+ +   +SFR L  W +E   YA     +T   V++GN
Sbjct: 967  GQERFKSLRTPFYRGADCCLLTFSVDSMQSFRNLSMWRKEFLYYADIQDGVTFPFVVLGN 788

Query: 123  KIDLAERREVSQQRAEEFSEAQ-DMYYLETSAKESDNVEKLFLDLACRLISEARQNTLV- 180
            KID+ E R+V+ + A  +  A  +  Y ETSAK++ NVEK FL    RL     Q  +  
Sbjct: 787  KIDV-EGRQVTNEEARSWCTANSNAPYFETSAKDATNVEKAFLAAVQRLREVEDQQEVKT 611

Query: 181  ---NNVSSPLPGEGKSISYLTCC 200
               N V       GKS S   CC
Sbjct: 610  AHGNTVDLNRAARGKSSS---CC 551
>07465
          Length = 1103

 Score =  111 bits (278), Expect = 2e-25,   Method: Compositional matrix adjust.
 Identities = 58/169 (34%), Positives = 98/169 (57%)
 Frame = +3

Query: 23  TCLVRRFTQGLFPPGQGATIGVDFMIKTVEINGEKVKLQIWDTAGQERFRSITQSYYRSA 82
           + +++R+ +G+F      TIGVDF+ + +E+ GE V+L +WDTAGQE F +IT++YYR A
Sbjct: 240 SSMIQRYCKGIFTKDYKKTIGVDFLERQIEVGGEDVRLMLWDTAGQEEFDAITKAYYRGA 419

Query: 83  NALILTYDITCEESFRCLPEWLREIEQYASNKVITVLVGNKIDLAERREVSQQRAEEFSE 142
            A +L +     +SF  L  W R++E     ++  V+V NKIDL +   V  + AE  ++
Sbjct: 420 QACVLAFSTVDRDSFEALETWKRKVEDEVG-EIGMVIVQNKIDLIDDAVVRPEEAENLAK 596

Query: 143 AQDMYYLETSAKESDNVEKLFLDLACRLISEARQNTLVNNVSSPLPGEG 191
              + +  TS KE+ NV+++F  LA + + +        N++    G+G
Sbjct: 597 KLRLRFYRTSVKENMNVDEVFRYLADKYLHQLNTGMDEVNLTPQKIGQG 743
>26083
          Length = 432

 Score =  107 bits (267), Expect = 4e-24,   Method: Compositional matrix adjust.
 Identities = 50/114 (43%), Positives = 71/114 (62%)
 Frame = +1

Query: 10  FKIVLIGNAGVGKTCLVRRFTQGLFPPGQGATIGVDFMIKTVEINGEKVKLQIWDTAGQE 69
           FK+V +G   VGKT L+ RF    F     ATIG+DF+ KT+ +    ++LQ+WDTAGQE
Sbjct: 79  FKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTIRLQLWDTAGQE 258

Query: 70  RFRSITQSYYRSANALILTYDITCEESFRCLPEWLREIEQYASNKVITVLVGNK 123
           RFRS+  SY R ++  ++ YDIT   SF    +W+ ++     + VI +LVGNK
Sbjct: 259 RFRSLIPSYIRDSSVAVVVYDITNANSFHQTSKWIDDVRTERGSDVIIMLVGNK 420
>33374
          Length = 489

 Score =  104 bits (259), Expect = 3e-23,   Method: Compositional matrix adjust.
 Identities = 48/117 (41%), Positives = 76/117 (64%)
 Frame = +1

Query: 46  FMIKTVEINGEKVKLQIWDTAGQERFRSITQSYYRSANALILTYDITCEESFRCLPEWLR 105
           F+ +TV ++   VK +IWDTAGQER+ S+   YYR A A I+ YDIT +++F     W++
Sbjct: 139 FLTQTVCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNQDTFGRAKTWVK 318

Query: 106 EIEQYASNKVITVLVGNKIDLAERREVSQQRAEEFSEAQDMYYLETSAKESDNVEKL 162
           E+++ AS  ++  L GNK DLA +R V  + A+ ++E   + ++ETSAK + NV  +
Sbjct: 319 ELQRQASPNIVIALAGNKADLANKRMVEFEEAQAYAEENSLLFMETSAKTAMNVNDI 489

 Score = 39.3 bits (90), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 30/85 (35%), Positives = 41/85 (48%)
 Frame = +2

Query: 10  FKIVLIGNAGVGKTCLVRRFTQGLFPPGQGATIGVDFMIKTVEINGEKVKLQIWDTAGQE 69
           FK+VL+G + VGK+ LV RF +G F   Q +TIG  F ++           Q      Q 
Sbjct: 32  FKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAF*LR-----------QFVLMTQQS 178

Query: 70  RFRSITQSYYRSANALILTYDITCE 94
             RS TQ   R  NA+ + +  T E
Sbjct: 179 SLRSGTQ---RVKNAITV*HQCTTE 244
>05468
          Length = 1558

 Score =  103 bits (257), Expect = 5e-23,   Method: Compositional matrix adjust.
 Identities = 65/210 (30%), Positives = 111/210 (52%), Gaps = 13/210 (6%)
 Frame = -3

Query: 4    EDYDFLFKIVLIGNAGVGKTCLVRRFTQGLFPPGQGATIGVDFMIKTVEINGEK-VKLQI 62
            E  + L+KI++IG  G GKT +++R+    F     ATIGVDF +K +  + +  ++LQ+
Sbjct: 1556 EKKEHLYKILVIGELGTGKTSIIKRYVHQFFSQHYRATIGVDFALKVLNWDADTLIRLQL 1377

Query: 63   WDTAGQERFRSITQSYYRSANALILTYDITCEESFRCLPEWLREIEQYA----SNKVITV 118
            WD AGQERF ++T+ YY+ A    + +D+T   +F  + +W  +++        + V  V
Sbjct: 1376 WDIAGQERFGNMTRVYYKEAVGAFVVFDVTRASTFDAVTKWKNDLDSKVQLADGSPVPCV 1197

Query: 119  LVGNKIDLAERREVSQ-QRAEEF-SEAQDMYYLETSAKESDNVEKLFLDLACRLISEARQ 176
            L+ NK D A+   V+   + +EF SE   + + ETSAKE+ N+++    L  R++ + R 
Sbjct: 1196 LLANKCDQAKEGLVNNTSQMDEFCSEKGFIGWYETSAKENINIDEAARFLVTRILEKDRA 1017

Query: 177  NTL------VNNVSSPLPGEGKSISYLTCC 200
              L       + +    P  G     + CC
Sbjct: 1016 MQLGDDDRDRDRIVLDKPSSGTQERKINCC 927
>17511
          Length = 483

 Score =  103 bits (256), Expect = 6e-23,   Method: Compositional matrix adjust.
 Identities = 51/122 (41%), Positives = 76/122 (62%), Gaps = 4/122 (3%)
 Frame = -3

Query: 9   LFKIVLIGNAGVGKTCLVRRFTQGLFPPGQGATIGVDFMIKTVEINGEKVKLQIWDTAGQ 68
           L K++++G++GVGKT L+ ++    F     ATIG DF+ K V ++   V +QIWDTAGQ
Sbjct: 367 LLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQIWDTAGQ 188

Query: 69  ERFRSITQSYYRSANALILTYDITCEESFRCLPEWLREIEQYASNK----VITVLVGNKI 124
           ERF+S+  ++YR A+  +L +D+T   +FR L  W  E    AS +       V++GNKI
Sbjct: 187 ERFQSLGVAFYRGADCCVLVFDVTMPNTFRSLDSWRDEFLIQASPRDPENFPFVVIGNKI 8

Query: 125 DL 126
           DL
Sbjct: 7   DL 2
>33794
          Length = 779

 Score =  100 bits (250), Expect = 3e-22,   Method: Compositional matrix adjust.
 Identities = 51/124 (41%), Positives = 80/124 (64%)
 Frame = -1

Query: 44  VDFMIKTVEINGEKVKLQIWDTAGQERFRSITQSYYRSANALILTYDITCEESFRCLPEW 103
           V +   T+ + G++VKLQIWDT+GQ RF +I +SY R A  +IL YDIT + SF  +  W
Sbjct: 692 VAYKTTTILLEGKRVKLQIWDTSGQGRFCTIIRSYSRGAQGIILVYDITNKWSFDGIDRW 513

Query: 104 LREIEQYASNKVITVLVGNKIDLAERREVSQQRAEEFSEAQDMYYLETSAKESDNVEKLF 163
           L+E+E++A   +  VLVGN++ LA +R+V+ ++AE ++   +M   E S     N+ + F
Sbjct: 512 LKEVEEHAPG-IPKVLVGNRLHLAYKRQVAAKQAETYASRNNMSCFEISPLCDFNIRESF 336

Query: 164 LDLA 167
            +LA
Sbjct: 335 CELA 324
>01972
          Length = 2359

 Score = 86.7 bits (213), Expect(2) = 6e-22,   Method: Compositional matrix adjust.
 Identities = 43/134 (32%), Positives = 76/134 (56%)
 Frame = +3

Query: 40  ATIGVDFMIKTVEINGEKVKLQIWDTAGQERFRSITQSYYRSANALILTYDITCEESFRC 99
           AT+GV+        +  K+K  +WDTAGQE+F  +   YY      ++ +D+T   +++ 
Sbjct: 393 ATLGVEVHPLLFHTSRGKLKFNVWDTAGQEKFGGLRDGYYIQGQCAVIMFDVTSRVTYKN 572

Query: 100 LPEWLREIEQYASNKVITVLVGNKIDLAERREVSQQRAEEFSEAQDMYYLETSAKESDNV 159
           +P W R++ +   N +  VL GNK+D+ +R+   + +A  F   +++ Y + SAK + N 
Sbjct: 573 VPNWHRDLVRVCEN-IPIVLCGNKVDIKDRK--VKAKAIVFHRKKNLQYYDISAKSNYNF 743

Query: 160 EKLFLDLACRLISE 173
           EK FL LA +L+ +
Sbjct: 744 EKPFLWLARKLVGD 785

 Score = 33.9 bits (76), Expect(2) = 6e-22,   Method: Compositional matrix adjust.
 Identities = 14/25 (56%), Positives = 18/25 (72%)
 Frame = +1

Query: 10  FKIVLIGNAGVGKTCLVRRFTQGLF 34
           FK+VL+G+ GVGKT  V+R   G F
Sbjct: 304 FKLVLVGDGGVGKTTFVKRHVTGEF 378
>30760
          Length = 596

 Score = 97.8 bits (242), Expect = 3e-21,   Method: Compositional matrix adjust.
 Identities = 56/162 (34%), Positives = 89/162 (54%), Gaps = 5/162 (3%)
 Frame = -1

Query: 11  KIVLIGNAGVGKT--CLVRRFTQGLFPPGQGATIGVDFMIKTVEI--NGEKVKLQIWDTA 66
           K ++ G++GVGK+  C V       FP     T GV+ ++K V I  + ++V+L ++D+A
Sbjct: 524 KCIVTGDSGVGKSSICQVFHSDSAHFPKNYSMTTGVEVLVKLVNIPDSRDQVELYLFDSA 345

Query: 67  GQERFRSITQSYYRSANALILTYDITCEESFRCLPEWLREIEQYASNKVIT-VLVGNKID 125
           G+E F      ++   + +++ YD+T E SF     WL  +     N VI  VLV NK D
Sbjct: 344 GKEIFSENVTKFWDQPSVVMVVYDVTDETSFSGCVRWLERVRAAKPNTVIPGVLVANKTD 165

Query: 126 LAERREVSQQRAEEFSEAQDMYYLETSAKESDNVEKLFLDLA 167
           L ERR VS++  ++ +++  + Y E SAKE  N +  F  LA
Sbjct: 164 LDERRRVSRKEGKDLAQSHGLEYFECSAKEMQNTDTPFFCLA 39
>33380
          Length = 282

 Score = 90.5 bits (223), Expect = 4e-19,   Method: Compositional matrix adjust.
 Identities = 43/81 (53%), Positives = 56/81 (69%)
 Frame = +3

Query: 50  TVEINGEKVKLQIWDTAGQERFRSITQSYYRSANALILTYDITCEESFRCLPEWLREIEQ 109
           TV    ++VKLQIWDTAGQER+R+IT +YYR A   IL YD+T EESF  + +W  +I+ 
Sbjct: 36  TVFRQDKRVKLQIWDTAGQERYRTITTAYYRGAMGFILMYDVTNEESFNAVQDWCTQIKT 215

Query: 110 YASNKVITVLVGNKIDLAERR 130
           Y+ +    VLVGNK DL + R
Sbjct: 216 YSWDNAQVVLVGNKCDLEDER 278
>11257
          Length = 1102

 Score = 87.4 bits (215), Expect = 4e-18,   Method: Compositional matrix adjust.
 Identities = 50/127 (39%), Positives = 75/127 (59%), Gaps = 5/127 (3%)
 Frame = -2

Query: 49   KTVEINGEKVKLQIWDTAGQERFRSITQSYYRSANALILTYDITCEESFRCLPEWLREIE 108
            K V ++GE   +QIWDTAGQER++S+   +YR  +  +LT+ +   +S + L +W  E  
Sbjct: 1053 KDVVVDGETFTMQIWDTAGQERYKSLRTPFYRGTDCCLLTFSVDNLKSLQSLSDWYDEFV 874

Query: 109  QYA----SNKVITVLVGNKIDLAERREVSQQRAEEFSEAQ-DMYYLETSAKESDNVEKLF 163
             YA    S     V++GNK D+ E REVS + A  +     ++ Y ETSAK+S NV++ F
Sbjct: 873  NYADIQDSASFPFVIIGNKADI-EEREVSSEDAYNWCRTHGNLPYFETSAKDSLNVQQAF 697

Query: 164  LDLACRL 170
            L +  RL
Sbjct: 696  LAVVRRL 676
>13901
          Length = 962

 Score = 87.0 bits (214), Expect = 4e-18,   Method: Compositional matrix adjust.
 Identities = 40/96 (41%), Positives = 63/96 (65%), Gaps = 1/96 (1%)
 Frame = -3

Query: 9   LFKIVLIGNAGVGKTCLVRRFTQGLFPPGQGATIGVDFMIKTVEINGE-KVKLQIWDTAG 67
           LFK+++IG+  VGKT  V+R+    F      TIGVDF +K +  + +  +KLQ+WD AG
Sbjct: 288 LFKVIIIGDPTVGKTSFVQRYVNDSFRRDYKMTIGVDFALKVIRWSDKCNIKLQLWDIAG 109

Query: 68  QERFRSITQSYYRSANALILTYDITCEESFRCLPEW 103
           QERF S+T+ YY+ A+A I+ +D+T + +++    W
Sbjct: 108 QERFTSMTRVYYKDAHACIVMFDLTQKNTYQNAIRW 1
>27191
          Length = 443

 Score = 85.1 bits (209), Expect = 2e-17,   Method: Compositional matrix adjust.
 Identities = 36/117 (30%), Positives = 65/117 (55%)
 Frame = +1

Query: 22  KTCLVRRFTQGLFPPGQGATIGVDFMIKTVEINGEKVKLQIWDTAGQERFRSITQSYYRS 81
           KTCL++ F +  F  G   T+GVD+  K   +NG  +++ +WD +G   +  +    Y  
Sbjct: 1   KTCLIKHFCESKFNQGYQPTVGVDYGFKIQTVNGVDMRVHMWDLSGSNEYLDVRNELYTG 180

Query: 82  ANALILTYDITCEESFRCLPEWLREIEQYASNKVITVLVGNKIDLAERREVSQQRAE 138
           ++A+ + +D++   SF  L  WLREI ++A+   + V+VGN++      +  QQ+ E
Sbjct: 181 SDAIFIVFDVSNTPSFEALDSWLREINRFATGSPLNVIVGNRVI*NRSAQCRQQKQE 351
>13750
          Length = 503

 Score = 84.7 bits (208), Expect = 2e-17,   Method: Compositional matrix adjust.
 Identities = 50/151 (33%), Positives = 76/151 (50%), Gaps = 5/151 (3%)
 Frame = -2

Query: 22  KTCLVRRFTQGLFPPGQGATIGVDFMIKTVEINGEK-----VKLQIWDTAGQERFRSITQ 76
           KTCL+RR+ +G F      TI V       E N  +     V+  +WDT G E +RS+  
Sbjct: 502 KTCLLRRYQKGFFMDRTMPTIAV----LCSEFNESRTDPLNVRYTLWDTGGAETYRSLWV 335

Query: 77  SYYRSANALILTYDITCEESFRCLPEWLREIEQYASNKVITVLVGNKIDLAERREVSQQR 136
           S++R A   +L YD+TCE SF       R+       +   + VG+K DL E R +S +R
Sbjct: 334 SHFRGAQVALLVYDVTCEWSFLTATTVWRKALMKNIPEAQVIFVGSKTDLEENRVISTER 155

Query: 137 AEEFSEAQDMYYLETSAKESDNVEKLFLDLA 167
            + F+      + ETS+    NV+ +F ++A
Sbjct: 154 GQAFATQCGYTFFETSSVTGKNVDAVFWEIA 62
>01398
          Length = 1421

 Score = 81.3 bits (199), Expect = 3e-16,   Method: Compositional matrix adjust.
 Identities = 39/101 (38%), Positives = 62/101 (61%), Gaps = 1/101 (0%)
 Frame = -2

Query: 68   QERFRSITQSYYRSANALILTYDITCEESFRCLPEWLREIEQY-ASNKVITVLVGNKIDL 126
            QERFRSIT+SYYR++  +I+ YDIT   +F  L +W  E   +   +K I +++G+K D 
Sbjct: 1420 QERFRSITRSYYRNSVGVIIVYDITKRSTFENLKQWYEEARNHIEPHKAIFLVLGHKSDR 1241

Query: 127  AERREVSQQRAEEFSEAQDMYYLETSAKESDNVEKLFLDLA 167
             + R+V+ +    F+E   + + ETSAK   N+E +F  +A
Sbjct: 1240 EDARQVTAREGRRFAEMHGLKFFETSAKSGHNIEDVFAQIA 1118
>35581
          Length = 364

 Score = 77.8 bits (190), Expect = 3e-15,   Method: Compositional matrix adjust.
 Identities = 39/95 (41%), Positives = 57/95 (60%), Gaps = 1/95 (1%)
 Frame = +2

Query: 10  FKIVLIGNAGVGKTCLVRRFTQGLFPPGQGATIGVDFMIKTVEI-NGEKVKLQIWDTAGQ 68
           FK VL+G+AGVGKTCL+ R     F      ++    ++ TV + +G    + +WDTAGQ
Sbjct: 47  FKCVLLGDAGVGKTCLLNRLATDKFLDSPLTSLTTASLLTTVTLTSGVMASVDLWDTAGQ 226

Query: 69  ERFRSITQSYYRSANALILTYDITCEESFRCLPEW 103
           ER+RS+T SYYR   A+++ YD   E   + L +W
Sbjct: 227 ERYRSLTSSYYRDTKAVLIVYD--AEHKLK-LTDW 322
>19006
          Length = 568

 Score = 77.4 bits (189), Expect = 4e-15,   Method: Compositional matrix adjust.
 Identities = 41/133 (30%), Positives = 75/133 (56%), Gaps = 5/133 (3%)
 Frame = -2

Query: 11  KIVLIGNAGVGKTCLVRRFTQGLFPPGQGATIGVDFMIKTVEINGEKVKLQIWDTAGQER 70
           K+V++G+   GKTCL+  F++  FP     T+  ++ +  +E++ ++V+L +WDTAGQE 
Sbjct: 432 KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENY-VADIEVDSKQVELALWDTAGQED 256

Query: 71  FRSITQSYYRSANALILTYDITCEESFRCLPE-WLREIEQYASNKVITVLVGNKIDLAE- 128
           +  +    Y   + +++ + I   +S   +PE W  E+  +  N V  +LVGNK DL   
Sbjct: 255 YDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVRHFCPN-VPIILVGNKKDLRND 79

Query: 129 ---RREVSQQRAE 138
              +RE+ + + E
Sbjct: 78  ENTKRELMKMKQE 40
>07580
          Length = 921

 Score = 77.4 bits (189), Expect = 4e-15,   Method: Compositional matrix adjust.
 Identities = 47/138 (34%), Positives = 77/138 (55%), Gaps = 1/138 (0%)
 Frame = +3

Query: 31  QGLFPPGQGATIGVDFMIKTVEINGEKVKLQIWDTAGQERFRSITQSYYRSANALILTYD 90
           +G+F      TI  D   K VE++G++  L+I DTAG E+F ++   Y ++    +L Y 
Sbjct: 126 KGIFVEKYDPTIE-DSYRKQVEVDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFLLAYS 302

Query: 91  ITCEESFRCLPEWLREIEQYA-SNKVITVLVGNKIDLAERREVSQQRAEEFSEAQDMYYL 149
           IT + +F  L E   +I +   ++ V  +LVGNK DL + R V + + +  + +    +L
Sbjct: 303 ITAQSTFNDLQELREQILRVKDTDDVPMLLVGNKCDLEDERVVGKDQGQGLARSFSCAFL 482

Query: 150 ETSAKESDNVEKLFLDLA 167
           ETSAK   NV ++F+DL 
Sbjct: 483 ETSAKARINVNEIFMDLV 536
>13745
          Length = 1045

 Score = 74.7 bits (182), Expect = 3e-14,   Method: Compositional matrix adjust.
 Identities = 45/120 (37%), Positives = 73/120 (60%), Gaps = 5/120 (4%)
 Frame = +2

Query: 68  QERFRSITQSYYRSANALILTYDITCEESFRCLPEWLREIEQYASNK----VITVLVGNK 123
           QERF+S+  ++YR A+  +L YD+T   SF+ L  W  E    AS +       V++GNK
Sbjct: 2   QERFQSLGVAFYRGADCCVLVYDVTAPNSFKNLDSWRDEFLIQASPRDPEHFPFVVLGNK 181

Query: 124 IDLAERREVSQQRAEEFSEAQ-DMYYLETSAKESDNVEKLFLDLACRLISEARQNTLVNN 182
           +DL + R+VS +RA+++ +++ D+ Y ETSAKE  NVE  F  +A   + +  +  L+N+
Sbjct: 182 VDL-DNRQVSTRRAQQWCQSKNDIPYYETSAKEGINVEMAFQTIAKNALEQETEAELIND 358
>11728
          Length = 635

 Score = 72.0 bits (175), Expect = 1e-13,   Method: Compositional matrix adjust.
 Identities = 39/131 (29%), Positives = 67/131 (51%), Gaps = 1/131 (0%)
 Frame = -1

Query: 10  FKIVLIGNAGVGKTCLVRRFTQGLFPPGQGATIGVDFMIKTVEINGEKVKLQIWDTAGQE 69
            K V++G+  VGKTCL+  +T   FP G+      D     V ++ + + L +WDTAGQE
Sbjct: 488 IKCVVVGDGAVGKTCLLISYTTNAFP-GEYIPTVFDNYSANVMVDSKPINLGLWDTAGQE 312

Query: 70  RFRSITQSYYRSANALILTYDITCEESFRCL-PEWLREIEQYASNKVITVLVGNKIDLAE 128
            +  +    Y   +  ++ + +    SF  +  +W  E+  +  N  I +LVG K+DL E
Sbjct: 311 DYDRLRPLSYPQTDVFLICFSLISPASFENVKAKWYPEVSHHCPNTPI-ILVGTKLDLRE 135

Query: 129 RREVSQQRAEE 139
            +E  ++  E+
Sbjct: 134 DKETIEKLKEK 102
>26536
          Length = 829

 Score = 69.7 bits (169), Expect = 7e-13,   Method: Compositional matrix adjust.
 Identities = 48/140 (34%), Positives = 68/140 (48%), Gaps = 3/140 (2%)
 Frame = +2

Query: 57  KVKLQIWDTAGQERFRSITQSYYRSANALILTYDITCEESFR---CLPEWLREIEQYASN 113
           +V     DTAGQE + S+ + Y RS +  I+ Y +T   SF+    +  WL   +   S 
Sbjct: 125 RVSWTFLDTAGQEEYSSMREHYTRSGDGFIVVYSVTDVTSFQEAEAVFRWLTRFQDETS- 301

Query: 114 KVITVLVGNKIDLAERREVSQQRAEEFSEAQDMYYLETSAKESDNVEKLFLDLACRLISE 173
            +  VL GNK DL   R+V+ +   + ++   M Y ETSAK  DNV +++  L   L S 
Sbjct: 302 -IHAVLCGNKTDLTSDRKVTPEEGRKMADRLGMLYFETSAKTGDNVSQVYHGL---LRSI 469

Query: 174 ARQNTLVNNVSSPLPGEGKS 193
            R  T    V     G GKS
Sbjct: 470 PRSGTDYKIVMLGSGGVGKS 529

 Score = 35.4 bits (80), Expect = 0.014,   Method: Compositional matrix adjust.
 Identities = 19/47 (40%), Positives = 29/47 (61%)
 Frame = +2

Query: 10  FKIVLIGNAGVGKTCLVRRFTQGLFPPGQGATIGVDFMIKTVEINGE 56
           +KIV++G+ GVGK+ L  RFTQ  F      TI  D   K ++++G+
Sbjct: 488 YKIVMLGSGGVGKSSLTIRFTQDTFLDVYDPTI-EDSYRKMIQVSGQ 625
>01095
          Length = 1745

 Score = 68.9 bits (167), Expect = 1e-12,   Method: Compositional matrix adjust.
 Identities = 31/84 (36%), Positives = 54/84 (64%)
 Frame = -1

Query: 87   LTYDITCEESFRCLPEWLREIEQYASNKVITVLVGNKIDLAERREVSQQRAEEFSEAQDM 146
            + YDIT +++F     W++E+++ AS  ++  L GNK DLA +R V  + A+ ++E   +
Sbjct: 1745 VVYDITNQDTFGRAKTWVKELQRQASPNIVIALAGNKADLANKRMVEFEEAQAYAEENSL 1566

Query: 147  YYLETSAKESDNVEKLFLDLACRL 170
             ++ETSAK + NV  +FL +A +L
Sbjct: 1565 LFMETSAKTAMNVNDIFLAIAKKL 1494
>12339
          Length = 578

 Score = 68.2 bits (165), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 43/111 (38%), Positives = 66/111 (59%), Gaps = 5/111 (4%)
 Frame = -2

Query: 68  QERFRSITQSYYRSANALILTYDITCEESFRCLPEWLREIEQYASNK----VITVLVGNK 123
           QERF+S+  ++YR A+  IL YD+T  ++F  L  W RE    AS +       V++GNK
Sbjct: 577 QERFQSLGVAFYRGADCCILVYDVTEXKTFDSLDSWQREFLNQASPRDPEHFPFVVIGNK 398

Query: 124 IDLAERREVSQQRAEEF-SEAQDMYYLETSAKESDNVEKLFLDLACRLISE 173
           IDL + R V+ +R + + S    + Y ETSAKE+ NVE+ F  +A   +++
Sbjct: 397 IDL-DNRVVTAKRGQGWCSTKGGIPYFETSAKEAINVEQAFQTVAKNALAQ 248
>34359
          Length = 1042

 Score = 66.6 bits (161), Expect = 7e-12,   Method: Compositional matrix adjust.
 Identities = 38/123 (30%), Positives = 67/123 (54%), Gaps = 2/123 (1%)
 Frame = +3

Query: 10  FKIVLIGNAGVGKTCLVRRFTQGLFPPGQGATIGVDFMIKTVEINGEK--VKLQIWDTAG 67
           FK+VL+G        +V+R   G       AT+GV+  +  ++ N  +  ++  +WDTAG
Sbjct: 54  FKLVLVGGRWEWANNIVKRHVTG-S*KKYVATLGVE--VHPLQFNTSRGLLRFNVWDTAG 224

Query: 68  QERFRSITQSYYRSANALILTYDITCEESFRCLPEWLREIEQYASNKVITVLVGNKIDLA 127
           QE+F  +   YY      I+ +D+T   +++ +P W R++ +   N  I VL GNK+D+ 
Sbjct: 225 QEKFGGLRDGYYIQGTCAIIMFDVTSRVTYKNVPNWHRDLVRVCENIPI-VLCGNKVDIK 401

Query: 128 ERR 130
           +R+
Sbjct: 402 DRK 410
>34597
          Length = 773

 Score = 64.3 bits (155), Expect = 3e-11,   Method: Compositional matrix adjust.
 Identities = 37/127 (29%), Positives = 70/127 (55%), Gaps = 3/127 (2%)
 Frame = -2

Query: 77  SYYRSANALILTYDITCEESFRCLPEWLREIEQYASNKVITVLVGNKIDLAERREVSQQR 136
           S+    NA ++T  +  ++SF  + +WLR I+++A+  V  +++GNK D+ ++R VS++R
Sbjct: 760 SWSDGHNACLMT*RM--KKSFENIVKWLRNIDEHANEDVEKMILGNKCDMTDKRVVSKER 587

Query: 137 AEEFSEAQDMYYLETSAKESDNVEKLFLDLACRLISEARQNTLVNNVSSPLPGEG---KS 193
            E  +    + ++ETSAK + N+E+ F +LA  ++ +        N    +   G   K+
Sbjct: 586 GEAIAREHSIRFMETSAKSNINIERAFCELAEAILDKTAGRESAENPERVVIDRGNSDKA 407

Query: 194 ISYLTCC 200
             Y  CC
Sbjct: 406 PGYNKCC 386
>29380
          Length = 853

 Score = 63.5 bits (153), Expect = 5e-11,   Method: Compositional matrix adjust.
 Identities = 32/93 (34%), Positives = 55/93 (59%), Gaps = 1/93 (1%)
 Frame = -2

Query: 82  ANALILTYDITCEESFRCLPEWLREIEQYASNKVITVLVGNKIDLA-ERREVSQQRAEEF 140
           A+A I+ YD+   ++F     W++E+ Q  +  V+ +L GNK+DLA + R VS + A+ F
Sbjct: 852 ASAAIIVYDVNIADTFSRALAWVKELRQQNTESVLIILAGNKVDLATQHRAVSFEDAQSF 673

Query: 141 SEAQDMYYLETSAKESDNVEKLFLDLACRLISE 173
           +    + + E SAK    V ++F+ LA +LI +
Sbjct: 672 ARENGLLFAEVSAKTGMAVNEIFMTLANQLIQQ 574
>19656
          Length = 428

 Score = 60.5 bits (145), Expect = 5e-10,   Method: Compositional matrix adjust.
 Identities = 31/101 (30%), Positives = 50/101 (49%), Gaps = 1/101 (0%)
 Frame = +3

Query: 11  KIVLIGNAGVGKTCLVRRFTQGLFPPGQGATIGVDFMIKTVEINGEKVKLQIWDTAGQER 70
           K V++G+  VGKTCL+  +T   FP G+      D     V ++G  V L +WDTAGQE 
Sbjct: 117 KCVVVGDGAVGKTCLLISYTTNAFP-GEYIPTVFDNYSANVMVDGRPVNLGLWDTAGQED 293

Query: 71  FRSITQSYYRSANALILTYDITCEESFRCL-PEWLREIEQY 110
           +  +    Y   +  +L + +    SF  +  +W  E+  +
Sbjct: 294 YDRLRPLSYPQTDVFLLCFSVASPASFENIRAKWYPEVNHH 416
>00858
          Length = 1658

 Score = 58.5 bits (140), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 39/119 (32%), Positives = 64/119 (53%), Gaps = 1/119 (0%)
 Frame = -2

Query: 49   KTVEINGEKVKLQIWDTAGQERFRSITQSYYRSANALILTYDITCEESFRCLPEWLREIE 108
            K V I+GE   L I DTAGQE   ++     R+    +  + +   +SF  + ++  +I+
Sbjct: 1474 KQVVIDGETCLLDILDTAGQEEXSAMRDQCMRTGEGFLCVFAVXNLKSFEDINQYREQIK 1295

Query: 109  QYA-SNKVITVLVGNKIDLAERREVSQQRAEEFSEAQDMYYLETSAKESDNVEKLFLDL 166
            +   +++V  VLVGNK+DL   R V Q++ +  +E   + Y+ETSAK    V+  F  L
Sbjct: 1294 RVKDADEVPMVLVGNKVDLP-IRNVEQRQGKHMAELYHIPYVETSAKTRQGVDDAFYTL 1121
>14775
          Length = 380

 Score = 56.6 bits (135), Expect = 7e-09,   Method: Compositional matrix adjust.
 Identities = 30/78 (38%), Positives = 42/78 (53%), Gaps = 5/78 (6%)
 Frame = -2

Query: 22  KTCLVRRFTQGLFPPGQGATIGVDFMIKTVEINGEK-----VKLQIWDTAGQERFRSITQ 76
           KTCL+RR+ +G F      TI V       E N  +     V+  +WDT G E +RS+  
Sbjct: 379 KTCLLRRYQKGFFMDRTMPTIAV----LCSEFNESRTDPLNVRYTLWDTGGAETYRSLWV 212

Query: 77  SYYRSANALILTYDITCE 94
           S++R A   +L YD+TCE
Sbjct: 211 SHFRGAQVALLVYDVTCE 158
>09204
          Length = 1051

 Score = 53.1 bits (126), Expect = 7e-08,   Method: Compositional matrix adjust.
 Identities = 34/102 (33%), Positives = 55/102 (53%), Gaps = 4/102 (3%)
 Frame = -3

Query: 70   RFRSITQSYYRSANALILTYDITCEESFRCLPEWLREIEQYASNKVITVLVGNKIDLA-- 127
            R+ ++++ YYR A A IL +D+T + SF  +  W+ E+ Q+   +    + G K DL   
Sbjct: 1049 RYEAMSRIYYRGAKAAILCFDLTDKSSFDRIRFWIGELRQH-EEECKLYICGTKFDLVHD 873

Query: 128  --ERREVSQQRAEEFSEAQDMYYLETSAKESDNVEKLFLDLA 167
              ERR V +  A+  ++       ETS+   DN+EKLF  +A
Sbjct: 872  DPERRAVPRSVAKALADDCMAEIYETSSMTGDNIEKLFTKIA 747
>14119
          Length = 602

 Score = 53.1 bits (126), Expect = 8e-08,   Method: Compositional matrix adjust.
 Identities = 30/80 (37%), Positives = 45/80 (56%), Gaps = 1/80 (1%)
 Frame = +1

Query: 98  RCLPEWLREIEQYASNKVITVLVGNKIDLA-ERREVSQQRAEEFSEAQDMYYLETSAKES 156
           R L  W++E+ Q  +  V+ VL GNK DLA E R VS   A  F+E   + + E SAK  
Sbjct: 10  RALA-WVKELRQQNAGSVLIVLAGNKADLASEHRAVSADDARTFAEDNGLIFAEVSAKTG 186

Query: 157 DNVEKLFLDLACRLISEARQ 176
             V ++F+ +A +L+  A +
Sbjct: 187 MAVSEVFMTIAHKLVRRAEE 246
>31291
          Length = 446

 Score = 50.1 bits (118), Expect = 6e-07,   Method: Compositional matrix adjust.
 Identities = 34/118 (28%), Positives = 59/118 (50%), Gaps = 14/118 (11%)
 Frame = -1

Query: 60  LQIWDTAGQERFRSITQSYYRSANALILTYDITCEESFRCLP-EWLREIEQYASNKVITV 118
           LQ+WDTAGQE +  +    Y + +  +L + +  E S + +  +W  EI  +  + V  V
Sbjct: 446 LQLWDTAGQEDYDRLRPLAYPNTDVFMLXFSLMSEASMKNVKVKWYPEIRHHDPH-VPIV 270

Query: 119 LVGNKIDLAERRE------------VSQQRAEEFSEA-QDMYYLETSAKESDNVEKLF 163
           LVG K+DL + +E            VS  +  + ++A +   Y E S+K  +N++  F
Sbjct: 269 LVGTKLDLRQDKEAVRKLRSSRQDPVSSNQGNDLAKAIKAKRYFECSSKTQENLKTAF 96
>10708
          Length = 2775

 Score = 37.0 bits (84), Expect(2) = 7e-07,   Method: Compositional matrix adjust.
 Identities = 14/47 (29%), Positives = 27/47 (57%)
 Frame = -2

Query: 56   EKVKLQIWDTAGQERFRSITQSYYRSANALILTYDITCEESFRCLPE 102
            ++V+L +WDTAGQE +  +    Y   + +++ + I   +S   +PE
Sbjct: 2729 QQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPE 2589

 Score = 32.3 bits (72), Expect(2) = 7e-07,   Method: Compositional matrix adjust.
 Identities = 26/77 (33%), Positives = 38/77 (49%), Gaps = 13/77 (16%)
 Frame = -3

Query: 100  LPEWLREIEQYASNKVITVLVGNKIDLAE----RREVSQQRAEE--------FSEAQDMY 147
            L +W  E+  +  N V  +LVGNK DL      +RE+ + + E          SE  + Y
Sbjct: 2593 LKKWTPEVRHFCPN-VPIILVGNKKDLRNDENTKRELMKMKQEPVRLDEGRAMSEKINAY 2417

Query: 148  -YLETSAKESDNVEKLF 163
             YLE SAK  + V ++F
Sbjct: 2416 SYLECSAKTKEGVREVF 2366
>00552
          Length = 455

 Score = 48.5 bits (114), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 23/53 (43%), Positives = 33/53 (62%)
 Frame = -1

Query: 9   LFKIVLIGNAGVGKTCLVRRFTQGLFPPGQGATIGVDFMIKTVEINGEKVKLQ 61
           L K+VL+G+ GVGK+ L+ RF    F      TIGV+F+ K V ++GE   +Q
Sbjct: 446 LLKVVLLGDGGVGKSSLMNRFVSNKFDAQSFHTIGVEFLTKDVVVDGETFTMQ 288

 Score = 46.2 bits (108), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 19/49 (38%), Positives = 30/49 (61%)
 Frame = -3

Query: 62  IWDTAGQERFRSITQSYYRSANALILTYDITCEESFRCLPEWLREIEQY 110
           IWDTAGQER++S+   +YR  +  +LT+ +   +S + L +W  E   Y
Sbjct: 147 IWDTAGQERYKSLRTPFYRGTDCCLLTFSVDNLKSLQSLSDWYDEFVNY 1
>25618
          Length = 475

 Score = 47.8 bits (112), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 27/73 (36%), Positives = 41/73 (56%), Gaps = 1/73 (1%)
 Frame = +3

Query: 105 REIEQYASNKVITVLVGNKIDLA-ERREVSQQRAEEFSEAQDMYYLETSAKESDNVEKLF 163
           +E+ Q  +  V+ VL GNK DLA E R VS   A  F+E   + + E SAK    V ++F
Sbjct: 48  KELRQQNAGSVLIVLAGNKADLASEHRAVSADDARTFAEDNGLIFAEVSAKTGMAVSEVF 227

Query: 164 LDLACRLISEARQ 176
           + +A +L+  A +
Sbjct: 228 MTIAHKLVRRAEE 266
>19046
          Length = 445

 Score = 45.8 bits (107), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 28/101 (27%), Positives = 53/101 (52%), Gaps = 1/101 (0%)
 Frame = -2

Query: 68  QERFRSITQSYYRSANALILTYDITCEESFRCLPEWLREIEQYAS-NKVITVLVGNKIDL 126
           QE F ++ + Y R  +  +L + +T   SF  +  +  +I +    +    +L  NK+DL
Sbjct: 444 QEEFSAMREQYMRKGDGFLLVFSVTDFRSFENMANFHTQILRVKDRDSYPMILCANKVDL 265

Query: 127 AERREVSQQRAEEFSEAQDMYYLETSAKESDNVEKLFLDLA 167
             +R+VS+++  + +    + Y+ETSAK+      L +DLA
Sbjct: 264 VHQRKVSEEQVRDLATRLRIPYIETSAKDP----PLNVDLA 154
>24619
          Length = 509

 Score = 44.3 bits (103), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 27/101 (26%), Positives = 52/101 (51%), Gaps = 1/101 (0%)
 Frame = -2

Query: 68  QERFRSITQSYYRSANALILTYDITCEESFRCLPEWLREIEQYASNKVIT-VLVGNKIDL 126
           QE F ++ + Y R  +  +L + +   +SF  +  +  +I +         +L  NK+DL
Sbjct: 508 QEEFSAMREQYMRKGDGFLLVFSVIDYQSFENMVNFHTQILRVKDRDTYPMILCANKVDL 329

Query: 127 AERREVSQQRAEEFSEAQDMYYLETSAKESDNVEKLFLDLA 167
             +R+VS+++  + +    + Y+ETSAK+      L +DLA
Sbjct: 328 VHQRKVSEEQVRDLATRLRIPYIETSAKDP----PLNVDLA 218
>33605
          Length = 888

 Score = 44.3 bits (103), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 26/80 (32%), Positives = 44/80 (55%)
 Frame = +1

Query: 11  KIVLIGNAGVGKTCLVRRFTQGLFPPGQGATIGVDFMIKTVEINGEKVKLQIWDTAGQER 70
           +++++G    GKT ++++F  G        T+G  F IKT+E  G   KL +WD  GQ+ 
Sbjct: 502 RLLMLGLDNAGKTTILKKF-NGEDIDTISPTLG--FNIKTLEHRG--FKLNVWDVGGQQS 666

Query: 71  FRSITQSYYRSANALILTYD 90
            RS  ++Y+ S + L+   D
Sbjct: 667 LRSYWRNYFESTDGLVWVVD 726
>08153
          Length = 1703

 Score = 41.6 bits (96), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 33/129 (25%), Positives = 57/129 (44%), Gaps = 1/129 (0%)
 Frame = +1

Query: 11  KIVLIGNAGVGKTCLVRRFTQGLFPPGQGATIGVDFMIKTVEINGEKVKLQIWDTAGQER 70
           +I+++G    GKT ++ +   G        TIG  F ++TVE   + +   +WD  GQ++
Sbjct: 88  RILMVGLDAAGKTTILYKLKLGEIVTTI-PTIG--FNVETVEY--KNISFTVWDVGGQDK 252

Query: 71  FRSITQSYYRSANALILTYDITCEESFRCLPEWL-REIEQYASNKVITVLVGNKIDLAER 129
            R + + Y+++   LI   D    E      E L R + +      I ++  NK DL   
Sbjct: 253 IRPLWRHYFQNTQGLIFVVDSNDRERINEAKEELARMLNEDDLRDAIILVFANKQDLPNA 432

Query: 130 REVSQQRAE 138
              S+  A 
Sbjct: 433 YSASEVTAH 459
>25796
          Length = 422

 Score = 41.2 bits (95), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 15/26 (57%), Positives = 21/26 (80%)
 Frame = -1

Query: 4  EDYDFLFKIVLIGNAGVGKTCLVRRF 29
          E YD+LFK ++IG+AG GK+CL+  F
Sbjct: 83 ETYDYLFKFLIIGSAGSGKSCLLHHF 6
>09827
          Length = 1201

 Score = 40.4 bits (93), Expect = 6e-04,   Method: Compositional matrix adjust.
 Identities = 30/124 (24%), Positives = 56/124 (45%), Gaps = 5/124 (4%)
 Frame = -3

Query: 10   FKIVLIGNAGVGKTCLVRRFTQG----LFPPGQGATIGVDFMIKTVEINGEKVKLQIWDT 65
             +I+++G    GKT ++ +   G      P     TIG  F ++TVE   + +   +WD 
Sbjct: 1112 MRILMVGLDAAGKTTILYKLKLGEIVTTIP-----TIG--FNVETVEY--KNISFTVWDV 960

Query: 66   AGQERFRSITQSYYRSANALILTYDITCEESFR-CLPEWLREIEQYASNKVITVLVGNKI 124
             GQ++ R + + Y+++   LI   D   +E  +    E  R + +      + ++  NK 
Sbjct: 959  GGQDKIRPLWRHYFQNTQGLIFVVDSNDKERVQEAREELTRMLNEDELRDAVLLVFANKQ 780

Query: 125  DLAE 128
            DL  
Sbjct: 779  DLPH 768
>18509
          Length = 625

 Score = 39.3 bits (90), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 22/55 (40%), Positives = 33/55 (60%)
 Frame = -3

Query: 112 SNKVITVLVGNKIDLAERREVSQQRAEEFSEAQDMYYLETSAKESDNVEKLFLDL 166
           +++V  VLVGNK+DL   R V Q++ +  +E   + Y+ETSAK    V+  F  L
Sbjct: 536 ADEVPMVLVGNKVDLP-IRNVEQRQGKHMAELYHIPYVETSAKTRQGVDDAFYTL 375
>31928
          Length = 429

 Score = 35.8 bits (81), Expect = 0.012,   Method: Compositional matrix adjust.
 Identities = 21/73 (28%), Positives = 39/73 (53%), Gaps = 4/73 (5%)
 Frame = +2

Query: 55  GEKVKLQIWDTAG---QERFRSITQSYYRSANALILTYDITCEESFRCLPEWLREIEQYA 111
           G K K++I+DT     +     + + Y    +  +L YD T  ESFR L +  ++I+++ 
Sbjct: 95  GVKEKVRIFDTGAAALETTEGDLPKHYLNFPDGFVLVYDTTSWESFRRLDKLKKDIDKHR 274

Query: 112 SNK-VITVLVGNK 123
             + V  +++GNK
Sbjct: 275 DKREVHMIVIGNK 313
>10862
          Length = 2896

 Score = 33.5 bits (75), Expect = 0.056,   Method: Compositional matrix adjust.
 Identities = 19/77 (24%), Positives = 38/77 (49%), Gaps = 4/77 (5%)
 Frame = -3

Query: 56   EKVKLQIWDTAGQERFRSITQSYYRSANALILTYDITCEESFRCLPEWLREIEQYASNK- 114
            ++ +  +WD  GQ++ R + + YY     LI   D  C +  R + E  +E+ +  +++ 
Sbjct: 2492 QECQFNVWDVGGQDKIRPLWRHYYTGTQGLIFVVD--CADRDR-IDEARQELHRIINDRE 2322

Query: 115  ---VITVLVGNKIDLAE 128
                I ++  NK DL +
Sbjct: 2321 MRDAIILIFANKQDLPD 2271
>12443
          Length = 837

 Score = 33.1 bits (74), Expect = 0.070,   Method: Compositional matrix adjust.
 Identities = 28/137 (20%), Positives = 61/137 (44%), Gaps = 9/137 (6%)
 Frame = -3

Query: 10  FKIVLIGNAGVGKTCLVRRFTQGLFPPGQGATIGVD----FMIKTVEINGEKV--KLQIW 63
           +K++L+G  GVGKT  V + T    P     T G+     +    ++  G+ V  ++Q++
Sbjct: 580 YKVMLVGKTGVGKTSTVAKLTGNDIPLTHNETPGLQTSHLYWPGKIKHLGKTVLFQIQLF 401

Query: 64  DTAGQ---ERFRSITQSYYRSANALILTYDITCEESFRCLPEWLREIEQYASNKVITVLV 120
           D AG+   +R+  I  +     + ++  +    + SF  +P+ L        + +  + +
Sbjct: 400 D-AGETALKRYDHILPACQDGVDGIMFLFSFVDKGSFDEIPQLLTRFTTL-EDGICKIAL 227

Query: 121 GNKIDLAERREVSQQRA 137
           G K     +  +++ R 
Sbjct: 226 GTKYPFPHKGIINKDRG 176
>06994
          Length = 429

 Score = 32.0 bits (71), Expect = 0.16,   Method: Compositional matrix adjust.
 Identities = 12/25 (48%), Positives = 20/25 (80%)
 Frame = +3

Query: 10 FKIVLIGNAGVGKTCLVRRFTQGLF 34
          +K+V++G+ GVGK+ L  +F QG+F
Sbjct: 57 YKLVVLGSGGVGKSALTVQFVQGIF 131
>06169
          Length = 1084

 Score = 30.0 bits (66), Expect = 0.62,   Method: Compositional matrix adjust.
 Identities = 13/37 (35%), Positives = 20/37 (54%)
 Frame = -1

Query: 11  KIVLIGNAGVGKTCLVRRFTQGLFPPGQGATIGVDFM 47
           K+ + G AGVG   L + F +G  P    A  G+D++
Sbjct: 637 KVFMFGAAGVGTVALHKIFLKGANPALDFAMAGLDYL 527
>31932
          Length = 437

 Score = 28.9 bits (63), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 18/60 (30%), Positives = 30/60 (50%), Gaps = 1/60 (1%)
 Frame = -1

Query: 103 WLREIEQYASNKVITVLVGNKIDLAERREVSQQRAEEFSEAQD-MYYLETSAKESDNVEK 161
           W   +     + V  +L+GNK DL   REV Q   E+  +  D + + ETS K+   +++
Sbjct: 437 WTASVNWPYGSTVPCLLLGNKSDLG-HREVEQDEIEDLCKEHDFLGWSETSVKDGTMIDE 261
>00235
          Length = 1186

 Score = 26.6 bits (57), Expect = 7.6,   Method: Compositional matrix adjust.
 Identities = 20/59 (33%), Positives = 33/59 (55%)
 Frame = +1

Query: 102 EWLREIEQYASNKVITVLVGNKIDLAERREVSQQRAEEFSEAQDMYYLETSAKESDNVE 160
           EW+ E+EQ+ S+K     + +   LA +R  +Q R EE S+ +     E S  ESD+++
Sbjct: 283 EWIAEMEQFTSDKRTGRSISHST-LALKRHYNQLR-EELSKLKPP--PELSDSESDSID 447
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31981382|ref|NP_035960.2| inosine 5'-phosphate
dehydrogenase 2 [Mus musculus]
         (514 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

29232                                                                 132   7e-40
09128                                                                  64   2e-10
34775                                                                  29   3.6  
>29232
          Length = 368

 Score =  132 bits (333), Expect(2) = 7e-40,   Method: Compositional matrix adjust.
 Identities = 60/97 (61%), Positives = 78/97 (80%)
 Frame = +1

Query: 110 YEQGFITDPVVLSPKDRVRDVFEAKARHGFCGIPITDTGRMGSRLVGIISSRDIDFLKEE 169
           YEQGFI DPVV+SP  RV DV EAK R GF GIP+T++G MG +LVG+++ RD+DFL ++
Sbjct: 1   YEQGFILDPVVMSPMHRVADVMEAKKRFGFSGIPVTESGHMGEKLVGLVTQRDVDFLTQD 180

Query: 170 EHDRFLEEIMTKREDLVVAPAGVTLKEANEILQRSKK 206
           +++  L E+MT+ EDL+VA  GVTLKEAN ILQ+SKK
Sbjct: 181 QYNTPLSEVMTRFEDLIVATHGVTLKEANTILQKSKK 291

 Score = 49.7 bits (117), Expect(2) = 7e-40,   Method: Composition-based stats.
 Identities = 23/30 (76%), Positives = 27/30 (90%)
 Frame = +2

Query: 202 QRSKKGKLPIVNENDELVAIIARTDLKKNR 231
           +++KKGKLPIVNE  ELVA+IARTD KKNR
Sbjct: 278 RKAKKGKLPIVNEQGELVALIARTDTKKNR 367
>09128
          Length = 1107

 Score = 63.5 bits (153), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 32/80 (40%), Positives = 49/80 (61%)
 Frame = +2

Query: 317 GVDALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVPVIADGGIQNVGHIAKA 376
           G D ++VG+G GS+C T++    G PQ +AV + ++ A   G  +I+DGG    G ++KA
Sbjct: 2   GADIIKVGIGPGSVCTTRKKTGVGYPQLSAVLECADAAHGLGGHIISDGGCTCPGDVSKA 181

Query: 377 LALGASTVMMGSLLAATTEA 396
              GA  VM+G +LA  TE+
Sbjct: 182 FGAGADFVMLGGMLAGHTES 241
>34775
          Length = 399

 Score = 29.3 bits (64), Expect = 3.6,   Method: Composition-based stats.
 Identities = 12/33 (36%), Positives = 21/33 (63%)
 Frame = -1

Query: 453 IHKFVPYLIAGIQHSCQDIGAKSLTQVRAMMYS 485
           +H + P+L+ G  HSC  +GA +   VR+++ S
Sbjct: 321 VHYWEPWLVCGSGHSCALLGALASVWVRSLVCS 223
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|40254361|ref|NP_035150.3| heat shock protein 4 like
[Mus musculus]
         (838 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

21024                                                                 107   7e-40
18301                                                                 134   2e-31
37715                                                                  75   1e-20
27378                                                                  99   1e-20
20979                                                                  91   2e-18
03996                                                                  84   3e-16
12271                                                                  76   5e-14
13300                                                                  73   5e-13
19659                                                                  65   1e-10
09881                                                                  60   4e-09
30255                                                                  58   2e-08
20381                                                                  55   1e-07
31218                                                                  51   2e-06
12634                                                                  30   5.7  
>21024
          Length = 3220

 Score =  107 bits (267), Expect(2) = 7e-40,   Method: Compositional matrix adjust.
 Identities = 77/273 (28%), Positives = 135/273 (49%), Gaps = 3/273 (1%)
 Frame = +3

Query: 3   VVGIDLGFLNCYIAVARSGGIETIANEYSDRCTPACISLGSRTRAI-GNAAKSQIVTNVR 61
           V+GIDLG  N  +A+      + + N    R TP+ I+       I G  AK Q VTN  
Sbjct: 252 VIGIDLGTTNSCVALMEGKQAKVLENSEGSRTTPSVIAFTKDGERISGMPAKRQAVTNAE 431

Query: 62  NTIHGFKKLHGRSFDDPIVQTERIRLPYELQKMPNGSTGVKVRYLEEERPFAIEQVTGML 121
           NT+   K+L GR F+DP VQ +   + Y++ K  NG   V+     + + ++  QV   +
Sbjct: 432 NTLSATKRLIGRRFEDPEVQKDMKNVSYKIVKASNGDAWVEA----QGKMYSPSQVGAFV 599

Query: 122 LAKLKETSENALKKPVADCVISIPSFFTDAERRSVMAAAQVAGLNCLRLMNETTAVALAY 181
           L K+KET+E+ L   V + V+++P++F D++R++   A Q++GL C+     T + +  +
Sbjct: 600 LMKMKETAESYLGSKVNNAVVTVPAYFNDSQRQATKDAGQISGLKCVACDQRTHSCSSCF 779

Query: 182 GIYKQDLPSLDEKPRNVVFIDMGHSAYQVSVCAFNKGK--LKVLATTFDPYLGGRNFDEA 239
             +     SL  K    +    G    +++  ++   +  LK    T       R FD  
Sbjct: 780 MAW----TSLKIK**RCLI*AEG----RLTSLSWRSRRECLKSNQPTETHSWEERTFDNY 935

Query: 240 LVDYFCDEFKTKYKINVKENSRALLRLYQECEK 272
           +V++   EFK +  +++ ++  A+ RL +  EK
Sbjct: 936 MVNFLASEFKKEQGLDITKDPMAVQRLREAAEK 1034

 Score = 75.9 bits (185), Expect(2) = 7e-40,   Method: Compositional matrix adjust.
 Identities = 53/198 (26%), Positives = 97/198 (48%), Gaps = 3/198 (1%)
 Frame = +1

Query: 300  KMNRAQFEQLCASLLARVEPPLKSVMDQANLQREDINSIEIVGGATRIPAVKEQVTRFFL 359
            K++R++FE L  SL+ R   P +  +  A +++ DI  + +VGG +R+P V+  V   F 
Sbjct: 1123 KLSRSKFESLVESLVKRTVGPCQKALQDAEVKKSDIGEVILVGGMSRMPKVQSTVQDLFG 1302

Query: 360  KDISTTLNADEAVARGCALQCAILSPAFKVREFSITDLVPYSVTLRWKTSFEEGTGECEV 419
            +  S ++N DEAVA G A+Q  +L  A  V +  + D+ P S+ +        G    ++
Sbjct: 1303 RTPSKSVNPDEAVAIGAAIQGGVL--AGDVTDVLLLDVTPLSLGIETL-----GGVFTKL 1461

Query: 420  FSKNHPAPFSKVITFHKKEPFELEA---FYTNLHEVPYPDPRIGNFTIQNVFPQSDGDSS 476
             ++N   P  K   F      + +     +    E+   +  +G FT+  + P   G   
Sbjct: 1462 INRNTTIPTKKSQVFSTAADGQTQVEIKVHQGEREMANDNKLLGQFTLVGIPPAPRG-VP 1638

Query: 477  KVKVKVRINIHGIFSVAS 494
            +V+V   I+ +GI +V++
Sbjct: 1639 QVEVTFDIDANGIVNVSA 1692
>18301
          Length = 752

 Score =  134 bits (336), Expect = 2e-31,   Method: Compositional matrix adjust.
 Identities = 66/126 (52%), Positives = 90/126 (71%), Gaps = 2/126 (1%)
 Frame = +3

Query: 374 RGCALQCAILSPAFKVREFSITDLVPYSVTLRW--KTSFEEGTGECEVFSKNHPAPFSKV 431
           RGCALQCAILSP F+VR+FS+TD   Y++TL W  +   +E +   +V  + H  P SK+
Sbjct: 3   RGCALQCAILSPTFRVRDFSVTDCQTYTITLTWVPQNQMDEDS-RVDVLPQFHHIPASKM 179

Query: 432 ITFHKKEPFELEAFYTNLHEVPYPDPRIGNFTIQNVFPQSDGDSSKVKVKVRINIHGIFS 491
           +TF++KEPF L A YT    VP+P  +IG F I NV  Q++G+SSKVKVKVRIN + IFS
Sbjct: 180 LTFYRKEPFVLNAVYTQPANVPFPSAQIGEFKITNVTAQANGESSKVKVKVRINGNSIFS 359

Query: 492 VASASV 497
           V++A++
Sbjct: 360 VSAATM 377
>37715
          Length = 468

 Score = 75.1 bits (183), Expect(2) = 1e-20,   Method: Compositional matrix adjust.
 Identities = 31/78 (39%), Positives = 57/78 (73%)
 Frame = -2

Query: 110 RPFAIEQVTGMLLAKLKETSENALKKPVADCVISIPSFFTDAERRSVMAAAQVAGLNCLR 169
           + FA E+++ M+L K+++ +E  L K + + V+++P++F DA+R++   A  +AGLN +R
Sbjct: 398 KTFAPEEISAMVLGKMRDIAEAYLGKKIDNAVVTVPAYFNDAQRQATKDAGTIAGLNVMR 219

Query: 170 LMNETTAVALAYGIYKQD 187
           ++NE TA A+AYG+ K+D
Sbjct: 218 IINEPTAAAIAYGLDKRD 165

 Score = 43.9 bits (102), Expect(2) = 1e-20,   Method: Composition-based stats.
 Identities = 17/48 (35%), Positives = 31/48 (64%)
 Frame = -1

Query: 197 NVVFIDMGHSAYQVSVCAFNKGKLKVLATTFDPYLGGRNFDEALVDYF 244
           N++  D+G   + VS+   + G  +V+AT  D +LGG +FD+ ++D+F
Sbjct: 156 NILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMDHF 13
>27378
          Length = 410

 Score = 98.6 bits (244), Expect = 1e-20,   Method: Compositional matrix adjust.
 Identities = 51/137 (37%), Positives = 88/137 (64%), Gaps = 1/137 (0%)
 Frame = -1

Query: 247 EFKTKYKINVKENSRALLRLYQECEKLKKLMSANASDLPLNIECFMNDLDVSSKMNRAQF 306
           EFK KYK +++ N RAL RL    E+ K+ +S++ ++  + ++      D  +K++RA+F
Sbjct: 410 EFKRKYKKDLRSNPRALRRLRTAAERAKRTLSSS-TEATIEVDALFEGHDFYTKISRARF 234

Query: 307 EQLCASLLARVEPPLKSVMDQANLQREDINSIEIVGGATRIPAVKEQVTRFF-LKDISTT 365
           E+LCA L  +   P++  ++ A + ++ I+ I +VGG+TRIP V+  + +FF  K ++ +
Sbjct: 233 EELCADLFRQTLAPVEKALNDAKMDKQMIHDIVLVGGSTRIPKVQNLLQQFFGGKSLNLS 54

Query: 366 LNADEAVARGCALQCAI 382
           +N DEAVA G A+Q AI
Sbjct: 53  INPDEAVAYGAAVQAAI 3
>20979
          Length = 976

 Score = 90.9 bits (224), Expect = 2e-18,   Method: Compositional matrix adjust.
 Identities = 51/154 (33%), Positives = 89/154 (57%), Gaps = 3/154 (1%)
 Frame = +1

Query: 240 LVDYFCDEF--KTKYKINVKENSRALLRLYQECEKLKKLMSANASDLPLNIECFMNDLDV 297
           L D+    F  + K    +++N RA+ +L +E E++KK++SAN SD    +E  +   D 
Sbjct: 91  LRDHLAKVFNGQKKRSFKLEDNPRAMAKLLKEAERVKKVLSAN-SDHKAQVEGLVEGEDF 267

Query: 298 SSKMNRAQFEQLCASLLARVEPPLKSVMDQANLQREDINSIEIVGGATRIPAVKEQVTRF 357
           ++K++R  + +L   LLARV  P++  +  + +   +I  I ++GG +R+P V+E++ +F
Sbjct: 268 AAKVSREDYLELIKDLLARVTKPMEDALKVSEITMPEITEIILMGGGSRVPRVQEELLKF 447

Query: 358 FLK-DISTTLNADEAVARGCALQCAILSPAFKVR 390
             K D+  ++N DEA A G   Q A L   FKV+
Sbjct: 448 SGKSDLGKSINTDEAAALGAVYQAAYLGKGFKVK 549
>03996
          Length = 1105

 Score = 83.6 bits (205), Expect = 3e-16,   Method: Compositional matrix adjust.
 Identities = 61/215 (28%), Positives = 104/215 (48%), Gaps = 21/215 (9%)
 Frame = -2

Query: 308  QLCASLLARVEPPLKSVMDQANLQREDINSIEIVGGATRIPAVKEQVTRFFLK-DISTTL 366
            +L   LLARV  P++  +  + +   +I  I ++GG +R+P V+E++ +F  K D+  ++
Sbjct: 1056 ELIKDLLARVTKPMEDALKVSEITMPEITEIILMGGGSRVPRVQEELLKFSGKSDLGKSI 877

Query: 367  NADEAVARGCALQCAILSPAFKVREFSITD--LVPYSVTLRWKTSFEEGTGECE-----V 419
            N DEA A G   Q A L   FKV+ F + D  + P +V    + S E+           +
Sbjct: 876  NTDEAAALGAVYQAAYLGKGFKVKTFHVRDANIYPINVEFEKQKSEEDSATSARTIKRTL 697

Query: 420  FSKNHPAPFSKVITFHKK-EPFELEAFYTNLHEVPYPDPR------IGNFTIQNVFPQ-- 470
            F + +P P  KV+TF+K  + F  E  Y +L  +P  + +      + N +++ V     
Sbjct: 696  FGRMNPYPQRKVMTFNKHFKDFNFEVRYGDLDFIPEEEQKSLSARLLSNVSLEGVESXYG 517

Query: 471  ---SDGDSSKVKVKVRINIHGIFSVASA-SVIEKQ 501
                + +   VK   R++  GI  +    SV EKQ
Sbjct: 516  KLGEEAEYKGVKAHFRMDESGILHLEKVESVFEKQ 412
>12271
          Length = 1762

 Score = 76.3 bits (186), Expect = 5e-14,   Method: Compositional matrix adjust.
 Identities = 46/140 (32%), Positives = 75/140 (53%), Gaps = 8/140 (5%)
 Frame = +2

Query: 296 DVSSKMNRAQFEQLCASLLARVEPPLKSVMDQANLQREDINSIEIVGGATRIPAVKEQVT 355
           D S K+ R ++  L   LL RV  P++ V+  + +   +I  I ++GG +R+P + E + 
Sbjct: 41  DFSCKVTRDKYLHLIQDLLDRVTLPVQQVLTASQITWAEITEIILMGGGSRLPKIHEILL 220

Query: 356 RF-FLKDISTTLNADEAVARGCALQCAILSPAFKVREFSITD--LVPYSVTLRWKTSFEE 412
            +   K++  +LN DEA A G   Q A L+  FKV+ F + D  L P +V    +T+ EE
Sbjct: 221 DYSGKKELGKSLNTDEAGALGAVYQAAYLAKGFKVKTFHVRDANLFPINVEFAKQTTNEE 400

Query: 413 GTGECEV-----FSKNHPAP 427
           G+ E +V     F ++H  P
Sbjct: 401 GSEEVKVIQRTLFGRSHYFP 460
>13300
          Length = 453

 Score = 72.8 bits (177), Expect = 5e-13,   Method: Composition-based stats.
 Identities = 44/144 (30%), Positives = 78/144 (54%), Gaps = 14/144 (9%)
 Frame = +3

Query: 152 ERRSVMAAAQVAGLNCLRLMNETTAVALAYGIYKQDLPSLDEKPRNVVFIDMGHSAYQVS 211
           ERR++M AA   G+N L+LM ++ AVAL YG++++   + +   +  +F DMG ++   +
Sbjct: 3   ERRAIMTAADXVGINVLQLMTDSAAVALNYGVFRRK--NFNTTAQYYMFYDMGATSTVAT 176

Query: 212 VCAFNKGKLK------------VLATTFDPYLGGRNFDEALVDYFCDEF--KTKYKINVK 257
           V ++   K+K            +    FD  LGG      L D+    F  + K    ++
Sbjct: 177 VVSYQVVKVKEGTRVESNPQLTIKGVGFDRTLGGLEMTLRLRDHLAKVFNGQKKRSFKLE 356

Query: 258 ENSRALLRLYQECEKLKKLMSANA 281
           +N RA+ +L +E E++KK++SAN+
Sbjct: 357 DNPRAMAKLLKEAERVKKVLSANS 428
>19659
          Length = 1520

 Score = 65.1 bits (157), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 47/170 (27%), Positives = 87/170 (51%), Gaps = 8/170 (4%)
 Frame = -1

Query: 677  RLQELKKYGQPIQMKY-VEHEERPKALNDLGKKIQLVLKVIEAHRNKDERYDHLDPAEME 735
            RL+     G P+Q    V H  RP   +   +      +V++ +   +E+Y HLD +++E
Sbjct: 1505 RLRNGPASGGPLQRGTGVAHGPRPVWSSSHARS-----QVLDQYAAGEEKYAHLDKSDVE 1341

Query: 736  RVEKYISDSMNWLNSKMNAQNKLSLTQDPVVKVSEIVTKSKELDNFCNPIVY---KPKPK 792
            +V+K + D M W   KM AQ+++    +PV+ VS+++ + K L++ C+PI+         
Sbjct: 1340 KVQKCLDDKMAWWGPKMEAQSRIKPYDNPVLLVSQVMAEKKVLESTCHPIINKPKPKVEP 1161

Query: 793  VEAPEDKAKTGSEHNGPMDG----QSGSETSPDPPKGSSQHTDSGEMEVD 838
             +  +   +  S ++G  D     Q  ++ +P  P  +SQ   +GEM+VD
Sbjct: 1160 PKEEKKAEEAASANSGSGDPTQQEQPAADATPS-PDSTSQEAKTGEMDVD 1014
>09881
          Length = 600

 Score = 59.7 bits (143), Expect = 4e-09,   Method: Composition-based stats.
 Identities = 28/81 (34%), Positives = 47/81 (58%)
 Frame = +3

Query: 1   MSVVGIDLGFLNCYIAVARSGGIETIANEYSDRCTPACISLGSRTRAIGNAAKSQIVTNV 60
           M+  G+ LG  +  +AV + G     AN+  DR TP  ++  +    +G +AK  IV+NV
Sbjct: 180 MAAYGVHLGTCSACLAVYKDGKTSVAANDAGDRSTPCVVAFTACDAEVGASAKQGIVSNV 359

Query: 61  RNTIHGFKKLHGRSFDDPIVQ 81
           +NT+   K++ G +F+DP+ Q
Sbjct: 360 KNTVCNVKRILGLTFEDPVTQ 422

 Score = 43.5 bits (101), Expect = 4e-04,   Method: Composition-based stats.
 Identities = 23/49 (46%), Positives = 33/49 (67%)
 Frame = +2

Query: 135 KPVADCVISIPSFFTDAERRSVMAAAQVAGLNCLRLMNETTAVALAYGI 183
           K + D V+++PS F+D +R +  AAA  AG   LRL+NE +A ALAY +
Sbjct: 5   KGIQDAVLAVPSDFSDKQRAAASAAASKAGFKVLRLINECSAAALAYDL 151
>30255
          Length = 1761

 Score = 57.8 bits (138), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 45/167 (26%), Positives = 82/167 (49%), Gaps = 6/167 (3%)
 Frame = -1

Query: 335  INSIEIVGGATRIPAVKEQVTRFF-LKDISTTLNADEAVARGCALQCAIL--SPAFKVRE 391
            I+ I +VGG+TRIP +++ +  FF  K++  ++N DEAVA G  +Q AIL    + +V++
Sbjct: 1635 IHEIVLVGGSTRIPKIQKLLQDFFNGKELCKSINPDEAVAYGACVQAAILHGDKSEEVQD 1456

Query: 392  FSITDLVPYSVTLRWKTSFEEGTGECEVFSKNHPAPFSKVITF---HKKEPFELEAFYTN 448
              + D+ P S+ +        G     +  +N   P  +  TF      +P  L   Y  
Sbjct: 1455 LLLLDVAPLSMGIETA-----GGVMTALIKRNTTIPTKQTQTFTTYSDNQPGVLIQVYEG 1291

Query: 449  LHEVPYPDPRIGNFTIQNVFPQSDGDSSKVKVKVRINIHGIFSVASA 495
               +   +  +G F +  + P   G   +++V   I+ +GI +V++A
Sbjct: 1290 ERAMTRDNNLLGKFELTGIPPAPRG-VPQIEVTFDIDANGILNVSAA 1153
>20381
          Length = 456

 Score = 55.1 bits (131), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 43/142 (30%), Positives = 71/142 (50%), Gaps = 9/142 (6%)
 Frame = +2

Query: 673 VYVDRLQELKKYGQPIQMKYVEHEERPKALNDLGKKIQLV---LKVIEAHRNKDERYDHL 729
           V++++L+E K   + IQ++  E EERPKAL  L   +      LK +  H   D +    
Sbjct: 2   VFINKLKEAKDLMKNIQLRVYEKEERPKALAALKHHLNATDHFLKTV--HNMTDPQDPMF 175

Query: 730 DPAEMERVEKYISDSMNWLNSKMNAQNKLSLTQDPVVKVSEIVTKSKELDNFCNPIV--- 786
            P E+  +EK I+++  W +  +  Q K+   Q+P + V  I +K   L+     ++   
Sbjct: 176 TPVELATLEKLINETTAWRDEALAEQAKVPDHQNPTLLVGAIGSKIYALEREMKYLINKA 355

Query: 787 --YKPKPKVEAPEDKA-KTGSE 805
             Y+PKPK +    KA KT S+
Sbjct: 356 KNYRPKPKTDNSTAKANKTSSD 421
>31218
          Length = 322

 Score = 51.2 bits (121), Expect = 2e-06,   Method: Composition-based stats.
 Identities = 32/106 (30%), Positives = 57/106 (53%)
 Frame = +2

Query: 228 DPYLGGRNFDEALVDYFCDEFKTKYKINVKENSRALLRLYQECEKLKKLMSANASDLPLN 287
           D +LGG +FD+ LVDY     K K   +V+ ++RA+ RL +  EK K+ +S+  S   ++
Sbjct: 2   DTHLGGEDFDQRLVDYLVKLIKQKTGRDVRHDTRAMSRLRRSAEKAKRALSSQHST-KVD 178

Query: 288 IECFMNDLDVSSKMNRAQFEQLCASLLARVEPPLKSVMDQANLQRE 333
           ++   +DL     + RA+FE+L   L       +K  ++ +   R+
Sbjct: 179 LDGVTSDL-ADLTLTRAKFEELNTDLFRSTLTTVKRALEDSGKGRK 313
>12634
          Length = 877

 Score = 29.6 bits (65), Expect = 5.7,   Method: Composition-based stats.
 Identities = 15/33 (45%), Positives = 18/33 (54%), Gaps = 5/33 (15%)
 Frame = -2

Query: 793 VEAPEDKAKTGSE-----HNGPMDGQSGSETSP 820
           V APE +A +G E     H GP D Q  SE +P
Sbjct: 792 VHAPESQAVSGEETPPAAHQGPQDNQHRSEAAP 694
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|89886486|ref|NP_001034967.1| zinedin isoform 2 [Mus
musculus]
         (753 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

04732                                                                 161   7e-40
21105                                                                 152   3e-37
09899                                                                 149   3e-36
02147                                                                  64   3e-10
30256                                                                  59   8e-09
27465                                                                  57   2e-08
13335                                                                  55   9e-08
19949                                                                  55   9e-08
12806                                                                  53   4e-07
19498                                                                  53   5e-07
00561                                                                  52   9e-07
01598                                                                  52   1e-06
17598                                                                  50   5e-06
03387                                                                  49   7e-06
01249                                                                  49   9e-06
01327                                                                  48   1e-05
17602                                                                  47   3e-05
03156                                                                  45   2e-04
00825                                                                  44   2e-04
30176                                                                  43   5e-04
03395                                                                  43   5e-04
02948                                                                  43   5e-04
01462                                                                  42   7e-04
13278                                                                  42   0.001
19140                                                                  41   0.002
02090                                                                  41   0.002
21921                                                                  40   0.003
07741                                                                  40   0.004
15780                                                                  39   0.008
18981                                                                  39   0.011
04358                                                                  38   0.012
12574                                                                  38   0.018
01805                                                                  37   0.027
15118                                                                  37   0.028
11493                                                                  37   0.031
14555                                                                  37   0.043
21763                                                                  36   0.050
20662                                                                  36   0.051
37180                                                                  36   0.055
26939                                                                  35   0.097
26107                                                                  35   0.11 
04524                                                                  35   0.11 
31474                                                                  35   0.16 
38362                                                                  34   0.17 
12140                                                                  34   0.19 
12960                                                                  34   0.21 
15337                                                                  34   0.22 
30295                                                                  33   0.32 
19863                                                                  33   0.35 
38039                                                                  33   0.45 
08679                                                                  33   0.48 
16199                                                                  33   0.56 
02960                                                                  33   0.60 
25930                                                                  32   0.64 
10264                                                                  32   0.67 
27681                                                                  32   0.82 
30297                                                                  32   0.96 
06576                                                                  32   1.00 
11915                                                                  32   1.1  
16360                                                                  32   1.1  
34511                                                                  32   1.2  
34005                                                                  32   1.2  
03044                                                                  30   3.2  
12841                                                                  29   5.6  
15745                                                                  29   6.0  
01768                                                                  29   7.8  
>04732
          Length = 963

 Score =  161 bits (408), Expect = 7e-40,   Method: Compositional matrix adjust.
 Identities = 85/151 (56%), Positives = 102/151 (67%), Gaps = 9/151 (5%)
 Frame = -2

Query: 63  LSLPGILHFIQHXXXXXXXXXXXXXXXXXXLQAQVAFLQGERKGQENLKTDLVRRIKMLE 122
            S+PGILHF+Q                   LQA++AFLQGERKGQENLK DLVRRIKMLE
Sbjct: 902 FSMPGILHFLQTEWARFEMERSQWEVERAELQARIAFLQGERKGQENLKQDLVRRIKMLE 723

Query: 123 YALKQERAKYHKLKFGTDLNQG-------EKKTD--LSEQVSNGPVESVTLENSPLVWKE 173
           +ALKQER KYHKLK+GTD+N         EKK D  + E   + P       N+ + WK+
Sbjct: 722 FALKQERGKYHKLKYGTDMNSDELTQSSYEKKDDDQMGEPAMSSPA------NTNIEWKQ 561

Query: 174 GRQLLRQYLEEVGYTDTILDMRSKRVRSLLG 204
           GRQLLRQYL+E+GY+DTI+D+RS RVRSLLG
Sbjct: 560 GRQLLRQYLQEIGYSDTIIDVRSARVRSLLG 468
>21105
          Length = 650

 Score =  152 bits (385), Expect = 3e-37,   Method: Composition-based stats.
 Identities = 71/117 (60%), Positives = 88/117 (75%)
 Frame = +1

Query: 637 PAQINQVVSHPSQPLTITAHDDRGIRFLDNRTGKSVHSMVAHLDAVTCLAVDPNGVFLMS 696
           P Q++    HP+ P+TITAH+DR IRF DN TGK +H+MVAHLD+VT LAVDPNG++L+S
Sbjct: 70  PDQLHH--QHPTMPITITAHEDRHIRFFDNNTGKLIHAMVAHLDSVTSLAVDPNGLYLLS 243

Query: 697 GSHDCSLRLWSLDNKTCVQEITAHRKKHEEAIHAVACHPXXXXXXXXXXXXXXXVFV 753
           GSHDCS+RLW+LD+KTCVQEIT+HRKK +E+IH VA HP               VFV
Sbjct: 244 GSHDCSIRLWNLDSKTCVQEITSHRKKFDESIHDVAFHPQKPYIASAGADALAKVFV 414

 Score = 31.2 bits (69), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 24/88 (27%), Positives = 38/88 (43%)
 Frame = +1

Query: 484 IHAFRAHRGPVLAVTMGSNSEYCYSGGADARIHSWKIPDLNMDPYDGYDPSVLSHVLEGH 543
           IHA  AH   V ++ +  N  Y  SG  D  I  W     N+D        + SH  +  
Sbjct: 169 IHAMVAHLDSVTSLAVDPNGLYLLSGSHDCSIRLW-----NLDSKTCVQ-EITSH-RKKF 327

Query: 544 GDAVWGLAFSPTSQRLASCSADGTVRIW 571
            +++  +AF P    +AS  AD   +++
Sbjct: 328 DESIHDVAFHPQKPYIASAGADALAKVF 411

 Score = 29.6 bits (65), Expect = 4.4,   Method: Composition-based stats.
 Identities = 24/82 (29%), Positives = 33/82 (40%), Gaps = 4/82 (4%)
 Frame = +1

Query: 436 SHYDGIRSLAFHHSQSALLTASEDGTLKLWNLQKAVTAKK----NAALDVEPIHAFRAHR 491
           +H D + SLA   +   LL+ S D +++LWNL      ++        D E IH    H 
Sbjct: 184 AHLDSVTSLAVDPNGLYLLSGSHDCSIRLWNLDSKTCVQEITSHRKKFD-ESIHDVAFH- 357

Query: 492 GPVLAVTMGSNSEYCYSGGADA 513
                        Y  S GADA
Sbjct: 358 ---------PQKPYIASAGADA 396
>09899
          Length = 1401

 Score =  149 bits (377), Expect = 3e-36,   Method: Compositional matrix adjust.
 Identities = 76/116 (65%), Positives = 91/116 (78%), Gaps = 4/116 (3%)
 Frame = +1

Query: 93  LQAQVAFLQGERKGQENLKTDLVRRIKMLEYALKQERAKYHKLKFGTDLNQGEKKTDLSE 152
           LQA++AFLQGERKGQENLK DLVRRIKMLE+ALKQER KYHKLK+GTD+N  + K  + E
Sbjct: 151 LQARIAFLQGERKGQENLKQDLVRRIKMLEFALKQERGKYHKLKYGTDMNPEDLKPPVFE 330

Query: 153 QVS----NGPVESVTLENSPLVWKEGRQLLRQYLEEVGYTDTILDMRSKRVRSLLG 204
           +      +G     +  NS   WK+GRQLLRQYL+E+GYTDTI+D+RS RVRSLLG
Sbjct: 331 KKDEDQLDGEPSMTSSANSNTQWKQGRQLLRQYLQEIGYTDTIIDVRSARVRSLLG 498

 Score = 34.3 bits (77), Expect = 0.20,   Method: Composition-based stats.
 Identities = 12/17 (70%), Positives = 16/17 (94%)
 Frame = +3

Query: 431  KFTLRSHYDGIRSLAFH 447
            K+TLRSH+DG+R+LAF 
Sbjct: 1329 KYTLRSHFDGVRALAFQ 1379
>02147
          Length = 1547

 Score = 63.5 bits (153), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 58/274 (21%), Positives = 101/274 (36%)
 Frame = +2

Query: 433 TLRSHYDGIRSLAFHHSQSALLTASEDGTLKLWNLQKAVTAKKNAALDVEPIHAFRAHRG 492
           T   H   +     +   +   T + D + K+W+ +K            E +  F +H+ 
Sbjct: 158 TFEGHKGAVWGATLNREATRAATGAADFSAKIWDAEKG-----------EELQTF-SHKH 301

Query: 493 PVLAVTMGSNSEYCYSGGADARIHSWKIPDLNMDPYDGYDPSVLSHVLEGHGDAVWGLAF 552
            V +V    +     +G  +  +  + + + + +P              GH   + G  F
Sbjct: 302 IVKSVDFSHDGTALLTGSNEKLLKVFDLVNTDAEP----------KSFAGHTSNIKGALF 451

Query: 553 SPTSQRLASCSADGTVRIWDPSSSGPSCLCTFPMDGEHGIPTSVAFTSTEPAHVVASFRS 612
               +R+ S S D TVR+W   +       TF        PTS+  +  +   +V    S
Sbjct: 452 LSDGKRIISASDDKTVRLWSLETCQEVQQLTFDTP-----PTSLTLSPDKNTIIVT--HS 610

Query: 613 GDTVLYDLEAGSALLTLESRGSSGPAQINQVVSHPSQPLTITAHDDRGIRFLDNRTGKSV 672
            +   Y  +    +   E+      A I+    H S+   +   +D  +   D  TGK +
Sbjct: 611 QNIAFYQADTLREMKKFEAE-----APISSASLHQSERFFVAGGEDFKMYKFDYETGKEI 775

Query: 673 HSMVAHLDAVTCLAVDPNGVFLMSGSHDCSLRLW 706
            S   H   V C+   P+G    SGS D +LRLW
Sbjct: 776 ESFKGHFGPVHCVRFSPDGELYASGSEDGTLRLW 877
>30256
          Length = 961

 Score = 58.9 bits (141), Expect = 8e-09,   Method: Compositional matrix adjust.
 Identities = 63/252 (25%), Positives = 101/252 (40%), Gaps = 1/252 (0%)
 Frame = +3

Query: 478 ALDVEPIHAFRAHRGPVLAVTMGSNSEYCYSGGADARIHSWKIPDLNMDPYDGYDPSVLS 537
           A+    I     H G V +  M  N+    SG  D  +  W             D  V +
Sbjct: 3   AVTGRCIKNLIGHTGGVWSSQMTGNTVI--SGSTDRSLKVWNA-----------DTGVCT 143

Query: 538 HVLEGHGDAVWGLAFSPTSQRLASCSADGTVRIWDPSSSGPSCLCTFPMDGEHGIPTSVA 597
           H L GH   V  L+ S   +++ S S D T+R+WD  S      C   + G       V 
Sbjct: 144 HTLYGHSSTVRCLSLS--GKKVVSGSRDATLRVWDIESGH----CLNVLLGHMAAVRCVQ 305

Query: 598 FTSTEPAHVVASFRSGDTVLYDLEAGSALLTLESRGSSGPAQINQVVSHPSQPLTITAHD 657
           +   +   VV+        ++D +  S L TL+          N+V S     + + +  
Sbjct: 306 Y---DGKRVVSGAXDYTVRVWDPDTASCLHTLQ-------GHTNRVYSLQFDGVYVVSGS 455

Query: 658 -DRGIRFLDNRTGKSVHSMVAHLDAVTCLAVDPNGVFLMSGSHDCSLRLWSLDNKTCVQE 716
            D  IR  D R GK VH+++ H    + L +  N   L+SG+ D ++++W +    C+Q 
Sbjct: 456 LDTSIRVWDVRCGKLVHTLMGHQSLTSGLELKDN--LLVSGNADSTVKVWDVHTGKCLQT 629

Query: 717 ITAHRKKHEEAI 728
           +     KH  A+
Sbjct: 630 LLG-PNKHRSAV 662

 Score = 37.4 bits (85), Expect = 0.022,   Method: Compositional matrix adjust.
 Identities = 49/218 (22%), Positives = 92/218 (42%), Gaps = 12/218 (5%)
 Frame = +3

Query: 426 KTWNPK-----FTLRSHYDGIRSLAFHHSQSALLTASEDGTLKLWNLQKAVTAKKNAALD 480
           + W+P       TL+ H + + SL F      +++ S D ++++W+++            
Sbjct: 351 RVWDPDTASCLHTLQGHTNRVYSLQF--DGVYVVSGSLDTSIRVWDVRCG---------- 494

Query: 481 VEPIHAFRAHRGPVLAVTMGSNSEYCYSGGADARIHSWKIPDLNMDPYDGYDPSVLSHVL 540
            + +H    H+     + +  N     SG AD+ +  W          D +    L  +L
Sbjct: 495 -KLVHTLMGHQSLTSGLELKDN--LLVSGNADSTVKVW----------DVHTGKCLQTLL 635

Query: 541 --EGHGDAVWGLAFSPTSQRLASCSADGTVRIWDPSSSG-PSCLCTFPMDGEHGIPTSVA 597
               H  AV  L F+   + + +CS DGTV++WD ++      L T P  G  G+   + 
Sbjct: 636 GPNKHRSAVTCLQFNK--KFVVTCSDDGTVKLWDLNTGDFIRNLITLPSGGSGGVVWRLR 809

Query: 598 FTSTEPAHVVASFRSG----DTVLYDLEAGSALLTLES 631
             +T+    V S R+G      ++ D +  +A L+ E+
Sbjct: 810 CNNTKMVCAVGS-RNGTEETKLLVLDFDQVNARLSYEA 920
>27465
          Length = 658

 Score = 57.4 bits (137), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 38/140 (27%), Positives = 60/140 (42%), Gaps = 1/140 (0%)
 Frame = -1

Query: 434 LRSHYDGIRSLAFHHSQSALLTASEDGTLKLWNLQKAVTAKKNAALDVEPIHAFRAHRGP 493
           LR+H   + ++AF+ S S+ +T S D T K+W+   A           E +H    HR  
Sbjct: 373 LRAHILPLTNVAFNKSGSSFITGSYDRTCKIWDTASA-----------EELHTLEGHRNV 227

Query: 494 VLAVTMGS-NSEYCYSGGADARIHSWKIPDLNMDPYDGYDPSVLSHVLEGHGDAVWGLAF 552
           V A+   +   +   +G  D     W   D               H L GH   +  ++F
Sbjct: 226 VYAIAFNNPFGDKVITGSFDKTCKLWSTAD-----------GKCYHTLRGHTAEIVCVSF 80

Query: 553 SPTSQRLASCSADGTVRIWD 572
           +P+S  +A+ S D T R+WD
Sbjct: 79  NPSSTLIATGSMDTTCRLWD 20

 Score = 32.7 bits (73), Expect = 0.57,   Method: Compositional matrix adjust.
 Identities = 15/38 (39%), Positives = 24/38 (63%)
 Frame = -1

Query: 433 TLRSHYDGIRSLAFHHSQSALLTASEDGTLKLWNLQKA 470
           TLR H   I  ++F+ S + + T S D T +LW+++KA
Sbjct: 121 TLRGHTAEIVCVSFNPSSTLIATGSMDTTCRLWDVEKA 8
>13335
          Length = 863

 Score = 55.5 bits (132), Expect = 9e-08,   Method: Compositional matrix adjust.
 Identities = 61/243 (25%), Positives = 101/243 (41%), Gaps = 16/243 (6%)
 Frame = +1

Query: 489 AHRGPVLAVTMGSNSEYCYSGGADARIHSWKIPDLNMDPYDGYDPSVLSHVLEGHGDAVW 548
           A +  +       +S +  SG  D  I  W++    +         V S+V  GH D+V 
Sbjct: 55  ASKSSIRVCKFSPSSSHLVSGSDDDTICMWEVATQKL---------VRSYV--GHEDSVM 201

Query: 549 GLAFSPTSQRLASCSADGTVRIWDPSSSGPSCLCTFPMDGEHGIPTSVAFTSTEPAHVVA 608
            LA+SP    L S S +G + +WD S      L T  +D      T   F+ T       
Sbjct: 202 ALAYSPNGHYLVSGSPNGDLYVWDASFGHCRHL-TLRVDAHDLGVTCCEFSPTFGTACAE 378

Query: 609 SFRSGDTVL-------------YDLEAGSALLTLESRGS-SGPAQINQVVSH-PSQPLTI 653
           +  + + +L             +  + GS  +TL+ R   SG + +    +  PS  L  
Sbjct: 379 NSSTCNLLLATGGKDNLIKLWTFSAQVGSPEVTLQCRDILSGHSDLVMACAFSPSSALLA 558

Query: 654 TAHDDRGIRFLDNRTGKSVHSMVA-HLDAVTCLAVDPNGVFLMSGSHDCSLRLWSLDNKT 712
           +   D+ +R  D+  G ++ S+ A H   VTC A   +G  L SGS D  +++W L + +
Sbjct: 559 SGSFDKSVRLWDSVKGVALFSIEACHSRFVTCCAFSIDGTLLASGSMDRIIKIWKLTDTS 738

Query: 713 CVQ 715
            + 
Sbjct: 739 SIM 747

 Score = 54.7 bits (130), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 46/173 (26%), Positives = 67/173 (38%), Gaps = 21/173 (12%)
 Frame = +1

Query: 437 HYDGIRSLAFHHSQSALLTASEDGTLKLWNLQKAVTAKKNAALDVEPIHAFRAHRGPVLA 496
           H D + +LA+  +   L++ S +G L +W+            +D   +        P   
Sbjct: 184 HEDSVMALAYSPNGHYLVSGSPNGDLYVWDASFGHCRHLTLRVDAHDLGVTCCEFSPTFG 363

Query: 497 VTMGSNSEYC----YSGGADARIHSWKI------PDLNMDPYDGYDPSVLSHVLEGHGDA 546
                NS  C     +GG D  I  W        P++ +   D         +L GH D 
Sbjct: 364 TACAENSSTCNLLLATGGKDNLIKLWTFSAQVGSPEVTLQCRD---------ILSGHSDL 516

Query: 547 VWGLAFSPTSQRLASCSADGTVRIWDPSS-----SGPSC------LCTFPMDG 588
           V   AFSP+S  LAS S D +VR+WD        S  +C       C F +DG
Sbjct: 517 VMACAFSPSSALLASGSFDKSVRLWDSVKGVALFSIEACHSRFVTCCAFSIDG 675
>19949
          Length = 903

 Score = 55.1 bits (131), Expect = 9e-08,   Method: Compositional matrix adjust.
 Identities = 41/152 (26%), Positives = 66/152 (43%)
 Frame = +2

Query: 549 GLAFSPTSQRLASCSADGTVRIWDPSSSGPSCLCTFPMDGEHGIPTSVAFTSTEPAHVVA 608
            L F P     AS S D  V++WD    G    C +   G  G    + F S +   + +
Sbjct: 8   SLDFHPYGAYTASGSMDCNVKLWDIRRKG----CIYTYKGHTGCVCCLRF-SPDGRWIAS 172

Query: 609 SFRSGDTVLYDLEAGSALLTLESRGSSGPAQINQVVSHPSQPLTITAHDDRGIRFLDNRT 668
           +   G   L+DL AG  L  L+    +    +N +  HP + L  +   DR ++F D  T
Sbjct: 173 ASEDGLVKLWDLTAGKLLTDLKLHRDA----VNTIEFHPHEFLLASGSADRTVKFWDLET 340

Query: 669 GKSVHSMVAHLDAVTCLAVDPNGVFLMSGSHD 700
            + + +     +++  +   P+GV L SGS D
Sbjct: 341 FQLISTTEPEANSIRSILFHPDGVCLYSGSKD 436

 Score = 45.4 bits (106), Expect = 9e-05,   Method: Compositional matrix adjust.
 Identities = 23/90 (25%), Positives = 41/90 (45%)
 Frame = +2

Query: 646 HPSQPLTITAHDDRGIRFLDNRTGKSVHSMVAHLDAVTCLAVDPNGVFLMSGSHDCSLRL 705
           HP    T +   D  ++  D R    +++   H   V CL   P+G ++ S S D  ++L
Sbjct: 20  HPYGAYTASGSMDCNVKLWDIRRKGCIYTYKGHTGCVCCLRFSPDGRWIASASEDGLVKL 199

Query: 706 WSLDNKTCVQEITAHRKKHEEAIHAVACHP 735
           W L     + ++  HR    +A++ +  HP
Sbjct: 200 WDLTAGKLLTDLKLHR----DAVNTIEFHP 277

 Score = 45.1 bits (105), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 34/132 (25%), Positives = 54/132 (40%)
 Frame = +2

Query: 441 IRSLAFHHSQSALLTASEDGTLKLWNLQKAVTAKKNAALDVEPIHAFRAHRGPVLAVTMG 500
           ++SL FH   +   + S D  +KLW++++              I+ ++ H G V  +   
Sbjct: 2   VKSLDFHPYGAYTASGSMDCNVKLWDIRRKGC-----------IYTYKGHTGCVCCLRFS 148

Query: 501 SNSEYCYSGGADARIHSWKIPDLNMDPYDGYDPSVLSHVLEGHGDAVWGLAFSPTSQRLA 560
            +  +  S   D  +  W +               L   L+ H DAV  + F P    LA
Sbjct: 149 PDGRWIASASEDGLVKLWDLT-----------AGKLLTDLKLHRDAVNTIEFHPHEFLLA 295

Query: 561 SCSADGTVRIWD 572
           S SAD TV+ WD
Sbjct: 296 SGSADRTVKFWD 331

 Score = 35.4 bits (80), Expect = 0.078,   Method: Compositional matrix adjust.
 Identities = 14/39 (35%), Positives = 20/39 (51%)
 Frame = +2

Query: 682 VTCLAVDPNGVFLMSGSHDCSLRLWSLDNKTCVQEITAH 720
           V  L   P G +  SGS DC+++LW +  K C+     H
Sbjct: 2   VKSLDFHPYGAYTASGSMDCNVKLWDIRRKGCIYTYKGH 118

 Score = 35.4 bits (80), Expect = 0.092,   Method: Compositional matrix adjust.
 Identities = 20/82 (24%), Positives = 39/82 (47%)
 Frame = +2

Query: 654 TAHDDRGIRFLDNRTGKSVHSMVAHLDAVTCLAVDPNGVFLMSGSHDCSLRLWSLDNKTC 713
           +A +D  ++  D   GK +  +  H DAV  +   P+   L SGS D +++ W L+    
Sbjct: 170 SASEDGLVKLWDLTAGKLLTDLKLHRDAVNTIEFHPHEFLLASGSADRTVKFWDLE---- 337

Query: 714 VQEITAHRKKHEEAIHAVACHP 735
             ++ +  +    +I ++  HP
Sbjct: 338 TFQLISTTEPEANSIRSILFHP 403

 Score = 32.0 bits (71), Expect = 0.97,   Method: Compositional matrix adjust.
 Identities = 35/144 (24%), Positives = 56/144 (38%), Gaps = 2/144 (1%)
 Frame = +2

Query: 432 FTLRSHYDGIRSLAFHHSQSALLTASEDGTLKLWNLQKAVTAKKNAALDVEPIHAFRAHR 491
           +T + H   +  L F      + +ASEDG +KLW+L    TA K        +   + HR
Sbjct: 101 YTYKGHTGCVCCLRFSPDGRWIASASEDGLVKLWDL----TAGK-------LLTDLKLHR 247

Query: 492 GPVLAVTMGSNSEYCYSGGADARIHSWKIPDLNMDPYDGYDPSVLSHVLEGHGDAVWGLA 551
             V  +    +     SG AD  +  W +               L    E   +++  + 
Sbjct: 248 DAVNTIEFHPHEFLLASGSADRTVKFWDLETFQ-----------LISTTEPEANSIRSIL 394

Query: 552 FSPTSQRLASCSADGTVRI--WDP 573
           F P    L S S D T+++  W+P
Sbjct: 395 FHPDGVCLYSGSKD-TLKVYHWEP 463
>12806
          Length = 961

 Score = 53.1 bits (126), Expect = 4e-07,   Method: Compositional matrix adjust.
 Identities = 55/223 (24%), Positives = 94/223 (42%), Gaps = 2/223 (0%)
 Frame = +3

Query: 497 VTMGSNSEYCYSGGADARIHSWKI-PDLNMDPYDGYDPSVLSHVLEGHGDAVWGLAFSPT 555
           V  G+   +  SGG D  I  W + P  + D    +   V    L GH   +  LA S  
Sbjct: 27  VVDGATKPFLISGGRDNNIIVWDL*PKKDGDEDQTW--GVPRKTLTGHSHFISDLALSAD 200

Query: 556 SQRLASCSADGTVRIWD-PSSSGPSCLCTFPMDGEHGIPTSVAFTSTEPAHVVASFRSGD 614
           S+   S S D T+R+WD    S  S       D       +VAF S +   + +  R  +
Sbjct: 201 SRFALSSSWDATLRLWDIKKGSTTSRFINHTRD-----VLTVAF-SPDNRQIASGGRDKN 362

Query: 615 TVLYDLEAGSALLTLESRGSSGPAQINQVVSHPSQPLTITAHDDRGIRFLDNRTGKSVHS 674
             ++++  G    T+++   +      +       P+ ++A +D+ I+  DN T    ++
Sbjct: 363 LKIWNI-MGECKYTVDANAHTDWVTCVRFHQDTKNPIVVSASNDKTIKVWDNHTMTLKNT 539

Query: 675 MVAHLDAVTCLAVDPNGVFLMSGSHDCSLRLWSLDNKTCVQEI 717
            V H   +T L +  N  +L+SGS D     W++   + V +I
Sbjct: 540 FVGHKAQITALDMSTN--YLVSGSKDGIAMTWNVAEGSFVGKI 662

 Score = 46.2 bits (108), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 40/150 (26%), Positives = 59/150 (39%), Gaps = 3/150 (2%)
 Frame = +3

Query: 426 KTWN-PKFTLRSHYDGIRSLAFHHSQSALLTASEDGTLKLWNLQKAVTAKKNAALDVEPI 484
           +TW  P+ TL  H   I  LA        L++S D TL+LW+++K  T  +         
Sbjct: 126 QTWGVPRKTLTGHSHFISDLALSADSRFALSSSWDATLRLWDIKKGSTTSR--------- 278

Query: 485 HAFRAHRGPVLAVTMGSNSEYCYSGGADARIHSWKIPDLNMDPYDGYDPSVLSHVLEGHG 544
             F  H   VL V    ++    SGG D  +  W I        D             H 
Sbjct: 279 --FINHTRDVLTVAFSPDNRQIASGGRDKNLKIWNIMGECKYTVDA----------NAHT 422

Query: 545 DAVWGLAFSPTSQR--LASCSADGTVRIWD 572
           D V  + F   ++   + S S D T+++WD
Sbjct: 423 DWVTCVRFHQDTKNPIVVSASNDKTIKVWD 512

 Score = 31.2 bits (69), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 21/91 (23%), Positives = 35/91 (38%), Gaps = 10/91 (10%)
 Frame = +3

Query: 642 QVVSHPSQPLTITAHDDRGIRFLD----------NRTGKSVHSMVAHLDAVTCLAVDPNG 691
           QVV   ++P  I+   D  I   D             G    ++  H   ++ LA+  + 
Sbjct: 24  QVVDGATKPFLISGGRDNNIIVWDL*PKKDGDEDQTWGVPRKTLTGHSHFISDLALSADS 203

Query: 692 VFLMSGSHDCSLRLWSLDNKTCVQEITAHRK 722
            F +S S D +LRLW +   +       H +
Sbjct: 204 RFALSSSWDATLRLWDIKKGSTTSRFINHTR 296
>19498
          Length = 903

 Score = 52.8 bits (125), Expect = 5e-07,   Method: Compositional matrix adjust.
 Identities = 38/122 (31%), Positives = 55/122 (45%), Gaps = 7/122 (5%)
 Frame = -1

Query: 458 EDGTLKLWNLQKAVTAKKNAALDVEPIHA-FRAHRGPVLAVTMGSNSEYCYSGGADARIH 516
           + G + +WN+      K+ A  DV  +     +H G V  V    N ++  SGG D  I 
Sbjct: 888 DSGKVVIWNMAPIRDEKEEADDDVPRVLCQMDSHLGCVNCVRWSENGKFLASGGDDKLIM 709

Query: 517 SWKIP-DLNMDPYDGYDPSVLSH-----VLEGHGDAVWGLAFSPTSQRLASCSADGTVRI 570
            W+I          G + ++L H      L GH   V  LA+SP    LASCS D T+ +
Sbjct: 708 IWQISRGFGSGKSFGSNVTILEHWRSVATLRGHAGDVLDLAWSPQDLWLASCSVDNTIVV 529

Query: 571 WD 572
           W+
Sbjct: 528 WN 523

 Score = 40.4 bits (93), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 32/147 (21%), Positives = 56/147 (38%), Gaps = 6/147 (4%)
 Frame = -1

Query: 434 LRSHYDGIRSLAFHHSQSALLTASEDGTLKLWNLQKAVTAKKNAALDV------EPIHAF 487
           + SH   +  + +  +   L +  +D  + +W + +   + K+   +V        +   
Sbjct: 798 MDSHLGCVNCVRWSENGKFLASGGDDKLIMIWQISRGFGSGKSFGSNVTILEHWRSVATL 619

Query: 488 RAHRGPVLAVTMGSNSEYCYSGGADARIHSWKIPDLNMDPYDGYDPSVLSHVLEGHGDAV 547
           R H G VL +       +  S   D  I  W          +    S    V+ GH   V
Sbjct: 618 RGHAGDVLDLAWSPQDLWLASCSVDNTIVVW----------NALKFSEQVAVIRGHAGMV 469

Query: 548 WGLAFSPTSQRLASCSADGTVRIWDPS 574
            G+ + P  + LAS S D T+R+W  S
Sbjct: 468 KGVTWDPVGRYLASQSDDKTLRVWRTS 388

 Score = 36.2 bits (82), Expect = 0.051,   Method: Compositional matrix adjust.
 Identities = 26/95 (27%), Positives = 34/95 (35%)
 Frame = -1

Query: 428 WNPKFTLRSHYDGIRSLAFHHSQSALLTASEDGTLKLWNLQKAVTAKKNAALDVEPIHAF 487
           W    TLR H   +  LA+      L + S D T+ +WN  K            E +   
Sbjct: 639 WRSVATLRGHAGDVLDLAWSPQDLWLASCSVDNTIVVWNALKF----------SEQVAVI 490

Query: 488 RAHRGPVLAVTMGSNSEYCYSGGADARIHSWKIPD 522
           R H G V  VT      Y  S   D  +  W+  D
Sbjct: 489 RGHAGMVKGVTWDPVGRYLASQSDDKTLRVWRTSD 385

 Score = 29.6 bits (65), Expect = 4.6,   Method: Compositional matrix adjust.
 Identities = 14/44 (31%), Positives = 22/44 (50%)
 Frame = -1

Query: 665 DNRTGKSVHSMVAHLDAVTCLAVDPNGVFLMSGSHDCSLRLWSL 708
           D+   + +  M +HL  V C+    NG FL SG  D  + +W +
Sbjct: 828 DDDVPRVLCQMDSHLGCVNCVRWSENGKFLASGGDDKLIMIWQI 697
>00561
          Length = 1003

 Score = 52.0 bits (123), Expect = 9e-07,   Method: Compositional matrix adjust.
 Identities = 59/261 (22%), Positives = 103/261 (39%), Gaps = 1/261 (0%)
 Frame = -3

Query: 452 ALLTASEDGTLKLWNLQKAVTAKKNAALDVEPIHAFRAHRGPVLAVTMGSNSEYCYSGGA 511
            +++AS D TL +W L +             P      H   +  V + S+  Y  SG  
Sbjct: 968 TIISASRDKTLIVWKLTRDEDTNYG-----YPQKRLYGHSHFISDVVLSSDGNYALSGSW 804

Query: 512 DARIHSWKIPDLNMDPYDGYDPSVLSHVLEGHGDAVWGLAFSPTSQRLASCSADGTVRIW 571
           D  +  W +                +   EGH   V  +AFS  ++++ S S D T+++W
Sbjct: 803 DQTLRLWDLA-----------AGKTTRRFEGHTKDVLSVAFSADNRQIVSGSRDKTIKLW 657

Query: 572 DPSSSGPSCLCTFPMDGEHGIPTSVAFTSTEPAHVVASFRSGDTV-LYDLEAGSALLTLE 630
           +  +    C  T   DG     + V F+      ++ S     TV +++L   +  L   
Sbjct: 656 NTLA---ECKFTIQEDGHTDWVSCVRFSPNHSNPIIVSCGWDRTVKVWNL--ANCKLKNN 492

Query: 631 SRGSSGPAQINQVVSHPSQPLTITAHDDRGIRFLDNRTGKSVHSMVAHLDAVTCLAVDPN 690
             G +G   +N V   P   L  +   D      D   GK+++++  H D +  L   PN
Sbjct: 491 HHGHNG--YLNTVTVSPDGSLCTSGGKDSKALLWDLNDGKNLYTL-EHNDIINALCFSPN 321

Query: 691 GVFLMSGSHDCSLRLWSLDNK 711
             +L   ++  S+++W L  K
Sbjct: 320 RYWLCV-AYGPSIKIWDLACK 261

 Score = 48.9 bits (115), Expect = 8e-06,   Method: Compositional matrix adjust.
 Identities = 49/162 (30%), Positives = 70/162 (43%), Gaps = 9/162 (5%)
 Frame = -3

Query: 426 KTWNP----KFTLR--SHYDGIRSLAF--HHSQSALLTASEDGTLKLWNLQKAVTAKKNA 477
           K WN     KFT++   H D +  + F  +HS   +++   D T+K+WNL      K N 
Sbjct: 665 KLWNTLAECKFTIQEDGHTDWVSCVRFSPNHSNPIIVSCGWDRTVKVWNLANC-KLKNN- 492

Query: 478 ALDVEPIHAFRAHRGPVLAVTMGSNSEYCYSGGADARIHSWKIPDLNMDPYDGYDPSVLS 537
                       H G +  VT+  +   C SGG D++   W   DLN    DG +   L 
Sbjct: 491 ---------HHGHNGYLNTVTVSPDGSLCTSGGKDSKALLW---DLN----DGKNLYTLE 360

Query: 538 HVLEGHGDAVWGLAFSPTSQRLASCSADG-TVRIWDPSSSGP 578
                H D +  L FSP   R   C A G +++IWD +   P
Sbjct: 359 -----HNDIINALCFSP--NRYWLCVAYGPSIKIWDLACKKP 255

 Score = 31.6 bits (70), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 23/88 (26%), Positives = 39/88 (44%), Gaps = 7/88 (7%)
 Frame = -3

Query: 642 QVVSHPSQPLTI-TAHDDRGI------RFLDNRTGKSVHSMVAHLDAVTCLAVDPNGVFL 694
           Q+ ++P  P TI +A  D+ +      R  D   G     +  H   ++ + +  +G + 
Sbjct: 998 QIATNPKDPDTIISASRDKTLIVWKLTRDEDTNYGYPQKRLYGHSHFISDVVLSSDGNYA 819

Query: 695 MSGSHDCSLRLWSLDNKTCVQEITAHRK 722
           +SGS D +LRLW L      +    H K
Sbjct: 818 LSGSWDQTLRLWDLAAGKTTRRFEGHTK 735

 Score = 29.3 bits (64), Expect = 6.3,   Method: Compositional matrix adjust.
 Identities = 28/144 (19%), Positives = 56/144 (38%), Gaps = 2/144 (1%)
 Frame = -3

Query: 594  TSVAFTSTEPAHVVASFRSGDTVLYDL--EAGSALLTLESRGSSGPAQINQVVSHPSQPL 651
            T +A    +P  ++++ R    +++ L  +  +     + R       I+ VV       
Sbjct: 1001 TQIATNPKDPDTIISASRDKTLIVWKLTRDEDTNYGYPQKRLYGHSHFISDVVLSSDGNY 822

Query: 652  TITAHDDRGIRFLDNRTGKSVHSMVAHLDAVTCLAVDPNGVFLMSGSHDCSLRLWSLDNK 711
             ++   D+ +R  D   GK+      H   V  +A   +   ++SGS D +++LW   N 
Sbjct: 821  ALSGSWDQTLRLWDLAAGKTTRRFEGHTKDVLSVAFSADNRQIVSGSRDKTIKLW---NT 651

Query: 712  TCVQEITAHRKKHEEAIHAVACHP 735
                + T     H + +  V   P
Sbjct: 650  LAECKFTIQEDGHTDWVSCVRFSP 579
>01598
          Length = 1545

 Score = 51.6 bits (122), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 50/193 (25%), Positives = 81/193 (41%), Gaps = 16/193 (8%)
 Frame = +1

Query: 559 LASCSADGTVRIWDPSSSGPSCLCTFPMD----GEHG----IPTSVAFTSTEPAHVVASF 610
           +A+ S D T+R+W  S      +   P      G+ G    +  ++ +  + P  +V+S 
Sbjct: 109 IATGSKDRTIRVWTLSQGKQIFMKKLPNQRREAGDTGSRFKVWLAIHWLKSNPEQLVSSS 288

Query: 611 RSGDTVLYDL-----EAGSALLTLESRGSSGPAQINQVVSHPSQPLTITAHDDRGIRFLD 665
             GD +L+ L     +A     T + R    P   N   S P      T   DR +   D
Sbjct: 289 SGGDLLLWSLRYTKGQAYQTFQTSDYRPHMRPV-FNICASGPDSKTLCTFAQDRQVVLWD 465

Query: 666 NRTGKSVHSMV---AHLDAVTCLAVDPNGVFLMSGSHDCSLRLWSLDNKTCVQEITAHRK 722
             T ++V SM     H+  V    +DP  V +  G  D  +R W++ NKT   ++T   +
Sbjct: 466 LETMEAVASMATLGGHVYCVRTSPIDPGRVAV--GVGDSMIRTWNMSNKTNPYDVTTLWQ 639

Query: 723 KHEEAIHAVACHP 735
             +  + AVA HP
Sbjct: 640 GIKSKVTAVAWHP 678

 Score = 31.6 bits (70), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 17/74 (22%), Positives = 33/74 (44%), Gaps = 1/74 (1%)
 Frame = +1

Query: 448  HSQSALLTASEDGTLKLWNLQKAVTAKKNAALDVEPIHAFRAHRGPVLAVTM-GSNSEYC 506
            H  + L++   D    +W++QK              +  F+ H G +L     G + +  
Sbjct: 1333 HHDARLVSVGYDAEAFVWDVQKGTA-----------LAQFKGHMGRLLTCQFSGLDPDLV 1479

Query: 507  YSGGADARIHSWKI 520
             +GG+DA +H W++
Sbjct: 1480 MTGGSDASVHVWRV 1521
>17598
          Length = 875

 Score = 49.7 bits (117), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 48/215 (22%), Positives = 87/215 (40%), Gaps = 1/215 (0%)
 Frame = +1

Query: 504 EYCYSGGADARIHSWK-IPDLNMDPYDGYDPSVLSHVLEGHGDAVWGLAFSPTSQRLASC 562
           E+   GG D  +  W  +P  + D  + +        L+GH   V  ++ S  S+ + S 
Sbjct: 4   EFLIXGGRDKLLIVWDLVPRKDGDEDETWGGP--RRTLQGHSHFVSDVSLSADSRYVLSS 177

Query: 563 SADGTVRIWDPSSSGPSCLCTFPMDGEHGIPTSVAFTSTEPAHVVASFRSGDTVLYDLEA 622
           S D T+R+WD          T           +VAF S +   + +  R     +++   
Sbjct: 178 SWDATLRLWDIKKGNT----TRRFISHTRDALAVAF-SPDNRQIASGGRDKALKIWN-TV 339

Query: 623 GSALLTLESRGSSGPAQINQVVSHPSQPLTITAHDDRGIRFLDNRTGKSVHSMVAHLDAV 682
           G    T+++          +       PL ++A  D+ I+  DN+T    H+ V H   +
Sbjct: 340 GECKFTVDANSHQDWVTCVKFHQDAKSPLVVSASMDKTIKVWDNQTMTLKHTFVGHKTQI 519

Query: 683 TCLAVDPNGVFLMSGSHDCSLRLWSLDNKTCVQEI 717
             + +     +L SGS D  +  W++ N T + +I
Sbjct: 520 NAIDLALKTYYLASGSKDGIVMTWNIQNGTFLGKI 624

 Score = 46.6 bits (109), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 48/185 (25%), Positives = 79/185 (42%), Gaps = 10/185 (5%)
 Frame = +1

Query: 426 KTWNP----KFTL--RSHYDGIRSLAFHHSQSA--LLTASEDGTLKLWNLQKAVTAKKNA 477
           K WN     KFT+   SH D +  + FH    +  +++AS D T+K+W+ Q  +T K   
Sbjct: 322 KIWNTVGECKFTVDANSHQDWVTCVKFHQDAKSPLVVSASMDKTIKVWDNQ-TMTLK--- 489

Query: 478 ALDVEPIHAFRAHRGPVLAVTMGSNSEYCYSGGADARIHSWKIPDLNMDPYDGYDPSVLS 537
                  H F  H+  + A+ +   + Y  SG  D  + +W I +         D  V +
Sbjct: 490 -------HTFVGHKTQINAIDLALKTYYLASGSKDGIVMTWNIQNGTFLGKIDCDCEVNA 648

Query: 538 HVLEGHGDAVWGLAFSPTSQRLASCSADGTVRIWD-PSSSGPSCLCTFPMDGEH-GIPTS 595
                       + FSP    L   +++G ++IWD P+      +   P+D +H     S
Sbjct: 649 ------------VKFSPNKYWLFVGTSEG-IQIWDLPNQKKIKDIRASPIDAQHKSQKKS 789

Query: 596 VAFTS 600
           +A TS
Sbjct: 790 IACTS 804

 Score = 45.1 bits (105), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 36/148 (24%), Positives = 61/148 (41%), Gaps = 1/148 (0%)
 Frame = +1

Query: 426 KTWN-PKFTLRSHYDGIRSLAFHHSQSALLTASEDGTLKLWNLQKAVTAKKNAALDVEPI 484
           +TW  P+ TL+ H   +  ++       +L++S D TL+LW+++K  T ++         
Sbjct: 82  ETWGGPRRTLQGHSHFVSDVSLSADSRYVLSSSWDATLRLWDIKKGNTTRR--------- 234

Query: 485 HAFRAHRGPVLAVTMGSNSEYCYSGGADARIHSWKIPDLNMDPYDGYDPSVLSHVLEGHG 544
             F +H    LAV    ++    SGG D  +  W          D          ++ H 
Sbjct: 235 --FISHTRDALAVAFSPDNRQIASGGRDKALKIWNTVGECKFTVDANSHQDWVTCVKFHQ 408

Query: 545 DAVWGLAFSPTSQRLASCSADGTVRIWD 572
           DA         S  + S S D T+++WD
Sbjct: 409 DA--------KSPLVVSASMDKTIKVWD 468
>03387
          Length = 1891

 Score = 48.9 bits (115), Expect = 7e-06,   Method: Compositional matrix adjust.
 Identities = 41/160 (25%), Positives = 68/160 (42%), Gaps = 3/160 (1%)
 Frame = +1

Query: 437 HYDGIRSLAFHHSQSALL-TASEDGTLKLWNLQKAVTAKKNAALDVEPIHAFRAHRGPVL 495
           H   +  +A+H    +L  + ++D  L +W+ +   T+K        P H   AH   V 
Sbjct: 508 HTSVVEDVAWHLLHESLFGSVADDQKLMIWDTRSNTTSK--------PSHVVDAHTAEVN 663

Query: 496 AVTMGSNSEYCY-SGGADARIHSWKIPDLNMDPYDGYDPSVLSHVLEGHGDAVWGLAFSP 554
            ++    SE+   +G AD  +  W + +L +            H  E H D ++ + +SP
Sbjct: 664 CLSFNPYSEFILATGSADKTVALWDLRNLKLK----------LHSFESHKDEIFQVQWSP 813

Query: 555 TSQR-LASCSADGTVRIWDPSSSGPSCLCTFPMDGEHGIP 593
            ++  LAS   D  + +WD S  G   L   P D E G P
Sbjct: 814 HNETILASSGTDRRLHVWDLSKIGEEQL---PEDAEDGPP 924

 Score = 40.4 bits (93), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 43/147 (29%), Positives = 69/147 (46%), Gaps = 4/147 (2%)
 Frame = +1

Query: 430 PKFTLRSHYDGIRSLAFHHSQSA-LLTASEDGTLKLWNLQKAVTAKKNAALDVEPIHAFR 488
           P+  L+ H      L+++ + +  LL+AS+D T+ LW++    T +++  +D   I  F 
Sbjct: 337 PELRLKGHQKEGYGLSWNPNLNGHLLSASDDHTICLWDINS--TQRESRVVDAHTI--FT 504

Query: 489 AHRGPVLAVTMGSNSEYCYSGGADARIHSWKIPDLNMDPYD--GYDPSVLSHVLEGHGDA 546
            H   V  V      E  +   AD         D  +  +D      S  SHV++ H   
Sbjct: 505 GHTSVVEDVAWHLLHESLFGSVAD---------DQKLMIWDTRSNTTSKPSHVVDAHTAE 657

Query: 547 VWGLAFSPTSQR-LASCSADGTVRIWD 572
           V  L+F+P S+  LA+ SAD TV +WD
Sbjct: 658 VNCLSFNPYSEFILATGSADKTVALWD 738
>01249
          Length = 1743

 Score = 48.5 bits (114), Expect = 9e-06,   Method: Compositional matrix adjust.
 Identities = 48/194 (24%), Positives = 70/194 (36%), Gaps = 46/194 (23%)
 Frame = -1

Query: 434  LRSHYDGIRSLAFHHSQSALLTASEDGTLKLWNLQKAVTAKKNAALDVEPIHAFRAHRGP 493
            L S ++    + F    S  + A+  G L +W+  + VT     A  ++P     AH  P
Sbjct: 1383 LLSDFNEATKIQFTDDGSQFVVATSSGHLNIWDFARVVTTTSQRARGLKPGRTINAHSEP 1204

Query: 494  V--LAVTMGSNSEYCYSGGADARIHSWKIPD---------------LNMDPYDGYDPSVL 536
            +  L V  G  +    S  +D     W +                 L MD  + +  + L
Sbjct: 1203 ITGLHVGCGGPAARVASSSSDGTCKLWDMLSGALLRTMVYETGVGCLIMDKQEHFLLAGL 1024

Query: 537  SH-----------------------------VLEGHGDAVWGLAFSPTSQRLASCSADGT 567
             +                             VL+GH DAV  LAFS   QRLAS S +G 
Sbjct: 1023 DNGDILCSPLFGQISQSEVFVSKHTTKAGERVLQGHSDAVTCLAFSSDGQRLASGSQNGK 844

Query: 568  VRIWDPSSSGPSCL 581
            V IW+  S   + L
Sbjct: 843  VIIWNMESGDSTSL 802

 Score = 33.1 bits (74), Expect = 0.45,   Method: Compositional matrix adjust.
 Identities = 17/49 (34%), Positives = 29/49 (59%), Gaps = 1/49 (2%)
 Frame = -1

Query: 663 FLDNRTGKSVHSMV-AHLDAVTCLAVDPNGVFLMSGSHDCSLRLWSLDN 710
           F+   T K+   ++  H DAVTCLA   +G  L SGS +  + +W++++
Sbjct: 966 FVSKHTTKAGERVLQGHSDAVTCLAFSSDGQRLASGSQNGKVIIWNMES 820

 Score = 32.7 bits (73), Expect = 0.49,   Method: Compositional matrix adjust.
 Identities = 17/71 (23%), Positives = 34/71 (47%), Gaps = 8/71 (11%)
 Frame = -1

Query: 434 LRSHYDGIRSLAFHHSQSALLTASEDGTLKLWNLQKA------VTAKKNAALDVEPI--H 485
           L+ H D +  LAF      L + S++G + +WN++        ++      + + PI   
Sbjct: 927 LQGHSDAVTCLAFSSDGQRLASGSQNGKVIIWNMESGDSTSLDISGAVGNVMIIPPIVHS 748

Query: 486 AFRAHRGPVLA 496
           +  AH+GP ++
Sbjct: 747 STXAHQGPPIS 715
>01327
          Length = 2215

 Score = 48.1 bits (113), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 28/117 (23%), Positives = 53/117 (45%)
 Frame = +3

Query: 600 STEPAHVVASFRSGDTVLYDLEAGSALLTLESRGSSGPAQINQVVSHPSQPLTITAHDDR 659
           S +P   ++  +    VLYD + G     LE R +    +I +V    S     +A  D+
Sbjct: 66  SIQPGLCLSGSKDKSVVLYDYQNGR----LEDRWTGHDREITKVCYGASCNGMFSASRDK 233

Query: 660 GIRFLDNRTGKSVHSMVAHLDAVTCLAVDPNGVFLMSGSHDCSLRLWSLDNKTCVQE 716
            I+        S+   + H   VT + ++ +   L SGS D ++R+W ++   C+++
Sbjct: 234 TIKMWQRGNSHSIRDFIGHDMVVTAIHLNTDNTLLCSGSRDNTVRIWDVETGACLRQ 404

 Score = 45.4 bits (106), Expect = 8e-05,   Method: Compositional matrix adjust.
 Identities = 46/207 (22%), Positives = 81/207 (39%), Gaps = 6/207 (2%)
 Frame = +3

Query: 528 YDGYDPSVLSHVLEGHGDAVWGLAFSPTSQRLASCSADGTVRIWDPSSSGPSCLCTFPMD 587
           YD Y    L     GH   +  + +  +   + S S D T+++W   +S           
Sbjct: 120 YD-YQNGRLEDRWTGHDREITKVCYGASCNGMFSASRDKTIKMWQRGNSHS----IRDFI 284

Query: 588 GEHGIPTSVAFTSTEPAHVVASFRSGDTVLYDLEAGSALLTLESRGSSGPAQ-INQVVSH 646
           G   + T++   +T+   + +  R     ++D+E G+ L     R ++ P   +  V   
Sbjct: 285 GHDMVVTAIHL-NTDNTLLCSGSRDNTVRIWDVETGACL-----RQNNIPQNLVTDVKWL 446

Query: 647 PSQPLTITAHDDRGIRFLDNRTGKSVHSMVAHLDAVTCLAVDPNGVFLMS-----GSHDC 701
           P   L I A +D+ +R  D+RT   V S            V  +G F ++     G + C
Sbjct: 447 PGSHLIIQAGEDKEVRIYDSRTLGIVRSFTKKQYIQMSCDVTADGQFCLTCSNGFGGNGC 626

Query: 702 SLRLWSLDNKTCVQEITAHRKKHEEAI 728
              LW L + +   E   HR+  E  +
Sbjct: 627 EATLWQLSDGSIQNEFKGHREAIEACL 707

 Score = 34.7 bits (78), Expect = 0.15,   Method: Compositional matrix adjust.
 Identities = 59/287 (20%), Positives = 94/287 (32%), Gaps = 5/287 (1%)
 Frame = +3

Query: 454 LTASEDGTLKLWNLQKAVTAKKNAALDVEPIHAFRAHRGPVLAVTMGSNSEYCYSGGADA 513
           L+ S+D ++ L++ Q      +           +  H   +  V  G++    +S   D 
Sbjct: 87  LSGSKDKSVVLYDYQNGRLEDR-----------WTGHDREITKVCYGASCNGMFSASRDK 233

Query: 514 RIHSWKIPDLNMDPYDGYDPSVLSHVLEGHGDAVWGLAFSPTSQRLASCSADGTVRIWDP 573
            I  W+          G   S+   +  GH   V  +  +  +  L S S D TVRIWD 
Sbjct: 234 TIKMWQ---------RGNSHSIRDFI--GHDMVVTAIHLNTDNTLLCSGSRDNTVRIWDV 380

Query: 574 SSSGPSCLCTFPMDGEHGIPTSVAFTSTEPAHVVASFRSGDTVLYDLEAGSALLTLESRG 633
            +   +CL       ++ IP ++                                     
Sbjct: 381 ETG--ACL------RQNNIPQNL------------------------------------- 425

Query: 634 SSGPAQINQVVSHPSQPLTITAHDDRGIRFLDNRTGKSVHSMVAHLDAVTCLAVDPNGVF 693
                 +  V   P   L I A +D+ +R  D+RT   V S            V  +G F
Sbjct: 426 ------VTDVKWLPGSHLIIQAGEDKEVRIYDSRTLGIVRSFTKKQYIQMSCDVTADGQF 587

Query: 694 LMS-----GSHDCSLRLWSLDNKTCVQEITAHRKKHEEAIHAVACHP 735
            ++     G + C   LW L + +   E   HR    EAI A    P
Sbjct: 588 CLTCSNGFGGNGCEATLWQLSDGSIQNEFKGHR----EAIEACLFLP 716
>17602
          Length = 481

 Score = 47.0 bits (110), Expect = 3e-05,   Method: Composition-based stats.
 Identities = 42/171 (24%), Positives = 73/171 (42%), Gaps = 4/171 (2%)
 Frame = +3

Query: 569 RIWDPSSSGPSCLCTFPMDGEHGIPTSVAFTSTEPAHVVASFRSGDTVLYDLEAGSALLT 628
           RIWD  +    CL T P    H  P +    + + + +V+S   G   ++D  +G  L T
Sbjct: 3   RIWDVKTG--KCLKTLP---AHSDPVTAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLXT 167

Query: 629 LESRGSSGPAQINQVVSHPSQPLTITAHDDRGIRFLDNRTGKSVHSMVAHLDAVTCLAVD 688
           L    +     ++ V   P+    + A  D  ++  D   GK + + V H +   C+  +
Sbjct: 168 LIDDDNP---PVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYVGHRNEKYCIFAN 338

Query: 689 ---PNGVFLMSGSHDCSLRLWS-LDNKTCVQEITAHRKKHEEAIHAVACHP 735
                G +++SGS D  + +W+ LD     +   +HR+       AV C P
Sbjct: 339 FSVTGGKWIVSGSEDNMVYIWNLLDQGDSTEATGSHRRG------AVLCLP 473

 Score = 36.2 bits (82), Expect = 0.045,   Method: Composition-based stats.
 Identities = 27/89 (30%), Positives = 36/89 (40%)
 Frame = +3

Query: 540 LEGHGDAVWGLAFSPTSQRLASCSADGTVRIWDPSSSGPSCLCTFPMDGEHGIPTSVAFT 599
           L  H D V  + F+     + S S DG  RIWD +S    CL T   D     P S    
Sbjct: 42  LPAHSDPVTAVHFNRDGSLIVSSSYDGLCRIWDTASG--QCLXTLIDDDNP--PVSFVKF 209

Query: 600 STEPAHVVASFRSGDTVLYDLEAGSALLT 628
           S    +++A+       L+D   G  L T
Sbjct: 210 SPNGKYILAATLDNTLKLWDYSKGKCLKT 296

 Score = 31.6 bits (70), Expect = 1.2,   Method: Composition-based stats.
 Identities = 23/96 (23%), Positives = 36/96 (37%)
 Frame = +3

Query: 489 AHRGPVLAVTMGSNSEYCYSGGADARIHSWKIPDLNMDPYDGYDPSVLSHVLEGHGDAVW 548
           AH  PV AV    +     S   D     W          D      L  +++     V 
Sbjct: 48  AHSDPVTAVHFNRDGSLIVSSSYDGLCRIW----------DTASGQCLXTLIDDDNPPVS 197

Query: 549 GLAFSPTSQRLASCSADGTVRIWDPSSSGPSCLCTF 584
            + FSP  + + + + D T+++WD S     CL T+
Sbjct: 198 FVKFSPNGKYILAATLDNTLKLWDYSKG--KCLKTY 299
>03156
          Length = 1014

 Score = 44.7 bits (104), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 46/200 (23%), Positives = 79/200 (39%), Gaps = 6/200 (3%)
 Frame = +1

Query: 542 GHGDAVWGLAFSPTSQRLASCSADGTVRIWDPSSSGPSCLCTFPMDGEHGIPTSVAFTST 601
           GH   +  + +  +   + S S D T+++W   +S           G   + T++   +T
Sbjct: 49  GHDREITKVCYGASCNGMFSASRDKTIKMWQRGNSHS----IRDFIGHDMVVTAIHL-NT 213

Query: 602 EPAHVVASFRSGDTVLYDLEAGSALLTLESRGSSGPAQ-INQVVSHPSQPLTITAHDDRG 660
           +   + +  R     ++D+E G+ L     R ++ P   +  V   P   L I A +D+ 
Sbjct: 214 DNTLLCSGSRDNTVRIWDVETGACL-----RQNNIPQNLVTDVKWLPGSHLIIQAGEDKE 378

Query: 661 IRFLDNRTGKSVHSMVAHLDAVTCLAVDPNGVFLMS-----GSHDCSLRLWSLDNKTCVQ 715
           +R  D+RT   V S            V  +G F ++     G + C   LW L + +   
Sbjct: 379 VRIYDSRTLGIVRSFTKKQYIQMSCDVTADGQFCLTCSNGFGGNGCEATLWQLSDGSIQN 558

Query: 716 EITAHRKKHEEAIHAVACHP 735
           E   HR    EAI A    P
Sbjct: 559 EFKGHR----EAIEACLFLP 606

 Score = 40.4 bits (93), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 21/88 (23%), Positives = 41/88 (46%)
 Frame = +1

Query: 629 LESRGSSGPAQINQVVSHPSQPLTITAHDDRGIRFLDNRTGKSVHSMVAHLDAVTCLAVD 688
           LE R +    +I +V    S     +A  D+ I+        S+   + H   VT + ++
Sbjct: 31  LEDRWTGHDREITKVCYGASCNGMFSASRDKTIKMWQRGNSHSIRDFIGHDMVVTAIHLN 210

Query: 689 PNGVFLMSGSHDCSLRLWSLDNKTCVQE 716
            +   L SGS D ++R+W ++   C+++
Sbjct: 211 TDNTLLCSGSRDNTVRIWDVETGACLRQ 294
>00825
          Length = 1821

 Score = 43.9 bits (102), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 63/257 (24%), Positives = 101/257 (39%), Gaps = 6/257 (2%)
 Frame = -2

Query: 459  DGTLKLWNLQKAVTAKKNAALDVEPIHAFRAHRGPVLAVTMGSNSEYCYSGGADARIHSW 518
            DG L  WNL K   A +            +AH G V  +   S+ +Y +S G+D  I  W
Sbjct: 1808 DGELICWNLPKQQMACR-----------VQAHDGIVHGMAAHSSGQYFFSCGSDKTIKQW 1662

Query: 519  KIPDLNMDPYDGYDP----SVLSHVLEGHGDAVWGLAFSPTSQRLASCSADGTVRIWDPS 574
                 ++DP     P    ++L+  +    D  W      TS           V +WD  
Sbjct: 1661 -----SLDPEGTIAPEPVNTLLAKCIYTSLDHHWKDDIFVTS--------GSRVDVWDEK 1521

Query: 575  SSGPSCLCTFPMDGEHGIPTSVAFTSTEPAHVVASFRSGDTVLYDLEAGSALLTLESRGS 634
             S P    ++ ++  H     V F   E   + A+      +LYD+  GSA L    R  
Sbjct: 1520 RSEPMRSFSWGVESVH----HVKFNPVETYLLGAAAHDRSILLYDMR-GSAPL----RKV 1368

Query: 635  SGPAQINQVVSHPSQPLTIT-AHDDRGIRFLDNRT-GKSVHSMVAHLDAVTCLAVDPNGV 692
                + N +  +P +  TIT A++D  +   D R     ++    H  AV  +   P G 
Sbjct: 1367 VMKMRTNALSWNPMEAFTITSANEDGNLYTFDMRKLSMPLNMHRDHTAAVMDVDYCPTGR 1188

Query: 693  FLMSGSHDCSLRLWSLD 709
              +S  +D  +R++ +D
Sbjct: 1187 EFVSAGYDKVIRIFPVD 1137
>30176
          Length = 365

 Score = 42.7 bits (99), Expect = 5e-04,   Method: Composition-based stats.
 Identities = 17/32 (53%), Positives = 20/32 (62%)
 Frame = +2

Query: 540 LEGHGDAVWGLAFSPTSQRLASCSADGTVRIW 571
           L+ H   VW L F  T  RLASCS D T++IW
Sbjct: 8   LKSHTSTVWNLTFDKTGTRLASCSDDKTIKIW 103

 Score = 30.4 bits (67), Expect = 2.7,   Method: Composition-based stats.
 Identities = 12/33 (36%), Positives = 21/33 (63%)
 Frame = +2

Query: 433 TLRSHYDGIRSLAFHHSQSALLTASEDGTLKLW 465
           TL+SH   + +L F  + + L + S+D T+K+W
Sbjct: 5   TLKSHTSTVWNLTFDKTGTRLASCSDDKTIKIW 103
>03395
          Length = 2795

 Score = 42.7 bits (99), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 45/215 (20%), Positives = 82/215 (38%)
 Frame = +2

Query: 494 VLAVTMGSNSEYCYSGGADARIHSWKIPDLNMDPYDGYDPSVLSHVLEGHGDAVWGLAFS 553
           V A+ + S      SGG + ++  W   D+  D   G     L   ++ H   V  +   
Sbjct: 5   VTAIAVTSCGTKLVSGGGEGQVRVW---DIVKDMLTGKTRGDLVANMKEHKGKVTAIQIH 175

Query: 554 PTSQRLASCSADGTVRIWDPSSSGPSCLCTFPMDGEHGIPTSVAFTSTEPAHVVASFRSG 613
              +   S S DG+  IWD  ++  S +          +   V F   +  H++ S    
Sbjct: 176 TNDRCCVSASTDGSTIIWDLITNTRSQIVLANT-----LFKCVCF-GGKDLHILTSGTDH 337

Query: 614 DTVLYDLEAGSALLTLESRGSSGPAQINQVVSHPSQPLTITAHDDRGIRFLDNRTGKSVH 673
               +++  G  L  LE    S    IN +         +T  +D  ++      G+  H
Sbjct: 338 KIGYWEVGDGGLLRELE---GSQTGAINTIDIDRDGQTILTGGEDSLLKLWRYNEGEVTH 508

Query: 674 SMVAHLDAVTCLAVDPNGVFLMSGSHDCSLRLWSL 708
           + + H + +T   + PN  +++SG  D +L +W  
Sbjct: 509 TGIGHSNQITKARICPNRHYIVSGGEDGALHIWKF 613

 Score = 42.4 bits (98), Expect = 8e-04,   Method: Compositional matrix adjust.
 Identities = 27/101 (26%), Positives = 36/101 (35%), Gaps = 3/101 (2%)
 Frame = +2

Query: 436 SHYDGIRSLAFHHSQSALLTASEDGTLKLWNLQKAVTAKKNAALDVEPIHAFRAHRGPVL 495
           S    I ++        +LT  ED  LKLW   +            E  H    H   + 
Sbjct: 392 SQTGAINTIDIDRDGQTILTGGEDSLLKLWRYNEG-----------EVTHTGIGHSNQIT 538

Query: 496 AVTMGSNSEYCYSGGADARIHSWKIPD---LNMDPYDGYDP 533
              +  N  Y  SGG D  +H WK PD   ++  P  G  P
Sbjct: 539 KARICPNRHYIVSGGEDGALHIWKFPDGC*VDCLPRHGISP 661

 Score = 29.3 bits (64), Expect = 5.6,   Method: Compositional matrix adjust.
 Identities = 30/180 (16%), Positives = 60/180 (33%), Gaps = 32/180 (17%)
 Frame = +2

Query: 434 LRSHYDGIRSLAFHHSQSALLTASEDGTLKLWNLQK--------AVTAKKNAALDVEPIH 485
           ++ H   + ++  H +    ++AS DG+  +W+L          A T  K      + +H
Sbjct: 134 MKEHKGKVTAIQIHTNDRCCVSASTDGSTIIWDLITNTRSQIVLANTLFKCVCFGGKDLH 313

Query: 486 AFRA-----------------------HRGPVLAVTMGSNSEYCYSGGADARIHSWKIPD 522
              +                         G +  + +  + +   +GG D+ +  W+   
Sbjct: 314 ILTSGTDHKIGYWEVGDGGLLRELEGSQTGAINTIDIDRDGQTILTGGEDSLLKLWR--- 484

Query: 523 LNMDPYDGYDPSVLSHVLEGHGDAVWGLAFSPTSQRLASCSADGTVRIWD-PSSSGPSCL 581
                   Y+   ++H   GH + +      P    + S   DG + IW  P      CL
Sbjct: 485 --------YNEGEVTHTGIGHSNQITKARICPNRHYIVSGGEDGALHIWKFPDGC*VDCL 640
>02948
          Length = 1207

 Score = 42.7 bits (99), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 25/76 (32%), Positives = 35/76 (46%), Gaps = 2/76 (2%)
 Frame = -2

Query: 638 AQINQVVSHPSQPLTITAHDDRGIRFLDNRTGKSVHSMVAHLDA--VTCLAVDPNGVFLM 695
           A    V  HP+     T H    I F  N         V+H  +  VTCLA  P G  L+
Sbjct: 753 AAFTCVSCHPTDVCIATGHASGKITFWWNFDQDKTVLSVSHWHSLPVTCLAFTPEGSCLL 574

Query: 696 SGSHDCSLRLWSLDNK 711
           SG H+C+L  W ++++
Sbjct: 573 SGGHECTLVRWQMNSE 526
>01462
          Length = 995

 Score = 42.4 bits (98), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 26/83 (31%), Positives = 36/83 (43%)
 Frame = +2

Query: 507 YSGGADARIHSWKIPDLNMDPYDGYDPSVLSHVLEGHGDAVWGLAFSPTSQRLASCSADG 566
           Y+G  D +IH W I           +     + +EGH D +  +     +Q   S S DG
Sbjct: 245 YAGAGDRKIHVWDI-----------EAGQYLNAMEGHKDYIHKVVMKNDAQECVSASEDG 391

Query: 567 TVRIWDPSSSGPSCLCTFPMDGE 589
           TVR+WD  SS  +  C  P   E
Sbjct: 392 TVRMWDIRSSTETVHCLEPSKNE 460

 Score = 29.3 bits (64), Expect = 6.2,   Method: Compositional matrix adjust.
 Identities = 10/37 (27%), Positives = 22/37 (59%)
 Frame = +2

Query: 434 LRSHYDGIRSLAFHHSQSALLTASEDGTLKLWNLQKA 470
           +  H D I  +   +     ++ASEDGT+++W+++ +
Sbjct: 311 MEGHKDYIHKVVMKNDAQECVSASEDGTVRMWDIRSS 421
>13278
          Length = 870

 Score = 42.0 bits (97), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 25/103 (24%), Positives = 50/103 (48%), Gaps = 1/103 (0%)
 Frame = +1

Query: 614 DTVLYDLEAGSALLTLESRGSSGPAQINQVVSHPSQPLTI-TAHDDRGIRFLDNRTGKSV 672
           D+ ++DL+  +  +       +GP       S+P+  L + +A  D  +R  +   G  +
Sbjct: 19  DSCIHDLQLTTKEIYTIKWSPTGPG-----TSNPNTSLILASASFDSTVRLWEVERGLCL 183

Query: 673 HSMVAHLDAVTCLAVDPNGVFLMSGSHDCSLRLWSLDNKTCVQ 715
           H++  H + V  +A  P+G +L SGS D  + +W++   + V 
Sbjct: 184 HTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNVQTGSLVH 312

 Score = 33.5 bits (75), Expect = 0.34,   Method: Compositional matrix adjust.
 Identities = 16/35 (45%), Positives = 21/35 (60%)
 Frame = +1

Query: 538 HVLEGHGDAVWGLAFSPTSQRLASCSADGTVRIWD 572
           H L  H + V+ +AFSP  + LAS S D  V IW+
Sbjct: 184 HTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWN 288
>19140
          Length = 573

 Score = 40.8 bits (94), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 24/84 (28%), Positives = 39/84 (46%), Gaps = 2/84 (2%)
 Frame = -3

Query: 434 LRSHYDGIRSLAFHHSQSALLTASEDGTLKLWNL--QKAVTAKKNAALDVEPIHAFRAHR 491
           L+ H D +++L  +   +  L+ S DGT++LW+L  Q+ V               FR H 
Sbjct: 499 LKGHTDNVKALVLNRDGTQCLSGSSDGTIRLWSLGQQRCVA-------------TFRVHD 359

Query: 492 GPVLAVTMGSNSEYCYSGGADARI 515
             V A+    +    YSGG D ++
Sbjct: 358 EGVWALQANESFTTLYSGGRDHQV 287

 Score = 40.4 bits (93), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 23/68 (33%), Positives = 36/68 (52%)
 Frame = -3

Query: 664 LDNRTGKSVHSMVAHLDAVTCLAVDPNGVFLMSGSHDCSLRLWSLDNKTCVQEITAHRKK 723
           L  RT   +  +  H D V  L ++ +G   +SGS D ++RLWSL  + CV    A  + 
Sbjct: 532 LGPRTCHKLMKLKGHTDNVKALVLNRDGTQCLSGSSDGTIRLWSLGQQRCV----ATFRV 365

Query: 724 HEEAIHAV 731
           H+E + A+
Sbjct: 364 HDEGVWAL 341

 Score = 31.2 bits (69), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 25/94 (26%), Positives = 36/94 (38%)
 Frame = -3

Query: 540 LEGHGDAVWGLAFSPTSQRLASCSADGTVRIWDPSSSGPSCLCTFPMDGEHGIPTSVAFT 599
           L+GH D V  L  +    +  S S+DGT+R+W                            
Sbjct: 499 LKGHTDNVKALVLNRDGTQCLSGSSDGTIRLW---------------------------- 404

Query: 600 STEPAHVVASFRSGDTVLYDLEAGSALLTLESRG 633
           S      VA+FR  D  ++ L+A  +  TL S G
Sbjct: 403 SLGQQRCVATFRVHDEGVWALQANESFTTLYSGG 302
>02090
          Length = 1841

 Score = 40.8 bits (94), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 38/148 (25%), Positives = 59/148 (39%), Gaps = 5/148 (3%)
 Frame = -3

Query: 566  GTVRIWDPSSSGPSCLCTFPMDGEHGIPTSVAFTSTEPAHVVA----SFRSGDTV-LYDL 620
            G V++WD S  G    C       + I  +V  TS   +        S+R   T+ ++DL
Sbjct: 1830 GCVKVWDISQPGTKAPCL------NWIACNVTITSGPSSCCRTGAR*SWREASTLSIWDL 1669

Query: 621  EAGSALLTLESRGSSGPAQINQVVSHPSQPLTITAHDDRGIRFLDNRTGKSVHSMVAHLD 680
               +  +  E   SS PA     +S P   +  +   D  I   D      V     H D
Sbjct: 1668 ATPTPRIKAE-LTSSAPACYALAIS-PDGKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTD 1495

Query: 681  AVTCLAVDPNGVFLMSGSHDCSLRLWSL 708
              +C+ + P+G  L +G  D ++R W L
Sbjct: 1494 GASCIDISPDGTKLWTGGLDNTVRSWDL 1411

 Score = 32.0 bits (71), Expect = 0.99,   Method: Compositional matrix adjust.
 Identities = 26/115 (22%), Positives = 40/115 (34%)
 Frame = -3

Query: 458  EDGTLKLWNLQKAVTAKKNAALDVEPIHAFRAHRGPVLAVTMGSNSEYCYSGGADARIHS 517
            E  TL +W+L       K       P            A+ +  + + C+S  +D  I  
Sbjct: 1698 EASTLSIWDLATPTPRIKAELTSSAP---------ACYALAISPDGKVCFSCCSDGNIAV 1546

Query: 518  WKIPDLNMDPYDGYDPSVLSHVLEGHGDAVWGLAFSPTSQRLASCSADGTVRIWD 572
            W + +             L    +GH D    +  SP   +L +   D TVR WD
Sbjct: 1545 WDLHN-----------QTLVRQFQGHTDGASCIDISPDGTKLWTGGLDNTVRSWD 1414

 Score = 29.3 bits (64), Expect = 5.6,   Method: Compositional matrix adjust.
 Identities = 13/40 (32%), Positives = 21/40 (52%)
 Frame = -3

Query: 681  AVTCLAVDPNGVFLMSGSHDCSLRLWSLDNKTCVQEITAH 720
            A   LA+ P+G    S   D ++ +W L N+T V++   H
Sbjct: 1620 ACYALAISPDGKVCFSCCSDGNIAVWDLHNQTLVRQFQGH 1501
>21921
          Length = 1341

 Score = 40.0 bits (92), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 31/96 (32%), Positives = 45/96 (46%)
 Frame = -1

Query: 533 PSVLSHVLEGHGDAVWGLAFSPTSQRLASCSADGTVRIWDPSSSGPSCLCTFPMDGEHGI 592
           P+  + V +GH   V  +   PT Q L S S DGT+R W+ SS    C+ T  +    G 
Sbjct: 516 PTTQALVYKGHTGIVRSICPDPTGQWLVSGSDDGTIRFWEVSSG--RCMKTLQVG---GC 352

Query: 593 PTSVAFTSTEPAHVVASFRSGDTVLYDLEAGSALLT 628
            TSVA+       VVA+  +   +L +   G  L+ 
Sbjct: 351 VTSVAWNPNPSLCVVAATLNTTVLLINPGLGDKLVV 244

 Score = 34.3 bits (77), Expect = 0.21,   Method: Compositional matrix adjust.
 Identities = 16/55 (29%), Positives = 29/55 (52%), Gaps = 2/55 (3%)
 Frame = -1

Query: 665 DNRTGKSVHSMV--AHLDAVTCLAVDPNGVFLMSGSHDCSLRLWSLDNKTCVQEI 717
           D R   +  ++V   H   V  +  DP G +L+SGS D ++R W + +  C++ +
Sbjct: 531 DLRPFPTTQALVYKGHTGIVRSICPDPTGQWLVSGSDDGTIRFWEVSSGRCMKTL 367
>07741
          Length = 2119

 Score = 39.7 bits (91), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 36/132 (27%), Positives = 60/132 (45%), Gaps = 11/132 (8%)
 Frame = +1

Query: 540 LEGHGDAVWGLAFSPTSQRL-ASCSADGTVRIWD----PSSSGPSCLC-----TFPMDGE 589
           L+ H  AV+ +A++    ++ A+CSAD  V+IW+    P+ +G   L      +F ++  
Sbjct: 229 LDSHNMAVYKVAWNHYHPKIYATCSADWNVKIWENGGKPTDTGXDSLSRKPLFSFDLNNS 408

Query: 590 HGIPTSVAFTSTEPAHVVASFRSGDTVLYDLEAGS-ALLTLESRGSSGPAQINQVVSHPS 648
            G      ++ST  A V A    G   +YDL       L  +        ++  +  +PS
Sbjct: 409 VGDVAWAPYSSTVFAAVTA---DGKVCVYDLSVNKYEPLCEQMVAQKKKTKLTHIEFNPS 579

Query: 649 QPLTITAHDDRG 660
            P+ I   DDRG
Sbjct: 580 YPILIVG-DDRG 612
>15780
          Length = 735

 Score = 38.9 bits (89), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 21/55 (38%), Positives = 27/55 (49%)
 Frame = -1

Query: 654 TAHDDRGIRFLDNRTGKSVHSMVAHLDAVTCLAVDPNGVFLMSGSHDCSLRLWSL 708
           TA  D  +   D  +G +V  + AH D V  L    +G  L SG  D S+RLW L
Sbjct: 723 TAGADHTVIVWDIASGTAVAHLTAHTDTVYALCFSRDGTVLASGGMDNSIRLWDL 559

 Score = 34.7 bits (78), Expect = 0.16,   Method: Compositional matrix adjust.
 Identities = 21/69 (30%), Positives = 31/69 (44%)
 Frame = -1

Query: 504 EYCYSGGADARIHSWKIPDLNMDPYDGYDPSVLSHVLEGHGDAVWGLAFSPTSQRLASCS 563
           +Y  + GAD  +  W I             + ++H L  H D V+ L FS     LAS  
Sbjct: 735 KYLSTAGADHTVIVWDIAS----------GTAVAH-LTAHTDTVYALCFSRDGTVLASGG 589

Query: 564 ADGTVRIWD 572
            D ++R+WD
Sbjct: 588 MDNSIRLWD 562
>18981
          Length = 407

 Score = 38.5 bits (88), Expect = 0.011,   Method: Composition-based stats.
 Identities = 18/51 (35%), Positives = 28/51 (54%)
 Frame = -2

Query: 668 TGKSVHSMVAHLDAVTCLAVDPNGVFLMSGSHDCSLRLWSLDNKTCVQEIT 718
           TG+ VH +  H +A+T +  D      +SGS D  +R W+LD   C+  +T
Sbjct: 211 TGRPVHQLHGHTEAITAVQFDEGKA--VSGSADGDVRTWALDTGQCLLTMT 65
>04358
          Length = 2430

 Score = 38.1 bits (87), Expect = 0.012,   Method: Compositional matrix adjust.
 Identities = 76/297 (25%), Positives = 117/297 (39%), Gaps = 20/297 (6%)
 Frame = +1

Query: 433  TLRSHYDGIRSLAFHHSQSAL-LTASEDGTLKLWNLQKAVTAKKNAALDVEPIHAFRAHR 491
            TL  H D I S+ F H+   L +TAS D T+++W+ + +V+       +V+     +  +
Sbjct: 1405 TLTGHDDVISSIRFLHTDPGLIMTASHDHTVRIWDPRASVSK------EVQRFSGEQNTK 1566

Query: 492  GPVLAVTMGSNSEYCYSG----GADARIHSWKIPDLNMDPYDGYDPSVLSHVLEGHGDAV 547
              VL+  +  +     +G      DA +  W          D     +L    + H D +
Sbjct: 1567 CSVLSCDVNISDRVLCAGTEMSNDDAYLLFW----------DRRKDKLLGCYEDSHHDDI 1716

Query: 548  WGLAFSPTSQR-LASCSADGTVRIWD--PSSSGPSCLCTFPMD------GEHGIPTS--- 595
              + F PTS++ L + S DG V ++D   ++   + + T+  +      G  G P S   
Sbjct: 1717 TQVHFGPTSEKTLLTGSTDGLVNVFDVMQTTEDDALMSTYNTEATVERAGWCG-PQSQQV 1893

Query: 596  VAFTSTEPAHVVASFRSGDT-VLYDLEAG-SALLTLESRGSSGPAQINQVVSHPSQPLTI 653
             A T     HV  + +  D   L DLE         +      PA  NQ  S P      
Sbjct: 1894 YAITHMLSWHVWDTEKDEDVQQLTDLEQKLQGQCQADYLVDCIPA--NQSTSPPCLVAGT 2067

Query: 654  TAHDDRGIRFLDNRTGKSVHSMV-AHLDAVTCLAVDPNGVFLMSGSHDCSLRLWSLD 709
               D   +   D    K V S+   H D V CL  D     L++G  D  L LWS D
Sbjct: 2068 HTGDLHVLDLSDLEEVKVVRSLSGGHTDTVRCLHWDKQTQTLVTGGEDSMLCLWSSD 2238

 Score = 30.4 bits (67), Expect = 2.6,   Method: Compositional matrix adjust.
 Identities = 17/41 (41%), Positives = 23/41 (56%), Gaps = 1/41 (2%)
 Frame = +1

Query: 537  SHVLEGHGDAVWGLAFSPTSQRL-ASCSADGTVRIWDPSSS 576
            ++ L GH D +  + F  T   L  + S D TVRIWDP +S
Sbjct: 1399 TNTLTGHDDVISSIRFLHTDPGLIMTASHDHTVRIWDPRAS 1521
>12574
          Length = 521

 Score = 37.7 bits (86), Expect = 0.018,   Method: Composition-based stats.
 Identities = 36/163 (22%), Positives = 56/163 (34%)
 Frame = +3

Query: 536 LSHVLEGHGDAVWGLAFSPTSQRLASCSADGTVRIWDPSSSGPSCLCTFPMDGEHGIPTS 595
           L   L GH  A+  + FSP    LAS SAD  ++IW               DG+      
Sbjct: 162 LKFTLAGHTKALSAVKFSPNGDWLASSSADKLIKIWG------------AYDGK------ 287

Query: 596 VAFTSTEPAHVVASFRSGDTVLYDLEAGSALLTLESRGSSGPAQINQVVSHPSQPLTITA 655
             F  T   H +                                ++ V       L  +A
Sbjct: 288 --FEKTIAGHKLG-------------------------------LSDVAWSSDSKLLCSA 368

Query: 656 HDDRGIRFLDNRTGKSVHSMVAHLDAVTCLAVDPNGVFLMSGS 698
            DD+ ++  +  TGK + ++  H + V C   +P    ++SGS
Sbjct: 369 SDDKTLKIWEFSTGKCMKTLKGHSNYVFCCNFNPQSNLIVSGS 497

 Score = 35.8 bits (81), Expect = 0.074,   Method: Composition-based stats.
 Identities = 27/88 (30%), Positives = 39/88 (44%), Gaps = 1/88 (1%)
 Frame = +3

Query: 489 AHRGPVLAVTMGSNSEYCYSGGADARIHSWKIPDLNMDPYDG-YDPSVLSHVLEGHGDAV 547
            H   + AV    N ++  S  AD  I  W         YDG ++ ++  H L G  D  
Sbjct: 180 GHTKALSAVKFSPNGDWLASSSADKLIKIW-------GAYDGKFEKTIAGHKL-GLSDVA 335

Query: 548 WGLAFSPTSQRLASCSADGTVRIWDPSS 575
           W    S  S+ L S S D T++IW+ S+
Sbjct: 336 W----SSDSKLLCSASDDKTLKIWEFST 407

 Score = 34.7 bits (78), Expect = 0.14,   Method: Composition-based stats.
 Identities = 31/139 (22%), Positives = 53/139 (38%)
 Frame = +3

Query: 425 KKTWNPKFTLRSHYDGIRSLAFHHSQSALLTASEDGTLKLWNLQKAVTAKKNAALDVEPI 484
           K T+  KFTL  H   + ++ F  +   L ++S D  +K+W            A D +  
Sbjct: 147 KPTYTLKFTLAGHTKALSAVKFSPNGDWLASSSADKLIKIW-----------GAYDGKFE 293

Query: 485 HAFRAHRGPVLAVTMGSNSEYCYSGGADARIHSWKIPDLNMDPYDGYDPSVLSHVLEGHG 544
                H+  +  V   S+S+   S   D  +  W+           +        L+GH 
Sbjct: 294 KTIAGHKLGLSDVAWSSDSKLLCSASDDKTLKIWE-----------FSTGKCMKTLKGHS 440

Query: 545 DAVWGLAFSPTSQRLASCS 563
           + V+   F+P S  + S S
Sbjct: 441 NYVFCCNFNPQSNLIVSGS 497
>01805
          Length = 2124

 Score = 37.0 bits (84), Expect = 0.027,   Method: Compositional matrix adjust.
 Identities = 47/175 (26%), Positives = 81/175 (46%), Gaps = 6/175 (3%)
 Frame = -1

Query: 540 LEGHGDAVWGLAFSPTSQR-LASCSADGTVRIWDPSSSGPSCLCTFPMDGEHG--IPTSV 596
           + GH  AV  L+++  ++  LAS SAD TV +WD S    +   T     +H   +    
Sbjct: 588 VTGHTQAVLDLSWNRNARHVLASASADTTVALWDLSEGKMAMNFT-----QHSREVQCCN 424

Query: 597 AFTSTEPAHVVASFRSGDTVLYDLEAGSALLTLESRGSSGPAQINQVVSHPSQPLTITAH 656
                E   +  SF   D  +  ++  SA    +S    G  ++ + V +   PL + A 
Sbjct: 423 WHPQEEQTLLTGSF---DNTVKVVDCRSAETCHKSWTVEG--EVEKAVWNHHNPLQLLAC 259

Query: 657 DDRGIRF-LDNRTGKSVHSMVAHLDAVT--CLAVDPNGVFLMSGSHDCSLRLWSL 708
            D+G+ +  D R  K V S+ AH   VT  CL+    G+ +++ S D ++++W +
Sbjct: 258 TDKGMVYCFDIRHEKPVFSVGAHSSCVTGVCLSSQIPGL-MITTSEDKTMKVWDI 97
>15118
          Length = 1074

 Score = 37.0 bits (84), Expect = 0.028,   Method: Compositional matrix adjust.
 Identities = 18/69 (26%), Positives = 37/69 (53%)
 Frame = +3

Query: 640 INQVVSHPSQPLTITAHDDRGIRFLDNRTGKSVHSMVAHLDAVTCLAVDPNGVFLMSGSH 699
           I++++ H    +     +D  +  +D  T + V     H +++T L+   +G +L++ S 
Sbjct: 336 ISRILLHRDSNMLAVVLEDFTVSVIDVDTLRVVRVFSGHSNSITDLSFSGDGRWLITASM 515

Query: 700 DCSLRLWSL 708
           DC++R WSL
Sbjct: 516 DCTVRTWSL 542

 Score = 37.0 bits (84), Expect = 0.029,   Method: Compositional matrix adjust.
 Identities = 34/139 (24%), Positives = 53/139 (38%), Gaps = 3/139 (2%)
 Frame = +3

Query: 436 SHYDGIRSLAFHHSQSALLTASEDGTLKLWNL---QKAVTAKKNAALDVEPIHAFRAHRG 492
           +H  G+R +AF      L+TA  D  +K W      +A    K   +  E I     HR 
Sbjct: 186 AHVSGVRGVAFDAFNCLLITAGGDCDIKFWRFGSRDRARVLLKELKMS-EGISRILLHR- 359

Query: 493 PVLAVTMGSNSEYCYSGGADARIHSWKIPDLNMDPYDGYDPSVLSHVLEGHGDAVWGLAF 552
                              D+ + +  + D  +   D  D   +  V  GH +++  L+F
Sbjct: 360 -------------------DSNMLAVVLEDFTVSVID-VDTLRVVRVFSGHSNSITDLSF 479

Query: 553 SPTSQRLASCSADGTVRIW 571
           S   + L + S D TVR W
Sbjct: 480 SGDGRWLITASMDCTVRTW 536
>11493
          Length = 535

 Score = 37.0 bits (84), Expect = 0.031,   Method: Composition-based stats.
 Identities = 31/135 (22%), Positives = 48/135 (35%)
 Frame = -2

Query: 435 RSHYDGIRSLAFHHSQSALLTASEDGTLKLWNLQKAVTAKKNAALDVEPIHAFRAHRGPV 494
           R +Y  IRS+        L+   E   L +W+L       K       P           
Sbjct: 342 RDNY--IRSVKLLPDGRTLIVGGEASNLSIWDLASPTPRIKAELTSAAP---------AC 196

Query: 495 LAVTMGSNSEYCYSGGADARIHSWKIPDLNMDPYDGYDPSVLSHVLEGHGDAVWGLAFSP 554
            A+ +  +S+ C+S  +D  I  W + +            +L    +GH D    +  SP
Sbjct: 195 YALAISPDSKVCFSCCSDGNIAVWDLHN-----------EILVRQFQGHTDGASCIDISP 49

Query: 555 TSQRLASCSADGTVR 569
              RL +   D TVR
Sbjct: 48  DGSRLWTGGLDNTVR 4

 Score = 32.3 bits (72), Expect = 0.67,   Method: Composition-based stats.
 Identities = 34/131 (25%), Positives = 51/131 (38%), Gaps = 41/131 (31%)
 Frame = -2

Query: 483 PIHAFR----AHRGPVLAVTMGSNSEYCYSGGA-------------------------DA 513
           P HA +    +H   V AVT+ + ++Y Y+GG                          D 
Sbjct: 513 PRHARQINTLSHGEVVCAVTISNPTKYVYTGGKGCVKVWDISQPGNKNPVSQLDCLQRDN 334

Query: 514 RIHSWKI-PD----------LNMDPYDGYDPSV-LSHVLEGHGDAVWGLAFSPTSQRLAS 561
            I S K+ PD           N+  +D   P+  +   L     A + LA SP S+   S
Sbjct: 333 YIRSVKLLPDGRTLIVGGEASNLSIWDLASPTPRIKAELTSAAPACYALAISPDSKVCFS 154

Query: 562 CSADGTVRIWD 572
           C +DG + +WD
Sbjct: 153 CCSDGNIAVWD 121

 Score = 29.3 bits (64), Expect = 5.8,   Method: Composition-based stats.
 Identities = 34/163 (20%), Positives = 63/163 (38%), Gaps = 1/163 (0%)
 Frame = -2

Query: 543 HGDAVWGLAFSPTSQRLASCSADGTVRIWDPSSSG-PSCLCTFPMDGEHGIPTSVAFTST 601
           HG+ V  +  S  ++ + +    G V++WD S  G  + +             SV     
Sbjct: 480 HGEVVCAVTISNPTKYVYT-GGKGCVKVWDISQPGNKNPVSQLDCLQRDNYIRSVKLLPD 304

Query: 602 EPAHVVASFRSGDTVLYDLEAGSALLTLESRGSSGPAQINQVVSHPSQPLTITAHDDRGI 661
               +V    + +  ++DL + +  +  E   S+ PA     +S P   +  +   D  I
Sbjct: 303 GRTLIVGG-EASNLSIWDLASPTPRIKAELT-SAAPACYALAIS-PDSKVCFSCCSDGNI 133

Query: 662 RFLDNRTGKSVHSMVAHLDAVTCLAVDPNGVFLMSGSHDCSLR 704
              D      V     H D  +C+ + P+G  L +G  D ++R
Sbjct: 132 AVWDLHNEILVRQFQGHTDGASCIDISPDGSRLWTGGLDNTVR 4
>14555
          Length = 627

 Score = 36.6 bits (83), Expect = 0.043,   Method: Composition-based stats.
 Identities = 16/51 (31%), Positives = 27/51 (52%)
 Frame = -3

Query: 657 DDRGIRFLDNRTGKSVHSMVAHLDAVTCLAVDPNGVFLMSGSHDCSLRLWS 707
           +D  +   D   G     +  H + V+CL + P+G  L +GS D +LR+W+
Sbjct: 406 NDYTVNVWDALKGMRSTILYGHDNRVSCLRISPDGTSLCTGSWDYTLRIWA 254
>21763
          Length = 923

 Score = 36.2 bits (82), Expect = 0.050,   Method: Compositional matrix adjust.
 Identities = 28/105 (26%), Positives = 47/105 (44%)
 Frame = +1

Query: 630 ESRGSSGPAQINQVVSHPSQPLTITAHDDRGIRFLDNRTGKSVHSMVAHLDAVTCLAVDP 689
           +S  S     I  V  HP +P+   A   R +R  +  T + V  +  +   ++ + V P
Sbjct: 298 QSPFSQSKGLIQCVKFHPLRPIFFVA-SQRFVRIYNLLTQQFVKKLQTNCKWISSMDVHP 474

Query: 690 NGVFLMSGSHDCSLRLWSLDNKTCVQEITAHRKKHEEAIHAVACH 734
            G  ++ GS+DC    + LD  T   +I  H   H+ A+  V+ H
Sbjct: 475 GGDNVIIGSYDCKSCWFDLDLSTKPYKILRH---HKRAVRHVSYH 600
>20662
          Length = 1220

 Score = 36.2 bits (82), Expect = 0.051,   Method: Compositional matrix adjust.
 Identities = 38/147 (25%), Positives = 56/147 (38%), Gaps = 5/147 (3%)
 Frame = +2

Query: 440 GIRSLAFHHSQSALLTASEDGTLKLWNLQ---KAVTAKKNAALDVEPIHAFRAHRGPVLA 496
           G+R  A+  S   L+   + G + LW LQ   K  +   +A            H     +
Sbjct: 257 GLRDAAWVDSHKVLV-GLDTGGVALWELQDEDKMFSMLSSAC----------EHDDMTAS 403

Query: 497 VTMGSNSEYCYSGGADARIHSWKIPDLNMDPYDGYDPSVLSHVLEGHGDAVWGLAFSPTS 556
           V++ S+  +  S   D  I  W     ++  Y              H D VW +   PT 
Sbjct: 404 VSINSDXSHYLSASYDHGIKVWNTDLTSLYTY------------RAHSDIVWDVQCHPTE 547

Query: 557 QRL-ASCSADGTVRIWDPSSSGP-SCL 581
             L  SCS DG + +WD   S P +CL
Sbjct: 548 PALFLSCSQDGKIVLWDVRESKPATCL 628
>37180
          Length = 681

 Score = 36.2 bits (82), Expect = 0.055,   Method: Compositional matrix adjust.
 Identities = 24/73 (32%), Positives = 40/73 (54%), Gaps = 1/73 (1%)
 Frame = +1

Query: 639 QINQVVSHPSQPLTITAHDDRGIRFLDNR-TGKSVHSMVAHLDAVTCLAVDPNGVFLMSG 697
           +++ V +HP+Q L +T+  D   R  D R +   V+    H   VT  AV  +G  ++SG
Sbjct: 25  ELSDVHAHPTQRLVVTSSKDMTFRLWDFRDSALLVNVFQGHTQPVTS-AVFASGDKVVSG 201

Query: 698 SHDCSLRLWSLDN 710
           S D ++R+W + N
Sbjct: 202 SDDRTVRVWDMRN 240

 Score = 32.7 bits (73), Expect = 0.52,   Method: Compositional matrix adjust.
 Identities = 17/51 (33%), Positives = 28/51 (54%)
 Frame = +1

Query: 522 DLNMDPYDGYDPSVLSHVLEGHGDAVWGLAFSPTSQRLASCSADGTVRIWD 572
           D+    +D  D ++L +V +GH   V    F+ +  ++ S S D TVR+WD
Sbjct: 82  DMTFRLWDFRDSALLVNVFQGHTQPVTSAVFA-SGDKVVSGSDDRTVRVWD 231
>26939
          Length = 388

 Score = 35.0 bits (79), Expect = 0.097,   Method: Composition-based stats.
 Identities = 13/31 (41%), Positives = 22/31 (70%)
 Frame = +2

Query: 691 GVFLMSGSHDCSLRLWSLDNKTCVQEITAHR 721
           G +L+S S D ++R+W L NK C++ + AH+
Sbjct: 2   GKYLVSASDDKTIRVWDLRNKRCMKTLYAHQ 94

 Score = 33.5 bits (75), Expect = 0.35,   Method: Composition-based stats.
 Identities = 15/54 (27%), Positives = 30/54 (55%)
 Frame = +2

Query: 653 ITAHDDRGIRFLDNRTGKSVHSMVAHLDAVTCLAVDPNGVFLMSGSHDCSLRLW 706
           ++A DD+ IR  D R  + + ++ AH    T +       +++SGS D ++++W
Sbjct: 14  VSASDDKTIRVWDLRNKRCMKTLYAHQHFCTSIDFHKAHPYVISGSVDQTVKVW 175
>26107
          Length = 1338

 Score = 35.0 bits (79), Expect = 0.11,   Method: Compositional matrix adjust.
 Identities = 34/169 (20%), Positives = 67/169 (39%)
 Frame = -3

Query: 538  HVLEGHGDAVWGLAFSPTSQRLASCSADGTVRIWDPSSSGPSCLCTFPMDGEHGIPTSVA 597
            H    H +AV+  ++     +  + S D TV +WD  ++    + TF   G      SVA
Sbjct: 1105 HRWXAHNNAVFDYSWISNDSQCLTASGDQTVALWDVETTTK--VTTFI--GHKCSVRSVA 938

Query: 598  FTSTEPAHVVASFRSGDTVLYDLEAGSALLTLESRGSSGPAQINQVVSHPSQPLTITAHD 657
               + PA   +  R G  +L+D          + R     +Q++QV          + H 
Sbjct: 937  SCPSSPAQCASGARDGHIMLWDSRVN------KKREHQPCSQVHQVCPQ-------SGHQ 797

Query: 658  DRGIRFLDNRTGKSVHSMVAHLDAVTCLAVDPNGVFLMSGSHDCSLRLW 706
             +  +            ++    +VTC+    + + + SG++D  +++W
Sbjct: 796  SKPAKHRRIHRAAGPKGVMDTQQSVTCVLYQTDNLIISSGANDGCVKMW 650

 Score = 29.6 bits (65), Expect = 5.3,   Method: Compositional matrix adjust.
 Identities = 23/84 (27%), Positives = 38/84 (45%), Gaps = 1/84 (1%)
 Frame = -3

Query: 436  SHYDGIRSLAFHHSQSALLTASEDGTLKLWNLQKAVTAKKNAALDVEPIHAFRAHRGPVL 495
            +H + +   ++  + S  LTAS D T+ LW+++   T K         +  F  H+  V 
Sbjct: 1093 AHNNAVFDYSWISNDSQCLTASGDQTVALWDVE--TTTK---------VTTFIGHKCSVR 947

Query: 496  AV-TMGSNSEYCYSGGADARIHSW 518
            +V +  S+   C SG  D  I  W
Sbjct: 946  SVASCPSSPAQCASGARDGHIMLW 875
>04524
          Length = 1340

 Score = 35.0 bits (79), Expect = 0.11,   Method: Compositional matrix adjust.
 Identities = 33/129 (25%), Positives = 55/129 (42%), Gaps = 11/129 (8%)
 Frame = -1

Query: 594  TSVAFTSTEPAHVVASFRSGDTVLYDLEAGSALLTLESRGSSGPAQINQVVSHPSQPL-- 651
            TSV FTS E   V+ + ++GD  +Y     + +   +        Q+  ++ H S  L  
Sbjct: 1172 TSVTFTSDE-GQVIVADKTGD--VYTFPTTTQVEVKDEGEVKTHGQL--LLGHLSMVLDV 1008

Query: 652  --------TITAHDDRGIRFLDNRTGKSVHSM-VAHLDAVTCLAVDPNGVFLMSGSHDCS 702
                     +T   D  IR        ++H+  + H   V CL        L+SGS DC+
Sbjct: 1007 CLTGREGHVVTCDRDEKIRVSQFPNAYNIHTYCLGHTQFVNCLVYVEEFRVLISGSGDCT 828

Query: 703  LRLWSLDNK 711
            +R W+++ K
Sbjct: 827  VRAWNMEGK 801
>31474
          Length = 403

 Score = 34.7 bits (78), Expect = 0.16,   Method: Compositional matrix adjust.
 Identities = 14/42 (33%), Positives = 21/42 (50%)
 Frame = -3

Query: 539 VLEGHGDAVWGLAFSPTSQRLASCSADGTVRIWDPSSSGPSC 580
            L  H +  W +A++PT   LASC +D  ++IW        C
Sbjct: 320 CLSAHDEHAWCVAWNPTGTLLASCGSDKIIKIWGKEGDNWVC 195
>38362
          Length = 1255

 Score = 34.3 bits (77), Expect = 0.17,   Method: Compositional matrix adjust.
 Identities = 18/54 (33%), Positives = 27/54 (50%), Gaps = 1/54 (1%)
 Frame = -1

Query: 539 VLEGHGDAVWGLAFSPTSQRLASCSADGTVRIWDPSSSGP-SCLCTFPMDGEHG 591
           + + H   VW ++++ T   L S  ADG VRIW  +  G  +C+     DG  G
Sbjct: 631 LFDSHDSQVWRVSWNVTGTILVSSGADGCVRIWKANYLGSWACISVLKGDGTPG 470
>12140
          Length = 727

 Score = 34.3 bits (77), Expect = 0.19,   Method: Composition-based stats.
 Identities = 47/172 (27%), Positives = 69/172 (40%), Gaps = 22/172 (12%)
 Frame = +2

Query: 427 TWNPKFTLRSHYDGIRSLAFHHSQSALLTA--SEDGTLKL--------WNLQK---AVTA 473
           +W+  F   +H   + S+ F   +  L+ A  S DG+L +        W+ +K   A T 
Sbjct: 5   SWDKLFEYSNHDSSVNSVCFAPHELGLILACGSSDGSLSIISTTGDGNWDSKKINNAHTI 184

Query: 474 KKNA---ALDVEPIHAF--RAHRGPVLAVTMGSNSEYCYSGGADARIHSWKIPDLNMDPY 528
             NA   A    P   F   A + PV         +   SGG D  +  W+      +  
Sbjct: 185 GCNAVSWAPSTAPNALFDQSARQQPV---------KRFVSGGCDNLVKIWR------EDE 319

Query: 529 DGYDPSVLSHVLEGHGDAVWGLAFSPT----SQRLASCSADGTVRIWDPSSS 576
            G+   V    LEGH D V  +A++P+       +ASCS D  V IW    S
Sbjct: 320 TGW---VEDQKLEGHSDWVRDVAWAPSIGLPRNVIASCSQDCRVIIWTNDGS 466
>12960
          Length = 550

 Score = 34.3 bits (77), Expect = 0.21,   Method: Compositional matrix adjust.
 Identities = 39/154 (25%), Positives = 55/154 (35%), Gaps = 9/154 (5%)
 Frame = +2

Query: 431 KFTLRSHYDGIRSLAFHHSQSALLTASEDGTLKLWNLQKAVTAKKNAALDVEPIHAFRAH 490
           + T+      +R++ F       +T   D ++KLWN  + +  K            +  H
Sbjct: 152 EVTINCKQQAVRAVRFSVDSRYCMTCGSDKSVKLWNPHRELFLK-----------TYIGH 298

Query: 491 RGPVL-AVTMGSNSEYCYSGGADARIHSWKIPDLNMDPYDGYDPSVLSHVLEG------- 542
              VL A   G NS+ C SGG D  +                   VL  V  G       
Sbjct: 299 GHEVLDAQGSGDNSQIC-SGGIDKTV-------------------VLFDVASGQALRKYR 418

Query: 543 -HGDAVWGLAFSPTSQRLASCSADGTVRIWDPSS 575
            H   V  + F+  S  + S S D TVR WD  S
Sbjct: 419 DHAGTVNCVKFNEESTVILSGSLDNTVRAWDTRS 520

 Score = 30.0 bits (66), Expect = 3.8,   Method: Compositional matrix adjust.
 Identities = 32/161 (19%), Positives = 57/161 (35%)
 Frame = +2

Query: 546 AVWGLAFSPTSQRLASCSADGTVRIWDPSSSGPSCLCTFPMDGEHGIPTSVAFTSTEPAH 605
           AV  + FS  S+   +C +D +V++W+P                        F  T   H
Sbjct: 179 AVRAVRFSVDSRYCMTCGSDKSVKLWNPHRE--------------------LFLKTYIGH 298

Query: 606 VVASFRSGDTVLYDLEAGSALLTLESRGSSGPAQINQVVSHPSQPLTITAHDDRGIRFLD 665
                  G  VL            +++GS   +QI             +   D+ +   D
Sbjct: 299 -------GHEVL------------DAQGSGDNSQI------------CSGGIDKTVVLFD 385

Query: 666 NRTGKSVHSMVAHLDAVTCLAVDPNGVFLMSGSHDCSLRLW 706
             +G+++     H   V C+  +     ++SGS D ++R W
Sbjct: 386 VASGQALRKYRDHAGTVNCVKFNEESTVILSGSLDNTVRAW 508
>15337
          Length = 860

 Score = 34.3 bits (77), Expect = 0.22,   Method: Compositional matrix adjust.
 Identities = 18/101 (17%), Positives = 41/101 (40%)
 Frame = -1

Query: 632 RGSSGPAQINQVVSHPSQPLTITAHDDRGIRFLDNRTGKSVHSMVAHLDAVTCLAVDPNG 691
           R   G   I++    P          D  +R  +  + + + +M ++   + C+   P+G
Sbjct: 344 RWVVGTGAISEFAFSPCSRYLAVVGQDGHLRVFNYNSMELIGTMKSYFGGLLCVCWSPDG 165

Query: 692 VFLMSGSHDCSLRLWSLDNKTCVQEITAHRKKHEEAIHAVA 732
            ++++G  D  + +WS   K     +      H+  ++ VA
Sbjct: 164 KYIVTGGEDDLVTVWSFHEK----RVVCRGHGHKSWVNVVA 54
>30295
          Length = 593

 Score = 33.5 bits (75), Expect = 0.32,   Method: Composition-based stats.
 Identities = 36/142 (25%), Positives = 56/142 (39%), Gaps = 2/142 (1%)
 Frame = +2

Query: 433 TLRSHYDGIRSLAFHHSQSALLTASEDGTLKLWNLQKAVTAKKNAALDVEPIHAFRAHRG 492
           TLR H   I ++ +      L++AS+DG L +W+     T  K        +HA      
Sbjct: 230 TLRXHLAKIYAMHWATDSRNLVSASQDGKLIVWD---GYTTNK--------VHAIPLRSS 376

Query: 493 PVLAVTMGSNSEYCYSGGAD--ARIHSWKIPDLNMDPYDGYDPSVLSHVLEGHGDAVWGL 550
            V+      +  Y   GG D    I+S K  + N+          +S  L GH   +   
Sbjct: 377 WVMTCAYAPSGGYVACGGLDNICSIYSLKTREGNVR---------VSRELPGHTGYLSCC 529

Query: 551 AFSPTSQRLASCSADGTVRIWD 572
            F   +Q + + S D T  +WD
Sbjct: 530 RFIDDNQ-IVTSSGDMTCALWD 592
>19863
          Length = 502

 Score = 33.5 bits (75), Expect = 0.35,   Method: Composition-based stats.
 Identities = 23/69 (33%), Positives = 29/69 (42%)
 Frame = +1

Query: 508 SGGADARIHSWKIPDLNMDPYDGYDPSVLSHVLEGHGDAVWGLAFSPTSQRLASCSADGT 567
           SG +D  I  W + +            V    L+GH   V  + FS     L SCS D T
Sbjct: 22  SGSSDMSIVVWDVEN-----------GVQKLRLQGHAGWVNDVHFSQDQCWLLSCSNDNT 168

Query: 568 VRIWDPSSS 576
           VRIW+   S
Sbjct: 169 VRIWNIEES 195
>38039
          Length = 816

 Score = 33.1 bits (74), Expect = 0.45,   Method: Compositional matrix adjust.
 Identities = 18/61 (29%), Positives = 28/61 (45%)
 Frame = -1

Query: 541 EGHGDAVWGLAFSPTSQRLASCSADGTVRIWDPSSSGPSCLCTFPMDGEHGIPTSVAFTS 600
           + H D + GL      +  AS S DGT+R+W+  +     L        + IP S+ F S
Sbjct: 516 DDHVDLITGLTSCSRMKLFASSSMDGTIRVWNEENRLVRVLRL------NAIPNSIGFCS 355

Query: 601 T 601
           +
Sbjct: 354 S 352
>08679
          Length = 2028

 Score = 33.1 bits (74), Expect = 0.48,   Method: Compositional matrix adjust.
 Identities = 25/77 (32%), Positives = 40/77 (51%), Gaps = 1/77 (1%)
 Frame = -3

Query: 501  SNSEYCYSGGADARIHSWKIPDLNMDPYDGYDPSVLSHVLEGHGDAVWGLAFSP-TSQRL 559
            +N  +  + G+D +   W +  L+     G +P  L  ++  HG  V    FSP T  R+
Sbjct: 1510 TNPHFFVTAGSDMKXSVWDLRKLSAS--KGNEP--LHSMM--HGKTVSSAYFSPLTGARI 1349

Query: 560  ASCSADGTVRIWDPSSS 576
             SCSAD T+ +++ SSS
Sbjct: 1348 LSCSADDTLNVFNCSSS 1298
>16199
          Length = 694

 Score = 32.7 bits (73), Expect = 0.56,   Method: Composition-based stats.
 Identities = 11/41 (26%), Positives = 21/41 (51%)
 Frame = +2

Query: 681 AVTCLAVDPNGVFLMSGSHDCSLRLWSLDNKTCVQEITAHR 721
           A+TC    P+G+   +G+ D  +++W L  +  V     H+
Sbjct: 77  ALTCAQFHPDGLIFATGTEDSVIKIWDLKERANVANFQGHQ 199

 Score = 30.0 bits (66), Expect = 3.8,   Method: Composition-based stats.
 Identities = 15/53 (28%), Positives = 27/53 (50%)
 Frame = +2

Query: 446 FHHSQSALLTASEDGTLKLWNLQKAVTAKKNAALDVEPIHAFRAHRGPVLAVT 498
           FH       T +ED  +K+W+L++    + N A        F+ H+GPV +++
Sbjct: 95  FHPDGLIFATGTEDSVIKIWDLKE----RANVA-------NFQGHQGPVTSIS 220
>02960
          Length = 1577

 Score = 32.7 bits (73), Expect = 0.60,   Method: Compositional matrix adjust.
 Identities = 25/94 (26%), Positives = 40/94 (42%), Gaps = 7/94 (7%)
 Frame = +2

Query: 623 GSALLTLESRGSSGPAQINQVVSHPSQP----LTITAHDDRGIRFLDNRTGKSVH---SM 675
           G A++T+   G + P +    + H            +HD   + +   R    V    S 
Sbjct: 572 GEAIMTIP--GHTSPVKCVAWIKHDESSGVSTFVTGSHDQTALVWQWQRETNEVDCRLSC 745

Query: 676 VAHLDAVTCLAVDPNGVFLMSGSHDCSLRLWSLD 709
             H  +V C+AV P+   + +GS D  L+LWS D
Sbjct: 746 RGHAASVDCVAVSPDSQQMCTGSWDKMLKLWSTD 847
>25930
          Length = 419

 Score = 32.3 bits (72), Expect = 0.64,   Method: Compositional matrix adjust.
 Identities = 14/41 (34%), Positives = 26/41 (63%)
 Frame = +1

Query: 439 DGIRSLAFHHSQSALLTASEDGTLKLWNLQKAVTAKKNAAL 479
           D I++L +    + L++ SE GTL++W+L+     K++A L
Sbjct: 199 DSIKNLNWSLDATRLISVSESGTLQVWDLEGPAVNKQDARL 321
>10264
          Length = 416

 Score = 32.3 bits (72), Expect = 0.67,   Method: Compositional matrix adjust.
 Identities = 17/74 (22%), Positives = 33/74 (44%), Gaps = 1/74 (1%)
 Frame = -1

Query: 448 HSQSALLTASEDGTLKLWNLQKAVTAKKNAALDVEPIHAFRAHRGPVLAVTM-GSNSEYC 506
           H  + L++   D    +W++QK     +           F+ H G +L     G + +  
Sbjct: 212 HHDARLVSVGYDAEAFVWDVQKGTALAQ-----------FKGHMGRLLTCQFSGLDPDLV 66

Query: 507 YSGGADARIHSWKI 520
            +GG+DA +H W++
Sbjct: 65  MTGGSDASVHVWRV 24
>27681
          Length = 465

 Score = 32.3 bits (72), Expect = 0.82,   Method: Compositional matrix adjust.
 Identities = 14/29 (48%), Positives = 20/29 (68%)
 Frame = +2

Query: 551 AFSPTSQRLASCSADGTVRIWDPSSSGPS 579
           A++PT+  LAS S D T RIW+ +S  P+
Sbjct: 14  AWNPTNDLLASGSGDSTARIWNMTSETPN 100
>30297
          Length = 822

 Score = 32.0 bits (71), Expect = 0.96,   Method: Compositional matrix adjust.
 Identities = 11/38 (28%), Positives = 24/38 (63%)
 Frame = -1

Query: 672 VHSMVAHLDAVTCLAVDPNGVFLMSGSHDCSLRLWSLD 709
           + S   H+++V+CL +      L++ + DC++R+W+ D
Sbjct: 249 IQSWRGHVESVSCLDLVEQNKVLLTSAADCTVRMWTTD 136
>06576
          Length = 1547

 Score = 32.0 bits (71), Expect = 1.00,   Method: Compositional matrix adjust.
 Identities = 24/73 (32%), Positives = 33/73 (45%), Gaps = 1/73 (1%)
 Frame = -2

Query: 537  SHVLEGHGDAVWGLAFSPTSQ-RLASCSADGTVRIWDPSSSGPSCLCTFPMDGEHGIPTS 595
            +HV++GH D V  + FSPT + ++ S   D T R+W               DG +G   S
Sbjct: 1105 THVVKGHTDFVNSVTFSPTEEDQVXSTGDDLTCRVWTGKDG---------QDGRYG--ES 959

Query: 596  VAFTSTEPAHVVA 608
            V F  T P   V 
Sbjct: 958  VIFRLTAPGMAVC 920
>11915
          Length = 737

 Score = 31.6 bits (70), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 28/83 (33%), Positives = 40/83 (48%), Gaps = 3/83 (3%)
 Frame = +1

Query: 654 TAHDDRGIRFLDNRTGKSVHSMVAHLDAVTCL--AVDPNGVFLMSGSHDCSLRLWSLDNK 711
           T H    I+  +  TGK +  M+ H   V  L  A D N + LMS SHD +++LW  D++
Sbjct: 457 TGHVSGRIKLWNCETGKLLIEMMDHKATVHDLHFAAD-NSLCLMSASHDGTVKLWEFDDQ 633

Query: 712 -TCVQEITAHRKKHEEAIHAVAC 733
             C   +T        A HA +C
Sbjct: 634 GDCNMYLTL----RTNAKHAFSC 690
>16360
          Length = 1148

 Score = 31.6 bits (70), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 19/60 (31%), Positives = 30/60 (50%)
 Frame = -1

Query: 657 DDRGIRFLDNRTGKSVHSMVAHLDAVTCLAVDPNGVFLMSGSHDCSLRLWSLDNKTCVQE 716
           +D+G R    RT  S+HS++       CL    N +   + S  C LRL++L   +C Q+
Sbjct: 551 EDKGQRL*QERTVLSIHSLML------CLQSLNNSMIESTFSKPCRLRLFTLFQVSCKQQ 390
>34511
          Length = 1037

 Score = 31.6 bits (70), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 13/33 (39%), Positives = 21/33 (63%)
 Frame = +3

Query: 675 MVAHLDAVTCLAVDPNGVFLMSGSHDCSLRLWS 707
           +  H + V+CL V  NG+ + +GS D  LR+W+
Sbjct: 60  LAGHDNRVSCLGVTENGMSVATGSWDSFLRVWN 158
>34005
          Length = 456

 Score = 31.6 bits (70), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 18/87 (20%), Positives = 39/87 (44%), Gaps = 6/87 (6%)
 Frame = +1

Query: 637 PAQINQVVSHPSQPLTITAHDDRGIRFLDNRTGKSV---HSMVAHLDAVTCLAVDPNGVF 693
           P ++  +   P      +  +D  +   D+  G  V   H++ +H  AV  +A  P    
Sbjct: 112 PQEVCGLSWSPDATFLASGSNDNSVNIWDSTLGMDVPPLHTLTSHQAAVKAVAWCPWQTR 291

Query: 694 LMS---GSHDCSLRLWSLDNKTCVQEI 717
           +++   G++D  +R W+ +   CV+ +
Sbjct: 292 MLATGGGTNDRHIRFWNTNTGACVKAV 372
>03044
          Length = 1952

 Score = 30.0 bits (66), Expect = 3.2,   Method: Compositional matrix adjust.
 Identities = 11/29 (37%), Positives = 17/29 (58%)
 Frame = -2

Query: 543  HGDAVWGLAFSPTSQRLASCSADGTVRIW 571
            HG  V G+ ++P S R+ +C AD    +W
Sbjct: 1657 HGQRVTGIDWAPKSNRIVTCGADRNAYVW 1571
>12841
          Length = 1364

 Score = 29.3 bits (64), Expect = 5.6,   Method: Compositional matrix adjust.
 Identities = 14/38 (36%), Positives = 21/38 (55%), Gaps = 1/38 (2%)
 Frame = +1

Query: 542  GHGDAVWGLAFSP-TSQRLASCSADGTVRIWDPSSSGP 578
            GH   V+ + +SP  S    SCSAD ++R+W    + P
Sbjct: 1042 GHTAPVYHIRWSPFVSDIFLSCSADWSIRLWHQDRTTP 1155
>15745
          Length = 1183

 Score = 29.3 bits (64), Expect = 6.0,   Method: Compositional matrix adjust.
 Identities = 25/73 (34%), Positives = 36/73 (49%), Gaps = 9/73 (12%)
 Frame = +2

Query: 537 SHVLEG-HGDAVWGLAFSPTSQR-LASCSADGTVRIWDPSSSGPSCLCTFPM----DGEH 590
           ++ +EG HG  V  L F+P  Q  LASC  D  V+ WD  +      C+ P+    D  H
Sbjct: 686 TYQMEGAHGQLVRDLDFNPNRQYYLASCGDDCRVKFWDTRN------CSEPLKVLSDHSH 847

Query: 591 ---GIPTSVAFTS 600
              G  T+++ TS
Sbjct: 848 WVWGCGTTISMTS 886
>01768
          Length = 1424

 Score = 28.9 bits (63), Expect = 7.8,   Method: Compositional matrix adjust.
 Identities = 14/32 (43%), Positives = 20/32 (62%), Gaps = 1/32 (3%)
 Frame = +3

Query: 542 GHGDAVWGLAFSPTSQRL-ASCSADGTVRIWD 572
            H D+V  + +SP    + ASCS D T+RIW+
Sbjct: 831 AHTDSVEDVQWSPNEGNVFASCSVDRTLRIWN 926
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|110625942|ref|NP_082583.1| tudor and KH domain
containing protein [Mus musculus]
         (560 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

04982                                                                 160   1e-39
02407                                                                  69   7e-12
06128                                                                  60   3e-09
34863                                                                  54   1e-07
21795                                                                  47   2e-05
36453                                                                  45   8e-05
11318                                                                  45   1e-04
03467                                                                  44   2e-04
03574                                                                  41   0.001
32342                                                                  38   0.010
18876                                                                  35   0.10 
34552                                                                  34   0.14 
05451                                                                  34   0.19 
31560                                                                  31   1.3  
00601                                                                  31   1.7  
06127                                                                  30   2.9  
>04982
          Length = 1215

 Score =  160 bits (405), Expect = 1e-39,   Method: Compositional matrix adjust.
 Identities = 83/193 (43%), Positives = 119/193 (61%), Gaps = 6/193 (3%)
 Frame = +1

Query: 306 EYLEVYVSASEHPNHFWIQIIGSRSLQLDKLVSEMTQHYEN---SLPEDLT-VHVGDIVA 361
           E++EV+VSA EH  HFW+Q++ + +L LDK+  +M+  Y N   +    LT V  GD+VA
Sbjct: 241 EFMEVFVSAVEHAGHFWLQMVNTTALNLDKMTDDMSLFYSNPDTAQTYRLTEVKEGDVVA 420

Query: 362 APLSTNGSWYRARVLGTLENGNLDLYFVDFGDNGDCALKDLRALRSDFLSLPFQAIECSL 421
           A  + +  WYRARV+G  E+G +DLY+ DFGDNG    + LR L++++LSLP QAIEC L
Sbjct: 421 AAFAEDNMWYRARVVG-FEDGKVDLYYFDFGDNGLVPEEALRELKAEYLSLPVQAIECKL 597

Query: 422 ARIAPTGXXX-XXXALDEFDRLTHCADWKPLVAKISSYVQTGISTWPKIYLYD-TSDEKK 479
           A + P G       + D F+ LTHCA+WK L A+   YV       P + L D  +  + 
Sbjct: 598 ANVKPVGGERWSDESSDMFEELTHCAEWKILSARTVGYVPVEWGQCPCVQLVDNNAXPQP 777

Query: 480 LDIGLELVRKGYA 492
           LD+ +E+V +G A
Sbjct: 778 LDVAVEMVSRGVA 816
>02407
          Length = 2662

 Score = 68.6 bits (166), Expect = 7e-12,   Method: Compositional matrix adjust.
 Identities = 61/216 (28%), Positives = 103/216 (47%), Gaps = 2/216 (0%)
 Frame = -2

Query: 307  YLEVYVSASEHPNHFWIQIIGSRSLQLDKLVSEMTQHYENS--LPEDLTVHVGDIVAAPL 364
            Y +V ++       F+ Q + +   Q+++L+ +M Q  +++  LP   T   GD+ AA  
Sbjct: 2658 YTKVIITEVTDDFTFYAQKVDN-GPQVERLMEQMRQEMDSNPPLPGAYTPKRGDLCAAKF 2482

Query: 365  STNGSWYRARVLGTLENGNLDLYFVDFGDNGDCALKDLRALRSDFLSLPFQAIECSLARI 424
            S +  WYRA+V   + +G  D+ F+DFG+    A   L AL + FLS P QA E SLA +
Sbjct: 2481 SADDQWYRAKV-QKVHSGKADILFIDFGNKESVASGSLAALPAAFLSTPPQANEYSLAGV 2305

Query: 425  APTGXXXXXXALDEFDRLTHCADWKPLVAKISSYVQTGISTWPKIYLYDTSDEKKLDIGL 484
            A           D  D L    D      +++   ++G   +  +    T ++   D+GL
Sbjct: 2304 ALPPDVVEDGKQDAVDALYR--DIMNHQVQVNVEYRSGGVDYVTMM---TEEDGTGDVGL 2140

Query: 485  ELVRKGYAVELPEDMEENRTVPNMLKDMATETDDSL 520
             L+  GY   L E+ +E R +  ++ D     D++L
Sbjct: 2139 ALINDGYV--LVEERKERR-LAKLMADYKNALDEAL 2041
>06128
          Length = 1202

 Score = 60.1 bits (144), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 39/117 (33%), Positives = 62/117 (52%), Gaps = 2/117 (1%)
 Frame = +3

Query: 307 YLEVYVSASEHPNHFWIQIIGSRSLQLDKLVSEMTQHYENS--LPEDLTVHVGDIVAAPL 364
           Y +V ++       F+ Q + +   Q+++L+ +M Q  +++  LP   T   GD+ AA  
Sbjct: 786 YTKVIITEVTDDFTFYAQKVDN-GPQVERLMEQMRQEMDSNPPLPGAYTPKRGDLCAAKF 962

Query: 365 STNGSWYRARVLGTLENGNLDLYFVDFGDNGDCALKDLRALRSDFLSLPFQAIECSL 421
           S +  WYRA+V   + +G  D+ F+DFG+    A   L AL + FLS P QA E  L
Sbjct: 963 SADDQWYRAKV-QKVHSGKADILFIDFGNKESVASGSLAALPAAFLSTPPQANEYVL 1130
>34863
          Length = 634

 Score = 53.9 bits (128), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 27/71 (38%), Positives = 37/71 (52%), Gaps = 1/71 (1%)
 Frame = -3

Query: 353 TVHVGDIVAAPLSTNGSWYRARVLGTLENGN-LDLYFVDFGDNGDCALKDLRALRSDFLS 411
           TV  GD+V    S +  WYR RV    E+G    ++F D+G+  D  +  L  +   F +
Sbjct: 281 TVSPGDVVLVEFSEDNLWYRGRVERVYEDGTTCSIFFTDYGNKEDKEISSLMVVPQQFRA 102

Query: 412 LPFQAIECSLA 422
           LP QAI C LA
Sbjct: 101 LPAQAIACQLA 69
>21795
          Length = 605

 Score = 46.6 bits (109), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 45/165 (27%), Positives = 73/165 (44%), Gaps = 18/165 (10%)
 Frame = +3

Query: 282 SGAQSSPETSMFEIPSPDFSFHADEYLEVYVSASEHPNHFWIQIIGSRSL-QLDKLVSEM 340
           +GA +S       +P P  S      LE+ V+      HF+ Q +   ++  L  L+S +
Sbjct: 51  AGAGNSAANMRVALPDPTKSV-----LEMQVTEVVQCGHFYAQCMDHENITHLQTLLSML 215

Query: 341 TQHYE----NSLPEDLTVHVGDIVAAP-LSTNGSWYRARVLGTLENGNL----------- 384
               +    N+ P     H   +  AP +    ++YRAR+  +L+   L           
Sbjct: 216 NPCNKLSXLNTPP-----HKDMMCXAPYMDEYEAYYRARI-ESLQTRTLLLRGIPTTTRV 377

Query: 385 -DLYFVDFGDNGDCALKDLRALRSDFLSLPFQAIECSLARIAPTG 428
             ++FVD+G+  +  L  LRAL S+  S+  QAIEC L  I P+ 
Sbjct: 378 AQVFFVDYGNRDEIPLDRLRALPSEAFSISMQAIECELTEIRPSS 512
>36453
          Length = 667

 Score = 45.1 bits (105), Expect = 8e-05,   Method: Compositional matrix adjust.
 Identities = 21/49 (42%), Positives = 30/49 (61%)
 Frame = +3

Query: 378 TLENGNLDLYFVDFGDNGDCALKDLRALRSDFLSLPFQAIECSLARIAP 426
           TL   ++ L     G     +L+ L+ +RSDF++LPFQA+EC LA I P
Sbjct: 171 TLLTTSVRLGTWTMGGYETVSLQTLKQIRSDFMTLPFQAVECYLANITP 317

 Score = 30.4 bits (67), Expect = 2.1,   Method: Compositional matrix adjust.
 Identities = 23/68 (33%), Positives = 35/68 (51%), Gaps = 3/68 (4%)
 Frame = +2

Query: 333 LDKLVSEMTQHYEN-SLPE-DLTVHVGDIVAAPLSTNGSWYRARVLG-TLENGNLDLYFV 389
           L++L   M   Y N S+P   L V  G I AA   + G WYRA+V+     +   ++ ++
Sbjct: 32  LERLNHIMNLCYSNPSVPTLPLPVEGGVICAA--ESEGQWYRAQVMQVNPADDQCEIRYL 205

Query: 390 DFGDNGDC 397
           D+G   DC
Sbjct: 206 DYGGVRDC 229
>11318
          Length = 478

 Score = 44.7 bits (104), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 22/57 (38%), Positives = 32/57 (56%), Gaps = 1/57 (1%)
 Frame = +3

Query: 437 DEFDRLTHCADWKPLVAKISSYVQTGISTWPKIYLYD-TSDEKKLDIGLELVRKGYA 492
           D F+ LTHCA+WK L A+   YV       P + L D  +  + LD+ +E+V +G A
Sbjct: 21  DMFEELTHCAEWKILSARTVGYVPVEWGQCPCVQLVDNNAAPQPLDVAVEMVSRGVA 191
>03467
          Length = 2192

 Score = 43.5 bits (101), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 31/86 (36%), Positives = 46/86 (53%), Gaps = 1/86 (1%)
 Frame = -2

Query: 50   EDDIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGD-ERVLLISGFPVQV 108
            ED++  EM V       IIGR G  I++L+ ++  +I V+ +D  D  R + +SG    +
Sbjct: 2071 EDNLTAEMFVQARDCGKIIGRGGNKIRELQIESRCQIKVNRDDEPDGTRRVDLSGSDDAI 1892

Query: 109  CKAKAAIHQILTENTPVFEQLSVPQR 134
             KAK  IHQ+L E+     Q S  QR
Sbjct: 1891 AKAKDMIHQVLEEDDRGPRQQSYQQR 1814
>03574
          Length = 3150

 Score = 41.2 bits (95), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 24/75 (32%), Positives = 36/75 (48%)
 Frame = -3

Query: 352  LTVHVGDIVAAPLSTNGSWYRARVLGTLENGNLDLYFVDFGDNGDCALKDLRALRSDFLS 411
            L V VG I  A  S + +WYRARVL   +  ++ + +VDFG++       +R +      
Sbjct: 1468 LKVKVGQICLAHFSIDNAWYRARVLEVTQK-DVKVKYVDFGNSSRVDTSLVRRISPQLCD 1292

Query: 412  LPFQAIECSLARIAP 426
             P  A E  L  + P
Sbjct: 1291 KPQIAYEFKLHNLKP 1247

 Score = 35.8 bits (81), Expect = 0.052,   Method: Compositional matrix adjust.
 Identities = 40/152 (26%), Positives = 63/152 (41%), Gaps = 13/152 (8%)
 Frame = -3

Query: 290  TSMFEIPSPDFSFHADEYLEVY---VSASEHPNHFWIQIIG----SRSLQLDKL-VSEMT 341
            TS+ +  +P F     +  +++   V+  E PN  +IQ       + SL  D L   +M 
Sbjct: 1021 TSILKCSNPYFPLRPGQPGDIFTGLVTHVELPNLVYIQRCAAAPDTTSLPEDVLKFVQMM 842

Query: 342  QHYENSLPEDLTVH----VGDIVAAPLSTNGSWYRARVLGTLENGNLDL-YFVDFGDNGD 396
                 S  +D  +      G++ AA  S +   YRA V     +    L Y+VD+G++  
Sbjct: 841  DDLNASPGQDSALQELPAAGEMCAARFSQDDRLYRALVAKNYPHDQTTLVYYVDYGNSEV 662

Query: 397  CALKDLRALRSDFLSLPFQAIECSLARIAPTG 428
              L  L AL   F   P QA+   +    P G
Sbjct: 661  VTLDRLLALPQKFQDTPAQALRAFINLDLPEG 566

 Score = 35.4 bits (80), Expect = 0.065,   Method: Compositional matrix adjust.
 Identities = 30/96 (31%), Positives = 38/96 (39%), Gaps = 1/96 (1%)
 Frame = -2

Query: 332  QLDKLVSEMTQHYENSLPEDLTVHVGDIVAAPLST-NGSWYRARVLGTLENGNLDLYFVD 390
            QL  L+SE+   YE        V  G     P  T +  WYRA +   L +    +  VD
Sbjct: 2474 QLLGLMSELAM-YEVEAVSGPGVEGGSGTVWPKYTKDDRWYRATITAVLHDAVYQVSLVD 2298

Query: 391  FGDNGDCALKDLRALRSDFLSLPFQAIECSLARIAP 426
            FG         LR L+    SL   A  C LA + P
Sbjct: 2297 FGHADTVPSSRLRXLKKSDGSLGXFAERCHLASLCP 2190
>32342
          Length = 661

 Score = 38.1 bits (87), Expect = 0.010,   Method: Compositional matrix adjust.
 Identities = 20/54 (37%), Positives = 36/54 (66%), Gaps = 2/54 (3%)
 Frame = -1

Query: 45  LTFVGEDDIEI--EMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGDE 96
           +   G DD+ +  E+ VP+E++  IIG+ G N+K++++ +GA + V  ED GD+
Sbjct: 643 MRLSGSDDVHLRTEVVVPKESIGRIIGKGGQNVKEMQRVSGAIVQV-PEDQGDQ 485
>18876
          Length = 587

 Score = 34.7 bits (78), Expect = 0.10,   Method: Compositional matrix adjust.
 Identities = 24/75 (32%), Positives = 40/75 (53%), Gaps = 4/75 (5%)
 Frame = +2

Query: 55  IEMRVPQEAVKLIIGRQGANIKQLRKQTGARI----DVDTEDVGDERVLLISGFPVQVCK 110
           +EM +P   V LIIG+ G  I+QL+++ G ++    D +     D + L ISG   +  +
Sbjct: 74  VEMSIPGPKVGLIIGKGGETIRQLQERAGVKMVMIQDSNAPSAAD-KPLRISGDAPKCQR 250

Query: 111 AKAAIHQILTENTPV 125
           AK  + ++L E   V
Sbjct: 251 AKEMVIELLQEKADV 295
>34552
          Length = 564

 Score = 34.3 bits (77), Expect = 0.14,   Method: Compositional matrix adjust.
 Identities = 19/40 (47%), Positives = 22/40 (55%)
 Frame = +2

Query: 49  GEDDIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDV 88
           GE D EI M V Q     IIGR G  +K   ++TGA I V
Sbjct: 371 GEFDCEIRMIVHQSQAGCIIGRAGFKVKD*ERKTGAGIKV 490

 Score = 30.4 bits (67), Expect = 1.9,   Method: Compositional matrix adjust.
 Identities = 18/50 (36%), Positives = 28/50 (56%)
 Frame = +2

Query: 53  IEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGDERVLLIS 102
           +EI + +  +    IIG+ G NIK+LR    A + V  +  G ER+L +S
Sbjct: 152 VEIRVLLQSKNAGAIIGKGGTNIKRLRTDFKASVTV-PDSSGPERILTVS 298
>05451
          Length = 769

 Score = 33.9 bits (76), Expect = 0.19,   Method: Compositional matrix adjust.
 Identities = 14/44 (31%), Positives = 26/44 (59%)
 Frame = +2

Query: 370 WYRARVLGTLENGNLDLYFVDFGDNGDCALKDLRALRSDFLSLP 413
           +YRA ++  L+ G  +++F+DFG+N         A+ ++F  LP
Sbjct: 11  FYRAEIVKLLDEGKCEVHFIDFGNN---------AITNEFRQLP 115
>31560
          Length = 597

 Score = 31.2 bits (69), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 13/22 (59%), Positives = 18/22 (81%)
 Frame = -3

Query: 67 IIGRQGANIKQLRKQTGARIDV 88
          IIG+ GANIK++R +T  RID+
Sbjct: 85 IIGKGGANIKKIRDETNTRIDL 20

 Score = 29.3 bits (64), Expect = 4.6,   Method: Compositional matrix adjust.
 Identities = 20/52 (38%), Positives = 28/52 (53%), Gaps = 2/52 (3%)
 Frame = -1

Query: 56  EMRVPQEAVKLIIGRQGANIKQLRKQTG--ARIDVDTEDVGDERVLLISGFP 105
           E+ V  +  K IIG+ GANI +++   G   RI  DTE   +  V+ I G P
Sbjct: 555 EIEVDPKFHKHIIGKNGANITRIKDDNGVSVRIPSDTE---NSNVIRIEGDP 409
>00601
          Length = 1129

 Score = 30.8 bits (68), Expect = 1.7,   Method: Compositional matrix adjust.
 Identities = 17/41 (41%), Positives = 21/41 (51%)
 Frame = +3

Query: 283  GAQSSPETSMFEIPSPDFSFHADEYLEVYVSASEHPNHFWI 323
            GA +SP T  F+  S  F F     LEVY+S     +HF I
Sbjct: 1002 GAYNSPHTPFFQYSSXLFCFDYSHILEVYLSIMNFYSHFKI 1124
>06127
          Length = 1172

 Score = 29.6 bits (65), Expect = 2.9,   Method: Compositional matrix adjust.
 Identities = 17/48 (35%), Positives = 22/48 (45%), Gaps = 7/48 (14%)
 Frame = +1

Query: 463 ISTWPKIYLYDTSDEK-------KLDIGLELVRKGYAVELPEDMEENR 503
           I  WPK+ L   S E        KLD+  ++VR+GY   L  D    R
Sbjct: 145 IHNWPKLCLLAMSGETCVGAIVCKLDMHKKMVRRGYIAMLAVDQHHRR 288
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|124107596|ref|NP_058061.2| AMP-activated protein
kinase, noncatalytic gamma-1 subunit [Mus musculus]
         (330 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

26161                                                                 159   1e-39
33158                                                                  30   1.6  
02773                                                                  28   3.5  
>26161
          Length = 423

 Score =  159 bits (403), Expect = 1e-39,   Method: Compositional matrix adjust.
 Identities = 77/141 (54%), Positives = 106/141 (75%), Gaps = 2/141 (1%)
 Frame = -1

Query: 173 KFLKLFITEFPKPEFMSKSLQELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDE 232
           +FL +++ + PKP FMSK+++EL IGT+ ++  V    P+  AL +FV HR+SALPV+D+
Sbjct: 423 RFLHIYLRDLPKPAFMSKTIKELAIGTFNDVITVSKHMPLIQALNLFVDHRISALPVLDD 244

Query: 233 KGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRS--HYFEGVLKCYLHETLETIINR 290
           +G V DIY+KFDVINLAAEKTYNNLD+SV +AL+HRS  + +EGV  C   + LE ++  
Sbjct: 243 EGVVCDIYAKFDVINLAAEKTYNNLDISVEQALRHRSGGNNYEGVATCQEEDRLEDVMET 64

Query: 291 LVEAEVHRLVVVDEHDVVKGI 311
           +V+AEVHRLV VD +  VKGI
Sbjct: 63  IVKAEVHRLVAVDGNRQVKGI 1
>33158
          Length = 1075

 Score = 29.6 bits (65), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 15/33 (45%), Positives = 18/33 (54%)
 Frame = -2

Query: 154 VIDPESGNTLYILTHKRILKFLKLFITEFPKPE 186
           V DPE G+ L  L H  IL+ LKLF      P+
Sbjct: 381 VDDPEGGHGLLSLRHAAILQCLKLFRPSQRSPQ 283
>02773
          Length = 472

 Score = 28.5 bits (62), Expect = 3.5,   Method: Compositional matrix adjust.
 Identities = 15/45 (33%), Positives = 22/45 (48%), Gaps = 7/45 (15%)
 Frame = -3

Query: 98  YKSALVQIYELEEHKIETWREVYLQDS-------FKPLVCISPNA 135
           YK  L+Q  EL   +I  W  +Y   +       F PL+C+ PN+
Sbjct: 458 YKQLLMQCSELLLTEISKWVLIYWSSTY*KGEITFSPLLCMFPNS 324
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|160707911|ref|NP_112435.2| ankyrin 1, erythroid
isoform 2 [Mus musculus]
         (1848 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

19166                                                                 162   1e-39
09292                                                                 149   7e-36
06253                                                                 134   5e-31
11295                                                                 119   1e-26
14005                                                                 108   2e-23
13462                                                                 107   3e-23
02114                                                                  96   1e-19
05924                                                                  94   3e-19
08473                                                                  75   3e-13
25470                                                                  72   1e-12
00540                                                                  72   3e-12
02055                                                                  70   6e-12
21532                                                                  66   2e-10
20792                                                                  65   2e-10
20884                                                                  53   2e-10
15772                                                                  62   2e-09
28494                                                                  62   3e-09
38834                                                                  60   7e-09
12417                                                                  60   8e-09
20036                                                                  59   1e-08
11861                                                                  59   2e-08
09180                                                                  56   1e-07
28113                                                                  55   2e-07
34789                                                                  54   7e-07
16561                                                                  52   2e-06
22305                                                                  50   6e-06
15359                                                                  50   1e-05
35952                                                                  50   1e-05
30463                                                                  49   1e-05
28691                                                                  49   2e-05
33144                                                                  47   5e-05
27108                                                                  46   1e-04
27067                                                                  46   1e-04
03590                                                                  45   2e-04
21751                                                                  45   2e-04
30978                                                                  42   0.002
17893                                                                  41   0.005
25464                                                                  40   0.006
13900                                                                  40   0.007
30217                                                                  39   0.015
08755                                                                  39   0.017
20121                                                                  37   0.055
22269                                                                  37   0.061
05396                                                                  37   0.068
04513                                                                  37   0.069
28671                                                                  37   0.074
18216                                                                  37   0.099
02351                                                                  37   0.10 
35959                                                                  35   0.21 
36917                                                                  33   1.2  
20955                                                                  32   2.9  
18403                                                                  32   3.0  
>19166
          Length = 447

 Score =  162 bits (410), Expect = 1e-39,   Method: Compositional matrix adjust.
 Identities = 83/149 (55%), Positives = 103/149 (69%)
 Frame = +1

Query: 356 RVAKVLLDKGAKPNSRALNGFTPLHIACKKNHIRVMELLLKTGASIDAVTESGLTPLHVA 415
           + AK+LLD+  +PNSRALNGFTPLHIACKKN I+V+ELLLK GASIDA TESGLTPLHV+
Sbjct: 1   KTAKLLLDRKCEPNSRALNGFTPLHIACKKNRIKVVELLLKYGASIDATTESGLTPLHVS 180

Query: 416 SFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVXXXXXXXXXXXXXXXXXXX 475
           SFMGH+ IV  L+Q  A P+   V+ ET LH+AARA  T++                   
Sbjct: 181 SFMGHMNIVIYLIQHNAYPDTPTVRGETSLHLAARANQTDIIRILLRNGAAVDARAREQQ 360

Query: 476 TPLHCAARIGHTGMVKLLLENGASPNLAT 504
           TPLH A+R+G+   V LLL++GAS +  T
Sbjct: 361 TPLHIASRLGNVDNVVLLLQHGASADATT 447

 Score =  119 bits (298), Expect = 1e-26,   Method: Compositional matrix adjust.
 Identities = 63/146 (43%), Positives = 88/146 (60%)
 Frame = +1

Query: 590 KLLLPRGGSPHSPAWNGYTPLHIAAKQNQIEVARSLLQYGGSANAESVQGVTPLHLAAQE 649
           KLLL R   P+S A NG+TPLHIA K+N+I+V   LL+YG S +A +  G+TPLH+++  
Sbjct: 10  KLLLDRKCEPNSRALNGFTPLHIACKKNRIKVVELLLKYGASIDATTESGLTPLHVSSFM 189

Query: 650 GHTEMVALLLSKQANGNLGNKSGLTPLHLVSQEGHVPVADVLIKHGVTVDATTRMGYTPL 709
           GH  +V  L+   A  +     G T LHL ++     +  +L+++G  VDA  R   TPL
Sbjct: 190 GHMNIVIYLIQHNAYPDTPTVRGETSLHLAARANQTDIIRILLRNGAAVDARAREQQTPL 369

Query: 710 HVASHYGNIKLVKFLLQHQADVNAKT 735
           H+AS  GN+  V  LLQH A  +A T
Sbjct: 370 HIASRLGNVDNVVLLLQHGASADATT 447

 Score =  105 bits (262), Expect = 2e-22,   Method: Compositional matrix adjust.
 Identities = 54/148 (36%), Positives = 88/148 (59%)
 Frame = +1

Query: 290 RISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYNAEIDDITLDHLTPLHVA 349
           + +++LLD      ++  NG +P+H+A + + +  V LLL+Y A ID  T   LTPLHV+
Sbjct: 1   KTAKLLLDRKCEPNSRALNGFTPLHIACKKNRIKVVELLLKYGASIDATTESGLTPLHVS 180

Query: 350 AHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHIRVMELLLKTGASIDAVTESGL 409
           +  GH  +   L+   A P++  + G T LH+A + N   ++ +LL+ GA++DA      
Sbjct: 181 SFMGHMNIVIYLIQHNAYPDTPTVRGETSLHLAARANQTDIIRILLRNGAAVDARAREQQ 360

Query: 410 TPLHVASFMGHLPIVKNLLQRGASPNVS 437
           TPLH+AS +G++  V  LLQ GAS + +
Sbjct: 361 TPLHIASRLGNVDNVVLLLQHGASADAT 444

 Score =  103 bits (258), Expect = 5e-22,   Method: Compositional matrix adjust.
 Identities = 54/145 (37%), Positives = 89/145 (61%)
 Frame = +1

Query: 522 TALALLEKEASQACMTKKGFTPLHVAAKYGKVRLAELLLEHDAHPNAAGKNGLTPLHVAV 581
           TA  LL+++         GFTPLH+A K  ++++ ELLL++ A  +A  ++GLTPLHV+ 
Sbjct: 4   TAKLLLDRKCEPNSRALNGFTPLHIACKKNRIKVVELLLKYGASIDATTESGLTPLHVSS 183

Query: 582 HHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQIEVARSLLQYGGSANAESVQGVT 641
              +++IV  L+     P +P   G T LH+AA+ NQ ++ R LL+ G + +A + +  T
Sbjct: 184 FMGHMNIVIYLIQHNAYPDTPTVRGETSLHLAARANQTDIIRILLRNGAAVDARAREQQT 363

Query: 642 PLHLAAQEGHTEMVALLLSKQANGN 666
           PLH+A++ G+ + V LLL   A+ +
Sbjct: 364 PLHIASRLGNVDNVVLLLQHGASAD 438

 Score =  103 bits (257), Expect = 7e-22,   Method: Compositional matrix adjust.
 Identities = 57/146 (39%), Positives = 90/146 (61%)
 Frame = +1

Query: 260 RLLLDRGAQIETRTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQG 319
           +LLLDR  +  +R  +  TPLH A +   +++ E+LL +GA I A T++GL+P+H+++  
Sbjct: 10  KLLLDRKCEPNSRALNGFTPLHIACKKNRIKVVELLLKYGASIDATTESGLTPLHVSSFM 189

Query: 320 DHLDCVRLLLQYNAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPL 379
            H++ V  L+Q+NA  D  T+   T LH+AA      + ++LL  GA  ++RA    TPL
Sbjct: 190 GHMNIVIYLIQHNAYPDTPTVRGETSLHLAARANQTDIIRILLRNGAAVDARAREQQTPL 369

Query: 380 HIACKKNHIRVMELLLKTGASIDAVT 405
           HIA +  ++  + LLL+ GAS DA T
Sbjct: 370 HIASRLGNVDNVVLLLQHGASADATT 447

 Score =  102 bits (255), Expect = 1e-21,   Method: Compositional matrix adjust.
 Identities = 52/128 (40%), Positives = 81/128 (63%)
 Frame = +1

Query: 657 LLLSKQANGNLGNKSGLTPLHLVSQEGHVPVADVLIKHGVTVDATTRMGYTPLHVASHYG 716
           LLL ++   N    +G TPLH+  ++  + V ++L+K+G ++DATT  G TPLHV+S  G
Sbjct: 13  LLLDRKCEPNSRALNGFTPLHIACKKNRIKVVELLLKYGASIDATTESGLTPLHVSSFMG 192

Query: 717 NIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGASPNEVSSNGTTPLA 776
           ++ +V +L+QH A  +  T  G + LH AA+   TDI+ +LL+NGA+ +  +    TPL 
Sbjct: 193 HMNIVIYLIQHNAYPDTPTVRGETSLHLAARANQTDIIRILLRNGAAVDARAREQQTPLH 372

Query: 777 IAKRLGYI 784
           IA RLG +
Sbjct: 373 IASRLGNV 396

 Score =  100 bits (250), Expect = 4e-21,   Method: Compositional matrix adjust.
 Identities = 53/149 (35%), Positives = 87/149 (58%)
 Frame = +1

Query: 554 RLAELLLEHDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIA 613
           + A+LLL+    PN+   NG TPLH+A   N + +V+LLL  G S  +   +G TPLH++
Sbjct: 1   KTAKLLLDRKCEPNSRALNGFTPLHIACKKNRIKVVELLLKYGASIDATTESGLTPLHVS 180

Query: 614 AKQNQIEVARSLLQYGGSANAESVQGVTPLHLAAQEGHTEMVALLLSKQANGNLGNKSGL 673
           +    + +   L+Q+    +  +V+G T LHLAA+   T+++ +LL   A  +   +   
Sbjct: 181 SFMGHMNIVIYLIQHNAYPDTPTVRGETSLHLAARANQTDIIRILLRNGAAVDARAREQQ 360

Query: 674 TPLHLVSQEGHVPVADVLIKHGVTVDATT 702
           TPLH+ S+ G+V    +L++HG + DATT
Sbjct: 361 TPLHIASRLGNVDNVVLLLQHGASADATT 447

 Score = 99.4 bits (246), Expect = 1e-20,   Method: Compositional matrix adjust.
 Identities = 58/149 (38%), Positives = 88/149 (59%)
 Frame = +1

Query: 191 RTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIA 250
           +TA +LL     P+  +  GFTPLHIA     + V +LLL  GAS++ T ++G+TPLH++
Sbjct: 1   KTAKLLLDRKCEPNSRALNGFTPLHIACKKNRIKVVELLLKYGASIDATTESGLTPLHVS 180

Query: 251 SRRGNVIMVRLLLDRGAQIETRTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGL 310
           S  G++ +V  L+   A  +T T    T LH AAR     I  ILL +GA + A+ +   
Sbjct: 181 SFMGHMNIVIYLIQHNAYPDTPTVRGETSLHLAARANQTDIIRILLRNGAAVDARAREQQ 360

Query: 311 SPIHMAAQGDHLDCVRLLLQYNAEIDDIT 339
           +P+H+A++  ++D V LLLQ+ A  D  T
Sbjct: 361 TPLHIASRLGNVDNVVLLLQHGASADATT 447

 Score = 95.9 bits (237), Expect = 1e-19,   Method: Compositional matrix adjust.
 Identities = 53/146 (36%), Positives = 81/146 (55%)
 Frame = +1

Query: 491 KLLLENGASPNLATTAGHTPLHTAAREGHVDTALALLEKEASQACMTKKGFTPLHVAAKY 550
           KLLL+    PN     G TPLH A ++  +     LL+  AS    T+ G TPLHV++  
Sbjct: 10  KLLLDRKCEPNSRALNGFTPLHIACKKNRIKVVELLLKYGASIDATTESGLTPLHVSSFM 189

Query: 551 GKVRLAELLLEHDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPL 610
           G + +   L++H+A+P+     G T LH+A   N  DI+++LL  G +  + A    TPL
Sbjct: 190 GHMNIVIYLIQHNAYPDTPTVRGETSLHLAARANQTDIIRILLRNGAAVDARAREQQTPL 369

Query: 611 HIAAKQNQIEVARSLLQYGGSANAES 636
           HIA++   ++    LLQ+G SA+A +
Sbjct: 370 HIASRLGNVDNVVLLLQHGASADATT 447

 Score = 95.1 bits (235), Expect = 2e-19,   Method: Compositional matrix adjust.
 Identities = 54/145 (37%), Positives = 82/145 (56%)
 Frame = +1

Query: 226 AQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETRTKDELTPLHCAAR 285
           A+LLL+R    N    NG TPLHIA ++  + +V LLL  GA I+  T+  LTPLH ++ 
Sbjct: 7   AKLLLDRKCEPNSRALNGFTPLHIACKKNRIKVVELLLKYGASIDATTESGLTPLHVSSF 186

Query: 286 NGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYNAEIDDITLDHLTP 345
            GH+ I   L+ H A     T  G + +H+AA+ +  D +R+LL+  A +D    +  TP
Sbjct: 187 MGHMNIVIYLIQHNAYPDTPTVRGETSLHLAARANQTDIIRILLRNGAAVDARAREQQTP 366

Query: 346 LHVAAHCGHHRVAKVLLDKGAKPNS 370
           LH+A+  G+     +LL  GA  ++
Sbjct: 367 LHIASRLGNVDNVVLLLQHGASADA 441

 Score = 94.7 bits (234), Expect = 3e-19,   Method: Compositional matrix adjust.
 Identities = 59/165 (35%), Positives = 87/165 (52%)
 Frame = +1

Query: 109 NAQSQKGFTPLYMAAQENHLEVVKFLLENGANQNVATEDGFTPLAVALQQGHENVVAHLI 168
           N+++  GFTPL++A ++N ++VV+ LL+ GA+ +  TE G TPL V+   GH N+V +LI
Sbjct: 40  NSRALNGFTPLHIACKKNRIKVVELLLKYGASIDATTESGLTPLHVSSFMGHMNIVIYLI 219

Query: 169 NYGTKGKVRLPALHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQL 228
                                        Q++  PD  +  G T LH+AA     ++ ++
Sbjct: 220 -----------------------------QHNAYPDTPTVRGETSLHLAARANQTDIIRI 312

Query: 229 LLNRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETRT 273
           LL  GA+V+   +   TPLHIASR GNV  V LLL  GA  +  T
Sbjct: 313 LLRNGAAVDARAREQQTPLHIASRLGNVDNVVLLLQHGASADATT 447

 Score = 94.0 bits (232), Expect = 5e-19,   Method: Compositional matrix adjust.
 Identities = 53/149 (35%), Positives = 88/149 (59%)
 Frame = +1

Query: 620 EVARSLLQYGGSANAESVQGVTPLHLAAQEGHTEMVALLLSKQANGNLGNKSGLTPLHLV 679
           + A+ LL      N+ ++ G TPLH+A ++   ++V LLL   A+ +   +SGLTPLH+ 
Sbjct: 1   KTAKLLLDRKCEPNSRALNGFTPLHIACKKNRIKVVELLLKYGASIDATTESGLTPLHVS 180

Query: 680 SQEGHVPVADVLIKHGVTVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGY 739
           S  GH+ +   LI+H    D  T  G T LH+A+      +++ LL++ A V+A+ +   
Sbjct: 181 SFMGHMNIVIYLIQHNAYPDTPTVRGETSLHLAARANQTDIIRILLRNGAAVDARAREQQ 360

Query: 740 SPLHQAAQQGHTDIVTLLLKNGASPNEVS 768
           +PLH A++ G+ D V LLL++GAS +  +
Sbjct: 361 TPLHIASRLGNVDNVVLLLQHGASADATT 447

 Score = 79.0 bits (193), Expect = 2e-14,   Method: Compositional matrix adjust.
 Identities = 42/126 (33%), Positives = 72/126 (57%)
 Frame = +1

Query: 181 LHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFTP 240
           LHIA + +  +   +LL+   + D  +++G TPLH+++   ++N+   L+   A  +   
Sbjct: 70  LHIACKKNRIKVVELLLKYGASIDATTESGLTPLHVSSFMGHMNIVIYLIQHNAYPDTPT 249

Query: 241 QNGITPLHIASRRGNVIMVRLLLDRGAQIETRTKDELTPLHCAARNGHVRISEILLDHGA 300
             G T LH+A+R     ++R+LL  GA ++ R +++ TPLH A+R G+V    +LL HGA
Sbjct: 250 VRGETSLHLAARANQTDIIRILLRNGAAVDARAREQQTPLHIASRLGNVDNVVLLLQHGA 429

Query: 301 PIQAKT 306
              A T
Sbjct: 430 SADATT 447

 Score = 77.4 bits (189), Expect = 5e-14,   Method: Compositional matrix adjust.
 Identities = 46/123 (37%), Positives = 70/123 (56%)
 Frame = +1

Query: 476 TPLHCAARIGHTGMVKLLLENGASPNLATTAGHTPLHTAAREGHVDTALALLEKEASQAC 535
           TPLH A +     +V+LLL+ GAS +  T +G TPLH ++  GH++  + L++  A    
Sbjct: 64  TPLHIACKKNRIKVVELLLKYGASIDATTESGLTPLHVSSFMGHMNIVIYLIQHNAYPDT 243

Query: 536 MTKKGFTPLHVAAKYGKVRLAELLLEHDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPR 595
            T +G T LH+AA+  +  +  +LL + A  +A  +   TPLH+A    N+D V LLL  
Sbjct: 244 PTVRGETSLHLAARANQTDIIRILLRNGAAVDARAREQQTPLHIASRLGNVDNVVLLLQH 423

Query: 596 GGS 598
           G S
Sbjct: 424 GAS 432

 Score = 73.9 bits (180), Expect = 6e-13,   Method: Compositional matrix adjust.
 Identities = 38/110 (34%), Positives = 72/110 (65%)
 Frame = +1

Query: 36  LRNGVDINTCNQNGLNGLHLASKEGHVKMVVELLHKEIILETTTKKGNTALHIAALAGQD 95
           L+ G  I+   ++GL  LH++S  GH+ +V+ L+      +T T +G T+LH+AA A Q 
Sbjct: 118 LKYGASIDATTESGLTPLHVSSFMGHMNIVIYLIQHNAYPDTPTVRGETSLHLAARANQT 297

Query: 96  EVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQNVAT 145
           +++R L+  GA V+A++++  TPL++A++  +++ V  LL++GA+ +  T
Sbjct: 298 DIIRILLRNGAAVDARAREQQTPLHIASRLGNVDNVVLLLQHGASADATT 447

 Score = 71.2 bits (173), Expect = 4e-12,   Method: Compositional matrix adjust.
 Identities = 48/158 (30%), Positives = 78/158 (49%)
 Frame = +1

Query: 82  GNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQ 141
           G T LHIA    + +VV  L+ YGA+++A ++ G TPL++++   H+ +V +L+++ A  
Sbjct: 58  GFTPLHIACKKNRIKVVELLLKYGASIDATTESGLTPLHVSSFMGHMNIVIYLIQHNAYP 237

Query: 142 NVATEDGFTPLAVALQQGHENVVAHLINYGTKGKVRLPALHIAARNDDTRTAAVLLQNDP 201
           +  T  G T                             +LH+AAR + T    +LL+N  
Sbjct: 238 DTPTVRGET-----------------------------SLHLAARANQTDIIRILLRNGA 330

Query: 202 NPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFT 239
             D  ++   TPLHIA+   N++   LLL  GAS + T
Sbjct: 331 AVDARAREQQTPLHIASRLGNVDNVVLLLQHGASADAT 444

 Score = 70.5 bits (171), Expect = 6e-12,   Method: Compositional matrix adjust.
 Identities = 39/124 (31%), Positives = 70/124 (56%)
 Frame = +1

Query: 48  NGLNGLHLASKEGHVKMVVELLHKEIILETTTKKGNTALHIAALAGQDEVVRELVNYGAN 107
           NG   LH+A K+  +K+V  LL     ++ TT+ G T LH+++  G   +V  L+ + A 
Sbjct: 55  NGFTPLHIACKKNRIKVVELLLKYGASIDATTESGLTPLHVSSFMGHMNIVIYLIQHNAY 234

Query: 108 VNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQNVATEDGFTPLAVALQQGHENVVAHL 167
            +  + +G T L++AA+ N  ++++ LL NGA  +    +  TPL +A + G+ + V  L
Sbjct: 235 PDTPTVRGETSLHLAARANQTDIIRILLRNGAAVDARAREQQTPLHIASRLGNVDNVVLL 414

Query: 168 INYG 171
           + +G
Sbjct: 415 LQHG 426

 Score = 65.5 bits (158), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 32/89 (35%), Positives = 56/89 (62%)
 Frame = +1

Query: 705 GYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGASP 764
           G+TPLH+A     IK+V+ LL++ A ++A T+ G +PLH ++  GH +IV  L+++ A P
Sbjct: 58  GFTPLHIACKKNRIKVVELLLKYGASIDATTESGLTPLHVSSFMGHMNIVIYLIQHNAYP 237

Query: 765 NEVSSNGTTPLAIAKRLGYISVTDVLKVV 793
           +  +  G T L +A R      TD+++++
Sbjct: 238 DTPTVRGETSLHLAARANQ---TDIIRIL 315

 Score = 50.4 bits (119), Expect = 6e-06,   Method: Compositional matrix adjust.
 Identities = 24/72 (33%), Positives = 43/72 (59%)
 Frame = +1

Query: 719 KLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGASPNEVSSNGTTPLAIA 778
           K  K LL  + + N++   G++PLH A ++    +V LLLK GAS +  + +G TPL ++
Sbjct: 1   KTAKLLLDRKCEPNSRALNGFTPLHIACKKNRIKVVELLLKYGASIDATTESGLTPLHVS 180

Query: 779 KRLGYISVTDVL 790
             +G++++   L
Sbjct: 181 SFMGHMNIVIYL 216
>09292
          Length = 1486

 Score =  149 bits (377), Expect = 7e-36,   Method: Compositional matrix adjust.
 Identities = 118/401 (29%), Positives = 185/401 (46%), Gaps = 2/401 (0%)
 Frame = -2

Query: 211  FTPLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIE 270
            F  LH A   +++      L+ G  V+    +  T LH     G+V M  +LL   A + 
Sbjct: 1458 FCALHCAXQLQDVETLLAYLDIGMHVDTRDSHHETALHAVCYVGSVKMASVLLKHXADVN 1279

Query: 271  TRTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQ 330
             R   + TPLH  A  GH+ + E L+ HGA   A+ K+ L+P+  A   +  D VR LL+
Sbjct: 1278 ARNNVDRTPLHIXAIEGHLGLVEELVRHGADFNAEDKDHLTPVFNACVKNDTDIVRYLLE 1099

Query: 331  YNAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGF-TPLHIACKKNHIR 389
              A  +        P+  A   G+  + ++LL  GA  NS  L G  +PLHIAC+  +I 
Sbjct: 1098 SGARANTTA----RPIFHAVKYGYSEIVQLLLVHGAAVNS--LPGTKSPLHIACRNGNIE 937

Query: 390  VMELLLKTGASIDAVTESGLTPLHVASFM-GHLPIVKNLLQRGASPNVSNVKVETPLHMA 448
            +   ++  GA+++AV + G TPLH++        +V+ L++ GA+    N   + PLH+A
Sbjct: 936  MARTVIIAGANVNAVDKDGNTPLHISVRAPSSAQLVRLLIRFGANVKWGNDNQQIPLHLA 757

Query: 449  ARAGHTEVXXXXXXXXXXXXXXXXXXXTPLHCAARIGHTGMVKLLLENGASPNLATTAGH 508
                + E                                   +LLL  G+  N  ++   
Sbjct: 756  CLYSNLET---------------------------------ARLLLHCGSCSNELSSKLW 676

Query: 509  TPLHTAAREGHVDTALALLEKEASQACMTKKGFTPLHVAAKYGKVRLAELLLEHDAHPNA 568
            TPLH A   G+VD    +L+  +       +   PLH+A     + +A  LL H A+ N 
Sbjct: 675  TPLHYAVIGGNVDIVRLVLQGSSDVNSPDGRNNAPLHLACMKQCIGIARCLLRHGANVNV 496

Query: 569  AGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTP 609
            +G NG TPLH+A+ H+NL++V LL   G +     ++G  P
Sbjct: 495  SGYNGRTPLHIAISHHNLELVLLLYMCGANDQLVDFDGNFP 373

 Score =  146 bits (369), Expect = 6e-35,   Method: Compositional matrix adjust.
 Identities = 114/385 (29%), Positives = 184/385 (47%), Gaps = 1/385 (0%)
 Frame = -2

Query: 28   NLDKALDHLRNGVDINTCNQNGLNGLHLASKEGHVKMVVELLHKEIILETTTKKGNTALH 87
            +++  L +L  G+ ++T + +    LH     G VKM   LL     +        T LH
Sbjct: 1425 DVETLLAYLDIGMHVDTRDSHHETALHAVCYVGSVKMASVLLKHXADVNARNNVDRTPLH 1246

Query: 88   IAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQNVATED 147
            I A+ G   +V ELV +GA+ NA+ +   TP++ A  +N  ++V++LLE+GA  N     
Sbjct: 1245 IXAIEGHLGLVEELVRHGADFNAEDKDHLTPVFNACVKNDTDIVRYLLESGARANTTARP 1066

Query: 148  GFTPLAVALQQGHENVVAHLINYGTKGKVRLPALHIAARNDDTRTAAVLLQNDPNPDVLS 207
             F                H + YG    V+L  +H AA N    T               
Sbjct: 1065 IF----------------HAVKYGYSEIVQLLLVHGAAVNSLPGTK-------------- 976

Query: 208  KTGFTPLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIASRR-GNVIMVRLLLDRG 266
                +PLHIA    N+ +A+ ++  GA+VN   ++G TPLHI+ R   +  +VRLL+  G
Sbjct: 975  ----SPLHIACRNGNIEMARTVIIAGANVNAVDKDGNTPLHISVRAPSSAQLVRLLIRFG 808

Query: 267  AQIETRTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVR 326
            A ++    ++  PLH A    ++  + +LL  G+     +    +P+H A  G ++D VR
Sbjct: 807  ANVKWGNDNQQIPLHLACLYSNLETARLLLHCGSCSNELSSKLWTPLHYAVIGGNVDIVR 628

Query: 327  LLLQYNAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKN 386
            L+LQ +++++     +  PLH+A       +A+ LL  GA  N    NG TPLHIA   +
Sbjct: 627  LVLQGSSDVNSPDGRNNAPLHLACMKQCIGIARCLLRHGANVNVSGYNGRTPLHIAISHH 448

Query: 387  HIRVMELLLKTGASIDAVTESGLTP 411
            ++ ++ LL   GA+   V   G  P
Sbjct: 447  NLELVLLLYMCGANDQLVDFDGNFP 373

 Score =  143 bits (360), Expect = 7e-34,   Method: Compositional matrix adjust.
 Identities = 110/382 (28%), Positives = 181/382 (47%), Gaps = 1/382 (0%)
 Frame = -2

Query: 53   LHLASKEGHVKMVVELLHKEIILETTTKKGNTALHIAALAGQDEVVRELVNYGANVNAQS 112
            LH A +   V+ ++  L   + ++T      TALH     G  ++   L+ + A+VNA++
Sbjct: 1449 LHCAXQLQDVETLLAYLDIGMHVDTRDSHHETALHAVCYVGSVKMASVLLKHXADVNARN 1270

Query: 113  QKGFTPLYMAAQENHLEVVKFLLENGANQNVATEDGFTPLAVALQQGHENVVAHLINYGT 172
                TPL++ A E HL +V+ L+ +GA+ N   +D  TP+  A  +   ++V +L+  G 
Sbjct: 1269 NVDRTPLHIXAIEGHLGLVEELVRHGADFNAEDKDHLTPVFNACVKNDTDIVRYLLESGA 1090

Query: 173  KGKVRLPALHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNR 232
            +                                 + T   P+  A  Y    + QLLL  
Sbjct: 1089 R---------------------------------ANTTARPIFHAVKYGYSEIVQLLLVH 1009

Query: 233  GASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETRTKDELTPLHCAARN-GHVRI 291
            GA+VN  P    +PLHIA R GN+ M R ++  GA +    KD  TPLH + R     ++
Sbjct: 1008 GAAVNSLPGTK-SPLHIACRNGNIEMARTVIIAGANVNAVDKDGNTPLHISVRAPSSAQL 832

Query: 292  SEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYNAEIDDITLDHLTPLHVAAH 351
              +L+  GA ++    N   P+H+A    +L+  RLLL   +  ++++    TPLH A  
Sbjct: 831  VRLLIRFGANVKWGNDNQQIPLHLACLYSNLETARLLLHCGSCSNELSSKLWTPLHYAVI 652

Query: 352  CGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHIRVMELLLKTGASIDAVTESGLTP 411
             G+  + +++L   +  NS       PLH+AC K  I +   LL+ GA+++    +G TP
Sbjct: 651  GGNVDIVRLVLQGSSDVNSPDGRNNAPLHLACMKQCIGIARCLLRHGANVNVSGYNGRTP 472

Query: 412  LHVASFMGHLPIVKNLLQRGAS 433
            LH+A    +L +V  L   GA+
Sbjct: 471  LHIAISHHNLELVLLLYMCGAN 406

 Score =  142 bits (358), Expect = 1e-33,   Method: Compositional matrix adjust.
 Identities = 113/370 (30%), Positives = 167/370 (45%), Gaps = 4/370 (1%)
 Frame = -2

Query: 310  LSPIHMAAQGDHLDCVRLLLQYNAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPN 369
               +H A Q   ++ +   L     +D     H T LH   + G  ++A VLL   A  N
Sbjct: 1458 FCALHCAXQLQDVETLLAYLDIGMHVDTRDSHHETALHAVCYVGSVKMASVLLKHXADVN 1279

Query: 370  SRALNGFTPLHIACKKNHIRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQ 429
            +R     TPLHI   + H+ ++E L++ GA  +A  +  LTP+  A       IV+ LL+
Sbjct: 1278 ARNNVDRTPLHIXAIEGHLGLVEELVRHGADFNAEDKDHLTPVFNACVKNDTDIVRYLLE 1099

Query: 430  RGASPNVSNVKVETPLHMAARAGHTEVXXXXXXXXXXXXXXXXXXXTPLHCAARIGHTGM 489
             GA  N +      P+  A + G++E+                   +PLH A R G+  M
Sbjct: 1098 SGARANTT----ARPIFHAVKYGYSEIVQLLLVHGAAVNSLPGTK-SPLHIACRNGNIEM 934

Query: 490  VKLLLENGASPNLATTAGHTPLHTAAREGHVDTALALLEKEASQACMTKKGF----TPLH 545
             + ++  GA+ N     G+TPLH + R       + LL +  +     K G      PLH
Sbjct: 933  ARTVIIAGANVNAVDKDGNTPLHISVRAPSSAQLVRLLIRFGAN---VKWGNDNQQIPLH 763

Query: 546  VAAKYGKVRLAELLLEHDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWN 605
            +A  Y  +  A LLL   +  N       TPLH AV   N+DIV+L+L      +SP   
Sbjct: 762  LACLYSNLETARLLLHCGSCSNELSSKLWTPLHYAVIGGNVDIVRLVLQGSSDVNSPDGR 583

Query: 606  GYTPLHIAAKQNQIEVARSLLQYGGSANAESVQGVTPLHLAAQEGHTEMVALLLSKQANG 665
               PLH+A  +  I +AR LL++G + N     G TPLH+A    + E+V LL    AN 
Sbjct: 582  NNAPLHLACMKQCIGIARCLLRHGANVNVSGYNGRTPLHIAISHHNLELVLLLYMCGAND 403

Query: 666  NLGNKSGLTP 675
             L +  G  P
Sbjct: 402  QLVDFDGNFP 373

 Score =  138 bits (348), Expect = 2e-32,   Method: Compositional matrix adjust.
 Identities = 108/358 (30%), Positives = 170/358 (47%), Gaps = 3/358 (0%)
 Frame = -2

Query: 376  FTPLHIACKKNHIRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPN 435
            F  LH A +   +  +   L  G  +D       T LH   ++G + +   LL+  A  N
Sbjct: 1458 FCALHCAXQLQDVETLLAYLDIGMHVDTRDSHHETALHAVCYVGSVKMASVLLKHXADVN 1279

Query: 436  VSNVKVETPLHMAARAGHTEVXXXXXXXXXXXXXXXXXXXTPLHCAARIGHTGMVKLLLE 495
              N    TPLH+ A  GH  +                   TP+  A     T +V+ LLE
Sbjct: 1278 ARNNVDRTPLHIXAIEGHLGLVEELVRHGADFNAEDKDHLTPVFNACVKNDTDIVRYLLE 1099

Query: 496  NGASPNLATTAGHTPLHTAAREGHVDTALALLEKEASQACM--TKKGFTPLHVAAKYGKV 553
            +GA  N  TTA   P+  A + G+ +    LL   A+   +  TK   +PLH+A + G +
Sbjct: 1098 SGARAN--TTA--RPIFHAVKYGYSEIVQLLLVHGAAVNSLPGTK---SPLHIACRNGNI 940

Query: 554  RLAELLLEHDAHPNAAGKNGLTPLHVAVHH-NNLDIVKLLLPRGGSPHSPAWNGYTPLHI 612
             +A  ++   A+ NA  K+G TPLH++V   ++  +V+LL+  G +      N   PLH+
Sbjct: 939  EMARTVIIAGANVNAVDKDGNTPLHISVRAPSSAQLVRLLIRFGANVKWGNDNQQIPLHL 760

Query: 613  AAKQNQIEVARSLLQYGGSANAESVQGVTPLHLAAQEGHTEMVALLLSKQANGNLGNKSG 672
            A   + +E AR LL  G  +N  S +  TPLH A   G+ ++V L+L   ++ N  +   
Sbjct: 759  ACLYSNLETARLLLHCGSCSNELSSKLWTPLHYAVIGGNVDIVRLVLQGSSDVNSPDGRN 580

Query: 673  LTPLHLVSQEGHVPVADVLIKHGVTVDATTRMGYTPLHVASHYGNIKLVKFLLQHQAD 730
              PLHL   +  + +A  L++HG  V+ +   G TPLH+A  + N++LV  L    A+
Sbjct: 579  NAPLHLACMKQCIGIARCLLRHGANVNVSGYNGRTPLHIAISHHNLELVLLLYMCGAN 406

 Score =  136 bits (343), Expect = 7e-32,   Method: Compositional matrix adjust.
 Identities = 100/305 (32%), Positives = 147/305 (48%), Gaps = 2/305 (0%)
 Frame = -2

Query: 476  TPLHCAARIGHTGMVKLLLENGASPNLATTAGHTPLHTAAREGHVDTALALLEKEASQAC 535
            T LH    +G   M  +LL++ A  N       TPLH  A EGH+     L+   A    
Sbjct: 1356 TALHAVCYVGSVKMASVLLKHXADVNARNNVDRTPLHIXAIEGHLGLVEELVRHGADFNA 1177

Query: 536  MTKKGFTPLHVAAKYGKVRLAELLLEHDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPR 595
              K   TP+  A       +   LLE  A  N   +    P+  AV +   +IV+LLL  
Sbjct: 1176 EDKDHLTPVFNACVKNDTDIVRYLLESGARANTTAR----PIFHAVKYGYSEIVQLLLVH 1009

Query: 596  GGSPHS-PAWNGYTPLHIAAKQNQIEVARSLLQYGGSANAESVQGVTPLHLAAQE-GHTE 653
            G + +S P     +PLHIA +   IE+AR+++  G + NA    G TPLH++ +     +
Sbjct: 1008 GAAVNSLPGTK--SPLHIACRNGNIEMARTVIIAGANVNAVDKDGNTPLHISVRAPSSAQ 835

Query: 654  MVALLLSKQANGNLGNKSGLTPLHLVSQEGHVPVADVLIKHGVTVDATTRMGYTPLHVAS 713
            +V LL+   AN   GN +   PLHL     ++  A +L+  G   +  +   +TPLH A 
Sbjct: 834  LVRLLIRFGANVKWGNDNQQIPLHLACLYSNLETARLLLHCGSCSNELSSKLWTPLHYAV 655

Query: 714  HYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGASPNEVSSNGTT 773
              GN+ +V+ +LQ  +DVN+      +PLH A  +    I   LL++GA+ N    NG T
Sbjct: 654  IGGNVDIVRLVLQGSSDVNSPDGRNNAPLHLACMKQCIGIARCLLRHGANVNVSGYNGRT 475

Query: 774  PLAIA 778
            PL IA
Sbjct: 474  PLHIA 460

 Score =  108 bits (269), Expect = 3e-23,   Method: Compositional matrix adjust.
 Identities = 92/298 (30%), Positives = 144/298 (48%), Gaps = 3/298 (1%)
 Frame = -2

Query: 506  AGHTPLHTAAREGHVDTALALLEKEASQACMTKKGFTPLHVAAKYGKVRLAELLLEHDAH 565
            A    LH A +   V+T LA L+             T LH     G V++A +LL+H A 
Sbjct: 1464 ASFCALHCAXQLQDVETLLAYLDIGMHVDTRDSHHETALHAVCYVGSVKMASVLLKHXAD 1285

Query: 566  PNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQIEVARSL 625
             NA      TPLH+     +L +V+ L+  G   ++   +  TP+  A  +N  ++ R L
Sbjct: 1284 VNARNNVDRTPLHIXAIEGHLGLVEELVRHGADFNAEDKDHLTPVFNACVKNDTDIVRYL 1105

Query: 626  LQYGGSANAESVQGVTPLHLAAQEGHTEMVALLLSKQANGNL--GNKSGLTPLHLVSQEG 683
            L+ G  AN  +     P+  A + G++E+V LLL   A  N   G KS   PLH+  + G
Sbjct: 1104 LESGARANTTA----RPIFHAVKYGYSEIVQLLLVHGAAVNSLPGTKS---PLHIACRNG 946

Query: 684  HVPVADVLIKHGVTVDATTRMGYTPLHVASHY-GNIKLVKFLLQHQADVNAKTKLGYSPL 742
            ++ +A  +I  G  V+A  + G TPLH++     + +LV+ L++  A+V         PL
Sbjct: 945  NIEMARTVIIAGANVNAVDKDGNTPLHISVRAPSSAQLVRLLIRFGANVKWGNDNQQIPL 766

Query: 743  HQAAQQGHTDIVTLLLKNGASPNEVSSNGTTPLAIAKRLGYISVTDVLKVVTDETSVV 800
            H A    + +   LLL  G+  NE+SS   TPL  A   G +   D++++V   +S V
Sbjct: 765  HLACLYSNLETARLLLHCGSCSNELSSKLWTPLHYAVIGGNV---DIVRLVLQGSSDV 601

 Score = 55.8 bits (133), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 34/108 (31%), Positives = 53/108 (49%)
 Frame = -2

Query: 53  LHLASKEGHVKMVVELLHKEIILETTTKKGNTALHIAALAGQDEVVRELVNYGANVNAQS 112
           LH A   G+V +V  +L     + +   + N  LH+A +     + R L+ +GANVN   
Sbjct: 669 LHYAVIGGNVDIVRLVLQGSSDVNSPDGRNNAPLHLACMKQCIGIARCLLRHGANVNVSG 490

Query: 113 QKGFTPLYMAAQENHLEVVKFLLENGANQNVATEDGFTPLAVALQQGH 160
             G TPL++A   ++LE+V  L   GAN  +   DG  P   ++   H
Sbjct: 489 YNGRTPLHIAISHHNLELVLLLYMCGANDQLVDFDGNFPSCYSMCHIH 346
>06253
          Length = 1049

 Score =  134 bits (336), Expect = 5e-31,   Method: Compositional matrix adjust.
 Identities = 90/259 (34%), Positives = 134/259 (51%), Gaps = 22/259 (8%)
 Frame = -1

Query: 542  TPLHVAAKYGKVRLAELLLEHDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHS 601
            TPLH AA +G+  + E LLE+ A+ +A    GL PLH A    + ++V+LLL  G  P++
Sbjct: 1040 TPLHFAAGFGRKDVVEHLLENGANVHARDDGGLIPLHNACSFGHAEVVQLLLRHGADPNA 861

Query: 602  -PAWNGYTPLHIAAKQNQIEVARSLLQYGGSANAESVQGVTPLHLA-------------- 646
               WN YTPLH AA + +I+V   LLQ     N  +  G T L LA              
Sbjct: 860  RDNWN-YTPLHEAAIKGKIDVCIVLLQQCADPNIRNTDGKTALDLADASAKAVLTGEYKK 684

Query: 647  ------AQEGHTE-MVALLLSKQANGNLGNKSGLTPLHLVSQEGHVPVADVLIKHGVTVD 699
                  A+ G+ E M+ALL     N +  +    TPLHL +      +  +L++HG  V 
Sbjct: 683  DELLEAARSGNEEQMMALLTPLNVNCHASDGRKSTPLHLAAGYNRTRIVQLLLQHGADVH 504

Query: 700  ATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLK 759
            A  + G  PLH A  YG+ ++ + LL   A VNA     ++PLH+AA +   ++ +LLL 
Sbjct: 503  AKDKGGLVPLHNACSYGHFEVTEMLLXAGASVNAVDLWQFTPLHEAASKSRVEVCSLLLA 324

Query: 760  NGASPNEVSSNGTTPLAIA 778
            +GA PN V+ +  + + +A
Sbjct: 323  HGADPNLVNCHSKSIIDVA 267

 Score =  119 bits (297), Expect = 1e-26,   Method: Compositional matrix adjust.
 Identities = 86/245 (35%), Positives = 113/245 (46%), Gaps = 21/245 (8%)
 Frame = -1

Query: 344  TPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHIRVMELLLKTGASIDA 403
            TPLH AA  G   V + LL+ GA  ++R   G  PLH AC   H  V++LLL+ GA  +A
Sbjct: 1040 TPLHFAAGFGRKDVVEHLLENGANVHARDDGGLIPLHNACSFGHAEVVQLLLRHGADPNA 861

Query: 404  VTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMA--------------- 448
                  TPLH A+  G + +   LLQ+ A PN+ N   +T L +A               
Sbjct: 860  RDNWNYTPLHEAAIKGKIDVCIVLLQQCADPNIRNTDGKTALDLADASAKAVLTGEYKKD 681

Query: 449  -----ARAGHTE-VXXXXXXXXXXXXXXXXXXXTPLHCAARIGHTGMVKLLLENGASPNL 502
                 AR+G+ E +                   TPLH AA    T +V+LLL++GA  + 
Sbjct: 680  ELLEAARSGNEEQMMALLTPLNVNCHASDGRKSTPLHLAAGYNRTRIVQLLLQHGADVHA 501

Query: 503  ATTAGHTPLHTAAREGHVDTALALLEKEASQACMTKKGFTPLHVAAKYGKVRLAELLLEH 562
                G  PLH A   GH +    LL   AS   +    FTPLH AA   +V +  LLL H
Sbjct: 500  KDKGGLVPLHNACSYGHFEVTEMLLXAGASVNAVDLWQFTPLHEAASKSRVEVCSLLLAH 321

Query: 563  DAHPN 567
             A PN
Sbjct: 320  GADPN 306

 Score =  113 bits (282), Expect = 8e-25,   Method: Compositional matrix adjust.
 Identities = 81/258 (31%), Positives = 118/258 (45%), Gaps = 21/258 (8%)
 Frame = -1

Query: 212  TPLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIET 271
            TPLH AA +   +V + LL  GA+V+     G+ PLH A   G+  +V+LLL  GA    
Sbjct: 1040 TPLHFAAGFGRKDVVEHLLENGANVHARDDGGLIPLHNACSFGHAEVVQLLLRHGADPNA 861

Query: 272  RTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMA--------------- 316
            R     TPLH AA  G + +  +LL   A    +  +G + + +A               
Sbjct: 860  RDNWNYTPLHEAAIKGKIDVCIVLLQQCADPNIRNTDGKTALDLADASAKAVLTGEYKKD 681

Query: 317  ------AQGDHLDCVRLLLQYNAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNS 370
                    G+    + LL   N           TPLH+AA     R+ ++LL  GA  ++
Sbjct: 680  ELLEAARSGNEEQMMALLTPLNVNCHASDGRKSTPLHLAAGYNRTRIVQLLLQHGADVHA 501

Query: 371  RALNGFTPLHIACKKNHIRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQR 430
            +   G  PLH AC   H  V E+LL  GAS++AV     TPLH A+    + +   LL  
Sbjct: 500  KDKGGLVPLHNACSYGHFEVTEMLLXAGASVNAVDLWQFTPLHEAASKSRVEVCSLLLAH 321

Query: 431  GASPNVSNVKVETPLHMA 448
            GA PN+ N   ++ + +A
Sbjct: 320  GADPNLVNCHSKSIIDVA 267

 Score =  110 bits (275), Expect = 5e-24,   Method: Compositional matrix adjust.
 Identities = 79/241 (32%), Positives = 111/241 (46%), Gaps = 21/241 (8%)
 Frame = -1

Query: 476  TPLHCAARIGHTGMVKLLLENGASPNLATTAGHTPLHTAAREGHVDTALALLEKEASQAC 535
            TPLH AA  G   +V+ LLENGA+ +     G  PLH A   GH +    LL   A    
Sbjct: 1040 TPLHFAAGFGRKDVVEHLLENGANVHARDDGGLIPLHNACSFGHAEVVQLLLRHGADPNA 861

Query: 536  MTKKGFTPLHVAAKYGKVRLAELLLEHDAHPNAAGKNGLTPLHV---------------- 579
                 +TPLH AA  GK+ +  +LL+  A PN    +G T L +                
Sbjct: 860  RDNWNYTPLHEAAIKGKIDVCIVLLQQCADPNIRNTDGKTALDLADASAKAVLTGEYKKD 681

Query: 580  -----AVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQIEVARSLLQYGGSANA 634
                 A   N   ++ LL P   + H+      TPLH+AA  N+  + + LLQ+G   +A
Sbjct: 680  ELLEAARSGNEEQMMALLTPLNVNCHASDGRKSTPLHLAAGYNRTRIVQLLLQHGADVHA 501

Query: 635  ESVQGVTPLHLAAQEGHTEMVALLLSKQANGNLGNKSGLTPLHLVSQEGHVPVADVLIKH 694
            +   G+ PLH A   GH E+  +LL   A+ N  +    TPLH  + +  V V  +L+ H
Sbjct: 500  KDKGGLVPLHNACSYGHFEVTEMLLXAGASVNAVDLWQFTPLHEAASKSRVEVCSLLLAH 321

Query: 695  G 695
            G
Sbjct: 320  G 318

 Score =  105 bits (262), Expect = 2e-22,   Method: Compositional matrix adjust.
 Identities = 79/245 (32%), Positives = 111/245 (45%), Gaps = 25/245 (10%)
 Frame = -1

Query: 81   KGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGAN 140
            + +T LH AA  G+ +VV  L+  GANV+A+   G  PL+ A    H EVV+ LL +GA+
Sbjct: 1049 RKSTPLHFAAGFGRKDVVEHLLENGANVHARDDGGLIPLHNACSFGHAEVVQLLLRHGAD 870

Query: 141  QNVATEDGFTPLAVALQQGHENVVAHLINY-------GTKGKVRL--------------- 178
             N      +TPL  A  +G  +V   L+          T GK  L               
Sbjct: 869  PNARDNWNYTPLHEAAIKGKIDVCIVLLQQCADPNIRNTDGKTALDLADASAKAVLTGEY 690

Query: 179  ---PALHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGAS 235
                 L  A   ++ +  A+L   + N         TPLH+AA Y    + QLLL  GA 
Sbjct: 689  KKDELLEAARSGNEEQMMALLTPLNVNCHASDGRKSTPLHLAAGYNRTRIVQLLLQHGAD 510

Query: 236  VNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETRTKDELTPLHCAARNGHVRISEIL 295
            V+   + G+ PLH A   G+  +  +LL  GA +      + TPLH AA    V +  +L
Sbjct: 509  VHAKDKGGLVPLHNACSYGHFEVTEMLLXAGASVNAVDLWQFTPLHEAASKSRVEVCSLL 330

Query: 296  LDHGA 300
            L HGA
Sbjct: 329  LAHGA 315

 Score = 61.6 bits (148), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 85/338 (25%), Positives = 129/338 (38%), Gaps = 83/338 (24%)
 Frame = -1

Query: 53   LHLASKEGHVKMVVELLHKEIILETTTKKGNTALHIAALAGQDEVVRELVNYGANVNAQS 112
            LH A+  G   +V  LL     +      G   LH A   G  EVV+ L+ +GA+ NA+ 
Sbjct: 1034 LHFAAGFGRKDVVEHLLENGANVHARDDGGLIPLHNACSFGHAEVVQLLLRHGADPNARD 855

Query: 113  QKGFTPLYMAAQENHLEVVKFLLENGANQNVATEDGFTPLAVA----------------- 155
               +TPL+ AA +  ++V   LL+  A+ N+   DG T L +A                 
Sbjct: 854  NWNYTPLHEAAIKGKIDVCIVLLQQCADPNIRNTDGKTALDLADASAKAVLTGEYKKDEL 675

Query: 156  ---LQQGHENVVAHLIN------YGTKGKVRLPALHIAARNDDTRTAAVLLQNDPNPDVL 206
                + G+E  +  L+       + + G+   P LH+AA  + TR   +LLQ+  +    
Sbjct: 674  LEAARSGNEEQMMALLTPLNVNCHASDGRKSTP-LHLAAGYNRTRIVQLLLQHGADVHAK 498

Query: 207  SKTG---------------------------------FTPLHIAAHYENLNVAQLLLNRG 233
             K G                                 FTPLH AA    + V  LLL  G
Sbjct: 497  DKGGLVPLHNACSYGHFEVTEMLLXAGASVNAVDLWQFTPLHEAASKSRVEVCSLLLAHG 318

Query: 234  ASVNFTPQNGITPLHIASRRGNVIMVRL------LLDRGAQIE-TRTKDEL--------- 277
            A  N    +  + + +A  R     ++       LL+   Q +  R K  L         
Sbjct: 317  ADPNLVNCHSKSIIDVAPTRELQERIQFEYKGHSLLEGARQADLARVKKYLAVDIVNFKH 138

Query: 278  -----TPLHCAARN---GHVRISEILLDHGAPIQAKTK 307
                 T LHCAA +      ++ E+L+  G  +  KTK
Sbjct: 137  PYNGDTALHCAAASPFPKRKQVVELLVRKGGNLNEKTK 24

 Score = 60.5 bits (145), Expect = 6e-09,   Method: Compositional matrix adjust.
 Identities = 78/308 (25%), Positives = 119/308 (38%), Gaps = 40/308 (12%)
 Frame = -1

Query: 7   RSGSDPAAD---AATSFLRAARSGNLDKALDHLRNGVDINTCNQNGLNGLHLASKEGHVK 63
           R G+DP A      T    AA  G +D  +  L+   D N  N +G   L LA       
Sbjct: 884 RHGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQQCADPNIRNTDGKTALDLADASAKAV 705

Query: 64  MVVELLHKEII---------------------LETTTKKGNTALHIAALAGQDEVVRELV 102
           +  E    E++                        +  + +T LH+AA   +  +V+ L+
Sbjct: 704 LTGEYKKDELLEAARSGNEEQMMALLTPLNVNCHASDGRKSTPLHLAAGYNRTRIVQLLL 525

Query: 103 NYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQNVATEDGFTPLAVALQQGHEN 162
            +GA+V+A+ + G  PL+ A    H EV + LL  GA+ N      FTPL  A  +    
Sbjct: 524 QHGADVHAKDKGGLVPLHNACSYGHFEVTEMLLXAGASVNAVDLWQFTPLHEAASKSRVE 345

Query: 163 V----VAH-----LINYGTKGKVRL-PALHIAARNDDTRTAAVLLQNDPNPDVLSKTGFT 212
           V    +AH     L+N  +K  + + P   +  R         LL+     D+     + 
Sbjct: 344 VCSLLLAHGADPNLVNCHSKSIIDVAPTRELQERIQFEYKGHSLLEGARQADLARVKKYL 165

Query: 213 PLHIAAHYENLNVAQLLLNRGASVNFT-PQNGITPLHIAS-----RRGNVIMVRLLLDRG 266
            + I                   VNF  P NG T LH A+     +R  V  V LL+ +G
Sbjct: 164 AVDI-------------------VNFKHPYNGDTALHCAAASPFPKRKQV--VELLVRKG 48

Query: 267 AQIETRTK 274
             +  +TK
Sbjct: 47  GNLNEKTK 24
>11295
          Length = 1179

 Score =  119 bits (297), Expect = 1e-26,   Method: Compositional matrix adjust.
 Identities = 102/359 (28%), Positives = 148/359 (41%), Gaps = 1/359 (0%)
 Frame = +1

Query: 96  EVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQNVATEDGFTPLAVA 155
           + V  L+  GA +     +G + L+ A    + EV + LL+      +A          A
Sbjct: 7   QTVLTLLQGGAQIYWTDHRGLSALHHACIGRNTEVAELLLDGWNGDGIAVN--------A 162

Query: 156 LQQGHENVVAHLINYGTKGKVRLPALHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLH 215
               H                 + ALHIA   DD   A++LL+       L   G TPLH
Sbjct: 163 TSNDH-----------------VTALHIACCLDDREMASLLLKYGAYAMALDVIGHTPLH 291

Query: 216 IAAHYENLNVAQLLLNRG-ASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETRTK 274
           +A    +  V +LLL+R    VN    +G  PL +AS  G   ++R LL   A    R  
Sbjct: 292 VACWCGSEGVTRLLLDRSDVDVNALDHDGKXPLRLASECGFHYIIRQLLYHNADHTIRDA 471

Query: 275 DELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYNAE 334
            E TP HCA R   V   +  L     +     N LSP  MA            LQ + E
Sbjct: 472 AEFTPFHCAIRYCRVLAVKTFLVWFPDLIHSFYNDLSPTFMAC-----------LQCDKE 618

Query: 335 IDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHIRVMELL 394
           +                        +L+  GA  N      +TPLH   ++ H+ +++LL
Sbjct: 619 M----------------------LSLLIKFGASVNCADHYHYTPLHYISRRGHLTMLQLL 732

Query: 395 LKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGH 453
           L+  A  + V + G+TPL++AS  GH+ IV  LLQ GA   +   +   P+H A +AGH
Sbjct: 733 LQGKAEPNVVDDEGITPLYIASCEGHVTIVNILLQSGAKIYMPCAR--DPVHAACKAGH 903

 Score =  106 bits (264), Expect = 1e-22,   Method: Compositional matrix adjust.
 Identities = 97/345 (28%), Positives = 141/345 (40%), Gaps = 5/345 (1%)
 Frame = +1

Query: 189 DTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLN----RGASVNFTPQNGI 244
           D +T   LLQ           G + LH A    N  VA+LLL+     G +VN T  + +
Sbjct: 1   DRQTVLTLLQGGAQIYWTDHRGLSALHHACIGRNTEVAELLLDGWNGDGIAVNATSNDHV 180

Query: 245 TPLHIASRRGNVIMVRLLLDRGAQIETRTKDELTPLHCAARNGHVRISEILLDHG-APIQ 303
           T LHIA    +  M  LLL  GA          TPLH A   G   ++ +LLD     + 
Sbjct: 181 TALHIACCLDDREMASLLLKYGAYAMALDVIGHTPLHVACWCGSEGVTRLLLDRSDVDVN 360

Query: 304 AKTKNGLSPIHMAAQGDHLDCVRLLLQYNAEIDDITLDHLTPLHVAAHCGHHRVAKVLLD 363
           A   +G  P+ +A++      +R LL +NA+         TP H A         K  L 
Sbjct: 361 ALDHDGKXPLRLASECGFHYIIRQLLYHNADHTIRDAAEFTPFHCAIRYCRVLAVKTFLV 540

Query: 364 KGAKPNSRALNGFTPLHIACKKNHIRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPI 423
                     N  +P  +AC +    ++ LL+K GAS++       TPLH  S  GHL +
Sbjct: 541 WFPDLIHSFYNDLSPTFMACLQCDKEMLSLLIKFGASVNCADHYHYTPLHYISRRGHLTM 720

Query: 424 VKNLLQRGASPNVSNVKVETPLHMAARAGHTEVXXXXXXXXXXXXXXXXXXXTPLHCAAR 483
           ++ LLQ  A PNV + +  TPL++A+  GH  +                           
Sbjct: 721 LQLLLQGKAEPNVVDDEGITPLYIASCEGHVTI--------------------------- 819

Query: 484 IGHTGMVKLLLENGASPNLATTAGHTPLHTAAREGHVDTALALLE 528
                 V +LL++GA   +       P+H A + GH   AL   +
Sbjct: 820 ------VNILLQSGA--KIYMPCARDPVHAACKAGHEVIALRFFD 930

 Score =  105 bits (263), Expect = 1e-22,   Method: Compositional matrix adjust.
 Identities = 86/310 (27%), Positives = 131/310 (42%), Gaps = 9/310 (2%)
 Frame = +1

Query: 424 VKNLLQRGASPNVSNVKVETPLHMAARAGHTEVXXXXXXXX----XXXXXXXXXXXTPLH 479
           V  LLQ GA    ++ +  + LH A    +TEV                       T LH
Sbjct: 13  VLTLLQGGAQIYWTDHRGLSALHHACIGRNTEVAELLLDGWNGDGIAVNATSNDHVTALH 192

Query: 480 CAARIGHTGMVKLLLENGASPNLATTAGHTPLHTAAREGHVDTALALLEK-EASQACMTK 538
            A  +    M  LLL+ GA        GHTPLH A   G       LL++ +     +  
Sbjct: 193 IACCLDDREMASLLLKYGAYAMALDVIGHTPLHVACWCGSEGVTRLLLDRSDVDVNALDH 372

Query: 539 KGFTPLHVAAKYGKVRLAELLLEHDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGS 598
            G  PL +A++ G   +   LL H+A          TP H A+ +  +  VK  L     
Sbjct: 373 DGKXPLRLASECGFHYIIRQLLYHNADHTIRDAAEFTPFHCAIRYCRVLAVKTFLVWFPD 552

Query: 599 PHSPAWNGYTPLHIAAKQNQIEVARSLLQYGGSANAESVQGVTPLHLAAQEGHTEMVALL 658
                +N  +P  +A  Q   E+   L+++G S N       TPLH  ++ GH  M+ LL
Sbjct: 553 LIHSFYNDLSPTFMACLQCDKEMLSLLIKFGASVNCADHYHYTPLHYISRRGHLTMLQLL 732

Query: 659 LSKQANGNLGNKSGLTPLHLVSQEGHVPVADVLIKHGVTVDATTRMGYTPLHVASHYGN- 717
           L  +A  N+ +  G+TPL++ S EGHV + ++L++ G  +         P+H A   G+ 
Sbjct: 733 LQGKAEPNVVDDEGITPLYIASCEGHVTIVNILLQSGAKI--YMPCARDPVHAACKAGHE 906

Query: 718 ---IKLVKFL 724
              ++   FL
Sbjct: 907 VIALRFFDFL 936

 Score =  104 bits (259), Expect = 4e-22,   Method: Compositional matrix adjust.
 Identities = 90/296 (30%), Positives = 127/296 (42%), Gaps = 10/296 (3%)
 Frame = +1

Query: 36  LRNGVDINTCNQNGLNGLHLASKEGHVKMVVELL-----HKEIILETTTKKGNTALHIAA 90
           L+ G  I   +  GL+ LH A   G    V ELL        I +  T+    TALHIA 
Sbjct: 25  LQGGAQIYWTDHRGLSALHHACI-GRNTEVAELLLDGWNGDGIAVNATSNDHVTALHIAC 201

Query: 91  LAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLE-NGANQNVATEDGF 149
                E+   L+ YGA   A    G TPL++A       V + LL+ +  + N    DG 
Sbjct: 202 CLDDREMASLLLKYGAYAMALDVIGHTPLHVACWCGSEGVTRLLLDRSDVDVNALDHDGK 381

Query: 150 TPLAVALQQGHENVVAHLINYGTKGKVRLPA----LHIAARNDDTRTAAVLLQNDPNPDV 205
            PL +A + G   ++  L+ +     +R  A     H A R          L   P+   
Sbjct: 382 XPLRLASECGFHYIIRQLLYHNADHTIRDAAEFTPFHCAIRYCRVLAVKTFLVWFPDLIH 561

Query: 206 LSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDR 265
                 +P  +A    +  +  LL+  GASVN       TPLH  SRRG++ M++LLL  
Sbjct: 562 SFYNDLSPTFMACLQCDKEMLSLLIKFGASVNCADHYHYTPLHYISRRGHLTMLQLLLQG 741

Query: 266 GAQIETRTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDH 321
            A+      + +TPL+ A+  GHV I  ILL  GA I         P+H A +  H
Sbjct: 742 KAEPNVVDDEGITPLYIASCEGHVTIVNILLQSGAKIYMPCAR--DPVHAACKAGH 903

 Score =  100 bits (249), Expect = 6e-21,   Method: Compositional matrix adjust.
 Identities = 76/274 (27%), Positives = 124/274 (45%), Gaps = 5/274 (1%)
 Frame = +1

Query: 522 TALALLEKEASQACMTKKGFTPLHVAAKYGKVRLAELLLE----HDAHPNAAGKNGLTPL 577
           T L LL+  A       +G + LH A       +AELLL+         NA   + +T L
Sbjct: 10  TVLTLLQGGAQIYWTDHRGLSALHHACIGRNTEVAELLLDGWNGDGIAVNATSNDHVTAL 189

Query: 578 HVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQIEVARSLLQYGG-SANAES 636
           H+A   ++ ++  LLL  G    +    G+TPLH+A       V R LL       NA  
Sbjct: 190 HIACCLDDREMASLLLKYGAYAMALDVIGHTPLHVACWCGSEGVTRLLLDRSDVDVNALD 369

Query: 637 VQGVTPLHLAAQEGHTEMVALLLSKQANGNLGNKSGLTPLHLVSQEGHVPVADVLIKHGV 696
             G  PL LA++ G   ++  LL   A+  + + +  TP H   +   V      +    
Sbjct: 370 HDGKXPLRLASECGFHYIIRQLLYHNADHTIRDAAEFTPFHCAIRYCRVLAVKTFLVWFP 549

Query: 697 TVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTL 756
            +  +     +P  +A    + +++  L++  A VN      Y+PLH  +++GH  ++ L
Sbjct: 550 DLIHSFYNDLSPTFMACLQCDKEMLSLLIKFGASVNCADHYHYTPLHYISRRGHLTMLQL 729

Query: 757 LLKNGASPNEVSSNGTTPLAIAKRLGYISVTDVL 790
           LL+  A PN V   G TPL IA   G++++ ++L
Sbjct: 730 LLQGKAEPNVVDDEGITPLYIASCEGHVTIVNIL 831

 Score = 91.7 bits (226), Expect = 3e-18,   Method: Compositional matrix adjust.
 Identities = 84/320 (26%), Positives = 141/320 (44%), Gaps = 9/320 (2%)
 Frame = +1

Query: 476 TPLHCAARIGHTGMVKLLLE----NGASPNLATTAGHTPLHTAAREGHVDTALALLEKEA 531
           + LH A    +T + +LLL+    +G + N  +    T LH A      + A  LL+  A
Sbjct: 70  SALHHACIGRNTEVAELLLDGWNGDGIAVNATSNDHVTALHIACCLDDREMASLLLKYGA 249

Query: 532 SQACMTKKGFTPLHVAAKYGKVRLAELLLEH-DAHPNAAGKNGLTPLHVAVHHNNLDIVK 590
               +   G TPLHVA   G   +  LLL+  D   NA   +G  PL +A       I++
Sbjct: 250 YAMALDVIGHTPLHVACWCGSEGVTRLLLDRSDVDVNALDHDGKXPLRLASECGFHYIIR 429

Query: 591 LLLPRGGSPHSPAWNGYTPLHIAAKQNQIEVARSLLQYGGSANAESVQGVTPLHLAAQEG 650
            LL             +TP H A +  ++   ++ L +           ++P  +A  + 
Sbjct: 430 QLLYHNADHTIRDAAEFTPFHCAIRYCRVLAVKTFLVWFPDLIHSFYNDLSPTFMACLQC 609

Query: 651 HTEMVALLLSKQANGNLGNKSGLTPLHLVSQEGHVPVADVLIKHGVTVDATTRMGYTPLH 710
             EM++LL+   A+ N  +    TPLH +S+ GH+ +  +L++     +     G TPL+
Sbjct: 610 DKEMLSLLIKFGASVNCADHYHYTPLHYISRRGHLTMLQLLLQGKAEPNVVDDEGITPLY 789

Query: 711 VASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTL----LLKNGASPNE 766
           +AS  G++ +V  LLQ  A +         P+H A + GH +++ L     L    +   
Sbjct: 790 IASCEGHVTIVNILLQSGAKI--YMPCARDPVHAACKAGH-EVIALRFFDFLGEKLNAKG 960

Query: 767 VSSNGTTPLAIAKRLGYISV 786
           V S     +A+A R  Y+ +
Sbjct: 961 VCSTMCRSVALAIRRLYMYM 1020

 Score = 85.1 bits (209), Expect = 2e-16,   Method: Compositional matrix adjust.
 Identities = 81/260 (31%), Positives = 110/260 (42%), Gaps = 22/260 (8%)
 Frame = +1

Query: 559 LLEHDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNG------------ 606
           LL+  A        GL+ LH A    N ++ +LLL          WNG            
Sbjct: 22  LLQGGAQIYWTDHRGLSALHHACIGRNTEVAELLLD--------GWNGDGIAVNATSNDH 177

Query: 607 YTPLHIAAKQNQIEVARSLLQYGGSANAESVQGVTPLHLAAQEGHTEMVALLLSKQ-ANG 665
            T LHIA   +  E+A  LL+YG  A A  V G TPLH+A   G   +  LLL +   + 
Sbjct: 178 VTALHIACCLDDREMASLLLKYGAYAMALDVIGHTPLHVACWCGSEGVTRLLLDRSDVDV 357

Query: 666 NLGNKSGLTPLHLVSQEGHVPVADVLIKHGVTVDATTRMG--YTPLHVASHYGNIKLVKF 723
           N  +  G  PL L S+ G   +   L+ H    D T R    +TP H A  Y  +  VK 
Sbjct: 358 NALDHDGKXPLRLASECGFHYIIRQLLYH--NADHTIRDAAEFTPFHCAIRYCRVLAVKT 531

Query: 724 LLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGASPNEVSSNGTTPLAIAKRLGY 783
            L    D+        SP   A  Q   ++++LL+K GAS N       TPL    R G+
Sbjct: 532 FLVWFPDLIHSFYNDLSPTFMACLQCDKEMLSLLIKFGASVNCADHYHYTPLHYISRRGH 711

Query: 784 ISVTDVL-------KVVTDE 796
           +++  +L        VV DE
Sbjct: 712 LTMLQLLLQGKAEPNVVDDE 771

 Score = 43.1 bits (100), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 25/87 (28%), Positives = 43/87 (49%)
 Frame = +1

Query: 84  TALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQNV 143
           T LH  +  G   +++ L+   A  N    +G TPLY+A+ E H+ +V  LL++GA   +
Sbjct: 679 TPLHYISRRGHLTMLQLLLQGKAEPNVVDDEGITPLYIASCEGHVTIVNILLQSGA--KI 852

Query: 144 ATEDGFTPLAVALQQGHENVVAHLINY 170
                  P+  A + GHE +     ++
Sbjct: 853 YMPCARDPVHAACKAGHEVIALRFFDF 933
>14005
          Length = 1745

 Score =  108 bits (270), Expect = 2e-23,   Method: Compositional matrix adjust.
 Identities = 86/265 (32%), Positives = 133/265 (50%), Gaps = 11/265 (4%)
 Frame = -1

Query: 542  TPLHVAAKYGKVRLAELLLEHDAHPNAAGKNGLTP-LHVAVHHNNLDIVKLLLPRGGSPH 600
            TPL +A++ G + +   LL+            L P L+ A   N++++VK L+  G   +
Sbjct: 1739 TPLIIASRMGHLAVVSELLKVPGIDVNERDEKLRPALYFACMGNDIELVKQLVRYGARVN 1560

Query: 601  SPA---WNGYTPLHIAAKQNQIEVARSLLQYGGSANAESVQGVTPLHLAAQEGHTEMVAL 657
            + +   W  +TP H   K+    +A  LL++G +  + +V G TPL +A +    E+  L
Sbjct: 1559 AYSTETW--WTPFHACCKRGDPRIALYLLRHGANKESRTVDGKTPLVVACKNDKAEVALL 1386

Query: 658  LLSKQANGNLG-NKSGLTPLHLVSQEGHVPVADVLIKHGVTVDATTRMGYTPLHVASHYG 716
            L+   AN N+  + +  TP+H   Q  ++ +   L+ HG  VD     G+T LHVAS  G
Sbjct: 1385 LIRSGANVNVSCDITANTPVHFACQRPNIELLKRLVLHGADVDKPNAKGHTALHVASVRG 1206

Query: 717  NIKLVKFLLQH-QADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGASPNEVSSNGTTPL 775
              + V +LL    A+VNA T  G + LH A +  H D+V LLL  GA+P + +  G TP 
Sbjct: 1205 FKQHVIYLLDFCDAEVNAATLKGNNALHIACRGKHADLVELLLHKGANPAQRNQRGWTPR 1026

Query: 776  AIAKRLGYISVTDVL-----KVVTD 795
              A R     V D+L     KV +D
Sbjct: 1025 NSAGRC--XEVLDILDSRI*KVCSD 957

 Score =  103 bits (256), Expect = 9e-22,   Method: Compositional matrix adjust.
 Identities = 74/243 (30%), Positives = 121/243 (49%), Gaps = 4/243 (1%)
 Frame = -1

Query: 278  TPLHCAARNGHVRI-SEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYNAEID 336
            TPL  A+R GH+ + SE+L   G  +  + +     ++ A  G+ ++ V+ L++Y A ++
Sbjct: 1739 TPLIIASRMGHLAVVSELLKVPGIDVNERDEKLRPALYFACMGNDIELVKQLVRYGARVN 1560

Query: 337  DITLD-HLTPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHIRVMELLL 395
              + +   TP H     G  R+A  LL  GA   SR ++G TPL +ACK +   V  LL+
Sbjct: 1559 AYSTETWWTPFHACCKRGDPRIALYLLRHGANKESRTVDGKTPLVVACKNDKAEVALLLI 1380

Query: 396  KTGASIDAVTE-SGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHT 454
            ++GA+++   + +  TP+H A    ++ ++K L+  GA  +  N K  T LH+A+  G  
Sbjct: 1379 RSGANVNVSCDITANTPVHFACQRPNIELLKRLVLHGADVDKPNAKGHTALHVASVRGFK 1200

Query: 455  E-VXXXXXXXXXXXXXXXXXXXTPLHCAARIGHTGMVKLLLENGASPNLATTAGHTPLHT 513
            + V                     LH A R  H  +V+LLL  GA+P      G TP ++
Sbjct: 1199 QHVIYLLDFCDAEVNAATLKGNNALHIACRGKHADLVELLLHKGANPAQRNQRGWTPRNS 1020

Query: 514  AAR 516
            A R
Sbjct: 1019 AGR 1011

 Score = 97.4 bits (241), Expect = 4e-20,   Method: Compositional matrix adjust.
 Identities = 76/265 (28%), Positives = 125/265 (47%), Gaps = 3/265 (1%)
 Frame = -1

Query: 150  TPLAVALQQGHENVVAHLINYGTKGKVRLPALHIAARNDDTRTAAVLLQNDPNPDVLSKT 209
            TPL +A + GH  VV+ L+        ++P + +  R++  R A                
Sbjct: 1739 TPLIIASRMGHLAVVSELL--------KVPGIDVNERDEKLRPA---------------- 1632

Query: 210  GFTPLHIAAHYENLNVAQLLLNRGASVN-FTPQNGITPLHIASRRGNVIMVRLLLDRGAQ 268
                L+ A    ++ + + L+  GA VN ++ +   TP H   +RG+  +   LL  GA 
Sbjct: 1631 ----LYFACMGNDIELVKQLVRYGARVNAYSTETWWTPFHACCKRGDPRIALYLLRHGAN 1464

Query: 269  IETRTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTK-NGLSPIHMAAQGDHLDCVRL 327
             E+RT D  TPL  A +N    ++ +L+  GA +         +P+H A Q  +++ ++ 
Sbjct: 1463 KESRTVDGKTPLVVACKNDKAEVALLLIRSGANVNVSCDITANTPVHFACQRPNIELLKR 1284

Query: 328  LLQYNAEIDDITLDHLTPLHVAAHCGHHRVAKVLLD-KGAKPNSRALNGFTPLHIACKKN 386
            L+ + A++D       T LHVA+  G  +    LLD   A+ N+  L G   LHIAC+  
Sbjct: 1283 LVLHGADVDKPNAKGHTALHVASVRGFKQHVIYLLDFCDAEVNAATLKGNNALHIACRGK 1104

Query: 387  HIRVMELLLKTGASIDAVTESGLTP 411
            H  ++ELLL  GA+     + G TP
Sbjct: 1103 HADLVELLLHKGANPAQRNQRGWTP 1029

 Score = 93.6 bits (231), Expect = 6e-19,   Method: Compositional matrix adjust.
 Identities = 76/238 (31%), Positives = 109/238 (45%), Gaps = 4/238 (1%)
 Frame = -1

Query: 442  ETPLHMAARAGHTEVXXXXXXXXXXXXXXXXXXXTP-LHCAARIGHTGMVKLLLENGASP 500
            ETPL +A+R GH  V                    P L+ A       +VK L+  GA  
Sbjct: 1742 ETPLIIASRMGHLAVVSELLKVPGIDVNERDEKLRPALYFACMGNDIELVKQLVRYGARV 1563

Query: 501  N-LATTAGHTPLHTAAREGHVDTALALLEKEASQACMTKKGFTPLHVAAKYGKVRLAELL 559
            N  +T    TP H   + G    AL LL   A++   T  G TPL VA K  K  +A LL
Sbjct: 1562 NAYSTETWWTPFHACCKRGDPRIALYLLRHGANKESRTVDGKTPLVVACKNDKAEVALLL 1383

Query: 560  LEHDAHPNAAGK-NGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQ 618
            +   A+ N +      TP+H A    N++++K L+  G     P   G+T LH+A+ +  
Sbjct: 1382 IRSGANVNVSCDITANTPVHFACQRPNIELLKRLVLHGADVDKPNAKGHTALHVASVRGF 1203

Query: 619  IEVARSLLQYG-GSANAESVQGVTPLHLAAQEGHTEMVALLLSKQANGNLGNKSGLTP 675
             +    LL +     NA +++G   LH+A +  H ++V LLL K AN    N+ G TP
Sbjct: 1202 KQHVIYLLDFCDAEVNAATLKGNNALHIACRGKHADLVELLLHKGANPAQRNQRGWTP 1029

 Score = 90.9 bits (224), Expect = 4e-18,   Method: Compositional matrix adjust.
 Identities = 80/251 (31%), Positives = 115/251 (45%), Gaps = 8/251 (3%)
 Frame = -1

Query: 53   LHLASKEGHVKMVVELLH-KEIILETTTKKGNTALHIAALAGQDEVVRELVNYGANVNAQ 111
            L +AS+ GH+ +V ELL    I +    +K   AL+ A +    E+V++LV YGA VNA 
Sbjct: 1733 LIIASRMGHLAVVSELLKVPGIDVNERDEKLRPALYFACMGNDIELVKQLVRYGARVNAY 1554

Query: 112  S-QKGFTPLYMAAQENHLEVVKFLLENGANQNVATEDGFTPLAVALQQGHENVVAHLINY 170
            S +  +TP +   +     +  +LL +GAN+   T DG TPL VA +     V   LI  
Sbjct: 1553 STETWWTPFHACCKRGDPRIALYLLRHGANKESRTVDGKTPLVVACKNDKAEVALLLIRS 1374

Query: 171  GTKGKVRLPA-----LHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAA-HYENLN 224
            G    V         +H A +  +      L+ +  + D  +  G T LH+A+      +
Sbjct: 1373 GANVNVSCDITANTPVHFACQRPNIELLKRLVLHGADVDKPNAKGHTALHVASVRGFKQH 1194

Query: 225  VAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETRTKDELTPLHCAA 284
            V  LL    A VN     G   LHIA R  +  +V LLL +GA    R +   TP     
Sbjct: 1193 VIYLLDFCDAEVNAATLKGNNALHIACRGKHADLVELLLHKGANPAQRNQRGWTP----- 1029

Query: 285  RNGHVRISEIL 295
            RN   R  E+L
Sbjct: 1028 RNSAGRCXEVL 996

 Score = 82.4 bits (202), Expect = 2e-15,   Method: Compositional matrix adjust.
 Identities = 81/280 (28%), Positives = 122/280 (43%), Gaps = 4/280 (1%)
 Frame = -1

Query: 344  TPLHVAAHCGHHRVAKVLLD-KGAKPNSRALNGFTPLHIACKKNHIRVMELLLKTGASID 402
            TPL +A+  GH  V   LL   G   N R       L+ AC  N I +++ L++ GA ++
Sbjct: 1739 TPLIIASRMGHLAVVSELLKVPGIDVNERDEKLRPALYFACMGNDIELVKQLVRYGARVN 1560

Query: 403  AV-TESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVXXXXX 461
            A  TE+  TP H     G   I   LL+ GA+     V  +TPL +A +    EV     
Sbjct: 1559 AYSTETWWTPFHACCKRGDPRIALYLLRHGANKESRTVDGKTPLVVACKNDKAEVAL--- 1389

Query: 462  XXXXXXXXXXXXXXTPLHCAARIGHTGMVKLLLENGASPNLAT-TAGHTPLHTAAREGHV 520
                                          LL+ +GA+ N++     +TP+H A +  ++
Sbjct: 1388 ------------------------------LLIRSGANVNVSCDITANTPVHFACQRPNI 1299

Query: 521  DTALALLEKEASQACMTKKGFTPLHVAAKYG-KVRLAELLLEHDAHPNAAGKNGLTPLHV 579
            +    L+   A       KG T LHVA+  G K  +  LL   DA  NAA   G   LH+
Sbjct: 1298 ELLKRLVLHGADVDKPNAKGHTALHVASVRGFKQHVIYLLDFCDAEVNAATLKGNNALHI 1119

Query: 580  AVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQI 619
            A    + D+V+LLL +G +P      G+TP + A +  ++
Sbjct: 1118 ACRGKHADLVELLLHKGANPAQRNQRGWTPRNSAGRCXEV 999

 Score = 82.0 bits (201), Expect = 2e-15,   Method: Compositional matrix adjust.
 Identities = 67/237 (28%), Positives = 109/237 (45%), Gaps = 4/237 (1%)
 Frame = -1

Query: 476  TPLHCAARIGHTGMVKLLLE-NGASPNLATTAGHTPLHTAAREGHVDTALALLEKEAS-Q 533
            TPL  A+R+GH  +V  LL+  G   N         L+ A     ++    L+   A   
Sbjct: 1739 TPLIIASRMGHLAVVSELLKVPGIDVNERDEKLRPALYFACMGNDIELVKQLVRYGARVN 1560

Query: 534  ACMTKKGFTPLHVAAKYGKVRLAELLLEHDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLL 593
            A  T+  +TP H   K G  R+A  LL H A+  +   +G TPL VA  ++  ++  LL+
Sbjct: 1559 AYSTETWWTPFHACCKRGDPRIALYLLRHGANKESRTVDGKTPLVVACKNDKAEVALLLI 1380

Query: 594  PRGGSPH-SPAWNGYTPLHIAAKQNQIEVARSLLQYGGSANAESVQGVTPLHLAAQEGHT 652
              G + + S      TP+H A ++  IE+ + L+ +G   +  + +G T LH+A+  G  
Sbjct: 1379 RSGANVNVSCDITANTPVHFACQRPNIELLKRLVLHGADVDKPNAKGHTALHVASVRGFK 1200

Query: 653  EMVALLLS-KQANGNLGNKSGLTPLHLVSQEGHVPVADVLIKHGVTVDATTRMGYTP 708
            + V  LL    A  N     G   LH+  +  H  + ++L+  G       + G+TP
Sbjct: 1199 QHVIYLLDFCDAEVNAATLKGNNALHIACRGKHADLVELLLHKGANPAQRNQRGWTP 1029

 Score = 68.6 bits (166), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 66/251 (26%), Positives = 120/251 (47%), Gaps = 11/251 (4%)
 Frame = -1

Query: 18   TSFLRAARSGNLDKALDHLR-NGVDINTCNQNGLNGLHLASKEGHVKMVVELL-HKEIIL 75
            T  + A+R G+L    + L+  G+D+N  ++     L+ A     +++V +L+ +   + 
Sbjct: 1739 TPLIIASRMGHLAVVSELLKVPGIDVNERDEKLRPALYFACMGNDIELVKQLVRYGARVN 1560

Query: 76   ETTTKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLL 135
              +T+   T  H     G   +   L+ +GAN  +++  G TPL +A + +  EV   L+
Sbjct: 1559 AYSTETWWTPFHACCKRGDPRIALYLLRHGANKESRTVDGKTPLVVACKNDKAEVALLLI 1380

Query: 136  ENGANQNVATE-DGFTPLAVALQQGHENVVAHLINYG-------TKGKVRLPALHIAARN 187
             +GAN NV+ +    TP+  A Q+ +  ++  L+ +G        KG     ALH+A+  
Sbjct: 1379 RSGANVNVSCDITANTPVHFACQRPNIELLKRLVLHGADVDKPNAKGHT---ALHVASVR 1209

Query: 188  DDTRTAAVLLQ-NDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFTPQNGITP 246
               +    LL   D   +  +  G   LHIA   ++ ++ +LLL++GA+     Q G TP
Sbjct: 1208 GFKQHVIYLLDFCDAEVNAATLKGNNALHIACRGKHADLVELLLHKGANPAQRNQRGWTP 1029

Query: 247  LHIASRRGNVI 257
             + A R   V+
Sbjct: 1028 RNSAGRCXEVL 996
>13462
          Length = 1388

 Score =  107 bits (268), Expect = 3e-23,   Method: Compositional matrix adjust.
 Identities = 83/248 (33%), Positives = 120/248 (48%), Gaps = 5/248 (2%)
 Frame = +3

Query: 536 MTKKGFTPLHVAAKYGKVRLAELLLEHDAHPNAAGKN-GLTPLHVAVHHNN--LDIVKLL 592
           +   G T L VA K  +  L  +LL+  A P+         PLH A HH+N  L IV +L
Sbjct: 63  LCGNGLTLLCVACKLNRADLVPVLLQRGALPDLPSLYLNKRPLHYASHHSNGNLGIVSML 242

Query: 593 LPRGGSPHSPAWNGYTPLHIAAKQNQIEVARSLLQYGGSANAESVQGVTPLHLAAQEGHT 652
           L  G  P+    +G T LH+A  ++ ++V R LL++GG      +   TPL  A      
Sbjct: 243 LAYGAQPNVQDEDGNTALHLACSESNVDVVRLLLEWGGDVAVADIDNETPLVRACLANSV 422

Query: 653 EMVALLLSKQANGNLGNKSGLTPLHLVSQEGHVPVADVLIKHGVTVDATTRMGYTPLHVA 712
           E+V LLL     G+  N S   PL +V +   +    +LI  G  V   T + +     A
Sbjct: 423 ELVDLLLHA---GSDPNHSHGRPLEIVVRAPSLESLKLLIGAGAQVTGNTYLSF-----A 578

Query: 713 SHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQA--AQQGHTDIVTLLLKNGASPNEVSSN 770
           S +  + ++K L  +  DVN   +LG + LH A  +Q+   D V LLL  G++PN V+  
Sbjct: 579 SEHNYLDMMKVLHNYGVDVNGTGRLGLTALHHACISQEATHDAVRLLLLWGSNPNLVTGT 758

Query: 771 GTTPLAIA 778
           G TPL  A
Sbjct: 759 GDTPLHFA 782

 Score = 91.3 bits (225), Expect = 3e-18,   Method: Compositional matrix adjust.
 Identities = 83/293 (28%), Positives = 132/293 (45%), Gaps = 38/293 (12%)
 Frame = +3

Query: 178 LPALHIAARNDDTRTAAVLLQNDPNPDVLS-KTGFTPLHIAAHYEN--LNVAQLLLNRGA 234
           L  L +A + +      VLLQ    PD+ S      PLH A+H+ N  L +  +LL  GA
Sbjct: 78  LTLLCVACKLNRADLVPVLLQRGALPDLPSLYLNKRPLHYASHHSNGNLGIVSMLLAYGA 257

Query: 235 SVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETRTKDELTPLHCAARNGHVRISEI 294
             N   ++G T LH+A    NV +VRLLL+ G  +     D  TPL  A     V + ++
Sbjct: 258 QPNVQDEDGNTALHLACSESNVDVVRLLLEWGGDVAVADIDNETPLVRACLANSVELVDL 437

Query: 295 LL--------DHGAPIQAKTK-----------------NGLSPIHMAAQGDHLDCVRLLL 329
           LL         HG P++   +                  G + +  A++ ++LD +++L 
Sbjct: 438 LLHAGSDPNHSHGRPLEIVVRAPSLESLKLLIGAGAQVTGNTYLSFASEHNYLDMMKVLH 617

Query: 330 QYNAEIDDITLDHLTPLHVA--AHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNH 387
            Y  +++      LT LH A  +    H   ++LL  G+ PN     G TPLH AC+   
Sbjct: 618 NYGVDVNGTGRLGLTALHHACISQEATHDAVRLLLLWGSNPNLVTGTGDTPLHFACQTFA 797

Query: 388 IRVMELLLKTGASIDAVTESGLTPLHVA--------SFMGHLPIVKNLLQRGA 432
           +  + LLL  GA ++ +  +  +PL  A        +   +L +++ LL  GA
Sbjct: 798 VSKVRLLLMYGADVNQIDGTHTSPLIAALTTRRQPQNDASYLDLIRLLLAAGA 956

 Score = 89.4 bits (220), Expect = 1e-17,   Method: Compositional matrix adjust.
 Identities = 88/285 (30%), Positives = 122/285 (42%), Gaps = 5/285 (1%)
 Frame = +3

Query: 364 KGAKPNSRALNGFTPLHIACKKNHIRVMELLLKTGASIDAVT-ESGLTPLHVASFM--GH 420
           +G   N    NG T L +ACK N   ++ +LL+ GA  D  +      PLH AS    G+
Sbjct: 42  QGDLVNGLCGNGLTLLCVACKLNRADLVPVLLQRGALPDLPSLYLNKRPLHYASHHSNGN 221

Query: 421 LPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVXXXXXXXXXXXXXXXXXXXTPLHC 480
           L IV  LL  GA PNV +    T LH+A    + +V                   TPL  
Sbjct: 222 LGIVSMLLAYGAQPNVQDEDGNTALHLACSESNVDVVRLLLEWGGDVAVADIDNETPLVR 401

Query: 481 AARIGHTGMVKLLLENGASPNLATTAGHTPLHTAAREGHVDTALALLEKEASQACMTKKG 540
           A       +V LLL  G+ PN    +   PL    R   +++ L LL    +Q      G
Sbjct: 402 ACLANSVELVDLLLHAGSDPN---HSHGRPLEIVVRAPSLES-LKLLIGAGAQV----TG 557

Query: 541 FTPLHVAAKYGKVRLAELLLEHDAHPNAAGKNGLTPLHVAV--HHNNLDIVKLLLPRGGS 598
            T L  A+++  + + ++L  +    N  G+ GLT LH A        D V+LLL  G +
Sbjct: 558 NTYLSFASEHNYLDMMKVLHNYGVDVNGTGRLGLTALHHACISQEATHDAVRLLLLWGSN 737

Query: 599 PHSPAWNGYTPLHIAAKQNQIEVARSLLQYGGSANAESVQGVTPL 643
           P+     G TPLH A +   +   R LL YG   N       +PL
Sbjct: 738 PNLVTGTGDTPLHFACQTFAVSKVRLLLMYGADVNQIDGTHTSPL 872

 Score = 84.7 bits (208), Expect = 3e-16,   Method: Compositional matrix adjust.
 Identities = 98/325 (30%), Positives = 145/325 (44%), Gaps = 18/325 (5%)
 Frame = +3

Query: 42  INTCNQNGLNGLHLASKEGHVKMVVELLHKEIILETTTKKGNT-ALHIAA--LAGQDEVV 98
           +N    NGL  L +A K     +V  LL +  + +  +   N   LH A+    G   +V
Sbjct: 54  VNGLCGNGLTLLCVACKLNRADLVPVLLQRGALPDLPSLYLNKRPLHYASHHSNGNLGIV 233

Query: 99  RELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQNVATEDGFTPLAVALQQ 158
             L+ YGA  N Q + G T L++A  E++++VV+ LLE G +  VA  D  TPL  A   
Sbjct: 234 SMLLAYGAQPNVQDEDGNTALHLACSESNVDVVRLLLEWGGDVAVADIDNETPLVRACLA 413

Query: 159 GHENVVAHLINYGTK-----GKVRLPALHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTP 213
               +V  L++ G+      G+     L I  R     +  +L+           TG T 
Sbjct: 414 NSVELVDLLLHAGSDPNHSHGR----PLEIVVRAPSLESLKLLIGAGAQ-----VTGNTY 566

Query: 214 LHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIA--SRRGNVIMVRLLLDRGAQIET 271
           L  A+ +  L++ ++L N G  VN T + G+T LH A  S+      VRLLL  G+    
Sbjct: 567 LSFASEHNYLDMMKVLHNYGVDVNGTGRLGLTALHHACISQEATHDAVRLLLLWGSNPNL 746

Query: 272 RTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAA------QGD--HLD 323
            T    TPLH A +   V    +LL +GA +        SP+  A       Q D  +LD
Sbjct: 747 VTGTGDTPLHFACQTFAVSKVRLLLMYGADVNQIDGTHTSPLIAALTTRRQPQNDASYLD 926

Query: 324 CVRLLLQYNAEIDDITLDHLTPLHV 348
            +RLLL   A +    L+ +  L V
Sbjct: 927 LIRLLLAAGARLSSAVLERIKVLIV 1001

 Score = 84.3 bits (207), Expect = 4e-16,   Method: Compositional matrix adjust.
 Identities = 91/312 (29%), Positives = 139/312 (44%), Gaps = 14/312 (4%)
 Frame = +3

Query: 299 GAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYNAEIDDITLDHLT--PLHVAAH--CGH 354
           G  +     NGL+ + +A + +  D V +LLQ  A + D+   +L   PLH A+H   G+
Sbjct: 45  GDLVNGLCGNGLTLLCVACKLNRADLVPVLLQRGA-LPDLPSLYLNKRPLHYASHHSNGN 221

Query: 355 HRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHIRVMELLLKTGASIDAVTESGLTPLHV 414
             +  +LL  GA+PN +  +G T LH+AC ++++ V+ LLL+ G  +        TPL  
Sbjct: 222 LGIVSMLLAYGAQPNVQDEDGNTALHLACSESNVDVVRLLLEWGGDVAVADIDNETPLVR 401

Query: 415 ASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVXXXXXXXXXXXXXXXXXX 474
           A     + +V  LL  G+ PN S+ +   PL +  RA   E                   
Sbjct: 402 ACLANSVELVDLLLHAGSDPNHSHGR---PLEIVVRAPSLE-----SLKLLIGAGAQVTG 557

Query: 475 XTPLHCAARIGHTGMVKLLLENGASPNLATTAGHTPLHTA--AREGHVDTALALLEKEAS 532
            T L  A+   +  M+K+L   G   N     G T LH A  ++E   D    LL   ++
Sbjct: 558 NTYLSFASEHNYLDMMKVLHNYGVDVNGTGRLGLTALHHACISQEATHDAVRLLLLWGSN 737

Query: 533 QACMTKKGFTPLHVAAKYGKVRLAELLLEHDAHPNAAGKNGLTPLHVAV--------HHN 584
              +T  G TPLH A +   V    LLL + A  N       +PL  A+          +
Sbjct: 738 PNLVTGTGDTPLHFACQTFAVSKVRLLLMYGADVNQIDGTHTSPLIAALTTRRQPQNDAS 917

Query: 585 NLDIVKLLLPRG 596
            LD+++LLL  G
Sbjct: 918 YLDLIRLLLAAG 953

 Score = 81.3 bits (199), Expect = 4e-15,   Method: Compositional matrix adjust.
 Identities = 85/304 (27%), Positives = 135/304 (44%), Gaps = 4/304 (1%)
 Frame = +3

Query: 232 RGASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGA--QIETRTKDELTPLHCAAR--NG 287
           +G  VN    NG+T L +A +     +V +LL RGA   + +   ++  PLH A+   NG
Sbjct: 42  QGDLVNGLCGNGLTLLCVACKLNRADLVPVLLQRGALPDLPSLYLNK-RPLHYASHHSNG 218

Query: 288 HVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYNAEIDDITLDHLTPLH 347
           ++ I  +LL +GA    + ++G + +H+A    ++D VRLLL++  ++    +D+ TPL 
Sbjct: 219 NLGIVSMLLAYGAQPNVQDEDGNTALHLACSESNVDVVRLLLEWGGDVAVADIDNETPLV 398

Query: 348 VAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHIRVMELLLKTGASIDAVTES 407
            A       +  +LL  G+ PN    +   PL I  +   +  ++LL+  GA +     +
Sbjct: 399 RACLANSVELVDLLLHAGSDPNH---SHGRPLEIVVRAPSLESLKLLIGAGAQV-----T 554

Query: 408 GLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVXXXXXXXXXXX 467
           G T L  AS   +L ++K L   G   N +     T LH A                   
Sbjct: 555 GNTYLSFASEHNYLDMMKVLHNYGVDVNGTGRLGLTALHHA------------------- 677

Query: 468 XXXXXXXXTPLHCAARIGHTGMVKLLLENGASPNLATTAGHTPLHTAAREGHVDTALALL 527
                       C ++      V+LLL  G++PNL T  G TPLH A +   V     LL
Sbjct: 678 ------------CISQEATHDAVRLLLLWGSNPNLVTGTGDTPLHFACQTFAVSKVRLLL 821

Query: 528 EKEA 531
              A
Sbjct: 822 MYGA 833

 Score = 70.5 bits (171), Expect = 5e-12,   Method: Compositional matrix adjust.
 Identities = 79/269 (29%), Positives = 124/269 (46%), Gaps = 14/269 (5%)
 Frame = +3

Query: 26  SGNLDKALDHLRNGVDINTCNQNGLNGLHLASKEGHVKMVVELLHKEIILETTTKKGNTA 85
           +GNL      L  G   N  +++G   LHLA  E +V +V  LL     +        T 
Sbjct: 213 NGNLGIVSMLLAYGAQPNVQDEDGNTALHLACSESNVDVVRLLLEWGGDVAVADIDNETP 392

Query: 86  LHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQNVAT 145
           L  A LA   E+V  L++ G++ N    +   PL +  +   LE +K L+  GA      
Sbjct: 393 LVRACLANSVELVDLLLHAGSDPNHSHGR---PLEIVVRAPSLESLKLLIGAGAQVT--- 554

Query: 146 EDGFTPLAVALQQGHENVVAHLINYGTK----GKVRLPALHIAARNDDTRTAAV--LLQN 199
             G T L+ A +  + +++  L NYG      G++ L ALH A  + +    AV  LL  
Sbjct: 555 --GNTYLSFASEHNYLDMMKVLHNYGVDVNGTGRLGLTALHHACISQEATHDAVRLLLLW 728

Query: 200 DPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPL--HIASRR---- 253
             NP++++ TG TPLH A     ++  +LLL  GA VN       +PL   + +RR    
Sbjct: 729 GSNPNLVTGTGDTPLHFACQTFAVSKVRLLLMYGADVNQIDGTHTSPLIAALTTRRQPQN 908

Query: 254 --GNVIMVRLLLDRGAQIETRTKDELTPL 280
               + ++RLLL  GA++ +   + +  L
Sbjct: 909 DASYLDLIRLLLAAGARLSSAVLERIKVL 995

 Score = 52.8 bits (125), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 41/130 (31%), Positives = 63/130 (48%), Gaps = 3/130 (2%)
 Frame = +3

Query: 664 NGNLGNKSGLTPLHLVSQEGHVPVADVLIKHGVTVDA-TTRMGYTPLHVASHY--GNIKL 720
           NG  GN  GLT L +  +     +  VL++ G   D  +  +   PLH ASH+  GN+ +
Sbjct: 57  NGLCGN--GLTLLCVACKLNRADLVPVLLQRGALPDLPSLYLNKRPLHYASHHSNGNLGI 230

Query: 721 VKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGASPNEVSSNGTTPLAIAKR 780
           V  LL + A  N + + G + LH A  + + D+V LLL+ G        +  TPL  A  
Sbjct: 231 VSMLLAYGAQPNVQDEDGNTALHLACSESNVDVVRLLLEWGGDVAVADIDNETPLVRACL 410

Query: 781 LGYISVTDVL 790
              + + D+L
Sbjct: 411 ANSVELVDLL 440
>02114
          Length = 1072

 Score = 95.9 bits (237), Expect = 1e-19,   Method: Compositional matrix adjust.
 Identities = 76/275 (27%), Positives = 134/275 (48%), Gaps = 8/275 (2%)
 Frame = +1

Query: 537 TKKGFTPLHVAAKYGKVRLAELLLEHDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRG 596
           T +G+TP H+AA  G+    + L  +    +A    G TPLH+A  H +   V+ LL  G
Sbjct: 193 TPRGWTPAHIAAIRGQEGCIQALSNNGVSMSAKDTRGSTPLHLACAHGHSFCVQTLLRCG 372

Query: 597 GSPHSPAWNGYTPLHIAAKQNQIEVARSLLQYGGSANAESVQGVTPLHLAAQEGHTEMVA 656
              +S     +T +H+++   ++   + L+++G   +     G TP HLAA EGH   + 
Sbjct: 373 VDVNSVDKTSWTSVHVSSYHGRLGCLQMLIKWGARYDDIDTNGNTPAHLAAMEGHLPCLK 552

Query: 657 LLLSKQA--NGNLG--NKSGLTPLHLVSQEGHVPVADVL--IKHGVTVDATTRMGYTPLH 710
            L+S +      LG  N  G TP  L  Q     + + +  ++H +           P H
Sbjct: 553 FLVSSEGCPEHTLGARNDHGETPRDLAQQFYKENILEYIDHVQHEMDHPEQAENLAFPAH 732

Query: 711 VASHYGNIKLVKFLLQHQ-ADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGASPNEVSS 769
           +A++ G +  ++ L+++   ++N +   G +  H+AA QGH +I+  L++ GA     + 
Sbjct: 733 MAAYNGELDHLRILVENGVVNINERDDKGNTLAHRAAGQGHLNILQWLVEMGADVEISNG 912

Query: 770 NGTTPLAIAKRLGYISVTDVLKVV-TDETSVVLVS 803
            G T   IA+R  +++   +L     +ETSVV+ S
Sbjct: 913 AGETARDIARRFAHLACVKLLGGEPEEETSVVVGS 1017

 Score = 81.3 bits (199), Expect(2) = 3e-18,   Method: Compositional matrix adjust.
 Identities = 69/262 (26%), Positives = 117/262 (44%), Gaps = 8/262 (3%)
 Frame = +1

Query: 405 TESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVXXXXXXXX 464
           T  G TP H+A+  G    ++ L   G S +  + +  TPLH+A   GH+          
Sbjct: 193 TPRGWTPAHIAAIRGQEGCIQALSNNGVSMSAKDTRGSTPLHLACAHGHSFCVQTLLRCG 372

Query: 465 XXXXXXXXXXXTPLHCAARIGHTGMVKLLLENGASPNLATTAGHTPLHTAAREGHVDTAL 524
                      T +H ++  G  G +++L++ GA  +   T G+TP H AA EGH+    
Sbjct: 373 VDVNSVDKTSWTSVHVSSYHGRLGCLQMLIKWGARYDDIDTNGNTPAHLAAMEGHLPCLK 552

Query: 525 ALLEKEA----SQACMTKKGFTPLHVAAKYGKVRLAELL--LEHDA-HPNAAGKNGLTPL 577
            L+  E     +       G TP  +A ++ K  + E +  ++H+  HP  A +N   P 
Sbjct: 553 FLVSSEGCPEHTLGARNDHGETPRDLAQQFYKENILEYIDHVQHEMDHPEQA-ENLAFPA 729

Query: 578 HVAVHHNNLDIVKLLLPRG-GSPHSPAWNGYTPLHIAAKQNQIEVARSLLQYGGSANAES 636
           H+A ++  LD +++L+  G  + +     G T  H AA Q  + + + L++ G      +
Sbjct: 730 HMAAYNGELDHLRILVENGVVNINERDDKGNTLAHRAAGQGHLNILQWLVEMGADVEISN 909

Query: 637 VQGVTPLHLAAQEGHTEMVALL 658
             G T   +A +  H   V LL
Sbjct: 910 GAGETARDIARRFAHLACVKLL 975

 Score = 30.8 bits (68), Expect(2) = 3e-18,   Method: Compositional matrix adjust.
 Identities = 17/54 (31%), Positives = 24/54 (44%), Gaps = 1/54 (1%)
 Frame = +3

Query: 359 KVLLDKGAKPNS-RALNGFTPLHIACKKNHIRVMELLLKTGASIDAVTESGLTP 411
           +V++  GA  N     + FTP+H AC    +  +  LL  GA        GL P
Sbjct: 51  EVMVKNGASINEVEDRDNFTPVHTACNIGALECLHWLLWHGADATVTHTXGLDP 212

 Score = 87.8 bits (216), Expect = 4e-17,   Method: Compositional matrix adjust.
 Identities = 73/261 (27%), Positives = 114/261 (43%), Gaps = 17/261 (6%)
 Frame = +1

Query: 210 GFTPLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQI 269
           G+TP HIAA        Q L N G S++     G TPLH+A   G+   V+ LL  G  +
Sbjct: 202 GWTPAHIAAIRGQEGCIQALSNNGVSMSAKDTRGSTPLHLACAHGHSFCVQTLLRCGVDV 381

Query: 270 ETRTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLL 329
            +  K   T +H ++ +G +   ++L+  GA       NG +P H+AA   HL C++ L+
Sbjct: 382 NSVDKTSWTSVHVSSYHGRLGCLQMLIKWGARYDDIDTNGNTPAHLAAMEGHLPCLKFLV 561

Query: 330 QYNAEIDDITLDHLTPLH-VAAHCGHHRVAKVLLDKGAKPN---------------SRAL 373
                          P H + A   H    + L  +  K N                +A 
Sbjct: 562 SSEG----------CPEHTLGARNDHGETPRDLAQQFYKENILEYIDHVQHEMDHPEQAE 711

Query: 374 NGFTPLHIACKKNHIRVMELLLKTG-ASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGA 432
           N   P H+A     +  + +L++ G  +I+   + G T  H A+  GHL I++ L++ GA
Sbjct: 712 NLAFPAHMAAYNGELDHLRILVENGVVNINERDDKGNTLAHRAAGQGHLNILQWLVEMGA 891

Query: 433 SPNVSNVKVETPLHMAARAGH 453
              +SN   ET   +A R  H
Sbjct: 892 DVEISNGAGETARDIARRFAH 954

 Score = 85.5 bits (210), Expect = 2e-16,   Method: Compositional matrix adjust.
 Identities = 73/264 (27%), Positives = 124/264 (46%), Gaps = 14/264 (5%)
 Frame = +1

Query: 79  TKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENG 138
           T +G T  HIAA+ GQ+  ++ L N G +++A+  +G TPL++A    H   V+ LL  G
Sbjct: 193 TPRGWTPAHIAAIRGQEGCIQALSNNGVSMSAKDTRGSTPLHLACAHGHSFCVQTLLRCG 372

Query: 139 ANQNVATEDGFTPLAVALQQGHENVVAHLINYG-------TKGKVRLPALHIAARNDDTR 191
            + N   +  +T + V+   G    +  LI +G       T G    PA H+AA      
Sbjct: 373 VDVNSVDKTSWTSVHVSSYHGRLGCLQMLIKWGARYDDIDTNGNT--PA-HLAAMEGHLP 543

Query: 192 TAAVLLQNDPNPD----VLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFTPQ--NGIT 245
               L+ ++  P+      +  G TP  +A  +   N+ + + +    ++   Q  N   
Sbjct: 544 CLKFLVSSEGCPEHTLGARNDHGETPRDLAQQFYKENILEYIDHVQHEMDHPEQAENLAF 723

Query: 246 PLHIASRRGNVIMVRLLLDRG-AQIETRTKDELTPLHCAARNGHVRISEILLDHGAPIQA 304
           P H+A+  G +  +R+L++ G   I  R     T  H AA  GH+ I + L++ GA ++ 
Sbjct: 724 PAHMAAYNGELDHLRILVENGVVNINERDDKGNTLAHRAAGQGHLNILQWLVEMGADVEI 903

Query: 305 KTKNGLSPIHMAAQGDHLDCVRLL 328
               G +   +A +  HL CV+LL
Sbjct: 904 SNGAGETARDIARRFAHLACVKLL 975

 Score = 85.1 bits (209), Expect = 2e-16,   Method: Compositional matrix adjust.
 Identities = 70/257 (27%), Positives = 116/257 (45%), Gaps = 8/257 (3%)
 Frame = +1

Query: 476 TPLHCAARIGHTGMVKLLLENGASPNLATTAGHTPLHTAAREGHVDTALALLEKEASQAC 535
           TP H AA  G  G ++ L  NG S +   T G TPLH A   GH      LL        
Sbjct: 208 TPAHIAAIRGQEGCIQALSNNGVSMSAKDTRGSTPLHLACAHGHSFCVQTLLRCGVDVNS 387

Query: 536 MTKKGFTPLHVAAKYGKVRLAELLLEHDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPR 595
           + K  +T +HV++ +G++   ++L++  A  +    NG TP H+A    +L  +K L+  
Sbjct: 388 VDKTSWTSVHVSSYHGRLGCLQMLIKWGARYDDIDTNGNTPAHLAAMEGHLPCLKFLVSS 567

Query: 596 GGSPHSPAW----NGYTPLHIAA---KQNQIEVARSLLQYGGSANAESVQGVTPLHLAAQ 648
            G P         +G TP  +A    K+N +E     +Q+      ++     P H+AA 
Sbjct: 568 EGCPEHTLGARNDHGETPRDLAQQFYKENILEYIDH-VQHEMDHPEQAENLAFPAHMAAY 744

Query: 649 EGHTEMVALLLSKQ-ANGNLGNKSGLTPLHLVSQEGHVPVADVLIKHGVTVDATTRMGYT 707
            G  + + +L+     N N  +  G T  H  + +GH+ +   L++ G  V+ +   G T
Sbjct: 745 NGELDHLRILVENGVVNINERDDKGNTLAHRAAGQGHLNILQWLVEMGADVEISNGAGET 924

Query: 708 PLHVASHYGNIKLVKFL 724
              +A  + ++  VK L
Sbjct: 925 ARDIARRFAHLACVKLL 975

 Score = 79.7 bits (195), Expect = 1e-14,   Method: Compositional matrix adjust.
 Identities = 69/237 (29%), Positives = 113/237 (47%), Gaps = 12/237 (5%)
 Frame = +1

Query: 38  NGVDINTCNQNGLNGLHLASKEGHVKMVVELLHKEIILETTTKKGNTALHIAALAGQDEV 97
           NGV ++  +  G   LHLA   GH   V  LL   + + +  K   T++H+++  G+   
Sbjct: 268 NGVSMSAKDTRGSTPLHLACAHGHSFCVQTLLRCGVDVNSVDKTSWTSVHVSSYHGRLGC 447

Query: 98  VRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGA----NQNVATEDGFTPLA 153
           ++ L+ +GA  +     G TP ++AA E HL  +KFL+ +            + G TP  
Sbjct: 448 LQMLIKWGARYDDIDTNGNTPAHLAAMEGHLPCLKFLVSSEGCPEHTLGARNDHGETPRD 627

Query: 154 VALQQGHENV------VAHLINYGTKGK-VRLPALHIAARNDDTRTAAVLLQND-PNPDV 205
           +A Q   EN+      V H +++  + + +  PA H+AA N +     +L++N   N + 
Sbjct: 628 LAQQFYKENILEYIDHVQHEMDHPEQAENLAFPA-HMAAYNGELDHLRILVENGVVNINE 804

Query: 206 LSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLL 262
               G T  H AA   +LN+ Q L+  GA V  +   G T   IA R  ++  V+LL
Sbjct: 805 RDDKGNTLAHRAAGQGHLNILQWLVEMGADVEISNGAGETARDIARRFAHLACVKLL 975

 Score = 78.2 bits (191), Expect = 3e-14,   Method: Compositional matrix adjust.
 Identities = 64/229 (27%), Positives = 97/229 (42%), Gaps = 40/229 (17%)
 Frame = +1

Query: 602 PAWNGYTPLHIAAKQNQIEVARSLLQYGGSANAESVQGVTPLHLAAQEGHTEMVALLLSK 661
           P   G+TP HIAA + Q    ++L   G S +A+  +G TPLHLA   GH+  V  LL  
Sbjct: 190 PTPRGWTPAHIAAIRGQEGCIQALSNNGVSMSAKDTRGSTPLHLACAHGHSFCVQTLLRC 369

Query: 662 QANGNLGNKSGLTPLHLVSQEGHVPVADVLIKHGVTVDATTRMGYTPLHVASHYGNIKLV 721
             + N  +K+  T +H+ S  G +    +LIK G   D     G TP H+A+  G++  +
Sbjct: 370 GVDVNSVDKTSWTSVHVSSYHGRLGCLQMLIKWGARYDDIDTNGNTPAHLAAMEGHLPCL 549

Query: 722 KFL---------------------------------------LQHQADVNAKTKLGYSPL 742
           KFL                                       +QH+ D   + +    P 
Sbjct: 550 KFLVSSEGCPEHTLGARNDHGETPRDLAQQFYKENILEYIDHVQHEMDHPEQAENLAFPA 729

Query: 743 HQAAQQGHTDIVTLLLKNG-ASPNEVSSNGTTPLAIAKRLGYISVTDVL 790
           H AA  G  D + +L++NG  + NE    G T    A   G++++   L
Sbjct: 730 HMAAYNGELDHLRILVENGVVNINERDDKGNTLAHRAAGQGHLNILQWL 876

 Score = 37.7 bits (86), Expect = 0.044,   Method: Compositional matrix adjust.
 Identities = 22/68 (32%), Positives = 32/68 (47%), Gaps = 1/68 (1%)
 Frame = +3

Query: 247 LHIASRRGNVIMVRLLLDRGAQI-ETRTKDELTPLHCAARNGHVRISEILLDHGAPIQAK 305
           +H A R  +V+ + +++  GA I E   +D  TP+H A   G +     LL HGA     
Sbjct: 12  IHDAVRHSDVLYLEVMVKNGASINEVEDRDNFTPVHTACNIGALECLHWLLWHGADATVT 191

Query: 306 TKNGLSPI 313
              GL P 
Sbjct: 192 HTXGLDPC 215

 Score = 33.1 bits (74), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 23/78 (29%), Positives = 40/78 (51%), Gaps = 1/78 (1%)
 Frame = +3

Query: 280 LHCAARNGHVRISEILLDHGAPI-QAKTKNGLSPIHMAAQGDHLDCVRLLLQYNAEIDDI 338
           +H A R+  V   E+++ +GA I + + ++  +P+H A     L+C+  LL + A   D 
Sbjct: 12  IHDAVRHSDVLYLEVMVKNGASINEVEDRDNFTPVHTACNIGALECLHWLLWHGA---DA 182

Query: 339 TLDHLTPLHVAAHCGHHR 356
           T+ H   L    H G+ R
Sbjct: 183 TVTHTXGLDPCPHRGNSR 236
>05924
          Length = 704

 Score = 94.4 bits (233), Expect = 3e-19,   Method: Compositional matrix adjust.
 Identities = 51/158 (32%), Positives = 88/158 (55%)
 Frame = +1

Query: 575 TPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQIEVARSLLQYGGSANA 634
           T LH AV   + D+V++L+  G + +S   +G T LH+A +     + + L+  G   N 
Sbjct: 70  TLLHEAVSMASEDLVQMLIKAGANANSTNQDGRTALHLACRGGYTNIVQILIAAGTDVNR 249

Query: 635 ESVQGVTPLHLAAQEGHTEMVALLLSKQANGNLGNKSGLTPLHLVSQEGHVPVADVLIKH 694
            +V G T LH+A   GHTE+V  L++  A+ N+ +  G +PL+  ++  +  +  VL+  
Sbjct: 250 RTVDGKTCLHVAVWRGHTEVVVKLVNAGADVNIPDSVGCSPLYWAARSNYTAILTVLVNA 429

Query: 695 GVTVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVN 732
           G  V+   +  +TPLH A H G++ +V++LL   A+ N
Sbjct: 430 GAKVNYRVKSKWTPLHAALHLGHMGVVRYLLLQGAETN 543

 Score = 93.6 bits (231), Expect = 7e-19,   Method: Compositional matrix adjust.
 Identities = 67/196 (34%), Positives = 98/196 (50%), Gaps = 8/196 (4%)
 Frame = +1

Query: 625 LLQYGGSANAESVQGVTPLHLAAQEGHTEMVALLLSKQANGNLGNKSGLTPLHLVSQEGH 684
           L++ G   NA      T LH A      ++V +L+   AN N  N+ G T LHL  + G+
Sbjct: 22  LVKGGVDVNARFWYDSTLLHEAVSMASEDLVQMLIKAGANANSTNQDGRTALHLACRGGY 201

Query: 685 VPVADVLIKHGVTVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQ 744
             +  +LI  G  V+  T  G T LHVA   G+ ++V  L+   ADVN    +G SPL+ 
Sbjct: 202 TNIVQILIAAGTDVNRRTVDGKTCLHVAVWRGHTEVVVKLVNAGADVNIPDSVGCSPLYW 381

Query: 745 AAQQGHTDIVTLLLKNGASPNEVSSNGTTPLAIAKRLGYISVTDVLKV--------VTDE 796
           AA+  +T I+T+L+  GA  N    +  TPL  A  LG++ V   L +        V D+
Sbjct: 382 AARSNYTAILTVLVNAGAKVNYRVKSKWTPLHAALHLGHMGVVRYLLLQGAETNITVQDK 561

Query: 797 TSVVLVSDKHRMSYPE 812
           T V L+ D   +S+ E
Sbjct: 562 TVVSLLMDNEHLSHKE 609

 Score = 92.8 bits (229), Expect = 1e-18,   Method: Compositional matrix adjust.
 Identities = 53/179 (29%), Positives = 97/179 (54%)
 Frame = +1

Query: 259 VRLLLDRGAQIETRTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQ 318
           V+ L+  G  +  R   + T LH A       + ++L+  GA   +  ++G + +H+A +
Sbjct: 13  VQRLVKGGVDVNARFWYDSTLLHEAVSMASEDLVQMLIKAGANANSTNQDGRTALHLACR 192

Query: 319 GDHLDCVRLLLQYNAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTP 378
           G + + V++L+    +++  T+D  T LHVA   GH  V   L++ GA  N     G +P
Sbjct: 193 GGYTNIVQILIAAGTDVNRRTVDGKTCLHVAVWRGHTEVVVKLVNAGADVNIPDSVGCSP 372

Query: 379 LHIACKKNHIRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVS 437
           L+ A + N+  ++ +L+  GA ++   +S  TPLH A  +GH+ +V+ LL +GA  N++
Sbjct: 373 LYWAARSNYTAILTVLVNAGAKVNYRVKSKWTPLHAALHLGHMGVVRYLLLQGAETNIT 549

 Score = 92.0 bits (227), Expect = 2e-18,   Method: Compositional matrix adjust.
 Identities = 54/158 (34%), Positives = 85/158 (53%)
 Frame = +1

Query: 212 TPLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIET 271
           T LH A    + ++ Q+L+  GA+ N T Q+G T LH+A R G   +V++L+  G  +  
Sbjct: 70  TLLHEAVSMASEDLVQMLIKAGANANSTNQDGRTALHLACRGGYTNIVQILIAAGTDVNR 249

Query: 272 RTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQY 331
           RT D  T LH A   GH  +   L++ GA +      G SP++ AA+ ++   + +L+  
Sbjct: 250 RTVDGKTCLHVAVWRGHTEVVVKLVNAGADVNIPDSVGCSPLYWAARSNYTAILTVLVNA 429

Query: 332 NAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPN 369
            A+++       TPLH A H GH  V + LL +GA+ N
Sbjct: 430 GAKVNYRVKSKWTPLHAALHLGHMGVVRYLLLQGAETN 543

 Score = 90.9 bits (224), Expect = 4e-18,   Method: Compositional matrix adjust.
 Identities = 51/141 (36%), Positives = 76/141 (53%)
 Frame = +1

Query: 36  LRNGVDINTCNQNGLNGLHLASKEGHVKMVVELLHKEIILETTTKKGNTALHIAALAGQD 95
           ++ G + N+ NQ+G   LHLA + G+  +V  L+     +   T  G T LH+A   G  
Sbjct: 124 IKAGANANSTNQDGRTALHLACRGGYTNIVQILIAAGTDVNRRTVDGKTCLHVAVWRGHT 303

Query: 96  EVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQNVATEDGFTPLAVA 155
           EVV +LVN GA+VN     G +PLY AA+ N+  ++  L+  GA  N   +  +TPL  A
Sbjct: 304 EVVVKLVNAGADVNIPDSVGCSPLYWAARSNYTAILTVLVNAGAKVNYRVKSKWTPLHAA 483

Query: 156 LQQGHENVVAHLINYGTKGKV 176
           L  GH  VV +L+  G +  +
Sbjct: 484 LHLGHMGVVRYLLLQGAETNI 546

 Score = 88.2 bits (217), Expect = 3e-17,   Method: Compositional matrix adjust.
 Identities = 57/166 (34%), Positives = 89/166 (53%), Gaps = 6/166 (3%)
 Frame = +1

Query: 83  NTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQN 142
           +T LH A     +++V+ L+  GAN N+ +Q G T L++A +  +  +V+ L+  G + N
Sbjct: 67  STLLHEAVSMASEDLVQMLIKAGANANSTNQDGRTALHLACRGGYTNIVQILIAAGTDVN 246

Query: 143 VATEDGFTPLAVALQQGHENVVAHLINYGTKGKVRLPA------LHIAARNDDTRTAAVL 196
             T DG T L VA+ +GH  VV  L+N G    V +P       L+ AAR++ T    VL
Sbjct: 247 RRTVDGKTCLHVAVWRGHTEVVVKLVNAG--ADVNIPDSVGCSPLYWAARSNYTAILTVL 420

Query: 197 LQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFTPQN 242
           +      +   K+ +TPLH A H  ++ V + LL +GA  N T Q+
Sbjct: 421 VNAGAKVNYRVKSKWTPLHAALHLGHMGVVRYLLLQGAETNITVQD 558

 Score = 84.7 bits (208), Expect = 3e-16,   Method: Compositional matrix adjust.
 Identities = 54/177 (30%), Positives = 87/177 (49%)
 Frame = +1

Query: 589 VKLLLPRGGSPHSPAWNGYTPLHIAAKQNQIEVARSLLQYGGSANAESVQGVTPLHLAAQ 648
           V+ L+  G   ++  W   T LH A      ++ + L++ G +AN+ +  G T LHLA +
Sbjct: 13  VQRLVKGGVDVNARFWYDSTLLHEAVSMASEDLVQMLIKAGANANSTNQDGRTALHLACR 192

Query: 649 EGHTEMVALLLSKQANGNLGNKSGLTPLHLVSQEGHVPVADVLIKHGVTVDATTRMGYTP 708
            G+T +V +L++   + N     G T LH+    GH  V   L+  G  V+    +G +P
Sbjct: 193 GGYTNIVQILIAAGTDVNRRTVDGKTCLHVAVWRGHTEVVVKLVNAGADVNIPDSVGCSP 372

Query: 709 LHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGASPN 765
           L+ A+      ++  L+   A VN + K  ++PLH A   GH  +V  LL  GA  N
Sbjct: 373 LYWAARSNYTAILTVLVNAGAKVNYRVKSKWTPLHAALHLGHMGVVRYLLLQGAETN 543

 Score = 84.3 bits (207), Expect = 4e-16,   Method: Compositional matrix adjust.
 Identities = 67/217 (30%), Positives = 100/217 (46%), Gaps = 6/217 (2%)
 Frame = +1

Query: 96  EVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQNVATEDGFTPLAVA 155
           + V+ LV  G +VNA+     T L+ A      ++V+ L++ GAN N   +DG T L +A
Sbjct: 7   KAVQRLVKGGVDVNARFWYDSTLLHEAVSMASEDLVQMLIKAGANANSTNQDGRTALHLA 186

Query: 156 LQQGHENVVAHLINYGTKGKVRLPALHIAARNDDTRTAAVLLQNDPNPDVLSKT--GFTP 213
            + G+ N+V  LI  GT                               DV  +T  G T 
Sbjct: 187 CRGGYTNIVQILIAAGT-------------------------------DVNRRTVDGKTC 273

Query: 214 LHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETRT 273
           LH+A    +  V   L+N GA VN     G +PL+ A+R     ++ +L++ GA++  R 
Sbjct: 274 LHVAVWRGHTEVVVKLVNAGADVNIPDSVGCSPLYWAARSNYTAILTVLVNAGAKVNYRV 453

Query: 274 KDELTPLHCAARNGHVRISEILLDHGA----PIQAKT 306
           K + TPLH A   GH+ +   LL  GA     +Q KT
Sbjct: 454 KSKWTPLHAALHLGHMGVVRYLLLQGAETNITVQDKT 564

 Score = 80.1 bits (196), Expect = 8e-15,   Method: Compositional matrix adjust.
 Identities = 54/173 (31%), Positives = 86/173 (49%)
 Frame = +1

Query: 227 QLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETRTKDELTPLHCAARN 286
           Q L+  G  VN       T LH A    +  +V++L+  GA   +  +D  T LH A R 
Sbjct: 16  QRLVKGGVDVNARFWYDSTLLHEAVSMASEDLVQMLIKAGANANSTNQDGRTALHLACRG 195

Query: 287 GHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYNAEIDDITLDHLTPL 346
           G+  I +IL+  G  +  +T +G + +H+A    H + V  L+   A+++       +PL
Sbjct: 196 GYTNIVQILIAAGTDVNRRTVDGKTCLHVAVWRGHTEVVVKLVNAGADVNIPDSVGCSPL 375

Query: 347 HVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHIRVMELLLKTGA 399
           + AA   +  +  VL++ GAK N R  + +TPLH A    H+ V+  LL  GA
Sbjct: 376 YWAARSNYTAILTVLVNAGAKVNYRVKSKWTPLHAALHLGHMGVVRYLLLQGA 534

 Score = 79.7 bits (195), Expect = 1e-14,   Method: Compositional matrix adjust.
 Identities = 54/177 (30%), Positives = 83/177 (46%)
 Frame = +1

Query: 355 HRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHIRVMELLLKTGASIDAVTESGLTPLHV 414
           H+  + L+  G   N+R     T LH A       ++++L+K GA+ ++  + G T LH+
Sbjct: 4   HKAVQRLVKGGVDVNARFWYDSTLLHEAVSMASEDLVQMLIKAGANANSTNQDGRTALHL 183

Query: 415 ASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVXXXXXXXXXXXXXXXXXX 474
           A   G+  IV+ L+  G   N   V  +T LH+A   GHTEV                  
Sbjct: 184 ACRGGYTNIVQILIAAGTDVNRRTVDGKTCLHVAVWRGHTEVVVKLVNAGADVNIPDSVG 363

Query: 475 XTPLHCAARIGHTGMVKLLLENGASPNLATTAGHTPLHTAAREGHVDTALALLEKEA 531
            +PL+ AAR  +T ++ +L+  GA  N    +  TPLH A   GH+     LL + A
Sbjct: 364 CSPLYWAARSNYTAILTVLVNAGAKVNYRVKSKWTPLHAALHLGHMGVVRYLLLQGA 534

 Score = 75.5 bits (184), Expect = 2e-13,   Method: Compositional matrix adjust.
 Identities = 48/162 (29%), Positives = 79/162 (48%)
 Frame = +1

Query: 542 TPLHVAAKYGKVRLAELLLEHDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHS 601
           T LH A       L ++L++  A+ N+  ++G T LH+A      +IV++L+  G   + 
Sbjct: 70  TLLHEAVSMASEDLVQMLIKAGANANSTNQDGRTALHLACRGGYTNIVQILIAAGTDVNR 249

Query: 602 PAWNGYTPLHIAAKQNQIEVARSLLQYGGSANAESVQGVTPLHLAAQEGHTEMVALLLSK 661
              +G T LH+A  +   EV   L+  G   N     G +PL+ AA+  +T ++ +L++ 
Sbjct: 250 RTVDGKTCLHVAVWRGHTEVVVKLVNAGADVNIPDSVGCSPLYWAARSNYTAILTVLVNA 429

Query: 662 QANGNLGNKSGLTPLHLVSQEGHVPVADVLIKHGVTVDATTR 703
            A  N   KS  TPLH     GH+ V   L+  G   + T +
Sbjct: 430 GAKVNYRVKSKWTPLHAALHLGHMGVVRYLLLQGAETNITVQ 555

 Score = 75.5 bits (184), Expect = 2e-13,   Method: Compositional matrix adjust.
 Identities = 44/142 (30%), Positives = 75/142 (52%)
 Frame = +1

Query: 195 VLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIASRRG 254
           +L++   N +  ++ G T LH+A      N+ Q+L+  G  VN    +G T LH+A  RG
Sbjct: 118 MLIKAGANANSTNQDGRTALHLACRGGYTNIVQILIAAGTDVNRRTVDGKTCLHVAVWRG 297

Query: 255 NVIMVRLLLDRGAQIETRTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIH 314
           +  +V  L++ GA +        +PL+ AAR+ +  I  +L++ GA +  + K+  +P+H
Sbjct: 298 HTEVVVKLVNAGADVNIPDSVGCSPLYWAARSNYTAILTVLVNAGAKVNYRVKSKWTPLH 477

Query: 315 MAAQGDHLDCVRLLLQYNAEID 336
            A    H+  VR LL   AE +
Sbjct: 478 AALHLGHMGVVRYLLLQGAETN 543

 Score = 71.2 bits (173), Expect = 4e-12,   Method: Compositional matrix adjust.
 Identities = 46/162 (28%), Positives = 76/162 (46%)
 Frame = +1

Query: 295 LLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYNAEIDDITLDHLTPLHVAAHCGH 354
           L+  G  + A+     + +H A      D V++L++  A  +    D  T LH+A   G+
Sbjct: 22  LVKGGVDVNARFWYDSTLLHEAVSMASEDLVQMLIKAGANANSTNQDGRTALHLACRGGY 201

Query: 355 HRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHIRVMELLLKTGASIDAVTESGLTPLHV 414
             + ++L+  G   N R ++G T LH+A  + H  V+  L+  GA ++     G +PL+ 
Sbjct: 202 TNIVQILIAAGTDVNRRTVDGKTCLHVAVWRGHTEVVVKLVNAGADVNIPDSVGCSPLYW 381

Query: 415 ASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEV 456
           A+   +  I+  L+  GA  N       TPLH A   GH  V
Sbjct: 382 AARSNYTAILTVLVNAGAKVNYRVKSKWTPLHAALHLGHMGV 507

 Score = 69.3 bits (168), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 55/208 (26%), Positives = 89/208 (42%)
 Frame = +1

Query: 389 RVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMA 448
           + ++ L+K G  ++A      T LH A  M    +V+ L++ GA+ N +N    T LH+A
Sbjct: 7   KAVQRLVKGGVDVNARFWYDSTLLHEAVSMASEDLVQMLIKAGANANSTNQDGRTALHLA 186

Query: 449 ARAGHTEVXXXXXXXXXXXXXXXXXXXTPLHCAARIGHTGMVKLLLENGASPNLATTAGH 508
                                             R G+T +V++L+  G   N  T  G 
Sbjct: 187 C---------------------------------RGGYTNIVQILIAAGTDVNRRTVDGK 267

Query: 509 TPLHTAAREGHVDTALALLEKEASQACMTKKGFTPLHVAAKYGKVRLAELLLEHDAHPNA 568
           T LH A   GH +  + L+   A        G +PL+ AA+     +  +L+   A  N 
Sbjct: 268 TCLHVAVWRGHTEVVVKLVNAGADVNIPDSVGCSPLYWAARSNYTAILTVLVNAGAKVNY 447

Query: 569 AGKNGLTPLHVAVHHNNLDIVKLLLPRG 596
             K+  TPLH A+H  ++ +V+ LL +G
Sbjct: 448 RVKSKWTPLHAALHLGHMGVVRYLLLQG 531

 Score = 67.0 bits (162), Expect = 7e-11,   Method: Compositional matrix adjust.
 Identities = 51/178 (28%), Positives = 78/178 (43%)
 Frame = +1

Query: 490 VKLLLENGASPNLATTAGHTPLHTAAREGHVDTALALLEKEASQACMTKKGFTPLHVAAK 549
           V+ L++ G   N       T LH A      D    L++  A+     + G T LH+A +
Sbjct: 13  VQRLVKGGVDVNARFWYDSTLLHEAVSMASEDLVQMLIKAGANANSTNQDGRTALHLACR 192

Query: 550 YGKVRLAELLLEHDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTP 609
            G   + ++L+      N    +G T LHVAV   + ++V  L+  G   + P   G +P
Sbjct: 193 GGYTNIVQILIAAGTDVNRRTVDGKTCLHVAVWRGHTEVVVKLVNAGADVNIPDSVGCSP 372

Query: 610 LHIAAKQNQIEVARSLLQYGGSANAESVQGVTPLHLAAQEGHTEMVALLLSKQANGNL 667
           L+ AA+ N   +   L+  G   N       TPLH A   GH  +V  LL + A  N+
Sbjct: 373 LYWAARSNYTAILTVLVNAGAKVNYRVKSKWTPLHAALHLGHMGVVRYLLLQGAETNI 546

 Score = 64.7 bits (156), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 41/133 (30%), Positives = 67/133 (50%)
 Frame = +1

Query: 15  DAATSFLRAARSGNLDKALDHLRNGVDINTCNQNGLNGLHLASKEGHVKMVVELLHKEII 74
           D  T+   A R G  +     +  G D+N    +G   LH+A   GH ++VV+L++    
Sbjct: 160 DGRTALHLACRGGYTNIVQILIAAGTDVNRRTVDGKTCLHVAVWRGHTEVVVKLVNAGAD 339

Query: 75  LETTTKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFL 134
           +      G + L+ AA +    ++  LVN GA VN + +  +TPL+ A    H+ VV++L
Sbjct: 340 VNIPDSVGCSPLYWAARSNYTAILTVLVNAGAKVNYRVKSKWTPLHAALHLGHMGVVRYL 519

Query: 135 LENGANQNVATED 147
           L  GA  N+  +D
Sbjct: 520 LLQGAETNITVQD 558

 Score = 62.8 bits (151), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 52/176 (29%), Positives = 75/176 (42%)
 Frame = +1

Query: 476 TPLHCAARIGHTGMVKLLLENGASPNLATTAGHTPLHTAAREGHVDTALALLEKEASQAC 535
           T LH A  +    +V++L++ GA+ N     G T LH A R G+ +    L+        
Sbjct: 70  TLLHEAVSMASEDLVQMLIKAGANANSTNQDGRTALHLACRGGYTNIVQILIAAGTDVNR 249

Query: 536 MTKKGFTPLHVAAKYGKVRLAELLLEHDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPR 595
            T  G T LHVA   G   +   L+   A  N     G +PL+ A   N   I+ +L+  
Sbjct: 250 RTVDGKTCLHVAVWRGHTEVVVKLVNAGADVNIPDSVGCSPLYWAARSNYTAILTVLVNA 429

Query: 596 GGSPHSPAWNGYTPLHIAAKQNQIEVARSLLQYGGSANAESVQGVTPLHLAAQEGH 651
           G   +    + +TPLH A     + V R LL  G   N  +VQ  T + L     H
Sbjct: 430 GAKVNYRVKSKWTPLHAALHLGHMGVVRYLLLQGAETNI-TVQDKTVVSLLMDNEH 594
>08473
          Length = 942

 Score = 75.1 bits (183), Expect = 3e-13,   Method: Compositional matrix adjust.
 Identities = 46/127 (36%), Positives = 66/127 (51%)
 Frame = -1

Query: 178 LPALHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVN 237
           + ALH A           LLQ   NP  +   G TPL  AAH   +++ +LL+++GA+VN
Sbjct: 915 MTALHHACAGLHYGCVHALLQGGANPTCMEMGGKTPLFYAAHRGEISICKLLVDKGANVN 736

Query: 238 FTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETRTKDELTPLHCAARNGHVRISEILLD 297
              +  ITPL +A+R GN   V  LL RGA   T  ++    L+ A   GH  + E+  +
Sbjct: 735 AADKMLITPLMVAAREGNREAVEFLLKRGANPNTADREGHLALYYAMAAGHPELREVFAN 556

Query: 298 HGAPIQA 304
             AP+QA
Sbjct: 555 --APLQA 541

 Score = 71.2 bits (173), Expect = 4e-12,   Method: Compositional matrix adjust.
 Identities = 42/123 (34%), Positives = 67/123 (54%)
 Frame = -1

Query: 334 EIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHIRVMEL 393
           ++D    + +T LH A    H+     LL  GA P    + G TPL  A  +  I + +L
Sbjct: 942 DVDMRDSNDMTALHHACAGLHYGCVHALLQGGANPTCMEMGGKTPLFYAAHRGEISICKL 763

Query: 394 LLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGH 453
           L+  GA+++A  +  +TPL VA+  G+   V+ LL+RGA+PN ++ +    L+ A  AGH
Sbjct: 762 LVDKGANVNAADKMLITPLMVAAREGNREAVEFLLKRGANPNTADREGHLALYYAMAAGH 583

Query: 454 TEV 456
            E+
Sbjct: 582 PEL 574

 Score = 68.9 bits (167), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 44/120 (36%), Positives = 60/120 (50%)
 Frame = -1

Query: 41  DINTCNQNGLNGLHLASKEGHVKMVVELLHKEIILETTTKKGNTALHIAALAGQDEVVRE 100
           D++  + N +  LH A    H   V  LL            G T L  AA  G+  + + 
Sbjct: 942 DVDMRDSNDMTALHHACAGLHYGCVHALLQGGANPTCMEMGGKTPLFYAAHRGEISICKL 763

Query: 101 LVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQNVATEDGFTPLAVALQQGH 160
           LV+ GANVNA  +   TPL +AA+E + E V+FLL+ GAN N A  +G   L  A+  GH
Sbjct: 762 LVDKGANVNAADKMLITPLMVAAREGNREAVEFLLKRGANPNTADREGHLALYYAMAAGH 583

 Score = 66.6 bits (161), Expect = 8e-11,   Method: Compositional matrix adjust.
 Identities = 40/119 (33%), Positives = 59/119 (49%)
 Frame = -1

Query: 302 IQAKTKNGLSPIHMAAQGDHLDCVRLLLQYNAEIDDITLDHLTPLHVAAHCGHHRVAKVL 361
           +  +  N ++ +H A  G H  CV  LLQ  A    + +   TPL  AAH G   + K+L
Sbjct: 939 VDMRDSNDMTALHHACAGLHYGCVHALLQGGANPTCMEMGGKTPLFYAAHRGEISICKLL 760

Query: 362 LDKGAKPNSRALNGFTPLHIACKKNHIRVMELLLKTGASIDAVTESGLTPLHVASFMGH 420
           +DKGA  N+      TPL +A ++ +   +E LLK GA+ +     G   L+ A   GH
Sbjct: 759 VDKGANVNAADKMLITPLMVAAREGNREAVEFLLKRGANPNTADREGHLALYYAMAAGH 583

 Score = 65.5 bits (158), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 40/105 (38%), Positives = 57/105 (54%)
 Frame = -1

Query: 509 TPLHTAAREGHVDTALALLEKEASQACMTKKGFTPLHVAAKYGKVRLAELLLEHDAHPNA 568
           T LH A    H     ALL+  A+  CM   G TPL  AA  G++ + +LL++  A+ NA
Sbjct: 912 TALHHACAGLHYGCVHALLQGGANPTCMEMGGKTPLFYAAHRGEISICKLLVDKGANVNA 733

Query: 569 AGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIA 613
           A K  +TPL VA    N + V+ LL RG +P++    G+  L+ A
Sbjct: 732 ADKMLITPLMVAAREGNREAVEFLLKRGANPNTADREGHLALYYA 598

 Score = 64.7 bits (156), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 39/118 (33%), Positives = 56/118 (47%)
 Frame = -1

Query: 673 LTPLHLVSQEGHVPVADVLIKHGVTVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVN 732
           +T LH      H      L++ G         G TPL  A+H G I + K L+   A+VN
Sbjct: 915 MTALHHACAGLHYGCVHALLQGGANPTCMEMGGKTPLFYAAHRGEISICKLLVDKGANVN 736

Query: 733 AKTKLGYSPLHQAAQQGHTDIVTLLLKNGASPNEVSSNGTTPLAIAKRLGYISVTDVL 790
           A  K+  +PL  AA++G+ + V  LLK GA+PN     G   L  A   G+  + +V 
Sbjct: 735 AADKMLITPLMVAAREGNREAVEFLLKRGANPNTADREGHLALYYAMAAGHPELREVF 562

 Score = 63.5 bits (153), Expect = 7e-10,   Method: Compositional matrix adjust.
 Identities = 40/120 (33%), Positives = 59/120 (49%)
 Frame = -1

Query: 572 NGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQIEVARSLLQYGGS 631
           N +T LH A    +   V  LL  G +P      G TPL  AA + +I + + L+  G +
Sbjct: 921 NDMTALHHACAGLHYGCVHALLQGGANPTCMEMGGKTPLFYAAHRGEISICKLLVDKGAN 742

Query: 632 ANAESVQGVTPLHLAAQEGHTEMVALLLSKQANGNLGNKSGLTPLHLVSQEGHVPVADVL 691
            NA     +TPL +AA+EG+ E V  LL + AN N  ++ G   L+     GH  + +V 
Sbjct: 741 VNAADKMLITPLMVAAREGNREAVEFLLKRGANPNTADREGHLALYYAMAAGHPELREVF 562

 Score = 62.0 bits (149), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 38/114 (33%), Positives = 56/114 (49%)
 Frame = -1

Query: 640 VTPLHLAAQEGHTEMVALLLSKQANGNLGNKSGLTPLHLVSQEGHVPVADVLIKHGVTVD 699
           +T LH A    H   V  LL   AN       G TPL   +  G + +  +L+  G  V+
Sbjct: 915 MTALHHACAGLHYGCVHALLQGGANPTCMEMGGKTPLFYAAHRGEISICKLLVDKGANVN 736

Query: 700 ATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDI 753
           A  +M  TPL VA+  GN + V+FLL+  A+ N   + G+  L+ A   GH ++
Sbjct: 735 AADKMLITPLMVAAREGNREAVEFLLKRGANPNTADREGHLALYYAMAAGHPEL 574

 Score = 61.6 bits (148), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 43/134 (32%), Positives = 64/134 (47%)
 Frame = -1

Query: 476 TPLHCAARIGHTGMVKLLLENGASPNLATTAGHTPLHTAAREGHVDTALALLEKEASQAC 535
           T LH A    H G V  LL+ GA+P      G TPL  AA  G +     L++K A+   
Sbjct: 912 TALHHACAGLHYGCVHALLQGGANPTCMEMGGKTPLFYAAHRGEISICKLLVDKGANVNA 733

Query: 536 MTKKGFTPLHVAAKYGKVRLAELLLEHDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPR 595
             K   TPL VAA+ G     E LL+  A+PN A + G   L+ A+   + ++ ++    
Sbjct: 732 ADKMLITPLMVAAREGNREAVEFLLKRGANPNTADREGHLALYYAMAAGHPELREVF--- 562

Query: 596 GGSPHSPAWNGYTP 609
             +P   +W+  +P
Sbjct: 561 ANAPLQASWDLRSP 520

 Score = 57.8 bits (138), Expect = 4e-08,   Method: Compositional matrix adjust.
 Identities = 37/118 (31%), Positives = 52/118 (44%)
 Frame = -1

Query: 204 DVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLLL 263
           D+      T LH A    +      LL  GA+       G TPL  A+ RG + + +LL+
Sbjct: 936 DMRDSNDMTALHHACAGLHYGCVHALLQGGANPTCMEMGGKTPLFYAAHRGEISICKLLV 757

Query: 264 DRGAQIETRTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDH 321
           D+GA +    K  +TPL  AAR G+    E LL  GA      + G   ++ A    H
Sbjct: 756 DKGANVNAADKMLITPLMVAAREGNREAVEFLLKRGANPNTADREGHLALYYAMAAGH 583

 Score = 56.6 bits (135), Expect = 9e-08,   Method: Compositional matrix adjust.
 Identities = 37/116 (31%), Positives = 55/116 (47%)
 Frame = -1

Query: 605 NGYTPLHIAAKQNQIEVARSLLQYGGSANAESVQGVTPLHLAAQEGHTEMVALLLSKQAN 664
           N  T LH A          +LLQ G +     + G TPL  AA  G   +  LL+ K AN
Sbjct: 921 NDMTALHHACAGLHYGCVHALLQGGANPTCMEMGGKTPLFYAAHRGEISICKLLVDKGAN 742

Query: 665 GNLGNKSGLTPLHLVSQEGHVPVADVLIKHGVTVDATTRMGYTPLHVASHYGNIKL 720
            N  +K  +TPL + ++EG+    + L+K G   +   R G+  L+ A   G+ +L
Sbjct: 741 VNAADKMLITPLMVAAREGNREAVEFLLKRGANPNTADREGHLALYYAMAAGHPEL 574

 Score = 53.9 bits (128), Expect = 5e-07,   Method: Compositional matrix adjust.
 Identities = 32/88 (36%), Positives = 43/88 (48%)
 Frame = -1

Query: 84  TALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQNV 143
           TALH A        V  L+  GAN       G TPL+ AA    + + K L++ GAN N 
Sbjct: 912 TALHHACAGLHYGCVHALLQGGANPTCMEMGGKTPLFYAAHRGEISICKLLVDKGANVNA 733

Query: 144 ATEDGFTPLAVALQQGHENVVAHLINYG 171
           A +   TPL VA ++G+   V  L+  G
Sbjct: 732 ADKMLITPLMVAAREGNREAVEFLLKRG 649

 Score = 52.4 bits (124), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 35/126 (27%), Positives = 55/126 (43%)
 Frame = -1

Query: 269 IETRTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLL 328
           ++ R  +++T LH A    H      LL  GA        G +P+  AA    +   +LL
Sbjct: 939 VDMRDSNDMTALHHACAGLHYGCVHALLQGGANPTCMEMGGKTPLFYAAHRGEISICKLL 760

Query: 329 LQYNAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHI 388
           +   A ++      +TPL VAA  G+    + LL +GA PN+    G   L+ A    H 
Sbjct: 759 VDKGANVNAADKMLITPLMVAAREGNREAVEFLLKRGANPNTADREGHLALYYAMAAGHP 580

Query: 389 RVMELL 394
            + E+ 
Sbjct: 579 ELREVF 562

 Score = 50.8 bits (120), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 35/114 (30%), Positives = 51/114 (44%)
 Frame = -1

Query: 541 FTPLHVAAKYGKVRLAELLLEHDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPH 600
            T LH A           LL+  A+P      G TPL  A H   + I KLL+ +G + +
Sbjct: 915 MTALHHACAGLHYGCVHALLQGGANPTCMEMGGKTPLFYAAHRGEISICKLLVDKGANVN 736

Query: 601 SPAWNGYTPLHIAAKQNQIEVARSLLQYGGSANAESVQGVTPLHLAAQEGHTEM 654
           +      TPL +AA++   E    LL+ G + N    +G   L+ A   GH E+
Sbjct: 735 AADKMLITPLMVAAREGNREAVEFLLKRGANPNTADREGHLALYYAMAAGHPEL 574

 Score = 43.5 bits (101), Expect = 8e-04,   Method: Compositional matrix adjust.
 Identities = 31/115 (26%), Positives = 49/115 (42%), Gaps = 4/115 (3%)
 Frame = -1

Query: 107 NVNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQNVATEDGFTPLAVALQQGHENVVAH 166
           +V+ +     T L+ A    H   V  LL+ GAN       G TPL  A  +G  ++   
Sbjct: 942 DVDMRDSNDMTALHHACAGLHYGCVHALLQGGANPTCMEMGGKTPLFYAAHRGEISICKL 763

Query: 167 LINYGTK----GKVRLPALHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIA 217
           L++ G       K+ +  L +AAR  +      LL+   NP+   + G   L+ A
Sbjct: 762 LVDKGANVNAADKMLITPLMVAAREGNREAVEFLLKRGANPNTADREGHLALYYA 598
>25470
          Length = 400

 Score = 72.4 bits (176), Expect = 1e-12,   Method: Compositional matrix adjust.
 Identities = 38/101 (37%), Positives = 60/101 (59%)
 Frame = -3

Query: 678 LVSQEGHVPVADVLIKHGVTVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKL 737
           L +  G   V + L+++G  V A    G  PLH A  +G+ ++V+ LL+H AD NA+   
Sbjct: 380 LAAGFGRKDVVEHLLENGANVHARDDGGLIPLHNACSFGHAEVVQLLLRHGADPNARDNW 201

Query: 738 GYSPLHQAAQQGHTDIVTLLLKNGASPNEVSSNGTTPLAIA 778
            Y+PLH+AA +G  D+  +LL+  A PN  +++G T L +A
Sbjct: 200 NYTPLHEAAIKGKIDVCIVLLQQCADPNIRNTDGKTALDLA 78

 Score = 66.6 bits (161), Expect = 9e-11,   Method: Compositional matrix adjust.
 Identities = 39/101 (38%), Positives = 55/101 (54%)
 Frame = -3

Query: 348 VAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHIRVMELLLKTGASIDAVTES 407
           +AA  G   V + LL+ GA  ++R   G  PLH AC   H  V++LLL+ GA  +A    
Sbjct: 380 LAAGFGRKDVVEHLLENGANVHARDDGGLIPLHNACSFGHAEVVQLLLRHGADPNARDNW 201

Query: 408 GLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMA 448
             TPLH A+  G + +   LLQ+ A PN+ N   +T L +A
Sbjct: 200 NYTPLHEAAIKGKIDVCIVLLQQCADPNIRNTDGKTALDLA 78

 Score = 63.2 bits (152), Expect = 9e-10,   Method: Compositional matrix adjust.
 Identities = 41/102 (40%), Positives = 58/102 (56%), Gaps = 1/102 (0%)
 Frame = -3

Query: 546 VAAKYGKVRLAELLLEHDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHS-PAW 604
           +AA +G+  + E LLE+ A+ +A    GL PLH A    + ++V+LLL  G  P++   W
Sbjct: 380 LAAGFGRKDVVEHLLENGANVHARDDGGLIPLHNACSFGHAEVVQLLLRHGADPNARDNW 201

Query: 605 NGYTPLHIAAKQNQIEVARSLLQYGGSANAESVQGVTPLHLA 646
           N YTPLH AA + +I+V   LLQ     N  +  G T L LA
Sbjct: 200 N-YTPLHEAAIKGKIDVCIVLLQQCADPNIRNTDGKTALDLA 78

 Score = 60.5 bits (145), Expect = 6e-09,   Method: Compositional matrix adjust.
 Identities = 38/101 (37%), Positives = 50/101 (49%)
 Frame = -3

Query: 645 LAAQEGHTEMVALLLSKQANGNLGNKSGLTPLHLVSQEGHVPVADVLIKHGVTVDATTRM 704
           LAA  G  ++V  LL   AN +  +  GL PLH     GH  V  +L++HG   +A    
Sbjct: 380 LAAGFGRKDVVEHLLENGANVHARDDGGLIPLHNACSFGHAEVVQLLLRHGADPNARDNW 201

Query: 705 GYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQA 745
            YTPLH A+  G I +   LLQ  AD N +   G + L  A
Sbjct: 200 NYTPLHEAAIKGKIDVCIVLLQQCADPNIRNTDGKTALDLA 78

 Score = 57.4 bits (137), Expect = 5e-08,   Method: Compositional matrix adjust.
 Identities = 37/100 (37%), Positives = 49/100 (49%)
 Frame = -3

Query: 481 AARIGHTGMVKLLLENGASPNLATTAGHTPLHTAAREGHVDTALALLEKEASQACMTKKG 540
           AA  G   +V+ LLENGA+ +     G  PLH A   GH +    LL   A         
Sbjct: 377 AAGFGRKDVVEHLLENGANVHARDDGGLIPLHNACSFGHAEVVQLLLRHGADPNARDNWN 198

Query: 541 FTPLHVAAKYGKVRLAELLLEHDAHPNAAGKNGLTPLHVA 580
           +TPLH AA  GK+ +  +LL+  A PN    +G T L +A
Sbjct: 197 YTPLHEAAIKGKIDVCIVLLQQCADPNIRNTDGKTALDLA 78

 Score = 56.2 bits (134), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 32/80 (40%), Positives = 47/80 (58%)
 Frame = -3

Query: 711 VASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGASPNEVSSN 770
           +A+ +G   +V+ LL++ A+V+A+   G  PLH A   GH ++V LLL++GA PN   + 
Sbjct: 380 LAAGFGRKDVVEHLLENGANVHARDDGGLIPLHNACSFGHAEVVQLLLRHGADPNARDNW 201

Query: 771 GTTPLAIAKRLGYISVTDVL 790
             TPL  A   G I V  VL
Sbjct: 200 NYTPLHEAAIKGKIDVCIVL 141

 Score = 55.8 bits (133), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 34/92 (36%), Positives = 48/92 (52%)
 Frame = -3

Query: 587 DIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQIEVARSLLQYGGSANAESVQGVTPLHLA 646
           D+V+ LL  G + H+    G  PLH A      EV + LL++G   NA      TPLH A
Sbjct: 356 DVVEHLLENGANVHARDDGGLIPLHNACSFGHAEVVQLLLRHGADPNARDNWNYTPLHEA 177

Query: 647 AQEGHTEMVALLLSKQANGNLGNKSGLTPLHL 678
           A +G  ++  +LL + A+ N+ N  G T L L
Sbjct: 176 AIKGKIDVCIVLLQQCADPNIRNTDGKTALDL 81

 Score = 55.1 bits (131), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 39/100 (39%), Positives = 55/100 (55%)
 Frame = -3

Query: 283 AARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYNAEIDDITLDH 342
           AA  G   + E LL++GA + A+   GL P+H A    H + V+LLL++ A+ +     +
Sbjct: 377 AAGFGRKDVVEHLLENGANVHARDDGGLIPLHNACSFGHAEVVQLLLRHGADPNARDNWN 198

Query: 343 LTPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIA 382
            TPLH AA  G   V  VLL + A PN R  +G T L +A
Sbjct: 197 YTPLHEAAIKGKIDVCIVLLQQCADPNIRNTDGKTALDLA 78

 Score = 55.1 bits (131), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 30/67 (44%), Positives = 40/67 (59%)
 Frame = -3

Query: 390 VMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAA 449
           V+E LL+ GA++ A  + GL PLH A   GH  +V+ LL+ GA PN  +    TPLH AA
Sbjct: 353 VVEHLLENGANVHARDDGGLIPLHNACSFGHAEVVQLLLRHGADPNARDNWNYTPLHEAA 174

Query: 450 RAGHTEV 456
             G  +V
Sbjct: 173 IKGKIDV 153

 Score = 55.1 bits (131), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 31/79 (39%), Positives = 41/79 (51%)
 Frame = -3

Query: 477 PLHCAARIGHTGMVKLLLENGASPNLATTAGHTPLHTAAREGHVDTALALLEKEASQACM 536
           PLH A   GH  +V+LLL +GA PN      +TPLH AA +G +D  + LL++ A     
Sbjct: 290 PLHNACSFGHAEVVQLLLRHGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQQCADPNIR 111

Query: 537 TKKGFTPLHVAAKYGKVRL 555
              G T L +A    K  L
Sbjct: 110 NTDGKTALDLADASAKAVL 54

 Score = 53.5 bits (127), Expect = 7e-07,   Method: Compositional matrix adjust.
 Identities = 35/100 (35%), Positives = 46/100 (46%)
 Frame = -3

Query: 514 AAREGHVDTALALLEKEASQACMTKKGFTPLHVAAKYGKVRLAELLLEHDAHPNAAGKNG 573
           AA  G  D    LLE  A+       G  PLH A  +G   + +LLL H A PNA     
Sbjct: 377 AAGFGRKDVVEHLLENGANVHARDDGGLIPLHNACSFGHAEVVQLLLRHGADPNARDNWN 198

Query: 574 LTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIA 613
            TPLH A     +D+  +LL +   P+    +G T L +A
Sbjct: 197 YTPLHEAAIKGKIDVCIVLLQQCADPNIRNTDGKTALDLA 78

 Score = 52.8 bits (125), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 41/130 (31%), Positives = 60/130 (46%)
 Frame = -3

Query: 88  IAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQNVATED 147
           +AA  G+ +VV  L+  GANV+A+   G  PL+ A    H EVV+ LL +GA+ N     
Sbjct: 380 LAAGFGRKDVVEHLLENGANVHARDDGGLIPLHNACSFGHAEVVQLLLRHGADPNARDNW 201

Query: 148 GFTPLAVALQQGHENVVAHLINYGTKGKVRLPALHIAARNDDTRTAAVLLQNDPNPDVLS 207
            +TPL       HE  +        KGK+ +                VLLQ   +P++ +
Sbjct: 200 NYTPL-------HEAAI--------KGKIDV--------------CIVLLQQCADPNIRN 108

Query: 208 KTGFTPLHIA 217
             G T L +A
Sbjct: 107 TDGKTALDLA 78

 Score = 51.2 bits (121), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 33/101 (32%), Positives = 51/101 (50%)
 Frame = -3

Query: 216 IAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETRTKD 275
           +AA +   +V + LL  GA+V+     G+ PLH A   G+  +V+LLL  GA    R   
Sbjct: 380 LAAGFGRKDVVEHLLENGANVHARDDGGLIPLHNACSFGHAEVVQLLLRHGADPNARDNW 201

Query: 276 ELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMA 316
             TPLH AA  G + +  +LL   A    +  +G + + +A
Sbjct: 200 NYTPLHEAAIKGKIDVCIVLLQQCADPNIRNTDGKTALDLA 78

 Score = 50.8 bits (120), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 34/101 (33%), Positives = 50/101 (49%)
 Frame = -3

Query: 249 IASRRGNVIMVRLLLDRGAQIETRTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKN 308
           +A+  G   +V  LL+ GA +  R    L PLH A   GH  + ++LL HGA   A+   
Sbjct: 380 LAAGFGRKDVVEHLLENGANVHARDDGGLIPLHNACSFGHAEVVQLLLRHGADPNARDNW 201

Query: 309 GLSPIHMAAQGDHLDCVRLLLQYNAEIDDITLDHLTPLHVA 349
             +P+H AA    +D   +LLQ  A+ +    D  T L +A
Sbjct: 200 NYTPLHEAAIKGKIDVCIVLLQQCADPNIRNTDGKTALDLA 78

 Score = 50.4 bits (119), Expect = 7e-06,   Method: Compositional matrix adjust.
 Identities = 34/101 (33%), Positives = 51/101 (50%)
 Frame = -3

Query: 55  LASKEGHVKMVVELLHKEIILETTTKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQK 114
           LA+  G   +V  LL     +      G   LH A   G  EVV+ L+ +GA+ NA+   
Sbjct: 380 LAAGFGRKDVVEHLLENGANVHARDDGGLIPLHNACSFGHAEVVQLLLRHGADPNARDNW 201

Query: 115 GFTPLYMAAQENHLEVVKFLLENGANQNVATEDGFTPLAVA 155
            +TPL+ AA +  ++V   LL+  A+ N+   DG T L +A
Sbjct: 200 NYTPLHEAAIKGKIDVCIVLLQQCADPNIRNTDGKTALDLA 78

 Score = 50.4 bits (119), Expect = 7e-06,   Method: Compositional matrix adjust.
 Identities = 33/102 (32%), Positives = 50/102 (49%)
 Frame = -3

Query: 612 IAAKQNQIEVARSLLQYGGSANAESVQGVTPLHLAAQEGHTEMVALLLSKQANGNLGNKS 671
           +AA   + +V   LL+ G + +A    G+ PLH A   GH E+V LLL   A+ N  +  
Sbjct: 380 LAAGFGRKDVVEHLLENGANVHARDDGGLIPLHNACSFGHAEVVQLLLRHGADPNARDNW 201

Query: 672 GLTPLHLVSQEGHVPVADVLIKHGVTVDATTRMGYTPLHVAS 713
             TPLH  + +G + V  VL++     +     G T L +A 
Sbjct: 200 NYTPLHEAAIKGKIDVCIVLLQQCADPNIRNTDGKTALDLAD 75

 Score = 48.5 bits (114), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 37/102 (36%), Positives = 48/102 (47%)
 Frame = -3

Query: 315 MAAQGDHLDCVRLLLQYNAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRALN 374
           +AA     D V  LL+  A +       L PLH A   GH  V ++LL  GA PN+R   
Sbjct: 380 LAAGFGRKDVVEHLLENGANVHARDDGGLIPLHNACSFGHAEVVQLLLRHGADPNARDNW 201

Query: 375 GFTPLHIACKKNHIRVMELLLKTGASIDAVTESGLTPLHVAS 416
            +TPLH A  K  I V  +LL+  A  +     G T L +A 
Sbjct: 200 NYTPLHEAAIKGKIDVCIVLLQQCADPNIRNTDGKTALDLAD 75

 Score = 46.2 bits (108), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 31/88 (35%), Positives = 40/88 (45%)
 Frame = -3

Query: 196 LLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGN 255
           LL+N  N       G  PLH A  + +  V QLLL  GA  N       TPLH A+ +G 
Sbjct: 341 LLENGANVHARDDGGLIPLHNACSFGHAEVVQLLLRHGADPNARDNWNYTPLHEAAIKGK 162

Query: 256 VIMVRLLLDRGAQIETRTKDELTPLHCA 283
           + +  +LL + A    R  D  T L  A
Sbjct: 161 IDVCIVLLQQCADPNIRNTDGKTALDLA 78

 Score = 45.1 bits (105), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 35/105 (33%), Positives = 46/105 (43%)
 Frame = -3

Query: 410 TPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVXXXXXXXXXXXXX 469
           TP   A F G   +V++LL+ GA+ +  +     PLH A   GH EV             
Sbjct: 389 TPSLAAGF-GRKDVVEHLLENGANVHARDDGGLIPLHNACSFGHAEVVQLLLRHGADPNA 213

Query: 470 XXXXXXTPLHCAARIGHTGMVKLLLENGASPNLATTAGHTPLHTA 514
                 TPLH AA  G   +  +LL+  A PN+  T G T L  A
Sbjct: 212 RDNWNYTPLHEAAIKGKIDVCIVLLQQCADPNIRNTDGKTALDLA 78
>00540
          Length = 3034

 Score = 71.6 bits (174), Expect = 3e-12,   Method: Compositional matrix adjust.
 Identities = 45/130 (34%), Positives = 71/130 (54%)
 Frame = -2

Query: 299  GAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYNAEIDDITLDHLTPLHVAAHCGHHRVA 358
            GA +   T++  +P+  A    HL+ V+ L+++ AEI+       T L +A + GH  V 
Sbjct: 3000 GAEVNQTTRSNSTPLRAACYDGHLEVVQFLVEHKAEIEIANSHGHTCLMIACYRGHLDVV 2821

Query: 359  KVLLDKGAKPNSRALNGFTPLHIACKKNHIRVMELLLKTGASIDAVTESGLTPLHVASFM 418
            + LL  GA+ N R++ G T LH + +   + +M+LLL  GA + A    G TPL  A+  
Sbjct: 2820 EYLLYLGAQVNRRSVKGNTALHDSAESGKLSIMKLLLSKGAKM-AKDAYGQTPLSAAAMT 2644

Query: 419  GHLPIVKNLL 428
            GH  IV+ L+
Sbjct: 2643 GHEEIVRYLI 2614

 Score = 69.7 bits (169), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 43/130 (33%), Positives = 64/130 (49%)
 Frame = -2

Query: 629  GGSANAESVQGVTPLHLAAQEGHTEMVALLLSKQANGNLGNKSGLTPLHLVSQEGHVPVA 688
            G   N  +    TPL  A  +GH E+V  L+  +A   + N  G T L +    GH+ V 
Sbjct: 3000 GAEVNQTTRSNSTPLRAACYDGHLEVVQFLVEHKAEIEIANSHGHTCLMIACYRGHLDVV 2821

Query: 689  DVLIKHGVTVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQ 748
            + L+  G  V+  +  G T LH ++  G + ++K LL   A + AK   G +PL  AA  
Sbjct: 2820 EYLLYLGAQVNRRSVKGNTALHDSAESGKLSIMKLLLSKGAKM-AKDAYGQTPLSAAAMT 2644

Query: 749  GHTDIVTLLL 758
            GH +IV  L+
Sbjct: 2643 GHEEIVRYLI 2614

 Score = 69.3 bits (168), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 45/124 (36%), Positives = 67/124 (54%)
 Frame = -2

Query: 333  AEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHIRVME 392
            AE++  T  + TPL  A + GH  V + L++  A+      +G T L IAC + H+ V+E
Sbjct: 2997 AEVNQTTRSNSTPLRAACYDGHLEVVQFLVEHKAEIEIANSHGHTCLMIACYRGHLDVVE 2818

Query: 393  LLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAG 452
             LL  GA ++  +  G T LH ++  G L I+K LL +GA     +   +TPL  AA  G
Sbjct: 2817 YLLYLGAQVNRRSVKGNTALHDSAESGKLSIMKLLLSKGAK-MAKDAYGQTPLSAAAMTG 2641

Query: 453  HTEV 456
            H E+
Sbjct: 2640 HEEI 2629

 Score = 68.6 bits (166), Expect = 3e-11,   Method: Compositional matrix adjust.
 Identities = 41/131 (31%), Positives = 68/131 (51%)
 Frame = -2

Query: 660  SKQANGNLGNKSGLTPLHLVSQEGHVPVADVLIKHGVTVDATTRMGYTPLHVASHYGNIK 719
            +K A  N   +S  TPL     +GH+ V   L++H   ++     G+T L +A + G++ 
Sbjct: 3006 AKGAEVNQTTRSNSTPLRAACYDGHLEVVQFLVEHKAEIEIANSHGHTCLMIACYRGHLD 2827

Query: 720  LVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGASPNEVSSNGTTPLAIAK 779
            +V++LL   A VN ++  G + LH +A+ G   I+ LLL  GA   +  + G TPL+ A 
Sbjct: 2826 VVEYLLYLGAQVNRRSVKGNTALHDSAESGKLSIMKLLLSKGAKMAK-DAYGQTPLSAAA 2650

Query: 780  RLGYISVTDVL 790
              G+  +   L
Sbjct: 2649 MTGHEEIVRYL 2617

 Score = 68.6 bits (166), Expect = 3e-11,   Method: Compositional matrix adjust.
 Identities = 42/131 (32%), Positives = 68/131 (51%)
 Frame = -2

Query: 265  RGAQIETRTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDC 324
            +GA++   T+   TPL  A  +GH+ + + L++H A I+    +G + + +A    HLD 
Sbjct: 3003 KGAEVNQTTRSNSTPLRAACYDGHLEVVQFLVEHKAEIEIANSHGHTCLMIACYRGHLDV 2824

Query: 325  VRLLLQYNAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACK 384
            V  LL   A+++  ++   T LH +A  G   + K+LL KGAK    A  G TPL  A  
Sbjct: 2823 VEYLLYLGAQVNRRSVKGNTALHDSAESGKLSIMKLLLSKGAKMAKDAY-GQTPLSAAAM 2647

Query: 385  KNHIRVMELLL 395
              H  ++  L+
Sbjct: 2646 TGHEEIVRYLI 2614

 Score = 65.9 bits (159), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 50/159 (31%), Positives = 74/159 (46%)
 Frame = -2

Query: 105  GANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQNVATEDGFTPLAVALQQGHENVV 164
            GA VN  ++   TPL  A  + HLEVV+FL+E+ A   +A   G T L +A  +GH +VV
Sbjct: 3000 GAEVNQTTRSNSTPLRAACYDGHLEVVQFLVEHKAEIEIANSHGHTCLMIACYRGHLDVV 2821

Query: 165  AHLINYGTKGKVRLPALHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLN 224
             +L+  G +   R                             S  G T LH +A    L+
Sbjct: 2820 EYLLYLGAQVNRR-----------------------------SVKGNTALHDSAESGKLS 2728

Query: 225  VAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLLL 263
            + +LLL++GA +      G TPL  A+  G+  +VR L+
Sbjct: 2727 IMKLLLSKGAKMA-KDAYGQTPLSAAAMTGHEEIVRYLI 2614

 Score = 65.9 bits (159), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 43/131 (32%), Positives = 62/131 (47%)
 Frame = -2

Query: 364  KGAKPNSRALNGFTPLHIACKKNHIRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPI 423
            KGA+ N    +  TPL  AC   H+ V++ L++  A I+     G T L +A + GHL +
Sbjct: 3003 KGAEVNQTTRSNSTPLRAACYDGHLEVVQFLVEHKAEIEIANSHGHTCLMIACYRGHLDV 2824

Query: 424  VKNLLQRGASPNVSNVKVETPLHMAARAGHTEVXXXXXXXXXXXXXXXXXXXTPLHCAAR 483
            V+ LL  GA  N  +VK  T LH +A +G   +                   TPL  AA 
Sbjct: 2823 VEYLLYLGAQVNRRSVKGNTALHDSAESGKLSI-MKLLLSKGAKMAKDAYGQTPLSAAAM 2647

Query: 484  IGHTGMVKLLL 494
             GH  +V+ L+
Sbjct: 2646 TGHEEIVRYLI 2614

 Score = 64.3 bits (155), Expect = 4e-10,   Method: Compositional matrix adjust.
 Identities = 50/151 (33%), Positives = 66/151 (43%), Gaps = 5/151 (3%)
 Frame = -2

Query: 496  NGASPNLATTAGHTPLHTAAREGHVDTALALLEKEASQACMTKKGFTPLHVAAKYGKVRL 555
             GA  N  T +  TPL  A  +GH++    L+E +A        G T L +A   G + +
Sbjct: 3003 KGAEVNQTTRSNSTPLRAACYDGHLEVVQFLVEHKAEIEIANSHGHTCLMIACYRGHLDV 2824

Query: 556  AELLLEHDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAK 615
             E LL   A  N     G T LH +     L I+KLLL +G      A+ G TPL  AA 
Sbjct: 2823 VEYLLYLGAQVNRRSVKGNTALHDSAESGKLSIMKLLLSKGAKMAKDAY-GQTPLSAAAM 2647

Query: 616  QNQIEVARSLLQY-----GGSANAESVQGVT 641
                E+ R L+       G  ANA  + G T
Sbjct: 2646 TGHEEIVRYLISGPLFTPGEQANALELMGAT 2554

 Score = 62.4 bits (150), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 50/163 (30%), Positives = 75/163 (46%), Gaps = 6/163 (3%)
 Frame = -2

Query: 564  AHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQIEVAR 623
            A  N   ++  TPL  A +  +L++V+ L+           +G+T L IA  +  ++V  
Sbjct: 2997 AEVNQTTRSNSTPLRAACYDGHLEVVQFLVEHKAEIEIANSHGHTCLMIACYRGHLDVVE 2818

Query: 624  SLLQYGGSANAESVQGVTPLHLAAQEGHTEMVALLLSKQANGNLGNKSGLTPLHLVSQEG 683
             LL  G   N  SV+G T LH +A+ G   ++ LLLSK A     +  G TPL   +  G
Sbjct: 2817 YLLYLGAQVNRRSVKGNTALHDSAESGKLSIMKLLLSKGAK-MAKDAYGQTPLSAAAMTG 2641

Query: 684  HVPVADVLIKH-----GVTVDATTRMGYTPLHVA-SHYGNIKL 720
            H  +   LI       G   +A   MG T +  +  H G +KL
Sbjct: 2640 HEEIVRYLISGPLFTPGEQANALELMGATLVDKSRDHAGAVKL 2512

 Score = 58.5 bits (140), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 43/118 (36%), Positives = 60/118 (50%)
 Frame = -2

Query: 476  TPLHCAARIGHTGMVKLLLENGASPNLATTAGHTPLHTAAREGHVDTALALLEKEASQAC 535
            TPL  A   GH  +V+ L+E+ A   +A + GHT L  A   GH+D    LL   A    
Sbjct: 2964 TPLRAACYDGHLEVVQFLVEHKAEIEIANSHGHTCLMIACYRGHLDVVEYLLYLGAQVNR 2785

Query: 536  MTKKGFTPLHVAAKYGKVRLAELLLEHDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLL 593
             + KG T LH +A+ GK+ + +LLL   A   A    G TPL  A    + +IV+ L+
Sbjct: 2784 RSVKGNTALHDSAESGKLSIMKLLLSKGA-KMAKDAYGQTPLSAAAMTGHEEIVRYLI 2614

 Score = 55.8 bits (133), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 43/130 (33%), Positives = 69/130 (53%), Gaps = 1/130 (0%)
 Frame = -2

Query: 7    RSGSDPAADAATSFLRAA-RSGNLDKALDHLRNGVDINTCNQNGLNGLHLASKEGHVKMV 65
            RS S P        LRAA   G+L+     + +  +I   N +G   L +A   GH+ +V
Sbjct: 2976 RSNSTP--------LRAACYDGHLEVVQFLVEHKAEIEIANSHGHTCLMIACYRGHLDVV 2821

Query: 66   VELLHKEIILETTTKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQE 125
              LL+    +   + KGNTALH +A +G+  +++ L++ GA + A+   G TPL  AA  
Sbjct: 2820 EYLLYLGAQVNRRSVKGNTALHDSAESGKLSIMKLLLSKGAKM-AKDAYGQTPLSAAAMT 2644

Query: 126  NHLEVVKFLL 135
             H E+V++L+
Sbjct: 2643 GHEEIVRYLI 2614

 Score = 50.8 bits (120), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 32/96 (33%), Positives = 50/96 (52%)
 Frame = -2

Query: 78   TTKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLEN 137
            TT+  +T L  A   G  EVV+ LV + A +   +  G T L +A    HL+VV++LL  
Sbjct: 2982 TTRSNSTPLRAACYDGHLEVVQFLVEHKAEIEIANSHGHTCLMIACYRGHLDVVEYLLYL 2803

Query: 138  GANQNVATEDGFTPLAVALQQGHENVVAHLINYGTK 173
            GA  N  +  G T L  + + G  +++  L++ G K
Sbjct: 2802 GAQVNRRSVKGNTALHDSAESGKLSIMKLLLSKGAK 2695

 Score = 37.4 bits (85), Expect = 0.054,   Method: Compositional matrix adjust.
 Identities = 27/81 (33%), Positives = 39/81 (48%), Gaps = 16/81 (19%)
 Frame = -2

Query: 374  NGFTPLHIACKKN-------------HIRVMELLLKTGASIDAVTESGLTPLHVASFMG- 419
            +G +PLH+AC +N              + V  +L+K GA  +A    G   LH AS MG 
Sbjct: 1848 DGASPLHLACMENISSFGRVRMSHFPSLSVTRILIKVGADTNARDSQGNVALHFAS-MGK 1672

Query: 420  --HLPIVKNLLQRGASPNVSN 438
               + +V+ LL  GA  +V N
Sbjct: 1671 KVRMAVVEALLAGGAHADVCN 1609
>02055
          Length = 1740

 Score = 70.5 bits (171), Expect = 6e-12,   Method: Compositional matrix adjust.
 Identities = 62/212 (29%), Positives = 102/212 (48%), Gaps = 4/212 (1%)
 Frame = +3

Query: 573 GLTPLHVAVHHNNLDIVKLLLPRGGSPHSPA-WNGYTPLHIAAK-QNQIEVARSLLQYGG 630
           G TPLH+A  H N + +  L+  G + ++ A +   TPLH+A + + Q EVA  L+Q G 
Sbjct: 423 GDTPLHIATVHANHEAMGALVRNGANVNARAKFLNSTPLHVACRLRGQQEVA-LLIQLGA 599

Query: 631 SANAESVQGVTPLHLAAQEGHTEMVALLLSKQANGNLGNKSGLTPLHLVSQEGHVPVADV 690
             +     G TPL +A +     +V +LL  Q +  +  +          Q+  + +  +
Sbjct: 600 RIDVNDATGTTPLQMACKRADPAVVNILLRSQPSI-VRTEDANKLFKYAIQKRQLHIVKM 776

Query: 691 LIKHGVTVDATTRMGYTPLHVASHYGNIKLVKFLL-QHQADVNAKTKLGYSPLHQAAQQG 749
           L + GV V+     G TP+H+A       + KF +  ++ + + +   G +PL  A   G
Sbjct: 777 LCEAGVAVNYE---GTTPVHIAMDNQAWDIAKFFITSNKHNFDGRDSKGRTPLCLALLSG 947

Query: 750 -HTDIVTLLLKNGASPNEVSSNGTTPLAIAKR 780
               +V+ LL  G S ++V SNG T L  A R
Sbjct: 948 ADFHMVSFLLNVGYSIDQVDSNGETWLLRAGR 1043

 Score = 65.9 bits (159), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 73/280 (26%), Positives = 122/280 (43%), Gaps = 7/280 (2%)
 Frame = +3

Query: 389 RVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPNV-SNVKVETPLHM 447
           R ++ L++ GA +D     G TPLH+A+   +   +  L++ GA+ N  +     TPLH+
Sbjct: 366 REVDDLIRCGADVDFCNMFGDTPLHIATVHANHEAMGALVRNGANVNARAKFLNSTPLHV 545

Query: 448 AARAGHTEVXXXXXXXXXXXXXXXXXXXTPLHCAARIGHTGMVKLLLENGASPNLATTAG 507
           A R    +                    TPL  A +     +V +LL   + P++  T  
Sbjct: 546 ACRLRGQQEVALLIQLGARIDVNDATGTTPLQMACKRADPAVVNILLR--SQPSIVRTED 719

Query: 508 HTPLHTAA---REGHVDTALALLEKEASQACMTKKGFTPLHVAAKYGKVRLAELLLEHDA 564
              L   A   R+ H+   L     EA  A +  +G TP+H+A       +A+  +  + 
Sbjct: 720 ANKLFKYAIQKRQLHIVKMLC----EAGVA-VNYEGTTPVHIAMDNQAWDIAKFFITSNK 884

Query: 565 HPNAAGKN--GLTPLHVAVHHN-NLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQIEV 621
           H N  G++  G TPL +A+    +  +V  LL  G S      NG T L  A +QN+  +
Sbjct: 885 H-NFDGRDSKGRTPLCLALLSGADFHMVSFLLNVGYSIDQVDSNGETWLLRAGRQNEENL 1061

Query: 622 ARSLLQYGGSANAESVQGVTPLHLAAQEGHTEMVALLLSK 661
             S+L++  +  A +   V  +     +GH  +V  L+ K
Sbjct: 1062VCSILRFNPNVYAPNRYNVPLVLELFDKGHYAIVNHLVRK 1181

 Score = 63.5 bits (153), Expect = 7e-10,   Method: Compositional matrix adjust.
 Identities = 66/285 (23%), Positives = 113/285 (39%), Gaps = 3/285 (1%)
 Frame = +3

Query: 424 VKNLLQRGASPNVSNVKVETPLHMA-ARAGHTEVXXXXXXXXXXXXXXXXXXXTPLHCAA 482
           V +L++ GA  +  N+  +TPLH+A   A H  +                   TPLH A 
Sbjct: 372 VDDLIRCGADVDFCNMFGDTPLHIATVHANHEAMGALVRNGANVNARAKFLNSTPLHVAC 551

Query: 483 RIGHTGMVKLLLENGASPNLATTAGHTPLHTAAREGHVDTALALLEKEASQACMTKKGFT 542
           R+     V LL++ GA  ++    G TPL  A +         LL  + S    T+    
Sbjct: 552 RLRGQQEVALLIQLGARIDVNDATGTTPLQMACKRADPAVVNILLRSQPS-IVRTEDANK 728

Query: 543 PLHVAAKYGKVRLAELLLEHDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGG-SPHS 601
               A +  ++ + ++L E      A    G TP+H+A+ +   DI K  +     +   
Sbjct: 729 LFKYAIQKRQLHIVKMLCEAGV---AVNYEGTTPVHIAMDNQAWDIAKFFITSNKHNFDG 899

Query: 602 PAWNGYTPLHIAAKQN-QIEVARSLLQYGGSANAESVQGVTPLHLAAQEGHTEMVALLLS 660
               G TPL +A        +   LL  G S +     G T L  A ++    +V  +L 
Sbjct: 900 RDSKGRTPLCLALLSGADFHMVSFLLNVGYSIDQVDSNGETWLLRAGRQNEENLVCSILR 1079

Query: 661 KQANGNLGNKSGLTPLHLVSQEGHVPVADVLIKHGVTVDATTRMG 705
              N    N+  +  +  +  +GH  + + L++  ++     R+G
Sbjct: 1080FNPNVYAPNRYNVPLVLELFDKGHYAIVNHLVRKIISTVRNKRIG 1214

 Score = 62.4 bits (150), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 68/226 (30%), Positives = 98/226 (43%), Gaps = 5/226 (2%)
 Frame = +3

Query: 34  DHLRNGVDINTCNQNGLNGLHLASKEGHVKMVVELLHKEIILETTTKKGN-TALHIAA-L 91
           D +R G D++ CN  G   LH+A+   + + +  L+     +    K  N T LH+A  L
Sbjct: 378 DLIRCGADVDFCNMFGDTPLHIATVHANHEAMGALVRNGANVNARAKFLNSTPLHVACRL 557

Query: 92  AGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQNVATEDGFTP 151
            GQ EV   L+  GA ++     G TPL MA +     VV  LL +  +  V TED    
Sbjct: 558 RGQQEVAL-LIQLGARIDVNDATGTTPLQMACKRADPAVVNILLRSQPSI-VRTEDANKL 731

Query: 152 LAVALQQGHENVVAHLINYGTKGKVR-LPALHIAARNDDTRTAAVLL-QNDPNPDVLSKT 209
              A+Q+   ++V  L   G          +HIA  N     A   +  N  N D     
Sbjct: 732 FKYAIQKRQLHIVKMLCEAGVAVNYEGTTPVHIAMDNQAWDIAKFFITSNKHNFDGRDSK 911

Query: 210 GFTPLHIA-AHYENLNVAQLLLNRGASVNFTPQNGITPLHIASRRG 254
           G TPL +A     + ++   LLN G S++    NG T L  A R+ 
Sbjct: 912 GRTPLCLALLSGADFHMVSFLLNVGYSIDQVDSNGETWLLRAGRQN 1049

 Score = 60.8 bits (146), Expect = 5e-09,   Method: Compositional matrix adjust.
 Identities = 66/225 (29%), Positives = 93/225 (41%), Gaps = 3/225 (1%)
 Frame = +3

Query: 229 LLNRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETRTKD-ELTPLHCAARNG 287
           L+  GA V+F    G TPLHIA+   N   +  L+  GA +  R K    TPLH A R  
Sbjct: 381 LIRCGADVDFCNMFGDTPLHIATVHANHEAMGALVRNGANVNARAKFLNSTPLHVACRLR 560

Query: 288 HVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYNAEIDDITLDHLTPLH 347
             +   +L+  GA I      G +P+ MA +      V +LL+    I   T D      
Sbjct: 561 GQQEVALLIQLGARIDVNDATGTTPLQMACKRADPAVVNILLRSQPSIVR-TEDANKLFK 737

Query: 348 VAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHIRVMELLLKTGA-SIDAVTE 406
            A       + K+L + G   N     G TP+HIA       + +  + +   + D    
Sbjct: 738 YAIQKRQLHIVKMLCEAGVAVNYE---GTTPVHIAMDNQAWDIAKFFITSNKHNFDGRDS 908

Query: 407 SGLTPLHVASFMG-HLPIVKNLLQRGASPNVSNVKVETPLHMAAR 450
            G TPL +A   G    +V  LL  G S +  +   ET L  A R
Sbjct: 909 KGRTPLCLALLSGADFHMVSFLLNVGYSIDQVDSNGETWLLRAGR 1043

 Score = 60.5 bits (145), Expect = 7e-09,   Method: Compositional matrix adjust.
 Identities = 67/255 (26%), Positives = 113/255 (44%), Gaps = 5/255 (1%)
 Frame = +3

Query: 181 LHIAARNDDTRTAAVLLQNDPNPDVLSK-TGFTPLHIAAHYENLNVAQLLLNRGASVNFT 239
           LHIA  + +      L++N  N +  +K    TPLH+A          LL+  GA ++  
Sbjct: 435 LHIATVHANHEAMGALVRNGANVNARAKFLNSTPLHVACRLRGQQEVALLIQLGARIDVN 614

Query: 240 PQNGITPLHIASRRGNVIMVRLLLDRGAQIETRTKDELTPLHCAARNGHVRISEILLDHG 299
              G TPL +A +R +  +V +LL     I  RT+D       A +   + I ++L + G
Sbjct: 615 DATGTTPLQMACKRADPAVVNILLRSQPSI-VRTEDANKLFKYAIQKRQLHIVKMLCEAG 791

Query: 300 APIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYNA-EIDDITLDHLTPLHVAAHCG--HHR 356
             +  +   G +P+H+A      D  +  +  N    D       TPL +A   G   H 
Sbjct: 792 VAVNYE---GTTPVHIAMDNQAWDIAKFFITSNKHNFDGRDSKGRTPLCLALLSGADFHM 962

Query: 357 VAKVLLDKGAKPNSRALNGFTPLHIACKKNHIRVMELLLKTGASIDAVTESGLTPLHVAS 416
           V+  LL+ G   +    NG T L  A ++N   ++  +L+   ++ A     + PL +  
Sbjct: 963 VS-FLLNVGYSIDQVDSNGETWLLRAGRQNEENLVCSILRFNPNVYAPNRYNV-PLVLEL 1136

Query: 417 F-MGHLPIVKNLLQR 430
           F  GH  IV +L+++
Sbjct: 1137FDKGHYAIVNHLVRK 1181

 Score = 58.9 bits (141), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 40/121 (33%), Positives = 68/121 (56%), Gaps = 1/121 (0%)
 Frame = +3

Query: 689 DVLIKHGVTVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTK-LGYSPLHQAAQ 747
           D LI+ G  VD     G TPLH+A+ + N + +  L+++ A+VNA+ K L  +PLH A +
Sbjct: 375 DDLIRCGADVDFCNMFGDTPLHIATVHANHEAMGALVRNGANVNARAKFLNSTPLHVACR 554

Query: 748 QGHTDIVTLLLKNGASPNEVSSNGTTPLAIAKRLGYISVTDVLKVVTDETSVVLVSDKHR 807
                 V LL++ GA  +   + GTTPL +A +    +V ++L  +  + S+V   D ++
Sbjct: 555 LRGQQEVALLIQLGARIDVNDATGTTPLQMACKRADPAVVNIL--LRSQPSIVRTEDANK 728

Query: 808 M 808
           +
Sbjct: 729 L 731

 Score = 50.4 bits (119), Expect = 7e-06,   Method: Compositional matrix adjust.
 Identities = 61/237 (25%), Positives = 98/237 (41%), Gaps = 4/237 (1%)
 Frame = +3

Query: 295 LLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYNAEID-DITLDHLTPLHVAAHCG 353
           L+  GA +      G +P+H+A    + + +  L++  A ++      + TPLHVA    
Sbjct: 381 LIRCGADVDFCNMFGDTPLHIATVHANHEAMGALVRNGANVNARAKFLNSTPLHVACRLR 560

Query: 354 HHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHIRVMELLLKTGASIDAVTESGLTPLH 413
             +   +L+  GA+ +     G TPL +ACK+    V+ +LL++  SI   TE       
Sbjct: 561 GQQEVALLIQLGARIDVNDATGTTPLQMACKRADPAVVNILLRSQPSI-VRTEDANKLFK 737

Query: 414 VASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVXXXXXXXXXXXXX-XXX 472
            A     L IVK L + G + N       TP+H+A      ++                 
Sbjct: 738 YAIQKRQLHIVKMLCEAGVAVNYEGT---TPVHIAMDNQAWDIAKFFITSNKHNFDGRDS 908

Query: 473 XXXTPLHCAARIGHTG--MVKLLLENGASPNLATTAGHTPLHTAAREGHVDTALALL 527
              TPL C A +      MV  LL  G S +   + G T L  A R+   +   ++L
Sbjct: 909 KGRTPL-CLALLSGADFHMVSFLLNVGYSIDQVDSNGETWLLRAGRQNEENLVCSIL 1076
>21532
          Length = 460

 Score = 65.9 bits (159), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 41/116 (35%), Positives = 59/116 (50%), Gaps = 7/116 (6%)
 Frame = -1

Query: 222 NLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQ-------IETRTK 274
           N+ +   LL+ GA VN     G TP   A   GN+  V+ LL  G         I  R  
Sbjct: 460 NVPIINTLLSHGADVNIRDNTGCTPFANACCLGNLAAVKALLTPGESPSWSKPMINVRDN 281

Query: 275 DELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQ 330
            + TPLH A++ GH  I E+L++H A + AK  +G +P+ +A Q  H + V +L Q
Sbjct: 280 SQNTPLHLASQEGHTAIVELLVEHKADLAAKNDSGHNPLSLARQYKHENVVAVLQQ 113

 Score = 60.1 bits (144), Expect = 8e-09,   Method: Compositional matrix adjust.
 Identities = 38/124 (30%), Positives = 64/124 (51%), Gaps = 7/124 (5%)
 Frame = -1

Query: 684 HVPVADVLIKHGVTVDATTRMGYTPLHVASHYGNIKLVKFLLQ-------HQADVNAKTK 736
           +VP+ + L+ HG  V+     G TP   A   GN+  VK LL         +  +N +  
Sbjct: 460 NVPIINTLLSHGADVNIRDNTGCTPFANACCLGNLAAVKALLTPGESPSWSKPMINVRDN 281

Query: 737 LGYSPLHQAAQQGHTDIVTLLLKNGASPNEVSSNGTTPLAIAKRLGYISVTDVLKVVTDE 796
              +PLH A+Q+GHT IV LL+++ A     + +G  PL++A++  + +V  VL+   + 
Sbjct: 280 SQNTPLHLASQEGHTAIVELLVEHKADLAAKNDSGHNPLSLARQYKHENVVAVLQQAENT 101

Query: 797 TSVV 800
             V+
Sbjct: 100 EPVI 89

 Score = 55.1 bits (131), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 35/116 (30%), Positives = 54/116 (46%), Gaps = 7/116 (6%)
 Frame = -1

Query: 618 QIEVARSLLQYGGSANAESVQGVTPLHLAAQEGHTEMVALLLS-------KQANGNLGNK 670
            + +  +LL +G   N     G TP   A   G+   V  LL+        +   N+ + 
Sbjct: 460 NVPIINTLLSHGADVNIRDNTGCTPFANACCLGNLAAVKALLTPGESPSWSKPMINVRDN 281

Query: 671 SGLTPLHLVSQEGHVPVADVLIKHGVTVDATTRMGYTPLHVASHYGNIKLVKFLLQ 726
           S  TPLHL SQEGH  + ++L++H   + A    G+ PL +A  Y +  +V  L Q
Sbjct: 280 SQNTPLHLASQEGHTAIVELLVEHKADLAAKNDSGHNPLSLARQYKHENVVAVLQQ 113

 Score = 54.7 bits (130), Expect = 4e-07,   Method: Compositional matrix adjust.
 Identities = 33/111 (29%), Positives = 58/111 (52%), Gaps = 7/111 (6%)
 Frame = -1

Query: 654 MVALLLSKQANGNLGNKSGLTPLHLVSQEGHVPVADVLIKHGVT-------VDATTRMGY 706
           ++  LLS  A+ N+ + +G TP       G++     L+  G +       ++       
Sbjct: 451 IINTLLSHGADVNIRDNTGCTPFANACCLGNLAAVKALLTPGESPSWSKPMINVRDNSQN 272

Query: 707 TPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLL 757
           TPLH+AS  G+  +V+ L++H+AD+ AK   G++PL  A Q  H ++V +L
Sbjct: 271 TPLHLASQEGHTAIVELLVEHKADLAAKNDSGHNPLSLARQYKHENVVAVL 119

 Score = 51.2 bits (121), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 39/147 (26%), Positives = 62/147 (42%)
 Frame = -1

Query: 387 HIRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLH 446
           ++ ++  LL  GA ++    +G TP   A  +G+L  VK LL  G SP+ S   +     
Sbjct: 460 NVPIINTLLSHGADVNIRDNTGCTPFANACCLGNLAAVKALLTPGESPSWSKPMINV--- 290

Query: 447 MAARAGHTEVXXXXXXXXXXXXXXXXXXXTPLHCAARIGHTGMVKLLLENGASPNLATTA 506
                                        TPLH A++ GHT +V+LL+E+ A       +
Sbjct: 289 -----------------------RDNSQNTPLHLASQEGHTAIVELLVEHKADLAAKNDS 179

Query: 507 GHTPLHTAAREGHVDTALALLEKEASQ 533
           GH PL  A +  H +    L + E ++
Sbjct: 178 GHNPLSLARQYKHENVVAVLQQAENTE 98

 Score = 48.5 bits (114), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 24/60 (40%), Positives = 37/60 (61%)
 Frame = -1

Query: 108 VNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQNVATEDGFTPLAVALQQGHENVVAHL 167
           +N +     TPL++A+QE H  +V+ L+E+ A+     + G  PL++A Q  HENVVA L
Sbjct: 298 INVRDNSQNTPLHLASQEGHTAIVELLVEHKADLAAKNDSGHNPLSLARQYKHENVVAVL 119

 Score = 47.0 bits (110), Expect = 8e-05,   Method: Compositional matrix adjust.
 Identities = 37/117 (31%), Positives = 52/117 (44%), Gaps = 10/117 (8%)
 Frame = -1

Query: 552 KVRLAELLLEHDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNG----- 606
            V +   LL H A  N     G TP   A    NL  VK LL  G    SP+W+      
Sbjct: 460 NVPIINTLLSHGADVNIRDNTGCTPFANACCLGNLAAVKALLTPG---ESPSWSKPMINV 290

Query: 607 -----YTPLHIAAKQNQIEVARSLLQYGGSANAESVQGVTPLHLAAQEGHTEMVALL 658
                 TPLH+A+++    +   L+++     A++  G  PL LA Q  H  +VA+L
Sbjct: 289 RDNSQNTPLHLASQEGHTAIVELLVEHKADLAAKNDSGHNPLSLARQYKHENVVAVL 119

 Score = 43.9 bits (102), Expect = 6e-04,   Method: Compositional matrix adjust.
 Identities = 33/111 (29%), Positives = 52/111 (46%), Gaps = 7/111 (6%)
 Frame = -1

Query: 489 MVKLLLENGASPNLATTAGHTPLHTAAREGHVDTALALLEKEASQA-------CMTKKGF 541
           ++  LL +GA  N+    G TP   A   G++    ALL    S +              
Sbjct: 451 IINTLLSHGADVNIRDNTGCTPFANACCLGNLAAVKALLTPGESPSWSKPMINVRDNSQN 272

Query: 542 TPLHVAAKYGKVRLAELLLEHDAHPNAAGKNGLTPLHVAVHHNNLDIVKLL 592
           TPLH+A++ G   + ELL+EH A   A   +G  PL +A  + + ++V +L
Sbjct: 271 TPLHLASQEGHTAIVELLVEHKADLAAKNDSGHNPLSLARQYKHENVVAVL 119

 Score = 43.5 bits (101), Expect = 8e-04,   Method: Compositional matrix adjust.
 Identities = 35/107 (32%), Positives = 47/107 (43%), Gaps = 7/107 (6%)
 Frame = -1

Query: 357 VAKVLLDKGAKPNSRALNGFTPLHIACKKNHIRVMELLLKTGAS-------IDAVTESGL 409
           +   LL  GA  N R   G TP   AC   ++  ++ LL  G S       I+    S  
Sbjct: 451 IINTLLSHGADVNIRDNTGCTPFANACCLGNLAAVKALLTPGESPSWSKPMINVRDNSQN 272

Query: 410 TPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEV 456
           TPLH+AS  GH  IV+ L++  A     N     PL +A +  H  V
Sbjct: 271 TPLHLASQEGHTAIVELLVEHKADLAAKNDSGHNPLSLARQYKHENV 131

 Score = 43.5 bits (101), Expect = 9e-04,   Method: Compositional matrix adjust.
 Identities = 34/112 (30%), Positives = 52/112 (46%), Gaps = 7/112 (6%)
 Frame = -1

Query: 325 VRLLLQYNAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKP-------NSRALNGFT 377
           +  LL + A+++       TP   A   G+    K LL  G  P       N R  +  T
Sbjct: 448 INTLLSHGADVNIRDNTGCTPFANACCLGNLAAVKALLTPGESPSWSKPMINVRDNSQNT 269

Query: 378 PLHIACKKNHIRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQ 429
           PLH+A ++ H  ++ELL++  A + A  +SG  PL +A    H  +V  L Q
Sbjct: 268 PLHLASQEGHTAIVELLVEHKADLAAKNDSGHNPLSLARQYKHENVVAVLQQ 113

 Score = 30.4 bits (67), Expect = 6.8,   Method: Compositional matrix adjust.
 Identities = 31/132 (23%), Positives = 55/132 (41%), Gaps = 2/132 (1%)
 Frame = -1

Query: 130 VVKFLLENGANQNVATEDGFTPLAVALQQGHENVVAHLINYGTKGKVRLPALHIAARNDD 189
           ++  LL +GA+ N+    G TP A A   G+   V  L+  G       P +++    D+
Sbjct: 451 IINTLLSHGADVNIRDNTGCTPFANACCLGNLAAVKALLTPGESPSWSKPMINV---RDN 281

Query: 190 TRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHI 249
           ++                    TPLH+A+   +  + +LL+   A +     +G  PL +
Sbjct: 280 SQN-------------------TPLHLASQEGHTAIVELLVEHKADLAAKNDSGHNPLSL 158

Query: 250 AS--RRGNVIMV 259
           A   +  NV+ V
Sbjct: 157 ARQYKHENVVAV 122
>20792
          Length = 441

 Score = 65.5 bits (158), Expect(2) = 2e-10,   Method: Composition-based stats.
 Identities = 33/96 (34%), Positives = 52/96 (54%)
 Frame = +2

Query: 659 LSKQANGNLGNKSGLTPLHLVSQEGHVPVADVLIKHGVTVDATTRMGYTPLHVASHYGNI 718
           L  + +  +GN  G  PLH  +Q G +   + L++ GV VD   R  +TPL +A     +
Sbjct: 38  LCDEVDLQIGNFEGKKPLHETAQFGQLDCMNFLLQRGVQVDCLKRADWTPLMLACTKCQL 217

Query: 719 KLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIV 754
            ++  LL+H AD     K G++  H AA++GH DI+
Sbjct: 218 PVISLLLKHGADPALVNKDGWNSFHIAAREGHVDIL 325

 Score = 20.0 bits (40), Expect(2) = 2e-10,   Method: Compositional matrix adjust.
 Identities = 12/29 (41%), Positives = 13/29 (44%)
 Frame = +3

Query: 755 TLLLKNGASPNEVSSNGTTPLAIAKRLGY 783
           TLL  N    N  S N  TPL  A   G+
Sbjct: 330 TLLASNAGVWNVSSHNSRTPLHTAALHGH 416

 Score = 55.8 bits (133), Expect(2) = 5e-10,   Method: Composition-based stats.
 Identities = 27/84 (32%), Positives = 44/84 (52%)
 Frame = +2

Query: 507 GHTPLHTAAREGHVDTALALLEKEASQACMTKKGFTPLHVAAKYGKVRLAELLLEHDAHP 566
           G  PLH  A+ G +D    LL++     C+ +  +TPL +A    ++ +  LLL+H A P
Sbjct: 77  GKKPLHETAQFGQLDCMNFLLQRGVQVDCLKRADWTPLMLACTKCQLPVISLLLKHGADP 256

Query: 567 NAAGKNGLTPLHVAVHHNNLDIVK 590
               K+G    H+A    ++DI+K
Sbjct: 257 ALVNKDGWNSFHIAAREGHVDILK 328

 Score = 28.1 bits (61), Expect(2) = 5e-10,   Method: Compositional matrix adjust.
 Identities = 15/35 (42%), Positives = 17/35 (48%)
 Frame = +3

Query: 625 LLQYGGSANAESVQGVTPLHLAAQEGHTEMVALLL 659
           L    G  N  S    TPLH AA  GH+E V  +L
Sbjct: 336 LASNAGVWNVSSHNSRTPLHTAALHGHSEAVRFML 440

 Score = 55.8 bits (133), Expect(2) = 1e-09,   Method: Composition-based stats.
 Identities = 27/84 (32%), Positives = 41/84 (48%)
 Frame = +2

Query: 373 LNGFTPLHIACKKNHIRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGA 432
             G  PLH   +   +  M  LL+ G  +D +  +  TPL +A     LP++  LL+ GA
Sbjct: 71  FEGKKPLHETAQFGQLDCMNFLLQRGVQVDCLKRADWTPLMLACTKCQLPVISLLLKHGA 250

Query: 433 SPNVSNVKVETPLHMAARAGHTEV 456
            P + N       H+AAR GH ++
Sbjct: 251 DPALVNKDGWNSFHIAAREGHVDI 322

 Score = 26.6 bits (57), Expect(2) = 1e-09,   Method: Compositional matrix adjust.
 Identities = 14/36 (38%), Positives = 19/36 (52%)
 Frame = +3

Query: 492 LLLENGASPNLATTAGHTPLHTAAREGHVDTALALL 527
           LL  N    N+++    TPLHTAA  GH +    +L
Sbjct: 333 LLASNAGVWNVSSHNSRTPLHTAALHGHSEAVRFML 440

 Score = 55.5 bits (132), Expect(2) = 4e-09,   Method: Composition-based stats.
 Identities = 30/82 (36%), Positives = 42/82 (51%)
 Frame = +2

Query: 345 PLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHIRVMELLLKTGASIDAV 404
           PLH  A  G       LL +G + +      +TPL +AC K  + V+ LLLK GA    V
Sbjct: 86  PLHETAQFGQLDCMNFLLQRGVQVDCLKRADWTPLMLACTKCQLPVISLLLKHGADPALV 265

Query: 405 TESGLTPLHVASFMGHLPIVKN 426
            + G    H+A+  GH+ I+KN
Sbjct: 266 NKDGWNSFHIAAREGHVDILKN 331

 Score = 25.4 bits (54), Expect(2) = 4e-09,   Method: Compositional matrix adjust.
 Identities = 16/32 (50%), Positives = 18/32 (56%), Gaps = 1/32 (3%)
 Frame = +3

Query: 425 KNLLQRGAS-PNVSNVKVETPLHMAARAGHTE 455
           K LL   A   NVS+    TPLH AA  GH+E
Sbjct: 327 KTLLASNAGVWNVSSHNSRTPLHTAALHGHSE 422

 Score = 56.6 bits (135), Expect = 9e-08,   Method: Composition-based stats.
 Identities = 30/90 (33%), Positives = 48/90 (53%)
 Frame = +2

Query: 705 GYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGASP 764
           G  PLH  + +G +  + FLLQ    V+   +  ++PL  A  +    +++LLLK+GA P
Sbjct: 77  GKKPLHETAQFGQLDCMNFLLQRGVQVDCLKRADWTPLMLACTKCQLPVISLLLKHGADP 256

Query: 765 NEVSSNGTTPLAIAKRLGYISVTDVLKVVT 794
             V+ +G     IA R G++   D+LK  T
Sbjct: 257 ALVNKDGWNSFHIAAREGHV---DILKNTT 337

 Score = 50.1 bits (118), Expect(2) = 1e-07,   Method: Composition-based stats.
 Identities = 28/84 (33%), Positives = 42/84 (50%)
 Frame = +2

Query: 604 WNGYTPLHIAAKQNQIEVARSLLQYGGSANAESVQGVTPLHLAAQEGHTEMVALLLSKQA 663
           + G  PLH  A+  Q++    LLQ G   +       TPL LA  +    +++LLL   A
Sbjct: 71  FEGKKPLHETAQFGQLDCMNFLLQRGVQVDCLKRADWTPLMLACTKCQLPVISLLLKHGA 250

Query: 664 NGNLGNKSGLTPLHLVSQEGHVPV 687
           +  L NK G    H+ ++EGHV +
Sbjct: 251 DPALVNKDGWNSFHIAAREGHVDI 322

 Score = 25.4 bits (54), Expect(2) = 1e-07,   Method: Compositional matrix adjust.
 Identities = 15/38 (39%), Positives = 20/38 (52%), Gaps = 1/38 (2%)
 Frame = +3

Query: 722 KFLLQHQADV-NAKTKLGYSPLHQAAQQGHTDIVTLLL 758
           K LL   A V N  +    +PLH AA  GH++ V  +L
Sbjct: 327 KTLLASNAGVWNVSSHNSRTPLHTAALHGHSEAVRFML 440

 Score = 53.1 bits (126), Expect(2) = 2e-07,   Method: Composition-based stats.
 Identities = 30/82 (36%), Positives = 39/82 (47%)
 Frame = +2

Query: 210 GFTPLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQI 269
           G  PLH  A +  L+    LL RG  V+   +   TPL +A  +  + ++ LLL  GA  
Sbjct: 77  GKKPLHETAQFGQLDCMNFLLQRGVQVDCLKRADWTPLMLACTKCQLPVISLLLKHGADP 256

Query: 270 ETRTKDELTPLHCAARNGHVRI 291
               KD     H AAR GHV I
Sbjct: 257 ALVNKDGWNSFHIAAREGHVDI 322

 Score = 21.9 bits (45), Expect(2) = 2e-07,   Method: Compositional matrix adjust.
 Identities = 13/38 (34%), Positives = 21/38 (55%), Gaps = 1/38 (2%)
 Frame = +3

Query: 326 RLLLQYNAEIDDITL-DHLTPLHVAAHCGHHRVAKVLL 362
           + LL  NA + +++  +  TPLH AA  GH    + +L
Sbjct: 327 KTLLASNAGVWNVSSHNSRTPLHTAALHGHSEAVRFML 440

 Score = 52.4 bits (124), Expect = 2e-06,   Method: Composition-based stats.
 Identities = 28/91 (30%), Positives = 44/91 (48%)
 Frame = +2

Query: 302 IQAKTKNGLSPIHMAAQGDHLDCVRLLLQYNAEIDDITLDHLTPLHVAAHCGHHRVAKVL 361
           +Q     G  P+H  AQ   LDC+  LLQ   ++D +     TPL +A       V  +L
Sbjct: 56  LQIGNFEGKKPLHETAQFGQLDCMNFLLQRGVQVDCLKRADWTPLMLACTKCQLPVISLL 235

Query: 362 LDKGAKPNSRALNGFTPLHIACKKNHIRVME 392
           L  GA P     +G+   HIA ++ H+ +++
Sbjct: 236 LKHGADPALVNKDGWNSFHIAAREGHVDILK 328

 Score = 51.6 bits (122), Expect = 3e-06,   Method: Composition-based stats.
 Identities = 27/96 (28%), Positives = 51/96 (53%)
 Frame = +2

Query: 69  LHKEIILETTTKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHL 128
           L  E+ L+    +G   LH  A  GQ + +  L+  G  V+   +  +TPL +A  +  L
Sbjct: 38  LCDEVDLQIGNFEGKKPLHETAQFGQLDCMNFLLQRGVQVDCLKRADWTPLMLACTKCQL 217

Query: 129 EVVKFLLENGANQNVATEDGFTPLAVALQQGHENVV 164
            V+  LL++GA+  +  +DG+    +A ++GH +++
Sbjct: 218 PVISLLLKHGADPALVNKDGWNSFHIAAREGHVDIL 325

 Score = 51.2 bits (121), Expect = 3e-06,   Method: Composition-based stats.
 Identities = 26/84 (30%), Positives = 44/84 (52%)
 Frame = +2

Query: 243 GITPLHIASRRGNVIMVRLLLDRGAQIETRTKDELTPLHCAARNGHVRISEILLDHGAPI 302
           G  PLH  ++ G +  +  LL RG Q++   + + TPL  A     + +  +LL HGA  
Sbjct: 77  GKKPLHETAQFGQLDCMNFLLQRGVQVDCLKRADWTPLMLACTKCQLPVISLLLKHGADP 256

Query: 303 QAKTKNGLSPIHMAAQGDHLDCVR 326
               K+G +  H+AA+  H+D ++
Sbjct: 257 ALVNKDGWNSFHIAAREGHVDILK 328

 Score = 50.1 bits (118), Expect = 9e-06,   Method: Composition-based stats.
 Identities = 24/85 (28%), Positives = 43/85 (50%)
 Frame = +2

Query: 638 QGVTPLHLAAQEGHTEMVALLLSKQANGNLGNKSGLTPLHLVSQEGHVPVADVLIKHGVT 697
           +G  PLH  AQ G  + +  LL +    +   ++  TPL L   +  +PV  +L+KHG  
Sbjct: 74  EGKKPLHETAQFGQLDCMNFLLQRGVQVDCLKRADWTPLMLACTKCQLPVISLLLKHGAD 253

Query: 698 VDATTRMGYTPLHVASHYGNIKLVK 722
                + G+   H+A+  G++ ++K
Sbjct: 254 PALVNKDGWNSFHIAAREGHVDILK 328

 Score = 48.5 bits (114), Expect(2) = 1e-05,   Method: Composition-based stats.
 Identities = 23/86 (26%), Positives = 43/86 (50%)
 Frame = +2

Query: 539 KGFTPLHVAAKYGKVRLAELLLEHDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGS 598
           +G  PLH  A++G++     LL+     +   +   TPL +A     L ++ LLL  G  
Sbjct: 74  EGKKPLHETAQFGQLDCMNFLLQRGVQVDCLKRADWTPLMLACTKCQLPVISLLLKHGAD 253

Query: 599 PHSPAWNGYTPLHIAAKQNQIEVARS 624
           P     +G+   HIAA++  +++ ++
Sbjct: 254 PALVNKDGWNSFHIAAREGHVDILKN 331

 Score = 20.4 bits (41), Expect(2) = 1e-05,   Method: Compositional matrix adjust.
 Identities = 10/28 (35%), Positives = 14/28 (50%)
 Frame = +3

Query: 657 LLLSKQANGNLGNKSGLTPLHLVSQEGH 684
           LL S     N+ + +  TPLH  +  GH
Sbjct: 333 LLASNAGVWNVSSHNSRTPLHTAALHGH 416

 Score = 47.0 bits (110), Expect = 7e-05,   Method: Composition-based stats.
 Identities = 26/83 (31%), Positives = 39/83 (46%)
 Frame = +2

Query: 573 GLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQIEVARSLLQYGGSA 632
           G  PLH       LD +  LL RG          +TPL +A  + Q+ V   LL++G   
Sbjct: 77  GKKPLHETAQFGQLDCMNFLLQRGVQVDCLKRADWTPLMLACTKCQLPVISLLLKHGADP 256

Query: 633 NAESVQGVTPLHLAAQEGHTEMV 655
              +  G    H+AA+EGH +++
Sbjct: 257 ALVNKDGWNSFHIAAREGHVDIL 325

 Score = 45.8 bits (107), Expect = 1e-04,   Method: Composition-based stats.
 Identities = 27/86 (31%), Positives = 36/86 (41%)
 Frame = +2

Query: 436 VSNVKVETPLHMAARAGHTEVXXXXXXXXXXXXXXXXXXXTPLHCAARIGHTGMVKLLLE 495
           + N + + PLH  A+ G  +                    TPL  A       ++ LLL+
Sbjct: 62  IGNFEGKKPLHETAQFGQLDCMNFLLQRGVQVDCLKRADWTPLMLACTKCQLPVISLLLK 241

Query: 496 NGASPNLATTAGHTPLHTAAREGHVD 521
           +GA P L    G    H AAREGHVD
Sbjct: 242 HGADPALVNKDGWNSFHIAAREGHVD 319

 Score = 41.2 bits (95), Expect(2) = 0.001,   Method: Composition-based stats.
 Identities = 26/80 (32%), Positives = 37/80 (46%)
 Frame = +2

Query: 181 LHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFTP 240
           LH  A+         LLQ     D L +  +TPL +A     L V  LLL  GA      
Sbjct: 89  LHETAQFGQLDCMNFLLQRGVQVDCLKRADWTPLMLACTKCQLPVISLLLKHGADPALVN 268

Query: 241 QNGITPLHIASRRGNVIMVR 260
           ++G    HIA+R G+V +++
Sbjct: 269 KDGWNSFHIAAREGHVDILK 328

 Score = 21.2 bits (43), Expect(2) = 0.001,   Method: Compositional matrix adjust.
 Identities = 9/19 (47%), Positives = 11/19 (57%)
 Frame = +3

Query: 278 TPLHCAARNGHVRISEILL 296
           TPLH AA +GH      +L
Sbjct: 384 TPLHTAALHGHSEAVRFML 440

 Score = 41.6 bits (96), Expect = 0.003,   Method: Composition-based stats.
 Identities = 24/77 (31%), Positives = 35/77 (45%)
 Frame = +2

Query: 477 PLHCAARIGHTGMVKLLLENGASPNLATTAGHTPLHTAAREGHVDTALALLEKEASQACM 536
           PLH  A+ G    +  LL+ G   +    A  TPL  A  +  +     LL+  A  A +
Sbjct: 86  PLHETAQFGQLDCMNFLLQRGVQVDCLKRADWTPLMLACTKCQLPVISLLLKHGADPALV 265

Query: 537 TKKGFTPLHVAAKYGKV 553
            K G+   H+AA+ G V
Sbjct: 266 NKDGWNSFHIAAREGHV 316

 Score = 38.1 bits (87), Expect = 0.031,   Method: Composition-based stats.
 Identities = 22/81 (27%), Positives = 36/81 (44%)
 Frame = +2

Query: 279 PLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYNAEIDDI 338
           PLH  A+ G +     LL  G  +    +   +P+ +A     L  + LLL++ A+   +
Sbjct: 86  PLHETAQFGQLDCMNFLLQRGVQVDCLKRADWTPLMLACTKCQLPVISLLLKHGADPALV 265

Query: 339 TLDHLTPLHVAAHCGHHRVAK 359
             D     H+AA  GH  + K
Sbjct: 266 NKDGWNSFHIAAREGHVDILK 328

 Score = 36.2 bits (82), Expect = 0.14,   Method: Composition-based stats.
 Identities = 26/112 (23%), Positives = 49/112 (43%)
 Frame = +2

Query: 114 KGFTPLYMAAQENHLEVVKFLLENGANQNVATEDGFTPLAVALQQGHENVVAHLINYGTK 173
           +G  PL+  AQ   L+ + FLL+ G   +      +TPL +A                  
Sbjct: 74  EGKKPLHETAQFGQLDCMNFLLQRGVQVDCLKRADWTPLMLACT---------------- 205

Query: 174 GKVRLPALHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNV 225
            K +LP +            ++LL++  +P +++K G+   HIAA   ++++
Sbjct: 206 -KCQLPVI------------SLLLKHGADPALVNKDGWNSFHIAAREGHVDI 322

 Score = 33.5 bits (75), Expect = 0.91,   Method: Composition-based stats.
 Identities = 12/30 (40%), Positives = 21/30 (70%)
 Frame = +2

Query: 36  LRNGVDINTCNQNGLNGLHLASKEGHVKMV 65
           L++G D    N++G N  H+A++EGHV ++
Sbjct: 236 LKHGADPALVNKDGWNSFHIAAREGHVDIL 325
>20884
          Length = 712

 Score = 53.1 bits (126), Expect(2) = 2e-10,   Method: Compositional matrix adjust.
 Identities = 39/118 (33%), Positives = 59/118 (50%), Gaps = 4/118 (3%)
 Frame = +1

Query: 571 KNGLTPLHVAVHHNNLDIVKLLLPRGGSP---HSPAWNGYTPLHIAAKQNQIEVARSLLQ 627
           ++G + LH+++ H   D+   ++    SP   + P     TPLH+A    Q+ V R L+ 
Sbjct: 184 EDGDSYLHMSIIHLLPDVSLKVISVAPSPDYINIPNMLHQTPLHLAVATRQMWVVRRLMV 363

Query: 628 YGGSANAESVQGVTPLHLAAQEGHTEMVALLLSK-QANGNLGNKSGLTPLHLVSQEGH 684
            G +  A    G T LH+A +EG TEMV LLL+  Q    L N+  L  L +    G+
Sbjct: 364 AGAAMEAPDYCGNTALHIACREGMTEMVKLLLTPVQYQETLANQYSLPQLTISPGPGY 537

 Score = 31.6 bits (70), Expect(2) = 2e-10,   Method: Compositional matrix adjust.
 Identities = 19/54 (35%), Positives = 31/54 (57%), Gaps = 1/54 (1%)
 Frame = +2

Query: 705 GYTPLHVASHYGNIKLVKFLLQHQADVNAKT-KLGYSPLHQAAQQGHTDIVTLL 757
           GYT  H+A   G++ ++  LL+  A++N +  K G + LH AA  G+   + LL
Sbjct: 551 GYTCAHLALQTGHLHILPLLLERGANINEQDGKSGRTLLHMAADLGYLQALELL 712

 Score = 41.2 bits (95), Expect(2) = 1e-07,   Method: Compositional matrix adjust.
 Identities = 24/62 (38%), Positives = 35/62 (56%), Gaps = 1/62 (1%)
 Frame = +2

Query: 730 DVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGASPNEV-SSNGTTPLAIAKRLGYISVTD 788
           D+  +   GY+  H A Q GH  I+ LLL+ GA+ NE    +G T L +A  LGY+   +
Sbjct: 527 DLAIRNYEGYTCAHLALQTGHLHILPLLLERGANINEQDGKSGRTLLHMAADLGYLQALE 706

Query: 789 VL 790
           +L
Sbjct: 707 LL 712

 Score = 34.7 bits (78), Expect(2) = 1e-07,   Method: Compositional matrix adjust.
 Identities = 21/60 (35%), Positives = 29/60 (48%)
 Frame = +1

Query: 666 NLGNKSGLTPLHLVSQEGHVPVADVLIKHGVTVDATTRMGYTPLHVASHYGNIKLVKFLL 725
           N+ N    TPLHL      + V   L+  G  ++A    G T LH+A   G  ++VK LL
Sbjct: 280 NIPNMLHQTPLHLAVATRQMWVVRRLMVAGAAMEAPDYCGNTALHIACREGMTEMVKLLL 459

 Score = 37.0 bits (84), Expect(2) = 2e-06,   Method: Compositional matrix adjust.
 Identities = 20/54 (37%), Positives = 29/54 (53%)
 Frame = +1

Query: 342 HLTPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHIRVMELLL 395
           H TPLH+A       V + L+  GA   +    G T LHIAC++    +++LLL
Sbjct: 298 HQTPLHLAVATRQMWVVRRLMVAGAAMEAPDYCGNTALHIACREGMTEMVKLLL 459

 Score = 34.3 bits (77), Expect(2) = 2e-06,   Method: Compositional matrix adjust.
 Identities = 22/49 (44%), Positives = 29/49 (59%), Gaps = 1/49 (2%)
 Frame = +2

Query: 408 GLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKV-ETPLHMAARAGHTE 455
           G T  H+A   GHL I+  LL+RGA+ N  + K   T LHMAA  G+ +
Sbjct: 551 GYTCAHLALQTGHLHILPLLLERGANINEQDGKSGRTLLHMAADLGYLQ 697

 Score = 33.5 bits (75), Expect(2) = 1e-04,   Method: Compositional matrix adjust.
 Identities = 21/61 (34%), Positives = 31/61 (50%)
 Frame = +1

Query: 245 TPLHIASRRGNVIMVRLLLDRGAQIETRTKDELTPLHCAARNGHVRISEILLDHGAPIQA 304
           TPLH+A     + +VR L+  GA +E       T LH A R G   + ++LL    P+Q 
Sbjct: 304 TPLHLAVATRQMWVVRRLMVAGAAMEAPDYCGNTALHIACREGMTEMVKLLL---TPVQY 474

Query: 305 K 305
           +
Sbjct: 475 Q 477

 Score = 32.0 bits (71), Expect(2) = 1e-04,   Method: Compositional matrix adjust.
 Identities = 18/52 (34%), Positives = 30/52 (57%), Gaps = 1/52 (1%)
 Frame = +2

Query: 344 TPLHVAAHCGHHRVAKVLLDKGAKPNSR-ALNGFTPLHIACKKNHIRVMELL 394
           T  H+A   GH  +  +LL++GA  N +   +G T LH+A    +++ +ELL
Sbjct: 557 TCAHLALQTGHLHILPLLLERGANINEQDGKSGRTLLHMAADLGYLQALELL 712

 Score = 33.5 bits (75), Expect(2) = 2e-04,   Method: Compositional matrix adjust.
 Identities = 31/93 (33%), Positives = 40/93 (43%), Gaps = 4/93 (4%)
 Frame = +1

Query: 406 ESGLTPLHVASFMGHLPIVK-NLLQRGASP---NVSNVKVETPLHMAARAGHTEVXXXXX 461
           E G + LH+ S +  LP V   ++    SP   N+ N+  +TPLH+A       V     
Sbjct: 184 EDGDSYLHM-SIIHLLPDVSLKVISVAPSPDYINIPNMLHQTPLHLAVATRQMWVVRRLM 360

Query: 462 XXXXXXXXXXXXXXTPLHCAARIGHTGMVKLLL 494
                         T LH A R G T MVKLLL
Sbjct: 361 VAGAAMEAPDYCGNTALHIACREGMTEMVKLLL 459

 Score = 31.2 bits (69), Expect(2) = 2e-04,   Method: Compositional matrix adjust.
 Identities = 22/60 (36%), Positives = 33/60 (55%), Gaps = 1/60 (1%)
 Frame = +2

Query: 534 ACMTKKGFTPLHVAAKYGKVRLAELLLEHDAHPNAA-GKNGLTPLHVAVHHNNLDIVKLL 592
           A    +G+T  H+A + G + +  LLLE  A+ N   GK+G T LH+A     L  ++LL
Sbjct: 533 AIRNYEGYTCAHLALQTGHLHILPLLLERGANINEQDGKSGRTLLHMAADLGYLQALELL 712

 Score = 32.7 bits (73), Expect(2) = 4e-04,   Method: Compositional matrix adjust.
 Identities = 22/62 (35%), Positives = 29/62 (46%)
 Frame = +1

Query: 42  INTCNQNGLNGLHLASKEGHVKMVVELLHKEIILETTTKKGNTALHIAALAGQDEVVREL 101
           IN  N      LHLA     + +V  L+     +E     GNTALHIA   G  E+V+ L
Sbjct: 277 INIPNMLHQTPLHLAVATRQMWVVRRLMVAGAAMEAPDYCGNTALHIACREGMTEMVKLL 456

Query: 102 VN 103
           + 
Sbjct: 457 LT 462

 Score = 30.8 bits (68), Expect(2) = 4e-04,   Method: Compositional matrix adjust.
 Identities = 13/32 (40%), Positives = 21/32 (65%)
 Frame = +2

Query: 111 QSQKGFTPLYMAAQENHLEVVKFLLENGANQN 142
           ++ +G+T  ++A Q  HL ++  LLE GAN N
Sbjct: 539 RNYEGYTCAHLALQTGHLHILPLLLERGANIN 634

 Score = 38.1 bits (87), Expect(2) = 0.001,   Method: Compositional matrix adjust.
 Identities = 21/58 (36%), Positives = 37/58 (63%), Gaps = 1/58 (1%)
 Frame = +2

Query: 371 RALNGFTPLHIACKKNHIRVMELLLKTGASIDAVT-ESGLTPLHVASFMGHLPIVKNL 427
           R   G+T  H+A +  H+ ++ LLL+ GA+I+    +SG T LH+A+ +G+L  ++ L
Sbjct: 539 RNYEGYTCAHLALQTGHLHILPLLLERGANINEQDGKSGRTLLHMAADLGYLQALELL 712

 Score = 23.9 bits (50), Expect(2) = 0.001,   Method: Compositional matrix adjust.
 Identities = 15/52 (28%), Positives = 25/52 (48%)
 Frame = +1

Query: 311 SPIHMAAQGDHLDCVRLLLQYNAEIDDITLDHLTPLHVAAHCGHHRVAKVLL 362
           +P+H+A     +  VR L+   A ++       T LH+A   G   + K+LL
Sbjct: 304 TPLHLAVATRQMWVVRRLMVAGAAMEAPDYCGNTALHIACREGMTEMVKLLL 459

 Score = 31.2 bits (69), Expect(2) = 0.002,   Method: Compositional matrix adjust.
 Identities = 18/56 (32%), Positives = 31/56 (55%), Gaps = 1/56 (1%)
 Frame = +2

Query: 604 WNGYTPLHIAAKQNQIEVARSLLQYGGSANAESVQ-GVTPLHLAAQEGHTEMVALL 658
           + GYT  H+A +   + +   LL+ G + N +  + G T LH+AA  G+ + + LL
Sbjct: 545 YEGYTCAHLALQTGHLHILPLLLERGANINEQDGKSGRTLLHMAADLGYLQALELL 712

 Score = 29.6 bits (65), Expect(2) = 0.002,   Method: Compositional matrix adjust.
 Identities = 18/52 (34%), Positives = 26/52 (50%)
 Frame = +1

Query: 542 TPLHVAAKYGKVRLAELLLEHDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLL 593
           TPLH+A    ++ +   L+   A   A    G T LH+A      ++VKLLL
Sbjct: 304 TPLHLAVATRQMWVVRRLMVAGAAMEAPDYCGNTALHIACREGMTEMVKLLL 459

 Score = 41.2 bits (95), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 25/66 (37%), Positives = 35/66 (53%), Gaps = 3/66 (4%)
 Frame = +1

Query: 201 PNPDVLSKTGF---TPLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVI 257
           P+PD ++       TPLH+A     + V + L+  GA++      G T LHIA R G   
Sbjct: 262 PSPDYINIPNMLHQTPLHLAVATRQMWVVRRLMVAGAAMEAPDYCGNTALHIACREGMTE 441

Query: 258 MVRLLL 263
           MV+LLL
Sbjct: 442 MVKLLL 459

 Score = 36.6 bits (83), Expect(2) = 0.005,   Method: Compositional matrix adjust.
 Identities = 26/65 (40%), Positives = 33/65 (50%), Gaps = 6/65 (9%)
 Frame = +1

Query: 83  NTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLL------E 136
            T LH+A    Q  VVR L+  GA + A    G T L++A +E   E+VK LL      E
Sbjct: 301 QTPLHLAVATRQMWVVRRLMVAGAAMEAPDYCGNTALHIACREGMTEMVKLLLTPVQYQE 480

Query: 137 NGANQ 141
             ANQ
Sbjct: 481 TLANQ 495

 Score = 23.1 bits (48), Expect(2) = 0.005,   Method: Compositional matrix adjust.
 Identities = 15/48 (31%), Positives = 24/48 (50%), Gaps = 5/48 (10%)
 Frame = +2

Query: 143 VATEDGFTPLAVALQQGHENVVAHLINYGTK-----GKVRLPALHIAA 185
           +   +G+T   +ALQ GH +++  L+  G       GK     LH+AA
Sbjct: 536 IRNYEGYTCAHLALQTGHLHILPLLLERGANINEQDGKSGRTLLHMAA 679

 Score = 36.6 bits (83), Expect = 0.10,   Method: Compositional matrix adjust.
 Identities = 22/57 (38%), Positives = 33/57 (57%), Gaps = 1/57 (1%)
 Frame = +2

Query: 636 SVQGVTPLHLAAQEGHTEMVALLLSKQANGN-LGNKSGLTPLHLVSQEGHVPVADVL 691
           + +G T  HLA Q GH  ++ LLL + AN N    KSG T LH+ +  G++   ++L
Sbjct: 542 NYEGYTCAHLALQTGHLHILPLLLERGANINEQDGKSGRTLLHMAADLGYLQALELL 712

 Score = 35.0 bits (79), Expect = 0.25,   Method: Compositional matrix adjust.
 Identities = 20/52 (38%), Positives = 29/52 (55%)
 Frame = +1

Query: 377 TPLHIACKKNHIRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLL 428
           TPLH+A     + V+  L+  GA+++A    G T LH+A   G   +VK LL
Sbjct: 304 TPLHLAVATRQMWVVRRLMVAGAAMEAPDYCGNTALHIACREGMTEMVKLLL 459

 Score = 26.9 bits (58), Expect(2) = 0.46,   Method: Compositional matrix adjust.
 Identities = 17/60 (28%), Positives = 25/60 (41%)
 Frame = +1

Query: 501 NLATTAGHTPLHTAAREGHVDTALALLEKEASQACMTKKGFTPLHVAAKYGKVRLAELLL 560
           N+      TPLH A     +     L+   A+       G T LH+A + G   + +LLL
Sbjct: 280 NIPNMLHQTPLHLAVATRQMWVVRRLMVAGAAMEAPDYCGNTALHIACREGMTEMVKLLL 459

 Score = 26.2 bits (56), Expect(2) = 0.46,   Method: Compositional matrix adjust.
 Identities = 17/43 (39%), Positives = 25/43 (58%), Gaps = 1/43 (2%)
 Frame = +2

Query: 573 GLTPLHVAVHHNNLDIVKLLLPRGGSPHSP-AWNGYTPLHIAA 614
           G T  H+A+   +L I+ LLL RG + +     +G T LH+AA
Sbjct: 551 GYTCAHLALQTGHLHILPLLLERGANINEQDGKSGRTLLHMAA 679

 Score = 33.5 bits (75), Expect = 0.88,   Method: Compositional matrix adjust.
 Identities = 24/78 (30%), Positives = 40/78 (51%), Gaps = 1/78 (1%)
 Frame = +1

Query: 707 TPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGASPNE 766
           TPLH+A     + +V+ L+   A + A    G + LH A ++G T++V LLL        
Sbjct: 304 TPLHLAVATRQMWVVRRLMVAGAAMEAPDYCGNTALHIACREGMTEMVKLLLTPVQYQET 483

Query: 767 VSSNGTTP-LAIAKRLGY 783
           +++  + P L I+   GY
Sbjct: 484 LANQYSLPQLTISPGPGY 537

 Score = 33.1 bits (74), Expect = 0.95,   Method: Compositional matrix adjust.
 Identities = 21/61 (34%), Positives = 32/61 (52%), Gaps = 1/61 (1%)
 Frame = +2

Query: 75  LETTTKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQK-GFTPLYMAAQENHLEVVKF 133
           L     +G T  H+A   G   ++  L+  GAN+N Q  K G T L+MAA   +L+ ++ 
Sbjct: 530 LAIRNYEGYTCAHLALQTGHLHILPLLLERGANINEQDGKSGRTLLHMAADLGYLQALEL 709

Query: 134 L 134
           L
Sbjct: 710 L 712

 Score = 33.1 bits (74), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 22/54 (40%), Positives = 33/54 (61%), Gaps = 1/54 (1%)
 Frame = +2

Query: 243 GITPLHIASRRGNVIMVRLLLDRGAQI-ETRTKDELTPLHCAARNGHVRISEIL 295
           G T  H+A + G++ ++ LLL+RGA I E   K   T LH AA  G+++  E+L
Sbjct: 551 GYTCAHLALQTGHLHILPLLLERGANINEQDGKSGRTLLHMAADLGYLQALELL 712

 Score = 32.0 bits (71), Expect = 2.3,   Method: Compositional matrix adjust.
 Identities = 20/54 (37%), Positives = 33/54 (61%), Gaps = 1/54 (1%)
 Frame = +2

Query: 210 GFTPLHIAAHYENLNVAQLLLNRGASVNFTP-QNGITPLHIASRRGNVIMVRLL 262
           G+T  H+A    +L++  LLL RGA++N    ++G T LH+A+  G +  + LL
Sbjct: 551 GYTCAHLALQTGHLHILPLLLERGANINEQDGKSGRTLLHMAADLGYLQALELL 712
>15772
          Length = 1282

 Score = 62.4 bits (150), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 37/91 (40%), Positives = 45/91 (49%)
 Frame = -3

Query: 245  TPLHIASRRGNVIMVRLLLDRGAQIETRTKDELTPLHCAARNGHVRISEILLDHGAPIQA 304
            T LH A ++G V  +RLLLD GA+   RT    TP HCAA    V     L     P+  
Sbjct: 1172 TALHWACQKGFVECIRLLLDHGAKGTARTDTGWTPAHCAAECNRVTALRALHAALVPVDL 993

Query: 305  KTKNGLSPIHMAAQGDHLDCVRLLLQYNAEI 335
              K G +P  +A    H DC R LLQ  AE+
Sbjct: 992  TDKYGDTPRRIATLYGHRDCARYLLQAEAEV 900

 Score = 60.8 bits (146), Expect = 4e-09,   Method: Compositional matrix adjust.
 Identities = 34/98 (34%), Positives = 49/98 (50%)
 Frame = -3

Query: 641  TPLHLAAQEGHTEMVALLLSKQANGNLGNKSGLTPLHLVSQEGHVPVADVLIKHGVTVDA 700
            T LH A Q+G  E + LLL   A G     +G TP H  ++   V     L    V VD 
Sbjct: 1172 TALHWACQKGFVECIRLLLDHGAKGTARTDTGWTPAHCAAECNRVTALRALHAALVPVDL 993

Query: 701  TTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLG 738
            T + G TP  +A+ YG+    ++LLQ +A+V  + + G
Sbjct: 992  TDKYGDTPRRIATLYGHRDCARYLLQAEAEVAERRRKG 879

 Score = 55.5 bits (132), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 31/99 (31%), Positives = 46/99 (46%)
 Frame = -3

Query: 331  YNAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHIRV 390
            Y+  + D    + T LH A   G     ++LLD GAK  +R   G+TP H A + N +  
Sbjct: 1211 YDVNLKDPDAGNKTALHWACQKGFVECIRLLLDHGAKGTARTDTGWTPAHCAAECNRVTA 1032

Query: 391  MELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQ 429
            +  L      +D   + G TP  +A+  GH    + LLQ
Sbjct: 1031 LRALHAALVPVDLTDKYGDTPRRIATLYGHRDCARYLLQ 915

 Score = 49.7 bits (117), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 33/106 (31%), Positives = 45/106 (42%)
 Frame = -3

Query: 666  NLGNKSGLTPLHLVSQEGHVPVADVLIKHGVTVDATTRMGYTPLHVASHYGNIKLVKFLL 725
            + GNK   T LH   Q+G V    +L+ HG    A T  G+TP H A+    +  ++ L 
Sbjct: 1187 DAGNK---TALHWACQKGFVECIRLLLDHGAKGTARTDTGWTPAHCAAECNRVTALRALH 1017

Query: 726  QHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGASPNEVSSNG 771
                 V+   K G +P   A   GH D    LL+  A   E    G
Sbjct: 1016 AALVPVDLTDKYGDTPRRIATLYGHRDCARYLLQAEAEVAERRRKG 879

 Score = 46.6 bits (109), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 28/88 (31%), Positives = 47/88 (53%), Gaps = 1/88 (1%)
 Frame = -3

Query: 82   GN-TALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGAN 140
            GN TALH A   G  E +R L+++GA   A++  G+TP + AA+ N +  ++ L      
Sbjct: 1181 GNKTALHWACQKGFVECIRLLLDHGAKGTARTDTGWTPAHCAAECNRVTALRALHAALVP 1002

Query: 141  QNVATEDGFTPLAVALQQGHENVVAHLI 168
             ++  + G TP  +A   GH +   +L+
Sbjct: 1001 VDLTDKYGDTPRRIATLYGHRDCARYLL 918

 Score = 44.3 bits (103), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 24/80 (30%), Positives = 40/80 (50%)
 Frame = -3

Query: 377  TPLHIACKKNHIRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPNV 436
            T LH AC+K  +  + LLL  GA   A T++G TP H A+    +  ++ L       ++
Sbjct: 1172 TALHWACQKGFVECIRLLLDHGAKGTARTDTGWTPAHCAAECNRVTALRALHAALVPVDL 993

Query: 437  SNVKVETPLHMAARAGHTEV 456
            ++   +TP  +A   GH + 
Sbjct: 992  TDKYGDTPRRIATLYGHRDC 933

 Score = 42.0 bits (97), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 36/136 (26%), Positives = 50/136 (36%), Gaps = 6/136 (4%)
 Frame = -3

Query: 412  LHVASFMGHLPIVKNLLQRG------ASPNVSNVKVETPLHMAARAGHTEVXXXXXXXXX 465
            LH A+  G    +++ ++ G        P+  N   +T LH A + G  E          
Sbjct: 1274 LHDAASTGDYDALEDYVKSGIYDVNLKDPDAGN---KTALHWACQKGFVECIRLLLDHGA 1104

Query: 466  XXXXXXXXXXTPLHCAARIGHTGMVKLLLENGASPNLATTAGHTPLHTAAREGHVDTALA 525
                      TP HCAA       ++ L       +L    G TP   A   GH D A  
Sbjct: 1103 KGTARTDTGWTPAHCAAECNRVTALRALHAALVPVDLTDKYGDTPRRIATLYGHRDCARY 924

Query: 526  LLEKEASQACMTKKGF 541
            LL+ EA  A   +KG 
Sbjct: 923  LLQAEAEVAERRRKGL 876

 Score = 39.3 bits (90), Expect = 0.014,   Method: Compositional matrix adjust.
 Identities = 28/98 (28%), Positives = 42/98 (42%)
 Frame = -3

Query: 180  ALHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFT 239
            ALH A +        +LL +       + TG+TP H AA    +   + L      V+ T
Sbjct: 1169 ALHWACQKGFVECIRLLLDHGAKGTARTDTGWTPAHCAAECNRVTALRALHAALVPVDLT 990

Query: 240  PQNGITPLHIASRRGNVIMVRLLLDRGAQIETRTKDEL 277
             + G TP  IA+  G+    R LL   A++  R +  L
Sbjct: 989  DKYGDTPRRIATLYGHRDCARYLLQAEAEVAERRRKGL 876

 Score = 38.1 bits (87), Expect = 0.029,   Method: Compositional matrix adjust.
 Identities = 29/86 (33%), Positives = 35/86 (40%)
 Frame = -3

Query: 542  TPLHVAAKYGKVRLAELLLEHDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHS 601
            T LH A + G V    LLL+H A   A    G TP H A   N +  ++ L         
Sbjct: 1172 TALHWACQKGFVECIRLLLDHGAKGTARTDTGWTPAHCAAECNRVTALRALHAALVPVDL 993

Query: 602  PAWNGYTPLHIAAKQNQIEVARSLLQ 627
                G TP  IA      + AR LLQ
Sbjct: 992  TDKYGDTPRRIATLYGHRDCARYLLQ 915
>28494
          Length = 463

 Score = 61.6 bits (148), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 32/86 (37%), Positives = 46/86 (53%)
 Frame = -1

Query: 295 LLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYNAEIDDITLDHLTPLHVAAHCGH 354
           LL+ GA I     +GL+ +H A   D+LD V  L++ NA++D    +  TPLH  A CG 
Sbjct: 262 LLERGADINTANVDGLTALHQACIDDNLDMVEFLVEQNADVDVCDNEGWTPLHATASCGF 83

Query: 355 HRVAKVLLDKGAKPNSRALNGFTPLH 380
             +A+ LL+ GA    R    + P H
Sbjct: 82  TEIARYLLENGANGGCRQQR-WGPCH 8

 Score = 56.6 bits (135), Expect = 8e-08,   Method: Compositional matrix adjust.
 Identities = 27/73 (36%), Positives = 42/73 (57%)
 Frame = -1

Query: 691 LIKHGVTVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGH 750
           L++ G  ++     G T LH A    N+ +V+FL++  ADV+     G++PLH  A  G 
Sbjct: 262 LLERGADINTANVDGLTALHQACIDDNLDMVEFLVEQNADVDVCDNEGWTPLHATASCGF 83

Query: 751 TDIVTLLLKNGAS 763
           T+I   LL+NGA+
Sbjct: 82  TEIARYLLENGAN 44

 Score = 54.7 bits (130), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 41/136 (30%), Positives = 55/136 (40%)
 Frame = -1

Query: 5   PRRSGSDPAADAATSFLRAARSGNLDKALDHLRNGVDINTCNQNGLNGLHLASKEGHVKM 64
           PR S           FL A  SG+ D+    L  G DINT N +GL              
Sbjct: 352 PRPSAKKVKFQDGCVFLAACSSGDRDEVKKLLERGADINTANVDGL-------------- 215

Query: 65  VVELLHKEIILETTTKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQ 124
                              TALH A +    ++V  LV   A+V+    +G+TPL+  A 
Sbjct: 214 -------------------TALHQACIDDNLDMVEFLVEQNADVDVCDNEGWTPLHATAS 92

Query: 125 ENHLEVVKFLLENGAN 140
               E+ ++LLENGAN
Sbjct: 91  CGFTEIARYLLENGAN 44

 Score = 53.9 bits (128), Expect = 5e-07,   Method: Compositional matrix adjust.
 Identities = 27/99 (27%), Positives = 50/99 (50%)
 Frame = -1

Query: 646 AAQEGHTEMVALLLSKQANGNLGNKSGLTPLHLVSQEGHVPVADVLIKHGVTVDATTRMG 705
           A   G  + V  LL + A+ N  N  GLT LH    + ++ + + L++    VD     G
Sbjct: 298 ACSSGDRDEVKKLLERGADINTANVDGLTALHQACIDDNLDMVEFLVEQNADVDVCDNEG 119

Query: 706 YTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQ 744
           +TPLH  +  G  ++ ++LL++ A+   + +  + P H+
Sbjct: 118 WTPLHATASCGFTEIARYLLENGANGGCRQQR-WGPCHR 5

 Score = 52.8 bits (125), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 32/85 (37%), Positives = 42/85 (49%)
 Frame = -1

Query: 481 AARIGHTGMVKLLLENGASPNLATTAGHTPLHTAAREGHVDTALALLEKEASQACMTKKG 540
           A   G    VK LLE GA  N A   G T LH A  + ++D    L+E+ A       +G
Sbjct: 298 ACSSGDRDEVKKLLERGADINTANVDGLTALHQACIDDNLDMVEFLVEQNADVDVCDNEG 119

Query: 541 FTPLHVAAKYGKVRLAELLLEHDAH 565
           +TPLH  A  G   +A  LLE+ A+
Sbjct: 118 WTPLHATASCGFTEIARYLLENGAN 44

 Score = 52.8 bits (125), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 32/86 (37%), Positives = 42/86 (48%)
 Frame = -1

Query: 559 LLEHDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQ 618
           LLE  A  N A  +GLT LH A   +NLD+V+ L+ +          G+TPLH  A    
Sbjct: 262 LLERGADINTANVDGLTALHQACIDDNLDMVEFLVEQNADVDVCDNEGWTPLHATASCGF 83

Query: 619 IEVARSLLQYGGSANAESVQGVTPLH 644
            E+AR LL+ G +      Q   P H
Sbjct: 82  TEIARYLLENGANGGCRQ-QRWGPCH 8

 Score = 52.8 bits (125), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 27/72 (37%), Positives = 40/72 (55%)
 Frame = -1

Query: 229 LLNRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETRTKDELTPLHCAARNGH 288
           LL RGA +N    +G+T LH A    N+ MV  L+++ A ++    +  TPLH  A  G 
Sbjct: 262 LLERGADINTANVDGLTALHQACIDDNLDMVEFLVEQNADVDVCDNEGWTPLHATASCGF 83

Query: 289 VRISEILLDHGA 300
             I+  LL++GA
Sbjct: 82  TEIARYLLENGA 47

 Score = 48.1 bits (113), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 28/87 (32%), Positives = 41/87 (47%)
 Frame = -1

Query: 579 VAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQIEVARSLLQYGGSANAESVQ 638
            A    + D VK LL RG   ++   +G T LH A   + +++   L++     +    +
Sbjct: 301 AACSSGDRDEVKKLLERGADINTANVDGLTALHQACIDDNLDMVEFLVEQNADVDVCDNE 122

Query: 639 GVTPLHLAAQEGHTEMVALLLSKQANG 665
           G TPLH  A  G TE+   LL   ANG
Sbjct: 121 GWTPLHATASCGFTEIARYLLENGANG 41

 Score = 47.0 bits (110), Expect = 7e-05,   Method: Compositional matrix adjust.
 Identities = 26/75 (34%), Positives = 40/75 (53%)
 Frame = -1

Query: 382 ACKKNHIRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKV 441
           AC       ++ LL+ GA I+     GLT LH A    +L +V+ L+++ A  +V + + 
Sbjct: 298 ACSSGDRDEVKKLLERGADINTANVDGLTALHQACIDDNLDMVEFLVEQNADVDVCDNEG 119

Query: 442 ETPLHMAARAGHTEV 456
            TPLH  A  G TE+
Sbjct: 118 WTPLHATASCGFTEI 74

 Score = 43.9 bits (102), Expect = 6e-04,   Method: Compositional matrix adjust.
 Identities = 34/122 (27%), Positives = 47/122 (38%)
 Frame = -1

Query: 424 VKNLLQRGASPNVSNVKVETPLHMAARAGHTEVXXXXXXXXXXXXXXXXXXXTPLHCAAR 483
           VK LL+RGA  N +NV   T LH A    + +                            
Sbjct: 271 VKKLLERGADINTANVDGLTALHQACIDDNLD---------------------------- 176

Query: 484 IGHTGMVKLLLENGASPNLATTAGHTPLHTAAREGHVDTALALLEKEASQACMTKKGFTP 543
                MV+ L+E  A  ++    G TPLH  A  G  + A  LLE  A+  C  ++ + P
Sbjct: 175 -----MVEFLVEQNADVDVCDNEGWTPLHATASCGFTEIARYLLENGANGGCRQQR-WGP 14

Query: 544 LH 545
            H
Sbjct: 13  CH 8

 Score = 42.4 bits (98), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 24/80 (30%), Positives = 36/80 (45%)
 Frame = -1

Query: 711 VASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGASPNEVSSN 770
            A   G+   VK LL+  AD+N     G + LHQA    + D+V  L++  A  +   + 
Sbjct: 301 AACSSGDRDEVKKLLERGADINTANVDGLTALHQACIDDNLDMVEFLVEQNADVDVCDNE 122

Query: 771 GTTPLAIAKRLGYISVTDVL 790
           G TPL      G+  +   L
Sbjct: 121 GWTPLHATASCGFTEIARYL 62

 Score = 41.2 bits (95), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 31/99 (31%), Positives = 45/99 (45%), Gaps = 4/99 (4%)
 Frame = -1

Query: 141 QNVATEDGFTPLAVALQQGHENVVAHLINYG----TKGKVRLPALHIAARNDDTRTAAVL 196
           + V  +DG   LA A   G  + V  L+  G    T     L ALH A  +D+      L
Sbjct: 337 KKVKFQDGCVFLA-ACSSGDRDEVKKLLERGADINTANVDGLTALHQACIDDNLDMVEFL 161

Query: 197 LQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGAS 235
           ++ + + DV    G+TPLH  A      +A+ LL  GA+
Sbjct: 160 VEQNADVDVCDNEGWTPLHATASCGFTEIARYLLENGAN 44
>38834
          Length = 496

 Score = 60.5 bits (145), Expect = 7e-09,   Method: Composition-based stats.
 Identities = 26/96 (27%), Positives = 55/96 (57%)
 Frame = -1

Query: 678 LVSQEGHVPVADVLIKHGVTVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKL 737
           +    GH+ +A++L + GV ++     GYTP H++ ++    +  FL++  A++N     
Sbjct: 496 IACSSGHLDIAEMLHRRGVQINVVNINGYTPXHLSVYFNKFDITHFLVKINAEINTVNNA 317

Query: 738 GYSPLHQAAQQGHTDIVTLLLKNGASPNEVSSNGTT 773
           G +P++ AA +G++ I+ L++  G   N + S+ +T
Sbjct: 316 GQTPVYLAALRGNSKILALMVNAGCKVNGLVSDIST 209

 Score = 55.1 bits (131), Expect = 3e-07,   Method: Composition-based stats.
 Identities = 26/88 (29%), Positives = 48/88 (54%)
 Frame = -1

Query: 348 VAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHIRVMELLLKTGASIDAVTES 407
           +A   GH  +A++L  +G + N   +NG+TP H++   N   +   L+K  A I+ V  +
Sbjct: 496 IACSSGHLDIAEMLHRRGVQINVVNINGYTPXHLSVYFNKFDITHFLVKINAEINTVNNA 317

Query: 408 GLTPLHVASFMGHLPIVKNLLQRGASPN 435
           G TP+++A+  G+  I+  ++  G   N
Sbjct: 316 GQTPVYLAALRGNSKILALMVNAGCKVN 233

 Score = 53.5 bits (127), Expect = 7e-07,   Method: Composition-based stats.
 Identities = 26/87 (29%), Positives = 48/87 (55%)
 Frame = -1

Query: 283 AARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYNAEIDDITLDH 342
           A  +GH+ I+E+L   G  I     NG +P H++   +  D    L++ NAEI+ +    
Sbjct: 493 ACSSGHLDIAEMLHRRGVQINVVNINGYTPXHLSVYFNKFDITHFLVKINAEINTVNNAG 314

Query: 343 LTPLHVAAHCGHHRVAKVLLDKGAKPN 369
            TP+++AA  G+ ++  ++++ G K N
Sbjct: 313 QTPVYLAALRGNSKILALMVNAGCKVN 233

 Score = 50.8 bits (120), Expect = 5e-06,   Method: Composition-based stats.
 Identities = 25/82 (30%), Positives = 48/82 (58%)
 Frame = -1

Query: 579 VAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQIEVARSLLQYGGSANAESVQ 638
           +A    +LDI ++L  RG   +    NGYTP H++   N+ ++   L++     N  +  
Sbjct: 496 IACSSGHLDIAEMLHRRGVQINVVNINGYTPXHLSVYFNKFDITHFLVKINAEINTVNNA 317

Query: 639 GVTPLHLAAQEGHTEMVALLLS 660
           G TP++LAA  G+++++AL+++
Sbjct: 316 GQTPVYLAALRGNSKILALMVN 251

 Score = 50.4 bits (119), Expect = 6e-06,   Method: Composition-based stats.
 Identities = 23/76 (30%), Positives = 42/76 (55%)
 Frame = -1

Query: 381 IACKKNHIRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVK 440
           IAC   H+ + E+L + G  I+ V  +G TP H++ +     I   L++  A  N  N  
Sbjct: 496 IACSSGHLDIAEMLHRRGVQINVVNINGYTPXHLSVYFNKFDITHFLVKINAEINTVNNA 317

Query: 441 VETPLHMAARAGHTEV 456
            +TP+++AA  G++++
Sbjct: 316 GQTPVYLAALRGNSKI 269

 Score = 48.1 bits (113), Expect = 3e-05,   Method: Composition-based stats.
 Identities = 30/112 (26%), Positives = 56/112 (50%), Gaps = 8/112 (7%)
 Frame = -1

Query: 183 IAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFTPQN 242
           IA  +     A +L +     +V++  G+TP H++ ++   ++   L+   A +N     
Sbjct: 496 IACSSGHLDIAEMLHRRGVQINVVNINGYTPXHLSVYFNKFDITHFLVKINAEINTVNNA 317

Query: 243 GITPLHIASRRGNVIMVRLLLDRGAQ-------IETR-TKDELTPLHCAARN 286
           G TP+++A+ RGN  ++ L+++ G +       I TR  KD L  +   ARN
Sbjct: 316 GQTPVYLAALRGNSKILALMVNAGCKVNGLVSDISTRINKDLLEYIQYLARN 161

 Score = 47.0 bits (110), Expect = 6e-05,   Method: Composition-based stats.
 Identities = 23/86 (26%), Positives = 44/86 (51%)
 Frame = -1

Query: 88  IAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQNVATED 147
           IA  +G  ++   L   G  +N  +  G+TP +++   N  ++  FL++  A  N     
Sbjct: 496 IACSSGHLDIAEMLHRRGVQINVVNINGYTPXHLSVYFNKFDITHFLVKINAEINTVNNA 317

Query: 148 GFTPLAVALQQGHENVVAHLINYGTK 173
           G TP+ +A  +G+  ++A ++N G K
Sbjct: 316 GQTPVYLAALRGNSKILALMVNAGCK 239

 Score = 46.2 bits (108), Expect = 1e-04,   Method: Composition-based stats.
 Identities = 32/114 (28%), Positives = 55/114 (48%), Gaps = 1/114 (0%)
 Frame = -1

Query: 216 IAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETRTKD 275
           IA    +L++A++L  RG  +N    NG TP H++       +   L+   A+I T    
Sbjct: 496 IACSSGHLDIAEMLHRRGVQINVVNINGYTPXHLSVYFNKFDITHFLVKINAEINTVNNA 317

Query: 276 ELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGL-SPIHMAAQGDHLDCVRLL 328
             TP++ AA  G+ +I  ++++ G  +     NGL S I      D L+ ++ L
Sbjct: 316 GQTPVYLAALRGNSKILALMVNAGCKV-----NGLVSDISTRINKDLLEYIQYL 170

 Score = 43.1 bits (100), Expect = 0.001,   Method: Composition-based stats.
 Identities = 22/89 (24%), Positives = 41/89 (46%)
 Frame = -1

Query: 645 LAAQEGHTEMVALLLSKQANGNLGNKSGLTPLHLVSQEGHVPVADVLIKHGVTVDATTRM 704
           +A   GH ++  +L  +    N+ N +G TP HL        +   L+K    ++     
Sbjct: 496 IACSSGHLDIAEMLHRRGVQINVVNINGYTPXHLSVYFNKFDITHFLVKINAEINTVNNA 317

Query: 705 GYTPLHVASHYGNIKLVKFLLQHQADVNA 733
           G TP+++A+  GN K++  ++     VN 
Sbjct: 316 GQTPVYLAALRGNSKILALMVNAGCKVNG 230

 Score = 43.1 bits (100), Expect = 0.001,   Method: Composition-based stats.
 Identities = 23/89 (25%), Positives = 41/89 (46%)
 Frame = -1

Query: 546 VAAKYGKVRLAELLLEHDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWN 605
           +A   G + +AE+L       N    NG TP H++V+ N  DI   L+      ++    
Sbjct: 496 IACSSGHLDIAEMLHRRGVQINVVNINGYTPXHLSVYFNKFDITHFLVKINAEINTVNNA 317

Query: 606 GYTPLHIAAKQNQIEVARSLLQYGGSANA 634
           G TP+++AA +   ++   ++  G   N 
Sbjct: 316 GQTPVYLAALRGNSKILALMVNAGCKVNG 230

 Score = 42.4 bits (98), Expect = 0.002,   Method: Composition-based stats.
 Identities = 25/98 (25%), Positives = 46/98 (46%), Gaps = 5/98 (5%)
 Frame = -1

Query: 612 IAAKQNQIEVARSLLQYGGSANAESVQGVTPLHLAAQEGHTEMVALLLSKQANGNLGNKS 671
           IA     +++A  L + G   N  ++ G TP HL+      ++   L+   A  N  N +
Sbjct: 496 IACSSGHLDIAEMLHRRGVQINVVNINGYTPXHLSVYFNKFDITHFLVKINAEINTVNNA 317

Query: 672 GLTPLHLVSQEGHVPVADVLIKHGVTV-----DATTRM 704
           G TP++L +  G+  +  +++  G  V     D +TR+
Sbjct: 316 GQTPVYLAALRGNSKILALMVNAGCKVNGLVSDISTRI 203

 Score = 42.4 bits (98), Expect = 0.002,   Method: Composition-based stats.
 Identities = 22/83 (26%), Positives = 39/83 (46%)
 Frame = -1

Query: 514 AAREGHVDTALALLEKEASQACMTKKGFTPLHVAAKYGKVRLAELLLEHDAHPNAAGKNG 573
           A   GH+D A  L  +      +   G+TP H++  + K  +   L++ +A  N     G
Sbjct: 493 ACSSGHLDIAEMLHRRGVQINVVNINGYTPXHLSVYFNKFDITHFLVKINAEINTVNNAG 314

Query: 574 LTPLHVAVHHNNLDIVKLLLPRG 596
            TP+++A    N  I+ L++  G
Sbjct: 313 QTPVYLAALRGNSKILALMVNAG 245

 Score = 40.4 bits (93), Expect = 0.007,   Method: Composition-based stats.
 Identities = 18/90 (20%), Positives = 46/90 (51%)
 Frame = -1

Query: 315 MAAQGDHLDCVRLLLQYNAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRALN 374
           +A    HLD   +L +   +I+ + ++  TP H++ +     +   L+   A+ N+    
Sbjct: 496 IACSSGHLDIAEMLHRRGVQINVVNINGYTPXHLSVYFNKFDITHFLVKINAEINTVNNA 317

Query: 375 GFTPLHIACKKNHIRVMELLLKTGASIDAV 404
           G TP+++A  + + +++ L++  G  ++ +
Sbjct: 316 GQTPVYLAALRGNSKILALMVNAGCKVNGL 227

 Score = 39.7 bits (91), Expect = 0.012,   Method: Composition-based stats.
 Identities = 22/94 (23%), Positives = 44/94 (46%), Gaps = 1/94 (1%)
 Frame = -1

Query: 55  LASKEGHVKMVVELLHKE-IILETTTKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQ 113
           +A   GH+  + E+LH+  + +      G T  H++    + ++   LV   A +N  + 
Sbjct: 496 IACSSGHLD-IAEMLHRRGVQINVVNINGYTPXHLSVYFNKFDITHFLVKINAEINTVNN 320

Query: 114 KGFTPLYMAAQENHLEVVKFLLENGANQNVATED 147
            G TP+Y+AA   + +++  ++  G   N    D
Sbjct: 319 AGQTPVYLAALRGNSKILALMVNAGCKVNGLVSD 218

 Score = 35.8 bits (81), Expect = 0.15,   Method: Composition-based stats.
 Identities = 20/72 (27%), Positives = 34/72 (47%)
 Frame = -1

Query: 711 VASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGASPNEVSSN 770
           +A   G++ + + L +    +N     GY+P H +      DI   L+K  A  N V++ 
Sbjct: 496 IACSSGHLDIAEMLHRRGVQINVVNINGYTPXHLSVYFNKFDITHFLVKINAEINTVNNA 317

Query: 771 GTTPLAIAKRLG 782
           G TP+ +A   G
Sbjct: 316 GQTPVYLAALRG 281

 Score = 35.8 bits (81), Expect = 0.16,   Method: Composition-based stats.
 Identities = 26/95 (27%), Positives = 42/95 (44%), Gaps = 1/95 (1%)
 Frame = -1

Query: 481 AARIGHTGMVKLLLENGASPNLATTAGHTPLHTAAREGHVDTALALLEKEASQACMTKKG 540
           A   GH  + ++L   G   N+    G+TP H +      D    L++  A    +   G
Sbjct: 493 ACSSGHLDIAEMLHRRGVQINVVNINGYTPXHLSVYFNKFDITHFLVKINAEINTVNNAG 314

Query: 541 FTPLHVAAKYGKVRLAELLLEHDAHPNAAGK-NGL 574
            TP+++AA  G  ++  L++      NA  K NGL
Sbjct: 313 QTPVYLAALRGNSKILALMV------NAGCKVNGL 227
>12417
          Length = 954

 Score = 60.1 bits (144), Expect = 8e-09,   Method: Compositional matrix adjust.
 Identities = 33/78 (42%), Positives = 47/78 (60%)
 Frame = +2

Query: 709 LHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGASPNEVS 768
           L +A++ G  K+   L+Q  ADVN+ T+ G +PLH A+ QGH  IV LLL+ GA  +   
Sbjct: 245 LAMAANRGLDKMCSQLIQTGADVNSATEHGRTPLHXASAQGHGHIVDLLLEKGADIDAED 424

Query: 769 SNGTTPLAIAKRLGYISV 786
             G T L+IA + G+ S 
Sbjct: 425 DYGDTALSIADQFGFKSC 478

 Score = 59.3 bits (142), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 34/106 (32%), Positives = 61/106 (57%), Gaps = 2/106 (1%)
 Frame = +2

Query: 80  KKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGA 139
           ++ + AL +AA  G D++  +L+  GA+VN+ ++ G TPL+ A+ + H  +V  LLE GA
Sbjct: 227 ERASVALAMAANRGLDKMCSQLIQTGADVNSATEHGRTPLHXASAQGHGHIVDLLLEKGA 406

Query: 140 NQNVATEDGFTPLAVALQQGHENV--VAHLINYGTKGKVRLPALHI 183
           + +   + G T L++A Q G ++      L ++  + K   PA +I
Sbjct: 407 DIDAEDDYGDTALSIADQFGFKSCGRXLFLFHWQQRAKKVTPARNI 544

 Score = 51.6 bits (122), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 38/137 (27%), Positives = 61/137 (44%), Gaps = 16/137 (11%)
 Frame = +2

Query: 596 GGSPHSPAWNGYTPLHIAAKQNQIEVARSL-----LQYGGSANAESV-----------QG 639
           G + H   W  +T L  A  QN ++    L      +Y  S N++ +           + 
Sbjct: 59  GATLHMRVWPMWTSLVEAVAQNDVDHVMMLGVTNPTEYR-SPNSDYMTKRARKAWLEERA 235

Query: 640 VTPLHLAAQEGHTEMVALLLSKQANGNLGNKSGLTPLHLVSQEGHVPVADVLIKHGVTVD 699
              L +AA  G  +M + L+   A+ N   + G TPLH  S +GH  + D+L++ G  +D
Sbjct: 236 SVALAMAANRGLDKMCSQLIQTGADVNSATEHGRTPLHXASAQGHGHIVDLLLEKGADID 415

Query: 700 ATTRMGYTPLHVASHYG 716
           A    G T L +A  +G
Sbjct: 416 AEDDYGDTALSIADQFG 466

 Score = 50.4 bits (119), Expect = 6e-06,   Method: Compositional matrix adjust.
 Identities = 29/74 (39%), Positives = 42/74 (56%)
 Frame = +2

Query: 346 LHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHIRVMELLLKTGASIDAVT 405
           L +AA+ G  ++   L+  GA  NS   +G TPLH A  + H  +++LLL+ GA IDA  
Sbjct: 245 LAMAANRGLDKMCSQLIQTGADVNSATEHGRTPLHXASAQGHGHIVDLLLEKGADIDAED 424

Query: 406 ESGLTPLHVASFMG 419
           + G T L +A   G
Sbjct: 425 DYGDTALSIADQFG 466

 Score = 48.5 bits (114), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 30/105 (28%), Positives = 51/105 (48%)
 Frame = +2

Query: 230 LNRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETRTKDELTPLHCAARNGHV 289
           + + A   +  +     L +A+ RG   M   L+  GA + + T+   TPLH A+  GH 
Sbjct: 194 MTKRARKAWLEERASVALAMAANRGLDKMCSQLIQTGADVNSATEHGRTPLHXASAQGHG 373

Query: 290 RISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYNAE 334
            I ++LL+ GA I A+   G + + +A Q     C R L  ++ +
Sbjct: 374 HIVDLLLEKGADIDAEDDYGDTALSIADQFGFKSCGRXLFLFHWQ 508

 Score = 48.5 bits (114), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 27/74 (36%), Positives = 43/74 (58%)
 Frame = +2

Query: 379 LHIACKKNHIRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSN 438
           L +A  +   ++   L++TGA +++ TE G TPLH AS  GH  IV  LL++GA  +  +
Sbjct: 245 LAMAANRGLDKMCSQLIQTGADVNSATEHGRTPLHXASAQGHGHIVDLLLEKGADIDAED 424

Query: 439 VKVETPLHMAARAG 452
              +T L +A + G
Sbjct: 425 DYGDTALSIADQFG 466

 Score = 45.1 bits (105), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 29/74 (39%), Positives = 36/74 (48%)
 Frame = +2

Query: 478 LHCAARIGHTGMVKLLLENGASPNLATTAGHTPLHTAAREGHVDTALALLEKEASQACMT 537
           L  AA  G   M   L++ GA  N AT  G TPLH A+ +GH      LLEK A      
Sbjct: 245 LAMAANRGLDKMCSQLIQTGADVNSATEHGRTPLHXASAQGHGHIVDLLLEKGADIDAED 424

Query: 538 KKGFTPLHVAAKYG 551
             G T L +A ++G
Sbjct: 425 DYGDTALSIADQFG 466

 Score = 44.3 bits (103), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 39/119 (32%), Positives = 55/119 (46%), Gaps = 1/119 (0%)
 Frame = +2

Query: 1   MAERPRRSGSDPAADAATSFLRAARSGNLDKALDHL-RNGVDINTCNQNGLNGLHLASKE 59
           M +R R++  +  A  A +   AA  G LDK    L + G D+N+  ++G   LH AS +
Sbjct: 194 MTKRARKAWLEERASVALAM--AANRG-LDKMCSQLIQTGADVNSATEHGRTPLHXASAQ 364

Query: 60  GHVKMVVELLHKEIILETTTKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTP 118
           GH  +V  LL K   ++     G+TAL IA   G     R L  +      Q  K  TP
Sbjct: 365 GHGHIVDLLLEKGADIDAEDDYGDTALSIADQFGFKSCGRXLFLFHWQ---QRAKKVTP 532

 Score = 42.7 bits (99), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 32/111 (28%), Positives = 51/111 (45%)
 Frame = +2

Query: 527 LEKEASQACMTKKGFTPLHVAAKYGKVRLAELLLEHDAHPNAAGKNGLTPLHVAVHHNNL 586
           + K A +A + ++    L +AA  G  ++   L++  A  N+A ++G TPLH A    + 
Sbjct: 194 MTKRARKAWLEERASVALAMAANRGLDKMCSQLIQTGADVNSATEHGRTPLHXASAQGHG 373

Query: 587 DIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQIEVARSLLQYGGSANAESV 637
            IV LLL +G    +    G T L IA +       R L  +     A+ V
Sbjct: 374 HIVDLLLEKGADIDAEDDYGDTALSIADQFGFKSCGRXLFLFHWQQRAKKV 526

 Score = 40.8 bits (94), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 31/96 (32%), Positives = 46/96 (47%), Gaps = 9/96 (9%)
 Frame = +2

Query: 201 PNPDVLSKTG---------FTPLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIAS 251
           PN D ++K              L +AA+     +   L+  GA VN   ++G TPLH AS
Sbjct: 179 PNSDYMTKRARKAWLEERASVALAMAANRGLDKMCSQLIQTGADVNSATEHGRTPLHXAS 358

Query: 252 RRGNVIMVRLLLDRGAQIETRTKDELTPLHCAARNG 287
            +G+  +V LLL++GA I+       T L  A + G
Sbjct: 359 AQGHGHIVDLLLEKGADIDAEDDYGDTALSIADQFG 466

 Score = 37.4 bits (85), Expect = 0.054,   Method: Compositional matrix adjust.
 Identities = 29/98 (29%), Positives = 44/98 (44%)
 Frame = +2

Query: 265 RGAQIETRTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDC 324
           R A +E R       L  AA  G  ++   L+  GA + + T++G +P+H A+   H   
Sbjct: 209 RKAWLEERAS---VALAMAANRGLDKMCSQLIQTGADVNSATEHGRTPLHXASAQGHGHI 379

Query: 325 VRLLLQYNAEIDDITLDHLTPLHVAAHCGHHRVAKVLL 362
           V LLL+  A+ID       T L +A   G     + L 
Sbjct: 380 VDLLLEKGADIDAEDDYGDTALSIADQFGFKSCGRXLF 493

 Score = 36.6 bits (83), Expect = 0.10,   Method: Compositional matrix adjust.
 Identities = 23/75 (30%), Positives = 39/75 (52%)
 Frame = +2

Query: 180 ALHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFT 239
           AL +AA     +  + L+Q   + +  ++ G TPLH A+   + ++  LLL +GA ++  
Sbjct: 242 ALAMAANRGLDKMCSQLIQTGADVNSATEHGRTPLHXASAQGHGHIVDLLLEKGADIDAE 421

Query: 240 PQNGITPLHIASRRG 254
              G T L IA + G
Sbjct: 422 DDYGDTALSIADQFG 466

 Score = 36.6 bits (83), Expect = 0.11,   Method: Compositional matrix adjust.
 Identities = 21/55 (38%), Positives = 31/55 (56%)
 Frame = +2

Query: 328 LLQYNAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIA 382
           L+Q  A+++  T    TPLH A+  GH  +  +LL+KGA  ++    G T L IA
Sbjct: 290 LIQTGADVNSATEHGRTPLHXASAQGHGHIVDLLLEKGADIDAEDDYGDTALSIA 454

 Score = 34.3 bits (77), Expect = 0.46,   Method: Compositional matrix adjust.
 Identities = 21/59 (35%), Positives = 29/59 (49%)
 Frame = +2

Query: 592 LLPRGGSPHSPAWNGYTPLHIAAKQNQIEVARSLLQYGGSANAESVQGVTPLHLAAQEG 650
           L+  G   +S   +G TPLH A+ Q    +   LL+ G   +AE   G T L +A Q G
Sbjct: 290 LIQTGADVNSATEHGRTPLHXASAQGHGHIVDLLLEKGADIDAEDDYGDTALSIADQFG 466

 Score = 33.1 bits (74), Expect = 1.0,   Method: Compositional matrix adjust.
 Identities = 19/43 (44%), Positives = 23/43 (53%)
 Frame = +2

Query: 476 TPLHCAARIGHTGMVKLLLENGASPNLATTAGHTPLHTAAREG 518
           TPLH A+  GH  +V LLLE GA  +     G T L  A + G
Sbjct: 338 TPLHXASAQGHGHIVDLLLEKGADIDAEDDYGDTALSIADQFG 466

 Score = 32.7 bits (73), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 24/70 (34%), Positives = 32/70 (45%)
 Frame = +2

Query: 511 LHTAAREGHVDTALALLEKEASQACMTKKGFTPLHVAAKYGKVRLAELLLEHDAHPNAAG 570
           L  AA  G       L++  A     T+ G TPLH A+  G   + +LLLE  A  +A  
Sbjct: 245 LAMAANRGLDKMCSQLIQTGADVNSATEHGRTPLHXASAQGHGHIVDLLLEKGADIDAED 424

Query: 571 KNGLTPLHVA 580
             G T L +A
Sbjct: 425 DYGDTALSIA 454
>20036
          Length = 1849

 Score = 59.3 bits (142), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 44/133 (33%), Positives = 60/133 (45%), Gaps = 7/133 (5%)
 Frame = +3

Query: 567 NAAGKNGLTPLHVAVHHNNLDIVKLLL-PRGGSPHSPAWNGYTPLHIAA-----KQNQIE 620
           N    NG + +H  V H N DIV LLL         P   GYTP  +A+       +  +
Sbjct: 867 NLVDSNGNSAIHYCVSHCNFDIVGLLLDTEVCDVKRPNKAGYTPTMLASLAFIQNDDHRD 1046

Query: 621 VARSLLQYGGSANAESVQ-GVTPLHLAAQEGHTEMVALLLSKQANGNLGNKSGLTPLHLV 679
           + R L    G  NA + Q G T L LA  +  T+MV LLL   A+ N  +  G T L   
Sbjct: 1047IIRQLF-LAGDINACAEQTGQTALMLATSQCRTDMVELLLETGADCNQQDFDGSTALMCA 1223

Query: 680 SQEGHVPVADVLI 692
            + GH  +  +L+
Sbjct: 1224CEHGHTAIVQLLL 1262

 Score = 59.3 bits (142), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 42/164 (25%), Positives = 69/164 (42%), Gaps = 7/164 (4%)
 Frame = +3

Query: 538  KKGFTPLHVAAKYGKVRLAELLLEHDA----HPNAAGKN--GLTPLHVAVHHNNLDIVKL 591
              G + +H    +    +  LLL+ +      PN AG     L  L    + ++ DI++ 
Sbjct: 879  SNGNSAIHYCVSHCNFDIVGLLLDTEVCDVKRPNKAGYTPTMLASLAFIQNDDHRDIIRQ 1058

Query: 592  LLPRGGSPHSPAWNGYTPLHIAAKQNQIEVARSLLQYGGSANAESVQGVTPLHLAAQEGH 651
            L   G         G T L +A  Q + ++   LL+ G   N +   G T L  A + GH
Sbjct: 1059 LFLAGDINACAEQTGQTALMLATSQCRTDMVELLLETGADCNQQDFDGSTALMCACEHGH 1238

Query: 652  TEMVALLLSK-QANGNLGNKSGLTPLHLVSQEGHVPVADVLIKH 694
            T +V LLL++   +  L +    T L +  +  H  +  +L KH
Sbjct: 1239 TAIVQLLLAQPHCDATLTDNENSTALSIAMEASHKDIGVILYKH 1370

 Score = 52.0 bits (123), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 46/166 (27%), Positives = 73/166 (43%), Gaps = 7/166 (4%)
 Frame = +3

Query: 620 EVARSLLQYGGSANAESVQGVTPLHLAAQEGHTEMVALLLSKQ-ANGNLGNKSGLTP--- 675
           E++  LL+Y    N     G + +H      + ++V LLL  +  +    NK+G TP   
Sbjct: 834 EISHRLLEY--IVNLVDSNGNSAIHYCVSHCNFDIVGLLLDTEVCDVKRPNKAGYTPTML 1007

Query: 676 --LHLVSQEGHVPVADVLIKHGVTVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNA 733
             L  +  + H  +   L   G       + G T L +A+      +V+ LL+  AD N 
Sbjct: 1008ASLAFIQNDDHRDIIRQLFLAGDINACAEQTGQTALMLATSQCRTDMVELLLETGADCNQ 1187

Query: 734 KTKLGYSPLHQAAQQGHTDIVTLLLKNGASPNEVSSN-GTTPLAIA 778
           +   G + L  A + GHT IV LLL        ++ N  +T L+IA
Sbjct: 1188QDFDGSTALMCACEHGHTAIVQLLLAQPHCDATLTDNENSTALSIA 1325

 Score = 51.2 bits (121), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 40/134 (29%), Positives = 67/134 (50%), Gaps = 7/134 (5%)
 Frame = +3

Query: 42  INTCNQNGLNGLHLASKEGHVKMVVELLHKEII-LETTTKKGNTALHIAALA-----GQD 95
           +N  + NG + +H      +  +V  LL  E+  ++   K G T   +A+LA        
Sbjct: 864 VNLVDSNGNSAIHYCVSHCNFDIVGLLLDTEVCDVKRPNKAGYTPTMLASLAFIQNDDHR 1043

Query: 96  EVVRELVNYGANVNAQS-QKGFTPLYMAAQENHLEVVKFLLENGANQNVATEDGFTPLAV 154
           +++R+L   G ++NA + Q G T L +A  +   ++V+ LLE GA+ N    DG T L  
Sbjct: 1044DIIRQLFLAG-DINACAEQTGQTALMLATSQCRTDMVELLLETGADCNQQDFDGSTALMC 1220

Query: 155 ALQQGHENVVAHLI 168
           A + GH  +V  L+
Sbjct: 1221ACEHGHTAIVQLLL 1262

 Score = 44.7 bits (104), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 34/103 (33%), Positives = 45/103 (43%), Gaps = 5/103 (4%)
 Frame = +3

Query: 506  AGHTPLHTAA-----REGHVDTALALLEKEASQACMTKKGFTPLHVAAKYGKVRLAELLL 560
            AG+TP   A+      + H D    L       AC  + G T L +A    +  + ELLL
Sbjct: 984  AGYTPTMLASLAFIQNDDHRDIIRQLFLAGDINACAEQTGQTALMLATSQCRTDMVELLL 1163

Query: 561  EHDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPA 603
            E  A  N    +G T L  A  H +  IV+LLL +   PH  A
Sbjct: 1164 ETGADCNQQDFDGSTALMCACEHGHTAIVQLLLAQ---PHCDA 1283

 Score = 44.3 bits (103), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 33/97 (34%), Positives = 48/97 (49%), Gaps = 7/97 (7%)
 Frame = +3

Query: 207  SKTGFTPLHIA--AHYENLN----VAQLLLNRGASVN-FTPQNGITPLHIASRRGNVIMV 259
            +K G+TP  +A  A  +N +    + QL L     +N    Q G T L +A+ +    MV
Sbjct: 978  NKAGYTPTMLASLAFIQNDDHRDIIRQLFL--AGDINACAEQTGQTALMLATSQCRTDMV 1151

Query: 260  RLLLDRGAQIETRTKDELTPLHCAARNGHVRISEILL 296
             LLL+ GA    +  D  T L CA  +GH  I ++LL
Sbjct: 1152 ELLLETGADCNQQDFDGSTALMCACEHGHTAIVQLLL 1262

 Score = 44.3 bits (103), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 45/159 (28%), Positives = 66/159 (41%), Gaps = 9/159 (5%)
 Frame = +3

Query: 307  KNGLSPIHMAAQGDHLDCVRLLLQYNAEIDDI--------TLDHLTPLHVAAHCGHHRVA 358
             NG S IH      + D V LLL  + E+ D+        T   L  L    +  H  + 
Sbjct: 879  SNGNSAIHYCVSHCNFDIVGLLL--DTEVCDVKRPNKAGYTPTMLASLAFIQNDDHRDII 1052

Query: 359  KVLLDKGAKPNSRALNGFTPLHIACKKNHIRVMELLLKTGASIDAVTESGLTPLHVASFM 418
            + L   G         G T L +A  +    ++ELLL+TGA  +     G T L  A   
Sbjct: 1053 RQLFLAGDINACAEQTGQTALMLATSQCRTDMVELLLETGADCNQQDFDGSTALMCACEH 1232

Query: 419  GHLPIVKNLL-QRGASPNVSNVKVETPLHMAARAGHTEV 456
            GH  IV+ LL Q      +++ +  T L +A  A H ++
Sbjct: 1233 GHTAIVQLLLAQPHCDATLTDNENSTALSIAMEASHKDI 1349

 Score = 36.2 bits (82), Expect = 0.14,   Method: Compositional matrix adjust.
 Identities = 28/88 (31%), Positives = 37/88 (42%), Gaps = 1/88 (1%)
 Frame = +3

Query: 476  TPLHCAARIGHTGMVKLLLENGASPNLATTAGHTPLHTAAREGHVDTALALLEKEASQAC 535
            T L  A     T MV+LLLE GA  N     G T L  A   GH      LL +    A 
Sbjct: 1107 TALMLATSQCRTDMVELLLETGADCNQQDFDGSTALMCACEHGHTAIVQLLLAQPHCDAT 1286

Query: 536  MT-KKGFTPLHVAAKYGKVRLAELLLEH 562
            +T  +  T L +A +     +  +L +H
Sbjct: 1287 LTDNENSTALSIAMEASHKDIGVILYKH 1370
>11861
          Length = 586

 Score = 58.9 bits (141), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 45/157 (28%), Positives = 76/157 (48%), Gaps = 4/157 (2%)
 Frame = -1

Query: 610 LHIAAKQNQIEVARSLLQYGGSANAESVQGVTPL-HLAAQEGHTEMVAL--LLSKQANGN 666
           LH AAK++Q ++    L +G   N    QG TPL  +A ++ H + VA+  LL + A+ +
Sbjct: 475 LHEAAKRHQWDIVDHCLTHGADINKVDEQGFTPLFRVAYKDVHPDWVAVKELLIRGADAS 296

Query: 667 LGNKSGLTPLHLVSQEGHVPVADVLIKHGVTVDATTRMGYTPLHVASHYGNIKLVKFLLQ 726
               S    + L  ++    V   LI +   +    +MG TPL       N++++ F +Q
Sbjct: 295 ATESSRKPLVKLAVRKKQWDVVKALILNHADIYRPDKMGQTPLSTLITAANMEMIHFAIQ 116

Query: 727 HQADVNAKTKL-GYSPLHQAAQQGHTDIVTLLLKNGA 762
           H   +     + G + LH A Q    D++  L+K+GA
Sbjct: 115 HCPGMAGAVDMSGQTILHVACQLQRPDLLQXLIKDGA 5

 Score = 48.9 bits (115), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 50/162 (30%), Positives = 80/162 (49%), Gaps = 12/162 (7%)
 Frame = -1

Query: 85  ALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQEN---HLEVVKFLLENGANQ 141
           ALH AA   Q ++V   + +GA++N   ++GFTPL+  A ++       VK LL  GA+ 
Sbjct: 478 ALHEAAKRHQWDIVDHCLTHGADINKVDEQGFTPLFRVAYKDVHPDWVAVKELLIRGADA 299

Query: 142 NVATEDGFTPLA-VALQQGHENVVAHLI-NYG------TKGKVRLPALHIAARNDDTRTA 193
           + ATE    PL  +A+++   +VV  LI N+         G+  L  L  AA  +    A
Sbjct: 298 S-ATESSRKPLVKLAVRKKQWDVVKALILNHADIYRPDKMGQTPLSTLITAANMEMIHFA 122

Query: 194 AVLLQNDPN-PDVLSKTGFTPLHIAAHYENLNVAQLLLNRGA 234
              +Q+ P     +  +G T LH+A   +  ++ Q L+  GA
Sbjct: 121 ---IQHCPGMAGAVDMSGQTILHVACQLQRPDLLQXLIKDGA 5

 Score = 41.6 bits (96), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 42/157 (26%), Positives = 65/157 (41%), Gaps = 5/157 (3%)
 Frame = -1

Query: 544 LHVAAKYGKVRLAELLLEHDAHPNAAGKNGLTPLHVAVH---HNNLDIVKLLLPRGGSPH 600
           LH AAK  +  + +  L H A  N   + G TPL    +   H +   VK LL RG    
Sbjct: 475 LHEAAKRHQWDIVDHCLTHGADINKVDEQGFTPLFRVAYKDVHPDWVAVKELLIRGADAS 296

Query: 601 SPAWNGYTPLHIAAKQNQIEVARSLLQYGGSANAESVQGVTPLHLAAQEGHTEMVALLLS 660
           +   +    + +A ++ Q +V ++L+            G TPL       + EM+   + 
Sbjct: 295 ATESSRKPLVKLAVRKKQWDVVKALILNHADIYRPDKMGQTPLSTLITAANMEMIHFAI- 119

Query: 661 KQANGNLG--NKSGLTPLHLVSQEGHVPVADVLIKHG 695
           +   G  G  + SG T LH+  Q     +   LIK G
Sbjct: 118 QHCPGMAGAVDMSGQTILHVACQLQRPDLLQXLIKDG 8

 Score = 38.9 bits (89), Expect = 0.019,   Method: Compositional matrix adjust.
 Identities = 31/115 (26%), Positives = 53/115 (46%), Gaps = 4/115 (3%)
 Frame = -1

Query: 666 NLGNKSGLTPLHLVSQEGHVPVADVLIKHGVTVDATTRMGYTPLHVASH---YGNIKLVK 722
           ++GN+     LH  ++     + D  + HG  ++     G+TPL   ++   + +   VK
Sbjct: 505 SMGNQHRCIALHEAAKRHQWDIVDHCLTHGADINKVDEQGFTPLFRVAYKDVHPDWVAVK 326

Query: 723 FLLQHQADVNAKTKLGYSPLHQ-AAQQGHTDIVTLLLKNGASPNEVSSNGTTPLA 776
            LL   AD +A T+    PL + A ++   D+V  L+ N A        G TPL+
Sbjct: 325 ELLIRGADASA-TESSRKPLVKLAVRKKQWDVVKALILNHADIYRPDKMGQTPLS 164

 Score = 35.8 bits (81), Expect = 0.15,   Method: Compositional matrix adjust.
 Identities = 39/189 (20%), Positives = 69/189 (36%), Gaps = 3/189 (1%)
 Frame = -1

Query: 214 LHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIASRRG---NVIMVRLLLDRGAQIE 270
           LH AA     ++    L  GA +N   + G TPL   + +    + + V+ LL RGA   
Sbjct: 475 LHEAAKRHQWDIVDHCLTHGADINKVDEQGFTPLFRVAYKDVHPDWVAVKELLIRGADAS 296

Query: 271 TRTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQ 330
                    +  A R     + + L+ + A I    K G +P+       +++ +   +Q
Sbjct: 295 ATESSRKPLVKLAVRKKQWDVVKALILNHADIYRPDKMGQTPLSTLITAANMEMIHFAIQ 116

Query: 331 YNAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHIRV 390
                               HC                 +  ++G T LH+AC+     +
Sbjct: 115 --------------------HCP------------GMAGAVDMSGQTILHVACQLQRPDL 32

Query: 391 MELLLKTGA 399
           ++ L+K GA
Sbjct: 31  LQXLIKDGA 5

 Score = 32.0 bits (71), Expect = 2.1,   Method: Compositional matrix adjust.
 Identities = 40/163 (24%), Positives = 72/163 (44%), Gaps = 5/163 (3%)
 Frame = -1

Query: 177 RLPALHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAA----HYENLNVAQLLLNR 232
           R  ALH AA+          L +  + + + + GFTPL   A    H + + V +LL+ R
Sbjct: 487 RCIALHEAAKRHQWDIVDHCLTHGADINKVDEQGFTPLFRVAYKDVHPDWVAVKELLI-R 311

Query: 233 GASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETRTKDELTPLHCAARNGHVRIS 292
           GA  + T  +    + +A R+    +V+ L+   A I    K   TPL       ++ + 
Sbjct: 310 GADASATESSRKPLVKLAVRKKQWDVVKALILNHADIYRPDKMGQTPLSTLITAANMEMI 131

Query: 293 EILLDHGAPIQ-AKTKNGLSPIHMAAQGDHLDCVRLLLQYNAE 334
              + H   +  A   +G + +H+A Q    D ++ L++  A+
Sbjct: 130 HFAIQHCPGMAGAVDMSGQTILHVACQLQRPDLLQXLIKDGAD 2
>09180
          Length = 610

 Score = 55.8 bits (133), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 27/83 (32%), Positives = 47/83 (56%)
 Frame = +3

Query: 658 LLSKQANGNLGNKSGLTPLHLVSQEGHVPVADVLIKHGVTVDATTRMGYTPLHVASHYGN 717
           L +K    N   K+G T LH+ + +G++ V +VL++ GV ++A    G+T LH A H+G 
Sbjct: 123 LQNKNIEDNAHPKTGATALHVSAAKGYINVMNVLLQAGVDINAQDADGWTSLHAAVHWGQ 302

Query: 718 IKLVKFLLQHQADVNAKTKLGYS 740
               + L+ H  D++ K   G++
Sbjct: 303 EDSCQVLVDHFCDMDVKNNAGHT 371

 Score = 44.3 bits (103), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 25/77 (32%), Positives = 37/77 (48%)
 Frame = +3

Query: 606 GYTPLHIAAKQNQIEVARSLLQYGGSANAESVQGVTPLHLAAQEGHTEMVALLLSKQANG 665
           G T LH++A +  I V   LLQ G   NA+   G T LH A   G  +   +L+    + 
Sbjct: 165 GATALHVSAAKGYINVMNVLLQAGVDINAQDADGWTSLHAAVHWGQEDSCQVLVDHFCDM 344

Query: 666 NLGNKSGLTPLHLVSQE 682
           ++ N +G T   L  +E
Sbjct: 345 DVKNNAGHTVFDLADKE 395

 Score = 43.1 bits (100), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 23/78 (29%), Positives = 40/78 (51%)
 Frame = +3

Query: 703 RMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGA 762
           + G T LHV++  G I ++  LLQ   D+NA+   G++ LH A   G  D   +L+ +  
Sbjct: 159 KTGATALHVSAAKGYINVMNVLLQAGVDINAQDADGWTSLHAAVHWGQEDSCQVLVDHFC 338

Query: 763 SPNEVSSNGTTPLAIAKR 780
             +  ++ G T   +A +
Sbjct: 339 DMDVKNNAGHTVFDLADK 392

 Score = 41.6 bits (96), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 23/76 (30%), Positives = 39/76 (51%)
 Frame = +3

Query: 80  KKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGA 139
           K G TALH++A  G   V+  L+  G ++NAQ   G+T L+ A      +  + L+++  
Sbjct: 159 KTGATALHVSAAKGYINVMNVLLQAGVDINAQDADGWTSLHAAVHWGQEDSCQVLVDHFC 338

Query: 140 NQNVATEDGFTPLAVA 155
           + +V    G T   +A
Sbjct: 339 DMDVKNNAGHTVFDLA 386

 Score = 41.2 bits (95), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 29/112 (25%), Positives = 50/112 (44%)
 Frame = +3

Query: 208 KTGFTPLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGA 267
           KTG T LH++A    +NV  +LL  G  +N    +G T LH A   G     ++L+D   
Sbjct: 159 KTGATALHVSAAKGYINVMNVLLQAGVDINAQDADGWTSLHAAVHWGQEDSCQVLVDHFC 338

Query: 268 QIETRTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQG 319
            ++ +     T    A +   +++ E L    A ++  +++    IH    G
Sbjct: 339 DMDVKNNAGHTVFDLADKE-MLKVLEELKKKQAKLRTASESNSDIIHTPGHG 491

 Score = 40.8 bits (94), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 25/79 (31%), Positives = 37/79 (46%)
 Frame = +3

Query: 538 KKGFTPLHVAAKYGKVRLAELLLEHDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGG 597
           K G T LHV+A  G + +  +LL+     NA   +G T LH AVH    D  ++L+    
Sbjct: 159 KTGATALHVSAAKGYINVMNVLLQAGVDINAQDADGWTSLHAAVHWGQEDSCQVLVDHFC 338

Query: 598 SPHSPAWNGYTPLHIAAKQ 616
                   G+T   +A K+
Sbjct: 339 DMDVKNNAGHTVFDLADKE 395

 Score = 38.9 bits (89), Expect = 0.021,   Method: Compositional matrix adjust.
 Identities = 25/90 (27%), Positives = 45/90 (50%)
 Frame = +3

Query: 560 LEHDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQI 619
           +E +AHP    K G T LHV+     ++++ +LL  G   ++   +G+T LH A    Q 
Sbjct: 138 IEDNAHP----KTGATALHVSAAKGYINVMNVLLQAGVDINAQDADGWTSLHAAVHWGQE 305

Query: 620 EVARSLLQYGGSANAESVQGVTPLHLAAQE 649
           +  + L+ +    + ++  G T   LA +E
Sbjct: 306 DSCQVLVDHFCDMDVKNNAGHTVFDLADKE 395

 Score = 37.7 bits (86), Expect = 0.047,   Method: Compositional matrix adjust.
 Identities = 25/100 (25%), Positives = 54/100 (54%)
 Frame = +3

Query: 47  QNGLNGLHLASKEGHVKMVVELLHKEIILETTTKKGNTALHIAALAGQDEVVRELVNYGA 106
           + G   LH+++ +G++ ++  LL   + +      G T+LH A   GQ++  + LV++  
Sbjct: 159 KTGATALHVSAAKGYINVMNVLLQAGVDINAQDADGWTSLHAAVHWGQEDSCQVLVDHFC 338

Query: 107 NVNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQNVATE 146
           +++ ++  G T   +A +E  L+V++ L +  A    A+E
Sbjct: 339 DMDVKNNAGHTVFDLADKE-MLKVLEELKKKQAKLRTASE 455

 Score = 37.4 bits (85), Expect = 0.052,   Method: Compositional matrix adjust.
 Identities = 32/112 (28%), Positives = 53/112 (47%), Gaps = 5/112 (4%)
 Frame = +3

Query: 344 TPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHIRVMELLLKTGASIDA 403
           T LHV+A  G+  V  VLL  G   N++  +G+T LH A         ++L+     +D 
Sbjct: 171 TALHVSAAKGYINVMNVLLQAGVDINAQDADGWTSLHAAVHWGQEDSCQVLVDHFCDMDV 350

Query: 404 VTESGLTPLHVASFMGHLPIVKNLLQ-----RGASPNVSNVKVETPLHMAAR 450
              +G T   +A     L +++ L +     R AS + S++ + TP H + R
Sbjct: 351 KNNAGHTVFDLAD-KEMLKVLEELKKKQAKLRTASESNSDI-IHTPGHGSKR 500

 Score = 34.3 bits (77), Expect = 0.47,   Method: Compositional matrix adjust.
 Identities = 31/122 (25%), Positives = 52/122 (42%), Gaps = 7/122 (5%)
 Frame = +3

Query: 175 KVRLPALHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGA 234
           K    ALH++A         VLLQ   + +     G+T LH A H+   +  Q+L++   
Sbjct: 159 KTGATALHVSAAKGYINVMNVLLQAGVDINAQDADGWTSLHAAVHWGQEDSCQVLVDHFC 338

Query: 235 SVNFTPQNGITPLHIASRRGNVIMVRLLLD-RGAQIETRTKDEL------TPLHCAARNG 287
            ++     G T   +A +     M+++L + +  Q + RT  E       TP H + R  
Sbjct: 339 DMDVKNNAGHTVFDLADKE----MLKVLEELKKKQAKLRTASESNSDIIHTPGHGSKRRS 506

Query: 288 HV 289
            V
Sbjct: 507 SV 512

 Score = 33.5 bits (75), Expect = 0.89,   Method: Compositional matrix adjust.
 Identities = 16/47 (34%), Positives = 25/47 (53%)
 Frame = +3

Query: 406 ESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAG 452
           ++G T LHV++  G++ ++  LLQ G   N  +    T LH A   G
Sbjct: 159 KTGATALHVSAAKGYINVMNVLLQAGVDINAQDADGWTSLHAAVHWG 299
>28113
          Length = 449

 Score = 55.5 bits (132), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 32/100 (32%), Positives = 52/100 (52%)
 Frame = -3

Query: 594 PRGGSPHSPAWNGYTPLHIAAKQNQIEVARSLLQYGGSANAESVQGVTPLHLAAQEGHTE 653
           PR  +P  P W    PLH +A Q  +   +SLL +G   + +       +H A+  G  +
Sbjct: 363 PR--NPVEPRWRDKYPLHASAAQGDVHHVQSLLNHGHHHSKKDSIAWAAIHYASWYGSAD 190

Query: 654 MVALLLSKQANGNLGNKSGLTPLHLVSQEGHVPVADVLIK 693
           +V +LL    + NL N   LTPLH+ +++G   VA+ L++
Sbjct: 189 VVEILLDAGCSPNLTNSELLTPLHIAAKKGFPDVAEHLVQ 70

 Score = 55.1 bits (131), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 29/83 (34%), Positives = 46/83 (55%)
 Frame = -3

Query: 708 PLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGASPNEV 767
           PLH ++  G++  V+ LL H    + K  + ++ +H A+  G  D+V +LL  G SPN  
Sbjct: 324 PLHASAAQGDVHHVQSLLNHGHHHSKKDSIAWAAIHYASWYGSADVVEILLDAGCSPNLT 145

Query: 768 SSNGTTPLAIAKRLGYISVTDVL 790
           +S   TPL IA + G+  V + L
Sbjct: 144 NSELLTPLHIAAKKGFPDVAEHL 76

 Score = 49.3 bits (116), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 26/79 (32%), Positives = 42/79 (53%)
 Frame = -3

Query: 378 PLHIACKKNHIRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVS 437
           PLH +  +  +  ++ LL  G             +H AS+ G   +V+ LL  G SPN++
Sbjct: 324 PLHASAAQGDVHHVQSLLNHGHHHSKKDSIAWAAIHYASWYGSADVVEILLDAGCSPNLT 145

Query: 438 NVKVETPLHMAARAGHTEV 456
           N ++ TPLH+AA+ G  +V
Sbjct: 144 NSELLTPLHIAAKKGFPDV 88

 Score = 48.9 bits (115), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 31/85 (36%), Positives = 44/85 (51%)
 Frame = -3

Query: 543 PLHVAAKYGKVRLAELLLEHDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSP 602
           PLH +A  G V   + LL H  H +         +H A  + + D+V++LL  G SP+  
Sbjct: 324 PLHASAAQGDVHHVQSLLNHGHHHSKKDSIAWAAIHYASWYGSADVVEILLDAGCSPNLT 145

Query: 603 AWNGYTPLHIAAKQNQIEVARSLLQ 627
                TPLHIAAK+   +VA  L+Q
Sbjct: 144 NSELLTPLHIAAKKGFPDVAEHLVQ 70

 Score = 45.4 bits (106), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 23/83 (27%), Positives = 45/83 (54%)
 Frame = -3

Query: 86  LHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQNVAT 145
           LH +A  G    V+ L+N+G + + +    +  ++ A+     +VV+ LL+ G + N+  
Sbjct: 321 LHASAAQGDVHHVQSLLNHGHHHSKKDSIAWAAIHYASWYGSADVVEILLDAGCSPNLTN 142

Query: 146 EDGFTPLAVALQQGHENVVAHLI 168
            +  TPL +A ++G  +V  HL+
Sbjct: 141 SELLTPLHIAAKKGFPDVAEHLV 73

 Score = 44.3 bits (103), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 28/90 (31%), Positives = 41/90 (45%)
 Frame = -3

Query: 442 ETPLHMAARAGHTEVXXXXXXXXXXXXXXXXXXXTPLHCAARIGHTGMVKLLLENGASPN 501
           + PLH +A  G                         +H A+  G   +V++LL+ G SPN
Sbjct: 330 KYPLHASAAQGDVHHVQSLLNHGHHHSKKDSIAWAAIHYASWYGSADVVEILLDAGCSPN 151

Query: 502 LATTAGHTPLHTAAREGHVDTALALLEKEA 531
           L  +   TPLH AA++G  D A  L++ EA
Sbjct: 150 LTNSELLTPLHIAAKKGFPDVAEHLVQAEA 61

 Score = 43.9 bits (102), Expect = 6e-04,   Method: Compositional matrix adjust.
 Identities = 23/74 (31%), Positives = 38/74 (51%)
 Frame = -3

Query: 181 LHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFTP 240
           LH +A   D      LL +  +        +  +H A+ Y + +V ++LL+ G S N T 
Sbjct: 321 LHASAAQGDVHHVQSLLNHGHHHSKKDSIAWAAIHYASWYGSADVVEILLDAGCSPNLTN 142

Query: 241 QNGITPLHIASRRG 254
              +TPLHIA+++G
Sbjct: 141 SELLTPLHIAAKKG 100

 Score = 43.9 bits (102), Expect = 6e-04,   Method: Compositional matrix adjust.
 Identities = 30/95 (31%), Positives = 46/95 (48%)
 Frame = -3

Query: 246 PLHIASRRGNVIMVRLLLDRGAQIETRTKDELTPLHCAARNGHVRISEILLDHGAPIQAK 305
           PLH ++ +G+V  V+ LL+ G     +       +H A+  G   + EILLD G      
Sbjct: 324 PLHASAAQGDVHHVQSLLNHGHHHSKKDSIAWAAIHYASWYGSADVVEILLDAGCSPNLT 145

Query: 306 TKNGLSPIHMAAQGDHLDCVRLLLQYNAEIDDITL 340
               L+P+H+AA+    D    L+Q  AE  D+ L
Sbjct: 144 NSELLTPLHIAAKKGFPDVAEHLVQ--AEAIDLNL 46

 Score = 42.4 bits (98), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 25/84 (29%), Positives = 39/84 (46%)
 Frame = -3

Query: 510 PLHTAAREGHVDTALALLEKEASQACMTKKGFTPLHVAAKYGKVRLAELLLEHDAHPNAA 569
           PLH +A +G V    +LL      +      +  +H A+ YG   + E+LL+    PN  
Sbjct: 324 PLHASAAQGDVHHVQSLLNHGHHHSKKDSIAWAAIHYASWYGSADVVEILLDAGCSPNLT 145

Query: 570 GKNGLTPLHVAVHHNNLDIVKLLL 593
               LTPLH+A      D+ + L+
Sbjct: 144 NSELLTPLHIAAKKGFPDVAEHLV 73

 Score = 42.0 bits (97), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 32/94 (34%), Positives = 46/94 (48%)
 Frame = -3

Query: 269 IETRTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLL 328
           +E R +D+  PLH +A  G V   + LL+HG     K     + IH A+     D V +L
Sbjct: 351 VEPRWRDKY-PLHASAAQGDVHHVQSLLNHGHHHSKKDSIAWAAIHYASWYGSADVVEIL 175

Query: 329 LQYNAEIDDITLDHLTPLHVAAHCGHHRVAKVLL 362
           L      +    + LTPLH+AA  G   VA+ L+
Sbjct: 174 LDAGCSPNLTNSELLTPLHIAAKKGFPDVAEHLV 73

 Score = 41.6 bits (96), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 25/85 (29%), Positives = 40/85 (47%)
 Frame = -3

Query: 675 PLHLVSQEGHVPVADVLIKHGVTVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAK 734
           PLH  + +G V     L+ HG        + +  +H AS YG+  +V+ LL      N  
Sbjct: 324 PLHASAAQGDVHHVQSLLNHGHHHSKKDSIAWAAIHYASWYGSADVVEILLDAGCSPNLT 145

Query: 735 TKLGYSPLHQAAQQGHTDIVTLLLK 759
                +PLH AA++G  D+   L++
Sbjct: 144 NSELLTPLHIAAKKGFPDVAEHLVQ 70

 Score = 41.2 bits (95), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 28/98 (28%), Positives = 48/98 (48%), Gaps = 1/98 (1%)
 Frame = -3

Query: 642 PLHLAAQEGHTEMVALLLSKQANGNLGNKSGLTPLHLVSQEGHVPVADVLIKHGVTVDAT 701
           PLH +A +G    V  LL+   + +  +      +H  S  G   V ++L+  G + + T
Sbjct: 324 PLHASAAQGDVHHVQSLLNHGHHHSKKDSIAWAAIHYASWYGSADVVEILLDAGCSPNLT 145

Query: 702 TRMGYTPLHVASHYGNIKLVKFLLQHQA-DVNAKTKLG 738
                TPLH+A+  G   + + L+Q +A D+N + K G
Sbjct: 144 NSELLTPLHIAAKKGFPDVAEHLVQAEAIDLNLRDKDG 31

 Score = 40.4 bits (93), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 28/88 (31%), Positives = 42/88 (47%)
 Frame = -3

Query: 477 PLHCAARIGHTGMVKLLLENGASPNLATTAGHTPLHTAAREGHVDTALALLEKEASQACM 536
           PLH +A  G    V+ LL +G   +   +     +H A+  G  D    LL+   S    
Sbjct: 324 PLHASAAQGDVHHVQSLLNHGHHHSKKDSIAWAAIHYASWYGSADVVEILLDAGCSPNLT 145

Query: 537 TKKGFTPLHVAAKYGKVRLAELLLEHDA 564
             +  TPLH+AAK G   +AE L++ +A
Sbjct: 144 NSELLTPLHIAAKKGFPDVAEHLVQAEA 61

 Score = 38.5 bits (88), Expect = 0.026,   Method: Compositional matrix adjust.
 Identities = 26/88 (29%), Positives = 42/88 (47%)
 Frame = -3

Query: 345 PLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHIRVMELLLKTGASIDAV 404
           PLH +A  G     + LL+ G   + +    +  +H A       V+E+LL  G S +  
Sbjct: 324 PLHASAAQGDVHHVQSLLNHGHHHSKKDSIAWAAIHYASWYGSADVVEILLDAGCSPNLT 145

Query: 405 TESGLTPLHVASFMGHLPIVKNLLQRGA 432
               LTPLH+A+  G   + ++L+Q  A
Sbjct: 144 NSELLTPLHIAAKKGFPDVAEHLVQAEA 61

 Score = 38.1 bits (87), Expect = 0.033,   Method: Compositional matrix adjust.
 Identities = 28/98 (28%), Positives = 48/98 (48%), Gaps = 1/98 (1%)
 Frame = -3

Query: 576 PLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQIEVARSLLQYGGSANAE 635
           PLH +    ++  V+ LL  G          +  +H A+     +V   LL  G S N  
Sbjct: 324 PLHASAAQGDVHHVQSLLNHGHHHSKKDSIAWAAIHYASWYGSADVVEILLDAGCSPNLT 145

Query: 636 SVQGVTPLHLAAQEGHTEMVALLLSKQA-NGNLGNKSG 672
           + + +TPLH+AA++G  ++   L+  +A + NL +K G
Sbjct: 144 NSELLTPLHIAAKKGFPDVAEHLVQAEAIDLNLRDKDG 31

 Score = 37.7 bits (86), Expect = 0.047,   Method: Compositional matrix adjust.
 Identities = 27/97 (27%), Positives = 50/97 (51%), Gaps = 1/97 (1%)
 Frame = -3

Query: 53  LHLASKEGHVKMVVELLHKEIILETTTKKGNTALHIAALAGQDEVVRELVNYGANVNAQS 112
           LH ++ +G V  V  LL+              A+H A+  G  +VV  L++ G + N  +
Sbjct: 321 LHASAAQGDVHHVQSLLNHGHHHSKKDSIAWAAIHYASWYGSADVVEILLDAGCSPNLTN 142

Query: 113 QKGFTPLYMAAQENHLEVVKFLLENGA-NQNVATEDG 148
            +  TPL++AA++   +V + L++  A + N+  +DG
Sbjct: 141 SELLTPLHIAAKKGFPDVAEHLVQAEAIDLNLRDKDG 31

 Score = 35.0 bits (79), Expect = 0.30,   Method: Compositional matrix adjust.
 Identities = 29/106 (27%), Positives = 49/106 (46%), Gaps = 5/106 (4%)
 Frame = -3

Query: 151 PLAVALQQGHENVVAHLINYG----TKGKVRLPALHIAARNDDTRTAAVLLQNDPNPDVL 206
           PL  +  QG  + V  L+N+G     K  +   A+H A+         +LL    +P++ 
Sbjct: 324 PLHASAAQGDVHHVQSLLNHGHHHSKKDSIAWAAIHYASWYGSADVVEILLDAGCSPNLT 145

Query: 207 SKTGFTPLHIAAHYENLNVAQLLLNRGA-SVNFTPQNGITPLHIAS 251
           +    TPLHIAA     +VA+ L+   A  +N   ++G   + I +
Sbjct: 144 NSELLTPLHIAAKKGFPDVAEHLVQAEAIDLNLRDKDGKRAIDICT 7
>34789
          Length = 1249

 Score = 53.5 bits (127), Expect = 7e-07,   Method: Compositional matrix adjust.
 Identities = 47/167 (28%), Positives = 77/167 (46%), Gaps = 1/167 (0%)
 Frame = +3

Query: 164 VAHLIN-YGTKGKVRLPALHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYEN 222
           VAH +N  G+ G     AL +A  + +      LL+N  NP   S+ G   LH A   ++
Sbjct: 45  VAHFLNQMGSDGST---ALFMAVYDGNVELVDYLLKNGANPHFSSQHG-NFLHAAVLSQS 212

Query: 223 LNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETRTKDELTPLHC 282
           + + Q  L+ G  +N     G +PL + SR       R+L++ GA + +R +   TPL  
Sbjct: 213 VPLIQRALDLGCDINEHNMFGNSPLTLVSRLDLPEACRMLVEHGADLNSRDRYRETPLLA 392

Query: 283 AARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLL 329
           +   G    + +L+ HGA +     N  S I+ +   +    + LLL
Sbjct: 393 SVYFGCELNARLLIQHGASLDLVDDNHTSAIYWSIFNNRQRTLMLLL 533

 Score = 52.4 bits (124), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 38/143 (26%), Positives = 67/143 (46%)
 Frame = +3

Query: 633 NAESVQGVTPLHLAAQEGHTEMVALLLSKQANGNLGNKSGLTPLHLVSQEGHVPVADVLI 692
           N     G T L +A  +G+ E+V  LL   AN +  ++ G   LH       VP+    +
Sbjct: 60  NQMGSDGSTALFMAVYDGNVELVDYLLKNGANPHFSSQHG-NFLHAAVLSQSVPLIQRAL 236

Query: 693 KHGVTVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTD 752
             G  ++     G +PL + S     +  + L++H AD+N++ +   +PL  +   G   
Sbjct: 237 DLGCDINEHNMFGNSPLTLVSRLDLPEACRMLVEHGADLNSRDRYRETPLLASVYFGCEL 416

Query: 753 IVTLLLKNGASPNEVSSNGTTPL 775
              LL+++GAS + V  N T+ +
Sbjct: 417 NARLLIQHGASLDLVDDNHTSAI 485

 Score = 49.7 bits (117), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 44/160 (27%), Positives = 75/160 (46%)
 Frame = +3

Query: 242 NGITPLHIASRRGNVIMVRLLLDRGAQIETRTKDELTPLHCAARNGHVRISEILLDHGAP 301
           +G T L +A   GNV +V  LL  GA     ++     LH A  +  V + +  LD G  
Sbjct: 75  DGSTALFMAVYDGNVELVDYLLKNGANPHFSSQHG-NFLHAAVLSQSVPLIQRALDLGCD 251

Query: 302 IQAKTKNGLSPIHMAAQGDHLDCVRLLLQYNAEIDDITLDHLTPLHVAAHCGHHRVAKVL 361
           I      G SP+ + ++ D  +  R+L+++ A+++       TPL  + + G    A++L
Sbjct: 252 INEHNMFGNSPLTLVSRLDLPEACRMLVEHGADLNSRDRYRETPLLASVYFGCELNARLL 431

Query: 362 LDKGAKPNSRALNGFTPLHIACKKNHIRVMELLLKTGASI 401
           +  GA  +    N  + ++ +   N  R + LLL  GAS 
Sbjct: 432 IQHGASLDLVDDNHTSAIYWSIFNNRQRTLMLLLLAGASF 551

 Score = 47.4 bits (111), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 41/159 (25%), Positives = 70/159 (44%)
 Frame = +3

Query: 605 NGYTPLHIAAKQNQIEVARSLLQYGGSANAESVQGVTPLHLAAQEGHTEMVALLLSKQAN 664
           +G T L +A     +E+   LL+ G + +  S  G   LH A       ++   L    +
Sbjct: 75  DGSTALFMAVYDGNVELVDYLLKNGANPHFSSQHG-NFLHAAVLSQSVPLIQRALDLGCD 251

Query: 665 GNLGNKSGLTPLHLVSQEGHVPVADVLIKHGVTVDATTRMGYTPLHVASHYGNIKLVKFL 724
            N  N  G +PL LVS+        +L++HG  +++  R   TPL  + ++G     + L
Sbjct: 252 INEHNMFGNSPLTLVSRLDLPEACRMLVEHGADLNSRDRYRETPLLASVYFGCELNARLL 431

Query: 725 LQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGAS 763
           +QH A ++       S ++ +        + LLL  GAS
Sbjct: 432 IQHGASLDLVDDNHTSAIYWSIFNNRQRTLMLLLLAGAS 548

 Score = 42.4 bits (98), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 41/163 (25%), Positives = 77/163 (47%), Gaps = 4/163 (2%)
 Frame = +3

Query: 275 DELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYNAE 334
           D  T L  A  +G+V + + LL +GA     +++G + +H A     +  ++  L    +
Sbjct: 75  DGSTALFMAVYDGNVELVDYLLKNGANPHFSSQHG-NFLHAAVLSQSVPLIQRALDLGCD 251

Query: 335 IDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPL----HIACKKNHIRV 390
           I++  +   +PL + +        ++L++ GA  NSR     TPL    +  C+ N    
Sbjct: 252 INEHNMFGNSPLTLVSRLDLPEACRMLVEHGADLNSRDRYRETPLLASVYFGCELN---- 419

Query: 391 MELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGAS 433
             LL++ GAS+D V ++  + ++ + F      +  LL  GAS
Sbjct: 420 ARLLIQHGASLDLVDDNHTSAIYWSIFNNRQRTLMLLLLAGAS 548

 Score = 42.0 bits (97), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 45/189 (23%), Positives = 75/189 (39%)
 Frame = +3

Query: 355 HRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHIRVMELLLKTGASIDAVTESGLTPLHV 414
           H VA  L   G+       +G T L +A    ++ +++ LLK GA+    ++ G   LH 
Sbjct: 39  HSVAHFLNQMGS-------DGSTALFMAVYDGNVELVDYLLKNGANPHFSSQHG-NFLHA 194

Query: 415 ASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVXXXXXXXXXXXXXXXXXX 474
           A     +P+++  L  G   N  N+   +PL + +R    E                   
Sbjct: 195 AVLSQSVPLIQRALDLGCDINEHNMFGNSPLTLVSRLDLPEACRMLVEHGADLNSRDRYR 374

Query: 475 XTPLHCAARIGHTGMVKLLLENGASPNLATTAGHTPLHTAAREGHVDTALALLEKEASQA 534
            TPL  +   G     +LL+++GAS +L      + ++ +       T + LL   AS  
Sbjct: 375 ETPLLASVYFGCELNARLLIQHGASLDLVDDNHTSAIYWSIFNNRQRTLMLLLLAGAS-- 548

Query: 535 CMTKKGFTP 543
                 FTP
Sbjct: 549 ------FTP 557

 Score = 41.6 bits (96), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 45/195 (23%), Positives = 81/195 (41%)
 Frame = +3

Query: 108 VNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQNVATEDGFTPLAVALQQGHENVVAHL 167
           +N     G T L+MA  + ++E+V +LL+NGAN + +++ G    A  L Q         
Sbjct: 57  LNQMGSDGSTALFMAVYDGNVELVDYLLKNGANPHFSSQHGNFLHAAVLSQS-------- 212

Query: 168 INYGTKGKVRLPALHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQ 227
                     +P +            A+ L  D N    +  G +PL + +  +     +
Sbjct: 213 ----------VPLIQ----------RALDLGCDINEH--NMFGNSPLTLVSRLDLPEACR 326

Query: 228 LLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETRTKDELTPLHCAARNG 287
           +L+  GA +N   +   TPL  +   G  +  RLL+  GA ++    +  + ++ +  N 
Sbjct: 327 MLVEHGADLNSRDRYRETPLLASVYFGCELNARLLIQHGASLDLVDDNHTSAIYWSIFNN 506

Query: 288 HVRISEILLDHGAPI 302
             R   +LL  GA  
Sbjct: 507 RQRTLMLLLLAGASF 551

 Score = 41.2 bits (95), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 34/139 (24%), Positives = 66/139 (47%), Gaps = 4/139 (2%)
 Frame = +3

Query: 13  AADAATSFLRAARSGNLDKALDHLRNGVDINTCNQNGLNGLHLASKEGHVKMVVELLHKE 72
            +D +T+   A   GN++     L+NG + +  +Q+G N LH A     V ++   L   
Sbjct: 69  GSDGSTALFMAVYDGNVELVDYLLKNGANPHFSSQHG-NFLHAAVLSQSVPLIQRALDLG 245

Query: 73  IILETTTKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPL----YMAAQENHL 128
             +      GN+ L + +     E  R LV +GA++N++ +   TPL    Y   + N  
Sbjct: 246 CDINEHNMFGNSPLTLVSRLDLPEACRMLVEHGADLNSRDRYRETPLLASVYFGCELN-- 419

Query: 129 EVVKFLLENGANQNVATED 147
              + L+++GA+ ++  ++
Sbjct: 420 --ARLLIQHGASLDLVDDN 470

 Score = 39.7 bits (91), Expect = 0.012,   Method: Compositional matrix adjust.
 Identities = 34/135 (25%), Positives = 60/135 (44%)
 Frame = +3

Query: 672 GLTPLHLVSQEGHVPVADVLIKHGVTVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADV 731
           G T L +   +G+V + D L+K+G     +++ G   LH A    ++ L++  L    D+
Sbjct: 78  GSTALFMAVYDGNVELVDYLLKNGANPHFSSQHG-NFLHAAVLSQSVPLIQRALDLGCDI 254

Query: 732 NAKTKLGYSPLHQAAQQGHTDIVTLLLKNGASPNEVSSNGTTPLAIAKRLGYISVTDVLK 791
           N     G SPL   ++    +   +L+++GA  N       TPL  +   G     +   
Sbjct: 255 NEHNMFGNSPLTLVSRLDLPEACRMLVEHGADLNSRDRYRETPLLASVYFG--CELNARL 428

Query: 792 VVTDETSVVLVSDKH 806
           ++    S+ LV D H
Sbjct: 429 LIQHGASLDLVDDNH 473

 Score = 38.9 bits (89), Expect = 0.018,   Method: Compositional matrix adjust.
 Identities = 33/127 (25%), Positives = 60/127 (47%), Gaps = 4/127 (3%)
 Frame = +3

Query: 476 TPLHCAARIGHTGMVKLLLENGASPNLATTAGHTPLHTAAREGHVDTALALLEKEASQAC 535
           T L  A   G+  +V  LL+NGA+P+ ++  G+  LH A     +  ++ L+++     C
Sbjct: 84  TALFMAVYDGNVELVDYLLKNGANPHFSSQHGNF-LHAAV----LSQSVPLIQRALDLGC 248

Query: 536 MTKK----GFTPLHVAAKYGKVRLAELLLEHDAHPNAAGKNGLTPLHVAVHHNNLDIVKL 591
              +    G +PL + ++        +L+EH A  N+  +   TPL  +V+       +L
Sbjct: 249 DINEHNMFGNSPLTLVSRLDLPEACRMLVEHGADLNSRDRYRETPLLASVYFGCELNARL 428

Query: 592 LLPRGGS 598
           L+  G S
Sbjct: 429 LIQHGAS 449
>16561
          Length = 2029

 Score = 52.4 bits (124), Expect = 2e-06,   Method: Composition-based stats.
 Identities = 69/294 (23%), Positives = 119/294 (40%), Gaps = 39/294 (13%)
 Frame = -3

Query: 80   KKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGA 139
            + G+TALH +A   Q +V++ L++ GA +NA +  G + L++A  + H++ V  LL  G 
Sbjct: 2018 RDGDTALHYSAFGNQPDVLQLLLSKGAKINALNNGGCSTLHVAVNKQHIKCVHVLLNXGC 1839

Query: 140  NQNVATEDGFTPL-----------------AVALQQGHENVVAHLINYGTKGKVR-LPAL 181
            + N     G T L                  +AL    E  VA + +     +   LP  
Sbjct: 1838 DVNXQDAYGDTALHDAIGKRAVKSLTSLSITLALISPSETSVASMSSIMQP*RAMCLPRS 1659

Query: 182  HIAARND--------------------DTRTAAV-LLQNDPNPDVLSKTGFTPLHIAAHY 220
                  D                    DTR     LL+N    D+ +    TPL +A   
Sbjct: 1658 ASCTNVDRLWT*GKMMGFLHFTWLL*MDTRMLQQHLLRNRAEVDIRNNRQQTPLLLAVSQ 1479

Query: 221  ENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETRTKDELTPL 280
             + ++ +LL++  A +N + ++G T LH+A  R  V       +  +++    + +L   
Sbjct: 1478 GHSSLIELLVHAQADINVSDEDGDTCLHLALMRQTVAT-----EDSSRMLDSIRSQLGMG 1314

Query: 281  HCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYNAE 334
               A+ G   I+  L   GA + A  + G  P+ +         V +L Q+  E
Sbjct: 1313 EDEAQTG-AAIACYLAQQGASLTACNQQGKXPLDVTTD---TRTVEILQQFATE 1164

 Score = 51.6 bits (122), Expect = 3e-06,   Method: Composition-based stats.
 Identities = 75/297 (25%), Positives = 122/297 (41%), Gaps = 13/297 (4%)
 Frame = -3

Query: 307  KNGLSPIHMAAQGDHLDCVRLLLQYNAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGA 366
            ++G + +H +A G+  D ++LLL   A+I+ +     + LHVA +  H +   VLL+ G 
Sbjct: 2018 RDGDTALHYSAFGNQPDVLQLLLSKGAKINALNNGGCSTLHVAVNKQHIKCVHVLLNXGC 1839

Query: 367  KPNSRALNGFTPLHIACKKNHIRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKN 426
              N +   G T LH A  K   R ++ L     ++  ++ S  +   ++S M   P    
Sbjct: 1838 DVNXQDAYGDTALHDAIGK---RAVKSLTSLSITLALISPSETSVASMSSIMQ--P*RAM 1674

Query: 427  LLQRGAS-PNVSNV----KVETPLH------MAARAGHTEVXXXXXXXXXXXXXXXXXXX 475
             L R AS  NV  +    K+   LH      M  R     +                   
Sbjct: 1673 CLPRSASCTNVDRLWT*GKMMGFLHFTWLL*MDTRM----LQQHLLRNRAEVDIRNNRQQ 1506

Query: 476  TPLHCAARIGHTGMVKLLLENGASPNLATTAGHTPLHTAAREGHVDT--ALALLEKEASQ 533
            TPL  A   GH+ +++LL+   A  N++   G T LH A     V T  +  +L+   SQ
Sbjct: 1505 TPLLLAVSQGHSSLIELLVHAQADINVSDEDGDTCLHLALMRQTVATEDSSRMLDSIRSQ 1326

Query: 534  ACMTKKGFTPLHVAAKYGKVRLAELLLEHDAHPNAAGKNGLTPLHVAVHHNNLDIVK 590
              M +         A+ G   +A  L +  A   A  + G  PL V      ++I++
Sbjct: 1325 LGMGED-------EAQTGAA-IACYLAQQGASLTACNQQGKXPLDVTTDTRTVEILQ 1179

 Score = 51.2 bits (121), Expect = 4e-06,   Method: Composition-based stats.
 Identities = 53/216 (24%), Positives = 92/216 (42%), Gaps = 8/216 (3%)
 Frame = -3

Query: 571  KNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQIEVARSLLQYGG 630
            ++G T LH +   N  D+++LLL +G   ++    G + LH+A  +  I+    LL  G 
Sbjct: 2018 RDGDTALHYSAFGNQPDVLQLLLSKGAKINALNNGGCSTLHVAVNKQHIKCVHVLLNXGC 1839

Query: 631  SANAESVQGVTPLHLA----AQEGHTEM-VALLLSKQANGNLGNKSGLTP---LHLVSQE 682
              N +   G T LH A    A +  T + + L L   +  ++ + S +        + + 
Sbjct: 1838 DVNXQDAYGDTALHDAIGKRAVKSLTSLSITLALISPSETSVASMSSIMQP*RAMCLPRS 1659

Query: 683  GHVPVADVLIKHGVTVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPL 742
                  D L   G        MG+             L + LL+++A+V+ +     +PL
Sbjct: 1658 ASCTNVDRLWT*G------KMMGFLHFTWLL*MDTRMLQQHLLRNRAEVDIRNNRQQTPL 1497

Query: 743  HQAAQQGHTDIVTLLLKNGASPNEVSSNGTTPLAIA 778
              A  QGH+ ++ LL+   A  N    +G T L +A
Sbjct: 1496 LLAVSQGHSSLIELLVHAQADINVSDEDGDTCLHLA 1389

 Score = 48.1 bits (113), Expect = 3e-05,   Method: Composition-based stats.
 Identities = 71/299 (23%), Positives = 102/299 (34%), Gaps = 17/299 (5%)
 Frame = -3

Query: 374  NGFTPLHIACKKNHIRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGAS 433
            +G T LH +   N   V++LLL  GA I+A+   G + LHVA    H+  V  LL  G  
Sbjct: 2015 DGDTALHYSAFGNQPDVLQLLLSKGAKINALNNGGCSTLHVAVNKQHIKCVHVLLNXGCD 1836

Query: 434  PNVSNVKVETPLH--MAARAGHTEVXXXXXXXXXXXXXXXXXXXTPL------HCAARIG 485
             N  +   +T LH  +  RA  +                     + +       C  R  
Sbjct: 1835 VNXQDAYGDTALHDAIGKRAVKSLTSLSITLALISPSETSVASMSSIMQP*RAMCLPRSA 1656

Query: 486  HTGMVKLLLENGASPNLATTAGHTPLHTAAREGHVDTALALLEKEASQACMTKKGFTPLH 545
                V  L   G             + T   + H      LL   A       +  TPL 
Sbjct: 1655 SCTNVDRLWT*GKMMGFLHFTWLL*MDTRMLQQH------LLRNRAEVDIRNNRQQTPLL 1494

Query: 546  VAAKYGKVRLAELLLEHDAHPNAAGKNGLTPLHVAVHHNN---------LDIVKLLLPRG 596
            +A   G   L ELL+   A  N + ++G T LH+A+             LD ++  L  G
Sbjct: 1493 LAVSQGHSSLIELLVHAQADINVSDEDGDTCLHLALMRQTVATEDSSRMLDSIRSQLGMG 1314

Query: 597  GSPHSPAWNGYTPLHIAAKQNQIEVARSLLQYGGSANAESVQGVTPLHLAAQEGHTEMV 655
                               Q    +A  L Q G S  A + QG  PL +       E++
Sbjct: 1313 ED---------------EAQTGAAIACYLAQQGASLTACNQQGKXPLDVTTDTRTVEIL 1182

 Score = 45.1 bits (105), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 61/278 (21%), Positives = 99/278 (35%), Gaps = 62/278 (22%)
 Frame = -3

Query: 507  GHTPLHTAAREGHVDTALALLEKEASQACMTKKGFTPLHVAAKYGKVRLAELLLEHDAHP 566
            G T LH +A     D    LL K A    +   G + LHVA     ++   +LL      
Sbjct: 2012 GDTALHYSAFGNQPDVLQLLLSKGAKINALNNGGCSTLHVAVNKQHIKCVHVLLNXGCDV 1833

Query: 567  NAAGKNGLTPLHVAVHH------NNLDIV----------------------KLLLPRGGS 598
            N     G T LH A+         +L I                        + LPR  S
Sbjct: 1832 NXQDAYGDTALHDAIGKRAVKSLTSLSITLALISPSETSVASMSSIMQP*RAMCLPRSAS 1653

Query: 599  PHSP--AWN-----GYTPLHIAAKQNQIEVARSLLQYGGSANAESVQGVTPLHLAAQEGH 651
              +    W      G+         +   + + LL+     +  + +  TPL LA  +GH
Sbjct: 1652 CTNVDRLWT*GKMMGFLHFTWLL*MDTRMLQQHLLRNRAEVDIRNNRQQTPLLLAVSQGH 1473

Query: 652  TEMVALLLSKQANGNLGNKSGLTPLHLV-------------------SQEGH-------- 684
            + ++ LL+  QA+ N+ ++ G T LHL                    SQ G         
Sbjct: 1472 SSLIELLVHAQADINVSDEDGDTCLHLALMRQTVATEDSSRMLDSIRSQLGMGEDEAQTG 1293

Query: 685  VPVADVLIKHGVTVDATTRMGYTPLHVASHYGNIKLVK 722
              +A  L + G ++ A  + G  PL V +    +++++
Sbjct: 1292 AAIACYLAQQGASLTACNQQGKXPLDVTTDTRTVEILQ 1179

 Score = 43.9 bits (102), Expect = 6e-04,   Method: Composition-based stats.
 Identities = 54/218 (24%), Positives = 92/218 (42%), Gaps = 10/218 (4%)
 Frame = -3

Query: 538  KKGFTPLHVAAKYGKVRLAELLLEHDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGG 597
            + G T LH +A   +  + +LLL   A  NA    G + LHVAV+  ++  V +LL  G 
Sbjct: 2018 RDGDTALHYSAFGNQPDVLQLLLSKGAKINALNNGGCSTLHVAVNKQHIKCVHVLLNXGC 1839

Query: 598  SPHSPAWNGYTPLHIAAKQNQIEVARSLLQYGGSANAESVQGVTPLHLAAQEGHTEMV-- 655
              +     G T LH A  +  ++   SL        + ++  ++P   +     + M   
Sbjct: 1838 DVNXQDAYGDTALHDAIGKRAVKSLTSL--------SITLALISPSETSVASMSSIMQP* 1683

Query: 656  -ALLLSKQAN-GNL------GNKSGLTPLHLVSQEGHVPVADVLIKHGVTVDATTRMGYT 707
             A+ L + A+  N+      G   G      +       +   L+++   VD       T
Sbjct: 1682 RAMCLPRSASCTNVDRLWT*GKMMGFLHFTWLL*MDTRMLQQHLLRNRAEVDIRNNRQQT 1503

Query: 708  PLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQA 745
            PL +A   G+  L++ L+  QAD+N   + G + LH A
Sbjct: 1502 PLLLAVSQGHSSLIELLVHAQADINVSDEDGDTCLHLA 1389

 Score = 41.6 bits (96), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 27/73 (36%), Positives = 40/73 (54%), Gaps = 3/73 (4%)
 Frame = -2

Query: 33   LDHLRN--GVDINTCNQNGLNGLHLASKEGHVKMVVELLHK-EIILETTTKKGNTALHIA 89
            +D L N  G+D    N+ G N LH A+ +G+V     +LHK   I++     G +ALH+A
Sbjct: 1767 IDKLVNYPGIDFTFRNKRGFNVLHHAALKGNVFATERVLHKCRQIVDLRKDDGFSALHLA 1588

Query: 90   ALAGQDEVVRELV 102
            AL G  +V   L+
Sbjct: 1587 ALNGHKDVAAALI 1549

 Score = 40.4 bits (93), Expect = 0.006,   Method: Composition-based stats.
 Identities = 24/76 (31%), Positives = 36/76 (47%)
 Frame = -3

Query: 274  KDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYNA 333
            +D  T LH +A      + ++LL  GA I A    G S +H+A    H+ CV +LL    
Sbjct: 2018 RDGDTALHYSAFGNQPDVLQLLLSKGAKINALNNGGCSTLHVAVNKQHIKCVHVLLNXGC 1839

Query: 334  EIDDITLDHLTPLHVA 349
            +++       T LH A
Sbjct: 1838 DVNXQDAYGDTALHDA 1791

 Score = 35.8 bits (81), Expect = 0.15,   Method: Compositional matrix adjust.
 Identities = 34/142 (23%), Positives = 61/142 (42%), Gaps = 29/142 (20%)
 Frame = -3

Query: 36   LRNGVDINTCNQNGLNGLHLASKEGHVKMVVELLHKEIILETTTKKGNTALHIAAL---- 91
            LRN  +++  N      L LA  +GH  ++  L+H +  +  + + G+T LH+A +    
Sbjct: 1550 LRNRAEVDIRNNRQQTPLLLAVSQGHSSLIELLVHAQADINVSDEDGDTCLHLALMRQTV 1371

Query: 92   -----------------AGQDE------VVRELVNYGANVNAQSQKGFTPLYMAAQENHL 128
                              G+DE      +   L   GA++ A +Q+G  PL +      +
Sbjct: 1370 ATEDSSRMLDSIRSQLGMGEDEAQTGAAIACYLAQQGASLTACNQQGKXPLDVTTDTRTV 1191

Query: 129  EVV-KFLLENGA-NQNVATEDG 148
            E++ +F  E  A N  +  E+G
Sbjct: 1190 EILQQFATEFCASNTKIEEEEG 1125

 Score = 34.7 bits (78), Expect = 0.36,   Method: Composition-based stats.
 Identities = 20/54 (37%), Positives = 27/54 (50%)
 Frame = -3

Query: 36   LRNGVDINTCNQNGLNGLHLASKEGHVKMVVELLHKEIILETTTKKGNTALHIA 89
            L  G  IN  N  G + LH+A  + H+K V  LL+    +      G+TALH A
Sbjct: 1952 LSKGAKINALNNGGCSTLHVAVNKQHIKCVHVLLNXGCDVNXQDAYGDTALHDA 1791
>22305
          Length = 426

 Score = 50.4 bits (119), Expect = 6e-06,   Method: Compositional matrix adjust.
 Identities = 31/73 (42%), Positives = 35/73 (47%)
 Frame = -3

Query: 579 VAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQIEVARSLLQYGGSANAESVQ 638
           V+V  N  DI   LL RG S +     G  PLH A     +EV R LLQYG   N     
Sbjct: 367 VSVRVNAADITTALLERGCSANERNHWGILPLHEALCWENVEVGRVLLQYGADPNVPCET 188

Query: 639 GVTPLHLAAQEGH 651
            V PL  AA+ GH
Sbjct: 187 NVVPLTFAARTGH 149

 Score = 44.3 bits (103), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 27/67 (40%), Positives = 34/67 (50%)
 Frame = -3

Query: 224 NVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETRTKDELTPLHCA 283
           ++   LL RG S N     GI PLH A    NV + R+LL  GA      +  + PL  A
Sbjct: 343 DITTALLERGCSANERNHWGILPLHEALCWENVEVGRVLLQYGADPNVPCETNVVPLTFA 164

Query: 284 ARNGHVR 290
           AR GH+R
Sbjct: 163 ARTGHIR 143

 Score = 42.0 bits (97), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 25/73 (34%), Positives = 36/73 (49%)
 Frame = -3

Query: 381 IACKKNHIRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVK 440
           ++ + N   +   LL+ G S +     G+ PLH A    ++ + + LLQ GA PNV    
Sbjct: 367 VSVRVNAADITTALLERGCSANERNHWGILPLHEALCWENVEVGRVLLQYGADPNVPCET 188

Query: 441 VETPLHMAARAGH 453
              PL  AAR GH
Sbjct: 187 NVVPLTFAARTGH 149

 Score = 40.8 bits (94), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 21/74 (28%), Positives = 41/74 (55%)
 Frame = -3

Query: 612 IAAKQNQIEVARSLLQYGGSANAESVQGVTPLHLAAQEGHTEMVALLLSKQANGNLGNKS 671
           ++ + N  ++  +LL+ G SAN  +  G+ PLH A    + E+  +LL   A+ N+  ++
Sbjct: 367 VSVRVNAADITTALLERGCSANERNHWGILPLHEALCWENVEVGRVLLQYGADPNVPCET 188

Query: 672 GLTPLHLVSQEGHV 685
            + PL   ++ GH+
Sbjct: 187 NVVPLTFAARTGHI 146

 Score = 40.8 bits (94), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 25/79 (31%), Positives = 39/79 (49%), Gaps = 3/79 (3%)
 Frame = -3

Query: 675 PLHLVSQEGHVPVADV---LIKHGVTVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADV 731
           P +  S    V  AD+   L++ G + +     G  PLH A  + N+++ + LLQ+ AD 
Sbjct: 385 PCYTQSVSVRVNAADITTALLERGCSANERNHWGILPLHEALCWENVEVGRVLLQYGADP 206

Query: 732 NAKTKLGYSPLHQAAQQGH 750
           N   +    PL  AA+ GH
Sbjct: 205 NVPCETNVVPLTFAARTGH 149

 Score = 39.7 bits (91), Expect = 0.011,   Method: Compositional matrix adjust.
 Identities = 20/61 (32%), Positives = 29/61 (47%)
 Frame = -3

Query: 724 LLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGASPNEVSSNGTTPLAIAKRLGY 783
           LL+     N +   G  PLH+A    + ++  +LL+ GA PN        PL  A R G+
Sbjct: 328 LLERGCSANERNHWGILPLHEALCWENVEVGRVLLQYGADPNVPCETNVVPLTFAARTGH 149

Query: 784 I 784
           I
Sbjct: 148 I 146

 Score = 39.3 bits (90), Expect = 0.013,   Method: Compositional matrix adjust.
 Identities = 21/74 (28%), Positives = 37/74 (50%)
 Frame = -3

Query: 183 IAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFTPQN 242
           ++ R +       LL+   + +  +  G  PLH A  +EN+ V ++LL  GA  N   + 
Sbjct: 367 VSVRVNAADITTALLERGCSANERNHWGILPLHEALCWENVEVGRVLLQYGADPNVPCET 188

Query: 243 GITPLHIASRRGNV 256
            + PL  A+R G++
Sbjct: 187 NVVPLTFAARTGHI 146

 Score = 37.7 bits (86), Expect = 0.040,   Method: Compositional matrix adjust.
 Identities = 24/89 (26%), Positives = 38/89 (42%)
 Frame = -3

Query: 531 ASQACMTKKGFTPLHVAAKYGKVRLAELLLEHDAHPNAAGKNGLTPLHVAVHHNNLDIVK 590
           A+  C T+       V+ +     +   LLE     N     G+ PLH A+   N+++ +
Sbjct: 394 AAAPCYTQS------VSVRVNAADITTALLERGCSANERNHWGILPLHEALCWENVEVGR 233

Query: 591 LLLPRGGSPHSPAWNGYTPLHIAAKQNQI 619
           +LL  G  P+ P      PL  AA+   I
Sbjct: 232 VLLQYGADPNVPCETNVVPLTFAARTGHI 146

 Score = 36.6 bits (83), Expect = 0.085,   Method: Compositional matrix adjust.
 Identities = 21/66 (31%), Positives = 35/66 (53%)
 Frame = -3

Query: 291 ISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYNAEIDDITLDHLTPLHVAA 350
           I+  LL+ G     +   G+ P+H A   ++++  R+LLQY A+ +     ++ PL  AA
Sbjct: 340 ITTALLERGCSANERNHWGILPLHEALCWENVEVGRVLLQYGADPNVPCETNVVPLTFAA 161

Query: 351 HCGHHR 356
             GH R
Sbjct: 160 RTGHIR 143

 Score = 35.4 bits (80), Expect = 0.19,   Method: Compositional matrix adjust.
 Identities = 23/74 (31%), Positives = 33/74 (44%), Gaps = 3/74 (4%)
 Frame = -3

Query: 510 PLHT---AAREGHVDTALALLEKEASQACMTKKGFTPLHVAAKYGKVRLAELLLEHDAHP 566
           P +T   + R    D   ALLE+  S       G  PLH A  +  V +  +LL++ A P
Sbjct: 385 PCYTQSVSVRVNAADITTALLERGCSANERNHWGILPLHEALCWENVEVGRVLLQYGADP 206

Query: 567 NAAGKNGLTPLHVA 580
           N   +  + PL  A
Sbjct: 205 NVPCETNVVPLTFA 164

 Score = 33.1 bits (74), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 18/61 (29%), Positives = 29/61 (47%)
 Frame = -3

Query: 262 LLDRGAQIETRTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDH 321
           LL+RG     R    + PLH A    +V +  +LL +GA      +  + P+  AA+  H
Sbjct: 328 LLERGCSANERNHWGILPLHEALCWENVEVGRVLLQYGADPNVPCETNVVPLTFAARTGH 149

Query: 322 L 322
           +
Sbjct: 148 I 146

 Score = 31.6 bits (70), Expect = 2.8,   Method: Compositional matrix adjust.
 Identities = 24/76 (31%), Positives = 33/76 (43%)
 Frame = -3

Query: 481 AARIGHTGMVKLLLENGASPNLATTAGHTPLHTAAREGHVDTALALLEKEASQACMTKKG 540
           + R+    +   LLE G S N     G  PLH A    +V+    LL+  A      +  
Sbjct: 364 SVRVNAADITTALLERGCSANERNHWGILPLHEALCWENVEVGRVLLQYGADPNVPCETN 185

Query: 541 FTPLHVAAKYGKVRLA 556
             PL  AA+ G +RLA
Sbjct: 184 VVPLTFAARTGHIRLA 137

 Score = 31.2 bits (69), Expect = 3.7,   Method: Compositional matrix adjust.
 Identities = 18/47 (38%), Positives = 22/47 (46%)
 Frame = -3

Query: 343 LTPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHIR 389
           + PLH A    +  V +VLL  GA PN        PL  A +  HIR
Sbjct: 283 ILPLHEALCWENVEVGRVLLQYGADPNVPCETNVVPLTFAARTGHIR 143

 Score = 30.8 bits (68), Expect = 6.0,   Method: Compositional matrix adjust.
 Identities = 17/44 (38%), Positives = 24/44 (54%)
 Frame = -3

Query: 477 PLHCAARIGHTGMVKLLLENGASPNLATTAGHTPLHTAAREGHV 520
           PLH A    +  + ++LL+ GA PN+       PL  AAR GH+
Sbjct: 277 PLHEALCWENVEVGRVLLQYGADPNVPCETNVVPLTFAARTGHI 146
>15359
          Length = 780

 Score = 49.7 bits (117), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 35/92 (38%), Positives = 52/92 (56%), Gaps = 3/92 (3%)
 Frame = +1

Query: 315 MAAQGDHLDCVRLLLQYN--AEIDDITLDHLTPLHVAAHCGHHRVAKVLLDK-GAKPNSR 371
           ++A  D+ +  RLL +    A++ DI  +  T LH AA  G   V K+L +K G + N R
Sbjct: 265 VSATADYHEMFRLLNKNARLAKVKDIA-NGYTALHWAAKFGKPEVVKMLANKIGVEINQR 441

Query: 372 ALNGFTPLHIACKKNHIRVMELLLKTGASIDA 403
           +  G+TPLH+A    H  ++ELL+ TG   DA
Sbjct: 442 SHGGYTPLHLAAIHGHEDIIELLV-TGYKADA 534

 Score = 49.7 bits (117), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 24/55 (43%), Positives = 35/55 (63%), Gaps = 1/55 (1%)
 Frame = +1

Query: 705 GYTPLHVASHYGNIKLVKFLLQH-QADVNAKTKLGYSPLHQAAQQGHTDIVTLLL 758
           GYT LH A+ +G  ++VK L      ++N ++  GY+PLH AA  GH DI+ LL+
Sbjct: 349 GYTALHWAAKFGKPEVVKMLANKIGVEINQRSHGGYTPLHLAAIHGHEDIIELLV 513

 Score = 48.9 bits (115), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 31/70 (44%), Positives = 43/70 (61%), Gaps = 2/70 (2%)
 Frame = +1

Query: 605 NGYTPLHIAAKQNQIEVARSLL-QYGGSANAESVQGVTPLHLAAQEGHTEMVALLLSK-Q 662
           NGYT LH AAK  + EV + L  + G   N  S  G TPLHLAA  GH +++ LL++  +
Sbjct: 346 NGYTALHWAAKFGKPEVVKMLANKIGVEINQRSHGGYTPLHLAAIHGHEDIIELLVTGYK 525

Query: 663 ANGNLGNKSG 672
           A+ N+ + SG
Sbjct: 526 ADANIRDYSG 555

 Score = 47.8 bits (112), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 24/55 (43%), Positives = 36/55 (65%), Gaps = 1/55 (1%)
 Frame = +1

Query: 82  GNTALHIAALAGQDEVVRELVN-YGANVNAQSQKGFTPLYMAAQENHLEVVKFLL 135
           G TALH AA  G+ EVV+ L N  G  +N +S  G+TPL++AA   H ++++ L+
Sbjct: 349 GYTALHWAAKFGKPEVVKMLANKIGVEINQRSHGGYTPLHLAAIHGHEDIIELLV 513

 Score = 43.9 bits (102), Expect = 6e-04,   Method: Compositional matrix adjust.
 Identities = 27/71 (38%), Positives = 41/71 (57%), Gaps = 3/71 (4%)
 Frame = +1

Query: 229 LLNRGASVNFTPQ--NGITPLHIASRRGNVIMVRLLLDR-GAQIETRTKDELTPLHCAAR 285
           LLN+ A +       NG T LH A++ G   +V++L ++ G +I  R+    TPLH AA 
Sbjct: 301 LLNKNARLAKVKDIANGYTALHWAAKFGKPEVVKMLANKIGVEINQRSHGGYTPLHLAAI 480

Query: 286 NGHVRISEILL 296
           +GH  I E+L+
Sbjct: 481 HGHEDIIELLV 513

 Score = 42.4 bits (98), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 22/55 (40%), Positives = 32/55 (58%), Gaps = 1/55 (1%)
 Frame = +1

Query: 540 GFTPLHVAAKYGKVRLAELLLEH-DAHPNAAGKNGLTPLHVAVHHNNLDIVKLLL 593
           G+T LH AAK+GK  + ++L        N     G TPLH+A  H + DI++LL+
Sbjct: 349 GYTALHWAAKFGKPEVVKMLANKIGVEINQRSHGGYTPLHLAAIHGHEDIIELLV 513

 Score = 42.0 bits (97), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 29/84 (34%), Positives = 46/84 (54%), Gaps = 3/84 (3%)
 Frame = +1

Query: 348 VAAHCGHHRVAKVLLDKGAK--PNSRALNGFTPLHIACKKNHIRVMELLL-KTGASIDAV 404
           V+A   +H + + LL+K A+        NG+T LH A K     V+++L  K G  I+  
Sbjct: 265 VSATADYHEMFR-LLNKNARLAKVKDIANGYTALHWAAKFGKPEVVKMLANKIGVEINQR 441

Query: 405 TESGLTPLHVASFMGHLPIVKNLL 428
           +  G TPLH+A+  GH  I++ L+
Sbjct: 442 SHGGYTPLHLAAIHGHEDIIELLV 513

 Score = 39.7 bits (91), Expect = 0.013,   Method: Compositional matrix adjust.
 Identities = 23/69 (33%), Positives = 40/69 (57%), Gaps = 2/69 (2%)
 Frame = +1

Query: 672 GLTPLHLVSQEGHVPVADVLI-KHGVTVDATTRMGYTPLHVASHYGNIKLVKFLLQ-HQA 729
           G T LH  ++ G   V  +L  K GV ++  +  GYTPLH+A+ +G+  +++ L+  ++A
Sbjct: 349 GYTALHWAAKFGKPEVVKMLANKIGVEINQRSHGGYTPLHLAAIHGHEDIIELLVTGYKA 528

Query: 730 DVNAKTKLG 738
           D N +   G
Sbjct: 529 DANIRDYSG 555

 Score = 39.3 bits (90), Expect = 0.017,   Method: Compositional matrix adjust.
 Identities = 25/68 (36%), Positives = 35/68 (51%), Gaps = 1/68 (1%)
 Frame = +1

Query: 637 VQGVTPLHLAAQEGHTEMVALLLSK-QANGNLGNKSGLTPLHLVSQEGHVPVADVLIKHG 695
             G T LH AA+ G  E+V +L +K     N  +  G TPLHL +  GH  + ++L+  G
Sbjct: 343 ANGYTALHWAAKFGKPEVVKMLANKIGVEINQRSHGGYTPLHLAAIHGHEDIIELLVT-G 519

Query: 696 VTVDATTR 703
              DA  R
Sbjct: 520 YKADANIR 543

 Score = 39.3 bits (90), Expect = 0.017,   Method: Compositional matrix adjust.
 Identities = 32/98 (32%), Positives = 47/98 (47%), Gaps = 8/98 (8%)
 Frame = +1

Query: 88  IAALAGQDEVVRELVNYGANVNAQSQK------GFTPLYMAAQENHLEVVKFLLEN-GAN 140
           ++A A   E+ R L     N NA+  K      G+T L+ AA+    EVVK L    G  
Sbjct: 265 VSATADYHEMFRLL-----NKNARLAKVKDIANGYTALHWAAKFGKPEVVKMLANKIGVE 429

Query: 141 QNVATEDGFTPLAVALQQGHENVVAHLI-NYGTKGKVR 177
            N  +  G+TPL +A   GHE+++  L+  Y     +R
Sbjct: 430 INQRSHGGYTPLHLAAIHGHEDIIELLVTGYKADANIR 543

 Score = 37.0 bits (84), Expect = 0.075,   Method: Compositional matrix adjust.
 Identities = 21/47 (44%), Positives = 26/47 (55%), Gaps = 1/47 (2%)
 Frame = +1

Query: 476 TPLHCAARIGHTGMVKLLLEN-GASPNLATTAGHTPLHTAAREGHVD 521
           T LH AA+ G   +VK+L    G   N  +  G+TPLH AA  GH D
Sbjct: 355 TALHWAAKFGKPEVVKMLANKIGVEINQRSHGGYTPLHLAAIHGHED 495
>35952
          Length = 1624

 Score = 49.7 bits (117), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 55/170 (32%), Positives = 72/170 (42%), Gaps = 8/170 (4%)
 Frame = -1

Query: 180  ALHIAARNDDTR-------TAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQ-LLLN 231
             LH  A  D  R         A +  N   PD   K+G T LH A   ++L VA  LL+ 
Sbjct: 1078 GLHXGAPGDSVRQCGHAAYVGAGVRANVDLPD--GKSGRTALHHAVELDDLPVAGFLLME 905

Query: 232  RGASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETRTKDELTPLHCAARNGHVRI 291
              A VN    +G TPLH+A  RG + MV LL+  GA   T  ++E  P       G    
Sbjct: 904  ANADVNARCFDGNTPLHVACCRGLIGMVALLMTAGAL--TDVENEEIPPEDKEEAG---- 743

Query: 292  SEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYNAEIDDITLD 341
                   G     K + GL P   AA  D L  +R+L+   A  +D+  D
Sbjct: 742  -------GETGSRKCRRGLLPRDYAAGKDRLRILRMLMGDLATEEDLNSD 614

 Score = 36.2 bits (82), Expect(2) = 3e-04,   Method: Compositional matrix adjust.
 Identities = 24/69 (34%), Positives = 38/69 (55%), Gaps = 1/69 (1%)
 Frame = -1

Query: 374 NGFTPLHIACKKNHIRVME-LLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGA 432
           +G T LH A + + + V   LL++  A ++A    G TPLHVA   G + +V  L+  GA
Sbjct: 976 SGRTALHHAVELDDLPVAGFLLMEANADVNARCFDGNTPLHVACCRGLIGMVALLMTAGA 797

Query: 433 SPNVSNVKV 441
             +V N ++
Sbjct: 796 LTDVENEEI 770

 Score = 28.1 bits (61), Expect(2) = 3e-04,   Method: Compositional matrix adjust.
 Identities = 17/67 (25%), Positives = 34/67 (50%), Gaps = 11/67 (16%)
 Frame = -2

Query: 307  KNGLSPIHMAAQGDHLDCVRLLLQY----------NAEIDDITLD-HLTPLHVAAHCGHH 355
            +NG +P H+A     L+ ++ L++Y            E+D +  +   TP+H+A  CG  
Sbjct: 1215 RNGNTPAHLAVLNSSLEALQSLVKYLRPGVTAANPFPELDYLNYE*DYTPVHLATQCGSV 1036

Query: 356  RVAKVLL 362
             + ++L+
Sbjct: 1035 DMLRMLV 1015

 Score = 40.8 bits (94), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 30/89 (33%), Positives = 43/89 (48%), Gaps = 1/89 (1%)
 Frame = -1

Query: 675  PLHLVSQEGHVPVADVLIKHGVTVDATTRMGYTPLHVASHYGNIKLVKFLL-QHQADVNA 733
            P   V Q GH       ++  V +    + G T LH A    ++ +  FLL +  ADVNA
Sbjct: 1060 PGDSVRQCGHAAYVGAGVRANVDL-PDGKSGRTALHHAVELDDLPVAGFLLMEANADVNA 884

Query: 734  KTKLGYSPLHQAAQQGHTDIVTLLLKNGA 762
            +   G +PLH A  +G   +V LL+  GA
Sbjct: 883  RCFDGNTPLHVACCRGLIGMVALLMTAGA 797

 Score = 35.0 bits (79), Expect(2) = 0.005,   Method: Compositional matrix adjust.
 Identities = 21/68 (30%), Positives = 36/68 (52%), Gaps = 1/68 (1%)
 Frame = -1

Query: 570 GKNGLTPLHVAVHHNNLDIVKLLLPRGGSP-HSPAWNGYTPLHIAAKQNQIEVARSLLQY 628
           GK+G T LH AV  ++L +   LL    +  ++  ++G TPLH+A  +  I +   L+  
Sbjct: 982 GKSGRTALHHAVELDDLPVAGFLLMEANADVNARCFDGNTPLHVACCRGLIGMVALLMTA 803

Query: 629 GGSANAES 636
           G   + E+
Sbjct: 802 GALTDVEN 779

 Score = 24.6 bits (52), Expect(2) = 0.005,   Method: Compositional matrix adjust.
 Identities = 21/77 (27%), Positives = 31/77 (40%), Gaps = 12/77 (15%)
 Frame = -2

Query: 497  GASPNLATTAGHTPLHTAAREGHVDTALALLEKEASQACMTKKGF------------TPL 544
            G  P+LA   G+TP H A     ++ AL  L K           F            TP+
Sbjct: 1239 GRDPSLADRNGNTPAHLAVLNSSLE-ALQSLVKYLRPGVTAANPFPELDYLNYE*DYTPV 1063

Query: 545  HVAAKYGKVRLAELLLE 561
            H+A + G V +  +L+ 
Sbjct: 1062 HLATQCGSVDMLRMLVR 1012

 Score = 40.4 bits (93), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 25/64 (39%), Positives = 33/64 (51%), Gaps = 1/64 (1%)
 Frame = -1

Query: 344 TPLHVAAHCGHHRVAKVLL-DKGAKPNSRALNGFTPLHIACKKNHIRVMELLLKTGASID 402
           T LH A       VA  LL +  A  N+R  +G TPLH+AC +  I ++ LL+  GA  D
Sbjct: 967 TALHHAVELDDLPVAGFLLMEANADVNARCFDGNTPLHVACCRGLIGMVALLMTAGALTD 788

Query: 403 AVTE 406
              E
Sbjct: 787 VENE 776

 Score = 39.7 bits (91), Expect = 0.011,   Method: Compositional matrix adjust.
 Identities = 34/122 (27%), Positives = 53/122 (43%), Gaps = 1/122 (0%)
 Frame = -1

Query: 605 NGYTPLHIAAKQNQIEVARSLL-QYGGSANAESVQGVTPLHLAAQEGHTEMVALLLSKQA 663
           +G T LH A + + + VA  LL +     NA    G TPLH+A   G   MVALL++  A
Sbjct: 976 SGRTALHHAVELDDLPVAGFLLMEANADVNARCFDGNTPLHVACCRGLIGMVALLMTAGA 797

Query: 664 NGNLGNKSGLTPLHLVSQEGHVPVADVLIKHGVTVDATTRMGYTPLHVASHYGNIKLVKF 723
             ++ N+              +P  D     G T     R G  P   A+    +++++ 
Sbjct: 796 LTDVENE-------------EIPPEDKEEAGGETGSRKCRRGLLPRDYAAGKDRLRILRM 656

Query: 724 LL 725
           L+
Sbjct: 655 LM 650

 Score = 35.0 bits (79), Expect = 0.29,   Method: Compositional matrix adjust.
 Identities = 30/80 (37%), Positives = 40/80 (50%), Gaps = 2/80 (2%)
 Frame = -1

Query: 648  QEGHTEMVALLLSKQANGNL-GNKSGLTPLHLVSQEGHVPVAD-VLIKHGVTVDATTRMG 705
            Q GH   V      +AN +L   KSG T LH   +   +PVA  +L++    V+A    G
Sbjct: 1042 QCGHAAYVGA--GVRANVDLPDGKSGRTALHHAVELDDLPVAGFLLMEANADVNARCFDG 869

Query: 706  YTPLHVASHYGNIKLVKFLL 725
             TPLHVA   G I +V  L+
Sbjct: 868  NTPLHVACCRGLIGMVALLM 809

 Score = 34.3 bits (77), Expect = 0.50,   Method: Compositional matrix adjust.
 Identities = 24/60 (40%), Positives = 33/60 (55%), Gaps = 1/60 (1%)
 Frame = -1

Query: 538 KKGFTPLHVAAKYGKVRLAE-LLLEHDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRG 596
           K G T LH A +   + +A  LL+E +A  NA   +G TPLHVA     + +V LL+  G
Sbjct: 979 KSGRTALHHAVELDDLPVAGFLLMEANADVNARCFDGNTPLHVACCRGLIGMVALLMTAG 800

 Score = 32.0 bits (71), Expect = 2.2,   Method: Compositional matrix adjust.
 Identities = 21/66 (31%), Positives = 33/66 (50%), Gaps = 11/66 (16%)
 Frame = -2

Query: 605  NGYTPLHIAAKQNQIEVARSLLQY--GGSANAESVQGV---------TPLHLAAQEGHTE 653
            NG TP H+A   + +E  +SL++Y   G   A     +         TP+HLA Q G  +
Sbjct: 1212 NGNTPAHLAVLNSSLEALQSLVKYLRPGVTAANPFPELDYLNYE*DYTPVHLATQCGSVD 1033

Query: 654  MVALLL 659
            M+ +L+
Sbjct: 1032 MLRMLV 1015

 Score = 31.6 bits (70), Expect = 3.0,   Method: Compositional matrix adjust.
 Identities = 24/77 (31%), Positives = 42/77 (54%), Gaps = 12/77 (15%)
 Frame = -2

Query: 566  PNAAGKNGLTPLHVAVHHNNLD----IVKLLLPRGGSPHSPAWN--------GYTPLHIA 613
            P+ A +NG TP H+AV +++L+    +VK L P G +  +P            YTP+H+A
Sbjct: 1230 PSLADRNGNTPAHLAVLNSSLEALQSLVKYLRP-GVTAANPFPELDYLNYE*DYTPVHLA 1054

Query: 614  AKQNQIEVARSLLQYGG 630
             +   +++ R L++  G
Sbjct: 1053 TQCGSVDMLRMLVRGSG 1003

 Score = 31.2 bits (69), Expect = 4.0,   Method: Compositional matrix adjust.
 Identities = 24/69 (34%), Positives = 34/69 (49%), Gaps = 1/69 (1%)
 Frame = -1

Query: 80  KKGNTALHIAALAGQDEVVRELV-NYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENG 138
           K G TALH A       V   L+    A+VNA+   G TPL++A     + +V  L+  G
Sbjct: 979 KSGRTALHHAVELDDLPVAGFLLMEANADVNARCFDGNTPLHVACCRGLIGMVALLMTAG 800

Query: 139 ANQNVATED 147
           A  +V  E+
Sbjct: 799 ALTDVENEE 773
>30463
          Length = 412

 Score = 49.3 bits (116), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 29/87 (33%), Positives = 43/87 (49%)
 Frame = -1

Query: 671 SGLTPLHLVSQEGHVPVADVLIKHGVTVDATTRMGYTPLHVASHYGNIKLVKFLLQHQAD 730
           +G T  HL +  GH     VL   G ++D  T    TPLH+AS  G+I+ VK L+ ++A 
Sbjct: 391 TGYTATHLAAMNGHSNAVMVLNIMGASIDCRTVDKQTPLHLASSAGHIECVKCLVANKAS 212

Query: 731 VNAKTKLGYSPLHQAAQQGHTDIVTLL 757
           + A+     +    A Q G  D+   L
Sbjct: 211 LTAEDAFSRTAYDLADQYGQNDVADFL 131

 Score = 48.5 bits (114), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 34/91 (37%), Positives = 50/91 (54%), Gaps = 2/91 (2%)
 Frame = -1

Query: 75  LETTTKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFL 134
           LET T  G TA H+AA+ G    V  L   GA+++ ++    TPL++A+   H+E VK L
Sbjct: 403 LETPT--GYTATHLAAMNGHSNAVMVLNIMGASIDCRTVDKQTPLHLASSAGHIECVKCL 230

Query: 135 LENGANQNVATEDGFTPLAVAL--QQGHENV 163
           + N A  ++  ED F+  A  L  Q G  +V
Sbjct: 229 VANKA--SLTAEDAFSRTAYDLADQYGQNDV 143

 Score = 48.1 bits (113), Expect = 3e-05,   Method: Composition-based stats.
 Identities = 29/82 (35%), Positives = 40/82 (48%)
 Frame = -1

Query: 375 GFTPLHIACKKNHIRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASP 434
           G+T  H+A    H   + +L   GASID  T    TPLH+AS  GH+  VK L+   AS 
Sbjct: 388 GYTATHLAAMNGHSNAVMVLNIMGASIDCRTVDKQTPLHLASSAGHIECVKCLVANKASL 209

Query: 435 NVSNVKVETPLHMAARAGHTEV 456
              +    T   +A + G  +V
Sbjct: 208 TAEDAFSRTAYDLADQYGQNDV 143

 Score = 48.1 bits (113), Expect = 3e-05,   Method: Composition-based stats.
 Identities = 30/86 (34%), Positives = 39/86 (45%)
 Frame = -1

Query: 606 GYTPLHIAAKQNQIEVARSLLQYGGSANAESVQGVTPLHLAAQEGHTEMVALLLSKQANG 665
           GYT  H+AA          L   G S +  +V   TPLHLA+  GH E V  L++ +A+ 
Sbjct: 388 GYTATHLAAMNGHSNAVMVLNIMGASIDCRTVDKQTPLHLASSAGHIECVKCLVANKASL 209

Query: 666 NLGNKSGLTPLHLVSQEGHVPVADVL 691
              +    T   L  Q G   VAD L
Sbjct: 208 TAEDAFSRTAYDLADQYGQNDVADFL 131

 Score = 46.2 bits (108), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 28/90 (31%), Positives = 40/90 (44%)
 Frame = -1

Query: 635 ESVQGVTPLHLAAQEGHTEMVALLLSKQANGNLGNKSGLTPLHLVSQEGHVPVADVLIKH 694
           E+  G T  HLAA  GH+  V +L    A+ +       TPLHL S  GH+     L+ +
Sbjct: 400 ETPTGYTATHLAAMNGHSNAVMVLNIMGASIDCRTVDKQTPLHLASSAGHIECVKCLVAN 221

Query: 695 GVTVDATTRMGYTPLHVASHYGNIKLVKFL 724
             ++ A      T   +A  YG   +  FL
Sbjct: 220 KASLTAEDAFSRTAYDLADQYGQNDVADFL 131

 Score = 44.7 bits (104), Expect = 4e-04,   Method: Composition-based stats.
 Identities = 28/84 (33%), Positives = 41/84 (48%)
 Frame = -1

Query: 476 TPLHCAARIGHTGMVKLLLENGASPNLATTAGHTPLHTAAREGHVDTALALLEKEASQAC 535
           T  H AA  GH+  V +L   GAS +  T    TPLH A+  GH++    L+  +AS   
Sbjct: 382 TATHLAAMNGHSNAVMVLNIMGASIDCRTVDKQTPLHLASSAGHIECVKCLVANKASLTA 203

Query: 536 MTKKGFTPLHVAAKYGKVRLAELL 559
                 T   +A +YG+  +A+ L
Sbjct: 202 EDAFSRTAYDLADQYGQNDVADFL 131

 Score = 43.5 bits (101), Expect = 7e-04,   Method: Composition-based stats.
 Identities = 26/84 (30%), Positives = 40/84 (47%)
 Frame = -1

Query: 278 TPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYNAEIDD 337
           T  H AA NGH     +L   GA I  +T +  +P+H+A+   H++CV+ L+   A +  
Sbjct: 382 TATHLAAMNGHSNAVMVLNIMGASIDCRTVDKQTPLHLASSAGHIECVKCLVANKASLTA 203

Query: 338 ITLDHLTPLHVAAHCGHHRVAKVL 361
                 T   +A   G + VA  L
Sbjct: 202 EDAFSRTAYDLADQYGQNDVADFL 131

 Score = 43.1 bits (100), Expect = 0.001,   Method: Composition-based stats.
 Identities = 30/99 (30%), Positives = 48/99 (48%)
 Frame = -1

Query: 239 TPQNGITPLHIASRRGNVIMVRLLLDRGAQIETRTKDELTPLHCAARNGHVRISEILLDH 298
           TP  G T  H+A+  G+   V +L   GA I+ RT D+ TPLH A+  GH+   + L+ +
Sbjct: 397 TP-TGYTATHLAAMNGHSNAVMVLNIMGASIDCRTVDKQTPLHLASSAGHIECVKCLVAN 221

Query: 299 GAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYNAEIDD 337
            A + A+     +   +A Q    D    L     ++D+
Sbjct: 220 KASLTAEDAFSRTAYDLADQYGQNDVADFLHHCLLDLDN 104

 Score = 41.2 bits (95), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 22/52 (42%), Positives = 29/52 (55%)
 Frame = -1

Query: 405 TESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEV 456
           T +G T  H+A+  GH   V  L   GAS +   V  +TPLH+A+ AGH E 
Sbjct: 397 TPTGYTATHLAAMNGHSNAVMVLNIMGASIDCRTVDKQTPLHLASSAGHIEC 242

 Score = 40.4 bits (93), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 28/89 (31%), Positives = 41/89 (46%)
 Frame = -1

Query: 702 TRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNG 761
           T  GYT  H+A+  G+   V  L    A ++ +T    +PLH A+  GH + V  L+ N 
Sbjct: 397 TPTGYTATHLAAMNGHSNAVMVLNIMGASIDCRTVDKQTPLHLASSAGHIECVKCLVANK 218

Query: 762 ASPNEVSSNGTTPLAIAKRLGYISVTDVL 790
           AS     +   T   +A + G   V D L
Sbjct: 217 ASLTAEDAFSRTAYDLADQYGQNDVADFL 131

 Score = 39.7 bits (91), Expect = 0.013,   Method: Composition-based stats.
 Identities = 22/60 (36%), Positives = 31/60 (51%)
 Frame = -1

Query: 344 TPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHIRVMELLLKTGASIDA 403
           T  H+AA  GH     VL   GA  + R ++  TPLH+A    HI  ++ L+   AS+ A
Sbjct: 382 TATHLAAMNGHSNAVMVLNIMGASIDCRTVDKQTPLHLASSAGHIECVKCLVANKASLTA 203

 Score = 38.5 bits (88), Expect = 0.028,   Method: Composition-based stats.
 Identities = 25/89 (28%), Positives = 43/89 (48%)
 Frame = -1

Query: 207 SKTGFTPLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDRG 266
           + TG+T  H+AA   + N   +L   GAS++    +  TPLH+AS  G++  V+ L+   
Sbjct: 397 TPTGYTATHLAAMNGHSNAVMVLNIMGASIDCRTVDKQTPLHLASSAGHIECVKCLVANK 218

Query: 267 AQIETRTKDELTPLHCAARNGHVRISEIL 295
           A +        T    A + G   +++ L
Sbjct: 217 ASLTAEDAFSRTAYDLADQYGQNDVADFL 131

 Score = 38.1 bits (87), Expect = 0.034,   Method: Compositional matrix adjust.
 Identities = 23/62 (37%), Positives = 32/62 (51%)
 Frame = -1

Query: 301 PIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYNAEIDDITLDHLTPLHVAAHCGHHRVAKV 360
           P   +T  G +  H+AA   H + V +L    A ID  T+D  TPLH+A+  GH    K 
Sbjct: 412 P*TLETPTGYTATHLAAMNGHSNAVMVLNIMGASIDCRTVDKQTPLHLASSAGHIECVKC 233

Query: 361 LL 362
           L+
Sbjct: 232 LV 227

 Score = 37.7 bits (86), Expect = 0.047,   Method: Composition-based stats.
 Identities = 29/88 (32%), Positives = 42/88 (47%), Gaps = 2/88 (2%)
 Frame = -1

Query: 49  GLNGLHLASKEGHVK--MVVELLHKEIILETTTKKGNTALHIAALAGQDEVVRELVNYGA 106
           G    HLA+  GH    MV+ ++   I   T  K+  T LH+A+ AG  E V+ LV   A
Sbjct: 388 GYTATHLAAMNGHSNAVMVLNIMGASIDCRTVDKQ--TPLHLASSAGHIECVKCLVANKA 215

Query: 107 NVNAQSQKGFTPLYMAAQENHLEVVKFL 134
           ++ A+     T   +A Q    +V  FL
Sbjct: 214 SLTAEDAFSRTAYDLADQYGQNDVADFL 131

 Score = 37.0 bits (84), Expect = 0.072,   Method: Compositional matrix adjust.
 Identities = 27/91 (29%), Positives = 39/91 (42%)
 Frame = -1

Query: 502 LATTAGHTPLHTAAREGHVDTALALLEKEASQACMTKKGFTPLHVAAKYGKVRLAELLLE 561
           L T  G+T  H AA  GH +  + L    AS  C T    TPLH+A+  G +   + L+ 
Sbjct: 403 LETPTGYTATHLAAMNGHSNAVMVLNIMGASIDCRTVDKQTPLHLASSAGHIECVKCLVA 224

Query: 562 HDAHPNAAGKNGLTPLHVAVHHNNLDIVKLL 592
           + A   A      T   +A  +   D+   L
Sbjct: 223 NKASLTAEDAFSRTAYDLADQYGQNDVADFL 131

 Score = 36.6 bits (83), Expect = 0.099,   Method: Composition-based stats.
 Identities = 25/86 (29%), Positives = 37/86 (43%)
 Frame = -1

Query: 573 GLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQIEVARSLLQYGGSA 632
           G T  H+A  + + + V +L   G S      +  TPLH+A+    IE  + L+    S 
Sbjct: 388 GYTATHLAAMNGHSNAVMVLNIMGASIDCRTVDKQTPLHLASSAGHIECVKCLVANKASL 209

Query: 633 NAESVQGVTPLHLAAQEGHTEMVALL 658
            AE     T   LA Q G  ++   L
Sbjct: 208 TAEDAFSRTAYDLADQYGQNDVADFL 131

 Score = 35.4 bits (80), Expect = 0.20,   Method: Compositional matrix adjust.
 Identities = 20/57 (35%), Positives = 30/57 (52%)
 Frame = -1

Query: 734 KTKLGYSPLHQAAQQGHTDIVTLLLKNGASPNEVSSNGTTPLAIAKRLGYISVTDVL 790
           +T  GY+  H AA  GH++ V +L   GAS +  + +  TPL +A   G+I     L
Sbjct: 400 ETPTGYTATHLAAMNGHSNAVMVLNIMGASIDCRTVDKQTPLHLASSAGHIECVKCL 230
>28691
          Length = 562

 Score = 48.5 bits (114), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 34/91 (37%), Positives = 52/91 (57%), Gaps = 5/91 (5%)
 Frame = +1

Query: 79  TKKGNTALHIAALAGQDEVVRELVNYGANVNAQ---SQKGFTPLYMAAQ--ENHLEVVKF 133
           +K G  ALH+AA     + +  LV  GA+VNA+   + KG T L+ A     ++++ V  
Sbjct: 109 SKSGLPALHLAAKNKHVDCIPVLVQAGADVNAKGPSTIKGNTALHEAVSVGASNVDSVDA 288

Query: 134 LLENGANQNVATEDGFTPLAVALQQGHENVV 164
           LL  GA+QN+  E G T   +A + G+EN+V
Sbjct: 289 LLSCGADQNIXNEKGETAYDLASKAGYENIV 381

 Score = 45.8 bits (107), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 33/91 (36%), Positives = 47/91 (51%), Gaps = 5/91 (5%)
 Frame = +1

Query: 669 NKSGLTPLHLVSQEGHVPVADVLIKHGVTVDA---TTRMGYTPLHVASHYG--NIKLVKF 723
           +KSGL  LHL ++  HV    VL++ G  V+A   +T  G T LH A   G  N+  V  
Sbjct: 109 SKSGLPALHLAAKNKHVDCIPVLVQAGADVNAKGPSTIKGNTALHEAVSVGASNVDSVDA 288

Query: 724 LLQHQADVNAKTKLGYSPLHQAAQQGHTDIV 754
           LL   AD N   + G +    A++ G+ +IV
Sbjct: 289 LLSCGADQNIXNEKGETAYDLASKAGYENIV 381

 Score = 44.3 bits (103), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 32/92 (34%), Positives = 50/92 (54%), Gaps = 5/92 (5%)
 Frame = +1

Query: 46  NQNGLNGLHLASKEGHVKMVVELLHKEIILET---TTKKGNTALHIAALAGQDEV--VRE 100
           +++GL  LHLA+K  HV  +  L+     +     +T KGNTALH A   G   V  V  
Sbjct: 109 SKSGLPALHLAAKNKHVDCIPVLVQAGADVNAKGPSTIKGNTALHEAVSVGASNVDSVDA 288

Query: 101 LVNYGANVNAQSQKGFTPLYMAAQENHLEVVK 132
           L++ GA+ N  ++KG T   +A++  +  +VK
Sbjct: 289 LLSCGADQNIXNEKGETAYDLASKAGYENIVK 384

 Score = 43.1 bits (100), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 29/85 (34%), Positives = 45/85 (52%), Gaps = 5/85 (5%)
 Frame = +1

Query: 605 NGYTPLHIAAKQNQIEVARSLLQYGGSANAE---SVQGVTPLHLAAQEG--HTEMVALLL 659
           +G   LH+AAK   ++    L+Q G   NA+   +++G T LH A   G  + + V  LL
Sbjct: 115 SGLPALHLAAKNKHVDCIPVLVQAGADVNAKGPSTIKGNTALHEAVSVGASNVDSVDALL 294

Query: 660 SKQANGNLGNKSGLTPLHLVSQEGH 684
           S  A+ N+ N+ G T   L S+ G+
Sbjct: 295 SCGADQNIXNEKGETAYDLASKAGY 369

 Score = 42.0 bits (97), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 29/93 (31%), Positives = 48/93 (51%), Gaps = 5/93 (5%)
 Frame = +1

Query: 305 KTKNGLSPIHMAAQGDHLDCVRLLLQYNAEIDD---ITLDHLTPLHVAAHCGHHRVAKV- 360
           ++K+GL  +H+AA+  H+DC+ +L+Q  A+++     T+   T LH A   G   V  V 
Sbjct: 106 ESKSGLPALHLAAKNKHVDCIPVLVQAGADVNAKGPSTIKGNTALHEAVSVGASNVDSVD 285

Query: 361 -LLDKGAKPNSRALNGFTPLHIACKKNHIRVME 392
            LL  GA  N     G T   +A K  +  +++
Sbjct: 286 ALLSCGADQNIXNEKGETAYDLASKAGYENIVK 384

 Score = 37.4 bits (85), Expect = 0.059,   Method: Compositional matrix adjust.
 Identities = 29/87 (33%), Positives = 41/87 (47%), Gaps = 7/87 (8%)
 Frame = +1

Query: 175 KVRLPALHIAARNDDTRTAAVLLQ-----NDPNPDVLSKTGFTPLH--IAAHYENLNVAQ 227
           K  LPALH+AA+N       VL+Q     N   P  +   G T LH  ++    N++   
Sbjct: 112 KSGLPALHLAAKNKHVDCIPVLVQAGADVNAKGPSTI--KGNTALHEAVSVGASNVDSVD 285

Query: 228 LLLNRGASVNFTPQNGITPLHIASRRG 254
            LL+ GA  N   + G T   +AS+ G
Sbjct: 286 ALLSCGADQNIXNEKGETAYDLASKAG 366

 Score = 35.0 bits (79), Expect = 0.31,   Method: Compositional matrix adjust.
 Identities = 29/84 (34%), Positives = 41/84 (48%), Gaps = 5/84 (5%)
 Frame = +1

Query: 537 TKKGFTPLHVAAKYGKVRLAELLLEHDAHPNAAGKN---GLTPLH--VAVHHNNLDIVKL 591
           +K G   LH+AAK   V    +L++  A  NA G +   G T LH  V+V  +N+D V  
Sbjct: 109 SKSGLPALHLAAKNKHVDCIPVLVQAGADVNAKGPSTIKGNTALHEAVSVGASNVDSVDA 288

Query: 592 LLPRGGSPHSPAWNGYTPLHIAAK 615
           LL  G   +     G T   +A+K
Sbjct: 289 LLSCGADQNIXNEKGETAYDLASK 360

 Score = 33.9 bits (76), Expect = 0.55,   Method: Compositional matrix adjust.
 Identities = 24/66 (36%), Positives = 36/66 (54%), Gaps = 3/66 (4%)
 Frame = +1

Query: 394 LLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPNV---SNVKVETPLHMAAR 450
           LL+  AS++  ++SGL  LH+A+   H+  +  L+Q GA  N    S +K  T LH A  
Sbjct: 82  LLRQLASVE--SKSGLPALHLAAKNKHVDCIPVLVQAGADVNAKGPSTIKGNTALHEAVS 255

Query: 451 AGHTEV 456
            G + V
Sbjct: 256 VGASNV 273
>33144
          Length = 272

 Score = 47.4 bits (111), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 30/83 (36%), Positives = 44/83 (53%), Gaps = 1/83 (1%)
 Frame = +3

Query: 607 YTPLHIAAKQNQIEVARSLLQYGGSA-NAESVQGVTPLHLAAQEGHTEMVALLLSKQANG 665
           + PLH+AA   +  +A  L++ G  A N       TPLH A Q     ++ LLL + AN 
Sbjct: 15  WAPLHLAAMNGRTAIAGVLVKKGEVAVNVVDKHKRTPLHYAVQTCELTIIDLLLGRDANP 194

Query: 666 NLGNKSGLTPLHLVSQEGHVPVA 688
           N+ +  G TP HL +Q   +P+A
Sbjct: 195 NIQDVDGNTPTHL-AQMAKLPIA 260

 Score = 47.0 bits (110), Expect = 8e-05,   Method: Compositional matrix adjust.
 Identities = 27/77 (35%), Positives = 41/77 (53%), Gaps = 1/77 (1%)
 Frame = +3

Query: 376 FTPLHIACKKNHIRVMELLLKTG-ASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASP 434
           + PLH+A       +  +L+K G  +++ V +   TPLH A     L I+  LL R A+P
Sbjct: 15  WAPLHLAAMNGRTAIAGVLVKKGEVAVNVVDKHKRTPLHYAVQTCELTIIDLLLGRDANP 194

Query: 435 NVSNVKVETPLHMAARA 451
           N+ +V   TP H+A  A
Sbjct: 195 NIQDVDGNTPTHLAQMA 245

 Score = 46.2 bits (108), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 28/74 (37%), Positives = 42/74 (56%), Gaps = 1/74 (1%)
 Frame = +3

Query: 541 FTPLHVAAKYGKVRLAELLLEH-DAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSP 599
           + PLH+AA  G+  +A +L++  +   N   K+  TPLH AV    L I+ LLL R  +P
Sbjct: 15  WAPLHLAAMNGRTAIAGVLVKKGEVAVNVVDKHKRTPLHYAVQTCELTIIDLLLGRDANP 194

Query: 600 HSPAWNGYTPLHIA 613
           +    +G TP H+A
Sbjct: 195 NIQDVDGNTPTHLA 236

 Score = 43.1 bits (100), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 25/72 (34%), Positives = 36/72 (50%), Gaps = 1/72 (1%)
 Frame = +3

Query: 675 PLHLVSQEGHVPVADVLIKHG-VTVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNA 733
           PLHL +  G   +A VL+K G V V+   +   TPLH A     + ++  LL   A+ N 
Sbjct: 21  PLHLAAMNGRTAIAGVLVKKGEVAVNVVDKHKRTPLHYAVQTCELTIIDLLLGRDANPNI 200

Query: 734 KTKLGYSPLHQA 745
           +   G +P H A
Sbjct: 201 QDVDGNTPTHLA 236

 Score = 42.4 bits (98), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 28/71 (39%), Positives = 38/71 (53%), Gaps = 1/71 (1%)
 Frame = +3

Query: 181 LHIAARNDDTRTAAVLLQN-DPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFT 239
           LH+AA N  T  A VL++  +   +V+ K   TPLH A     L +  LLL R A+ N  
Sbjct: 24  LHLAAMNGRTAIAGVLVKKGEVAVNVVDKHKRTPLHYAVQTCELTIIDLLLGRDANPNIQ 203

Query: 240 PQNGITPLHIA 250
             +G TP H+A
Sbjct: 204 DVDGNTPTHLA 236

 Score = 40.8 bits (94), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 25/75 (33%), Positives = 38/75 (50%), Gaps = 1/75 (1%)
 Frame = +3

Query: 706 YTPLHVASHYGNIKLVKFLLQH-QADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGASP 764
           + PLH+A+  G   +   L++  +  VN   K   +PLH A Q     I+ LLL   A+P
Sbjct: 15  WAPLHLAAMNGRTAIAGVLVKKGEVAVNVVDKHKRTPLHYAVQTCELTIIDLLLGRDANP 194

Query: 765 NEVSSNGTTPLAIAK 779
           N    +G TP  +A+
Sbjct: 195 NIQDVDGNTPTHLAQ 239

 Score = 40.0 bits (92), Expect = 0.009,   Method: Compositional matrix adjust.
 Identities = 25/74 (33%), Positives = 39/74 (52%), Gaps = 1/74 (1%)
 Frame = +3

Query: 211 FTPLHIAAHYENLNVAQLLLNRG-ASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQI 269
           + PLH+AA      +A +L+ +G  +VN   ++  TPLH A +   + ++ LLL R A  
Sbjct: 15  WAPLHLAAMNGRTAIAGVLVKKGEVAVNVVDKHKRTPLHYAVQTCELTIIDLLLGRDANP 194

Query: 270 ETRTKDELTPLHCA 283
             +  D  TP H A
Sbjct: 195 NIQDVDGNTPTHLA 236

 Score = 38.5 bits (88), Expect = 0.026,   Method: Compositional matrix adjust.
 Identities = 25/76 (32%), Positives = 38/76 (50%), Gaps = 1/76 (1%)
 Frame = +3

Query: 275 DELTPLHCAARNGHVRISEILLDHG-APIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYNA 333
           +   PLH AA NG   I+ +L+  G   +    K+  +P+H A Q   L  + LLL  +A
Sbjct: 9   ENWAPLHLAAMNGRTAIAGVLVKKGEVAVNVVDKHKRTPLHYAVQTCELTIIDLLLGRDA 188

Query: 334 EIDDITLDHLTPLHVA 349
             +   +D  TP H+A
Sbjct: 189 NPNIQDVDGNTPTHLA 236

 Score = 37.7 bits (86), Expect = 0.042,   Method: Compositional matrix adjust.
 Identities = 24/72 (33%), Positives = 36/72 (50%), Gaps = 1/72 (1%)
 Frame = +3

Query: 642 PLHLAAQEGHTEMVALLLSK-QANGNLGNKSGLTPLHLVSQEGHVPVADVLIKHGVTVDA 700
           PLHLAA  G T +  +L+ K +   N+ +K   TPLH   Q   + + D+L+      + 
Sbjct: 21  PLHLAAMNGRTAIAGVLVKKGEVAVNVVDKHKRTPLHYAVQTCELTIIDLLLGRDANPNI 200

Query: 701 TTRMGYTPLHVA 712
               G TP H+A
Sbjct: 201 QDVDGNTPTHLA 236

 Score = 35.0 bits (79), Expect = 0.26,   Method: Compositional matrix adjust.
 Identities = 23/72 (31%), Positives = 31/72 (43%), Gaps = 1/72 (1%)
 Frame = +3

Query: 444 PLHMAARAGHTEVXXXXXXXXXXXXXXXXX-XXTPLHCAARIGHTGMVKLLLENGASPNL 502
           PLH+AA  G T +                    TPLH A +     ++ LLL   A+PN+
Sbjct: 21  PLHLAAMNGRTAIAGVLVKKGEVAVNVVDKHKRTPLHYAVQTCELTIIDLLLGRDANPNI 200

Query: 503 ATTAGHTPLHTA 514
               G+TP H A
Sbjct: 201 QDVDGNTPTHLA 236

 Score = 35.0 bits (79), Expect = 0.28,   Method: Compositional matrix adjust.
 Identities = 21/72 (29%), Positives = 37/72 (51%), Gaps = 1/72 (1%)
 Frame = +3

Query: 246 PLHIASRRGNVIMVRLLLDRG-AQIETRTKDELTPLHCAARNGHVRISEILLDHGAPIQA 304
           PLH+A+  G   +  +L+ +G   +    K + TPLH A +   + I ++LL   A    
Sbjct: 21  PLHLAAMNGRTAIAGVLVKKGEVAVNVVDKHKRTPLHYAVQTCELTIIDLLLGRDANPNI 200

Query: 305 KTKNGLSPIHMA 316
           +  +G +P H+A
Sbjct: 201 QDVDGNTPTHLA 236

 Score = 34.3 bits (77), Expect = 0.55,   Method: Compositional matrix adjust.
 Identities = 21/73 (28%), Positives = 36/73 (49%), Gaps = 1/73 (1%)
 Frame = +3

Query: 311 SPIHMAAQGDHLDCVRLLLQYNAEIDDITLDH-LTPLHVAAHCGHHRVAKVLLDKGAKPN 369
           +P+H+AA         +L++      ++   H  TPLH A       +  +LL + A PN
Sbjct: 18  APLHLAAMNGRTAIAGVLVKKGEVAVNVVDKHKRTPLHYAVQTCELTIIDLLLGRDANPN 197

Query: 370 SRALNGFTPLHIA 382
            + ++G TP H+A
Sbjct: 198 IQDVDGNTPTHLA 236

 Score = 33.5 bits (75), Expect = 0.91,   Method: Compositional matrix adjust.
 Identities = 23/72 (31%), Positives = 35/72 (48%), Gaps = 1/72 (1%)
 Frame = +3

Query: 477 PLHCAARIGHTGMVKLLLENG-ASPNLATTAGHTPLHTAAREGHVDTALALLEKEASQAC 535
           PLH AA  G T +  +L++ G  + N+      TPLH A +   +     LL ++A+   
Sbjct: 21  PLHLAAMNGRTAIAGVLVKKGEVAVNVVDKHKRTPLHYAVQTCELTIIDLLLGRDANPNI 200

Query: 536 MTKKGFTPLHVA 547
               G TP H+A
Sbjct: 201 QDVDGNTPTHLA 236
>27108
          Length = 449

 Score = 46.2 bits (108), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 40/130 (30%), Positives = 59/130 (45%), Gaps = 1/130 (0%)
 Frame = -3

Query: 567 NAAGKNGLTPLHVAVHHNNLDIVKLLLPR-GGSPHSPAWNGYTPLHIAAKQNQIEVARSL 625
           N     G T L  A   NNL ++K LL   G   +S  + G+T LH A     +E AR+L
Sbjct: 405 NKKNHKGETMLIRAAIKNNLSLLKHLLTVPGVDINSQDYAGWTALHEACNHGHLECARAL 226

Query: 626 LQYGGSANAESVQGVTPLHLAAQEGHTEMVALLLSKQANGNLGNKSGLTPLHLVSQEGHV 685
           L++  SA  +S           Q G          ++ + +L N+ G+T LH      HV
Sbjct: 225 LKFVPSATLDSF---------FQSGKNRGKV----RKVDMHLANQEGITALHDAVSMNHV 85

Query: 686 PVADVLIKHG 695
            V  +L+K+G
Sbjct: 84  SVVKLLLKYG 55

 Score = 45.8 bits (107), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 40/107 (37%), Positives = 50/107 (46%)
 Frame = -3

Query: 492 LLLENGASPNLATTAGHTPLHTAAREGHVDTALALLEKEASQACMTKKGFTPLHVAAKYG 551
           LL   G   N    AG T LH A   GH++ A ALL+   S    T   F         G
Sbjct: 330 LLTVPGVDINSQDYAGWTALHEACNHGHLECARALLKFVPSA---TLDSF--FQSGKNRG 166

Query: 552 KVRLAELLLEHDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGS 598
           KVR  ++ L        A + G+T LH AV  N++ +VKLLL  GGS
Sbjct: 165 KVRKVDMHL--------ANQEGITALHDAVSMNHVSVVKLLLKYGGS 49

 Score = 40.8 bits (94), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 38/129 (29%), Positives = 56/129 (43%), Gaps = 2/129 (1%)
 Frame = -3

Query: 274 KDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYNA 333
           K E   +  A +N    +  +L   G  I ++   G + +H A    HL+C R LL++  
Sbjct: 390 KGETMLIRAAIKNNLSLLKHLLTVPGVDINSQDYAGWTALHEACNHGHLECARALLKF-- 217

Query: 334 EIDDITLDHLTPLHVAAHCGHHR--VAKVLLDKGAKPNSRALNGFTPLHIACKKNHIRVM 391
            +   TLD           G +R  V KV +    +       G T LH A   NH+ V+
Sbjct: 216 -VPSATLDSFF------QSGKNRGKVRKVDMHLANQE------GITALHDAVSMNHVSVV 76

Query: 392 ELLLKTGAS 400
           +LLLK G S
Sbjct: 75  KLLLKYGGS 49

 Score = 40.8 bits (94), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 29/89 (32%), Positives = 40/89 (44%), Gaps = 20/89 (22%)
 Frame = -3

Query: 365 GAKPNSRALNGFTPLHIACKKNHIRVMELLLKT--GASIDAVTESG-------------- 408
           G   NS+   G+T LH AC   H+     LLK    A++D+  +SG              
Sbjct: 315 GVDINSQDYAGWTALHEACNHGHLECARALLKFVPSATLDSFFQSGKNRGKVRKVDMHLA 136

Query: 409 ----LTPLHVASFMGHLPIVKNLLQRGAS 433
               +T LH A  M H+ +VK LL+ G S
Sbjct: 135 NQEGITALHDAVSMNHVSVVKLLLKYGGS 49

 Score = 40.4 bits (93), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 42/127 (33%), Positives = 59/127 (46%), Gaps = 4/127 (3%)
 Frame = -3

Query: 18  TSFLRAARSGNLDKALDHLRN--GVDINTCNQNGLNGLHLASKEGHVKMVVELLH--KEI 73
           T  +RAA   NL   L HL    GVDIN+ +  G   LH A   GH++    LL      
Sbjct: 381 TMLIRAAIKNNLS-LLKHLLTVPGVDINSQDYAGWTALHEACNHGHLECARALLKFVPSA 205

Query: 74  ILETTTKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKF 133
            L++  + G          G+   VR++  + AN     Q+G T L+ A   NH+ VVK 
Sbjct: 204 TLDSFFQSGKN-------RGK---VRKVDMHLAN-----QEGITALHDAVSMNHVSVVKL 70

Query: 134 LLENGAN 140
           LL+ G +
Sbjct: 69  LLKYGGS 49

 Score = 32.3 bits (72), Expect = 1.9,   Method: Compositional matrix adjust.
 Identities = 21/63 (33%), Positives = 32/63 (50%), Gaps = 1/63 (1%)
 Frame = -3

Query: 698 VDATTRMGYTPLHVASHYGNIKLVKFLLQH-QADVNAKTKLGYSPLHQAAQQGHTDIVTL 756
           V+     G T L  A+   N+ L+K LL     D+N++   G++ LH+A   GH +    
Sbjct: 408 VNKKNHKGETMLIRAAIKNNLSLLKHLLTVPGVDINSQDYAGWTALHEACNHGHLECARA 229

Query: 757 LLK 759
           LLK
Sbjct: 228 LLK 220

 Score = 31.6 bits (70), Expect = 3.0,   Method: Compositional matrix adjust.
 Identities = 28/89 (31%), Positives = 40/89 (44%), Gaps = 22/89 (24%)
 Frame = -3

Query: 201 PNPDVLSK--TGFTPLHIAAHYENLNVAQLLL----------------NRG----ASVNF 238
           P  D+ S+   G+T LH A ++ +L  A+ LL                NRG      ++ 
Sbjct: 318 PGVDINSQDYAGWTALHEACNHGHLECARALLKFVPSATLDSFFQSGKNRGKVRKVDMHL 139

Query: 239 TPQNGITPLHIASRRGNVIMVRLLLDRGA 267
             Q GIT LH A    +V +V+LLL  G 
Sbjct: 138 ANQEGITALHDAVSMNHVSVVKLLLKYGG 52
>27067
          Length = 409

 Score = 46.2 bits (108), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 37/125 (29%), Positives = 60/125 (48%), Gaps = 9/125 (7%)
 Frame = +1

Query: 300 APIQAKTKNGLSPIHMAAQGDHLDCVRLLLQY-NAEIDDITLDHLTPLHVAAHCGHHRVA 358
           A I +K K G S +H A + ++ D +R LL     E + +     TP+  AA  G     
Sbjct: 1   ADINSKFK-GSSAVHEAIKVNNTDILRYLLTVPGLECNAVNASQKTPVMEAASRGRIECL 177

Query: 359 KVLLDKGAKPNSRALNGFTPLH---IACK-----KNHIRVMELLLKTGASIDAVTESGLT 410
            +LLD G       + G T +H   ++C      ++ +  M+L+ K G +I+A    G +
Sbjct: 178 TMLLDHGCNTEGENIRGKTAMHHCLLSCGGFVEIEDMVTCMDLVYKAGGNINAQDWFGTS 357

Query: 411 PLHVA 415
           PLH+A
Sbjct: 358 PLHLA 372

 Score = 37.0 bits (84), Expect = 0.076,   Method: Compositional matrix adjust.
 Identities = 34/130 (26%), Positives = 56/130 (43%), Gaps = 10/130 (7%)
 Frame = +1

Query: 204 DVLSK-TGFTPLHIAAHYENLNVAQLLLNR-GASVNFTPQNGITPLHIASRRGNVIMVRL 261
           D+ SK  G + +H A    N ++ + LL   G   N    +  TP+  A+ RG +  + +
Sbjct: 4   DINSKFKGSSAVHEAIKVNNTDILRYLLTVPGLECNAVNASQKTPVMEAASRGRIECLTM 183

Query: 262 LLDRGAQIETRTKDELTPL-HCAARNG-------HVRISEILLDHGAPIQAKTKNGLSPI 313
           LLD G   E       T + HC    G        V   +++   G  I A+   G SP+
Sbjct: 184 LLDHGCNTEGENIRGKTAMHHCLLSCGGFVEIEDMVTCMDLVYKAGGNINAQDWFGTSPL 363

Query: 314 HMAAQGDHLD 323
           H+A   ++ +
Sbjct: 364 HLAISTENFE 393

 Score = 36.2 bits (82), Expect = 0.12,   Method: Compositional matrix adjust.
 Identities = 29/116 (25%), Positives = 52/116 (44%), Gaps = 9/116 (7%)
 Frame = +1

Query: 243 GITPLHIASRRGNVIMVRLLLDR-GAQIETRTKDELTPLHCAARNGHVRISEILLDHGAP 301
           G + +H A +  N  ++R LL   G +       + TP+  AA  G +    +LLDHG  
Sbjct: 25  GSSAVHEAIKVNNTDILRYLLTVPGLECNAVNASQKTPVMEAASRGRIECLTMLLDHGCN 204

Query: 302 IQAKTKNGLSPIH---MAAQG-----DHLDCVRLLLQYNAEIDDITLDHLTPLHVA 349
            + +   G + +H   ++  G     D + C+ L+ +    I+       +PLH+A
Sbjct: 205 TEGENIRGKTAMHHCLLSCGGFVEIEDMVTCMDLVYKAGGNINAQDWFGTSPLHLA 372

 Score = 35.8 bits (81), Expect = 0.14,   Method: Compositional matrix adjust.
 Identities = 21/87 (24%), Positives = 38/87 (43%), Gaps = 8/87 (9%)
 Frame = +1

Query: 542 TPLHVAAKYGKVRLAELLLEHDAHPNAAGKNGLTPLHVAVH--------HNNLDIVKLLL 593
           TP+  AA  G++    +LL+H  +       G T +H  +          + +  + L+ 
Sbjct: 133 TPVMEAASRGRIECLTMLLDHGCNTEGENIRGKTAMHHCLLSCGGFVEIEDMVTCMDLVY 312

Query: 594 PRGGSPHSPAWNGYTPLHIAAKQNQIE 620
             GG+ ++  W G +PLH+A      E
Sbjct: 313 KAGGNINAQDWFGTSPLHLAISTENFE 393

 Score = 35.0 bits (79), Expect = 0.31,   Method: Compositional matrix adjust.
 Identities = 28/117 (23%), Positives = 54/117 (46%), Gaps = 9/117 (7%)
 Frame = +1

Query: 638 QGVTPLHLAAQEGHTEMVALLLSKQA-NGNLGNKSGLTPLHLVSQEGHVPVADVLIKHGV 696
           +G + +H A +  +T+++  LL+      N  N S  TP+   +  G +    +L+ HG 
Sbjct: 22  KGSSAVHEAIKVNNTDILRYLLTVPGLECNAVNASQKTPVMEAASRGRIECLTMLLDHGC 201

Query: 697 TVDATTRMGYTPLH--VASHYGNIKL------VKFLLQHQADVNAKTKLGYSPLHQA 745
             +     G T +H  + S  G +++      +  + +   ++NA+   G SPLH A
Sbjct: 202 NTEGENIRGKTAMHHCLLSCGGFVEIEDMVTCMDLVYKAGGNINAQDWFGTSPLHLA 372

 Score = 33.5 bits (75), Expect = 0.79,   Method: Compositional matrix adjust.
 Identities = 28/117 (23%), Positives = 47/117 (40%), Gaps = 9/117 (7%)
 Frame = +1

Query: 539 KGFTPLHVAAKYGKVRLAELLLEHDA-HPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGG 597
           KG + +H A K     +   LL       NA   +  TP+  A     ++ + +LL  G 
Sbjct: 22  KGSSAVHEAIKVNNTDILRYLLTVPGLECNAVNASQKTPVMEAASRGRIECLTMLLDHGC 201

Query: 598 SPHSPAWNGYTPLH--------IAAKQNQIEVARSLLQYGGSANAESVQGVTPLHLA 646
           +       G T +H            ++ +     + + GG+ NA+   G +PLHLA
Sbjct: 202 NTEGENIRGKTAMHHCLLSCGGFVEIEDMVTCMDLVYKAGGNINAQDWFGTSPLHLA 372

 Score = 32.3 bits (72), Expect = 1.8,   Method: Compositional matrix adjust.
 Identities = 23/63 (36%), Positives = 35/63 (55%), Gaps = 1/63 (1%)
 Frame = +1

Query: 729 ADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKN-GASPNEVSSNGTTPLAIAKRLGYISVT 787
           AD+N+K K G S +H+A +  +TDI+  LL   G   N V+++  TP+  A   G I   
Sbjct: 1   ADINSKFK-GSSAVHEAIKVNNTDILRYLLTVPGLECNAVNASQKTPVMEAASRGRIECL 177

Query: 788 DVL 790
            +L
Sbjct: 178 TML 186

 Score = 30.4 bits (67), Expect = 6.8,   Method: Compositional matrix adjust.
 Identities = 25/99 (25%), Positives = 44/99 (44%), Gaps = 8/99 (8%)
 Frame = +1

Query: 39  GVDINTCNQNGLNGLHLASKEGHVKMVVELLHKEIILETTTKKGNTALHIAALAGQDEV- 97
           G++ N  N +    +  A+  G ++ +  LL      E    +G TA+H   L+    V 
Sbjct: 97  GLECNAVNASQKTPVMEAASRGRIECLTMLLDHGCNTEGENIRGKTAMHHCLLSCGGFVE 276

Query: 98  VRELVNY-------GANVNAQSQKGFTPLYMAAQENHLE 129
           + ++V         G N+NAQ   G +PL++A    + E
Sbjct: 277 IEDMVTCMDLVYKAGGNINAQDWFGTSPLHLAISTENFE 393
>03590
          Length = 1068

 Score = 39.3 bits (90), Expect(2) = 2e-04,   Method: Compositional matrix adjust.
 Identities = 40/134 (29%), Positives = 62/134 (46%), Gaps = 11/134 (8%)
 Frame = +1

Query: 517 EGHVDTALALLEKEASQACMTKKGFTPLHVAAKYGKVRLAELLLEHDAHPNAAGK----- 571
           E H   AL +L  +    C T    TPL +AA+       +LL E  A+ +A  K     
Sbjct: 370 EKHPGLAL-ILRYKPDLECQTLNSDTPLVLAARSQSADKVKLLAEMGANVDALIKSKLNG 546

Query: 572 NGLTPLHVAVHHNNLDIVKLLLPRGGSPHS-PAWNGYTPLHI-----AAKQNQIEVARSL 625
           N +TP        NL +VKLLL  G  P +  A+   T +H      +A+ + I++ + L
Sbjct: 547 NHVTPCLWMAMQKNLPLVKLLLKYGADPKAVSAYTKETLMHCLVRDRSAEGDVIQLLKLL 726

Query: 626 LQYGGSANAESVQG 639
           ++ G S N+   +G
Sbjct: 727 VEKGLSVNSRDKRG 768

 Score = 25.4 bits (54), Expect(2) = 2e-04,   Method: Compositional matrix adjust.
 Identities = 22/82 (26%), Positives = 33/82 (40%), Gaps = 5/82 (6%)
 Frame = +3

Query: 652 TEMVALLLSKQANGNLGNKSGLTPLHLVS-QEGHVPVADVLIKHGVT----VDATTRMGY 706
           T +   LL  +A+    N  G  P+H V    G  P+  + +         VD     G+
Sbjct: 822 TALEEFLLEHKADVFAKNDDGYMPIHCVFVGCGPDPIELLSLLTAAMKDQQVDEPVLSGF 1001

Query: 707 TPLHVASHYGNIKLVKFLLQHQ 728
           +PLH A+  G       LLQ +
Sbjct: 1002SPLHFAAARGATICCMHLLQRK 1067

 Score = 44.7 bits (104), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 33/92 (35%), Positives = 49/92 (53%), Gaps = 8/92 (8%)
 Frame = +1

Query: 367 KPN--SRALNGFTPLHIACKKNHIRVMELLLKTGASIDAVTESGL-----TPLHVASFMG 419
           KP+   + LN  TPL +A +      ++LL + GA++DA+ +S L     TP    +   
Sbjct: 406 KPDLECQTLNSDTPLVLAARSQSADKVKLLAEMGANVDALIKSKLNGNHVTPCLWMAMQK 585

Query: 420 HLPIVKNLLQRGASPN-VSNVKVETPLHMAAR 450
           +LP+VK LL+ GA P  VS    ET +H   R
Sbjct: 586 NLPLVKLLLKYGADPKAVSAYTKETLMHCLVR 681

 Score = 43.5 bits (101), Expect = 8e-04,   Method: Compositional matrix adjust.
 Identities = 33/129 (25%), Positives = 67/129 (51%), Gaps = 13/129 (10%)
 Frame = +1

Query: 194 AVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFTPQ-----NGITPLH 248
           A++L+  P+ +  +    TPL +AA  ++ +  +LL   GA+V+   +     N +TP  
Sbjct: 388 ALILRYKPDLECQTLNSDTPLVLAARSQSADKVKLLAEMGANVDALIKSKLNGNHVTPCL 567

Query: 249 IASRRGNVIMVRLLLDRGAQ---IETRTKDELTPLHCAARNGH-----VRISEILLDHGA 300
             + + N+ +V+LLL  GA    +   TK+ L  +HC  R+       +++ ++L++ G 
Sbjct: 568 WMAMQKNLPLVKLLLKYGADPKAVSAYTKETL--MHCLVRDRSAEGDVIQLLKLLVEKGL 741

Query: 301 PIQAKTKNG 309
            + ++ K G
Sbjct: 742 SVNSRDKRG 768

 Score = 38.5 bits (88), Expect = 0.027,   Method: Compositional matrix adjust.
 Identities = 35/125 (28%), Positives = 63/125 (50%), Gaps = 11/125 (8%)
 Frame = +1

Query: 625 LLQYGGSANAESVQGVTPLHLAAQEGHTEMVALLLSKQANGNLGNKSGL-----TPLHLV 679
           +L+Y      +++   TPL LAA+    + V LL    AN +   KS L     TP   +
Sbjct: 394 ILRYKPDLECQTLNSDTPLVLAARSQSADKVKLLAEMGANVDALIKSKLNGNHVTPCLWM 573

Query: 680 SQEGHVPVADVLIKHGV---TVDATTR--MGYTPLHVASHYGN-IKLVKFLLQHQADVNA 733
           + + ++P+  +L+K+G     V A T+  + +  +   S  G+ I+L+K L++    VN+
Sbjct: 574 AMQKNLPLVKLLLKYGADPKAVSAYTKETLMHCLVRDRSAEGDVIQLLKLLVEKGLSVNS 753

Query: 734 KTKLG 738
           + K G
Sbjct: 754 RDKRG 768

 Score = 37.7 bits (86), Expect = 0.040,   Method: Compositional matrix adjust.
 Identities = 24/70 (34%), Positives = 33/70 (47%), Gaps = 5/70 (7%)
 Frame = +3

Query: 286 NGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYNA-----EIDDITL 340
           N    + E LL+H A + AK  +G  PIH    G   D + LL    A     ++D+  L
Sbjct: 813 NDSTALEEFLLEHKADVFAKNDDGYMPIHCVFVGCGPDPIELLSLLTAAMKDQQVDEPVL 992

Query: 341 DHLTPLHVAA 350
              +PLH AA
Sbjct: 993 SGFSPLHFAA 1022

 Score = 37.7 bits (86), Expect = 0.049,   Method: Compositional matrix adjust.
 Identities = 37/126 (29%), Positives = 59/126 (46%), Gaps = 11/126 (8%)
 Frame = +1

Query: 261 LLLDRGAQIETRTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTK-----NGLSPIHM 315
           L+L     +E +T +  TPL  AAR+      ++L + GA + A  K     N ++P   
Sbjct: 391 LILRYKPDLECQTLNSDTPLVLAARSQSADKVKLLAEMGANVDALIKSKLNGNHVTPCLW 570

Query: 316 AAQGDHLDCVRLLLQYNAEIDDI------TLDHLTPLHVAAHCGHHRVAKVLLDKGAKPN 369
            A   +L  V+LLL+Y A+   +      TL H      +A     ++ K+L++KG   N
Sbjct: 571 MAMQKNLPLVKLLLKYGADPKAVSAYTKETLMHCLVRDRSAEGDVIQLLKLLVEKGLSVN 750

Query: 370 SRALNG 375
           SR   G
Sbjct: 751 SRDKRG 768

 Score = 36.6 bits (83), Expect = 0.097,   Method: Compositional matrix adjust.
 Identities = 24/78 (30%), Positives = 33/78 (42%), Gaps = 5/78 (6%)
 Frame = +3

Query: 555 LAELLLEHDAHPNAAGKNGLTPLHVAVHHNNLDIVKLL-----LPRGGSPHSPAWNGYTP 609
           L E LLEH A   A   +G  P+H        D ++LL       +      P  +G++P
Sbjct: 828 LEEFLLEHKADVFAKNDDGYMPIHCVFVGCGPDPIELLSLLTAAMKDQQVDEPVLSGFSP 1007

Query: 610 LHIAAKQNQIEVARSLLQ 627
           LH AA +        LLQ
Sbjct: 1008LHFAAARGATICCMHLLQ 1061

 Score = 34.7 bits (78), Expect = 0.38,   Method: Compositional matrix adjust.
 Identities = 41/186 (22%), Positives = 69/186 (37%), Gaps = 17/186 (9%)
 Frame = +1

Query: 75  LETTTKKGNTALHIAALAGQDEVVRE------------LVNYGANVNAQSQKGFTPLYMA 122
           L  T +   TA H+ A    +  V+E            ++ Y  ++  Q+    TPL +A
Sbjct: 280 LSYTAEGKYTATHLMASCQTEMPVKEGGVEEKHPGLALILRYKPDLECQTLNSDTPLVLA 459

Query: 123 AQENHLEVVKFLLENGANQNVATEDGF-----TPLAVALQQGHENVVAHLINYGTKGKVR 177
           A+    + VK L E GAN +   +        TP      Q +  +V  L+ YG   K  
Sbjct: 460 ARSQSADKVKLLAEMGANVDALIKSKLNGNHVTPCLWMAMQKNLPLVKLLLKYGADPKA- 636

Query: 178 LPALHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVN 237
                ++A   +T    ++       DV                 + + +LL+ +G SVN
Sbjct: 637 -----VSAYTKETLMHCLVRDRSAEGDV-----------------IQLLKLLVEKGLSVN 750

Query: 238 FTPQNG 243
              + G
Sbjct: 751 SRDKRG 768

 Score = 34.3 bits (77), Expect = 0.45,   Method: Compositional matrix adjust.
 Identities = 22/77 (28%), Positives = 37/77 (48%), Gaps = 5/77 (6%)
 Frame = +3

Query: 359 KVLLDKGAKPNSRALNGFTPLH---IACKKNHIRVMELLLKT--GASIDAVTESGLTPLH 413
           + LL+  A   ++  +G+ P+H   + C  + I ++ LL        +D    SG +PLH
Sbjct: 834 EFLLEHKADVFAKNDDGYMPIHCVFVGCGPDPIELLSLLTAAMKDQQVDEPVLSGFSPLH 1013

Query: 414 VASFMGHLPIVKNLLQR 430
            A+  G      +LLQR
Sbjct: 1014FAAARGATICCMHLLQR 1064

 Score = 33.1 bits (74), Expect = 0.97,   Method: Compositional matrix adjust.
 Identities = 14/24 (58%), Positives = 18/24 (75%)
 Frame = +3

Query: 720 LVKFLLQHQADVNAKTKLGYSPLH 743
           L +FLL+H+ADV AK   GY P+H
Sbjct: 828 LEEFLLEHKADVFAKNDDGYMPIH 899

 Score = 33.1 bits (74), Expect = 0.99,   Method: Compositional matrix adjust.
 Identities = 25/76 (32%), Positives = 35/76 (46%), Gaps = 5/76 (6%)
 Frame = +3

Query: 689 DVLIKHGVTVDATTRMGYTPLH---VASHYGNIKLVKFLLQHQAD--VNAKTKLGYSPLH 743
           + L++H   V A    GY P+H   V      I+L+  L     D  V+     G+SPLH
Sbjct: 834 EFLLEHKADVFAKNDDGYMPIHCVFVGCGPDPIELLSLLTAAMKDQQVDEPVLSGFSPLH 1013

Query: 744 QAAQQGHTDIVTLLLK 759
            AA +G T     LL+
Sbjct: 1014FAAARGATICCMHLLQ 1061
>21751
          Length = 643

 Score = 45.1 bits (105), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 31/96 (32%), Positives = 49/96 (51%), Gaps = 9/96 (9%)
 Frame = +3

Query: 688 ADVLIKHG--------VTVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGY 739
           +++LI++G        V++D       +PLHVA    N+ L + LL+H  DVN       
Sbjct: 3   SNLLIQYGADVHQLRTVSLDDKVFTSQSPLHVAILRKNVHLGRLLLEHGEDVNQTFNDSL 182

Query: 740 -SPLHQAAQQGHTDIVTLLLKNGASPNEVSSNGTTP 774
            SP+HQA +    D++ LL++ GA  N  +   T P
Sbjct: 183 ESPIHQAVRNLDLDMINLLIEFGADLNRPNF*TTYP 290

 Score = 42.7 bits (99), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 30/89 (33%), Positives = 46/89 (51%), Gaps = 12/89 (13%)
 Frame = +3

Query: 226 AQLLLNRGASVN-----------FTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETRTK 274
           + LL+  GA V+           FT Q   +PLH+A  R NV + RLLL+ G  +     
Sbjct: 3   SNLLIQYGADVHQLRTVSLDDKVFTSQ---SPLHVAILRKNVHLGRLLLEHGEDVNQTFN 173

Query: 275 DEL-TPLHCAARNGHVRISEILLDHGAPI 302
           D L +P+H A RN  + +  +L++ GA +
Sbjct: 174 DSLESPIHQAVRNLDLDMINLLIEFGADL 260

 Score = 42.4 bits (98), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 29/85 (34%), Positives = 41/85 (48%), Gaps = 4/85 (4%)
 Frame = +3

Query: 534 ACMTKKGFT---PLHVAAKYGKVRLAELLLEHDAHPNAAGKNGL-TPLHVAVHHNNLDIV 589
             +  K FT   PLHVA     V L  LLLEH    N    + L +P+H AV + +LD++
Sbjct: 51  VSLDDKVFTSQSPLHVAILRKNVHLGRLLLEHGEDVNQTFNDSLESPIHQAVRNLDLDMI 230

Query: 590 KLLLPRGGSPHSPAWNGYTPLHIAA 614
            LL+  G   + P +    P  + A
Sbjct: 231 NLLIEFGADLNRPNF*TTYPGRVVA 305

 Score = 40.0 bits (92), Expect = 0.010,   Method: Compositional matrix adjust.
 Identities = 22/62 (35%), Positives = 39/62 (62%), Gaps = 1/62 (1%)
 Frame = +3

Query: 209 TGFTPLHIAAHYENLNVAQLLLNRGASVNFTPQNGI-TPLHIASRRGNVIMVRLLLDRGA 267
           T  +PLH+A   +N+++ +LLL  G  VN T  + + +P+H A R  ++ M+ LL++ GA
Sbjct: 75  TSQSPLHVAILRKNVHLGRLLLEHGEDVNQTFNDSLESPIHQAVRNLDLDMINLLIEFGA 254

Query: 268 QI 269
            +
Sbjct: 255 DL 260

 Score = 33.5 bits (75), Expect = 0.87,   Method: Composition-based stats.
 Identities = 16/45 (35%), Positives = 26/45 (57%), Gaps = 5/45 (11%)
 Frame = +1

Query: 687 VADVLIKHGVTVDATTRMG-----YTPLHVASHYGNIKLVKFLLQ 726
           +A  LI  G + +  TR+      Y+PLH+A   GN+  V+FL++
Sbjct: 334 IAKRLIVAGASANQRTRISFFQKTYSPLHIACFKGNLGFVRFLVE 468

 Score = 31.2 bits (69), Expect = 4.2,   Method: Compositional matrix adjust.
 Identities = 21/77 (27%), Positives = 37/77 (48%), Gaps = 1/77 (1%)
 Frame = +3

Query: 377 TPLHIACKKNHIRVMELLLKTGASIDAVTESGL-TPLHVASFMGHLPIVKNLLQRGASPN 435
           +PLH+A  + ++ +  LLL+ G  ++      L +P+H A     L ++  L++ GA  N
Sbjct: 84  SPLHVAILRKNVHLGRLLLEHGEDVNQTFNDSLESPIHQAVRNLDLDMINLLIEFGADLN 263

Query: 436 VSNVKVETPLHMAARAG 452
             N     P  + A  G
Sbjct: 264 RPNF*TTYPGRVVADHG 314
>30978
          Length = 566

 Score = 42.4 bits (98), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 26/70 (37%), Positives = 36/70 (51%), Gaps = 1/70 (1%)
 Frame = -2

Query: 631 SANAESVQGVTPLHLAAQEGHTEMVALLLSK-QANGNLGNKSGLTPLHLVSQEGHVPVAD 689
           S N     G TPLH A   GH + + +LLS+ +   N+ NK G T LH  + + HV    
Sbjct: 496 SVNGLDKAGSTPLHWAGHGGHMDCLQVLLSEPKCEVNVQNKLGDTALHSAAWKNHVEAVK 317

Query: 690 VLIKHGVTVD 699
           +L+  G  VD
Sbjct: 316 MLLGKGARVD 287

 Score = 41.6 bits (96), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 29/91 (31%), Positives = 45/91 (49%), Gaps = 1/91 (1%)
 Frame = -2

Query: 282 CAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLL-QYNAEIDDITL 340
           C     H  ++E L +    +    K G +P+H A  G H+DC+++LL +   E++    
Sbjct: 550 CCKTRQH*FLTECLSNR-VSVNGLDKAGSTPLHWAGHGGHMDCLQVLLSEPKCEVNVQNK 374

Query: 341 DHLTPLHVAAHCGHHRVAKVLLDKGAKPNSR 371
              T LH AA   H    K+LL KGA+ + R
Sbjct: 373 LGDTALHSAAWKNHVEAVKMLLGKGARVDLR 281

 Score = 38.9 bits (89), Expect = 0.020,   Method: Compositional matrix adjust.
 Identities = 25/78 (32%), Positives = 40/78 (51%), Gaps = 1/78 (1%)
 Frame = -2

Query: 659 LSKQANGNLGNKSGLTPLHLVSQEGHVPVADVLIKH-GVTVDATTRMGYTPLHVASHYGN 717
           LS + + N  +K+G TPLH     GH+    VL+      V+   ++G T LH A+   +
Sbjct: 511 LSNRVSVNGLDKAGSTPLHWAGHGGHMDCLQVLLSEPKCEVNVQNKLGDTALHSAAWKNH 332

Query: 718 IKLVKFLLQHQADVNAKT 735
           ++ VK LL   A V+ + 
Sbjct: 331 VEAVKMLLGKGARVDLRN 278

 Score = 38.1 bits (87), Expect = 0.035,   Method: Compositional matrix adjust.
 Identities = 27/79 (34%), Positives = 41/79 (51%), Gaps = 1/79 (1%)
 Frame = -2

Query: 225 VAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDR-GAQIETRTKDELTPLHCA 283
           + + L NR  SVN   + G TPLH A   G++  +++LL     ++  + K   T LH A
Sbjct: 523 LTECLSNR-VSVNGLDKAGSTPLHWAGHGGHMDCLQVLLSEPKCEVNVQNKLGDTALHSA 347

Query: 284 ARNGHVRISEILLDHGAPI 302
           A   HV   ++LL  GA +
Sbjct: 346 AWKNHVEAVKMLLGKGARV 290

 Score = 36.6 bits (83), Expect = 0.094,   Method: Compositional matrix adjust.
 Identities = 27/68 (39%), Positives = 31/68 (45%), Gaps = 1/68 (1%)
 Frame = -2

Query: 494 LENGASPNLATTAGHTPLHTAAREGHVDTALALL-EKEASQACMTKKGFTPLHVAAKYGK 552
           L N  S N    AG TPLH A   GH+D    LL E +       K G T LH AA    
Sbjct: 511 LSNRVSVNGLDKAGSTPLHWAGHGGHMDCLQVLLSEPKCEVNVQNKLGDTALHSAAWKNH 332

Query: 553 VRLAELLL 560
           V   ++LL
Sbjct: 331 VEAVKMLL 308

 Score = 36.6 bits (83), Expect = 0.10,   Method: Compositional matrix adjust.
 Identities = 24/75 (32%), Positives = 34/75 (45%), Gaps = 1/75 (1%)
 Frame = -2

Query: 382 ACKKNHIRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQR-GASPNVSNVK 440
            CK      +   L    S++ + ++G TPLH A   GH+  ++ LL       NV N  
Sbjct: 550 CCKTRQH*FLTECLSNRVSVNGLDKAGSTPLHWAGHGGHMDCLQVLLSEPKCEVNVQNKL 371

Query: 441 VETPLHMAARAGHTE 455
            +T LH AA   H E
Sbjct: 370 GDTALHSAAWKNHVE 326

 Score = 35.8 bits (81), Expect = 0.15,   Method: Compositional matrix adjust.
 Identities = 23/57 (40%), Positives = 30/57 (52%), Gaps = 1/57 (1%)
 Frame = -2

Query: 476 TPLHCAARIGHTGMVKLLL-ENGASPNLATTAGHTPLHTAAREGHVDTALALLEKEA 531
           TPLH A   GH   +++LL E     N+    G T LH+AA + HV+    LL K A
Sbjct: 466 TPLHWAGHGGHMDCLQVLLSEPKCEVNVQNKLGDTALHSAAWKNHVEAVKMLLGKGA 296

 Score = 30.8 bits (68), Expect = 4.8,   Method: Compositional matrix adjust.
 Identities = 14/34 (41%), Positives = 19/34 (55%)
 Frame = -2

Query: 725 LQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLL 758
           L ++  VN   K G +PLH A   GH D + +LL
Sbjct: 511 LSNRVSVNGLDKAGSTPLHWAGHGGHMDCLQVLL 410
>17893
          Length = 453

 Score = 40.8 bits (94), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 25/58 (43%), Positives = 29/58 (50%)
 Frame = -3

Query: 489 MVKLLLENGASPNLATTAGHTPLHTAAREGHVDTALALLEKEASQACMTKKGFTPLHV 546
            V  LL+NGAS N+    G T LH AAR  HVD    LL+   +       G T LHV
Sbjct: 175 FVDSLLKNGASINIMDRTGQTLLHEAARAWHVDVTRWLLDHGINIDQPDYYGRTALHV 2

 Score = 40.0 bits (92), Expect = 0.009,   Method: Compositional matrix adjust.
 Identities = 24/61 (39%), Positives = 31/61 (50%)
 Frame = -3

Query: 222 NLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETRTKDELTPLH 281
           NL+    LL  GAS+N   + G T LH A+R  +V + R LLD G  I+       T LH
Sbjct: 184 NLDFVDSLLKNGASINIMDRTGQTLLHEAARAWHVDVTRWLLDHGINIDQPDYYGRTALH 5

Query: 282 C 282
            
Sbjct: 4   V 2

 Score = 39.7 bits (91), Expect = 0.012,   Method: Compositional matrix adjust.
 Identities = 21/59 (35%), Positives = 32/59 (54%)
 Frame = -3

Query: 653 EMVALLLSKQANGNLGNKSGLTPLHLVSQEGHVPVADVLIKHGVTVDATTRMGYTPLHV 711
           + V  LL   A+ N+ +++G T LH  ++  HV V   L+ HG+ +D     G T LHV
Sbjct: 178 DFVDSLLKNGASINIMDRTGQTLLHEAARAWHVDVTRWLLDHGINIDQPDYYGRTALHV 2

 Score = 38.1 bits (87), Expect = 0.032,   Method: Compositional matrix adjust.
 Identities = 23/61 (37%), Positives = 30/61 (49%)
 Frame = -3

Query: 255 NVIMVRLLLDRGAQIETRTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIH 314
           N+  V  LL  GA I    +   T LH AAR  HV ++  LLDHG  I      G + +H
Sbjct: 184 NLDFVDSLLKNGASINIMDRTGQTLLHEAARAWHVDVTRWLLDHGINIDQPDYYGRTALH 5

Query: 315 M 315
           +
Sbjct: 4   V 2

 Score = 38.1 bits (87), Expect = 0.036,   Method: Compositional matrix adjust.
 Identities = 19/61 (31%), Positives = 33/61 (54%)
 Frame = -3

Query: 717 NIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGASPNEVSSNGTTPLA 776
           N+  V  LL++ A +N   + G + LH+AA+  H D+   LL +G + ++    G T L 
Sbjct: 184 NLDFVDSLLKNGASINIMDRTGQTLLHEAARAWHVDVTRWLLDHGINIDQPDYYGRTALH 5

Query: 777 I 777
           +
Sbjct: 4   V 2

 Score = 36.6 bits (83), Expect = 0.10,   Method: Compositional matrix adjust.
 Identities = 22/61 (36%), Positives = 31/61 (50%)
 Frame = -3

Query: 28  NLDKALDHLRNGVDINTCNQNGLNGLHLASKEGHVKMVVELLHKEIILETTTKKGNTALH 87
           NLD     L+NG  IN  ++ G   LH A++  HV +   LL   I ++     G TALH
Sbjct: 184 NLDFVDSLLKNGASINIMDRTGQTLLHEAARAWHVDVTRWLLDHGINIDQPDYYGRTALH 5

Query: 88  I 88
           +
Sbjct: 4   V 2

 Score = 34.3 bits (77), Expect = 0.53,   Method: Compositional matrix adjust.
 Identities = 20/63 (31%), Positives = 35/63 (55%)
 Frame = -3

Query: 385 KNHIRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETP 444
           K ++  ++ LLK GASI+ +  +G T LH A+   H+ + + LL  G + +  +    T 
Sbjct: 190 KINLDFVDSLLKNGASINIMDRTGQTLLHEAARAWHVDVTRWLLDHGINIDQPDYYGRTA 11

Query: 445 LHM 447
           LH+
Sbjct: 10  LHV 2

 Score = 33.5 bits (75), Expect = 0.79,   Method: Compositional matrix adjust.
 Identities = 20/54 (37%), Positives = 27/54 (50%)
 Frame = -3

Query: 295 LLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYNAEIDDITLDHLTPLHV 348
           LL +GA I    + G + +H AA+  H+D  R LL +   ID       T LHV
Sbjct: 163 LLKNGASINIMDRTGQTLLHEAARAWHVDVTRWLLDHGINIDQPDYYGRTALHV 2

 Score = 33.5 bits (75), Expect = 0.83,   Method: Compositional matrix adjust.
 Identities = 17/36 (47%), Positives = 23/36 (63%)
 Frame = -3

Query: 421 LPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEV 456
           L  V +LL+ GAS N+ +   +T LH AARA H +V
Sbjct: 181 LDFVDSLLKNGASINIMDRTGQTLLHEAARAWHVDV 74

 Score = 33.1 bits (74), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 21/60 (35%), Positives = 30/60 (50%)
 Frame = -3

Query: 520 VDTALALLEKEASQACMTKKGFTPLHVAAKYGKVRLAELLLEHDAHPNAAGKNGLTPLHV 579
           +D   +LL+  AS   M + G T LH AA+   V +   LL+H  + +     G T LHV
Sbjct: 181 LDFVDSLLKNGASINIMDRTGQTLLHEAARAWHVDVTRWLLDHGINIDQPDYYGRTALHV 2

 Score = 30.4 bits (67), Expect = 7.1,   Method: Compositional matrix adjust.
 Identities = 25/64 (39%), Positives = 32/64 (50%)
 Frame = -3

Query: 724 LLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGASPNEVSSNGTTPLAIAKRLGY 783
           L+QH  D      +  SP H+ A+    D V  LLKNGAS N +   G T L  A R  +
Sbjct: 238 LIQHFVD------MADSP-HEEAKIN-LDFVDSLLKNGASINIMDRTGQTLLHEAARAWH 83

Query: 784 ISVT 787
           + VT
Sbjct: 82  VDVT 71

 Score = 30.0 bits (66), Expect = 9.8,   Method: Compositional matrix adjust.
 Identities = 22/60 (36%), Positives = 28/60 (46%)
 Frame = -3

Query: 322 LDCVRLLLQYNAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHI 381
           LD V  LL+  A I+ +     T LH AA   H  V + LLD G   +     G T LH+
Sbjct: 181 LDFVDSLLKNGASINIMDRTGQTLLHEAARAWHVDVTRWLLDHGINIDQPDYYGRTALHV 2
>25464
          Length = 440

 Score = 40.4 bits (93), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 30/93 (32%), Positives = 48/93 (51%), Gaps = 6/93 (6%)
 Frame = -3

Query: 704 MGYTPLHVASHYGNIKLVKFLLQHQA-DVNAKTKLGYSPLHQAAQQGHTDIVTLL----L 758
           MG T L  A   G   +V+ +L+    D+N     G +P+H AA   + +IV +L     
Sbjct: 414 MGRTALSYACLNGRQDIVRCILKEDVLDINEPDNDGNTPIHHAAISANPNIVRMLAEAFY 235

Query: 759 KNGASPNEVSSNGTTPLAIAKRLG-YISVTDVL 790
           K G +P++ +  G TPL +A + G Y+S   +L
Sbjct: 234 KFGLNPDKRNKLGYTPLLLACKGGNYVSAYTLL 136

 Score = 39.7 bits (91), Expect = 0.012,   Method: Compositional matrix adjust.
 Identities = 31/107 (28%), Positives = 52/107 (48%), Gaps = 6/107 (5%)
 Frame = -3

Query: 300 APIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYNA-EIDDITLDHLTPLHVAAHCGHHRVA 358
           A +  +   G + +  A      D VR +L+ +  +I++   D  TP+H AA   +  + 
Sbjct: 438 AYLNVRDSMGRTALSYACLNGRQDIVRCILKEDVLDINEPDNDGNTPIHHAAISANPNIV 259

Query: 359 KVLLDK----GAKPNSRALNGFTPLHIACK-KNHIRVMELLLKTGAS 400
           ++L +     G  P+ R   G+TPL +ACK  N++    LL  T AS
Sbjct: 258 RMLAEAFYKFGLNPDKRNKLGYTPLLLACKGGNYVSAYTLLTTTKAS 118

 Score = 35.4 bits (80), Expect = 0.21,   Method: Compositional matrix adjust.
 Identities = 25/90 (27%), Positives = 40/90 (44%), Gaps = 5/90 (5%)
 Frame = -3

Query: 633 NAESVQGVTPLHLAAQEGHTEMVALLLSKQA-NGNLGNKSGLTPLHLVSQEGHVPV---- 687
           N     G T L  A   G  ++V  +L +   + N  +  G TP+H  +   +  +    
Sbjct: 429 NVRDSMGRTALSYACLNGRQDIVRCILKEDVLDINEPDNDGNTPIHHAAISANPNIVRML 250

Query: 688 ADVLIKHGVTVDATTRMGYTPLHVASHYGN 717
           A+   K G+  D   ++GYTPL +A   GN
Sbjct: 249 AEAFYKFGLNPDKRNKLGYTPLLLACKGGN 160
>13900
          Length = 751

 Score = 40.4 bits (93), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 30/98 (30%), Positives = 49/98 (50%), Gaps = 1/98 (1%)
 Frame = +1

Query: 571 KNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQIEVARSLLQYGG 630
           ++G +PLH+AV  N+    K LL  G  P  P ++G TPL + A+ ++       + Y  
Sbjct: 274 RSGQSPLHLAVRVNDFHKAKKLLKLGSDPLLPDFSGITPLRM-AQGHEYNAIVFYMCYVR 450

Query: 631 SANAE-SVQGVTPLHLAAQEGHTEMVALLLSKQANGNL 667
             N    V+G T L  A ++ +   + +LL   AN +L
Sbjct: 451 DINVNVMVRGETTLQQAVRDNYLLGIQVLLRSGANPDL 564

 Score = 40.0 bits (92), Expect = 0.009,   Method: Compositional matrix adjust.
 Identities = 33/131 (25%), Positives = 62/131 (47%), Gaps = 4/131 (3%)
 Frame = +1

Query: 208 KTGFTPLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIA-SRRGNVIMVRLLLDRG 266
           ++G +PLH+A    + + A+ LL  G+       +GITPL +A     N I+  +   R 
Sbjct: 274 RSGQSPLHLAVRVNDFHKAKKLLKLGSDPLLPDFSGITPLRMAQGHEYNAIVFYMCYVRD 453

Query: 267 AQIETRTKDELTPLHCAARNGHVRISEILLDHGAP---IQAKTKNGLSPIHMAAQGDHLD 323
             +    + E T L  A R+ ++   ++LL  GA    +      G + + +A    +++
Sbjct: 454 INVNVMVRGE-TTLQQAVRDNYLLGIQVLLRSGANPDLVVRMPSYGQNCLELAVMCRYVN 630

Query: 324 CVRLLLQYNAE 334
            VR L+ +N +
Sbjct: 631 AVRALIVHNCK 663

 Score = 38.9 bits (89), Expect = 0.018,   Method: Compositional matrix adjust.
 Identities = 37/133 (27%), Positives = 62/133 (46%), Gaps = 10/133 (7%)
 Frame = +1

Query: 108 VNAQS-QKGFTPLYMAAQENHLEVVKFLLENGANQNVATEDGFTPLAVALQQGHE-NVVA 165
           +N Q  + G +PL++A + N     K LL+ G++  +    G TPL +A  QGHE N + 
Sbjct: 256 LNCQDPRSGQSPLHLAVRVNDFHKAKKLLKLGSDPLLPDFSGITPLRMA--QGHEYNAIV 429

Query: 166 HLINYGTKGKVRL-----PALHIAARNDDTRTAAVLLQNDPNPDVLSKT---GFTPLHIA 217
             + Y     V +       L  A R++      VLL++  NPD++ +    G   L +A
Sbjct: 430 FYMCYVRDINVNVMVRGETTLQQAVRDNYLLGIQVLLRSGANPDLVVRMPSYGQNCLELA 609

Query: 218 AHYENLNVAQLLL 230
                +N  + L+
Sbjct: 610 VMCRYVNAVRALI 648

 Score = 33.5 bits (75), Expect = 0.77,   Method: Compositional matrix adjust.
 Identities = 35/130 (26%), Positives = 58/130 (44%), Gaps = 6/130 (4%)
 Frame = +1

Query: 476 TPLHCAARIGHTGMVKLLLENGASPNLATTAGHTPLHTAAREGHVDTALALLE---KEAS 532
           +PLH A R+      K LL+ G+ P L   +G TPL  A  +GH   A+       ++ +
Sbjct: 286 SPLHLAVRVNDFHKAKKLLKLGSDPLLPDFSGITPLRMA--QGHEYNAIVFYMCYVRDIN 459

Query: 533 QACMTKKGFTPLHVAAKYGKVRLAELLLEHDAHPNAAGK---NGLTPLHVAVHHNNLDIV 589
              M  +G T L  A +   +   ++LL   A+P+   +    G   L +AV    ++ V
Sbjct: 460 VNVMV-RGETTLQQAVRDNYLLGIQVLLRSGANPDLVVRMPSYGQNCLELAVMCRYVNAV 636

Query: 590 KLLLPRGGSP 599
           + L+     P
Sbjct: 637 RALIVHNCKP 666

 Score = 32.0 bits (71), Expect = 2.4,   Method: Compositional matrix adjust.
 Identities = 34/127 (26%), Positives = 55/127 (43%), Gaps = 6/127 (4%)
 Frame = +1

Query: 506 AGHTPLHTAAREGHVDTALALLEKEASQACMTKKGFTPLHVAA--KYGKVRLAELLLEHD 563
           +G +PLH A R      A  LL+  +        G TPL +A   +Y  + +  +    D
Sbjct: 277 SGQSPLHLAVRVNDFHKAKKLLKLGSDPLLPDFSGITPLRMAQGHEYNAI-VFYMCYVRD 453

Query: 564 AHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSP----HSPAWNGYTPLHIAAKQNQI 619
            + N   + G T L  AV  N L  +++LL  G +P      P++ G   L +A     +
Sbjct: 454 INVNVMVR-GETTLQQAVRDNYLLGIQVLLRSGANPDLVVRMPSY-GQNCLELAVMCRYV 627

Query: 620 EVARSLL 626
              R+L+
Sbjct: 628 NAVRALI 648

 Score = 30.8 bits (68), Expect = 5.6,   Method: Compositional matrix adjust.
 Identities = 26/93 (27%), Positives = 42/93 (45%)
 Frame = +1

Query: 344 TPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHIRVMELLLKTGASIDA 403
           +PLH+A        AK LL  G+ P     +G TPL +A    +  ++  +         
Sbjct: 286 SPLHLAVRVNDFHKAKKLLKLGSDPLLPDFSGITPLRMAQGHEYNAIVFYMCYVRDINVN 465

Query: 404 VTESGLTPLHVASFMGHLPIVKNLLQRGASPNV 436
           V   G T L  A    +L  ++ LL+ GA+P++
Sbjct: 466 VMVRGETTLQQAVRDNYLLGIQVLLRSGANPDL 564

 Score = 30.0 bits (66), Expect = 9.6,   Method: Compositional matrix adjust.
 Identities = 27/78 (34%), Positives = 39/78 (50%), Gaps = 1/78 (1%)
 Frame = +1

Query: 374 NGFTPLHIACKKNHIRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQ-RGA 432
           +G +PLH+A + N     + LLK G+       SG+TPL +A    +  IV  +   R  
Sbjct: 277 SGQSPLHLAVRVNDFHKAKKLLKLGSDPLLPDFSGITPLRMAQGHEYNAIVFYMCYVRDI 456

Query: 433 SPNVSNVKVETPLHMAAR 450
           + NV  V+ ET L  A R
Sbjct: 457 NVNVM-VRGETTLQQAVR 507
>30217
          Length = 412

 Score = 39.3 bits (90), Expect = 0.015,   Method: Compositional matrix adjust.
 Identities = 21/66 (31%), Positives = 35/66 (53%), Gaps = 3/66 (4%)
 Frame = -3

Query: 374 NGFTPLHIACKKNHIRVMELLLKTG---ASIDAVTESGLTPLHVASFMGHLPIVKNLLQR 430
           +G TPLH+AC   ++ V+  L++       ++   +   TPLH+A+      I++ LL  
Sbjct: 209 DGDTPLHLACISGYVDVVAALIRMAPHPCLLNIQNDVAQTPLHLAALTAQPTILRMLLLA 30

Query: 431 GASPNV 436
           GA P V
Sbjct: 29  GAEPTV 12

 Score = 37.4 bits (85), Expect = 0.059,   Method: Compositional matrix adjust.
 Identities = 22/63 (34%), Positives = 33/63 (52%), Gaps = 3/63 (4%)
 Frame = -3

Query: 705 GYTPLHVASHYGNIKLVKFLLQ---HQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNG 761
           G TPLH+A   G + +V  L++   H   +N +  +  +PLH AA      I+ +LL  G
Sbjct: 206 GDTPLHLACISGYVDVVAALIRMAPHPCLLNIQNDVAQTPLHLAALTAQPTILRMLLLAG 27

Query: 762 ASP 764
           A P
Sbjct: 26  AEP 18

 Score = 36.2 bits (82), Expect = 0.13,   Method: Compositional matrix adjust.
 Identities = 18/47 (38%), Positives = 28/47 (59%), Gaps = 3/47 (6%)
 Frame = -3

Query: 406 ESGLTPLHVASFMGHLPIVKNLLQRGASP---NVSNVKVETPLHMAA 449
           + G TPLH+A   G++ +V  L++    P   N+ N   +TPLH+AA
Sbjct: 212 DDGDTPLHLACISGYVDVVAALIRMAPHPCLLNIQNDVAQTPLHLAA 72

 Score = 36.2 bits (82), Expect = 0.14,   Method: Compositional matrix adjust.
 Identities = 22/64 (34%), Positives = 31/64 (48%), Gaps = 3/64 (4%)
 Frame = -3

Query: 46  NQNGLNGLHLASKEGHVKMVVELLHKE---IILETTTKKGNTALHIAALAGQDEVVRELV 102
           N +G   LHLA   G+V +V  L+       +L        T LH+AAL  Q  ++R L+
Sbjct: 215 NDDGDTPLHLACISGYVDVVAALIRMAPHPCLLNIQNDVAQTPLHLAALTAQPTILRMLL 36

Query: 103 NYGA 106
             GA
Sbjct: 35  LAGA 24

 Score = 33.1 bits (74), Expect = 1.0,   Method: Compositional matrix adjust.
 Identities = 22/63 (34%), Positives = 29/63 (46%), Gaps = 3/63 (4%)
 Frame = -3

Query: 540 GFTPLHVAAKYGKVRLAELLLEHDAHP---NAAGKNGLTPLHVAVHHNNLDIVKLLLPRG 596
           G TPLH+A   G V +   L+    HP   N       TPLH+A       I+++LL  G
Sbjct: 206 GDTPLHLACISGYVDVVAALIRMAPHPCLLNIQNDVAQTPLHLAALTAQPTILRMLLLAG 27

Query: 597 GSP 599
             P
Sbjct: 26  AEP 18

 Score = 32.3 bits (72), Expect = 2.1,   Method: Compositional matrix adjust.
 Identities = 20/60 (33%), Positives = 30/60 (50%), Gaps = 3/60 (5%)
 Frame = -3

Query: 639 GVTPLHLAAQEGHTEMVALLLSKQANG---NLGNKSGLTPLHLVSQEGHVPVADVLIKHG 695
           G TPLHLA   G+ ++VA L+    +    N+ N    TPLHL +      +  +L+  G
Sbjct: 206 GDTPLHLACISGYVDVVAALIRMAPHPCLLNIQNDVAQTPLHLAALTAQPTILRMLLLAG 27

 Score = 30.4 bits (67), Expect = 6.4,   Method: Compositional matrix adjust.
 Identities = 19/70 (27%), Positives = 36/70 (51%), Gaps = 3/70 (4%)
 Frame = -3

Query: 305 KTKNGLSPIHMAAQGDHLDCVRLLLQYNAEIDDITLDH---LTPLHVAAHCGHHRVAKVL 361
           +  +G +P+H+A    ++D V  L++       + + +    TPLH+AA      + ++L
Sbjct: 218 QNDDGDTPLHLACISGYVDVVAALIRMAPHPCLLNIQNDVAQTPLHLAALTAQPTILRML 39

Query: 362 LDKGAKPNSR 371
           L  GA+P  R
Sbjct: 38  LLAGAEPTVR 9

 Score = 30.4 bits (67), Expect = 6.6,   Method: Compositional matrix adjust.
 Identities = 23/64 (35%), Positives = 31/64 (48%), Gaps = 5/64 (7%)
 Frame = -3

Query: 572 NGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWN-----GYTPLHIAAKQNQIEVARSLL 626
           +G TPLH+A     +D+V  L+    +PH    N       TPLH+AA   Q  + R LL
Sbjct: 209 DGDTPLHLACISGYVDVVAALIRM--APHPCLLNIQNDVAQTPLHLAALTAQPTILRMLL 36

Query: 627 QYGG 630
             G 
Sbjct: 35  LAGA 24
>08755
          Length = 885

 Score = 39.3 bits (90), Expect = 0.017,   Method: Composition-based stats.
 Identities = 24/74 (32%), Positives = 38/74 (51%), Gaps = 1/74 (1%)
 Frame = +3

Query: 341 DHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRAL-NGFTPLHIACKKNHIRVMELLLKTGA 399
           D  + LH+A    +  V  VLL  GA P+ +   +G TPL +A        +++L+  G+
Sbjct: 651 DGQSALHIAVK--NPEVISVLLAHGANPDVKVDGSGVTPLMLAASMTKTAALQILIGAGS 824

Query: 400 SIDAVTESGLTPLH 413
           SID    +G+  LH
Sbjct: 825 SIDCRNNAGMCALH 866

 Score = 37.0 bits (84), Expect = 0.083,   Method: Composition-based stats.
 Identities = 25/74 (33%), Positives = 39/74 (52%), Gaps = 1/74 (1%)
 Frame = +3

Query: 605 NGYTPLHIAAKQNQIEVARSLLQYGGSANAE-SVQGVTPLHLAAQEGHTEMVALLLSKQA 663
           +G + LHIA K    EV   LL +G + + +    GVTPL LAA    T  + +L+   +
Sbjct: 651 DGQSALHIAVKNP--EVISVLLAHGANPDVKVDGSGVTPLMLAASMTKTAALQILIGAGS 824

Query: 664 NGNLGNKSGLTPLH 677
           + +  N +G+  LH
Sbjct: 825 SIDCRNNAGMCALH 866
>20121
          Length = 454

 Score = 37.4 bits (85), Expect = 0.055,   Method: Compositional matrix adjust.
 Identities = 26/96 (27%), Positives = 46/96 (47%), Gaps = 1/96 (1%)
 Frame = -1

Query: 634 AESVQGVTPLH-LAAQEGHTEMVALLLSKQANGNLGNKSGLTPLHLVSQEGHVPVADVLI 692
           ++++Q   P+H L       E+  LL  K+ +    +  G T LHL    GH+    VL+
Sbjct: 367 SKTLQEEFPIHWLTWHNNFRELDRLLGLKEHDIETKDPRGRTALHLSVSLGHLESTRVLL 188

Query: 693 KHGVTVDATTRMGYTPLHVASHYGNIKLVKFLLQHQ 728
           +HG          ++ LH     G+ +LV+ +LQ++
Sbjct: 187 RHGAEAGTENNGCWSVLHEGVCSGDPELVQLILQYR 80

 Score = 35.8 bits (81), Expect = 0.16,   Method: Compositional matrix adjust.
 Identities = 26/87 (29%), Positives = 40/87 (45%), Gaps = 1/87 (1%)
 Frame = -1

Query: 246 PLHIASRRGNVI-MVRLLLDRGAQIETRTKDELTPLHCAARNGHVRISEILLDHGAPIQA 304
           P+H  +   N   + RLL  +   IET+     T LH +   GH+  + +LL HGA    
Sbjct: 343 PIHWLTWHNNFRELDRLLGLKEHDIETKDPRGRTALHLSVSLGHLESTRVLLRHGAEAGT 164

Query: 305 KTKNGLSPIHMAAQGDHLDCVRLLLQY 331
           +     S +H        + V+L+LQY
Sbjct: 163 ENNGCWSVLHEGVCSGDPELVQLILQY 83

 Score = 35.4 bits (80), Expect = 0.21,   Method: Compositional matrix adjust.
 Identities = 25/88 (28%), Positives = 39/88 (44%), Gaps = 1/88 (1%)
 Frame = -1

Query: 370 SRALNGFTPLHIACKKNHIRVMELLLKTGA-SIDAVTESGLTPLHVASFMGHLPIVKNLL 428
           S+ L    P+H     N+ R ++ LL      I+     G T LH++  +GHL   + LL
Sbjct: 367 SKTLQEEFPIHWLTWHNNFRELDRLLGLKEHDIETKDPRGRTALHLSVSLGHLESTRVLL 188

Query: 429 QRGASPNVSNVKVETPLHMAARAGHTEV 456
           + GA     N    + LH    +G  E+
Sbjct: 187 RHGAEAGTENNGCWSVLHEGVCSGDPEL 104

 Score = 33.5 bits (75), Expect = 0.86,   Method: Compositional matrix adjust.
 Identities = 16/55 (29%), Positives = 31/55 (56%)
 Frame = -1

Query: 705 GYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLK 759
           G T LH++   G+++  + LL+H A+   +    +S LH+    G  ++V L+L+
Sbjct: 250 GRTALHLSVSLGHLESTRVLLRHGAEAGTENNGCWSVLHEGVCSGDPELVQLILQ 86
>22269
          Length = 1060

 Score = 37.4 bits (85), Expect = 0.061,   Method: Compositional matrix adjust.
 Identities = 20/48 (41%), Positives = 28/48 (58%)
 Frame = +1

Query: 389 RVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPNV 436
           +VM LLLK GA+ +AV    +T  H+A+  G    +K LL +GA  N 
Sbjct: 13  KVMGLLLKYGANPNAVDRYNVTAAHLAAHSGSAQCLKTLLIKGAKANC 156

 Score = 36.6 bits (83), Expect = 0.11,   Method: Composition-based stats.
 Identities = 19/45 (42%), Positives = 25/45 (55%)
 Frame = +2

Query: 717 NIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNG 761
           N++  + L+ H AD NA  + G SPL  AA  G  D V +LLK  
Sbjct: 341 NVECARILICHGADYNATDENGESPLFMAAAAGLPDSVMMLLKQA 475

 Score = 35.4 bits (80), Expect = 0.22,   Method: Compositional matrix adjust.
 Identities = 19/44 (43%), Positives = 26/44 (59%)
 Frame = +1

Query: 327 LLLQYNAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNS 370
           LLL+Y A  + +   ++T  H+AAH G  +  K LL KGAK N 
Sbjct: 25  LLLKYGANPNAVDRYNVTAAHLAAHSGSAQCLKTLLIKGAKANC 156

 Score = 35.0 bits (79), Expect = 0.26,   Method: Composition-based stats.
 Identities = 22/57 (38%), Positives = 29/57 (50%)
 Frame = +2

Query: 274 KDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQ 330
           +D    L C   N  V  + IL+ HGA   A  +NG SP+ MAA     D V +LL+
Sbjct: 305 EDNSITLGCQKNN--VECARILICHGADYNATDENGESPLFMAAAAGLPDSVMMLLK 469

 Score = 33.1 bits (74), Expect = 1.0,   Method: Compositional matrix adjust.
 Identities = 15/44 (34%), Positives = 25/44 (56%)
 Frame = +1

Query: 558 LLLEHDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHS 601
           LLL++ A+PNA  +  +T  H+A H  +   +K LL +G   + 
Sbjct: 25  LLLKYGANPNAVDRYNVTAAHLAAHSGSAQCLKTLLIKGAKANC 156

 Score = 33.1 bits (74), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 18/42 (42%), Positives = 22/42 (52%)
 Frame = +1

Query: 625 LLQYGGSANAESVQGVTPLHLAAQEGHTEMVALLLSKQANGN 666
           LL+YG + NA     VT  HLAA  G  + +  LL K A  N
Sbjct: 28  LLKYGANPNAVDRYNVTAAHLAAHSGSAQCLKTLLIKGAKAN 153

 Score = 32.0 bits (71), Expect = 2.5,   Method: Compositional matrix adjust.
 Identities = 17/49 (34%), Positives = 26/49 (53%)
 Frame = +1

Query: 687 VADVLIKHGVTVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKT 735
           V  +L+K+G   +A  R   T  H+A+H G+ + +K LL   A  N  T
Sbjct: 16  VMGLLLKYGANPNAVDRYNVTAAHLAAHSGSAQCLKTLLIKGAKANCLT 162

 Score = 31.6 bits (70), Expect = 2.8,   Method: Composition-based stats.
 Identities = 16/43 (37%), Positives = 24/43 (55%)
 Frame = +2

Query: 96  EVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENG 138
           E  R L+ +GA+ NA  + G +PL+MAA     + V  LL+  
Sbjct: 347 ECARILICHGADYNATDENGESPLFMAAAAGLPDSVMMLLKQA 475

 Score = 31.2 bits (69), Expect = 4.4,   Method: Compositional matrix adjust.
 Identities = 17/53 (32%), Positives = 26/53 (49%)
 Frame = +1

Query: 353 GHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHIRVMELLLKTGASIDAVT 405
           G H+V  +LL  GA PN+      T  H+A      + ++ LL  GA  + +T
Sbjct: 4   GLHKVMGLLLKYGANPNAVDRYNVTAAHLAAHSGSAQCLKTLLIKGAKANCLT 162

 Score = 30.4 bits (67), Expect = 7.3,   Method: Compositional matrix adjust.
 Identities = 14/47 (29%), Positives = 24/47 (51%)
 Frame = +1

Query: 191 RTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVN 237
           +   +LL+   NP+ + +   T  H+AAH  +    + LL +GA  N
Sbjct: 13  KVMGLLLKYGANPNAVDRYNVTAAHLAAHSGSAQCLKTLLIKGAKAN 153
>05396
          Length = 1865

 Score = 37.0 bits (84), Expect = 0.068,   Method: Compositional matrix adjust.
 Identities = 23/62 (37%), Positives = 32/62 (51%), Gaps = 1/62 (1%)
 Frame = +3

Query: 507  GHTPLHTAAREGHVDTALALLEK-EASQACMTKKGFTPLHVAAKYGKVRLAELLLEHDAH 565
            G T LH A+ EG +     LL++ + S   + + GFTPL  A ++ K   AELL E    
Sbjct: 1383 GRTALHVASAEGQLQVVEFLLDRCKCSPFLVDRWGFTPLDDAVRFEKHEAAELLKERMMQ 1562

Query: 566  PN 567
             N
Sbjct: 1563 EN 1568
>04513
          Length = 434

 Score = 37.0 bits (84), Expect = 0.069,   Method: Composition-based stats.
 Identities = 25/65 (38%), Positives = 37/65 (56%), Gaps = 6/65 (9%)
 Frame = -2

Query: 250 ASRRGNVIMVRLLLDRGAQIETRTKDELTPLH--CAARNGHVRISEILLDHGA----PIQ 303
           AS+ G+   V++LLD+G Q+    K +LTPL   C +R+  V +  +L+DH A    P  
Sbjct: 433 ASKYGDKDTVQVLLDKGGQVNAVGKYKLTPLMWACCSRD-DVAVVNLLIDHHALSS*PTL 257

Query: 304 AKTKN 308
            KT N
Sbjct: 256 KKTVN 242

 Score = 30.8 bits (68), Expect = 4.7,   Method: Composition-based stats.
 Identities = 18/48 (37%), Positives = 27/48 (56%), Gaps = 1/48 (2%)
 Frame = -2

Query: 547 AAKYGKVRLAELLLEHDAHPNAAGKNGLTPLHVA-VHHNNLDIVKLLL 593
           A+KYG     ++LL+     NA GK  LTPL  A    +++ +V LL+
Sbjct: 433 ASKYGDKDTVQVLLDKGGQVNAVGKYKLTPLMWACCSRDDVAVVNLLI 290
>28671
          Length = 1156

 Score = 37.0 bits (84), Expect = 0.074,   Method: Compositional matrix adjust.
 Identities = 23/67 (34%), Positives = 34/67 (50%), Gaps = 5/67 (7%)
 Frame = +2

Query: 107 NVNAQSQKGFTPLYMAAQEN-----HLEVVKFLLENGANQNVATEDGFTPLAVALQQGHE 161
           N+++   KG T L++ A++      H  +V+ LL+NGA  N     G TP    L  G  
Sbjct: 260 NLDSADMKGDTTLHLIAKQRPLSLIHQVMVRLLLQNGALPNXVDRAGKTPSQYLLDIGSS 439

Query: 162 NVVAHLI 168
           NVV  +I
Sbjct: 440 NVVVRMI 460

 Score = 34.3 bits (77), Expect = 0.42,   Method: Compositional matrix adjust.
 Identities = 39/130 (30%), Positives = 52/130 (40%), Gaps = 44/130 (33%)
 Frame = +2

Query: 710 HVASHYGNIKLVKFLLQHQADVNAKT---------KLGY--------------------- 739
           H  S +G  +LV FLL HQA V  KT         KL +                     
Sbjct: 86  HELSAWGE-RLVDFLLDHQACVGKKTSDPLAVHLVKLAFKHATAGALRWVLKNRTIDSLN 262

Query: 740 ---------SPLHQAAQQG-----HTDIVTLLLKNGASPNEVSSNGTTPLAIAKRLGYIS 785
                    + LH  A+Q      H  +V LLL+NGA PN V   G TP      +G  +
Sbjct: 263 LDSADMKGDTTLHLIAKQRPLSLIHQVMVRLLLQNGALPNXVDRAGKTPSQYLLDIGSSN 442

Query: 786 VTDVLKVVTD 795
           V  V++++TD
Sbjct: 443 V--VVRMITD 466

 Score = 33.9 bits (76), Expect = 0.61,   Method: Compositional matrix adjust.
 Identities = 19/40 (47%), Positives = 23/40 (57%), Gaps = 5/40 (12%)
 Frame = +2

Query: 476 TPLHCAAR-----IGHTGMVKLLLENGASPNLATTAGHTP 510
           T LH  A+     + H  MV+LLL+NGA PN    AG TP
Sbjct: 290 TTLHLIAKQRPLSLIHQVMVRLLLQNGALPNXVDRAGKTP 409
>18216
          Length = 472

 Score = 36.6 bits (83), Expect = 0.099,   Method: Compositional matrix adjust.
 Identities = 24/63 (38%), Positives = 34/63 (53%)
 Frame = +2

Query: 86  LHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQNVAT 145
           L +A + GQ      +++ G +VNA    G+T    AA E HL VV+ LLE GA+ +V  
Sbjct: 221 LRLAQIXGQGGC-EGVLDKGVHVNAVDPFGWTAAMSAAFEGHLAVVQTLLEAGADLSVIN 397

Query: 146 EDG 148
             G
Sbjct: 398 RQG 406
>02351
          Length = 939

 Score = 36.6 bits (83), Expect = 0.10,   Method: Compositional matrix adjust.
 Identities = 21/64 (32%), Positives = 33/64 (51%)
 Frame = +3

Query: 238 FTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETRTKDELTPLHCAARNGHVRISEILLD 297
           +   +G T LHIA+  GNV+ V+LLL   A ++    +    L  A  +G V  +++L  
Sbjct: 453 YGKDDGRTALHIAAALGNVVYVQLLLWYCANVKVVDHEGRNALWYARTSGSVECTDLLAA 632

Query: 298 HGAP 301
            G P
Sbjct: 633 AGCP 644

 Score = 36.2 bits (82), Expect = 0.12,   Method: Compositional matrix adjust.
 Identities = 21/58 (36%), Positives = 26/58 (44%)
 Frame = +3

Query: 82  GNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGA 139
           G TALHIAA  G    V+ L+ Y ANV     +G   L+ A     +E    L   G 
Sbjct: 468 GRTALHIAAALGNVVYVQLLLWYCANVKVVDHEGRNALWYARTSGSVECTDLLAAAGC 641

 Score = 34.7 bits (78), Expect = 0.35,   Method: Compositional matrix adjust.
 Identities = 19/58 (32%), Positives = 27/58 (46%)
 Frame = +3

Query: 705 GYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGA 762
           G T LH+A+  GN+  V+ LL + A+V      G + L  A   G  +   LL   G 
Sbjct: 468 GRTALHIAAALGNVVYVQLLLWYCANVKVVDHEGRNALWYARTSGSVECTDLLAAAGC 641

 Score = 32.3 bits (72), Expect = 1.7,   Method: Compositional matrix adjust.
 Identities = 27/84 (32%), Positives = 36/84 (42%), Gaps = 4/84 (4%)
 Frame = +3

Query: 188 DDTRTAAVLLQNDPNPDVLS----KTGFTPLHIAAHYENLNVAQLLLNRGASVNFTPQNG 243
           +D R   ++L +  + D+ S      G T LHIAA   N+   QLLL   A+V      G
Sbjct: 390 EDIRNIIIILGHAASDDINSPYGKDDGRTALHIAAALGNVVYVQLLLWYCANVKVVDHEG 569

Query: 244 ITPLHIASRRGNVIMVRLLLDRGA 267
              L  A   G+V    LL   G 
Sbjct: 570 RNALWYARTSGSVECTDLLAAAGC 641

 Score = 32.0 bits (71), Expect = 2.2,   Method: Compositional matrix adjust.
 Identities = 22/63 (34%), Positives = 27/63 (42%)
 Frame = +3

Query: 639 GVTPLHLAAQEGHTEMVALLLSKQANGNLGNKSGLTPLHLVSQEGHVPVADVLIKHGVTV 698
           G T LH+AA  G+   V LLL   AN  + +  G   L      G V   D+L   G   
Sbjct: 468 GRTALHIAAALGNVVYVQLLLWYCANVKVVDHEGRNALWYARTSGSVECTDLLAAAGCPD 647

Query: 699 DAT 701
            AT
Sbjct: 648 TAT 656
>35959
          Length = 383

 Score = 35.4 bits (80), Expect = 0.21,   Method: Compositional matrix adjust.
 Identities = 22/52 (42%), Positives = 28/52 (53%), Gaps = 4/52 (7%)
 Frame = -3

Query: 348 VAAHCGH----HRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHIRVMELLL 395
           + AH GH    HR   +   KGA PN +   G+TPL  A K N I ++ LLL
Sbjct: 174 LPAHPGHPPLQHRPGSLPPQKGASPNFKDSMGYTPLIHAVKMNDITMVRLLL 19

 Score = 33.9 bits (76), Expect = 0.69,   Method: Compositional matrix adjust.
 Identities = 17/33 (51%), Positives = 21/33 (63%)
 Frame = -3

Query: 232 RGASVNFTPQNGITPLHIASRRGNVIMVRLLLD 264
           +GAS NF    G TPL  A +  ++ MVRLLLD
Sbjct: 114 KGASPNFKDSMGYTPLIHAVKMNDITMVRLLLD 16
>36917
          Length = 443

 Score = 33.1 bits (74), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 13/37 (35%), Positives = 21/37 (56%)
 Frame = -1

Query: 280 LHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMA 316
           LH AA NG++ ++E LLD+   +  +      P+H A
Sbjct: 113 LHIAAANGYIEVAEFLLDNHVSVDRQDHESWQPLHAA 3

 Score = 31.6 bits (70), Expect = 3.5,   Method: Compositional matrix adjust.
 Identities = 13/37 (35%), Positives = 22/37 (59%)
 Frame = -1

Query: 676 LHLVSQEGHVPVADVLIKHGVTVDATTRMGYTPLHVA 712
           LH+ +  G++ VA+ L+ + V+VD      + PLH A
Sbjct: 113 LHIAAANGYIEVAEFLLDNHVSVDRQDHESWQPLHAA 3

 Score = 30.8 bits (68), Expect = 5.6,   Method: Compositional matrix adjust.
 Identities = 15/37 (40%), Positives = 17/37 (45%)
 Frame = -1

Query: 379 LHIACKKNHIRVMELLLKTGASIDAVTESGLTPLHVA 415
           LHIA    +I V E LL    S+D        PLH A
Sbjct: 113 LHIAAANGYIEVAEFLLDNHVSVDRQDHESWQPLHAA 3
>20955
          Length = 1122

 Score = 31.6 bits (70), Expect = 2.9,   Method: Compositional matrix adjust.
 Identities = 17/57 (29%), Positives = 32/57 (56%), Gaps = 4/57 (7%)
 Frame = +2

Query: 107 NVNAQSQKGFTPLYMAAQENHLEV----VKFLLENGANQNVATEDGFTPLAVALQQG 159
            VNA   +GFT L++A Q+ + +V    ++FL+ +GA+  V   +  T +   + +G
Sbjct: 44  QVNAVDDRGFTLLHLATQDWNRDVGLSNIRFLMHHGADPGVKDSNSMTVIQSLVGKG 214
>18403
          Length = 434

 Score = 31.6 bits (70), Expect = 3.0,   Method: Composition-based stats.
 Identities = 23/73 (31%), Positives = 34/73 (46%), Gaps = 9/73 (12%)
 Frame = -3

Query: 900 SLIPSSPATETSDNI--------SPVASPVHTGFLVSF-MVDARGGSMRGSRHNGLRVVI 950
           S++P + +T + DNI        SP  +P     L  F MVD  GGSM+G+         
Sbjct: 276 SILPMTTSTGSMDNI*PMAVNDSSPANAPCSFRNLTEFSMVDRSGGSMKGNL-------- 121

Query: 951 PPRTCAAPTRITC 963
             RT  +P  ++C
Sbjct: 120 --RTLGSPIEMSC 88
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|40549397|ref|NP_112148.2| ankyrin repeat domain
protein 17 isoform a [Mus musculus]
         (2603 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

33484                                                                 162   1e-39
09292                                                                 117   8e-26
06253                                                                 100   7e-21
14005                                                                  99   2e-20
13462                                                                  92   2e-18
05924                                                                  90   1e-17
11295                                                                  86   3e-16
00540                                                                  84   9e-16
02114                                                                  80   1e-14
08473                                                                  75   5e-13
19166                                                                  71   5e-12
20036                                                                  64   6e-10
28494                                                                  64   1e-09
25470                                                                  62   3e-09
02055                                                                  62   3e-09
21532                                                                  59   3e-08
34789                                                                  58   4e-08
20792                                                                  57   1e-07
16561                                                                  50   6e-07
38834                                                                  54   1e-06
20884                                                                  39   1e-06
12417                                                                  52   4e-06
30978                                                                  49   3e-05
09180                                                                  48   6e-05
25464                                                                  48   6e-05
03467                                                                  48   7e-05
22305                                                                  47   1e-04
30463                                                                  47   1e-04
28691                                                                  47   1e-04
27108                                                                  46   2e-04
15772                                                                  46   2e-04
15359                                                                  44   0.001
28113                                                                  43   0.001
11861                                                                  43   0.001
03590                                                                  43   0.002
21751                                                                  35   0.004
17893                                                                  42   0.005
09451                                                                  41   0.005
28491                                                                  41   0.008
04763                                                                  40   0.011
02351                                                                  40   0.012
33144                                                                  39   0.033
35952                                                                  39   0.037
30217                                                                  39   0.040
27376                                                                  39   0.041
36879                                                                  37   0.13 
05396                                                                  37   0.15 
27067                                                                  36   0.17 
32680                                                                  36   0.20 
18216                                                                  36   0.20 
08755                                                                  36   0.21 
20121                                                                  34   0.68 
20988                                                                  33   1.0  
09541                                                                  33   1.5  
35959                                                                  32   2.9  
23478                                                                  32   3.2  
>33484
          Length = 436

 Score =  162 bits (410), Expect = 1e-39,   Method: Compositional matrix adjust.
 Identities = 92/144 (63%), Positives = 104/144 (72%), Gaps = 3/144 (2%)
 Frame = -2

Query: 179 GIGKLSTADGKAFADPEVLRRLTSSVSCALDEAAAALTRMRAESTANAGQSDNRSL---A 235
           GI KLS+ DGKA  DPEVLR LTSSVS ALDEA  A+  MR+E       ++   +   A
Sbjct: 435 GISKLSSKDGKALTDPEVLRTLTSSVSSALDEATQAINCMRSEQQGQTPGAEGIFVFGSA 256

Query: 236 EACSEGDVNAVRKLLIEGRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGIK 295
           +A SE D   VRKL  E  SV + TEEGESLL LACSAGYYELAQVLLAM+ANVEDRGIK
Sbjct: 255 QALSERDAGTVRKLY-ESGSVPDTTEEGESLLSLACSAGYYELAQVLLAMNANVEDRGIK 79

Query: 296 GDITPLMAAANGGHVKIVKLLLAH 319
           GD TPLM AA+GG V IV+LL+ H
Sbjct: 78  GDCTPLMEAASGGFVDIVRLLILH 7

 Score = 54.3 bits (129), Expect = 6e-07,   Method: Compositional matrix adjust.
 Identities = 27/54 (50%), Positives = 39/54 (72%), Gaps = 1/54 (1%)
 Frame = -2

Query: 1147 DTPLSLACSGGRQEVVELLLARGANKEHRNV-SDYTPLSLAASGGYVNIIKILL 1199
            ++ LSLACS G  E+ ++LLA  AN E R +  D TPL  AASGG+V+I+++L+
Sbjct: 174  ESLLSLACSAGYYELAQVLLAMNANVEDRGIKGDCTPLMEAASGGFVDIVRLLI 13

 Score = 52.4 bits (124), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 25/55 (45%), Positives = 36/55 (65%), Gaps = 1/55 (1%)
 Frame = -2

Query: 330 GNTALTYACAGGYVDVVKVLLESGASIEDHNENGH-TPLMEAGSAGHVEVARLLL 383
           G + L+ AC+ GY ++ +VLL   A++ED    G  TPLMEA S G V++ RLL+
Sbjct: 177 GESLLSLACSAGYYELAQVLLAMNANVEDRGIKGDCTPLMEAASGGFVDIVRLLI 13

 Score = 50.1 bits (118), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 26/51 (50%), Positives = 34/51 (66%), Gaps = 1/51 (1%)
 Frame = -2

Query: 1252 LTLACFQGRTEVVSLLLDRKANVEHRAKTG-LTPLMEAASGGYAEVGRVLL 1301
            L+LAC  G  E+  +LL   ANVE R   G  TPLMEAASGG+ ++ R+L+
Sbjct: 165  LSLACSAGYYELAQVLLAMNANVEDRGIKGDCTPLMEAASGGFVDIVRLLI 13

 Score = 46.6 bits (109), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 24/73 (32%), Positives = 44/73 (60%), Gaps = 1/73 (1%)
 Frame = -2

Query: 1298 RVLLDKGADVNAPPVPSSRDTALTIAADKGHYKFCELLIGKGAHIDVRNKKGN-TPLWLA 1356
            R L + G   + P      ++ L++A   G+Y+  ++L+   A+++ R  KG+ TPL  A
Sbjct: 222  RKLYESG---SVPDTTEEGESLLSLACSAGYYELAQVLLAMNANVEDRGIKGDCTPLMEA 52

Query: 1357 ANGGHLDVVQLLV 1369
            A+GG +D+V+LL+
Sbjct: 51   ASGGFVDIVRLLI 13

 Score = 44.7 bits (104), Expect = 6e-04,   Method: Compositional matrix adjust.
 Identities = 29/72 (40%), Positives = 43/72 (59%), Gaps = 1/72 (1%)
 Frame = -2

Query: 576 VKYLLAAGANVHATTATGDTALTYACENGHTDVADVLLQAGADLEHES-EGGRTPLMKAA 634
           V+ L  +G +V  TT  G++ L+ AC  G+ ++A VLL   A++E    +G  TPLM+AA
Sbjct: 225 VRKLYESG-SVPDTTEEGESLLSLACSAGYYELAQVLLAMNANVEDRGIKGDCTPLMEAA 49

Query: 635 RAGHVCTVQFLI 646
             G V  V+ LI
Sbjct: 48  SGGFVDIVRLLI 13

 Score = 39.7 bits (91), Expect = 0.018,   Method: Compositional matrix adjust.
 Identities = 28/72 (38%), Positives = 41/72 (56%), Gaps = 1/72 (1%)
 Frame = -2

Query: 380 RLLLENGAGINTHSNEFKESALTLACYKGHLEMVRFLLEAGADQEHKTDEMH-TALMEAC 438
           R L E+G+  +T   E  ES L+LAC  G+ E+ + LL   A+ E +  +   T LMEA 
Sbjct: 222 RKLYESGSVPDT--TEEGESLLSLACSAGYYELAQVLLAMNANVEDRGIKGDCTPLMEAA 49

Query: 439 MDGHVEVARLLL 450
             G V++ RLL+
Sbjct: 48  SGGFVDIVRLLI 13

 Score = 38.9 bits (89), Expect = 0.026,   Method: Compositional matrix adjust.
 Identities = 22/59 (37%), Positives = 34/59 (57%), Gaps = 1/59 (1%)
 Frame = -2

Query: 656 TANNDHTVLSLACAGGHLAVVELLLAHGADPTHR-LKDGSTMLIEAAKGGHTSVVCYLL 713
           T     ++LSLAC+ G+  + ++LLA  A+   R +K   T L+EAA GG   +V  L+
Sbjct: 189 TTEEGESLLSLACSAGYYELAQVLLAMNANVEDRGIKGDCTPLMEAASGGFVDIVRLLI 13

 Score = 37.4 bits (85), Expect = 0.083,   Method: Compositional matrix adjust.
 Identities = 25/72 (34%), Positives = 42/72 (58%)
 Frame = -2

Query: 1095 VQTLLERGASIEHRDKKGFTPLILAATAGHVGVVEILLDNGADIEAQSERTKDTPLSLAC 1154
            V+ L E G S+    ++G + L LA +AG+  + ++LL   A++E +  +   TPL  A 
Sbjct: 225  VRKLYESG-SVPDTTEEGESLLSLACSAGYYELAQVLLAMNANVEDRGIKGDCTPLMEAA 49

Query: 1155 SGGRQEVVELLL 1166
            SGG  ++V LL+
Sbjct: 48   SGGFVDIVRLLI 13

 Score = 37.0 bits (84), Expect = 0.10,   Method: Compositional matrix adjust.
 Identities = 22/52 (42%), Positives = 29/52 (55%)
 Frame = -2

Query: 1183 LSLAASGGYVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHTAAVKLLL 1234
            LSLA S GY  + ++LL   A +  R G K   +PLM AA  G    V+LL+
Sbjct: 165  LSLACSAGYYELAQVLLAMNANVEDR-GIKGDCTPLMEAASGGFVDIVRLLI 13

 Score = 35.4 bits (80), Expect = 0.33,   Method: Compositional matrix adjust.
 Identities = 18/47 (38%), Positives = 28/47 (59%), Gaps = 4/47 (8%)
 Frame = -2

Query: 538 CCGGFLEVADFLIKAGADIE----LGCSTPLMEAAQEGHLELVKYLL 580
           C  G+ E+A  L+   A++E     G  TPLMEAA  G +++V+ L+
Sbjct: 153 CSAGYYELAQVLLAMNANVEDRGIKGDCTPLMEAASGGFVDIVRLLI 13

 Score = 34.3 bits (77), Expect = 0.69,   Method: Compositional matrix adjust.
 Identities = 21/60 (35%), Positives = 30/60 (50%)
 Frame = -2

Query: 623 SEGGRTPLMKAARAGHVCTVQFLISKGANVNRTTANNDHTVLSLACAGGHLAVVELLLAH 682
           +E G + L  A  AG+    Q L++  ANV       D T L  A +GG + +V LL+ H
Sbjct: 186 TEEGESLLSLACSAGYYELAQVLLAMNANVEDRGIKGDCTPLMEAASGGFVDIVRLLILH 7
>09292
          Length = 1486

 Score =  117 bits (292), Expect = 8e-26,   Method: Compositional matrix adjust.
 Identities = 103/352 (29%), Positives = 160/352 (45%), Gaps = 35/352 (9%)
 Frame = -2

Query: 1063 LPIYPAIDIDAQT-ESNHDTALTLACAGGHEELVQTLLERGASIEHRDKKGFTPLILAAT 1121
            L  Y  I +   T +S+H+TAL   C  G  ++   LL+  A +  R+    TPL + A 
Sbjct: 1413 LLAYLDIGMHVDTRDSHHETALHAVCYVGSVKMASVLLKHXADVNARNNVDRTPLHIXAI 1234

Query: 1122 AGHVGVVEILLDNGADIEAQSERTKDTPLSLACSGGRQEVVELLLARGANKEHRNVSDYT 1181
             GH+G+VE L+ +GAD  A+ ++   TP+  AC     ++V  LL  GA    R  +   
Sbjct: 1233 EGHLGLVEELVRHGADFNAE-DKDHLTPVFNACVKNDTDIVRYLLESGA----RANTTAR 1069

Query: 1182 PLSLAASGGYVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHTAAVKLLLDMGSDIN 1241
            P+  A   GY  I+++LL  GA +NS  G+K   SPL +A  NG+    + ++  G+++N
Sbjct: 1068 PIFHAVKYGYSEIVQLLLVHGAAVNSLPGTK---SPLHIACRNGNIEMARTVIIAGANVN 898

Query: 1242 -------------------AQI--------------ETNRNTALTLACFQGRTEVVSLLL 1268
                               AQ+                N+   L LAC     E   LLL
Sbjct: 897  AVDKDGNTPLHISVRAPSSAQLVRLLIRFGANVKWGNDNQQIPLHLACLYSNLETARLLL 718

Query: 1269 DRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADVNAPPVPSSRDTA-LTIAADKG 1327
               +     +    TPL  A  GG  ++ R++L   +DVN+   P  R+ A L +A  K 
Sbjct: 717  HCGSCSNELSSKLWTPLHYAVIGGNVDIVRLVLQGSSDVNS---PDGRNNAPLHLACMKQ 547

Query: 1328 HYKFCELLIGKGAHIDVRNKKGNTPLWLAANGGHLDVVQLLVQATADVDAAD 1379
                   L+  GA+++V    G TPL +A +  +L++V LL    A+    D
Sbjct: 546  CIGIARCLLRHGANVNVSGYNGRTPLHIAISHHNLELVLLLYMCGANDQLVD 391

 Score =  110 bits (275), Expect = 8e-24,   Method: Compositional matrix adjust.
 Identities = 98/334 (29%), Positives = 155/334 (46%), Gaps = 5/334 (1%)
 Frame = -2

Query: 323  VNAQSSTGNTALTYACAGGYVDVVKVLLESGASIEDHNENGHTPLMEAGSAGHVEVARLL 382
            V+ + S   TAL   C  G V +  VLL+  A +   N    TPL      GH+ +   L
Sbjct: 1383 VDTRDSHHETALHAVCYVGSVKMASVLLKHXADVNARNNVDRTPLHIXAIEGHLGLVEEL 1204

Query: 383  LENGAGINTHSNEFKESALTLACYKGHLEMVRFLLEAGADQEHKTDEMHTALMEACMDGH 442
            + +GA  N    +        AC K   ++VR+LLE+GA    + +     +  A   G+
Sbjct: 1203 VRHGADFNAEDKDHLTPVFN-ACVKNDTDIVRYLLESGA----RANTTARPIFHAVKYGY 1039

Query: 443  VEVARLLLDSGAQVN-MPADSFESPLTLAACGGHVELAALLIERGASLEEVNDEGYTPLM 501
             E+ +LLL  GA VN +P    +SPL +A   G++E+A  +I  GA++  V+ +G TPL 
Sbjct: 1038 SEIVQLLLVHGAAVNSLPGT--KSPLHIACRNGNIEMARTVIIAGANVNAVDKDGNTPLH 865

Query: 502  EAARE-GHEEMVALLLGQGANINXXXXXXXXXXXXXXCCGGFLEVADFLIKAGA---DIE 557
             + R     ++V LL+  GAN+               C    LE A  L+  G+   ++ 
Sbjct: 864  ISVRAPSSAQLVRLLIRFGANV-KWGNDNQQIPLHLACLYSNLETARLLLHCGSCSNELS 688

Query: 558  LGCSTPLMEAAQEGHLELVKYLLAAGANVHATTATGDTALTYACENGHTDVADVLLQAGA 617
                TPL  A   G++++V+ +L   ++V++     +  L  AC      +A  LL+ GA
Sbjct: 687  SKLWTPLHYAVIGGNVDIVRLVLQGSSDVNSPDGRNNAPLHLACMKQCIGIARCLLRHGA 508

Query: 618  DLEHESEGGRTPLMKAARAGHVCTVQFLISKGAN 651
            ++      GRTPL  A    ++  V  L   GAN
Sbjct: 507  NVNVSGYNGRTPLHIAISHHNLELVLLLYMCGAN 406

 Score =  103 bits (258), Expect = 7e-22,   Method: Compositional matrix adjust.
 Identities = 88/320 (27%), Positives = 155/320 (48%), Gaps = 4/320 (1%)
 Frame = -2

Query: 206  CALDEAAAALTRMRAESTANAGQSDNRS-LAEACSEGDVNAVRKLLIEGRSVNEHTEEGE 264
            C +     A   ++  +  NA  + +R+ L     EG +  V +L+  G   N   ++  
Sbjct: 1338 CYVGSVKMASVLLKHXADVNARNNVDRTPLHIXAIEGHLGLVEELVRHGADFNAEDKDHL 1159

Query: 265  SLLCLACSAGYYELAQVLLAMHANVEDRGIKGDIT--PLMAAANGGHVKIVKLLLAHKAD 322
            + +  AC     ++ + LL       + G + + T  P+  A   G+ +IV+LLL H A 
Sbjct: 1158 TPVFNACVKNDTDIVRYLL-------ESGARANTTARPIFHAVKYGYSEIVQLLLVHGAA 1000

Query: 323  VNAQSSTGNTALTYACAGGYVDVVKVLLESGASIEDHNENGHTPL-MEAGSAGHVEVARL 381
            VN+   T  + L  AC  G +++ + ++ +GA++   +++G+TPL +   +    ++ RL
Sbjct: 999  VNSLPGT-KSPLHIACRNGNIEMARTVIIAGANVNAVDKDGNTPLHISVRAPSSAQLVRL 823

Query: 382  LLENGAGINTHSNEFKESALTLACYKGHLEMVRFLLEAGADQEHKTDEMHTALMEACMDG 441
            L+  GA +    N+ ++  L LAC   +LE  R LL  G+     + ++ T L  A + G
Sbjct: 822  LIRFGANVKW-GNDNQQIPLHLACLYSNLETARLLLHCGSCSNELSSKLWTPLHYAVIGG 646

Query: 442  HVEVARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALLIERGASLEEVNDEGYTPLM 501
            +V++ RL+L   + VN P     +PL LA     + +A  L+  GA++      G TPL 
Sbjct: 645  NVDIVRLVLQGSSDVNSPDGRNNAPLHLACMKQCIGIARCLLRHGANVNVSGYNGRTPLH 466

Query: 502  EAAREGHEEMVALLLGQGAN 521
             A    + E+V LL   GAN
Sbjct: 465  IAISHHNLELVLLLYMCGAN 406

 Score = 90.9 bits (224), Expect = 7e-18,   Method: Compositional matrix adjust.
 Identities = 93/351 (26%), Positives = 153/351 (43%), Gaps = 3/351 (0%)
 Frame = -2

Query: 338  CAGGYVDVVKVL--LESGASIEDHNENGHTPLMEAGSAGHVEVARLLLENGAGINTHSNE 395
            CA    DV  +L  L+ G  ++  + +  T L      G V++A +LL++ A +N  +N 
Sbjct: 1443 CAXQLQDVETLLAYLDIGMHVDTRDSHHETALHAVCYVGSVKMASVLLKHXADVNARNN- 1267

Query: 396  FKESALTLACYKGHLEMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQ 455
               + L +   +GHL +V  L+  GAD   +  +  T +  AC+    ++ R LL+SGA+
Sbjct: 1266 VDRTPLHIXAIEGHLGLVEELVRHGADFNAEDKDHLTPVFNACVKNDTDIVRYLLESGAR 1087

Query: 456  VNMPADSFESPLTLAACGGHVELAALLIERGASLEEVNDEGYTPLMEAAREGHEEMVALL 515
             N  A     P+  A   G+ E+  LL+  GA++  +     +PL  A R G+ EM   +
Sbjct: 1086 ANTTA----RPIFHAVKYGYSEIVQLLLVHGAAVNSLPGTK-SPLHIACRNGNIEMARTV 922

Query: 516  LGQGANINXXXXXXXXXXXXXXCCGGFLEVADFLIKAGADIELGCSTPLMEAAQE-GHLE 574
            +  GAN+N                                ++   +TPL  + +     +
Sbjct: 921  IIAGANVNA-------------------------------VDKDGNTPLHISVRAPSSAQ 835

Query: 575  LVKYLLAAGANVHATTATGDTALTYACENGHTDVADVLLQAGADLEHESEGGRTPLMKAA 634
            LV+ L+  GANV          L  AC   + + A +LL  G+     S    TPL  A 
Sbjct: 834  LVRLLIRFGANVKWGNDNQQIPLHLACLYSNLETARLLLHCGSCSNELSSKLWTPLHYAV 655

Query: 635  RAGHVCTVQFLISKGANVNRTTANNDHTVLSLACAGGHLAVVELLLAHGAD 685
              G+V  V+ ++   ++VN     N+   L LAC    + +   LL HGA+
Sbjct: 654  IGGNVDIVRLVLQGSSDVNSPDGRNN-APLHLACMKQCIGIARCLLRHGAN 505

 Score = 59.7 bits (143), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 51/163 (31%), Positives = 79/163 (48%), Gaps = 3/163 (1%)
 Frame = -2

Query: 538  CCGGFLEVADFLIKAGADIELGCS---TPLMEAAQEGHLELVKYLLAAGANVHATTATGD 594
            C  G +++A  L+K  AD+    +   TPL   A EGHL LV+ L+  GA+ +A      
Sbjct: 1338 CYVGSVKMASVLLKHXADVNARNNVDRTPLHIXAIEGHLGLVEELVRHGADFNAEDKDHL 1159

Query: 595  TALTYACENGHTDVADVLLQAGADLEHESEGGRTPLMKAARAGHVCTVQFLISKGANVNR 654
            T +  AC    TD+   LL++GA     +     P+  A + G+   VQ L+  GA VN 
Sbjct: 1158 TPVFNACVKNDTDIVRYLLESGA----RANTTARPIFHAVKYGYSEIVQLLLVHGAAVNS 991

Query: 655  TTANNDHTVLSLACAGGHLAVVELLLAHGADPTHRLKDGSTML 697
                   + L +AC  G++ +   ++  GA+     KDG+T L
Sbjct: 990  LPGTK--SPLHIACRNGNIEMARTVIIAGANVNAVDKDGNTPL 868

 Score = 56.6 bits (135), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 36/103 (34%), Positives = 52/103 (50%)
 Frame = -2

Query: 1301 LDKGADVNAPPVPSSRDTALTIAADKGHYKFCELLIGKGAHIDVRNKKGNTPLWLAANGG 1360
            LD G  V+     S  +TAL      G  K   +L+   A ++ RN    TPL + A  G
Sbjct: 1401 LDIGMHVDTRD--SHHETALHAVCYVGSVKMASVLLKHXADVNARNNVDRTPLHIXAIEG 1228

Query: 1361 HLDVVQLLVQATADVDAADNRKITPLMAAFRKGHVKVVRYLVK 1403
            HL +V+ LV+  AD +A D   +TP+  A  K    +VRYL++
Sbjct: 1227 HLGLVEELVRHGADFNAEDKDHLTPVFNACVKNDTDIVRYLLE 1099

 Score = 48.5 bits (114), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 47/151 (31%), Positives = 68/151 (45%), Gaps = 1/151 (0%)
 Frame = -2

Query: 564  LMEAAQEGHLELVKYLLAAGANVHATTATGDTALTYACENGHTDVADVLLQAGADLEHES 623
            L  A Q   +E +   L  G +V    +  +TAL   C  G   +A VLL+  AD+   +
Sbjct: 1449 LHCAXQLQDVETLLAYLDIGMHVDTRDSHHETALHAVCYVGSVKMASVLLKHXADVNARN 1270

Query: 624  EGGRTPLMKAARAGHVCTVQFLISKGANVNRTTANNDH-TVLSLACAGGHLAVVELLLAH 682
               RTPL   A  GH+  V+ L+  GA+ N    + DH T +  AC      +V  LL  
Sbjct: 1269 NVDRTPLHIXAIEGHLGLVEELVRHGADFN--AEDKDHLTPVFNACVKNDTDIVRYLLES 1096

Query: 683  GADPTHRLKDGSTMLIEAAKGGHTSVVCYLL 713
            GA    R    +  +  A K G++ +V  LL
Sbjct: 1095 GA----RANTTARPIFHAVKYGYSEIVQLLL 1015

 Score = 39.7 bits (91), Expect = 0.016,   Method: Compositional matrix adjust.
 Identities = 22/75 (29%), Positives = 38/75 (50%)
 Frame = -2

Query: 1339 GAHIDVRNKKGNTPLWLAANGGHLDVVQLLVQATADVDAADNRKITPLMAAFRKGHVKVV 1398
            G H+D R+    T L      G + +  +L++  ADV+A +N   TPL     +GH+ +V
Sbjct: 1392 GMHVDTRDSHHETALHAVCYVGSVKMASVLLKHXADVNARNNVDRTPLHIXAIEGHLGLV 1213

Query: 1399 RYLVKEVNQFPSDSE 1413
              LV+    F ++ +
Sbjct: 1212 EELVRHGADFNAEDK 1168
>06253
          Length = 1049

 Score =  100 bits (249), Expect = 7e-21,   Method: Compositional matrix adjust.
 Identities = 93/261 (35%), Positives = 128/261 (49%), Gaps = 1/261 (0%)
 Frame = -1

Query: 1081 TALTLACAGGHEELVQTLLERGASIEHRDKKGFTPLILAATAGHVGVVEILLDNGADIEA 1140
            T L  A   G +++V+ LLE GA++  RD  G  PL  A + GH  VV++LL +GAD  A
Sbjct: 1040 TPLHFAAGFGRKDVVEHLLENGANVHARDDGGLIPLHNACSFGHAEVVQLLLRHGADPNA 861

Query: 1141 QSERTKDTPLSLACSGGRQEVVELLLARGANKEHRNVSDYTPLSLAASGGYVNIIKILLN 1200
            + +    TPL  A   G+ +V  +LL + A+   RN    T L LA +       K +L 
Sbjct: 860  R-DNWNYTPLHEAAIKGKIDVCIVLLQQCADPNIRNTDGKTALDLADASA-----KAVL- 702

Query: 1201 AGAEINSRTGSKLGISPLMLAAMNGHTAAVKLLLDMGSDINAQIETNR-NTALTLACFQG 1259
                    TG +     L+ AA +G+   +  LL    ++N      R +T L LA    
Sbjct: 701  --------TG-EYKKDELLEAARSGNEEQMMALL-TPLNVNCHASDGRKSTPLHLAAGYN 552

Query: 1260 RTEVVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADVNAPPVPSSRDTA 1319
            RT +V LLL   A+V  + K GL PL  A S G+ EV  +LL  GA VNA  V   + T 
Sbjct: 551  RTRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHFEVTEMLLXAGASVNA--VDLWQFTP 378

Query: 1320 LTIAADKGHYKFCELLIGKGA 1340
            L  AA K   + C LL+  GA
Sbjct: 377  LHEAASKSRVEVCSLLLAHGA 315

 Score =  100 bits (248), Expect = 9e-21,   Method: Compositional matrix adjust.
 Identities = 84/257 (32%), Positives = 120/257 (46%)
 Frame = -1

Query: 1146 KDTPLSLACSGGRQEVVELLLARGANKEHRNVSDYTPLSLAASGGYVNIIKILLNAGAEI 1205
            K TPL  A   GR++VVE LL  GAN   R+     PL  A S G+  ++++LL  GA+ 
Sbjct: 1046 KSTPLHFAAGFGRKDVVEHLLENGANVHARDDGGLIPLHNACSFGHAEVVQLLLRHGADP 867

Query: 1206 NSRTGSKLGISPLMLAAMNGHTAAVKLLLDMGSDINAQIETNRNTALTLACFQGRTEVVS 1265
            N+R       +PL  AA+ G      +LL   +D N +  T+  TAL LA          
Sbjct: 866  NAR--DNWNYTPLHEAAIKGKIDVCIVLLQQCADPNIR-NTDGKTALDLA---------- 726

Query: 1266 LLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADVNAPPVPSSRDTALTIAAD 1325
               D  A      +     L+EAA  G  E    LL    +VN       + T L +AA 
Sbjct: 725  ---DASAKAVLTGEYKKDELLEAARSGNEEQMMALLTP-LNVNCHASDGRKSTPLHLAAG 558

Query: 1326 KGHYKFCELLIGKGAHIDVRNKKGNTPLWLAANGGHLDVVQLLVQATADVDAADNRKITP 1385
                +  +LL+  GA +  ++K G  PL  A + GH +V ++L+ A A V+A D  + TP
Sbjct: 557  YNRTRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHFEVTEMLLXAGASVNAVDLWQFTP 378

Query: 1386 LMAAFRKGHVKVVRYLV 1402
            L  A  K  V+V   L+
Sbjct: 377  LHEAASKSRVEVCSLLL 327

 Score = 92.8 bits (229), Expect = 1e-18,   Method: Compositional matrix adjust.
 Identities = 83/248 (33%), Positives = 113/248 (45%), Gaps = 1/248 (0%)
 Frame = -1

Query: 441  GHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALLIERGASLEEVNDEGYTPL 500
            G  +V   LL++GA V+   D    PL  A   GH E+  LL+  GA     ++  YTPL
Sbjct: 1013 GRKDVVEHLLENGANVHARDDGGLIPLHNACSFGHAEVVQLLLRHGADPNARDNWNYTPL 834

Query: 501  MEAAREGHEEMVALLLGQGANINXXXXXXXXXXXXXXCCGGFLEVADFLIKAGADIELGC 560
             EAA +G  ++  +LL Q A+ N                   L++AD   KA    E   
Sbjct: 833  HEAAIKGKIDVCIVLLQQCADPNIRNTDGKTA----------LDLADASAKAVLTGEYK- 687

Query: 561  STPLMEAAQEGHLELVKYLLA-AGANVHATTATGDTALTYACENGHTDVADVLLQAGADL 619
               L+EAA+ G+ E +  LL     N HA+     T L  A     T +  +LLQ GAD+
Sbjct: 686  KDELLEAARSGNEEQMMALLTPLNVNCHASDGRKSTPLHLAAGYNRTRIVQLLLQHGADV 507

Query: 620  EHESEGGRTPLMKAARAGHVCTVQFLISKGANVNRTTANNDHTVLSLACAGGHLAVVELL 679
              + +GG  PL  A   GH    + L+  GA+VN        T L  A +   + V  LL
Sbjct: 506  HAKDKGGLVPLHNACSYGHFEVTEMLLXAGASVNAVDLWQ-FTPLHEAASKSRVEVCSLL 330

Query: 680  LAHGADPT 687
            LAHGADP 
Sbjct: 329  LAHGADPN 306

 Score = 87.8 bits (216), Expect = 5e-17,   Method: Compositional matrix adjust.
 Identities = 77/245 (31%), Positives = 113/245 (46%), Gaps = 20/245 (8%)
 Frame = -1

Query: 299  TPLMAAANGGHVKIVKLLLAHKADVNAQSSTGNTALTYACAGGYVDVVKVLLESGASIED 358
            TPL  AA  G   +V+ LL + A+V+A+   G   L  AC+ G+ +VV++LL  GA    
Sbjct: 1040 TPLHFAAGFGRKDVVEHLLENGANVHARDDGGLIPLHNACSFGHAEVVQLLLRHGADPNA 861

Query: 359  HNENGHTPLMEAGSAGHVEVARLLLENGAGINTH-------------------SNEFKES 399
             +   +TPL EA   G ++V  +LL+  A  N                     + E+K+ 
Sbjct: 860  RDNWNYTPLHEAAIKGKIDVCIVLLQQCADPNIRNTDGKTALDLADASAKAVLTGEYKKD 681

Query: 400  ALTLACYKGHLEMVRFLLEAGADQEHKTD-EMHTALMEACMDGHVEVARLLLDSGAQVNM 458
             L  A   G+ E +  LL       H +D    T L  A       + +LLL  GA V+ 
Sbjct: 680  ELLEAARSGNEEQMMALLTPLNVNCHASDGRKSTPLHLAAGYNRTRIVQLLLQHGADVHA 501

Query: 459  PADSFESPLTLAACGGHVELAALLIERGASLEEVNDEGYTPLMEAAREGHEEMVALLLGQ 518
                   PL  A   GH E+  +L+  GAS+  V+   +TPL EAA +   E+ +LLL  
Sbjct: 500  KDKGGLVPLHNACSYGHFEVTEMLLXAGASVNAVDLWQFTPLHEAASKSRVEVCSLLLAH 321

Query: 519  GANIN 523
            GA+ N
Sbjct: 320  GADPN 306

 Score = 87.0 bits (214), Expect = 9e-17,   Method: Compositional matrix adjust.
 Identities = 82/258 (31%), Positives = 120/258 (46%), Gaps = 4/258 (1%)
 Frame = -1

Query: 332  TALTYACAGGYVDVVKVLLESGASIEDHNENGHTPLMEAGSAGHVEVARLLLENGAGINT 391
            T L +A   G  DVV+ LLE+GA++   ++ G  PL  A S GH EV +LLL +GA  N 
Sbjct: 1040 TPLHFAAGFGRKDVVEHLLENGANVHARDDGGLIPLHNACSFGHAEVVQLLLRHGADPNA 861

Query: 392  HSNEFKESALTLACYKGHLEMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLD 451
              N +  + L  A  KG +++   LL+  AD   +  +  TAL              L D
Sbjct: 860  RDN-WNYTPLHEAAIKGKIDVCIVLLQQCADPNIRNTDGKTALD-------------LAD 723

Query: 452  SGAQVNMPADSFESPLTLAACGGHVE-LAALLIERGASLEEVNDEGYTPLMEAAREGHEE 510
            + A+  +  +  +  L  AA  G+ E + ALL     +    +    TPL  AA      
Sbjct: 722  ASAKAVLTGEYKKDELLEAARSGNEEQMMALLTPLNVNCHASDGRKSTPLHLAAGYNRTR 543

Query: 511  MVALLLGQGANINXXXXXXXXXXXXXXCCGGFLEVADFLIKAGAD---IELGCSTPLMEA 567
            +V LLL  GA+++              C  G  EV + L+ AGA    ++L   TPL EA
Sbjct: 542  IVQLLLQHGADVH-AKDKGGLVPLHNACSYGHFEVTEMLLXAGASVNAVDLWQFTPLHEA 366

Query: 568  AQEGHLELVKYLLAAGAN 585
            A +  +E+   LLA GA+
Sbjct: 365  ASKSRVEVCSLLLAHGAD 312

 Score = 86.7 bits (213), Expect = 1e-16,   Method: Compositional matrix adjust.
 Identities = 82/248 (33%), Positives = 113/248 (45%), Gaps = 21/248 (8%)
 Frame = -1

Query: 267  LCLACSAGYYELAQVLLAMHANVEDRGIKGDITPLMAAANGGHVKIVKLLLAHKADVNAQ 326
            L  A   G  ++ + LL   ANV  R   G + PL  A + GH ++V+LLL H AD NA+
Sbjct: 1034 LHFAAGFGRKDVVEHLLENGANVHARD-DGGLIPLHNACSFGHAEVVQLLLRHGADPNAR 858

Query: 327  SSTGNTALTYACAGGYVDVVKVLLESGASIEDHNENGHTP-------------------- 366
             +   T L  A   G +DV  VLL+  A     N +G T                     
Sbjct: 857  DNWNYTPLHEAAIKGKIDVCIVLLQQCADPNIRNTDGKTALDLADASAKAVLTGEYKKDE 678

Query: 367  LMEAGSAGHVEVARLLLENGAGINTHSNEFKESA-LTLACYKGHLEMVRFLLEAGADQEH 425
            L+EA  +G+ E    LL     +N H+++ ++S  L LA       +V+ LL+ GAD   
Sbjct: 677  LLEAARSGNEEQMMALL-TPLNVNCHASDGRKSTPLHLAAGYNRTRIVQLLLQHGADVHA 501

Query: 426  KTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALLIER 485
            K       L  AC  GH EV  +LL +GA VN       +PL  AA    VE+ +LL+  
Sbjct: 500  KDKGGLVPLHNACSYGHFEVTEMLLXAGASVNAVDLWQFTPLHEAASKSRVEVCSLLLAH 321

Query: 486  GASLEEVN 493
            GA    VN
Sbjct: 320  GADPNLVN 297

 Score = 81.6 bits (200), Expect = 4e-15,   Method: Compositional matrix adjust.
 Identities = 83/278 (29%), Positives = 114/278 (41%), Gaps = 21/278 (7%)
 Frame = -1

Query: 397  KESALTLACYKGHLEMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQV 456
            K + L  A   G  ++V  LLE GA+   + D     L  AC  GH EV +LLL  GA  
Sbjct: 1046 KSTPLHFAAGFGRKDVVEHLLENGANVHARDDGGLIPLHNACSFGHAEVVQLLLRHGADP 867

Query: 457  NMPADSFESPLTLAACGGHVELAALLIERGASLEEVNDEGYTP----------------- 499
            N   +   +PL  AA  G +++  +L+++ A     N +G T                  
Sbjct: 866  NARDNWNYTPLHEAAIKGKIDVCIVLLQQCADPNIRNTDGKTALDLADASAKAVLTGEYK 687

Query: 500  ---LMEAAREGHEE-MVALLLGQGANINXXXXXXXXXXXXXXCCGGFLEVADFLIKAGAD 555
               L+EAAR G+EE M+ALL     N +                                
Sbjct: 686  KDELLEAARSGNEEQMMALLTPLNVNCHASDGRK-------------------------- 585

Query: 556  IELGCSTPLMEAAQEGHLELVKYLLAAGANVHATTATGDTALTYACENGHTDVADVLLQA 615
                 STPL  AA      +V+ LL  GA+VHA    G   L  AC  GH +V ++LL A
Sbjct: 584  -----STPLHLAAGYNRTRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHFEVTEMLLXA 420

Query: 616  GADLEHESEGGRTPLMKAARAGHVCTVQFLISKGANVN 653
            GA +        TPL +AA    V     L++ GA+ N
Sbjct: 419  GASVNAVDLWQFTPLHEAASKSRVEVCSLLLAHGADPN 306

 Score = 76.3 bits (186), Expect = 2e-13,   Method: Compositional matrix adjust.
 Identities = 69/227 (30%), Positives = 106/227 (46%), Gaps = 22/227 (9%)
 Frame = -1

Query: 1076 ESNHDTALTLACAGGHEELVQTLLERGASIEHRDKKGFTPLILAATAGHVGVVEILLDNG 1135
            E   D  L  A +G  E+++  L     +    D +  TPL LAA      +V++LL +G
Sbjct: 695  EYKKDELLEAARSGNEEQMMALLTPLNVNCHASDGRKSTPLHLAAGYNRTRIVQLLLQHG 516

Query: 1136 ADIEAQSERTKDTPLSLACSGGRQEVVELLLARGANKEHRNVSDYTPLSLAASGGYVNII 1195
            AD+ A+ ++    PL  ACS G  EV E+LL  GA+    ++  +TPL  AAS   V + 
Sbjct: 515  ADVHAK-DKGGLVPLHNACSYGHFEVTEMLLXAGASVNAVDLWQFTPLHEAASKSRVEVC 339

Query: 1196 KILLNAGAE---INSRTGSKLGISP----------------LMLAAMNGHTAAVKLLLDM 1236
             +LL  GA+   +N  + S + ++P                L+  A     A VK  L +
Sbjct: 338  SLLLAHGADPNLVNCHSKSIIDVAPTRELQERIQFEYKGHSLLEGARQADLARVKKYLAV 159

Query: 1237 GSDINAQIETNRNTALTLAC---FQGRTEVVSLLLDRKANVEHRAKT 1280
               +N +   N +TAL  A    F  R +VV LL+ +  N+  + KT
Sbjct: 158  -DIVNFKHPYNGDTALHCAAASPFPKRKQVVELLVRKGGNLNEKTKT 21

 Score = 69.7 bits (169), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 73/238 (30%), Positives = 109/238 (45%), Gaps = 33/238 (13%)
 Frame = -1

Query: 205 SCALDEAAAALTRMRAESTANAGQSDNRS-LAEACSEGDVNAVRKLLIEGRSVNEHTEEG 263
           +C+   A      +R  +  NA  + N + L EA  +G ++    LL +    N    +G
Sbjct: 926 ACSFGHAEVVQLLLRHGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQQCADPNIRNTDG 747

Query: 264 ESLLCLACSA------GYYELAQVLLAMHANVEDR----------------GIKGDITPL 301
           ++ L LA ++      G Y+  ++L A  +  E++                G K   TPL
Sbjct: 746 KTALDLADASAKAVLTGEYKKDELLEAARSGNEEQMMALLTPLNVNCHASDGRKS--TPL 573

Query: 302 MAAANGGHVKIVKLLLAHKADVNAQSSTGNTALTYACAGGYVDVVKVLLESGASIEDHNE 361
             AA     +IV+LLL H ADV+A+   G   L  AC+ G+ +V ++LL +GAS+   + 
Sbjct: 572 HLAAGYNRTRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHFEVTEMLLXAGASVNAVDL 393

Query: 362 NGHTPLMEAGSAGHVEVARLLLENGAG---INTHSNEFKESALTLAC-------YKGH 409
              TPL EA S   VEV  LLL +GA    +N HS    + A T          YKGH
Sbjct: 392 WQFTPLHEAASKSRVEVCSLLLAHGADPNLVNCHSKSIIDVAPTRELQERIQFEYKGH 219

 Score = 59.7 bits (143), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 80/257 (31%), Positives = 113/257 (43%), Gaps = 4/257 (1%)
 Frame = -1

Query: 498  TPLMEAAREGHEEMVALLLGQGANINXXXXXXXXXXXXXXCCGGFLEVADFLIKAGAD-- 555
            TPL  AA  G +++V  LL  GAN++              C  G  EV   L++ GAD  
Sbjct: 1040 TPLHFAAGFGRKDVVEHLLENGANVHARDDGGLIPLHNA-CSFGHAEVVQLLLRHGADPN 864

Query: 556  -IELGCSTPLMEAAQEGHLELVKYLLAAGANVHATTATGDTALTYACENGHTDVADVLLQ 614
              +    TPL EAA +G +++   LL   A+ +     G TAL         D+AD    
Sbjct: 863  ARDNWNYTPLHEAAIKGKIDVCIVLLQQCADPNIRNTDGKTAL---------DLAD---- 723

Query: 615  AGADLEHESEGGRTPLMKAARAGHVCTVQFLISKGANVN-RTTANNDHTVLSLACAGGHL 673
            A A      E  +  L++AAR+G+   +  L++   NVN   +     T L LA      
Sbjct: 722  ASAKAVLTGEYKKDELLEAARSGNEEQMMALLTP-LNVNCHASDGRKSTPLHLAAGYNRT 546

Query: 674  AVVELLLAHGADPTHRLKDGSTMLIEAAKGGHTSVVCYLLDYPNNLLAAPPPDVTQLTPP 733
             +V+LLL HGAD   + K G   L  A   GH  V   LL    ++ A    D+ Q T P
Sbjct: 545  RIVQLLLQHGADVHAKDKGGLVPLHNACSYGHFEVTEMLLXAGASVNAV---DLWQFT-P 378

Query: 734  SHDLNRAPRVPVQALPM 750
             H+     RV V +L +
Sbjct: 377  LHEAASKSRVEVCSLLL 327

 Score = 53.5 bits (127), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 34/89 (38%), Positives = 48/89 (53%)
 Frame = -1

Query: 1316 RDTALTIAADKGHYKFCELLIGKGAHIDVRNKKGNTPLWLAANGGHLDVVQLLVQATADV 1375
            + T L  AA  G     E L+  GA++  R+  G  PL  A + GH +VVQLL++  AD 
Sbjct: 1046 KSTPLHFAAGFGRKDVVEHLLENGANVHARDDGGLIPLHNACSFGHAEVVQLLLRHGADP 867

Query: 1376 DAADNRKITPLMAAFRKGHVKVVRYLVKE 1404
            +A DN   TPL  A  KG + V   L+++
Sbjct: 866  NARDNWNYTPLHEAAIKGKIDVCIVLLQQ 780
>14005
          Length = 1745

 Score = 99.4 bits (246), Expect = 2e-20,   Method: Compositional matrix adjust.
 Identities = 76/249 (30%), Positives = 118/249 (47%), Gaps = 6/249 (2%)
 Frame = -1

Query: 397  KESALTLACYKGHLEMVRFLLEA-GADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQ 455
            +E+ L +A   GHL +V  LL+  G D   + +++  AL  ACM   +E+ + L+  GA+
Sbjct: 1745 RETPLIIASRMGHLAVVSELLKVPGIDVNERDEKLRPALYFACMGNDIELVKQLVRYGAR 1566

Query: 456  VN-MPADSFESPLTLAACGGHVELAALLIERGASLEEVNDEGYTPLMEAAREGHEEMVAL 514
            VN    +++ +P       G   +A  L+  GA+ E    +G TPL+ A +    E+  L
Sbjct: 1565 VNAYSTETWWTPFHACCKRGDPRIALYLLRHGANKESRTVDGKTPLVVACKNDKAEVALL 1386

Query: 515  LLGQGANINXXXXXXXXXXXXXXCCGGFLEVADFLIKAGADIE---LGCSTPLMEAAQEG 571
            L+  GAN+N              C    +E+   L+  GAD++       T L  A+  G
Sbjct: 1385 LIRSGANVNVSCDITANTPVHFACQRPNIELLKRLVLHGADVDKPNAKGHTALHVASVRG 1206

Query: 572  HLELVKYLL-AAGANVHATTATGDTALTYACENGHTDVADVLLQAGADLEHESEGGRTPL 630
              + V YLL    A V+A T  G+ AL  AC   H D+ ++LL  GA+    ++ G TP 
Sbjct: 1205 FKQHVIYLLDFCDAEVNAATLKGNNALHIACRGKHADLVELLLHKGANPAQRNQRGWTPR 1026

Query: 631  MKAARAGHV 639
              A R   V
Sbjct: 1025 NSAGRCXEV 999

 Score = 90.9 bits (224), Expect = 6e-18,   Method: Compositional matrix adjust.
 Identities = 67/207 (32%), Positives = 103/207 (49%), Gaps = 2/207 (0%)
 Frame = -1

Query: 301  LMAAANGGHVKIVKLLLAHKADVNAQSS-TGNTALTYACAGGYVDVVKVLLESGASIEDH 359
            L  A  G  +++VK L+ + A VNA S+ T  T     C  G   +   LL  GA+ E  
Sbjct: 1631 LYFACMGNDIELVKQLVRYGARVNAYSTETWWTPFHACCKRGDPRIALYLLRHGANKESR 1452

Query: 360  NENGHTPLMEAGSAGHVEVARLLLENGAGINTHSNEFKESALTLACYKGHLEMVRFLLEA 419
              +G TPL+ A      EVA LL+ +GA +N   +    + +  AC + ++E+++ L+  
Sbjct: 1451 TVDGKTPLVVACKNDKAEVALLLIRSGANVNVSCDITANTPVHFACQRPNIELLKRLVLH 1272

Query: 420  GADQEHKTDEMHTALMEACMDGHVEVARLLLD-SGAQVNMPADSFESPLTLAACGGHVEL 478
            GAD +    + HTAL  A + G  +    LLD   A+VN       + L +A  G H +L
Sbjct: 1271 GADVDKPNAKGHTALHVASVRGFKQHVIYLLDFCDAEVNAATLKGNNALHIACRGKHADL 1092

Query: 479  AALLIERGASLEEVNDEGYTPLMEAAR 505
              LL+ +GA+  + N  G+TP   A R
Sbjct: 1091 VELLLHKGANPAQRNQRGWTPRNSAGR 1011

 Score = 85.1 bits (209), Expect = 4e-16,   Method: Compositional matrix adjust.
 Identities = 81/275 (29%), Positives = 117/275 (42%), Gaps = 2/275 (0%)
 Frame = -1

Query: 1080 DTALTLACAGGHEELVQTLLER-GASIEHRDKKGFTPLILAATAGHVGVVEILLDNGADI 1138
            +T L +A   GH  +V  LL+  G  +  RD+K    L  A     + +V+ L+  GA +
Sbjct: 1742 ETPLIIASRMGHLAVVSELLKVPGIDVNERDEKLRPALYFACMGNDIELVKQLVRYGARV 1563

Query: 1139 EAQSERTKDTPLSLACSGGRQEVVELLLARGANKEHRNVSDYTPLSLAASGGYVNIIKIL 1198
             A S  T  TP    C  G   +   LL  GANKE R V   TPL +A       +  +L
Sbjct: 1562 NAYSTETWWTPFHACCKRGDPRIALYLLRHGANKESRTVDGKTPLVVACKNDKAEVALLL 1383

Query: 1199 LNAGAEINSRTGSKLGISPLMLAAMNGHTAAVKLLLDMGSDINAQIETNRNTALTLACFQ 1258
            + +GA +N                             +  DI A      NT +  AC +
Sbjct: 1382 IRSGANVN-----------------------------VSCDITA------NTPVHFACQR 1308

Query: 1259 GRTEVVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDK-GADVNAPPVPSSRD 1317
               E++  L+   A+V+     G T L  A+  G+ +    LLD   A+VNA  +    +
Sbjct: 1307 PNIELLKRLVLHGADVDKPNAKGHTALHVASVRGFKQHVIYLLDFCDAEVNAATLKG--N 1134

Query: 1318 TALTIAADKGHYKFCELLIGKGAHIDVRNKKGNTP 1352
             AL IA    H    ELL+ KGA+   RN++G TP
Sbjct: 1133 NALHIACRGKHADLVELLLHKGANPAQRNQRGWTP 1029

 Score = 83.2 bits (204), Expect = 1e-15,   Method: Compositional matrix adjust.
 Identities = 79/280 (28%), Positives = 121/280 (43%), Gaps = 2/280 (0%)
 Frame = -1

Query: 1114 TPLILAATAGHVGVV-EILLDNGADIEAQSERTKDTPLSLACSGGRQEVVELLLARGAN- 1171
            TPLI+A+  GH+ VV E+L   G D+  + E+ +   L  AC G   E+V+ L+  GA  
Sbjct: 1739 TPLIIASRMGHLAVVSELLKVPGIDVNERDEKLRPA-LYFACMGNDIELVKQLVRYGARV 1563

Query: 1172 KEHRNVSDYTPLSLAASGGYVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHTAAVK 1231
              +   + +TP       G   I   LL  GA   SRT    G +PL++A  N       
Sbjct: 1562 NAYSTETWWTPFHACCKRGDPRIALYLLRHGANKESRTVD--GKTPLVVACKNDKAEVAL 1389

Query: 1232 LLLDMGSDINAQIETNRNTALTLACFQGRTEVVSLLLDRKANVEHRAKTGLTPLMEAASG 1291
            LL+  G+++N   +   NT +  AC +   E++  L+   A+V+     G T L  A+  
Sbjct: 1388 LLIRSGANVNVSCDITANTPVHFACQRPNIELLKRLVLHGADVDKPNAKGHTALHVASVR 1209

Query: 1292 GYAEVGRVLLDKGADVNAPPVPSSRDTALTIAADKGHYKFCELLIGKGAHIDVRNKKGNT 1351
            G+ +    LLD                            FC+      A ++    KGN 
Sbjct: 1208 GFKQHVIYLLD----------------------------FCD------AEVNAATLKGNN 1131

Query: 1352 PLWLAANGGHLDVVQLLVQATADVDAADNRKITPLMAAFR 1391
             L +A  G H D+V+LL+   A+    + R  TP  +A R
Sbjct: 1130 ALHIACRGKHADLVELLLHKGANPAQRNQRGWTPRNSAGR 1011

 Score = 81.6 bits (200), Expect = 4e-15,   Method: Compositional matrix adjust.
 Identities = 64/220 (29%), Positives = 103/220 (46%), Gaps = 2/220 (0%)
 Frame = -1

Query: 299  TPLMAAANGGHVKIV-KLLLAHKADVNAQSSTGNTALTYACAGGYVDVVKVLLESGASIE 357
            TPL+ A+  GH+ +V +LL     DVN +      AL +AC G  +++VK L+  G    
Sbjct: 1739 TPLIIASRMGHLAVVSELLKVPGIDVNERDEKLRPALYFACMGNDIELVKQLVRYG---- 1572

Query: 358  DHNENGHTPLMEAGSAGHVEVARLLLENGAGINTHSNEFKESALTLACYKGHLEMVRFLL 417
                                         A +N +S E   +     C +G   +  +LL
Sbjct: 1571 -----------------------------ARVNAYSTETWWTPFHACCKRGDPRIALYLL 1479

Query: 418  EAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPAD-SFESPLTLAACGGHV 476
              GA++E +T +  T L+ AC +   EVA LL+ SGA VN+  D +  +P+  A    ++
Sbjct: 1478 RHGANKESRTVDGKTPLVVACKNDKAEVALLLIRSGANVNVSCDITANTPVHFACQRPNI 1299

Query: 477  ELAALLIERGASLEEVNDEGYTPLMEAAREGHEEMVALLL 516
            EL   L+  GA +++ N +G+T L  A+  G ++ V  LL
Sbjct: 1298 ELLKRLVLHGADVDKPNAKGHTALHVASVRGFKQHVIYLL 1179

 Score = 79.7 bits (195), Expect = 1e-14,   Method: Compositional matrix adjust.
 Identities = 72/239 (30%), Positives = 120/239 (50%), Gaps = 7/239 (2%)
 Frame = -1

Query: 464  ESPLTLAACGGHVELAALLIER-GASLEEVNDEGYTPLMEAAREGHE-EMVALLLGQGAN 521
            E+PL +A+  GH+ + + L++  G  + E  DE   P +  A  G++ E+V  L+  GA 
Sbjct: 1742 ETPLIIASRMGHLAVVSELLKVPGIDVNE-RDEKLRPALYFACMGNDIELVKQLVRYGAR 1566

Query: 522  INXXXXXXXXXXXXXXCCGGFLEVADFLIKAGADIE---LGCSTPLMEAAQEGHLELVKY 578
            +N              C  G   +A +L++ GA+ E   +   TPL+ A +    E+   
Sbjct: 1565 VNAYSTETWWTPFHACCKRGDPRIALYLLRHGANKESRTVDGKTPLVVACKNDKAEVALL 1386

Query: 579  LLAAGANVHATT-ATGDTALTYACENGHTDVADVLLQAGADLEHESEGGRTPLMKAARAG 637
            L+ +GANV+ +   T +T + +AC+  + ++   L+  GAD++  +  G T L  A+  G
Sbjct: 1385 LIRSGANVNVSCDITANTPVHFACQRPNIELLKRLVLHGADVDKPNAKGHTALHVASVRG 1206

Query: 638  HVCTVQFLISK-GANVNRTTANNDHTVLSLACAGGHLAVVELLLAHGADPTHRLKDGST 695
                V +L+    A VN  T   ++  L +AC G H  +VELLL  GA+P  R + G T
Sbjct: 1205 FKQHVIYLLDFCDAEVNAATLKGNNA-LHIACRGKHADLVELLLHKGANPAQRNQRGWT 1032

 Score = 74.3 bits (181), Expect = 6e-13,   Method: Compositional matrix adjust.
 Identities = 68/227 (29%), Positives = 105/227 (46%), Gaps = 3/227 (1%)
 Frame = -1

Query: 1181 TPLSLAASGGYVNIIKILLNA-GAEINSRTGSKLGISP-LMLAAMNGHTAAVKLLLDMGS 1238
            TPL +A+  G++ ++  LL   G ++N R      + P L  A M      VK L+  G+
Sbjct: 1739 TPLIIASRMGHLAVVSELLKVPGIDVNERDEK---LRPALYFACMGNDIELVKQLVRYGA 1569

Query: 1239 DINAQIETNRNTALTLACFQGRTEVVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEVGR 1298
             +NA       T     C +G   +   LL   AN E R   G TPL+ A     AEV  
Sbjct: 1568 RVNAYSTETWWTPFHACCKRGDPRIALYLLRHGANKESRTVDGKTPLVVACKNDKAEVAL 1389

Query: 1299 VLLDKGADVNAPPVPSSRDTALTIAADKGHYKFCELLIGKGAHIDVRNKKGNTPLWLAA- 1357
            +L+  GA+VN      + +T +  A  + + +  + L+  GA +D  N KG+T L +A+ 
Sbjct: 1388 LLIRSGANVNV-SCDITANTPVHFACQRPNIELLKRLVLHGADVDKPNAKGHTALHVASV 1212

Query: 1358 NGGHLDVVQLLVQATADVDAADNRKITPLMAAFRKGHVKVVRYLVKE 1404
             G    V+ LL    A+V+AA  +    L  A R  H  +V  L+ +
Sbjct: 1211 RGFKQHVIYLLDFCDAEVNAATLKGNNALHIACRGKHADLVELLLHK 1071

 Score = 67.8 bits (164), Expect = 5e-11,   Method: Compositional matrix adjust.
 Identities = 52/153 (33%), Positives = 75/153 (49%), Gaps = 1/153 (0%)
 Frame = -1

Query: 564  LMEAAQEGHLELVKYLLAAGANVHA-TTATGDTALTYACENGHTDVADVLLQAGADLEHE 622
            L  A     +ELVK L+  GA V+A +T T  T     C+ G   +A  LL+ GA+ E  
Sbjct: 1631 LYFACMGNDIELVKQLVRYGARVNAYSTETWWTPFHACCKRGDPRIALYLLRHGANKESR 1452

Query: 623  SEGGRTPLMKAARAGHVCTVQFLISKGANVNRTTANNDHTVLSLACAGGHLAVVELLLAH 682
            +  G+TPL+ A +         LI  GANVN +     +T +  AC   ++ +++ L+ H
Sbjct: 1451 TVDGKTPLVVACKNDKAEVALLLIRSGANVNVSCDITANTPVHFACQRPNIELLKRLVLH 1272

Query: 683  GADPTHRLKDGSTMLIEAAKGGHTSVVCYLLDY 715
            GAD       G T L  A+  G    V YLLD+
Sbjct: 1271 GADVDKPNAKGHTALHVASVRGFKQHVIYLLDF 1173

 Score = 66.6 bits (161), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 58/205 (28%), Positives = 97/205 (47%), Gaps = 4/205 (1%)
 Frame = -1

Query: 1071 IDAQTESNHDTALTLACAGGHEELVQTLLERGASIEHRDKKGFTPLILAATAGHVGVVEI 1130
            ++A +     T     C  G   +   LL  GA+ E R   G TPL++A       V  +
Sbjct: 1565 VNAYSTETWWTPFHACCKRGDPRIALYLLRHGANKESRTVDGKTPLVVACKNDKAEVALL 1386

Query: 1131 LLDNGADIEAQSERTKDTPLSLACSGGRQEVVELLLARGANKEHRNVSDYTPLSLAASGG 1190
            L+ +GA++    + T +TP+  AC     E+++ L+  GA+ +  N   +T L +A+  G
Sbjct: 1385 LIRSGANVNVSCDITANTPVHFACQRPNIELLKRLVLHGADVDKPNAKGHTALHVASVRG 1206

Query: 1191 YV-NIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHTAAVKLLLDMGSD---INAQIET 1246
            +  ++I +L    AE+N+ T    G + L +A    H   V+LLL  G++    N +  T
Sbjct: 1205 FKQHVIYLLDFCDAEVNAATLK--GNNALHIACRGKHADLVELLLHKGANPAQRNQRGWT 1032

Query: 1247 NRNTALTLACFQGRTEVVSLLLDRK 1271
             RN+A       GR   V  +LD +
Sbjct: 1031 PRNSA-------GRCXEVLDILDSR 978

 Score = 57.4 bits (137), Expect = 7e-08,   Method: Compositional matrix adjust.
 Identities = 55/204 (26%), Positives = 81/204 (39%), Gaps = 37/204 (18%)
 Frame = -1

Query: 210  EAAAALTRMRAESTANAGQSDNRSLAEACSEGDVNAVRKLLIEGRSVNEHTEEGESLLCL 269
            E    L R  A   A + ++        C  GD      LL  G +    T +G++ L +
Sbjct: 1601 ELVKQLVRYGARVNAYSTETWWTPFHACCKRGDPRIALYLLRHGANKESRTVDGKTPLVV 1422

Query: 270  ACSAGYYELAQVLLAMHANVEDRGIKGDIT---PLMAAANGGHVKIVKLLLAHKADV--- 323
            AC     E+A +L+   ANV    +  DIT   P+  A    +++++K L+ H ADV   
Sbjct: 1421 ACKNDKAEVALLLIRSGANVN---VSCDITANTPVHFACQRPNIELLKRLVLHGADVDKP 1251

Query: 324  -------------------------------NAQSSTGNTALTYACAGGYVDVVKVLLES 352
                                           NA +  GN AL  AC G + D+V++LL  
Sbjct: 1250 NAKGHTALHVASVRGFKQHVIYLLDFCDAEVNAATLKGNNALHIACRGKHADLVELLLHK 1071

Query: 353  GASIEDHNENGHTPLMEAGSAGHV 376
            GA+    N+ G TP   AG    V
Sbjct: 1070 GANPAQRNQRGWTPRNSAGRCXEV 999
>13462
          Length = 1388

 Score = 92.4 bits (228), Expect = 2e-18,   Method: Compositional matrix adjust.
 Identities = 88/308 (28%), Positives = 138/308 (44%), Gaps = 36/308 (11%)
 Frame = +3

Query: 252 EGRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGIKGDITPLMAAAN--GGH 309
           +G  VN     G +LLC+AC     +L  VLL   A  +   +  +  PL  A++   G+
Sbjct: 42  QGDLVNGLCGNGLTLLCVACKLNRADLVPVLLQRGALPDLPSLYLNKRPLHYASHHSNGN 221

Query: 310 VKIVKLLLAHKADVNAQSSTGNTALTYACAGGYVDVVKVLLESGASIEDHNENGHTPLME 369
           + IV +LLA+ A  N Q   GNTAL  AC+   VDVV++LLE G  +   + +  TPL+ 
Sbjct: 222 LGIVSMLLAYGAQPNVQDEDGNTALHLACSESNVDVVRLLLEWGGDVAVADIDNETPLVR 401

Query: 370 AGSAGHVEVARLLLENGAGIN-THSNEFK-----------------------ESALTLAC 405
           A  A  VE+  LLL  G+  N +H    +                        + L+ A 
Sbjct: 402 ACLANSVELVDLLLHAGSDPNHSHGRPLEIVVRAPSLESLKLLIGAGAQVTGNTYLSFAS 581

Query: 406 YKGHLEMVRFLLEAGADQEHKTDEMHTALMEACMDGHV--EVARLLLDSGAQVNMPADSF 463
              +L+M++ L   G D         TAL  AC+      +  RLLL  G+  N+   + 
Sbjct: 582 EHNYLDMMKVLHNYGVDVNGTGRLGLTALHHACISQEATHDAVRLLLLWGSNPNLVTGTG 761

Query: 464 ESPLTLAACGGHVELAALLIERGASLEEVNDEGYTPLMEAARE--------GHEEMVALL 515
           ++PL  A     V    LL+  GA + +++    +PL+ A            + +++ LL
Sbjct: 762 DTPLHFACQTFAVSKVRLLLMYGADVNQIDGTHTSPLIAALTTRRQPQNDASYLDLIRLL 941

Query: 516 LGQGANIN 523
           L  GA ++
Sbjct: 942 LAAGARLS 965

 Score = 82.4 bits (202), Expect = 2e-15,   Method: Compositional matrix adjust.
 Identities = 88/308 (28%), Positives = 136/308 (44%), Gaps = 16/308 (5%)
 Frame = +3

Query: 362 NGHTPLMEAGSAGHVEVARLLLENGAGINTHSNEFKESALTLACY--KGHLEMVRFLLEA 419
           NG T L  A      ++  +LL+ GA  +  S    +  L  A +   G+L +V  LL  
Sbjct: 72  NGLTLLCVACKLNRADLVPVLLQRGALPDLPSLYLNKRPLHYASHHSNGNLGIVSMLLAY 251

Query: 420 GADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHVELA 479
           GA    + ++ +TAL  AC + +V+V RLLL+ G  V +     E+PL  A     VEL 
Sbjct: 252 GAQPNVQDEDGNTALHLACSESNVDVVRLLLEWGGDVAVADIDNETPLVRACLANSVELV 431

Query: 480 ALLIERGASLEEVNDEGYTPLMEAAREGHEEMVALLLGQGANINXXXXXXXXXXXXXXCC 539
            LL+  G+   + N     PL    R    E + LL+G GA +                 
Sbjct: 432 DLLLHAGS---DPNHSHGRPLEIVVRAPSLESLKLLIGAGAQVTGNTYLSFASEH----- 587

Query: 540 GGFLEVADFLIKAGADI----ELGCSTPLMEA--AQEGHLELVKYLLAAGANVHATTATG 593
             +L++   L   G D+     LG  T L  A  +QE   + V+ LL  G+N +  T TG
Sbjct: 588 -NYLDMMKVLHNYGVDVNGTGRLGL-TALHHACISQEATHDAVRLLLLWGSNPNLVTGTG 761

Query: 594 DTALTYACENGHTDVADVLLQAGADLEHESEGGRTPLMKAAR--------AGHVCTVQFL 645
           DT L +AC+        +LL  GAD+        +PL+ A          A ++  ++ L
Sbjct: 762 DTPLHFACQTFAVSKVRLLLMYGADVNQIDGTHTSPLIAALTTRRQPQNDASYLDLIRLL 941

Query: 646 ISKGANVN 653
           ++ GA ++
Sbjct: 942 LAAGARLS 965

 Score = 80.5 bits (197), Expect = 7e-15,   Method: Compositional matrix adjust.
 Identities = 91/327 (27%), Positives = 151/327 (46%), Gaps = 16/327 (4%)
 Frame = +3

Query: 1081 TALTLACAGGHEELVQTLLERGASIE----HRDKKGFTPLILAA--TAGHVGVVEILLDN 1134
            T L +AC     +LV  LL+RGA  +    + +K+   PL  A+  + G++G+V +LL  
Sbjct: 81   TLLCVACKLNRADLVPVLLQRGALPDLPSLYLNKR---PLHYASHHSNGNLGIVSMLLAY 251

Query: 1135 GADIEAQSERTKDTPLSLACSGGRQEVVELLLARGANKEHRNVSDYTPLSLAASGGYVNI 1194
            GA    Q E   +T L LACS    +VV LLL  G +    ++ + TPL  A     V +
Sbjct: 252  GAQPNVQDE-DGNTALHLACSESNVDVVRLLLEWGGDVAVADIDNETPLVRACLANSVEL 428

Query: 1195 IKILLNAGAEINSRTGSKLGISPLMLAAMNGHTAAVKLLLDMGSDINAQIETNRNTALTL 1254
            + +LL+AG++ N   G      PL +        ++KLL+  G+ +        NT L+ 
Sbjct: 429  VDLLLHAGSDPNHSHG-----RPLEIVVRAPSLESLKLLIGAGAQVTG------NTYLSF 575

Query: 1255 ACFQGRTEVVSLLLDRKANVEHRAKTGLTPLMEAASGGYA--EVGRVLLDKGADVNAPPV 1312
            A      +++ +L +   +V    + GLT L  A     A  +  R+LL  G++ N   V
Sbjct: 576  ASEHNYLDMMKVLHNYGVDVNGTGRLGLTALHHACISQEATHDAVRLLLLWGSNPNL--V 749

Query: 1313 PSSRDTALTIAADKGHYKFCELLIGKGAHIDVRNKKGNTPLWLAA--------NGGHLDV 1364
              + DT L  A          LL+  GA ++  +    +PL  A         +  +LD+
Sbjct: 750  TGTGDTPLHFACQTFAVSKVRLLLMYGADVNQIDGTHTSPLIAALTTRRQPQNDASYLDL 929

Query: 1365 VQLLVQATADVDAADNRKITPLMAAFR 1391
            ++LL+ A A + +A   +I  L+   +
Sbjct: 930  IRLLLAAGARLSSAVLERIKVLIVYLQ 1010

 Score = 80.1 bits (196), Expect = 1e-14,   Method: Compositional matrix adjust.
 Identities = 77/244 (31%), Positives = 122/244 (50%), Gaps = 10/244 (4%)
 Frame = +3

Query: 1076 ESNHDTALTLACAGGHEELVQTLLERGASIEHRDKKGFTPLILAATAGHVGVVEILLDNG 1135
            + + +TAL LAC+  + ++V+ LLE G  +   D    TPL+ A  A  V +V++LL  G
Sbjct: 273  DEDGNTALHLACSESNVDVVRLLLEWGGDVAVADIDNETPLVRACLANSVELVDLLLHAG 452

Query: 1136 ADIEAQSERTKDTPLSLACSGGRQEVVELLLARGANKEHRNVSDYTPLSLAASGGYVNII 1195
            +D      R    PL +       E ++LL+  GA      V+  T LS A+   Y++++
Sbjct: 453  SDPNHSHGR----PLEIVVRAPSLESLKLLIGAGA-----QVTGNTYLSFASEHNYLDMM 605

Query: 1196 KILLNAGAEINSRTGSKLGISPLMLAAMNGHTA--AVKLLLDMGSDINAQIETNRNTALT 1253
            K+L N G ++N  TG +LG++ L  A ++      AV+LLL  GS+ N    T  +T L 
Sbjct: 606  KVLHNYGVDVNG-TG-RLGLTALHHACISQEATHDAVRLLLLWGSNPNLVTGTG-DTPLH 776

Query: 1254 LACFQGRTEVVSLLLDRKANVEHRAKTGLTPLMEAAS--------GGYAEVGRVLLDKGA 1305
             AC       V LLL   A+V     T  +PL+ A +          Y ++ R+LL  GA
Sbjct: 777  FACQTFAVSKVRLLLMYGADVNQIDGTHTSPLIAALTTRRQPQNDASYLDLIRLLLAAGA 956

Query: 1306 DVNA 1309
             +++
Sbjct: 957  RLSS 968

 Score = 69.3 bits (168), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 81/287 (28%), Positives = 123/287 (42%), Gaps = 7/287 (2%)
 Frame = +3

Query: 1111 KGFTPLILAATAGHVGVVEILLDNGADIEAQSERTKDTPLSLAC--SGGRQEVVELLLAR 1168
             G T L +A       +V +LL  GA  +  S      PL  A   S G   +V +LLA 
Sbjct: 72   NGLTLLCVACKLNRADLVPVLLQRGALPDLPSLYLNKRPLHYASHHSNGNLGIVSMLLAY 251

Query: 1169 GANKEHRNVSDYTPLSLAASGGYVNIIKILLNAG-----AEINSRTGSKLGISPLMLAAM 1223
            GA    ++    T L LA S   V+++++LL  G     A+I++ T       PL+ A +
Sbjct: 252  GAQPNVQDEDGNTALHLACSESNVDVVRLLLEWGGDVAVADIDNET-------PLVRACL 410

Query: 1224 NGHTAAVKLLLDMGSDINAQIETNRNTALTLACFQGRTEVVSLLLDRKANVEHRAKTGLT 1283
                  V LLL  GSD N     +    L +       E + LL+   A V     TG T
Sbjct: 411  ANSVELVDLLLHAGSDPNH----SHGRPLEIVVRAPSLESLKLLIGAGAQV-----TGNT 563

Query: 1284 PLMEAASGGYAEVGRVLLDKGADVNAPPVPSSRDTALTIAADKGHYKFCELLIGKGAHID 1343
             L  A+   Y ++ +VL + G DVN               + +  +    LL+  G++ +
Sbjct: 564  YLSFASEHNYLDMMKVLHNYGVDVNGTGRLGLTALHHACISQEATHDAVRLLLLWGSNPN 743

Query: 1344 VRNKKGNTPLWLAANGGHLDVVQLLVQATADVDAADNRKITPLMAAF 1390
            +    G+TPL  A     +  V+LL+   ADV+  D    +PL+AA 
Sbjct: 744  LVTGTGDTPLHFACQTFAVSKVRLLLMYGADVNQIDGTHTSPLIAAL 884

 Score = 65.1 bits (157), Expect = 4e-10,   Method: Compositional matrix adjust.
 Identities = 73/256 (28%), Positives = 112/256 (43%), Gaps = 37/256 (14%)
 Frame = +3

Query: 239 SEGDVNAVRKLLIEGRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGIKGDI 298
           S G++  V  LL  G   N   E+G + L LACS    ++ ++LL    +V    I  + 
Sbjct: 210 SNGNLGIVSMLLAYGAQPNVQDEDGNTALHLACSESNVDVVRLLLEWGGDVAVADIDNE- 386

Query: 299 TPLMAAANGGHVKIVKLLLAHKADVN-------------------------AQSSTGNTA 333
           TPL+ A     V++V LLL   +D N                             TGNT 
Sbjct: 387 TPLVRACLANSVELVDLLLHAGSDPNHSHGRPLEIVVRAPSLESLKLLIGAGAQVTGNTY 566

Query: 334 LTYACAGGYVDVVKVLLESGASIEDHNENGHTPLMEAG---SAGHVEVARLLLENGAGIN 390
           L++A    Y+D++KVL   G  +      G T L  A     A H +  RLLL  G+  N
Sbjct: 567 LSFASEHNYLDMMKVLHNYGVDVNGTGRLGLTALHHACISQEATH-DAVRLLLLWGSNPN 743

Query: 391 THSNEFKESALTLACYKGHLEMVRFLLEAGADQEHKTDEMHTALMEACMD---------G 441
             +    ++ L  AC    +  VR LL  GAD  ++ D  HT+ + A +           
Sbjct: 744 LVTGT-GDTPLHFACQTFAVSKVRLLLMYGAD-VNQIDGTHTSPLIAALTTRRQPQNDAS 917

Query: 442 HVEVARLLLDSGAQVN 457
           ++++ RLLL +GA+++
Sbjct: 918 YLDLIRLLLAAGARLS 965

 Score = 50.4 bits (119), Expect = 9e-06,   Method: Compositional matrix adjust.
 Identities = 42/126 (33%), Positives = 63/126 (50%), Gaps = 4/126 (3%)
 Frame = +3

Query: 1281 GLTPLMEAASGGYAEVGRVLLDKGADVNAPPVPS----SRDTALTIAADKGHYKFCELLI 1336
            GLT L  A     A++  VLL +GA    P +PS     R          G+     +L+
Sbjct: 75   GLTLLCVACKLNRADLVPVLLQRGA---LPDLPSLYLNKRPLHYASHHSNGNLGIVSMLL 245

Query: 1337 GKGAHIDVRNKKGNTPLWLAANGGHLDVVQLLVQATADVDAADNRKITPLMAAFRKGHVK 1396
              GA  +V+++ GNT L LA +  ++DVV+LL++   DV  AD    TPL+ A     V+
Sbjct: 246  AYGAQPNVQDEDGNTALHLACSESNVDVVRLLLEWGGDVAVADIDNETPLVRACLANSVE 425

Query: 1397 VVRYLV 1402
            +V  L+
Sbjct: 426  LVDLLL 443

 Score = 49.7 bits (117), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 46/155 (29%), Positives = 72/155 (46%), Gaps = 2/155 (1%)
 Frame = +3

Query: 563 PLMEAAQE--GHLELVKYLLAAGANVHATTATGDTALTYACENGHTDVADVLLQAGADLE 620
           PL  A+    G+L +V  LLA GA  +     G+TAL  AC   + DV  +LL+ G D+ 
Sbjct: 186 PLHYASHHSNGNLGIVSMLLAYGAQPNVQDEDGNTALHLACSESNVDVVRLLLEWGGDVA 365

Query: 621 HESEGGRTPLMKAARAGHVCTVQFLISKGANVNRTTANNDHTVLSLACAGGHLAVVELLL 680
                  TPL++A  A  V  V  L+  G++ N +        L +      L  ++LL+
Sbjct: 366 VADIDNETPLVRACLANSVELVDLLLHAGSDPNHSHGRP----LEIVVRAPSLESLKLLI 533

Query: 681 AHGADPTHRLKDGSTMLIEAAKGGHTSVVCYLLDY 715
             GA  T     G+T L  A++  +  ++  L +Y
Sbjct: 534 GAGAQVT-----GNTYLSFASEHNYLDMMKVLHNY 623

 Score = 43.1 bits (100), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 48/145 (33%), Positives = 64/145 (44%), Gaps = 4/145 (2%)
 Frame = +3

Query: 573 LELVKYLLAAGANVHATTATGDTALTYACENGHTDVADVLLQAGA--DLEHESEGGRTPL 630
           L LV +    G  V+     G T L  AC+    D+  VLLQ GA  DL       R PL
Sbjct: 15  LMLVSWDGGQGDLVNGLCGNGLTLLCVACKLNRADLVPVLLQRGALPDLPSLYLNKR-PL 191

Query: 631 MKAARA--GHVCTVQFLISKGANVNRTTANNDHTVLSLACAGGHLAVVELLLAHGADPTH 688
             A+    G++  V  L++ GA  N     + +T L LAC+  ++ VV LLL  G D   
Sbjct: 192 HYASHHSNGNLGIVSMLLAYGAQPN-VQDEDGNTALHLACSESNVDVVRLLLEWGGDVAV 368

Query: 689 RLKDGSTMLIEAAKGGHTSVVCYLL 713
              D  T L+ A       +V  LL
Sbjct: 369 ADIDNETPLVRACLANSVELVDLLL 443

 Score = 33.9 bits (76), Expect = 0.90,   Method: Compositional matrix adjust.
 Identities = 47/188 (25%), Positives = 81/188 (43%), Gaps = 3/188 (1%)
 Frame = +3

Query: 1247 NRNTALTLACFQGRTEVVSLLLDRKANVEH-RAKTGLTPLMEAA--SGGYAEVGRVLLDK 1303
            N  T L +AC   R ++V +LL R A  +         PL  A+  S G   +  +LL  
Sbjct: 72   NGLTLLCVACKLNRADLVPVLLQRGALPDLPSLYLNKRPLHYASHHSNGNLGIVSMLLAY 251

Query: 1304 GADVNAPPVPSSRDTALTIAADKGHYKFCELLIGKGAHIDVRNKKGNTPLWLAANGGHLD 1363
            GA  N        +TAL +A  + +     LL+  G  + V +    TPL  A     ++
Sbjct: 252  GAQPNVQD--EDGNTALHLACSESNVDVVRLLLEWGGDVAVADIDNETPLVRACLANSVE 425

Query: 1364 VVQLLVQATADVDAADNRKITPLMAAFRKGHVKVVRYLVKEVNQFPSDSECMRYIATITD 1423
            +V LL+ A +D + +  R   PL    R   ++ ++ L+    Q   ++  + + +    
Sbjct: 426  LVDLLLHAGSDPNHSHGR---PLEIVVRAPSLESLKLLIGAGAQVTGNTY-LSFASEHNY 593

Query: 1424 KEMLKKCH 1431
             +M+K  H
Sbjct: 594  LDMMKVLH 617
>05924
          Length = 704

 Score = 90.1 bits (222), Expect = 1e-17,   Method: Composition-based stats.
 Identities = 65/201 (32%), Positives = 104/201 (51%)
 Frame = +1

Query: 1128 VEILLDNGADIEAQSERTKDTPLSLACSGGRQEVVELLLARGANKEHRNVSDYTPLSLAA 1187
            V+ L+  G D+ A+      T L  A S   +++V++L+  GAN    N    T L LA 
Sbjct: 13   VQRLVKGGVDVNARF-WYDSTLLHEAVSMASEDLVQMLIKAGANANSTNQDGRTALHLAC 189

Query: 1188 SGGYVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHTAAVKLLLDMGSDINAQIETN 1247
             GGY NI++IL+ AG ++N RT    G + L +A   GHT  V  L++ G+D+N   ++ 
Sbjct: 190  RGGYTNIVQILIAAGTDVNRRTVD--GKTCLHVAVWRGHTEVVVKLVNAGADVNIP-DSV 360

Query: 1248 RNTALTLACFQGRTEVVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADV 1307
              + L  A     T ++++L++  A V +R K+  TPL  A   G+  V R LL +GA+ 
Sbjct: 361  GCSPLYWAARSNYTAILTVLVNAGAKVNYRVKSKWTPLHAALHLGHMGVVRYLLLQGAET 540

Query: 1308 NAPPVPSSRDTALTIAADKGH 1328
            N   +     T +++  D  H
Sbjct: 541  N---ITVQDKTVVSLLMDNEH 594

 Score = 87.4 bits (215), Expect = 7e-17,   Method: Composition-based stats.
 Identities = 58/174 (33%), Positives = 90/174 (51%)
 Frame = +1

Query: 1229 AVKLLLDMGSDINAQIETNRNTALTLACFQGRTEVVSLLLDRKANVEHRAKTGLTPLMEA 1288
            AV+ L+  G D+NA+   + +T L  A      ++V +L+   AN     + G T L  A
Sbjct: 10   AVQRLVKGGVDVNARFWYD-STLLHEAVSMASEDLVQMLIKAGANANSTNQDGRTALHLA 186

Query: 1289 ASGGYAEVGRVLLDKGADVNAPPVPSSRDTALTIAADKGHYKFCELLIGKGAHIDVRNKK 1348
              GGY  + ++L+  G DVN   V     T L +A  +GH +    L+  GA +++ +  
Sbjct: 187  CRGGYTNIVQILIAAGTDVNRRTVDGK--TCLHVAVWRGHTEVVVKLVNAGADVNIPDSV 360

Query: 1349 GNTPLWLAANGGHLDVVQLLVQATADVDAADNRKITPLMAAFRKGHVKVVRYLV 1402
            G +PL+ AA   +  ++ +LV A A V+     K TPL AA   GH+ VVRYL+
Sbjct: 361  GCSPLYWAARSNYTAILTVLVNAGAKVNYRVKSKWTPLHAALHLGHMGVVRYLL 522

 Score = 85.9 bits (211), Expect = 2e-16,   Method: Composition-based stats.
 Identities = 59/178 (33%), Positives = 90/178 (50%)
 Frame = +1

Query: 346 VKVLLESGASIEDHNENGHTPLMEAGSAGHVEVARLLLENGAGINTHSNEFKESALTLAC 405
           V+ L++ G  +        T L EA S    ++ ++L++ GA  N+ +N+   +AL LAC
Sbjct: 13  VQRLVKGGVDVNARFWYDSTLLHEAVSMASEDLVQMLIKAGANANS-TNQDGRTALHLAC 189

Query: 406 YKGHLEMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFES 465
             G+  +V+ L+ AG D   +T +  T L  A   GH EV   L+++GA VN+P     S
Sbjct: 190 RGGYTNIVQILIAAGTDVNRRTVDGKTCLHVAVWRGHTEVVVKLVNAGADVNIPDSVGCS 369

Query: 466 PLTLAACGGHVELAALLIERGASLEEVNDEGYTPLMEAAREGHEEMVALLLGQGANIN 523
           PL  AA   +  +  +L+  GA +       +TPL  A   GH  +V  LL QGA  N
Sbjct: 370 PLYWAARSNYTAILTVLVNAGAKVNYRVKSKWTPLHAALHLGHMGVVRYLLLQGAETN 543

 Score = 85.5 bits (210), Expect = 3e-16,   Method: Composition-based stats.
 Identities = 59/180 (32%), Positives = 88/180 (48%), Gaps = 3/180 (1%)
 Frame = +1

Query: 498 TPLMEAAREGHEEMVALLLGQGANINXXXXXXXXXXXXXXCCGGFLEVADFLIKAGADIE 557
           T L EA     E++V +L+  GAN N              C GG+  +   LI AG D+ 
Sbjct: 70  TLLHEAVSMASEDLVQMLIKAGANANSTNQDGRTALHLA-CRGGYTNIVQILIAAGTDVN 246

Query: 558 ---LGCSTPLMEAAQEGHLELVKYLLAAGANVHATTATGDTALTYACENGHTDVADVLLQ 614
              +   T L  A   GH E+V  L+ AGA+V+   + G + L +A  + +T +  VL+ 
Sbjct: 247 RRTVDGKTCLHVAVWRGHTEVVVKLVNAGADVNIPDSVGCSPLYWAARSNYTAILTVLVN 426

Query: 615 AGADLEHESEGGRTPLMKAARAGHVCTVQFLISKGANVNRTTANNDHTVLSLACAGGHLA 674
           AGA + +  +   TPL  A   GH+  V++L+ +GA  N T    D TV+SL     HL+
Sbjct: 427 AGAKVNYRVKSKWTPLHAALHLGHMGVVRYLLLQGAETNITV--QDKTVVSLLMDNEHLS 600

 Score = 85.1 bits (209), Expect = 3e-16,   Method: Composition-based stats.
 Identities = 55/161 (34%), Positives = 81/161 (50%)
 Frame = +1

Query: 230 DNRSLAEACSEGDVNAVRKLLIEGRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANV 289
           D+  L EA S    + V+ L+  G + N   ++G + L LAC  GY  + Q+L+A   +V
Sbjct: 64  DSTLLHEAVSMASEDLVQMLIKAGANANSTNQDGRTALHLACRGGYTNIVQILIAAGTDV 243

Query: 290 EDRGIKGDITPLMAAANGGHVKIVKLLLAHKADVNAQSSTGNTALTYACAGGYVDVVKVL 349
             R + G  T L  A   GH ++V  L+   ADVN   S G + L +A    Y  ++ VL
Sbjct: 244 NRRTVDGK-TCLHVAVWRGHTEVVVKLVNAGADVNIPDSVGCSPLYWAARSNYTAILTVL 420

Query: 350 LESGASIEDHNENGHTPLMEAGSAGHVEVARLLLENGAGIN 390
           + +GA +    ++  TPL  A   GH+ V R LL  GA  N
Sbjct: 421 VNAGAKVNYRVKSKWTPLHAALHLGHMGVVRYLLLQGAETN 543

 Score = 84.0 bits (206), Expect = 7e-16,   Method: Composition-based stats.
 Identities = 59/168 (35%), Positives = 86/168 (51%), Gaps = 3/168 (1%)
 Frame = +1

Query: 549 LIKAGADIELGC---STPLMEAAQEGHLELVKYLLAAGANVHATTATGDTALTYACENGH 605
           L+K G D+       ST L EA      +LV+ L+ AGAN ++T   G TAL  AC  G+
Sbjct: 22  LVKGGVDVNARFWYDSTLLHEAVSMASEDLVQMLIKAGANANSTNQDGRTALHLACRGGY 201

Query: 606 TDVADVLLQAGADLEHESEGGRTPLMKAARAGHVCTVQFLISKGANVNRTTANNDHTVLS 665
           T++  +L+ AG D+   +  G+T L  A   GH   V  L++ GA+VN    +   + L 
Sbjct: 202 TNIVQILIAAGTDVNRRTVDGKTCLHVAVWRGHTEVVVKLVNAGADVN-IPDSVGCSPLY 378

Query: 666 LACAGGHLAVVELLLAHGADPTHRLKDGSTMLIEAAKGGHTSVVCYLL 713
            A    + A++ +L+  GA   +R+K   T L  A   GH  VV YLL
Sbjct: 379 WAARSNYTAILTVLVNAGAKVNYRVKSKWTPLHAALHLGHMGVVRYLL 522

 Score = 77.4 bits (189), Expect = 7e-14,   Method: Composition-based stats.
 Identities = 64/205 (31%), Positives = 92/205 (44%)
 Frame = +1

Query: 1075 TESNHDTALTLACAGGHEELVQTLLERGASIEHRDKKGFTPLILAATAGHVGVVEILLDN 1134
            T  +  TAL LAC GG+  +VQ L+  G  +  R   G T L +A   GH  VV  L++ 
Sbjct: 151  TNQDGRTALHLACRGGYTNIVQILIAAGTDVNRRTVDGKTCLHVAVWRGHTEVVVKLVNA 330

Query: 1135 GADIEAQSERTKDTPLSLACSGGRQEVVELLLARGANKEHRNVSDYTPLSLAASGGYVNI 1194
            GAD+        + P S+ CS                          PL  AA   Y  I
Sbjct: 331  GADV--------NIPDSVGCS--------------------------PLYWAARSNYTAI 408

Query: 1195 IKILLNAGAEINSRTGSKLGISPLMLAAMNGHTAAVKLLLDMGSDINAQIETNRNTALTL 1254
            + +L+NAGA++N R  SK   +PL  A   GH   V+ LL  G++ N  +          
Sbjct: 409  LTVLVNAGAKVNYRVKSKW--TPLHAALHLGHMGVVRYLLLQGAETNITV---------- 552

Query: 1255 ACFQGRTEVVSLLLDRKANVEHRAK 1279
               Q +T VVSLL+D + ++ H+ +
Sbjct: 553  ---QDKT-VVSLLMDNE-HLSHKER 612

 Score = 77.0 bits (188), Expect = 9e-14,   Method: Composition-based stats.
 Identities = 51/162 (31%), Positives = 79/162 (48%)
 Frame = +1

Query: 297 DITPLMAAANGGHVKIVKLLLAHKADVNAQSSTGNTALTYACAGGYVDVVKVLLESGASI 356
           D T L  A +     +V++L+   A+ N+ +  G TAL  AC GGY ++V++L+ +G  +
Sbjct: 64  DSTLLHEAVSMASEDLVQMLIKAGANANSTNQDGRTALHLACRGGYTNIVQILIAAGTDV 243

Query: 357 EDHNENGHTPLMEAGSAGHVEVARLLLENGAGINTHSNEFKESALTLACYKGHLEMVRFL 416
                +G T L  A   GH EV   L+  GA +N   +    S L  A    +  ++  L
Sbjct: 244 NRRTVDGKTCLHVAVWRGHTEVVVKLVNAGADVNI-PDSVGCSPLYWAARSNYTAILTVL 420

Query: 417 LEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNM 458
           + AGA   ++     T L  A   GH+ V R LL  GA+ N+
Sbjct: 421 VNAGAKVNYRVKSKWTPLHAALHLGHMGVVRYLLLQGAETNI 546

 Score = 66.6 bits (161), Expect = 1e-10,   Method: Composition-based stats.
 Identities = 46/139 (33%), Positives = 71/139 (51%)
 Frame = +1

Query: 576 VKYLLAAGANVHATTATGDTALTYACENGHTDVADVLLQAGADLEHESEGGRTPLMKAAR 635
           V+ L+  G +V+A      T L  A      D+  +L++AGA+    ++ GRT L  A R
Sbjct: 13  VQRLVKGGVDVNARFWYDSTLLHEAVSMASEDLVQMLIKAGANANSTNQDGRTALHLACR 192

Query: 636 AGHVCTVQFLISKGANVNRTTANNDHTVLSLACAGGHLAVVELLLAHGADPTHRLKDGST 695
            G+   VQ LI+ G +VNR T +   T L +A   GH  VV  L+  GAD       G +
Sbjct: 193 GGYTNIVQILIAAGTDVNRRTVDGK-TCLHVAVWRGHTEVVVKLVNAGADVNIPDSVGCS 369

Query: 696 MLIEAAKGGHTSVVCYLLD 714
            L  AA+  +T+++  L++
Sbjct: 370 PLYWAARSNYTAILTVLVN 426
>11295
          Length = 1179

 Score = 85.5 bits (210), Expect = 3e-16,   Method: Composition-based stats.
 Identities = 86/305 (28%), Positives = 137/305 (44%), Gaps = 3/305 (0%)
 Frame = +1

Query: 1093 ELVQTLLERGASIEHRDKKGFTPLILAATAGHVGVVEILLD--NGADIEAQSERTKD-TP 1149
            + V TLL+ GA I   D +G + L  A    +  V E+LLD  NG  I   +      T 
Sbjct: 7    QTVLTLLQGGAQIYWTDHRGLSALHHACIGRNTEVAELLLDGWNGDGIAVNATSNDHVTA 186

Query: 1150 LSLACSGGRQEVVELLLARGANKEHRNVSDYTPLSLAASGGYVNIIKILLNAGAEINSRT 1209
            L +AC    +E+  LLL  GA     +V  +TPL +A   G   + ++LL+  ++++   
Sbjct: 187  LHIACCLDDREMASLLLKYGAYAMALDVIGHTPLHVACWCGSEGVTRLLLDR-SDVDVNA 363

Query: 1210 GSKLGISPLMLAAMNGHTAAVKLLLDMGSDINAQIETNRNTALTLACFQGRTEVVSLLLD 1269
                G  PL LA+  G    ++ LL   +D   + +    T    A    R   V   L 
Sbjct: 364  LDHDGKXPLRLASECGFHYIIRQLLYHNADHTIR-DAAEFTPFHCAIRYCRVLAVKTFLV 540

Query: 1270 RKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADVNAPPVPSSRDTALTIAADKGHY 1329
               ++ H     L+P   A      E+  +L+  GA VN         T L   + +GH 
Sbjct: 541  WFPDLIHSFYNDLSPTFMACLQCDKEMLSLLIKFGASVNC--ADHYHYTPLHYISRRGHL 714

Query: 1330 KFCELLIGKGAHIDVRNKKGNTPLWLAANGGHLDVVQLLVQATADVDAADNRKITPLMAA 1389
               +LL+   A  +V + +G TPL++A+  GH+ +V +L+Q+ A +     R   P+ AA
Sbjct: 715  TMLQLLLQGKAEPNVVDDEGITPLYIASCEGHVTIVNILLQSGAKIYMPCARD--PVHAA 888

Query: 1390 FRKGH 1394
             + GH
Sbjct: 889  CKAGH 903

 Score = 81.3 bits (199), Expect = 4e-15,   Method: Composition-based stats.
 Identities = 74/255 (29%), Positives = 113/255 (44%), Gaps = 1/255 (0%)
 Frame = +1

Query: 1075 TESNHDTALTLACAGGHEELVQTLLERGASIEHRDKKGFTPLILAATAGHVGVVEILLD- 1133
            T ++H TAL +AC     E+   LL+ GA     D  G TPL +A   G  GV  +LLD 
Sbjct: 163  TSNDHVTALHIACCLDDREMASLLLKYGAYAMALDVIGHTPLHVACWCGSEGVTRLLLDR 342

Query: 1134 NGADIEAQSERTKDTPLSLACSGGRQEVVELLLARGANKEHRNVSDYTPLSLAASGGYVN 1193
            +  D+ A     K  PL LA   G   ++  LL   A+   R+ +++TP   A     V 
Sbjct: 343  SDVDVNALDHDGK-XPLRLASECGFHYIIRQLLYHNADHTIRDAAEFTPFHCAIRYCRVL 519

Query: 1194 IIKILLNAGAEINSRTGSKLGISPLMLAAMNGHTAAVKLLLDMGSDINAQIETNRNTALT 1253
             +K  L    ++     + L  SP  +A +      + LL+  G+ +N   +    T L 
Sbjct: 520  AVKTFLVWFPDLIHSFYNDL--SPTFMACLQCDKEMLSLLIKFGASVNCA-DHYHYTPLH 690

Query: 1254 LACFQGRTEVVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADVNAPPVP 1313
                +G   ++ LLL  KA        G+TPL  A+  G+  +  +LL  GA +    +P
Sbjct: 691  YISRRGHLTMLQLLLQGKAEPNVVDDEGITPLYIASCEGHVTIVNILLQSGAKIY---MP 861

Query: 1314 SSRDTALTIAADKGH 1328
             +RD  +  A   GH
Sbjct: 862  CARD-PVHAACKAGH 903

 Score = 75.9 bits (185), Expect = 2e-13,   Method: Composition-based stats.
 Identities = 84/291 (28%), Positives = 121/291 (41%), Gaps = 10/291 (3%)
 Frame = +1

Query: 242 DVNAVRKLLIEGRSVNEHTEEGESLLCLACSAGYYELAQVLL--------AMHANVEDRG 293
           D   V  LL  G  +      G S L  AC     E+A++LL        A++A   D  
Sbjct: 1   DRQTVLTLLQGGAQIYWTDHRGLSALHHACIGRNTEVAELLLDGWNGDGIAVNATSNDH- 177

Query: 294 IKGDITPLMAAANGGHVKIVKLLLAHKADVNAQSSTGNTALTYACAGGYVDVVKVLLE-S 352
               +T L  A      ++  LLL + A   A    G+T L  AC  G   V ++LL+ S
Sbjct: 178 ----VTALHIACCLDDREMASLLLKYGAYAMALDVIGHTPLHVACWCGSEGVTRLLLDRS 345

Query: 353 GASIEDHNENGHTPLMEAGSAG-HVEVARLLLENGAGINTHSNEFKESALTLACYKGHLE 411
              +   + +G  PL  A   G H  + +LL  N       + EF  +    A     + 
Sbjct: 346 DVDVNALDHDGKXPLRLASECGFHYIIRQLLYHNADHTIRDAAEF--TPFHCAIRYCRVL 519

Query: 412 MVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAA 471
            V+  L    D  H      +    AC+    E+  LL+  GA VN       +PL   +
Sbjct: 520 AVKTFLVWFPDLIHSFYNDLSPTFMACLQCDKEMLSLLIKFGASVNCADHYHYTPLHYIS 699

Query: 472 CGGHVELAALLIERGASLEEVNDEGYTPLMEAAREGHEEMVALLLGQGANI 522
             GH+ +  LL++  A    V+DEG TPL  A+ EGH  +V +LL  GA I
Sbjct: 700 RRGHLTMLQLLLQGKAEPNVVDDEGITPLYIASCEGHVTIVNILLQSGAKI 852

 Score = 73.9 bits (180), Expect = 8e-13,   Method: Composition-based stats.
 Identities = 83/303 (27%), Positives = 124/303 (40%), Gaps = 41/303 (13%)
 Frame = +1

Query: 411 EMVRFLLEAGADQEHKTDEMH-TALMEACMDGHVEVARLLLD----SGAQVNMPADSFES 465
           + V  LL+ GA Q + TD    +AL  AC+  + EVA LLLD     G  VN  ++   +
Sbjct: 7   QTVLTLLQGGA-QIYWTDHRGLSALHHACIGRNTEVAELLLDGWNGDGIAVNATSNDHVT 183

Query: 466 PLTLAACGGHVELAALLIERGASLEEVNDEGYTPLMEAAREGHEEMVALLLGQG-ANINX 524
            L +A C    E+A+LL++ GA    ++  G+TPL  A   G E +  LLL +   ++N 
Sbjct: 184 ALHIACCLDDREMASLLLKYGAYAMALDVIGHTPLHVACWCGSEGVTRLLLDRSDVDVNA 363

Query: 525 XXXXXXXXXXXXXCCGGFLEV-------ADFLIKAGADIE-LGCS--------------- 561
                         CG    +       AD  I+  A+     C+               
Sbjct: 364 LDHDGKXPLRLASECGFHYIIRQLLYHNADHTIRDAAEFTPFHCAIRYCRVLAVKTFLVW 543

Query: 562 ------------TPLMEAAQEGHLELVKYLLAAGANVHATTATGDTALTYACENGHTDVA 609
                       +P   A  +   E++  L+  GA+V+       T L Y    GH  + 
Sbjct: 544 FPDLIHSFYNDLSPTFMACLQCDKEMLSLLIKFGASVNCADHYHYTPLHYISRRGHLTML 723

Query: 610 DVLLQAGADLEHESEGGRTPLMKAARAGHVCTVQFLISKGANVNRTTANNDHTVLSLACA 669
            +LLQ  A+     + G TPL  A+  GHV  V  L+  GA +    A +    +  AC 
Sbjct: 724 QLLLQGKAEPNVVDDEGITPLYIASCEGHVTIVNILLQSGAKIYMPCARDP---VHAACK 894

Query: 670 GGH 672
            GH
Sbjct: 895 AGH 903

 Score = 50.8 bits (120), Expect = 7e-06,   Method: Composition-based stats.
 Identities = 33/86 (38%), Positives = 43/86 (50%)
 Frame = +1

Query: 1079 HDTALTLACAGGHEELVQTLLERGASIEHRDKKGFTPLILAATAGHVGVVEILLDNGADI 1138
            H T L      GH  ++Q LL+  A     D +G TPL +A+  GHV +V ILL +GA I
Sbjct: 673  HYTPLHYISRRGHLTMLQLLLQGKAEPNVVDDEGITPLYIASCEGHVTIVNILLQSGAKI 852

Query: 1139 EAQSERTKDTPLSLACSGGRQEVVEL 1164
                 R    P+  AC  G  EV+ L
Sbjct: 853  YMPCAR---DPVHAACKAG-HEVIAL 918
>00540
          Length = 3034

 Score = 83.6 bits (205), Expect = 9e-16,   Method: Compositional matrix adjust.
 Identities = 43/119 (36%), Positives = 73/119 (61%)
 Frame = -2

Query: 299  TPLMAAANGGHVKIVKLLLAHKADVNAQSSTGNTALTYACAGGYVDVVKVLLESGASIED 358
            TPL AA   GH+++V+ L+ HKA++   +S G+T L  AC  G++DVV+ LL  GA +  
Sbjct: 2964 TPLRAACYDGHLEVVQFLVEHKAEIEIANSHGHTCLMIACYRGHLDVVEYLLYLGAQVNR 2785

Query: 359  HNENGHTPLMEAGSAGHVEVARLLLENGAGINTHSNEFKESALTLACYKGHLEMVRFLL 417
             +  G+T L ++  +G + + +LLL  GA +    + + ++ L+ A   GH E+VR+L+
Sbjct: 2784 RSVKGNTALHDSAESGKLSIMKLLLSKGAKMA--KDAYGQTPLSAAAMTGHEEIVRYLI 2614

 Score = 81.6 bits (200), Expect = 3e-15,   Method: Compositional matrix adjust.
 Identities = 55/134 (41%), Positives = 75/134 (55%), Gaps = 2/134 (1%)
 Frame = -2

Query: 385  NGAGIN--THSNEFKESALTLACYKGHLEMVRFLLEAGADQEHKTDEMHTALMEACMDGH 442
             GA +N  T SN    + L  ACY GHLE+V+FL+E  A+ E      HT LM AC  GH
Sbjct: 3003 KGAEVNQTTRSNS---TPLRAACYDGHLEVVQFLVEHKAEIEIANSHGHTCLMIACYRGH 2833

Query: 443  VEVARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALLIERGASLEEVNDEGYTPLME 502
            ++V   LL  GAQVN  +    + L  +A  G + +  LL+ +GA + + +  G TPL  
Sbjct: 2832 LDVVEYLLYLGAQVNRRSVKGNTALHDSAESGKLSIMKLLLSKGAKMAK-DAYGQTPLSA 2656

Query: 503  AAREGHEEMVALLL 516
            AA  GHEE+V  L+
Sbjct: 2655 AAMTGHEEIVRYLI 2614

 Score = 74.3 bits (181), Expect = 6e-13,   Method: Compositional matrix adjust.
 Identities = 52/138 (37%), Positives = 75/138 (54%), Gaps = 2/138 (1%)
 Frame = -2

Query: 581  AAGANVHATTATGDTALTYACENGHTDVADVLLQAGADLEHESEGGRTPLMKAARAGHVC 640
            A GA V+ TT +  T L  AC +GH +V   L++  A++E  +  G T LM A   GH+ 
Sbjct: 3006 AKGAEVNQTTRSNSTPLRAACYDGHLEVVQFLVEHKAEIEIANSHGHTCLMIACYRGHLD 2827

Query: 641  TVQFLISKGANVNRTTANNDHTVLSLACAGGHLAVVELLLAHGADPTHRLKD--GSTMLI 698
             V++L+  GA VNR +   + T L  +   G L++++LLL+ GA      KD  G T L 
Sbjct: 2826 VVEYLLYLGAQVNRRSVKGN-TALHDSAESGKLSIMKLLLSKGAKMA---KDAYGQTPLS 2659

Query: 699  EAAKGGHTSVVCYLLDYP 716
             AA  GH  +V YL+  P
Sbjct: 2658 AAAMTGHEEIVRYLISGP 2605

 Score = 74.3 bits (181), Expect = 7e-13,   Method: Compositional matrix adjust.
 Identities = 44/121 (36%), Positives = 64/121 (52%)
 Frame = -2

Query: 561  STPLMEAAQEGHLELVKYLLAAGANVHATTATGDTALTYACENGHTDVADVLLQAGADLE 620
            STPL  A  +GHLE+V++L+   A +    + G T L  AC  GH DV + LL  GA + 
Sbjct: 2967 STPLRAACYDGHLEVVQFLVEHKAEIEIANSHGHTCLMIACYRGHLDVVEYLLYLGAQVN 2788

Query: 621  HESEGGRTPLMKAARAGHVCTVQFLISKGANVNRTTANNDHTVLSLACAGGHLAVVELLL 680
              S  G T L  +A +G +  ++ L+SKGA + +       T LS A   GH  +V  L+
Sbjct: 2787 RRSVKGNTALHDSAESGKLSIMKLLLSKGAKMAKDAYGQ--TPLSAAAMTGHEEIVRYLI 2614

Query: 681  A 681
            +
Sbjct: 2613 S 2611

 Score = 73.6 bits (179), Expect = 1e-12,   Method: Compositional matrix adjust.
 Identities = 48/127 (37%), Positives = 74/127 (58%)
 Frame = -2

Query: 1074 QTESNHDTALTLACAGGHEELVQTLLERGASIEHRDKKGFTPLILAATAGHVGVVEILLD 1133
            QT  ++ T L  AC  GH E+VQ L+E  A IE  +  G T L++A   GH+ VVE LL 
Sbjct: 2985 QTTRSNSTPLRAACYDGHLEVVQFLVEHKAEIEIANSHGHTCLMIACYRGHLDVVEYLLY 2806

Query: 1134 NGADIEAQSERTKDTPLSLACSGGRQEVVELLLARGANKEHRNVSDYTPLSLAASGGYVN 1193
             GA +  +S +  +T L  +   G+  +++LLL++GA K  ++    TPLS AA  G+  
Sbjct: 2805 LGAQVNRRSVK-GNTALHDSAESGKLSIMKLLLSKGA-KMAKDAYGQTPLSAAAMTGHEE 2632

Query: 1194 IIKILLN 1200
            I++ L++
Sbjct: 2631 IVRYLIS 2611

 Score = 72.8 bits (177), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 48/134 (35%), Positives = 72/134 (53%)
 Frame = -2

Query: 1101 RGASIEHRDKKGFTPLILAATAGHVGVVEILLDNGADIEAQSERTKDTPLSLACSGGRQE 1160
            +GA +    +   TPL  A   GH+ VV+ L+++ A+IE  +     T L +AC  G  +
Sbjct: 3003 KGAEVNQTTRSNSTPLRAACYDGHLEVVQFLVEHKAEIEIANSHGH-TCLMIACYRGHLD 2827

Query: 1161 VVELLLARGANKEHRNVSDYTPLSLAASGGYVNIIKILLNAGAEINSRTGSKLGISPLML 1220
            VVE LL  GA    R+V   T L  +A  G ++I+K+LL+ GA++        G +PL  
Sbjct: 2826 VVEYLLYLGAQVNRRSVKGNTALHDSAESGKLSIMKLLLSKGAKMAK---DAYGQTPLSA 2656

Query: 1221 AAMNGHTAAVKLLL 1234
            AAM GH   V+ L+
Sbjct: 2655 AAMTGHEEIVRYLI 2614

 Score = 70.9 bits (172), Expect = 6e-12,   Method: Compositional matrix adjust.
 Identities = 49/133 (36%), Positives = 72/133 (54%)
 Frame = -2

Query: 1237 GSDINAQIETNRNTALTLACFQGRTEVVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEV 1296
            G+++N    +N +T L  AC+ G  EVV  L++ KA +E     G T LM A   G+ +V
Sbjct: 3000 GAEVNQTTRSN-STPLRAACYDGHLEVVQFLVEHKAEIEIANSHGHTCLMIACYRGHLDV 2824

Query: 1297 GRVLLDKGADVNAPPVPSSRDTALTIAADKGHYKFCELLIGKGAHIDVRNKKGNTPLWLA 1356
               LL  GA VN   V    +TAL  +A+ G     +LL+ KGA +  ++  G TPL  A
Sbjct: 2823 VEYLLYLGAQVNRRSVKG--NTALHDSAESGKLSIMKLLLSKGAKM-AKDAYGQTPLSAA 2653

Query: 1357 ANGGHLDVVQLLV 1369
            A  GH ++V+ L+
Sbjct: 2652 AMTGHEEIVRYLI 2614

 Score = 70.9 bits (172), Expect = 7e-12,   Method: Compositional matrix adjust.
 Identities = 50/133 (37%), Positives = 71/133 (53%)
 Frame = -2

Query: 318  AHKADVNAQSSTGNTALTYACAGGYVDVVKVLLESGASIEDHNENGHTPLMEAGSAGHVE 377
            A  A+VN  + + +T L  AC  G+++VV+ L+E  A IE  N +GHT LM A   GH++
Sbjct: 3006 AKGAEVNQTTRSNSTPLRAACYDGHLEVVQFLVEHKAEIEIANSHGHTCLMIACYRGHLD 2827

Query: 378  VARLLLENGAGINTHSNEFKESALTLACYKGHLEMVRFLLEAGADQEHKTDEMHTALMEA 437
            V   LL  GA +N  S +   +AL  +   G L +++ LL  GA    K     T L  A
Sbjct: 2826 VVEYLLYLGAQVNRRSVK-GNTALHDSAESGKLSIMKLLLSKGAKMA-KDAYGQTPLSAA 2653

Query: 438  CMDGHVEVARLLL 450
             M GH E+ R L+
Sbjct: 2652 AMTGHEEIVRYLI 2614

 Score = 69.3 bits (168), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 53/166 (31%), Positives = 77/166 (46%), Gaps = 3/166 (1%)
 Frame = -2

Query: 485  RGASLEEVNDEGYTPLMEAAREGHEEMVALLLGQGANINXXXXXXXXXXXXXXCCGGFLE 544
            +GA + +      TPL  A  +GH                                  LE
Sbjct: 3003 KGAEVNQTTRSNSTPLRAACYDGH----------------------------------LE 2926

Query: 545  VADFLIKAGADIELGCS---TPLMEAAQEGHLELVKYLLAAGANVHATTATGDTALTYAC 601
            V  FL++  A+IE+  S   T LM A   GHL++V+YLL  GA V+  +  G+TAL  + 
Sbjct: 2925 VVQFLVEHKAEIEIANSHGHTCLMIACYRGHLDVVEYLLYLGAQVNRRSVKGNTALHDSA 2746

Query: 602  ENGHTDVADVLLQAGADLEHESEGGRTPLMKAARAGHVCTVQFLIS 647
            E+G   +  +LL  GA +  ++  G+TPL  AA  GH   V++LIS
Sbjct: 2745 ESGKLSIMKLLLSKGAKMAKDAY-GQTPLSAAAMTGHEEIVRYLIS 2611

 Score = 66.2 bits (160), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 45/131 (34%), Positives = 63/131 (48%), Gaps = 2/131 (1%)
 Frame = -2

Query: 453  GAQVNMPADSFESPLTLAACGGHVELAALLIERGASLEEVNDEGYTPLMEAAREGHEEMV 512
            GA+VN    S  +PL  A   GH+E+   L+E  A +E  N  G+T LM A   GH ++V
Sbjct: 3000 GAEVNQTTRSNSTPLRAACYDGHLEVVQFLVEHKAEIEIANSHGHTCLMIACYRGHLDVV 2821

Query: 513  ALLLGQGANINXXXXXXXXXXXXXXCCGGFLEVADFLIKAGADI--ELGCSTPLMEAAQE 570
              LL  GA +N                G  L +   L+  GA +  +    TPL  AA  
Sbjct: 2820 EYLLYLGAQVNRRSVKGNTALHDSAESGK-LSIMKLLLSKGAKMAKDAYGQTPLSAAAMT 2644

Query: 571  GHLELVKYLLA 581
            GH E+V+YL++
Sbjct: 2643 GHEEIVRYLIS 2611

 Score = 60.8 bits (146), Expect = 6e-09,   Method: Compositional matrix adjust.
 Identities = 44/135 (32%), Positives = 69/135 (51%)
 Frame = -2

Query: 1167 ARGANKEHRNVSDYTPLSLAASGGYVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGH 1226
            A+GA       S+ TPL  A   G++ +++ L+   AEI     +  G + LM+A   GH
Sbjct: 3006 AKGAEVNQTTRSNSTPLRAACYDGHLEVVQFLVEHKAEIE--IANSHGHTCLMIACYRGH 2833

Query: 1227 TAAVKLLLDMGSDINAQIETNRNTALTLACFQGRTEVVSLLLDRKANVEHRAKTGLTPLM 1286
               V+ LL +G+ +N +     NTAL  +   G+  ++ LLL + A +   A  G TPL 
Sbjct: 2832 LDVVEYLLYLGAQVNRR-SVKGNTALHDSAESGKLSIMKLLLSKGAKMAKDA-YGQTPLS 2659

Query: 1287 EAASGGYAEVGRVLL 1301
             AA  G+ E+ R L+
Sbjct: 2658 AAAMTGHEEIVRYLI 2614

 Score = 56.6 bits (135), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 37/123 (30%), Positives = 67/123 (54%)
 Frame = -2

Query: 228  QSDNRSLAEACSEGDVNAVRKLLIEGRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHA 287
            +S++  L  AC +G +  V+ L+     +      G + L +AC  G+ ++ + LL + A
Sbjct: 2976 RSNSTPLRAACYDGHLEVVQFLVEHKAEIEIANSHGHTCLMIACYRGHLDVVEYLLYLGA 2797

Query: 288  NVEDRGIKGDITPLMAAANGGHVKIVKLLLAHKADVNAQSSTGNTALTYACAGGYVDVVK 347
             V  R +KG+ T L  +A  G + I+KLLL+  A + A+ + G T L+ A   G+ ++V+
Sbjct: 2796 QVNRRSVKGN-TALHDSAESGKLSIMKLLLSKGAKM-AKDAYGQTPLSAAAMTGHEEIVR 2623

Query: 348  VLL 350
             L+
Sbjct: 2622 YLI 2614

 Score = 55.1 bits (131), Expect = 4e-07,   Method: Compositional matrix adjust.
 Identities = 27/65 (41%), Positives = 41/65 (63%)
 Frame = -2

Query: 1338 KGAHIDVRNKKGNTPLWLAANGGHLDVVQLLVQATADVDAADNRKITPLMAAFRKGHVKV 1397
            KGA ++   +  +TPL  A   GHL+VVQ LV+  A+++ A++   T LM A  +GH+ V
Sbjct: 3003 KGAEVNQTTRSNSTPLRAACYDGHLEVVQFLVEHKAEIEIANSHGHTCLMIACYRGHLDV 2824

Query: 1398 VRYLV 1402
            V YL+
Sbjct: 2823 VEYLL 2809

 Score = 54.3 bits (129), Expect = 6e-07,   Method: Compositional matrix adjust.
 Identities = 42/132 (31%), Positives = 59/132 (44%), Gaps = 32/132 (24%)
 Frame = -2

Query: 1303 KGADVNAPPVPSSRDTALTIAADKGHYKFCELLIGKGAHIDVRNKKGNTPLWLAANGGHL 1362
            KGA+VN      S  T L  A   GH +  + L+   A I++ N  G+T L +A   GHL
Sbjct: 3003 KGAEVN--QTTRSNSTPLRAACYDGHLEVVQFLVEHKAEIEIANSHGHTCLMIACYRGHL 2830

Query: 1363 DVVQLLVQATADV------------DAADNRKI--------------------TPLMAAF 1390
            DVV+ L+   A V            D+A++ K+                    TPL AA 
Sbjct: 2829 DVVEYLLYLGAQVNRRSVKGNTALHDSAESGKLSIMKLLLSKGAKMAKDAYGQTPLSAAA 2650

Query: 1391 RKGHVKVVRYLV 1402
              GH ++VRYL+
Sbjct: 2649 MTGHEEIVRYLI 2614
>02114
          Length = 1072

 Score = 80.1 bits (196), Expect = 1e-14,   Method: Compositional matrix adjust.
 Identities = 72/268 (26%), Positives = 125/268 (46%), Gaps = 10/268 (3%)
 Frame = +1

Query: 1111 KGFTPLILAATAGHVGVVEILLDNGADIEAQSERTKDTPLSLACSGGRQEVVELLLARGA 1170
            +G+TP  +AA  G  G ++ L +NG  + A+  R   TPL LAC+ G    V+ LL  G 
Sbjct: 199  RGWTPAHIAAIRGQEGCIQALSNNGVSMSAKDTRGS-TPLHLACAHGHSFCVQTLLRCGV 375

Query: 1171 NKEHRNVSDYTPLSLAASGGYVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHTAAV 1230
            +    + + +T + +++  G +  +++L+  GA  +    +  G +P  LAAM GH   +
Sbjct: 376  DVNSVDKTSWTSVHVSSYHGRLGCLQMLIKWGARYDDIDTN--GNTPAHLAAMEGHLPCL 549

Query: 1231 KLLLD--------MGSDINAQIETNRNTALTLACFQGRTEVVSLLLDRKANVEH--RAKT 1280
            K L+         +G+  N   ET R+ A        +  ++  +   +  ++H  +A+ 
Sbjct: 550  KFLVSSEGCPEHTLGAR-NDHGETPRDLAQQFY----KENILEYIDHVQHEMDHPEQAEN 714

Query: 1281 GLTPLMEAASGGYAEVGRVLLDKGADVNAPPVPSSRDTALTIAADKGHYKFCELLIGKGA 1340
               P   AA  G  +  R+L++ G  VN        +T    AA +GH    + L+  GA
Sbjct: 715  LAFPAHMAAYNGELDHLRILVENGV-VNINERDDKGNTLAHRAAGQGHLNILQWLVEMGA 891

Query: 1341 HIDVRNKKGNTPLWLAANGGHLDVVQLL 1368
             +++ N  G T   +A    HL  V+LL
Sbjct: 892  DVEISNGAGETARDIARRFAHLACVKLL 975

 Score = 64.7 bits (156), Expect = 5e-10,   Method: Compositional matrix adjust.
 Identities = 57/200 (28%), Positives = 97/200 (48%), Gaps = 5/200 (2%)
 Frame = +1

Query: 1081 TALTLACAGGHEELVQTLLERGASIEHRDKKGFTPLILAATAGHVGVVEILLDNGADIEA 1140
            T L LACA GH   VQTLL  G  +   DK  +T + +++  G +G +++L+  GA  + 
Sbjct: 307  TPLHLACAHGHSFCVQTLLRCGVDVNSVDKTSWTSVHVSSYHGRLGCLQMLIKWGARYD- 483

Query: 1141 QSERTKDTPLSLACSGGRQEVVELLLARGANKEH----RNVSDYTPLSLAASGGYVNIIK 1196
              +   +TP  LA   G    ++ L++     EH    RN    TP  LA      NI++
Sbjct: 484  DIDTNGNTPAHLAAMEGHLPCLKFLVSSEGCPEHTLGARNDHGETPRDLAQQFYKENILE 663

Query: 1197 ILLNAGAEINSRTGSKLGISPLMLAAMNGHTAAVKLLLDMG-SDINAQIETNRNTALTLA 1255
             + +   E++    ++    P  +AA NG    +++L++ G  +IN + +   NT    A
Sbjct: 664  YIDHVQHEMDHPEQAENLAFPAHMAAYNGELDHLRILVENGVVNINER-DDKGNTLAHRA 840

Query: 1256 CFQGRTEVVSLLLDRKANVE 1275
              QG   ++  L++  A+VE
Sbjct: 841  AGQGHLNILQWLVEMGADVE 900

 Score = 59.3 bits (142), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 61/227 (26%), Positives = 103/227 (45%), Gaps = 7/227 (3%)
 Frame = +1

Query: 299 TPLMAAANGGHVKIVKLLLAHKADVNAQSSTGNTALTYACAGGYVDVVKVLLESGASIED 358
           TPL  A   GH   V+ LL    DVN+   T  T++  +   G +  +++L++ GA  +D
Sbjct: 307 TPLHLACAHGHSFCVQTLLRCGVDVNSVDKTSWTSVHVSSYHGRLGCLQMLIKWGARYDD 486

Query: 359 HNENGHTPLMEAGSAGHVEVARLLLENGAGINTHS----NEFKESALTLACYKGHLEMVR 414
            + NG+TP   A   GH+   + L+ +  G   H+    N+  E+   LA       ++ 
Sbjct: 487 IDTNGNTPAHLAAMEGHLPCLKFLVSS-EGCPEHTLGARNDHGETPRDLAQQFYKENILE 663

Query: 415 FLLEAGADQEHKTDEMHTAL--MEACMDGHVEVARLLLDSG-AQVNMPADSFESPLTLAA 471
           ++     + +H     + A     A  +G ++  R+L+++G   +N   D   +    AA
Sbjct: 664 YIDHVQHEMDHPEQAENLAFPAHMAAYNGELDHLRILVENGVVNINERDDKGNTLAHRAA 843

Query: 472 CGGHVELAALLIERGASLEEVNDEGYTPLMEAAREGHEEMVALLLGQ 518
             GH+ +   L+E GA +E  N  G T    A R  H   V LL G+
Sbjct: 844 GQGHLNILQWLVEMGADVEISNGAGETARDIARRFAHLACVKLLGGE 984

 Score = 52.8 bits (125), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 70/265 (26%), Positives = 100/265 (37%), Gaps = 43/265 (16%)
 Frame = +1

Query: 465 SPLTLAACGGHVELAALLIERGASLEEVNDEGYTPLMEAAREGHEEMVALLLGQGANINX 524
           +P  +AA  G       L   G S+   +  G TPL  A   GH   V  LL  G ++N 
Sbjct: 208 TPAHIAAIRGQEGCIQALSNNGVSMSAKDTRGSTPLHLACAHGHSFCVQTLLRCGVDVNS 387

Query: 525 XXXXXXXXXXXXXCCGGFLEVADFLIKAGA---DIELGCSTPLMEAAQEGHLELVKYLLA 581
                           G L     LIK GA   DI+   +TP   AA EGHL  +K+L++
Sbjct: 388 VDKTSWTSVHVSS-YHGRLGCLQMLIKWGARYDDIDTNGNTPAHLAAMEGHLPCLKFLVS 564

Query: 582 A-GANVHATTATGDTALT--------------------------------------YACE 602
           + G   H   A  D   T                                       A  
Sbjct: 565 SEGCPEHTLGARNDHGETPRDLAQQFYKENILEYIDHVQHEMDHPEQAENLAFPAHMAAY 744

Query: 603 NGHTDVADVLLQAG-ADLEHESEGGRTPLMKAARAGHVCTVQFLISKGANVNRTTANNDH 661
           NG  D   +L++ G  ++    + G T   +AA  GH+  +Q+L+  GA+V  +    + 
Sbjct: 745 NGELDHLRILVENGVVNINERDDKGNTLAHRAAGQGHLNILQWLVEMGADVEISNGAGE- 921

Query: 662 TVLSLACAGGHLAVVELLLAHGADP 686
           T   +A    HLA V+LL   G +P
Sbjct: 922 TARDIARRFAHLACVKLL---GGEP 987

 Score = 42.0 bits (97), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 24/82 (29%), Positives = 41/82 (50%)
 Frame = +1

Query: 1322 IAADKGHYKFCELLIGKGAHIDVRNKKGNTPLWLAANGGHLDVVQLLVQATADVDAADNR 1381
            IAA +G     + L   G  +  ++ +G+TPL LA   GH   VQ L++   DV++ D  
Sbjct: 220  IAAIRGQEGCIQALSNNGVSMSAKDTRGSTPLHLACAHGHSFCVQTLLRCGVDVNSVDKT 399

Query: 1382 KITPLMAAFRKGHVKVVRYLVK 1403
              T +  +   G +  ++ L+K
Sbjct: 400  SWTSVHVSSYHGRLGCLQMLIK 465

 Score = 34.7 bits (78), Expect = 0.52,   Method: Compositional matrix adjust.
 Identities = 16/44 (36%), Positives = 25/44 (56%)
 Frame = +3

Query: 1128 VEILLDNGADIEAQSERTKDTPLSLACSGGRQEVVELLLARGAN 1171
            +E+++ NGA I    +R   TP+  AC+ G  E +  LL  GA+
Sbjct: 48   LEVMVKNGASINEVEDRDNFTPVHTACNIGALECLHWLLWHGAD 179
>08473
          Length = 942

 Score = 74.7 bits (182), Expect = 5e-13,   Method: Compositional matrix adjust.
 Identities = 48/132 (36%), Positives = 73/132 (55%)
 Frame = -1

Query: 1070 DIDAQTESNHDTALTLACAGGHEELVQTLLERGASIEHRDKKGFTPLILAATAGHVGVVE 1129
            D+D + +SN  TAL  ACAG H   V  LL+ GA+    +  G TPL  AA  G + + +
Sbjct: 942  DVDMR-DSNDMTALHHACAGLHYGCVHALLQGGANPTCMEMGGKTPLFYAAHRGEISICK 766

Query: 1130 ILLDNGADIEAQSERTKDTPLSLACSGGRQEVVELLLARGANKEHRNVSDYTPLSLAASG 1189
            +L+D GA++ A +++   TPL +A   G +E VE LL RGAN    +   +  L  A + 
Sbjct: 765  LLVDKGANVNA-ADKMLITPLMVAAREGNREAVEFLLKRGANPNTADREGHLALYYAMAA 589

Query: 1190 GYVNIIKILLNA 1201
            G+  + ++  NA
Sbjct: 588  GHPELREVFANA 553

 Score = 67.4 bits (163), Expect = 8e-11,   Method: Compositional matrix adjust.
 Identities = 44/131 (33%), Positives = 69/131 (52%)
 Frame = -1

Query: 322 DVNAQSSTGNTALTYACAGGYVDVVKVLLESGASIEDHNENGHTPLMEAGSAGHVEVARL 381
           DV+ + S   TAL +ACAG +   V  LL+ GA+       G TPL  A   G + + +L
Sbjct: 942 DVDMRDSNDMTALHHACAGLHYGCVHALLQGGANPTCMEMGGKTPLFYAAHRGEISICKL 763

Query: 382 LLENGAGINTHSNEFKESALTLACYKGHLEMVRFLLEAGADQEHKTDEMHTALMEACMDG 441
           L++ GA +N  +++   + L +A  +G+ E V FLL+ GA+      E H AL  A   G
Sbjct: 762 LVDKGANVNA-ADKMLITPLMVAAREGNREAVEFLLKRGANPNTADREGHLALYYAMAAG 586

Query: 442 HVEVARLLLDS 452
           H E+  +  ++
Sbjct: 585 HPELREVFANA 553

 Score = 60.8 bits (146), Expect = 8e-09,   Method: Compositional matrix adjust.
 Identities = 35/86 (40%), Positives = 49/86 (56%)
 Frame = -1

Query: 1318 TALTIAADKGHYKFCELLIGKGAHIDVRNKKGNTPLWLAANGGHLDVVQLLVQATADVDA 1377
            TAL  A    HY     L+  GA+       G TPL+ AA+ G + + +LLV   A+V+A
Sbjct: 912  TALHHACAGLHYGCVHALLQGGANPTCMEMGGKTPLFYAAHRGEISICKLLVDKGANVNA 733

Query: 1378 ADNRKITPLMAAFRKGHVKVVRYLVK 1403
            AD   ITPLM A R+G+ + V +L+K
Sbjct: 732  ADKMLITPLMVAAREGNREAVEFLLK 655

 Score = 58.9 bits (141), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 37/94 (39%), Positives = 53/94 (56%)
 Frame = -1

Query: 1148 TPLSLACSGGRQEVVELLLARGANKEHRNVSDYTPLSLAASGGYVNIIKILLNAGAEINS 1207
            T L  AC+G     V  LL  GAN     +   TPL  AA  G ++I K+L++ GA +N+
Sbjct: 912  TALHHACAGLHYGCVHALLQGGANPTCMEMGGKTPLFYAAHRGEISICKLLVDKGANVNA 733

Query: 1208 RTGSKLGISPLMLAAMNGHTAAVKLLLDMGSDIN 1241
                K+ I+PLM+AA  G+  AV+ LL  G++ N
Sbjct: 732  --ADKMLITPLMVAAREGNREAVEFLLKRGANPN 637

 Score = 57.4 bits (137), Expect = 8e-08,   Method: Compositional matrix adjust.
 Identities = 36/92 (39%), Positives = 48/92 (52%)
 Frame = -1

Query: 432 TALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALLIERGASLEE 491
           TAL  AC   H      LL  GA         ++PL  AA  G + +  LL+++GA++  
Sbjct: 912 TALHHACAGLHYGCVHALLQGGANPTCMEMGGKTPLFYAAHRGEISICKLLVDKGANVNA 733

Query: 492 VNDEGYTPLMEAAREGHEEMVALLLGQGANIN 523
            +    TPLM AAREG+ E V  LL +GAN N
Sbjct: 732 ADKMLITPLMVAAREGNREAVEFLLKRGANPN 637

 Score = 57.0 bits (136), Expect = 9e-08,   Method: Compositional matrix adjust.
 Identities = 44/139 (31%), Positives = 72/139 (51%), Gaps = 4/139 (2%)
 Frame = -1

Query: 1245 ETNRNTALTLACFQGRTEVVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKG 1304
            ++N  TAL  AC       V  LL   AN       G TPL  AA  G   + ++L+DKG
Sbjct: 927  DSNDMTALHHACAGLHYGCVHALLQGGANPTCMEMGGKTPLFYAAHRGEISICKLLVDKG 748

Query: 1305 ADVNAPPVPSSRDTALTIAADKGHYKFCELLIGKGAHIDVRNKKGNTPLWLAANGGHLDV 1364
            A+VNA        T L +AA +G+ +  E L+ +GA+ +  +++G+  L+ A   GH ++
Sbjct: 747  ANVNA--ADKMLITPLMVAAREGNREAVEFLLKRGANPNTADREGHLALYYAMAAGHPEL 574

Query: 1365 VQLL----VQATADVDAAD 1379
             ++     +QA+ D+ + D
Sbjct: 573  REVFANAPLQASWDLRSPD 517

 Score = 56.6 bits (135), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 42/118 (35%), Positives = 54/118 (45%)
 Frame = -1

Query: 562 TPLMEAAQEGHLELVKYLLAAGANVHATTATGDTALTYACENGHTDVADVLLQAGADLEH 621
           T L  A    H   V  LL  GAN       G T L YA   G   +  +L+  GA++  
Sbjct: 912 TALHHACAGLHYGCVHALLQGGANPTCMEMGGKTPLFYAAHRGEISICKLLVDKGANVNA 733

Query: 622 ESEGGRTPLMKAARAGHVCTVQFLISKGANVNRTTANNDHTVLSLACAGGHLAVVELL 679
             +   TPLM AAR G+   V+FL+ +GAN N T     H  L  A A GH  + E+ 
Sbjct: 732 ADKMLITPLMVAAREGNREAVEFLLKRGANPN-TADREGHLALYYAMAAGHPELREVF 562

 Score = 54.7 bits (130), Expect = 5e-07,   Method: Compositional matrix adjust.
 Identities = 52/168 (30%), Positives = 73/168 (43%), Gaps = 4/168 (2%)
 Frame = -1

Query: 456 VNMPADSFESPLTLAACGGHVELAALLIERGASLEEVNDEGYTPLMEAAREGHEEMVALL 515
           V+M   +  + L  A  G H      L++ GA+   +   G TPL  AA  G   +  LL
Sbjct: 939 VDMRDSNDMTALHHACAGLHYGCVHALLQGGANPTCMEMGGKTPLFYAAHRGEISICKLL 760

Query: 516 LGQGANINXXXXXXXXXXXXXXCCGGFLEVADFLIKAGADIELGCSTPLMEAAQEGHLEL 575
           + +GAN+N                      AD ++           TPLM AA+EG+ E 
Sbjct: 759 VDKGANVN---------------------AADKMLI----------TPLMVAAREGNREA 673

Query: 576 VKYLLAAGANVHATTATGDTALTYACENGHTDVADVL----LQAGADL 619
           V++LL  GAN +     G  AL YA   GH ++ +V     LQA  DL
Sbjct: 672 VEFLLKRGANPNTADREGHLALYYAMAAGHPELREVFANAPLQASWDL 529

 Score = 52.8 bits (125), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 38/122 (31%), Positives = 59/122 (48%)
 Frame = -1

Query: 1273 NVEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADVNAPPVPSSRDTALTIAADKGHYKFC 1332
            +V+ R    +T L  A +G +      LL  GA  N   +     T L  AA +G    C
Sbjct: 942  DVDMRDSNDMTALHHACAGLHYGCVHALLQGGA--NPTCMEMGGKTPLFYAAHRGEISIC 769

Query: 1333 ELLIGKGAHIDVRNKKGNTPLWLAANGGHLDVVQLLVQATADVDAADNRKITPLMAAFRK 1392
            +LL+ KGA+++  +K   TPL +AA  G+ + V+ L++  A+ + AD      L  A   
Sbjct: 768  KLLVDKGANVNAADKMLITPLMVAAREGNREAVEFLLKRGANPNTADREGHLALYYAMAA 589

Query: 1393 GH 1394
            GH
Sbjct: 588  GH 583

 Score = 49.7 bits (117), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 39/113 (34%), Positives = 54/113 (47%)
 Frame = -1

Query: 270 ACSAGYYELAQVLLAMHANVEDRGIKGDITPLMAAANGGHVKIVKLLLAHKADVNAQSST 329
           AC+  +Y     LL   AN     + G  TPL  AA+ G + I KLL+   A+VNA    
Sbjct: 897 ACAGLHYGCVHALLQGGANPTCMEMGGK-TPLFYAAHRGEISICKLLVDKGANVNAADKM 721

Query: 330 GNTALTYACAGGYVDVVKVLLESGASIEDHNENGHTPLMEAGSAGHVEVARLL 382
             T L  A   G  + V+ LL+ GA+    +  GH  L  A +AGH E+  + 
Sbjct: 720 LITPLMVAAREGNREAVEFLLKRGANPNTADREGHLALYYAMAAGHPELREVF 562

 Score = 45.4 bits (106), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 32/82 (39%), Positives = 40/82 (48%)
 Frame = -1

Query: 658 NNDHTVLSLACAGGHLAVVELLLAHGADPTHRLKDGSTMLIEAAKGGHTSVVCYLLDYPN 717
           +ND T L  ACAG H   V  LL  GA+PT     G T L  AA  G  S+   L+D   
Sbjct: 924 SNDMTALHHACAGLHYGCVHALLQGGANPTCMEMGGKTPLFYAAHRGEISICKLLVDKGA 745

Query: 718 NLLAAPPPDVTQLTPPSHDLNR 739
           N+ AA    +T L   + + NR
Sbjct: 744 NVNAADKMLITPLMVAAREGNR 679

 Score = 43.1 bits (100), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 37/112 (33%), Positives = 51/112 (45%), Gaps = 2/112 (1%)
 Frame = -1

Query: 1226 HTAAVKLLLDMGSDINAQIETNRNTALTLACFQGRTEVVSLLLDRKANVEHRAKTGLTPL 1285
            H   V  LL  G++    +E    T L  A  +G   +  LL+D+ ANV    K  +TPL
Sbjct: 882  HYGCVHALLQGGANPTC-MEMGGKTPLFYAAHRGEISICKLLVDKGANVNAADKMLITPL 706

Query: 1286 MEAASGGYAEVGRVLLDKGADVNAPPVPSSRD--TALTIAADKGHYKFCELL 1335
            M AA  G  E    LL +GA+    P  + R+   AL  A   GH +  E+ 
Sbjct: 705  MVAAREGNREAVEFLLKRGAN----PNTADREGHLALYYAMAAGHPELREVF 562
>19166
          Length = 447

 Score = 71.2 bits (173), Expect = 5e-12,   Method: Compositional matrix adjust.
 Identities = 51/148 (34%), Positives = 81/148 (54%), Gaps = 1/148 (0%)
 Frame = +1

Query: 1231 KLLLDMGSDINAQIETNRNTALTLACFQGRTEVVSLLLDRKANVEHRAKTGLTPLMEAAS 1290
            KLLLD   + N++   N  T L +AC + R +VV LLL   A+++   ++GLTPL  ++ 
Sbjct: 10   KLLLDRKCEPNSR-ALNGFTPLHIACKKNRIKVVELLLKYGASIDATTESGLTPLHVSSF 186

Query: 1291 GGYAEVGRVLLDKGADVNAPPVPSSR-DTALTIAADKGHYKFCELLIGKGAHIDVRNKKG 1349
             G+  +   L+   A    P  P+ R +T+L +AA         +L+  GA +D R ++ 
Sbjct: 187  MGHMNIVIYLIQHNA---YPDTPTVRGETSLHLAARANQTDIIRILLRNGAAVDARAREQ 357

Query: 1350 NTPLWLAANGGHLDVVQLLVQATADVDA 1377
             TPL +A+  G++D V LL+Q  A  DA
Sbjct: 358  QTPLHIASRLGNVDNVVLLLQHGASADA 441

 Score = 69.7 bits (169), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 50/144 (34%), Positives = 77/144 (53%)
 Frame = +1

Query: 311 KIVKLLLAHKADVNAQSSTGNTALTYACAGGYVDVVKVLLESGASIEDHNENGHTPLMEA 370
           K  KLLL  K + N+++  G T L  AC    + VV++LL+ GASI+   E+G TPL  +
Sbjct: 1   KTAKLLLDRKCEPNSRALNGFTPLHIACKKNRIKVVELLLKYGASIDATTESGLTPLHVS 180

Query: 371 GSAGHVEVARLLLENGAGINTHSNEFKESALTLACYKGHLEMVRFLLEAGADQEHKTDEM 430
              GH+ +   L+++ A  +T +    E++L LA      +++R LL  GA  + +  E 
Sbjct: 181 SFMGHMNIVIYLIQHNAYPDTPTVR-GETSLHLAARANQTDIIRILLRNGAAVDARAREQ 357

Query: 431 HTALMEACMDGHVEVARLLLDSGA 454
            T L  A   G+V+   LLL  GA
Sbjct: 358 QTPLHIASRLGNVDNVVLLLQHGA 429

 Score = 68.6 bits (166), Expect = 4e-11,   Method: Compositional matrix adjust.
 Identities = 51/147 (34%), Positives = 76/147 (51%)
 Frame = +1

Query: 1096 QTLLERGASIEHRDKKGFTPLILAATAGHVGVVEILLDNGADIEAQSERTKDTPLSLACS 1155
            + LL+R      R   GFTPL +A     + VVE+LL  GA I+A +E +  TPL ++  
Sbjct: 10   KLLLDRKCEPNSRALNGFTPLHIACKKNRIKVVELLLKYGASIDATTE-SGLTPLHVSSF 186

Query: 1156 GGRQEVVELLLARGANKEHRNVSDYTPLSLAASGGYVNIIKILLNAGAEINSRTGSKLGI 1215
             G   +V  L+   A  +   V   T L LAA     +II+ILL  GA +++R   +   
Sbjct: 187  MGHMNIVIYLIQHNAYPDTPTVRGETSLHLAARANQTDIIRILLRNGAAVDARAREQQ-- 360

Query: 1216 SPLMLAAMNGHTAAVKLLLDMGSDINA 1242
            +PL +A+  G+   V LLL  G+  +A
Sbjct: 361  TPLHIASRLGNVDNVVLLLQHGASADA 441

 Score = 66.2 bits (160), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 49/139 (35%), Positives = 68/139 (48%)
 Frame = +1

Query: 1266 LLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADVNAPPVPSSRDTALTIAAD 1325
            LLLDRK     RA  G TPL  A      +V  +LL  GA ++A     S  T L +++ 
Sbjct: 13   LLLDRKCEPNSRALNGFTPLHIACKKNRIKVVELLLKYGASIDA--TTESGLTPLHVSSF 186

Query: 1326 KGHYKFCELLIGKGAHIDVRNKKGNTPLWLAANGGHLDVVQLLVQATADVDAADNRKITP 1385
             GH      LI   A+ D    +G T L LAA     D++++L++  A VDA    + TP
Sbjct: 187  MGHMNIVIYLIQHNAYPDTPTVRGETSLHLAARANQTDIIRILLRNGAAVDARAREQQTP 366

Query: 1386 LMAAFRKGHVKVVRYLVKE 1404
            L  A R G+V  V  L++ 
Sbjct: 367  LHIASRLGNVDNVVLLLQH 423

 Score = 64.3 bits (155), Expect = 7e-10,   Method: Compositional matrix adjust.
 Identities = 44/149 (29%), Positives = 78/149 (52%)
 Frame = +1

Query: 279 AQVLLAMHANVEDRGIKGDITPLMAAANGGHVKIVKLLLAHKADVNAQSSTGNTALTYAC 338
           A++LL        R + G  TPL  A     +K+V+LLL + A ++A + +G T L  + 
Sbjct: 7   AKLLLDRKCEPNSRALNG-FTPLHIACKKNRIKVVELLLKYGASIDATTESGLTPLHVSS 183

Query: 339 AGGYVDVVKVLLESGASIEDHNENGHTPLMEAGSAGHVEVARLLLENGAGINTHSNEFKE 398
             G++++V  L++  A  +     G T L  A  A   ++ R+LL NGA ++  + E ++
Sbjct: 184 FMGHMNIVIYLIQHNAYPDTPTVRGETSLHLAARANQTDIIRILLRNGAAVDARARE-QQ 360

Query: 399 SALTLACYKGHLEMVRFLLEAGADQEHKT 427
           + L +A   G+++ V  LL+ GA  +  T
Sbjct: 361 TPLHIASRLGNVDNVVLLLQHGASADATT 447

 Score = 62.8 bits (151), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 40/122 (32%), Positives = 64/122 (52%), Gaps = 3/122 (2%)
 Frame = +1

Query: 538 CCGGFLEVADFLIKAGADIELGCS---TPLMEAAQEGHLELVKYLLAAGANVHATTATGD 594
           C    ++V + L+K GA I+       TPL  ++  GH+ +V YL+   A     T  G+
Sbjct: 82  CKKNRIKVVELLLKYGASIDATTESGLTPLHVSSFMGHMNIVIYLIQHNAYPDTPTVRGE 261

Query: 595 TALTYACENGHTDVADVLLQAGADLEHESEGGRTPLMKAARAGHVCTVQFLISKGANVNR 654
           T+L  A     TD+  +LL+ GA ++  +   +TPL  A+R G+V  V  L+  GA+ + 
Sbjct: 262 TSLHLAARANQTDIIRILLRNGAAVDARAREQQTPLHIASRLGNVDNVVLLLQHGASADA 441

Query: 655 TT 656
           TT
Sbjct: 442 TT 447

 Score = 62.8 bits (151), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 41/129 (31%), Positives = 71/129 (55%)
 Frame = +1

Query: 1081 TALTLACAGGHEELVQTLLERGASIEHRDKKGFTPLILAATAGHVGVVEILLDNGADIEA 1140
            T L +AC     ++V+ LL+ GASI+   + G TPL +++  GH+ +V  L+ + A  + 
Sbjct: 64   TPLHIACKKNRIKVVELLLKYGASIDATTESGLTPLHVSSFMGHMNIVIYLIQHNAYPDT 243

Query: 1141 QSERTKDTPLSLACSGGRQEVVELLLARGANKEHRNVSDYTPLSLAASGGYVNIIKILLN 1200
             + R  +T L LA    + +++ +LL  GA  + R     TPL +A+  G V+ + +LL 
Sbjct: 244  PTVR-GETSLHLAARANQTDIIRILLRNGAAVDARAREQQTPLHIASRLGNVDNVVLLLQ 420

Query: 1201 AGAEINSRT 1209
             GA  ++ T
Sbjct: 421  HGASADATT 447

 Score = 62.0 bits (149), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 42/141 (29%), Positives = 74/141 (52%), Gaps = 1/141 (0%)
 Frame = +1

Query: 248 KLLIEGRSV-NEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGIKGDITPLMAAAN 306
           KLL++ +   N     G + L +AC     ++ ++LL   A++ D   +  +TPL  ++ 
Sbjct: 10  KLLLDRKCEPNSRALNGFTPLHIACKKNRIKVVELLLKYGASI-DATTESGLTPLHVSSF 186

Query: 307 GGHVKIVKLLLAHKADVNAQSSTGNTALTYACAGGYVDVVKVLLESGASIEDHNENGHTP 366
            GH+ IV  L+ H A  +  +  G T+L  A      D++++LL +GA+++       TP
Sbjct: 187 MGHMNIVIYLIQHNAYPDTPTVRGETSLHLAARANQTDIIRILLRNGAAVDARAREQQTP 366

Query: 367 LMEAGSAGHVEVARLLLENGA 387
           L  A   G+V+   LLL++GA
Sbjct: 367 LHIASRLGNVDNVVLLLQHGA 429

 Score = 59.7 bits (143), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 47/150 (31%), Positives = 78/150 (52%), Gaps = 3/150 (2%)
 Frame = +1

Query: 1163 ELLLARGANKEHRNVSDYTPLSLAASGGYVNIIKILLNAGAEINSRTGSKLGISPLMLAA 1222
            +LLL R      R ++ +TPL +A     + ++++LL  GA I++ T S  G++PL +++
Sbjct: 10   KLLLDRKCEPNSRALNGFTPLHIACKKNRIKVVELLLKYGASIDATTES--GLTPLHVSS 183

Query: 1223 MNGHTAAVKLLLDMGSDINAQIET---NRNTALTLACFQGRTEVVSLLLDRKANVEHRAK 1279
              GH   V  L+      NA  +T      T+L LA    +T+++ +LL   A V+ RA+
Sbjct: 184  FMGHMNIVIYLIQH----NAYPDTPTVRGETSLHLAARANQTDIIRILLRNGAAVDARAR 351

Query: 1280 TGLTPLMEAASGGYAEVGRVLLDKGADVNA 1309
               TPL  A+  G  +   +LL  GA  +A
Sbjct: 352  EQQTPLHIASRLGNVDNVVLLLQHGASADA 441

 Score = 59.3 bits (142), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 45/146 (30%), Positives = 75/146 (51%), Gaps = 1/146 (0%)
 Frame = +1

Query: 377 EVARLLLENGAGINTHS-NEFKESALTLACYKGHLEMVRFLLEAGADQEHKTDEMHTALM 435
           + A+LLL+     N+ + N F  + L +AC K  +++V  LL+ GA  +  T+   T L 
Sbjct: 1   KTAKLLLDRKCEPNSRALNGF--TPLHIACKKNRIKVVELLLKYGASIDATTESGLTPLH 174

Query: 436 EACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALLIERGASLEEVNDE 495
            +   GH+ +   L+   A  + P    E+ L LAA     ++  +L+  GA+++    E
Sbjct: 175 VSSFMGHMNIVIYLIQHNAYPDTPTVRGETSLHLAARANQTDIIRILLRNGAAVDARARE 354

Query: 496 GYTPLMEAAREGHEEMVALLLGQGAN 521
             TPL  A+R G+ + V LLL  GA+
Sbjct: 355 QQTPLHIASRLGNVDNVVLLLQHGAS 432

 Score = 57.4 bits (137), Expect = 8e-08,   Method: Compositional matrix adjust.
 Identities = 43/123 (34%), Positives = 65/123 (52%)
 Frame = +1

Query: 562 TPLMEAAQEGHLELVKYLLAAGANVHATTATGDTALTYACENGHTDVADVLLQAGADLEH 621
           TPL  A ++  +++V+ LL  GA++ ATT +G T L  +   GH ++   L+Q  A  + 
Sbjct: 64  TPLHIACKKNRIKVVELLLKYGASIDATTESGLTPLHVSSFMGHMNIVIYLIQHNAYPDT 243

Query: 622 ESEGGRTPLMKAARAGHVCTVQFLISKGANVNRTTANNDHTVLSLACAGGHLAVVELLLA 681
            +  G T L  AARA     ++ L+  GA V+   A    T L +A   G++  V LLL 
Sbjct: 244 PTVRGETSLHLAARANQTDIIRILLRNGAAVD-ARAREQQTPLHIASRLGNVDNVVLLLQ 420

Query: 682 HGA 684
           HGA
Sbjct: 421 HGA 429

 Score = 55.1 bits (131), Expect = 4e-07,   Method: Compositional matrix adjust.
 Identities = 43/128 (33%), Positives = 69/128 (53%)
 Frame = +1

Query: 1148 TPLSLACSGGRQEVVELLLARGANKEHRNVSDYTPLSLAASGGYVNIIKILLNAGAEINS 1207
            TPL +AC   R +VVELLL  GA+ +    S  TPL +++  G++NI+  L+   A  ++
Sbjct: 64   TPLHIACKKNRIKVVELLLKYGASIDATTESGLTPLHVSSFMGHMNIVIYLIQHNAYPDT 243

Query: 1208 RTGSKLGISPLMLAAMNGHTAAVKLLLDMGSDINAQIETNRNTALTLACFQGRTEVVSLL 1267
             T    G + L LAA    T  +++LL  G+ ++A+    + T L +A   G  + V LL
Sbjct: 244  PTVR--GETSLHLAARANQTDIIRILLRNGAAVDARAR-EQQTPLHIASRLGNVDNVVLL 414

Query: 1268 LDRKANVE 1275
            L   A+ +
Sbjct: 415  LQHGASAD 438

 Score = 52.8 bits (125), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 35/109 (32%), Positives = 55/109 (50%)
 Frame = +1

Query: 1295 EVGRVLLDKGADVNAPPVPSSRDTALTIAADKGHYKFCELLIGKGAHIDVRNKKGNTPLW 1354
            +  ++LLD+  + N+  +     T L IA  K   K  ELL+  GA ID   + G TPL 
Sbjct: 1    KTAKLLLDRKCEPNSRALNGF--TPLHIACKKNRIKVVELLLKYGASIDATTESGLTPLH 174

Query: 1355 LAANGGHLDVVQLLVQATADVDAADNRKITPLMAAFRKGHVKVVRYLVK 1403
            +++  GH+++V  L+Q  A  D    R  T L  A R     ++R L++
Sbjct: 175  VSSFMGHMNIVIYLIQHNAYPDTPTVRGETSLHLAARANQTDIIRILLR 321

 Score = 52.0 bits (123), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 38/123 (30%), Positives = 61/123 (49%)
 Frame = +1

Query: 593 GDTALTYACENGHTDVADVLLQAGADLEHESEGGRTPLMKAARAGHVCTVQFLISKGANV 652
           G T L  AC+     V ++LL+ GA ++  +E G TPL  ++  GH+  V +LI   A  
Sbjct: 58  GFTPLHIACKKNRIKVVELLLKYGASIDATTESGLTPLHVSSFMGHMNIVIYLIQHNAYP 237

Query: 653 NRTTANNDHTVLSLACAGGHLAVVELLLAHGADPTHRLKDGSTMLIEAAKGGHTSVVCYL 712
           +  T   + T L LA       ++ +LL +GA    R ++  T L  A++ G+   V  L
Sbjct: 238 DTPTVRGE-TSLHLAARANQTDIIRILLRNGAAVDARAREQQTPLHIASRLGNVDNVVLL 414

Query: 713 LDY 715
           L +
Sbjct: 415 LQH 423

 Score = 47.4 bits (111), Expect = 8e-05,   Method: Compositional matrix adjust.
 Identities = 30/110 (27%), Positives = 53/110 (48%)
 Frame = +1

Query: 414 RFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACG 473
           + LL+   +   +     T L  AC    ++V  LLL  GA ++   +S  +PL +++  
Sbjct: 10  KLLLDRKCEPNSRALNGFTPLHIACKKNRIKVVELLLKYGASIDATTESGLTPLHVSSFM 189

Query: 474 GHVELAALLIERGASLEEVNDEGYTPLMEAAREGHEEMVALLLGQGANIN 523
           GH+ +   LI+  A  +     G T L  AAR    +++ +LL  GA ++
Sbjct: 190 GHMNIVIYLIQHNAYPDTPTVRGETSLHLAARANQTDIIRILLRNGAAVD 339
>20036
          Length = 1849

 Score = 64.3 bits (155), Expect = 6e-10,   Method: Compositional matrix adjust.
 Identities = 47/134 (35%), Positives = 70/134 (52%), Gaps = 6/134 (4%)
 Frame = +3

Query: 323 VNAQSSTGNTALTYACAGGYVDVVKVLLESG-ASIEDHNENGHTPLMEAGSA-----GHV 376
           VN   S GN+A+ Y  +    D+V +LL++    ++  N+ G+TP M A  A      H 
Sbjct: 864 VNLVDSNGNSAIHYCVSHCNFDIVGLLLDTEVCDVKRPNKAGYTPTMLASLAFIQNDDHR 1043

Query: 377 EVARLLLENGAGINTHSNEFKESALTLACYKGHLEMVRFLLEAGADQEHKTDEMHTALME 436
           ++ R L   G  IN  + +  ++AL LA  +   +MV  LLE GAD   +  +  TALM 
Sbjct: 1044DIIRQLFLAG-DINACAEQTGQTALMLATSQCRTDMVELLLETGADCNQQDFDGSTALMC 1220

Query: 437 ACMDGHVEVARLLL 450
           AC  GH  + +LLL
Sbjct: 1221ACEHGHTAIVQLLL 1262

 Score = 60.8 bits (146), Expect = 7e-09,   Method: Compositional matrix adjust.
 Identities = 51/170 (30%), Positives = 80/170 (47%), Gaps = 7/170 (4%)
 Frame = +3

Query: 1244 IETNRNTALTLACFQGRTEVVSLLLDRK-ANVEHRAKTGLTPLMEAA-----SGGYAEVG 1297
            +++N N+A+         ++V LLLD +  +V+   K G TP M A+     +  + ++ 
Sbjct: 873  VDSNGNSAIHYCVSHCNFDIVGLLLDTEVCDVKRPNKAGYTPTMLASLAFIQNDDHRDII 1052

Query: 1298 RVLLDKGADVNAPPVPSSRDTALTIAADKGHYKFCELLIGKGAHIDVRNKKGNTPLWLAA 1357
            R L   G D+NA    + + TAL +A  +      ELL+  GA  + ++  G+T L  A 
Sbjct: 1053 RQLFLAG-DINACAEQTGQ-TALMLATSQCRTDMVELLLETGADCNQQDFDGSTALMCAC 1226

Query: 1358 NGGHLDVVQLLV-QATADVDAADNRKITPLMAAFRKGHVKVVRYLVKEVN 1406
              GH  +VQLL+ Q   D    DN   T L  A    H  +   L K +N
Sbjct: 1227 EHGHTAIVQLLLAQPHCDATLTDNENSTALSIAMEASHKDIGVILYKHLN 1376

 Score = 57.8 bits (138), Expect = 6e-08,   Method: Compositional matrix adjust.
 Identities = 40/126 (31%), Positives = 58/126 (46%), Gaps = 5/126 (3%)
 Frame = +3

Query: 562  TPLMEAA-----QEGHLELVKYLLAAGANVHATTATGDTALTYACENGHTDVADVLLQAG 616
            TP M A+      + H ++++ L  AG        TG TAL  A     TD+ ++LL+ G
Sbjct: 993  TPTMLASLAFIQNDDHRDIIRQLFLAGDINACAEQTGQTALMLATSQCRTDMVELLLETG 1172

Query: 617  ADLEHESEGGRTPLMKAARAGHVCTVQFLISKGANVNRTTANNDHTVLSLACAGGHLAVV 676
            AD   +   G T LM A   GH   VQ L+++       T N + T LS+A    H  + 
Sbjct: 1173 ADCNQQDFDGSTALMCACEHGHTAIVQLLLAQPHCDATLTDNENSTALSIAMEASHKDIG 1352

Query: 677  ELLLAH 682
             +L  H
Sbjct: 1353 VILYKH 1370

 Score = 55.8 bits (133), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 44/142 (30%), Positives = 72/142 (50%), Gaps = 5/142 (3%)
 Frame = +3

Query: 1192 VNIIKILLNAGAEINSRTGSKLGISPLMLAAM-----NGHTAAVKLLLDMGSDINAQIET 1246
             +I+ +LL+     + +  +K G +P MLA++     + H   ++ L  +  DINA  E 
Sbjct: 924  FDIVGLLLDTEV-CDVKRPNKAGYTPTMLASLAFIQNDDHRDIIRQLF-LAGDINACAEQ 1097

Query: 1247 NRNTALTLACFQGRTEVVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKGAD 1306
               TAL LA  Q RT++V LLL+  A+   +   G T LM A   G+  + ++LL +   
Sbjct: 1098 TGQTALMLATSQCRTDMVELLLETGADCNQQDFDGSTALMCACEHGHTAIVQLLLAQ-PH 1274

Query: 1307 VNAPPVPSSRDTALTIAADKGH 1328
             +A    +   TAL+IA +  H
Sbjct: 1275 CDATLTDNENSTALSIAMEASH 1340

 Score = 52.4 bits (124), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 53/177 (29%), Positives = 82/177 (46%), Gaps = 7/177 (3%)
 Frame = +3

Query: 243  VNAVRKLLIEGRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGIKGDITPLM 302
            +N +   L+E   VN     G S +    S   +++  +LL        R  K   TP M
Sbjct: 828  INEISHRLLE-YIVNLVDSNGNSAIHYCVSHCNFDIVGLLLDTEVCDVKRPNKAGYTPTM 1004

Query: 303  AAA-----NGGHVKIVK-LLLAHKADVNAQSS-TGNTALTYACAGGYVDVVKVLLESGAS 355
             A+     N  H  I++ L LA   D+NA +  TG TAL  A +    D+V++LLE+GA 
Sbjct: 1005 LASLAFIQNDDHRDIIRQLFLA--GDINACAEQTGQTALMLATSQCRTDMVELLLETGAD 1178

Query: 356  IEDHNENGHTPLMEAGSAGHVEVARLLLENGAGINTHSNEFKESALTLACYKGHLEM 412
                + +G T LM A   GH  + +LLL       T ++    +AL++A    H ++
Sbjct: 1179 CNQQDFDGSTALMCACEHGHTAIVQLLLAQPHCDATLTDNENSTALSIAMEASHKDI 1349

 Score = 52.0 bits (123), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 43/138 (31%), Positives = 69/138 (50%), Gaps = 6/138 (4%)
 Frame = +3

Query: 586  VHATTATGDTALTYACENGHTDVADVLLQAG-ADLEHESEGGRTPLMKAARA-----GHV 639
            V+   + G++A+ Y   + + D+  +LL     D++  ++ G TP M A+ A      H 
Sbjct: 864  VNLVDSNGNSAIHYCVSHCNFDIVGLLLDTEVCDVKRPNKAGYTPTMLASLAFIQNDDHR 1043

Query: 640  CTVQFLISKGANVNRTTANNDHTVLSLACAGGHLAVVELLLAHGADPTHRLKDGSTMLIE 699
              ++ L   G ++N        T L LA +     +VELLL  GAD   +  DGST L+ 
Sbjct: 1044 DIIRQLFLAG-DINACAEQTGQTALMLATSQCRTDMVELLLETGADCNQQDFDGSTALMC 1220

Query: 700  AAKGGHTSVVCYLLDYPN 717
            A + GHT++V  LL  P+
Sbjct: 1221 ACEHGHTAIVQLLLAQPH 1274

 Score = 48.9 bits (115), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 37/127 (29%), Positives = 60/127 (47%), Gaps = 6/127 (4%)
 Frame = +3

Query: 1065 IYPAIDIDAQTESNHDTALTLACAGGHEELVQTLLERGASIEHRDKKGFTPLILAATAGH 1124
            ++ A DI+A  E    TAL LA +    ++V+ LLE GA    +D  G T L+ A   GH
Sbjct: 1059 LFLAGDINACAEQTGQTALMLATSQCRTDMVELLLETGADCNQQDFDGSTALMCACEHGH 1238

Query: 1125 VGVVEILLDNGADIEAQSERTKDTPLSLACSGGRQEVVELLLAR------GANKEHRNVS 1178
              +V++LL         ++    T LS+A     +++  +L         G  K+ ++ S
Sbjct: 1239 TAIVQLLLAQPHCDATLTDNENSTALSIAMEASHKDIGVILYKHLNFSSPGFQKKRKSSS 1418

Query: 1179 DYTPLSL 1185
              TP +L
Sbjct: 1419 SPTPRTL 1439

 Score = 41.6 bits (96), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 27/80 (33%), Positives = 42/80 (52%), Gaps = 1/80 (1%)
 Frame = +3

Query: 440  DGHVEVARLLLDSGAQVNMPAD-SFESPLTLAACGGHVELAALLIERGASLEEVNDEGYT 498
            D H ++ R L  +G  +N  A+ + ++ L LA      ++  LL+E GA   + + +G T
Sbjct: 1032 DDHRDIIRQLFLAG-DINACAEQTGQTALMLATSQCRTDMVELLLETGADCNQQDFDGST 1208

Query: 499  PLMEAAREGHEEMVALLLGQ 518
             LM A   GH  +V LLL Q
Sbjct: 1209 ALMCACEHGHTAIVQLLLAQ 1268

 Score = 39.3 bits (90), Expect = 0.024,   Method: Compositional matrix adjust.
 Identities = 49/200 (24%), Positives = 84/200 (42%), Gaps = 10/200 (5%)
 Frame = +3

Query: 425 HKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALLIE 484
           HK   MH   +E  +    E++  LL+    VN+   +  S +       + ++  LL++
Sbjct: 783 HKLSSMHQ--VEDYLSSINEISHRLLE--YIVNLVDSNGNSAIHYCVSHCNFDIVGLLLD 950

Query: 485 -RGASLEEVNDEGYTPLMEAA-----REGHEEMVALLLGQGANINXXXXXXXXXXXXXXC 538
                ++  N  GYTP M A+      + H +++  L   G +IN               
Sbjct: 951 TEVCDVKRPNKAGYTPTMLASLAFIQNDDHRDIIRQLFLAG-DINACAEQTGQTALMLAT 1127

Query: 539 CGGFLEVADFLIKAGADI---ELGCSTPLMEAAQEGHLELVKYLLAA-GANVHATTATGD 594
                ++ + L++ GAD    +   ST LM A + GH  +V+ LLA    +   T     
Sbjct: 1128SQCRTDMVELLLETGADCNQQDFDGSTALMCACEHGHTAIVQLLLAQPHCDATLTDNENS 1307

Query: 595 TALTYACENGHTDVADVLLQ 614
           TAL+ A E  H D+  +L +
Sbjct: 1308TALSIAMEASHKDIGVILYK 1367
>28494
          Length = 463

 Score = 63.5 bits (153), Expect = 1e-09,   Method: Composition-based stats.
 Identities = 36/87 (41%), Positives = 48/87 (55%)
 Frame = -1

Query: 301 LMAAANGGHVKIVKLLLAHKADVNAQSSTGNTALTYACAGGYVDVVKVLLESGASIEDHN 360
            +AA + G    VK LL   AD+N  +  G TAL  AC    +D+V+ L+E  A ++  +
Sbjct: 307 FLAACSSGDRDEVKKLLERGADINTANVDGLTALHQACIDDNLDMVEFLVEQNADVDVCD 128

Query: 361 ENGHTPLMEAGSAGHVEVARLLLENGA 387
             G TPL    S G  E+AR LLENGA
Sbjct: 127 NEGWTPLHATASCGFTEIARYLLENGA 47

 Score = 53.5 bits (127), Expect = 1e-06,   Method: Composition-based stats.
 Identities = 32/89 (35%), Positives = 48/89 (53%)
 Frame = -1

Query: 1218 LMLAAMNGHTAAVKLLLDMGSDINAQIETNRNTALTLACFQGRTEVVSLLLDRKANVEHR 1277
             + A  +G    VK LL+ G+DIN     +  TAL  AC     ++V  L+++ A+V+  
Sbjct: 307  FLAACSSGDRDEVKKLLERGADINTA-NVDGLTALHQACIDDNLDMVEFLVEQNADVDVC 131

Query: 1278 AKTGLTPLMEAASGGYAEVGRVLLDKGAD 1306
               G TPL   AS G+ E+ R LL+ GA+
Sbjct: 130  DNEGWTPLHATASCGFTEIARYLLENGAN 44

 Score = 52.0 bits (123), Expect = 3e-06,   Method: Composition-based stats.
 Identities = 35/88 (39%), Positives = 49/88 (55%)
 Frame = -1

Query: 367 LMEAGSAGHVEVARLLLENGAGINTHSNEFKESALTLACYKGHLEMVRFLLEAGADQEHK 426
            + A S+G  +  + LLE GA INT +N    +AL  AC   +L+MV FL+E  AD +  
Sbjct: 307 FLAACSSGDRDEVKKLLERGADINT-ANVDGLTALHQACIDDNLDMVEFLVEQNADVDVC 131

Query: 427 TDEMHTALMEACMDGHVEVARLLLDSGA 454
            +E  T L      G  E+AR LL++GA
Sbjct: 130 DNEGWTPLHATASCGFTEIARYLLENGA 47

 Score = 51.2 bits (121), Expect = 5e-06,   Method: Composition-based stats.
 Identities = 35/99 (35%), Positives = 51/99 (51%), Gaps = 6/99 (6%)
 Frame = -1

Query: 1311 PVPSSR-----DTALTIAA-DKGHYKFCELLIGKGAHIDVRNKKGNTPLWLAANGGHLDV 1364
            P PS++     D  + +AA   G     + L+ +GA I+  N  G T L  A    +LD+
Sbjct: 352  PRPSAKKVKFQDGCVFLAACSSGDRDEVKKLLERGADINTANVDGLTALHQACIDDNLDM 173

Query: 1365 VQLLVQATADVDAADNRKITPLMAAFRKGHVKVVRYLVK 1403
            V+ LV+  ADVD  DN   TPL A    G  ++ RYL++
Sbjct: 172  VEFLVEQNADVDVCDNEGWTPLHATASCGFTEIARYLLE 56

 Score = 50.8 bits (120), Expect = 7e-06,   Method: Composition-based stats.
 Identities = 31/95 (32%), Positives = 53/95 (55%), Gaps = 1/95 (1%)
 Frame = -1

Query: 395 EFKESALTLA-CYKGHLEMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSG 453
           +F++  + LA C  G  + V+ LLE GAD      +  TAL +AC+D ++++   L++  
Sbjct: 328 KFQDGCVFLAACSSGDRDEVKKLLERGADINTANVDGLTALHQACIDDNLDMVEFLVEQN 149

Query: 454 AQVNMPADSFESPLTLAACGGHVELAALLIERGAS 488
           A V++  +   +PL   A  G  E+A  L+E GA+
Sbjct: 148 ADVDVCDNEGWTPLHATASCGFTEIARYLLENGAN 44

 Score = 50.4 bits (119), Expect = 1e-05,   Method: Composition-based stats.
 Identities = 31/86 (36%), Positives = 44/86 (51%)
 Frame = -1

Query: 1086 ACAGGHEELVQTLLERGASIEHRDKKGFTPLILAATAGHVGVVEILLDNGADIEAQSERT 1145
            AC+ G  + V+ LLERGA I   +  G T L  A    ++ +VE L++  AD++   +  
Sbjct: 298  ACSSGDRDEVKKLLERGADINTANVDGLTALHQACIDDNLDMVEFLVEQNADVDV-CDNE 122

Query: 1146 KDTPLSLACSGGRQEVVELLLARGAN 1171
              TPL    S G  E+   LL  GAN
Sbjct: 121  GWTPLHATASCGFTEIARYLLENGAN 44

 Score = 49.7 bits (117), Expect = 2e-05,   Method: Composition-based stats.
 Identities = 30/93 (32%), Positives = 46/93 (49%)
 Frame = -1

Query: 559 GCSTPLMEAAQEGHLELVKYLLAAGANVHATTATGDTALTYACENGHTDVADVLLQAGAD 618
           GC    + A   G  + VK LL  GA+++     G TAL  AC + + D+ + L++  AD
Sbjct: 316 GCV--FLAACSSGDRDEVKKLLERGADINTANVDGLTALHQACIDDNLDMVEFLVEQNAD 143

Query: 619 LEHESEGGRTPLMKAARAGHVCTVQFLISKGAN 651
           ++     G TPL   A  G     ++L+  GAN
Sbjct: 142 VDVCDNEGWTPLHATASCGFTEIARYLLENGAN 44

 Score = 48.1 bits (113), Expect = 4e-05,   Method: Composition-based stats.
 Identities = 32/87 (36%), Positives = 47/87 (54%), Gaps = 1/87 (1%)
 Frame = -1

Query: 337 ACAGGYVDVVKVLLESGASIEDHNENGHTPLMEAGSAGHVEVARLLLENGAGINTHSNE- 395
           AC+ G  D VK LLE GA I   N +G T L +A    ++++   L+E  A ++   NE 
Sbjct: 298 ACSSGDRDEVKKLLERGADINTANVDGLTALHQACIDDNLDMVEFLVEQNADVDVCDNEG 119

Query: 396 FKESALTLACYKGHLEMVRFLLEAGAD 422
           +     T +C  G  E+ R+LLE GA+
Sbjct: 118 WTPLHATASC--GFTEIARYLLENGAN 44

 Score = 46.6 bits (109), Expect = 1e-04,   Method: Composition-based stats.
 Identities = 26/88 (29%), Positives = 44/88 (50%)
 Frame = -1

Query: 434 LMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALLIERGASLEEVN 493
            + AC  G  +  + LL+ GA +N       + L  A    ++++   L+E+ A ++  +
Sbjct: 307 FLAACSSGDRDEVKKLLERGADINTANVDGLTALHQACIDDNLDMVEFLVEQNADVDVCD 128

Query: 494 DEGYTPLMEAAREGHEEMVALLLGQGAN 521
           +EG+TPL   A  G  E+   LL  GAN
Sbjct: 127 NEGWTPLHATASCGFTEIARYLLENGAN 44

 Score = 44.3 bits (103), Expect = 6e-04,   Method: Composition-based stats.
 Identities = 29/86 (33%), Positives = 47/86 (54%)
 Frame = -1

Query: 237 ACSEGDVNAVRKLLIEGRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGIKG 296
           ACS GD + V+KLL  G  +N    +G + L  AC     ++ + L+  +A+V+    +G
Sbjct: 298 ACSSGDRDEVKKLLERGADINTANVDGLTALHQACIDDNLDMVEFLVEQNADVDVCDNEG 119

Query: 297 DITPLMAAANGGHVKIVKLLLAHKAD 322
             TPL A A+ G  +I + LL + A+
Sbjct: 118 -WTPLHATASCGFTEIARYLLENGAN 44

 Score = 43.1 bits (100), Expect = 0.002,   Method: Composition-based stats.
 Identities = 22/64 (34%), Positives = 38/64 (59%)
 Frame = -1

Query: 1081 TALTLACAGGHEELVQTLLERGASIEHRDKKGFTPLILAATAGHVGVVEILLDNGADIEA 1140
            TAL  AC   + ++V+ L+E+ A ++  D +G+TPL   A+ G   +   LL+NGA+   
Sbjct: 214  TALHQACIDDNLDMVEFLVEQNADVDVCDNEGWTPLHATASCGFTEIARYLLENGANGGC 35

Query: 1141 QSER 1144
            + +R
Sbjct: 34   RQQR 23

 Score = 40.8 bits (94), Expect = 0.007,   Method: Composition-based stats.
 Identities = 25/86 (29%), Positives = 46/86 (53%)
 Frame = -1

Query: 270 ACSAGYYELAQVLLAMHANVEDRGIKGDITPLMAAANGGHVKIVKLLLAHKADVNAQSST 329
           ACS+G  +  + LL   A++    + G +T L  A    ++ +V+ L+   ADV+   + 
Sbjct: 298 ACSSGDRDEVKKLLERGADINTANVDG-LTALHQACIDDNLDMVEFLVEQNADVDVCDNE 122

Query: 330 GNTALTYACAGGYVDVVKVLLESGAS 355
           G T L    + G+ ++ + LLE+GA+
Sbjct: 121 GWTPLHATASCGFTEIARYLLENGAN 44

 Score = 40.0 bits (92), Expect = 0.012,   Method: Composition-based stats.
 Identities = 28/90 (31%), Positives = 42/90 (46%), Gaps = 4/90 (4%)
 Frame = -1

Query: 500 LMEAAREGHEEMVALLLGQGANINXXXXXXXXXXXXXXCCGGFLEVADFLIKAGADIELG 559
            + A   G  + V  LL +GA+IN              C    L++ +FL++  AD+++ 
Sbjct: 307 FLAACSSGDRDEVKKLLERGADINTANVDGLTALHQA-CIDDNLDMVEFLVEQNADVDV- 134

Query: 560 CS----TPLMEAAQEGHLELVKYLLAAGAN 585
           C     TPL   A  G  E+ +YLL  GAN
Sbjct: 133 CDNEGWTPLHATASCGFTEIARYLLENGAN 44

 Score = 40.0 bits (92), Expect = 0.013,   Method: Composition-based stats.
 Identities = 30/96 (31%), Positives = 49/96 (51%)
 Frame = -1

Query: 1279 KTGLTPLMEAASGGYAEVGRVLLDKGADVNAPPVPSSRDTALTIAADKGHYKFCELLIGK 1338
            + G   L   +SG   EV + LL++GAD+N   V     TAL  A    +    E L+ +
Sbjct: 322  QDGCVFLAACSSGDRDEVKK-LLERGADINTANVDGL--TALHQACIDDNLDMVEFLVEQ 152

Query: 1339 GAHIDVRNKKGNTPLWLAANGGHLDVVQLLVQATAD 1374
             A +DV + +G TPL   A+ G  ++ + L++  A+
Sbjct: 151  NADVDVCDNEGWTPLHATASCGFTEIARYLLENGAN 44

 Score = 38.9 bits (89), Expect = 0.026,   Method: Composition-based stats.
 Identities = 26/87 (29%), Positives = 44/87 (50%)
 Frame = -1

Query: 1153 ACSGGRQEVVELLLARGANKEHRNVSDYTPLSLAASGGYVNIIKILLNAGAEINSRTGSK 1212
            ACS G ++ V+ LL RGA+    NV   T L  A     +++++ L+   A+++      
Sbjct: 298  ACSSGDRDEVKKLLERGADINTANVDGLTALHQACIDDNLDMVEFLVEQNADVD--VCDN 125

Query: 1213 LGISPLMLAAMNGHTAAVKLLLDMGSD 1239
             G +PL   A  G T   + LL+ G++
Sbjct: 124  EGWTPLHATASCGFTEIARYLLENGAN 44

 Score = 38.9 bits (89), Expect = 0.030,   Method: Composition-based stats.
 Identities = 29/99 (29%), Positives = 45/99 (45%), Gaps = 9/99 (9%)
 Frame = -1

Query: 600 ACENGHTDVADVLLQAGADLEHESEGGRTPLMKAARAGHVCTVQFLISKGANVNRTTANN 659
           AC +G  D    LL+ GAD+   +  G T L +A    ++  V+FL+ + A+V+    N 
Sbjct: 298 ACSSGDRDEVKKLLERGADINTANVDGLTALHQACIDDNLDMVEFLVEQNADVD-VCDNE 122

Query: 660 DHTVLSLACAGGHLAVVELLLAHGAD---------PTHR 689
             T L    + G   +   LL +GA+         P HR
Sbjct: 121 GWTPLHATASCGFTEIARYLLENGANGGCRQQRWGPCHR 5
>25470
          Length = 400

 Score = 62.0 bits (149), Expect = 3e-09,   Method: Composition-based stats.
 Identities = 46/108 (42%), Positives = 59/108 (54%), Gaps = 4/108 (3%)
 Frame = -3

Query: 1253 TLACFQGRTEVVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADVNAPPV 1312
            +LA   GR +VV  LL+  ANV  R   GL PL  A S G+AEV ++LL  GAD      
Sbjct: 383  SLAAGFGRKDVVEHLLENGANVHARDDGGLIPLHNACSFGHAEVVQLLLRHGAD------ 222

Query: 1313 PSSRD----TALTIAADKGHYKFCELLIGKGAHIDVRNKKGNTPLWLA 1356
            P++RD    T L  AA KG    C +L+ + A  ++RN  G T L LA
Sbjct: 221  PNARDNWNYTPLHEAAIKGKIDVCIVLLQQCADPNIRNTDGKTALDLA 78

 Score = 60.8 bits (146), Expect = 6e-09,   Method: Composition-based stats.
 Identities = 40/91 (43%), Positives = 54/91 (59%)
 Frame = -3

Query: 1118 LAATAGHVGVVEILLDNGADIEAQSERTKDTPLSLACSGGRQEVVELLLARGANKEHRNV 1177
            LAA  G   VVE LL+NGA++ A+ +     PL  ACS G  EVV+LLL  GA+   R+ 
Sbjct: 380  LAAGFGRKDVVEHLLENGANVHARDDGGL-IPLHNACSFGHAEVVQLLLRHGADPNARDN 204

Query: 1178 SDYTPLSLAASGGYVNIIKILLNAGAEINSR 1208
             +YTPL  AA  G +++  +LL   A+ N R
Sbjct: 203  WNYTPLHEAAIKGKIDVCIVLLQQCADPNIR 111

 Score = 60.5 bits (145), Expect = 9e-09,   Method: Composition-based stats.
 Identities = 40/103 (38%), Positives = 58/103 (56%)
 Frame = -3

Query: 1084 TLACAGGHEELVQTLLERGASIEHRDKKGFTPLILAATAGHVGVVEILLDNGADIEAQSE 1143
            +LA   G +++V+ LLE GA++  RD  G  PL  A + GH  VV++LL +GAD  A+ +
Sbjct: 383  SLAAGFGRKDVVEHLLENGANVHARDDGGLIPLHNACSFGHAEVVQLLLRHGADPNAR-D 207

Query: 1144 RTKDTPLSLACSGGRQEVVELLLARGANKEHRNVSDYTPLSLA 1186
                TPL  A   G+ +V  +LL + A+   RN    T L LA
Sbjct: 206  NWNYTPLHEAAIKGKIDVCIVLLQQCADPNIRNTDGKTALDLA 78

 Score = 55.5 bits (132), Expect = 3e-07,   Method: Composition-based stats.
 Identities = 42/109 (38%), Positives = 59/109 (54%)
 Frame = -3

Query: 1147 DTPLSLACSGGRQEVVELLLARGANKEHRNVSDYTPLSLAASGGYVNIIKILLNAGAEIN 1206
            +TP SLA   GR++VVE LL  GAN   R+     PL  A S G+  ++++LL  GA+ N
Sbjct: 392  NTP-SLAAGFGRKDVVEHLLENGANVHARDDGGLIPLHNACSFGHAEVVQLLLRHGADPN 216

Query: 1207 SRTGSKLGISPLMLAAMNGHTAAVKLLLDMGSDINAQIETNRNTALTLA 1255
            +R       +PL  AA+ G      +LL   +D N +  T+  TAL LA
Sbjct: 215  AR--DNWNYTPLHEAAIKGKIDVCIVLLQQCADPNIR-NTDGKTALDLA 78

 Score = 53.5 bits (127), Expect = 1e-06,   Method: Composition-based stats.
 Identities = 38/99 (38%), Positives = 51/99 (51%)
 Frame = -3

Query: 269 LACSAGYYELAQVLLAMHANVEDRGIKGDITPLMAAANGGHVKIVKLLLAHKADVNAQSS 328
           LA   G  ++ + LL   ANV  R   G + PL  A + GH ++V+LLL H AD NA+ +
Sbjct: 380 LAAGFGRKDVVEHLLENGANVHARD-DGGLIPLHNACSFGHAEVVQLLLRHGADPNARDN 204

Query: 329 TGNTALTYACAGGYVDVVKVLLESGASIEDHNENGHTPL 367
              T L  A   G +DV  VLL+  A     N +G T L
Sbjct: 203 WNYTPLHEAAIKGKIDVCIVLLQQCADPNIRNTDGKTAL 87

 Score = 52.0 bits (123), Expect = 3e-06,   Method: Composition-based stats.
 Identities = 38/106 (35%), Positives = 59/106 (55%)
 Frame = -3

Query: 299 TPLMAAANGGHVKIVKLLLAHKADVNAQSSTGNTALTYACAGGYVDVVKVLLESGASIED 358
           TP +AA  G    +V+ LL + A+V+A+   G   L  AC+ G+ +VV++LL  GA    
Sbjct: 389 TPSLAAGFG-RKDVVEHLLENGANVHARDDGGLIPLHNACSFGHAEVVQLLLRHGADPNA 213

Query: 359 HNENGHTPLMEAGSAGHVEVARLLLENGAGINTHSNEFKESALTLA 404
            +   +TPL EA   G ++V  +LL+  A  N  + + K +AL LA
Sbjct: 212 RDNWNYTPLHEAAIKGKIDVCIVLLQQCADPNIRNTDGK-TALDLA 78

 Score = 52.0 bits (123), Expect = 3e-06,   Method: Composition-based stats.
 Identities = 42/110 (38%), Positives = 57/110 (51%), Gaps = 1/110 (0%)
 Frame = -3

Query: 561 STPLMEAAQEGHLELVKYLLAAGANVHATTATGDTALTYACENGHTDVADVLLQAGADLE 620
           +TP + AA  G  ++V++LL  GANVHA    G   L  AC  GH +V  +LL+ GAD  
Sbjct: 392 NTPSL-AAGFGRKDVVEHLLENGANVHARDDGGLIPLHNACSFGHAEVVQLLLRHGADPN 216

Query: 621 HESEGGRTPLMKAARAGHVCTVQFLISKGANVN-RTTANNDHTVLSLACA 669
                  TPL +AA  G +     L+ + A+ N R T  +  T L LA A
Sbjct: 215 ARDNWNYTPLHEAAIKGKIDVCIVLLQQCADPNIRNT--DGKTALDLADA 72

 Score = 51.2 bits (121), Expect = 5e-06,   Method: Composition-based stats.
 Identities = 32/84 (38%), Positives = 47/84 (55%)
 Frame = -3

Query: 1321 TIAADKGHYKFCELLIGKGAHIDVRNKKGNTPLWLAANGGHLDVVQLLVQATADVDAADN 1380
            ++AA  G     E L+  GA++  R+  G  PL  A + GH +VVQLL++  AD +A DN
Sbjct: 383  SLAAGFGRKDVVEHLLENGANVHARDDGGLIPLHNACSFGHAEVVQLLLRHGADPNARDN 204

Query: 1381 RKITPLMAAFRKGHVKVVRYLVKE 1404
               TPL  A  KG + V   L+++
Sbjct: 203  WNYTPLHEAAIKGKIDVCIVLLQQ 132

 Score = 48.9 bits (115), Expect = 3e-05,   Method: Composition-based stats.
 Identities = 37/107 (34%), Positives = 56/107 (52%)
 Frame = -3

Query: 364 HTPLMEAGSAGHVEVARLLLENGAGINTHSNEFKESALTLACYKGHLEMVRFLLEAGADQ 423
           +TP + AG  G  +V   LLENGA ++   ++     L  AC  GH E+V+ LL  GAD 
Sbjct: 392 NTPSLAAG-FGRKDVVEHLLENGANVHAR-DDGGLIPLHNACSFGHAEVVQLLLRHGADP 219

Query: 424 EHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLA 470
             + +  +T L EA + G ++V  +LL   A  N+     ++ L LA
Sbjct: 218 NARDNWNYTPLHEAAIKGKIDVCIVLLQQCADPNIRNTDGKTALDLA 78

 Score = 47.8 bits (112), Expect = 6e-05,   Method: Composition-based stats.
 Identities = 34/99 (34%), Positives = 50/99 (50%)
 Frame = -3

Query: 402 TLACYKGHLEMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPAD 461
           +LA   G  ++V  LLE GA+   + D     L  AC  GH EV +LLL  GA  N   +
Sbjct: 383 SLAAGFGRKDVVEHLLENGANVHARDDGGLIPLHNACSFGHAEVVQLLLRHGADPNARDN 204

Query: 462 SFESPLTLAACGGHVELAALLIERGASLEEVNDEGYTPL 500
              +PL  AA  G +++  +L+++ A     N +G T L
Sbjct: 203 WNYTPLHEAAIKGKIDVCIVLLQQCADPNIRNTDGKTAL 87

 Score = 47.0 bits (110), Expect = 9e-05,   Method: Composition-based stats.
 Identities = 31/83 (37%), Positives = 44/83 (53%)
 Frame = -3

Query: 441 GHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALLIERGASLEEVNDEGYTPL 500
           G  +V   LL++GA V+   D    PL  A   GH E+  LL+  GA     ++  YTPL
Sbjct: 365 GRKDVVEHLLENGANVHARDDGGLIPLHNACSFGHAEVVQLLLRHGADPNARDNWNYTPL 186

Query: 501 MEAAREGHEEMVALLLGQGANIN 523
            EAA +G  ++  +LL Q A+ N
Sbjct: 185 HEAAIKGKIDVCIVLLQQCADPN 117

 Score = 47.0 bits (110), Expect = 9e-05,   Method: Composition-based stats.
 Identities = 36/83 (43%), Positives = 44/83 (53%), Gaps = 2/83 (2%)
 Frame = -3

Query: 633 AARAGHVCTVQFLISKGANVNRTTANNDHTVLSL--ACAGGHLAVVELLLAHGADPTHRL 690
           AA  G    V+ L+  GANV+   A +D  ++ L  AC+ GH  VV+LLL HGADP  R 
Sbjct: 377 AAGFGRKDVVEHLLENGANVH---ARDDGGLIPLHNACSFGHAEVVQLLLRHGADPNARD 207

Query: 691 KDGSTMLIEAAKGGHTSVVCYLL 713
               T L EAA  G   V   LL
Sbjct: 206 NWNYTPLHEAAIKGKIDVCIVLL 138

 Score = 43.9 bits (102), Expect = 0.001,   Method: Composition-based stats.
 Identities = 39/107 (36%), Positives = 53/107 (49%)
 Frame = -3

Query: 233 SLAEACSEGDVNAVRKLLIEGRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDR 292
           SLA      DV  V  LL  G +V+   + G   L  ACS G+ E+ Q+LL   A+   R
Sbjct: 383 SLAAGFGRKDV--VEHLLENGANVHARDDGGLIPLHNACSFGHAEVVQLLLRHGADPNAR 210

Query: 293 GIKGDITPLMAAANGGHVKIVKLLLAHKADVNAQSSTGNTALTYACA 339
               + TPL  AA  G + +  +LL   AD N +++ G TAL  A A
Sbjct: 209 D-NWNYTPLHEAAIKGKIDVCIVLLQQCADPNIRNTDGKTALDLADA 72

 Score = 40.8 bits (94), Expect = 0.006,   Method: Composition-based stats.
 Identities = 38/133 (28%), Positives = 53/133 (39%)
 Frame = -3

Query: 468 TLAACGGHVELAALLIERGASLEEVNDEGYTPLMEAAREGHEEMVALLLGQGANINXXXX 527
           +LAA  G  ++   L+E GA++   +D G  PL  A   GH E+V LLL  GA+ N    
Sbjct: 383 SLAAGFGRKDVVEHLLENGANVHARDDGGLIPLHNACSFGHAEVVQLLLRHGADPNARDN 204

Query: 528 XXXXXXXXXXCCGGFLEVADFLIKAGADIELGCSTPLMEAAQEGHLELVKYLLAAGANVH 587
                                             TPL EAA +G +++   LL   A+ +
Sbjct: 203 WNY-------------------------------TPLHEAAIKGKIDVCIVLLQQCADPN 117

Query: 588 ATTATGDTALTYA 600
                G TAL  A
Sbjct: 116 IRNTDGKTALDLA 78
>02055
          Length = 1740

 Score = 62.0 bits (149), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 76/317 (23%), Positives = 126/317 (39%), Gaps = 6/317 (1%)
 Frame = +3

Query: 1095 VQTLLERGASIEHRDKKGFTPLILAATAGHVGVVEILLDNGADIEAQSERTKDTPLSLAC 1154
            V  L+  GA ++  +  G TPL +A    +   +  L+ NGA++ A+++    TPL +AC
Sbjct: 372  VDDLIRCGADVDFCNMFGDTPLHIATVHANHEAMGALVRNGANVNARAKFLNSTPLHVAC 551

Query: 1155 SGGRQEVVELLLARGANKEHRNVSDYTPLSLAASGGYVNIIKILLNAGAEI-NSRTGSKL 1213
                Q+ V LL+  GA  +  + +  TPL +A       ++ ILL +   I  +   +KL
Sbjct: 552  RLRGQQEVALLIQLGARIDVNDATGTTPLQMACKRADPAVVNILLRSQPSIVRTEDANKL 731

Query: 1214 GISPLMLAAMNGHTAAVKLLLDMGSDINAQIET-----NRNTALTLACFQGRTEVVSLLL 1268
                   A        VK+L + G  +N +  T       N A  +A F         + 
Sbjct: 732  ----FKYAIQKRQLHIVKMLCEAGVAVNYEGTTPVHIAMDNQAWDIAKF--------FIT 875

Query: 1269 DRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADVNAPPVPSSRDTALTIAADKGH 1328
              K N + R   G TPL  A            L  GAD                      
Sbjct: 876  SNKHNFDGRDSKGRTPLCLA------------LLSGAD---------------------- 953

Query: 1329 YKFCELLIGKGAHIDVRNKKGNTPLWLAANGGHLDVVQLLVQATADVDAADNRKITPLMA 1388
            +     L+  G  ID  +  G T L  A      ++V  +++   +V A +   +  ++ 
Sbjct: 954  FHMVSFLLNVGYSIDQVDSNGETWLLRAGRQNEENLVCSILRFNPNVYAPNRYNVPLVLE 1133

Query: 1389 AFRKGHVKVVRYLVKEV 1405
             F KGH  +V +LV+++
Sbjct: 1134 LFDKGHYAIVNHLVRKI 1184

 Score = 52.4 bits (124), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 76/309 (24%), Positives = 118/309 (38%), Gaps = 11/309 (3%)
 Frame = +3

Query: 225 NAGQSDNRS---------LAEACSEGDVNAVRKLLIEGRSVNEHTEEGESLLCLACSAGY 275
           +A QS +RS         L EA        V  L+  G  V+     G++ L +A     
Sbjct: 282 DADQSTDRSVEEFELKKDLCEAVQRVCAREVDDLIRCGADVDFCNMFGDTPLHIATVHAN 461

Query: 276 YELAQVLLAMHANVEDRGIKGDITPLMAAANGGHVKIVKLLLAHKADVNAQSSTGNTALT 335
           +E    L+   ANV  R    + TPL  A      + V LL+   A ++   +TG T L 
Sbjct: 462 HEAMGALVRNGANVNARAKFLNSTPLHVACRLRGQQEVALLIQLGARIDVNDATGTTPLQ 641

Query: 336 YACAGGYVDVVKVLLESGASIEDHNENGHTPLMEAGSAGHVEVARLLLENGAGINTHSNE 395
            AC      VV +LL S  SI    E+ +     A     + + ++L E G  +N     
Sbjct: 642 MACKRADPAVVNILLRSQPSIV-RTEDANKLFKYAIQKRQLHIVKMLCEAGVAVN----- 803

Query: 396 FKESALTLACYKGHLEMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQ 455
                     Y+G                  T  +H A+     D    +A+  + S   
Sbjct: 804 ----------YEG------------------TTPVHIAMDNQAWD----IAKFFITSNKH 887

Query: 456 VNMPADSF-ESPLTLAAC-GGHVELAALLIERGASLEEVNDEGYTPLMEAAREGHEEMVA 513
                DS   +PL LA   G    + + L+  G S+++V+  G T L+ A R+  E +V 
Sbjct: 888 NFDGRDSKGRTPLCLALLSGADFHMVSFLLNVGYSIDQVDSNGETWLLRAGRQNEENLVC 1067

Query: 514 LLLGQGANI 522
            +L    N+
Sbjct: 1068SILRFNPNV 1094

 Score = 48.9 bits (115), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 62/237 (26%), Positives = 104/237 (43%), Gaps = 3/237 (1%)
 Frame = +3

Query: 1070 DIDAQTESNHDTALTLACAGGHEELVQTLLERGASIEHRDKKGFTPLILAATAGHVGVVE 1129
            +++A+ +  + T L +AC    ++ V  L++ GA I+  D  G TPL +A       VV 
Sbjct: 498  NVNARAKFLNSTPLHVACRLRGQQEVALLIQLGARIDVNDATGTTPLQMACKRADPAVVN 677

Query: 1130 ILLDNGADIEAQSERTKDTP--LSLACSGGRQEVVELLLARGANKEHRNVSDYTPLSLAA 1187
            ILL +   I     RT+D       A    +  +V++L   G      N    TP+ +A 
Sbjct: 678  ILLRSQPSI----VRTEDANKLFKYAIQKRQLHIVKMLCEAGVAV---NYEGTTPVHIAM 836

Query: 1188 SGGYVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNG-HTAAVKLLLDMGSDINAQIET 1246
                 +I K  + +         SK G +PL LA ++G     V  LL++G  I+ Q+++
Sbjct: 837  DNQAWDIAKFFITSNKHNFDGRDSK-GRTPLCLALLSGADFHMVSFLLNVGYSID-QVDS 1010

Query: 1247 NRNTALTLACFQGRTEVVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDK 1303
            N  T L  A  Q    +V  +L    NV    +  +  ++E    G+  +   L+ K
Sbjct: 1011 NGETWLLRAGRQNEENLVCSILRFNPNVYAPNRYNVPLVLELFDKGHYAIVNHLVRK 1181

 Score = 43.5 bits (101), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 59/247 (23%), Positives = 92/247 (37%), Gaps = 4/247 (1%)
 Frame = +3

Query: 346 VKVLLESGASIEDHNENGHTPLMEAGSAGHVEVARLLLENGAGINTHSNEFKESALTLAC 405
           V  L+  GA ++  N  G TPL  A    + E    L+ NGA +N  +     + L +AC
Sbjct: 372 VDDLIRCGADVDFCNMFGDTPLHIATVHANHEAMGALVRNGANVNARAKFLNSTPLHVAC 551

Query: 406 YKGHLEMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFES 465
                + V  L++ GA  +       T L  AC      V  +LL S   +    D+   
Sbjct: 552 RLRGQQEVALLIQLGARIDVNDATGTTPLQMACKRADPAVVNILLRSQPSIVRTEDA-NK 728

Query: 466 PLTLAACGGHVELAALLIERGASLEEVNDEGYTPLMEAAREGHEEMVALLLGQGA-NINX 524
               A     + +  +L E G +   VN EG TP+  A      ++    +     N + 
Sbjct: 729 LFKYAIQKRQLHIVKMLCEAGVA---VNYEGTTPVHIAMDNQAWDIAKFFITSNKHNFDG 899

Query: 525 XXXXXXXXXXXXXCCGGFLEVADFLIKAGADIELGCS---TPLMEAAQEGHLELVKYLLA 581
                          G    +  FL+  G  I+   S   T L+ A ++    LV  +L 
Sbjct: 900 RDSKGRTPLCLALLSGADFHMVSFLLNVGYSIDQVDSNGETWLLRAGRQNEENLVCSILR 1079

Query: 582 AGANVHA 588
              NV+A
Sbjct: 1080FNPNVYA 1100

 Score = 42.7 bits (99), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 68/274 (24%), Positives = 99/274 (36%), Gaps = 34/274 (12%)
 Frame = +3

Query: 482 LIERGASLEEVNDEGYTPLMEAAREGHEEMVALLLGQGANINXXXXXXXXXXXXXXCCGG 541
           LI  GA ++  N  G TPL  A    + E +  L+  GAN+N                  
Sbjct: 381 LIRCGADVDFCNMFGDTPLHIATVHANHEAMGALVRNGANVNAR---------------- 512

Query: 542 FLEVADFLIKAGADIELGCSTPLMEAAQEGHLELVKYLLAAGANVHATTATGDTALTYAC 601
               A FL           STPL  A +    + V  L+  GA +    ATG T L  AC
Sbjct: 513 ----AKFL----------NSTPLHVACRLRGQQEVALLIQLGARIDVNDATGTTPLQMAC 650

Query: 602 ENGHTDVADVLLQAGADLEHESEGGRTPLMKAA---RAGHVCTVQFLISKGANVNRT--- 655
           +     V ++LL++   +    +  +  L K A   R  H+  V+ L   G  VN     
Sbjct: 651 KRADPAVVNILLRSQPSIVRTEDANK--LFKYAIQKRQLHI--VKMLCEAGVAVNYEGTT 818

Query: 656 -----------------TANNDH----------TVLSLA-CAGGHLAVVELLLAHGADPT 687
                              +N H          T L LA  +G    +V  LL  G    
Sbjct: 819 PVHIAMDNQAWDIAKFFITSNKHNFDGRDSKGRTPLCLALLSGADFHMVSFLLNVGYSID 998

Query: 688 HRLKDGSTMLIEAAKGGHTSVVCYLLDYPNNLLA 721
               +G T L+ A +    ++VC +L +  N+ A
Sbjct: 999 QVDSNGETWLLRAGRQNEENLVCSILRFNPNVYA 1100

 Score = 42.4 bits (98), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 44/145 (30%), Positives = 65/145 (44%), Gaps = 6/145 (4%)
 Frame = +3

Query: 546 ADFLIKAGADIELGCS----TPLMEAAQEGHLELVKYLLAAGANVHATTA-TGDTALTYA 600
            D LI+ GAD++  C+    TPL  A    + E +  L+  GANV+A       T L  A
Sbjct: 372 VDDLIRCGADVDF-CNMFGDTPLHIATVHANHEAMGALVRNGANVNARAKFLNSTPLHVA 548

Query: 601 CE-NGHTDVADVLLQAGADLEHESEGGRTPLMKAARAGHVCTVQFLISKGANVNRTTANN 659
           C   G  +VA +L+Q GA ++     G TPL  A +      V  L+    ++ RT   N
Sbjct: 549 CRLRGQQEVA-LLIQLGARIDVNDATGTTPLQMACKRADPAVVNILLRSQPSIVRTEDAN 725

Query: 660 DHTVLSLACAGGHLAVVELLLAHGA 684
              +   A     L +V++L   G 
Sbjct: 726 --KLFKYAIQKRQLHIVKMLCEAGV 794

 Score = 32.3 bits (72), Expect = 2.5,   Method: Compositional matrix adjust.
 Identities = 34/105 (32%), Positives = 47/105 (44%)
 Frame = +3

Query: 609 ADVLLQAGADLEHESEGGRTPLMKAARAGHVCTVQFLISKGANVNRTTANNDHTVLSLAC 668
            D L++ GAD++  +  G TPL  A    +   +  L+  GANVN      + T L +AC
Sbjct: 372 VDDLIRCGADVDFCNMFGDTPLHIATVHANHEAMGALVRNGANVNARAKFLNSTPLHVAC 551

Query: 669 AGGHLAVVELLLAHGADPTHRLKDGSTMLIEAAKGGHTSVVCYLL 713
                  V LL+  GA        G+T L  A K    +VV  LL
Sbjct: 552 RLRGQQEVALLIQLGARIDVNDATGTTPLQMACKRADPAVVNILL 686
>21532
          Length = 460

 Score = 58.5 bits (140), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 37/114 (32%), Positives = 57/114 (50%), Gaps = 6/114 (5%)
 Frame = -1

Query: 1094 LVQTLLERGASIEHRDKKGFTPLILAATAGHVGVVEILLDNGAD------IEAQSERTKD 1147
            ++ TLL  GA +  RD  G TP   A   G++  V+ LL  G        +    + +++
Sbjct: 451  IINTLLSHGADVNIRDNTGCTPFANACCLGNLAAVKALLTPGESPSWSKPMINVRDNSQN 272

Query: 1148 TPLSLACSGGRQEVVELLLARGANKEHRNVSDYTPLSLAASGGYVNIIKILLNA 1201
            TPL LA   G   +VELL+   A+   +N S + PLSLA    + N++ +L  A
Sbjct: 271  TPLHLASQEGHTAIVELLVEHKADLAAKNDSGHNPLSLARQYKHENVVAVLQQA 110

 Score = 55.1 bits (131), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 36/111 (32%), Positives = 54/111 (48%), Gaps = 7/111 (6%)
 Frame = -1

Query: 412 MVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGA-------QVNMPADSFE 464
           ++  LL  GAD   + +   T    AC  G++   + LL  G         +N+  +S  
Sbjct: 451 IINTLLSHGADVNIRDNTGCTPFANACCLGNLAAVKALLTPGESPSWSKPMINVRDNSQN 272

Query: 465 SPLTLAACGGHVELAALLIERGASLEEVNDEGYTPLMEAAREGHEEMVALL 515
           +PL LA+  GH  +  LL+E  A L   ND G+ PL  A +  HE +VA+L
Sbjct: 271 TPLHLASQEGHTAIVELLVEHKADLAAKNDSGHNPLSLARQYKHENVVAVL 119

 Score = 53.9 bits (128), Expect = 9e-07,   Method: Compositional matrix adjust.
 Identities = 41/119 (34%), Positives = 59/119 (49%), Gaps = 9/119 (7%)
 Frame = -1

Query: 310 VKIVKLLLAHKADVNAQSSTGNTALTYACAGGYVDVVKVLLESGAS---------IEDHN 360
           V I+  LL+H ADVN + +TG T    AC  G +  VK LL  G S         + D++
Sbjct: 457 VPIINTLLSHGADVNIRDNTGCTPFANACCLGNLAAVKALLTPGESPSWSKPMINVRDNS 278

Query: 361 ENGHTPLMEAGSAGHVEVARLLLENGAGINTHSNEFKESALTLACYKGHLEMVRFLLEA 419
           +N  TPL  A   GH  +  LL+E+ A +    N+   + L+LA    H  +V  L +A
Sbjct: 277 QN--TPLHLASQEGHTAIVELLVEHKADL-AAKNDSGHNPLSLARQYKHENVVAVLQQA 110

 Score = 49.7 bits (117), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 44/155 (28%), Positives = 63/155 (40%), Gaps = 3/155 (1%)
 Frame = -1

Query: 1263 VVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADVNAPPVPSSRDTALTI 1322
            +++ LL   A+V  R  TG TP   A   G     + LL  G        PS        
Sbjct: 451  IINTLLSHGADVNIRDNTGCTPFANACCLGNLAAVKALLTPGES------PSWSKPM--- 299

Query: 1323 AADKGHYKFCELLIGKGAHIDVRNKKGNTPLWLAANGGHLDVVQLLVQATADVDAADNRK 1382
                               I+VR+   NTPL LA+  GH  +V+LLV+  AD+ A ++  
Sbjct: 298  -------------------INVRDNSQNTPLHLASQEGHTAIVELLVEHKADLAAKNDSG 176

Query: 1383 ITPLMAAFRKGHVKVVRYLVKEVNQ---FPSDSEC 1414
              PL  A +  H  VV  L +  N     P++ +C
Sbjct: 175  HNPLSLARQYKHENVVAVLQQAENTEPVIPTNYDC 71

 Score = 45.8 bits (107), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 35/111 (31%), Positives = 52/111 (46%), Gaps = 6/111 (5%)
 Frame = -1

Query: 608 VADVLLQAGADLEHESEGGRTPLMKAARAGHVCTVQFLISKGAN------VNRTTANNDH 661
           + + LL  GAD+      G TP   A   G++  V+ L++ G +      +     N+ +
Sbjct: 451 IINTLLSHGADVNIRDNTGCTPFANACCLGNLAAVKALLTPGESPSWSKPMINVRDNSQN 272

Query: 662 TVLSLACAGGHLAVVELLLAHGADPTHRLKDGSTMLIEAAKGGHTSVVCYL 712
           T L LA   GH A+VELL+ H AD   +   G   L  A +  H +VV  L
Sbjct: 271 TPLHLASQEGHTAIVELLVEHKADLAAKNDSGHNPLSLARQYKHENVVAVL 119

 Score = 44.3 bits (103), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 33/112 (29%), Positives = 54/112 (48%), Gaps = 11/112 (9%)
 Frame = -1

Query: 545 VADFLIKAGADIEL----GCSTPLMEAAQEGHLELVKYLLAAGAN-------VHATTATG 593
           + + L+  GAD+ +    GC TP   A   G+L  VK LL  G +       ++    + 
Sbjct: 451 IINTLLSHGADVNIRDNTGC-TPFANACCLGNLAAVKALLTPGESPSWSKPMINVRDNSQ 275

Query: 594 DTALTYACENGHTDVADVLLQAGADLEHESEGGRTPLMKAARAGHVCTVQFL 645
           +T L  A + GHT + ++L++  ADL  +++ G  PL  A +  H   V  L
Sbjct: 274 NTPLHLASQEGHTAIVELLVEHKADLAAKNDSGHNPLSLARQYKHENVVAVL 119

 Score = 43.1 bits (100), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 37/120 (30%), Positives = 54/120 (45%), Gaps = 9/120 (7%)
 Frame = -1

Query: 242 DVNAVRKLLIEGRSVNEHTEEGESLLCLACSAGYYELAQVLLAM---------HANVEDR 292
           +V  +  LL  G  VN     G +    AC  G     + LL             NV D 
Sbjct: 460 NVPIINTLLSHGADVNIRDNTGCTPFANACCLGNLAAVKALLTPGESPSWSKPMINVRDN 281

Query: 293 GIKGDITPLMAAANGGHVKIVKLLLAHKADVNAQSSTGNTALTYACAGGYVDVVKVLLES 352
                 TPL  A+  GH  IV+LL+ HKAD+ A++ +G+  L+ A    + +VV VL ++
Sbjct: 280 SQN---TPLHLASQEGHTAIVELLVEHKADLAAKNDSGHNPLSLARQYKHENVVAVLQQA 110

 Score = 36.6 bits (83), Expect = 0.12,   Method: Compositional matrix adjust.
 Identities = 32/115 (27%), Positives = 48/115 (41%), Gaps = 10/115 (8%)
 Frame = -1

Query: 511 MVALLLGQGANINXXXXXXXXXXXXXXCCGGFLEVADFLIKAGADIELGC---------- 560
           ++  LL  GA++N              CC G L     L+  G                 
Sbjct: 451 IINTLLSHGADVNIRDNTGCTPFANA-CCLGNLAAVKALLTPGESPSWSKPMINVRDNSQ 275

Query: 561 STPLMEAAQEGHLELVKYLLAAGANVHATTATGDTALTYACENGHTDVADVLLQA 615
           +TPL  A+QEGH  +V+ L+   A++ A   +G   L+ A +  H +V  VL QA
Sbjct: 274 NTPLHLASQEGHTAIVELLVEHKADLAAKNDSGHNPLSLARQYKHENVVAVLQQA 110

 Score = 35.4 bits (80), Expect = 0.33,   Method: Compositional matrix adjust.
 Identities = 27/87 (31%), Positives = 42/87 (48%), Gaps = 7/87 (8%)
 Frame = -1

Query: 443 VEVARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALLIERGAS------LEEVNDEG 496
           V +   LL  GA VN+  ++  +P   A C G++     L+  G S      +  V D  
Sbjct: 457 VPIINTLLSHGADVNIRDNTGCTPFANACCLGNLAAVKALLTPGESPSWSKPMINVRDNS 278

Query: 497 Y-TPLMEAAREGHEEMVALLLGQGANI 522
             TPL  A++EGH  +V LL+   A++
Sbjct: 277 QNTPLHLASQEGHTAIVELLVEHKADL 197
>34789
          Length = 1249

 Score = 58.2 bits (139), Expect = 4e-08,   Method: Composition-based stats.
 Identities = 52/167 (31%), Positives = 79/167 (47%)
 Frame = +3

Query: 323 VNAQSSTGNTALTYACAGGYVDVVKVLLESGASIEDHNENGHTPLMEAGSAGHVEVARLL 382
           +N   S G+TAL  A   G V++V  LL++GA+    +++G+  L  A  +  V + +  
Sbjct: 57  LNQMGSDGSTALFMAVYDGNVELVDYLLKNGANPHFSSQHGNF-LHAAVLSQSVPLIQRA 233

Query: 383 LENGAGINTHSNEFKESALTLACYKGHLEMVRFLLEAGADQEHKTDEMHTALMEACMDGH 442
           L+ G  IN H N F  S LTL       E  R L+E GAD   +     T L+ +   G 
Sbjct: 234 LDLGCDINEH-NMFGNSPLTLVSRLDLPEACRMLVEHGADLNSRDRYRETPLLASVYFGC 410

Query: 443 VEVARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALLIERGASL 489
              ARLL+  GA +++  D+  S +  +          LL+  GAS 
Sbjct: 411 ELNARLLIQHGASLDLVDDNHTSAIYWSIFNNRQRTLMLLLLAGASF 551

 Score = 53.5 bits (127), Expect = 1e-06,   Method: Composition-based stats.
 Identities = 39/125 (31%), Positives = 63/125 (50%)
 Frame = +3

Query: 399 SALTLACYKGHLEMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNM 458
           +AL +A Y G++E+V +LL+ GA+  H + +    L  A +   V + +  LD G  +N 
Sbjct: 84  TALFMAVYDGNVELVDYLLKNGAN-PHFSSQHGNFLHAAVLSQSVPLIQRALDLGCDINE 260

Query: 459 PADSFESPLTLAACGGHVELAALLIERGASLEEVNDEGYTPLMEAAREGHEEMVALLLGQ 518
                 SPLTL +     E   +L+E GA L   +    TPL+ +   G E    LL+  
Sbjct: 261 HNMFGNSPLTLVSRLDLPEACRMLVEHGADLNSRDRYRETPLLASVYFGCELNARLLIQH 440

Query: 519 GANIN 523
           GA+++
Sbjct: 441 GASLD 455

 Score = 50.8 bits (120), Expect = 7e-06,   Method: Composition-based stats.
 Identities = 44/166 (26%), Positives = 75/166 (45%)
 Frame = +3

Query: 256 VNEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGIKGDITPLMAAANGGHVKIVKL 315
           +N+   +G + L +A   G  EL   LL   AN       G+   L AA     V +++ 
Sbjct: 57  LNQMGSDGSTALFMAVYDGNVELVDYLLKNGANPHFSSQHGNF--LHAAVLSQSVPLIQR 230

Query: 316 LLAHKADVNAQSSTGNTALTYACAGGYVDVVKVLLESGASIEDHNENGHTPLMEAGSAGH 375
            L    D+N  +  GN+ LT        +  ++L+E GA +   +    TPL+ +   G 
Sbjct: 231 ALDLGCDINEHNMFGNSPLTLVSRLDLPEACRMLVEHGADLNSRDRYRETPLLASVYFGC 410

Query: 376 VEVARLLLENGAGINTHSNEFKESALTLACYKGHLEMVRFLLEAGA 421
              ARLL+++GA ++   ++   SA+  + +      +  LL AGA
Sbjct: 411 ELNARLLIQHGASLDL-VDDNHTSAIYWSIFNNRQRTLMLLLLAGA 545

 Score = 50.8 bits (120), Expect = 8e-06,   Method: Composition-based stats.
 Identities = 43/140 (30%), Positives = 65/140 (46%)
 Frame = +3

Query: 545 VADFLIKAGADIELGCSTPLMEAAQEGHLELVKYLLAAGANVHATTATGDTALTYACENG 604
           VA FL + G+D     ST L  A  +G++ELV YLL  GAN H ++  G+  L  A  + 
Sbjct: 45  VAHFLNQMGSD----GSTALFMAVYDGNVELVDYLLKNGANPHFSSQHGNF-LHAAVLSQ 209

Query: 605 HTDVADVLLQAGADLEHESEGGRTPLMKAARAGHVCTVQFLISKGANVNRTTANNDHTVL 664
              +    L  G D+   +  G +PL   +R       + L+  GA++N      +  +L
Sbjct: 210 SVPLIQRALDLGCDINEHNMFGNSPLTLVSRLDLPEACRMLVEHGADLNSRDRYRETPLL 389

Query: 665 SLACAGGHLAVVELLLAHGA 684
           +    G  L    LL+ HGA
Sbjct: 390 ASVYFGCELN-ARLLIQHGA 446

 Score = 46.6 bits (109), Expect = 1e-04,   Method: Composition-based stats.
 Identities = 56/249 (22%), Positives = 106/249 (42%)
 Frame = +3

Query: 1074 QTESNHDTALTLACAGGHEELVQTLLERGASIEHRDKKGFTPLILAATAGHVGVVEILLD 1133
            Q  S+  TAL +A   G+ ELV  LL+ GA+     + G   L  A  +  V +++  LD
Sbjct: 63   QMGSDGSTALFMAVYDGNVELVDYLLKNGANPHFSSQHG-NFLHAAVLSQSVPLIQRALD 239

Query: 1134 NGADIEAQSERTKDTPLSLACSGGRQEVVELLLARGANKEHRNVSDYTPLSLAASGGYVN 1193
             G DI  +     ++PL+L       E   +L+  GA+   R+    TPL  +   G   
Sbjct: 240  LGCDIN-EHNMFGNSPLTLVSRLDLPEACRMLVEHGADLNSRDRYRETPLLASVYFGCEL 416

Query: 1194 IIKILLNAGAEINSRTGSKLGISPLMLAAMNGHTAAVKLLLDMGSDINAQIETNRNTALT 1253
              ++L+  GA ++    +    S +  +  N     + LLL  G+    Q+       + 
Sbjct: 417  NARLLIQHGASLDLVDDNH--TSAIYWSIFNNRQRTLMLLLLAGASFTPQVFRQYPRNIR 590

Query: 1254 LACFQGRTEVVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADVNAPPVP 1313
            +   +G  + +   + +  +++  A   +   M     G  + GR +++   D+N  P+P
Sbjct: 591  VMNNKGLFQFIQYYVHQPRSLQDLATACIRTHM-----GQVKQGRSIIN---DINQLPIP 746

Query: 1314 SSRDTALTI 1322
            +   + L +
Sbjct: 747  ARLKSILRL 773

 Score = 39.3 bits (90), Expect = 0.022,   Method: Composition-based stats.
 Identities = 34/123 (27%), Positives = 53/123 (43%)
 Frame = +3

Query: 1281 GLTPLMEAASGGYAEVGRVLLDKGADVNAPPVPSSRDTALTIAADKGHYKFCELLIGKGA 1340
            G T L  A   G  E+   LL  GA+   P   S     L  A         +  +  G 
Sbjct: 78   GSTALFMAVYDGNVELVDYLLKNGAN---PHFSSQHGNFLHAAVLSQSVPLIQRALDLGC 248

Query: 1341 HIDVRNKKGNTPLWLAANGGHLDVVQLLVQATADVDAADNRKITPLMAAFRKGHVKVVRY 1400
             I+  N  GN+PL L +     +  ++LV+  AD+++ D  + TPL+A+   G     R 
Sbjct: 249  DINEHNMFGNSPLTLVSRLDLPEACRMLVEHGADLNSRDRYRETPLLASVYFGCELNARL 428

Query: 1401 LVK 1403
            L++
Sbjct: 429  LIQ 437
>20792
          Length = 441

 Score = 57.0 bits (136), Expect = 1e-07,   Method: Composition-based stats.
 Identities = 34/92 (36%), Positives = 48/92 (52%)
 Frame = +2

Query: 618 DLEHESEGGRTPLMKAARAGHVCTVQFLISKGANVNRTTANNDHTVLSLACAGGHLAVVE 677
           DL+  +  G+ PL + A+ G +  + FL+ +G  V+      D T L LAC    L V+ 
Sbjct: 53  DLQIGNFEGKKPLHETAQFGQLDCMNFLLQRGVQVD-CLKRADWTPLMLACTKCQLPVIS 229

Query: 678 LLLAHGADPTHRLKDGSTMLIEAAKGGHTSVV 709
           LLL HGADP    KDG      AA+ GH  ++
Sbjct: 230 LLLKHGADPALVNKDGWNSFHIAAREGHVDIL 325

 Score = 44.7 bits (104), Expect = 5e-04,   Method: Composition-based stats.
 Identities = 30/88 (34%), Positives = 40/88 (45%), Gaps = 3/88 (3%)
 Frame = +2

Query: 555 DIELG---CSTPLMEAAQEGHLELVKYLLAAGANVHATTATGDTALTYACENGHTDVADV 611
           D+++G      PL E AQ G L+ + +LL  G  V        T L  AC      V  +
Sbjct: 53  DLQIGNFEGKKPLHETAQFGQLDCMNFLLQRGVQVDCLKRADWTPLMLACTKCQLPVISL 232

Query: 612 LLQAGADLEHESEGGRTPLMKAARAGHV 639
           LL+ GAD    ++ G      AAR GHV
Sbjct: 233 LLKHGADPALVNKDGWNSFHIAAREGHV 316

 Score = 44.3 bits (103), Expect = 6e-04,   Method: Composition-based stats.
 Identities = 28/86 (32%), Positives = 43/86 (50%)
 Frame = +2

Query: 1111 KGFTPLILAATAGHVGVVEILLDNGADIEAQSERTKDTPLSLACSGGRQEVVELLLARGA 1170
            +G  PL   A  G +  +  LL  G  ++   +R   TPL LAC+  +  V+ LLL  GA
Sbjct: 74   EGKKPLHETAQFGQLDCMNFLLQRGVQVDCL-KRADWTPLMLACTKCQLPVISLLLKHGA 250

Query: 1171 NKEHRNVSDYTPLSLAASGGYVNIIK 1196
            +    N   +    +AA  G+V+I+K
Sbjct: 251  DPALVNKDGWNSFHIAAREGHVDILK 328

 Score = 43.5 bits (101), Expect = 0.001,   Method: Composition-based stats.
 Identities = 26/84 (30%), Positives = 41/84 (48%)
 Frame = +2

Query: 429 EMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALLIERGAS 488
           E    L E    G ++    LL  G QV+    +  +PL LA     + + +LL++ GA 
Sbjct: 74  EGKKPLHETAQFGQLDCMNFLLQRGVQVDCLKRADWTPLMLACTKCQLPVISLLLKHGAD 253

Query: 489 LEEVNDEGYTPLMEAAREGHEEMV 512
              VN +G+     AAREGH +++
Sbjct: 254 PALVNKDGWNSFHIAAREGHVDIL 325

 Score = 35.4 bits (80), Expect(2) = 0.006,   Method: Composition-based stats.
 Identities = 18/53 (33%), Positives = 27/53 (50%)
 Frame = +2

Query: 295 KGDITPLMAAANGGHVKIVKLLLAHKADVNAQSSTGNTALTYACAGGYVDVVK 347
           + D TPLM A     + ++ LLL H AD    +  G  +   A   G+VD++K
Sbjct: 170 RADWTPLMLACTKCQLPVISLLLKHGADPALVNKDGWNSFHIAAREGHVDILK 328

 Score = 24.6 bits (52), Expect(2) = 0.006,   Method: Compositional matrix adjust.
 Identities = 14/38 (36%), Positives = 20/38 (52%)
 Frame = +3

Query: 380 RLLLENGAGINTHSNEFKESALTLACYKGHLEMVRFLL 417
           + LL + AG+   S+    + L  A   GH E VRF+L
Sbjct: 327 KTLLASNAGVWNVSSHNSRTPLHTAALHGHSEAVRFML 440

 Score = 38.9 bits (89), Expect = 0.030,   Method: Composition-based stats.
 Identities = 24/88 (27%), Positives = 39/88 (44%)
 Frame = +2

Query: 360 NENGHTPLMEAGSAGHVEVARLLLENGAGINTHSNEFKESALTLACYKGHLEMVRFLLEA 419
           N  G  PL E    G ++    LL+ G  ++        + L LAC K  L ++  LL+ 
Sbjct: 68  NFEGKKPLHETAQFGQLDCMNFLLQRGVQVDCLKRA-DWTPLMLACTKCQLPVISLLLKH 244

Query: 420 GADQEHKTDEMHTALMEACMDGHVEVAR 447
           GAD      +   +   A  +GHV++ +
Sbjct: 245 GADPALVNKDGWNSFHIAAREGHVDILK 328

 Score = 37.0 bits (84), Expect = 0.12,   Method: Composition-based stats.
 Identities = 17/48 (35%), Positives = 29/48 (60%)
 Frame = +2

Query: 1090 GHEELVQTLLERGASIEHRDKKGFTPLILAATAGHVGVVEILLDNGAD 1137
            G  + +  LL+RG  ++   +  +TPL+LA T   + V+ +LL +GAD
Sbjct: 110  GQLDCMNFLLQRGVQVDCLKRADWTPLMLACTKCQLPVISLLLKHGAD 253

 Score = 36.2 bits (82), Expect = 0.18,   Method: Composition-based stats.
 Identities = 28/100 (28%), Positives = 42/100 (42%)
 Frame = +2

Query: 300 PLMAAANGGHVKIVKLLLAHKADVNAQSSTGNTALTYACAGGYVDVVKVLLESGASIEDH 359
           PL   A  G +  +  LL     V+       T L  AC    + V+ +LL+ GA     
Sbjct: 86  PLHETAQFGQLDCMNFLLQRGVQVDCLKRADWTPLMLACTKCQLPVISLLLKHGADPALV 265

Query: 360 NENGHTPLMEAGSAGHVEVARLLLENGAGINTHSNEFKES 399
           N++G      A   GHV++    L+N  G+   S E  +S
Sbjct: 266 NKDGWNSFHIAAREGHVDI----LKNTTGLECWSLECFQS 373

 Score = 31.6 bits (70), Expect(2) = 0.51,   Method: Composition-based stats.
 Identities = 22/71 (30%), Positives = 32/71 (45%)
 Frame = +2

Query: 408 GHLEMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPL 467
           G L+ + FLL+ G   +       T LM AC    + V  LLL  GA   +      +  
Sbjct: 110 GQLDCMNFLLQRGVQVDCLKRADWTPLMLACTKCQLPVISLLLKHGADPALVNKDGWNSF 289

Query: 468 TLAACGGHVEL 478
            +AA  GHV++
Sbjct: 290 HIAAREGHVDI 322

 Score = 21.9 bits (45), Expect(2) = 0.51,   Method: Compositional matrix adjust.
 Identities = 10/19 (52%), Positives = 11/19 (57%)
 Frame = +3

Query: 498 TPLMEAAREGHEEMVALLL 516
           TPL  AA  GH E V  +L
Sbjct: 384 TPLHTAALHGHSEAVRFML 440

 Score = 34.3 bits (77), Expect = 0.67,   Method: Composition-based stats.
 Identities = 20/69 (28%), Positives = 37/69 (53%), Gaps = 2/69 (2%)
 Frame = +2

Query: 455 QVNMPADSFE--SPLTLAACGGHVELAALLIERGASLEEVNDEGYTPLMEAAREGHEEMV 512
           +V++   +FE   PL   A  G ++    L++RG  ++ +    +TPLM A  +    ++
Sbjct: 47  EVDLQIGNFEGKKPLHETAQFGQLDCMNFLLQRGVQVDCLKRADWTPLMLACTKCQLPVI 226

Query: 513 ALLLGQGAN 521
           +LLL  GA+
Sbjct: 227 SLLLKHGAD 253

 Score = 33.1 bits (74), Expect = 1.5,   Method: Composition-based stats.
 Identities = 26/93 (27%), Positives = 42/93 (45%)
 Frame = +2

Query: 1204 EINSRTGSKLGISPLMLAAMNGHTAAVKLLLDMGSDINAQIETNRNTALTLACFQGRTEV 1263
            E++ + G+  G  PL   A  G    +  LL  G  ++  ++    T L LAC + +  V
Sbjct: 47   EVDLQIGNFEGKKPLHETAQFGQLDCMNFLLQRGVQVDC-LKRADWTPLMLACTKCQLPV 223

Query: 1264 VSLLLDRKANVEHRAKTGLTPLMEAASGGYAEV 1296
            +SLLL   A+     K G      AA  G+ ++
Sbjct: 224  ISLLLKHGADPALVNKDGWNSFHIAAREGHVDI 322

 Score = 32.0 bits (71), Expect = 3.3,   Method: Composition-based stats.
 Identities = 24/98 (24%), Positives = 46/98 (46%)
 Frame = +2

Query: 317 LAHKADVNAQSSTGNTALTYACAGGYVDVVKVLLESGASIEDHNENGHTPLMEAGSAGHV 376
           L  + D+   +  G   L      G +D +  LL+ G  ++       TPLM A +   +
Sbjct: 38  LCDEVDLQIGNFEGKKPLHETAQFGQLDCMNFLLQRGVQVDCLKRADWTPLMLACTKCQL 217

Query: 377 EVARLLLENGAGINTHSNEFKESALTLACYKGHLEMVR 414
            V  LLL++GA      N+   ++  +A  +GH+++++
Sbjct: 218 PVISLLLKHGAD-PALVNKDGWNSFHIAAREGHVDILK 328
>16561
          Length = 2029

 Score = 33.5 bits (75), Expect(3) = 6e-07,   Method: Compositional matrix adjust.
 Identities = 15/37 (40%), Positives = 24/37 (64%)
 Frame = -3

Query: 1366 QLLVQATADVDAADNRKITPLMAAFRKGHVKVVRYLV 1402
            Q L++  A+VD  +NR+ TPL+ A  +GH  ++  LV
Sbjct: 1559 QHLLRNRAEVDIRNNRQQTPLLLAVSQGHSSLIELLV 1449

 Score = 32.3 bits (72), Expect(3) = 6e-07,   Method: Composition-based stats.
 Identities = 25/78 (32%), Positives = 38/78 (48%)
 Frame = -3

Query: 1249 NTALTLACFQGRTEVVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADVN 1308
            +TAL  + F  + +V+ LLL + A +      G + L  A +  + +   VLL+ G DVN
Sbjct: 2009 DTALHYSAFGNQPDVLQLLLSKGAKINALNNGGCSTLHVAVNKQHIKCVHVLLNXGCDVN 1830

Query: 1309 APPVPSSRDTALTIAADK 1326
                 +  DTAL  A  K
Sbjct: 1829 XQ--DAYGDTALHDAIGK 1782

 Score = 26.6 bits (57), Expect(3) = 6e-07,   Method: Composition-based stats.
 Identities = 19/52 (36%), Positives = 28/52 (53%), Gaps = 1/52 (1%)
 Frame = -2

Query: 1323 AADKGHYKFCELLIGKGAHI-DVRNKKGNTPLWLAANGGHLDVVQLLVQATA 1373
            AA KG+    E ++ K   I D+R   G + L LAA  GH DV   L++ ++
Sbjct: 1692 AALKGNVFATERVLHKCRQIVDLRKDDGFSALHLAALNGHKDVAAALIEESS 1537

 Score = 49.7 bits (117), Expect = 2e-05,   Method: Composition-based stats.
 Identities = 71/277 (25%), Positives = 113/277 (40%), Gaps = 38/277 (13%)
 Frame = -3

Query: 262  EGESLLCLACSAGYYELAQVLLAMHANVEDRGIKGDITPLMAAANGGHVKIVKLLLAHKA 321
            +G++ L  +      ++ Q+LL+  A +      G  + L  A N  H+K V +LL    
Sbjct: 2015 DGDTALHYSAFGNQPDVLQLLLSKGAKINALN-NGGCSTLHVAVNKQHIKCVHVLLNXGC 1839

Query: 322  DVNAQSSTGNTALTYACAGGYVDVVKVLLESGASIEDHNEN--GHTPLME-------AGS 372
            DVN Q + G+TAL  A     V  +  L  + A I     +    + +M+         S
Sbjct: 1838 DVNXQDAYGDTALHDAIGKRAVKSLTSLSITLALISPSETSVASMSSIMQP*RAMCLPRS 1659

Query: 373  AGHVEVARL--------------------------LLENGAGINTHSNEFKESALTLACY 406
            A    V RL                          LL N A ++  +N  +++ L LA  
Sbjct: 1658 ASCTNVDRLWT*GKMMGFLHFTWLL*MDTRMLQQHLLRNRAEVDIRNNR-QQTPLLLAVS 1482

Query: 407  KGHLEMVRFLLEAGADQEHKTDEMHTALMEACMDGHV---EVARLLLDSGAQVNMPADSF 463
            +GH  ++  L+ A AD     ++  T L  A M   V   + +R+L    +Q+ M  D  
Sbjct: 1481 QGHSSLIELLVHAQADINVSDEDGDTCLHLALMRQTVATEDSSRMLDSIRSQLGMGEDEA 1302

Query: 464  ESPLTLAACGGHVELAALLIERGASLEEVNDEGYTPL 500
            +   T AA      +A  L ++GASL   N +G  PL
Sbjct: 1301 Q---TGAA------IACYLAQQGASLTACNQQGKXPL 1218

 Score = 48.1 bits (113), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 23/61 (37%), Positives = 35/61 (57%)
 Frame = -3

Query: 1335 LIGKGAHIDVRNKKGNTPLWLAANGGHLDVVQLLVQATADVDAADNRKITPLMAAFRKGH 1394
            L+   A +D+RN +  TPL LA + GH  +++LLV A AD++ +D    T L  A  +  
Sbjct: 1553 LLRNRAEVDIRNNRQQTPLLLAVSQGHSSLIELLVHAQADINVSDEDGDTCLHLALMRQT 1374

Query: 1395 V 1395
            V
Sbjct: 1373 V 1371

 Score = 41.2 bits (95), Expect = 0.006,   Method: Composition-based stats.
 Identities = 29/85 (34%), Positives = 40/85 (47%)
 Frame = -3

Query: 1317 DTALTIAADKGHYKFCELLIGKGAHIDVRNKKGNTPLWLAANGGHLDVVQLLVQATADVD 1376
            DTAL  +A        +LL+ KGA I+  N  G + L +A N  H+  V +L+    DV+
Sbjct: 2009 DTALHYSAFGNQPDVLQLLLSKGAKINALNNGGCSTLHVAVNKQHIKCVHVLLNXGCDVN 1830

Query: 1377 AADNRKITPLMAAFRKGHVKVVRYL 1401
              D    T L  A  K  VK +  L
Sbjct: 1829 XQDAYGDTALHDAIGKRAVKSLTSL 1755

 Score = 40.8 bits (94), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 24/60 (40%), Positives = 35/60 (58%)
 Frame = -3

Query: 1094 LVQTLLERGASIEHRDKKGFTPLILAATAGHVGVVEILLDNGADIEAQSERTKDTPLSLA 1153
            L Q LL   A ++ R+ +  TPL+LA + GH  ++E+L+   ADI   S+   DT L LA
Sbjct: 1565 LQQHLLRNRAEVDIRNNRQQTPLLLAVSQGHSSLIELLVHAQADINV-SDEDGDTCLHLA 1389

 Score = 39.3 bits (90), Expect = 0.024,   Method: Composition-based stats.
 Identities = 50/218 (22%), Positives = 94/218 (43%), Gaps = 13/218 (5%)
 Frame = -3

Query: 296  GDI----TPLMAAANGGHVKIVKLLLAHKADVNAQSSTGNTALTYACAGGYVDVVKVLLE 351
            GDI    T L  +A G    +++LLL+  A +NA ++ G + L  A    ++  V VLL 
Sbjct: 2027 GDIRDGDTALHYSAFGNQPDVLQLLLSKGAKINALNNGGCSTLHVAVNKQHIKCVHVLLN 1848

Query: 352  SGASIEDHNENGHTPLMEAGSAGHVEVARLLLENGAGINTHSNEFKESALTLACYKGHLE 411
             G  +   +  G T L +A       + +  +++   ++        S  ++A     ++
Sbjct: 1847 XGCDVNXQDAYGDTALHDA-------IGKRAVKSLTSLSITLALISPSETSVASMSSIMQ 1689

Query: 412  MVRFLLEAGADQEHKTDEMHT--ALMEAC-------MDGHVEVARLLLDSGAQVNMPADS 462
              R +    +      D + T   +M          MD  + + + LL + A+V++  + 
Sbjct: 1688 P*RAMCLPRSASCTNVDRLWT*GKMMGFLHFTWLL*MDTRM-LQQHLLRNRAEVDIRNNR 1512

Query: 463  FESPLTLAACGGHVELAALLIERGASLEEVNDEGYTPL 500
             ++PL LA   GH  L  LL+   A +   +++G T L
Sbjct: 1511 QQTPLLLAVSQGHSSLIELLVHAQADINVSDEDGDTCL 1398

 Score = 38.5 bits (88), Expect = 0.039,   Method: Composition-based stats.
 Identities = 19/65 (29%), Positives = 36/65 (55%)
 Frame = -3

Query: 1144 RTKDTPLSLACSGGRQEVVELLLARGANKEHRNVSDYTPLSLAASGGYVNIIKILLNAGA 1203
            R  DT L  +  G + +V++LLL++GA     N    + L +A +  ++  + +LLN G 
Sbjct: 2018 RDGDTALHYSAFGNQPDVLQLLLSKGAKINALNNGGCSTLHVAVNKQHIKCVHVLLNXGC 1839

Query: 1204 EINSR 1208
            ++N +
Sbjct: 1838 DVNXQ 1824

 Score = 37.4 bits (85), Expect = 0.073,   Method: Composition-based stats.
 Identities = 22/60 (36%), Positives = 34/60 (56%)
 Frame = -3

Query: 1343 DVRNKKGNTPLWLAANGGHLDVVQLLVQATADVDAADNRKITPLMAAFRKGHVKVVRYLV 1402
            D+R+  G+T L  +A G   DV+QLL+   A ++A +N   + L  A  K H+K V  L+
Sbjct: 2024 DIRD--GDTALHYSAFGNQPDVLQLLLSKGAKINALNNGGCSTLHVAVNKQHIKCVHVLL 1851

 Score = 36.2 bits (82), Expect = 0.18,   Method: Composition-based stats.
 Identities = 23/75 (30%), Positives = 41/75 (54%)
 Frame = -3

Query: 1279 KTGLTPLMEAASGGYAEVGRVLLDKGADVNAPPVPSSRDTALTIAADKGHYKFCELLIGK 1338
            + G T L  +A G   +V ++LL KGA +NA  + +   + L +A +K H K   +L+  
Sbjct: 2018 RDGDTALHYSAFGNQPDVLQLLLSKGAKINA--LNNGGCSTLHVAVNKQHIKCVHVLLNX 1845

Query: 1339 GAHIDVRNKKGNTPL 1353
            G  ++ ++  G+T L
Sbjct: 1844 GCDVNXQDAYGDTAL 1800

 Score = 32.7 bits (73), Expect = 2.1,   Method: Compositional matrix adjust.
 Identities = 21/58 (36%), Positives = 34/58 (58%)
 Frame = -3

Query: 1198 LLNAGAEINSRTGSKLGISPLMLAAMNGHTAAVKLLLDMGSDINAQIETNRNTALTLA 1255
            LL   AE++ R   +   +PL+LA   GH++ ++LL+   +DIN   E + +T L LA
Sbjct: 1553 LLRNRAEVDIRNNRQQ--TPLLLAVSQGHSSLIELLVHAQADINVSDE-DGDTCLHLA 1389

 Score = 32.7 bits (73), Expect = 2.1,   Method: Compositional matrix adjust.
 Identities = 15/39 (38%), Positives = 24/39 (61%)
 Frame = -3

Query: 562  TPLMEAAQEGHLELVKYLLAAGANVHATTATGDTALTYA 600
            TPL+ A  +GH  L++ L+ A A+++ +   GDT L  A
Sbjct: 1505 TPLLLAVSQGHSSLIELLVHAQADINVSDEDGDTCLHLA 1389

 Score = 31.6 bits (70), Expect = 4.1,   Method: Compositional matrix adjust.
 Identities = 16/41 (39%), Positives = 24/41 (58%)
 Frame = -3

Query: 1316 RDTALTIAADKGHYKFCELLIGKGAHIDVRNKKGNTPLWLA 1356
            + T L +A  +GH    ELL+   A I+V ++ G+T L LA
Sbjct: 1511 QQTPLLLAVSQGHSSLIELLVHAQADINVSDEDGDTCLHLA 1389
>38834
          Length = 496

 Score = 53.5 bits (127), Expect = 1e-06,   Method: Composition-based stats.
 Identities = 29/93 (31%), Positives = 50/93 (53%)
 Frame = -1

Query: 1152 LACSGGRQEVVELLLARGANKEHRNVSDYTPLSLAASGGYVNIIKILLNAGAEINSRTGS 1211
            +ACS G  ++ E+L  RG      N++ YTP  L+      +I   L+   AEIN  T +
Sbjct: 496  IACSSGHLDIAEMLHRRGVQINVVNINGYTPXHLSVYFNKFDITHFLVKINAEIN--TVN 323

Query: 1212 KLGISPLMLAAMNGHTAAVKLLLDMGSDINAQI 1244
              G +P+ LAA+ G++  + L+++ G  +N  +
Sbjct: 322  NAGQTPVYLAALRGNSKILALMVNAGCKVNGLV 224

 Score = 52.0 bits (123), Expect = 3e-06,   Method: Composition-based stats.
 Identities = 25/87 (28%), Positives = 48/87 (55%)
 Frame = -1

Query: 437 ACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALLIERGASLEEVNDEG 496
           AC  GH+++A +L   G Q+N+   +  +P  L+      ++   L++  A +  VN+ G
Sbjct: 493 ACSSGHLDIAEMLHRRGVQINVVNINGYTPXHLSVYFNKFDITHFLVKINAEINTVNNAG 314

Query: 497 YTPLMEAAREGHEEMVALLLGQGANIN 523
            TP+  AA  G+ +++AL++  G  +N
Sbjct: 313 QTPVYLAALRGNSKILALMVNAGCKVN 233

 Score = 40.8 bits (94), Expect = 0.007,   Method: Composition-based stats.
 Identities = 23/84 (27%), Positives = 46/84 (54%)
 Frame = -1

Query: 337 ACAGGYVDVVKVLLESGASIEDHNENGHTPLMEAGSAGHVEVARLLLENGAGINTHSNEF 396
           AC+ G++D+ ++L   G  I   N NG+TP   +      ++   L++  A INT +N  
Sbjct: 493 ACSSGHLDIAEMLHRRGVQINVVNINGYTPXHLSVYFNKFDITHFLVKINAEINTVNNA- 317

Query: 397 KESALTLACYKGHLEMVRFLLEAG 420
            ++ + LA  +G+ +++  ++ AG
Sbjct: 316 GQTPVYLAALRGNSKILALMVNAG 245

 Score = 40.4 bits (93), Expect = 0.011,   Method: Composition-based stats.
 Identities = 27/116 (23%), Positives = 54/116 (46%)
 Frame = -1

Query: 1288 AASGGYAEVGRVLLDKGADVNAPPVPSSRDTALTIAADKGHYKFCELLIGKGAHIDVRNK 1347
            A S G+ ++  +L  +G  +N   +       L++  +K  +     L+   A I+  N 
Sbjct: 493  ACSSGHLDIAEMLHRRGVQINVVNINGYTPXHLSVYFNK--FDITHFLVKINAEINTVNN 320

Query: 1348 KGNTPLWLAANGGHLDVVQLLVQATADVDAADNRKITPLMAAFRKGHVKVVRYLVK 1403
             G TP++LAA  G+  ++ L+V A   V    N  ++ +     K  ++ ++YL +
Sbjct: 319  AGQTPVYLAALRGNSKILALMVNAGCKV----NGLVSDISTRINKDLLEYIQYLAR 164

 Score = 37.7 bits (86), Expect = 0.066,   Method: Composition-based stats.
 Identities = 22/85 (25%), Positives = 41/85 (48%)
 Frame = -1

Query: 1085 LACAGGHEELVQTLLERGASIEHRDKKGFTPLILAATAGHVGVVEILLDNGADIEAQSER 1144
            +AC+ GH ++ + L  RG  I   +  G+TP  L+       +   L+   A+I   +  
Sbjct: 496  IACSSGHLDIAEMLHRRGVQINVVNINGYTPXHLSVYFNKFDITHFLVKINAEINTVNNA 317

Query: 1145 TKDTPLSLACSGGRQEVVELLLARG 1169
             + TP+ LA   G  +++ L++  G
Sbjct: 316  GQ-TPVYLAALRGNSKILALMVNAG 245

 Score = 37.7 bits (86), Expect = 0.066,   Method: Composition-based stats.
 Identities = 24/89 (26%), Positives = 44/89 (49%)
 Frame = -1

Query: 1118 LAATAGHVGVVEILLDNGADIEAQSERTKDTPLSLACSGGRQEVVELLLARGANKEHRNV 1177
            +A ++GH+ + E+L   G  I   +     TP  L+    + ++   L+   A     N 
Sbjct: 496  IACSSGHLDIAEMLHRRGVQINVVNINGY-TPXHLSVYFNKFDITHFLVKINAEINTVNN 320

Query: 1178 SDYTPLSLAASGGYVNIIKILLNAGAEIN 1206
            +  TP+ LAA  G   I+ +++NAG ++N
Sbjct: 319  AGQTPVYLAALRGNSKILALMVNAGCKVN 233

 Score = 37.4 bits (85), Expect = 0.073,   Method: Composition-based stats.
 Identities = 26/98 (26%), Positives = 44/98 (44%)
 Frame = -1

Query: 600 ACENGHTDVADVLLQAGADLEHESEGGRTPLMKAARAGHVCTVQFLISKGANVNRTTANN 659
           AC +GH D+A++L + G  +   +  G TP   +          FL+   A +N T  N 
Sbjct: 493 ACSSGHLDIAEMLHRRGVQINVVNINGYTPXHLSVYFNKFDITHFLVKINAEIN-TVNNA 317

Query: 660 DHTVLSLACAGGHLAVVELLLAHGADPTHRLKDGSTML 697
             T + LA   G+  ++ L++  G      + D ST +
Sbjct: 316 GQTPVYLAALRGNSKILALMVNAGCKVNGLVSDISTRI 203

 Score = 32.7 bits (73), Expect = 1.9,   Method: Composition-based stats.
 Identities = 17/55 (30%), Positives = 27/55 (49%)
 Frame = -1

Query: 469 LAACGGHVELAALLIERGASLEEVNDEGYTPLMEAAREGHEEMVALLLGQGANIN 523
           +A   GH+++A +L  RG  +  VN  GYTP   +      ++   L+   A IN
Sbjct: 496 IACSSGHLDIAEMLHRRGVQINVVNINGYTPXHLSVYFNKFDITHFLVKINAEIN 332
>20884
          Length = 712

 Score = 37.0 bits (84), Expect(2) = 1e-06,   Method: Compositional matrix adjust.
 Identities = 20/52 (38%), Positives = 29/52 (55%)
 Frame = +1

Query: 562 TPLMEAAQEGHLELVKYLLAAGANVHATTATGDTALTYACENGHTDVADVLL 613
           TPL  A     + +V+ L+ AGA + A    G+TAL  AC  G T++  +LL
Sbjct: 304 TPLHLAVATRQMWVVRRLMVAGAAMEAPDYCGNTALHIACREGMTEMVKLLL 459

 Score = 35.8 bits (81), Expect(2) = 1e-06,   Method: Composition-based stats.
 Identities = 20/62 (32%), Positives = 32/62 (51%)
 Frame = +2

Query: 618 DLEHESEGGRTPLMKAARAGHVCTVQFLISKGANVNRTTANNDHTVLSLACAGGHLAVVE 677
           DL   +  G T    A + GH+  +  L+ +GAN+N     +  T+L +A   G+L  +E
Sbjct: 527 DLAIRNYEGYTCAHLALQTGHLHILPLLLERGANINEQDGKSGRTLLHMAADLGYLQALE 706

Query: 678 LL 679
           LL
Sbjct: 707 LL 712

 Score = 35.8 bits (81), Expect(2) = 2e-05,   Method: Compositional matrix adjust.
 Identities = 20/52 (38%), Positives = 28/52 (53%)
 Frame = +1

Query: 299 TPLMAAANGGHVKIVKLLLAHKADVNAQSSTGNTALTYACAGGYVDVVKVLL 350
           TPL  A     + +V+ L+   A + A    GNTAL  AC  G  ++VK+LL
Sbjct: 304 TPLHLAVATRQMWVVRRLMVAGAAMEAPDYCGNTALHIACREGMTEMVKLLL 459

 Score = 33.1 bits (74), Expect(2) = 2e-05,   Method: Composition-based stats.
 Identities = 19/57 (33%), Positives = 28/57 (49%)
 Frame = +2

Query: 360 NENGHTPLMEAGSAGHVEVARLLLENGAGINTHSNEFKESALTLACYKGHLEMVRFL 416
           N  G+T    A   GH+ +  LLLE GA IN    +   + L +A   G+L+ +  L
Sbjct: 542 NYEGYTCAHLALQTGHLHILPLLLERGANINEQDGKSGRTLLHMAADLGYLQALELL 712

 Score = 33.5 bits (75), Expect(2) = 3e-04,   Method: Compositional matrix adjust.
 Identities = 28/86 (32%), Positives = 42/86 (48%), Gaps = 1/86 (1%)
 Frame = +1

Query: 394 NEFKESALTLACYKGHLEMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSG 453
           N   ++ L LA     + +VR L+ AGA  E      +TAL  AC +G  E+ +LLL   
Sbjct: 289 NMLHQTPLHLAVATRQMWVVRRLMVAGAAMEAPDYCGNTALHIACREGMTEMVKLLLTPV 468

Query: 454 AQVNMPADSFESP-LTLAACGGHVEL 478
                 A+ +  P LT++   G+ EL
Sbjct: 469 QYQETLANQYSLPQLTISPGPGYQEL 546

 Score = 31.2 bits (69), Expect(2) = 3e-04,   Method: Composition-based stats.
 Identities = 16/31 (51%), Positives = 20/31 (64%)
 Frame = +2

Query: 493 NDEGYTPLMEAAREGHEEMVALLLGQGANIN 523
           N EGYT    A + GH  ++ LLL +GANIN
Sbjct: 542 NYEGYTCAHLALQTGHLHILPLLLERGANIN 634

 Score = 38.1 bits (87), Expect(2) = 0.003,   Method: Composition-based stats.
 Identities = 20/58 (34%), Positives = 34/58 (58%)
 Frame = +2

Query: 1108 RDKKGFTPLILAATAGHVGVVEILLDNGADIEAQSERTKDTPLSLACSGGRQEVVELL 1165
            R+ +G+T   LA   GH+ ++ +LL+ GA+I  Q  ++  T L +A   G  + +ELL
Sbjct: 539  RNYEGYTCAHLALQTGHLHILPLLLERGANINEQDGKSGRTLLHMAADLGYLQALELL 712

 Score = 22.7 bits (47), Expect(2) = 0.003,   Method: Compositional matrix adjust.
 Identities = 10/20 (50%), Positives = 14/20 (70%)
 Frame = +1

Query: 1080 DTALTLACAGGHEELVQTLL 1099
            +TAL +AC  G  E+V+ LL
Sbjct: 400  NTALHIACREGMTEMVKLLL 459

 Score = 29.6 bits (65), Expect(2) = 0.027,   Method: Composition-based stats.
 Identities = 20/52 (38%), Positives = 27/52 (51%), Gaps = 1/52 (1%)
 Frame = +2

Query: 1250 TALTLACFQGRTEVVSLLLDRKANV-EHRAKTGLTPLMEAASGGYAEVGRVL 1300
            T   LA   G   ++ LLL+R AN+ E   K+G T L  AA  GY +   +L
Sbjct: 557  TCAHLALQTGHLHILPLLLERGANINEQDGKSGRTLLHMAADLGYLQALELL 712

 Score = 28.1 bits (61), Expect(2) = 0.027,   Method: Compositional matrix adjust.
 Identities = 20/59 (33%), Positives = 31/59 (52%)
 Frame = +1

Query: 1176 NVSDYTPLSLAASGGYVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHTAAVKLLL 1234
            N+   TPL LA +   + +++ L+ AGA + +      G + L +A   G T  VKLLL
Sbjct: 289  NMLHQTPLHLAVATRQMWVVRRLMVAGAAMEA--PDYCGNTALHIACREGMTEMVKLLL 459

 Score = 38.5 bits (88), Expect = 0.039,   Method: Compositional matrix adjust.
 Identities = 37/118 (31%), Positives = 53/118 (44%), Gaps = 1/118 (0%)
 Frame = +1

Query: 1183 LSLAASGGYVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHTAAVKLLLDMGSDINA 1242
            +S+A S  Y+NI  +L                 +PL LA        V+ L+  G+ + A
Sbjct: 250  ISVAPSPDYINIPNMLHQ---------------TPLHLAVATRQMWVVRRLMVAGAAMEA 384

Query: 1243 QIETNRNTALTLACFQGRTEVVSLLLDRKANVEHRAKTGLTPLMEAASG-GYAEVGRV 1299
              +   NTAL +AC +G TE+V LLL      E  A     P +  + G GY E+ RV
Sbjct: 385  P-DYCGNTALHIACREGMTEMVKLLLTPVQYQETLANQYSLPQLTISPGPGYQEL*RV 555

 Score = 36.2 bits (82), Expect = 0.19,   Method: Composition-based stats.
 Identities = 22/52 (42%), Positives = 31/52 (59%), Gaps = 1/52 (1%)
 Frame = +2

Query: 1081 TALTLACAGGHEELVQTLLERGASIEHRD-KKGFTPLILAATAGHVGVVEIL 1131
            T   LA   GH  ++  LLERGA+I  +D K G T L +AA  G++  +E+L
Sbjct: 557  TCAHLALQTGHLHILPLLLERGANINEQDGKSGRTLLHMAADLGYLQALELL 712

 Score = 35.4 bits (80), Expect = 0.30,   Method: Compositional matrix adjust.
 Identities = 23/61 (37%), Positives = 33/61 (54%)
 Frame = +1

Query: 456 VNMPADSFESPLTLAACGGHVELAALLIERGASLEEVNDEGYTPLMEAAREGHEEMVALL 515
           +N+P    ++PL LA     + +   L+  GA++E  +  G T L  A REG  EMV LL
Sbjct: 277 INIPNMLHQTPLHLAVATRQMWVVRRLMVAGAAMEAPDYCGNTALHIACREGMTEMVKLL 456

Query: 516 L 516
           L
Sbjct: 457 L 459

 Score = 33.9 bits (76), Expect = 0.89,   Method: Compositional matrix adjust.
 Identities = 22/53 (41%), Positives = 30/53 (56%)
 Frame = +1

Query: 1114 TPLILAATAGHVGVVEILLDNGADIEAQSERTKDTPLSLACSGGRQEVVELLL 1166
            TPL LA     + VV  L+  GA +EA  +   +T L +AC  G  E+V+LLL
Sbjct: 304  TPLHLAVATRQMWVVRRLMVAGAAMEA-PDYCGNTALHIACREGMTEMVKLLL 459
>12417
          Length = 954

 Score = 51.6 bits (122), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 50/155 (32%), Positives = 66/155 (42%), Gaps = 4/155 (2%)
 Frame = +2

Query: 233 SLAEACSEGDVNAVRKLLI----EGRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHAN 288
           SL EA ++ DV+ V  L +    E RS N      + +   A  A   E A V LAM   
Sbjct: 98  SLVEAVAQNDVDHVMMLGVTNPTEYRSPN-----SDYMTKRARKAWLEERASVALAM--- 253

Query: 289 VEDRGIKGDITPLMAAANGGHVKIVKLLLAHKADVNAQSSTGNTALTYACAGGYVDVVKV 348
                          AAN G  K+   L+   ADVN+ +  G T L  A A G+  +V +
Sbjct: 254 ---------------AANRGLDKMCSQLIQTGADVNSATEHGRTPLHXASAQGHGHIVDL 388

Query: 349 LLESGASIEDHNENGHTPLMEAGSAGHVEVARLLL 383
           LLE GA I+  ++ G T L  A   G     R L 
Sbjct: 389 LLEKGADIDAEDDYGDTALSIADQFGFKSCGRXLF 493

 Score = 51.6 bits (122), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 32/84 (38%), Positives = 45/84 (53%)
 Frame = +2

Query: 1319 ALTIAADKGHYKFCELLIGKGAHIDVRNKKGNTPLWLAANGGHLDVVQLLVQATADVDAA 1378
            AL +AA++G  K C  LI  GA ++   + G TPL  A+  GH  +V LL++  AD+DA 
Sbjct: 242  ALAMAANRGLDKMCSQLIQTGADVNSATEHGRTPLHXASAQGHGHIVDLLLEKGADIDAE 421

Query: 1379 DNRKITPLMAAFRKGHVKVVRYLV 1402
            D+   T L  A + G     R L 
Sbjct: 422  DDYGDTALSIADQFGFKSCGRXLF 493

 Score = 49.7 bits (117), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 30/85 (35%), Positives = 47/85 (55%)
 Frame = +2

Query: 1073 AQTESNHDTALTLACAGGHEELVQTLLERGASIEHRDKKGFTPLILAATAGHVGVVEILL 1132
            A  E     AL +A   G +++   L++ GA +    + G TPL  A+  GH  +V++LL
Sbjct: 215  AWLEERASVALAMAANRGLDKMCSQLIQTGADVNSATEHGRTPLHXASAQGHGHIVDLLL 394

Query: 1133 DNGADIEAQSERTKDTPLSLACSGG 1157
            + GADI+A+ +   DT LS+A   G
Sbjct: 395  EKGADIDAEDD-YGDTALSIADQFG 466

 Score = 48.9 bits (115), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 32/94 (34%), Positives = 49/94 (52%), Gaps = 2/94 (2%)
 Frame = +2

Query: 546 ADFLIKAG--ADIELGCSTPLMEAAQEGHLELVKYLLAAGANVHATTATGDTALTYACEN 603
           +D++ K    A +E   S  L  AA  G  ++   L+  GA+V++ T  G T L  A   
Sbjct: 185 SDYMTKRARKAWLEERASVALAMAANRGLDKMCSQLIQTGADVNSATEHGRTPLHXASAQ 364

Query: 604 GHTDVADVLLQAGADLEHESEGGRTPLMKAARAG 637
           GH  + D+LL+ GAD++ E + G T L  A + G
Sbjct: 365 GHGHIVDLLLEKGADIDAEDDYGDTALSIADQFG 466

 Score = 48.5 bits (114), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 32/92 (34%), Positives = 52/92 (56%)
 Frame = +2

Query: 1241 NAQIETNRNTALTLACFQGRTEVVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVL 1300
             A +E   + AL +A  +G  ++ S L+   A+V    + G TPL  A++ G+  +  +L
Sbjct: 212  KAWLEERASVALAMAANRGLDKMCSQLIQTGADVNSATEHGRTPLHXASAQGHGHIVDLL 391

Query: 1301 LDKGADVNAPPVPSSRDTALTIAADKGHYKFC 1332
            L+KGAD++A       DTAL+I AD+  +K C
Sbjct: 392  LEKGADIDAE--DDYGDTALSI-ADQFGFKSC 478

 Score = 47.0 bits (110), Expect = 9e-05,   Method: Compositional matrix adjust.
 Identities = 30/78 (38%), Positives = 42/78 (53%), Gaps = 2/78 (2%)
 Frame = +2

Query: 596 ALTYACENGHTDVADVLLQAGADLEHESEGGRTPLMKAARAGHVCTVQFLISKGANVNRT 655
           AL  A   G   +   L+Q GAD+   +E GRTPL  A+  GH   V  L+ KGA+++  
Sbjct: 242 ALAMAANRGLDKMCSQLIQTGADVNSATEHGRTPLHXASAQGHGHIVDLLLEKGADID-- 415

Query: 656 TANNDH--TVLSLACAGG 671
            A +D+  T LS+A   G
Sbjct: 416 -AEDDYGDTALSIADQFG 466

 Score = 46.6 bits (109), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 32/100 (32%), Positives = 51/100 (51%)
 Frame = +2

Query: 318 AHKADVNAQSSTGNTALTYACAGGYVDVVKVLLESGASIEDHNENGHTPLMEAGSAGHVE 377
           A KA +  ++S    AL  A   G   +   L+++GA +    E+G TPL  A + GH  
Sbjct: 206 ARKAWLEERASV---ALAMAANRGLDKMCSQLIQTGADVNSATEHGRTPLHXASAQGHGH 376

Query: 378 VARLLLENGAGINTHSNEFKESALTLACYKGHLEMVRFLL 417
           +  LLLE GA I+   +++ ++AL++A   G     R L 
Sbjct: 377 IVDLLLEKGADIDA-EDDYGDTALSIADQFGFKSCGRXLF 493

 Score = 46.2 bits (108), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 28/73 (38%), Positives = 46/73 (63%)
 Frame = +2

Query: 1183 LSLAASGGYVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHTAAVKLLLDMGSDINA 1242
            L++AA+ G   +   L+  GA++NS T  + G +PL  A+  GH   V LLL+ G+DI+A
Sbjct: 245  LAMAANRGLDKMCSQLIQTGADVNSAT--EHGRTPLHXASAQGHGHIVDLLLEKGADIDA 418

Query: 1243 QIETNRNTALTLA 1255
            + +   +TAL++A
Sbjct: 419  EDDYG-DTALSIA 454

 Score = 42.7 bits (99), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 33/91 (36%), Positives = 46/91 (50%)
 Frame = +2

Query: 1270 RKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADVNAPPVPSSRDTALTIAADKGHY 1329
            RKA +E RA   L     AA+ G  ++   L+  GADVN+        T L  A+ +GH 
Sbjct: 209  RKAWLEERASVALAM---AANRGLDKMCSQLIQTGADVNSATEHGR--TPLHXASAQGHG 373

Query: 1330 KFCELLIGKGAHIDVRNKKGNTPLWLAANGG 1360
               +LL+ KGA ID  +  G+T L +A   G
Sbjct: 374  HIVDLLLEKGADIDAEDDYGDTALSIADQFG 466

 Score = 42.0 bits (97), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 22/57 (38%), Positives = 35/57 (61%)
 Frame = +2

Query: 467 LTLAACGGHVELAALLIERGASLEEVNDEGYTPLMEAAREGHEEMVALLLGQGANIN 523
           L +AA  G  ++ + LI+ GA +    + G TPL  A+ +GH  +V LLL +GA+I+
Sbjct: 245 LAMAANRGLDKMCSQLIQTGADVNSATEHGRTPLHXASAQGHGHIVDLLLEKGADID 415

 Score = 40.0 bits (92), Expect = 0.011,   Method: Compositional matrix adjust.
 Identities = 30/99 (30%), Positives = 49/99 (49%)
 Frame = +2

Query: 1101 RGASIEHRDKKGFTPLILAATAGHVGVVEILLDNGADIEAQSERTKDTPLSLACSGGRQE 1160
            R A +E R       L +AA  G   +   L+  GAD+ + +E  + TPL  A + G   
Sbjct: 209  RKAWLEER---ASVALAMAANRGLDKMCSQLIQTGADVNSATEHGR-TPLHXASAQGHGH 376

Query: 1161 VVELLLARGANKEHRNVSDYTPLSLAASGGYVNIIKILL 1199
            +V+LLL +GA+ +  +    T LS+A   G+ +  + L 
Sbjct: 377  IVDLLLEKGADIDAEDDYGDTALSIADQFGFKSCGRXLF 493

 Score = 38.5 bits (88), Expect = 0.034,   Method: Compositional matrix adjust.
 Identities = 25/80 (31%), Positives = 40/80 (50%), Gaps = 6/80 (7%)
 Frame = +2

Query: 400 ALTLACYKGHLEMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMP 459
           AL +A  +G  +M   L++ GAD    T+   T L  A   GH  +  LLL+ GA ++  
Sbjct: 242 ALAMAANRGLDKMCSQLIQTGADVNSATEHGRTPLHXASAQGHGHIVDLLLEKGADIDAE 421

Query: 460 ADSFESPLTLA------ACG 473
            D  ++ L++A      +CG
Sbjct: 422 DDYGDTALSIADQFGFKSCG 481

 Score = 34.3 bits (77), Expect = 0.75,   Method: Compositional matrix adjust.
 Identities = 23/84 (27%), Positives = 41/84 (48%)
 Frame = +2

Query: 1347 KKGNTPLWLAANGGHLDVVQLLVQATADVDAADNRKITPLMAAFRKGHVKVVRYLVKEVN 1406
            ++ +  L +AAN G   +   L+Q  ADV++A     TPL  A  +GH  +V  L+++  
Sbjct: 227  ERASVALAMAANRGLDKMCSQLIQTGADVNSATEHGRTPLHXASAQGHGHIVDLLLEKGA 406

Query: 1407 QFPSDSECMRYIATITDKEMLKKC 1430
               ++ +      +I D+   K C
Sbjct: 407  DIDAEDDYGDTALSIADQFGFKSC 478

 Score = 34.3 bits (77), Expect = 0.77,   Method: Compositional matrix adjust.
 Identities = 32/104 (30%), Positives = 46/104 (44%)
 Frame = +2

Query: 347 KVLLESGASIEDHNENGHTPLMEAGSAGHVEVARLLLENGAGINTHSNEFKESALTLACY 406
           K  LE  AS+          L  A + G  ++   L++ GA +N+ + E   + L  A  
Sbjct: 212 KAWLEERASV---------ALAMAANRGLDKMCSQLIQTGADVNS-ATEHGRTPLHXASA 361

Query: 407 KGHLEMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLL 450
           +GH  +V  LLE GAD + + D   TAL  A   G     R L 
Sbjct: 362 QGHGHIVDLLLEKGADIDAEDDYGDTALSIADQFGFKSCGRXLF 493

 Score = 33.9 bits (76), Expect = 0.78,   Method: Compositional matrix adjust.
 Identities = 26/63 (41%), Positives = 31/63 (49%)
 Frame = +2

Query: 645 LISKGANVNRTTANNDHTVLSLACAGGHLAVVELLLAHGADPTHRLKDGSTMLIEAAKGG 704
           LI  GA+VN  T +   T L  A A GH  +V+LLL  GAD       G T L  A + G
Sbjct: 290 LIQTGADVNSATEHG-RTPLHXASAQGHGHIVDLLLEKGADIDAEDDYGDTALSIADQFG 466

Query: 705 HTS 707
             S
Sbjct: 467 FKS 475
>30978
          Length = 566

 Score = 48.9 bits (115), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 29/82 (35%), Positives = 45/82 (54%), Gaps = 1/82 (1%)
 Frame = -2

Query: 317 LAHKADVNAQSSTGNTALTYACAGGYVDVVKVLL-ESGASIEDHNENGHTPLMEAGSAGH 375
           L+++  VN     G+T L +A  GG++D ++VLL E    +   N+ G T L  A    H
Sbjct: 511 LSNRVSVNGLDKAGSTPLHWAGHGGHMDCLQVLLSEPKCEVNVQNKLGDTALHSAAWKNH 332

Query: 376 VEVARLLLENGAGINTHSNEFK 397
           VE  ++LL  GA ++  +NE K
Sbjct: 331 VEAVKMLLGKGARVDLRNNEKK 266

 Score = 47.8 bits (112), Expect = 6e-05,   Method: Compositional matrix adjust.
 Identities = 27/67 (40%), Positives = 41/67 (61%), Gaps = 1/67 (1%)
 Frame = -2

Query: 295 KGDITPLMAAANGGHVKIVKLLLAH-KADVNAQSSTGNTALTYACAGGYVDVVKVLLESG 353
           K   TPL  A +GGH+  +++LL+  K +VN Q+  G+TAL  A    +V+ VK+LL  G
Sbjct: 478 KAGSTPLHWAGHGGHMDCLQVLLSEPKCEVNVQNKLGDTALHSAAWKNHVEAVKMLLGKG 299

Query: 354 ASIEDHN 360
           A ++  N
Sbjct: 298 ARVDLRN 278

 Score = 45.8 bits (107), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 36/98 (36%), Positives = 53/98 (54%), Gaps = 3/98 (3%)
 Frame = -2

Query: 1252 LTLA-CFQGRTE-VVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDK-GADVN 1308
            L+LA C + R    ++  L  + +V    K G TPL  A  GG+ +  +VLL +   +VN
Sbjct: 565  LSLA*CCKTRQH*FLTECLSNRVSVNGLDKAGSTPLHWAGHGGHMDCLQVLLSEPKCEVN 386

Query: 1309 APPVPSSRDTALTIAADKGHYKFCELLIGKGAHIDVRN 1346
                    DTAL  AA K H +  ++L+GKGA +D+RN
Sbjct: 385  VQNKLG--DTALHSAAWKNHVEAVKMLLGKGARVDLRN 278

 Score = 41.6 bits (96), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 28/86 (32%), Positives = 47/86 (54%), Gaps = 1/86 (1%)
 Frame = -2

Query: 350 LESGASIEDHNENGHTPLMEAGSAGHVEVARLLL-ENGAGINTHSNEFKESALTLACYKG 408
           L +  S+   ++ G TPL  AG  GH++  ++LL E    +N   N+  ++AL  A +K 
Sbjct: 511 LSNRVSVNGLDKAGSTPLHWAGHGGHMDCLQVLLSEPKCEVNV-QNKLGDTALHSAAWKN 335

Query: 409 HLEMVRFLLEAGADQEHKTDEMHTAL 434
           H+E V+ LL  GA  + + +E   A+
Sbjct: 334 HVEAVKMLLGKGARVDLRNNEKKLAV 257

 Score = 40.4 bits (93), Expect = 0.009,   Method: Compositional matrix adjust.
 Identities = 31/96 (32%), Positives = 51/96 (53%), Gaps = 1/96 (1%)
 Frame = -2

Query: 1181 TPLSLAASGGYVNIIKILLNA-GAEINSRTGSKLGISPLMLAAMNGHTAAVKLLLDMGSD 1239
            TPL  A  GG+++ +++LL+    E+N +  +KLG + L  AA   H  AVK+LL  G+ 
Sbjct: 466  TPLHWAGHGGHMDCLQVLLSEPKCEVNVQ--NKLGDTALHSAAWKNHVEAVKMLLGKGAR 293

Query: 1240 INAQIETNRNTALTLACFQGRTEVVSLLLDRKANVE 1275
            ++      RN    LA    +   V+ +L + A V+
Sbjct: 292  VDL-----RNNEKKLAVELTKDPEVAAMLRQAAGVQ 200

 Score = 38.9 bits (89), Expect = 0.028,   Method: Compositional matrix adjust.
 Identities = 22/58 (37%), Positives = 35/58 (60%), Gaps = 1/58 (1%)
 Frame = -2

Query: 1346 NKKGNTPLWLAANGGHLDVVQ-LLVQATADVDAADNRKITPLMAAFRKGHVKVVRYLV 1402
            +K G+TPL  A +GGH+D +Q LL +   +V+  +    T L +A  K HV+ V+ L+
Sbjct: 481  DKAGSTPLHWAGHGGHMDCLQVLLSEPKCEVNVQNKLGDTALHSAAWKNHVEAVKMLL 308

 Score = 37.7 bits (86), Expect = 0.058,   Method: Compositional matrix adjust.
 Identities = 29/87 (33%), Positives = 43/87 (49%), Gaps = 1/87 (1%)
 Frame = -2

Query: 1091 HEELVQTLLERGASIEHRDKKGFTPLILAATAGHVGVVEILLDN-GADIEAQSERTKDTP 1149
            H  L + L  R  S+   DK G TPL  A   GH+  +++LL     ++  Q+ +  DT 
Sbjct: 532  H*FLTECLSNR-VSVNGLDKAGSTPLHWAGHGGHMDCLQVLLSEPKCEVNVQN-KLGDTA 359

Query: 1150 LSLACSGGRQEVVELLLARGANKEHRN 1176
            L  A      E V++LL +GA  + RN
Sbjct: 358  LHSAAWKNHVEAVKMLLGKGARVDLRN 278

 Score = 36.2 bits (82), Expect = 0.17,   Method: Compositional matrix adjust.
 Identities = 24/69 (34%), Positives = 35/69 (50%), Gaps = 1/69 (1%)
 Frame = -2

Query: 586 VHATTATGDTALTYACENGHTDVADVLL-QAGADLEHESEGGRTPLMKAARAGHVCTVQF 644
           V+     G T L +A   GH D   VLL +   ++  +++ G T L  AA   HV  V+ 
Sbjct: 493 VNGLDKAGSTPLHWAGHGGHMDCLQVLLSEPKCEVNVQNKLGDTALHSAAWKNHVEAVKM 314

Query: 645 LISKGANVN 653
           L+ KGA V+
Sbjct: 313 LLGKGARVD 287

 Score = 34.7 bits (78), Expect = 0.51,   Method: Compositional matrix adjust.
 Identities = 21/61 (34%), Positives = 31/61 (50%), Gaps = 1/61 (1%)
 Frame = -2

Query: 561 STPLMEAAQEGHLELVKYLLAA-GANVHATTATGDTALTYACENGHTDVADVLLQAGADL 619
           STPL  A   GH++ ++ LL+     V+     GDTAL  A    H +   +LL  GA +
Sbjct: 469 STPLHWAGHGGHMDCLQVLLSEPKCEVNVQNKLGDTALHSAAWKNHVEAVKMLLGKGARV 290

Query: 620 E 620
           +
Sbjct: 289 D 287
>09180
          Length = 610

 Score = 47.8 bits (112), Expect = 6e-05,   Method: Compositional matrix adjust.
 Identities = 32/86 (37%), Positives = 43/86 (50%), Gaps = 2/86 (2%)
 Frame = +3

Query: 1273 NVEHRA--KTGLTPLMEAASGGYAEVGRVLLDKGADVNAPPVPSSRDTALTIAADKGHYK 1330
            N+E  A  KTG T L  +A+ GY  V  VLL  G D+NA        T+L  A   G   
Sbjct: 135  NIEDNAHPKTGATALHVSAAKGYINVMNVLLQAGVDINAQDADGW--TSLHAAVHWGQED 308

Query: 1331 FCELLIGKGAHIDVRNKKGNTPLWLA 1356
             C++L+     +DV+N  G+T   LA
Sbjct: 309  SCQVLVDHFCDMDVKNNAGHTVFDLA 386

 Score = 44.3 bits (103), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 34/107 (31%), Positives = 53/107 (49%), Gaps = 2/107 (1%)
 Frame = +3

Query: 1347 KKGNTPLWLAANGGHLDVVQLLVQATADVDAADNRKITPLMAAFRKGHVKVVRYLVKEVN 1406
            K G T L ++A  G+++V+ +L+QA  D++A D    T L AA   G     + LV    
Sbjct: 159  KTGATALHVSAAKGYINVMNVLLQAGVDINAQDADGWTSLHAAVHWGQEDSCQVLVDHFC 338

Query: 1407 QFPSDSECMRYIATITDKEMLKKCHLCMESI--VQAKDRQAAEANKN 1451
                 +     +  + DKEMLK     +E +   QAK R A+E+N +
Sbjct: 339  DMDVKNNAGHTVFDLADKEMLK----VLEELKKKQAKLRTASESNSD 467

 Score = 42.0 bits (97), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 23/71 (32%), Positives = 40/71 (56%)
 Frame = +3

Query: 324 NAQSSTGNTALTYACAGGYVDVVKVLLESGASIEDHNENGHTPLMEAGSAGHVEVARLLL 383
           NA   TG TAL  + A GY++V+ VLL++G  I   + +G T L  A   G  +  ++L+
Sbjct: 147 NAHPKTGATALHVSAAKGYINVMNVLLQAGVDINAQDADGWTSLHAAVHWGQEDSCQVLV 326

Query: 384 ENGAGINTHSN 394
           ++   ++  +N
Sbjct: 327 DHFCDMDVKNN 359

 Score = 42.0 bits (97), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 27/76 (35%), Positives = 38/76 (50%)
 Frame = +3

Query: 592 TGDTALTYACENGHTDVADVLLQAGADLEHESEGGRTPLMKAARAGHVCTVQFLISKGAN 651
           TG TAL  +   G+ +V +VLLQAG D+  +   G T L  A   G   + Q L+    +
Sbjct: 162 TGATALHVSAAKGYINVMNVLLQAGVDINAQDADGWTSLHAAVHWGQEDSCQVLVDHFCD 341

Query: 652 VNRTTANNDHTVLSLA 667
           ++    N  HTV  LA
Sbjct: 342 MD-VKNNAGHTVFDLA 386

 Score = 42.0 bits (97), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 36/119 (30%), Positives = 57/119 (47%)
 Frame = +3

Query: 1295 EVGRVLLDKGADVNAPPVPSSRDTALTIAADKGHYKFCELLIGKGAHIDVRNKKGNTPLW 1354
            +  R L +K  + NA P   +  TAL ++A KG+     +L+  G  I+ ++  G T L 
Sbjct: 108  DANRWLQNKNIEDNAHPKTGA--TALHVSAAKGYINVMNVLLQAGVDINAQDADGWTSLH 281

Query: 1355 LAANGGHLDVVQLLVQATADVDAADNRKITPLMAAFRKGHVKVVRYLVKEVNQFPSDSE 1413
             A + G  D  Q+LV    D+D  +N   T    A  K  +KV+  L K+  +  + SE
Sbjct: 282  AAVHWGQEDSCQVLVDHFCDMDVKNNAGHTVFDLA-DKEMLKVLEELKKKQAKLRTASE 455

 Score = 32.3 bits (72), Expect = 2.7,   Method: Compositional matrix adjust.
 Identities = 25/95 (26%), Positives = 47/95 (49%)
 Frame = +3

Query: 257 NEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGIKGDITPLMAAANGGHVKIVKLL 316
           N H + G + L ++ + GY  +  VLL    ++  +   G  T L AA + G     ++L
Sbjct: 147 NAHPKTGATALHVSAAKGYINVMNVLLQAGVDINAQDADG-WTSLHAAVHWGQEDSCQVL 323

Query: 317 LAHKADVNAQSSTGNTALTYACAGGYVDVVKVLLE 351
           + H  D++ +++ G+T    A      +++KVL E
Sbjct: 324 VDHFCDMDVKNNAGHTVFDLADK----EMLKVLEE 416
>25464
          Length = 440

 Score = 47.8 bits (112), Expect = 6e-05,   Method: Compositional matrix adjust.
 Identities = 31/93 (33%), Positives = 50/93 (53%), Gaps = 4/93 (4%)
 Frame = -3

Query: 321 ADVNAQSSTGNTALTYACAGGYVDVVKVLL-ESGASIEDHNENGHTPLMEAGSAGHVEVA 379
           A +N + S G TAL+YAC  G  D+V+ +L E    I + + +G+TP+  A  + +  + 
Sbjct: 438 AYLNVRDSMGRTALSYACLNGRQDIVRCILKEDVLDINEPDNDGNTPIHHAAISANPNIV 259

Query: 380 RLLLE--NGAGIN-THSNEFKESALTLACYKGH 409
           R+L E     G+N    N+   + L LAC  G+
Sbjct: 258 RMLAEAFYKFGLNPDKRNKLGYTPLLLACKGGN 160

 Score = 43.5 bits (101), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 38/120 (31%), Positives = 57/120 (47%), Gaps = 6/120 (5%)
 Frame = -3

Query: 584 ANVHATTATGDTALTYACENGHTDVADVLLQAGA-DLEHESEGGRTPLMKAARAGHVCTV 642
           A ++   + G TAL+YAC NG  D+   +L+    D+      G TP+  AA + +   V
Sbjct: 438 AYLNVRDSMGRTALSYACLNGRQDIVRCILKEDVLDINEPDNDGNTPIHHAAISANPNIV 259

Query: 643 QFL----ISKGANVNRTTANNDHTVLSLACAGG-HLAVVELLLAHGADPTHRLKDGSTML 697
           + L       G N ++      +T L LAC GG +++   LL    A PT  L+DG   L
Sbjct: 258 RMLAEAFYKFGLNPDKRNKLG-YTPLLLACKGGNYVSAYTLLTTTKASPT--LRDGEFHL 88

 Score = 40.8 bits (94), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 30/90 (33%), Positives = 46/90 (51%), Gaps = 3/90 (3%)
 Frame = -3

Query: 1148 TPLSLACSGGRQEVVELLLARGANKEHRNVSD-YTPLSLAASGGYVNIIKILLNAGAE-- 1204
            T LS AC  GRQ++V  +L       +   +D  TP+  AA     NI+++L  A  +  
Sbjct: 405  TALSYACLNGRQDIVRCILKEDVLDINEPDNDGNTPIHHAAISANPNIVRMLAEAFYKFG 226

Query: 1205 INSRTGSKLGISPLMLAAMNGHTAAVKLLL 1234
            +N    +KLG +PL+LA   G+  +   LL
Sbjct: 225  LNPDKRNKLGYTPLLLACKGGNYVSAYTLL 136

 Score = 37.7 bits (86), Expect = 0.060,   Method: Compositional matrix adjust.
 Identities = 34/124 (27%), Positives = 47/124 (37%), Gaps = 1/124 (0%)
 Frame = -3

Query: 1250 TALTLACFQGRTEVVSLLLDRKA-NVEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADVN 1308
            TAL+ AC  GR ++V  +L     ++      G TP+  AA      + R+L +      
Sbjct: 405  TALSYACLNGRQDIVRCILKEDVLDINEPDNDGNTPIHHAAISANPNIVRMLAE------ 244

Query: 1309 APPVPSSRDTALTIAADKGHYKFCELLIGKGAHIDVRNKKGNTPLWLAANGGHLDVVQLL 1368
                                YKF       G + D RNK G TPL LA  GG+      L
Sbjct: 243  ------------------AFYKF-------GLNPDKRNKLGYTPLLLACKGGNYVSAYTL 139

Query: 1369 VQAT 1372
            +  T
Sbjct: 138  LTTT 127

 Score = 37.4 bits (85), Expect = 0.089,   Method: Compositional matrix adjust.
 Identities = 24/82 (29%), Positives = 42/82 (51%), Gaps = 5/82 (6%)
 Frame = -3

Query: 432 TALMEACMDGHVEVARLLLDSGA-QVNMPADSFESPLTLAACGGHVELAALLIER----G 486
           TAL  AC++G  ++ R +L      +N P +   +P+  AA   +  +  +L E     G
Sbjct: 405 TALSYACLNGRQDIVRCILKEDVLDINEPDNDGNTPIHHAAISANPNIVRMLAEAFYKFG 226

Query: 487 ASLEEVNDEGYTPLMEAAREGH 508
            + ++ N  GYTPL+ A + G+
Sbjct: 225 LNPDKRNKLGYTPLLLACKGGN 160

 Score = 35.4 bits (80), Expect = 0.34,   Method: Compositional matrix adjust.
 Identities = 27/90 (30%), Positives = 44/90 (48%), Gaps = 5/90 (5%)
 Frame = -3

Query: 299 TPLMAAANGGHVKIVKLLLAHKA-DVNAQSSTGNTALTYACAGGYVDVVKVLLES----G 353
           T L  A   G   IV+ +L     D+N   + GNT + +A      ++V++L E+    G
Sbjct: 405 TALSYACLNGRQDIVRCILKEDVLDINEPDNDGNTPIHHAAISANPNIVRMLAEAFYKFG 226

Query: 354 ASIEDHNENGHTPLMEAGSAGHVEVARLLL 383
            + +  N+ G+TPL+ A   G+   A  LL
Sbjct: 225 LNPDKRNKLGYTPLLLACKGGNYVSAYTLL 136
>03467
          Length = 2192

 Score = 47.8 bits (112), Expect = 7e-05,   Method: Composition-based stats.
 Identities = 19/60 (31%), Positives = 34/60 (56%)
 Frame = -2

Query: 1730 STVISRVIGRGGCNINAIRECTGAHIDIDKQKDKTGDRIITIRGGTESTRQATQLINALI 1789
            ST + R+IGRGG  I  I++ TG  +++ +  D  G   + +RG     + A Q+I+ ++
Sbjct: 1732 STFVGRIIGRGGSRIREIQDSTGCRVNVSRDGDDNGQTEVELRGTLSEVQHAKQMIDDIV 1553

 Score = 32.7 bits (73), Expect = 2.0,   Method: Composition-based stats.
 Identities = 13/60 (21%), Positives = 34/60 (56%)
 Frame = -2

Query: 1735 RVIGRGGCNINAIRECTGAHIDIDKQKDKTGDRIITIRGGTESTRQATQLINALIKDPDK 1794
            ++IGRGG  I  ++  +   I +++  +  G R + + G  ++  +A  +I+ ++++ D+
Sbjct: 2023 KIIGRGGNKIRELQIESRCQIKVNRDDEPDGTRRVDLSGSDDAIAKAKDMIHQVLEEDDR 1844
>22305
          Length = 426

 Score = 46.6 bits (109), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 28/70 (40%), Positives = 36/70 (51%), Gaps = 1/70 (1%)
 Frame = -3

Query: 1262 EVVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADVNAPPVPSSRDTA-L 1320
            ++ + LL+R  +   R   G+ PL EA      EVGRVLL  GAD   P VP   +   L
Sbjct: 343  DITTALLERGCSANERNHWGILPLHEALCWENVEVGRVLLQYGAD---PNVPCETNVVPL 173

Query: 1321 TIAADKGHYK 1330
            T AA  GH +
Sbjct: 172  TFAARTGHIR 143

 Score = 39.7 bits (91), Expect = 0.014,   Method: Compositional matrix adjust.
 Identities = 27/68 (39%), Positives = 33/68 (48%)
 Frame = -3

Query: 344 DVVKVLLESGASIEDHNENGHTPLMEAGSAGHVEVARLLLENGAGINTHSNEFKESALTL 403
           D+   LLE G S  + N  G  PL EA    +VEV R+LL+ GA  N    E     LT 
Sbjct: 343 DITTALLERGCSANERNHWGILPLHEALCWENVEVGRVLLQYGADPNV-PCETNVVPLTF 167

Query: 404 ACYKGHLE 411
           A   GH+ 
Sbjct: 166 AARTGHIR 143

 Score = 38.9 bits (89), Expect = 0.026,   Method: Compositional matrix adjust.
 Identities = 24/62 (38%), Positives = 31/62 (50%)
 Frame = -3

Query: 416 LLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGH 475
           LLE G     +       L EA    +VEV R+LL  GA  N+P ++   PLT AA  GH
Sbjct: 328 LLERGCSANERNHWGILPLHEALCWENVEVGRVLLQYGADPNVPCETNVVPLTFAARTGH 149

Query: 476 VE 477
           + 
Sbjct: 148 IR 143

 Score = 35.4 bits (80), Expect = 0.29,   Method: Compositional matrix adjust.
 Identities = 24/65 (36%), Positives = 30/65 (46%)
 Frame = -3

Query: 1093 ELVQTLLERGASIEHRDKKGFTPLILAATAGHVGVVEILLDNGADIEAQSERTKDTPLSL 1152
            ++   LLERG S   R+  G  PL  A    +V V  +LL  GAD     E T   PL+ 
Sbjct: 343  DITTALLERGCSANERNHWGILPLHEALCWENVEVGRVLLQYGADPNVPCE-TNVVPLTF 167

Query: 1153 ACSGG 1157
            A   G
Sbjct: 166  AARTG 152

 Score = 33.1 bits (74), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 27/82 (32%), Positives = 39/82 (47%)
 Frame = -3

Query: 1160 EVVELLLARGANKEHRNVSDYTPLSLAASGGYVNIIKILLNAGAEINSRTGSKLGISPLM 1219
            ++   LL RG +   RN     PL  A     V + ++LL  GA+ N     +  + PL 
Sbjct: 343  DITTALLERGCSANERNHWGILPLHEALCWENVEVGRVLLQYGADPN--VPCETNVVPLT 170

Query: 1220 LAAMNGHTAAVKLLLDMGSDIN 1241
             AA  GH    +LLL  G+D+N
Sbjct: 169  FAARTGHIRLAQLLLAAGADVN 104
>30463
          Length = 412

 Score = 46.6 bits (109), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 32/85 (37%), Positives = 45/85 (52%)
 Frame = -1

Query: 1081 TALTLACAGGHEELVQTLLERGASIEHRDKKGFTPLILAATAGHVGVVEILLDNGADIEA 1140
            TA  LA   GH   V  L   GASI+ R     TPL LA++AGH+  V+ L+ N A + A
Sbjct: 382  TATHLAAMNGHSNAVMVLNIMGASIDCRTVDKQTPLHLASSAGHIECVKCLVANKASLTA 203

Query: 1141 QSERTKDTPLSLACSGGRQEVVELL 1165
            +   ++ T   LA   G+ +V + L
Sbjct: 202  EDAFSR-TAYDLADQYGQNDVADFL 131

 Score = 46.2 bits (108), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 33/88 (37%), Positives = 45/88 (51%)
 Frame = -1

Query: 329 TGNTALTYACAGGYVDVVKVLLESGASIEDHNENGHTPLMEAGSAGHVEVARLLLENGAG 388
           TG TA   A   G+ + V VL   GASI+    +  TPL  A SAGH+E  + L+ N A 
Sbjct: 391 TGYTATHLAAMNGHSNAVMVLNIMGASIDCRTVDKQTPLHLASSAGHIECVKCLVANKAS 212

Query: 389 INTHSNEFKESALTLACYKGHLEMVRFL 416
           + T  + F  +A  LA   G  ++  FL
Sbjct: 211 L-TAEDAFSRTAYDLADQYGQNDVADFL 131

 Score = 40.8 bits (94), Expect = 0.007,   Method: Composition-based stats.
 Identities = 38/128 (29%), Positives = 49/128 (38%)
 Frame = -1

Query: 496 GYTPLMEAAREGHEEMVALLLGQGANINXXXXXXXXXXXXXXCCGGFLEVADFLIKAGAD 555
           GYT    AA  GH   V +L   GA+I+                                
Sbjct: 388 GYTATHLAAMNGHSNAVMVLNIMGASIDCRTVDK-------------------------- 287

Query: 556 IELGCSTPLMEAAQEGHLELVKYLLAAGANVHATTATGDTALTYACENGHTDVADVLLQA 615
                 TPL  A+  GH+E VK L+A  A++ A  A   TA   A + G  DVAD L   
Sbjct: 286 -----QTPLHLASSAGHIECVKCLVANKASLTAEDAFSRTAYDLADQYGQNDVADFLHHC 122

Query: 616 GADLEHES 623
             DL++ S
Sbjct: 121 LLDLDNPS 98

 Score = 40.4 bits (93), Expect = 0.009,   Method: Compositional matrix adjust.
 Identities = 30/84 (35%), Positives = 40/84 (47%)
 Frame = -1

Query: 1318 TALTIAADKGHYKFCELLIGKGAHIDVRNKKGNTPLWLAANGGHLDVVQLLVQATADVDA 1377
            TA  +AA  GH     +L   GA ID R     TPL LA++ GH++ V+ LV   A + A
Sbjct: 382  TATHLAAMNGHSNAVMVLNIMGASIDCRTVDKQTPLHLASSAGHIECVKCLVANKASLTA 203

Query: 1378 ADNRKITPLMAAFRKGHVKVVRYL 1401
             D    T    A + G   V  +L
Sbjct: 202  EDAFSRTAYDLADQYGQNDVADFL 131

 Score = 38.9 bits (89), Expect = 0.025,   Method: Composition-based stats.
 Identities = 30/87 (34%), Positives = 41/87 (47%)
 Frame = -1

Query: 1112 GFTPLILAATAGHVGVVEILLDNGADIEAQSERTKDTPLSLACSGGRQEVVELLLARGAN 1171
            G+T   LAA  GH   V +L   GA I+ ++   K TPL LA S G  E V+ L+A  A+
Sbjct: 388  GYTATHLAAMNGHSNAVMVLNIMGASIDCRTV-DKQTPLHLASSAGHIECVKCLVANKAS 212

Query: 1172 KEHRNVSDYTPLSLAASGGYVNIIKIL 1198
                +    T   LA   G  ++   L
Sbjct: 211  LTAEDAFSRTAYDLADQYGQNDVADFL 131

 Score = 38.9 bits (89), Expect = 0.026,   Method: Composition-based stats.
 Identities = 24/61 (39%), Positives = 35/61 (57%)
 Frame = -1

Query: 1214 GISPLMLAAMNGHTAAVKLLLDMGSDINAQIETNRNTALTLACFQGRTEVVSLLLDRKAN 1273
            G +   LAAMNGH+ AV +L  MG+ I+ +   ++ T L LA   G  E V  L+  KA+
Sbjct: 388  GYTATHLAAMNGHSNAVMVLNIMGASIDCRT-VDKQTPLHLASSAGHIECVKCLVANKAS 212

Query: 1274 V 1274
            +
Sbjct: 211  L 209

 Score = 37.4 bits (85), Expect = 0.080,   Method: Compositional matrix adjust.
 Identities = 28/81 (34%), Positives = 42/81 (51%)
 Frame = -1

Query: 269 LACSAGYYELAQVLLAMHANVEDRGIKGDITPLMAAANGGHVKIVKLLLAHKADVNAQSS 328
           LA   G+     VL  M A+++ R +    TPL  A++ GH++ VK L+A+KA + A+ +
Sbjct: 370 LAAMNGHSNAVMVLNIMGASIDCRTVDKQ-TPLHLASSAGHIECVKCLVANKASLTAEDA 194

Query: 329 TGNTALTYACAGGYVDVVKVL 349
              TA   A   G  DV   L
Sbjct: 193 FSRTAYDLADQYGQNDVADFL 131

 Score = 35.8 bits (81), Expect = 0.25,   Method: Compositional matrix adjust.
 Identities = 23/63 (36%), Positives = 36/63 (57%)
 Frame = -1

Query: 590 TATGDTALTYACENGHTDVADVLLQAGADLEHESEGGRTPLMKAARAGHVCTVQFLISKG 649
           T TG TA   A  NGH++   VL   GA ++  +   +TPL  A+ AGH+  V+ L++  
Sbjct: 397 TPTGYTATHLAAMNGHSNAVMVLNIMGASIDCRTVDKQTPLHLASSAGHIECVKCLVANK 218

Query: 650 ANV 652
           A++
Sbjct: 217 ASL 209

 Score = 33.5 bits (75), Expect = 1.2,   Method: Composition-based stats.
 Identities = 23/76 (30%), Positives = 33/76 (43%)
 Frame = -1

Query: 1349 GNTPLWLAANGGHLDVVQLLVQATADVDAADNRKITPLMAAFRKGHVKVVRYLVKEVNQF 1408
            G T   LAA  GH + V +L    A +D     K TPL  A   GH++ V+ LV      
Sbjct: 388  GYTATHLAAMNGHSNAVMVLNIMGASIDCRTVDKQTPLHLASSAGHIECVKCLVANKASL 209

Query: 1409 PSDSECMRYIATITDK 1424
             ++    R    + D+
Sbjct: 208  TAEDAFSRTAYDLADQ 161

 Score = 33.1 bits (74), Expect = 1.4,   Method: Compositional matrix adjust.
 Identities = 20/59 (33%), Positives = 30/59 (50%)
 Frame = -1

Query: 431 HTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALLIERGASL 489
           +TA   A M+GH     +L   GA ++      ++PL LA+  GH+E    L+   ASL
Sbjct: 385 YTATHLAAMNGHSNAVMVLNIMGASIDCRTVDKQTPLHLASSAGHIECVKCLVANKASL 209

 Score = 30.8 bits (68), Expect = 8.4,   Method: Composition-based stats.
 Identities = 24/79 (30%), Positives = 29/79 (36%)
 Frame = -1

Query: 567 AAQEGHLELVKYLLAAGANVHATTATGDTALTYACENGHTDVADVLLQAGADLEHESEGG 626
           AA  GH   V  L   GA++   T    T L  A   GH +    L+   A L  E    
Sbjct: 367 AAMNGHSNAVMVLNIMGASIDCRTVDKQTPLHLASSAGHIECVKCLVANKASLTAEDAFS 188

Query: 627 RTPLMKAARAGHVCTVQFL 645
           RT    A + G      FL
Sbjct: 187 RTAYDLADQYGQNDVADFL 131

 Score = 30.8 bits (68), Expect = 8.5,   Method: Composition-based stats.
 Identities = 20/53 (37%), Positives = 30/53 (56%)
 Frame = -1

Query: 237 ACSEGDVNAVRKLLIEGRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANV 289
           A   G  NAV  L I G S++  T + ++ L LA SAG+ E  + L+A  A++
Sbjct: 367 AAMNGHSNAVMVLNIMGASIDCRTVDKQTPLHLASSAGHIECVKCLVANKASL 209
>28691
          Length = 562

 Score = 46.6 bits (109), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 39/103 (37%), Positives = 53/103 (51%), Gaps = 4/103 (3%)
 Frame = +1

Query: 1098 LLERGASIEHRDKKGFTPLILAATAGHVGVVEILLDNGADIEAQSERT--KDTPLSLACS 1155
            LL + AS+E   K G   L LAA   HV  + +L+  GAD+ A+   T   +T L  A S
Sbjct: 82   LLRQLASVE--SKSGLPALHLAAKNKHVDCIPVLVQAGADVNAKGPSTIKGNTALHEAVS 255

Query: 1156 GGRQEV--VELLLARGANKEHRNVSDYTPLSLAASGGYVNIIK 1196
             G   V  V+ LL+ GA++   N    T   LA+  GY NI+K
Sbjct: 256  VGASNVDSVDALLSCGADQNIXNEKGETAYDLASKAGYENIVK 384

 Score = 39.3 bits (90), Expect = 0.020,   Method: Compositional matrix adjust.
 Identities = 37/108 (34%), Positives = 56/108 (51%), Gaps = 3/108 (2%)
 Frame = +1

Query: 1267 LLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADVNAP-PVPSSRDTALTIAAD 1325
            LL + A+VE  +K+GL  L  AA   + +   VL+  GADVNA  P     +TAL  A  
Sbjct: 82   LLRQLASVE--SKSGLPALHLAAKNKHVDCIPVLVQAGADVNAKGPSTIKGNTALHEAVS 255

Query: 1326 KG--HYKFCELLIGKGAHIDVRNKKGNTPLWLAANGGHLDVVQLLVQA 1371
             G  +    + L+  GA  ++ N+KG T   LA+  G+ ++V+    A
Sbjct: 256  VGASNVDSVDALLSCGADQNIXNEKGETAYDLASKAGYENIVKRFAAA 399

 Score = 33.5 bits (75), Expect = 1.0,   Method: Compositional matrix adjust.
 Identities = 31/91 (34%), Positives = 45/91 (49%), Gaps = 5/91 (5%)
 Frame = +1

Query: 596 ALTYACENGHTDVADVLLQAGADLEHE---SEGGRTPLMKAARAG--HVCTVQFLISKGA 650
           AL  A +N H D   VL+QAGAD+  +   +  G T L +A   G  +V +V  L+S GA
Sbjct: 127 ALHLAAKNKHVDCIPVLVQAGADVNAKGPSTIKGNTALHEAVSVGASNVDSVDALLSCGA 306

Query: 651 NVNRTTANNDHTVLSLACAGGHLAVVELLLA 681
           + N      + T   LA   G+  +V+   A
Sbjct: 307 DQNIXNEKGE-TAYDLASKAGYENIVKRFAA 396

 Score = 32.3 bits (72), Expect = 2.3,   Method: Compositional matrix adjust.
 Identities = 30/90 (33%), Positives = 42/90 (46%), Gaps = 4/90 (4%)
 Frame = +1

Query: 1211 SKLGISPLMLAAMNGHTAAVKLLLDMGSDINAQ--IETNRNTALTLACFQGRTEV--VSL 1266
            SK G+  L LAA N H   + +L+  G+D+NA+       NTAL  A   G + V  V  
Sbjct: 109  SKSGLPALHLAAKNKHVDCIPVLVQAGADVNAKGPSTIKGNTALHEAVSVGASNVDSVDA 288

Query: 1267 LLDRKANVEHRAKTGLTPLMEAASGGYAEV 1296
            LL   A+     + G T    A+  GY  +
Sbjct: 289  LLSCGADQNIXNEKGETAYDLASKAGYENI 378

 Score = 31.6 bits (70), Expect = 4.9,   Method: Compositional matrix adjust.
 Identities = 17/34 (50%), Positives = 22/34 (64%)
 Frame = +1

Query: 1344 VRNKKGNTPLWLAANGGHLDVVQLLVQATADVDA 1377
            V +K G   L LAA   H+D + +LVQA ADV+A
Sbjct: 103  VESKSGLPALHLAAKNKHVDCIPVLVQAGADVNA 204
>27108
          Length = 449

 Score = 45.8 bits (107), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 40/127 (31%), Positives = 54/127 (42%), Gaps = 1/127 (0%)
 Frame = -3

Query: 394 NEFKESALTLACYKGHLEMVRFLLEA-GADQEHKTDEMHTALMEACMDGHVEVARLLLDS 452
           N   E+ L  A  K +L +++ LL   G D   +     TAL EAC  GH+E AR LL  
Sbjct: 396 NHKGETMLIRAAIKNNLSLLKHLLTVPGVDINSQDYAGWTALHEACNHGHLECARALLKF 217

Query: 453 GAQVNMPADSFESPLTLAACGGHVELAALLIERGASLEEVNDEGYTPLMEAAREGHEEMV 512
                +P+ + +S        G V        R   +   N EG T L +A    H  +V
Sbjct: 216 -----VPSATLDSFFQSGKNRGKV--------RKVDMHLANQEGITALHDAVSMNHVSVV 76

Query: 513 ALLLGQG 519
            LLL  G
Sbjct: 75  KLLLKYG 55

 Score = 41.6 bits (96), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 32/109 (29%), Positives = 49/109 (44%), Gaps = 21/109 (19%)
 Frame = -3

Query: 562 TPLMEAAQEGHLELVKYLLAA-GANVHATTATGDTALTYACENGHTDVA----------- 609
           T L+ AA + +L L+K+LL   G ++++    G TAL  AC +GH + A           
Sbjct: 381 TMLIRAAIKNNLSLLKHLLTVPGVDINSQDYAGWTALHEACNHGHLECARALLKFVPSAT 202

Query: 610 -DVLLQAG--------ADLEHESEGGRTPLMKAARAGHVCTVQFLISKG 649
            D   Q+G         D+   ++ G T L  A    HV  V+ L+  G
Sbjct: 201 LDSFFQSGKNRGKVRKVDMHLANQEGITALHDAVSMNHVSVVKLLLKYG 55

 Score = 40.0 bits (92), Expect = 0.012,   Method: Compositional matrix adjust.
 Identities = 38/119 (31%), Positives = 59/119 (49%), Gaps = 21/119 (17%)
 Frame = -3

Query: 289 VEDRGIKGDITPLMAAANGGHVKIVK-LLLAHKADVNAQSSTGNTALTYACAGGYVDVVK 347
           V  +  KG+ T L+ AA   ++ ++K LL     D+N+Q   G TAL  AC  G+++  +
Sbjct: 408 VNKKNHKGE-TMLIRAAIKNNLSLLKHLLTVPGVDINSQDYAGWTALHEACNHGHLECAR 232

Query: 348 VLL------------ESGAS------IEDH--NENGHTPLMEAGSAGHVEVARLLLENG 386
            LL            +SG +      ++ H  N+ G T L +A S  HV V +LLL+ G
Sbjct: 231 ALLKFVPSATLDSFFQSGKNRGKVRKVDMHLANQEGITALHDAVSMNHVSVVKLLLKYG 55

 Score = 35.4 bits (80), Expect = 0.34,   Method: Compositional matrix adjust.
 Identities = 39/157 (24%), Positives = 69/157 (43%), Gaps = 5/157 (3%)
 Frame = -3

Query: 216 TRMRAESTANAGQSDNRSLAEACSEGDVNAVRKLL-IEGRSVNEHTEEGESLLCLACSAG 274
           T + A+            L  A  + +++ ++ LL + G  +N     G + L  AC+ G
Sbjct: 429 TSLTADKVNKKNHKGETMLIRAAIKNNLSLLKHLLTVPGVDINSQDYAGWTALHEACNHG 250

Query: 275 YYELAQVLLAM--HANVEDRGIKGDITPLMAAANGGHVKIVKLLLAHKADVNAQSSTGNT 332
           + E A+ LL     A ++        +   +  N G V+        K D++  +  G T
Sbjct: 249 HLECARALLKFVPSATLD--------SFFQSGKNRGKVR--------KVDMHLANQEGIT 118

Query: 333 ALTYACAGGYVDVVKVLLESGAS--IEDHNENGHTPL 367
           AL  A +  +V VVK+LL+ G S  ++D   +G T +
Sbjct: 117 ALHDAVSMNHVSVVKLLLKYGGSSLLKDKTVSGDTVM 7
>15772
          Length = 1282

 Score = 45.8 bits (107), Expect = 2e-04,   Method: Composition-based stats.
 Identities = 34/122 (27%), Positives = 61/122 (50%), Gaps = 2/122 (1%)
 Frame = -3

Query: 303  AAANGGHVKIVKLLLAHKADVNAQS-STGN-TALTYACAGGYVDVVKVLLESGASIEDHN 360
            AA+ G +  +   + +   DVN +    GN TAL +AC  G+V+ +++LL+ GA      
Sbjct: 1265 AASTGDYDALEDYVKSGIYDVNLKDPDAGNKTALHWACQKGFVECIRLLLDHGAKGTART 1086

Query: 361  ENGHTPLMEAGSAGHVEVARLLLENGAGINTHSNEFKESALTLACYKGHLEMVRFLLEAG 420
            + G TP   A     V   R L      ++  ++++ ++   +A   GH +  R+LL+A 
Sbjct: 1085 DTGWTPAHCAAECNRVTALRALHAALVPVDL-TDKYGDTPRRIATLYGHRDCARYLLQAE 909

Query: 421  AD 422
            A+
Sbjct: 908  AE 903

 Score = 42.7 bits (99), Expect = 0.002,   Method: Composition-based stats.
 Identities = 35/116 (30%), Positives = 47/116 (40%)
 Frame = -3

Query: 1288 AASGGYAEVGRVLLDKGADVNAPPVPSSRDTALTIAADKGHYKFCELLIGKGAHIDVRNK 1347
            A++G Y  +   +     DVN     +   TAL  A  KG  +   LL+  GA    R  
Sbjct: 1262 ASTGDYDALEDYVKSGIYDVNLKDPDAGNKTALHWACQKGFVECIRLLLDHGAKGTARTD 1083

Query: 1348 KGNTPLWLAANGGHLDVVQLLVQATADVDAADNRKITPLMAAFRKGHVKVVRYLVK 1403
             G TP   AA    +  ++ L  A   VD  D    TP   A   GH    RYL++
Sbjct: 1082 TGWTPAHCAAECNRVTALRALHAALVPVDLTDKYGDTPRRIATLYGHRDCARYLLQ 915

 Score = 41.6 bits (96), Expect = 0.005,   Method: Composition-based stats.
 Identities = 40/138 (28%), Positives = 54/138 (39%)
 Frame = -3

Query: 1245 ETNRNTALTLACFQGRTEVVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKG 1304
            +    TAL  AC +G  E + LLLD  A    R  TG TP   AA        R L    
Sbjct: 1187 DAGNKTALHWACQKGFVECIRLLLDHGAKGTARTDTGWTPAHCAAECNRVTALRAL---- 1020

Query: 1305 ADVNAPPVPSSRDTALTIAADKGHYKFCELLIGKGAHIDVRNKKGNTPLWLAANGGHLDV 1364
               +A  VP                            +D+ +K G+TP  +A   GH D 
Sbjct: 1019 ---HAALVP----------------------------VDLTDKYGDTPRRIATLYGHRDC 933

Query: 1365 VQLLVQATADVDAADNRK 1382
             + L+QA A+V  A+ R+
Sbjct: 932  ARYLLQAEAEV--AERRR 885

 Score = 40.0 bits (92), Expect = 0.012,   Method: Composition-based stats.
 Identities = 29/99 (29%), Positives = 46/99 (46%)
 Frame = -3

Query: 398  ESALTLACYKGHLEMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVN 457
            ++AL  AC KG +E +R LL+ GA    +TD   T    A     V   R L  +   V+
Sbjct: 1175 KTALHWACQKGFVECIRLLLDHGAKGTARTDTGWTPAHCAAECNRVTALRALHAALVPVD 996

Query: 458  MPADSFESPLTLAACGGHVELAALLIERGASLEEVNDEG 496
            +     ++P  +A   GH + A  L++  A + E   +G
Sbjct: 995  LTDKYGDTPRRIATLYGHRDCARYLLQAEAEVAERRRKG 879

 Score = 38.5 bits (88), Expect = 0.039,   Method: Composition-based stats.
 Identities = 33/124 (26%), Positives = 54/124 (43%), Gaps = 2/124 (1%)
 Frame = -3

Query: 1119 AATAGHVGVVEILLDNGA-DIEAQS-ERTKDTPLSLACSGGRQEVVELLLARGANKEHRN 1176
            AA+ G    +E  + +G  D+  +  +    T L  AC  G  E + LLL  GA    R 
Sbjct: 1265 AASTGDYDALEDYVKSGIYDVNLKDPDAGNKTALHWACQKGFVECIRLLLDHGAKGTART 1086

Query: 1177 VSDYTPLSLAASGGYVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHTAAVKLLLDM 1236
             + +TP   AA    V  ++ L  A   ++     K G +P  +A + GH    + LL  
Sbjct: 1085 DTGWTPAHCAAECNRVTALRALHAALVPVD--LTDKYGDTPRRIATLYGHRDCARYLLQA 912

Query: 1237 GSDI 1240
             +++
Sbjct: 911  EAEV 900

 Score = 37.7 bits (86), Expect = 0.055,   Method: Composition-based stats.
 Identities = 36/133 (27%), Positives = 56/133 (42%), Gaps = 3/133 (2%)
 Frame = -3

Query: 564  LMEAAQEGHLELVKYLLAAG---ANVHATTATGDTALTYACENGHTDVADVLLQAGADLE 620
            L +AA  G  + ++  + +G    N+    A   TAL +AC+ G  +   +LL  GA   
Sbjct: 1274 LHDAASTGDYDALEDYVKSGIYDVNLKDPDAGNKTALHWACQKGFVECIRLLLDHGAKGT 1095

Query: 621  HESEGGRTPLMKAARAGHVCTVQFLISKGANVNRTTANNDHTVLSLACAGGHLAVVELLL 680
              ++ G TP   AA    V  ++ L +    V+ T    D T   +A   GH      LL
Sbjct: 1094 ARTDTGWTPAHCAAECNRVTALRALHAALVPVDLTDKYGD-TPRRIATLYGHRDCARYLL 918

Query: 681  AHGADPTHRLKDG 693
               A+   R + G
Sbjct: 917  QAEAEVAERRRKG 879

 Score = 37.0 bits (84), Expect = 0.11,   Method: Composition-based stats.
 Identities = 28/100 (28%), Positives = 44/100 (44%)
 Frame = -3

Query: 1076 ESNHDTALTLACAGGHEELVQTLLERGASIEHRDKKGFTPLILAATAGHVGVVEILLDNG 1135
            ++ + TAL  AC  G  E ++ LL+ GA    R   G+TP   AA    V  +  L    
Sbjct: 1187 DAGNKTALHWACQKGFVECIRLLLDHGAKGTARTDTGWTPAHCAAECNRVTALRALHAAL 1008

Query: 1136 ADIEAQSERTKDTPLSLACSGGRQEVVELLLARGANKEHR 1175
              ++  +++  DTP  +A   G ++    LL   A    R
Sbjct: 1007 VPVDL-TDKYGDTPRRIATLYGHRDCARYLLQAEAEVAER 891

 Score = 34.7 bits (78), Expect = 0.54,   Method: Composition-based stats.
 Identities = 31/93 (33%), Positives = 40/93 (43%), Gaps = 4/93 (4%)
 Frame = -3

Query: 538  CCGGFLEVADFLIKAGAD----IELGCSTPLMEAAQEGHLELVKYLLAAGANVHATTATG 593
            C  GF+E    L+  GA      + G  TP   AA+   +  ++ L AA   V  T   G
Sbjct: 1154 CQKGFVECIRLLLDHGAKGTARTDTGW-TPAHCAAECNRVTALRALHAALVPVDLTDKYG 978

Query: 594  DTALTYACENGHTDVADVLLQAGADLEHESEGG 626
            DT    A   GH D A  LLQA A++      G
Sbjct: 977  DTPRRIATLYGHRDCARYLLQAEAEVAERRRKG 879
>15359
          Length = 780

 Score = 43.5 bits (101), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 35/97 (36%), Positives = 53/97 (54%), Gaps = 2/97 (2%)
 Frame = +1

Query: 1285 LMEAASGGYAEVGRVLLDKGADVNAPPVPSSRDTALTIAADKGHYKFCELLIGK-GAHID 1343
            ++ +A+  Y E+ R LL+K A +      ++  TAL  AA  G  +  ++L  K G  I+
Sbjct: 259  MLVSATADYHEMFR-LLNKNARLAKVKDIANGYTALHWAAKFGKPEVVKMLANKIGVEIN 435

Query: 1344 VRNKKGNTPLWLAANGGHLDVVQLLVQA-TADVDAAD 1379
             R+  G TPL LAA  GH D+++LLV    AD +  D
Sbjct: 436  QRSHGGYTPLHLAAIHGHEDIIELLVTGYKADANIRD 546

 Score = 41.2 bits (95), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 25/56 (44%), Positives = 34/56 (60%), Gaps = 1/56 (1%)
 Frame = +1

Query: 1180 YTPLSLAASGGYVNIIKILLNA-GAEINSRTGSKLGISPLMLAAMNGHTAAVKLLL 1234
            YT L  AA  G   ++K+L N  G EIN R  S  G +PL LAA++GH   ++LL+
Sbjct: 352  YTALHWAAKFGKPEVVKMLANKIGVEINQR--SHGGYTPLHLAAIHGHEDIIELLV 513

 Score = 40.4 bits (93), Expect = 0.009,   Method: Compositional matrix adjust.
 Identities = 23/57 (40%), Positives = 32/57 (56%), Gaps = 1/57 (1%)
 Frame = +1

Query: 1077 SNHDTALTLACAGGHEELVQTLLER-GASIEHRDKKGFTPLILAATAGHVGVVEILL 1132
            +N  TAL  A   G  E+V+ L  + G  I  R   G+TPL LAA  GH  ++E+L+
Sbjct: 343  ANGYTALHWAAKFGKPEVVKMLANKIGVEINQRSHGGYTPLHLAAIHGHEDIIELLV 513

 Score = 39.3 bits (90), Expect = 0.021,   Method: Compositional matrix adjust.
 Identities = 31/101 (30%), Positives = 51/101 (50%), Gaps = 4/101 (3%)
 Frame = +1

Query: 1116 LILAATAGHVGVVEILLDNGADIEAQSERTKDTPLSLACSGGRQEVVELLLAR-GANKEH 1174
            ++++ATA +  +  +L  N    + +      T L  A   G+ EVV++L  + G     
Sbjct: 259  MLVSATADYHEMFRLLNKNARLAKVKDIANGYTALHWAAKFGKPEVVKMLANKIGVEINQ 438

Query: 1175 RNVSDYTPLSLAASGGYVNIIKILL---NAGAEINSRTGSK 1212
            R+   YTPL LAA  G+ +II++L+    A A I   +G K
Sbjct: 439  RSHGGYTPLHLAAIHGHEDIIELLVTGYKADANIRDYSGKK 561

 Score = 38.1 bits (87), Expect = 0.048,   Method: Compositional matrix adjust.
 Identities = 34/100 (34%), Positives = 53/100 (53%), Gaps = 4/100 (4%)
 Frame = +1

Query: 428 DEMHTALMEACMDGHVEVARLLLDSG--AQVNMPADSFESPLTLAACGGHVELAALLIER 485
           +E    L+ A  D H E+ RLL  +   A+V   A+ + + L  AA  G  E+  +L  +
Sbjct: 244 EEKEWMLVSATADYH-EMFRLLNKNARLAKVKDIANGY-TALHWAAKFGKPEVVKMLANK 417

Query: 486 -GASLEEVNDEGYTPLMEAAREGHEEMVALLL-GQGANIN 523
            G  + + +  GYTPL  AA  GHE+++ LL+ G  A+ N
Sbjct: 418 IGVEINQRSHGGYTPLHLAAIHGHEDIIELLVTGYKADAN 537
>28113
          Length = 449

 Score = 43.1 bits (100), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 32/88 (36%), Positives = 44/88 (50%)
 Frame = -3

Query: 297 DITPLMAAANGGHVKIVKLLLAHKADVNAQSSTGNTALTYACAGGYVDVVKVLLESGASI 356
           D  PL A+A  G V  V+ LL H    + + S    A+ YA   G  DVV++LL++G S 
Sbjct: 333 DKYPLHASAAQGDVHHVQSLLNHGHHHSKKDSIAWAAIHYASWYGSADVVEILLDAGCSP 154

Query: 357 EDHNENGHTPLMEAGSAGHVEVARLLLE 384
              N    TPL  A   G  +VA  L++
Sbjct: 153 NLTNSELLTPLHIAAKKGFPDVAEHLVQ 70

 Score = 36.6 bits (83), Expect = 0.14,   Method: Compositional matrix adjust.
 Identities = 32/102 (31%), Positives = 51/102 (50%), Gaps = 1/102 (0%)
 Frame = -3

Query: 1108 RDKKGFTPLILAATAGHVGVVEILLDNGADIEAQSERTKDTPLSLACSGGRQEVVELLLA 1167
            RDK    PL  +A  G V  V+ LL++G    ++ +      +  A   G  +VVE+LL 
Sbjct: 336  RDK---YPLHASAAQGDVHHVQSLLNHGHH-HSKKDSIAWAAIHYASWYGSADVVEILLD 169

Query: 1168 RGANKEHRNVSDYTPLSLAASGGYVNIIKILLNAGA-EINSR 1208
             G +    N    TPL +AA  G+ ++ + L+ A A ++N R
Sbjct: 168  AGCSPNLTNSELLTPLHIAAKKGFPDVAEHLVQAEAIDLNLR 43

 Score = 35.0 bits (79), Expect = 0.41,   Method: Compositional matrix adjust.
 Identities = 27/84 (32%), Positives = 37/84 (44%)
 Frame = -3

Query: 1083 LTLACAGGHEELVQTLLERGASIEHRDKKGFTPLILAATAGHVGVVEILLDNGADIEAQS 1142
            L  + A G    VQ+LL  G     +D   +  +  A+  G   VVEILLD G      +
Sbjct: 321  LHASAAQGDVHHVQSLLNHGHHHSKKDSIAWAAIHYASWYGSADVVEILLDAGCSPNLTN 142

Query: 1143 ERTKDTPLSLACSGGRQEVVELLL 1166
                 TPL +A   G  +V E L+
Sbjct: 141  SELL-TPLHIAAKKGFPDVAEHLV 73

 Score = 33.1 bits (74), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 26/95 (27%), Positives = 44/95 (46%), Gaps = 1/95 (1%)
 Frame = -3

Query: 1310 PPVPSSRDTA-LTIAADKGHYKFCELLIGKGAHIDVRNKKGNTPLWLAANGGHLDVVQLL 1368
            P  P  RD   L  +A +G     + L+  G H   ++      +  A+  G  DVV++L
Sbjct: 354  PVEPRWRDKYPLHASAAQGDVHHVQSLLNHGHHHSKKDSIAWAAIHYASWYGSADVVEIL 175

Query: 1369 VQATADVDAADNRKITPLMAAFRKGHVKVVRYLVK 1403
            + A    +  ++  +TPL  A +KG   V  +LV+
Sbjct: 174  LDAGCSPNLTNSELLTPLHIAAKKGFPDVAEHLVQ 70

 Score = 32.7 bits (73), Expect = 2.2,   Method: Compositional matrix adjust.
 Identities = 28/93 (30%), Positives = 45/93 (48%), Gaps = 1/93 (1%)
 Frame = -3

Query: 1217 PLMLAAMNGHTAAVKLLLDMGSDINAQIETNRNTALTLACFQGRTEVVSLLLDRKANVEH 1276
            PL  +A  G    V+ LL+ G   +++ ++    A+  A + G  +VV +LLD   +   
Sbjct: 324  PLHASAAQGDVHHVQSLLNHGHH-HSKKDSIAWAAIHYASWYGSADVVEILLDAGCSPNL 148

Query: 1277 RAKTGLTPLMEAASGGYAEVGRVLLDKGA-DVN 1308
                 LTPL  AA  G+ +V   L+   A D+N
Sbjct: 147  TNSELLTPLHIAAKKGFPDVAEHLVQAEAIDLN 49
>11861
          Length = 586

 Score = 43.1 bits (100), Expect = 0.001,   Method: Composition-based stats.
 Identities = 41/149 (27%), Positives = 66/149 (44%), Gaps = 7/149 (4%)
 Frame = -1

Query: 544 EVADFLIKAGADI----ELGCSTPLMEAA-QEGHLE--LVKYLLAAGANVHATTATGDTA 596
           ++ D  +  GADI    E G  TPL   A ++ H +   VK LL  GA+  AT ++    
Sbjct: 445 DIVDHCLTHGADINKVDEQG-FTPLFRVAYKDVHPDWVAVKELLIRGADASATESSRKPL 269

Query: 597 LTYACENGHTDVADVLLQAGADLEHESEGGRTPLMKAARAGHVCTVQFLISKGANVNRTT 656
           +  A      DV   L+   AD+    + G+TPL     A ++  + F I     +    
Sbjct: 268 VKLAVRKKQWDVVKALILNHADIYRPDKMGQTPLSTLITAANMEMIHFAIQHCPGMAGAV 89

Query: 657 ANNDHTVLSLACAGGHLAVVELLLAHGAD 685
             +  T+L +AC      +++ L+  GAD
Sbjct: 88  DMSGQTILHVACQLQRPDLLQXLIKDGAD 2

 Score = 41.2 bits (95), Expect = 0.005,   Method: Composition-based stats.
 Identities = 30/110 (27%), Positives = 55/110 (50%)
 Frame = -1

Query: 313 VKLLLAHKADVNAQSSTGNTALTYACAGGYVDVVKVLLESGASIEDHNENGHTPLMEAGS 372
           VK LL   AD +A  S+    +  A      DVVK L+ + A I   ++ G TPL    +
Sbjct: 331 VKELLIRGADASATESSRKPLVKLAVRKKQWDVVKALILNHADIYRPDKMGQTPLSTLIT 152

Query: 373 AGHVEVARLLLENGAGINTHSNEFKESALTLACYKGHLEMVRFLLEAGAD 422
           A ++E+    +++  G+    +   ++ L +AC     ++++ L++ GAD
Sbjct: 151 AANMEMIHFAIQHCPGMAGAVDMSGQTILHVACQLQRPDLLQXLIKDGAD 2

 Score = 38.1 bits (87), Expect = 0.047,   Method: Composition-based stats.
 Identities = 40/148 (27%), Positives = 65/148 (43%), Gaps = 6/148 (4%)
 Frame = -1

Query: 1229 AVKLLLDMGSDINAQIETNRNTALTLACFQGRTEVVSLLLDRKANVEHRAKTGLTPLMEA 1288
            A+K LL     +  Q   +R  AL  A  + + ++V   L   A++    + G TPL   
Sbjct: 535  AIKPLLTEKDSMGNQ---HRCIALHEAAKRHQWDIVDHCLTHGADINKVDEQGFTPLFRV 365

Query: 1289 ASGGYAEVG------RVLLDKGADVNAPPVPSSRDTALTIAADKGHYKFCELLIGKGAHI 1342
            A   Y +V       + LL +GAD +A    SSR   + +A  K  +   + LI   A I
Sbjct: 364  A---YKDVHPDWVAVKELLIRGADASA--TESSRKPLVKLAVRKKQWDVVKALILNHADI 200

Query: 1343 DVRNKKGNTPLWLAANGGHLDVVQLLVQ 1370
               +K G TPL       +++++   +Q
Sbjct: 199  YRPDKMGQTPLSTLITAANMEMIHFAIQ 116

 Score = 37.7 bits (86), Expect = 0.066,   Method: Composition-based stats.
 Identities = 25/99 (25%), Positives = 48/99 (48%)
 Frame = -1

Query: 1073 AQTESNHDTALTLACAGGHEELVQTLLERGASIEHRDKKGFTPLILAATAGHVGVVEILL 1132
            + TES+    + LA      ++V+ L+   A I   DK G TPL    TA ++ ++   +
Sbjct: 298  SATESSRKPLVKLAVRKKQWDVVKALILNHADIYRPDKMGQTPLSTLITAANMEMIHFAI 119

Query: 1133 DNGADIEAQSERTKDTPLSLACSGGRQEVVELLLARGAN 1171
             +   +    + +  T L +AC   R ++++ L+  GA+
Sbjct: 118  QHCPGMAGAVDMSGQTILHVACQLQRPDLLQXLIKDGAD 2

 Score = 37.4 bits (85), Expect = 0.076,   Method: Composition-based stats.
 Identities = 40/140 (28%), Positives = 63/140 (45%), Gaps = 9/140 (6%)
 Frame = -1

Query: 1065 IYPAI-----DIDAQTESNHDTALTLACAGGHEELVQTLLERGASIEHRDKKGFTPLILA 1119
            I+PAI     + D+    +   AL  A      ++V   L  GA I   D++GFTPL   
Sbjct: 544  IWPAIKPLLTEKDSMGNQHRCIALHEAAKRHQWDIVDHCLTHGADINKVDEQGFTPLFRV 365

Query: 1120 ATA----GHVGVVEILLDNGADIEAQSERTKDTPLSLACSGGRQEVVELLLARGANKEHR 1175
            A        V V E+L+  GAD  A +E ++   + LA    + +VV+ L+   A+    
Sbjct: 364  AYKDVHPDWVAVKELLI-RGADASA-TESSRKPLVKLAVRKKQWDVVKALILNHADIYRP 191

Query: 1176 NVSDYTPLSLAASGGYVNII 1195
            +    TPLS   +   + +I
Sbjct: 190  DKMGQTPLSTLITAANMEMI 131

 Score = 35.8 bits (81), Expect = 0.25,   Method: Composition-based stats.
 Identities = 29/114 (25%), Positives = 53/114 (46%), Gaps = 1/114 (0%)
 Frame = -1

Query: 242 DVNAVRKLLIEGRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGIKGDITPL 301
           D  AV++LLI G   +      + L+ LA     +++ + L+  HA++  R  K   TPL
Sbjct: 343 DWVAVKELLIRGADASATESSRKPLVKLAVRKKQWDVVKALILNHADIY-RPDKMGQTPL 167

Query: 302 MAAANGGHVKIVKLLLAH-KADVNAQSSTGNTALTYACAGGYVDVVKVLLESGA 354
                  +++++   + H      A   +G T L  AC     D+++ L++ GA
Sbjct: 166 STLITAANMEMIHFAIQHCPGMAGAVDMSGQTILHVACQLQRPDLLQXLIKDGA 5

 Score = 31.2 bits (69), Expect = 5.7,   Method: Composition-based stats.
 Identities = 31/105 (29%), Positives = 47/105 (44%), Gaps = 3/105 (2%)
 Frame = -1

Query: 596 ALTYACENGHTDVADVLLQAGADLEHESEGGRTPLMKAARAG---HVCTVQFLISKGANV 652
           AL  A +    D+ D  L  GAD+    E G TPL + A          V+ L+ +GA+ 
Sbjct: 478 ALHEAAKRHQWDIVDHCLTHGADINKVDEQGFTPLFRVAYKDVHPDWVAVKELLIRGADA 299

Query: 653 NRTTANNDHTVLSLACAGGHLAVVELLLAHGADPTHRLKDGSTML 697
           + T ++    ++ LA       VV+ L+ + AD     K G T L
Sbjct: 298 SATESSR-KPLVKLAVRKKQWDVVKALILNHADIYRPDKMGQTPL 167
>03590
          Length = 1068

 Score = 43.1 bits (100), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 39/138 (28%), Positives = 67/138 (48%), Gaps = 12/138 (8%)
 Frame = +1

Query: 1156 GGRQEV---VELLLARGANKEHRNVSDYTPLSLAASGGYVNIIKILLNAGAEINSRTGSK 1212
            GG +E    + L+L    + E + ++  TPL LAA     + +K+L   GA +++   SK
Sbjct: 358  GGVEEKHPGLALILRYKPDLECQTLNSDTPLVLAARSQSADKVKLLAEMGANVDALIKSK 537

Query: 1213 LG---ISPLMLAAMNGHTAAVKLLLDMGSDINAQIETNRNTALTLACFQGRT------EV 1263
            L    ++P +  AM  +   VKLLL  G+D  A     + T L     + R+      ++
Sbjct: 538  LNGNHVTPCLWMAMQKNLPLVKLLLKYGADPKAVSAYTKET-LMHCLVRDRSAEGDVIQL 714

Query: 1264 VSLLLDRKANVEHRAKTG 1281
            + LL+++  +V  R K G
Sbjct: 715  LKLLVEKGLSVNSRDKRG 768

 Score = 42.7 bits (99), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 32/89 (35%), Positives = 49/89 (55%), Gaps = 4/89 (4%)
 Frame = +1

Query: 602 ENGHTDVADVLLQAGADLEHESEGGRTPLMKAARAGHVCTVQFLISKGANVN---RTTAN 658
           E  H  +A ++L+   DLE ++    TPL+ AAR+     V+ L   GANV+   ++  N
Sbjct: 367 EEKHPGLA-LILRYKPDLECQTLNSDTPLVLAARSQSADKVKLLAEMGANVDALIKSKLN 543

Query: 659 NDHTVLSLACA-GGHLAVVELLLAHGADP 686
            +H    L  A   +L +V+LLL +GADP
Sbjct: 544 GNHVTPCLWMAMQKNLPLVKLLLKYGADP 630

 Score = 39.7 bits (91), Expect = 0.016,   Method: Compositional matrix adjust.
 Identities = 38/135 (28%), Positives = 64/135 (47%), Gaps = 15/135 (11%)
 Frame = +1

Query: 1089 GGHEEL---VQTLLERGASIEHRDKKGFTPLILAATAGHVGVVEILLDNGADIEAQSERT 1145
            GG EE    +  +L     +E +     TPL+LAA +     V++L + GA+++A  +  
Sbjct: 358  GGVEEKHPGLALILRYKPDLECQTLNSDTPLVLAARSQSADKVKLLAEMGANVDALIKSK 537

Query: 1146 KD----TPLSLACSGGRQEVVELLLARGANKEHRNVSDYTPLSL--------AASGGYVN 1193
             +    TP           +V+LLL  GA+   + VS YT  +L        +A G  + 
Sbjct: 538  LNGNHVTPCLWMAMQKNLPLVKLLLKYGADP--KAVSAYTKETLMHCLVRDRSAEGDVIQ 711

Query: 1194 IIKILLNAGAEINSR 1208
            ++K+L+  G  +NSR
Sbjct: 712  LLKLLVEKGLSVNSR 756

 Score = 38.1 bits (87), Expect = 0.048,   Method: Compositional matrix adjust.
 Identities = 32/104 (30%), Positives = 55/104 (52%), Gaps = 10/104 (9%)
 Frame = +1

Query: 1216 SPLMLAAMNGHTAAVKLLLDMGSDINAQIETNRNTALTLACF----QGRTEVVSLLL--- 1268
            +PL+LAA +     VKLL +MG++++A I++  N      C     Q    +V LLL   
Sbjct: 442  TPLVLAARSQSADKVKLLAEMGANVDALIKSKLNGNHVTPCLWMAMQKNLPLVKLLLKYG 621

Query: 1269 -DRKANVEHRAKTGLTPLM--EAASGGYAEVGRVLLDKGADVNA 1309
             D KA   +  +T +  L+   +A G   ++ ++L++KG  VN+
Sbjct: 622  ADPKAVSAYTKETLMHCLVRDRSAEGDVIQLLKLLVEKGLSVNS 753

 Score = 35.8 bits (81), Expect = 0.26,   Method: Compositional matrix adjust.
 Identities = 31/108 (28%), Positives = 51/108 (47%), Gaps = 11/108 (10%)
 Frame = +1

Query: 267 LCLACSAGYYELAQVLLAMHANVEDRGIKGD-----ITPLMAAANGGHVKIVKLLLAHKA 321
           L LA  +   +  ++L  M ANV D  IK       +TP +  A   ++ +VKLLL + A
Sbjct: 448 LVLAARSQSADKVKLLAEMGANV-DALIKSKLNGNHVTPCLWMAMQKNLPLVKLLLKYGA 624

Query: 322 DVNAQSSTGNTALTYACA------GGYVDVVKVLLESGASIEDHNENG 363
           D  A S+     L +         G  + ++K+L+E G S+   ++ G
Sbjct: 625 DPKAVSAYTKETLMHCLVRDRSAEGDVIQLLKLLVEKGLSVNSRDKRG 768
>21751
          Length = 643

 Score = 35.4 bits (80), Expect(2) = 0.004,   Method: Composition-based stats.
 Identities = 26/66 (39%), Positives = 38/66 (57%), Gaps = 4/66 (6%)
 Frame = +1

Query: 357 EDHNENGHTPLMEAGSAGHVEVARLLLENGAGIN--THSNEFKE--SALTLACYKGHLEM 412
           E H   G + +ME   A   E+A+ L+  GA  N  T  + F++  S L +AC+KG+L  
Sbjct: 277 ERHTPVGLSLIMEDPIA--TEIAKRLIVAGASANQRTRISFFQKTYSPLHIACFKGNLGF 450

Query: 413 VRFLLE 418
           VRFL+E
Sbjct: 451 VRFLVE 468

 Score = 25.4 bits (54), Expect(2) = 0.004,   Method: Composition-based stats.
 Identities = 18/63 (28%), Positives = 32/63 (50%), Gaps = 1/63 (1%)
 Frame = +3

Query: 299 TPLMAAANGGHVKIVKLLLAHKADVNAQ-SSTGNTALTYACAGGYVDVVKVLLESGASIE 357
           +PL  A    +V + +LLL H  DVN   + +  + +  A     +D++ +L+E GA + 
Sbjct: 84  SPLHVAILRKNVHLGRLLLEHGEDVNQTFNDSLESPIHQAVRNLDLDMINLLIEFGADLN 263

Query: 358 DHN 360
             N
Sbjct: 264 RPN 272

 Score = 35.4 bits (80), Expect = 0.28,   Method: Composition-based stats.
 Identities = 29/88 (32%), Positives = 41/88 (46%), Gaps = 9/88 (10%)
 Frame = +3

Query: 415 FLLEAGAD--------QEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMP-ADSFES 465
            L++ GAD         + K     + L  A +  +V + RLLL+ G  VN    DS ES
Sbjct: 9   LLIQYGADVHQLRTVSLDDKVFTSQSPLHVAILRKNVHLGRLLLEHGEDVNQTFNDSLES 188

Query: 466 PLTLAACGGHVELAALLIERGASLEEVN 493
           P+  A     +++  LLIE GA L   N
Sbjct: 189 PIHQAVRNLDLDMINLLIEFGADLNRPN 272
>17893
          Length = 453

 Score = 41.6 bits (96), Expect = 0.005,   Method: Composition-based stats.
 Identities = 22/48 (45%), Positives = 30/48 (62%)
 Frame = -3

Query: 343 VDVVKVLLESGASIEDHNENGHTPLMEAGSAGHVEVARLLLENGAGIN 390
           +D V  LL++GASI   +  G T L EA  A HV+V R LL++G  I+
Sbjct: 181 LDFVDSLLKNGASINIMDRTGQTLLHEAARAWHVDVTRWLLDHGINID 38

 Score = 39.7 bits (91), Expect = 0.015,   Method: Compositional matrix adjust.
 Identities = 22/47 (46%), Positives = 29/47 (61%)
 Frame = -3

Query: 1093 ELVQTLLERGASIEHRDKKGFTPLILAATAGHVGVVEILLDNGADIE 1139
            + V +LL+ GASI   D+ G T L  AA A HV V   LLD+G +I+
Sbjct: 178  DFVDSLLKNGASINIMDRTGQTLLHEAARAWHVDVTRWLLDHGINID 38

 Score = 35.4 bits (80), Expect = 0.34,   Method: Composition-based stats.
 Identities = 21/59 (35%), Positives = 29/59 (49%)
 Frame = -3

Query: 572 HLELVKYLLAAGANVHATTATGDTALTYACENGHTDVADVLLQAGADLEHESEGGRTPL 630
           +L+ V  LL  GA+++    TG T L  A    H DV   LL  G +++     GRT L
Sbjct: 184 NLDFVDSLLKNGASINIMDRTGQTLLHEAARAWHVDVTRWLLDHGINIDQPDYYGRTAL 8

 Score = 33.1 bits (74), Expect = 1.7,   Method: Composition-based stats.
 Identities = 21/58 (36%), Positives = 31/58 (53%), Gaps = 3/58 (5%)
 Frame = -3

Query: 543 LEVADFLIKAGADIEL---GCSTPLMEAAQEGHLELVKYLLAAGANVHATTATGDTAL 597
           L+  D L+K GA I +      T L EAA+  H+++ ++LL  G N+      G TAL
Sbjct: 181 LDFVDSLLKNGASINIMDRTGQTLLHEAARAWHVDVTRWLLDHGINIDQPDYYGRTAL 8

 Score = 32.7 bits (73), Expect = 2.0,   Method: Composition-based stats.
 Identities = 25/106 (23%), Positives = 48/106 (45%)
 Frame = -3

Query: 1205 INSRTGSKLGISPLMLAAMNGHTAAVKLLLDMGSDINAQIETNRNTALTLACFQGRTEVV 1264
            I  ++ ++L +S      ++ + A ++  +DM    + + + N              + V
Sbjct: 298  IRRQSSTRLNVS----MVIDSNRALIQHFVDMADSPHEEAKIN-------------LDFV 170

Query: 1265 SLLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADVNAP 1310
              LL   A++    +TG T L EAA   + +V R LLD G +++ P
Sbjct: 169  DSLLKNGASINIMDRTGQTLLHEAARAWHVDVTRWLLDHGINIDQP 32

 Score = 32.0 bits (71), Expect = 3.3,   Method: Composition-based stats.
 Identities = 17/42 (40%), Positives = 25/42 (59%)
 Frame = -3

Query: 482 LIERGASLEEVNDEGYTPLMEAAREGHEEMVALLLGQGANIN 523
           L++ GAS+  ++  G T L EAAR  H ++   LL  G NI+
Sbjct: 163 LLKNGASINIMDRTGQTLLHEAARAWHVDVTRWLLDHGINID 38

 Score = 32.0 bits (71), Expect = 3.7,   Method: Composition-based stats.
 Identities = 20/53 (37%), Positives = 26/53 (49%)
 Frame = -3

Query: 407 KGHLEMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMP 459
           K +L+ V  LL+ GA          T L EA    HV+V R LLD G  ++ P
Sbjct: 190 KINLDFVDSLLKNGASINIMDRTGQTLLHEAARAWHVDVTRWLLDHGINIDQP 32

 Score = 30.8 bits (68), Expect = 6.7,   Method: Composition-based stats.
 Identities = 18/48 (37%), Positives = 27/48 (56%)
 Frame = -3

Query: 672 HLAVVELLLAHGADPTHRLKDGSTMLIEAAKGGHTSVVCYLLDYPNNL 719
           +L  V+ LL +GA      + G T+L EAA+  H  V  +LLD+  N+
Sbjct: 184 NLDFVDSLLKNGASINIMDRTGQTLLHEAARAWHVDVTRWLLDHGINI 41
>09451
          Length = 1994

 Score = 41.2 bits (95), Expect = 0.005,   Method: Composition-based stats.
 Identities = 17/59 (28%), Positives = 32/59 (54%)
 Frame = -2

Query: 1735 RVIGRGGCNINAIRECTGAHIDIDKQKDKTGDRIITIRGGTESTRQATQLINALIKDPD 1793
            ++IGRGG  I  ++  +G  I + ++ D  G R + + G  +    A  +IN+L+ + D
Sbjct: 1852 KIIGRGGSKIRDLQTGSGCRIKVSREDDGNGKRRVELTGSEDQIDAARDMINSLLAEDD 1676

 Score = 33.5 bits (75), Expect = 1.2,   Method: Composition-based stats.
 Identities = 15/60 (25%), Positives = 30/60 (50%)
 Frame = -2

Query: 1730 STVISRVIGRGGCNINAIRECTGAHIDIDKQKDKTGDRIITIRGGTESTRQATQLINALI 1789
            S  + R+IG+GG  I  ++E TG  I++ +   + G   + + G   +   A + I  ++
Sbjct: 1549 SDFVGRIIGKGGSRIRELQEDTGCRINVSRDPGRDGQTEVELIGSHSAISNAKRAIADIV 1370
>28491
          Length = 394

 Score = 40.8 bits (94), Expect = 0.008,   Method: Composition-based stats.
 Identities = 26/57 (45%), Positives = 35/57 (61%), Gaps = 5/57 (8%)
 Frame = +3

Query: 299 TPLMAA---ANGGH-VKIVKLLLAHKADVNAQSSTGNTALTYACA-GGYVDVVKVLL 350
           TPL+ A   A G H + ++KLLL   +DVNAQ   G T+L +  A GG VD V+ L+
Sbjct: 204 TPLLYASRYAKGDHGIYLIKLLLRQGSDVNAQDDAGMTSLMHVIAEGGSVDAVRPLI 374
>04763
          Length = 1073

 Score = 40.0 bits (92), Expect = 0.011,   Method: Composition-based stats.
 Identities = 21/62 (33%), Positives = 33/62 (53%)
 Frame = -3

Query: 1729 PSTVISRVIGRGGCNINAIRECTGAHIDIDKQKDKTGDRIITIRGGTESTRQATQLINAL 1788
            P  +   +IG+GG  I  IR  +GA I ID+    + +RII+I G  E  + A  ++   
Sbjct: 762  PKDMAGAIIGKGGARITEIRRRSGAQIVIDEALPGSNERIISIIGSQEQIQNAQYMLQLS 583

Query: 1789 IK 1790
            +K
Sbjct: 582  VK 577
>02351
          Length = 939

 Score = 40.0 bits (92), Expect = 0.012,   Method: Compositional matrix adjust.
 Identities = 22/66 (33%), Positives = 34/66 (51%)
 Frame = +3

Query: 1306 DVNAPPVPSSRDTALTIAADKGHYKFCELLIGKGAHIDVRNKKGNTPLWLAANGGHLDVV 1365
            D+N+P       TAL IAA  G+  + +LL+   A++ V + +G   LW A   G ++  
Sbjct: 438  DINSPYGKDDGRTALHIAAALGNVVYVQLLLWYCANVKVVDHEGRNALWYARTSGSVECT 617

Query: 1366 QLLVQA 1371
             LL  A
Sbjct: 618  DLLAAA 635
>33144
          Length = 272

 Score = 38.5 bits (88), Expect = 0.033,   Method: Compositional matrix adjust.
 Identities = 24/74 (32%), Positives = 35/74 (47%)
 Frame = +3

Query: 1113 FTPLILAATAGHVGVVEILLDNGADIEAQSERTKDTPLSLACSGGRQEVVELLLARGANK 1172
            + PL LAA  G   +  +L+  G       ++ K TPL  A       +++LLL R AN 
Sbjct: 15   WAPLHLAAMNGRTAIAGVLVKKGEVAVNVVDKHKRTPLHYAVQTCELTIIDLLLGRDANP 194

Query: 1173 EHRNVSDYTPLSLA 1186
              ++V   TP  LA
Sbjct: 195  NIQDVDGNTPTHLA 236

 Score = 35.4 bits (80), Expect = 0.30,   Method: Compositional matrix adjust.
 Identities = 24/69 (34%), Positives = 34/69 (49%)
 Frame = +3

Query: 1216 SPLMLAAMNGHTAAVKLLLDMGSDINAQIETNRNTALTLACFQGRTEVVSLLLDRKANVE 1275
            +PL LAAMNG TA   +L+  G      ++ ++ T L  A       ++ LLL R AN  
Sbjct: 18   APLHLAAMNGRTAIAGVLVKKGEVAVNVVDKHKRTPLHYAVQTCELTIIDLLLGRDANPN 197

Query: 1276 HRAKTGLTP 1284
             +   G TP
Sbjct: 198  IQDVDGNTP 224

 Score = 35.0 bits (79), Expect = 0.43,   Method: Compositional matrix adjust.
 Identities = 21/60 (35%), Positives = 34/60 (56%), Gaps = 1/60 (1%)
 Frame = +3

Query: 465 SPLTLAACGGHVELAALLIERG-ASLEEVNDEGYTPLMEAAREGHEEMVALLLGQGANIN 523
           +PL LAA  G   +A +L+++G  ++  V+    TPL  A +     ++ LLLG+ AN N
Sbjct: 18  APLHLAAMNGRTAIAGVLVKKGEVAVNVVDKHKRTPLHYAVQTCELTIIDLLLGRDANPN 197
>35952
          Length = 1624

 Score = 38.5 bits (88), Expect = 0.037,   Method: Compositional matrix adjust.
 Identities = 20/47 (42%), Positives = 28/47 (59%)
 Frame = -1

Query: 315 LLLAHKADVNAQSSTGNTALTYACAGGYVDVVKVLLESGASIEDHNE 361
           LL+   ADVNA+   GNT L  AC  G + +V +L+ +GA  +  NE
Sbjct: 916 LLMEANADVNARCFDGNTPLHVACCRGLIGMVALLMTAGALTDVENE 776
>30217
          Length = 412

 Score = 38.5 bits (88), Expect = 0.040,   Method: Compositional matrix adjust.
 Identities = 27/71 (38%), Positives = 35/71 (49%), Gaps = 3/71 (4%)
 Frame = -3

Query: 1141 QSERTKDTPLSLACSGGRQEVVELLLARGANKEHRNVSD---YTPLSLAASGGYVNIIKI 1197
            Q     DTPL LAC  G  +VV  L+    +    N+ +    TPL LAA      I+++
Sbjct: 221  QQNDDGDTPLHLACISGYVDVVAALIRMAPHPCLLNIQNDVAQTPLHLAALTAQPTILRM 42

Query: 1198 LLNAGAEINSR 1208
            LL AGAE   R
Sbjct: 41   LLLAGAEPTVR 9

 Score = 38.1 bits (87), Expect = 0.042,   Method: Compositional matrix adjust.
 Identities = 23/65 (35%), Positives = 30/65 (46%), Gaps = 3/65 (4%)
 Frame = -3

Query: 326 QSSTGNTALTYACAGGYVDVVKVLLESG---ASIEDHNENGHTPLMEAGSAGHVEVARLL 382
           Q+  G+T L  AC  GYVDVV  L+        +   N+   TPL  A       + R+L
Sbjct: 218 QNDDGDTPLHLACISGYVDVVAALIRMAPHPCLLNIQNDVAQTPLHLAALTAQPTILRML 39

Query: 383 LENGA 387
           L  GA
Sbjct: 38  LLAGA 24

 Score = 31.2 bits (69), Expect = 5.4,   Method: Compositional matrix adjust.
 Identities = 19/62 (30%), Positives = 34/62 (54%), Gaps = 2/62 (3%)
 Frame = -3

Query: 258 EHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGIKGDI--TPLMAAANGGHVKIVKL 315
           +  ++G++ L LAC +GY ++   L+ M  +     I+ D+  TPL  AA      I+++
Sbjct: 221 QQNDDGDTPLHLACISGYVDVVAALIRMAPHPCLLNIQNDVAQTPLHLAALTAQPTILRM 42

Query: 316 LL 317
           LL
Sbjct: 41  LL 36
>27376
          Length = 384

 Score = 38.5 bits (88), Expect = 0.041,   Method: Compositional matrix adjust.
 Identities = 20/58 (34%), Positives = 32/58 (55%), Gaps = 1/58 (1%)
 Frame = -2

Query: 1729 PSTVISRVIGRGGCNINAIRECTGAHIDIDKQ-KDKTGDRIITIRGGTESTRQATQLI 1785
            PS     VIG+GG  I  I+  +GAH+++D+       +++  IRG  +  + A QLI
Sbjct: 218  PSDKCGLVIGKGGETIRDIKSQSGAHVELDRNPPPNMQEKLFNIRGTPQQIQHAIQLI 45
>36879
          Length = 583

 Score = 36.6 bits (83), Expect = 0.13,   Method: Composition-based stats.
 Identities = 17/36 (47%), Positives = 22/36 (61%)
 Frame = -3

Query: 583 GANVHATTATGDTALTYACENGHTDVADVLLQAGAD 618
           G N+HA    G+T L  A +NG   V + LL+AGAD
Sbjct: 494 GINIHAIDDVGETPLMLAAKNGQDYVCERLLEAGAD 387

 Score = 31.6 bits (70), Expect = 4.8,   Method: Composition-based stats.
 Identities = 18/50 (36%), Positives = 28/50 (56%), Gaps = 1/50 (2%)
 Frame = -3

Query: 1191 YVNI-IKILLNAGAEINSRTGSKLGISPLMLAAMNGHTAAVKLLLDMGSD 1239
            ++N+ + +LL     IN      +G +PLMLAA NG     + LL+ G+D
Sbjct: 536  FINMYVDLLLMDCEGINIHAIDDVGETPLMLAAKNGQDYVCERLLEAGAD 387
>05396
          Length = 1865

 Score = 36.6 bits (83), Expect = 0.15,   Method: Composition-based stats.
 Identities = 28/90 (31%), Positives = 46/90 (51%), Gaps = 1/90 (1%)
 Frame = +3

Query: 1215 ISPLMLAAMNGHTAAVKLLLDMGSDINAQIETNRNTALTLACFQGRTEVVSLLLDR-KAN 1273
            I  L+ +A NG   A++     G D+ +Q + +  TAL +A  +G+ +VV  LLDR K +
Sbjct: 1287 IVDLLFSAYNGDVTAIRRCALSGMDM-SQPDYDGRTALHVASAEGQLQVVEFLLDRCKCS 1463

Query: 1274 VEHRAKTGLTPLMEAASGGYAEVGRVLLDK 1303
                 + G TPL +A      E   +L ++
Sbjct: 1464 PFLVDRWGFTPLDDAVRFEKHEAAELLKER 1553

 Score = 32.0 bits (71), Expect = 3.5,   Method: Composition-based stats.
 Identities = 26/95 (27%), Positives = 38/95 (40%)
 Frame = +3

Query: 1074 QTESNHDTALTLACAGGHEELVQTLLERGASIEHRDKKGFTPLILAATAGHVGVVEILLD 1133
            + ++N    L  +   G    ++     G  +   D  G T L +A+  G + VVE LLD
Sbjct: 1269 ELQANRIVDLLFSAYNGDVTAIRRCALSGMDMSQPDYDGRTALHVASAEGQLQVVEFLLD 1448

Query: 1134 NGADIEAQSERTKDTPLSLACSGGRQEVVELLLAR 1168
                     +R   TPL  A    + E  ELL  R
Sbjct: 1449 RCKCSPFLVDRWGFTPLDDAVRFEKHEAAELLKER 1553
>27067
          Length = 409

 Score = 36.2 bits (82), Expect = 0.17,   Method: Compositional matrix adjust.
 Identities = 28/86 (32%), Positives = 35/86 (40%), Gaps = 7/86 (8%)
 Frame = +1

Query: 478 LAALLIERGASLEEVNDEGYTPLMEAAREGHEEMVALLLGQGANI-NXXXXXXXXXXXXX 536
           L  LL   G     VN    TP+MEAA  G  E + +LL  G N                
Sbjct: 73  LRYLLTVPGLECNAVNASQKTPVMEAASRGRIECLTMLLDHGCNTEGENIRGKTAMHHCL 252

Query: 537 XCCGGFLEV------ADFLIKAGADI 556
             CGGF+E+       D + KAG +I
Sbjct: 253 LSCGGFVEIEDMVTCMDLVYKAGGNI 330

 Score = 34.7 bits (78), Expect = 0.50,   Method: Compositional matrix adjust.
 Identities = 23/78 (29%), Positives = 38/78 (48%), Gaps = 9/78 (11%)
 Frame = +1

Query: 562 TPLMEAAQEGHLELVKYLLAAGANVHATTATGDTALTY---ACENGHTDV------ADVL 612
           TP+MEAA  G +E +  LL  G N       G TA+ +   +C  G  ++       D++
Sbjct: 133 TPVMEAASRGRIECLTMLLDHGCNTEGENIRGKTAMHHCLLSC-GGFVEIEDMVTCMDLV 309

Query: 613 LQAGADLEHESEGGRTPL 630
            +AG ++  +   G +PL
Sbjct: 310 YKAGGNINAQDWFGTSPL 363

 Score = 34.3 bits (77), Expect = 0.74,   Method: Compositional matrix adjust.
 Identities = 42/151 (27%), Positives = 62/151 (41%), Gaps = 1/151 (0%)
 Frame = +1

Query: 321 ADVNAQSSTGNTALTYACAGGYVDVVKVLLES-GASIEDHNENGHTPLMEAGSAGHVEVA 379
           AD+N++   G++A+  A      D+++ LL   G      N +  TP+MEA S G +E  
Sbjct: 1   ADINSKFK-GSSAVHEAIKVNNTDILRYLLTVPGLECNAVNASQKTPVMEAASRGRIECL 177

Query: 380 RLLLENGAGINTHSNEFKESALTLACYKGHLEMVRFLLEAGADQEHKTDEMHTALMEACM 439
            +LL++G   NT               +G   M   LL  G   E +        M  CM
Sbjct: 178 TMLLDHGC--NTEGENI----------RGKTAMHHCLLSCGGFVEIED-------MVTCM 300

Query: 440 DGHVEVARLLLDSGAQVNMPADSFESPLTLA 470
           D       L+  +G  +N       SPL LA
Sbjct: 301 D-------LVYKAGGNINAQDWFGTSPLHLA 372

 Score = 32.0 bits (71), Expect = 3.0,   Method: Compositional matrix adjust.
 Identities = 25/83 (30%), Positives = 43/83 (51%), Gaps = 8/83 (9%)
 Frame = +1

Query: 1114 TPLILAATAGHVGVVEILLDNGADIEAQSERTKDT--PLSLACSGGRQEV------VELL 1165
            TP++ AA+ G +  + +LLD+G + E ++ R K       L+C GG  E+      ++L+
Sbjct: 133  TPVMEAASRGRIECLTMLLDHGCNTEGENIRGKTAMHHCLLSC-GGFVEIEDMVTCMDLV 309

Query: 1166 LARGANKEHRNVSDYTPLSLAAS 1188
               G N   ++    +PL LA S
Sbjct: 310  YKAGGNINAQDWFGTSPLHLAIS 378
>32680
          Length = 444

 Score = 36.2 bits (82), Expect = 0.20,   Method: Compositional matrix adjust.
 Identities = 20/58 (34%), Positives = 30/58 (51%), Gaps = 1/58 (1%)
 Frame = +3

Query: 1729 PSTVISRVIGRGGCNINAIRECTGAHIDIDKQ-KDKTGDRIITIRGGTESTRQATQLI 1785
            PS     VIG+GG  I  I   +GAH+++D+       ++   IRG  +  + A QLI
Sbjct: 96   PSDKCGLVIGKGGETIRDINRQSGAHVELDRNPPPNMAEKFFNIRGNPQQIQHAIQLI 269
>18216
          Length = 472

 Score = 36.2 bits (82), Expect = 0.20,   Method: Composition-based stats.
 Identities = 19/50 (38%), Positives = 29/50 (58%)
 Frame = +2

Query: 1332 CELLIGKGAHIDVRNKKGNTPLWLAANGGHLDVVQLLVQATADVDAADNR 1381
            CE ++ KG H++  +  G T    AA  GHL VVQ L++A AD+   + +
Sbjct: 254  CEGVLDKGVHVNAVDPFGWTAAMSAAFEGHLAVVQTLLEAGADLSVINRQ 403

 Score = 35.4 bits (80), Expect = 0.28,   Method: Composition-based stats.
 Identities = 36/141 (25%), Positives = 65/141 (46%), Gaps = 4/141 (2%)
 Frame = +2

Query: 286 HANVEDRGIKGDIT-PLMAAANGGHVKIVKLLLAHKADVNAQSSTGNTALTYACAGGYVD 344
            + VE  G++ D+T PL+            ++L  K  V+  S++G+ +++     G   
Sbjct: 8   QSKVEMTGVRKDVTFPLI------------IMLR*KVTVDKASASGDNSVSSCATKGRKK 151

Query: 345 VVKVLLES---GASIEDHNENGHTPLMEAGSAGHVEVARLLLENGAGINTHSNEFKESAL 401
             +V++        + DH +     L +    G  E    +L+ G  +N   + F  +A 
Sbjct: 152 QEQVIVAEQRLSQRLVDHRQWELLRLAQIXGQGGCEG---VLDKGVHVNA-VDPFGWTAA 319

Query: 402 TLACYKGHLEMVRFLLEAGAD 422
             A ++GHL +V+ LLEAGAD
Sbjct: 320 MSAAFEGHLAVVQTLLEAGAD 382

 Score = 34.7 bits (78), Expect = 0.51,   Method: Composition-based stats.
 Identities = 16/43 (37%), Positives = 27/43 (62%)
 Frame = +2

Query: 1096 QTLLERGASIEHRDKKGFTPLILAATAGHVGVVEILLDNGADI 1138
            + +L++G  +   D  G+T  + AA  GH+ VV+ LL+ GAD+
Sbjct: 257  EGVLDKGVHVNAVDPFGWTAAMSAAFEGHLAVVQTLLEAGADL 385

 Score = 32.7 bits (73), Expect = 2.0,   Method: Composition-based stats.
 Identities = 20/49 (40%), Positives = 25/49 (51%)
 Frame = +2

Query: 579 LLAAGANVHATTATGDTALTYACENGHTDVADVLLQAGADLEHESEGGR 627
           +L  G +V+A    G TA   A   GH  V   LL+AGADL   +  GR
Sbjct: 263 VLDKGVHVNAVDPFGWTAAMSAAFEGHLAVVQTLLEAGADLSVINRQGR 409

 Score = 31.6 bits (70), Expect = 4.6,   Method: Composition-based stats.
 Identities = 15/42 (35%), Positives = 26/42 (61%)
 Frame = +2

Query: 482 LIERGASLEEVNDEGYTPLMEAAREGHEEMVALLLGQGANIN 523
           ++++G  +  V+  G+T  M AA EGH  +V  LL  GA+++
Sbjct: 263 VLDKGVHVNAVDPFGWTAAMSAAFEGHLAVVQTLLEAGADLS 388
>08755
          Length = 885

 Score = 35.8 bits (81), Expect = 0.21,   Method: Compositional matrix adjust.
 Identities = 22/50 (44%), Positives = 32/50 (64%), Gaps = 1/50 (2%)
 Frame = +3

Query: 1160 EVVELLLARGANKEHR-NVSDYTPLSLAASGGYVNIIKILLNAGAEINSR 1208
            EV+ +LLA GAN + + + S  TPL LAAS      ++IL+ AG+ I+ R
Sbjct: 690  EVISVLLAHGANPDVKVDGSGVTPLMLAASMTKTAALQILIGAGSSIDCR 839

 Score = 32.3 bits (72), Expect = 2.4,   Method: Compositional matrix adjust.
 Identities = 19/50 (38%), Positives = 31/50 (62%)
 Frame = +3

Query: 1194 IIKILLNAGAEINSRTGSKLGISPLMLAAMNGHTAAVKLLLDMGSDINAQ 1243
            +I +LL  GA  + +     G++PLMLAA    TAA+++L+  GS I+ +
Sbjct: 693  VISVLLAHGANPDVKVDGS-GVTPLMLAASMTKTAALQILIGAGSSIDCR 839

 Score = 32.0 bits (71), Expect = 3.1,   Method: Compositional matrix adjust.
 Identities = 17/52 (32%), Positives = 31/52 (59%), Gaps = 1/52 (1%)
 Frame = +3

Query: 1093 ELVQTLLERGASIEHR-DKKGFTPLILAATAGHVGVVEILLDNGADIEAQSE 1143
            E++  LL  GA+ + + D  G TPL+LAA+      ++IL+  G+ I+ ++ 
Sbjct: 690  EVISVLLAHGANPDVKVDGSGVTPLMLAASMTKTAALQILIGAGSSIDCRNN 845

 Score = 30.8 bits (68), Expect = 6.8,   Method: Compositional matrix adjust.
 Identities = 19/59 (32%), Positives = 32/59 (54%), Gaps = 1/59 (1%)
 Frame = +3

Query: 1333 ELLIGKGAHIDVR-NKKGNTPLWLAANGGHLDVVQLLVQATADVDAADNRKITPLMAAF 1390
             +L+  GA+ DV+ +  G TPL LAA+      +Q+L+ A + +D  +N  +  L   F
Sbjct: 699  SVLLAHGANPDVKVDGSGVTPLMLAASMTKTAALQILIGAGSSIDCRNNAGMCALHHCF 875
>20121
          Length = 454

 Score = 34.3 bits (77), Expect = 0.68,   Method: Composition-based stats.
 Identities = 20/71 (28%), Positives = 36/71 (50%)
 Frame = -1

Query: 314 KLLLAHKADVNAQSSTGNTALTYACAGGYVDVVKVLLESGASIEDHNENGHTPLMEAGSA 373
           +LL   + D+  +   G TAL  + + G+++  +VLL  GA     N    + L E   +
Sbjct: 298 RLLGLKEHDIETKDPRGRTALHLSVSLGHLESTRVLLRHGAEAGTENNGCWSVLHEGVCS 119

Query: 374 GHVEVARLLLE 384
           G  E+ +L+L+
Sbjct: 118 GDPELVQLILQ 86

 Score = 33.9 bits (76), Expect = 0.88,   Method: Composition-based stats.
 Identities = 24/74 (32%), Positives = 33/74 (44%)
 Frame = -1

Query: 411 EMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLA 470
           E+ R L     D E K     TAL  +   GH+E  R+LL  GA+     +   S L   
Sbjct: 307 ELDRLLGLKEHDIETKDPRGRTALHLSVSLGHLESTRVLLRHGAEAGTENNGCWSVLHEG 128

Query: 471 ACGGHVELAALLIE 484
            C G  EL  L+++
Sbjct: 127 VCSGDPELVQLILQ 86
>20988
          Length = 530

 Score = 33.5 bits (75), Expect = 1.0,   Method: Compositional matrix adjust.
 Identities = 18/50 (36%), Positives = 25/50 (50%)
 Frame = -3

Query: 636 AGHVCTVQFLISKGANVNRTTANNDHTVLSLACAGGHLAVVELLLAHGAD 685
            G VC+ + L      V     N D    +   A GH A+V++LL+HGAD
Sbjct: 192 CGQVCSARGL*LGRCGVXAWDMNEDTAAFTTRAAPGHWAIVDMLLSHGAD 43

 Score = 32.0 bits (71), Expect = 3.2,   Method: Compositional matrix adjust.
 Identities = 12/26 (46%), Positives = 17/26 (65%)
 Frame = -1

Query: 434 LMEACMDGHVEVARLLLDSGAQVNMP 459
           +  AC+ GHV+V R ++D G  VN P
Sbjct: 278 MFGACITGHVDVIRKVVDRGVDVNAP 201
>09541
          Length = 2010

 Score = 33.1 bits (74), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 16/61 (26%), Positives = 30/61 (49%)
 Frame = -1

Query: 1729 PSTVISRVIGRGGCNINAIRECTGAHIDIDKQKDKTGDRIITIRGGTESTRQATQLINAL 1788
            P   +  VIG+GG  I  I+  +GA +       ++ DR+  + G  +  + A  +I+ L
Sbjct: 225  PRQAVGLVIGKGGEMIKKIQNESGAKVQFKPDDGQSEDRLCGVTGSPDKVQNAISMIHEL 46

Query: 1789 I 1789
            +
Sbjct: 45   L 43
>35959
          Length = 383

 Score = 32.3 bits (72), Expect = 2.9,   Method: Compositional matrix adjust.
 Identities = 14/34 (41%), Positives = 21/34 (61%)
 Frame = -3

Query: 1100 ERGASIEHRDKKGFTPLILAATAGHVGVVEILLD 1133
            ++GAS   +D  G+TPLI A     + +V +LLD
Sbjct: 117  QKGASPNFKDSMGYTPLIHAVKMNDITMVRLLLD 16
>23478
          Length = 909

 Score = 32.0 bits (71), Expect = 3.2,   Method: Composition-based stats.
 Identities = 18/58 (31%), Positives = 28/58 (48%), Gaps = 6/58 (10%)
 Frame = +1

Query: 2548 ADGAGGPIFNGPHSAEPSWN------SLIKMVSSSTENNGPQTVWTGPWAPHMNSVHM 2599
             DG GG    G H A+ ++        L+ M +   + NG Q   T   APH+++VH+
Sbjct: 328  GDGTGGESIYGGHFADENFKFKHEKECLLSMANRGKDTNGSQFFITTNPAPHLDNVHV 501
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6677905|ref|NP_033175.1| golgi apparatus protein 1
[Mus musculus]
         (1175 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

15386                                                                 161   1e-39
26266                                                                 131   2e-30
10173                                                                  91   3e-18
12956                                                                  33   0.71 
11370                                                                  30   6.6  
>15386
          Length = 639

 Score =  161 bits (408), Expect = 1e-39,   Method: Compositional matrix adjust.
 Identities = 78/203 (38%), Positives = 128/203 (63%), Gaps = 2/203 (0%)
 Frame = -2

Query: 299 SDDFHLDRHLYFACRDDRERFCENTQAGEGRVYKCLFNHKFEESMSEKCREALTTRQKLI 358
           SDDFHLDR LY+AC DDRE  C   ++G G V++CL+       ++ +CR+ L  RQ+L+
Sbjct: 611 SDDFHLDRPLYYACHDDRENLCAEVKSGNGAVFQCLYEQLGSPHLTLECRQKLELRQRLM 432

Query: 359 AQDYKVSYSLAKSCKSDLKKYRCNVENLPRSREARLSYLLMCLESAVHRGRQVSSECQGE 418
           ++D +V ++    C+ D++ Y C +       +++ +++L+CLESA    ++V + C  E
Sbjct: 431 SEDVRVEHTFYSRCREDIEHYGC-LGGTTGHEDSKRAHVLLCLESAHMDEKKVDALCVQE 255

Query: 419 MLDYRRMLMEDFSLSPEIILSCRGEIEHHCSGLHRKGRTLHCLMKVVRGE--KGNLGMNC 476
           ML  R+ L+ED+ ++P+++  C+ EIEHHC+GL   G T+HCLMK+ R    + N+    
Sbjct: 254 MLKVRQRLLEDYQINPDLMAMCKDEIEHHCNGLQPGGHTMHCLMKLARDRQLRDNISDQX 75

Query: 477 QQALQTLIQETDPGADYRIDRAL 499
           +  L  L+QE + G DYR+D+ L
Sbjct: 74  KAQLGRLLQEVNVGEDYRLDKPL 6

 Score = 69.3 bits (168), Expect = 9e-12,   Method: Compositional matrix adjust.
 Identities = 60/211 (28%), Positives = 99/211 (46%), Gaps = 17/211 (8%)
 Frame = -2

Query: 809  TEDIRLEPDLYEACKSDIKNYCSTVQYGNAQIIECLKE--NKKQLSTRCHQKVFKLQETE 866
            ++D  L+  LY AC  D +N C+ V+ GN  + +CL E      L+  C QK+   Q   
Sbjct: 611  SDDFHLDRPLYYACHDDRENLCAEVKSGNGAVFQCLYEQLGSPHLTLECRQKLELRQRLM 432

Query: 867  MMDPELDYTLMRVCKQMIKRF------CPEADSKT--MLQCLKQ-NKNSELMDPKCKQMI 917
              D  +++T    C++ I+ +          DSK   +L CL+  + + + +D  C Q +
Sbjct: 431  SEDVRVEHTFYSRCREDIEHYGCLGGTTGHEDSKRAHVLLCLESAHMDEKKVDALCVQEM 252

Query: 918  TKRQITQNTDYRLNPVLRKACKADIPKFCHGILTKAKDDSELEGQVISCLKLRYADQRLS 977
             K +     DY++NP L   CK +I   C+G+        +  G  + CL     D++L 
Sbjct: 251  LKVRQRLLEDYQINPDLMAMCKDEIEHHCNGL--------QPGGHTMHCLMKLARDRQLR 96

Query: 978  SDCEDQIRI----IIQESAL--DYRLDPQLQ 1002
             +  DQ +     ++QE  +  DYRLD  LQ
Sbjct: 95   DNISDQXKAQLGRLLQEVNVGEDYRLDKPLQ 3

 Score = 63.2 bits (152), Expect = 6e-10,   Method: Compositional matrix adjust.
 Identities = 54/212 (25%), Positives = 100/212 (47%), Gaps = 17/212 (8%)
 Frame = -2

Query: 741 QMKDFRFSYKFKMACKEDVLKLCPNIKKKVDVVI-CLSTTVRNDTLQEAKEHRVSLKCRK 799
           Q  DF        AC +D   LC  +K     V  CL   + +  L        +L+CR+
Sbjct: 614 QSDDFHLDRPLYYACHDDRENLCAEVKSGNGAVFQCLYEQLGSPHL--------TLECRQ 459

Query: 800 QLRVEELEMTEDIRLEPDLYEACKSDIKNY-CSTVQYGN-----AQIIECLKE---NKKQ 850
           +L + +  M+ED+R+E   Y  C+ DI++Y C     G+     A ++ CL+    ++K+
Sbjct: 458 KLELRQRLMSEDVRVEHTFYSRCREDIEHYGCLGGTTGHEDSKRAHVLLCLESAHMDEKK 279

Query: 851 LSTRCHQKVFKLQETEMMDPELDYTLMRVCKQMIKRFCP--EADSKTMLQCLKQNKNSEL 908
           +   C Q++ K+++  + D +++  LM +CK  I+  C   +    TM   +K  ++ +L
Sbjct: 278 VDALCVQEMLKVRQRLLEDYQINPDLMAMCKDEIEHHCNGLQPGGHTMHCLMKLARDRQL 99

Query: 909 MDPKCKQMITK-----RQITQNTDYRLNPVLR 935
            D    Q   +     +++    DYRL+  L+
Sbjct: 98  RDNISDQXKAQLGRLLQEVNVGEDYRLDKPLQ 3

 Score = 51.2 bits (121), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 45/190 (23%), Positives = 84/190 (44%), Gaps = 7/190 (3%)
 Frame = -2

Query: 186 CAEEPVGKGYMVSCLVDHRGNI-TEYQCHQYITKMTAIIFSDYRLICGFMDDCKNDINLL 244
           CAE   G G +  CL +  G+     +C Q +     ++  D R+   F   C+ DI   
Sbjct: 548 CAEVKSGNGAVFQCLYEQLGSPHLTLECRQKLELRQRLMSEDVRVEHTFYSRCREDIEHY 369

Query: 245 KCGSIRLGEKDAHSQGEVVSCLEKGLVKEAEEKEPKIQVSELCKKAILRVAELSSDDFHL 304
            C     G +D+  +  V+ CLE   + E        +V  LC + +L+V +   +D+ +
Sbjct: 368 GCLGGTTGHEDS-KRAHVLLCLESAHMDEK-------KVDALCVQEMLKVRQRLLEDYQI 213

Query: 305 DRHLYFACRDDRERFCENTQAGEGRVYKCLF----NHKFEESMSEKCREALT--TRQKLI 358
           +  L   C+D+ E  C   Q G G    CL     + +  +++S++ +  L    ++  +
Sbjct: 212 NPDLMAMCKDEIEHHCNGLQPG-GHTMHCLMKLARDRQLRDNISDQXKAQLGRLLQEVNV 36

Query: 359 AQDYKVSYSL 368
            +DY++   L
Sbjct: 35  GEDYRLDKPL 6

 Score = 50.1 bits (118), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 38/165 (23%), Positives = 70/165 (42%)
 Frame = -2

Query: 492 DYRIDRALNEACESVIQTACKHIRSGDPMILSCLMEHLYTEKMVEDCEHRLLELQYFISR 551
           D+ +DR L  AC    +  C  ++SG+  +  CL E L +  +  +C  +L   Q  +S 
Sbjct: 605 DFHLDRPLYYACHDDRENLCAEVKSGNGAVFQCLYEQLGSPHLTLECRQKLELRQRLMSE 426

Query: 552 DWKLDPVLYRKCQGDASRLCHTHGWNETSELMPPGAVFSCLYRHAYRTEEQGRRLSRECR 611
           D +++   Y +C+ D        G     E      V  CL   A+  E   +++   C 
Sbjct: 425 DVRVEHTFYSRCREDIEHY-GCLGGTTGHEDSKRAHVLLCL-ESAHMDE---KKVDALCV 261

Query: 612 AEVQRILHQRAMDVKLDPALQDKCLIDLGKWCSEKTETGQELECL 656
            E+ ++  +   D +++P L   C  ++   C+     G  + CL
Sbjct: 260 QEMLKVRQRLLEDYQINPDLMAMCKDEIEHHCNGLQPGGHTMHCL 126

 Score = 49.7 bits (117), Expect = 8e-06,   Method: Compositional matrix adjust.
 Identities = 39/174 (22%), Positives = 75/174 (43%), Gaps = 7/174 (4%)
 Frame = -2

Query: 678 ESEDIQIEALLMRACEPIIQNFCHDVADNQIDSGDLMECLIQNKHQKDMNEKCAIGVTHF 737
           +S+D  ++  L  AC    +N C +V      +G + +CL +      +  +C   +   
Sbjct: 614 QSDDFHLDRPLYYACHDDRENLCAEVKSG---NGAVFQCLYEQLGSPHLTLECRQKLELR 444

Query: 738 QLVQMKDFRFSYKFKMACKEDVLKL-------CPNIKKKVDVVICLSTTVRNDTLQEAKE 790
           Q +  +D R  + F   C+ED+               K+  V++CL +           E
Sbjct: 443 QRLMSEDVRVEHTFYSRCREDIEHYGCLGGTTGHEDSKRAHVLLCLESA-------HMDE 285

Query: 791 HRVSLKCRKQLRVEELEMTEDIRLEPDLYEACKSDIKNYCSTVQYGNAQIIECL 844
            +V   C +++      + ED ++ PDL   CK +I+++C+ +Q G    + CL
Sbjct: 284 KKVDALCVQEMLKVRQRLLEDYQINPDLMAMCKDEIEHHCNGLQPG-GHTMHCL 126

 Score = 44.7 bits (104), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 37/143 (25%), Positives = 62/143 (43%), Gaps = 4/143 (2%)
 Frame = -2

Query: 869  DPELDYTLMRVCKQMIKRFCPEADSKT--MLQCLKQNKNSELMDPKCKQMITKRQITQNT 926
            D  LD  L   C    +  C E  S    + QCL +   S  +  +C+Q +  RQ   + 
Sbjct: 605  DFHLDRPLYYACHDDRENLCAEVKSGNGAVFQCLYEQLGSPHLTLECRQKLELRQRLMSE 426

Query: 927  DYRLNPVLRKACKADIPKF-CHGILTKAKDDSELEGQVISCLKLRYADQR-LSSDCEDQI 984
            D R+       C+ DI  + C G  T  +D       V+ CL+  + D++ + + C  ++
Sbjct: 425  DVRVEHTFYSRCREDIEHYGCLGGTTGHEDSKR--AHVLLCLESAHMDEKKVDALCVQEM 252

Query: 985  RIIIQESALDYRLDPQLQLHCSD 1007
              + Q    DY+++P L   C D
Sbjct: 251  LKVRQRLLEDYQINPDLMAMCKD 183

 Score = 44.3 bits (103), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 41/181 (22%), Positives = 72/181 (39%), Gaps = 5/181 (2%)
 Frame = -2

Query: 924  QNTDYRLNPVLRKACKADIPKFCHGILTKAKDDSELEGQVISCLKLRYADQRLSSDCEDQ 983
            Q+ D+ L+  L  AC  D    C  + +         G V  CL  +     L+ +C  +
Sbjct: 614  QSDDFHLDRPLYYACHDDRENLCAEVKSG-------NGAVFQCLYEQLGSPHLTLECRQK 456

Query: 984  IRIIIQESALDYRLDPQLQLHCSDXXXXXX---XXXXXXXXXXXXXXXCLKVNLLKIKT- 1039
            + +  +  + D R++      C +                        CL+   +  K  
Sbjct: 455  LELRQRLMSEDVRVEHTFYSRCREDIEHYGCLGGTTGHEDSKRAHVLLCLESAHMDEKKV 276

Query: 1040 -ELCKKEVLNMLKESKADIFVDPVLHTACALDIKHHCAAITPGRGRQMSCLMEALEDKRV 1098
              LC +E+L + +    D  ++P L   C  +I+HHC  + PG G  M CLM+   D+++
Sbjct: 275  DALCVQEMLKVRQRLLEDYQINPDLMAMCKDEIEHHCNGLQPG-GHTMHCLMKLARDRQL 99

Query: 1099 R 1099
            R
Sbjct: 98   R 96

 Score = 40.8 bits (94), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 49/205 (23%), Positives = 92/205 (44%), Gaps = 10/205 (4%)
 Frame = -2

Query: 624 DVKLDPALQDKCLIDLGKWCSE-KTETGQELECLQDHLDD--LAVECRDIVGNLTELESE 680
           D  LD  L   C  D    C+E K+  G   +CL + L    L +ECR  +     L SE
Sbjct: 605 DFHLDRPLYYACHDDRENLCAEVKSGNGAVFQCLYEQLGSPHLTLECRQKLELRQRLMSE 426

Query: 681 DIQIEALLMRACEPIIQNF-CHDVADNQIDS--GDLMECLIQNKH--QKDMNEKCAIGVT 735
           D+++E      C   I+++ C        DS    ++ CL ++ H  +K ++  C   + 
Sbjct: 425 DVRVEHTFYSRCREDIEHYGCLGGTTGHEDSKRAHVLLCL-ESAHMDEKKVDALCVQEML 249

Query: 736 HFQLVQMKDFRFSYKFKMACKEDVLKLCPNIKKKVDVVICLSTTVRNDTLQEAKEHRVSL 795
             +   ++D++ +      CK+++   C  ++     + CL    R+  L++     +S 
Sbjct: 248 KVRQRLLEDYQINPDLMAMCKDEIEHHCNGLQPGGHTMHCLMKLARDRQLRD----NISD 81

Query: 796 KCRKQLR--VEELEMTEDIRLEPDL 818
           + + QL   ++E+ + ED RL+  L
Sbjct: 80  QXKAQLGRLLQEVNVGEDYRLDKPL 6
>26266
          Length = 439

 Score =  131 bits (329), Expect = 2e-30,   Method: Compositional matrix adjust.
 Identities = 63/146 (43%), Positives = 100/146 (68%), Gaps = 5/146 (3%)
 Frame = +2

Query: 590 SCLYRH--AYRTEEQGRRLSRECRAEVQRILHQRAMDVKLDPALQDKCLIDLGKWCS--- 644
           +CL+RH   +  + Q   L+R C   VQR++ QRA  V L+PA++D C+++LG  CS   
Sbjct: 2   ACLHRHFRHHANDNQVAPLTRGCIFAVQRVMQQRAHSVDLNPAIEDACMLELGDVCSDDK 181

Query: 645 EKTETGQELECLQDHLDDLAVECRDIVGNLTELESEDIQIEALLMRACEPIIQNFCHDVA 704
           E T+ G E+ECLQ++ D L+ +C++ + N TE ESEDI ++ +LM+AC P+I+ FC +  
Sbjct: 182 EATQKGAEIECLQENYDALSPKCKEAIANFTEEESEDIHMDTILMKACTPMIKKFCEEEL 361

Query: 705 DNQIDSGDLMECLIQNKHQKDMNEKC 730
           DN  ++ D++ECLI++K+  DM +KC
Sbjct: 362 DNDAEADDILECLIEHKNHADMKDKC 439

 Score = 62.8 bits (151), Expect = 7e-10,   Method: Compositional matrix adjust.
 Identities = 39/111 (35%), Positives = 58/111 (52%), Gaps = 9/111 (8%)
 Frame = +2

Query: 812 IRLEPDLYEACKSDIKNYCS----TVQYGNAQIIECLKENKKQLSTRCHQKVFKLQETEM 867
           + L P + +AC  ++ + CS      Q G    IECL+EN   LS +C + +    E E 
Sbjct: 113 VDLNPAIEDACMLELGDVCSDDKEATQKGAE--IECLQENYDALSPKCKEAIANFTEEES 286

Query: 868 MDPELDYTLMRVCKQMIKRFCPE-----ADSKTMLQCLKQNKNSELMDPKC 913
            D  +D  LM+ C  MIK+FC E     A++  +L+CL ++KN   M  KC
Sbjct: 287 EDIHMDTILMKACTPMIKKFCEEELDNDAEADDILECLIEHKNHADMKDKC 439

 Score = 45.1 bits (105), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 32/111 (28%), Positives = 51/111 (45%), Gaps = 3/111 (2%)
 Frame = +2

Query: 240 DINLLKCGSIRLGEKDAHSQGEVVSCLEKGLVKEAEEKEPKIQVSELCKKAILRVAELSS 299
           D  +L+ G +   +K+A  +G  + CL++              +S  CK+AI    E  S
Sbjct: 137 DACMLELGDVCSDDKEATQKGAEIECLQENYDA----------LSPKCKEAIANFTEEES 286

Query: 300 DDFHLDRHLYFACRDDRERFCE---NTQAGEGRVYKCLFNHKFEESMSEKC 347
           +D H+D  L  AC    ++FCE   +  A    + +CL  HK    M +KC
Sbjct: 287 EDIHMDTILMKACTPMIKKFCEEELDNDAEADDILECLIEHKNHADMKDKC 439

 Score = 36.6 bits (83), Expect = 0.062,   Method: Compositional matrix adjust.
 Identities = 17/50 (34%), Positives = 30/50 (60%)
 Frame = +2

Query: 897 LQCLKQNKNSELMDPKCKQMITKRQITQNTDYRLNPVLRKACKADIPKFC 946
           ++CL++N ++  + PKCK+ I      ++ D  ++ +L KAC   I KFC
Sbjct: 206 IECLQENYDA--LSPKCKEAIANFTEEESEDIHMDTILMKACTPMIKKFC 349

 Score = 30.8 bits (68), Expect = 3.6,   Method: Compositional matrix adjust.
 Identities = 20/65 (30%), Positives = 34/65 (52%), Gaps = 3/65 (4%)
 Frame = +2

Query: 793 VSLKCRKQLRVEELEMTEDIRLEPDLYEACKSDIKNYCSTVQYGNAQ---IIECLKENKK 849
           +S KC++ +     E +EDI ++  L +AC   IK +C      +A+   I+ECL E+K 
Sbjct: 236 LSPKCKEAIANFTEEESEDIHMDTILMKACTPMIKKFCEEELDNDAEADDILECLIEHKN 415

Query: 850 QLSTR 854
               +
Sbjct: 416 HADMK 430
>10173
          Length = 634

 Score = 90.9 bits (224), Expect = 3e-18,   Method: Composition-based stats.
 Identities = 41/92 (44%), Positives = 63/92 (68%)
 Frame = +3

Query: 1084 RQMSCLMEALEDKRVRLQPECKKRLNDRIEMWSYAAKVAPADGFSDLAMQVMTSPSKNYI 1143
            RQMSCL+  L++    L   C++ L  R EMW YAA+VAP + FS++   + +SPS+NY 
Sbjct: 3    RQMSCLLSFLDEDPRALSGHCRELLRKRKEMWEYAAQVAPPESFSEIYDSISSSPSRNYF 182

Query: 1144 LSVISGSICILFLIGLMCGRITKRVTRELKDR 1175
            + V+   I I+F++G+ CGR+TKRV  E+K++
Sbjct: 183  VVVLFTLIAIIFIVGISCGRVTKRVRAEVKNK 278
>12956
          Length = 788

 Score = 33.1 bits (74), Expect = 0.71,   Method: Composition-based stats.
 Identities = 14/25 (56%), Positives = 18/25 (72%), Gaps = 1/25 (4%)
 Frame = -1

Query: 315 DRERFCENTQAGEGR-VYKCLFNHK 338
           DRER C+ T   +GR VY+C+F HK
Sbjct: 125 DRERLCKPTVLPDGRTVYRCIFCHK 51
>11370
          Length = 783

 Score = 29.6 bits (65), Expect = 6.6,   Method: Compositional matrix adjust.
 Identities = 14/25 (56%), Positives = 18/25 (72%), Gaps = 1/25 (4%)
 Frame = +3

Query: 315 DRERFCENTQAGEGR-VYKCLFNHK 338
           DRER C+ T   +GR VY+C+F HK
Sbjct: 180 DRERLCKPTVLPDGRTVYRCIFCHK 254
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6678419|ref|NP_033444.1| tripeptidyl peptidase II
[Mus musculus]
         (1262 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

06500                                                                 162   1e-39
31024                                                                  32   2.3  
12336                                                                  31   3.3  
08777                                                                  30   6.5  
06852                                                                  30   6.9  
>06500
          Length = 1045

 Score =  162 bits (409), Expect = 1e-39,   Method: Compositional matrix adjust.
 Identities = 94/247 (38%), Positives = 137/247 (55%), Gaps = 18/247 (7%)
 Frame = -1

Query: 1034 FTEALRDLKIQWMTKL--DSTDIYNELKETYPAYLPLYVARLHQLDAEKERMKRLNEIVD 1091
            + +A+RDLK+ W++KL  DS  +Y ++K+ YP ++P+ +ARL  LD  + R K L EI+ 
Sbjct: 958  YADAVRDLKVSWISKLPADSA-VYEQVKQDYPDHIPVLLARLQVLDTPEARKKNLGEILS 782

Query: 1092 AANAVISHIDQTALAVYIAMKTDPRPDAATIKNDMDKQKSTLIDALCRKG----CALADH 1147
                V+S  D   L +Y  +K+D RPDAATIK DM+K+K  LIDAL ++G     AL+D 
Sbjct: 781  LTQQVLSLTDNNQLLIYNGIKSDQRPDAATIKTDMEKKKGWLIDALIKQGLAQASALSDD 602

Query: 1148 LLHTQPHXXXXXXXXXXXXXXXXS------------TMESLSETYWETTKWTDLFDTKVL 1195
             L T                   S            T++ L  T+ E  K+ +L D KVL
Sbjct: 601  DLDTIATGNATGSTESSGSGEGVSSSSGSSFVTPEITIQDLDNTFVEIQKFAELTDAKVL 422

Query: 1196 IFAYKHALVNKMYGRGLKFATKLVEEKPTKENWKNCIQLMKLLGWTHCASFTENWLPIMY 1255
             F+++HA+++K Y R +K   K  E+K  K +    I+    LGW HCA F+EN LP+ Y
Sbjct: 421  PFSFRHAMIHKHYARVVKLLGKQPEDKCNKASDAIVIEAFNKLGWYHCARFSENALPVKY 242

Query: 1256 PPDYCVF 1262
            PP Y +F
Sbjct: 241  PPSYRLF 221
>31024
          Length = 751

 Score = 31.6 bits (70), Expect = 2.3,   Method: Composition-based stats.
 Identities = 26/84 (30%), Positives = 39/84 (46%), Gaps = 2/84 (2%)
 Frame = -1

Query: 1072 RLHQLDAEKERMKRLNEIVDAANAVISHIDQT--ALAVYIAMKTDPRPDAATIKNDMDKQ 1129
            R   L+  KE    +  ++DA N VI+ + +T   +      KT+ R   AT+KN     
Sbjct: 544  RKQFLETIKEIASSIKTLLDAVNRVIAELPRT*QKMERNRCWKTERRSLYATLKNSATPL 365

Query: 1130 KSTLIDALCRKGCALADHLLHTQP 1153
            KST    L  + C+ A   L T+P
Sbjct: 364  KSTSEILLSTRACS*APTTLCTRP 293
>12336
          Length = 959

 Score = 30.8 bits (68), Expect = 3.3,   Method: Composition-based stats.
 Identities = 14/41 (34%), Positives = 22/41 (53%)
 Frame = -1

Query: 819 LYEMVLTYSFHQPKSGEVTPSCPLLCELLYESEFDSQLWII 859
           L E++    FHQP+         +LC+LL + E D +LW +
Sbjct: 623 LKEVIKPRCFHQPQP-------VVLCQLLQQGEIDEELWAV 522
>08777
          Length = 488

 Score = 30.0 bits (66), Expect = 6.5,   Method: Composition-based stats.
 Identities = 12/35 (34%), Positives = 20/35 (57%)
 Frame = -3

Query: 1212 LKFATKLVEEKPTKENWKNCIQLMKLLGWTHCASF 1246
            LK    L E+   K++WK   QL++L+ W++ A  
Sbjct: 429  LKVQHWLKEDPELKDHWKKTFQLLRLVSWSYAAQL 325
>06852
          Length = 1632

 Score = 30.0 bits (66), Expect = 6.9,   Method: Composition-based stats.
 Identities = 12/35 (34%), Positives = 20/35 (57%)
 Frame = +3

Query: 1212 LKFATKLVEEKPTKENWKNCIQLMKLLGWTHCASF 1246
            LK    L E+   K++WK   QL++L+ W++ A  
Sbjct: 60   LKVQHWLKEDPELKDHWKKTFQLLRLVSWSYAAQL 164
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|75677435|ref|NP_031463.2| aldehyde dehydrogenase 3A2
[Mus musculus]
         (484 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

01811                                                                 160   1e-39
11245                                                                 117   1e-26
27685                                                                  92   5e-19
01545                                                                  91   1e-18
31624                                                                  72   6e-13
25921                                                                  60   3e-09
18652                                                                  50   3e-06
31982                                                                  49   3e-06
33316                                                                  30   2.2  
12841                                                                  30   3.1  
>01811
          Length = 1288

 Score =  160 bits (405), Expect = 1e-39,   Method: Compositional matrix adjust.
 Identities = 71/133 (53%), Positives = 101/133 (75%)
 Frame = +2

Query: 330 EEIFGPILPIVSVKNVDEAINFINDREKPLALYVFSRNNKLIKRVIDETSSGGVTGNDVI 389
           EE+FGP+LPI+ VK+  EA+  I D+EKPLA+YVFS N+ +++ + + +SSG +  ND I
Sbjct: 2   EEVFGPLLPIMVVKDHHEAVQVITDKEKPLAMYVFSNNSDVVRTLKEGSSSGAILVNDTI 181

Query: 390 MHFTVNSLPFGGVGASGMGAYHGKYSFDTFSHQRPCLLKGLKGESVNKLRYPPNSESKVS 449
           MH  + +LPFGGVG SGMG+YHGK++F+ FSH+R CL K L  ESVN +RYPP SE K+S
Sbjct: 182 MHGGLCTLPFGGVGESGMGSYHGKFTFEAFSHKRACLEKSLAMESVNNIRYPPYSEKKLS 361

Query: 450 WAKFFLLKQFNKG 462
           W ++ ++K+  +G
Sbjct: 362 WLQWLMVKKPRRG 400
>11245
          Length = 993

 Score =  117 bits (292), Expect = 1e-26,   Method: Compositional matrix adjust.
 Identities = 74/243 (30%), Positives = 127/243 (52%), Gaps = 11/243 (4%)
 Frame = +2

Query: 181 ILYTGNTAVGKIVMEAAAKHLTPVTLELGGKSPCYIDRDCDLDVACRRIAWGKYMNCGQT 240
           I +TG+T VGK++    A  +  V LELGG +P  +    +++ A       K+ NCGQT
Sbjct: 98  ISFTGSTQVGKLLFRNCADGIKRVCLELGGNAPFIVFDSANVEKAVDGAMASKFRNCGQT 277

Query: 241 CIAPDYILCEASLQNQIVQKIKETVKDF-YGENIKASPDYERIINLRHFKRLQSLL---- 295
           C++ +    +  + ++ V ++K+ V+    G+   +      +IN   F ++   +    
Sbjct: 278 CVSANRFFVQEGVYDKFVSQLKQRVEALKIGDGKSSDVQIGPLINKMQFDKVSGFVEDAR 457

Query: 296 --KGQKIAFGGEMDE-ATRYLAPTILTDVDPNSKVMQEEIFGPILPIVSVKNVDEAINFI 352
             K   I  G  + E  + + APTI+TDV P++++  EE+FGP++ I+  K+  EA+   
Sbjct: 458 SKKANVIVGGKALQEFGSLFYAPTIVTDVPPSAQLYTEEVFGPVVSIIKFKDEAEAVXQA 637

Query: 353 NDREKPLALYVFSRNNKLIKRVIDETSSGGVTGNDVIMHFTVNSLPFGGVGASGM---GA 409
           ND ++ LA Y +S N + + RV      G V  N+ I+  +    PFGGV  SG+   G+
Sbjct: 638 NDTQRGLAGYFYSDNLQQVFRVAKRLEVGMVGVNEGII--SAPEAPFGGVKESGIGREGS 811

Query: 410 YHG 412
           +HG
Sbjct: 812 HHG 820
>27685
          Length = 735

 Score = 92.0 bits (227), Expect = 5e-19,   Method: Compositional matrix adjust.
 Identities = 69/212 (32%), Positives = 99/212 (46%), Gaps = 3/212 (1%)
 Frame = +2

Query: 33  MVQEREKEILAAIAADLSKSELNAYSHEVITILGEIDFMLGNLPELASARPAKKNLLTMM 92
           ++QERE+E+      D  K    A  +++      I +  G +P L      +   L+  
Sbjct: 26  LIQEREEELARMEVLDTGKPIWEA-RYDIQGCADTIQYYGGIVPTLV----GEHTKLSGG 190

Query: 93  DEAYVQPEPLGVVLIIGAWNYPFVLTMQPLXXXXXXXXXXXXKPSELSENTAKILAELLP 152
             AY   EPLGVV  IGAWNYPF +                 KPS  +  TA +L E+  
Sbjct: 191 SFAYTLREPLGVVGAIGAWNYPFQMAAWKSSPALACGNTMVFKPSPFTPLTAVMLGEIYR 370

Query: 153 QY-LDQDLYAIVNGGIPETTELLKQRFD--HILYTGNTAVGKIVMEAAAKHLTPVTLELG 209
           +  L    Y ++ G   ET +L+    D   + +TG+ A G  +M A A+ +  VTLELG
Sbjct: 371 EAGLPDGCYNVIQGE-GETGQLISHHDDIAKMSFTGSVATGSKIMAACAQGIKHVTLELG 547

Query: 210 GKSPCYIDRDCDLDVACRRIAWGKYMNCGQTC 241
           GKSP  I  D DLD A +      +++ GQ C
Sbjct: 548 GKSPLIIFEDADLDNAVKGAMLANFLSQGQVC 643
>01545
          Length = 604

 Score = 90.5 bits (223), Expect = 1e-18,   Method: Compositional matrix adjust.
 Identities = 39/67 (58%), Positives = 53/67 (79%)
 Frame = -1

Query: 396 SLPFGGVGASGMGAYHGKYSFDTFSHQRPCLLKGLKGESVNKLRYPPNSESKVSWAKFFL 455
           +LPFGGVG SGMG+YHGK++F+ FSH+R CL K L  ESVN +RYPP SE K+SW ++ +
Sbjct: 595 TLPFGGVGESGMGSYHGKFTFEAFSHKRACLEKSLAMESVNNIRYPPYSEKKLSWLQWLM 416

Query: 456 LKQFNKG 462
           +K+  +G
Sbjct: 415 VKKPRRG 395
>31624
          Length = 2324

 Score = 71.6 bits (174), Expect = 6e-13,   Method: Compositional matrix adjust.
 Identities = 68/282 (24%), Positives = 111/282 (39%), Gaps = 14/282 (4%)
 Frame = +1

Query: 101 PLGVVLIIGAWNYPFVLTMQPLXXXXXXXXXXXXKPSELSENTAKILAELLPQYLDQDLY 160
           PLGVV  I  +N+P ++ +               KPSE       IL ELL +       
Sbjct: 46  PLGVVAGITPFNFPAMIPLWMFPMAAVCGNTCILKPSERDPGATMILMELLQEAGMPPGI 225

Query: 161 AIVNGGIPETTELLKQRFD--HILYTGNTAVGKIVMEAAAKHLTPVTLELGGKSPCYIDR 218
             V  G  ++   +    D   I + G+   G+ + E  +K+   V   +G K+   I  
Sbjct: 226 VNVIHGRHDSVNFICDNPDIKAISFVGSDQAGEYIYERGSKNGKRVQANMGAKNHGVIMP 405

Query: 219 DCDLDVACRRIAWGKYMNCGQTCIAPDYILCEASLQNQIVQKIKETVKDFYGENIKASPD 278
           D + +    ++    +   GQ C+A    +     +  I + ++           +   D
Sbjct: 406 DANKESTLTQLVGAAFGAAGQRCMALSTAVFVGEAKKWIPELVERAKALKVTGGTEKGAD 585

Query: 279 YERIINLRHFKRLQSL------------LKGQKIAFGGEMDEATRYLAPTILTDVDPNSK 326
              +I+    KR+  L            L G+ +   G   E   ++ PTIL  VDPN K
Sbjct: 586 LGPLISPESKKRVCDLVQAGVDAGADLLLDGRGVQVPGY--EKGNFVGPTILHQVDPNMK 759

Query: 327 VMQEEIFGPILPIVSVKNVDEAINFINDREKPLALYVFSRNN 368
              EEIFGP+L  + V  +DEAI+ +N         +F+ N 
Sbjct: 760 CYTEEIFGPVLVSMEVDTLDEAIDIVNANPYGNGTAIFTTNG 885
>25921
          Length = 425

 Score = 59.7 bits (143), Expect = 3e-09,   Method: Composition-based stats.
 Identities = 34/101 (33%), Positives = 54/101 (53%), Gaps = 3/101 (2%)
 Frame = +2

Query: 162 IVNGGIPETTELLKQRFD--HILYTGNTAVGKIVMEAAAK-HLTPVTLELGGKSPCYIDR 218
           ++NG  P     + +  D   + +TG+  VG+I+MEAAAK +L  ++LELGGKSP  +  
Sbjct: 11  VINGFGPTAGAAISEHPDINKVAFTGSVDVGRIIMEAAAKSNLKRISLELGGKSPVVVFD 190

Query: 219 DCDLDVACRRIAWGKYMNCGQTCIAPDYILCEASLQNQIVQ 259
           D D+D A        + N GQ+C A         + ++ V+
Sbjct: 191 DADIDFAVETXHEALFSNHGQSCCAGSRTYVHEKIYDKFVE 313
>18652
          Length = 759

 Score = 49.7 bits (117), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 31/137 (22%), Positives = 69/137 (50%), Gaps = 2/137 (1%)
 Frame = -1

Query: 293 SLLKGQKIAFGGE-MDEATRYLAPTILTDVDPNSKVMQEEIFGPILPIVSVKNVDEAINF 351
           ++ +G KI +GG+ ++    ++ PTI++ +  ++ V+  E F PI+  +   N+DEAI +
Sbjct: 615 AVAQGGKIEYGGKPIERPGNFVEPTIISGLSHDAPVVHRETFAPIVYALKTTNLDEAIAW 436

Query: 352 INDREKPLALYVFSRN-NKLIKRVIDETSSGGVTGNDVIMHFTVNSLPFGGVGASGMGAY 410
            N+ ++ L   +F+++   + K +  + S  G+   ++          FGG   +G G  
Sbjct: 435 NNEVKQGLTSSLFTKDLANVFKWIGPKGSDCGIVNVNIPTSGAEIGGAFGGEKHTGGGRE 256

Query: 411 HGKYSFDTFSHQRPCLL 427
            G  ++  +  +  C +
Sbjct: 255 SGSDAWKQYMRRSTCTI 205
>31982
          Length = 555

 Score = 49.3 bits (116), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 31/112 (27%), Positives = 57/112 (50%), Gaps = 6/112 (5%)
 Frame = +2

Query: 296 KGQKIAFGGEMDEATR------YLAPTILTDVDPNSKVMQEEIFGPILPIVSVKNVDEAI 349
           +G ++  GGE    +       YL+P ILT    +  V+QEE+FG +L +++    +E +
Sbjct: 5   QGARVVCGGERVTPSAELSGGIYLSPCILTGCHDDMTVVQEEVFGSVLSVLTFDTQEEVV 184

Query: 350 NFINDREKPLALYVFSRNNKLIKRVIDETSSGGVTGNDVIMHFTVNSLPFGG 401
              NB E  LA  +F+++ K   +V  +  +G +  N+  ++     +PFGG
Sbjct: 185 RRANBTELGLAGGIFTKDLKRAHQVAQQLEAGSLYINNYNVYPV--GVPFGG 334
>33316
          Length = 632

 Score = 30.0 bits (66), Expect = 2.2,   Method: Compositional matrix adjust.
 Identities = 18/50 (36%), Positives = 24/50 (48%)
 Frame = -2

Query: 180 HILYTGNTAVGKIVMEAAAKHLTPVTLELGGKSPCYIDRDCDLDVACRRI 229
            +L+  N  + K V E     L  V L+L   S CY  +D DL V C +I
Sbjct: 400 FVLFKSNFVLTKGV*EMICASLMTVLLKL---SQCYFIQDIDLTVVCFKI 260
>12841
          Length = 1364

 Score = 29.6 bits (65), Expect = 3.1,   Method: Compositional matrix adjust.
 Identities = 17/66 (25%), Positives = 35/66 (53%)
 Frame = +1

Query: 280 ERIINLRHFKRLQSLLKGQKIAFGGEMDEATRYLAPTILTDVDPNSKVMQEEIFGPILPI 339
           ER+INL  ++  Q+L +G KI    +++  T  +    ++D+ PN     + ++  + P+
Sbjct: 232 ERVINLNTYQAKQALYRGFKIIT--DLERETSTVNQIAVSDMGPN----LDRLWSYVCPL 393

Query: 340 VSVKNV 345
              +NV
Sbjct: 394 TKGRNV 411
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|160333195|ref|NP_035998.2| peroxisomal delta3,
delta2-enoyl-Coenzyme A isomerase isoform b [Mus musculus]
         (358 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

37516                                                                 159   2e-39
13420                                                                 100   2e-21
13881                                                                  89   2e-18
11398                                                                  35   0.067
05195                                                                  29   3.7  
08426                                                                  27   9.6  
>37516
          Length = 358

 Score =  159 bits (402), Expect = 2e-39,   Method: Compositional matrix adjust.
 Identities = 73/119 (61%), Positives = 94/119 (78%), Gaps = 1/119 (0%)
 Frame = -1

Query: 159 DYYCSGNDLTNF-TSATGGIEEAASNGAVLLRDFVNSFIDFPKPLVAVVNGPAVGISVTL 217
           +YY SGNDL NF  SA     + A  G +++ + V + ID+PKP++A+VNGPAVGI+VTL
Sbjct: 358 EYYSSGNDLNNFLQSAPQTTPQDARPGTLVVENIVKTLIDYPKPVIALVNGPAVGIAVTL 179

Query: 218 LGLFDAVFASDRATFHTPFSQLGQSPEACSSYTFPKMMGSAKAAEMLLFGKKLTAREAW 276
           LGL DAV+ SDRATFHTPF+QL Q+PE CSSY FP++MG AKA EMLLF +K+TA+EA+
Sbjct: 178 LGLCDAVYCSDRATFHTPFTQLAQNPEGCSSYIFPRLMGGAKATEMLLFNQKITAQEAY 2
>13420
          Length = 2884

 Score = 99.8 bits (247), Expect = 2e-21,   Method: Compositional matrix adjust.
 Identities = 49/94 (52%), Positives = 63/94 (67%)
 Frame = -1

Query: 262  EMLLFGKKLTAREAWAQGLVTEVFPESTFETEVWTRLKTYAKLPPNAMRISKELIRKNEK 321
            E+LLF KK+TA+EA  + LVT VFPE  F+ E    +  Y  LPP +++ SK L R  E+
Sbjct: 2884 ELLLFNKKITAQEACDRNLVTRVFPEDVFQKETEALVSYYGSLPPQSLKYSKTLNRAAER 2705

Query: 322  EKLYAVNAEECTTLQARWLSEECMNAIMSFVSRK 355
            E L++VN  EC  L  RW S+EC+NAIMSF SRK
Sbjct: 2704 ELLHSVNQAECELLVERWQSKECINAIMSFFSRK 2603
>13881
          Length = 1594

 Score = 89.4 bits (220), Expect = 2e-18,   Method: Compositional matrix adjust.
 Identities = 64/214 (29%), Positives = 102/214 (47%), Gaps = 4/214 (1%)
 Frame = +3

Query: 115 ITKITFNRPTKKNAISFQMYRDIILALKNASTDNTV-MAVFTGTGDYYCSGNDLTNFTSA 173
           +  +  NRP   NA+S  +  D+  AL+    DN+V   V TG+   + +G D+ +    
Sbjct: 141 VAVVRMNRPRTFNALSDALMADVTAALQQLDQDNSVGCIVLTGSDRAFAAGADVPDLHKK 320

Query: 174 TGGIEEAASNGAVLLRDFVNSFIDFPK---PLVAVVNGPAVGISVTLLGLFDAVFASDRA 230
           T   E+      V+ +DF   F    K   P++A VNG A+G    +  + D V+A D+A
Sbjct: 321 T--FED------VIEQDFPAQFYSISKCRKPIIAAVNGYALGGGXEIAMMCDIVYAGDKA 476

Query: 231 TFHTPFSQLGQSPEACSSYTFPKMMGSAKAAEMLLFGKKLTAREAWAQGLVTEVFPESTF 290
            F  P   LG  P A  +    + +G +KA EM++   K+TA EA   GLV++VFP S  
Sbjct: 477 LFAQPEVTLGTLPGAGGTQRLIRAVGKSKAMEMVISANKITAHEAERMGLVSKVFPASEV 656

Query: 291 ETEVWTRLKTYAKLPPNAMRISKELIRKNEKEKL 324
                   +  A     A+ + KE +  +++  L
Sbjct: 657 LDAAVQTAEKIAGFSRVAVALCKEAVNASQEMSL 758
>11398
          Length = 3234

 Score = 34.7 bits (78), Expect = 0.067,   Method: Compositional matrix adjust.
 Identities = 22/74 (29%), Positives = 32/74 (43%)
 Frame = -3

Query: 212  GISVTLLGLFDAVFASDRATFHTPFSQLGQSPEACSSYTFPKMMGSAKAAEMLLFGKKLT 271
            G  V L   +    A  + T   P   LG  P A  +   PK++    A +M+L GK + 
Sbjct: 3217 GFEVALACQYRVAVADKKTTVALPEVMLGLLPGAGGTQRLPKLVPIPTALDMMLTGKTIK 3038

Query: 272  AREAWAQGLVTEVF 285
            A  A   GLV ++ 
Sbjct: 3037 ADRAKKMGLVDQLV 2996
>05195
          Length = 2092

 Score = 28.9 bits (63), Expect = 3.7,   Method: Compositional matrix adjust.
 Identities = 16/45 (35%), Positives = 25/45 (55%), Gaps = 2/45 (4%)
 Frame = +3

Query: 105 KDILVTSEDGITKITFNRPTKKNAISFQMYRDI--ILALKNASTD 147
           K I+ TSE G   +     +KKN+ISF +Y  +  ++ L+N   D
Sbjct: 303 KKIVSTSERGSMNLILTLRSKKNSISFTLYNTL*SVMWLQNTRDD 437
>08426
          Length = 1206

 Score = 27.3 bits (59), Expect = 9.6,   Method: Compositional matrix adjust.
 Identities = 18/64 (28%), Positives = 30/64 (46%), Gaps = 2/64 (3%)
 Frame = -2

Query: 241  QSPEACSSYTFPKMMGSAKAAEMLLFGKKLTAREAWAQGLVTEVFPEST--FETEVWTRL 298
            ++P  CS+  +PK++     A   L G  L    A     +T VF  S+  F  ++WTR 
Sbjct: 1079 ENPNGCSNIAYPKLVVELLPAG--LRGLMLAVMLAALMSTLTSVFNSSSSMFTLDLWTRC 906

Query: 299  KTYA 302
            + + 
Sbjct: 905  RPHC 894
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|20270043|ref|NP_061299.2| adaptor-related protein
complex 3, mu 1 subunit [Mus musculus]
         (418 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

04701                                                                 159   2e-39
08361                                                                 101   7e-22
29016                                                                  49   4e-06
28998                                                                  47   1e-05
06056                                                                  38   0.006
04375                                                                  33   0.26 
09881                                                                  29   3.2  
30493                                                                  29   4.6  
>04701
          Length = 4543

 Score =  159 bits (402), Expect = 2e-39,   Method: Compositional matrix adjust.
 Identities = 115/393 (29%), Positives = 187/393 (47%), Gaps = 26/393 (6%)
 Frame = +2

Query: 52  PHHYLISIYRDKLFFVSVIQTEVPPLFVIE---------FLHRVADTFQDYFGECSEAAI 102
           P+H    I R +   +  +Q  VP L   E         F  +    F +YF E  E +I
Sbjct: 227 PYH----ISRQRDLCLHQVQQPVPRLHHQEKCQCGTGLLFPPQACADFVEYFKELEEESI 394

Query: 103 KDNVVIVYELLEEMLDNGFPLATESNILKELIKPPTILRSVVNSITGSSNVGDTLPTGQL 162
           +DN VI+YELL+E++D G+P  T+S IL+E I                  V    P    
Sbjct: 395 RDNFVIIYELLDEVMDFGYPQTTDSKILQEYI----------TQEGQKLEVAPRPPMAVT 544

Query: 163 SNIPWRRAGVKYTNHEAYPDVVEEIDAIVDRSGSTVFAEIQGVIDACIKLSGMPDLSLSF 222
           + + WR  GVKY  +E + DV+E ++ +V  +G+ + +EI G +   + LSGMP+L L  
Sbjct: 545 NAVSWRSEGVKYRKNEVFLDVIESVNLLVSANGNVLRSEIVGSVKMRVFLSGMPELRLGL 724

Query: 223 MNPRL-------------LDDVSFHPCIRFKRWESERVLSFIPPDGNFRLISYRVSSQNL 269
            +  L             L+DV FH C+R  R+E++R +SFIPPDG F L+SYR+++   
Sbjct: 725 NDKVLFESTGRGKSKSVELEDVKFHQCVRLSRFENDRTISFIPPDGEFELMSYRLNTH-- 898

Query: 270 VAIPVYVKHSISFKENSSCGRFDITIGPKQNMGK--TIEGITVTVHMPKVVLNMNLTPTQ 327
           V   ++V+  I   E     R +  I  K    +  T   + + + +P    +     T 
Sbjct: 899 VKPLIWVESVI---ERHVHSRVEYMIKAKSQFKRRSTANNVEIIIPVPADADSPKFKTTV 1069

Query: 328 GSYTFDPVTKVLAWDVGKITPQKLPSLKGLVNLQSGAPKPEE-NPNLNIQFKIQQLAISG 386
           GS  + P    + W +      K   ++    L S   +  E  P ++I+F+I    +SG
Sbjct: 1070GSCKYVPEINSVIWSIKSFPGGKEFLMRAHFGLPSVENEDAEGRPPISIKFEIPYFTVSG 1249

Query: 387 LKVNRLDMYGEK-YKPFKGVKYVTKAGKFQVRT 418
           ++V  L +  +  Y+    V+Y+T+ G +Q+RT
Sbjct: 1250IQVRYLKIIEKSGYQALPWVRYITQNGDYQLRT 1348

 Score = 41.6 bits (96), Expect = 6e-04,   Method: Compositional matrix adjust.
 Identities = 19/84 (22%), Positives = 41/84 (48%)
 Frame = +3

Query: 4   SLFLINCSGDIFLEKHWKSVVSQSVCDYFFEAQEKAADVENVPPVISTPHHYLISIYRDK 63
           ++++++  G + + ++++  +  SV D F     +  D  NV P+IS  +   + I  + 
Sbjct: 99  AIYILDVKGKVLISRNYRGDIDMSVIDKFMPLVMEGEDDSNVTPIISHGNVTFVYIKYNN 278

Query: 64  LFFVSVIQTEVPPLFVIEFLHRVA 87
           L+ VS  +       V  FLH++ 
Sbjct: 279 LYLVSTTRKNANVALVFSFLHKLV 350
>08361
          Length = 465

 Score =  101 bits (251), Expect = 7e-22,   Method: Compositional matrix adjust.
 Identities = 57/150 (38%), Positives = 87/150 (58%), Gaps = 1/150 (0%)
 Frame = -3

Query: 81  EFLHRVADTFQDYFGECSEAAIKDNVVIVYELLEEMLDNGFPLATESNILKELIKPPTIL 140
           EFLH++A+  Q YFG+ SE  IK+N V++YE+L+E+LD G+P  T++ ILK  I    I 
Sbjct: 460 EFLHKIAEVMQAYFGKISEENIKNNFVLIYEILDEILDYGYPQNTDTGILKTFITQQGIK 281

Query: 141 -RSVVNSITGSSNVGDTLPTGQLSNIPWRRAGVKYTNHEAYPDVVEEIDAIVDRSGSTVF 199
            +S  ++   +S V     TGQ   I WRR G+KY  +E + DV+E ++ ++   G  + 
Sbjct: 280 SQSKEDTAQITSQV-----TGQ---IGWRREGIKYRRNELFLDVLESVNLLMSPQGQVLS 125

Query: 200 AEIQGVIDACIKLSGMPDLSLSFMNPRLLD 229
           A + G I     LSGMP+      +  L+D
Sbjct: 124 AHVAGRIVMKSYLSGMPECKFGINDKVLMD 35
>29016
          Length = 550

 Score = 48.9 bits (115), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 17/34 (50%), Positives = 25/34 (73%)
 Frame = +2

Query: 228 LDDVSFHPCIRFKRWESERVLSFIPPDGNFRLIS 261
           +DD  FH C++  ++E+E  +SFIPPDG F L+S
Sbjct: 29  IDDCQFHQCVKLSKFETEHSISFIPPDGEFELMS 130
>28998
          Length = 569

 Score = 47.0 bits (110), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 16/33 (48%), Positives = 24/33 (72%)
 Frame = +2

Query: 228 LDDVSFHPCIRFKRWESERVLSFIPPDGNFRLI 260
           +DD  FH C++  ++E+E  +SFIPPDG F L+
Sbjct: 29  IDDCQFHQCVKLSKFETEHSISFIPPDGEFELM 127
>06056
          Length = 1228

 Score = 38.1 bits (87), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 20/55 (36%), Positives = 31/55 (56%)
 Frame = -3

Query: 228  LDDVSFHPCIRFKRWESERVLSFIPPDGNFRLISYRVSSQNLVAIPVYVKHSISF 282
            +DD  FH C++  ++E+E  +SFIP  GN       ++S ++V     V HS SF
Sbjct: 1175 IDDCQFHQCVKLSKFETEHSISFIPLXGN-------LNS*DIVRRMTSVCHSESF 1032
>04375
          Length = 2667

 Score = 32.7 bits (73), Expect = 0.26,   Method: Compositional matrix adjust.
 Identities = 21/69 (30%), Positives = 32/69 (46%), Gaps = 1/69 (1%)
 Frame = +3

Query: 64  LFFVSVIQTEVPPLFVIEFLHRVADTFQDYFGECSEAAIKDNVVIVYELLEE-MLDNGFP 122
           L+F   I+ E   L  +E +HR  +    YFG   E  I  N    + +L+E ML     
Sbjct: 294 LYFCCAIEPEDNELLTLEIIHRYVELLDKYFGSVCELDIIFNFEKAFFMLDEFMLGGEVQ 473

Query: 123 LATESNILK 131
             ++ N+LK
Sbjct: 474 ETSKKNVLK 500
>09881
          Length = 600

 Score = 29.3 bits (64), Expect = 3.2,   Method: Compositional matrix adjust.
 Identities = 24/92 (26%), Positives = 35/92 (38%), Gaps = 15/92 (16%)
 Frame = +3

Query: 23  VVSQSVCDYFFEAQEKAADVENVPPVISTPHHYLISIYRDKLFF-------VSVIQTEVP 75
           VV+ + CD    A  K   V NV   +      L   + D +         V V+  +  
Sbjct: 291 VVAFTACDAEVGASAKQGIVSNVKNTVCNVKRILGLTFEDPVTQEYLASSPVKVVNQKNQ 470

Query: 76  PLFVIEF--------LHRVADTFQDYFGECSE 99
           P+F +EF         HR  +  Q  FG C+E
Sbjct: 471 PMFEVEFKERTAVHCRHRRRNDLQKDFGNCTE 566
>30493
          Length = 657

 Score = 28.9 bits (63), Expect = 4.6,   Method: Compositional matrix adjust.
 Identities = 28/137 (20%), Positives = 60/137 (43%), Gaps = 9/137 (6%)
 Frame = -2

Query: 290 RFDITIGPKQNMGKTIEGITVTVHMPKVVLN---MNLTPTQGSYTFDPVTKVLAWDVGKI 346
           + ++ +  K N   ++    V + +P   LN   + +   +G   +      + W + +I
Sbjct: 563 KMEVKVVVKSNFKPSLAAQKVELRIP-TPLNTSGVQVICMKGRAKYKASDNAIVWKIKRI 387

Query: 347 TPQKLPSLKGLVNLQSGAPKPE-ENPNLNIQFKIQQLAISGLKVNRLDMYGEK-----YK 400
              K   L   + L + + K +   P L++ F++   A SG KV  L ++  K     + 
Sbjct: 386 GGMKECQLSAEIELLATSDKKKWTRPPLSMNFEVP-FAPSGFKVRYLKVFESKINYSDHD 210

Query: 401 PFKGVKYVTKAGKFQVR 417
             K V+Y+ ++G ++ R
Sbjct: 209 VIKWVRYIGRSGLYETR 159
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|34328209|ref|NP_035959.2| inosine 5'-phosphate
dehydrogenase 1 [Mus musculus]
         (514 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

29232                                                                 129   2e-39
09128                                                                  60   2e-09
>29232
          Length = 368

 Score =  129 bits (324), Expect(2) = 2e-39,   Method: Compositional matrix adjust.
 Identities = 63/97 (64%), Positives = 76/97 (78%)
 Frame = +1

Query: 110 FEQGFITDPVVLSPSHTVGDVLEAKIQHGFSGIPITATGTMGSKLVGIVTSRDIDFLAEK 169
           +EQGFI DPVV+SP H V DV+EAK + GFSGIP+T +G MG KLVG+VT RD+DFL + 
Sbjct: 1   YEQGFILDPVVMSPMHRVADVMEAKKRFGFSGIPVTESGHMGEKLVGLVTQRDVDFLTQD 180

Query: 170 DHTTLLSEVMTPRVELVVAPAGVTLKEANEILQRSKK 206
            + T LSEVMT   +L+VA  GVTLKEAN ILQ+SKK
Sbjct: 181 QYNTPLSEVMTRFEDLIVATHGVTLKEANTILQKSKK 291

 Score = 51.6 bits (122), Expect(2) = 2e-39,   Method: Composition-based stats.
 Identities = 23/30 (76%), Positives = 28/30 (93%)
 Frame = +2

Query: 202 QRSKKGKLPIVNDQDELVAIIARTDLKKNR 231
           +++KKGKLPIVN+Q ELVA+IARTD KKNR
Sbjct: 278 RKAKKGKLPIVNEQGELVALIARTDTKKNR 367
>09128
          Length = 1107

 Score = 60.1 bits (144), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 34/80 (42%), Positives = 48/80 (60%)
 Frame = +2

Query: 317 GVDGLRVGMGCGSICITQEVMACGRPQGTAVYKVAEYARRFGVPVIADGGIQTVGHVVKA 376
           G D ++VG+G GS+C T++    G PQ +AV + A+ A   G  +I+DGG    G V KA
Sbjct: 2   GADIIKVGIGPGSVCTTRKKTGVGYPQLSAVLECADAAHGLGGHIISDGGCTCPGDVSKA 181

Query: 377 LALGASTVMMGSLLAATTEA 396
              GA  VM+G +LA  TE+
Sbjct: 182 FGAGADFVMLGGMLAGHTES 241
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|46852276|ref|NP_766182.2| DEAH (Asp-Glu-Ala-His) box
polypeptide 29 [Mus musculus]
         (1365 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

12784                                                                 161   2e-39
03659                                                                 154   3e-37
09272                                                                 153   6e-37
21806                                                                 147   3e-35
19545                                                                 147   3e-35
20747                                                                 100   4e-21
18403                                                                  96   9e-20
17966                                                                  93   8e-19
19948                                                                  79   2e-14
35632                                                                  65   3e-10
07993                                                                  33   0.67 
04440                                                                  32   1.7  
>12784
          Length = 2199

 Score =  161 bits (407), Expect = 2e-39,   Method: Compositional matrix adjust.
 Identities = 112/358 (31%), Positives = 183/358 (51%), Gaps = 3/358 (0%)
 Frame = -1

Query: 923  RKIVLATNIAETGITIPDVVFVIDTGRTKENKYHESSQMSSLVETFVSKASALQRQGRAG 982
            RK+V++TNIAET +TI  VVFVID G  K+  Y+   ++ SL+ T +SKASA QR GRAG
Sbjct: 2199 RKVVVSTNIAETSLTIDGVVFVIDPGFAKQKVYNPRIRVESLLVTAISKASAQQRAGRAG 2020

Query: 983  RVRDGFCFRLYTRERF-EGFLDYSVPEILRVPLEELCLHIMKCDLGSPEDFLSKALDPPQ 1041
            R R G CFRLYT + + +   + + PEILR  L  + L + K  LG  +      +DPP 
Sbjct: 2019 RTRPGKCFRLYTEKAYTQEMQENTYPEILRSNLGSVVLQLKK--LGIDDLVHFDFMDPPA 1846

Query: 1042 LQVISNAMNLLRKIGACEPNEPKLTPLGQHLAALPVNVKIGKMLIFGAIFGCLEPVATLA 1101
             + +  A+ LL  +   + ++ +LT LG  +A  P++ ++ KM+I      C   + ++ 
Sbjct: 1845 PETLMRALELLNYLAGLD-DDGELTELGSMMAEFPLDPQLAKMVIASCDSNCSNEILSIT 1669

Query: 1102 AVMTEKSPFITPIGRKDEADLAKSSLAVADSDHLTIYNAYLGWKKAQQEGGFRSEISYCQ 1161
            ++++    F+ P   K  AD AK   A  D DHLT+ N Y  +K+  ++        +C 
Sbjct: 1668 SMLSVPQCFVRPTEAKKAADEAKMRFAHIDGDHLTLLNVYHAFKQNHEDP------QWCY 1507

Query: 1162 RNFLNRTSLLTLEDVKQELMKLVKAAGFSSSPSWEGRKGPQTLSFQDIAL-LKAVLAAGL 1220
             NF+N  SL + ++V+Q+L +++          +  R+     + +D  L ++  L  G 
Sbjct: 1506 DNFINYRSLKSADNVRQQLARIMD--------RFNLRRSSTEFTSRDYYLNIRRALVNGF 1351

Query: 1221 YDSVGKIMCTKSVDVTEKLACMVETAQGK-AQVHPSSVNRDLQTYGWLLYQEKVRYTR 1277
            +  V  +         E+    +     +  Q+HPS+V        W+LY E V  T+
Sbjct: 1350 FMQVAHL---------ERTGHYLTVKDNQVVQLHPSTVLD--HKPEWVLYNEFVLTTK 1210
>03659
          Length = 1566

 Score =  154 bits (388), Expect = 3e-37,   Method: Compositional matrix adjust.
 Identities = 80/190 (42%), Positives = 119/190 (62%)
 Frame = -1

Query: 564 LLKERQQLPVFKHRDSIVETLKRHRVVVVAGETGSGKSTQVPHFLLEDLLLDECGARKCN 623
           +L++RQ LP++K +D +++ +  +++++V GETGSGK+TQ+  +L E          +  
Sbjct: 540 ILEQRQGLPIYKLKDELLKAVHDNQILIVIGETGSGKTTQITQYLAESGY-----TTRGK 376

Query: 624 IVCTQPRRISAVSLATRVCEELGCESGPGGRNSLCGYQIRMESRASESTRLLYCTTGVLL 683
           I CTQPRR++A+S+A RV EE GC  G        GY IR E   S  T++ Y T G+LL
Sbjct: 375 IGCTQPRRVAAMSVAKRVSEEFGCRLG-----QEVGYTIRFEDCTSPETKIKYMTDGMLL 211

Query: 684 RKLQEDGLLADVSHVIVDEVHERSVQSDFLLVILKEILQKRSDLHLILMSATVDSDKFST 743
           R+   D  L   S V++DE HER++ +D L  +LK+ ++KR DL LI+ SAT+D+ KFS 
Sbjct: 210 RECLIDRDLMQYSIVMLDEAHERTIHTDVLFGLLKQAVKKRPDLKLIVTSATLDAVKFSQ 31

Query: 744 YFTHCPILRI 753
           YF   PI  I
Sbjct: 30  YFFEAPIFTI 1
>09272
          Length = 890

 Score =  153 bits (386), Expect = 6e-37,   Method: Compositional matrix adjust.
 Identities = 93/281 (33%), Positives = 152/281 (54%), Gaps = 2/281 (0%)
 Frame = +2

Query: 906  LSTQDQAAAFMFPPPGVRKIVLATNIAETGITIPDVVFVIDTGRTKENKYHESSQMSSLV 965
            L ++ Q   F   PPG RK+V+ATNIAET +TI  + +V+D G  K+N Y+  + M  L+
Sbjct: 56   LPSEMQTRIFEPAPPGSRKVVIATNIAETSLTINGIYYVVDPGFVKQNVYNSKTGMDQLI 235

Query: 966  ETFVSKASALQRQGRAGRVRDGFCFRLYTRERF-EGFLDYSVPEILRVPLEELCLHIMKC 1024
             T +S+A A QR GRAGR   G C+RLYT   + +  L  +VPEI R  L    L +   
Sbjct: 236  VTPISQAQAKQRAGRAGRTGPGKCYRLYTERAYRDEMLPTNVPEIQRTNLASTVLSLKAM 415

Query: 1025 DLGSPEDFLS-KALDPPQLQVISNAMNLLRKIGACEPNEPKLTPLGQHLAALPVNVKIGK 1083
             +    D L+   +D P +Q + +AM  L  + A + +E  LT LG+ +A  P+   + K
Sbjct: 416  GIN---DLLAFDFMDSPPMQTLISAMEQLHALSALD-DEGLLTRLGRRMAEFPLEPMLSK 583

Query: 1084 MLIFGAIFGCLEPVATLAAVMTEKSPFITPIGRKDEADLAKSSLAVADSDHLTIYNAYLG 1143
            MLI      C + + T+ ++++ ++ F  P  ++  AD  K+     + DHLT+ + Y  
Sbjct: 584  MLIMSVHLACSDEILTIVSMLSVQNVFYRPKDKQALADQKKAKFHQPEGDHLTLLSVYNS 763

Query: 1144 WKKAQQEGGFRSEISYCQRNFLNRTSLLTLEDVKQELMKLV 1184
            WK  +    F S   +C  NF+   +L   +DV+++++ ++
Sbjct: 764  WKNNK----FSS--PWCYENFVQIRTLKRAQDVRKQMLGIM 868
>21806
          Length = 1553

 Score =  147 bits (371), Expect = 3e-35,   Method: Compositional matrix adjust.
 Identities = 91/257 (35%), Positives = 132/257 (51%), Gaps = 2/257 (0%)
 Frame = +2

Query: 63  KIYSFNSANDSGGSANLDKSILKVVINNKLEQRIIGVINEHKKQNSDRGAISGRLSAKKL 122
           K Y+   + + G   N + +I KV I   LE+ ++ +I    +  +  G +S RL++KKL
Sbjct: 185 KTYALPKSEERGHEGNTE-NIEKVHIPAGLEKDLVDLILHEHQHRTRFGVLSKRLTSKKL 361

Query: 123 QDLYMALQAFSFKTKDIEDAMTNTLLHGGDLHSALDWLCLNLSDDALPEGFSQEFE-EQQ 181
            D+Y +L    F  + +E AM+ T+  GGDLH ALDWLCLN  +D LP+GFSQ  + E++
Sbjct: 362 TDIYNSLSTAGFSQRQVEGAMSATVAKGGDLHDALDWLCLNTPNDQLPKGFSQTLQAEEE 541

Query: 182 PKSRPKFQ-SVQIQATLSPPQQTKTKRQXXXXXXXXXXXXXXXXXNMKEWILRYAEQQDX 240
            K++P+F  S Q  A L                             +K+WILRYAE    
Sbjct: 542 RKTKPRFDVSQQHDARLG---PPPAIVPAVPVKETKAPAASAPTGGVKDWILRYAE---- 700

Query: 241 XXXXXXXXXXXXXXXFDPNQRYLNLAARLLDAKEQAAAFKLEKNKQGQKEAQEKIRKFQR 300
                           DPN RYL L+A+L DAK++A   KL  NK G  +A ++IR+   
Sbjct: 701 -----LSSESSGDEQEDPNSRYLKLSAQLEDAKDEATDAKLRGNKPGHTKASKRIRELTL 865

Query: 301 EMETLEDHPIFNPAIKI 317
           E + +E HP FN A K+
Sbjct: 866 ERDAIEKHPHFNXATKL 916

 Score =  146 bits (369), Expect = 5e-35,   Method: Compositional matrix adjust.
 Identities = 68/114 (59%), Positives = 81/114 (71%), Gaps = 1/114 (0%)
 Frame = +2

Query: 361  DVRNFDYTARSWTGKSPKQFLIDWVRKNLPKSPNPSFEKVAVGR-YWKCRVRVVRSEDDV 419
            DVR F+YT + WTGK PKQFLIDW RK+LPKSP P + K+ V    + CRV V + +DDV
Sbjct: 1202 DVRQFEYTRQQWTGKHPKQFLIDWCRKHLPKSPPPKYHKIQVKHNRFXCRVSVEKQKDDV 1381

Query: 420  LVVCPTILTEDGMQAQHLGATLALYRLVKGQSVHQLLPPTYRDVWLEWSDEEKK 473
            L V P IL E   +A+ LG TLALY L +GQSV QLLPP YR VWLEW D+E +
Sbjct: 1382 LSVTPDILCETAKEAEMLGCTLALYHLCRGQSVQQLLPPPYRAVWLEWLDQEAR 1543
>19545
          Length = 519

 Score =  147 bits (370), Expect = 3e-35,   Method: Composition-based stats.
 Identities = 77/155 (49%), Positives = 105/155 (67%), Gaps = 1/155 (0%)
 Frame = +2

Query: 622 CNIVCTQPRRISAVSLATRVCEELGCESGPGGRNSLCGYQIRMESRASES-TRLLYCTTG 680
           CNI+ TQPRRISAVS+A RV EE     G    NS+ GY +R E+        +LYCT G
Sbjct: 14  CNIIVTQPRRISAVSIAERVAEERSEMLG----NSV-GYSVRFETVMPRPYGAMLYCTVG 178

Query: 681 VLLRKLQEDGLLADVSHVIVDEVHERSVQSDFLLVILKEILQKRSDLHLILMSATVDSDK 740
            LLRKL+  G L  VSHVIVDE+HER + +DFLLV+L+++++   DL ++LMSATVD+  
Sbjct: 179 TLLRKLE--GGLRGVSHVIVDEIHERDINTDFLLVLLRDMVRAYPDLRVLLMSATVDTTL 352

Query: 741 FSTYFTHCPILRISGRSYPVEVFHLEDIVEETGFV 775
           F+ YF  C ++ + GR YPV+ ++LED ++   FV
Sbjct: 353 FTDYFGSCTVVEVYGRVYPVQEYYLEDCIQMLNFV 457
>20747
          Length = 444

 Score =  100 bits (249), Expect = 4e-21,   Method: Compositional matrix adjust.
 Identities = 60/145 (41%), Positives = 85/145 (58%), Gaps = 5/145 (3%)
 Frame = +1

Query: 598 SGKSTQVPHFLLEDLLLDECGARKCNIVCTQPRRISAVSLATRVCEELGCESGPGGRNSL 657
           SGK+TQVP FL E     + G     I  T+PRR++A+S++ RV EE+   S        
Sbjct: 1   SGKTTQVPQFLYEAGYAHKGGM----IGVTEPRRVAAISMSQRVAEEMNLTSRE------ 150

Query: 658 CGYQIRMESRASESTRLLYCTTGVLLRKLQEDGLLADVSHVIVDEVHERSVQSDFLLVIL 717
             YQIR E   +  T + + T GVLLR++Q+D +L+  S +I+DE HERSV +D L+ +L
Sbjct: 151 VSYQIRYEGNVTPDTHIKFMTDGVLLREIQQDFVLSKYSVIILDEAHERSVFTDILIGLL 330

Query: 718 KEILQKR-----SDLHLILMSATVD 737
             I   R     S L L++MSAT+D
Sbjct: 331 SRIAPYRIKKNLSPLKLVIMSATLD 405
>18403
          Length = 434

 Score = 95.9 bits (237), Expect = 9e-20,   Method: Composition-based stats.
 Identities = 55/137 (40%), Positives = 80/137 (58%)
 Frame = +2

Query: 991  RLYTRERFEGFLDYSVPEILRVPLEELCLHIMKCDLGSPEDFLSKALDPPQLQVISNAMN 1050
            RLY    +  F  YS PEI RVPL+ L L ++   L +   F    ++PP L  I N++ 
Sbjct: 2    RLYAESDYNEFEAYSTPEIQRVPLDSLVLQLISMGLPNVRKF--PFIEPPDLSTIENSVR 175

Query: 1051 LLRKIGACEPNEPKLTPLGQHLAALPVNVKIGKMLIFGAIFGCLEPVATLAAVMTEKSPF 1110
             L++ GA   +E  LT +GQ L+ LPV+V IGKMLI G+IF  ++P+ ++AA M+ +SPF
Sbjct: 176  FLKEQGALAGDE-SLTAIGQMLSMLPVDVVIGKMLIMGSIFHMVDPILSIAAAMSVQSPF 352

Query: 1111 ITPIGRKDEADLAKSSL 1127
                    +A  A+ SL
Sbjct: 353  TGKAHIDHDAIAARKSL 403
>17966
          Length = 424

 Score = 92.8 bits (229), Expect = 8e-19,   Method: Composition-based stats.
 Identities = 57/138 (41%), Positives = 80/138 (57%)
 Frame = -1

Query: 976  QRQGRAGRVRDGFCFRLYTRERFEGFLDYSVPEILRVPLEELCLHIMKCDLGSPEDFLSK 1035
            QR+GRAGRVR GF   + +R   E    ++  +I   PL EL L I    LG    FLS 
Sbjct: 415  QRRGRAGRVRPGFLSIVQSRPLRETGPAHNSGDIPH-PLHELALSIKLLRLGPISGFLSX 239

Query: 1036 ALDPPQLQVISNAMNLLRKIGACEPNEPKLTPLGQHLAALPVNVKIGKMLIFGAIFGCLE 1095
            A++PP +  +  A   LR + A + N+ +LTPLG+ LA +P+   +GKM+I+G IF   +
Sbjct: 238  AVEPPPIDAVVEAEATLRSMHALDSND-ELTPLGRILARMPIEPHLGKMIIYGCIFYIGD 62

Query: 1096 PVATLAAVMTEKSPFITP 1113
             + T+AA  T   PFITP
Sbjct: 61   AMCTIAASTTFPEPFITP 8
>19948
          Length = 466

 Score = 78.6 bits (192), Expect = 2e-14,   Method: Compositional matrix adjust.
 Identities = 42/108 (38%), Positives = 61/108 (56%)
 Frame = +1

Query: 864 NIEGAVLIFLPGLAHIQQLYDLLSSDRRFYSERYQVIALHSVLSTQDQAAAFMFPPPGVR 923
            I GAVL FLPG + I  +   L     F S +Y ++ LHS +  ++Q   F   P GV 
Sbjct: 124 GIPGAVLFFLPGWSLIFMIQRHLQMSPEFGSSKYCILPLHSQIPREEQRKVFEPVPDGVT 303

Query: 924 KIVLATNIAETGITIPDVVFVIDTGRTKENKYHESSQMSSLVETFVSK 971
           KI+L+TNIAET +TI DVV+VID+ + K   +   + M++    + S 
Sbjct: 304 KIILSTNIAETSVTINDVVYVIDSCKVKMKLFTSHNNMTNYATVWASN 447
>35632
          Length = 627

 Score = 64.7 bits (156), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 44/154 (28%), Positives = 80/154 (51%), Gaps = 13/154 (8%)
 Frame = +1

Query: 1040 PQLQVISNAMNLLRKIGA--CEPN------EPKLTPLGQHLAALPVNVKIGKMLIFGAIF 1091
            P+L  I   +  L+++GA  C+        +  LT +G+ +A LPV+++IGK++I G +F
Sbjct: 19   PELDNIERTILSLKQVGATMCDQQWQVKRFDGDLTFVGRVMADLPVDIRIGKLMILGYVF 198

Query: 1092 GCLEPVATLAAVMTEKSPFITPIGRKDEADLAKSSLAVAD-SDHLTIYNAYLGWKKAQQE 1150
            G LE    + A ++ KS F TP   + EA + K   +    SD   I +AY  W+K ++ 
Sbjct: 199  GLLEECIIIGAALSLKSIFATPFKSRLEAFMHKYQWSSGSLSDCQAILHAYRVWEKCKEL 378

Query: 1151 GGFR----SEISYCQRNFLNRTSLLTLEDVKQEL 1180
              F+    +E  +  ++F+    +  +  + +EL
Sbjct: 379  QEFKRTGMTENQWGMKHFIQTRRINEVHQLVREL 480
>07993
          Length = 408

 Score = 33.5 bits (75), Expect = 0.67,   Method: Composition-based stats.
 Identities = 13/29 (44%), Positives = 18/29 (62%)
 Frame = -2

Query: 984  VRDGFCFRLYTRERFEGFLDYSVPEILRV 1012
            V D FCF L     F   LD++VPE++R+
Sbjct: 284  VLDQFCFGLKINHAFRPLLDHTVPEVIRI 198
>04440
          Length = 883

 Score = 32.0 bits (71), Expect = 1.7,   Method: Composition-based stats.
 Identities = 27/93 (29%), Positives = 45/93 (48%), Gaps = 6/93 (6%)
 Frame = +1

Query: 662 IRMESRASESTRL----LYCTTGVLLRKLQEDGLLADVSHVIVDEVHERSVQSDFLLVIL 717
           I+M++ + E + L    ++C   +  + L+ DG+ AD SH  +  V    + S  L    
Sbjct: 307 IKMQTYSMEVSFLKSYTVFCVLSLFCKVLRRDGICADFSH--LKSVGFVRLGSYSLFYRT 480

Query: 718 KEILQKRS--DLHLILMSATVDSDKFSTYFTHC 748
            + L+ RS  +L  I+ S +V    F  YFT C
Sbjct: 481 VDCLENRSIENLIHIIGSCSVFLKSFCKYFTFC 579
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6755919|ref|NP_035794.1| ubiquitin B [Mus musculus]
         (305 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

04649                                                                 159   2e-39
13455                                                                 157   7e-39
04017                                                                 155   2e-38
00758                                                                 154   3e-38
03942                                                                 153   9e-38
34270                                                                 122   7e-35
08296                                                                  96   1e-20
24173                                                                  85   3e-17
02863                                                                  54   1e-16
25295                                                                  49   3e-06
14135                                                                  48   6e-06
34268                                                                  47   7e-06
13753                                                                  44   1e-04
22667                                                                  37   0.010
>04649
          Length = 1590

 Score =  159 bits (401), Expect = 2e-39,   Method: Compositional matrix adjust.
 Identities = 78/80 (97%), Positives = 78/80 (97%), Gaps = 2/80 (2%)
 Frame = -2

Query: 75  GG--MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTL 132
           GG  MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTL
Sbjct: 461 GGXXMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTL 282

Query: 133 SDYNIQKESTLHLVLRLRGG 152
           SDYNIQKESTLHLVLRLRGG
Sbjct: 281 SDYNIQKESTLHLVLRLRGG 222

 Score =  159 bits (401), Expect = 2e-39,   Method: Compositional matrix adjust.
 Identities = 78/80 (97%), Positives = 78/80 (97%), Gaps = 2/80 (2%)
 Frame = -2

Query: 151 GG--MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTL 208
           GG  MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTL
Sbjct: 461 GGXXMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTL 282

Query: 209 SDYNIQKESTLHLVLRLRGG 228
           SDYNIQKESTLHLVLRLRGG
Sbjct: 281 SDYNIQKESTLHLVLRLRGG 222

 Score =  159 bits (401), Expect = 2e-39,   Method: Compositional matrix adjust.
 Identities = 78/80 (97%), Positives = 78/80 (97%), Gaps = 2/80 (2%)
 Frame = -2

Query: 227 GG--MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTL 284
           GG  MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTL
Sbjct: 461 GGXXMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTL 282

Query: 285 SDYNIQKESTLHLVLRLRGG 304
           SDYNIQKESTLHLVLRLRGG
Sbjct: 281 SDYNIQKESTLHLVLRLRGG 222

 Score =  159 bits (401), Expect = 2e-39,   Method: Compositional matrix adjust.
 Identities = 76/76 (100%), Positives = 76/76 (100%)
 Frame = -2

Query: 1   MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYN 60
           MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYN
Sbjct: 449 MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYN 270

Query: 61  IQKESTLHLVLRLRGG 76
           IQKESTLHLVLRLRGG
Sbjct: 269 IQKESTLHLVLRLRGG 222
>13455
          Length = 809

 Score =  157 bits (396), Expect = 7e-39,   Method: Compositional matrix adjust.
 Identities = 76/79 (96%), Positives = 77/79 (97%)
 Frame = +3

Query: 75  GGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSD 134
             MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSD
Sbjct: 351 ASMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSD 530

Query: 135 YNIQKESTLHLVLRLRGGM 153
           YNIQKESTLHLVLRLRGG+
Sbjct: 531 YNIQKESTLHLVLRLRGGI 587

 Score =  157 bits (396), Expect = 7e-39,   Method: Compositional matrix adjust.
 Identities = 76/79 (96%), Positives = 77/79 (97%)
 Frame = +3

Query: 151 GGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSD 210
             MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSD
Sbjct: 351 ASMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSD 530

Query: 211 YNIQKESTLHLVLRLRGGM 229
           YNIQKESTLHLVLRLRGG+
Sbjct: 531 YNIQKESTLHLVLRLRGGI 587

 Score =  156 bits (395), Expect = 9e-39,   Method: Compositional matrix adjust.
 Identities = 76/78 (97%), Positives = 76/78 (97%)
 Frame = +3

Query: 227 GGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSD 286
             MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSD
Sbjct: 351 ASMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSD 530

Query: 287 YNIQKESTLHLVLRLRGG 304
           YNIQKESTLHLVLRLRGG
Sbjct: 531 YNIQKESTLHLVLRLRGG 584

 Score =  156 bits (395), Expect = 1e-38,   Method: Compositional matrix adjust.
 Identities = 76/77 (98%), Positives = 77/77 (100%)
 Frame = +3

Query: 1   MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYN 60
           MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYN
Sbjct: 357 MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYN 536

Query: 61  IQKESTLHLVLRLRGGM 77
           IQKESTLHLVLRLRGG+
Sbjct: 537 IQKESTLHLVLRLRGGI 587
>04017
          Length = 690

 Score =  155 bits (392), Expect = 2e-38,   Method: Compositional matrix adjust.
 Identities = 76/78 (97%), Positives = 77/78 (98%)
 Frame = -1

Query: 1   MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYN 60
           MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYN
Sbjct: 342 MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYN 163

Query: 61  IQKESTLHLVLRLRGGMQ 78
           IQKESTLHLVLRLRGG +
Sbjct: 162 IQKESTLHLVLRLRGGAK 109

 Score =  155 bits (392), Expect = 2e-38,   Method: Compositional matrix adjust.
 Identities = 76/78 (97%), Positives = 77/78 (98%)
 Frame = -1

Query: 77  MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYN 136
           MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYN
Sbjct: 342 MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYN 163

Query: 137 IQKESTLHLVLRLRGGMQ 154
           IQKESTLHLVLRLRGG +
Sbjct: 162 IQKESTLHLVLRLRGGAK 109

 Score =  155 bits (392), Expect = 2e-38,   Method: Compositional matrix adjust.
 Identities = 76/78 (97%), Positives = 77/78 (98%)
 Frame = -1

Query: 153 MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYN 212
           MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYN
Sbjct: 342 MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYN 163

Query: 213 IQKESTLHLVLRLRGGMQ 230
           IQKESTLHLVLRLRGG +
Sbjct: 162 IQKESTLHLVLRLRGGAK 109

 Score =  155 bits (392), Expect = 2e-38,   Method: Compositional matrix adjust.
 Identities = 76/76 (100%), Positives = 76/76 (100%)
 Frame = -1

Query: 229 MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYN 288
           MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYN
Sbjct: 342 MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYN 163

Query: 289 IQKESTLHLVLRLRGG 304
           IQKESTLHLVLRLRGG
Sbjct: 162 IQKESTLHLVLRLRGG 115
>00758
          Length = 1050

 Score =  154 bits (390), Expect = 3e-38,   Method: Compositional matrix adjust.
 Identities = 76/76 (100%), Positives = 76/76 (100%)
 Frame = +1

Query: 1   MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYN 60
           MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYN
Sbjct: 523 MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYN 702

Query: 61  IQKESTLHLVLRLRGG 76
           IQKESTLHLVLRLRGG
Sbjct: 703 IQKESTLHLVLRLRGG 750

 Score =  154 bits (390), Expect = 3e-38,   Method: Compositional matrix adjust.
 Identities = 76/76 (100%), Positives = 76/76 (100%)
 Frame = +1

Query: 77  MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYN 136
           MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYN
Sbjct: 523 MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYN 702

Query: 137 IQKESTLHLVLRLRGG 152
           IQKESTLHLVLRLRGG
Sbjct: 703 IQKESTLHLVLRLRGG 750

 Score =  154 bits (390), Expect = 3e-38,   Method: Compositional matrix adjust.
 Identities = 76/76 (100%), Positives = 76/76 (100%)
 Frame = +1

Query: 153 MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYN 212
           MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYN
Sbjct: 523 MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYN 702

Query: 213 IQKESTLHLVLRLRGG 228
           IQKESTLHLVLRLRGG
Sbjct: 703 IQKESTLHLVLRLRGG 750

 Score =  154 bits (390), Expect = 3e-38,   Method: Compositional matrix adjust.
 Identities = 76/76 (100%), Positives = 76/76 (100%)
 Frame = +1

Query: 229 MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYN 288
           MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYN
Sbjct: 523 MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYN 702

Query: 289 IQKESTLHLVLRLRGG 304
           IQKESTLHLVLRLRGG
Sbjct: 703 IQKESTLHLVLRLRGG 750
>03942
          Length = 912

 Score =  153 bits (386), Expect = 9e-38,   Method: Compositional matrix adjust.
 Identities = 77/81 (95%), Positives = 78/81 (96%), Gaps = 1/81 (1%)
 Frame = +1

Query: 73  LRGG-MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRT 131
            RGG MQIFVKTLTGKTITLEVEPSDTIENVKAK +DKEGIPPDQQRLIFAGKQLEDGRT
Sbjct: 391 CRGGIMQIFVKTLTGKTITLEVEPSDTIENVKAKSKDKEGIPPDQQRLIFAGKQLEDGRT 570

Query: 132 LSDYNIQKESTLHLVLRLRGG 152
           LSDYNIQKESTLHLVLRLRGG
Sbjct: 571 LSDYNIQKESTLHLVLRLRGG 633

 Score =  153 bits (386), Expect = 9e-38,   Method: Compositional matrix adjust.
 Identities = 77/81 (95%), Positives = 78/81 (96%), Gaps = 1/81 (1%)
 Frame = +1

Query: 149 LRGG-MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRT 207
            RGG MQIFVKTLTGKTITLEVEPSDTIENVKAK +DKEGIPPDQQRLIFAGKQLEDGRT
Sbjct: 391 CRGGIMQIFVKTLTGKTITLEVEPSDTIENVKAKSKDKEGIPPDQQRLIFAGKQLEDGRT 570

Query: 208 LSDYNIQKESTLHLVLRLRGG 228
           LSDYNIQKESTLHLVLRLRGG
Sbjct: 571 LSDYNIQKESTLHLVLRLRGG 633

 Score =  153 bits (386), Expect = 9e-38,   Method: Compositional matrix adjust.
 Identities = 77/81 (95%), Positives = 78/81 (96%), Gaps = 1/81 (1%)
 Frame = +1

Query: 225 LRGG-MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRT 283
            RGG MQIFVKTLTGKTITLEVEPSDTIENVKAK +DKEGIPPDQQRLIFAGKQLEDGRT
Sbjct: 391 CRGGIMQIFVKTLTGKTITLEVEPSDTIENVKAKSKDKEGIPPDQQRLIFAGKQLEDGRT 570

Query: 284 LSDYNIQKESTLHLVLRLRGG 304
           LSDYNIQKESTLHLVLRLRGG
Sbjct: 571 LSDYNIQKESTLHLVLRLRGG 633

 Score =  150 bits (380), Expect = 5e-37,   Method: Compositional matrix adjust.
 Identities = 74/76 (97%), Positives = 75/76 (98%)
 Frame = +1

Query: 1   MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYN 60
           MQIFVKTLTGKTITLEVEPSDTIENVKAK +DKEGIPPDQQRLIFAGKQLEDGRTLSDYN
Sbjct: 406 MQIFVKTLTGKTITLEVEPSDTIENVKAKSKDKEGIPPDQQRLIFAGKQLEDGRTLSDYN 585

Query: 61  IQKESTLHLVLRLRGG 76
           IQKESTLHLVLRLRGG
Sbjct: 586 IQKESTLHLVLRLRGG 633
>34270
          Length = 274

 Score =  122 bits (305), Expect(3) = 7e-35,   Method: Compositional matrix adjust.
 Identities = 59/59 (100%), Positives = 59/59 (100%)
 Frame = +1

Query: 83  TLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKES 141
           TLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKES
Sbjct: 52  TLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKES 228

 Score =  122 bits (305), Expect(3) = 7e-35,   Method: Compositional matrix adjust.
 Identities = 59/59 (100%), Positives = 59/59 (100%)
 Frame = +1

Query: 159 TLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKES 217
           TLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKES
Sbjct: 52  TLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKES 228

 Score = 35.4 bits (80), Expect(3) = 7e-35,   Method: Composition-based stats.
 Identities = 16/16 (100%), Positives = 16/16 (100%)
 Frame = +3

Query: 67 LHLVLRLRGGMQIFVK 82
          LHLVLRLRGGMQIFVK
Sbjct: 3  LHLVLRLRGGMQIFVK 50

 Score = 35.4 bits (80), Expect(3) = 7e-35,   Method: Composition-based stats.
 Identities = 16/16 (100%), Positives = 16/16 (100%)
 Frame = +3

Query: 143 LHLVLRLRGGMQIFVK 158
           LHLVLRLRGGMQIFVK
Sbjct: 3   LHLVLRLRGGMQIFVK 50

 Score = 27.7 bits (60), Expect(3) = 7e-35,   Method: Compositional matrix adjust.
 Identities = 12/17 (70%), Positives = 14/17 (82%)
 Frame = +2

Query: 138 QKESTLHLVLRLRGGMQ 154
           +K  TLHLVLRLRGG +
Sbjct: 218 RKSPTLHLVLRLRGGAK 268

 Score = 27.7 bits (60), Expect(3) = 7e-35,   Method: Compositional matrix adjust.
 Identities = 12/17 (70%), Positives = 14/17 (82%)
 Frame = +2

Query: 214 QKESTLHLVLRLRGGMQ 230
           +K  TLHLVLRLRGG +
Sbjct: 218 RKSPTLHLVLRLRGGAK 268

 Score =  122 bits (305), Expect(3) = 8e-35,   Method: Compositional matrix adjust.
 Identities = 59/59 (100%), Positives = 59/59 (100%)
 Frame = +1

Query: 235 TLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKES 293
           TLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKES
Sbjct: 52  TLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKES 228

 Score = 35.4 bits (80), Expect(3) = 8e-35,   Method: Composition-based stats.
 Identities = 16/16 (100%), Positives = 16/16 (100%)
 Frame = +3

Query: 219 LHLVLRLRGGMQIFVK 234
           LHLVLRLRGGMQIFVK
Sbjct: 3   LHLVLRLRGGMQIFVK 50

 Score = 27.7 bits (60), Expect(3) = 8e-35,   Method: Compositional matrix adjust.
 Identities = 12/15 (80%), Positives = 13/15 (86%)
 Frame = +2

Query: 290 QKESTLHLVLRLRGG 304
           +K  TLHLVLRLRGG
Sbjct: 218 RKSPTLHLVLRLRGG 262

 Score =  122 bits (305), Expect(2) = 2e-30,   Method: Compositional matrix adjust.
 Identities = 59/59 (100%), Positives = 59/59 (100%)
 Frame = +1

Query: 7   TLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKES 65
           TLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKES
Sbjct: 52  TLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKES 228

 Score = 27.7 bits (60), Expect(2) = 2e-30,   Method: Compositional matrix adjust.
 Identities = 12/17 (70%), Positives = 14/17 (82%)
 Frame = +2

Query: 62  QKESTLHLVLRLRGGMQ 78
           +K  TLHLVLRLRGG +
Sbjct: 218 RKSPTLHLVLRLRGGAK 268
>08296
          Length = 897

 Score = 96.3 bits (238), Expect = 1e-20,   Method: Compositional matrix adjust.
 Identities = 45/85 (52%), Positives = 62/85 (72%)
 Frame = +1

Query: 69  LVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLED 128
           ++ R    M I VKTLTGK I +++EP+D +E +K ++++KEGIPP QQRLIF+GKQ+ D
Sbjct: 103 VIBRXYNKMLIKVKTLTGKEIEIDIEPTDKVERIKERVEEKEGIPPQQQRLIFSGKQMND 282

Query: 129 GRTLSDYNIQKESTLHLVLRLRGGM 153
            +T  DY +   S LHLVL LRGG+
Sbjct: 283 EKTAQDYKVIGGSVLHLVLALRGGL 357

 Score = 96.3 bits (238), Expect = 1e-20,   Method: Compositional matrix adjust.
 Identities = 45/85 (52%), Positives = 62/85 (72%)
 Frame = +1

Query: 145 LVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLED 204
           ++ R    M I VKTLTGK I +++EP+D +E +K ++++KEGIPP QQRLIF+GKQ+ D
Sbjct: 103 VIBRXYNKMLIKVKTLTGKEIEIDIEPTDKVERIKERVEEKEGIPPQQQRLIFSGKQMND 282

Query: 205 GRTLSDYNIQKESTLHLVLRLRGGM 229
            +T  DY +   S LHLVL LRGG+
Sbjct: 283 EKTAQDYKVIGGSVLHLVLALRGGL 357

 Score = 95.5 bits (236), Expect = 2e-20,   Method: Compositional matrix adjust.
 Identities = 45/84 (53%), Positives = 61/84 (72%)
 Frame = +1

Query: 221 LVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLED 280
           ++ R    M I VKTLTGK I +++EP+D +E +K ++++KEGIPP QQRLIF+GKQ+ D
Sbjct: 103 VIBRXYNKMLIKVKTLTGKEIEIDIEPTDKVERIKERVEEKEGIPPQQQRLIFSGKQMND 282

Query: 281 GRTLSDYNIQKESTLHLVLRLRGG 304
            +T  DY +   S LHLVL LRGG
Sbjct: 283 EKTAQDYKVIGGSVLHLVLALRGG 354

 Score = 95.1 bits (235), Expect = 3e-20,   Method: Compositional matrix adjust.
 Identities = 44/77 (57%), Positives = 59/77 (76%)
 Frame = +1

Query: 1   MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYN 60
           M I VKTLTGK I +++EP+D +E +K ++++KEGIPP QQRLIF+GKQ+ D +T  DY 
Sbjct: 127 MLIKVKTLTGKEIEIDIEPTDKVERIKERVEEKEGIPPQQQRLIFSGKQMNDEKTAQDYK 306

Query: 61  IQKESTLHLVLRLRGGM 77
           +   S LHLVL LRGG+
Sbjct: 307 VIGGSVLHLVLALRGGL 357
>24173
          Length = 413

 Score = 85.1 bits (209), Expect = 3e-17,   Method: Compositional matrix adjust.
 Identities = 44/77 (57%), Positives = 55/77 (71%), Gaps = 1/77 (1%)
 Frame = -2

Query: 76  GMQIFVKTLTGKTIT-LEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSD 134
              + +KTLT +  + L  E   T+  +K +I DK+GI P+QQRL+FAGKQLEDGR LSD
Sbjct: 352 AFSLNLKTLTRQERSALTWEGGVTVGELKCQIYDKDGISPEQQRLVFAGKQLEDGRLLSD 173

Query: 135 YNIQKESTLHLVLRLRG 151
           YNI  +STLHLV RLRG
Sbjct: 172 YNITDDSTLHLVFRLRG 122

 Score = 85.1 bits (209), Expect = 3e-17,   Method: Compositional matrix adjust.
 Identities = 44/77 (57%), Positives = 55/77 (71%), Gaps = 1/77 (1%)
 Frame = -2

Query: 152 GMQIFVKTLTGKTIT-LEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSD 210
              + +KTLT +  + L  E   T+  +K +I DK+GI P+QQRL+FAGKQLEDGR LSD
Sbjct: 352 AFSLNLKTLTRQERSALTWEGGVTVGELKCQIYDKDGISPEQQRLVFAGKQLEDGRLLSD 173

Query: 211 YNIQKESTLHLVLRLRG 227
           YNI  +STLHLV RLRG
Sbjct: 172 YNITDDSTLHLVFRLRG 122

 Score = 85.1 bits (209), Expect = 3e-17,   Method: Compositional matrix adjust.
 Identities = 44/77 (57%), Positives = 55/77 (71%), Gaps = 1/77 (1%)
 Frame = -2

Query: 228 GMQIFVKTLTGKTIT-LEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSD 286
              + +KTLT +  + L  E   T+  +K +I DK+GI P+QQRL+FAGKQLEDGR LSD
Sbjct: 352 AFSLNLKTLTRQERSALTWEGGVTVGELKCQIYDKDGISPEQQRLVFAGKQLEDGRLLSD 173

Query: 287 YNIQKESTLHLVLRLRG 303
           YNI  +STLHLV RLRG
Sbjct: 172 YNITDDSTLHLVFRLRG 122

 Score = 85.1 bits (209), Expect = 4e-17,   Method: Compositional matrix adjust.
 Identities = 44/72 (61%), Positives = 54/72 (75%), Gaps = 1/72 (1%)
 Frame = -2

Query: 5   VKTLTGKTIT-LEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQK 63
           +KTLT +  + L  E   T+  +K +I DK+GI P+QQRL+FAGKQLEDGR LSDYNI  
Sbjct: 337 LKTLTRQERSALTWEGGVTVGELKCQIYDKDGISPEQQRLVFAGKQLEDGRLLSDYNITD 158

Query: 64  ESTLHLVLRLRG 75
           +STLHLV RLRG
Sbjct: 157 DSTLHLVFRLRG 122
>02863
          Length = 583

 Score = 53.9 bits (128), Expect(2) = 1e-16,   Method: Compositional matrix adjust.
 Identities = 25/51 (49%), Positives = 34/51 (66%)
 Frame = +1

Query: 76  GMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQL 126
              + +KTLTGKT+ L  E   T+  +K +I DK+GI P+QQRL+FAGK  
Sbjct: 310 AFSLNLKTLTGKTVALTGEGGMTVGELKCQIYDKDGISPEQQRLVFAGKHW 462

 Score = 53.9 bits (128), Expect(2) = 1e-16,   Method: Compositional matrix adjust.
 Identities = 25/51 (49%), Positives = 34/51 (66%)
 Frame = +1

Query: 152 GMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQL 202
              + +KTLTGKT+ L  E   T+  +K +I DK+GI P+QQRL+FAGK  
Sbjct: 310 AFSLNLKTLTGKTVALTGEGGMTVGELKCQIYDKDGISPEQQRLVFAGKHW 462

 Score = 53.9 bits (128), Expect(2) = 1e-16,   Method: Compositional matrix adjust.
 Identities = 25/51 (49%), Positives = 34/51 (66%)
 Frame = +1

Query: 228 GMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQL 278
              + +KTLTGKT+ L  E   T+  +K +I DK+GI P+QQRL+FAGK  
Sbjct: 310 AFSLNLKTLTGKTVALTGEGGMTVGELKCQIYDKDGISPEQQRLVFAGKHW 462

 Score = 49.3 bits (116), Expect(2) = 1e-16,   Method: Compositional matrix adjust.
 Identities = 23/30 (76%), Positives = 24/30 (80%)
 Frame = +3

Query: 122 AGKQLEDGRTLSDYNIQKESTLHLVLRLRG 151
             K LEDGR LSDYNI  +STLHLVLRLRG
Sbjct: 447 CWKTLEDGRLLSDYNITDDSTLHLVLRLRG 536

 Score = 49.3 bits (116), Expect(2) = 1e-16,   Method: Compositional matrix adjust.
 Identities = 23/30 (76%), Positives = 24/30 (80%)
 Frame = +3

Query: 198 AGKQLEDGRTLSDYNIQKESTLHLVLRLRG 227
             K LEDGR LSDYNI  +STLHLVLRLRG
Sbjct: 447 CWKTLEDGRLLSDYNITDDSTLHLVLRLRG 536

 Score = 49.3 bits (116), Expect(2) = 1e-16,   Method: Compositional matrix adjust.
 Identities = 23/30 (76%), Positives = 24/30 (80%)
 Frame = +3

Query: 274 AGKQLEDGRTLSDYNIQKESTLHLVLRLRG 303
             K LEDGR LSDYNI  +STLHLVLRLRG
Sbjct: 447 CWKTLEDGRLLSDYNITDDSTLHLVLRLRG 536

 Score = 53.9 bits (128), Expect(2) = 1e-16,   Method: Compositional matrix adjust.
 Identities = 25/46 (54%), Positives = 33/46 (71%)
 Frame = +1

Query: 5   VKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQL 50
           +KTLTGKT+ L  E   T+  +K +I DK+GI P+QQRL+FAGK  
Sbjct: 325 LKTLTGKTVALTGEGGMTVGELKCQIYDKDGISPEQQRLVFAGKHW 462

 Score = 49.3 bits (116), Expect(2) = 1e-16,   Method: Compositional matrix adjust.
 Identities = 23/30 (76%), Positives = 24/30 (80%)
 Frame = +3

Query: 46  AGKQLEDGRTLSDYNIQKESTLHLVLRLRG 75
             K LEDGR LSDYNI  +STLHLVLRLRG
Sbjct: 447 CWKTLEDGRLLSDYNITDDSTLHLVLRLRG 536
>25295
          Length = 998

 Score = 48.5 bits (114), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 24/69 (34%), Positives = 42/69 (60%)
 Frame = -2

Query: 8   LTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTL 67
           L G+T+   +  +DTI  +KAK+ +  G+P  +Q+L + G  ++D  TL+ YN    +T+
Sbjct: 964 LNGQTLEFSLPLTDTISVLKAKLNEVLGMPAGKQKLQYEGIFVKDSNTLAFYNFMMGATV 785

Query: 68  HLVLRLRGG 76
            L ++ RGG
Sbjct: 784 QLQMKERGG 758

 Score = 48.5 bits (114), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 24/69 (34%), Positives = 42/69 (60%)
 Frame = -2

Query: 84  LTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTL 143
           L G+T+   +  +DTI  +KAK+ +  G+P  +Q+L + G  ++D  TL+ YN    +T+
Sbjct: 964 LNGQTLEFSLPLTDTISVLKAKLNEVLGMPAGKQKLQYEGIFVKDSNTLAFYNFMMGATV 785

Query: 144 HLVLRLRGG 152
            L ++ RGG
Sbjct: 784 QLQMKERGG 758

 Score = 48.5 bits (114), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 24/69 (34%), Positives = 42/69 (60%)
 Frame = -2

Query: 160 LTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTL 219
           L G+T+   +  +DTI  +KAK+ +  G+P  +Q+L + G  ++D  TL+ YN    +T+
Sbjct: 964 LNGQTLEFSLPLTDTISVLKAKLNEVLGMPAGKQKLQYEGIFVKDSNTLAFYNFMMGATV 785

Query: 220 HLVLRLRGG 228
            L ++ RGG
Sbjct: 784 QLQMKERGG 758

 Score = 48.5 bits (114), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 24/69 (34%), Positives = 42/69 (60%)
 Frame = -2

Query: 236 LTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTL 295
           L G+T+   +  +DTI  +KAK+ +  G+P  +Q+L + G  ++D  TL+ YN    +T+
Sbjct: 964 LNGQTLEFSLPLTDTISVLKAKLNEVLGMPAGKQKLQYEGIFVKDSNTLAFYNFMMGATV 785

Query: 296 HLVLRLRGG 304
            L ++ RGG
Sbjct: 784 QLQMKERGG 758
>14135
          Length = 567

 Score = 47.8 bits (112), Expect = 6e-06,   Method: Compositional matrix adjust.
 Identities = 24/69 (34%), Positives = 42/69 (60%)
 Frame = +2

Query: 8   LTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTL 67
           L G+T+   +  +DTI  +KAK+ +  G+P  +Q+L + G  ++D  TL+ YN    +T+
Sbjct: 185 LNGQTLEFSLPLTDTISVLKAKLNEVLGMPAGKQKLQYEGIFVKDSNTLAFYNFMMGATV 364

Query: 68  HLVLRLRGG 76
            L ++ RGG
Sbjct: 365 QLQMKERGG 391

 Score = 47.8 bits (112), Expect = 6e-06,   Method: Compositional matrix adjust.
 Identities = 24/69 (34%), Positives = 42/69 (60%)
 Frame = +2

Query: 84  LTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTL 143
           L G+T+   +  +DTI  +KAK+ +  G+P  +Q+L + G  ++D  TL+ YN    +T+
Sbjct: 185 LNGQTLEFSLPLTDTISVLKAKLNEVLGMPAGKQKLQYEGIFVKDSNTLAFYNFMMGATV 364

Query: 144 HLVLRLRGG 152
            L ++ RGG
Sbjct: 365 QLQMKERGG 391

 Score = 47.8 bits (112), Expect = 6e-06,   Method: Compositional matrix adjust.
 Identities = 24/69 (34%), Positives = 42/69 (60%)
 Frame = +2

Query: 160 LTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTL 219
           L G+T+   +  +DTI  +KAK+ +  G+P  +Q+L + G  ++D  TL+ YN    +T+
Sbjct: 185 LNGQTLEFSLPLTDTISVLKAKLNEVLGMPAGKQKLQYEGIFVKDSNTLAFYNFMMGATV 364

Query: 220 HLVLRLRGG 228
            L ++ RGG
Sbjct: 365 QLQMKERGG 391

 Score = 47.8 bits (112), Expect = 6e-06,   Method: Compositional matrix adjust.
 Identities = 24/69 (34%), Positives = 42/69 (60%)
 Frame = +2

Query: 236 LTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTL 295
           L G+T+   +  +DTI  +KAK+ +  G+P  +Q+L + G  ++D  TL+ YN    +T+
Sbjct: 185 LNGQTLEFSLPLTDTISVLKAKLNEVLGMPAGKQKLQYEGIFVKDSNTLAFYNFMMGATV 364

Query: 296 HLVLRLRGG 304
            L ++ RGG
Sbjct: 365 QLQMKERGG 391
>34268
          Length = 463

 Score = 47.4 bits (111), Expect = 7e-06,   Method: Compositional matrix adjust.
 Identities = 23/25 (92%), Positives = 23/25 (92%)
 Frame = -2

Query: 1  MQIFVKTLTGKTITLEVEPSDTIEN 25
          MQIFVKTLT KTITLEVEP DTIEN
Sbjct: 96 MQIFVKTLTCKTITLEVEPMDTIEN 22

 Score = 47.4 bits (111), Expect = 7e-06,   Method: Compositional matrix adjust.
 Identities = 23/25 (92%), Positives = 23/25 (92%)
 Frame = -2

Query: 77  MQIFVKTLTGKTITLEVEPSDTIEN 101
           MQIFVKTLT KTITLEVEP DTIEN
Sbjct: 96  MQIFVKTLTCKTITLEVEPMDTIEN 22

 Score = 47.4 bits (111), Expect = 7e-06,   Method: Compositional matrix adjust.
 Identities = 23/25 (92%), Positives = 23/25 (92%)
 Frame = -2

Query: 153 MQIFVKTLTGKTITLEVEPSDTIEN 177
           MQIFVKTLT KTITLEVEP DTIEN
Sbjct: 96  MQIFVKTLTCKTITLEVEPMDTIEN 22

 Score = 47.4 bits (111), Expect = 7e-06,   Method: Compositional matrix adjust.
 Identities = 23/25 (92%), Positives = 23/25 (92%)
 Frame = -2

Query: 229 MQIFVKTLTGKTITLEVEPSDTIEN 253
           MQIFVKTLT KTITLEVEP DTIEN
Sbjct: 96  MQIFVKTLTCKTITLEVEPMDTIEN 22
>13753
          Length = 812

 Score = 43.5 bits (101), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 26/76 (34%), Positives = 44/76 (57%)
 Frame = -3

Query: 1   MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYN 60
           MQ+FV     +  T+ VE ++T+E+VKA ++++E +  +   + F G  LED   LS   
Sbjct: 498 MQLFVHAQ--QIYTIGVEGAETVEDVKALVEERENVSAEDMAVYFGGSPLEDDVCLS--T 331

Query: 61  IQKESTLHLVLRLRGG 76
           ++  STL +  R+ GG
Sbjct: 330 LEDLSTLQVEQRMLGG 283

 Score = 43.1 bits (100), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 26/76 (34%), Positives = 44/76 (57%)
 Frame = -3

Query: 77  MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYN 136
           MQ+FV     +  T+ VE ++T+E+VKA ++++E +  +   + F G  LED   LS   
Sbjct: 498 MQLFVHAQ--QIYTIGVEGAETVEDVKALVEERENVSAEDMAVYFGGSPLEDDVCLS--T 331

Query: 137 IQKESTLHLVLRLRGG 152
           ++  STL +  R+ GG
Sbjct: 330 LEDLSTLQVEQRMLGG 283

 Score = 43.1 bits (100), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 26/76 (34%), Positives = 44/76 (57%)
 Frame = -3

Query: 153 MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYN 212
           MQ+FV     +  T+ VE ++T+E+VKA ++++E +  +   + F G  LED   LS   
Sbjct: 498 MQLFVHAQ--QIYTIGVEGAETVEDVKALVEERENVSAEDMAVYFGGSPLEDDVCLS--T 331

Query: 213 IQKESTLHLVLRLRGG 228
           ++  STL +  R+ GG
Sbjct: 330 LEDLSTLQVEQRMLGG 283

 Score = 43.1 bits (100), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 26/76 (34%), Positives = 44/76 (57%)
 Frame = -3

Query: 229 MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYN 288
           MQ+FV     +  T+ VE ++T+E+VKA ++++E +  +   + F G  LED   LS   
Sbjct: 498 MQLFVHAQ--QIYTIGVEGAETVEDVKALVEERENVSAEDMAVYFGGSPLEDDVCLS--T 331

Query: 289 IQKESTLHLVLRLRGG 304
           ++  STL +  R+ GG
Sbjct: 330 LEDLSTLQVEQRMLGG 283
>22667
          Length = 1002

 Score = 37.0 bits (84), Expect = 0.010,   Method: Compositional matrix adjust.
 Identities = 16/18 (88%), Positives = 18/18 (100%)
 Frame = +3

Query: 61  IQKESTLHLVLRLRGGMQ 78
           IQKESTLHLVLRLRGG++
Sbjct: 450 IQKESTLHLVLRLRGGIK 503

 Score = 37.0 bits (84), Expect = 0.010,   Method: Compositional matrix adjust.
 Identities = 16/18 (88%), Positives = 18/18 (100%)
 Frame = +3

Query: 137 IQKESTLHLVLRLRGGMQ 154
           IQKESTLHLVLRLRGG++
Sbjct: 450 IQKESTLHLVLRLRGGIK 503

 Score = 37.0 bits (84), Expect = 0.010,   Method: Compositional matrix adjust.
 Identities = 16/18 (88%), Positives = 18/18 (100%)
 Frame = +3

Query: 213 IQKESTLHLVLRLRGGMQ 230
           IQKESTLHLVLRLRGG++
Sbjct: 450 IQKESTLHLVLRLRGGIK 503

 Score = 35.0 bits (79), Expect = 0.034,   Method: Compositional matrix adjust.
 Identities = 16/16 (100%), Positives = 16/16 (100%)
 Frame = +3

Query: 289 IQKESTLHLVLRLRGG 304
           IQKESTLHLVLRLRGG
Sbjct: 450 IQKESTLHLVLRLRGG 497
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|8394347|ref|NP_058562.1| serine/threonine kinase 39,
STE20/SPS1 homolog [Mus musculus]
         (556 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

12721                                                                 160   2e-39
13212                                                                 160   2e-39
18921                                                                 158   6e-39
14420                                                                 143   2e-34
13592                                                                 113   2e-25
00300                                                                 112   3e-25
19094                                                                 109   3e-24
09606                                                                 101   1e-21
06405                                                                  93   4e-19
09007                                                                  88   8e-18
30755                                                                  87   2e-17
01707                                                                  86   4e-17
21808                                                                  85   8e-17
37602                                                                  84   2e-16
03240                                                                  82   5e-16
18484                                                                  82   7e-16
14126                                                                  81   1e-15
01718                                                                  81   1e-15
00392                                                                  80   2e-15
15910                                                                  80   3e-15
17975                                                                  78   1e-14
01756                                                                  77   1e-14
26560                                                                  77   2e-14
04852                                                                  76   3e-14
01060                                                                  75   5e-14
31885                                                                  74   1e-13
21079                                                                  73   4e-13
27405                                                                  71   9e-13
01392                                                                  71   1e-12
07291                                                                  70   2e-12
14116                                                                  70   2e-12
11780                                                                  69   7e-12
00715                                                                  67   3e-11
28638                                                                  49   6e-11
07940                                                                  65   8e-11
13066                                                                  65   9e-11
04591                                                                  64   2e-10
01966                                                                  64   2e-10
12672                                                                  63   4e-10
19301                                                                  62   4e-10
29581                                                                  62   6e-10
27546                                                                  62   9e-10
19761                                                                  61   1e-09
28157                                                                  59   5e-09
04138                                                                  57   2e-08
14477                                                                  56   4e-08
03508                                                                  56   4e-08
07836                                                                  55   6e-08
07833                                                                  54   1e-07
21210                                                                  54   2e-07
21433                                                                  53   4e-07
17300                                                                  52   7e-07
11185                                                                  52   7e-07
17253                                                                  51   1e-06
12786                                                                  50   2e-06
18996                                                                  50   3e-06
02638                                                                  49   7e-06
25019                                                                  45   6e-05
20640                                                                  45   7e-05
37063                                                                  44   1e-04
16708                                                                  43   3e-04
17516                                                                  42   0.001
18663                                                                  41   0.001
29590                                                                  40   0.002
31489                                                                  37   0.017
38560                                                                  37   0.023
21800                                                                  37   0.023
18481                                                                  37   0.028
11404                                                                  35   0.093
26009                                                                  35   0.10 
32359                                                                  34   0.15 
01106                                                                  34   0.15 
17637                                                                  34   0.16 
11541                                                                  34   0.17 
32000                                                                  33   0.29 
11342                                                                  32   0.60 
32957                                                                  32   0.64 
13305                                                                  31   1.0  
16350                                                                  31   1.3  
03106                                                                  29   3.9  
05356                                                                  28   8.0  
>12721
          Length = 821

 Score =  160 bits (404), Expect = 2e-39,   Method: Compositional matrix adjust.
 Identities = 91/261 (34%), Positives = 142/261 (54%), Gaps = 1/261 (0%)
 Frame = +1

Query: 81  IGSGATAVVQAALCKPRQERVAIKRINLEKCQTSMDELLKEIQAMSQCSHPNVVTYYTSF 140
           IG G+T +V  A  +  ++ +A+K+++L K Q   + L  E+  M    HPN+V  Y S+
Sbjct: 112 IGEGSTGIVCIATSRDGRQ-MAVKKMDLRK-QQRRELLFNEVVVMRDYHHPNIVEMYNSY 285

Query: 141 VVKDELWLVMKLLSGGSMLDIIKYIVNRGEHKNGVLEEAIIATILKEVLEGLDYLHRNGQ 200
           +V DELW+VM+ + GG++ DI+          N  ++E  IAT+ +  L+ L +LH NG 
Sbjct: 286 LVNDELWVVMEFMEGGALTDIVT---------NNRMDEVQIATVCRACLKALAFLHANGV 438

Query: 201 IHRDLKAGNILLGEDGSVQIADFGVSAFLATGGDVTRN-KVRKTFVGTPCWMAPEVMEQV 259
           IHRD+K+ +ILL  DG V++ DFG  A       VT++ + RK+ VGTP WMAPEV+ ++
Sbjct: 439 IHRDIKSDSILLSHDGKVKLXDFGFCA------QVTQDLQKRKSLVGTPYWMAPEVISRL 600

Query: 260 RGYDFKADMWSFGITAIELATGAAPYHKYPPMKVLMLTLQNDPPTLETGVEDKEMMKKYG 319
             Y  + D+WS GI  +E+     P+   PP++ +       PP L           K  
Sbjct: 601 -PYGPEVDIWSLGIMVMEMIDAEPPFFNEPPLQAMRRIRDMPPPKLRNT-------HKIS 756

Query: 320 KSFRKLLSLCLQKDPSKRPTA 340
              +  +   L +DP +R TA
Sbjct: 757 PRLQGFIDRMLVRDPHQRATA 819
>13212
          Length = 1067

 Score =  160 bits (404), Expect = 2e-39,   Method: Compositional matrix adjust.
 Identities = 85/181 (46%), Positives = 115/181 (63%), Gaps = 4/181 (2%)
 Frame = -1

Query: 176 LEEAIIATILKEVLEGLDYLHRNGQIHRDLKAGNILLGEDGSVQIADFGVSAFLATGGDV 235
           + EA I  +  E+   LD+LHR+  IHRD+KAGN+LL  DG V++ADFGVSA      + 
Sbjct: 989 MTEAQICYVCHEMCMALDFLHRHHVIHRDIKAGNVLLTIDGEVKLADFGVSA-----KNT 825

Query: 236 TRNKVRKTFVGTPCWMAPEVM--EQVRG--YDFKADMWSFGITAIELATGAAPYHKYPPM 291
              + R TF+GTP WMAPEV+  E ++   YDFKAD+WS G+T IE A    P  +  PM
Sbjct: 824 QTQQKRDTFIGTPYWMAPEVVLCETLKDTPYDFKADIWSLGVTLIEFAQIEPPNKEMHPM 645

Query: 292 KVLMLTLQNDPPTLETGVEDKEMMKKYGKSFRKLLSLCLQKDPSKRPTAAELLKCKFFQK 351
           +VL+   ++DPPTLE         KK+ K F+  ++ CL KDP+ RPTAAELL+  F ++
Sbjct: 644 RVLIKIHKSDPPTLEKP-------KKWTKLFKDFIAKCLVKDPNLRPTAAELLEHPFMKR 486

Query: 352 A 352
           A
Sbjct: 485 A 483
>18921
          Length = 697

 Score =  158 bits (399), Expect = 6e-39,   Method: Compositional matrix adjust.
 Identities = 89/212 (41%), Positives = 128/212 (60%)
 Frame = +2

Query: 73  DAYELQEVIGSGATAVVQAALCKPRQERVAIKRINLEKCQTSMDELLKEIQAMSQCSHPN 132
           D +++   +G G+   V  +L K   + +AIK++ ++   T + E++KEI  M QC    
Sbjct: 29  DVFDILGKLGEGSYGSVFKSLHKETGQVLAIKQVPVD---TDLQEIIKEISIMQQCDSKY 199

Query: 133 VVTYYTSFVVKDELWLVMKLLSGGSMLDIIKYIVNRGEHKNGVLEEAIIATILKEVLEGL 192
           +V YY S+    +LW+VM+    GS+ DI++        +N  L E  IATIL   L+GL
Sbjct: 200 IVKYYGSYFKNTDLWIVMEYCGAGSVSDIMRL-------RNKTLVEREIATILYYTLKGL 358

Query: 193 DYLHRNGQIHRDLKAGNILLGEDGSVQIADFGVSAFLATGGDVTRNKVRKTFVGTPCWMA 252
            YLH   +IHRD+KAGNILL  +G  ++ADFGV+  L      T  K R T +GTP WMA
Sbjct: 359 XYLHSRRKIHRDIKAGNILLNNEGHAKLADFGVAGQLTD----TMAK-RNTVIGTPYWMA 523

Query: 253 PEVMEQVRGYDFKADMWSFGITAIELATGAAP 284
           PEV++++ GYD  AD+WS GITA+E+A G  P
Sbjct: 524 PEVIQEI-GYDCVADIWSLGITALEMAEGKPP 616
>14420
          Length = 528

 Score =  143 bits (360), Expect = 2e-34,   Method: Compositional matrix adjust.
 Identities = 75/191 (39%), Positives = 112/191 (58%)
 Frame = +2

Query: 104 KRINLEKCQTSMDELLKEIQAMSQCSHPNVVTYYTSFVVKDELWLVMKLLSGGSMLDIIK 163
           K +NL + Q   + ++ EI  M +  +PN+V Y  S++V +ELW+VM+ L+GGS+ D++ 
Sbjct: 2   KTMNLSQ-QPKKELIINEILVMRENQNPNIVNYLDSYLVGEELWVVMEFLAGGSLTDVVT 178

Query: 164 YIVNRGEHKNGVLEEAIIATILKEVLEGLDYLHRNGQIHRDLKAGNILLGEDGSVQIADF 223
                       ++E  IA + +E L+ L++LH N  IHRD+K+ NILLG DGSV++ DF
Sbjct: 179 ---------ETCMDEGQIAAVCRECLQALEFLHENQVIHRDIKSDNILLGMDGSVKLTDF 331

Query: 224 GVSAFLATGGDVTRNKVRKTFVGTPCWMAPEVMEQVRGYDFKADMWSFGITAIELATGAA 283
           G  A L+          R T VGTP WMAPEV+ + + Y    D+WS G+  IE+  G  
Sbjct: 332 GFCAQLS-----PEQSKRSTMVGTPYWMAPEVVTR-KQYGPTVDIWSLGVMCIEMIEGEP 493

Query: 284 PYHKYPPMKVL 294
           PY    P++ L
Sbjct: 494 PYLNENPLRAL 526
>13592
          Length = 980

 Score =  113 bits (283), Expect = 2e-25,   Method: Compositional matrix adjust.
 Identities = 82/291 (28%), Positives = 146/291 (50%), Gaps = 9/291 (3%)
 Frame = +2

Query: 81  IGSGATAVVQAALCKPRQERVAIKRINLEKCQT-SMDELLKEIQAMSQCSHPNVVTYYTS 139
           IG G    V  A+     E +A+K I ++  +T ++  + +E++ +    H N+V YY  
Sbjct: 8   IGQGRFGKVYTAVNNNTGELMAMKEIAIQPGETRALKNVAEELKILEGIKHKNLVRYYGI 187

Query: 140 FVVKDELWLVMKLLSGGSMLDIIKYIVNRGEHKNGVLEEAIIATILKEVLEGLDYLHRNG 199
            V ++EL + M+L S G++  +++          G L EA+      ++L G+  LH++G
Sbjct: 188 EVHREELLIFMELCSEGTLESLVEL--------TGGLPEALSRRFTAQLLSGVAELHKHG 343

Query: 200 QIHRDLKAGNILLGE-DGSVQIADFG----VSAFLATGGDVTRNKVRKTFVGTPCWMAPE 254
            +HRD+K  NI L +   S+++ DFG    + A     G++      + +VGT  +MAPE
Sbjct: 344 IVHRDIKTANIFLVDGSNSLKLGDFGSAVKIQAHTTVPGEL------QGYVGTQAYMAPE 505

Query: 255 VMEQVR--GYDFKADMWSFGITAIELATGAAPYHKYPPMKVLMLTL-QNDPPTLETGVED 311
           V  +    G+   AD+WS G   +E+A+G  P+ ++     +M  +   + P      + 
Sbjct: 506 VFTKTNSDGHGRLADIWSVGCVVVEMASGKRPWAQFDSNFQIMFKVGMGEKP------QA 667

Query: 312 KEMMKKYGKSFRKLLSLCLQKDPSKRPTAAELLKCKFFQKAKNREYLIEKL 362
            E + + G  F   +  CLQ DP +R +A ELL+  F +  ++ E   E+L
Sbjct: 668 PESLSQEGHDF---IDHCLQHDPKQRLSAIELLEQNFCKSGRDEECNSEQL 811
>00300
          Length = 2318

 Score =  112 bits (281), Expect = 3e-25,   Method: Compositional matrix adjust.
 Identities = 83/275 (30%), Positives = 125/275 (45%), Gaps = 7/275 (2%)
 Frame = -1

Query: 81   IGSGATAVVQAALCKPRQERVAIKRINLEKCQ-TSMDELLKEIQAMSQCSHPNVVTYYTS 139
            IG G    V  A+     E +A+K +  +      + E+  EI+      H N+V YY  
Sbjct: 1634 IGEGQFGKVYTAVNMSTGELMALKEMKFQPNDLQQLREMCDEIKIFEGIQHENLVKYYGV 1455

Query: 140  FVVKDELWLVMKLLSGGSMLDIIKYIVNRGEHKNGVLEEAIIATILKEVLEGLDYLHRNG 199
             V KDE+ + M+    G++ +  K            L E +I    +E++  +++LH N 
Sbjct: 1454 EVHKDEMLMFMEYCDTGTIEEAAKM----------GLPEYLIRRYTREIVLAVNHLHENS 1305

Query: 200  QIHRDLKAGNILLGEDGSVQIADFGVSAFLATGGDVTRNKVRKTFVGTPCWMAPEVMEQV 259
             +HRD+K  NI L  +G V++ DFG S  L +    T        VGT  +MAPEV  Q 
Sbjct: 1304 IVHRDIKGANIFLTSNGHVKLGDFGCSVKLKS--HTTMPGEFHNLVGTTAYMAPEVFTQN 1131

Query: 260  R--GYDFKADMWSFGITAIELATGAAPYHKYPPMKVLMLTLQNDPPTLETGVEDK----E 313
               GY   AD+WS G   IE+ATG  P+H       +M          + G+  K    +
Sbjct: 1130 DQGGYGRAADIWSLGCVVIEMATGKRPWHDLDNNYQIM---------YKVGIGHKPAVPD 978

Query: 314  MMKKYGKSFRKLLSLCLQKDPSKRPTAAELLKCKF 348
             +   GK F   L L +  DP++R  A++LL   F
Sbjct: 977  SLSVEGKHF---LDLIMCHDPAQRALASQLLDHTF 882
>19094
          Length = 898

 Score =  109 bits (273), Expect = 3e-24,   Method: Compositional matrix adjust.
 Identities = 63/126 (50%), Positives = 82/126 (65%)
 Frame = +1

Query: 156 GSMLDIIKYIVNRGEHKNGVLEEAIIATILKEVLEGLDYLHRNGQIHRDLKAGNILLGED 215
           GS+ DI++        +N  L E  IATIL   L+GL YLH   +IHRD+KAGNILL  +
Sbjct: 10  GSVSDIMRL-------RNKTLVEREIATILYYTLKGL*YLHSRRKIHRDIKAGNILLNNE 168

Query: 216 GSVQIADFGVSAFLATGGDVTRNKVRKTFVGTPCWMAPEVMEQVRGYDFKADMWSFGITA 275
           G  ++ADFGV+  L      T  K R T +GTP WMAPEV++++ GYD  AD+WS GITA
Sbjct: 169 GHAKLADFGVAGQLTD----TMAK-RNTVIGTPYWMAPEVIQEI-GYDCVADIWSLGITA 330

Query: 276 IELATG 281
           +E+A G
Sbjct: 331 LEMAEG 348
>09606
          Length = 1300

 Score =  101 bits (251), Expect = 1e-21,   Method: Compositional matrix adjust.
 Identities = 82/297 (27%), Positives = 133/297 (44%), Gaps = 19/297 (6%)
 Frame = -3

Query: 73   DAYELQEVIGSGATAVVQAALCKPRQERVAIKRINLEKCQTSMDELLKEIQAMSQCSHPN 132
            + + L E +G G  +++     K     VAI  I  EKC+    E+   ++     SHPN
Sbjct: 1115 ENFVLYEELGKGEHSIIYKGRRKGTINFVAIHCI--EKCKRP--EVTNTVRMTHDISHPN 948

Query: 133  VVTYYTSFVVKDELWLVMKLLSGGSMLDIIKYIVNRGEHKNGVLEEAIIATILKEVLEGL 192
            VV ++  +   + LWLV++L +GGS+ DI+         ++  L E  I      ++ GL
Sbjct: 947  VVQFHEWYETSNHLWLVVELCTGGSLADILA--------QDHHLPETSIRDFGIHLVTGL 792

Query: 193  DYLHRNGQIHRDLKAGNILLGEDGSVQIADFGVSAF-----------LATGGDVTRNKVR 241
             Y+H  G +  DL+   +LL   G ++ ADFG+S              A  GD    +  
Sbjct: 791  HYIHSLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEAGDQWNIQSA 612

Query: 242  KTFV------GTPCWMAPEVMEQVRGYDFKADMWSFGITAIELATGAAPY--HKYPPMKV 293
            +  +      G+P +MAPEV +        +D+W+ G    E+ +G  P+    Y   K 
Sbjct: 611  EEMMKQVPTSGSPTYMAPEVFQGAEP-SIMSDLWALGCVFYEMFSGHPPFLGETYDITKD 435

Query: 294  LMLTLQNDPPTLETGVEDKEMMKKYGKSFRKLLSLCLQKDPSKRPTAAELLKCKFFQ 350
             +L  +   P     V+   +  K    F  LL   LQKD ++R + A L+K  F+Q
Sbjct: 434  KVLNKEFPLPK----VKGSRLSAKPSPEFLNLLESLLQKDSTRRLSWASLVKHAFWQ 276
>06405
          Length = 1965

 Score = 92.8 bits (229), Expect = 4e-19,   Method: Compositional matrix adjust.
 Identities = 78/279 (27%), Positives = 127/279 (45%), Gaps = 3/279 (1%)
 Frame = +1

Query: 68  WPICRDAYELQEVIGSGATAVVQAALCKPRQERVAIKRINLEKCQTSMDELLKEIQAMSQ 127
           W I R    ++  +G G    V  A+ K   + VA+K   L++   ++++ L+E   M +
Sbjct: 244 WEIERTEIAMKHRLGGGQYGDVYEAMWKRYNKIVAVK--TLKEDTMALNDFLEEAAIMKE 417

Query: 128 CSHPNVVTYYTSFVVKDELWLVMKLLSGGSMLDIIKYIVNRGEHKNGVLEEAIIATILKE 187
             HPN+V        +   ++V + +  G++LD   Y+ +    +NG      +AT   +
Sbjct: 418 MKHPNLVQLLGVCTREPPFYIVTEFMPHGNLLD---YLRSSTREENGPTALMYMAT---Q 579

Query: 188 VLEGLDYLHRNGQIHRDLKAGNILLGEDGSVQIADFGVSAFLATGGDVTRNKVRKTFVGT 247
           +  G+ YL     IHRDL A N L+ +   V++ADFG++  +    D     +   F   
Sbjct: 580 IASGMAYLETKNFIHRDLAARNCLVADSNMVKVADFGLARLMK--DDTYTAHIGAKFPIK 753

Query: 248 PCWMAPEVMEQVRGYDFKADMWSFGITAIELAT-GAAPYHKYPPMKVLMLTLQNDPPTLE 306
             W APE +   R +  ++D+W+FG+   ELAT G +PY      +V  L        LE
Sbjct: 754 --WTAPEGLAFNR-FSTRSDIWAFGVLLWELATYGMSPYPGVELTEVYHL--------LE 900

Query: 307 TGVEDKEMMKKYGKS--FRKLLSLCLQKDPSKRPTAAEL 343
            G     M +  G       L+  C Q DP  RPT  E+
Sbjct: 901 RGY---RMERPPGTPADVYILMLKCWQWDPKDRPTFKEI 1008
>09007
          Length = 1440

 Score = 88.2 bits (217), Expect = 8e-18,   Method: Compositional matrix adjust.
 Identities = 73/282 (25%), Positives = 128/282 (45%), Gaps = 7/282 (2%)
 Frame = -1

Query: 70  ICRDAYELQEVIGSGATAVVQAALCKPR---QERVAIKRINLEKCQTSMDELLKEIQAMS 126
           I +D   L + +G G    V+ A+       + +VA+K ++ +K      E LKE   M 
Sbjct: 888 ISKDCVALSKSLGQGHFGTVRQAIWTAESGEKVQVAVKCLSKDKIHKDGQEFLKETAIMQ 709

Query: 127 QCSHPNVVTYYTSFVVKD---ELWLVMKLLSGGSMLDIIKYIVNRGEHKNGVLEEAIIAT 183
              H N+V  Y   VV D   ++ LV +L    S+L+ +K +  R +          +  
Sbjct: 708 MLDHENIVRVYG--VVMDNGADIMLVTELAPMRSLLECVKEVSARVD-----FSVPRLCD 550

Query: 184 ILKEVLEGLDYLHRNGQIHRDLKAGNILLGEDGSVQIADFGVSAFLATGGDVTRNKVRKT 243
             ++V +G+ YL     +HRDL A NILL     V+I+D GVS  L  G +  +++    
Sbjct: 549 FSQQVCDGMSYLESKRLVHRDLAARNILLFSKSKVKISDVGVSGALGAGKEYYQSQQTIH 370

Query: 244 FVGTPCWMAPEVMEQVRGYDFKADMWSFGITAIELAT-GAAPYHKYPPMKVLMLTLQNDP 302
                 W APE    +  +   +D+W+FG+   E  T G  P+      +++      D 
Sbjct: 369 LQNAVAWCAPESFRNL-CFSSASDVWAFGVLLWEFFTHGFQPWAGLNGQQIMEAV---DA 202

Query: 303 PTLETGVEDKEMMKKYGKSFRKLLSLCLQKDPSKRPTAAELL 344
           P  +  +E  ++     K +  ++  C +++P +RPT ++L 
Sbjct: 201 PQSQR-LEQPDLCP---KEYYAVMLKCWEQEPQRRPTFSQLF 88
>30755
          Length = 1137

 Score = 87.4 bits (215), Expect = 2e-17,   Method: Compositional matrix adjust.
 Identities = 52/151 (34%), Positives = 75/151 (49%)
 Frame = +2

Query: 187 EVLEGLDYLHRNGQIHRDLKAGNILLGEDGSVQIADFGVSAFLATGGDVTRNKVRKTFVG 246
           E++  L YLH  G I+RDLK  N+LL +DG +++ADFG+        D+T  +  KTF G
Sbjct: 56  EIISALGYLHSQGIIYRDLKLENLLLDKDGHIKVADFGLCK-----EDITYGRTTKTFCG 220

Query: 247 TPCWMAPEVMEQVRGYDFKADMWSFGITAIELATGAAPYHKYPPMKVLMLTLQNDPPTLE 306
           TP ++APEV++    Y    D W  G+   E+  G  P++      +  L L        
Sbjct: 221 TPEYLAPEVLDD-NDYGRAVDWWGTGVVMYEMICGRLPFYNRDHDVLFTLIL-------- 373

Query: 307 TGVEDKEMMKKYGKSFRKLLSLCLQKDPSKR 337
             VED +  +      + LLS  L KDP  R
Sbjct: 374 --VEDVKFPRNITDEAKSLLSGLLAKDPRNR 460
>01707
          Length = 757

 Score = 85.9 bits (211), Expect = 4e-17,   Method: Compositional matrix adjust.
 Identities = 65/216 (30%), Positives = 100/216 (46%), Gaps = 5/216 (2%)
 Frame = +1

Query: 73  DAYELQEVIGSGATAVVQAALCKPRQERVAIKRINLEKCQTSMDELLK-----EIQAMSQ 127
           + YE    IG G+  VV     K   + VAIK+      ++  D L+K     EI+ + Q
Sbjct: 64  EKYEKIGKIGEGSYGVVFKCRNKETSQLVAIKKF----VESEDDPLIKKIAMREIRMLKQ 231

Query: 128 CSHPNVVTYYTSFVVKDELWLVMKLLSGGSMLDIIKYIVNRGEHKNGVLEEAIIATILKE 187
             HPN+V     F  K  L LV   +    + ++ +Y   RG      L E ++  I+ +
Sbjct: 232 LKHPNLVRLIEVFRRKKRLHLVFDYVDHTLLNELDRY--PRG------LPEPMVKRIIYQ 387

Query: 188 VLEGLDYLHRNGQIHRDLKAGNILLGEDGSVQIADFGVSAFLATGGDVTRNKVRKTFVGT 247
            L  +++ H+   IHRD+K  NIL+   G V++ DFG +  L   GD   +     +V T
Sbjct: 388 TLLAVNFCHQYNTIHRDVKPENILITRQGQVKLCDFGFARILTGPGDEYTD-----YVAT 552

Query: 248 PCWMAPEVMEQVRGYDFKADMWSFGITAIELATGAA 283
             + APE++     Y    D+W+ G    EL TG A
Sbjct: 553 RWYRAPELLVGDTQYGPPVDVWAIGCVFAELLTGQA 660
>21808
          Length = 1011

 Score = 84.7 bits (208), Expect = 8e-17,   Method: Compositional matrix adjust.
 Identities = 58/186 (31%), Positives = 89/186 (47%), Gaps = 1/186 (0%)
 Frame = +1

Query: 101 VAIKRINLEKCQTSMDELLKEIQAMSQCSHPNVVTYYTSFVVKDELWLVMKLLSGGSMLD 160
           VAIK   L+       + L E Q M +  HP ++  Y      D ++++ +L+  GS+L+
Sbjct: 28  VAIK--TLKSGTMDPKDFLAEAQIMKKLRHPKLIQLYAVCTQDDPIFIITELMKNGSLLE 201

Query: 161 IIKYIVNRGEHKNGVLEEAIIATILKEVLEGLDYLHRNGQIHRDLKAGNILLGEDGSVQI 220
            +       + K  VL+   +  I  ++  G+ YL     IHRDL A NIL+ ++ +V+I
Sbjct: 202 FL-------QGKGRVLKLPALIDIGAQIACGMAYLESQNYIHRDLAARNILVSDNNTVKI 360

Query: 221 ADFGVSAFLATGGDVTRNKVRKTFVGTPCWMAPEVMEQVRGYDFKADMWSFGITAIELAT 280
           ADFG++  +       R   R        W APE     R +  K+D+WSFGI   E  T
Sbjct: 361 ADFGLARVIKEDEYEARVGARFPIK----WTAPEAANYNR-FTIKSDVWSFGILLTETVT 525

Query: 281 -GAAPY 285
            G  PY
Sbjct: 526 YGRVPY 543
>37602
          Length = 804

 Score = 84.0 bits (206), Expect = 2e-16,   Method: Compositional matrix adjust.
 Identities = 41/91 (45%), Positives = 58/91 (63%)
 Frame = -1

Query: 133 VVTYYTSFVVKDELWLVMKLLSGGSMLDIIKYIVNRGEHKNGVLEEAIIATILKEVLEGL 192
            V Y+ S++ +++LW+ M+   GGSM DI         H  G L E  IA + +E L+GL
Sbjct: 333 FVGYFDSYLRREKLWIAMEYCGGGSMQDIY--------HVTGPLTEPQIAFVCRETLKGL 178

Query: 193 DYLHRNGQIHRDLKAGNILLGEDGSVQIADF 223
            YLHR G++HRD+K  NILL E+G V++ADF
Sbjct: 177 HYLHRRGKMHRDIKGANILLTEEGDVKLADF 85

 Score = 30.8 bits (68), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 17/33 (51%), Positives = 20/33 (60%), Gaps = 1/33 (3%)
 Frame = -1

Query: 221 ADFGVSAFLATGGDVTRNKV-RKTFVGTPCWMA 252
           ADFGVSA       +T     RK+F+GTP WMA
Sbjct: 747 ADFGVSA------QITATMCKRKSFIGTPYWMA 667
>03240
          Length = 1683

 Score = 82.0 bits (201), Expect = 5e-16,   Method: Compositional matrix adjust.
 Identities = 61/259 (23%), Positives = 111/259 (42%), Gaps = 43/259 (16%)
 Frame = -3

Query: 75   YELQEVIGSGATAVVQAALCKPRQERVAIKRINLEKCQTSMDELLKEIQA----MSQCSH 130
            +E  + +G GA   V  +LC+     +      L K        +  ++A    +++  +
Sbjct: 1285 FEKIKTLGVGAFGEV--SLCRKNDTGMLYAMKTLRKSDVLKRNQVAHVKAERDILAEADN 1112

Query: 131  PNVVTYYTSFVVKDELWLVMKLLSGGSMLDIIKYIVNRGEHKNGVLEEAIIATILKEVLE 190
              VV  Y SF   + L+ VM  + GG ++ ++  +         +L+E +    + E+++
Sbjct: 1111 EWVVKLYYSFQDHNYLYFVMDYVPGGDLMGLLIRM--------EILDEPLARFYVAELVQ 956

Query: 191  GLDYLHRNGQIHRDLKAGNILLGEDGSVQIADFGV---------SAFLATGGDVTRN--- 238
             ++ +HR G IHRD+K  NIL+  +G +++ DFG+         S +    G   R    
Sbjct: 955  AIESVHRMGFIHRDIKPDNILIDRNGHIKLTDFGLCTGFRWTHNSKYYQRDGTHARQDSM 776

Query: 239  -------------------KVRK--------TFVGTPCWMAPEVMEQVRGYDFKADMWSF 271
                               + RK        + VGTP ++APEV+ ++ GY    D WS 
Sbjct: 775  EVKCQLDEQCQCEILKPLERRRKREQRCLAHSLVGTPNYIAPEVLSRLGGYTSVCDWWSV 596

Query: 272  GITAIELATGAAPYHKYPP 290
            G+   E+  G  P++   P
Sbjct: 595  GVILFEMLVGHPPFYANTP 539
>18484
          Length = 635

 Score = 81.6 bits (200), Expect = 7e-16,   Method: Compositional matrix adjust.
 Identities = 55/171 (32%), Positives = 85/171 (49%), Gaps = 4/171 (2%)
 Frame = +1

Query: 171 HKNGVLEEAIIATILKEVLEGLDYLHRNGQIHRDLKAGNILLGEDGSVQIADFGVSAFLA 230
            + G  +E + A    E+  GL +LH  G I+RDLK  N++L  +G ++IADFG+     
Sbjct: 19  QQEGKFKEPVAAFYAAEIAVGLFFLHDQGIIYRDLKLDNVMLDSEGHIKIADFGMCKEGM 198

Query: 231 TGGDVTRNKVRKTFVGTPCWMAPEVMEQVRGYDFKADMWSFGITAIELATGAAPYHKYPP 290
           TG   TR     TF GTP ++APE++   + Y    D W++G+   E+  G  P+     
Sbjct: 199 TGDATTR-----TFCGTPDYIAPEIV-LYQPYSKSVDWWAYGVLLFEMLAGQPPFDG--- 351

Query: 291 MKVLMLTLQNDPPTLETGVEDKEMMKKYGKSF-RKLLSLC---LQKDPSKR 337
                     D   L + + D  +   Y K+  R+ +SLC   L K+P+KR
Sbjct: 352 ---------EDEDELFSSITDHNV--SYPKAMSREAVSLCKGLLMKNPTKR 471
>14126
          Length = 1265

 Score = 80.9 bits (198), Expect = 1e-15,   Method: Compositional matrix adjust.
 Identities = 69/221 (31%), Positives = 110/221 (49%), Gaps = 10/221 (4%)
 Frame = +3

Query: 75  YELQEVIGSGATAVVQAAL-CKPRQERVAIKRINLEKCQTSMDEL-LKEI---QAMSQCS 129
           YE   VIG+GA   V  A   + + E VA+KRI L   +  M  + ++EI   + + Q  
Sbjct: 195 YEEVAVIGNGAYGTVYKARDLRNQGEFVAMKRIRLNNTEEGMPMMAIREISMLKQLEQYE 374

Query: 130 HPNVV-----TYYTSFVVKDELWLVMKLLSGGSMLDIIKYIVNRGEHKNGVLEEAIIATI 184
           HPNVV     ++ T    +  L LV + +      D+  Y+    +  +  L    I  +
Sbjct: 375 HPNVVRLLDVSHNTITDREIRLNLVFEYIEH----DLATYL---AKCPSPGLGPDRIKDL 533

Query: 185 LKEVLEGLDYLHRNGQIHRDLKAGNILLGEDGSVQIADFGVSAFLATGGDVTRNKVRKTF 244
           + ++L G+D+LH N  +HRDLK  N+L+ +DG +++ADFG++   +    +T      T 
Sbjct: 534 MLQLLNGVDFLHSNRIVHRDLKPQNLLISKDGRLKLADFGLARIYSFHMALT------TV 695

Query: 245 VGTPCWMAPEVMEQVRGYDFKADMWSFGITAIELATGAAPY 285
           V T  + +PEV+ Q   Y    D+WS G    EL T  A +
Sbjct: 696 VVTLWYRSPEVLMQAE-YGTSVDIWSCGCIFAELFTRRALF 815
>01718
          Length = 959

 Score = 80.9 bits (198), Expect = 1e-15,   Method: Compositional matrix adjust.
 Identities = 77/285 (27%), Positives = 131/285 (45%), Gaps = 9/285 (3%)
 Frame = +3

Query: 79  EVIGSGATAVVQAALCKPRQERVAIKRINLEKCQTSMDELLKEIQAMSQCSHPNVVTYYT 138
           E IG+G  + V     +   + +A+K   +    ++   +L+E+Q +++  H N++ +  
Sbjct: 165 EKIGAGFFSEVFKVTHRITGQVMALK---MNTMTSNRHNMLREVQLLNRLQHANILRFMG 335

Query: 139 SFVVKDELWLVMKLLSGGSMLDIIKYIVNRGEHKNGVLEEAIIATILKEVLEGLDYLHRN 198
             V + +L  + + +  G++  ++       E K+  L       +   +  GLDYLH  
Sbjct: 336 VCVHEGQLHALTEYIPSGNLEQLL-------EKKDEELPWTQRIQLTLGLARGLDYLHST 494

Query: 199 GQIHRDLKAGNILLGEDGS----VQIADFGVSAFLATGGDVTRNKVRKTFVGTPCWMAPE 254
             IHRDL + NIL+  + +      IADFG    LAT      +K +   VG+P WMAPE
Sbjct: 495 RFIHRDLTSKNILIRREDNHGYHAVIADFG----LATKIPDPLDKEKLPTVGSPYWMAPE 662

Query: 255 VMEQVRGYDFKADMWSFGITAIELATGAAPYHKYPPMKVLMLTLQNDPPTLETGVED--- 311
           V+     Y+ +AD++S GI   E+        + P    +M  + N       GV+    
Sbjct: 663 VLNG-HFYNERADLFSVGIIMCEITA------RIPADPDIMPRMNN------FGVDYVAL 803

Query: 312 KEMMKKYGKSFRKLLSLCLQKDPSKRPTAAELLKC--KFFQKAKN 354
            EM+      + +L   C Q DP KRP   E+++   K F+  KN
Sbjct: 804 SEMISYCPLDYLQLAFKCCQVDPQKRPRGVEIIEWLEKIFKNLKN 938
>00392
          Length = 668

 Score = 80.1 bits (196), Expect = 2e-15,   Method: Compositional matrix adjust.
 Identities = 59/177 (33%), Positives = 94/177 (53%), Gaps = 8/177 (4%)
 Frame = +3

Query: 117 ELLKEIQAMSQCSHPNVVTYYTSFVVKDE-----LWLVMKLLSGGSMLDIIKYIVNRGEH 171
           E+LKE+Q      HPN+V ++  +   +      + LV +L++ G++    K  + R + 
Sbjct: 87  EMLKELQ------HPNIVRFFDYWEEHNHRNRKVIILVTELMTSGTL----KTYLKRFKK 236

Query: 172 KNGVLEEAIIATILKEVLEGLDYLHRNGQ--IHRDLKAGNILL-GEDGSVQIADFGVSAF 228
            N      I+    ++VL+GL +LH      IHRDLK  NI + G  GSV+I D G    
Sbjct: 237 PNV----KILKNWCRQVLKGLYFLHTRTPPVIHRDLKCDNIFITGPTGSVKIGDLG---- 392

Query: 229 LATGGDVTRNKVRKTFVGTPCWMAPEVMEQVRGYDFKADMWSFGITAIELATGAAPY 285
           LAT   +      K+ +GTP +MAPE+ E+   YD   D+++FG+  +E+A+   PY
Sbjct: 393 LAT---LKNQSFAKSVIGTPEFMAPEMYEE--HYDEAVDVYAFGMCMLEMASSEYPY 548
>15910
          Length = 1361

 Score = 79.7 bits (195), Expect = 3e-15,   Method: Compositional matrix adjust.
 Identities = 60/214 (28%), Positives = 102/214 (47%), Gaps = 7/214 (3%)
 Frame = +2

Query: 156 GSMLDIIKYIVNRGEHKNGVLEEAIIATILKEVLEGLDYLHRNGQIHRDLKAGNIL---L 212
           G   ++   IV RG++      E   A  + ++L G+ Y+H NG +HRDLK  N+L   +
Sbjct: 410 GEWWELFDRIVTRGQYT-----EKDAARAISDILHGVQYIHANGVVHRDLKPENLLYECM 574

Query: 213 GEDGSVQIADFGVSAFLATGGDVTRNKVRKTFVGTPCWMAPEVMEQVRGYDFKADMWSFG 272
            +D  +++ADFG+S  +     ++      T  GTP + APEV++  + Y    DMWS G
Sbjct: 575 TDDSKLKLADFGLSRIIEPEVQMS------TVCGTPGYCAPEVLKGDK-YTPSVDMWSVG 733

Query: 273 ITAIELATGAAPYHKYPPMKVLMLTLQNDPPTLETGVEDKEMMKKYGKSFRKLLSLCLQK 332
           + A  L  G  P+      ++    ++ +         D+E   +  ++ + ++   L  
Sbjct: 734 VIAYILLCGYEPFFAENEFEMYRKIIKGEYKF------DEEYWSEISENAKDVVRKLLVI 895

Query: 333 DPSKRPTAAELLKCKFFQ----KAKNREYLIEKL 362
           DP KR TA E L+  + +    K  N E  + KL
Sbjct: 896 DPKKRLTATEALRLPWVKGVATKTTNMEITMNKL 997
>17975
          Length = 449

 Score = 77.8 bits (190), Expect = 1e-14,   Method: Composition-based stats.
 Identities = 50/145 (34%), Positives = 76/145 (52%), Gaps = 2/145 (1%)
 Frame = +3

Query: 87  AVVQAALCKPRQERVAIKRINLEKC-QTSMDELLKEIQAMSQCSHPNVVTYYTSFVVKDE 145
           AVV+ A      E+VA+K I+  K  + S   L +E++ M    HPNVV  Y     + +
Sbjct: 9   AVVKLARHVFTGEKVAVKVIDKTKLDEVSRSHLFQEVRCMKLVQHPNVVRLYEVIDTQTK 188

Query: 146 LWLVMKLLSGGSMLDIIKYIVNRGEHKNGVLEEAIIATILKEVLEGLDYLHRNGQIHRDL 205
           L+L+++L  GG M D I        H  G LEE +     ++++E + Y H+   +HRDL
Sbjct: 189 LYLILELGDGGDMYDYIM------RHSGG-LEEKLAKRYFRQIVEAISYCHKLHVVHRDL 347

Query: 206 KAGNILLGED-GSVQIADFGVSAFL 229
           K  N++  E  G V++ DFG S  L
Sbjct: 348 KPENVVFFEKPGLVKLTDFGFSTCL 422
>01756
          Length = 1858

 Score = 77.4 bits (189), Expect = 1e-14,   Method: Compositional matrix adjust.
 Identities = 68/229 (29%), Positives = 106/229 (46%), Gaps = 14/229 (6%)
 Frame = -3

Query: 66   VGWPIC-RDA-YELQEVIGSGATAVVQAALCKPRQERVAIKRINLEKCQTSMD-ELLKEI 122
            + +P C  DA YE    IG G    V  A CK  ++ VA+K++ ++  +       L+EI
Sbjct: 1769 LKFPFCDEDAKYEKLAKIGQGTFGEVFKARCKKTKQVVAMKKVLMDNEKEGFPITALREI 1590

Query: 123  QAMSQCSHPNVV-------TYYTSF-VVKDELWLVMKLLSG--GSMLDIIKYIVNRGEHK 172
            + +   +H NVV       T  TS    K   +LV +        +L  +  + N  E  
Sbjct: 1589 KILQLLNHENVVDLIEICSTKATSANRYKSMFYLVFEFCEHDLAGLLSNMSVVFNLPE-- 1416

Query: 173  NGVLEEAIIATILKEVLEGLDYLHRNGQIHRDLKAGNILLGEDGSVQIADFGVS-AFLAT 231
                    I  ++K+++ GL Y+HRN  +HRD+KA NIL+ + G +++ADFG++ AF   
Sbjct: 1415 --------IKEVMKQLMNGLYYIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVN 1260

Query: 232  GGDVTRNKVRKTFVGTPCWMAPEVMEQVRGYDFKADMWSFGITAIELAT 280
                 R   R   V T  +  PE++   R Y    D W  G    E+ T
Sbjct: 1259 LRQPNRYTNR---VVTLWYRPPELLLGDRNYSTAIDQWGAGCIMAEMWT 1122
>26560
          Length = 398

 Score = 76.6 bits (187), Expect = 2e-14,   Method: Composition-based stats.
 Identities = 41/117 (35%), Positives = 69/117 (58%)
 Frame = -1

Query: 172 KNGVLEEAIIATILKEVLEGLDYLHRNGQIHRDLKAGNILLGEDGSVQIADFGVSAFLAT 231
           ++GV  E  +     EV+ GL+++H    ++RDLK  NILL E+G V+I+D G++     
Sbjct: 377 QHGVFTEKEVRFYAAEVMLGLEHMHSRFVVYRDLKPANILLDENGHVRISDLGLAC---- 210

Query: 232 GGDVTRNKVRKTFVGTPCWMAPEVMEQVRGYDFKADMWSFGITAIELATGAAPYHKY 288
             D ++ +   + VGT  +MAPEV+ + + YD  AD +SFG    +L  G +P+ ++
Sbjct: 209 --DFSKKRPHAS-VGTHGYMAPEVLMKGQSYDSSADWFSFGCMLYKLLKGHSPFRQH 48
>04852
          Length = 1462

 Score = 76.3 bits (186), Expect = 3e-14,   Method: Compositional matrix adjust.
 Identities = 68/279 (24%), Positives = 119/279 (42%), Gaps = 30/279 (10%)
 Frame = +1

Query: 96  PRQERVAIKRINLEKCQTSMDELLKEIQAMSQC----SHPNVVTYYTSFVVKDELWLVMK 151
           P+   VA+K +          + ++E+Q M       SH N+V +         LW++++
Sbjct: 13  PKASTVAVKMLRDIVTAVEEQDFVQELQVMKAVKKMGSHINIVNFLGCCTQGGPLWVIVE 192

Query: 152 LLSGGSMLDIIK--------------------YIVNRGEHKNGVLEEAIIATILKEVLEG 191
               G++ D ++                    Y    G H   V+    + +   ++  G
Sbjct: 193 FAKNGNLRDFLESCRDGINGYGKFVSPQDPGWYTKTPGGH---VIRRKNLLSYAFQIARG 363

Query: 192 LDYLHRNGQIHRDLKAGNILLGEDGSVQIADFGVSAFLATGGDVTRNKVRKTFVGTPC-W 250
           +++L     IHRDL A N+L+ E+  ++IADFG    L+  GD  +   +++    P  W
Sbjct: 364 MEFLASRKCIHRDLAARNVLVTEEHVLKIADFG----LSRTGDYYK---KRSGGRLPVKW 522

Query: 251 MAPEVMEQVRGYDFKADMWSFGITAIEL-ATGAAPYHKYPP----MKVLMLTLQNDPPTL 305
           MAPE +  +R Y  K+D+WSFG+   E+ + G  PY   P      K+L    +   P L
Sbjct: 523 MAPEALFDMR-YTTKSDVWSFGVVLWEIFSLGGMPYASIPNEELYSKLLDDAYRMPRPEL 699

Query: 306 ETGVEDKEMMKKYGKSFRKLLSLCLQKDPSKRPTAAELL 344
            +G            +   ++  C    PS RP  ++L+
Sbjct: 700 ASG------------NLYAIMERCWLNRPSDRPEFSQLV 780
>01060
          Length = 1800

 Score = 75.5 bits (184), Expect = 5e-14,   Method: Compositional matrix adjust.
 Identities = 51/193 (26%), Positives = 94/193 (48%), Gaps = 1/193 (0%)
 Frame = +1

Query: 81  IGSGATAVVQAALCKPRQERVAIKRINLEKCQTSM-DELLKEIQAMSQCSHPNVVTYYTS 139
           IG G   VV     +    ++A+K+I L   +  +    ++EI  + +  H N+V     
Sbjct: 97  IGEGTYGVVYKCRHRATGRKLAMKKIRLRGSEDGVPSSAIREIAMLRELRHTNIVCLEDV 276

Query: 140 FVVKDELWLVMKLLSGGSMLDIIKYIVNRGEHKNGVLEEAIIATILKEVLEGLDYLHRNG 199
            +  + L+LV + LS    +D+  YI    E    VL+  ++ + + +++ G+ + H+  
Sbjct: 277 IMEDERLFLVFEFLS----MDLKMYIDKFPE--GVVLDRRLVKSYVFQIVTGIXFCHQRR 438

Query: 200 QIHRDLKAGNILLGEDGSVQIADFGVSAFLATGGDVTRNKVRKTFVGTPCWMAPEVMEQV 259
            +HRDLK  N+L+   G+++IADFG++   A       ++     V T  + APE++   
Sbjct: 439 IVHRDLKPQNLLINHTGAIKIADFGMARTFALPVRAYTHE-----VVTLWYRAPEILMGA 603

Query: 260 RGYDFKADMWSFG 272
             Y    D+WS G
Sbjct: 604 SKYSTPVDVWSIG 642
>31885
          Length = 529

 Score = 74.3 bits (181), Expect = 1e-13,   Method: Compositional matrix adjust.
 Identities = 47/168 (27%), Positives = 82/168 (48%), Gaps = 4/168 (2%)
 Frame = -2

Query: 122 IQAMSQCSHPNVVTYYTSFVVKDELWLVMKLLSGGSMLDIIKYIVNRGEHKNGVLEEAII 181
           +  +++  HP +V  + +F  +++L++V+ L  GG +   ++  V+          E  +
Sbjct: 519 VDMLTRLDHPFLVNLWYAFQDEEDLFMVVDLFLGGDLRYHMQQEVS--------FREDCV 364

Query: 182 ATILKEVLEGLDYLHRNGQIHRDLKAGNILLGEDGSVQIADFGVSAFLATGGDVTRNKVR 241
              L ++   LDYL     +HRD+K  NILL E G   + DF ++  L        +++ 
Sbjct: 363 KFYLCQLALVLDYLRSQKIVHRDIKPDNILLDEQGHCHVTDFNIATQLED------DELA 202

Query: 242 KTFVGTPCWMAPEV----MEQVRGYDFKADMWSFGITAIELATGAAPY 285
            +  GT  +MAPEV    + + RGY F  D WS G++  EL     P+
Sbjct: 201 TSTSGTRPYMAPEVYGVAINERRGYGFPVDWWSLGVSLFELLKKRRPF 58
>21079
          Length = 878

 Score = 72.8 bits (177), Expect = 4e-13,   Method: Compositional matrix adjust.
 Identities = 51/184 (27%), Positives = 84/184 (45%), Gaps = 11/184 (5%)
 Frame = +1

Query: 130 HPNVVTYYTSFVVKDELWLVMKLLSGGSMLDIIKYIVNRGEHKNGVLEEAIIATILKEVL 189
           HP ++  + +F     + LVM+ +  G + +       R    + VL E      ++++ 
Sbjct: 1   HPKLLMLWDAFEAPRTMVLVMEFVGAGELFE-------RVIRDDFVLTERDCVHFVRQIC 159

Query: 190 EGLDYLHRNGQIHRDLKAGNILLGEDGS--VQIADFGVSAFLATGGDVTRNKVRKTFVGT 247
            G+ Y+H    +H DLK  N+L   D S  ++I DFG++ F   G  +      +   GT
Sbjct: 160 SGVGYMHTQSILHLDLKPENVLCVSDNSNQIKIIDFGLARFYKPGDSL------QVLFGT 321

Query: 248 PCWMAPEVMEQVRGYD---FKADMWSFGITAIELATGAAP------YHKYPPMKVLMLTL 298
           P ++APEV+     YD   F  DMWS G+    L +G +P         +P  +V+  TL
Sbjct: 322 PEFIAPEVV----NYDEINFTTDMWSIGVICYILLSGLSPSRVTTMLRPWPTSQVVTTTL 489

Query: 299 QNDP 302
              P
Sbjct: 490 TMIP 501
>27405
          Length = 532

 Score = 71.2 bits (173), Expect = 9e-13,   Method: Compositional matrix adjust.
 Identities = 44/139 (31%), Positives = 77/139 (55%)
 Frame = -3

Query: 131 PNVVTYYTSFVVKDELWLVMKLLSGGSMLDIIKYIVNRGEHKNGVLEEAIIATILKEVLE 190
           P +V    +F   ++L  ++ L++GG     + Y ++    ++GV  E  +     EV+ 
Sbjct: 374 PFIVCMTYAFQTPEKLCFILDLMNGGD----LHYHLS----QHGVFTEKEVRFYAAEVML 219

Query: 191 GLDYLHRNGQIHRDLKAGNILLGEDGSVQIADFGVSAFLATGGDVTRNKVRKTFVGTPCW 250
           GL+++H    ++RDLK  NILL E+G V+I+D G++       D ++ K   + VGT  +
Sbjct: 218 GLEHMHSRFVVYRDLKPANILLDENGHVRISDLGLAC------DFSKKKPHAS-VGTHGY 60

Query: 251 MAPEVMEQVRGYDFKADMW 269
           MAPEV+ + + YD  AD +
Sbjct: 59  MAPEVLMKGQAYDSSADWF 3
>01392
          Length = 1806

 Score = 70.9 bits (172), Expect = 1e-12,   Method: Compositional matrix adjust.
 Identities = 54/193 (27%), Positives = 91/193 (47%), Gaps = 21/193 (10%)
 Frame = -1

Query: 174  GVLEEAIIATILKEVLEGLDYLHRNGQIHRDLKAGNIL---LGEDGSVQIADFGVSAFLA 230
            G L E   + +++ +   LD+LH  G  HRDLK  NIL   L +   V+I DF +++ ++
Sbjct: 1806 GHLCEREASLVVRHIARALDFLHSKGIAHRDLKPENILCEHLDDVVPVKICDFDLASGIS 1627

Query: 231  TGGDVTRNKVRKTFVGTPCWMAPEVMEQVRG----YDFKADMWSFGITAIELATGAAPYH 286
              GD T+     T VG+  +MAPEV++   G    YD + D+WS GI    +  G  P++
Sbjct: 1626 CDGDGTKTPELLTPVGSAEYMAPEVVDAWVGDSFSYDKRCDLWSLGIILYIMLCGYPPFY 1447

Query: 287  K--------------YPPMKVLMLTLQNDPPTLETGVEDKEMMKKYGKSFRKLLSLCLQK 332
                           +    +L  ++Q+      +     +       S + L+   L +
Sbjct: 1446 GQCGEDCGWNRGEACHDCQDMLFNSIQDGHYKFPS-----QEWTSISSSAKDLIRHLLVR 1282

Query: 333  DPSKRPTAAELLK 345
            +P KR +AA++LK
Sbjct: 1281 EPRKRYSAADVLK 1243
>07291
          Length = 833

 Score = 70.1 bits (170), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 55/201 (27%), Positives = 94/201 (46%), Gaps = 7/201 (3%)
 Frame = +1

Query: 186 KEVLEGLDYLHRNGQIHRDLKAGNILLGEDGSVQIADFGVSAFL-----ATGGDVTRNKV 240
           +++ +G+ YL     +HR+L A N ++ EDG +Q++D+GV+  L      T  D     +
Sbjct: 70  RQIADGMAYLQEVKVVHRNLAARNCIVTEDGRLQLSDYGVTGSLFPQSYYTADDSPARDL 249

Query: 241 RKTFVGTPCWMAPEVMEQVRGYDFKADMWSFGITAIELAT-GAAPYHKYPPMKVLMLTLQ 299
            K       WMAPE ++    +  K+D+W+FG+   EL T G  PY       +L     
Sbjct: 250 VK-------WMAPETIDNFH-FSSKSDVWAFGVVLWELLTRGITPYPDVENSSLL----- 390

Query: 300 NDPPTLETGVEDKEMMKKYGKSFRKLLSLCLQKDPSKRPTAAELL-KCKFFQKAKNREYL 358
              P L+ G   K+  K+  +   ++++ C  + P +RP  AEL  + K F    N    
Sbjct: 391 ---PYLKEGHRMKK-PKQSPEPVYEMMTACWNESPEQRPDFAELNDQLKTFTNTDNTTSD 558

Query: 359 IEKLLTRTPDIAQRAKKVRRV 379
              LL  + D+    + V+ +
Sbjct: 559 TTALLNNSVDVGGSTEYVQVI 621
>14116
          Length = 1017

 Score = 70.1 bits (170), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 67/218 (30%), Positives = 106/218 (48%), Gaps = 7/218 (3%)
 Frame = -1

Query: 70  ICRDAYELQEVIGSGATAVVQ-AALCKPRQE---RVAIKRI-NLEKCQTSMDELLKEIQA 124
           I R+   + E IG G    V+   L  P Q+    VA+K + N    +  +   L+E   
Sbjct: 645 IDREFLTMGEEIGKGNFGCVKRGFLTLPEQKGDILVAVKTLHNNNPREIELQSFLQEALI 466

Query: 125 MSQCSHPNVVTYYTSFVVKDELWLV-MKLLSGGSMLDIIKYIVNRGEHKNGVLEEAIIAT 183
           M    H NV+T     +  D++ LV +  +  G   D++ YI  R +     +++ I+  
Sbjct: 465 MKDFHHSNVLTLIGICLNLDDMPLVVLPFMKHG---DLLTYI--RDDQHQPTIKDLIMYG 301

Query: 184 ILKEVLEGLDYLHRNGQIHRDLKAGNILLGEDGSVQIADFGVSAFLATGGDV-TRNKVRK 242
           +  ++  G+DYL     +HRDL A N +L ED  V++ADFG++  +       + NK  K
Sbjct: 300 V--DIARGMDYLAGLKFVHRDLAARNCMLDEDFHVKVADFGLARDIYEKEYYSSENKKAK 127

Query: 243 TFVGTPCWMAPEVMEQVRGYDFKADMWSFGITAIELAT 280
             V    WMA E +E+   YD K D+WS+G+   EL T
Sbjct: 126 LPVK---WMALESLEK-GNYDSKTDVWSYGVVLWELLT 25
>11780
          Length = 1713

 Score = 68.6 bits (166), Expect = 7e-12,   Method: Compositional matrix adjust.
 Identities = 59/225 (26%), Positives = 102/225 (45%), Gaps = 7/225 (3%)
 Frame = +3

Query: 67  GWPICRDAYELQEVIGSGATAVVQAALCKPRQERVAIKRINLEKCQTSMDELLKEIQAMS 126
           GW I     E+ E IG G    V   +   R + VAIK+  L+         L+E   M+
Sbjct: 579 GWVIAXQDLEIGEAIGKGDFGDVYKGMY--RGQPVAIKQ--LKDKDRGEQSFLQEASVMT 746

Query: 127 QCSHPNVVTYYTSFVVKDELWLVMKLLSGGSMLDIIKYIVNRGEHKNGVLEEAIIATILK 186
              H N+V      V+ + ++LV + +  G   ++++Y+ +RG     V+ +        
Sbjct: 747 SLRHDNLVRL-IGVVLGETIFLVTEFMGKG---NLVEYLRSRGR---SVITKKDQINFAT 905

Query: 187 EVLEGLDYLHRNGQIHRDLKAGNILLGEDGSVQIADFGVSAFLATGGDVTRNKVRKTFVG 246
           +    ++YL     +HRDL A N+L+ +DG  +++DFG++ F    GD ++  V+     
Sbjct: 906 DTCAAMEYLESKRLVHRDLAARNVLVHDDGKAKVSDFGLAKF----GDFSQTSVK----- 1058

Query: 247 TPC-WMAPEVME------QVRGYDFKADMWSFGITAIELATGAAP 284
            P  W APE +       QVR      ++W   +  + L + A P
Sbjct: 1059FPIKWTAPEALRENKIH*QVR----HVELWHIVMGNLLLWSSALP 1181

 Score = 32.7 bits (73), Expect = 0.38,   Method: Compositional matrix adjust.
 Identities = 24/81 (29%), Positives = 37/81 (45%), Gaps = 1/81 (1%)
 Frame = +1

Query: 265  KADMWSFGITAIELAT-GAAPYHKYPPMKVLMLTLQNDPPTLETGVEDKEMMKKYGKSFR 323
            K+DMWSFGI   E+ + G  PY + P   V+M         +E G    E  +       
Sbjct: 1114 KSDMWSFGILLWEIYSFGRVPYPRIPLTDVVM--------HVERGYR-MEAPEGCPPEIY 1266

Query: 324  KLLSLCLQKDPSKRPTAAELL 344
             ++    + DP++RPT   +L
Sbjct: 1267 SIMKQAWELDPNERPTFKSVL 1329
>00715
          Length = 1788

 Score = 66.6 bits (161), Expect = 3e-11,   Method: Compositional matrix adjust.
 Identities = 62/240 (25%), Positives = 110/240 (45%), Gaps = 25/240 (10%)
 Frame = +1

Query: 130 HPNVVTYYTSFVV---KDELWLVMKLLSGGSMLDIIKYIVNRGEHKNGVLEEAIIATILK 186
           H NVV+   +  +   +D  WL M+ +   ++  I+       +H+  + + ++  ++  
Sbjct: 103 HVNVVSILGATSLHRFEDGAWLAMEYVGPLNLQTILN------DHQQDI-DSSMRLSLAL 261

Query: 187 EVLEGLDYLHRNGQIHRDLKAGNILLGEDGSVQIADFGVSAFLA-TG-------GDVTRN 238
           ++  GL YLH    +H DLK  N LL  D  ++IADFG    L  TG       G +  N
Sbjct: 262 QMARGLHYLHSINIVHLDLKPANCLLTRDLKLRIADFGCCHQLTPTGLDMGEREGGMAGN 441

Query: 239 KVRKT---------FVGTPCWMAPEVMEQVRGYDFKADMWSFGITAIELATGAAPYHKYP 289
           ++  T           GT  + APE+++ ++    ++D++S GIT  ++ T   PY   P
Sbjct: 442 ELELTPVQGAWKNELAGTLAYRAPELLKGLQP-SVRSDVYSLGITLWQMCTRQGPYEGVP 618

Query: 290 PMKVLMLTLQND-----PPTLETGVEDKEMMKKYGKSFRKLLSLCLQKDPSKRPTAAELL 344
              V+   +  D     PP+ E   +  E+M      FR L + C  +    RPT+ +++
Sbjct: 619 AHAVVYQVVSKDLRPCPPPSTED--DPFEVM------FRDLYTQCWARRVEDRPTSLDVV 774
>28638
          Length = 1458

 Score = 48.9 bits (115), Expect(2) = 6e-11,   Method: Compositional matrix adjust.
 Identities = 32/86 (37%), Positives = 43/86 (50%), Gaps = 2/86 (2%)
 Frame = -1

Query: 201 IHRDLKAGNILLG--EDGSVQIADFGVSAFLATGGDVTRNKVRKTFVGTPCWMAPEVMEQ 258
           IH DLK  NILL   +  +++I DFG S  L   G      ++  F     + +PEV+  
Sbjct: 765 IHCDLKPENILLCNPKRSAIKIVDFGSSCQL---GQRIYQYIQSRF-----YRSPEVLLG 610

Query: 259 VRGYDFKADMWSFGITAIELATGAAP 284
           V  YD   DMWS G   +E+ TG  P
Sbjct: 609 V-PYDLAIDMWSLGCILVEMHTGEPP 535

 Score = 36.6 bits (83), Expect(2) = 6e-11,   Method: Compositional matrix adjust.
 Identities = 30/101 (29%), Positives = 53/101 (52%), Gaps = 4/101 (3%)
 Frame = -3

Query: 73   DAYELQEVIGSGATAVVQAALCKPRQERVAIKRINLEKCQTSMDEL-LKEIQAMSQCSHP 131
            D YE+  +IG G+   V  A     QE+VAIK I  +K   +  ++ +K ++ M++    
Sbjct: 1147 DRYEIDSLIGKGSFGQVVKAYDHGDQEQVAIKIIKNKKPFLNQAQIEVKLLELMNRHDAD 968

Query: 132  N---VVTYYTSFVVKDELWLVMKLLSGGSMLDIIKYIVNRG 169
            N   +V     F+ ++ L LV +LLS  ++ D+++    RG
Sbjct: 967  NXYYIVRLKRHFMFRNHLCLVFELLS-YNLYDLLRNTNFRG 848
>07940
          Length = 1336

 Score = 64.7 bits (156), Expect = 8e-11,   Method: Compositional matrix adjust.
 Identities = 45/127 (35%), Positives = 67/127 (52%), Gaps = 6/127 (4%)
 Frame = -3

Query: 169 GEHKNGVLEEAI---IATILKEVLEGLDYLHRNGQIHRDLKAGNILLGEDGSVQIADFGV 225
           G H+  +L+      + +   +V  G++YL     IHRDL A N+L+ E+  ++IADFG+
Sbjct: 386 GSHRQDMLKMLTPKDLISYAYQVARGMEYLASKQCIHRDLAARNVLVAEEYVLKIADFGL 207

Query: 226 SAFLATGGDVTRNKVRKTFVG-TPC-WMAPEVMEQVRGYDFKADMWSFGITAIELAT-GA 282
           +  L        +  RKT  G  P  WMAPE +   R Y  K+D+WS+G+   E+ T G 
Sbjct: 206 TRNLQ-----QFDYYRKTTDGRLPVKWMAPEALFD-RKYTSKSDVWSYGVLLWEIFTLGG 45

Query: 283 APYHKYP 289
            PY   P
Sbjct: 44  NPYPSVP 24
>13066
          Length = 551

 Score = 64.7 bits (156), Expect = 9e-11,   Method: Compositional matrix adjust.
 Identities = 45/178 (25%), Positives = 81/178 (45%), Gaps = 2/178 (1%)
 Frame = +3

Query: 97  RQERVAIKRINLEKCQTSMDELL--KEIQAMSQCSHPNVVTYYTSFVVKDELWLVMKLLS 154
           R  ++A K I+ EK      E    +E+  +++  HP ++  ++      + ++ M+   
Sbjct: 48  RNIKLACKIIDKEKAPVDFVEKFFPRELDLLTKLDHPYIIQIHSILQRXPKNFIFMRFAE 227

Query: 155 GGSMLDIIKYIVNRGEHKNGVLEEAIIATILKEVLEGLDYLHRNGQIHRDLKAGNILLGE 214
            G +L  I+ +        G ++E        ++   L+YLH     HRDLK  NILL  
Sbjct: 228 RGDLLTYIQEV--------GFVKEKQAKIWFYQMTTALNYLHSYDVAHRDLKCENILLSS 383

Query: 215 DGSVQIADFGVSAFLATGGDVTRNKVRKTFVGTPCWMAPEVMEQVRGYDFKADMWSFG 272
             +V++ADFG +    T  +     + +T+ G+  + APE++         AD WS G
Sbjct: 384 HFNVKLADFGFACACIT--ESGEKYMSRTYCGSAAYAAPEIVYGAPYAPKVADAWSLG 551
>04591
          Length = 1117

 Score = 63.9 bits (154), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 49/174 (28%), Positives = 80/174 (45%), Gaps = 14/174 (8%)
 Frame = -2

Query: 119  LKEIQAMSQCSHPNVVTY----------YTSFVVKDELWLVMKL----LSGGSMLDIIKY 164
            L+EI+ + Q  H NVV            Y  +  K   +L+ +     L+G  +L+ ++ 
Sbjct: 1077 LREIKILQQLEHENVVQLQEICHTQAGPYNRY--KSTFYLIFEYCDYDLAG--LLNNLRV 910

Query: 165  IVNRGEHKNGVLEEAIIATILKEVLEGLDYLHRNGQIHRDLKAGNILLGEDGSVQIADFG 224
              +  + KN          ++ ++L GL Y+H    +HRD+KA NILL  DG +++ADFG
Sbjct: 909  KFSLADKKN----------LMSQLLNGLFYIHTKQILHRDIKAANILLTRDGVLKLADFG 760

Query: 225  VSAFLATGGDVTRNKVRKTFVGTPCWMAPEVMEQVRGYDFKADMWSFGITAIEL 278
            +S        +T   V      T  +  PE++   R Y  + DMW  G    E+
Sbjct: 759  LSRPWVKSKRLTNRVV------TLWYRPPELLLGEREYGPEIDMWGVGCIMAEM 616
>01966
          Length = 1735

 Score = 63.5 bits (153), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 38/140 (27%), Positives = 76/140 (54%), Gaps = 3/140 (2%)
 Frame = -1

Query: 94   CKPRQ--ERVAIKRINLEKCQTSM-DELLKEIQAMSQCSHPNVVTYYTSFVVKDELWLVM 150
            C+ R    ++A+K+I L   +  +    ++EI  + +  H N+V      +  + L+LV 
Sbjct: 1654 CRHRATGRKLAMKKIRLRGSEDGVPSSAIREIAMLRELRHTNIVCLEDVIMEDERLFLVF 1475

Query: 151  KLLSGGSMLDIIKYIVNRGEHKNGVLEEAIIATILKEVLEGLDYLHRNGQIHRDLKAGNI 210
            + LS    +D+  YI    E    VL+  ++ + + +++ G+++ H+   +HRDLK  N+
Sbjct: 1474 EFLS----MDLKMYIDKFPE--GVVLDRRLVKSYVFQIVTGINFCHQRRIVHRDLKPQNL 1313

Query: 211  LLGEDGSVQIADFGVSAFLA 230
            L+   G+++IADFG++   A
Sbjct: 1312 LINHTGAIKIADFGMARTFA 1253
>12672
          Length = 773

 Score = 62.8 bits (151), Expect = 4e-10,   Method: Compositional matrix adjust.
 Identities = 34/101 (33%), Positives = 54/101 (53%), Gaps = 3/101 (2%)
 Frame = +3

Query: 184 ILKEVLEGLDYLHRNGQIHRDLKAGNILLGEDGSVQIADFGVSAFLATG-GDVTRNKVRK 242
           I+K    G+ YL+ NG +HRD+K  NILL  + + ++ DF       +G G   +N    
Sbjct: 6   IVKGTASGIQYLNDNGHVHRDIKTANILLDSEYTAKVGDFATVVSAPSGEGKTVQNA--S 179

Query: 243 TFVGTPCWMAPEVMEQVRGYDF--KADMWSFGITAIELATG 281
             +GT  ++APE +     +D   K D +SFG+  +E+ TG
Sbjct: 180 VVIGTAAYLAPEAIH----FDVSTKLDSYSFGVVLLEVITG 290
>19301
          Length = 712

 Score = 62.4 bits (150), Expect = 4e-10,   Method: Compositional matrix adjust.
 Identities = 42/160 (26%), Positives = 80/160 (50%), Gaps = 1/160 (0%)
 Frame = +2

Query: 68  WPICRDAYELQEVIGSGAT-AVVQAALCKPRQERVAIKRINLEKCQTSMDELLKEIQAMS 126
           W I  ++    E +GSGA  AV    LC    E VA+K++         D    +I+ + 
Sbjct: 290 WEIPFESITDLEWLGSGAQGAVFLGKLCA---EEVAVKKVR--------DIKETDIRNLR 436

Query: 127 QCSHPNVVTYYTSFVVKDELWLVMKLLSGGSMLDIIKYIVNRGEHKNGVLEEAIIATILK 186
           + +HPN++++           ++M+    G + ++++            +  A++    K
Sbjct: 437 KLNHPNIISFKGVCTQAPCYCIIMEYCPYGQLYEVLR--------DGKEIPPALVLDWSK 592

Query: 187 EVLEGLDYLHRNGQIHRDLKAGNILLGEDGSVQIADFGVS 226
           ++  G++YLH +  IHRDLK+ N+L+ ++  V+I+DFG S
Sbjct: 593 QIASGMNYLHSHKIIHRDLKSPNVLVAKNDVVKISDFGTS 712
>29581
          Length = 1278

 Score = 62.0 bits (149), Expect = 6e-10,   Method: Compositional matrix adjust.
 Identities = 50/153 (32%), Positives = 73/153 (47%), Gaps = 4/153 (2%)
 Frame = -2

Query: 130  HPNVVTYYTSFVVK--DELWLVMKLLSG--GSMLDIIKYIVNRGEHKNGVLEEAIIATIL 185
            H N+V      V K  D L+LVM+       S+LD          +      E+ +  I+
Sbjct: 1178 HQNIVQLQEVVVGKSLDSLFLVMEYCEQDLASLLD----------NMPAPFSESQVKCIV 1029

Query: 186  KEVLEGLDYLHRNGQIHRDLKAGNILLGEDGSVQIADFGVSAFLATGGDVTRNKVRKTFV 245
             ++L+GL YLH    IHRDLK  N+L+ + G V+IADFG++      G   +    K  V
Sbjct: 1028 LQLLKGLRYLHEAFIIHRDLKVSNLLMTDKGCVKIADFGLA---RNYGKPQKPMTPK--V 864

Query: 246  GTPCWMAPEVMEQVRGYDFKADMWSFGITAIEL 278
             T  + APE++   + +    DMWS G    EL
Sbjct: 863  VTLWYRAPELLFGSKTHSTAIDMWSAGCILGEL 765
>27546
          Length = 426

 Score = 61.6 bits (148), Expect = 9e-10,   Method: Composition-based stats.
 Identities = 36/118 (30%), Positives = 63/118 (53%), Gaps = 2/118 (1%)
 Frame = -1

Query: 120 KEIQAMSQCSHPNVVTYYTSFVVKDELWLVMKLLSGGSMLDIIKYIVNRGEHKNGVLEEA 179
           +E++ +++  HPN++  ++      ++++ M+    G ML  IK        K G ++EA
Sbjct: 333 RELEILTRLDHPNIIQIHSILQRGPKIFIFMRYAEKGDMLSHIK--------KTGPIDEA 178

Query: 180 IIATILKEVLEGLDYLHRNGQIHRDLKAGNILLGEDGSVQIADFGVSAFL--ATGGDV 235
                  ++ + L YLH +   HRDLK  NILL +  +V+IADFG + +   A G D+
Sbjct: 177 QTKVWFFQMAKALQYLHSHDIAHRDLKCENILLSKRLNVKIADFGFARYCRDAAGMDL 4
>19761
          Length = 473

 Score = 60.8 bits (146), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 47/160 (29%), Positives = 77/160 (48%), Gaps = 2/160 (1%)
 Frame = -3

Query: 176 LEEAIIATILKEVLEGLDYLHRNGQI--HRDLKAGNILLGEDGSVQIADFGVSAFLATGG 233
           L E +I   L +    L+Y+H +  +  HRDLK  NI + E G V++ D G++  L    
Sbjct: 432 LPERLIVCWLMQTASALNYMHTHTPVILHRDLKPQNIYVTEKGDVRLGDLGLARKLTGPA 253

Query: 234 DVTRNKVRKTFVGTPCWMAPEVMEQVRGYDFKADMWSFGITAIELATGAAPYHKYPPMKV 293
           D   ++     VGT  +++PE++ Q + Y+ K+D+WS G    ++ TG     +   M V
Sbjct: 252 DFATSQ-----VGTIMYLSPEILSQ-QPYNSKSDIWSLGCVFYDI-TGKKGSDE---MGV 103

Query: 294 LMLTLQNDPPTLETGVEDKEMMKKYGKSFRKLLSLCLQKD 333
           + L +Q        G     +   Y + FR  +S  L KD
Sbjct: 102 MFLLVQ------VMGGRKLPLPDHYSQEFRDTISRMLTKD 1
>28157
          Length = 400

 Score = 58.9 bits (141), Expect = 5e-09,   Method: Compositional matrix adjust.
 Identities = 45/139 (32%), Positives = 77/139 (55%), Gaps = 8/139 (5%)
 Frame = +3

Query: 101 VAIKRINLEKCQTSMDELLKEIQAMSQCSHPNVVTYYTSFVVKDE-LWLVMKLLSGGSML 159
           VA+KRI  E+ + S    ++E++ +S+ SHPN+V  Y +   +D  + LVM+   GGS+ 
Sbjct: 9   VAVKRIESEQEKKS---FMQELKQLSRVSHPNIVCLYGA--CRDHPVCLVMEYAEGGSLY 173

Query: 160 DIIKYIVNRGEHKNGVLEEAIIATILKEVLE---GLDYLH---RNGQIHRDLKAGNILLG 213
           +++        H +G   +   A  +  +L+   G++YLH       IHRDLK  N+LL 
Sbjct: 174 NVL--------HGSGPQPQYTAAHAMNWLLQCALGVEYLHGMKPKALIHRDLKPPNLLLI 329

Query: 214 EDGS-VQIADFGVSAFLAT 231
           + G+ ++I DFG +  + T
Sbjct: 330 QCGTKLKICDFGTACDIHT 386
>04138
          Length = 800

 Score = 57.0 bits (136), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 54/185 (29%), Positives = 75/185 (40%), Gaps = 25/185 (13%)
 Frame = +1

Query: 190 EGLDYLHRNGQIHRDLKAGNILLGEDGSVQIADFGVS-AFLATGGDVTRNKVRKTFVGTP 248
           E L Y+HRN  +HRD+KA NIL+ + G +++ADFG++ AF        R   R   V T 
Sbjct: 46  ERLYYIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNR---VVTL 216

Query: 249 CWMAPEVMEQVRGYDFKADMWSFGITAIELATGAAPYHKYPPMKVLMLTLQ---NDPPTL 305
            +  PE++   R Y    D W  G    E+ T             L L  Q   +  P +
Sbjct: 217 WYRPPELLLGDRNYSTAIDQWGAGCIMAEMWTRNPIMQGTTEQNQLTLITQLCGSITPEV 396

Query: 306 ETGVEDKEMMKKYGKSF---RK------------------LLSLCLQKDPSKRPTAAELL 344
             GV    M  +   +    RK                  L    L+ DPS+R +A E L
Sbjct: 397 WPGVTQLSMYHQIKGALAAGRKNIIRDRFARILKDPYGLDLFERLLKMDPSQRISADEAL 576

Query: 345 KCKFF 349
              FF
Sbjct: 577 NHDFF 591
>14477
          Length = 493

 Score = 55.8 bits (133), Expect = 4e-08,   Method: Compositional matrix adjust.
 Identities = 46/153 (30%), Positives = 78/153 (50%), Gaps = 3/153 (1%)
 Frame = -1

Query: 81  IGSGATAVVQAALCK--PRQERVAIKRI-NLEKCQTSMDELLKEIQAMSQCSHPNVVTYY 137
           +G+G    V   +C+   R+  VAIK + N +   +   EL+KE + M +  H ++V   
Sbjct: 466 LGAGNFGSVMKGVCRLDDREIPVAIKVLKNADLDPSVQSELIKEAEVMKKMDHMHIVRL- 290

Query: 138 TSFVVKDELWLVMKLLSGGSMLDIIKYIVNRGEHKNGVLEEAIIATILKEVLEGLDYLHR 197
                 + + LV++L   G +        N+   KN  L    I  ++ +V +G++YL  
Sbjct: 289 IGLCEGETMMLVLELAKLGPL--------NKFLPKNKHLPLWNILELMWQVSQGMEYLEA 134

Query: 198 NGQIHRDLKAGNILLGEDGSVQIADFGVSAFLA 230
           N  +HRDL A NILL ++   +I+DFG+S  L+
Sbjct: 133 NKFVHRDLAARNILLCDEHFAKISDFGMSKTLS 35
>03508
          Length = 1463

 Score = 55.8 bits (133), Expect = 4e-08,   Method: Compositional matrix adjust.
 Identities = 29/105 (27%), Positives = 52/105 (49%), Gaps = 1/105 (0%)
 Frame = +1

Query: 181 IATILKEVLEGLDYLHRNGQIHRDLKAGNILLG-EDGSVQIADFGVSAFLATGGDVTRNK 239
           I   L E+++ LD+ H  G +HRD+K  N+++  E+  +++ D+G++ F   G +     
Sbjct: 877 IRFYLYELMKALDFCHSMGIMHRDVKPHNVMIDHENKKLRLIDWGLAEFYHPGMEYNVRV 1056

Query: 240 VRKTFVGTPCWMAPEVMEQVRGYDFKADMWSFGITAIELATGAAP 284
             + F G      PE++   + YD+  DMWS G     +     P
Sbjct: 1057ASRYFKG------PELLLDYQMYDYSLDMWSLGCMFASMIFRKEP 1173
>07836
          Length = 1478

 Score = 55.1 bits (131), Expect = 6e-08,   Method: Compositional matrix adjust.
 Identities = 62/223 (27%), Positives = 106/223 (47%), Gaps = 21/223 (9%)
 Frame = -1

Query: 145  ELWLVMKLLSGGSMLDIIKYIVNRGEHKNGVLEEAIIATILKEVLEGLDYLH-------- 196
            +L+L+      GS+ D   Y+++R      VL+ + +  +    + GL +LH        
Sbjct: 1331 QLFLITDYHENGSLHD---YLLSR------VLDSSEMLALAHSAICGLAHLHIEIFGTRG 1179

Query: 197  RNGQIHRDLKAGNILLGEDGSVQIADFGVSA-FLATGG--DVTRNKVRKTFVGTPCWMAP 253
            +    HRD+K+ NIL+ ++G+  IAD G++  +++     DV  N  +    GT  +MAP
Sbjct: 1178 KPAIAHRDIKSKNILVKKNGTCCIADLGLAVRYISESNEVDVAPNPRQ----GTKRYMAP 1011

Query: 254  EVME---QVRGYD-FK-ADMWSFGITAIELAT-----GAAPYHKYPPMKVLMLTLQNDPP 303
            EV+E    V+ +D FK ADM++FG+   E+A      G A  ++ P        L +DP 
Sbjct: 1010 EVLEMLLNVKNFDAFKQADMYAFGLVMWEIARCCVIGGVAEEYQVP----FYNCLPHDP- 846

Query: 304  TLETGVEDKEMMKKYGKSFRKLLSLCLQKDPSKRPTAAELLKC 346
                  ED  ++    K  R  + L  Q+DP  +     + +C
Sbjct: 845  ----SFEDVRLVVSVDK-VRPDIPLRWQEDPIMKVMVKVMCEC 732
>07833
          Length = 1504

 Score = 54.3 bits (129), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 55/231 (23%), Positives = 100/231 (43%), Gaps = 9/231 (3%)
 Frame = -3

Query: 117  ELLKEIQAMSQCSHPNVVTYYTSFVVKDELWLVMKLLSGGSMLDIIKYIVNRGEHKNGVL 176
            + ++E   +   +HPNV+           L L+ + +  GS+ + +      GE    V+
Sbjct: 1481 DFMEEFPRLRIFNHPNVLPVLACCNQPPNLVLISQFMPFGSLYNTL-----HGE-SGIVV 1320

Query: 177  EEAIIATILKEVLEGLDYLHRNGQIHRD--LKAGNILLGED--GSVQIADFGVSAFLATG 232
            ++        ++  G+++LH       +  L + ++++ ED    + +AD+  S F   G
Sbjct: 1319 DQNQSLRFAMDIARGMEFLHSMEPTIPNFLLTSKHVMIDEDLTARINMADYCFS-FHEKG 1143

Query: 233  GDVTRNKVRKTFVGTPCWMAPEVMEQVRGYDFK---ADMWSFGITAIELATGAAPYHKYP 289
                        V +P WMAPE +++ R  D     ADMWSF I   EL T   P+ +  
Sbjct: 1142 K-----------VYSPAWMAPEALQR-RPDDINTRAADMWSFAILMWELETREVPFAELS 999

Query: 290  PMKVLMLTLQNDPPTLETGVEDKEMMKKYGKSFR--KLLSLCLQKDPSKRP 338
             M+V M          +  +E   +    G S    +L+ +C+ ++P KRP
Sbjct: 998  SMEVGM----------KVALEGLRISIPPGISLHMSRLIKICMNEEPGKRP 876
>21210
          Length = 518

 Score = 53.5 bits (127), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 35/111 (31%), Positives = 54/111 (48%), Gaps = 4/111 (3%)
 Frame = +3

Query: 250 WMAPEVME---QVRGYDFKADMWSFGITAIELATGAAPYHKYPPM-KVLMLTLQNDPPTL 305
           +MAPE ++      GYD ++D+WS GIT +ELATG  PY K+  +   L   ++   P L
Sbjct: 18  YMAPERIDPRASSHGYDVRSDVWSLGITLMELATGRFPYRKWVSIFDQLQQVVRGVAPCL 197

Query: 306 ETGVEDKEMMKKYGKSFRKLLSLCLQKDPSKRPTAAELLKCKFFQKAKNRE 356
                       +   F   ++ CL KD  +RP   +LL   F +  + +E
Sbjct: 198 PHD-------GAFSHDFVNFVNKCLTKDEKQRPKYNKLLAHPFVRLYEEQE 329
>21433
          Length = 590

 Score = 52.8 bits (125), Expect = 4e-07,   Method: Compositional matrix adjust.
 Identities = 35/103 (33%), Positives = 52/103 (50%)
 Frame = +2

Query: 182 ATILKEVLEGLDYLHRNGQIHRDLKAGNILLGEDGSVQIADFGVSAFLATGGDVTRNKVR 241
           A  + ++   L+Y H    IHRD+K  N+LLG  G ++IADFG S    +         R
Sbjct: 176 ACYIYQLSSALEYCHYRKVIHRDIKPENLLLGLKGDLKIADFGWSVHAPSSR-------R 334

Query: 242 KTFVGTPCWMAPEVMEQVRGYDFKADMWSFGITAIELATGAAP 284
            T  GT  ++ PE++E  + +D   D+WS G+   E   G  P
Sbjct: 335 TTMCGTLDYLPPEMVEG-KTHDENVDLWSLGVLCYEFLVGTPP 460
>17300
          Length = 480

 Score = 52.0 bits (123), Expect = 7e-07,   Method: Compositional matrix adjust.
 Identities = 35/109 (32%), Positives = 53/109 (48%), Gaps = 2/109 (1%)
 Frame = +1

Query: 188 VLEGLDYLHRNGQIHRDLKAGNILLGEDGSVQIADFGVSAFLATGGDVTRNKVRKTFVGT 247
           +  G+  L   G +HRDL A NIL+ E    ++ADFG+S  + +  D T           
Sbjct: 1   ISSGMGXLADMGYVHRDLAARNILVNEILVCKVADFGLSREIES--DTTEGAYTTKGGKI 174

Query: 248 PC-WMAPEVMEQVRGYDFKADMWSFGITAIE-LATGAAPYHKYPPMKVL 294
           P  W APE +   R +   +D+WSFG+   E ++ G  PY  +    V+
Sbjct: 175 PVRWTAPEAI-AYRKFTSASDVWSFGVVMWEVMSYGERPYWNWSNQDVI 318
>11185
          Length = 473

 Score = 51.6 bits (122), Expect = 7e-07,   Method: Compositional matrix adjust.
 Identities = 43/180 (23%), Positives = 70/180 (38%), Gaps = 17/180 (9%)
 Frame = +1

Query: 187 EVLEGLDYLHRNGQIHRDLKAGNILLGEDGSVQIADFGVSAF-----------LATGGDV 235
            ++ GL Y+H  G +  DL+   +LL   G ++ ADFG+S              A  GD 
Sbjct: 25  HLVTGLHYIHSLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEAGDQ 204

Query: 236 TRNKVRKTFV------GTPCWMAPEVMEQVRGYDFKADMWSFGITAIELATGAAPYHKYP 289
              +  +  +      G+P +MAPEV +        +D+W+ G    E+ +G+       
Sbjct: 205 WNIQSAEEMMKQVPTSGSPTYMAPEVFQGAEP-SIMSDLWALGCVFYEMFSGS------- 360

Query: 290 PMKVLMLTLQNDPPTLETGVEDKEMMKKYGKSFRKLLSLCLQKDPSKRPTAAELLKCKFF 349
                                   +  K    F  LL   LQKD ++R + A L+K  F+
Sbjct: 361 -----------------------RLSAKPSPEFLNLLESLLQKDSTRRLSWASLVKHAFW 471
>17253
          Length = 483

 Score = 51.2 bits (121), Expect = 1e-06,   Method: Composition-based stats.
 Identities = 36/143 (25%), Positives = 64/143 (44%), Gaps = 6/143 (4%)
 Frame = -1

Query: 99  ERVAIKRINLEKCQTSMDELLKEIQAMSQC-SHPNVVTYYTSFVVKDELWLVMKLLSGGS 157
           + VA+K  N         E L+E+  M +   HPNVV++     + D   ++M+    G 
Sbjct: 465 DTVAVKTHNEAATDAEKSEFLRELSIMRKLPRHPNVVSFMGCCTMSDPALILMEFCCHGD 286

Query: 158 MLDIIK-----YIVNRGEHKNGVLEEAIIATILKEVLEGLDYLHRNGQIHRDLKAGNILL 212
           +L  ++       V      N +      +  L  V  G+ ++  N  +HRD+ A N+L+
Sbjct: 285 LLSFLRKRRPDRTVFLTSTANDLTARDFFSFAL-HVARGMAHVANNKIVHRDVAARNVLI 109

Query: 213 GEDGSVQIADFGVSAFLATGGDV 235
            E    +++DFG+S  +    DV
Sbjct: 108 SERNVCKVSDFGLSRRVGDQNDV 40
>12786
          Length = 460

 Score = 50.4 bits (119), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 40/143 (27%), Positives = 67/143 (46%), Gaps = 20/143 (13%)
 Frame = -3

Query: 164 YIVNRGEHKNGVLEEAIIATILKEVLEGLDYLHRNGQIHRDLKAGNILLGEDGSVQIADF 223
           +   R + + G L+  +I    +E+L  +  LH  G IH DLK  N +L   G++++ DF
Sbjct: 452 FFSARAKQEQG-LDRMMIKFYWREMLRAVKALHNEGVIHSDLKPANFMLVA-GNLKLIDF 279

Query: 224 GVSAFLATGGDVTRNKVRKTFVGTPCWMAPEV------------MEQVRGYDFK------ 265
           G++  L    D T + ++ + VGTP +M+PE             ME+  G+  K      
Sbjct: 278 GIANTLQQ--DKT-SVLKDSRVGTPSYMSPEAIMAACDDSADDSMEE-DGHRTKPKYKVG 111

Query: 266 --ADMWSFGITAIELATGAAPYH 286
             +D+WS G     +  G  P+ 
Sbjct: 110 VRSDVWSLGCILYNMVYGRTPFQ 42
>18996
          Length = 491

 Score = 49.7 bits (117), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 38/147 (25%), Positives = 68/147 (46%), Gaps = 2/147 (1%)
 Frame = +2

Query: 201 IHRDLKAGNILLGEDGSVQIADFGVSAFLATGGDVTRNKVRKTFVGTPCWMAPEVMEQVR 260
           IHRDL A NIL+ +   V+I+DFG++ F    G       R   +    W +PE +E  +
Sbjct: 2   IHRDLAARNILV-DRSCVKISDFGLAQFANADGYYYGISQRDIPIK---WYSPEAIETCK 169

Query: 261 GYDFKADMWSFGITAIELATGAAPYHKYPPMKVLMLTLQNDPPTLETG--VEDKEMMKKY 318
            +   +D+WS+G+T  E+ +     +  P   +      N    L  G  +   E+   +
Sbjct: 170 -FSSYSDVWSYGVTLFEMFSRGEIPNLLPGHDLTQEEFLN---RLRKGERLPKPELCSDF 337

Query: 319 GKSFRKLLSLCLQKDPSKRPTAAELLK 345
              + +L+  C  + P  RPT  ++++
Sbjct: 338 --VYSELMRPCWHEMPKSRPTFHQIIQ 412
>02638
          Length = 1490

 Score = 48.5 bits (114), Expect = 7e-06,   Method: Compositional matrix adjust.
 Identities = 31/108 (28%), Positives = 50/108 (46%)
 Frame = +1

Query: 244 FVGTPCWMAPEVMEQVRGYDFKADMWSFGITAIELATGAAPYHKYPPMKVLMLTLQNDPP 303
            +GT  +MAPEV+     Y    D+WS G   IE+ T   P++ +     L L  +    
Sbjct: 16  LLGTIAFMAPEVLRG-ESYGRACDVWSVGCVMIEMCTCRPPWNSHDISNHLALIFK---- 180

Query: 304 TLETGVEDKEMMKKYGKSFRKLLSLCLQKDPSKRPTAAELLKCKFFQK 351
            + + V+   + +      R L+  CL++D   RP+A +LL    F K
Sbjct: 181 -IASSVDPPPIPENMSPPVRDLMLRCLEQDSDFRPSAKDLLMHPLFTK 321
>25019
          Length = 730

 Score = 45.4 bits (106), Expect = 6e-05,   Method: Compositional matrix adjust.
 Identities = 25/64 (39%), Positives = 36/64 (56%)
 Frame = +3

Query: 209 NILLGEDGSVQIADFGVSAFLATGGDVTRNKVRKTFVGTPCWMAPEVMEQVRGYDFKADM 268
           N+LL +DG V++ DFG+     TG      +V  TF GT  +MAPE++ +  G+    D 
Sbjct: 264 NVLLDKDGHVKLTDFGLCKEAITG-----TRVTHTFCGTIEYMAPEILTRT-GHGKAVDW 425

Query: 269 WSFG 272
           WS G
Sbjct: 426 WSLG 437
>20640
          Length = 1492

 Score = 45.1 bits (105), Expect = 7e-05,   Method: Compositional matrix adjust.
 Identities = 41/162 (25%), Positives = 64/162 (39%), Gaps = 15/162 (9%)
 Frame = +1

Query: 199 GQIHRDLKAGNILLGEDGSVQIADFGVSAFLAT-----GGDVTRNKVRKTFVGTPCWMAP 253
           G +HRDL   N L+G D  V+I+DFG++  + +     G +     +R        WM  
Sbjct: 4   GYVHRDLATRNCLVGHDLVVKISDFGLARSVHSVDYYRGSEHDAIPIR--------WMPL 159

Query: 254 EVMEQVRGYDFKADMWSFGITAIEL-ATGAAPYHKYPPM---------KVLMLTLQNDPP 303
           E +     +  ++D+WSFG+   E+ A    PY+              KVL    +  PP
Sbjct: 160 EAI-LYNKFSTQSDVWSFGVVLWEIFAFALQPYYGLTHEEVVRFVKEGKVLACPERTPPP 336

Query: 304 TLETGVEDKEMMKKYGKSFRKLLSLCLQKDPSKRPTAAELLK 345
             E                  L+  C  + P+ RP+   L K
Sbjct: 337 MYE------------------LMKQCWHRRPATRPSFHTLHK 408
>37063
          Length = 455

 Score = 44.3 bits (103), Expect = 1e-04,   Method: Composition-based stats.
 Identities = 30/76 (39%), Positives = 42/76 (55%), Gaps = 7/76 (9%)
 Frame = -2

Query: 205 LKAGNIL---LGEDGSVQIADFGVSAFLATGGDVTRNKVRKTFVGTPCWMAPEVMEQVRG 261
           LK  NIL   L E   ++I DF +++ +   GD T+     T VG+  +MAPEV++   G
Sbjct: 454 LKPENILCEHLDEVVPLKICDFDLASGINCDGDGTKTPELLTPVGSAEYMAPEVVDAWVG 275

Query: 262 ----YDFKADMWSFGI 273
               YD + DMWS GI
Sbjct: 274 ESFSYDKRCDMWSLGI 227
>16708
          Length = 1397

 Score = 43.1 bits (100), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 50/224 (22%), Positives = 92/224 (41%), Gaps = 12/224 (5%)
 Frame = -1

Query: 79   EVIGSGATAVVQAALCKPRQERVAIKRINLEKCQTSMDEL--LKEIQAMSQCSHPNVVTY 136
            +V+G G    V  A      E+ A+K   L  C  S+DE+  L  I+     +   +   
Sbjct: 1385 QVLGKGVFGKVYEARLLSTHEKAALKTSIL--CHHSLDEVEALGRIEGGFYLA--QMFGA 1218

Query: 137  YTSFVVKDELWLVMKLLSGGSMLDIIKYIVNRGEHKNGVLEEAIIATILKEVLEGLDYLH 196
            + + +   ++ +++     G + ++  +  N+ E        A++  I  + +  L+++H
Sbjct: 1217 WVTCLPFPKMNILLHFYEMGPLCNVYAHYKNK-EMPIRWSNPAMVCCIAGQXVCALEHIH 1041

Query: 197  RNGQIHRDLKAGNILLGEDGSVQIADFGVS-------AFLATGGDVTRNKVRKTFVGTPC 249
              G +H D+KA N+L+   G+ ++ D+G++       A   T      NK R  +   P 
Sbjct: 1040 ELGVVHMDVKADNVLVDAHGNCKLTDYGIAQLYKVYPAPTETHSSGCTNK-RTFYTRPPA 864

Query: 250  WMAPEVMEQVRGYDFKADMWSFGITAIELATGAAPYHKY---PP 290
             M P       G     D +  G     L TGA   H +   PP
Sbjct: 863  TMTPSERFSEEGDGIGTDYFRLGQMLWTL-TGAVLLHVWVSRPP 735
>17516
          Length = 453

 Score = 41.6 bits (96), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 20/42 (47%), Positives = 25/42 (59%)
 Frame = -3

Query: 240 VRKTFVGTPCWMAPEVMEQVRGYDFKADMWSFGITAIELATG 281
           +  T  GTP +MAPEV+ Q   YD KAD++S  I   EL  G
Sbjct: 451 IAGTLAGTPVYMAPEVLLQKGQYDMKADVYSLAIILWELWYG 326
>18663
          Length = 600

 Score = 40.8 bits (94), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 18/45 (40%), Positives = 27/45 (60%), Gaps = 2/45 (4%)
 Frame = +2

Query: 243 TFVGTPCWMAPEVMEQVRG--YDFKADMWSFGITAIELATGAAPY 285
           TF GTP ++APE++   RG  Y F  D W+ G+   E+  G +P+
Sbjct: 5   TFCGTPNYIAPEIL---RGEDYGFSVDWWALGVLLYEMLAGRSPF 130
>29590
          Length = 320

 Score = 40.4 bits (93), Expect = 0.002,   Method: Composition-based stats.
 Identities = 19/64 (29%), Positives = 33/64 (51%)
 Frame = +3

Query: 222 DFGVSAFLATGGDVTRNKVRKTFVGTPCWMAPEVMEQVRGYDFKADMWSFGITAIELATG 281
           D G +    TG D+      +  +GTP ++APEV++       + DMWS G+ +  + T 
Sbjct: 6   DLGFACLTNTGEDI------RDIIGTPDYVAPEVLD-YEPLSIQTDMWSLGVLSYVMLTA 164

Query: 282 AAPY 285
            +P+
Sbjct: 165 CSPF 176
>31489
          Length = 329

 Score = 37.4 bits (85), Expect = 0.017,   Method: Composition-based stats.
 Identities = 18/54 (33%), Positives = 31/54 (57%)
 Frame = +3

Query: 158 MLDIIKYIVNRGEHKNGVLEEAIIATILKEVLEGLDYLHRNGQIHRDLKAGNIL 211
           + D+++  ++R  + +  L E  I   L ++L GL Y+H    +HRDLK  N+L
Sbjct: 102 VFDLMESDLHRIIYSDQPLTEEHIRYFLYQILRGLKYIHSANVVHRDLKPSNLL 263
>38560
          Length = 479

 Score = 37.0 bits (84), Expect = 0.023,   Method: Compositional matrix adjust.
 Identities = 31/112 (27%), Positives = 46/112 (41%)
 Frame = -3

Query: 243 TFVGTPCWMAPEVMEQVRGYDFKADMWSFGITAIELATGAAPYHKYPPMKVLMLTLQNDP 302
           T  G+P + APE++  +     +AD+WS G+    L  G  P+      K   L  +N  
Sbjct: 408 TCCGSPAYAAPELISGLEYLGSEADIWSMGVLLYALLCGYLPFDD---EKXSHL*QKNQK 238

Query: 303 PTLETGVEDKEMMKKYGKSFRKLLSLCLQKDPSKRPTAAELLKCKFFQKAKN 354
                     E+ +   +   KLL   LQ DPS R T   LL   +  +  N
Sbjct: 237 -------RKDEVPEWLSEDTTKLLEGMLQTDPSHRITIRRLLDHHWLNQGFN 103
>21800
          Length = 855

 Score = 37.0 bits (84), Expect = 0.023,   Method: Compositional matrix adjust.
 Identities = 21/49 (42%), Positives = 30/49 (61%), Gaps = 1/49 (2%)
 Frame = +2

Query: 181 IATILKEVLEGLDYLH-RNGQIHRDLKAGNILLGEDGSVQIADFGVSAF 228
           +  I+++VLEGL+YLH +   IH D+K  NIL+  D +  I    V AF
Sbjct: 638 VKLIIRQVLEGLNYLHAKCNIIHTDIKPENILICVDDN-YIRKLAVDAF 781
>18481
          Length = 437

 Score = 36.6 bits (83), Expect = 0.028,   Method: Composition-based stats.
 Identities = 32/100 (32%), Positives = 47/100 (47%), Gaps = 3/100 (3%)
 Frame = -1

Query: 130 HPNVVTYYTSFVVKDELWLVMKLLSGGSMLDIIKYIVNRGEHKNGVLEEAIIATILKEVL 189
           HP + T Y     K    LVM+LL G S+ ++      R   K        I  +  ++L
Sbjct: 320 HPGLPTMYHYGTEKHFNALVMELL-GPSLEELFVICKRRFTLKT-------ILMVSDQLL 165

Query: 190 EGLDYLHRNGQIHRDLKAGNILLG---EDGSVQIADFGVS 226
             L+++H+   IHRDLK  N L+G       + I DFG+S
Sbjct: 164 SRLEFIHQKCFIHRDLKPDNFLMGLGRHCHRLYIIDFGLS 45
>11404
          Length = 563

 Score = 34.7 bits (78), Expect = 0.093,   Method: Compositional matrix adjust.
 Identities = 41/146 (28%), Positives = 68/146 (46%), Gaps = 6/146 (4%)
 Frame = +1

Query: 73  DAYELQEVIGSGATAVVQAALCKPRQERVAIKRINLEKCQTSMDEL-LKEIQAMSQCSHP 131
           D YE+  +IG G+   V  A      E+VAIK I  +K   +  ++ +K ++ M++    
Sbjct: 139 DRYEIDSLIGKGSFGQVVKAYDHTDNEQVAIKIIKNKKPFLNQAQIEVKLLEMMNRHDTD 318

Query: 132 N---VVTYYTSFVVKDELWLVMKLLSGGSMLDIIKYIVNRGEHKNGVLEEAIIATILKEV 188
           N   +V     F+ +  L LV +LLS  ++ D+++    RG   N      +     +++
Sbjct: 319 NKYYIVRLKRHFMFRSHLCLVFELLS-YNLYDLLRNTNFRGVSLN------LTRKFAQQL 477

Query: 189 LEGLDYLH--RNGQIHRDLKAGNILL 212
              L +L       IH DLK  NILL
Sbjct: 478 CTALLFLATPEMSIIHCDLKPENILL 555
>26009
          Length = 886

 Score = 34.7 bits (78), Expect = 0.10,   Method: Compositional matrix adjust.
 Identities = 10/30 (33%), Positives = 22/30 (73%)
 Frame = +3

Query: 183 TILKEVLEGLDYLHRNGQIHRDLKAGNILL 212
           +++K+++  LD++H    +HRD+K  N+L+
Sbjct: 723 SVMKQLVSALDFMHSKQLVHRDIKPENVLI 812
>32359
          Length = 928

 Score = 34.3 bits (77), Expect = 0.15,   Method: Compositional matrix adjust.
 Identities = 27/83 (32%), Positives = 44/83 (53%), Gaps = 4/83 (4%)
 Frame = -1

Query: 74  AYELQEVIGSGATAVVQAALCKPRQERVAIKRINLEKCQTSMDELLKEIQAMSQCSHPNV 133
           +Y   +VIG+G+  VV  A      E VAIK++  +K   +     +E+Q M +  H N+
Sbjct: 427 SYTDAKVIGNGSFGVVYQAKLVDTSELVAIKKVLQDKRFKN-----RELQIMRKLEHQNI 263

Query: 134 VT----YYTSFVVKDELWLVMKL 152
           V     +Y+S   KDE++L + L
Sbjct: 262 VKLKFFFYSSGEKKDEVFLNLVL 194
>01106
          Length = 878

 Score = 33.9 bits (76), Expect = 0.15,   Method: Compositional matrix adjust.
 Identities = 19/49 (38%), Positives = 28/49 (57%), Gaps = 1/49 (2%)
 Frame = +3

Query: 181 IATILKEVLEGLDYLHRNGQ-IHRDLKAGNILLGEDGSVQIADFGVSAF 228
           +  I+++VLEGL Y+H   + IH D+K  NIL+  D +  I      AF
Sbjct: 651 VKLIIRQVLEGLSYMHAKCRIIHTDIKPENILICVDETY-IRKLAADAF 794
>17637
          Length = 447

 Score = 33.9 bits (76), Expect = 0.16,   Method: Composition-based stats.
 Identities = 24/101 (23%), Positives = 48/101 (47%), Gaps = 4/101 (3%)
 Frame = +1

Query: 250 WMAPEVMEQVRGYDFKADMWSFGITAIELAT-GAAPYHKYPPMKVLMLTLQNDPPTLETG 308
           W++ E +++   Y+  +D+WSFG+   E+ T G  PY +             DP  +E  
Sbjct: 115 WLSLEALQKSH-YNEGSDVWSFGVLMWEMCTLGKLPYAEI------------DPYEMEHY 255

Query: 309 VEDKEMMKKYGKSFRKLLSL---CLQKDPSKRPTAAELLKC 346
           ++D   + +      +L ++   C    P++RP+ ++L  C
Sbjct: 256 LKDGYRLAQPFNCPDELFTIMAYCWASMPAERPSFSQLQIC 378
>11541
          Length = 1193

 Score = 33.9 bits (76), Expect = 0.17,   Method: Compositional matrix adjust.
 Identities = 14/17 (82%), Positives = 15/17 (88%)
 Frame = +1

Query: 328 LCLQKDPSKRPTAAELL 344
           LC+QKDP KRPTA ELL
Sbjct: 1   LCIQKDPDKRPTARELL 51
>32000
          Length = 644

 Score = 33.1 bits (74), Expect = 0.29,   Method: Compositional matrix adjust.
 Identities = 21/68 (30%), Positives = 32/68 (47%)
 Frame = -1

Query: 216 GSVQIADFGVSAFLATGGDVTRNKVRKTFVGTPCWMAPEVMEQVRGYDFKADMWSFGITA 275
             ++IADFG++      G   R    +  V T  + APE++   R Y    D+WS G   
Sbjct: 578 AKMKIADFGLARVF---GLPVRTYTHE--VITLWYRAPEILLGCRFYSVPVDIWSLGCIF 414

Query: 276 IELATGAA 283
           +E+ T  A
Sbjct: 413 VEMMTRRA 390
>11342
          Length = 1202

 Score = 32.0 bits (71), Expect = 0.60,   Method: Compositional matrix adjust.
 Identities = 13/34 (38%), Positives = 20/34 (58%)
 Frame = -2

Query: 115  MDELLKEIQAMSQCSHPNVVTYYTSFVVKDELWL 148
            M + L EI  + +  H  + +++TSFVV   LWL
Sbjct: 1084 MTKTLXEINCLFKRCHHRLTSFFTSFVVSRSLWL 983
>32957
          Length = 645

 Score = 32.0 bits (71), Expect = 0.64,   Method: Compositional matrix adjust.
 Identities = 18/45 (40%), Positives = 23/45 (51%)
 Frame = +3

Query: 242 KTFVGTPCWMAPEVMEQVRGYDFKADMWSFGITAIELATGAAPYH 286
           +TF GT  +MAPEV E+ + Y  + D W  GI   EL       H
Sbjct: 39  RTFCGTREYMAPEVHER-KEYGKEVDWWGLGILLHELLAAQIKKH 170
>13305
          Length = 549

 Score = 31.2 bits (69), Expect = 1.0,   Method: Composition-based stats.
 Identities = 27/103 (26%), Positives = 43/103 (41%), Gaps = 1/103 (0%)
 Frame = +2

Query: 250 WMAPEVMEQVRGYDFKADMWSFGITAIELAT-GAAPYHKYPPMKVLMLTLQNDPPTLETG 308
           WMA E +     Y  ++D+WSFG+   E+ T G  PY      ++           L+ G
Sbjct: 23  WMAVESLFN-NTYTTQSDVWSFGVVLWEIFTLGGTPYSSTDTQQLFAF--------LKDG 175

Query: 309 VEDKEMMKKYGKSFRKLLSLCLQKDPSKRPTAAELLKCKFFQK 351
              K        ++  +L  C  ++  +RPT  EL  C   Q+
Sbjct: 176 YRLKRPKLCDQNTYAMMLQ-CWNENAQRRPTFPEL--CGRLQR 295
>16350
          Length = 1108

 Score = 31.2 bits (69), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 18/60 (30%), Positives = 23/60 (38%), Gaps = 13/60 (21%)
 Frame = +2

Query: 235 VTRNKVRKTFVGTPCWMAPEVMEQVR-------------GYDFKADMWSFGITAIELATG 281
            T   V+   +G  CW      E ++             GY   AD+WS    A ELATG
Sbjct: 341 CTDFPVKIADLGNACWTYHHFTEDIQTRQYRCLEVLIGAGYGTPADIWSTACMAFELATG 520
>03106
          Length = 2384

 Score = 29.3 bits (64), Expect = 3.9,   Method: Compositional matrix adjust.
 Identities = 23/85 (27%), Positives = 43/85 (50%)
 Frame = +2

Query: 256 MEQVRGYDFKADMWSFGITAIELATGAAPYHKYPPMKVLMLTLQNDPPTLETGVEDKEMM 315
           +E V  Y  KAD+W+ G  A E+   + P+  Y  +     + Q+D P+L     +  + 
Sbjct: 2   LESVLDYS-KADVWAAGAVAYEIFGASNPF--YSRLDSACYS-QHDLPSLPGDTPEGVV- 166

Query: 316 KKYGKSFRKLLSLCLQKDPSKRPTA 340
                   +L++  L++DP++RP+A
Sbjct: 167 --------RLVTSMLERDPAQRPSA 217
>05356
          Length = 2339

 Score = 28.5 bits (62), Expect = 8.0,   Method: Compositional matrix adjust.
 Identities = 14/26 (53%), Positives = 16/26 (61%)
 Frame = -3

Query: 504  DGHDVVIVAANLQKIVDDPKALKTLT 529
            D HD+V+VA  L K  D P A  TLT
Sbjct: 1128 DDHDLVLVAVMLSKXADFPPATITLT 1051
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|9910164|ref|NP_064362.1| doublecortin-like kinase 1
isoform 1 [Mus musculus]
         (756 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

15910                                                                 160   2e-39
14591                                                                 150   2e-36
01392                                                                 133   3e-31
12721                                                                 110   2e-24
13592                                                                 103   3e-22
21079                                                                 103   4e-22
14420                                                                 102   4e-22
09606                                                                 100   2e-21
30755                                                                 100   3e-21
01707                                                                  99   4e-21
03240                                                                  99   5e-21
17975                                                                  98   2e-20
14126                                                                  97   2e-20
01060                                                                  96   5e-20
00300                                                                  92   1e-18
06405                                                                  89   5e-18
18921                                                                  89   9e-18
02841                                                                  89   9e-18
18484                                                                  87   3e-17
13066                                                                  85   9e-17
21433                                                                  67   2e-15
01718                                                                  80   3e-15
31885                                                                  80   3e-15
01966                                                                  69   4e-13
00486                                                                  72   7e-13
19761                                                                  72   8e-13
27405                                                                  72   1e-12
11780                                                                  72   1e-12
26711                                                                  71   2e-12
29581                                                                  67   2e-11
28638                                                                  54   2e-11
27546                                                                  67   3e-11
19094                                                                  66   4e-11
38560                                                                  66   5e-11
28157                                                                  64   2e-10
13212                                                                  64   3e-10
09007                                                                  63   4e-10
04591                                                                  62   6e-10
21808                                                                  62   7e-10
01756                                                                  61   1e-09
00392                                                                  61   2e-09
03508                                                                  59   1e-08
36002                                                                  58   1e-08
29590                                                                  47   2e-08
18663                                                                  57   3e-08
12786                                                                  57   3e-08
14116                                                                  56   5e-08
31489                                                                  55   1e-07
04852                                                                  54   2e-07
26560                                                                  54   3e-07
20152                                                                  52   1e-06
07291                                                                  51   2e-06
11185                                                                  51   2e-06
17722                                                                  50   4e-06
19301                                                                  49   6e-06
07940                                                                  49   9e-06
12672                                                                  48   1e-05
21418                                                                  48   2e-05
01106                                                                  48   2e-05
26156                                                                  44   2e-05
20655                                                                  47   3e-05
25019                                                                  46   6e-05
00715                                                                  45   7e-05
04138                                                                  45   1e-04
18401                                                                  45   1e-04
26009                                                                  44   2e-04
11404                                                                  44   2e-04
36481                                                                  44   2e-04
02638                                                                  44   2e-04
17253                                                                  44   2e-04
37602                                                                  42   0.001
29360                                                                  39   0.008
00638                                                                  39   0.008
22005                                                                  39   0.009
17300                                                                  39   0.010
32957                                                                  39   0.011
16708                                                                  38   0.014
17516                                                                  37   0.042
27274                                                                  35   0.089
07836                                                                  35   0.10 
31120                                                                  35   0.11 
33586                                                                  34   0.21 
21210                                                                  33   0.31 
21800                                                                  32   0.78 
18481                                                                  32   0.79 
20513                                                                  32   1.0  
17806                                                                  31   1.6  
16350                                                                  31   1.8  
16877                                                                  30   2.9  
09826                                                                  30   3.0  
>15910
          Length = 1361

 Score =  160 bits (405), Expect = 2e-39,   Method: Compositional matrix adjust.
 Identities = 80/222 (36%), Positives = 127/222 (57%), Gaps = 2/222 (0%)
 Frame = +2

Query: 488 DLFDAITSTSKYTERDASGMLYNLASAIKYLHSLNIVHRDIKPENLLVYEHQDGSKSLKL 547
           +LFD I +  +YTE+DA+  + ++   ++Y+H+  +VHRD+KPENLL YE       LKL
Sbjct: 422 ELFDRIVTRGQYTEKDAARAISDILHGVQYIHANGVVHRDLKPENLL-YECMTDDSKLKL 598

Query: 548 GDFGLATIVDGP--LYTVCGTPTYVAPEIIAETGYGLKVDIWAAGVITYILLCGFPPFRG 605
            DFGL+ I++    + TVCGTP Y APE++    Y   VD+W+ GVI YILLCG+ PF  
Sbjct: 599 ADFGLSRIIEPEVQMSTVCGTPGYCAPEVLKGDKYTPSVDMWSVGVIAYILLCGYEPFFA 778

Query: 606 SGDDQEVLFDQILMGQVDFPSPYWDNVSDSAKELINMMLLVNVDQRFSAVQVLEHPWVND 665
             + +  ++ +I+ G+  F   YW  +S++AK+++  +L+++  +R +A + L  PWV  
Sbjct: 779 ENEFE--MYRKIIKGEYKFDEEYWSEISENAKDVVRKLLVIDPKKRLTATEALRLPWVK- 949

Query: 666 DGLPENEHQLSVAGKIKKHFNTGPKPSSTAAGVSVIATTALD 707
            G+      + +     K FN   K       + VIA    D
Sbjct: 950 -GVATKTTNMEITMNKLKEFNARRKLKCATDAMLVIAKATTD 1072
>14591
          Length = 1324

 Score =  150 bits (379), Expect = 2e-36,   Method: Compositional matrix adjust.
 Identities = 90/263 (34%), Positives = 137/263 (52%), Gaps = 49/263 (18%)
 Frame = +1

Query: 54  KKAKKVRFYRNGDRYFKGIVYAISPDRFRSFEALLADLTRTLSDNVNLPQGVRTIYTIDG 113
           ++ +KVRF+ NGDR+FKG    I+P R+ +F  LL DLT  L  ++NLP GVR I+T  G
Sbjct: 52  RRPRKVRFFVNGDRFFKGKKLHITPHRYYNFTDLLNDLTGKLPSSINLPYGVRQIFTPVG 231

Query: 114 LKKISSLDQLVEGESYVCGSIEPFKKLEYTKNVNPNWSV-----------NVKTTSASRA 162
            +++S ++ L +GE+YVC   E FK ++Y +     WSV           N     AS  
Sbjct: 232 GRRVSDIEDLQDGETYVCAGFEGFKVIKYGRTELEPWSVGKSGRLGPLQENEAAPDASYG 411

Query: 163 V------------------SSLATAKGGPSEVRENKDF------------------IRPK 186
                              S+ A   G     R    F                  I+PK
Sbjct: 412 SYKYRGYATNAFHPGRYYRSNAAQGNGVQPTRRWPGTFGNQRNTGGLLTAPGEAVPIKPK 591

Query: 187 LVTIIRSGVKPRKAVRILLNKKTAHSFEQVLTDITDAI--KLDSGVVKRLYTLDGKQVMC 244
           ++TIIR+G +PR  ++ILLN+++  S+EQ+++DI++A   K  S  ++RLYT+ G+++  
Sbjct: 592 VITIIRNGQRPRNNIKILLNRRSIQSYEQLMSDISEAFGPKWKSNRIQRLYTMRGREIKG 771

Query: 245 LQDFFGDDDIFIACGPEKFRYQD 267
           + DFF DDD F+A G E+    D
Sbjct: 772 VADFFRDDDCFVALGNERLSDND 840

 Score = 31.2 bits (69), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 21/89 (23%), Positives = 43/89 (48%), Gaps = 4/89 (4%)
 Frame = +1

Query: 180 KDFIRPKLVTIIRSGVKPRKAVRILLNKKTAHSFEQVLTDIT----DAIKLDSGVVKRLY 235
           +D  RP+ V    +G +  K  ++ +     ++F  +L D+T     +I L  GV +   
Sbjct: 43  RDLRRPRKVRFFVNGDRFFKGKKLHITPHRYYNFTDLLNDLTGKLPSSINLPYGVRQIFT 222

Query: 236 TLDGKQVMCLQDFFGDDDIFIACGPEKFR 264
            + G++V  ++D   D + ++  G E F+
Sbjct: 223 PVGGRRVSDIED-LQDGETYVCAGFEGFK 306
>01392
          Length = 1806

 Score =  133 bits (334), Expect = 3e-31,   Method: Compositional matrix adjust.
 Identities = 77/190 (40%), Positives = 113/190 (59%), Gaps = 26/190 (13%)
 Frame = -1

Query: 500  TERDASGMLYNLASAIKYLHSLNIVHRDIKPENLLVYEHQDGSKSLKLGDFGLATIV--- 556
             ER+AS ++ ++A A+ +LHS  I HRD+KPEN+L  EH D    +K+ DF LA+ +   
Sbjct: 1797 CEREASLVVRHIARALDFLHSKGIAHRDLKPENILC-EHLDDVVPVKICDFDLASGISCD 1621

Query: 557  -DGP----LYTVCGTPTYVAPEII-AETG----YGLKVDIWAAGVITYILLCGFPPFRG- 605
             DG     L T  G+  Y+APE++ A  G    Y  + D+W+ G+I YI+LCG+PPF G 
Sbjct: 1620 GDGTKTPELLTPVGSAEYMAPEVVDAWVGDSFSYDKRCDLWSLGIILYIMLCGYPPFYGQ 1441

Query: 606  SGDD------------QEVLFDQILMGQVDFPSPYWDNVSDSAKELINMMLLVNVDQRFS 653
             G+D            Q++LF+ I  G   FPS  W ++S SAK+LI  +L+    +R+S
Sbjct: 1440 CGEDCGWNRGEACHDCQDMLFNSIQDGHYKFPSQEWTSISSSAKDLIRHLLVREPRKRYS 1261

Query: 654  AVQVLEHPWV 663
            A  VL+HPW+
Sbjct: 1260 AADVLKHPWI 1231
>12721
          Length = 821

 Score =  110 bits (274), Expect = 2e-24,   Method: Compositional matrix adjust.
 Identities = 81/251 (32%), Positives = 134/251 (53%), Gaps = 8/251 (3%)
 Frame = +1

Query: 412 IGDGNFAVVKECIERS-TAREYALKIIKKSKCRGKEHMIQNEVSILRRVKHPNIVLLIEE 470
           IG+G+  +V  CI  S   R+ A+K +   K + +E ++ NEV ++R   HPNIV +   
Sbjct: 112 IGEGSTGIV--CIATSRDGRQMAVKKMDLRKQQRRE-LLFNEVVVMRDYHHPNIVEMYNS 282

Query: 471 MDVPTELYLVMELVKGGDLFDAITSTSKYTERDASGMLYNLASAIKYLHSLNIVHRDIKP 530
             V  EL++VME ++GG L D +T+ ++  E   + +      A+ +LH+  ++HRDIK 
Sbjct: 283 YLVNDELWVVMEFMEGGALTDIVTN-NRMDEVQIATVCRACLKALAFLHANGVIHRDIKS 459

Query: 531 ENLLVYEHQDGSKSLKLGDFGLATIVDGPLY---TVCGTPTYVAPEIIAETGYGLKVDIW 587
           +++L+    DG   +KL DFG    V   L    ++ GTP ++APE+I+   YG +VDIW
Sbjct: 460 DSILL--SHDGK--VKLXDFGFCAQVTQDLQKRKSLVGTPYWMAPEVISRLPYGPEVDIW 627

Query: 588 AAGVITYILLCGFPPFRGSGDDQEVLFDQILMGQV-DFPSPYWDN---VSDSAKELINMM 643
           + G++   ++   PPF      Q        M ++ D P P   N   +S   +  I+ M
Sbjct: 628 SLGIMVMEMIDAEPPFFNEPPLQA-------MRRIRDMPPPKLRNTHKISPRLQGFIDRM 786

Query: 644 LLVNVDQRFSA 654
           L+ +  QR +A
Sbjct: 787 LVRDPHQRATA 819
>13592
          Length = 980

 Score =  103 bits (256), Expect = 3e-22,   Method: Compositional matrix adjust.
 Identities = 82/259 (31%), Positives = 124/259 (47%), Gaps = 11/259 (4%)
 Frame = +2

Query: 412 IGDGNFAVVKECIERSTAREYALK--IIKKSKCRGKEHMIQNEVSILRRVKHPNIVLLIE 469
           IG G F  V   +  +T    A+K   I+  + R  ++ +  E+ IL  +KH N+V    
Sbjct: 8   IGQGRFGKVYTAVNNNTGELMAMKEIAIQPGETRALKN-VAEELKILEGIKHKNLVRYYG 184

Query: 470 EMDVPTELYLVMELVKGGDLFDAITSTSKYTERDASGMLYNLASAIKYLHSLNIVHRDIK 529
                 EL + MEL   G L   +  T    E  +      L S +  LH   IVHRDIK
Sbjct: 185 IEVHREELLIFMELCSEGTLESLVELTGGLPEALSRRFTAQLLSGVAELHKHGIVHRDIK 364

Query: 530 PENLLVYEHQDGSKSLKLGDFGLA------TIVDGPLYTVCGTPTYVAPEIIAET---GY 580
             N+ +    DGS SLKLGDFG A      T V G L    GT  Y+APE+  +T   G+
Sbjct: 365 TANIFLV---DGSNSLKLGDFGSAVKIQAHTTVPGELQGYVGTQAYMAPEVFTKTNSDGH 535

Query: 581 GLKVDIWAAGVITYILLCGFPPFRGSGDDQEVLFDQILMGQVDFPSPYWDNVSDSAKELI 640
           G   DIW+ G +   +  G  P+     + +++F ++ MG+    +P  +++S    + I
Sbjct: 536 GRLADIWSVGCVVVEMASGKRPWAQFDSNFQIMF-KVGMGEKP-QAP--ESLSQEGHDFI 703

Query: 641 NMMLLVNVDQRFSAVQVLE 659
           +  L  +  QR SA+++LE
Sbjct: 704 DHCLQHDPKQRLSAIELLE 760
>21079
          Length = 878

 Score =  103 bits (256), Expect = 4e-22,   Method: Compositional matrix adjust.
 Identities = 55/147 (37%), Positives = 81/147 (55%), Gaps = 3/147 (2%)
 Frame = +1

Query: 461 HPNIVLLIEEMDVPTELYLVMELVKGGDLFD-AITSTSKYTERDASGMLYNLASAIKYLH 519
           HP +++L +  + P  + LVME V  G+LF+  I      TERD    +  + S + Y+H
Sbjct: 1   HPKLLMLWDAFEAPRTMVLVMEFVGAGELFERVIRDDFVLTERDCVHFVRQICSGVGYMH 180

Query: 520 SLNIVHRDIKPENLLVYEHQDGSKSLKLGDFGLATIVD--GPLYTVCGTPTYVAPEIIAE 577
           + +I+H D+KPEN+L     D S  +K+ DFGLA        L  + GTP ++APE++  
Sbjct: 181 TQSILHLDLKPENVLCV--SDNSNQIKIIDFGLARFYKPGDSLQVLFGTPEFIAPEVVNY 354

Query: 578 TGYGLKVDIWAAGVITYILLCGFPPFR 604
                  D+W+ GVI YILL G  P R
Sbjct: 355 DEINFTTDMWSIGVICYILLSGLSPSR 435
>14420
          Length = 528

 Score =  102 bits (255), Expect = 4e-22,   Method: Compositional matrix adjust.
 Identities = 58/162 (35%), Positives = 93/162 (57%), Gaps = 3/162 (1%)
 Frame = +2

Query: 445 KEHMIQNEVSILRRVKHPNIVLLIEEMDVPTELYLVMELVKGGDLFDAITSTSKYTERDA 504
           K+ +I NE+ ++R  ++PNIV  ++   V  EL++VME + GG L D +T T    E   
Sbjct: 29  KKELIINEILVMRENQNPNIVNYLDSYLVGEELWVVMEFLAGGSLTDVVTETC-MDEGQI 205

Query: 505 SGMLYNLASAIKYLHSLNIVHRDIKPENLLVYEHQDGSKSLKLGDFGLATIV---DGPLY 561
           + +      A+++LH   ++HRDIK +N+L+    DG  S+KL DFG    +        
Sbjct: 206 AAVCRECLQALEFLHENQVIHRDIKSDNILL--GMDG--SVKLTDFGFCAQLSPEQSKRS 373

Query: 562 TVCGTPTYVAPEIIAETGYGLKVDIWAAGVITYILLCGFPPF 603
           T+ GTP ++APE++    YG  VDIW+ GV+   ++ G PP+
Sbjct: 374 TMVGTPYWMAPEVVTRKQYGPTVDIWSLGVMCIEMIEGEPPY 499
>09606
          Length = 1300

 Score =  100 bits (250), Expect = 2e-21,   Method: Compositional matrix adjust.
 Identities = 82/319 (25%), Positives = 139/319 (43%), Gaps = 31/319 (9%)
 Frame = -3

Query: 401  TITERYKVGRTIGDGNFAVVKECIERSTAREYALKIIKKSKCRGKEHMIQNEVSILRRVK 460
            T  E + +   +G G  +++ +   + T    A+  I+K  C+  E  + N V +   + 
Sbjct: 1124 TRMENFVLYEELGKGEHSIIYKGRRKGTINFVAIHCIEK--CKRPE--VTNTVRMTHDIS 957

Query: 461  HPNIVLLIEEMDVPTELYLVMELVKGGDLFDAITSTSKYTERDASGMLYNLASAIKYLHS 520
            HPN+V   E  +    L+LV+EL  GG L D +       E        +L + + Y+HS
Sbjct: 956  HPNVVQFHEWYETSNHLWLVVELCTGGSLADILAQDHHLPETSIRDFGIHLVTGLHYIHS 777

Query: 521  LNIVHRDIKPENLLVYEHQDGSKSLKLGDFGLATIVDGPLYTV----------------- 563
            L I+  D++P  +L+    D S  LK  DFGL+ +    L  +                 
Sbjct: 776  LGILFHDLRPSKVLL----DTSGVLKFADFGLSKVEGENLEELFFKFAEAGDQWNIQSAE 609

Query: 564  --------CGTPTYVAPEIIAETGYGLKVDIWAAGVITYILLCGFPPFRGSGDDQEVLFD 615
                     G+PTY+APE+       +  D+WA G + Y +  G PPF G   D  +  D
Sbjct: 608  EMMKQVPTSGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFSGHPPFLGETYD--ITKD 435

Query: 616  QILMGQVDFPSPYWDNVSDSAK---ELINM---MLLVNVDQRFSAVQVLEHPWVNDDGLP 669
            ++L    +FP P       SAK   E +N+   +L  +  +R S   +++H +    GL 
Sbjct: 434  KVL--NKEFPLPKVKGSRLSAKPSPEFLNLLESLLQKDSTRRLSWASLVKHAFWQ-GGLS 264

Query: 670  ENEHQLSVAGKIKKHFNTG 688
                + +++ +I  H + G
Sbjct: 263  SLVKEFTMSEEIGGHCHPG 207
>30755
          Length = 1137

 Score =  100 bits (248), Expect = 3e-21,   Method: Compositional matrix adjust.
 Identities = 60/149 (40%), Positives = 83/149 (55%), Gaps = 3/149 (2%)
 Frame = +2

Query: 511 LASAIKYLHSLNIVHRDIKPENLLVYEHQDGSKSLKLGDFGLAT--IVDG-PLYTVCGTP 567
           + SA+ YLHS  I++RD+K ENLL+    D    +K+ DFGL    I  G    T CGTP
Sbjct: 59  IISALGYLHSQGIIYRDLKLENLLL----DKDGHIKVADFGLCKEDITYGRTTKTFCGTP 226

Query: 568 TYVAPEIIAETGYGLKVDIWAAGVITYILLCGFPPFRGSGDDQEVLFDQILMGQVDFPSP 627
            Y+APE++ +  YG  VD W  GV+ Y ++CG  PF     D +VLF  IL+  V FP  
Sbjct: 227 EYLAPEVLDDNDYGRAVDWWGTGVVMYEMICGRLPFYNR--DHDVLFTLILVEDVKFPR- 397

Query: 628 YWDNVSDSAKELINMMLLVNVDQRFSAVQ 656
              N++D AK L++ +L  +   R    Q
Sbjct: 398 ---NITDEAKSLLSGLLAKDPRNRLGGGQ 475
>01707
          Length = 757

 Score = 99.4 bits (246), Expect = 4e-21,   Method: Compositional matrix adjust.
 Identities = 74/219 (33%), Positives = 111/219 (50%), Gaps = 14/219 (6%)
 Frame = +1

Query: 404 ERY-KVGRTIGDGNFAVVKECIERSTAREYALK---------IIKKSKCRGKEHMIQNEV 453
           E+Y K+G+ IG+G++ VV +C  + T++  A+K         +IKK   R        E+
Sbjct: 64  EKYEKIGK-IGEGSYGVVFKCRNKETSQLVAIKKFVESEDDPLIKKIAMR--------EI 216

Query: 454 SILRRVKHPNIVLLIEEMDVPTELYLVMELVKGGDLFDAITSTSKYTERDASGMLYNLAS 513
            +L+++KHPN+V LIE       L+LV + V    L +         E     ++Y    
Sbjct: 217 RMLKQLKHPNLVRLIEVFRRKKRLHLVFDYVDHTLLNELDRYPRGLPEPMVKRIIYQTLL 396

Query: 514 AIKYLHSLNIVHRDIKPENLLVYEHQDGSKSLKLGDFGLATIVDGP--LYT-VCGTPTYV 570
           A+ + H  N +HRD+KPEN+L+         +KL DFG A I+ GP   YT    T  Y 
Sbjct: 397 AVNFCHQYNTIHRDVKPENILITR----QGQVKLCDFGFARILTGPGDEYTDYVATRWYR 564

Query: 571 APE-IIAETGYGLKVDIWAAGVITYILLCGFPPFRGSGD 608
           APE ++ +T YG  VD+WA G +   LL G   + G  D
Sbjct: 565 APELLVGDTQYGPPVDVWAIGCVFAELLTGQALWPGRSD 681
>03240
          Length = 1683

 Score = 99.4 bits (246), Expect = 5e-21,   Method: Compositional matrix adjust.
 Identities = 84/295 (28%), Positives = 126/295 (42%), Gaps = 52/295 (17%)
 Frame = -3

Query: 410  RTIGDGNFAVVKECIERSTAREYALKIIKKSKC--RGKEHMIQNEVSILRRVKHPNIVLL 467
            +T+G G F  V  C +  T   YA+K ++KS    R +   ++ E  IL    +  +V L
Sbjct: 1273 KTLGVGAFGEVSLCRKNDTGMLYAMKTLRKSDVLKRNQVAHVKAERDILAEADNEWVVKL 1094

Query: 468  IEEMDVPTELYLVMELVKGGDLFDAITSTSKYTERDASGMLYNLASAIKYLHSLNIVHRD 527
                     LY VM+ V GGDL   +       E  A   +  L  AI+ +H +  +HRD
Sbjct: 1093 YYSFQDHNYLYFVMDYVPGGDLMGLLIRMEILDEPLARFYVAELVQAIESVHRMGFIHRD 914

Query: 528  IKPENLLVYEHQDGSKSLKLGDFGLATIV-----------DG------------------ 558
            IKP+N+L+    D +  +KL DFGL T             DG                  
Sbjct: 913  IKPDNILI----DRNGHIKLTDFGLCTGFRWTHNSKYYQRDGTHARQDSMEVKCQLDEQC 746

Query: 559  ------PL------------YTVCGTPTYVAPEIIAET-GYGLKVDIWAAGVITYILLCG 599
                  PL            +++ GTP Y+APE+++   GY    D W+ GVI + +L G
Sbjct: 745  QCEILKPLERRRKREQRCLAHSLVGTPNYIAPEVLSRLGGYTSVCDWWSVGVILFEMLVG 566

Query: 600  FPPFRGS--GDDQEVLFDQILMGQVDFPSPYWDNVSDSAKELINMMLLVNVDQRF 652
             PPF  +   + Q  + +   M ++    P   N+S  AK+LI + L    D R 
Sbjct: 565  HPPFYANTPAETQYKVINWKDMLKI----PRESNLSQPAKDLI-LRLCCGSDDRL 416
>17975
          Length = 449

 Score = 97.8 bits (242), Expect = 2e-20,   Method: Composition-based stats.
 Identities = 57/142 (40%), Positives = 84/142 (59%), Gaps = 3/142 (2%)
 Frame = +3

Query: 416 NFAVVKECIERSTAREYALKIIKKSKCR--GKEHMIQNEVSILRRVKHPNIVLLIEEMDV 473
           +FAVVK      T  + A+K+I K+K     + H+ Q EV  ++ V+HPN+V L E +D 
Sbjct: 3   HFAVVKLARHVFTGEKVAVKVIDKTKLDEVSRSHLFQ-EVRCMKLVQHPNVVRLYEVIDT 179

Query: 474 PTELYLVMELVKGGDLFDAITSTS-KYTERDASGMLYNLASAIKYLHSLNIVHRDIKPEN 532
            T+LYL++EL  GGD++D I   S    E+ A      +  AI Y H L++VHRD+KPEN
Sbjct: 180 QTKLYLILELGDGGDMYDYIMRHSGGLEEKLAKRYFRQIVEAISYCHKLHVVHRDLKPEN 359

Query: 533 LLVYEHQDGSKSLKLGDFGLAT 554
           ++ +E       +KL DFG +T
Sbjct: 360 VVFFEK---PGLVKLTDFGFST 416
>14126
          Length = 1265

 Score = 97.1 bits (240), Expect = 2e-20,   Method: Compositional matrix adjust.
 Identities = 97/324 (29%), Positives = 152/324 (46%), Gaps = 35/324 (10%)
 Frame = +3

Query: 378 GRRHSLQRGWRREESEEGFQIPATITERYKVGRTIGDGNFAVVKECIERSTAREY-ALKI 436
           G+  S  +  RR +S E         ++Y+    IG+G +  V +  +     E+ A+K 
Sbjct: 138 GQSESAAKMSRRRDSTE---------QKYEEVAVIGNGAYGTVYKARDLRNQGEFVAMKR 290

Query: 437 IKKSKCR-GKEHMIQNEVSILRRVK---HPNIVLLIEE-----MDVPTELYLVMELVKGG 487
           I+ +    G   M   E+S+L++++   HPN+V L++       D    L LV E ++  
Sbjct: 291 IRLNNTEEGMPMMAIREISMLKQLEQYEHPNVVRLLDVSHNTITDREIRLNLVFEYIEH- 467

Query: 488 DL--FDAITSTSKYTERDASGMLYNLASAIKYLHSLNIVHRDIKPENLLVYEHQDGSKSL 545
           DL  + A   +          ++  L + + +LHS  IVHRD+KP+NLL+   +DG   L
Sbjct: 468 DLATYLAKCPSPGLGPDRIKDLMLQLLNGVDFLHSNRIVHRDLKPQNLLI--SKDG--RL 635

Query: 546 KLGDFGLATI--VDGPLYTVCGTPTYVAPEIIAETGYGLKVDIWAAGVITYILLCGFPPF 603
           KL DFGLA I      L TV  T  Y +PE++ +  YG  VDIW+ G I   L      F
Sbjct: 636 KLADFGLARIYSFHMALTTVVVTLWYRSPEVLMQAEYGTSVDIWSCGCIFAELFTRRALF 815

Query: 604 RGSG--DDQEVLFDQI-LMGQVDFPS---------------PYWDNVSD---SAKELINM 642
           +GS   D  + +F+ I L    D+P                P    V +    AK+L+  
Sbjct: 816 KGSSEFDQLKKIFEVIGLPPAGDWPEGVSVHRNSFRPTPPVPLQTLVPEMDPQAKDLMEK 995

Query: 643 MLLVNVDQRFSAVQVLEHPWVNDD 666
           ML+    +R S+ + L HP++ DD
Sbjct: 996 MLVFKSGRRISSRESLLHPYLRDD 1067
>01060
          Length = 1800

 Score = 95.9 bits (237), Expect = 5e-20,   Method: Compositional matrix adjust.
 Identities = 88/320 (27%), Positives = 146/320 (45%), Gaps = 44/320 (13%)
 Frame = +1

Query: 412 IGDGNFAVVKECIERSTAREYALKIIKKSKCRGKEHMIQN----EVSILRRVKHPNIVLL 467
           IG+G + VV +C  R+T R+ A+K   K + RG E  + +    E+++LR ++H NIV L
Sbjct: 97  IGEGTYGVVYKCRHRATGRKLAMK---KIRLRGSEDGVPSSAIREIAMLRELRHTNIVCL 267

Query: 468 IEEMDVPTELYLVMELVKGGDLFDAITSTSKYTE------RDASGMLYNLASAIKYLHSL 521
            + +     L+LV E +      D      K+ E      R     ++ + + I + H  
Sbjct: 268 EDVIMEDERLFLVFEFLS----MDLKMYIDKFPEGVVLDRRLVKSYVFQIVTGIXFCHQR 435

Query: 522 NIVHRDIKPENLLVYEHQDGSKSLKLGDFGLATIVDGPL--YT-VCGTPTYVAPEII-AE 577
            IVHRD+KP+NLL+    + + ++K+ DFG+A     P+  YT    T  Y APEI+   
Sbjct: 436 RIVHRDLKPQNLLI----NHTGAIKIADFGMARTFALPVRAYTHEVVTLWYRAPEILMGA 603

Query: 578 TGYGLKVDIWAAGVITYILLCGFPPFRGSGDDQEVLFDQILMG---QVDFPS-------- 626
           + Y   VD+W+ G I   +L   P F+G  +  ++     ++G   +  +P         
Sbjct: 604 SKYSTPVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIFRIIGTPTEQTWPEFHKLPAFN 783

Query: 627 ---PYWD---------NVSDSAKELINMMLLVNVDQRFSAVQVLEHPW-VNDD------G 667
              P W          ++     +LI   L  +  QR S  ++L+H + +N D       
Sbjct: 784 GMFPLWKEGKLSETLTDLDSLGLDLIERTLKCDPAQRISCKKMLQHAYFLNVDTSVKPVD 963

Query: 668 LPENEHQLSVAGKIKKHFNT 687
           +P  EH  S   K K+   T
Sbjct: 964 VPSPEHS*STRLKYKETLRT 1023
>00300
          Length = 2318

 Score = 91.7 bits (226), Expect = 1e-18,   Method: Compositional matrix adjust.
 Identities = 69/269 (25%), Positives = 126/269 (46%), Gaps = 11/269 (4%)
 Frame = -1

Query: 405  RYKVGRTIGDGNFAVVKECIERSTAREYALKIIK-KSKCRGKEHMIQNEVSILRRVKHPN 463
            R++ G  IG+G F  V   +  ST    ALK +K +     +   + +E+ I   ++H N
Sbjct: 1655 RWQRGNKIGEGQFGKVYTAVNMSTGELMALKEMKFQPNDLQQLREMCDEIKIFEGIQHEN 1476

Query: 464  IVLLIEEMDVPTELYLVMELVKGGDLFDAI-TSTSKYTERDASGMLYNLASAIKYLHSLN 522
            +V          E+ + ME    G + +A      +Y  R  +     +  A+ +LH  +
Sbjct: 1475 LVKYYGVEVHKDEMLMFMEYCDTGTIEEAAKMGLPEYLIRRYT---REIVLAVNHLHENS 1305

Query: 523  IVHRDIKPENLLVYEHQDGSKSLKLGDFGLA------TIVDGPLYTVCGTPTYVAPEIIA 576
            IVHRDIK  N+ +      +  +KLGDFG +      T + G  + + GT  Y+APE+  
Sbjct: 1304 IVHRDIKGANIFL----TSNGHVKLGDFGCSVKLKSHTTMPGEFHNLVGTTAYMAPEVFT 1137

Query: 577  ET---GYGLKVDIWAAGVITYILLCGFPPFRGSGDDQEVLFDQILMGQVDFPSPYWDNVS 633
            +    GYG   DIW+ G +   +  G  P+    ++ ++++   +  +   P    D++S
Sbjct: 1136 QNDQGGYGRAADIWSLGCVVIEMATGKRPWHDLDNNYQIMYKVGIGHKPAVP----DSLS 969

Query: 634  DSAKELINMMLLVNVDQRFSAVQVLEHPW 662
               K  +++++  +  QR  A Q+L+H +
Sbjct: 968  VEGKHFLDLIMCHDPAQRALASQLLDHTF 882
>06405
          Length = 1965

 Score = 89.4 bits (220), Expect = 5e-18,   Method: Compositional matrix adjust.
 Identities = 62/217 (28%), Positives = 109/217 (50%), Gaps = 15/217 (6%)
 Frame = +1

Query: 404 ERYKVGRT-------IGDGNFAVVKECIERSTAREYALKIIKKSKCRGKEHMIQNEVSIL 456
           +R+++ RT       +G G +  V E + +   +  A+K +K+      + +   E +I+
Sbjct: 238 DRWEIERTEIAMKHRLGGGQYGDVYEAMWKRYNKIVAVKTLKEDTMALNDFL--EEAAIM 411

Query: 457 RRVKHPNIVLLIEEMDVPTELYLVMELVKGGDLFDAITSTSKYTERDASGMLY---NLAS 513
           + +KHPN+V L+         Y+V E +  G+L D + S+++  E   + ++Y    +AS
Sbjct: 412 KEMKHPNLVQLLGVCTREPPFYIVTEFMPHGNLLDYLRSSTR-EENGPTALMYMATQIAS 588

Query: 514 AIKYLHSLNIVHRDIKPENLLVYEHQDGSKSLKLGDFGLATIVDGPLYTV---CGTPT-Y 569
            + YL + N +HRD+   N LV +    S  +K+ DFGLA ++    YT       P  +
Sbjct: 589 GMAYLETKNFIHRDLAARNCLVAD----SNMVKVADFGLARLMKDDTYTAHIGAKFPIKW 756

Query: 570 VAPEIIAETGYGLKVDIWAAGVITYILLC-GFPPFRG 605
            APE +A   +  + DIWA GV+ + L   G  P+ G
Sbjct: 757 TAPEGLAFNRFSTRSDIWAFGVLLWELATYGMSPYPG 867
>18921
          Length = 697

 Score = 88.6 bits (218), Expect = 9e-18,   Method: Compositional matrix adjust.
 Identities = 61/195 (31%), Positives = 97/195 (49%), Gaps = 4/195 (2%)
 Frame = +2

Query: 412 IGDGNFAVVKECIERSTAREYALKIIKKSKCRGKEHMIQNEVSILRRVKHPNIVLLIEEM 471
           +G+G++  V + + + T +  A   IK+         I  E+SI+++     IV      
Sbjct: 53  LGEGSYGSVFKSLHKETGQVLA---IKQVPVDTDLQEIIKEISIMQQCDSKYIVKYYGSY 223

Query: 472 DVPTELYLVMELVKGGDLFDAITSTSK-YTERDASGMLYNLASAIKYLHSLNIVHRDIKP 530
              T+L++VME    G + D +   +K   ER+ + +LY     + YLHS   +HRDIK 
Sbjct: 224 FKNTDLWIVMEYCGAGSVSDIMRLRNKTLVEREIATILYYTLKGLXYLHSRRKIHRDIKA 403

Query: 531 ENLLVYEHQDGSKSLKLGDFGLATIVDGPLY---TVCGTPTYVAPEIIAETGYGLKVDIW 587
            N+L+    +     KL DFG+A  +   +    TV GTP ++APE+I E GY    DIW
Sbjct: 404 GNILL----NNEGHAKLADFGVAGQLTDTMAKRNTVIGTPYWMAPEVIQEIGYDCVADIW 571

Query: 588 AAGVITYILLCGFPP 602
           + G+    +  G PP
Sbjct: 572 SLGITALEMAEGKPP 616
>02841
          Length = 1442

 Score = 88.6 bits (218), Expect = 9e-18,   Method: Compositional matrix adjust.
 Identities = 59/199 (29%), Positives = 95/199 (47%), Gaps = 52/199 (26%)
 Frame = +3

Query: 121 DQLVEGESYVCGSIEPFKKLEYTKNVNPNWSVNV---------KTTSAS----------- 160
           + L +G++YVC   E FK ++Y +     WSV            T+ AS           
Sbjct: 3   EDLQDGQTYVCAGFEGFKIIKYGRTELEPWSVGKPVRPNQPEDATSEASYGSYKYRGYAS 182

Query: 161 ---------RAVSSLATAK---------------------GGPSEVRENKDFIRPKLVTI 190
                    RA ++   A                      GGP+E       ++P+++TI
Sbjct: 183 NAFHPGRYYRATANHGLAANTNRKWPGTFGNTQRSPAGLLGGPTEAVP----LKPRVITI 350

Query: 191 IRSGVKPRKAVRILLNKKTAHSFEQVLTDITDAI--KLDSGVVKRLYTLDGKQVMCLQDF 248
           +R+G +PR  V++LLN+++  SFEQ++ DI++A   K  +  V++LYT  GK+V  + DF
Sbjct: 351 VRNGHRPRTNVKLLLNRRSIQSFEQLMADISEAFGPKWKNNRVQKLYTTHGKEVNSVSDF 530

Query: 249 FGDDDIFIACGPEKFRYQD 267
           F +DD FIA G E+   +D
Sbjct: 531 FREDDCFIAMGNERLNDRD 587
>18484
          Length = 635

 Score = 86.7 bits (213), Expect = 3e-17,   Method: Compositional matrix adjust.
 Identities = 55/170 (32%), Positives = 83/170 (48%), Gaps = 3/170 (1%)
 Frame = +1

Query: 488 DLFDAITSTSKYTERDASGMLYNLASAIKYLHSLNIVHRDIKPENLLVYEHQDGSKSLKL 547
           DL   I    K+ E  A+     +A  + +LH   I++RD+K +N+++    D    +K+
Sbjct: 1   DLMYRIQQEGKFKEPVAAFYAAEIAVGLFFLHDQGIIYRDLKLDNVML----DSEGHIKI 168

Query: 548 GDFGLA---TIVDGPLYTVCGTPTYVAPEIIAETGYGLKVDIWAAGVITYILLCGFPPFR 604
            DFG+       D    T CGTP Y+APEI+    Y   VD WA GV+ + +L G PPF 
Sbjct: 169 ADFGMCKEGMTGDATTRTFCGTPDYIAPEIVLYQPYSKSVDWWAYGVLLFEMLAGQPPF- 345

Query: 605 GSGDDQEVLFDQILMGQVDFPSPYWDNVSDSAKELINMMLLVNVDQRFSA 654
             G+D++ LF  I    V +P      +S  A  L   +L+ N  +R   
Sbjct: 346 -DGEDEDELFSSITDHNVSYPK----AMSREAVSLCKGLLMKNPTKRLGC 480
>13066
          Length = 551

 Score = 85.1 bits (209), Expect = 9e-17,   Method: Compositional matrix adjust.
 Identities = 55/167 (32%), Positives = 80/167 (47%), Gaps = 9/167 (5%)
 Frame = +3

Query: 433 ALKIIKKSKCRGK--EHMIQNEVSILRRVKHPNIVLLIEEMDVPTELYLVMELVKGGDLF 490
           A KII K K      E     E+ +L ++ HP I+ +   +    + ++ M   + GDL 
Sbjct: 63  ACKIIDKEKAPVDFVEKFFPRELDLLTKLDHPYIIQIHSILQRXPKNFIFMRFAERGDLL 242

Query: 491 DAITSTSKYTERDASGMLYNLASAIKYLHSLNIVHRDIKPENLLVYEHQDGSKSLKLGDF 550
             I       E+ A    Y + +A+ YLHS ++ HRD+K EN+L+  H +    +KL DF
Sbjct: 243 TYIQEVGFVKEKQAKIWFYQMTTALNYLHSYDVAHRDLKCENILLSSHFN----VKLADF 410

Query: 551 GLATIV---DGPLY---TVCGTPTYVAPEIIAETGYGLKV-DIWAAG 590
           G A       G  Y   T CG+  Y APEI+    Y  KV D W+ G
Sbjct: 411 GFACACITESGEKYMSRTYCGSAAYAAPEIVYGAPYAPKVADAWSLG 551
>21433
          Length = 590

 Score = 66.6 bits (161), Expect(2) = 2e-15,   Method: Compositional matrix adjust.
 Identities = 40/99 (40%), Positives = 56/99 (56%), Gaps = 3/99 (3%)
 Frame = +2

Query: 508 LYNLASAIKYLHSLNIVHRDIKPENLLVYEHQDGSKSLKLGDFGLATIVDGP---LYTVC 564
           +Y L+SA++Y H   ++HRDIKPENLL          LK+ DFG +  V  P     T+C
Sbjct: 185 IYQLSSALEYCHYRKVIHRDIKPENLL----LGLKGDLKIADFGWS--VHAPSSRRTTMC 346

Query: 565 GTPTYVAPEIIAETGYGLKVDIWAAGVITYILLCGFPPF 603
           GT  Y+ PE++    +   VD+W+ GV+ Y  L G PP 
Sbjct: 347 GTLDYLPPEMVEGKTHDENVDLWSLGVLCYEFLVGTPPL 463

 Score = 34.7 bits (78), Expect(2) = 2e-15,   Method: Composition-based stats.
 Identities = 14/57 (24%), Positives = 29/57 (50%)
 Frame = +3

Query: 447 HMIQNEVSILRRVKHPNIVLLIEEMDVPTELYLVMELVKGGDLFDAITSTSKYTERD 503
           H ++ E+ I   ++H NI+ +       T +YL++E    G+L+  +    K+ E +
Sbjct: 3   HQLRREIEIQSHLRHDNILRMFGYFHDKTRVYLILEFAPKGELYKELQRCHKFDENE 173
>01718
          Length = 959

 Score = 80.1 bits (196), Expect = 3e-15,   Method: Compositional matrix adjust.
 Identities = 53/192 (27%), Positives = 94/192 (48%), Gaps = 7/192 (3%)
 Frame = +3

Query: 408 VGRTIGDGNFAVVKECIERSTAREYALKIIKKSKCRGKEHMIQNEVSILRRVKHPNIVLL 467
           +   IG G F+ V +   R T +  ALK+   +  R   H +  EV +L R++H NI+  
Sbjct: 159 ICEKIGAGFFSEVFKVTHRITGQVMALKMNTMTSNR---HNMLREVQLLNRLQHANILRF 329

Query: 468 IEEMDVPTELYLVMELVKGGDLFDAITSTSK---YTERDASGMLYNLASAIKYLHSLNIV 524
           +       +L+ + E +  G+L   +    +   +T+R    +   LA  + YLHS   +
Sbjct: 330 MGVCVHEGQLHALTEYIPSGNLEQLLEKKDEELPWTQR--IQLTLGLARGLDYLHSTRFI 503

Query: 525 HRDIKPENLLVYEHQDGSKSLKLGDFGLATIVDGPL----YTVCGTPTYVAPEIIAETGY 580
           HRD+  +N+L+    +      + DFGLAT +  PL        G+P ++APE++    Y
Sbjct: 504 HRDLTSKNILIRREDNHGYHAVIADFGLATKIPDPLDKEKLPTVGSPYWMAPEVLNGHFY 683

Query: 581 GLKVDIWAAGVI 592
             + D+++ G+I
Sbjct: 684 NERADLFSVGII 719
>31885
          Length = 529

 Score = 80.1 bits (196), Expect = 3e-15,   Method: Compositional matrix adjust.
 Identities = 57/158 (36%), Positives = 78/158 (49%), Gaps = 7/158 (4%)
 Frame = -2

Query: 453 VSILRRVKHPNIVLLIEEMDVPTELYLVMELVKGGDLFDAITSTSKYTERDASGMLYNLA 512
           V +L R+ HP +V L        +L++V++L  GGDL   +     + E      L  LA
Sbjct: 519 VDMLTRLDHPFLVNLWYAFQDEEDLFMVVDLFLGGDLRYHMQQEVSFREDCVKFYLCQLA 340

Query: 513 SAIKYLHSLNIVHRDIKPENLLVYEHQDGSKSLKLGDFGLAT-IVDGPLYT-VCGTPTYV 570
             + YL S  IVHRDIKP+N+L+    D      + DF +AT + D  L T   GT  Y+
Sbjct: 339 LVLDYLRSQKIVHRDIKPDNILL----DEQGHCHVTDFNIATQLEDDELATSTSGTRPYM 172

Query: 571 APEIIA-----ETGYGLKVDIWAAGVITYILLCGFPPF 603
           APE+         GYG  VD W+ GV  + LL    PF
Sbjct: 171 APEVYGVAINERRGYGFPVDWWSLGVSLFELLKKRRPF 58
>01966
          Length = 1735

 Score = 68.9 bits (167), Expect(2) = 4e-13,   Method: Compositional matrix adjust.
 Identities = 52/166 (31%), Positives = 84/166 (50%), Gaps = 13/166 (7%)
 Frame = -1

Query: 423  CIERSTAREYALKIIKKSKCRGKEHMIQN----EVSILRRVKHPNIVLLIEEMDVPTELY 478
            C  R+T R+ A+K   K + RG E  + +    E+++LR ++H NIV L + +     L+
Sbjct: 1654 CRHRATGRKLAMK---KIRLRGSEDGVPSSAIREIAMLRELRHTNIVCLEDVIMEDERLF 1484

Query: 479  LVMELVKGGDLFDAITSTSKYTE------RDASGMLYNLASAIKYLHSLNIVHRDIKPEN 532
            LV E +      D      K+ E      R     ++ + + I + H   IVHRD+KP+N
Sbjct: 1483 LVFEFLS----MDLKMYIDKFPEGVVLDRRLVKSYVFQIVTGINFCHQRRIVHRDLKPQN 1316

Query: 533  LLVYEHQDGSKSLKLGDFGLATIVDGPL--YT-VCGTPTYVAPEII 575
            LL+    + + ++K+ DFG+A     P+  YT    T  Y APEI+
Sbjct: 1315 LLI----NHTGAIKIADFGMARTFALPVRAYTHEVVTLWYRAPEIL 1190

 Score = 23.9 bits (50), Expect(2) = 4e-13,   Method: Compositional matrix adjust.
 Identities = 10/34 (29%), Positives = 17/34 (50%)
 Frame = -3

Query: 580  YGLKVDIWAAGVITYILLCGFPPFRGSGDDQEVL 613
            Y   VD+W+ G I   +L   P F+G  +  ++ 
Sbjct: 1175 YSTPVDVWSIGTIFADMLIRTPIFKGDSEIDQLF 1074
>00486
          Length = 797

 Score = 72.0 bits (175), Expect = 7e-13,   Method: Compositional matrix adjust.
 Identities = 40/115 (34%), Positives = 63/115 (54%)
 Frame = -2

Query: 561 YTVCGTPTYVAPEIIAETGYGLKVDIWAAGVITYILLCGFPPFRGSGDDQEVLFDQILMG 620
           +T CGT  Y+APEI+  TG+G  VD W+ G + Y +L G PPF  + ++++   D+IL G
Sbjct: 784 HTFCGTIEYMAPEILTRTGHGKAVDWWSLGALMYDMLTGSPPF--TAENRKKTIDKILKG 611

Query: 621 QVDFPSPYWDNVSDSAKELINMMLLVNVDQRFSAVQVLEHPWVNDDGLPENEHQL 675
           +++ P PY   +++ A+ LI  +L  N  +R             DD  P  +HQ 
Sbjct: 610 KLNLP-PY---LTNEARGLIKKLLRKNPAERLGGGH--------DDSGPIKDHQF 482
>19761
          Length = 473

 Score = 72.0 bits (175), Expect = 8e-13,   Method: Compositional matrix adjust.
 Identities = 52/155 (33%), Positives = 81/155 (52%), Gaps = 6/155 (3%)
 Frame = -3

Query: 496 TSKYTERDASGMLYNLASAIKYLHSLN--IVHRDIKPENLLVYEHQDGSKSLKLGDFGLA 553
           T+   ER     L   ASA+ Y+H+    I+HRD+KP+N+ V E  D    ++LGD GLA
Sbjct: 441 TAGLPERLIVCWLMQTASALNYMHTHTPVILHRDLKPQNIYVTEKGD----VRLGDLGLA 274

Query: 554 TIVDGPL---YTVCGTPTYVAPEIIAETGYGLKVDIWAAGVITYILLCGFPPFRGSGDDQ 610
             + GP     +  GT  Y++PEI+++  Y  K DIW+ G + Y +       +   D+ 
Sbjct: 273 RKLTGPADFATSQVGTIMYLSPEILSQQPYNSKSDIWSLGCVFYDITG-----KKGSDEM 109

Query: 611 EVLFDQI-LMGQVDFPSPYWDNVSDSAKELINMML 644
            V+F  + +MG    P P  D+ S   ++ I+ ML
Sbjct: 108 GVMFLLVQVMGGRKLPLP--DHYSQEFRDTISRML 10
>27405
          Length = 532

 Score = 71.6 bits (174), Expect = 1e-12,   Method: Compositional matrix adjust.
 Identities = 47/167 (28%), Positives = 84/167 (50%), Gaps = 7/167 (4%)
 Frame = -3

Query: 416 NFAVVKECIERSTAREYALKII--KKSKCRGKEHMIQNEVSILRRVK----HPNIVLLIE 469
            F  V  C +  T + YA+K +  K+ K +G E +  NE  +L  V      P IV +  
Sbjct: 530 GFGEVYGCRKADTGKMYAMKCLDKKRIKMKGGETLALNERIMLSLVSTGEGSPFIVCMTY 351

Query: 470 EMDVPTELYLVMELVKGGDLFDAITSTSKYTERDASGMLYNLASAIKYLHSLNIVHRDIK 529
               P +L  +++L+ GGDL   ++    +TE++       +   ++++HS  +V+RD+K
Sbjct: 350 AFQTPEKLCFILDLMNGGDLHYHLSQHGVFTEKEVRFYAAEVMLGLEHMHSRFVVYRDLK 171

Query: 530 PENLLVYEHQDGSKSLKLGDFGLAT-IVDGPLYTVCGTPTYVAPEII 575
           P N+L+    D +  +++ D GLA        +   GT  Y+APE++
Sbjct: 170 PANILL----DENGHVRISDLGLACDFSKKKPHASVGTHGYMAPEVL 42
>11780
          Length = 1713

 Score = 71.6 bits (174), Expect = 1e-12,   Method: Compositional matrix adjust.
 Identities = 55/173 (31%), Positives = 93/173 (53%), Gaps = 2/173 (1%)
 Frame = +3

Query: 407 KVGRTIGDGNFAVVKECIERSTAREYALKIIKKSKCRGKEHMIQNEVSILRRVKHPNIVL 466
           ++G  IG G+F  V + + R   +  A+K +K  K RG++  +Q E S++  ++H N+V 
Sbjct: 606 EIGEAIGKGDFGDVYKGMYR--GQPVAIKQLK-DKDRGEQSFLQ-EASVMTSLRHDNLVR 773

Query: 467 LIEEMDVPTELYLVMELVKGGDLFDAITSTSK--YTERDASGMLYNLASAIKYLHSLNIV 524
           LI  + +   ++LV E +  G+L + + S  +   T++D      +  +A++YL S  +V
Sbjct: 774 LIGVV-LGETIFLVTEFMGKGNLVEYLRSRGRSVITKKDQINFATDTCAAMEYLESKRLV 950

Query: 525 HRDIKPENLLVYEHQDGSKSLKLGDFGLATIVDGPLYTVCGTPTYVAPEIIAE 577
           HRD+   N+LV  H DG    K+ DFGLA   D    +V     + APE + E
Sbjct: 951 HRDLAARNVLV--HDDGKA--KVSDFGLAKFGDFSQTSVKFPIKWTAPEALRE 1097
>26711
          Length = 405

 Score = 70.9 bits (172), Expect = 2e-12,   Method: Composition-based stats.
 Identities = 44/137 (32%), Positives = 69/137 (50%), Gaps = 2/137 (1%)
 Frame = -2

Query: 506 GMLYNLASAIKYLHSLNIVHRDIKPENLLVYEHQDGSKSLKLGDFGLATIVDGPLYTVC- 564
           G++  +   ++++H+  +VH D+KP NLL+    D   S++L DFGLA  +  P  T   
Sbjct: 404 GVVKQVLDILQHVHAQGVVHMDLKPSNLLL--SGDKLDSVQLIDFGLARKLYPPQETFLN 231

Query: 565 -GTPTYVAPEIIAETGYGLKVDIWAAGVITYILLCGFPPFRGSGDDQEVLFDQILMGQVD 623
            GTP + +PE +         D+W  GV+ YILL G  PF+     + +   Q      D
Sbjct: 230 HGTPGFTSPEALDVKPISTASDVWGVGVLAYILLSGQSPFQADSATESLKKTQTCDWSFD 51

Query: 624 FPSPYWDNVSDSAKELI 640
              P + N+S  AK+ I
Sbjct: 50  V-CPSFSNMSQDAKDFI 3
>29581
          Length = 1278

 Score = 67.4 bits (163), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 67/251 (26%), Positives = 108/251 (43%), Gaps = 35/251 (13%)
 Frame = -2

Query: 454  SILRRVKHPNIVLLIE-----EMDVPTELYLVMELVKG--GDLFDAITSTSKYTERDASG 506
            + L  ++H NIV L E      +D    L+LVME  +     L D + +   ++E     
Sbjct: 1199 TFLLNLRHQNIVQLQEVVVGKSLD---SLFLVMEYCEQDLASLLDNMPAP--FSESQVKC 1035

Query: 507  MLYNLASAIKYLHSLNIVHRDIKPENLLVYEHQDGSKSLKLGDFGLATIV---DGPLYTV 563
            ++  L   ++YLH   I+HRD+K  NLL+ +       +K+ DFGLA        P+   
Sbjct: 1034 IVLQLLKGLRYLHEAFIIHRDLKVSNLLMTD----KGCVKIADFGLARNYGKPQKPMTPK 867

Query: 564  CGTPTYVAPEII-AETGYGLKVDIWAAGVITYILLCGFPPFRGSGDDQEVLF-------- 614
              T  Y APE++     +   +D+W+AG I   LL   P   G  D Q++          
Sbjct: 866  VVTLWYRAPELLFGSKTHSTAIDMWSAGCILGELLGHKPLMPGRSDLQQIELIMELLGTP 687

Query: 615  -DQILMGQVDFPS---------PY------WDNVSDSAKELINMMLLVNVDQRFSAVQVL 658
             D I  G    P+         PY      +  +S+S   L+N + + +  +R +A   L
Sbjct: 686  NDTIWPGFSQLPAFEQFTLKKQPYNNLRHTFPWLSESGIRLLNGLFMYHPQKRATAEDCL 507

Query: 659  EHPWVNDDGLP 669
            EH +  +   P
Sbjct: 506  EHSYFKEQPYP 474
>28638
          Length = 1458

 Score = 53.5 bits (127), Expect(2) = 2e-11,   Method: Compositional matrix adjust.
 Identities = 34/119 (28%), Positives = 61/119 (51%), Gaps = 10/119 (8%)
 Frame = -1

Query: 495 STSKYTERDASGMLYNL--------ASAIKYLHS--LNIVHRDIKPENLLVYEHQDGSKS 544
           ST+ Y  +   G+  NL         +A+ +L +  +NI+H D+KPEN+L+   +  +  
Sbjct: 882 STTCYATQTLEGVSLNLTRKFAQQLCTALLFLATPEMNIIHCDLKPENILLCNPKRSA-- 709

Query: 545 LKLGDFGLATIVDGPLYTVCGTPTYVAPEIIAETGYGLKVDIWAAGVITYILLCGFPPF 603
           +K+ DFG +  +   +Y    +  Y +PE++    Y L +D+W+ G I   +  G PP 
Sbjct: 708 IKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGVPYDLAIDMWSLGCILVEMHTGEPPL 532

 Score = 33.9 bits (76), Expect(2) = 2e-11,   Method: Compositional matrix adjust.
 Identities = 35/140 (25%), Positives = 57/140 (40%), Gaps = 12/140 (8%)
 Frame = -3

Query: 370  GPGEGDELGRR------HSLQRGWRREESEEGFQIPATITERYKVGRTIGDGNFAVVKEC 423
            G  +GDE G +      H    G+     +          +RY++   IG G+F  V + 
Sbjct: 1267 GTTQGDESGNKKNKVNIHVFNDGYDDSNHDYIINPGEKWLDRYEIDSLIGKGSFGQVVKA 1088

Query: 424  IERSTAREYALKIIKKSKCRGKEHMIQNEVSILRRVKHPN------IVLLIEEMDVPTEL 477
             +     + A+KIIK  K    +  I  EV +L  +   +      IV L         L
Sbjct: 1087 YDHGDQEQVAIKIIKNKKPFLNQAQI--EVKLLELMNRHDADNXYYIVRLKRHFMFRNHL 914

Query: 478  YLVMELVKGGDLFDAITSTS 497
             LV EL+   +L+D + +T+
Sbjct: 913  CLVFELL-SYNLYDLLRNTN 857
>27546
          Length = 426

 Score = 66.6 bits (161), Expect = 3e-11,   Method: Composition-based stats.
 Identities = 33/102 (32%), Positives = 56/102 (54%)
 Frame = -1

Query: 452 EVSILRRVKHPNIVLLIEEMDVPTELYLVMELVKGGDLFDAITSTSKYTERDASGMLYNL 511
           E+ IL R+ HPNI+ +   +    ++++ M   + GD+   I  T    E       + +
Sbjct: 330 ELEILTRLDHPNIIQIHSILQRGPKIFIFMRYAEKGDMLSHIKKTGPIDEAQTKVWFFQM 151

Query: 512 ASAIKYLHSLNIVHRDIKPENLLVYEHQDGSKSLKLGDFGLA 553
           A A++YLHS +I HRD+K EN+L+ +  +    +K+ DFG A
Sbjct: 150 AKALQYLHSHDIAHRDLKCENILLSKRLN----VKIADFGFA 37
>19094
          Length = 898

 Score = 66.2 bits (160), Expect = 4e-11,   Method: Compositional matrix adjust.
 Identities = 37/95 (38%), Positives = 53/95 (55%), Gaps = 3/95 (3%)
 Frame = +1

Query: 500 TERDASGMLYNLASAIKYLHSLNIVHRDIKPENLLVYEHQDGSKSLKLGDFGLATIVDGP 559
            ER+ + +LY     + YLHS   +HRDIK  N+L+    +     KL DFG+A  +   
Sbjct: 52  VEREIATILYYTLKGL*YLHSRRKIHRDIKAGNILL----NNEGHAKLADFGVAGQLTDT 219

Query: 560 LY---TVCGTPTYVAPEIIAETGYGLKVDIWAAGV 591
           +    TV GTP ++APE+I E GY    DIW+ G+
Sbjct: 220 MAKRNTVIGTPYWMAPEVIQEIGYDCVADIWSLGI 324
>38560
          Length = 479

 Score = 65.9 bits (159), Expect = 5e-11,   Method: Compositional matrix adjust.
 Identities = 39/110 (35%), Positives = 60/110 (54%), Gaps = 1/110 (0%)
 Frame = -3

Query: 556 VDGPLYTVCGTPTYVAPEIIAETGY-GLKVDIWAAGVITYILLCGFPPFRGSGDDQEVLF 614
           +D  L T CG+P Y APE+I+   Y G + DIW+ GV+ Y LLCG+ PF    D++    
Sbjct: 426 MDHHLTTCCGSPAYAAPELISGLEYLGSEADIWSMGVLLYALLCGYLPF---DDEKXSHL 256

Query: 615 DQILMGQVDFPSPYWDNVSDSAKELINMMLLVNVDQRFSAVQVLEHPWVN 664
            Q    + D   P W  +S+   +L+  ML  +   R +  ++L+H W+N
Sbjct: 255 *QKNQKRKD-EVPEW--LSEDTTKLLEGMLQTDPSHRITIRRLLDHHWLN 115
>28157
          Length = 400

 Score = 63.9 bits (154), Expect = 2e-10,   Method: Composition-based stats.
 Identities = 45/124 (36%), Positives = 67/124 (54%), Gaps = 7/124 (5%)
 Frame = +3

Query: 437 IKKSKCRGKEHMIQNEVSILRRVKHPNIVLLIEE-MDVPTELYLVMELVKGGDLFDAITS 495
           +K+ +   ++     E+  L RV HPNIV L     D P  + LVME  +GG L++ +  
Sbjct: 15  VKRIESEQEKKSFMQELKQLSRVSHPNIVCLYGACRDHP--VCLVMEYAEGGSLYNVLHG 188

Query: 496 TS---KYTERDASGMLYNLASAIKYLHSLN---IVHRDIKPENLLVYEHQDGSKSLKLGD 549
           +    +YT   A   L   A  ++YLH +    ++HRD+KP NLL+   Q G+K LK+ D
Sbjct: 189 SGPQPQYTAAHAMNWLLQCALGVEYLHGMKPKALIHRDLKPPNLLLI--QCGTK-LKICD 359

Query: 550 FGLA 553
           FG A
Sbjct: 360 FGTA 371
>13212
          Length = 1067

 Score = 63.9 bits (154), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 53/176 (30%), Positives = 85/176 (48%), Gaps = 12/176 (6%)
 Frame = -1

Query: 500 TERDASGMLYNLASAIKYLHSLNIVHRDIKPENLLVYEHQDGSKSLKLGDFGLA---TIV 556
           TE     + + +  A+ +LH  +++HRDIK  N+L+    DG   +KL DFG++   T  
Sbjct: 986 TEAQICYVCHEMCMALDFLHRHHVIHRDIKAGNVLLT--IDG--EVKLADFGVSAKNTQT 819

Query: 557 DGPLYTVCGTPTYVAPEII-----AETGYGLKVDIWAAGVITYILLCGFPPFRGSGDDQE 611
                T  GTP ++APE++      +T Y  K DIW+ GV T I      P         
Sbjct: 818 QQKRDTFIGTPYWMAPEVVLCETLKDTPYDFKADIWSLGV-TLIEFAQIEPPNKEMHPMR 642

Query: 612 VLFDQILMGQVDFPS----PYWDNVSDSAKELINMMLLVNVDQRFSAVQVLEHPWV 663
           VL   I + + D P+      W  +    K+ I   L+ + + R +A ++LEHP++
Sbjct: 641 VL---IKIHKSDPPTLEKPKKWTKL---FKDFIAKCLVKDPNLRPTAAELLEHPFM 492
>09007
          Length = 1440

 Score = 63.2 bits (152), Expect = 4e-10,   Method: Compositional matrix adjust.
 Identities = 59/235 (25%), Positives = 100/235 (42%), Gaps = 17/235 (7%)
 Frame = -1

Query: 408 VGRTIGDGNFAVVKECI---ERSTAREYALKIIKKSKCRGKEHMIQNEVSILRRVKHPNI 464
           + +++G G+F  V++ I   E     + A+K + K K          E +I++ + H NI
Sbjct: 867 LSKSLGQGHFGTVRQAIWTAESGEKVQVAVKCLSKDKIHKDGQEFLKETAIMQMLDHENI 688

Query: 465 VLLIEE-MDVPTELYLVMELVKGGDLFDAITSTSKYTERDASGML---YNLASAIKYLHS 520
           V +    MD   ++ LV EL     L + +   S   +     +      +   + YL S
Sbjct: 687 VRVYGVVMDNGADIMLVTELAPMRSLLECVKEVSARVDFSVPRLCDFSQQVCDGMSYLES 508

Query: 521 LNIVHRDIKPENLLVYEHQDGSKS-LKLGDFGLA-TIVDGPLY-------TVCGTPTYVA 571
             +VHRD+   N+L++     SKS +K+ D G++  +  G  Y        +     + A
Sbjct: 507 KRLVHRDLAARNILLF-----SKSKVKISDVGVSGALGAGKEYYQSQQTIHLQNAVAWCA 343

Query: 572 PEIIAETGYGLKVDIWAAGVITYILLC-GFPPFRGSGDDQEVLFDQILMGQVDFP 625
           PE      +    D+WA GV+ +     GF P+ G       L  Q +M  VD P
Sbjct: 342 PESFRNLCFSSASDVWAFGVLLWEFFTHGFQPWAG-------LNGQQIMEAVDAP 199
>04591
          Length = 1117

 Score = 62.4 bits (150), Expect = 6e-10,   Method: Compositional matrix adjust.
 Identities = 66/256 (25%), Positives = 110/256 (42%), Gaps = 38/256 (14%)
 Frame = -2

Query: 452  EVSILRRVKHPNIVLLIEEMDV--------PTELYLVMELVKGGDLFDAITSTS-KYTER 502
            E+ IL++++H N+V L E             +  YL+ E     DL   + +   K++  
Sbjct: 1071 EIKILQQLEHENVVQLQEICHTQAGPYNRYKSTFYLIFEYCDY-DLAGLLNNLRVKFSLA 895

Query: 503  DASGMLYNLASAIKYLHSLNIVHRDIKPENLLVYEHQDGSKSLKLGDFGLA--TIVDGPL 560
            D   ++  L + + Y+H+  I+HRDIK  N+L+   +DG   LKL DFGL+   +    L
Sbjct: 894  DKKNLMSQLLNGLFYIHTKQILHRDIKAANILLT--RDG--VLKLADFGLSRPWVKSKRL 727

Query: 561  YTVCGTPTYVAPE-IIAETGYGLKVDIWAAGVITYILLCGFPPFRGSGDDQEV-LFDQI- 617
                 T  Y  PE ++ E  YG ++D+W  G I   +    P  +G  +  ++ L   + 
Sbjct: 726  TNRVVTLWYRPPELLLGEREYGPEIDMWGVGCIMAEMWSRKPLMQGRSEQHQLSLITDLC 547

Query: 618  ---------------LMGQVDFPSPYWDNVSD---------SAKELINMMLLVNVDQRFS 653
                           L G++D P      V +            ELI++ L ++  QR +
Sbjct: 546  GSLNAEVWPGVTKLELYGKLDLPQGKPRKVKERMLDLLKNKEGAELIDIFLRLDPGQRMN 367

Query: 654  AVQVLEHPWVNDDGLP 669
                L H +   D LP
Sbjct: 366  CDNALSHDFFWVDPLP 319
>21808
          Length = 1011

 Score = 62.4 bits (150), Expect = 7e-10,   Method: Compositional matrix adjust.
 Identities = 48/187 (25%), Positives = 91/187 (48%), Gaps = 6/187 (3%)
 Frame = +1

Query: 433 ALKIIKKSKCRGKEHMIQNEVSILRRVKHPNIVLLIEEMDVPTELYLVMELVKGGDLFDA 492
           A+K +K      K+ +   E  I+++++HP ++ L         ++++ EL+K G L + 
Sbjct: 31  AIKTLKSGTMDPKDFL--AEAQIMKKLRHPKLIQLYAVCTQDDPIFIITELMKNGSLLEF 204

Query: 493 ITSTSKYTERDAS-GMLYNLASAIKYLHSLNIVHRDIKPENLLVYEHQDGSKSLKLGDFG 551
           +    +  +  A   +   +A  + YL S N +HRD+   N+LV +    + ++K+ DFG
Sbjct: 205 LQGKGRVLKLPALIDIGAQIACGMAYLESQNYIHRDLAARNILVSD----NNTVKIADFG 372

Query: 552 LATIVDGPLYTV---CGTPT-YVAPEIIAETGYGLKVDIWAAGV-ITYILLCGFPPFRGS 606
           LA ++    Y        P  + APE      + +K D+W+ G+ +T  +  G  P+ G 
Sbjct: 373 LARVIKEDEYEARVGARFPIKWTAPEAANYNRFTIKSDVWSFGILLTETVTYGRVPYPGM 552

Query: 607 GDDQEVL 613
             + EVL
Sbjct: 553 -TNAEVL 570
>01756
          Length = 1858

 Score = 61.2 bits (147), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 61/235 (25%), Positives = 103/235 (43%), Gaps = 17/235 (7%)
 Frame = -3

Query: 405  RYKVGRTIGDGNFAVVKECIERSTAREYALK-IIKKSKCRGKEHMIQNEVSILRRVKHPN 463
            +Y+    IG G F  V +   + T +  A+K ++  ++  G       E+ IL+ + H N
Sbjct: 1739 KYEKLAKIGQGTFGEVFKARCKKTKQVVAMKKVLMDNEKEGFPITALREIKILQLLNHEN 1560

Query: 464  IVLLIEEMDVP--------TELYLVMELVKGGDLFDAITSTSK-YTERDASGMLYNLASA 514
            +V LIE             +  YLV E  +  DL   +++ S  +   +   ++  L + 
Sbjct: 1559 VVDLIEICSTKATSANRYKSMFYLVFEFCEH-DLAGLLSNMSVVFNLPEIKEVMKQLMNG 1383

Query: 515  IKYLHSLNIVHRDIKPENLLVYEHQDGSKSLKLGDFGLATIVDGPL-----YT-VCGTPT 568
            + Y+H   I+HRD+K  N+L+ +       LKL DFGLA      L     YT    T  
Sbjct: 1382 LYYIHRNKILHRDMKAANILITKQ----GVLKLADFGLARAFSVNLRQPNRYTNRVVTLW 1215

Query: 569  YVAPE-IIAETGYGLKVDIWAAGVITYILLCGFPPFRGSGDDQEVLFDQILMGQV 622
            Y  PE ++ +  Y   +D W AG I   +    P  +G+ +  ++     L G +
Sbjct: 1214 YRPPELLLGDRNYSTAIDQWGAGCIMAEMWTRNPIMQGTTEQNQLTLITQLCGSI 1050
>00392
          Length = 668

 Score = 60.8 bits (146), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 42/157 (26%), Positives = 77/157 (49%), Gaps = 8/157 (5%)
 Frame = +3

Query: 443 RGKEHMIQNEVSILRRVKHPNIVLLIEEMDVPTE-----LYLVMELVKGGDLFDAITSTS 497
           + +    + E  +L+ ++HPNIV   +  +         + LV EL+  G L   +    
Sbjct: 54  KAERQRFKEEAEMLKELQHPNIVRFFDYWEEHNHRNRKVIILVTELMTSGTLKTYLKRFK 233

Query: 498 KYTERDASGMLYNLASAIKYLHSLN--IVHRDIKPENLLVYEHQDGSKSLKLGDFGLATI 555
           K   +        +   + +LH+    ++HRD+K +N+ +      + S+K+GD GLAT+
Sbjct: 234 KPNVKILKNWCRQVLKGLYFLHTRTPPVIHRDLKCDNIFI---TGPTGSVKIGDLGLATL 404

Query: 556 VDGPLY-TVCGTPTYVAPEIIAETGYGLKVDIWAAGV 591
            +     +V GTP ++APE+  E  Y   VD++A G+
Sbjct: 405 KNQSFAKSVIGTPEFMAPEMYEE-HYDEAVDVYAFGM 512
>03508
          Length = 1463

 Score = 58.5 bits (140), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 38/117 (32%), Positives = 64/117 (54%), Gaps = 3/117 (2%)
 Frame = +1

Query: 479 LVMELVKGGDLFDAITSTSKYTERDASGMLYNLASAIKYLHSLNIVHRDIKPENLLVYEH 538
           L+ E V   D F  +  T  +T+ D    LY L  A+ + HS+ I+HRD+KP N+++ +H
Sbjct: 811 LIFEHVNNTD-FKQLYQT--FTDYDIRFYLYELMKALDFCHSMGIMHRDVKPHNVMI-DH 978

Query: 539 QDGSKSLKLGDFGLATIVD-GPLYTV-CGTPTYVAPEIIAETG-YGLKVDIWAAGVI 592
           ++  K L+L D+GLA     G  Y V   +  +  PE++ +   Y   +D+W+ G +
Sbjct: 979 EN--KKLRLIDWGLAEFYHPGMEYNVRVASRYFKGPELLLDYQMYDYSLDMWSLGCM 1143
>36002
          Length = 253

 Score = 57.8 bits (138), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 28/62 (45%), Positives = 38/62 (61%)
 Frame = +1

Query: 602 PFRGSGDDQEVLFDQILMGQVDFPSPYWDNVSDSAKELINMMLLVNVDQRFSAVQVLEHP 661
           P     D QE+LF++I  G   FPS  W  +S SAK+LI  +L+    +R+SA  VL+HP
Sbjct: 25  PGEACQDCQELLFNRIQDGNYFFPSMEWSAISSSAKDLIRHLLVREPRKRYSAADVLKHP 204

Query: 662 WV 663
           WV
Sbjct: 205 WV 210
>29590
          Length = 320

 Score = 47.4 bits (111), Expect(2) = 2e-08,   Method: Composition-based stats.
 Identities = 20/59 (33%), Positives = 34/59 (57%), Gaps = 2/59 (3%)
 Frame = +3

Query: 549 DFGLATIVDG--PLYTVCGTPTYVAPEIIAETGYGLKVDIWAAGVITYILLCGFPPFRG 605
           D G A + +    +  + GTP YVAPE++      ++ D+W+ GV++Y++L    PF G
Sbjct: 6   DLGFACLTNTGEDIRDIIGTPDYVAPEVLDYEPLSIQTDMWSLGVLSYVMLTACSPFVG 182

 Score = 30.0 bits (66), Expect(2) = 2e-08,   Method: Composition-based stats.
 Identities = 14/47 (29%), Positives = 26/47 (55%)
 Frame = +2

Query: 607 GDDQEVLFDQILMGQVDFPSPYWDNVSDSAKELINMMLLVNVDQRFS 653
           GD+Q+  F  I   ++DFP   + ++S  AK+ I  +L+ +   R +
Sbjct: 179 GDNQQETFCNISQVKLDFPDDLFSHISPHAKDFIKKLLVKDPRHRMT 319
>18663
          Length = 600

 Score = 57.0 bits (136), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 29/71 (40%), Positives = 38/71 (53%), Gaps = 7/71 (9%)
 Frame = +2

Query: 562 TVCGTPTYVAPEIIAETGYGLKVDIWAAGVITYILLCGFPPFRGSG-------DDQEVLF 614
           T CGTP Y+APEI+    YG  VD WA GV+ Y +L G  PF  +G       + ++ LF
Sbjct: 5   TFCGTPNYIAPEILRGEDYGFSVDWWALGVLLYEMLAGRSPFDIAGASENPDQNTEDYLF 184

Query: 615 DQILMGQVDFP 625
             IL   +  P
Sbjct: 185 QVILEKTIRIP 217
>12786
          Length = 460

 Score = 56.6 bits (135), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 35/116 (30%), Positives = 58/116 (50%), Gaps = 25/116 (21%)
 Frame = -3

Query: 514 AIKYLHSLNIVHRDIKPENLLVYEHQDGSKSLKLGDFGLATIVDGPLYTV-----CGTPT 568
           A+K LH+  ++H D+KP N ++      + +LKL DFG+A  +     +V      GTP+
Sbjct: 374 AVKALHNEGVIHSDLKPANFMLV-----AGNLKLIDFGIANTLQQDKTSVLKDSRVGTPS 210

Query: 569 YVAPEIIA------------ETGY--------GLKVDIWAAGVITYILLCGFPPFR 604
           Y++PE I             E G+        G++ D+W+ G I Y ++ G  PF+
Sbjct: 209 YMSPEAIMAACDDSADDSMEEDGHRTKPKYKVGVRSDVWSLGCILYNMVYGRTPFQ 42
>14116
          Length = 1017

 Score = 56.2 bits (134), Expect = 5e-08,   Method: Compositional matrix adjust.
 Identities = 59/210 (28%), Positives = 92/210 (43%), Gaps = 16/210 (7%)
 Frame = -1

Query: 404 ERYKVGRTIGDGNFAVVKECI----ERSTAREYALKIIKKSKCRGKE-HMIQNEVSILRR 458
           E   +G  IG GNF  VK       E+      A+K +  +  R  E      E  I++ 
Sbjct: 636 EFLTMGEEIGKGNFGCVKRGFLTLPEQKGDILVAVKTLHNNNPREIELQSFLQEALIMKD 457

Query: 459 VKHPNIVLLIEEM----DVPTELYLVMELVKGGDLFDAI-TSTSKYTERDASGMLYNLAS 513
             H N++ LI       D+P    +V+  +K GDL   I     + T +D      ++A 
Sbjct: 456 FHHSNVLTLIGICLNLDDMPL---VVLPFMKHGDLLTYIRDDQHQPTIKDLIMYGVDIAR 286

Query: 514 AIKYLHSLNIVHRDIKPENLLVYEHQDGSKSLKLGDFGLA-TIVDGPLYTV----CGTPT 568
            + YL  L  VHRD+   N ++    D    +K+ DFGLA  I +   Y+        P 
Sbjct: 285 GMDYLAGLKFVHRDLAARNCML----DEDFHVKVADFGLARDIYEKEYYSSENKKAKLPV 118

Query: 569 -YVAPEIIAETGYGLKVDIWAAGVITYILL 597
            ++A E + +  Y  K D+W+ GV+ + LL
Sbjct: 117 KWMALESLEKGNYDSKTDVWSYGVVLWELL 28
>31489
          Length = 329

 Score = 55.1 bits (131), Expect = 1e-07,   Method: Composition-based stats.
 Identities = 34/89 (38%), Positives = 48/89 (53%), Gaps = 7/89 (7%)
 Frame = +3

Query: 453 VSILRRVKHPNIVLLIEEMDVPTELY-------LVMELVKGGDLFDAITSTSKYTERDAS 505
           + IL+  KH NI+  I E+  P + Y       +V +L++  DL   I S    TE    
Sbjct: 3   IKILKHFKHDNIIS-IREILKPKDSYHDFKDIHVVFDLMES-DLHRIIYSDQPLTEEHIR 176

Query: 506 GMLYNLASAIKYLHSLNIVHRDIKPENLL 534
             LY +   +KY+HS N+VHRD+KP NLL
Sbjct: 177 YFLYQILRGLKYIHSANVVHRDLKPSNLL 263
>04852
          Length = 1462

 Score = 54.3 bits (129), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 56/231 (24%), Positives = 98/231 (42%), Gaps = 32/231 (13%)
 Frame = +1

Query: 429 AREYALKIIKKSKCRGKEHMIQNEVSILRRVK----HPNIVLLIEEMDVPTELYLVMELV 484
           A   A+K+++      +E     E+ +++ VK    H NIV  +        L++++E  
Sbjct: 19  ASTVAVKMLRDIVTAVEEQDFVQELQVMKAVKKMGSHINIVNFLGCCTQGGPLWVIVEFA 198

Query: 485 KGGDLFDAITST----------------SKYTERDASGML---------YNLASAIKYLH 519
           K G+L D + S                   YT+     ++         + +A  +++L 
Sbjct: 199 KNGNLRDFLESCRDGINGYGKFVSPQDPGWYTKTPGGHVIRRKNLLSYAFQIARGMEFLA 378

Query: 520 SLNIVHRDIKPENLLVYEHQDGSKSLKLGDFGLATIVDGPLYTVCG-TPT-YVAPEIIAE 577
           S   +HRD+   N+LV E       LK+ DFGL+   D       G  P  ++APE + +
Sbjct: 379 SRKCIHRDLAARNVLVTEEH----VLKIADFGLSRTGDYYKKRSGGRLPVKWMAPEALFD 546

Query: 578 TGYGLKVDIWAAGVITY-ILLCGFPPFRGSGDDQEVLFDQILMGQVDFPSP 627
             Y  K D+W+ GV+ + I   G  P+  +    E L+ ++L      P P
Sbjct: 547 MRYTTKSDVWSFGVVLWEIFSLGGMPY--ASIPNEELYSKLLDDAYRMPRP 693
>26560
          Length = 398

 Score = 53.5 bits (127), Expect = 3e-07,   Method: Composition-based stats.
 Identities = 35/125 (28%), Positives = 62/125 (49%), Gaps = 2/125 (1%)
 Frame = -1

Query: 488 DLFDAITSTSKYTERDASGMLYNLASAIKYLHSLNIVHRDIKPENLLVYEHQDGSKSLKL 547
           DL   ++    +TE++       +   ++++HS  +V+RD+KP N+L+    D +  +++
Sbjct: 398 DLHYHLSQHGVFTEKEVRFYAAEVMLGLEHMHSRFVVYRDLKPANILL----DENGHVRI 231

Query: 548 GDFGLATIVDGPL-YTVCGTPTYVAPEIIAE-TGYGLKVDIWAAGVITYILLCGFPPFRG 605
            D GLA        +   GT  Y+APE++ +   Y    D ++ G + Y LL G  PFR 
Sbjct: 230 SDLGLACDFSKKRPHASVGTHGYMAPEVLMKGQSYDSSADWFSFGCMLYKLLKGHSPFRQ 51

Query: 606 SGDDQ 610
               Q
Sbjct: 50  HNQGQ 36
>20152
          Length = 445

 Score = 51.6 bits (122), Expect = 1e-06,   Method: Composition-based stats.
 Identities = 32/98 (32%), Positives = 49/98 (50%), Gaps = 1/98 (1%)
 Frame = +1

Query: 572 PEIIAETGY-GLKVDIWAAGVITYILLCGFPPFRGSGDDQEVLFDQILMGQVDFPSPYWD 630
           PEI+    Y    VD+W+ GVI Y+L+ G  PF+ + D + +    I+  +   P     
Sbjct: 1   PEILLGDSYDAPAVDVWSLGVILYMLVVGEAPFQEANDSETLTM--IMDCRYQIPP---- 162

Query: 631 NVSDSAKELINMMLLVNVDQRFSAVQVLEHPWVNDDGL 668
           ++S   ++LI  ML      R S   +L HPW+ND  L
Sbjct: 163 HISHKCQDLIEKMLQREPVDRASLPHILAHPWLNDGDL 276
>07291
          Length = 833

 Score = 50.8 bits (120), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 38/124 (30%), Positives = 59/124 (47%), Gaps = 16/124 (12%)
 Frame = +1

Query: 496 TSKYTERDASGMLY---------NLASAIKYLHSLNIVHRDIKPENLLVYEHQDGSKSLK 546
           TS+ T    S ML           +A  + YL  + +VHR++   N +V E  DG   L+
Sbjct: 4   TSRVTSAKPSKMLTVVQLLDFGRQIADGMAYLQEVKVVHRNLAARNCIVTE--DGR--LQ 171

Query: 547 LGDFGL-ATIVDGPLYTVCGTPT-----YVAPEIIAETGYGLKVDIWAAGVITYILLC-G 599
           L D+G+  ++     YT   +P      ++APE I    +  K D+WA GV+ + LL  G
Sbjct: 172 LSDYGVTGSLFPQSYYTADDSPARDLVKWMAPETIDNFHFSSKSDVWAFGVVLWELLTRG 351

Query: 600 FPPF 603
             P+
Sbjct: 352 ITPY 363
>11185
          Length = 473

 Score = 50.8 bits (120), Expect = 2e-06,   Method: Composition-based stats.
 Identities = 31/115 (26%), Positives = 50/115 (43%), Gaps = 25/115 (21%)
 Frame = +1

Query: 510 NLASAIKYLHSLNIVHRDIKPENLLVYEHQDGSKSLKLGDFGLATIVDGPLYTV------ 563
           +L + + Y+HSL I+  D++P  +L+    D S  LK  DFGL+ +    L  +      
Sbjct: 25  HLVTGLHYIHSLGILFHDLRPSKVLL----DTSGVLKFADFGLSKVEGENLEELFFKFAE 192

Query: 564 -------------------CGTPTYVAPEIIAETGYGLKVDIWAAGVITYILLCG 599
                               G+PTY+APE+       +  D+WA G + Y +  G
Sbjct: 193 AGDQWNIQSAEEMMKQVPTSGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFSG 357
>17722
          Length = 680

 Score = 49.7 bits (117), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 27/74 (36%), Positives = 40/74 (54%)
 Frame = -3

Query: 584 VDIWAAGVITYILLCGFPPFRGSGDDQEVLFDQILMGQVDFPSPYWDNVSDSAKELINMM 643
           VD W  GV+ Y ++CG  PF     D +VLF+ IL+  V FP     N+S+ AK L++ +
Sbjct: 678 VDWWGTGVVMYEMMCGRLPFYNR--DHDVLFELILLQNVKFPR----NLSEEAKTLLSGL 517

Query: 644 LLVNVDQRFSAVQV 657
           L  N  +R    + 
Sbjct: 516 LAKNPKRRLGGSEA 475
>19301
          Length = 712

 Score = 49.3 bits (116), Expect = 6e-06,   Method: Compositional matrix adjust.
 Identities = 33/124 (26%), Positives = 57/124 (45%)
 Frame = +2

Query: 428 TAREYALKIIKKSKCRGKEHMIQNEVSILRRVKHPNIVLLIEEMDVPTELYLVMELVKGG 487
            A E A+K ++  K        + ++  LR++ HPNI+             ++ME    G
Sbjct: 371 CAEEVAVKKVRDIK--------ETDIRNLRKLNHPNIISFKGVCTQAPCYCIIMEYCPYG 526

Query: 488 DLFDAITSTSKYTERDASGMLYNLASAIKYLHSLNIVHRDIKPENLLVYEHQDGSKSLKL 547
            L++ +    +            +AS + YLHS  I+HRD+K  N+LV ++      +K+
Sbjct: 527 QLYEVLRDGKEIPPALVLDWSKQIASGMNYLHSHKIIHRDLKSPNVLVAKND----VVKI 694

Query: 548 GDFG 551
            DFG
Sbjct: 695 SDFG 706
>07940
          Length = 1336

 Score = 48.5 bits (114), Expect = 9e-06,   Method: Compositional matrix adjust.
 Identities = 35/115 (30%), Positives = 52/115 (45%), Gaps = 11/115 (9%)
 Frame = -3

Query: 500 TERDASGMLYNLASAIKYLHSLNIVHRDIKPENLLVYEHQDGSKSLKLGDFGLA------ 553
           T +D     Y +A  ++YL S   +HRD+   N+LV E       LK+ DFGL       
Sbjct: 353 TPKDLISYAYQVARGMEYLASKQCIHRDLAARNVLVAEEY----VLKIADFGLTRNLQQF 186

Query: 554 ----TIVDGPLYTVCGTPTYVAPEIIAETGYGLKVDIWAAGVITY-ILLCGFPPF 603
                  DG L        ++APE + +  Y  K D+W+ GV+ + I   G  P+
Sbjct: 185 DYYRKTTDGRLPV-----KWMAPEALFDRKYTSKSDVWSYGVLLWEIFTLGGNPY 36
>12672
          Length = 773

 Score = 47.8 bits (112), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 44/134 (32%), Positives = 61/134 (45%), Gaps = 9/134 (6%)
 Frame = +3

Query: 512 ASAIKYLHSLNIVHRDIKPENLLVYEHQDGSKSLKLGDFGLATIVDGP---------LYT 562
           AS I+YL+    VHRDIK  N+L+    D   + K+GDF  AT+V  P            
Sbjct: 21  ASGIQYLNDNGHVHRDIKTANILL----DSEYTAKVGDF--ATVVSAPSGEGKTVQNASV 182

Query: 563 VCGTPTYVAPEIIAETGYGLKVDIWAAGVITYILLCGFPPFRGSGDDQEVLFDQILMGQV 622
           V GT  Y+APE I       K+D ++ GV+   ++ G      S   +E      +M  V
Sbjct: 183 VIGTAAYLAPEAI-HFDVSTKLDSYSFGVVLLEVITGLVAQDYS--REERTLSSHIMENV 353

Query: 623 DFPSPYWDNVSDSA 636
           + P    D V  SA
Sbjct: 354 EEPEEIHDFVDQSA 395
>21418
          Length = 831

 Score = 47.8 bits (112), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 24/57 (42%), Positives = 33/57 (57%), Gaps = 1/57 (1%)
 Frame = +2

Query: 616 QILMGQVDFPSPYWDNVSDSAKELINMMLLVNVDQRFSAVQVLEHPWVND-DGLPEN 671
           +I  GQ DFP P W NVS +AK+LI  ML V+  +R     VL + W+   D +P+ 
Sbjct: 11  RIRSGQYDFPDPEWTNVSQAAKDLIKGMLNVDPSKRLCIEDVLRNKWIAQYDAVPQT 181
>01106
          Length = 878

 Score = 47.8 bits (112), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 39/147 (26%), Positives = 75/147 (51%), Gaps = 16/147 (10%)
 Frame = +3

Query: 405 RYKVGRTIGDGNFAVVKECIERSTAREYALKIIKKSKCRGKEHMIQNEVSILRRVKHPNI 464
           RY V R +G G+F+ V  C + +  R  ALK++K ++   +  +  +EV +L+ V+  ++
Sbjct: 321 RYHVIRKLGWGHFSTVWLCWDLTCKRFVALKVVKSAQHYTETAL--DEVKLLKCVRESDV 494

Query: 465 --------VLLIEEMDVP----TELYLVMELVKGGDLFDAITSTSKYTE---RDASGMLY 509
                   V L+++  +     T + +V E++ G +L   I   S Y      +   ++ 
Sbjct: 495 ADPARAKCVQLLDDFKISGVNGTHVAMVFEVL-GYNLLKLIIR-SNYQGIPIHNVKLIIR 668

Query: 510 NLASAIKYLHS-LNIVHRDIKPENLLV 535
            +   + Y+H+   I+H DIKPEN+L+
Sbjct: 669 QVLEGLSYMHAKCRIIHTDIKPENILI 749
>26156
          Length = 479

 Score = 43.5 bits (101), Expect(2) = 2e-05,   Method: Compositional matrix adjust.
 Identities = 32/106 (30%), Positives = 48/106 (45%), Gaps = 3/106 (2%)
 Frame = -1

Query: 410 RTIGDGNFAVVKECIERSTAREYALKIIKKSKCRGKEHM--IQNEVSILRRV-KHPNIVL 466
           R IG G++A V +   + T R YA+K+IKK      E +  +Q E  +      +P +V 
Sbjct: 371 RVIGRGSYAKVLQVEHKRTKRIYAMKVIKKELVNDDEDIDWVQTEKHVFETATNYPFLVG 192

Query: 467 LIEEMDVPTELYLVMELVKGGDLFDAITSTSKYTERDASGMLYNLA 512
           L       + L+ V+E V GGDL   +    +  E  A   L   A
Sbjct: 191 LHSCFQSESRLFFVIEFVNGGDLMFHMQRQRRLPEEHARFTLLKSA 54

 Score = 23.1 bits (48), Expect(2) = 2e-05,   Method: Composition-based stats.
 Identities = 8/16 (50%), Positives = 12/16 (75%)
 Frame = -3

Query: 514 AIKYLHSLNIVHRDIK 529
           A+ +LH   IV+RD+K
Sbjct: 51  ALNFLHKRGIVYRDLK 4
>20655
          Length = 1181

 Score = 46.6 bits (109), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 21/49 (42%), Positives = 29/49 (59%)
 Frame = +2

Query: 620 GQVDFPSPYWDNVSDSAKELINMMLLVNVDQRFSAVQVLEHPWVNDDGL 668
           GQ +FP P W  VS  AK+LI  ML  + D+R +  QV+   WV D+ +
Sbjct: 23  GQYEFPKPEWSRVSQDAKDLIRGMLCTDPDKRLNIKQVMASKWVADNTM 169
>25019
          Length = 730

 Score = 45.8 bits (107), Expect = 6e-05,   Method: Composition-based stats.
 Identities = 27/63 (42%), Positives = 35/63 (55%), Gaps = 3/63 (4%)
 Frame = +3

Query: 531 ENLLVYEHQDGSKSLKLGDFGL---ATIVDGPLYTVCGTPTYVAPEIIAETGYGLKVDIW 587
           EN+L+    D    +KL DFGL   A       +T CGT  Y+APEI+  TG+G  VD W
Sbjct: 261 ENVLL----DKDGHVKLTDFGLCKEAITGTRVTHTFCGTIEYMAPEILTRTGHGKAVDWW 428

Query: 588 AAG 590
           + G
Sbjct: 429 SLG 437
>00715
          Length = 1788

 Score = 45.4 bits (106), Expect = 7e-05,   Method: Compositional matrix adjust.
 Identities = 54/206 (26%), Positives = 86/206 (41%), Gaps = 30/206 (14%)
 Frame = +1

Query: 430 REYALKIIKK--SKCRGKEHMIQNEVSILR-RVKHPNIVLLIEEMDV---PTELYLVMEL 483
           R  A+KI  K  S  R       NE+   R  ++H N+V ++    +       +L ME 
Sbjct: 1   RTVAVKIYHKRSSNPRALRQSYSNELLAFRCGLRHVNVVSILGATSLHRFEDGAWLAMEY 180

Query: 484 VKGGDLFDAITSTSKYTERDAS---GMLYNLASAIKYLHSLNIVHRDIKPENLLVYE--- 537
           V  G L           + D+S    +   +A  + YLHS+NIVH D+KP N L+     
Sbjct: 181 V--GPLNLQTILNDHQQDIDSSMRLSLALQMARGLHYLHSINIVHLDLKPANCLLTRDLK 354

Query: 538 ---------HQDGSKSLKLG--DFGLA------TIVDGPLYT-VCGTPTYVAPEIIAETG 579
                    HQ     L +G  + G+A      T V G     + GT  Y APE++    
Sbjct: 355 LRIADFGCCHQLTPTGLDMGEREGGMAGNELELTPVQGAWKNELAGTLAYRAPELLKGLQ 534

Query: 580 YGLKVDIWAAGVITYILLCGFPPFRG 605
             ++ D+++ G+  + +     P+ G
Sbjct: 535 PSVRSDVYSLGITLWQMCTRQGPYEG 612
>04138
          Length = 800

 Score = 45.1 bits (105), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 34/115 (29%), Positives = 52/115 (45%), Gaps = 7/115 (6%)
 Frame = +1

Query: 515 IKYLHSLNIVHRDIKPENLLVYEHQDGSKSLKLGDFGLATIVDGPL-----YT-VCGTPT 568
           + Y+H   I+HRD+K  N+L+ +       LKL DFGLA      L     YT    T  
Sbjct: 52  LYYIHRNKILHRDMKAANILITKQ----GVLKLADFGLARAFSVNLRQPNRYTNRVVTLW 219

Query: 569 YVAPE-IIAETGYGLKVDIWAAGVITYILLCGFPPFRGSGDDQEVLFDQILMGQV 622
           Y  PE ++ +  Y   +D W AG I   +    P  +G+ +  ++     L G +
Sbjct: 220 YRPPELLLGDRNYSTAIDQWGAGCIMAEMWTRNPIMQGTTEQNQLTLITQLCGSI 384
>18401
          Length = 463

 Score = 45.1 bits (105), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 32/142 (22%), Positives = 56/142 (39%), Gaps = 39/142 (27%)
 Frame = -3

Query: 562 TVCGTPTYVAPEIIAETGYGLKVDIWAAGVITYILLCGFPPFRGSGDDQEV-LFDQIL-- 618
           T+  T  Y APE+I E G+    D+W+ G I + L  G+  F+   + + + + ++IL  
Sbjct: 455 TIVSTRHYRAPEVILELGWSHPCDVWSVGCIMFELYTGYTLFQTHDNKEHLAMMERILGS 276

Query: 619 ----------------MGQVDFPS-------------PYWDNVSDSAK-------ELINM 642
                            G++D P              P    V D          +L+  
Sbjct: 275 LPYRMAKKTKKQKYFHHGRLDVPERSSMARYVRENTKPLLRYVKDRENKDHQQLFDLMKK 96

Query: 643 MLLVNVDQRFSAVQVLEHPWVN 664
           +L      R+S +Q L+HP+ +
Sbjct: 95  LLAYEASSRYSLLQALQHPFFS 30
>26009
          Length = 886

 Score = 44.3 bits (103), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 17/34 (50%), Positives = 26/34 (76%)
 Frame = +3

Query: 502 RDASGMLYNLASAIKYLHSLNIVHRDIKPENLLV 535
           R+A  ++  L SA+ ++HS  +VHRDIKPEN+L+
Sbjct: 711 REAKSVMKQLVSALDFMHSKQLVHRDIKPENVLI 812
>11404
          Length = 563

 Score = 44.3 bits (103), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 46/184 (25%), Positives = 82/184 (44%), Gaps = 22/184 (11%)
 Frame = +1

Query: 374 GDELGRR------HSLQRGWRREESEEGFQIPATITERYKVGRTIGDGNFAVVKECIERS 427
           GDE G +      H    G+     +          +RY++   IG G+F  V +  + +
Sbjct: 31  GDESGNKKNKVNAHVFNDGYDDANHDYIISPGEKWADRYEIDSLIGKGSFGQVVKAYDHT 210

Query: 428 TAREYALKIIKKSKCRGKEHMIQNEVSILRRVKHPN------IVLLIEEMDVPTELYLVM 481
              + A+KIIK  K    +  I  EV +L  +   +      IV L       + L LV 
Sbjct: 211 DNEQVAIKIIKNKKPFLNQAQI--EVKLLEMMNRHDTDNKYYIVRLKRHFMFRSHLCLVF 384

Query: 482 ELVKGGDLFDAITSTS----------KYTERDASGMLYNLASAIKYLHSLNIVHRDIKPE 531
           EL+   +L+D + +T+          K+ ++  + +L+ LA+       ++I+H D+KPE
Sbjct: 385 ELL-SYNLYDLLRNTNFRGVSLNLTRKFAQQLCTALLF-LATP-----EMSIIHCDLKPE 543

Query: 532 NLLV 535
           N+L+
Sbjct: 544 NILL 555
>36481
          Length = 806

 Score = 44.3 bits (103), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 35/136 (25%), Positives = 63/136 (46%), Gaps = 9/136 (6%)
 Frame = +2

Query: 413 GDGNFAVVKECIERSTAREYALKIIKK-SKCRGKEHMIQNEVSILRRVKHPN------IV 465
           G+G F  V +C +     + ALKIIK   K R    +   E+++L +++  +       V
Sbjct: 389 GEGTFGKVVQCKDLLKGDDIALKIIKNVDKYREAAKL---EINVLEKLREKDPHAKHMCV 559

Query: 466 LLIEEMDVPTELYLVMELVKGGDLFDAITSTS--KYTERDASGMLYNLASAIKYLHSLNI 523
            +++  D    + +   ++ G  +FD +   S   Y       + Y L  A+ +LH   +
Sbjct: 560 QMLDWFDYHGHVCISFHML-GLSVFDFLKDNSYGAYPIEQVRHISYQLCYAVNFLHENQL 736

Query: 524 VHRDIKPENLLVYEHQ 539
            H D+KPEN+L  + Q
Sbjct: 737 THTDLKPENILFVDSQ 784
>02638
          Length = 1490

 Score = 44.3 bits (103), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 27/97 (27%), Positives = 45/97 (46%)
 Frame = +1

Query: 565 GTPTYVAPEIIAETGYGLKVDIWAAGVITYILLCGFPPFRGSGDDQEVLFDQILMGQVDF 624
           GT  ++APE++    YG   D+W+ G +   +    PP+        +     +   VD 
Sbjct: 22  GTIAFMAPEVLRGESYGRACDVWSVGCVMIEMCTCRPPWNSHDISNHLALIFKIASSVD- 198

Query: 625 PSPYWDNVSDSAKELINMMLLVNVDQRFSAVQVLEHP 661
           P P  +N+S   ++L+   L  + D R SA  +L HP
Sbjct: 199 PPPIPENMSPPVRDLMLRCLEQDSDFRPSAKDLLMHP 309
>17253
          Length = 483

 Score = 43.9 bits (102), Expect = 2e-04,   Method: Composition-based stats.
 Identities = 37/141 (26%), Positives = 67/141 (47%), Gaps = 16/141 (11%)
 Frame = -1

Query: 429 AREY---ALKIIKKSKCRGKEHMIQNEVSILRRV-KHPNIVLLIEEMDVPTELYLVMELV 484
           AR++   A+K   ++    ++     E+SI+R++ +HPN+V  +    +     ++ME  
Sbjct: 477 ARQWDTVAVKTHNEAATDAEKSEFLRELSIMRKLPRHPNVVSFMGCCTMSDPALILMEFC 298

Query: 485 KGGDLFDAI-----------TSTSK-YTERDASGMLYNLASAIKYLHSLNIVHRDIKPEN 532
             GDL   +           TST+   T RD      ++A  + ++ +  IVHRD+   N
Sbjct: 297 CHGDLLSFLRKRRPDRTVFLTSTANDLTARDFFSFALHVARGMAHVANNKIVHRDVAARN 118

Query: 533 LLVYEHQDGSKSLKLGDFGLA 553
           +L+ E        K+ DFGL+
Sbjct: 117 VLISERN----VCKVSDFGLS 67
>37602
          Length = 804

 Score = 41.6 bits (96), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 25/75 (33%), Positives = 36/75 (48%)
 Frame = -1

Query: 476 ELYLVMELVKGGDLFDAITSTSKYTERDASGMLYNLASAIKYLHSLNIVHRDIKPENLLV 535
           +L++ ME   GG + D    T   TE   + +       + YLH    +HRDIK  N+L+
Sbjct: 297 KLWIAMEYCGGGSMQDIYHVTGPLTEPQIAFVCRETLKGLHYLHRRGKMHRDIKGANILL 118

Query: 536 YEHQDGSKSLKLGDF 550
            E  D    +KL DF
Sbjct: 117 TEEGD----VKLADF 85
>29360
          Length = 363

 Score = 38.9 bits (89), Expect = 0.008,   Method: Composition-based stats.
 Identities = 33/125 (26%), Positives = 59/125 (47%), Gaps = 11/125 (8%)
 Frame = +3

Query: 422 ECIERSTAREYALKIIKKSKCRGKEHMIQNEVSILRRVKHP-----NIVLLIEEMDVPTE 476
           +C ++ T+   A+KI+K      ++  I  EVSIL+R+        N V   E       
Sbjct: 6   KCWKKGTSEIVAIKILKNHPSYARQGQI--EVSILQRLSQESADDYNFVRAFECFQHKNH 179

Query: 477 LYLVMELVKGGDLFDAITSTS------KYTERDASGMLYNLASAIKYLHSLNIVHRDIKP 530
             LV E+++  +L+D +          KY       +L    +A++ L  L ++H D+KP
Sbjct: 180 TCLVFEMLEQ-NLYDFLKQNKFQPLPLKYIRPITQQVL----TALRKLKQLGLIHADLKP 344

Query: 531 ENLLV 535
           EN+++
Sbjct: 345 ENIML 359
>00638
          Length = 1595

 Score = 38.9 bits (89), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 22/57 (38%), Positives = 31/57 (54%)
 Frame = +2

Query: 479 LVMELVKGGDLFDAITSTSKYTERDASGMLYNLASAIKYLHSLNIVHRDIKPENLLV 535
           L+ E V   D F  +  T  +T+ D    LY L  A+ + HS+ I+HRD+KP   LV
Sbjct: 356 LIFEHVNNTD-FKQLYQT--FTDYDIRFYLYELMKALDFCHSMGIMHRDVKPSPPLV 517
>22005
          Length = 873

 Score = 38.5 bits (88), Expect = 0.009,   Method: Compositional matrix adjust.
 Identities = 46/213 (21%), Positives = 77/213 (36%), Gaps = 50/213 (23%)
 Frame = +1

Query: 435 KIIKKSKCRGKEHMIQNEVSILRRVKHPNIVLLIEEMDVPTELYLVMELVKGGDLFDAIT 494
           K++K+      +   + E S++    HPNIV L+    +   + L+ E +  GDL D + 
Sbjct: 109 KMLKEDASEDLQSDFEREASLMADFDHPNIVKLLGVCAIGKPMCLLFEFMSKGDLNDFLR 288

Query: 495 STS-----------------------------------KYTERDASGMLY---------N 510
             S                                   +  +RD SGML           
Sbjct: 289 LCSPENYNLPVSRSQNLVVDLEDGLRVEVEAEECEKDTQSEDRDCSGMLXTKDQLYISQQ 468

Query: 511 LASAIKYLHSLNIVHRDIKPENLLVYEHQDGSKSLKLGDFGLATIVDGPLYTVCGTPTYV 570
           +++ + YL   + VHRD     L        +    + DFGLA  V    Y   G+    
Sbjct: 469 ISAGMAYLAQKDYVHRD-----LATRTVXSRTT*S*ISDFGLARSVHSVDYYR-GSEQDA 630

Query: 571 AP------EIIAETGYGLKVDIWAAGVITYILL 597
            P      E I  + +  + D+W+ GV+ + +L
Sbjct: 631 IPIRWMPLEAILYSKFSTQSDVWSFGVVLWEIL 729
>17300
          Length = 480

 Score = 38.5 bits (88), Expect = 0.010,   Method: Compositional matrix adjust.
 Identities = 31/111 (27%), Positives = 54/111 (48%), Gaps = 8/111 (7%)
 Frame = +1

Query: 511 LASAIKYLHSLNIVHRDIKPENLLVYEHQDGSKSLKLGDFGLATIVDG----PLYTVCGT 566
           ++S +  L  +  VHRD+   N+LV E        K+ DFGL+  ++       YT  G 
Sbjct: 1   ISSGMGXLADMGYVHRDLAARNILVNEIL----VCKVADFGLSREIESDTTEGAYTTKGG 168

Query: 567 PT---YVAPEIIAETGYGLKVDIWAAGVITY-ILLCGFPPFRGSGDDQEVL 613
                + APE IA   +    D+W+ GV+ + ++  G  P+  +  +Q+V+
Sbjct: 169 KIPVRWTAPEAIAYRKFTSASDVWSFGVVMWEVMSYGERPYW-NWSNQDVI 318
>32957
          Length = 645

 Score = 38.5 bits (88), Expect = 0.011,   Method: Composition-based stats.
 Identities = 17/40 (42%), Positives = 23/40 (57%)
 Frame = +3

Query: 558 GPLYTVCGTPTYVAPEIIAETGYGLKVDIWAAGVITYILL 597
           G   T CGT  Y+APE+     YG +VD W  G++ + LL
Sbjct: 30  GRTRTFCGTREYMAPEVHERKEYGKEVDWWGLGILLHELL 149
>16708
          Length = 1397

 Score = 38.1 bits (87), Expect = 0.014,   Method: Compositional matrix adjust.
 Identities = 21/56 (37%), Positives = 32/56 (57%)
 Frame = -1

Query: 513  SAIKYLHSLNIVHRDIKPENLLVYEHQDGSKSLKLGDFGLATIVDGPLYTVCGTPT 568
             A++++H L +VH D+K +N+LV    D   + KL D+G+A      LY V   PT
Sbjct: 1061 CALEHIHELGVVHMDVKADNVLV----DAHGNCKLTDYGIAQ-----LYKVYPAPT 921
>17516
          Length = 453

 Score = 36.6 bits (83), Expect = 0.042,   Method: Composition-based stats.
 Identities = 15/39 (38%), Positives = 26/39 (66%), Gaps = 1/39 (2%)
 Frame = -3

Query: 562 TVCGTPTYVAPEIIAETG-YGLKVDIWAAGVITYILLCG 599
           T+ GTP Y+APE++ + G Y +K D+++  +I + L  G
Sbjct: 442 TLAGTPVYMAPEVLLQKGQYDMKADVYSLAIILWELWYG 326
>27274
          Length = 396

 Score = 35.4 bits (80), Expect = 0.089,   Method: Composition-based stats.
 Identities = 24/99 (24%), Positives = 46/99 (46%), Gaps = 8/99 (8%)
 Frame = -1

Query: 573 EIIAETGYGLKVDIWAAGVITYILLCGFPPF---RGS---GDDQEVLFDQILMGQVDFPS 626
           E++    +G  VD+W+ G++ + LL G  PF   RGS     +   ++ QI+ G      
Sbjct: 375 ELLRGQQHGPTVDMWSLGILLHELLSGHVPFEPERGSRQMARNMMAVYAQIIRGS---SR 205

Query: 627 PYWDN--VSDSAKELINMMLLVNVDQRFSAVQVLEHPWV 663
              D   +S    + +  ++ +   +R ++ Q   HPW+
Sbjct: 204 DVCDGLALSTHGADFLRRLVQLEDTKRLTSQQAFSHPWI 88
>07836
          Length = 1478

 Score = 35.0 bits (79), Expect = 0.10,   Method: Compositional matrix adjust.
 Identities = 38/119 (31%), Positives = 55/119 (46%), Gaps = 18/119 (15%)
 Frame = -1

Query: 475  TELYLVMELVKGGDLFDAITSTSKYTERDASGMLYNLASAIKYLHSLNI----------- 523
            T+L+L+ +  + G L D + S       D+S ML    SAI  L  L+I           
Sbjct: 1334 TQLFLITDYHENGSLHDYLLSRV----LDSSEMLALAHSAICGLAHLHIEIFGTRGKPAI 1167

Query: 524  VHRDIKPENLLVYEHQDGSKSLKLGDFGLAT-------IVDGPLYTVCGTPTYVAPEII 575
             HRDIK +N+LV   ++G+    + D GLA         VD       GT  Y+APE++
Sbjct: 1166 AHRDIKSKNILV--KKNGTCC--IADLGLAVRYISESNEVDVAPNPRQGTKRYMAPEVL 1002
>31120
          Length = 439

 Score = 35.0 bits (79), Expect = 0.11,   Method: Compositional matrix adjust.
 Identities = 26/92 (28%), Positives = 45/92 (48%), Gaps = 1/92 (1%)
 Frame = +1

Query: 573 EIIAETGYGLKV-DIWAAGVITYILLCGFPPFRGSGDDQEVLFDQILMGQVDFPSPYWDN 631
           E++    Y  K+ D W+ GVI +I+L G  PF  S  ++  L +     +  F     D 
Sbjct: 1   EVVCGVPYDPKMADAWSLGVILFIMLNGKMPFDDSNLNK--LLEDQRSKKYSFRRKLQDL 174

Query: 632 VSDSAKELINMMLLVNVDQRFSAVQVLEHPWV 663
           VS +A+  ++++L  N   R+   +VL   W+
Sbjct: 175 VSPNARSTVSVLLEPNSAMRWDLNEVLNCQWL 270
>33586
          Length = 551

 Score = 34.3 bits (77), Expect = 0.21,   Method: Composition-based stats.
 Identities = 14/36 (38%), Positives = 22/36 (61%)
 Frame = +2

Query: 476 ELYLVMELVKGGDLFDAITSTSKYTERDASGMLYNL 511
           +LYL++E ++GGDLF  ++    +TE D    L  L
Sbjct: 443 KLYLILEFLRGGDLFTRLSKEVMFTEEDVKFYLAEL 550
>21210
          Length = 518

 Score = 33.5 bits (75), Expect = 0.31,   Method: Compositional matrix adjust.
 Identities = 29/105 (27%), Positives = 47/105 (44%), Gaps = 6/105 (5%)
 Frame = +3

Query: 565 GTPTYVAPEII----AETGYGLKVDIWAAGVITYILLCGFPPFRGSGDDQEVLFDQI--L 618
           G   Y+APE I    +  GY ++ D+W+ G+    L  G  P+R        +FDQ+  +
Sbjct: 6   GCRPYMAPERIDPRASSHGYDVRSDVWSLGITLMELATGRFPYRKWVS----IFDQLQQV 173

Query: 619 MGQVDFPSPYWDNVSDSAKELINMMLLVNVDQRFSAVQVLEHPWV 663
           +  V    P+    S      +N  L  +  QR    ++L HP+V
Sbjct: 174 VRGVAPCLPHDGAFSHDFVNFVNKCLTKDEKQRPKYNKLLAHPFV 308
>21800
          Length = 855

 Score = 32.3 bits (72), Expect = 0.78,   Method: Compositional matrix adjust.
 Identities = 15/45 (33%), Positives = 26/45 (57%), Gaps = 1/45 (2%)
 Frame = +2

Query: 507 MLYNLASAIKYLHS-LNIVHRDIKPENLLVYEHQDGSKSLKLGDF 550
           ++  +   + YLH+  NI+H DIKPEN+L+    +  + L +  F
Sbjct: 647 IIRQVLEGLNYLHAKCNIIHTDIKPENILICVDDNYIRKLAVDAF 781
>18481
          Length = 437

 Score = 32.3 bits (72), Expect = 0.79,   Method: Composition-based stats.
 Identities = 27/112 (24%), Positives = 54/112 (48%), Gaps = 3/112 (2%)
 Frame = -1

Query: 445 KEHMIQNEVSILRRV-KHPNIVLLIEEMDVPTELYLVMELVKGG--DLFDAITSTSKYTE 501
           K  ++  E  +  ++ +HP +  +           LVMEL+     +LF  +    ++T 
Sbjct: 371 KHQLLHYEAKVYEQIGRHPGLPTMYHYGTEKHFNALVMELLGPSLEELF--VICKRRFTL 198

Query: 502 RDASGMLYNLASAIKYLHSLNIVHRDIKPENLLVYEHQDGSKSLKLGDFGLA 553
           +    +   L S ++++H    +HRD+KP+N L+   +   + L + DFGL+
Sbjct: 197 KTILMVSDQLLSRLEFIHQKCFIHRDLKPDNFLMGLGRHCHR-LYIIDFGLS 45
>20513
          Length = 405

 Score = 32.0 bits (71), Expect = 1.0,   Method: Composition-based stats.
 Identities = 16/43 (37%), Positives = 23/43 (53%), Gaps = 1/43 (2%)
 Frame = -1

Query: 629 WDNVSDSA-KELINMMLLVNVDQRFSAVQVLEHPWVNDDGLPE 670
           WD     A  + +  ML  + +QR +A Q L+HPW+  D  PE
Sbjct: 312 WDPKDAKAFADFLAPMLEFDPEQRATAAQSLQHPWLKLDA*PE 184
>17806
          Length = 433

 Score = 31.2 bits (69), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 22/85 (25%), Positives = 42/85 (49%), Gaps = 5/85 (5%)
 Frame = +1

Query: 410 RTIGDGNFA-VVKECIERSTA----REYALKIIKKSKCRGKEHMIQNEVSILRRVKHPNI 464
           + +G G F  V++   ER T      +  +K++K    + ++ +   EV+  R + HPNI
Sbjct: 67  KELGTGWFGKVIESDAERITTGVSRSKVVVKMLKDDATKDEQLLFFEEVAPFRELDHPNI 246

Query: 465 VLLIEEMDVPTELYLVMELVKGGDL 489
           V L+ +      + ++ME    G+L
Sbjct: 247 VRLLGQCTEMNPMLMLMECAALGNL 321
>16350
          Length = 1108

 Score = 31.2 bits (69), Expect = 1.8,   Method: Compositional matrix adjust.
 Identities = 16/43 (37%), Positives = 23/43 (53%), Gaps = 1/43 (2%)
 Frame = +3

Query: 629 WDNVSDSA-KELINMMLLVNVDQRFSAVQVLEHPWVNDDGLPE 670
           WD     A  + +  ML  + +QR +A Q L+HPW+  D  PE
Sbjct: 732 WDPKDAKAFADFLAPMLEFDPEQRATAAQSLQHPWLKLDA*PE 860
>16877
          Length = 823

 Score = 30.4 bits (67), Expect = 2.9,   Method: Composition-based stats.
 Identities = 15/36 (41%), Positives = 23/36 (63%)
 Frame = +1

Query: 116 KISSLDQLVEGESYVCGSIEPFKKLEYTKNVNPNWS 151
           KIS L   V  +SY+C +IEP  + + ++NVN  W+
Sbjct: 1   KISILKSDVTQKSYICLNIEPV-RCKVSRNVNLKWT 105
>09826
          Length = 725

 Score = 30.4 bits (67), Expect = 3.0,   Method: Composition-based stats.
 Identities = 18/81 (22%), Positives = 37/81 (45%)
 Frame = -3

Query: 137 FKKLEYTKNVNPNWSVNVKTTSASRAVSSLATAKGGPSEVRENKDFIRPKLVTIIRSGVK 196
            K++++     PN   N +T S ++       +    S+V+ N   ++  L  I  SGV 
Sbjct: 573 LKRIKWKNKCLPNTFYNCQTVSRAQGQKXFN*SDTDTSQVKFNSSRLQVSLSAIRSSGVD 394

Query: 197 PRKAVRILLNKKTAHSFEQVL 217
               ++ + N +  H F+++L
Sbjct: 393 WVNVLKFIHNGR*NHCFDEIL 331
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|46402179|ref|NP_997092.1| Sec24 related gene family,
member B [Mus musculus]
         (1251 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

27412                                                                 160   3e-39
11155                                                                  32   1.7  
28261                                                                  30   4.6  
>27412
          Length = 384

 Score =  160 bits (405), Expect = 3e-39,   Method: Compositional matrix adjust.
 Identities = 74/126 (58%), Positives = 103/126 (81%)
 Frame = +2

Query: 754 DLLNALPSMFINTRETHSALGPALQAAFKLMSPTGGRVSVFQTQLPSLGAGLLQSREDPN 813
           +LL  LP++F +  ET +ALG ALQAAFKLM+ TGGRV+V QT LP++G G L++RE  N
Sbjct: 2   ELLTQLPTLFEDNHETGNALGTALQAAFKLMTSTGGRVTVMQTTLPTVGPGSLENRE-AN 178

Query: 814 QRSSTKVVHHLGPATDFYKKLALDCSGQQTAVDLFLLSSQYSDLASLACMSKYSAGCIFY 873
            ++++    +LGP++DFYKKLALDCS QQ AVDLF+L+ QY+D+A+++C+SK+SAGC+ Y
Sbjct: 179 SKAASLNSAYLGPSSDFYKKLALDCSAQQIAVDLFMLNGQYADIATVSCISKFSAGCVQY 358

Query: 874 YPSFHS 879
           YPSFH+
Sbjct: 359 YPSFHT 376
>11155
          Length = 1328

 Score = 32.0 bits (71), Expect = 1.7,   Method: Compositional matrix adjust.
 Identities = 16/50 (32%), Positives = 28/50 (56%), Gaps = 3/50 (6%)
 Frame = +2

Query: 967  YTSSKGERRIRVHTLC---LPVVSSLADVYAGVDVQAAVCLLANMAVDRS 1013
            Y  S G+RR+RV T+        +++  + AG D +A+  L+  +AV R+
Sbjct: 128  YQHSSGQRRVRVTTVARNWADASTNIQHISAGFDQEASAVLMGRIAVYRA 277
>28261
          Length = 552

 Score = 30.4 bits (67), Expect = 4.6,   Method: Composition-based stats.
 Identities = 21/58 (36%), Positives = 31/58 (53%)
 Frame = -3

Query: 985  VVSSLADVYAGVDVQAAVCLLANMAVDRSVSSSLSDARDALVNAVVDPLSAYSSAVAS 1042
            VVS+L D    V V  A C+L NMA D  + +    A  +++ A + PLS  ++ V S
Sbjct: 232  VVSALXDERDEV-VANAACILTNMAQDEPLRAQAQKA--SVITAFIRPLSXSNTNVQS 68
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6678145|ref|NP_033305.1| signal sequence receptor,
delta [Mus musculus]
         (172 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

01610                                                                 156   4e-39
16900                                                                  56   6e-09
11381                                                                  47   4e-06
09831                                                                  26   7.7  
13147                                                                  26   8.7  
>01610
          Length = 712

 Score =  156 bits (394), Expect = 4e-39,   Method: Compositional matrix adjust.
 Identities = 71/144 (49%), Positives = 103/144 (71%)
 Frame = +1

Query: 28  PQITPSYYTTSDAVISTETVFIVEISLTCKNRVQNMALYADVSGKQFPVTRGQDVGRYQV 87
           PQ+T   YTT ++ +STETVFIVE S+TCKN ++N+ LYAD  GK  P ++  +  ++Q+
Sbjct: 37  PQVTSHTYTTPESTVSTETVFIVEFSVTCKNGLKNINLYADFGGKTVPASKIGEGNKFQL 216

Query: 88  SWSLEHKSAHAGTYEVRFFDEESYSLLRKAQRNNEDVSIIPPLFTVSVDHRGTWNGPWVS 147
           S + EHK   +GTY+VR FDEE Y+ LRKAQR+ E+   I PLFT+ + H G WNGP + 
Sbjct: 217 SLADEHKKLPSGTYQVRVFDEEGYAWLRKAQRSGENTDNIKPLFTLDLTHPGVWNGPLLQ 396

Query: 148 TEVLAAVIGIVIYYLAFSAKSHIQ 171
           +E LAA++ I +++ A++AKS +Q
Sbjct: 397 SEFLAAMVAIFVWWSAYTAKSRLQ 468
>16900
          Length = 371

 Score = 56.2 bits (134), Expect = 6e-09,   Method: Compositional matrix adjust.
 Identities = 25/41 (60%), Positives = 33/41 (80%)
 Frame = +3

Query: 28  PQITPSYYTTSDAVISTETVFIVEISLTCKNRVQNMALYAD 68
           PQ+T   YTT ++ +STETVFIVE S+TCKN ++N+ LYAD
Sbjct: 246 PQVTSHTYTTPESTVSTETVFIVEFSVTCKNGLENINLYAD 368
>11381
          Length = 628

 Score = 47.0 bits (110), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 20/34 (58%), Positives = 28/34 (82%)
 Frame = -3

Query: 35  YTTSDAVISTETVFIVEISLTCKNRVQNMALYAD 68
           +T  ++ +STETVFIVE S+TCKN ++N+ LYAD
Sbjct: 110 HTNPESTVSTETVFIVEFSVTCKNGLKNINLYAD 9
>09831
          Length = 1027

 Score = 26.2 bits (56), Expect = 7.7,   Method: Compositional matrix adjust.
 Identities = 21/86 (24%), Positives = 39/86 (45%), Gaps = 1/86 (1%)
 Frame = -1

Query: 69   VSGKQFPVTRGQDVGRYQVSWSLEHK-SAHAGTYEVRFFDEESYSLLRKAQRNNEDVSII 127
            + GK FP    +D   Y V W ++ + +A   +++  F   + Y   +  Q   +D ++ 
Sbjct: 1012 IEGKDFPSLSNKDNQEYLVKWGMKGRXTAQLYSFDQMF---QPYEKDQFVQDFFKDDNVT 842

Query: 128  PPLFTVSVDHRGTWNGPWVSTEVLAA 153
              L T+S    G W+   +S E + A
Sbjct: 841  STLQTLS--SSGKWSPVGLSAETVTA 770
>13147
          Length = 849

 Score = 25.8 bits (55), Expect = 8.7,   Method: Compositional matrix adjust.
 Identities = 19/70 (27%), Positives = 31/70 (44%)
 Frame = +2

Query: 41  VISTETVFIVEISLTCKNRVQNMALYADVSGKQFPVTRGQDVGRYQVSWSLEHKSAHAGT 100
           V+ST  V +V  +    + V    + AD+ GKQF V   Q +       ++E    +   
Sbjct: 407 VVSTSEVCLVRTNQQWPSPVHQAPVTADIVGKQFTVLERQRINNIA---TMEXHDENRRW 577

Query: 101 YEVRFFDEES 110
             + FF+E S
Sbjct: 578 LRITFFNETS 607
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|93102409|ref|NP_032014.3| fatty acid synthase [Mus
musculus]
         (2504 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

31408                                                                 161   4e-39
25131                                                                  65   5e-10
18797                                                                  64   9e-10
33940                                                                  54   1e-06
25428                                                                  39   0.026
21193                                                                  32   3.0  
11844                                                                  31   5.2  
>31408
          Length = 447

 Score =  161 bits (407), Expect = 4e-39,   Method: Compositional matrix adjust.
 Identities = 80/146 (54%), Positives = 102/146 (69%)
 Frame = +3

Query: 2031 NSTMERICEQRRHDGLPGLAVQWGAIGDVGIVLEAMGTNDTVIGGTLPQRISSCMEVLDL 2090
             S MERICE+R  DGLPGLAVQWGAIGDVG+VLE MG+NDTV+GGTLPQRI+SC+  LD 
Sbjct: 9    TSVMERICEKRAADGLPGLAVQWGAIGDVGVVLETMGSNDTVVGGTLPQRITSCLATLDR 188

Query: 2091 FLNQPHAVLSSFVLAEKKAVAHGDGDTQRDLVKAVAHILGIRDLAGINLDSTLADLGLDS 2150
            FLNQP  V+SS+V AEK+   +     ++ LV AVAH+LG++  A     +    L    
Sbjct: 189  FLNQPCPVMSSYVPAEKRTSKNEAAAGKQSLVDAVAHVLGVKA*AR*TPTAVWQTLVWTP 368

Query: 2151 LMGVEVRQILEREHDLVLPMREVRQL 2176
             +  E++Q LER+ DLV   R++RQL
Sbjct: 369  SLSTEIQQTLERDFDLVYSSRDIRQL 446
>25131
          Length = 982

 Score = 64.7 bits (156), Expect = 5e-10,   Method: Compositional matrix adjust.
 Identities = 45/158 (28%), Positives = 76/158 (48%)
 Frame = +3

Query: 1661 GETVLIHSGSGGVGQAAISIALSLGCRVFTTVGSAEKRAYLQARFPQLDDTSFANSRDTS 1720
            GETVL+H  SG VG A + IA ++G RV  T G+      ++        +   N R+  
Sbjct: 252  GETVLVHGASGAVGLACVQIAKAMGLRVLGTAGTPXGLDLVKTN----GASDVFNHREEG 419

Query: 1721 FEQHVLLHTGGKGVDLVLNSLAEEKLQASVRCLAQHGRFLEIGKFDLSNNHPLGMAIFLK 1780
            +  +++  TGG+G ++++  L+   LQ  +  +   GR + IG       +P  M    K
Sbjct: 420  YNANIMAATGGEGPNVIIEMLSNVNLQRDLEMVKFQGRIVVIGCRGTVEINPRLM--MGK 593

Query: 1781 NVTFHGILLDALFEEANDSWREVAALLKAGIRDGVVKP 1818
             +  +G++L +   E    W+E  A + AG   G +KP
Sbjct: 594  ELQVNGVMLPSSTPE---QWQEAHAFMFAGAECGWLKP 698
>18797
          Length = 1159

 Score = 63.5 bits (153), Expect = 9e-10,   Method: Compositional matrix adjust.
 Identities = 60/209 (28%), Positives = 94/209 (44%), Gaps = 26/209 (12%)
 Frame = -1

Query: 1603 GRRVMGLVPAEGLATSVLLSSDFL----WDV---PSSWTLEEAASVPVVYTTAYYSLVVR 1655
            G  V+G++P   L T+     +F     +DV   P   + EEAA+V      AY +L   
Sbjct: 889  GDEVVGILP---LDTTTSGCGEFCIFREFDVAKKPHRVSHEEAAAVIGDAVRAYTALHYH 719

Query: 1656 GRIQRGETVLIHSGSGGVGQAAISIALSLGCRVFTTVGSAEKRAYLQARFPQLDDTSFAN 1715
              +  G++VLI  G+   G  A+ +AL  G +V TT  S  ++ +L +  P +  T   N
Sbjct: 718  THVCAGDSVLIMDGATHAGSVAVQMALLWGAKVMTTYSSVPEKQFLDSFHPTVAQTMELN 539

Query: 1716 SRDTSFEQHVLLHTGGKGVDLVLN------------SLAEEKL-------QASVRCLAQH 1756
             R T     V+  TGG GVD +++            SL  EK        Q  + CL   
Sbjct: 538  QRSTLLVSTVMEETGGIGVDCIVDNGVRMFSNEEDVSLMGEKTKFPKPHKQDVLSCLGFS 359

Query: 1757 GRFLEIGKFDLSNNHPLGMAIFLKNVTFH 1785
            G+++   + DL  + P    +FL+N + H
Sbjct: 358  GKWV-TSQPDLQLDPPDSQQLFLRNASVH 275
>33940
          Length = 685

 Score = 53.5 bits (127), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 51/189 (26%), Positives = 88/189 (46%), Gaps = 12/189 (6%)
 Frame = +3

Query: 539 LSTDERTFDDIVHAFVSLTAIQIALIDLLTSVGLKPDGIIGHSLGEVACGYADGCLSQRE 598
           L  ++ T D+++   +++ A Q+ L  +  S+G++P  ++G SLGE+A  Y  GCLS  +
Sbjct: 42  LQQEDPTKDNVLSP-IAIFACQVGLAAVWQSLGVQPSCVVGQSLGEIAAAYLAGCLSLSD 218

Query: 599 AVLAAYWRGQCIKDAHLPPGSMAAVGLSWEECKQRCPAGV-----VPACHNSEDTVTISG 653
           AV   Y R Q +  A +  G+M  V        ++   G+     +   ++       S 
Sbjct: 219 AVXIIYHRSQLL--ASVTGGAMMVVQNVEVNQVRKVLTGMDDKASIALEYSPRACAISSD 392

Query: 654 PQAAVN---EFVEQLKQEGVFAKEVRTGGL----AFHSYFMEGIAPTLLQALKKVIREPR 706
           P+  +N     V QLK      K++R   L    A+HS  + G A  L + + K+   P+
Sbjct: 393 PETILNLRPTLVSQLKSTN---KDMRLIDLDVHVAYHSTHVNGAADKLKKQINKI--TPK 557

Query: 707 PRSARWLST 715
             S  + ST
Sbjct: 558 APSIPFYST 584
>25428
          Length = 866

 Score = 38.9 bits (89), Expect = 0.026,   Method: Compositional matrix adjust.
 Identities = 36/128 (28%), Positives = 54/128 (42%), Gaps = 3/128 (2%)
 Frame = +1

Query: 280 AGLAPESLEYIEAHGTGTKVGDPQELNGITRSLCAFRQAPLLIGSTKSNMGHPEPASGLA 339
           AG     + ++ AH T T +GD  E    +R++        ++ S K  +GH   A+G  
Sbjct: 4   AGEGEGEVGHVNAHATSTPIGDAVE----SRAIEGLLGPGTVVTSVKGALGHLLGAAGSV 171

Query: 340 ALTKVLLSLEHGVWAPNLHFHNPNPEIPALLDGRLQVVDRPLPVRGGNVGI---NSFGFG 396
                L S   G+  P  +   P  +    LD  +    RP   + G   I   NSFGFG
Sbjct: 172 EAIVTLQSCRTGIIPPTXNLSQP--DTAXHLD-YVTASPRPWQAKDGGRRIALTNSFGFG 342

Query: 397 GSNVHVIL 404
           G+N  + L
Sbjct: 343 GTNASLCL 366
>21193
          Length = 891

 Score = 32.0 bits (71), Expect = 3.0,   Method: Composition-based stats.
 Identities = 16/62 (25%), Positives = 26/62 (41%)
 Frame = -1

Query: 1986 KPKYNGTLNLDRATREACPELDYFVAFSSVSCGRGNAGQTNYGFANSTMERICEQRRHDG 2045
            KP       +D     AC  L +  + S  +      G+ ++GF +  +ER C+    DG
Sbjct: 525  KPACRQVFEVDGVRSFACTHLVHVSSISEKASQSWRTGEVDFGFCSFYLERNCKS*EFDG 346

Query: 2046 LP 2047
             P
Sbjct: 345  FP 340
>11844
          Length = 2366

 Score = 31.2 bits (69), Expect = 5.2,   Method: Compositional matrix adjust.
 Identities = 14/38 (36%), Positives = 23/38 (60%)
 Frame = +3

Query: 1746 LQASVRCLAQHGRFLEIGKFDLSNNHPLGMAIFLKNVT 1783
            LQ ++ C+  H   +   K  LSNN+PL + I L+N++
Sbjct: 1413 LQVNLNCIFHHRNSIHNSKHILSNNNPLYLNITLQNIS 1526
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6680836|ref|NP_031617.1| calreticulin [Mus musculus]
         (416 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

30091                                                                 157   5e-39
22772                                                                  83   1e-17
21776                                                                  28   4.9  
>30091
          Length = 447

 Score =  157 bits (398), Expect = 5e-39,   Method: Compositional matrix adjust.
 Identities = 77/112 (68%), Positives = 91/112 (81%), Gaps = 1/112 (0%)
 Frame = -2

Query: 18  DPAIYFKEQFLDGDAWTNRWVESKHKS-DFGKFVLSSGKFYGDLEKDKGLQTSQDARFYA 76
           +P  +F E+F +G  W +RW +S HK  + GKF LS+GKFYGD EKDKG+QTSQDARFY 
Sbjct: 332 EPTTHFVEKFEEG--WESRWTDSTHKGGEQGKFKLSAGKFYGDAEKDKGIQTSQDARFYG 159

Query: 77  LSAKFEPFSNKGQTLVVQFTVKHEQNIDCGGGYVKLFPSGLDQKDMHGDSEY 128
           LSAKF+ FSN+G+TLV+QFTVKHEQNIDCGGGY K+F S LDQ DMHGDS Y
Sbjct: 158 LSAKFDTFSNEGKTLVIQFTVKHEQNIDCGGGYAKIFSSDLDQADMHGDSPY 3
>22772
          Length = 365

 Score = 82.8 bits (203), Expect(2) = 1e-17,   Method: Compositional matrix adjust.
 Identities = 42/64 (65%), Positives = 45/64 (70%)
 Frame = +1

Query: 224 KIDDPTDSKPEDWDKPEHIPDPDAKKXXXXXXXXXXXXXXXVIQNPEYKGEWKPRQIDNP 283
           KI DP D KPEDWDKPEHIPDPDAKK               +I NPEY+GEWKP+QIDNP
Sbjct: 124 KIADPEDKKPEDWDKPEHIPDPDAKKPDDWDDEMDGEWEPPMIDNPEYQGEWKPKQIDNP 303

Query: 284 DYKG 287
           DYKG
Sbjct: 304 DYKG 315

 Score = 24.6 bits (52), Expect(2) = 1e-17,   Method: Composition-based stats.
 Identities = 9/11 (81%), Positives = 11/11 (100%)
 Frame = +3

Query: 291 HPEIDNPEYSP 301
           HPEIDNP+Y+P
Sbjct: 327 HPEIDNPDYTP 359
>21776
          Length = 452

 Score = 28.5 bits (62), Expect = 4.9,   Method: Compositional matrix adjust.
 Identities = 10/17 (58%), Positives = 13/17 (76%)
 Frame = +2

Query: 291 HPEIDNPEYSPDANIYA 307
           HP +DNP+ SP AN Y+
Sbjct: 359 HPVLDNPQTSPSANXYS 409
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|94386628|ref|XP_001005289.1| PREDICTED: protein
tyrosine phosphatase, non-receptor type 23 isoform 5 [Mus musculus]
         (1692 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

28978                                                                 160   5e-39
19713                                                                 144   2e-34
19387                                                                 100   4e-21
15655                                                                  82   1e-15
30741                                                                  72   1e-12
19962                                                                  65   2e-10
26948                                                                  57   6e-08
29613                                                                  57   6e-08
17840                                                                  55   3e-07
17631                                                                  52   3e-06
34628                                                                  30   9.1  
>28978
          Length = 438

 Score =  160 bits (404), Expect = 5e-39,   Method: Compositional matrix adjust.
 Identities = 74/145 (51%), Positives = 108/145 (74%), Gaps = 1/145 (0%)
 Frame = -1

Query: 206 ISAQVVDYYKEACRALENPDTASLLG-RIQKDWKKLVQMKIYYFAAVAHLHMGKQAEEQQ 264
           +SAQVVD+Y+ A + L+  +   ++  R  KDW+K +++K  ++  + H ++ +Q+EEQ 
Sbjct: 438 VSAQVVDFYRLALKNLDQCNAEQIINSRSFKDWRKRIELKTAFYQCITHYYVARQSEEQS 259

Query: 265 KFGERVAYFQSALDKLNEAIKLAKGQPDTVQDALRFAMDVIGGKYNSAKKDNDFIYHEAV 324
           ++G+R+AY Q+A  KLN+A+KLAK +   +Q+ALRFA DV+GGK  SA+KDNDFIYHE +
Sbjct: 258 RWGDRLAYLQAAELKLNDALKLAKNEVPEMQEALRFAQDVVGGKLQSAQKDNDFIYHEKI 79

Query: 325 PALDTLQPVKGAPLVKPLPVNPTDP 349
           P LDTL  VKGAPLVK +P +PTDP
Sbjct: 78  PPLDTLPEVKGAPLVKGIPFDPTDP 4
>19713
          Length = 417

 Score =  144 bits (364), Expect = 2e-34,   Method: Composition-based stats.
 Identities = 72/134 (53%), Positives = 90/134 (67%)
 Frame = +3

Query: 1247 LDAIWRELQEAQEHDARGRSIAIARCYSLKNRHQDVMPYDSNRVVLRSGKDDYINASCVE 1306
            LD  W+ L ++Q+HD + +SIAIARCY +KNR  D+MPYD  RVVL + KDDYINAS + 
Sbjct: 12   LDTAWKSLIDSQDHDLKKQSIAIARCYPMKNRDPDIMPYDETRVVLSTTKDDYINASWIN 191

Query: 1307 GLSPYCPPLVATQAPLPGTAADFWLMVHEQKVSVIVMLVSEAEMEKQKVARYFPTERGQP 1366
             L+P CP  VATQAPL  T  DFW MV+E    VIV + SE E  K K   Y+PTE+GQ 
Sbjct: 192  DLAPSCPKFVATQAPLNVTMMDFWDMVYELGSEVIVQITSEYETSK-KFPVYYPTEKGQA 368

Query: 1367 MVHGALSVALSSIR 1380
            M  G + V L S++
Sbjct: 369  MEQGPMIVTLQSVK 410
>19387
          Length = 570

 Score =  100 bits (250), Expect = 4e-21,   Method: Compositional matrix adjust.
 Identities = 71/191 (37%), Positives = 107/191 (56%), Gaps = 2/191 (1%)
 Frame = -3

Query: 426 AALSVRPDTVKNLVQSMQVLSGVFTDVEASLKDIRDXXXXXXXXXXXXXXXXXXAGAGPG 485
           AA+SVR + +K+LV +M  +SG+ T+ E ++ +I                         G
Sbjct: 550 AAMSVRTNAIKDLVDAMSGVSGLATETEMNINEITQHDR*GR*KTAEFQKQF-------G 392

Query: 486 PSVAKAELAEVRREWAKYMEVHEKASFTNSELHRAMNLHVGNLRLLSGPLDQVRAALPTP 545
             +  + L  + R+   + E H + S  N+ LH AMN H+ NLRLL+ P DQ++A LP P
Sbjct: 391 KKMESSVLPGLSRDCEGHQERHAQGSQLNASLHTAMNAHIANLRLLALPPDQLQAQLPPP 212

Query: 546 AL--TPEDKAVLQNLKRILAKVQEMRDQRVSLEQQLRELIQKDDITASLVTTDHSEMKKL 603
                PED AVL  ++R+L KV+EM+ QR +LE+Q R+ I  DDIT  L+  D S    +
Sbjct: 211 QPPRNPEDDAVLTEMRRLLGKVEEMKVQRATLEKQFRDDIHNDDITTVLMAAD-STKDSV 35

Query: 604 FEEQLKKYDQL 614
           +++QLKK+D L
Sbjct: 34  YKDQLKKHDTL 2
>15655
          Length = 467

 Score = 82.4 bits (202), Expect = 1e-15,   Method: Composition-based stats.
 Identities = 50/154 (32%), Positives = 80/154 (51%), Gaps = 9/154 (5%)
 Frame = +1

Query: 1349 EMEKQKVARYFPTERGQPMVHGALSVALSSIRTTETHVERVLSLQFRDQSLKRSLVHLHF 1408
            E ++ K  +Y+P E           V   S++T + +VE  L L+  +    R + HL F
Sbjct: 7    ERQRMKCGQYWPFEEQSDEQFEEFLVDNKSVQTYKNYVETKLILRNTETDEWREVTHLQF 186

Query: 1409 PTWPELGLPDSPG--NLLRFIQEVHAHYLHQ-------RPLHTPIVVHCSSGVGRTGAFA 1459
             +WP+ G+P + G  + L  ++EV A    +        PL  PIVVHCS+G+GRTG F 
Sbjct: 187  ISWPDYGIPPATGFLDFLFHVREVQASATTKMGASWAGHPLGPPIVVHCSAGIGRTGTFI 366

Query: 1460 LLYAAVQEVEAGNGIPELPQLVRRMRQQRKHMLQ 1493
             +  +++ +E   G  ++P  VRR+R QR   +Q
Sbjct: 367  TIDISLRRLE-DTGTVDVPVTVRRIRSQRAFSIQ 465
>30741
          Length = 506

 Score = 72.4 bits (176), Expect = 1e-12,   Method: Composition-based stats.
 Identities = 41/118 (34%), Positives = 61/118 (51%)
 Frame = -3

Query: 1388 RVLSLQFRDQSLKRSLVHLHFPTWPELGLPDSPGNLLRFIQEVHAHYLHQRPLHTPIVVH 1447
            RV+ ++   QS  R + H HF  WP+ G P+    LL F+  V AH  H      P +VH
Sbjct: 456  RVIDIKLGSQS--RMIKHFHFMRWPDHGCPERTSMLLNFVSSVRAHMPHTGA--GPTLVH 289

Query: 1448 CSSGVGRTGAFALLYAAVQEVEAGNGIPELPQLVRRMRQQRKHMLQEKLHLKFCHEAL 1505
            CS+GVGRTG F  L   + ++     + ++  LV  MR  R +M+Q +    + H+ L
Sbjct: 288  CSAGVGRTGTFIALDRLLLQIRQQTEV-DIFNLVLTMRDNRMYMVQTENQYVYIHDCL 118
>19962
          Length = 410

 Score = 65.5 bits (158), Expect = 2e-10,   Method: Composition-based stats.
 Identities = 45/138 (32%), Positives = 71/138 (51%), Gaps = 7/138 (5%)
 Frame = +1

Query: 1370 GALSVALSSIRTTETHVERVLSL-QFRDQS----LKRSLVHLHFPTWPELGLPDSPGNLL 1424
            G  +V  + +      V R+L++ Q  DQ+    + R +  LHF  WP+ G+P  P  L+
Sbjct: 16   GRYTVTSTKVFHRAHFVHRLLTVSQATDQNTGGGVSREVHLLHFTAWPDHGVP-CPVTLV 192

Query: 1425 RFIQEVHAHYLHQRP--LHTPIVVHCSSGVGRTGAFALLYAAVQEVEAGNGIPELPQLVR 1482
            RF       Y+ ++P  L  P++VHCS+G+GRTG +  L     + E    +   P  VR
Sbjct: 193  RFWS-----YVTRQPAQLSGPLLVHCSAGIGRTGTYIALDMLTHQAETTGKVSVFPT-VR 354

Query: 1483 RMRQQRKHMLQEKLHLKF 1500
            R+R QR +M+Q     +F
Sbjct: 355  RIRGQRVNMVQTISQYRF 408
>26948
          Length = 2380

 Score = 57.0 bits (136), Expect = 6e-08,   Method: Compositional matrix adjust.
 Identities = 38/121 (31%), Positives = 61/121 (50%), Gaps = 5/121 (4%)
 Frame = -1

Query: 153  AFAYLREHFPQAFSVDMSRQILTLNVNLMLGQAQECLLEKSMLDNRKSFLV-----ARIS 207
             F YL  HF  A S+DM    L++   L+L QAQEC++E+ ++   K  +V     AR +
Sbjct: 2380 GFKYLESHFRNAPSMDMQSDTLSMLCVLLLAQAQECVMEERLMQWGKEGVVVNAQLAREA 2201

Query: 208  AQVVDYYKEACRALENPDTASLLGRIQKDWKKLVQMKIYYFAAVAHLHMGKQAEEQQKFG 267
            A V + Y+E  R + +    S L      W  + Q K Y++  +AH ++     EQ+  G
Sbjct: 2200 AMVSEKYRETHRKMSSEAVKSYLPF---PWISMAQTKHYFYKGLAHYYVAMALLEQKDSG 2030

Query: 268  E 268
            +
Sbjct: 2029 D 2027
>29613
          Length = 425

 Score = 57.0 bits (136), Expect = 6e-08,   Method: Composition-based stats.
 Identities = 39/111 (35%), Positives = 54/111 (48%), Gaps = 3/111 (2%)
 Frame = -2

Query: 1388 RVLSLQFRDQSLKRSLVHLHF-PTWPELGLPDSPGNLLRFIQEVHAHYLHQRPLHTPIVV 1446
            R  ++   DQ  +   V  +F P W +     SP ++L FI  V    L  R    P+VV
Sbjct: 343  RTFTIYKEDQEDESRQVKQYFIPGWEDYSANLSPDDVLDFISSVR---LESRGCQGPMVV 173

Query: 1447 HCSSGVGRTGAFALLYAAVQEVEAG--NGIPELPQLVRRMRQQRKHMLQEK 1495
            HCS+GVGRTG F  L   +Q V     N   ++  LV  MR  R +M+Q +
Sbjct: 172  HCSAGVGRTGTFIALDFLMQFVRDHDLNDEVDIYNLVLNMRHNRPYMVQSE 20
>17840
          Length = 437

 Score = 54.7 bits (130), Expect = 3e-07,   Method: Composition-based stats.
 Identities = 30/94 (31%), Positives = 53/94 (56%)
 Frame = +1

Query: 1416 LPDSPGNLLRFIQEVHAHYLHQRPLHTPIVVHCSSGVGRTGAFALLYAAVQEVEAGNGIP 1475
            +PD    +L F+Q+  A      P   PIVVHCS+GVGRTG + L+ + ++++   + + 
Sbjct: 1    VPDYTLPVLEFVQKSAAC---NPPDGGPIVVHCSAGVGRTGTYILIDSMIRQIGDKHTV- 168

Query: 1476 ELPQLVRRMRQQRKHMLQEKLHLKFCHEALVRHV 1509
             +P     +R+QR  ++Q +    F H+ LV ++
Sbjct: 169  NIPGFTLHIRRQRNLLVQTEDQYMFIHDVLVEYL 270
>17631
          Length = 442

 Score = 51.6 bits (122), Expect = 3e-06,   Method: Composition-based stats.
 Identities = 43/146 (29%), Positives = 68/146 (46%), Gaps = 4/146 (2%)
 Frame = +2

Query: 1364 GQPMVHGALSVALSSIRTTETHVERVLSLQFR-DQSLKRSLVHLHFPTWPELGLPDSPGN 1422
            G P  HG ++V L S R       R LS+     + L  + VH+H   W   G   +P +
Sbjct: 8    GVPQRHGDVTVVLKSRRDLGHCTVRSLSVAMMLHEPLHVTHVHMH--GWLTEGDTVAPED 181

Query: 1423 LLRFIQEVHAHYLHQRPLHTPIVVHCSSGVGRTGAFA---LLYAAVQEVEAGNGIPELPQ 1479
            LL+ +  V     H      PI VHCSSG GRTG +    +L+  V E    + I ++  
Sbjct: 182  LLKVVSLVRQAARH---CQGPITVHCSSGTGRTGVYIAVDILHGLVSENSLDSEI-DVFS 349

Query: 1480 LVRRMRQQRKHMLQEKLHLKFCHEAL 1505
            L   +   R +++Q +   ++ HE++
Sbjct: 350  LCHTLMTCRPNIIQSQDQYEYVHESV 427
>34628
          Length = 545

 Score = 30.0 bits (66), Expect = 9.1,   Method: Composition-based stats.
 Identities = 13/33 (39%), Positives = 20/33 (60%)
 Frame = +1

Query: 103 KSVSHEDIKYEQACILYNLGALHSMLGAMDKRV 135
           + V  EDIK +    L+ LG +H+M G +DK +
Sbjct: 61  QDVLEEDIKGDLVSTLHQLGQMHTMAGDIDKAI 159
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|94370595|ref|XP_987709.1| PREDICTED: similar to
[Segment 1 of 2] Traf2 and NCK-interacting kinase [Mus musculus]
         (1360 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

18921                                                                 159   7e-39
12721                                                                 122   1e-27
14420                                                                 112   9e-25
00300                                                                 110   5e-24
37602                                                                  90   1e-22
13212                                                                  96   3e-20
19094                                                                  97   4e-20
13592                                                                  90   8e-18
01431                                                                  82   2e-15
01707                                                                  80   5e-15
01060                                                                  80   7e-15
01756                                                                  76   1e-13
04852                                                                  72   1e-12
14126                                                                  72   1e-12
01718                                                                  71   3e-12
01966                                                                  69   2e-11
03240                                                                  69   2e-11
06405                                                                  68   3e-11
19301                                                                  66   1e-10
17975                                                                  65   2e-10
11780                                                                  64   3e-10
17253                                                                  64   5e-10
16708                                                                  63   9e-10
29581                                                                  62   2e-09
14116                                                                  61   3e-09
09606                                                                  61   3e-09
27405                                                                  60   6e-09
00392                                                                  60   6e-09
30755                                                                  59   1e-08
21808                                                                  59   2e-08
15910                                                                  53   5e-08
12786                                                                  55   1e-07
26560                                                                  55   2e-07
21079                                                                  54   4e-07
18484                                                                  53   8e-07
04591                                                                  53   1e-06
13066                                                                  52   1e-06
28638                                                                  37   2e-06
09007                                                                  51   2e-06
00715                                                                  51   3e-06
14477                                                                  51   3e-06
07940                                                                  48   2e-05
27546                                                                  48   3e-05
07836                                                                  46   1e-04
31885                                                                  46   1e-04
24241                                                                  45   2e-04
07291                                                                  45   2e-04
19761                                                                  45   2e-04
26711                                                                  45   3e-04
04138                                                                  44   3e-04
31489                                                                  42   0.002
11404                                                                  42   0.002
36481                                                                  42   0.002
28157                                                                  42   0.002
01392                                                                  41   0.003
20559                                                                  40   0.005
03508                                                                  40   0.007
18481                                                                  40   0.007
12672                                                                  39   0.013
21433                                                                  38   0.024
25019                                                                  37   0.037
29360                                                                  37   0.055
28865                                                                  36   0.097
32359                                                                  34   0.33 
17300                                                                  34   0.37 
01106                                                                  33   0.58 
21800                                                                  33   0.75 
15741                                                                  33   0.97 
26009                                                                  32   1.2  
02717                                                                  30   5.0  
11185                                                                  30   8.9  
>18921
          Length = 697

 Score =  159 bits (402), Expect = 7e-39,   Method: Composition-based stats.
 Identities = 82/183 (44%), Positives = 117/183 (63%)
 Frame = +2

Query: 16  SALRDPAGIFELVELVGNGTYGQVYKGRHVKTGQLAAIKVMDVTGDEEEEIKQEINMLKK 75
           S  R P  +F+++  +G G+YG V+K  H +TGQ+ AIK + V  D +E IK EI+++++
Sbjct: 8   SLARPPEDVFDILGKLGEGSYGSVFKSLHKETGQVLAIKQVPVDTDLQEIIK-EISIMQQ 184

Query: 76  YSHHRNIATYYGAFIKKNPPGMDDQLWLVMEFCGAGSVTDLIKNTKGNTLKEEWIAYICR 135
               + I  YYG++ K      +  LW+VME+CGAGSV+D+++  +  TL E  IA I  
Sbjct: 185 -CDSKYIVKYYGSYFK------NTDLWIVMEYCGAGSVSDIMR-LRNKTLVEREIATILY 340

Query: 136 EILRGLSHLHQHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWM 195
             L+GL +LH  + IHRDIK  N+LL      KL DFGV+ QL  T+ +RNT IGTPYWM
Sbjct: 341 YTLKGLXYLHSRRKIHRDIKAGNILLNNEGHAKLADFGVAGQLTDTMAKRNTVIGTPYWM 520

Query: 196 APK 198
           AP+
Sbjct: 521 APE 529
>12721
          Length = 821

 Score =  122 bits (306), Expect = 1e-27,   Method: Composition-based stats.
 Identities = 76/234 (32%), Positives = 127/234 (54%), Gaps = 19/234 (8%)
 Frame = +1

Query: 20  DPAGIFELVELVGNGTYGQVYKGRHVKTGQLAAIKVMDVTGDEEEEIK-QEINMLKKYSH 78
           DP    +    +G G+ G V      + G+  A+K MD+   +  E+   E+ +++ Y H
Sbjct: 79  DPRTFLDDFMKIGEGSTGIVCIATS-RDGRQMAVKKMDLRKQQRRELLFNEVVVMRDY-H 252

Query: 79  HRNIATYYGAFIKKNPPGMDDQLWLVMEFCGAGSVTDLIKNTKGNTLKEEWIAYICREIL 138
           H NI   Y +++      ++D+LW+VMEF   G++TD++ N   N + E  IA +CR  L
Sbjct: 253 HPNIVEMYNSYL------VNDELWVVMEFMEGGALTDIVTN---NRMDEVQIATVCRACL 405

Query: 139 RGLSHLHQHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPK 198
           + L+ LH + VIHRDIK  ++LL+ + +VKL DFG  AQ+ + + +R + +GTPYWMAP+
Sbjct: 406 KALAFLHANGVIHRDIKSDSILLSHDGKVKLXDFGFCAQVTQDLQKRKSLVGTPYWMAPE 585

Query: 199 SLPVMRTRMPH-----------MISRVTCG---LWESPPL----RWQKVPPPSV 234
            +    +R+P+           M+  +       +  PPL    R + +PPP +
Sbjct: 586 VI----SRLPYGPEVDIWSLGIMVMEMIDAEPPFFNEPPLQAMRRIRDMPPPKL 735
>14420
          Length = 528

 Score =  112 bits (280), Expect = 9e-25,   Method: Composition-based stats.
 Identities = 56/145 (38%), Positives = 89/145 (61%)
 Frame = +2

Query: 54  KVMDVTGDEEEEIKQEINMLKKYSHHRNIATYYGAFIKKNPPGMDDQLWLVMEFCGAGSV 113
           K M+++   ++E+     ++ + + + NI  Y  +++      + ++LW+VMEF   GS+
Sbjct: 2   KTMNLSQQPKKELIINEILVMRENQNPNIVNYLDSYL------VGEELWVVMEFLAGGSL 163

Query: 114 TDLIKNTKGNTLKEEWIAYICREILRGLSHLHQHKVIHRDIKGQNVLLTENAEVKLVDFG 173
           TD++  T    + E  IA +CRE L+ L  LH+++VIHRDIK  N+LL  +  VKL DFG
Sbjct: 164 TDVVTET---CMDEGQIAAVCRECLQALEFLHENQVIHRDIKSDNILLGMDGSVKLTDFG 334

Query: 174 VSAQLDRTVGRRNTFIGTPYWMAPK 198
             AQL     +R+T +GTPYWMAP+
Sbjct: 335 FCAQLSPEQSKRSTMVGTPYWMAPE 409
>00300
          Length = 2318

 Score =  110 bits (274), Expect = 5e-24,   Method: Compositional matrix adjust.
 Identities = 57/173 (32%), Positives = 96/173 (55%), Gaps = 5/173 (2%)
 Frame = -1

Query: 31   VGNGTYGQVYKGRHVKTGQLAAIKVMDVTGDEEEEIKQEINMLKKYS--HHRNIATYYGA 88
            +G G +G+VY   ++ TG+L A+K M    ++ +++++  + +K +    H N+  YYG 
Sbjct: 1634 IGEGQFGKVYTAVNMSTGELMALKEMKFQPNDLQQLREMCDEIKIFEGIQHENLVKYYGV 1455

Query: 89   FIKKNPPGMDDQLWLVMEFCGAGSVTDLIKNTKGNTLKEEWIAYICREILRGLSHLHQHK 148
             + K      D++ + ME+C  G++ +  K      L E  I    REI+  ++HLH++ 
Sbjct: 1454 EVHK------DEMLMFMEYCDTGTIEEAAKMG----LPEYLIRRYTREIVLAVNHLHENS 1305

Query: 149  VIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTV---GRRNTFIGTPYWMAPK 198
            ++HRDIKG N+ LT N  VKL DFG S +L       G  +  +GT  +MAP+
Sbjct: 1304 IVHRDIKGANIFLTSNGHVKLGDFGCSVKLKSHTTMPGEFHNLVGTTAYMAPE 1146
>37602
          Length = 804

 Score = 90.1 bits (222), Expect(2) = 1e-22,   Method: Composition-based stats.
 Identities = 55/126 (43%), Positives = 75/126 (59%), Gaps = 7/126 (5%)
 Frame = -1

Query: 74  KKYSHHR--NIATYYGAFIKKNPPGMDDQLWLVMEFCGAGSVTDLIKNTKGNTLKEEWIA 131
           KK+S  R  NI T+ G F   +     ++LW+ ME+CG GS+ D+   T    L E  IA
Sbjct: 372 KKFS**RIVNIQTFVGYF---DSYLRREKLWIAMEYCGGGSMQDIYHVT--GPLTEPQIA 208

Query: 132 YICREILRGLSHLHQHKVIHRDIKGQNVLLTENAEVKLVDF-GVSAQLDRTVGRR----N 186
           ++CRE L+GL +LH+   +HRDIKG N+LLTE  +VKL DF  VS+     V ++    N
Sbjct: 207 FVCRETLKGLHYLHRRGKMHRDIKGANILLTEEGDVKLADFWRVSSNHSHNVQKKVFHWN 28

Query: 187 TFIGTP 192
            FIG P
Sbjct: 27  AFIGWP 10

 Score = 35.8 bits (81), Expect(2) = 1e-22,   Method: Composition-based stats.
 Identities = 14/25 (56%), Positives = 19/25 (76%)
 Frame = -2

Query: 19  RDPAGIFELVELVGNGTYGQVYKGR 43
           R+P   FEL++ VG+GTYG VYK +
Sbjct: 521 RNPLDDFELIQRVGSGTYGDVYKAK 447

 Score = 43.9 bits (102), Expect(2) = 8e-05,   Method: Composition-based stats.
 Identities = 19/29 (65%), Positives = 24/29 (82%)
 Frame = -1

Query: 171 DFGVSAQLDRTVGRRNTFIGTPYWMAPKS 199
           DFGVSAQ+  T+ +R +FIGTPYWMA K+
Sbjct: 744 DFGVSAQITATMCKRKSFIGTPYWMARKN 658

 Score = 21.6 bits (44), Expect(2) = 8e-05,   Method: Composition-based stats.
 Identities = 9/13 (69%), Positives = 11/13 (84%)
 Frame = -2

Query: 158 NVLLTENAEVKLV 170
           N+LLTE  +VKLV
Sbjct: 803 NILLTEEGDVKLV 765

 Score = 32.0 bits (71), Expect = 1.6,   Method: Composition-based stats.
 Identities = 14/26 (53%), Positives = 18/26 (69%)
 Frame = -2

Query: 172 FGVSAQLDRTVGRRNTFIGTPYWMAP 197
           FGVSAQ+  T+ +R +FIGTP    P
Sbjct: 86  FGVSAQITATMCKRKSFIGTPLLDGP 9
>13212
          Length = 1067

 Score = 95.5 bits (236), Expect(2) = 3e-20,   Method: Composition-based stats.
 Identities = 44/74 (59%), Positives = 54/74 (72%)
 Frame = -1

Query: 125 LKEEWIAYICREILRGLSHLHQHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGR 184
           + E  I Y+C E+   L  LH+H VIHRDIK  NVLLT + EVKL DFGVSA+  +T  +
Sbjct: 989 MTEAQICYVCHEMCMALDFLHRHHVIHRDIKAGNVLLTIDGEVKLADFGVSAKNTQTQQK 810

Query: 185 RNTFIGTPYWMAPK 198
           R+TFIGTPYWMAP+
Sbjct: 809 RDTFIGTPYWMAPE 768

 Score = 22.7 bits (47), Expect(2) = 3e-20,   Method: Composition-based stats.
 Identities = 6/10 (60%), Positives = 8/10 (80%)
 Frame = -2

Query: 101  LWLVMEFCGA 110
            LW+ +EFCG 
Sbjct: 1057 LWMFLEFCGG 1028
>19094
          Length = 898

 Score = 97.4 bits (241), Expect = 4e-20,   Method: Composition-based stats.
 Identities = 47/90 (52%), Positives = 60/90 (66%)
 Frame = +1

Query: 109 GAGSVTDLIKNTKGNTLKEEWIAYICREILRGLSHLHQHKVIHRDIKGQNVLLTENAEVK 168
           GAGSV+D+++  +  TL E  IA I    L+GL +LH  + IHRDIK  N+LL      K
Sbjct: 4   GAGSVSDIMR-LRNKTLVEREIATILYYTLKGL*YLHSRRKIHRDIKAGNILLNNEGHAK 180

Query: 169 LVDFGVSAQLDRTVGRRNTFIGTPYWMAPK 198
           L DFGV+ QL  T+ +RNT IGTPYWMAP+
Sbjct: 181 LADFGVAGQLTDTMAKRNTVIGTPYWMAPE 270
>13592
          Length = 980

 Score = 89.7 bits (221), Expect = 8e-18,   Method: Composition-based stats.
 Identities = 56/175 (32%), Positives = 95/175 (54%), Gaps = 7/175 (4%)
 Frame = +2

Query: 31  VGNGTYGQVYKGRHVKTGQLAAIKVMDVTGDEEEEIK---QEINMLKKYSHHRNIATYYG 87
           +G G +G+VY   +  TG+L A+K + +   E   +K   +E+ +L+   H +N+  YYG
Sbjct: 8   IGQGRFGKVYTAVNNNTGELMAMKEIAIQPGETRALKNVAEELKILEGIKH-KNLVRYYG 184

Query: 88  AFIKKNPPGMDDQLWLVMEFCGAGSVTDLIKNTKGNTLKEEWIAYICREILRGLSHLHQH 147
             + +      ++L + ME C  G++  L++ T G  L E        ++L G++ LH+H
Sbjct: 185 IEVHR------EELLIFMELCSEGTLESLVELTGG--LPEALSRRFTAQLLSGVAELHKH 340

Query: 148 KVIHRDIKGQNVLLTENA-EVKLVDFG--VSAQLDRTV-GRRNTFIGTPYWMAPK 198
            ++HRDIK  N+ L + +  +KL DFG  V  Q   TV G    ++GT  +MAP+
Sbjct: 341 GIVHRDIKTANIFLVDGSNSLKLGDFGSAVKIQAHTTVPGELQGYVGTQAYMAPE 505
>01431
          Length = 1309

 Score = 82.0 bits (201), Expect = 2e-15,   Method: Compositional matrix adjust.
 Identities = 79/297 (26%), Positives = 123/297 (41%), Gaps = 3/297 (1%)
 Frame = +3

Query: 1041 NTRNASIQKYFVQLYGVXTFWWGLKMAXCFWTEVAKAKXXXXXXXXXXXRWMCXKDXMFL 1100
            + R+ SI+++ V+  GV       +M  C+   +A+A+           +W C +   + 
Sbjct: 9    SIRSVSIRRFSVRHSGVSIC*LAPRMDSCYSIVLARARSIS*SRVGVSNKWRC*RVKTYW 188

Query: 1101 SRYQERRTSSVCTISHGXETESCTMTQ---KWKRSRAGSLSVTWKAASITKSLNMKESSS 1157
            S Y+ +R      I  G     C       KW  +  G + V +K   I +  N +  SS
Sbjct: 189  SPYRAKRIVFASIICRGLSPRFCAPMASPIKWNVAMVGLMLVIYKVLYILRLSNTRGLSS 368

Query: 1158 WXLPXRMQXRYMRGPLNLTISSWHLSLLQIFSISLCSLTSQXKKVKGXRSYLAHTLVSMX 1217
              L  +   ++M G  N   + WHL +L  ++I+     SQ +  +  + ++    VSM 
Sbjct: 369  **LH*KTLLKFMHGRPNHITNLWHLRILVNWNIAPFWSISQLRISRD*K*FMVPLRVSMR 548

Query: 1218 LMLILETPTISIYHPIFRAISLLMLSSSCLKQMEWRCLSAMRMKGCTXTPTAGSLRMWCS 1277
            L+ I    TI I+  I R  S  ++      Q       AM M+    T      R  C 
Sbjct: 549  LI*IRLKYTIYIFLSILRVQSFRIVLWRFQIQTVCXYCCAMTMRASMXTLPDVYPRTLCC 728

Query: 1278 NGEKCPHLWPTFIPIRXWAGARKLLRSGQWKQDIWMECLCINELKGXSFYVKEMIRY 1334
            +G KCP  WPT    R WAGA K  R    +  IWM CLC       + +   M +Y
Sbjct: 729  SGAKCPPRWPTLALXRLWAGAIKQ*RYVPLRAAIWMVCLCTRRRNA*NSFASAMTKY 899
>01707
          Length = 757

 Score = 80.5 bits (197), Expect = 5e-15,   Method: Composition-based stats.
 Identities = 56/180 (31%), Positives = 93/180 (51%), Gaps = 4/180 (2%)
 Frame = +1

Query: 25  FELVELVGNGTYGQVYKGRHVKTGQLAAIKVMDVTGDEEEEIKQ----EINMLKKYSHHR 80
           +E +  +G G+YG V+K R+ +T QL AIK   V  +++  IK+    EI MLK+  H  
Sbjct: 70  YEKIGKIGEGSYGVVFKCRNKETSQLVAIKKF-VESEDDPLIKKIAMREIRMLKQLKH-P 243

Query: 81  NIATYYGAFIKKNPPGMDDQLWLVMEFCGAGSVTDLIKNTKGNTLKEEWIAYICREILRG 140
           N+      F +K       +L LV ++     + +L +  +G  L E  +  I  + L  
Sbjct: 244 NLVRLIEVFRRKK------RLHLVFDYVDHTLLNELDRYPRG--LPEPMVKRIIYQTLLA 399

Query: 141 LSHLHQHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPKSL 200
           ++  HQ+  IHRD+K +N+L+T   +VKL DFG +  L         ++ T ++ AP+ L
Sbjct: 400 VNFCHQYNTIHRDVKPENILITRQGQVKLCDFGFARILTGPGDEYTDYVATRWYRAPELL 579
>01060
          Length = 1800

 Score = 79.7 bits (195), Expect = 7e-15,   Method: Composition-based stats.
 Identities = 52/173 (30%), Positives = 86/173 (49%), Gaps = 3/173 (1%)
 Frame = +1

Query: 31  VGNGTYGQVYKGRHVKTGQLAAIKVMDVTGDEE---EEIKQEINMLKKYSHHRNIATYYG 87
           +G GTYG VYK RH  TG+  A+K + + G E+       +EI ML++   H NI     
Sbjct: 97  IGEGTYGVVYKCRHRATGRKLAMKKIRLRGSEDGVPSSAIREIAMLREL-RHTNIVCLED 273

Query: 88  AFIKKNPPGMDDQLWLVMEFCGAGSVTDLIKNTKGNTLKEEWIAYICREILRGLSHLHQH 147
             ++      D++L+LV EF        + K  +G  L    +     +I+ G+   HQ 
Sbjct: 274 VIME------DERLFLVFEFLSMDLKMYIDKFPEGVVLDRRLVKSYVFQIVTGIXFCHQR 435

Query: 148 KVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPKSL 200
           +++HRD+K QN+L+     +K+ DFG++      V      + T ++ AP+ L
Sbjct: 436 RIVHRDLKPQNLLINHTGAIKIADFGMARTFALPVRAYTHEVVTLWYRAPEIL 594
>01756
          Length = 1858

 Score = 75.9 bits (185), Expect = 1e-13,   Method: Compositional matrix adjust.
 Identities = 48/165 (29%), Positives = 86/165 (52%), Gaps = 9/165 (5%)
 Frame = -3

Query: 20   DPAGIFELVELVGNGTYGQVYKGRHVKTGQLAAIKVMDVTGDEEEE-----IKQEINMLK 74
            D    +E +  +G GT+G+V+K R  KT Q+ A+K   V  D E+E       +EI +L+
Sbjct: 1751 DEDAKYEKLAKIGQGTFGEVFKARCKKTKQVVAMK--KVLMDNEKEGFPITALREIKILQ 1578

Query: 75   KYSHHRNIATYYGAFIKKNPPG-MDDQLWLVMEFCG---AGSVTDLIKNTKGNTLKEEWI 130
              +H   +        K           +LV EFC    AG ++++        +KE   
Sbjct: 1577 LLNHENVVDLIEICSTKATSANRYKSMFYLVFEFCEHDLAGLLSNMSVVFNLPEIKE--- 1407

Query: 131  AYICREILRGLSHLHQHKVIHRDIKGQNVLLTENAEVKLVDFGVS 175
              + ++++ GL ++H++K++HRD+K  N+L+T+   +KL DFG++
Sbjct: 1406 --VMKQLMNGLYYIHRNKILHRDMKAANILITKQGVLKLADFGLA 1278
>04852
          Length = 1462

 Score = 72.4 bits (176), Expect = 1e-12,   Method: Compositional matrix adjust.
 Identities = 56/206 (27%), Positives = 91/206 (44%), Gaps = 27/206 (13%)
 Frame = +1

Query: 42  GRHVKTGQLAAIKVMD-VTGDEEEEIKQEINMLK---KYSHHRNIATYYGAFIKKNPPGM 97
           GR  K   +A   + D VT  EE++  QE+ ++K   K   H NI  + G   +  P   
Sbjct: 4   GRVPKASTVAVKMLRDIVTAVEEQDFVQELQVMKAVKKMGSHINIVNFLGCCTQGGP--- 174

Query: 98  DDQLWLVMEFCGAGSVTDLIKNTK-----------------------GNTLKEEWIAYIC 134
              LW+++EF   G++ D +++ +                       G+ ++ + +    
Sbjct: 175 ---LWVIVEFAKNGNLRDFLESCRDGINGYGKFVSPQDPGWYTKTPGGHVIRRKNLLSYA 345

Query: 135 REILRGLSHLHQHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYW 194
            +I RG+  L   K IHRD+  +NVL+TE   +K+ DFG+S   D    R    +    W
Sbjct: 346 FQIARGMEFLASRKCIHRDLAARNVLVTEEHVLKIADFGLSRTGDYYKKRSGGRLPVK-W 522

Query: 195 MAPKSLPVMRTRMPHMISRVTCGLWE 220
           MAP++L  MR      +      LWE
Sbjct: 523 MAPEALFDMRYTTKSDVWSFGVVLWE 600
>14126
          Length = 1265

 Score = 72.0 bits (175), Expect = 1e-12,   Method: Compositional matrix adjust.
 Identities = 47/156 (30%), Positives = 83/156 (53%), Gaps = 5/156 (3%)
 Frame = +3

Query: 25  FELVELVGNGTYGQVYKGRHVKT-GQLAAIKVMDVTGDEEEE---IKQEINMLKKYSHHR 80
           +E V ++GNG YG VYK R ++  G+  A+K + +   EE       +EI+MLK+   + 
Sbjct: 195 YEEVAVIGNGAYGTVYKARDLRNQGEFVAMKRIRLNNTEEGMPMMAIREISMLKQLEQYE 374

Query: 81  NIATYYGAFIKKNP-PGMDDQLWLVMEFCGAGSVTDLIKNTKGNTLKEEWIAYICREILR 139
           +        +  N     + +L LV E+      T L K      L  + I  +  ++L 
Sbjct: 375 HPNVVRLLDVSHNTITDREIRLNLVFEYIEHDLATYLAK-CPSPGLGPDRIKDLMLQLLN 551

Query: 140 GLSHLHQHKVIHRDIKGQNVLLTENAEVKLVDFGVS 175
           G+  LH ++++HRD+K QN+L++++  +KL DFG++
Sbjct: 552 GVDFLHSNRIVHRDLKPQNLLISKDGRLKLADFGLA 659
>01718
          Length = 959

 Score = 71.2 bits (173), Expect = 3e-12,   Method: Compositional matrix adjust.
 Identities = 49/184 (26%), Positives = 93/184 (50%), Gaps = 10/184 (5%)
 Frame = +3

Query: 27  LVELVGNGTYGQVYKGRHVKTGQLAAIKVMDVTGDEEEEIKQEINMLKKYSHHRNIATYY 86
           + E +G G + +V+K  H  TGQ+ A+K+  +T +    ++ E+ +L +  H  NI  + 
Sbjct: 159 ICEKIGAGFFSEVFKVTHRITGQVMALKMNTMTSNRHNMLR-EVQLLNRLQH-ANILRFM 332

Query: 87  GAFIKKNPPGMDDQLWLVMEFCGAGSVTDLIKNTKGNTLKEEWIAYICREIL-----RGL 141
           G  + +       QL  + E+  +G++  L++       K+E + +  R  L     RGL
Sbjct: 333 GVCVHEG------QLHALTEYIPSGNLEQLLEK------KDEELPWTQRIQLTLGLARGL 476

Query: 142 SHLHQHKVIHRDIKGQNVLL----TENAEVKLVDFGVSAQLDRTVGRRNT-FIGTPYWMA 196
            +LH  + IHRD+  +N+L+           + DFG++ ++   + +     +G+PYWMA
Sbjct: 477 DYLHSTRFIHRDLTSKNILIRREDNHGYHAVIADFGLATKIPDPLDKEKLPTVGSPYWMA 656

Query: 197 PKSL 200
           P+ L
Sbjct: 657 PEVL 668
>01966
          Length = 1735

 Score = 68.6 bits (166), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 44/161 (27%), Positives = 78/161 (48%), Gaps = 3/161 (1%)
 Frame = -1

Query: 43   RHVKTGQLAAIKVMDVTGDEE---EEIKQEINMLKKYSHHRNIATYYGAFIKKNPPGMDD 99
            RH  TG+  A+K + + G E+       +EI ML++   H NI       ++      D+
Sbjct: 1651 RHRATGRKLAMKKIRLRGSEDGVPSSAIREIAMLREL-RHTNIVCLEDVIME------DE 1493

Query: 100  QLWLVMEFCGAGSVTDLIKNTKGNTLKEEWIAYICREILRGLSHLHQHKVIHRDIKGQNV 159
            +L+LV EF        + K  +G  L    +     +I+ G++  HQ +++HRD+K QN+
Sbjct: 1492 RLFLVFEFLSMDLKMYIDKFPEGVVLDRRLVKSYVFQIVTGINFCHQRRIVHRDLKPQNL 1313

Query: 160  LLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPKSL 200
            L+     +K+ DFG++      V      + T ++ AP+ L
Sbjct: 1312 LINHTGAIKIADFGMARTFALPVRAYTHEVVTLWYRAPEIL 1190
>03240
          Length = 1683

 Score = 68.6 bits (166), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 44/155 (28%), Positives = 78/155 (50%), Gaps = 4/155 (2%)
 Frame = -3

Query: 24   IFELVELVGNGTYGQVYKGRHVKTGQLAAIKVM---DVTG-DEEEEIKQEINMLKKYSHH 79
            +FE ++ +G G +G+V   R   TG L A+K +   DV   ++   +K E ++L +  + 
Sbjct: 1288 MFEKIKTLGVGAFGEVSLCRKNDTGMLYAMKTLRKSDVLKRNQVAHVKAERDILAEADNE 1109

Query: 80   RNIATYYGAFIKKNPPGMDDQLWLVMEFCGAGSVTDLIKNTKGNTLKEEWIAYICREILR 139
              +  YY +F   N       L+ VM++   G +  L+   +   L E    +   E+++
Sbjct: 1108 WVVKLYY-SFQDHN------YLYFVMDYVPGGDLMGLL--IRMEILDEPLARFYVAELVQ 956

Query: 140  GLSHLHQHKVIHRDIKGQNVLLTENAEVKLVDFGV 174
             +  +H+   IHRDIK  N+L+  N  +KL DFG+
Sbjct: 955  AIESVHRMGFIHRDIKPDNILIDRNGHIKLTDFGL 851
>06405
          Length = 1965

 Score = 67.8 bits (164), Expect = 3e-11,   Method: Compositional matrix adjust.
 Identities = 47/194 (24%), Positives = 87/194 (44%), Gaps = 4/194 (2%)
 Frame = +1

Query: 31  VGNGTYGQVYKGRHVKTGQLAAIKVMDVTGDEEEEIKQEINMLKKYSHHRNIATYYGAFI 90
           +G G YG VY+    +  ++ A+K +        +  +E  ++K+  H  N+    G   
Sbjct: 283 LGGGQYGDVYEAMWKRYNKIVAVKTLKEDTMALNDFLEEAAIMKEMKH-PNLVQLLGVCT 459

Query: 91  KKNPPGMDDQLWLVMEFCGAGSVTDLIKNTKGNTLKEEWIAYICREILRGLSHLHQHKVI 150
           ++ P       ++V EF   G++ D ++++         + Y+  +I  G+++L     I
Sbjct: 460 REPP------FYIVTEFMPHGNLLDYLRSSTREENGPTALMYMATQIASGMAYLETKNFI 621

Query: 151 HRDIKGQNVLLTENAEVKLVDFGVSAQL-DRTVGRRNTFIGTPY---WMAPKSLPVMRTR 206
           HRD+  +N L+ ++  VK+ DFG++  + D T       IG  +   W AP+ L   R  
Sbjct: 622 HRDLAARNCLVADSNMVKVADFGLARLMKDDTY---TAHIGAKFPIKWTAPEGLAFNRFS 792

Query: 207 MPHMISRVTCGLWE 220
               I      LWE
Sbjct: 793 TRSDIWAFGVLLWE 834
>19301
          Length = 712

 Score = 65.9 bits (159), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 43/148 (29%), Positives = 80/148 (54%)
 Frame = +2

Query: 28  VELVGNGTYGQVYKGRHVKTGQLAAIKVMDVTGDEEEEIKQEINMLKKYSHHRNIATYYG 87
           +E +G+G  G V+ G+ +   ++A  KV D+        + +I  L+K +H  NI ++ G
Sbjct: 320 LEWLGSGAQGAVFLGK-LCAEEVAVKKVRDIK-------ETDIRNLRKLNH-PNIISFKG 472

Query: 88  AFIKKNPPGMDDQLWLVMEFCGAGSVTDLIKNTKGNTLKEEWIAYICREILRGLSHLHQH 147
              +           ++ME+C  G + +++++  G  +    +    ++I  G+++LH H
Sbjct: 473 VCTQAPC------YCIIMEYCPYGQLYEVLRD--GKEIPPALVLDWSKQIASGMNYLHSH 628

Query: 148 KVIHRDIKGQNVLLTENAEVKLVDFGVS 175
           K+IHRD+K  NVL+ +N  VK+ DFG S
Sbjct: 629 KIIHRDLKSPNVLVAKNDVVKISDFGTS 712
>17975
          Length = 449

 Score = 65.5 bits (158), Expect = 2e-10,   Method: Composition-based stats.
 Identities = 47/147 (31%), Positives = 73/147 (49%), Gaps = 4/147 (2%)
 Frame = +3

Query: 36  YGQVYKGRHVKTGQLAAIKVMDVTGDEE---EEIKQEINMLKKYSHHRNIATYYGAFIKK 92
           +  V   RHV TG+  A+KV+D T  +E     + QE+  +K    H N+   Y     +
Sbjct: 6   FAVVKLARHVFTGEKVAVKVIDKTKLDEVSRSHLFQEVRCMK-LVQHPNVVRLYEVIDTQ 182

Query: 93  NPPGMDDQLWLVMEFCGAGSVTDLIKNTKGNTLKEEWIAYICREILRGLSHLHQHKVIHR 152
                  +L+L++E    G + D I    G  L+E+      R+I+  +S+ H+  V+HR
Sbjct: 183 T------KLYLILELGDGGDMYDYIMRHSGG-LEEKLAKRYFRQIVEAISYCHKLHVVHR 341

Query: 153 DIKGQNVLLTEN-AEVKLVDFGVSAQL 178
           D+K +NV+  E    VKL DFG S  L
Sbjct: 342 DLKPENVVFFEKPGLVKLTDFGFSTCL 422
>11780
          Length = 1713

 Score = 64.3 bits (155), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 44/177 (24%), Positives = 87/177 (49%), Gaps = 1/177 (0%)
 Frame = +3

Query: 25  FELVELVGNGTYGQVYKGRHVKTGQLAAIKVMDVTGDEEEEIKQEINMLKKYSHHRNIAT 84
            E+ E +G G +G VYKG +   GQ  AIK +      E+   QE +++    H  N+  
Sbjct: 603 LEIGEAIGKGDFGDVYKGMY--RGQPVAIKQLKDKDRGEQSFLQEASVMTSLRHD-NLVR 773

Query: 85  YYGAFIKKNPPGMDDQLWLVMEFCGAGSVTDLIKNTKGNTLKEEWIAYICREILRGLSHL 144
             G  + +        ++LV EF G G++ + +++   + + ++       +    + +L
Sbjct: 774 LIGVVLGET-------IFLVTEFMGKGNLVEYLRSRGRSVITKKDQINFATDTCAAMEYL 932

Query: 145 HQHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPY-WMAPKSL 200
              +++HRD+  +NVL+ ++ + K+ DFG++   D +     T +  P  W AP++L
Sbjct: 933 ESKRLVHRDLAARNVLVHDDGKAKVSDFGLAKFGDFS----QTSVKFPIKWTAPEAL 1091
>17253
          Length = 483

 Score = 63.5 bits (153), Expect = 5e-10,   Method: Composition-based stats.
 Identities = 40/155 (25%), Positives = 73/155 (47%), Gaps = 12/155 (7%)
 Frame = -1

Query: 44  HVKTGQLAAIKVMD--VTGDEEEEIKQEINMLKKYSHHRNIATYYGAFIKKNPPGMDDQL 101
           H +     A+K  +   T  E+ E  +E+++++K   H N+ ++ G         M D  
Sbjct: 480 HARQWDTVAVKTHNEAATDAEKSEFLRELSIMRKLPRHPNVVSFMGCCT------MSDPA 319

Query: 102 WLVMEFCGAGSVTDLIKNTK----------GNTLKEEWIAYICREILRGLSHLHQHKVIH 151
            ++MEFC  G +   ++  +           N L           + RG++H+  +K++H
Sbjct: 318 LILMEFCCHGDLLSFLRKRRPDRTVFLTSTANDLTARDFFSFALHVARGMAHVANNKIVH 139

Query: 152 RDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRN 186
           RD+  +NVL++E    K+ DFG+S    R VG +N
Sbjct: 138 RDVAARNVLISERNVCKVSDFGLS----RRVGDQN 46
>16708
          Length = 1397

 Score = 62.8 bits (151), Expect = 9e-10,   Method: Compositional matrix adjust.
 Identities = 40/161 (24%), Positives = 81/161 (50%), Gaps = 6/161 (3%)
 Frame = -1

Query: 27   LVELVGNGTYGQVYKGRHVKTGQLAAIKVMDVTGDEEEEIKQEINMLKKYSHHRNIATYY 86
            +++++G G +G+VY+ R + T + AA+K   +     +E++     L +      +A  +
Sbjct: 1391 ILQVLGKGVFGKVYEARLLSTHEKAALKTSILCHHSLDEVEA----LGRIEGGFYLAQMF 1224

Query: 87   GAFIKKNP-PGMDDQLWLVMEFCGAGSVTDLIKNTKGNTLKEEW-----IAYICREILRG 140
            GA++   P P M+    +++ F   G + ++  + K   +   W     +  I  + +  
Sbjct: 1223 GAWVTCLPFPKMN----ILLHFYEMGPLCNVYAHYKNKEMPIRWSNPAMVCCIAGQXVCA 1056

Query: 141  LSHLHQHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRT 181
            L H+H+  V+H D+K  NVL+  +   KL D+G+ AQL + 
Sbjct: 1055 LEHIHELGVVHMDVKADNVLVDAHGNCKLTDYGI-AQLYKV 936
>29581
          Length = 1278

 Score = 61.6 bits (148), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 37/122 (30%), Positives = 63/122 (51%)
 Frame = -2

Query: 79   HRNIATYYGAFIKKNPPGMDDQLWLVMEFCGAGSVTDLIKNTKGNTLKEEWIAYICREIL 138
            H+NI       + K+     D L+LVME+C    +  L+ N       E  +  I  ++L
Sbjct: 1178 HQNIVQLQEVVVGKSL----DSLFLVMEYC-EQDLASLLDNMPA-PFSESQVKCIVLQLL 1017

Query: 139  RGLSHLHQHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPK 198
            +GL +LH+  +IHRD+K  N+L+T+   VK+ DFG++    +        + T ++ AP+
Sbjct: 1016 KGLRYLHEAFIIHRDLKVSNLLMTDKGCVKIADFGLARNYGKPQKPMTPKVVTLWYRAPE 837

Query: 199  SL 200
             L
Sbjct: 836  LL 831
>14116
          Length = 1017

 Score = 61.2 bits (147), Expect = 3e-09,   Method: Composition-based stats.
 Identities = 51/182 (28%), Positives = 85/182 (46%), Gaps = 10/182 (5%)
 Frame = -1

Query: 29  ELVGNGTYGQVYKG----RHVKTGQLAAIKVMDVTGDEEEEIK---QEINMLKKYSHHRN 81
           E +G G +G V +G       K   L A+K +      E E++   QE  ++K + HH N
Sbjct: 618 EEIGKGNFGCVKRGFLTLPEQKGDILVAVKTLHNNNPREIELQSFLQEALIMKDF-HHSN 442

Query: 82  IATYYGAFIKKNPPGMDDQLWLVMEFCGAGSVTDLIKNTKGNTLKEEWIAYICREILRGL 141
           + T  G  +      +DD   +V+ F   G +   I++ +     ++ I Y   +I RG+
Sbjct: 441 VLTLIGICLN-----LDDMPLVVLPFMKHGDLLTYIRDDQHQPTIKDLIMYGV-DIARGM 280

Query: 142 SHLHQHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQL--DRTVGRRNTFIGTPY-WMAPK 198
            +L   K +HRD+  +N +L E+  VK+ DFG++  +         N     P  WMA +
Sbjct: 279 DYLAGLKFVHRDLAARNCMLDEDFHVKVADFGLARDIYEKEYYSSENKKAKLPVKWMALE 100

Query: 199 SL 200
           SL
Sbjct: 99  SL 94
>09606
          Length = 1300

 Score = 60.8 bits (146), Expect = 3e-09,   Method: Composition-based stats.
 Identities = 42/151 (27%), Positives = 71/151 (47%)
 Frame = -3

Query: 25   FELVELVGNGTYGQVYKGRHVKTGQLAAIKVMDVTGDEEEEIKQEINMLKKYSHHRNIAT 84
            F L E +G G +  +YKGR   T    AI  ++    +  E+   + M    SH  N+  
Sbjct: 1109 FVLYEELGKGEHSIIYKGRRKGTINFVAIHCIEKC--KRPEVTNTVRMTHDISH-PNVVQ 939

Query: 85   YYGAFIKKNPPGMDDQLWLVMEFCGAGSVTDLIKNTKGNTLKEEWIAYICREILRGLSHL 144
            ++  +   N       LWLV+E C  GS+ D++   + + L E  I      ++ GL ++
Sbjct: 938  FHEWYETSN------HLWLVVELCTGGSLADIL--AQDHHLPETSIRDFGIHLVTGLHYI 783

Query: 145  HQHKVIHRDIKGQNVLLTENAEVKLVDFGVS 175
            H   ++  D++   VLL  +  +K  DFG+S
Sbjct: 782  HSLGILFHDLRPSKVLLDTSGVLKFADFGLS 690
>27405
          Length = 532

 Score = 60.1 bits (144), Expect = 6e-09,   Method: Composition-based stats.
 Identities = 45/173 (26%), Positives = 84/173 (48%), Gaps = 8/173 (4%)
 Frame = -3

Query: 36  YGQVYKGRHVKTGQLAAIKVMD-----VTGDEEEEIKQEINMLKKYSHHRN---IATYYG 87
           +G+VY  R   TG++ A+K +D     + G E   + + I ML   S       I     
Sbjct: 527 FGEVYGCRKADTGKMYAMKCLDKKRIKMKGGETLALNERI-MLSLVSTGEGSPFIVCMTY 351

Query: 88  AFIKKNPPGMDDQLWLVMEFCGAGSVTDLIKNTKGNTLKEEWIAYICREILRGLSHLHQH 147
           AF  + P    ++L  +++    G +   +  ++     E+ + +   E++ GL H+H  
Sbjct: 350 AF--QTP----EKLCFILDLMNGGDLHYHL--SQHGVFTEKEVRFYAAEVMLGLEHMHSR 195

Query: 148 KVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPKSL 200
            V++RD+K  N+LL EN  V++ D G++    +   + +  +GT  +MAP+ L
Sbjct: 194 FVVYRDLKPANILLDENGHVRISDLGLACDFSKK--KPHASVGTHGYMAPEVL 42
>00392
          Length = 668

 Score = 60.1 bits (144), Expect = 6e-09,   Method: Composition-based stats.
 Identities = 44/142 (30%), Positives = 74/142 (52%), Gaps = 5/142 (3%)
 Frame = +3

Query: 62  EEEEIKQEINMLKKYSHHRNIATYYGAFIKKNPPGMDDQLWLVMEFCGAGSVTDLIKNTK 121
           E +  K+E  MLK+   H NI  ++  + + N       + LV E   +G++   +K  K
Sbjct: 60  ERQRFKEEAEMLKEL-QHPNIVRFFDYWEEHNHRNRK-VIILVTELMTSGTLKTYLKRFK 233

Query: 122 GNTLK--EEWIAYICREILRGLSHLHQHK--VIHRDIKGQNVLLT-ENAEVKLVDFGVSA 176
              +K  + W    CR++L+GL  LH     VIHRD+K  N+ +T     VK+ D G++ 
Sbjct: 234 KPNVKILKNW----CRQVLKGLYFLHTRTPPVIHRDLKCDNIFITGPTGSVKIGDLGLAT 401

Query: 177 QLDRTVGRRNTFIGTPYWMAPK 198
             +++  +  + IGTP +MAP+
Sbjct: 402 LKNQSFAK--SVIGTPEFMAPE 461
>30755
          Length = 1137

 Score = 59.3 bits (142), Expect = 1e-08,   Method: Composition-based stats.
 Identities = 30/75 (40%), Positives = 47/75 (62%), Gaps = 1/75 (1%)
 Frame = +2

Query: 127 EEWIAYICREILRGLSHLHQHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRN 186
           EE   +   EI+  L +LH   +I+RD+K +N+LL ++  +K+ DFG+  + D T GR  
Sbjct: 29  EERTRFYGAEIISALGYLHSQGIIYRDLKLENLLLDKDGHIKVADFGLCKE-DITYGRTT 205

Query: 187 -TFIGTPYWMAPKSL 200
            TF GTP ++AP+ L
Sbjct: 206 KTFCGTPEYLAPEVL 250
>21808
          Length = 1011

 Score = 58.5 bits (140), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 46/190 (24%), Positives = 88/190 (46%), Gaps = 5/190 (2%)
 Frame = +1

Query: 51  AAIKVMDVTGDEEEEIKQEINMLKKYSHHRNIATYYGAFIKKNPPGMDDQLWLVMEFCGA 110
            AIK +     + ++   E  ++KK  H + I  Y            DD ++++ E    
Sbjct: 28  VAIKTLKSGTMDPKDFLAEAQIMKKLRHPKLIQLYAVC-------TQDDPIFIITELMKN 186

Query: 111 GSVTDLIKNTKGNTLKEEWIAYICREILRGLSHLHQHKVIHRDIKGQNVLLTENAEVKLV 170
           GS+ + ++  KG  LK   +  I  +I  G+++L     IHRD+  +N+L+++N  VK+ 
Sbjct: 187 GSLLEFLQG-KGRVLKLPALIDIGAQIACGMAYLESQNYIHRDLAARNILVSDNNTVKIA 363

Query: 171 DFGVS-----AQLDRTVGRRNTFIGTPYWMAPKSLPVMRTRMPHMISRVTCGLWESPPLR 225
           DFG++      + +  VG R        W AP++    R  +   +   + G+  +  + 
Sbjct: 364 DFGLARVIKEDEYEARVGARFPI----KWTAPEAANYNRFTIKSDVW--SFGILLTETVT 525

Query: 226 WQKVPPPSVT 235
           + +VP P +T
Sbjct: 526 YGRVPYPGMT 555
>15910
          Length = 1361

 Score = 52.8 bits (125), Expect(2) = 5e-08,   Method: Composition-based stats.
 Identities = 26/68 (38%), Positives = 48/68 (70%), Gaps = 3/68 (4%)
 Frame = +2

Query: 136 EILRGLSHLHQHKVIHRDIKGQNVL---LTENAEVKLVDFGVSAQLDRTVGRRNTFIGTP 192
           +IL G+ ++H + V+HRD+K +N+L   +T+++++KL DFG+S  ++  V + +T  GTP
Sbjct: 488 DILHGVQYIHANGVVHRDLKPENLLYECMTDDSKLKLADFGLSRIIEPEV-QMSTVCGTP 664

Query: 193 YWMAPKSL 200
            + AP+ L
Sbjct: 665 GYCAPEVL 688

 Score = 23.9 bits (50), Expect(2) = 5e-08,   Method: Compositional matrix adjust.
 Identities = 9/19 (47%), Positives = 12/19 (63%)
 Frame = +3

Query: 215 TCGLWESPPLRWQKVPPPS 233
           TCG+WES P+ +     PS
Sbjct: 717 TCGVWESLPIFYCVAMSPS 773
>12786
          Length = 460

 Score = 55.1 bits (131), Expect(2) = 1e-07,   Method: Composition-based stats.
 Identities = 27/73 (36%), Positives = 46/73 (63%), Gaps = 2/73 (2%)
 Frame = -3

Query: 130 IAYICREILRGLSHLHQHKVIHRDIKGQNVLLTENAEVKLVDFGV--SAQLDRTVGRRNT 187
           I +  RE+LR +  LH   VIH D+K  N +L     +KL+DFG+  + Q D+T   +++
Sbjct: 404 IKFYWREMLRAVKALHNEGVIHSDLKPANFMLVA-GNLKLIDFGIANTLQQDKTSVLKDS 228

Query: 188 FIGTPYWMAPKSL 200
            +GTP +M+P+++
Sbjct: 227 RVGTPSYMSPEAI 189

 Score = 20.4 bits (41), Expect(2) = 1e-07,   Method: Compositional matrix adjust.
 Identities = 10/22 (45%), Positives = 11/22 (50%)
 Frame = -1

Query: 214 VTCGLWESPPLRWQKVPPPSVT 235
           VTCG W +    W    PPS T
Sbjct: 103 VTCGRWAASCTTWCTXGPPSST 38
>26560
          Length = 398

 Score = 55.1 bits (131), Expect = 2e-07,   Method: Composition-based stats.
 Identities = 25/74 (33%), Positives = 44/74 (59%)
 Frame = -1

Query: 127 EEWIAYICREILRGLSHLHQHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRN 186
           E+ + +   E++ GL H+H   V++RD+K  N+LL EN  V++ D G++    +   R +
Sbjct: 359 EKEVRFYAAEVMLGLEHMHSRFVVYRDLKPANILLDENGHVRISDLGLACDFSKK--RPH 186

Query: 187 TFIGTPYWMAPKSL 200
             +GT  +MAP+ L
Sbjct: 185 ASVGTHGYMAPEVL 144
>21079
          Length = 878

 Score = 53.9 bits (128), Expect = 4e-07,   Method: Composition-based stats.
 Identities = 31/98 (31%), Positives = 57/98 (58%), Gaps = 2/98 (2%)
 Frame = +1

Query: 103 LVMEFCGAGSVTDLIKNTKGNTLKEEWIAYICREILRGLSHLHQHKVIHRDIKGQNVL-L 161
           LVMEF GAG + + +       L E    +  R+I  G+ ++H   ++H D+K +NVL +
Sbjct: 55  LVMEFVGAGELFERVIRDD-FVLTERDCVHFVRQICSGVGYMHTQSILHLDLKPENVLCV 231

Query: 162 TENA-EVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPK 198
           ++N+ ++K++DFG+ A+  +         GTP ++AP+
Sbjct: 232 SDNSNQIKIIDFGL-ARFYKPGDSLQVLFGTPEFIAPE 342
>18484
          Length = 635

 Score = 53.1 bits (126), Expect = 8e-07,   Method: Composition-based stats.
 Identities = 27/74 (36%), Positives = 39/74 (52%)
 Frame = +1

Query: 125 LKEEWIAYICREILRGLSHLHQHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGR 184
            KE   A+   EI  GL  LH   +I+RD+K  NV+L     +K+ DFG+  +       
Sbjct: 34  FKEPVAAFYAAEIAVGLFFLHDQGIIYRDLKLDNVMLDSEGHIKIADFGMCKEGMTGDAT 213

Query: 185 RNTFIGTPYWMAPK 198
             TF GTP ++AP+
Sbjct: 214 TRTFCGTPDYIAPE 255
>04591
          Length = 1117

 Score = 52.8 bits (125), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 30/110 (27%), Positives = 57/110 (51%), Gaps = 2/110 (1%)
 Frame = -2

Query: 68   QEINMLKKYSHHRNIATYYGAFIKKNPPG-MDDQLWLVMEFCGAGSVTDLIKNTKGN-TL 125
            +EI +L++  H   +        +  P        +L+ E+C    +  L+ N +   +L
Sbjct: 1074 REIKILQQLEHENVVQLQEICHTQAGPYNRYKSTFYLIFEYCDY-DLAGLLNNLRVKFSL 898

Query: 126  KEEWIAYICREILRGLSHLHQHKVIHRDIKGQNVLLTENAEVKLVDFGVS 175
             ++    +  ++L GL ++H  +++HRDIK  N+LLT +  +KL DFG+S
Sbjct: 897  ADK--KNLMSQLLNGLFYIHTKQILHRDIKAANILLTRDGVLKLADFGLS 754
>13066
          Length = 551

 Score = 52.4 bits (124), Expect = 1e-06,   Method: Composition-based stats.
 Identities = 45/176 (25%), Positives = 84/176 (47%), Gaps = 7/176 (3%)
 Frame = +3

Query: 30  LVGNGTYGQVYKGRHVKTGQLAAIKVMDVTGDE----EEEIKQEINMLKKYSHHRNIATY 85
           +V +GT+   Y GR++K     A K++D         E+   +E+++L K  H   I  +
Sbjct: 12  VVVHGTFNDGY-GRNIKL----ACKIIDKEKAPVDFVEKFFPRELDLLTKLDHPYIIQIH 176

Query: 86  YGAFIKKNPPGMDDQLWLVMEFCGAGSVTDLIKNTKGNTLKEEWIAYICREILRGLSHLH 145
             + +++ P       ++ M F   G +   I+      +KE+       ++   L++LH
Sbjct: 177 --SILQRXPKN-----FIFMRFAERGDLLTYIQEV--GFVKEKQAKIWFYQMTTALNYLH 329

Query: 146 QHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRR---NTFIGTPYWMAPK 198
            + V HRD+K +N+LL+ +  VKL DFG +       G +    T+ G+  + AP+
Sbjct: 330 SYDVAHRDLKCENILLSSHFNVKLADFGFACACITESGEKYMSRTYCGSAAYAAPE 497
>28638
          Length = 1458

 Score = 37.0 bits (84), Expect(2) = 2e-06,   Method: Compositional matrix adjust.
 Identities = 19/57 (33%), Positives = 35/57 (61%), Gaps = 2/57 (3%)
 Frame = -1

Query: 146 QHKVIHRDIKGQNVLLT--ENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPKSL 200
           +  +IH D+K +N+LL   + + +K+VDFG S QL +   R   +I + ++ +P+ L
Sbjct: 777 EMNIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQ---RIYQYIQSRFYRSPEVL 616

 Score = 34.3 bits (77), Expect(2) = 2e-06,   Method: Composition-based stats.
 Identities = 31/122 (25%), Positives = 58/122 (47%), Gaps = 3/122 (2%)
 Frame = -3

Query: 25   FELVELVGNGTYGQVYKGRHVKTGQLAAIKVMDVTGDEEEEIKQEINMLKKYSHHRNIAT 84
            +E+  L+G G++GQV K       +  AIK++        + + E+ +L+  + H     
Sbjct: 1141 YEIDSLIGKGSFGQVVKAYDHGDQEQVAIKIIKNKKPFLNQAQIEVKLLELMNRHDADNX 962

Query: 85   YYGAFIKKNPPGMDDQLWLVMEFCGAGSVTDLIKNTKGNTLKEEWIAYICREILRG---L 141
            YY   +K++     + L LV E   + ++ DL++NT       +  + IC  ++ G   L
Sbjct: 961  YYIVRLKRHFM-FRNHLCLVFELL-SYNLYDLLRNTNFRGGLPQLDS*ICSAVVYGAAVL 788

Query: 142  SH 143
            SH
Sbjct: 787  SH 782
>09007
          Length = 1440

 Score = 51.2 bits (121), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 44/186 (23%), Positives = 83/186 (44%), Gaps = 16/186 (8%)
 Frame = -1

Query: 31  VGNGTYGQVYKGR-HVKTGQLAAIKVMDVTGDEEEEIKQEI---NMLKKYSHHRNIATYY 86
           +G G +G V +     ++G+   + V  ++ D+  +  QE      + +   H NI   Y
Sbjct: 855 LGQGHFGTVRQAIWTAESGEKVQVAVKCLSKDKIHKDGQEFLKETAIMQMLDHENIVRVY 676

Query: 87  GAFIKKNPPGMDDQLWLVMEFCGAGSVTDLIKNTKGNTLKEEWIAYIC---REILRGLSH 143
           G  +     G D  + LV E     S+ + +K        +  +  +C   +++  G+S+
Sbjct: 675 GVVMDN---GAD--IMLVTELAPMRSLLECVKEVSARV--DFSVPRLCDFSQQVCDGMSY 517

Query: 144 LHQHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQL---------DRTVGRRNTFIGTPYW 194
           L   +++HRD+  +N+LL   ++VK+ D GVS  L          +T+  +N       W
Sbjct: 516 LESKRLVHRDLAARNILLFSKSKVKISDVGVSGALGAGKEYYQSQQTIHLQNAVA----W 349

Query: 195 MAPKSL 200
            AP+S 
Sbjct: 348 CAPESF 331
>00715
          Length = 1788

 Score = 51.2 bits (121), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 28/100 (28%), Positives = 50/100 (50%)
 Frame = +1

Query: 79  HRNIATYYGAFIKKNPPGMDDQLWLVMEFCGAGSVTDLIKNTKGNTLKEEWIAYICREIL 138
           H N+ +  GA    +    +D  WL ME+ G  ++  ++ N     +       +  ++ 
Sbjct: 103 HVNVVSILGA---TSLHRFEDGAWLAMEYVGPLNLQTIL-NDHQQDIDSSMRLSLALQMA 270

Query: 139 RGLSHLHQHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQL 178
           RGL +LH   ++H D+K  N LLT + ++++ DFG   QL
Sbjct: 271 RGLHYLHSINIVHLDLKPANCLLTRDLKLRIADFGCCHQL 390
>14477
          Length = 493

 Score = 50.8 bits (120), Expect = 3e-06,   Method: Composition-based stats.
 Identities = 45/182 (24%), Positives = 80/182 (43%), Gaps = 13/182 (7%)
 Frame = -1

Query: 31  VGNGTYGQVYKG------RHVKTGQLAAIKVMDVTGDEEEEIKQEINMLKKYSHH---RN 81
           +G G +G V KG      R +    +  +K  D+    + E+ +E  ++KK  H    R 
Sbjct: 466 LGAGNFGSVMKGVCRLDDREIPVA-IKVLKNADLDPSVQSELIKEAEVMKKMDHMHIVRL 290

Query: 82  IATYYGAFIKKNPPGMDDQLWLVMEFCGAGSVTDLIKNTKG----NTLKEEWIAYICREI 137
           I    G           + + LV+E    G +   +   K     N L+  W      ++
Sbjct: 289 IGLCEG-----------ETMMLVLELAKLGPLNKFLPKNKHLPLWNILELMW------QV 161

Query: 138 LRGLSHLHQHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAP 197
            +G+ +L  +K +HRD+  +N+LL +    K+ DFG+S    +T+ R N      Y+MA 
Sbjct: 160 SQGMEYLEANKFVHRDLAARNILLCDEHFAKISDFGMS----KTLSRENN-----YYMAQ 8

Query: 198 KS 199
           ++
Sbjct: 7   EA 2
>07940
          Length = 1336

 Score = 48.1 bits (113), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 27/76 (35%), Positives = 45/76 (59%), Gaps = 2/76 (2%)
 Frame = -3

Query: 127 EEWIAYICREILRGLSHLHQHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRN 186
           ++ I+Y   ++ RG+ +L   + IHRD+  +NVL+ E   +K+ DFG++  L +    R 
Sbjct: 347 KDLISY-AYQVARGMEYLASKQCIHRDLAARNVLVAEEYVLKIADFGLTRNLQQFDYYRK 171

Query: 187 TFIG-TPY-WMAPKSL 200
           T  G  P  WMAP++L
Sbjct: 170 TTDGRLPVKWMAPEAL 123
>27546
          Length = 426

 Score = 47.8 bits (112), Expect = 3e-05,   Method: Composition-based stats.
 Identities = 27/108 (25%), Positives = 55/108 (50%)
 Frame = -1

Query: 68  QEINMLKKYSHHRNIATYYGAFIKKNPPGMDDQLWLVMEFCGAGSVTDLIKNTKGNTLKE 127
           +E+ +L +  H   I  +  + +++ P     ++++ M +   G +   IK T    + E
Sbjct: 333 RELEILTRLDHPNIIQIH--SILQRGP-----KIFIFMRYAEKGDMLSHIKKT--GPIDE 181

Query: 128 EWIAYICREILRGLSHLHQHKVIHRDIKGQNVLLTENAEVKLVDFGVS 175
                   ++ + L +LH H + HRD+K +N+LL++   VK+ DFG +
Sbjct: 180 AQTKVWFFQMAKALQYLHSHDIAHRDLKCENILLSKRLNVKIADFGFA 37
>07836
          Length = 1478

 Score = 46.2 bits (108), Expect = 1e-04,   Method: Composition-based stats.
 Identities = 45/175 (25%), Positives = 78/175 (44%), Gaps = 19/175 (10%)
 Frame = -1

Query: 48   GQLAAIKVMDVTGD----EEEEIKQEINMLKKYSHHRNIATYYGAFIKKNPPGMDDQLWL 103
            G+  A+K+   T +     E E+ Q + +      H NI  +  A IK    G   QL+L
Sbjct: 1478 GENVAVKIFFTTEEASWFRETELYQTVLL-----RHENILGFIAADIKGT--GSWTQLFL 1320

Query: 104  VMEFCGAGSVTDLIKNTKGNTLKEEWIAYICREILRGLSHLH--------QHKVIHRDIK 155
            + ++   GS+ D + +     L    +  +    + GL+HLH        +  + HRDIK
Sbjct: 1319 ITDYHENGSLHDYLLS---RVLDSSEMLALAHSAICGLAHLHIEIFGTRGKPAIAHRDIK 1149

Query: 156  GQNVLLTENAEVKLVDFGV-------SAQLDRTVGRRNTFIGTPYWMAPKSLPVM 203
             +N+L+ +N    + D G+       S ++D     R    GT  +MAP+ L ++
Sbjct: 1148 SKNILVKKNGTCCIADLGLAVRYISESNEVDVAPNPRQ---GTKRYMAPEVLEML 993
>31885
          Length = 529

 Score = 45.8 bits (107), Expect = 1e-04,   Method: Composition-based stats.
 Identities = 25/67 (37%), Positives = 37/67 (55%)
 Frame = -2

Query: 132 YICREILRGLSHLHQHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGT 191
           Y+C+  L  L +L   K++HRDIK  N+LL E     + DF ++ QL+      +T    
Sbjct: 357 YLCQLALV-LDYLRSQKIVHRDIKPDNILLDEQGHCHVTDFNIATQLEDDELATSTSGTR 181

Query: 192 PYWMAPK 198
           PY MAP+
Sbjct: 180 PY-MAPE 163
>24241
          Length = 413

 Score = 45.1 bits (105), Expect = 2e-04,   Method: Composition-based stats.
 Identities = 27/80 (33%), Positives = 43/80 (53%), Gaps = 3/80 (3%)
 Frame = -2

Query: 31  VGNGTYGQVYKGRHVKTGQLAAIKVMDVTGDEE---EEIKQEINMLKKYSHHRNIATYYG 87
           +G GTYG VYK RH  TG+  A+K + + G E+       +EI ML++  H + +     
Sbjct: 319 IGEGTYGVVYKCRHRATGRKLAMKKIRLRGSEDGVPSSAIREIAMLRELRHTQXLVCLED 140

Query: 88  AFIKKNPPGMDDQLWLVMEF 107
             ++      D++L+LV EF
Sbjct: 139 VIME------DERLFLVFEF 98
>07291
          Length = 833

 Score = 44.7 bits (104), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 16/44 (36%), Positives = 32/44 (72%)
 Frame = +1

Query: 135 REILRGLSHLHQHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQL 178
           R+I  G+++L + KV+HR++  +N ++TE+  ++L D+GV+  L
Sbjct: 70  RQIADGMAYLQEVKVVHRNLAARNCIVTEDGRLQLSDYGVTGSL 201
>19761
          Length = 473

 Score = 44.7 bits (104), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 20/62 (32%), Positives = 39/62 (62%), Gaps = 2/62 (3%)
 Frame = -3

Query: 141 LSHLHQHK--VIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPK 198
           L+++H H   ++HRD+K QN+ +TE  +V+L D G++ +L        + +GT  +++P+
Sbjct: 384 LNYMHTHTPVILHRDLKPQNIYVTEKGDVRLGDLGLARKLTGPADFATSQVGTIMYLSPE 205

Query: 199 SL 200
            L
Sbjct: 204 IL 199
>26711
          Length = 405

 Score = 44.7 bits (104), Expect = 3e-04,   Method: Composition-based stats.
 Identities = 25/74 (33%), Positives = 46/74 (62%), Gaps = 4/74 (5%)
 Frame = -2

Query: 133 ICREILRGLSHLHQHKVIHRDIKGQNVLLTENA--EVKLVDFGVSAQLDRTVGRRNTFI- 189
           + +++L  L H+H   V+H D+K  N+LL+ +    V+L+DFG++ +L      + TF+ 
Sbjct: 401 VVKQVLDILQHVHAQGVVHMDLKPSNLLLSGDKLDSVQLIDFGLARKL---YPPQETFLN 231

Query: 190 -GTPYWMAPKSLPV 202
            GTP + +P++L V
Sbjct: 230 HGTPGFTSPEALDV 189
>04138
          Length = 800

 Score = 44.3 bits (103), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 17/43 (39%), Positives = 30/43 (69%)
 Frame = +1

Query: 133 ICREILRGLSHLHQHKVIHRDIKGQNVLLTENAEVKLVDFGVS 175
           IC      L ++H++K++HRD+K  N+L+T+   +KL DFG++
Sbjct: 28  IC*AADERLYYIHRNKILHRDMKAANILITKQGVLKLADFGLA 156
>31489
          Length = 329

 Score = 42.0 bits (97), Expect = 0.002,   Method: Composition-based stats.
 Identities = 18/36 (50%), Positives = 24/36 (66%)
 Frame = +3

Query: 125 LKEEWIAYICREILRGLSHLHQHKVIHRDIKGQNVL 160
           L EE I Y   +ILRGL ++H   V+HRD+K  N+L
Sbjct: 156 LTEEHIRYFLYQILRGLKYIHSANVVHRDLKPSNLL 263
>11404
          Length = 563

 Score = 41.6 bits (96), Expect = 0.002,   Method: Composition-based stats.
 Identities = 34/139 (24%), Positives = 65/139 (46%), Gaps = 2/139 (1%)
 Frame = +1

Query: 25  FELVELVGNGTYGQVYKGRHVKTGQLAAIKVMDVTGDEEEEIKQEINMLKKYSHHRNIAT 84
           +E+  L+G G++GQV K       +  AIK++        + + E+ +L+  + H     
Sbjct: 145 YEIDSLIGKGSFGQVVKAYDHTDNEQVAIKIIKNKKPFLNQAQIEVKLLEMMNRHDTDNK 324

Query: 85  YYGAFIKKNPPGMDDQLWLVMEFCGAGSVTDLIKNTKGNTLKEEWIAYICREILRGLSHL 144
           YY   +K++       L LV E   + ++ DL++NT    +         +++   L  L
Sbjct: 325 YYIVRLKRHFM-FRSHLCLVFELL-SYNLYDLLRNTNFRGVSLNLTRKFAQQLCTALLFL 498

Query: 145 H--QHKVIHRDIKGQNVLL 161
              +  +IH D+K +N+LL
Sbjct: 499 ATPEMSIIHCDLKPENILL 555
>36481
          Length = 806

 Score = 41.6 bits (96), Expect = 0.002,   Method: Composition-based stats.
 Identities = 32/134 (23%), Positives = 63/134 (47%), Gaps = 1/134 (0%)
 Frame = +2

Query: 32  GNGTYGQVYKGRHVKTGQLAAIKVMDVTGDEEEEIKQEINMLKKYSHHRNIATYYGAFIK 91
           G GT+G+V + + +  G   A+K++       E  K EIN+L+K       A +      
Sbjct: 389 GEGTFGKVVQCKDLLKGDDIALKIIKNVDKYREAAKLEINVLEKLREKDPHAKH---MCV 559

Query: 92  KNPPGMDDQLWLVMEFCGAG-SVTDLIKNTKGNTLKEEWIAYICREILRGLSHLHQHKVI 150
           +     D    + + F   G SV D +K+        E + +I  ++   ++ LH++++ 
Sbjct: 560 QMLDWFDYHGHVCISFHMLGLSVFDFLKDNSYGAYPIEQVRHISYQLCYAVNFLHENQLT 739

Query: 151 HRDIKGQNVLLTEN 164
           H D+K +N+L  ++
Sbjct: 740 HTDLKPENILFVDS 781
>28157
          Length = 400

 Score = 41.6 bits (96), Expect = 0.002,   Method: Composition-based stats.
 Identities = 37/125 (29%), Positives = 62/125 (49%), Gaps = 8/125 (6%)
 Frame = +3

Query: 62  EEEEIKQEINMLKKYSHHRNIATYYGAFIKKNPPGMDDQLWLVMEFCGAGSVTDLIKNTK 121
           E++   QE+  L + SH  NI   YGA         D  + LVME+   GS+ +++    
Sbjct: 39  EKKSFMQELKQLSRVSH-PNIVCLYGAC-------RDHPVCLVMEYAEGGSLYNVLH--- 185

Query: 122 GNTLKEEWIAYICREILR----GLSHLHQHK---VIHRDIKGQNVLLTE-NAEVKLVDFG 173
           G+  + ++ A      L     G+ +LH  K   +IHRD+K  N+LL +   ++K+ DFG
Sbjct: 186 GSGPQPQYTAAHAMNWLLQCALGVEYLHGMKPKALIHRDLKPPNLLLIQCGTKLKICDFG 365

Query: 174 VSAQL 178
            +  +
Sbjct: 366 TACDI 380
>01392
          Length = 1806

 Score = 41.2 bits (95), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 28/82 (34%), Positives = 41/82 (50%), Gaps = 8/82 (9%)
 Frame = -1

Query: 125  LKEEWIAYICREILRGLSHLHQHKVIHRDIKGQNVL---LTENAEVKLVDF----GVSAQ 177
            L E   + + R I R L  LH   + HRD+K +N+L   L +   VK+ DF    G+S  
Sbjct: 1800 LCEREASLVVRHIARALDFLHSKGIAHRDLKPENILCEHLDDVVPVKICDFDLASGISCD 1621

Query: 178  LDRT-VGRRNTFIGTPYWMAPK 198
             D T      T +G+  +MAP+
Sbjct: 1620 GDGTKTPELLTPVGSAEYMAPE 1555
>20559
          Length = 430

 Score = 40.4 bits (93), Expect = 0.005,   Method: Composition-based stats.
 Identities = 22/61 (36%), Positives = 38/61 (62%), Gaps = 3/61 (4%)
 Frame = -2

Query: 25  FELVELVGNGTYGQVYKGRHVKTGQLAAIKVMDVTGDEE---EEIKQEINMLKKYSHHRN 81
           +E +E +G GTYG V+K ++ +T ++ A+K + +  D+E       +EI +LK+   HRN
Sbjct: 369 YEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELK-HRN 193

Query: 82  I 82
           I
Sbjct: 192 I 190
>03508
          Length = 1463

 Score = 40.0 bits (92), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 24/93 (25%), Positives = 48/93 (51%), Gaps = 5/93 (5%)
 Frame = +1

Query: 113 VTDLIKNTKGNTLKEEWIAYICR----EILRGLSHLHQHKVIHRDIKGQNVLLT-ENAEV 167
           + + + NT    L + +  Y  R    E+++ L   H   ++HRD+K  NV++  EN ++
Sbjct: 814 IFEHVNNTDFKQLYQTFTDYDIRFYLYELMKALDFCHSMGIMHRDVKPHNVMIDHENKKL 993

Query: 168 KLVDFGVSAQLDRTVGRRNTFIGTPYWMAPKSL 200
           +L+D+G+ A+        N  + + Y+  P+ L
Sbjct: 994 RLIDWGL-AEFYHPGMEYNVRVASRYFKGPELL 1089
>18481
          Length = 437

 Score = 40.0 bits (92), Expect = 0.007,   Method: Composition-based stats.
 Identities = 38/150 (25%), Positives = 68/150 (45%), Gaps = 5/150 (3%)
 Frame = -1

Query: 39  VYKGRHVKTGQLAAIKV--MDVTGDEEEEIKQEINMLKKYSHHRNIATYYGAFIKKNPPG 96
           +Y+G + + G+  A+K+  +DV   + + +  E  + ++   H  + T Y    +K+   
Sbjct: 437 IYQGYNTQDGKDIAVKIEAIDV---KHQLLHYEAKVYEQIGRHPGLPTMYHYGTEKHFNA 267

Query: 97  MDDQLWLVMEFCGAGSVTDLIKNTKGNTLKEEWIAYICREILRGLSHLHQHKVIHRDIKG 156
                 LVME  G       +   +  TLK   I  +  ++L  L  +HQ   IHRD+K 
Sbjct: 266 ------LVMELLGPSLEELFVICKRRFTLKT--ILMVSDQLLSRLEFIHQKCFIHRDLKP 111

Query: 157 QNVLL---TENAEVKLVDFGVSAQLDRTVG 183
            N L+        + ++DFG+S +   T G
Sbjct: 110 DNFLMGLGRHCHRLYIIDFGLSKRYKDTQG 21
>12672
          Length = 773

 Score = 38.9 bits (89), Expect = 0.013,   Method: Composition-based stats.
 Identities = 24/72 (33%), Positives = 39/72 (54%), Gaps = 4/72 (5%)
 Frame = +3

Query: 133 ICREILRGLSHLHQHKVIHRDIKGQNVLLTENAEVKLVDFG--VSAQL--DRTVGRRNTF 188
           I +    G+ +L+ +  +HRDIK  N+LL      K+ DF   VSA     +TV   +  
Sbjct: 6   IVKGTASGIQYLNDNGHVHRDIKTANILLDSEYTAKVGDFATVVSAPSGEGKTVQNASVV 185

Query: 189 IGTPYWMAPKSL 200
           IGT  ++AP+++
Sbjct: 186 IGTAAYLAPEAI 221
>21433
          Length = 590

 Score = 38.1 bits (87), Expect = 0.024,   Method: Compositional matrix adjust.
 Identities = 24/59 (40%), Positives = 34/59 (57%)
 Frame = +2

Query: 140 GLSHLHQHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPK 198
            L + H  KVIHRDIK +N+LL    ++K+ DFG S     +  RR T  GT  ++ P+
Sbjct: 203 ALEYCHYRKVIHRDIKPENLLLGLKGDLKIADFGWSVHAPSS--RRTTMCGTLDYLPPE 373
>25019
          Length = 730

 Score = 37.4 bits (85), Expect = 0.037,   Method: Compositional matrix adjust.
 Identities = 18/44 (40%), Positives = 26/44 (59%)
 Frame = +3

Query: 157 QNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPKSL 200
           +NVLL ++  VKL DFG+  +        +TF GT  +MAP+ L
Sbjct: 261 ENVLLDKDGHVKLTDFGLCKEAITGTRVTHTFCGTIEYMAPEIL 392
>29360
          Length = 363

 Score = 37.0 bits (84), Expect = 0.055,   Method: Composition-based stats.
 Identities = 30/119 (25%), Positives = 55/119 (46%), Gaps = 4/119 (3%)
 Frame = +3

Query: 47  TGQLAAIKVMDVTGDEEEEIKQEINMLKKYSHHR----NIATYYGAFIKKNPPGMDDQLW 102
           T ++ AIK++        + + E+++L++ S       N    +  F  KN         
Sbjct: 24  TSEIVAIKILKNHPSYARQGQIEVSILQRLSQESADDYNFVRAFECFQHKN------HTC 185

Query: 103 LVMEFCGAGSVTDLIKNTKGNTLKEEWIAYICREILRGLSHLHQHKVIHRDIKGQNVLL 161
           LV E     ++ D +K  K   L  ++I  I +++L  L  L Q  +IH D+K +N++L
Sbjct: 186 LVFEML-EQNLYDFLKQNKFQPLPLKYIRPITQQVLTALRKLKQLGLIHADLKPENIML 359
>28865
          Length = 342

 Score = 36.2 bits (82), Expect = 0.097,   Method: Composition-based stats.
 Identities = 26/76 (34%), Positives = 44/76 (57%), Gaps = 3/76 (3%)
 Frame = -3

Query: 4   DSPARSLDEIDLSALRDPAGIFELVELVGNGTYGQVYKGRHVKTGQLAAIKVMD---VTG 60
           D+PA    ++D+S L     IF   +++G+G +G VY G H +T +  AIKV+D      
Sbjct: 241 DTPADK--QVDISQLYQ---IFP-EDVLGSGQFGIVYGGCHRRTNREVAIKVIDKLRFPT 80

Query: 61  DEEEEIKQEINMLKKY 76
            +E ++K E+ +L+ Y
Sbjct: 79  KQEAQLKTEVAILQNY 32
>32359
          Length = 928

 Score = 34.3 bits (77), Expect = 0.33,   Method: Composition-based stats.
 Identities = 33/140 (23%), Positives = 66/140 (47%), Gaps = 2/140 (1%)
 Frame = -1

Query: 29  ELVGNGTYGQVYKGRHVKTGQLAAIKVMDVTGDEEEEIKQEINMLKKYSHHRNIATYYGA 88
           +++GNG++G VY+ + V T +L AIK   V  D+  +  +E+ +++K   H+NI      
Sbjct: 412 KVIGNGSFGVVYQAKLVDTSELVAIK--KVLQDKRFK-NRELQIMRKL-EHQNIVKLKFF 245

Query: 89  FIKKNPPGMDDQLWLVMEFCGAGSVTDLIK--NTKGNTLKEEWIAYICREILRGLSHLHQ 146
           F        +  L LV+E+    +V  + +  +    T+   +I     ++ R L+++H 
Sbjct: 244 FYSSGEKKDEVFLNLVLEYV-PETVYRVARHYSKSKQTIPILYIKLYMYQLFRSLAYIHS 68

Query: 147 HKVIHRDIKGQNVLLTENAE 166
              +      +   LT+  E
Sbjct: 67  QACVTATSSLKTCCLTQRLE 8
>17300
          Length = 480

 Score = 34.3 bits (77), Expect = 0.37,   Method: Composition-based stats.
 Identities = 22/68 (32%), Positives = 35/68 (51%), Gaps = 4/68 (5%)
 Frame = +1

Query: 137 ILRGLSHLHQHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQL--DRTVGRRNTFIGT--P 192
           I  G+  L     +HRD+  +N+L+ E    K+ DFG+S ++  D T G   T  G    
Sbjct: 1   ISSGMGXLADMGYVHRDLAARNILVNEILVCKVADFGLSREIESDTTEGAYTTKGGKIPV 180

Query: 193 YWMAPKSL 200
            W AP+++
Sbjct: 181 RWTAPEAI 204
>01106
          Length = 878

 Score = 33.5 bits (75), Expect = 0.58,   Method: Composition-based stats.
 Identities = 14/33 (42%), Positives = 24/33 (72%), Gaps = 1/33 (3%)
 Frame = +3

Query: 130 IAYICREILRGLSHLHQH-KVIHRDIKGQNVLL 161
           +  I R++L GLS++H   ++IH DIK +N+L+
Sbjct: 651 VKLIIRQVLEGLSYMHAKCRIIHTDIKPENILI 749
>21800
          Length = 855

 Score = 33.1 bits (74), Expect = 0.75,   Method: Composition-based stats.
 Identities = 14/33 (42%), Positives = 23/33 (69%), Gaps = 1/33 (3%)
 Frame = +2

Query: 130 IAYICREILRGLSHLHQH-KVIHRDIKGQNVLL 161
           +  I R++L GL++LH    +IH DIK +N+L+
Sbjct: 638 VKLIIRQVLEGLNYLHAKCNIIHTDIKPENILI 736
>15741
          Length = 402

 Score = 32.7 bits (73), Expect = 0.97,   Method: Composition-based stats.
 Identities = 10/24 (41%), Positives = 19/24 (79%)
 Frame = -3

Query: 137 ILRGLSHLHQHKVIHRDIKGQNVL 160
           + RG++H+  +K++HRD+  +NVL
Sbjct: 73  VARGMAHVANNKIVHRDVAARNVL 2
>26009
          Length = 886

 Score = 32.3 bits (72), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 10/29 (34%), Positives = 21/29 (72%)
 Frame = +3

Query: 133 ICREILRGLSHLHQHKVIHRDIKGQNVLL 161
           + ++++  L  +H  +++HRDIK +NVL+
Sbjct: 726 VMKQLVSALDFMHSKQLVHRDIKPENVLI 812
>02717
          Length = 862

 Score = 30.4 bits (67), Expect = 5.0,   Method: Compositional matrix adjust.
 Identities = 21/49 (42%), Positives = 28/49 (57%), Gaps = 2/49 (4%)
 Frame = +1

Query: 990  MKRMMSLQLLPCLLANFLGKN--RPNSMKRGRFQWXMXTQQTFALIVTH 1036
            +K+M S QL  C+ +N  GKN  R NSMK G+F W +     F L  +H
Sbjct: 277  VKKMKSSQL--CVSSN--GKNGCRQNSMKLGKFLWPLEVSTNFLL*KSH 411
>11185
          Length = 473

 Score = 29.6 bits (65), Expect = 8.9,   Method: Composition-based stats.
 Identities = 12/39 (30%), Positives = 23/39 (58%)
 Frame = +1

Query: 137 ILRGLSHLHQHKVIHRDIKGQNVLLTENAEVKLVDFGVS 175
           ++ GL ++H   ++  D++   VLL  +  +K  DFG+S
Sbjct: 28  LVTGLHYIHSLGILFHDLRPSKVLLDTSGVLKFADFGLS 144
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|38259194|ref|NP_940804.1| DnaJ (Hsp40) homolog,
subfamily C, member 6 [Mus musculus]
         (900 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

33510                                                                 158   8e-39
13998                                                                  37   0.031
14550                                                                  35   0.17 
02088                                                                  35   0.18 
13422                                                                  33   0.68 
05775                                                                  32   0.81 
27662                                                                  32   1.3  
26984                                                                  30   3.1  
>33510
          Length = 501

 Score =  158 bits (400), Expect = 8e-39,   Method: Composition-based stats.
 Identities = 74/138 (53%), Positives = 95/138 (68%)
 Frame = +3

Query: 763 KQKAADFEDLLSSQGFNAHKDKKGPRTIXXXXXXXXXXXXDPEKLKILEWIEGKERNIRA 822
           K  A  FEDLL    F++   K  P+TI            DP+KLK++EW +GKE+NIRA
Sbjct: 39  KVSANQFEDLLGEANFSSASKKDEPKTIADMRRKQLEEDMDPDKLKVMEWTQGKEKNIRA 218

Query: 823 LLSTMHTVLWAGETKWKPVGMADLVTPEQVKKVYRRAVLVVHPDKATGQPYEQYAKMIFM 882
           LL ++  VLW  E++WKP GM DLV+ +QVKKVYR+AVL VHPDK    P+E  AK+IFM
Sbjct: 219 LLCSLDKVLWDSESRWKPCGMHDLVSADQVKKVYRKAVLSVHPDKLHDDPHEALAKLIFM 398

Query: 883 ELNDAWSEFENQGQKPLY 900
           ELNDAW++FE++G K LY
Sbjct: 399 ELNDAWAKFEDEGMKSLY 452
>13998
          Length = 1075

 Score = 37.4 bits (85), Expect = 0.031,   Method: Compositional matrix adjust.
 Identities = 22/85 (25%), Positives = 43/85 (50%), Gaps = 4/85 (4%)
 Frame = +1

Query: 820 IRALLSTMHTVLWAGETK--WKPVGMADLVTPEQVKKVYRRAVLVVHPDKATGQPYE--Q 875
           I+ LL      L   + K  +K +G++   T +++KK YR+  LV HPD+      +  +
Sbjct: 151 IKRLLRDAKFALKKSKRKDYYKILGISRNATEDEIKKAYRKKALVHHPDRHANSSADVRK 330

Query: 876 YAKMIFMELNDAWSEFENQGQKPLY 900
             ++ F E+ +A++   +  +K  Y
Sbjct: 331 DEELKFKEVGEAYAILSDGAKKTRY 405
>14550
          Length = 1395

 Score = 34.7 bits (78), Expect = 0.17,   Method: Compositional matrix adjust.
 Identities = 18/77 (23%), Positives = 37/77 (48%)
 Frame = -1

Query: 824  LSTMHTVLWAGETKWKPVGMADLVTPEQVKKVYRRAVLVVHPDKATGQPYEQYAKMIFME 883
            L  +   +  G   +K +G++     +Q+K+ YR+    +HPDK    P    A+  F +
Sbjct: 1170 LLLLFVQVLGGRDFYKILGVSKSADTKQIKRAYRKIAKELHPDKNRDDP---EAEQRFQD 1000

Query: 884  LNDAWSEFENQGQKPLY 900
            L  A+    ++ ++ +Y
Sbjct: 999  LGAAYEVLSDEEKRKVY 949
>02088
          Length = 1062

 Score = 34.7 bits (78), Expect = 0.18,   Method: Composition-based stats.
 Identities = 22/85 (25%), Positives = 42/85 (49%)
 Frame = +3

Query: 816 KERNIRALLSTMHTVLWAGETKWKPVGMADLVTPEQVKKVYRRAVLVVHPDKATGQPYEQ 875
           K+ ++ ALL +    L+     ++ +G+    TP++VKK Y +  L VHPD+ +    E 
Sbjct: 51  KKEDLPALLQSCEE-LFETTDLYEVIGIRREATPQEVKKGYHKVSLAVHPDQVSAAEKET 227

Query: 876 YAKMIFMELNDAWSEFENQGQKPLY 900
            A   F  L   ++   ++ ++  Y
Sbjct: 228 -ATRKFQTLGKVYTVLSDKDKRAXY 299
>13422
          Length = 930

 Score = 32.7 bits (73), Expect = 0.68,   Method: Compositional matrix adjust.
 Identities = 15/52 (28%), Positives = 29/52 (55%), Gaps = 3/52 (5%)
 Frame = +1

Query: 823 LLSTMHTVLWAGETKWKPVGMADL---VTPEQVKKVYRRAVLVVHPDKATGQ 871
           LL  ++   W  +  +  +G++ L    T + +K++YR+ VL+ HPDK   +
Sbjct: 298 LLLGLNPKEWKKQDHYAVLGLSKLRYKATADHIKRIYRQKVLLHHPDKRRAR 453
>05775
          Length = 1303

 Score = 32.3 bits (72), Expect = 0.81,   Method: Compositional matrix adjust.
 Identities = 15/27 (55%), Positives = 18/27 (66%)
 Frame = +2

Query: 553 SASASPTLRVGEGATFDPFGAPAKPPG 579
           S+S+SP   VG+G TFD  G   KPPG
Sbjct: 272 SSSSSPVALVGKGITFDTGGISLKPPG 352
>27662
          Length = 976

 Score = 31.6 bits (70), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 19/56 (33%), Positives = 30/56 (53%)
 Frame = +2

Query: 277 ITVQGDVIVSMYHLRSTIGSRLQAKVTNTQIFQLQFHSGFIPLDTTVLKFTKPELD 332
           I ++GD+++  YH ++  G R         I+Q QFH+  I  +  V  F+K ELD
Sbjct: 2   IPLRGDILIKCYHKKARSGQR-------EVIWQCQFHTCAIQDNNVV--FSKHELD 142
>26984
          Length = 1107

 Score = 30.4 bits (67), Expect = 3.1,   Method: Compositional matrix adjust.
 Identities = 12/34 (35%), Positives = 21/34 (61%)
 Frame = -2

Query: 834 GETKWKPVGMADLVTPEQVKKVYRRAVLVVHPDK 867
           G+  +  +G+    + E +K+ YRR  ++VHPDK
Sbjct: 521 GKDPYSILGLRADASDEDIKRYYRRQAVLVHPDK 420
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|46560563|ref|NP_035495.2| SH3 domain protein 1B [Mus
musculus]
         (1658 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

20131                                                                 158   1e-38
30482                                                                  77   9e-14
12324                                                                  70   8e-12
01130                                                                  62   2e-09
16716                                                                  58   3e-08
19303                                                                  57   6e-08
36305                                                                  56   1e-07
01494                                                                  52   3e-06
17286                                                                  50   6e-06
29687                                                                  50   1e-05
26032                                                                  47   7e-05
32146                                                                  45   2e-04
13664                                                                  45   3e-04
28095                                                                  44   5e-04
11641                                                                  44   7e-04
14539                                                                  42   0.001
18372                                                                  42   0.002
17768                                                                  41   0.004
33143                                                                  40   0.010
19469                                                                  40   0.011
05237                                                                  39   0.012
15115                                                                  39   0.012
14594                                                                  39   0.014
18050                                                                  39   0.016
29243                                                                  39   0.019
36643                                                                  39   0.022
21187                                                                  39   0.022
38272                                                                  38   0.032
31183                                                                  37   0.062
27252                                                                  37   0.088
01019                                                                  37   0.089
30740                                                                  36   0.11 
19562                                                                  36   0.11 
14366                                                                  34   0.60 
39077                                                                  33   0.87 
05206                                                                  33   1.3  
29179                                                                  32   1.9  
07385                                                                  32   2.3  
18881                                                                  31   3.5  
32088                                                                  31   4.3  
22144                                                                  31   5.0  
01678                                                                  30   5.8  
01124                                                                  30   6.1  
>20131
          Length = 574

 Score =  158 bits (400), Expect = 1e-38,   Method: Compositional matrix adjust.
 Identities = 79/142 (55%), Positives = 102/142 (71%)
 Frame = -2

Query: 944  GEDYIALYSYSSVEPGDLTFTEGEEILVTQKDGEWWTGSIGERTGIFPSNYVRPKDQENF 1003
            GE Y+A+YSY S E  DLTF EG+ ILVT+KD +WWTG++GE+TG+FPS YV+ K +   
Sbjct: 483  GEYYVAMYSYVSGETADLTFNEGDMILVTKKDEDWWTGTLGEKTGMFPSTYVK-KVEIQP 307

Query: 1004 GNASKSGASNKKPEIAQVTSAYAASGTEQLSLAPGQLILILKKNTSGWWQGELQARGKKR 1063
            G  S      KKPEIA V + Y A+G  QLSL PG LI + +K+  GWW+GELQARG+++
Sbjct: 306  GQKSA-----KKPEIAMVIAPYTATGNGQLSLEPGNLIHVRQKSPRGWWEGELQARGQRK 142

Query: 1064 QKGWFPASHVKLLGPSSERTMP 1085
            + GWFPA +VK LG SS R+ P
Sbjct: 141  KIGWFPADYVKPLGSSSARSTP 76

 Score = 58.2 bits (139), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 49/167 (29%), Positives = 76/167 (45%), Gaps = 6/167 (3%)
 Frame = -2

Query: 859  ALCSWTAKKENHLNFSKHDVITVLEQQENWWFGEVHGGRGWFPKSYVKLIPGNEVQRGEP 918
            A+ S+ + +   L F++ D+I V ++ E+WW G +    G FP +YVK +   E+Q G+ 
Sbjct: 468  AMYSYVSGETADLTFNEGDMILVTKKDEDWWTGTLGEKTGMFPSTYVKKV---EIQPGQK 298

Query: 919  EALYAAVTKKPTSTAYPVTSTAYPVGEDYIALYSYSSVEPGDLTFTEGEEILVTQKDGE- 977
             A      KKP               E  + +  Y++   G L+   G  I V QK    
Sbjct: 297  SA------KKP---------------EIAMVIAPYTATGNGQLSLEPGNLIHVRQKSPRG 181

Query: 978  WWTGSI---GER--TGIFPSNYVRPKDQENFGNASKSGASNKKPEIA 1019
            WW G +   G+R   G FP++YV+P         S S  S   P++A
Sbjct: 180  WWEGELQARGQRKKIGWFPADYVKPL-------GSSSARSTPDPKVA 61

 Score = 56.2 bits (134), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 40/125 (32%), Positives = 59/125 (47%), Gaps = 5/125 (4%)
 Frame = -2

Query: 1024 AYAASGTEQLSLAPGQLILILKKNTSGWWQGELQARGKKRQKGWFPASHVKLLGPSSERT 1083
            +Y +  T  L+   G +IL+ KK+   WW G L   G+K   G FP+++VK +     + 
Sbjct: 459  SYVSGETADLTFNEGDMILVTKKDED-WWTGTL---GEK--TGMFPSTYVKKVEIQPGQK 298

Query: 1084 MPTFHAVCQVIAMYDYMANNEDELNFSKGQLINVMNKDDPDWWQGETNGL-----TGLFP 1138
                  +  VIA Y    N +  L+   G LI+V  K    WW+GE          G FP
Sbjct: 297  SAKKPEIAMVIAPYTATGNGQ--LSLEPGNLIHVRQKSPRGWWEGELQARGQRKKIGWFP 124

Query: 1139 SNYVK 1143
            ++YVK
Sbjct: 123  ADYVK 109

 Score = 53.5 bits (127), Expect = 6e-07,   Method: Compositional matrix adjust.
 Identities = 23/50 (46%), Positives = 32/50 (64%)
 Frame = -2

Query: 1094 IAMYDYMANNEDELNFSKGQLINVMNKDDPDWWQGETNGLTGLFPSNYVK 1143
            +AMY Y++    +L F++G +I V  KD+ DWW G     TG+FPS YVK
Sbjct: 471  VAMYSYVSGETADLTFNEGDMILVTKKDE-DWWTGTLGEKTGMFPSTYVK 325

 Score = 40.8 bits (94), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 27/73 (36%), Positives = 37/73 (50%), Gaps = 8/73 (10%)
 Frame = -2

Query: 726 LYPFEARNHDEMSFSSGDIIQVDEKTVGEPGWLYGSFQG-----KFGWFPCNYVEKVLSS 780
           + P+ A  + ++S   G++I V +K+    GW  G  Q      K GWFP +YV K L S
Sbjct: 267 IAPYTATGNGQLSLEPGNLIHVRQKS--PRGWWEGELQARGQRKKIGWFPADYV-KPLGS 97

Query: 781 EKALS---PKKAL 790
             A S   PK AL
Sbjct: 96  SSARSTPDPKVAL 58

 Score = 37.4 bits (85), Expect = 0.045,   Method: Compositional matrix adjust.
 Identities = 19/55 (34%), Positives = 31/55 (56%)
 Frame = -2

Query: 723 YRALYPFEARNHDEMSFSSGDIIQVDEKTVGEPGWLYGSFQGKFGWFPCNYVEKV 777
           Y A+Y + +    +++F+ GD+I V +K   +  W  G+   K G FP  YV+KV
Sbjct: 474 YVAMYSYVSGETADLTFNEGDMILVTKK---DEDWWTGTLGEKTGMFPSTYVKKV 319
>30482
          Length = 610

 Score = 76.6 bits (187), Expect = 9e-14,   Method: Compositional matrix adjust.
 Identities = 57/170 (33%), Positives = 85/170 (50%), Gaps = 6/170 (3%)
 Frame = +3

Query: 723 YRALYPFEARNHDEMSFSSGDIIQVDEKTVGEPG---WLYGSFQ-GKFGWFPCNYVEKVL 778
           YRAL+PFE+R+ DE++ ++GD I V +    EPG   W  G  + GK GWFP  Y E   
Sbjct: 129 YRALFPFESRSEDELNINTGDDIWVWD-VPSEPGMEEWFKGETKDGKVGWFPQAYAEP-- 299

Query: 779 SSEKALSPKKALXXXXXXXXXXXXXXXXXXXXXDYHNVSFS-NLTVNTTWQQKSAFTRTV 837
                 +P+ A                         NV+ + +  V  ++   SA    +
Sbjct: 300 ------NPEPAAPAFSSQPASSDVFGSAFQPVQQSANVASAFSAGVADSFNTPSA--PPI 455

Query: 838 SPGSVSPIHGQG-QAVENLKAQALCSWTAKKENHLNFSKHDVITVLEQQE 886
           +  S  P  G+  +A E LKAQAL  W A+++NHL+F+K D+I V EQ++
Sbjct: 456 AESSFQPTPGESHKAPEGLKAQALYQWKARQDNHLSFNKDDIIVVKEQED 605

 Score = 38.5 bits (88), Expect = 0.023,   Method: Compositional matrix adjust.
 Identities = 23/76 (30%), Positives = 39/76 (51%), Gaps = 6/76 (7%)
 Frame = +3

Query: 840 GSVSPIHGQGQAVENLKAQALCSWTAKKENHLNFSKHDVITVLE-----QQENWWFGEVH 894
           G+  P  G G  ++  + +AL  + ++ E+ LN +  D I V +       E W+ GE  
Sbjct: 81  GTTDPFAG-GSGIKKTRYRALFPFESRSEDELNINTGDDIWVWDVPSEPGMEEWFKGETK 257

Query: 895 GGR-GWFPKSYVKLIP 909
            G+ GWFP++Y +  P
Sbjct: 258 DGKVGWFPQAYAEPNP 305
>12324
          Length = 946

 Score = 70.1 bits (170), Expect = 8e-12,   Method: Composition-based stats.
 Identities = 34/76 (44%), Positives = 51/76 (67%)
 Frame = +3

Query: 1068 FPASHVKLLGPSSERTMPTFHAVCQVIAMYDYMANNEDELNFSKGQLINVMNKDDPDWWQ 1127
            + A+    LGP  +  MP  + + +V+A+YDY A  +DEL FS+  +I V+ K+D  WW+
Sbjct: 630  YAATGPGFLGP--DEYMPATY-IEKVVAIYDYEAEKDDELTFSENSVIYVIRKNDDGWWE 800

Query: 1128 GETNGLTGLFPSNYVK 1143
            G  +G+TGLFPSNYV+
Sbjct: 801  GVMDGVTGLFPSNYVE 848

 Score = 50.4 bits (119), Expect = 6e-06,   Method: Composition-based stats.
 Identities = 24/54 (44%), Positives = 33/54 (61%), Gaps = 1/54 (1%)
 Frame = +3

Query: 945 EDYIALYSYSSVEPGDLTFTEGEEILVTQK-DGEWWTGSIGERTGIFPSNYVRP 997
           E  +A+Y Y + +  +LTF+E   I V +K D  WW G +   TG+FPSNYV P
Sbjct: 690 EKVVAIYDYEAEKDDELTFSENSVIYVIRKNDDGWWEGVMDGVTGLFPSNYVEP 851

 Score = 43.5 bits (101), Expect = 7e-04,   Method: Composition-based stats.
 Identities = 22/54 (40%), Positives = 29/54 (53%)
 Frame = +3

Query: 725 ALYPFEARNHDEMSFSSGDIIQVDEKTVGEPGWLYGSFQGKFGWFPCNYVEKVL 778
           A+Y +EA   DE++FS   +I V  K   + GW  G   G  G FP NYVE  +
Sbjct: 702 AIYDYEAEKDDELTFSENSVIYVIRKN--DDGWWEGVMDGVTGLFPSNYVEPCM 857

 Score = 40.0 bits (92), Expect = 0.009,   Method: Composition-based stats.
 Identities = 19/52 (36%), Positives = 33/52 (63%), Gaps = 1/52 (1%)
 Frame = +3

Query: 856 KAQALCSWTAKKENHLNFSKHDVITVLEQQEN-WWFGEVHGGRGWFPKSYVK 906
           K  A+  + A+K++ L FS++ VI V+ + ++ WW G + G  G FP +YV+
Sbjct: 693 KVVAIYDYEAEKDDELTFSENSVIYVIRKNDDGWWEGVMDGVTGLFPSNYVE 848

 Score = 34.7 bits (78), Expect = 0.32,   Method: Composition-based stats.
 Identities = 14/50 (28%), Positives = 28/50 (56%)
 Frame = +3

Query: 1025 YAASGTEQLSLAPGQLILILKKNTSGWWQGELQARGKKRQKGWFPASHVK 1074
            Y A   ++L+ +   +I +++KN  GWW+G +         G FP+++V+
Sbjct: 714  YEAEKDDELTFSENSVIYVIRKNDDGWWEGVMDG-----VTGLFPSNYVE 848
>01130
          Length = 1032

 Score = 62.0 bits (149), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 35/98 (35%), Positives = 51/98 (52%), Gaps = 1/98 (1%)
 Frame = +3

Query: 16  WAITS-EERTKHDKQFDNLKPSGGYITGDQARTFFLQSGLPAPVLAEIWALSDLNKDGKM 74
           W + S EER  ++  F +  P  GYI G+  R  FL+SGL   VL++IW L+D++ D  +
Sbjct: 210 WPVVSDEERQLYELLFYSQGPVDGYILGEGVRDLFLKSGLSLRVLSQIWNLADVSNDNVL 389

Query: 75  DQQEFSIAMXXXXXXXXXXXXPVVLPPIMKQPPMFSPL 112
           +  EFS+ M            P  LP  +  PP  +PL
Sbjct: 390 NVHEFSLVMHLIRGLHKGLKAPPTLPRKLT-PPKTAPL 500

 Score = 58.5 bits (140), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 28/77 (36%), Positives = 41/77 (53%)
 Frame = +3

Query: 240 AVPQPSRLKYRQKFNSLDKGMSGYLSGFQARNALLQSNLSQTQLATIWTLADIDGDGQLK 299
           A+  P R  Y + F +LD    G+L G   R+    S L+   L+ +W L+D+  DG+L 
Sbjct: 510 AITPPEREAYIKLFRALDVQGKGFLDGDCCRHVFEASELTSDVLSDVWNLSDVTRDGKLD 689

Query: 300 AEEFILAMHLTDMAKAG 316
            +EF +A HL    KAG
Sbjct: 690 VDEFCVACHLLRFVKAG 740

 Score = 56.6 bits (135), Expect = 8e-08,   Method: Compositional matrix adjust.
 Identities = 29/67 (43%), Positives = 40/67 (59%), Gaps = 1/67 (1%)
 Frame = +3

Query: 17  AITSEERTKHDKQFDNLKPSG-GYITGDQARTFFLQSGLPAPVLAEIWALSDLNKDGKMD 75
           AIT  ER  + K F  L   G G++ GD  R  F  S L + VL+++W LSD+ +DGK+D
Sbjct: 510 AITPPEREAYIKLFRALDVQGKGFLDGDCCRHVFEASELTSDVLSDVWNLSDVTRDGKLD 689

Query: 76  QQEFSIA 82
             EF +A
Sbjct: 690 VDEFCVA 710

 Score = 47.4 bits (111), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 22/50 (44%), Positives = 28/50 (56%)
 Frame = +3

Query: 260 MSGYLSGFQARNALLQSNLSQTQLATIWTLADIDGDGQLKAEEFILAMHL 309
           + GY+ G   R+  L+S LS   L+ IW LAD+  D  L   EF L MHL
Sbjct: 273 VDGYILGEGVRDLFLKSGLSLRVLSQIWNLADVSNDNVLNVHEFSLVMHL 422
>16716
          Length = 934

 Score = 58.2 bits (139), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 23/52 (44%), Positives = 33/52 (63%)
 Frame = -1

Query: 1093 VIAMYDYMANNEDELNFSKGQLINVMNKDDPDWWQGETNGLTGLFPSNYVKM 1144
             IA+YDY A ++DEL F    +I  +   D  WW+G  +G  GLFP+NYV++
Sbjct: 463  AIALYDYQAADDDELTFDPDDVITDIEMIDDGWWRGSCHGKNGLFPANYVEL 308

 Score = 47.4 bits (111), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 23/51 (45%), Positives = 32/51 (62%)
 Frame = -1

Query: 725 ALYPFEARNHDEMSFSSGDIIQVDEKTVGEPGWLYGSFQGKFGWFPCNYVE 775
           ALY ++A + DE++F   D+I  D + + + GW  GS  GK G FP NYVE
Sbjct: 457 ALYDYQAADDDELTFDPDDVI-TDIEMIDD-GWWRGSCHGKNGLFPANYVE 311

 Score = 46.6 bits (109), Expect = 9e-05,   Method: Compositional matrix adjust.
 Identities = 21/50 (42%), Positives = 28/50 (56%), Gaps = 1/50 (2%)
 Frame = -1

Query: 859 ALCSWTAKKENHLNFSKHDVITVLEQ-QENWWFGEVHGGRGWFPKSYVKL 907
           AL  + A  ++ L F   DVIT +E   + WW G  HG  G FP +YV+L
Sbjct: 457 ALYDYQAADDDELTFDPDDVITDIEMIDDGWWRGSCHGKNGLFPANYVEL 308

 Score = 44.3 bits (103), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 21/53 (39%), Positives = 29/53 (54%), Gaps = 1/53 (1%)
 Frame = -1

Query: 944 GEDYIALYSYSSVEPGDLTFTEGEEIL-VTQKDGEWWTGSIGERTGIFPSNYV 995
           G   IALY Y + +  +LTF   + I  +   D  WW GS   + G+FP+NYV
Sbjct: 472 GSTAIALYDYQAADDDELTFDPDDVITDIEMIDDGWWRGSCHGKNGLFPANYV 314

 Score = 34.7 bits (78), Expect = 0.30,   Method: Compositional matrix adjust.
 Identities = 15/51 (29%), Positives = 27/51 (52%)
 Frame = -1

Query: 1025 YAASGTEQLSLAPGQLILILKKNTSGWWQGELQARGKKRQKGWFPASHVKL 1075
            Y A+  ++L+  P  +I  ++    GWW+G    +      G FPA++V+L
Sbjct: 445  YQAADDDELTFDPDDVITDIEMIDDGWWRGSCHGKN-----GLFPANYVEL 308
>19303
          Length = 676

 Score = 57.0 bits (136), Expect = 6e-08,   Method: Composition-based stats.
 Identities = 27/89 (30%), Positives = 48/89 (53%)
 Frame = -1

Query: 18  ITSEERTKHDKQFDNLKPSGGYITGDQARTFFLQSGLPAPVLAEIWALSDLNKDGKMDQQ 77
           + S E+ ++D  F  L P  G ++G  A++  ++S LP  VL+++W L+D++KDG +D  
Sbjct: 412 VVSREKYEYDDSFSKLNPINGKVSGAAAKSEMVKSKLPNSVLSKVWKLADVDKDGMLDAD 233

Query: 78  EFSIAMXXXXXXXXXXXXPVVLPPIMKQP 106
           E+++A             P  LP  +  P
Sbjct: 232 EWALANHLIKIKLEGHDLPSDLPSHLVPP 146

 Score = 53.5 bits (127), Expect = 6e-07,   Method: Composition-based stats.
 Identities = 28/80 (35%), Positives = 48/80 (60%)
 Frame = -1

Query: 238 EWAVPQPSRLKYRQKFNSLDKGMSGYLSGFQARNALLQSNLSQTQLATIWTLADIDGDGQ 297
           EW V +  + +Y   F+ L+  ++G +SG  A++ +++S L  + L+ +W LAD+D DG 
Sbjct: 418 EWVVSR-EKYEYDDSFSKLNP-INGKVSGAAAKSEMVKSKLPNSVLSKVWKLADVDKDGM 245

Query: 298 LKAEEFILAMHLTDMAKAGQ 317
           L A+E+ LA HL  +   G 
Sbjct: 244 LDADEWALANHLIKIKLEGH 185
>36305
          Length = 586

 Score = 56.2 bits (134), Expect = 1e-07,   Method: Composition-based stats.
 Identities = 26/71 (36%), Positives = 45/71 (63%)
 Frame = -1

Query: 1549 GKSNPYCEVSMGSQSYTTRTLQDTLNPKWNFNCQFFIKDLYQDVLCLTMFDRDQFSPDDF 1608
            GKS+PY  V++G+Q++ T+ + DT+ P+WN   +F I +    +L L + D+D  + DD 
Sbjct: 583  GKSDPYTVVTVGAQTFKTKVIDDTVEPRWNEVFEFVIDERDGQILKLNISDKDPGNKDDP 404

Query: 1609 LGRTEVPVAKI 1619
            LG T + ++ I
Sbjct: 403  LGSTTMDISTI 371
>01494
          Length = 2122

 Score = 51.6 bits (122), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 26/65 (40%), Positives = 40/65 (61%), Gaps = 2/65 (3%)
 Frame = +3

Query: 1087 FHAVCQVIAMYDYMANNEDELNFSKGQLINVMNKDDPDWWQGETNGLT-GLFPSNYV-KM 1144
            F    +V A++DY AN +DEL+F KG +I  +++ D  WW+G+        FPSN+V ++
Sbjct: 294  FTTKLRVKALHDYNANRDDELSFCKGAIITNVSRQDGGWWRGDYGAKKQHWFPSNFVEEI 473

Query: 1145 TTDSD 1149
             T SD
Sbjct: 474  ETHSD 488

 Score = 42.7 bits (99), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 29/85 (34%), Positives = 39/85 (45%), Gaps = 13/85 (15%)
 Frame = +1

Query: 1549 GKSNPYCEVSM-----GSQSYTTRTLQDT-LNPKWNFNCQFFIKDLYQDVLC-------L 1595
            G ++P+ E+ +      +Q + T T  D  LNP WN NC F       DVLC        
Sbjct: 1213 GIASPFVEIEVTGXECDNQKFKTGTRVDNGLNPVWNENCVF-------DVLCPEMALLRF 1371

Query: 1596 TMFDRDQFSPDDFLGRTEVPVAKIR 1620
             + D D F   +FLG+   PV  IR
Sbjct: 1372 AVMDEDIFGDPNFLGQAXFPVPCIR 1446

 Score = 40.0 bits (92), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 21/58 (36%), Positives = 31/58 (53%), Gaps = 1/58 (1%)
 Frame = +3

Query: 721 VNYRALYPFEARNHDEMSFSSGDIIQVDEKTVGEPGWLYGSFQGKF-GWFPCNYVEKV 777
           +  +AL+ + A   DE+SF  G II    +  G  GW  G +  K   WFP N+VE++
Sbjct: 306 LRVKALHDYNANRDDELSFCKGAIITNVSRQDG--GWWRGDYGAKKQHWFPSNFVEEI 473

 Score = 38.1 bits (87), Expect = 0.027,   Method: Compositional matrix adjust.
 Identities = 19/49 (38%), Positives = 31/49 (63%), Gaps = 2/49 (4%)
 Frame = +3

Query: 949 ALYSYSSVEPGDLTFTEGEEIL-VTQKDGEWWTGSIG-ERTGIFPSNYV 995
           AL+ Y++    +L+F +G  I  V+++DG WW G  G ++   FPSN+V
Sbjct: 318 ALHDYNANRDDELSFCKGAIITNVSRQDGGWWRGDYGAKKQHWFPSNFV 464

 Score = 37.4 bits (85), Expect = 0.045,   Method: Compositional matrix adjust.
 Identities = 26/92 (28%), Positives = 43/92 (46%), Gaps = 2/92 (2%)
 Frame = +3

Query: 985  ERTGIF--PSNYVRPKDQENFGNASKSGASNKKPEIAQVTSAYAASGTEQLSLAPGQLIL 1042
            + TGI+  P  Y+ P D   F    +  A +           Y A+  ++LS   G +I 
Sbjct: 243  DETGIYGAPDVYINPND---FTTKLRVKALHD----------YNANRDDELSFCKGAIIT 383

Query: 1043 ILKKNTSGWWQGELQARGKKRQKGWFPASHVK 1074
             + +   GWW+G+    G K+Q  WFP++ V+
Sbjct: 384  NVSRQDGGWWRGDY---GAKKQH-WFPSNFVE 467
>17286
          Length = 489

 Score = 50.4 bits (119), Expect = 6e-06,   Method: Composition-based stats.
 Identities = 18/50 (36%), Positives = 35/50 (70%)
 Frame = +3

Query: 1095 AMYDYMANNEDELNFSKGQLINVMNKDDPDWWQGETNGLTGLFPSNYVKM 1144
            A+YD++  ++ EL F +G +I ++++ D +W++G  +G  G FP NYV++
Sbjct: 36   AIYDFLPESDGELGFQEGDMITLISQVDENWFEGSVHGKVGYFPINYVEV 185

 Score = 48.9 bits (115), Expect = 1e-05,   Method: Composition-based stats.
 Identities = 26/59 (44%), Positives = 32/59 (54%), Gaps = 4/59 (6%)
 Frame = +3

Query: 724 RALYPFEARNHDEMSFSSGDII----QVDEKTVGEPGWLYGSFQGKFGWFPCNYVEKVL 778
           RA+Y F   +  E+ F  GD+I    QVDE       W  GS  GK G+FP NYVE V+
Sbjct: 33  RAIYDFLPESDGELGFQEGDMITLISQVDEN------WFEGSVHGKVGYFPINYVEVVV 191

 Score = 45.4 bits (106), Expect = 2e-04,   Method: Composition-based stats.
 Identities = 20/53 (37%), Positives = 35/53 (66%), Gaps = 1/53 (1%)
 Frame = +3

Query: 857 AQALCSWTAKKENHLNFSKHDVITVLEQ-QENWWFGEVHGGRGWFPKSYVKLI 908
           A+A+  +  + +  L F + D+IT++ Q  ENW+ G VHG  G+FP +YV+++
Sbjct: 30  ARAIYDFLPESDGELGFQEGDMITLISQVDENWFEGSVHGKVGYFPINYVEVV 188

 Score = 42.7 bits (99), Expect = 0.001,   Method: Composition-based stats.
 Identities = 20/48 (41%), Positives = 29/48 (60%), Gaps = 1/48 (2%)
 Frame = +3

Query: 949 ALYSYSSVEPGDLTFTEGEEI-LVTQKDGEWWTGSIGERTGIFPSNYV 995
           A+Y +     G+L F EG+ I L++Q D  W+ GS+  + G FP NYV
Sbjct: 36  AIYDFLPESDGELGFQEGDMITLISQVDENWFEGSVHGKVGYFPINYV 179
>29687
          Length = 434

 Score = 49.7 bits (117), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 27/69 (39%), Positives = 41/69 (59%), Gaps = 2/69 (2%)
 Frame = -2

Query: 1087 FHAVCQVIAMYDYMANNEDELNFSKGQLINVMNKDDPDWWQGETNGLT-GLFPSNYV-KM 1144
            F    +V A++DY A  EDEL+F KG +I  +++ D  WW+G+        FPSNYV ++
Sbjct: 310  FTTKLRVKALHDYNAKREDELSFCKGAIITNVSRQDGGWWRGDYGTKKQHWFPSNYVEEI 131

Query: 1145 TTDSDPSQQ 1153
             T +D S +
Sbjct: 130  DTQTDSSNE 104

 Score = 41.2 bits (95), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 22/55 (40%), Positives = 31/55 (56%), Gaps = 1/55 (1%)
 Frame = -2

Query: 724 RALYPFEARNHDEMSFSSGDIIQVDEKTVGEPGWLYGSF-QGKFGWFPCNYVEKV 777
           +AL+ + A+  DE+SF  G II    +  G  GW  G +   K  WFP NYVE++
Sbjct: 289 KALHDYNAKREDELSFCKGAIITNVSRQDG--GWWRGDYGTKKQHWFPSNYVEEI 131

 Score = 39.3 bits (90), Expect = 0.013,   Method: Compositional matrix adjust.
 Identities = 21/55 (38%), Positives = 33/55 (60%), Gaps = 2/55 (3%)
 Frame = -2

Query: 949  ALYSYSSVEPGDLTFTEGEEIL-VTQKDGEWWTGSIG-ERTGIFPSNYVRPKDQE 1001
            AL+ Y++    +L+F +G  I  V+++DG WW G  G ++   FPSNYV   D +
Sbjct: 286  ALHDYNAKREDELSFCKGAIITNVSRQDGGWWRGDYGTKKQHWFPSNYVEEIDTQ 122

 Score = 37.7 bits (86), Expect = 0.034,   Method: Compositional matrix adjust.
 Identities = 17/50 (34%), Positives = 29/50 (58%)
 Frame = -2

Query: 1025 YAASGTEQLSLAPGQLILILKKNTSGWWQGELQARGKKRQKGWFPASHVK 1074
            Y A   ++LS   G +I  + +   GWW+G+    G K+Q  WFP+++V+
Sbjct: 274  YNAKREDELSFCKGAIITNVSRQDGGWWRGDY---GTKKQH-WFPSNYVE 137
>26032
          Length = 465

 Score = 46.6 bits (109), Expect = 7e-05,   Method: Composition-based stats.
 Identities = 18/42 (42%), Positives = 32/42 (76%), Gaps = 1/42 (2%)
 Frame = +2

Query: 868 ENHLNFSKHDVITVLEQQ-ENWWFGEVHGGRGWFPKSYVKLI 908
           ++ L F K+D+IT++ Q+ E+ W GE++G RGWFP  +V+++
Sbjct: 47  DDELGFRKNDIITLISQKDEHCWIGELNGLRGWFPAKFVEVL 172

 Score = 45.4 bits (106), Expect = 2e-04,   Method: Composition-based stats.
 Identities = 18/47 (38%), Positives = 31/47 (65%)
 Frame = +2

Query: 1098 DYMANNEDELNFSKGQLINVMNKDDPDWWQGETNGLTGLFPSNYVKM 1144
            D+  +++DEL F K  +I ++++ D   W GE NGL G FP+ +V++
Sbjct: 29   DFERHDDDELGFRKNDIITLISQKDEHCWIGELNGLRGWFPAKFVEV 169

 Score = 34.7 bits (78), Expect = 0.32,   Method: Composition-based stats.
 Identities = 18/47 (38%), Positives = 24/47 (51%)
 Frame = +2

Query: 729 FEARNHDEMSFSSGDIIQVDEKTVGEPGWLYGSFQGKFGWFPCNYVE 775
           FE  + DE+ F   DII +  +   E  W+ G   G  GWFP  +VE
Sbjct: 32  FERHDDDELGFRKNDIITLISQK-DEHCWI-GELNGLRGWFPAKFVE 166
>32146
          Length = 715

 Score = 45.1 bits (105), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 36/137 (26%), Positives = 68/137 (49%), Gaps = 18/137 (13%)
 Frame = +2

Query: 1394 RKLLHSGKLYKTKSNK--ELHAFLFNDFLLLTYLVRQF-AAASGHEKLFNSK---SSAQF 1447
            R+LLH G L   +S K  +++AFLF+D LL+T + +       G E    S        +
Sbjct: 77   RQLLHEGPLTLMESPKPIDVYAFLFDDMLLITKIKKSARKQKQGLESALRSPHGGDGTSY 256

Query: 1448 RMYKTPIFLNEVLVKLPTDPSSD------EPVFHISHIDR------VYTLRTDNINERTA 1495
             +++ P+ ++  +  L   P+SD      + VF + H+ R      ++TL+T +   +  
Sbjct: 257  VVFRQPLAMDRFI--LHDIPASDLSANGLKQVFVLVHLSRFQQILGIFTLQTSSDTAKGT 430

Query: 1496 WVQKIKGASEQYIDTEK 1512
            W+  I+ A E+Y + ++
Sbjct: 431  WLTAIREAQERYAEKQQ 481
>13664
          Length = 507

 Score = 44.7 bits (104), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 17/38 (44%), Positives = 24/38 (63%)
 Frame = +2

Query: 1092 QVIAMYDYMANNEDELNFSKGQLINVMNKDDPDWWQGE 1129
            +V+A+YDY A   DEL    G +I +++KD   WW GE
Sbjct: 368  KVVALYDYKAQRSDELTILSGDVIMLLHKDSESWWMGE 481

 Score = 37.4 bits (85), Expect = 0.057,   Method: Compositional matrix adjust.
 Identities = 15/46 (32%), Positives = 27/46 (58%)
 Frame = +2

Query: 1011 ASNKKPEIAQVTSAYAASGTEQLSLAPGQLILILKKNTSGWWQGEL 1056
             S +KP+       Y A  +++L++  G +I++L K++  WW GEL
Sbjct: 347  GSTRKPKKVVALYDYKAQRSDELTILSGDVIMLLHKDSESWWMGEL 484

 Score = 35.8 bits (81), Expect = 0.15,   Method: Compositional matrix adjust.
 Identities = 32/116 (27%), Positives = 54/116 (46%), Gaps = 5/116 (4%)
 Frame = +2

Query: 873 FSKHDVITVLEQQENWW--FGEV--HGGRGWFPKSYVKLIPGNEVQRGEPEALYAAVTKK 928
           F+ H++   ++Q ++W   F EV  HGG+     +Y    P   +   + +A +      
Sbjct: 182 FTSHNM--YMKQSDSWRPSFSEVGRHGGKS---SAYFGRPPQIALDNSQGKAQF------ 328

Query: 929 PTSTAYPVTSTAYPVGEDYIALYSYSSVEPGDLTFTEGEEILVTQKDGE-WWTGSI 983
             S   P+ ST  P  +  +ALY Y +    +LT   G+ I++  KD E WW G +
Sbjct: 329 --SFQSPLGSTRKP--KKVVALYDYKAQRSDELTILSGDVIMLLHKDSESWWMGEL 484

 Score = 31.2 bits (69), Expect = 4.0,   Method: Compositional matrix adjust.
 Identities = 16/46 (34%), Positives = 25/46 (54%), Gaps = 1/46 (2%)
 Frame = +2

Query: 856 KAQALCSWTAKKENHLNFSKHDVITVLEQ-QENWWFGEVHGGRGWF 900
           K  AL  + A++ + L     DVI +L +  E+WW GE+  G+  F
Sbjct: 368 KVVALYDYKAQRSDELTILSGDVIMLLHKDSESWWMGELLDGQQGF 505
>28095
          Length = 597

 Score = 43.9 bits (102), Expect = 5e-04,   Method: Composition-based stats.
 Identities = 24/56 (42%), Positives = 31/56 (55%), Gaps = 2/56 (3%)
 Frame = +3

Query: 1090 VCQVIAMYDYMANNEDELNFSKGQLINVMNKDDPDWWQG--ETNGLTGLFPSNYVK 1143
            VC+  AMYDY A + DE++F+ G  I      D  W  G  E  G  G+ PSNYV+
Sbjct: 261  VCK--AMYDYQAADSDEVSFNDGDTIIECQPVDAGWMTGRVERTGQYGMLPSNYVE 422

 Score = 38.9 bits (89), Expect = 0.018,   Method: Composition-based stats.
 Identities = 20/51 (39%), Positives = 31/51 (60%), Gaps = 4/51 (7%)
 Frame = +3

Query: 949 ALYSYSSVEPGDLTFTEGEEILVTQK-DGEWWTGSIGERT---GIFPSNYV 995
           A+Y Y + +  +++F +G+ I+  Q  D  W TG + ERT   G+ PSNYV
Sbjct: 270 AMYDYQAADSDEVSFNDGDTIIECQPVDAGWMTGRV-ERTGQYGMLPSNYV 419
>11641
          Length = 2509

 Score = 43.5 bits (101), Expect = 7e-04,   Method: Composition-based stats.
 Identities = 18/58 (31%), Positives = 36/58 (62%)
 Frame = -1

Query: 1304 LSSFLLKPMQRITRYPLLIRSILENTPQSHVDHSSLKLALERAEELCSQVNEGVREKE 1361
            + + L+KP+QRI +YPLL+  + ++T   H D +++  A+    ++ + +NE  R K+
Sbjct: 2371 VEAMLIKPVQRILKYPLLLNELFKSTEDDHPDKTAIGNAIRAMTDVATAINEYKRRKD 2198

 Score = 32.3 bits (72), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 24/99 (24%), Positives = 44/99 (44%), Gaps = 12/99 (12%)
 Frame = -1

Query: 917  EPEALYAAVTK-------KPTSTAYPVTSTAYPVGEDYIALYSYSSVEPGDLTFTEGEEI 969
            +P ++Y  +T+       +P S+A P +   Y     Y A + + +    ++T   G+ +
Sbjct: 925  QPASVYPQITQVSQPDPAQPVSSAEPASQHEY-----YCADFPFQARSSNEVTLFAGQVV 761

Query: 970  LVTQK---DG--EWWTGSIGERTGIFPSNYVRPKDQENF 1003
            +V  +   DG  EWW        G  P++Y+R     NF
Sbjct: 760  VVLNRQDLDGNTEWWLVDADGYQGYAPASYLRKM*WSNF 644
>14539
          Length = 436

 Score = 42.4 bits (98), Expect = 0.001,   Method: Composition-based stats.
 Identities = 28/86 (32%), Positives = 40/86 (46%), Gaps = 13/86 (15%)
 Frame = +3

Query: 1549 GKSNPYCEVSMG-----SQSYTTRTLQDT-LNPKWNFNCQFFIKDLYQDVLC-------L 1595
            G ++P+ E+ +      +Q + T T  D  LNP WN NC F       DVLC        
Sbjct: 72   GIASPFLEIEIAGIECDNQKFKTETRVDNGLNPVWNKNCVF-------DVLCPELALLRF 230

Query: 1596 TMFDRDQFSPDDFLGRTEVPVAKIRT 1621
             + D D F   +FLG+   PV  I++
Sbjct: 231  AVMDEDTFGDPNFLGQGCFPVPCIKS 308
>18372
          Length = 468

 Score = 42.0 bits (97), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 24/82 (29%), Positives = 40/82 (48%)
 Frame = +2

Query: 1248 IGDILAAELSHMQAYIRFCSCQLNGATLLQQKTDEDTDFKEFLKKLASDPRCKGMPLSSF 1307
            +G          Q Y  +C  +     L  +  D +  FK+  ++L        +PL ++
Sbjct: 38   VGRCFVNRKEEFQMYSTYCQNKPKSEALRMRVGDSNPFFKDCQQRLGHK-----LPLGAY 202

Query: 1308 LLKPMQRITRYPLLIRSILENT 1329
            LLKP+QRIT+Y LL++ +L  T
Sbjct: 203  LLKPVQRITKYQLLLKEMLRFT 268
>17768
          Length = 492

 Score = 41.2 bits (95), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 21/65 (32%), Positives = 37/65 (56%)
 Frame = -1

Query: 1265 FCSCQLNGATLLQQKTDEDTDFKEFLKKLASDPRCKGMPLSSFLLKPMQRITRYPLLIRS 1324
            +C    N  T L+ K  ++++F EF +    D RCK + L+  L+ P+Q  T+ PLL+ +
Sbjct: 270  YCINYTNALTYLE-KLRQNSEFAEFERWCEQDARCKRLQLTDLLVAPIQHCTKLPLLLAN 94

Query: 1325 ILENT 1329
            + + T
Sbjct: 93   VAKYT 79
>33143
          Length = 1469

 Score = 39.7 bits (91), Expect = 0.010,   Method: Compositional matrix adjust.
 Identities = 18/69 (26%), Positives = 34/69 (49%), Gaps = 3/69 (4%)
 Frame = -2

Query: 1089 AVCQVIAMYDYMANNEDELNFSKGQLINVMN---KDDPDWWQGETNGLTGLFPSNYVKMT 1145
            A+    A+  Y A+  DE++   G  ++V++    +   WW+G+     G FP++ V++ 
Sbjct: 442  AIAAAHAVKPYAAHASDEISLQVGDFVSVIDMPSSEGTKWWRGKKGFEVGFFPADCVEVI 263

Query: 1146 TDSDPSQQW 1154
             D  P   W
Sbjct: 262  RDKVPVSMW 236
>19469
          Length = 428

 Score = 39.7 bits (91), Expect = 0.011,   Method: Compositional matrix adjust.
 Identities = 18/55 (32%), Positives = 29/55 (52%), Gaps = 3/55 (5%)
 Frame = -1

Query: 1095 AMYDYMANNEDELNFSKGQLINVMNKDDP---DWWQGETNGLTGLFPSNYVKMTT 1146
            A+YD +A   DEL F +G +I ++ +D      WW     G  G+ P N +K+ +
Sbjct: 353  ALYDNIAETPDELAFRRGDVITILEQDTAGLDGWWLCSLRGRQGIAPGNRLKILS 189

 Score = 37.7 bits (86), Expect = 0.037,   Method: Compositional matrix adjust.
 Identities = 23/58 (39%), Positives = 33/58 (56%), Gaps = 1/58 (1%)
 Frame = -1

Query: 724 RALYPFEARNHDEMSFSSGDIIQVDEK-TVGEPGWLYGSFQGKFGWFPCNYVEKVLSS 780
           +ALY   A   DE++F  GD+I + E+ T G  GW   S +G+ G  P N + K+LS 
Sbjct: 356 KALYDNIAETPDELAFRRGDVITILEQDTAGLDGWWLCSLRGRQGIAPGNRL-KILSG 186

 Score = 37.4 bits (85), Expect = 0.048,   Method: Compositional matrix adjust.
 Identities = 20/58 (34%), Positives = 32/58 (55%), Gaps = 4/58 (6%)
 Frame = -1

Query: 857 AQALCSWTAKKENHLNFSKHDVITVLEQQ----ENWWFGEVHGGRGWFPKSYVKLIPG 910
           A+AL    A+  + L F + DVIT+LEQ     + WW   + G +G  P + +K++ G
Sbjct: 359 AKALYDNIAETPDELAFRRGDVITILEQDTAGLDGWWLCSLRGRQGIAPGNRLKILSG 186

 Score = 32.3 bits (72), Expect = 1.7,   Method: Compositional matrix adjust.
 Identities = 17/52 (32%), Positives = 26/52 (50%), Gaps = 4/52 (7%)
 Frame = -1

Query: 949 ALYSYSSVEPGDLTFTEGEEILVTQKDGE----WWTGSIGERTGIFPSNYVR 996
           ALY   +  P +L F  G+ I + ++D      WW  S+  R GI P N ++
Sbjct: 353 ALYDNIAETPDELAFRRGDVITILEQDTAGLDGWWLCSLRGRQGIAPGNRLK 198
>05237
          Length = 472

 Score = 39.3 bits (90), Expect = 0.012,   Method: Composition-based stats.
 Identities = 21/60 (35%), Positives = 34/60 (56%), Gaps = 2/60 (3%)
 Frame = +3

Query: 250 RQKFNSLDKGMSGYLSGFQARNAL--LQSNLSQTQLATIWTLADIDGDGQLKAEEFILAM 307
           R+ F   DK  +G++S  + R+ +  L   L+  ++  +   ADIDGDGQ+  EEF+  M
Sbjct: 36  REAFRVFDKDGNGFISASELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVKMM 215
>15115
          Length = 443

 Score = 39.3 bits (90), Expect = 0.012,   Method: Composition-based stats.
 Identities = 16/47 (34%), Positives = 29/47 (61%), Gaps = 1/47 (2%)
 Frame = -2

Query: 1099 YMANNEDELNFSKGQLINVMNKDDPDWWQG-ETNGLTGLFPSNYVKM 1144
            + A ++ E+ F    +I  +++ D  WWQG   +G  G+FP+NYV++
Sbjct: 433  HQAGDDTEITFDPDDIITNIDQIDEGWWQGFAPDGSYGMFPANYVEL 293

 Score = 32.0 bits (71), Expect = 2.2,   Method: Composition-based stats.
 Identities = 20/51 (39%), Positives = 27/51 (52%), Gaps = 5/51 (9%)
 Frame = -2

Query: 730 EARNHDEMSFSSGDII----QVDEKTVGEPGWLYG-SFQGKFGWFPCNYVE 775
           +A +  E++F   DII    Q+DE      GW  G +  G +G FP NYVE
Sbjct: 430 QAGDDTEITFDPDDIITNIDQIDE------GWWQGFAPDGSYGMFPANYVE 296
>14594
          Length = 1014

 Score = 39.3 bits (90), Expect = 0.014,   Method: Composition-based stats.
 Identities = 20/60 (33%), Positives = 33/60 (55%), Gaps = 2/60 (3%)
 Frame = +3

Query: 250 RQKFNSLDKGMSGYLSGFQARNAL--LQSNLSQTQLATIWTLADIDGDGQLKAEEFILAM 307
           R+ F   DK  +GY+S  + R+ +  L   L+  ++  +   AD+DGDG +  EEF+  M
Sbjct: 669 REAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIKEADLDGDGMVNYEEFVTMM 848
>18050
          Length = 448

 Score = 38.9 bits (89), Expect = 0.016,   Method: Composition-based stats.
 Identities = 20/54 (37%), Positives = 29/54 (53%), Gaps = 2/54 (3%)
 Frame = +3

Query: 1092 QVIAMYDYMANNEDELNFSKGQLINVMNKDDPDWWQGE--TNGLTGLFPSNYVK 1143
            QVIA + Y ++  D L    G ++NV  K    W+QGE   +G  G FP +Y +
Sbjct: 21   QVIAKHSYESDEPDVLQLELGDVVNVSRKLPDGWYQGERIRDGAVGWFPGSYTE 182

 Score = 33.5 bits (75), Expect = 0.66,   Method: Composition-based stats.
 Identities = 18/59 (30%), Positives = 30/59 (50%)
 Frame = +3

Query: 1024 AYAASGTEQLSLAPGQLILILKKNTSGWWQGELQARGKKRQKGWFPASHVKLLGPSSER 1082
            +Y +   + L L  G ++ + +K   GW+QGE   R +    GWFP S+ + L  +  R
Sbjct: 39   SYESDEPDVLQLELGDVVNVSRKLPDGWYQGE---RIRDGAVGWFPGSYTEELNSAHVR 206
>29243
          Length = 1147

 Score = 38.9 bits (89), Expect = 0.019,   Method: Compositional matrix adjust.
 Identities = 22/58 (37%), Positives = 31/58 (53%), Gaps = 2/58 (3%)
 Frame = +2

Query: 1018 IAQVTSAYAASGTEQLSLAPGQLILILKKN--TSGWWQGELQARGKKRQKGWFPASHV 1073
             A     YAA+ T QLS+     I IL KN    GWW+GE     + ++ G+FP ++V
Sbjct: 635  FAVAVYDYAATSTSQLSMKLNDRIAILSKNGQDKGWWKGE---NLRTQKIGYFPLAYV 799
>36643
          Length = 601

 Score = 38.5 bits (88), Expect = 0.022,   Method: Compositional matrix adjust.
 Identities = 27/85 (31%), Positives = 43/85 (50%), Gaps = 3/85 (3%)
 Frame = +1

Query: 702 TQEEERKAEAKQSETASALVNYRALYPFEARNHDEMSFSSGDIIQVDEKTVGEP---GWL 758
           TQEEE  A+ +     +     + L+ F  +  +E+SFS+G  + +  K V +P   GWL
Sbjct: 148 TQEEESWAKGETDHVVA-----QTLFSFTGQGEEELSFSAGQQLILAPKEV-QPQVRGWL 309

Query: 759 YGSFQGKFGWFPCNYVEKVLSSEKA 783
             S  G+ G  P NY+ K+L   + 
Sbjct: 310 LASVGGRKGLVPYNYI-KILGKRRG 381

 Score = 33.1 bits (74), Expect = 0.90,   Method: Compositional matrix adjust.
 Identities = 14/52 (26%), Positives = 31/52 (59%), Gaps = 5/52 (9%)
 Frame = +1

Query: 950 LYSYSSVEPGDLTFTEGEEILVTQKDGE-----WWTGSIGERTGIFPSNYVR 996
           L+S++     +L+F+ G+++++  K+ +     W   S+G R G+ P NY++
Sbjct: 205 LFSFTGQGEEELSFSAGQQLILAPKEVQPQVRGWLLASVGGRKGLVPYNYIK 360
>21187
          Length = 1206

 Score = 38.5 bits (88), Expect = 0.022,   Method: Compositional matrix adjust.
 Identities = 18/55 (32%), Positives = 30/55 (54%), Gaps = 3/55 (5%)
 Frame = +2

Query: 1092 QVIAMYDYMANNEDELNFSKGQLINVMNK---DDPDWWQGETNGLTGLFPSNYVK 1143
            +  A+  Y A++   L  ++G ++ + +K   + PD W GE NG  G FP  +VK
Sbjct: 128  KATAIGRYPASSPLYLTLNRGDIVEIKSKSAGNRPDLWGGEVNGRKGYFPKAFVK 292

 Score = 38.1 bits (87), Expect = 0.031,   Method: Compositional matrix adjust.
 Identities = 17/55 (30%), Positives = 33/55 (60%), Gaps = 4/55 (7%)
 Frame = +2

Query: 856 KAQALCSWTAKKENHLNFSKHDVITVLEQ----QENWWFGEVHGGRGWFPKSYVK 906
           KA A+  + A    +L  ++ D++ +  +    + + W GEV+G +G+FPK++VK
Sbjct: 128 KATAIGRYPASSPLYLTLNRGDIVEIKSKSAGNRPDLWGGEVNGRKGYFPKAFVK 292
>38272
          Length = 749

 Score = 38.1 bits (87), Expect = 0.032,   Method: Composition-based stats.
 Identities = 38/158 (24%), Positives = 71/158 (44%), Gaps = 2/158 (1%)
 Frame = +2

Query: 1304 LSSFLLKPMQRITRYPLLIRSILENTPQS--HVDHSSLKLALERAEELCSQVNEGVREKE 1361
            LS+ ++ P+QRIT+Y LLI  IL  T ++  H + ++L  A E+ +++  +VN+ +    
Sbjct: 113  LSALIITPVQRITKYVLLINEILRETKRAGLHNEVATLMEAGEQMKDVVKKVNDMMMVLR 292

Query: 1362 NSDRLEWIQAHVQCEGLAEQLIFNSLTNCLGPRKLLHSGKLYKTKSNKELHAFLFNDFLL 1421
                L+     +  +G    L+   +  C           +   +  +EL  FLF   ++
Sbjct: 293  G---LQDFDGEITAQG---NLLLQGILTC----------AIDAGQKQRELQVFLFQQIII 424

Query: 1422 LTYLVRQFAAASGHEKLFNSKSSAQFRMYKTPIFLNEV 1459
               +          +K+    SS  F+ Y+T I LN +
Sbjct: 425  FADI----------QKVKTQXSSPIFK-YRTHIQLNHM 505
>31183
          Length = 923

 Score = 37.0 bits (84), Expect = 0.062,   Method: Composition-based stats.
 Identities = 19/44 (43%), Positives = 24/44 (54%)
 Frame = +1

Query: 1122 DPDWWQGETNGLTGLFPSNYVKMTTDSDPSQQWCADLQALDTMQ 1165
            D  WW+G  +G  GLFP+NYV++       QQ    LQA  T Q
Sbjct: 31   DDGWWRGSCHGKNGLFPANYVEL-------QQ*FPLLQAASTQQ 141

 Score = 37.0 bits (84), Expect = 0.068,   Method: Composition-based stats.
 Identities = 16/32 (50%), Positives = 20/32 (62%), Gaps = 1/32 (3%)
 Frame = +1

Query: 877 DVITVLEQ-QENWWFGEVHGGRGWFPKSYVKL 907
           DVIT +E   + WW G  HG  G FP +YV+L
Sbjct: 4   DVITDIEMIDDGWWRGSCHGKNGLFPANYVEL 99

 Score = 32.3 bits (72), Expect = 1.8,   Method: Composition-based stats.
 Identities = 16/33 (48%), Positives = 18/33 (54%)
 Frame = +1

Query: 743 DIIQVDEKTVGEPGWLYGSFQGKFGWFPCNYVE 775
           DI  +D+      GW  GS  GK G FP NYVE
Sbjct: 16  DIEMIDD------GWWRGSCHGKNGLFPANYVE 96

 Score = 32.0 bits (71), Expect = 1.9,   Method: Composition-based stats.
 Identities = 21/76 (27%), Positives = 31/76 (40%)
 Frame = +1

Query: 975  DGEWWTGSIGERTGIFPSNYVRPKDQENFGNASKSGASNKKPEIAQVTSAYAASGTEQLS 1034
            D  WW GS   + G+FP+NYV                     E+ Q      A+ T+Q +
Sbjct: 31   DDGWWRGSCHGKNGLFPANYV---------------------ELQQ*FPLLQAASTQQRA 147

Query: 1035 LAPGQLILILKKNTSG 1050
            +    L++I    TSG
Sbjct: 148  VGDTMLLMIPCVQTSG 195
>27252
          Length = 378

 Score = 36.6 bits (83), Expect = 0.088,   Method: Compositional matrix adjust.
 Identities = 22/63 (34%), Positives = 31/63 (49%), Gaps = 2/63 (3%)
 Frame = +2

Query: 1016 PEIAQVTSAYAASGTE--QLSLAPGQLILILKKNTSGWWQGELQARGKKRQKGWFPASHV 1073
            P +A+V      S  +  QL L  G+ I +L  N  G W+GE+  R      G FP +HV
Sbjct: 116  PALARVILDRTPSAYDRTQLKLKQGETIKVLAINIDGQWEGEINGR-----TGKFPFTHV 280

Query: 1074 KLL 1076
            + L
Sbjct: 281  EFL 289
>01019
          Length = 1705

 Score = 36.6 bits (83), Expect = 0.089,   Method: Composition-based stats.
 Identities = 19/54 (35%), Positives = 31/54 (57%), Gaps = 2/54 (3%)
 Frame = +1

Query: 256 LDKGMSGYLSGFQARNAL--LQSNLSQTQLATIWTLADIDGDGQLKAEEFILAM 307
            DK  +G++S  + R+ +  L   L+  ++  +   ADIDGDGQ+  EEF+  M
Sbjct: 46  FDKDGNGFISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVTMM 207
>30740
          Length = 488

 Score = 36.2 bits (82), Expect = 0.11,   Method: Compositional matrix adjust.
 Identities = 11/35 (31%), Positives = 25/35 (71%)
 Frame = +2

Query: 1092 QVIAMYDYMANNEDELNFSKGQLINVMNKDDPDWW 1126
            +++  YD+   + ++L FSKG ++ +++KD+ +WW
Sbjct: 188  KLMGKYDFSGRDPEDLPFSKGDILELISKDEEEWW 292
>19562
          Length = 457

 Score = 36.2 bits (82), Expect = 0.11,   Method: Composition-based stats.
 Identities = 19/64 (29%), Positives = 30/64 (46%), Gaps = 1/64 (1%)
 Frame = -1

Query: 1539 ATELKACKPNGKSNPYCEVSMGSQSY-TTRTLQDTLNPKWNFNCQFFIKDLYQDVLCLTM 1597
            + + +  +  G S+PYC +    +   TT  +  T NP+W    +FFI D  Q      +
Sbjct: 433  SQQREGSRQTGASDPYCVLFCNRRRLLTTPYVPATRNPRWESWAEFFIGDFTQSTYSFFV 254

Query: 1598 FDRD 1601
            FD D
Sbjct: 253  FDWD 242
>14366
          Length = 499

 Score = 33.9 bits (76), Expect = 0.60,   Method: Compositional matrix adjust.
 Identities = 19/60 (31%), Positives = 31/60 (51%), Gaps = 2/60 (3%)
 Frame = -3

Query: 250 RQKFNSLDKGMSGYLSGFQARNAL--LQSNLSQTQLATIWTLADIDGDGQLKAEEFILAM 307
           R+ F   DK  +G ++  + R+ L  L   LS  ++  +   ADI GDGQ+   +F+  M
Sbjct: 242 REAFRIFDKEGNGMINAAELRHVLTHLGEKLSDEEVDEMIREADISGDGQVSYNDFVKVM 63
>39077
          Length = 640

 Score = 33.1 bits (74), Expect = 0.87,   Method: Compositional matrix adjust.
 Identities = 34/109 (31%), Positives = 56/109 (51%)
 Frame = +1

Query: 496 LEAVNGKHQQISGRLQDVQIRKQTQKTELEVLDKQCDLEIMEIKQLQQELKEYQNKLIYL 555
           +++V+ + +QIS RL DV   K        VLDK+C      + ++  EL+E ++    L
Sbjct: 337 VQSVSSEKRQISQRLADVTKEKH-------VLDKKCSQMHGRLSKVLTELQEERDMNKCL 495

Query: 556 VPEKQLLNERIKNMQLSNTPDSGISLLHKKSSEKEELCQRLKEQLDALE 604
              +QL  ER+  ++ S T     SL   K  E EEL ++L++ +  LE
Sbjct: 496 RENQQLWQERVTALEQSVT-----SLAQAKDKEVEELREQLRDVMFYLE 627
>05206
          Length = 1075

 Score = 32.7 bits (73), Expect = 1.3,   Method: Composition-based stats.
 Identities = 19/53 (35%), Positives = 28/53 (52%), Gaps = 1/53 (1%)
 Frame = +1

Query: 724 RALYPFEARNHDEMSFSSGDIIQVDEKTVGEPGWL-YGSFQGKFGWFPCNYVE 775
           RALYPFEA N   +     + +Q+ E+  G+ GW       G  G+ P +YV+
Sbjct: 100 RALYPFEAMNEGSVPMGENEEMQILEEDQGD-GWTRVRKADGSEGFVPSSYVQ 255
>29179
          Length = 1113

 Score = 32.0 bits (71), Expect = 1.9,   Method: Composition-based stats.
 Identities = 15/32 (46%), Positives = 21/32 (65%)
 Frame = -1

Query: 1526 TSGIGRLMVHVIEATELKACKPNGKSNPYCEV 1557
            +  IGRL V V++A ELKA    G S+PY ++
Sbjct: 117  SPNIGRLTVIVMKAKELKAKDITGSSDPYVKI 22
>07385
          Length = 1292

 Score = 32.0 bits (71), Expect = 2.3,   Method: Composition-based stats.
 Identities = 18/44 (40%), Positives = 25/44 (56%)
 Frame = +3

Query: 264 LSGFQARNALLQSNLSQTQLATIWTLADIDGDGQLKAEEFILAM 307
           +S  Q R A  Q  L+  ++  +   ADIDGDGQ+  EEF+  M
Sbjct: 114 ISAGQLRGARFQ-KLTDEEVDEMIREADIDGDGQVNYEEFVKMM 242
>18881
          Length = 762

 Score = 31.2 bits (69), Expect = 3.5,   Method: Composition-based stats.
 Identities = 20/48 (41%), Positives = 27/48 (56%), Gaps = 2/48 (4%)
 Frame = -3

Query: 1028 SGTEQLSLAPGQLILILKKN--TSGWWQGELQARGKKRQKGWFPASHV 1073
            + T Q++L     I IL KN    GWW+GE   R KK   G+FP ++V
Sbjct: 451  TSTTQVTLKLNDRISILSKNGQDKGWWKGE-NLRTKK--VGYFPLAYV 317
>32088
          Length = 1928

 Score = 30.8 bits (68), Expect = 4.3,   Method: Composition-based stats.
 Identities = 18/56 (32%), Positives = 31/56 (55%), Gaps = 2/56 (3%)
 Frame = +1

Query: 250  RQKFNSLDKGMSGYLSGFQARNAL--LQSNLSQTQLATIWTLADIDGDGQLKAEEF 303
            R  F+S+D   +G++S  +  +A   +  N+   +L TI +  D  GDG+L  +EF
Sbjct: 952  RSVFDSIDDDNNGHISXGELDSAFRAVGLNIPGYELRTIMSKYDASGDGRLNMDEF 1119
>22144
          Length = 634

 Score = 30.8 bits (68), Expect = 5.0,   Method: Compositional matrix adjust.
 Identities = 15/52 (28%), Positives = 27/52 (51%)
 Frame = -1

Query: 1534 VHVIEATELKACKPNGKSNPYCEVSMGSQSYTTRTLQDTLNPKWNFNCQFFI 1585
            V VI+A  L+     G ++PYC +S   +  TT+   + ++P+W     F +
Sbjct: 388  VKVIKAIGLQKQDAQG-ADPYCVISCEGERVTTKVEXNXVDPEWGEAAVFIV 236
>01678
          Length = 2407

 Score = 30.4 bits (67), Expect = 5.8,   Method: Compositional matrix adjust.
 Identities = 22/76 (28%), Positives = 38/76 (50%), Gaps = 11/76 (14%)
 Frame = +2

Query: 15   MWAITSEE-RTKHDKQFDNL--------KPSGGYITGDQARTFFLQSGLPAP--VLAEIW 63
            + AI  E+ R ++ + F+NL        +   G+I  D  RT FL   +P P  +L  + 
Sbjct: 1259 LVAIAQEQLRKRNYESFNNLLESLQHQDRARSGFIECDVLRTVFLSHHVPLPDDMLRAML 1438

Query: 64   ALSDLNKDGKMDQQEF 79
            A +  N++G+   +EF
Sbjct: 1439 ACAPTNQNGEXAYEEF 1486
>01124
          Length = 1372

 Score = 30.4 bits (67), Expect = 6.1,   Method: Composition-based stats.
 Identities = 14/46 (30%), Positives = 23/46 (50%)
 Frame = +1

Query: 110 SPLISARFGMGSMPNLSIHQPLPPVAPIATPLSSATSGTSIPPLMM 155
           S ++ +R G+G   ++ +    PP      P+SSA S    PPL +
Sbjct: 841 SGVVDSRTGVGKARSVKLTSIFPPCLLATPPISSAASVKMXPPLTL 978
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|10946940|ref|NP_067493.1| RAB2A, member RAS oncogene
family [Mus musculus]
         (212 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

08428                                                                 154   2e-38
34468                                                                 126   7e-30
33374                                                                 125   1e-29
01398                                                                 121   2e-28
26083                                                                 107   3e-24
17511                                                                 105   1e-23
05468                                                                 102   1e-22
30760                                                                 102   1e-22
14456                                                                 101   2e-22
07465                                                                  97   3e-21
33794                                                                  95   2e-20
07580                                                                  95   2e-20
01095                                                                  90   7e-19
33380                                                                  89   1e-18
13750                                                                  89   2e-18
11257                                                                  89   2e-18
13901                                                                  87   5e-18
32723                                                                  86   1e-17
01972                                                                  78   1e-16
19006                                                                  81   3e-16
29380                                                                  77   3e-15
34597                                                                  75   4e-15
12339                                                                  73   9e-14
35581                                                                  71   3e-13
26536                                                                  70   5e-13
00858                                                                  70   7e-13
11728                                                                  70   8e-13
27191                                                                  68   2e-12
13745                                                                  68   4e-12
14119                                                                  67   6e-12
19656                                                                  60   6e-10
09204                                                                  59   1e-09
34359                                                                  59   2e-09
25618                                                                  56   1e-08
14775                                                                  55   1e-08
10862                                                                  46   1e-05
31291                                                                  45   2e-05
00552                                                                  44   4e-05
33605                                                                  44   4e-05
08153                                                                  44   4e-05
18509                                                                  42   2e-04
25796                                                                  39   0.002
31932                                                                  38   0.003
09827                                                                  38   0.003
10708                                                                  33   0.066
33890                                                                  28   1.9  
>08428
          Length = 1109

 Score =  154 bits (390), Expect = 2e-38,   Method: Compositional matrix adjust.
 Identities = 70/160 (43%), Positives = 105/160 (65%)
 Frame = -3

Query: 8    KYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIWDTAGQES 67
            K  ++GD+GVGKS ++L+F    ++P  + TIG  F ++ + +DG   + QIWDTAGQE 
Sbjct: 1065 KVCLLGDSGVGKSSIVLRFVTGSYRPSQESTIGASFMSKSLVVDGAGYRFQIWDTAGQEK 886

Query: 68   FRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLEDARQHSNSNMVIMLIGNKSDLESRR 127
            FR++   YYRGAA A++VYD+TR  TF  + +W+++ R     N+V+ + GNK DLE  R
Sbjct: 885  FRALAPMYYRGAAAAVIVYDVTRPRTFKSVKSWIQELRSFGPPNIVLAIAGNKCDLEELR 706

Query: 128  EVKKEEGEAFAREHGLIFMETSAKTASNVEEAFINTAKEI 167
            EV +++ + +A     IF ETSA TA NVEE F   A+++
Sbjct: 705  EVVEKDAQEYASSISAIFGETSAMTAVNVEEMFTELARQL 586
>34468
          Length = 1502

 Score =  126 bits (316), Expect = 7e-30,   Method: Compositional matrix adjust.
 Identities = 63/167 (37%), Positives = 101/167 (60%), Gaps = 5/167 (2%)
 Frame = +1

Query: 6   LFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIWDTAGQ 65
           +FK I+IGD+ VGK+CL  +F   +F    + TIGV+F  + I +D + +KLQ+WDTAGQ
Sbjct: 493 IFKIIVIGDSNVGKTCLTYRFCLGKFPDKTEATIGVDFREKSIQVDSEHLKLQLWDTAGQ 672

Query: 66  ESFR-SITRSYYRGAAGALLVYDITRRDTFNHLTTWLEDARQHSNSNMVI-MLIGNKSDL 123
           E FR S+ + YYR     + VYD+T+  +F ++  W+E+  +H+ +  +  +L+GNK D+
Sbjct: 673 ERFRKSMVQHYYRNVHAVVFVYDMTKMSSFENMPAWIEECDRHNLTKYIPRILVGNKCDV 852

Query: 124 ESRREVKKEEGEAFAREHGLIFMETSAK---TASNVEEAFINTAKEI 167
             R  V     + FA  H +   ETSAK    A++V+  F+  A ++
Sbjct: 853 VERIAVNTNLAQKFADAHNMPLFETSAKDDEKANHVDAIFMTVAHKL 993
>33374
          Length = 489

 Score =  125 bits (314), Expect = 1e-29,   Method: Compositional matrix adjust.
 Identities = 56/116 (48%), Positives = 83/116 (71%)
 Frame = +1

Query: 43  FGARMITIDGKQIKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLE 102
           F  + + +D   +K +IWDTAGQE + S+   YYRGA  A++VYDIT +DTF    TW++
Sbjct: 139 FLTQTVCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNQDTFGRAKTWVK 318

Query: 103 DARQHSNSNMVIMLIGNKSDLESRREVKKEEGEAFAREHGLIFMETSAKTASNVEE 158
           + ++ ++ N+VI L GNK+DL ++R V+ EE +A+A E+ L+FMETSAKTA NV +
Sbjct: 319 ELQRQASPNIVIALAGNKADLANKRMVEFEEAQAYAEENSLLFMETSAKTAMNVND 486

 Score = 38.5 bits (88), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 18/52 (34%), Positives = 30/52 (57%)
 Frame = +2

Query: 7  FKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQ 58
          FK +++G++ VGKS L+L+F   +F    + TIG  F  R   +  +Q  L+
Sbjct: 32 FKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAF*LRQFVLMTQQSSLR 187
>01398
          Length = 1421

 Score =  121 bits (303), Expect = 2e-28,   Method: Compositional matrix adjust.
 Identities = 60/125 (48%), Positives = 80/125 (64%), Gaps = 1/125 (0%)
 Frame = -2

Query: 65   QESFRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLEDARQHSNSNMVIMLI-GNKSDL 123
            QE FRSITRSYYR + G ++VYDIT+R TF +L  W E+AR H   +  I L+ G+KSD 
Sbjct: 1420 QERFRSITRSYYRNSVGVIIVYDITKRSTFENLKQWYEEARNHIEPHKAIFLVLGHKSDR 1241

Query: 124  ESRREVKKEEGEAFAREHGLIFMETSAKTASNVEEAFINTAKEIYEKIQEGVFDINNEAN 183
            E  R+V   EG  FA  HGL F ETSAK+  N+E+ F   AK+ Y+ +Q+G   +    +
Sbjct: 1240 EDARQVTAREGRRFAEMHGLKFFETSAKSGHNIEDVFAQIAKDTYQHLQDGHIRLEEGWD 1061

Query: 184  GIKIG 188
            G+K G
Sbjct: 1060 GVKQG 1046
>26083
          Length = 432

 Score =  107 bits (267), Expect = 3e-24,   Method: Compositional matrix adjust.
 Identities = 46/114 (40%), Positives = 78/114 (68%)
 Frame = +1

Query: 7   FKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIWDTAGQE 66
           FK + +G+  VGK+ L+ +F    F   +  TIG++F ++ + ++ + I+LQ+WDTAGQE
Sbjct: 79  FKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTIRLQLWDTAGQE 258

Query: 67  SFRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLEDARQHSNSNMVIMLIGNK 120
            FRS+  SY R ++ A++VYDIT  ++F+  + W++D R    S+++IML+GNK
Sbjct: 259 RFRSLIPSYIRDSSVAVVVYDITNANSFHQTSKWIDDVRTERGSDVIIMLVGNK 420
>17511
          Length = 483

 Score =  105 bits (262), Expect = 1e-23,   Method: Compositional matrix adjust.
 Identities = 51/122 (41%), Positives = 77/122 (63%), Gaps = 4/122 (3%)
 Frame = -3

Query: 6   LFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIWDTAGQ 65
           L K II+GD+GVGK+ L+ Q+ +K+F   +  TIG +F  + + +D + + +QIWDTAGQ
Sbjct: 367 LLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQIWDTAGQ 188

Query: 66  ESFRSITRSYYRGAAGALLVYDITRRDTFNHLTTW----LEDARQHSNSNMVIMLIGNKS 121
           E F+S+  ++YRGA   +LV+D+T  +TF  L +W    L  A      N   ++IGNK 
Sbjct: 187 ERFQSLGVAFYRGADCCVLVFDVTMPNTFRSLDSWRDEFLIQASPRDPENFPFVVIGNKI 8

Query: 122 DL 123
           DL
Sbjct: 7   DL 2
>05468
          Length = 1558

 Score =  102 bits (254), Expect = 1e-22,   Method: Compositional matrix adjust.
 Identities = 61/173 (35%), Positives = 96/173 (55%), Gaps = 7/173 (4%)
 Frame = -3

Query: 5    YLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQ-IKLQIWDTA 63
            +L+K ++IG+ G GK+ ++ ++  + F   +  TIGV+F  +++  D    I+LQ+WD A
Sbjct: 1544 HLYKILVIGELGTGKTSIIKRYVHQFFSQHYRATIGVDFALKVLNWDADTLIRLQLWDIA 1365

Query: 64   GQESFRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLED----ARQHSNSNMVIMLIGN 119
            GQE F ++TR YY+ A GA +V+D+TR  TF+ +T W  D     +    S +  +L+ N
Sbjct: 1364 GQERFGNMTRVYYKEAVGAFVVFDVTRASTFDAVTKWKNDLDSKVQLADGSPVPCVLLAN 1185

Query: 120  KSDLESRREVKK-EEGEAFAREHGLI-FMETSAKTASNVEEAFINTAKEIYEK 170
            K D      V    + + F  E G I + ETSAK   N++EA       I EK
Sbjct: 1184 KCDQAKEGLVNNTSQMDEFCSEKGFIGWYETSAKENINIDEAARFLVTRILEK 1026
>30760
          Length = 596

 Score =  102 bits (254), Expect = 1e-22,   Method: Compositional matrix adjust.
 Identities = 58/172 (33%), Positives = 93/172 (54%), Gaps = 6/172 (3%)
 Frame = -1

Query: 8   KYIIIGDTGVGKS--CLLLQFTDKRFQPVHDLTIGVEFGARMITIDGK--QIKLQIWDTA 63
           K I+ GD+GVGKS  C +       F   + +T GVE   +++ I     Q++L ++D+A
Sbjct: 524 KCIVTGDSGVGKSSICQVFHSDSAHFPKNYSMTTGVEVLVKLVNIPDSRDQVELYLFDSA 345

Query: 64  GQESFRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLEDARQHSNSNMVI--MLIGNKS 121
           G+E F      ++   +  ++VYD+T   +F+    WLE  R  +  N VI  +L+ NK+
Sbjct: 344 GKEIFSENVTKFWDQPSVVMVVYDVTDETSFSGCVRWLERVRA-AKPNTVIPGVLVANKT 168

Query: 122 DLESRREVKKEEGEAFAREHGLIFMETSAKTASNVEEAFINTAKEIYEKIQE 173
           DL+ RR V ++EG+  A+ HGL + E SAK   N +  F   A   ++  QE
Sbjct: 167 DLDERRRVSRKEGKDLAQSHGLEYFECSAKEMQNTDTPFFCLAHAFHKLYQE 12
>14456
          Length = 1867

 Score =  101 bits (252), Expect = 2e-22,   Method: Compositional matrix adjust.
 Identities = 55/158 (34%), Positives = 85/158 (53%), Gaps = 4/158 (2%)
 Frame = -1

Query: 16   GVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIWDTAGQESFRSITRSY 75
            GVGKS L+ +F   +F      TIGVEF  + + +D +   +QIWDTAGQE F+S+   +
Sbjct: 1111 GVGKSSLMNRFVSNKFDAQSFHTIGVEFLNKDVVVDDETYTMQIWDTAGQERFKSLRTPF 932

Query: 76   YRGAAGALLVYDITRRDTFNHLTTWLED----ARQHSNSNMVIMLIGNKSDLESRREVKK 131
            YRGA   LL + +    +F +L+ W ++    A          +++GNK D+E R+   +
Sbjct: 931  YRGADCCLLTFSVDSMQSFRNLSMWRKEFLYYADIQDGVTFPFVVLGNKIDVEGRQVTNE 752

Query: 132  EEGEAFAREHGLIFMETSAKTASNVEEAFINTAKEIYE 169
            E            + ETSAK A+NVE+AF+   + + E
Sbjct: 751  EARSWCTANSNAPYFETSAKDATNVEKAFLAAVQRLRE 638
>07465
          Length = 1103

 Score = 97.4 bits (241), Expect = 3e-21,   Method: Compositional matrix adjust.
 Identities = 54/160 (33%), Positives = 87/160 (54%)
 Frame = +3

Query: 20  SCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIWDTAGQESFRSITRSYYRGA 79
           S ++ ++    F   +  TIGV+F  R I + G+ ++L +WDTAGQE F +IT++YYRGA
Sbjct: 240 SSMIQRYCKGIFTKDYKKTIGVDFLERQIEVGGEDVRLMLWDTAGQEEFDAITKAYYRGA 419

Query: 80  AGALLVYDITRRDTFNHLTTWLEDARQHSNSNMVIMLIGNKSDLESRREVKKEEGEAFAR 139
              +L +    RD+F  L TW     +     + ++++ NK DL     V+ EE E  A+
Sbjct: 420 QACVLAFSTVDRDSFEALETWKRKV-EDEVGEIGMVIVQNKIDLIDDAVVRPEEAENLAK 596

Query: 140 EHGLIFMETSAKTASNVEEAFINTAKEIYEKIQEGVFDIN 179
           +  L F  TS K   NV+E F   A +   ++  G+ ++N
Sbjct: 597 KLRLRFYRTSVKENMNVDEVFRYLADKYLHQLNTGMDEVN 716
>33794
          Length = 779

 Score = 95.1 bits (235), Expect = 2e-20,   Method: Compositional matrix adjust.
 Identities = 46/125 (36%), Positives = 76/125 (60%)
 Frame = -1

Query: 41  VEFGARMITIDGKQIKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRDTFNHLTTW 100
           V +    I ++GK++KLQIWDT+GQ  F +I RSY RGA G +LVYDIT + +F+ +  W
Sbjct: 692 VAYKTTTILLEGKRVKLQIWDTSGQGRFCTIIRSYSRGAQGIILVYDITNKWSFDGIDRW 513

Query: 101 LEDARQHSNSNMVIMLIGNKSDLESRREVKKEEGEAFAREHGLIFMETSAKTASNVEEAF 160
           L++  +H+   +  +L+GN+  L  +R+V  ++ E +A  + +   E S     N+ E+F
Sbjct: 512 LKEVEEHA-PGIPKVLVGNRLHLAYKRQVAAKQAETYASRNNMSCFEISPLCDFNIRESF 336

Query: 161 INTAK 165
              A+
Sbjct: 335 CELAR 321
>07580
          Length = 921

 Score = 95.1 bits (235), Expect = 2e-20,   Method: Compositional matrix adjust.
 Identities = 50/129 (38%), Positives = 73/129 (56%), Gaps = 1/129 (0%)
 Frame = +3

Query: 46  RMITIDGKQIKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLED-A 104
           + + +DG+Q  L+I DTAG E F ++   Y +   G LL Y IT + TFN L    E   
Sbjct: 177 KQVEVDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFLLAYSITAQSTFNDLQELREQIL 356

Query: 105 RQHSNSNMVIMLIGNKSDLESRREVKKEEGEAFAREHGLIFMETSAKTASNVEEAFINTA 164
           R     ++ ++L+GNK DLE  R V K++G+  AR     F+ETSAK   NV E F++  
Sbjct: 357 RVKDTDDVPMLLVGNKCDLEDERVVGKDQGQGLARSFSCAFLETSAKARINVNEIFMDLV 536

Query: 165 KEIYEKIQE 173
           ++I +K  E
Sbjct: 537 RQINKKSPE 563
>01095
          Length = 1745

 Score = 89.7 bits (221), Expect = 7e-19,   Method: Compositional matrix adjust.
 Identities = 41/84 (48%), Positives = 63/84 (75%)
 Frame = -1

Query: 84   LVYDITRRDTFNHLTTWLEDARQHSNSNMVIMLIGNKSDLESRREVKKEEGEAFAREHGL 143
            +VYDIT +DTF    TW+++ ++ ++ N+VI L GNK+DL ++R V+ EE +A+A E+ L
Sbjct: 1745 VVYDITNQDTFGRAKTWVKELQRQASPNIVIALAGNKADLANKRMVEFEEAQAYAEENSL 1566

Query: 144  IFMETSAKTASNVEEAFINTAKEI 167
            +FMETSAKTA NV + F+  AK++
Sbjct: 1565 LFMETSAKTAMNVNDIFLAIAKKL 1494
>33380
          Length = 282

 Score = 89.4 bits (220), Expect = 1e-18,   Method: Compositional matrix adjust.
 Identities = 38/75 (50%), Positives = 54/75 (72%)
 Frame = +3

Query: 53  KQIKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLEDARQHSNSNM 112
           K++KLQIWDTAGQE +R+IT +YYRGA G +L+YD+T  ++FN +  W    + +S  N 
Sbjct: 54  KRVKLQIWDTAGQERYRTITTAYYRGAMGFILMYDVTNEESFNAVQDWCTQIKTYSWDNA 233

Query: 113 VIMLIGNKSDLESRR 127
            ++L+GNK DLE  R
Sbjct: 234 QVVLVGNKCDLEDER 278
>13750
          Length = 503

 Score = 88.6 bits (218), Expect = 2e-18,   Method: Compositional matrix adjust.
 Identities = 54/149 (36%), Positives = 78/149 (52%), Gaps = 3/149 (2%)
 Frame = -2

Query: 19  KSCLLLQFTDKRFQPVHDLTIGV---EFGARMITIDGKQIKLQIWDTAGQESFRSITRSY 75
           K+CLL ++    F      TI V   EF       D   ++  +WDT G E++RS+  S+
Sbjct: 502 KTCLLRRYQKGFFMDRTMPTIAVLCSEFNESRT--DPLNVRYTLWDTGGAETYRSLWVSH 329

Query: 76  YRGAAGALLVYDITRRDTFNHLTTWLEDARQHSNSNMVIMLIGNKSDLESRREVKKEEGE 135
           +RGA  ALLVYD+T   +F   TT    A   +     ++ +G+K+DLE  R +  E G+
Sbjct: 328 FRGAQVALLVYDVTCEWSFLTATTVWRKALMKNIPEAQVIFVGSKTDLEENRVISTERGQ 149

Query: 136 AFAREHGLIFMETSAKTASNVEEAFINTA 164
           AFA + G  F ETS+ T  NV+  F   A
Sbjct: 148 AFATQCGYTFFETSSVTGKNVDAVFWEIA 62
>11257
          Length = 1102

 Score = 88.6 bits (218), Expect = 2e-18,   Method: Compositional matrix adjust.
 Identities = 44/127 (34%), Positives = 74/127 (58%), Gaps = 5/127 (3%)
 Frame = -2

Query: 48   ITIDGKQIKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLED---- 103
            + +DG+   +QIWDTAGQE ++S+   +YRG    LL + +    +   L+ W ++    
Sbjct: 1047 VVVDGETFTMQIWDTAGQERYKSLRTPFYRGTDCCLLTFSVDNLKSLQSLSDWYDEFVNY 868

Query: 104  ARQHSNSNMVIMLIGNKSDLESRREVKKEEGEAFAREHG-LIFMETSAKTASNVEEAFIN 162
            A    +++   ++IGNK+D+E  REV  E+   + R HG L + ETSAK + NV++AF+ 
Sbjct: 867  ADIQDSASFPFVIIGNKADIEE-REVSSEDAYNWCRTHGNLPYFETSAKDSLNVQQAFLA 691

Query: 163  TAKEIYE 169
              + + E
Sbjct: 690  VVRRLRE 670
>13901
          Length = 962

 Score = 87.0 bits (214), Expect = 5e-18,   Method: Compositional matrix adjust.
 Identities = 41/101 (40%), Positives = 66/101 (65%), Gaps = 1/101 (0%)
 Frame = -3

Query: 1   MAYAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGK-QIKLQI 59
           M+   LFK IIIGD  VGK+  + ++ +  F+  + +TIGV+F  ++I    K  IKLQ+
Sbjct: 303 MSEEVLFKVIIIGDPTVGKTSFVQRYVNDSFRRDYKMTIGVDFALKVIRWSDKCNIKLQL 124

Query: 60  WDTAGQESFRSITRSYYRGAAGALLVYDITRRDTFNHLTTW 100
           WD AGQE F S+TR YY+ A   ++++D+T+++T+ +   W
Sbjct: 123 WDIAGQERFTSMTRVYYKDAHACIVMFDLTQKNTYQNAIRW 1
>32723
          Length = 384

 Score = 85.9 bits (211), Expect = 1e-17,   Method: Compositional matrix adjust.
 Identities = 41/108 (37%), Positives = 65/108 (60%)
 Frame = +2

Query: 65  QESFRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLEDARQHSNSNMVIMLIGNKSDLE 124
           QE FRSIT+SYYR A   +LVYD+  + ++  L  W+ +   ++ + ++  L+GNK D  
Sbjct: 2   QERFRSITQSYYRSANALILVYDVCSQQSYESLPQWIHEIELYAGTKVLAFLVGNKIDQT 181

Query: 125 SRREVKKEEGEAFAREHGLIFMETSAKTASNVEEAFINTAKEIYEKIQ 172
            +RE+    G+ FA  + + F+ETSAK A NVE+ F   A ++  + Q
Sbjct: 182 DKREIPTHIGKEFAERYEMRFLETSAKEADNVEKLFSTIAYQLTAQAQ 325
>01972
          Length = 2359

 Score = 77.8 bits (190), Expect(2) = 1e-16,   Method: Compositional matrix adjust.
 Identities = 41/130 (31%), Positives = 71/130 (54%)
 Frame = +3

Query: 38  TIGVEFGARMITIDGKQIKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRDTFNHL 97
           T+GVE    +      ++K  +WDTAGQE F  +   YY     A++++D+T R T+ ++
Sbjct: 396 TLGVEVHPLLFHTSRGKLKFNVWDTAGQEKFGGLRDGYYIQGQCAVIMFDVTSRVTYKNV 575

Query: 98  TTWLEDARQHSNSNMVIMLIGNKSDLESRREVKKEEGEAFAREHGLIFMETSAKTASNVE 157
             W  D  +    N+ I+L GNK D++ R+   K +   F R+  L + + SAK+  N E
Sbjct: 576 PNWHRDLVRVC-ENIPIVLCGNKVDIKDRKV--KAKAIVFHRKKNLQYYDISAKSNYNFE 746

Query: 158 EAFINTAKEI 167
           + F+  A+++
Sbjct: 747 KPFLWLARKL 776

 Score = 25.0 bits (53), Expect(2) = 1e-16,   Method: Compositional matrix adjust.
 Identities = 9/23 (39%), Positives = 14/23 (60%)
 Frame = +1

Query: 1   MAYAYLFKYIIIGDTGVGKSCLL 23
           M     FK +++GD GVGK+  +
Sbjct: 286 MEQEPTFKLVLVGDGGVGKTTFV 354
>19006
          Length = 568

 Score = 81.3 bits (199), Expect = 3e-16,   Method: Compositional matrix adjust.
 Identities = 43/126 (34%), Positives = 69/126 (54%), Gaps = 1/126 (0%)
 Frame = -2

Query: 8   KYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIWDTAGQES 67
           K +I+GD   GK+CLL+ F+  +F  V+  T+   + A  I +D KQ++L +WDTAGQE 
Sbjct: 432 KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVAD-IEVDSKQVELALWDTAGQED 256

Query: 68  FRSITRSYYRGAAGALLVYDITRRDTFNHLT-TWLEDARQHSNSNMVIMLIGNKSDLESR 126
           +  +    Y      L+ + I   D+  ++   W  + R H   N+ I+L+GNK DL + 
Sbjct: 255 YDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVR-HFCPNVPIILVGNKKDLRND 79

Query: 127 REVKKE 132
              K+E
Sbjct: 78  ENTKRE 61
>29380
          Length = 853

 Score = 77.4 bits (189), Expect = 3e-15,   Method: Compositional matrix adjust.
 Identities = 38/97 (39%), Positives = 64/97 (65%), Gaps = 1/97 (1%)
 Frame = -2

Query: 79  AAGALLVYDITRRDTFNHLTTWLEDARQHSNSNMVIMLIGNKSDLESR-REVKKEEGEAF 137
           A+ A++VYD+   DTF+    W+++ RQ +  +++I+L GNK DL ++ R V  E+ ++F
Sbjct: 852 ASAAIIVYDVNIADTFSRALAWVKELRQQNTESVLIILAGNKVDLATQHRAVSFEDAQSF 673

Query: 138 AREHGLIFMETSAKTASNVEEAFINTAKEIYEKIQEG 174
           ARE+GL+F E SAKT   V E F+  A ++ ++  +G
Sbjct: 672 ARENGLLFAEVSAKTGMAVNEIFMTLANQLIQQEIDG 562
>34597
          Length = 773

 Score = 75.1 bits (183), Expect(2) = 4e-15,   Method: Compositional matrix adjust.
 Identities = 35/80 (43%), Positives = 53/80 (66%)
 Frame = -2

Query: 91  RDTFNHLTTWLEDARQHSNSNMVIMLIGNKSDLESRREVKKEEGEAFAREHGLIFMETSA 150
           + +F ++  WL +  +H+N ++  M++GNK D+  +R V KE GEA AREH + FMETSA
Sbjct: 715 KKSFENIVKWLRNIDEHANEDVEKMILGNKCDMTDKRVVSKERGEAIAREHSIRFMETSA 536

Query: 151 KTASNVEEAFINTAKEIYEK 170
           K+  N+E AF   A+ I +K
Sbjct: 535 KSNINIERAFCELAEAILDK 476

 Score = 22.3 bits (46), Expect(2) = 4e-15,   Method: Compositional matrix adjust.
 Identities = 9/12 (75%), Positives = 10/12 (83%)
 Frame = -3

Query: 74  SYYRGAAGALLV 85
           SYYRGA G +LV
Sbjct: 768 SYYRGAMGIMLV 733
>12339
          Length = 578

 Score = 72.8 bits (177), Expect = 9e-14,   Method: Compositional matrix adjust.
 Identities = 45/128 (35%), Positives = 69/128 (53%), Gaps = 4/128 (3%)
 Frame = -2

Query: 65  QESFRSITRSYYRGAAGALLVYDITRRDTFNHLTTW----LEDARQHSNSNMVIMLIGNK 120
           QE F+S+  ++YRGA   +LVYD+T   TF+ L +W    L  A      +   ++IGNK
Sbjct: 577 QERFQSLGVAFYRGADCCILVYDVTEXKTFDSLDSWQREFLNQASPRDPEHFPFVVIGNK 398

Query: 121 SDLESRREVKKEEGEAFAREHGLIFMETSAKTASNVEEAFINTAKEIYEKIQEGVFDINN 180
            DL++R    K      + + G+ + ETSAK A NVE+AF   AK      QE   +I++
Sbjct: 397 IDLDNRVVTAKRGQGWCSTKGGIPYFETSAKEAINVEQAFQTVAKNAL--AQESEVEIDD 224

Query: 181 EANGIKIG 188
             + I++ 
Sbjct: 223 FPSEIRLS 200
>35581
          Length = 364

 Score = 71.2 bits (173), Expect = 3e-13,   Method: Compositional matrix adjust.
 Identities = 35/83 (42%), Positives = 48/83 (57%), Gaps = 2/83 (2%)
 Frame = +2

Query: 7   FKYIIIGDTGVGKSCLLLQFTDKRF--QPVHDLTIGVEFGARMITIDGKQIKLQIWDTAG 64
           FK +++GD GVGK+CLL +    +F   P+  LT         +T  G    + +WDTAG
Sbjct: 47  FKCVLLGDAGVGKTCLLNRLATDKFLDSPLTSLTTASLLTTVTLT-SGVMASVDLWDTAG 223

Query: 65  QESFRSITRSYYRGAAGALLVYD 87
           QE +RS+T SYYR     L+VYD
Sbjct: 224 QERYRSLTSSYYRDTKAVLIVYD 292
>26536
          Length = 829

 Score = 70.5 bits (171), Expect = 5e-13,   Method: Compositional matrix adjust.
 Identities = 40/118 (33%), Positives = 62/118 (52%), Gaps = 3/118 (2%)
 Frame = +2

Query: 53  KQIKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRDTFNH---LTTWLEDARQHSN 109
           +++     DTAGQE + S+   Y R   G ++VY +T   +F     +  WL   R    
Sbjct: 122 RRVSWTFLDTAGQEEYSSMREHYTRSGDGFIVVYSVTDVTSFQEAEAVFRWL--TRFQDE 295

Query: 110 SNMVIMLIGNKSDLESRREVKKEEGEAFAREHGLIFMETSAKTASNVEEAFINTAKEI 167
           +++  +L GNK+DL S R+V  EEG   A   G+++ ETSAKT  NV + +    + I
Sbjct: 296 TSIHAVLCGNKTDLTSDRKVTPEEGRKMADRLGMLYFETSAKTGDNVSQVYHGLLRSI 469
>00858
          Length = 1658

 Score = 69.7 bits (169), Expect = 7e-13,   Method: Compositional matrix adjust.
 Identities = 47/150 (31%), Positives = 77/150 (51%), Gaps = 1/150 (0%)
 Frame = -2

Query: 19   KSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIWDTAGQESFRSITRSYYRG 78
            KS L +Q     F   +D T   +   + + IDG+   L I DTAGQE   ++     R 
Sbjct: 1552 KSALTIQLXQNHFVEEYDPTXE-DSXRKQVVIDGETCLLDILDTAGQEEXSAMRDQCMRT 1376

Query: 79   AAGALLVYDITRRDTFNHLTTWLEDARQHSNSNMVIM-LIGNKSDLESRREVKKEEGEAF 137
              G L V+ +    +F  +  + E  ++  +++ V M L+GNK DL   R V++ +G+  
Sbjct: 1375 GEGFLCVFAVXNLKSFEDINQYREQIKRVKDADEVPMVLVGNKVDLPI-RNVEQRQGKHM 1199

Query: 138  AREHGLIFMETSAKTASNVEEAFINTAKEI 167
            A  + + ++ETSAKT   V++AF    +EI
Sbjct: 1198 AELYHIPYVETSAKTRQGVDDAFYTLVREI 1109
>11728
          Length = 635

 Score = 69.7 bits (169), Expect = 8e-13,   Method: Compositional matrix adjust.
 Identities = 45/160 (28%), Positives = 76/160 (47%), Gaps = 14/160 (8%)
 Frame = -1

Query: 7   FKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIWDTAGQE 66
            K +++GD  VGK+CLL+ +T   F   +  T+   + A ++ +D K I L +WDTAGQE
Sbjct: 488 IKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVM-VDSKPINLGLWDTAGQE 312

Query: 67  SFRSITRSYYRGAAGALLVYDITRRDTFNHL-TTWLEDARQHSNSNMVIMLIGNKSDLES 125
            +  +    Y      L+ + +    +F ++   W  +   H   N  I+L+G K DL  
Sbjct: 311 DYDRLRPLSYPQTDVFLICFSLISPASFENVKAKWYPEVSHHC-PNTPIILVGTKLDLRE 135

Query: 126 RRE------------VKKEEGEAFAREHGL-IFMETSAKT 152
            +E            +   +G A A++ G   ++E SA T
Sbjct: 134 DKETIEKLKEKKLAPITYPQGLAMAKDIGAGKYLECSALT 15
>27191
          Length = 443

 Score = 68.2 bits (165), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 24/102 (23%), Positives = 59/102 (57%)
 Frame = +1

Query: 19  KSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIWDTAGQESFRSITRSYYRG 78
           K+CL+  F + +F   +  T+GV++G ++ T++G  +++ +WD +G   +  +    Y G
Sbjct: 1   KTCLIKHFCESKFNQGYQPTVGVDYGFKIQTVNGVDMRVHMWDLSGSNEYLDVRNELYTG 180

Query: 79  AAGALLVYDITRRDTFNHLTTWLEDARQHSNSNMVIMLIGNK 120
           +    +V+D++   +F  L +WL +  + +  + + +++GN+
Sbjct: 181 SDAIFIVFDVSNTPSFEALDSWLREINRFATGSPLNVIVGNR 306
>13745
          Length = 1045

 Score = 67.8 bits (164), Expect = 4e-12,   Method: Compositional matrix adjust.
 Identities = 40/131 (30%), Positives = 72/131 (54%), Gaps = 4/131 (3%)
 Frame = +2

Query: 65  QESFRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLED----ARQHSNSNMVIMLIGNK 120
           QE F+S+  ++YRGA   +LVYD+T  ++F +L +W ++    A      +   +++GNK
Sbjct: 2   QERFQSLGVAFYRGADCCVLVYDVTAPNSFKNLDSWRDEFLIQASPRDPEHFPFVVLGNK 181

Query: 121 SDLESRREVKKEEGEAFAREHGLIFMETSAKTASNVEEAFINTAKEIYEKIQEGVFDINN 180
            DL++R+   +   +    ++ + + ETSAK   NVE AF   AK   E+  E    IN+
Sbjct: 182 VDLDNRQVSTRRAQQWCQSKNDIPYYETSAKEGINVEMAFQTIAKNALEQETEAEL-IND 358

Query: 181 EANGIKIGPQH 191
             + I++  ++
Sbjct: 359 FPDQIRLNSEN 391
>14119
          Length = 602

 Score = 66.6 bits (161), Expect = 6e-12,   Method: Compositional matrix adjust.
 Identities = 33/83 (39%), Positives = 51/83 (61%), Gaps = 1/83 (1%)
 Frame = +1

Query: 93  TFNHLTTWLEDARQHSNSNMVIMLIGNKSDLESR-REVKKEEGEAFAREHGLIFMETSAK 151
           TFN    W+++ RQ +  +++I+L GNK+DL S  R V  ++   FA ++GLIF E SAK
Sbjct: 1   TFNRALAWVKELRQQNAGSVLIVLAGNKADLASEHRAVSADDARTFAEDNGLIFAEVSAK 180

Query: 152 TASNVEEAFINTAKEIYEKIQEG 174
           T   V E F+  A ++  + +EG
Sbjct: 181 TGMAVSEVFMTIAHKLVRRAEEG 249
>19656
          Length = 428

 Score = 60.5 bits (145), Expect = 6e-10,   Method: Compositional matrix adjust.
 Identities = 29/101 (28%), Positives = 52/101 (51%), Gaps = 1/101 (0%)
 Frame = +3

Query: 8   KYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIWDTAGQES 67
           K +++GD  VGK+CLL+ +T   F   +  T+   + A ++ +DG+ + L +WDTAGQE 
Sbjct: 117 KCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVM-VDGRPVNLGLWDTAGQED 293

Query: 68  FRSITRSYYRGAAGALLVYDITRRDTFNHL-TTWLEDARQH 107
           +  +    Y      LL + +    +F ++   W  +   H
Sbjct: 294 YDRLRPLSYPQTDVFLLCFSVASPASFENIRAKWYPEVNHH 416
>09204
          Length = 1051

 Score = 59.3 bits (142), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 32/103 (31%), Positives = 55/103 (53%), Gaps = 4/103 (3%)
 Frame = -3

Query: 68   FRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLEDARQHSNSNMVIMLIGNKSDL---- 123
            + +++R YYRGA  A+L +D+T + +F+ +  W+ + RQH      + + G K DL    
Sbjct: 1046 YEAMSRIYYRGAKAAILCFDLTDKSSFDRIRFWIGELRQH-EEECKLYICGTKFDLVHDD 870

Query: 124  ESRREVKKEEGEAFAREHGLIFMETSAKTASNVEEAFINTAKE 166
              RR V +   +A A +      ETS+ T  N+E+ F   A++
Sbjct: 869  PERRAVPRSVAKALADDCMAEIYETSSMTGDNIEKLFTKIAED 741
>34359
          Length = 1042

 Score = 58.5 bits (140), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 35/122 (28%), Positives = 59/122 (48%)
 Frame = +3

Query: 38  TIGVEFGARMITIDGKQIKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRDTFNHL 97
           T+GVE            ++  +WDTAGQE F  +   YY     A++++D+T R T+ ++
Sbjct: 144 TLGVEVHPLQFNTSRGLLRFNVWDTAGQEKFGGLRDGYYIQGTCAIIMFDVTSRVTYKNV 323

Query: 98  TTWLEDARQHSNSNMVIMLIGNKSDLESRREVKKEEGEAFAREHGLIFMETSAKTASNVE 157
             W  D  +    N+ I+L GNK D++ R+   K +   F R+        +  T ++V 
Sbjct: 324 PNWHRDLVRVC-ENIPIVLCGNKVDIKDRKV--KAKAIVFHRKR-------TCSTTTSVP 473

Query: 158 EA 159
            A
Sbjct: 474 RA 479
>25618
          Length = 475

 Score = 55.8 bits (133), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 29/71 (40%), Positives = 44/71 (61%), Gaps = 1/71 (1%)
 Frame = +3

Query: 105 RQHSNSNMVIMLIGNKSDLESR-REVKKEEGEAFAREHGLIFMETSAKTASNVEEAFINT 163
           RQ +  +++I+L GNK+DL S  R V  ++   FA ++GLIF E SAKT   V E F+  
Sbjct: 57  RQQNAGSVLIVLAGNKADLASEHRAVSADDARTFAEDNGLIFAEVSAKTGMAVSEVFMTI 236

Query: 164 AKEIYEKIQEG 174
           A ++  + +EG
Sbjct: 237 AHKLVRRAEEG 269
>14775
          Length = 380

 Score = 55.5 bits (132), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 44/149 (29%), Positives = 60/149 (40%), Gaps = 3/149 (2%)
 Frame = -2

Query: 19  KSCLLLQFTDKRFQPVHDLTIGV---EFGARMITIDGKQIKLQIWDTAGQESFRSITRSY 75
           K+CLL ++    F      TI V   EF       D   ++  +WDT G E++RS+  S+
Sbjct: 379 KTCLLRRYQKGFFMDRTMPTIAVLCSEFNESRT--DPLNVRYTLWDTGGAETYRSLWVSH 206

Query: 76  YRGAAGALLVYDITRRDTFNHLTTWLEDARQHSNSNMVIMLIGNKSDLESRREVKKEEGE 135
           +RGA  ALLVYD+T                                          E G+
Sbjct: 205 FRGAQVALLVYDVT-----------------------------------------CERGQ 149

Query: 136 AFAREHGLIFMETSAKTASNVEEAFINTA 164
           AFA + G  F ETS+ T  NV+  F   A
Sbjct: 148 AFATQCGYTFFETSSVTGKNVDAVFWEIA 62
>10862
          Length = 2896

 Score = 45.8 bits (107), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 28/119 (23%), Positives = 50/119 (42%), Gaps = 11/119 (9%)
 Frame = -3

Query: 53   KQIKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLEDARQHSN--- 109
            ++ +  +WD  GQ+  R + R YY G  G + V D   RD        +++ARQ  +   
Sbjct: 2492 QECQFNVWDVGGQDKIRPLWRHYYTGTQGLIFVVDCADRDR-------IDEARQELHRII 2334

Query: 110  -----SNMVIMLIGNKSDLES---RREVKKEEGEAFAREHGLIFMETSAKTASNVEEAF 160
                  + +I++  NK DL       E++++ G    R+       + A T   + E  
Sbjct: 2333 NDREMRDAIILIFANKQDLPDAMKPHEIQEKLGLTRLRDRNWYVQPSCATTGDGLCEGL 2157
>31291
          Length = 446

 Score = 45.1 bits (105), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 32/123 (26%), Positives = 55/123 (44%), Gaps = 14/123 (11%)
 Frame = -1

Query: 57  LQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRDTFNHL-TTWLEDARQHSNSNMVIM 115
           LQ+WDTAGQE +  +    Y      +L + +    +  ++   W  + R H + ++ I+
Sbjct: 446 LQLWDTAGQEDYDRLRPLAYPNTDVFMLXFSLMSEASMKNVKVKWYPEIRHH-DPHVPIV 270

Query: 116 LIGNKSDLESRRE------------VKKEEGEAFARE-HGLIFMETSAKTASNVEEAFIN 162
           L+G K DL   +E            V   +G   A+      + E S+KT  N++ AF  
Sbjct: 269 LVGTKLDLRQDKEAVRKLRSSRQDPVSSNQGNDLAKAIKAKRYFECSSKTQENLKTAFEE 90

Query: 163 TAK 165
           T +
Sbjct: 89  TVR 81
>00552
          Length = 455

 Score = 44.3 bits (103), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 21/53 (39%), Positives = 32/53 (60%)
 Frame = -1

Query: 6   LFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQ 58
           L K +++GD GVGKS L+ +F   +F      TIGVEF  + + +DG+   +Q
Sbjct: 446 LLKVVLLGDGGVGKSSLMNRFVSNKFDAQSFHTIGVEFLTKDVVVDGETFTMQ 288

 Score = 41.6 bits (96), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 16/45 (35%), Positives = 26/45 (57%)
 Frame = -3

Query: 59  IWDTAGQESFRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLED 103
           IWDTAGQE ++S+   +YRG    LL + +    +   L+ W ++
Sbjct: 147 IWDTAGQERYKSLRTPFYRGTDCCLLTFSVDNLKSLQSLSDWYDE 13
>33605
          Length = 888

 Score = 44.3 bits (103), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 24/84 (28%), Positives = 41/84 (48%)
 Frame = +1

Query: 8   KYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIWDTAGQES 67
           + +++G    GK+ +L +F  +        TI    G  + T++ +  KL +WD  GQ+S
Sbjct: 502 RLLMLGLDNAGKTTILKKFNGEDID-----TISPTLGFNIKTLEHRGFKLNVWDVGGQQS 666

Query: 68  FRSITRSYYRGAAGALLVYDITRR 91
            RS  R+Y+    G + V D   R
Sbjct: 667 LRSYWRNYFESTDGLVWVVDSADR 738
>08153
          Length = 1703

 Score = 44.3 bits (103), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 29/121 (23%), Positives = 54/121 (44%), Gaps = 3/121 (2%)
 Frame = +1

Query: 8   KYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIWDTAGQES 67
           + +++G    GK+ +L +           +T     G  + T++ K I   +WD  GQ+ 
Sbjct: 88  RILMVGLDAAGKTTILYKLKLGEI-----VTTIPTIGFNVETVEYKNISFTVWDVGGQDK 252

Query: 68  FRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLEDARQHSNSNM---VIMLIGNKSDLE 124
            R + R Y++   G + V D   R+  N      E AR  +  ++   +I++  NK DL 
Sbjct: 253 IRPLWRHYFQNTQGLIFVVDSNDRERINEAKE--ELARMLNEDDLRDAIILVFANKQDLP 426

Query: 125 S 125
           +
Sbjct: 427 N 429
>18509
          Length = 625

 Score = 42.0 bits (97), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 26/81 (32%), Positives = 45/81 (55%), Gaps = 2/81 (2%)
 Frame = -3

Query: 96  HLTTWLEDARQHSNSNMVIMLIGNKSDLESRREVKKEEGEAFAREHGLIFMETSAKTASN 155
           H      D R      + ++L+GNK DL  R  V++ +G+  A  + + ++ETSAKT   
Sbjct: 575 HQPVQRTD*RVKDADEVPMVLVGNKVDLPIR-NVEQRQGKHMAELYHIPYVETSAKTRQG 399

Query: 156 VEEAFINTAKEI--YEKIQEG 174
           V++AF    +EI  Y++ ++G
Sbjct: 398 VDDAFYTLVREIRKYKERKDG 336
>25796
          Length = 422

 Score = 38.9 bits (89), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 16/24 (66%), Positives = 18/24 (75%)
 Frame = -1

Query: 3  YAYLFKYIIIGDTGVGKSCLLLQF 26
          Y YLFK++IIG  G GKSCLL  F
Sbjct: 77 YDYLFKFLIIGSAGSGKSCLLHHF 6
>31932
          Length = 437

 Score = 38.1 bits (87), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 27/89 (30%), Positives = 45/89 (50%), Gaps = 3/89 (3%)
 Frame = -1

Query: 100 WLEDARQHSNSNMVIMLIGNKSDLESRREVKKEEGEAFAREHGLI-FMETSAKTASNVEE 158
           W         S +  +L+GNKSDL   REV+++E E   +EH  + + ETS K  + ++E
Sbjct: 437 WTASVNWPYGSTVPCLLLGNKSDL-GHREVEQDEIEDLCKEHDFLGWSETSVKDGTMIDE 261

Query: 159 AFINTAKEIYEKIQ--EGVFDINNEANGI 185
           +     +E+  K    EG  +   + NG+
Sbjct: 260 SMNYLIEEMMAKHAELEGFSESVTQGNGV 174
>09827
          Length = 1201

 Score = 38.1 bits (87), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 34/161 (21%), Positives = 63/161 (39%), Gaps = 7/161 (4%)
 Frame = -3

Query: 7    FKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIWDTAGQE 66
             + +++G    GK+ +L +           +T     G  + T++ K I   +WD  GQ+
Sbjct: 1112 MRILMVGLDAAGKTTILYKLKLGEI-----VTTIPTIGFNVETVEYKNISFTVWDVGGQD 948

Query: 67   SFRSITRSYYRGAAGALLVYDITRRDTFN----HLTTWLEDARQHSNSNMVIMLIGNKSD 122
              R + R Y++   G + V D   ++        LT  L +       + V+++  NK D
Sbjct: 947  KIRPLWRHYFQNTQGLIFVVDSNDKERVQEAREELTRMLNEDELR---DAVLLVFANKQD 777

Query: 123  LE---SRREVKKEEGEAFAREHGLIFMETSAKTASNVEEAF 160
            L    +  E+ ++ G    R        T A T   + E  
Sbjct: 776  LPHAMATAEITEKLGLHGLRNRTWYIQSTCATTGDGLYEGL 654
>10708
          Length = 2775

 Score = 33.5 bits (75), Expect = 0.066,   Method: Compositional matrix adjust.
 Identities = 13/46 (28%), Positives = 24/46 (52%)
 Frame = -2

Query: 53   KQIKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRDTFNHLT 98
            +Q++L +WDTAGQE +  +    Y      L+ + I   D+  ++ 
Sbjct: 2729 QQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIP 2592
>33890
          Length = 220

 Score = 28.5 bits (62), Expect = 1.9,   Method: Compositional matrix adjust.
 Identities = 14/37 (37%), Positives = 20/37 (54%)
 Frame = +3

Query: 70  SITRSYYRGAAGALLVYDITRRDTFNHLTTWLEDARQ 106
           S+ RS   G    L +YD+T  +T+ HL+  LE   Q
Sbjct: 75  SVVRSKPNGCFLCLSIYDVTAFETW*HLSVKLEKVSQ 185
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|37674218|ref|NP_932771.1| exocyst complex component 8
[Mus musculus]
         (716 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

26539                                                                 156   2e-38
26881                                                                  34   0.16 
05474                                                                  33   0.36 
>26539
          Length = 400

 Score =  156 bits (395), Expect = 2e-38,   Method: Compositional matrix adjust.
 Identities = 76/133 (57%), Positives = 98/133 (73%)
 Frame = -2

Query: 398 GPKATRRAVSQLIRLGQCTKACELFLRNRAAAVHTAIRQLRIEGATLLYIHKLCHVFFTS 457
           GP+A R AV+QLIRLG+  +AC+LFL+NR+A +   IRQL+ EGAT LYI  LC VFFTS
Sbjct: 399 GPRAARHAVTQLIRLGKSAQACDLFLKNRSAVIRYNIRQLKFEGATTLYIRCLCDVFFTS 220

Query: 458 LLETAREFETDFAGTDSGCYSAFVVWARSAMGMFVDAFSKQVFDSKESLSTAAECVKVAK 517
           L +TA EF   F     GCYSAFV+WA+  +  FV  F +QVF+SK SL+T AECV +AK
Sbjct: 219 LSDTANEFLRAFPD-HYGCYSAFVIWAKHELESFVSIFRRQVFESKASLTTIAECVHLAK 43

Query: 518 EHCQQLGEIGLDL 530
           +HC +L ++G+DL
Sbjct: 42  KHCTELSKMGVDL 4
>26881
          Length = 448

 Score = 34.3 bits (77), Expect = 0.16,   Method: Compositional matrix adjust.
 Identities = 18/69 (26%), Positives = 37/69 (53%)
 Frame = +2

Query: 197 FLMNDCLLVATWLPQRRGMYRYNALYPLDRLAVVNVKDNPPMKDMFKLLMFPESRIFQAE 256
           FL ND L+    +  ++  Y    + PL+ + + NV D+  +++ +K++   +S +  A 
Sbjct: 191 FLFNDILVYGNIIMHKK-KYNKQHILPLENIKLENVDDDGNLRNGWKVMNPSKSFVVYAA 367

Query: 257 NAKIKREWL 265
            A  K+EW+
Sbjct: 368 TATEKKEWM 394
>05474
          Length = 1214

 Score = 33.1 bits (74), Expect = 0.36,   Method: Compositional matrix adjust.
 Identities = 19/69 (27%), Positives = 37/69 (53%)
 Frame = +1

Query: 197 FLMNDCLLVATWLPQRRGMYRYNALYPLDRLAVVNVKDNPPMKDMFKLLMFPESRIFQAE 256
           FL ND +LV   +   +  Y    + PL+ + + NV+D   +++ +KL+   +S +  A 
Sbjct: 67  FLFND-ILVYGNIVMHKKKYNKQHILPLENIKLENVEDEGSLRNGWKLISPSKSFVVFAA 243

Query: 257 NAKIKREWL 265
            A  K++W+
Sbjct: 244 TATEKQQWM 270
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6678059|ref|NP_033255.1| syntrophin, basic 2 [Mus
musculus]
         (520 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

01978                                                                 156   2e-38
20073                                                                  64   2e-10
38751                                                                  51   1e-06
08480                                                                  51   1e-06
29705                                                                  44   2e-04
21529                                                                  36   0.031
03831                                                                  36   0.032
24569                                                                  36   0.045
00260                                                                  33   0.24 
02951                                                                  33   0.32 
01502                                                                  33   0.38 
26154                                                                  32   0.80 
>01978
          Length = 946

 Score =  156 bits (394), Expect = 2e-38,   Method: Compositional matrix adjust.
 Identities = 76/153 (49%), Positives = 106/153 (69%), Gaps = 10/153 (6%)
 Frame = -2

Query: 377 GSDLTFATRTGSRQGIEMHLFRVETHRDLSTWTRILVQGCHAAAELIKEVSLGCTLSGQE 436
           G  L+F TRTG+R G+E H+FRVET RDL+ W+R LVQG H A   +KEV+       ++
Sbjct: 897 GDVLSFGTRTGTRHGVETHIFRVETQRDLAFWSRALVQGSHGAVATVKEVTCSVKWKDRK 718

Query: 437 VRFTVHYEHGFTITR----------DNGGASSILYRYPFERLKMSADDGIRNLYLDFGGP 486
            R  VHY+ GFT+T           D     ++L+++P+E+L+MSADDG R L+LDF   
Sbjct: 717 CRLLVHYDTGFTLTEEREEREGGSGDQRPPPTLLWQHPYEQLRMSADDGHRLLWLDFTD- 541

Query: 487 EGELTMDLHSCPKPIVFVLHTFLSAKVTRMGLL 519
           +GE  +DL++CPKPIVF++HTFLSAKV+R+GL+
Sbjct: 540 DGEQELDLNTCPKPIVFIIHTFLSAKVSRLGLI 442
>20073
          Length = 582

 Score = 63.9 bits (154), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 35/80 (43%), Positives = 48/80 (60%)
 Frame = +3

Query: 105 GLGISIKGGRENRMPILISKIFPGLAADQSRALRLGDAILSVNGTDLRQATHDQAVQALK 164
           GLG ++ GG+E   PI IS+I PG  AD+   L+ GD +LSVNG  +    H++AV+ LK
Sbjct: 3   GLGFNVMGGKEQSSPIYISRIIPGGVADRLNCLKRGDQLLSVNGVSVEGEYHEKAVELLK 182

Query: 165 RAGKEVLLEVKFIREVTPYI 184
            A   V L V++    TP I
Sbjct: 183 LAQGSVRLVVRY----TPQI 230
>38751
          Length = 329

 Score = 50.8 bits (120), Expect = 1e-06,   Method: Composition-based stats.
 Identities = 26/59 (44%), Positives = 36/59 (61%)
 Frame = +3

Query: 108 ISIKGGRENRMPILISKIFPGLAADQSRALRLGDAILSVNGTDLRQATHDQAVQALKRA 166
           + IKGG+E   PI++  I  G  A+Q + L +GD IL VNGTD    TH +AV  ++ A
Sbjct: 3   VGIKGGKEYGTPIVVYVIEEGCQAEQ-QGLNIGDRILDVNGTDFTHLTHAEAVTIMRNA 176
>08480
          Length = 698

 Score = 50.8 bits (120), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 30/63 (47%), Positives = 39/63 (61%)
 Frame = -1

Query: 131 ADQSRALRLGDAILSVNGTDLRQATHDQAVQALKRAGKEVLLEVKFIREVTPYIKKPSLV 190
           AD S  LR GD ILSVN  D+ +ATH+QA QALKRAG  V +  ++  E   Y +  + +
Sbjct: 692 ADLSGDLRRGDKILSVNDVDVERATHEQAAQALKRAGDTVEIIAQYKPE--DYNRFEAKI 519

Query: 191 SDL 193
            DL
Sbjct: 518 QDL 510
>29705
          Length = 674

 Score = 43.5 bits (101), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 26/74 (35%), Positives = 40/74 (54%)
 Frame = -1

Query: 120 ILISKIFPGLAADQSRALRLGDAILSVNGTDLRQATHDQAVQALKRAGKEVLLEVKFIRE 179
           I I+K+  G +A+Q   + + D +L+VN  +L   TH++AV ALK  G  V L       
Sbjct: 359 IFITKVIEGGSAEQDGRIAVMDRLLAVNEHNLEDVTHEEAVAALKSTGDVVRL------- 201

Query: 180 VTPYIKKPSLVSDL 193
               I KP+ ++DL
Sbjct: 200 ---TIAKPTYIADL 168

 Score = 43.5 bits (101), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 26/65 (40%), Positives = 35/65 (53%)
 Frame = -2

Query: 126 FPGLAADQSRALRLGDAILSVNGTDLRQATHDQAVQALKRAGKEVLLEVKFIREVTPYIK 185
           + G AA +   LRL D I+ V   D+   TH  AV ALKR+G  V L+VK ++  T  + 
Sbjct: 628 YRGGAAAEDGRLRLNDIIVKVGTEDVSNTTHTAAVDALKRSGNRVYLQVKRLKIPTEKVI 449

Query: 186 KPSLV 190
              LV
Sbjct: 448 DIDLV 434
>21529
          Length = 388

 Score = 36.2 bits (82), Expect = 0.031,   Method: Composition-based stats.
 Identities = 24/70 (34%), Positives = 39/70 (55%), Gaps = 3/70 (4%)
 Frame = +2

Query: 447 FTITRDNGGASSILYRYPFERLKMSADDGIRNLYLDFGGPEGEL--TMDLH-SCPKPIVF 503
           F++T   G  S++++ Y F +L+ S+DDG   L L F   E     T +L     + ++F
Sbjct: 2   FSLTE--GSDSTMVWLYKFSQLRGSSDDGKSKLKLHFQDNETRAIETKELECQVLQSLLF 175

Query: 504 VLHTFLSAKV 513
            +H FL+AKV
Sbjct: 176 CMHAFLTAKV 205
>03831
          Length = 1143

 Score = 36.2 bits (82), Expect = 0.032,   Method: Compositional matrix adjust.
 Identities = 26/76 (34%), Positives = 37/76 (48%), Gaps = 2/76 (2%)
 Frame = +3

Query: 121 LISKIFPGLAADQSRALRLGDAILSVNGTDLRQATHDQAVQALKRAGKEVLLEVKFIREV 180
            I K+  G  A ++  L+ GD I+ VNGT++    H Q V  +K  G E  L V   +E 
Sbjct: 213 FIGKVDEGSPA-EAAGLKAGDRIVEVNGTNIGNENHQQVVGRIKAGGDETRLLV-VDQET 386

Query: 181 TPYIKKPSLV--SDLP 194
             + K+   V   DLP
Sbjct: 387 DQHYKEEKRVVRGDLP 434
>24569
          Length = 584

 Score = 35.8 bits (81), Expect = 0.045,   Method: Compositional matrix adjust.
 Identities = 15/42 (35%), Positives = 28/42 (66%)
 Frame = +2

Query: 220 TKDRKVIPLKMCFAARNLSMPDLENRLIELHSPDSRNTLILR 261
           TK+R++I +    + R+LS+  + N + ++HSPDS N  I++
Sbjct: 20  TKERQMIKI---LSPRSLSLSHIHNTVSDIHSPDSHNYFIIK 136
>00260
          Length = 2573

 Score = 33.1 bits (74), Expect = 0.24,   Method: Compositional matrix adjust.
 Identities = 20/77 (25%), Positives = 34/77 (44%)
 Frame = +3

Query: 119  PILISKIFPGLAADQSRALRLGDAILSVNGTDLRQATHDQAVQALKRAGKEVLLEVKFIR 178
            P+ +    P  A  Q   + L    ++ N   + QA+  +AV  LK   +    E   +R
Sbjct: 1416 PLRLVLCCPTFAKVQFVFVNLQSMFVAENLNTVHQASDIEAVSDLKSDVQSFGFE*DLLR 1595

Query: 179  EVTPYIKKPSLVSDLPW 195
             ++PY  +PS +   PW
Sbjct: 1596 SMSPYSFQPSELGAFPW 1646
>02951
          Length = 1076

 Score = 33.1 bits (74), Expect = 0.32,   Method: Compositional matrix adjust.
 Identities = 18/51 (35%), Positives = 30/51 (58%)
 Frame = +2

Query: 136 ALRLGDAILSVNGTDLRQATHDQAVQALKRAGKEVLLEVKFIREVTPYIKK 186
            L+L D IL +NG D    TH QAV+ ++   K+ +L++   R+  P ++K
Sbjct: 68  GLQLHDKILQLNGKDFTVVTHKQAVENIR---KKPVLKMLVYRKGVPQLQK 211
>01502
          Length = 1949

 Score = 32.7 bits (73), Expect = 0.38,   Method: Compositional matrix adjust.
 Identities = 18/50 (36%), Positives = 30/50 (60%)
 Frame = +1

Query: 137 LRLGDAILSVNGTDLRQATHDQAVQALKRAGKEVLLEVKFIREVTPYIKK 186
           L+L D IL +NG D    TH QAV+ ++   K+ +L++   R+  P ++K
Sbjct: 85  LQLHDKILQLNGKDFTVVTHKQAVENIR---KKPVLKMLVYRKGVPQLQK 225
>26154
          Length = 446

 Score = 31.6 bits (70), Expect = 0.80,   Method: Composition-based stats.
 Identities = 16/47 (34%), Positives = 28/47 (59%)
 Frame = -3

Query: 101 QEAGGLGISIKGGRENRMPILISKIFPGLAADQSRALRLGDAILSVN 147
           +  G LGI+I G  +    I+IS++  G  A ++ A+ +GD +L +N
Sbjct: 210 RHGGPLGITISGTEDPLDNIVISELTAGGLAQKTGAMHVGDRLLGIN 70
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6755973|ref|NP_035829.1| lin 7 homolog c [Mus
musculus]
         (197 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

20073                                                                 154   2e-38
08480                                                                  55   2e-08
03831                                                                  44   4e-05
38751                                                                  37   0.004
26154                                                                  34   0.046
39267                                                                  31   0.25 
37239                                                                  29   1.2  
25386                                                                  28   3.3  
13994                                                                  27   6.7  
08013                                                                  27   7.7  
>20073
          Length = 582

 Score =  154 bits (390), Expect = 2e-38,   Method: Compositional matrix adjust.
 Identities = 72/93 (77%), Positives = 87/93 (93%)
 Frame = +3

Query: 102 GLGFNIMGGKEQNSPIYISRIIPGGIADRHGGLKRGDQLLSVNGVSVEGEHHEKAVELLK 161
           GLGFN+MGGKEQ+SPIYISRIIPGG+ADR   LKRGDQLLSVNGVSVEGE+HEKAVELLK
Sbjct: 3   GLGFNVMGGKEQSSPIYISRIIPGGVADRLNCLKRGDQLLSVNGVSVEGEYHEKAVELLK 182

Query: 162 AAQGKVKLVVRYTPKVLEEMESRFEKMRSAKRR 194
            AQG V+LVVRYTP++LEEME+RFE+ ++++++
Sbjct: 183 LAQGSVRLVVRYTPQILEEMEARFERQKNSRKQ 281
>08480
          Length = 698

 Score = 54.7 bits (130), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 26/64 (40%), Positives = 40/64 (62%)
 Frame = -1

Query: 126 GIADRHGGLKRGDQLLSVNGVSVEGEHHEKAVELLKAAQGKVKLVVRYTPKVLEEMESRF 185
           G AD  G L+RGD++LSVN V VE   HE+A + LK A   V+++ +Y P+     E++ 
Sbjct: 698 GPADLSGDLRRGDKILSVNDVDVERATHEQAAQALKRAGDTVEIIAQYKPEDYNRFEAKI 519

Query: 186 EKMR 189
           + +R
Sbjct: 518 QDLR 507
>03831
          Length = 1143

 Score = 43.9 bits (102), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 27/83 (32%), Positives = 46/83 (55%), Gaps = 2/83 (2%)
 Frame = +3

Query: 91  PRVVELPKTEE--GLGFNIMGGKEQNSPIYISRIIPGGIADRHGGLKRGDQLLSVNGVSV 148
           PR+  L K  +  G GFN+   K++    YI  + P   A+  GGLK GD+++ VNG ++
Sbjct: 576 PRLCHLCKWADFDGYGFNLHAEKDKPGQ-YIGSVDPNSPAET-GGLKEGDRIIEVNGENI 749

Query: 149 EGEHHEKAVELLKAAQGKVKLVV 171
           E  +H   ++ +K+   K  ++V
Sbjct: 750 ETTNHTAVIQNIKSRGDKTSMLV 818

 Score = 40.0 bits (92), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 25/83 (30%), Positives = 48/83 (57%), Gaps = 2/83 (2%)
 Frame = +3

Query: 91  PRVVELPKTEE--GLGFNIMGGKEQNSPIYISRIIPGGIADRHGGLKRGDQLLSVNGVSV 148
           PR+  + +  +  G GFN+   K + +  +I ++  G  A+   GLK GD+++ VNG ++
Sbjct: 129 PRLCHIVRWSDFNGYGFNLHAEKGK-AGQFIGKVDEGSPAEA-AGLKAGDRIVEVNGTNI 302

Query: 149 EGEHHEKAVELLKAAQGKVKLVV 171
             E+H++ V  +KA   + +L+V
Sbjct: 303 GNENHQQVVGRIKAGGDETRLLV 371
>38751
          Length = 329

 Score = 37.4 bits (85), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 23/64 (35%), Positives = 34/64 (53%)
 Frame = +3

Query: 107 IMGGKEQNSPIYISRIIPGGIADRHGGLKRGDQLLSVNGVSVEGEHHEKAVELLKAAQGK 166
           I GGKE  +PI +  I  G  A++ G L  GD++L VNG       H +AV +++ A   
Sbjct: 9   IKGGKEYGTPIVVYVIEEGCQAEQQG-LNIGDRILDVNGTDFTHLTHAEAVTIMRNAWNV 185

Query: 167 VKLV 170
           +  V
Sbjct: 186 IMTV 197
>26154
          Length = 446

 Score = 33.9 bits (76), Expect = 0.046,   Method: Compositional matrix adjust.
 Identities = 16/42 (38%), Positives = 24/42 (57%)
 Frame = -3

Query: 103 LGFNIMGGKEQNSPIYISRIIPGGIADRHGGLKRGDQLLSVN 144
           LG  I G ++    I IS +  GG+A + G +  GD+LL +N
Sbjct: 195 LGITISGTEDPLDNIVISELTAGGLAQKTGAMHVGDRLLGIN 70

 Score = 27.3 bits (59), Expect = 4.4,   Method: Compositional matrix adjust.
 Identities = 16/47 (34%), Positives = 27/47 (57%)
 Frame = -3

Query: 126 GIADRHGGLKRGDQLLSVNGVSVEGEHHEKAVELLKAAQGKVKLVVR 172
           G A R G ++ GD+L+++N V ++    + A  LL+     VKL V+
Sbjct: 408 GSAHRCGSIQAGDKLMAINDVRLDTCTVDDATHLLELPDELVKLKVQ 268
>39267
          Length = 456

 Score = 31.2 bits (69), Expect = 0.25,   Method: Compositional matrix adjust.
 Identities = 21/62 (33%), Positives = 33/62 (53%)
 Frame = +1

Query: 102 GLGFNIMGGKEQNSPIYISRIIPGGIADRHGGLKRGDQLLSVNGVSVEGEHHEKAVELLK 161
           GLGFNI G       IY+S++   G A   G +  GD++ SV  ++ +   +E A+ +L 
Sbjct: 115 GLGFNISGNMRDG--IYVSQLHNRGPASESGKIHVGDRIQSVT-IAYDNIVYEDALTILS 285

Query: 162 AA 163
            A
Sbjct: 286 YA 291
>37239
          Length = 453

 Score = 29.3 bits (64), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 20/66 (30%), Positives = 31/66 (46%), Gaps = 1/66 (1%)
 Frame = -2

Query: 124 PGGIADRHGGLKRGDQLLSVNGVSVEGEHHEKAVELLKAAQG-KVKLVVRYTPKVLEEME 182
           P   A R   +  GD+LL +NG  + G  H  A  ++K+     VKLVV      L+ + 
Sbjct: 449 PDSPAARDARIHVGDELLEINGNLLHGRCHLNASAIVKSVTAPDVKLVVNRRADSLDRIA 270

Query: 183 SRFEKM 188
            +  +M
Sbjct: 269 IKPLRM 252
>25386
          Length = 682

 Score = 27.7 bits (60), Expect = 3.3,   Method: Compositional matrix adjust.
 Identities = 21/52 (40%), Positives = 29/52 (55%)
 Frame = +2

Query: 14  ICRAIELLEKLQRSGEVPPQKLQALQRVLQSEFCNAVREVYEHVYETVDISS 65
           ICR+  LL  L  SG+V       +  VLQSEF + +R    H++  VD+SS
Sbjct: 494 ICRSKYLLNVL--SGDV*------VSIVLQSEFAHNLRFCNMHLF*MVDLSS 625
>13994
          Length = 1090

 Score = 26.6 bits (57), Expect = 6.7,   Method: Compositional matrix adjust.
 Identities = 13/30 (43%), Positives = 19/30 (63%)
 Frame = -2

Query: 127 IADRHGGLKRGDQLLSVNGVSVEGEHHEKA 156
           ++DR GG+     LL  NGVS++   HE+A
Sbjct: 561 VSDRPGGINDLCALLVRNGVSIKEIMHERA 472
>08013
          Length = 473

 Score = 26.6 bits (57), Expect = 7.7,   Method: Compositional matrix adjust.
 Identities = 14/31 (45%), Positives = 18/31 (58%)
 Frame = +1

Query: 145 GVSVEGEHHEKAVELLKAAQGKVKLVVRYTP 175
           GVS EGE   ++   LK+ +G V L VR  P
Sbjct: 292 GVSEEGEQQGESYTRLKSNEGDVALSVRAAP 384
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|83649737|ref|NP_001032850.1| capping protein (actin
filament) muscle Z-line, beta isoform a [Mus musculus]
         (277 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

20725                                                                 155   2e-38
04062                                                                  29   2.0  
21256                                                                  29   2.4  
>20725
          Length = 917

 Score =  155 bits (392), Expect = 2e-38,   Method: Compositional matrix adjust.
 Identities = 72/106 (67%), Positives = 89/106 (83%)
 Frame = -2

Query: 164 TAHYKLTSTVMLWLQTNKSGSGTMNLGGSLTRQMEKDETVSDCSPHIANIGRLVEDMENK 223
           +AHYKLTSTVMLWLQT++ GSGTMNLGGSLTRQ+E D +V+D SPHI NIGR+VE+MENK
Sbjct: 901 SAHYKLTSTVMLWLQTSREGSGTMNLGGSLTRQIESDASVNDSSPHIVNIGRMVEEMENK 722

Query: 224 IRSTLNEIYFGKTKDIVNGLRSLDAIPDNHKFKQLQRELSQVLTQR 269
           IR+TLNEIYFGKT+DIVNGLRS+  +    K + L+ +L   L++R
Sbjct: 721 IRNTLNEIYFGKTRDIVNGLRSMTPVESKVKQEALRNDLVAALSRR 584
>04062
          Length = 1156

 Score = 29.3 bits (64), Expect = 2.0,   Method: Compositional matrix adjust.
 Identities = 13/60 (21%), Positives = 29/60 (48%), Gaps = 2/60 (3%)
 Frame = +1

Query: 121 LWDLDHGFAGVILIKKAGDGSKKIKGCWDSIHVVEVQEKSSGRTA--HYKLTSTVMLWLQ 178
           +WD+ H     + ++  G      K    ++HV+ + +   G  A   Y L++++ +WL+
Sbjct: 409 VWDVGHAVLPPLHVRGPGHHPPPAKALLQNMHVITINQDPLGAQALMLYGLSNSLSVWLK 588
>21256
          Length = 394

 Score = 28.9 bits (63), Expect = 2.4,   Method: Compositional matrix adjust.
 Identities = 15/48 (31%), Positives = 26/48 (54%), Gaps = 8/48 (16%)
 Frame = +1

Query: 38  DLLSSVDQPLKIARDKVVGKD--------YLLCDYNRDGDSYRSPWSN 77
           DL  ++  PL+++R  VVG+         Y+L  + R  D + +P+SN
Sbjct: 94  DLYGAIGNPLRVSRTVVVGRKADLVNKVLYMLSYFIRCSDVHEAPFSN 237
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31982178|ref|NP_032644.2| malate dehydrogenase 1, NAD
(soluble) [Mus musculus]
         (334 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

06101                                                                 155   3e-38
01641                                                                 124   5e-29
04012                                                                  31   0.69 
>06101
          Length = 1773

 Score =  155 bits (391), Expect = 3e-38,   Method: Compositional matrix adjust.
 Identities = 106/326 (32%), Positives = 177/326 (54%), Gaps = 13/326 (3%)
 Frame = +2

Query: 1   MSEPIRVLVTGAAGQIAYSLLYSIGNGSVFGKDQPIILVLLDITPM-MGVLDGVLMELQD 59
           MS P+ V +TGA     Y+L+ SI +G VFG +  I L L D +   +  + GV ME  D
Sbjct: 272 MSTPLHVCITGAESPACYALISSISSGEVFGPNTEINLRLFDTSXADVTRIRGVAMETLD 451

Query: 60  CALPLLQDVIATDKEEIAFKDLDVAVLVGSMPIREGMERKDLLKANVKIFKSQGTALEKY 119
               L++ +      + AF+D  V V++  +  +E       ++ N  +F +    +   
Sbjct: 452 LCDGLVRGIEVVQDTKSAFQDCSVIVVLDELTQKEDESFDMWIQRNCTVFSAYAKVINDV 631

Query: 120 AKKSVKVIVVGN-PANTNCLTASKSAPSIPKENFSCLTRLDHNRAKSQIALKLGVTADDV 178
           AKK+V+V+V GN P N N +   ++AP IP++N   L+R   NRAK+ I  +L V    V
Sbjct: 632 AKKNVRVLVAGNGPVNFNAMMMIENAPKIPRQNIVALSRGVENRAKAVIGQRLSVNTAGV 811

Query: 179 KNVIIWGNHSSTQYPDVNHAKVKLQGKE----------VGVYEALKDDSWLKGEFITTVQ 228
            ++I+WGN +   Y  ++++K ++ G +          V V E + D+ WL+ E++  VQ
Sbjct: 812 VDLIVWGNVNGKHY--IDNSKSRVHGYDGAVWGPPSYSVPVVEMVHDNKWLEKEYLEQVQ 985

Query: 229 QRGAAVIKARKLSSAMSAAKAIADHIRDIWFGTPEGEFVSMGVISDGNSYGVPDDLLYSF 288
           QR   V  A   S+A SAA+AIA  +   W G+P  +  S+ V S+G  YG+P+ L++SF
Sbjct: 986 QRQETVETALGHSTAASAARAIATMLSHWWSGSPLTQMFSLAVSSEG-WYGIPEGLVFSF 1162

Query: 289 PVVIKNK-TWKFVEGLPINDFSREKM 313
           PV +  K  W  V+ + +++ +++K+
Sbjct: 1163PVTLSPKGYWTVVQDIELSEETKQKL 1240
>01641
          Length = 647

 Score =  124 bits (311), Expect = 5e-29,   Method: Compositional matrix adjust.
 Identities = 62/89 (69%), Positives = 72/89 (80%)
 Frame = -2

Query: 226 TVQQRGAAVIKARKLSSAMSAAKAIADHIRDIWFGTPEGEFVSMGVISDGNSYGVPDDLL 285
           TVQ RGAAVIKARKLSSAMSAAKA ADH+RD WFGT   ++VSMGVISDG SY + + L+
Sbjct: 487 TVQTRGAAVIKARKLSSAMSAAKATADHMRDWWFGTEGDKWVSMGVISDG-SYDIDEGLM 311

Query: 286 YSFPVVIKNKTWKFVEGLPINDFSREKMD 314
           YSFPV I NK W  V+ L I+DF+R+KMD
Sbjct: 310 YSFPVRISNKKWTIVKDLDISDFARDKMD 224
>04012
          Length = 1683

 Score = 31.2 bits (69), Expect = 0.69,   Method: Compositional matrix adjust.
 Identities = 10/23 (43%), Positives = 15/23 (65%)
 Frame = +2

Query: 184 WGNHSSTQYPDVNHAKVKLQGKE 206
           WG H S +YPD+ H +  L+G+ 
Sbjct: 569 WGRHVSAEYPDIWHVRPFLRGRH 637
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6679583|ref|NP_033023.1| RAB11B, member RAS oncogene
family [Mus musculus]
         (218 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

08428                                                                 154   3e-38
33374                                                                 119   2e-34
34468                                                                 128   1e-30
14456                                                                 125   2e-29
05468                                                                 110   5e-25
26083                                                                 108   2e-24
33794                                                                 108   2e-24
17511                                                                 107   4e-24
07465                                                                 102   9e-23
01398                                                                  98   2e-21
32723                                                                  92   1e-19
13901                                                                  91   4e-19
01972                                                                  75   3e-18
11257                                                                  86   1e-17
33380                                                                  85   2e-17
13750                                                                  79   1e-15
19006                                                                  78   3e-15
07580                                                                  77   7e-15
01095                                                                  75   3e-14
11728                                                                  74   4e-14
30760                                                                  74   6e-14
35581                                                                  73   7e-14
34359                                                                  69   2e-12
26536                                                                  68   3e-12
19656                                                                  66   1e-11
09204                                                                  66   1e-11
00858                                                                  66   1e-11
12339                                                                  66   1e-11
34597                                                                  63   2e-11
13745                                                                  65   3e-11
00552                                                                  64   3e-11
27191                                                                  63   8e-11
14119                                                                  59   1e-09
29380                                                                  59   2e-09
25618                                                                  55   3e-08
10708                                                                  44   6e-08
24619                                                                  53   1e-07
19046                                                                  53   1e-07
14775                                                                  50   6e-07
31291                                                                  50   6e-07
09827                                                                  46   1e-05
12443                                                                  43   8e-05
08153                                                                  41   3e-04
25796                                                                  38   0.003
10862                                                                  38   0.003
31932                                                                  37   0.005
33605                                                                  37   0.009
22318                                                                  27   4.8  
11062                                                                  27   7.5  
06883                                                                  27   8.9  
31928                                                                  26   9.8  
>08428
          Length = 1109

 Score =  154 bits (389), Expect = 3e-38,   Method: Compositional matrix adjust.
 Identities = 71/160 (44%), Positives = 105/160 (65%)
 Frame = -3

Query: 13   KVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIQVDGKTIKAQIWDTAGQER 72
            KV L+GDSGVGKS+++ RF    +    +STIG  F ++S+ VDG   + QIWDTAGQE+
Sbjct: 1065 KVCLLGDSGVGKSSIVLRFVTGSYRPSQESTIGASFMSKSLVVDGAGYRFQIWDTAGQEK 886

Query: 73   YRAITSAYYRGAVGALLVYDIAKHLTYENVERWLKELRDHADSNIVIMLVGNKSDLRHLR 132
            +RA+   YYRGA  A++VYD+ +  T+++V+ W++ELR     NIV+ + GNK DL  LR
Sbjct: 885  FRALAPMYYRGAAAAVIVYDVTRPRTFKSVKSWIQELRSFGPPNIVLAIAGNKCDLEELR 706

Query: 133  AVPTDEARAFAEKNNLSFIETSALDSTNVEEAFKNILTEI 172
             V   +A+ +A   +  F ETSA+ + NVEE F  +  ++
Sbjct: 705  EVVEKDAQEYASSISAIFGETSAMTAVNVEEMFTELARQL 586
>33374
          Length = 489

 Score =  119 bits (299), Expect(2) = 2e-34,   Method: Compositional matrix adjust.
 Identities = 57/114 (50%), Positives = 80/114 (70%)
 Frame = +1

Query: 48  FATRSIQVDGKTIKAQIWDTAGQERYRAITSAYYRGAVGALLVYDIAKHLTYENVERWLK 107
           F T+++ +D  T+K +IWDTAGQERY ++   YYRGA  A++VYDI    T+   + W+K
Sbjct: 139 FLTQTVCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNQDTFGRAKTWVK 318

Query: 108 ELRDHADSNIVIMLVGNKSDLRHLRAVPTDEARAFAEKNNLSFIETSALDSTNV 161
           EL+  A  NIVI L GNK+DL + R V  +EA+A+AE+N+L F+ETSA  + NV
Sbjct: 319 ELQRQASPNIVIALAGNKADLANKRMVEFEEAQAYAEENSLLFMETSAKTAMNV 480

 Score = 43.1 bits (100), Expect(2) = 2e-34,   Method: Compositional matrix adjust.
 Identities = 20/40 (50%), Positives = 29/40 (72%)
 Frame = +2

Query: 12 FKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATR 51
          FK+VL+G+S VGKS+L+ RF + +F+   +STIG  F  R
Sbjct: 32 FKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAF*LR 151
>34468
          Length = 1502

 Score =  128 bits (322), Expect = 1e-30,   Method: Compositional matrix adjust.
 Identities = 69/185 (37%), Positives = 109/185 (58%), Gaps = 2/185 (1%)
 Frame = +1

Query: 11  LFKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIQVDGKTIKAQIWDTAGQ 70
           +FK+++IGDS VGK+ L  RF   +F  ++++TIGV+F  +SIQVD + +K Q+WDTAGQ
Sbjct: 493 IFKIIVIGDSNVGKTCLTYRFCLGKFPDKTEATIGVDFREKSIQVDSEHLKLQLWDTAGQ 672

Query: 71  ERYR-AITSAYYRGAVGALLVYDIAKHLTYENVERWLKEL-RDHADSNIVIMLVGNKSDL 128
           ER+R ++   YYR     + VYD+ K  ++EN+  W++E  R +    I  +LVGNK D+
Sbjct: 673 ERFRKSMVQHYYRNVHAVVFVYDMTKMSSFENMPAWIEECDRHNLTKYIPRILVGNKCDV 852

Query: 129 RHLRAVPTDEARAFAEKNNLSFIETSALDSTNVEEAFKNILTEIYRIVSQKQIADRAAHD 188
               AV T+ A+ FA+ +N+   ETSA D           +T  +++   K +      +
Sbjct: 853 VERIAVNTNLAQKFADAHNMPLFETSAKDDEKANHVDAIFMTVAHKLKXSKPMMPAHLSE 1032

Query: 189 ESPGN 193
             PG+
Sbjct: 1033MVPGD 1047
>14456
          Length = 1867

 Score =  125 bits (313), Expect = 2e-29,   Method: Compositional matrix adjust.
 Identities = 73/200 (36%), Positives = 113/200 (56%), Gaps = 5/200 (2%)
 Frame = -1

Query: 21   GVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIQVDGKTIKAQIWDTAGQERYRAITSAY 80
            GVGKS+L++RF  N+F+ +S  TIGVEF  + + VD +T   QIWDTAGQER++++ + +
Sbjct: 1111 GVGKSSLMNRFVSNKFDAQSFHTIGVEFLNKDVVVDDETYTMQIWDTAGQERFKSLRTPF 932

Query: 81   YRGAVGALLVYDIAKHLTYENVERWLKELRDHAD----SNIVIMLVGNKSDLRHLRAVPT 136
            YRGA   LL + +    ++ N+  W KE   +AD         +++GNK D+   R V  
Sbjct: 931  YRGADCCLLTFSVDSMQSFRNLSMWRKEFLYYADIQDGVTFPFVVLGNKIDVEG-RQVTN 755

Query: 137  DEARAFAEKN-NLSFIETSALDSTNVEEAFKNILTEIYRIVSQKQIADRAAHDESPGNNV 195
            +EAR++   N N  + ETSA D+TNVE+AF   +  +  +  Q+++  + AH      N 
Sbjct: 754  EEARSWCTANSNAPYFETSAKDATNVEKAFLAAVQRLREVEDQQEV--KTAH-----GNT 596

Query: 196  VDISVPPTTDGQRPNKLQCC 215
            VD++        R     CC
Sbjct: 595  VDLN-----RAARGKSSSCC 551
>05468
          Length = 1558

 Score =  110 bits (274), Expect = 5e-25,   Method: Compositional matrix adjust.
 Identities = 66/214 (30%), Positives = 116/214 (54%), Gaps = 7/214 (3%)
 Frame = -3

Query: 9    DYLFKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIQVDGKT-IKAQIWDT 67
            ++L+K+++IG+ G GK++++ R+    F+   ++TIGV+FA + +  D  T I+ Q+WD 
Sbjct: 1547 EHLYKILVIGELGTGKTSIIKRYVHQFFSQHYRATIGVDFALKVLNWDADTLIRLQLWDI 1368

Query: 68   AGQERYRAITSAYYRGAVGALLVYDIAKHLTYENVERWLKELRDHAD----SNIVIMLVG 123
            AGQER+  +T  YY+ AVGA +V+D+ +  T++ V +W  +L         S +  +L+ 
Sbjct: 1367 AGQERFGNMTRVYYKEAVGAFVVFDVTRASTFDAVTKWKNDLDSKVQLADGSPVPCVLLA 1188

Query: 124  NKSDLRHLRAV-PTDEARAF-AEKNNLSFIETSALDSTNVEEAFKNILTEIYRIVSQKQI 181
            NK D      V  T +   F +EK  + + ETSA ++ N++EA + ++T I         
Sbjct: 1187 NKCDQAKEGLVNNTSQMDEFCSEKGFIGWYETSAKENINIDEAARFLVTRILE------- 1029

Query: 182  ADRAAHDESPGNNVVDISVPPTTDGQRPNKLQCC 215
             DRA        +   I +   + G +  K+ CC
Sbjct: 1028 KDRAMQLGDDDRDRDRIVLDKPSSGTQERKINCC 927
>26083
          Length = 432

 Score =  108 bits (270), Expect = 2e-24,   Method: Compositional matrix adjust.
 Identities = 44/114 (38%), Positives = 82/114 (71%)
 Frame = +1

Query: 12  FKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIQVDGKTIKAQIWDTAGQE 71
           FK+V +G+  VGK++L++RF  + F+   ++TIG++F ++++ ++ +TI+ Q+WDTAGQE
Sbjct: 79  FKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTIRLQLWDTAGQE 258

Query: 72  RYRAITSAYYRGAVGALLVYDIAKHLTYENVERWLKELRDHADSNIVIMLVGNK 125
           R+R++  +Y R +  A++VYDI    ++    +W+ ++R    S+++IMLVGNK
Sbjct: 259 RFRSLIPSYIRDSSVAVVVYDITNANSFHQTSKWIDDVRTERGSDVIIMLVGNK 420
>33794
          Length = 779

 Score =  108 bits (269), Expect = 2e-24,   Method: Compositional matrix adjust.
 Identities = 58/170 (34%), Positives = 96/170 (56%), Gaps = 12/170 (7%)
 Frame = -1

Query: 46  VEFATRSIQVDGKTIKAQIWDTAGQERYRAITSAYYRGAVGALLVYDIAKHLTYENVERW 105
           V + T +I ++GK +K QIWDT+GQ R+  I  +Y RGA G +LVYDI    +++ ++RW
Sbjct: 692 VAYKTTTILLEGKRVKLQIWDTSGQGRFCTIIRSYSRGAQGIILVYDITNKWSFDGIDRW 513

Query: 106 LKELRDHADSNIVIMLVGNKSDLRHLRAVPTDEARAFAEKNNLSFIETSALDSTNVEEAF 165
           LKE+ +HA   I  +LVGN+  L + R V   +A  +A +NN+S  E S L   N+ E+F
Sbjct: 512 LKEVEEHAP-GIPKVLVGNRLHLAYKRQVAAKQAETYASRNNMSCFEISPLCDFNIRESF 336

Query: 166 ---------KNILTEIYR---IVSQKQIADRAAHDESPGNNVVDISVPPT 203
                    +N +  I+R   ++S +++  R     +    +  + +PP+
Sbjct: 335 CELARMALHRNGMEHIWRSNKVLSLQELCCRTIVRRTSVYAIDSLHLPPS 186
>17511
          Length = 483

 Score =  107 bits (266), Expect = 4e-24,   Method: Compositional matrix adjust.
 Identities = 48/122 (39%), Positives = 81/122 (66%), Gaps = 4/122 (3%)
 Frame = -3

Query: 11  LFKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIQVDGKTIKAQIWDTAGQ 70
           L KV+++GDSGVGK++L++++   +F+ + K+TIG +F T+ + VD + +  QIWDTAGQ
Sbjct: 367 LLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQIWDTAGQ 188

Query: 71  ERYRAITSAYYRGAVGALLVYDIAKHLTYENVERWLKELRDHADS----NIVIMLVGNKS 126
           ER++++  A+YRGA   +LV+D+    T+ +++ W  E    A      N   +++GNK 
Sbjct: 187 ERFQSLGVAFYRGADCCVLVFDVTMPNTFRSLDSWRDEFLIQASPRDPENFPFVVIGNKI 8

Query: 127 DL 128
           DL
Sbjct: 7   DL 2
>07465
          Length = 1103

 Score =  102 bits (255), Expect = 9e-23,   Method: Compositional matrix adjust.
 Identities = 61/183 (33%), Positives = 98/183 (53%)
 Frame = +3

Query: 25  SNLLSRFTRNEFNLESKSTIGVEFATRSIQVDGKTIKAQIWDTAGQERYRAITSAYYRGA 84
           S+++ R+ +  F  + K TIGV+F  R I+V G+ ++  +WDTAGQE + AIT AYYRGA
Sbjct: 240 SSMIQRYCKGIFTKDYKKTIGVDFLERQIEVGGEDVRLMLWDTAGQEEFDAITKAYYRGA 419

Query: 85  VGALLVYDIAKHLTYENVERWLKELRDHADSNIVIMLVGNKSDLRHLRAVPTDEARAFAE 144
              +L +      ++E +E W +++ D     I +++V NK DL     V  +EA   A+
Sbjct: 420 QACVLAFSTVDRDSFEALETWKRKVEDEV-GEIGMVIVQNKIDLIDDAVVRPEEAENLAK 596

Query: 145 KNNLSFIETSALDSTNVEEAFKNILTEIYRIVSQKQIADRAAHDESPGNNVVDISVPPTT 204
           K  L F  TS  ++ NV+E F             + +AD+  H  + G + V+++  P  
Sbjct: 597 KLRLRFYRTSVKENMNVDEVF-------------RYLADKYLHQLNTGMDEVNLT--PQK 731

Query: 205 DGQ 207
            GQ
Sbjct: 732 IGQ 740
>01398
          Length = 1421

 Score = 98.2 bits (243), Expect = 2e-21,   Method: Compositional matrix adjust.
 Identities = 49/113 (43%), Positives = 70/113 (61%), Gaps = 1/113 (0%)
 Frame = -2

Query: 70   QERYRAITSAYYRGAVGALLVYDIAKHLTYENVERWLKELRDHADSNIVIMLV-GNKSDL 128
            QER+R+IT +YYR +VG ++VYDI K  T+EN+++W +E R+H + +  I LV G+KSD 
Sbjct: 1420 QERFRSITRSYYRNSVGVIIVYDITKRSTFENLKQWYEEARNHIEPHKAIFLVLGHKSDR 1241

Query: 129  RHLRAVPTDEARAFAEKNNLSFIETSALDSTNVEEAFKNILTEIYRIVSQKQI 181
               R V   E R FAE + L F ETSA    N+E+ F  I  + Y+ +    I
Sbjct: 1240 EDARQVTAREGRRFAEMHGLKFFETSAKSGHNIEDVFAQIAKDTYQHLQDGHI 1082
>32723
          Length = 384

 Score = 92.4 bits (228), Expect = 1e-19,   Method: Compositional matrix adjust.
 Identities = 44/111 (39%), Positives = 70/111 (63%)
 Frame = +2

Query: 70  QERYRAITSAYYRGAVGALLVYDIAKHLTYENVERWLKELRDHADSNIVIMLVGNKSDLR 129
           QER+R+IT +YYR A   +LVYD+    +YE++ +W+ E+  +A + ++  LVGNK D  
Sbjct: 2   QERFRSITQSYYRSANALILVYDVCSQQSYESLPQWIHEIELYAGTKVLAFLVGNKIDQT 181

Query: 130 HLRAVPTDEARAFAEKNNLSFIETSALDSTNVEEAFKNILTEIYRIVSQKQ 180
             R +PT   + FAE+  + F+ETSA ++ NVE+ F  I    Y++ +Q Q
Sbjct: 182 DKREIPTHIGKEFAERYEMRFLETSAKEADNVEKLFSTI---AYQLTAQAQ 325
>13901
          Length = 962

 Score = 90.9 bits (224), Expect = 4e-19,   Method: Compositional matrix adjust.
 Identities = 41/96 (42%), Positives = 64/96 (66%), Gaps = 1/96 (1%)
 Frame = -3

Query: 11  LFKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIQVDGKT-IKAQIWDTAG 69
           LFKV++IGD  VGK++ + R+  + F  + K TIGV+FA + I+   K  IK Q+WD AG
Sbjct: 288 LFKVIIIGDPTVGKTSFVQRYVNDSFRRDYKMTIGVDFALKVIRWSDKCNIKLQLWDIAG 109

Query: 70  QERYRAITSAYYRGAVGALLVYDIAKHLTYENVERW 105
           QER+ ++T  YY+ A   ++++D+ +  TY+N  RW
Sbjct: 108 QERFTSMTRVYYKDAHACIVMFDLTQKNTYQNAIRW 1
>01972
          Length = 2359

 Score = 74.7 bits (182), Expect(2) = 3e-18,   Method: Compositional matrix adjust.
 Identities = 40/124 (32%), Positives = 66/124 (53%)
 Frame = +3

Query: 42  STIGVEFATRSIQVDGKTIKAQIWDTAGQERYRAITSAYYRGAVGALLVYDIAKHLTYEN 101
           +T+GVE            +K  +WDTAGQE++  +   YY     A++++D+   +TY+N
Sbjct: 393 ATLGVEVHPLLFHTSRGKLKFNVWDTAGQEKFGGLRDGYYIQGQCAVIMFDVTSRVTYKN 572

Query: 102 VERWLKELRDHADSNIVIMLVGNKSDLRHLRAVPTDEARAFAEKNNLSFIETSALDSTNV 161
           V  W ++L    + NI I+L GNK D++  +     +A  F  K NL + + SA  + N 
Sbjct: 573 VPNWHRDLVRVCE-NIPIVLCGNKVDIKDRKV--KAKAIVFHRKKNLQYYDISAKSNYNF 743

Query: 162 EEAF 165
           E+ F
Sbjct: 744 EKPF 755

 Score = 33.9 bits (76), Expect(2) = 3e-18,   Method: Compositional matrix adjust.
 Identities = 14/30 (46%), Positives = 19/30 (63%)
 Frame = +1

Query: 7   EYDYLFKVVLIGDSGVGKSNLLSRFTRNEF 36
           E +  FK+VL+GD GVGK+  + R    EF
Sbjct: 289 EQEPTFKLVLVGDGGVGKTTFVKRHVTGEF 378
>11257
          Length = 1102

 Score = 85.9 bits (211), Expect = 1e-17,   Method: Compositional matrix adjust.
 Identities = 44/133 (33%), Positives = 79/133 (59%), Gaps = 5/133 (3%)
 Frame = -2

Query: 51   RSIQVDGKTIKAQIWDTAGQERYRAITSAYYRGAVGALLVYDIAKHLTYENVERWLKELR 110
            + + VDG+T   QIWDTAGQERY+++ + +YRG    LL + +    + +++  W  E  
Sbjct: 1053 KDVVVDGETFTMQIWDTAGQERYKSLRTPFYRGTDCCLLTFSVDNLKSLQSLSDWYDEFV 874

Query: 111  DHAD----SNIVIMLVGNKSDLRHLRAVPTDEARAFAEKN-NLSFIETSALDSTNVEEAF 165
            ++AD    ++   +++GNK+D+   R V +++A  +   + NL + ETSA DS NV++AF
Sbjct: 873  NYADIQDSASFPFVIIGNKADIEE-REVSSEDAYNWCRTHGNLPYFETSAKDSLNVQQAF 697

Query: 166  KNILTEIYRIVSQ 178
              ++  +  +  Q
Sbjct: 696  LAVVRRLREMDEQ 658
>33380
          Length = 282

 Score = 85.1 bits (209), Expect = 2e-17,   Method: Compositional matrix adjust.
 Identities = 37/75 (49%), Positives = 53/75 (70%)
 Frame = +3

Query: 58  KTIKAQIWDTAGQERYRAITSAYYRGAVGALLVYDIAKHLTYENVERWLKELRDHADSNI 117
           K +K QIWDTAGQERYR IT+AYYRGA+G +L+YD+    ++  V+ W  +++ ++  N 
Sbjct: 54  KRVKLQIWDTAGQERYRTITTAYYRGAMGFILMYDVTNEESFNAVQDWCTQIKTYSWDNA 233

Query: 118 VIMLVGNKSDLRHLR 132
            ++LVGNK DL   R
Sbjct: 234 QVVLVGNKCDLEDER 278
>13750
          Length = 503

 Score = 79.3 bits (194), Expect = 1e-15,   Method: Compositional matrix adjust.
 Identities = 58/176 (32%), Positives = 90/176 (51%), Gaps = 4/176 (2%)
 Frame = -2

Query: 24  KSNLLSRFTRNEFNLESKSTIGV---EFATRSIQVDGKTIKAQIWDTAGQERYRAITSAY 80
           K+ LL R+ +  F   +  TI V   EF     + D   ++  +WDT G E YR++  ++
Sbjct: 502 KTCLLRRYQKGFFMDRTMPTIAVLCSEF--NESRTDPLNVRYTLWDTGGAETYRSLWVSH 329

Query: 81  YRGAVGALLVYDIAKHLTYENVER-WLKELRDHADSNIVIMLVGNKSDLRHLRAVPTDEA 139
           +RGA  ALLVYD+    ++      W K L  +     VI  VG+K+DL   R + T+  
Sbjct: 328 FRGAQVALLVYDVTCEWSFLTATTVWRKALMKNIPEAQVI-FVGSKTDLEENRVISTERG 152

Query: 140 RAFAEKNNLSFIETSALDSTNVEEAFKNILTEIYRIVSQKQIADRAAHDESPGNNV 195
           +AFA +   +F ETS++   NV+  F     EI  I+++ Q   R+AH E   + V
Sbjct: 151 QAFATQCGYTFFETSSVTGKNVDAVFW----EIAFILARLQ---RSAHLELSMDTV 5
>19006
          Length = 568

 Score = 78.2 bits (191), Expect = 3e-15,   Method: Compositional matrix adjust.
 Identities = 43/119 (36%), Positives = 67/119 (56%), Gaps = 1/119 (0%)
 Frame = -2

Query: 13  KVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIQVDGKTIKAQIWDTAGQER 72
           K+V++GD   GK+ LL  F++++F      T+   +    I+VD K ++  +WDTAGQE 
Sbjct: 432 KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVA-DIEVDSKQVELALWDTAGQED 256

Query: 73  YRAITSAYYRGAVGALLVYDIAKHLTYENV-ERWLKELRDHADSNIVIMLVGNKSDLRH 130
           Y  +    Y      L+ + I    + EN+ E+W  E+R H   N+ I+LVGNK DLR+
Sbjct: 255 YDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVR-HFCPNVPIILVGNKKDLRN 82
>07580
          Length = 921

 Score = 76.6 bits (187), Expect = 7e-15,   Method: Compositional matrix adjust.
 Identities = 40/123 (32%), Positives = 68/123 (55%), Gaps = 1/123 (0%)
 Frame = +3

Query: 51  RSIQVDGKTIKAQIWDTAGQERYRAITSAYYRGAVGALLVYDIAKHLTYENVERWLKE-L 109
           + ++VDG+    +I DTAG E++ A+   Y +   G LL Y I    T+ +++   ++ L
Sbjct: 177 KQVEVDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFLLAYSITAQSTFNDLQELREQIL 356

Query: 110 RDHADSNIVIMLVGNKSDLRHLRAVPTDEARAFAEKNNLSFIETSALDSTNVEEAFKNIL 169
           R     ++ ++LVGNK DL   R V  D+ +  A   + +F+ETSA    NV E F +++
Sbjct: 357 RVKDTDDVPMLLVGNKCDLEDERVVGKDQGQGLARSFSCAFLETSAKARINVNEIFMDLV 536

Query: 170 TEI 172
            +I
Sbjct: 537 RQI 545
>01095
          Length = 1745

 Score = 74.7 bits (182), Expect = 3e-14,   Method: Compositional matrix adjust.
 Identities = 38/86 (44%), Positives = 56/86 (65%)
 Frame = -1

Query: 89   LVYDIAKHLTYENVERWLKELRDHADSNIVIMLVGNKSDLRHLRAVPTDEARAFAEKNNL 148
            +VYDI    T+   + W+KEL+  A  NIVI L GNK+DL + R V  +EA+A+AE+N+L
Sbjct: 1745 VVYDITNQDTFGRAKTWVKELQRQASPNIVIALAGNKADLANKRMVEFEEAQAYAEENSL 1566

Query: 149  SFIETSALDSTNVEEAFKNILTEIYR 174
             F+ETSA  + NV + F  I  ++ +
Sbjct: 1565 LFMETSAKTAMNVNDIFLAIAKKLPK 1488
>11728
          Length = 635

 Score = 73.9 bits (180), Expect = 4e-14,   Method: Compositional matrix adjust.
 Identities = 43/119 (36%), Positives = 63/119 (52%), Gaps = 1/119 (0%)
 Frame = -1

Query: 12  FKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIQVDGKTIKAQIWDTAGQE 71
            K V++GD  VGK+ LL  +T N F  E   T+   ++  ++ VD K I   +WDTAGQE
Sbjct: 488 IKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSA-NVMVDSKPINLGLWDTAGQE 312

Query: 72  RYRAITSAYYRGAVGALLVYDIAKHLTYENVE-RWLKELRDHADSNIVIMLVGNKSDLR 129
            Y  +    Y      L+ + +    ++ENV+ +W  E+  H   N  I+LVG K DLR
Sbjct: 311 DYDRLRPLSYPQTDVFLICFSLISPASFENVKAKWYPEVSHHC-PNTPIILVGTKLDLR 138
>30760
          Length = 596

 Score = 73.6 bits (179), Expect = 6e-14,   Method: Compositional matrix adjust.
 Identities = 49/175 (28%), Positives = 86/175 (49%), Gaps = 6/175 (3%)
 Frame = -1

Query: 13  KVVLIGDSGVGKSNLLSRFTRN--EFNLESKSTIGVEFATRSIQVDGK--TIKAQIWDTA 68
           K ++ GDSGVGKS++   F  +   F      T GVE   + + +      ++  ++D+A
Sbjct: 524 KCIVTGDSGVGKSSICQVFHSDSAHFPKNYSMTTGVEVLVKLVNIPDSRDQVELYLFDSA 345

Query: 69  GQERYRAITSAYYRGAVGALLVYDIAKHLTYENVERWLKELRDHADSNIVI--MLVGNKS 126
           G+E +    + ++      ++VYD+    ++    RWL+ +R  A  N VI  +LV NK+
Sbjct: 344 GKEIFSENVTKFWDQPSVVMVVYDVTDETSFSGCVRWLERVR-AAKPNTVIPGVLVANKT 168

Query: 127 DLRHLRAVPTDEARAFAEKNNLSFIETSALDSTNVEEAFKNILTEIYRIVSQKQI 181
           DL   R V   E +  A+ + L + E SA +  N +  F   L   +  + Q+Q+
Sbjct: 167 DLDERRRVSRKEGKDLAQSHGLEYFECSAKEMQNTDTPF-FCLAHAFHKLYQEQL 6
>35581
          Length = 364

 Score = 73.2 bits (178), Expect = 7e-14,   Method: Compositional matrix adjust.
 Identities = 40/87 (45%), Positives = 53/87 (60%), Gaps = 2/87 (2%)
 Frame = +2

Query: 12  FKVVLIGDSGVGKSNLLSRFTRNEFNLESK--STIGVEFATRSIQVDGKTIKAQIWDTAG 69
           FK VL+GD+GVGK+ LL+R   ++F L+S   S       T      G      +WDTAG
Sbjct: 47  FKCVLLGDAGVGKTCLLNRLATDKF-LDSPLTSLTTASLLTTVTLTSGVMASVDLWDTAG 223

Query: 70  QERYRAITSAYYRGAVGALLVYDIAKH 96
           QERYR++TS+YYR     L+VYD A+H
Sbjct: 224 QERYRSLTSSYYRDTKAVLIVYD-AEH 301
>34359
          Length = 1042

 Score = 68.6 bits (166), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 36/118 (30%), Positives = 63/118 (53%)
 Frame = +3

Query: 12  FKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIQVDGKTIKAQIWDTAGQE 71
           FK+VL+G      +N++ R        +  +T+GVE            ++  +WDTAGQE
Sbjct: 54  FKLVLVGGRWEWANNIVKRHVTGS*K-KYVATLGVEVHPLQFNTSRGLLRFNVWDTAGQE 230

Query: 72  RYRAITSAYYRGAVGALLVYDIAKHLTYENVERWLKELRDHADSNIVIMLVGNKSDLR 129
           ++  +   YY     A++++D+   +TY+NV  W ++L    + NI I+L GNK D++
Sbjct: 231 KFGGLRDGYYIQGTCAIIMFDVTSRVTYKNVPNWHRDLVRVCE-NIPIVLCGNKVDIK 401
>26536
          Length = 829

 Score = 68.2 bits (165), Expect = 3e-12,   Method: Compositional matrix adjust.
 Identities = 38/112 (33%), Positives = 60/112 (53%), Gaps = 3/112 (2%)
 Frame = +2

Query: 66  DTAGQERYRAITSAYYRGAVGALLVYDIAKHLTYENVE---RWLKELRDHADSNIVIMLV 122
           DTAGQE Y ++   Y R   G ++VY +    +++  E   RWL   +D  +++I  +L 
Sbjct: 146 DTAGQEEYSSMREHYTRSGDGFIVVYSVTDVTSFQEAEAVFRWLTRFQD--ETSIHAVLC 319

Query: 123 GNKSDLRHLRAVPTDEARAFAEKNNLSFIETSALDSTNVEEAFKNILTEIYR 174
           GNK+DL   R V  +E R  A++  + + ETSA    NV + +  +L  I R
Sbjct: 320 GNKTDLTSDRKVTPEEGRKMADRLGMLYFETSAKTGDNVSQVYHGLLRSIPR 475

 Score = 34.3 bits (77), Expect = 0.043,   Method: Compositional matrix adjust.
 Identities = 13/25 (52%), Positives = 20/25 (80%)
 Frame = +2

Query: 12  FKVVLIGDSGVGKSNLLSRFTRNEF 36
           +K+V++G  GVGKS+L  RFT++ F
Sbjct: 488 YKIVMLGSGGVGKSSLTIRFTQDTF 562
>19656
          Length = 428

 Score = 66.2 bits (160), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 34/102 (33%), Positives = 54/102 (52%), Gaps = 1/102 (0%)
 Frame = +3

Query: 13  KVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIQVDGKTIKAQIWDTAGQER 72
           K V++GD  VGK+ LL  +T N F  E   T+   ++  ++ VDG+ +   +WDTAGQE 
Sbjct: 117 KCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSA-NVMVDGRPVNLGLWDTAGQED 293

Query: 73  YRAITSAYYRGAVGALLVYDIAKHLTYENVE-RWLKELRDHA 113
           Y  +    Y      LL + +A   ++EN+  +W  E+  H 
Sbjct: 294 YDRLRPLSYPQTDVFLLCFSVASPASFENIRAKWYPEVNHHC 419
>09204
          Length = 1051

 Score = 66.2 bits (160), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 35/101 (34%), Positives = 54/101 (53%), Gaps = 4/101 (3%)
 Frame = -3

Query: 72   RYRAITSAYYRGAVGALLVYDIAKHLTYENVERWLKELRDHADSNIVIMLVGNKSDLRH- 130
            RY A++  YYRGA  A+L +D+    +++ +  W+ ELR H +    + + G K DL H 
Sbjct: 1049 RYEAMSRIYYRGAKAAILCFDLTDKSSFDRIRFWIGELRQH-EEECKLYICGTKFDLVHD 873

Query: 131  ---LRAVPTDEARAFAEKNNLSFIETSALDSTNVEEAFKNI 168
                RAVP   A+A A+       ETS++   N+E+ F  I
Sbjct: 872  DPERRAVPRSVAKALADDCMAEIYETSSMTGDNIEKLFTKI 750
>00858
          Length = 1658

 Score = 65.9 bits (159), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 45/150 (30%), Positives = 79/150 (52%), Gaps = 1/150 (0%)
 Frame = -2

Query: 24   KSNLLSRFTRNEFNLESKSTIGVEFATRSIQVDGKTIKAQIWDTAGQERYRAITSAYYRG 83
            KS L  +  +N F +E       +   + + +DG+T    I DTAGQE   A+     R 
Sbjct: 1552 KSALTIQLXQNHF-VEEYDPTXEDSXRKQVVIDGETCLLDILDTAGQEEXSAMRDQCMRT 1376

Query: 84   AVGALLVYDIAKHLTYENVERWLKELRDHADSNIVIM-LVGNKSDLRHLRAVPTDEARAF 142
              G L V+ +    ++E++ ++ ++++   D++ V M LVGNK DL  +R V   + +  
Sbjct: 1375 GEGFLCVFAVXNLKSFEDINQYREQIKRVKDADEVPMVLVGNKVDL-PIRNVEQRQGKHM 1199

Query: 143  AEKNNLSFIETSALDSTNVEEAFKNILTEI 172
            AE  ++ ++ETSA     V++AF  ++ EI
Sbjct: 1198 AELYHIPYVETSAKTRQGVDDAFYTLVREI 1109
>12339
          Length = 578

 Score = 65.9 bits (159), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 39/131 (29%), Positives = 73/131 (55%), Gaps = 10/131 (7%)
 Frame = -2

Query: 70  QERYRAITSAYYRGAVGALLVYDIAKHLTYENVERWLKELRDHADS----NIVIMLVGNK 125
           QER++++  A+YRGA   +LVYD+ +  T+++++ W +E  + A      +   +++GNK
Sbjct: 577 QERFQSLGVAFYRGADCCILVYDVTEXKTFDSLDSWQREFLNQASPRDPEHFPFVVIGNK 398

Query: 126 SDLRHLRAVPTDEARAFAE-KNNLSFIETSALDSTNVEEAFKNILTEIYRIVSQKQIAD- 183
            DL + R V     + +   K  + + ETSA ++ NVE+AF+ +        S+ +I D 
Sbjct: 397 IDLDN-RVVTAKRGQGWCSTKGGIPYFETSAKEAINVEQAFQTVAKNALAQESEVEIDDF 221

Query: 184 ----RAAHDES 190
               R ++D+S
Sbjct: 220 PSEIRLSNDDS 188
>34597
          Length = 773

 Score = 62.8 bits (151), Expect(2) = 2e-11,   Method: Compositional matrix adjust.
 Identities = 32/105 (30%), Positives = 59/105 (56%), Gaps = 8/105 (7%)
 Frame = -2

Query: 98  TYENVERWLKELRDHADSNIVIMLVGNKSDLRHLRAVPTDEARAFAEKNNLSFIETSALD 157
           ++EN+ +WL+ + +HA+ ++  M++GNK D+   R V  +   A A ++++ F+ETSA  
Sbjct: 709 SFENIVKWLRNIDEHANEDVEKMILGNKCDMTDKRVVSKERGEAIAREHSIRFMETSAKS 530

Query: 158 STNVEEAFKNILTEIYRIVSQKQIA--------DRAAHDESPGNN 194
           + N+E AF  +   I    + ++ A        DR   D++PG N
Sbjct: 529 NINIERAFCELAEAILDKTAGRESAENPERVVIDRGNSDKAPGYN 395

 Score = 22.7 bits (47), Expect(2) = 2e-11,   Method: Compositional matrix adjust.
 Identities = 8/13 (61%), Positives = 12/13 (92%)
 Frame = -3

Query: 78  SAYYRGAVGALLV 90
           ++YYRGA+G +LV
Sbjct: 771 TSYYRGAMGIMLV 733
>13745
          Length = 1045

 Score = 64.7 bits (156), Expect = 3e-11,   Method: Compositional matrix adjust.
 Identities = 37/104 (35%), Positives = 62/104 (59%), Gaps = 5/104 (4%)
 Frame = +2

Query: 70  QERYRAITSAYYRGAVGALLVYDIAKHLTYENVERWLKELRDHADS----NIVIMLVGNK 125
           QER++++  A+YRGA   +LVYD+    +++N++ W  E    A      +   +++GNK
Sbjct: 2   QERFQSLGVAFYRGADCCVLVYDVTAPNSFKNLDSWRDEFLIQASPRDPEHFPFVVLGNK 181

Query: 126 SDLRHLRAVPTDEARAFAE-KNNLSFIETSALDSTNVEEAFKNI 168
            DL + R V T  A+ + + KN++ + ETSA +  NVE AF+ I
Sbjct: 182 VDLDN-RQVSTRRAQQWCQSKNDIPYYETSAKEGINVEMAFQTI 310
>00552
          Length = 455

 Score = 64.3 bits (155), Expect = 3e-11,   Method: Compositional matrix adjust.
 Identities = 30/53 (56%), Positives = 40/53 (75%)
 Frame = -1

Query: 11  LFKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIQVDGKTIKAQ 63
           L KVVL+GD GVGKS+L++RF  N+F+ +S  TIGVEF T+ + VDG+T   Q
Sbjct: 446 LLKVVLLGDGGVGKSSLMNRFVSNKFDAQSFHTIGVEFLTKDVVVDGETFTMQ 288

 Score = 44.3 bits (103), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 17/49 (34%), Positives = 30/49 (61%)
 Frame = -3

Query: 64  IWDTAGQERYRAITSAYYRGAVGALLVYDIAKHLTYENVERWLKELRDH 112
           IWDTAGQERY+++ + +YRG    LL + +    + +++  W  E  ++
Sbjct: 147 IWDTAGQERYKSLRTPFYRGTDCCLLTFSVDNLKSLQSLSDWYDEFVNY 1
>27191
          Length = 443

 Score = 63.2 bits (152), Expect = 8e-11,   Method: Compositional matrix adjust.
 Identities = 26/102 (25%), Positives = 58/102 (56%)
 Frame = +1

Query: 24  KSNLLSRFTRNEFNLESKSTIGVEFATRSIQVDGKTIKAQIWDTAGQERYRAITSAYYRG 83
           K+ L+  F  ++FN   + T+GV++  +   V+G  ++  +WD +G   Y  + +  Y G
Sbjct: 1   KTCLIKHFCESKFNQGYQPTVGVDYGFKIQTVNGVDMRVHMWDLSGSNEYLDVRNELYTG 180

Query: 84  AVGALLVYDIAKHLTYENVERWLKELRDHADSNIVIMLVGNK 125
           +    +V+D++   ++E ++ WL+E+   A  + + ++VGN+
Sbjct: 181 SDAIFIVFDVSNTPSFEALDSWLREINRFATGSPLNVIVGNR 306
>14119
          Length = 602

 Score = 59.3 bits (142), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 33/78 (42%), Positives = 43/78 (55%), Gaps = 1/78 (1%)
 Frame = +1

Query: 98  TYENVERWLKELRDHADSNIVIMLVGNKSDL-RHLRAVPTDEARAFAEKNNLSFIETSAL 156
           T+     W+KELR     +++I+L GNK+DL    RAV  D+AR FAE N L F E SA 
Sbjct: 1   TFNRALAWVKELRQQNAGSVLIVLAGNKADLASEHRAVSADDARTFAEDNGLIFAEVSAK 180

Query: 157 DSTNVEEAFKNILTEIYR 174
               V E F  I  ++ R
Sbjct: 181 TGMAVSEVFMTIAHKLVR 234
>29380
          Length = 853

 Score = 58.9 bits (141), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 34/93 (36%), Positives = 53/93 (56%), Gaps = 2/93 (2%)
 Frame = -2

Query: 84  AVGALLVYDIAKHLTYENVERWLKELRDHADSNIVIMLVGNKSDL--RHLRAVPTDEARA 141
           A  A++VYD+    T+     W+KELR     +++I+L GNK DL  +H RAV  ++A++
Sbjct: 852 ASAAIIVYDVNIADTFSRALAWVKELRQQNTESVLIILAGNKVDLATQH-RAVSFEDAQS 676

Query: 142 FAEKNNLSFIETSALDSTNVEEAFKNILTEIYR 174
           FA +N L F E SA     V E F  +  ++ +
Sbjct: 675 FARENGLLFAEVSAKTGMAVNEIFMTLANQLIQ 577
>25618
          Length = 475

 Score = 54.7 bits (130), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 32/75 (42%), Positives = 41/75 (54%), Gaps = 1/75 (1%)
 Frame = +3

Query: 107 KELRDHADSNIVIMLVGNKSDL-RHLRAVPTDEARAFAEKNNLSFIETSALDSTNVEEAF 165
           KELR     +++I+L GNK+DL    RAV  D+AR FAE N L F E SA     V E F
Sbjct: 48  KELRQQNAGSVLIVLAGNKADLASEHRAVSADDARTFAEDNGLIFAEVSAKTGMAVSEVF 227

Query: 166 KNILTEIYRIVSQKQ 180
             I  ++ R   + Q
Sbjct: 228 MTIAHKLVRRAEEGQ 272
>10708
          Length = 2775

 Score = 43.5 bits (101), Expect(2) = 6e-08,   Method: Compositional matrix adjust.
 Identities = 29/78 (37%), Positives = 42/78 (53%), Gaps = 13/78 (16%)
 Frame = -3

Query: 101  NVERWLKELRDHADSNIVIMLVGNKSDLRH----------LRAVPT--DEARAFAEK-NN 147
            ++++W  E+R H   N+ I+LVGNK DLR+          ++  P   DE RA +EK N 
Sbjct: 2596 SLKKWTPEVR-HFCPNVPIILVGNKKDLRNDENTKRELMKMKQEPVRLDEGRAMSEKINA 2420

Query: 148  LSFIETSALDSTNVEEAF 165
             S++E SA     V E F
Sbjct: 2419 YSYLECSAKTKEGVREVF 2366

 Score = 29.6 bits (65), Expect(2) = 6e-08,   Method: Compositional matrix adjust.
 Identities = 13/45 (28%), Positives = 22/45 (48%)
 Frame = -2

Query: 58   KTIKAQIWDTAGQERYRAITSAYYRGAVGALLVYDIAKHLTYENV 102
            + ++  +WDTAGQE Y  +    Y      L+ + I    + EN+
Sbjct: 2729 QQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENI 2595
>24619
          Length = 509

 Score = 52.8 bits (125), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 34/105 (32%), Positives = 54/105 (51%), Gaps = 2/105 (1%)
 Frame = -2

Query: 70  QERYRAITSAYYRGAVGALLVYDIAKHLTYENVERWLKELRDHADSNIVIM-LVGNKSDL 128
           QE + A+   Y R   G LLV+ +  + ++EN+  +  ++    D +   M L  NK DL
Sbjct: 508 QEEFSAMREQYMRKGDGFLLVFSVIDYQSFENMVNFHTQILRVKDRDTYPMILCANKVDL 329

Query: 129 RHLRAVPTDEARAFAEKNNLSFIETSALDST-NVEEAFKNILTEI 172
            H R V  ++ R  A +  + +IETSA D   NV+ AF  ++  I
Sbjct: 328 VHQRKVSEEQVRDLATRLRIPYIETSAKDPPLNVDLAFHQVVRVI 194
>19046
          Length = 445

 Score = 52.8 bits (125), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 34/105 (32%), Positives = 54/105 (51%), Gaps = 2/105 (1%)
 Frame = -2

Query: 70  QERYRAITSAYYRGAVGALLVYDIAKHLTYENVERWLKE-LRDHADSNIVIMLVGNKSDL 128
           QE + A+   Y R   G LLV+ +    ++EN+  +  + LR     +  ++L  NK DL
Sbjct: 444 QEEFSAMREQYMRKGDGFLLVFSVTDFRSFENMANFHTQILRVKDRDSYPMILCANKVDL 265

Query: 129 RHLRAVPTDEARAFAEKNNLSFIETSALDST-NVEEAFKNILTEI 172
            H R V  ++ R  A +  + +IETSA D   NV+ AF  ++  I
Sbjct: 264 VHQRKVSEEQVRDLATRLRIPYIETSAKDPPLNVDLAFHQVVRVI 130
>14775
          Length = 380

 Score = 50.4 bits (119), Expect = 6e-07,   Method: Compositional matrix adjust.
 Identities = 47/175 (26%), Positives = 72/175 (41%), Gaps = 3/175 (1%)
 Frame = -2

Query: 24  KSNLLSRFTRNEFNLESKSTIGV---EFATRSIQVDGKTIKAQIWDTAGQERYRAITSAY 80
           K+ LL R+ +  F   +  TI V   EF     + D   ++  +WDT G E YR++  ++
Sbjct: 379 KTCLLRRYQKGFFMDRTMPTIAVLCSEF--NESRTDPLNVRYTLWDTGGAETYRSLWVSH 206

Query: 81  YRGAVGALLVYDIAKHLTYENVERWLKELRDHADSNIVIMLVGNKSDLRHLRAVPTDEAR 140
           +RGA  ALLVYD                                         V  +  +
Sbjct: 205 FRGAQVALLVYD-----------------------------------------VTCERGQ 149

Query: 141 AFAEKNNLSFIETSALDSTNVEEAFKNILTEIYRIVSQKQIADRAAHDESPGNNV 195
           AFA +   +F ETS++   NV+  F     EI  I+++ Q   R+AH E   + V
Sbjct: 148 AFATQCGYTFFETSSVTGKNVDAVFW----EIAFILARLQ---RSAHLELSMDTV 5
>31291
          Length = 446

 Score = 50.4 bits (119), Expect = 6e-07,   Method: Compositional matrix adjust.
 Identities = 26/69 (37%), Positives = 39/69 (56%), Gaps = 1/69 (1%)
 Frame = -1

Query: 63  QIWDTAGQERYRAITSAYYRGAVGALLVYDIAKHLTYENVE-RWLKELRDHADSNIVIML 121
           Q+WDTAGQE Y  +    Y      +L + +    + +NV+ +W  E+R H D ++ I+L
Sbjct: 443 QLWDTAGQEDYDRLRPLAYPNTDVFMLXFSLMSEASMKNVKVKWYPEIRHH-DPHVPIVL 267

Query: 122 VGNKSDLRH 130
           VG K DLR 
Sbjct: 266 VGTKLDLRQ 240
>09827
          Length = 1201

 Score = 46.2 bits (108), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 35/147 (23%), Positives = 66/147 (44%), Gaps = 3/147 (2%)
 Frame = -3

Query: 12   FKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIQVDGKTIKAQIWDTAGQE 71
             +++++G    GK+ +L +    E  + +  TIG    T    V+ K I   +WD  GQ+
Sbjct: 1112 MRILMVGLDAAGKTTILYKLKLGEI-VTTIPTIGFNVET----VEYKNISFTVWDVGGQD 948

Query: 72   RYRAITSAYYRGAVGALLVYDIA-KHLTYENVERWLKELRDHADSNIVIMLVGNKSDLRH 130
            + R +   Y++   G + V D   K    E  E   + L +    + V+++  NK DL H
Sbjct: 947  KIRPLWRHYFQNTQGLIFVVDSNDKERVQEAREELTRMLNEDELRDAVLLVFANKQDLPH 768

Query: 131  LRAVP--TDEARAFAEKNNLSFIETSA 155
              A    T++      +N   +I+++ 
Sbjct: 767  AMATAEITEKLGLHGLRNRTWYIQSTC 687
>12443
          Length = 837

 Score = 43.1 bits (100), Expect = 8e-05,   Method: Compositional matrix adjust.
 Identities = 33/128 (25%), Positives = 63/128 (49%), Gaps = 9/128 (7%)
 Frame = -3

Query: 12  FKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVE----FATRSIQVDGKTI--KAQIW 65
           +KV+L+G +GVGK++ +++ T N+  L    T G++    +    I+  GKT+  + Q++
Sbjct: 580 YKVMLVGKTGVGKTSTVAKLTGNDIPLTHNETPGLQTSHLYWPGKIKHLGKTVLFQIQLF 401

Query: 66  DTAGQ---ERYRAITSAYYRGAVGALLVYDIAKHLTYENVERWLKELRDHADSNIVIMLV 122
           D AG+   +RY  I  A   G  G + ++      +++ + + L       D  I  + +
Sbjct: 400 D-AGETALKRYDHILPACQDGVDGIMFLFSFVDKGSFDEIPQLLTRFTTLEDG-ICKIAL 227

Query: 123 GNKSDLRH 130
           G K    H
Sbjct: 226 GTKYPFPH 203
>08153
          Length = 1703

 Score = 41.2 bits (95), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 33/122 (27%), Positives = 56/122 (45%), Gaps = 6/122 (4%)
 Frame = +1

Query: 13  KVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIQVDGKTIKAQIWDTAGQER 72
           +++++G    GK+ +L +    E  + +  TIG    T    V+ K I   +WD  GQ++
Sbjct: 88  RILMVGLDAAGKTTILYKLKLGEI-VTTIPTIGFNVET----VEYKNISFTVWDVGGQDK 252

Query: 73  YRAITSAYYRGAVGALLVYDIAK----HLTYENVERWLKE--LRDHADSNIVIMLVGNKS 126
            R +   Y++   G + V D       +   E + R L E  LRD      +I++  NK 
Sbjct: 253 IRPLWRHYFQNTQGLIFVVDSNDRERINEAKEELARMLNEDDLRDA-----IILVFANKQ 417

Query: 127 DL 128
           DL
Sbjct: 418 DL 423
>25796
          Length = 422

 Score = 38.1 bits (87), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 15/27 (55%), Positives = 19/27 (70%)
 Frame = -1

Query: 5  DDEYDYLFKVVLIGDSGVGKSNLLSRF 31
           + YDYLFK ++IG +G GKS LL  F
Sbjct: 86 SETYDYLFKFLIIGSAGSGKSCLLHHF 6
>10862
          Length = 2896

 Score = 37.7 bits (86), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 19/66 (28%), Positives = 31/66 (46%), Gaps = 1/66 (1%)
 Frame = -3

Query: 64   IWDTAGQERYRAITSAYYRGAVGALLVYDIAKHLTYENVERWLKE-LRDHADSNIVIMLV 122
            +WD  GQ++ R +   YY G  G + V D A     +   + L   + D    + +I++ 
Sbjct: 2474 VWDVGGQDKIRPLWRHYYTGTQGLIFVVDCADRDRIDEARQELHRIINDREMRDAIILIF 2295

Query: 123  GNKSDL 128
             NK DL
Sbjct: 2294 ANKQDL 2277
>31932
          Length = 437

 Score = 37.4 bits (85), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 21/59 (35%), Positives = 35/59 (59%), Gaps = 1/59 (1%)
 Frame = -1

Query: 115 SNIVIMLVGNKSDLRHLRAVPTDEARAFAEKNN-LSFIETSALDSTNVEEAFKNILTEI 172
           S +  +L+GNKSDL H R V  DE     ++++ L + ETS  D T ++E+   ++ E+
Sbjct: 407 STVPCLLLGNKSDLGH-REVEQDEIEDLCKEHDFLGWSETSVKDGTMIDESMNYLIEEM 234
>33605
          Length = 888

 Score = 36.6 bits (83), Expect = 0.009,   Method: Compositional matrix adjust.
 Identities = 21/92 (22%), Positives = 43/92 (46%)
 Frame = +1

Query: 13  KVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIQVDGKTIKAQIWDTAGQER 72
           +++++G    GK+ +L +F   + +  S  T+G    T    ++ +  K  +WD  GQ+ 
Sbjct: 502 RLLMLGLDNAGKTTILKKFNGEDIDTIS-PTLGFNIKT----LEHRGFKLNVWDVGGQQS 666

Query: 73  YRAITSAYYRGAVGALLVYDIAKHLTYENVER 104
            R+    Y+    G + V D A  +   + +R
Sbjct: 667 LRSYWRNYFESTDGLVWVVDSADRMRIADCKR 762
>22318
          Length = 808

 Score = 27.3 bits (59), Expect = 4.8,   Method: Compositional matrix adjust.
 Identities = 13/23 (56%), Positives = 15/23 (65%)
 Frame = +3

Query: 13  KVVLIGDSGVGKSNLLSRFTRNE 35
           +V LIG   VGKS LLS  T+ E
Sbjct: 243 RVALIGFPSVGKSTLLSTLTKTE 311
>11062
          Length = 1716

 Score = 26.6 bits (57), Expect = 7.5,   Method: Compositional matrix adjust.
 Identities = 11/29 (37%), Positives = 19/29 (65%)
 Frame = +2

Query: 74  RAITSAYYRGAVGALLVYDIAKHLTYENV 102
           + +T   +RG++G+ L+Y+  K L  ENV
Sbjct: 74  KIVTLRQFRGSLGSFLLYNETKSLFSENV 160
>06883
          Length = 1257

 Score = 26.6 bits (57), Expect = 8.9,   Method: Compositional matrix adjust.
 Identities = 11/29 (37%), Positives = 19/29 (65%)
 Frame = +3

Query: 74  RAITSAYYRGAVGALLVYDIAKHLTYENV 102
           + +T   +RG++G+ L+Y+  K L  ENV
Sbjct: 72  KIVTLRQFRGSLGSFLLYNETKSLFSENV 158
>31928
          Length = 429

 Score = 26.2 bits (56), Expect = 9.8,   Method: Compositional matrix adjust.
 Identities = 29/94 (30%), Positives = 44/94 (46%), Gaps = 6/94 (6%)
 Frame = +2

Query: 38  LESKSTIGVE-FATRSIQVD-GKTIKAQIWDT---AGQERYRAITSAYYRGAVGALLVYD 92
           LES S   +E   T  I+ D G   K +I+DT   A +     +   Y     G +LVYD
Sbjct: 32  LESPSHSTIEDIYTAVIETDRGVKEKVRIFDTGAAALETTEGDLPKHYLNFPDGFVLVYD 211

Query: 93  IAKHLTYENVERWLKELRDHADSNIVIMLV-GNK 125
                ++  +++  K++  H D   V M+V GNK
Sbjct: 212 TTSWESFRRLDKLKKDIDKHRDKREVHMIVIGNK 313
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|78191789|ref|NP_080358.3| dedicator of cytokinesis 7
[Mus musculus]
         (2098 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

25905                                                                 157   3e-38
17591                                                                  35   0.47 
06850                                                                  33   1.8  
>25905
          Length = 482

 Score =  157 bits (398), Expect = 3e-38,   Method: Compositional matrix adjust.
 Identities = 76/165 (46%), Positives = 106/165 (64%)
 Frame = +3

Query: 666 PVGYTWIPMLQNGRLKTGQFCLPVSLEKPPQAYSVLSPEVPLPGMKWVDNHKGVFNVEVV 725
           PVGYTW+P+   GRL TG+  LPVS+E+ P  YS+  P+  L  MKWVDNHKGVF V + 
Sbjct: 3   PVGYTWVPLFHEGRLVTGEMSLPVSVERLPPHYSMYHPDAQLQHMKWVDNHKGVFTVNIK 182

Query: 726 AVSSIHTQDPYLDKFFALVNALDEHMFPVRIGDMRIMENNLESELKSSISALNSSQLEPV 785
           A+SS+H QD ++D+F  L N + +   P R+      EN  E+ELK SI  + +++ E +
Sbjct: 183 AISSVHAQDEHIDRFMHLWNFVQDQKLPPRMS-----ENGFENELKRSIMDIVNARGESL 347

Query: 786 VRFXXXXXXXXXXXVVRPPVIAGQIVNLGQASFEAMASIINRLHK 830
           V F           +VRPP+I G IVN+GQA+FEA+A I+ R+H+
Sbjct: 348 VHFLYLILDKLICLMVRPPLIGGNIVNVGQATFEALAQIVRRVHE 482
>17591
          Length = 474

 Score = 34.7 bits (78), Expect = 0.47,   Method: Composition-based stats.
 Identities = 20/46 (43%), Positives = 27/46 (58%), Gaps = 2/46 (4%)
 Frame = -2

Query: 1449 IIVQTVSVTESKESILGGVLKVLL--QSMACNQSAVYLQHCFATQR 1492
            ++VQ + V   KES L  +LKV L  QS+  + S+  LQ CF  QR
Sbjct: 239  LVVQVIPVDVGKESFLLDLLKVSLGPQSLLLSPSSAALQGCFCRQR 102
>06850
          Length = 1039

 Score = 32.7 bits (73), Expect = 1.8,   Method: Composition-based stats.
 Identities = 16/45 (35%), Positives = 23/45 (51%)
 Frame = +2

Query: 1052 SVMDRGFVFSLIKSCYKQVSAKLYSLPNPSVLVSLRLDFLRIICS 1096
            S+MD GF+ S+I  C      K Y   +   LVS +L + R  C+
Sbjct: 287  SLMDHGFIHSMINQCLHHGEVK*YQC*DNVFLVSYKLIYYRYNCT 421
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|86991442|ref|NP_001034443.1| lin 7 homolog a isoform
1 [Mus musculus]
         (233 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

20073                                                                 154   3e-38
08480                                                                  59   1e-09
03831                                                                  45   2e-05
38751                                                                  39   0.002
26154                                                                  34   0.053
39267                                                                  31   0.39 
37239                                                                  28   2.2  
>20073
          Length = 582

 Score =  154 bits (389), Expect = 3e-38,   Method: Compositional matrix adjust.
 Identities = 74/93 (79%), Positives = 86/93 (92%)
 Frame = +3

Query: 117 GLGFNVMGGKEQNSPIYISRIIPGGVAERHGGLKRGDQLLSVNGVSVEGEHHEKAVELLK 176
           GLGFNVMGGKEQ+SPIYISRIIPGGVA+R   LKRGDQLLSVNGVSVEGE+HEKAVELLK
Sbjct: 3   GLGFNVMGGKEQSSPIYISRIIPGGVADRLNCLKRGDQLLSVNGVSVEGEYHEKAVELLK 182

Query: 177 AAKDSVKLVVRYTPKVLEEMEARFEKLRTARRR 209
            A+ SV+LVVRYTP++LEEMEARFE+ + +R++
Sbjct: 183 LAQGSVRLVVRYTPQILEEMEARFERQKNSRKQ 281
>08480
          Length = 698

 Score = 59.3 bits (142), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 28/64 (43%), Positives = 42/64 (65%)
 Frame = -1

Query: 141 GVAERHGGLKRGDQLLSVNGVSVEGEHHEKAVELLKAAKDSVKLVVRYTPKVLEEMEARF 200
           G A+  G L+RGD++LSVN V VE   HE+A + LK A D+V+++ +Y P+     EA+ 
Sbjct: 698 GPADLSGDLRRGDKILSVNDVDVERATHEQAAQALKRAGDTVEIIAQYKPEDYNRFEAKI 519

Query: 201 EKLR 204
           + LR
Sbjct: 518 QDLR 507
>03831
          Length = 1143

 Score = 45.4 bits (106), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 28/83 (33%), Positives = 46/83 (55%), Gaps = 2/83 (2%)
 Frame = +3

Query: 106 PRVVELPKTDE--GLGFNVMGGKEQNSPIYISRIIPGGVAERHGGLKRGDQLLSVNGVSV 163
           PR+  L K  +  G GFN+   K++    YI  + P   AE  GGLK GD+++ VNG ++
Sbjct: 576 PRLCHLCKWADFDGYGFNLHAEKDKPGQ-YIGSVDPNSPAET-GGLKEGDRIIEVNGENI 749

Query: 164 EGEHHEKAVELLKAAKDSVKLVV 186
           E  +H   ++ +K+  D   ++V
Sbjct: 750 ETTNHTAVIQNIKSRGDKTSMLV 818

 Score = 44.3 bits (103), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 27/83 (32%), Positives = 48/83 (57%), Gaps = 2/83 (2%)
 Frame = +3

Query: 106 PRVVELPKTDE--GLGFNVMGGKEQNSPIYISRIIPGGVAERHGGLKRGDQLLSVNGVSV 163
           PR+  + +  +  G GFN+   K + +  +I ++  G  AE   GLK GD+++ VNG ++
Sbjct: 129 PRLCHIVRWSDFNGYGFNLHAEKGK-AGQFIGKVDEGSPAEA-AGLKAGDRIVEVNGTNI 302

Query: 164 EGEHHEKAVELLKAAKDSVKLVV 186
             E+H++ V  +KA  D  +L+V
Sbjct: 303 GNENHQQVVGRIKAGGDETRLLV 371
>38751
          Length = 329

 Score = 39.3 bits (90), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 23/64 (35%), Positives = 35/64 (54%)
 Frame = +3

Query: 122 VMGGKEQNSPIYISRIIPGGVAERHGGLKRGDQLLSVNGVSVEGEHHEKAVELLKAAKDS 181
           + GGKE  +PI +  I  G  AE+ G L  GD++L VNG       H +AV +++ A + 
Sbjct: 9   IKGGKEYGTPIVVYVIEEGCQAEQQG-LNIGDRILDVNGTDFTHLTHAEAVTIMRNAWNV 185

Query: 182 VKLV 185
           +  V
Sbjct: 186 IMTV 197
>26154
          Length = 446

 Score = 33.9 bits (76), Expect = 0.053,   Method: Compositional matrix adjust.
 Identities = 15/42 (35%), Positives = 25/42 (59%)
 Frame = -3

Query: 118 LGFNVMGGKEQNSPIYISRIIPGGVAERHGGLKRGDQLLSVN 159
           LG  + G ++    I IS +  GG+A++ G +  GD+LL +N
Sbjct: 195 LGITISGTEDPLDNIVISELTAGGLAQKTGAMHVGDRLLGIN 70

 Score = 29.3 bits (64), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 16/47 (34%), Positives = 28/47 (59%)
 Frame = -3

Query: 141 GVAERHGGLKRGDQLLSVNGVSVEGEHHEKAVELLKAAKDSVKLVVR 187
           G A R G ++ GD+L+++N V ++    + A  LL+   + VKL V+
Sbjct: 408 GSAHRCGSIQAGDKLMAINDVRLDTCTVDDATHLLELPDELVKLKVQ 268
>39267
          Length = 456

 Score = 31.2 bits (69), Expect = 0.39,   Method: Compositional matrix adjust.
 Identities = 20/62 (32%), Positives = 33/62 (53%)
 Frame = +1

Query: 117 GLGFNVMGGKEQNSPIYISRIIPGGVAERHGGLKRGDQLLSVNGVSVEGEHHEKAVELLK 176
           GLGFN+ G       IY+S++   G A   G +  GD++ SV  ++ +   +E A+ +L 
Sbjct: 115 GLGFNISGNMRDG--IYVSQLHNRGPASESGKIHVGDRIQSVT-IAYDNIVYEDALTILS 285

Query: 177 AA 178
            A
Sbjct: 286 YA 291
>37239
          Length = 453

 Score = 28.5 bits (62), Expect = 2.2,   Method: Compositional matrix adjust.
 Identities = 21/60 (35%), Positives = 30/60 (50%), Gaps = 2/60 (3%)
 Frame = -2

Query: 139 PGGVAERHGGLKRGDQLLSVNGVSVEGEHHEKAVELLKA--AKDSVKLVVRYTPKVLEEM 196
           P   A R   +  GD+LL +NG  + G  H  A  ++K+  A D VKLVV      L+ +
Sbjct: 449 PDSPAARDARIHVGDELLEINGNLLHGRCHLNASAIVKSVTAPD-VKLVVNRRADSLDRI 273
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|94721328|ref|NP_038961.2| vesicle-associated membrane
protein, associated protein A [Mus musculus]
         (249 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

34509                                                                 154   3e-38
11078                                                                  35   0.022
>34509
          Length = 408

 Score =  154 bits (389), Expect = 3e-38,   Method: Compositional matrix adjust.
 Identities = 68/101 (67%), Positives = 85/101 (84%)
 Frame = +2

Query: 1   MASASGAMAKHEQILVLDPPSDLKFKGPFTDVVTTNLKLQNPSDRKVCFKVKTTAPRRYC 60
           + S++  M+K EQ LVLDP ++L FKGPFTD VT  LKLQNP+++K+CFKVKTTAP+RYC
Sbjct: 59  IISSTNKMSKTEQALVLDPATELVFKGPFTDTVTAVLKLQNPTEKKICFKVKTTAPKRYC 238

Query: 61  VRPNSGIIDPGSIVTVSVMLQPFDYDPNEKSKHKFMVQTIF 101
           VRPNSGI+DP    +V VMLQPF+YDP+EKSKHKFMVQ++ 
Sbjct: 239 VRPNSGILDPNGTASVQVMLQPFEYDPSEKSKHKFMVQSML 361
>11078
          Length = 469

 Score = 35.4 bits (80), Expect = 0.022,   Method: Compositional matrix adjust.
 Identities = 15/24 (62%), Positives = 19/24 (79%)
 Frame = +1

Query: 7   AMAKHEQILVLDPPSDLKFKGPFT 30
            M+K EQ LVLDPP++L+FKG  T
Sbjct: 316 TMSKTEQALVLDPPTELQFKGKMT 387
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|21704242|ref|NP_663596.1| CaM kinase-like
vesicle-associated [Mus musculus]
         (512 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

15910                                                                 155   4e-38
01392                                                                 117   8e-27
21079                                                                  90   3e-21
30755                                                                  96   3e-20
12721                                                                  93   3e-19
01707                                                                  88   7e-18
14420                                                                  87   2e-17
13592                                                                  83   3e-16
01060                                                                  82   4e-16
00300                                                                  80   2e-15
17975                                                                  77   2e-14
18484                                                                  75   5e-14
14126                                                                  71   1e-12
13066                                                                  69   5e-12
03240                                                                  67   1e-11
09606                                                                  67   1e-11
00392                                                                  67   2e-11
26711                                                                  66   4e-11
31885                                                                  65   7e-11
00486                                                                  64   2e-10
18921                                                                  63   3e-10
29581                                                                  62   7e-10
27546                                                                  62   7e-10
01756                                                                  61   9e-10
06405                                                                  59   7e-09
18663                                                                  57   1e-08
02638                                                                  56   3e-08
27274                                                                  56   4e-08
38560                                                                  55   5e-08
04591                                                                  55   6e-08
01718                                                                  55   7e-08
21433                                                                  55   1e-07
25019                                                                  41   4e-07
19301                                                                  52   5e-07
21808                                                                  50   3e-06
19094                                                                  50   3e-06
21418                                                                  49   5e-06
04138                                                                  48   9e-06
13212                                                                  48   9e-06
07291                                                                  48   9e-06
09007                                                                  48   1e-05
04852                                                                  47   2e-05
32957                                                                  47   2e-05
20152                                                                  46   3e-05
20655                                                                  45   6e-05
19761                                                                  45   7e-05
31489                                                                  45   1e-04
36002                                                                  44   1e-04
12786                                                                  44   1e-04
32000                                                                  44   1e-04
29590                                                                  44   1e-04
36481                                                                  44   2e-04
28638                                                                  42   5e-04
31120                                                                  41   0.001
17722                                                                  40   0.002
01966                                                                  40   0.002
14116                                                                  38   0.010
11185                                                                  37   0.019
07940                                                                  37   0.023
01106                                                                  37   0.026
17300                                                                  37   0.027
26009                                                                  35   0.052
03508                                                                  35   0.082
18401                                                                  34   0.11 
03294                                                                  34   0.13 
37063                                                                  33   0.22 
00715                                                                  33   0.40 
22644                                                                  32   0.53 
06358                                                                  32   0.65 
03106                                                                  31   0.93 
37602                                                                  31   0.98 
21800                                                                  30   1.7  
18996                                                                  30   2.2  
32473                                                                  30   3.4  
17516                                                                  29   4.2  
17253                                                                  28   7.6  
>15910
          Length = 1361

 Score =  155 bits (392), Expect = 4e-38,   Method: Compositional matrix adjust.
 Identities = 83/213 (38%), Positives = 132/213 (61%), Gaps = 2/213 (0%)
 Frame = +2

Query: 106 EVFDWILDQGYYSERDTSNVVRQVLEAVAYLHSLKIVHRNLKLENLVYYNRLKNSKIVIS 165
           E+FD I+ +G Y+E+D +  +  +L  V Y+H+  +VHR+LK ENL+Y     +SK+ ++
Sbjct: 422 ELFDRIVTRGQYTEKDAARAISDILHGVQYIHANGVVHRDLKPENLLYECMTDDSKLKLA 601

Query: 166 DFHLAKLENGLIKEP--CGTPEYLAPEVVGRQRYGRPVDCWAIGVIMYILLSGNPPFYEE 223
           DF L+++    ++    CGTP Y APEV+   +Y   VD W++GVI YILL G  PF+ E
Sbjct: 602 DFGLSRIIEPEVQMSTVCGTPGYCAPEVLKGDKYTPSVDMWSVGVIAYILLCGYEPFFAE 781

Query: 224 VEEDDYENHDKNLFRKILAGDYEFDSPYWDDISQAAKDLVTRLMEVEQDQRITAEEAISH 283
              +++E     ++RKI+ G+Y+FD  YW +IS+ AKD+V +L+ ++  +R+TA EA+  
Sbjct: 782 ---NEFE-----MYRKIIKGEYKFDEEYWSEISENAKDVVRKLLVIDPKKRLTATEALRL 937

Query: 284 EWISGNAASDKNIKDGVCAQIEKNFARAKWKKA 316
            W+ G A    N++  +    E N AR K K A
Sbjct: 938 PWVKGVATKTTNMEITMNKLKEFN-ARRKLKCA 1033
>01392
          Length = 1806

 Score =  117 bits (294), Expect = 8e-27,   Method: Compositional matrix adjust.
 Identities = 71/192 (36%), Positives = 100/192 (52%), Gaps = 20/192 (10%)
 Frame = -1

Query: 115  GYYSERDTSNVVRQVLEAVAYLHSLKIVHRNLKLENLVYYNRLKNSKIVISDFHLAK--- 171
            G+  ER+ S VVR +  A+ +LHS  I HR+LK EN++  +      + I DF LA    
Sbjct: 1806 GHLCEREASLVVRHIARALDFLHSKGIAHRDLKPENILCEHLDDVVPVKICDFDLASGIS 1627

Query: 172  -----LENGLIKEPCGTPEYLAPEVVGRQ-----RYGRPVDCWAIGVIMYILLSGNPPFY 221
                  +   +  P G+ EY+APEVV         Y +  D W++G+I+YI+L G PPFY
Sbjct: 1626 CDGDGTKTPELLTPVGSAEYMAPEVVDAWVGDSFSYDKRCDLWSLGIILYIMLCGYPPFY 1447

Query: 222  EEVEEDDYEN-----HDKN--LFRKILAGDYEFDSPYWDDISQAAKDLVTRLMEVEQDQR 274
             +  ED   N     HD    LF  I  G Y+F S  W  IS +AKDL+  L+  E  +R
Sbjct: 1446 GQCGEDCGWNRGEACHDCQDMLFNSIQDGHYKFPSQEWTSISSSAKDLIRHLLVREPRKR 1267

Query: 275  ITAEEAISHEWI 286
             +A + + H WI
Sbjct: 1266 YSAADVLKHPWI 1231
>21079
          Length = 878

 Score = 90.1 bits (222), Expect(2) = 3e-21,   Method: Compositional matrix adjust.
 Identities = 54/144 (37%), Positives = 79/144 (54%), Gaps = 3/144 (2%)
 Frame = +1

Query: 79  HPNILQLVDVFVTRKEYFIFLELATGREVFDWIL-DQGYYSERDTSNVVRQVLEAVAYLH 137
           HP +L L D F   +   + +E     E+F+ ++ D    +ERD  + VRQ+   V Y+H
Sbjct: 1   HPKLLMLWDAFEAPRTMVLVMEFVGAGELFERVIRDDFVLTERDCVHFVRQICSGVGYMH 180

Query: 138 SLKIVHRNLKLENLVYYNRLKNSKIVISDFHLAKL--ENGLIKEPCGTPEYLAPEVVGRQ 195
           +  I+H +LK EN++  +   N +I I DF LA+       ++   GTPE++APEVV   
Sbjct: 181 TQSILHLDLKPENVLCVSDNSN-QIKIIDFGLARFYKPGDSLQVLFGTPEFIAPEVVNYD 357

Query: 196 RYGRPVDCWAIGVIMYILLSGNPP 219
                 D W+IGVI YILLSG  P
Sbjct: 358 EINFTTDMWSIGVICYILLSGLSP 429

 Score = 30.0 bits (66), Expect(2) = 3e-21,   Method: Compositional matrix adjust.
 Identities = 23/79 (29%), Positives = 37/79 (46%), Gaps = 8/79 (10%)
 Frame = +2

Query: 256 SQAAKDLVTRLMEVEQDQRITAEEAISHEWISGNAASDKNIKDGVCAQIEKN-----FAR 310
           S  AKD +      E+++R+T E+   H W+   A  D+ I+   C ++  +      AR
Sbjct: 512 SDNAKDFIGNC*SREKEKRMTIEQCDKHSWL---AEQDQRIR---CKRLNTDRLRCFMAR 673

Query: 311 AKWKK---AVRVTTLMKRL 326
            KW+K   A+R    M  L
Sbjct: 674 RKWQKTGNAIRALGRMASL 730
>30755
          Length = 1137

 Score = 95.9 bits (237), Expect = 3e-20,   Method: Compositional matrix adjust.
 Identities = 61/162 (37%), Positives = 88/162 (54%), Gaps = 3/162 (1%)
 Frame = +2

Query: 117 YSERDTSNVVRQVLEAVAYLHSLKIVHRNLKLENLVYYNRLKNSKIVISDFHLAKLE--- 173
           ++E  T     +++ A+ YLHS  I++R+LKLENL+     K+  I ++DF L K +   
Sbjct: 23  FTEERTRFYGAEIISALGYLHSQGIIYRDLKLENLLLD---KDGHIKVADFGLCKEDITY 193

Query: 174 NGLIKEPCGTPEYLAPEVVGRQRYGRPVDCWAIGVIMYILLSGNPPFYEEVEEDDYENHD 233
               K  CGTPEYLAPEV+    YGR VD W  GV+MY ++ G  PFY         +HD
Sbjct: 194 GRTTKTFCGTPEYLAPEVLDDNDYGRAVDWWGTGVVMYEMICGRLPFYN-------RDHD 352

Query: 234 KNLFRKILAGDYEFDSPYWDDISQAAKDLVTRLMEVEQDQRI 275
             LF  IL  D +F      +I+  AK L++ L+  +   R+
Sbjct: 353 V-LFTLILVEDVKFPR----NITDEAKSLLSGLLAKDPRNRL 463
>12721
          Length = 821

 Score = 92.8 bits (229), Expect = 3e-19,   Method: Compositional matrix adjust.
 Identities = 51/180 (28%), Positives = 100/180 (55%), Gaps = 3/180 (1%)
 Frame = +1

Query: 47  GKLHTCKKFQKRDGRKVRKAAKNEIGILKMVKHPNILQLVDVFVTRKEYFIFLELATGRE 106
           G+    KK   R  ++ R+   NE+ +++   HPNI+++ + ++   E ++ +E   G  
Sbjct: 160 GRQMAVKKMDLRKQQR-RELLFNEVVVMRDYHHPNIVEMYNSYLVNDELWVVMEFMEGGA 336

Query: 107 VFDWILDQGYYSERDTSNVVRQVLEAVAYLHSLKIVHRNLKLENLVYYNRLKNSKIVISD 166
           + D I+      E   + V R  L+A+A+LH+  ++HR++K ++++  +   + K+ + D
Sbjct: 337 LTD-IVTNNRMDEVQIATVCRACLKALAFLHANGVIHRDIKSDSILLSH---DGKVKLXD 504

Query: 167 FHL-AKLENGLIKEP--CGTPEYLAPEVVGRQRYGRPVDCWAIGVIMYILLSGNPPFYEE 223
           F   A++   L K     GTP ++APEV+ R  YG  VD W++G+++  ++   PPF+ E
Sbjct: 505 FGFCAQVTQDLQKRKSLVGTPYWMAPEVISRLPYGPEVDIWSLGIMVMEMIDAEPPFFNE 684
>01707
          Length = 757

 Score = 88.2 bits (217), Expect = 7e-18,   Method: Compositional matrix adjust.
 Identities = 62/195 (31%), Positives = 100/195 (51%), Gaps = 15/195 (7%)
 Frame = +1

Query: 38  IFRAKDKTTGKLHTCKKF-QKRDGRKVRKAAKNEIGILKMVKHPNILQLVDVFVTRKEYF 96
           +F+ ++K T +L   KKF +  D   ++K A  EI +LK +KHPN+++L++VF  +K   
Sbjct: 112 VFKCRNKETSQLVAIKKFVESEDDPLIKKIAMREIRMLKQLKHPNLVRLIEVFRRKKRLH 291

Query: 97  IFLELATGREVFDWILDQGYYSERD----------TSNVVRQVLEAVAYLHSLKIVHRNL 146
           +         VFD++ D    +E D             ++ Q L AV + H    +HR++
Sbjct: 292 L---------VFDYV-DHTLLNELDRYPRGLPEPMVKRIIYQTLLAVNFCHQYNTIHRDV 441

Query: 147 KLENLVYYNRLKNSKIVISDFHLAKLENGLIKE---PCGTPEYLAPE-VVGRQRYGRPVD 202
           K EN++     +  ++ + DF  A++  G   E      T  Y APE +VG  +YG PVD
Sbjct: 442 KPENILI---TRQGQVKLCDFGFARILTGPGDEYTDYVATRWYRAPELLVGDTQYGPPVD 612

Query: 203 CWAIGVIMYILLSGN 217
            WAIG +   LL+G 
Sbjct: 613 VWAIGCVFAELLTGQ 657
>14420
          Length = 528

 Score = 86.7 bits (213), Expect = 2e-17,   Method: Compositional matrix adjust.
 Identities = 47/158 (29%), Positives = 92/158 (58%), Gaps = 3/158 (1%)
 Frame = +2

Query: 69  NEIGILKMVKHPNILQLVDVFVTRKEYFIFLELATGREVFDWILDQGYYSERDTSNVVRQ 128
           NEI +++  ++PNI+  +D ++  +E ++ +E   G  + D ++ +    E   + V R+
Sbjct: 47  NEILVMRENQNPNIVNYLDSYLVGEELWVVMEFLAGGSLTD-VVTETCMDEGQIAAVCRE 223

Query: 129 VLEAVAYLHSLKIVHRNLKLENLVYYNRLKNSKIVISDFHL-AKL--ENGLIKEPCGTPE 185
            L+A+ +LH  +++HR++K +N++      +  + ++DF   A+L  E        GTP 
Sbjct: 224 CLQALEFLHENQVIHRDIKSDNILLG---MDGSVKLTDFGFCAQLSPEQSKRSTMVGTPY 394

Query: 186 YLAPEVVGRQRYGRPVDCWAIGVIMYILLSGNPPFYEE 223
           ++APEVV R++YG  VD W++GV+   ++ G PP+  E
Sbjct: 395 WMAPEVVTRKQYGPTVDIWSLGVMCIEMIEGEPPYLNE 508
>13592
          Length = 980

 Score = 82.8 bits (203), Expect = 3e-16,   Method: Compositional matrix adjust.
 Identities = 71/286 (24%), Positives = 139/286 (48%), Gaps = 10/286 (3%)
 Frame = +2

Query: 35  FCEIFRAKDKTTGKLHTCKKFQKRDGR-KVRKAAKNEIGILKMVKHPNILQLVDVFVTRK 93
           F +++ A +  TG+L   K+   + G  +  K    E+ IL+ +KH N+++   + V R+
Sbjct: 23  FGKVYTAVNNNTGELMAMKEIAIQPGETRALKNVAEELKILEGIKHKNLVRYYGIEVHRE 202

Query: 94  EYFIFLELATGREVFDWILDQGYYSERDTSNVVRQVLEAVAYLHSLKIVHRNLKLENLVY 153
           E  IF+EL +   +   +   G   E  +     Q+L  VA LH   IVHR++K  N+  
Sbjct: 203 ELLIFMELCSEGTLESLVELTGGLPEALSRRFTAQLLSGVAELHKHGIVHRDIKTANIFL 382

Query: 154 YNRLKNSKIVISDFHLA-KLEN-----GLIKEPCGTPEYLAPEVVGRQR---YGRPVDCW 204
            +   ++ + + DF  A K++      G ++   GT  Y+APEV  +     +GR  D W
Sbjct: 383 VD--GSNSLKLGDFGSAVKIQAHTTVPGELQGYVGTQAYMAPEVFTKTNSDGHGRLADIW 556

Query: 205 AIGVIMYILLSGNPPFYEEVEEDDYENHDKNLFRKILAGDYEFDSPYWDDISQAAKDLVT 264
           ++G ++  + SG  P+ +      ++++ + +F K+  G+    +P  + +SQ   D + 
Sbjct: 557 SVGCVVVEMASGKRPWAQ------FDSNFQIMF-KVGMGEKP-QAP--ESLSQEGHDFID 706

Query: 265 RLMEVEQDQRITAEEAISHEWISGNAASDKNIKDGVCAQIEKNFAR 310
             ++ +  QR++A E +   +       + N  + + AQ+  +F R
Sbjct: 707 HCLQHDPKQRLSAIELLEQNFCKSGRDEECN-SEQLHAQMRGSFRR 841
>01060
          Length = 1800

 Score = 82.4 bits (202), Expect = 4e-16,   Method: Compositional matrix adjust.
 Identities = 84/333 (25%), Positives = 147/333 (44%), Gaps = 28/333 (8%)
 Frame = +1

Query: 18  SEVTDRYDLGQVIKTEEFCEIFRAKDKTTGKLHTCKKFQKR---DGRKVRKAAKNEIGIL 74
           S++TD   +G+      +  +++ + + TG+    KK + R   DG  V  +A  EI +L
Sbjct: 73  SDLTDFQKIGE----GTYGVVYKCRHRATGRKLAMKKIRLRGSEDG--VPSSAIREIAML 234

Query: 75  KMVKHPNILQLVDVFVTRKEYFIFLELATG--REVFDWILDQGYYSERDTSNVVRQVLEA 132
           + ++H NI+ L DV +  +  F+  E  +   +   D   +      R   + V Q++  
Sbjct: 235 RELRHTNIVCLEDVIMEDERLFLVFEFLSMDLKMYIDKFPEGVVLDRRLVKSYVFQIVTG 414

Query: 133 VAYLHSLKIVHRNLKLENLVYYNRLKNSKIVISDFHLAK---LENGLIKEPCGTPEYLAP 189
           + + H  +IVHR+LK +NL+  +      I I+DF +A+   L          T  Y AP
Sbjct: 415 IXFCHQRRIVHRDLKPQNLLINH---TGAIKIADFGMARTFALPVRAYTHEVVTLWYRAP 585

Query: 190 EVV-GRQRYGRPVDCWAIGVIMYILLSGNPPFYEEVEEDDYENHDKNL----------FR 238
           E++ G  +Y  PVD W+IG I   +L   P F  + E D      + +          F 
Sbjct: 586 EILMGASKYSTPVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIFRIIGTPTEQTWPEFH 765

Query: 239 KILAGDYEFDSPYWD---------DISQAAKDLVTRLMEVEQDQRITAEEAISHEWISGN 289
           K+ A +  F  P W          D+     DL+ R ++ +  QRI+ ++ + H +    
Sbjct: 766 KLPAFNGMF--PLWKEGKLSETLTDLDSLGLDLIERTLKCDPAQRISCKKMLQHAYFLNV 939

Query: 290 AASDKNIKDGVCAQIEKNFARAKWKKAVRVTTL 322
             S K +   V +       R K+K+ +R  T+
Sbjct: 940 DTSVKPV--DVPSPEHS*STRLKYKETLRTKTI 1032
>00300
          Length = 2318

 Score = 79.7 bits (195), Expect = 2e-15,   Method: Compositional matrix adjust.
 Identities = 74/280 (26%), Positives = 136/280 (48%), Gaps = 14/280 (5%)
 Frame = -1

Query: 20   VTDRYDLGQVIKTEEFCEIFRAKDKTTGKLHTCK--KFQKRDGRKVRKAAKNEIGILKMV 77
            V  R+  G  I   +F +++ A + +TG+L   K  KFQ  D +++R+   +EI I + +
Sbjct: 1664 VNFRWQRGNKIGEGQFGKVYTAVNMSTGELMALKEMKFQPNDLQQLREMC-DEIKIFEGI 1488

Query: 78   KHPNILQLVDVFVTRKEYFIFLEL---ATGREVFDWILDQGYYSERDTSNVVRQVLEAVA 134
            +H N+++   V V + E  +F+E     T  E     L + Y   R T    R+++ AV 
Sbjct: 1487 QHENLVKYYGVEVHKDEMLMFMEYCDTGTIEEAAKMGLPE-YLIRRYT----REIVLAVN 1323

Query: 135  YLHSLKIVHRNLKLENLVYYNRLKNSKIVISDFHLA-KLEN-----GLIKEPCGTPEYLA 188
            +LH   IVHR++K  N+   +   N  + + DF  + KL++     G      GT  Y+A
Sbjct: 1322 HLHENSIVHRDIKGANIFLTS---NGHVKLGDFGCSVKLKSHTTMPGEFHNLVGTTAYMA 1152

Query: 189  PEVVGRQR---YGRPVDCWAIGVIMYILLSGNPPFYEEVEEDDYENHDKNLFRKILAGDY 245
            PEV  +     YGR  D W++G ++  + +G  P++      D +N+ + +++  +   +
Sbjct: 1151 PEVFTQNDQGGYGRAADIWSLGCVVIEMATGKRPWH------DLDNNYQIMYK--VGIGH 996

Query: 246  EFDSPYWDDISQAAKDLVTRLMEVEQDQRITAEEAISHEW 285
            +   P  D +S   K  +  +M  +  QR  A + + H +
Sbjct: 995  KPAVP--DSLSVEGKHFLDLIMCHDPAQRALASQLLDHTF 882
>17975
          Length = 449

 Score = 76.6 bits (187), Expect = 2e-14,   Method: Composition-based stats.
 Identities = 35/99 (35%), Positives = 65/99 (65%), Gaps = 1/99 (1%)
 Frame = +3

Query: 70  EIGILKMVKHPNILQLVDVFVTRKEYFIFLELATGREVFDWILDQ-GYYSERDTSNVVRQ 128
           E+  +K+V+HPN+++L +V  T+ + ++ LEL  G +++D+I+   G   E+      RQ
Sbjct: 114 EVRCMKLVQHPNVVRLYEVIDTQTKLYLILELGDGGDMYDYIMRHSGGLEEKLAKRYFRQ 293

Query: 129 VLEAVAYLHSLKIVHRNLKLENLVYYNRLKNSKIVISDF 167
           ++EA++Y H L +VHR+LK EN+V++   K   + ++DF
Sbjct: 294 IVEAISYCHKLHVVHRDLKPENVVFFE--KPGLVKLTDF 404
>18484
          Length = 635

 Score = 75.5 bits (184), Expect = 5e-14,   Method: Compositional matrix adjust.
 Identities = 40/124 (32%), Positives = 71/124 (57%), Gaps = 3/124 (2%)
 Frame = +1

Query: 111 ILDQGYYSERDTSNVVRQVLEAVAYLHSLKIVHRNLKLENLVYYNRLKNSKIVISDFHLA 170
           I  +G + E   +    ++   + +LH   I++R+LKL+N++  +      I I+DF + 
Sbjct: 16  IQQEGKFKEPVAAFYAAEIAVGLFFLHDQGIIYRDLKLDNVMLDSE---GHIKIADFGMC 186

Query: 171 K---LENGLIKEPCGTPEYLAPEVVGRQRYGRPVDCWAIGVIMYILLSGNPPFYEEVEED 227
           K     +   +  CGTP+Y+APE+V  Q Y + VD WA GV+++ +L+G PPF  E E++
Sbjct: 187 KEGMTGDATTRTFCGTPDYIAPEIVLYQPYSKSVDWWAYGVLLFEMLAGQPPFDGEDEDE 366

Query: 228 DYEN 231
            + +
Sbjct: 367 LFSS 378
>14126
          Length = 1265

 Score = 70.9 bits (172), Expect = 1e-12,   Method: Compositional matrix adjust.
 Identities = 78/303 (25%), Positives = 146/303 (48%), Gaps = 39/303 (12%)
 Frame = +3

Query: 23  RYDLGQVIKTEEFCEIFRAKD-KTTGKLHTCKKFQKRDGRK-VRKAAKNEIGILKMVK-- 78
           +Y+   VI    +  +++A+D +  G+    K+ +  +  + +   A  EI +LK ++  
Sbjct: 192 KYEEVAVIGNGAYGTVYKARDLRNQGEFVAMKRIRLNNTEEGMPMMAIREISMLKQLEQY 371

Query: 79  -HPNILQLVDV---FVTRKEYFIFLELATGREVFDWI-LDQGYYSERDTS---------N 124
            HPN+++L+DV    +T +E  + L       VF++I  D   Y  +  S         +
Sbjct: 372 EHPNVVRLLDVSHNTITDREIRLNL-------VFEYIEHDLATYLAKCPSPGLGPDRIKD 530

Query: 125 VVRQVLEAVAYLHSLKIVHRNLKLENLVYYNRLKNSKIVISDFHLAKLE--NGLIKEPCG 182
           ++ Q+L  V +LHS +IVHR+LK +NL+     K+ ++ ++DF LA++   +  +     
Sbjct: 531 LMLQLLNGVDFLHSNRIVHRDLKPQNLLIS---KDGRLKLADFGLARIYSFHMALTTVVV 701

Query: 183 TPEYLAPEVVGRQRYGRPVDCWAIGVIMYILLSGNPPFYEEVEEDDYENHDKNLFRKI-- 240
           T  Y +PEV+ +  YG  VD W+ G I   L +    F    E D      K +F  I  
Sbjct: 702 TLWYRSPEVLMQAEYGTSVDIWSCGCIFAELFTRRALFKGSSEFDQL----KKIFEVIGL 869

Query: 241 -LAGDY-EFDSPYWD---------------DISQAAKDLVTRLMEVEQDQRITAEEAISH 283
             AGD+ E  S + +               ++   AKDL+ +++  +  +RI++ E++ H
Sbjct: 870 PPAGDWPEGVSVHRNSFRPTPPVPLQTLVPEMDPQAKDLMEKMLVFKSGRRISSRESLLH 1049

Query: 284 EWI 286
            ++
Sbjct: 1050PYL 1058
>13066
          Length = 551

 Score = 68.9 bits (167), Expect = 5e-12,   Method: Compositional matrix adjust.
 Identities = 45/154 (29%), Positives = 74/154 (48%), Gaps = 9/154 (5%)
 Frame = +3

Query: 63  VRKAAKNEIGILKMVKHPNILQLVDVFVTRKEYFIFLELATGREVFDWILDQGYYSERDT 122
           V K    E+ +L  + HP I+Q+  +     + FIF+  A   ++  +I + G+  E+  
Sbjct: 105 VEKFFPRELDLLTKLDHPYIIQIHSILQRXPKNFIFMRFAERGDLLTYIQEVGFVKEKQA 284

Query: 123 SNVVRQVLEAVAYLHSLKIVHRNLKLENLVYYNRLKNSKIVISDFHLAKL----ENGLIK 178
                Q+  A+ YLHS  + HR+LK EN++  +   N K+    F  A +    E  + +
Sbjct: 285 KIWFYQMTTALNYLHSYDVAHRDLKCENILLSSHF-NVKLADFGFACACITESGEKYMSR 461

Query: 179 EPCGTPEYLAPEVVGRQRYGRP-----VDCWAIG 207
             CG+  Y APE+V    YG P      D W++G
Sbjct: 462 TYCGSAAYAAPEIV----YGAPYAPKVADAWSLG 551
>03240
          Length = 1683

 Score = 67.4 bits (163), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 73/308 (23%), Positives = 126/308 (40%), Gaps = 54/308 (17%)
 Frame = -3

Query: 35   FCEIFRAKDKTTGKLHTCKKFQKRDGRKVRKAA--KNEIGILKMVKHPNILQLVDVFVTR 92
            F E+   +   TG L+  K  +K D  K  + A  K E  IL    +  +++L   F   
Sbjct: 1252 FGEVSLCRKNDTGMLYAMKTLRKSDVLKRNQVAHVKAERDILAEADNEWVVKLYYSFQDH 1073

Query: 93   KEYFIFLELATGREVFDWILDQGYYSERDTSNVVRQVLEAVAYLHSLKIVHRNLKLENLV 152
               +  ++   G ++   ++      E      V ++++A+  +H +  +HR++K +N++
Sbjct: 1072 NYLYFVMDYVPGGDLMGLLIRMEILDEPLARFYVAELVQAIESVHRMGFIHRDIKPDNIL 893

Query: 153  YYNRLKNSKIVISDFHL-------------------AKLENGLIK----EPC-------- 181
                 +N  I ++DF L                   A+ ++  +K    E C        
Sbjct: 892  ID---RNGHIKLTDFGLCTGFRWTHNSKYYQRDGTHARQDSMEVKCQLDEQCQCEILKPL 722

Query: 182  ----------------GTPEYLAPEVVGRQR-YGRPVDCWAIGVIMYILLSGNPPFYEEV 224
                            GTP Y+APEV+ R   Y    D W++GVI++ +L G+PPFY   
Sbjct: 721  ERRRKREQRCLAHSLVGTPNYIAPEVLSRLGGYTSVCDWWSVGVILFEMLVGHPPFYANT 542

Query: 225  -EEDDYENHDKNLFRKILAGDYEFDSPYWDDISQAAKDLVTRLMEVEQDQRI---TAEEA 280
              E  Y         K++        P   ++SQ AKDL+ RL     D R+    A E 
Sbjct: 541  PAETQY---------KVINWKDMLKIPRESNLSQPAKDLILRLC-CGSDDRLGLNGAGEI 392

Query: 281  ISHEWISG 288
             +H + +G
Sbjct: 391  KTHMFFAG 368
>09606
          Length = 1300

 Score = 67.4 bits (163), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 59/261 (22%), Positives = 109/261 (41%), Gaps = 32/261 (12%)
 Frame = -3

Query: 64   RKAAKNEIGILKMVKHPNILQLVDVFVTRKEYFIFLELATGREVFDWILDQGYYSERDTS 123
            R    N + +   + HPN++Q  + + T    ++ +EL TG  + D +    +  E    
Sbjct: 1001 RPEVTNTVRMTHDISHPNVVQFHEWYETSNHLWLVVELCTGGSLADILAQDHHLPETSIR 822

Query: 124  NVVRQVLEAVAYLHSLKIVHRNLKLENLVYYNRLKNSKIV-ISDFHLAKLENGLIKE--- 179
            +    ++  + Y+HSL I+  +L+   ++    L  S ++  +DF L+K+E   ++E   
Sbjct: 821  DFGIHLVTGLHYIHSLGILFHDLRPSKVL----LDTSGVLKFADFGLSKVEGENLEELFF 654

Query: 180  ----------------------PCGTPEYLAPEVVGRQRYGRPVDCWAIGVIMYILLSGN 217
                                    G+P Y+APEV          D WA+G + Y + SG+
Sbjct: 653  KFAEAGDQWNIQSAEEMMKQVPTSGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFSGH 474

Query: 218  PPFYEEVEEDDYENHDKNLFRKILAGDYEFDSPYWDDISQAAK------DLVTRLMEVEQ 271
            PPF  E  +      DK L       + EF  P       +AK      +L+  L++ + 
Sbjct: 473  PPFLGETYDI---TKDKVL-------NKEFPLPKVKGSRLSAKPSPEFLNLLESLLQKDS 324

Query: 272  DQRITAEEAISHEWISGNAAS 292
             +R++    + H +  G  +S
Sbjct: 323  TRRLSWASLVKHAFWQGGLSS 261
>00392
          Length = 668

 Score = 66.6 bits (161), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 52/174 (29%), Positives = 86/174 (49%), Gaps = 8/174 (4%)
 Frame = +3

Query: 57  KRDGRKVRKAAKNEIGILKMVKHPNILQLVDVF-----VTRKEYFIFLELATGREVFDWI 111
           K+  +  R+  K E  +LK ++HPNI++  D +       RK   +  EL T   +  ++
Sbjct: 42  KKWNKAERQRFKEEAEMLKELQHPNIVRFFDYWEEHNHRNRKVIILVTELMTSGTLKTYL 221

Query: 112 LDQGYYSERDTSNVVRQVLEAVAYLHSLK--IVHRNLKLENLVYYNRLKNSKIVISDFHL 169
                 + +   N  RQVL+ + +LH+    ++HR+LK +N+       + KI   D  L
Sbjct: 222 KRFKKPNVKILKNWCRQVLKGLYFLHTRTPPVIHRDLKCDNIFITGPTGSVKI--GDLGL 395

Query: 170 AKLEN-GLIKEPCGTPEYLAPEVVGRQRYGRPVDCWAIGVIMYILLSGNPPFYE 222
           A L+N    K   GTPE++APE+   + Y   VD +A G+ M  + S   P+ E
Sbjct: 396 ATLKNQSFAKSVIGTPEFMAPEMY-EEHYDEAVDVYAFGMCMLEMASSEYPYSE 554
>26711
          Length = 405

 Score = 65.9 bits (159), Expect = 4e-11,   Method: Composition-based stats.
 Identities = 44/145 (30%), Positives = 76/145 (52%), Gaps = 6/145 (4%)
 Frame = -2

Query: 125 VVRQVLEAVAYLHSLKIVHRNLKLENLVYY-NRLKNSKIVISDFHLAKL----ENGLIKE 179
           VV+QVL+ + ++H+  +VH +LK  NL+   ++L + +++  DF LA+     +   +  
Sbjct: 401 VVKQVLDILQHVHAQGVVHMDLKPSNLLLSGDKLDSVQLI--DFGLARKLYPPQETFLNH 228

Query: 180 PCGTPEYLAPEVVGRQRYGRPVDCWAIGVIMYILLSGNPPFYEEVEEDDYENHDKNLFRK 239
             GTP + +PE +  +      D W +GV+ YILLSG  PF  +   +          +K
Sbjct: 227 --GTPGFTSPEALDVKPISTASDVWGVGVLAYILLSGQSPFQADSATES--------LKK 78

Query: 240 ILAGDYEFD-SPYWDDISQAAKDLV 263
               D+ FD  P + ++SQ AKD +
Sbjct: 77  TQTCDWSFDVCPSFSNMSQDAKDFI 3
>31885
          Length = 529

 Score = 65.1 bits (157), Expect = 7e-11,   Method: Compositional matrix adjust.
 Identities = 47/157 (29%), Positives = 83/157 (52%), Gaps = 7/157 (4%)
 Frame = -2

Query: 71  IGILKMVKHPNILQLVDVFVTRKEYFIFLELATGREVFDWILDQGYYSERDTSNVVRQVL 130
           + +L  + HP ++ L   F   ++ F+ ++L  G ++   +  +  + E      + Q+ 
Sbjct: 519 VDMLTRLDHPFLVNLWYAFQDEEDLFMVVDLFLGGDLRYHMQQEVSFREDCVKFYLCQLA 340

Query: 131 EAVAYLHSLKIVHRNLKLENLVYYNRLKNSKIVISDFHLA-KLENG-LIKEPCGTPEYLA 188
             + YL S KIVHR++K +N++     +     ++DF++A +LE+  L     GT  Y+A
Sbjct: 339 LVLDYLRSQKIVHRDIKPDNILLD---EQGHCHVTDFNIATQLEDDELATSTSGTRPYMA 169

Query: 189 PEVVG-----RQRYGRPVDCWAIGVIMYILLSGNPPF 220
           PEV G     R+ YG PVD W++GV ++ LL    PF
Sbjct: 168 PEVYGVAINERRGYGFPVDWWSLGVSLFELLKKRRPF 58
>00486
          Length = 797

 Score = 63.9 bits (154), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 33/95 (34%), Positives = 53/95 (55%)
 Frame = -2

Query: 181 CGTPEYLAPEVVGRQRYGRPVDCWAIGVIMYILLSGNPPFYEEVEEDDYENHDKNLFRKI 240
           CGT EY+APE++ R  +G+ VD W++G +MY +L+G+PPF  E        + K    KI
Sbjct: 775 CGTIEYMAPEILTRTGHGKAVDWWSLGALMYDMLTGSPPFTAE--------NRKKTIDKI 620

Query: 241 LAGDYEFDSPYWDDISQAAKDLVTRLMEVEQDQRI 275
           L G      PY   ++  A+ L+ +L+     +R+
Sbjct: 619 LKGKLNL-PPY---LTNEARGLIKKLLRKNPAERL 527
>18921
          Length = 697

 Score = 63.2 bits (152), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 51/206 (24%), Positives = 100/206 (48%), Gaps = 5/206 (2%)
 Frame = +2

Query: 22  DRYDLGQVIKTEEFCEIFRAKDKTTGKLHTCKKF-QKRDGRKVRKAAKNEIGILKMVKHP 80
           D +D+   +    +  +F++  K TG++   K+     D +++ K    EI I++     
Sbjct: 29  DVFDILGKLGEGSYGSVFKSLHKETGQVLAIKQVPVDTDLQEIIK----EISIMQQCDSK 196

Query: 81  NILQLVDVFVTRKEYFIFLELATGREVFDWI-LDQGYYSERDTSNVVRQVLEAVAYLHSL 139
            I++    +    + +I +E      V D + L      ER+ + ++   L+ + YLHS 
Sbjct: 197 YIVKYYGSYFKNTDLWIVMEYCGAGSVSDIMRLRNKTLVEREIATILYYTLKGLXYLHSR 376

Query: 140 KIVHRNLKLENLVYYNRLKNSKIVISDFHLA-KLENGLIKE--PCGTPEYLAPEVVGRQR 196
           + +HR++K  N++  N   ++K+  +DF +A +L + + K     GTP ++APEV+    
Sbjct: 377 RKIHRDIKAGNILLNNE-GHAKL--ADFGVAGQLTDTMAKRNTVIGTPYWMAPEVIQEIG 547

Query: 197 YGRPVDCWAIGVIMYILLSGNPPFYE 222
           Y    D W++G+    +  G PP  E
Sbjct: 548 YDCVADIWSLGITALEMAEGKPPVME 625
>29581
          Length = 1278

 Score = 61.6 bits (148), Expect = 7e-10,   Method: Compositional matrix adjust.
 Identities = 47/150 (31%), Positives = 80/150 (53%), Gaps = 8/150 (5%)
 Frame = -2

Query: 77   VKHPNILQLVDVFVTRKEYFIFLELATGREVFDWILDQ--GYYSERDTSNVVRQVLEAVA 134
            ++H NI+QL +V V +    +FL +    +    +LD     +SE     +V Q+L+ + 
Sbjct: 1184 LRHQNIVQLQEVVVGKSLDSLFLVMEYCEQDLASLLDNMPAPFSESQVKCIVLQLLKGLR 1005

Query: 135  YLHSLKIVHRNLKLENLVYYNRLKNSKIVISDFHLAKLENGLIKEPCGTPE-----YLAP 189
            YLH   I+HR+LK+ NL+  ++     + I+DF LA+   G  ++P  TP+     Y AP
Sbjct: 1004 YLHEAFIIHRDLKVSNLLMTDK---GCVKIADFGLAR-NYGKPQKPM-TPKVVTLWYRAP 840

Query: 190  EVV-GRQRYGRPVDCWAIGVIMYILLSGNP 218
            E++ G + +   +D W+ G I+  LL   P
Sbjct: 839  ELLFGSKTHSTAIDMWSAGCILGELLGHKP 750
>27546
          Length = 426

 Score = 61.6 bits (148), Expect = 7e-10,   Method: Composition-based stats.
 Identities = 37/109 (33%), Positives = 56/109 (51%)
 Frame = -1

Query: 63  VRKAAKNEIGILKMVKHPNILQLVDVFVTRKEYFIFLELATGREVFDWILDQGYYSERDT 122
           V+K    E+ IL  + HPNI+Q+  +     + FIF+  A   ++   I   G   E  T
Sbjct: 351 VKKFFPRELEILTRLDHPNIIQIHSILQRGPKIFIFMRYAEKGDMLSHIKKTGPIDEAQT 172

Query: 123 SNVVRQVLEAVAYLHSLKIVHRNLKLENLVYYNRLKNSKIVISDFHLAK 171
                Q+ +A+ YLHS  I HR+LK EN++   RL    + I+DF  A+
Sbjct: 171 KVWFFQMAKALQYLHSHDIAHRDLKCENILLSKRL---NVKIADFGFAR 34
>01756
          Length = 1858

 Score = 61.2 bits (147), Expect = 9e-10,   Method: Compositional matrix adjust.
 Identities = 50/202 (24%), Positives = 98/202 (48%), Gaps = 18/202 (8%)
 Frame = -3

Query: 35   FCEIFRAKDKTTGKLHTCKKF---QKRDGRKVRKAAKNEIGILKMVKHPNILQLVDVFVT 91
            F E+F+A+ K T ++   KK     +++G  +   A  EI IL+++ H N++ L+++  T
Sbjct: 1703 FGEVFKARCKKTKQVVAMKKVLMDNEKEGFPI--TALREIKILQLLNHENVVDLIEICST 1530

Query: 92   ------RKEYFIFLELATGREVFDWILDQG--YYSERDTSNVVRQVLEAVAYLHSLKIVH 143
                  R +   +L           +L      ++  +   V++Q++  + Y+H  KI+H
Sbjct: 1529 KATSANRYKSMFYLVFEFCEHDLAGLLSNMSVVFNLPEIKEVMKQLMNGLYYIHRNKILH 1350

Query: 144  RNLKLENLVYYNRLKNSKIVISDFHLAKLENGLIKEP------CGTPEYLAPE-VVGRQR 196
            R++K  N++     K   + ++DF LA+  +  +++P        T  Y  PE ++G + 
Sbjct: 1349 RDMKAANILI---TKQGVLKLADFGLARAFSVNLRQPNRYTNRVVTLWYRPPELLLGDRN 1179

Query: 197  YGRPVDCWAIGVIMYILLSGNP 218
            Y   +D W  G IM  + + NP
Sbjct: 1178 YSTAIDQWGAGCIMAEMWTRNP 1113
>06405
          Length = 1965

 Score = 58.5 bits (140), Expect = 7e-09,   Method: Compositional matrix adjust.
 Identities = 38/150 (25%), Positives = 72/150 (48%), Gaps = 6/150 (4%)
 Frame = +1

Query: 70  EIGILKMVKHPNILQLVDVFVTRKEYFIFLELATGREVFDWILDQGYYSERDTS--NVVR 127
           E  I+K +KHPN++QL+ V      ++I  E      + D++          T+   +  
Sbjct: 397 EAAIMKEMKHPNLVQLLGVCTREPPFYIVTEFMPHGNLLDYLRSSTREENGPTALMYMAT 576

Query: 128 QVLEAVAYLHSLKIVHRNLKLENLVYYNRLKNSKIVISDFHLAKL-ENGLIKEPCGTP-- 184
           Q+   +AYL +   +HR+L   N +  +   ++ + ++DF LA+L ++       G    
Sbjct: 577 QIASGMAYLETKNFIHRDLAARNCLVAD---SNMVKVADFGLARLMKDDTYTAHIGAKFP 747

Query: 185 -EYLAPEVVGRQRYGRPVDCWAIGVIMYIL 213
            ++ APE +   R+    D WA GV+++ L
Sbjct: 748 IKWTAPEGLAFNRFSTRSDIWAFGVLLWEL 837
>18663
          Length = 600

 Score = 57.4 bits (137), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 27/62 (43%), Positives = 40/62 (64%), Gaps = 1/62 (1%)
 Frame = +2

Query: 181 CGTPEYLAPEVVGRQRYGRPVDCWAIGVIMYILLSGNPPF-YEEVEEDDYENHDKNLFRK 239
           CGTP Y+APE++  + YG  VD WA+GV++Y +L+G  PF      E+  +N +  LF+ 
Sbjct: 11  CGTPNYIAPEILRGEDYGFSVDWWALGVLLYEMLAGRSPFDIAGASENPDQNTEDYLFQV 190

Query: 240 IL 241
           IL
Sbjct: 191 IL 196
>02638
          Length = 1490

 Score = 56.2 bits (134), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 30/102 (29%), Positives = 54/102 (52%)
 Frame = +1

Query: 182 GTPEYLAPEVVGRQRYGRPVDCWAIGVIMYILLSGNPPFYEEVEEDDYENHDKNLFRKIL 241
           GT  ++APEV+  + YGR  D W++G +M  + +  PP+       D  NH   +F+   
Sbjct: 22  GTIAFMAPEVLRGESYGRACDVWSVGCVMIEMCTCRPPW----NSHDISNHLALIFKIAS 189

Query: 242 AGDYEFDSPYWDDISQAAKDLVTRLMEVEQDQRITAEEAISH 283
           + D     P  +++S   +DL+ R +E + D R +A++ + H
Sbjct: 190 SVD---PPPIPENMSPPVRDLMLRCLEQDSDFRPSAKDLLMH 306
>27274
          Length = 396

 Score = 55.8 bits (133), Expect = 4e-08,   Method: Composition-based stats.
 Identities = 29/98 (29%), Positives = 56/98 (57%)
 Frame = -1

Query: 190 EVVGRQRYGRPVDCWAIGVIMYILLSGNPPFYEEVEEDDYENHDKNLFRKILAGDYEFDS 249
           E++  Q++G  VD W++G++++ LLSG+ PF  E        +   ++ +I+ G    D 
Sbjct: 375 ELLRGQQHGPTVDMWSLGILLHELLSGHVPFEPERGSRQMARNMMAVYAQIIRGSSR-DV 199

Query: 250 PYWDDISQAAKDLVTRLMEVEQDQRITAEEAISHEWIS 287
                +S    D + RL+++E  +R+T+++A SH WI+
Sbjct: 198 CDGLALSTHGADFLRRLVQLEDTKRLTSQQAFSHPWIA 85
>38560
          Length = 479

 Score = 55.5 bits (132), Expect = 5e-08,   Method: Compositional matrix adjust.
 Identities = 34/110 (30%), Positives = 56/110 (50%), Gaps = 3/110 (2%)
 Frame = -3

Query: 181 CGTPEYLAPEVV-GRQRYGRPVDCWAIGVIMYILLSGNPPFYEEVEEDDYENH--DKNLF 237
           CG+P Y APE++ G +  G   D W++GV++Y LL G  PF     +D+  +H   KN  
Sbjct: 402 CGSPAYAAPELISGLEYLGSEADIWSMGVLLYALLCGYLPF-----DDEKXSHL*QKNQK 238

Query: 238 RKILAGDYEFDSPYWDDISQAAKDLVTRLMEVEQDQRITAEEAISHEWIS 287
           RK        + P W  +S+    L+  +++ +   RIT    + H W++
Sbjct: 237 RKD-------EVPEW--LSEDTTKLLEGMLQTDPSHRITIRRLLDHHWLN 115
>04591
          Length = 1117

 Score = 55.5 bits (132), Expect = 6e-08,   Method: Compositional matrix adjust.
 Identities = 45/170 (26%), Positives = 85/170 (50%), Gaps = 18/170 (10%)
 Frame = -2

Query: 67   AKNEIGILKMVKHPNILQLVDVFVTRKE---------YFIFLELATGREVFDWILD---- 113
            A  EI IL+ ++H N++QL ++  T+           Y IF       E  D+ L     
Sbjct: 1080 ALREIKILQQLEHENVVQLQEICHTQAGPYNRYKSTFYLIF-------EYCDYDLAGLLN 922

Query: 114  --QGYYSERDTSNVVRQVLEAVAYLHSLKIVHRNLKLENLVYYNRLKNSKIVISDFHLAK 171
              +  +S  D  N++ Q+L  + Y+H+ +I+HR++K  N++     ++  + ++DF L++
Sbjct: 921  NLRVKFSLADKKNLMSQLLNGLFYIHTKQILHRDIKAANILLT---RDGVLKLADFGLSR 751

Query: 172  --LENGLIKEPCGTPEYLAPE-VVGRQRYGRPVDCWAIGVIMYILLSGNP 218
              +++  +     T  Y  PE ++G + YG  +D W +G IM  + S  P
Sbjct: 750  PWVKSKRLTNRVVTLWYRPPELLLGEREYGPEIDMWGVGCIMAEMWSRKP 601
>01718
          Length = 959

 Score = 55.1 bits (131), Expect = 7e-08,   Method: Compositional matrix adjust.
 Identities = 47/184 (25%), Positives = 90/184 (48%), Gaps = 8/184 (4%)
 Frame = +3

Query: 35  FCEIFRAKDKTTGKLHTCKKFQKRDGRKVRKAAKNEIGILKMVKHPNILQLVDVFVTRKE 94
           F E+F+   + TG++   K       R        E+ +L  ++H NIL+ + V V   +
Sbjct: 186 FSEVFKVTHRITGQVMALKMNTMTSNRH---NMLREVQLLNRLQHANILRFMGVCVHEGQ 356

Query: 95  YFIFLE-LATGR--EVFDWILDQGYYSERDTSNVVRQVLEAVAYLHSLKIVHRNLKLENL 151
                E + +G   ++ +   ++  +++R    +   +   + YLHS + +HR+L  +N+
Sbjct: 357 LHALTEYIPSGNLEQLLEKKDEELPWTQR--IQLTLGLARGLDYLHSTRFIHRDLTSKNI 530

Query: 152 VYYNRLKNS-KIVISDFHLA-KLENGLIKEP---CGTPEYLAPEVVGRQRYGRPVDCWAI 206
           +      +    VI+DF LA K+ + L KE     G+P ++APEV+    Y    D +++
Sbjct: 531 LIRREDNHGYHAVIADFGLATKIPDPLDKEKLPTVGSPYWMAPEVLNGHFYNERADLFSV 710

Query: 207 GVIM 210
           G+IM
Sbjct: 711 GIIM 722
>21433
          Length = 590

 Score = 54.7 bits (130), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 33/102 (32%), Positives = 53/102 (51%), Gaps = 1/102 (0%)
 Frame = +2

Query: 120 RDTSNVVRQVLEAVAYLHSLKIVHRNLKLENLVYYNRLKNSKIVISDFHLA-KLENGLIK 178
           + T+  + Q+  A+ Y H  K++HR++K ENL          + I+DF  +    +    
Sbjct: 167 KRTACYIYQLSSALEYCHYRKVIHRDIKPENL---LLGLKGDLKIADFGWSVHAPSSRRT 337

Query: 179 EPCGTPEYLAPEVVGRQRYGRPVDCWAIGVIMYILLSGNPPF 220
             CGT +YL PE+V  + +   VD W++GV+ Y  L G PP 
Sbjct: 338 TMCGTLDYLPPEMVEGKTHDENVDLWSLGVLCYEFLVGTPPL 463
>25019
          Length = 730

 Score = 41.2 bits (95), Expect(2) = 4e-07,   Method: Compositional matrix adjust.
 Identities = 19/53 (35%), Positives = 31/53 (58%), Gaps = 3/53 (5%)
 Frame = +3

Query: 158 KNSKIVISDFHLAK---LENGLIKEPCGTPEYLAPEVVGRQRYGRPVDCWAIG 207
           K+  + ++DF L K       +    CGT EY+APE++ R  +G+ VD W++G
Sbjct: 279 KDGHVKLTDFGLCKEAITGTRVTHTFCGTIEYMAPEILTRTGHGKAVDWWSLG 437

 Score = 30.8 bits (68), Expect(2) = 4e-07,   Method: Compositional matrix adjust.
 Identities = 21/73 (28%), Positives = 34/73 (46%)
 Frame = +1

Query: 203 CWAIGVIMYILLSGNPPFYEEVEEDDYENHDKNLFRKILAGDYEFDSPYWDDISQAAKDL 262
            W  G +MY +L+G+PPF  E        + K    KIL G      PY   ++  A+ L
Sbjct: 430 VW--GALMYDMLTGSPPFTAE--------NRKKTIDKILKGKLNL-PPY---LTNEARGL 567

Query: 263 VTRLMEVEQDQRI 275
           + +L+     +R+
Sbjct: 568 IKKLLRKNPAERL 606
>19301
          Length = 712

 Score = 52.0 bits (123), Expect = 5e-07,   Method: Compositional matrix adjust.
 Identities = 32/107 (29%), Positives = 53/107 (49%)
 Frame = +2

Query: 61  RKVRKAAKNEIGILKMVKHPNILQLVDVFVTRKEYFIFLELATGREVFDWILDQGYYSER 120
           +KVR   + +I  L+ + HPNI+    V      Y I +E     ++++ + D       
Sbjct: 392 KKVRDIKETDIRNLRKLNHPNIISFKGVCTQAPCYCIIMEYCPYGQLYEVLRDGKEIPPA 571

Query: 121 DTSNVVRQVLEAVAYLHSLKIVHRNLKLENLVYYNRLKNSKIVISDF 167
              +  +Q+   + YLHS KI+HR+LK  N++     KN  + ISDF
Sbjct: 572 LVLDWSKQIASGMNYLHSHKIIHRDLKSPNVLV---AKNDVVKISDF 703
>21808
          Length = 1011

 Score = 49.7 bits (117), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 39/153 (25%), Positives = 71/153 (46%), Gaps = 12/153 (7%)
 Frame = +1

Query: 70  EIGILKMVKHPNILQLVDVFVTRKEYFIFLELATGREVFDWILDQGYYSERDTS-NVVRQ 128
           E  I+K ++HP ++QL  V       FI  EL     + +++  +G   +     ++  Q
Sbjct: 82  EAQIMKKLRHPKLIQLYAVCTQDDPIFIITELMKNGSLLEFLQGKGRVLKLPALIDIGAQ 261

Query: 129 VLEAVAYLHSLKIVHRNLKLENLVYYNRLKNSKIVISDFHLAKLENGLIKE--------- 179
           +   +AYL S   +HR+L   N++  +   N+ + I+DF LA+    +IKE         
Sbjct: 262 IACGMAYLESQNYIHRDLAARNILVSD---NNTVKIADFGLAR----VIKEDEYEARVGA 420

Query: 180 --PCGTPEYLAPEVVGRQRYGRPVDCWAIGVIM 210
             P    ++ APE     R+    D W+ G+++
Sbjct: 421 RFPI---KWTAPEAANYNRFTIKSDVWSFGILL 510
>19094
          Length = 898

 Score = 49.7 bits (117), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 31/102 (30%), Positives = 58/102 (56%), Gaps = 3/102 (2%)
 Frame = +1

Query: 119 ERDTSNVVRQVLEAVAYLHSLKIVHRNLKLENLVYYNRLKNSKIVISDFHLA-KLENGLI 177
           ER+ + ++   L+ + YLHS + +HR++K  N++  N   ++K+  +DF +A +L + + 
Sbjct: 55  EREIATILYYTLKGL*YLHSRRKIHRDIKAGNILLNNE-GHAKL--ADFGVAGQLTDTMA 225

Query: 178 KE--PCGTPEYLAPEVVGRQRYGRPVDCWAIGVIMYILLSGN 217
           K     GTP ++APEV+    Y    D W++G+    +  GN
Sbjct: 226 KRNTVIGTPYWMAPEVIQEIGYDCVADIWSLGITALEMAEGN 351
>21418
          Length = 831

 Score = 48.9 bits (115), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 18/50 (36%), Positives = 35/50 (70%)
 Frame = +2

Query: 238 RKILAGDYEFDSPYWDDISQAAKDLVTRLMEVEQDQRITAEEAISHEWIS 287
           ++I +G Y+F  P W ++SQAAKDL+  ++ V+  +R+  E+ + ++WI+
Sbjct: 8   KRIRSGQYDFPDPEWTNVSQAAKDLIKGMLNVDPSKRLCIEDVLRNKWIA 157
>04138
          Length = 800

 Score = 48.1 bits (113), Expect = 9e-06,   Method: Compositional matrix adjust.
 Identities = 46/201 (22%), Positives = 83/201 (41%), Gaps = 44/201 (21%)
 Frame = +1

Query: 131 EAVAYLHSLKIVHRNLKLENLVYYNRLKNSKIVISDFHLAKLENGLIKEP------CGTP 184
           E + Y+H  KI+HR++K  N++     K   + ++DF LA+  +  +++P        T 
Sbjct: 46  ERLYYIHRNKILHRDMKAANILI---TKQGVLKLADFGLARAFSVNLRQPNRYTNRVVTL 216

Query: 185 EYLAPE-VVGRQRYGRPVDCWAIGVIMYILLSGNPPFYEEVEEDDY-------------- 229
            Y  PE ++G + Y   +D W  G IM  + + NP      E++                
Sbjct: 217 WYRPPELLLGDRNYSTAIDQWGAGCIMAEMWTRNPIMQGTTEQNQLTLITQLCGSITPEV 396

Query: 230 ---------------------ENHDKNLFRKILAGDYEFDSPYWDDISQAAKDLVTRLME 268
                                +N  ++ F +IL   Y               DL  RL++
Sbjct: 397 WPGVTQLSMYHQIKGALAAGRKNIIRDRFARILKDPYGL-------------DLFERLLK 537

Query: 269 VEQDQRITAEEAISHE--WIS 287
           ++  QRI+A+EA++H+  W+ 
Sbjct: 538 MDPSQRISADEALNHDFFWVG 600
>13212
          Length = 1067

 Score = 48.1 bits (113), Expect = 9e-06,   Method: Compositional matrix adjust.
 Identities = 44/189 (23%), Positives = 85/189 (44%), Gaps = 11/189 (5%)
 Frame = -1

Query: 117 YSERDTSNVVRQVLEAVAYLHSLKIVHRNLKLENLVYYNRLKNSKIVISDFHLAKLENGL 176
            +E     V  ++  A+ +LH   ++HR++K  N++      + ++ ++DF ++  +N  
Sbjct: 989 MTEAQICYVCHEMCMALDFLHRHHVIHRDIKAGNVLLTI---DGEVKLADFGVSA-KNTQ 822

Query: 177 IKEP----CGTPEYLAPEVVGRQR-----YGRPVDCWAIGVIMYILLSGNPPFYEEVEED 227
            ++      GTP ++APEVV  +      Y    D W++GV +       PP        
Sbjct: 821 TQQKRDTFIGTPYWMAPEVVLCETLKDTPYDFKADIWSLGVTLIEFAQIEPP-------- 666

Query: 228 DYENHDKNLFRKILAGDYE-FDSP-YWDDISQAAKDLVTRLMEVEQDQRITAEEAISHEW 285
           + E H   +  KI   D    + P  W   ++  KD + + +  + + R TA E + H +
Sbjct: 665 NKEMHPMRVLIKIHKSDPPTLEKPKKW---TKLFKDFIAKCLVKDPNLRPTAAELLEHPF 495

Query: 286 ISGNAASDK 294
           +    A+DK
Sbjct: 494 MKRATATDK 468
>07291
          Length = 833

 Score = 47.8 bits (112), Expect = 9e-06,   Method: Compositional matrix adjust.
 Identities = 29/108 (26%), Positives = 53/108 (49%), Gaps = 9/108 (8%)
 Frame = +1

Query: 127 RQVLEAVAYLHSLKIVHRNLKLENLVYYNRLKNSKIVISDFHLAKLENGLIKEPCGTPE- 185
           RQ+ + +AYL  +K+VHRNL   N +     ++ ++ +SD+ +      L  +   T + 
Sbjct: 70  RQIADGMAYLQEVKVVHRNLAARNCIV---TEDGRLQLSDYGVT---GSLFPQSYYTADD 231

Query: 186 --------YLAPEVVGRQRYGRPVDCWAIGVIMYILLSGNPPFYEEVE 225
                   ++APE +    +    D WA GV+++ LL+     Y +VE
Sbjct: 232 SPARDLVKWMAPETIDNFHFSSKSDVWAFGVVLWELLTRGITPYPDVE 375
>09007
          Length = 1440

 Score = 47.8 bits (112), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 40/174 (22%), Positives = 80/174 (45%), Gaps = 20/174 (11%)
 Frame = -1

Query: 58  RDGRKVRKAAKNEIGILKMVKHPNILQLVDVFVTR-KEYFIFLELATGREVFDWILDQGY 116
           +DG++  K    E  I++M+ H NI+++  V +    +  +  ELA  R + + + +   
Sbjct: 750 KDGQEFLK----ETAIMQMLDHENIVRVYGVVMDNGADIMLVTELAPMRSLLECVKEVSA 583

Query: 117 ---YSERDTSNVVRQVLEAVAYLHSLKIVHRNLKLENLVYYNRLKNSKIVISDFHLA--- 170
              +S     +  +QV + ++YL S ++VHR+L   N++ +++   SK+ ISD  ++   
Sbjct: 582 RVDFSVPRLCDFSQQVCDGMSYLESKRLVHRDLAARNILLFSK---SKVKISDVGVSGAL 412

Query: 171 -------------KLENGLIKEPCGTPEYLAPEVVGRQRYGRPVDCWAIGVIMY 211
                         L+N +         + APE      +    D WA GV+++
Sbjct: 411 GAGKEYYQSQQTIHLQNAV--------AWCAPESFRNLCFSSASDVWAFGVLLW 274
>04852
          Length = 1462

 Score = 47.0 bits (110), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 46/205 (22%), Positives = 86/205 (41%), Gaps = 28/205 (13%)
 Frame = +1

Query: 62  KVRKAAKNEIGILKMVKHPNILQLVDVFVTRKEYFIFLELATGREVFDWI---------- 111
           +V KA K      KM  H NI+  +         ++ +E A    + D++          
Sbjct: 94  QVMKAVK------KMGSHINIVNFLGCCTQGGPLWVIVEFAKNGNLRDFLESCRDGINGY 255

Query: 112 ------LDQGYYSERDTSNVVR---------QVLEAVAYLHSLKIVHRNLKLENLVYYNR 156
                  D G+Y++    +V+R         Q+   + +L S K +HR+L   N++    
Sbjct: 256 GKFVSPQDPGWYTKTPGGHVIRRKNLLSYAFQIARGMEFLASRKCIHRDLAARNVLV--- 426

Query: 157 LKNSKIVISDFHLAKLENGLIKEPCGT--PEYLAPEVVGRQRYGRPVDCWAIGVIMYILL 214
            +   + I+DF L++  +   K   G    +++APE +   RY    D W+ GV+++ + 
Sbjct: 427 TEEHVLKIADFGLSRTGDYYKKRSGGRLPVKWMAPEALFDMRYTTKSDVWSFGVVLWEIF 606

Query: 215 S-GNPPFYEEVEEDDYENHDKNLFR 238
           S G  P+     E+ Y     + +R
Sbjct: 607 SLGGMPYASIPNEELYSKLLDDAYR 681
>32957
          Length = 645

 Score = 47.0 bits (110), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 19/42 (45%), Positives = 29/42 (69%)
 Frame = +3

Query: 174 NGLIKEPCGTPEYLAPEVVGRQRYGRPVDCWAIGVIMYILLS 215
            G  +  CGT EY+APEV  R+ YG+ VD W +G++++ LL+
Sbjct: 27  GGRTRTFCGTREYMAPEVHERKEYGKEVDWWGLGILLHELLA 152
>20152
          Length = 445

 Score = 46.2 bits (108), Expect = 3e-05,   Method: Composition-based stats.
 Identities = 28/100 (28%), Positives = 50/100 (50%), Gaps = 1/100 (1%)
 Frame = +1

Query: 189 PEVVGRQRYGRP-VDCWAIGVIMYILLSGNPPFYEEVEEDDYENHDKNLFRKILAGDYEF 247
           PE++    Y  P VD W++GVI+Y+L+ G  PF E         +D      I+   Y+ 
Sbjct: 1   PEILLGDSYDAPAVDVWSLGVILYMLVVGEAPFQEA--------NDSETLTMIMDCRYQI 156

Query: 248 DSPYWDDISQAAKDLVTRLMEVEQDQRITAEEAISHEWIS 287
             P+   IS   +DL+ ++++ E   R +    ++H W++
Sbjct: 157 -PPH---ISHKCQDLIEKMLQREPVDRASLPHILAHPWLN 264
>20655
          Length = 1181

 Score = 45.4 bits (106), Expect = 6e-05,   Method: Compositional matrix adjust.
 Identities = 17/52 (32%), Positives = 33/52 (63%)
 Frame = +2

Query: 238 RKILAGDYEFDSPYWDDISQAAKDLVTRLMEVEQDQRITAEEAISHEWISGN 289
           ++I  G YEF  P W  +SQ AKDL+  ++  + D+R+  ++ ++ +W++ N
Sbjct: 8   KRIRNGQYEFPKPEWSRVSQDAKDLIRGMLCTDPDKRLNIKQVMASKWVADN 163
>19761
          Length = 473

 Score = 45.1 bits (105), Expect = 7e-05,   Method: Composition-based stats.
 Identities = 26/89 (29%), Positives = 44/89 (49%), Gaps = 5/89 (5%)
 Frame = -3

Query: 128 QVLEAVAYLHSLK--IVHRNLKLENLVYYNRLKNSKIVISDFHLAKLENG---LIKEPCG 182
           Q   A+ Y+H+    I+HR+LK +N+    +     + + D  LA+   G         G
Sbjct: 399 QTASALNYMHTHTPVILHRDLKPQNIYVTEK---GDVRLGDLGLARKLTGPADFATSQVG 229

Query: 183 TPEYLAPEVVGRQRYGRPVDCWAIGVIMY 211
           T  YL+PE++ +Q Y    D W++G + Y
Sbjct: 228 TIMYLSPEILSQQPYNSKSDIWSLGCVFY 142
>31489
          Length = 329

 Score = 44.7 bits (104), Expect = 1e-04,   Method: Composition-based stats.
 Identities = 27/87 (31%), Positives = 47/87 (54%), Gaps = 5/87 (5%)
 Frame = +3

Query: 71  IGILKMVKHPNILQLVDVFVTRKEYFIFLELATGREVFDWILDQGYYSERD-TSNVVR-- 127
           I ILK  KH NI+ + ++   +  Y  F ++    ++ +  L +  YS++  T   +R  
Sbjct: 3   IKILKHFKHDNIISIREILKPKDSYHDFKDIHVVFDLMESDLHRIIYSDQPLTEEHIRYF 182

Query: 128 --QVLEAVAYLHSLKIVHRNLKLENLV 152
             Q+L  + Y+HS  +VHR+LK  NL+
Sbjct: 183 LYQILRGLKYIHSANVVHRDLKPSNLL 263
>36002
          Length = 253

 Score = 44.3 bits (103), Expect = 1e-04,   Method: Composition-based stats.
 Identities = 20/51 (39%), Positives = 30/51 (58%)
 Frame = +1

Query: 236 LFRKILAGDYEFDSPYWDDISQAAKDLVTRLMEVEQDQRITAEEAISHEWI 286
           LF +I  G+Y F S  W  IS +AKDL+  L+  E  +R +A + + H W+
Sbjct: 58  LFNRIQDGNYFFPSMEWSAISSSAKDLIRHLLVREPRKRYSAADVLKHPWV 210
>12786
          Length = 460

 Score = 44.3 bits (103), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 30/119 (25%), Positives = 54/119 (45%), Gaps = 25/119 (21%)
 Frame = -3

Query: 127 RQVLEAVAYLHSLKIVHRNLKLENLVYYNRLKNSKIVISDFHLAKL----ENGLIKEP-C 181
           R++L AV  LH+  ++H +LK  N +    L    + + DF +A      +  ++K+   
Sbjct: 389 REMLRAVKALHNEGVIHSDLKPANFM----LVAGNLKLIDFGIANTLQQDKTSVLKDSRV 222

Query: 182 GTPEYLAPEVVG--------------------RQRYGRPVDCWAIGVIMYILLSGNPPF 220
           GTP Y++PE +                     + + G   D W++G I+Y ++ G  PF
Sbjct: 221 GTPSYMSPEAIMAACDDSADDSMEEDGHRTKPKYKVGVRSDVWSLGCILYNMVYGRTPF 45
>32000
          Length = 644

 Score = 43.9 bits (102), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 38/149 (25%), Positives = 68/149 (45%), Gaps = 20/149 (13%)
 Frame = -1

Query: 159 NSKIVISDFHLAKLENGLIK---EPCGTPEYLAPEVV-GRQRYGRPVDCWAIGVIMYILL 214
            +K+ I+DF LA++    ++       T  Y APE++ G + Y  PVD W++G I   ++
Sbjct: 581 TAKMKIADFGLARVFGLPVRTYTHEVITLWYRAPEILLGCRFYSVPVDIWSLGCIFVEMM 402

Query: 215 SGNPPFYEEVEEDDYENHDKNLF---RKILAG-----DYEFDSPYWD--------DISQA 258
           +    F  + E D      + L     K+  G     DY+   P W          +S+ 
Sbjct: 401 TRRALFPGDSEIDQLYRIFRTLGTPDEKVWPGVSKLPDYKPTFPKWPLKNLETVVSLSKV 222

Query: 259 AKDLVTRLMEVEQDQRITAEEAISHEWIS 287
             DL+ R++    ++RI+A  A+ H + +
Sbjct: 221 GLDLLKRMLTYNPNRRISARSAMRHPYFN 135
>29590
          Length = 320

 Score = 43.9 bits (102), Expect = 1e-04,   Method: Composition-based stats.
 Identities = 17/44 (38%), Positives = 29/44 (65%)
 Frame = +3

Query: 177 IKEPCGTPEYLAPEVVGRQRYGRPVDCWAIGVIMYILLSGNPPF 220
           I++  GTP+Y+APEV+  +      D W++GV+ Y++L+   PF
Sbjct: 45  IRDIIGTPDYVAPEVLDYEPLSIQTDMWSLGVLSYVMLTACSPF 176
>36481
          Length = 806

 Score = 43.5 bits (101), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 36/126 (28%), Positives = 59/126 (46%), Gaps = 17/126 (13%)
 Frame = +2

Query: 45  TTGKLHTCKKFQKRDG---------RKVRKAAKNEIGILKMVKHPN------ILQLVDVF 89
           T GK+  CK   K D           K R+AAK EI +L+ ++  +       +Q++D F
Sbjct: 398 TFGKVVQCKDLLKGDDIALKIIKNVDKYREAAKLEINVLEKLREKDPHAKHMCVQMLDWF 577

Query: 90  VTRKEYFIFLELATGREVFDWILDQGY--YSERDTSNVVRQVLEAVAYLHSLKIVHRNLK 147
                  I   +  G  VFD++ D  Y  Y      ++  Q+  AV +LH  ++ H +LK
Sbjct: 578 DYHGHVCISFHML-GLSVFDFLKDNSYGAYPIEQVRHISYQLCYAVNFLHENQLTHTDLK 754

Query: 148 LENLVY 153
            EN+++
Sbjct: 755 PENILF 772
>28638
          Length = 1458

 Score = 42.4 bits (98), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 30/101 (29%), Positives = 51/101 (50%), Gaps = 2/101 (1%)
 Frame = -1

Query: 122 TSNVVRQVLEAVAYLHS--LKIVHRNLKLENLVYYNRLKNSKIVISDFHLAKLENGLIKE 179
           T    +Q+  A+ +L +  + I+H +LK EN++  N  K S I I DF  +      I +
Sbjct: 831 TRKFAQQLCTALLFLATPEMNIIHCDLKPENILLCNP-KRSAIKIVDFGSSCQLGQRIYQ 655

Query: 180 PCGTPEYLAPEVVGRQRYGRPVDCWAIGVIMYILLSGNPPF 220
              +  Y +PEV+    Y   +D W++G I+  + +G PP 
Sbjct: 654 YIQSRFYRSPEVLLGVPYDLAIDMWSLGCILVEMHTGEPPL 532
>31120
          Length = 439

 Score = 41.2 bits (95), Expect = 0.001,   Method: Composition-based stats.
 Identities = 25/85 (29%), Positives = 41/85 (48%)
 Frame = +1

Query: 202 DCWAIGVIMYILLSGNPPFYEEVEEDDYENHDKNLFRKILAGDYEFDSPYWDDISQAAKD 261
           D W++GVI++I+L+G  PF       D  N +K L     +  Y F     D +S  A+ 
Sbjct: 40  DAWSLGVILFIMLNGKMPF-------DDSNLNK-LLEDQRSKKYSFRRKLQDLVSPNARS 195

Query: 262 LVTRLMEVEQDQRITAEEAISHEWI 286
            V+ L+E     R    E ++ +W+
Sbjct: 196 TVSVLLEPNSAMRWDLNEVLNCQWL 270
>17722
          Length = 680

 Score = 40.0 bits (92), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 26/80 (32%), Positives = 40/80 (50%)
 Frame = -3

Query: 201 VDCWAIGVIMYILLSGNPPFYEEVEEDDYENHDKNLFRKILAGDYEFDSPYWDDISQAAK 260
           VD W  GV+MY ++ G  PFY         +HD  LF  IL  + +F      ++S+ AK
Sbjct: 678 VDWWGTGVVMYEMMCGRLPFYN-------RDHDV-LFELILLQNVKFPR----NLSEEAK 535

Query: 261 DLVTRLMEVEQDQRITAEEA 280
            L++ L+     +R+   EA
Sbjct: 534 TLLSGLLAKNPKRRLGGSEA 475
>01966
          Length = 1735

 Score = 40.0 bits (92), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 36/149 (24%), Positives = 61/149 (40%), Gaps = 19/149 (12%)
 Frame = -3

Query: 193  GRQRYGRPVDCWAIGVIMYILLSGNPPFYEEVEEDDYENHDKNL----------FRKILA 242
            G  +Y  PVD W+IG I   +L   P F  + E D      + +          F K+ A
Sbjct: 1187 GASKYSTPVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIFRIIGTPTEQTWPEFHKLPA 1008

Query: 243  GDYEFDSPYWD---------DISQAAKDLVTRLMEVEQDQRITAEEAISHEWISGNAASD 293
             +  F  P W          D+     DL+ R ++ +  QRI+ ++ + H +      S 
Sbjct: 1007 FNGMF--PLWKEGKLSETLTDLDSLGLDLIERTLKCDPAQRISCKKMLQHAYFLNVDTSV 834

Query: 294  KNIKDGVCAQIEKNFARAKWKKAVRVTTL 322
            K +   V +  +    R K+K+ +R  T+
Sbjct: 833  KPV--DVPSPEQS*STRLKYKETLRTKTI 753
>14116
          Length = 1017

 Score = 37.7 bits (86), Expect = 0.010,   Method: Compositional matrix adjust.
 Identities = 37/154 (24%), Positives = 69/154 (44%), Gaps = 11/154 (7%)
 Frame = -1

Query: 73  ILKMVKHPNILQLVDVFVTRKEY-FIFLELATGREVFDWILD-QGYYSERDTSNVVRQVL 130
           I+K   H N+L L+ + +   +   + L      ++  +I D Q   + +D       + 
Sbjct: 468 IMKDFHHSNVLTLIGICLNLDDMPLVVLPFMKHGDLLTYIRDDQHQPTIKDLIMYGVDIA 289

Query: 131 EAVAYLHSLKIVHRNLKLENLVYYNRLKNSKIVISDFHLAK---------LENGLIKEPC 181
             + YL  LK VHR+L   N +     ++  + ++DF LA+          EN   K P 
Sbjct: 288 RGMDYLAGLKFVHRDLAARNCMLD---EDFHVKVADFGLARDIYEKEYYSSENKKAKLPV 118

Query: 182 GTPEYLAPEVVGRQRYGRPVDCWAIGVIMYILLS 215
              +++A E + +  Y    D W+ GV+++ LL+
Sbjct: 117 ---KWMALESLEKGNYDSKTDVWSYGVVLWELLT 25
>11185
          Length = 473

 Score = 37.0 bits (84), Expect = 0.019,   Method: Composition-based stats.
 Identities = 28/116 (24%), Positives = 50/116 (43%), Gaps = 26/116 (22%)
 Frame = +1

Query: 128 QVLEAVAYLHSLKIVHRNLKLENLVYYNRLKNSKIV-ISDFHLAKLENGLIKE------- 179
            ++  + Y+HSL I+  +L+   ++    L  S ++  +DF L+K+E   ++E       
Sbjct: 25  HLVTGLHYIHSLGILFHDLRPSKVL----LDTSGVLKFADFGLSKVEGENLEELFFKFAE 192

Query: 180 ------------------PCGTPEYLAPEVVGRQRYGRPVDCWAIGVIMYILLSGN 217
                               G+P Y+APEV          D WA+G + Y + SG+
Sbjct: 193 AGDQWNIQSAEEMMKQVPTSGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFSGS 360
>07940
          Length = 1336

 Score = 36.6 bits (83), Expect = 0.023,   Method: Compositional matrix adjust.
 Identities = 33/124 (26%), Positives = 57/124 (45%), Gaps = 12/124 (9%)
 Frame = -3

Query: 120 RDTSNVVRQVLEAVAYLHSLKIVHRNLKLENLVYYNRLKNSKIVISDFHLA--------- 170
           +D  +   QV   + YL S + +HR+L   N++     +   + I+DF L          
Sbjct: 347 KDLISYAYQVARGMEYLASKQCIHRDLAARNVLV---AEEYVLKIADFGLTRNLQQFDYY 177

Query: 171 -KLENGLIKEPCGTPEYLAPEVVGRQRYGRPVDCWAIGVIMY--ILLSGNPPFYEEVEED 227
            K  +G  + P    +++APE +  ++Y    D W+ GV+++    L GNP  Y  V  +
Sbjct: 176 RKTTDG--RLPV---KWMAPEALFDRKYTSKSDVWSYGVLLWEIFTLGGNP--YPSVPVE 18

Query: 228 DYEN 231
           D  N
Sbjct: 17  DLFN 6
>01106
          Length = 878

 Score = 36.6 bits (83), Expect = 0.026,   Method: Compositional matrix adjust.
 Identities = 30/121 (24%), Positives = 59/121 (48%), Gaps = 19/121 (15%)
 Frame = +3

Query: 51  TCKKFQK----RDGRKVRKAAKNEIGILKMVKHPNI--------LQLVDVF----VTRKE 94
           TCK+F      +  +   + A +E+ +LK V+  ++        +QL+D F    V    
Sbjct: 387 TCKRFVALKVVKSAQHYTETALDEVKLLKCVRESDVADPARAKCVQLLDDFKISGVNGTH 566

Query: 95  YFIFLELATGREVFDWILDQGYYSE--RDTSNVVRQVLEAVAYLHS-LKIVHRNLKLENL 151
             +  E+  G  +   I+   Y      +   ++RQVLE ++Y+H+  +I+H ++K EN+
Sbjct: 567 VAMVFEV-LGYNLLKLIIRSNYQGIPIHNVKLIIRQVLEGLSYMHAKCRIIHTDIKPENI 743

Query: 152 V 152
           +
Sbjct: 744 L 746
>17300
          Length = 480

 Score = 36.6 bits (83), Expect = 0.027,   Method: Compositional matrix adjust.
 Identities = 26/106 (24%), Positives = 49/106 (46%), Gaps = 10/106 (9%)
 Frame = +1

Query: 132 AVAYLHSLKIVHRNLKLENLVYYNRLKNSKIV--ISDFHLAK------LENGLIKEPCGT 183
            +  L  +  VHR+L   N+     L N  +V  ++DF L++       E     +    
Sbjct: 10  GMGXLADMGYVHRDLAARNI-----LVNEILVCKVADFGLSREIESDTTEGAYTTKGGKI 174

Query: 184 P-EYLAPEVVGRQRYGRPVDCWAIGVIMYILLS-GNPPFYEEVEED 227
           P  + APE +  +++    D W+ GV+M+ ++S G  P++    +D
Sbjct: 175 PVRWTAPEAIAYRKFTSASDVWSFGVVMWEVMSYGERPYWNWSNQD 312
>26009
          Length = 886

 Score = 35.4 bits (80), Expect = 0.052,   Method: Compositional matrix adjust.
 Identities = 12/33 (36%), Positives = 27/33 (81%)
 Frame = +3

Query: 120 RDTSNVVRQVLEAVAYLHSLKIVHRNLKLENLV 152
           R+  +V++Q++ A+ ++HS ++VHR++K EN++
Sbjct: 711 REAKSVMKQLVSALDFMHSKQLVHRDIKPENVL 809
>03508
          Length = 1463

 Score = 34.7 bits (78), Expect = 0.082,   Method: Compositional matrix adjust.
 Identities = 23/97 (23%), Positives = 53/97 (54%), Gaps = 3/97 (3%)
 Frame = +1

Query: 117 YSERDTSNVVRQVLEAVAYLHSLKIVHRNLKLENLVYYNRLKNSKIVISDFHLAKLEN-G 175
           +++ D    + ++++A+ + HS+ I+HR++K  N++  +  +N K+ + D+ LA+  + G
Sbjct: 862 FTDYDIRFYLYELMKALDFCHSMGIMHRDVKPHNVMIDH--ENKKLRLIDWGLAEFYHPG 1035

Query: 176 LIKEPCGTPEYL-APE-VVGRQRYGRPVDCWAIGVIM 210
           +         Y   PE ++  Q Y   +D W++G + 
Sbjct: 1036MEYNVRVASRYFKGPELLLDYQMYDYSLDMWSLGCMF 1146
>18401
          Length = 463

 Score = 34.3 bits (77), Expect = 0.11,   Method: Composition-based stats.
 Identities = 15/38 (39%), Positives = 21/38 (55%)
 Frame = -3

Query: 183 TPEYLAPEVVGRQRYGRPVDCWAIGVIMYILLSGNPPF 220
           T  Y APEV+    +  P D W++G IM+ L +G   F
Sbjct: 443 TRHYRAPEVILELGWSHPCDVWSVGCIMFELYTGYTLF 330
>03294
          Length = 1684

 Score = 34.3 bits (77), Expect = 0.13,   Method: Compositional matrix adjust.
 Identities = 34/143 (23%), Positives = 57/143 (39%), Gaps = 19/143 (13%)
 Frame = -1

Query: 199  RPVDCWAIGVIMYILLSGNPPFYEEVEEDDYENHDKNL----------FRKILAGDYEFD 248
             PVD W+IG I   +L   P F  + E D      + +          F K+ A +  F 
Sbjct: 1678 HPVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIFRIIGTPTEQTWPEFHKLPAFNGMF- 1502

Query: 249  SPYWD---------DISQAAKDLVTRLMEVEQDQRITAEEAISHEWISGNAASDKNIKDG 299
             P W          D+     DL+ R ++ +  QRI+ ++ + H +      S K +   
Sbjct: 1501 -PLWKEGKLSETLTDLDSLGLDLIERTLKCDPAQRISCKKMLQHAYFLNVDTSVKPV--D 1331

Query: 300  VCAQIEKNFARAKWKKAVRVTTL 322
            V +       R K+K+ +R  T+
Sbjct: 1330 VPSPEHS*STRLKYKETLRTKTI 1262
>37063
          Length = 455

 Score = 33.5 bits (75), Expect = 0.22,   Method: Composition-based stats.
 Identities = 15/40 (37%), Positives = 24/40 (60%), Gaps = 5/40 (12%)
 Frame = -2

Query: 180 PCGTPEYLAPEVVGRQ-----RYGRPVDCWAIGVIMYILL 214
           P G+ EY+APEVV         Y +  D W++G+I+ +L+
Sbjct: 328 PVGSAEYMAPEVVDAWVGESFSYDKRCDMWSLGIIL*VLV 209
>00715
          Length = 1788

 Score = 32.7 bits (73), Expect = 0.40,   Method: Compositional matrix adjust.
 Identities = 44/208 (21%), Positives = 86/208 (41%), Gaps = 40/208 (19%)
 Frame = +1

Query: 53  KKFQKRDG--RKVRKAAKNEIGILKM-VKHPNILQLVDVFVTRK---------EYFIFLE 100
           K + KR    R +R++  NE+   +  ++H N++ ++      +         EY   L 
Sbjct: 16  KIYHKRSSNPRALRQSYSNELLAFRCGLRHVNVVSILGATSLHRFEDGAWLAMEYVGPLN 195

Query: 101 LATGREVFDWILDQGYYSERDTS---NVVRQVLEAVAYLHSLKIVHRNLKLENLVYYNRL 157
           L T       IL+  +  + D+S   ++  Q+   + YLHS+ IVH +LK  N +     
Sbjct: 196 LQT-------ILND-HQQDIDSSMRLSLALQMARGLHYLHSINIVHLDLKPANCLL---T 342

Query: 158 KNSKIVISDF-------------------------HLAKLENGLIKEPCGTPEYLAPEVV 192
           ++ K+ I+DF                          L  ++     E  GT  Y APE++
Sbjct: 343 RDLKLRIADFGCCHQLTPTGLDMGEREGGMAGNELELTPVQGAWKNELAGTLAYRAPELL 522

Query: 193 GRQRYGRPVDCWAIGVIMYILLSGNPPF 220
              +     D +++G+ ++ + +   P+
Sbjct: 523 KGLQPSVRSDVYSLGITLWQMCTRQGPY 606
>22644
          Length = 1600

 Score = 32.0 bits (71), Expect = 0.53,   Method: Compositional matrix adjust.
 Identities = 17/34 (50%), Positives = 21/34 (61%)
 Frame = +1

Query: 402 DGSATPATDGSVTPATDGSITPATDGSVTPATDR 435
           DGS T   DGS+T   DGS T   +GS+TP + R
Sbjct: 160 DGSWTSRRDGSMTSKRDGSWTSKQEGSMTPWSPR 261
>06358
          Length = 1517

 Score = 32.0 bits (71), Expect = 0.65,   Method: Compositional matrix adjust.
 Identities = 39/197 (19%), Positives = 86/197 (43%), Gaps = 28/197 (14%)
 Frame = +3

Query: 54  KFQKRDGRKVRKAAKNEIGILKMVKHPNILQLVDVFVTRKEYFIFL-------------E 100
           ++ +RD   + +  +  +  L  ++HP IL +++     +E   F              +
Sbjct: 126 RYSRRDREAIVEVLRVGVQQLTKLRHPKILAVINPLEESRETLAFATEPVFASLANVLGD 305

Query: 101 LATGREVFDWILDQGYYSERDTSNVVRQVLEAVAYLHS-LKIVHRNLKLENLVYYNRLKN 159
           L++   V   + D   Y + +  + + QV EA+ +LH+  K++HRN+  E  +   +L +
Sbjct: 306 LSSIXTVPKELQDYQLY-DVEIKHGLLQVTEALGFLHNDAKMMHRNVCPEA-IMLTKLGS 479

Query: 160 SKIVISDFHLAKLENGLIK------------EPCGTP--EYLAPEVVGRQRYGRPVDCWA 205
            K+   +F +   +                  P   P  +++APE V   + G   D ++
Sbjct: 480 WKLAGYEFCVRSSDPQSTDPSYPFYEWRSDIAPVTQPHLDFMAPEYVLTMQCGTGSDMFS 659

Query: 206 IGVIMYILLSGNPPFYE 222
           +G+++Y + +   P +E
Sbjct: 660 LGLLVYSVFAKGKPLFE 710
>03106
          Length = 2384

 Score = 31.2 bits (69), Expect = 0.93,   Method: Compositional matrix adjust.
 Identities = 31/129 (24%), Positives = 49/129 (37%), Gaps = 4/129 (3%)
 Frame = +2

Query: 202 DCWAIGVIMYILLSGNPPFYEEVEEDDYENHDKNLFRKILAGDYEFDSPYWDDISQAAKD 261
           D WA G + Y +   + PFY  ++   Y  HD       L G          D  +    
Sbjct: 32  DVWAAGAVAYEIFGASNPFYSRLDSACYSQHD----LPSLPG----------DTPEGVVR 169

Query: 262 LVTRLMEVEQDQRITAEEAISHEWISGNAASDKNIKDGVCAQIEKNFARAK----WKKAV 317
           LVT ++E +  QR +A  A +   +   A S  +       Q      R K    W + V
Sbjct: 170 LVTSMLERDPAQRPSAVVAATAMHLFLWAPSHMHPLTNHLPQHYNPLWRCKEIYHWLEQV 349

Query: 318 RVTTLMKRL 326
            + T+ +R+
Sbjct: 350 TMETVCQRV 376
>37602
          Length = 804

 Score = 31.2 bits (69), Expect = 0.98,   Method: Compositional matrix adjust.
 Identities = 18/66 (27%), Positives = 35/66 (53%)
 Frame = -1

Query: 87  DVFVTRKEYFIFLELATGREVFDWILDQGYYSERDTSNVVRQVLEAVAYLHSLKIVHRNL 146
           D ++ R++ +I +E   G  + D     G  +E   + V R+ L+ + YLH    +HR++
Sbjct: 318 DSYLRREKLWIAMEYCGGGSMQDIYHVTGPLTEPQIAFVCRETLKGLHYLHRRGKMHRDI 139

Query: 147 KLENLV 152
           K  N++
Sbjct: 138 KGANIL 121
>21800
          Length = 855

 Score = 30.4 bits (67), Expect = 1.7,   Method: Compositional matrix adjust.
 Identities = 13/29 (44%), Positives = 22/29 (75%), Gaps = 1/29 (3%)
 Frame = +2

Query: 125 VVRQVLEAVAYLHS-LKIVHRNLKLENLV 152
           ++RQVLE + YLH+   I+H ++K EN++
Sbjct: 647 IIRQVLEGLNYLHAKCNIIHTDIKPENIL 733
>18996
          Length = 491

 Score = 30.0 bits (66), Expect = 2.2,   Method: Composition-based stats.
 Identities = 20/79 (25%), Positives = 38/79 (48%), Gaps = 5/79 (6%)
 Frame = +2

Query: 142 VHRNLKLENLVYYNRLKNSKIVISDFHLAKLENGL-----IKEPCGTPEYLAPEVVGRQR 196
           +HR+L   N++    +  S + ISDF LA+  N       I +     ++ +PE +   +
Sbjct: 2   IHRDLAARNIL----VDRSCVKISDFGLAQFANADGYYYGISQRDIPIKWYSPEAIETCK 169

Query: 197 YGRPVDCWAIGVIMYILLS 215
           +    D W+ GV ++ + S
Sbjct: 170 FSSYSDVWSYGVTLFEMFS 226
>32473
          Length = 1077

 Score = 29.6 bits (65), Expect = 3.4,   Method: Compositional matrix adjust.
 Identities = 12/23 (52%), Positives = 14/23 (60%)
 Frame = +2

Query: 77  VKHPNILQLVDVFVTRKEYFIFL 99
           V HPN   +V  F   KEYF+FL
Sbjct: 440 VIHPNFAAMVSAFKAFKEYFVFL 508
>17516
          Length = 453

 Score = 29.3 bits (64), Expect = 4.2,   Method: Composition-based stats.
 Identities = 13/36 (36%), Positives = 24/36 (66%), Gaps = 1/36 (2%)
 Frame = -3

Query: 182 GTPEYLAPEVVGRQ-RYGRPVDCWAIGVIMYILLSG 216
           GTP Y+APEV+ ++ +Y    D +++ +I++ L  G
Sbjct: 433 GTPVYMAPEVLLQKGQYDMKADVYSLAIILWELWYG 326
>17253
          Length = 483

 Score = 28.5 bits (62), Expect = 7.6,   Method: Composition-based stats.
 Identities = 24/115 (20%), Positives = 52/115 (45%), Gaps = 13/115 (11%)
 Frame = -1

Query: 70  EIGIL-KMVKHPNILQLVDVFVTRKEYFIFLELATGREVFDWIL----DQGYY------- 117
           E+ I+ K+ +HPN++  +          I +E     ++  ++     D+  +       
Sbjct: 399 ELSIMRKLPRHPNVVSFMGCCTMSDPALILMEFCCHGDLLSFLRKRRPDRTVFLTSTAND 220

Query: 118 -SERDTSNVVRQVLEAVAYLHSLKIVHRNLKLENLVYYNRLKNSKIVISDFHLAK 171
            + RD  +    V   +A++ + KIVHR++   N++   R   +   +SDF L++
Sbjct: 219 LTARDFFSFALHVARGMAHVANNKIVHRDVAARNVLISER---NVCKVSDFGLSR 64
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6755252|ref|NP_035351.1| purine rich element binding
protein B [Mus musculus]
         (324 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

15221                                                                 154   4e-38
>15221
          Length = 1217

 Score =  154 bits (390), Expect = 4e-38,   Method: Compositional matrix adjust.
 Identities = 88/217 (40%), Positives = 120/217 (55%), Gaps = 6/217 (2%)
 Frame = -1

Query: 80   GSKSRLTLSMAVAAEFRDSLGDFIEHYAQLGPSSPEQLXXXXXXXXXXXXXLKSEFLVRE 139
            G KSRL L+M+ AAEFRD L DF EHYA LGP++ E               LKSE +V++
Sbjct: 1217 GKKSRLLLAMSSAAEFRDYLTDFTEHYASLGPTNTES--------PPEDGKLKSETIVKD 1062

Query: 140  NRKYYLDLKENQRGRFLR------IRQTVNRXXXXXXXXXXXXXLQSGQTIALPAQGLIE 193
            NR+YYLDLKENQRGRFLR      + QT+ R                   IA+PAQG+IE
Sbjct: 1061 NRRYYLDLKENQRGRFLRVVCYEQVSQTIPRGGPRSQ-------------IAIPAQGMIE 921

Query: 194  FRDALAKLIDDYXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTSITVDSKRFFFDVGCNKY 253
            FRDAL +L+D++                              S+ V++K F+FDVG N+ 
Sbjct: 920  FRDALTELLDEFGTDDQEPQNELPESR---------------SMRVENKMFYFDVGSNRR 786

Query: 254  GVFLRVSEVKPSYRNAITVPFKAWGKFGGAFCRYADE 290
            GV+LRVSEV+ ++R A+T+P ++W +F      + D+
Sbjct: 785  GVYLRVSEVRNNFRTAVTIPERSWARFRDVLSEFVDK 675

 Score = 62.0 bits (149), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 40/169 (23%), Positives = 76/169 (44%), Gaps = 7/169 (4%)
 Frame = -1

Query: 42   ETQELASKRLDIQNKRFYLDVKQNAKGRFLKIA-------EVGAGGSKSRLTLSMAVAAE 94
            E  +L S+ +   N+R+YLD+K+N +GRFL++         +  GG +S++ +      E
Sbjct: 1100 EDGKLKSETIVKDNRRYYLDLKENQRGRFLRVVCYEQVSQTIPRGGPRSQIAIPAQGMIE 921

Query: 95   FRDSLGDFIEHYAQLGPSSPEQLXXXXXXXXXXXXXLKSEFLVRENRKYYLDLKENQRGR 154
            FRD+L + ++ +         +L              +S  +  EN+ +Y D+  N+RG 
Sbjct: 920  FRDALTELLDEFGTDDQEPQNELP-------------ESRSMRVENKMFYFDVGSNRRGV 780

Query: 155  FLRIRQTVNRXXXXXXXXXXXXXLQSGQTIALPAQGLIEFRDALAKLID 203
            +LR+ +  N                    + +P +    FRD L++ +D
Sbjct: 779  YLRVSEVRNNFRT---------------AVTIPERSWARFRDVLSEFVD 678

 Score = 41.2 bits (95), Expect = 6e-04,   Method: Compositional matrix adjust.
 Identities = 24/67 (35%), Positives = 41/67 (61%), Gaps = 2/67 (2%)
 Frame = -1

Query: 40  EQETQ-ELA-SKRLDIQNKRFYLDVKQNAKGRFLKIAEVGAGGSKSRLTLSMAVAAEFRD 97
           +QE Q EL  S+ + ++NK FY DV  N +G +L+++EV     ++ +T+     A FRD
Sbjct: 875 DQEPQNELPESRSMRVENKMFYFDVGSNRRGVYLRVSEV-RNNFRTAVTIPERSWARFRD 699

Query: 98  SLGDFIE 104
            L +F++
Sbjct: 698 VLSEFVD 678
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31980840|ref|NP_059078.2| RAB11a, member RAS oncogene
family [Mus musculus]
         (216 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

08428                                                                 152   7e-38
33374                                                                 119   2e-34
34468                                                                 129   6e-31
14456                                                                 120   4e-28
26083                                                                 108   2e-24
17511                                                                 107   5e-24
05468                                                                 104   3e-23
33794                                                                 103   7e-23
01398                                                                 101   2e-22
07465                                                                  99   1e-21
32723                                                                  93   9e-20
13901                                                                  91   4e-19
11257                                                                  87   4e-18
33380                                                                  86   2e-17
01972                                                                  71   3e-17
13750                                                                  83   7e-17
19006                                                                  78   3e-15
30760                                                                  77   6e-15
01095                                                                  74   5e-14
11728                                                                  74   5e-14
07580                                                                  74   5e-14
35581                                                                  74   6e-14
12339                                                                  70   5e-13
26536                                                                  69   2e-12
34359                                                                  69   2e-12
13745                                                                  68   3e-12
19656                                                                  66   1e-11
00858                                                                  66   1e-11
09204                                                                  65   2e-11
00552                                                                  65   3e-11
27191                                                                  63   8e-11
14119                                                                  62   2e-10
29380                                                                  61   3e-10
34597                                                                  59   3e-10
25618                                                                  58   4e-09
10708                                                                  45   3e-08
14775                                                                  54   3e-08
24619                                                                  53   8e-08
19046                                                                  53   9e-08
31291                                                                  50   7e-07
09827                                                                  46   1e-05
12443                                                                  43   9e-05
08153                                                                  41   3e-04
25796                                                                  39   0.002
10862                                                                  38   0.003
33605                                                                  37   0.009
31932                                                                  35   0.021
22318                                                                  27   5.7  
11062                                                                  27   7.5  
06883                                                                  26   9.4  
>08428
          Length = 1109

 Score =  152 bits (385), Expect = 7e-38,   Method: Compositional matrix adjust.
 Identities = 78/183 (42%), Positives = 113/183 (61%)
 Frame = -3

Query: 13   KVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIQVDGKTIKAQIWDTAGQER 72
            KV L+GDSGVGKS+++ RF    +    +STIG  F ++S+ VDG   + QIWDTAGQE+
Sbjct: 1065 KVCLLGDSGVGKSSIVLRFVTGSYRPSQESTIGASFMSKSLVVDGAGYRFQIWDTAGQEK 886

Query: 73   YRAITSAYYRGAVGALLVYDIAKHLTYENVERWLKELRDHADSNIVIMLVGNKSDLRHLR 132
            +RA+   YYRGA  A++VYD+ +  T+++V+ W++ELR     NIV+ + GNK DL  LR
Sbjct: 885  FRALAPMYYRGAAAAVIVYDVTRPRTFKSVKSWIQELRSFGPPNIVLAIAGNKCDLEELR 706

Query: 133  AVPTDEARAFAEKNGLSFIETSALDSTNVEAAFQTILTEIYRIVSQKQMSDRRENDMSPS 192
             V   +A+ +A      F ETSA+ + NVE  F    TE+ R +  +      E++  PS
Sbjct: 705  EVVEKDAQEYASSISAIFGETSAMTAVNVEEMF----TELARQLPPE------EDNPHPS 556

Query: 193  NNV 195
            N V
Sbjct: 555  NTV 547
>33374
          Length = 489

 Score =  119 bits (298), Expect(2) = 2e-34,   Method: Compositional matrix adjust.
 Identities = 57/114 (50%), Positives = 79/114 (69%)
 Frame = +1

Query: 48  FATRSIQVDGKTIKAQIWDTAGQERYRAITSAYYRGAVGALLVYDIAKHLTYENVERWLK 107
           F T+++ +D  T+K +IWDTAGQERY ++   YYRGA  A++VYDI    T+   + W+K
Sbjct: 139 FLTQTVCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNQDTFGRAKTWVK 318

Query: 108 ELRDHADSNIVIMLVGNKSDLRHLRAVPTDEARAFAEKNGLSFIETSALDSTNV 161
           EL+  A  NIVI L GNK+DL + R V  +EA+A+AE+N L F+ETSA  + NV
Sbjct: 319 ELQRQASPNIVIALAGNKADLANKRMVEFEEAQAYAEENSLLFMETSAKTAMNV 480

 Score = 43.5 bits (101), Expect(2) = 2e-34,   Method: Compositional matrix adjust.
 Identities = 20/40 (50%), Positives = 29/40 (72%)
 Frame = +2

Query: 12 FKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATR 51
          FK+VL+G+S VGKS+L+ RF + +F+   +STIG  F  R
Sbjct: 32 FKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAF*LR 151
>34468
          Length = 1502

 Score =  129 bits (325), Expect = 6e-31,   Method: Compositional matrix adjust.
 Identities = 72/188 (38%), Positives = 115/188 (61%), Gaps = 5/188 (2%)
 Frame = +1

Query: 11  LFKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIQVDGKTIKAQIWDTAGQ 70
           +FK+++IGDS VGK+ L  RF   +F  ++++TIGV+F  +SIQVD + +K Q+WDTAGQ
Sbjct: 493 IFKIIVIGDSNVGKTCLTYRFCLGKFPDKTEATIGVDFREKSIQVDSEHLKLQLWDTAGQ 672

Query: 71  ERYR-AITSAYYRGAVGALLVYDIAKHLTYENVERWLKEL-RDHADSNIVIMLVGNKSDL 128
           ER+R ++   YYR     + VYD+ K  ++EN+  W++E  R +    I  +LVGNK D+
Sbjct: 673 ERFRKSMVQHYYRNVHAVVFVYDMTKMSSFENMPAWIEECDRHNLTKYIPRILVGNKCDV 852

Query: 129 RHLRAVPTDEARAFAEKNGLSFIETSALD---STNVEAAFQTILTEIYRIVSQKQMSDRR 185
               AV T+ A+ FA+ + +   ETSA D   + +V+A F T+    +++   K M    
Sbjct: 853 VERIAVNTNLAQKFADAHNMPLFETSAKDDEKANHVDAIFMTVA---HKLKXSKPMMPAH 1023

Query: 186 ENDMSPSN 193
            ++M P +
Sbjct: 1024LSEMVPGD 1047
>14456
          Length = 1867

 Score =  120 bits (301), Expect = 4e-28,   Method: Compositional matrix adjust.
 Identities = 69/180 (38%), Positives = 107/180 (59%), Gaps = 5/180 (2%)
 Frame = -1

Query: 21   GVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIQVDGKTIKAQIWDTAGQERYRAITSAY 80
            GVGKS+L++RF  N+F+ +S  TIGVEF  + + VD +T   QIWDTAGQER++++ + +
Sbjct: 1111 GVGKSSLMNRFVSNKFDAQSFHTIGVEFLNKDVVVDDETYTMQIWDTAGQERFKSLRTPF 932

Query: 81   YRGAVGALLVYDIAKHLTYENVERWLKELRDHAD----SNIVIMLVGNKSDLRHLRAVPT 136
            YRGA   LL + +    ++ N+  W KE   +AD         +++GNK D+   R V  
Sbjct: 931  YRGADCCLLTFSVDSMQSFRNLSMWRKEFLYYADIQDGVTFPFVVLGNKIDVEG-RQVTN 755

Query: 137  DEARAFAEKNG-LSFIETSALDSTNVEAAFQTILTEIYRIVSQKQMSDRRENDMSPSNNV 195
            +EAR++   N    + ETSA D+TNVE AF   L  + R+   +++ D++E   +  N V
Sbjct: 754  EEARSWCTANSNAPYFETSAKDATNVEKAF---LAAVQRL---REVEDQQEVKTAHGNTV 593
>26083
          Length = 432

 Score =  108 bits (270), Expect = 2e-24,   Method: Compositional matrix adjust.
 Identities = 44/114 (38%), Positives = 82/114 (71%)
 Frame = +1

Query: 12  FKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIQVDGKTIKAQIWDTAGQE 71
           FK+V +G+  VGK++L++RF  + F+   ++TIG++F ++++ ++ +TI+ Q+WDTAGQE
Sbjct: 79  FKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTIRLQLWDTAGQE 258

Query: 72  RYRAITSAYYRGAVGALLVYDIAKHLTYENVERWLKELRDHADSNIVIMLVGNK 125
           R+R++  +Y R +  A++VYDI    ++    +W+ ++R    S+++IMLVGNK
Sbjct: 259 RFRSLIPSYIRDSSVAVVVYDITNANSFHQTSKWIDDVRTERGSDVIIMLVGNK 420
>17511
          Length = 483

 Score =  107 bits (266), Expect = 5e-24,   Method: Compositional matrix adjust.
 Identities = 48/122 (39%), Positives = 81/122 (66%), Gaps = 4/122 (3%)
 Frame = -3

Query: 11  LFKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIQVDGKTIKAQIWDTAGQ 70
           L KV+++GDSGVGK++L++++   +F+ + K+TIG +F T+ + VD + +  QIWDTAGQ
Sbjct: 367 LLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQIWDTAGQ 188

Query: 71  ERYRAITSAYYRGAVGALLVYDIAKHLTYENVERWLKELRDHADS----NIVIMLVGNKS 126
           ER++++  A+YRGA   +LV+D+    T+ +++ W  E    A      N   +++GNK 
Sbjct: 187 ERFQSLGVAFYRGADCCVLVFDVTMPNTFRSLDSWRDEFLIQASPRDPENFPFVVIGNKI 8

Query: 127 DL 128
           DL
Sbjct: 7   DL 2
>05468
          Length = 1558

 Score =  104 bits (259), Expect = 3e-23,   Method: Compositional matrix adjust.
 Identities = 63/212 (29%), Positives = 115/212 (54%), Gaps = 7/212 (3%)
 Frame = -3

Query: 9    DYLFKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIQVDGKT-IKAQIWDT 67
            ++L+K+++IG+ G GK++++ R+    F+   ++TIGV+FA + +  D  T I+ Q+WD 
Sbjct: 1547 EHLYKILVIGELGTGKTSIIKRYVHQFFSQHYRATIGVDFALKVLNWDADTLIRLQLWDI 1368

Query: 68   AGQERYRAITSAYYRGAVGALLVYDIAKHLTYENVERWLKELRDHAD----SNIVIMLVG 123
            AGQER+  +T  YY+ AVGA +V+D+ +  T++ V +W  +L         S +  +L+ 
Sbjct: 1367 AGQERFGNMTRVYYKEAVGAFVVFDVTRASTFDAVTKWKNDLDSKVQLADGSPVPCVLLA 1188

Query: 124  NKSDLRHLRAV-PTDEARAF-AEKNGLSFIETSALDSTNVEAAFQTILTEIYRIVSQKQM 181
            NK D      V  T +   F +EK  + + ETSA ++ N++ A + ++T I       Q+
Sbjct: 1187 NKCDQAKEGLVNNTSQMDEFCSEKGFIGWYETSAKENINIDEAARFLVTRILEKDRAMQL 1008

Query: 182  SDRRENDMSPSNNVVPIHVPPTTENKPKVQCC 213
                  D     + + +  P +   + K+ CC
Sbjct: 1007 G-----DDDRDRDRIVLDKPSSGTQERKINCC 927
>33794
          Length = 779

 Score =  103 bits (256), Expect = 7e-23,   Method: Compositional matrix adjust.
 Identities = 57/176 (32%), Positives = 97/176 (55%), Gaps = 12/176 (6%)
 Frame = -1

Query: 46  VEFATRSIQVDGKTIKAQIWDTAGQERYRAITSAYYRGAVGALLVYDIAKHLTYENVERW 105
           V + T +I ++GK +K QIWDT+GQ R+  I  +Y RGA G +LVYDI    +++ ++RW
Sbjct: 692 VAYKTTTILLEGKRVKLQIWDTSGQGRFCTIIRSYSRGAQGIILVYDITNKWSFDGIDRW 513

Query: 106 LKELRDHADSNIVIMLVGNKSDLRHLRAVPTDEARAFAEKNGLSFIETSALDSTNVEAAF 165
           LKE+ +HA   I  +LVGN+  L + R V   +A  +A +N +S  E S L   N+  +F
Sbjct: 512 LKEVEEHAP-GIPKVLVGNRLHLAYKRQVAAKQAETYASRNNMSCFEISPLCDFNIRESF 336

Query: 166 QTI---------LTEIYR---IVSQKQMSDRRENDMSPSNNVVPIHVPPTTENKPK 209
             +         +  I+R   ++S +++  R     +    +  +H+PP+ ++  K
Sbjct: 335 CELARMALHRNGMEHIWRSNKVLSLQELCCRTIVRRTSVYAIDSLHLPPSVKSTLK 168
>01398
          Length = 1421

 Score =  101 bits (251), Expect = 2e-22,   Method: Compositional matrix adjust.
 Identities = 54/145 (37%), Positives = 76/145 (52%), Gaps = 1/145 (0%)
 Frame = -2

Query: 70   QERYRAITSAYYRGAVGALLVYDIAKHLTYENVERWLKELRDHADSNIVIMLV-GNKSDL 128
            QER+R+IT +YYR +VG ++VYDI K  T+EN+++W +E R+H + +  I LV G+KSD 
Sbjct: 1420 QERFRSITRSYYRNSVGVIIVYDITKRSTFENLKQWYEEARNHIEPHKAIFLVLGHKSDR 1241

Query: 129  RHLRAVPTDEARAFAEKNGLSFIETSALDSTNVEAAFQTILTEIYRIVSQKQMSDRREND 188
               R V   E R FAE +GL F ETSA    N+E  F  I  + Y+ +    +      D
Sbjct: 1240 EDARQVTAREGRRFAEMHGLKFFETSAKSGHNIEDVFAQIAKDTYQHLQDGHIRLEEGWD 1061

Query: 189  MSPSNNVVPIHVPPTTENKPKVQCC 213
                    P       E +    CC
Sbjct: 1060 GVKQGFARPRETVHLAEGEESGGCC 986
>07465
          Length = 1103

 Score = 98.6 bits (244), Expect = 1e-21,   Method: Compositional matrix adjust.
 Identities = 52/144 (36%), Positives = 83/144 (57%)
 Frame = +3

Query: 25  SNLLSRFTRNEFNLESKSTIGVEFATRSIQVDGKTIKAQIWDTAGQERYRAITSAYYRGA 84
           S+++ R+ +  F  + K TIGV+F  R I+V G+ ++  +WDTAGQE + AIT AYYRGA
Sbjct: 240 SSMIQRYCKGIFTKDYKKTIGVDFLERQIEVGGEDVRLMLWDTAGQEEFDAITKAYYRGA 419

Query: 85  VGALLVYDIAKHLTYENVERWLKELRDHADSNIVIMLVGNKSDLRHLRAVPTDEARAFAE 144
              +L +      ++E +E W +++ D     I +++V NK DL     V  +EA   A+
Sbjct: 420 QACVLAFSTVDRDSFEALETWKRKVEDEV-GEIGMVIVQNKIDLIDDAVVRPEEAENLAK 596

Query: 145 KNGLSFIETSALDSTNVEAAFQTI 168
           K  L F  TS  ++ NV+  F+ +
Sbjct: 597 KLRLRFYRTSVKENMNVDEVFRYL 668
>32723
          Length = 384

 Score = 92.8 bits (229), Expect = 9e-20,   Method: Compositional matrix adjust.
 Identities = 45/111 (40%), Positives = 70/111 (63%)
 Frame = +2

Query: 70  QERYRAITSAYYRGAVGALLVYDIAKHLTYENVERWLKELRDHADSNIVIMLVGNKSDLR 129
           QER+R+IT +YYR A   +LVYD+    +YE++ +W+ E+  +A + ++  LVGNK D  
Sbjct: 2   QERFRSITQSYYRSANALILVYDVCSQQSYESLPQWIHEIELYAGTKVLAFLVGNKIDQT 181

Query: 130 HLRAVPTDEARAFAEKNGLSFIETSALDSTNVEAAFQTILTEIYRIVSQKQ 180
             R +PT   + FAE+  + F+ETSA ++ NVE  F TI    Y++ +Q Q
Sbjct: 182 DKREIPTHIGKEFAERYEMRFLETSAKEADNVEKLFSTI---AYQLTAQAQ 325
>13901
          Length = 962

 Score = 90.9 bits (224), Expect = 4e-19,   Method: Compositional matrix adjust.
 Identities = 41/96 (42%), Positives = 64/96 (66%), Gaps = 1/96 (1%)
 Frame = -3

Query: 11  LFKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIQVDGKT-IKAQIWDTAG 69
           LFKV++IGD  VGK++ + R+  + F  + K TIGV+FA + I+   K  IK Q+WD AG
Sbjct: 288 LFKVIIIGDPTVGKTSFVQRYVNDSFRRDYKMTIGVDFALKVIRWSDKCNIKLQLWDIAG 109

Query: 70  QERYRAITSAYYRGAVGALLVYDIAKHLTYENVERW 105
           QER+ ++T  YY+ A   ++++D+ +  TY+N  RW
Sbjct: 108 QERFTSMTRVYYKDAHACIVMFDLTQKNTYQNAIRW 1
>11257
          Length = 1102

 Score = 87.0 bits (214), Expect = 4e-18,   Method: Compositional matrix adjust.
 Identities = 46/139 (33%), Positives = 82/139 (58%), Gaps = 5/139 (3%)
 Frame = -2

Query: 51   RSIQVDGKTIKAQIWDTAGQERYRAITSAYYRGAVGALLVYDIAKHLTYENVERWLKELR 110
            + + VDG+T   QIWDTAGQERY+++ + +YRG    LL + +    + +++  W  E  
Sbjct: 1053 KDVVVDGETFTMQIWDTAGQERYKSLRTPFYRGTDCCLLTFSVDNLKSLQSLSDWYDEFV 874

Query: 111  DHAD----SNIVIMLVGNKSDLRHLRAVPTDEARAFAEKNG-LSFIETSALDSTNVEAAF 165
            ++AD    ++   +++GNK+D+   R V +++A  +   +G L + ETSA DS NV+ AF
Sbjct: 873  NYADIQDSASFPFVIIGNKADIEE-REVSSEDAYNWCRTHGNLPYFETSAKDSLNVQQAF 697

Query: 166  QTILTEIYRIVSQKQMSDR 184
              ++  +  +   +QM +R
Sbjct: 696  LAVVRRLREM--DEQMDER 646
>33380
          Length = 282

 Score = 85.5 bits (210), Expect = 2e-17,   Method: Compositional matrix adjust.
 Identities = 37/75 (49%), Positives = 53/75 (70%)
 Frame = +3

Query: 58  KTIKAQIWDTAGQERYRAITSAYYRGAVGALLVYDIAKHLTYENVERWLKELRDHADSNI 117
           K +K QIWDTAGQERYR IT+AYYRGA+G +L+YD+    ++  V+ W  +++ ++  N 
Sbjct: 54  KRVKLQIWDTAGQERYRTITTAYYRGAMGFILMYDVTNEESFNAVQDWCTQIKTYSWDNA 233

Query: 118 VIMLVGNKSDLRHLR 132
            ++LVGNK DL   R
Sbjct: 234 QVVLVGNKCDLEDER 278
>01972
          Length = 2359

 Score = 71.2 bits (173), Expect(2) = 3e-17,   Method: Compositional matrix adjust.
 Identities = 39/124 (31%), Positives = 64/124 (51%)
 Frame = +3

Query: 42  STIGVEFATRSIQVDGKTIKAQIWDTAGQERYRAITSAYYRGAVGALLVYDIAKHLTYEN 101
           +T+GVE            +K  +WDTAGQE++  +   YY     A++++D+   +TY+N
Sbjct: 393 ATLGVEVHPLLFHTSRGKLKFNVWDTAGQEKFGGLRDGYYIQGQCAVIMFDVTSRVTYKN 572

Query: 102 VERWLKELRDHADSNIVIMLVGNKSDLRHLRAVPTDEARAFAEKNGLSFIETSALDSTNV 161
           V  W ++L    + NI I+L GNK D++  +     +A  F  K  L + + SA  + N 
Sbjct: 573 VPNWHRDLVRVCE-NIPIVLCGNKVDIKDRKV--KAKAIVFHRKKNLQYYDISAKSNYNF 743

Query: 162 EAAF 165
           E  F
Sbjct: 744 EKPF 755

 Score = 33.9 bits (76), Expect(2) = 3e-17,   Method: Compositional matrix adjust.
 Identities = 14/30 (46%), Positives = 19/30 (63%)
 Frame = +1

Query: 7   EYDYLFKVVLIGDSGVGKSNLLSRFTRNEF 36
           E +  FK+VL+GD GVGK+  + R    EF
Sbjct: 289 EQEPTFKLVLVGDGGVGKTTFVKRHVTGEF 378
>13750
          Length = 503

 Score = 83.2 bits (204), Expect = 7e-17,   Method: Compositional matrix adjust.
 Identities = 58/170 (34%), Positives = 88/170 (51%), Gaps = 4/170 (2%)
 Frame = -2

Query: 24  KSNLLSRFTRNEFNLESKSTIGV---EFATRSIQVDGKTIKAQIWDTAGQERYRAITSAY 80
           K+ LL R+ +  F   +  TI V   EF     + D   ++  +WDT G E YR++  ++
Sbjct: 502 KTCLLRRYQKGFFMDRTMPTIAVLCSEF--NESRTDPLNVRYTLWDTGGAETYRSLWVSH 329

Query: 81  YRGAVGALLVYDIAKHLTYENVER-WLKELRDHADSNIVIMLVGNKSDLRHLRAVPTDEA 139
           +RGA  ALLVYD+    ++      W K L  +     VI  VG+K+DL   R + T+  
Sbjct: 328 FRGAQVALLVYDVTCEWSFLTATTVWRKALMKNIPEAQVI-FVGSKTDLEENRVISTERG 152

Query: 140 RAFAEKNGLSFIETSALDSTNVEAAFQTILTEIYRIVSQKQMSDRRENDM 189
           +AFA + G +F ETS++   NV+A F     EI  I+++ Q S   E  M
Sbjct: 151 QAFATQCGYTFFETSSVTGKNVDAVFW----EIAFILARLQRSAHLELSM 14
>19006
          Length = 568

 Score = 77.8 bits (190), Expect = 3e-15,   Method: Compositional matrix adjust.
 Identities = 43/119 (36%), Positives = 67/119 (56%), Gaps = 1/119 (0%)
 Frame = -2

Query: 13  KVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIQVDGKTIKAQIWDTAGQER 72
           K+V++GD   GK+ LL  F++++F      T+   +    I+VD K ++  +WDTAGQE 
Sbjct: 432 KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVA-DIEVDSKQVELALWDTAGQED 256

Query: 73  YRAITSAYYRGAVGALLVYDIAKHLTYENV-ERWLKELRDHADSNIVIMLVGNKSDLRH 130
           Y  +    Y      L+ + I    + EN+ E+W  E+R H   N+ I+LVGNK DLR+
Sbjct: 255 YDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVR-HFCPNVPIILVGNKKDLRN 82
>30760
          Length = 596

 Score = 76.6 bits (187), Expect = 6e-15,   Method: Compositional matrix adjust.
 Identities = 50/175 (28%), Positives = 87/175 (49%), Gaps = 6/175 (3%)
 Frame = -1

Query: 13  KVVLIGDSGVGKSNLLSRFTRN--EFNLESKSTIGVEFATRSIQVDGK--TIKAQIWDTA 68
           K ++ GDSGVGKS++   F  +   F      T GVE   + + +      ++  ++D+A
Sbjct: 524 KCIVTGDSGVGKSSICQVFHSDSAHFPKNYSMTTGVEVLVKLVNIPDSRDQVELYLFDSA 345

Query: 69  GQERYRAITSAYYRGAVGALLVYDIAKHLTYENVERWLKELRDHADSNIVI--MLVGNKS 126
           G+E +    + ++      ++VYD+    ++    RWL+ +R  A  N VI  +LV NK+
Sbjct: 344 GKEIFSENVTKFWDQPSVVMVVYDVTDETSFSGCVRWLERVR-AAKPNTVIPGVLVANKT 168

Query: 127 DLRHLRAVPTDEARAFAEKNGLSFIETSALDSTNVEAAFQTILTEIYRIVSQKQM 181
           DL   R V   E +  A+ +GL + E SA +  N +  F   L   +  + Q+Q+
Sbjct: 167 DLDERRRVSRKEGKDLAQSHGLEYFECSAKEMQNTDTPF-FCLAHAFHKLYQEQL 6
>01095
          Length = 1745

 Score = 73.9 bits (180), Expect = 5e-14,   Method: Compositional matrix adjust.
 Identities = 38/84 (45%), Positives = 53/84 (63%)
 Frame = -1

Query: 89   LVYDIAKHLTYENVERWLKELRDHADSNIVIMLVGNKSDLRHLRAVPTDEARAFAEKNGL 148
            +VYDI    T+   + W+KEL+  A  NIVI L GNK+DL + R V  +EA+A+AE+N L
Sbjct: 1745 VVYDITNQDTFGRAKTWVKELQRQASPNIVIALAGNKADLANKRMVEFEEAQAYAEENSL 1566

Query: 149  SFIETSALDSTNVEAAFQTILTEI 172
             F+ETSA  + NV   F  I  ++
Sbjct: 1565 LFMETSAKTAMNVNDIFLAIAKKL 1494
>11728
          Length = 635

 Score = 73.6 bits (179), Expect = 5e-14,   Method: Compositional matrix adjust.
 Identities = 43/118 (36%), Positives = 63/118 (53%), Gaps = 1/118 (0%)
 Frame = -1

Query: 13  KVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIQVDGKTIKAQIWDTAGQER 72
           K V++GD  VGK+ LL  +T N F  E   T+   ++  ++ VD K I   +WDTAGQE 
Sbjct: 485 KCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSA-NVMVDSKPINLGLWDTAGQED 309

Query: 73  YRAITSAYYRGAVGALLVYDIAKHLTYENVE-RWLKELRDHADSNIVIMLVGNKSDLR 129
           Y  +    Y      L+ + +    ++ENV+ +W  E+  H   N  I+LVG K DLR
Sbjct: 308 YDRLRPLSYPQTDVFLICFSLISPASFENVKAKWYPEVSHHC-PNTPIILVGTKLDLR 138
>07580
          Length = 921

 Score = 73.6 bits (179), Expect = 5e-14,   Method: Compositional matrix adjust.
 Identities = 39/123 (31%), Positives = 65/123 (52%), Gaps = 1/123 (0%)
 Frame = +3

Query: 51  RSIQVDGKTIKAQIWDTAGQERYRAITSAYYRGAVGALLVYDIAKHLTYENVERWLKE-L 109
           + ++VDG+    +I DTAG E++ A+   Y +   G LL Y I    T+ +++   ++ L
Sbjct: 177 KQVEVDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFLLAYSITAQSTFNDLQELREQIL 356

Query: 110 RDHADSNIVIMLVGNKSDLRHLRAVPTDEARAFAEKNGLSFIETSALDSTNVEAAFQTIL 169
           R     ++ ++LVGNK DL   R V  D+ +  A     +F+ETSA    NV   F  ++
Sbjct: 357 RVKDTDDVPMLLVGNKCDLEDERVVGKDQGQGLARSFSCAFLETSAKARINVNEIFMDLV 536

Query: 170 TEI 172
            +I
Sbjct: 537 RQI 545
>35581
          Length = 364

 Score = 73.6 bits (179), Expect = 6e-14,   Method: Compositional matrix adjust.
 Identities = 40/87 (45%), Positives = 53/87 (60%), Gaps = 2/87 (2%)
 Frame = +2

Query: 12  FKVVLIGDSGVGKSNLLSRFTRNEFNLES--KSTIGVEFATRSIQVDGKTIKAQIWDTAG 69
           FK VL+GD+GVGK+ LL+R   ++F L+S   S       T      G      +WDTAG
Sbjct: 47  FKCVLLGDAGVGKTCLLNRLATDKF-LDSPLTSLTTASLLTTVTLTSGVMASVDLWDTAG 223

Query: 70  QERYRAITSAYYRGAVGALLVYDIAKH 96
           QERYR++TS+YYR     L+VYD A+H
Sbjct: 224 QERYRSLTSSYYRDTKAVLIVYD-AEH 301
>12339
          Length = 578

 Score = 70.5 bits (171), Expect = 5e-13,   Method: Compositional matrix adjust.
 Identities = 36/104 (34%), Positives = 63/104 (60%), Gaps = 5/104 (4%)
 Frame = -2

Query: 70  QERYRAITSAYYRGAVGALLVYDIAKHLTYENVERWLKELRDHAD----SNIVIMLVGNK 125
           QER++++  A+YRGA   +LVYD+ +  T+++++ W +E  + A      +   +++GNK
Sbjct: 577 QERFQSLGVAFYRGADCCILVYDVTEXKTFDSLDSWQREFLNQASPRDPEHFPFVVIGNK 398

Query: 126 SDLRHLRAVPTDEARAFAE-KNGLSFIETSALDSTNVEAAFQTI 168
            DL + R V     + +   K G+ + ETSA ++ NVE AFQT+
Sbjct: 397 IDLDN-RVVTAKRGQGWCSTKGGIPYFETSAKEAINVEQAFQTV 269
>26536
          Length = 829

 Score = 68.9 bits (167), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 39/112 (34%), Positives = 60/112 (53%), Gaps = 3/112 (2%)
 Frame = +2

Query: 66  DTAGQERYRAITSAYYRGAVGALLVYDIAKHLTYENVE---RWLKELRDHADSNIVIMLV 122
           DTAGQE Y ++   Y R   G ++VY +    +++  E   RWL   +D  +++I  +L 
Sbjct: 146 DTAGQEEYSSMREHYTRSGDGFIVVYSVTDVTSFQEAEAVFRWLTRFQD--ETSIHAVLC 319

Query: 123 GNKSDLRHLRAVPTDEARAFAEKNGLSFIETSALDSTNVEAAFQTILTEIYR 174
           GNK+DL   R V  +E R  A++ G+ + ETSA    NV   +  +L  I R
Sbjct: 320 GNKTDLTSDRKVTPEEGRKMADRLGMLYFETSAKTGDNVSQVYHGLLRSIPR 475

 Score = 34.3 bits (77), Expect = 0.044,   Method: Compositional matrix adjust.
 Identities = 13/25 (52%), Positives = 20/25 (80%)
 Frame = +2

Query: 12  FKVVLIGDSGVGKSNLLSRFTRNEF 36
           +K+V++G  GVGKS+L  RFT++ F
Sbjct: 488 YKIVMLGSGGVGKSSLTIRFTQDTF 562
>34359
          Length = 1042

 Score = 68.9 bits (167), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 36/118 (30%), Positives = 63/118 (53%)
 Frame = +3

Query: 12  FKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIQVDGKTIKAQIWDTAGQE 71
           FK+VL+G      +N++ R        +  +T+GVE            ++  +WDTAGQE
Sbjct: 54  FKLVLVGGRWEWANNIVKRHVTGS*K-KYVATLGVEVHPLQFNTSRGLLRFNVWDTAGQE 230

Query: 72  RYRAITSAYYRGAVGALLVYDIAKHLTYENVERWLKELRDHADSNIVIMLVGNKSDLR 129
           ++  +   YY     A++++D+   +TY+NV  W ++L    + NI I+L GNK D++
Sbjct: 231 KFGGLRDGYYIQGTCAIIMFDVTSRVTYKNVPNWHRDLVRVCE-NIPIVLCGNKVDIK 401
>13745
          Length = 1045

 Score = 67.8 bits (164), Expect = 3e-12,   Method: Compositional matrix adjust.
 Identities = 39/104 (37%), Positives = 62/104 (59%), Gaps = 5/104 (4%)
 Frame = +2

Query: 70  QERYRAITSAYYRGAVGALLVYDIAKHLTYENVERWLKELRDHADS----NIVIMLVGNK 125
           QER++++  A+YRGA   +LVYD+    +++N++ W  E    A      +   +++GNK
Sbjct: 2   QERFQSLGVAFYRGADCCVLVYDVTAPNSFKNLDSWRDEFLIQASPRDPEHFPFVVLGNK 181

Query: 126 SDLRHLRAVPTDEARAFAE-KNGLSFIETSALDSTNVEAAFQTI 168
            DL + R V T  A+ + + KN + + ETSA +  NVE AFQTI
Sbjct: 182 VDLDN-RQVSTRRAQQWCQSKNDIPYYETSAKEGINVEMAFQTI 310
>19656
          Length = 428

 Score = 65.9 bits (159), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 34/102 (33%), Positives = 54/102 (52%), Gaps = 1/102 (0%)
 Frame = +3

Query: 13  KVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIQVDGKTIKAQIWDTAGQER 72
           K V++GD  VGK+ LL  +T N F  E   T+   ++  ++ VDG+ +   +WDTAGQE 
Sbjct: 117 KCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSA-NVMVDGRPVNLGLWDTAGQED 293

Query: 73  YRAITSAYYRGAVGALLVYDIAKHLTYENVE-RWLKELRDHA 113
           Y  +    Y      LL + +A   ++EN+  +W  E+  H 
Sbjct: 294 YDRLRPLSYPQTDVFLLCFSVASPASFENIRAKWYPEVNHHC 419
>00858
          Length = 1658

 Score = 65.9 bits (159), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 46/150 (30%), Positives = 78/150 (52%), Gaps = 1/150 (0%)
 Frame = -2

Query: 24   KSNLLSRFTRNEFNLESKSTIGVEFATRSIQVDGKTIKAQIWDTAGQERYRAITSAYYRG 83
            KS L  +  +N F +E       +   + + +DG+T    I DTAGQE   A+     R 
Sbjct: 1552 KSALTIQLXQNHF-VEEYDPTXEDSXRKQVVIDGETCLLDILDTAGQEEXSAMRDQCMRT 1376

Query: 84   AVGALLVYDIAKHLTYENVERWLKELRDHADSNIVIM-LVGNKSDLRHLRAVPTDEARAF 142
              G L V+ +    ++E++ ++ ++++   D++ V M LVGNK DL  +R V   + +  
Sbjct: 1375 GEGFLCVFAVXNLKSFEDINQYREQIKRVKDADEVPMVLVGNKVDL-PIRNVEQRQGKHM 1199

Query: 143  AEKNGLSFIETSALDSTNVEAAFQTILTEI 172
            AE   + ++ETSA     V+ AF T++ EI
Sbjct: 1198 AELYHIPYVETSAKTRQGVDDAFYTLVREI 1109
>09204
          Length = 1051

 Score = 65.5 bits (158), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 35/101 (34%), Positives = 53/101 (52%), Gaps = 4/101 (3%)
 Frame = -3

Query: 72   RYRAITSAYYRGAVGALLVYDIAKHLTYENVERWLKELRDHADSNIVIMLVGNKSDLRH- 130
            RY A++  YYRGA  A+L +D+    +++ +  W+ ELR H +    + + G K DL H 
Sbjct: 1049 RYEAMSRIYYRGAKAAILCFDLTDKSSFDRIRFWIGELRQH-EEECKLYICGTKFDLVHD 873

Query: 131  ---LRAVPTDEARAFAEKNGLSFIETSALDSTNVEAAFQTI 168
                RAVP   A+A A+       ETS++   N+E  F  I
Sbjct: 872  DPERRAVPRSVAKALADDCMAEIYETSSMTGDNIEKLFTKI 750
>00552
          Length = 455

 Score = 64.7 bits (156), Expect = 3e-11,   Method: Compositional matrix adjust.
 Identities = 30/53 (56%), Positives = 40/53 (75%)
 Frame = -1

Query: 11  LFKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIQVDGKTIKAQ 63
           L KVVL+GD GVGKS+L++RF  N+F+ +S  TIGVEF T+ + VDG+T   Q
Sbjct: 446 LLKVVLLGDGGVGKSSLMNRFVSNKFDAQSFHTIGVEFLTKDVVVDGETFTMQ 288

 Score = 44.3 bits (103), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 17/49 (34%), Positives = 30/49 (61%)
 Frame = -3

Query: 64  IWDTAGQERYRAITSAYYRGAVGALLVYDIAKHLTYENVERWLKELRDH 112
           IWDTAGQERY+++ + +YRG    LL + +    + +++  W  E  ++
Sbjct: 147 IWDTAGQERYKSLRTPFYRGTDCCLLTFSVDNLKSLQSLSDWYDEFVNY 1
>27191
          Length = 443

 Score = 63.2 bits (152), Expect = 8e-11,   Method: Compositional matrix adjust.
 Identities = 26/102 (25%), Positives = 58/102 (56%)
 Frame = +1

Query: 24  KSNLLSRFTRNEFNLESKSTIGVEFATRSIQVDGKTIKAQIWDTAGQERYRAITSAYYRG 83
           K+ L+  F  ++FN   + T+GV++  +   V+G  ++  +WD +G   Y  + +  Y G
Sbjct: 1   KTCLIKHFCESKFNQGYQPTVGVDYGFKIQTVNGVDMRVHMWDLSGSNEYLDVRNELYTG 180

Query: 84  AVGALLVYDIAKHLTYENVERWLKELRDHADSNIVIMLVGNK 125
           +    +V+D++   ++E ++ WL+E+   A  + + ++VGN+
Sbjct: 181 SDAIFIVFDVSNTPSFEALDSWLREINRFATGSPLNVIVGNR 306
>14119
          Length = 602

 Score = 61.6 bits (148), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 34/78 (43%), Positives = 44/78 (56%), Gaps = 1/78 (1%)
 Frame = +1

Query: 98  TYENVERWLKELRDHADSNIVIMLVGNKSDL-RHLRAVPTDEARAFAEKNGLSFIETSAL 156
           T+     W+KELR     +++I+L GNK+DL    RAV  D+AR FAE NGL F E SA 
Sbjct: 1   TFNRALAWVKELRQQNAGSVLIVLAGNKADLASEHRAVSADDARTFAEDNGLIFAEVSAK 180

Query: 157 DSTNVEAAFQTILTEIYR 174
               V   F TI  ++ R
Sbjct: 181 TGMAVSEVFMTIAHKLVR 234
>29380
          Length = 853

 Score = 61.2 bits (147), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 35/93 (37%), Positives = 54/93 (58%), Gaps = 2/93 (2%)
 Frame = -2

Query: 84  AVGALLVYDIAKHLTYENVERWLKELRDHADSNIVIMLVGNKSDL--RHLRAVPTDEARA 141
           A  A++VYD+    T+     W+KELR     +++I+L GNK DL  +H RAV  ++A++
Sbjct: 852 ASAAIIVYDVNIADTFSRALAWVKELRQQNTESVLIILAGNKVDLATQH-RAVSFEDAQS 676

Query: 142 FAEKNGLSFIETSALDSTNVEAAFQTILTEIYR 174
           FA +NGL F E SA     V   F T+  ++ +
Sbjct: 675 FARENGLLFAEVSAKTGMAVNEIFMTLANQLIQ 577
>34597
          Length = 773

 Score = 58.5 bits (140), Expect(2) = 3e-10,   Method: Compositional matrix adjust.
 Identities = 30/105 (28%), Positives = 57/105 (54%), Gaps = 8/105 (7%)
 Frame = -2

Query: 98  TYENVERWLKELRDHADSNIVIMLVGNKSDLRHLRAVPTDEARAFAEKNGLSFIETSALD 157
           ++EN+ +WL+ + +HA+ ++  M++GNK D+   R V  +   A A ++ + F+ETSA  
Sbjct: 709 SFENIVKWLRNIDEHANEDVEKMILGNKCDMTDKRVVSKERGEAIAREHSIRFMETSAKS 530

Query: 158 STNVEAAFQTILTEIYRIVSQKQMS--------DRRENDMSPSNN 194
           + N+E AF  +   I    + ++ +        DR  +D +P  N
Sbjct: 529 NINIERAFCELAEAILDKTAGRESAENPERVVIDRGNSDKAPGYN 395

 Score = 22.3 bits (46), Expect(2) = 3e-10,   Method: Compositional matrix adjust.
 Identities = 8/13 (61%), Positives = 12/13 (92%)
 Frame = -3

Query: 78  SAYYRGAVGALLV 90
           ++YYRGA+G +LV
Sbjct: 771 TSYYRGAMGIMLV 733
>25618
          Length = 475

 Score = 57.8 bits (138), Expect = 4e-09,   Method: Compositional matrix adjust.
 Identities = 34/77 (44%), Positives = 43/77 (55%), Gaps = 1/77 (1%)
 Frame = +3

Query: 107 KELRDHADSNIVIMLVGNKSDL-RHLRAVPTDEARAFAEKNGLSFIETSALDSTNVEAAF 165
           KELR     +++I+L GNK+DL    RAV  D+AR FAE NGL F E SA     V   F
Sbjct: 48  KELRQQNAGSVLIVLAGNKADLASEHRAVSADDARTFAEDNGLIFAEVSAKTGMAVSEVF 227

Query: 166 QTILTEIYRIVSQKQMS 182
            TI  ++ R   + Q S
Sbjct: 228 MTIAHKLVRRAEEGQGS 278
>10708
          Length = 2775

 Score = 44.7 bits (104), Expect(2) = 3e-08,   Method: Compositional matrix adjust.
 Identities = 29/80 (36%), Positives = 43/80 (53%), Gaps = 13/80 (16%)
 Frame = -3

Query: 101  NVERWLKELRDHADSNIVIMLVGNKSDLRH----------LRAVPT--DEARAFAEK-NG 147
            ++++W  E+R H   N+ I+LVGNK DLR+          ++  P   DE RA +EK N 
Sbjct: 2596 SLKKWTPEVR-HFCPNVPIILVGNKKDLRNDENTKRELMKMKQEPVRLDEGRAMSEKINA 2420

Query: 148  LSFIETSALDSTNVEAAFQT 167
             S++E SA     V   F+T
Sbjct: 2419 YSYLECSAKTKEGVREVFET 2360

 Score = 29.6 bits (65), Expect(2) = 3e-08,   Method: Compositional matrix adjust.
 Identities = 13/45 (28%), Positives = 22/45 (48%)
 Frame = -2

Query: 58   KTIKAQIWDTAGQERYRAITSAYYRGAVGALLVYDIAKHLTYENV 102
            + ++  +WDTAGQE Y  +    Y      L+ + I    + EN+
Sbjct: 2729 QQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENI 2595
>14775
          Length = 380

 Score = 54.3 bits (129), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 47/169 (27%), Positives = 70/169 (41%), Gaps = 3/169 (1%)
 Frame = -2

Query: 24  KSNLLSRFTRNEFNLESKSTIGV---EFATRSIQVDGKTIKAQIWDTAGQERYRAITSAY 80
           K+ LL R+ +  F   +  TI V   EF     + D   ++  +WDT G E YR++  ++
Sbjct: 379 KTCLLRRYQKGFFMDRTMPTIAVLCSEF--NESRTDPLNVRYTLWDTGGAETYRSLWVSH 206

Query: 81  YRGAVGALLVYDIAKHLTYENVERWLKELRDHADSNIVIMLVGNKSDLRHLRAVPTDEAR 140
           +RGA  ALLVYD                                         V  +  +
Sbjct: 205 FRGAQVALLVYD-----------------------------------------VTCERGQ 149

Query: 141 AFAEKNGLSFIETSALDSTNVEAAFQTILTEIYRIVSQKQMSDRRENDM 189
           AFA + G +F ETS++   NV+A F     EI  I+++ Q S   E  M
Sbjct: 148 AFATQCGYTFFETSSVTGKNVDAVFW----EIAFILARLQRSAHLELSM 14
>24619
          Length = 509

 Score = 53.1 bits (126), Expect = 8e-08,   Method: Compositional matrix adjust.
 Identities = 34/105 (32%), Positives = 54/105 (51%), Gaps = 2/105 (1%)
 Frame = -2

Query: 70  QERYRAITSAYYRGAVGALLVYDIAKHLTYENVERWLKELRDHADSNIVIM-LVGNKSDL 128
           QE + A+   Y R   G LLV+ +  + ++EN+  +  ++    D +   M L  NK DL
Sbjct: 508 QEEFSAMREQYMRKGDGFLLVFSVIDYQSFENMVNFHTQILRVKDRDTYPMILCANKVDL 329

Query: 129 RHLRAVPTDEARAFAEKNGLSFIETSALDST-NVEAAFQTILTEI 172
            H R V  ++ R  A +  + +IETSA D   NV+ AF  ++  I
Sbjct: 328 VHQRKVSEEQVRDLATRLRIPYIETSAKDPPLNVDLAFHQVVRVI 194
>19046
          Length = 445

 Score = 53.1 bits (126), Expect = 9e-08,   Method: Compositional matrix adjust.
 Identities = 34/105 (32%), Positives = 54/105 (51%), Gaps = 2/105 (1%)
 Frame = -2

Query: 70  QERYRAITSAYYRGAVGALLVYDIAKHLTYENVERWLKE-LRDHADSNIVIMLVGNKSDL 128
           QE + A+   Y R   G LLV+ +    ++EN+  +  + LR     +  ++L  NK DL
Sbjct: 444 QEEFSAMREQYMRKGDGFLLVFSVTDFRSFENMANFHTQILRVKDRDSYPMILCANKVDL 265

Query: 129 RHLRAVPTDEARAFAEKNGLSFIETSALDST-NVEAAFQTILTEI 172
            H R V  ++ R  A +  + +IETSA D   NV+ AF  ++  I
Sbjct: 264 VHQRKVSEEQVRDLATRLRIPYIETSAKDPPLNVDLAFHQVVRVI 130
>31291
          Length = 446

 Score = 50.1 bits (118), Expect = 7e-07,   Method: Compositional matrix adjust.
 Identities = 26/69 (37%), Positives = 39/69 (56%), Gaps = 1/69 (1%)
 Frame = -1

Query: 63  QIWDTAGQERYRAITSAYYRGAVGALLVYDIAKHLTYENVE-RWLKELRDHADSNIVIML 121
           Q+WDTAGQE Y  +    Y      +L + +    + +NV+ +W  E+R H D ++ I+L
Sbjct: 443 QLWDTAGQEDYDRLRPLAYPNTDVFMLXFSLMSEASMKNVKVKWYPEIRHH-DPHVPIVL 267

Query: 122 VGNKSDLRH 130
           VG K DLR 
Sbjct: 266 VGTKLDLRQ 240
>09827
          Length = 1201

 Score = 46.2 bits (108), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 38/137 (27%), Positives = 63/137 (45%), Gaps = 1/137 (0%)
 Frame = -3

Query: 13   KVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIQVDGKTIKAQIWDTAGQER 72
            +++++G    GK+ +L +    E  + +  TIG    T    V+ K I   +WD  GQ++
Sbjct: 1109 RILMVGLDAAGKTTILYKLKLGEI-VTTIPTIGFNVET----VEYKNISFTVWDVGGQDK 945

Query: 73   YRAITSAYYRGAVGALLVYDIA-KHLTYENVERWLKELRDHADSNIVIMLVGNKSDLRHL 131
             R +   Y++   G + V D   K    E  E   + L +    + V+++  NK DL H 
Sbjct: 944  IRPLWRHYFQNTQGLIFVVDSNDKERVQEAREELTRMLNEDELRDAVLLVFANKQDLPH- 768

Query: 132  RAVPTDEARAFAEKNGL 148
             A+ T E     EK GL
Sbjct: 767  -AMATAE---ITEKLGL 729
>12443
          Length = 837

 Score = 43.1 bits (100), Expect = 9e-05,   Method: Compositional matrix adjust.
 Identities = 33/128 (25%), Positives = 63/128 (49%), Gaps = 9/128 (7%)
 Frame = -3

Query: 12  FKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVE----FATRSIQVDGKTI--KAQIW 65
           +KV+L+G +GVGK++ +++ T N+  L    T G++    +    I+  GKT+  + Q++
Sbjct: 580 YKVMLVGKTGVGKTSTVAKLTGNDIPLTHNETPGLQTSHLYWPGKIKHLGKTVLFQIQLF 401

Query: 66  DTAGQ---ERYRAITSAYYRGAVGALLVYDIAKHLTYENVERWLKELRDHADSNIVIMLV 122
           D AG+   +RY  I  A   G  G + ++      +++ + + L       D  I  + +
Sbjct: 400 D-AGETALKRYDHILPACQDGVDGIMFLFSFVDKGSFDEIPQLLTRFTTLEDG-ICKIAL 227

Query: 123 GNKSDLRH 130
           G K    H
Sbjct: 226 GTKYPFPH 203
>08153
          Length = 1703

 Score = 41.2 bits (95), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 33/122 (27%), Positives = 56/122 (45%), Gaps = 6/122 (4%)
 Frame = +1

Query: 13  KVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIQVDGKTIKAQIWDTAGQER 72
           +++++G    GK+ +L +    E  + +  TIG    T    V+ K I   +WD  GQ++
Sbjct: 88  RILMVGLDAAGKTTILYKLKLGEI-VTTIPTIGFNVET----VEYKNISFTVWDVGGQDK 252

Query: 73  YRAITSAYYRGAVGALLVYDIAK----HLTYENVERWLKE--LRDHADSNIVIMLVGNKS 126
            R +   Y++   G + V D       +   E + R L E  LRD      +I++  NK 
Sbjct: 253 IRPLWRHYFQNTQGLIFVVDSNDRERINEAKEELARMLNEDDLRDA-----IILVFANKQ 417

Query: 127 DL 128
           DL
Sbjct: 418 DL 423
>25796
          Length = 422

 Score = 38.5 bits (88), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 15/27 (55%), Positives = 19/27 (70%)
 Frame = -1

Query: 5  DDEYDYLFKVVLIGDSGVGKSNLLSRF 31
           + YDYLFK ++IG +G GKS LL  F
Sbjct: 86 SETYDYLFKFLIIGSAGSGKSCLLHHF 6
>10862
          Length = 2896

 Score = 38.1 bits (87), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 19/66 (28%), Positives = 31/66 (46%), Gaps = 1/66 (1%)
 Frame = -3

Query: 64   IWDTAGQERYRAITSAYYRGAVGALLVYDIAKHLTYENVERWLKE-LRDHADSNIVIMLV 122
            +WD  GQ++ R +   YY G  G + V D A     +   + L   + D    + +I++ 
Sbjct: 2474 VWDVGGQDKIRPLWRHYYTGTQGLIFVVDCADRDRIDEARQELHRIINDREMRDAIILIF 2295

Query: 123  GNKSDL 128
             NK DL
Sbjct: 2294 ANKQDL 2277
>33605
          Length = 888

 Score = 36.6 bits (83), Expect = 0.009,   Method: Compositional matrix adjust.
 Identities = 21/92 (22%), Positives = 43/92 (46%)
 Frame = +1

Query: 13  KVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIQVDGKTIKAQIWDTAGQER 72
           +++++G    GK+ +L +F   + +  S  T+G    T    ++ +  K  +WD  GQ+ 
Sbjct: 502 RLLMLGLDNAGKTTILKKFNGEDIDTIS-PTLGFNIKT----LEHRGFKLNVWDVGGQQS 666

Query: 73  YRAITSAYYRGAVGALLVYDIAKHLTYENVER 104
            R+    Y+    G + V D A  +   + +R
Sbjct: 667 LRSYWRNYFESTDGLVWVVDSADRMRIADCKR 762
>31932
          Length = 437

 Score = 35.0 bits (79), Expect = 0.021,   Method: Compositional matrix adjust.
 Identities = 21/59 (35%), Positives = 32/59 (54%), Gaps = 1/59 (1%)
 Frame = -1

Query: 115 SNIVIMLVGNKSDLRHLRAVPTDEARAFA-EKNGLSFIETSALDSTNVEAAFQTILTEI 172
           S +  +L+GNKSDL H R V  DE      E + L + ETS  D T ++ +   ++ E+
Sbjct: 407 STVPCLLLGNKSDLGH-REVEQDEIEDLCKEHDFLGWSETSVKDGTMIDESMNYLIEEM 234
>22318
          Length = 808

 Score = 26.9 bits (58), Expect = 5.7,   Method: Compositional matrix adjust.
 Identities = 13/23 (56%), Positives = 15/23 (65%)
 Frame = +3

Query: 13  KVVLIGDSGVGKSNLLSRFTRNE 35
           +V LIG   VGKS LLS  T+ E
Sbjct: 243 RVALIGFPSVGKSTLLSTLTKTE 311
>11062
          Length = 1716

 Score = 26.6 bits (57), Expect = 7.5,   Method: Compositional matrix adjust.
 Identities = 11/29 (37%), Positives = 19/29 (65%)
 Frame = +2

Query: 74  RAITSAYYRGAVGALLVYDIAKHLTYENV 102
           + +T   +RG++G+ L+Y+  K L  ENV
Sbjct: 74  KIVTLRQFRGSLGSFLLYNETKSLFSENV 160
>06883
          Length = 1257

 Score = 26.2 bits (56), Expect = 9.4,   Method: Compositional matrix adjust.
 Identities = 11/29 (37%), Positives = 19/29 (65%)
 Frame = +3

Query: 74  RAITSAYYRGAVGALLVYDIAKHLTYENV 102
           + +T   +RG++G+ L+Y+  K L  ENV
Sbjct: 72  KIVTLRQFRGSLGSFLLYNETKSLFSENV 158
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|41054974|ref|NP_955763.1| nuclear protein
localization 4 [Mus musculus]
         (576 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

19799                                                                 154   7e-38
17685                                                                  31   1.3  
15910                                                                  31   1.6  
18066                                                                  30   3.2  
15898                                                                  28   8.0  
>19799
          Length = 468

 Score =  154 bits (390), Expect = 7e-38,   Method: Compositional matrix adjust.
 Identities = 77/147 (52%), Positives = 94/147 (63%), Gaps = 34/147 (23%)
 Frame = -2

Query: 377 DNQVHFEGYQVSNQCMALVRDECLLPCKDAPELGYAKESSSEQYVPDVFYKDIDKFGNEI 436
           +NQ+HFEGYQVSNQCMAL RD+CL+P KD PELGY KESS+EQYVPDVFYK  D + NE+
Sbjct: 443 NNQIHFEGYQVSNQCMALERDDCLIPTKDVPELGYVKESSNEQYVPDVFYKGKDSYSNEV 264

Query: 437 TQLARPLPVEYLIID----------------------------------DFHSLATYLSQ 462
           T LARPLPVEYL++D                                  DF +L  Y+ Q
Sbjct: 263 THLARPLPVEYLLVDMPAAFPSDFQYTFKTQDSMNSFPAENREQMGETQDFGALVQYMQQ 84

Query: 463 NTSSVFLDTISDFHLLLFLVTNEVMPL 489
            + S FL  +SDFHLLLFL T+E++P+
Sbjct: 83  FSPSQFLQAMSDFHLLLFLCTSEIIPV 3
>17685
          Length = 1595

 Score = 31.2 bits (69), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 14/40 (35%), Positives = 19/40 (47%)
 Frame = +3

Query: 537  FGAVGGSARAATSAMWACQHCTFMNQPGTGHCEMCSLPRT 576
             G V G+    T+  WAC  CT +N     +C  C  P+T
Sbjct: 978  LGWVQGNHATNTTEEWACSVCTLLNPATQTNCTACLNPQT 1097
>15910
          Length = 1361

 Score = 30.8 bits (68), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 21/73 (28%), Positives = 31/73 (42%)
 Frame = +2

Query: 147 FDEDYLNHLEPPVKHMSFHAYIRKLTGGADKGKFVALENISCKIKSGCEGHLPWPNGICT 206
           FDE+Y + +    K +     +RKL     K +  A E +           LPW  G+ T
Sbjct: 827 FDEEYWSEISENAKDV-----VRKLLVIDPKKRLTATEAL----------RLPWVKGVAT 961

Query: 207 KCQPSAITLNRQK 219
           K     IT+N+ K
Sbjct: 962 KTTNMEITMNKLK 1000
>18066
          Length = 480

 Score = 29.6 bits (65), Expect = 3.2,   Method: Composition-based stats.
 Identities = 13/44 (29%), Positives = 24/44 (54%), Gaps = 3/44 (6%)
 Frame = +3

Query: 194 CEGHL---PWPNGICTKCQPSAITLNRQKYRHVDNIMFENHTVA 234
           C+G +   PW +  C K  PS      +K + +D+I++ +H V+
Sbjct: 21  CKGKVSTYPWSSSSCCKWVPSHRIGEGRKVKQMDSILYTDHVVS 152
>15898
          Length = 1199

 Score = 28.5 bits (62), Expect = 8.0,   Method: Compositional matrix adjust.
 Identities = 12/36 (33%), Positives = 20/36 (55%)
 Frame = -2

Query: 233 VADRFLDFWRKTGNQHFGYLYGRYTEHKDIPLGIRA 268
           + ++ L  WR T +   G   G++T+H D+  GI A
Sbjct: 502 LTEQLLHSWRHTSHIDAGTKRGKWTQHSDLGFGIIA 395
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|172072657|ref|NP_064382.3|
alpha-1,3-mannosyltransferase ALG2 [Mus musculus]
         (415 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

29615                                                                 153   9e-38
20872                                                                  32   0.32 
18867                                                                  30   2.2  
20597                                                                  29   3.2  
21988                                                                  29   4.0  
07719                                                                  28   5.6  
>29615
          Length = 356

 Score =  153 bits (387), Expect = 9e-38,   Method: Compositional matrix adjust.
 Identities = 74/122 (60%), Positives = 93/122 (76%), Gaps = 2/122 (1%)
 Frame = +2

Query: 51  TAHYDPNHCFIETRE--LSVQCAGDWLPRSLGWGGRGAAICSYVRMVFLALYVLFLSGEE 108
           TAH+DP+HCF ETR+  L V   GDWLPRS+   GR  A+C+YVRM+++AL +++ SG  
Sbjct: 2   TAHHDPSHCFQETRDGTLEVVAVGDWLPRSVL--GRCQALCAYVRMIYVALCLVYFSGHP 175

Query: 109 FDVVVCDQVSACIPVFKLARRRKRVLFYCHFPDLLLTQRNSALKKFYRAPIDWIEEYTTG 168
            D++ CDQ+SAC+PV K  R   +VLFYCHFPDLLLT R S LK+ YRAPIDW+EE TTG
Sbjct: 176 CDLIFCDQISACMPVLK--RSGHKVLFYCHFPDLLLTARTSPLKRLYRAPIDWLEERTTG 349

Query: 169 MA 170
           MA
Sbjct: 350 MA 355
>20872
          Length = 710

 Score = 32.3 bits (72), Expect = 0.32,   Method: Compositional matrix adjust.
 Identities = 22/64 (34%), Positives = 31/64 (48%), Gaps = 4/64 (6%)
 Frame = +1

Query: 306 RQKISLLHGCLCVLYTPSNEHFGIVPLEAMYMQCPVIAVNNGGPLESIV----HKVTGFL 361
           R+   LL   +  L+   NEHFGI  +E M     ++A ++GGP   IV       TGFL
Sbjct: 175 RELKHLLASSVIGLHAMWNEHFGIGVVECMAAGTVILAHDSGGPKLDIVVPHNDAPTGFL 354

Query: 362 CEPD 365
              +
Sbjct: 355 ASTE 366
>18867
          Length = 444

 Score = 29.6 bits (65), Expect = 2.2,   Method: Compositional matrix adjust.
 Identities = 21/66 (31%), Positives = 30/66 (45%), Gaps = 3/66 (4%)
 Frame = +3

Query: 240 LPLALRSLVQLRNRLPSQEWDKVHLFMAGGYDDRIPENVEHYKELKKMVQES---DLERH 296
           LP+       L+  LP +    V  F    +D+R+P  + HY  L  +   S   DL RH
Sbjct: 123 LPIHSSMYRNLKTNLPKE----VMSFPDCDFDNRLPSFISHYDVLNYLKDYSVKFDLLRH 290

Query: 297 VTFLRS 302
           + F RS
Sbjct: 291 IQFQRS 308
>20597
          Length = 1474

 Score = 29.3 bits (64), Expect = 3.2,   Method: Compositional matrix adjust.
 Identities = 19/56 (33%), Positives = 28/56 (50%), Gaps = 1/56 (1%)
 Frame = +2

Query: 32  LVLDAALALQEYGCDVKIWTAHYDPNHCFIETRELSVQ-CAGDWLPRSLGWGGRGA 86
           L+L    ++++ GCD+  WT      H  +  R+ SVQ C+GD L      G RG 
Sbjct: 665 LLLLTT*SIEQPGCDLPCWTQVCSLLHRLVYIRDTSVQ*CSGDTLKWVGARGDRGG 832
>21988
          Length = 568

 Score = 28.9 bits (63), Expect = 4.0,   Method: Compositional matrix adjust.
 Identities = 10/21 (47%), Positives = 16/21 (76%)
 Frame = -3

Query: 218 DLVPKGKQFLFLSINRYERKK 238
           +L+   + F+F++INRYE KK
Sbjct: 461 NLISSARLFIFITINRYEHKK 399
>07719
          Length = 1773

 Score = 28.5 bits (62), Expect = 5.6,   Method: Compositional matrix adjust.
 Identities = 13/39 (33%), Positives = 22/39 (56%), Gaps = 2/39 (5%)
 Frame = -2

Query: 303  FSDRQKISLLHGCLCVLYTPSNEHFGIVPLEA--MYMQC 339
            F   +K+  LH  LC+ Y+P N HF +  L    ++++C
Sbjct: 1061 FQMEKKLKSLHE*LCIYYSPENYHFVLCNLNTGNLHVEC 945
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|170763481|ref|NP_083781.2| adaptor-related protein
complex 3, mu 2 subunit [Mus musculus]
         (418 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

04701                                                                 139   1e-37
08361                                                                  84   1e-16
29016                                                                  49   5e-06
28998                                                                  48   8e-06
06056                                                                  40   0.002
04375                                                                  32   0.47 
>04701
          Length = 4543

 Score =  139 bits (350), Expect(2) = 1e-37,   Method: Compositional matrix adjust.
 Identities = 96/345 (27%), Positives = 158/345 (45%), Gaps = 16/345 (4%)
 Frame = +2

Query: 90  FQDYFGVCSEPVIKDNXXXXXXXXXXMLDNGFPLATESNILKELIKPPTILRTVVNTITG 149
           F +YF    E  I+DN          ++D G+P  T+S IL+E I           T  G
Sbjct: 356 FVEYFKELEEESIRDNFVIIYELLDEVMDFGYPQTTDSKILQEYI-----------TQEG 502

Query: 150 ST-NVGDQLPTGQLSVVPWRRTGVKYTNNEAYFDVVEEIDAIIDKSGSTVTAEIQGVIDA 208
               V  + P    + V WR  GVKY  NE + DV+E ++ ++  +G+ + +EI G +  
Sbjct: 503 QKLEVAPRPPMAVTNAVSWRSEGVKYRKNEVFLDVIESVNLLVSANGNVLRSEIVGSVKM 682

Query: 209 CVKLTGMPDLTLSFMNPRL-------------LDDVSFHPCVRFKRWESERILSFIPPDG 255
            V L+GMP+L L   +  L             L+DV FH CVR  R+E++R +SFIPPDG
Sbjct: 683 RVFLSGMPELRLGLNDKVLFESTGRGKSKSVELEDVKFHQCVRLSRFENDRTISFIPPDG 862

Query: 256 NFRLLAYHVSAQNLVAIPVYVKHSISFRDSSSLGRFEITVGPKQTMGKTIEGVIVTSQMP 315
            F L++Y +   N    P+    S+  R   S   + I    +     T   V +   +P
Sbjct: 863 EFELMSYRL---NTHVKPLIWVESVIERHVHSRVEYMIKAKSQFKRRSTANNVEIIIPVP 1033

Query: 316 KGVLNMSLTPSQGTHTFDPVTKMLSWDVGKINPQKLPSLKGTMGL-QVGASKPDENPTIN 374
               +     + G+  + P    + W +      K   ++   GL  V     +  P I+
Sbjct: 1034ADADSPKFKTTVGSCKYVPEINSVIWSIKSFPGGKEFLMRAHFGLPSVENEDAEGRPPIS 1213

Query: 375 LQFKIQQLAISGLKVNRLDMYGEK-YKPFKGIKYMTKAGKFQVRT 418
           ++F+I    +SG++V  L +  +  Y+    ++Y+T+ G +Q+RT
Sbjct: 1214IKFEIPYFTVSGIQVRYLKIIEKSGYQALPWVRYITQNGDYQLRT 1348

 Score = 35.0 bits (79), Expect(2) = 1e-37,   Method: Compositional matrix adjust.
 Identities = 15/84 (17%), Positives = 40/84 (47%)
 Frame = +3

Query: 4   SLFLINSSGDIFLEKHWKSVVSRSVCDYFFEAQERATEAENVPPVIPTPHHYLLSVYRHK 63
           ++++++  G + + ++++  +  SV D F        +  NV P+I   +   + +  + 
Sbjct: 99  AIYILDVKGKVLISRNYRGDIDMSVIDKFMPLVMEGEDDSNVTPIISHGNVTFVYIKYNN 278

Query: 64  IFFVAVIQTEVPPLFVIEFLHRVV 87
           ++ V+  +       V  FLH++V
Sbjct: 279 LYLVSTTRKNANVALVFSFLHKLV 350
>08361
          Length = 465

 Score = 83.6 bits (205), Expect = 1e-16,   Method: Compositional matrix adjust.
 Identities = 48/149 (32%), Positives = 75/149 (50%)
 Frame = -3

Query: 81  EFLHRVVDTFQDYFGVCSEPVIKDNXXXXXXXXXXMLDNGFPLATESNILKELIKPPTIL 140
           EFLH++ +  Q YFG  SE  IK+N          +LD G+P  T++ ILK  I    I 
Sbjct: 460 EFLHKIAEVMQAYFGKISEENIKNNFVLIYEILDEILDYGYPQNTDTGILKTFITQQGIK 281

Query: 141 RTVVNTITGSTNVGDQLPTGQLSVVPWRRTGVKYTNNEAYFDVVEEIDAIIDKSGSTVTA 200
                +   +  +  Q+ TGQ   + WRR G+KY  NE + DV+E ++ ++   G  ++A
Sbjct: 280 S---QSKEDTAQITSQV-TGQ---IGWRREGIKYRRNELFLDVLESVNLLMSPQGQVLSA 122

Query: 201 EIQGVIDACVKLTGMPDLTLSFMNPRLLD 229
            + G I     L+GMP+      +  L+D
Sbjct: 121 HVAGRIVMKSYLSGMPECKFGINDKVLMD 35
>29016
          Length = 550

 Score = 48.5 bits (114), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 17/34 (50%), Positives = 25/34 (73%)
 Frame = +2

Query: 228 LDDVSFHPCVRFKRWESERILSFIPPDGNFRLLA 261
           +DD  FH CV+  ++E+E  +SFIPPDG F L++
Sbjct: 29  IDDCQFHQCVKLSKFETEHSISFIPPDGEFELMS 130
>28998
          Length = 569

 Score = 47.8 bits (112), Expect = 8e-06,   Method: Compositional matrix adjust.
 Identities = 17/33 (51%), Positives = 24/33 (72%)
 Frame = +2

Query: 228 LDDVSFHPCVRFKRWESERILSFIPPDGNFRLL 260
           +DD  FH CV+  ++E+E  +SFIPPDG F L+
Sbjct: 29  IDDCQFHQCVKLSKFETEHSISFIPPDGEFELM 127
>06056
          Length = 1228

 Score = 40.0 bits (92), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 14/31 (45%), Positives = 20/31 (64%)
 Frame = -3

Query: 228  LDDVSFHPCVRFKRWESERILSFIPPDGNFR 258
            +DD  FH CV+  ++E+E  +SFIP  GN  
Sbjct: 1175 IDDCQFHQCVKLSKFETEHSISFIPLXGNLN 1083
>04375
          Length = 2667

 Score = 32.0 bits (71), Expect = 0.47,   Method: Compositional matrix adjust.
 Identities = 19/69 (27%), Positives = 30/69 (43%), Gaps = 1/69 (1%)
 Frame = +3

Query: 64  IFFVAVIQTEVPPLFVIEFLHRVVDTFQDYFG-VCSEPVIKDNXXXXXXXXXXMLDNGFP 122
           ++F   I+ E   L  +E +HR V+    YFG VC   +I +           ML     
Sbjct: 294 LYFCCAIEPEDNELLTLEIIHRYVELLDKYFGSVCELDIIFNFEKAFFMLDEFMLGGEVQ 473

Query: 123 LATESNILK 131
             ++ N+LK
Sbjct: 474 ETSKKNVLK 500
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|30525051|ref|NP_766189.1| RAB2B protein [Mus
musculus]
         (216 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

08428                                                                 152   1e-37
34468                                                                 124   4e-29
33374                                                                 124   4e-29
01398                                                                 119   9e-28
26083                                                                 107   4e-24
17511                                                                 105   1e-23
05468                                                                 104   3e-23
30760                                                                 103   4e-23
14456                                                                  97   4e-21
07580                                                                  94   3e-20
07465                                                                  93   8e-20
01095                                                                  92   2e-19
33380                                                                  92   2e-19
33794                                                                  91   3e-19
13901                                                                  87   7e-18
11257                                                                  86   1e-17
13750                                                                  85   2e-17
32723                                                                  83   1e-16
01972                                                                  76   3e-16
19006                                                                  81   3e-16
29380                                                                  77   4e-15
34597                                                                  71   7e-14
12339                                                                  72   1e-13
26536                                                                  71   3e-13
35581                                                                  70   7e-13
14119                                                                  69   2e-12
11728                                                                  69   2e-12
27191                                                                  68   2e-12
00858                                                                  67   7e-12
13745                                                                  66   1e-11
34359                                                                  62   2e-10
19656                                                                  60   5e-10
25618                                                                  57   5e-09
09204                                                                  56   9e-09
14775                                                                  53   9e-08
10708                                                                  36   2e-06
08153                                                                  45   3e-05
00552                                                                  44   5e-05
33605                                                                  42   1e-04
31291                                                                  42   1e-04
10862                                                                  42   2e-04
25796                                                                  40   5e-04
18509                                                                  40   7e-04
09827                                                                  39   0.002
31932                                                                  35   0.020
25727                                                                  30   1.0  
33890                                                                  29   1.6  
>08428
          Length = 1109

 Score =  152 bits (384), Expect = 1e-37,   Method: Compositional matrix adjust.
 Identities = 69/160 (43%), Positives = 104/160 (65%)
 Frame = -3

Query: 8    KYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMVNIDGKQIKLQIWDTAGQES 67
            K  ++GD+GVGKS ++L+F    ++P  + TIG  F ++ + +DG   + QIWDTAGQE 
Sbjct: 1065 KVCLLGDSGVGKSSIVLRFVTGSYRPSQESTIGASFMSKSLVVDGAGYRFQIWDTAGQEK 886

Query: 68   FRSITRSYYRGAAGALLVYDITRRETFNHLTSWLEDARQHSSSNMVIMLIGNKSDLESRR 127
            FR++   YYRGAA A++VYD+TR  TF  + SW+++ R     N+V+ + GNK DLE  R
Sbjct: 885  FRALAPMYYRGAAAAVIVYDVTRPRTFKSVKSWIQELRSFGPPNIVLAIAGNKCDLEELR 706

Query: 128  DVKREEGEAFAREHGLIFMETSAKTACNVEEAYINTAKEI 167
            +V  ++ + +A     IF ETSA TA NVEE +   A+++
Sbjct: 705  EVVEKDAQEYASSISAIFGETSAMTAVNVEEMFTELARQL 586
>34468
          Length = 1502

 Score =  124 bits (310), Expect = 4e-29,   Method: Compositional matrix adjust.
 Identities = 61/167 (36%), Positives = 101/167 (60%), Gaps = 5/167 (2%)
 Frame = +1

Query: 6   LFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMVNIDGKQIKLQIWDTAGQ 65
           +FK I+IGD+ VGK+CL  +F   +F    + TIGV+F  + + +D + +KLQ+WDTAGQ
Sbjct: 493 IFKIIVIGDSNVGKTCLTYRFCLGKFPDKTEATIGVDFREKSIQVDSEHLKLQLWDTAGQ 672

Query: 66  ESFR-SITRSYYRGAAGALLVYDITRRETFNHLTSWLEDARQHSSSNMVI-MLIGNKSDL 123
           E FR S+ + YYR     + VYD+T+  +F ++ +W+E+  +H+ +  +  +L+GNK D+
Sbjct: 673 ERFRKSMVQHYYRNVHAVVFVYDMTKMSSFENMPAWIEECDRHNLTKYIPRILVGNKCDV 852

Query: 124 ESRRDVKREEGEAFAREHGLIFMETSAK---TACNVEEAYINTAKEI 167
             R  V     + FA  H +   ETSAK    A +V+  ++  A ++
Sbjct: 853 VERIAVNTNLAQKFADAHNMPLFETSAKDDEKANHVDAIFMTVAHKL 993
>33374
          Length = 489

 Score =  124 bits (310), Expect = 4e-29,   Method: Compositional matrix adjust.
 Identities = 56/116 (48%), Positives = 83/116 (71%)
 Frame = +1

Query: 43  FGARMVNIDGKQIKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRETFNHLTSWLE 102
           F  + V +D   +K +IWDTAGQE + S+   YYRGA  A++VYDIT ++TF    +W++
Sbjct: 139 FLTQTVCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNQDTFGRAKTWVK 318

Query: 103 DARQHSSSNMVIMLIGNKSDLESRRDVKREEGEAFAREHGLIFMETSAKTACNVEE 158
           + ++ +S N+VI L GNK+DL ++R V+ EE +A+A E+ L+FMETSAKTA NV +
Sbjct: 319 ELQRQASPNIVIALAGNKADLANKRMVEFEEAQAYAEENSLLFMETSAKTAMNVND 486

 Score = 37.4 bits (85), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 18/52 (34%), Positives = 30/52 (57%)
 Frame = +2

Query: 7  FKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMVNIDGKQIKLQ 58
          FK +++G++ VGKS L+L+F   +F    + TIG  F  R   +  +Q  L+
Sbjct: 32 FKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAF*LRQFVLMTQQSSLR 187
>01398
          Length = 1421

 Score =  119 bits (298), Expect = 9e-28,   Method: Compositional matrix adjust.
 Identities = 65/156 (41%), Positives = 89/156 (57%), Gaps = 4/156 (2%)
 Frame = -2

Query: 65   QESFRSITRSYYRGAAGALLVYDITRRETFNHLTSWLEDARQHSSSNMVIMLI-GNKSDL 123
            QE FRSITRSYYR + G ++VYDIT+R TF +L  W E+AR H   +  I L+ G+KSD 
Sbjct: 1420 QERFRSITRSYYRNSVGVIIVYDITKRSTFENLKQWYEEARNHIEPHKAIFLVLGHKSDR 1241

Query: 124  ESRRDVKREEGEAFAREHGLIFMETSAKTACNVEEAYINTAKEIYRKIQQGLFDVHNEAN 183
            E  R V   EG  FA  HGL F ETSAK+  N+E+ +   AK+ Y+ +Q G   +    +
Sbjct: 1240 EDARQVTAREGRRFAEMHGLKFFETSAKSGHNIEDVFAQIAKDTYQHLQDGHIRLEEGWD 1061

Query: 184  GIKIG---PQQSITSSVGPCSPQQNVSDIGPDSGCC 216
            G+K G   P++++  + G  S            GCC
Sbjct: 1060 GVKQGFARPRETVHLAEGEES-----------GGCC 986
>26083
          Length = 432

 Score =  107 bits (267), Expect = 4e-24,   Method: Compositional matrix adjust.
 Identities = 46/114 (40%), Positives = 77/114 (67%)
 Frame = +1

Query: 7   FKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMVNIDGKQIKLQIWDTAGQE 66
           FK + +G+  VGK+ L+ +F    F   +  TIG++F ++ + ++ + I+LQ+WDTAGQE
Sbjct: 79  FKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTIRLQLWDTAGQE 258

Query: 67  SFRSITRSYYRGAAGALLVYDITRRETFNHLTSWLEDARQHSSSNMVIMLIGNK 120
            FRS+  SY R ++ A++VYDIT   +F+  + W++D R    S+++IML+GNK
Sbjct: 259 RFRSLIPSYIRDSSVAVVVYDITNANSFHQTSKWIDDVRTERGSDVIIMLVGNK 420
>17511
          Length = 483

 Score =  105 bits (263), Expect = 1e-23,   Method: Compositional matrix adjust.
 Identities = 53/122 (43%), Positives = 76/122 (62%), Gaps = 4/122 (3%)
 Frame = -3

Query: 6   LFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMVNIDGKQIKLQIWDTAGQ 65
           L K II+GD+GVGK+ L+ Q+ +K+F   +  TIG +F  + V +D + + +QIWDTAGQ
Sbjct: 367 LLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQIWDTAGQ 188

Query: 66  ESFRSITRSYYRGAAGALLVYDITRRETFNHLTSW----LEDARQHSSSNMVIMLIGNKS 121
           E F+S+  ++YRGA   +LV+D+T   TF  L SW    L  A      N   ++IGNK 
Sbjct: 187 ERFQSLGVAFYRGADCCVLVFDVTMPNTFRSLDSWRDEFLIQASPRDPENFPFVVIGNKI 8

Query: 122 DL 123
           DL
Sbjct: 7   DL 2
>05468
          Length = 1558

 Score =  104 bits (260), Expect = 3e-23,   Method: Compositional matrix adjust.
 Identities = 59/162 (36%), Positives = 94/162 (58%), Gaps = 7/162 (4%)
 Frame = -3

Query: 5    YLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMVNIDGKQ-IKLQIWDTA 63
            +L+K ++IG+ G GK+ ++ ++  + F   +  TIGV+F  +++N D    I+LQ+WD A
Sbjct: 1544 HLYKILVIGELGTGKTSIIKRYVHQFFSQHYRATIGVDFALKVLNWDADTLIRLQLWDIA 1365

Query: 64   GQESFRSITRSYYRGAAGALLVYDITRRETFNHLTSWLED----ARQHSSSNMVIMLIGN 119
            GQE F ++TR YY+ A GA +V+D+TR  TF+ +T W  D     +    S +  +L+ N
Sbjct: 1364 GQERFGNMTRVYYKEAVGAFVVFDVTRASTFDAVTKWKNDLDSKVQLADGSPVPCVLLAN 1185

Query: 120  KSDLESRRDVKR-EEGEAFAREHGLI-FMETSAKTACNVEEA 159
            K D      V    + + F  E G I + ETSAK   N++EA
Sbjct: 1184 KCDQAKEGLVNNTSQMDEFCSEKGFIGWYETSAKENINIDEA 1059
>30760
          Length = 596

 Score =  103 bits (258), Expect = 4e-23,   Method: Compositional matrix adjust.
 Identities = 60/174 (34%), Positives = 95/174 (54%), Gaps = 6/174 (3%)
 Frame = -1

Query: 8   KYIIIGDTGVGKS--CLLLQFTDKRFQPVHDLTIGVEFGARMVNIDGK--QIKLQIWDTA 63
           K I+ GD+GVGKS  C +       F   + +T GVE   ++VNI     Q++L ++D+A
Sbjct: 524 KCIVTGDSGVGKSSICQVFHSDSAHFPKNYSMTTGVEVLVKLVNIPDSRDQVELYLFDSA 345

Query: 64  GQESFRSITRSYYRGAAGALLVYDITRRETFNHLTSWLEDARQHSSSNMVI--MLIGNKS 121
           G+E F      ++   +  ++VYD+T   +F+    WLE  R  +  N VI  +L+ NK+
Sbjct: 344 GKEIFSENVTKFWDQPSVVMVVYDVTDETSFSGCVRWLERVRA-AKPNTVIPGVLVANKT 168

Query: 122 DLESRRDVKREEGEAFAREHGLIFMETSAKTACNVEEAYINTAKEIYRKIQQGL 175
           DL+ RR V R+EG+  A+ HGL + E SAK   N +  +   A   ++  Q+ L
Sbjct: 167 DLDERRRVSRKEGKDLAQSHGLEYFECSAKEMQNTDTPFFCLAHAFHKLYQEQL 6
>14456
          Length = 1867

 Score = 97.4 bits (241), Expect = 4e-21,   Method: Compositional matrix adjust.
 Identities = 56/157 (35%), Positives = 88/157 (56%), Gaps = 5/157 (3%)
 Frame = -1

Query: 16   GVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMVNIDGKQIKLQIWDTAGQESFRSITRSY 75
            GVGKS L+ +F   +F      TIGVEF  + V +D +   +QIWDTAGQE F+S+   +
Sbjct: 1111 GVGKSSLMNRFVSNKFDAQSFHTIGVEFLNKDVVVDDETYTMQIWDTAGQERFKSLRTPF 932

Query: 76   YRGAAGALLVYDITRRETFNHLTSWLED----ARQHSSSNMVIMLIGNKSDLESRRDVKR 131
            YRGA   LL + +   ++F +L+ W ++    A          +++GNK D+E R+ V  
Sbjct: 931  YRGADCCLLTFSVDSMQSFRNLSMWRKEFLYYADIQDGVTFPFVVLGNKIDVEGRQ-VTN 755

Query: 132  EEGEAFAREH-GLIFMETSAKTACNVEEAYINTAKEI 167
            EE  ++   +    + ETSAK A NVE+A++   + +
Sbjct: 754  EEARSWCTANSNAPYFETSAKDATNVEKAFLAAVQRL 644
>07580
          Length = 921

 Score = 94.4 bits (233), Expect = 3e-20,   Method: Compositional matrix adjust.
 Identities = 48/126 (38%), Positives = 73/126 (57%), Gaps = 1/126 (0%)
 Frame = +3

Query: 46  RMVNIDGKQIKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRETFNHLTSWLED-A 104
           + V +DG+Q  L+I DTAG E F ++   Y +   G LL Y IT + TFN L    E   
Sbjct: 177 KQVEVDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFLLAYSITAQSTFNDLQELREQIL 356

Query: 105 RQHSSSNMVIMLIGNKSDLESRRDVKREEGEAFAREHGLIFMETSAKTACNVEEAYINTA 164
           R   + ++ ++L+GNK DLE  R V +++G+  AR     F+ETSAK   NV E +++  
Sbjct: 357 RVKDTDDVPMLLVGNKCDLEDERVVGKDQGQGLARSFSCAFLETSAKARINVNEIFMDLV 536

Query: 165 KEIYRK 170
           ++I +K
Sbjct: 537 RQINKK 554
>07465
          Length = 1103

 Score = 93.2 bits (230), Expect = 8e-20,   Method: Compositional matrix adjust.
 Identities = 54/177 (30%), Positives = 93/177 (52%)
 Frame = +3

Query: 20  SCLLLQFTDKRFQPVHDLTIGVEFGARMVNIDGKQIKLQIWDTAGQESFRSITRSYYRGA 79
           S ++ ++    F   +  TIGV+F  R + + G+ ++L +WDTAGQE F +IT++YYRGA
Sbjct: 240 SSMIQRYCKGIFTKDYKKTIGVDFLERQIEVGGEDVRLMLWDTAGQEEFDAITKAYYRGA 419

Query: 80  AGALLVYDITRRETFNHLTSWLEDARQHSSSNMVIMLIGNKSDLESRRDVKREEGEAFAR 139
              +L +    R++F  L +W     +     + ++++ NK DL     V+ EE E  A+
Sbjct: 420 QACVLAFSTVDRDSFEALETWKRKV-EDEVGEIGMVIVQNKIDLIDDAVVRPEEAENLAK 596

Query: 140 EHGLIFMETSAKTACNVEEAYINTAKEIYRKIQQGLFDVHNEANGIKIGPQQSITSS 196
           +  L F  TS K   NV+E +   A +   ++  G+ +V+     I  G  Q+ T +
Sbjct: 597 KLRLRFYRTSVKENMNVDEVFRYLADKYLHQLNTGMDEVNLTPQKIGQGLIQTETKN 767
>01095
          Length = 1745

 Score = 91.7 bits (226), Expect = 2e-19,   Method: Compositional matrix adjust.
 Identities = 46/117 (39%), Positives = 76/117 (64%)
 Frame = -1

Query: 84   LVYDITRRETFNHLTSWLEDARQHSSSNMVIMLIGNKSDLESRRDVKREEGEAFAREHGL 143
            +VYDIT ++TF    +W+++ ++ +S N+VI L GNK+DL ++R V+ EE +A+A E+ L
Sbjct: 1745 VVYDITNQDTFGRAKTWVKELQRQASPNIVIALAGNKADLANKRMVEFEEAQAYAEENSL 1566

Query: 144  IFMETSAKTACNVEEAYINTAKEIYRKIQQGLFDVHNEANGIKIGPQQSITSSVGPC 200
            +FMETSAKTA NV + ++  AK++ +   +G         G+++  +QS  S  G C
Sbjct: 1565 LFMETSAKTAMNVNDIFLAIAKKLPKN--EGGGGSQPRQQGVRLNNEQSQQSEGGCC 1401
>33380
          Length = 282

 Score = 91.7 bits (226), Expect = 2e-19,   Method: Compositional matrix adjust.
 Identities = 39/75 (52%), Positives = 54/75 (72%)
 Frame = +3

Query: 53  KQIKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRETFNHLTSWLEDARQHSSSNM 112
           K++KLQIWDTAGQE +R+IT +YYRGA G +L+YD+T  E+FN +  W    + +S  N 
Sbjct: 54  KRVKLQIWDTAGQERYRTITTAYYRGAMGFILMYDVTNEESFNAVQDWCTQIKTYSWDNA 233

Query: 113 VIMLIGNKSDLESRR 127
            ++L+GNK DLE  R
Sbjct: 234 QVVLVGNKCDLEDER 278
>33794
          Length = 779

 Score = 91.3 bits (225), Expect = 3e-19,   Method: Compositional matrix adjust.
 Identities = 44/125 (35%), Positives = 75/125 (60%)
 Frame = -1

Query: 41  VEFGARMVNIDGKQIKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRETFNHLTSW 100
           V +    + ++GK++KLQIWDT+GQ  F +I RSY RGA G +LVYDIT + +F+ +  W
Sbjct: 692 VAYKTTTILLEGKRVKLQIWDTSGQGRFCTIIRSYSRGAQGIILVYDITNKWSFDGIDRW 513

Query: 101 LEDARQHSSSNMVIMLIGNKSDLESRRDVKREEGEAFAREHGLIFMETSAKTACNVEEAY 160
           L++  +H +  +  +L+GN+  L  +R V  ++ E +A  + +   E S     N+ E++
Sbjct: 512 LKEVEEH-APGIPKVLVGNRLHLAYKRQVAAKQAETYASRNNMSCFEISPLCDFNIRESF 336

Query: 161 INTAK 165
              A+
Sbjct: 335 CELAR 321
>13901
          Length = 962

 Score = 86.7 bits (213), Expect = 7e-18,   Method: Compositional matrix adjust.
 Identities = 40/101 (39%), Positives = 65/101 (64%), Gaps = 1/101 (0%)
 Frame = -3

Query: 1   MTYAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMVNIDGK-QIKLQI 59
           M+   LFK IIIGD  VGK+  + ++ +  F+  + +TIGV+F  +++    K  IKLQ+
Sbjct: 303 MSEEVLFKVIIIGDPTVGKTSFVQRYVNDSFRRDYKMTIGVDFALKVIRWSDKCNIKLQL 124

Query: 60  WDTAGQESFRSITRSYYRGAAGALLVYDITRRETFNHLTSW 100
           WD AGQE F S+TR YY+ A   ++++D+T++ T+ +   W
Sbjct: 123 WDIAGQERFTSMTRVYYKDAHACIVMFDLTQKNTYQNAIRW 1
>11257
          Length = 1102

 Score = 85.9 bits (211), Expect = 1e-17,   Method: Compositional matrix adjust.
 Identities = 44/131 (33%), Positives = 76/131 (58%), Gaps = 5/131 (3%)
 Frame = -2

Query: 48   VNIDGKQIKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRETFNHLTSWLED---- 103
            V +DG+   +QIWDTAGQE ++S+   +YRG    LL + +   ++   L+ W ++    
Sbjct: 1047 VVVDGETFTMQIWDTAGQERYKSLRTPFYRGTDCCLLTFSVDNLKSLQSLSDWYDEFVNY 868

Query: 104  ARQHSSSNMVIMLIGNKSDLESRRDVKREEGEAFAREHG-LIFMETSAKTACNVEEAYIN 162
            A    S++   ++IGNK+D+E  R+V  E+   + R HG L + ETSAK + NV++A++ 
Sbjct: 867  ADIQDSASFPFVIIGNKADIEE-REVSSEDAYNWCRTHGNLPYFETSAKDSLNVQQAFLA 691

Query: 163  TAKEIYRKIQQ 173
              + +    +Q
Sbjct: 690  VVRRLREMDEQ 658
>13750
          Length = 503

 Score = 85.1 bits (209), Expect = 2e-17,   Method: Compositional matrix adjust.
 Identities = 52/149 (34%), Positives = 78/149 (52%), Gaps = 3/149 (2%)
 Frame = -2

Query: 19  KSCLLLQFTDKRFQPVHDLTIGV---EFGARMVNIDGKQIKLQIWDTAGQESFRSITRSY 75
           K+CLL ++    F      TI V   EF       D   ++  +WDT G E++RS+  S+
Sbjct: 502 KTCLLRRYQKGFFMDRTMPTIAVLCSEFNES--RTDPLNVRYTLWDTGGAETYRSLWVSH 329

Query: 76  YRGAAGALLVYDITRRETFNHLTSWLEDARQHSSSNMVIMLIGNKSDLESRRDVKREEGE 135
           +RGA  ALLVYD+T   +F   T+    A   +     ++ +G+K+DLE  R +  E G+
Sbjct: 328 FRGAQVALLVYDVTCEWSFLTATTVWRKALMKNIPEAQVIFVGSKTDLEENRVISTERGQ 149

Query: 136 AFAREHGLIFMETSAKTACNVEEAYINTA 164
           AFA + G  F ETS+ T  NV+  +   A
Sbjct: 148 AFATQCGYTFFETSSVTGKNVDAVFWEIA 62
>32723
          Length = 384

 Score = 82.8 bits (203), Expect = 1e-16,   Method: Compositional matrix adjust.
 Identities = 40/111 (36%), Positives = 67/111 (60%)
 Frame = +2

Query: 65  QESFRSITRSYYRGAAGALLVYDITRRETFNHLTSWLEDARQHSSSNMVIMLIGNKSDLE 124
           QE FRSIT+SYYR A   +LVYD+  ++++  L  W+ +   ++ + ++  L+GNK D  
Sbjct: 2   QERFRSITQSYYRSANALILVYDVCSQQSYESLPQWIHEIELYAGTKVLAFLVGNKIDQT 181

Query: 125 SRRDVKREEGEAFAREHGLIFMETSAKTACNVEEAYINTAKEIYRKIQQGL 175
            +R++    G+ FA  + + F+ETSAK A NVE+ +   A ++  + Q  L
Sbjct: 182 DKREIPTHIGKEFAERYEMRFLETSAKEADNVEKLFSTIAYQLTAQAQGTL 334
>01972
          Length = 2359

 Score = 76.3 bits (186), Expect(2) = 3e-16,   Method: Compositional matrix adjust.
 Identities = 39/130 (30%), Positives = 73/130 (56%)
 Frame = +3

Query: 38  TIGVEFGARMVNIDGKQIKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRETFNHL 97
           T+GVE    + +    ++K  +WDTAGQE F  +   YY     A++++D+T R T+ ++
Sbjct: 396 TLGVEVHPLLFHTSRGKLKFNVWDTAGQEKFGGLRDGYYIQGQCAVIMFDVTSRVTYKNV 575

Query: 98  TSWLEDARQHSSSNMVIMLIGNKSDLESRRDVKREEGEAFAREHGLIFMETSAKTACNVE 157
            +W  D  +    N+ I+L GNK D++ R+   + +   F R+  L + + SAK+  N E
Sbjct: 576 PNWHRDLVR-VCENIPIVLCGNKVDIKDRK--VKAKAIVFHRKKNLQYYDISAKSNYNFE 746

Query: 158 EAYINTAKEI 167
           + ++  A+++
Sbjct: 747 KPFLWLARKL 776

 Score = 25.0 bits (53), Expect(2) = 3e-16,   Method: Compositional matrix adjust.
 Identities = 8/17 (47%), Positives = 13/17 (76%)
 Frame = +1

Query: 7   FKYIIIGDTGVGKSCLL 23
           FK +++GD GVGK+  +
Sbjct: 304 FKLVLVGDGGVGKTTFV 354
>19006
          Length = 568

 Score = 80.9 bits (198), Expect = 3e-16,   Method: Compositional matrix adjust.
 Identities = 42/126 (33%), Positives = 70/126 (55%), Gaps = 1/126 (0%)
 Frame = -2

Query: 8   KYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMVNIDGKQIKLQIWDTAGQES 67
           K +I+GD   GK+CLL+ F+  +F  V+  T+   + A  + +D KQ++L +WDTAGQE 
Sbjct: 432 KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVAD-IEVDSKQVELALWDTAGQED 256

Query: 68  FRSITRSYYRGAAGALLVYDITRRETFNHLT-SWLEDARQHSSSNMVIMLIGNKSDLESR 126
           +  +    Y      L+ + I   ++  ++   W  + R H   N+ I+L+GNK DL + 
Sbjct: 255 YDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVR-HFCPNVPIILVGNKKDLRND 79

Query: 127 RDVKRE 132
            + KRE
Sbjct: 78  ENTKRE 61
>29380
          Length = 853

 Score = 77.4 bits (189), Expect = 4e-15,   Method: Compositional matrix adjust.
 Identities = 35/93 (37%), Positives = 64/93 (68%), Gaps = 1/93 (1%)
 Frame = -2

Query: 79  AAGALLVYDITRRETFNHLTSWLEDARQHSSSNMVIMLIGNKSDLESR-RDVKREEGEAF 137
           A+ A++VYD+   +TF+   +W+++ RQ ++ +++I+L GNK DL ++ R V  E+ ++F
Sbjct: 852 ASAAIIVYDVNIADTFSRALAWVKELRQQNTESVLIILAGNKVDLATQHRAVSFEDAQSF 673

Query: 138 AREHGLIFMETSAKTACNVEEAYINTAKEIYRK 170
           ARE+GL+F E SAKT   V E ++  A ++ ++
Sbjct: 672 ARENGLLFAEVSAKTGMAVNEIFMTLANQLIQQ 574
>34597
          Length = 773

 Score = 71.2 bits (173), Expect(2) = 7e-14,   Method: Compositional matrix adjust.
 Identities = 32/80 (40%), Positives = 53/80 (66%)
 Frame = -2

Query: 91  RETFNHLTSWLEDARQHSSSNMVIMLIGNKSDLESRRDVKREEGEAFAREHGLIFMETSA 150
           +++F ++  WL +  +H++ ++  M++GNK D+  +R V +E GEA AREH + FMETSA
Sbjct: 715 KKSFENIVKWLRNIDEHANEDVEKMILGNKCDMTDKRVVSKERGEAIAREHSIRFMETSA 536

Query: 151 KTACNVEEAYINTAKEIYRK 170
           K+  N+E A+   A+ I  K
Sbjct: 535 KSNINIERAFCELAEAILDK 476

 Score = 22.3 bits (46), Expect(2) = 7e-14,   Method: Compositional matrix adjust.
 Identities = 9/12 (75%), Positives = 10/12 (83%)
 Frame = -3

Query: 74  SYYRGAAGALLV 85
           SYYRGA G +LV
Sbjct: 768 SYYRGAMGIMLV 733
>12339
          Length = 578

 Score = 72.4 bits (176), Expect = 1e-13,   Method: Compositional matrix adjust.
 Identities = 42/106 (39%), Positives = 64/106 (60%), Gaps = 5/106 (4%)
 Frame = -2

Query: 65  QESFRSITRSYYRGAAGALLVYDITRRETFNHLTSW----LEDARQHSSSNMVIMLIGNK 120
           QE F+S+  ++YRGA   +LVYD+T  +TF+ L SW    L  A      +   ++IGNK
Sbjct: 577 QERFQSLGVAFYRGADCCILVYDVTEXKTFDSLDSWQREFLNQASPRDPEHFPFVVIGNK 398

Query: 121 SDLESRRDVKREEGEAF-AREHGLIFMETSAKTACNVEEAYINTAK 165
            DL++R  V  + G+ + + + G+ + ETSAK A NVE+A+   AK
Sbjct: 397 IDLDNRV-VTAKRGQGWCSTKGGIPYFETSAKEAINVEQAFQTVAK 263
>26536
          Length = 829

 Score = 71.2 bits (173), Expect = 3e-13,   Method: Compositional matrix adjust.
 Identities = 42/120 (35%), Positives = 62/120 (51%), Gaps = 3/120 (2%)
 Frame = +2

Query: 53  KQIKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRETFNHLTS---WLEDARQHSS 109
           +++     DTAGQE + S+   Y R   G ++VY +T   +F    +   WL   R    
Sbjct: 122 RRVSWTFLDTAGQEEYSSMREHYTRSGDGFIVVYSVTDVTSFQEAEAVFRWL--TRFQDE 295

Query: 110 SNMVIMLIGNKSDLESRRDVKREEGEAFAREHGLIFMETSAKTACNVEEAYINTAKEIYR 169
           +++  +L GNK+DL S R V  EEG   A   G+++ ETSAKT  NV + Y    + I R
Sbjct: 296 TSIHAVLCGNKTDLTSDRKVTPEEGRKMADRLGMLYFETSAKTGDNVSQVYHGLLRSIPR 475
>35581
          Length = 364

 Score = 70.1 bits (170), Expect = 7e-13,   Method: Compositional matrix adjust.
 Identities = 38/100 (38%), Positives = 53/100 (53%), Gaps = 2/100 (2%)
 Frame = +2

Query: 7   FKYIIIGDTGVGKSCLLLQFTDKRF--QPVHDLTIGVEFGARMVNIDGKQIKLQIWDTAG 64
           FK +++GD GVGK+CLL +    +F   P+  LT        +    G    + +WDTAG
Sbjct: 47  FKCVLLGDAGVGKTCLLNRLATDKFLDSPLTSLTTA-SLLTTVTLTSGVMASVDLWDTAG 223

Query: 65  QESFRSITRSYYRGAAGALLVYDITRRETFNHLTSWLEDA 104
           QE +RS+T SYYR     L+VYD   +     LT W + A
Sbjct: 224 QERYRSLTSSYYRDTKAVLIVYDAEHKL---KLTDWTDRA 334
>14119
          Length = 602

 Score = 68.9 bits (167), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 32/83 (38%), Positives = 54/83 (65%), Gaps = 1/83 (1%)
 Frame = +1

Query: 93  TFNHLTSWLEDARQHSSSNMVIMLIGNKSDLESR-RDVKREEGEAFAREHGLIFMETSAK 151
           TFN   +W+++ RQ ++ +++I+L GNK+DL S  R V  ++   FA ++GLIF E SAK
Sbjct: 1   TFNRALAWVKELRQQNAGSVLIVLAGNKADLASEHRAVSADDARTFAEDNGLIFAEVSAK 180

Query: 152 TACNVEEAYINTAKEIYRKIQQG 174
           T   V E ++  A ++ R+ ++G
Sbjct: 181 TGMAVSEVFMTIAHKLVRRAEEG 249
>11728
          Length = 635

 Score = 68.9 bits (167), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 44/159 (27%), Positives = 74/159 (46%), Gaps = 13/159 (8%)
 Frame = -1

Query: 7   FKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMVNIDGKQIKLQIWDTAGQE 66
            K +++GD  VGK+CLL+ +T   F   +  T+   + A  V +D K I L +WDTAGQE
Sbjct: 488 IKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSAN-VMVDSKPINLGLWDTAGQE 312

Query: 67  SFRSITRSYYRGAAGALLVYDITRRETFNHLTSWLEDARQHSSSNMVIMLIGNKSDLESR 126
            +  +    Y      L+ + +    +F ++ +       H   N  I+L+G K DL   
Sbjct: 311 DYDRLRPLSYPQTDVFLICFSLISPASFENVKAKWYPEVSHHCPNTPIILVGTKLDLRED 132

Query: 127 RD------------VKREEGEAFAREHGL-IFMETSAKT 152
           ++            +   +G A A++ G   ++E SA T
Sbjct: 131 KETIEKLKEKKLAPITYPQGLAMAKDIGAGKYLECSALT 15
>27191
          Length = 443

 Score = 68.2 bits (165), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 24/102 (23%), Positives = 59/102 (57%)
 Frame = +1

Query: 19  KSCLLLQFTDKRFQPVHDLTIGVEFGARMVNIDGKQIKLQIWDTAGQESFRSITRSYYRG 78
           K+CL+  F + +F   +  T+GV++G ++  ++G  +++ +WD +G   +  +    Y G
Sbjct: 1   KTCLIKHFCESKFNQGYQPTVGVDYGFKIQTVNGVDMRVHMWDLSGSNEYLDVRNELYTG 180

Query: 79  AAGALLVYDITRRETFNHLTSWLEDARQHSSSNMVIMLIGNK 120
           +    +V+D++   +F  L SWL +  + ++ + + +++GN+
Sbjct: 181 SDAIFIVFDVSNTPSFEALDSWLREINRFATGSPLNVIVGNR 306
>00858
          Length = 1658

 Score = 66.6 bits (161), Expect = 7e-12,   Method: Compositional matrix adjust.
 Identities = 47/150 (31%), Positives = 78/150 (52%), Gaps = 1/150 (0%)
 Frame = -2

Query: 19   KSCLLLQFTDKRFQPVHDLTIGVEFGARMVNIDGKQIKLQIWDTAGQESFRSITRSYYRG 78
            KS L +Q     F   +D T   +   + V IDG+   L I DTAGQE   ++     R 
Sbjct: 1552 KSALTIQLXQNHFVEEYDPTXE-DSXRKQVVIDGETCLLDILDTAGQEEXSAMRDQCMRT 1376

Query: 79   AAGALLVYDITRRETFNHLTSWLEDARQHSSSNMVIM-LIGNKSDLESRRDVKREEGEAF 137
              G L V+ +   ++F  +  + E  ++   ++ V M L+GNK DL   R+V++ +G+  
Sbjct: 1375 GEGFLCVFAVXNLKSFEDINQYREQIKRVKDADEVPMVLVGNKVDLPI-RNVEQRQGKHM 1199

Query: 138  AREHGLIFMETSAKTACNVEEAYINTAKEI 167
            A  + + ++ETSAKT   V++A+    +EI
Sbjct: 1198 AELYHIPYVETSAKTRQGVDDAFYTLVREI 1109
>13745
          Length = 1045

 Score = 65.9 bits (159), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 36/105 (34%), Positives = 59/105 (56%), Gaps = 4/105 (3%)
 Frame = +2

Query: 65  QESFRSITRSYYRGAAGALLVYDITRRETFNHLTSWLED----ARQHSSSNMVIMLIGNK 120
           QE F+S+  ++YRGA   +LVYD+T   +F +L SW ++    A      +   +++GNK
Sbjct: 2   QERFQSLGVAFYRGADCCVLVYDVTAPNSFKNLDSWRDEFLIQASPRDPEHFPFVVLGNK 181

Query: 121 SDLESRRDVKREEGEAFAREHGLIFMETSAKTACNVEEAYINTAK 165
            DL++R+   R   +    ++ + + ETSAK   NVE A+   AK
Sbjct: 182 VDLDNRQVSTRRAQQWCQSKNDIPYYETSAKEGINVEMAFQTIAK 316
>34359
          Length = 1042

 Score = 62.0 bits (149), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 30/90 (33%), Positives = 49/90 (54%)
 Frame = +3

Query: 38  TIGVEFGARMVNIDGKQIKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRETFNHL 97
           T+GVE      N     ++  +WDTAGQE F  +   YY     A++++D+T R T+ ++
Sbjct: 144 TLGVEVHPLQFNTSRGLLRFNVWDTAGQEKFGGLRDGYYIQGTCAIIMFDVTSRVTYKNV 323

Query: 98  TSWLEDARQHSSSNMVIMLIGNKSDLESRR 127
            +W  D       N+ I+L GNK D++ R+
Sbjct: 324 PNWHRDL-VRVCENIPIVLCGNKVDIKDRK 410
>19656
          Length = 428

 Score = 60.5 bits (145), Expect = 5e-10,   Method: Compositional matrix adjust.
 Identities = 29/101 (28%), Positives = 53/101 (52%), Gaps = 1/101 (0%)
 Frame = +3

Query: 8   KYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMVNIDGKQIKLQIWDTAGQES 67
           K +++GD  VGK+CLL+ +T   F   +  T+   + A ++ +DG+ + L +WDTAGQE 
Sbjct: 117 KCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVM-VDGRPVNLGLWDTAGQED 293

Query: 68  FRSITRSYYRGAAGALLVYDITRRETFNHLTS-WLEDARQH 107
           +  +    Y      LL + +    +F ++ + W  +   H
Sbjct: 294 YDRLRPLSYPQTDVFLLCFSVASPASFENIRAKWYPEVNHH 416
>25618
          Length = 475

 Score = 57.4 bits (137), Expect = 5e-09,   Method: Compositional matrix adjust.
 Identities = 28/71 (39%), Positives = 46/71 (64%), Gaps = 1/71 (1%)
 Frame = +3

Query: 105 RQHSSSNMVIMLIGNKSDLESR-RDVKREEGEAFAREHGLIFMETSAKTACNVEEAYINT 163
           RQ ++ +++I+L GNK+DL S  R V  ++   FA ++GLIF E SAKT   V E ++  
Sbjct: 57  RQQNAGSVLIVLAGNKADLASEHRAVSADDARTFAEDNGLIFAEVSAKTGMAVSEVFMTI 236

Query: 164 AKEIYRKIQQG 174
           A ++ R+ ++G
Sbjct: 237 AHKLVRRAEEG 269
>09204
          Length = 1051

 Score = 56.2 bits (134), Expect = 9e-09,   Method: Compositional matrix adjust.
 Identities = 32/103 (31%), Positives = 55/103 (53%), Gaps = 4/103 (3%)
 Frame = -3

Query: 68   FRSITRSYYRGAAGALLVYDITRRETFNHLTSWLEDARQHSSSNMVIMLIGNKSDL---- 123
            + +++R YYRGA  A+L +D+T + +F+ +  W+ + RQH      + + G K DL    
Sbjct: 1046 YEAMSRIYYRGAKAAILCFDLTDKSSFDRIRFWIGELRQH-EEECKLYICGTKFDLVHDD 870

Query: 124  ESRRDVKREEGEAFAREHGLIFMETSAKTACNVEEAYINTAKE 166
              RR V R   +A A +      ETS+ T  N+E+ +   A++
Sbjct: 869  PERRAVPRSVAKALADDCMAEIYETSSMTGDNIEKLFTKIAED 741
>14775
          Length = 380

 Score = 52.8 bits (125), Expect = 9e-08,   Method: Compositional matrix adjust.
 Identities = 43/149 (28%), Positives = 60/149 (40%), Gaps = 3/149 (2%)
 Frame = -2

Query: 19  KSCLLLQFTDKRFQPVHDLTIGV---EFGARMVNIDGKQIKLQIWDTAGQESFRSITRSY 75
           K+CLL ++    F      TI V   EF       D   ++  +WDT G E++RS+  S+
Sbjct: 379 KTCLLRRYQKGFFMDRTMPTIAVLCSEFNES--RTDPLNVRYTLWDTGGAETYRSLWVSH 206

Query: 76  YRGAAGALLVYDITRRETFNHLTSWLEDARQHSSSNMVIMLIGNKSDLESRRDVKREEGE 135
           +RGA  ALLVYD+T                                          E G+
Sbjct: 205 FRGAQVALLVYDVT-----------------------------------------CERGQ 149

Query: 136 AFAREHGLIFMETSAKTACNVEEAYINTA 164
           AFA + G  F ETS+ T  NV+  +   A
Sbjct: 148 AFATQCGYTFFETSSVTGKNVDAVFWEIA 62
>10708
          Length = 2775

 Score = 36.2 bits (82), Expect(2) = 2e-06,   Method: Compositional matrix adjust.
 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 13/77 (16%)
 Frame = -3

Query: 97   LTSWLEDARQHSSSNMVIMLIGNKSDLESRRDVKRE------------EGEAFARE-HGL 143
            L  W  + R H   N+ I+L+GNK DL +  + KRE            EG A + + +  
Sbjct: 2593 LKKWTPEVR-HFCPNVPIILVGNKKDLRNDENTKRELMKMKQEPVRLDEGRAMSEKINAY 2417

Query: 144  IFMETSAKTACNVEEAY 160
             ++E SAKT   V E +
Sbjct: 2416 SYLECSAKTKEGVREVF 2366

 Score = 31.6 bits (70), Expect(2) = 2e-06,   Method: Compositional matrix adjust.
 Identities = 12/45 (26%), Positives = 24/45 (53%)
 Frame = -2

Query: 53   KQIKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRETFNHL 97
            +Q++L +WDTAGQE +  +    Y      L+ + I   ++  ++
Sbjct: 2729 QQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENI 2595
>08153
          Length = 1703

 Score = 45.1 bits (105), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 29/119 (24%), Positives = 52/119 (43%), Gaps = 3/119 (2%)
 Frame = +1

Query: 8   KYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMVNIDGKQIKLQIWDTAGQES 67
           + +++G    GK+ +L +           +T     G  +  ++ K I   +WD  GQ+ 
Sbjct: 88  RILMVGLDAAGKTTILYKLKLGEI-----VTTIPTIGFNVETVEYKNISFTVWDVGGQDK 252

Query: 68  FRSITRSYYRGAAGALLVYDITRRETFNHLTSWLEDARQHSSSNM---VIMLIGNKSDL 123
            R + R Y++   G + V D   RE  N      E AR  +  ++   +I++  NK DL
Sbjct: 253 IRPLWRHYFQNTQGLIFVVDSNDRERINEAKE--ELARMLNEDDLRDAIILVFANKQDL 423
>00552
          Length = 455

 Score = 43.9 bits (102), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 22/53 (41%), Positives = 32/53 (60%)
 Frame = -1

Query: 6   LFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMVNIDGKQIKLQ 58
           L K +++GD GVGKS L+ +F   +F      TIGVEF  + V +DG+   +Q
Sbjct: 446 LLKVVLLGDGGVGKSSLMNRFVSNKFDAQSFHTIGVEFLTKDVVVDGETFTMQ 288

 Score = 42.0 bits (97), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 16/45 (35%), Positives = 27/45 (60%)
 Frame = -3

Query: 59  IWDTAGQESFRSITRSYYRGAAGALLVYDITRRETFNHLTSWLED 103
           IWDTAGQE ++S+   +YRG    LL + +   ++   L+ W ++
Sbjct: 147 IWDTAGQERYKSLRTPFYRGTDCCLLTFSVDNLKSLQSLSDWYDE 13
>33605
          Length = 888

 Score = 42.4 bits (98), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 23/84 (27%), Positives = 40/84 (47%)
 Frame = +1

Query: 8   KYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMVNIDGKQIKLQIWDTAGQES 67
           + +++G    GK+ +L +F  +        TI    G  +  ++ +  KL +WD  GQ+S
Sbjct: 502 RLLMLGLDNAGKTTILKKFNGEDID-----TISPTLGFNIKTLEHRGFKLNVWDVGGQQS 666

Query: 68  FRSITRSYYRGAAGALLVYDITRR 91
            RS  R+Y+    G + V D   R
Sbjct: 667 LRSYWRNYFESTDGLVWVVDSADR 738
>31291
          Length = 446

 Score = 42.4 bits (98), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 33/123 (26%), Positives = 56/123 (45%), Gaps = 14/123 (11%)
 Frame = -1

Query: 57  LQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRETFNHL-TSWLEDARQHSSSNMVIM 115
           LQ+WDTAGQE +  +    Y      +L + +    +  ++   W  + R H   ++ I+
Sbjct: 446 LQLWDTAGQEDYDRLRPLAYPNTDVFMLXFSLMSEASMKNVKVKWYPEIRHH-DPHVPIV 270

Query: 116 LIGNKSDLE-----------SRRD-VKREEGEAFARE-HGLIFMETSAKTACNVEEAYIN 162
           L+G K DL            SR+D V   +G   A+      + E S+KT  N++ A+  
Sbjct: 269 LVGTKLDLRQDKEAVRKLRSSRQDPVSSNQGNDLAKAIKAKRYFECSSKTQENLKTAFEE 90

Query: 163 TAK 165
           T +
Sbjct: 89  TVR 81
>10862
          Length = 2896

 Score = 41.6 bits (96), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 22/83 (26%), Positives = 37/83 (44%), Gaps = 8/83 (9%)
 Frame = -3

Query: 49   NIDGKQIKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRETFNHLTSWLEDARQ-- 106
            N   ++ +  +WD  GQ+  R + R YY G  G + V D   R+        +++ARQ  
Sbjct: 2504 NCQLQECQFNVWDVGGQDKIRPLWRHYYTGTQGLIFVVDCADRDR-------IDEARQEL 2346

Query: 107  ------HSSSNMVIMLIGNKSDL 123
                      + +I++  NK DL
Sbjct: 2345 HRIINDREMRDAIILIFANKQDL 2277
>25796
          Length = 422

 Score = 40.4 bits (93), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 17/25 (68%), Positives = 19/25 (76%)
 Frame = -1

Query: 2  TYAYLFKYIIIGDTGVGKSCLLLQF 26
          TY YLFK++IIG  G GKSCLL  F
Sbjct: 80 TYDYLFKFLIIGSAGSGKSCLLHHF 6
>18509
          Length = 625

 Score = 40.0 bits (92), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 22/65 (33%), Positives = 40/65 (61%)
 Frame = -3

Query: 103 DARQHSSSNMVIMLIGNKSDLESRRDVKREEGEAFAREHGLIFMETSAKTACNVEEAYIN 162
           D R   +  + ++L+GNK DL  R +V++ +G+  A  + + ++ETSAKT   V++A+  
Sbjct: 554 D*RVKDADEVPMVLVGNKVDLPIR-NVEQRQGKHMAELYHIPYVETSAKTRQGVDDAFYT 378

Query: 163 TAKEI 167
             +EI
Sbjct: 377 LVREI 363
>09827
          Length = 1201

 Score = 38.5 bits (88), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 27/121 (22%), Positives = 51/121 (42%), Gaps = 4/121 (3%)
 Frame = -3

Query: 7    FKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMVNIDGKQIKLQIWDTAGQE 66
             + +++G    GK+ +L      + +    +T     G  +  ++ K I   +WD  GQ+
Sbjct: 1112 MRILMVGLDAAGKTTILY-----KLKLGEIVTTIPTIGFNVETVEYKNISFTVWDVGGQD 948

Query: 67   SFRSITRSYYRGAAGALLVYDITRRETFN----HLTSWLEDARQHSSSNMVIMLIGNKSD 122
              R + R Y++   G + V D   +E        LT  L +     +   V+++  NK D
Sbjct: 947  KIRPLWRHYFQNTQGLIFVVDSNDKERVQEAREELTRMLNEDELRDA---VLLVFANKQD 777

Query: 123  L 123
            L
Sbjct: 776  L 774
>31932
          Length = 437

 Score = 35.0 bits (79), Expect = 0.020,   Method: Compositional matrix adjust.
 Identities = 25/89 (28%), Positives = 44/89 (49%), Gaps = 3/89 (3%)
 Frame = -1

Query: 100 WLEDARQHSSSNMVIMLIGNKSDLESRRDVKREEGEAFAREHGLI-FMETSAKTACNVEE 158
           W         S +  +L+GNKSDL   R+V+++E E   +EH  + + ETS K    ++E
Sbjct: 437 WTASVNWPYGSTVPCLLLGNKSDL-GHREVEQDEIEDLCKEHDFLGWSETSVKDGTMIDE 261

Query: 159 AYINTAKEIYRKIQ--QGLFDVHNEANGI 185
           +     +E+  K    +G  +   + NG+
Sbjct: 260 SMNYLIEEMMAKHAELEGFSESVTQGNGV 174
>25727
          Length = 426

 Score = 29.6 bits (65), Expect = 1.0,   Method: Compositional matrix adjust.
 Identities = 28/102 (27%), Positives = 42/102 (41%)
 Frame = +1

Query: 107 HSSSNMVIMLIGNKSDLESRRDVKREEGEAFAREHGLIFMETSAKTACNVEEAYINTAKE 166
           H     V+   G  +D  + +    EE   F   H      + ++T C        TAKE
Sbjct: 52  HPPDRNVVGKDGPTADQTNEKCYDSEEWTTFKTLHSSPQTTSGSRTHC--------TAKE 207

Query: 167 IYRKIQQGLFDVHNEANGIKIGPQQSITSSVGPCSPQQNVSD 208
              + +  +    N+ NG     +  +T+SV PCSP Q VSD
Sbjct: 208 ---QCEHDVLHTQNKYNGSGKFRENIVTNSV-PCSPNQLVSD 321
>33890
          Length = 220

 Score = 28.9 bits (63), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 15/37 (40%), Positives = 20/37 (54%)
 Frame = +3

Query: 70  SITRSYYRGAAGALLVYDITRRETFNHLTSWLEDARQ 106
           S+ RS   G    L +YD+T  ET+ HL+  LE   Q
Sbjct: 75  SVVRSKPNGCFLCLSIYDVTAFETW*HLSVKLEKVSQ 185
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31543605|ref|NP_598694.2| ribophorin I [Mus musculus]
         (608 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

17306                                                                 154   1e-37
11970                                                                  33   0.45 
17530                                                                  30   3.4  
07982                                                                  30   4.2  
>17306
          Length = 552

 Score =  154 bits (389), Expect = 1e-37,   Method: Compositional matrix adjust.
 Identities = 73/147 (49%), Positives = 99/147 (67%), Gaps = 2/147 (1%)
 Frame = -2

Query: 334 GYNLPSYEYLYNLGDQYALKMRFVDHVFDEQVIDSLTVKIILPEGAKNIQVDSPYDISRA 393
           GYN+PSYEYL++ G+ Y LKM  +DH+ D   ID   V +ILPEG+ NI++ +P+ I R 
Sbjct: 551 GYNVPSYEYLFSSGNDYVLKMHLIDHIHDNMAIDEAIVTVILPEGSSNIELITPFSIKRH 372

Query: 394 PDELHYTYLDTFGRPVIVAYKKNLVEQHIQDIVVHYTFNKVLMLQEPLLVVAAFYILFFT 453
            +EL +TYLDT GRPV+   K NLVE HI +  + YTF+KV +LQEPLLV+   Y++F  
Sbjct: 371 QNELIHTYLDTVGRPVVSFSKTNLVENHISEFTLKYTFSKVSLLQEPLLVIGFIYMIFIF 192

Query: 454 VIIYVRLDFSITKDPAA--EARMKVAC 478
            I+ +RLDFSIT  P    +  + V C
Sbjct: 191 TIVLLRLDFSITSHPHKD*DGILSVFC 111
>11970
          Length = 922

 Score = 32.7 bits (73), Expect = 0.45,   Method: Compositional matrix adjust.
 Identities = 18/46 (39%), Positives = 29/46 (63%), Gaps = 1/46 (2%)
 Frame = +1

Query: 249 VDLKHTGAV-LKGPFSRYDYQRQPDSGISSIRSFKTILPAAAQDVY 293
           V +++T  V L  P SR   QR   SG++ + +  T+LP++AQ+VY
Sbjct: 634 VAIQYTKCVSLTHPTSRTTRQRVTWSGVNPVATTVTVLPSSAQNVY 771
>17530
          Length = 503

 Score = 29.6 bits (65), Expect = 3.4,   Method: Composition-based stats.
 Identities = 18/37 (48%), Positives = 24/37 (64%)
 Frame = -3

Query: 30  PPLVNEDVKRTVDLSSHLAKVTAEVVLVHPGGGSTSR 66
           PPL +E VKRT   SS+ + V +EV+L  PGG  T +
Sbjct: 144 PPL-DEQVKRTR*PSSNTSPVMSEVMLGGPGGSRTVK 37
>07982
          Length = 901

 Score = 29.6 bits (65), Expect = 4.2,   Method: Compositional matrix adjust.
 Identities = 22/67 (32%), Positives = 31/67 (46%), Gaps = 9/67 (13%)
 Frame = -3

Query: 354 MRFVDHVFDEQVIDSLTVKIILP---------EGAKNIQVDSPYDISRAPDELHYTYLDT 404
            ++V+    ++V DS TV  ILP         E A+NI   + Y     PD  HY + D 
Sbjct: 368 WQYVNRSLVDKVPDSGTVTAILPQQGKEAEVLEQARNIPHVTAYRKENIPDHFHYKHNDR 189

Query: 405 FGRPVIV 411
              PVI+
Sbjct: 188 I-MPVII 171
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|50233838|ref|NP_001001983.1| phosphatidylinositol
4-kinase type 3 alpha [Mus musculus]
         (2044 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

06655                                                                 155   1e-37
25710                                                                 131   2e-30
18761                                                                  70   1e-11
34349                                                                  52   2e-06
15038                                                                  35   0.28 
05263                                                                  32   2.0  
26068                                                                  31   4.7  
15794                                                                  31   6.3  
>06655
          Length = 1350

 Score =  155 bits (393), Expect = 1e-37,   Method: Compositional matrix adjust.
 Identities = 82/190 (43%), Positives = 124/190 (65%), Gaps = 5/190 (2%)
 Frame = -2

Query: 1858 MYDYFTRQYGDESTLAFQQARYNFIRSMAAYSLLLFLLQIKDRHNGNIMLDKKGHIIHID 1917
            + DYF  ++G  ++  F  A+ NF++S A Y L+ +L+Q+KDRHNGNI+LD +GHIIHID
Sbjct: 1328 LLDYFVHEFGPSNSEEFLTAQKNFVQSCAGYCLVCYLMQVKDRHNGNILLDAEGHIIHID 1149

Query: 1918 FGFMFESSPGGNLGWEPD-IKLTDEMVMIMGGKMEATPFKWFMEMCVRGYLAVRPYMDAV 1976
            FGF+  +SPG NLG+E    KLT E V +MGG+  +  F++F  + ++G++A R +MD +
Sbjct: 1148 FGFILSTSPGKNLGFENSPFKLTTEFVEVMGGQ-GSDMFEYFKILMLQGFVASRKHMDQI 972

Query: 1977 VSLVTLMLDTG--LPCF-RG-QTIKLLKHRFSPNMTEREAANFIMKVIQNCFLSNRSRTY 2032
            + LV +M  TG  LPCF +G  T++ LK RF  NMTE +    +  ++++   S  ++ Y
Sbjct: 971  LPLVEIM-QTGSQLPCFSKGVSTVRGLKDRFHMNMTEEQLQLLVDNLVESSLHSLTTKLY 795

Query: 2033 DMIQYYQNDI 2042
            D  QY  N I
Sbjct: 794  DGFQYLTNGI 765
>25710
          Length = 429

 Score =  131 bits (330), Expect = 2e-30,   Method: Compositional matrix adjust.
 Identities = 57/140 (40%), Positives = 89/140 (63%)
 Frame = -3

Query: 1136 FKLTAMLISSKDCDPQLLHHLCWGPLRMFNEHGMETALACWEWLLAGKNGVEVPFMREMA 1195
            F++ A+ I  +    +LLH +CW P+  F+E  M  ++ACW+W+LA +  + + F+ EMA
Sbjct: 427  FRICALQIKLESISRRLLHAVCWAPVHYFSEAVMAMSVACWDWILAARPDISMEFLCEMA 248

Query: 1196 GAWHMTVEQKFGLFSVETKEADPLAASEASQPRPCPPEVTPHYIWIDFLVQRFEIAKYCS 1255
             AW M V+++ G+F+ +   +DPLA  E     P PP V PH  W  FL++R EIAKY S
Sbjct: 247  AAWQMCVDRRLGIFAEDAPRSDPLAKKENEVLAPNPPYVGPHQAWTKFLLERVEIAKYSS 68

Query: 1256 SDQVEIFSSLLQRSMSLNIG 1275
            + QVE+   LL +S+S+++G
Sbjct: 67   ASQVEVLMCLLNKSLSISVG 8
>18761
          Length = 492

 Score = 70.1 bits (170), Expect = 1e-11,   Method: Composition-based stats.
 Identities = 42/135 (31%), Positives = 75/135 (55%), Gaps = 5/135 (3%)
 Frame = +3

Query: 1897 IKDRHNGNIMLDKKGHIIHIDFG-FMFESSPGGNLGWE--PDIKLTDEMVMIM--GGKME 1951
            I DRHN NIML + GH+ HIDF  F+ ++   GN+  +  P + LT +MV ++  GGK +
Sbjct: 3    IGDRHNDNIMLKQSGHMFHIDFSKFLGDAQMFGNIKRDRVPFV-LTPDMVFVINDGGK-Q 176

Query: 1952 ATPFKWFMEMCVRGYLAVRPYMDAVVSLVTLMLDTGLPCFRGQTIKLLKHRFSPNMTERE 2011
               F+ F+++C + +  +R + D   +L  LM  +G+P    Q +  ++    P  T+ +
Sbjct: 177  GNRFQQFIDLCCQAFNILRTHADLFRNLFMLMSRSGIPGVTEQAVTYIQRALLPGYTKAQ 356

Query: 2012 AANFIMKVIQNCFLS 2026
            A+    ++I++   S
Sbjct: 357  ASAAFTRMIEDSMRS 401
>34349
          Length = 413

 Score = 52.0 bits (123), Expect = 2e-06,   Method: Composition-based stats.
 Identities = 30/93 (32%), Positives = 51/93 (54%)
 Frame = +2

Query: 1897 IKDRHNGNIMLDKKGHIIHIDFGFMFESSPGGNLGWEPDIKLTDEMVMIMGGKMEATPFK 1956
            + DRH  N++L   G + HIDFG++    P         +KL+ EMV  MGG + +  + 
Sbjct: 5    VGDRHLDNLLLTTNGKLFHIDFGYILGRDPKPMPP---PMKLSKEMVEAMGG-VSSDHYH 172

Query: 1957 WFMEMCVRGYLAVRPYMDAVVSLVTLMLDTGLP 1989
             F + C   YL +R + + +++L +LM+D  +P
Sbjct: 173  EFRKQCYTAYLHLRRHANVMLNLFSLMVDASVP 271
>15038
          Length = 695

 Score = 35.0 bits (79), Expect = 0.28,   Method: Composition-based stats.
 Identities = 25/67 (37%), Positives = 31/67 (46%), Gaps = 1/67 (1%)
 Frame = +1

Query: 1214 KEADPLAASEASQPRPCPPEVTPHYIWIDFLVQRFEIAKY-CSSDQVEIFSSLLQRSMSL 1272
            K AD   A +  Q  P  P V PH  W    VQR E +     ++ VE+FS   QRS  +
Sbjct: 67   KPADKAEAGQEDQAEPTNPTVGPHEDWQHH*VQRKEASLA*DQAEDVEVFSH--QRSCLV 240

Query: 1273 NIGGARG 1279
                ARG
Sbjct: 241  RFSQARG 261
>05263
          Length = 554

 Score = 32.3 bits (72), Expect = 2.0,   Method: Compositional matrix adjust.
 Identities = 17/56 (30%), Positives = 32/56 (57%)
 Frame = +1

Query: 1649 DIGDLLEQLVEEITGSLSGPAKDFYQREFDFFNKITNVSAIIKPYPKGDERKKACL 1704
            +I   ++  ++ I  S S P K+  +++ +FFNK+ +  A+ K     D++ KACL
Sbjct: 190  NIPPNMDNSIQSINPSFSSPLKNNNKKQSNFFNKLISSKAV*K-TTDNDKKYKACL 354
>26068
          Length = 460

 Score = 31.2 bits (69), Expect = 4.7,   Method: Composition-based stats.
 Identities = 14/39 (35%), Positives = 24/39 (61%), Gaps = 1/39 (2%)
 Frame = +2

Query: 1893 FLLQIKDRHNGNIMLD-KKGHIIHIDFGFMFESSPGGNL 1930
            +++ + DRH  N+++D   G ++HID+   FE   G NL
Sbjct: 11   YIIGLGDRHLDNVLVDLATGEVVHIDYNVCFEK--GKNL 121
>15794
          Length = 929

 Score = 30.8 bits (68), Expect = 6.3,   Method: Composition-based stats.
 Identities = 17/44 (38%), Positives = 25/44 (56%), Gaps = 2/44 (4%)
 Frame = -3

Query: 1393 GWINTYPLSSG--MSTISKKSGMSKKTNRGSQLHKYYMKRRTLL 1434
             W  +Y LS+G  M  + ++S +S  T+  SQLH Y+ K  T L
Sbjct: 600  AWNVSYTLSAGKCMQQLDEQSXVSIVTDHTSQLHGYHRKLNTCL 469
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6678794|ref|NP_032953.1| mitogen-activated protein
kinase kinase 1 [Mus musculus]
         (393 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

18921                                                                 153   1e-37
19094                                                                  93   3e-29
01707                                                                 109   2e-24
12721                                                                 105   4e-23
13592                                                                 100   9e-22
13840                                                                 100   2e-21
00300                                                                  95   5e-20
01718                                                                  94   1e-19
14420                                                                  92   3e-19
13212                                                                  91   1e-18
09606                                                                  88   6e-18
01060                                                                  86   4e-17
21210                                                                  84   1e-16
21808                                                                  79   2e-15
31885                                                                  79   3e-15
00392                                                                  77   1e-14
06405                                                                  77   1e-14
03240                                                                  76   2e-14
18484                                                                  71   7e-13
14126                                                                  69   3e-12
01756                                                                  69   3e-12
19301                                                                  67   1e-11
13066                                                                  67   2e-11
27405                                                                  65   5e-11
19761                                                                  65   7e-11
37602                                                                  60   9e-11
07291                                                                  64   1e-10
28638                                                                  64   1e-10
30755                                                                  63   2e-10
28157                                                                  59   4e-09
26560                                                                  58   5e-09
29581                                                                  58   6e-09
09007                                                                  57   1e-08
11185                                                                  57   1e-08
00715                                                                  57   2e-08
04852                                                                  56   2e-08
04591                                                                  56   3e-08
21433                                                                  56   3e-08
17975                                                                  56   3e-08
27546                                                                  56   3e-08
14477                                                                  55   4e-08
15910                                                                  54   1e-07
12786                                                                  54   1e-07
01966                                                                  53   2e-07
07940                                                                  52   4e-07
04138                                                                  52   5e-07
21079                                                                  49   4e-06
14116                                                                  49   4e-06
01392                                                                  49   5e-06
32691                                                                  48   6e-06
17253                                                                  48   8e-06
03508                                                                  47   1e-05
25019                                                                  47   1e-05
07836                                                                  47   1e-05
12672                                                                  46   2e-05
18996                                                                  46   3e-05
26711                                                                  45   5e-05
18663                                                                  45   7e-05
17300                                                                  43   3e-04
02638                                                                  42   4e-04
11780                                                                  42   4e-04
26156                                                                  42   4e-04
17637                                                                  41   7e-04
20640                                                                  38   0.007
32000                                                                  37   0.011
00486                                                                  35   0.038
32957                                                                  35   0.040
20559                                                                  35   0.055
01106                                                                  35   0.060
38560                                                                  35   0.061
21800                                                                  34   0.085
16708                                                                  34   0.089
13305                                                                  34   0.10 
29590                                                                  33   0.22 
18401                                                                  32   0.48 
31489                                                                  30   1.8  
15549                                                                  30   2.0  
22501                                                                  29   3.1  
22098                                                                  29   3.2  
22005                                                                  29   3.4  
>18921
          Length = 697

 Score =  153 bits (386), Expect = 1e-37,   Method: Compositional matrix adjust.
 Identities = 77/202 (38%), Positives = 130/202 (64%), Gaps = 3/202 (1%)
 Frame = +2

Query: 65  DDDFEKISELGAGNGGVVFKVSHKPSGLVMARKLIHLEIKPAIRNQIIRELQVLHECNSP 124
           +D F+ + +LG G+ G VFK  HK +G V+A K + ++       +II+E+ ++ +C+S 
Sbjct: 26  EDVFDILGKLGEGSYGSVFKSLHKETGQVLAIKQVPVDTD---LQEIIKEISIMQQCDSK 196

Query: 125 YIVGFYGAFYSDGEISICMEHMDGGSLDQVLK-KAGRIPEQILGKVSIAVIKGLTYLREK 183
           YIV +YG+++ + ++ I ME+   GS+  +++ +   + E+ +  +    +KGL YL  +
Sbjct: 197 YIVKYYGSYFKNTDLWIVMEYCGAGSVSDIMRLRNKTLVEREIATILYYTLKGLXYLHSR 376

Query: 184 HKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMA--NSFVGTRSYMSPERLQGTHYS 241
            KI HRD+K  NIL+N+ G  KL DFGV+GQL D+MA  N+ +GT  +M+PE +Q   Y 
Sbjct: 377 RKI-HRDIKAGNILLNNEGHAKLADFGVAGQLTDTMAKRNTVIGTPYWMAPEVIQEIGYD 553

Query: 242 VQSDIWSMGLSLVEMAVGRYPI 263
             +DIWS+G++ +EMA G+ P+
Sbjct: 554 CVADIWSLGITALEMAEGKPPV 619
>19094
          Length = 898

 Score = 93.2 bits (230), Expect(2) = 3e-29,   Method: Compositional matrix adjust.
 Identities = 48/114 (42%), Positives = 74/114 (64%), Gaps = 3/114 (2%)
 Frame = +1

Query: 149 GSLDQVLK-KAGRIPEQILGKVSIAVIKGLTYLREKHKIMHRDVKPSNILVNSRGEIKLC 207
           GS+  +++ +   + E+ +  +    +KGL YL  + KI HRD+K  NIL+N+ G  KL 
Sbjct: 10  GSVSDIMRLRNKTLVEREIATILYYTLKGL*YLHSRRKI-HRDIKAGNILLNNEGHAKLA 186

Query: 208 DFGVSGQLIDSMA--NSFVGTRSYMSPERLQGTHYSVQSDIWSMGLSLVEMAVG 259
           DFGV+GQL D+MA  N+ +GT  +M+PE +Q   Y   +DIWS+G++ +EMA G
Sbjct: 187 DFGVAGQLTDTMAKRNTVIGTPYWMAPEVIQEIGYDCVADIWSLGITALEMAEG 348

 Score = 53.1 bits (126), Expect(2) = 3e-29,   Method: Compositional matrix adjust.
 Identities = 32/71 (45%), Positives = 41/71 (57%), Gaps = 1/71 (1%)
 Frame = +3

Query: 300 YGMDSRPPMAIFELLDYIVNEPPPKLPS-GVFSLEFQDFVNKCLIKNPAERADLKQLMVH 358
           YG D  P  AIF     I  +PPP       +S EF DFV+KCL+KNP  RA    L+ H
Sbjct: 357 YG-DIHPMRAIF----MIPTKPPPSFRQPDKWSTEFIDFVSKCLVKNPENRATAVDLLQH 521

Query: 359 AFIKRSDAEEV 369
            FIK+++A E+
Sbjct: 522 DFIKKAEACEI 554
>01707
          Length = 757

 Score =  109 bits (272), Expect = 2e-24,   Method: Compositional matrix adjust.
 Identities = 64/214 (29%), Positives = 113/214 (52%), Gaps = 5/214 (2%)
 Frame = +1

Query: 66  DDFEKISELGAGNGGVVFKVSHK-PSGLVMARKLIHLEIKPAIRNQIIRELQVLHECNSP 124
           + +EKI ++G G+ GVVFK  +K  S LV  +K +  E  P I+   +RE+++L +   P
Sbjct: 64  EKYEKIGKIGEGSYGVVFKCRNKETSQLVAIKKFVESEDDPLIKKIAMREIRMLKQLKHP 243

Query: 125 YIVGFYGAFYSDGEISICMEHMDGGSLDQVLKKAGRIPEQILGKVSIAVIKGLTYLREKH 184
            +V     F     + +  +++D   L+++ +    +PE ++ ++    +  + +  + +
Sbjct: 244 NLVRLIEVFRRKKRLHLVFDYVDHTLLNELDRYPRGLPEPMVKRIIYQTLLAVNFCHQ-Y 420

Query: 185 KIMHRDVKPSNILVNSRGEIKLCDFGVSGQLI--DSMANSFVGTRSYMSPERLQG-THYS 241
             +HRDVKP NIL+  +G++KLCDFG +  L         +V TR Y +PE L G T Y 
Sbjct: 421 NTIHRDVKPENILITRQGQVKLCDFGFARILTGPGDEYTDYVATRWYRAPELLVGDTQYG 600

Query: 242 VQSDIWSMGLSLVEMAVGRYPIP-PPDAKELELL 274
              D+W++G    E+  G+   P   D  +L L+
Sbjct: 601 PPVDVWAIGCVFAELLTGQALWPGRSDVDQLHLI 702
>12721
          Length = 821

 Score =  105 bits (261), Expect = 4e-23,   Method: Compositional matrix adjust.
 Identities = 82/288 (28%), Positives = 136/288 (47%), Gaps = 3/288 (1%)
 Frame = +1

Query: 66  DDFEKISELGAGNGGVVFKVSHKPSGLVMARKLIHLEIKPAIRNQIIRELQVLHECNSPY 125
           DDF KI   G G+ G+V   + +  G  MA K + L  K   R  +  E+ V+ + + P 
Sbjct: 97  DDFMKI---GEGSTGIVCIATSR-DGRQMAVKKMDLR-KQQRRELLFNEVVVMRDYHHPN 261

Query: 126 IVGFYGAFYSDGEISICMEHMDGGSLDQVLKKAGRIPEQILGKVSIAVIKGLTYLREKHK 185
           IV  Y ++  + E+ + ME M+GG+L  ++    R+ E  +  V  A +K L +L   + 
Sbjct: 262 IVEMYNSYLVNDELWVVMEFMEGGALTDIVTN-NRMDEVQIATVCRACLKALAFL-HANG 435

Query: 186 IMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMAN--SFVGTRSYMSPERLQGTHYSVQ 243
           ++HRD+K  +IL++  G++KL DFG   Q+   +    S VGT  +M+PE +    Y  +
Sbjct: 436 VIHRDIKSDSILLSHDGKVKLXDFGFCAQVTQDLQKRKSLVGTPYWMAPEVISRLPYGPE 615

Query: 244 SDIWSMGLSLVEMAVGRYPIPPPDAKELELLFGCHVEGDAAEXXXXXXXXXXXLSSYGMD 303
            DIWS+G+ ++EM        PP   E                                 
Sbjct: 616 VDIWSLGIMVMEMIDAE----PPFFNE--------------------------------- 684

Query: 304 SRPPMAIFELLDYIVNEPPPKLP-SGVFSLEFQDFVNKCLIKNPAERA 350
             PP+   + +  I + PPPKL  +   S   Q F+++ L+++P +RA
Sbjct: 685 --PPL---QAMRRIRDMPPPKLRNTHKISPRLQGFIDRMLVRDPHQRA 813
>13592
          Length = 980

 Score =  100 bits (249), Expect = 9e-22,   Method: Compositional matrix adjust.
 Identities = 85/311 (27%), Positives = 144/311 (46%), Gaps = 13/311 (4%)
 Frame = +2

Query: 73  ELGAGNGGVVFKVSHKPSGLVMARKLIHLEIKP----AIRNQIIRELQVLHECNSPYIVG 128
           ++G G  G V+   +  +G +MA K I   I+P    A++N +  EL++L       +V 
Sbjct: 5   KIGQGRFGKVYTAVNNNTGELMAMKEI--AIQPGETRALKN-VAEELKILEGIKHKNLVR 175

Query: 129 FYGAFYSDGEISICMEHMDGGSLDQVLKKAGRIPEQILGKVSIAVIKGLTYLREKHKIMH 188
           +YG      E+ I ME    G+L+ +++  G +PE +  + +  ++ G+  L  KH I+H
Sbjct: 176 YYGIEVHREELLIFMELCSEGTLESLVELTGGLPEALSRRFTAQLLSGVAELH-KHGIVH 352

Query: 189 RDVKPSNI-LVNSRGEIKLCDFGVSGQL-----IDSMANSFVGTRSYMSPERLQGTH--- 239
           RD+K +NI LV+    +KL DFG + ++     +      +VGT++YM+PE    T+   
Sbjct: 353 RDIKTANIFLVDGSNSLKLGDFGSAVKIQAHTTVPGELQGYVGTQAYMAPEVFTKTNSDG 532

Query: 240 YSVQSDIWSMGLSLVEMAVGRYPIPPPDAKELELLFGCHVEGDAAEXXXXXXXXXXXLSS 299
           +   +DIWS+G  +VEMA G+ P    D+   +++F                        
Sbjct: 533 HGRLADIWSVGCVVVEMASGKRPWAQFDSN-FQIMF-----------------------K 640

Query: 300 YGMDSRPPMAIFELLDYIVNEPPPKLPSGVFSLEFQDFVNKCLIKNPAERADLKQLMVHA 359
            GM  +P             + P  L     S E  DF++ CL  +P +R    +L+   
Sbjct: 641 VGMGEKP-------------QAPESL-----SQEGHDFIDHCLQHDPKQRLSAIELLEQN 766

Query: 360 FIKRSDAEEVD 370
           F K    EE +
Sbjct: 767 FCKSGRDEECN 799
>13840
          Length = 446

 Score = 99.8 bits (247), Expect = 2e-21,   Method: Compositional matrix adjust.
 Identities = 54/136 (39%), Positives = 83/136 (61%), Gaps = 6/136 (4%)
 Frame = -1

Query: 62  ELKDDDFEKISELGAGNGGVVFKVSHKPSGLVMARKLIHLEIKPAIRNQIIRELQVLHEC 121
           +   +D + + E+G GN G V K+ HK +  VMA K I   ++   + Q++ +L V+   
Sbjct: 407 DFTSEDMQDMGEIGRGNYGTVNKMRHKITSTVMAVKRIRSTVEEREQKQLLMDLDVVMRS 228

Query: 122 NS-PYIVGFYGAFYSDGEISICMEHMDGGSLDQVLK-----KAGRIPEQILGKVSIAVIK 175
           N+ P+IV FYGA + +G+  ICME M+  SLD+  K         IPE ILGK+++A +K
Sbjct: 227 NNCPFIVQFYGALFKEGDCWICMELMET-SLDKFYKFVYGEMQSSIPENILGKITVATLK 51

Query: 176 GLTYLREKHKIMHRDV 191
            L YL+E+ +I+HRDV
Sbjct: 50  ALNYLKEELRIIHRDV 3
>00300
          Length = 2318

 Score = 95.1 bits (235), Expect = 5e-20,   Method: Compositional matrix adjust.
 Identities = 75/307 (24%), Positives = 140/307 (45%), Gaps = 12/307 (3%)
 Frame = -1

Query: 68   FEKISELGAGNGGVVFKVSHKPSGLVMARKLIHLEIKPAIRNQI---IRELQVLHECNSP 124
            +++ +++G G  G V+   +  +G +MA K   ++ +P    Q+     E+++       
Sbjct: 1652 WQRGNKIGEGQFGKVYTAVNMSTGELMALK--EMKFQPNDLQQLREMCDEIKIFEGIQHE 1479

Query: 125  YIVGFYGAFYSDGEISICMEHMDGGSLDQVLKKAGRIPEQILGKVSIAVIKGLTYLREKH 184
             +V +YG      E+ + ME+ D G++++  K    +PE ++ + +  ++  + +L E  
Sbjct: 1478 NLVKYYGVEVHKDEMLMFMEYCDTGTIEEAAKMG--LPEYLIRRYTREIVLAVNHLHEN- 1308

Query: 185  KIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMA-----NSFVGTRSYMSPERL---- 235
             I+HRD+K +NI + S G +KL DFG S +L          ++ VGT +YM+PE      
Sbjct: 1307 SIVHRDIKGANIFLTSNGHVKLGDFGCSVKLKSHTTMPGEFHNLVGTTAYMAPEVFTQND 1128

Query: 236  QGTHYSVQSDIWSMGLSLVEMAVGRYPIPPPDAKELELLFGCHVEGDAAEXXXXXXXXXX 295
            QG  Y   +DIWS+G  ++EMA G+ P    D                            
Sbjct: 1127 QGG-YGRAADIWSLGCVVIEMATGKRPWHDLDNN-------------------------- 1029

Query: 296  XLSSYGMDSRPPMAIFELLDYIVNEPPPKLPSGVFSLEFQDFVNKCLIKNPAERADLKQL 355
                           ++++  +     P +P  + S+E + F++  +  +PA+RA   QL
Sbjct: 1028 ---------------YQIMYKVGIGHKPAVPDSL-SVEGKHFLDLIMCHDPAQRALASQL 897

Query: 356  MVHAFIK 362
            + H F K
Sbjct: 896  LDHTFTK 876
>01718
          Length = 959

 Score = 94.0 bits (232), Expect = 1e-19,   Method: Compositional matrix adjust.
 Identities = 66/210 (31%), Positives = 115/210 (54%), Gaps = 10/210 (4%)
 Frame = +3

Query: 66  DDF--EKISELGAGNGGVVFKVSHKPSGLVMARKLIHLEIKPAIRNQIIRELQVLHECNS 123
           DDF  EKI   GAG    VFKV+H+ +G VMA K   +    + R+ ++RE+Q+L+    
Sbjct: 150 DDFICEKI---GAGFFSEVFKVTHRITGQVMALK---MNTMTSNRHNMLREVQLLNRLQH 311

Query: 124 PYIVGFYGAFYSDGEISICMEHMDGGSLDQVL-KKAGRIPEQILGKVSIAVIKGLTYLRE 182
             I+ F G    +G++    E++  G+L+Q+L KK   +P     ++++ + +GL YL  
Sbjct: 312 ANILRFMGVCVHEGQLHALTEYIPSGNLEQLLEKKDEELPWTQRIQLTLGLARGLDYLHS 491

Query: 183 KHKIMHRDVKPSNILV----NSRGEIKLCDFGVSGQLIDSMANS---FVGTRSYMSPERL 235
             + +HRD+   NIL+    N      + DFG++ ++ D +       VG+  +M+PE L
Sbjct: 492 T-RFIHRDLTSKNILIRREDNHGYHAVIADFGLATKIPDPLDKEKLPTVGSPYWMAPEVL 668

Query: 236 QGTHYSVQSDIWSMGLSLVEMAVGRYPIPP 265
            G  Y+ ++D++S+G+ + E+   R P  P
Sbjct: 669 NGHFYNERADLFSVGIIMCEIT-ARIPADP 755
>14420
          Length = 528

 Score = 92.4 bits (228), Expect = 3e-19,   Method: Compositional matrix adjust.
 Identities = 57/168 (33%), Positives = 90/168 (53%), Gaps = 2/168 (1%)
 Frame = +2

Query: 97  KLIHLEIKPAIRNQIIRELQVLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLK 156
           K ++L  +P  +  II E+ V+ E  +P IV +  ++    E+ + ME + GGSL  V+ 
Sbjct: 2   KTMNLSQQPK-KELIINEILVMRENQNPNIVNYLDSYLVGEELWVVMEFLAGGSLTDVVT 178

Query: 157 KAGRIPEQILGKVSIAVIKGLTYLREKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLI 216
           +      QI   V    ++ L +L E ++++HRD+K  NIL+   G +KL DFG   QL 
Sbjct: 179 ETCMDEGQI-AAVCRECLQALEFLHE-NQVIHRDIKSDNILLGMDGSVKLTDFGFCAQLS 352

Query: 217 --DSMANSFVGTRSYMSPERLQGTHYSVQSDIWSMGLSLVEMAVGRYP 262
              S  ++ VGT  +M+PE +    Y    DIWS+G+  +EM  G  P
Sbjct: 353 PEQSKRSTMVGTPYWMAPEVVTRKQYGPTVDIWSLGVMCIEMIEGEPP 496
>13212
          Length = 1067

 Score = 90.5 bits (223), Expect = 1e-18,   Method: Compositional matrix adjust.
 Identities = 65/226 (28%), Positives = 110/226 (48%), Gaps = 8/226 (3%)
 Frame = -1

Query: 149  GSLDQVLKKAGR-IPEQILGKVSIAVIKGLTYLREKHKIMHRDVKPSNILVNSRGEIKLC 207
            G+LD ++    + + E  +  V   +   L +L  +H ++HRD+K  N+L+   GE+KL 
Sbjct: 1028 GALDSIMVDLEKPMTEAQICYVCHEMCMALDFLH-RHHVIHRDIKAGNVLLTIDGEVKLA 852

Query: 208  DFGVSGQLIDSMA--NSFVGTRSYMSP-----ERLQGTHYSVQSDIWSMGLSLVEMAVGR 260
            DFGVS +   +    ++F+GT  +M+P     E L+ T Y  ++DIWS+G++L+E A   
Sbjct: 851  DFGVSAKNTQTQQKRDTFIGTPYWMAPEVVLCETLKDTPYDFKADIWSLGVTLIEFAQ-- 678

Query: 261  YPIPPPDAKELELLFGCHVEGDAAEXXXXXXXXXXXLSSYGMDSRPPMAIFELLDYIVNE 320
              I PP+ KE+                                   PM +  L+    ++
Sbjct: 677  --IEPPN-KEMH----------------------------------PMRV--LIKIHKSD 615

Query: 321  PPPKLPSGVFSLEFQDFVNKCLIKNPAERADLKQLMVHAFIKRSDA 366
            PP       ++  F+DF+ KCL+K+P  R    +L+ H F+KR+ A
Sbjct: 614  PPTLEKPKKWTKLFKDFIAKCLVKDPNLRPTAAELLEHPFMKRATA 477
>09606
          Length = 1300

 Score = 87.8 bits (216), Expect = 6e-18,   Method: Compositional matrix adjust.
 Identities = 56/222 (25%), Positives = 104/222 (46%), Gaps = 24/222 (10%)
 Frame = -3

Query: 66   DDFEKISELGAGNGGVVFKVSHKPSGLVMARKLIHLEIKPAIRNQIIRELQVLHECNSPY 125
            ++F    ELG G   +++K   K +   +A   I    +P + N +    ++ H+ + P 
Sbjct: 1115 ENFVLYEELGKGEHSIIYKGRRKGTINFVAIHCIEKCKRPEVTNTV----RMTHDISHPN 948

Query: 126  IVGFYGAFYSDGEISICMEHMDGGSLDQVLKKAGRIPEQILGKVSIAVIKGLTYLREKHK 185
            +V F+  + +   + + +E   GGSL  +L +   +PE  +    I ++ GL Y+     
Sbjct: 947  VVQFHEWYETSNHLWLVVELCTGGSLADILAQDHHLPETSIRDFGIHLVTGLHYIHSLGI 768

Query: 186  IMHRDVKPSNILVNSRGEIKLCDFGVS---GQLIDSMANSFV------------------ 224
            + H D++PS +L+++ G +K  DFG+S   G+ ++ +   F                   
Sbjct: 767  LFH-DLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEAGDQWNIQSAEEMMKQV 591

Query: 225  ---GTRSYMSPERLQGTHYSVQSDIWSMGLSLVEMAVGRYPI 263
               G+ +YM+PE  QG   S+ SD+W++G    EM  G  P 
Sbjct: 590  PTSGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFSGHPPF 465
>01060
          Length = 1800

 Score = 85.5 bits (210), Expect = 4e-17,   Method: Compositional matrix adjust.
 Identities = 67/223 (30%), Positives = 106/223 (47%), Gaps = 14/223 (6%)
 Frame = +1

Query: 67  DFEKISELGAGNGGVVFKVSHKPSGLVMARKLIHLE-IKPAIRNQIIRELQVLHECNSPY 125
           DF+KI   G G  GVV+K  H+ +G  +A K I L   +  + +  IRE+ +L E     
Sbjct: 85  DFQKI---GEGTYGVVYKCRHRATGRKLAMKKIRLRGSEDGVPSSAIREIAMLRELRHTN 255

Query: 126 IVGFYGAFYSDGEISICMEH--MDGGSLDQVLKKAGRIPEQILGKVSIAVIKGLTYLREK 183
           IV        D  + +  E   MD         +   +  +++      ++ G+ +  ++
Sbjct: 256 IVCLEDVIMEDERLFLVFEFLSMDLKMYIDKFPEGVVLDRRLVKSYVFQIVTGIXFCHQR 435

Query: 184 HKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSF----------VGTRSYMSPE 233
            +I+HRD+KP N+L+N  G IK+ DFG        MA +F          V T  Y +PE
Sbjct: 436 -RIVHRDLKPQNLLINHTGAIKIADFG--------MARTFALPVRAYTHEVVTLWYRAPE 588

Query: 234 RLQG-THYSVQSDIWSMGLSLVEMAVGRYPIPPPDAKELELLF 275
            L G + YS   D+WS+G    +M + R PI   D+ E++ LF
Sbjct: 589 ILMGASKYSTPVDVWSIGTIFADMLI-RTPIFKGDS-EIDQLF 711
>21210
          Length = 518

 Score = 84.0 bits (206), Expect = 1e-16,   Method: Compositional matrix adjust.
 Identities = 49/160 (30%), Positives = 78/160 (48%), Gaps = 5/160 (3%)
 Frame = +3

Query: 225 GTRSYMSPERLQ---GTH-YSVQSDIWSMGLSLVEMAVGRYPIPPPDAKELELLFGCHVE 280
           G R YM+PER+     +H Y V+SD+WS+G++L+E+A GR+P                  
Sbjct: 6   GCRPYMAPERIDPRASSHGYDVRSDVWSLGITLMELATGRFPY----------------- 134

Query: 281 GDAAEXXXXXXXXXXXLSSYGMDSRPPMAIFELLDYIVNEPPPKLP-SGVFSLEFQDFVN 339
                                   R  ++IF+ L  +V    P LP  G FS +F +FVN
Sbjct: 135 ------------------------RKWVSIFDQLQQVVRGVAPCLPHDGAFSHDFVNFVN 242

Query: 340 KCLIKNPAERADLKQLMVHAFIKRSDAEEVDFAGWLCSTI 379
           KCL K+  +R    +L+ H F++  + +EVD A ++C+ +
Sbjct: 243 KCLTKDEKQRPKYNKLLAHPFVRLYEEQEVDVASYVCNVL 362
>21808
          Length = 1011

 Score = 79.3 bits (194), Expect = 2e-15,   Method: Compositional matrix adjust.
 Identities = 47/159 (29%), Positives = 79/159 (49%), Gaps = 5/159 (3%)
 Frame = +1

Query: 111 IIRELQVLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKKAGRIPE-QILGKV 169
            + E Q++ +   P ++  Y     D  I I  E M  GSL + L+  GR+ +   L  +
Sbjct: 73  FLAEAQIMKKLRHPKLIQLYAVCTQDDPIFIITELMKNGSLLEFLQGKGRVLKLPALIDI 252

Query: 170 SIAVIKGLTYLREKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTR-- 227
              +  G+ YL E    +HRD+   NILV+    +K+ DFG++  + +    + VG R  
Sbjct: 253 GAQIACGMAYL-ESQNYIHRDLAARNILVSDNNTVKIADFGLARVIKEDEYEARVGARFP 429

Query: 228 -SYMSPERLQGTHYSVQSDIWSMGLSLVE-MAVGRYPIP 264
             + +PE      ++++SD+WS G+ L E +  GR P P
Sbjct: 430 IKWTAPEAANYNRFTIKSDVWSFGILLTETVTYGRVPYP 546
>31885
          Length = 529

 Score = 79.3 bits (194), Expect = 3e-15,   Method: Compositional matrix adjust.
 Identities = 48/155 (30%), Positives = 80/155 (51%), Gaps = 6/155 (3%)
 Frame = -2

Query: 115 LQVLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKKAGRIPEQILGKVSIAVI 174
           + +L   + P++V  + AF  + ++ + ++   GG L   +++     E  +      + 
Sbjct: 519 VDMLTRLDHPFLVNLWYAFQDEEDLFMVVDLFLGGDLRYHMQQEVSFREDCVKFYLCQLA 340

Query: 175 KGLTYLREKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQL-IDSMANSFVGTRSYMSPE 233
             L YLR + KI+HRD+KP NIL++ +G   + DF ++ QL  D +A S  GTR YM+PE
Sbjct: 339 LVLDYLRSQ-KIVHRDIKPDNILLDEQGHCHVTDFNIATQLEDDELATSTSGTRPYMAPE 163

Query: 234 RL-----QGTHYSVQSDIWSMGLSLVEMAVGRYPI 263
                  +   Y    D WS+G+SL E+   R P 
Sbjct: 162 VYGVAINERRGYGFPVDWWSLGVSLFELLKKRRPF 58
>00392
          Length = 668

 Score = 77.0 bits (188), Expect = 1e-14,   Method: Compositional matrix adjust.
 Identities = 50/164 (30%), Positives = 81/164 (49%), Gaps = 7/164 (4%)
 Frame = +3

Query: 106 AIRNQIIRELQVLHECNSPYIVGFYGAFYSDGE-----ISICMEHMDGGSLDQVLKKAGR 160
           A R +   E ++L E   P IV F+  +          I +  E M  G+L   LK+  +
Sbjct: 57  AERQRFKEEAEMLKELQHPNIVRFFDYWEEHNHRNRKVIILVTELMTSGTLKTYLKRFKK 236

Query: 161 IPEQILGKVSIAVIKGLTYLREKHK-IMHRDVKPSNILVNS-RGEIKLCDFGVSGQLIDS 218
              +IL      V+KGL +L  +   ++HRD+K  NI +    G +K+ D G++     S
Sbjct: 237 PNVKILKNWCRQVLKGLYFLHTRTPPVIHRDLKCDNIFITGPTGSVKIGDLGLATLKNQS 416

Query: 219 MANSFVGTRSYMSPERLQGTHYSVQSDIWSMGLSLVEMAVGRYP 262
            A S +GT  +M+PE +   HY    D+++ G+ ++EMA   YP
Sbjct: 417 FAKSVIGTPEFMAPE-MYEEHYDEAVDVYAFGMCMLEMASSEYP 545
>06405
          Length = 1965

 Score = 77.0 bits (188), Expect = 1e-14,   Method: Compositional matrix adjust.
 Identities = 73/309 (23%), Positives = 122/309 (39%), Gaps = 12/309 (3%)
 Frame = +1

Query: 74  LGAGNGGVVFKVSHKPSGLVMARKLIHLEIKPAIRNQIIRELQVLHECNSPYIVGFYGAF 133
           LG G  G V++   K    ++A K +  +      N  + E  ++ E   P +V   G  
Sbjct: 283 LGGGQYGDVYEAMWKRYNKIVAVKTLKEDT--MALNDFLEEAAIMKEMKHPNLVQLLGVC 456

Query: 134 YSDGEISICMEHMDGGSLDQVLKKAGRIPE--QILGKVSIAVIKGLTYLREKHKIMHRDV 191
             +    I  E M  G+L   L+ + R       L  ++  +  G+ YL  K+  +HRD+
Sbjct: 457 TREPPFYIVTEFMPHGNLLDYLRSSTREENGPTALMYMATQIASGMAYLETKN-FIHRDL 633

Query: 192 KPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTR---SYMSPERLQGTHYSVQSDIWS 248
              N LV     +K+ DFG++  + D    + +G +    + +PE L    +S +SDIW+
Sbjct: 634 AARNCLVADSNMVKVADFGLARLMKDDTYTAHIGAKFPIKWTAPEGLAFNRFSTRSDIWA 813

Query: 249 MGLSLVEMAVGRYPIPPPDAKELELLFGCHVEGDAAEXXXXXXXXXXXLSSYGMDSRPPM 308
            G+ L E+A                                         +YGM   P +
Sbjct: 814 FGVLLWELA-----------------------------------------TYGMSPYPGV 870

Query: 309 AIFELLDYIVN----EPPPKLPSGVFSLEFQDFVNKCLIKNPAERADLKQ---LMVHAFI 361
            + E+   +      E PP  P+ V+ L       KC   +P +R   K+   L+ + F 
Sbjct: 871 ELTEVYHLLERGYRMERPPGTPADVYILML-----KCWQWDPKDRPTFKEIHFLLENMFE 1035

Query: 362 KRSDAEEVD 370
           K S  EEV+
Sbjct: 1036KSSICEEVE 1062
>03240
          Length = 1683

 Score = 76.3 bits (186), Expect = 2e-14,   Method: Compositional matrix adjust.
 Identities = 69/248 (27%), Positives = 106/248 (42%), Gaps = 52/248 (20%)
 Frame = -3

Query: 68   FEKISELGAGNGGVVFKVSHKPSGLVMARKLIHLEIKPAIRNQIIR---ELQVLHECNSP 124
            FEKI  LG G  G V       +G++ A K +  +     RNQ+     E  +L E ++ 
Sbjct: 1285 FEKIKTLGVGAFGEVSLCRKNDTGMLYAMKTLR-KSDVLKRNQVAHVKAERDILAEADNE 1109

Query: 125  YIVGFYGAFYSDGEISICMEHMDGGSLDQVLKKAGRIPEQILGKVSIAVIKGLTYLREKH 184
            ++V  Y +F     +   M+++ GG L  +L +   I ++ L +  +A +        + 
Sbjct: 1108 WVVKLYYSFQDHNYLYFVMDYVPGGDLMGLLIRM-EILDEPLARFYVAELVQAIESVHRM 932

Query: 185  KIMHRDVKPSNILVNSRGEIKLCDFG---------------------------VSGQLID 217
              +HRD+KP NIL++  G IKL DFG                           V  QL +
Sbjct: 931  GFIHRDIKPDNILIDRNGHIKLTDFGLCTGFRWTHNSKYYQRDGTHARQDSMEVKCQLDE 752

Query: 218  S-------------------MANSFVGTRSYMSPE---RLQGTHYSVQSDIWSMGLSLVE 255
                                +A+S VGT +Y++PE   RL G  Y+   D WS+G+ L E
Sbjct: 751  QCQCEILKPLERRRKREQRCLAHSLVGTPNYIAPEVLSRLGG--YTSVCDWWSVGVILFE 578

Query: 256  MAVGRYPI 263
            M VG  P 
Sbjct: 577  MLVGHPPF 554
>18484
          Length = 635

 Score = 71.2 bits (173), Expect = 7e-13,   Method: Compositional matrix adjust.
 Identities = 38/119 (31%), Positives = 65/119 (54%), Gaps = 2/119 (1%)
 Frame = +1

Query: 155 LKKAGRIPEQILGKVSIAVIKGLTYLREKHKIMHRDVKPSNILVNSRGEIKLCDFGV--S 212
           +++ G+  E +    +  +  GL +L ++  I++RD+K  N++++S G IK+ DFG+   
Sbjct: 16  IQQEGKFKEPVAAFYAAEIAVGLFFLHDQ-GIIYRDLKLDNVMLDSEGHIKIADFGMCKE 192

Query: 213 GQLIDSMANSFVGTRSYMSPERLQGTHYSVQSDIWSMGLSLVEMAVGRYPIPPPDAKEL 271
           G   D+   +F GT  Y++PE +    YS   D W+ G+ L EM  G+ P    D  EL
Sbjct: 193 GMTGDATTRTFCGTPDYIAPEIVLYQPYSKSVDWWAYGVLLFEMLAGQPPFDGEDEDEL 369
>14126
          Length = 1265

 Score = 68.9 bits (167), Expect = 3e-12,   Method: Compositional matrix adjust.
 Identities = 61/207 (29%), Positives = 101/207 (48%), Gaps = 14/207 (6%)
 Frame = +3

Query: 68  FEKISELGAGNGGVVFKVSH-KPSGLVMARKLIHL----EIKPAIRNQIIRELQVLHECN 122
           +E+++ +G G  G V+K    +  G  +A K I L    E  P +  + I  L+ L +  
Sbjct: 195 YEEVAVIGNGAYGTVYKARDLRNQGEFVAMKRIRLNNTEEGMPMMAIREISMLKQLEQYE 374

Query: 123 SPYIVGFYGAFY---SDGEI--SICMEHMDGGSLDQVLKKA---GRIPEQILGKVSIAVI 174
            P +V      +   +D EI  ++  E+++   L   L K    G  P++I   + + ++
Sbjct: 375 HPNVVRLLDVSHNTITDREIRLNLVFEYIEH-DLATYLAKCPSPGLGPDRI-KDLMLQLL 548

Query: 175 KGLTYLREKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMA-NSFVGTRSYMSPE 233
            G+ +L   ++I+HRD+KP N+L++  G +KL DFG++      MA  + V T  Y SPE
Sbjct: 549 NGVDFL-HSNRIVHRDLKPQNLLISKDGRLKLADFGLARIYSFHMALTTVVVTLWYRSPE 725

Query: 234 RLQGTHYSVQSDIWSMGLSLVEMAVGR 260
            L    Y    DIWS G    E+   R
Sbjct: 726 VLMQAEYGTSVDIWSCGCIFAELFTRR 806
>01756
          Length = 1858

 Score = 68.9 bits (167), Expect = 3e-12,   Method: Compositional matrix adjust.
 Identities = 65/221 (29%), Positives = 104/221 (47%), Gaps = 21/221 (9%)
 Frame = -3

Query: 64   KDDDFEKISELGAGNGGVVFKVSHKPSGLVMARKLIHLEI-KPAIRNQIIRELQVLHECN 122
            +D  +EK++++G G  G VFK   K +  V+A K + ++  K       +RE+++L   N
Sbjct: 1748 EDAKYEKLAKIGQGTFGEVFKARCKKTKQVVAMKKVLMDNEKEGFPITALREIKILQLLN 1569

Query: 123  SPYIVG--------------FYGAFYSDGEISICMEHMDGGSLDQVLKKAGRIPEQILGK 168
               +V               +   FY   E     EH   G L   +     +PE  + +
Sbjct: 1568 HENVVDLIEICSTKATSANRYKSMFYLVFEFC---EHDLAGLLSN-MSVVFNLPE--IKE 1407

Query: 169  VSIAVIKGLTYLREKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMA--NSF--- 223
            V   ++ GL Y+  ++KI+HRD+K +NIL+  +G +KL DFG++     ++   N +   
Sbjct: 1406 VMKQLMNGLYYI-HRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNR 1230

Query: 224  VGTRSYMSPERLQG-THYSVQSDIWSMGLSLVEMAVGRYPI 263
            V T  Y  PE L G  +YS   D W  G  + EM   R PI
Sbjct: 1229 VVTLWYRPPELLLGDRNYSTAIDQWGAGCIMAEMWT-RNPI 1110
>19301
          Length = 712

 Score = 67.0 bits (162), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 54/164 (32%), Positives = 78/164 (47%), Gaps = 8/164 (4%)
 Frame = +2

Query: 57  KQKVGELKDDD-----FEKISEL---GAGNGGVVFKVSHKPSGLVMARKLIHLEIKPAIR 108
           K    ELK  D     FE I++L   G+G  G VF       G + A ++   +++  I+
Sbjct: 254 KAAAAELKQQDDWEIPFESITDLEWLGSGAQGAVFL------GKLCAEEVAVKKVRD-IK 412

Query: 109 NQIIRELQVLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKKAGRIPEQILGK 168
              IR L+ L   N P I+ F G         I ME+   G L +VL+    IP  ++  
Sbjct: 413 ETDIRNLRKL---NHPNIISFKGVCTQAPCYCIIMEYCPYGQLYEVLRDGKEIPPALVLD 583

Query: 169 VSIAVIKGLTYLREKHKIMHRDVKPSNILVNSRGEIKLCDFGVS 212
            S  +  G+ YL   HKI+HRD+K  N+LV     +K+ DFG S
Sbjct: 584 WSKQIASGMNYLHS-HKIIHRDLKSPNVLVAKNDVVKISDFGTS 712
>13066
          Length = 551

 Score = 66.6 bits (161), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 46/165 (27%), Positives = 80/165 (48%), Gaps = 8/165 (4%)
 Frame = +3

Query: 94  MARKLIHLEIKPA--IRNQIIRELQVLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSL 151
           +A K+I  E  P   +     REL +L + + PYI+  +       +  I M   + G L
Sbjct: 60  LACKIIDKEKAPVDFVEKFFPRELDLLTKLDHPYIIQIHSILQRXPKNFIFMRFAERGDL 239

Query: 152 DQVLKKAGRIPEQILGKVSIAVIKGLTYLREKHKIMHRDVKPSNILVNSRGEIKLCDFGV 211
              +++ G + E+        +   L YL   + + HRD+K  NIL++S   +KL DFG 
Sbjct: 240 LTYIQEVGFVKEKQAKIWFYQMTTALNYLHS-YDVAHRDLKCENILLSSHFNVKLADFGF 416

Query: 212 SGQLIDS-----MANSFVGTRSYMSPERLQGTHYSVQ-SDIWSMG 250
           +   I       M+ ++ G+ +Y +PE + G  Y+ + +D WS+G
Sbjct: 417 ACACITESGEKYMSRTYCGSAAYAAPEIVYGAPYAPKVADAWSLG 551
>27405
          Length = 532

 Score = 65.1 bits (157), Expect = 5e-11,   Method: Compositional matrix adjust.
 Identities = 38/126 (30%), Positives = 70/126 (55%), Gaps = 1/126 (0%)
 Frame = -3

Query: 123 SPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKKAGRIPEQILGKVSIAVIKGLTYLRE 182
           SP+IV    AF +  ++   ++ M+GG L   L + G   E+ +   +  V+ GL ++  
Sbjct: 377 SPFIVCMTYAFQTPEKLCFILDLMNGGDLHYHLSQHGVFTEKEVRFYAAEVMLGLEHMHS 198

Query: 183 KHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERL-QGTHYS 241
           +  +++RD+KP+NIL++  G +++ D G++        ++ VGT  YM+PE L +G  Y 
Sbjct: 197 RF-VVYRDLKPANILLDENGHVRISDLGLACDFSKKKPHASVGTHGYMAPEVLMKGQAYD 21

Query: 242 VQSDIW 247
             +D W
Sbjct: 20  SSAD-W 6
>19761
          Length = 473

 Score = 64.7 bits (156), Expect = 7e-11,   Method: Compositional matrix adjust.
 Identities = 35/93 (37%), Positives = 54/93 (58%), Gaps = 3/93 (3%)
 Frame = -3

Query: 161 IPEQILGKVSIAVIKGLTYLREKHK-IMHRDVKPSNILVNSRGEIKLCDFGVSGQLID-- 217
           +PE+++    +     L Y+      I+HRD+KP NI V  +G+++L D G++ +L    
Sbjct: 432 LPERLIVCWLMQTASALNYMHTHTPVILHRDLKPQNIYVTEKGDVRLGDLGLARKLTGPA 253

Query: 218 SMANSFVGTRSYMSPERLQGTHYSVQSDIWSMG 250
             A S VGT  Y+SPE L    Y+ +SDIWS+G
Sbjct: 252 DFATSQVGTIMYLSPEILSQQPYNSKSDIWSLG 154
>37602
          Length = 804

 Score = 60.5 bits (145), Expect(2) = 9e-11,   Method: Compositional matrix adjust.
 Identities = 31/88 (35%), Positives = 49/88 (55%)
 Frame = -1

Query: 122 NSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKKAGRIPEQILGKVSIAVIKGLTYLR 181
           N    VG++ ++    ++ I ME+  GGS+  +    G + E  +  V    +KGL YL 
Sbjct: 345 NIQTFVGYFDSYLRREKLWIAMEYCGGGSMQDIYHVTGPLTEPQIAFVCRETLKGLHYLH 166

Query: 182 EKHKIMHRDVKPSNILVNSRGEIKLCDF 209
            + K MHRD+K +NIL+   G++KL DF
Sbjct: 165 RRGK-MHRDIKGANILLTEEGDVKLADF 85

 Score = 23.5 bits (49), Expect(2) = 9e-11,   Method: Compositional matrix adjust.
 Identities = 10/19 (52%), Positives = 13/19 (68%)
 Frame = -2

Query: 66  DDFEKISELGAGNGGVVFK 84
           DDFE I  +G+G  G V+K
Sbjct: 509 DDFELIQRVGSGTYGDVYK 453
>07291
          Length = 833

 Score = 63.9 bits (154), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 37/110 (33%), Positives = 60/110 (54%), Gaps = 8/110 (7%)
 Frame = +1

Query: 173 VIKGLTYLREKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLI--------DSMANSFV 224
           +  G+ YL+E  K++HR++   N +V   G ++L D+GV+G L         DS A   V
Sbjct: 76  IADGMAYLQEV-KVVHRNLAARNCIVTEDGRLQLSDYGVTGSLFPQSYYTADDSPARDLV 252

Query: 225 GTRSYMSPERLQGTHYSVQSDIWSMGLSLVEMAVGRYPIPPPDAKELELL 274
               +M+PE +   H+S +SD+W+ G+ L E+ + R   P PD +   LL
Sbjct: 253 ---KWMAPETIDNFHFSSKSDVWAFGVVLWEL-LTRGITPYPDVENSSLL 390
>28638
          Length = 1458

 Score = 63.5 bits (153), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 35/81 (43%), Positives = 48/81 (59%), Gaps = 2/81 (2%)
 Frame = -1

Query: 185 KIMHRDVKPSNILVNS--RGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSV 242
            I+H D+KP NIL+ +  R  IK+ DFG S QL   +   ++ +R Y SPE L G  Y +
Sbjct: 771 NIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQ-YIQSRFYRSPEVLLGVPYDL 595

Query: 243 QSDIWSMGLSLVEMAVGRYPI 263
             D+WS+G  LVEM  G  P+
Sbjct: 594 AIDMWSLGCILVEMHTGEPPL 532
>30755
          Length = 1137

 Score = 63.2 bits (152), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 33/93 (35%), Positives = 49/93 (52%), Gaps = 2/93 (2%)
 Frame = +2

Query: 173 VIKGLTYLREKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLID--SMANSFVGTRSYM 230
           +I  L YL  +  I++RD+K  N+L++  G IK+ DFG+  + I       +F GT  Y+
Sbjct: 59  IISALGYLHSQ-GIIYRDLKLENLLLDKDGHIKVADFGLCKEDITYGRTTKTFCGTPEYL 235

Query: 231 SPERLQGTHYSVQSDIWSMGLSLVEMAVGRYPI 263
           +PE L    Y    D W  G+ + EM  GR P 
Sbjct: 236 APEVLDDNDYGRAVDWWGTGVVMYEMICGRLPF 334
>28157
          Length = 400

 Score = 58.5 bits (140), Expect = 4e-09,   Method: Compositional matrix adjust.
 Identities = 38/120 (31%), Positives = 64/120 (53%), Gaps = 6/120 (5%)
 Frame = +3

Query: 108 RNQIIRELQVLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKKAGRIPEQILG 167
           +   ++EL+ L   + P IV  YGA   D  + + ME+ +GGSL  VL  +G  P+    
Sbjct: 42  KKSFMQELKQLSRVSHPNIVCLYGAC-RDHPVCLVMEYAEGGSLYNVLHGSGPQPQYTAA 218

Query: 168 KVSIAVIK---GLTYLR--EKHKIMHRDVKPSNILVNSRG-EIKLCDFGVSGQLIDSMAN 221
                +++   G+ YL   +   ++HRD+KP N+L+   G ++K+CDFG +  +   M N
Sbjct: 219 HAMNWLLQCALGVEYLHGMKPKALIHRDLKPPNLLLIQCGTKLKICDFGTACDIHTHMTN 398
>26560
          Length = 398

 Score = 58.2 bits (139), Expect = 5e-09,   Method: Compositional matrix adjust.
 Identities = 32/110 (29%), Positives = 60/110 (54%), Gaps = 1/110 (0%)
 Frame = -1

Query: 155 LKKAGRIPEQILGKVSIAVIKGLTYLREKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQ 214
           L + G   E+ +   +  V+ GL ++  +  +++RD+KP+NIL++  G +++ D G++  
Sbjct: 383 LSQHGVFTEKEVRFYAAEVMLGLEHMHSRF-VVYRDLKPANILLDENGHVRISDLGLACD 207

Query: 215 LIDSMANSFVGTRSYMSPERL-QGTHYSVQSDIWSMGLSLVEMAVGRYPI 263
                 ++ VGT  YM+PE L +G  Y   +D +S G  L ++  G  P 
Sbjct: 206 FSKKRPHASVGTHGYMAPEVLMKGQSYDSSADWFSFGCMLYKLLKGHSPF 57
>29581
          Length = 1278

 Score = 58.2 bits (139), Expect = 6e-09,   Method: Compositional matrix adjust.
 Identities = 41/112 (36%), Positives = 66/112 (58%), Gaps = 6/112 (5%)
 Frame = -2

Query: 169  VSIAVIKGLTYLREKHKIMHRDVKPSNILVNSRGEIKLCDFGVS---GQLIDSMANSFVG 225
            + + ++KGL YL E   I+HRD+K SN+L+  +G +K+ DFG++   G+    M    V 
Sbjct: 1034 IVLQLLKGLRYLHEAF-IIHRDLKVSNLLMTDKGCVKIADFGLARNYGKPQKPMTPKVV- 861

Query: 226  TRSYMSPERLQGTH-YSVQSDIWSMGLSLVEMAVGRYPIPP--PDAKELELL 274
            T  Y +PE L G+  +S   D+WS G  L E+ +G  P+ P   D +++EL+
Sbjct: 860  TLWYRAPELLFGSKTHSTAIDMWSAGCILGEL-LGHKPLMPGRSDLQQIELI 708
>09007
          Length = 1440

 Score = 57.0 bits (136), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 42/159 (26%), Positives = 76/159 (47%), Gaps = 11/159 (6%)
 Frame = -1

Query: 109 NQIIRELQVLHECNSPYIVGFYGAFYSDG-EISICMEHMDGGSLDQVLKK-AGRIPEQI- 165
            + ++E  ++   +   IV  YG    +G +I +  E     SL + +K+ + R+   + 
Sbjct: 741 QEFLKETAIMQMLDHENIVRVYGVVMDNGADIMLVTELAPMRSLLECVKEVSARVDFSVP 562

Query: 166 -LGKVSIAVIKGLTYLREKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQL-------ID 217
            L   S  V  G++YL  K +++HRD+   NIL+ S+ ++K+ D GVSG L         
Sbjct: 561 RLCDFSQQVCDGMSYLESK-RLVHRDLAARNILLFSKSKVKISDVGVSGALGAGKEYYQS 385

Query: 218 SMANSFVGTRSYMSPERLQGTHYSVQSDIWSMGLSLVEM 256
                     ++ +PE  +   +S  SD+W+ G+ L E 
Sbjct: 384 QQTIHLQNAVAWCAPESFRNLCFSSASDVWAFGVLLWEF 268
>11185
          Length = 473

 Score = 57.0 bits (136), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 36/128 (28%), Positives = 60/128 (46%), Gaps = 24/128 (18%)
 Frame = +1

Query: 171 IAVIKGLTYLREKHKIMHRDVKPSNILVNSRGEIKLCDFGVS---GQLIDSMANSFV--- 224
           I ++ GL Y+     + H D++PS +L+++ G +K  DFG+S   G+ ++ +   F    
Sbjct: 22  IHLVTGLHYIHSLGILFH-DLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEAG 198

Query: 225 ------------------GTRSYMSPERLQGTHYSVQSDIWSMGLSLVEMAVGRYPIPPP 266
                             G+ +YM+PE  QG   S+ SD+W++G    EM  G      P
Sbjct: 199 DQWNIQSAEEMMKQVPTSGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFSGSRLSAKP 378

Query: 267 DAKELELL 274
             + L LL
Sbjct: 379 SPEFLNLL 402
>00715
          Length = 1788

 Score = 56.6 bits (135), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 49/207 (23%), Positives = 91/207 (43%), Gaps = 25/207 (12%)
 Frame = +1

Query: 81  VVFKVSHKPSGLVMARKLIHLEIKPAIRNQIIRELQVLHECNSPYIVGFYGAFYSDGEIS 140
           V  K+ HK S    A       ++ +  N+++     L   N   I+G       +    
Sbjct: 7   VAVKIYHKRSSNPRA-------LRQSYSNELLAFRCGLRHVNVVSILGATSLHRFEDGAW 165

Query: 141 ICMEHMDGGSLDQVLKKAGR-IPEQILGKVSIAVIKGLTYLREKHKIMHRDVKPSNILVN 199
           + ME++   +L  +L    + I   +   +++ + +GL YL   + I+H D+KP+N L+ 
Sbjct: 166 LAMEYVGPLNLQTILNDHQQDIDSSMRLSLALQMARGLHYLHSIN-IVHLDLKPANCLLT 342

Query: 200 SRGEIKLCDFGVSGQLI------------------------DSMANSFVGTRSYMSPERL 235
              ++++ DFG   QL                          +  N   GT +Y +PE L
Sbjct: 343 RDLKLRIADFGCCHQLTPTGLDMGEREGGMAGNELELTPVQGAWKNELAGTLAYRAPELL 522

Query: 236 QGTHYSVQSDIWSMGLSLVEMAVGRYP 262
           +G   SV+SD++S+G++L +M   + P
Sbjct: 523 KGLQPSVRSDVYSLGITLWQMCTRQGP 603
>04852
          Length = 1462

 Score = 56.2 bits (134), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 67/307 (21%), Positives = 117/307 (38%), Gaps = 33/307 (10%)
 Frame = +1

Query: 85  VSHKPSGLVMARKLIHLEIKPAIRNQ-IIRELQVLHECNSP----YIVGFYGAFYSDGEI 139
           +   P    +A K++  +I  A+  Q  ++ELQV+           IV F G     G +
Sbjct: 1   IGRVPKASTVAVKMLR-DIVTAVEEQDFVQELQVMKAVKKMGSHINIVNFLGCCTQGGPL 177

Query: 140 SICMEHMDGGSLDQVLKKA-------GR------------------IPEQILGKVSIAVI 174
            + +E    G+L   L+         G+                  I  + L   +  + 
Sbjct: 178 WVIVEFAKNGNLRDFLESCRDGINGYGKFVSPQDPGWYTKTPGGHVIRRKNLLSYAFQIA 357

Query: 175 KGLTYLREKHKIMHRDVKPSNILVNSRGEIKLCDFGVS--GQLIDSMANSFVGTRSYMSP 232
           +G+ +L  + K +HRD+   N+LV     +K+ DFG+S  G      +   +  + +M+P
Sbjct: 358 RGMEFLASR-KCIHRDLAARNVLVTEEHVLKIADFGLSRTGDYYKKRSGGRLPVK-WMAP 531

Query: 233 ERLQGTHYSVQSDIWSMGLSLVEM-AVGRYPIPPPDAKELELLFGCHVEGDAAEXXXXXX 291
           E L    Y+ +SD+WS G+ L E+ ++G  P      +EL                    
Sbjct: 532 EALFDMRYTTKSDVWSFGVVLWEIFSLGGMPYASIPNEEL-------------------- 651

Query: 292 XXXXXLSSYGMDSRPPMAIFELLDYIVNEPPPKLPSGVFSLEFQDFVNKCLIKNPAERAD 351
                               +LLD     P P+L SG         + +C +  P++R +
Sbjct: 652 ------------------YSKLLDDAYRMPRPELASG----NLYAIMERCWLNRPSDRPE 765

Query: 352 LKQLMVH 358
             QL+ H
Sbjct: 766 FSQLVGH 786
>04591
          Length = 1117

 Score = 55.8 bits (133), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 34/87 (39%), Positives = 50/87 (57%), Gaps = 3/87 (3%)
 Frame = -2

Query: 173 VIKGLTYLREKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDS--MANSFVGTRSYM 230
           ++ GL Y+  K +I+HRD+K +NIL+   G +KL DFG+S   + S  + N  V T  Y 
Sbjct: 870 LLNGLFYIHTK-QILHRDIKAANILLTRDGVLKLADFGLSRPWVKSKRLTNRVV-TLWYR 697

Query: 231 SPERLQGTH-YSVQSDIWSMGLSLVEM 256
            PE L G   Y  + D+W +G  + EM
Sbjct: 696 PPELLLGEREYGPEIDMWGVGCIMAEM 616
>21433
          Length = 590

 Score = 55.8 bits (133), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 29/79 (36%), Positives = 47/79 (59%)
 Frame = +2

Query: 185 KIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQS 244
           K++HRD+KP N+L+  +G++K+ DFG S     S   +  GT  Y+ PE ++G  +    
Sbjct: 227 KVIHRDIKPENLLLGLKGDLKIADFGWSVHAPSSRRTTMCGTLDYLPPEMVEGKTHDENV 406

Query: 245 DIWSMGLSLVEMAVGRYPI 263
           D+WS+G+   E  VG  P+
Sbjct: 407 DLWSLGVLCYEFLVGTPPL 463
>17975
          Length = 449

 Score = 55.8 bits (133), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 29/115 (25%), Positives = 65/115 (56%), Gaps = 2/115 (1%)
 Frame = +3

Query: 108 RNQIIRELQVLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSL-DQVLKKAGRIPEQIL 166
           R+ + +E++ +     P +V  Y    +  ++ + +E  DGG + D +++ +G + E++ 
Sbjct: 96  RSHLFQEVRCMKLVQHPNVVRLYEVIDTQTKLYLILELGDGGDMYDYIMRHSGGLEEKLA 275

Query: 167 GKVSIAVIKGLTYLREKHKIMHRDVKPSNILVNSR-GEIKLCDFGVSGQLIDSMA 220
            +    +++ ++Y  + H ++HRD+KP N++   + G +KL DFG S  L+ + A
Sbjct: 276 KRYFRQIVEAISYCHKLH-VVHRDLKPENVVFFEKPGLVKLTDFGFSTCLLQAKA 437
>27546
          Length = 426

 Score = 55.8 bits (133), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 34/106 (32%), Positives = 52/106 (49%)
 Frame = -1

Query: 113 RELQVLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKKAGRIPEQILGKVSIA 172
           REL++L   + P I+  +       +I I M + + G +   +KK G I E         
Sbjct: 333 RELEILTRLDHPNIIQIHSILQRGPKIFIFMRYAEKGDMLSHIKKTGPIDEAQTKVWFFQ 154

Query: 173 VIKGLTYLREKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDS 218
           + K L YL   H I HRD+K  NIL++ R  +K+ DFG +    D+
Sbjct: 153 MAKALQYLHS-HDIAHRDLKCENILLSKRLNVKIADFGFARYCRDA 19
>14477
          Length = 493

 Score = 55.1 bits (131), Expect = 4e-08,   Method: Compositional matrix adjust.
 Identities = 48/165 (29%), Positives = 87/165 (52%), Gaps = 4/165 (2%)
 Frame = -1

Query: 73  ELGAGNGGVVFKVSHKPSGL---VMARKLIHLEIKPAIRNQIIRELQVLHECNSPYIVGF 129
           +LGAGN G V K   +       V  + L + ++ P++++++I+E +V+ + +  +IV  
Sbjct: 469 KLGAGNFGSVMKGVCRLDDREIPVAIKVLKNADLDPSVQSELIKEAEVMKKMDHMHIVRL 290

Query: 130 YGAFYSDGE-ISICMEHMDGGSLDQVLKKAGRIPEQILGKVSIAVIKGLTYLREKHKIMH 188
            G    +GE + + +E    G L++ L K   +P   + ++   V +G+ YL E +K +H
Sbjct: 289 IG--LCEGETMMLVLELAKLGPLNKFLPKNKHLPLWNILELMWQVSQGMEYL-EANKFVH 119

Query: 189 RDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPE 233
           RD+   NIL+      K+ DFG+S  L  S  N++     YM+ E
Sbjct: 118 RDLAARNILLCDEHFAKISDFGMSKTL--SRENNY-----YMAQE 5
>15910
          Length = 1361

 Score = 53.9 bits (128), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 34/117 (29%), Positives = 63/117 (53%), Gaps = 4/117 (3%)
 Frame = +2

Query: 151 LDQVLKKAGRIPEQILGKVSIAVIKGLTYLREKHKIMHRDVKPSNIL---VNSRGEIKLC 207
            D+++ + G+  E+   +    ++ G+ Y+   + ++HRD+KP N+L   +    ++KL 
Sbjct: 428 FDRIVTR-GQYTEKDAARAISDILHGVQYIH-ANGVVHRDLKPENLLYECMTDDSKLKLA 601

Query: 208 DFGVSGQLIDSMANSFV-GTRSYMSPERLQGTHYSVQSDIWSMGLSLVEMAVGRYPI 263
           DFG+S  +   +  S V GT  Y +PE L+G  Y+   D+WS+G+    +  G  P 
Sbjct: 602 DFGLSRIIEPEVQMSTVCGTPGYCAPEVLKGDKYTPSVDMWSVGVIAYILLCGYEPF 772
>12786
          Length = 460

 Score = 53.9 bits (128), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 33/102 (32%), Positives = 49/102 (48%), Gaps = 24/102 (23%)
 Frame = -3

Query: 186 IMHRDVKPSNILVNSRGEIKLCDFGVSGQL----IDSMANSFVGTRSYMSPERLQGT--- 238
           ++H D+KP+N ++ + G +KL DFG++  L       + +S VGT SYMSPE +      
Sbjct: 347 VIHSDLKPANFMLVA-GNLKLIDFGIANTLQQDKTSVLKDSRVGTPSYMSPEAIMAACDD 171

Query: 239 -----------------HYSVQSDIWSMGLSLVEMAVGRYPI 263
                               V+SD+WS+G  L  M  GR P 
Sbjct: 170 SADDSMEEDGHRTKPKYKVGVRSDVWSLGCILYNMVYGRTPF 45
>01966
          Length = 1735

 Score = 53.1 bits (126), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 40/157 (25%), Positives = 73/157 (46%), Gaps = 6/157 (3%)
 Frame = -1

Query: 87   HKPSGLVMARKLIHLE-IKPAIRNQIIRELQVLHECNSPYIVGFYGAFYSDGEISICMEH 145
            H+ +G  +A K I L   +  + +  IRE+ +L E     IV        D  + +  E 
Sbjct: 1648 HRATGRKLAMKKIRLRGSEDGVPSSAIREIAMLRELRHTNIVCLEDVIMEDERLFLVFEF 1469

Query: 146  --MDGGSLDQVLKKAGRIPEQILGKVSIAVIKGLTYLREKHKIMHRDVKPSNILVNSRGE 203
              MD         +   +  +++      ++ G+ +  ++ +I+HRD+KP N+L+N  G 
Sbjct: 1468 LSMDLKMYIDKFPEGVVLDRRLVKSYVFQIVTGINFCHQR-RIVHRDLKPQNLLINHTGA 1292

Query: 204  IKLCDFGVSGQL---IDSMANSFVGTRSYMSPERLQG 237
            IK+ DFG++      + +  +  V T  Y +PE L G
Sbjct: 1291 IKIADFGMARTFALPVRAYTHEVV-TLWYRAPEILMG 1184
>07940
          Length = 1336

 Score = 52.0 bits (123), Expect = 4e-07,   Method: Compositional matrix adjust.
 Identities = 35/104 (33%), Positives = 54/104 (51%), Gaps = 5/104 (4%)
 Frame = -3

Query: 173 VIKGLTYLREKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQL--IDSMANSFVGTR--S 228
           V +G+ YL  K  I HRD+   N+LV     +K+ DFG++  L   D    +  G     
Sbjct: 320 VARGMEYLASKQCI-HRDLAARNVLVAEEYVLKIADFGLTRNLQQFDYYRKTTDGRLPVK 144

Query: 229 YMSPERLQGTHYSVQSDIWSMGLSLVEM-AVGRYPIPPPDAKEL 271
           +M+PE L    Y+ +SD+WS G+ L E+  +G  P P    ++L
Sbjct: 143 WMAPEALFDRKYTSKSDVWSYGVLLWEIFTLGGNPYPSVPVEDL 12
>04138
          Length = 800

 Score = 51.6 bits (122), Expect = 5e-07,   Method: Compositional matrix adjust.
 Identities = 34/91 (37%), Positives = 49/91 (53%), Gaps = 6/91 (6%)
 Frame = +1

Query: 179 YLREKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMA--NSF---VGTRSYMSPE 233
           Y   ++KI+HRD+K +NIL+  +G +KL DFG++     ++   N +   V T  Y  PE
Sbjct: 55  YYIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRVVTLWYRPPE 234

Query: 234 RLQG-THYSVQSDIWSMGLSLVEMAVGRYPI 263
            L G  +YS   D W  G  + EM   R PI
Sbjct: 235 LLLGDRNYSTAIDQWGAGCIMAEMWT-RNPI 324
>21079
          Length = 878

 Score = 48.9 bits (115), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 36/144 (25%), Positives = 73/144 (50%), Gaps = 5/144 (3%)
 Frame = +1

Query: 124 PYIVGFYGAFYSDGEISICMEHMDGGSL-DQVLKKAGRIPEQILGKVSIAVIKGLTYLRE 182
           P ++  + AF +   + + ME +  G L ++V++    + E+        +  G+ Y+  
Sbjct: 4   PKLLMLWDAFEAPRTMVLVMEFVGAGELFERVIRDDFVLTERDCVHFVRQICSGVGYMHT 183

Query: 183 KHKIMHRDVKPSNILV--NSRGEIKLCDFGVSGQLI--DSMANSFVGTRSYMSPERLQGT 238
           +  I+H D+KP N+L   ++  +IK+ DFG++      DS+   F GT  +++PE +   
Sbjct: 184 Q-SILHLDLKPENVLCVSDNSNQIKIIDFGLARFYKPGDSLQVLF-GTPEFIAPEVVNYD 357

Query: 239 HYSVQSDIWSMGLSLVEMAVGRYP 262
             +  +D+WS+G+    +  G  P
Sbjct: 358 EINFTTDMWSIGVICYILLSGLSP 429
>14116
          Length = 1017

 Score = 48.5 bits (114), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 46/202 (22%), Positives = 93/202 (46%), Gaps = 18/202 (8%)
 Frame = -1

Query: 73  ELGAGNGGVV----FKVSHKPSGLVMARKLIH------LEIKPAIRNQIIRELQVLHECN 122
           E+G GN G V      +  +   +++A K +H      +E++  ++  +I  ++  H  N
Sbjct: 615 EIGKGNFGCVKRGFLTLPEQKGDILVAVKTLHNNNPREIELQSFLQEALI--MKDFHHSN 442

Query: 123 SPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKKAGRIP---EQILGKVSIAVIKGLTY 179
              ++G       D    + +  M  G L   ++     P   + I+  V IA  +G+ Y
Sbjct: 441 VLTLIGI--CLNLDDMPLVVLPFMKHGDLLTYIRDDQHQPTIKDLIMYGVDIA--RGMDY 274

Query: 180 LREKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRS-----YMSPER 234
           L    K +HRD+   N +++    +K+ DFG++  + +    S    ++     +M+ E 
Sbjct: 273 L-AGLKFVHRDLAARNCMLDEDFHVKVADFGLARDIYEKEYYSSENKKAKLPVKWMALES 97

Query: 235 LQGTHYSVQSDIWSMGLSLVEM 256
           L+  +Y  ++D+WS G+ L E+
Sbjct: 96  LEKGNYDSKTDVWSYGVVLWEL 31
>01392
          Length = 1806

 Score = 48.5 bits (114), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 38/119 (31%), Positives = 55/119 (46%), Gaps = 15/119 (12%)
 Frame = -1

Query: 159  GRIPEQILGKVSIAVIKGLTYLREKHKIMHRDVKPSNILVNSRGE---IKLCDFGV-SGQ 214
            G + E+    V   + + L +L  K  I HRD+KP NIL     +   +K+CDF + SG 
Sbjct: 1806 GHLCEREASLVVRHIARALDFLHSK-GIAHRDLKPENILCEHLDDVVPVKICDFDLASGI 1630

Query: 215  LIDSMANSF------VGTRSYMSPERLQGT-----HYSVQSDIWSMGLSLVEMAVGRYP 262
              D            VG+  YM+PE +         Y  + D+WS+G+ L  M  G YP
Sbjct: 1629 SCDGDGTKTPELLTPVGSAEYMAPEVVDAWVGDSFSYDKRCDLWSLGIILYIMLCG-YP 1456
>32691
          Length = 295

 Score = 48.1 bits (113), Expect = 6e-06,   Method: Composition-based stats.
 Identities = 21/40 (52%), Positives = 29/40 (72%)
 Frame = +1

Query: 330 FSLEFQDFVNKCLIKNPAERADLKQLMVHAFIKRSDAEEV 369
           +S EF DFV+KCL+KNP  RA    L+ H FIK+++A E+
Sbjct: 85  WSTEFIDFVSKCLVKNPENRATAVDLLQHDFIKKAEACEI 204
>17253
          Length = 483

 Score = 47.8 bits (112), Expect = 8e-06,   Method: Compositional matrix adjust.
 Identities = 36/127 (28%), Positives = 61/127 (48%), Gaps = 15/127 (11%)
 Frame = -1

Query: 106 AIRNQIIRELQVLHEC-NSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKKAGRIPEQ 164
           A +++ +REL ++ +    P +V F G         I ME    G L   L+K  R P++
Sbjct: 423 AEKSEFLRELSIMRKLPRHPNVVSFMGCCTMSDPALILMEFCCHGDLLSFLRK--RRPDR 250

Query: 165 ILGKVSIA--------------VIKGLTYLREKHKIMHRDVKPSNILVNSRGEIKLCDFG 210
            +   S A              V +G+ ++   +KI+HRDV   N+L++ R   K+ DFG
Sbjct: 249 TVFLTSTANDLTARDFFSFALHVARGMAHV-ANNKIVHRDVAARNVLISERNVCKVSDFG 73

Query: 211 VSGQLID 217
           +S ++ D
Sbjct: 72  LSRRVGD 52
>03508
          Length = 1463

 Score = 47.0 bits (110), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 27/83 (32%), Positives = 43/83 (51%), Gaps = 3/83 (3%)
 Frame = +1

Query: 186  IMHRDVKPSNILVNSRG-EIKLCDFGVSGQLIDSMA-NSFVGTRSYMSPERLQGTH-YSV 242
            IMHRDVKP N++++    +++L D+G++      M  N  V +R +  PE L     Y  
Sbjct: 934  IMHRDVKPHNVMIDHENKKLRLIDWGLAEFYHPGMEYNVRVASRYFKGPELLLDYQMYDY 1113

Query: 243  QSDIWSMGLSLVEMAVGRYPIPP 265
              D+WS+G     M   + P+ P
Sbjct: 1114 SLDMWSLGCMFASMIFRKEPLLP 1182
>25019
          Length = 730

 Score = 47.0 bits (110), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 24/62 (38%), Positives = 36/62 (58%), Gaps = 2/62 (3%)
 Frame = +3

Query: 195 NILVNSRGEIKLCDFGVSGQLIDS--MANSFVGTRSYMSPERLQGTHYSVQSDIWSMGLS 252
           N+L++  G +KL DFG+  + I    + ++F GT  YM+PE L  T +    D WS+G S
Sbjct: 264 NVLLDKDGHVKLTDFGLCKEAITGTRVTHTFCGTIEYMAPEILTRTGHGKAVDWWSLGSS 443

Query: 253 LV 254
            V
Sbjct: 444 YV 449
>07836
          Length = 1478

 Score = 47.0 bits (110), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 39/132 (29%), Positives = 61/132 (46%), Gaps = 19/132 (14%)
 Frame = -1

Query: 145  HMDGGSLDQVLKKAGRIPEQILGKVSIAVIKGLTYL-------REKHKIMHRDVKPSNIL 197
            H +G   D +L +     E +   ++ + I GL +L       R K  I HRD+K  NIL
Sbjct: 1307 HENGSLHDYLLSRVLDSSEML--ALAHSAICGLAHLHIEIFGTRGKPAIAHRDIKSKNIL 1134

Query: 198  VNSRGEIKLCDFGVSGQLI------DSMANSFVGTRSYMSPERLQ------GTHYSVQSD 245
            V   G   + D G++ + I      D   N   GT+ YM+PE L+            Q+D
Sbjct: 1133 VKKNGTCCIADLGLAVRYISESNEVDVAPNPRQGTKRYMAPEVLEMLLNVKNFDAFKQAD 954

Query: 246  IWSMGLSLVEMA 257
            +++ GL + E+A
Sbjct: 953  MYAFGLVMWEIA 918
>12672
          Length = 773

 Score = 46.2 bits (108), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 30/101 (29%), Positives = 54/101 (53%), Gaps = 9/101 (8%)
 Frame = +3

Query: 168 KVSIAVIKGLTYLREKHKIMHRDVKPSNILVNSRGEIKLCDFGV-------SGQLIDSMA 220
           K+      G+ YL +   + HRD+K +NIL++S    K+ DF          G+ + + A
Sbjct: 3   KIVKGTASGIQYLNDNGHV-HRDIKTANILLDSEYTAKVGDFATVVSAPSGEGKTVQN-A 176

Query: 221 NSFVGTRSYMSPERLQGTHYSVQS--DIWSMGLSLVEMAVG 259
           +  +GT +Y++PE +   H+ V +  D +S G+ L+E+  G
Sbjct: 177 SVVIGTAAYLAPEAI---HFDVSTKLDSYSFGVVLLEVITG 290
>18996
          Length = 491

 Score = 45.8 bits (107), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 32/96 (33%), Positives = 53/96 (55%), Gaps = 8/96 (8%)
 Frame = +2

Query: 187 MHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSF-VGTRS----YMSPERLQGTHYS 241
           +HRD+   NILV+ R  +K+ DFG++ Q  ++    + +  R     + SPE ++   +S
Sbjct: 2   IHRDLAARNILVD-RSCVKISDFGLA-QFANADGYYYGISQRDIPIKWYSPEAIETCKFS 175

Query: 242 VQSDIWSMGLSLVEM-AVGRYP--IPPPDAKELELL 274
             SD+WS G++L EM + G  P  +P  D  + E L
Sbjct: 176 SYSDVWSYGVTLFEMFSRGEIPNLLPGHDLTQEEFL 283
>26711
          Length = 405

 Score = 45.1 bits (105), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 31/101 (30%), Positives = 51/101 (50%), Gaps = 7/101 (6%)
 Frame = -2

Query: 177 LTYLREKHK--IMHRDVKPSNILV--NSRGEIKLCDFGVSGQLI---DSMANSFVGTRSY 229
           L  L+  H   ++H D+KPSN+L+  +    ++L DFG++ +L    ++  N   GT  +
Sbjct: 386 LDILQHVHAQGVVHMDLKPSNLLLSGDKLDSVQLIDFGLARKLYPPQETFLNH--GTPGF 213

Query: 230 MSPERLQGTHYSVQSDIWSMGLSLVEMAVGRYPIPPPDAKE 270
            SPE L     S  SD+W +G+    +  G+ P     A E
Sbjct: 212 TSPEALDVKPISTASDVWGVGVLAYILLSGQSPFQADSATE 90
>18663
          Length = 600

 Score = 44.7 bits (104), Expect = 7e-05,   Method: Compositional matrix adjust.
 Identities = 18/43 (41%), Positives = 27/43 (62%)
 Frame = +2

Query: 221 NSFVGTRSYMSPERLQGTHYSVQSDIWSMGLSLVEMAVGRYPI 263
           ++F GT +Y++PE L+G  Y    D W++G+ L EM  GR P 
Sbjct: 2   STFCGTPNYIAPEILRGEDYGFSVDWWALGVLLYEMLAGRSPF 130
>17300
          Length = 480

 Score = 42.7 bits (99), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 25/83 (30%), Positives = 41/83 (49%), Gaps = 7/83 (8%)
 Frame = +1

Query: 187 MHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRS------YMSPERLQGTHY 240
           +HRD+   NILVN     K+ DFG+S ++          T+       + +PE +    +
Sbjct: 40  VHRDLAARNILVNEILVCKVADFGLSREIESDTTEGAYTTKGGKIPVRWTAPEAIAYRKF 219

Query: 241 SVQSDIWSMGLSLVE-MAVGRYP 262
           +  SD+WS G+ + E M+ G  P
Sbjct: 220 TSASDVWSFGVVMWEVMSYGERP 288
>02638
          Length = 1490

 Score = 42.4 bits (98), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 20/54 (37%), Positives = 31/54 (57%), Gaps = 1/54 (1%)
 Frame = +1

Query: 223 FVGTRSYMSPERLQGTHYSVQSDIWSMGLSLVEMAVGRYPIPPPD-AKELELLF 275
            +GT ++M+PE L+G  Y    D+WS+G  ++EM   R P    D +  L L+F
Sbjct: 16  LLGTIAFMAPEVLRGESYGRACDVWSVGCVMIEMCTCRPPWNSHDISNHLALIF 177
>11780
          Length = 1713

 Score = 42.4 bits (98), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 36/148 (24%), Positives = 68/148 (45%), Gaps = 2/148 (1%)
 Frame = +3

Query: 67  DFEKISELGAGNGGVVFKVSHKPSGLVMARKLIHLEIKPAIRNQIIRELQVLHECNSPYI 126
           D E    +G G+ G V+K  ++   + + +    L+ K       ++E  V+       +
Sbjct: 600 DLEIGEAIGKGDFGDVYKGMYRGQPVAIKQ----LKDKDRGEQSFLQEASVMTSLRHDNL 767

Query: 127 VGFYGAFYSDGEISICMEHMDGGSLDQVLKKAGR--IPEQILGKVSIAVIKGLTYLREKH 184
           V   G    +  I +  E M  G+L + L+  GR  I ++     +      + YL E  
Sbjct: 768 VRLIGVVLGE-TIFLVTEFMGKGNLVEYLRSRGRSVITKKDQINFATDTCAAMEYL-ESK 941

Query: 185 KIMHRDVKPSNILVNSRGEIKLCDFGVS 212
           +++HRD+   N+LV+  G+ K+ DFG++
Sbjct: 942 RLVHRDLAARNVLVHDDGKAKVSDFGLA 1025
>26156
          Length = 479

 Score = 42.0 bits (97), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 27/101 (26%), Positives = 50/101 (49%), Gaps = 3/101 (2%)
 Frame = -1

Query: 67  DFEKISELGAGNGGVVFKVSHKPSGLVMARKLIHLEIKPAIRN--QIIRELQVLHEC-NS 123
           DF  +  +G G+   V +V HK +  + A K+I  E+     +   +  E  V     N 
Sbjct: 386 DFLLLRVIGRGSYAKVLQVEHKRTKRIYAMKVIKKELVNDDEDIDWVQTEKHVFETATNY 207

Query: 124 PYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKKAGRIPEQ 164
           P++VG +  F S+  +   +E ++GG L   +++  R+PE+
Sbjct: 206 PFLVGLHSCFQSESRLFFVIEFVNGGDLMFHMQRQRRLPEE 84
>17637
          Length = 447

 Score = 41.2 bits (95), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 27/84 (32%), Positives = 43/84 (51%), Gaps = 6/84 (7%)
 Frame = +1

Query: 195 NILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSY-----MSPERLQGTHYSVQSDIWSM 249
           N +++ +  +KL D  +S  L     N  +G   Y     +S E LQ +HY+  SD+WS 
Sbjct: 1   NCVIDDQLRVKLTDSALSRDLFSGDYNC-LGDGEYRPIKWLSLEALQKSHYNEGSDVWSF 177

Query: 250 GLSLVEMA-VGRYPIPPPDAKELE 272
           G+ + EM  +G+ P    D  E+E
Sbjct: 178 GVLMWEMCTLGKLPYAEIDPYEME 249
>20640
          Length = 1492

 Score = 37.7 bits (86), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 22/76 (28%), Positives = 38/76 (50%), Gaps = 6/76 (7%)
 Frame = +1

Query: 187 MHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTR------SYMSPERLQGTHY 240
           +HRD+   N LV     +K+ DFG++  +     + + G+        +M  E +    +
Sbjct: 10  VHRDLATRNCLVGHDLVVKISDFGLARSV--HSVDYYRGSEHDAIPIRWMPLEAILYNKF 183

Query: 241 SVQSDIWSMGLSLVEM 256
           S QSD+WS G+ L E+
Sbjct: 184 STQSDVWSFGVVLWEI 231
>32000
          Length = 644

 Score = 37.4 bits (85), Expect = 0.011,   Method: Compositional matrix adjust.
 Identities = 25/67 (37%), Positives = 34/67 (50%), Gaps = 4/67 (5%)
 Frame = -1

Query: 202 GEIKLCDFG---VSGQLIDSMANSFVGTRSYMSPERLQGTH-YSVQSDIWSMGLSLVEMA 257
            ++K+ DFG   V G  + +  +  + T  Y +PE L G   YSV  DIWS+G   VEM 
Sbjct: 578 AKMKIADFGLARVFGLPVRTYTHEVI-TLWYRAPEILLGCRFYSVPVDIWSLGCIFVEMM 402

Query: 258 VGRYPIP 264
             R   P
Sbjct: 401 TRRALFP 381
>00486
          Length = 797

 Score = 35.4 bits (80), Expect = 0.038,   Method: Compositional matrix adjust.
 Identities = 17/52 (32%), Positives = 27/52 (51%)
 Frame = -2

Query: 219 MANSFVGTRSYMSPERLQGTHYSVQSDIWSMGLSLVEMAVGRYPIPPPDAKE 270
           + ++F GT  YM+PE L  T +    D WS+G  + +M  G  P    + K+
Sbjct: 790 VTHTFCGTIEYMAPEILTRTGHGKAVDWWSLGALMYDMLTGSPPFTAENRKK 635
>32957
          Length = 645

 Score = 35.4 bits (80), Expect = 0.040,   Method: Compositional matrix adjust.
 Identities = 14/37 (37%), Positives = 21/37 (56%)
 Frame = +3

Query: 220 ANSFVGTRSYMSPERLQGTHYSVQSDIWSMGLSLVEM 256
             +F GTR YM+PE  +   Y  + D W +G+ L E+
Sbjct: 36  TRTFCGTREYMAPEVHERKEYGKEVDWWGLGILLHEL 146
>20559
          Length = 430

 Score = 35.0 bits (79), Expect = 0.055,   Method: Compositional matrix adjust.
 Identities = 18/75 (24%), Positives = 41/75 (54%), Gaps = 1/75 (1%)
 Frame = -2

Query: 68  FEKISELGAGNGGVVFKVSHKPSGLVMARKLIHL-EIKPAIRNQIIRELQVLHECNSPYI 126
           +EK+ ++G G  G VFK  ++ +  ++A K + L +    + +  +RE+ +L E     I
Sbjct: 369 YEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKHRNI 190

Query: 127 VGFYGAFYSDGEISI 141
           V  +   +S+ ++++
Sbjct: 189 VRLHDVLHSERKLTL 145
>01106
          Length = 878

 Score = 34.7 bits (78), Expect = 0.060,   Method: Compositional matrix adjust.
 Identities = 13/26 (50%), Positives = 21/26 (80%)
 Frame = +3

Query: 173 VIKGLTYLREKHKIMHRDVKPSNILV 198
           V++GL+Y+  K +I+H D+KP NIL+
Sbjct: 672 VLEGLSYMHAKCRIIHTDIKPENILI 749
>38560
          Length = 479

 Score = 34.7 bits (78), Expect = 0.061,   Method: Compositional matrix adjust.
 Identities = 16/49 (32%), Positives = 26/49 (53%), Gaps = 1/49 (2%)
 Frame = -3

Query: 216 IDSMANSFVGTRSYMSPERLQGTHY-SVQSDIWSMGLSLVEMAVGRYPI 263
           +D    +  G+ +Y +PE + G  Y   ++DIWSMG+ L  +  G  P 
Sbjct: 426 MDHHLTTCCGSPAYAAPELISGLEYLGSEADIWSMGVLLYALLCGYLPF 280
>21800
          Length = 855

 Score = 34.3 bits (77), Expect = 0.085,   Method: Compositional matrix adjust.
 Identities = 14/26 (53%), Positives = 19/26 (73%)
 Frame = +2

Query: 173 VIKGLTYLREKHKIMHRDVKPSNILV 198
           V++GL YL  K  I+H D+KP NIL+
Sbjct: 659 VLEGLNYLHAKCNIIHTDIKPENILI 736
>16708
          Length = 1397

 Score = 34.3 bits (77), Expect = 0.089,   Method: Compositional matrix adjust.
 Identities = 24/97 (24%), Positives = 45/97 (46%), Gaps = 9/97 (9%)
 Frame = -1

Query: 125  YIVGFYGAFYSD---GEISICMEHMDGGSLDQVLK--KAGRIPEQILGKVSIAVIKGLTY 179
            Y+   +GA+ +     +++I +   + G L  V    K   +P +      +  I G   
Sbjct: 1241 YLAQMFGAWVTCLPFPKMNILLHFYEMGPLCNVYAHYKNKEMPIRWSNPAMVCCIAGQXV 1062

Query: 180  LREKH----KIMHRDVKPSNILVNSRGEIKLCDFGVS 212
               +H     ++H DVK  N+LV++ G  KL D+G++
Sbjct: 1061 CALEHIHELGVVHMDVKADNVLVDAHGNCKLTDYGIA 951
>13305
          Length = 549

 Score = 33.9 bits (76), Expect = 0.10,   Method: Compositional matrix adjust.
 Identities = 16/44 (36%), Positives = 25/44 (56%), Gaps = 1/44 (2%)
 Frame = +2

Query: 229 YMSPERLQGTHYSVQSDIWSMGLSLVEM-AVGRYPIPPPDAKEL 271
           +M+ E L    Y+ QSD+WS G+ L E+  +G  P    D ++L
Sbjct: 23  WMAVESLFNNTYTTQSDVWSFGVVLWEIFTLGGTPYSSTDTQQL 154
>29590
          Length = 320

 Score = 33.1 bits (74), Expect = 0.22,   Method: Composition-based stats.
 Identities = 12/28 (42%), Positives = 20/28 (71%)
 Frame = +3

Query: 224 VGTRSYMSPERLQGTHYSVQSDIWSMGL 251
           +GT  Y++PE L     S+Q+D+WS+G+
Sbjct: 57  IGTPDYVAPEVLDYEPLSIQTDMWSLGV 140
>18401
          Length = 463

 Score = 32.0 bits (71), Expect = 0.48,   Method: Compositional matrix adjust.
 Identities = 16/50 (32%), Positives = 25/50 (50%)
 Frame = -3

Query: 221 NSFVGTRSYMSPERLQGTHYSVQSDIWSMGLSLVEMAVGRYPIPPPDAKE 270
           ++ V TR Y +PE +    +S   D+WS+G  + E+  G       D KE
Sbjct: 458 STIVSTRHYRAPEVILELGWSHPCDVWSVGCIMFELYTGYTLFQTHDNKE 309
>31489
          Length = 329

 Score = 30.0 bits (66), Expect = 1.8,   Method: Composition-based stats.
 Identities = 11/25 (44%), Positives = 20/25 (80%)
 Frame = +3

Query: 173 VIKGLTYLREKHKIMHRDVKPSNIL 197
           +++GL Y+   + ++HRD+KPSN+L
Sbjct: 192 ILRGLKYIHSAN-VVHRDLKPSNLL 263
>15549
          Length = 470

 Score = 29.6 bits (65), Expect = 2.0,   Method: Compositional matrix adjust.
 Identities = 15/45 (33%), Positives = 24/45 (53%)
 Frame = -1

Query: 66  DDFEKISELGAGNGGVVFKVSHKPSGLVMARKLIHLEIKPAIRNQ 110
           D+FE I ++G G  G+VF+  +K      A K I L    A++ +
Sbjct: 218 DEFECIEQMGKGGYGIVFRAKNKVDEQEYAVKRIALPSDAAVKKR 84
>22501
          Length = 1197

 Score = 29.3 bits (64), Expect = 3.1,   Method: Compositional matrix adjust.
 Identities = 13/33 (39%), Positives = 23/33 (69%)
 Frame = -3

Query: 58  QKVGELKDDDFEKISELGAGNGGVVFKVSHKPS 90
           +K GE + + +E + ++G G G V+FK+ H+PS
Sbjct: 538 EKSGE-RGNVWEGLFQMGLGGGKVIFKILHRPS 443
>22098
          Length = 1090

 Score = 29.3 bits (64), Expect = 3.2,   Method: Compositional matrix adjust.
 Identities = 19/58 (32%), Positives = 29/58 (50%), Gaps = 14/58 (24%)
 Frame = +2

Query: 221 NSFVGTRSYMSPERLQGT-----HYSVQSDIWSMGLSLVEM---------AVGRYPIP 264
           +  VGTR YM+PE L+G         ++ D+++ GL L E+          VG Y +P
Sbjct: 8   HGLVGTRRYMAPEVLEGAICFNRDSFLRIDMYACGLVLWELMTRCNAAEGPVGEYQLP 181
>22005
          Length = 873

 Score = 28.9 bits (63), Expect = 3.4,   Method: Compositional matrix adjust.
 Identities = 23/94 (24%), Positives = 46/94 (48%), Gaps = 6/94 (6%)
 Frame = +1

Query: 169 VSIAVIKGLTYLREKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRS 228
           +S  +  G+ YL +K  + HRD+  +  + +      + DFG++  +     + + G+  
Sbjct: 457 ISQQISAGMAYLAQKDYV-HRDL-ATRTVXSRTT*S*ISDFGLARSV--HSVDYYRGSEQ 624

Query: 229 ------YMSPERLQGTHYSVQSDIWSMGLSLVEM 256
                 +M  E +  + +S QSD+WS G+ L E+
Sbjct: 625 DAIPIRWMPLEAILYSKFSTQSDVWSFGVVLWEI 726
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6753086|ref|NP_033817.1| APEX nuclease 1 [Mus
musculus]
         (317 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

14956                                                                 152   1e-37
11080                                                                  54   6e-08
10554                                                                  42   4e-04
05292                                                                  40   9e-04
08148                                                                  39   0.003
11563                                                                  37   0.014
31888                                                                  36   0.022
15133                                                                  33   0.15 
05625                                                                  33   0.19 
19367                                                                  32   0.24 
31391                                                                  32   0.47 
02209                                                                  30   1.4  
16021                                                                  29   2.5  
19436                                                                  28   4.9  
14117                                                                  28   5.3  
13282                                                                  27   8.6  
>14956
          Length = 1170

 Score =  152 bits (385), Expect = 1e-37,   Method: Compositional matrix adjust.
 Identities = 70/111 (63%), Positives = 85/111 (76%)
 Frame = +2

Query: 202 KPLVLCGDLNVAHEEIDLRNPKGNKKNAGFTPQERQGFGELLQAVPLADSFRHLYPNTAY 261
           +P+VLCGDLNVAH +IDL+NPKGNK+NAGFT +ER+GF +LL+     DSFR LYP+   
Sbjct: 44  EPVVLCGDLNVAHLDIDLKNPKGNKRNAGFTTEEREGFXKLLEE-GFIDSFRTLYPDKEE 220

Query: 262 AYTFWTYMMNARSKNVGWRLDYFLLSHSLLPALCDSKIRSKALGSDHCPIT 312
           AYTFW+    AR KN+GWRLDYF+LS  L   LCDS IR+  +GSDHCPI 
Sbjct: 221 AYTFWSNFRQAREKNIGWRLDYFVLSQRLKKDLCDSLIRTHVMGSDHCPIV 373
>11080
          Length = 1275

 Score = 54.3 bits (129), Expect = 6e-08,   Method: Compositional matrix adjust.
 Identities = 72/268 (26%), Positives = 120/268 (44%), Gaps = 12/268 (4%)
 Frame = -3

Query: 61  LKICSWNVDGLRAWIKKKGL-DWVKEEAPDILCLQETKCSENKLPAELQELPGLTHQYWS 119
           L I + NV GL+  +K+  + ++ +++  DI+CLQET  +E K  A  ++  G    Y S
Sbjct: 997 LNIITLNVRGLKNKLKRNAMFNFFRQQKLDIICLQETHITE-KESALWEKQWGGKLFYNS 821

Query: 120 APSDKEGYSGVGLLSRQCPLKVSYGIGEEEHDQE-GRVIVAEFES----FVLVTAYVPNA 174
             +  +G   V L+S+       Y  G+ +++Q   R++V   E+    F +V  Y PN 
Sbjct: 820 GTAHSKG--EVILISK-------YFNGKAKYEQSTDRILVISLETDDSLFTIVNTYSPNN 668

Query: 175 GRGLVRLEYRQRWDEAFRKFLKDLASR---KPLVLCGDLN-VAHEEIDLR--NPKGNKKN 228
           G+  +          AF K L+   ++   K L+L GD N V   E D+   NP   K  
Sbjct: 667 GQDKI----------AFFKKLQTFLTQYMSKILILVGDFNSVMCNESDIISGNPHCQK-- 524

Query: 229 AGFTPQERQGFGELLQAVPLADSFRHLYPNTAYAYTFWTYMMNARSKNVGWRLDYFLLSH 288
                 E     + L ++ L D +RH + N    YT W+     ++  +  R+DY   + 
Sbjct: 523 ------EIDQLNKTLNSLGLKDLWRHXH-NEEKEYT-WS----RQNPFIARRIDYCFANK 380

Query: 289 SLLPALCDSKIRSKALGSDHCPITLYLA 316
            +    C   I S A  SDH  + + + 
Sbjct: 379 EVEMKCCSCNIVSVA-NSDHRAVVMEIT 299
>10554
          Length = 1502

 Score = 41.6 bits (96), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 69/273 (25%), Positives = 108/273 (39%), Gaps = 15/273 (5%)
 Frame = +2

Query: 60  TLKICSWNVDGLRAWIKKKGL-DWVKEEAPDILCLQETKCSENKLPAELQELPGLTHQYW 118
           +++I S N  GL    K++ +  ++K++   I CLQ+T   + +L   +    G    + 
Sbjct: 551 SIRIASLNCQGLGDMRKRRDVFHYLKQKDCSIYCLQDTHF-DKRLEKYVNSEWGYKCFFA 727

Query: 119 SAPSDKEGYSGVGLLSRQCPLKVSYGIGEEEHDQEGRVIVAEFES----FVLVTAYVPNA 174
           S  S+  G +   L S     K    I + + D+ G  I   F S     +LV  Y PN 
Sbjct: 728 SYRSNSRGVAV--LFSNNFEFK----IQDVKIDKNGNFIFVSFSSMDKDILLVNVYGPNK 889

Query: 175 GRGLVRLEYRQRWDEAFRKFLKDLA---SRKPLVLCGDLNVAHE-EID------LRNPKG 224
                        D  F   LK++    +   ++  GD N+A +  ID      + NPK 
Sbjct: 890 D------------DPVFYDNLKEIIKSYNNNNIIAVGDWNIAMDPNIDCDGYLHVNNPKA 1033

Query: 225 NKKNAGFTPQERQGFGELLQAVPLADSFRHLYPNTAYAYTFWTYMMNARSKNVGWRLDYF 284
                      R+    + + + LAD +R   P+ +  YT W      +      RLDYF
Sbjct: 1034-----------REVLQNMTEELGLADIWRESNPSVS-RYT-WRKPTPLKQS----RLDYF 1162

Query: 285 LLSHSLLPALCDSKIRSKALGSDHCPITLYLAL 317
           LLS  L      + I      SDH  +TL L  
Sbjct: 1163LLSDYLYSYFESTDILP-GYRSDHSIVTLNLKF 1258
>05292
          Length = 2397

 Score = 40.4 bits (93), Expect = 9e-04,   Method: Compositional matrix adjust.
 Identities = 62/266 (23%), Positives = 111/266 (41%), Gaps = 9/266 (3%)
 Frame = +1

Query: 57   KSATLKICSWNVDGLRAWIKKKGL-DWVKEEAPDILCLQETKCSENKLPAELQELPGLTH 115
            K  +++I S+NV+G+  + K+K + D+++++   I+ LQET     +  A ++ + G   
Sbjct: 820  KMDSIQILSFNVNGIGDYHKRKDVFDYLRKQKAQIIFLQETHLKTQQENA-VRSMWGYEC 996

Query: 116  QYWSAPSDKEGYSGVGLLSRQCPLKVSYGIGEEEHDQEGRVIVAEFE----SFVLVTAYV 171
                A ++ +G   VG+          Y + +     EG  I+ + E       LV  Y 
Sbjct: 997  ILSGADTNSKG---VGIFFNN---DFGYKVHKIIRGDEGNYIILDIEFLNKRMTLVNLYG 1158

Query: 172  PNAGRGLVRLEYRQRWD--EAFRKFLK--DLASRKPLVLCGDLNVAHEEIDLRNPKGNKK 227
            P+             WD    F       D    + +V+ GD NV    +D+ N    + 
Sbjct: 1159 PSG------------WDSPNFFNSIFMQIDNVGNENVVIGGDWNVI---LDV-NKDAFRY 1290

Query: 228  NAGFTPQERQGFGELLQAVPLADSFRHLYPNTAYAYTFWTYMMNARSKNVGWRLDYFLLS 287
                 P  R+   + ++   L D +R   P+    YT+  +  + +      RLDYFL+S
Sbjct: 1291 RFMNRPNSRRLLRDSMERYNLIDVWREFNPDKR-QYTWRRFNSSQQG-----RLDYFLIS 1452

Query: 288  HSLLPALCDSKIRSKALGSDHCPITL 313
              L+  +  + I+     SDH  I L
Sbjct: 1453 GHLMLDVKSTDIKP-GYRSDHNIIVL 1527
>08148
          Length = 1644

 Score = 38.9 bits (89), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 61/236 (25%), Positives = 93/236 (39%), Gaps = 8/236 (3%)
 Frame = +1

Query: 90  ILCLQETKCSENKLPAELQELPGLTHQYWSAPSDKEGYSGVGLLSRQCPLKVSYGIGEEE 149
           I CLQ+T  S +KL + ++   G T  + S  ++  G   V +L         + I +  
Sbjct: 451 IYCLQDTHFS-SKLESYVKSEWGYTSVFASFKTNSRG---VAILFSN---NFDFKIKKIT 609

Query: 150 HDQEGRVIVAEFES----FVLVTAYVPNAGRGLVRLEYRQRWDEAFRKFLKD---LASRK 202
            D+ G  ++  F +     +LV  Y PN              D +F   LK+   +    
Sbjct: 610 RDKSGNYLLISFSTMDTDLLLVNVYGPNKD------------DPSFYDSLKETIKMYKTN 753

Query: 203 PLVLCGDLNVAHE-EIDLRNPKGNKKNAGFTPQERQGFGELLQAVPLADSFRHLYPNTAY 261
            ++  GD N+A +  ID  N   N       P+ R     +   + LAD +R   P +  
Sbjct: 754 NVIAVGDWNIALDPNIDCFNYVHNN-----NPRARGALENMTLELNLADVWRESNPESR- 915

Query: 262 AYTFWTYMMNARSKNVGWRLDYFLLSHSLLPALCDSKIRSKALGSDHCPITLYLAL 317
            YT W      +      RLDYFLLS  L     ++ I      SDH  +TL L  
Sbjct: 916 RYT-WRRPTPLKQS----RLDYFLLSDYLYRYFENTDILP-GYRSDHSIVTLTLKF 1065
>11563
          Length = 501

 Score = 36.6 bits (83), Expect = 0.014,   Method: Compositional matrix adjust.
 Identities = 41/132 (31%), Positives = 57/132 (43%), Gaps = 4/132 (3%)
 Frame = +2

Query: 188 DEAFRKFLKDLA---SRKPLVLCGDLNVAHE-EIDLRNPKGNKKNAGFTPQERQGFGELL 243
           D  F   LKD A   + K ++  GD N+A + +ID  N   +       P+ R+    + 
Sbjct: 2   DPEFYNTLKDTAKSYNNKNIIAVGDWNIALDPKIDCHNYLHDN-----NPKAREALENMT 166

Query: 244 QAVPLADSFRHLYPNTAYAYTFWTYMMNARSKNVGWRLDYFLLSHSLLPALCDSKIRSKA 303
             + LAD +R   P T+  YT W      +      RLDYFLLS  L     +  I    
Sbjct: 167 IELDLADXWRENNP-TSRCYT-WRKTNPLKQS----RLDYFLLSDYLFSYFENVDILP-G 325

Query: 304 LGSDHCPITLYL 315
             SDH  +TL L
Sbjct: 326 YRSDHSIVTLSL 361
>31888
          Length = 332

 Score = 35.8 bits (81), Expect = 0.022,   Method: Compositional matrix adjust.
 Identities = 16/41 (39%), Positives = 28/41 (68%), Gaps = 1/41 (2%)
 Frame = +3

Query: 61  LKICSWNVDGLRAWIKKKGL-DWVKEEAPDILCLQETKCSE 100
           ++I S NV GL+  +K+  L ++ K++  DI+CLQET  ++
Sbjct: 162 IRILSLNVRGLKNRLKRSVLFNYFKQQKIDIICLQETHITD 284
>15133
          Length = 1187

 Score = 33.1 bits (74), Expect = 0.15,   Method: Compositional matrix adjust.
 Identities = 26/83 (31%), Positives = 40/83 (48%)
 Frame = -3

Query: 233 PQERQGFGELLQAVPLADSFRHLYPNTAYAYTFWTYMMNARSKNVGWRLDYFLLSHSLLP 292
           P  R+   ++++A  L D +R   P    +YT+  +    +      RLDYFLLS  L+ 
Sbjct: 453 PHARKTLFDIMEAHNLVDVWREQNPEKR-SYTWRRFNTTQQG-----RLDYFLLSDHLML 292

Query: 293 ALCDSKIRSKALGSDHCPITLYL 315
               + I++    SDH  ITL L
Sbjct: 291 DTKKANIKA-GYRSDHSIITLEL 226
>05625
          Length = 2289

 Score = 32.7 bits (73), Expect = 0.19,   Method: Compositional matrix adjust.
 Identities = 32/117 (27%), Positives = 53/117 (45%)
 Frame = -3

Query: 197  DLASRKPLVLCGDLNVAHEEIDLRNPKGNKKNAGFTPQERQGFGELLQAVPLADSFRHLY 256
            D  +   +V+ GD NV    +D+ N    +  +   P+ RQ    ++    L D +R   
Sbjct: 1630 DDINNDNIVIGGDWNVI---LDI-NKDAFRYRSSNRPRARQMLCNIVDTYNLVDVWRAHN 1463

Query: 257  PNTAYAYTFWTYMMNARSKNVGWRLDYFLLSHSLLPALCDSKIRSKALGSDHCPITL 313
            P+    YT+  +    +      RLDYFL+S  L+  + ++ I S    SDH  I+L
Sbjct: 1462 PDKR-QYTWRRFNSTQQG-----RLDYFLISEHLMLDIKNANITS-GYRSDHNIISL 1313
>19367
          Length = 401

 Score = 32.3 bits (72), Expect = 0.24,   Method: Compositional matrix adjust.
 Identities = 15/30 (50%), Positives = 18/30 (60%)
 Frame = -3

Query: 286 LSHSLLPALCDSKIRSKALGSDHCPITLYL 315
           L  S +  +CD  I   +LGSDH PITL L
Sbjct: 363 LVSSDIAVMCDWVINDDSLGSDHLPITLTL 274
>31391
          Length = 480

 Score = 31.6 bits (70), Expect = 0.47,   Method: Compositional matrix adjust.
 Identities = 18/38 (47%), Positives = 21/38 (55%)
 Frame = +2

Query: 280 RLDYFLLSHSLLPALCDSKIRSKALGSDHCPITLYLAL 317
           RLD+FLLS  L+   CDS I      SDH  +TL L  
Sbjct: 53  RLDFFLLSDYLMWLYCDSDI-IPGYRSDHSIVTLTLQF 163
>02209
          Length = 1546

 Score = 30.0 bits (66), Expect = 1.4,   Method: Compositional matrix adjust.
 Identities = 41/156 (26%), Positives = 65/156 (41%)
 Frame = -3

Query: 162 ESFVLVTAYVPNAGRGLVRLEYRQRWDEAFRKFLKDLASRKPLVLCGDLNVAHEEIDLRN 221
           + F+LV  Y PN        E+ Q      +  L  L  R  +++ GD N+    +D   
Sbjct: 704 KDFLLVNVYGPNRDEP----EFYQ----TIKNLLVGLECRN-IIMAGDFNLV---MDPSR 561

Query: 222 PKGNKKNAGFTPQERQGFGELLQAVPLADSFRHLYPNTAYAYTFWTYMMNARSKNVGWRL 281
              N K+    P+ ++     +  + L D +R + P+    YT+       +S     RL
Sbjct: 560 DYDNYKHIN-NPKAKEVIERTINELDLNDIWRDMNPDCQ-RYTWRRANPFQQS-----RL 402

Query: 282 DYFLLSHSLLPALCDSKIRSKALGSDHCPITLYLAL 317
           D FL+S S+L  + D+ I      SDH  I L L  
Sbjct: 401 DXFLVSDSILDYVEDTDILC-GYRSDHSMILLKLKF 297
>16021
          Length = 509

 Score = 29.3 bits (64), Expect = 2.5,   Method: Compositional matrix adjust.
 Identities = 19/59 (32%), Positives = 24/59 (40%)
 Frame = +2

Query: 79  GLDWVKEEAPDILCLQETKCSENKLPAELQELPGLTHQYWSAPSDKEGYSGVGLLSRQC 137
            L WV    P  L L   KCS+NK  A+L  +     + W  P +         LS QC
Sbjct: 113 SLTWVTLTRPISLALCYMKCSDNKSVAKLYMITDAKSRCWGIPHE------CSFLSNQC 271
>19436
          Length = 380

 Score = 28.1 bits (61), Expect = 4.9,   Method: Compositional matrix adjust.
 Identities = 16/46 (34%), Positives = 20/46 (43%)
 Frame = +2

Query: 112 GLTHQYWSAPSDKEGYSGVGLLSRQCPLKVSYGIGEEEHDQEGRVI 157
           GLT   W  PS+  GY G+      C L       EE +D+   VI
Sbjct: 14  GLT---WEFPSESAGYQGITFWKFNCSLLRDQNYVEEINDEIDNVI 142
>14117
          Length = 1117

 Score = 28.1 bits (61), Expect = 5.3,   Method: Compositional matrix adjust.
 Identities = 19/52 (36%), Positives = 24/52 (46%), Gaps = 1/52 (1%)
 Frame = +3

Query: 259 TAYAYTFWTYMMNARSKNVGWRLDYFLLSH-SLLPALCDSKIRSKALGSDHC 309
           TA    FWT + +    +V W     LLSH SL P  C +  +   LG  HC
Sbjct: 873 TALEQVFWTALTSPSILDVTWI*TXRLLSHCSLYPVCCAAHYKHLVLGC-HC 1025
>13282
          Length = 817

 Score = 27.3 bits (59), Expect = 8.6,   Method: Compositional matrix adjust.
 Identities = 12/34 (35%), Positives = 17/34 (50%)
 Frame = +1

Query: 282 DYFLLSHSLLPALCDSKIRSKALGSDHCPITLYL 315
           DY + SH +   +   K+      SDHCPI L +
Sbjct: 241 DYCICSHDIRKDVISMKVHPLTEFSDHCPIELMV 342
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|71725385|ref|NP_001019645.1| DIRAS family,
GTP-binding RAS-like 2 [Mus musculus]
         (199 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

07580                                                                 136   1e-37
00858                                                                  94   3e-20
08428                                                                  86   7e-18
33374                                                                  56   7e-14
34468                                                                  71   3e-13
06994                                                                  52   7e-13
19006                                                                  68   2e-12
11728                                                                  67   5e-12
36482                                                                  67   7e-12
26536                                                                  66   1e-11
14456                                                                  62   2e-10
19656                                                                  58   2e-09
01398                                                                  54   4e-08
33794                                                                  53   1e-07
32723                                                                  52   1e-07
31291                                                                  50   5e-07
34597                                                                  49   9e-07
01972                                                                  45   2e-05
01095                                                                  44   6e-05
29380                                                                  43   8e-05
33380                                                                  42   1e-04
34359                                                                  39   0.001
09204                                                                  37   0.005
00552                                                                  31   0.32 
10708                                                                  31   0.33 
00780                                                                  31   0.38 
11378                                                                  28   2.7  
18949                                                                  27   4.1  
27191                                                                  27   7.3  
>07580
          Length = 921

 Score =  136 bits (343), Expect(2) = 1e-37,   Method: Compositional matrix adjust.
 Identities = 62/138 (44%), Positives = 90/138 (65%)
 Frame = +3

Query: 29  KGTFRESYIPTVEDTYRQVISCDKSICTLQITDTTGSHQFPAMQRLSISKGHAFILVYSI 88
           KG F E Y PT+ED+YR+ +  D   C L+I DT G+ QF AM+ L +  G  F+L YSI
Sbjct: 126 KGIFVEKYDPTIEDSYRKQVEVDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFLLAYSI 305

Query: 89  TSRQSLEELKPIYEQICEIKGDVESIPIMLVGNKCDESPNREVQSSEAEALARTWKCAFM 148
           T++ +  +L+ + EQI  +K D + +P++LVGNKCD    R V   + + LAR++ CAF+
Sbjct: 306 TAQSTFNDLQELREQILRVK-DTDDVPMLLVGNKCDLEDERVVGKDQGQGLARSFSCAFL 482

Query: 149 ETSAKLNHNVKELFQELL 166
           ETSAK   NV E+F +L+
Sbjct: 483 ETSAKARINVNEIFMDLV 536

 Score = 36.2 bits (82), Expect(2) = 1e-37,   Method: Compositional matrix adjust.
 Identities = 15/30 (50%), Positives = 23/30 (76%)
 Frame = +2

Query: 3  EQSNDYRVAVFGAGGVGKSSLVLRFVKGTF 32
          E   +Y++ V G+GGVGKS+L ++FV+G F
Sbjct: 47 ETMREYKLVVLGSGGVGKSALTVQFVQGDF 136
>00858
          Length = 1658

 Score = 94.4 bits (233), Expect = 3e-20,   Method: Compositional matrix adjust.
 Identities = 58/163 (35%), Positives = 93/163 (57%)
 Frame = -2

Query: 4    QSNDYRVAVFGAGGVGKSSLVLRFVKGTFRESYIPTVEDTYRQVISCDKSICTLQITDTT 63
            Q  +Y++ V GAGGVGKS+L ++  +  F E Y PT ED+ R+ +  D   C L I DT 
Sbjct: 1600 QMTEYKLVVVGAGGVGKSALTIQLXQNHFVEEYDPTXEDSXRKQVVIDGETCLLDILDTA 1421

Query: 64   GSHQFPAMQRLSISKGHAFILVYSITSRQSLEELKPIYEQICEIKGDVESIPIMLVGNKC 123
            G  +  AM+   +  G  F+ V+++ + +S E++    EQI  +K D + +P++LVGNK 
Sbjct: 1420 GQEEXSAMRDQCMRTGEGFLCVFAVXNLKSFEDINQYREQIKRVK-DADEVPMVLVGNKV 1244

Query: 124  DESPNREVQSSEAEALARTWKCAFMETSAKLNHNVKELFQELL 166
            D  P R V+  + + +A  +   ++ETSAK    V + F  L+
Sbjct: 1243 D-LPIRNVEQRQGKHMAELYHIPYVETSAKTRQGVDDAFYTLV 1118
>08428
          Length = 1109

 Score = 86.3 bits (212), Expect = 7e-18,   Method: Compositional matrix adjust.
 Identities = 55/166 (33%), Positives = 87/166 (52%), Gaps = 1/166 (0%)
 Frame = -3

Query: 1    MPEQSNDYRVAVFGAGGVGKSSLVLRFVKGTFRESYIPTVEDTY-RQVISCDKSICTLQI 59
            M  Q  D +V + G  GVGKSS+VLRFV G++R S   T+  ++  + +  D +    QI
Sbjct: 1089 MRMQMRDVKVCLLGDSGVGKSSIVLRFVTGSYRPSQESTIGASFMSKSLVVDGAGYRFQI 910

Query: 60   TDTTGSHQFPAMQRLSISKGHAFILVYSITSRQSLEELKPIYEQICEIKGDVESIPIMLV 119
             DT G  +F A+  +      A ++VY +T  ++ + +K   +++        +I + + 
Sbjct: 909  WDTAGQEKFRALAPMYYRGAAAAVIVYDVTRPRTFKSVKSWIQELRSF--GPPNIVLAIA 736

Query: 120  GNKCDESPNREVQSSEAEALARTWKCAFMETSAKLNHNVKELFQEL 165
            GNKCD    REV   +A+  A +    F ETSA    NV+E+F EL
Sbjct: 735  GNKCDLEELREVVEKDAQEYASSISAIFGETSAMTAVNVEEMFTEL 598
>33374
          Length = 489

 Score = 56.2 bits (134), Expect(2) = 7e-14,   Method: Compositional matrix adjust.
 Identities = 35/116 (30%), Positives = 57/116 (49%)
 Frame = +1

Query: 46  QVISCDKSICTLQITDTTGSHQFPAMQRLSISKGHAFILVYSITSRQSLEELKPIYEQIC 105
           Q +  D +    +I DT G  ++ ++  +      A I+VY IT++ +    K   +++ 
Sbjct: 148 QTVCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNQDTFGRAKTWVKELQ 327

Query: 106 EIKGDVESIPIMLVGNKCDESPNREVQSSEAEALARTWKCAFMETSAKLNHNVKEL 161
             +    +I I L GNK D +  R V+  EA+A A      FMETSAK   NV ++
Sbjct: 328 --RQASPNIVIALAGNKADLANKRMVEFEEAQAYAEENSLLFMETSAKTAMNVNDI 489

 Score = 37.4 bits (85), Expect(2) = 7e-14,   Method: Compositional matrix adjust.
 Identities = 19/44 (43%), Positives = 26/44 (59%), Gaps = 2/44 (4%)
 Frame = +2

Query: 7  DYRVAVFGAGGVGKSSLVLRFVKGTFRESYIPTVEDTY--RQVI 48
           +++ + G   VGKSSLVLRFVKG F E    T+   +  RQ +
Sbjct: 29 QFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAF*LRQFV 160
>34468
          Length = 1502

 Score = 71.2 bits (173), Expect = 3e-13,   Method: Compositional matrix adjust.
 Identities = 48/152 (31%), Positives = 71/152 (46%), Gaps = 2/152 (1%)
 Frame = +1

Query: 4   QSNDYRVAVFGAGGVGKSSLVLRFVKGTFRESYIPTVEDTYRQ-VISCDKSICTLQITDT 62
           Q   +++ V G   VGK+ L  RF  G F +    T+   +R+  I  D     LQ+ DT
Sbjct: 484 QRRIFKIIVIGDSNVGKTCLTYRFCLGKFPDKTEATIGVDFREKSIQVDSEHLKLQLWDT 663

Query: 63  TGSHQF-PAMQRLSISKGHAFILVYSITSRQSLEELKPIYEQICEIKGDVESIPIMLVGN 121
            G  +F  +M +      HA + VY +T   S E + P + + C+     + IP +LVGN
Sbjct: 664 AGQERFRKSMVQHYYRNVHAVVFVYDMTKMSSFENM-PAWIEECDRHNLTKYIPRILVGN 840

Query: 122 KCDESPNREVQSSEAEALARTWKCAFMETSAK 153
           KCD      V ++ A+  A        ETSAK
Sbjct: 841 KCDVVERIAVNTNLAQKFADAHNMPLFETSAK 936
>06994
          Length = 429

 Score = 52.0 bits (123), Expect(2) = 7e-13,   Method: Compositional matrix adjust.
 Identities = 31/102 (30%), Positives = 45/102 (44%), Gaps = 32/102 (31%)
 Frame = +1

Query: 29  KGTFRESYIPTVEDTYRQVISCDKSICTLQITDTTG----SH------------------ 66
           KG   + Y PT+ED+YR+ +  D   C L+I DT G    SH                  
Sbjct: 121 KGFLWKKYDPTIEDSYRKQVEVDGQQCMLEILDTAGTVHASHSNACVHGSLHAFVGTVTP 300

Query: 67  ----------QFPAMQRLSISKGHAFILVYSITSRQSLEELK 98
                     QF AM+ L +  G  F+L YSIT++ +  +L+
Sbjct: 301 LGRDALLNTEQFTAMRDLYMKNGQGFLLAYSITAQSTFNDLQ 426

 Score = 38.1 bits (87), Expect(2) = 7e-13,   Method: Compositional matrix adjust.
 Identities = 16/32 (50%), Positives = 24/32 (75%)
 Frame = +3

Query: 3  EQSNDYRVAVFGAGGVGKSSLVLRFVKGTFRE 34
          E   +Y++ V G+GGVGKS+L ++FV+G F E
Sbjct: 42 ETMREYKLVVLGSGGVGKSALTVQFVQGIFVE 137
>19006
          Length = 568

 Score = 68.2 bits (165), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 41/135 (30%), Positives = 67/135 (49%), Gaps = 4/135 (2%)
 Frame = -2

Query: 9   RVAVFGAGGVGKSSLVLRFVKGTFRESYIPTVEDTYRQVISCDKSICTLQITDTTGSHQF 68
           ++ + G G  GK+ L++ F K  F E Y+PTV + Y   I  D     L + DT G   +
Sbjct: 432 KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDSKQVELALWDTAGQEDY 253

Query: 69  PAMQRLSISKGHAFILVYSITSRQSLEELKPIYEQICEIKGDVESIPIMLVGNK----CD 124
             ++ LS       ++ +SI S  SLE +   +    E++    ++PI+LVGNK     D
Sbjct: 252 DRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTP--EVRHFCPNVPIILVGNKKDLRND 79

Query: 125 ESPNREVQSSEAEAL 139
           E+  RE+   + E +
Sbjct: 78  ENTKRELMKMKQEPV 34
>11728
          Length = 635

 Score = 67.0 bits (162), Expect = 5e-12,   Method: Compositional matrix adjust.
 Identities = 37/122 (30%), Positives = 59/122 (48%)
 Frame = -1

Query: 9   RVAVFGAGGVGKSSLVLRFVKGTFRESYIPTVEDTYRQVISCDKSICTLQITDTTGSHQF 68
           +  V G G VGK+ L++ +    F   YIPTV D Y   +  D     L + DT G   +
Sbjct: 485 KCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDSKPINLGLWDTAGQEDY 306

Query: 69  PAMQRLSISKGHAFILVYSITSRQSLEELKPIYEQICEIKGDVESIPIMLVGNKCDESPN 128
             ++ LS  +   F++ +S+ S  S E +K  +    E+     + PI+LVG K D   +
Sbjct: 305 DRLRPLSYPQTDVFLICFSLISPASFENVKAKWYP--EVSHHCPNTPIILVGTKLDLRED 132

Query: 129 RE 130
           +E
Sbjct: 131 KE 126
>36482
          Length = 686

 Score = 66.6 bits (161), Expect = 7e-12,   Method: Compositional matrix adjust.
 Identities = 42/130 (32%), Positives = 61/130 (46%)
 Frame = +2

Query: 23  LVLRFVKGTFRESYIPTVEDTYRQVISCDKSICTLQITDTTGSHQFPAMQRLSISKGHAF 82
           L +RF+   F   Y PT+E  Y+     +     L+I DT G   +P  +  ++     F
Sbjct: 2   LTVRFLTRRFIGEYCPTLESVYKYHTVIEDDDVRLEILDTAGQGTYPWKEGYALW-ADCF 178

Query: 83  ILVYSITSRQSLEELKPIYEQICEIKGDVESIPIMLVGNKCDESPNREVQSSEAEALART 142
           + VYSI  RQS EEL  +  Q+  ++    S+  +L  NK D   +R+V   E E LA  
Sbjct: 179 VFVYSINDRQSYEELVQVKRQVESVRKST-SLTAVLAANKTDLLHDRQVTQKEGEDLAEE 355

Query: 143 WKCAFMETSA 152
             C   E SA
Sbjct: 356 IGCRLYEVSA 385
>26536
          Length = 829

 Score = 65.9 bits (159), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 41/145 (28%), Positives = 67/145 (46%), Gaps = 15/145 (10%)
 Frame = +2

Query: 37  IPTVEDTYRQVISCDKSICTLQIT---------------DTTGSHQFPAMQRLSISKGHA 81
           +P    T R    C+++I  L +T               DT G  ++ +M+      G  
Sbjct: 29  MPPKPQTRRNK*RCERTIMLLSLTTMKMMMERRVSWTFLDTAGQEEYSSMREHYTRSGDG 208

Query: 82  FILVYSITSRQSLEELKPIYEQICEIKGDVESIPIMLVGNKCDESPNREVQSSEAEALAR 141
           FI+VYS+T   S +E + ++  +   + D  SI  +L GNK D + +R+V   E   +A 
Sbjct: 209 FIVVYSVTDVTSFQEAEAVFRWLTRFQ-DETSIHAVLCGNKTDLTSDRKVTPEEGRKMAD 385

Query: 142 TWKCAFMETSAKLNHNVKELFQELL 166
                + ETSAK   NV +++  LL
Sbjct: 386 RLGMLYFETSAKTGDNVSQVYHGLL 460

 Score = 61.6 bits (148), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 24/48 (50%), Positives = 36/48 (75%)
 Frame = +2

Query: 1   MPEQSNDYRVAVFGAGGVGKSSLVLRFVKGTFRESYIPTVEDTYRQVI 48
           +P    DY++ + G+GGVGKSSL +RF + TF + Y PT+ED+YR++I
Sbjct: 467 IPRSGTDYKIVMLGSGGVGKSSLTIRFTQDTFLDVYDPTIEDSYRKMI 610
>14456
          Length = 1867

 Score = 62.0 bits (149), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 56/173 (32%), Positives = 84/173 (48%), Gaps = 14/173 (8%)
 Frame = -1

Query: 16   GGVGKSSLVLRFVKGTFRESYIPT--VEDTYRQVISCDKSICTLQITDTTGSHQFPAMQR 73
            GGVGKSSL+ RFV   F      T  VE   + V+  D    T+QI DT G  +F +++ 
Sbjct: 1114 GGVGKSSLMNRFVSNKFDAQSFHTIGVEFLNKDVV-VDDETYTMQIWDTAGQERFKSLRT 938

Query: 74   LSISKGHAFILVYSITSRQSLEELKPIYEQI---CEIKGDVESIPIMLVGNKCDESPNRE 130
                     +L +S+ S QS   L    ++     +I+  V + P +++GNK D    R+
Sbjct: 937  PFYRGADCCLLTFSVDSMQSFRNLSMWRKEFLYYADIQDGV-TFPFVVLGNKID-VEGRQ 764

Query: 131  VQSSEAEALARTWKCA-----FMETSAKLNHNVKELF----QELLNLEKRRTV 174
            V + E    AR+W  A     + ETSAK   NV++ F    Q L  +E ++ V
Sbjct: 763  VTNEE----ARSWCTANSNAPYFETSAKDATNVEKAFLAAVQRLREVEDQQEV 617
>19656
          Length = 428

 Score = 58.2 bits (139), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 28/90 (31%), Positives = 44/90 (48%)
 Frame = +3

Query: 9   RVAVFGAGGVGKSSLVLRFVKGTFRESYIPTVEDTYRQVISCDKSICTLQITDTTGSHQF 68
           +  V G G VGK+ L++ +    F   YIPTV D Y   +  D     L + DT G   +
Sbjct: 117 KCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGRPVNLGLWDTAGQEDY 296

Query: 69  PAMQRLSISKGHAFILVYSITSRQSLEELK 98
             ++ LS  +   F+L +S+ S  S E ++
Sbjct: 297 DRLRPLSYPQTDVFLLCFSVASPASFENIR 386
>01398
          Length = 1421

 Score = 54.3 bits (129), Expect = 4e-08,   Method: Compositional matrix adjust.
 Identities = 29/85 (34%), Positives = 45/85 (52%), Gaps = 2/85 (2%)
 Frame = -2

Query: 83   ILVYSITSRQSLEELKPIYEQICEIKGDVE--SIPIMLVGNKCDESPNREVQSSEAEALA 140
            I+VY IT R + E LK  YE   E +  +E      +++G+K D    R+V + E    A
Sbjct: 1366 IIVYDITKRSTFENLKQWYE---EARNHIEPHKAIFLVLGHKSDREDARQVTAREGRRFA 1196

Query: 141  RTWKCAFMETSAKLNHNVKELFQEL 165
                  F ETSAK  HN++++F ++
Sbjct: 1195 EMHGLKFFETSAKSGHNIEDVFAQI 1121
>33794
          Length = 779

 Score = 52.8 bits (125), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 39/117 (33%), Positives = 60/117 (51%), Gaps = 1/117 (0%)
 Frame = -1

Query: 57  LQITDTTGSHQFPAMQRLSISKG-HAFILVYSITSRQSLEELKPIYEQICEIKGDVESIP 115
           LQI DT+G  +F  + R S S+G    ILVY IT++ S +    I   + E++     IP
Sbjct: 644 LQIWDTSGQGRFCTIIR-SYSRGAQGIILVYDITNKWSFDG---IDRWLKEVEEHAPGIP 477

Query: 116 IMLVGNKCDESPNREVQSSEAEALARTWKCAFMETSAKLNHNVKELFQELLNLEKRR 172
            +LVGN+   +  R+V + +AE  A     +  E S   + N++E F EL  +   R
Sbjct: 476 KVLVGNRLHLAYKRQVAAKQAETYASRNNMSCFEISPLCDFNIRESFCELARMALHR 306
>32723
          Length = 384

 Score = 52.0 bits (123), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 32/96 (33%), Positives = 51/96 (53%)
 Frame = +2

Query: 67  QFPAMQRLSISKGHAFILVYSITSRQSLEELKPIYEQICEIKGDVESIPIMLVGNKCDES 126
           +F ++ +      +A ILVY + S+QS E L     +I    G    +   LVGNK D++
Sbjct: 8   RFRSITQSYYRSANALILVYDVCSQQSYESLPQWIHEIELYAGT--KVLAFLVGNKIDQT 181

Query: 127 PNREVQSSEAEALARTWKCAFMETSAKLNHNVKELF 162
             RE+ +   +  A  ++  F+ETSAK   NV++LF
Sbjct: 182 DKREIPTHIGKEFAERYEMRFLETSAKEADNVEKLF 289
>31291
          Length = 446

 Score = 50.4 bits (119), Expect = 5e-07,   Method: Compositional matrix adjust.
 Identities = 38/137 (27%), Positives = 65/137 (47%), Gaps = 13/137 (9%)
 Frame = -1

Query: 57  LQITDTTGSHQFPAMQRLSISKGHAFILVYSITSRQSLEELKPIYEQICEIKGDVESIPI 116
           LQ+ DT G   +  ++ L+      F+L +S+ S  S++ +K  +    EI+     +PI
Sbjct: 446 LQLWDTAGQEDYDRLRPLAYPNTDVFMLXFSLMSEASMKNVKVKW--YPEIRHHDPHVPI 273

Query: 117 MLVGNKCDESPNRE------------VQSSEAEALARTWKCA-FMETSAKLNHNVKELFQ 163
           +LVG K D   ++E            V S++   LA+  K   + E S+K   N+K  F+
Sbjct: 272 VLVGTKLDLRQDKEAVRKLRSSRQDPVSSNQGNDLAKAIKAKRYFECSSKTQENLKTAFE 93

Query: 164 ELLNLEKRRTVSLQIDG 180
           E +       V+L +DG
Sbjct: 92  ETVR------VALNMDG 60
>34597
          Length = 773

 Score = 49.3 bits (116), Expect = 9e-07,   Method: Compositional matrix adjust.
 Identities = 35/92 (38%), Positives = 47/92 (51%)
 Frame = -2

Query: 74  LSISKGHAFILVYSITSRQSLEELKPIYEQICEIKGDVESIPIMLVGNKCDESPNREVQS 133
           LS S GH   L+ +   ++S E +      I E     E +  M++GNKCD +  R V  
Sbjct: 763 LSWSDGHNACLM-T*RMKKSFENIVKWLRNIDEHAN--EDVEKMILGNKCDMTDKRVVSK 593

Query: 134 SEAEALARTWKCAFMETSAKLNHNVKELFQEL 165
              EA+AR     FMETSAK N N++  F EL
Sbjct: 592 ERGEAIAREHSIRFMETSAKSNINIERAFCEL 497
>01972
          Length = 2359

 Score = 45.1 bits (105), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 28/109 (25%), Positives = 56/109 (51%)
 Frame = +3

Query: 57  LQITDTTGSHQFPAMQRLSISKGHAFILVYSITSRQSLEELKPIYEQICEIKGDVESIPI 116
             + DT G  +F  ++     +G   ++++ +TSR + + +   +  +  +    E+IPI
Sbjct: 453 FNVWDTAGQEKFGGLRDGYYIQGQCAVIMFDVTSRVTYKNVPNWHRDLVRV---CENIPI 623

Query: 117 MLVGNKCDESPNREVQSSEAEALARTWKCAFMETSAKLNHNVKELFQEL 165
           +L GNK D   +R+V+ ++A    R     + + SAK N+N ++ F  L
Sbjct: 624 VLCGNKVDIK-DRKVK-AKAIVFHRKKNLQYYDISAKSNYNFEKPFLWL 764
>01095
          Length = 1745

 Score = 43.5 bits (101), Expect = 6e-05,   Method: Compositional matrix adjust.
 Identities = 28/79 (35%), Positives = 42/79 (53%)
 Frame = -1

Query: 84   LVYSITSRQSLEELKPIYEQICEIKGDVESIPIMLVGNKCDESPNREVQSSEAEALARTW 143
            +VY IT++ +    K   +++   +    +I I L GNK D +  R V+  EA+A A   
Sbjct: 1745 VVYDITNQDTFGRAKTWVKELQ--RQASPNIVIALAGNKADLANKRMVEFEEAQAYAEEN 1572

Query: 144  KCAFMETSAKLNHNVKELF 162
               FMETSAK   NV ++F
Sbjct: 1571 SLLFMETSAKTAMNVNDIF 1515
>29380
          Length = 853

 Score = 43.1 bits (100), Expect = 8e-05,   Method: Compositional matrix adjust.
 Identities = 34/105 (32%), Positives = 53/105 (50%), Gaps = 5/105 (4%)
 Frame = -2

Query: 81  AFILVYSI----TSRQSLEELKPIYEQICEIKGDVESIPIMLVGNKCD-ESPNREVQSSE 135
           A I+VY +    T  ++L  +K + +Q      + ES+ I+L GNK D  + +R V   +
Sbjct: 846 AAIIVYDVNIADTFSRALAWVKELRQQ------NTESVLIILAGNKVDLATQHRAVSFED 685

Query: 136 AEALARTWKCAFMETSAKLNHNVKELFQELLNLEKRRTVSLQIDG 180
           A++ AR     F E SAK    V E+F  L N    + +  +IDG
Sbjct: 684 AQSFARENGLLFAEVSAKTGMAVNEIFMTLAN----QLIQQEIDG 562
>33380
          Length = 282

 Score = 42.4 bits (98), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 23/73 (31%), Positives = 35/73 (47%)
 Frame = +3

Query: 57  LQITDTTGSHQFPAMQRLSISKGHAFILVYSITSRQSLEELKPIYEQICEIKGDVESIPI 116
           LQI DT G  ++  +          FIL+Y +T+ +S   ++    QI     D  +  +
Sbjct: 66  LQIWDTAGQERYRTITTAYYRGAMGFILMYDVTNEESFNAVQDWCTQIKTYSWD--NAQV 239

Query: 117 MLVGNKCDESPNR 129
           +LVGNKCD    R
Sbjct: 240 VLVGNKCDLEDER 278
>34359
          Length = 1042

 Score = 39.3 bits (90), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 25/119 (21%), Positives = 60/119 (50%), Gaps = 1/119 (0%)
 Frame = +3

Query: 7   DYRVAVFGAGGVGKSSLVLRFVKGTFRESYIPTVE-DTYRQVISCDKSICTLQITDTTGS 65
           ++++ + G      +++V R V G+ ++ Y+ T+  + +    +  + +    + DT G 
Sbjct: 51  NFKLVLVGGRWEWANNIVKRHVTGS*KK-YVATLGVEVHPLQFNTSRGLLRFNVWDTAGQ 227

Query: 66  HQFPAMQRLSISKGHAFILVYSITSRQSLEELKPIYEQICEIKGDVESIPIMLVGNKCD 124
            +F  ++     +G   I+++ +TSR + + +   +  +  +    E+IPI+L GNK D
Sbjct: 228 EKFGGLRDGYYIQGTCAIIMFDVTSRVTYKNVPNWHRDLVRV---CENIPIVLCGNKVD 395
>09204
          Length = 1051

 Score = 37.0 bits (84), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 28/103 (27%), Positives = 49/103 (47%), Gaps = 4/103 (3%)
 Frame = -3

Query: 67   QFPAMQRLSISKGHAFILVYSITSRQSLEELKPIYEQICEIKGDVESIPIMLVGNKCD-- 124
            ++ AM R+      A IL + +T + S + ++     I E++   E   + + G K D  
Sbjct: 1049 RYEAMSRIYYRGAKAAILCFDLTDKSSFDRIRF---WIGELRQHEEECKLYICGTKFDLV 879

Query: 125  -ESPNRE-VQSSEAEALARTWKCAFMETSAKLNHNVKELFQEL 165
             + P R  V  S A+ALA        ETS+    N+++LF ++
Sbjct: 878  HDDPERRAVPRSVAKALADDCMAEIYETSSMTGDNIEKLFTKI 750
>00552
          Length = 455

 Score = 31.2 bits (69), Expect = 0.32,   Method: Compositional matrix adjust.
 Identities = 16/37 (43%), Positives = 21/37 (56%)
 Frame = -1

Query: 4   QSNDYRVAVFGAGGVGKSSLVLRFVKGTFRESYIPTV 40
           +S   +V + G GGVGKSSL+ RFV   F      T+
Sbjct: 455 KSRLLKVVLLGDGGVGKSSLMNRFVSNKFDAQSFHTI 345
>10708
          Length = 2775

 Score = 31.2 bits (69), Expect = 0.33,   Method: Compositional matrix adjust.
 Identities = 26/86 (30%), Positives = 41/86 (47%), Gaps = 13/86 (15%)
 Frame = -3

Query: 91   RQSLEELKPIYEQICEIKGDVESIPIMLVGNK----CDESPNRE--------VQSSEAEA 138
            R SL++  P     C       ++PI+LVGNK     DE+  RE        V+  E  A
Sbjct: 2602 RTSLKKWTPEVRHFCP------NVPIILVGNKKDLRNDENTKRELMKMKQEPVRLDEGRA 2441

Query: 139  LARTWKC-AFMETSAKLNHNVKELFQ 163
            ++      +++E SAK    V+E+F+
Sbjct: 2440 MSEKINAYSYLECSAKTKEGVREVFE 2363
>00780
          Length = 1650

 Score = 30.8 bits (68), Expect = 0.38,   Method: Compositional matrix adjust.
 Identities = 22/69 (31%), Positives = 30/69 (43%), Gaps = 4/69 (5%)
 Frame = +3

Query: 23   LVLRFVKGTFRESYIPTVEDTYRQVISCDKSI-CTLQITDTTGSHQFPAMQRLSI---SK 78
            L  R + GT R + IPT  D Y   +  D  I   + +++    H  P   R S    S+
Sbjct: 1140 LARRLIIGTLRXNAIPTKFDXYINFVISDSMINVQMTLSNNDFKHNLPICVRFSSEIRSE 1319

Query: 79   GHAFILVYS 87
              A IL YS
Sbjct: 1320 SKAAILFYS 1346
>11378
          Length = 1688

 Score = 28.1 bits (61), Expect = 2.7,   Method: Compositional matrix adjust.
 Identities = 26/126 (20%), Positives = 51/126 (40%), Gaps = 9/126 (7%)
 Frame = +3

Query: 9   RVAVFGAGGVGKSSLVLRFVKGTFRESYIPTVEDTYRQVISCDKSICTLQITDTTGSHQ- 67
           ++   G    GK++L L  +K      ++PT+  T  ++        T  +    G H+ 
Sbjct: 327 KLVFLGLDNAGKTTL-LHMLKDDKMAQHVPTLHPTSEELSMGGMRFTTFDL----GGHRQ 491

Query: 68  --------FPAMQRLSISKGHAFILVYSITSRQSLEELKPIYEQICEIKGDVESIPIMLV 119
                   FPA+           + +  +  R+ L E K   + +   +  V + PI+++
Sbjct: 492 ARRVWKDYFPAVD--------GIVFLVDVHDRERLVEAKAELDSLMTDE-QVANAPILVL 644

Query: 120 GNKCDE 125
           GNK D+
Sbjct: 645 GNKIDK 662
>18949
          Length = 414

 Score = 27.3 bits (59), Expect = 4.1,   Method: Compositional matrix adjust.
 Identities = 16/61 (26%), Positives = 30/61 (49%), Gaps = 9/61 (14%)
 Frame = +3

Query: 102 EQICEIKGDVES---------IPIMLVGNKCDESPNREVQSSEAEALARTWKCAFMETSA 152
           E+I E K +++S         IP++++GNK D+    E ++S+       W C  ++   
Sbjct: 168 ERITEAKAELDSLLRDDQIADIPVLVLGNKMDKHGVVERRTSDT-----GWACTALQART 332

Query: 153 K 153
           K
Sbjct: 333 K 335
>27191
          Length = 443

 Score = 26.6 bits (57), Expect = 7.3,   Method: Compositional matrix adjust.
 Identities = 10/24 (41%), Positives = 15/24 (62%)
 Frame = +2

Query: 144 KCAFMETSAKLNHNVKELFQELLN 167
           KC + ETSA     V ++FQ++L 
Sbjct: 368 KCLYYETSAATGEGVDDMFQQMLQ 439
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|11496255|ref|NP_067397.1| heat shock protein,
DNAJ-like 4 [Mus musculus]
         (397 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

14550                                                                 102   2e-37
12040                                                                 147   8e-36
10680                                                                  95   5e-20
20488                                                                  95   6e-20
02324                                                                  81   7e-16
13998                                                                  64   2e-10
26984                                                                  62   4e-10
02088                                                                  58   7e-09
22505                                                                  41   3e-07
13422                                                                  45   6e-05
07620                                                                  42   4e-04
18150                                                                  30   0.001
15360                                                                  40   0.002
20155                                                                  33   0.25 
38321                                                                  32   0.47 
17270                                                                  32   0.53 
12753                                                                  31   0.85 
17683                                                                  30   2.4  
33510                                                                  29   3.5  
08366                                                                  29   4.0  
>14550
          Length = 1395

 Score =  102 bits (253), Expect(2) = 2e-37,   Method: Compositional matrix adjust.
 Identities = 81/242 (33%), Positives = 118/242 (48%), Gaps = 1/242 (0%)
 Frame = -2

Query: 107 NVVHQLSVTLEDLYNGITKKLALQKNVXXXXXXXXXXXXXSVEKCPLCKGRGMQVHIQQI 166
           +VV  L VTLE+LY+G   ++   K V                KC  C+   M+   QQ+
Sbjct: 809 DVVMDLDVTLEELYSGDFVEVLRYKPVSKPAKGK--------RKCN-CR---METVTQQL 666

Query: 167 GPGMVQQIQTVCIECKGQGERINPKDRCENCSGAKVTREKKIIEVHVEKGMKDGQKILFH 226
           GPG  Q  Q               +  C+ C   K   E+K++EV +E GM+DGQ+  F 
Sbjct: 665 GPGRFQMSQ---------------QQVCDECPNIKFVPEEKVLEVEIEPGMRDGQEYPFV 531

Query: 227 GEGDQEPELDPGDVIIVLDQKDHSVFQRRGQDLIMKMKIQLSEALCGFKKTIKTLDD-RV 285
            EG+   + +PGD+  ++ Q  H+ F+R+G DL   + + L +AL GF+  I  LD  +V
Sbjct: 530 AEGEPHMDGEPGDLRFIIRQVKHARFERKGDDLYTNVTVSLQDALIGFEMDIVHLDGHKV 351

Query: 286 LVISSKSGEVIKHGDLKCIRNEGMPIYKAPLEKGVMIIQFLVVFPEKQWLSQEKLPQLEA 345
            VI  K   +   G      NEGMP Y+    KG + I F + FP K  LS+E    L+A
Sbjct: 350 HVIRDK---ITWPGARMRKSNEGMPNYENNNVKGSLFITFDIDFP-KGTLSEEDKEGLKA 183

Query: 346 LL 347
           +L
Sbjct: 182 IL 177

 Score = 72.0 bits (175), Expect(2) = 2e-37,   Method: Compositional matrix adjust.
 Identities = 36/71 (50%), Positives = 52/71 (73%), Gaps = 3/71 (4%)
 Frame = -1

Query: 7    YYDILGVKPSASPEEIKKAYRKLALKYHPDKNPDEGE---KFKLISQAYEVLSDPKKRDI 63
            +Y ILGV  SA  ++IK+AYRK+A + HPDKN D+ E   +F+ +  AYEVLSD +KR +
Sbjct: 1131 FYKILGVSKSADTKQIKRAYRKIAKELHPDKNRDDPEAEQRFQDLGAAYEVLSDEEKRKV 952

Query: 64   YDQGGEQAIKE 74
            YD+ GE+ +K+
Sbjct: 951  YDRHGEEGLKQ 919

 Score = 32.0 bits (71), Expect = 0.47,   Method: Compositional matrix adjust.
 Identities = 19/42 (45%), Positives = 25/42 (59%)
 Frame = -1

Query: 306  NEGMPIYKAPLEKGVMIIQFLVVFPEKQWLSQEKLPQLEALL 347
            NEGMP Y+    KG + I F + FP K  LS+E    L+A+L
Sbjct: 1383 NEGMPNYENNNVKGSLFITFDIDFP-KGTLSEEDKEGLKAIL 1261
>12040
          Length = 1151

 Score =  147 bits (371), Expect = 8e-36,   Method: Compositional matrix adjust.
 Identities = 69/147 (46%), Positives = 104/147 (70%)
 Frame = -2

Query: 239  DVIIVLDQKDHSVFQRRGQDLIMKMKIQLSEALCGFKKTIKTLDDRVLVISSKSGEVIKH 298
            D+II+LD+K+HS F   G DL+MKM +QL EALCGF++ +KT+DDR L+++++ GEVI+H
Sbjct: 1150 DIIILLDEKEHSTFVHAGTDLMMKMPLQLVEALCGFQRIVKTMDDRDLLVATQPGEVIRH 971

Query: 299  GDLKCIRNEGMPIYKAPLEKGVMIIQFLVVFPEKQWLSQEKLPQLEALLPPRQKVRITDD 358
               KCI  EGMPI+K P+EKG +IIQF V+FP+   ++   +P L+  LPP  ++ I  +
Sbjct: 970  EMTKCIAEEGMPIFKNPMEKGTLIIQFEVIFPD--VINPSVIPTLKQCLPPAPEIDIPIE 797

Query: 359  MDQVELKEFNPNEQSWRQHREAYEEDD 385
             +   L++F+P ++     R AY+EDD
Sbjct: 796  AEHTVLEDFDPKQRRQPNQRMAYDEDD 716
>10680
          Length = 1093

 Score = 95.1 bits (235), Expect = 5e-20,   Method: Compositional matrix adjust.
 Identities = 54/138 (39%), Positives = 74/138 (53%)
 Frame = -3

Query: 193 RCENCSGAKVTREKKIIEVHVEKGMKDGQKILFHGEGDQEPELDPGDVIIVLDQKDHSVF 252
           R  N  G   +   KI+ + V+KG K G KI F  EGDQ P   P D++ ++  K H  F
Sbjct: 770 RVMNEDGHTSSIRDKILTITVKKGWKPGTKITFPKEGDQGPNNVPADIVFIVKDKPHPRF 591

Query: 253 QRRGQDLIMKMKIQLSEALCGFKKTIKTLDDRVLVISSKSGEVIKHGDLKCIRNEGMPIY 312
           +R G +LI    + L  AL G    I TLDDR L I     +++K G  K +  EGMP+ 
Sbjct: 590 RREGLNLIHTANVLLGRALTGTTVDIHTLDDRTLHIPIN--DIVKPGYKKIVPGEGMPMS 417

Query: 313 KAPLEKGVMIIQFLVVFP 330
             P +KG +II+F + FP
Sbjct: 416 SDPTQKGDLIIEFNIEFP 363
>20488
          Length = 3281

 Score = 94.7 bits (234), Expect = 6e-20,   Method: Compositional matrix adjust.
 Identities = 54/138 (39%), Positives = 73/138 (52%)
 Frame = -2

Query: 193  RCENCSGAKVTREKKIIEVHVEKGMKDGQKILFHGEGDQEPELDPGDVIIVLDQKDHSVF 252
            R  N  G   +   KI+ + V+KG K G KI F  EGDQ P   P D++ ++  K H  F
Sbjct: 1627 RVMNEDGHTSSIRDKILTITVKKGWKPGTKITFPKEGDQGPNNVPADIVFIVKDKPHPRF 1448

Query: 253  QRRGQDLIMKMKIQLSEALCGFKKTIKTLDDRVLVISSKSGEVIKHGDLKCIRNEGMPIY 312
            +R G +LI    + L  AL G    I TLDDR L I     +++K G  K +  EGMP+ 
Sbjct: 1447 RREGLNLIHTANVLLGRALTGTTVDIHTLDDRTLHIPIN--DIVKPGYKKIVPGEGMPMS 1274

Query: 313  KAPLEKGVMIIQFLVVFP 330
              P ZKG +II+F + FP
Sbjct: 1273 SDPTZKGDLIIEFNIEFP 1220
>02324
          Length = 2058

 Score = 81.3 bits (199), Expect = 7e-16,   Method: Compositional matrix adjust.
 Identities = 37/71 (52%), Positives = 55/71 (77%), Gaps = 4/71 (5%)
 Frame = +2

Query: 7   YYDILGVKPSASPEEIKKAYRKLALKYHPDKNPDEGE----KFKLISQAYEVLSDPKKRD 62
           +Y++LGV+ SA  +++KKAYRKLALK+HPDKNPD  E    +F+L+ QAYE+L+DP++R 
Sbjct: 107 HYEVLGVERSADNDDLKKAYRKLALKFHPDKNPDSVEEATAQFRLVQQAYEILTDPQERS 286

Query: 63  IYDQGGEQAIK 73
            YD+  E  ++
Sbjct: 287 WYDRHREAILR 319
>13998
          Length = 1075

 Score = 63.5 bits (153), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 34/73 (46%), Positives = 45/73 (61%), Gaps = 8/73 (10%)
 Frame = +1

Query: 3   KETQYYDILGVKPSASPEEIKKAYRKLALKYHPDKNP--------DEGEKFKLISQAYEV 54
           K   YY ILG+  +A+ +EIKKAYRK AL +HPD++         DE  KFK + +AY +
Sbjct: 196 KRKDYYKILGISRNATEDEIKKAYRKKALVHHPDRHANSSADVRKDEELKFKEVGEAYAI 375

Query: 55  LSDPKKRDIYDQG 67
           LSD  K+  YD G
Sbjct: 376 LSDGAKKTRYDSG 414
>26984
          Length = 1107

 Score = 62.0 bits (149), Expect = 4e-10,   Method: Compositional matrix adjust.
 Identities = 29/60 (48%), Positives = 41/60 (68%), Gaps = 2/60 (3%)
 Frame = -2

Query: 8   YDILGVKPSASPEEIKKAYRKLALKYHPDKNPDEG--EKFKLISQAYEVLSDPKKRDIYD 65
           Y ILG++  AS E+IK+ YR+ A+  HPDKN + G  E FK++  A+E++ DP KR  YD
Sbjct: 509 YSILGLRADASDEDIKRYYRRQAVLVHPDKNQEPGAEEAFKILGHAFEMIGDPTKRKEYD 330
>02088
          Length = 1062

 Score = 57.8 bits (138), Expect = 7e-09,   Method: Compositional matrix adjust.
 Identities = 29/74 (39%), Positives = 47/74 (63%), Gaps = 5/74 (6%)
 Frame = +3

Query: 1   MVKETQYYDILGVKPSASPEEIKKAYRKLALKYHPDK-NPDEGE----KFKLISQAYEVL 55
           + + T  Y+++G++  A+P+E+KK Y K++L  HPD+ +  E E    KF+ + + Y VL
Sbjct: 93  LFETTDLYEVIGIRREATPQEVKKGYHKVSLAVHPDQVSAAEKETATRKFQTLGKVYTVL 272

Query: 56  SDPKKRDIYDQGGE 69
           SD  KR  YD+ GE
Sbjct: 273 SDKDKRAXYDETGE 314
>22505
          Length = 784

 Score = 40.8 bits (94), Expect(2) = 3e-07,   Method: Compositional matrix adjust.
 Identities = 20/31 (64%), Positives = 23/31 (74%)
 Frame = -1

Query: 8   YDILGVKPSASPEEIKKAYRKLALKYHPDKN 38
           Y ILGV P A+ ++I KAYRK ALK HPDK 
Sbjct: 646 YGILGVGPEANEKQIVKAYRKKALKCHPDKT 554

 Score = 31.2 bits (69), Expect(2) = 3e-07,   Method: Compositional matrix adjust.
 Identities = 15/33 (45%), Positives = 20/33 (60%)
 Frame = -3

Query: 34  HPDKNPDEGEKFKLISQAYEVLSDPKKRDIYDQ 66
           +PD NP   E F  +S+A EVL+DP  +  YD 
Sbjct: 557 NPD-NPKAAELFHELSKALEVLTDPSAKAAYDN 462
>13422
          Length = 930

 Score = 45.1 bits (105), Expect = 6e-05,   Method: Compositional matrix adjust.
 Identities = 27/74 (36%), Positives = 41/74 (55%), Gaps = 11/74 (14%)
 Frame = +1

Query: 3   KETQYYDILGV---KPSASPEEIKKAYRKLALKYHPDKNPDEG--------EKFKLISQA 51
           K+  +Y +LG+   +  A+ + IK+ YR+  L +HPDK    G        + F  IS+A
Sbjct: 328 KKQDHYAVLGLSKLRYKATADHIKRIYRQKVLLHHPDKRRARGLHVENGENDYFLCISRA 507

Query: 52  YEVLSDPKKRDIYD 65
           YE+L DP KR  +D
Sbjct: 508 YEILGDPVKRRSFD 549
>07620
          Length = 1775

 Score = 42.4 bits (98), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 18/32 (56%), Positives = 24/32 (75%)
 Frame = +1

Query: 7   YYDILGVKPSASPEEIKKAYRKLALKYHPDKN 38
           YY++L VK   +  ++KKAYRKLAL+ HPDK 
Sbjct: 103 YYEVLDVKKDCTESDMKKAYRKLALQMHPDKT 198
>18150
          Length = 768

 Score = 30.0 bits (66), Expect(2) = 0.001,   Method: Compositional matrix adjust.
 Identities = 12/28 (42%), Positives = 20/28 (71%)
 Frame = +3

Query: 17 ASPEEIKKAYRKLALKYHPDKNPDEGEK 44
          A+ EE+  A+R+L+  YHPDK+ +  +K
Sbjct: 3  ATTEEVNNAFRRLSKIYHPDKHLEAAKK 86

 Score = 29.6 bits (65), Expect(2) = 0.001,   Method: Compositional matrix adjust.
 Identities = 12/24 (50%), Positives = 18/24 (75%)
 Frame = +2

Query: 50  QAYEVLSDPKKRDIYDQGGEQAIK 73
           +A+E+LSD  KR IYD  GE+ ++
Sbjct: 119 EAHEILSDKHKRTIYDTYGEKGLE 190
>15360
          Length = 502

 Score = 39.7 bits (91), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 17/52 (32%), Positives = 34/52 (65%), Gaps = 3/52 (5%)
 Frame = +1

Query: 8   YDILGVKPSASPEEIKKAYRKLALKYHPDKNPDEGE---KFKLISQAYEVLS 56
           +++L +   +  E +K  Y++LALK+HP+K+ +  E   +F  ++QAY +L+
Sbjct: 61  FNLLDIPAGSDQESLKTKYKQLALKWHPEKHKNAAEAVKQFIQVTQAYRLLA 216
>20155
          Length = 484

 Score = 32.7 bits (73), Expect = 0.25,   Method: Compositional matrix adjust.
 Identities = 15/29 (51%), Positives = 21/29 (72%)
 Frame = +1

Query: 10  ILGVKPSASPEEIKKAYRKLALKYHPDKN 38
           ILGV PSAS  +IK A++++ L  HPD+ 
Sbjct: 151 ILGVSPSASKVKIKDAHKRIMLLNHPDRG 237
>38321
          Length = 1059

 Score = 32.0 bits (71), Expect = 0.47,   Method: Compositional matrix adjust.
 Identities = 19/42 (45%), Positives = 25/42 (59%)
 Frame = -1

Query: 306  NEGMPIYKAPLEKGVMIIQFLVVFPEKQWLSQEKLPQLEALL 347
            NEGMP Y+    KG + I F + FP K  LS+E    L+A+L
Sbjct: 1047 NEGMPNYENNNVKGSLFITFDIDFP-KGTLSEEDKEGLKAIL 925
>17270
          Length = 1144

 Score = 31.6 bits (70), Expect = 0.53,   Method: Compositional matrix adjust.
 Identities = 18/39 (46%), Positives = 25/39 (64%), Gaps = 4/39 (10%)
 Frame = +3

Query: 16  SASPE--EIKKAYRKLALKYHPDK--NPDEGEKFKLISQ 50
           SA+PE  EIKK Y+K  + YHPDK      G  +K++S+
Sbjct: 312 SANPEWTEIKKLYQKAVIHYHPDKVDVATHGNTWKVLSE 428
>12753
          Length = 893

 Score = 31.2 bits (69), Expect = 0.85,   Method: Compositional matrix adjust.
 Identities = 13/46 (28%), Positives = 26/46 (56%)
 Frame = -2

Query: 309 MPIYKAPLEKGVMIIQFLVVFPEKQWLSQEKLPQLEALLPPRQKVR 354
           + IYK+   + + + ++++   +K+WL Q KL  L  LL  ++  R
Sbjct: 802 VQIYKSGCTEQIYLYRYVITNNKKKWLQQRKLMHLATLLTKQKSNR 665
>17683
          Length = 450

 Score = 29.6 bits (65), Expect = 2.4,   Method: Compositional matrix adjust.
 Identities = 14/24 (58%), Positives = 18/24 (75%), Gaps = 2/24 (8%)
 Frame = +2

Query: 16  SASPE--EIKKAYRKLALKYHPDK 37
           SA+PE  E+KK Y+K  + YHPDK
Sbjct: 371 SANPEWSEVKKLYQKAVIHYHPDK 442
>33510
          Length = 501

 Score = 28.9 bits (63), Expect = 3.5,   Method: Compositional matrix adjust.
 Identities = 17/59 (28%), Positives = 28/59 (47%), Gaps = 6/59 (10%)
 Frame = +3

Query: 12  GVKPSASPEEIKKAYRKLALKYHPDKNPDEGEK------FKLISQAYEVLSDPKKRDIY 64
           G+    S +++KK YRK  L  HPDK  D+  +      F  ++ A+    D   + +Y
Sbjct: 276 GMHDLVSADQVKKVYRKAVLSVHPDKLHDDPHEALAKLIFMELNDAWAKFEDEGMKSLY 452
>08366
          Length = 2167

 Score = 28.9 bits (63), Expect = 4.0,   Method: Compositional matrix adjust.
 Identities = 17/39 (43%), Positives = 26/39 (66%), Gaps = 4/39 (10%)
 Frame = +1

Query: 16  SASPE--EIKKAYRKLALKYHPDKNPDE--GEKFKLISQ 50
           S  PE  E+KK Y+K  + YHPDK  +E  G K+K++++
Sbjct: 703 SEQPEIAEMKKLYQKAIVHYHPDKVNEEEHGMKWKVLTE 819
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|51317392|ref|NP_082903.2| pleckstrin and Sec7 domain
containing homolog [Mus musculus]
         (1024 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

25051                                                                 120   2e-37
11159                                                                 126   4e-29
30249                                                                  59   1e-08
19246                                                                  47   3e-05
29517                                                                  43   8e-04
13952                                                                  32   0.96 
>25051
          Length = 1017

 Score =  120 bits (300), Expect(2) = 2e-37,   Method: Compositional matrix adjust.
 Identities = 60/122 (49%), Positives = 80/122 (65%), Gaps = 1/122 (0%)
 Frame = -2

Query: 745 PFLDLTPEPGAAV-YKHGALVRKVHADPDCRKTPRGKRGWKSFHGILKGMILYLQKEEYQ 803
           PFLD+ P+P   V YK G ++RK   +P  RKTP GKRGW+  + IL+ +ILY  K+E+Q
Sbjct: 950 PFLDV-PDPSKTVEYKKGYVMRKSCMEPGRRKTPFGKRGWRMVYTILRDLILYQYKDEHQ 774

Query: 804 PGKALSEAELKNAISIHHALATRASDYSKRPHVFYLRTADWRVFLFQAPSLEQMQSWITR 863
             K       +N + IHHALAT+ASDY+K+ HVF L+TADW  +LFQ     ++Q WI  
Sbjct: 773 VKKGQFVESSQNVVRIHHALATKASDYTKKQHVFRLQTADWAEYLFQTGGTIELQEWIDT 594

Query: 864 IN 865
           IN
Sbjct: 593 IN 588

 Score = 55.1 bits (131), Expect(2) = 2e-37,   Method: Compositional matrix adjust.
 Identities = 28/65 (43%), Positives = 39/65 (60%)
 Frame = -3

Query: 883 QKKFSRPLLPSAATRLSQEEQVRTHEAKLKAMASELREHRAAHLGKKARGKEADEQRQKE 942
           Q +F RPL+PS+ T+LS  EQ+R HE  +  +  EL+ HRAA   K ++        +KE
Sbjct: 535 QARFQRPLMPSSCTKLSIHEQLRGHEHHISELEQELQLHRAAAPEKGSKSTTISNYIEKE 356

Query: 943 AYLEF 947
            YLEF
Sbjct: 355 NYLEF 341
>11159
          Length = 520

 Score =  126 bits (317), Expect = 4e-29,   Method: Compositional matrix adjust.
 Identities = 65/150 (43%), Positives = 90/150 (60%)
 Frame = +2

Query: 775 KTPRGKRGWKSFHGILKGMILYLQKEEYQPGKALSEAELKNAISIHHALATRASDYSKRP 834
           +TP GKR WK F   L+ ++LYL K+E+   K+     L NAI IHHALAT A+DY+K+ 
Sbjct: 47  ETPFGKRSWKMFFITLRDLVLYLHKDEHGFRKSQMSDNLHNAIRIHHALATMANDYTKKQ 226

Query: 835 HVFYLRTADWRVFLFQAPSLEQMQSWITRINXXXXXXXXXXXXXXXXXQKKFSRPLLPSA 894
           HVF L+TAD   +LFQ    +++ SW+  IN                 QK+F RPLLPSA
Sbjct: 227 HVFRLQTADQAEYLFQTSDSKELHSWVETINYVCAAFSAPPLEAGVGSQKRFQRPLLPSA 406

Query: 895 ATRLSQEEQVRTHEAKLKAMASELREHRAA 924
            T+L  +EQ+ +HE ++  +  EL EH+ A
Sbjct: 407 QTKLLMKEQLESHELQVAQLKHELIEHQKA 496
>30249
          Length = 822

 Score = 58.5 bits (140), Expect = 1e-08,   Method: Composition-based stats.
 Identities = 30/80 (37%), Positives = 49/80 (61%), Gaps = 5/80 (6%)
 Frame = -2

Query: 621 ETQERERVLAHFSQRYFQCNPEAL---SSEDGAHTLTCALMLLNTDLHGHNIG--KRMTC 675
           E Q+ ER++  F++RY QCNP+ +    + D    L  A+++LNTDLH  ++   ++M  
Sbjct: 821 EAQKIERLMEAFAERYCQCNPDQVKNFKTFDTVFLLAFAIIMLNTDLHNSSVKPERKMKL 642

Query: 676 GDFIGNLEGLNDGGDFPREL 695
            DF+ NL G++DG D   +L
Sbjct: 641 EDFVRNLRGIDDGEDVDGDL 582
>19246
          Length = 440

 Score = 47.4 bits (111), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 32/85 (37%), Positives = 40/85 (47%), Gaps = 1/85 (1%)
 Frame = +2

Query: 781 RGWKSFHGILKGMILYLQKEEYQPGKALSEAELKNAISIHHALATRASDYS-KRPHVFYL 839
           R WK    +L+G  L+L K+        + +  +  ISI   L   A DYS KR HVF L
Sbjct: 62  RSWKQVWAVLRGHALFLIKDRRDGSTHPTFSFEEPPISIKSCLVDIAHDYSRKRKHVFRL 241

Query: 840 RTADWRVFLFQAPSLEQMQSWITRI 864
            T    V+L QA     M SWI  I
Sbjct: 242 TTYSESVYLLQAEDKGTMMSWIQAI 316
>29517
          Length = 622

 Score = 42.7 bits (99), Expect = 8e-04,   Method: Compositional matrix adjust.
 Identities = 19/39 (48%), Positives = 26/39 (66%)
 Frame = -1

Query: 827 ASDYSKRPHVFYLRTADWRVFLFQAPSLEQMQSWITRIN 865
           A+DYSKRP+VF L+ +    +LFQA    +  +WI RIN
Sbjct: 589 AADYSKRPYVFRLKLSSGSEYLFQAKDAAERDTWIGRIN 473
>13952
          Length = 577

 Score = 32.3 bits (72), Expect = 0.96,   Method: Composition-based stats.
 Identities = 16/36 (44%), Positives = 19/36 (52%)
 Frame = -3

Query: 674 TCGDFIGNLEGLNDGGDFPRELLKALYSSIKNEKLQ 709
           T   FI     +NDG   P ELL +LY SIK E  +
Sbjct: 575 TVERFIQMNRDINDGDSLPEELLTSLYDSIKKEPFK 468
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6677819|ref|NP_033127.1| Harvey rat sarcoma oncogene,
subgroup R [Mus musculus]
         (218 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

07580                                                                 148   2e-37
00858                                                                 149   8e-37
24619                                                                 112   1e-25
19046                                                                 112   1e-25
26536                                                                  95   3e-20
11257                                                                  86   1e-17
36482                                                                  84   6e-17
08428                                                                  82   1e-16
14456                                                                  82   2e-16
33794                                                                  72   3e-13
18509                                                                  65   3e-13
07465                                                                  70   6e-13
01972                                                                  70   9e-13
33374                                                                  69   2e-12
30760                                                                  68   2e-12
06994                                                                  60   3e-12
33380                                                                  65   3e-11
11728                                                                  62   2e-10
34359                                                                  59   1e-09
34468                                                                  59   1e-09
05468                                                                  59   1e-09
19006                                                                  57   6e-09
12339                                                                  56   1e-08
19656                                                                  55   3e-08
13750                                                                  54   4e-08
01398                                                                  54   4e-08
17511                                                                  54   7e-08
13745                                                                  53   1e-07
31291                                                                  52   1e-07
26083                                                                  50   8e-07
10708                                                                  40   4e-06
01095                                                                  47   4e-06
31928                                                                  47   7e-06
32723                                                                  47   9e-06
25618                                                                  43   1e-04
34597                                                                  43   1e-04
08153                                                                  39   0.002
14119                                                                  37   0.005
35581                                                                  35   0.019
00552                                                                  35   0.031
09700                                                                  33   0.066
18949                                                                  32   0.24 
09827                                                                  32   0.28 
32770                                                                  31   0.35 
11378                                                                  28   2.2  
15662                                                                  28   3.4  
25655                                                                  27   7.5  
>07580
          Length = 921

 Score =  148 bits (374), Expect(2) = 2e-37,   Method: Compositional matrix adjust.
 Identities = 76/165 (46%), Positives = 102/165 (61%)
 Frame = +3

Query: 54  FVSDYDPTIEDSYTKICTVDGIPARLDILDTAGQEEFGAMREQYMRAGNGFLLVFAINDR 113
           FV  YDPTIEDSY K   VDG    L+ILDTAG E+F AMR+ YM+ G GFLL ++I  +
Sbjct: 135 FVEKYDPTIEDSYRKQVEVDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFLLAYSITAQ 314

Query: 114 QSFNEVGKLFTQILRVKDRDDFPIVLVGNKADLENQRQVLRSEASSFSASHHMTYFEASA 173
            +FN++ +L  QILRVKD DD P++LVGNK DLE++R V + +    + S    + E SA
Sbjct: 315 STFNDLQELREQILRVKDTDDVPMLLVGNKCDLEDERVVGKDQGQGLARSFSCAFLETSA 494

Query: 174 KLRLNVDEAFEQLVRAVRKYQEQELPPSPPSAPRKKDGGCPCVLL 218
           K R+NV+E F  LVR + K        SP  + ++      C +L
Sbjct: 495 KARINVNEIFMDLVRQINK-------KSPEQSGKRTKSKKSCTVL 608

 Score = 24.6 bits (52), Expect(2) = 2e-37,   Method: Compositional matrix adjust.
 Identities = 11/25 (44%), Positives = 14/25 (56%)
 Frame = +2

Query: 30 HKLXXXXXXXXXKSALTIQFIQSYF 54
          +KL         KSALT+QF+Q  F
Sbjct: 62 YKLVVLGSGGVGKSALTVQFVQGDF 136
>00858
          Length = 1658

 Score =  149 bits (376), Expect = 8e-37,   Method: Compositional matrix adjust.
 Identities = 80/161 (49%), Positives = 101/161 (62%)
 Frame = -2

Query: 30   HKLXXXXXXXXXKSALTIQFIQSYFVSDYDPTIEDSYTKICTVDGIPARLDILDTAGQEE 89
            +KL         KSALTIQ  Q++FV +YDPT EDS  K   +DG    LDILDTAGQEE
Sbjct: 1588 YKLVVVGAGGVGKSALTIQLXQNHFVEEYDPTXEDSXRKQVVIDGETCLLDILDTAGQEE 1409

Query: 90   FGAMREQYMRAGNGFLLVFAINDRQSFNEVGKLFTQILRVKDRDDFPIVLVGNKADLENQ 149
              AMR+Q MR G GFL VFA+ + +SF ++ +   QI RVKD D+ P+VLVGNK DL   
Sbjct: 1408 XSAMRDQCMRTGEGFLCVFAVXNLKSFEDINQYREQIKRVKDADEVPMVLVGNKVDLPI- 1232

Query: 150  RQVLRSEASSFSASHHMTYFEASAKLRLNVDEAFEQLVRAV 190
            R V + +    +  +H+ Y E SAK R  VD+AF  LVR +
Sbjct: 1231 RNVEQRQGKHMAELYHIPYVETSAKTRQGVDDAFYTLVREI 1109
>24619
          Length = 509

 Score =  112 bits (280), Expect = 1e-25,   Method: Compositional matrix adjust.
 Identities = 57/106 (53%), Positives = 71/106 (66%), Gaps = 1/106 (0%)
 Frame = -2

Query: 87  QEEFGAMREQYMRAGNGFLLVFAINDRQSFNEVGKLFTQILRVKDRDDFPIVLVGNKADL 146
           QEEF AMREQYMR G+GFLLVF++ D QSF  +    TQILRVKDRD +P++L  NK DL
Sbjct: 508 QEEFSAMREQYMRKGDGFLLVFSVIDYQSFENMVNFHTQILRVKDRDTYPMILCANKVDL 329

Query: 147 ENQRQVLRSEASSFSASHHMTYFEASAK-LRLNVDEAFEQLVRAVR 191
            +QR+V   +    +    + Y E SAK   LNVD AF Q+VR +R
Sbjct: 328 VHQRKVSEEQVRDLATRLRIPYIETSAKDPPLNVDLAFHQVVRVIR 191
>19046
          Length = 445

 Score =  112 bits (280), Expect = 1e-25,   Method: Compositional matrix adjust.
 Identities = 56/106 (52%), Positives = 71/106 (66%), Gaps = 1/106 (0%)
 Frame = -2

Query: 87  QEEFGAMREQYMRAGNGFLLVFAINDRQSFNEVGKLFTQILRVKDRDDFPIVLVGNKADL 146
           QEEF AMREQYMR G+GFLLVF++ D +SF  +    TQILRVKDRD +P++L  NK DL
Sbjct: 444 QEEFSAMREQYMRKGDGFLLVFSVTDFRSFENMANFHTQILRVKDRDSYPMILCANKVDL 265

Query: 147 ENQRQVLRSEASSFSASHHMTYFEASAK-LRLNVDEAFEQLVRAVR 191
            +QR+V   +    +    + Y E SAK   LNVD AF Q+VR +R
Sbjct: 264 VHQRKVSEEQVRDLATRLRIPYIETSAKDPPLNVDLAFHQVVRVIR 127
>26536
          Length = 829

 Score = 94.7 bits (234), Expect = 3e-20,   Method: Compositional matrix adjust.
 Identities = 45/109 (41%), Positives = 65/109 (59%)
 Frame = +2

Query: 82  LDTAGQEEFGAMREQYMRAGNGFLLVFAINDRQSFNEVGKLFTQILRVKDRDDFPIVLVG 141
           LDTAGQEE+ +MRE Y R+G+GF++V+++ D  SF E   +F  + R +D      VL G
Sbjct: 143 LDTAGQEEYSSMREHYTRSGDGFIVVYSVTDVTSFQEAEAVFRWLTRFQDETSIHAVLCG 322

Query: 142 NKADLENQRQVLRSEASSFSASHHMTYFEASAKLRLNVDEAFEQLVRAV 190
           NK DL + R+V   E    +    M YFE SAK   NV + +  L+R++
Sbjct: 323 NKTDLTSDRKVTPEEGRKMADRLGMLYFETSAKTGDNVSQVYHGLLRSI 469

 Score = 45.1 bits (105), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 21/35 (60%), Positives = 25/35 (71%)
 Frame = +2

Query: 42  KSALTIQFIQSYFVSDYDPTIEDSYTKICTVDGIP 76
           KS+LTI+F Q  F+  YDPTIEDSY K+  V G P
Sbjct: 524 KSSLTIRFTQDTFLDVYDPTIEDSYRKMIQVSGQP 628
>11257
          Length = 1102

 Score = 86.3 bits (212), Expect = 1e-17,   Method: Compositional matrix adjust.
 Identities = 48/133 (36%), Positives = 78/133 (58%), Gaps = 4/133 (3%)
 Frame = -2

Query: 68   KICTVDGIPARLDILDTAGQEEFGAMREQYMRAGNGFLLVFAINDRQSFNEVGKLFTQIL 127
            K   VDG    + I DTAGQE + ++R  + R  +  LL F++++ +S   +   + + +
Sbjct: 1053 KDVVVDGETFTMQIWDTAGQERYKSLRTPFYRGTDCCLLTFSVDNLKSLQSLSDWYDEFV 874

Query: 128  RVKDRDD---FPIVLVGNKADLENQRQVLRSEASSFSASH-HMTYFEASAKLRLNVDEAF 183
               D  D   FP V++GNKAD+E +R+V   +A ++  +H ++ YFE SAK  LNV +AF
Sbjct: 873  NYADIQDSASFPFVIIGNKADIE-EREVSSEDAYNWCRTHGNLPYFETSAKDSLNVQQAF 697

Query: 184  EQLVRAVRKYQEQ 196
              +VR +R+  EQ
Sbjct: 696  LAVVRRLREMDEQ 658
>36482
          Length = 686

 Score = 83.6 bits (205), Expect = 6e-17,   Method: Compositional matrix adjust.
 Identities = 50/155 (32%), Positives = 80/155 (51%), Gaps = 3/155 (1%)
 Frame = +2

Query: 45  LTIQFIQSYFVSDYDPTIEDSYTKICTVDGIPARLDILDTAGQEEFGAMREQYMRAGNGF 104
           LT++F+   F+ +Y PT+E  Y     ++    RL+ILDTAGQ  +   +E Y    + F
Sbjct: 2   LTVRFLTRRFIGEYCPTLESVYKYHTVIEDDDVRLEILDTAGQGTY-PWKEGYALWADCF 178

Query: 105 LLVFAINDRQSFNEVGKLFTQILRVKDRDDFPIVLVGNKADLENQRQVLRSEASSFSASH 164
           + V++INDRQS+ E+ ++  Q+  V+       VL  NK DL + RQV + E    +   
Sbjct: 179 VFVYSINDRQSYEELVQVKRQVESVRKSTSLTAVLAANKTDLLHDRQVTQKEGEDLAEEI 358

Query: 165 HMTYFEASAKLRLNVD---EAFEQLVRAVRKYQEQ 196
               +E SA     ++     F  L R  RK+++Q
Sbjct: 359 GCRLYEVSASEGSQMEAITSMFHDLYREFRKHKQQ 463
>08428
          Length = 1109

 Score = 82.4 bits (202), Expect = 1e-16,   Method: Compositional matrix adjust.
 Identities = 51/160 (31%), Positives = 83/160 (51%), Gaps = 1/160 (0%)
 Frame = -3

Query: 42   KSALTIQFIQSYFVSDYDPTIEDSY-TKICTVDGIPARLDILDTAGQEEFGAMREQYMRA 100
            KS++ ++F+   +    + TI  S+ +K   VDG   R  I DTAGQE+F A+   Y R 
Sbjct: 1032 KSSIVLRFVTGSYRPSQESTIGASFMSKSLVVDGAGYRFQIWDTAGQEKFRALAPMYYRG 853

Query: 101  GNGFLLVFAINDRQSFNEVGKLFTQILRVKDRDDFPIVLVGNKADLENQRQVLRSEASSF 160
                ++V+ +   ++F  V K + Q LR     +  + + GNK DLE  R+V+  +A  +
Sbjct: 852  AAAAVIVYDVTRPRTFKSV-KSWIQELRSFGPPNIVLAIAGNKCDLEELREVVEKDAQEY 676

Query: 161  SASHHMTYFEASAKLRLNVDEAFEQLVRAVRKYQEQELPP 200
            ++S    + E SA   +NV+E F +L R        +LPP
Sbjct: 675  ASSISAIFGETSAMTAVNVEEMFTELAR--------QLPP 580
>14456
          Length = 1867

 Score = 82.0 bits (201), Expect = 2e-16,   Method: Compositional matrix adjust.
 Identities = 57/161 (35%), Positives = 88/161 (54%), Gaps = 5/161 (3%)
 Frame = -1

Query: 42   KSALTIQFIQSYFVSDYDPTIEDSY-TKICTVDGIPARLDILDTAGQEEFGAMREQYMRA 100
            KS+L  +F+ + F +    TI   +  K   VD     + I DTAGQE F ++R  + R 
Sbjct: 1102 KSSLMNRFVSNKFDAQSFHTIGVEFLNKDVVVDDETYTMQIWDTAGQERFKSLRTPFYRG 923

Query: 101  GNGFLLVFAINDRQSFNEVGKLFTQILRVKDRDD---FPIVLVGNKADLENQRQVLRSEA 157
             +  LL F+++  QSF  +     + L   D  D   FP V++GNK D+E  RQV   EA
Sbjct: 922  ADCCLLTFSVDSMQSFRNLSMWRKEFLYYADIQDGVTFPFVVLGNKIDVEG-RQVTNEEA 746

Query: 158  SSF-SASHHMTYFEASAKLRLNVDEAFEQLVRAVRKYQEQE 197
             S+ +A+ +  YFE SAK   NV++AF   V+ +R+ ++Q+
Sbjct: 745  RSWCTANSNAPYFETSAKDATNVEKAFLAAVQRLREVEDQQ 623
>33794
          Length = 779

 Score = 71.6 bits (174), Expect = 3e-13,   Method: Compositional matrix adjust.
 Identities = 36/117 (30%), Positives = 64/117 (54%)
 Frame = -1

Query: 72  VDGIPARLDILDTAGQEEFGAMREQYMRAGNGFLLVFAINDRQSFNEVGKLFTQILRVKD 131
           ++G   +L I DT+GQ  F  +   Y R   G +LV+ I ++ SF+ + +   ++   + 
Sbjct: 665 LEGKRVKLQIWDTSGQGRFCTIIRSYSRGAQGIILVYDITNKWSFDGIDRWLKEV--EEH 492

Query: 132 RDDFPIVLVGNKADLENQRQVLRSEASSFSASHHMTYFEASAKLRLNVDEAFEQLVR 188
               P VLVGN+  L  +RQV   +A ++++ ++M+ FE S     N+ E+F +L R
Sbjct: 491 APGIPKVLVGNRLHLAYKRQVAAKQAETYASRNNMSCFEISPLCDFNIRESFCELAR 321
>18509
          Length = 625

 Score = 65.1 bits (157), Expect(2) = 3e-13,   Method: Compositional matrix adjust.
 Identities = 34/70 (48%), Positives = 46/70 (65%)
 Frame = -3

Query: 128 RVKDRDDFPIVLVGNKADLENQRQVLRSEASSFSASHHMTYFEASAKLRLNVDEAFEQLV 187
           RVKD D+ P+VLVGNK DL   R V + +    +  +H+ Y E SAK R  VD+AF  LV
Sbjct: 548 RVKDADEVPMVLVGNKVDLPI-RNVEQRQGKHMAELYHIPYVETSAKTRQGVDDAFYTLV 372

Query: 188 RAVRKYQEQE 197
           R +RKY+E++
Sbjct: 371 REIRKYKERK 342

 Score = 26.6 bits (57), Expect(2) = 3e-13,   Method: Compositional matrix adjust.
 Identities = 11/24 (45%), Positives = 17/24 (70%)
 Frame = -1

Query: 103 GFLLVFAINDRQSFNEVGKLFTQI 126
           GFL VFA+N+ +SF ++ +   QI
Sbjct: 622 GFLCVFAVNNLKSFEDINQYREQI 551
>07465
          Length = 1103

 Score = 70.1 bits (170), Expect = 6e-13,   Method: Compositional matrix adjust.
 Identities = 49/146 (33%), Positives = 72/146 (49%), Gaps = 2/146 (1%)
 Frame = +3

Query: 43  SALTIQFIQSYFVSDYDPTIE-DSYTKICTVDGIPARLDILDTAGQEEFGAMREQYMRAG 101
           S++  ++ +  F  DY  TI  D   +   V G   RL + DTAGQEEF A+ + Y R  
Sbjct: 240 SSMIQRYCKGIFTKDYKKTIGVDFLERQIEVGGEDVRLMLWDTAGQEEFDAITKAYYRGA 419

Query: 102 NGFLLVFAINDRQSFNEVGKLFTQILRVKDR-DDFPIVLVGNKADLENQRQVLRSEASSF 160
              +L F+  DR SF     L T   +V+D   +  +V+V NK DL +   V   EA + 
Sbjct: 420 QACVLAFSTVDRDSFE---ALETWKRKVEDEVGEIGMVIVQNKIDLIDDAVVRPEEAENL 590

Query: 161 SASHHMTYFEASAKLRLNVDEAFEQL 186
           +    + ++  S K  +NVDE F  L
Sbjct: 591 AKKLRLRFYRTSVKENMNVDEVFRYL 668
>01972
          Length = 2359

 Score = 69.7 bits (169), Expect = 9e-13,   Method: Compositional matrix adjust.
 Identities = 34/113 (30%), Positives = 66/113 (58%)
 Frame = +3

Query: 78  RLDILDTAGQEEFGAMREQYMRAGNGFLLVFAINDRQSFNEVGKLFTQILRVKDRDDFPI 137
           + ++ DTAGQE+FG +R+ Y   G   +++F +  R ++  V      ++RV   ++ PI
Sbjct: 450 KFNVWDTAGQEKFGGLRDGYYIQGQCAVIMFDVTSRVTYKNVPNWHRDLVRV--CENIPI 623

Query: 138 VLVGNKADLENQRQVLRSEASSFSASHHMTYFEASAKLRLNVDEAFEQLVRAV 190
           VL GNK D+++++  ++++A  F    ++ Y++ SAK   N ++ F  L R +
Sbjct: 624 VLCGNKVDIKDRK--VKAKAIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKL 776
>33374
          Length = 489

 Score = 68.6 bits (166), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 35/115 (30%), Positives = 63/115 (54%)
 Frame = +1

Query: 67  TKICTVDGIPARLDILDTAGQEEFGAMREQYMRAGNGFLLVFAINDRQSFNEVGKLFTQI 126
           T+   +D    + +I DTAGQE + ++   Y R     ++V+ I ++ +F    K + + 
Sbjct: 145 TQTVCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNQDTFGR-AKTWVKE 321

Query: 127 LRVKDRDDFPIVLVGNKADLENQRQVLRSEASSFSASHHMTYFEASAKLRLNVDE 181
           L+ +   +  I L GNKADL N+R V   EA +++  + + + E SAK  +NV++
Sbjct: 322 LQRQASPNIVIALAGNKADLANKRMVEFEEAQAYAEENSLLFMETSAKTAMNVND 486
>30760
          Length = 596

 Score = 68.2 bits (165), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 41/119 (34%), Positives = 60/119 (50%), Gaps = 1/119 (0%)
 Frame = -1

Query: 79  LDILDTAGQEEFGAMREQYMRAGNGFLLVFAINDRQSFNEVGKLFTQILRVKDRDDFPIV 138
           L + D+AG+E F     ++    +  ++V+ + D  SF+   +   ++   K     P V
Sbjct: 365 LYLFDSAGKEIFSENVTKFWDQPSVVMVVYDVTDETSFSGCVRWLERVRAAKPNTVIPGV 186

Query: 139 LVGNKADLENQRQVLRSEASSFSASHHMTYFEASAKLRLNVDEAFEQLVRAVRK-YQEQ 196
           LV NK DL+ +R+V R E    + SH + YFE SAK   N D  F  L  A  K YQEQ
Sbjct: 185 LVANKTDLDERRRVSRKEGKDLAQSHGLEYFECSAKEMQNTDTPFFCLAHAFHKLYQEQ 9
>06994
          Length = 429

 Score = 60.5 bits (145), Expect(2) = 3e-12,   Method: Compositional matrix adjust.
 Identities = 35/103 (33%), Positives = 47/103 (45%), Gaps = 32/103 (31%)
 Frame = +1

Query: 49  FIQSYFVSDYDPTIEDSYTKICTVDGIPARLDILDTAG---------------------- 86
             + +    YDPTIEDSY K   VDG    L+ILDTAG                      
Sbjct: 115 LCKGFLWKKYDPTIEDSYRKQVEVDGQQCMLEILDTAGTVHASHSNACVHGSLHAFVGTV 294

Query: 87  ----------QEEFGAMREQYMRAGNGFLLVFAINDRQSFNEV 119
                      E+F AMR+ YM+ G GFLL ++I  + +FN++
Sbjct: 295 TPLGRDALLNTEQFTAMRDLYMKNGQGFLLAYSITAQSTFNDL 423

 Score = 27.3 bits (59), Expect(2) = 3e-12,   Method: Compositional matrix adjust.
 Identities = 12/26 (46%), Positives = 15/26 (57%)
 Frame = +3

Query: 30 HKLXXXXXXXXXKSALTIQFIQSYFV 55
          +KL         KSALT+QF+Q  FV
Sbjct: 57 YKLVVLGSGGVGKSALTVQFVQGIFV 134
>33380
          Length = 282

 Score = 64.7 bits (156), Expect = 3e-11,   Method: Compositional matrix adjust.
 Identities = 31/74 (41%), Positives = 45/74 (60%)
 Frame = +3

Query: 77  ARLDILDTAGQEEFGAMREQYMRAGNGFLLVFAINDRQSFNEVGKLFTQILRVKDRDDFP 136
            +L I DTAGQE +  +   Y R   GF+L++ + + +SFN V    TQI +    D+  
Sbjct: 60  VKLQIWDTAGQERYRTITTAYYRGAMGFILMYDVTNEESFNAVQDWCTQI-KTYSWDNAQ 236

Query: 137 IVLVGNKADLENQR 150
           +VLVGNK DLE++R
Sbjct: 237 VVLVGNKCDLEDER 278
>11728
          Length = 635

 Score = 61.6 bits (148), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 35/114 (30%), Positives = 58/114 (50%), Gaps = 1/114 (0%)
 Frame = -1

Query: 42  KSALTIQFIQSYFVSDYDPTIEDSYTKICTVDGIPARLDILDTAGQEEFGAMREQYMRAG 101
           K+ L I +  + F  +Y PT+ D+Y+    VD  P  L + DTAGQE++  +R       
Sbjct: 452 KTCLLISYTTNAFPGEYIPTVFDNYSANVMVDSKPINLGLWDTAGQEDYDRLRPLSYPQT 273

Query: 102 NGFLLVFAINDRQSFNEV-GKLFTQILRVKDRDDFPIVLVGNKADLENQRQVLR 154
           + FL+ F++    SF  V  K + ++       + PI+LVG K DL   ++ + 
Sbjct: 272 DVFLICFSLISPASFENVKAKWYPEVSH--HCPNTPIILVGTKLDLREDKETIE 117
>34359
          Length = 1042

 Score = 59.3 bits (142), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 25/73 (34%), Positives = 45/73 (61%)
 Frame = +3

Query: 78  RLDILDTAGQEEFGAMREQYMRAGNGFLLVFAINDRQSFNEVGKLFTQILRVKDRDDFPI 137
           R ++ DTAGQE+FG +R+ Y   G   +++F +  R ++  V      ++RV   ++ PI
Sbjct: 198 RFNVWDTAGQEKFGGLRDGYYIQGTCAIIMFDVTSRVTYKNVPNWHRDLVRVC--ENIPI 371

Query: 138 VLVGNKADLENQR 150
           VL GNK D+++++
Sbjct: 372 VLCGNKVDIKDRK 410
>34468
          Length = 1502

 Score = 58.9 bits (141), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 50/167 (29%), Positives = 73/167 (43%), Gaps = 2/167 (1%)
 Frame = +1

Query: 42  KSALTIQFIQSYFVSDYDPTIE-DSYTKICTVDGIPARLDILDTAGQEEF-GAMREQYMR 99
           K+ LT +F    F    + TI  D   K   VD    +L + DTAGQE F  +M + Y R
Sbjct: 532 KTCLTYRFCLGKFPDKTEATIGVDFREKSIQVDSEHLKLQLWDTAGQERFRKSMVQHYYR 711

Query: 100 AGNGFLLVFAINDRQSFNEVGKLFTQILRVKDRDDFPIVLVGNKADLENQRQVLRSEASS 159
             +  + V+ +    SF  +     +  R       P +LVGNK D+  +  V  + A  
Sbjct: 712 NVHAVVFVYDMTKMSSFENMPAWIEECDRHNLTKYIPRILVGNKCDVVERIAVNTNLAQK 891

Query: 160 FSASHHMTYFEASAKLRLNVDEAFEQLVRAVRKYQEQELPPSPPSAP 206
           F+ +H+M  FE SAK     D+     V A+      +L  S P  P
Sbjct: 892 FADAHNMPLFETSAK-----DDEKANHVDAIFMTVAHKLKXSKPMMP 1017
>05468
          Length = 1558

 Score = 58.9 bits (141), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 46/153 (30%), Positives = 72/153 (47%), Gaps = 7/153 (4%)
 Frame = -3

Query: 42   KSALTIQFIQSYFVSDYDPTIE-DSYTKICTVDG-IPARLDILDTAGQEEFGAMREQYMR 99
            K+++  +++  +F   Y  TI  D   K+   D     RL + D AGQE FG M   Y +
Sbjct: 1502 KTSIIKRYVHQFFSQHYRATIGVDFALKVLNWDADTLIRLQLWDIAGQERFGNMTRVYYK 1323

Query: 100  AGNGFLLVFAINDRQSFNEVGKLFTQI---LRVKDRDDFPIVLVGNKADLENQRQVLR-S 155
               G  +VF +    +F+ V K    +   +++ D    P VL+ NK D   +  V   S
Sbjct: 1322 EAVGAFVVFDVTRASTFDAVTKWKNDLDSKVQLADGSPVPCVLLANKCDQAKEGLVNNTS 1143

Query: 156  EASSF-SASHHMTYFEASAKLRLNVDEAFEQLV 187
            +   F S    + ++E SAK  +N+DEA   LV
Sbjct: 1142 QMDEFCSEKGFIGWYETSAKENINIDEAARFLV 1044
>19006
          Length = 568

 Score = 57.0 bits (136), Expect = 6e-09,   Method: Compositional matrix adjust.
 Identities = 36/113 (31%), Positives = 55/113 (48%)
 Frame = -2

Query: 42  KSALTIQFIQSYFVSDYDPTIEDSYTKICTVDGIPARLDILDTAGQEEFGAMREQYMRAG 101
           K+ L I F +  F   Y PT+ ++Y     VD     L + DTAGQE++  +R       
Sbjct: 399 KTCLLIVFSKDQFPEVYVPTVFENYVADIEVDSKQVELALWDTAGQEDYDRLRPLSYPDT 220

Query: 102 NGFLLVFAINDRQSFNEVGKLFTQILRVKDRDDFPIVLVGNKADLENQRQVLR 154
           +  L+ F+I+   S   + + +T  +R     + PI+LVGNK DL N     R
Sbjct: 219 DVILMCFSIDSPDSLENIPEKWTPEVR-HFCPNVPIILVGNKKDLRNDENTKR 64
>12339
          Length = 578

 Score = 55.8 bits (133), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 38/141 (26%), Positives = 70/141 (49%), Gaps = 12/141 (8%)
 Frame = -2

Query: 87  QEEFGAMREQYMRAGNGFLLVFAINDRQSFNEVGKLFTQILRV---KDRDDFPIVLVGNK 143
           QE F ++   + R  +  +LV+ + + ++F+ +     + L     +D + FP V++GNK
Sbjct: 577 QERFQSLGVAFYRGADCCILVYDVTEXKTFDSLDSWQREFLNQASPRDPEHFPFVVIGNK 398

Query: 144 ADLENQRQVLRSEASSFSASHHMTYFEASAKLRLNVDEAFEQLVR-AVRKYQEQELPPSP 202
            DL+N+    +      S    + YFE SAK  +NV++AF+ + + A+ +  E E+   P
Sbjct: 397 IDLDNRVVTAKRGQGWCSTKGGIPYFETSAKEAINVEQAFQTVAKNALAQESEVEIDDFP 218

Query: 203 P--------SAPRKKDGGCPC 215
                    S PR++   C C
Sbjct: 217 SEIRLSNDDSRPRER---CAC 164
>19656
          Length = 428

 Score = 54.7 bits (130), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 28/86 (32%), Positives = 46/86 (53%), Gaps = 1/86 (1%)
 Frame = +3

Query: 42  KSALTIQFIQSYFVSDYDPTIEDSYTKICTVDGIPARLDILDTAGQEEFGAMREQYMRAG 101
           K+ L I +  + F  +Y PT+ D+Y+    VDG P  L + DTAGQE++  +R       
Sbjct: 150 KTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGRPVNLGLWDTAGQEDYDRLRPLSYPQT 329

Query: 102 NGFLLVFAINDRQSFNEV-GKLFTQI 126
           + FLL F++    SF  +  K + ++
Sbjct: 330 DVFLLCFSVASPASFENIRAKWYPEV 407
>13750
          Length = 503

 Score = 54.3 bits (129), Expect = 4e-08,   Method: Compositional matrix adjust.
 Identities = 38/159 (23%), Positives = 72/159 (45%), Gaps = 6/159 (3%)
 Frame = -2

Query: 42  KSALTIQFIQSYFVSDYDPTIEDSYTKICT------VDGIPARLDILDTAGQEEFGAMRE 95
           K+ L  ++ + +F+    PTI      +C+       D +  R  + DT G E + ++  
Sbjct: 502 KTCLLRRYQKGFFMDRTMPTI----AVLCSEFNESRTDPLNVRYTLWDTGGAETYRSLWV 335

Query: 96  QYMRAGNGFLLVFAINDRQSFNEVGKLFTQILRVKDRDDFPIVLVGNKADLENQRQVLRS 155
            + R     LLV+ +    SF     ++ + L +K+  +  ++ VG+K DLE  R +   
Sbjct: 334 SHFRGAQVALLVYDVTCEWSFLTATTVWRKAL-MKNIPEAQVIFVGSKTDLEENRVISTE 158

Query: 156 EASSFSASHHMTYFEASAKLRLNVDEAFEQLVRAVRKYQ 194
              +F+     T+FE S+    NVD  F ++   + + Q
Sbjct: 157 RGQAFATQCGYTFFETSSVTGKNVDAVFWEIAFILARLQ 41
>01398
          Length = 1421

 Score = 54.3 bits (129), Expect = 4e-08,   Method: Compositional matrix adjust.
 Identities = 28/102 (27%), Positives = 53/102 (51%)
 Frame = -2

Query: 87   QEEFGAMREQYMRAGNGFLLVFAINDRQSFNEVGKLFTQILRVKDRDDFPIVLVGNKADL 146
            QE F ++   Y R   G ++V+ I  R +F  + + + +     +      +++G+K+D 
Sbjct: 1420 QERFRSITRSYYRNSVGVIIVYDITKRSTFENLKQWYEEARNHIEPHKAIFLVLGHKSDR 1241

Query: 147  ENQRQVLRSEASSFSASHHMTYFEASAKLRLNVDEAFEQLVR 188
            E+ RQV   E   F+  H + +FE SAK   N+++ F Q+ +
Sbjct: 1240 EDARQVTAREGRRFAEMHGLKFFETSAKSGHNIEDVFAQIAK 1115
>17511
          Length = 483

 Score = 53.5 bits (127), Expect = 7e-08,   Method: Compositional matrix adjust.
 Identities = 35/109 (32%), Positives = 55/109 (50%), Gaps = 4/109 (3%)
 Frame = -3

Query: 42  KSALTIQFIQSYFVSDYDPTI-EDSYTKICTVDGIPARLDILDTAGQEEFGAMREQYMRA 100
           K++L  Q++   F + Y  TI  D  TK   VD     + I DTAGQE F ++   + R 
Sbjct: 328 KTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQIWDTAGQERFQSLGVAFYRG 149

Query: 101 GNGFLLVFAINDRQSFNEVGKLFTQIL---RVKDRDDFPIVLVGNKADL 146
            +  +LVF +    +F  +     + L     +D ++FP V++GNK DL
Sbjct: 148 ADCCVLVFDVTMPNTFRSLDSWRDEFLIQASPRDPENFPFVVIGNKIDL 2
>13745
          Length = 1045

 Score = 52.8 bits (125), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 37/117 (31%), Positives = 62/117 (52%), Gaps = 5/117 (4%)
 Frame = +2

Query: 87  QEEFGAMREQYMRAGNGFLLVFAINDRQSFNEVGKLFTQIL---RVKDRDDFPIVLVGNK 143
           QE F ++   + R  +  +LV+ +    SF  +     + L     +D + FP V++GNK
Sbjct: 2   QERFQSLGVAFYRGADCCVLVYDVTAPNSFKNLDSWRDEFLIQASPRDPEHFPFVVLGNK 181

Query: 144 ADLENQRQVLRSEASSFSASHH-MTYFEASAKLRLNVDEAFEQLVR-AVRKYQEQEL 198
            DL+N RQV    A  +  S + + Y+E SAK  +NV+ AF+ + + A+ +  E EL
Sbjct: 182 VDLDN-RQVSTRRAQQWCQSKNDIPYYETSAKEGINVEMAFQTIAKNALEQETEAEL 349
>31291
          Length = 446

 Score = 52.4 bits (124), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 39/123 (31%), Positives = 56/123 (45%), Gaps = 13/123 (10%)
 Frame = -1

Query: 79  LDILDTAGQEEFGAMREQYMRAGNGFLLVFAINDRQSFNEVGKLFTQILRVKDRDDFPIV 138
           L + DTAGQE++  +R       + F+L F++    S   V   +   +R  D    PIV
Sbjct: 446 LQLWDTAGQEDYDRLRPLAYPNTDVFMLXFSLMSEASMKNVKVKWYPEIRHHD-PHVPIV 270

Query: 139 LVGNKADLENQRQVLRSEASS-------------FSASHHMTYFEASAKLRLNVDEAFEQ 185
           LVG K DL   ++ +R   SS               A     YFE S+K + N+  AFE+
Sbjct: 269 LVGTKLDLRQDKEAVRKLRSSRQDPVSSNQGNDLAKAIKAKRYFECSSKTQENLKTAFEE 90

Query: 186 LVR 188
            VR
Sbjct: 89  TVR 81
>26083
          Length = 432

 Score = 49.7 bits (117), Expect = 8e-07,   Method: Compositional matrix adjust.
 Identities = 33/103 (32%), Positives = 55/103 (53%), Gaps = 1/103 (0%)
 Frame = +1

Query: 42  KSALTIQFIQSYFVSDYDPTIE-DSYTKICTVDGIPARLDILDTAGQEEFGAMREQYMRA 100
           K++L  +F+   F + Y  TI  D  +K   ++    RL + DTAGQE F ++   Y+R 
Sbjct: 115 KTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTIRLQLWDTAGQERFRSLIPSYIRD 294

Query: 101 GNGFLLVFAINDRQSFNEVGKLFTQILRVKDRDDFPIVLVGNK 143
            +  ++V+ I +  SF++  K    + R +   D  I+LVGNK
Sbjct: 295 SSVAVVVYDITNANSFHQTSKWIDDV-RTERGSDVIIMLVGNK 420
>10708
          Length = 2775

 Score = 40.4 bits (93), Expect(2) = 4e-06,   Method: Compositional matrix adjust.
 Identities = 29/93 (31%), Positives = 43/93 (46%), Gaps = 13/93 (13%)
 Frame = -3

Query: 134  DFPIVLVGNKADLEN----QRQVLR--------SEASSFSAS-HHMTYFEASAKLRLNVD 180
            + PI+LVGNK DL N    +R++++         E  + S   +  +Y E SAK +  V 
Sbjct: 2554 NVPIILVGNKKDLRNDENTKRELMKMKQEPVRLDEGRAMSEKINAYSYLECSAKTKEGVR 2375

Query: 181  EAFEQLVRAVRKYQEQELPPSPPSAPRKKDGGC 213
            E FE   RA  + +            +KK GGC
Sbjct: 2374 EVFETATRAALQTK------------KKKKGGC 2312

 Score = 26.6 bits (57), Expect(2) = 4e-06,   Method: Compositional matrix adjust.
 Identities = 12/41 (29%), Positives = 21/41 (51%)
 Frame = -2

Query: 79   LDILDTAGQEEFGAMREQYMRAGNGFLLVFAINDRQSFNEV 119
            L + DTAGQE++  +R       +  L+ F+I+   S   +
Sbjct: 2717 LALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENI 2595
>01095
          Length = 1745

 Score = 47.4 bits (111), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 26/87 (29%), Positives = 49/87 (56%)
 Frame = -1

Query: 106  LVFAINDRQSFNEVGKLFTQILRVKDRDDFPIVLVGNKADLENQRQVLRSEASSFSASHH 165
            +V+ I ++ +F    K + + L+ +   +  I L GNKADL N+R V   EA +++  + 
Sbjct: 1745 VVYDITNQDTFGR-AKTWVKELQRQASPNIVIALAGNKADLANKRMVEFEEAQAYAEENS 1569

Query: 166  MTYFEASAKLRLNVDEAFEQLVRAVRK 192
            + + E SAK  +NV++ F  + + + K
Sbjct: 1568 LLFMETSAKTAMNVNDIFLAIAKKLPK 1488
>31928
          Length = 429

 Score = 47.0 bits (110), Expect = 7e-06,   Method: Compositional matrix adjust.
 Identities = 26/87 (29%), Positives = 47/87 (54%), Gaps = 4/87 (4%)
 Frame = +2

Query: 61  TIEDSYTKICTVD-GIPARLDILDTAG---QEEFGAMREQYMRAGNGFLLVFAINDRQSF 116
           TIED YT +   D G+  ++ I DT     +   G + + Y+   +GF+LV+     +SF
Sbjct: 53  TIEDIYTAVIETDRGVKEKVRIFDTGAAALETTEGDLPKHYLNFPDGFVLVYDTTSWESF 232

Query: 117 NEVGKLFTQILRVKDRDDFPIVLVGNK 143
             + KL   I + +D+ +  ++++GNK
Sbjct: 233 RRLDKLKKDIDKHRDKREVHMIVIGNK 313
>32723
          Length = 384

 Score = 46.6 bits (109), Expect = 9e-06,   Method: Compositional matrix adjust.
 Identities = 27/97 (27%), Positives = 49/97 (50%)
 Frame = +2

Query: 87  QEEFGAMREQYMRAGNGFLLVFAINDRQSFNEVGKLFTQILRVKDRDDFPIVLVGNKADL 146
           QE F ++ + Y R+ N  +LV+ +  +QS+  + +   +I  +         LVGNK D 
Sbjct: 2   QERFRSITQSYYRSANALILVYDVCSQQSYESLPQWIHEI-ELYAGTKVLAFLVGNKIDQ 178

Query: 147 ENQRQVLRSEASSFSASHHMTYFEASAKLRLNVDEAF 183
            ++R++       F+  + M + E SAK   NV++ F
Sbjct: 179 TDKREIPTHIGKEFAERYEMRFLETSAKEADNVEKLF 289
>25618
          Length = 475

 Score = 42.7 bits (99), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 31/96 (32%), Positives = 47/96 (48%), Gaps = 7/96 (7%)
 Frame = +3

Query: 127 LRVKDRDDFPIVLVGNKADLENQ-RQVLRSEASSFSASHHMTYFEASAKLRLNVDEAFEQ 185
           LR ++     IVL GNKADL ++ R V   +A +F+  + + + E SAK  + V E F  
Sbjct: 54  LRQQNAGSVLIVLAGNKADLASEHRAVSADDARTFAEDNGLIFAEVSAKTGMAVSEVFMT 233

Query: 186 LV-RAVRKYQE-----QELPPSPPSAPRKKDGGCPC 215
           +  + VR+ +E     Q       S   +  GGC C
Sbjct: 234 IAHKLVRRAEEGQGSXQGRERVRLSEAEEASGGCKC 341
>34597
          Length = 773

 Score = 42.7 bits (99), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 21/78 (26%), Positives = 42/78 (53%)
 Frame = -2

Query: 113 RQSFNEVGKLFTQILRVKDRDDFPIVLVGNKADLENQRQVLRSEASSFSASHHMTYFEAS 172
           ++SF  + K    I    + +D   +++GNK D+ ++R V +    + +  H + + E S
Sbjct: 715 KKSFENIVKWLRNIDEHAN-EDVEKMILGNKCDMTDKRVVSKERGEAIAREHSIRFMETS 539

Query: 173 AKLRLNVDEAFEQLVRAV 190
           AK  +N++ AF +L  A+
Sbjct: 538 AKSNINIERAFCELAEAI 485
>08153
          Length = 1703

 Score = 38.9 bits (89), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 20/68 (29%), Positives = 32/68 (47%)
 Frame = +1

Query: 81  ILDTAGQEEFGAMREQYMRAGNGFLLVFAINDRQSFNEVGKLFTQILRVKDRDDFPIVLV 140
           + D  GQ++   +   Y +   G + V   NDR+  NE  +   ++L   D  D  I++ 
Sbjct: 226 VWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERINEAKEELARMLNEDDLRDAIILVF 405

Query: 141 GNKADLEN 148
            NK DL N
Sbjct: 406 ANKQDLPN 429
>14119
          Length = 602

 Score = 37.4 bits (85), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 25/75 (33%), Positives = 42/75 (56%), Gaps = 2/75 (2%)
 Frame = +1

Query: 123 FTQILRVKDRDDFPIVLVGNKADLENQ-RQVLRSEASSFSASHHMTYFEASAKLRLNVDE 181
           + + LR ++     IVL GNKADL ++ R V   +A +F+  + + + E SAK  + V E
Sbjct: 22  WVKELRQQNAGSVLIVLAGNKADLASEHRAVSADDARTFAEDNGLIFAEVSAKTGMAVSE 201

Query: 182 AFEQLV-RAVRKYQE 195
            F  +  + VR+ +E
Sbjct: 202 VFMTIAHKLVRRAEE 246
>35581
          Length = 364

 Score = 35.4 bits (80), Expect = 0.019,   Method: Compositional matrix adjust.
 Identities = 14/42 (33%), Positives = 23/42 (54%)
 Frame = +2

Query: 67  TKICTVDGIPARLDILDTAGQEEFGAMREQYMRAGNGFLLVF 108
           T +    G+ A +D+ DTAGQE + ++   Y R     L+V+
Sbjct: 164 TTVTLTSGVMASVDLWDTAGQERYRSLTSSYYRDTKAVLIVY 289
>00552
          Length = 455

 Score = 34.7 bits (78), Expect = 0.031,   Method: Compositional matrix adjust.
 Identities = 13/47 (27%), Positives = 27/47 (57%)
 Frame = -3

Query: 81  ILDTAGQEEFGAMREQYMRAGNGFLLVFAINDRQSFNEVGKLFTQIL 127
           I DTAGQE + ++R  + R  +  LL F++++ +S   +   + + +
Sbjct: 147 IWDTAGQERYKSLRTPFYRGTDCCLLTFSVDNLKSLQSLSDWYDEFV 7
>09700
          Length = 1855

 Score = 33.5 bits (75), Expect = 0.066,   Method: Compositional matrix adjust.
 Identities = 23/78 (29%), Positives = 36/78 (46%), Gaps = 12/78 (15%)
 Frame = -1

Query: 136  PIVLVGNKADLENQRQVL------------RSEASSFSASHHMTYFEASAKLRLNVDEAF 183
            P+VLVG ++DL N  +VL              +AS  +     +Y E SA  + N+ E F
Sbjct: 1813 PLVLVGTQSDLRNDVKVLIELAKYKEKPVSEDDASKLAHQLGASYVECSALTQKNLKEMF 1634

Query: 184  EQLVRAVRKYQEQELPPS 201
            +  +    ++ E EL  S
Sbjct: 1633 DSCILTSLQWAEAELQRS 1580
>18949
          Length = 414

 Score = 31.6 bits (70), Expect = 0.24,   Method: Compositional matrix adjust.
 Identities = 15/64 (23%), Positives = 29/64 (45%)
 Frame = +3

Query: 82  LDTAGQEEFGAMREQYMRAGNGFLLVFAINDRQSFNEVGKLFTQILRVKDRDDFPIVLVG 141
            D  G  +   + + Y  A +G + +  ++D +   E       +LR     D P++++G
Sbjct: 72  FDLGGHRQARRVWKDYFPAVDGIVFIVDVHDTERITEAKAELDSLLRDDQIADIPVLVLG 251

Query: 142 NKAD 145
           NK D
Sbjct: 252 NKMD 263
>09827
          Length = 1201

 Score = 31.6 bits (70), Expect = 0.28,   Method: Compositional matrix adjust.
 Identities = 16/66 (24%), Positives = 31/66 (46%)
 Frame = -3

Query: 81  ILDTAGQEEFGAMREQYMRAGNGFLLVFAINDRQSFNEVGKLFTQILRVKDRDDFPIVLV 140
           + D  GQ++   +   Y +   G + V   ND++   E  +  T++L   +  D  +++ 
Sbjct: 971 VWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDKERVQEAREELTRMLNEDELRDAVLLVF 792

Query: 141 GNKADL 146
            NK DL
Sbjct: 791 ANKQDL 774
>32770
          Length = 387

 Score = 31.2 bits (69), Expect = 0.35,   Method: Compositional matrix adjust.
 Identities = 20/73 (27%), Positives = 30/73 (41%), Gaps = 7/73 (9%)
 Frame = +2

Query: 132 RDDFPIVLVGNKADLENQRQVLRSEASSFSASHHMT-------YFEASAKLRLNVDEAFE 184
           R   P +LVG +ADL +  Q    +         +        YFE SA +   +D  F 
Sbjct: 20  RPGTPFILVGTQADLRHHSQPASKDMVPAHKGKKLARKVGALGYFECSALIGSGLDRVFR 199

Query: 185 QLVRAVRKYQEQE 197
           Q+V      Q++E
Sbjct: 200 QVVTCAVHPQKRE 238
>11378
          Length = 1688

 Score = 28.5 bits (62), Expect = 2.2,   Method: Compositional matrix adjust.
 Identities = 15/68 (22%), Positives = 31/68 (45%)
 Frame = +3

Query: 78  RLDILDTAGQEEFGAMREQYMRAGNGFLLVFAINDRQSFNEVGKLFTQILRVKDRDDFPI 137
           R    D  G  +   + + Y  A +G + +  ++DR+   E       ++  +   + PI
Sbjct: 456 RFTTFDLGGHRQARRVWKDYFPAVDGIVFLVDVHDRERLVEAKAELDSLMTDEQVANAPI 635

Query: 138 VLVGNKAD 145
           +++GNK D
Sbjct: 636 LVLGNKID 659
>15662
          Length = 455

 Score = 27.7 bits (60), Expect = 3.4,   Method: Compositional matrix adjust.
 Identities = 13/51 (25%), Positives = 27/51 (52%)
 Frame = +2

Query: 95  EQYMRAGNGFLLVFAINDRQSFNEVGKLFTQILRVKDRDDFPIVLVGNKAD 145
           + Y  A +G + +  ++DR+ F E       ++  +   + PI+++GNK D
Sbjct: 20  KDYFPAVDGIVFLVDVHDRERFVEAKAELDSLMTDEQVANAPILVLGNKID 172
>25655
          Length = 871

 Score = 26.6 bits (57), Expect = 7.5,   Method: Compositional matrix adjust.
 Identities = 11/18 (61%), Positives = 14/18 (77%)
 Frame = -2

Query: 178 NVDEAFEQLVRAVRKYQE 195
            VD+AF  LVR +RKY+E
Sbjct: 810 RVDDAFYTLVREIRKYKE 757
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|7305255|ref|NP_038959.1| mitogen-activated protein
kinase 8 interacting protein 3 [Mus musculus]
         (1337 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

28675                                                                 154   2e-37
28306                                                                  84   4e-16
35108                                                                  75   1e-13
20186                                                                  71   2e-12
26951                                                                  54   4e-07
16877                                                                  32   2.2  
23337                                                                  32   2.2  
25554                                                                  30   7.0  
>28675
          Length = 596

 Score =  154 bits (389), Expect = 2e-37,   Method: Compositional matrix adjust.
 Identities = 72/109 (66%), Positives = 82/109 (75%), Gaps = 1/109 (0%)
 Frame = +2

Query: 966  SSAAPTMWLGAQNGWLYVHSAVANWKKCLHSIKLKDSVLSLVHVKGRVLVALADGTLAIF 1025
            SSA PTMW+G Q+G LYVHSAV  W++CLHS+KLKDS+L +VHVKGRV VALADGT+AIF
Sbjct: 140  SSALPTMWMGGQSGSLYVHSAVTQWRRCLHSVKLKDSILGIVHVKGRVFVALADGTVAIF 319

Query: 1026 HRGEDGQWDLSNYHLMDLGHPHHSIRCMAVVND-RVWCGYKNKVHVIQP 1073
            HRG  G    +       G P  SIRCM VV D RVWCGYKNKVH+I P
Sbjct: 320  HRGGRGSVGPAQLPYPGPGAPKSSIRCMTVVADSRVWCGYKNKVHIISP 466

 Score = 86.3 bits (212), Expect = 8e-17,   Method: Compositional matrix adjust.
 Identities = 47/101 (46%), Positives = 53/101 (52%), Gaps = 3/101 (2%)
 Frame = +3

Query: 1010 KGRVLVALADGTLAIFHRGEDGQWDLSNYHLMDLGHPHHSIRC---MAVVNDRVWCGYKN 1066
            +G  L     G       G +GQWDL NYH++DLG P            V        K 
Sbjct: 273  RGECLWL*LTGQWPYSTEGAEGQWDLLNYHILDLGRPSPPSGA*PWWPTVASGA--ATKT 446

Query: 1067 KVHVIQPKTMQIEKSFDAHPRRESQVRQLAWIGDGVWVSIR 1107
            K     P  M IEK FDAHPR+ESQVRQL W+GDGVWVSIR
Sbjct: 447  KCTSSLPTDMSIEKQFDAHPRKESQVRQLCWVGDGVWVSIR 569
>28306
          Length = 373

 Score = 84.0 bits (206), Expect = 4e-16,   Method: Composition-based stats.
 Identities = 41/119 (34%), Positives = 68/119 (57%), Gaps = 5/119 (4%)
 Frame = -2

Query: 1059 RVWCGYKNKVHVIQPKTMQIEKSFDAHPRRESQVRQLAWIGDGVWVSIRLDSTLRLYHAH 1118
            ++WCG +N +HVI P  +  E SF         V+ +   G GVWV+ +  S + L+HA 
Sbjct: 372  KLWCGCQNSIHVINPLALNTELSFQVMSDPNRTVQCMVCCGQGVWVACQHSSKISLFHAT 193

Query: 1119 THQHLQDVDIEPYVSKMLGTG-----KLGFSFVRITALLIAGNRLWVGTGNGVVISIPL 1172
            T++ L +V +   VS+ L +      +   + +RITALL+  + LWVGT  GV++++P+
Sbjct: 192  TYEFLLEVSVAQAVSQKLQSADDIIRQHKAACLRITALLVCKDLLWVGTSAGVILTVPI 16
>35108
          Length = 358

 Score = 75.5 bits (184), Expect = 1e-13,   Method: Composition-based stats.
 Identities = 48/110 (43%), Positives = 60/110 (54%)
 Frame = -2

Query: 1224 CSMAQAQLCFHGHRDAVKFFVSVPGNVLATLNGSVLXXXXXXXXXXXXXXXXXGQKLKNA 1283
            C MA AQL FHGHRDAVKFFVSVP  +L   NG +                       + 
Sbjct: 357  CCMANAQLSFHGHRDAVKFFVSVP--MLQQPNGVLTFTNXR----------------PDM 232

Query: 1284 LVLSGGEGYIDFRIGDGEDDETEECAGDVNQTKPSLSKAERSHIIVWQVS 1333
            LV+ GGEGYIDFRI D  +D       + NQT    ++ ++S++IVW VS
Sbjct: 231  LVMCGGEGYIDFRIND--NDMENSIQLEPNQTIE--NRGDKSYLIVWHVS 94
>20186
          Length = 792

 Score = 71.2 bits (173), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 38/126 (30%), Positives = 68/126 (53%), Gaps = 3/126 (2%)
 Frame = +1

Query: 1050 IRCMAVVNDRVWCGYKNKVHVIQPKTMQIEKSFDAHPRRESQVRQLAWIGDGVWVSIRLD 1109
            ++C  VV D +W      VH+IQ  +++          RE+ V Q+   G G+WV+    
Sbjct: 25   VKCQVVVEDDLWIACGRHVHIIQIDSLKTRIKHQLSGDRETSVLQMVRSGVGMWVAFHHS 204

Query: 1110 STLRLYHAHTHQHLQDVDIEPYVSKMLGTGKLGFSFVR---ITALLIAGNRLWVGTGNGV 1166
            + +RL+H  T ++LQ++ +   V+++L   K G S  R   +T +  +   LWVGT  G+
Sbjct: 205  AAVRLFHLETMENLQEMSVANTVNRVLAE-KSGSSETRDCVVTCIAASTGLLWVGTSVGL 381

Query: 1167 VISIPL 1172
            ++++PL
Sbjct: 382  ILTLPL 399
>26951
          Length = 463

 Score = 53.9 bits (128), Expect = 4e-07,   Method: Compositional matrix adjust.
 Identities = 33/55 (60%), Positives = 47/55 (85%)
 Frame = +1

Query: 130 EFQTRQLELKAKNYADQISRLEERESEMKKEYNALHQRHTEMIQTYVEHIERSKM 184
           E   R LELKAKN AD +SRLEE+ESEMKKEY+ LH+R+TE+ +T+++++ER+K+
Sbjct: 10  ESVVRMLELKAKNSADHVSRLEEKESEMKKEYSKLHERYTELFKTHMDYMERTKI 174
>16877
          Length = 823

 Score = 31.6 bits (70), Expect = 2.2,   Method: Composition-based stats.
 Identities = 18/57 (31%), Positives = 26/57 (45%)
 Frame = +2

Query: 1036 SNYHLMDLGHPHHSIRCMAVVNDRVWCGYKNKVHVIQPKTMQIEKSFDAHPRRESQV 1092
            S YHL+ +G  +  I+ +    DR W   KNK     P  M  E   +  P  +SQ+
Sbjct: 353  SWYHLLLVGCTNKYIKSIVKFRDRTW---KNKTEETSPGDMSTEAGLNTGPLFKSQL 514
>23337
          Length = 979

 Score = 31.6 bits (70), Expect = 2.2,   Method: Composition-based stats.
 Identities = 18/57 (31%), Positives = 26/57 (45%)
 Frame = -3

Query: 1036 SNYHLMDLGHPHHSIRCMAVVNDRVWCGYKNKVHVIQPKTMQIEKSFDAHPRRESQV 1092
            S YHL+ +G  +  I+ +    DR W   KNK     P  M  E   +  P  +SQ+
Sbjct: 572  SWYHLLLVGCTNKYIKSIVKFRDRTW---KNKTEETSPGDMSTEAGLNTGPLFKSQL 411
>25554
          Length = 435

 Score = 30.0 bits (66), Expect = 7.0,   Method: Composition-based stats.
 Identities = 16/43 (37%), Positives = 20/43 (46%), Gaps = 5/43 (11%)
 Frame = -2

Query: 1025 FHRGEDGQWDLSNYHLMDLGHP-----HHSIRCMAVVNDRVWC 1062
            FH+G  GQW L  +HL D         HH   C ++   R WC
Sbjct: 149  FHQGPVGQWRL*RHHLCDRAKT*RRLYHH---CNSLQRTRGWC 30
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|88853578|ref|NP_031480.2| adaptor protein complex
AP-1, beta 1 subunit [Mus musculus]
         (943 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

31995                                                                 154   2e-37
19476                                                                 126   5e-29
27755                                                                 117   2e-26
18633                                                                  87   3e-17
31255                                                                  38   0.023
22573                                                                  30   3.6  
>31995
          Length = 1263

 Score =  154 bits (388), Expect = 2e-37,   Method: Compositional matrix adjust.
 Identities = 84/237 (35%), Positives = 145/237 (61%), Gaps = 1/237 (0%)
 Frame = -2

Query: 288  LVTLLSAEPELQYVALRNINLIVQKRPEILKHEMKVFFVKYNDPIYVKLEKLDIMIRLAS 347
            L+ LL +  E+QYV L ++  +  KR  + +  +K F+V+ +DP+++KL KL+I+  LA+
Sbjct: 1262 LIRLLRSHQEIQYVVLSDVATMTTKRKGMFEPYLKSFYVRSSDPLHIKLLKLEILTNLAT 1083

Query: 348  QANIAQVLAELKEYATEVDVDFVRKAVRAIGRCAIKVEQSAERCVSTLLDLIQTKVNYVV 407
            + NI+ +L E + Y T  D +F    ++AIGRCA  + +  + C++ L+ L+  +   VV
Sbjct: 1082 ETNISTILREFQTYVTSSDKEFAAATIQAIGRCASSICEVTDTCLNGLVHLMSNRBEAVV 903

Query: 408  QEAIVVIKDIFRKYPNKYESVIATLCENLDSLDEPEARAAMIWIVGEYAERIDN-ADELL 466
             E++VVIK + +  PN+++ +I  +   +D +  P ARA+++W++GEY+ER+   A ++L
Sbjct: 902  AESVVVIKKLLQMRPNEHKGIICHMARMVDKITVPMARASILWLIGEYSERVPKIAPDVL 723

Query: 467  ESFLEGFHDESTQVQLQLLTAIVKLFLKKPTETQELVQQVLSLATQDSDNPDLRDRG 523
                + F  E   V+LQ+L    KL +  P +T+ L Q VL+LA  D  N D+RDR 
Sbjct: 722  RKLAKSFTSEEDIVKLQVLNLATKLCITNPKQTKLLCQYVLNLAKYD-QNYDIRDRS 555
>19476
          Length = 428

 Score =  126 bits (316), Expect = 5e-29,   Method: Compositional matrix adjust.
 Identities = 57/104 (54%), Positives = 79/104 (75%)
 Frame = +1

Query: 840 RQMFLATWKDIANENEAQFQIRDCPLNTEAASNKLQSSNIFTVAKRNVEGQDMLYQSLKL 899
           +++FL TWK+I   NE Q+ +      T+  ++K+ ++NIFT+AKRNVEGQDMLYQSLKL
Sbjct: 1   KRVFLNTWKEIPAANELQYSLSGVIGTTDGIASKMTTNNIFTIAKRNVEGQDMLYQSLKL 180

Query: 900 TNGIWVLAELRIQPGNPSFTLSLKCRAPEVSQHVYQAYETILKN 943
           TN IWVL EL++QPGNP  TLSLK R+ EV+  ++ AYE I+++
Sbjct: 181 TNNIWVLLELKLQPGNPEATLSLKSRSVEVAYIIFAAYEIIIRS 312
>27755
          Length = 510

 Score =  117 bits (292), Expect = 2e-26,   Method: Compositional matrix adjust.
 Identities = 62/108 (57%), Positives = 76/108 (70%)
 Frame = -2

Query: 696 LSDLFDLTSGVGTLSGSYVAPKAVWLPAMKAKGLEISGTFTRQAGSISMDLQLTNKALQV 755
           L D+F L SG  +LS     PK +WLPA K KGLEI GTF+R+ G I MD+ LTNKA+Q 
Sbjct: 317 LGDIFGL-SGT-SLSVGVQIPKVIWLPAEKGKGLEILGTFSRRNGEIYMDMTLTNKAMQP 144

Query: 756 MTDFAIQFNRNSFGLAPAAPLQVHVPLSPNQTVEISLPLNTVGSVLKM 803
            T+FAIQ N+NSFGL PA+PLQ   PL PNQT++ SL L T G + +M
Sbjct: 143 XTNFAIQLNKNSFGLVPASPLQAP-PLPPNQTIDDSLALGTTGPIQRM 3
>18633
          Length = 404

 Score = 87.0 bits (214), Expect = 3e-17,   Method: Compositional matrix adjust.
 Identities = 40/46 (86%), Positives = 43/46 (93%)
 Frame = +2

Query: 48  SALFPDVVNCMQTDNLELKKLVYLYLMNYAKSQPDMAIMAVNTFVK 93
           SALF DVVNCMQT+NLELKKLVYLYLMNYAKSQ D AI++VNTFVK
Sbjct: 161 SALFTDVVNCMQTENLELKKLVYLYLMNYAKSQSDTAIISVNTFVK 298
>31255
          Length = 401

 Score = 37.7 bits (86), Expect = 0.023,   Method: Composition-based stats.
 Identities = 19/85 (22%), Positives = 47/85 (55%)
 Frame = +2

Query: 389 ERCVSTLLDLIQTKVNYVVQEAIVVIKDIFRKYPNKYESVIATLCENLDSLDEPEARAAM 448
           E   + L++L+ T   +V+   + V++ +  K    +  +I  +C++  S+ + +A+AAM
Sbjct: 89  EASEAKLVNLMDTTSLHVLSNLVCVVQSMNIKDDRFWXKLIRPICQHFQSVTDHQAKAAM 268

Query: 449 IWIVGEYAERIDNADELLESFLEGF 473
           ++I+G++     +   +LE  ++ F
Sbjct: 269 LFIIGQHLTHSTDTFSILEECVDNF 343
>22573
          Length = 755

 Score = 30.4 bits (67), Expect = 3.6,   Method: Composition-based stats.
 Identities = 11/33 (33%), Positives = 18/33 (54%)
 Frame = -2

Query: 549 SEETDLIEPTLLDELICYIGTLASVYHKPPNAF 581
           +  +D + PTL D  IC +G   S+++ P   F
Sbjct: 652 ARRSDFVGPTLTDFFICPVGQAGSIFYLPDTLF 554
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|139948818|ref|NP_598508.2| hypothetical protein
LOC72722 [Mus musculus]
         (515 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

28114                                                                 152   3e-37
>28114
          Length = 845

 Score =  152 bits (384), Expect = 3e-37,   Method: Compositional matrix adjust.
 Identities = 72/156 (46%), Positives = 107/156 (68%)
 Frame = +1

Query: 149 ICIALGMSKPPANITMFQFFSGIEKKLKETLAKVPPNHVGKPLLKKPMGPAHWEKIEAIN 208
           + + LG ++PP NIT FQ FS +E K+KE + +  P   GK LLK  +    W+ +  +N
Sbjct: 355 MLMGLGFARPPDNITAFQLFSKLEAKVKELMGQ-HPGQTGKSLLKARLSDKQWDHVMDVN 531

Query: 209 QAIANEYEVRRKLLIKRLDVTVQSFGWSDRAKSQTDKLAKVYQPKRSLLSPKGKVSVAHL 268
            A+A EY +RR++L+KRLDVT+QSF WSD+AK   DK+ +VYQP R  L  + ++ +  +
Sbjct: 532 AAMAQEYRIRREMLLKRLDVTIQSFMWSDKAKRXQDKINQVYQPIRKELLVQTRIGIPEI 711

Query: 269 LAARQDLSKILRTSSGSIREKTACAINKVLMGRVPD 304
           LAAR+DL++I +TS+G  R++  C INKV++GRV D
Sbjct: 712 LAAREDLTRIQKTSTGESRKE--CKINKVMIGRVSD 813
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|28916693|ref|NP_666232.2| gelsolin [Mus musculus]
         (780 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

07901                                                                 152   3e-37
09469                                                                 143   3e-34
20421                                                                 121   1e-27
31845                                                                 113   2e-25
27907                                                                  93   4e-19
08500                                                                  47   3e-05
10332                                                                  45   1e-04
11981                                                                  39   0.007
38224                                                                  32   0.88 
17249                                                                  31   1.7  
18410                                                                  30   4.5  
22893                                                                  29   7.4  
>07901
          Length = 1199

 Score =  152 bits (385), Expect = 3e-37,   Method: Compositional matrix adjust.
 Identities = 101/306 (33%), Positives = 156/306 (50%), Gaps = 5/306 (1%)
 Frame = +2

Query: 84  YGDFFTGDAYVILKTVQ-LRNGNLQYDLHYWLGNECSQDESGAAAIFTVQLDDYLNGRAV 142
           YG+F+ GD+Y+IL T +     +L YD+H+W+G   SQDE G AA  TV+LD  L+ + V
Sbjct: 11  YGEFYNGDSYIILNTYKDEETEDLNYDVHFWIGKNSSQDEYGTAAYKTVELDTLLDDKPV 190

Query: 143 QHREVQGFESSTFSGYFKSGLKYKKGGVASGFKHVVPNEVVVQRLFQV----KGRRVVRA 198
           QHREVQG ESS F  YFK+G++  +GG  SGF+ +   E  + RL +      G  VVR 
Sbjct: 191 QHREVQGHESSLFKSYFKAGIQTMEGGANSGFRSIPVKEEYIPRLMRFAKDKSGHIVVR- 367

Query: 199 TEVPVSWDSFNNGDCFILDLGNNIYQWCGSGSNKFERLKATQVSKGIRDNERSGRAQVHV 258
            E+P +     +GD FI+D G  +YQ+ GS  +  E+ KA +    I+       ++V  
Sbjct: 368 -EIPRARQLVTSGDVFIMDAGXMLYQFNGSACSPMEKSKAMEYIGKIKSKRGDADSEVLD 544

Query: 259 SEEGGEPEAMLQVLGPKPALPEGTEDTAKEDAANRRLAKLYKVSNGAGSMSVSLVADENP 318
             +     A  ++L  +  + E    +  ED  N +  KL +V+             E  
Sbjct: 545 EADTSPNHAFFKMLDEE--VDEDGNASDDEDCDNDK--KLCRVNTDTRDYE---DVKEGD 703

Query: 319 FAQGALRSEDCFILDHGRDGKIFVWKGKQANMEERKAALKTASDFISKMQYPRQTQVSVL 378
                 +S+D FI D G    +FVW G  A+  E+K  L  A  ++ +   P ++ + V+
Sbjct: 704 VTLDDFKSDDVFIYDSG--DTVFVWVGSNASSAEKKNGLPLAHTYLCESGQPWRS-ICVM 874

Query: 379 PEGGET 384
            EG ++
Sbjct: 875 KEGSKS 892

 Score =  101 bits (251), Expect = 1e-21,   Method: Compositional matrix adjust.
 Identities = 84/286 (29%), Positives = 124/286 (43%), Gaps = 19/286 (6%)
 Frame = +2

Query: 463 YGQFYGGDSYIILYNYRHGGRQ--GQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPV 520
           YG+FY GDSYIIL  Y+    +     ++ W G  S+QDE   +A  T +LD  L   PV
Sbjct: 11  YGEFYNGDSYIILNTYKDEETEDLNYDVHFWIGKNSSQDEYGTAAYKTVELDTLLDDKPV 190

Query: 521 QSRVVQGKEPAHLMSLFGGKPMIIYKGGTSRDGGQTAPASI----RLFQVRASSSGATRA 576
           Q R VQG E +   S F      +  G  S  G ++ P       RL +     SG    
Sbjct: 191 QHREVQGHESSLFKSYFKAGIQTMEGGANS--GFRSIPVKEEYIPRLMRFAKDKSGHIVV 364

Query: 577 VEVMPKSGALNSNDAFVLKTPSAAYLWVGAGASEAEKTGAQELLKVLRSQ------HVQV 630
            E+      + S D F++      Y + G+  S  EK+ A E +  ++S+       V  
Sbjct: 365 REIPRARQLVTSGDVFIMDAGXMLYQFNGSACSPMEKSKAMEYIGKIKSKRGDADSEVLD 544

Query: 631 EEGSEPD-AFWEALGGK-----TAYRTSPRLKDKKMDAHPPRLFACSNRIGRFVIEEVP- 683
           E  + P+ AF++ L  +      A        DKK+         C         E+V  
Sbjct: 545 EADTSPNHAFFKMLDEEVDEDGNASDDEDCDNDKKL---------CRVNTDTRDYEDVKE 697

Query: 684 GELMQEDLATDDVMLLDTWDQVFVWVGKDSQEEEKTEALTSAKRYI 729
           G++  +D  +DDV + D+ D VFVWVG ++   EK   L  A  Y+
Sbjct: 698 GDVTLDDFKSDDVFIYDSGDTVFVWVGSNASSAEKKNGLPLAHTYL 835
>09469
          Length = 657

 Score =  143 bits (360), Expect = 3e-34,   Method: Compositional matrix adjust.
 Identities = 81/185 (43%), Positives = 113/185 (61%), Gaps = 6/185 (3%)
 Frame = +1

Query: 60  AGKEPGLQIWRVEKFDLVPVPPNLYGDFFTGDAYVILKTV-QLRNGNLQYDLHYWLGNEC 118
           AGK+PG+QIWR+  F +   P + YG FF GD+Y+IL T  +  +  L YD+H+W+G   
Sbjct: 97  AGKKPGIQIWRINSFKVETWPTDDYGTFFKGDSYIILNTYKEAESDKLLYDVHFWIGEFS 276

Query: 119 SQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESSTFSGYFKSGLKYKKGGVASGFKHVV 178
           +QDE G AA  TV+LD  L+   VQHREVQ  ES  F  YFK  + Y+ GG  SGF+HV 
Sbjct: 277 TQDEYGTAAYKTVELDTLLDDIPVQHREVQDNESELFRSYFKE-IIYEAGGADSGFRHVT 453

Query: 179 PNEVVVQRLFQV----KGR-RVVRATEVPVSWDSFNNGDCFILDLGNNIYQWCGSGSNKF 233
            ++    RLF+V    KG+ + + ATEV ++ D   + D +ILD G   YQ+ G  ++K 
Sbjct: 454 EDK-YKPRLFKVSTKTKGKSKNLVATEVKLNRDQITSDDAYILDDGACFYQFNGKTASKQ 630

Query: 234 ERLKA 238
           E  K+
Sbjct: 631 ETFKS 645

 Score = 86.3 bits (212), Expect = 4e-17,   Method: Compositional matrix adjust.
 Identities = 64/177 (36%), Positives = 86/177 (48%), Gaps = 10/177 (5%)
 Frame = +1

Query: 446 QIWRIEGSNKVPVDPAT-YGQFYGGDSYIILYNYRHGGRQGQIIYN---WQGAQSTQDEV 501
           QIWRI  S KV   P   YG F+ GDSYIIL  Y+      +++Y+   W G  STQDE 
Sbjct: 118 QIWRI-NSFKVETWPTDDYGTFFKGDSYIILNTYKEA-ESDKLLYDVHFWIGEFSTQDEY 291

Query: 502 AASAILTAQLDEELGGTPVQSRVVQGKEPAHLMSLFGGKPMIIYKGGTSRDGGQTAPASI 561
             +A  T +LD  L   PVQ R VQ  E     S F     IIY+ G +  G +      
Sbjct: 292 GTAAYKTVELDTLLDDIPVQHREVQDNESELFRSYF---KEIIYEAGGADSGFRHVTEDK 462

Query: 562 ---RLFQVRASSSGATR---AVEVMPKSGALNSNDAFVLKTPSAAYLWVGAGASEAE 612
              RLF+V   + G ++   A EV      + S+DA++L   +  Y + G  AS+ E
Sbjct: 463 YKPRLFKVSTKTKGKSKNLVATEVKLNRDQITSDDAYILDDGACFYQFNGKTASKQE 633

 Score = 32.3 bits (72), Expect = 0.71,   Method: Compositional matrix adjust.
 Identities = 25/87 (28%), Positives = 38/87 (43%)
 Frame = +1

Query: 266 EAMLQVLGPKPALPEGTEDTAKEDAANRRLAKLYKVSNGAGSMSVSLVADENPFAQGALR 325
           E + +  G        TED  K         +L+KVS      S +LVA E    +  + 
Sbjct: 403 EIIYEAGGADSGFRHVTEDKYK--------PRLFKVSTKTKGKSKNLVATEVKLNRDQIT 558

Query: 326 SEDCFILDHGRDGKIFVWKGKQANMEE 352
           S+D +ILD G     + + GK A+ +E
Sbjct: 559 SDDAYILDDG--ACFYQFNGKTASKQE 633
>20421
          Length = 455

 Score =  121 bits (303), Expect = 1e-27,   Method: Compositional matrix adjust.
 Identities = 55/110 (50%), Positives = 79/110 (71%)
 Frame = +3

Query: 421 DAATLHTSTAMAAQHGMDDDGTGQKQIWRIEGSNKVPVDPATYGQFYGGDSYIILYNYRH 480
           DA TLH+++A+AA+  M DDG+G  ++WR++  +  P+D + YG+FYGGD Y+I Y Y+ 
Sbjct: 3   DANTLHSNSALAAETQMVDDGSGTVEVWRVDNFDLKPLDKSRYGEFYGGDCYVIQYTYKV 182

Query: 481 GGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQGKEP 530
            GR   IIY W G++ST DE   +A+   +LD++LGG+PVQ RVVQ KEP
Sbjct: 183 HGRDHVIIYFWLGSKSTADEKGTAALKAVELDDKLGGSPVQVRVVQYKEP 332

 Score = 75.1 bits (183), Expect = 1e-13,   Method: Compositional matrix adjust.
 Identities = 38/89 (42%), Positives = 57/89 (64%)
 Frame = +3

Query: 66  LQIWRVEKFDLVPVPPNLYGDFFTGDAYVILKTVQLRNGNLQYDLHYWLGNECSQDESGA 125
           +++WRV+ FDL P+  + YG+F+ GD YVI  T ++ +G     +++WLG++ + DE G 
Sbjct: 75  VEVWRVDNFDLKPLDKSRYGEFYGGDCYVIQYTYKV-HGRDHVIIYFWLGSKSTADEKGT 251

Query: 126 AAIFTVQLDDYLNGRAVQHREVQGFESST 154
           AA+  V+LDD L G  VQ R VQ  E  T
Sbjct: 252 AALKAVELDDKLGGSPVQVRVVQYKEPPT 338
>31845
          Length = 409

 Score =  113 bits (283), Expect = 2e-25,   Method: Compositional matrix adjust.
 Identities = 56/110 (50%), Positives = 74/110 (67%), Gaps = 1/110 (0%)
 Frame = -1

Query: 60  AGKEPGLQIWRVEKFDLVPVPPNLYGDFFTGDAYVILKTVQLRNGN-LQYDLHYWLGNEC 118
           AGK  GLQIWR+ KF +   P   YG F++GD+Y+IL T +   G+ L +D+H+W+G E 
Sbjct: 373 AGKRVGLQIWRIVKFQVKAWPKEDYGKFYSGDSYIILNTYKEEGGDELLFDVHFWIGKES 194

Query: 119 SQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESSTFSGYFKSGLKYKKG 168
           +QDE G AA  TV+LD +L+   +QHREVQG ES  F  YFK+ L Y KG
Sbjct: 193 TQDEYGTAAYKTVELDTFLDDLPIQHREVQGHESDMFKSYFKA-LTYMKG 47

 Score = 67.4 bits (163), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 42/104 (40%), Positives = 52/104 (50%), Gaps = 2/104 (1%)
 Frame = -1

Query: 446 QIWRIEGSNKVPVDPATYGQFYGGDSYIILYNYRHGGRQGQI--IYNWQGAQSTQDEVAA 503
           QIWRI            YG+FY GDSYIIL  Y+  G    +  ++ W G +STQDE   
Sbjct: 352 QIWRIVKFQVKAWPKEDYGKFYSGDSYIILNTYKEEGGDELLFDVHFWIGKESTQDEYGT 173

Query: 504 SAILTAQLDEELGGTPVQSRVVQGKEPAHLMSLFGGKPMIIYKG 547
           +A  T +LD  L   P+Q R VQG E     S F  K +   KG
Sbjct: 172 AAYKTVELDTFLDDLPIQHREVQGHESDMFKSYF--KALTYMKG 47
>27907
          Length = 426

 Score = 92.8 bits (229), Expect = 4e-19,   Method: Compositional matrix adjust.
 Identities = 45/97 (46%), Positives = 63/97 (64%)
 Frame = +2

Query: 671 SNRIGRFVIEEVPGELMQEDLATDDVMLLDTWDQVFVWVGKDSQEEEKTEALTSAKRYIE 730
           SN  G    EE+  + +Q+DL  +DVMLLD W+ +++WVG+ S + E+  A   A  Y++
Sbjct: 8   SNASGNVKAEEIL-DFVQDDLIPEDVMLLDCWECLYLWVGQGSNKAERQGAQNLALDYLK 184

Query: 731 TDPANRDRRTPITVVRQGFEPPSFVGWFLGWDDNYWS 767
           TDPA RD  TPI  + QG+EPPSF G+F  WD + WS
Sbjct: 185 TDPAGRDPDTPIMKISQGYEPPSFTGFFGTWDRDLWS 295

 Score = 38.9 bits (89), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 25/83 (30%), Positives = 43/83 (51%), Gaps = 11/83 (13%)
 Frame = +2

Query: 568 ASSSGATRAVEVMP-KSGALNSNDAFVLKTPSAAYLWVGAGASEAEKTGAQEL-LKVLRS 625
           +++SG  +A E++      L   D  +L      YLWVG G+++AE+ GAQ L L  L++
Sbjct: 8   SNASGNVKAEEILDFVQDDLIPEDVMLLDCWECLYLWVGQGSNKAERQGAQNLALDYLKT 187

Query: 626 QH---------VQVEEGSEPDAF 639
                      +++ +G EP +F
Sbjct: 188 DPAGRDPDTPIMKISQGYEPPSF 256

 Score = 30.8 bits (68), Expect = 2.3,   Method: Compositional matrix adjust.
 Identities = 19/65 (29%), Positives = 28/65 (43%), Gaps = 3/65 (4%)
 Frame = +2

Query: 212 DCFILDLGNNIYQWCGSGSNKFERLKATQVSKGIRDNERSGR---AQVHVSEEGGEPEAM 268
           D  +LD    +Y W G GSNK ER  A  ++      + +GR     +    +G EP + 
Sbjct: 77  DVMLLDCWECLYLWVGQGSNKAERQGAQNLALDYLKTDPAGRDPDTPIMKISQGYEPPSF 256

Query: 269 LQVLG 273
               G
Sbjct: 257 TGFFG 271
>08500
          Length = 778

 Score = 46.6 bits (109), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 28/94 (29%), Positives = 50/94 (53%)
 Frame = +2

Query: 288 EDAANRRLAKLYKVSNGAGSMSVSLVADENPFAQGALRSEDCFILDHGRDGKIFVWKGKQ 347
           ++++ RR+ +L K+S   G ++   V  E   ++    S D F+LD    G +FVW GK+
Sbjct: 218 QESSRRRMPRLIKISESGGQITCKQV-KEGDISKRDFLSNDVFLLDSPAFG-VFVWCGKK 391

Query: 348 ANMEERKAALKTASDFISKMQYPRQTQVSVLPEG 381
           A++ E+   +  A  ++S   Y  +  V+ L EG
Sbjct: 392 ASVNEKSKGMAYAHSYLSDKPYSCEP-VTCLSEG 490

 Score = 46.6 bits (109), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 27/86 (31%), Positives = 46/86 (53%), Gaps = 2/86 (2%)
 Frame = +2

Query: 665 PRLFACSNRIGRFVIEEVP-GELMQEDLATDDVMLLDTWD-QVFVWVGKDSQEEEKTEAL 722
           PRL   S   G+   ++V  G++ + D  ++DV LLD+    VFVW GK +   EK++ +
Sbjct: 242 PRLIKISESGGQITCKQVKEGDISKRDFLSNDVFLLDSPAFGVFVWCGKKASVNEKSKGM 421

Query: 723 TSAKRYIETDPANRDRRTPITVVRQG 748
             A  Y+   P + +   P+T + +G
Sbjct: 422 AYAHSYLSDKPYSCE---PVTCLSEG 490
>10332
          Length = 1146

 Score = 44.7 bits (104), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 24/71 (33%), Positives = 38/71 (53%)
 Frame = +3

Query: 684 GELMQEDLATDDVMLLDTWDQVFVWVGKDSQEEEKTEALTSAKRYIETDPANRDRRTPIT 743
           G++  +D  +DDV + D+ D VFVWVG ++   EK   L  A  Y+    A+      +T
Sbjct: 21  GDVTLDDFKSDDVFIYDSGDTVFVWVGSNASSAEKKNGLPLAHNYL---CASGSPWRSVT 191

Query: 744 VVRQGFEPPSF 754
           VV++G +   F
Sbjct: 192 VVKEGSKCNQF 224

 Score = 37.7 bits (86), Expect = 0.019,   Method: Compositional matrix adjust.
 Identities = 21/66 (31%), Positives = 34/66 (51%)
 Frame = +3

Query: 324 LRSEDCFILDHGRDGKIFVWKGKQANMEERKAALKTASDFISKMQYPRQTQVSVLPEGGE 383
            +S+D FI D G    +FVW G  A+  E+K  L  A +++     P ++ V+V+ EG +
Sbjct: 42  FKSDDVFIYDSGD--TVFVWVGSNASSAEKKNGLPLAHNYLCASGSPWRS-VTVVKEGSK 212

Query: 384 TPLFKQ 389
              F  
Sbjct: 213 CNQFNS 230

 Score = 30.4 bits (67), Expect = 2.9,   Method: Compositional matrix adjust.
 Identities = 22/66 (33%), Positives = 31/66 (46%), Gaps = 8/66 (12%)
 Frame = +3

Query: 586 LNSNDAFVLKTPSAAYLWVGAGASEAEKTGAQELLKVL--------RSQHVQVEEGSEPD 637
             S+D F+  +    ++WVG+ AS AEK     L            RS  V V+EGS+ +
Sbjct: 42  FKSDDVFIYDSGDTVFVWVGSNASSAEKKNGLPLAHNYLCASGSPWRSVTV-VKEGSKCN 218

Query: 638 AFWEAL 643
            F  AL
Sbjct: 219 QFNSAL 236
>11981
          Length = 568

 Score = 39.3 bits (90), Expect = 0.007,   Method: Composition-based stats.
 Identities = 21/67 (31%), Positives = 35/67 (52%), Gaps = 7/67 (10%)
 Frame = +1

Query: 586 LNSNDAFVLKTPSAAYLWVGAGASEAEKTGAQELLK--VLRSQHVQVE-----EGSEPDA 638
           L++ D F++ T  AAY+W+G G S  EK  A + +   ++++ H  V      EG E   
Sbjct: 34  LDTKDVFIVDTKKAAYVWIGKGTSTGEKKKAMQHVHNYLMKTDHPLVSVTCLPEGREGPT 213

Query: 639 FWEALGG 645
           F+ A+  
Sbjct: 214 FFSAIAA 234

 Score = 38.9 bits (89), Expect = 0.009,   Method: Composition-based stats.
 Identities = 23/75 (30%), Positives = 39/75 (52%), Gaps = 1/75 (1%)
 Frame = +1

Query: 681 EVPGELMQEDLATDDVMLLDTWDQVFVWVGKDSQEEEKTEALTSAKRYI-ETDPANRDRR 739
           E  G + + +L T DV ++DT    +VW+GK +   EK +A+     Y+ +TD       
Sbjct: 4   EKKGPVDKSNLDTKDVFIVDTKKAAYVWIGKGTSTGEKKKAMQHVHNYLMKTDHP----L 171

Query: 740 TPITVVRQGFEPPSF 754
             +T + +G E P+F
Sbjct: 172 VSVTCLPEGREGPTF 216
>38224
          Length = 618

 Score = 32.0 bits (71), Expect = 0.88,   Method: Composition-based stats.
 Identities = 22/81 (27%), Positives = 37/81 (45%)
 Frame = +2

Query: 52  VEHPEFLKAGKEPGLQIWRVEKFDLVPVPPNLYGDFFTGDAYVILKTVQLRNGNLQYDLH 111
           +E   F+ A K     IW      ++P+PP+L   F+ G  +V   +V  +NG      H
Sbjct: 314 LEFTIFISACKNGRQNIWFAIIITVMPLPPDL---FYWGWCHVYKASVTPQNGIRGPHFH 484

Query: 112 YWLGNECSQDESGAAAIFTVQ 132
            W  +  S  +   +A+F V+
Sbjct: 485 IWPMSHISDAKRNLSAVFFVR 547
>17249
          Length = 909

 Score = 31.2 bits (69), Expect = 1.7,   Method: Composition-based stats.
 Identities = 17/43 (39%), Positives = 23/43 (53%)
 Frame = +3

Query: 422 AATLHTSTAMAAQHGMDDDGTGQKQIWRIEGSNKVPVDPATYG 464
           A T+ T TA+ A+H       GQK  W I+G+    VD A +G
Sbjct: 54  ANTIRTLTALRAKHAQ-----GQKNTWGIDGNTGNIVDMAEFG 167
>18410
          Length = 844

 Score = 29.6 bits (65), Expect = 4.5,   Method: Compositional matrix adjust.
 Identities = 19/57 (33%), Positives = 28/57 (49%), Gaps = 3/57 (5%)
 Frame = +1

Query: 690 DLATDDVMLLDTWDQVFVWVGKDS---QEEEKTEALTSAKRYIETDPANRDRRTPIT 743
           DL+ +D   L    +  ++   D    QE EK ++ + AKRYI+     R R  PIT
Sbjct: 163 DLSENDPSRLSVSSKTSIFKNLDDRARQEREKEKSASGAKRYIDRKKRERCRTQPIT 333
>22893
          Length = 580

 Score = 28.9 bits (63), Expect = 7.4,   Method: Composition-based stats.
 Identities = 18/75 (24%), Positives = 34/75 (45%)
 Frame = -2

Query: 549 TSRDGGQTAPASIRLFQVRASSSGATRAVEVMPKSGALNSNDAFVLKTPSAAYLWVGAGA 608
           T + G ++ P S ++F ++  SSG +           LNSN     + P     W  A  
Sbjct: 561 TMK*GARSLPHSAKIFSLKIKSSGFSN----------LNSN*PLQCRRPGFKPXWFXAXD 412

Query: 609 SEAEKTGAQELLKVL 623
            ++ ++G +E L ++
Sbjct: 411 XDSSRSGVREKLALI 367
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31560255|ref|NP_079752.3| family with sequence
similarity 82, member B [Mus musculus]
         (305 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

01906                                                                 151   4e-37
26031                                                                  30   1.1  
11856                                                                  29   2.7  
26379                                                                  27   9.2  
>01906
          Length = 1186

 Score =  151 bits (381), Expect = 4e-37,   Method: Compositional matrix adjust.
 Identities = 67/134 (50%), Positives = 89/134 (66%)
 Frame = -1

Query: 172  YEGIKVKIANAYVIKEHFEKAIELNPKDATSIHLMGIWCYTFAEMPWYQRRIAKVLFANP 231
            YEG K +I+NAYV+KEHF KA ELNPKDAT+++ +G+WC+ FA+MPWYQR+IA  LFA+P
Sbjct: 1186 YEGTKARISNAYVVKEHFMKATELNPKDATTLYTLGVWCFLFADMPWYQRKIAGALFASP 1007

Query: 232  PSSTYEEALRYFHKAEEVDPNFYSXXXXXXXXXXXXXXXXXXAAFWLVKAKGYPAHTEED 291
            P+STY EAL +F KAEE +PNF+S                  A   L +A+ +P  T +D
Sbjct: 1006 PTSTYAEALEFFQKAEETEPNFFSKNTMMLGKTYLRLGDKKLAMLHLTRARDFPLVTPDD 827

Query: 292  KQIQTEAAQLLTGL 305
             +   EA  LLT +
Sbjct: 826  TEAHKEATDLLTKM 785
>26031
          Length = 442

 Score = 30.0 bits (66), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 13/30 (43%), Positives = 17/30 (56%), Gaps = 4/30 (13%)
 Frame = -2

Query: 16  VCQQTRTWGSRG----RCGAWGVRACEVIG 41
           +C ++ TW  RG     CGAW   AC+ IG
Sbjct: 117 ICDRSVTWNDRGVACESCGAWFHAACQYIG 28
>11856
          Length = 1298

 Score = 28.9 bits (63), Expect = 2.7,   Method: Compositional matrix adjust.
 Identities = 16/42 (38%), Positives = 25/42 (59%), Gaps = 5/42 (11%)
 Frame = -2

Query: 80  EILAQADYL-----YESGETEKLYQLLIQYKESEDGELLWRL 116
           ++LAQ + L     +   + EK+Y   +Q +  E+GELLWRL
Sbjct: 538 QVLAQNNLLTFFTAFSRDQEEKIY---VQDRIKENGELLWRL 422
>26379
          Length = 1488

 Score = 26.9 bits (58), Expect = 9.2,   Method: Compositional matrix adjust.
 Identities = 20/60 (33%), Positives = 23/60 (38%)
 Frame = +2

Query: 27  GRCGAWGVRACEVIGNTRPFKRGFLFSALSYLGFETYQIISQAAVVHATAKVEEILAQAD 86
           GRC    V AC     TR  + GF  + L  LGF  +        VH T   E  L   D
Sbjct: 599 GRCSXRIVVACLPPRETREARTGFKETQLPTLGFVWFV*TVSQGPVHKTQSSEAHLENKD 778
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6755939|ref|NP_035806.1| UNC-119 homolog [Mus
musculus]
         (240 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

19759                                                                 137   4e-37
07191                                                                  27   7.7  
>19759
          Length = 439

 Score =  137 bits (345), Expect(2) = 4e-37,   Method: Compositional matrix adjust.
 Identities = 63/93 (67%), Positives = 76/93 (81%)
 Frame = +3

Query: 128 FVRYQFTPAFLRLRQVGATVEFTVGDKPVNNFRMIERHYFRNQLLKSFDFHFGFCIPSSK 187
           FVRYQFTP FL+L+ VGATVEF VGDK V+ FRM+E+HYF ++LLK FDF FGFCIP S+
Sbjct: 3   FVRYQFTPQFLKLKTVGATVEFVVGDKEVSKFRMVEKHYFHDRLLKCFDFEFGFCIPHSR 182

Query: 188 NTCEHIYDFPPLSEELISEMIRHPYETQSDSFY 220
           NT EHIY+FP L+ + + EMI  PYET+SDS Y
Sbjct: 183 NTVEHIYEFPELTPDQMREMIDRPYETRSDSLY 281

 Score = 34.3 bits (77), Expect(2) = 4e-37,   Method: Compositional matrix adjust.
 Identities = 12/18 (66%), Positives = 17/18 (94%)
 Frame = +2

Query: 221 FVDDRLVMHNKADYSYSG 238
            V+D+L+MHNKADY+Y+G
Sbjct: 281 LVEDKLIMHNKADYAYNG 334
>07191
          Length = 2615

 Score = 26.9 bits (58), Expect = 7.7,   Method: Compositional matrix adjust.
 Identities = 16/53 (30%), Positives = 21/53 (39%)
 Frame = -3

Query: 178  HFGFCIPSSKNTCEHIYDFPPLSEELISEMIRHPYETQSDSFYFVDDRLVMHN 230
            HFG C      TC + Y    L      +   H Y+ Q+D  Y  +  LV H 
Sbjct: 1911 HFGHCYLPVSRTCHYHYRSQGLHHLPFVKRCHH-YQVQADYLYHTEKSLVHHQ 1756
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|8567340|ref|NP_059506.1| coatomer protein complex,
subunit gamma 2 [Mus musculus]
         (871 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

39334                                                                 108   4e-37
34356                                                                  32   1.3  
02513                                                                  30   5.9  
>39334
          Length = 432

 Score =  108 bits (270), Expect(3) = 4e-37,   Method: Composition-based stats.
 Identities = 51/80 (63%), Positives = 67/80 (83%), Gaps = 1/80 (1%)
 Frame = +1

Query: 793 TLEEAVNNIITFLGMQPCERSDKVPENKNSHSLYLAGVYRGGYDLLVRSRLAL-ADGVTM 851
           TLEEA+ NII +LG+QPCERSDKVPE K+SH+LYLAG+YRGG+D LVRS+LAL + GVTM
Sbjct: 151 TLEEAIKNIIQYLGLQPCERSDKVPEGKSSHTLYLAGMYRGGHDALVRSKLALDSSGVTM 330

Query: 852 QVTVRSKERTPVDVILASVG 871
           Q+TVRS + +  +V+  ++ 
Sbjct: 331 QLTVRSTDPSVSEVLATAIA 390

 Score = 52.4 bits (124), Expect(3) = 4e-37,   Method: Compositional matrix adjust.
 Identities = 21/26 (80%), Positives = 26/26 (100%)
 Frame = +2

Query: 744 YDDEYVLEDLEVTVSDHIQKILKPNF 769
           YDDEYVLED+EVTV+DH+QK++KPNF
Sbjct: 2   YDDEYVLEDVEVTVADHVQKVMKPNF 79

 Score = 33.5 bits (75), Expect(3) = 4e-37,   Method: Composition-based stats.
 Identities = 14/24 (58%), Positives = 18/24 (75%)
 Frame = +3

Query: 767 PNFAAAWEEVGDAFEKEETFALSS 790
           P FAA+WEEVG   E E+T+ LS+
Sbjct: 72  PTFAASWEEVGTENELEDTYVLST 143
>34356
          Length = 1126

 Score = 31.6 bits (70), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 22/74 (29%), Positives = 33/74 (44%)
 Frame = -3

Query: 412 EYKKAIVDCIISIVEENPESKEAGLAHLCEFIEDCEHTVLATKILHLLGKEGPRTPVPSK 471
           +  K + DC    V+ N  SK   L+  CE+I++   +    K L    KE  R  V S+
Sbjct: 500 QLSKLVPDCAQETVKPNQASKGGILSKACEYIQELRSS---NKTLLETVKEAERVTVDSE 330

Query: 472 YIRFIFNRVVLENE 485
            +R     V  +NE
Sbjct: 329 LVRNQLEEVKKQNE 288
>02513
          Length = 1543

 Score = 29.6 bits (65), Expect = 5.9,   Method: Composition-based stats.
 Identities = 14/34 (41%), Positives = 18/34 (52%)
 Frame = -2

Query: 634 VQLTEAETEYFVRCVKHMFTDHIVFQFDCTNTLN 667
           VQLT+ E    + C KH FT   V+   C + LN
Sbjct: 165 VQLTDTERNIHIACHKHTFTLSHVYIMACVDLLN 64
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|33239415|ref|NP_778169.1| Bcl-2 inhibitor of
transcription isoform a [Mus musculus]
         (182 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

04449                                                                 149   6e-37
09510                                                                 144   2e-35
00889                                                                  32   0.20 
13670                                                                  31   0.28 
32663                                                                  29   1.2  
01984                                                                  29   1.4  
39159                                                                  28   2.3  
>04449
          Length = 891

 Score =  149 bits (376), Expect = 6e-37,   Method: Compositional matrix adjust.
 Identities = 77/139 (55%), Positives = 95/139 (68%)
 Frame = +3

Query: 43  QNSTSEANRDTETGTEASILGESGEYKMILVVRTDLKMGKGKVAAQCSHAAVSAYKQTQR 102
           Q     A+R  E  T A  + + GE KM+LVV  +LKMGKGK+AAQCSHAAV A ++   
Sbjct: 327 QRCEERADRRLEHDTIAP-MADGGEVKMVLVVNNELKMGKGKIAAQCSHAAVGAVERCFH 503

Query: 103 RSPQVLKEWEYCGQPKVVVKAPDEDTLIQLLTHAKTLGLTVSLIQDAGRTQIEPGSRTVL 162
           ++P+  K+W   GQPKVVVKA     L QL + A+  GL   LI DAGRTQI PGS+TVL
Sbjct: 504 QNPEAFKKWRLHGQPKVVVKADSTAMLKQLGSKAQAAGLVTCLISDAGRTQIAPGSKTVL 683

Query: 163 GIGPGPVELIDEVTGHLKL 181
           G+GPGP  L+D+VTGHLKL
Sbjct: 684 GVGPGPASLVDQVTGHLKL 740
>09510
          Length = 462

 Score =  144 bits (364), Expect = 2e-35,   Method: Compositional matrix adjust.
 Identities = 70/115 (60%), Positives = 85/115 (73%)
 Frame = +3

Query: 67  EYKMILVVRTDLKMGKGKVAAQCSHAAVSAYKQTQRRSPQVLKEWEYCGQPKVVVKAPDE 126
           E KM+LVV  +LKMGKGK+AAQCSHAAV A ++   ++P+  K+W   GQPKVVVKA   
Sbjct: 3   EVKMVLVVNNELKMGKGKIAAQCSHAAVGAVERCFHQNPEAFKKWRLHGQPKVVVKADST 182

Query: 127 DTLIQLLTHAKTLGLTVSLIQDAGRTQIEPGSRTVLGIGPGPVELIDEVTGHLKL 181
             L QL + A+  GL   LI DAGRTQI PGS+TVLG+GPGP  L+D+VTGHLKL
Sbjct: 183 AMLKQLGSKAQAAGLVTCLISDAGRTQIAPGSKTVLGVGPGPASLVDQVTGHLKL 347
>00889
          Length = 1710

 Score = 31.6 bits (70), Expect = 0.20,   Method: Compositional matrix adjust.
 Identities = 19/49 (38%), Positives = 23/49 (46%), Gaps = 6/49 (12%)
 Frame = +1

Query: 111  WEYCGQPKVVVKAPDEDTL------IQLLTHAKTLGLTVSLIQDAGRTQ 153
            WEYC    V   A +EDT+      IQL+ H KT+  T     D  R Q
Sbjct: 1054 WEYCYTCSVSTAALNEDTVATLNKAIQLM-HTKTMQFTKCTYNDKVRRQ 1197
>13670
          Length = 910

 Score = 30.8 bits (68), Expect = 0.28,   Method: Compositional matrix adjust.
 Identities = 12/16 (75%), Positives = 14/16 (87%)
 Frame = -2

Query: 166 PGPVELIDEVTGHLKL 181
           PGP  L+D+VTGHLKL
Sbjct: 909 PGPASLVDQVTGHLKL 862
>32663
          Length = 1110

 Score = 28.9 bits (63), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 20/72 (27%), Positives = 37/72 (51%), Gaps = 7/72 (9%)
 Frame = -1

Query: 10   EYLVHPGTLSLAAGVACGMCLGWGLRSHLGMFPQNST--SEANRDTET----GTEASIL- 62
             Y++H   +     ++  MCL +G    LG+FP  ST  +E    TE+    G+ A++  
Sbjct: 1002 SYIIHQRLIEFFKSMSAQMCLDFG----LGLFPLVSTGVAEVILFTESVAFLGSSAAVFV 835

Query: 63   GESGEYKMILVV 74
            G+ G + ++ V+
Sbjct: 834  GDGGRFVLLYVM 799
>01984
          Length = 534

 Score = 28.9 bits (63), Expect = 1.4,   Method: Compositional matrix adjust.
 Identities = 15/37 (40%), Positives = 18/37 (48%), Gaps = 5/37 (13%)
 Frame = +2

Query: 111 WEYCGQPKVVVKAPDEDTLIQL-----LTHAKTLGLT 142
           WEYC    V   A +EDT+  L     L H KT+  T
Sbjct: 311 WEYCYTCSVSTAALNEDTVATLNKAIQLMHTKTMQFT 421
>39159
          Length = 567

 Score = 28.1 bits (61), Expect = 2.3,   Method: Compositional matrix adjust.
 Identities = 10/23 (43%), Positives = 14/23 (60%)
 Frame = +3

Query: 91  HAAVSAYKQTQRRSPQVLKEWEY 113
           HA+V  +  T R   +V KEW+Y
Sbjct: 372 HASVRCFSFTNRMEREVTKEWQY 440
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31543349|ref|NP_032766.2| N-ethylmaleimide sensitive
fusion protein [Mus musculus]
         (744 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

32579                                                                 144   1e-36
03022                                                                 145   7e-35
07243                                                                 143   2e-34
01642                                                                 132   6e-31
23766                                                                 127   2e-29
19129                                                                 126   3e-29
02582                                                                 117   1e-26
07247                                                                 117   2e-26
38672                                                                  89   1e-22
12235                                                                  85   1e-16
00810                                                                  80   3e-15
20270                                                                  77   2e-14
02194                                                                  57   2e-08
17843                                                                  55   9e-08
26408                                                                  48   2e-05
25671                                                                  47   2e-05
14413                                                                  47   3e-05
01279                                                                  34   0.27 
19561                                                                  30   3.2  
27434                                                                  29   5.9  
>32579
          Length = 752

 Score =  144 bits (364), Expect(2) = 1e-36,   Method: Compositional matrix adjust.
 Identities = 61/111 (54%), Positives = 86/111 (77%)
 Frame = -2

Query: 562 FPFIKICSPDKMIGFSETAKCQAMKKIFDDAYKSQLSCVVVDDIERLLDYVPIGPRFSNX 621
            PF+K+CSP+ M+G++E AKC  ++KIFDDAY+S LSC+VVD++ERLLDY PIGPR+SN 
Sbjct: 748 LPFVKVCSPEDMVGYTELAKCLQIRKIFDDAYRSTLSCIVVDNVERLLDYGPIGPRYSNL 569

Query: 622 XXXXXXXXXXXXXXXGRKLLIIGTTSRKDVLQEMEMLNAFSTTIHVPNIAT 672
                          GRKLLI+ T+SR++VL+EMEML+AF++ +HVPN+++
Sbjct: 568 TLQALLVLLKKQPPKGRKLLILCTSSRREVLEEMEMLSAFTSVLHVPNLSS 416

 Score = 27.7 bits (60), Expect(2) = 1e-36,   Method: Compositional matrix adjust.
 Identities = 13/26 (50%), Positives = 17/26 (65%)
 Frame = -3

Query: 713 LIEMSLQMDPEYRVRKFLALMREEGA 738
           LI+M+ Q +P  R  KFL+ M EEG 
Sbjct: 297 LIDMARQTEPSQRAIKFLSKMEEEGG 220
>03022
          Length = 2255

 Score =  145 bits (365), Expect = 7e-35,   Method: Compositional matrix adjust.
 Identities = 97/258 (37%), Positives = 138/258 (53%), Gaps = 4/258 (1%)
 Frame = +2

Query: 238  RVFPPEIVEQMGCKHVKGILLYGPPGCGKTLLARQIGKMLNAREPKV----VNGPEILNK 293
            R+  PE+    G     GI+L GPPGCGKTL+A+ +     A E  +    + GPE+L+K
Sbjct: 1484 RIHDPEVSSAFGLPTNSGIILVGPPGCGKTLVAKAM-----ANEAGLNFIYIKGPELLDK 1648

Query: 294  YVGESEANIRKLFADAEEEQRRLGANSGLHIIIFDEIDAICKQRGSMAGSTGVHDTVVNQ 353
            YVGESE N+R+ F  A+             +I FDE+D +C  R +  GS  V  +V NQ
Sbjct: 1649 YVGESERNLREKFDKAQA--------CAPCLIFFDEMDTLCSNRQNNDGSN-VGKSVTNQ 1801

Query: 354  LLSKIDGVEQLNNILVIGMTNRPDLIDEALLRPGRLEVKMEIGLPDEKGRLQILHIHTAR 413
            LL+ +DG  + + + V+G TN  + +D AL RPGR + K+ IGLPD  GRL IL   T  
Sbjct: 1802 LLALMDGCGERSQVYVMGATNIIENVDPALQRPGRFDRKIFIGLPDTDGRLDILRALTK- 1978

Query: 414  MRGHQLLSADVDIKELAVETKNFSGAELEGLVRAAQSTAMNRHIKASTKVEVDMEKAESL 473
              G Q      D+++LA +T+ FSGA+L+ LV  A + A+    K S   +   E +   
Sbjct: 1979 -GGSQRKLESCDMQQLAQDTEGFSGADLKHLVNEASTIAL----KESMADQAWREDSHRE 2143

Query: 474  QVTRGDFLASLENDIKPA 491
             V  GD        +KP+
Sbjct: 2144 YVVTGDQFTRALQLVKPS 2197

 Score = 66.2 bits (160), Expect = 4e-11,   Method: Compositional matrix adjust.
 Identities = 84/316 (26%), Positives = 136/316 (43%), Gaps = 44/316 (13%)
 Frame = +2

Query: 337  RGSMAGSTGVHDTVVNQLLSKIDGV-EQLNNILVIGMTNRPDLIDEALLRPGRLEVKMEI 395
            R    GS  +   +V++L S ID + E+  N++V+  T+R + +   L  PGR  ++  +
Sbjct: 863  RTPPGGSKDMMTRIVSELGSCIDELQEKPENVVVVATTSRIEAVHRDLRIPGRF-MEKAL 1039

Query: 396  GLPDEKGRLQILHIHTARMRGHQLLSADVDIKELAVETKNFSGAELEGLVRAAQSTAMNR 455
            G+PDE  R  +L     R+     LS  + +K LA  T  F   +L  LV  A STA  R
Sbjct: 1040 GMPDEGSREGLLQ----RLCSRYTLSPHLKLKTLARLTPGFVAGDLRALVHGAFSTAFRR 1207

Query: 456  --------HIKASTK----------------VEVDMEKAESLQVTRGDFLASLENDIKPA 491
                      ++ST+                +    +   ++ +T  DF+ +L+   +PA
Sbjct: 1208 VRNLYRTESAESSTRRHPFPPLPPAHLTGKDIXPQEQDIAAVALTEEDFMGALKK-AQPA 1384

Query: 492  FGTNQEDYASYIMNGIIKWGDPVTRVLDDGEL--LVQQTKNSD----RTPLVS------- 538
                +E +A+           P T   D G L  +  Q K+S       P VS       
Sbjct: 1385 --AKREGFATV----------PTTTWEDVGALSNVRAQLKDSILCRIHDPEVSSAFGLPT 1528

Query: 539  ---VLLEGPPHSGKTALAAKIAEESNFPFIKICSP---DKMIGFSETAKCQAMKKIFDDA 592
               ++L GPP  GKT +A  +A E+   FI I  P   DK +G SE    + +++ FD A
Sbjct: 1529 NSGIILVGPPGCGKTLVAKAMANEAGLNFIYIKGPELLDKYVGESE----RNLREKFDKA 1696

Query: 593  YKSQLSCVVVDDIERL 608
                   +  D+++ L
Sbjct: 1697 QACAPCLIFFDEMDTL 1744
>07243
          Length = 1112

 Score =  143 bits (361), Expect = 2e-34,   Method: Compositional matrix adjust.
 Identities = 97/264 (36%), Positives = 146/264 (55%), Gaps = 10/264 (3%)
 Frame = +1

Query: 219 GIGGLDKEFSDIFRRAFASRVFPPEIVEQMGCKHVKGILLYGPPGCGKTLLARQIGKMLN 278
            IGGL ++  ++ R      +  PE+  ++G    KG LLYGPPG GKTLLAR +   L+
Sbjct: 208 AIGGLTEQIREL-REVIELPLLNPELFLRVGITPPKGCLLYGPPGTGKTLLARAVASQLD 384

Query: 279 AREPKVVNGPEILNKYVGESEANIRKLFADAEEEQRRLGANSGLHIIIFDEIDAICKQRG 338
           A   KVV+   I++KY+GES   IR++F  A + Q          II  DEIDAI  +R 
Sbjct: 385 ANFLKVVSS-AIVDKYIGESARLIREMFNYARDHQP--------CIIFMDEIDAIGGRRF 537

Query: 339 SMAGSTG--VHDTVVNQLLSKIDGVEQLNNILVIGMTNRPDLIDEALLRPGRLEVKMEIG 396
           S   S    +  T++ +LL+++DG + L  + +I  TNRPD +D ALLRPGRL+ K+EI 
Sbjct: 538 SEGTSADREIQRTLM-ELLNQMDGFDSLGQVKMIMATNRPDTLDPALLRPGRLDRKIEIP 714

Query: 397 LPDEKGRLQILHIHTARMRGHQLLSADVDIKELAVETKNFSGAELEGL--------VRAA 448
           LP+E+ RL+IL IH   +  H     ++D + +   + NF+GA+L  +        +RA 
Sbjct: 715 LPNEQARLEILKIHALIIAKH----GEIDYEAIVKLSDNFNGADLRNVCTEAGLFAIRAE 882

Query: 449 QSTAMNRHIKASTKVEVDMEKAES 472
           +   +      + +   D +K ES
Sbjct: 883 REYVIQEDFMKAVRKVSDNKKLES 954

 Score = 41.6 bits (96), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 27/76 (35%), Positives = 44/76 (57%), Gaps = 3/76 (3%)
 Frame = +1

Query: 534 TPLVSVLLEGPPHSGKTALAAKIAEESNFPFIKICSP---DKMIGFSETAKCQAMKKIFD 590
           TP    LL GPP +GKT LA  +A + +  F+K+ S    DK IG  E+A+   ++++F+
Sbjct: 301 TPPKGCLLYGPPGTGKTLLARAVASQLDANFLKVVSSAIVDKYIG--ESARL--IREMFN 468

Query: 591 DAYKSQLSCVVVDDIE 606
            A   Q   + +D+I+
Sbjct: 469 YARDHQPCIIFMDEID 516
>01642
          Length = 1406

 Score =  132 bits (331), Expect = 6e-31,   Method: Compositional matrix adjust.
 Identities = 84/241 (34%), Positives = 133/241 (55%), Gaps = 3/241 (1%)
 Frame = -1

Query: 220 IGGLDKEFSDIFRRAFASRVFPPEIVEQMGCKHVKGILLYGPPGCGKTLLARQIGKMLNA 279
           IGG+D +  ++ R A    +   E+ +Q+G    +G+L+YGPPGCGKT+LA+ +     A
Sbjct: 989 IGGMDIQKQEV-REAVELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAKAVAHHTTA 813

Query: 280 REPKVVNGPEILNKYVGESEANIRKLFADAEEEQRRLGANSGLHIIIFDEIDAICKQR-G 338
              +VV G E + KY+GE    +R +F        RL   +   II  DEIDAI  +R  
Sbjct: 812 AFIRVV-GSEFVQKYLGEGPRMVRDVF--------RLAKENAPAIIFIDEIDAIATKRFD 660

Query: 339 SMAGSTGVHDTVVNQLLSKIDGVEQLNNILVIGMTNRPDLIDEALLRPGRLEVKMEIGLP 398
           +  G+      ++ +LL+++DG +Q  N+ VI  TNR D +D ALLRPGRL+ K+E  LP
Sbjct: 659 AQTGADREVQRILLELLNQMDGFDQTVNVKVIMATNRADTLDPALLRPGRLDRKIEFPLP 480

Query: 399 DEKGRLQILHIHTARMRGHQLLSADVDIKELAVETKNFSGAELEGLVRAA--QSTAMNRH 456
           D + +  I    T +M     +S +VD+++        SGA++  + + A  Q+   NR+
Sbjct: 479 DRRQKRLIFSTITGKMN----ISEEVDLEDYVARPDKISGADINAICQEAGMQAVRENRY 312

Query: 457 I 457
           +
Sbjct: 311 V 309

 Score = 32.7 bits (73), Expect = 0.56,   Method: Compositional matrix adjust.
 Identities = 20/75 (26%), Positives = 38/75 (50%), Gaps = 3/75 (4%)
 Frame = -1

Query: 535 PLVSVLLEGPPHSGKTALAAKIAEESNFPFIKICSPD---KMIGFSETAKCQAMKKIFDD 591
           P   VL+ GPP  GKT LA  +A  +   FI++   +   K +G       + ++ +F  
Sbjct: 896 PPRGVLMYGPPGCGKTMLAKAVAHHTTAAFIRVVGSEFVQKYLGEGP----RMVRDVFRL 729

Query: 592 AYKSQLSCVVVDDIE 606
           A ++  + + +D+I+
Sbjct: 728 AKENAPAIIFIDEID 684
>23766
          Length = 1463

 Score =  127 bits (319), Expect = 2e-29,   Method: Compositional matrix adjust.
 Identities = 76/212 (35%), Positives = 125/212 (58%), Gaps = 2/212 (0%)
 Frame = +1

Query: 244 IVEQMGCKHVKGILLYGPPGCGKTLLARQIGKMLNAREPKVVNGPEILNKYVGESEANIR 303
           ++ + G +  KG++LYGPPG GKTLLA+ +    +A   +VV G E++ KY+G+    +R
Sbjct: 127 VLRRDGNQAPKGVILYGPPGTGKTLLAKAVANQTSATFLRVV-GSELIQKYLGDGPKLVR 303

Query: 304 KLFADAEEEQRRLGANSGLHIIIFDEIDAICKQR--GSMAGSTGVHDTVVNQLLSKIDGV 361
           +LF  AEE            I+  DEIDA+  +R   +  G   +  T++ +LL+++DG 
Sbjct: 304 ELFRVAEEH--------APSIVFIDEIDAVGTKRYESNSGGEREIQRTML-ELLNQLDGF 456

Query: 362 EQLNNILVIGMTNRPDLIDEALLRPGRLEVKMEIGLPDEKGRLQILHIHTARMRGHQLLS 421
           +   ++ VI  TNR + +D AL+RPGR++ K+E  LPDEK + +I  IHT+RM     L+
Sbjct: 457 DSRGDVKVIMATNRIETLDPALIRPGRIDRKIEFPLPDEKTKRRIFTIHTSRM----TLA 624

Query: 422 ADVDIKELAVETKNFSGAELEGLVRAAQSTAM 453
            DV+I +  +   + SGA+++ +   A   A+
Sbjct: 625 GDVNIDDYVMSKDDLSGADIKAICTEAGLLAL 720

 Score = 34.3 bits (77), Expect = 0.21,   Method: Compositional matrix adjust.
 Identities = 18/68 (26%), Positives = 39/68 (57%)
 Frame = +1

Query: 539 VLLEGPPHSGKTALAAKIAEESNFPFIKICSPDKMIGFSETAKCQAMKKIFDDAYKSQLS 598
           V+L GPP +GKT LA  +A +++  F+++   + +  +      + ++++F  A +   S
Sbjct: 163 VILYGPPGTGKTLLAKAVANQTSATFLRVVGSELIQKYLGDGP-KLVRELFRVAEEHAPS 339

Query: 599 CVVVDDIE 606
            V +D+I+
Sbjct: 340 IVFIDEID 363
>19129
          Length = 1020

 Score =  126 bits (317), Expect = 3e-29,   Method: Compositional matrix adjust.
 Identities = 80/196 (40%), Positives = 112/196 (57%), Gaps = 2/196 (1%)
 Frame = +1

Query: 211 PDWNFEKMGIGGLDKEFSDIFRRAFASRVFPPEIVEQMGCKHVKGILLYGPPGCGKTLLA 270
           PD  +E   +GGLDK+  +I +      V  PE+ E +G    KG+LLYGPPG GKTLLA
Sbjct: 472 PDSTYEM--VGGLDKQIKEI-KEVIELPVKHPELFEALGIAQPKGVLLYGPPGTGKTLLA 642

Query: 271 RQIGKMLNAREPKVVNGPEILNKYVGESEANIRKLFADAEEEQRRLGANSGLHIIIFDEI 330
           R +         +V +G E++ K++GE    +R+LF  A E            II  DEI
Sbjct: 643 RAVAHHTECTFIRV-SGSELVQKFIGEGSRMVRELFVMAREH--------APSIIFMDEI 795

Query: 331 DAICKQR--GSMAGSTGVHDTVVNQLLSKIDGVEQLNNILVIGMTNRPDLIDEALLRPGR 388
           D+I   R  G   G + V  T++ +LL+++DG E   NI VI  TNR D++D ALLRPGR
Sbjct: 796 DSIGSSRLEGGSGGDSEVQRTML-ELLNQLDGFEPKQNIKVIMATNRIDILDSALLRPGR 972

Query: 389 LEVKMEIGLPDEKGRL 404
           ++ K+E   P+E+ RL
Sbjct: 973 IDRKIEFPPPNEEARL 1020

 Score = 35.0 bits (79), Expect = 0.098,   Method: Compositional matrix adjust.
 Identities = 22/73 (30%), Positives = 39/73 (53%), Gaps = 3/73 (4%)
 Frame = +1

Query: 539 VLLEGPPHSGKTALAAKIAEESNFPFIKICSPD---KMIGFSETAKCQAMKKIFDDAYKS 595
           VLL GPP +GKT LA  +A  +   FI++   +   K IG       + ++++F  A + 
Sbjct: 598 VLLYGPPGTGKTLLARAVAHHTECTFIRVSGSELVQKFIG----EGSRMVRELFVMAREH 765

Query: 596 QLSCVVVDDIERL 608
             S + +D+I+ +
Sbjct: 766 APSIIFMDEIDSI 804
>02582
          Length = 1101

 Score =  117 bits (294), Expect = 1e-26,   Method: Compositional matrix adjust.
 Identities = 85/272 (31%), Positives = 136/272 (50%), Gaps = 32/272 (11%)
 Frame = +3

Query: 220 IGGLDKEFSDIFRRAFASRVFPPEIVEQMGCKHVKGILLYGPPGCGKTLLARQIGKMLNA 279
           IGGLD     I R+A    +  P+  + +G    KG+LLYGPPGCGKT LA+      + 
Sbjct: 147 IGGLDLVKLQI-RQAVEWPLLYPDTFQALGLPLTKGVLLYGPPGCGKTTLAQAAATACHV 323

Query: 280 REPKVVNGPEILNKYVGESEANIRKLFADAEEEQRRLGANSGLHIIIFDEIDAICKQRGS 339
               + +  ++ + YVG++E  I + F    ++ R L  +    I+  DE+DAI  +R  
Sbjct: 324 TFLSL-SCAQLYSPYVGDAEKKISETF----QKARALAPS----ILFLDEMDAIVGKRSD 476

Query: 340 MAGSTGVHDTVVNQLLSKIDGV--------------------------------EQLNNI 367
            +  +GV + V++ LL+++DG+                                    ++
Sbjct: 477 SSLGSGVSERVLSALLNEMDGIGVRLDDKSDSREMEIEGSSDHTPQVRQHAVKEAHDRHV 656

Query: 368 LVIGMTNRPDLIDEALLRPGRLEVKMEIGLPDEKGRLQILHIHTARMRGHQLLSADVDIK 427
           LV+  TNRPD++D ALLRPGR++  + +  PD +GRLQ   IHT +M     L  DVD+K
Sbjct: 657 LVVAATNRPDMLDPALLRPGRMDRLIYVPPPDVQGRLQSFTIHTRKMP----LGKDVDVK 824

Query: 428 ELAVETKNFSGAELEGLVRAAQSTAMNRHIKA 459
           +LA  T  ++GA+++ L       A+   + A
Sbjct: 825 QLADLTAGYTGADIKTLCNEVGLLALKESMSA 920
>07247
          Length = 1753

 Score =  117 bits (293), Expect = 2e-26,   Method: Compositional matrix adjust.
 Identities = 75/189 (39%), Positives = 113/189 (59%), Gaps = 2/189 (1%)
 Frame = -2

Query: 262  PGCGKTLLARQIGKMLNAREPKVVNGPEILNKYVGESEANIRKLFADAEEEQRRLGANSG 321
            PG GKTLLAR +   L+    KVV+   I++KY+GES   IR++FA A + +        
Sbjct: 1407 PGTGKTLLARAVASQLDCNFLKVVSSA-IVDKYIGESARLIREMFAFARDHEP------- 1252

Query: 322  LHIIIFDEIDAICKQRGSMAGSTG--VHDTVVNQLLSKIDGVEQLNNILVIGMTNRPDLI 379
              II  DEIDAI  +R S   S    +  T++ +LL+++DG + L  + +I  TNRPD +
Sbjct: 1251 -CIIFMDEIDAIGGRRFSEGTSADREIQRTLM-ELLNQMDGFDALGQVKMIMATNRPDTL 1078

Query: 380  DEALLRPGRLEVKMEIGLPDEKGRLQILHIHTARMRGHQLLSADVDIKELAVETKNFSGA 439
            D ALLRPGRL+ K+EI LP+E+ RL+IL IH   +  H     ++D + +   +++F+GA
Sbjct: 1077 DPALLRPGRLDRKIEISLPNEQARLEILKIHANPIAKH----GEIDWEAVVKLSEDFNGA 910

Query: 440  ELEGLVRAA 448
            +L  +   A
Sbjct: 909  DLRNVCTEA 883
>38672
          Length = 730

 Score = 88.6 bits (218), Expect(2) = 1e-22,   Method: Compositional matrix adjust.
 Identities = 54/145 (37%), Positives = 87/145 (60%), Gaps = 6/145 (4%)
 Frame = -3

Query: 346 VHDTVVNQLLSKIDGVEQLNNILVIGMTNRPDLIDEALLRPGRLEVKMEIGLPDEKGRLQ 405
           V   +V+QLL+ +DG++Q ++++V+  TNRP+ +D AL R GR + +++IG+PD  GRL+
Sbjct: 593 VERRIVSQLLTLMDGLKQRSHVIVMAATNRPNSVDAALRRFGRFDREVDIGIPDATGRLE 414

Query: 406 ILHIHTARMRGHQLLSADVDIKELAVETKNFSGAELEGLVRAAQSTAMNRHIKASTKV-- 463
           IL IHT  M+    L+ DVD++++A ET    GA++  L     S A  + I+    +  
Sbjct: 413 ILRIHTKNMK----LADDVDLEQVASETHGHVGADVAALC----SEAALQQIREKMDLID 258

Query: 464 ----EVDMEKAESLQVTRGDFLASL 484
                +D E  +SL VT  DF  +L
Sbjct: 257 LEDDTIDAEVLDSLAVTMDDFRWAL 183

 Score = 36.6 bits (83), Expect(2) = 1e-22,   Method: Compositional matrix adjust.
 Identities = 20/48 (41%), Positives = 29/48 (60%)
 Frame = -1

Query: 290 ILNKYVGESEANIRKLFADAEEEQRRLGANSGLHIIIFDEIDAICKQR 337
           I++K  GESE+N+RK F +AE+        +   II  DE+DAI  +R
Sbjct: 730 IMSKLAGESESNLRKAFEEAEK--------NAPAIIFIDELDAIAPKR 611
>12235
          Length = 1749

 Score = 85.1 bits (209), Expect = 1e-16,   Method: Compositional matrix adjust.
 Identities = 52/165 (31%), Positives = 88/165 (53%), Gaps = 1/165 (0%)
 Frame = +1

Query: 285 VNGPEILNKYVGESEANIRKLFADAEEEQRRLGANSGLHIIIFDEIDAICKQR-GSMAGS 343
           V+G E L  +VG   + +R +FA A +        +   I+  DEIDA+ ++R G   G 
Sbjct: 25  VSGSEFLEMFVGVGPSRVRDMFATARK--------NAPCILFVDEIDAVGRKRSGRNFGG 180

Query: 344 TGVHDTVVNQLLSKIDGVEQLNNILVIGMTNRPDLIDEALLRPGRLEVKMEIGLPDEKGR 403
               +  +NQLL ++DG      ++V+  TNR D++D ALLRPGR + ++ + LPD K R
Sbjct: 181 QSEQENTLNQLLVEMDGFNTQTGVVVLAATNRVDILDAALLRPGRFDRQIFVPLPDIKXR 360

Query: 404 LQILHIHTARMRGHQLLSADVDIKELAVETKNFSGAELEGLVRAA 448
             I  +H   ++    ++ +   +++A  T  FSGA++  +   A
Sbjct: 361 ASIFKVHLDPLKTE--VNKNDLARKMAALTPGFSGADIANVCNEA 489
>00810
          Length = 1431

 Score = 80.1 bits (196), Expect = 3e-15,   Method: Compositional matrix adjust.
 Identities = 71/233 (30%), Positives = 113/233 (48%), Gaps = 2/233 (0%)
 Frame = -3

Query: 228  SDIFRRAFASRVFPPEIVEQMGCKHVKGILLYGPPGCGKTLLARQIGKMLNAREPKVVNG 287
            +D+FR +  S + PP           KG+LL+GPPGCGKT++A+   K   AR    +  
Sbjct: 1375 ADLFRHS--SLLQPP-----------KGVLLHGPPGCGKTMIAKATAKAAGARFIN-LQV 1238

Query: 288  PEILNKYVGESEANIRKLFADAEEEQRRLGANSGLHIIIFDEIDAICKQRGSMAGSTGVH 347
              +++K+ GES+     +F+ A + Q          II  DEID+  + R S        
Sbjct: 1237 SSLVDKWYGESQKRAEAVFSLAIKLQPT--------IIFIDEIDSFLRSRTSTDHEATA- 1085

Query: 348  DTVVNQLLSKIDGV--EQLNNILVIGMTNRPDLIDEALLRPGRLEVKMEIGLPDEKGRLQ 405
              +  Q +S  DG+  +    ++V+G TNRP  +D A+LR  R+     IGLP    R  
Sbjct: 1084 -MIKTQFMSFWDGLMTDPDCRVMVMGATNRPQDVDAAILR--RMPSMFHIGLPGPAQRRS 914

Query: 406  ILHIHTARMRGHQLLSADVDIKELAVETKNFSGAELEGLVRAAQSTAMNRHIK 458
            I ++  ++ R   L     +  ELA  T  FSG+++  + RAA    ++  I+
Sbjct: 913  IFNLILSKERIDAL-----NYDELAEMTDGFSGSDIREVCRAAAVATVHEFIQ 770

 Score = 30.0 bits (66), Expect = 3.5,   Method: Compositional matrix adjust.
 Identities = 25/78 (32%), Positives = 38/78 (48%), Gaps = 3/78 (3%)
 Frame = -3

Query: 535  PLVSVLLEGPPHSGKTALAAKIAEESNFPFIKI---CSPDKMIGFSETAKCQAMKKIFDD 591
            P   VLL GPP  GKT +A   A+ +   FI +      DK  G S+    +  + +F  
Sbjct: 1342 PPKGVLLHGPPGCGKTMIAKATAKAAGARFINLQVSSLVDKWYGESQ----KRAEAVFSL 1175

Query: 592  AYKSQLSCVVVDDIERLL 609
            A K Q + + +D+I+  L
Sbjct: 1174 AIKLQPTIIFIDEIDSFL 1121
>20270
          Length = 542

 Score = 77.0 bits (188), Expect = 2e-14,   Method: Compositional matrix adjust.
 Identities = 47/136 (34%), Positives = 71/136 (52%), Gaps = 1/136 (0%)
 Frame = -3

Query: 251 KHVKGILLYGPPGCGKTLLARQIGKMLNAREPKVVNGPEILNKYVGESEANIRKLFADAE 310
           K  +GILLYGPPG GK+ LA+ +    N      V+  ++++K++GESE  ++ LF  A 
Sbjct: 387 KPWRGILLYGPPGTGKSYLAKAVATEANNSTFFSVSSSDLVSKWLGESEKLVKTLFQLAR 208

Query: 311 EEQRRLGANSGLHIIIFDEIDAICKQRGSMAGSTGVHDTVVNQLLSKIDGVEQLNN-ILV 369
           E Q          II  DE+DA+C  R      +     +  + L ++ GV   N  +LV
Sbjct: 207 ENQP--------SIIFIDEVDALCGSRSENESESARR--IKTEFLVQMQGVGNDNTGVLV 58

Query: 370 IGMTNRPDLIDEALLR 385
           +G TN P  +D A+ R
Sbjct: 57  LGATNIPWTLDSAIRR 10
>02194
          Length = 1891

 Score = 57.4 bits (137), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 46/155 (29%), Positives = 70/155 (45%), Gaps = 4/155 (2%)
 Frame = -1

Query: 242  PEIVEQMGCKHVKGILLYGPPGCGKTLLARQIGKMLNAREPKVVNGPEILNKYVGESEAN 301
            P      G  + +G LLYGPPGCGK+     +   L+     V+N  E      G S+  
Sbjct: 1531 PRWYMDRGIPYRRGYLLYGPPGCGKSSYIMALAGALD-YNICVLNLSE-----KGLSDDR 1370

Query: 302  IRKLFADAEEEQRRLGANSGLHIIIFDEIDAICKQRG----SMAGSTGVHDTVVNQLLSK 357
            +  L   A E+           II+ +++DA    R     + A   G+     + LL+ 
Sbjct: 1369 LNHLLTVAPEQS----------IILLEDVDAAFLSRDLSKENPAMYQGMGRLTFSGLLNA 1220

Query: 358  IDGVEQLNNILVIGMTNRPDLIDEALLRPGRLEVK 392
            +DGV      +V   TN  D +D AL+RPGR+++K
Sbjct: 1219 LDGVASAEARIVFMTTNYLDRLDPALIRPGRVDMK 1115
>17843
          Length = 772

 Score = 55.1 bits (131), Expect = 9e-08,   Method: Compositional matrix adjust.
 Identities = 42/153 (27%), Positives = 72/153 (47%), Gaps = 10/153 (6%)
 Frame = +1

Query: 256 ILLYGPPGCGKTLLARQIGKMLNAR--------EPKVVNGPEILNKYVGESEANIRKLFA 307
           ILL+GPPG GKT L + +   L  R        +   +N   + +K+  ES   + K+F 
Sbjct: 193 ILLHGPPGTGKTTLCKALAHKLCIRLSHRFSCGQLVEINSHSLFSKWFSESGKLVTKMF- 369

Query: 308 DAEEEQRRLGANSGLHIIIFDEIDAICKQRGSMAGSTGVHDT--VVNQLLSKIDGVEQLN 365
             +     +     L  ++ DE++++   R S        D   VVN +L++ID +++  
Sbjct: 370 --QRLHDYMVDPELLVCVLIDEVESLTAARKSCLNGNEPSDAIRVVNAVLTQIDQLKKFA 543

Query: 366 NILVIGMTNRPDLIDEALLRPGRLEVKMEIGLP 398
           N L++  +N    ID A +   R ++K  IG P
Sbjct: 544 NCLILTTSNITGAIDLAFV--DRADIKQYIGPP 636
>26408
          Length = 463

 Score = 47.8 bits (112), Expect = 2e-05,   Method: Composition-based stats.
 Identities = 19/33 (57%), Positives = 24/33 (72%)
 Frame = +1

Query: 242 PEIVEQMGCKHVKGILLYGPPGCGKTLLARQIG 274
           PE+ + +G    KG+LLYGPPG GKTLLAR + 
Sbjct: 331 PELFDALGIAQPKGVLLYGPPGTGKTLLARAVA 429
>25671
          Length = 441

 Score = 47.4 bits (111), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 41/120 (34%), Positives = 58/120 (48%), Gaps = 8/120 (6%)
 Frame = +2

Query: 265 GKTLLARQIGKMLNAREPKVVNGPEILNKYVGESEANIRKLFADAEEEQRRLGANSGLHI 324
           GKT+LA+ +          V     + NKY GESE  +R LF     E     A S    
Sbjct: 5   GKTMLAKAVATECGTTFFNVSTS-SLANKYRGESEKLVRLLF-----EMAHFYAPS---T 157

Query: 325 IIFDEIDAICKQRGSMAGSTGVHDT---VVNQLLSKIDGVEQLNN-----ILVIGMTNRP 376
           I  DEID+IC +RGS +     H+    V ++LL ++DGV   N+     ++V+  TN P
Sbjct: 158 IFIDEIDSICSKRGSDS----EHEASRRVKSELLVQMDGVGVTNDDPSKAVMVLAATNFP 325
>14413
          Length = 826

 Score = 47.0 bits (110), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 48/189 (25%), Positives = 88/189 (46%), Gaps = 16/189 (8%)
 Frame = +2

Query: 285 VNGPEILNKYVGESEANIRKLFADAEEEQRRLGAN-SGLHIIIFDEIDAICKQRGSMAGS 343
           +N   + +K+  ES   + +LF    E    L  + + L  ++ DE++++   R +M+ S
Sbjct: 83  INSHSLFSKWFSESGKLVARLFGKIGE----LATDKNNLVCVLIDEVESLAYARSAMS-S 247

Query: 344 TGVHDT--VVNQLLSKIDGVEQLNNILVIGMTNRPDLIDEALLRPGRLEVKMEIGLPDEK 401
               D   VVN +L+++D ++   N+L++  +N    ID A L   R +++  IGLPD  
Sbjct: 248 NEPRDAMRVVNAVLTQLDEIKACPNVLILATSNLAQSIDLAFL--DRADIRQFIGLPDP- 418

Query: 402 GRLQILHIHTARM---------RGHQLLSADVDIK----ELAVETKNFSGAELEGLVRAA 448
             L I  I+ + +         R  +L +++ D K     LA  +   SG  L  L   A
Sbjct: 419 --LAISSIYKSMLTELMVRGIVRTEELETSEADYKITLSNLAANSTGLSGRTLRKLPLLA 592

Query: 449 QSTAMNRHI 457
            +   +R +
Sbjct: 593 HAQHTSREL 619
>01279
          Length = 2183

 Score = 33.9 bits (76), Expect = 0.27,   Method: Compositional matrix adjust.
 Identities = 24/71 (33%), Positives = 38/71 (53%), Gaps = 2/71 (2%)
 Frame = -3

Query: 524  LVQQTKNSDRTPLVSVLLEGPPHSGKTALAAKIAEE--SNFPFIKICSPDKMIGFSETAK 581
            L++  K + R    +VLL GPP +GKTA+A  IA+E  +  PF  +   +  +  SE  K
Sbjct: 1941 LIKTKKMAGR----AVLLAGPPGTGKTAIALAIAQELGNKVPFCPMVGSE--VYSSEIKK 1780

Query: 582  CQAMKKIFDDA 592
             + + + F  A
Sbjct: 1779 TEVLMENFRRA 1747

 Score = 31.6 bits (70), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 17/41 (41%), Positives = 24/41 (58%), Gaps = 2/41 (4%)
 Frame = -3

Query: 244  IVEQMGCKHVKG--ILLYGPPGCGKTLLARQIGKMLNAREP 282
            +VE +  K + G  +LL GPPG GKT +A  I + L  + P
Sbjct: 1950 VVELIKTKKMAGRAVLLAGPPGTGKTAIALAIAQELGNKVP 1828
>19561
          Length = 474

 Score = 30.0 bits (66), Expect = 3.2,   Method: Compositional matrix adjust.
 Identities = 25/82 (30%), Positives = 39/82 (47%), Gaps = 7/82 (8%)
 Frame = -1

Query: 257 LLYGPPGCGKTLLARQIGKM-------LNAREPKVVNGPEILNKYVGESEANIRKLFADA 309
           LL GPPG GKT LA  + K        +NA + + V   E+ +  + E+   +R +    
Sbjct: 369 LLCGPPGLGKTTLAHIVAKHAGYNVVEMNASDDRSV---EVFSNKI-EAATQMRAV---- 214

Query: 310 EEEQRRLGANSGLHIIIFDEID 331
                 +GA+   + +I DEID
Sbjct: 213 ------MGADPRPNCLIIDEID 166
>27434
          Length = 472

 Score = 29.3 bits (64), Expect = 5.9,   Method: Compositional matrix adjust.
 Identities = 18/47 (38%), Positives = 22/47 (46%), Gaps = 2/47 (4%)
 Frame = +2

Query: 233 RAFASRVFPPEIVEQMGCKHVKGILL--YGPPGCGKTLLARQIGKML 277
           +    RV     V QM    +KG +L   GPPG GKT + R I   L
Sbjct: 95  KKLKKRVLEFLAVRQMKTTQLKGPILCFVGPPGVGKTSIGRSIATTL 235
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|33859751|ref|NP_077774.1| RAB21, member RAS oncogene
family [Mus musculus]
         (222 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

08428                                                                 148   1e-36
33374                                                                 114   9e-33
26083                                                                 113   7e-26
07465                                                                 110   5e-25
34468                                                                 103   7e-23
14456                                                                 102   2e-22
17511                                                                  99   1e-21
05468                                                                  90   7e-19
01972                                                                  71   1e-16
07580                                                                  82   2e-16
33794                                                                  81   3e-16
33380                                                                  81   3e-16
19006                                                                  80   6e-16
11728                                                                  79   1e-15
01398                                                                  77   4e-15
13901                                                                  77   5e-15
32723                                                                  77   8e-15
11257                                                                  77   8e-15
01095                                                                  76   9e-15
35581                                                                  75   3e-14
30760                                                                  75   3e-14
26536                                                                  74   7e-14
13750                                                                  72   1e-13
19656                                                                  71   3e-13
29380                                                                  70   8e-13
13745                                                                  65   2e-11
00858                                                                  64   5e-11
09204                                                                  64   6e-11
12339                                                                  62   1e-10
34359                                                                  61   4e-10
27191                                                                  60   1e-09
14119                                                                  54   7e-08
31291                                                                  52   2e-07
19046                                                                  47   5e-06
25618                                                                  47   9e-06
00552                                                                  46   1e-05
24619                                                                  45   2e-05
34597                                                                  44   5e-05
10708                                                                  44   6e-05
09827                                                                  44   6e-05
14775                                                                  42   2e-04
08153                                                                  41   3e-04
18509                                                                  37   0.008
33605                                                                  37   0.008
10862                                                                  36   0.013
>08428
          Length = 1109

 Score =  148 bits (374), Expect = 1e-36,   Method: Compositional matrix adjust.
 Identities = 70/160 (43%), Positives = 101/160 (63%)
 Frame = -3

Query: 19   KVVLLGEGCVGKTSLVLRYCENKFNDKHITTLQASFLTKKLNIGGKRVNLAIWDTAGQER 78
            KV LLG+  VGK+S+VLR+    +     +T+ ASF++K L + G      IWDTAGQE+
Sbjct: 1065 KVCLLGDSGVGKSSIVLRFVTGSYRPSQESTIGASFMSKSLVVDGAGYRFQIWDTAGQEK 886

Query: 79   FHALGPIYYRDSNGAILVYDVTDEDSFQKVKNWVKELRKMLGNEICLCIVGNKIDLEKER 138
            F AL P+YYR +  A++VYDVT   +F+ VK+W++ELR      I L I GNK DLE+ R
Sbjct: 885  FRALAPMYYRGAAAAVIVYDVTRPRTFKSVKSWIQELRSFGPPNIVLAIAGNKCDLEELR 706

Query: 139  HVSIQEAESYAESVGAKHYHTSAKQNKGIEELFLDLCKRM 178
             V  ++A+ YA S+ A    TSA     +EE+F +L +++
Sbjct: 705  EVVEKDAQEYASSISAIFGETSAMTAVNVEEMFTELARQL 586
>33374
          Length = 489

 Score =  114 bits (285), Expect(2) = 9e-33,   Method: Compositional matrix adjust.
 Identities = 50/117 (42%), Positives = 74/117 (63%)
 Frame = +1

Query: 54  FLTKKLNIGGKRVNLAIWDTAGQERFHALGPIYYRDSNGAILVYDVTDEDSFQKVKNWVK 113
           FLT+ + +    V   IWDTAGQER+H+L P+YYR +  AI+VYD+T++D+F + K WVK
Sbjct: 139 FLTQTVCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNQDTFGRAKTWVK 318

Query: 114 ELRKMLGNEICLCIVGNKIDLEKERHVSIQEAESYAESVGAKHYHTSAKQNKGIEEL 170
           EL++     I + + GNK DL  +R V  +EA++YAE        TSAK    + ++
Sbjct: 319 ELQRQASPNIVIALAGNKADLANKRMVEFEEAQAYAEENSLLFMETSAKTAMNVNDI 489

 Score = 42.7 bits (99), Expect(2) = 9e-33,   Method: Compositional matrix adjust.
 Identities = 19/37 (51%), Positives = 29/37 (78%)
 Frame = +2

Query: 18 FKVVLLGEGCVGKTSLVLRYCENKFNDKHITTLQASF 54
          FK+VLLGE  VGK+SLVLR+ + +F++   +T+ A+F
Sbjct: 32 FKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAF 142
>26083
          Length = 432

 Score =  113 bits (282), Expect = 7e-26,   Method: Compositional matrix adjust.
 Identities = 48/114 (42%), Positives = 78/114 (68%)
 Frame = +1

Query: 18  FKVVLLGEGCVGKTSLVLRYCENKFNDKHITTLQASFLTKKLNIGGKRVNLAIWDTAGQE 77
           FK+V LGE  VGKTSL+ R+  + F++ +  T+   FL+K + +  + + L +WDTAGQE
Sbjct: 79  FKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTIRLQLWDTAGQE 258

Query: 78  RFHALGPIYYRDSNGAILVYDVTDEDSFQKVKNWVKELRKMLGNEICLCIVGNK 131
           RF +L P Y RDS+ A++VYD+T+ +SF +   W+ ++R   G+++ + +VGNK
Sbjct: 259 RFRSLIPSYIRDSSVAVVVYDITNANSFHQTSKWIDDVRTERGSDVIIMLVGNK 420
>07465
          Length = 1103

 Score =  110 bits (275), Expect = 5e-25,   Method: Compositional matrix adjust.
 Identities = 53/149 (35%), Positives = 89/149 (59%)
 Frame = +3

Query: 31  TSLVLRYCENKFNDKHITTLQASFLTKKLNIGGKRVNLAIWDTAGQERFHALGPIYYRDS 90
           +S++ RYC+  F   +  T+   FL +++ +GG+ V L +WDTAGQE F A+   YYR +
Sbjct: 240 SSMIQRYCKGIFTKDYKKTIGVDFLERQIEVGGEDVRLMLWDTAGQEEFDAITKAYYRGA 419

Query: 91  NGAILVYDVTDEDSFQKVKNWVKELRKMLGNEICLCIVGNKIDLEKERHVSIQEAESYAE 150
              +L +   D DSF+ ++ W +++   +G EI + IV NKIDL  +  V  +EAE+ A+
Sbjct: 420 QACVLAFSTVDRDSFEALETWKRKVEDEVG-EIGMVIVQNKIDLIDDAVVRPEEAENLAK 596

Query: 151 SVGAKHYHTSAKQNKGIEELFLDLCKRMI 179
            +  + Y TS K+N  ++E+F  L  + +
Sbjct: 597 KLRLRFYRTSVKENMNVDEVFRYLADKYL 683
>34468
          Length = 1502

 Score =  103 bits (256), Expect = 7e-23,   Method: Compositional matrix adjust.
 Identities = 58/186 (31%), Positives = 101/186 (54%), Gaps = 10/186 (5%)
 Frame = +1

Query: 18  FKVVLLGEGCVGKTSLVLRYCENKFNDKHITTLQASFLTKKLNIGGKRVNLAIWDTAGQE 77
           FK++++G+  VGKT L  R+C  KF DK   T+   F  K + +  + + L +WDTAGQE
Sbjct: 496 FKIIVIGDSNVGKTCLTYRFCLGKFPDKTEATIGVDFREKSIQVDSEHLKLQLWDTAGQE 675

Query: 78  RFH-ALGPIYYRDSNGAILVYDVTDEDSFQKVKNWVKEL-RKMLGNEICLCIVGNKIDLE 135
           RF  ++   YYR+ +  + VYD+T   SF+ +  W++E  R  L   I   +VGNK D+ 
Sbjct: 676 RFRKSMVQHYYRNVHAVVFVYDMTKMSSFENMPAWIEECDRHNLTKYIPRILVGNKCDVV 855

Query: 136 KERHVSIQEAESYAESVGAKHYHTSAKQNKG---IEELFLDLCKRM-----IETAQVDER 187
           +   V+   A+ +A++     + TSAK ++    ++ +F+ +  ++     +  A + E 
Sbjct: 856 ERIAVNTNLAQKFADAHNMPLFETSAKDDEKANHVDAIFMTVAHKLKXSKPMMPAHLSEM 1035

Query: 188 AKGNGS 193
             G+ S
Sbjct: 1036VPGDVS 1053
>14456
          Length = 1867

 Score =  102 bits (253), Expect = 2e-22,   Method: Compositional matrix adjust.
 Identities = 64/185 (34%), Positives = 98/185 (52%), Gaps = 7/185 (3%)
 Frame = -1

Query: 23   LGEGCVGKTSLVLRYCENKFNDKHITTLQASFLTKKLNIGGKRVNLAIWDTAGQERFHAL 82
            L +G VGK+SL+ R+  NKF+ +   T+   FL K + +  +   + IWDTAGQERF +L
Sbjct: 1123 LKQGGVGKSSLMNRFVSNKFDAQSFHTIGVEFLNKDVVVDDETYTMQIWDTAGQERFKSL 944

Query: 83   GPIYYRDSNGAILVYDVTDEDSFQKVKNWVKELRKML----GNEICLCIVGNKIDLEKER 138
               +YR ++  +L + V    SF+ +  W KE         G      ++GNKID+E  R
Sbjct: 943  RTPFYRGADCCLLTFSVDSMQSFRNLSMWRKEFLYYADIQDGVTFPFVVLGNKIDVEG-R 767

Query: 139  HVSIQEAESYAES-VGAKHYHTSAKQNKGIEELFLDLCKRM--IETAQVDERAKGNGSSQ 195
             V+ +EA S+  +   A ++ TSAK    +E+ FL   +R+  +E  Q  + A GN    
Sbjct: 766  QVTNEEARSWCTANSNAPYFETSAKDATNVEKAFLAAVQRLREVEDQQEVKTAHGNTVDL 587

Query: 196  AGAAR 200
              AAR
Sbjct: 586  NRAAR 572
>17511
          Length = 483

 Score = 99.4 bits (246), Expect = 1e-21,   Method: Compositional matrix adjust.
 Identities = 48/120 (40%), Positives = 76/120 (63%), Gaps = 4/120 (3%)
 Frame = -3

Query: 19  KVVLLGEGCVGKTSLVLRYCENKFNDKHITTLQASFLTKKLNIGGKRVNLAIWDTAGQER 78
           KV++LG+  VGKTSL+ +Y   KF++++  T+ A FLTK++ +  + V + IWDTAGQER
Sbjct: 361 KVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQIWDTAGQER 182

Query: 79  FHALGPIYYRDSNGAILVYDVTDEDSFQKVKNWVKELRKMLG----NEICLCIVGNKIDL 134
           F +LG  +YR ++  +LV+DVT  ++F+ + +W  E                ++GNKIDL
Sbjct: 181 FQSLGVAFYRGADCCVLVFDVTMPNTFRSLDSWRDEFLIQASPRDPENFPFVVIGNKIDL 2
>05468
          Length = 1558

 Score = 89.7 bits (221), Expect = 7e-19,   Method: Compositional matrix adjust.
 Identities = 57/170 (33%), Positives = 89/170 (52%), Gaps = 7/170 (4%)
 Frame = -3

Query: 18   FKVVLLGEGCVGKTSLVLRYCENKFNDKHITTLQASFLTKKLNIGGKR-VNLAIWDTAGQ 76
            +K++++GE   GKTS++ RY    F+  +  T+   F  K LN      + L +WD AGQ
Sbjct: 1538 YKILVIGELGTGKTSIIKRYVHQFFSQHYRATIGVDFALKVLNWDADTLIRLQLWDIAGQ 1359

Query: 77   ERFHALGPIYYRDSNGAILVYDVTDEDSFQKVKNWVKELRKML----GNEICLCIVGNKI 132
            ERF  +  +YY+++ GA +V+DVT   +F  V  W  +L   +    G+ +   ++ NK 
Sbjct: 1358 ERFGNMTRVYYKEAVGAFVVFDVTRASTFDAVTKWKNDLDSKVQLADGSPVPCVLLANKC 1179

Query: 133  DLEKERHV--SIQEAESYAESVGAKHYHTSAKQNKGIEELFLDLCKRMIE 180
            D  KE  V  + Q  E  +E      Y TSAK+N  I+E    L  R++E
Sbjct: 1178 DQAKEGLVNNTSQMDEFCSEKGFIGWYETSAKENINIDEAARFLVTRILE 1029
>01972
          Length = 2359

 Score = 70.9 bits (172), Expect(2) = 1e-16,   Method: Compositional matrix adjust.
 Identities = 43/136 (31%), Positives = 73/136 (53%), Gaps = 1/136 (0%)
 Frame = +3

Query: 45  KHITTLQASFLTKKLNIGGKRVNLAIWDTAGQERFHALGPIYYRDSNGAILVYDVTDEDS 104
           K++ TL         +    ++   +WDTAGQE+F  L   YY     A++++DVT   +
Sbjct: 384 KYVATLGVEVHPLLFHTSRGKLKFNVWDTAGQEKFGGLRDGYYIQGQCAVIMFDVTSRVT 563

Query: 105 FQKVKNWVKELRKMLGN-EICLCIVGNKIDLEKERHVSIQEAESYAESVGAKHYHTSAKQ 163
           ++ V NW ++L ++  N  I LC  GNK+D+ K+R V   +A  +      ++Y  SAK 
Sbjct: 564 YKNVPNWHRDLVRVCENIPIVLC--GNKVDI-KDRKVK-AKAIVFHRKKNLQYYDISAKS 731

Query: 164 NKGIEELFLDLCKRMI 179
           N   E+ FL L ++++
Sbjct: 732 NYNFEKPFLWLARKLV 779

 Score = 32.0 bits (71), Expect(2) = 1e-16,   Method: Compositional matrix adjust.
 Identities = 13/26 (50%), Positives = 20/26 (76%)
 Frame = +1

Query: 17  SFKVVLLGEGCVGKTSLVLRYCENKF 42
           +FK+VL+G+G VGKT+ V R+   +F
Sbjct: 301 TFKLVLVGDGGVGKTTFVKRHVTGEF 378
>07580
          Length = 921

 Score = 82.0 bits (201), Expect = 2e-16,   Method: Compositional matrix adjust.
 Identities = 46/146 (31%), Positives = 83/146 (56%), Gaps = 5/146 (3%)
 Frame = +3

Query: 38  CENKFNDKHITTLQASFLTKKLNIGGKRVNLAIWDTAGQERFHALGPIYYRDSNGAILVY 97
           C+  F +K+  T++ S+  K++ + G++  L I DTAG E+F A+  +Y ++  G +L Y
Sbjct: 123 CKGIFVEKYDPTIEDSY-RKQVEVDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFLLAY 299

Query: 98  DVTDEDSFQKVKNWVKELRKML-----GNEICLCIVGNKIDLEKERHVSIQEAESYAESV 152
            +T + +F    N ++ELR+ +      +++ + +VGNK DLE ER V   + +  A S 
Sbjct: 300 SITAQSTF----NDLQELREQILRVKDTDDVPMLLVGNKCDLEDERVVGKDQGQGLARSF 467

Query: 153 GAKHYHTSAKQNKGIEELFLDLCKRM 178
                 TSAK    + E+F+DL +++
Sbjct: 468 SCAFLETSAKARINVNEIFMDLVRQI 545
>33794
          Length = 779

 Score = 81.3 bits (199), Expect = 3e-16,   Method: Compositional matrix adjust.
 Identities = 51/142 (35%), Positives = 77/142 (54%), Gaps = 4/142 (2%)
 Frame = -1

Query: 39  ENKF---NDKHITTLQA-SFLTKKLNIGGKRVNLAIWDTAGQERFHALGPIYYRDSNGAI 94
           EN F   ND     LQ  ++ T  + + GKRV L IWDT+GQ RF  +   Y R + G I
Sbjct: 743 ENPFCSGNDCTSHILQTVAYKTTTILLEGKRVKLQIWDTSGQGRFCTIIRSYSRGAQGII 564

Query: 95  LVYDVTDEDSFQKVKNWVKELRKMLGNEICLCIVGNKIDLEKERHVSIQEAESYAESVGA 154
           LVYD+T++ SF  +  W+KE+ +     I   +VGN++ L  +R V+ ++AE+YA     
Sbjct: 563 LVYDITNKWSFDGIDRWLKEVEEH-APGIPKVLVGNRLHLAYKRQVAAKQAETYASRNNM 387

Query: 155 KHYHTSAKQNKGIEELFLDLCK 176
             +  S   +  I E F +L +
Sbjct: 386 SCFEISPLCDFNIRESFCELAR 321
>33380
          Length = 282

 Score = 80.9 bits (198), Expect = 3e-16,   Method: Compositional matrix adjust.
 Identities = 37/75 (49%), Positives = 51/75 (68%)
 Frame = +3

Query: 64  KRVNLAIWDTAGQERFHALGPIYYRDSNGAILVYDVTDEDSFQKVKNWVKELRKMLGNEI 123
           KRV L IWDTAGQER+  +   YYR + G IL+YDVT+E+SF  V++W  +++    +  
Sbjct: 54  KRVKLQIWDTAGQERYRTITTAYYRGAMGFILMYDVTNEESFNAVQDWCTQIKTYSWDNA 233

Query: 124 CLCIVGNKIDLEKER 138
            + +VGNK DLE ER
Sbjct: 234 QVVLVGNKCDLEDER 278
>19006
          Length = 568

 Score = 80.1 bits (196), Expect = 6e-16,   Method: Compositional matrix adjust.
 Identities = 37/122 (30%), Positives = 75/122 (61%), Gaps = 1/122 (0%)
 Frame = -2

Query: 19  KVVLLGEGCVGKTSLVLRYCENKFNDKHITTLQASFLTKKLNIGGKRVNLAIWDTAGQER 78
           K+V++G+G  GKT L++ + +++F + ++ T+  +++   + +  K+V LA+WDTAGQE 
Sbjct: 432 KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVAD-IEVDSKQVELALWDTAGQED 256

Query: 79  FHALGPIYYRDSNGAILVYDVTDEDSFQKV-KNWVKELRKMLGNEICLCIVGNKIDLEKE 137
           +  L P+ Y D++  ++ + +   DS + + + W  E+R    N + + +VGNK DL  +
Sbjct: 255 YDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVRHFCPN-VPIILVGNKKDLRND 79

Query: 138 RH 139
            +
Sbjct: 78  EN 73
>11728
          Length = 635

 Score = 79.3 bits (194), Expect = 1e-15,   Method: Compositional matrix adjust.
 Identities = 47/165 (28%), Positives = 87/165 (52%), Gaps = 14/165 (8%)
 Frame = -1

Query: 17  SFKVVLLGEGCVGKTSLVLRYCENKFNDKHITTLQASFLTKKLNIGGKRVNLAIWDTAGQ 76
           + K V++G+G VGKT L++ Y  N F  ++I T+  ++ +  + +  K +NL +WDTAGQ
Sbjct: 491 AIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNY-SANVMVDSKPINLGLWDTAGQ 315

Query: 77  ERFHALGPIYYRDSNGAILVYDVTDEDSFQKVK-NWVKELRKMLGNEICLCIVGNKIDLE 135
           E +  L P+ Y  ++  ++ + +    SF+ VK  W  E+     N   + +VG K+DL 
Sbjct: 314 EDYDRLRPLSYPQTDVFLICFSLISPASFENVKAKWYPEVSHHCPNTP-IILVGTKLDLR 138

Query: 136 KERH------------VSIQEAESYAESVGA-KHYHTSAKQNKGI 167
           +++             ++  +  + A+ +GA K+   SA   KG+
Sbjct: 137 EDKETIEKLKEKKLAPITYPQGLAMAKDIGAGKYLECSALTQKGL 3
>01398
          Length = 1421

 Score = 77.4 bits (189), Expect = 4e-15,   Method: Compositional matrix adjust.
 Identities = 38/102 (37%), Positives = 60/102 (58%), Gaps = 1/102 (0%)
 Frame = -2

Query: 76   QERFHALGPIYYRDSNGAILVYDVTDEDSFQKVKNWVKELRKML-GNEICLCIVGNKIDL 134
            QERF ++   YYR+S G I+VYD+T   +F+ +K W +E R  +  ++    ++G+K D 
Sbjct: 1420 QERFRSITRSYYRNSVGVIIVYDITKRSTFENLKQWYEEARNHIEPHKAIFLVLGHKSDR 1241

Query: 135  EKERHVSIQEAESYAESVGAKHYHTSAKQNKGIEELFLDLCK 176
            E  R V+ +E   +AE  G K + TSAK    IE++F  + K
Sbjct: 1240 EDARQVTAREGRRFAEMHGLKFFETSAKSGHNIEDVFAQIAK 1115
>13901
          Length = 962

 Score = 77.4 bits (189), Expect = 5e-15,   Method: Compositional matrix adjust.
 Identities = 34/95 (35%), Positives = 58/95 (61%), Gaps = 1/95 (1%)
 Frame = -3

Query: 18  FKVVLLGEGCVGKTSLVLRYCENKFNDKHITTLQASFLTKKLNIGGK-RVNLAIWDTAGQ 76
           FKV+++G+  VGKTS V RY  + F   +  T+   F  K +    K  + L +WD AGQ
Sbjct: 285 FKVIIIGDPTVGKTSFVQRYVNDSFRRDYKMTIGVDFALKVIRWSDKCNIKLQLWDIAGQ 106

Query: 77  ERFHALGPIYYRDSNGAILVYDVTDEDSFQKVKNW 111
           ERF ++  +YY+D++  I+++D+T ++++Q    W
Sbjct: 105 ERFTSMTRVYYKDAHACIVMFDLTQKNTYQNAIRW 1
>32723
          Length = 384

 Score = 76.6 bits (187), Expect = 8e-15,   Method: Compositional matrix adjust.
 Identities = 36/108 (33%), Positives = 59/108 (54%)
 Frame = +2

Query: 76  QERFHALGPIYYRDSNGAILVYDVTDEDSFQKVKNWVKELRKMLGNEICLCIVGNKIDLE 135
           QERF ++   YYR +N  ILVYDV  + S++ +  W+ E+    G ++   +VGNKID  
Sbjct: 2   QERFRSITQSYYRSANALILVYDVCSQQSYESLPQWIHEIELYAGTKVLAFLVGNKIDQT 181

Query: 136 KERHVSIQEAESYAESVGAKHYHTSAKQNKGIEELFLDLCKRMIETAQ 183
            +R +     + +AE    +   TSAK+   +E+LF  +  ++   AQ
Sbjct: 182 DKREIPTHIGKEFAERYEMRFLETSAKEADNVEKLFSTIAYQLTAQAQ 325
>11257
          Length = 1102

 Score = 76.6 bits (187), Expect = 8e-15,   Method: Compositional matrix adjust.
 Identities = 44/138 (31%), Positives = 75/138 (54%), Gaps = 6/138 (4%)
 Frame = -2

Query: 57   KKLNIGGKRVNLAIWDTAGQERFHALGPIYYRDSNGAILVYDVTDEDSFQKVKNWVKELR 116
            K + + G+   + IWDTAGQER+ +L   +YR ++  +L + V +  S Q + +W  E  
Sbjct: 1053 KDVVVDGETFTMQIWDTAGQERYKSLRTPFYRGTDCCLLTFSVDNLKSLQSLSDWYDEFV 874

Query: 117  KML----GNEICLCIVGNKIDLEKERHVSIQEAESYAESVG-AKHYHTSAKQNKGIEELF 171
                          I+GNK D+E ER VS ++A ++  + G   ++ TSAK +  +++ F
Sbjct: 873  NYADIQDSASFPFVIIGNKADIE-EREVSSEDAYNWCRTHGNLPYFETSAKDSLNVQQAF 697

Query: 172  LDLCKRMIET-AQVDERA 188
            L + +R+ E   Q+DER 
Sbjct: 696  LAVVRRLREMDEQMDERP 643
>01095
          Length = 1745

 Score = 76.3 bits (186), Expect = 9e-15,   Method: Compositional matrix adjust.
 Identities = 39/117 (33%), Positives = 68/117 (58%)
 Frame = -1

Query: 95   LVYDVTDEDSFQKVKNWVKELRKMLGNEICLCIVGNKIDLEKERHVSIQEAESYAESVGA 154
            +VYD+T++D+F + K WVKEL++     I + + GNK DL  +R V  +EA++YAE    
Sbjct: 1745 VVYDITNQDTFGRAKTWVKELQRQASPNIVIALAGNKADLANKRMVEFEEAQAYAEENSL 1566

Query: 155  KHYHTSAKQNKGIEELFLDLCKRMIETAQVDERAKGNGSSQAGAARRGVQIIDDEPQ 211
                TSAK    + ++FL + K++        + +G G SQ    ++GV++ +++ Q
Sbjct: 1565 LFMETSAKTAMNVNDIFLAIAKKL-------PKNEGGGGSQ--PRQQGVRLNNEQSQ 1422
>35581
          Length = 364

 Score = 74.7 bits (182), Expect = 3e-14,   Method: Compositional matrix adjust.
 Identities = 38/82 (46%), Positives = 51/82 (62%), Gaps = 1/82 (1%)
 Frame = +2

Query: 18  FKVVLLGEGCVGKTSLVLRYCENKFNDKHITTLQ-ASFLTKKLNIGGKRVNLAIWDTAGQ 76
           FK VLLG+  VGKT L+ R   +KF D  +T+L  AS LT      G   ++ +WDTAGQ
Sbjct: 47  FKCVLLGDAGVGKTCLLNRLATDKFLDSPLTSLTTASLLTTVTLTSGVMASVDLWDTAGQ 226

Query: 77  ERFHALGPIYYRDSNGAILVYD 98
           ER+ +L   YYRD+   ++VYD
Sbjct: 227 ERYRSLTSSYYRDTKAVLIVYD 292
>30760
          Length = 596

 Score = 74.7 bits (182), Expect = 3e-14,   Method: Compositional matrix adjust.
 Identities = 50/161 (31%), Positives = 82/161 (50%), Gaps = 5/161 (3%)
 Frame = -1

Query: 19  KVVLLGEGCVGKTSL--VLRYCENKFNDKHITTLQASFLTKKLNIGGKR--VNLAIWDTA 74
           K ++ G+  VGK+S+  V       F   +  T     L K +NI   R  V L ++D+A
Sbjct: 524 KCIVTGDSGVGKSSICQVFHSDSAHFPKNYSMTTGVEVLVKLVNIPDSRDQVELYLFDSA 345

Query: 75  GQERFHALGPIYYRDSNGAILVYDVTDEDSFQKVKNWVKELRKMLGNEICL-CIVGNKID 133
           G+E F      ++   +  ++VYDVTDE SF     W++ +R    N +    +V NK D
Sbjct: 344 GKEIFSENVTKFWDQPSVVMVVYDVTDETSFSGCVRWLERVRAAKPNTVIPGVLVANKTD 165

Query: 134 LEKERHVSIQEAESYAESVGAKHYHTSAKQNKGIEELFLDL 174
           L++ R VS +E +  A+S G +++  SAK+ +  +  F  L
Sbjct: 164 LDERRRVSRKEGKDLAQSHGLEYFECSAKEMQNTDTPFFCL 42
>26536
          Length = 829

 Score = 73.6 bits (179), Expect = 7e-14,   Method: Compositional matrix adjust.
 Identities = 50/164 (30%), Positives = 79/164 (48%), Gaps = 3/164 (1%)
 Frame = +2

Query: 48  TTLQASFLTKKLNIGGKRVNLAIWDTAGQERFHALGPIYYRDSNGAILVYDVTDEDSFQK 107
           T +  S  T K+ +  +RV+    DTAGQE + ++   Y R  +G I+VY VTD  SFQ+
Sbjct: 77  TIMLLSLTTMKMMME-RRVSWTFLDTAGQEEYSSMREHYTRSGDGFIVVYSVTDVTSFQE 253

Query: 108 ---VKNWVKELRKMLGNEICLCIVGNKIDLEKERHVSIQEAESYAESVGAKHYHTSAKQN 164
              V  W+   +        LC  GNK DL  +R V+ +E    A+ +G  ++ TSAK  
Sbjct: 254 AEAVFRWLTRFQDETSIHAVLC--GNKTDLTSDRKVTPEEGRKMADRLGMLYFETSAKTG 427

Query: 165 KGIEELFLDLCKRMIETAQVDERAKGNGSSQAGAARRGVQIIDD 208
             + +++  L  R I  +  D +    GS   G +   ++   D
Sbjct: 428 DNVSQVYHGLL-RSIPRSGTDYKIVMLGSGGVGKSSLTIRFTQD 556
>13750
          Length = 503

 Score = 72.4 bits (176), Expect = 1e-13,   Method: Compositional matrix adjust.
 Identities = 47/149 (31%), Positives = 77/149 (51%), Gaps = 4/149 (2%)
 Frame = -2

Query: 30  KTSLVLRYCENKFNDKHITTLQASFLTKKLN---IGGKRVNLAIWDTAGQERFHALGPIY 86
           KT L+ RY +  F D+ + T+  + L  + N        V   +WDT G E + +L   +
Sbjct: 502 KTCLLRRYQKGFFMDRTMPTI--AVLCSEFNESRTDPLNVRYTLWDTGGAETYRSLWVSH 329

Query: 87  YRDSNGAILVYDVTDEDSFQKVKN-WVKELRKMLGNEICLCIVGNKIDLEKERHVSIQEA 145
           +R +  A+LVYDVT E SF      W K L K +  E  +  VG+K DLE+ R +S +  
Sbjct: 328 FRGAQVALLVYDVTCEWSFLTATTVWRKALMKNIP-EAQVIFVGSKTDLEENRVISTERG 152

Query: 146 ESYAESVGAKHYHTSAKQNKGIEELFLDL 174
           +++A   G   + TS+   K ++ +F ++
Sbjct: 151 QAFATQCGYTFFETSSVTGKNVDAVFWEI 65
>19656
          Length = 428

 Score = 71.2 bits (173), Expect = 3e-13,   Method: Compositional matrix adjust.
 Identities = 34/100 (34%), Positives = 60/100 (60%), Gaps = 1/100 (1%)
 Frame = +3

Query: 17  SFKVVLLGEGCVGKTSLVLRYCENKFNDKHITTLQASFLTKKLNIGGKRVNLAIWDTAGQ 76
           + K V++G+G VGKT L++ Y  N F  ++I T+  ++ +  + + G+ VNL +WDTAGQ
Sbjct: 111 AIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNY-SANVMVDGRPVNLGLWDTAGQ 287

Query: 77  ERFHALGPIYYRDSNGAILVYDVTDEDSFQKVK-NWVKEL 115
           E +  L P+ Y  ++  +L + V    SF+ ++  W  E+
Sbjct: 288 EDYDRLRPLSYPQTDVFLLCFSVASPASFENIRAKWYPEV 407
>29380
          Length = 853

 Score = 69.7 bits (169), Expect = 8e-13,   Method: Compositional matrix adjust.
 Identities = 33/92 (35%), Positives = 54/92 (58%), Gaps = 1/92 (1%)
 Frame = -2

Query: 90  SNGAILVYDVTDEDSFQKVKNWVKELRKMLGNEICLCIVGNKIDLEKE-RHVSIQEAESY 148
           ++ AI+VYDV   D+F +   WVKELR+     + + + GNK+DL  + R VS ++A+S+
Sbjct: 852 ASAAIIVYDVNIADTFSRALAWVKELRQQNTESVLIILAGNKVDLATQHRAVSFEDAQSF 673

Query: 149 AESVGAKHYHTSAKQNKGIEELFLDLCKRMIE 180
           A   G      SAK    + E+F+ L  ++I+
Sbjct: 672 ARENGLLFAEVSAKTGMAVNEIFMTLANQLIQ 577
>13745
          Length = 1045

 Score = 65.1 bits (157), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 37/110 (33%), Positives = 59/110 (53%), Gaps = 5/110 (4%)
 Frame = +2

Query: 76  QERFHALGPIYYRDSNGAILVYDVTDEDSFQKVKNWVKEL----RKMLGNEICLCIVGNK 131
           QERF +LG  +YR ++  +LVYDVT  +SF+ + +W  E                ++GNK
Sbjct: 2   QERFQSLGVAFYRGADCCVLVYDVTAPNSFKNLDSWRDEFLIQASPRDPEHFPFVVLGNK 181

Query: 132 IDLEKERHVSIQEAESYAESVG-AKHYHTSAKQNKGIEELFLDLCKRMIE 180
           +DL+  R VS + A+ + +S     +Y TSAK+   +E  F  + K  +E
Sbjct: 182 VDLDN-RQVSTRRAQQWCQSKNDIPYYETSAKEGINVEMAFQTIAKNALE 328
>00858
          Length = 1658

 Score = 63.9 bits (154), Expect = 5e-11,   Method: Compositional matrix adjust.
 Identities = 42/150 (28%), Positives = 83/150 (55%), Gaps = 1/150 (0%)
 Frame = -2

Query: 30   KTSLVLRYCENKFNDKHITTLQASFLTKKLNIGGKRVNLAIWDTAGQERFHALGPIYYRD 89
            K++L ++  +N F +++  T + S   K++ I G+   L I DTAGQE   A+     R 
Sbjct: 1552 KSALTIQLXQNHFVEEYDPTXEDS-XRKQVVIDGETCLLDILDTAGQEEXSAMRDQCMRT 1376

Query: 90   SNGAILVYDVTDEDSFQKVKNWVKELRKML-GNEICLCIVGNKIDLEKERHVSIQEAESY 148
              G + V+ V +  SF+ +  + ++++++   +E+ + +VGNK+DL   R+V  ++ +  
Sbjct: 1375 GEGFLCVFAVXNLKSFEDINQYREQIKRVKDADEVPMVLVGNKVDLPI-RNVEQRQGKHM 1199

Query: 149  AESVGAKHYHTSAKQNKGIEELFLDLCKRM 178
            AE     +  TSAK  +G+++ F  L + +
Sbjct: 1198 AELYHIPYVETSAKTRQGVDDAFYTLVREI 1109
>09204
          Length = 1051

 Score = 63.5 bits (153), Expect = 6e-11,   Method: Compositional matrix adjust.
 Identities = 37/98 (37%), Positives = 55/98 (56%), Gaps = 4/98 (4%)
 Frame = -3

Query: 78   RFHALGPIYYRDSNGAILVYDVTDEDSFQKVKNWVKELRKMLGNEICLCIVGNKIDL--- 134
            R+ A+  IYYR +  AIL +D+TD+ SF +++ W+ ELR+    E  L I G K DL   
Sbjct: 1049 RYEAMSRIYYRGAKAAILCFDLTDKSSFDRIRFWIGELRQH-EEECKLYICGTKFDLVHD 873

Query: 135  -EKERHVSIQEAESYAESVGAKHYHTSAKQNKGIEELF 171
              + R V    A++ A+   A+ Y TS+     IE+LF
Sbjct: 872  DPERRAVPRSVAKALADDCMAEIYETSSMTGDNIEKLF 759
>12339
          Length = 578

 Score = 62.4 bits (150), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 34/109 (31%), Positives = 58/109 (53%), Gaps = 5/109 (4%)
 Frame = -2

Query: 76  QERFHALGPIYYRDSNGAILVYDVTDEDSFQKVKNWVKELRKMLG----NEICLCIVGNK 131
           QERF +LG  +YR ++  ILVYDVT+  +F  + +W +E                ++GNK
Sbjct: 577 QERFQSLGVAFYRGADCCILVYDVTEXKTFDSLDSWQREFLNQASPRDPEHFPFVVIGNK 398

Query: 132 IDLEKERHVSIQEAESYAESVGA-KHYHTSAKQNKGIEELFLDLCKRMI 179
           IDL+  R V+ +  + +  + G   ++ TSAK+   +E+ F  + K  +
Sbjct: 397 IDLDN-RVVTAKRGQGWCSTKGGIPYFETSAKEAINVEQAFQTVAKNAL 254
>34359
          Length = 1042

 Score = 60.8 bits (146), Expect = 4e-10,   Method: Compositional matrix adjust.
 Identities = 42/125 (33%), Positives = 67/125 (53%), Gaps = 1/125 (0%)
 Frame = +3

Query: 17  SFKVVLLGEGCVGKTSLVLRYCENKFNDKHITTLQASFLTKKLNIGGKRVNLAIWDTAGQ 76
           +FK+VL+G       ++V R+       K++ TL       + N     +   +WDTAGQ
Sbjct: 51  NFKLVLVGGRWEWANNIVKRHVTGS*K-KYVATLGVEVHPLQFNTSRGLLRFNVWDTAGQ 227

Query: 77  ERFHALGPIYYRDSNGAILVYDVTDEDSFQKVKNWVKELRKMLGN-EICLCIVGNKIDLE 135
           E+F  L   YY     AI+++DVT   +++ V NW ++L ++  N  I LC  GNK+D+ 
Sbjct: 228 EKFGGLRDGYYIQGTCAIIMFDVTSRVTYKNVPNWHRDLVRVCENIPIVLC--GNKVDI- 398

Query: 136 KERHV 140
           K+R V
Sbjct: 399 KDRKV 413
>27191
          Length = 443

 Score = 59.7 bits (143), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 30/118 (25%), Positives = 59/118 (50%)
 Frame = +1

Query: 30  KTSLVLRYCENKFNDKHITTLQASFLTKKLNIGGKRVNLAIWDTAGQERFHALGPIYYRD 89
           KT L+  +CE+KFN  +  T+   +  K   + G  + + +WD +G   +  +    Y  
Sbjct: 1   KTCLIKHFCESKFNQGYQPTVGVDYGFKIQTVNGVDMRVHMWDLSGSNEYLDVRNELYTG 180

Query: 90  SNGAILVYDVTDEDSFQKVKNWVKELRKMLGNEICLCIVGNKIDLEKERHVSIQEAES 147
           S+   +V+DV++  SF+ + +W++E+ +         IVGN++   +      Q+ ES
Sbjct: 181 SDAIFIVFDVSNTPSFEALDSWLREINRFATGSPLNVIVGNRVI*NRSAQCRQQKQES 354
>14119
          Length = 602

 Score = 53.5 bits (127), Expect = 7e-08,   Method: Compositional matrix adjust.
 Identities = 26/81 (32%), Positives = 43/81 (53%), Gaps = 1/81 (1%)
 Frame = +1

Query: 104 SFQKVKNWVKELRKMLGNEICLCIVGNKIDLEKE-RHVSIQEAESYAESVGAKHYHTSAK 162
           +F +   WVKELR+     + + + GNK DL  E R VS  +A ++AE  G      SAK
Sbjct: 1   TFNRALAWVKELRQQNAGSVLIVLAGNKADLASEHRAVSADDARTFAEDNGLIFAEVSAK 180

Query: 163 QNKGIEELFLDLCKRMIETAQ 183
               + E+F+ +  +++  A+
Sbjct: 181 TGMAVSEVFMTIAHKLVRRAE 243
>31291
          Length = 446

 Score = 52.0 bits (123), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 33/118 (27%), Positives = 59/118 (50%), Gaps = 14/118 (11%)
 Frame = -1

Query: 68  LAIWDTAGQERFHALGPIYYRDSNGAILVYDVTDEDSFQKVK-NWVKELRKMLGNEICLC 126
           L +WDTAGQE +  L P+ Y +++  +L + +  E S + VK  W  E+R      + + 
Sbjct: 446 LQLWDTAGQEDYDRLRPLAYPNTDVFMLXFSLMSEASMKNVKVKWYPEIRHH-DPHVPIV 270

Query: 127 IVGNKIDLEKERH------------VSIQEAESYAESVGAKHY-HTSAKQNKGIEELF 171
           +VG K+DL +++             VS  +    A+++ AK Y   S+K  + ++  F
Sbjct: 269 LVGTKLDLRQDKEAVRKLRSSRQDPVSSNQGNDLAKAIKAKRYFECSSKTQENLKTAF 96
>19046
          Length = 445

 Score = 47.4 bits (111), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 29/88 (32%), Positives = 46/88 (52%), Gaps = 1/88 (1%)
 Frame = -2

Query: 76  QERFHALGPIYYRDSNGAILVYDVTDEDSFQKVKNW-VKELRKMLGNEICLCIVGNKIDL 134
           QE F A+   Y R  +G +LV+ VTD  SF+ + N+  + LR    +   + +  NK+DL
Sbjct: 444 QEEFSAMREQYMRKGDGFLLVFSVTDFRSFENMANFHTQILRVKDRDSYPMILCANKVDL 265

Query: 135 EKERHVSIQEAESYAESVGAKHYHTSAK 162
             +R VS ++    A  +   +  TSAK
Sbjct: 264 VHQRKVSEEQVRDLATRLRIPYIETSAK 181
>25618
          Length = 475

 Score = 46.6 bits (109), Expect = 9e-06,   Method: Compositional matrix adjust.
 Identities = 27/84 (32%), Positives = 43/84 (51%), Gaps = 1/84 (1%)
 Frame = +3

Query: 113 KELRKMLGNEICLCIVGNKIDLEKE-RHVSIQEAESYAESVGAKHYHTSAKQNKGIEELF 171
           KELR+     + + + GNK DL  E R VS  +A ++AE  G      SAK    + E+F
Sbjct: 48  KELRQQNAGSVLIVLAGNKADLASEHRAVSADDARTFAEDNGLIFAEVSAKTGMAVSEVF 227

Query: 172 LDLCKRMIETAQVDERAKGNGSSQ 195
           + +  +++  A+     +G GS Q
Sbjct: 228 MTIAHKLVRRAE-----EGQGSXQ 284
>00552
          Length = 455

 Score = 45.8 bits (107), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 22/51 (43%), Positives = 33/51 (64%)
 Frame = -1

Query: 18  FKVVLLGEGCVGKTSLVLRYCENKFNDKHITTLQASFLTKKLNIGGKRVNL 68
            KVVLLG+G VGK+SL+ R+  NKF+ +   T+   FLTK + + G+   +
Sbjct: 443 LKVVLLGDGGVGKSSLMNRFVSNKFDAQSFHTIGVEFLTKDVVVDGETFTM 291

 Score = 44.3 bits (103), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 18/47 (38%), Positives = 28/47 (59%)
 Frame = -3

Query: 69  AIWDTAGQERFHALGPIYYRDSNGAILVYDVTDEDSFQKVKNWVKEL 115
            IWDTAGQER+ +L   +YR ++  +L + V +  S Q + +W  E 
Sbjct: 150 GIWDTAGQERYKSLRTPFYRGTDCCLLTFSVDNLKSLQSLSDWYDEF 10
>24619
          Length = 509

 Score = 45.1 bits (105), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 28/90 (31%), Positives = 47/90 (52%), Gaps = 3/90 (3%)
 Frame = -2

Query: 76  QERFHALGPIYYRDSNGAILVYDVTDEDSFQKVKNWVKELRKMLGNE---ICLCIVGNKI 132
           QE F A+   Y R  +G +LV+ V D  SF+ + N+  ++ ++   +   + LC   NK+
Sbjct: 508 QEEFSAMREQYMRKGDGFLLVFSVIDYQSFENMVNFHTQILRVKDRDTYPMILC--ANKV 335

Query: 133 DLEKERHVSIQEAESYAESVGAKHYHTSAK 162
           DL  +R VS ++    A  +   +  TSAK
Sbjct: 334 DLVHQRKVSEEQVRDLATRLRIPYIETSAK 245
>34597
          Length = 773

 Score = 43.9 bits (102), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 29/103 (28%), Positives = 50/103 (48%), Gaps = 9/103 (8%)
 Frame = -2

Query: 104 SFQKVKNWVKELRKMLGNEICLCIVGNKIDLEKERHVSIQEAESYAESVGAKHYHTSAKQ 163
           SF+ +  W++ + +    ++   I+GNK D+  +R VS +  E+ A     +   TSAK 
Sbjct: 709 SFENIVKWLRNIDEHANEDVEKMILGNKCDMTDKRVVSKERGEAIAREHSIRFMETSAKS 530

Query: 164 NKGIEELFLDLCKRMI------ETAQVDERA---KGNGSSQAG 197
           N  IE  F +L + ++      E+A+  ER    +GN     G
Sbjct: 529 NINIERAFCELAEAILDKTAGRESAENPERVVIDRGNSDKAPG 401
>10708
          Length = 2775

 Score = 43.5 bits (101), Expect = 6e-05,   Method: Compositional matrix adjust.
 Identities = 16/46 (34%), Positives = 29/46 (63%)
 Frame = -2

Query: 64   KRVNLAIWDTAGQERFHALGPIYYRDSNGAILVYDVTDEDSFQKVK 109
            ++V LA+WDTAGQE +  L P+ Y D++  ++ + +   DS + + 
Sbjct: 2729 QQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIP 2592
>09827
          Length = 1201

 Score = 43.5 bits (101), Expect = 6e-05,   Method: Compositional matrix adjust.
 Identities = 29/120 (24%), Positives = 58/120 (48%), Gaps = 4/120 (3%)
 Frame = -3

Query: 19   KVVLLGEGCVGKTSLVLRYCENKFNDKHITTLQASFLTKKLNIGGKRVNLAIWDTAGQER 78
            +++++G    GKT+++ +    K  +   T     F  + +    K ++  +WD  GQ++
Sbjct: 1109 RILMVGLDAAGKTTILYKL---KLGEIVTTIPTIGFNVETVEY--KNISFTVWDVGGQDK 945

Query: 79   FHALGPIYYRDSNGAILVYDVTDEDSFQKVKNWVKELRKMLG----NEICLCIVGNKIDL 134
               L   Y++++ G I V D  D++  Q+ +   +EL +ML      +  L +  NK DL
Sbjct: 944  IRPLWRHYFQNTQGLIFVVDSNDKERVQEAR---EELTRMLNEDELRDAVLLVFANKQDL 774
>14775
          Length = 380

 Score = 42.0 bits (97), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 26/76 (34%), Positives = 40/76 (52%), Gaps = 3/76 (3%)
 Frame = -2

Query: 30  KTSLVLRYCENKFNDKHITTLQASFLTKKLN---IGGKRVNLAIWDTAGQERFHALGPIY 86
           KT L+ RY +  F D+ + T+  + L  + N        V   +WDT G E + +L   +
Sbjct: 379 KTCLLRRYQKGFFMDRTMPTI--AVLCSEFNESRTDPLNVRYTLWDTGGAETYRSLWVSH 206

Query: 87  YRDSNGAILVYDVTDE 102
           +R +  A+LVYDVT E
Sbjct: 205 FRGAQVALLVYDVTCE 158
>08153
          Length = 1703

 Score = 41.2 bits (95), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 29/127 (22%), Positives = 55/127 (43%), Gaps = 4/127 (3%)
 Frame = +1

Query: 19  KVVLLGEGCVGKTSLVLRYCENKFNDKHITTLQASFLTKKLNIGGKRVNLAIWDTAGQER 78
           +++++G    GKT+++      K     I T   +       +  K ++  +WD  GQ++
Sbjct: 88  RILMVGLDAAGKTTILY-----KLKLGEIVTTIPTIGFNVETVEYKNISFTVWDVGGQDK 252

Query: 79  FHALGPIYYRDSNGAILVYDVTDEDSFQKVKNWVKELRKMLG----NEICLCIVGNKIDL 134
              L   Y++++ G I V D  D +   + K   +EL +ML      +  + +  NK DL
Sbjct: 253 IRPLWRHYFQNTQGLIFVVDSNDRERINEAK---EELARMLNEDDLRDAIILVFANKQDL 423

Query: 135 EKERHVS 141
                 S
Sbjct: 424 PNAYSAS 444
>18509
          Length = 625

 Score = 36.6 bits (83), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 22/71 (30%), Positives = 38/71 (53%)
 Frame = -3

Query: 120 GNEICLCIVGNKIDLEKERHVSIQEAESYAESVGAKHYHTSAKQNKGIEELFLDLCKRMI 179
            +E+ + +VGNK+DL   R+V  ++ +  AE     +  TSAK  +G+++ F  L +   
Sbjct: 536 ADEVPMVLVGNKVDLPI-RNVEQRQGKHMAELYHIPYVETSAKTRQGVDDAFYTLVR--- 369

Query: 180 ETAQVDERAKG 190
           E  +  ER  G
Sbjct: 368 EIRKYKERKDG 336
>33605
          Length = 888

 Score = 36.6 bits (83), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 24/85 (28%), Positives = 43/85 (50%), Gaps = 2/85 (2%)
 Frame = +1

Query: 19  KVVLLGEGCVGKTSLVLRYCENKFNDKHITTLQAS--FLTKKLNIGGKRVNLAIWDTAGQ 76
           ++++LG    GKT+++      KFN + I T+  +  F  K L   G ++N  +WD  GQ
Sbjct: 502 RLLMLGLDNAGKTTIL-----KKFNGEDIDTISPTLGFNIKTLEHRGFKLN--VWDVGGQ 660

Query: 77  ERFHALGPIYYRDSNGAILVYDVTD 101
           +   +    Y+  ++G + V D  D
Sbjct: 661 QSLRSYWRNYFESTDGLVWVVDSAD 735
>10862
          Length = 2896

 Score = 35.8 bits (81), Expect = 0.013,   Method: Compositional matrix adjust.
 Identities = 20/69 (28%), Positives = 33/69 (47%), Gaps = 4/69 (5%)
 Frame = -3

Query: 70   IWDTAGQERFHALGPIYYRDSNGAILVYDVTDEDSFQKVKNWVKELRKMLGN----EICL 125
            +WD  GQ++   L   YY  + G I V D  D D   + +   +EL +++ +    +  +
Sbjct: 2474 VWDVGGQDKIRPLWRHYYTGTQGLIFVVDCADRDRIDEAR---QELHRIINDREMRDAII 2304

Query: 126  CIVGNKIDL 134
             I  NK DL
Sbjct: 2303 LIFANKQDL 2277
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|115648151|ref|NP_062528.2| calcium channel,
voltage-dependent, alpha 1F subunit [Mus musculus]
         (1984 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

32725                                                                 151   2e-36
37279                                                                  75   3e-13
19353                                                                  57   5e-08
03979                                                                  36   0.18 
08217                                                                  36   0.19 
26449                                                                  33   1.3  
>32725
          Length = 572

 Score =  151 bits (382), Expect = 2e-36,   Method: Composition-based stats.
 Identities = 90/189 (47%), Positives = 104/189 (55%)
 Frame = -1

Query: 79  NPIRRSCISIVEWKPFDILILLTIFANCVALGVYIPFPEDDSNTANHNLEQVEYVFLVIF 138
           NPIR  CI IVEWKPF+ LILLTIFANC+AL VY P+P  DSN  N  LE   Y+   I 
Sbjct: 566 NPIRALCIRIVEWKPFEFLILLTIFANCIALAVYTPYPGSDSNVTNQTLEXGTYIPSYIH 387

Query: 139 TVETVLKIVAYGLVLHPSAYIRNGWNLLDFIIVVVGLFSVLLEQGPGRPGDAPHTGGKPG 198
           +     +  +    +       NGWNLLDF IVV+G  S  L        DAP       
Sbjct: 386 S-GMCYEDNSIWFCVT*WCISXNGWNLLDFTIVVMGAISTALSH---FMKDAP------- 240

Query: 199 GFDVKALRAFRVLRPLRLVSGVPSLHIVLNSIMKXXXXXXXXXXXXXXXXXXXXXXXXEL 258
             +VKALRAFRVLRPLRLVSGVPSL +VLNSI+K                        EL
Sbjct: 239 --NVKALRAFRVLRPLRLVSGVPSLQVVLNSILKAMVPLFHIALLVIFVIIIYAIIGLEL 66

Query: 259 FLGRMHKTC 267
           F G++HKTC
Sbjct: 65  FSGKLHKTC 39

 Score = 39.7 bits (91), Expect = 0.012,   Method: Composition-based stats.
 Identities = 43/184 (23%), Positives = 81/184 (44%), Gaps = 9/184 (4%)
 Frame = -1

Query: 1178 PKNPHQYRVWATVNSAAFEYLMFLLILLNTVALAMQHYEQTAPFNYAMDILNMVFTGLFT 1237
            P NP +      V    FE+L+ L I  N +ALA+      +  N     L     G + 
Sbjct: 572  P*NPIRALCIRIVEWKPFEFLILLTIFANCIALAVYTPYPGSDSNVTNQTLEX---GTYI 402

Query: 1238 IEMVLKIIAFKPKHYF---------ADAWNTFDALIVVGSVVDIAVTEVNNGGHLGESSE 1288
               +   + ++    +          + WN  D  IVV   +  A++      H  + + 
Sbjct: 401  PSYIHSGMCYEDNSIWFCVT*WCISXNGWNLLDFTIVVMGAISTALS------HFMKDAP 240

Query: 1289 DSSRISITFFRLFRVMRLVKLLSKGEGIRTLLWTFIKSFQALPYVALLIAMIFFIYAVIG 1348
            +     +   R FRV+R ++L+S    ++ +L + +K+   L ++ALL+  +  IYA+IG
Sbjct: 239  N-----VKALRAFRVLRPLRLVSGVPSLQVVLNSILKAMVPLFHIALLVIFVIIIYAIIG 75

Query: 1349 MQMF 1352
            +++F
Sbjct: 74   LELF 63
>37279
          Length = 371

 Score = 74.7 bits (182), Expect = 3e-13,   Method: Composition-based stats.
 Identities = 41/103 (39%), Positives = 56/103 (54%), Gaps = 7/103 (6%)
 Frame = +1

Query: 687 THTKRSTFDTFPQALLTVFQILTGEDWNVVMYDGIMAYGGPFFPGMLVCVYFIILFICGN 746
           T   R  FDT   A++TVFQ+LT EDWN V+Y+G M Y  P+       +YFI L   GN
Sbjct: 4   TECDRKNFDTLLWAIVTVFQVLTQEDWNTVLYNG-MYYTSPW-----ASLYFIALMTFGN 165

Query: 747 YILLNVFLAIAVDNLASGD-------AGTAKDKGREKSSEGNP 782
           Y+L N+ +AI V+  ++ D        G  +D G  +  EG P
Sbjct: 166 YVLFNLLVAILVEGFSTEDEDKRRKTEGAGRD-GERREGEGTP 291

 Score = 64.7 bits (156), Expect = 3e-10,   Method: Composition-based stats.
 Identities = 36/97 (37%), Positives = 54/97 (55%), Gaps = 6/97 (6%)
 Frame = +1

Query: 312 NFDNFFFAMLTVFQCITMEGWTDVLYWMQDAMGYELPW--VYFVSLVIFGSFFVLNLVLG 369
           NFD   +A++TVFQ +T E W  VLY   + M Y  PW  +YF++L+ FG++ + NL++ 
Sbjct: 22  NFDTLLWAIVTVFQVLTQEDWNTVLY---NGMYYTSPWASLYFIALMTFGNYVLFNLLVA 192

Query: 370 VLSGEFSKE----REKAKARGDFQKLREKQQMEEDLR 402
           +L   FS E    R K +  G   + RE +   E  R
Sbjct: 193 ILVEGFSTEDEDKRRKTEGAGRDGERREGEGTPETGR 303
>19353
          Length = 443

 Score = 57.4 bits (137), Expect = 5e-08,   Method: Compositional matrix adjust.
 Identities = 30/99 (30%), Positives = 56/99 (56%)
 Frame = -1

Query: 303 WPGPNGGITNFDNFFFAMLTVFQCITMEGWTDVLYWMQDAMGYELPWVYFVSLVIFGSFF 362
           W  PN   T+FDNFF+A+L  F+ +T + W    + +  A G     +YF  +++ GSF+
Sbjct: 389 WSNPNFDYTSFDNFFWALLCAFRLMTQDFWEGFYHLILRAEGSAHA-LYFGLVILLGSFY 213

Query: 363 VLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQMEEDL 401
           ++NL+L +++  + + +++  A  + +    KQQ  E L
Sbjct: 212 LVNLILAIVAMSYDETQKQDAADAEEEAAERKQQDAEKL 96

 Score = 35.0 bits (79), Expect = 0.30,   Method: Compositional matrix adjust.
 Identities = 23/74 (31%), Positives = 38/74 (51%)
 Frame = -1

Query: 683 NFDQTHTKRSTFDTFPQALLTVFQILTGEDWNVVMYDGIMAYGGPFFPGMLVCVYFIILF 742
           NFD T     +FD F  ALL  F+++T + W    +  + A G          +YF ++ 
Sbjct: 377 NFDYT-----SFDNFFWALLCAFRLMTQDFWEGFYHLILRAEGSAH------ALYFGLVI 231

Query: 743 ICGNYILLNVFLAI 756
           + G++ L+N+ LAI
Sbjct: 230 LLGSFYLVNLILAI 189
>03979
          Length = 1066

 Score = 35.8 bits (81), Expect = 0.18,   Method: Composition-based stats.
 Identities = 18/76 (23%), Positives = 34/76 (44%), Gaps = 12/76 (15%)
 Frame = +3

Query: 1746 GTQGQDNQNEEQEVPDWTPDLDEQAGTPSNPVLLPPHWSQQ-------HVNGHHVPRRRL 1798
            GT+G+D   +++    W   L+++   P  P  +P + S++       H+    + R+  
Sbjct: 210  GTEGEDEPRKKKRKSRWNAGLEDKTVIPGMPTTIPANLSKEQEKQYIVHLQIEEITRKLR 389

Query: 1799 -----LPPTPAGRKPS 1809
                 +PP P  R PS
Sbjct: 390  SGDLGIPPNPEDRSPS 437
>08217
          Length = 678

 Score = 35.8 bits (81), Expect = 0.19,   Method: Composition-based stats.
 Identities = 22/89 (24%), Positives = 37/89 (41%), Gaps = 6/89 (6%)
 Frame = +1

Query: 2   SESEVGKDTTPEPSPANGTGPGPEWGLCPGP------PTVGTDTSGASGLGTPRRRTQHN 55
           +  E     T +P P+     GP     PGP      P   +D +  + + TP R +   
Sbjct: 109 TSRESSTSRTTKPGPSGRINNGPSRSSMPGPSGCSTQPGQSSDCTPETSVATPGRSSSRL 288

Query: 56  KHKTVAVASAQRSPRALFCLTLTNPIRRS 84
           + K  AV   + S  ++ C +  +PI+ S
Sbjct: 289 RIKKAAVKEIELSASSIQCSSDASPIQCS 375
>26449
          Length = 1657

 Score = 32.7 bits (73), Expect = 1.3,   Method: Composition-based stats.
 Identities = 13/33 (39%), Positives = 18/33 (54%)
 Frame = +1

Query: 1781 PHWSQQHVNGHHVPRRRLLPPTPAGRKPSFTIQ 1813
            P +  QHV+  H P R  +PP P GR+    +Q
Sbjct: 754  PQFLSQHVHS*HQPGREAVPPKPVGRQRGEKLQ 852
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|21313640|ref|NP_082191.1| adaptor-related protein
complex 2, beta 1 subunit isoform b [Mus musculus]
         (937 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

31995                                                                 150   2e-36
19476                                                                 132   8e-31
27755                                                                 122   5e-28
18633                                                                  84   2e-16
31255                                                                  37   0.042
11636                                                                  32   1.3  
22573                                                                  32   1.5  
>31995
          Length = 1263

 Score =  150 bits (380), Expect = 2e-36,   Method: Compositional matrix adjust.
 Identities = 83/237 (35%), Positives = 143/237 (60%), Gaps = 1/237 (0%)
 Frame = -2

Query: 288  LVTLLSGEPEVQYVALRNINLIVQKRPEILKQEIKVFFVKYNDPIYVKLEKLDIMIRLAS 347
            L+ LL    E+QYV L ++  +  KR  + +  +K F+V+ +DP+++KL KL+I+  LA+
Sbjct: 1262 LIRLLRSHQEIQYVVLSDVATMTTKRKGMFEPYLKSFYVRSSDPLHIKLLKLEILTNLAT 1083

Query: 348  QANIAQVLAELKEYATEVDVDFVRKAVRAIGRCAIKVEQSAERCVSTLLDLIQTKVNYVV 407
            + NI+ +L E + Y T  D +F    ++AIGRCA  + +  + C++ L+ L+  +   VV
Sbjct: 1082 ETNISTILREFQTYVTSSDKEFAAATIQAIGRCASSICEVTDTCLNGLVHLMSNRBEAVV 903

Query: 408  QEAIVVIRDIFRKYPNKYESIIATLCENLDSLDEPDARAAMIWIVGEYAERIDN-ADELL 466
             E++VVI+ + +  PN+++ II  +   +D +  P ARA+++W++GEY+ER+   A ++L
Sbjct: 902  AESVVVIKKLLQMRPNEHKGIICHMARMVDKITVPMARASILWLIGEYSERVPKIAPDVL 723

Query: 467  ESFLEGFHDESTQVQLTLLTAIVKLFLKKPSETQELVQQVLSLATQDSDNPDLRDRG 523
                + F  E   V+L +L    KL +  P +T+ L Q VL+LA  D  N D+RDR 
Sbjct: 722  RKLAKSFTSEEDIVKLQVLNLATKLCITNPKQTKLLCQYVLNLAKYD-QNYDIRDRS 555
>19476
          Length = 428

 Score =  132 bits (331), Expect = 8e-31,   Method: Compositional matrix adjust.
 Identities = 59/104 (56%), Positives = 79/104 (75%)
 Frame = +1

Query: 834 RQVFLATWKDIPNENELQFQIKECHLNADTVSSKLQNNNVYTIAKRNVEGQDMLYQSLKL 893
           ++VFL TWK+IP  NELQ+ +       D ++SK+  NN++TIAKRNVEGQDMLYQSLKL
Sbjct: 1   KRVFLNTWKEIPAANELQYSLSGVIGTTDGIASKMTTNNIFTIAKRNVEGQDMLYQSLKL 180

Query: 894 TNGIWILAELRIQPGNPNYTLSLKCRAPEVSQYIYQVYDSILKN 937
           TN IW+L EL++QPGNP  TLSLK R+ EV+  I+  Y+ I+++
Sbjct: 181 TNNIWVLLELKLQPGNPEATLSLKSRSVEVAYIIFAAYEIIIRS 312
>27755
          Length = 510

 Score =  122 bits (307), Expect = 5e-28,   Method: Compositional matrix adjust.
 Identities = 63/115 (54%), Positives = 80/115 (69%)
 Frame = -2

Query: 683 PAVVSSGLNDLFELSTGIGMAPGGYVAPKAVWLPAVKAKGLEISGTFTHRQGHIYMEMNF 742
           P   +S L D+F LS G  ++ G  + PK +WLPA K KGLEI GTF+ R G IYM+M  
Sbjct: 338 PGGATSLLGDIFGLS-GTSLSVGVQI-PKVIWLPAEKGKGLEILGTFSRRNGEIYMDMTL 165

Query: 743 TNKALQHMTDFAIQFNKNSFGVIPSTPLAIHTPLMPNQSIDVSLPLNTLGPVMKM 797
           TNKA+Q  T+FAIQ NKNSFG++P++PL    PL PNQ+ID SL L T GP+ +M
Sbjct: 164 TNKAMQPXTNFAIQLNKNSFGLVPASPLQ-APPLPPNQTIDDSLALGTTGPIQRM 3
>18633
          Length = 404

 Score = 84.3 bits (207), Expect = 2e-16,   Method: Compositional matrix adjust.
 Identities = 38/46 (82%), Positives = 43/46 (93%)
 Frame = +2

Query: 48  SSLFPDVVNCMQTDNLELKKLVYLYLMNYAKSQPDMAIMAVNSFVK 93
           S+LF DVVNCMQT+NLELKKLVYLYLMNYAKSQ D AI++VN+FVK
Sbjct: 161 SALFTDVVNCMQTENLELKKLVYLYLMNYAKSQSDTAIISVNTFVK 298
>31255
          Length = 401

 Score = 37.0 bits (84), Expect = 0.042,   Method: Composition-based stats.
 Identities = 19/85 (22%), Positives = 46/85 (54%)
 Frame = +2

Query: 389 ERCVSTLLDLIQTKVNYVVQEAIVVIRDIFRKYPNKYESIIATLCENLDSLDEPDARAAM 448
           E   + L++L+ T   +V+   + V++ +  K    +  +I  +C++  S+ +  A+AAM
Sbjct: 89  EASEAKLVNLMDTTSLHVLSNLVCVVQSMNIKDDRFWXKLIRPICQHFQSVTDHQAKAAM 268

Query: 449 IWIVGEYAERIDNADELLESFLEGF 473
           ++I+G++     +   +LE  ++ F
Sbjct: 269 LFIIGQHLTHSTDTFSILEECVDNF 343
>11636
          Length = 819

 Score = 32.0 bits (71), Expect = 1.3,   Method: Composition-based stats.
 Identities = 36/151 (23%), Positives = 66/151 (43%), Gaps = 11/151 (7%)
 Frame = +1

Query: 305 NINLIVQKRPEILKQEIKVFFV------KYNDPIYVKLEKLDIMIRLASQANIAQVLAEL 358
           ++N ++  R  + KQ   + +V      K+ D   +KLE     +R A++ N   +  E+
Sbjct: 355 SLNKMLDTRSSVSKQVTLLHYVVETLEKKFAD--VMKLEDDLPHVREAAKVNFKDLEKEI 528

Query: 359 KEY-----ATEVDVDFVRKAVRAIGRCAIKVEQSAERCVSTLLDLIQTKVNYVVQEAIVV 413
                     E +VDF +           K++   +R V+ + D   T  +Y   E    
Sbjct: 529 XALKKGLQGIEKEVDFFKS----------KLDNPHDRFVNVMQDFC-TVASYSFAE---- 663

Query: 414 IRDIFRKYPNKYESIIATLCENLDSLDEPDA 444
           + D F +  NKY+S++   CE+   + +PDA
Sbjct: 664 VEDAFTEMRNKYDSVLKAFCEDSKQV-QPDA 753
>22573
          Length = 755

 Score = 31.6 bits (70), Expect = 1.5,   Method: Composition-based stats.
 Identities = 15/49 (30%), Positives = 23/49 (46%)
 Frame = -2

Query: 549 SEETDLIEPTLLDELICHIGSLASVYHKPPNAFVEGSHGIHRKHLPIHH 597
           +  +D + PTL D  IC +G   S+++ P   F    H    KH  + H
Sbjct: 652 ARRSDFVGPTLTDFFICPVGQAGSIFYLPDTLF----HLPKLKHTNLQH 518
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|21312776|ref|NP_080664.1| synaptic vesicle associated
protein of 30 kD [Mus musculus]
         (266 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

20098                                                                 148   3e-36
31856                                                                  31   0.54 
>20098
          Length = 1020

 Score =  148 bits (373), Expect = 3e-36,   Method: Compositional matrix adjust.
 Identities = 74/215 (34%), Positives = 126/215 (58%), Gaps = 3/215 (1%)
 Frame = -2

Query: 55  KEYFVFRPGTIEQAVEEIRAVVRPVEDGEIQGVWLLTEVDHWNNEKERLVLVTDQSLLIC 114
           K +F ++    + AV+++  +++P  DGE+ G WLLTE+DHW+ E+E++VL+T  S+   
Sbjct: 758 KTFFSYKDTAFQTAVDKVSTIIKPELDGELLGAWLLTEIDHWDMEREKIVLLTANSMFTV 579

Query: 115 KYDFISLQCQQVVRVALSAVDTISCGEFQFPPKS-LNKREGFGVRIQWDKQSRPSFINRW 173
           KY+FI+   Q+  RV L  +  I  G+F++P  S +  R+  G++I W++    SF  +W
Sbjct: 578 KYNFITHTMQEYRRVMLHIIGAIYVGDFKYPENSIMTDRQHGGIQIGWNQGVELSFGQKW 399

Query: 174 NPWSTNMPYATFIEHPM--AGMDEKTASLCHLESFKALLIQAVKKAQKESPLPGQANTVL 231
           NPW T++P+ T   HP+     + +TA+    E +++LL  A K  + + P       V 
Sbjct: 398 NPWCTDIPWLTLAHHPLLYHPKENETATFNVDEFYESLLQAATKVFEVKRP----NEKVK 231

Query: 232 VLERPLLIETYVGLMSFINNEAKLGYSMTRGKIGF 266
           V+E P+ IE+YV L S + N++ LG+   R  + F
Sbjct: 230 VIEGPIQIESYVSLPSMVFNQSGLGFFRDRNGVCF 126
>31856
          Length = 790

 Score = 30.8 bits (68), Expect = 0.54,   Method: Compositional matrix adjust.
 Identities = 15/37 (40%), Positives = 23/37 (62%)
 Frame = -3

Query: 230 VLVLERPLLIETYVGLMSFINNEAKLGYSMTRGKIGF 266
           V V+E P+ IE+YV L S + N++ LG+   R  + F
Sbjct: 728 VKVIEGPIQIESYVSLPSMVFNQSGLGFFRDRNGVCF 618
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|83921589|ref|NP_035944.2| fragile X mental
retardation-related protein 2 [Mus musculus]
         (674 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

19295                                                                 149   3e-36
26269                                                                  39   0.009
09541                                                                  34   0.20 
20748                                                                  32   0.56 
18876                                                                  32   0.90 
32342                                                                  29   4.9  
>19295
          Length = 419

 Score =  149 bits (377), Expect = 3e-36,   Method: Composition-based stats.
 Identities = 77/140 (55%), Positives = 99/140 (70%), Gaps = 1/140 (0%)
 Frame = +3

Query: 154 ENVHKEFKKALGANCIF-LNITNSELFILSTTEAPVKRASLLGDMHFRSLRTKLLLMSRN 212
           E    E KK LG   +   N  ++ + +L+T+ A  KRAS++GDM  R++R KLLL  R 
Sbjct: 3   EGALSELKKHLGGGAMVSYNTADNSIHVLATSTAVTKRASMIGDMFLRNVRQKLLLKMRT 182

Query: 213 EEATKHLETSKQLAAAFQEEFTVREDLMGLAIGTHGANIQQARKVPGVTAIELGEETCTF 272
           EEA K L+++K + + + EEF VREDLMGLAIGTHGANIQQARK+  +T IEL E TCTF
Sbjct: 183 EEAVKKLQSTK-IRSGYMEEFAVREDLMGLAIGTHGANIQQARKIEHITGIELDESTCTF 359

Query: 273 RIYGETPEACRQARSYLEFS 292
           ++YGET EA +QAR  LEFS
Sbjct: 360 KVYGETTEAVKQARGMLEFS 419
>26269
          Length = 679

 Score = 38.5 bits (88), Expect = 0.009,   Method: Compositional matrix adjust.
 Identities = 37/156 (23%), Positives = 65/156 (41%), Gaps = 29/156 (18%)
 Frame = -3

Query: 240 MGLAIGTHGANIQQARKVPGVTAIELGEETCT------FRIYGETPEACRQARSYLEFSE 293
           +GL IG  G  I+Q ++  GV  + + +           RI G+ P+  R     +E  +
Sbjct: 635 VGLIIGKGGETIRQLQERAGVKMVMIQDSNAPSAADKPLRISGDAPKCQRAKEMVIELLQ 456

Query: 294 DS-----------------------VQVPRNLVGKVIGKNGKVIQEIVDKSGVVRVRVEG 330
           +                        + VPR  VG VIGK G++I++I     +V+V+ + 
Sbjct: 455 EKADVPAPGFNNFDNMGPGGPGGIEIPVPRQAVGLVIGKGGEMIKKI-QAEMMVKVQFKP 279

Query: 331 DNDKKNPREEGMVPFIFVGTRENISNAQALLEYHLS 366
           D+ + + R       +  G  E + NA  ++   LS
Sbjct: 278 DDGQADERI-----CLVTGHPEKVQNAVGMIHDLLS 186
>09541
          Length = 2010

 Score = 33.9 bits (76), Expect = 0.20,   Method: Compositional matrix adjust.
 Identities = 22/71 (30%), Positives = 42/71 (59%)
 Frame = -1

Query: 296 VQVPRNLVGKVIGKNGKVIQEIVDKSGVVRVRVEGDNDKKNPREEGMVPFIFVGTRENIS 355
           + VPR  VG VIGK G++I++I ++SG  +V+ + D+ +   R  G+      G+ + + 
Sbjct: 234 IPVPRQAVGLVIGKGGEMIKKIQNESG-AKVQFKPDDGQSEDRLCGV-----TGSPDKVQ 73

Query: 356 NAQALLEYHLS 366
           NA +++   L+
Sbjct: 72  NAISMIHELLA 40
>20748
          Length = 847

 Score = 32.3 bits (72), Expect = 0.56,   Method: Compositional matrix adjust.
 Identities = 13/26 (50%), Positives = 18/26 (69%)
 Frame = -2

Query: 296 VQVPRNLVGKVIGKNGKVIQEIVDKS 321
           +  P NL G++IGK G VI+  +DKS
Sbjct: 654 ILCPNNLCGRIIGKKGIVIKGFMDKS 577
>18876
          Length = 587

 Score = 32.0 bits (71), Expect = 0.90,   Method: Composition-based stats.
 Identities = 38/167 (22%), Positives = 66/167 (39%), Gaps = 32/167 (19%)
 Frame = +2

Query: 232 EFTVREDLMGLAIGTHGANIQQARKVPGVTAIELGEETCT------FRIYGETPEACRQA 285
           E ++    +GL IG  G  I+Q ++  GV  + + +           RI G+ P+  R  
Sbjct: 77  EMSIPGPKVGLIIGKGGETIRQLQERAGVKMVMIQDSNAPSAADKPLRISGDAPKCQRAK 256

Query: 286 RSYLEFSED--------------------------SVQVPRNLVGKVIGKNGKVIQEIVD 319
              +E  ++                           + VPR  VG VIGK G+  Q+I  
Sbjct: 257 EMVIELLQEKADVPAPGFNNFDNMGPGGPGGPGGIEIPVPRQAVGLVIGKGGEHDQKI-Q 433

Query: 320 KSGVVRVRVEGDNDKKNPREEGMVPFIFVGTRENISNAQALLEYHLS 366
              +V+V+ + D+ + + R       +  G  E + NA  ++   LS
Sbjct: 434 AEMMVKVQFKPDDGQADER-----ICLVTGHPEKVQNAVGMIHDLLS 559
>32342
          Length = 661

 Score = 29.3 bits (64), Expect = 4.9,   Method: Compositional matrix adjust.
 Identities = 25/79 (31%), Positives = 39/79 (49%), Gaps = 14/79 (17%)
 Frame = -1

Query: 296 VQVPRNLVGKVIGKNGKVIQEIVDKSGVVRVRV---EGDNDKKNPREEGMVPFIFVG--- 349
           V VP+  +G++IGK G+ ++E+   SG + V+V   +GD D+        VP    G   
Sbjct: 601 VVVPKESIGRIIGKGGQNVKEMQRVSGAI-VQVPEDQGDQDE--------VPVAITGHFY 449

Query: 350 --------TRENISNAQAL 360
                   TR  ++NAQ L
Sbjct: 448 GCQSAQRRTRSLMNNAQGL 392
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|19263326|ref|NP_083012.1| glutamate receptor
interacting protein 1 isoform 1 [Mus musculus]
         (1127 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

26154                                                                 143   4e-36
20073                                                                  55   2e-07
03499                                                                  45   2e-04
29705                                                                  44   4e-04
08480                                                                  42   0.001
03831                                                                  39   0.011
38751                                                                  39   0.013
39267                                                                  34   0.36 
01502                                                                  32   1.2  
02951                                                                  32   1.5  
>26154
          Length = 446

 Score =  143 bits (361), Expect(2) = 4e-36,   Method: Compositional matrix adjust.
 Identities = 67/127 (52%), Positives = 100/127 (78%)
 Frame = -3

Query: 605 KKGSVAHRTGTLELGDKLLAIDNIRLDNCSMEDAVQILQQCEDLVKLKIRKDEDNSDEQE 664
           K+GS AHR G+++ GDKL+AI+++RLD C+++DA  +L+  ++LVKLK+++D+ +   ++
Sbjct: 414 KRGS-AHRCGSIQAGDKLMAINDVRLDTCTVDDATHLLELPDELVKLKVQRDDPDEGNED 238

Query: 665 SSGAIIYTVELKRYGGPLGITISGTEEPFDPIIISSLTKGGLAERTGAIHIGDRILAINS 724
               + YTV+L R+GGPLGITISGTE+P D I+IS LT GGLA++TGA+H+GDR+L IN 
Sbjct: 237 ---CVTYTVQLYRHGGPLGITISGTEDPLDNIVISELTAGGLAQKTGAMHVGDRLLGINE 67

Query: 725 SSLKGKP 731
           S+ K  P
Sbjct: 66  STTKTSP 46

 Score = 27.7 bits (60), Expect(2) = 4e-36,   Method: Compositional matrix adjust.
 Identities = 12/19 (63%), Positives = 15/19 (78%)
 Frame = -2

Query: 728 KGKPLSEAIHLLQMAGETV 746
           + KPLSEAI +LQ AG+ V
Sbjct: 58  QNKPLSEAIRMLQSAGDIV 2

 Score = 66.2 bits (160), Expect = 6e-11,   Method: Compositional matrix adjust.
 Identities = 42/116 (36%), Positives = 66/116 (56%)
 Frame = -3

Query: 511 AERCGVLQIGDRVMAINGIPTEDSTFEEANQLLRDSSITSKVTLEIEFDVAESVIPSSGT 570
           A RCG +Q GD++MAIN +  +  T ++A  LL        V L+++ D  +       T
Sbjct: 402 AHRCGSIQAGDKLMAINDVRLDTCTVDDATHLLELPD--ELVKLKVQRDDPDEGNEDCVT 229

Query: 571 FHVKLPKKHSVELGITISSPSSRKPGDPLVISDIKKGSVAHRTGTLELGDKLLAID 626
           + V+L  +H   LGITIS   +  P D +VIS++  G +A +TG + +GD+LL I+
Sbjct: 228 YTVQL-YRHGGPLGITIS--GTEDPLDNIVISELTAGGLAQKTGAMHVGDRLLGIN 70

 Score = 43.5 bits (101), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 28/84 (33%), Positives = 42/84 (50%), Gaps = 5/84 (5%)
 Frame = -3

Query: 703 KGGLAERTGAIHIGDRILAINSSSLKGKPLSEAIHLLQMAGETVTLKIKKQTDAQSASSP 762
           K G A R G+I  GD+++AIN   L    + +A HLL++  E V LK+++    +     
Sbjct: 414 KRGSAHRCGSIQAGDKLMAINDVRLDTCTVDDATHLLELPDELVKLKVQRDDPDEGNEDC 235

Query: 763 KKFPIP--GHSGDLG---DGEEDP 781
             + +    H G LG    G EDP
Sbjct: 234 VTYTVQLYRHGGPLGITISGTEDP 163

 Score = 39.7 bits (91), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 32/126 (25%), Positives = 59/126 (46%), Gaps = 9/126 (7%)
 Frame = -3

Query: 189 GPADREGTIKPGDRLLSVDGIRLLGTTHAEAMSILKQCGQEATLLIEYD---------VS 239
           G A R G+I+ GD+L++++ +RL   T  +A  +L+   +   L ++ D         V+
Sbjct: 408 GSAHRCGSIQAGDKLMAINDVRLDTCTVDDATHLLELPDELVKLKVQRDDPDEGNEDCVT 229

Query: 240 VMDSVATASGPLLVEVAKTPGASLGVALTTSVCCNKQVIVIDKIKSASIADRCGALHVGD 299
               +    GPL + ++ T                   IVI ++ +  +A + GA+HVGD
Sbjct: 228 YTVQLYRHGGPLGITISGTEDP-------------LDNIVISELTAGGLAQKTGAMHVGD 88

Query: 300 HILSID 305
            +L I+
Sbjct: 87  RLLGIN 70

 Score = 37.0 bits (84), Expect = 0.048,   Method: Compositional matrix adjust.
 Identities = 15/44 (34%), Positives = 28/44 (63%)
 Frame = -3

Query: 289 ADRCGALHVGDHILSIDGTSMEYCTLAEATQFLANTTDQVKLEI 332
           A RCG++  GD +++I+   ++ CT+ +AT  L    + VKL++
Sbjct: 402 AHRCGSIQAGDKLMAINDVRLDTCTVDDATHLLELPDELVKLKV 271

 Score = 31.2 bits (69), Expect = 2.6,   Method: Compositional matrix adjust.
 Identities = 16/49 (32%), Positives = 27/49 (55%)
 Frame = -3

Query: 57  MKKEGTTLGLTVSGGIDKDGKPRVSNLRQGGIAARSDQLDVGDYIKAVN 105
           + + G  LG+T+SG  D      +S L  GG+A ++  + VGD +  +N
Sbjct: 216 LYRHGGPLGITISGTEDPLDNIVISELTAGGLAQKTGAMHVGDRLLGIN 70
>20073
          Length = 582

 Score = 55.1 bits (131), Expect = 2e-07,   Method: Composition-based stats.
 Identities = 28/83 (33%), Positives = 48/83 (57%)
 Frame = +3

Query: 162 FGFVIRGGAHDDRNKSRPVVITCVRPGGPADREGTIKPGDRLLSVDGIRLLGTTHAEAMS 221
            GF + GG    + +S P+ I+ + PGG ADR   +K GD+LLSV+G+ + G  H +A+ 
Sbjct: 6   LGFNVMGG----KEQSSPIYISRIIPGGVADRLNCLKRGDQLLSVNGVSVEGEYHEKAVE 173

Query: 222 ILKQCGQEATLLIEYDVSVMDSV 244
           +LK       L++ Y   +++ +
Sbjct: 174 LLKLAQGSVRLVVRYTPQILEEM 242

 Score = 50.1 bits (118), Expect = 5e-06,   Method: Composition-based stats.
 Identities = 24/70 (34%), Positives = 44/70 (62%)
 Frame = +3

Query: 682 LGITISGTEEPFDPIIISSLTKGGLAERTGAIHIGDRILAINSSSLKGKPLSEAIHLLQM 741
           LG  + G +E   PI IS +  GG+A+R   +  GD++L++N  S++G+   +A+ LL++
Sbjct: 6   LGFNVMGGKEQSSPIYISRIIPGGVADRLNCLKRGDQLLSVNGVSVEGEYHEKAVELLKL 185

Query: 742 AGETVTLKIK 751
           A  +V L ++
Sbjct: 186 AQGSVRLVVR 215

 Score = 38.5 bits (88), Expect = 0.014,   Method: Composition-based stats.
 Identities = 20/59 (33%), Positives = 34/59 (57%)
 Frame = +3

Query: 64  LGLTVSGGIDKDGKPRVSNLRQGGIAARSDQLDVGDYIKAVNGINLAKFRHDEIISLLK 122
           LG  V GG ++     +S +  GG+A R + L  GD + +VNG+++    H++ + LLK
Sbjct: 6   LGFNVMGGKEQSSPIYISRIIPGGVADRLNCLKRGDQLLSVNGVSVEGEYHEKAVELLK 182

 Score = 35.4 bits (80), Expect = 0.13,   Method: Composition-based stats.
 Identities = 19/56 (33%), Positives = 32/56 (57%)
 Frame = +3

Query: 489 SVFATETLSSPPLISYIEADSPAERCGVLQIGDRVMAINGIPTEDSTFEEANQLLR 544
           +V   +  SSP  IS I     A+R   L+ GD+++++NG+  E    E+A +LL+
Sbjct: 15  NVMGGKEQSSPIYISRIIPGGVADRLNCLKRGDQLLSVNGVSVEGEYHEKAVELLK 182
>03499
          Length = 1247

 Score = 45.1 bits (105), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 28/85 (32%), Positives = 43/85 (50%)
 Frame = -3

Query: 151 VEVTLHKEGNTFGFVIRGGAHDDRNKSRPVVITCVRPGGPADREGTIKPGDRLLSVDGIR 210
           V+ +L K    FGF I G  H D   +  + I  V P GPA   G +K GD ++ V+   
Sbjct: 978 VKTSLVKSVRGFGFTIVGSDHPD---TEFLQIKNVVPNGPAYLNGKLKTGDVIVFVNTTC 808

Query: 211 LLGTTHAEAMSILKQCGQEATLLIE 235
           +LG TH + +S+ +      T+ +E
Sbjct: 807 VLGYTHQDVVSLFQTISPGETVTLE 733
>29705
          Length = 674

 Score = 43.9 bits (102), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 23/59 (38%), Positives = 35/59 (59%)
 Frame = -1

Query: 696 IIISSLTKGGLAERTGAIHIGDRILAINSSSLKGKPLSEAIHLLQMAGETVTLKIKKQT 754
           I I+ + +GG AE+ G I + DR+LA+N  +L+     EA+  L+  G+ V L I K T
Sbjct: 359 IFITKVIEGGSAEQDGRIAVMDRLLAVNEHNLEDVTHEEAVAALKSTGDVVRLTIAKPT 183

 Score = 40.0 bits (92), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 24/63 (38%), Positives = 33/63 (52%)
 Frame = -1

Query: 180 VVITCVRPGGPADREGTIKPGDRLLSVDGIRLLGTTHAEAMSILKQCGQEATLLIEYDVS 239
           + IT V  GG A+++G I   DRLL+V+   L   TH EA++ LK  G    L I     
Sbjct: 359 IFITKVIEGGSAEQDGRIAVMDRLLAVNEHNLEDVTHEEAVAALKSTGDVVRLTIAKPTY 180

Query: 240 VMD 242
           + D
Sbjct: 179 IAD 171

 Score = 29.6 bits (65), Expect = 7.9,   Method: Compositional matrix adjust.
 Identities = 15/44 (34%), Positives = 26/44 (59%)
 Frame = -1

Query: 511 AERCGVLQIGDRVMAINGIPTEDSTFEEANQLLRDSSITSKVTL 554
           AE+ G + + DR++A+N    ED T EEA   L+ +    ++T+
Sbjct: 326 AEQDGRIAVMDRLLAVNEHNLEDVTHEEAVAALKSTGDVVRLTI 195
>08480
          Length = 698

 Score = 42.0 bits (97), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 26/124 (20%), Positives = 52/124 (41%)
 Frame = -1

Query: 189 GPADREGTIKPGDRLLSVDGIRLLGTTHAEAMSILKQCGQEATLLIEYDVSVMDSVATAS 248
           GPAD  G ++ GD++LSV+ + +   TH +A   LK+ G    ++ +Y     +      
Sbjct: 698 GPADLSGDLRRGDKILSVNDVDVERATHEQAAQALKRAGDTVEIIAQYKPEDYNRFEAKI 519

Query: 249 GPLLVEVAKTPGASLGVALTTSVCCNKQVIVIDKIKSASIADRCGALHVGDHILSIDGTS 308
             L  ++      SL      ++   + +   +  K + +  R    H GD +   + + 
Sbjct: 518 QDLREQMMNNSAGSLRTTQKRTMFV-RALFDYEPSKDSGLPSRGLWFHYGDILHVTNASD 342

Query: 309 MEYC 312
            E+ 
Sbjct: 341 DEWW 330

 Score = 32.7 bits (73), Expect = 0.75,   Method: Compositional matrix adjust.
 Identities = 14/43 (32%), Positives = 28/43 (65%)
 Frame = -1

Query: 510 PAERCGVLQIGDRVMAINGIPTEDSTFEEANQLLRDSSITSKV 552
           PA+  G L+ GD+++++N +  E +T E+A Q L+ +  T ++
Sbjct: 695 PADLSGDLRRGDKILSVNDVDVERATHEQAAQALKRAGDTVEI 567

 Score = 30.0 bits (66), Expect = 6.0,   Method: Compositional matrix adjust.
 Identities = 14/44 (31%), Positives = 26/44 (59%)
 Frame = -1

Query: 705 GLAERTGAIHIGDRILAINSSSLKGKPLSEAIHLLQMAGETVTL 748
           G A+ +G +  GD+IL++N   ++     +A   L+ AG+TV +
Sbjct: 698 GPADLSGDLRRGDKILSVNDVDVERATHEQAAQALKRAGDTVEI 567
>03831
          Length = 1143

 Score = 38.9 bits (89), Expect = 0.011,   Method: Compositional matrix adjust.
 Identities = 20/76 (26%), Positives = 39/76 (51%)
 Frame = +3

Query: 1006 LYKDSGMEDFGFSVADGLLEKGVYVKNIRPAGPGDVGGLKPYDRLLQVNHVRTRDFDCCL 1065
            L K +  + +GF++     + G Y+ ++ P  P + GGLK  DR+++VN       +   
Sbjct: 591  LCKWADFDGYGFNLHAEKDKPGQYIGSVDPNSPAETGGLKEGDRIIEVNGENIETTNHTA 770

Query: 1066 VVPLIAESGNKLDLVI 1081
            V+  I   G+K  +++
Sbjct: 771  VIQNIKSRGDKTSMLV 818

 Score = 33.9 bits (76), Expect = 0.35,   Method: Compositional matrix adjust.
 Identities = 17/53 (32%), Positives = 29/53 (54%)
 Frame = +3

Query: 182 ITCVRPGGPADREGTIKPGDRLLSVDGIRLLGTTHAEAMSILKQCGQEATLLI 234
           I  V P  PA+  G +K GDR++ V+G  +  T H   +  +K  G + ++L+
Sbjct: 663 IGSVDPNSPAET-GGLKEGDRIIEVNGENIETTNHTAVIQNIKSRGDKTSMLV 818

 Score = 30.8 bits (68), Expect = 3.0,   Method: Compositional matrix adjust.
 Identities = 17/72 (23%), Positives = 34/72 (47%)
 Frame = +3

Query: 1010 SGMEDFGFSVADGLLEKGVYVKNIRPAGPGDVGGLKPYDRLLQVNHVRTRDFDCCLVVPL 1069
            S    +GF++     + G ++  +    P +  GLK  DR+++VN     + +   VV  
Sbjct: 156  SDFNGYGFNLHAEKGKAGQFIGKVDEGSPAEAAGLKAGDRIVEVNGTNIGNENHQQVVGR 335

Query: 1070 IAESGNKLDLVI 1081
            I   G++  L++
Sbjct: 336  IKAGGDETRLLV 371
>38751
          Length = 329

 Score = 38.9 bits (89), Expect = 0.013,   Method: Composition-based stats.
 Identities = 20/59 (33%), Positives = 35/59 (59%)
 Frame = +3

Query: 166 IRGGAHDDRNKSRPVVITCVRPGGPADREGTIKPGDRLLSVDGIRLLGTTHAEAMSILK 224
           I+GG    +    P+V+  +  G  A+++G +  GDR+L V+G      THAEA++I++
Sbjct: 9   IKGG----KEYGTPIVVYVIEEGCQAEQQG-LNIGDRILDVNGTDFTHLTHAEAVTIMR 170

 Score = 35.4 bits (80), Expect = 0.15,   Method: Composition-based stats.
 Identities = 19/59 (32%), Positives = 35/59 (59%)
 Frame = +3

Query: 684 ITISGTEEPFDPIIISSLTKGGLAERTGAIHIGDRILAINSSSLKGKPLSEAIHLLQMA 742
           + I G +E   PI++  + +G  AE+ G ++IGDRIL +N +       +EA+ +++ A
Sbjct: 3   VGIKGGKEYGTPIVVYVIEEGCQAEQQG-LNIGDRILDVNGTDFTHLTHAEAVTIMRNA 176

 Score = 33.1 bits (74), Expect = 0.62,   Method: Composition-based stats.
 Identities = 15/48 (31%), Positives = 25/48 (52%)
 Frame = +3

Query: 76  GKPRVSNLRQGGIAARSDQLDVGDYIKAVNGINLAKFRHDEIISLLKN 123
           G P V  + + G  A    L++GD I  VNG +     H E +++++N
Sbjct: 30  GTPIVVYVIEEGCQAEQQGLNIGDRILDVNGTDFTHLTHAEAVTIMRN 173

 Score = 31.6 bits (70), Expect = 2.1,   Method: Composition-based stats.
 Identities = 17/49 (34%), Positives = 28/49 (57%)
 Frame = +3

Query: 498 SPPLISYIEADSPAERCGVLQIGDRVMAINGIPTEDSTFEEANQLLRDS 546
           +P ++  IE    AE+ G L IGDR++ +NG      T  EA  ++R++
Sbjct: 33  TPIVVYVIEEGCQAEQQG-LNIGDRILDVNGTDFTHLTHAEAVTIMRNA 176

 Score = 31.2 bits (69), Expect = 2.8,   Method: Composition-based stats.
 Identities = 17/46 (36%), Positives = 27/46 (58%)
 Frame = +3

Query: 278 IVIDKIKSASIADRCGALHVGDHILSIDGTSMEYCTLAEATQFLAN 323
           IV+  I+    A++ G L++GD IL ++GT   + T AEA   + N
Sbjct: 39  IVVYVIEEGCQAEQQG-LNIGDRILDVNGTDFTHLTHAEAVTIMRN 173
>39267
          Length = 456

 Score = 33.9 bits (76), Expect = 0.36,   Method: Compositional matrix adjust.
 Identities = 18/41 (43%), Positives = 23/41 (56%)
 Frame = +1

Query: 682 LGITISGTEEPFDPIIISSLTKGGLAERTGAIHIGDRILAI 722
           LG  ISG     D I +S L   G A  +G IH+GDRI ++
Sbjct: 118 LGFNISGNMR--DGIYVSQLHNRGPASESGKIHVGDRIQSV 234
>01502
          Length = 1949

 Score = 32.3 bits (72), Expect = 1.2,   Method: Composition-based stats.
 Identities = 15/47 (31%), Positives = 29/47 (61%)
 Frame = +1

Query: 502 ISYIEADSPAERCGVLQIGDRVMAINGIPTEDSTFEEANQLLRDSSI 548
           +++I  +SPA RCG LQ+ D+++ +NG      T ++A + +R   +
Sbjct: 43  VTFIYENSPAARCG-LQLHDKILQLNGKDFTVVTHKQAVENIRKKPV 180
>02951
          Length = 1076

 Score = 32.0 bits (71), Expect = 1.5,   Method: Composition-based stats.
 Identities = 15/47 (31%), Positives = 29/47 (61%)
 Frame = +2

Query: 502 ISYIEADSPAERCGVLQIGDRVMAINGIPTEDSTFEEANQLLRDSSI 548
           +++I  +SPA RCG LQ+ D+++ +NG      T ++A + +R   +
Sbjct: 29  VTFIYENSPAARCG-LQLHDKILQLNGKDFTVVTHKQAVENIRKKPV 166
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|7710086|ref|NP_057885.1| RAB10, member RAS oncogene
family [Mus musculus]
         (200 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

34597                                                                 137   4e-36
34468                                                                 141   1e-34
08428                                                                 128   2e-30
33794                                                                 116   6e-27
05468                                                                 115   8e-27
26083                                                                 115   9e-27
33380                                                                 104   6e-25
07465                                                                 107   4e-24
14456                                                                 107   5e-24
33374                                                                 102   1e-22
07580                                                                  99   9e-22
30760                                                                  98   2e-21
01972                                                                  90   2e-21
32723                                                                  98   2e-21
17511                                                                  95   2e-20
01398                                                                  93   7e-20
13901                                                                  90   6e-19
11257                                                                  86   7e-18
12339                                                                  82   1e-16
19006                                                                  80   7e-16
13745                                                                  79   1e-15
35581                                                                  78   3e-15
11728                                                                  75   2e-14
27191                                                                  74   6e-14
13750                                                                  73   6e-14
34359                                                                  60   8e-14
19656                                                                  72   2e-13
26536                                                                  70   7e-13
00858                                                                  67   5e-12
09204                                                                  64   3e-11
01095                                                                  61   2e-10
29380                                                                  55   1e-08
09827                                                                  52   1e-07
31291                                                                  51   3e-07
08153                                                                  50   5e-07
00552                                                                  50   7e-07
33605                                                                  45   1e-05
10862                                                                  45   3e-05
14775                                                                  44   3e-05
14119                                                                  41   4e-04
12443                                                                  40   6e-04
25796                                                                  39   0.002
10708                                                                  38   0.002
25618                                                                  38   0.003
31928                                                                  37   0.005
18184                                                                  27   4.3  
01904                                                                  27   4.8  
31899                                                                  27   5.2  
06048                                                                  26   8.5  
>34597
          Length = 773

 Score =  137 bits (346), Expect(2) = 4e-36,   Method: Compositional matrix adjust.
 Identities = 74/110 (67%), Positives = 82/110 (74%), Gaps = 4/110 (3%)
 Frame = -2

Query: 95  KSFENISKWLRNIDEHANEDVERMLLGNKCDMDDKRVVPKGKGEQIAREHGIRFFETSAK 154
           KSFENI KWLRNIDEHANEDVE+M+LGNKCDM DKRVV K +GE IAREH IRF ETSAK
Sbjct: 712 KSFENIVKWLRNIDEHANEDVEKMILGNKCDMTDKRVVSKERGEAIAREHSIRFMETSAK 533

Query: 155 ANINIEKAFLTLAEDILRKTPVKEP--NSENVDISSGGG--VTGWKSKCC 200
           +NINIE+AF  LAE IL KT  +E   N E V I  G      G+ +KCC
Sbjct: 532 SNINIERAFCELAEAILDKTAGRESAENPERVVIDRGNSDKAPGY-NKCC 386

 Score = 30.0 bits (66), Expect(2) = 4e-36,   Method: Compositional matrix adjust.
 Identities = 13/13 (100%), Positives = 13/13 (100%)
 Frame = -3

Query: 76  TSYYRGAMGIMLV 88
           TSYYRGAMGIMLV
Sbjct: 771 TSYYRGAMGIMLV 733
>34468
          Length = 1502

 Score =  141 bits (356), Expect = 1e-34,   Method: Compositional matrix adjust.
 Identities = 77/199 (38%), Positives = 120/199 (60%), Gaps = 9/199 (4%)
 Frame = +1

Query: 3   KKTYDLLFKLLLIGDSGVGKTCVLFRFSDDAFNTTFISTIGIDFKIKTVELQGKKIKLQI 62
           K+T   +FK+++IGDS VGKTC+ +RF    F     +TIG+DF+ K++++  + +KLQ+
Sbjct: 475 KQTQRRIFKIIVIGDSNVGKTCLTYRFCLGKFPDKTEATIGVDFREKSIQVDSEHLKLQL 654

Query: 63  WDTAGQERFH-TITTSYYRGAMGIMLVYDITNGKSFENISKWLRNIDEH-ANEDVERMLL 120
           WDTAGQERF  ++   YYR    ++ VYD+T   SFEN+  W+   D H   + + R+L+
Sbjct: 655 WDTAGQERFRKSMVQHYYRNVHAVVFVYDMTKMSSFENMPAWIEECDRHNLTKYIPRILV 834

Query: 121 GNKCDMDDKRVVPKGKGEQIAREHGIRFFETSA----KANINIEKAFLTLAEDILRKTPV 176
           GNKCD+ ++  V     ++ A  H +  FETSA    KAN +++  F+T+A  +    P+
Sbjct: 835 GNKCDVVERIAVNTNLAQKFADAHNMPLFETSAKDDEKAN-HVDAIFMTVAHKLKXSKPM 1011

Query: 177 KEPN-SENV--DISSGGGV 192
              + SE V  D+S G  V
Sbjct: 1012MPAHLSEMVPGDVSHGDLV 1068
>08428
          Length = 1109

 Score =  128 bits (321), Expect = 2e-30,   Method: Compositional matrix adjust.
 Identities = 61/170 (35%), Positives = 100/170 (58%)
 Frame = -3

Query: 11   KLLLIGDSGVGKTCVLFRFSDDAFNTTFISTIGIDFKIKTVELQGKKIKLQIWDTAGQER 70
            K+ L+GDSGVGK+ ++ RF   ++  +  STIG  F  K++ + G   + QIWDTAGQE+
Sbjct: 1065 KVCLLGDSGVGKSSIVLRFVTGSYRPSQESTIGASFMSKSLVVDGAGYRFQIWDTAGQEK 886

Query: 71   FHTITTSYYRGAMGIMLVYDITNGKSFENISKWLRNIDEHANEDVERMLLGNKCDMDDKR 130
            F  +   YYRGA   ++VYD+T  ++F+++  W++ +      ++   + GNKCD+++ R
Sbjct: 885  FRALAPMYYRGAAAAVIVYDVTRPRTFKSVKSWIQELRSFGPPNIVLAIAGNKCDLEELR 706

Query: 131  VVPKGKGEQIAREHGIRFFETSAKANINIEKAFLTLAEDILRKTPVKEPN 180
             V +   ++ A      F ETSA   +N+E+ F  LA    R+ P +E N
Sbjct: 705  EVVEKDAQEYASSISAIFGETSAMTAVNVEEMFTELA----RQLPPEEDN 568
>33794
          Length = 779

 Score =  116 bits (291), Expect = 6e-27,   Method: Compositional matrix adjust.
 Identities = 57/130 (43%), Positives = 83/130 (63%)
 Frame = -1

Query: 44  IDFKIKTVELQGKKIKLQIWDTAGQERFHTITTSYYRGAMGIMLVYDITNGKSFENISKW 103
           + +K  T+ L+GK++KLQIWDT+GQ RF TI  SY RGA GI+LVYDITN  SF+ I +W
Sbjct: 692 VAYKTTTILLEGKRVKLQIWDTSGQGRFCTIIRSYSRGAQGIILVYDITNKWSFDGIDRW 513

Query: 104 LRNIDEHANEDVERMLLGNKCDMDDKRVVPKGKGEQIAREHGIRFFETSAKANINIEKAF 163
           L+ ++EHA   + ++L+GN+  +  KR V   + E  A  + +  FE S   + NI ++F
Sbjct: 512 LKEVEEHA-PGIPKVLVGNRLHLAYKRQVAAKQAETYASRNNMSCFEISPLCDFNIRESF 336

Query: 164 LTLAEDILRK 173
             LA   L +
Sbjct: 335 CELARMALHR 306
>05468
          Length = 1558

 Score =  115 bits (289), Expect = 8e-27,   Method: Compositional matrix adjust.
 Identities = 65/172 (37%), Positives = 102/172 (59%), Gaps = 7/172 (4%)
 Frame = -3

Query: 9    LFKLLLIGDSGVGKTCVLFRFSDDAFNTTFISTIGIDFKIKTVELQGKK-IKLQIWDTAG 67
            L+K+L+IG+ G GKT ++ R+    F+  + +TIG+DF +K +       I+LQ+WD AG
Sbjct: 1541 LYKILVIGELGTGKTSIIKRYVHQFFSQHYRATIGVDFALKVLNWDADTLIRLQLWDIAG 1362

Query: 68   QERFHTITTSYYRGAMGIMLVYDITNGKSFENISKWLRNIDEHAN----EDVERMLLGNK 123
            QERF  +T  YY+ A+G  +V+D+T   +F+ ++KW  ++D          V  +LL NK
Sbjct: 1361 QERFGNMTRVYYKEAVGAFVVFDVTRASTFDAVTKWKNDLDSKVQLADGSPVPCVLLANK 1182

Query: 124  CDMDDKRVVPK-GKGEQIAREHG-IRFFETSAKANINIEKAFLTLAEDILRK 173
            CD   + +V    + ++   E G I ++ETSAK NINI++A   L   IL K
Sbjct: 1181 CDQAKEGLVNNTSQMDEFCSEKGFIGWYETSAKENINIDEAARFLVTRILEK 1026
>26083
          Length = 432

 Score =  115 bits (289), Expect = 9e-27,   Method: Compositional matrix adjust.
 Identities = 55/114 (48%), Positives = 78/114 (68%)
 Frame = +1

Query: 10  FKLLLIGDSGVGKTCVLFRFSDDAFNTTFISTIGIDFKIKTVELQGKKIKLQIWDTAGQE 69
           FKL+ +G+  VGKT ++ RF  D+F+ T+ +TIGIDF  KT+ L+ + I+LQ+WDTAGQE
Sbjct: 79  FKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTIRLQLWDTAGQE 258

Query: 70  RFHTITTSYYRGAMGIMLVYDITNGKSFENISKWLRNIDEHANEDVERMLLGNK 123
           RF ++  SY R +   ++VYDITN  SF   SKW+ ++      DV  ML+GNK
Sbjct: 259 RFRSLIPSYIRDSSVAVVVYDITNANSFHQTSKWIDDVRTERGSDVIIMLVGNK 420
>33380
          Length = 282

 Score =  104 bits (259), Expect(2) = 6e-25,   Method: Compositional matrix adjust.
 Identities = 45/82 (54%), Positives = 64/82 (78%)
 Frame = +3

Query: 50  TVELQGKKIKLQIWDTAGQERFHTITTSYYRGAMGIMLVYDITNGKSFENISKWLRNIDE 109
           TV  Q K++KLQIWDTAGQER+ TITT+YYRGAMG +L+YD+TN +SF  +  W   I  
Sbjct: 36  TVFRQDKRVKLQIWDTAGQERYRTITTAYYRGAMGFILMYDVTNEESFNAVQDWCTQIKT 215

Query: 110 HANEDVERMLLGNKCDMDDKRV 131
           ++ ++ + +L+GNKCD++D+RV
Sbjct: 216 YSWDNAQVVLVGNKCDLEDERV 281

 Score = 26.2 bits (56), Expect(2) = 6e-25,   Method: Compositional matrix adjust.
 Identities = 8/15 (53%), Positives = 14/15 (93%)
 Frame = +2

Query: 38 FISTIGIDFKIKTVE 52
          F+ST+GIDFK+ +++
Sbjct: 2  FVSTVGIDFKVNSLQ 46
>07465
          Length = 1103

 Score =  107 bits (266), Expect = 4e-24,   Method: Compositional matrix adjust.
 Identities = 51/151 (33%), Positives = 89/151 (58%)
 Frame = +3

Query: 23  TCVLFRFSDDAFNTTFISTIGIDFKIKTVELQGKKIKLQIWDTAGQERFHTITTSYYRGA 82
           + ++ R+    F   +  TIG+DF  + +E+ G+ ++L +WDTAGQE F  IT +YYRGA
Sbjct: 240 SSMIQRYCKGIFTKDYKKTIGVDFLERQIEVGGEDVRLMLWDTAGQEEFDAITKAYYRGA 419

Query: 83  MGIMLVYDITNGKSFENISKWLRNIDEHANEDVERMLLGNKCDMDDKRVVPKGKGEQIAR 142
              +L +   +  SFE +  W R +++   E +  +++ NK D+ D  VV   + E +A+
Sbjct: 420 QACVLAFSTVDRDSFEALETWKRKVEDEVGE-IGMVIVQNKIDLIDDAVVRPEEAENLAK 596

Query: 143 EHGIRFFETSAKANINIEKAFLTLAEDILRK 173
           +  +RF+ TS K N+N+++ F  LA+  L +
Sbjct: 597 KLRLRFYRTSVKENMNVDEVFRYLADKYLHQ 689
>14456
          Length = 1867

 Score =  107 bits (266), Expect = 5e-24,   Method: Compositional matrix adjust.
 Identities = 63/191 (32%), Positives = 102/191 (53%), Gaps = 9/191 (4%)
 Frame = -1

Query: 19   GVGKTCVLFRFSDDAFNTTFISTIGIDFKIKTVELQGKKIKLQIWDTAGQERFHTITTSY 78
            GVGK+ ++ RF  + F+     TIG++F  K V +  +   +QIWDTAGQERF ++ T +
Sbjct: 1111 GVGKSSLMNRFVSNKFDAQSFHTIGVEFLNKDVVVDDETYTMQIWDTAGQERFKSLRTPF 932

Query: 79   YRGAMGIMLVYDITNGKSFENISKWLRNIDEHANEDVER------MLLGNKCDMDDKRVV 132
            YRGA   +L + + + +SF N+S W +    +A  D++       ++LGNK D++ ++V 
Sbjct: 931  YRGADCCLLTFSVDSMQSFRNLSMWRKEFLYYA--DIQDGVTFPFVVLGNKIDVEGRQVT 758

Query: 133  PKGKGEQIAREHGIRFFETSAKANINIEKAFLTLAE---DILRKTPVKEPNSENVDISSG 189
             +             +FETSAK   N+EKAFL   +   ++  +  VK  +   VD++  
Sbjct: 757  NEEARSWCTANSNAPYFETSAKDATNVEKAFLAAVQRLREVEDQQEVKTAHGNTVDLNRA 578

Query: 190  GGVTGWKSKCC 200
                G  S CC
Sbjct: 577  A--RGKSSSCC 551
>33374
          Length = 489

 Score =  102 bits (253), Expect = 1e-22,   Method: Compositional matrix adjust.
 Identities = 46/114 (40%), Positives = 70/114 (61%)
 Frame = +1

Query: 46  FKIKTVELQGKKIKLQIWDTAGQERFHTITTSYYRGAMGIMLVYDITNGKSFENISKWLR 105
           F  +TV L    +K +IWDTAGQER+H++   YYRGA   ++VYDITN  +F     W++
Sbjct: 139 FLTQTVCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNQDTFGRAKTWVK 318

Query: 106 NIDEHANEDVERMLLGNKCDMDDKRVVPKGKGEQIAREHGIRFFETSAKANINI 159
            +   A+ ++   L GNK D+ +KR+V   + +  A E+ + F ETSAK  +N+
Sbjct: 319 ELQRQASPNIVIALAGNKADLANKRMVEFEEAQAYAEENSLLFMETSAKTAMNV 480

 Score = 35.8 bits (81), Expect = 0.012,   Method: Compositional matrix adjust.
 Identities = 19/52 (36%), Positives = 31/52 (59%)
 Frame = +2

Query: 10 FKLLLIGDSGVGKTCVLFRFSDDAFNTTFISTIGIDFKIKTVELQGKKIKLQ 61
          FKL+L+G+S VGK+ ++ RF    F+    STIG  F ++   L  ++  L+
Sbjct: 32 FKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAF*LRQFVLMTQQSSLR 187
>07580
          Length = 921

 Score = 99.4 bits (246), Expect = 9e-22,   Method: Compositional matrix adjust.
 Identities = 55/157 (35%), Positives = 87/157 (55%), Gaps = 1/157 (0%)
 Frame = +3

Query: 20  VGKTCVLFRFSDDAFNTTFISTIGIDFKIKTVELQGKKIKLQIWDTAGQERFHTITTSYY 79
           + K   L+      F   +  TI   ++ K VE+ G++  L+I DTAG E+F  +   Y 
Sbjct: 93  LAKVL*LYSLCKGIFVEKYDPTIEDSYR-KQVEVDGQQCMLEILDTAGTEQFTAMRDLYM 269

Query: 80  RGAMGIMLVYDITNGKSFENISKWLRNIDEHAN-EDVERMLLGNKCDMDDKRVVPKGKGE 138
           +   G +L Y IT   +F ++ +    I    + +DV  +L+GNKCD++D+RVV K +G+
Sbjct: 270 KNGQGFLLAYSITAQSTFNDLQELREQILRVKDTDDVPMLLVGNKCDLEDERVVGKDQGQ 449

Query: 139 QIAREHGIRFFETSAKANINIEKAFLTLAEDILRKTP 175
            +AR     F ETSAKA IN+ + F+ L   I +K+P
Sbjct: 450 GLARSFSCAFLETSAKARINVNEIFMDLVRQINKKSP 560
>30760
          Length = 596

 Score = 97.8 bits (242), Expect = 2e-21,   Method: Compositional matrix adjust.
 Identities = 53/166 (31%), Positives = 91/166 (54%), Gaps = 5/166 (3%)
 Frame = -1

Query: 8   LLFKLLLIGDSGVGKT--CVLFRFSDDAFNTTFISTIGIDFKIKTVELQGKK--IKLQIW 63
           L  K ++ GDSGVGK+  C +F      F   +  T G++  +K V +   +  ++L ++
Sbjct: 533 LRAKCIVTGDSGVGKSSICQVFHSDSAHFPKNYSMTTGVEVLVKLVNIPDSRDQVELYLF 354

Query: 64  DTAGQERFHTITTSYYRGAMGIMLVYDITNGKSFENISKWLRNI-DEHANEDVERMLLGN 122
           D+AG+E F    T ++     +M+VYD+T+  SF    +WL  +     N  +  +L+ N
Sbjct: 353 DSAGKEIFSENVTKFWDQPSVVMVVYDVTDETSFSGCVRWLERVRAAKPNTVIPGVLVAN 174

Query: 123 KCDMDDKRVVPKGKGEQIAREHGIRFFETSAKANINIEKAFLTLAE 168
           K D+D++R V + +G+ +A+ HG+ +FE SAK   N +  F  LA 
Sbjct: 173 KTDLDERRRVSRKEGKDLAQSHGLEYFECSAKEMQNTDTPFFCLAH 36
>01972
          Length = 2359

 Score = 89.7 bits (221), Expect(2) = 2e-21,   Method: Compositional matrix adjust.
 Identities = 46/151 (30%), Positives = 86/151 (56%)
 Frame = +3

Query: 38  FISTIGIDFKIKTVELQGKKIKLQIWDTAGQERFHTITTSYYRGAMGIMLVYDITNGKSF 97
           +++T+G++           K+K  +WDTAGQE+F  +   YY      ++++D+T+  ++
Sbjct: 387 YVATLGVEVHPLLFHTSRGKLKFNVWDTAGQEKFGGLRDGYYIQGQCAVIMFDVTSRVTY 566

Query: 98  ENISKWLRNIDEHANEDVERMLLGNKCDMDDKRVVPKGKGEQIAREHGIRFFETSAKANI 157
           +N+  W R++     E++  +L GNK D+ D++V  K K     R+  +++++ SAK+N 
Sbjct: 567 KNVPNWHRDL-VRVCENIPIVLCGNKVDIKDRKV--KAKAIVFHRKKNLQYYDISAKSNY 737

Query: 158 NIEKAFLTLAEDILRKTPVKEPNSENVDISS 188
           N EK FL LA  +     V +PN E V++ +
Sbjct: 738 NFEKPFLWLARKL-----VGDPNLEFVEMPA 815

 Score = 28.9 bits (63), Expect(2) = 2e-21,   Method: Compositional matrix adjust.
 Identities = 13/31 (41%), Positives = 17/31 (54%)
 Frame = +1

Query: 10  FKLLLIGDSGVGKTCVLFRFSDDAFNTTFIS 40
           FKL+L+GD GVGKT  + R     F    + 
Sbjct: 304 FKLVLVGDGGVGKTTFVKRHVTGEFEKNMLP 396
>32723
          Length = 384

 Score = 97.8 bits (242), Expect = 2e-21,   Method: Compositional matrix adjust.
 Identities = 45/100 (45%), Positives = 66/100 (66%)
 Frame = +2

Query: 68  QERFHTITTSYYRGAMGIMLVYDITNGKSFENISKWLRNIDEHANEDVERMLLGNKCDMD 127
           QERF +IT SYYR A  ++LVYD+ + +S+E++ +W+  I+ +A   V   L+GNK D  
Sbjct: 2   QERFRSITQSYYRSANALILVYDVCSQQSYESLPQWIHEIELYAGTKVLAFLVGNKIDQT 181

Query: 128 DKRVVPKGKGEQIAREHGIRFFETSAKANINIEKAFLTLA 167
           DKR +P   G++ A  + +RF ETSAK   N+EK F T+A
Sbjct: 182 DKREIPTHIGKEFAERYEMRFLETSAKEADNVEKLFSTIA 301
>17511
          Length = 483

 Score = 95.1 bits (235), Expect = 2e-20,   Method: Compositional matrix adjust.
 Identities = 45/123 (36%), Positives = 77/123 (62%), Gaps = 4/123 (3%)
 Frame = -3

Query: 8   LLFKLLLIGDSGVGKTCVLFRFSDDAFNTTFISTIGIDFKIKTVELQGKKIKLQIWDTAG 67
           +L K++++GDSGVGKT ++ ++ +  F+  + +TIG DF  K V +  + + +QIWDTAG
Sbjct: 370 VLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQIWDTAG 191

Query: 68  QERFHTITTSYYRGAMGIMLVYDITNGKSFENISKW----LRNIDEHANEDVERMLLGNK 123
           QERF ++  ++YRGA   +LV+D+T   +F ++  W    L        E+   +++GNK
Sbjct: 190 QERFQSLGVAFYRGADCCVLVFDVTMPNTFRSLDSWRDEFLIQASPRDPENFPFVVIGNK 11

Query: 124 CDM 126
            D+
Sbjct: 10  IDL 2
>01398
          Length = 1421

 Score = 93.2 bits (230), Expect = 7e-20,   Method: Compositional matrix adjust.
 Identities = 46/103 (44%), Positives = 64/103 (62%), Gaps = 1/103 (0%)
 Frame = -2

Query: 68   QERFHTITTSYYRGAMGIMLVYDITNGKSFENISKWLRNIDEHANEDVERML-LGNKCDM 126
            QERF +IT SYYR ++G+++VYDIT   +FEN+ +W      H        L LG+K D 
Sbjct: 1420 QERFRSITRSYYRNSVGVIIVYDITKRSTFENLKQWYEEARNHIEPHKAIFLVLGHKSDR 1241

Query: 127  DDKRVVPKGKGEQIAREHGIRFFETSAKANINIEKAFLTLAED 169
            +D R V   +G + A  HG++FFETSAK+  NIE  F  +A+D
Sbjct: 1240 EDARQVTAREGRRFAEMHGLKFFETSAKSGHNIEDVFAQIAKD 1112
>13901
          Length = 962

 Score = 90.1 bits (222), Expect = 6e-19,   Method: Compositional matrix adjust.
 Identities = 40/98 (40%), Positives = 66/98 (67%), Gaps = 1/98 (1%)
 Frame = -3

Query: 7   DLLFKLLLIGDSGVGKTCVLFRFSDDAFNTTFISTIGIDFKIKTVELQGK-KIKLQIWDT 65
           ++LFK+++IGD  VGKT  + R+ +D+F   +  TIG+DF +K +    K  IKLQ+WD 
Sbjct: 294 EVLFKVIIIGDPTVGKTSFVQRYVNDSFRRDYKMTIGVDFALKVIRWSDKCNIKLQLWDI 115

Query: 66  AGQERFHTITTSYYRGAMGIMLVYDITNGKSFENISKW 103
           AGQERF ++T  YY+ A   ++++D+T   +++N  +W
Sbjct: 114 AGQERFTSMTRVYYKDAHACIVMFDLTQKNTYQNAIRW 1
>11257
          Length = 1102

 Score = 86.3 bits (212), Expect = 7e-18,   Method: Compositional matrix adjust.
 Identities = 49/157 (31%), Positives = 80/157 (50%), Gaps = 5/157 (3%)
 Frame = -2

Query: 49   KTVELQGKKIKLQIWDTAGQERFHTITTSYYRGAMGIMLVYDITNGKSFENISKWLRNID 108
            K V + G+   +QIWDTAGQER+ ++ T +YRG    +L + + N KS +++S W     
Sbjct: 1053 KDVVVDGETFTMQIWDTAGQERYKSLRTPFYRGTDCCLLTFSVDNLKSLQSLSDWYDEFV 874

Query: 109  EHAN----EDVERMLLGNKCDMDDKRVVPKGKGEQIAREHG-IRFFETSAKANINIEKAF 163
             +A+         +++GNK D+++ R V         R HG + +FETSAK ++N+++AF
Sbjct: 873  NYADIQDSASFPFVIIGNKADIEE-REVSSEDAYNWCRTHGNLPYFETSAKDSLNVQQAF 697

Query: 164  LTLAEDILRKTPVKEPNSENVDISSGGGVTGWKSKCC 200
            L +   +       +      D      V   KS CC
Sbjct: 696  LAVVRRLREMDEQMDERPTRTDTVDLKRVAKVKSSCC 586
>12339
          Length = 578

 Score = 82.0 bits (201), Expect = 1e-16,   Method: Compositional matrix adjust.
 Identities = 42/110 (38%), Positives = 71/110 (64%), Gaps = 4/110 (3%)
 Frame = -2

Query: 68  QERFHTITTSYYRGAMGIMLVYDITNGKSFENISKWLRN-IDEHANEDVER---MLLGNK 123
           QERF ++  ++YRGA   +LVYD+T  K+F+++  W R  +++ +  D E    +++GNK
Sbjct: 577 QERFQSLGVAFYRGADCCILVYDVTEXKTFDSLDSWQREFLNQASPRDPEHFPFVVIGNK 398

Query: 124 CDMDDKRVVPKGKGEQIAREHGIRFFETSAKANINIEKAFLTLAEDILRK 173
            D+D++ V  K      + + GI +FETSAK  IN+E+AF T+A++ L +
Sbjct: 397 IDLDNRVVTAKRGQGWCSTKGGIPYFETSAKEAINVEQAFQTVAKNALAQ 248
>19006
          Length = 568

 Score = 79.7 bits (195), Expect = 7e-16,   Method: Compositional matrix adjust.
 Identities = 46/142 (32%), Positives = 77/142 (54%), Gaps = 5/142 (3%)
 Frame = -2

Query: 11  KLLLIGDSGVGKTCVLFRFSDDAFNTTFISTIGIDFKIKTVELQGKKIKLQIWDTAGQER 70
           KL+++GD   GKTC+L  FS D F   ++ T+  ++ +  +E+  K+++L +WDTAGQE 
Sbjct: 432 KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENY-VADIEVDSKQVELALWDTAGQED 256

Query: 71  FHTITTSYYRGAMGIMLVYDITNGKSFENIS-KWLRNIDEHANEDVERMLLGNKCDM--- 126
           +  +    Y     I++ + I +  S ENI  KW   +  H   +V  +L+GNK D+   
Sbjct: 255 YDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEV-RHFCPNVPIILVGNKKDLRND 79

Query: 127 -DDKRVVPKGKGEQIAREHGIR 147
            + KR + K K E +  +   R
Sbjct: 78  ENTKRELMKMKQEPVRLDRRAR 13
>13745
          Length = 1045

 Score = 78.6 bits (192), Expect = 1e-15,   Method: Compositional matrix adjust.
 Identities = 40/110 (36%), Positives = 65/110 (59%), Gaps = 4/110 (3%)
 Frame = +2

Query: 68  QERFHTITTSYYRGAMGIMLVYDITNGKSFENISKW----LRNIDEHANEDVERMLLGNK 123
           QERF ++  ++YRGA   +LVYD+T   SF+N+  W    L        E    ++LGNK
Sbjct: 2   QERFQSLGVAFYRGADCCVLVYDVTAPNSFKNLDSWRDEFLIQASPRDPEHFPFVVLGNK 181

Query: 124 CDMDDKRVVPKGKGEQIAREHGIRFFETSAKANINIEKAFLTLAEDILRK 173
            D+D+++V  +   +    ++ I ++ETSAK  IN+E AF T+A++ L +
Sbjct: 182 VDLDNRQVSTRRAQQWCQSKNDIPYYETSAKEGINVEMAFQTIAKNALEQ 331
>35581
          Length = 364

 Score = 77.8 bits (190), Expect = 3e-15,   Method: Compositional matrix adjust.
 Identities = 36/84 (42%), Positives = 56/84 (66%), Gaps = 1/84 (1%)
 Frame = +2

Query: 8   LLFKLLLIGDSGVGKTCVLFRFSDDAFNTTFISTIGIDFKIKTVEL-QGKKIKLQIWDTA 66
           L FK +L+GD+GVGKTC+L R + D F  + ++++     + TV L  G    + +WDTA
Sbjct: 41  LYFKCVLLGDAGVGKTCLLNRLATDKFLDSPLTSLTTASLLTTVTLTSGVMASVDLWDTA 220

Query: 67  GQERFHTITTSYYRGAMGIMLVYD 90
           GQER+ ++T+SYYR    +++VYD
Sbjct: 221 GQERYRSLTSSYYRDTKAVLIVYD 292
>11728
          Length = 635

 Score = 75.1 bits (183), Expect = 2e-14,   Method: Compositional matrix adjust.
 Identities = 42/134 (31%), Positives = 72/134 (53%), Gaps = 2/134 (1%)
 Frame = -1

Query: 10  FKLLLIGDSGVGKTCVLFRFSDDAFNTTFISTIGIDFKIKTVELQGKKIKLQIWDTAGQE 69
            K +++GD  VGKTC+L  ++ +AF   +I T+  D     V +  K I L +WDTAGQE
Sbjct: 488 IKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTV-FDNYSANVMVDSKPINLGLWDTAGQE 312

Query: 70  RFHTITTSYYRGAMGIMLVYDITNGKSFENI-SKWLRNIDEHANEDVERMLLGNKCDM-D 127
            +  +    Y      ++ + + +  SFEN+ +KW   +  H   +   +L+G K D+ +
Sbjct: 311 DYDRLRPLSYPQTDVFLICFSLISPASFENVKAKWYPEVSHHC-PNTPIILVGTKLDLRE 135

Query: 128 DKRVVPKGKGEQIA 141
           DK  + K K +++A
Sbjct: 134 DKETIEKLKEKKLA 93
>27191
          Length = 443

 Score = 73.6 bits (179), Expect = 6e-14,   Method: Compositional matrix adjust.
 Identities = 30/102 (29%), Positives = 56/102 (54%)
 Frame = +1

Query: 22  KTCVLFRFSDDAFNTTFISTIGIDFKIKTVELQGKKIKLQIWDTAGQERFHTITTSYYRG 81
           KTC++  F +  FN  +  T+G+D+  K   + G  +++ +WD +G   +  +    Y G
Sbjct: 1   KTCLIKHFCESKFNQGYQPTVGVDYGFKIQTVNGVDMRVHMWDLSGSNEYLDVRNELYTG 180

Query: 82  AMGIMLVYDITNGKSFENISKWLRNIDEHANEDVERMLLGNK 123
           +  I +V+D++N  SFE +  WLR I+  A      +++GN+
Sbjct: 181 SDAIFIVFDVSNTPSFEALDSWLREINRFATGSPLNVIVGNR 306
>13750
          Length = 503

 Score = 73.2 bits (178), Expect = 6e-14,   Method: Compositional matrix adjust.
 Identities = 42/152 (27%), Positives = 75/152 (49%), Gaps = 1/152 (0%)
 Frame = -2

Query: 22  KTCVLFRFSDDAFNTTFISTIGIDF-KIKTVELQGKKIKLQIWDTAGQERFHTITTSYYR 80
           KTC+L R+    F    + TI +   +          ++  +WDT G E + ++  S++R
Sbjct: 502 KTCLLRRYQKGFFMDRTMPTIAVLCSEFNESRTDPLNVRYTLWDTGGAETYRSLWVSHFR 323

Query: 81  GAMGIMLVYDITNGKSFENISKWLRNIDEHANEDVERMLLGNKCDMDDKRVVPKGKGEQI 140
           GA   +LVYD+T   SF   +   R        + + + +G+K D+++ RV+   +G+  
Sbjct: 322 GAQVALLVYDVTCEWSFLTATTVWRKALMKNIPEAQVIFVGSKTDLEENRVISTERGQAF 143

Query: 141 AREHGIRFFETSAKANINIEKAFLTLAEDILR 172
           A + G  FFETS+    N++  F  +A  + R
Sbjct: 142 ATQCGYTFFETSSVTGKNVDAVFWEIAFILAR 47
>34359
          Length = 1042

 Score = 59.7 bits (143), Expect(2) = 8e-14,   Method: Compositional matrix adjust.
 Identities = 26/98 (26%), Positives = 55/98 (56%)
 Frame = +3

Query: 38  FISTIGIDFKIKTVELQGKKIKLQIWDTAGQERFHTITTSYYRGAMGIMLVYDITNGKSF 97
           +++T+G++            ++  +WDTAGQE+F  +   YY      ++++D+T+  ++
Sbjct: 135 YVATLGVEVHPLQFNTSRGLLRFNVWDTAGQEKFGGLRDGYYIQGTCAIIMFDVTSRVTY 314

Query: 98  ENISKWLRNIDEHANEDVERMLLGNKCDMDDKRVVPKG 135
           +N+  W R++     E++  +L GNK D+ D++V  K 
Sbjct: 315 KNVPNWHRDL-VRVCENIPIVLCGNKVDIKDRKVKAKA 425

 Score = 33.5 bits (75), Expect(2) = 8e-14,   Method: Compositional matrix adjust.
 Identities = 16/51 (31%), Positives = 31/51 (60%)
 Frame = +2

Query: 138 EQIAREHGIRFFETSAKANINIEKAFLTLAEDILRKTPVKEPNSENVDISS 188
            ++++E  +++++ SAK+N N EK FL LA  +     V +PN   V++ +
Sbjct: 425 HRLSQEKNLQYYDISAKSNYNFEKPFLWLARKL-----VGDPNLXFVEMPA 562
>19656
          Length = 428

 Score = 71.6 bits (174), Expect = 2e-13,   Method: Compositional matrix adjust.
 Identities = 34/102 (33%), Positives = 56/102 (54%), Gaps = 1/102 (0%)
 Frame = +3

Query: 11  KLLLIGDSGVGKTCVLFRFSDDAFNTTFISTIGIDFKIKTVELQGKKIKLQIWDTAGQER 70
           K +++GD  VGKTC+L  ++ +AF   +I T+  D     V + G+ + L +WDTAGQE 
Sbjct: 117 KCVVVGDGAVGKTCLLISYTTNAFPGEYIPTV-FDNYSANVMVDGRPVNLGLWDTAGQED 293

Query: 71  FHTITTSYYRGAMGIMLVYDITNGKSFENI-SKWLRNIDEHA 111
           +  +    Y      +L + + +  SFENI +KW   ++ H 
Sbjct: 294 YDRLRPLSYPQTDVFLLCFSVASPASFENIRAKWYPEVNHHC 419
>26536
          Length = 829

 Score = 69.7 bits (169), Expect = 7e-13,   Method: Compositional matrix adjust.
 Identities = 41/138 (29%), Positives = 70/138 (50%), Gaps = 3/138 (2%)
 Frame = +2

Query: 56  KKIKLQIWDTAGQERFHTITTSYYRGAMGIMLVYDITNGKSF---ENISKWLRNIDEHAN 112
           +++     DTAGQE + ++   Y R   G ++VY +T+  SF   E + +WL    +  +
Sbjct: 122 RRVSWTFLDTAGQEEYSSMREHYTRSGDGFIVVYSVTDVTSFQEAEAVFRWLTRFQDETS 301

Query: 113 EDVERMLLGNKCDMDDKRVVPKGKGEQIAREHGIRFFETSAKANINIEKAFLTLAEDILR 172
             +  +L GNK D+   R V   +G ++A   G+ +FETSAK   N+ + +      +LR
Sbjct: 302 --IHAVLCGNKTDLTSDRKVTPEEGRKMADRLGMLYFETSAKTGDNVSQVY----HGLLR 463

Query: 173 KTPVKEPNSENVDISSGG 190
             P    + + V + SGG
Sbjct: 464 SIPRSGTDYKIVMLGSGG 517
>00858
          Length = 1658

 Score = 67.0 bits (162), Expect = 5e-12,   Method: Compositional matrix adjust.
 Identities = 53/162 (32%), Positives = 85/162 (52%), Gaps = 1/162 (0%)
 Frame = -2

Query: 10   FKLLLIGDSGVGKTCVLFRFSDDAFNTTFISTIGIDFKIKTVELQGKKIKLQIWDTAGQE 69
            +KL+++G  GVGK+ +  +   + F   +  T   D   K V + G+   L I DTAGQE
Sbjct: 1588 YKLVVVGAGGVGKSALTIQLXQNHFVEEYDPTXE-DSXRKQVVIDGETCLLDILDTAGQE 1412

Query: 70   RFHTITTSYYRGAMGIMLVYDITNGKSFENISKWLRNIDEHANED-VERMLLGNKCDMDD 128
                +     R   G + V+ + N KSFE+I+++   I    + D V  +L+GNK D+  
Sbjct: 1411 EXSAMRDQCMRTGEGFLCVFAVXNLKSFEDINQYREQIKRVKDADEVPMVLVGNKVDL-P 1235

Query: 129  KRVVPKGKGEQIAREHGIRFFETSAKANINIEKAFLTLAEDI 170
             R V + +G+ +A  + I + ETSAK    ++ AF TL  +I
Sbjct: 1234 IRNVEQRQGKHMAELYHIPYVETSAKTRQGVDDAFYTLVREI 1109
>09204
          Length = 1051

 Score = 64.3 bits (155), Expect = 3e-11,   Method: Compositional matrix adjust.
 Identities = 35/108 (32%), Positives = 61/108 (56%), Gaps = 4/108 (3%)
 Frame = -3

Query: 70   RFHTITTSYYRGAMGIMLVYDITNGKSFENISKWLRNIDEHANEDVERMLLGNKCDM--D 127
            R+  ++  YYRGA   +L +D+T+  SF+ I  W+  + +H  E+ +  + G K D+  D
Sbjct: 1049 RYEAMSRIYYRGAKAAILCFDLTDKSSFDRIRFWIGELRQH-EEECKLYICGTKFDLVHD 873

Query: 128  D--KRVVPKGKGEQIAREHGIRFFETSAKANINIEKAFLTLAEDILRK 173
            D  +R VP+   + +A +     +ETS+    NIEK F  +AED +++
Sbjct: 872  DPERRAVPRSVAKALADDCMAEIYETSSMTGDNIEKLFTKIAEDYMKE 729
>01095
          Length = 1745

 Score = 61.2 bits (147), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 29/86 (33%), Positives = 50/86 (58%)
 Frame = -1

Query: 87   LVYDITNGKSFENISKWLRNIDEHANEDVERMLLGNKCDMDDKRVVPKGKGEQIAREHGI 146
            +VYDITN  +F     W++ +   A+ ++   L GNK D+ +KR+V   + +  A E+ +
Sbjct: 1745 VVYDITNQDTFGRAKTWVKELQRQASPNIVIALAGNKADLANKRMVEFEEAQAYAEENSL 1566

Query: 147  RFFETSAKANINIEKAFLTLAEDILR 172
             F ETSAK  +N+   FL +A+ + +
Sbjct: 1565 LFMETSAKTAMNVNDIFLAIAKKLPK 1488
>29380
          Length = 853

 Score = 55.5 bits (132), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 28/93 (30%), Positives = 50/93 (53%), Gaps = 1/93 (1%)
 Frame = -2

Query: 82  AMGIMLVYDITNGKSFENISKWLRNIDEHANEDVERMLLGNKCDMDDK-RVVPKGKGEQI 140
           A   ++VYD+    +F     W++ + +   E V  +L GNK D+  + R V     +  
Sbjct: 852 ASAAIIVYDVNIADTFSRALAWVKELRQQNTESVLIILAGNKVDLATQHRAVSFEDAQSF 673

Query: 141 AREHGIRFFETSAKANINIEKAFLTLAEDILRK 173
           ARE+G+ F E SAK  + + + F+TLA  ++++
Sbjct: 672 ARENGLLFAEVSAKTGMAVNEIFMTLANQLIQQ 574
>09827
          Length = 1201

 Score = 52.4 bits (124), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 33/118 (27%), Positives = 59/118 (50%), Gaps = 1/118 (0%)
 Frame = -3

Query: 10   FKLLLIGDSGVGKTCVLFRFSDDAFNTTFISTIGIDFKIKTVELQGKKIKLQIWDTAGQE 69
             ++L++G    GKT +L++       TT I TIG  F ++TVE   K I   +WD  GQ+
Sbjct: 1112 MRILMVGLDAAGKTTILYKLKLGEIVTT-IPTIG--FNVETVEY--KNISFTVWDVGGQD 948

Query: 70   RFHTITTSYYRGAMGIMLVYDITNGKSFENISKWL-RNIDEHANEDVERMLLGNKCDM 126
            +   +   Y++   G++ V D  + +  +   + L R ++E    D   ++  NK D+
Sbjct: 947  KIRPLWRHYFQNTQGLIFVVDSNDKERVQEAREELTRMLNEDELRDAVLLVFANKQDL 774
>31291
          Length = 446

 Score = 51.2 bits (121), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 37/118 (31%), Positives = 56/118 (47%), Gaps = 14/118 (11%)
 Frame = -1

Query: 60  LQIWDTAGQERFHTITTSYYRGAMGIMLVYDITNGKSFENIS-KWLRNIDEHANEDVERM 118
           LQ+WDTAGQE +  +    Y      ML + + +  S +N+  KW   I  H +  V  +
Sbjct: 446 LQLWDTAGQEDYDRLRPLAYPNTDVFMLXFSLMSEASMKNVKVKWYPEI-RHHDPHVPIV 270

Query: 119 LLGNKCDM-DDKRVVPK-----------GKGEQIARE-HGIRFFETSAKANINIEKAF 163
           L+G K D+  DK  V K            +G  +A+     R+FE S+K   N++ AF
Sbjct: 269 LVGTKLDLRQDKEAVRKLRSSRQDPVSSNQGNDLAKAIKAKRYFECSSKTQENLKTAF 96
>08153
          Length = 1703

 Score = 50.4 bits (119), Expect = 5e-07,   Method: Compositional matrix adjust.
 Identities = 33/119 (27%), Positives = 59/119 (49%), Gaps = 1/119 (0%)
 Frame = +1

Query: 11  KLLLIGDSGVGKTCVLFRFSDDAFNTTFISTIGIDFKIKTVELQGKKIKLQIWDTAGQER 70
           ++L++G    GKT +L++       TT I TIG  F ++TVE   K I   +WD  GQ++
Sbjct: 88  RILMVGLDAAGKTTILYKLKLGEIVTT-IPTIG--FNVETVEY--KNISFTVWDVGGQDK 252

Query: 71  FHTITTSYYRGAMGIMLVYDITNGKSFENISKWL-RNIDEHANEDVERMLLGNKCDMDD 128
              +   Y++   G++ V D  + +      + L R ++E    D   ++  NK D+ +
Sbjct: 253 IRPLWRHYFQNTQGLIFVVDSNDRERINEAKEELARMLNEDDLRDAIILVFANKQDLPN 429
>00552
          Length = 455

 Score = 49.7 bits (117), Expect = 7e-07,   Method: Compositional matrix adjust.
 Identities = 22/51 (43%), Positives = 32/51 (62%)
 Frame = -3

Query: 62  IWDTAGQERFHTITTSYYRGAMGIMLVYDITNGKSFENISKWLRNIDEHAN 112
           IWDTAGQER+ ++ T +YRG    +L + + N KS +++S W    DE  N
Sbjct: 147 IWDTAGQERYKSLRTPFYRGTDCCLLTFSVDNLKSLQSLSDW---YDEFVN 4

 Score = 42.7 bits (99), Expect = 9e-05,   Method: Compositional matrix adjust.
 Identities = 20/53 (37%), Positives = 33/53 (62%)
 Frame = -1

Query: 9   LFKLLLIGDSGVGKTCVLFRFSDDAFNTTFISTIGIDFKIKTVELQGKKIKLQ 61
           L K++L+GD GVGK+ ++ RF  + F+     TIG++F  K V + G+   +Q
Sbjct: 446 LLKVVLLGDGGVGKSSLMNRFVSNKFDAQSFHTIGVEFLTKDVVVDGETFTMQ 288
>33605
          Length = 888

 Score = 45.4 bits (106), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 27/80 (33%), Positives = 45/80 (56%)
 Frame = +1

Query: 11  KLLLIGDSGVGKTCVLFRFSDDAFNTTFISTIGIDFKIKTVELQGKKIKLQIWDTAGQER 70
           +LL++G    GKT +L +F+ +  +T    T+G  F IKT+E +G   KL +WD  GQ+ 
Sbjct: 502 RLLMLGLDNAGKTTILKKFNGEDIDT-ISPTLG--FNIKTLEHRG--FKLNVWDVGGQQS 666

Query: 71  FHTITTSYYRGAMGIMLVYD 90
             +   +Y+    G++ V D
Sbjct: 667 LRSYWRNYFESTDGLVWVVD 726
>10862
          Length = 2896

 Score = 44.7 bits (104), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 26/113 (23%), Positives = 48/113 (42%), Gaps = 1/113 (0%)
 Frame = -3

Query: 17   DSGVGKTCVLFRFSDDAFNTTFISTIGIDFKIKTVELQGKKIKLQIWDTAGQERFHTITT 76
            D  VG  C    +S     T  +     + +I+    Q ++ +  +WD  GQ++   +  
Sbjct: 2609 DPHVGA*CCRENYSSIQNETRTVCDXNTNSRIQCRNCQLQECQFNVWDVGGQDKIRPLWR 2430

Query: 77   SYYRGAMGIMLVYDITNGKSFENISKWL-RNIDEHANEDVERMLLGNKCDMDD 128
             YY G  G++ V D  +    +   + L R I++    D   ++  NK D+ D
Sbjct: 2429 HYYTGTQGLIFVVDCADRDRIDEARQELHRIINDREMRDAIILIFANKQDLPD 2271
>14775
          Length = 380

 Score = 44.3 bits (103), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 35/152 (23%), Positives = 59/152 (38%), Gaps = 1/152 (0%)
 Frame = -2

Query: 22  KTCVLFRFSDDAFNTTFISTIGIDF-KIKTVELQGKKIKLQIWDTAGQERFHTITTSYYR 80
           KTC+L R+    F    + TI +   +          ++  +WDT G E + ++  S++R
Sbjct: 379 KTCLLRRYQKGFFMDRTMPTIAVLCSEFNESRTDPLNVRYTLWDTGGAETYRSLWVSHFR 200

Query: 81  GAMGIMLVYDITNGKSFENISKWLRNIDEHANEDVERMLLGNKCDMDDKRVVPKGKGEQI 140
           GA   +LVYD+T                               C+          +G+  
Sbjct: 199 GAQVALLVYDVT-------------------------------CE----------RGQAF 143

Query: 141 AREHGIRFFETSAKANINIEKAFLTLAEDILR 172
           A + G  FFETS+    N++  F  +A  + R
Sbjct: 142 ATQCGYTFFETSSVTGKNVDAVFWEIAFILAR 47
>14119
          Length = 602

 Score = 40.8 bits (94), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 21/80 (26%), Positives = 40/80 (50%), Gaps = 1/80 (1%)
 Frame = +1

Query: 96  SFENISKWLRNIDEHANEDVERMLLGNKCDM-DDKRVVPKGKGEQIAREHGIRFFETSAK 154
           +F     W++ + +     V  +L GNK D+  + R V        A ++G+ F E SAK
Sbjct: 1   TFNRALAWVKELRQQNAGSVLIVLAGNKADLASEHRAVSADDARTFAEDNGLIFAEVSAK 180

Query: 155 ANINIEKAFLTLAEDILRKT 174
             + + + F+T+A  ++R+ 
Sbjct: 181 TGMAVSEVFMTIAHKLVRRA 240
>12443
          Length = 837

 Score = 40.0 bits (92), Expect = 6e-04,   Method: Compositional matrix adjust.
 Identities = 33/137 (24%), Positives = 67/137 (48%), Gaps = 9/137 (6%)
 Frame = -3

Query: 10  FKLLLIGDSGVGKTCVLFRFSDDAFNTTFISTIGID----FKIKTVELQGKKI--KLQIW 63
           +K++L+G +GVGKT  + + + +    T   T G+     +    ++  GK +  ++Q++
Sbjct: 580 YKVMLVGKTGVGKTSTVAKLTGNDIPLTHNETPGLQTSHLYWPGKIKHLGKTVLFQIQLF 401

Query: 64  DTAGQ---ERFHTITTSYYRGAMGIMLVYDITNGKSFENISKWLRNIDEHANEDVERMLL 120
           D AG+   +R+  I  +   G  GIM ++   +  SF+ I + L        + + ++ L
Sbjct: 400 D-AGETALKRYDHILPACQDGVDGIMFLFSFVDKGSFDEIPQLLTRFTT-LEDGICKIAL 227

Query: 121 GNKCDMDDKRVVPKGKG 137
           G K     K ++ K +G
Sbjct: 226 GTKYPFPHKGIINKDRG 176
>25796
          Length = 422

 Score = 38.9 bits (89), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 15/26 (57%), Positives = 20/26 (76%)
 Frame = -1

Query: 4  KTYDLLFKLLLIGDSGVGKTCVLFRF 29
          +TYD LFK L+IG +G GK+C+L  F
Sbjct: 83 ETYDYLFKFLIIGSAGSGKSCLLHHF 6
>10708
          Length = 2775

 Score = 38.1 bits (87), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 15/47 (31%), Positives = 27/47 (57%)
 Frame = -2

Query: 56   KKIKLQIWDTAGQERFHTITTSYYRGAMGIMLVYDITNGKSFENISK 102
            ++++L +WDTAGQE +  +    Y     I++ + I +  S ENI +
Sbjct: 2729 QQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPE 2589
>25618
          Length = 475

 Score = 37.7 bits (86), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 18/58 (31%), Positives = 32/58 (55%), Gaps = 1/58 (1%)
 Frame = +3

Query: 118 MLLGNKCDM-DDKRVVPKGKGEQIAREHGIRFFETSAKANINIEKAFLTLAEDILRKT 174
           +L GNK D+  + R V        A ++G+ F E SAK  + + + F+T+A  ++R+ 
Sbjct: 87  VLAGNKADLASEHRAVSADDARTFAEDNGLIFAEVSAKTGMAVSEVFMTIAHKLVRRA 260
>31928
          Length = 429

 Score = 37.0 bits (84), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 24/74 (32%), Positives = 42/74 (56%), Gaps = 4/74 (5%)
 Frame = +2

Query: 54  QGKKIKLQIWDTAGQERFHT---ITTSYYRGAMGIMLVYDITNGKSFENISKWLRNIDEH 110
           +G K K++I+DT       T   +   Y     G +LVYD T+ +SF  + K  ++ID+H
Sbjct: 92  RGVKEKVRIFDTGAAALETTEGDLPKHYLNFPDGFVLVYDTTSWESFRRLDKLKKDIDKH 271

Query: 111 ANE-DVERMLLGNK 123
            ++ +V  +++GNK
Sbjct: 272 RDKREVHMIVIGNK 313
>18184
          Length = 558

 Score = 27.3 bits (59), Expect = 4.3,   Method: Compositional matrix adjust.
 Identities = 13/35 (37%), Positives = 20/35 (57%)
 Frame = -3

Query: 9   LFKLLLIGDSGVGKTCVLFRFSDDAFNTTFISTIG 43
           LF +LL G    G  C++  F  ++F   F+ST+G
Sbjct: 439 LFYILLTGIVQFGYCCLVGTFPFNSFLAGFVSTVG 335
>01904
          Length = 1610

 Score = 27.3 bits (59), Expect = 4.8,   Method: Compositional matrix adjust.
 Identities = 10/23 (43%), Positives = 15/23 (65%)
 Frame = -2

Query: 19  GVGKTCVLFRFSDDAFNTTFIST 41
           GVG  C+LF   D++ NT  ++T
Sbjct: 862 GVGTCCILFHPHDNSINTCTVAT 794
>31899
          Length = 453

 Score = 26.9 bits (58), Expect = 5.2,   Method: Compositional matrix adjust.
 Identities = 18/55 (32%), Positives = 26/55 (47%)
 Frame = -1

Query: 10  FKLLLIGDSGVGKTCVLFRFSDDAFNTTFISTIGIDFKIKTVELQGKKIKLQIWD 64
             L++   SG GKTCV    + +   TT  ST  +      V    ++I LQIW+
Sbjct: 231 LDLIVQAKSGTGKTCVFSVVALEGIETTARSTQVL------VLAPTREIALQIWE 85
>06048
          Length = 2527

 Score = 26.2 bits (56), Expect = 8.5,   Method: Compositional matrix adjust.
 Identities = 14/44 (31%), Positives = 24/44 (54%)
 Frame = -1

Query: 17  DSGVGKTCVLFRFSDDAFNTTFISTIGIDFKIKTVELQGKKIKL 60
           D  V   C+L +  +DAF  T +    +  K+K + L+ +K+KL
Sbjct: 988 DKAVF*RCILHKCFEDAFYVTVLKDREV--KVKIINLKHRKVKL 863
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|61742806|ref|NP_081651.2| GRIP and coiled-coil
domain-containing 2 [Mus musculus]
         (1680 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

13299                                                                 150   5e-36
>13299
          Length = 1110

 Score =  150 bits (379), Expect = 5e-36,   Method: Compositional matrix adjust.
 Identities = 84/218 (38%), Positives = 138/218 (63%)
 Frame = -1

Query: 1137 LELVKKDAQQTTLMNMEIADYERLMKELNQKLTNKNSTIEDLXXXXXXXXXXXXTLQEEI 1196
            L    +DA+Q+ +M++EIADYER +  LN +L  +++ I DL             +Q +I
Sbjct: 654  LNAATQDAKQSDMMDLEIADYERTVHALNAQLAQRDAQIADLKAEVNRVEERVHLMQTQI 475

Query: 1197 TSLQSSVQHYEEKNTKIKQLLVKTKKELADAKQAETDHLLLQASLKGELEASQQQVEVYK 1256
             +++ +    EE+  K+KQLLVKTKK LAD+++ ET+   +   L+G+LEA  QQVE YK
Sbjct: 474  EAVEENRVQAEERANKLKQLLVKTKKXLADSRKQETEQKSMDLELRGQLEAVNQQVEEYK 295

Query: 1257 IQLAEMTSEKHKIHEHLKTSAEQHQRTLSAYQQRVVALQEESRAAKAEQAAVTSEFESYK 1316
            +Q+ E+ ++  ++ E L++  E HQRT+ + + R+ AL ++    ++E  AV +E++SYK
Sbjct: 294  VQMGEVGADNQRLQEKLRSLTESHQRTVRSLEARLTALTDDLEVTRSELRAVQTEYDSYK 115

Query: 1317 VRVHNVLKQQKNKSVSQVETEGAKQEREHLEMLIDQLK 1354
            VR H+VL +QK KS +   ++  K ER+ LE  ++QLK
Sbjct: 114  VRAHSVLTKQKTKSPADTVSDMEKLERQRLEGAVEQLK 1
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|160333224|ref|NP_036011.3| G protein-coupled receptor
kinase 1 [Mus musculus]
         (564 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

27405                                                                 148   6e-36
30755                                                                 142   3e-34
18484                                                                 127   1e-29
26560                                                                 115   4e-26
03240                                                                 109   3e-24
31885                                                                 108   5e-24
15910                                                                  96   3e-20
18921                                                                  96   5e-20
18663                                                                  92   5e-19
13212                                                                  88   1e-17
12721                                                                  85   6e-17
21079                                                                  85   7e-17
13592                                                                  84   1e-16
01060                                                                  83   3e-16
14420                                                                  82   5e-16
09606                                                                  80   3e-15
19094                                                                  77   3e-15
01707                                                                  74   1e-13
00392                                                                  71   9e-13
19761                                                                  71   9e-13
00300                                                                  71   1e-12
14126                                                                  71   1e-12
17722                                                                  70   2e-12
01718                                                                  70   2e-12
21433                                                                  69   5e-12
25019                                                                  55   1e-11
01392                                                                  67   3e-11
00715                                                                  66   3e-11
16708                                                                  66   4e-11
11185                                                                  65   1e-10
26711                                                                  64   2e-10
00486                                                                  64   2e-10
01966                                                                  63   4e-10
29581                                                                  63   4e-10
09007                                                                  62   9e-10
14116                                                                  61   2e-09
13066                                                                  60   3e-09
04591                                                                  60   3e-09
26156                                                                  45   4e-09
12672                                                                  58   9e-09
17975                                                                  57   2e-08
04852                                                                  57   2e-08
01756                                                                  57   2e-08
21808                                                                  55   8e-08
28638                                                                  54   2e-07
03508                                                                  54   2e-07
06405                                                                  54   2e-07
02638                                                                  54   2e-07
07940                                                                  52   8e-07
07836                                                                  52   8e-07
19301                                                                  50   3e-06
04138                                                                  49   6e-06
28157                                                                  48   1e-05
27546                                                                  47   2e-05
29590                                                                  42   2e-05
11780                                                                  47   3e-05
38560                                                                  46   5e-05
20152                                                                  45   6e-05
37602                                                                  44   2e-04
32957                                                                  42   5e-04
17300                                                                  42   5e-04
31489                                                                  41   0.001
21210                                                                  39   0.005
26009                                                                  39   0.006
14477                                                                  38   0.010
20640                                                                  38   0.012
18481                                                                  38   0.013
27274                                                                  38   0.014
17516                                                                  36   0.032
18996                                                                  36   0.035
08294                                                                  36   0.039
11404                                                                  35   0.086
29360                                                                  35   0.12 
17253                                                                  34   0.13 
21800                                                                  34   0.17 
01106                                                                  33   0.28 
33586                                                                  31   1.4  
21418                                                                  30   3.2  
36481                                                                  30   3.3  
>27405
          Length = 532

 Score =  148 bits (373), Expect = 6e-36,   Method: Compositional matrix adjust.
 Identities = 79/182 (43%), Positives = 110/182 (60%), Gaps = 5/182 (2%)
 Frame = -3

Query: 200 GFGEVSACQMKATGKMYACXXXXXXXXXXXXGYQGAIVEKRILTKVH----SRFIVSLAY 255
           GFGEV  C+   TGKMYA             G   A+ E+ +L+ V     S FIV + Y
Sbjct: 530 GFGEVYGCRKADTGKMYAMKCLDKKRIKMKGGETLALNERIMLSLVSTGEGSPFIVCMTY 351

Query: 256 AFETKTDLCLVMTIMNGGDVRYHIYNVDEDNPGFSEPRAIYYTAQIISGLEHLHQRRIVY 315
           AF+T   LC ++ +MNGGD+ YH+      +  F+E    +Y A+++ GLEH+H R +VY
Sbjct: 350 AFQTPEKLCFILDLMNGGDLHYHL----SQHGVFTEKEVRFYAAEVMLGLEHMHSRFVVY 183

Query: 316 RDLKPENVLLDNDGNIRISDLGLAVELKEGQNKTKGYAGTPGFMAPE-LLRGEEYDFSVD 374
           RDLKP N+LLD +G++RISDLGLA +    + K     GT G+MAPE L++G+ YD S D
Sbjct: 182 RDLKPANILLDENGHVRISDLGLACDFS--KKKPHASVGTHGYMAPEVLMKGQAYDSSAD 9

Query: 375 YF 376
           +F
Sbjct: 8   WF 3
>30755
          Length = 1137

 Score =  142 bits (358), Expect = 3e-34,   Method: Compositional matrix adjust.
 Identities = 76/186 (40%), Positives = 105/186 (56%)
 Frame = +2

Query: 289 FSEPRAIYYTAQIISGLEHLHQRRIVYRDLKPENVLLDNDGNIRISDLGLAVELKEGQNK 348
           F+E R  +Y A+IIS L +LH + I+YRDLK EN+LLD DG+I+++D GL  E       
Sbjct: 23  FTEERTRFYGAEIISALGYLHSQGIIYRDLKLENLLLDKDGHIKVADFGLCKEDITYGRT 202

Query: 349 TKGYAGTPGFMAPELLRGEEYDFSVDYFALGVTLYEMIAARGPFRARGEKVENKELKQRI 408
           TK + GTP ++APE+L   +Y  +VD++  GV +YEMI  R PF  R   V    L   I
Sbjct: 203 TKTFCGTPEYLAPEVLDDNDYGRAVDWWGTGVVMYEMICGRLPFYNRDHDV----LFTLI 370

Query: 409 ISEPVKYPEKFSQASKDFCEQLLEKDPEKRLGFRDGTCDALRANVLFKDISWRQLEAGML 468
           + E VK+P   +  +K     LL KDP  RLG        ++A+  F  I+W  L    +
Sbjct: 371 LVEDVKFPRNITDEAKSLLSGLLAKDPRNRLGGGQDDVKEIQAHPFFASINWTDLVQKKI 550

Query: 469 IPPFIP 474
            PPF P
Sbjct: 551 TPPFKP 568
>18484
          Length = 635

 Score =  127 bits (319), Expect = 1e-29,   Method: Compositional matrix adjust.
 Identities = 65/152 (42%), Positives = 94/152 (61%)
 Frame = +1

Query: 289 FSEPRAIYYTAQIISGLEHLHQRRIVYRDLKPENVLLDNDGNIRISDLGLAVELKEGQNK 348
           F EP A +Y A+I  GL  LH + I+YRDLK +NV+LD++G+I+I+D G+  E   G   
Sbjct: 34  FKEPVAAFYAAEIAVGLFFLHDQGIIYRDLKLDNVMLDSEGHIKIADFGMCKEGMTGDAT 213

Query: 349 TKGYAGTPGFMAPELLRGEEYDFSVDYFALGVTLYEMIAARGPFRARGEKVENKELKQRI 408
           T+ + GTP ++APE++  + Y  SVD++A GV L+EM+A + PF    E     EL   I
Sbjct: 214 TRTFCGTPDYIAPEIVLYQPYSKSVDWWAYGVLLFEMLAGQPPFDGEDE----DELFSSI 381

Query: 409 ISEPVKYPEKFSQASKDFCEQLLEKDPEKRLG 440
               V YP+  S+ +   C+ LL K+P KRLG
Sbjct: 382 TDHNVSYPKAMSREAVSLCKGLLMKNPTKRLG 477
>26560
          Length = 398

 Score =  115 bits (289), Expect = 4e-26,   Method: Composition-based stats.
 Identities = 53/125 (42%), Positives = 80/125 (64%), Gaps = 1/125 (0%)
 Frame = -1

Query: 274 DVRYHIYNVDEDNPGFSEPRAIYYTAQIISGLEHLHQRRIVYRDLKPENVLLDNDGNIRI 333
           D+ YH+      +  F+E    +Y A+++ GLEH+H R +VYRDLKP N+LLD +G++RI
Sbjct: 398 DLHYHL----SQHGVFTEKEVRFYAAEVMLGLEHMHSRFVVYRDLKPANILLDENGHVRI 231

Query: 334 SDLGLAVELKEGQNKTKGYAGTPGFMAPE-LLRGEEYDFSVDYFALGVTLYEMIAARGPF 392
           SDLGLA +    + +     GT G+MAPE L++G+ YD S D+F+ G  LY+++    PF
Sbjct: 230 SDLGLACDFS--KKRPHASVGTHGYMAPEVLMKGQSYDSSADWFSFGCMLYKLLKGHSPF 57

Query: 393 RARGE 397
           R   +
Sbjct: 56  RQHNQ 42
>03240
          Length = 1683

 Score =  109 bits (273), Expect = 3e-24,   Method: Compositional matrix adjust.
 Identities = 90/364 (24%), Positives = 155/364 (42%), Gaps = 49/364 (13%)
 Frame = -3

Query: 190  FLDFRVLGKGGFGEVSACQMKATGKMYACXXXXXXXXXXXXGYQGAIVEKRILTKVHSRF 249
            F   + LG G FGEVS C+   TG +YA                    E+ IL +  + +
Sbjct: 1285 FEKIKTLGVGAFGEVSLCRKNDTGMLYAMKTLRKSDVLKRNQVAHVKAERDILAEADNEW 1106

Query: 250  IVSLAYAFETKTDLCLVMTIMNGGDVRYHIYNVDEDNPGFSEPRAIYYTAQIISGLEHLH 309
            +V L Y+F+    L  VM  + GGD+   +  ++       EP A +Y A+++  +E +H
Sbjct: 1105 VVKLYYSFQDHNYLYFVMDYVPGGDLMGLLIRME----ILDEPLARFYVAELVQAIESVH 938

Query: 310  QRRIVYRDLKPENVLLDNDGNIRISDLGLAVELKEGQNK--------------------- 348
            +   ++RD+KP+N+L+D +G+I+++D GL    +   N                      
Sbjct: 937  RMGFIHRDIKPDNILIDRNGHIKLTDFGLCTGFRWTHNSKYYQRDGTHARQDSMEVKCQL 758

Query: 349  -----------------------TKGYAGTPGFMAPELL-RGEEYDFSVDYFALGVTLYE 384
                                        GTP ++APE+L R   Y    D++++GV L+E
Sbjct: 757  DEQCQCEILKPLERRRKREQRCLAHSLVGTPNYIAPEVLSRLGGYTSVCDWWSVGVILFE 578

Query: 385  MIAARGPFRARGEKVENKELKQRIIS--EPVKYPEK--FSQASKDFCEQLLEKDPEKRLG 440
            M+    PF A        E + ++I+  + +K P +   SQ +KD   +L     + RLG
Sbjct: 577  MLVGHPPFYANTP----AETQYKVINWKDMLKIPRESNLSQPAKDLILRLC-CGSDDRLG 413

Query: 441  FRDGTCDALRANVLFKDISWRQLEAGMLIPPFIPDSRTVYAKNIQDVGAFSTVKGVVFDK 500
                    ++ ++ F  +++  L      PP++P+ R  YA    D   F  V       
Sbjct: 412  L--NGAGEIKTHMFFAGVNFETLRKQQ--PPYVPNIR--YA---TDTSNFDPVDPDKLRN 260

Query: 501  ADTE 504
            +D+E
Sbjct: 259  SDSE 248
>31885
          Length = 529

 Score =  108 bits (270), Expect = 5e-24,   Method: Compositional matrix adjust.
 Identities = 58/163 (35%), Positives = 99/163 (60%), Gaps = 7/163 (4%)
 Frame = -2

Query: 241 ILTKVHSRFIVSLAYAFETKTDLCLVMTIMNGGDVRYHIYNVDEDNPGFSEPRAIYYTAQ 300
           +LT++   F+V+L YAF+ + DL +V+ +  GGD+RYH+    +    F E    +Y  Q
Sbjct: 513 MLTRLDHPFLVNLWYAFQDEEDLFMVVDLFLGGDLRYHM----QQEVSFREDCVKFYLCQ 346

Query: 301 IISGLEHLHQRRIVYRDLKPENVLLDNDGNIRISDLGLAVELKEGQNKTKGYAGTPGFMA 360
           +   L++L  ++IV+RD+KP+N+LLD  G+  ++D  +A +L++ +  T   +GT  +MA
Sbjct: 345 LALVLDYLRSQKIVHRDIKPDNILLDEQGHCHVTDFNIATQLEDDELATST-SGTRPYMA 169

Query: 361 PELL-------RGEEYDFSVDYFALGVTLYEMIAARGPFRARG 396
           PE+        RG  Y F VD+++LGV+L+E++  R PF    
Sbjct: 168 PEVYGVAINERRG--YGFPVDWWSLGVSLFELLKKRRPFSVHS 46
>15910
          Length = 1361

 Score = 95.9 bits (237), Expect = 3e-20,   Method: Compositional matrix adjust.
 Identities = 54/158 (34%), Positives = 95/158 (60%), Gaps = 7/158 (4%)
 Frame = +2

Query: 289 FSEPRAIYYTAQIISGLEHLHQRRIVYRDLKPENVL---LDNDGNIRISDLGLAVELKEG 345
           ++E  A    + I+ G++++H   +V+RDLKPEN+L   + +D  ++++D GL+  + E 
Sbjct: 455 YTEKDAARAISDILHGVQYIHANGVVHRDLKPENLLYECMTDDSKLKLADFGLS-RIIEP 631

Query: 346 QNKTKGYAGTPGFMAPELLRGEEYDFSVDYFALGVTLYEMIAARGPFRARGEKVENKELK 405
           + +     GTPG+ APE+L+G++Y  SVD +++GV  Y ++    PF A  E     E+ 
Sbjct: 632 EVQMSTVCGTPGYCAPEVLKGDKYTPSVDMWSVGVIAYILLCGYEPFFAENE----FEMY 799

Query: 406 QRIISEPVKYPEKF----SQASKDFCEQLLEKDPEKRL 439
           ++II    K+ E++    S+ +KD   +LL  DP+KRL
Sbjct: 800 RKIIKGEYKFDEEYWSEISENAKDVVRKLLVIDPKKRL 913
>18921
          Length = 697

 Score = 95.5 bits (236), Expect = 5e-20,   Method: Compositional matrix adjust.
 Identities = 64/206 (31%), Positives = 102/206 (49%)
 Frame = +2

Query: 187 EDWFLDFRVLGKGGFGEVSACQMKATGKMYACXXXXXXXXXXXXGYQGAIVEKRILTKVH 246
           ED F     LG+G +G V     K TG++ A               Q  I E  I+ +  
Sbjct: 26  EDVFDILGKLGEGSYGSVFKSLHKETGQVLAIKQVPVDTDL-----QEIIKEISIMQQCD 190

Query: 247 SRFIVSLAYAFETKTDLCLVMTIMNGGDVRYHIYNVDEDNPGFSEPRAIYYTAQIISGLE 306
           S++IV    ++   TDL +VM     G V   +   ++          +YYT   + GL 
Sbjct: 191 SKYIVKYYGSYFKNTDLWIVMEYCGAGSVSDIMRLRNKTLVEREIATILYYT---LKGLX 361

Query: 307 HLHQRRIVYRDLKPENVLLDNDGNIRISDLGLAVELKEGQNKTKGYAGTPGFMAPELLRG 366
           +LH RR ++RD+K  N+LL+N+G+ +++D G+A +L +   K     GTP +MAPE+++ 
Sbjct: 362 YLHSRRKIHRDIKAGNILLNNEGHAKLADFGVAGQLTDTMAKRNTVIGTPYWMAPEVIQE 541

Query: 367 EEYDFSVDYFALGVTLYEMIAARGPF 392
             YD   D ++LG+T  EM   + P 
Sbjct: 542 IGYDCVADIWSLGITALEMAEGKPPV 619
>18663
          Length = 600

 Score = 92.0 bits (227), Expect = 5e-19,   Method: Compositional matrix adjust.
 Identities = 52/130 (40%), Positives = 72/130 (55%), Gaps = 7/130 (5%)
 Frame = +2

Query: 352 YAGTPGFMAPELLRGEEYDFSVDYFALGVTLYEMIAARGPFRARGEKVENKE------LK 405
           + GTP ++APE+LRGE+Y FSVD++ALGV LYEM+A R PF   G   EN +      L 
Sbjct: 8   FCGTPNYIAPEILRGEDYGFSVDWWALGVLLYEMLAGRSPFDIAGAS-ENPDQNTEDYLF 184

Query: 406 QRIISEPVKYPEKFSQASKDFCEQLLEKDPEKRLG-FRDGTCDALRANVLFKDISWRQLE 464
           Q I+ + ++ P   S  +    +  L K+P  RLG  R+     +  +  FK I W  LE
Sbjct: 185 QVILEKTIRIPRSLSVKAASVLKGFLNKNPADRLGCHRESAFMDIVNHPFFKVIDWEMLE 364

Query: 465 AGMLIPPFIP 474
              + PPF P
Sbjct: 365 RKQVSPPFKP 394
>13212
          Length = 1067

 Score = 87.8 bits (216), Expect = 1e-17,   Method: Compositional matrix adjust.
 Identities = 56/170 (32%), Positives = 92/170 (54%), Gaps = 13/170 (7%)
 Frame = -1

Query: 282  VDEDNPGFSEPRAIYYTAQIISGLEHLHQRRIVYRDLKPENVLLDNDGNIRISDLGLAVE 341
            VD + P  +E +  Y   ++   L+ LH+  +++RD+K  NVLL  DG ++++D G++ +
Sbjct: 1007 VDLEKP-MTEAQICYVCHEMCMALDFLHRHHVIHRDIKAGNVLLTIDGEVKLADFGVSAK 831

Query: 342  LKEGQNKTKGYAGTPGFMAPEL-----LRGEEYDFSVDYFALGVTLYEMIAARGPFRARG 396
              + Q K   + GTP +MAPE+     L+   YDF  D ++LGVTL E      P     
Sbjct: 830  NTQTQQKRDTFIGTPYWMAPEVVLCETLKDTPYDFKADIWSLGVTLIEFAQIEPP----- 666

Query: 397  EKVENKELK-QRII-----SEP--VKYPEKFSQASKDFCEQLLEKDPEKR 438
                NKE+   R++     S+P  ++ P+K+++  KDF  + L KDP  R
Sbjct: 665  ----NKEMHPMRVLIKIHKSDPPTLEKPKKWTKLFKDFIAKCLVKDPNLR 528
>12721
          Length = 821

 Score = 85.1 bits (209), Expect = 6e-17,   Method: Compositional matrix adjust.
 Identities = 55/202 (27%), Positives = 97/202 (48%), Gaps = 1/202 (0%)
 Frame = +1

Query: 238 EKRILTKVHSRFIVSLAYAFETKTDLCLVMTIMNGGDVRYHIYNVDEDNPGFSEPRAIYY 297
           E  ++   H   IV +  ++    +L +VM  M GG +   + N   D     E +    
Sbjct: 226 EVVVMRDYHHPNIVEMYNSYLVNDELWVVMEFMEGGALTDIVTNNRMD-----EVQIATV 390

Query: 298 TAQIISGLEHLHQRRIVYRDLKPENVLLDNDGNIRISDLGLAVELKEGQNKTKGYAGTPG 357
               +  L  LH   +++RD+K +++LL +DG +++ D G   ++ +   K K   GTP 
Sbjct: 391 CRACLKALAFLHANGVIHRDIKSDSILLSHDGKVKLXDFGFCAQVTQDLQKRKSLVGTPY 570

Query: 358 FMAPELLRGEEYDFSVDYFALGVTLYEMIAARGPFRARGEKVENKELKQRIISEP-VKYP 416
           +MAPE++    Y   VD ++LG+ + EMI A  PF    E       + R +  P ++  
Sbjct: 571 WMAPEVISRLPYGPEVDIWSLGIMVMEMIDAEPPF--FNEPPLQAMRRIRDMPPPKLRNT 744

Query: 417 EKFSQASKDFCEQLLEKDPEKR 438
            K S   + F +++L +DP +R
Sbjct: 745 HKISPRLQGFIDRMLVRDPHQR 810
>21079
          Length = 878

 Score = 85.1 bits (209), Expect = 7e-17,   Method: Compositional matrix adjust.
 Identities = 49/141 (34%), Positives = 79/141 (56%), Gaps = 2/141 (1%)
 Frame = +1

Query: 256 AFETKTDLCLVMTIMNGGDVRYHIYNVDEDNPGFSEPRAIYYTAQIISGLEHLHQRRIVY 315
           AFE    + LVM  +  G++      V  D+   +E   +++  QI SG+ ++H + I++
Sbjct: 28  AFEAPRTMVLVMEFVGAGEL---FERVIRDDFVLTERDCVHFVRQICSGVGYMHTQSILH 198

Query: 316 RDLKPENVLL--DNDGNIRISDLGLAVELKEGQNKTKGYAGTPGFMAPELLRGEEYDFSV 373
            DLKPENVL   DN   I+I D GLA   K G +  +   GTP F+APE++  +E +F+ 
Sbjct: 199 LDLKPENVLCVSDNSNQIKIIDFGLARFYKPG-DSLQVLFGTPEFIAPEVVNYDEINFTT 375

Query: 374 DYFALGVTLYEMIAARGPFRA 394
           D +++GV  Y +++   P R 
Sbjct: 376 DMWSIGVICYILLSGLSPSRV 438
>13592
          Length = 980

 Score = 84.3 bits (207), Expect = 1e-16,   Method: Compositional matrix adjust.
 Identities = 66/253 (26%), Positives = 123/253 (48%), Gaps = 9/253 (3%)
 Frame = +2

Query: 196 LGKGGFGEVSACQMKATGKMYACXXXXXXXXXXXXGYQGAIVEKRILTKVHSRFIVSLAY 255
           +G+G FG+V       TG++ A               +    E +IL  +  + +V   Y
Sbjct: 8   IGQGRFGKVYTAVNNNTGELMA-MKEIAIQPGETRALKNVAEELKILEGIKHKNLVRY-Y 181

Query: 256 AFET-KTDLCLVMTIMNGGDVRYHIYNVDEDNPGFSEPRAIYYTAQIISGLEHLHQRRIV 314
             E  + +L + M + + G +     ++ E   G  E  +  +TAQ++SG+  LH+  IV
Sbjct: 182 GIEVHREELLIFMELCSEGTLE----SLVELTGGLPEALSRRFTAQLLSGVAELHKHGIV 349

Query: 315 YRDLKPENV-LLDNDGNIRISDLGLAVELKEGQN---KTKGYAGTPGFMAPELLRGEEYD 370
           +RD+K  N+ L+D   ++++ D G AV+++       + +GY GT  +MAPE+      D
Sbjct: 350 HRDIKTANIFLVDGSNSLKLGDFGSAVKIQAHTTVPGELQGYVGTQAYMAPEVFTKTNSD 529

Query: 371 FS---VDYFALGVTLYEMIAARGPFRARGEKVENKELKQRI-ISEPVKYPEKFSQASKDF 426
                 D +++G  + EM + + P+    +   N ++  ++ + E  + PE  SQ   DF
Sbjct: 530 GHGRLADIWSVGCVVVEMASGKRPW---AQFDSNFQIMFKVGMGEKPQAPESLSQEGHDF 700

Query: 427 CEQLLEKDPEKRL 439
            +  L+ DP++RL
Sbjct: 701 IDHCLQHDPKQRL 739
>01060
          Length = 1800

 Score = 82.8 bits (203), Expect = 3e-16,   Method: Compositional matrix adjust.
 Identities = 68/231 (29%), Positives = 110/231 (47%), Gaps = 5/231 (2%)
 Frame = +1

Query: 192 DFRVLGKGGFGEVSACQMKATGKMYACXXXXXXXXXXXXGYQGAIVEKRILTKVHSRFIV 251
           DF+ +G+G +G V  C+ +ATG+  A                 AI E  +L ++    IV
Sbjct: 85  DFQKIGEGTYGVVYKCRHRATGRKLAMKKIRLRGSEDGVP-SSAIREIAMLRELRHTNIV 261

Query: 252 SLAYAFETKTDLCLVMTIMNGGDVRYHIYNVDEDNPGFSEPRAIY--YTAQIISGLEHLH 309
            L         L LV   ++  D++ +I   D+   G    R +   Y  QI++G+   H
Sbjct: 262 CLEDVIMEDERLFLVFEFLSM-DLKMYI---DKFPEGVVLDRRLVKSYVFQIVTGIXFCH 429

Query: 310 QRRIVYRDLKPENVLLDNDGNIRISDLGLAVELKEGQNKTKGYAGTPGFMAPELLRG-EE 368
           QRRIV+RDLKP+N+L+++ G I+I+D G+A               T  + APE+L G  +
Sbjct: 430 QRRIVHRDLKPQNLLINHTGAIKIADFGMARTFALPVRAYTHEVVTLWYRAPEILMGASK 609

Query: 369 YDFSVDYFALGVTLYEMIAARGPFRARGEKVENKELKQRIISEPVK--YPE 417
           Y   VD +++G    +M+  R P      +++      RII  P +  +PE
Sbjct: 610 YSTPVDVWSIGTIFADML-IRTPIFKGDSEIDQLFKIFRIIGTPTEQTWPE 759
>14420
          Length = 528

 Score = 82.4 bits (202), Expect = 5e-16,   Method: Compositional matrix adjust.
 Identities = 45/157 (28%), Positives = 84/157 (53%)
 Frame = +2

Query: 236 IVEKRILTKVHSRFIVSLAYAFETKTDLCLVMTIMNGGDVRYHIYNVDEDNPGFSEPRAI 295
           I E  ++ +  +  IV+   ++    +L +VM  + GG +   +     D     E +  
Sbjct: 44  INEILVMRENQNPNIVNYLDSYLVGEELWVVMEFLAGGSLTDVVTETCMD-----EGQIA 208

Query: 296 YYTAQIISGLEHLHQRRIVYRDLKPENVLLDNDGNIRISDLGLAVELKEGQNKTKGYAGT 355
               + +  LE LH+ ++++RD+K +N+LL  DG+++++D G   +L   Q+K     GT
Sbjct: 209 AVCRECLQALEFLHENQVIHRDIKSDNILLGMDGSVKLTDFGFCAQLSPEQSKRSTMVGT 388

Query: 356 PGFMAPELLRGEEYDFSVDYFALGVTLYEMIAARGPF 392
           P +MAPE++  ++Y  +VD ++LGV   EMI    P+
Sbjct: 389 PYWMAPEVVTRKQYGPTVDIWSLGVMCIEMIEGEPPY 499
>09606
          Length = 1300

 Score = 79.7 bits (195), Expect = 3e-15,   Method: Compositional matrix adjust.
 Identities = 56/218 (25%), Positives = 96/218 (44%), Gaps = 26/218 (11%)
 Frame = -3

Query: 250 IVSLAYAFETKTDLCLVMTIMNGGDVRYHIYNVDEDNPGFSEPRAIYYTAQIISGLEHLH 309
           +V     +ET   L LV+ +  GG     + ++   +    E     +   +++GL ++H
Sbjct: 947 VVQFHEWYETSNHLWLVVELCTGGS----LADILAQDHHLPETSIRDFGIHLVTGLHYIH 780

Query: 310 QRRIVYRDLKPENVLLDNDGNIRISDLGLA----------------------VELKEGQN 347
              I++ DL+P  VLLD  G ++ +D GL+                      ++  E   
Sbjct: 779 SLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEAGDQWNIQSAEEMM 600

Query: 348 KTKGYAGTPGFMAPELLRGEEYDFSVDYFALGVTLYEMIAARGPFRARGEKV-ENKELKQ 406
           K    +G+P +MAPE+ +G E     D +ALG   YEM +   PF      + ++K L +
Sbjct: 599 KQVPTSGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFSGHPPFLGETYDITKDKVLNK 420

Query: 407 RIISEPVKYPEKFSQASKDF---CEQLLEKDPEKRLGF 441
                 VK     ++ S +F    E LL+KD  +RL +
Sbjct: 419 EFPLPKVKGSRLSAKPSPEFLNLLESLLQKDSTRRLSW 306
>19094
          Length = 898

 Score = 76.6 bits (187), Expect(2) = 3e-15,   Method: Compositional matrix adjust.
 Identities = 37/91 (40%), Positives = 60/91 (65%)
 Frame = +1

Query: 295 IYYTAQIISGLEHLHQRRIVYRDLKPENVLLDNDGNIRISDLGLAVELKEGQNKTKGYAG 354
           +YYT   + GL +LH RR ++RD+K  N+LL+N+G+ +++D G+A +L +   K     G
Sbjct: 76  LYYT---LKGL*YLHSRRKIHRDIKAGNILLNNEGHAKLADFGVAGQLTDTMAKRNTVIG 246

Query: 355 TPGFMAPELLRGEEYDFSVDYFALGVTLYEM 385
           TP +MAPE+++   YD   D ++LG+T  EM
Sbjct: 247 TPYWMAPEVIQEIGYDCVADIWSLGITALEM 339

 Score = 23.5 bits (49), Expect(2) = 3e-15,   Method: Compositional matrix adjust.
 Identities = 13/33 (39%), Positives = 15/33 (45%), Gaps = 6/33 (18%)
 Frame = +3

Query: 412 PVKYPEKFSQASK------DFCEQLLEKDPEKR 438
           P K P  F Q  K      DF  + L K+PE R
Sbjct: 396 PTKPPPSFRQPDKWSTEFIDFVSKCLVKNPENR 494
>01707
          Length = 757

 Score = 73.9 bits (180), Expect = 1e-13,   Method: Compositional matrix adjust.
 Identities = 60/233 (25%), Positives = 105/233 (45%), Gaps = 7/233 (3%)
 Frame = +1

Query: 196 LGKGGFGEVSACQMKATGKMYACXXXXXXXXXXXXGYQGAIVEKRILTKVHSRFIVSLAY 255
           +G+G +G V  C+ K T ++ A               + A+ E R+L ++    +V L  
Sbjct: 88  IGEGSYGVVFKCRNKETSQLVAIKKFVESEDDPLIK-KIAMREIRMLKQLKHPNLVRLIE 264

Query: 256 AFETKTDLCLVM-----TIMNGGDVRYHIYNVDEDNPGFSEPRAIYYTAQIISGLEHLHQ 310
            F  K  L LV      T++N          +D    G  EP       Q +  +   HQ
Sbjct: 265 VFRRKKRLHLVFDYVDHTLLN---------ELDRYPRGLPEPMVKRIIYQTLLAVNFCHQ 417

Query: 311 RRIVYRDLKPENVLLDNDGNIRISDLGLAVELKEGQNKTKGYAGTPGFMAPELLRGE-EY 369
              ++RD+KPEN+L+   G +++ D G A  L    ++   Y  T  + APELL G+ +Y
Sbjct: 418 YNTIHRDVKPENILITRQGQVKLCDFGFARILTGPGDEYTDYVATRWYRAPELLVGDTQY 597

Query: 370 DFSVDYFALGVTLYEMIAARGPFRARGEKVENKELKQRIISEPV-KYPEKFSQ 421
              VD +A+G    E++  +  +  R + V+   L ++ + + + ++ E FS 
Sbjct: 598 GPPVDVWAIGCVFAELLTGQALWPGRSD-VDQLHLIRKTLGDLIPRHIEIFSN 753
>00392
          Length = 668

 Score = 71.2 bits (173), Expect = 9e-13,   Method: Compositional matrix adjust.
 Identities = 43/133 (32%), Positives = 73/133 (54%), Gaps = 3/133 (2%)
 Frame = +3

Query: 263 LCLVMTIMNGGDVRYHIYNVDEDNPGFSEPRAIYYTAQIISGLEHLHQRR--IVYRDLKP 320
           + LV  +M  G ++ ++    + N    +     +  Q++ GL  LH R   +++RDLK 
Sbjct: 171 IILVTELMTSGTLKTYLKRFKKPNVKILKN----WCRQVLKGLYFLHTRTPPVIHRDLKC 338

Query: 321 ENVLLDN-DGNIRISDLGLAVELKEGQNKTKGYAGTPGFMAPELLRGEEYDFSVDYFALG 379
           +N+ +    G+++I DLGLA    + Q+  K   GTP FMAPE+   E YD +VD +A G
Sbjct: 339 DNIFITGPTGSVKIGDLGLAT--LKNQSFAKSVIGTPEFMAPEMYE-EHYDEAVDVYAFG 509

Query: 380 VTLYEMIAARGPF 392
           + + EM ++  P+
Sbjct: 510 MCMLEMASSEYPY 548
>19761
          Length = 473

 Score = 71.2 bits (173), Expect = 9e-13,   Method: Compositional matrix adjust.
 Identities = 42/149 (28%), Positives = 74/149 (49%), Gaps = 2/149 (1%)
 Frame = -3

Query: 288 GFSEPRAIYYTAQIISGLEHLHQRR--IVYRDLKPENVLLDNDGNIRISDLGLAVELKEG 345
           G  E   + +  Q  S L ++H     I++RDLKP+N+ +   G++R+ DLGLA +L   
Sbjct: 435 GLPERLIVCWLMQTASALNYMHTHTPVILHRDLKPQNIYVTEKGDVRLGDLGLARKLTGP 256

Query: 346 QNKTKGYAGTPGFMAPELLRGEEYDFSVDYFALGVTLYEMIAARGPFRARGEKVENKELK 405
            +      GT  +++PE+L  + Y+   D ++LG   Y++   +G      E      L 
Sbjct: 255 ADFATSQVGTIMYLSPEILSQQPYNSKSDIWSLGCVFYDITGKKG----SDEMGVMFLLV 88

Query: 406 QRIISEPVKYPEKFSQASKDFCEQLLEKD 434
           Q +    +  P+ +SQ  +D   ++L KD
Sbjct: 87  QVMGGRKLPLPDHYSQEFRDTISRMLTKD 1
>00300
          Length = 2318

 Score = 71.2 bits (173), Expect = 1e-12,   Method: Compositional matrix adjust.
 Identities = 63/275 (22%), Positives = 115/275 (41%), Gaps = 8/275 (2%)
 Frame = -1

Query: 172  LRFLQWKWLEAQPIGEDWFLDFRVLGKGGFGEVSACQMKATGKMYACXXXXXXXXXXXXG 231
            +R + ++W     IGE           G FG+V      +TG++ A              
Sbjct: 1673 VRRVNFRWQRGNKIGE-----------GQFGKVYTAVNMSTGELMALKEMKFQPNDLQQ- 1530

Query: 232  YQGAIVEKRILTKVHSRFIVSLAYAFETKTD-LCLVMTIMNGGDVRYHIYNVDEDNPGFS 290
             +    E +I   +    +V   Y  E   D + + M   + G +       +    G  
Sbjct: 1529 LREMCDEIKIFEGIQHENLVKY-YGVEVHKDEMLMFMEYCDTGTIE------EAAKMGLP 1371

Query: 291  EPRAIYYTAQIISGLEHLHQRRIVYRDLKPENVLLDNDGNIRISDLGLAVELKEGQN--- 347
            E     YT +I+  + HLH+  IV+RD+K  N+ L ++G++++ D G +V+LK       
Sbjct: 1370 EYLIRRYTREIVLAVNHLHENSIVHRDIKGANIFLTSNGHVKLGDFGCSVKLKSHTTMPG 1191

Query: 348  KTKGYAGTPGFMAPELLRGEE---YDFSVDYFALGVTLYEMIAARGPFRARGEKVENKEL 404
            +     GT  +MAPE+    +   Y  + D ++LG  + EM   + P+    +   N ++
Sbjct: 1190 EFHNLVGTTAYMAPEVFTQNDQGGYGRAADIWSLGCVVIEMATGKRPWH---DLDNNYQI 1020

Query: 405  KQRI-ISEPVKYPEKFSQASKDFCEQLLEKDPEKR 438
              ++ I      P+  S   K F + ++  DP +R
Sbjct: 1019 MYKVGIGHKPAVPDSLSVEGKHFLDLIMCHDPAQR 915
>14126
          Length = 1265

 Score = 70.9 bits (172), Expect = 1e-12,   Method: Compositional matrix adjust.
 Identities = 55/184 (29%), Positives = 88/184 (47%), Gaps = 15/184 (8%)
 Frame = +3

Query: 286 NPGFSEPRAIYYTAQIISGLEHLHQRRIVYRDLKPENVLLDNDGNIRISDLGLAVELKEG 345
           +PG    R      Q+++G++ LH  RIV+RDLKP+N+L+  DG ++++D GLA  +   
Sbjct: 498 SPGLGPDRIKDLMLQLLNGVDFLHSNRIVHRDLKPQNLLISKDGRLKLADFGLA-RIYSF 674

Query: 346 QNKTKGYAGTPGFMAPELLRGEEYDFSVDYFALGVTLYEMIAARGPFRARGEKVENKELK 405
                    T  + +PE+L   EY  SVD ++ G    E+   R  F+   E  + K++ 
Sbjct: 675 HMALTTVVVTLWYRSPEVLMQAEYGTSVDIWSCGCIFAELFTRRALFKGSSEFDQLKKIF 854

Query: 406 QRIISEPV-KYPEKFSQASKDF-------CEQLL-EKDP------EKRLGFRDGTCDALR 450
           + I   P   +PE  S     F        + L+ E DP      EK L F+ G   + R
Sbjct: 855 EVIGLPPAGDWPEGVSVHRNSFRPTPPVPLQTLVPEMDPQAKDLMEKMLVFKSGRRISSR 1034

Query: 451 ANVL 454
            ++L
Sbjct: 1035ESLL 1046
>17722
          Length = 680

 Score = 70.5 bits (171), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 35/108 (32%), Positives = 59/108 (54%)
 Frame = -3

Query: 373 VDYFALGVTLYEMIAARGPFRARGEKVENKELKQRIISEPVKYPEKFSQASKDFCEQLLE 432
           VD++  GV +YEM+  R PF  R   V    L + I+ + VK+P   S+ +K     LL 
Sbjct: 678 VDWWGTGVVMYEMMCGRLPFYNRDHDV----LFELILLQNVKFPRNLSEEAKTLLSGLLA 511

Query: 433 KDPEKRLGFRDGTCDALRANVLFKDISWRQLEAGMLIPPFIPDSRTVY 480
           K+P++RLG  +     ++ +  F+ I+W  L A  + PP+ PD ++ +
Sbjct: 510 KNPKRRLGGSEADVTEIKTHPFFQCINWDDLAAKKITPPWKPDVKSSW 367
>01718
          Length = 959

 Score = 70.5 bits (171), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 66/250 (26%), Positives = 115/250 (46%), Gaps = 7/250 (2%)
 Frame = +3

Query: 196 LGKGGFGEVSACQMKATGKMYACXXXXXXXXXXXXGYQGAIVEKRILTKVHSRFIVSLAY 255
           +G G F EV     + TG++ A                  + E ++L ++    I+    
Sbjct: 171 IGAGFFSEVFKVTHRITGQVMA-----LKMNTMTSNRHNMLREVQLLNRLQHANILRFMG 335

Query: 256 AFETKTDLCLVMTIMNGGDVRYHIYNVDEDNPGFSEPRAIYYTAQIISGLEHLHQRRIVY 315
               +  L  +   +  G++   +   DE+ P     + I  T  +  GL++LH  R ++
Sbjct: 336 VCVHEGQLHALTEYIPSGNLEQLLEKKDEELPW---TQRIQLTLGLARGLDYLHSTRFIH 506

Query: 316 RDLKPENVLL---DNDG-NIRISDLGLAVELKEGQNKTK-GYAGTPGFMAPELLRGEEYD 370
           RDL  +N+L+   DN G +  I+D GLA ++ +  +K K    G+P +MAPE+L G  Y+
Sbjct: 507 RDLTSKNILIRREDNHGYHAVIADFGLATKIPDPLDKEKLPTVGSPYWMAPEVLNGHFYN 686

Query: 371 FSVDYFALGVTLYEMIAARGPFRAR-GEKVENKELKQRIISEPVKY-PEKFSQASKDFCE 428
              D F++G+ + E I AR P       ++ N  +    +SE + Y P  + Q +   C 
Sbjct: 687 ERADLFSVGIIMCE-ITARIPADPDIMPRMNNFGVDYVALSEMISYCPLDYLQLAFKCC- 860

Query: 429 QLLEKDPEKR 438
              + DP+KR
Sbjct: 861 ---QVDPQKR 881
>21433
          Length = 590

 Score = 68.9 bits (167), Expect = 5e-12,   Method: Compositional matrix adjust.
 Identities = 36/100 (36%), Positives = 60/100 (60%)
 Frame = +2

Query: 293 RAIYYTAQIISGLEHLHQRRIVYRDLKPENVLLDNDGNIRISDLGLAVELKEGQNKTKGY 352
           R   Y  Q+ S LE+ H R++++RD+KPEN+LL   G+++I+D G +V     +  T   
Sbjct: 170 RTACYIYQLSSALEYCHYRKVIHRDIKPENLLLGLKGDLKIADFGWSVHAPSSRRTTM-- 343

Query: 353 AGTPGFMAPELLRGEEYDFSVDYFALGVTLYEMIAARGPF 392
            GT  ++ PE++ G+ +D +VD ++LGV  YE +    P 
Sbjct: 344 CGTLDYLPPEMVEGKTHDENVDLWSLGVLCYEFLVGTPPL 463
>25019
          Length = 730

 Score = 55.5 bits (132), Expect(2) = 1e-11,   Method: Compositional matrix adjust.
 Identities = 25/59 (42%), Positives = 38/59 (64%)
 Frame = +3

Query: 321 ENVLLDNDGNIRISDLGLAVELKEGQNKTKGYAGTPGFMAPELLRGEEYDFSVDYFALG 379
           ENVLLD DG+++++D GL  E   G   T  + GT  +MAPE+L    +  +VD+++LG
Sbjct: 261 ENVLLDKDGHVKLTDFGLCKEAITGTRVTHTFCGTIEYMAPEILTRTGHGKAVDWWSLG 437

 Score = 32.0 bits (71), Expect(2) = 1e-11,   Method: Compositional matrix adjust.
 Identities = 16/62 (25%), Positives = 30/62 (48%)
 Frame = +1

Query: 379 GVTLYEMIAARGPFRARGEKVENKELKQRIISEPVKYPEKFSQASKDFCEQLLEKDPEKR 438
           G  +Y+M+    PF A   K    +   +I+   +  P   +  ++   ++LL K+P +R
Sbjct: 436 GALMYDMLTGSPPFTAENRK----KTIDKILKGKLNLPPYLTNEARGLIKKLLRKNPAER 603

Query: 439 LG 440
           LG
Sbjct: 604 LG 609
>01392
          Length = 1806

 Score = 66.6 bits (161), Expect = 3e-11,   Method: Compositional matrix adjust.
 Identities = 54/183 (29%), Positives = 79/183 (43%), Gaps = 28/183 (15%)
 Frame = -1

Query: 289  FSEPRAIYYTAQIISGLEHLHQRRIVYRDLKPENVL---LDNDGNIRISDLGLAVELKEG 345
              E  A      I   L+ LH + I +RDLKPEN+L   LD+   ++I D  LA  +   
Sbjct: 1800 LCEREASLVVRHIARALDFLHSKGIAHRDLKPENILCEHLDDVVPVKICDFDLASGISCD 1621

Query: 346  QNKTK-----GYAGTPGFMAPELLRGE-----EYDFSVDYFALGVTLYEMIAARGPFRA- 394
             + TK        G+  +MAPE++         YD   D ++LG+ LY M+    PF   
Sbjct: 1620 GDGTKTPELLTPVGSAEYMAPEVVDAWVGDSFSYDKRCDLWSLGIILYIMLCGYPPFYGQ 1441

Query: 395  --------RGEKVENKE--LKQRIISEPVKYPEK----FSQASKDFCEQLLEKDPEKRLG 440
                    RGE   + +  L   I     K+P +     S ++KD    LL ++P KR  
Sbjct: 1440 CGEDCGWNRGEACHDCQDMLFNSIQDGHYKFPSQEWTSISSSAKDLIRHLLVREPRKRYS 1261

Query: 441  FRD 443
              D
Sbjct: 1260 AAD 1252
>00715
          Length = 1788

 Score = 66.2 bits (160), Expect = 3e-11,   Method: Compositional matrix adjust.
 Identities = 43/137 (31%), Positives = 66/137 (48%), Gaps = 22/137 (16%)
 Frame = +1

Query: 300 QIISGLEHLHQRRIVYRDLKPENVLLDNDGNIRISDLGLA-------------------- 339
           Q+  GL +LH   IV+ DLKP N LL  D  +RI+D G                      
Sbjct: 262 QMARGLHYLHSINIVHLDLKPANCLLTRDLKLRIADFGCCHQLTPTGLDMGEREGGMAGN 441

Query: 340 -VELKEGQNKTKG-YAGTPGFMAPELLRGEEYDFSVDYFALGVTLYEMIAARGPFRARGE 397
            +EL   Q   K   AGT  + APELL+G +     D ++LG+TL++M   +GP+    E
Sbjct: 442 ELELTPVQGAWKNELAGTLAYRAPELLKGLQPSVRSDVYSLGITLWQMCTRQGPY----E 609

Query: 398 KVENKELKQRIISEPVK 414
            V    +  +++S+ ++
Sbjct: 610 GVPAHAVVYQVVSKDLR 660
>16708
          Length = 1397

 Score = 65.9 bits (159), Expect = 4e-11,   Method: Compositional matrix adjust.
 Identities = 71/268 (26%), Positives = 102/268 (38%), Gaps = 20/268 (7%)
 Frame = -1

Query: 193  FRVLGKGGFGEVSACQMKATGKMYACXXXXXXXXXX-XXGYQGAIVEKRILTKVHSRFIV 251
             +VLGKG FG+V   ++ +T +  A                 G I     L ++   ++ 
Sbjct: 1388 LQVLGKGVFGKVYEARLLSTHEKAALKTSILCHHSLDEVEALGRIEGGFYLAQMFGAWVT 1209

Query: 252  SLAYAFETKTDLCLVMTIMNGGDVRYHIYNVDEDNPGFSEPRAIYYTA-QIISGLEHLHQ 310
             L +    K ++ L    M      Y  Y   E    +S P  +   A Q +  LEH+H+
Sbjct: 1208 CLPFP---KMNILLHFYEMGPLCNVYAHYKNKEMPIRWSNPAMVCCIAGQXVCALEHIHE 1038

Query: 311  RRIVYRDLKPENVLLDNDGNIRISDLGLA-----------VELKEGQNKTKGYAGTPGFM 359
              +V+ D+K +NVL+D  GN +++D G+A                  NK   Y   P  M
Sbjct: 1037 LGVVHMDVKADNVLVDAHGNCKLTDYGIAQLYKVYPAPTETHSSGCTNKRTFYTRPPATM 858

Query: 360  APELLRGEEYD-FSVDYFALGVTLYEMIAARGPFRARGEKVENKELKQRIISEPVKY--- 415
             P     EE D    DYF LG  L+ +  A               L    +S P K    
Sbjct: 857  TPSERFSEEGDGIGTDYFRLGQMLWTLTGA--------------VLLHVWVSRPPKLPDW 720

Query: 416  ---PEKFSQASKDFCEQLLEKDPEKRLG 440
               PE       DF E+L   DP  RLG
Sbjct: 719  CRTPESELSGMSDFIEKLCHGDPNMRLG 636
>11185
          Length = 473

 Score = 64.7 bits (156), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 43/167 (25%), Positives = 72/167 (43%), Gaps = 22/167 (13%)
 Frame = +1

Query: 297 YTAQIISGLEHLHQRRIVYRDLKPENVLLDNDGNIRISDLGLA----------------- 339
           +   +++GL ++H   I++ DL+P  VLLD  G ++ +D GL+                 
Sbjct: 16  FGIHLVTGLHYIHSLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEA 195

Query: 340 -----VELKEGQNKTKGYAGTPGFMAPELLRGEEYDFSVDYFALGVTLYEMIAARGPFRA 394
                ++  E   K    +G+P +MAPE+ +G E     D +ALG   YEM +       
Sbjct: 196 GDQWNIQSAEEMMKQVPTSGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFSG------ 357

Query: 395 RGEKVENKELKQRIISEPVKYPEKFSQASKDFCEQLLEKDPEKRLGF 441
                       R+ ++P   PE       +  E LL+KD  +RL +
Sbjct: 358 -----------SRLSAKPS--PEFL-----NLLESLLQKDSTRRLSW 444
>26711
          Length = 405

 Score = 63.9 bits (154), Expect = 2e-10,   Method: Composition-based stats.
 Identities = 34/97 (35%), Positives = 58/97 (59%), Gaps = 2/97 (2%)
 Frame = -2

Query: 300 QIISGLEHLHQRRIVYRDLKPENVLLDND--GNIRISDLGLAVELKEGQNKTKGYAGTPG 357
           Q++  L+H+H + +V+ DLKP N+LL  D   ++++ D GLA +L   Q     + GTPG
Sbjct: 392 QVLDILQHVHAQGVVHMDLKPSNLLLSGDKLDSVQLIDFGLARKLYPPQETFLNH-GTPG 216

Query: 358 FMAPELLRGEEYDFSVDYFALGVTLYEMIAARGPFRA 394
           F +PE L  +    + D + +GV  Y +++ + PF+A
Sbjct: 215 FTSPEALDVKPISTASDVWGVGVLAYILLSGQSPFQA 105
>00486
          Length = 797

 Score = 63.9 bits (154), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 34/127 (26%), Positives = 63/127 (49%)
 Frame = -2

Query: 349 TKGYAGTPGFMAPELLRGEEYDFSVDYFALGVTLYEMIAARGPFRARGEKVENKELKQRI 408
           T  + GT  +MAPE+L    +  +VD+++LG  +Y+M+    PF A       K+   +I
Sbjct: 787 THTFCGTIEYMAPEILTRTGHGKAVDWWSLGALMYDMLTGSPPFTAENR----KKTIDKI 620

Query: 409 ISEPVKYPEKFSQASKDFCEQLLEKDPEKRLGFRDGTCDALRANVLFKDISWRQLEAGML 468
           +   +  P   +  ++   ++LL K+P +RLG        ++ +  F++ +W  L     
Sbjct: 619 LKGKLNLPPYLTNEARGLIKKLLRKNPAERLGGGHDDSGPIKDHQFFRNTNWALLALRRA 440

Query: 469 IPPFIPD 475
            PPF P+
Sbjct: 439 EPPFRPN 419
>01966
          Length = 1735

 Score = 62.8 bits (151), Expect = 4e-10,   Method: Compositional matrix adjust.
 Identities = 29/72 (40%), Positives = 44/72 (61%)
 Frame = -1

Query: 297  YTAQIISGLEHLHQRRIVYRDLKPENVLLDNDGNIRISDLGLAVELKEGQNKTKGYAGTP 356
            Y  QI++G+   HQRRIV+RDLKP+N+L+++ G I+I+D G+A               T 
Sbjct: 1393 YVFQIVTGINFCHQRRIVHRDLKPQNLLINHTGAIKIADFGMARTFALPVRAYTHEVVTL 1214

Query: 357  GFMAPELLRGEE 368
             + APE+L G +
Sbjct: 1213 WYRAPEILMGPQ 1178
>29581
          Length = 1278

 Score = 62.8 bits (151), Expect = 4e-10,   Method: Compositional matrix adjust.
 Identities = 37/125 (29%), Positives = 66/125 (52%), Gaps = 1/125 (0%)
 Frame = -2

Query: 289  FSEPRAIYYTAQIISGLEHLHQRRIVYRDLKPENVLLDNDGNIRISDLGLAVELKEGQNK 348
            FSE +      Q++ GL +LH+  I++RDLK  N+L+ + G ++I+D GLA    + Q  
Sbjct: 1058 FSESQVKCIVLQLLKGLRYLHEAFIIHRDLKVSNLLMTDKGCVKIADFGLARNYGKPQKP 879

Query: 349  TKGYAGTPGFMAPELLRGEE-YDFSVDYFALGVTLYEMIAARGPFRARGEKVENKELKQR 407
                  T  + APELL G + +  ++D ++ G  L E++  +     R + ++  EL   
Sbjct: 878  MTPKVVTLWYRAPELLFGSKTHSTAIDMWSAGCILGELLGHKPLMPGRSD-LQQIELIME 702

Query: 408  IISEP 412
            ++  P
Sbjct: 701  LLGTP 687
>09007
          Length = 1440

 Score = 61.6 bits (148), Expect = 9e-10,   Method: Compositional matrix adjust.
 Identities = 53/211 (25%), Positives = 90/211 (42%), Gaps = 9/211 (4%)
 Frame = -1

Query: 183 QPIGEDWFLDFRVLGKGGFGEV-SACQMKATGKMYACXXXXXXXXXXXXGYQGAIVEKRI 241
           Q I +D     + LG+G FG V  A     +G+                  Q  + E  I
Sbjct: 894 QLISKDCVALSKSLGQGHFGTVRQAIWTAESGEKVQVAVKCLSKDKIHKDGQEFLKETAI 715

Query: 242 LTKV-HSRFIVSLAYAFETKTDLCLVMTIMNGGDVRYHIYNVDEDNP--GFSEPRAIYYT 298
           +  + H   +       +   D+ LV  +     +R  +  V E +    FS PR   ++
Sbjct: 714 MQMLDHENIVRVYGVVMDNGADIMLVTEL---APMRSLLECVKEVSARVDFSVPRLCDFS 544

Query: 299 AQIISGLEHLHQRRIVYRDLKPENVLLDNDGNIRISDLGLAVELKEGQ-----NKTKGYA 353
            Q+  G+ +L  +R+V+RDL   N+LL +   ++ISD+G++  L  G+      +T    
Sbjct: 543 QQVCDGMSYLESKRLVHRDLAARNILLFSKSKVKISDVGVSGALGAGKEYYQSQQTIHLQ 364

Query: 354 GTPGFMAPELLRGEEYDFSVDYFALGVTLYE 384
               + APE  R   +  + D +A GV L+E
Sbjct: 363 NAVAWCAPESFRNLCFSSASDVWAFGVLLWE 271
>14116
          Length = 1017

 Score = 60.8 bits (146), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 53/199 (26%), Positives = 89/199 (44%), Gaps = 7/199 (3%)
 Frame = -1

Query: 196 LGKGGFGEVSACQM---KATGKMYACXXXXXXXXXXXXGYQGAIVEKRILTKVHSRFIVS 252
           +GKG FG V    +   +  G +                 Q  + E  I+   H   +++
Sbjct: 612 IGKGNFGCVKRGFLTLPEQKGDILVAVKTLHNNNPREIELQSFLQEALIMKDFHHSNVLT 433

Query: 253 LAYAFETKTDLCLV-MTIMNGGDVRYHIYNVDEDNPGFSEPRAIYYTAQIISGLEHLHQR 311
           L        D+ LV +  M  GD+  +I + D+  P   +   I Y   I  G+++L   
Sbjct: 432 LIGICLNLDDMPLVVLPFMKHGDLLTYIRD-DQHQPTIKD--LIMYGVDIARGMDYLAGL 262

Query: 312 RIVYRDLKPENVLLDNDGNIRISDLGLAVEL--KEGQNKTKGYAGTP-GFMAPELLRGEE 368
           + V+RDL   N +LD D +++++D GLA ++  KE  +     A  P  +MA E L    
Sbjct: 261 KFVHRDLAARNCMLDEDFHVKVADFGLARDIYEKEYYSSENKKAKLPVKWMALESLEKGN 82

Query: 369 YDFSVDYFALGVTLYEMIA 387
           YD   D ++ GV L+E++ 
Sbjct: 81  YDSKTDVWSYGVVLWELLT 25
>13066
          Length = 551

 Score = 59.7 bits (143), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 43/147 (29%), Positives = 74/147 (50%), Gaps = 5/147 (3%)
 Frame = +3

Query: 238 EKRILTKVHSRFIVSLAYAFETKTDLCLVMTIMNGGDVRYHIYNVDEDNPGF-SEPRAIY 296
           E  +LTK+   +I+ +    +      + M     GD+  +I  V     GF  E +A  
Sbjct: 126 ELDLLTKLDHPYIIQIHSILQRXPKNFIFMRFAERGDLLTYIQEV-----GFVKEKQAKI 290

Query: 297 YTAQIISGLEHLHQRRIVYRDLKPENVLLDNDGNIRISDLGLAVE-LKEGQNK--TKGYA 353
           +  Q+ + L +LH   + +RDLK EN+LL +  N++++D G A   + E   K  ++ Y 
Sbjct: 291 WFYQMTTALNYLHSYDVAHRDLKCENILLSSHFNVKLADFGFACACITESGEKYMSRTYC 470

Query: 354 GTPGFMAPELLRGEEYDFSV-DYFALG 379
           G+  + APE++ G  Y   V D ++LG
Sbjct: 471 GSAAYAAPEIVYGAPYAPKVADAWSLG 551
>04591
          Length = 1117

 Score = 59.7 bits (143), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 32/101 (31%), Positives = 60/101 (59%), Gaps = 1/101 (0%)
 Frame = -2

Query: 299 AQIISGLEHLHQRRIVYRDLKPENVLLDNDGNIRISDLGLAVELKEGQNKTKGYAGTPGF 358
           +Q+++GL ++H ++I++RD+K  N+LL  DG ++++D GL+    + +  T     T  +
Sbjct: 876 SQLLNGLFYIHTKQILHRDIKAANILLTRDGVLKLADFGLSRPWVKSKRLTNRVV-TLWY 700

Query: 359 MAPELLRGE-EYDFSVDYFALGVTLYEMIAARGPFRARGEK 398
             PELL GE EY   +D + +G  + EM + +   + R E+
Sbjct: 699 RPPELLLGEREYGPEIDMWGVGCIMAEMWSRKPLMQGRSEQ 577
>26156
          Length = 479

 Score = 45.4 bits (106), Expect(2) = 4e-09,   Method: Compositional matrix adjust.
 Identities = 25/91 (27%), Positives = 44/91 (48%), Gaps = 1/91 (1%)
 Frame = -1

Query: 190 FLDFRVLGKGGFGEVSACQMKATGKMYACXXXXXXXXXXXXGYQGAIVEKRIL-TKVHSR 248
           FL  RV+G+G + +V   + K T ++YA                    EK +  T  +  
Sbjct: 383 FLLLRVIGRGSYAKVLQVEHKRTKRIYAMKVIKKELVNDDEDIDWVQTEKHVFETATNYP 204

Query: 249 FIVSLAYAFETKTDLCLVMTIMNGGDVRYHI 279
           F+V L   F++++ L  V+  +NGGD+ +H+
Sbjct: 203 FLVGLHSCFQSESRLFFVIEFVNGGDLMFHM 111

 Score = 33.9 bits (76), Expect(2) = 4e-09,   Method: Composition-based stats.
 Identities = 14/24 (58%), Positives = 18/24 (75%)
 Frame = -3

Query: 296 YYTAQIISGLEHLHQRRIVYRDLK 319
           +Y+A+I   L  LH+R IVYRDLK
Sbjct: 75  FYSAEICLALNFLHKRGIVYRDLK 4
>12672
          Length = 773

 Score = 58.2 bits (139), Expect = 9e-09,   Method: Compositional matrix adjust.
 Identities = 54/181 (29%), Positives = 81/181 (44%), Gaps = 6/181 (3%)
 Frame = +3

Query: 303 SGLEHLHQRRIVYRDLKPENVLLDNDGNIRISDLGLAVELKEGQNKTKGYA----GTPGF 358
           SG+++L+    V+RD+K  N+LLD++   ++ D    V    G+ KT   A    GT  +
Sbjct: 24  SGIQYLNDNGHVHRDIKTANILLDSEYTAKVGDFATVVSAPSGEGKTVQNASVVIGTAAY 203

Query: 359 MAPELLRGEEYDFS--VDYFALGVTLYEMIAARGPFRARGEKVENKELKQRIISEPVKYP 416
           +APE +    +D S  +D ++ GV L E+I       A+    E + L   I+ E V+ P
Sbjct: 204 LAPEAIH---FDVSTKLDSYSFGVVLLEVITG---LVAQDYSREERTLSSHIM-ENVEEP 362

Query: 417 EKFSQASKDFCEQLLEKDPEKRLGFRDGTCDALRANVLFKDISWRQLEAGMLIPPFIPDS 476
           E+      DF +Q     P       DG  D L       DIS R L       P + D 
Sbjct: 363 EEI----HDFVDQSAGTWP-------DGAVDKLY------DISMRCLNLSKKQRPNVKDI 491

Query: 477 R 477
           R
Sbjct: 492 R 494
>17975
          Length = 449

 Score = 57.0 bits (136), Expect = 2e-08,   Method: Composition-based stats.
 Identities = 33/110 (30%), Positives = 59/110 (53%), Gaps = 1/110 (0%)
 Frame = +3

Query: 238 EKRILTKVHSRFIVSLAYAFETKTDLCLVMTIMNGGDVRYHIYNVDEDNPGFSEPRAIYY 297
           E R +  V    +V L    +T+T L L++ + +GGD+  +I      + G  E  A  Y
Sbjct: 114 EVRCMKLVQHPNVVRLYEVIDTQTKLYLILELGDGGDMYDYIM---RHSGGLEEKLAKRY 284

Query: 298 TAQIISGLEHLHQRRIVYRDLKPENVL-LDNDGNIRISDLGLAVELKEGQ 346
             QI+  + + H+  +V+RDLKPENV+  +  G ++++D G +  L + +
Sbjct: 285 FRQIVEAISYCHKLHVVHRDLKPENVVFFEKPGLVKLTDFGFSTCLLQAK 434
>04852
          Length = 1462

 Score = 56.6 bits (135), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 36/122 (29%), Positives = 62/122 (50%), Gaps = 1/122 (0%)
 Frame = +1

Query: 297 YTAQIISGLEHLHQRRIVYRDLKPENVLLDNDGNIRISDLGLAVELKEGQNKTKGYAGTP 356
           Y  QI  G+E L  R+ ++RDL   NVL+  +  ++I+D GL+    +   K  G     
Sbjct: 340 YAFQIARGMEFLASRKCIHRDLAARNVLVTEEHVLKIADFGLS-RTGDYYKKRSGGRLPV 516

Query: 357 GFMAPELLRGEEYDFSVDYFALGVTLYEMIAARG-PFRARGEKVENKELKQRIISEPVKY 415
            +MAPE L    Y    D ++ GV L+E+ +  G P+ +    + N+EL  +++ +  + 
Sbjct: 517 KWMAPEALFDMRYTTKSDVWSFGVVLWEIFSLGGMPYAS----IPNEELYSKLLDDAYRM 684

Query: 416 PE 417
           P 
Sbjct: 685 PR 690
>01756
          Length = 1858

 Score = 56.6 bits (135), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 51/205 (24%), Positives = 93/205 (45%), Gaps = 15/205 (7%)
 Frame = -3

Query: 196  LGKGGFGEVSACQMKATGKMYACXXXXXXXXXXXXGYQ-GAIVEKRILTKVHSRFIVSLA 254
            +G+G FGEV   + K T ++ A             G+   A+ E +IL  ++   +V L 
Sbjct: 1718 IGQGTFGEVFKARCKKTKQVVA--MKKVLMDNEKEGFPITALREIKILQLLNHENVVDLI 1545

Query: 255  YAFETKTDLCLVMTIMNGGDVRYHIYNVDEDNPG---------FSEPRAIYYTAQIISGL 305
                TK       +      + Y ++   E +           F+ P       Q+++GL
Sbjct: 1544 EICSTKAT-----SANRYKSMFYLVFEFCEHDLAGLLSNMSVVFNLPEIKEVMKQLMNGL 1380

Query: 306  EHLHQRRIVYRDLKPENVLLDNDGNIRISDLGLA----VELKEGQNKTKGYAGTPGFMAP 361
             ++H+ +I++RD+K  N+L+   G ++++D GLA    V L++  N+      T  +  P
Sbjct: 1379 YYIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQP-NRYTNRVVTLWYRPP 1203

Query: 362  ELLRGE-EYDFSVDYFALGVTLYEM 385
            ELL G+  Y  ++D +  G  + EM
Sbjct: 1202 ELLLGDRNYSTAIDQWGAGCIMAEM 1128
>21808
          Length = 1011

 Score = 55.1 bits (131), Expect = 8e-08,   Method: Compositional matrix adjust.
 Identities = 41/160 (25%), Positives = 77/160 (48%), Gaps = 3/160 (1%)
 Frame = +1

Query: 236 IVEKRILTKVHSRFIVSLAYAFETKTDLCLVMT-IMNGGDVRYHIYNVDEDNPGFSEPRA 294
           + E +I+ K+    ++ L YA  T+ D   ++T +M  G +   +  +         P  
Sbjct: 76  LAEAQIMKKLRHPKLIQL-YAVCTQDDPIFIITELMKNGSL---LEFLQGKGRVLKLPAL 243

Query: 295 IYYTAQIISGLEHLHQRRIVYRDLKPENVLLDNDGNIRISDLGLAVELKEGQNKTKGYAG 354
           I   AQI  G+ +L  +  ++RDL   N+L+ ++  ++I+D GLA  +KE + + +  A 
Sbjct: 244 IDIGAQIACGMAYLESQNYIHRDLAARNILVSDNNTVKIADFGLARVIKEDEYEARVGAR 423

Query: 355 TP-GFMAPELLRGEEYDFSVDYFALGVTLYEMIA-ARGPF 392
            P  + APE      +    D ++ G+ L E +   R P+
Sbjct: 424 FPIKWTAPEAANYNRFTIKSDVWSFGILLTETVTYGRVPY 543
>28638
          Length = 1458

 Score = 53.9 bits (128), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 31/85 (36%), Positives = 47/85 (55%), Gaps = 2/85 (2%)
 Frame = -1

Query: 310 QRRIVYRDLKPENVLLDND--GNIRISDLGLAVELKEGQNKTKGYAGTPGFMAPELLRGE 367
           +  I++ DLKPEN+LL N     I+I D G + +L  GQ +   Y  +  + +PE+L G 
Sbjct: 777 EMNIIHCDLKPENILLCNPKRSAIKIVDFGSSCQL--GQ-RIYQYIQSRFYRSPEVLLGV 607

Query: 368 EYDFSVDYFALGVTLYEMIAARGPF 392
            YD ++D ++LG  L EM     P 
Sbjct: 606 PYDLAIDMWSLGCILVEMHTGEPPL 532
>03508
          Length = 1463

 Score = 53.9 bits (128), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 37/122 (30%), Positives = 62/122 (50%), Gaps = 4/122 (3%)
 Frame = +1

Query: 278 HIYNVD--EDNPGFSEPRAIYYTAQIISGLEHLHQRRIVYRDLKPENVLLDNDG-NIRIS 334
           H+ N D  +    F++    +Y  +++  L+  H   I++RD+KP NV++D++   +R+ 
Sbjct: 823 HVNNTDFKQLYQTFTDYDIRFYLYELMKALDFCHSMGIMHRDVKPHNVMIDHENKKLRLI 1002

Query: 335 DLGLAVELKEGQNKTKGYAGTPGFMAPELLRGEE-YDFSVDYFALGVTLYEMIAARGPFR 393
           D GLA     G       A +  F  PELL   + YD+S+D ++LG     MI  + P  
Sbjct: 1003DWGLAEFYHPGMEYNVRVA-SRYFKGPELLLDYQMYDYSLDMWSLGCMFASMIFRKEPLL 1179

Query: 394 AR 395
            R
Sbjct: 1180PR 1185
>06405
          Length = 1965

 Score = 53.9 bits (128), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 47/192 (24%), Positives = 82/192 (42%), Gaps = 2/192 (1%)
 Frame = +1

Query: 196 LGKGGFGEVSACQMKATGKMYACXXXXXXXXXXXXGYQGAIVEKRILTKVHSRFIVSLAY 255
           LG G +G+V     K   K+ A                  + E  I+ ++    +V L  
Sbjct: 283 LGGGQYGDVYEAMWKRYNKIVAVKTLKEDTM----ALNDFLEEAAIMKEMKHPNLVQLLG 450

Query: 256 AFETKTDLCLVMTIMNGGDVRYHIYNVDEDNPGFSEPRAIYYTA-QIISGLEHLHQRRIV 314
               +    +V   M  G++  ++ +   +  G   P A+ Y A QI SG+ +L  +  +
Sbjct: 451 VCTREPPFYIVTEFMPHGNLLDYLRSSTREENG---PTALMYMATQIASGMAYLETKNFI 621

Query: 315 YRDLKPENVLLDNDGNIRISDLGLAVELKEGQNKTKGYAGTP-GFMAPELLRGEEYDFSV 373
           +RDL   N L+ +   ++++D GLA  +K+        A  P  + APE L    +    
Sbjct: 622 HRDLAARNCLVADSNMVKVADFGLARLMKDDTYTAHIGAKFPIKWTAPEGLAFNRFSTRS 801

Query: 374 DYFALGVTLYEM 385
           D +A GV L+E+
Sbjct: 802 DIWAFGVLLWEL 837
>02638
          Length = 1490

 Score = 53.5 bits (127), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 31/92 (33%), Positives = 48/92 (52%), Gaps = 2/92 (2%)
 Frame = +1

Query: 354 GTPGFMAPELLRGEEYDFSVDYFALGVTLYEMIAARGPFRARGEKVENKELKQRIIS--E 411
           GT  FMAPE+LRGE Y  + D +++G  + EM   R P+ +  +   +  L  +I S  +
Sbjct: 22  GTIAFMAPEVLRGESYGRACDVWSVGCVMIEMCTCRPPWNSH-DISNHLALIFKIASSVD 198

Query: 412 PVKYPEKFSQASKDFCEQLLEKDPEKRLGFRD 443
           P   PE  S   +D   + LE+D + R   +D
Sbjct: 199 PPPIPENMSPPVRDLMLRCLEQDSDFRPSAKD 294
>07940
          Length = 1336

 Score = 51.6 bits (122), Expect = 8e-07,   Method: Compositional matrix adjust.
 Identities = 31/98 (31%), Positives = 51/98 (52%), Gaps = 2/98 (2%)
 Frame = -3

Query: 295 IYYTAQIISGLEHLHQRRIVYRDLKPENVLLDNDGNIRISDLGLAVELKEGQNKTKGYAG 354
           I Y  Q+  G+E+L  ++ ++RDL   NVL+  +  ++I+D GL   L++     K   G
Sbjct: 338 ISYAYQVARGMEYLASKQCIHRDLAARNVLVAEEYVLKIADFGLTRNLQQFDYYRKTTDG 159

Query: 355 T--PGFMAPELLRGEEYDFSVDYFALGVTLYEMIAARG 390
                +MAPE L   +Y    D ++ GV L+E+    G
Sbjct: 158 RLPVKWMAPEALFDRKYTSKSDVWSYGVLLWEIFTLGG 45
>07836
          Length = 1478

 Score = 51.6 bits (122), Expect = 8e-07,   Method: Compositional matrix adjust.
 Identities = 38/114 (33%), Positives = 58/114 (50%), Gaps = 18/114 (15%)
 Frame = -1

Query: 290  SEPRAIYYTAQIISGLEHLH--------QRRIVYRDLKPENVLLDNDGNIRISDLGLAVE 341
            SE  A+ ++A  I GL HLH        +  I +RD+K +N+L+  +G   I+DLGLAV 
Sbjct: 1256 SEMLALAHSA--ICGLAHLHIEIFGTRGKPAIAHRDIKSKNILVKKNGTCCIADLGLAVR 1083

Query: 342  LKEGQNKT----KGYAGTPGFMAPE----LLRGEEYDF--SVDYFALGVTLYEM 385
                 N+         GT  +MAPE    LL  + +D     D +A G+ ++E+
Sbjct: 1082 YISESNEVDVAPNPRQGTKRYMAPEVLEMLLNVKNFDAFKQADMYAFGLVMWEI 921
>19301
          Length = 712

 Score = 49.7 bits (117), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 29/100 (29%), Positives = 48/100 (48%)
 Frame = +2

Query: 240 RILTKVHSRFIVSLAYAFETKTDLCLVMTIMNGGDVRYHIYNVDEDNPGFSEPRAIYYTA 299
           R L K++   I+S           C++M     G     +Y V  D         + ++ 
Sbjct: 425 RNLRKLNHPNIISFKGVCTQAPCYCIIMEYCPYG----QLYEVLRDGKEIPPALVLDWSK 592

Query: 300 QIISGLEHLHQRRIVYRDLKPENVLLDNDGNIRISDLGLA 339
           QI SG+ +LH  +I++RDLK  NVL+  +  ++ISD G +
Sbjct: 593 QIASGMNYLHSHKIIHRDLKSPNVLVAKNDVVKISDFGTS 712
>04138
          Length = 800

 Score = 48.9 bits (115), Expect = 6e-06,   Method: Compositional matrix adjust.
 Identities = 27/86 (31%), Positives = 49/86 (56%), Gaps = 5/86 (5%)
 Frame = +1

Query: 305 LEHLHQRRIVYRDLKPENVLLDNDGNIRISDLGLA----VELKEGQNKTKGYAGTPGFMA 360
           L ++H+ +I++RD+K  N+L+   G ++++D GLA    V L++  N+      T  +  
Sbjct: 52  LYYIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQ-PNRYTNRVVTLWYRP 228

Query: 361 PELLRGE-EYDFSVDYFALGVTLYEM 385
           PELL G+  Y  ++D +  G  + EM
Sbjct: 229 PELLLGDRNYSTAIDQWGAGCIMAEM 306
>28157
          Length = 400

 Score = 47.8 bits (112), Expect = 1e-05,   Method: Composition-based stats.
 Identities = 34/109 (31%), Positives = 57/109 (52%), Gaps = 4/109 (3%)
 Frame = +3

Query: 238 EKRILTKVHSRFIVSLAYAFETKTDLCLVMTIMNGGDVRYHIYNVDEDNPGFSEPRAIYY 297
           E + L++V    IV L Y       +CLVM    GG + Y++ +     P ++   A+ +
Sbjct: 60  ELKQLSRVSHPNIVCL-YGACRDHPVCLVMEYAEGGSL-YNVLHGSGPQPQYTAAHAMNW 233

Query: 298 TAQIISGLEHLH---QRRIVYRDLKPENVLLDNDGN-IRISDLGLAVEL 342
             Q   G+E+LH    + +++RDLKP N+LL   G  ++I D G A ++
Sbjct: 234 LLQCALGVEYLHGMKPKALIHRDLKPPNLLLIQCGTKLKICDFGTACDI 380
>27546
          Length = 426

 Score = 47.4 bits (111), Expect = 2e-05,   Method: Composition-based stats.
 Identities = 30/102 (29%), Positives = 49/102 (48%)
 Frame = -1

Query: 238 EKRILTKVHSRFIVSLAYAFETKTDLCLVMTIMNGGDVRYHIYNVDEDNPGFSEPRAIYY 297
           E  ILT++    I+ +    +    + + M     GD+  HI    +  P   E +   +
Sbjct: 330 ELEILTRLDHPNIIQIHSILQRGPKIFIFMRYAEKGDMLSHI---KKTGP-IDEAQTKVW 163

Query: 298 TAQIISGLEHLHQRRIVYRDLKPENVLLDNDGNIRISDLGLA 339
             Q+   L++LH   I +RDLK EN+LL    N++I+D G A
Sbjct: 162 FFQMAKALQYLHSHDIAHRDLKCENILLSKRLNVKIADFGFA 37
>29590
          Length = 320

 Score = 41.6 bits (96), Expect(2) = 2e-05,   Method: Composition-based stats.
 Identities = 22/58 (37%), Positives = 31/58 (53%)
 Frame = +3

Query: 335 DLGLAVELKEGQNKTKGYAGTPGFMAPELLRGEEYDFSVDYFALGVTLYEMIAARGPF 392
           DLG A     G++  +   GTP ++APE+L  E      D ++LGV  Y M+ A  PF
Sbjct: 6   DLGFACLTNTGED-IRDIIGTPDYVAPEVLDYEPLSIQTDMWSLGVLSYVMLTACSPF 176

 Score = 24.6 bits (52), Expect(2) = 2e-05,   Method: Composition-based stats.
 Identities = 10/20 (50%), Positives = 14/20 (70%)
 Frame = +2

Query: 420 SQASKDFCEQLLEKDPEKRL 439
           S  +KDF ++LL KDP  R+
Sbjct: 257 SPHAKDFIKKLLVKDPRHRM 316
>11780
          Length = 1713

 Score = 46.6 bits (109), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 43/170 (25%), Positives = 71/170 (41%)
 Frame = +3

Query: 196 LGKGGFGEVSACQMKATGKMYACXXXXXXXXXXXXGYQGAIVEKRILTKVHSRFIVSLAY 255
           +GKG FG+V        G                 G Q  + E  ++T +    +V L  
Sbjct: 621 IGKGDFGDVYK------GMYRGQPVAIKQLKDKDRGEQSFLQEASVMTSLRHDNLVRLIG 782

Query: 256 AFETKTDLCLVMTIMNGGDVRYHIYNVDEDNPGFSEPRAIYYTAQIISGLEHLHQRRIVY 315
               +T + LV   M  G++  ++ +        ++   I +     + +E+L  +R+V+
Sbjct: 783 VVLGET-IFLVTEFMGKGNLVEYLRS--RGRSVITKKDQINFATDTCAAMEYLESKRLVH 953

Query: 316 RDLKPENVLLDNDGNIRISDLGLAVELKEGQNKTKGYAGTPGFMAPELLR 365
           RDL   NVL+ +DG  ++SD GLA   K G            + APE LR
Sbjct: 954 RDLAARNVLVHDDGKAKVSDFGLA---KFGDFSQTSVKFPIKWTAPEALR 1094
>38560
          Length = 479

 Score = 45.8 bits (107), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 28/91 (30%), Positives = 45/91 (49%), Gaps = 1/91 (1%)
 Frame = -3

Query: 353 AGTPGFMAPELLRGEEYDFS-VDYFALGVTLYEMIAARGPFRARGEKVENKELKQRIISE 411
            G+P + APEL+ G EY  S  D +++GV LY ++    PF    +  +   L Q+    
Sbjct: 402 CGSPAYAAPELISGLEYLGSEADIWSMGVLLYALLCGYLPF----DDEKXSHL*QKNQKR 235

Query: 412 PVKYPEKFSQASKDFCEQLLEKDPEKRLGFR 442
             + PE  S+ +    E +L+ DP  R+  R
Sbjct: 234 KDEVPEWLSEDTTKLLEGMLQTDPSHRITIR 142
>20152
          Length = 445

 Score = 45.4 bits (106), Expect = 6e-05,   Method: Composition-based stats.
 Identities = 24/79 (30%), Positives = 42/79 (53%), Gaps = 1/79 (1%)
 Frame = +1

Query: 361 PELLRGEEYDF-SVDYFALGVTLYEMIAARGPFRARGEKVENKELKQRIISEPVKYPEKF 419
           PE+L G+ YD  +VD ++LGV LY ++    PF    ++  + E    I+    + P   
Sbjct: 1   PEILLGDSYDAPAVDVWSLGVILYMLVVGEAPF----QEANDSETLTMIMDCRYQIPPHI 168

Query: 420 SQASKDFCEQLLEKDPEKR 438
           S   +D  E++L+++P  R
Sbjct: 169 SHKCQDLIEKMLQREPVDR 225
>37602
          Length = 804

 Score = 43.5 bits (101), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 23/81 (28%), Positives = 47/81 (58%)
 Frame = -1

Query: 256 AFETKTDLCLVMTIMNGGDVRYHIYNVDEDNPGFSEPRAIYYTAQIISGLEHLHQRRIVY 315
           ++  +  L + M    GG ++  IY+V    P  +EP+  +   + + GL +LH+R  ++
Sbjct: 315 SYLRREKLWIAMEYCGGGSMQ-DIYHVT--GP-LTEPQIAFVCRETLKGLHYLHRRGKMH 148

Query: 316 RDLKPENVLLDNDGNIRISDL 336
           RD+K  N+LL  +G+++++D 
Sbjct: 147 RDIKGANILLTEEGDVKLADF 85
>32957
          Length = 645

 Score = 42.4 bits (98), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 21/52 (40%), Positives = 34/52 (65%)
 Frame = +3

Query: 338 LAVELKEGQNKTKGYAGTPGFMAPELLRGEEYDFSVDYFALGVTLYEMIAAR 389
           L VE   G+ +T  + GT  +MAPE+   +EY   VD++ LG+ L+E++AA+
Sbjct: 9   LCVEKSGGRTRT--FCGTREYMAPEVHERKEYGKEVDWWGLGILLHELLAAQ 158
>17300
          Length = 480

 Score = 42.4 bits (98), Expect = 5e-04,   Method: Composition-based stats.
 Identities = 26/91 (28%), Positives = 49/91 (53%), Gaps = 4/91 (4%)
 Frame = +1

Query: 301 IISGLEHLHQRRIVYRDLKPENVLLDNDGNIRISDLGLAVELK----EGQNKTKGYAGTP 356
           I SG+  L     V+RDL   N+L++     +++D GL+ E++    EG   TKG     
Sbjct: 1   ISSGMGXLADMGYVHRDLAARNILVNEILVCKVADFGLSREIESDTTEGAYTTKGGKIPV 180

Query: 357 GFMAPELLRGEEYDFSVDYFALGVTLYEMIA 387
            + APE +   ++  + D ++ GV ++E+++
Sbjct: 181 RWTAPEAIAYRKFTSASDVWSFGVVMWEVMS 273
>31489
          Length = 329

 Score = 41.2 bits (95), Expect = 0.001,   Method: Composition-based stats.
 Identities = 23/63 (36%), Positives = 37/63 (58%)
 Frame = +3

Query: 262 DLCLVMTIMNGGDVRYHIYNVDEDNPGFSEPRAIYYTAQIISGLEHLHQRRIVYRDLKPE 321
           D+ +V  +M   D+   IY+   D P  +E    Y+  QI+ GL+++H   +V+RDLKP 
Sbjct: 90  DIHVVFDLMES-DLHRIIYS---DQP-LTEEHIRYFLYQILRGLKYIHSANVVHRDLKPS 254

Query: 322 NVL 324
           N+L
Sbjct: 255 NLL 263
>21210
          Length = 518

 Score = 38.9 bits (89), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 25/90 (27%), Positives = 42/90 (46%), Gaps = 4/90 (4%)
 Frame = +3

Query: 353 AGTPGFMAPELL----RGEEYDFSVDYFALGVTLYEMIAARGPFRARGEKVENKELKQRI 408
           AG   +MAPE +        YD   D ++LG+TL E+   R P+R      +  +   R 
Sbjct: 3   AGCRPYMAPERIDPRASSHGYDVRSDVWSLGITLMELATGRFPYRKWVSIFDQLQQVVRG 182

Query: 409 ISEPVKYPEKFSQASKDFCEQLLEKDPEKR 438
           ++  + +   FS    +F  + L KD ++R
Sbjct: 183 VAPCLPHDGAFSHDFVNFVNKCLTKDEKQR 272
>26009
          Length = 886

 Score = 38.9 bits (89), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 15/35 (42%), Positives = 26/35 (74%)
 Frame = +3

Query: 300 QIISGLEHLHQRRIVYRDLKPENVLLDNDGNIRIS 334
           Q++S L+ +H +++V+RD+KPENVL+      R+S
Sbjct: 735 QLVSALDFMHSKQLVHRDIKPENVLILTPDFSRVS 839
>14477
          Length = 493

 Score = 38.1 bits (87), Expect = 0.010,   Method: Composition-based stats.
 Identities = 17/48 (35%), Positives = 28/48 (58%)
 Frame = -1

Query: 300 QIISGLEHLHQRRIVYRDLKPENVLLDNDGNIRISDLGLAVELKEGQN 347
           Q+  G+E+L   + V+RDL   N+LL ++   +ISD G++  L    N
Sbjct: 166 QVSQGMEYLEANKFVHRDLAARNILLCDEHFAKISDFGMSKTLSRENN 23
>20640
          Length = 1492

 Score = 37.7 bits (86), Expect = 0.012,   Method: Compositional matrix adjust.
 Identities = 40/167 (23%), Positives = 74/167 (44%), Gaps = 9/167 (5%)
 Frame = +1

Query: 311 RRIVYRDLKPENVLLDNDGNIRISDLGLA--VELKEGQNKTKGYAGTPGFMAPELLRGEE 368
           R  V+RDL   N L+ +D  ++ISD GLA  V   +    ++  A    +M  E +   +
Sbjct: 1   RGYVHRDLATRNCLVGHDLVVKISDFGLARSVHSVDYYRGSEHDAIPIRWMPLEAILYNK 180

Query: 369 YDFSVDYFALGVTLYEMIA-ARGPFRARGEKVENKELKQ-RIISEPVKYPEKFSQASKDF 426
           +    D ++ GV L+E+ A A  P+     +   + +K+ ++++ P + P    +  K  
Sbjct: 181 FSTQSDVWSFGVVLWEIFAFALQPYYGLTHEEVVRFVKEGKVLACPERTPPPMYELMK-- 354

Query: 427 CEQLLEKDPEKRLGFR--DGTCDALRANVLFKDI---SWRQLEAGML 468
             Q   + P  R  F     T + + +     ++    W  LEA +L
Sbjct: 355 --QCWHRRPATRPSFHTLHKTLENMHSKYEKNEVKLKKWCDLEAAVL 489
>18481
          Length = 437

 Score = 37.7 bits (86), Expect = 0.013,   Method: Composition-based stats.
 Identities = 20/61 (32%), Positives = 35/61 (57%), Gaps = 3/61 (4%)
 Frame = -1

Query: 289 FSEPRAIYYTAQIISGLEHLHQRRIVYRDLKPENVLLD---NDGNIRISDLGLAVELKEG 345
           F+    +  + Q++S LE +HQ+  ++RDLKP+N L+    +   + I D GL+   K+ 
Sbjct: 206 FTLKTILMVSDQLLSRLEFIHQKCFIHRDLKPDNFLMGLGRHCHRLYIIDFGLSKRYKDT 27

Query: 346 Q 346
           Q
Sbjct: 26  Q 24
>27274
          Length = 396

 Score = 37.7 bits (86), Expect = 0.014,   Method: Composition-based stats.
 Identities = 20/70 (28%), Positives = 43/70 (61%), Gaps = 1/70 (1%)
 Frame = -1

Query: 362 ELLRGEEYDFSVDYFALGVTLYEMIAARGPFRA-RGEKVENKELKQRIISEPVKYPEKFS 420
           ELLRG+++  +VD ++LG+ L+E+++   PF   RG    ++++ + +++    Y +   
Sbjct: 375 ELLRGQQHGPTVDMWSLGILLHELLSGHVPFEPERG----SRQMARNMMA---VYAQIIR 217

Query: 421 QASKDFCEQL 430
            +S+D C+ L
Sbjct: 216 GSSRDVCDGL 187
>17516
          Length = 453

 Score = 36.2 bits (82), Expect = 0.032,   Method: Compositional matrix adjust.
 Identities = 16/34 (47%), Positives = 24/34 (70%), Gaps = 1/34 (2%)
 Frame = -3

Query: 353 AGTPGFMAPE-LLRGEEYDFSVDYFALGVTLYEM 385
           AGTP +MAPE LL+  +YD   D ++L + L+E+
Sbjct: 436 AGTPVYMAPEVLLQKGQYDMKADVYSLAIILWEL 335
>18996
          Length = 491

 Score = 36.2 bits (82), Expect = 0.035,   Method: Compositional matrix adjust.
 Identities = 30/103 (29%), Positives = 49/103 (47%), Gaps = 8/103 (7%)
 Frame = +2

Query: 314 VYRDLKPENVLLDNDGNIRISDLGLAVELKEGQNKTKGYAGTP------GFMAPELLRGE 367
           ++RDL   N+L+D    ++ISD GLA    +  N    Y G         + +PE +   
Sbjct: 2   IHRDLAARNILVDRSC-VKISDFGLA----QFANADGYYYGISQRDIPIKWYSPEAIETC 166

Query: 368 EYDFSVDYFALGVTLYEMIAARG--PFRARGEKVENKELKQRI 408
           ++    D ++ GVTL+EM  +RG  P    G  +  +E   R+
Sbjct: 167 KFSSYSDVWSYGVTLFEMF-SRGEIPNLLPGHDLTQEEFLNRL 292
>08294
          Length = 1849

 Score = 36.2 bits (82), Expect = 0.039,   Method: Compositional matrix adjust.
 Identities = 37/183 (20%), Positives = 77/183 (42%), Gaps = 12/183 (6%)
 Frame = +2

Query: 265  LVMTIMNGGDVRYHIYNVDEDN--------PGFSEPRAIYYTAQIISGLEHLHQRRIVYR 316
            L+    + GD++  +     DN        P  +  + +    Q+ +G+E L  + +V+ 
Sbjct: 938  LITEYCDWGDLKQFLLATRNDNGRGRGTRVPALALSQKLGMGQQVAAGMEALSNQGLVHG 1117

Query: 317  DLKPENVLLDNDGNIRISDLGLAVELKEGQNKTKGYAGTP-GFMAPELLRGEEYDFSVDY 375
            DL   NVLL +   ++++   L+ ++   +         P  ++ PE +  +      D 
Sbjct: 1118 DLAARNVLLTSRMQLKVARPALSGDVYASEYYPLHQRLVPLRWLPPEGVLEDSATTCGDV 1297

Query: 376  FALGVTLYEMIA-ARGPFRARG--EKVENKELKQRIISEPVKYPEKFSQASKDFCEQLLE 432
            +A GV L+E++  A  P+R     E + + +  Q  +  P   P   S   +   +Q  +
Sbjct: 1298 WAFGVFLWEVLQLADLPYRLMSDEEVLRSLQHSQAALDSPDAPPALLSLLQRCTAQQPSQ 1477

Query: 433  KDP 435
            + P
Sbjct: 1478 RPP 1486
>11404
          Length = 563

 Score = 35.0 bits (79), Expect = 0.086,   Method: Compositional matrix adjust.
 Identities = 38/155 (24%), Positives = 67/155 (43%), Gaps = 13/155 (8%)
 Frame = +1

Query: 186 GEDWFLDFRV---LGKGGFGEVSACQMKATGKMYACXXXXXXXXXXXXGYQGAIVEKRIL 242
           GE W   + +   +GKG FG+V         +  A                 A +E ++L
Sbjct: 124 GEKWADRYEIDSLIGKGSFGQVVKAYDHTDNEQVAIKIIKNKKPFL----NQAQIEVKLL 291

Query: 243 TKVHSR------FIVSLAYAFETKTDLCLVMTIMNGGDVRYHIYNV--DEDNPGFSEPRA 294
             ++        +IV L   F  ++ LCLV  +++     Y++Y++  + +  G S    
Sbjct: 292 EMMNRHDTDNKYYIVRLKRHFMFRSHLCLVFELLS-----YNLYDLLRNTNFRGVSLNLT 456

Query: 295 IYYTAQIISGLEHLH--QRRIVYRDLKPENVLLDN 327
             +  Q+ + L  L   +  I++ DLKPEN+LL N
Sbjct: 457 RKFAQQLCTALLFLATPEMSIIHCDLKPENILLCN 561
>29360
          Length = 363

 Score = 34.7 bits (78), Expect = 0.12,   Method: Composition-based stats.
 Identities = 21/73 (28%), Positives = 38/73 (52%), Gaps = 4/73 (5%)
 Frame = +3

Query: 257 FETKTDLCLVMTIMNGGDVRYHIYNVDEDNPGFSEPRAIYY----TAQIISGLEHLHQRR 312
           F+ K   CLV  ++       ++Y+  + N    +P  + Y    T Q+++ L  L Q  
Sbjct: 162 FQHKNHTCLVFEML-----EQNLYDFLKQNK--FQPLPLKYIRPITQQVLTALRKLKQLG 320

Query: 313 IVYRDLKPENVLL 325
           +++ DLKPEN++L
Sbjct: 321 LIHADLKPENIML 359
>17253
          Length = 483

 Score = 34.3 bits (77), Expect = 0.13,   Method: Composition-based stats.
 Identities = 13/43 (30%), Positives = 24/43 (55%)
 Frame = -1

Query: 297 YTAQIISGLEHLHQRRIVYRDLKPENVLLDNDGNIRISDLGLA 339
           +   +  G+ H+   +IV+RD+   NVL+      ++SD GL+
Sbjct: 195 FALHVARGMAHVANNKIVHRDVAARNVLISERNVCKVSDFGLS 67
>21800
          Length = 855

 Score = 33.9 bits (76), Expect = 0.17,   Method: Compositional matrix adjust.
 Identities = 24/65 (36%), Positives = 36/65 (55%), Gaps = 2/65 (3%)
 Frame = +2

Query: 300 QIISGLEHLHQR-RIVYRDLKPENVLLDNDGN-IRISDLGLAVELKEGQNKTKGYAGTPG 357
           Q++ GL +LH +  I++ D+KPEN+L+  D N IR     LAV+  E Q       G+  
Sbjct: 656 QVLEGLNYLHAKCNIIHTDIKPENILICVDDNYIR----KLAVDAFEWQRLGLKLPGSAV 823

Query: 358 FMAPE 362
             AP+
Sbjct: 824 STAPK 838
>01106
          Length = 878

 Score = 33.1 bits (74), Expect = 0.28,   Method: Compositional matrix adjust.
 Identities = 13/30 (43%), Positives = 23/30 (76%), Gaps = 1/30 (3%)
 Frame = +3

Query: 300 QIISGLEHLHQR-RIVYRDLKPENVLLDND 328
           Q++ GL ++H + RI++ D+KPEN+L+  D
Sbjct: 669 QVLEGLSYMHAKCRIIHTDIKPENILICVD 758
>33586
          Length = 551

 Score = 30.8 bits (68), Expect = 1.4,   Method: Composition-based stats.
 Identities = 13/27 (48%), Positives = 19/27 (70%)
 Frame = +2

Query: 249 FIVSLAYAFETKTDLCLVMTIMNGGDV 275
           FIV L YAF+T+  L L++  + GGD+
Sbjct: 404 FIVHLHYAFQTEGKLYLILEFLRGGDL 484
>21418
          Length = 831

 Score = 29.6 bits (65), Expect = 3.2,   Method: Compositional matrix adjust.
 Identities = 17/44 (38%), Positives = 24/44 (54%), Gaps = 4/44 (9%)
 Frame = +2

Query: 404 LKQRIISEPVKYPE----KFSQASKDFCEQLLEKDPEKRLGFRD 443
           +K+RI S    +P+      SQA+KD  + +L  DP KRL   D
Sbjct: 2   MKKRIRSGQYDFPDPEWTNVSQAAKDLIKGMLNVDPSKRLCIED 133
>36481
          Length = 806

 Score = 29.6 bits (65), Expect = 3.3,   Method: Compositional matrix adjust.
 Identities = 32/138 (23%), Positives = 60/138 (43%), Gaps = 10/138 (7%)
 Frame = +2

Query: 197 GKGGFGEVSACQMKATGKMYACXXXXXXXXXXXXGYQGAIVEKRILTKV-----HSRFI- 250
           G+G FG+V  C+    G   A               + A +E  +L K+     H++ + 
Sbjct: 389 GEGTFGKVVQCKDLLKGDDIALKIIKNVDKYR----EAAKLEINVLEKLREKDPHAKHMC 556

Query: 251 VSLAYAFETKTDLCLVMTIMNGGDVRYHIYNVDEDNPGFSEP----RAIYYTAQIISGLE 306
           V +   F+    +C+   ++        +++  +DN   + P    R I Y  Q+   + 
Sbjct: 557 VQMLDWFDYHGHVCISFHMLGLS-----VFDFLKDNSYGAYPIEQVRHISY--QLCYAVN 715

Query: 307 HLHQRRIVYRDLKPENVL 324
            LH+ ++ + DLKPEN+L
Sbjct: 716 FLHENQLTHTDLKPENIL 769
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|7710012|ref|NP_057878.1| crystallin, mu [Mus
musculus]
         (313 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

19490                                                                 147   7e-36
00556                                                                  29   2.7  
>19490
          Length = 411

 Score =  147 bits (370), Expect = 7e-36,   Method: Compositional matrix adjust.
 Identities = 71/109 (65%), Positives = 88/109 (80%)
 Frame = +3

Query: 197 ADVIITVTMATEPILFGEWVKPGAHINAVGASRPDWRELDDELMRQAVLYVDSREAALKE 256
           ADVI+TVT ++ PIL  +WVKPGAHINAVG+ RPDW ELD +LM+QA +YVDSRE+A+KE
Sbjct: 6   ADVIVTVTNSSTPILMADWVKPGAHINAVGSCRPDWNELDPKLMQQAAVYVDSRESAVKE 185

Query: 257 SGDVLLSGADIFAELGEVISGAKPAHCEKTTVFKSLGMAVEDLVAAKLV 305
           SGDV+ SGA I  E+GE+I G   A   +TTVFKSLG+A+ED +AA LV
Sbjct: 186 SGDVIKSGATIAGEIGELILGKVQARKSETTVFKSLGLAIEDAMAADLV 332
>00556
          Length = 2189

 Score = 28.9 bits (63), Expect = 2.7,   Method: Compositional matrix adjust.
 Identities = 17/49 (34%), Positives = 27/49 (55%)
 Frame = +3

Query: 31  LANFSKGPDGGVMQPVRTVVPVAKHRGFLGVMPAYSAAEDALTTKLVTF 79
           L   S+ P   V   V TVV  + H+ F+G +P+Y  +ED +   L++F
Sbjct: 687 LPGLSENPTQAVPGVVSTVVQDSDHKIFMGGLPSY-LSEDQMKELLLSF 830
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|58037259|ref|NP_082165.1| vacuolar protein sorting 11
[Mus musculus]
         (941 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

28086                                                                 148   9e-36
10203                                                                  43   6e-04
20496                                                                  37   0.032
07370                                                                  33   0.52 
14716                                                                  32   0.80 
33313                                                                  29   8.0  
>28086
          Length = 421

 Score =  148 bits (374), Expect = 9e-36,   Method: Compositional matrix adjust.
 Identities = 68/101 (67%), Positives = 82/101 (81%), Gaps = 1/101 (0%)
 Frame = +2

Query: 809 ELKASPKIFQKTKCSICNSALELPSVHFLC-GHSFHQHCFESYSESDADCPTCLPENRKV 867
           EL+ S KIFQ +KC+ICN + ELPSVHFLC  HS+HQHCFESYSESD +CP C PENRK 
Sbjct: 2   ELQTSAKIFQASKCNICNHSPELPSVHFLCEPHSYHQHCFESYSESDMECPACAPENRKF 181

Query: 868 MDMIRAQEQKRDLHDQFQHQLKCSNDSFSVIADYFGRGVFN 908
           MD+IRAQE  RD H+ F +QL+ + D F+V+ADYFGRG+FN
Sbjct: 182 MDIIRAQEMTRDSHESFHNQLERAPDGFAVVADYFGRGLFN 304
>10203
          Length = 2103

 Score = 42.7 bits (99), Expect = 6e-04,   Method: Compositional matrix adjust.
 Identities = 24/68 (35%), Positives = 30/68 (44%)
 Frame = -2

Query: 793  VRRYREETTRIRQEIQELKASPKIFQKTKCSICNSALELPSVHFLCGHSFHQHCFESYSE 852
            VR  +       QE  EL A        +C+IC   +E  +    CGH FH  C  S+ E
Sbjct: 1175 VRNMQARFPMATQEDLELNAD-------ECAICWEGME-AARKLPCGHLFHNSCLRSWLE 1020

Query: 853  SDADCPTC 860
             D  CPTC
Sbjct: 1019 QDTSCPTC 996
>20496
          Length = 573

 Score = 37.4 bits (85), Expect = 0.032,   Method: Compositional matrix adjust.
 Identities = 22/75 (29%), Positives = 35/75 (46%), Gaps = 3/75 (4%)
 Frame = -2

Query: 847 FESYSESDADCPTCLPENRKVMDMIRAQ---EQKRDLHDQFQHQLKCSNDSFSVIADYFG 903
           F +Y  +   C   L     V+D+I+ +   E  RD+      Q+    + +SVI D  G
Sbjct: 344 FNTYGGNPVSCAISL----AVLDVIKEEQLMEHARDVGGYLTQQILTLKEKYSVIGDVRG 177

Query: 904 RGVFNKLTLLTDPPT 918
           RG+F  + L+ D  T
Sbjct: 176 RGLFVGIDLVKDRDT 132
>07370
          Length = 3144

 Score = 33.1 bits (74), Expect = 0.52,   Method: Compositional matrix adjust.
 Identities = 17/52 (32%), Positives = 25/52 (48%), Gaps = 1/52 (1%)
 Frame = -3

Query: 545  MKRYG-KTLMHHIPEQTTQLLKGLCTDYRPSLEGRGDREALSCRASSEEFIP 595
            + RY  KT+ H+  +    ++   CT Y PS  G  D E L C  ++   IP
Sbjct: 1603 LNRYALKTIQHNTKQNNGNVINKNCTSYNPS-NGHFDWEHLPCVFTNHSHIP 1451
>14716
          Length = 481

 Score = 32.3 bits (72), Expect = 0.80,   Method: Composition-based stats.
 Identities = 16/50 (32%), Positives = 24/50 (48%), Gaps = 3/50 (6%)
 Frame = +2

Query: 821 KCSICNSALELPSVHFLCGHSFHQHCFESYSESDADCPTC---LPENRKV 867
           KCS+C       ++  +CGH F   C   + +  A+CP C    P +R V
Sbjct: 149 KCSLCLGPRRRTTLT-VCGHLFCWDCIHQWCQEKAECPLCREQFPPHRLV 295
>33313
          Length = 566

 Score = 29.3 bits (64), Expect = 8.0,   Method: Compositional matrix adjust.
 Identities = 17/48 (35%), Positives = 24/48 (50%), Gaps = 3/48 (6%)
 Frame = -3

Query: 803 IRQEIQELKASPKIFQ-KTKCSICNSAL--ELPSVHFLCGHSFHQHCF 847
           IR+EIQ  +    + + + KCS+C+  L    P   F C H FH  C 
Sbjct: 264 IRREIQSFRNKYTLVKAEDKCSVCSYPLMTRPPFYLFPCTHKFHMDCL 121
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|117606375|ref|NP_036019.2| septin 3 [Mus musculus]
         (337 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

14132                                                                 146   1e-35
14677                                                                  81   5e-19
34156                                                                  75   3e-14
29788                                                                  74   9e-14
22078                                                                  72   3e-13
38061                                                                  30   1.1  
34960                                                                  29   2.1  
32931                                                                  28   6.1  
32225                                                                  28   6.3  
>14132
          Length = 422

 Score =  146 bits (369), Expect = 1e-35,   Method: Compositional matrix adjust.
 Identities = 69/140 (49%), Positives = 98/140 (70%)
 Frame = -2

Query: 116 FGDQINNENCWEPIEKYINEQYEKFLKEEVNIARKKRIPDTRVHCCLYFISPTGHSLRPL 175
           FGD ++N NCW+PI  YI+ +YE++L  E  + R   +PDTRVHCCLYFI+PTGH L+PL
Sbjct: 421 FGDAVDNSNCWQPITDYIDSKYEEYLNAESRVNRTV-MPDTRVHCCLYFIAPTGHGLKPL 245

Query: 176 DLEFMKHLSKVVNIIPVIAKADTMTLEEKSEFKQRVRKELEVNGIEFYPQKEFDEDLEDK 235
           D+EFMK L   VNIIP++AKADT+T +E  EFK+ +  E+  + I+ Y   + D++ E K
Sbjct: 244 DVEFMKRLHDKVNIIPLVAKADTLTPDECREFKKTILNEIAQHKIKIYEFPDCDDEEEMK 65

Query: 236 TENDKIRQESMPFAVVGSDK 255
            +      + +PFAVVGS++
Sbjct: 64  IQKRLRVSDRVPFAVVGSNR 5
>14677
          Length = 378

 Score = 81.3 bits (199), Expect(2) = 5e-19,   Method: Compositional matrix adjust.
 Identities = 36/76 (47%), Positives = 52/76 (68%), Gaps = 1/76 (1%)
 Frame = -1

Query: 90  VEIKAIGHVIEEGGVKMKLTVIDTPGFGDQINNENCWEPIEKYINEQYEKFLKEEVNIAR 149
           V++KA  + + E  V++KLT +DT GFGDQIN  + W+PI  YI+ Q++ +L+EE+ I R
Sbjct: 228 VKLKAHTYDLTEKNVRLKLTTVDTTGFGDQINKADSWKPIVDYIDAQFDAYLQEELKIKR 49

Query: 150 K-KRIPDTRVHCCLYF 164
                 D+RVH CLYF
Sbjct: 48  MLHSYHDSRVHACLYF 1

 Score = 30.8 bits (68), Expect(2) = 5e-19,   Method: Compositional matrix adjust.
 Identities = 16/48 (33%), Positives = 27/48 (56%)
 Frame = -3

Query: 32  DTIIEQMRKKTMKTGFDFNIMVVGQSGLGKSTLVNTLFKSQVSRKASS 79
           D ++  +  K   + F     V+G++G+GKSTL++TLF +      SS
Sbjct: 376 DQLVTSLSLKASASTF----FVLGETGIGKSTLMDTLFNTNFDSTPSS 245
>34156
          Length = 348

 Score = 75.5 bits (184), Expect = 3e-14,   Method: Compositional matrix adjust.
 Identities = 40/77 (51%), Positives = 57/77 (74%)
 Frame = -1

Query: 37  QMRKKTMKTGFDFNIMVVGQSGLGKSTLVNTLFKSQVSRKASSWNREEKIPKTVEIKAIG 96
           Q+ +K++K GF+F +MVVG+SGLGKSTLVN+LF + +  +    +  EKI +TV+I A  
Sbjct: 231 QVHRKSVKKGFEFTLMVVGESGLGKSTLVNSLFLTDLYPERHIPSASEKIQQTVKIDAST 52

Query: 97  HVIEEGGVKMKLTVIDT 113
             IEE GVK++LTV+DT
Sbjct: 51  VEIEERGVKLRLTVVDT 1
>29788
          Length = 687

 Score = 73.9 bits (180), Expect = 9e-14,   Method: Compositional matrix adjust.
 Identities = 29/47 (61%), Positives = 39/47 (82%)
 Frame = +3

Query: 270 PWGIIEVENLNHCEFALLRDFVIRTHLQDLKEVTHNIHYETYRAKRL 316
           PWGI+EVENL H +F  LR+ +IRTH+QDLK+VT+N+HYE +R  +L
Sbjct: 3   PWGIVEVENLEHNDFIALRNMLIRTHMQDLKDVTNNVHYENFRYNKL 143
>22078
          Length = 417

 Score = 72.0 bits (175), Expect = 3e-13,   Method: Compositional matrix adjust.
 Identities = 27/48 (56%), Positives = 38/48 (79%)
 Frame = +3

Query: 266 GRKTPWGIIEVENLNHCEFALLRDFVIRTHLQDLKEVTHNIHYETYRA 313
           GR  PWGI+EV+N +HC+F  LR  +I TH+QDLK+VT ++HYE +R+
Sbjct: 6   GRAYPWGIVEVDNXSHCDFIRLRQMLISTHMQDLKDVTSDVHYENFRS 149
>38061
          Length = 206

 Score = 30.4 bits (67), Expect = 1.1,   Method: Composition-based stats.
 Identities = 12/26 (46%), Positives = 17/26 (65%)
 Frame = +3

Query: 246 MPFAVVGSDKEYQVNGKRVLGRKTPW 271
           +PFAVVGS+ E ++  K V  R+  W
Sbjct: 129 LPFAVVGSNDEVKIGNKMVKARQGSW 206
>34960
          Length = 668

 Score = 29.3 bits (64), Expect = 2.1,   Method: Compositional matrix adjust.
 Identities = 15/52 (28%), Positives = 27/52 (51%)
 Frame = +1

Query: 286 LLRDFVIRTHLQDLKEVTHNIHYETYRAKRLNDNGGLPPVSVDTEESHDSNP 337
           L+R F  R H   +  +  ++H E     R++    +PPV+  ++ S +SNP
Sbjct: 13  LVRPFPDRRHRHSIGSLAPSVHGE--GEGRMDGGSAVPPVTASSQGSLNSNP 162
>32931
          Length = 651

 Score = 27.7 bits (60), Expect = 6.1,   Method: Compositional matrix adjust.
 Identities = 28/98 (28%), Positives = 44/98 (44%)
 Frame = +3

Query: 57  SGLGKSTLVNTLFKSQVSRKASSWNREEKIPKTVEIKAIGHVIEEGGVKMKLTVIDTPGF 116
           + LGK T+     K  + +K S     +K+   + I  IG   +   ++  L  ID    
Sbjct: 135 THLGKVTMTYLCSKYTLQKKIS-----KKLKYIILI*KIG---DYAKIRNHLNEIDWAEQ 290

Query: 117 GDQINNENCWEPIEKYINEQYEKFLKEEVNIARKKRIP 154
               N E CW  I+  I E  EK++  +VN ++KK  P
Sbjct: 291 MKSSNLEECWLCIKWIIQETMEKYI-PKVNFSQKKNKP 401
>32225
          Length = 276

 Score = 27.7 bits (60), Expect = 6.3,   Method: Compositional matrix adjust.
 Identities = 18/49 (36%), Positives = 26/49 (53%)
 Frame = -2

Query: 108 LTVIDTPGFGDQINNENCWEPIEKYINEQYEKFLKEEVNIARKKRIPDT 156
           L  ID        N E CW  I++ I E  EK++  +VN ++KK+I  T
Sbjct: 272 LNEIDWAEQMKSSNVEECWLCIKRIIQEAMEKYI-PKVNFSQKKKIKPT 129
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|19549323|ref|NP_598767.1| retinol dehydrogenase 5
[Mus musculus]
         (318 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

07400                                                                 146   1e-35
30930                                                                 100   4e-35
05690                                                                 141   4e-34
35613                                                                 137   4e-33
03983                                                                  70   2e-12
31065                                                                  55   3e-08
12758                                                                  52   2e-07
30783                                                                  42   6e-07
18041                                                                  48   5e-06
28229                                                                  48   6e-06
23588                                                                  46   2e-05
05194                                                                  45   3e-05
05235                                                                  37   0.013
26417                                                                  32   0.31 
01050                                                                  31   0.65 
07690                                                                  27   8.6  
>07400
          Length = 1577

 Score =  146 bits (369), Expect = 1e-35,   Method: Compositional matrix adjust.
 Identities = 89/269 (33%), Positives = 141/269 (52%), Gaps = 9/269 (3%)
 Frame = -3

Query: 22   QSLPASDAFIFITGCDSGFGRLLALQLDQKGFQVLAGCL--TPSGAEDLQQMASSRLHTT 79
            + +PA D  + ITGCD+G G   AL+ +++G  V+AGCL  T SGA+ L +     +H  
Sbjct: 1458 RDVPAKDKVVLITGCDTGIGHEAALEANKRGLTVVAGCLDVTSSGAQRLAE--KKGVHVI 1285

Query: 80   LLDITDPQNVQQVAKWVKTRVGETGLFGLVNNAGVAGIIGPTPWLTQDDFQRVLSVNTLG 139
             LD++  ++V    K V       GL+ ++NNAG    + P    +   F  V  V   G
Sbjct: 1284 RLDVSSDESVANAMKSVSKLCEAKGLWAVINNAGF-NRMSPVELTSMTTFHHVADVMLFG 1108

Query: 140  PIGVTLALLPLLQQARGRVVNITSVLGRIA-ANGGGYCVSKFGLEAFSDSLRRDMAPFGV 198
             + VT A+LPL+++A+GRVV ++S  G    A    YC++KFG+EAFSD  R +M  + V
Sbjct: 1107 TVRVTKAVLPLVRRAKGRVVTVSSDRGMTTPAYSSAYCIAKFGVEAFSDVXRMEMKKYDV 928

Query: 199  QVSIVEPGFF--RTPVTNLESLESTLKACWARLPPAIQ----AHYGEAFLDTYLRVQRRI 252
             VSI++PG F   T + + + +E+  K     L    +    A+ G+  +   +   R  
Sbjct: 927  SVSIIQPGHFGGATSILDTQQMEAMQKVMDKDLQACSEDVRTAYGGQRAVTEIIEGCREC 748

Query: 253  MNLICDPELTKVTSCLEHALTARHPRTRY 281
             N     ++T V   + H++ + HP TRY
Sbjct: 747  KNY-SASDVTPVVEAMMHSVLSTHPYTRY 664
>30930
          Length = 1452

 Score = 99.8 bits (247), Expect(2) = 4e-35,   Method: Compositional matrix adjust.
 Identities = 58/168 (34%), Positives = 94/168 (55%), Gaps = 3/168 (1%)
 Frame = -3

Query: 21   RQSLPASDAFIFITGCDSGFGRLLALQLDQKGFQVLAGCLTPSGAEDLQ-QMASSRLHTT 79
            R+SL ++   + ITGCD GFG L A +L   G++V AGC   +G    Q ++ S  +   
Sbjct: 1378 RRSLSSTGKAVLITGCDRGFGFLSAQRLSSLGYRVFAGCFDATGEGAAQLRLTSPNIDVI 1199

Query: 80   LLDITDPQNVQQVAKWVKTRVGETGLFGLVNNAGVAGIIG-PTPWLTQDDFQRVLSVNTL 138
             LD+T+   V++  ++   ++   GL+ +VNNAG   + G    W +    QR++ VN L
Sbjct: 1198 QLDVTNDGQVEEARRFXDEQLQGYGLWAIVNNAGT--LFGAEVEWCSLSRXQRMMDVNWL 1025

Query: 139  GPIGVTLALLPLLQQARGRVVNITSVLGRIAANGGG-YCVSKFGLEAF 185
            G + +T A LP ++  +GRV+N+ S+ GR+A  G   Y  +KF +  F
Sbjct: 1024 GTVRITQAFLPYVRSVKGRVINVASLSGRVALPGYALYSSTKFAVVGF 881

 Score = 65.9 bits (159), Expect(2) = 4e-35,   Method: Compositional matrix adjust.
 Identities = 35/99 (35%), Positives = 56/99 (56%), Gaps = 2/99 (2%)
 Frame = -2

Query: 185 FSDSLRRDMAPFGVQVSIVEPGFFRTPVTNLESLESTLKACWARLPPAIQAHYGEAFLDT 244
           FSDSLRR+M  F V+V  +EP  +RT + + +SL+   K  W   P  ++  +GE +   
Sbjct: 884 FSDSLRREMFKFDVKVITIEPSGYRTVLMDPDSLKRQSKQVWDEAPAEVRRDFGEKY--- 714

Query: 245 YLRVQRRIMNLI--CDPELTKVTSCLEHALTARHPRTRY 281
           +L  Q +I  L+    P++ +V   + HA+T+ HP  RY
Sbjct: 713 FLGFQDKIAQLLRFSSPKIYQVVDDVTHAVTSAHPYKRY 597
>05690
          Length = 1192

 Score =  141 bits (355), Expect = 4e-34,   Method: Compositional matrix adjust.
 Identities = 95/278 (34%), Positives = 144/278 (51%), Gaps = 4/278 (1%)
 Frame = +2

Query: 24  LPASDAFIFITGCDSGFGRLLALQLDQKGFQVLAGCLTP--SGAEDLQQMASSRLHTTLL 81
           LPA    +FITGCD+G G LLA+ LD+ G +V AGCL P   G + L+   S RL T  L
Sbjct: 161 LPAEGKAVFITGCDAGLGHLLAIHLDKLGVKVFAGCLFPGGEGEQTLKAKCSQRLCTVPL 340

Query: 82  DITDPQNVQQVAKWVKTRVGETGLFGLVNNAGVAGIIGPTPWLTQDDFQRVLSVNTLGPI 141
           D+   + V   A  VK  +    L+G+VNNAG+   IG    + Q D  ++L VN  G +
Sbjct: 341 DVCSLEIVTTAADTVKRELDGQELWGVVNNAGIMH-IGCLEVMGQADVDKILDVNYRGQV 517

Query: 142 GVTLALLPLLQQARGRVVNITSVLGRI-AANGGGYCVSKFGLEAFSDSLRRDMAPFGVQV 200
            V  A LP L+++RGR+VN+ S  G         YC SK  + A ++SLR ++ PFGV+V
Sbjct: 518 NVIRAFLPFLRRSRGRLVNVASNTGIAPVPYHAVYCASKAAVAALTESLRLELQPFGVRV 697

Query: 201 SIVEPGFFRTPVTNLESLESTLKACWARLPPAIQAHYGEAFLDTYL-RVQRRIMNLICDP 259
           S + P  +RT +    + ++T    WA+    ++  YG    D++  + + +      + 
Sbjct: 698 STIIPSGYRTGIQQ-HNTQTTGDKWWAQAKQEVRDSYGH---DSFTPQNKTKDYKSYLNA 865

Query: 260 ELTKVTSCLEHALTARHPRTRYSPGWDAKLLWLPASYL 297
           + + +   +  AL    P+  Y  G+ A    LP  YL
Sbjct: 866 DFSGIIHKMSDALLEMCPQDYYYKGFLAT--SLPFLYL 973
>35613
          Length = 977

 Score =  137 bits (346), Expect = 4e-33,   Method: Compositional matrix adjust.
 Identities = 86/267 (32%), Positives = 135/267 (50%), Gaps = 8/267 (2%)
 Frame = +1

Query: 23  SLPASDAFIFITGCDSGFGRLLALQLDQKGFQVLAGCLTPSG--AEDLQQMASSRLHTTL 80
           S+   D  + ITGCD+GFG  LA  L + G  V+A    P G  A+ L+ +++ R+    
Sbjct: 70  SVCLRDKTVLITGCDTGFGHALAKSLHEDGCHVIATVYQPDGDGAKRLRDVSTDRMTVIP 249

Query: 81  LDITDPQNVQQVAKWVKTRVGETGLFGLVNNAGVAGIIGPTPWLTQDDFQRVLSVNTLGP 140
           LD++   +V++  + VK     +GL+GLVNNAG    +G     T   +  V ++N  G 
Sbjct: 250 LDVSSDDSVEKCLRHVKQLCEHSGLWGLVNNAG-HNFVGEVELTTMRQYLMVANINIFGM 426

Query: 141 IGVTLALLPLLQQARGRVVNITSVLGRIAA-NGGGYCVSKFGLEAFSDSLRRDMAPFGVQ 199
           +  T A LPLL+ A GR+VN+TS+ G+++      Y ++K+  E FS+  + +M  FGV+
Sbjct: 427 VRTTRAFLPLLRHATGRIVNVTSIKGQLSTPMNAAYNITKYAGETFSEITQMEMKQFGVK 606

Query: 200 VSIVEPGFFRTPVTNLES-----LESTLKACWARLPPAIQAHYGEAFLDTYLRVQRRIMN 254
           VSIVEPG F      +       +       W      ++  + +  LD ++R +     
Sbjct: 607 VSIVEPGNFGGATGCINEPGRNRIRREFDEMWTEASDEVKRVFSKHQLDDFIR-ELEDGA 783

Query: 255 LICDPELTKVTSCLEHALTARHPRTRY 281
           L   P LT V   +  ALT+  P  RY
Sbjct: 784 LTTYPTLTPVIRAITDALTSGDPNFRY 864
>03983
          Length = 1099

 Score = 69.7 bits (169), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 58/191 (30%), Positives = 90/191 (47%), Gaps = 11/191 (5%)
 Frame = +2

Query: 31  IFITGCDSGFGRLLALQLDQKGFQVLAGCLTPSGAE----DLQQMASSRLHTTLLDITDP 86
           + ITG  SG G+L+A +    G  ++   +     E    D+ Q  S + +T  +D++  
Sbjct: 185 VLITGAGSGLGKLMAYRFMGLGCDLVLWDINTEAIEAMERDMGQQVSCKAYT--VDLSSR 358

Query: 87  QNVQQVAKWVKTRVGETGLFGLVNNAGVAGIIGPTPWLTQDD--FQRVLSVNTLGPIGVT 144
           + + + A  VK  VG  G+  LVNNAG   I+    +L   D   ++ + VN+       
Sbjct: 359 EQIYKAADQVKREVG--GVDILVNNAG---IVTGRKFLDCPDSLIEKTMEVNSNAHFWTV 523

Query: 145 LALLP-LLQQARGRVVNITSVLGRIAANG-GGYCVSKFGLEAFSDSLRRD---MAPFGVQ 199
            A LP +L Q +G +++I S  G     G   YC SKF    F +SLR +   M   GV 
Sbjct: 524 KAFLPNMLAQNKGHIISIASSAGLFGVTGLADYCASKFAAVGFDESLRFELEAMGKTGVH 703

Query: 200 VSIVEPGFFRT 210
            ++V P F  T
Sbjct: 704 TTVVCPYFINT 736
>31065
          Length = 357

 Score = 55.5 bits (132), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 33/118 (27%), Positives = 57/118 (48%)
 Frame = +2

Query: 198 VQVSIVEPGFFRTPVTNLESLESTLKACWARLPPAIQAHYGEAFLDTYLRVQRRIMNLIC 257
           ++V ++EPG+F+T + +  +L S  K  +   P  I+ HY    ++ + R+ ++      
Sbjct: 20  IKVCMIEPGYFKTDIIHFSNLTSAYKKGFDSTPDDIKKHYPHLSVERFARIIQKTREGAS 199

Query: 258 DPELTKVTSCLEHALTARHPRTRYSPGWDAKLLWLPASYLPARVVDAVLTWILPRPAQ 315
           D ++ +V   LE ALT+R P TR   G DA+ +             A + W LP P  
Sbjct: 200 D-DIGQVIDALELALTSRFPPTRQLVGKDARFI-------------APVLWNLPAPCH 331
>12758
          Length = 804

 Score = 52.4 bits (124), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 35/126 (27%), Positives = 65/126 (51%), Gaps = 1/126 (0%)
 Frame = -1

Query: 82  DITDPQNVQQVAKWVKTRVGETGLFGLVNNAGVAGIIGPTPWLTQDDFQRVLSVNTLGPI 141
           D+T   + ++V +    + G   +  LVN AG+  + G     + D + R+ + N     
Sbjct: 717 DLTKEDDTKRVVEETVKQFGRLNI--LVNCAGIIEL-GNIENTSLDQYDRMFNTNVRSVY 547

Query: 142 GVTLALLPLLQQARGRVVNITSVLG-RIAANGGGYCVSKFGLEAFSDSLRRDMAPFGVQV 200
            +T+  +P L   +G +VN++SV G R   N   YC++K  ++ F+  +  ++AP  V+V
Sbjct: 546 HLTMLAVPHLVNTQGNIVNVSSVNGMRSFPNVLAYCMAKSAIDQFTRCVALELAPKKVRV 367

Query: 201 SIVEPG 206
           + V PG
Sbjct: 366 NGVNPG 349
>30783
          Length = 765

 Score = 41.6 bits (96), Expect(2) = 6e-07,   Method: Compositional matrix adjust.
 Identities = 21/53 (39%), Positives = 34/53 (64%), Gaps = 1/53 (1%)
 Frame = +1

Query: 155 RGRVVNITSVLG-RIAANGGGYCVSKFGLEAFSDSLRRDMAPFGVQVSIVEPG 206
           +G +VN++S+   R  A  G YC+SK  ++ F+  L  ++AP GV+V+ V PG
Sbjct: 178 KGCIVNVSSICASRPMAEVGVYCMSKAAMDMFTQCLALELAPHGVRVNSVNPG 336

 Score = 28.9 bits (63), Expect(2) = 6e-07,   Method: Compositional matrix adjust.
 Identities = 15/49 (30%), Positives = 26/49 (53%)
 Frame = +2

Query: 108 LVNNAGVAGIIGPTPWLTQDDFQRVLSVNTLGPIGVTLALLPLLQQARG 156
           LVNNAGVA  + P    T++ +  ++ +N      ++  L P L + +G
Sbjct: 41  LVNNAGVARFVKPCDT-TEEQYDEIMDINMKSVFFLSKLLAPELIKRKG 184
>18041
          Length = 547

 Score = 48.1 bits (113), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 44/182 (24%), Positives = 80/182 (43%), Gaps = 6/182 (3%)
 Frame = -2

Query: 35  GCDSGFGRLLALQLDQKGFQVLAGCLTPSGAEDLQQMASSRLHTTLLDITDPQNVQQVAK 94
           G   G G+  ALQL +KG  ++     P     + +    +   ++  IT       +  
Sbjct: 546 GSTDGIGKCFALQLAEKGLDIVLISRNPEKLSAVAKEIVDQHKVSVKVITADFKNADIYD 367

Query: 95  WVKTRVGETGLFGLVNNAGVAGIIGPTPWLTQDDF----QRVLSVNTLGPIGVTLALLP- 149
            +K ++    +  LVNN G+     P  +   DDF    Q +++VN L  + +T  +LP 
Sbjct: 366 NIKRQLTGLDIGILVNNVGMLNRRNPGYFCEADDFEQFHQDIINVNILACVQMTGIVLPE 187

Query: 150 LLQQARGRVVNITSVLG-RIAANGGGYCVSKFGLEAFSDSLRRDMAPFGVQVSIVEPGFF 208
           +L++ RG ++NI S    R       Y  +K  +  F+ +L  + +  GV + ++ P   
Sbjct: 186 MLERKRGLIINIASGAAIRPLPFFSVYSGTKAFISHFTQALNMEYSSQGVTIQLLIPNLV 7

Query: 209 RT 210
            T
Sbjct: 6   AT 1
>28229
          Length = 633

 Score = 47.8 bits (112), Expect = 6e-06,   Method: Compositional matrix adjust.
 Identities = 34/95 (35%), Positives = 50/95 (52%), Gaps = 2/95 (2%)
 Frame = -1

Query: 144 TLALLPLLQQARGRVVNITSVLGRIAANGG-GYCVSKFGLEAFSDSLRRDMAPFGVQVSI 202
           T A LP L + +G VVN++S  G     G   Y +SK  L+ F+  +  ++AP GV+V+ 
Sbjct: 309 TKAALPHLLKTKGAVVNVSSCAGICHFPGALSYGISKAALDQFTKIVSLELAPQGVRVNS 130

Query: 203 VEPGFFRTPVTNLESLESTLKACWARLPP-AIQAH 236
           V PGF    VTN+ S    +   +  L   AI +H
Sbjct: 129 VNPGFV---VTNIHSRIGIVDEAYKSLHERAINSH 34
>23588
          Length = 611

 Score = 46.2 bits (108), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 37/117 (31%), Positives = 61/117 (52%), Gaps = 3/117 (2%)
 Frame = +3

Query: 82  DITDPQNVQQVAKWVKTRVGETGLFGLVNNAGVA--GIIGPTPWLTQDDFQRVLSVNTLG 139
           D+TD    QQ+      + G+  +  LVNNAG A  G++   P +  ++   V S+N   
Sbjct: 147 DLTDETFRQQLVASTVDKFGQIDV--LVNNAGFANPGLLS-BPGM--ENLLNVFSLNLNA 311

Query: 140 PIGVTLALLPLLQQARGRVVNITSVLG-RIAANGGGYCVSKFGLEAFSDSLRRDMAP 195
            + ++   +P L Q++G +VNI+S L  R +   G YC+SK     F+  L  ++AP
Sbjct: 312 HVAMSKLCVPHLLQSKGNIVNISSNLSMRPSPALGAYCMSKRHWTCFTRVLAYELAP 482
>05194
          Length = 1075

 Score = 45.4 bits (106), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 25/75 (33%), Positives = 46/75 (61%), Gaps = 5/75 (6%)
 Frame = +1

Query: 150 LLQQARGRVVNITSVLGRIAANG-GGYCVSKFGLEAFSDSLRRDMAPFGVQVSIVEPGFF 208
           ++++  G ++NI+S  GR    G   Y  SKF +E  S ++R ++A  GV+V+ ++PG  
Sbjct: 22  MVKRESGHIINISSDAGRKGFPGLAVYSGSKFFVEGLSQAMRSEVADSGVKVTCIQPGDV 201

Query: 209 RTPV----TNLESLE 219
           +TP+    T+ E++E
Sbjct: 202 KTPLFGLSTDREAIE 246
>05235
          Length = 944

 Score = 36.6 bits (83), Expect = 0.013,   Method: Compositional matrix adjust.
 Identities = 31/112 (27%), Positives = 48/112 (42%), Gaps = 5/112 (4%)
 Frame = -2

Query: 108 LVNNAGVAGIIGPTPWLTQDDFQRVLSVNTLGPIGVTLALLPLLQQARG----RVVNITS 163
           L+N AG+         L     +R ++VN  G +  T A++    + +G     + NI S
Sbjct: 622 LINGAGI---------LDDHQIERTIAVNFTGTVNTTTAIMEFWDKRKGGPGGVIANICS 470

Query: 164 VLG-RIAANGGGYCVSKFGLEAFSDSLRRDMAPFGVQVSIVEPGFFRTPVTN 214
           V G         Y  SK    +F++SL +     GV V  + PG   TP+ N
Sbjct: 469 VTGFNSIYQVPVYSASKAXALSFTNSLAKLAHITGVTVYSINPGITHTPLVN 314
>26417
          Length = 929

 Score = 32.0 bits (71), Expect = 0.31,   Method: Compositional matrix adjust.
 Identities = 38/124 (30%), Positives = 56/124 (45%), Gaps = 17/124 (13%)
 Frame = +1

Query: 108 LVNNAGVAGIIGPTPWLTQDDFQRVLSVNTLGPIGVTLALLPLLQ-QARGRVVNITSVL- 165
           L+NNAGV   IG    LT+D  +   + N  GP  +T  LL  L+  A  R++N++SV+ 
Sbjct: 19  LINNAGV---IGLPYALTEDGLETNFATNHFGPFLLTNLLLDKLKSSAPSRIINVSSVVQ 189

Query: 166 --GRIAANG----------GGYCVSKFGLEAFSDSLRRDMAPFG---VQVSIVEPGFFRT 210
             G+I  +             Y  SK     F+  L R +   G   V V  + PG  +T
Sbjct: 190 KAGKIDLDNLKAEKYFKEHKIYFNSKLANVLFTRELARRLVATGVTDVTVHCLHPGSXKT 369

Query: 211 PVTN 214
            + N
Sbjct: 370 DLLN 381
>01050
          Length = 877

 Score = 31.2 bits (69), Expect = 0.65,   Method: Compositional matrix adjust.
 Identities = 14/60 (23%), Positives = 23/60 (38%)
 Frame = +3

Query: 238 GEAFLDTYLRVQRRIMNLICDPELTKVTSCLEHALTARHPRTRYSPGWDAKLLWLPASYL 297
            + F  T+L  Q  +  L   P + +   C             Y+ GW+ +LLW+   Y 
Sbjct: 687 SQNFASTFLICQTVLCFLFSFPRICQSIGCFVVIYVLPSVSVNYNEGWNLQLLWVFVKYF 866
>07690
          Length = 992

 Score = 27.3 bits (59), Expect = 8.6,   Method: Compositional matrix adjust.
 Identities = 12/28 (42%), Positives = 17/28 (60%)
 Frame = +1

Query: 112 AGVAGIIGPTPWLTQDDFQRVLSVNTLG 139
           AG AG+ GP  WL +   + VLS+ + G
Sbjct: 676 AG*AGVSGPVSWLAKSSARPVLSIASPG 759
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|34328286|ref|NP_075863.2| succinate dehydrogenase
complex, subunit B, iron sulfur (Ip) [Mus musculus]
         (282 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

18125                                                                 124   1e-35
>18125
          Length = 474

 Score =  124 bits (311), Expect(2) = 1e-35,   Method: Compositional matrix adjust.
 Identities = 55/72 (76%), Positives = 65/72 (90%)
 Frame = -1

Query: 209 LGPAVLMQAYRWMIDSRDDFTEERLAKLQDPFSVYRCHTIMNCTQTCPKGLNPGKAIAEI 268
           LGPAVLMQAYRW+IDSRD+ + ERL+KL+DPFSVYRCHTIMNCT+TCPKGLNPG+AIAEI
Sbjct: 411 LGPAVLMQAYRWIIDSRDENSVERLSKLKDPFSVYRCHTIMNCTRTCPKGLNPGRAIAEI 232

Query: 269 KKMMATYKEKRA 280
           KK+++    K A
Sbjct: 231 KKLLSGLASKPA 196

 Score = 43.1 bits (100), Expect(2) = 1e-35,   Method: Compositional matrix adjust.
 Identities = 16/20 (80%), Positives = 19/20 (95%)
 Frame = -2

Query: 189 ILCACCSTSCPSYWWNGDKY 208
           ILCACCST+CPSYWWN ++Y
Sbjct: 470 ILCACCSTACPSYWWNAEQY 411
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6755114|ref|NP_036151.1| peroxiredoxin 5 precursor
[Mus musculus]
         (210 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

29947                                                                 119   1e-35
24955                                                                  94   1e-34
18791                                                                  56   1e-11
21920                                                                  30   0.97 
05098                                                                  29   1.2  
>29947
          Length = 629

 Score =  119 bits (298), Expect(2) = 1e-35,   Method: Compositional matrix adjust.
 Identities = 63/120 (52%), Positives = 80/120 (66%)
 Frame = +2

Query: 38  GARSFSSSAVTMAPIKVGDAIPSVEVFEGEPGKKVNLAELFKGKKGVLFGVPGAFTPGCS 97
           G  S   + V   P+K GD +PSV+++EG+P  KV ++EL KGK  V+FGVPGAFTP C+
Sbjct: 35  GLLSRQLTHVANMPLKEGDKLPSVDLYEGDPNTKVKVSEL-KGKV-VIFGVPGAFTPTCN 208

Query: 98  KTHLPGFVEQAGALKAKGAQVVACLSVNDVFVIEEWGRAHQAEGKVRLLADPTGAFGKAT 157
           K H PGF+    ALKAKG   + CLSVND FV+  WG + +A GKVR LAD  G F K +
Sbjct: 209 KDHAPGFISNFDALKAKGVSEIVCLSVNDPFVMGAWGESLKAAGKVRFLADTCGEFVKKS 388

 Score = 47.8 bits (112), Expect(2) = 1e-35,   Method: Compositional matrix adjust.
 Identities = 21/37 (56%), Positives = 29/37 (78%)
 Frame = +1

Query: 174 LKRFSMVIDNGIVKALNVEPDGTGLTCSLAPNILSQL 210
           LKRF +V ++G+VK ++VEPDGTGLTCS   +I+  L
Sbjct: 433 LKRFVLVAEDGVVKGISVEPDGTGLTCSRPADIMKLL 543
>24955
          Length = 1091

 Score = 94.0 bits (232), Expect(2) = 1e-34,   Method: Compositional matrix adjust.
 Identities = 47/84 (55%), Positives = 60/84 (71%)
 Frame = -2

Query: 45   SAVTMAPIKVGDAIPSVEVFEGEPGKKVNLAELFKGKKGVLFGVPGAFTPGCSKTHLPGF 104
            + V   P+K GD +PSV+++EG+P  KV ++EL KGK  V+FGVPGAFTP C+K H PGF
Sbjct: 1027 THVANMPLKGGDKLPSVDLYEGDPNTKVKVSEL-KGKV-VIFGVPGAFTPTCNKDHAPGF 854

Query: 105  VEQAGALKAKGAQVVACLSVNDVF 128
            +    ALKAKG   + CLSVND F
Sbjct: 853  ISNFDALKAKGVSEIVCLSVNDPF 782

 Score = 69.3 bits (168), Expect(2) = 1e-34,   Method: Compositional matrix adjust.
 Identities = 37/83 (44%), Positives = 49/83 (59%)
 Frame = -3

Query: 128 FVIEEWGRAHQAEGKVRLLADPTGAFGKATXXXXXXXXXXXFGNRRLKRFSMVIDNGIVK 187
           FV+  WG + +A GKVR LAD  G F K              G+ R KRF +V ++G+VK
Sbjct: 783 FVMGAWGESLKAAGKVRFLADTCGEFVKKADLSVDLSDV--LGSVRSKRFVLVAEDGVVK 610

Query: 188 ALNVEPDGTGLTCSLAPNILSQL 210
            ++VEPDGTGLTCS   +I+  L
Sbjct: 609 GISVEPDGTGLTCSRPADIMKLL 541
>18791
          Length = 461

 Score = 56.2 bits (134), Expect(2) = 1e-11,   Method: Compositional matrix adjust.
 Identities = 34/78 (43%), Positives = 41/78 (52%)
 Frame = -1

Query: 133 WGRAHQAEGKVRLLADPTGAFGKATXXXXXXXXXXXFGNRRLKRFSMVIDNGIVKALNVE 192
           WG    A GKVR LAD    F K              GN R KRF +V ++G+VK +NVE
Sbjct: 341 WG----AAGKVRFLADTCADFVK--QAELSLDATGILGNVRSKRFVLVAEDGVVKGINVE 180

Query: 193 PDGTGLTCSLAPNILSQL 210
           PD  G +CS A + LS L
Sbjct: 179 PDSIGYSCSKAQDALSFL 126

 Score = 29.6 bits (65), Expect(2) = 1e-11,   Method: Compositional matrix adjust.
 Identities = 12/29 (41%), Positives = 18/29 (62%)
 Frame = -2

Query: 103 GFVEQAGALKAKGAQVVACLSVNDVFVIE 131
            F++   A + KG   + CLSVND FV++
Sbjct: 442 NFIQNVEAREGKGVSSIVCLSVNDPFVMD 356
>21920
          Length = 722

 Score = 29.6 bits (65), Expect = 0.97,   Method: Compositional matrix adjust.
 Identities = 28/119 (23%), Positives = 46/119 (38%), Gaps = 5/119 (4%)
 Frame = -3

Query: 20  STCLAGRAGRKEAGWECGGARSFSSSAVTMAPIKVGDAIPSVEVFEGEPGKKVNLAELFK 79
           +T    + GR+E GW CG  R   + +    P+      PS+ +   E   + +  E   
Sbjct: 546 ATMTTAKTGRRE-GWCCGQLRERHTGSDVPCPVMTSPCSPSLPLASPERAGRHHAQEQHD 370

Query: 80  GKKGV----LFGVPGAFTPGCSKTHLPGFVEQAGALKAKGAQVVACL-SVNDVFVIEEW 133
                       VPG+     S +H P F+ +  AL  +G     CL S + +   + W
Sbjct: 369 RHNTQACTGTRAVPGS---SLSLSHFPPFLYRHLALYPRGPHF--CLRSSSHLLGADNW 208
>05098
          Length = 1035

 Score = 29.3 bits (64), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 15/50 (30%), Positives = 24/50 (48%)
 Frame = -2

Query: 83  GVLFGVPGAFTPGCSKTHLPGFVEQAGALKAKGAQVVACLSVNDVFVIEE 132
           G +FG+ GAF PG S  HLP   +       +   V+  + VN +  + +
Sbjct: 761 GNIFGMAGAFXPGLSLIHLPAH-QATNVFAWR*VGVLMSMRVNXILNVSK 615
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6755668|ref|NP_035614.1| signal transducing adaptor
molecule (SH3 domain and ITAM motif) 1 [Mus musculus]
         (548 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

30899                                                                 147   1e-35
30964                                                                  72   7e-13
16716                                                                  60   3e-09
12324                                                                  59   6e-09
17286                                                                  56   3e-08
01494                                                                  50   3e-06
29687                                                                  46   5e-05
20131                                                                  44   1e-04
15115                                                                  44   2e-04
26032                                                                  44   2e-04
13664                                                                  42   5e-04
29243                                                                  40   0.003
33143                                                                  35   0.084
31183                                                                  35   0.10 
30740                                                                  32   0.90 
21187                                                                  30   1.7  
18881                                                                  29   4.5  
>30899
          Length = 698

 Score =  147 bits (370), Expect = 1e-35,   Method: Compositional matrix adjust.
 Identities = 66/101 (65%), Positives = 84/101 (83%), Gaps = 1/101 (0%)
 Frame = -3

Query: 1   MPLFA-TNPFDQDVEKATSELNTAEDWGLILDICDKVGQSRTGPKDCLRSIMRRVNHKDP 59
           MPLFA T+PFD DVEKAT E++T+EDWGLILDIC+KVG+ + G +DCL+SI++R+NHK P
Sbjct: 693 MPLFAATSPFDVDVEKATHEMSTSEDWGLILDICEKVGRQQNGARDCLKSIVKRLNHKVP 514

Query: 60  HVAMQALTLLGACVSNCGKIFHLEVCSRDFASEVSNVLNKG 100
            VAMQALTLL ACV+NCG+ FHLE+CSRD    V++   +G
Sbjct: 513 FVAMQALTLLDACVNNCGRQFHLEICSRDLPQNVAHSSTRG 391

 Score =  103 bits (256), Expect = 2e-22,   Method: Compositional matrix adjust.
 Identities = 72/157 (45%), Positives = 95/157 (60%), Gaps = 12/157 (7%)
 Frame = -2

Query: 89  FASEVSNVLN-KGHPKVCEKLKALMVEWTD--EFKNDPQLSLISAMIKNLKEQGVTF--P 143
           F SE   ++N + HPKV +KLK L+  W++  EFK+D  LSLI A+ ++LK++G  F  P
Sbjct: 427 FTSECRTLINQRAHPKVAQKLKHLIKRWSELPEFKDDAALSLIPALYESLKKEGADFADP 248

Query: 144 AIGSQAAEQAKASPALVAKDPGTVATKKEEEDLAKAIELSLK--EQRQQSA-----PVST 196
             G +    A    A VA+         EE+D+AKAI LSLK  E+ Q  A     PVS 
Sbjct: 247 DSGPKKTTDA----AQVAR---------EEDDIAKAIALSLKDAEKSQPKASGSLYPVS- 110

Query: 197 LYPSTSNLLTNHQHEGRKVRAVYDFEAAEDNELTFKA 233
            YP+ ++   N   E RKVRA+YDFEAAEDNELTF+A
Sbjct: 109 -YPTMADTTYNKPKELRKVRALYDFEAAEDNELTFQA 2
>30964
          Length = 894

 Score = 71.6 bits (174), Expect = 7e-13,   Method: Compositional matrix adjust.
 Identities = 38/108 (35%), Positives = 60/108 (55%), Gaps = 6/108 (5%)
 Frame = -1

Query: 42  GPKDCLRSIMRRVNH---KDPHVAMQALTLLGACVSNCGKIFHLEVCSRDFASEVSNVLN 98
           GPKD  R+  +R++    K+    M  LT L  CV NCG+ FH+ V ++DF  E+  V+ 
Sbjct: 855 GPKDASRAFKKRLSQNVGKNFTAIMYTLTCLETCVKNCGRRFHVCVATKDFLQELVKVIG 676

Query: 99  KGH--PK-VCEKLKALMVEWTDEFKNDPQLSLISAMIKNLKEQGVTFP 143
             H  P+ V EK+  ++  W D F+  P+L  +  + + LK +G+ FP
Sbjct: 675 PKHDPPQAVQEKVLQMIQTWADAFRGAPELKEVEKIYQELKSKGIEFP 532
>16716
          Length = 934

 Score = 59.7 bits (143), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 23/48 (47%), Positives = 35/48 (72%)
 Frame = -1

Query: 217 AVYDFEAAEDNELTFKAGEIITVLDDSDPNWWKGETHQGVGLFPSNFV 264
           A+YD++AA+D+ELTF   ++IT ++  D  WW+G  H   GLFP+N+V
Sbjct: 457 ALYDYQAADDDELTFDPDDVITDIEMIDDGWWRGSCHGKNGLFPANYV 314
>12324
          Length = 946

 Score = 58.5 bits (140), Expect = 6e-09,   Method: Compositional matrix adjust.
 Identities = 25/51 (49%), Positives = 34/51 (66%)
 Frame = +3

Query: 214 KVRAVYDFEAAEDNELTFKAGEIITVLDDSDPNWWKGETHQGVGLFPSNFV 264
           KV A+YD+EA +D+ELTF    +I V+  +D  WW+G      GLFPSN+V
Sbjct: 693 KVVAIYDYEAEKDDELTFSENSVIYVIRKNDDGWWEGVMDGVTGLFPSNYV 845
>17286
          Length = 489

 Score = 56.2 bits (134), Expect = 3e-08,   Method: Composition-based stats.
 Identities = 23/49 (46%), Positives = 32/49 (65%)
 Frame = +3

Query: 216 RAVYDFEAAEDNELTFKAGEIITVLDDSDPNWWKGETHQGVGLFPSNFV 264
           RA+YDF    D EL F+ G++IT++   D NW++G  H  VG FP N+V
Sbjct: 33  RAIYDFLPESDGELGFQEGDMITLISQVDENWFEGSVHGKVGYFPINYV 179
>01494
          Length = 2122

 Score = 49.7 bits (117), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 22/52 (42%), Positives = 33/52 (63%), Gaps = 1/52 (1%)
 Frame = +3

Query: 214 KVRAVYDFEAAEDNELTFKAGEIITVLDDSDPNWWKGETH-QGVGLFPSNFV 264
           +V+A++D+ A  D+EL+F  G IIT +   D  WW+G+   +    FPSNFV
Sbjct: 309 RVKALHDYNANRDDELSFCKGAIITNVSRQDGGWWRGDYGAKKQHWFPSNFV 464
>29687
          Length = 434

 Score = 45.8 bits (107), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 20/52 (38%), Positives = 33/52 (63%), Gaps = 1/52 (1%)
 Frame = -2

Query: 214 KVRAVYDFEAAEDNELTFKAGEIITVLDDSDPNWWKGETH-QGVGLFPSNFV 264
           +V+A++D+ A  ++EL+F  G IIT +   D  WW+G+   +    FPSN+V
Sbjct: 295 RVKALHDYNAKREDELSFCKGAIITNVSRQDGGWWRGDYGTKKQHWFPSNYV 140
>20131
          Length = 574

 Score = 44.3 bits (103), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 20/56 (35%), Positives = 31/56 (55%)
 Frame = -2

Query: 209 QHEGRKVRAVYDFEAAEDNELTFKAGEIITVLDDSDPNWWKGETHQGVGLFPSNFV 264
           + EG    A+Y + + E  +LTF  G++I V    D +WW G   +  G+FPS +V
Sbjct: 492 RKEGEYYVAMYSYVSGETADLTFNEGDMILVTKK-DEDWWTGTLGEKTGMFPSTYV 328
>15115
          Length = 443

 Score = 43.5 bits (101), Expect = 2e-04,   Method: Composition-based stats.
 Identities = 19/44 (43%), Positives = 28/44 (63%), Gaps = 1/44 (2%)
 Frame = -2

Query: 222 EAAEDNELTFKAGEIITVLDDSDPNWWKGETHQG-VGLFPSNFV 264
           +A +D E+TF   +IIT +D  D  WW+G    G  G+FP+N+V
Sbjct: 430 QAGDDTEITFDPDDIITNIDQIDEGWWQGFAPDGSYGMFPANYV 299
>26032
          Length = 465

 Score = 43.5 bits (101), Expect = 2e-04,   Method: Composition-based stats.
 Identities = 19/45 (42%), Positives = 28/45 (62%)
 Frame = +2

Query: 220 DFEAAEDNELTFKAGEIITVLDDSDPNWWKGETHQGVGLFPSNFV 264
           DFE  +D+EL F+  +IIT++   D + W GE +   G FP+ FV
Sbjct: 29  DFERHDDDELGFRKNDIITLISQKDEHCWIGELNGLRGWFPAKFV 163
>13664
          Length = 507

 Score = 42.4 bits (98), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 17/43 (39%), Positives = 27/43 (62%)
 Frame = +2

Query: 213 RKVRAVYDFEAAEDNELTFKAGEIITVLDDSDPNWWKGETHQG 255
           +KV A+YD++A   +ELT  +G++I +L     +WW GE   G
Sbjct: 365 KKVVALYDYKAQRSDELTILSGDVIMLLHKDSESWWMGELLDG 493
>29243
          Length = 1147

 Score = 39.7 bits (91), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 20/52 (38%), Positives = 29/52 (55%), Gaps = 4/52 (7%)
 Frame = +2

Query: 217 AVYDFEAAEDNELTFKAGEIITVL--DDSDPNWWKGET--HQGVGLFPSNFV 264
           AVYD+ A   ++L+ K  + I +L  +  D  WWKGE    Q +G FP  +V
Sbjct: 644 AVYDYAATSTSQLSMKLNDRIAILSKNGQDKGWWKGENLRTQKIGYFPLAYV 799

 Score = 32.0 bits (71), Expect = 0.71,   Method: Compositional matrix adjust.
 Identities = 12/37 (32%), Positives = 20/37 (54%)
 Frame = +3

Query: 229 LTFKAGEIITVLDDSDPNWWKGETHQGVGLFPSNFVT 265
           L F    ++ V+ D+D  W +G  +   G FPS++V 
Sbjct: 54  LCFDKDHVVDVISDADTEWCRGRFNGEEGYFPSSYVV 164
>33143
          Length = 1469

 Score = 35.0 bits (79), Expect = 0.084,   Method: Compositional matrix adjust.
 Identities = 15/51 (29%), Positives = 28/51 (54%), Gaps = 3/51 (5%)
 Frame = -2

Query: 217 AVYDFEAAEDNELTFKAGEIITVLD---DSDPNWWKGETHQGVGLFPSNFV 264
           AV  + A   +E++ + G+ ++V+D        WW+G+    VG FP++ V
Sbjct: 424 AVKPYAAHASDEISLQVGDFVSVIDMPSSEGTKWWRGKKGFEVGFFPADCV 272
>31183
          Length = 923

 Score = 34.7 bits (78), Expect = 0.10,   Method: Compositional matrix adjust.
 Identities = 13/30 (43%), Positives = 20/30 (66%)
 Frame = +1

Query: 235 EIITVLDDSDPNWWKGETHQGVGLFPSNFV 264
           ++IT ++  D  WW+G  H   GLFP+N+V
Sbjct: 4   DVITDIEMIDDGWWRGSCHGKNGLFPANYV 93
>30740
          Length = 488

 Score = 31.6 bits (70), Expect = 0.90,   Method: Composition-based stats.
 Identities = 15/58 (25%), Positives = 25/58 (43%)
 Frame = +2

Query: 198 YPSTSNLLTNHQHEGRKVRAVYDFEAAEDNELTFKAGEIITVLDDSDPNWWKGETHQG 255
           Y  T+ L+     E  K+   YDF   +  +L F  G+I+ ++   +  WW      G
Sbjct: 146 YLDTTTLIRPAPRE--KLMGKYDFSGRDPEDLPFSKGDILELISKDEEEWWTARDKHG 313
>21187
          Length = 1206

 Score = 30.4 bits (67), Expect = 1.7,   Method: Compositional matrix adjust.
 Identities = 17/54 (31%), Positives = 25/54 (46%), Gaps = 3/54 (5%)
 Frame = +2

Query: 214 KVRAVYDFEAAEDNELTFKAGEIITVLDDS---DPNWWKGETHQGVGLFPSNFV 264
           K  A+  + A+    LT   G+I+ +   S    P+ W GE +   G FP  FV
Sbjct: 128 KATAIGRYPASSPLYLTLNRGDIVEIKSKSAGNRPDLWGGEVNGRKGYFPKAFV 289
>18881
          Length = 762

 Score = 29.3 bits (64), Expect = 4.5,   Method: Compositional matrix adjust.
 Identities = 15/41 (36%), Positives = 23/41 (56%), Gaps = 4/41 (9%)
 Frame = -3

Query: 228 ELTFKAGEIITVL--DDSDPNWWKGET--HQGVGLFPSNFV 264
           ++T K  + I++L  +  D  WWKGE    + VG FP  +V
Sbjct: 439 QVTLKLNDRISILSKNGQDKGWWKGENLRTKKVGYFPLAYV 317
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|160333840|ref|NP_079803.2| signal recognition
particle 19 [Mus musculus]
         (144 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

16777                                                                 143   2e-35
11526                                                                  27   2.3  
15021                                                                  26   4.8  
>16777
          Length = 1071

 Score =  143 bits (361), Expect = 2e-35,   Method: Compositional matrix adjust.
 Identities = 65/110 (59%), Positives = 92/110 (83%), Gaps = 1/110 (0%)
 Frame = +3

Query: 10  ADQDRFICIYPAYLNNKKTIAEGRRIPISKAVENPTATEIQDVCSAVGLNAFLEKNKMYS 69
           AD++R++CIYPAY+N++KT+ EGRRIP  KAV+NP+ TE++DVC+A G+   +E NK YS
Sbjct: 84  ADRERWVCIYPAYINSRKTVKEGRRIPKEKAVDNPSYTEVRDVCAAAGMVLGVE-NKTYS 260

Query: 70  REWN-RDVQFRGRVRVQLKQEDGSLCLVQFPSRKSVMLYVAEMIPKLKTR 118
           RE + RD++FRGR+RVQLK+EDGS+ +  FP++K V+LY+ E IPKLK+R
Sbjct: 261 RELDARDLKFRGRIRVQLKKEDGSVMMEHFPTKKXVLLYLGETIPKLKSR 410
>11526
          Length = 575

 Score = 27.3 bits (59), Expect = 2.3,   Method: Compositional matrix adjust.
 Identities = 13/31 (41%), Positives = 18/31 (58%)
 Frame = +3

Query: 5   AARSPADQDRFICIYPAYLNNKKTIAEGRRI 35
             ++  DQ R ICIY    NNK T  EG+++
Sbjct: 474 TTKNTPDQSRSICIYCCCENNKTT--EGKKM 560
>15021
          Length = 572

 Score = 26.2 bits (56), Expect = 4.8,   Method: Compositional matrix adjust.
 Identities = 14/56 (25%), Positives = 29/56 (51%), Gaps = 5/56 (8%)
 Frame = -1

Query: 11  DQDRFIC-----IYPAYLNNKKTIAEGRRIPISKAVENPTATEIQDVCSAVGLNAF 61
           ++D  +C     ++P+++N+K  +     +PI +  ++    E+  VC  VG  AF
Sbjct: 542 EKDLMLCDCPGLVFPSFVNSKAELVVNGILPIDQLQDSEPPVEL--VCHRVGRRAF 381
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31543940|ref|NP_062780.2| vesicle-associated membrane
protein, associated protein B and C [Mus musculus]
         (243 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

34509                                                                 145   2e-35
11078                                                                  28   4.7  
>34509
          Length = 408

 Score =  145 bits (365), Expect = 2e-35,   Method: Compositional matrix adjust.
 Identities = 64/94 (68%), Positives = 77/94 (81%)
 Frame = +2

Query: 1   MAKVEQVLSLEPQHELKFRGPFTDVVTTNLKLGNPTDRNVCFKVKTTAPRRYCVRPNSGV 60
           M+K EQ L L+P  EL F+GPFTD VT  LKL NPT++ +CFKVKTTAP+RYCVRPNSG+
Sbjct: 80  MSKTEQALVLDPATELVFKGPFTDTVTAVLKLQNPTEKKICFKVKTTAPKRYCVRPNSGI 259

Query: 61  IDAGASLNVSVMLQPFDYDPNEKSKHKFMVQSMF 94
           +D   + +V VMLQPF+YDP+EKSKHKFMVQSM 
Sbjct: 260 LDPNGTASVQVMLQPFEYDPSEKSKHKFMVQSML 361
>11078
          Length = 469

 Score = 27.7 bits (60), Expect = 4.7,   Method: Compositional matrix adjust.
 Identities = 12/23 (52%), Positives = 16/23 (69%)
 Frame = +1

Query: 1   MAKVEQVLSLEPQHELKFRGPFT 23
           M+K EQ L L+P  EL+F+G  T
Sbjct: 319 MSKTEQALVLDPPTELQFKGKMT 387
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|8393784|ref|NP_059076.1| septin 9 isoform c [Mus
musculus]
         (334 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

14132                                                                 145   2e-35
14677                                                                  89   1e-21
34156                                                                  87   1e-17
22078                                                                  69   3e-12
29788                                                                  67   1e-11
38061                                                                  30   1.2  
07633                                                                  30   1.6  
32946                                                                  29   2.4  
32225                                                                  28   6.2  
>14132
          Length = 422

 Score =  145 bits (366), Expect = 2e-35,   Method: Compositional matrix adjust.
 Identities = 71/140 (50%), Positives = 98/140 (70%), Gaps = 2/140 (1%)
 Frame = -2

Query: 115 FGDHINNENCWQPIMKFINDQYEKYLQEEVNINRKKRIPDTRVHCCLYFIPATGHSLRPL 174
           FGD ++N NCWQPI  +I+ +YE+YL  E  +NR   +PDTRVHCCLYFI  TGH L+PL
Sbjct: 421 FGDAVDNSNCWQPITDYIDSKYEEYLNAESRVNRTV-MPDTRVHCCLYFIAPTGHGLKPL 245

Query: 175 DIEFMKRLSKVVNIVPVIAKADTLTLEERVYFKQRITADLLSNGIDVYPQKEFDEDAEDR 234
           D+EFMKRL   VNI+P++AKADTLT +E   FK+ I  ++  + I +Y   + D D E+ 
Sbjct: 244 DVEFMKRLHDKVNIIPLVAKADTLTPDECREFKKTILNEIAQHKIKIYEFPDCD-DEEEM 68

Query: 235 LVNEKFR--EMIPFAVVGSD 252
            + ++ R  + +PFAVVGS+
Sbjct: 67  KIQKRLRVSDRVPFAVVGSN 8
>14677
          Length = 378

 Score = 89.4 bits (220), Expect(2) = 1e-21,   Method: Compositional matrix adjust.
 Identities = 38/76 (50%), Positives = 55/76 (72%), Gaps = 1/76 (1%)
 Frame = -1

Query: 89  IEIKSITHDIEEKGVRMKLTVIDTPGFGDHINNENCWQPIMKFINDQYEKYLQEEVNINR 148
           +++K+ T+D+ EK VR+KLT +DT GFGD IN  + W+PI+ +I+ Q++ YLQEE+ I R
Sbjct: 228 VKLKAHTYDLTEKNVRLKLTTVDTTGFGDQINKADSWKPIVDYIDAQFDAYLQEELKIKR 49

Query: 149 K-KRIPDTRVHCCLYF 163
                 D+RVH CLYF
Sbjct: 48  MLHSYHDSRVHACLYF 1

 Score = 31.2 bits (69), Expect(2) = 1e-21,   Method: Compositional matrix adjust.
 Identities = 15/40 (37%), Positives = 25/40 (62%)
 Frame = -3

Query: 31  DSILEQMRRKAMKQGFEFNIMVVGQSGLGKSTLINTLFKS 70
           D ++  +  KA    F     V+G++G+GKSTL++TLF +
Sbjct: 376 DQLVTSLSLKASASTF----FVLGETGIGKSTLMDTLFNT 269
>34156
          Length = 348

 Score = 86.7 bits (213), Expect = 1e-17,   Method: Compositional matrix adjust.
 Identities = 39/77 (50%), Positives = 63/77 (81%)
 Frame = -1

Query: 36  QMRRKAMKQGFEFNIMVVGQSGLGKSTLINTLFKSKISRKSVQPTSEERIPKTIEIKSIT 95
           Q+ RK++K+GFEF +MVVG+SGLGKSTL+N+LF + +  +   P++ E+I +T++I + T
Sbjct: 231 QVHRKSVKKGFEFTLMVVGESGLGKSTLVNSLFLTDLYPERHIPSASEKIQQTVKIDAST 52

Query: 96  HDIEEKGVRMKLTVIDT 112
            +IEE+GV+++LTV+DT
Sbjct: 51  VEIEERGVKLRLTVVDT 1
>22078
          Length = 417

 Score = 68.6 bits (166), Expect = 3e-12,   Method: Compositional matrix adjust.
 Identities = 26/57 (45%), Positives = 41/57 (71%)
 Frame = +3

Query: 264 GRKTKWGTIEVENTTHCEFAYLRDLLIRTHMQNIKDITSNIHFEAYRVKRLNEGNSA 320
           GR   WG +EV+N +HC+F  LR +LI THMQ++KD+TS++H+E +R   + +  +A
Sbjct: 6   GRAYPWGIVEVDNXSHCDFIRLRQMLISTHMQDLKDVTSDVHYENFRSSFIQQSLAA 176
>29788
          Length = 687

 Score = 67.0 bits (162), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 25/46 (54%), Positives = 37/46 (80%)
 Frame = +3

Query: 269 WGTIEVENTTHCEFAYLRDLLIRTHMQNIKDITSNIHFEAYRVKRL 314
           WG +EVEN  H +F  LR++LIRTHMQ++KD+T+N+H+E +R  +L
Sbjct: 6   WGIVEVENLEHNDFIALRNMLIRTHMQDLKDVTNNVHYENFRYNKL 143
>38061
          Length = 206

 Score = 30.0 bits (66), Expect = 1.2,   Method: Composition-based stats.
 Identities = 11/26 (42%), Positives = 17/26 (65%)
 Frame = +3

Query: 244 IPFAVVGSDHEYQVNGKRILGRKTKW 269
           +PFAVVGS+ E ++  K +  R+  W
Sbjct: 129 LPFAVVGSNDEVKIGNKMVKARQGSW 206
>07633
          Length = 995

 Score = 29.6 bits (65), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 24/82 (29%), Positives = 36/82 (43%), Gaps = 3/82 (3%)
 Frame = -3

Query: 39  RKAMKQGFEFNIMVVGQSGLGKSTLINTLFKSKISRKSVQPTSEERIPKTIEIKSITHDI 98
           R  M    E  ++++G++G GKS+L NTL      R              +   S+T   
Sbjct: 939 RVNMSSSDELRVVLLGKTGSGKSSLGNTLLARSAFRVE------------LSFASVTFRC 796

Query: 99  E-EKGVR--MKLTVIDTPGFGD 117
           +   G+R  + L V DTPG  D
Sbjct: 795 QWACGLRHNVLLQVTDTPGVSD 730
>32946
          Length = 483

 Score = 29.3 bits (64), Expect = 2.4,   Method: Compositional matrix adjust.
 Identities = 15/36 (41%), Positives = 23/36 (63%)
 Frame = -3

Query: 42  MKQGFEFNIMVVGQSGLGKSTLINTLFKSKISRKSV 77
           M QG  ++   VG++G GKS+LIN LF+   +  S+
Sbjct: 400 MNQGKSWH---VGRTGAGKSSLINALFRLSYNDGSI 302
>32225
          Length = 276

 Score = 27.7 bits (60), Expect = 6.2,   Method: Compositional matrix adjust.
 Identities = 18/49 (36%), Positives = 25/49 (51%)
 Frame = -2

Query: 107 LTVIDTPGFGDHINNENCWQPIMKFINDQYEKYLQEEVNINRKKRIPDT 155
           L  ID        N E CW  I + I +  EKY+  +VN ++KK+I  T
Sbjct: 272 LNEIDWAEQMKSSNVEECWLCIKRIIQEAMEKYI-PKVNFSQKKKIKPT 129
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31542563|ref|NP_032955.2| DnaJ (Hsp40) homolog,
subfamily C, member 3B [Mus musculus]
         (504 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

21525                                                                 145   4e-35
13998                                                                  81   1e-15
07620                                                                  44   3e-06
02324                                                                  48   8e-06
14550                                                                  47   2e-05
03857                                                                  46   4e-05
04645                                                                  45   7e-05
01124                                                                  43   2e-04
22505                                                                  42   5e-04
02088                                                                  39   0.005
36227                                                                  36   0.047
26984                                                                  35   0.058
08670                                                                  34   0.11 
35264                                                                  31   1.5  
35858                                                                  30   2.8  
10994                                                                  30   2.9  
15360                                                                  28   6.1  
07784                                                                  28   7.2  
>21525
          Length = 639

 Score =  145 bits (365), Expect = 4e-35,   Method: Compositional matrix adjust.
 Identities = 77/204 (37%), Positives = 119/204 (58%)
 Frame = -3

Query: 123 EAEDDFKKVLKSNPSEQEEKEAESQLVKADEMQRLRSQALDAFDGADYTAAITFLDKILE 182
           EA+ DF+ V+K +P+     EA  +      +Q    QA   +    Y   I  L  ++E
Sbjct: 607 EAQADFQHVIKQDPNN---AEASEKFNLVGPLQHQIDQARALYSQGRYQDVINILGPVVE 437

Query: 183 VCVWDAELRELRAECFIKEGEPRKAISDLKAASKLKSDNTEAFYKISTLYYQLGDHELSL 242
            C    ELRE+RAE +++ GE  KA  +L+   K+ SDNT+ + ++S L+YQ+G+ + SL
Sbjct: 436 YCPSYTELREMRAESYVELGELGKATGELRQTVKMTSDNTKGYLRLSLLHYQMGEEDDSL 257

Query: 243 SEVRECLKLDQDHKRCFAHYKQVKKLNKLIESAEELIRDGRYTDATSKYESVMKTEPSVA 302
            ++RECLKLD DHK CFAHYK+VKKL K + SA+E     +Y +   K + ++KTE  + 
Sbjct: 256 LQIRECLKLDPDHKECFAHYKKVKKLAKQLTSADEFKNAEQYQECVDKAQQILKTESQIW 77

Query: 303 EYTVRSKERICHCFSKDEKPVEAI 326
            + +R++   C C+SK     EA+
Sbjct: 76  PFLLRTRSLFCRCYSKMGSIKEAL 5
>13998
          Length = 1075

 Score = 80.9 bits (198), Expect = 1e-15,   Method: Compositional matrix adjust.
 Identities = 63/181 (34%), Positives = 85/181 (46%), Gaps = 2/181 (1%)
 Frame = +1

Query: 325 AIRICSEVLQMEPDNVNALKDRAEAYLIEEMYDEAIQDYEAAQEHNENDQQIREGLEKAQ 384
           A+  C+ VL +    + AL  RA      E ++EA+ DYE A +  E   +I+  L  A+
Sbjct: 1   AVADCNRVLDLNSQYLKALLLRARCNNDLEKFEEAVADYETALQL-EKTPEIKRLLRDAK 177

Query: 385 RLLKQSQKRDYYKILGVKRNAKKQEIIKAYRKLALQWHPDNFQNXXXXXXXXXXXXXXX- 443
             LK+S+++DYYKILG+ RNA + EI KAYRK AL  HPD   N                
Sbjct: 178 FALKKSKRKDYYKILGISRNATEDEIKKAYRKKALVHHPDRHANSSADVRKDEELKFKEV 357

Query: 444 -XXXXVLSDPEMRKKFDDGEDPLDAESQQGGGGNPFHRSWNSWQGFNPFSSGGPFRFKFH 502
                +LSD   + ++D G D  D E Q     N   RS      F  FS G    F F 
Sbjct: 358 GEAYAILSDGAKKTRYDSGHDIQD-EMQADFDPNQMFRS------FFQFSGGRNSSFNFE 516

Query: 503 F 503
           +
Sbjct: 517 Y 519
>07620
          Length = 1775

 Score = 44.3 bits (103), Expect(2) = 3e-06,   Method: Compositional matrix adjust.
 Identities = 18/36 (50%), Positives = 28/36 (77%)
 Frame = +1

Query: 393 RDYYKILGVKRNAKKQEIIKAYRKLALQWHPDNFQN 428
           +DYY++L VK++  + ++ KAYRKLALQ HPD  ++
Sbjct: 97  KDYYEVLDVKKDCTESDMKKAYRKLALQMHPDKTRH 204

 Score = 25.0 bits (53), Expect(2) = 3e-06,   Method: Compositional matrix adjust.
 Identities = 18/52 (34%), Positives = 25/52 (48%), Gaps = 4/52 (7%)
 Frame = +3

Query: 448 VLSDPEMRKKFD----DGEDPLDAESQQGGGGNPFHRSWNSWQGFNPFSSGG 495
           VLSDP+ R+K+D    + + P    S+   GG  F       + FN F  GG
Sbjct: 249 VLSDPDKRRKYDVYGPELQQPSQHHSEYSNGG--FEGDITPEELFNMFFGGG 398
>02324
          Length = 2058

 Score = 48.1 bits (113), Expect = 8e-06,   Method: Compositional matrix adjust.
 Identities = 33/105 (31%), Positives = 52/105 (49%)
 Frame = +2

Query: 390 SQKRDYYKILGVKRNAKKQEIIKAYRKLALQWHPDNFQNXXXXXXXXXXXXXXXXXXXVL 449
           S+ R +Y++LGV+R+A   ++ KAYRKLAL++HPD  +N                   +L
Sbjct: 92  SKIRCHYEVLGVERSADNDDLKKAYRKLALKFHPD--KNPDSVEEATAQFRLVQQAYEIL 265

Query: 450 SDPEMRKKFDDGEDPLDAESQQGGGGNPFHRSWNSWQGFNPFSSG 494
           +DP+ R  +D   + +     +GG G       NS   F  F+S 
Sbjct: 266 TDPQERSWYDRHREAI----LRGGQGKGDKYEDNSLNLFQYFTSS 388
>14550
          Length = 1395

 Score = 47.0 bits (110), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 33/86 (38%), Positives = 46/86 (53%), Gaps = 1/86 (1%)
 Frame = -1

Query: 393  RDYYKILGVKRNAKKQEIIKAYRKLALQWHPDNFQNXXXXXXXXXXXXXXXXXXXVLSDP 452
            RD+YKILGV ++A  ++I +AYRK+A + HPD  ++                   VLSD 
Sbjct: 1137 RDFYKILGVSKSADTKQIKRAYRKIAKELHPDKNRD---DPEAEQRFQDLGAAYEVLSDE 967

Query: 453  EMRKKFD-DGEDPLDAESQQGGGGNP 477
            E RK +D  GE+ L    Q   GG+P
Sbjct: 966  EKRKVYDRHGEEGL---KQGDMGGDP 898
>03857
          Length = 1696

 Score = 45.8 bits (107), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 33/137 (24%), Positives = 68/137 (49%), Gaps = 15/137 (10%)
 Frame = +1

Query: 273 ESAEELIRDGRYTDATSKYESVMK------TEPSVAEYTVRSKERICH---------CFS 317
           ++   L + G++  A  KY+  ++       E  ++E   ++ E+  H         C  
Sbjct: 478 QAGNTLFKAGKFGPANRKYKKALRYLQKLDEEQKMSEDQQKAMEKELHIPVSLNAAACCL 657

Query: 318 KDEKPVEAIRICSEVLQMEPDNVNALKDRAEAYLIEEMYDEAIQDYEAAQEHNENDQQIR 377
           K  K  EA+  C EVL+ +PDN  A   + +A+   + Y+ A+  ++ A   N +D+ I+
Sbjct: 658 KLNKYNEALEYCQEVLEADPDNSKAQYRQGQAHAGNKDYETALASFQKALAANPDDKGIK 837

Query: 378 EGLEKAQRLLKQSQKRD 394
             ++K +R +++ +KR+
Sbjct: 838 LEIQKVKRTVEEEKKRE 888
>04645
          Length = 1075

 Score = 45.1 bits (105), Expect = 7e-05,   Method: Compositional matrix adjust.
 Identities = 40/161 (24%), Positives = 66/161 (40%)
 Frame = +3

Query: 152 DEMQRLRSQALDAFDGADYTAAITFLDKILEVCVWDAELRELRAECFIKEGEPRKAISDL 211
           D+    R+QA+DA        AI F    ++     A L   R   ++K G+P+KAI D 
Sbjct: 438 DQASDNRNQAMDAMAEGRLEDAIGFFTDAIKSNPTSALLYAKRGSAYLKMGKPKKAIHDC 617

Query: 212 KAASKLKSDNTEAFYKISTLYYQLGDHELSLSEVRECLKLDQDHKRCFAHYKQVKKLNKL 271
             A +L  D+ + +      +  LG  E S  ++    KLD D     A +       K+
Sbjct: 618 SKAIELNPDSAQGYKWRGKAHKLLGHWEESYHDLTLACKLDYDDDANTALHDVTANAKKI 797

Query: 272 IESAEELIRDGRYTDATSKYESVMKTEPSVAEYTVRSKERI 312
           +E   +  R     + T + E + K      EY  + + R+
Sbjct: 798 MEHKRKYERQQEERELTKRKERIRKAR---EEYEKQKRSRV 911

 Score = 37.0 bits (84), Expect = 0.019,   Method: Compositional matrix adjust.
 Identities = 25/93 (26%), Positives = 45/93 (48%), Gaps = 1/93 (1%)
 Frame = +3

Query: 275 AEELIRDGRYTDATSKYESVMKTEPSVAE-YTVRSKERICHCFSKDEKPVEAIRICSEVL 333
           A + + +GR  DA   +   +K+ P+ A  Y  R        + K  KP +AI  CS+ +
Sbjct: 465 AMDAMAEGRLEDAIGFFTDAIKSNPTSALLYAKRGS-----AYLKMGKPKKAIHDCSKAI 629

Query: 334 QMEPDNVNALKDRAEAYLIEEMYDEAIQDYEAA 366
           ++ PD+    K R +A+ +   ++E+  D   A
Sbjct: 630 ELNPDSAQGYKWRGKAHKLLGHWEESYHDLTLA 728
>01124
          Length = 1372

 Score = 43.1 bits (100), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 35/117 (29%), Positives = 58/117 (49%), Gaps = 8/117 (6%)
 Frame = -3

Query: 282 GRYTDATSKYESVMKTEPSVAEYTVRSKERICHCFSKDEKPVEAIRICSEVLQM----EP 337
           G Y  A + Y   ++  P +   ++ S    CH   K     + I  CS+ + +     P
Sbjct: 713 GNYQAAVNVYTHALRLNPKMP--SLYSNRAACHL--KLRNLFKCIEDCSKAMDLLSPPVP 546

Query: 338 DN----VNALKDRAEAYLIEEMYDEAIQDYEAAQEHNENDQQIREGLEKAQRLLKQS 390
            N    V A+  R  A+   EMY E +QDYEAA + + N+QQ++E  EK +++++ S
Sbjct: 545 QNAASRVKAMVRRGTAFCQLEMYVEGLQDYEAALKLDPNNQQLKEDAEKMRQIIQGS 375
>22505
          Length = 784

 Score = 42.0 bits (97), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 20/37 (54%), Positives = 25/37 (67%)
 Frame = -1

Query: 392 KRDYYKILGVKRNAKKQEIIKAYRKLALQWHPDNFQN 428
           K D Y ILGV   A +++I+KAYRK AL+ HPD  Q 
Sbjct: 658 KMDLYGILGVGPEANEKQIVKAYRKKALKCHPDKTQT 548
>02088
          Length = 1062

 Score = 38.9 bits (89), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 20/67 (29%), Positives = 32/67 (47%)
 Frame = +3

Query: 394 DYYKILGVKRNAKKQEIIKAYRKLALQWHPDNFQNXXXXXXXXXXXXXXXXXXXVLSDPE 453
           D Y+++G++R A  QE+ K Y K++L  HPD   +                   VLSD +
Sbjct: 108 DLYEVIGIRREATPQEVKKGYHKVSLAVHPDQV-SAAEKETATRKFQTLGKVYTVLSDKD 284

Query: 454 MRKKFDD 460
            R  +D+
Sbjct: 285 KRAXYDE 305
>36227
          Length = 330

 Score = 35.8 bits (81), Expect = 0.047,   Method: Compositional matrix adjust.
 Identities = 21/36 (58%), Positives = 24/36 (66%), Gaps = 2/36 (5%)
 Frame = -1

Query: 462 EDPLDAESQQGGG--GNPFHRSWNSWQGFNPFSSGG 495
           E PLD E QQG G  G+PF++     QGFNPF SGG
Sbjct: 228 EGPLDPEQQQGNGFGGHPFYQ-----QGFNPFGSGG 136
>26984
          Length = 1107

 Score = 35.4 bits (80), Expect = 0.058,   Method: Compositional matrix adjust.
 Identities = 22/79 (27%), Positives = 38/79 (48%)
 Frame = -2

Query: 381 EKAQRLLKQSQKRDYYKILGVKRNAKKQEIIKAYRKLALQWHPDNFQNXXXXXXXXXXXX 440
           E+A + L   + +D Y ILG++ +A  ++I + YR+ A+  HPD  Q             
Sbjct: 554 EEAMKRLLACKGKDPYSILGLRADASDEDIKRYYRRQAVLVHPDKNQE----PGAEEAFK 387

Query: 441 XXXXXXXVLSDPEMRKKFD 459
                  ++ DP  RK++D
Sbjct: 386 ILGHAFEMIGDPTKRKEYD 330
>08670
          Length = 1307

 Score = 34.3 bits (77), Expect = 0.11,   Method: Compositional matrix adjust.
 Identities = 22/74 (29%), Positives = 35/74 (47%)
 Frame = +3

Query: 60  FHAAVDGDPDNYIAYYRRATVFLAMGKSKAALPDLTKVIALKMDFTAARLQRGHLLLKQG 119
           F  A+  DP ++     R+  +  + + + AL D  K I L  D+     ++G  L    
Sbjct: 441 FTEAIALDPKDFRFLGNRSYCYDRLQQYEKALKDAEKAIKLSKDWPKGYFRKGRALAGLC 620

Query: 120 KLDEAEDDFKKVLK 133
           K  EAE+ F +VLK
Sbjct: 621 KFSEAEESFLQVLK 662
>35264
          Length = 867

 Score = 30.8 bits (68), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 19/66 (28%), Positives = 33/66 (50%), Gaps = 1/66 (1%)
 Frame = +2

Query: 221 NTEAFY-KISTLYYQLGDHELSLSEVRECLKLDQDHKRCFAHYKQVKKLNKLIESAEELI 279
           N +A Y +  ++YYQ  + E +    +  L+L  DH +    +++ K+L    ES     
Sbjct: 581 NADAVYVRGLSMYYQ-DNTEKAFQHFQHALRLAPDHTKARDAFRKAKQLTAQKESGNAAF 757

Query: 280 RDGRYT 285
           R+GR T
Sbjct: 758 REGRLT 775
>35858
          Length = 642

 Score = 29.6 bits (65), Expect = 2.8,   Method: Compositional matrix adjust.
 Identities = 28/114 (24%), Positives = 53/114 (46%), Gaps = 5/114 (4%)
 Frame = +2

Query: 106 AARLQRGHLLLKQGKLDEAEDDFKKVLKSNPSEQ-----EEKEAESQLVKADEMQRLRSQ 160
           AA+ +   L++ QGK     D+FK  L+   SE+     + K+ ES++ ++D+       
Sbjct: 194 AAKRKLEKLVIHQGKFKSGMDNFKTSLEPISSEELLELLKSKDHESEVGRSDQ------- 352

Query: 161 ALDAFDGADYTAAITFLDKILEVCVWDAELRELRAECFIKEGEPRKAISDLKAA 214
             +    AD  +    LD+   +  W A+  + R E    +G+ + AI  ++ A
Sbjct: 353 --EVISDADLXS---LLDRSALMATWQAQHLKGRQEMATDDGDDQGAILSIQPA 499
>10994
          Length = 2182

 Score = 29.6 bits (65), Expect = 2.9,   Method: Compositional matrix adjust.
 Identities = 16/46 (34%), Positives = 26/46 (56%)
 Frame = -3

Query: 323  VEAIRICSEVLQMEPDNVNALKDRAEAYLIEEMYDEAIQDYEAAQE 368
            +EAI+  +  L+++P +  AL  R   Y     Y +AI+D+E A E
Sbjct: 1604 LEAIQHLNLALKIDPLHTEALVARGAVYANNASYGKAIEDFEKALE 1467
>15360
          Length = 502

 Score = 28.5 bits (62), Expect = 6.1,   Method: Compositional matrix adjust.
 Identities = 9/33 (27%), Positives = 21/33 (63%)
 Frame = +1

Query: 396 YKILGVKRNAKKQEIIKAYRKLALQWHPDNFQN 428
           + +L +   + ++ +   Y++LAL+WHP+  +N
Sbjct: 61  FNLLDIPAGSDQESLKTKYKQLALKWHPEKHKN 159
>07784
          Length = 534

 Score = 28.5 bits (62), Expect = 7.2,   Method: Compositional matrix adjust.
 Identities = 18/43 (41%), Positives = 23/43 (53%), Gaps = 6/43 (13%)
 Frame = -3

Query: 196 ECFIKEGEPRKAISDLKAASKLK------SDNTEAFYKISTLY 232
            CF K  +P++AIS L   +KLK      +DN E  Y I T Y
Sbjct: 280 SCF-KPSQPQRAISRLSPRAKLKKSFYSTADNIEPQYHILTXY 155
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|30424726|ref|NP_780331.1| RAB39B, member RAS oncogene
family [Mus musculus]
         (213 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

01398                                                                 143   6e-35
34468                                                                 132   8e-32
08428                                                                 132   1e-31
33374                                                                  88   2e-25
14456                                                                 104   3e-23
05468                                                                 100   3e-22
26083                                                                  99   1e-21
07465                                                                  97   4e-21
33794                                                                  92   1e-19
17511                                                                  92   1e-19
13901                                                                  92   2e-19
07580                                                                  91   3e-19
30760                                                                  90   7e-19
33380                                                                  89   1e-18
11257                                                                  86   2e-17
32723                                                                  83   8e-17
01972                                                                  66   1e-14
00858                                                                  75   2e-14
13745                                                                  75   3e-14
19006                                                                  74   4e-14
26536                                                                  74   4e-14
12339                                                                  73   8e-14
13750                                                                  71   3e-13
11728                                                                  70   6e-13
35581                                                                  68   3e-12
19656                                                                  64   3e-11
27191                                                                  63   7e-11
34597                                                                  59   2e-09
19046                                                                  57   4e-09
01095                                                                  57   7e-09
09204                                                                  55   2e-08
34359                                                                  53   7e-08
24619                                                                  53   7e-08
31291                                                                  53   8e-08
00552                                                                  50   8e-07
09827                                                                  49   1e-06
08153                                                                  49   2e-06
14775                                                                  49   2e-06
33605                                                                  44   5e-05
18509                                                                  41   3e-04
10708                                                                  37   0.007
10862                                                                  32   0.15 
04138                                                                  31   0.31 
25796                                                                  31   0.33 
14788                                                                  29   1.1  
24352                                                                  28   2.2  
09700                                                                  28   3.7  
34156                                                                  27   4.1  
07562                                                                  27   5.2  
>01398
          Length = 1421

 Score =  143 bits (360), Expect = 6e-35,   Method: Compositional matrix adjust.
 Identities = 59/127 (46%), Positives = 92/127 (72%)
 Frame = -2

Query: 68   QERFRSITRAYYRNSVGGLLLFDITNRRSFQNVHEWLEETKVHVQPYQIVFVLVGHKCDL 127
            QERFRSITR+YYRNSVG ++++DIT R +F+N+ +W EE + H++P++ +F+++GHK D 
Sbjct: 1420 QERFRSITRSYYRNSVGVIIVYDITKRSTFENLKQWYEEARNHIEPHKAIFLVLGHKSDR 1241

Query: 128  DTQRQVTRHEAEKLAAAYGMKYIETSARDAINVEKAFTDLTRDIYELVKRGEITIQEGWE 187
            +  RQVT  E  + A  +G+K+ ETSA+   N+E  F  + +D Y+ ++ G I ++EGW+
Sbjct: 1240 EDARQVTAREGRRFAEMHGLKFFETSAKSGHNIEDVFAQIAKDTYQHLQDGHIRLEEGWD 1061

Query: 188  GVKSGFV 194
            GVK GF 
Sbjct: 1060 GVKQGFA 1040
>34468
          Length = 1502

 Score =  132 bits (333), Expect = 8e-32,   Method: Compositional matrix adjust.
 Identities = 66/149 (44%), Positives = 98/149 (65%), Gaps = 1/149 (0%)
 Frame = +1

Query: 9   FRLIVIGDSTVGKSCLIRRFTEGRFAQVSDPTVGVDFFSRLVEIEPGKRIKLQIWDTAGQ 68
           F++IVIGDS VGK+CL  RF  G+F   ++ T+GVDF  + ++++  + +KLQ+WDTAGQ
Sbjct: 496 FKIIVIGDSNVGKTCLTYRFCLGKFPDKTEATIGVDFREKSIQVD-SEHLKLQLWDTAGQ 672

Query: 69  ERFR-SITRAYYRNSVGGLLLFDITNRRSFQNVHEWLEETKVHVQPYQIVFVLVGHKCDL 127
           ERFR S+ + YYRN    + ++D+T   SF+N+  W+EE   H     I  +LVG+KCD+
Sbjct: 673 ERFRKSMVQHYYRNVHAVVFVYDMTKMSSFENMPAWIEECDRHNLTKYIPRILVGNKCDV 852

Query: 128 DTQRQVTRHEAEKLAAAYGMKYIETSARD 156
             +  V  + A+K A A+ M   ETSA+D
Sbjct: 853 VERIAVNTNLAQKFADAHNMPLFETSAKD 939
>08428
          Length = 1109

 Score =  132 bits (331), Expect = 1e-31,   Method: Compositional matrix adjust.
 Identities = 60/168 (35%), Positives = 105/168 (62%)
 Frame = -3

Query: 4    IWLYQFRLIVIGDSTVGKSCLIRRFTEGRFAQVSDPTVGVDFFSRLVEIEPGKRIKLQIW 63
            + +   ++ ++GDS VGKS ++ RF  G +    + T+G  F S+ + ++ G   + QIW
Sbjct: 1083 MQMRDVKVCLLGDSGVGKSSIVLRFVTGSYRPSQESTIGASFMSKSLVVD-GAGYRFQIW 907

Query: 64   DTAGQERFRSITRAYYRNSVGGLLLFDITNRRSFQNVHEWLEETKVHVQPYQIVFVLVGH 123
            DTAGQE+FR++   YYR +   ++++D+T  R+F++V  W++E +    P  IV  + G+
Sbjct: 906  DTAGQEKFRALAPMYYRGAAAAVIVYDVTRPRTFKSVKSWIQELR-SFGPPNIVLAIAGN 730

Query: 124  KCDLDTQRQVTRHEAEKLAAAYGMKYIETSARDAINVEKAFTDLTRDI 171
            KCDL+  R+V   +A++ A++    + ETSA  A+NVE+ FT+L R +
Sbjct: 729  KCDLEELREVVEKDAQEYASSISAIFGETSAMTAVNVEEMFTELARQL 586
>33374
          Length = 489

 Score = 88.2 bits (217), Expect(2) = 2e-25,   Method: Compositional matrix adjust.
 Identities = 41/103 (39%), Positives = 63/103 (61%)
 Frame = +1

Query: 58  IKLQIWDTAGQERFRSITRAYYRNSVGGLLLFDITNRRSFQNVHEWLEETKVHVQPYQIV 117
           +K +IWDTAGQER+ S+   YYR +   ++++DITN+ +F     W++E +    P  IV
Sbjct: 175 VKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNQDTFGRAKTWVKELQRQASP-NIV 351

Query: 118 FVLVGHKCDLDTQRQVTRHEAEKLAAAYGMKYIETSARDAINV 160
             L G+K DL  +R V   EA+  A    + ++ETSA+ A+NV
Sbjct: 352 IALAGNKADLANKRMVEFEEAQAYAEENSLLFMETSAKTAMNV 480

 Score = 43.9 bits (102), Expect(2) = 2e-25,   Method: Compositional matrix adjust.
 Identities = 17/38 (44%), Positives = 28/38 (73%)
 Frame = +2

Query: 8  QFRLIVIGDSTVGKSCLIRRFTEGRFAQVSDPTVGVDF 45
          QF+L+++G+S VGKS L+ RF +G+F +  + T+G  F
Sbjct: 29 QFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAF 142
>14456
          Length = 1867

 Score =  104 bits (260), Expect = 3e-23,   Method: Compositional matrix adjust.
 Identities = 65/171 (38%), Positives = 97/171 (56%), Gaps = 4/171 (2%)
 Frame = -1

Query: 19   VGKSCLIRRFTEGRFAQVSDPTVGVDFFSRLVEIEPGKRIKLQIWDTAGQERFRSITRAY 78
            VGKS L+ RF   +F   S  T+GV+F ++ V ++  +   +QIWDTAGQERF+S+   +
Sbjct: 1108 VGKSSLMNRFVSNKFDAQSFHTIGVEFLNKDVVVDD-ETYTMQIWDTAGQERFKSLRTPF 932

Query: 79   YRNSVGGLLLFDITNRRSFQNVHEWLEETKVHVQPYQIV---FVLVGHKCDLDTQRQVTR 135
            YR +   LL F + + +SF+N+  W +E   +      V   FV++G+K D++  RQVT 
Sbjct: 931  YRGADCCLLTFSVDSMQSFRNLSMWRKEFLYYADIQDGVTFPFVVLGNKIDVEG-RQVTN 755

Query: 136  HEAEKLAAA-YGMKYIETSARDAINVEKAFTDLTRDIYELVKRGEITIQEG 185
             EA     A     Y ETSA+DA NVEKAF    + + E+  + E+    G
Sbjct: 754  EEARSWCTANSNAPYFETSAKDATNVEKAFLAAVQRLREVEDQQEVKTAHG 602
>05468
          Length = 1558

 Score =  100 bits (250), Expect = 3e-22,   Method: Compositional matrix adjust.
 Identities = 56/170 (32%), Positives = 98/170 (57%), Gaps = 5/170 (2%)
 Frame = -3

Query: 9    FRLIVIGDSTVGKSCLIRRFTEGRFAQVSDPTVGVDFFSRLVEIEPGKRIKLQIWDTAGQ 68
            ++++VIG+   GK+ +I+R+    F+Q    T+GVDF  +++  +    I+LQ+WD AGQ
Sbjct: 1538 YKILVIGELGTGKTSIIKRYVHQFFSQHYRATIGVDFALKVLNWDADTLIRLQLWDIAGQ 1359

Query: 69   ERFRSITRAYYRNSVGGLLLFDITNRRSFQNVHEWLEETKVHVQPYQ---IVFVLVGHKC 125
            ERF ++TR YY+ +VG  ++FD+T   +F  V +W  +    VQ      +  VL+ +KC
Sbjct: 1358 ERFGNMTRVYYKEAVGAFVVFDVTRASTFDAVTKWKNDLDSKVQLADGSPVPCVLLANKC 1179

Query: 126  DLDTQRQVTR-HEAEKLAAAYG-MKYIETSARDAINVEKAFTDLTRDIYE 173
            D   +  V    + ++  +  G + + ETSA++ IN+++A   L   I E
Sbjct: 1178 DQAKEGLVNNTSQMDEFCSEKGFIGWYETSAKENINIDEAARFLVTRILE 1029
>26083
          Length = 432

 Score = 99.0 bits (245), Expect = 1e-21,   Method: Compositional matrix adjust.
 Identities = 46/119 (38%), Positives = 78/119 (65%)
 Frame = +1

Query: 6   LYQFRLIVIGDSTVGKSCLIRRFTEGRFAQVSDPTVGVDFFSRLVEIEPGKRIKLQIWDT 65
           L +F+L+ +G+ +VGK+ LI RF    F      T+G+DF S+ + +E  + I+LQ+WDT
Sbjct: 70  LRKFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLED-RTIRLQLWDT 246

Query: 66  AGQERFRSITRAYYRNSVGGLLLFDITNRRSFQNVHEWLEETKVHVQPYQIVFVLVGHK 124
           AGQERFRS+  +Y R+S   ++++DITN  SF    +W+++ +   +   ++ +LVG+K
Sbjct: 247 AGQERFRSLIPSYIRDSSVAVVVYDITNANSFHQTSKWIDDVRTE-RGSDVIIMLVGNK 420
>07465
          Length = 1103

 Score = 97.4 bits (241), Expect = 4e-21,   Method: Compositional matrix adjust.
 Identities = 53/143 (37%), Positives = 85/143 (59%)
 Frame = +3

Query: 22  SCLIRRFTEGRFAQVSDPTVGVDFFSRLVEIEPGKRIKLQIWDTAGQERFRSITRAYYRN 81
           S +I+R+ +G F +    T+GVDF  R +E+  G+ ++L +WDTAGQE F +IT+AYYR 
Sbjct: 240 SSMIQRYCKGIFTKDYKKTIGVDFLERQIEV-GGEDVRLMLWDTAGQEEFDAITKAYYRG 416

Query: 82  SVGGLLLFDITNRRSFQNVHEWLEETKVHVQPYQIVFVLVGHKCDLDTQRQVTRHEAEKL 141
           +   +L F   +R SF+ +  W  + KV  +  +I  V+V +K DL     V   EAE L
Sbjct: 417 AQACVLAFSTVDRDSFEALETW--KRKVEDEVGEIGMVIVQNKIDLIDDAVVRPEEAENL 590

Query: 142 AAAYGMKYIETSARDAINVEKAF 164
           A    +++  TS ++ +NV++ F
Sbjct: 591 AKKLRLRFYRTSVKENMNVDEVF 659
>33794
          Length = 779

 Score = 92.4 bits (228), Expect = 1e-19,   Method: Compositional matrix adjust.
 Identities = 56/145 (38%), Positives = 82/145 (56%), Gaps = 4/145 (2%)
 Frame = -1

Query: 29  TEGRFAQVSDPTV----GVDFFSRLVEIEPGKRIKLQIWDTAGQERFRSITRAYYRNSVG 84
           TE  F   +D T      V + +  + +E GKR+KLQIWDT+GQ RF +I R+Y R + G
Sbjct: 746 TENPFCSGNDCTSHILQTVAYKTTTILLE-GKRVKLQIWDTSGQGRFCTIIRSYSRGAQG 570

Query: 85  GLLLFDITNRRSFQNVHEWLEETKVHVQPYQIVFVLVGHKCDLDTQRQVTRHEAEKLAAA 144
            +L++DITN+ SF  +  WL+E + H     I  VLVG++  L  +RQV   +AE  A+ 
Sbjct: 569 IILVYDITNKWSFDGIDRWLKEVEEHAP--GIPKVLVGNRLHLAYKRQVAAKQAETYASR 396

Query: 145 YGMKYIETSARDAINVEKAFTDLTR 169
             M   E S     N+ ++F +L R
Sbjct: 395 NNMSCFEISPLCDFNIRESFCELAR 321
>17511
          Length = 483

 Score = 92.4 bits (228), Expect = 1e-19,   Method: Compositional matrix adjust.
 Identities = 43/122 (35%), Positives = 77/122 (63%), Gaps = 3/122 (2%)
 Frame = -3

Query: 9   FRLIVIGDSTVGKSCLIRRFTEGRFAQVSDPTVGVDFFSRLVEIEPGKRIKLQIWDTAGQ 68
            ++I++GDS VGK+ L+ ++   +F+     T+G DF ++ V ++  + + +QIWDTAGQ
Sbjct: 364 LKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVD-DRLVTMQIWDTAGQ 188

Query: 69  ERFRSITRAYYRNSVGGLLLFDITNRRSFQNVHEWLEETKVHVQPY---QIVFVLVGHKC 125
           ERF+S+  A+YR +   +L+FD+T   +F+++  W +E  +   P       FV++G+K 
Sbjct: 187 ERFQSLGVAFYRGADCCVLVFDVTMPNTFRSLDSWRDEFLIQASPRDPENFPFVVIGNKI 8

Query: 126 DL 127
           DL
Sbjct: 7   DL 2
>13901
          Length = 962

 Score = 92.0 bits (227), Expect = 2e-19,   Method: Compositional matrix adjust.
 Identities = 39/95 (41%), Positives = 63/95 (66%)
 Frame = -3

Query: 9   FRLIVIGDSTVGKSCLIRRFTEGRFAQVSDPTVGVDFFSRLVEIEPGKRIKLQIWDTAGQ 68
           F++I+IGD TVGK+  ++R+    F +    T+GVDF  +++       IKLQ+WD AGQ
Sbjct: 285 FKVIIIGDPTVGKTSFVQRYVNDSFRRDYKMTIGVDFALKVIRWSDKCNIKLQLWDIAGQ 106

Query: 69  ERFRSITRAYYRNSVGGLLLFDITNRRSFQNVHEW 103
           ERF S+TR YY+++   +++FD+T + ++QN   W
Sbjct: 105 ERFTSMTRVYYKDAHACIVMFDLTQKNTYQNAIRW 1
>07580
          Length = 921

 Score = 90.9 bits (224), Expect = 3e-19,   Method: Compositional matrix adjust.
 Identities = 50/144 (34%), Positives = 84/144 (58%)
 Frame = +3

Query: 28  FTEGRFAQVSDPTVGVDFFSRLVEIEPGKRIKLQIWDTAGQERFRSITRAYYRNSVGGLL 87
             +G F +  DPT+  D + + VE++ G++  L+I DTAG E+F ++   Y +N  G LL
Sbjct: 120 LCKGIFVEKYDPTIE-DSYRKQVEVD-GQQCMLEILDTAGTEQFTAMRDLYMKNGQGFLL 293

Query: 88  LFDITNRRSFQNVHEWLEETKVHVQPYQIVFVLVGHKCDLDTQRQVTRHEAEKLAAAYGM 147
            + IT + +F ++ E  E+         +  +LVG+KCDL+ +R V + + + LA ++  
Sbjct: 294 AYSITAQSTFNDLQELREQILRVKDTDDVPMLLVGNKCDLEDERVVGKDQGQGLARSFSC 473

Query: 148 KYIETSARDAINVEKAFTDLTRDI 171
            ++ETSA+  INV + F DL R I
Sbjct: 474 AFLETSAKARINVNEIFMDLVRQI 545
>30760
          Length = 596

 Score = 90.1 bits (222), Expect = 7e-19,   Method: Compositional matrix adjust.
 Identities = 53/168 (31%), Positives = 90/168 (53%), Gaps = 3/168 (1%)
 Frame = -1

Query: 10  RLIVIGDSTVGKSCLIRRF--TEGRFAQVSDPTVGVDFFSRLVEIEPGK-RIKLQIWDTA 66
           + IV GDS VGKS + + F      F +    T GV+   +LV I   + +++L ++D+A
Sbjct: 524 KCIVTGDSGVGKSSICQVFHSDSAHFPKNYSMTTGVEVLVKLVNIPDSRDQVELYLFDSA 345

Query: 67  GQERFRSITRAYYRNSVGGLLLFDITNRRSFQNVHEWLEETKVHVQPYQIVFVLVGHKCD 126
           G+E F      ++      ++++D+T+  SF     WLE  +       I  VLV +K D
Sbjct: 344 GKEIFSENVTKFWDQPSVVMVVYDVTDETSFSGCVRWLERVRAAKPNTVIPGVLVANKTD 165

Query: 127 LDTQRQVTRHEAEKLAAAYGMKYIETSARDAINVEKAFTDLTRDIYEL 174
           LD +R+V+R E + LA ++G++Y E SA++  N +  F  L    ++L
Sbjct: 164 LDERRRVSRKEGKDLAQSHGLEYFECSAKEMQNTDTPFFCLAHAFHKL 21
>33380
          Length = 282

 Score = 89.4 bits (220), Expect = 1e-18,   Method: Compositional matrix adjust.
 Identities = 41/76 (53%), Positives = 56/76 (73%)
 Frame = +3

Query: 56  KRIKLQIWDTAGQERFRSITRAYYRNSVGGLLLFDITNRRSFQNVHEWLEETKVHVQPYQ 115
           KR+KLQIWDTAGQER+R+IT AYYR ++G +L++D+TN  SF  V +W  + K +     
Sbjct: 54  KRVKLQIWDTAGQERYRTITTAYYRGAMGFILMYDVTNEESFNAVQDWCTQIKTYSWDNA 233

Query: 116 IVFVLVGHKCDLDTQR 131
            V VLVG+KCDL+ +R
Sbjct: 234 QV-VLVGNKCDLEDER 278
>11257
          Length = 1102

 Score = 85.5 bits (210), Expect = 2e-17,   Method: Compositional matrix adjust.
 Identities = 44/124 (35%), Positives = 77/124 (62%), Gaps = 4/124 (3%)
 Frame = -2

Query: 55   GKRIKLQIWDTAGQERFRSITRAYYRNSVGGLLLFDITNRRSFQNVHEWLEE--TKVHVQ 112
            G+   +QIWDTAGQER++S+   +YR +   LL F + N +S Q++ +W +E      +Q
Sbjct: 1035 GETFTMQIWDTAGQERYKSLRTPFYRGTDCCLLTFSVDNLKSLQSLSDWYDEFVNYADIQ 856

Query: 113  -PYQIVFVLVGHKCDLDTQRQVTRHEAEKLAAAYG-MKYIETSARDAINVEKAFTDLTRD 170
                  FV++G+K D++ +R+V+  +A      +G + Y ETSA+D++NV++AF  + R 
Sbjct: 855  DSASFPFVIIGNKADIE-EREVSSEDAYNWCRTHGNLPYFETSAKDSLNVQQAFLAVVRR 679

Query: 171  IYEL 174
            + E+
Sbjct: 678  LREM 667
>32723
          Length = 384

 Score = 82.8 bits (203), Expect = 8e-17,   Method: Compositional matrix adjust.
 Identities = 40/115 (34%), Positives = 78/115 (67%)
 Frame = +2

Query: 68  QERFRSITRAYYRNSVGGLLLFDITNRRSFQNVHEWLEETKVHVQPYQIVFVLVGHKCDL 127
           QERFRSIT++YYR++   +L++D+ +++S++++ +W+ E +++     + F LVG+K D 
Sbjct: 2   QERFRSITQSYYRSANALILVYDVCSQQSYESLPQWIHEIELYAGTKVLAF-LVGNKIDQ 178

Query: 128 DTQRQVTRHEAEKLAAAYGMKYIETSARDAINVEKAFTDLTRDIYELVKRGEITI 182
             +R++  H  ++ A  Y M+++ETSA++A NVEK F+ +    Y+L  + + T+
Sbjct: 179 TDKREIPTHIGKEFAERYEMRFLETSAKEADNVEKLFSTIA---YQLTAQAQGTL 334
>01972
          Length = 2359

 Score = 66.2 bits (160), Expect(2) = 1e-14,   Method: Compositional matrix adjust.
 Identities = 40/132 (30%), Positives = 67/132 (50%)
 Frame = +3

Query: 40  TVGVDFFSRLVEIEPGKRIKLQIWDTAGQERFRSITRAYYRNSVGGLLLFDITNRRSFQN 99
           T+GV+    L     GK +K  +WDTAGQE+F  +   YY      +++FD+T+R +++N
Sbjct: 396 TLGVEVHPLLFHTSRGK-LKFNVWDTAGQEKFGGLRDGYYIQGQCAVIMFDVTSRVTYKN 572

Query: 100 VHEWLEETKVHVQPYQIVFVLVGHKCDLDTQRQVTRHEAEKLAAAYGMKYIETSARDAIN 159
           V  W  +     +   I  VL G+K D+  ++   + +A        ++Y + SA+   N
Sbjct: 573 VPNWHRDLVRVCE--NIPIVLCGNKVDIKDRK--VKAKAIVFHRKKNLQYYDISAKSNYN 740

Query: 160 VEKAFTDLTRDI 171
            EK F  L R +
Sbjct: 741 FEKPFLWLARKL 776

 Score = 30.0 bits (66), Expect(2) = 1e-14,   Method: Compositional matrix adjust.
 Identities = 11/31 (35%), Positives = 19/31 (61%)
 Frame = +1

Query: 9   FRLIVIGDSTVGKSCLIRRFTEGRFAQVSDP 39
           F+L+++GD  VGK+  ++R   G F +   P
Sbjct: 304 FKLVLVGDGGVGKTTFVKRHVTGEFEKNMLP 396
>00858
          Length = 1658

 Score = 74.7 bits (182), Expect = 2e-14,   Method: Compositional matrix adjust.
 Identities = 55/166 (33%), Positives = 91/166 (54%)
 Frame = -2

Query: 6    LYQFRLIVIGDSTVGKSCLIRRFTEGRFAQVSDPTVGVDFFSRLVEIEPGKRIKLQIWDT 65
            + +++L+V+G   VGKS L  +  +  F +  DPT   D   + V I+ G+   L I DT
Sbjct: 1597 MTEYKLVVVGAGGVGKSALTIQLXQNHFVEEYDPTXE-DSXRKQVVID-GETCLLDILDT 1424

Query: 66   AGQERFRSITRAYYRNSVGGLLLFDITNRRSFQNVHEWLEETKVHVQPYQIVFVLVGHKC 125
            AGQE   ++     R   G L +F + N +SF++++++ E+ K      ++  VLVG+K 
Sbjct: 1423 AGQEEXSAMRDQCMRTGEGFLCVFAVXNLKSFEDINQYREQIKRVKDADEVPMVLVGNKV 1244

Query: 126  DLDTQRQVTRHEAEKLAAAYGMKYIETSARDAINVEKAFTDLTRDI 171
            DL   R V + + + +A  Y + Y+ETSA+    V+ AF  L R+I
Sbjct: 1243 DLPI-RNVEQRQGKHMAELYHIPYVETSAKTRQGVDDAFYTLVREI 1109
>13745
          Length = 1045

 Score = 74.7 bits (182), Expect = 3e-14,   Method: Compositional matrix adjust.
 Identities = 39/116 (33%), Positives = 65/116 (56%), Gaps = 3/116 (2%)
 Frame = +2

Query: 68  QERFRSITRAYYRNSVGGLLLFDITNRRSFQNVHEWLEETKVHV---QPYQIVFVLVGHK 124
           QERF+S+  A+YR +   +L++D+T   SF+N+  W +E  +      P    FV++G+K
Sbjct: 2   QERFQSLGVAFYRGADCCVLVYDVTAPNSFKNLDSWRDEFLIQASPRDPEHFPFVVLGNK 181

Query: 125 CDLDTQRQVTRHEAEKLAAAYGMKYIETSARDAINVEKAFTDLTRDIYELVKRGEI 180
            DLD ++  TR   +   +   + Y ETSA++ INVE AF  + ++  E     E+
Sbjct: 182 VDLDNRQVSTRRAQQWCQSKNDIPYYETSAKEGINVEMAFQTIAKNALEQETEAEL 349
>19006
          Length = 568

 Score = 73.9 bits (180), Expect = 4e-14,   Method: Compositional matrix adjust.
 Identities = 43/140 (30%), Positives = 84/140 (60%), Gaps = 5/140 (3%)
 Frame = -2

Query: 7   YQFRLIVIGDSTVGKSCLIRRFTEGRFAQVSDPTVGVDFFSRLVEIEPGKRIKLQIWDTA 66
           ++ +L+++GD   GK+CL+  F++ +F +V  PTV  ++ +  +E++  K+++L +WDTA
Sbjct: 441 HKEKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVAD-IEVD-SKQVELALWDTA 268

Query: 67  GQERFRSITRAYYRNSVGGLLLFDITNRRSFQNVHE-WLEETKVHVQPYQIVFVLVGHKC 125
           GQE +  +    Y ++   L+ F I +  S +N+ E W  E + H  P  +  +LVG+K 
Sbjct: 267 GQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVR-HFCP-NVPIILVGNKK 94

Query: 126 DL----DTQRQVTRHEAEKL 141
           DL    +T+R++ + + E +
Sbjct: 93  DLRNDENTKRELMKMKQEPV 34
>26536
          Length = 829

 Score = 73.9 bits (180), Expect = 4e-14,   Method: Compositional matrix adjust.
 Identities = 45/123 (36%), Positives = 65/123 (52%), Gaps = 7/123 (5%)
 Frame = +2

Query: 56  KRIKLQIWDTAGQERFRSITRAYYRNSVGGLLLFDITNRRSFQN---VHEWL----EETK 108
           +R+     DTAGQE + S+   Y R+  G ++++ +T+  SFQ    V  WL    +ET 
Sbjct: 122 RRVSWTFLDTAGQEEYSSMREHYTRSGDGFIVVYSVTDVTSFQEAEAVFRWLTRFQDETS 301

Query: 109 VHVQPYQIVFVLVGHKCDLDTQRQVTRHEAEKLAAAYGMKYIETSARDAINVEKAFTDLT 168
           +H        VL G+K DL + R+VT  E  K+A   GM Y ETSA+   NV + +  L 
Sbjct: 302 IHA-------VLCGNKTDLTSDRKVTPEEGRKMADRLGMLYFETSAKTGDNVSQVYHGLL 460

Query: 169 RDI 171
           R I
Sbjct: 461 RSI 469

 Score = 36.2 bits (82), Expect = 0.009,   Method: Compositional matrix adjust.
 Identities = 15/44 (34%), Positives = 29/44 (65%)
 Frame = +2

Query: 9   FRLIVIGDSTVGKSCLIRRFTEGRFAQVSDPTVGVDFFSRLVEI 52
           ++++++G   VGKS L  RFT+  F  V DPT+  D + +++++
Sbjct: 488 YKIVMLGSGGVGKSSLTIRFTQDTFLDVYDPTI-EDSYRKMIQV 616
>12339
          Length = 578

 Score = 73.2 bits (178), Expect = 8e-14,   Method: Compositional matrix adjust.
 Identities = 43/149 (28%), Positives = 75/149 (50%), Gaps = 3/149 (2%)
 Frame = -2

Query: 68  QERFRSITRAYYRNSVGGLLLFDITNRRSFQNVHEWLEETKVHVQPY---QIVFVLVGHK 124
           QERF+S+  A+YR +   +L++D+T  ++F ++  W  E      P       FV++G+K
Sbjct: 577 QERFQSLGVAFYRGADCCILVYDVTEXKTFDSLDSWQREFLNQASPRDPEHFPFVVIGNK 398

Query: 125 CDLDTQRQVTRHEAEKLAAAYGMKYIETSARDAINVEKAFTDLTRDIYELVKRGEITIQE 184
            DLD +    +      +   G+ Y ETSA++AINVE+AF  + ++   L +  E+ I +
Sbjct: 397 IDLDNRVVTAKRGQGWCSTKGGIPYFETSAKEAINVEQAFQTVAKNA--LAQESEVEIDD 224

Query: 185 GWEGVKSGFVPNVVHSSEEVIKSERRCLC 213
                     P+ +  S +  +   RC C
Sbjct: 223 ---------FPSEIRLSNDDSRPRERCAC 164
>13750
          Length = 503

 Score = 71.2 bits (173), Expect = 3e-13,   Method: Compositional matrix adjust.
 Identities = 43/149 (28%), Positives = 75/149 (50%), Gaps = 2/149 (1%)
 Frame = -2

Query: 21  KSCLIRRFTEGRFAQVSDPTVGVDFFSRLVEIEPGK-RIKLQIWDTAGQERFRSITRAYY 79
           K+CL+RR+ +G F   + PT+ V   S   E       ++  +WDT G E +RS+  +++
Sbjct: 502 KTCLLRRYQKGFFMDRTMPTIAV-LCSEFNESRTDPLNVRYTLWDTGGAETYRSLWVSHF 326

Query: 80  RNSVGGLLLFDITNRRSFQNVHE-WLEETKVHVQPYQIVFVLVGHKCDLDTQRQVTRHEA 138
           R +   LL++D+T   SF      W +    ++   Q++F  VG K DL+  R ++    
Sbjct: 325 RGAQVALLVYDVTCEWSFLTATTVWRKALMKNIPEAQVIF--VGSKTDLEENRVISTERG 152

Query: 139 EKLAAAYGMKYIETSARDAINVEKAFTDL 167
           +  A   G  + ETS+    NV+  F ++
Sbjct: 151 QAFATQCGYTFFETSSVTGKNVDAVFWEI 65
>11728
          Length = 635

 Score = 70.1 bits (170), Expect = 6e-13,   Method: Compositional matrix adjust.
 Identities = 56/168 (33%), Positives = 80/168 (47%), Gaps = 14/168 (8%)
 Frame = -1

Query: 1   MEAIWLYQFRLIVIGDSTVGKSCLIRRFTEGRFAQVSDPTVGVDFFSRLVEIEPGKRIKL 60
           M+AI     + +V+GD  VGK+CL+  +T   F     PTV  D +S  V ++  K I L
Sbjct: 497 MQAI-----KCVVVGDGAVGKTCLLISYTTNAFPGEYIPTV-FDNYSANVMVD-SKPINL 339

Query: 61  QIWDTAGQERFRSITRAYYRNSVGGLLLFDITNRRSFQNVH-EWLEETKVHVQPYQIVFV 119
            +WDTAGQE +  +    Y  +   L+ F + +  SF+NV  +W  E   H     I  +
Sbjct: 338 GLWDTAGQEDYDRLRPLSYPQTDVFLICFSLISPASFENVKAKWYPEVSHHCPNTPI--I 165

Query: 120 LVGHKCDLDTQRQVTRHEAEK----------LAAAYGM---KYIETSA 154
           LVG K DL   ++      EK          LA A  +   KY+E SA
Sbjct: 164 LVGTKLDLREDKETIEKLKEKKLAPITYPQGLAMAKDIGAGKYLECSA 21
>35581
          Length = 364

 Score = 68.2 bits (165), Expect = 3e-12,   Method: Compositional matrix adjust.
 Identities = 32/106 (30%), Positives = 57/106 (53%), Gaps = 2/106 (1%)
 Frame = +2

Query: 9   FRLIVIGDSTVGKSCLIRRFTEGRFAQVSDPTVGVDFFSRLVEIEPGKRIKLQIWDTAGQ 68
           F+ +++GD+ VGK+CL+ R    +F      ++        V +  G    + +WDTAGQ
Sbjct: 47  FKCVLLGDAGVGKTCLLNRLATDKFLDSPLTSLTTASLLTTVTLTSGVMASVDLWDTAGQ 226

Query: 69  ERFRSITRAYYRNSVGGLLLFDITNRRSFQNVHEWLEETKV--HVQ 112
           ER+RS+T +YYR++   L+++D  ++       +W +   V  H Q
Sbjct: 227 ERYRSLTSSYYRDTKAVLIVYDAEHKLKLT---DWTDRAAVPHHTQ 355
>19656
          Length = 428

 Score = 64.3 bits (155), Expect = 3e-11,   Method: Compositional matrix adjust.
 Identities = 38/113 (33%), Positives = 59/113 (52%), Gaps = 1/113 (0%)
 Frame = +3

Query: 1   MEAIWLYQFRLIVIGDSTVGKSCLIRRFTEGRFAQVSDPTVGVDFFSRLVEIEPGKRIKL 60
           M+AI     + +V+GD  VGK+CL+  +T   F     PTV  D +S  V ++ G+ + L
Sbjct: 105 MQAI-----KCVVVGDGAVGKTCLLISYTTNAFPGEYIPTV-FDNYSANVMVD-GRPVNL 263

Query: 61  QIWDTAGQERFRSITRAYYRNSVGGLLLFDITNRRSFQNVH-EWLEETKVHVQ 112
            +WDTAGQE +  +    Y  +   LL F + +  SF+N+  +W  E   H  
Sbjct: 264 GLWDTAGQEDYDRLRPLSYPQTDVFLLCFSVASPASFENIRAKWYPEVNHHCP 422
>27191
          Length = 443

 Score = 63.2 bits (152), Expect = 7e-11,   Method: Compositional matrix adjust.
 Identities = 28/86 (32%), Positives = 48/86 (55%)
 Frame = +1

Query: 21  KSCLIRRFTEGRFAQVSDPTVGVDFFSRLVEIEPGKRIKLQIWDTAGQERFRSITRAYYR 80
           K+CLI+ F E +F Q   PTVGVD+  ++  +  G  +++ +WD +G   +  +    Y 
Sbjct: 1   KTCLIKHFCESKFNQGYQPTVGVDYGFKIQTVN-GVDMRVHMWDLSGSNEYLDVRNELYT 177

Query: 81  NSVGGLLLFDITNRRSFQNVHEWLEE 106
            S    ++FD++N  SF+ +  WL E
Sbjct: 178 GSDAIFIVFDVSNTPSFEALDSWLRE 255
>34597
          Length = 773

 Score = 58.5 bits (140), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 25/80 (31%), Positives = 50/80 (62%)
 Frame = -2

Query: 94  RRSFQNVHEWLEETKVHVQPYQIVFVLVGHKCDLDTQRQVTRHEAEKLAAAYGMKYIETS 153
           ++SF+N+ +WL     H     +  +++G+KCD+  +R V++   E +A  + ++++ETS
Sbjct: 715 KKSFENIVKWLRNIDEHANE-DVEKMILGNKCDMTDKRVVSKERGEAIAREHSIRFMETS 539

Query: 154 ARDAINVEKAFTDLTRDIYE 173
           A+  IN+E+AF +L   I +
Sbjct: 538 AKSNINIERAFCELAEAILD 479
>19046
          Length = 445

 Score = 57.4 bits (137), Expect = 4e-09,   Method: Compositional matrix adjust.
 Identities = 38/111 (34%), Positives = 58/111 (52%), Gaps = 7/111 (6%)
 Frame = -2

Query: 68  QERFRSITRAYYRNSVGGLLLFDITNRRSFQNVHEWLEETKVHVQPYQI------VFVLV 121
           QE F ++   Y R   G LL+F +T+ RSF+N+  +      H Q  ++        +L 
Sbjct: 444 QEEFSAMREQYMRKGDGFLLVFSVTDFRSFENMANF------HTQILRVKDRDSYPMILC 283

Query: 122 GHKCDLDTQRQVTRHEAEKLAAAYGMKYIETSARD-AINVEKAFTDLTRDI 171
            +K DL  QR+V+  +   LA    + YIETSA+D  +NV+ AF  + R I
Sbjct: 282 ANKVDLVHQRKVSEEQVRDLATRLRIPYIETSAKDPPLNVDLAFHQVVRVI 130
>01095
          Length = 1745

 Score = 56.6 bits (135), Expect = 7e-09,   Method: Compositional matrix adjust.
 Identities = 28/85 (32%), Positives = 47/85 (55%)
 Frame = -1

Query: 87   LLFDITNRRSFQNVHEWLEETKVHVQPYQIVFVLVGHKCDLDTQRQVTRHEAEKLAAAYG 146
            +++DITN+ +F     W++E +    P  IV  L G+K DL  +R V   EA+  A    
Sbjct: 1745 VVYDITNQDTFGRAKTWVKELQRQASP-NIVIALAGNKADLANKRMVEFEEAQAYAEENS 1569

Query: 147  MKYIETSARDAINVEKAFTDLTRDI 171
            + ++ETSA+ A+NV   F  + + +
Sbjct: 1568 LLFMETSAKTAMNVNDIFLAIAKKL 1494
>09204
          Length = 1051

 Score = 55.5 bits (132), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 33/105 (31%), Positives = 55/105 (52%), Gaps = 4/105 (3%)
 Frame = -3

Query: 70   RFRSITRAYYRNSVGGLLLFDITNRRSFQNVHEWLEETKVHVQPYQIVFVLVGHKCDL-- 127
            R+ +++R YYR +   +L FD+T++ SF  +  W+ E + H +  ++   + G K DL  
Sbjct: 1049 RYEAMSRIYYRGAKAAILCFDLTDKSSFDRIRFWIGELRQHEEECKL--YICGTKFDLVH 876

Query: 128  --DTQRQVTRHEAEKLAAAYGMKYIETSARDAINVEKAFTDLTRD 170
                +R V R  A+ LA     +  ETS+    N+EK FT +  D
Sbjct: 875  DDPERRAVPRSVAKALADDCMAEIYETSSMTGDNIEKLFTKIAED 741
>34359
          Length = 1042

 Score = 53.1 bits (126), Expect = 7e-08,   Method: Compositional matrix adjust.
 Identities = 32/124 (25%), Positives = 62/124 (50%)
 Frame = +3

Query: 8   QFRLIVIGDSTVGKSCLIRRFTEGRFAQVSDPTVGVDFFSRLVEIEPGKRIKLQIWDTAG 67
            F+L+++G      + +++R   G   +    T+GV+          G  ++  +WDTAG
Sbjct: 51  NFKLVLVGGRWEWANNIVKRHVTGS*KKYVA-TLGVEVHPLQFNTSRGL-LRFNVWDTAG 224

Query: 68  QERFRSITRAYYRNSVGGLLLFDITNRRSFQNVHEWLEETKVHVQPYQIVFVLVGHKCDL 127
           QE+F  +   YY      +++FD+T+R +++NV  W  +     +   I  VL G+K D+
Sbjct: 225 QEKFGGLRDGYYIQGTCAIIMFDVTSRVTYKNVPNWHRDLVRVCE--NIPIVLCGNKVDI 398

Query: 128 DTQR 131
             ++
Sbjct: 399 KDRK 410
>24619
          Length = 509

 Score = 53.1 bits (126), Expect = 7e-08,   Method: Compositional matrix adjust.
 Identities = 36/111 (32%), Positives = 56/111 (50%), Gaps = 7/111 (6%)
 Frame = -2

Query: 68  QERFRSITRAYYRNSVGGLLLFDITNRRSFQNVHEWLEETKVHVQPYQI------VFVLV 121
           QE F ++   Y R   G LL+F + + +SF+N+         H Q  ++        +L 
Sbjct: 508 QEEFSAMREQYMRKGDGFLLVFSVIDYQSFENM------VNFHTQILRVKDRDTYPMILC 347

Query: 122 GHKCDLDTQRQVTRHEAEKLAAAYGMKYIETSARD-AINVEKAFTDLTRDI 171
            +K DL  QR+V+  +   LA    + YIETSA+D  +NV+ AF  + R I
Sbjct: 346 ANKVDLVHQRKVSEEQVRDLATRLRIPYIETSAKDPPLNVDLAFHQVVRVI 194
>31291
          Length = 446

 Score = 53.1 bits (126), Expect = 8e-08,   Method: Compositional matrix adjust.
 Identities = 40/124 (32%), Positives = 60/124 (48%), Gaps = 14/124 (11%)
 Frame = -1

Query: 60  LQIWDTAGQERFRSITRAYYRNSVGGLLLFDITNRRSFQNVH-EWLEETKVHVQPYQIVF 118
           LQ+WDTAGQE +  +    Y N+   +L F + +  S +NV  +W  E + H  P+ +  
Sbjct: 446 LQLWDTAGQEDYDRLRPLAYPNTDVFMLXFSLMSEASMKNVKVKWYPEIR-HHDPH-VPI 273

Query: 119 VLVGHKCDL------------DTQRQVTRHEAEKLAAAYGMK-YIETSARDAINVEKAFT 165
           VLVG K DL              Q  V+ ++   LA A   K Y E S++   N++ AF 
Sbjct: 272 VLVGTKLDLRQDKEAVRKLRSSRQDPVSSNQGNDLAKAIKAKRYFECSSKTQENLKTAFE 93

Query: 166 DLTR 169
           +  R
Sbjct: 92  ETVR 81
>00552
          Length = 455

 Score = 49.7 bits (117), Expect = 8e-07,   Method: Compositional matrix adjust.
 Identities = 20/45 (44%), Positives = 31/45 (68%)
 Frame = -3

Query: 62  IWDTAGQERFRSITRAYYRNSVGGLLLFDITNRRSFQNVHEWLEE 106
           IWDTAGQER++S+   +YR +   LL F + N +S Q++ +W +E
Sbjct: 147 IWDTAGQERYKSLRTPFYRGTDCCLLTFSVDNLKSLQSLSDWYDE 13

 Score = 37.7 bits (86), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 16/45 (35%), Positives = 29/45 (64%)
 Frame = -1

Query: 9   FRLIVIGDSTVGKSCLIRRFTEGRFAQVSDPTVGVDFFSRLVEIE 53
            +++++GD  VGKS L+ RF   +F   S  T+GV+F ++ V ++
Sbjct: 443 LKVVLLGDGGVGKSSLMNRFVSNKFDAQSFHTIGVEFLTKDVVVD 309
>09827
          Length = 1201

 Score = 48.9 bits (115), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 29/119 (24%), Positives = 55/119 (46%)
 Frame = -3

Query: 9    FRLIVIGDSTVGKSCLIRRFTEGRFAQVSDPTVGVDFFSRLVEIEPGKRIKLQIWDTAGQ 68
             R++++G    GK+ ++ +   G     + PT+G +     VE    K I   +WD  GQ
Sbjct: 1112 MRILMVGLDAAGKTTILYKLKLGEIV-TTIPTIGFN-----VETVEYKNISFTVWDVGGQ 951

Query: 69   ERFRSITRAYYRNSVGGLLLFDITNRRSFQNVHEWLEETKVHVQPYQIVFVLVGHKCDL 127
            ++ R + R Y++N+ G + + D  ++   Q   E L       +    V ++  +K DL
Sbjct: 950  DKIRPLWRHYFQNTQGLIFVVDSNDKERVQEAREELTRMLNEDELRDAVLLVFANKQDL 774
>08153
          Length = 1703

 Score = 48.5 bits (114), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 31/132 (23%), Positives = 59/132 (44%), Gaps = 3/132 (2%)
 Frame = +1

Query: 8   QFRLIVIGDSTVGKSCLIRRFTEGRFAQVSDPTVGVDFFSRLVEIEPGKRIKLQIWDTAG 67
           + R++++G    GK+ ++ +   G     + PT+G +     VE    K I   +WD  G
Sbjct: 82  EVRILMVGLDAAGKTTILYKLKLGEIV-TTIPTIGFN-----VETVEYKNISFTVWDVGG 243

Query: 68  QERFRSITRAYYRNSVGGLLLFDITNRRSFQNVHEWLEETKVHVQPYQIVFVLVGHKCDL 127
           Q++ R + R Y++N+ G + + D  +R       E L            + ++  +K DL
Sbjct: 244 QDKIRPLWRHYFQNTQGLIFVVDSNDRERINEAKEELARMLNEDDLRDAIILVFANKQDL 423

Query: 128 D---TQRQVTRH 136
               +  +VT H
Sbjct: 424 PNAYSASEVTAH 459
>14775
          Length = 380

 Score = 48.5 bits (114), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 25/76 (32%), Positives = 43/76 (56%), Gaps = 1/76 (1%)
 Frame = -2

Query: 21  KSCLIRRFTEGRFAQVSDPTVGVDFFSRLVEIEPGK-RIKLQIWDTAGQERFRSITRAYY 79
           K+CL+RR+ +G F   + PT+ V   S   E       ++  +WDT G E +RS+  +++
Sbjct: 379 KTCLLRRYQKGFFMDRTMPTIAV-LCSEFNESRTDPLNVRYTLWDTGGAETYRSLWVSHF 203

Query: 80  RNSVGGLLLFDITNRR 95
           R +   LL++D+T  R
Sbjct: 202 RGAQVALLVYDVTCER 155
>33605
          Length = 888

 Score = 43.9 bits (102), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 23/87 (26%), Positives = 46/87 (52%)
 Frame = +1

Query: 8   QFRLIVIGDSTVGKSCLIRRFTEGRFAQVSDPTVGVDFFSRLVEIEPGKRIKLQIWDTAG 67
           + RL+++G    GK+ ++++F       +S PT+G +     ++    +  KL +WD  G
Sbjct: 496 EVRLLMLGLDNAGKTTILKKFNGEDIDTIS-PTLGFN-----IKTLEHRGFKLNVWDVGG 657

Query: 68  QERFRSITRAYYRNSVGGLLLFDITNR 94
           Q+  RS  R Y+ ++ G + + D  +R
Sbjct: 658 QQSLRSYWRNYFESTDGLVWVVDSADR 738
>18509
          Length = 625

 Score = 41.2 bits (95), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 22/57 (38%), Positives = 34/57 (59%)
 Frame = -3

Query: 115 QIVFVLVGHKCDLDTQRQVTRHEAEKLAAAYGMKYIETSARDAINVEKAFTDLTRDI 171
           ++  VLVG+K DL   R V + + + +A  Y + Y+ETSA+    V+ AF  L R+I
Sbjct: 530 EVPMVLVGNKVDLPI-RNVEQRQGKHMAELYHIPYVETSAKTRQGVDDAFYTLVREI 363
>10708
          Length = 2775

 Score = 36.6 bits (83), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 15/47 (31%), Positives = 28/47 (59%)
 Frame = -2

Query: 56   KRIKLQIWDTAGQERFRSITRAYYRNSVGGLLLFDITNRRSFQNVHE 102
            ++++L +WDTAGQE +  +    Y ++   L+ F I +  S +N+ E
Sbjct: 2729 QQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPE 2589
>10862
          Length = 2896

 Score = 32.3 bits (72), Expect = 0.15,   Method: Compositional matrix adjust.
 Identities = 15/69 (21%), Positives = 30/69 (43%)
 Frame = -3

Query: 59   KLQIWDTAGQERFRSITRAYYRNSVGGLLLFDITNRRSFQNVHEWLEETKVHVQPYQIVF 118
            +  +WD  GQ++ R + R YY  + G + + D  +R       + L       +    + 
Sbjct: 2483 QFNVWDVGGQDKIRPLWRHYYTGTQGLIFVVDCADRDRIDEARQELHRIINDREMRDAII 2304

Query: 119  VLVGHKCDL 127
            ++  +K DL
Sbjct: 2303 LIFANKQDL 2277
>04138
          Length = 800

 Score = 31.2 bits (69), Expect = 0.31,   Method: Compositional matrix adjust.
 Identities = 15/44 (34%), Positives = 25/44 (56%)
 Frame = +1

Query: 15  GDSTVGKSCLIRRFTEGRFAQVSDPTVGVDFFSRLVEIEPGKRI 58
           G    G+  +IR     RFA++     G+D F RL++++P +RI
Sbjct: 439 GALAAGRKNIIR----DRFARILKDPYGLDLFERLLKMDPSQRI 558
>25796
          Length = 422

 Score = 31.2 bits (69), Expect = 0.33,   Method: Compositional matrix adjust.
 Identities = 11/28 (39%), Positives = 17/28 (60%)
 Frame = -1

Query: 1  MEAIWLYQFRLIVIGDSTVGKSCLIRRF 28
          M   + Y F+ ++IG +  GKSCL+  F
Sbjct: 89 MSETYDYLFKFLIIGSAGSGKSCLLHHF 6
>14788
          Length = 634

 Score = 29.3 bits (64), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 10/33 (30%), Positives = 20/33 (60%)
 Frame = -1

Query: 86  LLLFDITNRRSFQNVHEWLEETKVHVQPYQIVF 118
           L+ +  ++  +F N+  WL    VHV+ +Q++F
Sbjct: 556 LMFYFFSSSCAFVNLSSWLLHCNVHVKSFQLLF 458
>24352
          Length = 494

 Score = 28.5 bits (62), Expect = 2.2,   Method: Compositional matrix adjust.
 Identities = 10/33 (30%), Positives = 20/33 (60%)
 Frame = -1

Query: 86  LLLFDITNRRSFQNVHEWLEETKVHVQPYQIVF 118
           L+ + +++  +F N+  WL    VHV  +Q++F
Sbjct: 422 LMFYFLSSSCAFVNLSSWLLHCNVHVXLFQLLF 324
>09700
          Length = 1855

 Score = 27.7 bits (60), Expect = 3.7,   Method: Compositional matrix adjust.
 Identities = 18/59 (30%), Positives = 27/59 (45%), Gaps = 12/59 (20%)
 Frame = -1

Query: 118  FVLVGHKCDLDT------------QRQVTRHEAEKLAAAYGMKYIETSARDAINVEKAF 164
             VLVG + DL              ++ V+  +A KLA   G  Y+E SA    N+++ F
Sbjct: 1810 LVLVGTQSDLRNDVKVLIELAKYKEKPVSEDDASKLAHQLGASYVECSALTQKNLKEMF 1634
>34156
          Length = 348

 Score = 27.3 bits (59), Expect = 4.1,   Method: Compositional matrix adjust.
 Identities = 22/69 (31%), Positives = 37/69 (53%), Gaps = 10/69 (14%)
 Frame = -1

Query: 7   YQFRLIVIGDSTVGKSCLIRR------FTEGRFAQVSDP---TVGVDFFSRLVEIEP-GK 56
           ++F L+V+G+S +GKS L+        + E      S+    TV +D  +  VEIE  G 
Sbjct: 201 FEFTLMVVGESGLGKSTLVNSLFLTDLYPERHIPSASEKIQQTVKID--ASTVEIEERGV 28

Query: 57  RIKLQIWDT 65
           +++L + DT
Sbjct: 27  KLRLTVVDT 1
>07562
          Length = 905

 Score = 27.3 bits (59), Expect = 5.2,   Method: Compositional matrix adjust.
 Identities = 10/24 (41%), Positives = 17/24 (70%)
 Frame = -2

Query: 157 AINVEKAFTDLTRDIYELVKRGEI 180
           AIN+ K  TD T+D+Y+++   +I
Sbjct: 640 AINLHKKMTDTTKDLYQMLATIQI 569
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|63691573|ref|XP_128374.5| PREDICTED: zinc finger
protein 294 isoform 1 [Mus musculus]
         (1767 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

39146                                                                 146   6e-35
31593                                                                  38   0.036
27278                                                                  34   0.51 
06846                                                                  32   1.8  
>39146
          Length = 578

 Score =  146 bits (369), Expect = 6e-35,   Method: Compositional matrix adjust.
 Identities = 61/111 (54%), Positives = 81/111 (72%)
 Frame = -2

Query: 1657 YPLGSITVESGKRIGVAVQQWRNWMLQLSTYLTHQNGSIMEGLALWKNNVDKRFEGVEDC 1716
            +PLG I+V++ +   V + QW   +LQ++ +L HQNG I+EGL LWK N+DK+ EGVE+C
Sbjct: 577  FPLGEISVDAERHAVVKLAQWDRLLLQVNVFLQHQNGPIIEGLKLWKRNIDKKLEGVEEC 398

Query: 1717 MICFSVIHGFNYSLPKKACRTCKKKFHSACLYKWFTSSNKSTCPLCRETFF 1767
             IC++VIH  +  LP+  C TCKKKFHS+CLYKW  SS  +TCPLCR  FF
Sbjct: 397  FICYAVIHATSLDLPRIPCATCKKKFHSSCLYKWLNSSQNATCPLCRSVFF 245
>31593
          Length = 646

 Score = 38.1 bits (87), Expect = 0.036,   Method: Composition-based stats.
 Identities = 15/29 (51%), Positives = 17/29 (58%), Gaps = 3/29 (10%)
 Frame = +3

Query: 1738 CKKKFHSACLYKWFTSS---NKSTCPLCR 1763
            C+K  HS CL  WF  S   N  TCP+CR
Sbjct: 363  CRKNLHSDCLASWFAHSIERNMRTCPICR 449
>27278
          Length = 385

 Score = 34.3 bits (77), Expect = 0.51,   Method: Compositional matrix adjust.
 Identities = 20/54 (37%), Positives = 29/54 (53%), Gaps = 2/54 (3%)
 Frame = +1

Query: 1715 DCMICFSVIHGFNYSLPKKACRT--CKKKFHSACLYKWFTSSNKSTCPLCRETF 1766
            +C IC+S   G    +P KAC    C + FH +CLY+W  S      P C+++F
Sbjct: 127  ECGICYSYRLGDE--IPDKACDDAHCAQPFHHSCLYEWLRSL-----PSCQQSF 267
>06846
          Length = 1152

 Score = 32.3 bits (72), Expect = 1.8,   Method: Compositional matrix adjust.
 Identities = 10/27 (37%), Positives = 13/27 (48%)
 Frame = +2

Query: 1738 CKKKFHSACLYKWFTSSNKSTCPLCRE 1764
            CK  FH  C++ W        CP CR+
Sbjct: 455  CKHLFHKRCIHVWLMKYKNKDCPFCRQ 535
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6679012|ref|NP_032698.1| nucleosome assembly protein
1-like 4 [Mus musculus]
         (375 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

10418                                                                 144   6e-35
25304                                                                  49   5e-06
12559                                                                  33   0.19 
>10418
          Length = 974

 Score =  144 bits (363), Expect = 6e-35,   Method: Compositional matrix adjust.
 Identities = 75/139 (53%), Positives = 87/139 (62%), Gaps = 2/139 (1%)
 Frame = +1

Query: 204 FVLEFHFEPNDYFTNPVLTKTYKMKSEPDKADPFSFEGPEIVDCDGCTIDWXXXXXXXXX 263
           F LEFHFEPN+YFT  VLTK Y M+ E D  DPFS+EGPEI+ C GC I W         
Sbjct: 1   FTLEFHFEPNEYFTESVLTKQYTMRFEQDPTDPFSYEGPEIIKCVGCPITWNKGKNVTVK 180

Query: 264 XXXXXXXXXXXXXXRTITKQVPNESFFNFF--SPLKASGDGESLDEDSEFTLASDFEIGH 321
                         RT+TK V N+SFFNFF    +    + + +DED E  LA+DFEIGH
Sbjct: 181 VVKKKQKHKGKGLTRTVTKTVQNDSFFNFFDPPEVPEPENEDDVDEDMEQLLATDFEIGH 360

Query: 322 FFRERIVPRAVLYFTGEAI 340
           F RERIVPRAVLYFTGEA+
Sbjct: 361 FIRERIVPRAVLYFTGEAM 417
>25304
          Length = 525

 Score = 48.5 bits (114), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 46/188 (24%), Positives = 74/188 (39%), Gaps = 1/188 (0%)
 Frame = -2

Query: 57  ETLPKAVKRRINALKQLQVRCAHIEAKFYEEVHDLERKYAALYQPLFDKRREFITGDVEP 116
           E   K  +  I  + ++Q     +  +  EE+  +E+KY  L QP F KR++ I+     
Sbjct: 476 EQADKDQQEAIERIDEVQNDIDRLNEQASEEILTVEQKYNKLRQPFFKKRQDLISK---- 309

Query: 117 TDAESAWHSENEEEDKLAGDMKNKVVIAEKEAATVEELNPKGIPEFWFTIFRNVDMLSEL 176
                                                     IP FW T F N   +S L
Sbjct: 308 ------------------------------------------IPNFWVTSFVNHPQVSAL 255

Query: 177 VQEYDEPILKHLQDIKVK-FSDPGQPMSFVLEFHFEPNDYFTNPVLTKTYKMKSEPDKAD 235
           + E DE  L+ L  ++V+ F D      + ++FHFE N +F N V+ K + +    D  +
Sbjct: 254 LTEDDEEALQFLSVVEVQEFEDIK--SGYTIKFHFESNPFFDNEVICKEFHLN---DSGE 90

Query: 236 PFSFEGPE 243
           P S + P+
Sbjct: 89  P-SIQSPQ 69
>12559
          Length = 519

 Score = 33.1 bits (74), Expect = 0.19,   Method: Compositional matrix adjust.
 Identities = 14/15 (93%), Positives = 15/15 (100%)
 Frame = +3

Query: 326 RIVPRAVLYFTGEAI 340
           RIVPRAVLYFTGEA+
Sbjct: 3   RIVPRAVLYFTGEAM 47
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|110815853|ref|NP_001036076.1| ceruloplasmin isoform a
[Mus musculus]
         (1086 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

22312                                                                  85   8e-35
35962                                                                  74   9e-21
19569                                                                  47   3e-05
28511                                                                  36   0.094
18452                                                                  32   0.98 
>22312
          Length = 960

 Score = 84.7 bits (208), Expect(3) = 8e-35,   Method: Compositional matrix adjust.
 Identities = 43/104 (41%), Positives = 66/104 (63%)
 Frame = +2

Query: 913  LLFLVFDENESWYLDDNIKTYSEHPEKVNKDNEEFLESNKMHAINGKMFGNLQGLTMHVK 972
            L+F +FDENESWYLD NI  + +   K++ D   F ESN MHAING ++ N   +     
Sbjct: 197  LVFKIFDENESWYLDHNIARFGQPDSKLDPD---FEESNLMHAINGYIYNNNPPIKFPQG 367

Query: 973  DEVNWYVMGMGNEIDLHTVHFHGHSFQYKHRGVYSSDVFDLFPG 1016
              V+++++ +GN++D+H+VH+HG+       G ++ DV  LFPG
Sbjct: 368  SIVDFHLITLGNQVDIHSVHWHGNPVLLFRTGQHTRDVAQLFPG 499

 Score = 52.8 bits (125), Expect(3) = 8e-35,   Method: Composition-based stats.
 Identities = 25/57 (43%), Positives = 33/57 (57%)
 Frame = +1

Query: 851 TYTWQIPERSGAGREDSACIPWAYYSTVDRVKDLYSGLIGPLIVCRKSYVKVFSPKK 907
           TY + +P        D  CI  AYYS VD VKD+ SGLIGPL++C+   +   + KK
Sbjct: 1   TYKYTVPIEFAPADGDPECINQAYYSAVDMVKDVNSGLIGPLVICKPGSLNKKTGKK 171

 Score = 49.7 bits (117), Expect(3) = 8e-35,   Method: Compositional matrix adjust.
 Identities = 22/39 (56%), Positives = 26/39 (66%)
 Frame = +3

Query: 1018 YQTLEMFPQTPGTWLLHCHVTDHVHAGMATTYTVLPVEQ 1056
            Y+T+ M     GTWLLHCHV DH+ AGM T YTV   +Q
Sbjct: 504  YETVRMNATFEGTWLLHCHVHDHLDAGMETVYTVSAAKQ 620

 Score = 82.0 bits (201), Expect(3) = 4e-29,   Method: Composition-based stats.
 Identities = 42/116 (36%), Positives = 64/116 (55%), Gaps = 3/116 (2%)
 Frame = +2

Query: 208 KEKNIDQEFVLMFSVVDENLSWYLEDNIKTFCSEPEKVDKDNEDFQESNRMYSINGYTFG 267
           K   +D+   L+F + DEN SWYL+ NI  F     K+D D   F+ESN M++INGY + 
Sbjct: 167 KRTGVDRAISLVFKIFDENESWYLDHNIARFGQPDSKLDPD---FEESNLMHAINGYIYN 337

Query: 268 SLPGLSMCAADRVKWYLFGMGNEVDVHSAFFHGQAL---TSRNYQTDIINLFPATL 320
           + P +       V ++L  +GN+VD+HS  +HG  +    +  +  D+  LFP  L
Sbjct: 338 NNPPIKFPQGSIVDFHLITLGNQVDIHSVHWHGNPVLLFRTGQHTRDVAQLFPGIL 505

 Score = 57.8 bits (138), Expect(3) = 4e-29,   Method: Composition-based stats.
 Identities = 25/48 (52%), Positives = 34/48 (70%)
 Frame = +1

Query: 163 EPSPGEGDSNCVTRIYHSHVDAPKDIASGLIGPLILCKKGSLYKEKEK 210
           E +P +GD  C+ + Y+S VD  KD+ SGLIGPL++CK GSL K+  K
Sbjct: 25  EFAPADGDPECINQAYYSAVDMVKDVNSGLIGPLVICKPGSLNKKTGK 168

 Score = 28.1 bits (61), Expect(3) = 4e-29,   Method: Compositional matrix adjust.
 Identities = 11/29 (37%), Positives = 16/29 (55%)
 Frame = +3

Query: 325 MVAQNPGVWMLSCQNLNHLKAGLQAFFQV 353
           M A   G W+L C   +HL AG++  + V
Sbjct: 519 MNATFEGTWLLHCHVHDHLDAGMETVYTV 605

 Score = 85.1 bits (209), Expect = 2e-16,   Method: Composition-based stats.
 Identities = 46/114 (40%), Positives = 66/114 (57%), Gaps = 3/114 (2%)
 Frame = +2

Query: 564 GRQKDVDKEFYLFPTVFDENESLLLDDNIRMFTTAPDQVDKEDEDFQESNKMHSMNGFMY 623
           G++  VD+   L   +FDENES  LD NI  F   PD   K D DF+ESN MH++NG++Y
Sbjct: 164 GKRTGVDRAISLVFKIFDENESWYLDHNIARFGQ-PDS--KLDPDFEESNLMHAINGYIY 334

Query: 624 GNQPGLNMCLGESIVWYLFSAGNEADVHGIYFSGNTYL---SKGERRDTANLFP 674
            N P +    G  + ++L + GN+ D+H +++ GN  L   +    RD A LFP
Sbjct: 335 NNNPPIKFPQGSIVDFHLITLGNQVDIHSVHWHGNPVLLFRTGQHTRDVAQLFP 496

 Score = 67.8 bits (164), Expect = 2e-11,   Method: Composition-based stats.
 Identities = 34/71 (47%), Positives = 45/71 (63%)
 Frame = +1

Query: 511 TYEWTVPKEMGPTYADPVCLSKMYYSGVDPTKDIFTGLIGPMKICKKGSLLADGRQKDVD 570
           TY++TVP E  P   DP C+++ YYS VD  KD+ +GLIGP+ ICK GSL     +KD  
Sbjct: 1   TYKYTVPIEFAPADGDPECINQAYYSAVDMVKDVNSGLIGPLVICKPGSLNKKTGKKDRR 180

Query: 571 KEFYLFPTVFD 581
            + + FP V D
Sbjct: 181 GQGH-FPRVQD 210

 Score = 30.8 bits (68), Expect = 3.3,   Method: Compositional matrix adjust.
 Identities = 17/53 (32%), Positives = 27/53 (50%), Gaps = 4/53 (7%)
 Frame = +3

Query: 668 DTANLFPHKSL----TLLMNPDTKGTFDVECLTTDHYTGGMKQKYTVNQCQRQ 716
            T   +P  SL    T+ MN   +GT+ + C   DH   GM+  YTV+  +++
Sbjct: 465 STRGTWPSSSLAFYETVRMNATFEGTWLLHCHVHDHLDAGMETVYTVSAAKQR 623
>35962
          Length = 554

 Score = 73.6 bits (179), Expect(2) = 9e-21,   Method: Compositional matrix adjust.
 Identities = 38/102 (37%), Positives = 51/102 (50%), Gaps = 1/102 (0%)
 Frame = +2

Query: 288 GNEVDVHSAFFHGQALTSRNYQTDIINLFPATLIDAYMVAQNPGVWMLSCQNLNHLKAGL 347
           G+E DVH+ + HGQ LT  + +              +M A+NPG W +SCQ   H   G 
Sbjct: 2   GSEFDVHTVYMHGQPLTLLDTRRSSTYAIAGYFRTMFMKAENPGQWSVSCQTSEHYNGGE 181

Query: 348 QAFFQVRDCNKPSPEDNIQDRHV-RHYYIAAEEVIWNYAPSG 388
           QA F V+ C   +  D      V R +Y+ AEE  W+YAPS 
Sbjct: 182 QALFNVQQCGLDTDHDIALTXGVDRTFYLQAEEEYWDYAPSA 307

 Score = 45.8 bits (107), Expect(2) = 9e-21,   Method: Composition-based stats.
 Identities = 22/55 (40%), Positives = 33/55 (60%)
 Frame = +3

Query: 401 ESDSRVFFEQGATRIGGSYKKMAYREYTDGSFTNRKQRGPDEEHLGILGPVIWAE 455
           E+ + +F       +G  YKK+ Y +YTD +F +R  R   + +LG+LGPVI AE
Sbjct: 342 EAPAYIFTTSTGPYLGTIYKKVRYHQYTDSTFRHRVIRPYQDRYLGVLGPVIAAE 506

 Score = 61.6 bits (148), Expect(2) = 9e-19,   Method: Compositional matrix adjust.
 Identities = 36/104 (34%), Positives = 52/104 (50%), Gaps = 2/104 (1%)
 Frame = +2

Query: 645 GNEADVHGIYFSGNTYLSKGERRDTANLFPHKSLTLLMNPDTKGTFDVECLTTDHYTGGM 704
           G+E DVH +Y  G        RR +         T+ M  +  G + V C T++HY GG 
Sbjct: 2   GSEFDVHTVYMHGQPLTLLDTRRSSTYAIAGYFRTMFMKAENPGQWSVSCQTSEHYNGGE 181

Query: 705 KQKYTVNQCQRQFE-DFTVYLG-ERTYYVAAVEVEWDYSPSRAW 746
           +  + V QC    + D  +  G +RT+Y+ A E  WDY+PS AW
Sbjct: 182 QALFNVQQCGLDTDHDIALTXGVDRTFYLQAEEEYWDYAPS-AW 310

 Score = 51.2 bits (121), Expect(2) = 9e-19,   Method: Composition-based stats.
 Identities = 27/64 (42%), Positives = 39/64 (60%), Gaps = 10/64 (15%)
 Frame = +3

Query: 756 QNVSNVFLDKEEF----------FIGSKYKKVVYRQFTDSSFREQVKRRAEDEHLGILGP 805
           Q++   FLD+E            ++G+ YKKV Y Q+TDS+FR +V R  +D +LG+LGP
Sbjct: 312 QSLRQKFLDREAPAYIFTTSTGPYLGTIYKKVRYHQYTDSTFRHRVIRPYQDRYLGVLGP 491

Query: 806 PIHA 809
            I A
Sbjct: 492 VIAA 503

 Score = 40.8 bits (94), Expect = 0.003,   Method: Composition-based stats.
 Identities = 23/50 (46%), Positives = 28/50 (56%), Gaps = 3/50 (6%)
 Frame = +3

Query: 54  FYLQNGPDRIGRKYKKALYFEYTDGTFSKTIDKP---AWLGFLGPVIKAE 100
           F    GP  +G  YKK  Y +YTD TF   + +P    +LG LGPVI AE
Sbjct: 360 FTTSTGP-YLGTIYKKVRYHQYTDSTFRHRVIRPYQDRYLGVLGPVIAAE 506

 Score = 37.0 bits (84), Expect = 0.044,   Method: Compositional matrix adjust.
 Identities = 19/72 (26%), Positives = 33/72 (45%), Gaps = 3/72 (4%)
 Frame = +2

Query: 983  GNEIDLHTVHFHGHSFQY---KHRGVYSSDVFDLFPGTYQTLEMFPQTPGTWLLHCHVTD 1039
            G+E D+HTV+ HG        +    Y+        G ++T+ M  + PG W + C  ++
Sbjct: 2    GSEFDVHTVYMHGQPLTLLDTRRSSTYA------IAGYFRTMFMKAENPGQWSVSCQTSE 163

Query: 1040 HVHAGMATTYTV 1051
            H + G    + V
Sbjct: 164  HYNGGEQALFNV 199
>19569
          Length = 601

 Score = 47.4 bits (111), Expect = 3e-05,   Method: Composition-based stats.
 Identities = 20/38 (52%), Positives = 24/38 (63%)
 Frame = -2

Query: 1016 GTYQTLEMFPQTPGTWLLHCHVTDHVHAGMATTYTVLP 1053
            G ++T+ M     G WLLHCHV DH+ AGM T Y V P
Sbjct: 600  GVFETVWMNTTRAGKWLLHCHVHDHLTAGMETVYMVNP 487
>28511
          Length = 487

 Score = 35.8 bits (81), Expect = 0.094,   Method: Compositional matrix adjust.
 Identities = 19/43 (44%), Positives = 22/43 (51%), Gaps = 9/43 (20%)
 Frame = -1

Query: 1028 PGTWLLHCHVTD---------HVHAGMATTYTVLPVEQVSSQS 1061
            P  W LHCH+           H HAG  T YTV+PV+  S QS
Sbjct: 406  PTAWHLHCHIQHSLDLFECWGHTHAGEHTVYTVVPVDPTSHQS 278
>18452
          Length = 620

 Score = 32.3 bits (72), Expect = 0.98,   Method: Composition-based stats.
 Identities = 20/78 (25%), Positives = 30/78 (38%), Gaps = 9/78 (11%)
 Frame = +1

Query: 977  WYVMGMGNEIDLHTVHFH-GHSFQYKHRGVY--------SSDVFDLFPGTYQTLEMFPQT 1027
            ++V+G+G   D      +  H+     RG+         + D   +    Y  L      
Sbjct: 190  FHVIGLGRSPDSSVKKINLKHALDLDRRGLLHRQYNLPPTKDTIAVPNNGYVVLRFRADN 369

Query: 1028 PGTWLLHCHVTDHVHAGM 1045
            PG WL HCH   H+  GM
Sbjct: 370  PGFWLFHCHFLFHIVIGM 423

 Score = 30.0 bits (66), Expect = 5.3,   Method: Composition-based stats.
 Identities = 11/27 (40%), Positives = 14/27 (51%)
 Frame = +1

Query: 327 AQNPGVWMLSCQNLNHLKAGLQAFFQV 353
           A NPG W+  C  L H+  G+    QV
Sbjct: 361 ADNPGFWLFHCHFLFHIVIGMNLILQV 441
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|188528681|ref|NP_062639.3| ADP-ribosylation
factor-like 6 [Mus musculus]
         (186 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

09827                                                                 142   8e-35
08153                                                                 141   2e-34
10862                                                                  93   7e-20
11378                                                                  88   2e-18
18208                                                                  76   7e-15
33605                                                                  75   2e-14
32860                                                                  74   3e-14
18949                                                                  62   1e-10
15662                                                                  52   2e-07
06991                                                                  50   5e-07
11965                                                                  45   2e-05
35581                                                                  42   1e-04
19006                                                                  36   0.008
34468                                                                  36   0.008
13750                                                                  35   0.014
29196                                                                  35   0.022
19506                                                                  35   0.024
33794                                                                  34   0.029
14775                                                                  33   0.051
01570                                                                  29   1.1  
33380                                                                  29   1.3  
14433                                                                  28   2.7  
29813                                                                  26   8.4  
23882                                                                  26   8.9  
>09827
          Length = 1201

 Score =  142 bits (358), Expect = 8e-35,   Method: Compositional matrix adjust.
 Identities = 68/170 (40%), Positives = 116/170 (68%)
 Frame = -3

Query: 17   EVHVLCLGLDNSGKTTIINKLKPSNAQSQDIVPTIGFSIEKFKSSSLSFTVFDMSGQGRY 76
            ++ +L +GLD +GKTTI+ KLK     +   +PTIGF++E  +  ++SFTV+D+ GQ + 
Sbjct: 1115 DMRILMVGLDAAGKTTILYKLKLGEIVT--TIPTIGFNVETVEYKNISFTVWDVGGQDKI 942

Query: 77   RNLWEHYYKDGQAIIFVIDSSDKLRMVVAKEELDTLLNHPDIKHRRIPILFFANKMDLRD 136
            R LW HY+++ Q +IFV+DS+DK R+  A+EEL  +LN  ++  R   +L FANK DL  
Sbjct: 941  RPLWRHYFQNTQGLIFVVDSNDKERVQEAREELTRMLNEDEL--RDAVLLVFANKQDLPH 768

Query: 137  SVTSVKVSQLLCLESIKDKPWHICASDAIKGEGLQEGVDWLQDQIQAVKT 186
            ++ + ++++ L L  ++++ W+I ++ A  G+GL EG+DWL +Q++  K+
Sbjct: 767  AMATAEITEKLGLHGLRNRTWYIQSTCATTGDGLYEGLDWLSNQLKNNKS 618
>08153
          Length = 1703

 Score =  141 bits (355), Expect = 2e-34,   Method: Compositional matrix adjust.
 Identities = 70/166 (42%), Positives = 112/166 (67%)
 Frame = +1

Query: 17  EVHVLCLGLDNSGKTTIINKLKPSNAQSQDIVPTIGFSIEKFKSSSLSFTVFDMSGQGRY 76
           EV +L +GLD +GKTTI+ KLK     +   +PTIGF++E  +  ++SFTV+D+ GQ + 
Sbjct: 82  EVRILMVGLDAAGKTTILYKLKLGEIVTT--IPTIGFNVETVEYKNISFTVWDVGGQDKI 255

Query: 77  RNLWEHYYKDGQAIIFVIDSSDKLRMVVAKEELDTLLNHPDIKHRRIPILFFANKMDLRD 136
           R LW HY+++ Q +IFV+DS+D+ R+  AKEEL  +LN  D+  R   IL FANK DL +
Sbjct: 256 RPLWRHYFQNTQGLIFVVDSNDRERINEAKEELARMLNEDDL--RDAIILVFANKQDLPN 429

Query: 137 SVTSVKVSQLLCLESIKDKPWHICASDAIKGEGLQEGVDWLQDQIQ 182
           + ++ +V+  L L ++K + W++ A+ A  G+G+ EG++WL   ++
Sbjct: 430 AYSASEVTAHLGLANLKGRKWYMQATCATSGDGMYEGLEWLSTTLK 567
>10862
          Length = 2896

 Score = 92.8 bits (229), Expect = 7e-20,   Method: Compositional matrix adjust.
 Identities = 46/117 (39%), Positives = 71/117 (60%)
 Frame = -3

Query: 61   SSLSFTVFDMSGQGRYRNLWEHYYKDGQAIIFVIDSSDKLRMVVAKEELDTLLNHPDIKH 120
                F V+D+ GQ + R LW HYY   Q +IFV+D +D+ R+  A++EL  ++N  D + 
Sbjct: 2492 QECQFNVWDVGGQDKIRPLWRHYYTGTQGLIFVVDCADRDRIDEARQELHRIIN--DREM 2319

Query: 121  RRIPILFFANKMDLRDSVTSVKVSQLLCLESIKDKPWHICASDAIKGEGLQEGVDWL 177
            R   IL FANK DL D++   ++ + L L  ++D+ W++  S A  G+GL EG+ WL
Sbjct: 2318 RDAIILIFANKQDLPDAMKPHEIQEKLGLTRLRDRNWYVQPSCATTGDGLCEGLTWL 2148

 Score = 44.7 bits (104), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 27/68 (39%), Positives = 41/68 (60%), Gaps = 1/68 (1%)
 Frame = -1

Query: 17   EVHVLCLGLDNSGKTTIINKLKPSNAQSQDIVPTIGFSIEKFKSSSLSF-TVFDMSGQGR 75
            E+ +L LGLD +GKTT++ K+K    QS   +PT+GF++E     ++SF  V  MSG   
Sbjct: 2617 EMRILMLGLDAAGKTTLLYKMKL--GQSVTXIPTVGFNVE-----TVSFKNVNSMSGM*V 2459

Query: 76   YRNLWEHY 83
             R  ++ Y
Sbjct: 2458 GRTKYDRY 2435
>11378
          Length = 1688

 Score = 87.8 bits (216), Expect = 2e-18,   Method: Compositional matrix adjust.
 Identities = 50/174 (28%), Positives = 85/174 (48%), Gaps = 12/174 (6%)
 Frame = +3

Query: 20  VLCLGLDNSGKTTIINKLKPSNAQSQDIVPTIGFSIEKFKSSSLSFTVFDMSGQGRYRNL 79
           ++ LGLDN+GKTT+++ LK         VPT+  + E+     + FT FD+ G  + R +
Sbjct: 330 LVFLGLDNAGKTTLLHMLKDDKMAQH--VPTLHPTSEELSMGGMRFTTFDLGGHRQARRV 503

Query: 80  WEHYYKDGQAIIFVIDSSDKLRMVVAKEELDTLLNHPDIKHRRIPILFFANKMDLRDSVT 139
           W+ Y+     I+F++D  D+ R+V AK ELD+L+    + +   PIL   NK+D   + +
Sbjct: 504 WKDYFPAVDGIVFLVDVHDRERLVEAKAELDSLMTDEQVAN--APILVLGNKIDKPGAAS 677

Query: 140 SVKVSQLLCLESIK------------DKPWHICASDAIKGEGLQEGVDWLQDQI 181
             ++     L S+              +P  +     +K +G  EG  W+   I
Sbjct: 678 EEEIRHWFGLNSLTTGKGTVARGELPGRPMELFMCSVLKRQGYGEGFRWMAQYI 839
>18208
          Length = 458

 Score = 76.3 bits (186), Expect = 7e-15,   Method: Compositional matrix adjust.
 Identities = 36/86 (41%), Positives = 56/86 (65%)
 Frame = -1

Query: 17  EVHVLCLGLDNSGKTTIINKLKPSNAQSQDIVPTIGFSIEKFKSSSLSFTVFDMSGQGRY 76
           E+ +L LGLDN+GKTT++ +L  ++     I PT GF+I+  +S      V+D+ GQ R 
Sbjct: 302 ELRILLLGLDNAGKTTLLKQL--ASEDPSHITPTQGFNIKSVQSKGFKLNVWDIGGQRRI 129

Query: 77  RNLWEHYYKDGQAIIFVIDSSDKLRM 102
           R  W++Y+++   +I+VIDSSD  RM
Sbjct: 128 RPYWKNYFENTDLLIYVIDSSDTKRM 51
>33605
          Length = 888

 Score = 75.1 bits (183), Expect = 2e-14,   Method: Compositional matrix adjust.
 Identities = 33/92 (35%), Positives = 57/92 (61%)
 Frame = +1

Query: 17  EVHVLCLGLDNSGKTTIINKLKPSNAQSQDIVPTIGFSIEKFKSSSLSFTVFDMSGQGRY 76
           EV +L LGLDN+GKTTI+ K    +  +  I PT+GF+I+  +       V+D+ GQ   
Sbjct: 496 EVRLLMLGLDNAGKTTILKKFNGEDIDT--ISPTLGFNIKTLEHRGFKLNVWDVGGQQSL 669

Query: 77  RNLWEHYYKDGQAIIFVIDSSDKLRMVVAKEE 108
           R+ W +Y++    +++V+DS+D++R+   K +
Sbjct: 670 RSYWRNYFESTDGLVWVVDSADRMRIADCKRD 765
>32860
          Length = 330

 Score = 74.3 bits (181), Expect = 3e-14,   Method: Compositional matrix adjust.
 Identities = 36/91 (39%), Positives = 56/91 (61%)
 Frame = +2

Query: 80  WEHYYKDGQAIIFVIDSSDKLRMVVAKEELDTLLNHPDIKHRRIPILFFANKMDLRDSVT 139
           W  YY + + II VIDS+D+ R+ + KEEL  +L   ++  R   +L FANK D++  ++
Sbjct: 8   WNTYYSNSEFIIMVIDSTDRERLSITKEELCRMLATEEL--RXAALLVFANKQDIKGCMS 181

Query: 140 SVKVSQLLCLESIKDKPWHICASDAIKGEGL 170
           + ++S  L L S+KD  WHI A   + GEG+
Sbjct: 182 AAEISXQLNLTSVKDHVWHIQACCGLTGEGV 274
>18949
          Length = 414

 Score = 62.0 bits (149), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 31/85 (36%), Positives = 46/85 (54%)
 Frame = +3

Query: 49  PTIGFSIEKFKSSSLSFTVFDMSGQGRYRNLWEHYYKDGQAIIFVIDSSDKLRMVVAKEE 108
           PT   + E+     ++FT FD+ G  + R +W+ Y+     I+F++D  D  R+  AK E
Sbjct: 15  PTGLPTSEELSMGGMTFTTFDLGGHRQARRVWKDYFPAVDGIVFIVDVHDTERITEAKAE 194

Query: 109 LDTLLNHPDIKHRRIPILFFANKMD 133
           LD+LL    I    IP+L   NKMD
Sbjct: 195 LDSLLRDDQIAD--IPVLVLGNKMD 263
>15662
          Length = 455

 Score = 52.0 bits (123), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 30/117 (25%), Positives = 52/117 (44%), Gaps = 12/117 (10%)
 Frame = +2

Query: 77  RNLWEHYYKDGQAIIFVIDSSDKLRMVVAKEELDTLLNHPDIKHRRIPILFFANKMDLRD 136
           R +W+ Y+     I+F++D  D+ R V AK ELD+L+    + +   PIL   NK+D   
Sbjct: 8   RRVWKDYFPAVDGIVFLVDVHDRERFVEAKAELDSLMTDEQVAN--APILVLGNKIDKPG 181

Query: 137 SVTSVKVSQLLCLES------------IKDKPWHICASDAIKGEGLQEGVDWLQDQI 181
           + +  ++     L S            +  +P  +     +K +G  EG  W+   I
Sbjct: 182 AASEDEIRHWFGLHSLTTGKGTVSRGELPGRPLELFMCSVLKRQGYGEGFRWMAQYI 352
>06991
          Length = 1860

 Score = 50.1 bits (118), Expect = 5e-07,   Method: Compositional matrix adjust.
 Identities = 20/57 (35%), Positives = 37/57 (64%)
 Frame = -2

Query: 125  ILFFANKMDLRDSVTSVKVSQLLCLESIKDKPWHICASDAIKGEGLQEGVDWLQDQI 181
            ++ FANK D+  ++T  +V+  L L  +K++ + I  + A+KGEGL E ++WL + +
Sbjct: 1829 LMVFANKQDIEGAMTVTEVANSLGLPGLKNRKYQIFKTSAVKGEGLDEAMEWLSNSL 1659
>11965
          Length = 3256

 Score = 44.7 bits (104), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 41/153 (26%), Positives = 63/153 (41%), Gaps = 14/153 (9%)
 Frame = +1

Query: 45  QDI----VPTIGFSIEKFKSSSLSFTVFDMSGQGRYRNLWEHYYKDGQAIIFVIDSSD-- 98
           QDI    V T G     F   +L+F +FD+ GQ   R  W H ++D  AIIF +  S+  
Sbjct: 118 QDILRTRVKTTGIVEVHFSFKNLNFKLFDVGGQRSERKKWIHCFEDVTAIIFCVAMSEYD 297

Query: 99  --------KLRMVVAKEELDTLLNHPDIKHRRIPILFFANKMDLRDSVTSVKVSQLLCLE 150
                     RM  + +  D++ N+         I+ F NK DL +             E
Sbjct: 298 QVLHEDETTNRMQESLKLFDSICNNKWFTD--TSIILFLNKKDLFE-------------E 432

Query: 151 SIKDKPWHICASDAIKGEGLQEGVDWLQDQIQA 183
            IK  P  +C  +    +  +E   ++Q Q +A
Sbjct: 433 KIKKSPLTVCFPEYTGKQTYEEVAAYIQAQFEA 531
>35581
          Length = 364

 Score = 42.4 bits (98), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 25/89 (28%), Positives = 45/89 (50%), Gaps = 8/89 (8%)
 Frame = +2

Query: 23  LGLDNSGKTTIINKLKP--------SNAQSQDIVPTIGFSIEKFKSSSLSFTVFDMSGQG 74
           LG    GKT ++N+L          ++  +  ++ T+  +     S  L    +D +GQ 
Sbjct: 62  LGDAGVGKTCLLNRLATDKFLDSPLTSLTTASLLTTVTLTSGVMASVDL----WDTAGQE 229

Query: 75  RYRNLWEHYYKDGQAIIFVIDSSDKLRMV 103
           RYR+L   YY+D +A++ V D+  KL++ 
Sbjct: 230 RYRSLTSSYYRDTKAVLIVYDAEHKLKLT 316
>19006
          Length = 568

 Score = 36.2 bits (82), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 25/81 (30%), Positives = 37/81 (45%), Gaps = 4/81 (4%)
 Frame = -2

Query: 60  SSSLSFTVFDMSGQGRYRNLWEHYYKDGQAII--FVIDSSDKLRMVVAKEELDTLLNHPD 117
           S  +   ++D +GQ  Y  L    Y D   I+  F IDS D L  +  K         P+
Sbjct: 303 SKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKW-------TPE 145

Query: 118 IKH--RRIPILFFANKMDLRD 136
           ++H    +PI+   NK DLR+
Sbjct: 144 VRHFCPNVPIILVGNKKDLRN 82
>34468
          Length = 1502

 Score = 36.2 bits (82), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 23/85 (27%), Positives = 42/85 (49%), Gaps = 9/85 (10%)
 Frame = +1

Query: 20  VLCLGLDNSGKTTIINKLK----PSNAQSQDIVPTIGFSIE----KFKSSSLSFTVFDMS 71
           ++ +G  N GKT +  +      P   ++     TIG        +  S  L   ++D +
Sbjct: 502 IIVIGDSNVGKTCLTYRFCLGKFPDKTEA-----TIGVDFREKSIQVDSEHLKLQLWDTA 666

Query: 72  GQGRYR-NLWEHYYKDGQAIIFVID 95
           GQ R+R ++ +HYY++  A++FV D
Sbjct: 667 GQERFRKSMVQHYYRNVHAVVFVYD 741
>13750
          Length = 503

 Score = 35.4 bits (80), Expect = 0.014,   Method: Compositional matrix adjust.
 Identities = 23/97 (23%), Positives = 45/97 (46%), Gaps = 7/97 (7%)
 Frame = -2

Query: 48  VPTIGFSIEKFKSS-----SLSFTVFDMSGQGRYRNLWEHYYKDGQAIIFVIDSSDKLRM 102
           +PTI     +F  S     ++ +T++D  G   YR+LW  +++  Q  + V D + +   
Sbjct: 451 MPTIAVLCSEFNESRTDPLNVRYTLWDTGGAETYRSLWVSHFRGAQVALLVYDVTCEWSF 272

Query: 103 VVAKEELDTLL--NHPDIKHRRIPILFFANKMDLRDS 137
           + A       L  N P+ +     ++F  +K DL ++
Sbjct: 271 LTATTVWRKALMKNIPEAQ-----VIFVGSKTDLEEN 176
>29196
          Length = 431

 Score = 34.7 bits (78), Expect = 0.022,   Method: Compositional matrix adjust.
 Identities = 20/60 (33%), Positives = 30/60 (50%)
 Frame = -2

Query: 62  SLSFTVFDMSGQGRYRNLWEHYYKDGQAIIFVIDSSDKLRMVVAKEELDTLLNHPDIKHR 121
           +L+F +FD+ GQ   R  W H ++D  AIIF           VA  E D +L+  +  +R
Sbjct: 226 NLNFKLFDVGGQRSERKKWIHCFEDVTAIIF----------CVAMSEYDQVLHEDETTNR 77
>19506
          Length = 421

 Score = 34.7 bits (78), Expect = 0.024,   Method: Compositional matrix adjust.
 Identities = 17/39 (43%), Positives = 25/39 (64%)
 Frame = -3

Query: 18  VHVLCLGLDNSGKTTIINKLKPSNAQSQDIVPTIGFSIE 56
           V V+  GLD +GKTT++  LK     +   +PTIGF++E
Sbjct: 134 VTVIYFGLDAAGKTTLLYNLKLGEVVTT--IPTIGFNVE 24
>33794
          Length = 779

 Score = 34.3 bits (77), Expect = 0.029,   Method: Compositional matrix adjust.
 Identities = 23/102 (22%), Positives = 42/102 (41%), Gaps = 2/102 (1%)
 Frame = -1

Query: 35  NKLKPSNAQSQDIVPTIGFSIEK--FKSSSLSFTVFDMSGQGRYRNLWEHYYKDGQAIIF 92
           N     N  +  I+ T+ +       +   +   ++D SGQGR+  +   Y +  Q II 
Sbjct: 740 NPFCSGNDCTSHILQTVAYKTTTILLEGKRVKLQIWDTSGQGRFCTIIRSYSRGAQGIIL 561

Query: 93  VIDSSDKLRMVVAKEELDTLLNHPDIKHRRIPILFFANKMDL 134
           V D ++K       + +D  L   +     IP +   N++ L
Sbjct: 560 VYDITNKWSF----DGIDRWLKEVEEHAPGIPKVLVGNRLHL 447
>14775
          Length = 380

 Score = 33.5 bits (75), Expect = 0.051,   Method: Compositional matrix adjust.
 Identities = 18/86 (20%), Positives = 38/86 (44%), Gaps = 5/86 (5%)
 Frame = -2

Query: 48  VPTIGFSIEKFKSS-----SLSFTVFDMSGQGRYRNLWEHYYKDGQAIIFVIDSSDKLRM 102
           +PTI     +F  S     ++ +T++D  G   YR+LW  +++  Q  + V D + +   
Sbjct: 328 MPTIAVLCSEFNESRTDPLNVRYTLWDTGGAETYRSLWVSHFRGAQVALLVYDVTCERGQ 149

Query: 103 VVAKEELDTLLNHPDIKHRRIPILFF 128
             A +   T      +  + +  +F+
Sbjct: 148 AFATQCGYTFFETSSVTGKNVDAVFW 71
>01570
          Length = 1108

 Score = 28.9 bits (63), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 24/74 (32%), Positives = 35/74 (47%), Gaps = 8/74 (10%)
 Frame = +3

Query: 20  VLCL--GLDNSGKTTIINKLKPSNAQSQDIVPTI-----GFSIEKFKSSSL-SFTVFDMS 71
           V+C+  GL N   T   +  K SN     ++PTI         +K  S  L  +T+  M 
Sbjct: 282 VICVS*GL*N*SSTLFWD*AKISNQNKTKLLPTIPKYENNIRAQKNISKILKEYTIGIMQ 461

Query: 72  GQGRYRNLWEHYYK 85
            + RYRNLW  ++K
Sbjct: 462 *KSRYRNLWNFFFK 503
>33380
          Length = 282

 Score = 28.9 bits (63), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 15/70 (21%), Positives = 30/70 (42%)
 Frame = +3

Query: 67  VFDMSGQGRYRNLWEHYYKDGQAIIFVIDSSDKLRMVVAKEELDTLLNHPDIKHRRIPIL 126
           ++D +GQ RYR +   YY+     I + D +++      ++    +  +         ++
Sbjct: 72  IWDTAGQERYRTITTAYYRGAMGFILMYDVTNEESFNAVQDWCTQIKTYS---WDNAQVV 242

Query: 127 FFANKMDLRD 136
              NK DL D
Sbjct: 243 LVGNKCDLED 272
>14433
          Length = 520

 Score = 27.7 bits (60), Expect = 2.7,   Method: Compositional matrix adjust.
 Identities = 13/41 (31%), Positives = 24/41 (58%)
 Frame = +3

Query: 18 VHVLCLGLDNSGKTTIINKLKPSNAQSQDIVPTIGFSIEKF 58
          + V  +G  N+GK++IIN LK S A +    P +  ++++ 
Sbjct: 6  IRVGIVGFPNTGKSSIINSLKRSKACTVGATPGVTRAMQEV 128
>29813
          Length = 690

 Score = 26.2 bits (56), Expect = 8.4,   Method: Compositional matrix adjust.
 Identities = 19/72 (26%), Positives = 32/72 (44%)
 Frame = +3

Query: 54  SIEKFKSSSLSFTVFDMSGQGRYRNLWEHYYKDGQAIIFVIDSSDKLRMVVAKEELDTLL 113
           SI +F  S+   T+   S  G    LWE +  +G+ +    ++SDKL ++          
Sbjct: 129 SIFRFSGSTWDRTLKVGSPSG----LWEKWMNEGEHLSLNQENSDKLHLLKRA------- 275

Query: 114 NHPDIKHRRIPI 125
            H  +KH  +P 
Sbjct: 276 -HGSVKHGTVPF 308
>23882
          Length = 863

 Score = 26.2 bits (56), Expect = 8.9,   Method: Compositional matrix adjust.
 Identities = 18/48 (37%), Positives = 26/48 (54%), Gaps = 8/48 (16%)
 Frame = +2

Query: 47  IVPTIGF---SIEKFKSSSLSFTV-----FDMSGQGRYRNLWEHYYKD 86
            +P+I F   S  KF S S S+ +     F +S QG+Y+ LW H + D
Sbjct: 494 YLPSIMFLHNSYYKF-SFSKSYYIS*HYSFSLSYQGKYQPLWHHKFAD 634
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|27734154|ref|NP_775589.1| RAB8B, member RAS oncogene
family [Mus musculus]
         (207 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

08428                                                                 142   8e-35
34468                                                                 139   6e-34
33374                                                                 107   9e-30
33794                                                                 118   2e-27
34597                                                                 109   3e-27
26083                                                                 115   2e-26
07465                                                                 113   6e-26
33380                                                                 107   8e-26
05468                                                                 110   5e-25
32723                                                                 101   3e-22
14456                                                                 100   3e-22
17511                                                                 100   8e-22
01398                                                                  99   9e-22
07580                                                                  97   4e-21
30760                                                                  97   4e-21
13901                                                                  88   2e-18
19006                                                                  88   2e-18
11257                                                                  87   7e-18
01972                                                                  77   7e-18
13750                                                                  86   1e-17
12339                                                                  85   3e-17
11728                                                                  79   1e-15
35581                                                                  79   2e-15
00858                                                                  78   2e-15
27191                                                                  78   2e-15
13745                                                                  77   7e-15
19656                                                                  73   7e-14
26536                                                                  72   1e-13
01095                                                                  68   3e-12
34359                                                                  59   8e-12
09204                                                                  63   1e-10
19046                                                                  62   2e-10
24619                                                                  60   6e-10
14775                                                                  55   2e-08
09827                                                                  55   3e-08
08153                                                                  54   4e-08
29380                                                                  51   3e-07
31291                                                                  50   5e-07
18509                                                                  49   1e-06
00552                                                                  49   2e-06
25796                                                                  46   8e-06
14119                                                                  46   1e-05
10862                                                                  46   1e-05
33605                                                                  45   3e-05
12443                                                                  44   4e-05
10708                                                                  37   0.008
18184                                                                  32   0.24 
02923                                                                  30   0.53 
11299                                                                  29   1.1  
31593                                                                  27   3.9  
29444                                                                  27   4.5  
12784                                                                  27   7.1  
06048                                                                  27   8.4  
32321                                                                  27   8.5  
>08428
          Length = 1109

 Score =  142 bits (359), Expect = 8e-35,   Method: Compositional matrix adjust.
 Identities = 64/163 (39%), Positives = 102/163 (62%)
 Frame = -3

Query: 10   KLLLIGDSGVGKTCLLFRFSEDAFNTTFISTIGIDFKIRTIELDGKKIKLQIWDTAGQER 69
            K+ L+GDSGVGK+ ++ RF   ++  +  STIG  F  +++ +DG   + QIWDTAGQE+
Sbjct: 1065 KVCLLGDSGVGKSSIVLRFVTGSYRPSQESTIGASFMSKSLVVDGAGYRFQIWDTAGQEK 886

Query: 70   FRTITTAYYRGAMGIMLVYDITNEKSFDNIKNWIRNIEEHASSDVERMILGNKCDMNDKR 129
            FR +   YYRGA   ++VYD+T  ++F ++K+WI+ +      ++   I GNKCD+ + R
Sbjct: 885  FRALAPMYYRGAAAAVIVYDVTRPRTFKSVKSWIQELRSFGPPNIVLAIAGNKCDLEELR 706

Query: 130  QVSKERGEKLAIDYGIKFLETSAKSSTNVEEAFFTLARDIMTK 172
            +V ++  ++ A      F ETSA ++ NVEE F  LAR +  +
Sbjct: 705  EVVEKDAQEYASSISAIFGETSAMTAVNVEEMFTELARQLPPE 577
>34468
          Length = 1502

 Score =  139 bits (351), Expect = 6e-34,   Method: Compositional matrix adjust.
 Identities = 70/186 (37%), Positives = 115/186 (61%), Gaps = 5/186 (2%)
 Frame = +1

Query: 3   KTYDYLFKLLLIGDSGVGKTCLLFRFSEDAFNTTFISTIGIDFKIRTIELDGKKIKLQIW 62
           +T   +FK+++IGDS VGKTCL +RF    F     +TIG+DF+ ++I++D + +KLQ+W
Sbjct: 478 QTQRRIFKIIVIGDSNVGKTCLTYRFCLGKFPDKTEATIGVDFREKSIQVDSEHLKLQLW 657

Query: 63  DTAGQERFR-TITTAYYRGAMGIMLVYDITNEKSFDNIKNWIRNIEEH-ASSDVERMILG 120
           DTAGQERFR ++   YYR    ++ VYD+T   SF+N+  WI   + H  +  + R+++G
Sbjct: 658 DTAGQERFRKSMVQHYYRNVHAVVFVYDMTKMSSFENMPAWIEECDRHNLTKYIPRILVG 837

Query: 121 NKCDMNDKRQVSKERGEKLAIDYGIKFLETSAK---SSTNVEEAFFTLARDIMTKLNRKM 177
           NKCD+ ++  V+    +K A  + +   ETSAK    + +V+  F T+A  +  K ++ M
Sbjct: 838 NKCDVVERIAVNTNLAQKFADAHNMPLFETSAKDDEKANHVDAIFMTVAHKL--KXSKPM 1011

Query: 178 NDSNSS 183
             ++ S
Sbjct: 1012MPAHLS 1029
>33374
          Length = 489

 Score =  107 bits (268), Expect(2) = 9e-30,   Method: Compositional matrix adjust.
 Identities = 47/114 (41%), Positives = 73/114 (64%)
 Frame = +1

Query: 45  FKIRTIELDGKKIKLQIWDTAGQERFRTITTAYYRGAMGIMLVYDITNEKSFDNIKNWIR 104
           F  +T+ LD   +K +IWDTAGQER+ ++   YYRGA   ++VYDITN+ +F   K W++
Sbjct: 139 FLTQTVCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNQDTFGRAKTWVK 318

Query: 105 NIEEHASSDVERMILGNKCDMNDKRQVSKERGEKLAIDYGIKFLETSAKSSTNV 158
            ++  AS ++   + GNK D+ +KR V  E  +  A +  + F+ETSAK++ NV
Sbjct: 319 ELQRQASPNIVIALAGNKADLANKRMVEFEEAQAYAEENSLLFMETSAKTAMNV 480

 Score = 39.3 bits (90), Expect(2) = 9e-30,   Method: Compositional matrix adjust.
 Identities = 20/44 (45%), Positives = 28/44 (63%)
 Frame = +2

Query: 9  FKLLLIGDSGVGKTCLLFRFSEDAFNTTFISTIGIDFKIRTIEL 52
          FKL+L+G+S VGK+ L+ RF +  F+    STIG  F +R   L
Sbjct: 32 FKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAF*LRQFVL 163
>33794
          Length = 779

 Score =  118 bits (295), Expect = 2e-27,   Method: Compositional matrix adjust.
 Identities = 57/125 (45%), Positives = 82/125 (65%)
 Frame = -1

Query: 43  IDFKIRTIELDGKKIKLQIWDTAGQERFRTITTAYYRGAMGIMLVYDITNEKSFDNIKNW 102
           + +K  TI L+GK++KLQIWDT+GQ RF TI  +Y RGA GI+LVYDITN+ SFD I  W
Sbjct: 692 VAYKTTTILLEGKRVKLQIWDTSGQGRFCTIIRSYSRGAQGIILVYDITNKWSFDGIDRW 513

Query: 103 IRNIEEHASSDVERMILGNKCDMNDKRQVSKERGEKLAIDYGIKFLETSAKSSTNVEEAF 162
           ++ +EEHA   + ++++GN+  +  KRQV+ ++ E  A    +   E S     N+ E+F
Sbjct: 512 LKEVEEHAPG-IPKVLVGNRLHLAYKRQVAAKQAETYASRNNMSCFEISPLCDFNIRESF 336

Query: 163 FTLAR 167
             LAR
Sbjct: 335 CELAR 321
>34597
          Length = 773

 Score =  109 bits (272), Expect(2) = 3e-27,   Method: Compositional matrix adjust.
 Identities = 51/79 (64%), Positives = 64/79 (81%)
 Frame = -2

Query: 94  KSFDNIKNWIRNIEEHASSDVERMILGNKCDMNDKRQVSKERGEKLAIDYGIKFLETSAK 153
           KSF+NI  W+RNI+EHA+ DVE+MILGNKCDM DKR VSKERGE +A ++ I+F+ETSAK
Sbjct: 712 KSFENIVKWLRNIDEHANEDVEKMILGNKCDMTDKRVVSKERGEAIAREHSIRFMETSAK 533

Query: 154 SSTNVEEAFFTLARDIMTK 172
           S+ N+E AF  LA  I+ K
Sbjct: 532 SNINIERAFCELAEAILDK 476

 Score = 28.9 bits (63), Expect(2) = 3e-27,   Method: Compositional matrix adjust.
 Identities = 12/13 (92%), Positives = 13/13 (100%)
 Frame = -3

Query: 75  TAYYRGAMGIMLV 87
           T+YYRGAMGIMLV
Sbjct: 771 TSYYRGAMGIMLV 733
>26083
          Length = 432

 Score =  115 bits (287), Expect = 2e-26,   Method: Compositional matrix adjust.
 Identities = 54/114 (47%), Positives = 78/114 (68%)
 Frame = +1

Query: 9   FKLLLIGDSGVGKTCLLFRFSEDAFNTTFISTIGIDFKIRTIELDGKKIKLQIWDTAGQE 68
           FKL+ +G+  VGKT L+ RF  D+F+ T+ +TIGIDF  +T+ L+ + I+LQ+WDTAGQE
Sbjct: 79  FKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTIRLQLWDTAGQE 258

Query: 69  RFRTITTAYYRGAMGIMLVYDITNEKSFDNIKNWIRNIEEHASSDVERMILGNK 122
           RFR++  +Y R +   ++VYDITN  SF     WI ++     SDV  M++GNK
Sbjct: 259 RFRSLIPSYIRDSSVAVVVYDITNANSFHQTSKWIDDVRTERGSDVIIMLVGNK 420
>07465
          Length = 1103

 Score =  113 bits (282), Expect = 6e-26,   Method: Compositional matrix adjust.
 Identities = 61/172 (35%), Positives = 96/172 (55%)
 Frame = +3

Query: 22  TCLLFRFSEDAFNTTFISTIGIDFKIRTIELDGKKIKLQIWDTAGQERFRTITTAYYRGA 81
           + ++ R+ +  F   +  TIG+DF  R IE+ G+ ++L +WDTAGQE F  IT AYYRGA
Sbjct: 240 SSMIQRYCKGIFTKDYKKTIGVDFLERQIEVGGEDVRLMLWDTAGQEEFDAITKAYYRGA 419

Query: 82  MGIMLVYDITNEKSFDNIKNWIRNIEEHASSDVERMILGNKCDMNDKRQVSKERGEKLAI 141
              +L +   +  SF+ ++ W R +E+    ++  +I+ NK D+ D   V  E  E LA 
Sbjct: 420 QACVLAFSTVDRDSFEALETWKRKVEDEV-GEIGMVIVQNKIDLIDDAVVRPEEAENLAK 596

Query: 142 DYGIKFLETSAKSSTNVEEAFFTLARDIMTKLNRKMNDSNSSGAGGPVKITE 193
              ++F  TS K + NV+E F  LA   + +LN  M++ N +    P KI +
Sbjct: 597 KLRLRFYRTSVKENMNVDEVFRYLADKYLHQLNTGMDEVNLT----PQKIGQ 740
>33380
          Length = 282

 Score =  107 bits (267), Expect(2) = 8e-26,   Method: Compositional matrix adjust.
 Identities = 43/75 (57%), Positives = 64/75 (85%)
 Frame = +3

Query: 55  KKIKLQIWDTAGQERFRTITTAYYRGAMGIMLVYDITNEKSFDNIKNWIRNIEEHASSDV 114
           K++KLQIWDTAGQER+RTITTAYYRGAMG +L+YD+TNE+SF+ +++W   I+ ++  + 
Sbjct: 54  KRVKLQIWDTAGQERYRTITTAYYRGAMGFILMYDVTNEESFNAVQDWCTQIKTYSWDNA 233

Query: 115 ERMILGNKCDMNDKR 129
           + +++GNKCD+ D+R
Sbjct: 234 QVVLVGNKCDLEDER 278

 Score = 26.6 bits (57), Expect(2) = 8e-26,   Method: Compositional matrix adjust.
 Identities = 8/15 (53%), Positives = 14/15 (93%)
 Frame = +2

Query: 37 FISTIGIDFKIRTIE 51
          F+ST+GIDFK+ +++
Sbjct: 2  FVSTVGIDFKVNSLQ 46
>05468
          Length = 1558

 Score =  110 bits (274), Expect = 5e-25,   Method: Compositional matrix adjust.
 Identities = 64/184 (34%), Positives = 105/184 (57%), Gaps = 11/184 (5%)
 Frame = -3

Query: 6    DYLFKLLLIGDSGVGKTCLLFRFSEDAFNTTFISTIGIDFKIRTIELDGKK-IKLQIWDT 64
            ++L+K+L+IG+ G GKT ++ R+    F+  + +TIG+DF ++ +  D    I+LQ+WD 
Sbjct: 1547 EHLYKILVIGELGTGKTSIIKRYVHQFFSQHYRATIGVDFALKVLNWDADTLIRLQLWDI 1368

Query: 65   AGQERFRTITTAYYRGAMGIMLVYDITNEKSFDNIKNWIRNIEEHAS----SDVERMILG 120
            AGQERF  +T  YY+ A+G  +V+D+T   +FD +  W  +++        S V  ++L 
Sbjct: 1367 AGQERFGNMTRVYYKEAVGAFVVFDVTRASTFDAVTKWKNDLDSKVQLADGSPVPCVLLA 1188

Query: 121  NKCD------MNDKRQVSKERGEKLAIDYGIKFLETSAKSSTNVEEAFFTLARDIMTKLN 174
            NKCD      +N+  Q+ +   EK  I +     ETSAK + N++EA   L   I+ K +
Sbjct: 1187 NKCDQAKEGLVNNTSQMDEFCSEKGFIGW----YETSAKENINIDEAARFLVTRILEK-D 1023

Query: 175  RKMN 178
            R M 
Sbjct: 1022 RAMQ 1011
>32723
          Length = 384

 Score =  101 bits (251), Expect = 3e-22,   Method: Compositional matrix adjust.
 Identities = 49/126 (38%), Positives = 80/126 (63%), Gaps = 4/126 (3%)
 Frame = +2

Query: 67  QERFRTITTAYYRGAMGIMLVYDITNEKSFDNIKNWIRNIEEHASSDVERMILGNKCDMN 126
           QERFR+IT +YYR A  ++LVYD+ +++S++++  WI  IE +A + V   ++GNK D  
Sbjct: 2   QERFRSITQSYYRSANALILVYDVCSQQSYESLPQWIHEIELYAGTKVLAFLVGNKIDQT 181

Query: 127 DKRQVSKERGEKLAIDYGIKFLETSAKSSTNVEEAFFTLARDIMTKLNRKMN-DSNSSGA 185
           DKR++    G++ A  Y ++FLETSAK + NVE+ F T+A  +  +    +  ++ + G 
Sbjct: 182 DKREIPTHIGKEFAERYEMRFLETSAKEADNVEKLFSTIAYQLTAQAQGTLGAEA*TQGP 361

Query: 186 ---GGP 188
              GGP
Sbjct: 362 LSLGGP 379
>14456
          Length = 1867

 Score =  100 bits (250), Expect = 3e-22,   Method: Compositional matrix adjust.
 Identities = 53/156 (33%), Positives = 90/156 (57%), Gaps = 6/156 (3%)
 Frame = -1

Query: 18   GVGKTCLLFRFSEDAFNTTFISTIGIDFKIRTIELDGKKIKLQIWDTAGQERFRTITTAY 77
            GVGK+ L+ RF  + F+     TIG++F  + + +D +   +QIWDTAGQERF+++ T +
Sbjct: 1111 GVGKSSLMNRFVSNKFDAQSFHTIGVEFLNKDVVVDDETYTMQIWDTAGQERFKSLRTPF 932

Query: 78   YRGAMGIMLVYDITNEKSFDNIKNWIRNIEEHASSDVER------MILGNKCDMNDKRQV 131
            YRGA   +L + + + +SF N+  W +    +A  D++       ++LGNK D+  ++  
Sbjct: 931  YRGADCCLLTFSVDSMQSFRNLSMWRKEFLYYA--DIQDGVTFPFVVLGNKIDVEGRQVT 758

Query: 132  SKERGEKLAIDYGIKFLETSAKSSTNVEEAFFTLAR 167
            ++E       +    + ETSAK +TNVE+AF    +
Sbjct: 757  NEEARSWCTANSNAPYFETSAKDATNVEKAFLAAVQ 650
>17511
          Length = 483

 Score = 99.8 bits (247), Expect = 8e-22,   Method: Compositional matrix adjust.
 Identities = 50/129 (38%), Positives = 81/129 (62%), Gaps = 4/129 (3%)
 Frame = -3

Query: 1   MAKTYDYLFKLLLIGDSGVGKTCLLFRFSEDAFNTTFISTIGIDFKIRTIELDGKKIKLQ 60
           MA     L K++++GDSGVGKT L+ ++    F+  + +TIG DF  + + +D + + +Q
Sbjct: 388 MASRKKVLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQ 209

Query: 61  IWDTAGQERFRTITTAYYRGAMGIMLVYDITNEKSFDNIKNWIRNIEEHASS-DVER--- 116
           IWDTAGQERF+++  A+YRGA   +LV+D+T   +F ++ +W       AS  D E    
Sbjct: 208 IWDTAGQERFQSLGVAFYRGADCCVLVFDVTMPNTFRSLDSWRDEFLIQASPRDPENFPF 29

Query: 117 MILGNKCDM 125
           +++GNK D+
Sbjct: 28  VVIGNKIDL 2
>01398
          Length = 1421

 Score = 99.4 bits (246), Expect = 9e-22,   Method: Compositional matrix adjust.
 Identities = 48/113 (42%), Positives = 71/113 (62%), Gaps = 5/113 (4%)
 Frame = -2

Query: 67   QERFRTITTAYYRGAMGIMLVYDITNEKSFDNIKNWIRNIEEHASSDVER-----MILGN 121
            QERFR+IT +YYR ++G+++VYDIT   +F+N+K W     E A + +E      ++LG+
Sbjct: 1420 QERFRSITRSYYRNSVGVIIVYDITKRSTFENLKQWY----EEARNHIEPHKAIFLVLGH 1253

Query: 122  KCDMNDKRQVSKERGEKLAIDYGIKFLETSAKSSTNVEEAFFTLARDIMTKLN 174
            K D  D RQV+   G + A  +G+KF ETSAKS  N+E+ F  +A+D    L 
Sbjct: 1252 KSDREDARQVTAREGRRFAEMHGLKFFETSAKSGHNIEDVFAQIAKDTYQHLQ 1094
>07580
          Length = 921

 Score = 97.4 bits (241), Expect = 4e-21,   Method: Compositional matrix adjust.
 Identities = 53/155 (34%), Positives = 86/155 (55%), Gaps = 1/155 (0%)
 Frame = +3

Query: 19  VGKTCLLFRFSEDAFNTTFISTIGIDFKIRTIELDGKKIKLQIWDTAGQERFRTITTAYY 78
           + K   L+   +  F   +  TI   ++ + +E+DG++  L+I DTAG E+F  +   Y 
Sbjct: 93  LAKVL*LYSLCKGIFVEKYDPTIEDSYR-KQVEVDGQQCMLEILDTAGTEQFTAMRDLYM 269

Query: 79  RGAMGIMLVYDITNEKSFDNIKNWIRNI-EEHASSDVERMILGNKCDMNDKRQVSKERGE 137
           +   G +L Y IT + +F++++     I     + DV  +++GNKCD+ D+R V K++G+
Sbjct: 270 KNGQGFLLAYSITAQSTFNDLQELREQILRVKDTDDVPMLLVGNKCDLEDERVVGKDQGQ 449

Query: 138 KLAIDYGIKFLETSAKSSTNVEEAFFTLARDIMTK 172
            LA  +   FLETSAK+  NV E F  L R I  K
Sbjct: 450 GLARSFSCAFLETSAKARINVNEIFMDLVRQINKK 554
>30760
          Length = 596

 Score = 97.4 bits (241), Expect = 4e-21,   Method: Compositional matrix adjust.
 Identities = 49/163 (30%), Positives = 92/163 (56%), Gaps = 5/163 (3%)
 Frame = -1

Query: 10  KLLLIGDSGVGKT--CLLFRFSEDAFNTTFISTIGIDFKIRTIELDGKK--IKLQIWDTA 65
           K ++ GDSGVGK+  C +F      F   +  T G++  ++ + +   +  ++L ++D+A
Sbjct: 524 KCIVTGDSGVGKSSICQVFHSDSAHFPKNYSMTTGVEVLVKLVNIPDSRDQVELYLFDSA 345

Query: 66  GQERFRTITTAYYRGAMGIMLVYDITNEKSFDNIKNWIRNIEEHASSDV-ERMILGNKCD 124
           G+E F    T ++     +M+VYD+T+E SF     W+  +     + V   +++ NK D
Sbjct: 344 GKEIFSENVTKFWDQPSVVMVVYDVTDETSFSGCVRWLERVRAAKPNTVIPGVLVANKTD 165

Query: 125 MNDKRQVSKERGEKLAIDYGIKFLETSAKSSTNVEEAFFTLAR 167
           ++++R+VS++ G+ LA  +G+++ E SAK   N +  FF LA 
Sbjct: 164 LDERRRVSRKEGKDLAQSHGLEYFECSAKEMQNTDTPFFCLAH 36
>13901
          Length = 962

 Score = 88.2 bits (217), Expect = 2e-18,   Method: Compositional matrix adjust.
 Identities = 40/96 (41%), Positives = 62/96 (64%), Gaps = 1/96 (1%)
 Frame = -3

Query: 8   LFKLLLIGDSGVGKTCLLFRFSEDAFNTTFISTIGIDFKIRTIELDGK-KIKLQIWDTAG 66
           LFK+++IGD  VGKT  + R+  D+F   +  TIG+DF ++ I    K  IKLQ+WD AG
Sbjct: 288 LFKVIIIGDPTVGKTSFVQRYVNDSFRRDYKMTIGVDFALKVIRWSDKCNIKLQLWDIAG 109

Query: 67  QERFRTITTAYYRGAMGIMLVYDITNEKSFDNIKNW 102
           QERF ++T  YY+ A   ++++D+T + ++ N   W
Sbjct: 108 QERFTSMTRVYYKDAHACIVMFDLTQKNTYQNAIRW 1
>19006
          Length = 568

 Score = 88.2 bits (217), Expect = 2e-18,   Method: Compositional matrix adjust.
 Identities = 46/138 (33%), Positives = 80/138 (57%), Gaps = 5/138 (3%)
 Frame = -2

Query: 10  KLLLIGDSGVGKTCLLFRFSEDAFNTTFISTIGIDFKIRTIELDGKKIKLQIWDTAGQER 69
           KL+++GD   GKTCLL  FS+D F   ++ T+  ++ +  IE+D K+++L +WDTAGQE 
Sbjct: 432 KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENY-VADIEVDSKQVELALWDTAGQED 256

Query: 70  FRTITTAYYRGAMGIMLVYDITNEKSFDNI-KNWIRNIEEHASSDVERMILGNKCDM--- 125
           +  +    Y     I++ + I +  S +NI + W   +  H   +V  +++GNK D+   
Sbjct: 255 YDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEV-RHFCPNVPIILVGNKKDLRND 79

Query: 126 -NDKRQVSKERGEKLAID 142
            N KR++ K + E + +D
Sbjct: 78  ENTKRELMKMKQEPVRLD 25
>11257
          Length = 1102

 Score = 86.7 bits (213), Expect = 7e-18,   Method: Compositional matrix adjust.
 Identities = 44/125 (35%), Positives = 74/125 (59%), Gaps = 5/125 (4%)
 Frame = -2

Query: 48   RTIELDGKKIKLQIWDTAGQERFRTITTAYYRGAMGIMLVYDITNEKSFDNIKNWIRNIE 107
            + + +DG+   +QIWDTAGQER++++ T +YRG    +L + + N KS  ++ +W     
Sbjct: 1053 KDVVVDGETFTMQIWDTAGQERYKSLRTPFYRGTDCCLLTFSVDNLKSLQSLSDWYDEFV 874

Query: 108  EHA----SSDVERMILGNKCDMNDKRQVSKERGEKLAIDYG-IKFLETSAKSSTNVEEAF 162
             +A    S+    +I+GNK D+ ++R+VS E        +G + + ETSAK S NV++AF
Sbjct: 873  NYADIQDSASFPFVIIGNKADI-EEREVSSEDAYNWCRTHGNLPYFETSAKDSLNVQQAF 697

Query: 163  FTLAR 167
              + R
Sbjct: 696  LAVVR 682
>01972
          Length = 2359

 Score = 76.6 bits (187), Expect(2) = 7e-18,   Method: Compositional matrix adjust.
 Identities = 37/138 (26%), Positives = 74/138 (53%)
 Frame = +3

Query: 37  FISTIGIDFKIRTIELDGKKIKLQIWDTAGQERFRTITTAYYRGAMGIMLVYDITNEKSF 96
           +++T+G++           K+K  +WDTAGQE+F  +   YY      ++++D+T+  ++
Sbjct: 387 YVATLGVEVHPLLFHTSRGKLKFNVWDTAGQEKFGGLRDGYYIQGQCAVIMFDVTSRVTY 566

Query: 97  DNIKNWIRNIEEHASSDVERMILGNKCDMNDKRQVSKERGEKLAIDYGIKFLETSAKSST 156
            N+ NW R++      ++  ++ GNK D+ D++   K +         +++ + SAKS+ 
Sbjct: 567 KNVPNWHRDLVR-VCENIPIVLCGNKVDIKDRK--VKAKAIVFHRKKNLQYYDISAKSNY 737

Query: 157 NVEEAFFTLARDIMTKLN 174
           N E+ F  LAR ++   N
Sbjct: 738 NFEKPFLWLARKLVGDPN 791

 Score = 30.4 bits (67), Expect(2) = 7e-18,   Method: Compositional matrix adjust.
 Identities = 13/31 (41%), Positives = 17/31 (54%)
 Frame = +1

Query: 9   FKLLLIGDSGVGKTCLLFRFSEDAFNTTFIS 39
           FKL+L+GD GVGKT  + R     F    + 
Sbjct: 304 FKLVLVGDGGVGKTTFVKRHVTGEFEKNMLP 396
>13750
          Length = 503

 Score = 85.5 bits (210), Expect = 1e-17,   Method: Compositional matrix adjust.
 Identities = 52/162 (32%), Positives = 86/162 (53%), Gaps = 4/162 (2%)
 Frame = -2

Query: 21  KTCLLFRFSEDAFNTTFISTIGI---DF-KIRTIELDGKKIKLQIWDTAGQERFRTITTA 76
           KTCLL R+ +  F    + TI +   +F + RT   D   ++  +WDT G E +R++  +
Sbjct: 502 KTCLLRRYQKGFFMDRTMPTIAVLCSEFNESRT---DPLNVRYTLWDTGGAETYRSLWVS 332

Query: 77  YYRGAMGIMLVYDITNEKSFDNIKNWIRNIEEHASSDVERMILGNKCDMNDKRQVSKERG 136
           ++RGA   +LVYD+T E SF       R        + + + +G+K D+ + R +S ERG
Sbjct: 331 HFRGAQVALLVYDVTCEWSFLTATTVWRKALMKNIPEAQVIFVGSKTDLEENRVISTERG 152

Query: 137 EKLAIDYGIKFLETSAKSSTNVEEAFFTLARDIMTKLNRKMN 178
           +  A   G  F ETS+ +  NV+  F+ +A  I+ +L R  +
Sbjct: 151 QAFATQCGYTFFETSSVTGKNVDAVFWEIAF-ILARLQRSAH 29
>12339
          Length = 578

 Score = 84.7 bits (208), Expect = 3e-17,   Method: Compositional matrix adjust.
 Identities = 46/111 (41%), Positives = 72/111 (64%), Gaps = 5/111 (4%)
 Frame = -2

Query: 67  QERFRTITTAYYRGAMGIMLVYDITNEKSFDNIKNWIRNIEEHASS-DVER---MILGNK 122
           QERF+++  A+YRGA   +LVYD+T  K+FD++ +W R     AS  D E    +++GNK
Sbjct: 577 QERFQSLGVAFYRGADCCILVYDVTEXKTFDSLDSWQREFLNQASPRDPEHFPFVVIGNK 398

Query: 123 CDMNDKRQVSKERGEK-LAIDYGIKFLETSAKSSTNVEEAFFTLARDIMTK 172
            D+ D R V+ +RG+   +   GI + ETSAK + NVE+AF T+A++ + +
Sbjct: 397 IDL-DNRVVTAKRGQGWCSTKGGIPYFETSAKEAINVEQAFQTVAKNALAQ 248
>11728
          Length = 635

 Score = 79.0 bits (193), Expect = 1e-15,   Method: Compositional matrix adjust.
 Identities = 42/134 (31%), Positives = 71/134 (52%), Gaps = 2/134 (1%)
 Frame = -1

Query: 9   FKLLLIGDSGVGKTCLLFRFSEDAFNTTFISTIGIDFKIRTIELDGKKIKLQIWDTAGQE 68
            K +++GD  VGKTCLL  ++ +AF   +I T+  D     + +D K I L +WDTAGQE
Sbjct: 488 IKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTV-FDNYSANVMVDSKPINLGLWDTAGQE 312

Query: 69  RFRTITTAYYRGAMGIMLVYDITNEKSFDNIK-NWIRNIEEHASSDVERMILGNKCDM-N 126
            +  +    Y      ++ + + +  SF+N+K  W   +  H   +   +++G K D+  
Sbjct: 311 DYDRLRPLSYPQTDVFLICFSLISPASFENVKAKWYPEVSHHC-PNTPIILVGTKLDLRE 135

Query: 127 DKRQVSKERGEKLA 140
           DK  + K + +KLA
Sbjct: 134 DKETIEKLKEKKLA 93
>35581
          Length = 364

 Score = 78.6 bits (192), Expect = 2e-15,   Method: Compositional matrix adjust.
 Identities = 35/82 (42%), Positives = 56/82 (68%), Gaps = 1/82 (1%)
 Frame = +2

Query: 9   FKLLLIGDSGVGKTCLLFRFSEDAFNTTFISTIGIDFKIRTIEL-DGKKIKLQIWDTAGQ 67
           FK +L+GD+GVGKTCLL R + D F  + ++++     + T+ L  G    + +WDTAGQ
Sbjct: 47  FKCVLLGDAGVGKTCLLNRLATDKFLDSPLTSLTTASLLTTVTLTSGVMASVDLWDTAGQ 226

Query: 68  ERFRTITTAYYRGAMGIMLVYD 89
           ER+R++T++YYR    +++VYD
Sbjct: 227 ERYRSLTSSYYRDTKAVLIVYD 292
>00858
          Length = 1658

 Score = 78.2 bits (191), Expect = 2e-15,   Method: Compositional matrix adjust.
 Identities = 55/162 (33%), Positives = 90/162 (55%), Gaps = 1/162 (0%)
 Frame = -2

Query: 9    FKLLLIGDSGVGKTCLLFRFSEDAFNTTFISTIGIDFKIRTIELDGKKIKLQIWDTAGQE 68
            +KL+++G  GVGK+ L  +  ++ F   +  T   D   + + +DG+   L I DTAGQE
Sbjct: 1588 YKLVVVGAGGVGKSALTIQLXQNHFVEEYDPTXE-DSXRKQVVIDGETCLLDILDTAGQE 1412

Query: 69   RFRTITTAYYRGAMGIMLVYDITNEKSFDNIKNWIRNIEEHASSDVERMIL-GNKCDMND 127
                +     R   G + V+ + N KSF++I  +   I+    +D   M+L GNK D+  
Sbjct: 1411 EXSAMRDQCMRTGEGFLCVFAVXNLKSFEDINQYREQIKRVKDADEVPMVLVGNKVDLP- 1235

Query: 128  KRQVSKERGEKLAIDYGIKFLETSAKSSTNVEEAFFTLARDI 169
             R V + +G+ +A  Y I ++ETSAK+   V++AF+TL R+I
Sbjct: 1234 IRNVEQRQGKHMAELYHIPYVETSAKTRQGVDDAFYTLVREI 1109
>27191
          Length = 443

 Score = 78.2 bits (191), Expect = 2e-15,   Method: Compositional matrix adjust.
 Identities = 33/117 (28%), Positives = 64/117 (54%)
 Frame = +1

Query: 21  KTCLLFRFSEDAFNTTFISTIGIDFKIRTIELDGKKIKLQIWDTAGQERFRTITTAYYRG 80
           KTCL+  F E  FN  +  T+G+D+  +   ++G  +++ +WD +G   +  +    Y G
Sbjct: 1   KTCLIKHFCESKFNQGYQPTVGVDYGFKIQTVNGVDMRVHMWDLSGSNEYLDVRNELYTG 180

Query: 81  AMGIMLVYDITNEKSFDNIKNWIRNIEEHASSDVERMILGNKCDMNDKRQVSKERGE 137
           +  I +V+D++N  SF+ + +W+R I   A+     +I+GN+   N   Q  +++ E
Sbjct: 181 SDAIFIVFDVSNTPSFEALDSWLREINRFATGSPLNVIVGNRVI*NRSAQCRQQKQE 351
>13745
          Length = 1045

 Score = 76.6 bits (187), Expect = 7e-15,   Method: Compositional matrix adjust.
 Identities = 46/111 (41%), Positives = 65/111 (58%), Gaps = 5/111 (4%)
 Frame = +2

Query: 67  QERFRTITTAYYRGAMGIMLVYDITNEKSFDNIKNWIRNIEEHASS-DVER---MILGNK 122
           QERF+++  A+YRGA   +LVYD+T   SF N+ +W       AS  D E    ++LGNK
Sbjct: 2   QERFQSLGVAFYRGADCCVLVYDVTAPNSFKNLDSWRDEFLIQASPRDPEHFPFVVLGNK 181

Query: 123 CDMNDKRQVSKERGEKLAIDYG-IKFLETSAKSSTNVEEAFFTLARDIMTK 172
            D+ D RQVS  R ++       I + ETSAK   NVE AF T+A++ + +
Sbjct: 182 VDL-DNRQVSTRRAQQWCQSKNDIPYYETSAKEGINVEMAFQTIAKNALEQ 331
>19656
          Length = 428

 Score = 73.2 bits (178), Expect = 7e-14,   Method: Compositional matrix adjust.
 Identities = 33/103 (32%), Positives = 55/103 (53%), Gaps = 1/103 (0%)
 Frame = +3

Query: 10  KLLLIGDSGVGKTCLLFRFSEDAFNTTFISTIGIDFKIRTIELDGKKIKLQIWDTAGQER 69
           K +++GD  VGKTCLL  ++ +AF   +I T+  D     + +DG+ + L +WDTAGQE 
Sbjct: 117 KCVVVGDGAVGKTCLLISYTTNAFPGEYIPTV-FDNYSANVMVDGRPVNLGLWDTAGQED 293

Query: 70  FRTITTAYYRGAMGIMLVYDITNEKSFDNIK-NWIRNIEEHAS 111
           +  +    Y      +L + + +  SF+NI+  W   +  H  
Sbjct: 294 YDRLRPLSYPQTDVFLLCFSVASPASFENIRAKWYPEVNHHCP 422
>26536
          Length = 829

 Score = 72.4 bits (176), Expect = 1e-13,   Method: Compositional matrix adjust.
 Identities = 37/118 (31%), Positives = 64/118 (54%), Gaps = 3/118 (2%)
 Frame = +2

Query: 55  KKIKLQIWDTAGQERFRTITTAYYRGAMGIMLVYDITNEKSF---DNIKNWIRNIEEHAS 111
           +++     DTAGQE + ++   Y R   G ++VY +T+  SF   + +  W+   ++  S
Sbjct: 122 RRVSWTFLDTAGQEEYSSMREHYTRSGDGFIVVYSVTDVTSFQEAEAVFRWLTRFQDETS 301

Query: 112 SDVERMILGNKCDMNDKRQVSKERGEKLAIDYGIKFLETSAKSSTNVEEAFFTLARDI 169
             +  ++ GNK D+   R+V+ E G K+A   G+ + ETSAK+  NV + +  L R I
Sbjct: 302 --IHAVLCGNKTDLTSDRKVTPEEGRKMADRLGMLYFETSAKTGDNVSQVYHGLLRSI 469
>01095
          Length = 1745

 Score = 67.8 bits (164), Expect = 3e-12,   Method: Compositional matrix adjust.
 Identities = 30/84 (35%), Positives = 52/84 (61%)
 Frame = -1

Query: 86   LVYDITNEKSFDNIKNWIRNIEEHASSDVERMILGNKCDMNDKRQVSKERGEKLAIDYGI 145
            +VYDITN+ +F   K W++ ++  AS ++   + GNK D+ +KR V  E  +  A +  +
Sbjct: 1745 VVYDITNQDTFGRAKTWVKELQRQASPNIVIALAGNKADLANKRMVEFEEAQAYAEENSL 1566

Query: 146  KFLETSAKSSTNVEEAFFTLARDI 169
             F+ETSAK++ NV + F  +A+ +
Sbjct: 1565 LFMETSAKTAMNVNDIFLAIAKKL 1494
>34359
          Length = 1042

 Score = 58.9 bits (141), Expect(2) = 8e-12,   Method: Compositional matrix adjust.
 Identities = 24/97 (24%), Positives = 54/97 (55%)
 Frame = +3

Query: 37  FISTIGIDFKIRTIELDGKKIKLQIWDTAGQERFRTITTAYYRGAMGIMLVYDITNEKSF 96
           +++T+G++            ++  +WDTAGQE+F  +   YY      ++++D+T+  ++
Sbjct: 135 YVATLGVEVHPLQFNTSRGLLRFNVWDTAGQEKFGGLRDGYYIQGTCAIIMFDVTSRVTY 314

Query: 97  DNIKNWIRNIEEHASSDVERMILGNKCDMNDKRQVSK 133
            N+ NW R++      ++  ++ GNK D+ D++  +K
Sbjct: 315 KNVPNWHRDLVR-VCENIPIVLCGNKVDIKDRKVKAK 422

 Score = 27.3 bits (59), Expect(2) = 8e-12,   Method: Compositional matrix adjust.
 Identities = 12/38 (31%), Positives = 23/38 (60%)
 Frame = +2

Query: 137 EKLAIDYGIKFLETSAKSSTNVEEAFFTLARDIMTKLN 174
            +L+ +  +++ + SAKS+ N E+ F  LAR ++   N
Sbjct: 425 HRLSQEKNLQYYDISAKSNYNFEKPFLWLARKLVGDPN 538
>09204
          Length = 1051

 Score = 62.8 bits (151), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 34/106 (32%), Positives = 58/106 (54%), Gaps = 4/106 (3%)
 Frame = -3

Query: 69   RFRTITTAYYRGAMGIMLVYDITNEKSFDNIKNWIRNIEEHASSDVERMILGNKCDM--- 125
            R+  ++  YYRGA   +L +D+T++ SFD I+ WI  + +H   + +  I G K D+   
Sbjct: 1049 RYEAMSRIYYRGAKAAILCFDLTDKSSFDRIRFWIGELRQH-EEECKLYICGTKFDLVHD 873

Query: 126  -NDKRQVSKERGEKLAIDYGIKFLETSAKSSTNVEEAFFTLARDIM 170
              ++R V +   + LA D   +  ETS+ +  N+E+ F  +A D M
Sbjct: 872  DPERRAVPRSVAKALADDCMAEIYETSSMTGDNIEKLFTKIAEDYM 735
>19046
          Length = 445

 Score = 62.0 bits (149), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 39/105 (37%), Positives = 57/105 (54%), Gaps = 2/105 (1%)
 Frame = -2

Query: 67  QERFRTITTAYYRGAMGIMLVYDITNEKSFDNIKNWIRNIEEHASSDVERMIL-GNKCDM 125
           QE F  +   Y R   G +LV+ +T+ +SF+N+ N+   I      D   MIL  NK D+
Sbjct: 444 QEEFSAMREQYMRKGDGFLLVFSVTDFRSFENMANFHTQILRVKDRDSYPMILCANKVDL 265

Query: 126 NDKRQVSKERGEKLAIDYGIKFLETSAKSST-NVEEAFFTLARDI 169
             +R+VS+E+   LA    I ++ETSAK    NV+ AF  + R I
Sbjct: 264 VHQRKVSEEQVRDLATRLRIPYIETSAKDPPLNVDLAFHQVVRVI 130
>24619
          Length = 509

 Score = 60.1 bits (144), Expect = 6e-10,   Method: Compositional matrix adjust.
 Identities = 38/105 (36%), Positives = 56/105 (53%), Gaps = 2/105 (1%)
 Frame = -2

Query: 67  QERFRTITTAYYRGAMGIMLVYDITNEKSFDNIKNWIRNIEEHASSDVERMIL-GNKCDM 125
           QE F  +   Y R   G +LV+ + + +SF+N+ N+   I      D   MIL  NK D+
Sbjct: 508 QEEFSAMREQYMRKGDGFLLVFSVIDYQSFENMVNFHTQILRVKDRDTYPMILCANKVDL 329

Query: 126 NDKRQVSKERGEKLAIDYGIKFLETSAKSST-NVEEAFFTLARDI 169
             +R+VS+E+   LA    I ++ETSAK    NV+ AF  + R I
Sbjct: 328 VHQRKVSEEQVRDLATRLRIPYIETSAKDPPLNVDLAFHQVVRVI 194
>14775
          Length = 380

 Score = 55.1 bits (131), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 43/162 (26%), Positives = 69/162 (42%), Gaps = 4/162 (2%)
 Frame = -2

Query: 21  KTCLLFRFSEDAFNTTFISTIGI---DF-KIRTIELDGKKIKLQIWDTAGQERFRTITTA 76
           KTCLL R+ +  F    + TI +   +F + RT   D   ++  +WDT G E +R++  +
Sbjct: 379 KTCLLRRYQKGFFMDRTMPTIAVLCSEFNESRT---DPLNVRYTLWDTGGAETYRSLWVS 209

Query: 77  YYRGAMGIMLVYDITNEKSFDNIKNWIRNIEEHASSDVERMILGNKCDMNDKRQVSKERG 136
           ++RGA   +LVYD+T                                          ERG
Sbjct: 208 HFRGAQVALLVYDVTC-----------------------------------------ERG 152

Query: 137 EKLAIDYGIKFLETSAKSSTNVEEAFFTLARDIMTKLNRKMN 178
           +  A   G  F ETS+ +  NV+  F+ +A  I+ +L R  +
Sbjct: 151 QAFATQCGYTFFETSSVTGKNVDAVFWEIAF-ILARLQRSAH 29
>09827
          Length = 1201

 Score = 54.7 bits (130), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 37/138 (26%), Positives = 68/138 (49%), Gaps = 1/138 (0%)
 Frame = -3

Query: 10   KLLLIGDSGVGKTCLLFRFSEDAFNTTFISTIGIDFKIRTIELDGKKIKLQIWDTAGQER 69
            ++L++G    GKT +L++       TT I TIG  F + T+E   K I   +WD  GQ++
Sbjct: 1109 RILMVGLDAAGKTTILYKLKLGEIVTT-IPTIG--FNVETVEY--KNISFTVWDVGGQDK 945

Query: 70   FRTITTAYYRGAMGIMLVYDITNEKSFDNIKNWI-RNIEEHASSDVERMILGNKCDMNDK 128
             R +   Y++   G++ V D  +++     +  + R + E    D   ++  NK D+   
Sbjct: 944  IRPLWRHYFQNTQGLIFVVDSNDKERVQEAREELTRMLNEDELRDAVLLVFANKQDL-PH 768

Query: 129  RQVSKERGEKLAIDYGIK 146
               + E  EKL + +G++
Sbjct: 767  AMATAEITEKLGL-HGLR 717
>08153
          Length = 1703

 Score = 53.9 bits (128), Expect = 4e-08,   Method: Compositional matrix adjust.
 Identities = 34/125 (27%), Positives = 61/125 (48%), Gaps = 1/125 (0%)
 Frame = +1

Query: 10  KLLLIGDSGVGKTCLLFRFSEDAFNTTFISTIGIDFKIRTIELDGKKIKLQIWDTAGQER 69
           ++L++G    GKT +L++       TT I TIG  F + T+E   K I   +WD  GQ++
Sbjct: 88  RILMVGLDAAGKTTILYKLKLGEIVTT-IPTIG--FNVETVEY--KNISFTVWDVGGQDK 252

Query: 70  FRTITTAYYRGAMGIMLVYDITNEKSFDNIKNWI-RNIEEHASSDVERMILGNKCDMNDK 128
            R +   Y++   G++ V D  + +  +  K  + R + E    D   ++  NK D+ + 
Sbjct: 253 IRPLWRHYFQNTQGLIFVVDSNDRERINEAKEELARMLNEDDLRDAIILVFANKQDLPNA 432

Query: 129 RQVSK 133
              S+
Sbjct: 433 YSASE 447
>29380
          Length = 853

 Score = 51.2 bits (121), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 28/93 (30%), Positives = 47/93 (50%), Gaps = 1/93 (1%)
 Frame = -2

Query: 81  AMGIMLVYDITNEKSFDNIKNWIRNIEEHASSDVERMILGNKCDM-NDKRQVSKERGEKL 139
           A   ++VYD+    +F     W++ + +  +  V  ++ GNK D+    R VS E  +  
Sbjct: 852 ASAAIIVYDVNIADTFSRALAWVKELRQQNTESVLIILAGNKVDLATQHRAVSFEDAQSF 673

Query: 140 AIDYGIKFLETSAKSSTNVEEAFFTLARDIMTK 172
           A + G+ F E SAK+   V E F TLA  ++ +
Sbjct: 672 ARENGLLFAEVSAKTGMAVNEIFMTLANQLIQQ 574
>31291
          Length = 446

 Score = 50.4 bits (119), Expect = 5e-07,   Method: Compositional matrix adjust.
 Identities = 35/118 (29%), Positives = 54/118 (45%), Gaps = 14/118 (11%)
 Frame = -1

Query: 59  LQIWDTAGQERFRTITTAYYRGAMGIMLVYDITNEKSFDNIK-NWIRNIEEHASSDVERM 117
           LQ+WDTAGQE +  +    Y      ML + + +E S  N+K  W   I  H    V  +
Sbjct: 446 LQLWDTAGQEDYDRLRPLAYPNTDVFMLXFSLMSEASMKNVKVKWYPEIRHH-DPHVPIV 270

Query: 118 ILGNKCDMNDKRQ------------VSKERGEKLAIDYGIK-FLETSAKSSTNVEEAF 162
           ++G K D+   ++            VS  +G  LA     K + E S+K+  N++ AF
Sbjct: 269 LVGTKLDLRQDKEAVRKLRSSRQDPVSSNQGNDLAKAIKAKRYFECSSKTQENLKTAF 96
>18509
          Length = 625

 Score = 49.3 bits (116), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 25/66 (37%), Positives = 42/66 (63%)
 Frame = -3

Query: 111 SSDVERMILGNKCDMNDKRQVSKERGEKLAIDYGIKFLETSAKSSTNVEEAFFTLARDIM 170
           + +V  +++GNK D+   R V + +G+ +A  Y I ++ETSAK+   V++AF+TL R+I 
Sbjct: 536 ADEVPMVLVGNKVDL-PIRNVEQRQGKHMAELYHIPYVETSAKTRQGVDDAFYTLVREIR 360

Query: 171 TKLNRK 176
               RK
Sbjct: 359 KYKERK 342
>00552
          Length = 455

 Score = 48.5 bits (114), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 18/42 (42%), Positives = 29/42 (69%)
 Frame = -3

Query: 61  IWDTAGQERFRTITTAYYRGAMGIMLVYDITNEKSFDNIKNW 102
           IWDTAGQER++++ T +YRG    +L + + N KS  ++ +W
Sbjct: 147 IWDTAGQERYKSLRTPFYRGTDCCLLTFSVDNLKSLQSLSDW 22

 Score = 45.8 bits (107), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 20/53 (37%), Positives = 34/53 (64%)
 Frame = -1

Query: 8   LFKLLLIGDSGVGKTCLLFRFSEDAFNTTFISTIGIDFKIRTIELDGKKIKLQ 60
           L K++L+GD GVGK+ L+ RF  + F+     TIG++F  + + +DG+   +Q
Sbjct: 446 LLKVVLLGDGGVGKSSLMNRFVSNKFDAQSFHTIGVEFLTKDVVVDGETFTMQ 288
>25796
          Length = 422

 Score = 46.2 bits (108), Expect = 8e-06,   Method: Compositional matrix adjust.
 Identities = 18/28 (64%), Positives = 23/28 (82%)
 Frame = -1

Query: 1  MAKTYDYLFKLLLIGDSGVGKTCLLFRF 28
          M++TYDYLFK L+IG +G GK+CLL  F
Sbjct: 89 MSETYDYLFKFLIIGSAGSGKSCLLHHF 6
>14119
          Length = 602

 Score = 45.8 bits (107), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 29/100 (29%), Positives = 49/100 (49%), Gaps = 1/100 (1%)
 Frame = +1

Query: 95  SFDNIKNWIRNIEEHASSDVERMILGNKCDM-NDKRQVSKERGEKLAIDYGIKFLETSAK 153
           +F+    W++ + +  +  V  ++ GNK D+ ++ R VS +     A D G+ F E SAK
Sbjct: 1   TFNRALAWVKELRQQNAGSVLIVLAGNKADLASEHRAVSADDARTFAEDNGLIFAEVSAK 180

Query: 154 SSTNVEEAFFTLARDIMTKLNRKMNDSNSSGAGGPVKITE 193
           +   V E F T+A     KL R+  +     +G  V + E
Sbjct: 181 TGMAVSEVFMTIAH----KLVRRAEEGGGVWSGVQVYLFE 288
>10862
          Length = 2896

 Score = 45.8 bits (107), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 31/127 (24%), Positives = 53/127 (41%), Gaps = 1/127 (0%)
 Frame = -3

Query: 16   DSGVGKTCLLFRFSEDAFNTTFISTIGIDFKIRTIELDGKKIKLQIWDTAGQERFRTITT 75
            D  VG  C    +S     T  +     + +I+      ++ +  +WD  GQ++ R +  
Sbjct: 2609 DPHVGA*CCRENYSSIQNETRTVCDXNTNSRIQCRNCQLQECQFNVWDVGGQDKIRPLWR 2430

Query: 76   AYYRGAMGIMLVYDITNEKSFDNIKNWI-RNIEEHASSDVERMILGNKCDMNDKRQVSKE 134
             YY G  G++ V D  +    D  +  + R I +    D   +I  NK D+ D  +   E
Sbjct: 2429 HYYTGTQGLIFVVDCADRDRIDEARQELHRIINDREMRDAIILIFANKQDLPDAMK-PHE 2253

Query: 135  RGEKLAI 141
              EKL +
Sbjct: 2252 IQEKLGL 2232
>33605
          Length = 888

 Score = 44.7 bits (104), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 27/80 (33%), Positives = 44/80 (55%)
 Frame = +1

Query: 10  KLLLIGDSGVGKTCLLFRFSEDAFNTTFISTIGIDFKIRTIELDGKKIKLQIWDTAGQER 69
           +LL++G    GKT +L +F+ +  +T    T+G  F I+T+E  G   KL +WD  GQ+ 
Sbjct: 502 RLLMLGLDNAGKTTILKKFNGEDIDT-ISPTLG--FNIKTLEHRG--FKLNVWDVGGQQS 666

Query: 70  FRTITTAYYRGAMGIMLVYD 89
            R+    Y+    G++ V D
Sbjct: 667 LRSYWRNYFESTDGLVWVVD 726
>12443
          Length = 837

 Score = 43.9 bits (102), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 36/137 (26%), Positives = 67/137 (48%), Gaps = 9/137 (6%)
 Frame = -3

Query: 9   FKLLLIGDSGVGKTCLLFRFSEDAFNTTFISTIGID----FKIRTIELDGKKI--KLQIW 62
           +K++L+G +GVGKT  + + + +    T   T G+     +    I+  GK +  ++Q++
Sbjct: 580 YKVMLVGKTGVGKTSTVAKLTGNDIPLTHNETPGLQTSHLYWPGKIKHLGKTVLFQIQLF 401

Query: 63  DTAGQ---ERFRTITTAYYRGAMGIMLVYDITNEKSFDNIKNWIRNIEEHASSDVERMIL 119
           D AG+   +R+  I  A   G  GIM ++   ++ SFD I   +          + ++ L
Sbjct: 400 D-AGETALKRYDHILPACQDGVDGIMFLFSFVDKGSFDEIPQLLTRFTT-LEDGICKIAL 227

Query: 120 GNKCDMNDKRQVSKERG 136
           G K     K  ++K+RG
Sbjct: 226 GTKYPFPHKGIINKDRG 176
>10708
          Length = 2775

 Score = 36.6 bits (83), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 14/46 (30%), Positives = 26/46 (56%)
 Frame = -2

Query: 55   KKIKLQIWDTAGQERFRTITTAYYRGAMGIMLVYDITNEKSFDNIK 100
            ++++L +WDTAGQE +  +    Y     I++ + I +  S +NI 
Sbjct: 2729 QQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIP 2592
>18184
          Length = 558

 Score = 31.6 bits (70), Expect = 0.24,   Method: Compositional matrix adjust.
 Identities = 15/36 (41%), Positives = 21/36 (58%)
 Frame = -3

Query: 7   YLFKLLLIGDSGVGKTCLLFRFSEDAFNTTFISTIG 42
           YLF +LL G    G  CL+  F  ++F   F+ST+G
Sbjct: 442 YLFYILLTGIVQFGYCCLVGTFPFNSFLAGFVSTVG 335
>02923
          Length = 569

 Score = 30.4 bits (67), Expect = 0.53,   Method: Compositional matrix adjust.
 Identities = 29/120 (24%), Positives = 53/120 (44%), Gaps = 3/120 (2%)
 Frame = +2

Query: 58  KLQIWDTAGQ---ERFRTITTAYYRGAMGIMLVYDITNEKSFDNIKNWIRNIEEHASSDV 114
           ++Q++D AG+   +R+  I  A   G  GIM ++   ++ SFD I   +          +
Sbjct: 35  QIQLFD-AGETALKRYDHILPACQDGVDGIMFLFSFVDKGSFDEIPQLLTRFTT-LEDGI 208

Query: 115 ERMILGNKCDMNDKRQVSKERGEKLAIDYGIKFLETSAKSSTNVEEAFFTLARDIMTKLN 174
            ++ LG K D++   +V++     L   + I  L      +    E+   L  DI+  LN
Sbjct: 209 CKIALGTKFDLHAHSEVTQRDIRDLENTWKIPVLRIRNLQNPQQAESSGGLG-DIIPVLN 385
>11299
          Length = 2019

 Score = 29.3 bits (64), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 13/32 (40%), Positives = 19/32 (59%)
 Frame = +2

Query: 160  EAFFTLARDIMTKLNRKMNDSNSSGAGGPVKI 191
            +AFFT+  D   K+N K  + NS   G P+K+
Sbjct: 1223 QAFFTIVCDSTCKINCKKQNQNSKQ*GRPLKL 1318
>31593
          Length = 646

 Score = 27.3 bits (59), Expect = 3.9,   Method: Compositional matrix adjust.
 Identities = 11/26 (42%), Positives = 17/26 (65%)
 Frame = -3

Query: 109 HASSDVERMILGNKCDMNDKRQVSKE 134
           HA+ +VE + + N C+ ND  QV +E
Sbjct: 545 HATWEVESVFVSNLCNCNDLIQVVRE 468
>29444
          Length = 924

 Score = 27.3 bits (59), Expect = 4.5,   Method: Compositional matrix adjust.
 Identities = 13/24 (54%), Positives = 16/24 (66%), Gaps = 2/24 (8%)
 Frame = -3

Query: 104 RNIEEHASSDVERMI--LGNKCDM 125
           RNIEEH+SS + R +  LG  C M
Sbjct: 697 RNIEEHSSSQISRRLRELGRLCKM 626
>12784
          Length = 2199

 Score = 26.6 bits (57), Expect = 7.1,   Method: Compositional matrix adjust.
 Identities = 14/25 (56%), Positives = 16/25 (64%)
 Frame = +2

Query: 181  NSSGAGGPVKITESRSKKTSFFRCS 205
            N SGAGG +K   +RS   SFF CS
Sbjct: 1835 NVSGAGGSMKSKCTRSSIPSFFSCS 1909
>06048
          Length = 2527

 Score = 26.6 bits (57), Expect = 8.4,   Method: Compositional matrix adjust.
 Identities = 15/44 (34%), Positives = 23/44 (52%)
 Frame = -1

Query: 16  DSGVGKTCLLFRFSEDAFNTTFISTIGIDFKIRTIELDGKKIKL 59
           D  V   C+L +  EDAF  T +    +  K++ I L  +K+KL
Sbjct: 988 DKAVF*RCILHKCFEDAFYVTVLKDREV--KVKIINLKHRKVKL 863
>32321
          Length = 274

 Score = 26.6 bits (57), Expect = 8.5,   Method: Compositional matrix adjust.
 Identities = 15/36 (41%), Positives = 20/36 (55%)
 Frame = +2

Query: 112 SDVERMILGNKCDMNDKRQVSKERGEKLAIDYGIKF 147
           S +ER+  G K     KRQ  KERGE  A+D  ++ 
Sbjct: 35  SAIERLRKG-KSGKGRKRQKEKERGEGRAVDGSVRV 139
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|38372905|ref|NP_075615.2| cell line NK14 derived
transforming oncogene [Mus musculus]
         (207 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

08428                                                                 142   8e-35
34468                                                                 141   2e-34
33374                                                                 106   7e-29
34597                                                                 111   6e-28
33794                                                                 119   1e-27
26083                                                                 112   8e-26
33380                                                                 107   9e-26
05468                                                                 110   4e-25
07465                                                                 105   1e-23
14456                                                                 100   6e-22
32723                                                                  99   2e-21
07580                                                                  98   2e-21
17511                                                                  98   3e-21
30760                                                                  98   3e-21
01398                                                                  95   2e-20
11257                                                                  90   6e-19
13901                                                                  87   4e-18
19006                                                                  87   5e-18
01972                                                                  75   3e-17
12339                                                                  82   1e-16
13750                                                                  80   4e-16
35581                                                                  79   2e-15
00858                                                                  77   6e-15
11728                                                                  77   6e-15
27191                                                                  77   7e-15
13745                                                                  76   1e-14
01095                                                                  75   2e-14
19656                                                                  73   7e-14
26536                                                                  72   1e-13
34359                                                                  59   9e-12
19046                                                                  64   3e-11
24619                                                                  63   9e-11
09204                                                                  60   7e-10
09827                                                                  55   2e-08
08153                                                                  52   2e-07
14775                                                                  50   7e-07
29380                                                                  50   9e-07
00552                                                                  49   2e-06
31291                                                                  49   2e-06
18509                                                                  48   3e-06
10862                                                                  46   1e-05
33605                                                                  45   2e-05
25796                                                                  45   2e-05
12443                                                                  44   5e-05
14119                                                                  42   2e-04
10708                                                                  36   0.011
18184                                                                  31   0.39 
02923                                                                  30   0.67 
18949                                                                  28   2.6  
31593                                                                  28   3.2  
>08428
          Length = 1109

 Score =  142 bits (359), Expect = 8e-35,   Method: Compositional matrix adjust.
 Identities = 64/172 (37%), Positives = 103/172 (59%)
 Frame = -3

Query: 10   KLLLIGDSGVGKTCVLFRFSEDAFNSTFISTIGIDFKIRTIELDGKRIKLQIWDTAGQER 69
            K+ L+GDSGVGK+ ++ RF   ++  +  STIG  F  +++ +DG   + QIWDTAGQE+
Sbjct: 1065 KVCLLGDSGVGKSSIVLRFVTGSYRPSQESTIGASFMSKSLVVDGAGYRFQIWDTAGQEK 886

Query: 70   FRTITTAYYRGAMGIMLVYDITNEKSFDNIRNWIRNIEEHASADVEKMILGNKCDVNDKR 129
            FR +   YYRGA   ++VYD+T  ++F ++++WI+ +      ++   I GNKCD+ + R
Sbjct: 885  FRALAPMYYRGAAAAVIVYDVTRPRTFKSVKSWIQELRSFGPPNIVLAIAGNKCDLEELR 706

Query: 130  QVSKERGEKLALDYGIKFMETSAKANINVENAFFTLARDIKAKMDKKLEGNS 181
            +V ++  ++ A      F ETSA   +NVE  F  LAR +  + D     N+
Sbjct: 705  EVVEKDAQEYASSISAIFGETSAMTAVNVEEMFTELARQLPPEEDNPHPSNT 550
>34468
          Length = 1502

 Score =  141 bits (356), Expect = 2e-34,   Method: Compositional matrix adjust.
 Identities = 75/195 (38%), Positives = 116/195 (59%), Gaps = 9/195 (4%)
 Frame = +1

Query: 3   KTYDYLFKLLLIGDSGVGKTCVLFRFSEDAFNSTFISTIGIDFKIRTIELDGKRIKLQIW 62
           +T   +FK+++IGDS VGKTC+ +RF    F     +TIG+DF+ ++I++D + +KLQ+W
Sbjct: 478 QTQRRIFKIIVIGDSNVGKTCLTYRFCLGKFPDKTEATIGVDFREKSIQVDSEHLKLQLW 657

Query: 63  DTAGQERFR-TITTAYYRGAMGIMLVYDITNEKSFDNIRNWIRNIEEH-ASADVEKMILG 120
           DTAGQERFR ++   YYR    ++ VYD+T   SF+N+  WI   + H  +  + ++++G
Sbjct: 658 DTAGQERFRKSMVQHYYRNVHAVVFVYDMTKMSSFENMPAWIEECDRHNLTKYIPRILVG 837

Query: 121 NKCDVNDKRQVSKERGEKLALDYGIKFMETSA----KANINVENAFFTLARDI---KAKM 173
           NKCDV ++  V+    +K A  + +   ETSA    KAN +V+  F T+A  +   K  M
Sbjct: 838 NKCDVVERIAVNTNLAQKFADAHNMPLFETSAKDDEKAN-HVDAIFMTVAHKLKXSKPMM 1014

Query: 174 DKKLEGNSPQGSSHG 188
              L    P   SHG
Sbjct: 1015PAHLSEMVPGDVSHG 1059
>33374
          Length = 489

 Score =  106 bits (264), Expect(2) = 7e-29,   Method: Compositional matrix adjust.
 Identities = 47/116 (40%), Positives = 73/116 (62%)
 Frame = +1

Query: 45  FKIRTIELDGKRIKLQIWDTAGQERFRTITTAYYRGAMGIMLVYDITNEKSFDNIRNWIR 104
           F  +T+ LD   +K +IWDTAGQER+ ++   YYRGA   ++VYDITN+ +F   + W++
Sbjct: 139 FLTQTVCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNQDTFGRAKTWVK 318

Query: 105 NIEEHASADVEKMILGNKCDVNDKRQVSKERGEKLALDYGIKFMETSAKANINVEN 160
            ++  AS ++   + GNK D+ +KR V  E  +  A +  + FMETSAK  +NV +
Sbjct: 319 ELQRQASPNIVIALAGNKADLANKRMVEFEEAQAYAEENSLLFMETSAKTAMNVND 486

 Score = 37.7 bits (86), Expect(2) = 7e-29,   Method: Compositional matrix adjust.
 Identities = 19/44 (43%), Positives = 28/44 (63%)
 Frame = +2

Query: 9  FKLLLIGDSGVGKTCVLFRFSEDAFNSTFISTIGIDFKIRTIEL 52
          FKL+L+G+S VGK+ ++ RF +  F+    STIG  F +R   L
Sbjct: 32 FKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAF*LRQFVL 163
>34597
          Length = 773

 Score =  111 bits (278), Expect(2) = 6e-28,   Method: Compositional matrix adjust.
 Identities = 54/90 (60%), Positives = 68/90 (75%)
 Frame = -2

Query: 94  KSFDNIRNWIRNIEEHASADVEKMILGNKCDVNDKRQVSKERGEKLALDYGIKFMETSAK 153
           KSF+NI  W+RNI+EHA+ DVEKMILGNKCD+ DKR VSKERGE +A ++ I+FMETSAK
Sbjct: 712 KSFENIVKWLRNIDEHANEDVEKMILGNKCDMTDKRVVSKERGEAIAREHSIRFMETSAK 533

Query: 154 ANINVENAFFTLARDIKAKMDKKLEGNSPQ 183
           +NIN+E AF  LA  I  K   +    +P+
Sbjct: 532 SNINIERAFCELAEAILDKTAGRESAENPE 443

 Score = 28.9 bits (63), Expect(2) = 6e-28,   Method: Compositional matrix adjust.
 Identities = 12/13 (92%), Positives = 13/13 (100%)
 Frame = -3

Query: 75  TAYYRGAMGIMLV 87
           T+YYRGAMGIMLV
Sbjct: 771 TSYYRGAMGIMLV 733
>33794
          Length = 779

 Score =  119 bits (297), Expect = 1e-27,   Method: Compositional matrix adjust.
 Identities = 58/125 (46%), Positives = 82/125 (65%)
 Frame = -1

Query: 43  IDFKIRTIELDGKRIKLQIWDTAGQERFRTITTAYYRGAMGIMLVYDITNEKSFDNIRNW 102
           + +K  TI L+GKR+KLQIWDT+GQ RF TI  +Y RGA GI+LVYDITN+ SFD I  W
Sbjct: 692 VAYKTTTILLEGKRVKLQIWDTSGQGRFCTIIRSYSRGAQGIILVYDITNKWSFDGIDRW 513

Query: 103 IRNIEEHASADVEKMILGNKCDVNDKRQVSKERGEKLALDYGIKFMETSAKANINVENAF 162
           ++ +EEHA   + K+++GN+  +  KRQV+ ++ E  A    +   E S   + N+  +F
Sbjct: 512 LKEVEEHAPG-IPKVLVGNRLHLAYKRQVAAKQAETYASRNNMSCFEISPLCDFNIRESF 336

Query: 163 FTLAR 167
             LAR
Sbjct: 335 CELAR 321
>26083
          Length = 432

 Score =  112 bits (281), Expect = 8e-26,   Method: Compositional matrix adjust.
 Identities = 52/114 (45%), Positives = 79/114 (69%)
 Frame = +1

Query: 9   FKLLLIGDSGVGKTCVLFRFSEDAFNSTFISTIGIDFKIRTIELDGKRIKLQIWDTAGQE 68
           FKL+ +G+  VGKT ++ RF  D+F++T+ +TIGIDF  +T+ L+ + I+LQ+WDTAGQE
Sbjct: 79  FKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTIRLQLWDTAGQE 258

Query: 69  RFRTITTAYYRGAMGIMLVYDITNEKSFDNIRNWIRNIEEHASADVEKMILGNK 122
           RFR++  +Y R +   ++VYDITN  SF     WI ++     +DV  M++GNK
Sbjct: 259 RFRSLIPSYIRDSSVAVVVYDITNANSFHQTSKWIDDVRTERGSDVIIMLVGNK 420
>33380
          Length = 282

 Score =  107 bits (266), Expect(2) = 9e-26,   Method: Compositional matrix adjust.
 Identities = 44/75 (58%), Positives = 64/75 (85%)
 Frame = +3

Query: 55  KRIKLQIWDTAGQERFRTITTAYYRGAMGIMLVYDITNEKSFDNIRNWIRNIEEHASADV 114
           KR+KLQIWDTAGQER+RTITTAYYRGAMG +L+YD+TNE+SF+ +++W   I+ ++  + 
Sbjct: 54  KRVKLQIWDTAGQERYRTITTAYYRGAMGFILMYDVTNEESFNAVQDWCTQIKTYSWDNA 233

Query: 115 EKMILGNKCDVNDKR 129
           + +++GNKCD+ D+R
Sbjct: 234 QVVLVGNKCDLEDER 278

 Score = 26.6 bits (57), Expect(2) = 9e-26,   Method: Compositional matrix adjust.
 Identities = 8/15 (53%), Positives = 14/15 (93%)
 Frame = +2

Query: 37 FISTIGIDFKIRTIE 51
          F+ST+GIDFK+ +++
Sbjct: 2  FVSTVGIDFKVNSLQ 46
>05468
          Length = 1558

 Score =  110 bits (275), Expect = 4e-25,   Method: Compositional matrix adjust.
 Identities = 60/167 (35%), Positives = 98/167 (58%), Gaps = 11/167 (6%)
 Frame = -3

Query: 6    DYLFKLLLIGDSGVGKTCVLFRFSEDAFNSTFISTIGIDFKIRTIELDGKR-IKLQIWDT 64
            ++L+K+L+IG+ G GKT ++ R+    F+  + +TIG+DF ++ +  D    I+LQ+WD 
Sbjct: 1547 EHLYKILVIGELGTGKTSIIKRYVHQFFSQHYRATIGVDFALKVLNWDADTLIRLQLWDI 1368

Query: 65   AGQERFRTITTAYYRGAMGIMLVYDITNEKSFDNIRNWIRNIEEHAS----ADVEKMILG 120
            AGQERF  +T  YY+ A+G  +V+D+T   +FD +  W  +++        + V  ++L 
Sbjct: 1367 AGQERFGNMTRVYYKEAVGAFVVFDVTRASTFDAVTKWKNDLDSKVQLADGSPVPCVLLA 1188

Query: 121  NKCD------VNDKRQVSKERGEKLALDYGIKFMETSAKANINVENA 161
            NKCD      VN+  Q+ +   EK      I + ETSAK NIN++ A
Sbjct: 1187 NKCDQAKEGLVNNTSQMDEFCSEKGF----IGWYETSAKENINIDEA 1059
>07465
          Length = 1103

 Score =  105 bits (263), Expect = 1e-23,   Method: Compositional matrix adjust.
 Identities = 54/145 (37%), Positives = 82/145 (56%)
 Frame = +3

Query: 22  TCVLFRFSEDAFNSTFISTIGIDFKIRTIELDGKRIKLQIWDTAGQERFRTITTAYYRGA 81
           + ++ R+ +  F   +  TIG+DF  R IE+ G+ ++L +WDTAGQE F  IT AYYRGA
Sbjct: 240 SSMIQRYCKGIFTKDYKKTIGVDFLERQIEVGGEDVRLMLWDTAGQEEFDAITKAYYRGA 419

Query: 82  MGIMLVYDITNEKSFDNIRNWIRNIEEHASADVEKMILGNKCDVNDKRQVSKERGEKLAL 141
              +L +   +  SF+ +  W R +E+    ++  +I+ NK D+ D   V  E  E LA 
Sbjct: 420 QACVLAFSTVDRDSFEALETWKRKVEDEV-GEIGMVIVQNKIDLIDDAVVRPEEAENLAK 596

Query: 142 DYGIKFMETSAKANINVENAFFTLA 166
              ++F  TS K N+NV+  F  LA
Sbjct: 597 KLRLRFYRTSVKENMNVDEVFRYLA 671
>14456
          Length = 1867

 Score =  100 bits (248), Expect = 6e-22,   Method: Compositional matrix adjust.
 Identities = 57/193 (29%), Positives = 102/193 (52%), Gaps = 6/193 (3%)
 Frame = -1

Query: 18   GVGKTCVLFRFSEDAFNSTFISTIGIDFKIRTIELDGKRIKLQIWDTAGQERFRTITTAY 77
            GVGK+ ++ RF  + F++    TIG++F  + + +D +   +QIWDTAGQERF+++ T +
Sbjct: 1111 GVGKSSLMNRFVSNKFDAQSFHTIGVEFLNKDVVVDDETYTMQIWDTAGQERFKSLRTPF 932

Query: 78   YRGAMGIMLVYDITNEKSFDNIRNWIRNIEEHASADVEK------MILGNKCDVNDKRQV 131
            YRGA   +L + + + +SF N+  W +    +  AD++       ++LGNK DV  ++  
Sbjct: 931  YRGADCCLLTFSVDSMQSFRNLSMWRKEFLYY--ADIQDGVTFPFVVLGNKIDVEGRQVT 758

Query: 132  SKERGEKLALDYGIKFMETSAKANINVENAFFTLARDIKAKMDKKLEGNSPQGSSHGVKI 191
            ++E       +    + ETSAK   NVE AF    + +     +++E      ++HG  +
Sbjct: 757  NEEARSWCTANSNAPYFETSAKDATNVEKAFLAAVQRL-----REVEDQQEVKTAHGNTV 593

Query: 192  TVEQQKRTSFFRC 204
             + +  R     C
Sbjct: 592  DLNRAARGKSSSC 554
>32723
          Length = 384

 Score = 98.6 bits (244), Expect = 2e-21,   Method: Compositional matrix adjust.
 Identities = 46/111 (41%), Positives = 71/111 (63%)
 Frame = +2

Query: 67  QERFRTITTAYYRGAMGIMLVYDITNEKSFDNIRNWIRNIEEHASADVEKMILGNKCDVN 126
           QERFR+IT +YYR A  ++LVYD+ +++S++++  WI  IE +A   V   ++GNK D  
Sbjct: 2   QERFRSITQSYYRSANALILVYDVCSQQSYESLPQWIHEIELYAGTKVLAFLVGNKIDQT 181

Query: 127 DKRQVSKERGEKLALDYGIKFMETSAKANINVENAFFTLARDIKAKMDKKL 177
           DKR++    G++ A  Y ++F+ETSAK   NVE  F T+A  + A+    L
Sbjct: 182 DKREIPTHIGKEFAERYEMRFLETSAKEADNVEKLFSTIAYQLTAQAQGTL 334
>07580
          Length = 921

 Score = 98.2 bits (243), Expect = 2e-21,   Method: Compositional matrix adjust.
 Identities = 57/173 (32%), Positives = 91/173 (52%), Gaps = 1/173 (0%)
 Frame = +3

Query: 19  VGKTCVLFRFSEDAFNSTFISTIGIDFKIRTIELDGKRIKLQIWDTAGQERFRTITTAYY 78
           + K   L+   +  F   +  TI   ++ + +E+DG++  L+I DTAG E+F  +   Y 
Sbjct: 93  LAKVL*LYSLCKGIFVEKYDPTIEDSYR-KQVEVDGQQCMLEILDTAGTEQFTAMRDLYM 269

Query: 79  RGAMGIMLVYDITNEKSFDNIRNWIRNI-EEHASADVEKMILGNKCDVNDKRQVSKERGE 137
           +   G +L Y IT + +F++++     I     + DV  +++GNKCD+ D+R V K++G+
Sbjct: 270 KNGQGFLLAYSITAQSTFNDLQELREQILRVKDTDDVPMLLVGNKCDLEDERVVGKDQGQ 449

Query: 138 KLALDYGIKFMETSAKANINVENAFFTLARDIKAKMDKKLEGNSPQGSSHGVK 190
            LA  +   F+ETSAKA INV   F  L R I  K        SP+ S    K
Sbjct: 450 GLARSFSCAFLETSAKARINVNEIFMDLVRQINKK--------SPEQSGKRTK 584
>17511
          Length = 483

 Score = 97.8 bits (242), Expect = 3e-21,   Method: Compositional matrix adjust.
 Identities = 49/129 (37%), Positives = 82/129 (63%), Gaps = 4/129 (3%)
 Frame = -3

Query: 1   MAKTYDYLFKLLLIGDSGVGKTCVLFRFSEDAFNSTFISTIGIDFKIRTIELDGKRIKLQ 60
           MA     L K++++GDSGVGKT ++ ++    F++ + +TIG DF  + + +D + + +Q
Sbjct: 388 MASRKKVLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQ 209

Query: 61  IWDTAGQERFRTITTAYYRGAMGIMLVYDITNEKSFDNIRNWIRNIEEHASA-DVEK--- 116
           IWDTAGQERF+++  A+YRGA   +LV+D+T   +F ++ +W       AS  D E    
Sbjct: 208 IWDTAGQERFQSLGVAFYRGADCCVLVFDVTMPNTFRSLDSWRDEFLIQASPRDPENFPF 29

Query: 117 MILGNKCDV 125
           +++GNK D+
Sbjct: 28  VVIGNKIDL 2
>30760
          Length = 596

 Score = 97.8 bits (242), Expect = 3e-21,   Method: Compositional matrix adjust.
 Identities = 50/174 (28%), Positives = 96/174 (55%), Gaps = 5/174 (2%)
 Frame = -1

Query: 10  KLLLIGDSGVGKT--CVLFRFSEDAFNSTFISTIGIDFKIRTIELDGKR--IKLQIWDTA 65
           K ++ GDSGVGK+  C +F      F   +  T G++  ++ + +   R  ++L ++D+A
Sbjct: 524 KCIVTGDSGVGKSSICQVFHSDSAHFPKNYSMTTGVEVLVKLVNIPDSRDQVELYLFDSA 345

Query: 66  GQERFRTITTAYYRGAMGIMLVYDITNEKSFDNIRNWIRNIE-EHASADVEKMILGNKCD 124
           G+E F    T ++     +M+VYD+T+E SF     W+  +     +  +  +++ NK D
Sbjct: 344 GKEIFSENVTKFWDQPSVVMVVYDVTDETSFSGCVRWLERVRAAKPNTVIPGVLVANKTD 165

Query: 125 VNDKRQVSKERGEKLALDYGIKFMETSAKANINVENAFFTLARDIKAKMDKKLE 178
           ++++R+VS++ G+ LA  +G+++ E SAK   N +  FF LA        ++L+
Sbjct: 164 LDERRRVSRKEGKDLAQSHGLEYFECSAKEMQNTDTPFFCLAHAFHKLYQEQLQ 3
>01398
          Length = 1421

 Score = 94.7 bits (234), Expect = 2e-20,   Method: Compositional matrix adjust.
 Identities = 45/106 (42%), Positives = 70/106 (66%), Gaps = 4/106 (3%)
 Frame = -2

Query: 67   QERFRTITTAYYRGAMGIMLVYDITNEKSFDNIRNWIR----NIEEHASADVEKMILGNK 122
            QERFR+IT +YYR ++G+++VYDIT   +F+N++ W      +IE H +     ++LG+K
Sbjct: 1420 QERFRSITRSYYRNSVGVIIVYDITKRSTFENLKQWYEEARNHIEPHKAI---FLVLGHK 1250

Query: 123  CDVNDKRQVSKERGEKLALDYGIKFMETSAKANINVENAFFTLARD 168
             D  D RQV+   G + A  +G+KF ETSAK+  N+E+ F  +A+D
Sbjct: 1249 SDREDARQVTAREGRRFAEMHGLKFFETSAKSGHNIEDVFAQIAKD 1112
>11257
          Length = 1102

 Score = 90.1 bits (222), Expect = 6e-19,   Method: Compositional matrix adjust.
 Identities = 46/136 (33%), Positives = 83/136 (61%), Gaps = 5/136 (3%)
 Frame = -2

Query: 48   RTIELDGKRIKLQIWDTAGQERFRTITTAYYRGAMGIMLVYDITNEKSFDNIRNWIRNIE 107
            + + +DG+   +QIWDTAGQER++++ T +YRG    +L + + N KS  ++ +W     
Sbjct: 1053 KDVVVDGETFTMQIWDTAGQERYKSLRTPFYRGTDCCLLTFSVDNLKSLQSLSDWYDEFV 874

Query: 108  EHA----SADVEKMILGNKCDVNDKRQVSKERGEKLALDYG-IKFMETSAKANINVENAF 162
             +A    SA    +I+GNK D+ ++R+VS E        +G + + ETSAK ++NV+ AF
Sbjct: 873  NYADIQDSASFPFVIIGNKADI-EEREVSSEDAYNWCRTHGNLPYFETSAKDSLNVQQAF 697

Query: 163  FTLARDIKAKMDKKLE 178
              + R ++ +MD++++
Sbjct: 696  LAVVRRLR-EMDEQMD 652
>13901
          Length = 962

 Score = 87.0 bits (214), Expect = 4e-18,   Method: Compositional matrix adjust.
 Identities = 40/96 (41%), Positives = 62/96 (64%), Gaps = 1/96 (1%)
 Frame = -3

Query: 8   LFKLLLIGDSGVGKTCVLFRFSEDAFNSTFISTIGIDFKIRTIELDGK-RIKLQIWDTAG 66
           LFK+++IGD  VGKT  + R+  D+F   +  TIG+DF ++ I    K  IKLQ+WD AG
Sbjct: 288 LFKVIIIGDPTVGKTSFVQRYVNDSFRRDYKMTIGVDFALKVIRWSDKCNIKLQLWDIAG 109

Query: 67  QERFRTITTAYYRGAMGIMLVYDITNEKSFDNIRNW 102
           QERF ++T  YY+ A   ++++D+T + ++ N   W
Sbjct: 108 QERFTSMTRVYYKDAHACIVMFDLTQKNTYQNAIRW 1
>19006
          Length = 568

 Score = 87.0 bits (214), Expect = 5e-18,   Method: Compositional matrix adjust.
 Identities = 46/138 (33%), Positives = 79/138 (57%), Gaps = 5/138 (3%)
 Frame = -2

Query: 10  KLLLIGDSGVGKTCVLFRFSEDAFNSTFISTIGIDFKIRTIELDGKRIKLQIWDTAGQER 69
           KL+++GD   GKTC+L  FS+D F   ++ T+  ++ +  IE+D K+++L +WDTAGQE 
Sbjct: 432 KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENY-VADIEVDSKQVELALWDTAGQED 256

Query: 70  FRTITTAYYRGAMGIMLVYDITNEKSFDNI-RNWIRNIEEHASADVEKMILGNKCDV--- 125
           +  +    Y     I++ + I +  S +NI   W   +  H   +V  +++GNK D+   
Sbjct: 255 YDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEV-RHFCPNVPIILVGNKKDLRND 79

Query: 126 -NDKRQVSKERGEKLALD 142
            N KR++ K + E + LD
Sbjct: 78  ENTKRELMKMKQEPVRLD 25
>01972
          Length = 2359

 Score = 75.1 bits (183), Expect(2) = 3e-17,   Method: Compositional matrix adjust.
 Identities = 35/133 (26%), Positives = 71/133 (53%)
 Frame = +3

Query: 37  FISTIGIDFKIRTIELDGKRIKLQIWDTAGQERFRTITTAYYRGAMGIMLVYDITNEKSF 96
           +++T+G++           ++K  +WDTAGQE+F  +   YY      ++++D+T+  ++
Sbjct: 387 YVATLGVEVHPLLFHTSRGKLKFNVWDTAGQEKFGGLRDGYYIQGQCAVIMFDVTSRVTY 566

Query: 97  DNIRNWIRNIEEHASADVEKMILGNKCDVNDKRQVSKERGEKLALDYGIKFMETSAKANI 156
            N+ NW R++      ++  ++ GNK D+ D++   K +         +++ + SAK+N 
Sbjct: 567 KNVPNWHRDLVR-VCENIPIVLCGNKVDIKDRK--VKAKAIVFHRKKNLQYYDISAKSNY 737

Query: 157 NVENAFFTLARDI 169
           N E  F  LAR +
Sbjct: 738 NFEKPFLWLARKL 776

 Score = 30.0 bits (66), Expect(2) = 3e-17,   Method: Compositional matrix adjust.
 Identities = 13/31 (41%), Positives = 17/31 (54%)
 Frame = +1

Query: 9   FKLLLIGDSGVGKTCVLFRFSEDAFNSTFIS 39
           FKL+L+GD GVGKT  + R     F    + 
Sbjct: 304 FKLVLVGDGGVGKTTFVKRHVTGEFEKNMLP 396
>12339
          Length = 578

 Score = 82.4 bits (202), Expect = 1e-16,   Method: Compositional matrix adjust.
 Identities = 48/111 (43%), Positives = 71/111 (63%), Gaps = 5/111 (4%)
 Frame = -2

Query: 67  QERFRTITTAYYRGAMGIMLVYDITNEKSFDNIRNWIRNIEEHASA-DVEK---MILGNK 122
           QERF+++  A+YRGA   +LVYD+T  K+FD++ +W R     AS  D E    +++GNK
Sbjct: 577 QERFQSLGVAFYRGADCCILVYDVTEXKTFDSLDSWQREFLNQASPRDPEHFPFVVIGNK 398

Query: 123 CDVNDKRQVSKERGEK-LALDYGIKFMETSAKANINVENAFFTLARDIKAK 172
            D+ D R V+ +RG+   +   GI + ETSAK  INVE AF T+A++  A+
Sbjct: 397 IDL-DNRVVTAKRGQGWCSTKGGIPYFETSAKEAINVEQAFQTVAKNALAQ 248
>13750
          Length = 503

 Score = 80.5 bits (197), Expect = 4e-16,   Method: Compositional matrix adjust.
 Identities = 48/150 (32%), Positives = 79/150 (52%), Gaps = 4/150 (2%)
 Frame = -2

Query: 21  KTCVLFRFSEDAFNSTFISTIGI---DF-KIRTIELDGKRIKLQIWDTAGQERFRTITTA 76
           KTC+L R+ +  F    + TI +   +F + RT   D   ++  +WDT G E +R++  +
Sbjct: 502 KTCLLRRYQKGFFMDRTMPTIAVLCSEFNESRT---DPLNVRYTLWDTGGAETYRSLWVS 332

Query: 77  YYRGAMGIMLVYDITNEKSFDNIRNWIRNIEEHASADVEKMILGNKCDVNDKRQVSKERG 136
           ++RGA   +LVYD+T E SF       R        + + + +G+K D+ + R +S ERG
Sbjct: 331 HFRGAQVALLVYDVTCEWSFLTATTVWRKALMKNIPEAQVIFVGSKTDLEENRVISTERG 152

Query: 137 EKLALDYGIKFMETSAKANINVENAFFTLA 166
           +  A   G  F ETS+    NV+  F+ +A
Sbjct: 151 QAFATQCGYTFFETSSVTGKNVDAVFWEIA 62
>35581
          Length = 364

 Score = 78.6 bits (192), Expect = 2e-15,   Method: Compositional matrix adjust.
 Identities = 34/82 (41%), Positives = 56/82 (68%), Gaps = 1/82 (1%)
 Frame = +2

Query: 9   FKLLLIGDSGVGKTCVLFRFSEDAFNSTFISTIGIDFKIRTIEL-DGKRIKLQIWDTAGQ 67
           FK +L+GD+GVGKTC+L R + D F  + ++++     + T+ L  G    + +WDTAGQ
Sbjct: 47  FKCVLLGDAGVGKTCLLNRLATDKFLDSPLTSLTTASLLTTVTLTSGVMASVDLWDTAGQ 226

Query: 68  ERFRTITTAYYRGAMGIMLVYD 89
           ER+R++T++YYR    +++VYD
Sbjct: 227 ERYRSLTSSYYRDTKAVLIVYD 292
>00858
          Length = 1658

 Score = 77.0 bits (188), Expect = 6e-15,   Method: Compositional matrix adjust.
 Identities = 55/162 (33%), Positives = 89/162 (54%), Gaps = 1/162 (0%)
 Frame = -2

Query: 9    FKLLLIGDSGVGKTCVLFRFSEDAFNSTFISTIGIDFKIRTIELDGKRIKLQIWDTAGQE 68
            +KL+++G  GVGK+ +  +  ++ F   +  T   D   + + +DG+   L I DTAGQE
Sbjct: 1588 YKLVVVGAGGVGKSALTIQLXQNHFVEEYDPTXE-DSXRKQVVIDGETCLLDILDTAGQE 1412

Query: 69   RFRTITTAYYRGAMGIMLVYDITNEKSFDNIRNWIRNIEEHASADVEKMIL-GNKCDVND 127
                +     R   G + V+ + N KSF++I  +   I+    AD   M+L GNK D+  
Sbjct: 1411 EXSAMRDQCMRTGEGFLCVFAVXNLKSFEDINQYREQIKRVKDADEVPMVLVGNKVDLP- 1235

Query: 128  KRQVSKERGEKLALDYGIKFMETSAKANINVENAFFTLARDI 169
             R V + +G+ +A  Y I ++ETSAK    V++AF+TL R+I
Sbjct: 1234 IRNVEQRQGKHMAELYHIPYVETSAKTRQGVDDAFYTLVREI 1109
>11728
          Length = 635

 Score = 76.6 bits (187), Expect = 6e-15,   Method: Compositional matrix adjust.
 Identities = 40/134 (29%), Positives = 71/134 (52%), Gaps = 2/134 (1%)
 Frame = -1

Query: 9   FKLLLIGDSGVGKTCVLFRFSEDAFNSTFISTIGIDFKIRTIELDGKRIKLQIWDTAGQE 68
            K +++GD  VGKTC+L  ++ +AF   +I T+  D     + +D K I L +WDTAGQE
Sbjct: 488 IKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTV-FDNYSANVMVDSKPINLGLWDTAGQE 312

Query: 69  RFRTITTAYYRGAMGIMLVYDITNEKSFDNIR-NWIRNIEEHASADVEKMILGNKCDV-N 126
            +  +    Y      ++ + + +  SF+N++  W   +  H   +   +++G K D+  
Sbjct: 311 DYDRLRPLSYPQTDVFLICFSLISPASFENVKAKWYPEVSHHCP-NTPIILVGTKLDLRE 135

Query: 127 DKRQVSKERGEKLA 140
           DK  + K + +KLA
Sbjct: 134 DKETIEKLKEKKLA 93
>27191
          Length = 443

 Score = 76.6 bits (187), Expect = 7e-15,   Method: Compositional matrix adjust.
 Identities = 32/117 (27%), Positives = 64/117 (54%)
 Frame = +1

Query: 21  KTCVLFRFSEDAFNSTFISTIGIDFKIRTIELDGKRIKLQIWDTAGQERFRTITTAYYRG 80
           KTC++  F E  FN  +  T+G+D+  +   ++G  +++ +WD +G   +  +    Y G
Sbjct: 1   KTCLIKHFCESKFNQGYQPTVGVDYGFKIQTVNGVDMRVHMWDLSGSNEYLDVRNELYTG 180

Query: 81  AMGIMLVYDITNEKSFDNIRNWIRNIEEHASADVEKMILGNKCDVNDKRQVSKERGE 137
           +  I +V+D++N  SF+ + +W+R I   A+     +I+GN+   N   Q  +++ E
Sbjct: 181 SDAIFIVFDVSNTPSFEALDSWLREINRFATGSPLNVIVGNRVI*NRSAQCRQQKQE 351
>13745
          Length = 1045

 Score = 75.9 bits (185), Expect = 1e-14,   Method: Compositional matrix adjust.
 Identities = 47/107 (43%), Positives = 64/107 (59%), Gaps = 5/107 (4%)
 Frame = +2

Query: 67  QERFRTITTAYYRGAMGIMLVYDITNEKSFDNIRNWIRNIEEHASA-DVEK---MILGNK 122
           QERF+++  A+YRGA   +LVYD+T   SF N+ +W       AS  D E    ++LGNK
Sbjct: 2   QERFQSLGVAFYRGADCCVLVYDVTAPNSFKNLDSWRDEFLIQASPRDPEHFPFVVLGNK 181

Query: 123 CDVNDKRQVSKERGEKLALDYG-IKFMETSAKANINVENAFFTLARD 168
            D+ D RQVS  R ++       I + ETSAK  INVE AF T+A++
Sbjct: 182 VDL-DNRQVSTRRAQQWCQSKNDIPYYETSAKEGINVEMAFQTIAKN 319
>01095
          Length = 1745

 Score = 74.7 bits (182), Expect = 2e-14,   Method: Compositional matrix adjust.
 Identities = 39/119 (32%), Positives = 65/119 (54%)
 Frame = -1

Query: 86   LVYDITNEKSFDNIRNWIRNIEEHASADVEKMILGNKCDVNDKRQVSKERGEKLALDYGI 145
            +VYDITN+ +F   + W++ ++  AS ++   + GNK D+ +KR V  E  +  A +  +
Sbjct: 1745 VVYDITNQDTFGRAKTWVKELQRQASPNIVIALAGNKADLANKRMVEFEEAQAYAEENSL 1566

Query: 146  KFMETSAKANINVENAFFTLARDIKAKMDKKLEGNSPQGSSHGVKITVEQQKRTSFFRC 204
             FMETSAK  +NV + F  +A+    K+ K   G   Q    GV++  EQ +++    C
Sbjct: 1565 LFMETSAKTAMNVNDIFLAIAK----KLPKNEGGGGSQPRQQGVRLNNEQSQQSEGGCC 1401
>19656
          Length = 428

 Score = 73.2 bits (178), Expect = 7e-14,   Method: Compositional matrix adjust.
 Identities = 33/104 (31%), Positives = 55/104 (52%), Gaps = 1/104 (0%)
 Frame = +3

Query: 10  KLLLIGDSGVGKTCVLFRFSEDAFNSTFISTIGIDFKIRTIELDGKRIKLQIWDTAGQER 69
           K +++GD  VGKTC+L  ++ +AF   +I T+  D     + +DG+ + L +WDTAGQE 
Sbjct: 117 KCVVVGDGAVGKTCLLISYTTNAFPGEYIPTV-FDNYSANVMVDGRPVNLGLWDTAGQED 293

Query: 70  FRTITTAYYRGAMGIMLVYDITNEKSFDNIR-NWIRNIEEHASA 112
           +  +    Y      +L + + +  SF+NIR  W   +  H   
Sbjct: 294 YDRLRPLSYPQTDVFLLCFSVASPASFENIRAKWYPEVNHHCPG 425
>26536
          Length = 829

 Score = 72.4 bits (176), Expect = 1e-13,   Method: Compositional matrix adjust.
 Identities = 38/119 (31%), Positives = 62/119 (52%), Gaps = 3/119 (2%)
 Frame = +2

Query: 55  KRIKLQIWDTAGQERFRTITTAYYRGAMGIMLVYDITNEKSF---DNIRNWIRNIEEHAS 111
           +R+     DTAGQE + ++   Y R   G ++VY +T+  SF   + +  W+   ++  S
Sbjct: 122 RRVSWTFLDTAGQEEYSSMREHYTRSGDGFIVVYSVTDVTSFQEAEAVFRWLTRFQDETS 301

Query: 112 ADVEKMILGNKCDVNDKRQVSKERGEKLALDYGIKFMETSAKANINVENAFFTLARDIK 170
             +  ++ GNK D+   R+V+ E G K+A   G+ + ETSAK   NV   +  L R I 
Sbjct: 302 --IHAVLCGNKTDLTSDRKVTPEEGRKMADRLGMLYFETSAKTGDNVSQVYHGLLRSIP 472
>34359
          Length = 1042

 Score = 58.9 bits (141), Expect(2) = 9e-12,   Method: Compositional matrix adjust.
 Identities = 31/127 (24%), Positives = 70/127 (55%), Gaps = 2/127 (1%)
 Frame = +3

Query: 9   FKLLLIGDSGVGKTCVLFRFSEDAFNSTFISTIGIDFKIRTIELDGKR--IKLQIWDTAG 66
           FKL+L+G        ++ R    +    +++T+G++  +  ++ +  R  ++  +WDTAG
Sbjct: 54  FKLVLVGGRWEWANNIVKRHVTGS*KK-YVATLGVE--VHPLQFNTSRGLLRFNVWDTAG 224

Query: 67  QERFRTITTAYYRGAMGIMLVYDITNEKSFDNIRNWIRNIEEHASADVEKMILGNKCDVN 126
           QE+F  +   YY      ++++D+T+  ++ N+ NW R++      ++  ++ GNK D+ 
Sbjct: 225 QEKFGGLRDGYYIQGTCAIIMFDVTSRVTYKNVPNWHRDLVR-VCENIPIVLCGNKVDIK 401

Query: 127 DKRQVSK 133
           D++  +K
Sbjct: 402 DRKVKAK 422

 Score = 26.9 bits (58), Expect(2) = 9e-12,   Method: Compositional matrix adjust.
 Identities = 11/33 (33%), Positives = 20/33 (60%)
 Frame = +2

Query: 137 EKLALDYGIKFMETSAKANINVENAFFTLARDI 169
            +L+ +  +++ + SAK+N N E  F  LAR +
Sbjct: 425 HRLSQEKNLQYYDISAKSNYNFEKPFLWLARKL 523
>19046
          Length = 445

 Score = 64.3 bits (155), Expect = 3e-11,   Method: Compositional matrix adjust.
 Identities = 40/108 (37%), Positives = 61/108 (56%), Gaps = 2/108 (1%)
 Frame = -2

Query: 67  QERFRTITTAYYRGAMGIMLVYDITNEKSFDNIRNWIRNIEEHASADVEKMIL-GNKCDV 125
           QE F  +   Y R   G +LV+ +T+ +SF+N+ N+   I      D   MIL  NK D+
Sbjct: 444 QEEFSAMREQYMRKGDGFLLVFSVTDFRSFENMANFHTQILRVKDRDSYPMILCANKVDL 265

Query: 126 NDKRQVSKERGEKLALDYGIKFMETSAK-ANINVENAFFTLARDIKAK 172
             +R+VS+E+   LA    I ++ETSAK   +NV+ AF  + R I+A+
Sbjct: 264 VHQRKVSEEQVRDLATRLRIPYIETSAKDPPLNVDLAFHQVVRVIRAQ 121
>24619
          Length = 509

 Score = 62.8 bits (151), Expect = 9e-11,   Method: Compositional matrix adjust.
 Identities = 39/108 (36%), Positives = 60/108 (55%), Gaps = 2/108 (1%)
 Frame = -2

Query: 67  QERFRTITTAYYRGAMGIMLVYDITNEKSFDNIRNWIRNIEEHASADVEKMIL-GNKCDV 125
           QE F  +   Y R   G +LV+ + + +SF+N+ N+   I      D   MIL  NK D+
Sbjct: 508 QEEFSAMREQYMRKGDGFLLVFSVIDYQSFENMVNFHTQILRVKDRDTYPMILCANKVDL 329

Query: 126 NDKRQVSKERGEKLALDYGIKFMETSAK-ANINVENAFFTLARDIKAK 172
             +R+VS+E+   LA    I ++ETSAK   +NV+ AF  + R I+A+
Sbjct: 328 VHQRKVSEEQVRDLATRLRIPYIETSAKDPPLNVDLAFHQVVRVIRAQ 185
>09204
          Length = 1051

 Score = 60.1 bits (144), Expect = 7e-10,   Method: Compositional matrix adjust.
 Identities = 34/104 (32%), Positives = 55/104 (52%), Gaps = 4/104 (3%)
 Frame = -3

Query: 69   RFRTITTAYYRGAMGIMLVYDITNEKSFDNIRNWIRNIEEHASADVEKMILGNKCDV--- 125
            R+  ++  YYRGA   +L +D+T++ SFD IR WI  + +H   + +  I G K D+   
Sbjct: 1049 RYEAMSRIYYRGAKAAILCFDLTDKSSFDRIRFWIGELRQH-EEECKLYICGTKFDLVHD 873

Query: 126  -NDKRQVSKERGEKLALDYGIKFMETSAKANINVENAFFTLARD 168
              ++R V +   + LA D   +  ETS+    N+E  F  +A D
Sbjct: 872  DPERRAVPRSVAKALADDCMAEIYETSSMTGDNIEKLFTKIAED 741
>09827
          Length = 1201

 Score = 55.1 bits (131), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 38/139 (27%), Positives = 68/139 (48%), Gaps = 1/139 (0%)
 Frame = -3

Query: 9    FKLLLIGDSGVGKTCVLFRFSEDAFNSTFISTIGIDFKIRTIELDGKRIKLQIWDTAGQE 68
             ++L++G    GKT +L++       +T I TIG  F + T+E   K I   +WD  GQ+
Sbjct: 1112 MRILMVGLDAAGKTTILYKLKLGEIVTT-IPTIG--FNVETVEY--KNISFTVWDVGGQD 948

Query: 69   RFRTITTAYYRGAMGIMLVYDITNEKSFDNIRNWI-RNIEEHASADVEKMILGNKCDVND 127
            + R +   Y++   G++ V D  +++     R  + R + E    D   ++  NK D+  
Sbjct: 947  KIRPLWRHYFQNTQGLIFVVDSNDKERVQEAREELTRMLNEDELRDAVLLVFANKQDL-P 771

Query: 128  KRQVSKERGEKLALDYGIK 146
                + E  EKL L +G++
Sbjct: 770  HAMATAEITEKLGL-HGLR 717
>08153
          Length = 1703

 Score = 51.6 bits (122), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 32/125 (25%), Positives = 61/125 (48%), Gaps = 1/125 (0%)
 Frame = +1

Query: 10  KLLLIGDSGVGKTCVLFRFSEDAFNSTFISTIGIDFKIRTIELDGKRIKLQIWDTAGQER 69
           ++L++G    GKT +L++       +T I TIG  F + T+E   K I   +WD  GQ++
Sbjct: 88  RILMVGLDAAGKTTILYKLKLGEIVTT-IPTIG--FNVETVEY--KNISFTVWDVGGQDK 252

Query: 70  FRTITTAYYRGAMGIMLVYDITNEKSFDNIRNWI-RNIEEHASADVEKMILGNKCDVNDK 128
            R +   Y++   G++ V D  + +  +  +  + R + E    D   ++  NK D+ + 
Sbjct: 253 IRPLWRHYFQNTQGLIFVVDSNDRERINEAKEELARMLNEDDLRDAIILVFANKQDLPNA 432

Query: 129 RQVSK 133
              S+
Sbjct: 433 YSASE 447
>14775
          Length = 380

 Score = 50.1 bits (118), Expect = 7e-07,   Method: Compositional matrix adjust.
 Identities = 36/147 (24%), Positives = 58/147 (39%), Gaps = 1/147 (0%)
 Frame = -2

Query: 21  KTCVLFRFSEDAFNSTFISTIGIDF-KIRTIELDGKRIKLQIWDTAGQERFRTITTAYYR 79
           KTC+L R+ +  F    + TI +   +      D   ++  +WDT G E +R++  +++R
Sbjct: 379 KTCLLRRYQKGFFMDRTMPTIAVLCSEFNESRTDPLNVRYTLWDTGGAETYRSLWVSHFR 200

Query: 80  GAMGIMLVYDITNEKSFDNIRNWIRNIEEHASADVEKMILGNKCDVNDKRQVSKERGEKL 139
           GA   +LVYD+T                                          ERG+  
Sbjct: 199 GAQVALLVYDVTC-----------------------------------------ERGQAF 143

Query: 140 ALDYGIKFMETSAKANINVENAFFTLA 166
           A   G  F ETS+    NV+  F+ +A
Sbjct: 142 ATQCGYTFFETSSVTGKNVDAVFWEIA 62
>29380
          Length = 853

 Score = 49.7 bits (117), Expect = 9e-07,   Method: Compositional matrix adjust.
 Identities = 32/116 (27%), Positives = 54/116 (46%), Gaps = 6/116 (5%)
 Frame = -2

Query: 81  AMGIMLVYDITNEKSFDNIRNWIRNIEEHASADVEKMILGNKCDV-NDKRQVSKERGEKL 139
           A   ++VYD+    +F     W++ + +  +  V  ++ GNK D+    R VS E  +  
Sbjct: 852 ASAAIIVYDVNIADTFSRALAWVKELRQQNTESVLIILAGNKVDLATQHRAVSFEDAQSF 673

Query: 140 ALDYGIKFMETSAKANINVENAFFTLA-----RDIKAKMDKKLEGNSPQGSSHGVK 190
           A + G+ F E SAK  + V   F TLA     ++I    ++ +  N   G + G K
Sbjct: 672 ARENGLLFAEVSAKTGMAVNEIFMTLANQLIQQEIDGSRNRGVTLNRENGEASGCK 505
>00552
          Length = 455

 Score = 48.5 bits (114), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 18/42 (42%), Positives = 29/42 (69%)
 Frame = -3

Query: 61  IWDTAGQERFRTITTAYYRGAMGIMLVYDITNEKSFDNIRNW 102
           IWDTAGQER++++ T +YRG    +L + + N KS  ++ +W
Sbjct: 147 IWDTAGQERYKSLRTPFYRGTDCCLLTFSVDNLKSLQSLSDW 22

 Score = 44.7 bits (104), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 19/53 (35%), Positives = 35/53 (66%)
 Frame = -1

Query: 8   LFKLLLIGDSGVGKTCVLFRFSEDAFNSTFISTIGIDFKIRTIELDGKRIKLQ 60
           L K++L+GD GVGK+ ++ RF  + F++    TIG++F  + + +DG+   +Q
Sbjct: 446 LLKVVLLGDGGVGKSSLMNRFVSNKFDAQSFHTIGVEFLTKDVVVDGETFTMQ 288
>31291
          Length = 446

 Score = 48.5 bits (114), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 34/118 (28%), Positives = 53/118 (44%), Gaps = 14/118 (11%)
 Frame = -1

Query: 59  LQIWDTAGQERFRTITTAYYRGAMGIMLVYDITNEKSFDNIR-NWIRNIEEHASADVEKM 117
           LQ+WDTAGQE +  +    Y      ML + + +E S  N++  W   I  H    V  +
Sbjct: 446 LQLWDTAGQEDYDRLRPLAYPNTDVFMLXFSLMSEASMKNVKVKWYPEIRHH-DPHVPIV 270

Query: 118 ILGNKCDVNDKRQ------------VSKERGEKLALDYGIK-FMETSAKANINVENAF 162
           ++G K D+   ++            VS  +G  LA     K + E S+K   N++ AF
Sbjct: 269 LVGTKLDLRQDKEAVRKLRSSRQDPVSSNQGNDLAKAIKAKRYFECSSKTQENLKTAF 96
>18509
          Length = 625

 Score = 48.1 bits (113), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 24/64 (37%), Positives = 42/64 (65%)
 Frame = -3

Query: 113 DVEKMILGNKCDVNDKRQVSKERGEKLALDYGIKFMETSAKANINVENAFFTLARDIKAK 172
           +V  +++GNK D+   R V + +G+ +A  Y I ++ETSAK    V++AF+TL R+I+  
Sbjct: 530 EVPMVLVGNKVDL-PIRNVEQRQGKHMAELYHIPYVETSAKTRQGVDDAFYTLVREIRKY 354

Query: 173 MDKK 176
            ++K
Sbjct: 353 KERK 342
>10862
          Length = 2896

 Score = 45.8 bits (107), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 32/127 (25%), Positives = 52/127 (40%), Gaps = 1/127 (0%)
 Frame = -3

Query: 16   DSGVGKTCVLFRFSEDAFNSTFISTIGIDFKIRTIELDGKRIKLQIWDTAGQERFRTITT 75
            D  VG  C    +S     +  +     + +I+      +  +  +WD  GQ++ R +  
Sbjct: 2609 DPHVGA*CCRENYSSIQNETRTVCDXNTNSRIQCRNCQLQECQFNVWDVGGQDKIRPLWR 2430

Query: 76   AYYRGAMGIMLVYDITNEKSFDNIRNWI-RNIEEHASADVEKMILGNKCDVNDKRQVSKE 134
             YY G  G++ V D  +    D  R  + R I +    D   +I  NK D+ D  +   E
Sbjct: 2429 HYYTGTQGLIFVVDCADRDRIDEARQELHRIINDREMRDAIILIFANKQDLPDAMK-PHE 2253

Query: 135  RGEKLAL 141
              EKL L
Sbjct: 2252 IQEKLGL 2232
>33605
          Length = 888

 Score = 45.4 bits (106), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 27/80 (33%), Positives = 44/80 (55%)
 Frame = +1

Query: 10  KLLLIGDSGVGKTCVLFRFSEDAFNSTFISTIGIDFKIRTIELDGKRIKLQIWDTAGQER 69
           +LL++G    GKT +L +F+ +  + T   T+G  F I+T+E  G   KL +WD  GQ+ 
Sbjct: 502 RLLMLGLDNAGKTTILKKFNGEDID-TISPTLG--FNIKTLEHRG--FKLNVWDVGGQQS 666

Query: 70  FRTITTAYYRGAMGIMLVYD 89
            R+    Y+    G++ V D
Sbjct: 667 LRSYWRNYFESTDGLVWVVD 726
>25796
          Length = 422

 Score = 45.1 bits (105), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 17/28 (60%), Positives = 23/28 (82%)
 Frame = -1

Query: 1  MAKTYDYLFKLLLIGDSGVGKTCVLFRF 28
          M++TYDYLFK L+IG +G GK+C+L  F
Sbjct: 89 MSETYDYLFKFLIIGSAGSGKSCLLHHF 6
>12443
          Length = 837

 Score = 43.9 bits (102), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 37/137 (27%), Positives = 67/137 (48%), Gaps = 9/137 (6%)
 Frame = -3

Query: 9   FKLLLIGDSGVGKTCVLFRFSEDAFNSTFISTIGID----FKIRTIELDGKRI--KLQIW 62
           +K++L+G +GVGKT  + + + +    T   T G+     +    I+  GK +  ++Q++
Sbjct: 580 YKVMLVGKTGVGKTSTVAKLTGNDIPLTHNETPGLQTSHLYWPGKIKHLGKTVLFQIQLF 401

Query: 63  DTAGQ---ERFRTITTAYYRGAMGIMLVYDITNEKSFDNIRNWIRNIEEHASADVEKMIL 119
           D AG+   +R+  I  A   G  GIM ++   ++ SFD I   +          + K+ L
Sbjct: 400 D-AGETALKRYDHILPACQDGVDGIMFLFSFVDKGSFDEIPQLLTRFTT-LEDGICKIAL 227

Query: 120 GNKCDVNDKRQVSKERG 136
           G K     K  ++K+RG
Sbjct: 226 GTKYPFPHKGIINKDRG 176
>14119
          Length = 602

 Score = 42.0 bits (97), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 22/76 (28%), Positives = 39/76 (51%), Gaps = 1/76 (1%)
 Frame = +1

Query: 95  SFDNIRNWIRNIEEHASADVEKMILGNKCDV-NDKRQVSKERGEKLALDYGIKFMETSAK 153
           +F+    W++ + +  +  V  ++ GNK D+ ++ R VS +     A D G+ F E SAK
Sbjct: 1   TFNRALAWVKELRQQNAGSVLIVLAGNKADLASEHRAVSADDARTFAEDNGLIFAEVSAK 180

Query: 154 ANINVENAFFTLARDI 169
             + V   F T+A  +
Sbjct: 181 TGMAVSEVFMTIAHKL 228
>10708
          Length = 2775

 Score = 35.8 bits (81), Expect = 0.011,   Method: Compositional matrix adjust.
 Identities = 14/45 (31%), Positives = 26/45 (57%)
 Frame = -2

Query: 55   KRIKLQIWDTAGQERFRTITTAYYRGAMGIMLVYDITNEKSFDNI 99
            ++++L +WDTAGQE +  +    Y     I++ + I +  S +NI
Sbjct: 2729 QQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENI 2595
>18184
          Length = 558

 Score = 30.8 bits (68), Expect = 0.39,   Method: Compositional matrix adjust.
 Identities = 14/36 (38%), Positives = 22/36 (61%)
 Frame = -3

Query: 7   YLFKLLLIGDSGVGKTCVLFRFSEDAFNSTFISTIG 42
           YLF +LL G    G  C++  F  ++F + F+ST+G
Sbjct: 442 YLFYILLTGIVQFGYCCLVGTFPFNSFLAGFVSTVG 335
>02923
          Length = 569

 Score = 30.0 bits (66), Expect = 0.67,   Method: Compositional matrix adjust.
 Identities = 21/79 (26%), Positives = 40/79 (50%), Gaps = 3/79 (3%)
 Frame = +2

Query: 58  KLQIWDTAGQ---ERFRTITTAYYRGAMGIMLVYDITNEKSFDNIRNWIRNIEEHASADV 114
           ++Q++D AG+   +R+  I  A   G  GIM ++   ++ SFD I   +          +
Sbjct: 35  QIQLFD-AGETALKRYDHILPACQDGVDGIMFLFSFVDKGSFDEIPQLLTRFTTLEDG-I 208

Query: 115 EKMILGNKCDVNDKRQVSK 133
            K+ LG K D++   +V++
Sbjct: 209 CKIALGTKFDLHAHSEVTQ 265
>18949
          Length = 414

 Score = 28.1 bits (61), Expect = 2.6,   Method: Compositional matrix adjust.
 Identities = 14/64 (21%), Positives = 31/64 (48%), Gaps = 1/64 (1%)
 Frame = +3

Query: 62  WDTAGQERFRTITTAYYRGAMGIMLVYDITNEKSFDNIRNWIRNI-EEHASADVEKMILG 120
           +D  G  + R +   Y+    GI+ + D+ + +     +  + ++  +   AD+  ++LG
Sbjct: 72  FDLGGHRQARRVWKDYFPAVDGIVFIVDVHDTERITEAKAELDSLLRDDQIADIPVLVLG 251

Query: 121 NKCD 124
           NK D
Sbjct: 252 NKMD 263
>31593
          Length = 646

 Score = 27.7 bits (60), Expect = 3.2,   Method: Compositional matrix adjust.
 Identities = 11/26 (42%), Positives = 17/26 (65%)
 Frame = -3

Query: 109 HASADVEKMILGNKCDVNDKRQVSKE 134
           HA+ +VE + + N C+ ND  QV +E
Sbjct: 545 HATWEVESVFVSNLCNCNDLIQVVRE 468
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|149263317|ref|XP_922176.3| PREDICTED: synaptic
nuclear envelope 2 [Mus musculus]
         (6898 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

19002                                                                 148   9e-35
05733                                                                  73   3e-12
19147                                                                  73   4e-12
29446                                                                  70   3e-11
17613                                                                  51   5e-11
09100                                                                  65   8e-10
34417                                                                  61   1e-08
18556                                                                  39   0.085
09711                                                                  39   0.087
32371                                                                  37   0.25 
32088                                                                  35   1.0  
04951                                                                  32   6.5  
>19002
          Length = 842

 Score =  148 bits (373), Expect = 9e-35,   Method: Compositional matrix adjust.
 Identities = 90/238 (37%), Positives = 124/238 (52%), Gaps = 1/238 (0%)
 Frame = -2

Query: 64  GHVLLDLLEV-LSGQQLPRDKGSNTFQCRINIEHALTFLKNRSIKLINIHVADIVEGNPS 122
           G +L+ LLEV + G+     KG     C  N++ ALTFL  + + L N+   DIV+G+  
Sbjct: 838 GKMLMKLLEVRVRGEIASDXKGKMRIHCLENVDKALTFLHEQRVHLENMGAHDIVDGSSR 659

Query: 123 IILGLIWTIILHFHIEKLAQTLSCDYNQXXXXXXXXXXXXXXXXXXXXXXXXXQAQARWQ 182
           + LGLIWTIIL F I+ +                                    ++ +  
Sbjct: 658 LTLGLIWTIILRFQIQDI-----------------------------MIEEVDNSETK-- 572

Query: 183 WSAKKALLQWAQEQCARSESVNVTDFKSSWRNGMAFLAVIHALRPDLIDMDSMRHRSNKD 242
            SAK ALL W Q + A   +VNV +F +SWR+G+AF A+IH  RPDL+  D +   S   
Sbjct: 571 -SAKDALLLWCQMKTAGYPNVNVRNFTTSWRDGLAFNAIIHKHRPDLVQYDRLHKSSAIQ 395

Query: 243 NLKEAFRIAEHELKIPKLLEPEDVDVVNPDEKSIMTYVAQFLKYSKDAPGPGDSTQAK 300
           NL+ AF +AE +L +  LLEPEDV+V  PDEKSI+TYV  +  Y   +    DS Q K
Sbjct: 394 NLQNAFTVAEDKLGLTALLEPEDVNVEYPDEKSIITYVVTYYHYF--SKMKADSVQGK 227
>05733
          Length = 1021

 Score = 73.2 bits (178), Expect = 3e-12,   Method: Compositional matrix adjust.
 Identities = 40/109 (36%), Positives = 61/109 (55%), Gaps = 3/109 (2%)
 Frame = +2

Query: 188 ALLQWAQE--QCARSESVNVTDFKSSWRNGMAFLAVIHALRPDLIDMDSMRHRSNKDNLK 245
           +LL+W Q          V++ DF SSWR+G+AF A+IHA RP LI   S+       N +
Sbjct: 467 SLLRWCQRVLNXGTYRGVHIIDFTSSWRSGLAFCALIHAFRPHLISPASLMECETVKNNQ 646

Query: 246 EAFRIAEHELKIPKLLEPEDVDVVN-PDEKSIMTYVAQFLKYSKDAPGP 293
            AF +A+ EL I  ++  ED+     PD+ +++ Y++QF +  K  P P
Sbjct: 647 LAFDVAQKELGIAPVMRGEDMAACAVPDKLTMVAYLSQFHELFKHEPLP 793
>19147
          Length = 474

 Score = 72.8 bits (177), Expect = 4e-12,   Method: Composition-based stats.
 Identities = 41/137 (29%), Positives = 69/137 (50%)
 Frame = +1

Query: 99  TFLKNRSIKLINIHVADIVEGNPSIILGLIWTIILHFHIEKLAQTLSCDYNQXXXXXXXX 158
           +++ ++ +KL++I   +IV+GN  + LG+IWTIIL F I+ +                  
Sbjct: 46  SYIASKGVKLVSIGAEEIVDGNVKMTLGMIWTIILRFAIQDITVE--------------- 180

Query: 159 XXXXXXXXXXXXXXXXXQAQARWQWSAKKALLQWAQEQCARSESVNVTDFKSSWRNGMAF 218
                                  + +AK+ LL W Q + A  ++VNV +F  S+++G+AF
Sbjct: 181 -----------------------ELTAKEGLLLWCQRKTAPYKNVNVQNFHLSFKDGLAF 291

Query: 219 LAVIHALRPDLIDMDSM 235
            A+IH  RP+LID  S+
Sbjct: 292 CALIHRHRPELIDYHSL 342
>29446
          Length = 1445

 Score = 70.1 bits (170), Expect = 3e-11,   Method: Compositional matrix adjust.
 Identities = 43/114 (37%), Positives = 64/114 (56%), Gaps = 3/114 (2%)
 Frame = +3

Query: 27   AEQEDTQKKTFTCWINSQLAKHTPPSVVSDLFADIKKGHVLLDLLEVLSGQQLPRDKGSN 86
            A+ +  QK TFT W N  L   T    ++DL +D   G  L+ L+EVLSG++        
Sbjct: 984  AQWKIIQKNTFTRWANEHL--RTVNKAIADLESDFSDGLRLVALIEVLSGKKFKHVNKRP 1157

Query: 87   TFQCRI--NIEHALTFLKN-RSIKLINIHVADIVEGNPSIILGLIWTIILHFHI 137
             F+ +   N+   L FL++   I+++NI   DIV+    +ILGLIWT+ILH+ I
Sbjct: 1158 NFRTQKLENVTLTLKFLEDDEGIRIVNIDSTDIVDKKLKLILGLIWTLILHYSI 1319
>17613
          Length = 1108

 Score = 51.2 bits (121), Expect(2) = 5e-11,   Method: Composition-based stats.
 Identities = 26/63 (41%), Positives = 40/63 (63%)
 Frame = +1

Query: 196 QCARSESVNVTDFKSSWRNGMAFLAVIHALRPDLIDMDSMRHRSNKDNLKEAFRIAEHEL 255
           + A  ++VNV +F  S+++G+AF A+IH  RP+LID  S+   +  +NL  AF IAE+  
Sbjct: 220 KTAPYKNVNVQNFHLSFKDGLAFCALIHRHRPELIDYHSLSKDNPLENLNTAFDIAENTW 399

Query: 256 KIP 258
             P
Sbjct: 400 TSP 408

 Score = 38.1 bits (87), Expect(2) = 5e-11,   Method: Compositional matrix adjust.
 Identities = 15/31 (48%), Positives = 23/31 (74%), Gaps = 1/31 (3%)
 Frame = +3

Query: 255 LKIPKLLEPED-VDVVNPDEKSIMTYVAQFL 284
           L IP++L+PED V+   PDE+S+M YV+ + 
Sbjct: 396 LDIPRMLDPEDMVNSAKPDERSVMAYVSSYY 488

 Score = 41.6 bits (96), Expect = 0.012,   Method: Composition-based stats.
 Identities = 17/38 (44%), Positives = 28/38 (73%)
 Frame = +2

Query: 103 NRSIKLINIHVADIVEGNPSIILGLIWTIILHFHIEKL 140
           ++ +KL++I   +IV+GN  + LG+IWTIIL F I+ +
Sbjct: 56  SKGVKLVSIGAEEIVDGNVKMTLGMIWTIILRFAIQDI 169
>09100
          Length = 930

 Score = 65.1 bits (157), Expect = 8e-10,   Method: Compositional matrix adjust.
 Identities = 35/105 (33%), Positives = 55/105 (52%), Gaps = 2/105 (1%)
 Frame = +1

Query: 33  QKKTFTCWINSQLAKHTPPSVVSDLFADIKKGHVLLDLLEVLSGQQLPRDKGSNTF--QC 90
           Q   +  WINSQL K     ++ DL  D++ G V  D++ ++S QQ+P  +   T   + 
Sbjct: 463 QLSAYMAWINSQLKKKPGAHLIEDLRHDMRDGVVFADVIHIVSKQQIPGIQNVPTTLDEM 642

Query: 91  RINIEHALTFLKNRSIKLINIHVADIVEGNPSIILGLIWTIILHF 135
           R N++  L F+    IK+  I   DIVEGN   ++ LI  +  H+
Sbjct: 643 RQNVDRVLHFMTQNRIKMHRISSRDIVEGNLKAVMRLILALAAHY 777
>34417
          Length = 1096

 Score = 61.2 bits (147), Expect = 1e-08,   Method: Composition-based stats.
 Identities = 31/83 (37%), Positives = 46/83 (55%), Gaps = 1/83 (1%)
 Frame = +2

Query: 208 FKSSWRNGMAFLAVIHALRPDLIDMDSMRHRSNKDNLKEAFRIAEHELKIPKLLEPED-V 266
             S W NG+AF A+IH   PD  D   ++ ++ + N + AF  AE    I  LL+ ED +
Sbjct: 35  LSSCWNNGLAFCALIHHFYPDAFDYSQLQPQNRRYNFELAFDTAEKLADISPLLDVEDMI 214

Query: 267 DVVNPDEKSIMTYVAQFLKYSKD 289
            + NPD K + TYV  F ++ +D
Sbjct: 215 KMKNPDWKCVFTYVQSFYRHLRD 283
>18556
          Length = 799

 Score = 38.5 bits (88), Expect = 0.085,   Method: Compositional matrix adjust.
 Identities = 26/98 (26%), Positives = 50/98 (51%), Gaps = 2/98 (2%)
 Frame = +2

Query: 188 ALLQWAQEQCARSE-SVNVTDFKSSWRNGMAFLAVIHALRPDLIDMDSMRHRSNKDNLKE 246
           +LL+W   Q A  + +  + +    +RNG    A+I   RPDLID  + +  S  +  + 
Sbjct: 44  SLLRWISVQLAAYQFTAELKEPSDVFRNGRVLCALISRFRPDLIDYAATKDMSPLECNEL 223

Query: 247 AFRIAEHELKIPKLLEP-EDVDVVNPDEKSIMTYVAQF 283
           AF + E EL I +++   + +D+ + + +  + Y+ Q 
Sbjct: 224 AFAVLERELHIDRIMSAKQSLDLNDVESRVWLNYMDQI 337
>09711
          Length = 3041

 Score = 38.5 bits (88), Expect = 0.087,   Method: Compositional matrix adjust.
 Identities = 34/133 (25%), Positives = 61/133 (45%), Gaps = 16/133 (12%)
 Frame = +1

Query: 26  QAEQEDTQK------KTFTCWINSQLAKHTPPSVVSDLFADIKKGHVLLDLLEVL----- 74
           Q E ED  K      KT+  W+NS          V  L++D+  G ++  L + +     
Sbjct: 811 QVEVEDVMKEESREEKTYRNWMNSLGVS----PFVHHLYSDLYDGLIIFQLYDYIQPGLV 978

Query: 75  --SGQQLPRDKGSNTFQCRINIEHALTF---LKNRSIKLINIHVADIVEGNPSIILGLIW 129
             S  +   +K    F+   N  +A+     +K   +KL+ I   DI++GNP + LGL+W
Sbjct: 979 DWSKVKKKFNKLKARFERIENCNYAVELGPQVKLVKVKLVGIAGQDILDGNPVLTLGLVW 1158

Query: 130 TIILHFHIEKLAQ 142
            ++  + +  L++
Sbjct: 1159QLMRAYTLAILSK 1197

 Score = 32.0 bits (71), Expect = 9.1,   Method: Compositional matrix adjust.
 Identities = 32/120 (26%), Positives = 52/120 (43%), Gaps = 20/120 (16%)
 Frame = +1

Query: 33  QKKTFTCWINSQLA-----KHTPP--SVVSDLFADIKKGHVLLDLLEVLSGQQLPRDKGS 85
           ++K F  WIN  L+     KH  P  +  + LF  +  G +L  L+             S
Sbjct: 52  EQKAFAEWINRHLSDXPDCKHLLPLDADGTQLFGQMADGVLLCKLIN---------HSVS 204

Query: 86  NTFQCR-INIEHALTFLKNRSIKL------------INIHVADIVEGNPSIILGLIWTII 132
           NT   R IN ++   + ++ ++ L            +NI   D+  G P ++LGL+W II
Sbjct: 205 NTIDERTINKQNLSLYRRHENLTLAVNSAGAIGCTTVNIGPEDLAAGRPHLVLGLLWQII 384
>32371
          Length = 625

 Score = 37.0 bits (84), Expect = 0.25,   Method: Composition-based stats.
 Identities = 14/25 (56%), Positives = 18/25 (72%)
 Frame = -1

Query: 202 SVNVTDFKSSWRNGMAFLAVIHALR 226
           SV++ D   SWRNG+AF A+IH  R
Sbjct: 625 SVDIKDLLVSWRNGLAFCAIIHRFR 551
>32088
          Length = 1928

 Score = 35.0 bits (79), Expect = 1.0,   Method: Composition-based stats.
 Identities = 29/114 (25%), Positives = 45/114 (39%), Gaps = 11/114 (9%)
 Frame = +1

Query: 30   EDTQKKTFTCWINSQL-----AKHTPP--SVVSDLFADIKKGHVLLDLLEVLSGQQLPR- 81
            +D ++K F  WIN  L      KH         DLF  +  G +L  L+       +   
Sbjct: 1255 KDGEQKAFAAWINRHLKDDPDCKHLMEVNEEGDDLFKKVGDGILLCKLINHSVSNTIDER 1434

Query: 82   ---DKGSNTFQCRINIEHALTFLKNRSIKLINIHVADIVEGNPSIILGLIWTII 132
                   N +    N+  A+    +     +NI   D+  G P ++LGL+W II
Sbjct: 1435 AINKSNLNVYHRHENLTLAVNSAGSIGCTTVNIGPEDLAAGRPHLVLGLLWQII 1596
>04951
          Length = 2852

 Score = 32.3 bits (72), Expect = 6.5,   Method: Composition-based stats.
 Identities = 17/53 (32%), Positives = 31/53 (58%), Gaps = 3/53 (5%)
 Frame = +1

Query: 93  NIEHALTF---LKNRSIKLINIHVADIVEGNPSIILGLIWTIILHFHIEKLAQ 142
           N E+A+     +K   +KL+ I   DI +GNP + LGL+W ++  + +  L++
Sbjct: 13  NCEYAVQLGPQMKVCKMKLVGIGGKDIHDGNPVLTLGLVWQLMRAYTLAILSK 171
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|56699434|ref|NP_001005331.1| eukaryotic translation
initiation factor 4, gamma 1 isoform b [Mus musculus]
         (1593 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

11597                                                                 145   9e-35
30336                                                                  65   4e-16
14839                                                                  45   3e-04
16157                                                                  42   0.002
19285                                                                  38   0.028
02428                                                                  32   2.3  
>11597
          Length = 2290

 Score =  145 bits (367), Expect = 9e-35,   Method: Compositional matrix adjust.
 Identities = 101/394 (25%), Positives = 177/394 (44%), Gaps = 5/394 (1%)
 Frame = +2

Query: 1201 KAASLTEDRGRDPVKREATLPPVSPPKAALSVDEVEKKSKAIIEEYLHLNDMKEAVQCVQ 1260
            + AS    R RD     A         + L+  E++++   I EE+    + K+A + + 
Sbjct: 830  RNASRDNSRSRDMPPPAAPAQASGIDVSQLNAGEIDRRINTIAEEFHSNQNFKDARESIA 1009

Query: 1261 ELASPSLLFIFVRLGIESTLERSTIAREHMGRLLHQLLCAGHLSTAQYYQGLYETLELAE 1320
            EL+      +   L +E  +E++   R  +G+LL  ++   +L T    +G+ E L+ AE
Sbjct: 1010 ELSGLDKSLLVTTL-LEKLVEKAGKTRRLLGQLLFDMVADKYLPTDNLIKGIAEFLQFAE 1186

Query: 1321 DMEIDIPHVWLYLAELITPILQEDGVPMGELFREITKPLRPMGKATSLLL--EILGLLCK 1378
            D+E+DIP +W  +AE+   ++ ++ V      +   +PL   G     L   +IL     
Sbjct: 1187 DLELDIPKIWDNMAEVFASLVADNQVLPLSFLQASLQPLVDQGNKKEALFMPKILNKASD 1366

Query: 1379 SMGPKKVGMLWREAGLSWREF-LAEGQ-DVGSFVAEKKVEYTLGEESEAPGQRTLAFXXX 1436
                 +V   W  +GL   +F ++EG  D+       +     G +S             
Sbjct: 1367 YKSKDEVQAQWAASGLKLSDFGISEGHPDLQWLKGPARNMVREGVQSR------------ 1510

Query: 1437 XXXXXXXXXDGGSNQRVFDWIDANLNEQQIASNTLVRALMTTVCYSAIIFETPLRVDVQV 1496
                     +  SN+ VF WID N N+++   N  VR L+  VC S+I  +   ++D   
Sbjct: 1511 -------LRNNASNEEVFRWIDGNFNKEETQGNKFVRELVAAVCASSI--DASKKLDEAA 1663

Query: 1497 LKVRARLLQKYLCDEQKEXXXXXXXXXXXXXXEQPANLLRMFFDALYDEDVVKEDAFYSW 1556
            ++ R  +L+KY+ +++                + P +L R  F+ LYDEDV+ ED+++ W
Sbjct: 1664 MRNRLPVLRKYMLNQENGTQALFSIQHLLCELQHPKDLGRDLFELLYDEDVISEDSYFDW 1843

Query: 1557 ESSKDPAEQ-QGKGVALKSVTAFFNWLREAEDEE 1589
            E    P E   GKG    ++  FF+WLR   +E+
Sbjct: 1844 ERRDGPKEDMSGKGAVKMNLKNFFDWLRSGGEED 1945

 Score = 80.9 bits (198), Expect = 4e-15,   Method: Compositional matrix adjust.
 Identities = 54/165 (32%), Positives = 81/165 (49%), Gaps = 21/165 (12%)
 Frame = +2

Query: 933  CRLLTTIGKDLDFAKAKPRMDQYFNQMEKIIKE-------------------KKTSSRIR 973
             +LL TIG +LD  KAK RMDQYF Q+EK+  +                    K S+R++
Sbjct: 2    TKLLDTIGGELDHPKAKTRMDQYFQQLEKMTSDLTAAQQSATGHMPKSKDPKDKLSTRVK 181

Query: 974  FMLQDVLDLRQSNWVPRR--GDQGPKTIDQIHKEAEMEEHREHIKVQQLMAKGSDKXXXX 1031
            F + D+++LR++ WV RR      P T+ +IH++A+ E+        Q  ++        
Sbjct: 182  FGILDIIELRRNRWVKRRIHAQNMPTTLTEIHQKAKQEQQEAQFLSSQPRSEPQGARSSR 361

Query: 1032 XXXXXXXXXLPLVDDGGWNTVPISKGSRPIDTSRLTKITKPGSID 1076
                      P   D GWNTVP  +  + ID +R+ KITK  S+D
Sbjct: 362  GGGASGGKGRPGQGDDGWNTVPARQVKQQIDAARM-KITKT-SVD 490
>30336
          Length = 388

 Score = 65.5 bits (158), Expect(2) = 4e-16,   Method: Composition-based stats.
 Identities = 35/73 (47%), Positives = 46/73 (63%), Gaps = 2/73 (2%)
 Frame = -3

Query: 936  LTTIGKDLDFAKAKPRMDQYFNQMEKIIKEKKTSSRIRFMLQDVLDLRQSNWVPRR--GD 993
            + T+G  LD  KAK  M QYF ++E     +  + RIRFMLQDV++LR + W PRR   +
Sbjct: 260  IRTVGPRLDTPKAKALMKQYFVRIEVFAVNEDLTPRIRFMLQDVIELRANEWKPRRVATE 81

Query: 994  QGPKTIDQIHKEA 1006
             GPKTI  I +EA
Sbjct: 80   NGPKTITAIRQEA 42

 Score = 39.3 bits (90), Expect(2) = 4e-16,   Method: Composition-based stats.
 Identities = 19/43 (44%), Positives = 26/43 (60%), Gaps = 7/43 (16%)
 Frame = -1

Query: 900 GELFKLKMLTEAIMHDCVVKLLKNHD-------EESLECLCRL 935
           GEL KL ML E I+H C+ +LL+          EE +ECLC++
Sbjct: 388 GELGKLDMLYEGILHKCIQQLLEKKKNTPLRDMEEDMECLCQI 260
>14839
          Length = 340

 Score = 44.7 bits (104), Expect = 3e-04,   Method: Composition-based stats.
 Identities = 22/56 (39%), Positives = 33/56 (58%)
 Frame = +3

Query: 1531 PANLLRMFFDALYDEDVVKEDAFYSWESSKDPAEQQGKGVALKSVTAFFNWLREAE 1586
            P  +L  FF  LYD+++++E+AF  W+   +  E  GKG AL  V  +  WL +AE
Sbjct: 66   PKGMLLRFFVNLYDQEIIEEEAFLHWKEEVND-EFPGKGKALFQVNQWLTWLEQAE 230
>16157
          Length = 1330

 Score = 42.0 bits (97), Expect = 0.002,   Method: Composition-based stats.
 Identities = 21/56 (37%), Positives = 32/56 (57%)
 Frame = -1

Query: 1531 PANLLRMFFDALYDEDVVKEDAFYSWESSKDPAEQQGKGVALKSVTAFFNWLREAE 1586
            P  +L  FF  LYD+++++E+AF  W+   +  E  GKG  L  V  +  WL +AE
Sbjct: 796  PKGMLLRFFVNLYDQEIIEEEAFLHWKEEVND-EFPGKGKXLFQVNQWLTWLEQAE 632
>19285
          Length = 396

 Score = 38.1 bits (87), Expect = 0.028,   Method: Composition-based stats.
 Identities = 28/108 (25%), Positives = 50/108 (46%), Gaps = 18/108 (16%)
 Frame = +1

Query: 898 FIGELF------------KLKMLTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGKDLDF 945
           F+GELF            +L  L  A+  D V+ LL +  + S++  C+LL   G   + 
Sbjct: 37  FMGELFLNVTADSSGQTERLHFLPTALT-DLVLTLLSHPSDLSVKTACQLLKMAGGHTED 213

Query: 946 AKAKPRMDQ------YFNQMEKIIKEKKTSSRIRFMLQDVLDLRQSNW 987
           A  +    +       F+ ++ +      S  ++ +++ VLDLRQ+NW
Sbjct: 214 AMCQKETHEQQNFHSIFSSLQNLQNAPHISQNMKLLMKSVLDLRQNNW 357
>02428
          Length = 979

 Score = 32.0 bits (71), Expect = 2.3,   Method: Composition-based stats.
 Identities = 14/35 (40%), Positives = 23/35 (65%)
 Frame = -1

Query: 1230 LSVDEVEKKSKAIIEEYLHLNDMKEAVQCVQELAS 1264
            LSVD VE     I + Y++LN +K A++C+ E+ +
Sbjct: 424  LSVDCVETVKLCIWDVYIYLNQIKTAIKCLTEMCA 320
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|114326446|ref|NP_071855.2| myosin, heavy polypeptide
9, non-muscle isoform 1 [Mus musculus]
         (1960 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

25944                                                                 146   1e-34
25922                                                                 103   8e-22
01284                                                                  92   2e-18
31878                                                                  64   2e-16
01074                                                                  72   2e-12
33963                                                                  48   5e-05
30605                                                                  35   0.26 
>25944
          Length = 417

 Score =  146 bits (368), Expect = 1e-34,   Method: Compositional matrix adjust.
 Identities = 77/137 (56%), Positives = 111/137 (81%)
 Frame = -3

Query: 1541 LEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELED 1600
            +EELEDELQA ED KLRLEVN+ A++ +++ ++ GR+EQ EE K+ L+RQ+REMEAELED
Sbjct: 415  IEELEDELQAAEDGKLRLEVNMNALREKYKNEVAGREEQEEESKRSLLRQLREMEAELED 236

Query: 1601 ERKQRSMAMAARKKLEMDLKDLEAHIDTANKNREEAIKQLRKLQAQMKDCMRELDDTRAS 1660
            ERKQR++A+ AR KL+ D++ +E  ++ A K +E+A+KQ +K+ AQMKD   EL+D R +
Sbjct: 235  ERKQRALAVNARNKLQGDVQGMEQQLEMATKVKEDAVKQYKKIFAQMKDFQHELEDARIA 56

Query: 1661 REEILAQAKENEKKLKS 1677
            RE++ AQAK+NEKK+K+
Sbjct: 55   REDMAAQAKDNEKKVKN 5
>25922
          Length = 422

 Score =  103 bits (256), Expect = 8e-22,   Method: Composition-based stats.
 Identities = 57/124 (45%), Positives = 76/124 (61%)
 Frame = -2

Query: 394 IKVGRDYVQKAQTKEQADFAIEALAKATYERMFRWLVLRINKALDKTKRQGASFIGILDI 453
           + V  D V    +  ++ +A +AL KA Y RMF WLV RIN ++     Q    +G+LDI
Sbjct: 382 VAVKGDMVTTDLSVSESSYARDALCKALYSRMFSWLVHRINDSIKVRGAQRTKVMGVLDI 203

Query: 454 AGFEIFDLNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCID 513
            GFE+F+ NSFEQ  INY NEKLQQ+F       EQEEY +EGIEW  +++  +   C +
Sbjct: 202 YGFEVFENNSFEQFIINYCNEKLQQIFIELTLKEEQEEYIKEGIEWIHVEYFNNAVIC-E 26

Query: 514 LIEK 517
           LIEK
Sbjct: 25  LIEK 14
>01284
          Length = 1603

 Score = 92.0 bits (227), Expect = 2e-18,   Method: Compositional matrix adjust.
 Identities = 48/136 (35%), Positives = 75/136 (55%), Gaps = 5/136 (3%)
 Frame = +2

Query: 643 FRTVGQLYKEQLAKLMATLRNTNPNFVRCIIPNHEKKAGKLDPHL-----VLDQLRCNGV 697
           F +VG  +++QL  LM  L++T  NF+RCI PN      K+  HL     +L QL+C G+
Sbjct: 11  FISVGTKFRKQLLVLMDKLKSTGTNFIRCIKPN-----VKMVDHLFEGANILSQLQCAGM 175

Query: 698 LEGIRICRQGFPNRVVFQEFRQRYEILTPNSIPKGFMDGKQACVLMIKALELDSNLYRIG 757
           +  + + +QGFP+R  F E    Y+   P  + +  +D +  C  + KAL LD   ++ G
Sbjct: 176 VSVLELMQQGFPSRTPFSELYNMYKKYLPPELSR--LDPRLFCKSLFKALGLDDKDFKFG 349

Query: 758 QSKVFFRAGVLAHLEE 773
            +KVFFR G  A  ++
Sbjct: 350 LTKVFFRPGKFAEFDQ 397
>31878
          Length = 1178

 Score = 64.3 bits (155), Expect(2) = 2e-16,   Method: Compositional matrix adjust.
 Identities = 26/56 (46%), Positives = 40/56 (71%)
 Frame = -1

Query: 805  QLTAMKVLQRNCAAYLRLRNWQWWRLFTKVKPLLNSIRHEDELLAKEAELTKVREK 860
            Q  A++ +QRN   Y+++R W WW+L+TKVKP+LN  R E+ELL  +A+L  ++ K
Sbjct: 1064 QHLAVRCIQRNVQKYMKIREWSWWKLYTKVKPILNVHRTEEELLEAQADLEAMKTK 897

 Score = 41.2 bits (95), Expect(2) = 2e-16,   Method: Composition-based stats.
 Identities = 18/31 (58%), Positives = 22/31 (70%)
 Frame = -2

Query: 767  VLAHLEEERDLKITDVIIGFQACCRGYLARK 797
            VL+ LE  RD K+T ++  FQA CRGYL RK
Sbjct: 1177 VLSQLEAGRDEKLTGIVTQFQALCRGYLGRK 1085
>01074
          Length = 2584

 Score = 72.0 bits (175), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 52/150 (34%), Positives = 78/150 (52%)
 Frame = -2

Query: 1769 ERSHAQKNENARQQLERQNKELKAKLQEMESAVKSKYKASIAALEAKIAQLEEQLDNETK 1828
            ERS +QK EN R  LERQNKE++ KLQE+E   +++ KA+I     +  Q         +
Sbjct: 2583 ERSVSQKLENQRLALERQNKEMREKLQELEGQSRARTKATIGRTGGQDCQPGRTTGPGGQ 2404

Query: 1829 ERQAASKQVRRTEKKLKDVLLQVEDERRNAEQFKDQADKASTRXXXXXXXXXXXXXXXXX 1888
               +      +  +  + + +Q EDERR+A+Q+K+Q DK + R                 
Sbjct: 2403 GASSPGSHEPQDGQASQRLQIQAEDERRSADQYKEQLDKMNNRVKALKRQVDEAEEECAR 2224

Query: 1889 XNASRRKLQRELEDATETADAMNREVSSLK 1918
             NA +RK+QREL+D  E  D + RE  SL+
Sbjct: 2223 INAQKRKVQRELDDQMEQNDVLVRETQSLR 2134
>33963
          Length = 392

 Score = 47.8 bits (112), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 38/129 (29%), Positives = 55/129 (42%)
 Frame = +2

Query: 1411 LEKTKTRXXXXXXXXXXXXXXXXXSVSNLEKKQKKFDQLLAEEKTISXXXXXXXXXXXXX 1470
            LEK K R                 + +NLEKKQ+ FD+ +AE +                
Sbjct: 2    LEKAKARLQGELEDLMVDVERSNANANNLEKKQRAFDKTIAEWQAKVNDLQGELENAQKE 181

Query: 1471 XXXXXXXXLSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRAL 1530
                      +   LEEA++    L R NK    E+ DL     D G+SVHE EK+++ L
Sbjct: 182  ARGYSAELFRVKAQLEEAVDSTEALRRENKNLADEIHDLTDQLSDGGRSVHESEKARKRL 361

Query: 1531 EQQVEEMKT 1539
            E + EE++ 
Sbjct: 362  ELEKEELQA 388

 Score = 36.2 bits (82), Expect = 0.13,   Method: Compositional matrix adjust.
 Identities = 33/130 (25%), Positives = 67/130 (51%)
 Frame = +2

Query: 1495 LERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDA 1554
            LE+   + + E+EDLM   +    + + LEK +RA ++ + E + ++ +L+ EL+  +  
Sbjct: 2    LEKAKARLQGELEDLMVDVERSNANANNLEKKQRAFDKTIAEWQAKVNDLQGELENAQKE 181

Query: 1555 KLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAMAARKK 1614
                   L  +KAQ E  +   +    E  K L  ++ ++  +L D  +    +  ARK+
Sbjct: 182  ARGYSAELFRVKAQLEEAVDSTEALRRE-NKNLADEIHDLTDQLSDGGRSVHESEKARKR 358

Query: 1615 LEMDLKDLEA 1624
            LE++ ++L+A
Sbjct: 359  LELEKEELQA 388
>30605
          Length = 336

 Score = 35.0 bits (79), Expect = 0.26,   Method: Composition-based stats.
 Identities = 26/82 (31%), Positives = 43/82 (52%), Gaps = 6/82 (7%)
 Frame = -3

Query: 319 FQETMEAMRIMGIPEDEQMGLLRVISGVLQLGNIAFKKERNTDQA------SMPDNTAAQ 372
           F+   EAM  MG+ + ++M +  +++ VL LGNIAF+ + +  +          D+ A  
Sbjct: 316 FKVCDEAMTRMGVSDADKMAIFMLVAAVLHLGNIAFEDDHDDTKGGCKVLEEAEDSLATA 137

Query: 373 KVSHLLGINVTDFTRGILTPRI 394
            V  LLG++  +  R  LT RI
Sbjct: 136 AV--LLGVDKMEL-RDSLTSRI 80
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|21313012|ref|NP_083667.1| RAB4B, member RAS oncogene
family [Mus musculus]
         (213 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

08428                                                                 142   1e-34
33374                                                                 119   5e-31
34468                                                                 111   2e-25
01398                                                                 107   2e-24
14456                                                                 107   3e-24
17511                                                                 104   2e-23
26083                                                                 104   3e-23
07465                                                                 103   6e-23
05468                                                                 102   1e-22
33794                                                                  98   2e-21
33380                                                                  94   4e-20
13901                                                                  91   4e-19
32723                                                                  87   5e-18
01095                                                                  85   2e-17
01972                                                                  82   2e-16
07580                                                                  70   6e-16
30760                                                                  80   6e-16
27191                                                                  72   9e-16
13750                                                                  78   2e-15
11257                                                                  77   4e-15
26536                                                                  74   5e-14
13745                                                                  72   2e-13
29380                                                                  71   3e-13
35581                                                                  70   9e-13
19006                                                                  68   3e-12
34359                                                                  67   5e-12
12339                                                                  66   9e-12
09204                                                                  61   3e-10
11728                                                                  61   3e-10
25796                                                                  60   9e-10
00858                                                                  59   1e-09
14119                                                                  58   2e-09
00552                                                                  53   8e-08
34597                                                                  50   1e-07
19656                                                                  52   2e-07
14775                                                                  51   4e-07
08153                                                                  49   1e-06
10708                                                                  39   1e-06
31291                                                                  49   2e-06
19046                                                                  49   2e-06
24619                                                                  46   1e-05
09827                                                                  45   3e-05
33605                                                                  43   8e-05
10862                                                                  40   0.001
06994                                                                  30   1.00 
>08428
          Length = 1109

 Score =  142 bits (358), Expect = 1e-34,   Method: Compositional matrix adjust.
 Identities = 68/166 (40%), Positives = 103/166 (62%)
 Frame = -3

Query: 10   KFLVIGSAGTGKSCLLHQFIENKFKQDSNHTIGVEFGSRVVNVGGKTVKLQIWDTAGQER 69
            K  ++G +G GKS ++ +F+   ++     TIG  F S+ + V G   + QIWDTAGQE+
Sbjct: 1065 KVCLLGDSGVGKSSIVLRFVTGSYRPSQESTIGASFMSKSLVVDGAGYRFQIWDTAGQEK 886

Query: 70   FRSVTRSYYRGAAGALLVYDITSRETYNSLAAWLTDARTLASPNIVVILCGNKKDLDPER 129
            FR++   YYRGAA A++VYD+T   T+ S+ +W+ + R+   PNIV+ + GNK DL+  R
Sbjct: 885  FRALAPMYYRGAAAAVIVYDVTRPRTFKSVKSWIQELRSFGPPNIVLAIAGNKCDLEELR 706

Query: 130  EVTFLEASRFAQENELMFLETSALTGENVEEAFLKCARTILNKIDS 175
            EV   +A  +A     +F ETSA+T  NVEE F + AR +  + D+
Sbjct: 705  EVVEKDAQEYASSISAIFGETSAMTAVNVEEMFTELARQLPPEEDN 568
>33374
          Length = 489

 Score =  119 bits (299), Expect(2) = 5e-31,   Method: Compositional matrix adjust.
 Identities = 57/116 (49%), Positives = 79/116 (68%)
 Frame = +1

Query: 45  FGSRVVNVGGKTVKLQIWDTAGQERFRSVTRSYYRGAAGALLVYDITSRETYNSLAAWLT 104
           F ++ V +   TVK +IWDTAGQER+ S+   YYRGA  A++VYDIT+++T+     W+ 
Sbjct: 139 FLTQTVCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNQDTFGRAKTWVK 318

Query: 105 DARTLASPNIVVILCGNKKDLDPEREVTFLEASRFAQENELMFLETSALTGENVEE 160
           + +  ASPNIV+ L GNK DL  +R V F EA  +A+EN L+F+ETSA T  NV +
Sbjct: 319 ELQRQASPNIVIALAGNKADLANKRMVEFEEAQAYAEENSLLFMETSAKTAMNVND 486

 Score = 31.2 bits (69), Expect(2) = 5e-31,   Method: Compositional matrix adjust.
 Identities = 13/37 (35%), Positives = 23/37 (62%)
 Frame = +2

Query: 9  FKFLVIGSAGTGKSCLLHQFIENKFKQDSNHTIGVEF 45
          FK +++G +  GKS L+ +F++ +F +    TIG  F
Sbjct: 32 FKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAF 142
>34468
          Length = 1502

 Score =  111 bits (278), Expect = 2e-25,   Method: Compositional matrix adjust.
 Identities = 71/203 (34%), Positives = 107/203 (52%), Gaps = 9/203 (4%)
 Frame = +1

Query: 8   LFKFLVIGSAGTGKSCLLHQFIENKFKQDSNHTIGVEFGSRVVNVGGKTVKLQIWDTAGQ 67
           +FK +VIG +  GK+CL ++F   KF   +  TIGV+F  + + V  + +KLQ+WDTAGQ
Sbjct: 493 IFKIIVIGDSNVGKTCLTYRFCLGKFPDKTEATIGVDFREKSIQVDSEHLKLQLWDTAGQ 672

Query: 68  ERFR-SVTRSYYRGAAGALLVYDITSRETYNSLAAWLTDA-RTLASPNIVVILCGNKKDL 125
           ERFR S+ + YYR     + VYD+T   ++ ++ AW+ +  R   +  I  IL GNK D+
Sbjct: 673 ERFRKSMVQHYYRNVHAVVFVYDMTKMSSFENMPAWIEECDRHNLTKYIPRILVGNKCDV 852

Query: 126 DPEREVTFLEASRFAQENELMFLETSALTGE---NVEEAFLKCARTILNKIDSGELDPER 182
                V    A +FA  + +   ETSA   E   +V+  F+  A  +     S  + P  
Sbjct: 853 VERIAVNTNLAQKFADAHNMPLFETSAKDDEKANHVDAIFMTVAHKLKX---SKPMMPAH 1023

Query: 183 MGSGIQYGDIS---LRQLR-QPR 201
           +   +  GD+S   L  LR  PR
Sbjct: 1024LSEMVP-GDVSHGDLVHLRGSPR 1089
>01398
          Length = 1421

 Score =  107 bits (268), Expect = 2e-24,   Method: Compositional matrix adjust.
 Identities = 56/150 (37%), Positives = 82/150 (54%), Gaps = 3/150 (2%)
 Frame = -2

Query: 67   QERFRSVTRSYYRGAAGALLVYDITSRETYNSLAAWLTDARTLASPNIVVILC-GNKKDL 125
            QERFRS+TRSYYR + G ++VYDIT R T+ +L  W  +AR    P+  + L  G+K D 
Sbjct: 1420 QERFRSITRSYYRNSVGVIIVYDITKRSTFENLKQWYEEARNHIEPHKAIFLVLGHKSDR 1241

Query: 126  DPEREVTFLEASRFAQENELMFLETSALTGENVEEAFLKCARTILNKIDSGELDPERMGS 185
            +  R+VT  E  RFA+ + L F ETSA +G N+E+ F + A+     +  G +  E    
Sbjct: 1240 EDARQVTAREGRRFAEMHGLKFFETSAKSGHNIEDVFAQIAKDTYQHLQDGHIRLEEGWD 1061

Query: 186  GIQYGDISLRQLRQPRSAQAVA--PQPCGC 213
            G++ G        +PR    +A   +  GC
Sbjct: 1060 GVKQG------FARPRETVHLAEGEESGGC 989
>14456
          Length = 1867

 Score =  107 bits (267), Expect = 3e-24,   Method: Compositional matrix adjust.
 Identities = 65/170 (38%), Positives = 95/170 (55%), Gaps = 5/170 (2%)
 Frame = -1

Query: 14   IGSAGTGKSCLLHQFIENKFKQDSNHTIGVEFGSRVVNVGGKTVKLQIWDTAGQERFRSV 73
            +   G GKS L+++F+ NKF   S HTIGVEF ++ V V  +T  +QIWDTAGQERF+S+
Sbjct: 1123 LKQGGVGKSSLMNRFVSNKFDAQSFHTIGVEFLNKDVVVDDETYTMQIWDTAGQERFKSL 944

Query: 74   TRSYYRGAAGALLVYDITSRETYNSLAAW----LTDARTLASPNIVVILCGNKKDLDPER 129
               +YRGA   LL + + S +++ +L+ W    L  A          ++ GNK D++  R
Sbjct: 943  RTPFYRGADCCLLTFSVDSMQSFRNLSMWRKEFLYYADIQDGVTFPFVVLGNKIDVEG-R 767

Query: 130  EVTFLEASRFAQEN-ELMFLETSALTGENVEEAFLKCARTILNKIDSGEL 178
            +VT  EA  +   N    + ETSA    NVE+AFL   + +    D  E+
Sbjct: 766  QVTNEEARSWCTANSNAPYFETSAKDATNVEKAFLAAVQRLREVEDQQEV 617
>17511
          Length = 483

 Score =  104 bits (260), Expect = 2e-23,   Method: Compositional matrix adjust.
 Identities = 52/129 (40%), Positives = 78/129 (60%), Gaps = 4/129 (3%)
 Frame = -3

Query: 1   MAETYDFLFKFLVIGSAGTGKSCLLHQFIENKFKQDSNHTIGVEFGSRVVNVGGKTVKLQ 60
           MA     L K +++G +G GK+ L++Q++  KF      TIG +F ++ V V  + V +Q
Sbjct: 388 MASRKKVLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQ 209

Query: 61  IWDTAGQERFRSVTRSYYRGAAGALLVYDITSRETYNSLAAWLTDARTLASP----NIVV 116
           IWDTAGQERF+S+  ++YRGA   +LV+D+T   T+ SL +W  +    ASP    N   
Sbjct: 208 IWDTAGQERFQSLGVAFYRGADCCVLVFDVTMPNTFRSLDSWRDEFLIQASPRDPENFPF 29

Query: 117 ILCGNKKDL 125
           ++ GNK DL
Sbjct: 28  VVIGNKIDL 2
>26083
          Length = 432

 Score =  104 bits (259), Expect = 3e-23,   Method: Compositional matrix adjust.
 Identities = 44/114 (38%), Positives = 76/114 (66%)
 Frame = +1

Query: 9   FKFLVIGSAGTGKSCLLHQFIENKFKQDSNHTIGVEFGSRVVNVGGKTVKLQIWDTAGQE 68
           FK + +G    GK+ L+ +F+ + F      TIG++F S+ + +  +T++LQ+WDTAGQE
Sbjct: 79  FKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTIRLQLWDTAGQE 258

Query: 69  RFRSVTRSYYRGAAGALLVYDITSRETYNSLAAWLTDARTLASPNIVVILCGNK 122
           RFRS+  SY R ++ A++VYDIT+  +++  + W+ D RT    +++++L GNK
Sbjct: 259 RFRSLIPSYIRDSSVAVVVYDITNANSFHQTSKWIDDVRTERGSDVIIMLVGNK 420
>07465
          Length = 1103

 Score =  103 bits (257), Expect = 6e-23,   Method: Compositional matrix adjust.
 Identities = 56/170 (32%), Positives = 93/170 (54%), Gaps = 4/170 (2%)
 Frame = +3

Query: 22  SCLLHQFIENKFKQDSNHTIGVEFGSRVVNVGGKTVKLQIWDTAGQERFRSVTRSYYRGA 81
           S ++ ++ +  F +D   TIGV+F  R + VGG+ V+L +WDTAGQE F ++T++YYRGA
Sbjct: 240 SSMIQRYCKGIFTKDYKKTIGVDFLERQIEVGGEDVRLMLWDTAGQEEFDAITKAYYRGA 419

Query: 82  AGALLVYDITSRETYNSLAAWLTDARTLASPNIVVILCGNKKDLDPEREVTFLEASRFAQ 141
              +L +    R+++ +L  W           I +++  NK DL  +  V   EA   A+
Sbjct: 420 QACVLAFSTVDRDSFEALETWKRKVEDEVGE-IGMVIVQNKIDLIDDAVVRPEEAENLAK 596

Query: 142 ENELMFLETSALTGENVEEAFLKCARTILNKIDSG----ELDPERMGSGI 187
           +  L F  TS     NV+E F   A   L+++++G     L P+++G G+
Sbjct: 597 KLRLRFYRTSVKENMNVDEVFRYLADKYLHQLNTGMDEVNLTPQKIGQGL 746
>05468
          Length = 1558

 Score =  102 bits (253), Expect = 1e-22,   Method: Compositional matrix adjust.
 Identities = 64/179 (35%), Positives = 99/179 (55%), Gaps = 8/179 (4%)
 Frame = -3

Query: 3    ETYDFLFKFLVIGSAGTGKSCLLHQFIENKFKQDSNHTIGVEFGSRVVNVGGKT-VKLQI 61
            E  + L+K LVIG  GTGK+ ++ +++   F Q    TIGV+F  +V+N    T ++LQ+
Sbjct: 1556 EKKEHLYKILVIGELGTGKTSIIKRYVHQFFSQHYRATIGVDFALKVLNWDADTLIRLQL 1377

Query: 62   WDTAGQERFRSVTRSYYRGAAGALLVYDITSRETYNSLAAWLTDARTLA-----SPNIVV 116
            WD AGQERF ++TR YY+ A GA +V+D+T   T++++  W  D  +       SP +  
Sbjct: 1376 WDIAGQERFGNMTRVYYKEAVGAFVVFDVTRASTFDAVTKWKNDLDSKVQLADGSP-VPC 1200

Query: 117  ILCGNKKDLDPEREVTFL-EASRFAQENELM-FLETSALTGENVEEAFLKCARTILNKI 173
            +L  NK D   E  V    +   F  E   + + ETSA    N++EA    AR ++ +I
Sbjct: 1199 VLLANKCDQAKEGLVNNTSQMDEFCSEKGFIGWYETSAKENINIDEA----ARFLVTRI 1035
>33794
          Length = 779

 Score = 98.2 bits (243), Expect = 2e-21,   Method: Compositional matrix adjust.
 Identities = 51/130 (39%), Positives = 78/130 (60%)
 Frame = -1

Query: 43  VEFGSRVVNVGGKTVKLQIWDTAGQERFRSVTRSYYRGAAGALLVYDITSRETYNSLAAW 102
           V + +  + + GK VKLQIWDT+GQ RF ++ RSY RGA G +LVYDIT++ +++ +  W
Sbjct: 692 VAYKTTTILLEGKRVKLQIWDTSGQGRFCTIIRSYSRGAQGIILVYDITNKWSFDGIDRW 513

Query: 103 LTDARTLASPNIVVILCGNKKDLDPEREVTFLEASRFAQENELMFLETSALTGENVEEAF 162
           L +    A P I  +L GN+  L  +R+V   +A  +A  N +   E S L   N+ E+F
Sbjct: 512 LKEVEEHA-PGIPKVLVGNRLHLAYKRQVAAKQAETYASRNNMSCFEISPLCDFNIRESF 336

Query: 163 LKCARTILNK 172
            + AR  L++
Sbjct: 335 CELARMALHR 306
>33380
          Length = 282

 Score = 94.0 bits (232), Expect = 4e-20,   Method: Compositional matrix adjust.
 Identities = 41/75 (54%), Positives = 57/75 (76%)
 Frame = +3

Query: 55  KTVKLQIWDTAGQERFRSVTRSYYRGAAGALLVYDITSRETYNSLAAWLTDARTLASPNI 114
           K VKLQIWDTAGQER+R++T +YYRGA G +L+YD+T+ E++N++  W T  +T +  N 
Sbjct: 54  KRVKLQIWDTAGQERYRTITTAYYRGAMGFILMYDVTNEESFNAVQDWCTQIKTYSWDNA 233

Query: 115 VVILCGNKKDLDPER 129
            V+L GNK DL+ ER
Sbjct: 234 QVVLVGNKCDLEDER 278
>13901
          Length = 962

 Score = 90.9 bits (224), Expect = 4e-19,   Method: Compositional matrix adjust.
 Identities = 38/96 (39%), Positives = 62/96 (64%), Gaps = 1/96 (1%)
 Frame = -3

Query: 8   LFKFLVIGSAGTGKSCLLHQFIENKFKQDSNHTIGVEFGSRVVNVGGK-TVKLQIWDTAG 66
           LFK ++IG    GK+  + +++ + F++D   TIGV+F  +V+    K  +KLQ+WD AG
Sbjct: 288 LFKVIIIGDPTVGKTSFVQRYVNDSFRRDYKMTIGVDFALKVIRWSDKCNIKLQLWDIAG 109

Query: 67  QERFRSVTRSYYRGAAGALLVYDITSRETYNSLAAW 102
           QERF S+TR YY+ A   ++++D+T + TY +   W
Sbjct: 108 QERFTSMTRVYYKDAHACIVMFDLTQKNTYQNAIRW 1
>32723
          Length = 384

 Score = 87.0 bits (214), Expect = 5e-18,   Method: Compositional matrix adjust.
 Identities = 42/96 (43%), Positives = 59/96 (61%)
 Frame = +2

Query: 67  QERFRSVTRSYYRGAAGALLVYDITSRETYNSLAAWLTDARTLASPNIVVILCGNKKDLD 126
           QERFRS+T+SYYR A   +LVYD+ S+++Y SL  W+ +    A   ++  L GNK D  
Sbjct: 2   QERFRSITQSYYRSANALILVYDVCSQQSYESLPQWIHEIELYAGTKVLAFLVGNKIDQT 181

Query: 127 PEREVTFLEASRFAQENELMFLETSALTGENVEEAF 162
            +RE+       FA+  E+ FLETSA   +NVE+ F
Sbjct: 182 DKREIPTHIGKEFAERYEMRFLETSAKEADNVEKLF 289
>01095
          Length = 1745

 Score = 85.1 bits (209), Expect = 2e-17,   Method: Compositional matrix adjust.
 Identities = 42/99 (42%), Positives = 60/99 (60%)
 Frame = -1

Query: 86   LVYDITSRETYNSLAAWLTDARTLASPNIVVILCGNKKDLDPEREVTFLEASRFAQENEL 145
            +VYDIT+++T+     W+ + +  ASPNIV+ L GNK DL  +R V F EA  +A+EN L
Sbjct: 1745 VVYDITNQDTFGRAKTWVKELQRQASPNIVIALAGNKADLANKRMVEFEEAQAYAEENSL 1566

Query: 146  MFLETSALTGENVEEAFLKCARTILNKIDSGELDPERMG 184
            +F+ETSA T  NV + FL  A+ +      G   P + G
Sbjct: 1565 LFMETSAKTAMNVNDIFLAIAKKLPKNEGGGGSQPRQQG 1449
>01972
          Length = 2359

 Score = 82.0 bits (201), Expect = 2e-16,   Method: Compositional matrix adjust.
 Identities = 45/131 (34%), Positives = 74/131 (56%)
 Frame = +3

Query: 40  TIGVEFGSRVVNVGGKTVKLQIWDTAGQERFRSVTRSYYRGAAGALLVYDITSRETYNSL 99
           T+GVE    + +     +K  +WDTAGQE+F  +   YY     A++++D+TSR TY ++
Sbjct: 396 TLGVEVHPLLFHTSRGKLKFNVWDTAGQEKFGGLRDGYYIQGQCAVIMFDVTSRVTYKNV 575

Query: 100 AAWLTDARTLASPNIVVILCGNKKDLDPEREVTFLEASRFAQENELMFLETSALTGENVE 159
             W  D   +   NI ++LCGNK D+  +R+V   +A  F ++  L + + SA +  N E
Sbjct: 576 PNWHRDLVRVCE-NIPIVLCGNKVDIK-DRKVK-AKAIVFHRKKNLQYYDISAKSNYNFE 746

Query: 160 EAFLKCARTIL 170
           + FL  AR ++
Sbjct: 747 KPFLWLARKLV 779
>07580
          Length = 921

 Score = 70.1 bits (170), Expect(2) = 6e-16,   Method: Compositional matrix adjust.
 Identities = 48/136 (35%), Positives = 67/136 (49%), Gaps = 1/136 (0%)
 Frame = +3

Query: 50  VNVGGKTVKLQIWDTAGQERFRSVTRSYYRGAAGALLVYDITSRETYNSLAAWLTDA-RT 108
           V V G+   L+I DTAG E+F ++   Y +   G LL Y IT++ T+N L        R 
Sbjct: 183 VEVDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFLLAYSITAQSTFNDLQELREQILRV 362

Query: 109 LASPNIVVILCGNKKDLDPEREVTFLEASRFAQENELMFLETSALTGENVEEAFLKCART 168
             + ++ ++L GNK DL+ ER V   +    A+     FLETSA    NV E F+   R 
Sbjct: 363 KDTDDVPMLLVGNKCDLEDERVVGKDQGQGLARSFSCAFLETSAKARINVNEIFMDLVRQ 542

Query: 169 ILNKIDSGELDPERMG 184
           I  K       PE+ G
Sbjct: 543 INKK------SPEQSG 572

 Score = 30.4 bits (67), Expect(2) = 6e-16,   Method: Compositional matrix adjust.
 Identities = 12/25 (48%), Positives = 17/25 (68%)
 Frame = +2

Query: 9  FKFLVIGSAGTGKSCLLHQFIENKF 33
          +K +V+GS G GKS L  QF++  F
Sbjct: 62 YKLVVLGSGGVGKSALTVQFVQGDF 136
>30760
          Length = 596

 Score = 80.1 bits (196), Expect = 6e-16,   Method: Compositional matrix adjust.
 Identities = 53/175 (30%), Positives = 87/175 (49%), Gaps = 6/175 (3%)
 Frame = -1

Query: 10  KFLVIGSAGTGKSCLLHQFIEN--KFKQDSNHTIGVEFGSRVVNVGGK--TVKLQIWDTA 65
           K +V G +G GKS +   F  +   F ++ + T GVE   ++VN+      V+L ++D+A
Sbjct: 524 KCIVTGDSGVGKSSICQVFHSDSAHFPKNYSMTTGVEVLVKLVNIPDSRDQVELYLFDSA 345

Query: 66  GQERFRSVTRSYYRGAAGALLVYDITSRETYNSLAAWLTDARTLASPNIVV--ILCGNKK 123
           G+E F      ++   +  ++VYD+T   +++    WL   R  A PN V+  +L  NK 
Sbjct: 344 GKEIFSENVTKFWDQPSVVMVVYDVTDETSFSGCVRWLERVRA-AKPNTVIPGVLVANKT 168

Query: 124 DLDPEREVTFLEASRFAQENELMFLETSALTGENVEEAFLKCARTILNKIDSGEL 178
           DLD  R V+  E    AQ + L + E SA   +N +  F  C     +K+   +L
Sbjct: 167 DLDERRRVSRKEGKDLAQSHGLEYFECSAKEMQNTDTPFF-CLAHAFHKLYQEQL 6
>27191
          Length = 443

 Score = 72.0 bits (175), Expect(2) = 9e-16,   Method: Compositional matrix adjust.
 Identities = 28/102 (27%), Positives = 59/102 (57%)
 Frame = +1

Query: 21  KSCLLHQFIENKFKQDSNHTIGVEFGSRVVNVGGKTVKLQIWDTAGQERFRSVTRSYYRG 80
           K+CL+  F E+KF Q    T+GV++G ++  V G  +++ +WD +G   +  V    Y G
Sbjct: 1   KTCLIKHFCESKFNQGYQPTVGVDYGFKIQTVNGVDMRVHMWDLSGSNEYLDVRNELYTG 180

Query: 81  AAGALLVYDITSRETYNSLAAWLTDARTLASPNIVVILCGNK 122
           +    +V+D+++  ++ +L +WL +    A+ + + ++ GN+
Sbjct: 181 SDAIFIVFDVSNTPSFEALDSWLREINRFATGSPLNVIVGNR 306

 Score = 27.7 bits (60), Expect(2) = 9e-16,   Method: Compositional matrix adjust.
 Identities = 11/27 (40%), Positives = 18/27 (66%)
 Frame = +2

Query: 136 ASRFAQENELMFLETSALTGENVEEAF 162
           + + A  N+ ++ ETSA TGE V++ F
Sbjct: 344 SKKVALHNKCLYYETSAATGEGVDDMF 424
>13750
          Length = 503

 Score = 78.2 bits (191), Expect = 2e-15,   Method: Compositional matrix adjust.
 Identities = 50/149 (33%), Positives = 75/149 (50%), Gaps = 3/149 (2%)
 Frame = -2

Query: 21  KSCLLHQFIENKFKQDSNHTIGV---EFGSRVVNVGGKTVKLQIWDTAGQERFRSVTRSY 77
           K+CLL ++ +  F   +  TI V   EF           V+  +WDT G E +RS+  S+
Sbjct: 502 KTCLLRRYQKGFFMDRTMPTIAVLCSEFNES--RTDPLNVRYTLWDTGGAETYRSLWVSH 329

Query: 78  YRGAAGALLVYDITSRETYNSLAAWLTDARTLASPNIVVILCGNKKDLDPEREVTFLEAS 137
           +RGA  ALLVYD+T   ++ +       A     P   VI  G+K DL+  R ++     
Sbjct: 328 FRGAQVALLVYDVTCEWSFLTATTVWRKALMKNIPEAQVIFVGSKTDLEENRVISTERGQ 149

Query: 138 RFAQENELMFLETSALTGENVEEAFLKCA 166
            FA +    F ETS++TG+NV+  F + A
Sbjct: 148 AFATQCGYTFFETSSVTGKNVDAVFWEIA 62
>11257
          Length = 1102

 Score = 77.4 bits (189), Expect = 4e-15,   Method: Compositional matrix adjust.
 Identities = 45/125 (36%), Positives = 72/125 (57%), Gaps = 5/125 (4%)
 Frame = -2

Query: 50   VNVGGKTVKLQIWDTAGQERFRSVTRSYYRGAAGALLVYDITSRETYNSLAAWLTDARTL 109
            V V G+T  +QIWDTAGQER++S+   +YRG    LL + + + ++  SL+ W  +    
Sbjct: 1047 VVVDGETFTMQIWDTAGQERYKSLRTPFYRGTDCCLLTFSVDNLKSLQSLSDWYDEFVNY 868

Query: 110  A----SPNIVVILCGNKKDLDPEREVTFLEASRFAQEN-ELMFLETSALTGENVEEAFLK 164
            A    S +   ++ GNK D++ EREV+  +A  + + +  L + ETSA    NV++AFL 
Sbjct: 867  ADIQDSASFPFVIIGNKADIE-EREVSSEDAYNWCRTHGNLPYFETSAKDSLNVQQAFLA 691

Query: 165  CARTI 169
              R +
Sbjct: 690  VVRRL 676
>26536
          Length = 829

 Score = 73.6 bits (179), Expect = 5e-14,   Method: Compositional matrix adjust.
 Identities = 43/118 (36%), Positives = 64/118 (54%), Gaps = 3/118 (2%)
 Frame = +2

Query: 55  KTVKLQIWDTAGQERFRSVTRSYYRGAAGALLVY---DITSRETYNSLAAWLTDARTLAS 111
           + V     DTAGQE + S+   Y R   G ++VY   D+TS +   ++  WLT  R    
Sbjct: 122 RRVSWTFLDTAGQEEYSSMREHYTRSGDGFIVVYSVTDVTSFQEAEAVFRWLT--RFQDE 295

Query: 112 PNIVVILCGNKKDLDPEREVTFLEASRFAQENELMFLETSALTGENVEEAFLKCARTI 169
            +I  +LCGNK DL  +R+VT  E  + A    +++ ETSA TG+NV + +    R+I
Sbjct: 296 TSIHAVLCGNKTDLTSDRKVTPEEGRKMADRLGMLYFETSAKTGDNVSQVYHGLLRSI 469
>13745
          Length = 1045

 Score = 72.0 bits (175), Expect = 2e-13,   Method: Compositional matrix adjust.
 Identities = 44/117 (37%), Positives = 69/117 (58%), Gaps = 5/117 (4%)
 Frame = +2

Query: 67  QERFRSVTRSYYRGAAGALLVYDITSRETYNSLAAWLTDARTLASP----NIVVILCGNK 122
           QERF+S+  ++YRGA   +LVYD+T+  ++ +L +W  +    ASP    +   ++ GNK
Sbjct: 2   QERFQSLGVAFYRGADCCVLVYDVTAPNSFKNLDSWRDEFLIQASPRDPEHFPFVVLGNK 181

Query: 123 KDLDPEREVTFLEASRFAQ-ENELMFLETSALTGENVEEAFLKCARTILNKIDSGEL 178
            DLD  R+V+   A ++ Q +N++ + ETSA  G NVE AF   A+  L +    EL
Sbjct: 182 VDLD-NRQVSTRRAQQWCQSKNDIPYYETSAKEGINVEMAFQTIAKNALEQETEAEL 349
>29380
          Length = 853

 Score = 71.2 bits (173), Expect = 3e-13,   Method: Compositional matrix adjust.
 Identities = 39/103 (37%), Positives = 63/103 (61%), Gaps = 1/103 (0%)
 Frame = -2

Query: 81  AAGALLVYDITSRETYNSLAAWLTDARTLASPNIVVILCGNKKDLDPE-REVTFLEASRF 139
           A+ A++VYD+   +T++   AW+ + R   + ++++IL GNK DL  + R V+F +A  F
Sbjct: 852 ASAAIIVYDVNIADTFSRALAWVKELRQQNTESVLIILAGNKVDLATQHRAVSFEDAQSF 673

Query: 140 AQENELMFLETSALTGENVEEAFLKCARTILNKIDSGELDPER 182
           A+EN L+F E SA TG  V E F+    T+ N++   E+D  R
Sbjct: 672 ARENGLLFAEVSAKTGMAVNEIFM----TLANQLIQQEIDGSR 556
>35581
          Length = 364

 Score = 69.7 bits (169), Expect = 9e-13,   Method: Compositional matrix adjust.
 Identities = 36/83 (43%), Positives = 49/83 (59%), Gaps = 2/83 (2%)
 Frame = +2

Query: 9   FKFLVIGSAGTGKSCLLHQFIENKFKQDSNHT--IGVEFGSRVVNVGGKTVKLQIWDTAG 66
           FK +++G AG GK+CLL++   +KF  DS  T        + V    G    + +WDTAG
Sbjct: 47  FKCVLLGDAGVGKTCLLNRLATDKF-LDSPLTSLTTASLLTTVTLTSGVMASVDLWDTAG 223

Query: 67  QERFRSVTRSYYRGAAGALLVYD 89
           QER+RS+T SYYR     L+VYD
Sbjct: 224 QERYRSLTSSYYRDTKAVLIVYD 292
>19006
          Length = 568

 Score = 67.8 bits (164), Expect = 3e-12,   Method: Compositional matrix adjust.
 Identities = 37/117 (31%), Positives = 62/117 (52%), Gaps = 1/117 (0%)
 Frame = -2

Query: 10  KFLVIGSAGTGKSCLLHQFIENKFKQDSNHTIGVEFGSRVVNVGGKTVKLQIWDTAGQER 69
           K +++G    GK+CLL  F +++F +    T+   + + +  V  K V+L +WDTAGQE 
Sbjct: 432 KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADI-EVDSKQVELALWDTAGQED 256

Query: 70  FRSVTRSYYRGAAGALLVYDITSRETYNSLA-AWLTDARTLASPNIVVILCGNKKDL 125
           +  +    Y      L+ + I S ++  ++   W  + R    PN+ +IL GNKKDL
Sbjct: 255 YDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVRHFC-PNVPIILVGNKKDL 88
>34359
          Length = 1042

 Score = 67.0 bits (162), Expect = 5e-12,   Method: Compositional matrix adjust.
 Identities = 41/131 (31%), Positives = 70/131 (53%)
 Frame = +3

Query: 1   MAETYDFLFKFLVIGSAGTGKSCLLHQFIENKFKQDSNHTIGVEFGSRVVNVGGKTVKLQ 60
           MAE  +F  K +++G      + ++ + +    K+    T+GVE      N     ++  
Sbjct: 36  MAEVPNF--KLVLVGGRWEWANNIVKRHVTGS*KKYV-ATLGVEVHPLQFNTSRGLLRFN 206

Query: 61  IWDTAGQERFRSVTRSYYRGAAGALLVYDITSRETYNSLAAWLTDARTLASPNIVVILCG 120
           +WDTAGQE+F  +   YY     A++++D+TSR TY ++  W  D   +   NI ++LCG
Sbjct: 207 VWDTAGQEKFGGLRDGYYIQGTCAIIMFDVTSRVTYKNVPNWHRDLVRVCE-NIPIVLCG 383

Query: 121 NKKDLDPEREV 131
           NK D+  +R+V
Sbjct: 384 NKVDIK-DRKV 413
>12339
          Length = 578

 Score = 66.2 bits (160), Expect = 9e-12,   Method: Compositional matrix adjust.
 Identities = 43/118 (36%), Positives = 66/118 (55%), Gaps = 5/118 (4%)
 Frame = -2

Query: 67  QERFRSVTRSYYRGAAGALLVYDITSRETYNSLAAWLTDARTLASP----NIVVILCGNK 122
           QERF+S+  ++YRGA   +LVYD+T  +T++SL +W  +    ASP    +   ++ GNK
Sbjct: 577 QERFQSLGVAFYRGADCCILVYDVTEXKTFDSLDSWQREFLNQASPRDPEHFPFVVIGNK 398

Query: 123 KDLDPEREVTFLEASRF-AQENELMFLETSALTGENVEEAFLKCARTILNKIDSGELD 179
            DLD  R VT      + + +  + + ETSA    NVE+AF   A+  L +    E+D
Sbjct: 397 IDLD-NRVVTAKRGQGWCSTKGGIPYFETSAKEAINVEQAFQTVAKNALAQESEVEID 227
>09204
          Length = 1051

 Score = 61.2 bits (147), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 35/108 (32%), Positives = 59/108 (54%), Gaps = 4/108 (3%)
 Frame = -3

Query: 69   RFRSVTRSYYRGAAGALLVYDITSRETYNSLAAWLTDARTLASPNIVVILCGNKKDL--- 125
            R+ +++R YYRGA  A+L +D+T + +++ +  W+ + R        + +CG K DL   
Sbjct: 1049 RYEAMSRIYYRGAKAAILCFDLTDKSSFDRIRFWIGELRQ-HEEECKLYICGTKFDLVHD 873

Query: 126  DPERE-VTFLEASRFAQENELMFLETSALTGENVEEAFLKCARTILNK 172
            DPER  V    A   A +      ETS++TG+N+E+ F K A   + +
Sbjct: 872  DPERRAVPRSVAKALADDCMAEIYETSSMTGDNIEKLFTKIAEDYMKE 729
>11728
          Length = 635

 Score = 61.2 bits (147), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 43/159 (27%), Positives = 73/159 (45%), Gaps = 13/159 (8%)
 Frame = -1

Query: 9   FKFLVIGSAGTGKSCLLHQFIENKFKQDSNHTIGVEFGSRVVNVGGKTVKLQIWDTAGQE 68
            K +V+G    GK+CLL  +  N F  +   T+   + + V+ V  K + L +WDTAGQE
Sbjct: 488 IKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVM-VDSKPINLGLWDTAGQE 312

Query: 69  RFRSVTRSYYRGAAGALLVYDITSRETYNSLAAWLTDARTLASPNIVVILCGNKKDLDPE 128
            +  +    Y      L+ + + S  ++ ++ A      +   PN  +IL G K DL  +
Sbjct: 311 DYDRLRPLSYPQTDVFLICFSLISPASFENVKAKWYPEVSHHCPNTPIILVGTKLDLRED 132

Query: 129 RE------------VTFLEASRFAQE-NELMFLETSALT 154
           +E            +T+ +    A++     +LE SALT
Sbjct: 131 KETIEKLKEKKLAPITYPQGLAMAKDIGAGKYLECSALT 15
>25796
          Length = 422

 Score = 59.7 bits (143), Expect = 9e-10,   Method: Compositional matrix adjust.
 Identities = 24/29 (82%), Positives = 28/29 (96%)
 Frame = -1

Query: 1  MAETYDFLFKFLVIGSAGTGKSCLLHQFI 29
          M+ETYD+LFKFL+IGSAG+GKSCLLH FI
Sbjct: 89 MSETYDYLFKFLIIGSAGSGKSCLLHHFI 3
>00858
          Length = 1658

 Score = 59.3 bits (142), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 49/162 (30%), Positives = 83/162 (51%), Gaps = 1/162 (0%)
 Frame = -2

Query: 9    FKFLVIGSAGTGKSCLLHQFIENKFKQDSNHTIGVEFGSRVVNVGGKTVKLQIWDTAGQE 68
            +K +V+G+ G GKS L  Q  +N F ++ + T       +VV + G+T  L I DTAGQE
Sbjct: 1588 YKLVVVGAGGVGKSALTIQLXQNHFVEEYDPTXEDSXRKQVV-IDGETCLLDILDTAGQE 1412

Query: 69   RFRSVTRSYYRGAAGALLVYDITSRETYNSLAAWLTDARTLASPNIV-VILCGNKKDLDP 127
               ++     R   G L V+ + + +++  +  +    + +   + V ++L GNK DL P
Sbjct: 1411 EXSAMRDQCMRTGEGFLCVFAVXNLKSFEDINQYREQIKRVKDADEVPMVLVGNKVDL-P 1235

Query: 128  EREVTFLEASRFAQENELMFLETSALTGENVEEAFLKCARTI 169
             R V   +    A+   + ++ETSA T + V++AF    R I
Sbjct: 1234 IRNVEQRQGKHMAELYHIPYVETSAKTRQGVDDAFYTLVREI 1109
>14119
          Length = 602

 Score = 58.2 bits (139), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 30/83 (36%), Positives = 49/83 (59%), Gaps = 1/83 (1%)
 Frame = +1

Query: 95  TYNSLAAWLTDARTLASPNIVVILCGNKKDLDPE-REVTFLEASRFAQENELMFLETSAL 153
           T+N   AW+ + R   + +++++L GNK DL  E R V+  +A  FA++N L+F E SA 
Sbjct: 1   TFNRALAWVKELRQQNAGSVLIVLAGNKADLASEHRAVSADDARTFAEDNGLIFAEVSAK 180

Query: 154 TGENVEEAFLKCARTILNKIDSG 176
           TG  V E F+  A  ++ + + G
Sbjct: 181 TGMAVSEVFMTIAHKLVRRAEEG 249
>00552
          Length = 455

 Score = 53.1 bits (126), Expect = 8e-08,   Method: Compositional matrix adjust.
 Identities = 25/53 (47%), Positives = 36/53 (67%)
 Frame = -1

Query: 8   LFKFLVIGSAGTGKSCLLHQFIENKFKQDSNHTIGVEFGSRVVNVGGKTVKLQ 60
           L K +++G  G GKS L+++F+ NKF   S HTIGVEF ++ V V G+T  +Q
Sbjct: 446 LLKVVLLGDGGVGKSSLMNRFVSNKFDAQSFHTIGVEFLTKDVVVDGETFTMQ 288

 Score = 44.3 bits (103), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 18/42 (42%), Positives = 28/42 (66%)
 Frame = -3

Query: 61  IWDTAGQERFRSVTRSYYRGAAGALLVYDITSRETYNSLAAW 102
           IWDTAGQER++S+   +YRG    LL + + + ++  SL+ W
Sbjct: 147 IWDTAGQERYKSLRTPFYRGTDCCLLTFSVDNLKSLQSLSDW 22
>34597
          Length = 773

 Score = 49.7 bits (117), Expect(2) = 1e-07,   Method: Compositional matrix adjust.
 Identities = 29/94 (30%), Positives = 55/94 (58%), Gaps = 3/94 (3%)
 Frame = -2

Query: 93  RETYNSLAAWLTDARTLASPNIVVILCGNKKDLDPEREVTFLEASRFAQENELMFLETSA 152
           ++++ ++  WL +    A+ ++  ++ GNK D+  +R V+       A+E+ + F+ETSA
Sbjct: 715 KKSFENIVKWLRNIDEHANEDVEKMILGNKCDMTDKRVVSKERGEAIAREHSIRFMETSA 536

Query: 153 LTGENVEEAFLKCARTILNKI---DSGELDPERM 183
            +  N+E AF + A  IL+K    +S E +PER+
Sbjct: 535 KSNINIERAFCELAEAILDKTAGRESAE-NPERV 437

 Score = 22.7 bits (47), Expect(2) = 1e-07,   Method: Compositional matrix adjust.
 Identities = 9/12 (75%), Positives = 10/12 (83%)
 Frame = -3

Query: 76  SYYRGAAGALLV 87
           SYYRGA G +LV
Sbjct: 768 SYYRGAMGIMLV 733
>19656
          Length = 428

 Score = 51.6 bits (122), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 29/99 (29%), Positives = 49/99 (49%), Gaps = 1/99 (1%)
 Frame = +3

Query: 10  KFLVIGSAGTGKSCLLHQFIENKFKQDSNHTIGVEFGSRVVNVGGKTVKLQIWDTAGQER 69
           K +V+G    GK+CLL  +  N F  +   T+   + + V+ V G+ V L +WDTAGQE 
Sbjct: 117 KCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVM-VDGRPVNLGLWDTAGQED 293

Query: 70  FRSVTRSYYRGAAGALLVYDITSRETYNSL-AAWLTDAR 107
           +  +    Y      LL + + S  ++ ++ A W  +  
Sbjct: 294 YDRLRPLSYPQTDVFLLCFSVASPASFENIRAKWYPEVN 410
>14775
          Length = 380

 Score = 50.8 bits (120), Expect = 4e-07,   Method: Compositional matrix adjust.
 Identities = 45/162 (27%), Positives = 66/162 (40%), Gaps = 3/162 (1%)
 Frame = -2

Query: 21  KSCLLHQFIENKFKQDSNHTIGV---EFGSRVVNVGGKTVKLQIWDTAGQERFRSVTRSY 77
           K+CLL ++ +  F   +  TI V   EF     +     V+  +WDT G E +RS+  S+
Sbjct: 379 KTCLLRRYQKGFFMDRTMPTIAVLCSEFNESRTD--PLNVRYTLWDTGGAETYRSLWVSH 206

Query: 78  YRGAAGALLVYDITSRETYNSLAAWLTDARTLASPNIVVILCGNKKDLDPEREVTFLEAS 137
           +RGA  ALLVYD+T                                    ER        
Sbjct: 205 FRGAQVALLVYDVTC-----------------------------------ER------GQ 149

Query: 138 RFAQENELMFLETSALTGENVEEAFLKCARTILNKIDSGELD 179
            FA +    F ETS++TG+NV+  F + A  +     S  L+
Sbjct: 148 AFATQCGYTFFETSSVTGKNVDAVFWEIAFILARLQRSAHLE 23
>08153
          Length = 1703

 Score = 49.3 bits (116), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 33/119 (27%), Positives = 54/119 (45%), Gaps = 3/119 (2%)
 Frame = +1

Query: 10  KFLVIGSAGTGKSCLLHQFIENKFKQDSNHTIGVEFGSRVVNVGGKTVKLQIWDTAGQER 69
           + L++G    GK+ +L+     K K     T     G  V  V  K +   +WD  GQ++
Sbjct: 88  RILMVGLDAAGKTTILY-----KLKLGEIVTTIPTIGFNVETVEYKNISFTVWDVGGQDK 252

Query: 70  FRSVTRSYYRGAAGALLVYDITSRETYNSLAAWLTDARTLASPNI---VVILCGNKKDL 125
            R + R Y++   G + V D   RE  N     L  AR L   ++   ++++  NK+DL
Sbjct: 253 IRPLWRHYFQNTQGLIFVVDSNDRERINEAKEEL--ARMLNEDDLRDAIILVFANKQDL 423
>10708
          Length = 2775

 Score = 38.9 bits (89), Expect(2) = 1e-06,   Method: Compositional matrix adjust.
 Identities = 31/87 (35%), Positives = 37/87 (42%), Gaps = 14/87 (16%)
 Frame = -3

Query: 98   SLAAWLTDARTLASPNIVVILCGNKKDLDPEREVTFLEASRFAQE--------------N 143
            SL  W  + R    PN+ +IL GNKKDL  + E T  E  +  QE              N
Sbjct: 2596 SLKKWTPEVRHFC-PNVPIILVGNKKDLRND-ENTKRELMKMKQEPVRLDEGRAMSEKIN 2423

Query: 144  ELMFLETSALTGENVEEAFLKCARTIL 170
               +LE SA T E V E F    R  L
Sbjct: 2422 AYSYLECSAKTKEGVREVFETATRAAL 2342

 Score = 29.6 bits (65), Expect(2) = 1e-06,   Method: Compositional matrix adjust.
 Identities = 13/46 (28%), Positives = 24/46 (52%)
 Frame = -2

Query: 55   KTVKLQIWDTAGQERFRSVTRSYYRGAAGALLVYDITSRETYNSLA 100
            + V+L +WDTAGQE +  +    Y      L+ + I S ++  ++ 
Sbjct: 2729 QQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIP 2592
>31291
          Length = 446

 Score = 48.5 bits (114), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 39/127 (30%), Positives = 60/127 (47%), Gaps = 14/127 (11%)
 Frame = -1

Query: 59  LQIWDTAGQERFRSVTRSYYRGAAGALLVYDITSRETY-NSLAAWLTDARTLASPNIVVI 117
           LQ+WDTAGQE +  +    Y      +L + + S  +  N    W  + R    P++ ++
Sbjct: 446 LQLWDTAGQEDYDRLRPLAYPNTDVFMLXFSLMSEASMKNVKVKWYPEIRH-HDPHVPIV 270

Query: 118 LCGNKKDLDPERE-VTFLEASR-----FAQENELM-------FLETSALTGENVEEAFLK 164
           L G K DL  ++E V  L +SR       Q N+L        + E S+ T EN++ AF +
Sbjct: 269 LVGTKLDLRQDKEAVRKLRSSRQDPVSSNQGNDLAKAIKAKRYFECSSKTQENLKTAFEE 90

Query: 165 CARTILN 171
             R  LN
Sbjct: 89  TVRVALN 69
>19046
          Length = 445

 Score = 48.5 bits (114), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 33/105 (31%), Positives = 53/105 (50%), Gaps = 2/105 (1%)
 Frame = -2

Query: 67  QERFRSVTRSYYRGAAGALLVYDITSRETYNSLAAWLTDA-RTLASPNIVVILCGNKKDL 125
           QE F ++   Y R   G LLV+ +T   ++ ++A + T   R     +  +ILC NK DL
Sbjct: 444 QEEFSAMREQYMRKGDGFLLVFSVTDFRSFENMANFHTQILRVKDRDSYPMILCANKVDL 265

Query: 126 DPEREVTFLEASRFAQENELMFLETSALTGE-NVEEAFLKCARTI 169
             +R+V+  +    A    + ++ETSA     NV+ AF +  R I
Sbjct: 264 VHQRKVSEEQVRDLATRLRIPYIETSAKDPPLNVDLAFHQVVRVI 130
>24619
          Length = 509

 Score = 46.2 bits (108), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 31/105 (29%), Positives = 51/105 (48%), Gaps = 2/105 (1%)
 Frame = -2

Query: 67  QERFRSVTRSYYRGAAGALLVYDITSRETYNSLAAWLTDA-RTLASPNIVVILCGNKKDL 125
           QE F ++   Y R   G LLV+ +   +++ ++  + T   R        +ILC NK DL
Sbjct: 508 QEEFSAMREQYMRKGDGFLLVFSVIDYQSFENMVNFHTQILRVKDRDTYPMILCANKVDL 329

Query: 126 DPEREVTFLEASRFAQENELMFLETSALTGE-NVEEAFLKCARTI 169
             +R+V+  +    A    + ++ETSA     NV+ AF +  R I
Sbjct: 328 VHQRKVSEEQVRDLATRLRIPYIETSAKDPPLNVDLAFHQVVRVI 194
>09827
          Length = 1201

 Score = 44.7 bits (104), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 32/120 (26%), Positives = 52/120 (43%), Gaps = 3/120 (2%)
 Frame = -3

Query: 9    FKFLVIGSAGTGKSCLLHQFIENKFKQDSNHTIGVEFGSRVVNVGGKTVKLQIWDTAGQE 68
             + L++G    GK+ +L+     K K     T     G  V  V  K +   +WD  GQ+
Sbjct: 1112 MRILMVGLDAAGKTTILY-----KLKLGEIVTTIPTIGFNVETVEYKNISFTVWDVGGQD 948

Query: 69   RFRSVTRSYYRGAAGALLVYDITSRETYNSLAAWLTDARTLASPNI---VVILCGNKKDL 125
            + R + R Y++   G + V D   +E        LT  R L    +   V+++  NK+DL
Sbjct: 947  KIRPLWRHYFQNTQGLIFVVDSNDKERVQEAREELT--RMLNEDELRDAVLLVFANKQDL 774
>33605
          Length = 888

 Score = 43.1 bits (100), Expect = 8e-05,   Method: Compositional matrix adjust.
 Identities = 24/84 (28%), Positives = 38/84 (45%)
 Frame = +1

Query: 10  KFLVIGSAGTGKSCLLHQFIENKFKQDSNHTIGVEFGSRVVNVGGKTVKLQIWDTAGQER 69
           + L++G    GK+ +L      KF  +   TI    G  +  +  +  KL +WD  GQ+ 
Sbjct: 502 RLLMLGLDNAGKTTILK-----KFNGEDIDTISPTLGFNIKTLEHRGFKLNVWDVGGQQS 666

Query: 70  FRSVTRSYYRGAAGALLVYDITSR 93
            RS  R+Y+    G + V D   R
Sbjct: 667 LRSYWRNYFESTDGLVWVVDSADR 738
>10862
          Length = 2896

 Score = 39.7 bits (91), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 21/79 (26%), Positives = 35/79 (44%), Gaps = 4/79 (5%)
 Frame = -3

Query: 51   NVGGKTVKLQIWDTAGQERFRSVTRSYYRGAAGALLVYDITSR----ETYNSLAAWLTDA 106
            N   +  +  +WD  GQ++ R + R YY G  G + V D   R    E    L   + D 
Sbjct: 2504 NCQLQECQFNVWDVGGQDKIRPLWRHYYTGTQGLIFVVDCADRDRIDEARQELHRIINDR 2325

Query: 107  RTLASPNIVVILCGNKKDL 125
                +   ++++  NK+DL
Sbjct: 2324 EMRDA---IILIFANKQDL 2277
>06994
          Length = 429

 Score = 29.6 bits (65), Expect = 1.00,   Method: Compositional matrix adjust.
 Identities = 12/25 (48%), Positives = 17/25 (68%)
 Frame = +3

Query: 9  FKFLVIGSAGTGKSCLLHQFIENKF 33
          +K +V+GS G GKS L  QF++  F
Sbjct: 57 YKLVVLGSGGVGKSALTVQFVQGIF 131
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|39930429|ref|NP_081292.1| translocation protein 1
[Mus musculus]
         (398 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

18887                                                                 143   1e-34
30210                                                                  28   5.2  
>18887
          Length = 1160

 Score =  143 bits (360), Expect = 1e-34,   Method: Compositional matrix adjust.
 Identities = 65/108 (60%), Positives = 81/108 (75%), Gaps = 1/108 (0%)
 Frame = -2

Query: 174 DDQVFLDGNE-VFVWIYDPVHIKTFVMGLILVIAVIAATLFPLWPAEMRVGVYYLSVGAG 232
           DDQ F+DG E ++VW+YDP + KT ++G ++V+  IA  LFPLWP  +R+GVYY+S+ A 
Sbjct: 688 DDQRFIDGEENIYVWVYDPANAKTLIIGTLIVLGAIALCLFPLWPEIVRLGVYYVSLAAA 509

Query: 233 CFVASILLLAIARCILFLIIWLITGGRHHFWFLPNLTADVGFIDSFRP 280
            FV  IL L + R ILF +IWLIT GRHHFW LPNLT DVGF DSFRP
Sbjct: 508 SFVGFILGLVVLRLILFCLIWLITLGRHHFWLLPNLTEDVGFFDSFRP 365

 Score = 54.3 bits (129), Expect = 9e-08,   Method: Compositional matrix adjust.
 Identities = 24/50 (48%), Positives = 33/50 (66%)
 Frame = -2

Query: 44   VDYFIASKAVECLLDSKWAKAKKGEDALFTTRESVVDYCNRLLKKQFFHR 93
            V  F AS A++ L+ SKW+ AK  ++ LF  R+S V YC RL++K  FHR
Sbjct: 1135 VHCFYASAAIDALMTSKWSAAKNAKEPLFYNRQSCVFYCQRLMQKGIFHR 986
>30210
          Length = 435

 Score = 28.5 bits (62), Expect = 5.2,   Method: Compositional matrix adjust.
 Identities = 12/30 (40%), Positives = 17/30 (56%)
 Frame = +3

Query: 187 WIYDPVHIKTFVMGLILVIAVIAATLFPLW 216
           W+YD VHI  ++  L   I V A TL  ++
Sbjct: 177 WMYDCVHISIYMCALYTYICVYANTLVDMY 266
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|10946936|ref|NP_067490.1| adenylate kinase 1 [Mus
musculus]
         (210 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

06512                                                                 141   2e-34
01182                                                                 138   2e-33
16252                                                                  95   2e-20
30736                                                                  29   1.6  
03659                                                                  27   4.3  
>06512
          Length = 2288

 Score =  141 bits (356), Expect = 2e-34,   Method: Compositional matrix adjust.
 Identities = 73/198 (36%), Positives = 121/198 (61%), Gaps = 4/198 (2%)
 Frame = +1

Query: 14   GRKTGEKLKKAKIIFVVGGPGSGKGTQCEKIVQKY-GYTHLSTGDLLRAEVS---SGSER 69
            GRK    + KA IIF  GGP SGKGTQC++++ +Y    HLS GD++RA+++   S  ++
Sbjct: 1090 GRKPD--MPKAPIIFFAGGPASGKGTQCKRLLSRYTNAAHLSMGDIIRAQIATQGSADDK 1263

Query: 70   GKKLSAIMEKGELVPLDTVLDMLRDAMLAKVDSSNGFLIDGYPREVKQGEEFEQKIGQPT 129
               ++ +M KGEL P +  +D+L  ++ ++ D+ + +L++GYPR ++Q E+F QKIG  +
Sbjct: 1264 WDMMTDLMRKGELAPEEVTVDLLMSSLKSQPDA-HFYLVEGYPRNLQQLEDFNQKIGGQS 1440

Query: 130  LLLYVDAGAETMTQRLLKRGETSGRVDDNEETIKKRLETYYNATEPVISFYDKRGIVRKV 189
              + +D   + +  RL  RG+TS R+DDN   I K+L  + N T P++  +D  G +  V
Sbjct: 1441 FTILLDCEEDILHYRLTMRGKTSERIDDNLVAIGKKLTYFKNNTLPILKTFDDSGKLVVV 1620

Query: 190  NAEGTVDTVFSEVCTYLD 207
              +   D +F ++C  LD
Sbjct: 1621 GGDRDEDEIFFDLCKVLD 1674

 Score =  133 bits (334), Expect = 7e-32,   Method: Compositional matrix adjust.
 Identities = 68/193 (35%), Positives = 114/193 (59%), Gaps = 4/193 (2%)
 Frame = +1

Query: 21  LKKAKIIFVVGGPGSGKGTQCEKIVQKYG-YTHLSTGDLLRAEVS---SGSERGKKLSAI 76
           +    IIF+ GGPGSGK TQ E ++QKY  +  +  GDLLR E++   SG+ R K +S +
Sbjct: 316 IPDVPIIFLTGGPGSGKSTQAELLLQKYPKWVTVPVGDLLRQEINDNGSGNARWKMVSEL 495

Query: 77  MEKGELVPLDTVLDMLRDAMLAKVDSSNGFLIDGYPREVKQGEEFEQKIGQPTLLLYVDA 136
           M  GE+VP D V  +L D  L     + GF+I G+PR+++Q E++E+ +G+   +  +D 
Sbjct: 496 MSDGEMVPEDVVDTLLLDK-LKSAPKAEGFVIQGFPRDMEQAEQYEKLVGRVDAVFLIDC 672

Query: 137 GAETMTQRLLKRGETSGRVDDNEETIKKRLETYYNATEPVISFYDKRGIVRKVNAEGTVD 196
             ET++Q+LL R +++ R+D+N  T+ KR+  + + T PV+  +D    +  +N E    
Sbjct: 673 EEETLSQQLLDRAKSTKRIDNNVNTVAKRIHAFRDNTLPVLKHFDDMEKLFVLNGESPAK 852

Query: 197 TVFSEVCTYLDSL 209
            V  E+    +++
Sbjct: 853 AVAEELAIIFETV 891
>01182
          Length = 2762

 Score =  138 bits (348), Expect = 2e-33,   Method: Compositional matrix adjust.
 Identities = 70/196 (35%), Positives = 118/196 (60%), Gaps = 4/196 (2%)
 Frame = -3

Query: 18   GEKLKKAKIIFVVGGPGSGKGTQCEKIVQKYGYTHLSTGDLLRAEVSSGSERGK-KLSAI 76
            G+  +   ++FV+GGPG+GKGTQC KI + +GY HLS GDLLRAE +    + K ++   
Sbjct: 2316 GDSAQMYNVVFVLGGPGAGKGTQCTKIEETFGYKHLSAGDLLRAERAKEESKFKDEIETH 2137

Query: 77   MEKGELVPLDTVLDMLRDAMLAKVDSSNGFLIDGYPREVKQGEEFEQKIGQPTLL---LY 133
            ++ G +VP++    +L+ AM  +    + FLIDG+PR     + + + +    ++   L+
Sbjct: 2136 IKNGSIVPVEITCSLLKQAM--EESRKDKFLIDGFPRNKNNLDGWNKVMDSVAVVRKVLF 1963

Query: 134  VDAGAETMTQRLLKRGETSGRVDDNEETIKKRLETYYNATEPVISFYDKRGIVRKVNAEG 193
             +   +    R L RG+ SGR DDN E+++KR++TY  +T P+I  Y K+ +V ++NA  
Sbjct: 1962 FNCPEDVCIDRCLDRGKNSGRADDNRESLEKRIKTYTESTMPIIEHYKKQSLVAEINANQ 1783

Query: 194  TVDTVFSEVCTYLDSL 209
            T + VF++V    ++L
Sbjct: 1782 TEEQVFNDVTKVFNTL 1735
>16252
          Length = 789

 Score = 95.1 bits (235), Expect = 2e-20,   Method: Compositional matrix adjust.
 Identities = 62/180 (34%), Positives = 98/180 (54%), Gaps = 33/180 (18%)
 Frame = +2

Query: 56  GDLLRAEVSSGSERGKKLSAIMEKGELVPLDTVLDMLRDAMLAKVDSSNGFLIDGYPREV 115
           GD+LRAE+SSGS+ G +L  +M++G+LV  D V++M+ D+ L K +  NGFL+DG+PR V
Sbjct: 2   GDMLRAEISSGSKLGSELKKVMDEGKLVSDDLVVNMI-DSNLDKPECKNGFLLDGFPRTV 178

Query: 116 KQGEEFEQKIGQPTLLLYVDAGAE----------TMTQRLLK------------------ 147
            Q ++ +  + +     ++DA  E           +T RL+                   
Sbjct: 179 VQAQKLDSLLDKRK--THLDAVIEFAIDDNLLVRRITGRLIHQASGRSYHEEFAPPKVPM 352

Query: 148 RGETSG-----RVDDNEETIKKRLETYYNATEPVISFYDKRGIVRKVNAEGTVDTVFSEV 202
           R + +G     R DDN E +KKRLE+Y+  T+P++ +Y  RG+  KV+A      VFS +
Sbjct: 353 RDDITGELLMKRSDDNAEALKKRLESYHKQTKPLVDYYGLRGLHFKVDAAKQASDVFSTI 532
>30736
          Length = 520

 Score = 28.9 bits (63), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 12/36 (33%), Positives = 20/36 (55%)
 Frame = -2

Query: 29  VVGGPGSGKGTQCEKIVQKYGYTHLSTGDLLRAEVS 64
           V+G P SGK T C  +  KYG   L   ++++  ++
Sbjct: 108 VLGPPLSGKTTLCHLLANKYGAKVLKVEEIIKPRMA 1
>03659
          Length = 1566

 Score = 27.3 bits (59), Expect = 4.3,   Method: Compositional matrix adjust.
 Identities = 12/27 (44%), Positives = 18/27 (66%)
 Frame = -1

Query: 25  KIIFVVGGPGSGKGTQCEKIVQKYGYT 51
           +I+ V+G  GSGK TQ  + + + GYT
Sbjct: 468 QILIVIGETGSGKTTQITQYLAESGYT 388
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|18017605|ref|NP_542127.1| ubiquitin-conjugating
enzyme E2N [Mus musculus]
         (152 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

21443                                                                 140   2e-34
31099                                                                 134   1e-32
37111                                                                 122   7e-29
02740                                                                 115   8e-27
18592                                                                  97   2e-21
34525                                                                  95   1e-20
02313                                                                  91   2e-19
19311                                                                  91   2e-19
14380                                                                  89   9e-19
12485                                                                  86   6e-18
04905                                                                  85   1e-17
38163                                                                  73   4e-14
02183                                                                  73   5e-14
13254                                                                  65   1e-11
05633                                                                  61   2e-10
39424                                                                  60   3e-10
20166                                                                  49   1e-06
34541                                                                  40   4e-06
21560                                                                  45   1e-05
10963                                                                  39   0.001
26740                                                                  39   0.001
29762                                                                  31   0.003
>21443
          Length = 610

 Score =  140 bits (353), Expect = 2e-34,   Method: Compositional matrix adjust.
 Identities = 68/144 (47%), Positives = 90/144 (62%)
 Frame = -1

Query: 6   RRIIKETQRLLAEPVPGIKAEPDESNARYFHVVIAGPQDSPFEGGTFKLELFLPEEYPMA 65
           +RI KE Q L  +P     A P   +   +   I GP+DS +EGG F L +  P +YP  
Sbjct: 526 KRINKELQDLGKDPPAQCSAGPVGEDMFQWQATIMGPRDSAYEGGVFFLTISFPTDYPFK 347

Query: 66  APKVRFMTKIYHPNVDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPDDPLANDV 125
            PKV F T+IYHPN++  G ICLDIL+ +WSPAL I  VLLSI ++L+ PNPDDPL  ++
Sbjct: 346 PPKVSFTTRIYHPNINSNGSICLDILRSQWSPALTISKVLLSICSMLTDPNPDDPLVPEI 167

Query: 126 AEQWKTNEAQAIETARAWTRLYAM 149
           A  +KT+  +  E A+ WT  YAM
Sbjct: 166 ARIYKTDREKFYENAKIWTNKYAM 95
>31099
          Length = 748

 Score =  134 bits (337), Expect = 1e-32,   Method: Compositional matrix adjust.
 Identities = 64/144 (44%), Positives = 88/144 (61%)
 Frame = +2

Query: 6   RRIIKETQRLLAEPVPGIKAEPDESNARYFHVVIAGPQDSPFEGGTFKLELFLPEEYPMA 65
           + + KE Q L  +P     A P   +  ++   I GP  SP++GG F L +  P +YP  
Sbjct: 101 KDLQKELQDLGRDPPANCSAGPVGDDFFHWQATIMGPNKSPYQGGVFFLTITFPADYPFK 280

Query: 66  APKVRFMTKIYHPNVDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPDDPLANDV 125
            PKV F TKIYHPN++  G ICLDIL+ +WSPAL I  VLLSI +LL+ PNPDDPL  ++
Sbjct: 281 PPKVAFTTKIYHPNINSNGSICLDILRSQWSPALTISKVLLSISSLLTDPNPDDPLVPEI 460

Query: 126 AEQWKTNEAQAIETARAWTRLYAM 149
           A  +K +  +  +  + WT+ YAM
Sbjct: 461 ARVYKNDRHKYEQLGKEWTQKYAM 532
>37111
          Length = 611

 Score =  122 bits (305), Expect = 7e-29,   Method: Compositional matrix adjust.
 Identities = 58/111 (52%), Positives = 80/111 (72%), Gaps = 1/111 (0%)
 Frame = -1

Query: 39  IAGPQDSPFEGGTFKLELFLPEEYPMAAPKVRFMTKIYHPNVDKL-GRICLDILKDKWSP 97
           I GP ++P+EGG F+L++ +PE YP   P V+F+TKI+HPNV  + G ICLDILKD+W+ 
Sbjct: 377 IMGPPETPYEGGRFELDIRIPETYPFNPPLVKFLTKIWHPNVSSVTGAICLDILKDQWAA 198

Query: 98  ALQIRTVLLSIQALLSAPNPDDPLANDVAEQWKTNEAQAIETARAWTRLYA 148
           A+ +RTVLLS+QAL++A  PDDP    VA Q+K +     +TAR WT  +A
Sbjct: 197 AMTLRTVLLSLQALMAAAEPDDPQDAVVANQYKDHRELFNKTARHWTSAFA 45
>02740
          Length = 2287

 Score =  115 bits (288), Expect = 8e-27,   Method: Compositional matrix adjust.
 Identities = 59/129 (45%), Positives = 76/129 (58%)
 Frame = -1

Query: 6    RRIIKETQRLLAEPVPGIKAEPDESNARYFHVVIAGPQDSPFEGGTFKLELFLPEEYPMA 65
            +R+ +E + L+    PG+ A PD  N   +   I G + + +EG  +KL L  P  YP  
Sbjct: 1996 KRLQQELRTLMMSSDPGVSAFPDGDNLFKWVGTIEGAKGTVYEGLQYKLVLEFPSGYPYQ 1817

Query: 66   APKVRFMTKIYHPNVDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPDDPLANDV 125
            A  VRF T  +HPNVD  G ICLDILK+KWS    +RTVLLSIQ+LL+ PN   PL    
Sbjct: 1816 AVSVRFSTPCFHPNVDNHGNICLDILKEKWSALYDVRTVLLSIQSLLAEPNNVSPLNXHA 1637

Query: 126  AEQWKTNEA 134
            AE WK  +A
Sbjct: 1636 AELWKNQDA 1610
>18592
          Length = 475

 Score = 97.1 bits (240), Expect = 2e-21,   Method: Compositional matrix adjust.
 Identities = 53/128 (41%), Positives = 79/128 (61%), Gaps = 4/128 (3%)
 Frame = +2

Query: 6   RRIIKETQRLLAEPVPG---IKAEPDESNARYFHVVIAGPQDSPFEGGTFKLELFLPEEY 62
           RR+ KE Q +  E       IK + DESN  ++ VV+  P++ P+  GTF +++  P EY
Sbjct: 98  RRLTKELQDIRKEASQKAFRIKDQ-DESNILHWEVVLV-PENPPYNKGTFTVDINFPAEY 271

Query: 63  PMAAPKVRFMTKIYHPNVDKLGRICLDILK-DKWSPALQIRTVLLSIQALLSAPNPDDPL 121
           P   PKV F TKIYHPNVD+ G++CL I+  + W PA +   VL ++  L++ P P+ PL
Sbjct: 272 PFKPPKVTFKTKIYHPNVDEKGQVCLPIISAENWKPATKTDQVLTALIGLINEPEPEHPL 451

Query: 122 ANDVAEQW 129
             D+AE++
Sbjct: 452 RADLAEEY 475
>34525
          Length = 561

 Score = 95.1 bits (235), Expect = 1e-20,   Method: Compositional matrix adjust.
 Identities = 47/110 (42%), Positives = 65/110 (59%), Gaps = 4/110 (3%)
 Frame = -1

Query: 47  FEGGTFKLELFLPEEYPMAAPKVRFMTKIYHPNVDKLGRICLDIL----KDKWSPALQIR 102
           F+G      L LPE YP   PKV+F T IYHPN+D  GRICLD L    K  W P + + 
Sbjct: 393 FQGS----HLILPERYPFEPPKVQFTTPIYHPNIDNAGRICLDTLKMPPKGAWKPCMNLM 226

Query: 103 TVLLSIQALLSAPNPDDPLANDVAEQWKTNEAQAIETARAWTRLYAMNNI 152
           TVL S+Q L++ PNPDD L  D+A ++K       + A  +T+ +A +++
Sbjct: 225 TVLTSLQLLMATPNPDDALMADIASEFKHTPELFRQKAVQFTKQHAYDSV 76
>02313
          Length = 891

 Score = 90.9 bits (224), Expect = 2e-19,   Method: Compositional matrix adjust.
 Identities = 50/145 (34%), Positives = 79/145 (54%), Gaps = 17/145 (11%)
 Frame = -1

Query: 11  ETQRLLAEPVPGIKAE-PDESNARYFHVVIAGPQDSPFEGGTFKLELFLPEEYPMAAPKV 69
           E +++ AEPV G + +  ++ N   + V I GP  + +EGG FK  +  P +YP + P V
Sbjct: 744 ELKKIQAEPVEGFRVKLINDDNIFEWEVAIFGPPGTLYEGGYFKAHMKFPADYPYSPPSV 565

Query: 70  RFMTKIYHPNVDKLGRICLDIL-------------KDKWSPALQIRTVLLSIQALLSAPN 116
           RF+TK++HPNV + G +C+ IL              ++W+P   +RT+LLSI +LL+ PN
Sbjct: 564 RFITKMWHPNVYENGEVCISILHPPVDDPQSGELPSERWNPTQTVRTILLSIISLLNEPN 385

Query: 117 PDDPLANDVA---EQWKTNEAQAIE 138
              P   D +    +WK    +  E
Sbjct: 384 TYSPANVDASVMYRKWKDTXGKEKE 310
>19311
          Length = 1071

 Score = 90.9 bits (224), Expect = 2e-19,   Method: Compositional matrix adjust.
 Identities = 52/146 (35%), Positives = 78/146 (53%)
 Frame = -2

Query: 6   RRIIKETQRLLAEPVPGIKAEPDESNARYFHVVIAGPQDSPFEGGTFKLELFLPEEYPMA 65
           RR+  E + L ++P  GI+A               GP+    +GG F L L +P  YPM 
Sbjct: 590 RRLRSELKTLKSDPPEGIQATHWTGTVATGRPPSQGPRAVRXKGGWFLLYLQIPHSYPMR 411

Query: 66  APKVRFMTKIYHPNVDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPDDPLANDV 125
            PKVRF+TKI+HPN+ + G + LD +   WS AL I  VL+SIQ++L+ P     +   +
Sbjct: 410 PPKVRFITKIFHPNISRHGDVGLDSIHHNWSLALTISKVLISIQSVLTDPYCHVCMEPKI 231

Query: 126 AEQWKTNEAQAIETARAWTRLYAMNN 151
              ++  + +    AR WT  YAM++
Sbjct: 230 GALYQRAKPEFERIARRWTWKYAMHD 153
>14380
          Length = 1522

 Score = 88.6 bits (218), Expect = 9e-19,   Method: Compositional matrix adjust.
 Identities = 44/133 (33%), Positives = 70/133 (52%)
 Frame = +3

Query: 16  LAEPVPGIKAEPDESNARYFHVVIAGPQDSPFEGGTFKLELFLPEEYPMAAPKVRFMTKI 75
           L E   G K   ++ +       I GP  +P+ GG F+++L L + +P   PK  F+TKI
Sbjct: 150 LPECARGNKIFTNDEDITDIQATIEGPAGTPYAGGLFRMKLVLSKSFPSEPPKAFFITKI 329

Query: 76  YHPNVDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPDDPLANDVAEQWKTNEAQ 135
           +HPNV   G IC++ LK  W P L I+ +LL+++ LL  PNP+  L  +  +        
Sbjct: 330 FHPNVASNGEICVNTLKRDWKPELGIKHILLTVKCLLIVPNPESALNEEAGKLLLEQYED 509

Query: 136 AIETARAWTRLYA 148
               A+ +T ++A
Sbjct: 510 YSMRAKMFTEIHA 548
>12485
          Length = 652

 Score = 85.9 bits (211), Expect = 6e-18,   Method: Compositional matrix adjust.
 Identities = 39/94 (41%), Positives = 59/94 (62%), Gaps = 2/94 (2%)
 Frame = +1

Query: 35  FHVVIAGPQDSPFEGGTFKLELFLPEEYPMAAPKVRFMTKIYHPNVDKL-GRICLDILKD 93
           F V   GP  +P+EGG +K+ + LPE+YP  +P + FM +IYHPN+D++ G +CLD++  
Sbjct: 13  FLVKFYGPPSTPYEGGVWKVRVDLPEKYPFKSPSIGFMNRIYHPNIDEVSGTVCLDVINQ 192

Query: 94  KWSPALQIRTVLLS-IQALLSAPNPDDPLANDVA 126
            W+    +  +  S +  LL+ PNP DPL  D A
Sbjct: 193 AWTALYDLSNIFESFLPQLLTYPNPIDPLNGDAA 294
>04905
          Length = 1868

 Score = 84.7 bits (208), Expect = 1e-17,   Method: Compositional matrix adjust.
 Identities = 38/94 (40%), Positives = 58/94 (61%), Gaps = 2/94 (2%)
 Frame = -1

Query: 35   FHVVIAGPQDSPFEGGTFKLELFLPEEYPMAAPKVRFMTKIYHPNVDKL-GRICLDILKD 93
            F V   GP  +P+EGG +K+ + LPE YP  +P + F+ +IYHPN+D++ G +CLD++  
Sbjct: 1682 FTVKFFGPPSTPYEGGVWKVRVDLPERYPFKSPSIGFINRIYHPNIDEVSGTVCLDVINQ 1503

Query: 94   KWSPALQIRTVLLS-IQALLSAPNPDDPLANDVA 126
             W+    +  +  S +  LL+ PNP DPL  D A
Sbjct: 1502 AWTALYDLSNIFESFLPQLLTYPNPVDPLNGDAA 1401
>38163
          Length = 2214

 Score = 73.2 bits (178), Expect = 4e-14,   Method: Compositional matrix adjust.
 Identities = 37/106 (34%), Positives = 57/106 (53%), Gaps = 2/106 (1%)
 Frame = -3

Query: 39   IAGPQDSPFEGGTFKLELFLPEEYPMAAPKVRFMTKIYHPNVDKLGRICLDILKDK--WS 96
            I G + + +EGG F L +   E+YP   PK +F   ++HPNV   G +CL +L ++  W 
Sbjct: 1654 IPGKKGTMWEGGLFSLRMLFKEDYPSTPPKCKFEPPLFHPNVYPSGTVCLSLLDEEKDWR 1475

Query: 97   PALQIRTVLLSIQALLSAPNPDDPLANDVAEQWKTNEAQAIETARA 142
            PA+ I+ +LL IQ LL+  N  DP   +    +  N ++     RA
Sbjct: 1474 PAVTIKQILLGIQELLNECNVKDPAQAEAYTIYCQNSSEYERRVRA 1337
>02183
          Length = 1456

 Score = 72.8 bits (177), Expect = 5e-14,   Method: Compositional matrix adjust.
 Identities = 41/148 (27%), Positives = 75/148 (50%), Gaps = 7/148 (4%)
 Frame = -2

Query: 8    IIKETQRLLAEPVPGIKAEPDESNARYFHVVIAGPQDSPFEGGTFKLELFLPEEYPMAAP 67
            ++KE Q +        K + D+ +  +  ++   P +  + GG FK ++ +PEEY +  P
Sbjct: 1278 LVKEVQEMEENMPRTCKVQFDDPSVLHHFILNVTPDEGYWTGGKFKFDINVPEEYNIVPP 1099

Query: 68   KVRFMTKIYHPNVDKLGRICLDILKDK------WSPALQIRTVLLSIQALLSA-PNPDDP 120
            K    TKI+HPN+ + G ICL +L+        W+P  +++ V+  + +L S   N +DP
Sbjct: 1098 KAVCHTKIWHPNITEAGEICLSLLRQNSYDGLGWAPTRRLKDVVWGLNSLFSDLLNFEDP 919

Query: 121  LANDVAEQWKTNEAQAIETARAWTRLYA 148
            L  + AE +  ++       R + + YA
Sbjct: 918  LNVEAAEHFARDKESFKIKVRDYIQAYA 835
>13254
          Length = 870

 Score = 64.7 bits (156), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 32/83 (38%), Positives = 46/83 (55%)
 Frame = +2

Query: 66  APKVRFMTKIYHPNVDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPDDPLANDV 125
           A K  F+TKI+HPNV   G IC++ LK  W P L I+ +LL+I+ LL  PNP+  L  + 
Sbjct: 167 AAKGIFLTKIFHPNVASNGEICVNTLKKDWKPDLGIKHILLTIKCLLIVPNPESALNEEA 346

Query: 126 AEQWKTNEAQAIETARAWTRLYA 148
            +          + AR  T ++A
Sbjct: 347 GKMLLERYDDYSQRARMMTEIHA 415
>05633
          Length = 1150

 Score = 61.2 bits (147), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 31/80 (38%), Positives = 47/80 (58%), Gaps = 2/80 (2%)
 Frame = +3

Query: 37  VVIAGPQDSPFEGGTFKLELFLPEEYPMAAPKVRFMTKIY--HPNVDKLGRICLDILKDK 94
           V + G   + +EG  F+L      +YP  +P+V F+      HP+V   G ICL IL + 
Sbjct: 51  VDLEGATGTLYEGEKFQLHFKFGAKYPFDSPQVTFLGPNIPIHPHVYSNGHICLSILTED 230

Query: 95  WSPALQIRTVLLSIQALLSA 114
           WSPAL +++V LSI ++LS+
Sbjct: 231 WSPALSVQSVCLSIVSMLSS 290
>39424
          Length = 1749

 Score = 60.5 bits (145), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 28/94 (29%), Positives = 52/94 (55%), Gaps = 13/94 (13%)
 Frame = -2

Query: 50   GTFKLELFLPEEYPMAAPKVRFMTKIYHPNVDKLGRICLDIL-------------KDKWS 96
             T KL    P+  P+  PK++F+++++HPN+D  G +C+ IL              ++W 
Sbjct: 1541 ATSKLI*SSPKNIPIGRPKMKFVSEMWHPNIDPEGNVCISILHEPGDDKYGYEKASERWL 1362

Query: 97   PALQIRTVLLSIQALLSAPNPDDPLANDVAEQWK 130
            P   + T+L+S+ ++L+ PN + P   D A+ W+
Sbjct: 1361 PIHTVETILVSVISMLADPNDESPANVDAAKMWR 1260

 Score = 38.1 bits (87), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 17/41 (41%), Positives = 25/41 (60%)
 Frame = -1

Query: 28   DESNARYFHVVIAGPQDSPFEGGTFKLELFLPEEYPMAAPK 68
            D+ +   + V+I GP ++ F+GG FK  L  P+EYP   PK
Sbjct: 1608 DDDDVYKWEVLIYGPPETLFDGGYFKAHLIFPKEYPNRPPK 1486
>20166
          Length = 446

 Score = 48.5 bits (114), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 27/91 (29%), Positives = 43/91 (47%), Gaps = 2/91 (2%)
 Frame = +1

Query: 28  DESNARYFHVVIAGPQDSPFEGGTFKLELFLPEEYPMAAPKVRFMTKIYHPNVDKLGRIC 87
           D+ N   +   I GP  +P+EG  + L +  P  YP   P VRF TKI    V+  G + 
Sbjct: 34  DDRNLESWQGTIIGPMKTPYEGRIYTLRMSCPMSYPRHPPSVRFETKINLSCVEDNGTVD 213

Query: 88  LDILKDK--WSPALQIRTVLLSIQALLSAPN 116
           L  L  K  W     ++ +L  I+  +++ +
Sbjct: 214 LKRLGRKFAWDSNTTLKVILEEIRNCMASKD 306
>34541
          Length = 491

 Score = 40.0 bits (92), Expect(2) = 4e-06,   Method: Compositional matrix adjust.
 Identities = 15/33 (45%), Positives = 21/33 (63%)
 Frame = +2

Query: 84  GRICLDILKDKWSPALQIRTVLLSIQALLSAPN 116
           G ICLDIL+++WSP   +  +L SIQ   + P 
Sbjct: 59  GSICLDILQNRWSPTYDVSAILTSIQLCFTTPT 157

 Score = 26.2 bits (56), Expect(2) = 4e-06,   Method: Compositional matrix adjust.
 Identities = 14/38 (36%), Positives = 20/38 (52%)
 Frame = +1

Query: 110 ALLSAPNPDDPLANDVAEQWKTNEAQAIETARAWTRLY 147
           ALL  PNP+ P  N+ A+ ++ N     E  + W  LY
Sbjct: 136 ALLHDPNPNSPANNEAAQLFRENRR---EYEKRWRPLY 240
>21560
          Length = 418

 Score = 45.1 bits (105), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 20/22 (90%), Positives = 22/22 (100%)
 Frame = +3

Query: 131 TNEAQAIETARAWTRLYAMNNI 152
           TNEAQAIETARAWTRLYA+NN+
Sbjct: 3   TNEAQAIETARAWTRLYALNNM 68
>10963
          Length = 569

 Score = 38.5 bits (88), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 16/30 (53%), Positives = 21/30 (70%)
 Frame = +3

Query: 64  MAAPKVRFMTKIYHPNVDKLGRICLDILKD 93
            A  +V F T+IYH N++  G ICLDILK+
Sbjct: 474 FANVQVVFKTRIYHCNINSQGAICLDILKE 563
>26740
          Length = 404

 Score = 38.5 bits (88), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 20/67 (29%), Positives = 33/67 (49%), Gaps = 11/67 (16%)
 Frame = +2

Query: 12  TQRLLAEPVPGIKAEPDESNARYF-----------HVVIAGPQDSPFEGGTFKLELFLPE 60
           T+RL  E V    + P   N+  F            V+I GP D+P+  G F+ +++ P+
Sbjct: 191 TRRLAQEAVTLSTSLPLSYNSSVFVRCDDERLDIMKVLITGPSDTPYANGAFEFDVYFPQ 370

Query: 61  EYPMAAP 67
           +YP + P
Sbjct: 371 DYPNSPP 391
>29762
          Length = 460

 Score = 31.2 bits (69), Expect(2) = 0.003,   Method: Compositional matrix adjust.
 Identities = 9/26 (34%), Positives = 18/26 (69%)
 Frame = -2

Query: 84  GRICLDILKDKWSPALQIRTVLLSIQ 109
           G +CL+IL++ W P L + +++  +Q
Sbjct: 426 GNVCLNILREDWKPVLTVNSIVYGLQ 349

 Score = 25.0 bits (53), Expect(2) = 0.003,   Method: Compositional matrix adjust.
 Identities = 10/18 (55%), Positives = 13/18 (72%)
 Frame = -1

Query: 115 PNPDDPLANDVAEQWKTN 132
           PNP+DPL  + AE  +TN
Sbjct: 334 PNPEDPLNKEAAEVLQTN 281
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|18390323|ref|NP_080973.1| RAB14, member RAS oncogene
family [Mus musculus]
         (215 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

08428                                                                 141   2e-34
01398                                                                 133   6e-32
33374                                                                 120   7e-31
34468                                                                 123   6e-29
14456                                                                 111   2e-25
17511                                                                 102   1e-22
26083                                                                  99   9e-22
05468                                                                  98   2e-21
01095                                                                  97   4e-21
07465                                                                  97   7e-21
33794                                                                  95   2e-20
30760                                                                  92   1e-19
13901                                                                  90   9e-19
33380                                                                  89   1e-18
13750                                                                  86   1e-17
01972                                                                  83   7e-17
11257                                                                  81   1e-16
29380                                                                  81   2e-16
07580                                                                  80   5e-16
32723                                                                  80   7e-16
35581                                                                  79   1e-15
26536                                                                  75   2e-14
12339                                                                  70   5e-13
27191                                                                  69   2e-12
14119                                                                  69   2e-12
19006                                                                  68   3e-12
13745                                                                  65   2e-11
11728                                                                  65   2e-11
00858                                                                  62   2e-10
34359                                                                  62   2e-10
25618                                                                  61   4e-10
09204                                                                  55   3e-08
14775                                                                  55   3e-08
00552                                                                  54   4e-08
10708                                                                  42   6e-08
19656                                                                  50   5e-07
34597                                                                  50   6e-07
08153                                                                  48   3e-06
31291                                                                  44   3e-05
09827                                                                  44   5e-05
18509                                                                  43   1e-04
25796                                                                  42   1e-04
10862                                                                  42   1e-04
33605                                                                  42   2e-04
32770                                                                  30   0.69 
>08428
          Length = 1109

 Score =  141 bits (356), Expect = 2e-34,   Method: Compositional matrix adjust.
 Identities = 67/160 (41%), Positives = 100/160 (62%)
 Frame = -3

Query: 13   KYIIIGDMGVGKSCLLHQFTEKKFMADCPHTIGVEFGTRIIEVSGQKIKLQIWDTAGQER 72
            K  ++GD GVGKS ++ +F    +      TIG  F ++ + V G   + QIWDTAGQE+
Sbjct: 1065 KVCLLGDSGVGKSSIVLRFVTGSYRPSQESTIGASFMSKSLVVDGAGYRFQIWDTAGQEK 886

Query: 73   FRAVTRSYYRGAAGALMVYDITRRSTYNHLSSWLTDARNLTNPNTVIILIGNKADLEAQR 132
            FRA+   YYRGAA A++VYD+TR  T+  + SW+ + R+   PN V+ + GNK DLE  R
Sbjct: 885  FRALAPMYYRGAAAAVIVYDVTRPRTFKSVKSWIQELRSFGPPNIVLAIAGNKCDLEELR 706

Query: 133  DVTYEEAKQFAEENGLLFLEASAKTGENVEDAFLEAAKKI 172
            +V  ++A+++A     +F E SA T  NVE+ F E A+++
Sbjct: 705  EVVEKDAQEYASSISAIFGETSAMTAVNVEEMFTELARQL 586
>01398
          Length = 1421

 Score =  133 bits (334), Expect = 6e-32,   Method: Compositional matrix adjust.
 Identities = 67/147 (45%), Positives = 91/147 (61%), Gaps = 1/147 (0%)
 Frame = -2

Query: 70   QERFRAVTRSYYRGAAGALMVYDITRRSTYNHLSSWLTDARNLTNPNTVIILI-GNKADL 128
            QERFR++TRSYYR + G ++VYDIT+RST+ +L  W  +ARN   P+  I L+ G+K+D 
Sbjct: 1420 QERFRSITRSYYRNSVGVIIVYDITKRSTFENLKQWYEEARNHIEPHKAIFLVLGHKSDR 1241

Query: 129  EAQRDVTYEEAKQFAEENGLLFLEASAKTGENVEDAFLEAAKKIYQNIQDGSLDLNAAES 188
            E  R VT  E ++FAE +GL F E SAK+G N+ED F + AK  YQ++QDG + L     
Sbjct: 1240 EDARQVTAREGRRFAEMHGLKFFETSAKSGHNIEDVFAQIAKDTYQHLQDGHIRLEEGWD 1061

Query: 189  GVQHKPSAPQGGRLTSEPQPQREGCGC 215
            GV+   + P   R T       E  GC
Sbjct: 1060 GVKQGFARP---RETVHLAEGEESGGC 989
>33374
          Length = 489

 Score =  120 bits (300), Expect(2) = 7e-31,   Method: Compositional matrix adjust.
 Identities = 56/116 (48%), Positives = 78/116 (67%)
 Frame = +1

Query: 48  FGTRIIEVSGQKIKLQIWDTAGQERFRAVTRSYYRGAAGALMVYDITRRSTYNHLSSWLT 107
           F T+ + +    +K +IWDTAGQER+ ++   YYRGA  A++VYDIT + T+    +W+ 
Sbjct: 139 FLTQTVCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNQDTFGRAKTWVK 318

Query: 108 DARNLTNPNTVIILIGNKADLEAQRDVTYEEAKQFAEENGLLFLEASAKTGENVED 163
           + +   +PN VI L GNKADL  +R V +EEA+ +AEEN LLF+E SAKT  NV D
Sbjct: 319 ELQRQASPNIVIALAGNKADLANKRMVEFEEAQAYAEENSLLFMETSAKTAMNVND 486

 Score = 30.8 bits (68), Expect(2) = 7e-31,   Method: Compositional matrix adjust.
 Identities = 15/40 (37%), Positives = 23/40 (57%)
 Frame = +2

Query: 12 FKYIIIGDMGVGKSCLLHQFTEKKFMADCPHTIGVEFGTR 51
          FK +++G+  VGKS L+ +F + +F      TIG  F  R
Sbjct: 32 FKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAF*LR 151
>34468
          Length = 1502

 Score =  123 bits (308), Expect = 6e-29,   Method: Compositional matrix adjust.
 Identities = 68/170 (40%), Positives = 102/170 (60%), Gaps = 8/170 (4%)
 Frame = +1

Query: 11  IFKYIIIGDMGVGKSCLLHQFTEKKFMADCPHTIGVEFGTRIIEVSGQKIKLQIWDTAGQ 70
           IFK I+IGD  VGK+CL ++F   KF      TIGV+F  + I+V  + +KLQ+WDTAGQ
Sbjct: 493 IFKIIVIGDSNVGKTCLTYRFCLGKFPDKTEATIGVDFREKSIQVDSEHLKLQLWDTAGQ 672

Query: 71  ERFR-AVTRSYYRGAAGALMVYDITRRSTYNHLSSWL--TDARNLTN--PNTVIILIGNK 125
           ERFR ++ + YYR     + VYD+T+ S++ ++ +W+   D  NLT   P    IL+GNK
Sbjct: 673 ERFRKSMVQHYYRNVHAVVFVYDMTKMSSFENMPAWIEECDRHNLTKYIPR---ILVGNK 843

Query: 126 ADLEAQRDVTYEEAKQFAEENGLLFLEASAKTGE---NVEDAFLEAAKKI 172
            D+  +  V    A++FA+ + +   E SAK  E   +V+  F+  A K+
Sbjct: 844 CDVVERIAVNTNLAQKFADAHNMPLFETSAKDDEKANHVDAIFMTVAHKL 993
>14456
          Length = 1867

 Score =  111 bits (277), Expect = 2e-25,   Method: Compositional matrix adjust.
 Identities = 69/186 (37%), Positives = 104/186 (55%), Gaps = 17/186 (9%)
 Frame = -1

Query: 21   GVGKSCLLHQFTEKKFMADCPHTIGVEFGTRIIEVSGQKIKLQIWDTAGQERFRAVTRSY 80
            GVGKS L+++F   KF A   HTIGVEF  + + V  +   +QIWDTAGQERF+++   +
Sbjct: 1111 GVGKSSLMNRFVSNKFDAQSFHTIGVEFLNKDVVVDDETYTMQIWDTAGQERFKSLRTPF 932

Query: 81   YRGAAGALMVYDITRRSTYNHLSSW------LTDARN-LTNPNTVIILIGNKADLEAQRD 133
            YRGA   L+ + +    ++ +LS W        D ++ +T P    +++GNK D+E  R 
Sbjct: 931  YRGADCCLLTFSVDSMQSFRNLSMWRKEFLYYADIQDGVTFP---FVVLGNKIDVEG-RQ 764

Query: 134  VTYEEAKQFAEENG-LLFLEASAKTGENVEDAFLEAAKKIYQNIQD---------GSLDL 183
            VT EEA+ +   N    + E SAK   NVE AFL A +++ + ++D          ++DL
Sbjct: 763  VTNEEARSWCTANSNAPYFETSAKDATNVEKAFLAAVQRL-REVEDQQEVKTAHGNTVDL 587

Query: 184  NAAESG 189
            N A  G
Sbjct: 586  NRAARG 569
>17511
          Length = 483

 Score =  102 bits (254), Expect = 1e-22,   Method: Compositional matrix adjust.
 Identities = 51/122 (41%), Positives = 76/122 (62%), Gaps = 4/122 (3%)
 Frame = -3

Query: 11  IFKYIIIGDMGVGKSCLLHQFTEKKFMADCPHTIGVEFGTRIIEVSGQKIKLQIWDTAGQ 70
           + K II+GD GVGK+ L++Q+  KKF      TIG +F T+ + V  + + +QIWDTAGQ
Sbjct: 367 LLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQIWDTAGQ 188

Query: 71  ERFRAVTRSYYRGAAGALMVYDITRRSTYNHLSSW----LTDARNLTNPNTVIILIGNKA 126
           ERF+++  ++YRGA   ++V+D+T  +T+  L SW    L  A      N   ++IGNK 
Sbjct: 187 ERFQSLGVAFYRGADCCVLVFDVTMPNTFRSLDSWRDEFLIQASPRDPENFPFVVIGNKI 8

Query: 127 DL 128
           DL
Sbjct: 7   DL 2
>26083
          Length = 432

 Score = 99.4 bits (246), Expect = 9e-22,   Method: Compositional matrix adjust.
 Identities = 44/114 (38%), Positives = 74/114 (64%)
 Frame = +1

Query: 12  FKYIIIGDMGVGKSCLLHQFTEKKFMADCPHTIGVEFGTRIIEVSGQKIKLQIWDTAGQE 71
           FK + +G+  VGK+ L+ +F    F      TIG++F ++ + +  + I+LQ+WDTAGQE
Sbjct: 79  FKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTIRLQLWDTAGQE 258

Query: 72  RFRAVTRSYYRGAAGALMVYDITRRSTYNHLSSWLTDARNLTNPNTVIILIGNK 125
           RFR++  SY R ++ A++VYDIT  ++++  S W+ D R     + +I+L+GNK
Sbjct: 259 RFRSLIPSYIRDSSVAVVVYDITNANSFHQTSKWIDDVRTERGSDVIIMLVGNK 420
>05468
          Length = 1558

 Score = 98.2 bits (243), Expect = 2e-21,   Method: Compositional matrix adjust.
 Identities = 54/162 (33%), Positives = 95/162 (58%), Gaps = 7/162 (4%)
 Frame = -3

Query: 10   YIFKYIIIGDMGVGKSCLLHQFTEKKFMADCPHTIGVEFGTRIIEVSGQK-IKLQIWDTA 68
            +++K ++IG++G GK+ ++ ++  + F      TIGV+F  +++       I+LQ+WD A
Sbjct: 1544 HLYKILVIGELGTGKTSIIKRYVHQFFSQHYRATIGVDFALKVLNWDADTLIRLQLWDIA 1365

Query: 69   GQERFRAVTRSYYRGAAGALMVYDITRRSTYNHLSSWLTDARN---LTNPNTV-IILIGN 124
            GQERF  +TR YY+ A GA +V+D+TR ST++ ++ W  D  +   L + + V  +L+ N
Sbjct: 1364 GQERFGNMTRVYYKEAVGAFVVFDVTRASTFDAVTKWKNDLDSKVQLADGSPVPCVLLAN 1185

Query: 125  KADLEAQRDV-TYEEAKQFAEENGLL-FLEASAKTGENVEDA 164
            K D   +  V    +  +F  E G + + E SAK   N+++A
Sbjct: 1184 KCDQAKEGLVNNTSQMDEFCSEKGFIGWYETSAKENINIDEA 1059
>01095
          Length = 1745

 Score = 97.4 bits (241), Expect = 4e-21,   Method: Compositional matrix adjust.
 Identities = 56/127 (44%), Positives = 73/127 (57%)
 Frame = -1

Query: 89   MVYDITRRSTYNHLSSWLTDARNLTNPNTVIILIGNKADLEAQRDVTYEEAKQFAEENGL 148
            +VYDIT + T+    +W+ + +   +PN VI L GNKADL  +R V +EEA+ +AEEN L
Sbjct: 1745 VVYDITNQDTFGRAKTWVKELQRQASPNIVIALAGNKADLANKRMVEFEEAQAYAEENSL 1566

Query: 149  LFLEASAKTGENVEDAFLEAAKKIYQNIQDGSLDLNAAESGVQHKPSAPQGGRLTSEPQP 208
            LF+E SAKT  NV D FL  AKK+ +N           E G   +P   QG RL +E   
Sbjct: 1565 LFMETSAKTAMNVNDIFLAIAKKLPKN-----------EGGGGSQPR-QQGVRLNNEQSQ 1422

Query: 209  QREGCGC 215
            Q EG  C
Sbjct: 1421 QSEGGCC 1401
>07465
          Length = 1103

 Score = 96.7 bits (239), Expect = 7e-21,   Method: Compositional matrix adjust.
 Identities = 53/160 (33%), Positives = 84/160 (52%)
 Frame = +3

Query: 25  SCLLHQFTEKKFMADCPHTIGVEFGTRIIEVSGQKIKLQIWDTAGQERFRAVTRSYYRGA 84
           S ++ ++ +  F  D   TIGV+F  R IEV G+ ++L +WDTAGQE F A+T++YYRGA
Sbjct: 240 SSMIQRYCKGIFTKDYKKTIGVDFLERQIEVGGEDVRLMLWDTAGQEEFDAITKAYYRGA 419

Query: 85  AGALMVYDITRRSTYNHLSSWLTDARNLTNPNTVIILIGNKADLEAQRDVTYEEAKQFAE 144
              ++ +    R ++  L +W     +      ++I + NK DL     V  EEA+  A+
Sbjct: 420 QACVLAFSTVDRDSFEALETWKRKVEDEVGEIGMVI-VQNKIDLIDDAVVRPEEAENLAK 596

Query: 145 ENGLLFLEASAKTGENVEDAFLEAAKKIYQNIQDGSLDLN 184
           +  L F   S K   NV++ F   A K    +  G  ++N
Sbjct: 597 KLRLRFYRTSVKENMNVDEVFRYLADKYLHQLNTGMDEVN 716
>33794
          Length = 779

 Score = 95.1 bits (235), Expect = 2e-20,   Method: Compositional matrix adjust.
 Identities = 51/143 (35%), Positives = 80/143 (55%), Gaps = 4/143 (2%)
 Frame = -1

Query: 32  TEKKFMA--DCPHTI--GVEFGTRIIEVSGQKIKLQIWDTAGQERFRAVTRSYYRGAAGA 87
           TE  F +  DC   I   V + T  I + G+++KLQIWDT+GQ RF  + RSY RGA G 
Sbjct: 746 TENPFCSGNDCTSHILQTVAYKTTTILLEGKRVKLQIWDTSGQGRFCTIIRSYSRGAQGI 567

Query: 88  LMVYDITRRSTYNHLSSWLTDARNLTNPNTVIILIGNKADLEAQRDVTYEEAKQFAEENG 147
           ++VYDIT + +++ +  WL +      P    +L+GN+  L  +R V  ++A+ +A  N 
Sbjct: 566 ILVYDITNKWSFDGIDRWLKEVEEHA-PGIPKVLVGNRLHLAYKRQVAAKQAETYASRNN 390

Query: 148 LLFLEASAKTGENVEDAFLEAAK 170
           +   E S     N+ ++F E A+
Sbjct: 389 MSCFEISPLCDFNIRESFCELAR 321
>30760
          Length = 596

 Score = 92.4 bits (228), Expect = 1e-19,   Method: Compositional matrix adjust.
 Identities = 56/171 (32%), Positives = 92/171 (53%), Gaps = 9/171 (5%)
 Frame = -1

Query: 13  KYIIIGDMGVGKS--CLLHQFTEKKFMADCPHTIGVEFGTRIIEV--SGQKIKLQIWDTA 68
           K I+ GD GVGKS  C +       F  +   T GVE   +++ +  S  +++L ++D+A
Sbjct: 524 KCIVTGDSGVGKSSICQVFHSDSAHFPKNYSMTTGVEVLVKLVNIPDSRDQVELYLFDSA 345

Query: 69  GQERFRAVTRSYYRGAAGALMVYDITRRSTYNHLSSWLTDARNLTNPNTVI--ILIGNKA 126
           G+E F      ++   +  ++VYD+T  ++++    WL   R    PNTVI  +L+ NK 
Sbjct: 344 GKEIFSENVTKFWDQPSVVMVVYDVTDETSFSGCVRWLERVR-AAKPNTVIPGVLVANKT 168

Query: 127 DLEAQRDVTYEEAKQFAEENGLLFLEASAKTGENVEDAFL---EAAKKIYQ 174
           DL+ +R V+ +E K  A+ +GL + E SAK  +N +  F     A  K+YQ
Sbjct: 167 DLDERRRVSRKEGKDLAQSHGLEYFECSAKEMQNTDTPFFCLAHAFHKLYQ 15
>13901
          Length = 962

 Score = 89.7 bits (221), Expect = 9e-19,   Method: Compositional matrix adjust.
 Identities = 41/96 (42%), Positives = 63/96 (65%), Gaps = 1/96 (1%)
 Frame = -3

Query: 11  IFKYIIIGDMGVGKSCLLHQFTEKKFMADCPHTIGVEFGTRIIEVSGQ-KIKLQIWDTAG 69
           +FK IIIGD  VGK+  + ++    F  D   TIGV+F  ++I  S +  IKLQ+WD AG
Sbjct: 288 LFKVIIIGDPTVGKTSFVQRYVNDSFRRDYKMTIGVDFALKVIRWSDKCNIKLQLWDIAG 109

Query: 70  QERFRAVTRSYYRGAAGALMVYDITRRSTYNHLSSW 105
           QERF ++TR YY+ A   ++++D+T+++TY +   W
Sbjct: 108 QERFTSMTRVYYKDAHACIVMFDLTQKNTYQNAIRW 1
>33380
          Length = 282

 Score = 89.0 bits (219), Expect = 1e-18,   Method: Compositional matrix adjust.
 Identities = 35/75 (46%), Positives = 54/75 (72%)
 Frame = +3

Query: 58  QKIKLQIWDTAGQERFRAVTRSYYRGAAGALMVYDITRRSTYNHLSSWLTDARNLTNPNT 117
           +++KLQIWDTAGQER+R +T +YYRGA G +++YD+T   ++N +  W T  +  +  N 
Sbjct: 54  KRVKLQIWDTAGQERYRTITTAYYRGAMGFILMYDVTNEESFNAVQDWCTQIKTYSWDNA 233

Query: 118 VIILIGNKADLEAQR 132
            ++L+GNK DLE +R
Sbjct: 234 QVVLVGNKCDLEDER 278
>13750
          Length = 503

 Score = 85.5 bits (210), Expect = 1e-17,   Method: Compositional matrix adjust.
 Identities = 52/164 (31%), Positives = 85/164 (51%), Gaps = 3/164 (1%)
 Frame = -2

Query: 24  KSCLLHQFTEKKFMADCPHTIGV---EFGTRIIEVSGQKIKLQIWDTAGQERFRAVTRSY 80
           K+CLL ++ +  FM     TI V   EF           ++  +WDT G E +R++  S+
Sbjct: 502 KTCLLRRYQKGFFMDRTMPTIAVLCSEFNES--RTDPLNVRYTLWDTGGAETYRSLWVSH 329

Query: 81  YRGAAGALMVYDITRRSTYNHLSSWLTDARNLTNPNTVIILIGNKADLEAQRDVTYEEAK 140
           +RGA  AL+VYD+T   ++   ++    A     P   +I +G+K DLE  R ++ E  +
Sbjct: 328 FRGAQVALLVYDVTCEWSFLTATTVWRKALMKNIPEAQVIFVGSKTDLEENRVISTERGQ 149

Query: 141 QFAEENGLLFLEASAKTGENVEDAFLEAAKKIYQNIQDGSLDLN 184
            FA + G  F E S+ TG+NV+  F E A  + +  +   L+L+
Sbjct: 148 AFATQCGYTFFETSSVTGKNVDAVFWEIAFILARLQRSAHLELS 17
>01972
          Length = 2359

 Score = 83.2 bits (204), Expect = 7e-17,   Method: Compositional matrix adjust.
 Identities = 48/144 (33%), Positives = 78/144 (54%)
 Frame = +3

Query: 29  HQFTEKKFMADCPHTIGVEFGTRIIEVSGQKIKLQIWDTAGQERFRAVTRSYYRGAAGAL 88
           H+   KK++A    T+GVE    +   S  K+K  +WDTAGQE+F  +   YY     A+
Sbjct: 366 HRRI*KKYVA----TLGVEVHPLLFHTSRGKLKFNVWDTAGQEKFGGLRDGYYIQGQCAV 533

Query: 89  MVYDITRRSTYNHLSSWLTDARNLTNPNTVIILIGNKADLEAQRDVTYEEAKQFAEENGL 148
           +++D+T R TY ++ +W  D   +   N  I+L GNK D++ ++     +A  F  +  L
Sbjct: 534 IMFDVTSRVTYKNVPNWHRDLVRVCE-NIPIVLCGNKVDIKDRK--VKAKAIVFHRKKNL 704

Query: 149 LFLEASAKTGENVEDAFLEAAKKI 172
            + + SAK+  N E  FL  A+K+
Sbjct: 705 QYYDISAKSNYNFEKPFLWLARKL 776

 Score = 26.6 bits (57), Expect = 8.8,   Method: Compositional matrix adjust.
 Identities = 11/32 (34%), Positives = 19/32 (59%), Gaps = 1/32 (3%)
 Frame = +1

Query: 12  FKYIIIGDMGVGKSCLLHQFTEKKFMAD-CPH 42
           FK +++GD GVGK+  + +    +F  +  PH
Sbjct: 304 FKLVLVGDGGVGKTTFVKRHVTGEFEKNMLPH 399
>11257
          Length = 1102

 Score = 80.9 bits (198), Expect(2) = 1e-16,   Method: Compositional matrix adjust.
 Identities = 42/125 (33%), Positives = 71/125 (56%), Gaps = 5/125 (4%)
 Frame = -2

Query: 53   IEVSGQKIKLQIWDTAGQERFRAVTRSYYRGAAGALMVYDITRRSTYNHLSSWLTDARNL 112
            + V G+   +QIWDTAGQER++++   +YRG    L+ + +    +   LS W  +  N 
Sbjct: 1047 VVVDGETFTMQIWDTAGQERYKSLRTPFYRGTDCCLLTFSVDNLKSLQSLSDWYDEFVNY 868

Query: 113  TN----PNTVIILIGNKADLEAQRDVTYEEAKQFAEENG-LLFLEASAKTGENVEDAFLE 167
             +     +   ++IGNKAD+E +R+V+ E+A  +   +G L + E SAK   NV+ AFL 
Sbjct: 867  ADIQDSASFPFVIIGNKADIE-EREVSSEDAYNWCRTHGNLPYFETSAKDSLNVQQAFLA 691

Query: 168  AAKKI 172
              +++
Sbjct: 690  VVRRL 676

 Score = 22.3 bits (46), Expect(2) = 1e-16,   Method: Compositional matrix adjust.
 Identities = 10/14 (71%), Positives = 11/14 (78%), Gaps = 2/14 (14%)
 Frame = -3

Query: 40   CP--HTIGVEFGTR 51
            CP  HTIGVEF T+
Sbjct: 1091 CPVFHTIGVEFLTK 1050
>29380
          Length = 853

 Score = 81.3 bits (199), Expect = 2e-16,   Method: Compositional matrix adjust.
 Identities = 42/98 (42%), Positives = 61/98 (62%), Gaps = 1/98 (1%)
 Frame = -2

Query: 84  AAGALMVYDITRRSTYNHLSSWLTDARNLTNPNTVIILIGNKADLEAQ-RDVTYEEAKQF 142
           A+ A++VYD+    T++   +W+ + R     + +IIL GNK DL  Q R V++E+A+ F
Sbjct: 852 ASAAIIVYDVNIADTFSRALAWVKELRQQNTESVLIILAGNKVDLATQHRAVSFEDAQSF 673

Query: 143 AEENGLLFLEASAKTGENVEDAFLEAAKKIYQNIQDGS 180
           A ENGLLF E SAKTG  V + F+  A ++ Q   DGS
Sbjct: 672 ARENGLLFAEVSAKTGMAVNEIFMTLANQLIQQEIDGS 559
>07580
          Length = 921

 Score = 80.1 bits (196), Expect = 5e-16,   Method: Compositional matrix adjust.
 Identities = 44/121 (36%), Positives = 68/121 (56%), Gaps = 1/121 (0%)
 Frame = +3

Query: 53  IEVSGQKIKLQIWDTAGQERFRAVTRSYYRGAAGALMVYDITRRSTYNHLSSWLTDARNL 112
           +EV GQ+  L+I DTAG E+F A+   Y +   G L+ Y IT +ST+N L         +
Sbjct: 183 VEVDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFLLAYSITAQSTFNDLQELREQILRV 362

Query: 113 TNPNTV-IILIGNKADLEAQRDVTYEEAKQFAEENGLLFLEASAKTGENVEDAFLEAAKK 171
            + + V ++L+GNK DLE +R V  ++ +  A      FLE SAK   NV + F++  ++
Sbjct: 363 KDTDDVPMLLVGNKCDLEDERVVGKDQGQGLARSFSCAFLETSAKARINVNEIFMDLVRQ 542

Query: 172 I 172
           I
Sbjct: 543 I 545
>32723
          Length = 384

 Score = 80.1 bits (196), Expect = 7e-16,   Method: Compositional matrix adjust.
 Identities = 37/96 (38%), Positives = 55/96 (57%)
 Frame = +2

Query: 70  QERFRAVTRSYYRGAAGALMVYDITRRSTYNHLSSWLTDARNLTNPNTVIILIGNKADLE 129
           QERFR++T+SYYR A   ++VYD+  + +Y  L  W+ +         +  L+GNK D  
Sbjct: 2   QERFRSITQSYYRSANALILVYDVCSQQSYESLPQWIHEIELYAGTKVLAFLVGNKIDQT 181

Query: 130 AQRDVTYEEAKQFAEENGLLFLEASAKTGENVEDAF 165
            +R++     K+FAE   + FLE SAK  +NVE  F
Sbjct: 182 DKREIPTHIGKEFAERYEMRFLETSAKEADNVEKLF 289
>35581
          Length = 364

 Score = 79.0 bits (193), Expect = 1e-15,   Method: Compositional matrix adjust.
 Identities = 38/88 (43%), Positives = 53/88 (60%), Gaps = 2/88 (2%)
 Frame = +2

Query: 7   NYSYIFKYIIIGDMGVGKSCLLHQFTEKKFMADCPHT--IGVEFGTRIIEVSGQKIKLQI 64
           N +  FK +++GD GVGK+CLL++    KF+ D P T        T +   SG    + +
Sbjct: 32  NDTLYFKCVLLGDAGVGKTCLLNRLATDKFL-DSPLTSLTTASLLTTVTLTSGVMASVDL 208

Query: 65  WDTAGQERFRAVTRSYYRGAAGALMVYD 92
           WDTAGQER+R++T SYYR     L+VYD
Sbjct: 209 WDTAGQERYRSLTSSYYRDTKAVLIVYD 292
>26536
          Length = 829

 Score = 75.5 bits (184), Expect = 2e-14,   Method: Compositional matrix adjust.
 Identities = 43/129 (33%), Positives = 71/129 (55%), Gaps = 3/129 (2%)
 Frame = +2

Query: 40  CPHTIGVEFGTRIIEVSGQKIKLQIWDTAGQERFRAVTRSYYRGAAGALMVYDITRRSTY 99
           C  TI +   T +  +  +++     DTAGQE + ++   Y R   G ++VY +T  +++
Sbjct: 68  CERTIMLLSLTTMKMMMERRVSWTFLDTAGQEEYSSMREHYTRSGDGFIVVYSVTDVTSF 247

Query: 100 NHLSS---WLTDARNLTNPNTVIILIGNKADLEAQRDVTYEEAKQFAEENGLLFLEASAK 156
               +   WLT  ++ T+ + V  L GNK DL + R VT EE ++ A+  G+L+ E SAK
Sbjct: 248 QEAEAVFRWLTRFQDETSIHAV--LCGNKTDLTSDRKVTPEEGRKMADRLGMLYFETSAK 421

Query: 157 TGENVEDAF 165
           TG+NV   +
Sbjct: 422 TGDNVSQVY 448

 Score = 32.7 bits (73), Expect = 0.10,   Method: Compositional matrix adjust.
 Identities = 18/47 (38%), Positives = 29/47 (61%)
 Frame = +2

Query: 12  FKYIIIGDMGVGKSCLLHQFTEKKFMADCPHTIGVEFGTRIIEVSGQ 58
           +K +++G  GVGKS L  +FT+  F+     TI   +  ++I+VSGQ
Sbjct: 488 YKIVMLGSGGVGKSSLTIRFTQDTFLDVYDPTIEDSY-RKMIQVSGQ 625
>12339
          Length = 578

 Score = 70.5 bits (171), Expect = 5e-13,   Method: Compositional matrix adjust.
 Identities = 50/151 (33%), Positives = 76/151 (50%), Gaps = 5/151 (3%)
 Frame = -2

Query: 70  QERFRAVTRSYYRGAAGALMVYDITRRSTYNHLSSWLTDARNLTNPNT----VIILIGNK 125
           QERF+++  ++YRGA   ++VYD+T   T++ L SW  +  N  +P        ++IGNK
Sbjct: 577 QERFQSLGVAFYRGADCCILVYDVTEXKTFDSLDSWQREFLNQASPRDPEHFPFVVIGNK 398

Query: 126 ADLEAQRDVTYEEAKQF-AEENGLLFLEASAKTGENVEDAFLEAAKKIYQNIQDGSLDLN 184
            DL+  R VT +  + + + + G+ + E SAK   NVE AF   AK              
Sbjct: 397 IDLD-NRVVTAKRGQGWCSTKGGIPYFETSAKEAINVEQAFQTVAKNAL----------- 254

Query: 185 AAESGVQHKPSAPQGGRLTSEPQPQREGCGC 215
           A ES V+     P   RL+++    RE C C
Sbjct: 253 AQESEVEID-DFPSEIRLSNDDSRPRERCAC 164
>27191
          Length = 443

 Score = 68.6 bits (166), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 28/103 (27%), Positives = 55/103 (53%)
 Frame = +1

Query: 24  KSCLLHQFTEKKFMADCPHTIGVEFGTRIIEVSGQKIKLQIWDTAGQERFRAVTRSYYRG 83
           K+CL+  F E KF      T+GV++G +I  V+G  +++ +WD +G   +  V    Y G
Sbjct: 1   KTCLIKHFCESKFNQGYQPTVGVDYGFKIQTVNGVDMRVHMWDLSGSNEYLDVRNELYTG 180

Query: 84  AAGALMVYDITRRSTYNHLSSWLTDARNLTNPNTVIILIGNKA 126
           +    +V+D++   ++  L SWL +       + + +++GN+ 
Sbjct: 181 SDAIFIVFDVSNTPSFEALDSWLREINRFATGSPLNVIVGNRV 309
>14119
          Length = 602

 Score = 68.6 bits (166), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 37/95 (38%), Positives = 58/95 (61%), Gaps = 1/95 (1%)
 Frame = +1

Query: 98  TYNHLSSWLTDARNLTNPNTVIILIGNKADLEAQ-RDVTYEEAKQFAEENGLLFLEASAK 156
           T+N   +W+ + R     + +I+L GNKADL ++ R V+ ++A+ FAE+NGL+F E SAK
Sbjct: 1   TFNRALAWVKELRQQNAGSVLIVLAGNKADLASEHRAVSADDARTFAEDNGLIFAEVSAK 180

Query: 157 TGENVEDAFLEAAKKIYQNIQDGSLDLNAAESGVQ 191
           TG  V + F+  A K+ +  ++G        SGVQ
Sbjct: 181 TGMAVSEVFMTIAHKLVRRAEEG----GGVWSGVQ 273
>19006
          Length = 568

 Score = 67.8 bits (164), Expect = 3e-12,   Method: Compositional matrix adjust.
 Identities = 44/133 (33%), Positives = 65/133 (48%), Gaps = 1/133 (0%)
 Frame = -2

Query: 13  KYIIIGDMGVGKSCLLHQFTEKKFMADCPHTIGVEFGTRIIEVSGQKIKLQIWDTAGQER 72
           K +I+GD   GK+CLL  F++ +F      T+   +   I EV  ++++L +WDTAGQE 
Sbjct: 432 KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADI-EVDSKQVELALWDTAGQED 256

Query: 73  FRAVTRSYYRGAAGALMVYDI-TRRSTYNHLSSWLTDARNLTNPNTVIILIGNKADLEAQ 131
           +  +    Y      LM + I +  S  N    W  + R+   PN  IIL+GNK DL   
Sbjct: 255 YDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVRHFC-PNVPIILVGNKKDLRND 79

Query: 132 RDVTYEEAKQFAE 144
            +   E  K   E
Sbjct: 78  ENTKRELMKMKQE 40
>13745
          Length = 1045

 Score = 65.1 bits (157), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 39/106 (36%), Positives = 63/106 (59%), Gaps = 5/106 (4%)
 Frame = +2

Query: 70  QERFRAVTRSYYRGAAGALMVYDITRRSTYNHLSSW----LTDARNLTNPNTVIILIGNK 125
           QERF+++  ++YRGA   ++VYD+T  +++ +L SW    L  A      +   +++GNK
Sbjct: 2   QERFQSLGVAFYRGADCCVLVYDVTAPNSFKNLDSWRDEFLIQASPRDPEHFPFVVLGNK 181

Query: 126 ADLEAQRDVTYEEAKQFAE-ENGLLFLEASAKTGENVEDAFLEAAK 170
            DL+  R V+   A+Q+ + +N + + E SAK G NVE AF   AK
Sbjct: 182 VDLD-NRQVSTRRAQQWCQSKNDIPYYETSAKEGINVEMAFQTIAK 316
>11728
          Length = 635

 Score = 65.1 bits (157), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 44/160 (27%), Positives = 77/160 (48%), Gaps = 14/160 (8%)
 Frame = -1

Query: 12  FKYIIIGDMGVGKSCLLHQFTEKKFMADCPHTIGVEFGTRIIEVSGQKIKLQIWDTAGQE 71
            K +++GD  VGK+CLL  +T   F  +   T+   +   ++ V  + I L +WDTAGQE
Sbjct: 488 IKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVM-VDSKPINLGLWDTAGQE 312

Query: 72  RFRAVTRSYYRGAAGALMVYDITRRSTYNHL-SSWLTDARNLTNPNTVIILIGNKADLEA 130
            +  +    Y      L+ + +   +++ ++ + W  +  +   PNT IIL+G K DL  
Sbjct: 311 DYDRLRPLSYPQTDVFLICFSLISPASFENVKAKWYPEVSHHC-PNTPIILVGTKLDLRE 135

Query: 131 QRD------------VTYEEAKQFAEENGL-LFLEASAKT 157
            ++            +TY +    A++ G   +LE SA T
Sbjct: 134 DKETIEKLKEKKLAPITYPQGLAMAKDIGAGKYLECSALT 15
>00858
          Length = 1658

 Score = 61.6 bits (148), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 42/150 (28%), Positives = 74/150 (49%), Gaps = 1/150 (0%)
 Frame = -2

Query: 24   KSCLLHQFTEKKFMADCPHTIGVEFGTRIIEVSGQKIKLQIWDTAGQERFRAVTRSYYRG 83
            KS L  Q  +  F+ +   T       +++ + G+   L I DTAGQE   A+     R 
Sbjct: 1552 KSALTIQLXQNHFVEEYDPTXEDSXRKQVV-IDGETCLLDILDTAGQEEXSAMRDQCMRT 1376

Query: 84   AAGALMVYDITRRSTYNHLSSWLTDARNLTNPNTV-IILIGNKADLEAQRDVTYEEAKQF 142
              G L V+ +    ++  ++ +    + + + + V ++L+GNK DL   R+V   + K  
Sbjct: 1375 GEGFLCVFAVXNLKSFEDINQYREQIKRVKDADEVPMVLVGNKVDLPI-RNVEQRQGKHM 1199

Query: 143  AEENGLLFLEASAKTGENVEDAFLEAAKKI 172
            AE   + ++E SAKT + V+DAF    ++I
Sbjct: 1198 AELYHIPYVETSAKTRQGVDDAFYTLVREI 1109
>34359
          Length = 1042

 Score = 61.6 bits (148), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 33/99 (33%), Positives = 55/99 (55%)
 Frame = +3

Query: 34  KKFMADCPHTIGVEFGTRIIEVSGQKIKLQIWDTAGQERFRAVTRSYYRGAAGALMVYDI 93
           KK++A    T+GVE        S   ++  +WDTAGQE+F  +   YY     A++++D+
Sbjct: 129 KKYVA----TLGVEVHPLQFNTSRGLLRFNVWDTAGQEKFGGLRDGYYIQGTCAIIMFDV 296

Query: 94  TRRSTYNHLSSWLTDARNLTNPNTVIILIGNKADLEAQR 132
           T R TY ++ +W  D   +   N  I+L GNK D++ ++
Sbjct: 297 TSRVTYKNVPNWHRDLVRVCE-NIPIVLCGNKVDIKDRK 410
>25618
          Length = 475

 Score = 60.8 bits (146), Expect = 4e-10,   Method: Compositional matrix adjust.
 Identities = 37/101 (36%), Positives = 56/101 (55%), Gaps = 1/101 (0%)
 Frame = +3

Query: 116 NTVIILIGNKADLEAQ-RDVTYEEAKQFAEENGLLFLEASAKTGENVEDAFLEAAKKIYQ 174
           + +I+L GNKADL ++ R V+ ++A+ FAE+NGL+F E SAKTG  V + F+  A K+ +
Sbjct: 75  SVLIVLAGNKADLASEHRAVSADDARTFAEDNGLIFAEVSAKTGMAVSEVFMTIAHKLVR 254

Query: 175 NIQDGSLDLNAAESGVQHKPSAPQGGRLTSEPQPQREGCGC 215
             ++G           Q      +  RL SE +    GC C
Sbjct: 255 RAEEG-----------QGSXQGRERVRL-SEAEEASGGCKC 341
>09204
          Length = 1051

 Score = 54.7 bits (130), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 31/103 (30%), Positives = 55/103 (53%), Gaps = 4/103 (3%)
 Frame = -3

Query: 72   RFRAVTRSYYRGAAGALMVYDITRRSTYNHLSSWLTDARNLTNPNTVIILIGNKADL--- 128
            R+ A++R YYRGA  A++ +D+T +S+++ +  W+ + R        + + G K DL   
Sbjct: 1049 RYEAMSRIYYRGAKAAILCFDLTDKSSFDRIRFWIGELRQ-HEEECKLYICGTKFDLVHD 873

Query: 129  -EAQRDVTYEEAKQFAEENGLLFLEASAKTGENVEDAFLEAAK 170
               +R V    AK  A++      E S+ TG+N+E  F + A+
Sbjct: 872  DPERRAVPRSVAKALADDCMAEIYETSSMTGDNIEKLFTKIAE 744
>14775
          Length = 380

 Score = 54.7 bits (130), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 44/164 (26%), Positives = 67/164 (40%), Gaps = 3/164 (1%)
 Frame = -2

Query: 24  KSCLLHQFTEKKFMADCPHTIGV---EFGTRIIEVSGQKIKLQIWDTAGQERFRAVTRSY 80
           K+CLL ++ +  FM     TI V   EF           ++  +WDT G E +R++  S+
Sbjct: 379 KTCLLRRYQKGFFMDRTMPTIAVLCSEFNES--RTDPLNVRYTLWDTGGAETYRSLWVSH 206

Query: 81  YRGAAGALMVYDITRRSTYNHLSSWLTDARNLTNPNTVIILIGNKADLEAQRDVTYEEAK 140
           +RGA  AL+VYD                                         VT E  +
Sbjct: 205 FRGAQVALLVYD-----------------------------------------VTCERGQ 149

Query: 141 QFAEENGLLFLEASAKTGENVEDAFLEAAKKIYQNIQDGSLDLN 184
            FA + G  F E S+ TG+NV+  F E A  + +  +   L+L+
Sbjct: 148 AFATQCGYTFFETSSVTGKNVDAVFWEIAFILARLQRSAHLELS 17
>00552
          Length = 455

 Score = 53.9 bits (128), Expect = 4e-08,   Method: Compositional matrix adjust.
 Identities = 25/55 (45%), Positives = 36/55 (65%)
 Frame = -1

Query: 9   SYIFKYIIIGDMGVGKSCLLHQFTEKKFMADCPHTIGVEFGTRIIEVSGQKIKLQ 63
           S + K +++GD GVGKS L+++F   KF A   HTIGVEF T+ + V G+   +Q
Sbjct: 452 SRLLKVVLLGDGGVGKSSLMNRFVSNKFDAQSFHTIGVEFLTKDVVVDGETFTMQ 288

 Score = 42.4 bits (98), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 17/48 (35%), Positives = 27/48 (56%)
 Frame = -3

Query: 64  IWDTAGQERFRAVTRSYYRGAAGALMVYDITRRSTYNHLSSWLTDARN 111
           IWDTAGQER++++   +YRG    L+ + +    +   LS W  +  N
Sbjct: 147 IWDTAGQERYKSLRTPFYRGTDCCLLTFSVDNLKSLQSLSDWYDEFVN 4
>10708
          Length = 2775

 Score = 42.4 bits (98), Expect(2) = 6e-08,   Method: Compositional matrix adjust.
 Identities = 29/86 (33%), Positives = 39/86 (45%), Gaps = 13/86 (15%)
 Frame = -3

Query: 102  LSSWLTDARNLTNPNTVIILIGNKADLE------------AQRDVTYEEAKQFAEE-NGL 148
            L  W  + R+   PN  IIL+GNK DL              Q  V  +E +  +E+ N  
Sbjct: 2593 LKKWTPEVRHFC-PNVPIILVGNKKDLRNDENTKRELMKMKQEPVRLDEGRAMSEKINAY 2417

Query: 149  LFLEASAKTGENVEDAFLEAAKKIYQ 174
             +LE SAKT E V + F  A +   Q
Sbjct: 2416 SYLECSAKTKEGVREVFETATRAALQ 2339

 Score = 30.8 bits (68), Expect(2) = 6e-08,   Method: Compositional matrix adjust.
 Identities = 13/45 (28%), Positives = 23/45 (51%)
 Frame = -2

Query: 58   QKIKLQIWDTAGQERFRAVTRSYYRGAAGALMVYDITRRSTYNHL 102
            Q+++L +WDTAGQE +  +    Y      LM + I    +  ++
Sbjct: 2729 QQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENI 2595
>19656
          Length = 428

 Score = 50.4 bits (119), Expect = 5e-07,   Method: Compositional matrix adjust.
 Identities = 24/90 (26%), Positives = 47/90 (52%)
 Frame = +3

Query: 13  KYIIIGDMGVGKSCLLHQFTEKKFMADCPHTIGVEFGTRIIEVSGQKIKLQIWDTAGQER 72
           K +++GD  VGK+CLL  +T   F  +   T+   +   ++ V G+ + L +WDTAGQE 
Sbjct: 117 KCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVM-VDGRPVNLGLWDTAGQED 293

Query: 73  FRAVTRSYYRGAAGALMVYDITRRSTYNHL 102
           +  +    Y      L+ + +   +++ ++
Sbjct: 294 YDRLRPLSYPQTDVFLLCFSVASPASFENI 383
>34597
          Length = 773

 Score = 50.4 bits (119), Expect = 6e-07,   Method: Compositional matrix adjust.
 Identities = 28/95 (29%), Positives = 50/95 (52%)
 Frame = -2

Query: 79  SYYRGAAGALMVYDITRRSTYNHLSSWLTDARNLTNPNTVIILIGNKADLEAQRDVTYEE 138
           S+  G    LM   +  + ++ ++  WL +     N +   +++GNK D+  +R V+ E 
Sbjct: 760 SWSDGHNACLMT*RM--KKSFENIVKWLRNIDEHANEDVEKMILGNKCDMTDKRVVSKER 587

Query: 139 AKQFAEENGLLFLEASAKTGENVEDAFLEAAKKIY 173
            +  A E+ + F+E SAK+  N+E AF E A+ I 
Sbjct: 586 GEAIAREHSIRFMETSAKSNINIERAFCELAEAIL 482
>08153
          Length = 1703

 Score = 48.1 bits (113), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 32/117 (27%), Positives = 52/117 (44%), Gaps = 1/117 (0%)
 Frame = +1

Query: 13  KYIIIGDMGVGKSCLLHQFTEKKFMADCPHTIGVEFGTRIIEVSGQKIKLQIWDTAGQER 72
           + +++G    GK+ +L++    + +   P TIG    T    V  + I   +WD  GQ++
Sbjct: 88  RILMVGLDAAGKTTILYKLKLGEIVTTIP-TIGFNVET----VEYKNISFTVWDVGGQDK 252

Query: 73  FRAVTRSYYRGAAGALMVYDITRRSTYNHLSSWLTDARNLTNPNTVIILI-GNKADL 128
            R + R Y++   G + V D   R   N     L    N  +    IIL+  NK DL
Sbjct: 253 IRPLWRHYFQNTQGLIFVVDSNDRERINEAKEELARMLNEDDLRDAIILVFANKQDL 423
>31291
          Length = 446

 Score = 44.3 bits (103), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 32/123 (26%), Positives = 56/123 (45%), Gaps = 14/123 (11%)
 Frame = -1

Query: 62  LQIWDTAGQERFRAVTRSYYRGAAGALMVYDITRRSTYNHLS-SWLTDARNLTNPNTVII 120
           LQ+WDTAGQE +  +    Y      ++ + +   ++  ++   W  + R+  +P+  I+
Sbjct: 446 LQLWDTAGQEDYDRLRPLAYPNTDVFMLXFSLMSEASMKNVKVKWYPEIRH-HDPHVPIV 270

Query: 121 LIGNKADL----EAQRDVTYEEAKQFAEENG---------LLFLEASAKTGENVEDAFLE 167
           L+G K DL    EA R +        +   G           + E S+KT EN++ AF E
Sbjct: 269 LVGTKLDLRQDKEAVRKLRSSRQDPVSSNQGNDLAKAIKAKRYFECSSKTQENLKTAFEE 90

Query: 168 AAK 170
             +
Sbjct: 89  TVR 81
>09827
          Length = 1201

 Score = 43.9 bits (102), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 29/118 (24%), Positives = 52/118 (44%), Gaps = 1/118 (0%)
 Frame = -3

Query: 12   FKYIIIGDMGVGKSCLLHQFTEKKFMADCPHTIGVEFGTRIIEVSGQKIKLQIWDTAGQE 71
             + +++G    GK+ +L++    + +   P TIG    T    V  + I   +WD  GQ+
Sbjct: 1112 MRILMVGLDAAGKTTILYKLKLGEIVTTIP-TIGFNVET----VEYKNISFTVWDVGGQD 948

Query: 72   RFRAVTRSYYRGAAGALMVYDITRRSTYNHLSSWLTDARNLTN-PNTVIILIGNKADL 128
            + R + R Y++   G + V D   +         LT   N     + V+++  NK DL
Sbjct: 947  KIRPLWRHYFQNTQGLIFVVDSNDKERVQEAREELTRMLNEDELRDAVLLVFANKQDL 774
>18509
          Length = 625

 Score = 42.7 bits (99), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 28/81 (34%), Positives = 42/81 (51%), Gaps = 2/81 (2%)
 Frame = -3

Query: 101 HLSSWLTDARNLTNPNTVIILIGNKADLEAQRDVTYEEAKQFAEENGLLFLEASAKTGEN 160
           H     TD R        ++L+GNK DL   R+V   + K  AE   + ++E SAKT + 
Sbjct: 575 HQPVQRTD*RVKDADEVPMVLVGNKVDLPI-RNVEQRQGKHMAELYHIPYVETSAKTRQG 399

Query: 161 VEDAFLEAAKKI--YQNIQDG 179
           V+DAF    ++I  Y+  +DG
Sbjct: 398 VDDAFYTLVREIRKYKERKDG 336
>25796
          Length = 422

 Score = 42.4 bits (98), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 16/24 (66%), Positives = 19/24 (79%)
 Frame = -1

Query: 8  YSYIFKYIIIGDMGVGKSCLLHQF 31
          Y Y+FK++IIG  G GKSCLLH F
Sbjct: 77 YDYLFKFLIIGSAGSGKSCLLHHF 6
>10862
          Length = 2896

 Score = 42.4 bits (98), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 24/72 (33%), Positives = 32/72 (44%), Gaps = 1/72 (1%)
 Frame = -3

Query: 58   QKIKLQIWDTAGQERFRAVTRSYYRGAAGALMVYDITRRSTYNHLSSWLTDARNLTNPNT 117
            Q+ +  +WD  GQ++ R + R YY G  G + V D   R   +     L    N      
Sbjct: 2492 QECQFNVWDVGGQDKIRPLWRHYYTGTQGLIFVVDCADRDRIDEARQELHRIINDREMRD 2313

Query: 118  VIILI-GNKADL 128
             IILI  NK DL
Sbjct: 2312 AIILIFANKQDL 2277
>33605
          Length = 888

 Score = 41.6 bits (96), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 24/84 (28%), Positives = 39/84 (46%)
 Frame = +1

Query: 13  KYIIIGDMGVGKSCLLHQFTEKKFMADCPHTIGVEFGTRIIEVSGQKIKLQIWDTAGQER 72
           + +++G    GK+ +L     KKF  +   TI    G  I  +  +  KL +WD  GQ+ 
Sbjct: 502 RLLMLGLDNAGKTTIL-----KKFNGEDIDTISPTLGFNIKTLEHRGFKLNVWDVGGQQS 666

Query: 73  FRAVTRSYYRGAAGALMVYDITRR 96
            R+  R+Y+    G + V D   R
Sbjct: 667 LRSYWRNYFESTDGLVWVVDSADR 738
>32770
          Length = 387

 Score = 30.0 bits (66), Expect = 0.69,   Method: Compositional matrix adjust.
 Identities = 20/59 (33%), Positives = 29/59 (49%), Gaps = 7/59 (11%)
 Frame = +2

Query: 114 NPNTVIILIGNKADLE-----AQRD-VTYEEAKQFAEENGLL-FLEASAKTGENVEDAF 165
            P T  IL+G +ADL      A +D V   + K+ A + G L + E SA  G  ++  F
Sbjct: 20  RPGTPFILVGTQADLRHHSQPASKDMVPAHKGKKLARKVGALGYFECSALIGSGLDRVF 196
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|27370494|ref|NP_766578.1| pantothenate kinase 4 [Mus
musculus]
         (773 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

17763                                                                 144   2e-34
25204                                                                  37   0.022
>17763
          Length = 447

 Score =  144 bits (362), Expect = 2e-34,   Method: Compositional matrix adjust.
 Identities = 74/141 (52%), Positives = 96/141 (68%), Gaps = 1/141 (0%)
 Frame = -1

Query: 570 GAKAVSDVLESDPQFGFEEAKRKLQERPWLVDSYTKWLQRL-KGPPHKCALIFADNSGID 628
           GA+ +  +LE+   F F +A+ KLQ RPWL D +  W  RL +GP ++CA IF DNSG D
Sbjct: 432 GAQEIRKLLETG-TFSFLDAQDKLQTRPWLFDDFDAWTARLTQGPAYRCAAIFCDNSGAD 256

Query: 629 IILGVFTFVRELLFRGTEVILACNSGPALNDVTYSESLIVAERIAAMDPIICTALREDRL 688
           IILGVF F+R LL  GT+VIL  NS P LNDVTYSE + + +R+A + P I  AL EDRL
Sbjct: 255 IILGVFPFLRYLLSVGTQVILCANSRPTLNDVTYSELVFLVKRVADICPHITQALAEDRL 76

Query: 689 LLVQTGSSSPCLDLSRLDKGL 709
             +++G  SPCLDL  +D+ L
Sbjct: 75  AXMESGQGSPCLDLRFIDEAL 13
>25204
          Length = 924

 Score = 37.4 bits (85), Expect = 0.022,   Method: Compositional matrix adjust.
 Identities = 20/62 (32%), Positives = 34/62 (54%)
 Frame = +1

Query: 595 ERPWLVDSYTKWLQRLKGPPHKCALIFADNSGIDIILGVFTFVRELLFRGTEVILACNSG 654
           ++PW   +   W QRL    H+C +I       +I+LG F F R+L FR +E+ ++ ++ 
Sbjct: 505 KQPW---AALLWKQRLTDXAHRCKIILDPR---EILLGTFLFPRKLNFRSSEICVSADNS 666

Query: 655 PA 656
            A
Sbjct: 667 HA 672
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|82973377|ref|XP_358889.4| PREDICTED: synaptojanin 1
[Mus musculus]
         (1711 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

36691                                                                 125   2e-34
35372                                                                  95   3e-19
10169                                                                  31   4.4  
09035                                                                  30   6.4  
24502                                                                  30   7.1  
>36691
          Length = 389

 Score =  125 bits (314), Expect(2) = 2e-34,   Method: Composition-based stats.
 Identities = 57/89 (64%), Positives = 71/89 (79%), Gaps = 1/89 (1%)
 Frame = +2

Query: 522 TVRTNCLDCLDRTNSVQAFLGLEMLAKQLEALGLAEKPQLVTRFQEVFRSMWSVNGDSIS 581
           T+RTNCLDCLDRTN+VQ  +G+E+L KQLE LGLA K Q+V RF+EV+R +W  +GD IS
Sbjct: 2   TMRTNCLDCLDRTNAVQTMIGMEVLPKQLECLGLASKAQMVGRFEEVYRQIWQHSGDHIS 181

Query: 582 KIYAGTGAL-EGKAKLKDGARSVTRTIQN 609
           +IYAGTGAL  G++K +D  RS TR IQN
Sbjct: 182 RIYAGTGALGGGRSKYQDATRSATRAIQN 268

 Score = 41.2 bits (95), Expect(2) = 2e-34,   Method: Compositional matrix adjust.
 Identities = 19/32 (59%), Positives = 22/32 (68%)
 Frame = +3

Query: 605 RTIQNNFFDSSKQEAIDVLLLGNTLNSDLADK 636
           R     F DSSK EAIDVLL G++L  DLAD+
Sbjct: 252 RVPSKTFLDSSKXEAIDVLLTGSSLYGDLADR 347
>35372
          Length = 410

 Score = 94.7 bits (234), Expect = 3e-19,   Method: Compositional matrix adjust.
 Identities = 53/153 (34%), Positives = 79/153 (51%), Gaps = 8/153 (5%)
 Frame = -2

Query: 867  DYVFWCGDFNYRIDLPNEEVKELIRQQ-------NWDSLIAGDQLINQKNAGQIFRGFLE 919
            D VFWCGD N+R++     V+  + Q        +++ L+  DQL      G+IF GF E
Sbjct: 391  DCVFWCGDLNFRLERRRVAVEGKVSQMTGSDDIPHFEELLGADQLSKYVTEGKIFEGFQE 212

Query: 920  GKVTFAPTYKYDLFSEDYDTSEKCRTPAWTDRVLWRRRKWPFDRSAEDLDLLNASFQDES 979
            G++ F PT+K+D+ ++ YDTS K R P++TDRVLWR RK                   ++
Sbjct: 211  GRINFQPTFKFDINTDKYDTSSKMRIPSYTDRVLWRTRK-------------------KN 89

Query: 980  KILYTWTPGTLLHYGRA-ELKTSDHRPVVALID 1011
            ++       + LHY     +K SDHR V A  +
Sbjct: 88   QV-------SCLHYDAVMNIKVSDHRAVYAFFE 11
>10169
          Length = 350

 Score = 30.8 bits (68), Expect = 4.4,   Method: Composition-based stats.
 Identities = 22/74 (29%), Positives = 32/74 (43%), Gaps = 6/74 (8%)
 Frame = -1

Query: 932 LFSEDYDTSEKCRTPAWTDRV-LWRRRKWPFDRSAEDLDLLN-----ASFQDESKILYTW 985
           L S D D  +  R    +D V  + +  WP      +L L+N     A F+ +  I YTW
Sbjct: 254 LLSLDPD*CKCGRIHLTSDFVPFYSKTIWPIGIKLTELQLINGVNTPAKFKKDLSIYYTW 75

Query: 986 TPGTLLHYGRAELK 999
               L H+G A  +
Sbjct: 74  EKILLTHFGHAHTR 33
>09035
          Length = 1950

 Score = 30.4 bits (67), Expect = 6.4,   Method: Compositional matrix adjust.
 Identities = 23/61 (37%), Positives = 34/61 (55%), Gaps = 6/61 (9%)
 Frame = -2

Query: 357 GTRFNVR---GTNDDGH--VANFVETEQV-IYLDDCVSSFIQIRGSVPLFWEQPGLQVGS 410
           G+R  +R     +D GH  +++ V++E + I+ D  VS   Q+ G  P  W Q GL VGS
Sbjct: 695 GSRHFIRQRSAVSDTGHAPISHDVKSEFLQIFRDPAVS---QVIGHHPAAWRQTGLDVGS 525

Query: 411 H 411
           H
Sbjct: 524 H 522
>24502
          Length = 1135

 Score = 30.4 bits (67), Expect = 7.1,   Method: Composition-based stats.
 Identities = 16/53 (30%), Positives = 28/53 (52%)
 Frame = +3

Query: 1078 VEDKMWVTFLEGSSALNALSLNGKELLNRTITITLKSPDWIKHLEEEMSLEKI 1130
            VED+M +   +G          G+   +R +T T K  DW+KHL  +++L ++
Sbjct: 351  VEDRM*MDKRKG---------KGRSRTDRYVTETKKRSDWLKHLVSDLALNEV 482
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|83921618|ref|NP_033536.2| villin 2 [Mus musculus]
         (586 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

00990                                                                 143   2e-34
17332                                                                  86   5e-17
18811                                                                  57   2e-08
13951                                                                  50   3e-06
08616                                                                  32   1.0  
>00990
          Length = 3161

 Score =  143 bits (361), Expect = 2e-34,   Method: Compositional matrix adjust.
 Identities = 98/301 (32%), Positives = 153/301 (50%), Gaps = 9/301 (2%)
 Frame = +3

Query: 3   KPINVRVTTMDAE-LEFAIQPNTTGKQLFDQVVKTIGLREVWYFGLQYVD---NKGFPTW 58
           K  N  V  +D E + F +  N  G++LFD+V + + L E  YFGLQ+VD   +     W
Sbjct: 252 KGFNYEVVLLDGEHVNFELDRNAEGRELFDKVCQHLDLIEKDYFGLQFVDERISNHLKCW 431

Query: 59  LKLDKKVSAQEVRKENPVQFKFRAKFYPEDVAEELIQDITQKLFFLQVKDGILSDEIYCP 118
           L  DK++S Q  +K  P  F F  KFYP D   +L + +T+ L  LQ +  ILS ++   
Sbjct: 432 LSPDKRISKQ--KKGGPWLFDFALKFYPPD-PTQLRESLTRWLVVLQTRRDILSGKLPAT 602

Query: 119 PETAVLLGSYAVQAKFGDYNKEMHKSG-YLSSERLIPQRVMDQHKLSRDQWEDRIQVWHA 177
             T  +LGSY VQA  GDY+   H+   Y+      P + +D          ++I   H 
Sbjct: 603 YLTQAMLGSYCVQADVGDYDPNEHRGVEYIRDTPFAPNQTIDLL--------EKIVELHR 758

Query: 178 EHRGMLKDSAMLEYLKIAQDLEMYGINYFEIKNKKGTDLWLGVDALGLNIYEKDDKLTPK 237
           +H+G   D A   +L+ A+ L MYG++    ++    D+ LGV A GL +Y +  +++  
Sbjct: 759 QHKGQTPDEAETNFLENAKKLAMYGVDLHAAQDVNNVDIMLGVCASGLQVYREKLRIS-- 932

Query: 238 IGFPWSEIRNISFNDKKFVIK--PIDKKAPD--FVFYAPRLRINKRILQLCMGNHELYMR 293
             F W +I  IS+  ++F IK  P D  A +  F F     R+ KR+ ++C+ +H  +  
Sbjct: 933 -RFVWPKILKISYKRRQFYIKVRPSDNSAMENSFCFKLATHRLAKRLWKICVEHHAFFRL 1109

Query: 294 R 294
           R
Sbjct: 1110R 1112
>17332
          Length = 473

 Score = 85.9 bits (211), Expect = 5e-17,   Method: Compositional matrix adjust.
 Identities = 50/145 (34%), Positives = 80/145 (55%)
 Frame = +2

Query: 13  DAELEFAIQPNTTGKQLFDQVVKTIGLREVWYFGLQYVDNKGFPTWLKLDKKVSAQEVRK 72
           D++ +  ++ N  G  L ++V + + L E  YFGL+++D  G   WL  +K +S+Q    
Sbjct: 5   DSDHQLQVKGNWKGILLQEKVCELLNLHEKDYFGLRFIDASGQTHWLDGNKSLSSQLKGC 184

Query: 73  ENPVQFKFRAKFYPEDVAEELIQDITQKLFFLQVKDGILSDEIYCPPETAVLLGSYAVQA 132
           + P +  F  KFY  D  + L ++IT+ LFFLQVK  IL   +    + A  L +YAVQ+
Sbjct: 185 QTPHKLYFGVKFYAADPCK-LREEITRYLFFLQVKQDILQGRLPVTFDEASELCAYAVQS 361

Query: 133 KFGDYNKEMHKSGYLSSERLIPQRV 157
           + GD++   H  GY+S    IP + 
Sbjct: 362 ELGDFDPRQHTDGYVSEFCFIPNQT 436
>18811
          Length = 478

 Score = 57.0 bits (136), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 39/110 (35%), Positives = 57/110 (51%), Gaps = 5/110 (4%)
 Frame = -2

Query: 176 HAEHRGMLKDSAMLEYLKIAQDLEMYGINYFEIKNKKGTDLWLGVDALGLNIYEKDDKLT 235
           H +H+G   D A + YL+ A+ L MYG++    ++    D+ LGV + GL +Y   DKL 
Sbjct: 324 HRQHKGQTPDEAEVNYLENAKKLSMYGVDLHAAQDVNNVDIMLGVCSSGLQVYR--DKL- 154

Query: 236 PKIG-FPWSEIRNISFNDKKFVIK--PIDKKA--PDFVFYAPRLRINKRI 280
            +I  F W +I  IS+  K F +K  P D K       F  P  R+ KR+
Sbjct: 153 -RISRFVWPKIIKISYKRKHFYVKVRPADNKGLETSVSFRLPTHRLAKRL 7
>13951
          Length = 720

 Score = 49.7 bits (117), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 28/73 (38%), Positives = 40/73 (54%), Gaps = 4/73 (5%)
 Frame = -2

Query: 3   KPINVRVTTMDAE-LEFAIQPNTTGKQLFDQVVKTIGLREVWYFGLQYVD---NKGFPTW 58
           K  N  V  +D E + F +  N  G++LFD+V + + L E  YFGLQ+VD   +     W
Sbjct: 398 KGFNYEVVLLDGEHVNFELDRNAEGRELFDKVCQHLDLIEKDYFGLQFVDERISNHLKCW 219

Query: 59  LKLDKKVSAQEVR 71
           L  DK++S  E R
Sbjct: 218 LSPDKRISKTEKR 180
>08616
          Length = 2833

 Score = 31.6 bits (70), Expect = 1.0,   Method: Compositional matrix adjust.
 Identities = 23/52 (44%), Positives = 27/52 (51%), Gaps = 2/52 (3%)
 Frame = +2

Query: 171  RIQVWHAEHRGMLKDSAMLEYLKIAQDLEMYGINYFEIK--NKKGTDLWLGV 220
            RI   HA  R M    A + Y+K  Q L  +GI YF IK  N K  +L LGV
Sbjct: 1049 RIMEAHANVREMSLMEAKMAYIKAWQSLPEFGITYFRIKMANSKKEEL-LGV 1201
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|19482172|ref|NP_067532.2| retinol dehydrogenase 11
[Mus musculus]
         (316 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

26417                                                                 140   4e-34
27168                                                                  78   6e-15
03060                                                                  48   5e-06
05235                                                                  47   1e-05
07400                                                                  46   2e-05
11922                                                                  39   0.003
30783                                                                  35   0.044
03983                                                                  33   0.10 
12758                                                                  33   0.14 
18534                                                                  30   0.85 
37058                                                                  30   0.87 
05690                                                                  30   1.4  
06739                                                                  28   5.8  
00202                                                                  28   6.1  
>26417
          Length = 929

 Score =  140 bits (354), Expect(2) = 4e-34,   Method: Compositional matrix adjust.
 Identities = 74/177 (41%), Positives = 108/177 (61%), Gaps = 4/177 (2%)
 Frame = +1

Query: 115 EKHLHLLINNAGVMMCPYSKTADGFEMHIGVNXXXXXXXXXXXXXXXKESAPSRIVNLSS 174
           E  + +LINNAGV+  PY+ T DG E +   N               K SAPSRI+N+SS
Sbjct: 1   EDRVDILINNAGVIGLPYALTEDGLETNFATNHFGPFLLTNLLLDKLKSSAPSRIINVSS 180

Query: 175 LGHHLGRIHFHNLQGEKFYSAGLAYCHSKLANILFTKELAKRLKGSGVTTYSV---HPGT 231
           +    G+I   NL+ EK++     Y +SKLAN+LFT+ELA+RL  +GVT  +V   HPG+
Sbjct: 181 VVQKAGKIDLDNLKAEKYFKEHKIYFNSKLANVLFTRELARRLVATGVTDVTVHCLHPGS 360

Query: 232 VHSELTRYSS-IMRWLWQLFFVFIKTPQEGAQTSLYCALTEGLESLSGSHFSDCQLA 287
             ++L       +R+  +L  VF+ +P EGAQT+L+CA+ E ++ +SG +F+ CQLA
Sbjct: 361 XKTDLLNNMPWYVRYGMKLVRVFLLSPLEGAQTTLFCAMAEEVKDMSGKYFAQCQLA 531

 Score = 21.6 bits (44), Expect(2) = 4e-34,   Method: Compositional matrix adjust.
 Identities = 6/14 (42%), Positives = 10/14 (71%)
 Frame = +3

Query: 298 IARRLWDVSCDLLG 311
           + ++LWD+SC   G
Sbjct: 567 LCKQLWDISCQYTG 608
>27168
          Length = 665

 Score = 77.8 bits (190), Expect = 6e-15,   Method: Compositional matrix adjust.
 Identities = 56/176 (31%), Positives = 80/176 (45%), Gaps = 8/176 (4%)
 Frame = +3

Query: 20  KIRKMLSSGVCTSNVQ------LPGKVAIVTGANTGIGKETAKDLAQRGARVYLACRDVD 73
           ++R+   S  C++ +Q      L G+VA++TGAN GIG ETA+ LA  G  + LACR++ 
Sbjct: 120 QVRQRFDS--CSTALQVLHGKDLHGRVALITGANCGIGFETARSLALHGCEIILACRNLA 293

Query: 74  KGELAAREIQAVTGNSQVFVR--KLDLADTKSIRAFAKDFLAEEKHLHLLINNAGVMMCP 131
             + A   I      ++   R   LDL     ++ F +       H+  LI NAGV   P
Sbjct: 294 TAQEAIDRIAVERPAARARCRTASLDLGSLSDVKKFVEQIRQSVGHIDYLILNAGVFALP 473

Query: 132 YSKTADGFEMHIGVNXXXXXXXXXXXXXXXKESAPSRIVNLSSLGHHLGRIHFHNL 187
           Y+KT DG E    V+                    +RIV LSS  H    +   NL
Sbjct: 474 YTKTVDGLETTFQVSHLSHFYLTLQLESLFDHR--TRIVVLSSESHRFASLPVENL 635
>03060
          Length = 1893

 Score = 48.1 bits (113), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 32/100 (32%), Positives = 51/100 (51%), Gaps = 3/100 (3%)
 Frame = -1

Query: 31   TSNVQLPGKVAIVTGANTGIGKETAKDLAQRGARVYLACRDVDKGELAAREIQAVTGNSQ 90
            T    + GKV +VTGA++G+GK  AK   Q G +V LA R V++       +    G  +
Sbjct: 1710 TRAADIQGKVVLVTGASSGLGKACAKVFHQHGCQVILAGRSVERLNAVKDYLTKSEGEVK 1531

Query: 91   VF---VRKLDLADTKSIRAFAKDFLAEEKHLHLLINNAGV 127
                 V  +DL D  S++  A+  +     + ++INNAG+
Sbjct: 1530 ACEPSVLAMDLEDLNSLQQLAERAVELFGKVDVVINNAGI 1411
>05235
          Length = 944

 Score = 46.6 bits (109), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 62/239 (25%), Positives = 99/239 (41%), Gaps = 6/239 (2%)
 Frame = -2

Query: 36  LPGKVAIVTGANTGIGKETAKDLAQRGARVYLACRDVDKGELAAREIQAVTGNSQVFVRK 95
           + GK  I      GIG +T  ++ + G +  L   D  +   A  E++A+     +    
Sbjct: 877 IAGKNIIFVAGLGGIGLDTNHEIVKSGPK-NLVILDRIENPAAIAELKAINPKVTISYYP 701

Query: 96  LDLADT--KSIRAFAKDFLAEEKHLHLLINNAGVMMCPYSKTADGFEMHIGVNXXXXXXX 153
            D+  +  +S++   K   A+ K + LLIN AG++           E  I VN       
Sbjct: 700 YDVTVSVAESVKLL-KTVFAQLKKVDLLINGAGIL------DDHQIERTIAVNFTGTVNT 542

Query: 154 XXXXXX--XXKESAPSRIV-NLSSLGHHLGRIHFHNLQGEKFYSAGLAYCHSKLANILFT 210
                     ++  P  ++ N+ S+        F+++     YSA      SK   + FT
Sbjct: 541 TTAIMEFWDKRKGGPGGVIANICSV------TGFNSIYQVPVYSA------SKAXALSFT 398

Query: 211 KELAKRLKGSGVTTYSVHPGTVHSELT-RYSSIMRWLWQLFFVFIKTPQEGAQTSLYCA 268
             LAK    +GVT YS++PG  H+ L  +++S   WL     V  K      QTSL CA
Sbjct: 397 NSLAKLAHITGVTVYSINPGITHTPLVNKFNS---WLDVESHVAEKLLANPTQTSLACA 230
>07400
          Length = 1577

 Score = 46.2 bits (108), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 52/201 (25%), Positives = 77/201 (38%), Gaps = 3/201 (1%)
 Frame = -3

Query: 33   NVQLPGKVAIVTGANTGIGKETAKDLAQRGARVYLACRDVDKGELAAREIQAVTGNSQVF 92
            +V    KV ++TG +TGIG E A +  +RG  V   C DV      +   Q +     V 
Sbjct: 1455 DVPAKDKVVLITGCDTGIGHEAALEANKRGLTVVAGCLDV-----TSSGAQRLAEKKGVH 1291

Query: 93   VRKLDLADTKSIRAFAKDF--LAEEKHLHLLINNAGV-MMCPYSKTADGFEMHIGVNXXX 149
            V +LD++  +S+    K    L E K L  +INNAG   M P   T+     H+      
Sbjct: 1290 VIRLDVSSDESVANAMKSVSKLCEAKGLWAVINNAGFNRMSPVELTSMTTFHHVADVMLF 1111

Query: 150  XXXXXXXXXXXXKESAPSRIVNLSSLGHHLGRIHFHNLQGEKFYSAGLAYCHSKLANILF 209
                           A  R+V +SS             +G    +   AYC +K     F
Sbjct: 1110 GTVRVTKAVLPLVRRAKGRVVTVSS------------DRGMTTPAYSSAYCIAKFGVEAF 967

Query: 210  TKELAKRLKGSGVTTYSVHPG 230
            +      +K   V+   + PG
Sbjct: 966  SDVXRMEMKKYDVSVSIIQPG 904
>11922
          Length = 2153

 Score = 38.9 bits (89), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 31/125 (24%), Positives = 60/125 (48%), Gaps = 13/125 (10%)
 Frame = +1

Query: 35  QLPGKVAIVTGANTGIGKETAKDLAQRGARVYLACRDVD-----KGEL--AAREIQAVTG 87
           +L GK   +TGA+ GIGK  A  LA+ GA + +A +  +      G +  AA+E++   G
Sbjct: 91  KLVGKTVFITGASRGIGKAIAVKLAKDGANIVIAAKTAEAHPKLPGTIYTAAKEVEEAGG 270

Query: 88  NSQVFVRKLDLADTKSIRAFAKDFLAEEKHLHLLINNA------GVMMCPYSKTADGFEM 141
            +   +  +D+ +   ++   K    +   + +L+NNA      G +  P  +    +++
Sbjct: 271 KALPCI--VDIRNEDQVKVAVKAAADKFGGIDILVNNASAISLTGTLQTPMKR----YDL 432

Query: 142 HIGVN 146
             G+N
Sbjct: 433 MNGIN 447
>30783
          Length = 765

 Score = 35.0 bits (79), Expect = 0.044,   Method: Compositional matrix adjust.
 Identities = 19/40 (47%), Positives = 24/40 (60%)
 Frame = +1

Query: 199 YCHSKLANILFTKELAKRLKGSGVTTYSVHPGTVHSELTR 238
           YC SK A  +FT+ LA  L   GV   SV+PG+V S + R
Sbjct: 241 YCMSKAAMDMFTQCLALELAPHGVRVNSVNPGSVVSMIYR 360
>03983
          Length = 1099

 Score = 33.5 bits (75), Expect = 0.10,   Method: Compositional matrix adjust.
 Identities = 52/225 (23%), Positives = 83/225 (36%), Gaps = 16/225 (7%)
 Frame = +2

Query: 38  GKVAIVTGANTGIGKETAKDLAQRGARVYLACRDVDKGELAAREI-QAVTGNSQVFVRKL 96
           G+  ++TGA +G+GK  A      G  + L   + +  E   R++ Q V+  +      +
Sbjct: 176 GQRVLITGAGSGLGKLMAYRFMGLGCDLVLWDINTEAIEAMERDMGQQVSCKAYT----V 343

Query: 97  DLADTKSIRAFAKDFLAEEKHLHLLINNAGVMM------CPYSKTADGFEMHIGVNXXXX 150
           DL+  + I   A     E   + +L+NNAG++       CP S      E    VN    
Sbjct: 344 DLSSREQIYKAADQVKREVGGVDILVNNAGIVTGRKFLDCPDSLIEKTME----VNSNAH 511

Query: 151 XXXXXXXXXXXKESAPSRIVNLSSLGHHLGRIHFHNLQGEKFYSAGLA-YCHSKLANILF 209
                             I++++S     G               GLA YC SK A + F
Sbjct: 512 FWTVKAFLPNMLAQNKGHIISIASSAGLFG-------------VTGLADYCASKFAAVGF 652

Query: 210 TKELAKRLKGSG--------VTTYSVHPGTVHSELTRYSSIMRWL 246
            + L   L+  G        V  Y ++ G      TR+  I+  L
Sbjct: 653 DESLRFELEAMGKTGVHTTVVCPYFINTGMFDGVKTRFPLILPIL 787
>12758
          Length = 804

 Score = 33.1 bits (74), Expect = 0.14,   Method: Compositional matrix adjust.
 Identities = 18/57 (31%), Positives = 30/57 (52%)
 Frame = -1

Query: 182 IHFHNLQGEKFYSAGLAYCHSKLANILFTKELAKRLKGSGVTTYSVHPGTVHSELTR 238
           ++  ++ G + +   LAYC +K A   FT+ +A  L    V    V+PG + SEL +
Sbjct: 495 VNVSSVNGMRSFPNVLAYCMAKSAIDQFTRCVALELAPKKVRVNGVNPGVIISELQK 325
>18534
          Length = 406

 Score = 30.4 bits (67), Expect = 0.85,   Method: Compositional matrix adjust.
 Identities = 14/43 (32%), Positives = 26/43 (60%), Gaps = 1/43 (2%)
 Frame = -2

Query: 96  LDLADTKSIRAFAKDFLAEEKHLHLLINNAGVMMC-PYSKTAD 137
           +D++D + I   A   + +  H+ +LINNAG++ C P+ +  D
Sbjct: 387 VDISDREQIYQRAAQVIDDVGHVDVLINNAGIVCCKPFWELHD 259
>37058
          Length = 284

 Score = 30.4 bits (67), Expect = 0.87,   Method: Composition-based stats.
 Identities = 16/33 (48%), Positives = 19/33 (57%)
 Frame = -1

Query: 270 TEGLESLSGSHFSDCQLAWVSYQGRNEIIARRL 302
           T G   L G+ F D Q   VS+QG +E  ARRL
Sbjct: 281 TPGFIQLEGNQFKDFQDQLVSFQGCSEQKARRL 183
>05690
          Length = 1192

 Score = 30.0 bits (66), Expect = 1.4,   Method: Compositional matrix adjust.
 Identities = 45/209 (21%), Positives = 85/209 (40%), Gaps = 5/209 (2%)
 Frame = +2

Query: 38  GKVAIVTGANTGIGKETAKDLAQRGARVYLACRDVDKGELAAREIQAVTGNSQVFVRKLD 97
           GK   +TG + G+G   A  L + G +V+  C  +  G    + ++A   + ++    LD
Sbjct: 173 GKAVFITGCDAGLGHLLAIHLDKLGVKVFAGC--LFPGGEGEQTLKA-KCSQRLCTVPLD 343

Query: 98  LADTKSIRAFAKDFLAEE---KHLHLLINNAGVMM--CPYSKTADGFEMHIGVNXXXXXX 152
           +   + I   A D +  E   + L  ++NNAG+M   C         +  + VN      
Sbjct: 344 VCSLE-IVTTAADTVKRELDGQELWGVVNNAGIMHIGCLEVMGQADVDKILDVNYRGQVN 520

Query: 153 XXXXXXXXXKESAPSRIVNLSSLGHHLGRIHFHNLQGEKFYSAGLAYCHSKLANILFTKE 212
                    + S   R+VN++S    +  + +H +           YC SK A    T+ 
Sbjct: 521 VIRAFLPFLRRSR-GRLVNVAS-NTGIAPVPYHAV-----------YCASKAAVAALTES 661

Query: 213 LAKRLKGSGVTTYSVHPGTVHSELTRYSS 241
           L   L+  GV   ++ P    + + ++++
Sbjct: 662 LRLELQPFGVRVSTIIPSGYRTGIQQHNT 748
>06739
          Length = 2094

 Score = 27.7 bits (60), Expect = 5.8,   Method: Compositional matrix adjust.
 Identities = 17/50 (34%), Positives = 25/50 (50%), Gaps = 3/50 (6%)
 Frame = +3

Query: 173 SSLGHHLGRIHFHNLQGEKFYS---AGLAYCHSKLANILFTKELAKRLKG 219
           S L  H    HFHN+  +K++      L  CHS++A  +F + L   L G
Sbjct: 306 SILIRHQNSAHFHNIPMKKYFKIVCVILKQCHSQMA*SMFPRHLILVLLG 455
>00202
          Length = 1009

 Score = 27.7 bits (60), Expect = 6.1,   Method: Compositional matrix adjust.
 Identities = 17/55 (30%), Positives = 27/55 (49%)
 Frame = +3

Query: 254 IKTPQEGAQTSLYCALTEGLESLSGSHFSDCQLAWVSYQGRNEIIARRLWDVSCD 308
           +K      +  L  A+ +  ES SGS     ++  VS    +EI+ARR+  V C+
Sbjct: 285 LKVENFDCKCKLKSAVAKAKESCSGSSHKVNKIGCVSQFSDDEILARRMNVVDCN 449
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|94364680|ref|XP_985636.1| PREDICTED: similar to Rab3
GTPase-activating protein non-catalytic subunit (Rab3
GTPase-activating protein 150 kDa subunit) (Rab3-GAP p150) (Rab3-GAP
regulatory subunit) (RAB3-GAP150) isoform 4 [Mus musculus]
         (1387 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

32097                                                                 128   4e-34
20290                                                                  33   0.92 
02114                                                                  32   2.5  
36903                                                                  31   4.5  
>32097
          Length = 441

 Score =  128 bits (321), Expect(2) = 4e-34,   Method: Composition-based stats.
 Identities = 65/118 (55%), Positives = 89/118 (75%), Gaps = 1/118 (0%)
 Frame = +3

Query: 95  KAAFLVPKWKHGDKGKE-EMQFAVGWSGSVSAEEGEYVTSALCIPLASQKRSSTGRPDWT 153
           K   L  KW   +KG+E + + +  W G+V+ E+GE +T  +C+PLASQKRS+ G PDWT
Sbjct: 3   KVCVLTQKWDPQNKGEEMDTRLSSVWEGTVTQEDGELITDVICLPLASQKRSTQGAPDWT 182

Query: 154 CIVVGFTSGYVRFYTESGVLLLAQLLNEDKVLQLKCRTYEIPRHPGVTEQNEELSILY 211
           C+VVGF++GYVR YTE+GVLLL+QLL+ + V +LKCRTYE PR  G+ E++EEL I+Y
Sbjct: 183 CVVVGFSTGYVRMYTETGVLLLSQLLHLEPVQRLKCRTYEPPRFMGMAEKHEELIIVY 356

 Score = 36.6 bits (83), Expect(2) = 4e-34,   Method: Composition-based stats.
 Identities = 15/20 (75%), Positives = 18/20 (90%)
 Frame = +2

Query: 214 AIVTIDGFSLFQSLRACRNQ 233
           A+V+IDGFSL QSLRACR +
Sbjct: 362 AVVSIDGFSLIQSLRACRTR 421
>20290
          Length = 1550

 Score = 32.7 bits (73), Expect = 0.92,   Method: Compositional matrix adjust.
 Identities = 12/50 (24%), Positives = 27/50 (54%), Gaps = 7/50 (14%)
 Frame = +3

Query: 1009 DVLHAHCCWEYVVQWNKDPEEARFLVRSIE-------HLKHILNPHVQNG 1051
            D LH+H CW +  +W      A ++V++ +       H++H+L+  +++ 
Sbjct: 819  DHLHSHACW*FAARWRSRASNAEYIVQTAKISPKFQNHVRHLLHDKIRDA 968
>02114
          Length = 1072

 Score = 31.6 bits (70), Expect = 2.5,   Method: Compositional matrix adjust.
 Identities = 18/74 (24%), Positives = 33/74 (44%), Gaps = 1/74 (1%)
 Frame = +2

Query: 297 PPAMSQYITVGSSPFTGFFYALEGSTQ-PLLSHVALAVASKLTSALFSAASGWLGWKSKH 355
           PP    +IT GS      ++  E ST   + +   L++  +      ++ SGW  W+   
Sbjct: 737 PPTTESWIT*GS------WWRTEWSTSTSVTTRATLSLTERRVKVT*TSCSGWWRWERTW 898

Query: 356 EEDTVQKQKPKMEP 369
              TV +++P+  P
Sbjct: 899 RSATVXERRPETSP 940
>36903
          Length = 455

 Score = 30.8 bits (68), Expect = 4.5,   Method: Composition-based stats.
 Identities = 16/41 (39%), Positives = 20/41 (48%)
 Frame = +3

Query: 957 CANKERDVENPDEPREGITRSFPEVSEVEIDLGAVPDLLHL 997
           CA       N D+PR GIT  F E S    +  + PD+L L
Sbjct: 39  CALHRDKFSNTDKPRSGITAFFSESSMSGANCASWPDILFL 161
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6755258|ref|NP_035355.1| RAB18, member RAS oncogene
family [Mus musculus]
         (206 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

08428                                                                 140   5e-34
33374                                                                 106   1e-29
34468                                                                 122   1e-28
26083                                                                 109   8e-25
17511                                                                 107   3e-24
14456                                                                 105   2e-23
05468                                                                  95   2e-20
33794                                                                  90   6e-19
07465                                                                  90   7e-19
32723                                                                  88   3e-18
01398                                                                  87   3e-18
13901                                                                  87   6e-18
33380                                                                  83   7e-17
01972                                                                  81   3e-16
11257                                                                  80   5e-16
30760                                                                  79   1e-15
19006                                                                  76   8e-15
07580                                                                  75   2e-14
35581                                                                  72   2e-13
01095                                                                  71   3e-13
00858                                                                  70   6e-13
12339                                                                  67   4e-12
27191                                                                  67   7e-12
13745                                                                  66   1e-11
11728                                                                  65   1e-11
26536                                                                  64   4e-11
34359                                                                  64   5e-11
13750                                                                  62   2e-10
19656                                                                  62   2e-10
29380                                                                  60   8e-10
34597                                                                  51   1e-08
00552                                                                  50   9e-07
09827                                                                  48   3e-06
08153                                                                  47   5e-06
33605                                                                  46   1e-05
14775                                                                  46   1e-05
10862                                                                  45   2e-05
31291                                                                  44   4e-05
18509                                                                  44   5e-05
09204                                                                  44   6e-05
31928                                                                  36   0.011
10708                                                                  35   0.022
31932                                                                  33   0.11 
30917                                                                  29   1.5  
34156                                                                  28   1.8  
>08428
          Length = 1109

 Score =  140 bits (352), Expect = 5e-34,   Method: Compositional matrix adjust.
 Identities = 71/162 (43%), Positives = 101/162 (62%), Gaps = 1/162 (0%)
 Frame = -3

Query: 9    LKILIIGESGVGKSSLLLRFTDDTFDPELAATIGVDFKVKTISVDGNKAKLAIWDTAGQE 68
            +K+ ++G+SGVGKSS++LRF   ++ P   +TIG  F  K++ VDG   +  IWDTAGQE
Sbjct: 1068 VKVCLLGDSGVGKSSIVLRFVTGSYRPSQESTIGASFMSKSLVVDGAGYRFQIWDTAGQE 889

Query: 69   RFRTLTPSYYRGAQGVILVYDVTRRDTFVKLDNWLNELETYCTRNDIVNMLVGNKID-KE 127
            +FR L P YYRGA   ++VYDVTR  TF  + +W+ EL ++   N IV  + GNK D +E
Sbjct: 888  KFRALAPMYYRGAAAAVIVYDVTRPRTFKSVKSWIQELRSFGPPN-IVLAIAGNKCDLEE 712

Query: 128  NREVDRNEGLKFARKHSMLFIEASAKTCDGVQCAFEELVEKI 169
             REV   +  ++A   S +F E SA T   V+  F EL  ++
Sbjct: 711  LREVVEKDAQEYASSISAIFGETSAMTAVNVEEMFTELARQL 586
>33374
          Length = 489

 Score =  106 bits (265), Expect(2) = 1e-29,   Method: Compositional matrix adjust.
 Identities = 54/115 (46%), Positives = 72/115 (62%), Gaps = 1/115 (0%)
 Frame = +1

Query: 45  FKVKTISVDGNKAKLAIWDTAGQERFRTLTPSYYRGAQGVILVYDVTRRDTFVKLDNWLN 104
           F  +T+ +D    K  IWDTAGQER+ +L P YYRGAQ  I+VYD+T +DTF +   W+ 
Sbjct: 139 FLTQTVCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNQDTFGRAKTWVK 318

Query: 105 ELETYCTRNDIVNMLVGNKIDKEN-REVDRNEGLKFARKHSMLFIEASAKTCDGV 158
           EL+   + N IV  L GNK D  N R V+  E   +A ++S+LF+E SAKT   V
Sbjct: 319 ELQRQASPN-IVIALAGNKADLANKRMVEFEEAQAYAEENSLLFMETSAKTAMNV 480

 Score = 39.7 bits (91), Expect(2) = 1e-29,   Method: Compositional matrix adjust.
 Identities = 18/40 (45%), Positives = 25/40 (62%)
 Frame = +2

Query: 6  LTTLKILIIGESGVGKSSLLLRFTDDTFDPELAATIGVDF 45
          +   K++++GES VGKSSL+LRF    F     +TIG  F
Sbjct: 23 ICQFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAF 142
>34468
          Length = 1502

 Score =  122 bits (305), Expect = 1e-28,   Method: Compositional matrix adjust.
 Identities = 65/147 (44%), Positives = 86/147 (58%), Gaps = 2/147 (1%)
 Frame = +1

Query: 9   LKILIIGESGVGKSSLLLRFTDDTFDPELAATIGVDFKVKTISVDGNKAKLAIWDTAGQE 68
            KI++IG+S VGK+ L  RF    F  +  ATIGVDF+ K+I VD    KL +WDTAGQE
Sbjct: 496 FKIIVIGDSNVGKTCLTYRFCLGKFPDKTEATIGVDFREKSIQVDSEHLKLQLWDTAGQE 675

Query: 69  RFR-TLTPSYYRGAQGVILVYDVTRRDTFVKLDNWLNELETYCTRNDIVNMLVGNKIDKE 127
           RFR ++   YYR    V+ VYD+T+  +F  +  W+ E + +     I  +LVGNK D  
Sbjct: 676 RFRKSMVQHYYRNVHAVVFVYDMTKMSSFENMPAWIEECDRHNLTKYIPRILVGNKCDVV 855

Query: 128 NR-EVDRNEGLKFARKHSMLFIEASAK 153
            R  V+ N   KFA  H+M   E SAK
Sbjct: 856 ERIAVNTNLAQKFADAHNMPLFETSAK 936
>26083
          Length = 432

 Score =  109 bits (272), Expect = 8e-25,   Method: Compositional matrix adjust.
 Identities = 52/118 (44%), Positives = 79/118 (66%)
 Frame = +1

Query: 6   LTTLKILIIGESGVGKSSLLLRFTDDTFDPELAATIGVDFKVKTISVDGNKAKLAIWDTA 65
           L   K++ +GE  VGK+SL+ RF  D+FD    ATIG+DF  KT+ ++    +L +WDTA
Sbjct: 70  LRKFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTIRLQLWDTA 249

Query: 66  GQERFRTLTPSYYRGAQGVILVYDVTRRDTFVKLDNWLNELETYCTRNDIVNMLVGNK 123
           GQERFR+L PSY R +   ++VYD+T  ++F +   W++++ T    +D++ MLVGNK
Sbjct: 250 GQERFRSLIPSYIRDSSVAVVVYDITNANSFHQTSKWIDDVRTE-RGSDVIIMLVGNK 420
>17511
          Length = 483

 Score =  107 bits (268), Expect = 3e-24,   Method: Compositional matrix adjust.
 Identities = 54/120 (45%), Positives = 79/120 (65%), Gaps = 3/120 (2%)
 Frame = -3

Query: 9   LKILIIGESGVGKSSLLLRFTDDTFDPELAATIGVDFKVKTISVDGNKAKLAIWDTAGQE 68
           LK++I+G+SGVGK+SL+ ++ +  F  +  ATIG DF  K + VD     + IWDTAGQE
Sbjct: 364 LKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQIWDTAGQE 185

Query: 69  RFRTLTPSYYRGAQGVILVYDVTRRDTFVKLDNWLNELETYCTRNDIVN---MLVGNKID 125
           RF++L  ++YRGA   +LV+DVT  +TF  LD+W +E     +  D  N   +++GNKID
Sbjct: 184 RFQSLGVAFYRGADCCVLVFDVTMPNTFRSLDSWRDEFLIQASPRDPENFPFVVIGNKID 5
>14456
          Length = 1867

 Score =  105 bits (261), Expect = 2e-23,   Method: Compositional matrix adjust.
 Identities = 71/188 (37%), Positives = 99/188 (52%), Gaps = 7/188 (3%)
 Frame = -1

Query: 9    LKILI---IGESGVGKSSLLLRFTDDTFDPELAATIGVDFKVKTISVDGNKAKLAIWDTA 65
            LKI +   + + GVGKSSL+ RF  + FD +   TIGV+F  K + VD     + IWDTA
Sbjct: 1147 LKITLDKQLKQGGVGKSSLMNRFVSNKFDAQSFHTIGVEFLNKDVVVDDETYTMQIWDTA 968

Query: 66   GQERFRTLTPSYYRGAQGVILVYDVTRRDTFVKLDNWLNELETYCTRNDIVN---MLVGN 122
            GQERF++L   +YRGA   +L + V    +F  L  W  E   Y    D V    +++GN
Sbjct: 967  GQERFKSLRTPFYRGADCCLLTFSVDSMQSFRNLSMWRKEFLYYADIQDGVTFPFVVLGN 788

Query: 123  KIDKENREVDRNEGLKFARKHS-MLFIEASAKTCDGVQCAFEELVEKIIQTPGLWESENQ 181
            KID E R+V   E   +   +S   + E SAK    V+ AF   V++      L E E+Q
Sbjct: 787  KIDVEGRQVTNEEARSWCTANSNAPYFETSAKDATNVEKAFLAAVQR------LREVEDQ 626

Query: 182  NKGVKLSH 189
             + VK +H
Sbjct: 625  QE-VKTAH 605
>05468
          Length = 1558

 Score = 95.1 bits (235), Expect = 2e-20,   Method: Compositional matrix adjust.
 Identities = 60/169 (35%), Positives = 92/169 (54%), Gaps = 7/169 (4%)
 Frame = -3

Query: 10   KILIIGESGVGKSSLLLRFTDDTFDPELAATIGVDFKVKTISVDGNK-AKLAIWDTAGQE 68
            KIL+IGE G GK+S++ R+    F     ATIGVDF +K ++ D +   +L +WD AGQE
Sbjct: 1535 KILVIGELGTGKTSIIKRYVHQFFSQHYRATIGVDFALKVLNWDADTLIRLQLWDIAGQE 1356

Query: 69   RFRTLTPSYYRGAQGVILVYDVTRRDTFVKLDNWLNELETYCTRND---IVNMLVGNKID 125
            RF  +T  YY+ A G  +V+DVTR  TF  +  W N+L++     D   +  +L+ NK D
Sbjct: 1355 RFGNMTRVYYKEAVGAFVVFDVTRASTFDAVTKWKNDLDSKVQLADGSPVPCVLLANKCD 1176

Query: 126  KENREVDRNEGL--KFARKHSML-FIEASAKTCDGVQCAFEELVEKIIQ 171
            +    +  N     +F  +   + + E SAK    +  A   LV +I++
Sbjct: 1175 QAKEGLVNNTSQMDEFCSEKGFIGWYETSAKENINIDEAARFLVTRILE 1029
>33794
          Length = 779

 Score = 90.1 bits (222), Expect = 6e-19,   Method: Compositional matrix adjust.
 Identities = 55/147 (37%), Positives = 83/147 (56%), Gaps = 2/147 (1%)
 Frame = -1

Query: 43  VDFKVKTISVDGNKAKLAIWDTAGQERFRTLTPSYYRGAQGVILVYDVTRRDTFVKLDNW 102
           V +K  TI ++G + KL IWDT+GQ RF T+  SY RGAQG+ILVYD+T + +F  +D W
Sbjct: 692 VAYKTTTILLEGKRVKLQIWDTSGQGRFCTIIRSYSRGAQGIILVYDITNKWSFDGIDRW 513

Query: 103 LNELETYCTRNDIVNMLVGNKID-KENREVDRNEGLKFARKHSMLFIEASAKTCD-GVQC 160
           L E+E +     I  +LVGN++     R+V   +   +A +++M   E S   CD  ++ 
Sbjct: 512 LKEVEEHAP--GIPKVLVGNRLHLAYKRQVAAKQAETYASRNNMSCFEISP-LCDFNIRE 342

Query: 161 AFEELVEKIIQTPGLWESENQNKGVKL 187
           +F EL    +   G+      NK + L
Sbjct: 341 SFCELARMALHRNGMEHIWRSNKVLSL 261
>07465
          Length = 1103

 Score = 89.7 bits (221), Expect = 7e-19,   Method: Compositional matrix adjust.
 Identities = 54/151 (35%), Positives = 77/151 (50%), Gaps = 1/151 (0%)
 Frame = +3

Query: 22  SSLLLRFTDDTFDPELAATIGVDFKVKTISVDGNKAKLAIWDTAGQERFRTLTPSYYRGA 81
           SS++ R+    F  +   TIGVDF  + I V G   +L +WDTAGQE F  +T +YYRGA
Sbjct: 240 SSMIQRYCKGIFTKDYKKTIGVDFLERQIEVGGEDVRLMLWDTAGQEEFDAITKAYYRGA 419

Query: 82  QGVILVYDVTRRDTFVKLDNWLNELETYCTRNDIVNMLVGNKIDKENREVDR-NEGLKFA 140
           Q  +L +    RD+F  L+ W  ++E      +I  ++V NKID  +  V R  E    A
Sbjct: 420 QACVLAFSTVDRDSFEALETWKRKVEDEV--GEIGMVIVQNKIDLIDDAVVRPEEAENLA 593

Query: 141 RKHSMLFIEASAKTCDGVQCAFEELVEKIIQ 171
           +K  + F   S K    V   F  L +K + 
Sbjct: 594 KKLRLRFYRTSVKENMNVDEVFRYLADKYLH 686
>32723
          Length = 384

 Score = 87.8 bits (216), Expect = 3e-18,   Method: Compositional matrix adjust.
 Identities = 43/104 (41%), Positives = 66/104 (63%), Gaps = 1/104 (0%)
 Frame = +2

Query: 67  QERFRTLTPSYYRGAQGVILVYDVTRRDTFVKLDNWLNELETYCTRNDIVNMLVGNKIDK 126
           QERFR++T SYYR A  +ILVYDV  + ++  L  W++E+E Y     ++  LVGNKID+
Sbjct: 2   QERFRSITQSYYRSANALILVYDVCSQQSYESLPQWIHEIELYAG-TKVLAFLVGNKIDQ 178

Query: 127 -ENREVDRNEGLKFARKHSMLFIEASAKTCDGVQCAFEELVEKI 169
            + RE+  + G +FA ++ M F+E SAK  D V+  F  +  ++
Sbjct: 179 TDKREIPTHIGKEFAERYEMRFLETSAKEADNVEKLFSTIAYQL 310
>01398
          Length = 1421

 Score = 87.4 bits (215), Expect = 3e-18,   Method: Compositional matrix adjust.
 Identities = 41/106 (38%), Positives = 65/106 (61%), Gaps = 1/106 (0%)
 Frame = -2

Query: 67   QERFRTLTPSYYRGAQGVILVYDVTRRDTFVKLDNWLNELETYCTRNDIVNMLVGNKIDK 126
            QERFR++T SYYR + GVI+VYD+T+R TF  L  W  E   +   +  + +++G+K D+
Sbjct: 1420 QERFRSITRSYYRNSVGVIIVYDITKRSTFENLKQWYEEARNHIEPHKAIFLVLGHKSDR 1241

Query: 127  EN-REVDRNEGLKFARKHSMLFIEASAKTCDGVQCAFEELVEKIIQ 171
            E+ R+V   EG +FA  H + F E SAK+   ++  F ++ +   Q
Sbjct: 1240 EDARQVTAREGRRFAEMHGLKFFETSAKSGHNIEDVFAQIAKDTYQ 1103
>13901
          Length = 962

 Score = 86.7 bits (213), Expect = 6e-18,   Method: Compositional matrix adjust.
 Identities = 43/103 (41%), Positives = 66/103 (64%), Gaps = 1/103 (0%)
 Frame = -3

Query: 1   MDEDVLTTLKILIIGESGVGKSSLLLRFTDDTFDPELAATIGVDFKVKTIS-VDGNKAKL 59
           M E+VL   K++IIG+  VGK+S + R+ +D+F  +   TIGVDF +K I   D    KL
Sbjct: 303 MSEEVL--FKVIIIGDPTVGKTSFVQRYVNDSFRRDYKMTIGVDFALKVIRWSDKCNIKL 130

Query: 60  AIWDTAGQERFRTLTPSYYRGAQGVILVYDVTRRDTFVKLDNW 102
            +WD AGQERF ++T  YY+ A   I+++D+T+++T+     W
Sbjct: 129 QLWDIAGQERFTSMTRVYYKDAHACIVMFDLTQKNTYQNAIRW 1
>33380
          Length = 282

 Score = 82.8 bits (203), Expect(2) = 7e-17,   Method: Compositional matrix adjust.
 Identities = 41/83 (49%), Positives = 56/83 (67%)
 Frame = +3

Query: 49  TISVDGNKAKLAIWDTAGQERFRTLTPSYYRGAQGVILVYDVTRRDTFVKLDNWLNELET 108
           T+     + KL IWDTAGQER+RT+T +YYRGA G IL+YDVT  ++F  + +W  +++T
Sbjct: 36  TVFRQDKRVKLQIWDTAGQERYRTITTAYYRGAMGFILMYDVTNEESFNAVQDWCTQIKT 215

Query: 109 YCTRNDIVNMLVGNKIDKENREV 131
           Y   N  V +LVGNK D E+  V
Sbjct: 216 YSWDNAQV-VLVGNKCDLEDERV 281

 Score = 20.8 bits (42), Expect(2) = 7e-17,   Method: Compositional matrix adjust.
 Identities = 6/14 (42%), Positives = 11/14 (78%)
 Frame = +2

Query: 37 LAATIGVDFKVKTI 50
            +T+G+DFKV ++
Sbjct: 2  FVSTVGIDFKVNSL 43
>01972
          Length = 2359

 Score = 80.9 bits (198), Expect = 3e-16,   Method: Compositional matrix adjust.
 Identities = 47/140 (33%), Positives = 74/140 (52%)
 Frame = +3

Query: 36  ELAATIGVDFKVKTISVDGNKAKLAIWDTAGQERFRTLTPSYYRGAQGVILVYDVTRRDT 95
           +  AT+GV+           K K  +WDTAGQE+F  L   YY   Q  ++++DVT R T
Sbjct: 384 KYVATLGVEVHPLLFHTSRGKLKFNVWDTAGQEKFGGLRDGYYIQGQCAVIMFDVTSRVT 563

Query: 96  FVKLDNWLNELETYCTRNDIVNMLVGNKIDKENREVDRNEGLKFARKHSMLFIEASAKTC 155
           +  + NW  +L   C    IV  L GNK+D ++R+V + + + F RK ++ + + SAK+ 
Sbjct: 564 YKNVPNWHRDLVRVCENIPIV--LCGNKVDIKDRKV-KAKAIVFHRKKNLQYYDISAKSN 734

Query: 156 DGVQCAFEELVEKIIQTPGL 175
              +  F  L  K++  P L
Sbjct: 735 YNFEKPFLWLARKLVGDPNL 794
>11257
          Length = 1102

 Score = 80.1 bits (196), Expect = 5e-16,   Method: Compositional matrix adjust.
 Identities = 44/126 (34%), Positives = 65/126 (51%), Gaps = 4/126 (3%)
 Frame = -2

Query: 48   KTISVDGNKAKLAIWDTAGQERFRTLTPSYYRGAQGVILVYDVTRRDTFVKLDNWLNELE 107
            K + VDG    + IWDTAGQER+++L   +YRG    +L + V    +   L +W +E  
Sbjct: 1053 KDVVVDGETFTMQIWDTAGQERYKSLRTPFYRGTDCCLLTFSVDNLKSLQSLSDWYDEFV 874

Query: 108  TYCTRNDIVN---MLVGNKIDKENREVDRNEGLKFARKHSML-FIEASAKTCDGVQCAFE 163
             Y    D  +   +++GNK D E REV   +   + R H  L + E SAK    VQ AF 
Sbjct: 873  NYADIQDSASFPFVIIGNKADIEEREVSSEDAYNWCRTHGNLPYFETSAKDSLNVQQAFL 694

Query: 164  ELVEKI 169
             +V ++
Sbjct: 693  AVVRRL 676
>30760
          Length = 596

 Score = 79.0 bits (193), Expect = 1e-15,   Method: Compositional matrix adjust.
 Identities = 51/158 (32%), Positives = 78/158 (49%), Gaps = 5/158 (3%)
 Frame = -1

Query: 10  KILIIGESGVGKSSLLLRFTDDT--FDPELAATIGVDFKVKTISVDGNK--AKLAIWDTA 65
           K ++ G+SGVGKSS+   F  D+  F    + T GV+  VK +++  ++   +L ++D+A
Sbjct: 524 KCIVTGDSGVGKSSICQVFHSDSAHFPKNYSMTTGVEVLVKLVNIPDSRDQVELYLFDSA 345

Query: 66  GQERFRTLTPSYYRGAQGVILVYDVTRRDTFVKLDNWLNELETYCTRNDIVNMLVGNKID 125
           G+E F      ++     V++VYDVT   +F     WL  +        I  +LV NK D
Sbjct: 344 GKEIFSENVTKFWDQPSVVMVVYDVTDETSFSGCVRWLERVRAAKPNTVIPGVLVANKTD 165

Query: 126 -KENREVDRNEGLKFARKHSMLFIEASAKTCDGVQCAF 162
             E R V R EG   A+ H + + E SAK        F
Sbjct: 164 LDERRRVSRKEGKDLAQSHGLEYFECSAKEMQNTDTPF 51
>19006
          Length = 568

 Score = 76.3 bits (186), Expect = 8e-15,   Method: Compositional matrix adjust.
 Identities = 44/138 (31%), Positives = 72/138 (52%), Gaps = 1/138 (0%)
 Frame = -2

Query: 10  KILIIGESGVGKSSLLLRFTDDTFDPELAATIGVDFKVKTISVDGNKAKLAIWDTAGQER 69
           K++I+G+   GK+ LL+ F+ D F PE+      +  V  I VD  + +LA+WDTAGQE 
Sbjct: 432 KLVIVGDGACGKTCLLIVFSKDQF-PEVYVPTVFENYVADIEVDSKQVELALWDTAGQED 256

Query: 70  FRTLTPSYYRGAQGVILVYDVTRRDTFVKL-DNWLNELETYCTRNDIVNMLVGNKIDKEN 128
           +  L P  Y     +++ + +   D+   + + W  E+  +C    I+  LVGNK D  N
Sbjct: 255 YDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVRHFCPNVPII--LVGNKKDLRN 82

Query: 129 REVDRNEGLKFARKHSML 146
            E  + E +K  ++   L
Sbjct: 81  DENTKRELMKMKQEPVRL 28
>07580
          Length = 921

 Score = 74.7 bits (182), Expect = 2e-14,   Method: Compositional matrix adjust.
 Identities = 45/123 (36%), Positives = 65/123 (52%), Gaps = 1/123 (0%)
 Frame = +3

Query: 48  KTISVDGNKAKLAIWDTAGQERFRTLTPSYYRGAQGVILVYDVTRRDTFVKLDNWLNELE 107
           K + VDG +  L I DTAG E+F  +   Y +  QG +L Y +T + TF  L     ++ 
Sbjct: 177 KQVEVDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFLLAYSITAQSTFNDLQELREQIL 356

Query: 108 TYCTRNDIVNMLVGNKIDKEN-REVDRNEGLKFARKHSMLFIEASAKTCDGVQCAFEELV 166
                +D+  +LVGNK D E+ R V +++G   AR  S  F+E SAK    V   F +LV
Sbjct: 357 RVKDTDDVPMLLVGNKCDLEDERVVGKDQGQGLARSFSCAFLETSAKARINVNEIFMDLV 536

Query: 167 EKI 169
            +I
Sbjct: 537 RQI 545
>35581
          Length = 364

 Score = 71.6 bits (174), Expect = 2e-13,   Method: Compositional matrix adjust.
 Identities = 37/95 (38%), Positives = 54/95 (56%), Gaps = 1/95 (1%)
 Frame = +2

Query: 9   LKILIIGESGVGKSSLLLRFTDDTF-DPELAATIGVDFKVKTISVDGNKAKLAIWDTAGQ 67
            K +++G++GVGK+ LL R   D F D  L +              G  A + +WDTAGQ
Sbjct: 47  FKCVLLGDAGVGKTCLLNRLATDKFLDSPLTSLTTASLLTTVTLTSGVMASVDLWDTAGQ 226

Query: 68  ERFRTLTPSYYRGAQGVILVYDVTRRDTFVKLDNW 102
           ER+R+LT SYYR  + V++VYD   +   +KL +W
Sbjct: 227 ERYRSLTSSYYRDTKAVLIVYDAEHK---LKLTDW 322
>01095
          Length = 1745

 Score = 70.9 bits (172), Expect = 3e-13,   Method: Compositional matrix adjust.
 Identities = 41/115 (35%), Positives = 66/115 (57%), Gaps = 1/115 (0%)
 Frame = -1

Query: 86   LVYDVTRRDTFVKLDNWLNELETYCTRNDIVNMLVGNKIDKEN-REVDRNEGLKFARKHS 144
            +VYD+T +DTF +   W+ EL+   + N IV  L GNK D  N R V+  E   +A ++S
Sbjct: 1745 VVYDITNQDTFGRAKTWVKELQRQASPN-IVIALAGNKADLANKRMVEFEEAQAYAEENS 1569

Query: 145  MLFIEASAKTCDGVQCAFEELVEKIIQTPGLWESENQNKGVKLSHREESRGGGAC 199
            +LF+E SAKT   V   F  + +K+ +  G   S+ + +GV+L++ +  +  G C
Sbjct: 1568 LLFMETSAKTAMNVNDIFLAIAKKLPKNEGGGGSQPRQQGVRLNNEQSQQSEGGC 1404
>00858
          Length = 1658

 Score = 70.1 bits (170), Expect = 6e-13,   Method: Compositional matrix adjust.
 Identities = 51/164 (31%), Positives = 86/164 (52%)
 Frame = -2

Query: 6    LTTLKILIIGESGVGKSSLLLRFTDDTFDPELAATIGVDFKVKTISVDGNKAKLAIWDTA 65
            +T  K++++G  GVGKS+L ++   + F  E   T   D   K + +DG    L I DTA
Sbjct: 1597 MTEYKLVVVGAGGVGKSALTIQLXQNHFVEEYDPTXE-DSXRKQVVIDGETCLLDILDTA 1421

Query: 66   GQERFRTLTPSYYRGAQGVILVYDVTRRDTFVKLDNWLNELETYCTRNDIVNMLVGNKID 125
            GQE    +     R  +G + V+ V    +F  ++ +  +++     +++  +LVGNK+D
Sbjct: 1420 GQEEXSAMRDQCMRTGEGFLCVFAVXNLKSFEDINQYREQIKRVKDADEVPMVLVGNKVD 1241

Query: 126  KENREVDRNEGLKFARKHSMLFIEASAKTCDGVQCAFEELVEKI 169
               R V++ +G   A  + + ++E SAKT  GV  AF  LV +I
Sbjct: 1240 LPIRNVEQRQGKHMAELYHIPYVETSAKTRQGVDDAFYTLVREI 1109
>12339
          Length = 578

 Score = 67.4 bits (163), Expect = 4e-12,   Method: Compositional matrix adjust.
 Identities = 46/138 (33%), Positives = 73/138 (52%), Gaps = 4/138 (2%)
 Frame = -2

Query: 67  QERFRTLTPSYYRGAQGVILVYDVTRRDTFVKLDNWLNELETYCTRNDIVN---MLVGNK 123
           QERF++L  ++YRGA   ILVYDVT   TF  LD+W  E     +  D  +   +++GNK
Sbjct: 577 QERFQSLGVAFYRGADCCILVYDVTEXKTFDSLDSWQREFLNQASPRDPEHFPFVVIGNK 398

Query: 124 IDKENREVDRNEGLKF-ARKHSMLFIEASAKTCDGVQCAFEELVEKIIQTPGLWESENQN 182
           ID +NR V    G  + + K  + + E SAK    V+ AF+ + +  +      E ++  
Sbjct: 397 IDLDNRVVTAKRGQGWCSTKGGIPYFETSAKEAINVEQAFQTVAKNALAQESEVEIDDFP 218

Query: 183 KGVKLSHREESRGGGACG 200
             ++LS+ ++SR    C 
Sbjct: 217 SEIRLSN-DDSRPRERCA 167
>27191
          Length = 443

 Score = 66.6 bits (161), Expect = 7e-12,   Method: Compositional matrix adjust.
 Identities = 30/104 (28%), Positives = 59/104 (56%)
 Frame = +1

Query: 21  KSSLLLRFTDDTFDPELAATIGVDFKVKTISVDGNKAKLAIWDTAGQERFRTLTPSYYRG 80
           K+ L+  F +  F+     T+GVD+  K  +V+G   ++ +WD +G   +  +    Y G
Sbjct: 1   KTCLIKHFCESKFNQGYQPTVGVDYGFKIQTVNGVDMRVHMWDLSGSNEYLDVRNELYTG 180

Query: 81  AQGVILVYDVTRRDTFVKLDNWLNELETYCTRNDIVNMLVGNKI 124
           +  + +V+DV+   +F  LD+WL E+  + T + + N++VGN++
Sbjct: 181 SDAIFIVFDVSNTPSFEALDSWLREINRFATGSPL-NVIVGNRV 309
>13745
          Length = 1045

 Score = 66.2 bits (160), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 45/144 (31%), Positives = 76/144 (52%), Gaps = 6/144 (4%)
 Frame = +2

Query: 67  QERFRTLTPSYYRGAQGVILVYDVTRRDTFVKLDNWLNELETYCTRNDIVN---MLVGNK 123
           QERF++L  ++YRGA   +LVYDVT  ++F  LD+W +E     +  D  +   +++GNK
Sbjct: 2   QERFQSLGVAFYRGADCCVLVYDVTAPNSFKNLDSWRDEFLIQASPRDPEHFPFVVLGNK 181

Query: 124 IDKENREVDRNEGLKFAR-KHSMLFIEASAKTCDGVQCAFEELVEKIIQTPGLWESENQN 182
           +D +NR+V      ++ + K+ + + E SAK    V+ AF+ + +  ++     E  N  
Sbjct: 182 VDLDNRQVSTRRAQQWCQSKNDIPYYETSAKEGINVEMAFQTIAKNALEQETEAELINDF 361

Query: 183 KGVKLSHREESRGGGA--CGGYCS 204
                 + E +R G A  C   CS
Sbjct: 362 PDQIRLNSENNRPGNADNCQC*CS 433
>11728
          Length = 635

 Score = 65.5 bits (158), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 36/127 (28%), Positives = 65/127 (51%), Gaps = 2/127 (1%)
 Frame = -1

Query: 6   LTTLKILIIGESGVGKSSLLLRFTDDTFDPELAATIGVDFKVKTISVDGNKAKLAIWDTA 65
           +  +K +++G+  VGK+ LL+ +T + F  E   T+  ++    + VD     L +WDTA
Sbjct: 497 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSA-NVMVDSKPINLGLWDTA 321

Query: 66  GQERFRTLTPSYYRGAQGVILVYDVTRRDTFVKLD-NWLNELETYCTRNDIVNMLVGNKI 124
           GQE +  L P  Y      ++ + +    +F  +   W  E+  +C    I+  LVG K+
Sbjct: 320 GQEDYDRLRPLSYPQTDVFLICFSLISPASFENVKAKWYPEVSHHCPNTPII--LVGTKL 147

Query: 125 D-KENRE 130
           D +E++E
Sbjct: 146 DLREDKE 126
>26536
          Length = 829

 Score = 63.9 bits (154), Expect = 4e-11,   Method: Compositional matrix adjust.
 Identities = 39/111 (35%), Positives = 56/111 (50%), Gaps = 1/111 (0%)
 Frame = +2

Query: 63  DTAGQERFRTLTPSYYRGAQGVILVYDVTRRDTFVKLDNWLNELETYCTRNDIVNMLVGN 122
           DTAGQE + ++   Y R   G I+VY VT   +F + +     L  +     I  +L GN
Sbjct: 146 DTAGQEEYSSMREHYTRSGDGFIVVYSVTDVTSFQEAEAVFRWLTRFQDETSIHAVLCGN 325

Query: 123 KID-KENREVDRNEGLKFARKHSMLFIEASAKTCDGVQCAFEELVEKIIQT 172
           K D   +R+V   EG K A +  ML+ E SAKT D V   +  L+  I ++
Sbjct: 326 KTDLTSDRKVTPEEGRKMADRLGMLYFETSAKTGDNVSQVYHGLLRSIPRS 478

 Score = 39.3 bits (90), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 23/49 (46%), Positives = 29/49 (59%)
 Frame = +2

Query: 7   TTLKILIIGESGVGKSSLLLRFTDDTFDPELAATIGVDFKVKTISVDGN 55
           T  KI+++G  GVGKSSL +RFT DTF      TI   ++ K I V G 
Sbjct: 482 TDYKIVMLGSGGVGKSSLTIRFTQDTFLDVYDPTIEDSYR-KMIQVSGQ 625
>34359
          Length = 1042

 Score = 63.9 bits (154), Expect = 5e-11,   Method: Compositional matrix adjust.
 Identities = 37/109 (33%), Positives = 58/109 (53%)
 Frame = +3

Query: 36  ELAATIGVDFKVKTISVDGNKAKLAIWDTAGQERFRTLTPSYYRGAQGVILVYDVTRRDT 95
           +  AT+GV+      +      +  +WDTAGQE+F  L   YY      I+++DVT R T
Sbjct: 132 KYVATLGVEVHPLQFNTSRGLLRFNVWDTAGQEKFGGLRDGYYIQGTCAIIMFDVTSRVT 311

Query: 96  FVKLDNWLNELETYCTRNDIVNMLVGNKIDKENREVDRNEGLKFARKHS 144
           +  + NW  +L   C    IV  L GNK+D ++R+V + + + F RK +
Sbjct: 312 YKNVPNWHRDLVRVCENIPIV--LCGNKVDIKDRKV-KAKAIVFHRKRT 449
>13750
          Length = 503

 Score = 62.0 bits (149), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 48/150 (32%), Positives = 68/150 (45%), Gaps = 5/150 (3%)
 Frame = -2

Query: 21  KSSLLLRFTDDTFDPELAATIGV---DFKVKTISVDGNKAKLAIWDTAGQERFRTLTPSY 77
           K+ LL R+    F      TI V   +F       D    +  +WDT G E +R+L  S+
Sbjct: 502 KTCLLRRYQKGFFMDRTMPTIAVLCSEFNES--RTDPLNVRYTLWDTGGAETYRSLWVSH 329

Query: 78  YRGAQGVILVYDVTRRDTFVKLDN-WLNELETYCTRNDIVNMLVGNKID-KENREVDRNE 135
           +RGAQ  +LVYDVT   +F+     W   L        ++   VG+K D +ENR +    
Sbjct: 328 FRGAQVALLVYDVTCEWSFLTATTVWRKALMKNIPEAQVI--FVGSKTDLEENRVISTER 155

Query: 136 GLKFARKHSMLFIEASAKTCDGVQCAFEEL 165
           G  FA +    F E S+ T   V   F E+
Sbjct: 154 GQAFATQCGYTFFETSSVTGKNVDAVFWEI 65
>19656
          Length = 428

 Score = 61.6 bits (148), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 32/106 (30%), Positives = 52/106 (49%), Gaps = 1/106 (0%)
 Frame = +3

Query: 6   LTTLKILIIGESGVGKSSLLLRFTDDTFDPELAATIGVDFKVKTISVDGNKAKLAIWDTA 65
           +  +K +++G+  VGK+ LL+ +T + F  E   T+  D     + VDG    L +WDTA
Sbjct: 105 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTV-FDNYSANVMVDGRPVNLGLWDTA 281

Query: 66  GQERFRTLTPSYYRGAQGVILVYDVTRRDTFVKL-DNWLNELETYC 110
           GQE +  L P  Y      +L + V    +F  +   W  E+  +C
Sbjct: 282 GQEDYDRLRPLSYPQTDVFLLCFSVASPASFENIRAKWYPEVNHHC 419
>29380
          Length = 853

 Score = 59.7 bits (143), Expect = 8e-10,   Method: Compositional matrix adjust.
 Identities = 41/121 (33%), Positives = 61/121 (50%), Gaps = 2/121 (1%)
 Frame = -2

Query: 81  AQGVILVYDVTRRDTFVKLDNWLNELETYCTRNDIVNMLVGNKID--KENREVDRNEGLK 138
           A   I+VYDV   DTF +   W+ EL    T + ++ +L GNK+D   ++R V   +   
Sbjct: 852 ASAAIIVYDVNIADTFSRALAWVKELRQQNTESVLI-ILAGNKVDLATQHRAVSFEDAQS 676

Query: 139 FARKHSMLFIEASAKTCDGVQCAFEELVEKIIQTPGLWESENQNKGVKLSHREESRGGGA 198
           FAR++ +LF E SAKT   V   F  L  ++IQ        ++N+GV L+       G  
Sbjct: 675 FARENGLLFAEVSAKTGMAVNEIFMTLANQLIQQE---IDGSRNRGVTLNRENGEASGCK 505

Query: 199 C 199
           C
Sbjct: 504 C 502
>34597
          Length = 773

 Score = 51.2 bits (121), Expect(2) = 1e-08,   Method: Compositional matrix adjust.
 Identities = 36/117 (30%), Positives = 62/117 (52%), Gaps = 3/117 (2%)
 Frame = -2

Query: 93  RDTFVKLDNWLNELETYCTRNDIVNMLVGNKID-KENREVDRNEGLKFARKHSMLFIEAS 151
           + +F  +  WL  ++ +    D+  M++GNK D  + R V +  G   AR+HS+ F+E S
Sbjct: 715 KKSFENIVKWLRNIDEH-ANEDVEKMILGNKCDMTDKRVVSKERGEAIAREHSIRFMETS 539

Query: 152 AKTCDGVQCAFEELVEKII-QTPGLWESENQNKGV-KLSHREESRGGGACGGYCSVL 206
           AK+   ++ AF EL E I+ +T G   +EN  + V    + +++ G   C   C V+
Sbjct: 538 AKSNINIERAFCELAEAILDKTAGRESAENPERVVIDRGNSDKAPGYNKCCA*CGVM 368

 Score = 24.3 bits (51), Expect(2) = 1e-08,   Method: Compositional matrix adjust.
 Identities = 9/12 (75%), Positives = 11/12 (91%)
 Frame = -3

Query: 76  SYYRGAQGVILV 87
           SYYRGA G++LV
Sbjct: 768 SYYRGAMGIMLV 733
>00552
          Length = 455

 Score = 49.7 bits (117), Expect = 9e-07,   Method: Compositional matrix adjust.
 Identities = 23/46 (50%), Positives = 33/46 (71%)
 Frame = -1

Query: 9   LKILIIGESGVGKSSLLLRFTDDTFDPELAATIGVDFKVKTISVDG 54
           LK++++G+ GVGKSSL+ RF  + FD +   TIGV+F  K + VDG
Sbjct: 443 LKVVLLGDGGVGKSSLMNRFVSNKFDAQSFHTIGVEFLTKDVVVDG 306

 Score = 46.2 bits (108), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 22/67 (32%), Positives = 35/67 (52%), Gaps = 1/67 (1%)
 Frame = -3

Query: 44  DFKVKT-ISVDGNKAKLAIWDTAGQERFRTLTPSYYRGAQGVILVYDVTRRDTFVKLDNW 102
           D K+ T ++   +     IWDTAGQER+++L   +YRG    +L + V    +   L +W
Sbjct: 201 DIKMDTLVAASPDVWHHGIWDTAGQERYKSLRTPFYRGTDCCLLTFSVDNLKSLQSLSDW 22

Query: 103 LNELETY 109
            +E   Y
Sbjct: 21  YDEFVNY 1
>09827
          Length = 1201

 Score = 47.8 bits (112), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 41/173 (23%), Positives = 72/173 (41%), Gaps = 5/173 (2%)
 Frame = -3

Query: 9    LKILIIGESGVGKSSLLLRFTDDTFDPELAATIG-VDFKVKTISVDGNKAKLAIWDTAGQ 67
            ++IL++G    GK+++L +        E+  TI  + F V+T  V+       +WD  GQ
Sbjct: 1112 MRILMVGLDAAGKTTILYKLKLG----EIVTTIPTIGFNVET--VEYKNISFTVWDVGGQ 951

Query: 68   ERFRTLTPSYYRGAQGVILVYDVTRRDTFVKLDNWLNELETYCTRNDIVNMLVGNKIDKE 127
            ++ R L   Y++  QG+I V D   ++   +    L  +       D V ++  NK D  
Sbjct: 950  DKIRPLWRHYFQNTQGLIFVVDSNDKERVQEAREELTRMLNEDELRDAVLLVFANKQDLP 771

Query: 128  N----REVDRNEGLKFARKHSMLFIEASAKTCDGVQCAFEELVEKIIQTPGLW 176
            +     E+    GL   R  +       A T DG+    + L  ++      W
Sbjct: 770  HAMATAEITEKLGLHGLRNRTWYIQSTCATTGDGLYEGLDWLSNQLKNNKS*W 612
>08153
          Length = 1703

 Score = 47.0 bits (110), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 41/162 (25%), Positives = 69/162 (42%), Gaps = 5/162 (3%)
 Frame = +1

Query: 9   LKILIIGESGVGKSSLLLRFTDDTFDPELAATIG-VDFKVKTISVDGNKAKLAIWDTAGQ 67
           ++IL++G    GK+++L +        E+  TI  + F V+T  V+       +WD  GQ
Sbjct: 85  VRILMVGLDAAGKTTILYKLKLG----EIVTTIPTIGFNVET--VEYKNISFTVWDVGGQ 246

Query: 68  ERFRTLTPSYYRGAQGVILVYDVTRRDTFVKLDNWLNELETYCTRNDIVNMLVGNKIDKE 127
           ++ R L   Y++  QG+I V D   R+   +    L  +       D + ++  NK D  
Sbjct: 247 DKIRPLWRHYFQNTQGLIFVVDSNDRERINEAKEELARMLNEDDLRDAIILVFANKQDLP 426

Query: 128 N----REVDRNEGLKFARKHSMLFIEASAKTCDGVQCAFEEL 165
           N     EV  + GL   +          A + DG+    E L
Sbjct: 427 NAYSASEVTAHLGLANLKGRKWYMQATCATSGDGMYEGLEWL 552
>33605
          Length = 888

 Score = 45.8 bits (107), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 25/85 (29%), Positives = 47/85 (55%)
 Frame = +1

Query: 9   LKILIIGESGVGKSSLLLRFTDDTFDPELAATIGVDFKVKTISVDGNKAKLAIWDTAGQE 68
           +++L++G    GK+++L +F  +  D  ++ T+G  F +KT+   G   KL +WD  GQ+
Sbjct: 499 VRLLMLGLDNAGKTTILKKFNGEDIDT-ISPTLG--FNIKTLEHRG--FKLNVWDVGGQQ 663

Query: 69  RFRTLTPSYYRGAQGVILVYDVTRR 93
             R+   +Y+    G++ V D   R
Sbjct: 664 SLRSYWRNYFESTDGLVWVVDSADR 738
>14775
          Length = 380

 Score = 45.8 bits (107), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 28/74 (37%), Positives = 38/74 (51%), Gaps = 3/74 (4%)
 Frame = -2

Query: 21  KSSLLLRFTDDTFDPELAATIGV---DFKVKTISVDGNKAKLAIWDTAGQERFRTLTPSY 77
           K+ LL R+    F      TI V   +F       D    +  +WDT G E +R+L  S+
Sbjct: 379 KTCLLRRYQKGFFMDRTMPTIAVLCSEFNES--RTDPLNVRYTLWDTGGAETYRSLWVSH 206

Query: 78  YRGAQGVILVYDVT 91
           +RGAQ  +LVYDVT
Sbjct: 205 FRGAQVALLVYDVT 164
>10862
          Length = 2896

 Score = 44.7 bits (104), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 29/117 (24%), Positives = 50/117 (42%), Gaps = 4/117 (3%)
 Frame = -3

Query: 46   KVKTISVDGNKAKLAIWDTAGQERFRTLTPSYYRGAQGVILVYDVTRRDTFVKLDNWLNE 105
            +++  +    + +  +WD  GQ++ R L   YY G QG+I V D   RD   +    L+ 
Sbjct: 2519 RIQCRNCQLQECQFNVWDVGGQDKIRPLWRHYYTGTQGLIFVVDCADRDRIDEARQELHR 2340

Query: 106  LETYCTRNDIVNMLVGNKIDKEN----REVDRNEGLKFARKHSMLFIEASAKTCDGV 158
            +       D + ++  NK D  +     E+    GL   R  +     + A T DG+
Sbjct: 2339 IINDREMRDAIILIFANKQDLPDAMKPHEIQEKLGLTRLRDRNWYVQPSCATTGDGL 2169
>31291
          Length = 446

 Score = 44.3 bits (103), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 37/124 (29%), Positives = 59/124 (47%), Gaps = 16/124 (12%)
 Frame = -1

Query: 59  LAIWDTAGQERFRTLTPSYYRGAQGVILVYDVTRRDTF--VKLDNWLNELETYCTRNDIV 116
           L +WDTAGQE +  L P  Y      +L + +    +   VK+  W  E+  +     IV
Sbjct: 446 LQLWDTAGQEDYDRLRPLAYPNTDVFMLXFSLMSEASMKNVKV-KWYPEIRHHDPHVPIV 270

Query: 117 NMLVGNKID-KENRE------------VDRNEGLKFARK-HSMLFIEASAKTCDGVQCAF 162
             LVG K+D ++++E            V  N+G   A+   +  + E S+KT + ++ AF
Sbjct: 269 --LVGTKLDLRQDKEAVRKLRSSRQDPVSSNQGNDLAKAIKAKRYFECSSKTQENLKTAF 96

Query: 163 EELV 166
           EE V
Sbjct: 95  EETV 84
>18509
          Length = 625

 Score = 43.5 bits (101), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 22/57 (38%), Positives = 35/57 (61%)
 Frame = -3

Query: 113 NDIVNMLVGNKIDKENREVDRNEGLKFARKHSMLFIEASAKTCDGVQCAFEELVEKI 169
           +++  +LVGNK+D   R V++ +G   A  + + ++E SAKT  GV  AF  LV +I
Sbjct: 533 DEVPMVLVGNKVDLPIRNVEQRQGKHMAELYHIPYVETSAKTRQGVDDAFYTLVREI 363
>09204
          Length = 1051

 Score = 43.5 bits (101), Expect = 6e-05,   Method: Compositional matrix adjust.
 Identities = 28/108 (25%), Positives = 50/108 (46%), Gaps = 5/108 (4%)
 Frame = -3

Query: 69   RFRTLTPSYYRGAQGVILVYDVTRRDTFVKLDNWLNELETYCTRNDIVNMLVGNKI---- 124
            R+  ++  YYRGA+  IL +D+T + +F ++  W+ EL  +    +    + G K     
Sbjct: 1049 RYEAMSRIYYRGAKAAILCFDLTDKSSFDRIRFWIGELRQH--EEECKLYICGTKFDLVH 876

Query: 125  -DKENREVDRNEGLKFARKHSMLFIEASAKTCDGVQCAFEELVEKIIQ 171
             D E R V R+     A        E S+ T D ++  F ++ E  ++
Sbjct: 875  DDPERRAVPRSVAKALADDCMAEIYETSSMTGDNIEKLFTKIAEDYMK 732
>31928
          Length = 429

 Score = 35.8 bits (81), Expect = 0.011,   Method: Compositional matrix adjust.
 Identities = 21/73 (28%), Positives = 37/73 (50%), Gaps = 3/73 (4%)
 Frame = +2

Query: 54  GNKAKLAIWDTAGQERFRT---LTPSYYRGAQGVILVYDVTRRDTFVKLDNWLNELETYC 110
           G K K+ I+DT       T   L   Y     G +LVYD T  ++F +LD    +++ + 
Sbjct: 95  GVKEKVRIFDTGAAALETTEGDLPKHYLNFPDGFVLVYDTTSWESFRRLDKLKKDIDKHR 274

Query: 111 TRNDIVNMLVGNK 123
            + ++  +++GNK
Sbjct: 275 DKREVHMIVIGNK 313
>10708
          Length = 2775

 Score = 35.0 bits (79), Expect = 0.022,   Method: Compositional matrix adjust.
 Identities = 13/42 (30%), Positives = 23/42 (54%)
 Frame = -2

Query: 55   NKAKLAIWDTAGQERFRTLTPSYYRGAQGVILVYDVTRRDTF 96
             + +LA+WDTAGQE +  L P  Y     +++ + +   D+ 
Sbjct: 2729 QQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSL 2604
>31932
          Length = 437

 Score = 32.7 bits (73), Expect = 0.11,   Method: Compositional matrix adjust.
 Identities = 34/97 (35%), Positives = 49/97 (50%), Gaps = 11/97 (11%)
 Frame = -1

Query: 118 MLVGNKIDKENREVDRNEGLKFARKHSML-FIEASAKTCDG------VQCAFEELVEKII 170
           +L+GNK D  +REV+++E     ++H  L + E S K  DG      +    EE++ K  
Sbjct: 392 LLLGNKSDLGHREVEQDEIEDLCKEHDFLGWSETSVK--DGTMIDESMNYLIEEMMAKHA 219

Query: 171 QTPGLWESENQNKGV--KLSHREES--RGGGACGGYC 203
           +  G  ES  Q  GV  +LS RE+S    G  CG  C
Sbjct: 218 ELEGFSESVTQGNGVIRRLS-REDSDVPSGSRCGC*C 111
>30917
          Length = 1616

 Score = 28.9 bits (63), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 12/25 (48%), Positives = 16/25 (64%)
 Frame = +3

Query: 175  LWESENQNKGVKLSHREESRGGGAC 199
            LW++ NQN+ V L +REE  G G  
Sbjct: 1110 LWKAPNQNQTVPLKNREELHGPGGV 1184
>34156
          Length = 348

 Score = 28.5 bits (62), Expect = 1.8,   Method: Compositional matrix adjust.
 Identities = 19/63 (30%), Positives = 33/63 (52%), Gaps = 9/63 (14%)
 Frame = -1

Query: 11  ILIIGESGVGKSSLL--LRFTD-------DTFDPELAATIGVDFKVKTISVDGNKAKLAI 61
           ++++GESG+GKS+L+  L  TD        +   ++  T+ +D     I   G K +L +
Sbjct: 189 LMVVGESGLGKSTLVNSLFLTDLYPERHIPSASEKIQQTVKIDASTVEIEERGVKLRLTV 10

Query: 62  WDT 64
            DT
Sbjct: 9   VDT 1
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|15809036|ref|NP_291092.1| phosphodiesterase 6C, cGMP
specific, cone, alpha prime [Mus musculus]
         (861 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

28167                                                                 142   6e-34
13617                                                                  49   6e-06
28476                                                                  40   0.004
16973                                                                  35   0.12 
16955                                                                  35   0.14 
13996                                                                  32   1.2  
>28167
          Length = 587

 Score =  142 bits (358), Expect = 6e-34,   Method: Compositional matrix adjust.
 Identities = 71/148 (47%), Positives = 99/148 (66%)
 Frame = +2

Query: 670 IATDLALYFKKRTMFQKIVDTCEQMQSEEETIKYVTSDPTKKEVIMAMMMTACDLSAITK 729
           +ATDLALYF+ R  F  +  + E        + +  SD   ++++ +MMMTA D++AITK
Sbjct: 2   LATDLALYFRYRGRFFDLTKSPE--------VNW--SDDCNRDLLRSMMMTASDVAAITK 151

Query: 730 PWEVQSQVALLVANEFWEQGDLERTVLQQQPIPMMDRSKKDELPKLQVGFIDFVCTFVYK 789
           PWEVQ +VA LV+ EF+EQGD+E+  L+ QP+ MMDR KKD+LP +QVGFID +C  VY+
Sbjct: 152 PWEVQKKVAHLVSREFFEQGDMEKETLKIQPMEMMDREKKDKLPNMQVGFIDTICLPVYE 331

Query: 790 EFSRFHGEITPMLNGLQNNRVEWKSLAE 817
             +R    ++P+L G Q NR  W S AE
Sbjct: 332 AMTRVSPRLSPLLKGCQQNRDHWMSEAE 415
>13617
          Length = 465

 Score = 49.3 bits (116), Expect = 6e-06,   Method: Compositional matrix adjust.
 Identities = 37/151 (24%), Positives = 75/151 (49%)
 Frame = +2

Query: 385 KNVLSLPIVNKKEDIVGVATFYNRKDGKPFDEHDEHITETLTQFLGWSLLNTDTYERVNK 444
           K +L +PI N    ++GV    N+ D   F+++DE++ E    F G  + NT  YE   K
Sbjct: 80  KCILCMPIKNVAGKVIGVMQLINKLDNTAFNKNDENLFEAFAIFCGMGINNTSMYETAMK 259

Query: 445 LESRKDIAQEMVMNLTKATPDEISSILKFKEKLNVEVIEECEERQLLAILKEDLPDPRTA 504
             +++ +A E VM+     P                 +EE E+ +++ +     P  +  
Sbjct: 260 AIAKQRVALE-VMSYHAMAP-----------------MEEAEKLKMMPV-----PTSQQY 370

Query: 505 DLYEFCFSDFPITEHELVKCGLRLFLEINVV 535
           +L ++ FSDF + + + +K  +R+F++++++
Sbjct: 371 NLLDYTFSDFTLDDDDTLKATIRMFMDLDLI 463
>28476
          Length = 1475

 Score = 40.0 bits (92), Expect = 0.004,   Method: Composition-based stats.
 Identities = 18/57 (31%), Positives = 30/57 (52%)
 Frame = -3

Query: 521 LVKCGLRLFLEINVVEKFKVPVEVLTRWMYTVRKGYRPVTYHNWRHGFNVGQTMFTL 577
           L K   +LF E+ ++E F++PV     + + +  GYR   YHN  H  +V   ++ L
Sbjct: 201 LSKVAYKLFTEVGLMETFRIPVVEFINYFHALELGYREKPYHNRVHATDVLHGVYYL 31
>16973
          Length = 1511

 Score = 35.0 bits (79), Expect = 0.12,   Method: Compositional matrix adjust.
 Identities = 13/26 (50%), Positives = 20/26 (76%)
 Frame = +2

Query: 785  TFVYKEFSRFHGEITPMLNGLQNNRV 810
             F+ +EFSRFH +ITP++   Q+NR+
Sbjct: 1067 NFILREFSRFHKQITPLIVRHQSNRI 1144
>16955
          Length = 862

 Score = 35.0 bits (79), Expect = 0.14,   Method: Composition-based stats.
 Identities = 13/25 (52%), Positives = 20/25 (80%)
 Frame = +1

Query: 786 FVYKEFSRFHGEITPMLNGLQNNRV 810
           F+ +EFSRFH +ITP++   Q+NR+
Sbjct: 640 FILREFSRFHKQITPLIVRHQSNRI 714
>13996
          Length = 515

 Score = 32.0 bits (71), Expect = 1.2,   Method: Composition-based stats.
 Identities = 12/23 (52%), Positives = 18/23 (78%)
 Frame = +1

Query: 767 SKKDELPKLQVGFIDFVCTFVYK 789
           S++ +LP +QVGFID +C  VY+
Sbjct: 325 SRRTKLPTMQVGFIDSICLPVYE 393
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|29789028|ref|NP_071707.1| tenascin R [Mus musculus]
         (1358 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

14071                                                                 143   6e-34
15778                                                                 127   3e-29
12770                                                                 101   3e-21
08563                                                                  91   3e-18
07364                                                                  84   3e-16
37574                                                                  73   5e-15
20469                                                                  72   1e-12
29222                                                                  61   3e-09
14044                                                                  55   2e-07
13194                                                                  54   3e-07
37687                                                                  52   1e-06
14608                                                                  50   5e-06
33896                                                                  42   0.002
19486                                                                  39   0.015
26257                                                                  38   0.021
14158                                                                  36   0.093
12576                                                                  36   0.13 
19200                                                                  35   0.29 
09025                                                                  33   0.67 
26039                                                                  32   1.3  
08926                                                                  32   1.3  
17679                                                                  32   2.4  
07945                                                                  32   2.6  
38764                                                                  31   3.1  
15692                                                                  30   6.3  
>14071
          Length = 875

 Score =  143 bits (360), Expect = 6e-34,   Method: Compositional matrix adjust.
 Identities = 76/184 (41%), Positives = 112/184 (60%), Gaps = 5/184 (2%)
 Frame = +1

Query: 1164 LQVYCDMTTDGGGWIVFQRRQNGQTDFFRKWADYRVGFGNLEDEFWLGLDNIHRITAQGR 1223
              V CD  T G GW V QRR NG  +F+R W++YR GFG+LE EF++GL+ ++ +T    
Sbjct: 241  FMVLCDGHTAGSGWTVVQRRFNGTVNFYRSWSEYREGFGDLEGEFFIGLEKLYYMTKSQP 420

Query: 1224 YELRVDMRDGQ-EAVFAYYDKFAVEDSRSLYKIR-IGSYNGTAGDSLSYHQGRPFSTEDR 1281
            YEL +++ D + E   A YD F + +    Y ++ +G+Y G AG++L+++    F+T DR
Sbjct: 421  YELYIELVDFKGEVRHALYDNFLIGNEEEQYMLKSLGTYLGNAGNALAFNLHDKFTTYDR 600

Query: 1282 DND-VAVTNCAMSYKGAWWYKNCHRTNLNGKYGESR--HSQGINWYHWKGHEFSIPFVEM 1338
            D+D     NCA  Y+  WWY     +NLNGKY ES   + + I W+ WKG+ FS+  V M
Sbjct: 601  DHDGWGAGNCADWYESGWWYNLHGNSNLNGKYFESEVLNHKSIWWHTWKGY-FSLKSVRM 777

Query: 1339 KMRP 1342
             +RP
Sbjct: 778  LIRP 789
>15778
          Length = 446

 Score =  127 bits (319), Expect = 3e-29,   Method: Composition-based stats.
 Identities = 60/135 (44%), Positives = 83/135 (61%), Gaps = 3/135 (2%)
 Frame = -3

Query: 1181 QRRQNGQTDFFRKWADYRVGFGNLEDEFWLGLDNIHRITAQGRYELRVDMRDGQEAVF-A 1239
            QRR +G  DF+  W  Y  GFG  +  +W+GL+ +H++T+ G YELRVD++D  + +  A
Sbjct: 405  QRRVDGSQDFYLGWDQYVTGFGRNDSNYWMGLEPLHQLTSGGIYELRVDLKDWNDVMASA 226

Query: 1240 YYDKFAVEDSRSLYKIRIGSY-NGTAGDSLSYHQGRPFSTEDRDNDVAVT-NCAMSYKGA 1297
             Y  F +  +   YK+    +  G AGDSLS HQ  PFST+D D+D+A T +CA  Y G 
Sbjct: 225  NYSNFVIGGADDXYKLYYDQFIGGDAGDSLSKHQHMPFSTKDADHDLAFTGSCADWYHGG 46

Query: 1298 WWYKNCHRTNLNGKY 1312
            WWY  C   NLNG+Y
Sbjct: 45   WWYNACQDANLNGRY 1
>12770
          Length = 465

 Score =  101 bits (251), Expect = 3e-21,   Method: Composition-based stats.
 Identities = 58/143 (40%), Positives = 80/143 (55%), Gaps = 6/143 (4%)
 Frame = +2

Query: 1207 EFWLGLDNIHRITAQGRYELRVDMRD-GQEAVFAYYDKFAVEDSRSLYKIRIGSY-NGTA 1264
            E+WLGL  IH +T+ G + LR+DM D         Y  F V      Y++   +Y  GTA
Sbjct: 32   EYWLGLQRIHEMTSLGYWLLRIDMEDWNGNTALVVYSGFKVGPEIDGYRMTFSNYMGGTA 211

Query: 1265 GDSLSYHQGRPFSTEDRDND-VAVTNCAMSYKGAWWYKNCHRTNLNGKYGESRHS---QG 1320
            GD+L+  + + F+T DRD+D  A  NCA   +G WWYK C  +NLNGKY  S  +   +G
Sbjct: 212  GDALAAQKNQAFTTRDRDHDQNANANCAALNEGGWWYKTCTHSNLNGKYIPSSQTTDYRG 391

Query: 1321 INWYHWKGHEFSIPFVEMKMRPY 1343
            + W  WKG  +S+    MK+ PY
Sbjct: 392  LIWSSWKGINYSLKRSVMKILPY 460
>08563
          Length = 817

 Score = 90.9 bits (224), Expect = 3e-18,   Method: Composition-based stats.
 Identities = 42/108 (38%), Positives = 67/108 (62%), Gaps = 4/108 (3%)
 Frame = +2

Query: 1238 FAYYDKFAVEDSRSLYKIRIGSY-NGTAGDSLSYHQGRPFSTEDRDNDVAVTNCAMSYKG 1296
            +A Y  F V  +   Y++    Y  GTAGD+L+ H  RPF+T+DRD+  +   CA  YKG
Sbjct: 11   YALYADFKVGSATDSYRMTYSRYIEGTAGDALAIHNERPFTTKDRDDPSSF--CAREYKG 184

Query: 1297 AWWYKNCHRTNLNGKYGES---RHSQGINWYHWKGHEFSIPFVEMKMR 1341
            AWW+ NC +++LNG+Y  S   ++++G+ W +W G  +S+    M++R
Sbjct: 185  AWWFDNCFQSHLNGQYKNSENNKYAEGLIWLNWHGISYSLKTTVMQIR 328
>07364
          Length = 985

 Score = 84.3 bits (207), Expect = 3e-16,   Method: Composition-based stats.
 Identities = 50/141 (35%), Positives = 68/141 (48%), Gaps = 5/141 (3%)
 Frame = -1

Query: 188 CICNEGWFGKNCSEPYCPLGCSSRGVCV-DGQCICDSEYSGDDCSELRCPTDCSSRGLCV 246
           C C +G+ G+ C  P C  GC + G CV   +C C S Y G  C + RC   C + G C+
Sbjct: 775 CRCAKGYKGRYCETPVCGRGCVNGGKCVAPRRCSCPSGYRGRRCQKPRCRPSCKNGGKCI 596

Query: 247 -DGECVCEEPYTGEDCRELRCPGDCSGKGQC-ANGTCLCQEGYAGEDCSQRRCLNAC--S 302
             G C+C     G  CR   C   C   G+C ANG CLC   + G  C + +C   C   
Sbjct: 595 APGICLCPPSLLGPRCRRHTCRKKCRNGGRCVANGKCLCPPSFYGRYCHRAKCNLTCLNG 416

Query: 303 GRGHCQEGLCICEEGYQGPDC 323
           GR   ++  C C +G++G  C
Sbjct: 415 GRCRRRKNRCRCPKGFRGRRC 353

 Score = 82.0 bits (201), Expect = 2e-15,   Method: Composition-based stats.
 Identities = 46/140 (32%), Positives = 61/140 (43%), Gaps = 4/140 (2%)
 Frame = -1

Query: 188 CICNEGWFGKNCSEPYCPLGCSSRGVC-VDGQCICDSEYSGDDCSELRCPTDCSSRGLCV 246
           C C   + G +C  P+C   C + G C +   C C   Y+G DC    C   C + G C+
Sbjct: 964 CHCPHNFTGLSCETPHCDPPCLNGGYCTMTAVCACPYGYTGVDCQPY-CHKTCHNGGQCI 788

Query: 247 DGE-CVCEEPYTGEDCRELRCPGDCSGKGQC-ANGTCLCQEGYAGEDCSQRRCLNACSGR 304
             + C C + Y G  C    C   C   G+C A   C C  GY G  C + RC  +C   
Sbjct: 787 RHDRCRCAKGYKGRYCETPVCGRGCVNGGKCVAPRRCSCPSGYRGRRCQKPRCRPSCKNG 608

Query: 305 GHC-QEGLCICEEGYQGPDC 323
           G C   G+C+C     GP C
Sbjct: 607 GKCIAPGICLCPPSLLGPRC 548

 Score = 63.9 bits (154), Expect = 5e-10,   Method: Composition-based stats.
 Identities = 39/114 (34%), Positives = 47/114 (41%), Gaps = 4/114 (3%)
 Frame = -1

Query: 214 CVD-GQCICDSEYSGDDCSELRCPTDCSSRGLC-VDGECVCEEPYTGEDCRELRCPGDCS 271
           CV  G C C   ++G  C    C   C + G C +   C C   YTG DC+   C   C 
Sbjct: 982 CVSPGLCHCPHNFTGLSCETPHCDPPCLNGGYCTMTAVCACPYGYTGVDCQPY-CHKTCH 806

Query: 272 GKGQCA-NGTCLCQEGYAGEDCSQRRCLNACSGRGHC-QEGLCICEEGYQGPDC 323
             GQC  +  C C +GY G  C    C   C   G C     C C  GY+G  C
Sbjct: 805 NGGQCIRHDRCRCAKGYKGRYCETPVCGRGCVNGGKCVAPRRCSCPSGYRGRRC 644
>37574
          Length = 433

 Score = 63.5 bits (153), Expect(2) = 5e-15,   Method: Composition-based stats.
 Identities = 27/76 (35%), Positives = 38/76 (50%)
 Frame = -3

Query: 256 YTGEDCRELRCPGDCSGKGQCANGTCLCQEGYAGEDCSQRRCLNACSGRGHCQEGLCICE 315
           +TG DC    C   C   G C N  C+C +G+ G  C Q +C   C   G C  G C+C+
Sbjct: 257 FTGPDCETEVCRLVCV-HGHCRNQRCVCAQGWTGALCDQLQCDRRCHAHGFCSNGSCVCD 81

Query: 316 EGYQGPDCSAVAPPED 331
           +G+ G  C+    P+D
Sbjct: 80  KGWNGKHCTINGCPKD 33

 Score = 37.0 bits (84), Expect(2) = 5e-15,   Method: Compositional matrix adjust.
 Identities = 24/57 (42%), Positives = 29/57 (50%), Gaps = 10/57 (17%)
 Frame = -1

Query: 208 CSSRGVCVDGQCICDSEYSGDDCS-------ELRCPTDCSSRGLCVD---GECVCEE 254
           CS +GVC+ GQC C + + G DCS        L C  +CS  GL  D   G C CE 
Sbjct: 427 CSGQGVCLHGQCRCFNGFKGSDCSLADKINVTLVCAKNCSGHGL-YDLDLGTCRCER 260

 Score = 72.8 bits (177), Expect = 8e-13,   Method: Composition-based stats.
 Identities = 30/81 (37%), Positives = 45/81 (55%)
 Frame = -3

Query: 196 GKNCSEPYCPLGCSSRGVCVDGQCICDSEYSGDDCSELRCPTDCSSRGLCVDGECVCEEP 255
           G +C    C L C   G C + +C+C   ++G  C +L+C   C + G C +G CVC++ 
Sbjct: 251 GPDCETEVCRLVCV-HGHCRNQRCVCAQGWTGALCDQLQCDRRCHAHGFCSNGSCVCDKG 75

Query: 256 YTGEDCRELRCPGDCSGKGQC 276
           + G+ C    CP DCSG G+C
Sbjct: 74  WNGKHCTINGCPKDCSGHGEC 12

 Score = 72.4 bits (176), Expect = 1e-12,   Method: Composition-based stats.
 Identities = 31/86 (36%), Positives = 46/86 (53%)
 Frame = -3

Query: 223 SEYSGDDCSELRCPTDCSSRGLCVDGECVCEEPYTGEDCRELRCPGDCSGKGQCANGTCL 282
           + ++G DC    C   C   G C +  CVC + +TG  C +L+C   C   G C+NG+C+
Sbjct: 263 TAFTGPDCETEVCRLVCV-HGHCRNQRCVCAQGWTGALCDQLQCDRRCHAHGFCSNGSCV 87

Query: 283 CQEGYAGEDCSQRRCLNACSGRGHCQ 308
           C +G+ G+ C+   C   CSG G C 
Sbjct: 86  CDKGWNGKHCTINGCPKDCSGHGECH 9

 Score = 63.5 bits (153), Expect = 6e-10,   Method: Composition-based stats.
 Identities = 23/58 (39%), Positives = 32/58 (55%)
 Frame = -3

Query: 188 CICNEGWFGKNCSEPYCPLGCSSRGVCVDGQCICDSEYSGDDCSELRCPTDCSSRGLC 245
           C+C +GW G  C +  C   C + G C +G C+CD  ++G  C+   CP DCS  G C
Sbjct: 185 CVCAQGWTGALCDQLQCDRRCHAHGFCSNGSCVCDKGWNGKHCTINGCPKDCSGHGEC 12

 Score = 33.1 bits (74), Expect = 0.87,   Method: Compositional matrix adjust.
 Identities = 16/44 (36%), Positives = 23/44 (52%), Gaps = 7/44 (15%)
 Frame = -1

Query: 238 DCSSRGLCVDGECVCEEPYTGEDCR-------ELRCPGDCSGKG 274
           +CS +G+C+ G+C C   + G DC         L C  +CSG G
Sbjct: 430 NCSGQGVCLHGQCRCFNGFKGSDCSLADKINVTLVCAKNCSGHG 299

 Score = 32.7 bits (73), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 18/44 (40%), Positives = 22/44 (50%), Gaps = 7/44 (15%)
 Frame = -1

Query: 269 DCSGKGQCANGTCLCQEGYAGEDCSQRR-------CLNACSGRG 305
           +CSG+G C +G C C  G+ G DCS          C   CSG G
Sbjct: 430 NCSGQGVCLHGQCRCFNGFKGSDCSLADKINVTLVCAKNCSGHG 299

 Score = 31.6 bits (70), Expect = 2.5,   Method: Compositional matrix adjust.
 Identities = 13/24 (54%), Positives = 16/24 (66%)
 Frame = -1

Query: 301 CSGRGHCQEGLCICEEGYQGPDCS 324
           CSG+G C  G C C  G++G DCS
Sbjct: 427 CSGQGVCLHGQCRCFNGFKGSDCS 356
>20469
          Length = 438

 Score = 72.0 bits (175), Expect = 1e-12,   Method: Composition-based stats.
 Identities = 53/150 (35%), Positives = 72/150 (48%), Gaps = 22/150 (14%)
 Frame = +2

Query: 1215 IHRITAQGRY---ELRVDM--RDGQEAVFAYYDKFAVEDSRSLYKIRIGSYNGTAGDSLS 1269
            +H +  + RY   ELR+++  + G +A +A+YD F V      + I +G+Y GTAGDSL+
Sbjct: 2    LHYLFYETRYVDFELRIELESQTGDKA-YAHYDHFKVHIK---FVITLGNYTGTAGDSLT 169

Query: 1270 YHQGRP---------------FSTEDRDNDVAVTNCAMSYKGAWWYKNCHRTNLNGKYGE 1314
              Q  P               FS +D D D    NCA  Y G WW+  C   NLNG +  
Sbjct: 170  PAQSLPGLNYPASDLNINNMKFSAKDYDLDKWEKNCAELYNG-WWHNACFAANLNGPFNT 346

Query: 1315 SRHSQGINWYHWKGHEFSIPFVEMKM--RP 1342
            S    G  WY W+  E   P  + KM  RP
Sbjct: 347  S----GFIWYTWQKWE---PLAKSKMLIRP 415
>29222
          Length = 484

 Score = 61.2 bits (147), Expect = 3e-09,   Method: Composition-based stats.
 Identities = 47/125 (37%), Positives = 56/125 (44%), Gaps = 18/125 (14%)
 Frame = +1

Query: 1239 AYYDKFAVEDSRSLYKIRIGSYNGTAGDSLSYHQ---------------GRPFSTEDRDN 1283
            A+YD+F   D  + Y I +G Y+GTAGDSL+  Q                  FS    DN
Sbjct: 34   AHYDRFHTSDIYN-YFITLGKYSGTAGDSLTPTQPLQGLDFPVSRLNINKMEFSVGVLDN 210

Query: 1284 DVAVT-NCAMSYKGAWWYKNCHRTNLNGKYGESRHSQGINWYHWKGHEFSIPFVEMKM-- 1340
            D     +CA  Y G WW+  C   NLNG Y  S    G  WY WK  E   P  + KM  
Sbjct: 211  DRWYQKSCAELYNG-WWHNACFAANLNGPYNTS----GFVWYTWKQWE---PLAKSKMMI 366

Query: 1341 RPYIH 1345
            RP  H
Sbjct: 367  RPVEH 381
>14044
          Length = 956

 Score = 55.1 bits (131), Expect = 2e-07,   Method: Composition-based stats.
 Identities = 38/103 (36%), Positives = 45/103 (43%), Gaps = 17/103 (16%)
 Frame = -2

Query: 1259 SYNGTAGDSLSYHQ---------------GRPFSTEDRDNDVAVTNCAMSYKGAWWYKNC 1303
            +Y GTAG+SL+  Q                  FS +D D D    NCA  Y G WW+  C
Sbjct: 955  NYTGTAGNSLTPTQPLEGLNFPVSALNINNMXFSAKDYDFDKWXKNCAELYNG-WWHNAC 779

Query: 1304 HRTNLNGKYGESRHSQGINWYHWKGHEFSIPFVEMKM--RPYI 1344
               NLNG Y  S    G  WY WK  E   P  + KM  RP +
Sbjct: 778  FAANLNGPYNTS----GFVWYTWKKWE---PLTKSKMMIRPVV 671
>13194
          Length = 549

 Score = 54.3 bits (129), Expect = 3e-07,   Method: Composition-based stats.
 Identities = 38/119 (31%), Positives = 50/119 (42%), Gaps = 3/119 (2%)
 Frame = -3

Query: 1111 AAQEATRSSLTSTVFTT---GGRVFSHPQDCAQHLMNGDTLSGVYTIFLNGELSHKLQVY 1167
            AAQ A R  +   V  T   G R      DC     +G +  G+Y I          QVY
Sbjct: 382  AAQSAGR--VARAVVQTPYWGDRCHIRIADCTDLYTSGTSRDGIYKIH-PARAPQAFQVY 212

Query: 1168 CDMTTDGGGWIVFQRRQNGQTDFFRKWADYRVGFGNLEDEFWLGLDNIHRITAQGRYEL 1226
            C +  D         R      F+R W +YR GFG+L  + WLGL  +H IT+   Y +
Sbjct: 211  CQIN-DRYQRTYLMLRDTKSFSFYRGWNEYRDGFGSLSGDHWLGLHKMHAITSSYMYRV 38
>37687
          Length = 402

 Score = 52.4 bits (124), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 38/100 (38%), Positives = 51/100 (51%), Gaps = 10/100 (10%)
 Frame = +3

Query: 1253 YKIRIGSYNGTAGDSLSYHQGRP-----FSTEDRDNDVAVT-NCAMS-YKGAWWYKNCHR 1305
            Y++ +  ++GTA D      G       FST DRDND+  T +CA + Y+G WWY NC  
Sbjct: 15   YRLTVEGFSGTAEDGFQTIIGTSSNQMQFSTYDRDNDIDYTVHCARNRYRGGWWYNNCGG 194

Query: 1306 TNLNGKYGESRHSQGINWYHWKGHE---FSIPFVEMKMRP 1342
            + LNG+Y  SR      +  W G      S   VEMK+ P
Sbjct: 195  SALNGEY-TSRTDGAWTYIIWHGMSRRMTSHSRVEMKIGP 311
>14608
          Length = 642

 Score = 50.4 bits (119), Expect = 5e-06,   Method: Composition-based stats.
 Identities = 38/125 (30%), Positives = 49/125 (39%), Gaps = 11/125 (8%)
 Frame = +1

Query: 154 QCNTNCCQESAATGQLDYVPHCSGHGNFSFESCGCICNEGWFGKNC----SEPYCPLG-- 207
           QCN   C+ S     L     C G  +   E   C C EGW G+ C        C     
Sbjct: 178 QCNNYICRRSGPEAAL-----CGGPSHGRCECGECDCLEGWKGEACDCSTDNSTCIASNG 342

Query: 208 --CSSRGVCVDGQCICDS--EYSGDDCSEL-RCPTDCSSRGLCVDGECVCEEPYTGEDCR 262
             C+ +G C  G+C C+   +Y G  C E   CP+ CS    C          YT E C+
Sbjct: 343 EICNDKGWCNCGRCKCNETLDYMGPTCEECPDCPSKCSQYRDCAQCRAFGTGKYTDEQCQ 522

Query: 263 ELRCP 267
           +  CP
Sbjct: 523 K-ECP 534

 Score = 40.4 bits (93), Expect = 0.005,   Method: Composition-based stats.
 Identities = 29/85 (34%), Positives = 33/85 (38%), Gaps = 2/85 (2%)
 Frame = +1

Query: 241 SRGLCVDGECVCEEPYTGEDCRELRCPGDCSGKGQCANGTCLCQEGYAGEDCSQRRCLNA 300
           S G C  GEC C E + GE C       DCS      N TC+   G              
Sbjct: 238 SHGRCECGECDCLEGWKGEAC-------DCSTD----NSTCIASNG------------EI 348

Query: 301 CSGRGHCQEGLCICEE--GYQGPDC 323
           C+ +G C  G C C E   Y GP C
Sbjct: 349 CNDKGWCNCGRCKCNETLDYMGPTC 423
>33896
          Length = 817

 Score = 41.6 bits (96), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 27/62 (43%), Positives = 31/62 (50%), Gaps = 3/62 (4%)
 Frame = +2

Query: 266 CPGDCSGKGQCANGTCLCQE-GYAGEDCS-QRRCLNACSGRGHCQEGLCICEEG-YQGPD 322
           C G   G+G+C  G C C E  Y G  C+  R C N   G G C EG+C C    Y GP 
Sbjct: 368 CSGMGCGEGRCRKGVCDCSETDYTGPACAVSRSCENVECGEGRCVEGVCDCTGTVYTGPT 547

Query: 323 CS 324
           CS
Sbjct: 548 CS 553
>19486
          Length = 445

 Score = 38.9 bits (89), Expect = 0.015,   Method: Composition-based stats.
 Identities = 16/30 (53%), Positives = 18/30 (60%)
 Frame = +3

Query: 1166 VYCDMTTDGGGWIVFQRRQNGQTDFFRKWA 1195
            VYCD       W V QRRQNG  +F+R WA
Sbjct: 366  VYCDKN-----WTVIQRRQNGSVNFYRGWA 440
>26257
          Length = 466

 Score = 38.1 bits (87), Expect = 0.021,   Method: Composition-based stats.
 Identities = 24/64 (37%), Positives = 30/64 (46%), Gaps = 6/64 (9%)
 Frame = -2

Query: 266 CPGDCSGKGQCAN-GTCLCQEGYAGEDCSQ--RRC---LNACSGRGHCQEGLCICEEGYQ 319
           C GDC   G+C    TC C+ GY G +C      C   L+AC G       +CI E G+ 
Sbjct: 429 CHGDCLNGGKCIGPNTCQCRHGYIGPNCELDIDECALGLSACRG-----NSVCINEPGWY 265

Query: 320 GPDC 323
             DC
Sbjct: 264 HCDC 253
>14158
          Length = 668

 Score = 36.2 bits (82), Expect = 0.093,   Method: Compositional matrix adjust.
 Identities = 55/169 (32%), Positives = 67/169 (39%), Gaps = 36/169 (21%)
 Frame = +3

Query: 188 CICNEGWFGKNCSEPYCPL---GCSSRGVCVDGQ-------CIC-DSEYSGDDCS---EL 233
           C+C  G+ G  C  PY       C++   C           C C DS YSGD C+   E 
Sbjct: 36  CVCPPGFNGTRCETPYNACDNNSCANNSTCTVNPDVSRGYVCDCADSNYSGDLCNINIEN 215

Query: 234 RCPTD--CSSRGLCVDG-----ECVCEEPYTGEDCR-------ELRCP-GDCSGKGQCAN 278
           +   D  C + G C D       C C   YTG  C        +L C  G C       N
Sbjct: 216 KSCADGLCQNPGSCTDDVNASFTCACAPGYTGSLCESPINYCVDLPCNNGTCQSNASLQN 395

Query: 279 GTCLCQEGYAGEDCSQR--RC-LNACSGRGHCQEGL----CICEEGYQG 320
            TC C EG+ G+ C      C  N C   G C +G+    CIC EGY G
Sbjct: 396 FTCECVEGFTGDVCDANIDDCQTNTCFYGGTCVDGIDHWSCICAEGYSG 542
>12576
          Length = 1682

 Score = 35.8 bits (81), Expect = 0.13,   Method: Compositional matrix adjust.
 Identities = 30/100 (30%), Positives = 43/100 (43%), Gaps = 11/100 (11%)
 Frame = -2

Query: 270  CSGKGQC-ANG---TCLCQEGYAGEDCSQRR--C-LNACSGRGHCQEG----LCICEEGY 318
            C   GQC  NG   TC C  G++G +C+ R   C  N C+  G C        C C  GY
Sbjct: 1645 CQNGGQCQPNGGSFTCSCVNGFSGVNCASRPNPCGSNPCANGGRCNANGASYTCSCSGGY 1466

Query: 319  QGPDCSAVAPPEDLRVAGISDRSIELEWDGPMAVTEYVIS 358
             G +C     P     A +   + E+E   P  V+  +++
Sbjct: 1465 YGFNCQTAPDPCSPTPAEMEVAATEMELPSPACVSADIMA 1346

 Score = 33.5 bits (75), Expect = 0.53,   Method: Compositional matrix adjust.
 Identities = 43/153 (28%), Positives = 63/153 (41%), Gaps = 36/153 (23%)
 Frame = -1

Query: 179  GNFSFESCGCICNEGWFGKNCS---EPYCPLGCSSRGVC--------VDGQCICDSEYSG 227
            G  +F+   C C+ G+ GK C+   +P     C + G C        +   C C + Y+G
Sbjct: 1139 GALTFK---CFCSAGYDGKTCTGLNDPCSSNPCRNGGRCSSVAQGGALTFSCXCINGYTG 969

Query: 228  DDCSELRCPTD---CSSRGLCVD--------GECVCEEPYTGEDCRELRCPGDCSGKGQC 276
             DCS+   P     C + G+C +          CVC   +TG  C +   P  CS +  C
Sbjct: 968  XDCSQTADPCSSKPCKNGGMCKNVVQNGALVAACVCAPGFTGATCSQENNP--CSSR-PC 798

Query: 277  ANGT--------------CLCQEGYAGEDCSQR 295
             NG               C C+ GY+GE C Q+
Sbjct: 797  KNGATCSPQLTRSSATFKCXCKSGYSGETCDQK 699

 Score = 33.1 bits (74), Expect = 0.73,   Method: Compositional matrix adjust.
 Identities = 54/169 (31%), Positives = 66/169 (39%), Gaps = 37/169 (21%)
 Frame = -1

Query: 198  NCSEPYCPLGCSSRGVC----VDGQCICDSEYSGDDCSELR--C-PTDCSSRGLC---VD 247
            +CS P  P  C + G C        C+C   Y+G  C+ L   C P  C + G+C   V 
Sbjct: 1448 DCSRPLQPNPCRNGGRCNRNGASFSCVCVGGYNGLTCASLSDPCNPNPCRNGGVCSTEVS 1269

Query: 248  G-----ECVCEEPYTGEDCRELR--C-PGDCSGKGQCANGT--------CLCQEGYAGED 291
            G     +C C   Y G  C+ L   C P  C   G C+           C C  GY G+ 
Sbjct: 1268 GGKLVSKCYCANGYEGNTCQTLADPCKPNPCKNGGLCSTTVVGGALTFKCFCSAGYDGKT 1089

Query: 292  CS--QRRCL-NACSGRGHC----QEGL----CICEEGYQGPDCSAVAPP 329
            C+     C  N C   G C    Q G     C C  GY G DCS  A P
Sbjct: 1088 CTGLNDPCSSNPCRNGGRCSSVAQGGALTFSCXCINGYTGXDCSQTADP 942
>19200
          Length = 436

 Score = 34.7 bits (78), Expect = 0.29,   Method: Compositional matrix adjust.
 Identities = 28/122 (22%), Positives = 55/122 (45%), Gaps = 8/122 (6%)
 Frame = -2

Query: 608 TSLDLEWDNSEAEAQEYKVVYSTLAGEQYHEVLVPKGIGPTTKTTLTDLVPGTEYGVGIS 667
           TS+++ WD+       YK+ Y+  A    + V      GP T   +++L P T Y V + 
Sbjct: 432 TSIEVSWDDPNFPVAGYKIFYNMFATPVMY-VWQQMETGPYTVADISNLEPHTVYAVRVQ 256

Query: 668 A------VMNSKQSIPATMNARTELDS-PRDLMVTASSETSISLIWTKASGP-IDHYRIT 719
           A        N  +++  ++N   E ++  R+  VT+     + L W+    P ++ Y + 
Sbjct: 255 AKSVDGRFGNLSETVTTSVNGDPERENVVRNFRVTSRLTNLVRLSWSPPKKPDVNVYMLK 76

Query: 720 FT 721
           ++
Sbjct: 75  YS 70
>09025
          Length = 1044

 Score = 33.5 bits (75), Expect = 0.67,   Method: Composition-based stats.
 Identities = 17/41 (41%), Positives = 20/41 (48%)
 Frame = -1

Query: 276 CANGTCLCQEGYAGEDCSQRRCLNACSGRGHCQEGLCICEE 316
           C +G C CQ G    DC    C   C G   CQ GLC C++
Sbjct: 945 CQSGLCDCQSGLC--DCQCGLCDCQC-GLCDCQSGLCYCQK 832

 Score = 30.0 bits (66), Expect = 7.2,   Method: Composition-based stats.
 Identities = 16/37 (43%), Positives = 17/37 (45%)
 Frame = -1

Query: 281 CLCQEGYAGEDCSQRRCLNACSGRGHCQEGLCICEEG 317
           C CQ G    DC    C   C G   CQ GLC C+ G
Sbjct: 951 CYCQSGLC--DCQSGLCDCQC-GLCDCQCGLCDCQSG 850
>26039
          Length = 441

 Score = 32.3 bits (72), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 22/60 (36%), Positives = 29/60 (48%), Gaps = 12/60 (20%)
 Frame = -1

Query: 247 DGECVCEEPYTGEDCRELRCPG----------DCSGKGQC--ANGTCLCQEGYAGEDCSQ 294
           +G C+C+  +TG  C E   PG           CS  G+C    G C+CQ GY G  C+Q
Sbjct: 378 NGRCICKPGWTGMRCSEHCRPGTFGAECKHNCSCSQHGECDPVTGACICQRGYRGTTCNQ 199

 Score = 30.0 bits (66), Expect = 6.0,   Method: Compositional matrix adjust.
 Identities = 23/58 (39%), Positives = 26/58 (44%), Gaps = 13/58 (22%)
 Frame = -1

Query: 188 CICNEGWFGKNCSEPYCPLG-----------CSSRGVC--VDGQCICDSEYSGDDCSE 232
           CIC  GW G  CSE +C  G           CS  G C  V G CIC   Y G  C++
Sbjct: 369 CICKPGWTGMRCSE-HCRPGTFGAECKHNCSCSQHGECDPVTGACICQRGYRGTTCNQ 199
>08926
          Length = 467

 Score = 32.3 bits (72), Expect = 1.3,   Method: Composition-based stats.
 Identities = 18/59 (30%), Positives = 29/59 (49%), Gaps = 3/59 (5%)
 Frame = +1

Query: 243 GLCV-DGECVCEEPYTGEDCRELRCPGDC--SGKGQCANGTCLCQEGYAGEDCSQRRCL 298
           G CV +G+C+C   + G  C   +C   C   G+ +     C C +G+ G  C +R C+
Sbjct: 7   GRCVANGKCLCPPSFYGRYCHRAKCNLTCLNGGRCRRRKNRCRCPKGFRGRRCERRSCV 183

 Score = 29.6 bits (65), Expect = 9.5,   Method: Composition-based stats.
 Identities = 19/53 (35%), Positives = 28/53 (52%), Gaps = 3/53 (5%)
 Frame = +1

Query: 274 GQC-ANGTCLCQEGYAGEDCSQRRCLNAC--SGRGHCQEGLCICEEGYQGPDC 323
           G+C ANG CLC   + G  C + +C   C   GR   ++  C C +G++G  C
Sbjct: 7   GRCVANGKCLCPPSFYGRYCHRAKCNLTCLNGGRCRRRKNRCRCPKGFRGRRC 165
>17679
          Length = 509

 Score = 31.6 bits (70), Expect = 2.4,   Method: Compositional matrix adjust.
 Identities = 23/76 (30%), Positives = 38/76 (50%), Gaps = 7/76 (9%)
 Frame = +3

Query: 688 SPRDLMVTASSETSISLIWTKASGP---IDHYRITFT--PSSGIS--SEVTVPRDRTSYT 740
           +PR++   A+S T+I + W++   P   I  YR+ +T  P   +    +  V  D    T
Sbjct: 135 APRNVRARAASSTTIVVSWSEPEIPNGIIQGYRVFYTRKPEEPVFFWEQQEVKNDNRLTT 314

Query: 741 LTDLEPGAEYIISITA 756
           ++ L+P   Y ISI A
Sbjct: 315 ISGLDPNQTYTISILA 362
>07945
          Length = 2023

 Score = 31.6 bits (70), Expect = 2.6,   Method: Compositional matrix adjust.
 Identities = 12/33 (36%), Positives = 18/33 (54%)
 Frame = -3

Query: 1043 PPDNLTASEVTRQSALISWQPPRAAIENYVLTY 1075
            PP    A+++T  S  +SWQPPR    + +  Y
Sbjct: 1700 PPSQPVATDITHNSLTLSWQPPRRNSSDTIYAY 1602
>38764
          Length = 1159

 Score = 31.2 bits (69), Expect = 3.1,   Method: Compositional matrix adjust.
 Identities = 23/70 (32%), Positives = 35/70 (50%), Gaps = 2/70 (2%)
 Frame = +3

Query: 899  RPTQVGRLDSSVVPNTVTEFAITRLYPATEYEISLN-SVRGR-EESERICTLVHTAMDSP 956
            RPT  GRL  S + + V +   +RL P +   ++ + SVR R ++ +  C+   TA   P
Sbjct: 936  RPTHCGRLPLSTLKSAVNDSWPSRLRPPSHLPLTTSRSVRRRTKKRQAACSASWTASTRP 1115

Query: 957  MDLIATNITP 966
            M   AT   P
Sbjct: 1116 MP*TATTPRP 1145
>15692
          Length = 673

 Score = 30.0 bits (66), Expect = 6.3,   Method: Composition-based stats.
 Identities = 27/97 (27%), Positives = 38/97 (39%), Gaps = 20/97 (20%)
 Frame = -2

Query: 228 DDCSELRCPTDCSSRG--LCVDGECVCEEPYTG----EDCRELRC----PGDCSGKGQC- 276
           D C ++  P +C+  G   C  G C C     G    + C +  C     GDC     C 
Sbjct: 561 DACKQI--PCECAQTGGCKCTGGICPCPTCNPGGNCTDACNQKPCGCIDAGDCQCGANCP 388

Query: 277 --------ANGTCLCQEGYAG-EDCSQRRCLNACSGR 304
                    +G C+C +G  G E C   +C+  CS R
Sbjct: 387 CLTCNPCKCSGACVCGQGCTGRESC---KCVRGCSCR 286

 Score = 30.0 bits (66), Expect = 6.5,   Method: Composition-based stats.
 Identities = 20/79 (25%), Positives = 30/79 (37%), Gaps = 19/79 (24%)
 Frame = -2

Query: 261 CRELRCPGDCSGKGQCANGTCLCQE----GYAGEDCSQRRCLNACSGRGHCQ-------- 308
           C+++ C    +G  +C  G C C      G   + C+Q+ C   C   G CQ        
Sbjct: 555 CKQIPCECAQTGGCKCTGGICPCPTCNPGGNCTDACNQKPC--GCIDAGDCQCGANCPCL 382

Query: 309 -------EGLCICEEGYQG 320
                   G C+C +G  G
Sbjct: 381 TCNPCKCSGACVCGQGCTG 325
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|18700014|ref|NP_570948.1| protocadherin 21 [Mus
musculus]
         (859 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

35151                                                                 142   8e-34
29507                                                                  93   5e-19
08409                                                                  87   3e-17
25641                                                                  84   3e-16
36752                                                                  82   7e-16
01558                                                                  77   4e-14
18971                                                                  76   5e-14
17709                                                                  73   4e-13
12240                                                                  55   2e-12
29160                                                                  70   3e-12
14946                                                                  70   3e-12
34098                                                                  48   4e-12
18709                                                                  66   6e-11
19661                                                                  61   2e-09
33294                                                                  60   3e-09
19334                                                                  58   1e-08
14391                                                                  58   2e-08
13573                                                                  57   3e-08
37203                                                                  55   9e-08
37991                                                                  55   2e-07
12703                                                                  54   3e-07
08534                                                                  53   5e-07
38442                                                                  47   2e-05
27585                                                                  47   3e-05
33084                                                                  44   3e-04
15121                                                                  41   0.002
14137                                                                  40   0.005
17610                                                                  39   0.012
38001                                                                  37   0.027
18019                                                                  35   0.16 
33808                                                                  34   0.20 
29111                                                                  31   1.7  
>35151
          Length = 844

 Score =  142 bits (357), Expect = 8e-34,   Method: Compositional matrix adjust.
 Identities = 97/294 (32%), Positives = 151/294 (51%), Gaps = 18/294 (6%)
 Frame = +2

Query: 316 VYELHVQVTEVNSPGSP---AAQATVPVTIRIVDLNNHPPTFYGESGPQNKFELSMFEHP 372
           VY + VQ TE++ PG        A+  VTI + D+N++ P          +F  + +   
Sbjct: 2   VYAMWVQATEIDVPGRQNFGTTTASAIVTISVTDVNDNVP----------EFSQTNYHAQ 151

Query: 373 PQGEILRGLKIT-------VNDSDQGANAKFNLRLVGPGG---IFRVVPQTVLNEAQVTI 422
            Q  +L+G+ +T       V+D DQG N+ F L +   G     F  +P+ V  E+ V +
Sbjct: 152 IQENMLKGVPLTFLGGVMRVSDKDQGTNSHFALTVEKNGQPYHDFTTLPEEVYTESTVLL 331

Query: 423 IVENSAAIDFEKSKLLTFKLLAIEVNTPEKFSSTADIVIQLLDTNDNVPKFTSHYYIARI 482
            V NS ++D+E  K + F+++A EV+T E+ SSTA + + +LD NDN P FT   Y+  +
Sbjct: 332 RVNNSESLDYEAEKEIIFQIVAREVDTAEQRSSTATVTLNILDMNDNAPNFTHSQYLFTV 511

Query: 483 PENAPGGSNVVAVTAVDPDTGPWGKVHYSIYGTGSDLFLIHPSTGLIYTQPWASLDAEGT 542
            E+A  G ++  + A D DTG +G V YSI G     F +    G +Y     +LD E T
Sbjct: 512 AEDASVGQSIGDIFASDDDTGSYGSVRYSIRGENRH-FRVDSLNGTMYVNN--ALDRETT 682

Query: 543 SRYNFYVKAEDMDGRYSLAEVFVTLLDVNDHYPQFVQS-----VQEKTMVLGTP 591
           SRY    +A D  G  +  E+ + + DVND+ P F +S     ++EK+     P
Sbjct: 683 SRYFLSAEAIDGGGTRAPTEIEIVVTDVNDNAPLFRRSDYEGVIREKSSTFLRP 844

 Score = 73.6 bits (179), Expect = 4e-13,   Method: Compositional matrix adjust.
 Identities = 50/140 (35%), Positives = 70/140 (50%), Gaps = 2/140 (1%)
 Frame = +2

Query: 121 VVILVTDANDEAPRFIQEPYIIRVPENIPAGSSIFKVQAEDKDTGSGGSVTYSL--QNLH 178
           V + + D ND AP F    Y+  V E+   G SI  + A D DTGS GSV YS+  +N H
Sbjct: 440 VTLNILDMNDNAPNFTHSQYLFTVAEDASVGQSIGDIFASDDDTGSYGSVRYSIRGENRH 619

Query: 179 SSKFSMDRHSGVLRLQAGATLDYEKSRAHYITVIAKDGGGRLRGADMVFSATTTVTINVE 238
              F +D  +G + +     LD E +  ++++  A DGGG          A T + I V 
Sbjct: 620 ---FRVDSLNGTMYVNNA--LDRETTSRYFLSAEAIDGGGT--------RAPTEIEIVVT 760

Query: 239 DVQDTAPIFVGTPYYGYVYE 258
           DV D AP+F  + Y G + E
Sbjct: 761 DVNDNAPLFRRSDYEGVIRE 820

 Score = 68.6 bits (166), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 64/254 (25%), Positives = 111/254 (43%), Gaps = 12/254 (4%)
 Frame = +2

Query: 113 GLNLVAEKVVILVTDANDEAPRFIQEPYIIRVPENIPAG------SSIFKVQAEDKDTGS 166
           G    +  V I VTD ND  P F Q  Y  ++ EN+  G        + +V  +D+ T S
Sbjct: 59  GTTTASAIVTISVTDVNDNVPEFSQTNYHAQIQENMLKGVPLTFLGGVMRVSDKDQGTNS 238

Query: 167 GGSVTYSLQNLHSSKFSM------DRHSGVLRLQAGATLDYEKSRAHYITVIAKDGGGRL 220
             ++T          F+          + +LR+    +LDYE  +     ++A++    +
Sbjct: 239 HFALTVEKNGQPYHDFTTLPEEVYTESTVLLRVNNSESLDYEAEKEIIFQIVARE----V 406

Query: 221 RGADMVFSATTTVTINVEDVQDTAPIFVGTPYYGYVYEDTLPGSEVLTVVAIDGDRGKPN 280
             A+   S+T TVT+N+ D+ D AP F  + Y   V ED   G  +  + A D D G   
Sbjct: 407 DTAEQR-SSTATVTLNILDMNDNAPNFTHSQYLFTVAEDASVGQSIGDIFASDDDTGSYG 583

Query: 281 HILYRLLNESDGIFEINETSGAISVLQSPALLRREVYELHVQVTEVNSPGSPAAQATVPV 340
            + Y +  E+   F ++  +G + V  + AL R       +    ++  G+   +A   +
Sbjct: 584 SVRYSIRGENRH-FRVDSLNGTMYV--NNALDRETTSRYFLSAEAIDGGGT---RAPTEI 745

Query: 341 TIRIVDLNNHPPTF 354
            I + D+N++ P F
Sbjct: 746 EIVVTDVNDNAPLF 787
>29507
          Length = 1143

 Score = 92.8 bits (229), Expect = 5e-19,   Method: Compositional matrix adjust.
 Identities = 103/366 (28%), Positives = 165/366 (45%), Gaps = 8/366 (2%)
 Frame = +2

Query: 155 FKVQAEDKDTGSGGSVTYSLQNLH--SSKFSMDRHSGVLRLQAGATLDYEKSRAHYITVI 212
            +VQA D+D+G  G + YS+ N    S  F +D  +GV+R+     LDYE      +T+ 
Sbjct: 2   IQVQATDRDSGPNGRIRYSIDNKTDPSGHFRIDPDTGVVRINR--PLDYETQSTFTLTLE 175

Query: 213 AKDGG-GRLRGADMVFSATTTVTI-NV-EDVQDTAPIFVGTP-YYGYVYEDTLPGSEVLT 268
           A D G  RL G     +A   VT+ N+ E   +   +F+ +P    ++ E+T  G+ V  
Sbjct: 176 ATDHGPTRLVG-----NAALEVTLENINEQPANIRLVFLQSPGREQHIMENTREGTLVAR 340

Query: 269 VVAIDGDRGKPNHILYRL-LNESDGIFEINETSGAISVLQSPALLRREVYELHVQVTEVN 327
           +   D D     H    + L   D IF +  + G++S++   +   RE    ++    V 
Sbjct: 341 ISIDDPDISADRHDDVDVNLFGGDDIFGLQVSEGSLSLVVVNSPPDRENKSSYLLTVTVT 520

Query: 328 SPGSPAAQATVPVTIRIVDLNNHPPTFYGESGPQNKFELSMFEHPPQGEILRGLKITVND 387
             G+P   A    TI I D N++ PTF G       +E  + E    G  +  +K+T +D
Sbjct: 521 DSGTPPLHARQSFTIYIDDENDNAPTFEG------SYEGEVPETADIGTFV--VKVTASD 676

Query: 388 SDQGANAKFNLRLVGPGGIFRVVPQTV-LNEAQVTIIVENSAAIDFEKSKLLTFKLLAIE 446
            D G NA+ +  +          PQ V       T ++     ID E +      ++A +
Sbjct: 677 RDAGDNARLSYSIESGSS-----PQAVWFAIDSKTGVITTQTPIDCEVNARPVLTVVARD 841

Query: 447 VNTPEKFSSTADIVIQLLDTNDNVPKFTSHYYIARIPENAPGGSNVVAVTAVDPDTGPWG 506
              P    ST+ +V+ + D ND  P+F + +Y AR+ E+A   S  V V A DP+ G   
Sbjct: 842 HGVPSLSGSTS-VVVTVRDVNDKQPEFDTSFYNARVAEDAAVLSCPVKVHATDPECGATS 1018

Query: 507 KVHYSI 512
            V Y +
Sbjct: 1019PVSYQL 1036

 Score = 86.7 bits (213), Expect = 4e-17,   Method: Compositional matrix adjust.
 Identities = 100/350 (28%), Positives = 155/350 (44%), Gaps = 15/350 (4%)
 Frame = +2

Query: 267 LTVVAIDGDRGKPNHILYRLLNESD--GIFEINETSGAISVLQSPALLRREVYELHVQVT 324
           + V A D D G    I Y + N++D  G F I+  +G + + +      +  + L ++ T
Sbjct: 2   IQVQATDRDSGPNGRIRYSIDNKTDPSGHFRIDPDTGVVRINRPLDYETQSTFTLTLEAT 181

Query: 325 EVNSPGSPAAQATVPVTIRIVDLNNHPPTFYGESGPQNKFELSMFEHPPQGEILRGLKIT 384
           + + P      A + VT+   ++N  P             E  + E+  +G ++   +I+
Sbjct: 182 D-HGPTRLVGNAALEVTLE--NINEQPANIRLVFLQSPGREQHIMENTREGTLV--ARIS 346

Query: 385 VNDSDQGANA--KFNLRLVGPGGIFRVVPQTVLNEAQVTIIVENSAAIDFEKSKLLTFKL 442
           ++D D  A+     ++ L G   IF +     ++E  ++++V NS      KS  L   +
Sbjct: 347 IDDPDISADRHDDVDVNLFGGDDIFGLQ----VSEGSLSLVVVNSPPDRENKSSYL-LTV 511

Query: 443 LAIEVNTPEKFSSTADIVIQLLDTNDNVPKFTSHYYIARIPENAPGGSNVVAVTAVDPDT 502
              +  TP    +     I + D NDN P F   Y    +PE A  G+ VV VTA D D 
Sbjct: 512 TVTDSGTP-PLHARQSFTIYIDDENDNAPTFEGSYE-GEVPETADIGTFVVKVTASDRDA 685

Query: 503 GPWGKVHYSIYGTGSD---LFLIHPSTGLIYTQPWASLDAEGTSRYNFYVKAEDMDGRYS 559
           G   ++ YSI    S     F I   TG+I TQ    +D E  +R    V A D  G  S
Sbjct: 686 GDNARLSYSIESGSSPQAVWFAIDSKTGVITTQ--TPIDCEVNARPVLTVVARDH-GVPS 856

Query: 560 LA---EVFVTLLDVNDHYPQFVQS-----VQEKTMVLGTPLKIEATDQDA 601
           L+    V VT+ DVND  P+F  S     V E   VL  P+K+ ATD + 
Sbjct: 857 LSGSTSVVVTVRDVNDKQPEFDTSFYNARVAEDAAVLSCPVKVHATDPEC 1006

 Score = 68.2 bits (165), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 53/174 (30%), Positives = 85/174 (48%), Gaps = 3/174 (1%)
 Frame = +2

Query: 119 EKVVILVTDANDEAPRFIQEPYIIRVPENIPAGSSIFKVQAEDKDTGSGGSVTYSLQNLH 178
           +   I + D ND AP F +  Y   VPE    G+ + KV A D+D G    ++YS+++  
Sbjct: 551 QSFTIYIDDENDNAPTF-EGSYEGEVPETADIGTFVVKVTASDRDAGDNARLSYSIESGS 727

Query: 179 SSK---FSMDRHSGVLRLQAGATLDYEKSRAHYITVIAKDGGGRLRGADMVFSATTTVTI 235
           S +   F++D  +GV+  Q    +D E +    +TV+A+D G          S +T+V +
Sbjct: 728 SPQAVWFAIDSKTGVITTQ--TPIDCEVNARPVLTVVARDHGV------PSLSGSTSVVV 883

Query: 236 NVEDVQDTAPIFVGTPYYGYVYEDTLPGSEVLTVVAIDGDRGKPNHILYRLLNE 289
            V DV D  P F  + Y   V ED    S  + V A D + G  + + Y+L+ +
Sbjct: 884 TVRDVNDKQPEFDTSFYNARVAEDAAVLSCPVKVHATDPECGATSPVSYQLVRQ 1045
>08409
          Length = 890

 Score = 86.7 bits (213), Expect = 3e-17,   Method: Compositional matrix adjust.
 Identities = 81/279 (29%), Positives = 133/279 (47%), Gaps = 12/279 (4%)
 Frame = +3

Query: 365 ELSMFEHPPQGEILRGLKITVNDSDQGANAKFNLRLVGPGGIFRVVPQTVLNEAQVTIIV 424
           ++++ E+ P+G  +   ++T +D D G N +   +          VPQT       +  +
Sbjct: 90  QINILENQPRGSHIG--EVTASDRDAGNNQRLQYQFS--------VPQTQFAINTYSGEI 239

Query: 425 ENSAAIDFEKSKLLTFKLLAIEVNTPEKFSSTADIVIQLLDTNDNVPKFTSHYYIARIPE 484
                +D E+ +L T  +   +   PE   ST  + I++LD NDN PKF    Y   + E
Sbjct: 240 STLGPLDREQQELYTLWVYVTDQGQPELSDSTV-VKIEVLDENDNRPKFMEDVYRRSVEE 416

Query: 485 NAPGGSNVVAVTAVDPDTGPWGKVHYSIY-GTGSDL---FLIHPSTGLIYTQPWASLDAE 540
           N P G +V+ V A D D G  G V +S +  + +D    F IH + G I T+    LD E
Sbjct: 417 NRPKGLHVLTVVAQDTDAGENGTVTFSFHRDSDADALTHFSIHAAKGWIITEE--VLDYE 590

Query: 541 GTSRYNFYVKAEDMDGRYSL---AEVFVTLLDVNDHYPQF----VQSVQEKTMVLGTPL- 592
             ++Y   V A D +G+  L   AEV + + D ND  P F    V     + + +GT + 
Sbjct: 591 TQTQYRLLVIAHD-NGQPRLSSSAEVLIDVADANDEAPLFHAREVTFYVVENVAIGTVVG 767

Query: 593 KIEATDQDAEEPNNLVDYSITRAEPVNVFDIDAHTGEIR 631
           +++A D+D+ E N  V Y +      ++F ++  TG I+
Sbjct: 768 EVKARDRDSGE-NGRVTYYLVGGNVFSLFSVNPATGMIQ 881

 Score = 60.5 bits (145), Expect(2) = 8e-14,   Method: Compositional matrix adjust.
 Identities = 65/209 (31%), Positives = 96/209 (45%), Gaps = 11/209 (5%)
 Frame = +3

Query: 482 IPENAPGGSNVVAVTAVDPDTGPWGKVHYSIYGTGSDLFLIHPSTGLIYTQPWASLDAEG 541
           I EN P GS++  VTA D D G   ++ Y  +      F I+  +G I T     LD E 
Sbjct: 99  ILENQPRGSHIGEVTASDRDAGNNQRLQYQ-FSVPQTQFAINTYSGEIST--LGPLDREQ 269

Query: 542 TSRYNFYVKAEDMDGRYSLAE---VFVTLLDVNDHYPQFVQSVQEKTMVLGTP-----LK 593
              Y  +V   D  G+  L++   V + +LD ND+ P+F++ V  +++    P     L 
Sbjct: 270 QELYTLWVYVTDQ-GQPELSDSTVVKIEVLDENDNRPKFMEDVYRRSVEENRPKGLHVLT 446

Query: 594 IEATDQDAEEPNNLVDYSITR---AEPVNVFDIDAHTGEIRLKNSIRSLEALHNITPSGD 650
           + A D DA E N  V +S  R   A+ +  F I A  G I  +      E L   T +  
Sbjct: 447 VVAQDTDAGE-NGTVTFSFHRDSDADALTHFSIHAAKGWIITE------EVLDYETQT-- 599

Query: 651 YSWSLQVQAKDRGSPSFSTTALLKIDITD 679
             + L V A D G P  S++A + ID+ D
Sbjct: 600 -QYRLLVIAHDNGQPRLSSSAEVLIDVAD 683

 Score = 35.4 bits (80), Expect(2) = 8e-14,   Method: Composition-based stats.
 Identities = 15/26 (57%), Positives = 20/26 (76%)
 Frame = +1

Query: 449 TPEKFSSTADIVIQLLDTNDNVPKFT 474
           TP   S+TADI I ++DTNDN P+F+
Sbjct: 1   TPHFLSATADIRIHIIDTNDNAPEFS 78

 Score = 71.2 bits (173), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 72/270 (26%), Positives = 115/270 (42%), Gaps = 4/270 (1%)
 Frame = +3

Query: 142 IRVPENIPAGSSIFKVQAEDKDTGSGGSVTYSLQNLHSSKFSMDRHSGVLRLQAGATLDY 201
           I + EN P GS I +V A D+D G+   + Y   ++  ++F+++ +SG   +     LD 
Sbjct: 93  INILENQPRGSHIGEVTASDRDAGNNQRLQYQF-SVPQTQFAINTYSG--EISTLGPLDR 263

Query: 202 EKSRAHYITVIAKDGGGRLRGADMVFSATTTVTINVEDVQDTAPIFVGTPYYGYVYEDTL 261
           E+   + + V   D G          S +T V I V D  D  P F+   Y   V E+  
Sbjct: 264 EQQELYTLWVYVTDQG------QPELSDSTVVKIEVLDENDNRPKFMEDVYRRSVEENRP 425

Query: 262 PGSEVLTVVAIDGDRGKPNHILYRLLNESDG----IFEINETSGAISVLQSPALLRREVY 317
            G  VLTVVA D D G+   + +    +SD      F I+   G I    +  +L  E  
Sbjct: 426 KGLHVLTVVAQDTDAGENGTVTFSFHRDSDADALTHFSIHAAKGWII---TEEVLDYETQ 596

Query: 318 ELHVQVTEVNSPGSPAAQATVPVTIRIVDLNNHPPTFYGESGPQNKFELSMFEHPPQGEI 377
             +  +   +  G P   ++  V I + D N+  P F+       +    + E+   G +
Sbjct: 597 TQYRLLVIAHDNGQPRLSSSAEVLIDVADANDEAPLFHAR-----EVTFYVVENVAIGTV 761

Query: 378 LRGLKITVNDSDQGANAKFNLRLVGPGGIF 407
           +  +K    D D G N +    LVG G +F
Sbjct: 762 VGEVK--ARDRDSGENGRVTYYLVG-GNVF 842

 Score = 50.1 bits (118), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 44/141 (31%), Positives = 60/141 (42%), Gaps = 9/141 (6%)
 Frame = +3

Query: 43  SLPEDTPVGSHVYTLNGTDPEGDP-----ISYHISFDPSTRSVFSVDPNFGNI----TLV 93
           S+ E+ P G HV T+   D +         S+H   D    + FS+    G I     L 
Sbjct: 405 SVEENRPKGLHVLTVVAQDTDAGENGTVTFSFHRDSDADALTHFSIHAAKGWIITEEVLD 584

Query: 94  XXXXXXXXXXXXXXXXXXXGLNLVAEKVVILVTDANDEAPRFIQEPYIIRVPENIPAGSS 153
                               L+  AE V+I V DANDEAP F        V EN+  G+ 
Sbjct: 585 YETQTQYRLLVIAHDNGQPRLSSSAE-VLIDVADANDEAPLFHAREVTFYVVENVAIGTV 761

Query: 154 IFKVQAEDKDTGSGGSVTYSL 174
           + +V+A D+D+G  G VTY L
Sbjct: 762 VGEVKARDRDSGENGRVTYYL 824
>25641
          Length = 921

 Score = 83.6 bits (205), Expect = 3e-16,   Method: Compositional matrix adjust.
 Identities = 73/259 (28%), Positives = 113/259 (43%), Gaps = 17/259 (6%)
 Frame = +2

Query: 113 GLNLVAEKVVILVTDANDEAPRFIQEPYII--RVPENIPAGSS----IFKVQAEDKDTGS 166
           G++  + +V + V DAND AP FI  PY I  R+ E   + ++    +  V A D+DT  
Sbjct: 146 GMHTASTRVQVTVLDANDNAPEFIDTPYRIENRIVEEDKSVTTRPKRLLTVLATDRDTDR 325

Query: 167 GGSVTYSLQNLHSSK----FSMDRHSGVLRLQAGATLDYEKSRAHY-ITVIAKDGGGRLR 221
             +++Y+LQ   +      F +D  +G L +      D    R++Y  TV+A+D   +  
Sbjct: 326 PNNISYTLQGYGTEPPNQYFRIDPITGGLFVIKPLDRDGPHGRSNYQFTVVARDEPHQPW 505

Query: 222 GADMVFSATTTVTINVEDVQDTAPIFVGTPYYGYVYEDTLPGSEVLTVVAIDGDRGKPNH 281
                     TV +   D+ D  P F  T   G V E + PG+ V+ V+A D DRG    
Sbjct: 506 QF-----GYATVEVLPADINDNKPTFDATKLKGSVDEHSEPGTSVMFVLATDPDRGNNGS 670

Query: 282 ILYRLLNES------DGIFEINETSGAISVLQSPALLRREVYELHVQVTEVNSPGSPAAQ 335
           ++Y ++  S         F I+  SG I        L RE           +  G P   
Sbjct: 671 VVYDIIKNSVTVGSKQDYFVIDRQSGLIKTNVDKRDLDRETIPSFTLEVRASDEGKPPLN 850

Query: 336 ATVPVTIRIVDLNNHPPTF 354
            T  +TI + D+N+  P F
Sbjct: 851 TTATITISLSDINDQKPVF 907

 Score = 64.7 bits (156), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 70/249 (28%), Positives = 111/249 (44%), Gaps = 23/249 (9%)
 Frame = +2

Query: 454 SSTADIVIQLLDTNDNVPKF--TSHYYIARIPENAPGGS----NVVAVTAVDPDTGPWGK 507
           +++  + + +LD NDN P+F  T +    RI E     +     ++ V A D DT     
Sbjct: 155 TASTRVQVTVLDANDNAPEFIDTPYRIENRIVEEDKSVTTRPKRLLTVLATDRDTDRPNN 334

Query: 508 VHYSIYGTGSD----LFLIHPSTG-LIYTQPWASLDAEGTSRYNFYVKAED---MDGRYS 559
           + Y++ G G++     F I P TG L   +P       G S Y F V A D      ++ 
Sbjct: 335 ISYTLQGYGTEPPNQYFRIDPITGGLFVIKPLDRDGPHGRSNYQFTVVARDEPHQPWQFG 514

Query: 560 LAEVFVTLLDVNDHYPQFVQ-----SVQEKTMVLGTPLKIEATDQDAEEPN----NLVDY 610
            A V V   D+ND+ P F       SV E +    + + + ATD D         +++  
Sbjct: 515 YATVEVLPADINDNKPTFDATKLKGSVDEHSEPGTSVMFVLATDPDRGNNGSVVYDIIKN 694

Query: 611 SITRAEPVNVFDIDAHTGEIRLKNSIRSLEALHNITPSGDYSWSLQVQAKDRGSPSFSTT 670
           S+T     + F ID  +G I+     R L+      PS    ++L+V+A D G P  +TT
Sbjct: 695 SVTVGSKQDYFVIDRQSGLIKTNVDKRDLD--RETIPS----FTLEVRASDEGKPPLNTT 856

Query: 671 ALLKIDITD 679
           A + I ++D
Sbjct: 857 ATITISLSD 883

 Score = 57.4 bits (137), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 81/301 (26%), Positives = 128/301 (42%), Gaps = 17/301 (5%)
 Frame = +2

Query: 294 FEINETSGAISVLQSPALLRREVYELHVQVTEVNSPGSPAAQATVPVTIRIVDLNNHPPT 353
           F I   +G + V ++   L  E Y+   ++T   S G   A   V VT+  +D N++ P 
Sbjct: 47  FGIKSATGGLFVAKT---LDYESYDRFFELTLNASDGMHTASTRVQVTV--LDANDNAPE 211

Query: 354 F----YGESGPQNKFELSMFEHPPQGEILRGLKITVNDSDQGANAKFNLRLVG---PGGI 406
           F    Y       + + S+   P +   L  +  T  D+D+  N  + L+  G   P   
Sbjct: 212 FIDTPYRIENRIVEEDKSVTTRPKR---LLTVLATDRDTDRPNNISYTLQGYGTEPPNQY 382

Query: 407 FRVVPQTVLNEAQVTIIVENSAAIDFEKSKLLTFKLLAIEVNTPEKFSSTADIVIQLLDT 466
           FR+ P T      + +I          +S      +   E + P +F   A + +   D 
Sbjct: 383 FRIDPIT----GGLFVIKPLDRDGPHGRSNYQFTVVARDEPHQPWQFGY-ATVEVLPADI 547

Query: 467 NDNVPKFTSHYYIARIPENAPGGSNVVAVTAVDPDTGPWGKVHYSI------YGTGSDLF 520
           NDN P F +      + E++  G++V+ V A DPD G  G V Y I       G+  D F
Sbjct: 548 NDNKPTFDATKLKGSVDEHSEPGTSVMFVLATDPDRGNNGSVVYDIIKNSVTVGSKQDYF 727

Query: 521 LIHPSTGLIYTQ-PWASLDAEGTSRYNFYVKAEDMDGRYSL---AEVFVTLLDVNDHYPQ 576
           +I   +GLI T      LD E    +   V+A D +G+  L   A + ++L D+ND  P 
Sbjct: 728 VIDRQSGLIKTNVDKRDLDRETIPSFTLEVRASD-EGKPPLNTTATITISLSDINDQKPV 904

Query: 577 F 577
           F
Sbjct: 905 F 907
>36752
          Length = 1243

 Score = 82.4 bits (202), Expect = 7e-16,   Method: Compositional matrix adjust.
 Identities = 63/201 (31%), Positives = 96/201 (47%), Gaps = 3/201 (1%)
 Frame = +3

Query: 157 VQAEDKDTGS--GGSVTYSLQNLHSSKFSMDRHSGVLRLQAGATLDYEKSRAHYITVIAK 214
           +QA D+D  S     +TY+L    +  F +++ SG+LR    A LD E  + +++ V A 
Sbjct: 9   IQASDRDEASTQNARITYTLDGQGADHFMLEKDSGILR--TAAALDRETQQRYHLEVTAT 182

Query: 215 DGGGRLRGADMVFSATTTVTINVEDVQDTAPIFVGTPYYGY-VYEDTLPGSEVLTVVAID 273
           DGGG         S  T V I + DV D  P F  +      V ED    + +  V  +D
Sbjct: 183 DGGG--------LSCVTEVQIFLRDVNDXPPEFTDSLRDTLTVQEDARVNTLLTRVTTVD 338

Query: 274 GDRGKPNHILYRLLNESDGIFEINETSGAISVLQSPALLRREVYELHVQVTEVNSPGSPA 333
            D G   +  Y L+     +F I   SG +S++ S  L R E  +  V +   N   SPA
Sbjct: 339 KDTGINRNTRYELMQREPSVFSIEPKSGILSLVGS--LDREEHPQYDVTIVAYNEI-SPA 509

Query: 334 AQATVPVTIRIVDLNNHPPTF 354
             AT  + + ++D+N++PPTF
Sbjct: 510 LSATTVLKVVVLDVNDNPPTF 572

 Score = 72.4 bits (176), Expect = 7e-13,   Method: Compositional matrix adjust.
 Identities = 51/181 (28%), Positives = 86/181 (47%), Gaps = 5/181 (2%)
 Frame = +1

Query: 186 RHSGVLRLQAGAT-----LDYEKSRAHYITVIAKDGGGRLRGADMVFSATTTVTINVEDV 240
           R S  L L+ G       LD+E SR +++T++A+D G          S T  ++IN+ D+
Sbjct: 706 RESLSLMLKNGEIKVSEPLDHEVSREYFLTILARDHGSP------PLSNTAIISINITDI 867

Query: 241 QDTAPIFVGTPYYGYVYEDTLPGSEVLTVVAIDGDRGKPNHILYRLLNESDGIFEINETS 300
            D  P F    Y   V E  L G+EV  V+A D D    + I Y ++ + + + ++++  
Sbjct: 868 NDNPPRFSQDTYATTVSEVVLVGTEVFKVMATDADSYANSVITYSII-DGNPVRQLSDWV 1044

Query: 301 GAISVLQSPALLRREVYELHVQVTEVNSPGSPAAQATVPVTIRIVDLNNHPPTFYGESGP 360
               ++Q    L RE  E +    +    G P   +T  V++R+ D N++PP F   + P
Sbjct: 1045LRDGIIQVAKHLDRESVERYALTIQARDSGQPMLYSTAVVSVRVEDANDNPPLFASNTTP 1224

Query: 361 Q 361
            
Sbjct: 1225H 1227

 Score = 64.7 bits (156), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 46/137 (33%), Positives = 70/137 (51%), Gaps = 5/137 (3%)
 Frame = +1

Query: 121 VVILVTDANDEAPRFIQEPYIIRVPENIPAGSSIFKVQAEDKDTGSGGSVTYSLQNLHSS 180
           + I +TD ND  PRF Q+ Y   V E +  G+ +FKV A D D+ +   +TYS+ + +  
Sbjct: 844 ISINITDINDNPPRFSQDTYATTVSEVVLVGTEVFKVMATDADSYANSVITYSIIDGNPV 1023

Query: 181 KFSMDRHSGVLR---LQAGATLDYEKSRAHYITVIAKDGGGRLRGADMVFSATTTVTINV 237
           +   D    VLR   +Q    LD E    + +T+ A+D      G  M++S T  V++ V
Sbjct: 1024RQLSD---WVLRDGIIQVAKHLDRESVERYALTIQARDS-----GQPMLYS-TAVVSVRV 1176

Query: 238 EDVQDTAPIFVG--TPY 252
           ED  D  P+F    TP+
Sbjct: 1177EDANDNPPLFASNTTPH 1227

 Score = 64.7 bits (156), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 52/180 (28%), Positives = 85/180 (47%), Gaps = 6/180 (3%)
 Frame = +3

Query: 506 GKVHYSIYGTGSDLFLIHPSTGLIYTQPWASLDAEGTSRYNFYVKAEDMDGRYSLAEVFV 565
            ++ Y++ G G+D F++   +G++ T   A+LD E   RY+  V A D  G   + EV +
Sbjct: 48  ARITYTLDGQGADHFMLEKDSGILRT--AAALDRETQQRYHLEVTATDGGGLSCVTEVQI 221

Query: 566 TLLDVNDHYPQFVQS------VQEKTMVLGTPLKIEATDQDAEEPNNLVDYSITRAEPVN 619
            L DVND  P+F  S      VQE   V     ++   D+D     N   Y + + EP +
Sbjct: 222 FLRDVNDXPPEFTDSLRDTLTVQEDARVNTLLTRVTTVDKDTGINRN-TRYELMQREP-S 395

Query: 620 VFDIDAHTGEIRLKNSIRSLEALHNITPSGDYSWSLQVQAKDRGSPSFSTTALLKIDITD 679
           VF I+  +G + L  S+   E            + + + A +  SP+ S T +LK+ + D
Sbjct: 396 VFSIEPKSGILSLVGSLDREEHPQ---------YDVTIVAYNEISPALSATTVLKVVVLD 548

 Score = 63.2 bits (152), Expect = 5e-10,   Method: Compositional matrix adjust.
 Identities = 57/175 (32%), Positives = 79/175 (45%), Gaps = 1/175 (0%)
 Frame = +3

Query: 113 GLNLVAEKVVILVTDANDEAPRFIQEPY-IIRVPENIPAGSSIFKVQAEDKDTGSGGSVT 171
           GL+ V E V I + D ND  P F       + V E+    + + +V   DKDTG   +  
Sbjct: 192 GLSCVTE-VQIFLRDVNDXPPEFTDSLRDTLTVQEDARVNTLLTRVTTVDKDTGINRNTR 368

Query: 172 YSLQNLHSSKFSMDRHSGVLRLQAGATLDYEKSRAHYITVIAKDGGGRLRGADMVFSATT 231
           Y L     S FS++  SG+L L    +LD E+   + +T++A +            SATT
Sbjct: 369 YELMQREPSVFSIEPKSGILSLVG--SLDREEHPQYDVTIVAYNE------ISPALSATT 524

Query: 232 TVTINVEDVQDTAPIFVGTPYYGYVYEDTLPGSEVLTVVAIDGDRGKPNHILYRL 286
            + + V DV D  P F  T YY  V ED   G+ V  V A   D G    I Y +
Sbjct: 525 VLKVVVLDVNDNPPTFERTSYYAAVAEDAGVGTVVGRVRATSLDIGANAAITYSI 689

 Score = 54.7 bits (130), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 53/162 (32%), Positives = 74/162 (45%), Gaps = 8/162 (4%)
 Frame = +1

Query: 424 VENSAAIDFEKSKLLTFKLLAIEVNTPEKFSSTADIVIQLLDTNDNVPKFTSHYYIARIP 483
           ++ S  +D E S+     +LA +  +P   S+TA I I + D NDN P+F+   Y   + 
Sbjct: 742 IKVSEPLDHEVSREYFLTILARDHGSP-PLSNTAIISINITDINDNPPRFSQDTYATTVS 918

Query: 484 ENAPGGSNVVAVTAVDPDTGPWGKVHYSIYGTG-----SDLFLIHPSTGLIYTQPWASLD 538
           E    G+ V  V A D D+     + YSI         SD  L     G+I  Q    LD
Sbjct: 919 EVVLVGTEVFKVMATDADSYANSVITYSIIDGNPVRQLSDWVL---RDGII--QVAKHLD 1083

Query: 539 AEGTSRYNFYVKAEDMDGR---YSLAEVFVTLLDVNDHYPQF 577
            E   RY   ++A D  G+   YS A V V + D ND+ P F
Sbjct: 1084RESVERYALTIQARD-SGQPMLYSTAVVSVRVEDANDNPPLF 1206

 Score = 49.7 bits (117), Expect = 6e-06,   Method: Compositional matrix adjust.
 Identities = 60/211 (28%), Positives = 91/211 (43%), Gaps = 8/211 (3%)
 Frame = +3

Query: 423 IVENSAAIDFEKSKLLTFKLLAIEVNTPEKFSSTADIVIQLLDTNDNVPKFT-SHYYIAR 481
           I+  +AA+D E  +    ++ A +       S   ++ I L D ND  P+FT S      
Sbjct: 114 ILRTAAALDRETQQRYHLEVTATDGG---GLSCVTEVQIFLRDVNDXPPEFTDSLRDTLT 284

Query: 482 IPENAPGGSNVVAVTAVDPDTGPWGKVHYSIYGTGSDLFLIHPSTGLIYTQPWASLDAEG 541
           + E+A   + +  VT VD DTG      Y +      +F I P +G++      SLD E 
Sbjct: 285 VQEDARVNTLLTRVTTVDKDTGINRNTRYELMQREPSVFSIEPKSGIL--SLVGSLDREE 458

Query: 542 TSRYNFYVKA-EDMDGRYSLAEVF-VTLLDVNDHYPQFVQS-----VQEKTMVLGTPLKI 594
             +Y+  + A  ++    S   V  V +LDVND+ P F ++     V E   V     ++
Sbjct: 459 HPQYDVTIVAYNEISPALSATTVLKVVVLDVNDNPPTFERTSYYAAVAEDAGVGTVVGRV 638

Query: 595 EATDQDAEEPNNLVDYSITRAEPVNVFDIDA 625
            AT  D    N  + YSI        F IDA
Sbjct: 639 RATSLDI-GANAAITYSIAAGNQQGKFVIDA 728

 Score = 44.7 bits (104), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 43/163 (26%), Positives = 73/163 (44%), Gaps = 3/163 (1%)
 Frame = +1

Query: 330 GSPAAQATVPVTIRIVDLNNHPPTFYGESGPQNKFELSMFEHPPQGEILRG---LKITVN 386
           GSP    T  ++I I D+N++PP F      Q+ +  ++ E      +L G    K+   
Sbjct: 814 GSPPLSNTAIISINITDINDNPPRF-----SQDTYATTVSE-----VVLVGTEVFKVMAT 963

Query: 387 DSDQGANAKFNLRLVGPGGIFRVVPQTVLNEAQVTIIVENSAAIDFEKSKLLTFKLLAIE 446
           D+D  AN+     ++  G   R +   VL +     I++ +  +D E  +     + A +
Sbjct: 964 DADSYANSVITYSIID-GNPVRQLSDWVLRDG----IIQVAKHLDRESVERYALTIQARD 1128

Query: 447 VNTPEKFSSTADIVIQLLDTNDNVPKFTSHYYIARIPENAPGG 489
              P  +S TA + +++ D NDN P F S+      P   PGG
Sbjct: 1129SGQPMLYS-TAVVSVRVEDANDNPPLFASN----TTPHQVPGG 1242

 Score = 43.5 bits (101), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 38/150 (25%), Positives = 70/150 (46%), Gaps = 7/150 (4%)
 Frame = +1

Query: 537 LDAEGTSRYNFYVKAEDMDG--RYSLAEVFVTLLDVNDHYPQFVQ-----SVQEKTMVLG 589
           LD E +  Y   + A D       + A + + + D+ND+ P+F Q     +V E  +V  
Sbjct: 760 LDHEVSREYFLTILARDHGSPPLSNTAIISINITDINDNPPRFSQDTYATTVSEVVLVGT 939

Query: 590 TPLKIEATDQDAEEPNNLVDYSITRAEPVNVFDIDAHTGEIRLKNSIRSLEALHNITPSG 649
              K+ ATD D+   N+++ YSI    PV          +  L++ I  ++   ++    
Sbjct: 940 EVFKVMATDADSYA-NSVITYSIIDGNPVR------QLSDWVLRDGI--IQVAKHLDRES 1092

Query: 650 DYSWSLQVQAKDRGSPSFSTTALLKIDITD 679
              ++L +QA+D G P   +TA++ + + D
Sbjct: 1093VERYALTIQARDSGQPMLYSTAVVSVRVED 1182
>01558
          Length = 2767

 Score = 76.6 bits (187), Expect = 4e-14,   Method: Compositional matrix adjust.
 Identities = 130/525 (24%), Positives = 231/525 (44%), Gaps = 21/525 (4%)
 Frame = +2

Query: 133 PRFIQEPYIIRVPENIPAGSSIFKVQAEDKDTGSGGSVTYSLQNLHS--SKFSMDRHSGV 190
           P F   PY++ VP      S++  VQA D D    G + Y L+      + FS++ +SG 
Sbjct: 62  PVFQNTPYVVPVPLTQAVNSTVISVQAFDPDL--RGQIQYRLEGFQPGITYFSLNENSGA 235

Query: 191 LRLQAGATLDYEKSRAHYITVIAKDGGGRLRGADMVFSATTTVTINVEDVQDTAPIFVGT 250
           + ++   T + +   ++ + V A+D G      D+V S   +V INV    + +P+F   
Sbjct: 236 ISVRRPLTGNSDVFASYTLLVTARDTG----NPDIVVSE--SVQINVLRNLN-SPVFGQQ 394

Query: 251 PYYGYVYEDTLPGSEVLTVVAIDGDRGKP-NHILYRLLN--ESDGIFEINETSGAISVLQ 307
            Y   VY+    GS V+ V A D D   P N + + + +   ++  F I+  +G I + +
Sbjct: 395 TYTQSVYDYESVGSSVVQVDATDSDITDPENQLTFEIESGATANEFFNIDPFTGIIRISK 574

Query: 308 SPALLRREVYELHVQVTEVNSPGSPAAQATVPVTIRIVDLNNHPPTFYGESGPQNKFELS 367
              L     Y   V   ++ +  S AA A+V VTI     N   P F          ++ 
Sbjct: 575 ELTLSTPSAYNFRVIARDLGA-LSRAATASVVVTIL---RNTGRPAFVNSPSA----DVI 730

Query: 368 MFEHPPQGEILRGLKITVNDSDQGANAKFNLRLVGP---GGIFRVVPQTVLNEAQVTIIV 424
           + E     + +  LK   +D D   N +    +V P      F++ P      A+V++  
Sbjct: 731 VSEAISVLDTIVTLKAVDSDPDTTPNGRVTYSIVSPIEARAFFQIDPVLGNITARVSL-- 904

Query: 425 ENSAAIDFEKSKLLTFKLLAIEVNTPEKFSSTADIVIQLLDTNDNVPKFTSHYYIARIPE 484
             +A +D  +   LT +  A +  TP +   ++++ + +    +  P F    Y+  +PE
Sbjct: 905 -TTAPVDVYR---LTVR--ASDQGTPTQ---SSEVTVTIRIRREGNPSFAQSEYVVTLPE 1057

Query: 485 NAPGGSNVVAVTAVDPDTGPWGKVHYSIYGTG--SDLFLIHPSTGLIYTQPWASLDAEGT 542
           + P  ++++ +TA DP      ++ Y I G G  S LF +   TGLI      SL ++  
Sbjct: 1058DTPLSTSIIKLTATDP---LARQLQYEITGDGMASTLFRLDVDTGLITLA--QSLRSDTA 1222

Query: 543 SRYNFYVKAEDMDGRYSLAEVFV-TLLDVNDHYPQFVQSVQEKTM----VLGTP-LKIEA 596
           + +   + A  ++     A   V  L+  N + P F+      T+     LG   LK+ A
Sbjct: 1223NSFVIRLVAFRVNDNSVXATTIVRVLVTRNANDPAFLHGDIAVTLSEDQALGVAFLKVNA 1402

Query: 597 TDQDAEEPNNLVDYSI--TRAEPVNV---FDIDAHTGEIRLKNSI 636
           TD D+ + N  + Y+I   ++EP  V   F I+  +G + + + +
Sbjct: 1403TDADSGD-NGAITYNIDGDKSEPTYVNQYFYINPTSGSLAVSSRL 1534

 Score = 72.0 bits (175), Expect = 1e-12,   Method: Compositional matrix adjust.
 Identities = 116/505 (22%), Positives = 202/505 (40%), Gaps = 44/505 (8%)
 Frame = +2

Query: 41   LFSLPEDTPVGSHVYTLNGTDPEGDPISYHISFDPSTRSVFSVDPNFGNITLVXXXXXXX 100
            + +LPEDTP+ + +  L  TDP    + Y I+ D    ++F +D + G ITL        
Sbjct: 1040 VVTLPEDTPLSTSIIKLTATDPLARQLQYEITGDGMASTLFRLDVDTGLITLAQSLRSDT 1219

Query: 101  XXXXXXXXXXXXGLNLVAEKV------------VILVTDANDEAPRFIQEPYIIRVPENI 148
                         + LVA +V            V++  +AND  P F+     + + E+ 
Sbjct: 1220 ANSFV--------IRLVAFRVNDNSVXATTIVRVLVTRNAND--PAFLHGDIAVTLSEDQ 1369

Query: 149  PAGSSIFKVQAEDKDTGSGGSVTYSLQNLHSSK------FSMDRHSGVLRLQAGATLDYE 202
              G +  KV A D D+G  G++TY++    S        F ++  SG L + +  + D  
Sbjct: 1370 ALGVAFLKVNATDADSGDNGAITYNIDGDKSEPTYVNQYFYINPTSGSLAVSSRLSDDTN 1549

Query: 203  KSRAHYITVIAKDGGGRLRGADMVFSATTTVTINVEDVQDTAPIFVGTPYYGYVYEDTLP 262
                + + V+A D G   R + +    T             +P+F  + Y   V E    
Sbjct: 1550 MPVLYVLYVVAIDNGVVRRSSFIRVRVTVVRNR-------NSPVFSQSLYNVTVDETIGV 1708

Query: 263  GSEVLTVVAIDGDRGKPNHILYRLLNE--SDGIFEINETSGAISVLQSPALLRREVYELH 320
               ++ V A D D  +   I Y +L+   +   F+++ TSG + +  S  LL+       
Sbjct: 1709 TQSLIRVTASDADGDR---ITYSMLSSIPASLYFDVDSTSGIVRIRNS--LLQDSTVTYT 1873

Query: 321  VQVTEVNSP---GSPA-AQATVPVTIRIVDLNNHPPTFYGESGPQNKFELSMFEHPPQGE 376
            + +  +++P    SP  A A V V +R    N + P F      Q+ + +++ E+ P   
Sbjct: 1874 MDIEALDAPVQGASPRNALAKVIVNVR---RNPNTPIF-----DQSVYNVTVSEYIPVRS 2029

Query: 377  ILRGLKITVNDSDQGANAKFNLRLVG---PGGIFRVVPQTVLNEAQVTIIVENSAAIDFE 433
            +++ +     D+    + +    +V    P   F V PQ      Q    + +    D  
Sbjct: 2030 VIQTVLARDADAASTPSGRLVYSIVSVSYPDPQFNVAPQ------QADFFIASPTTGDII 2191

Query: 434  KSKLLTFKLLAIEVNTPEKFSSTADIVIQLLDT-----------------NDNVPKFTSH 476
             ++ L+      +   P++F    DIVI+  D+                 N + P+FT  
Sbjct: 2192 LAQQLS------QARVPDRF----DIVIKAADSAIPPKSSQTLLSVNIIRNIHRPEFTEI 2341

Query: 477  YYIARIPENAPGGSNVVAVTAVDPD 501
             Y A I +    G  +  VTAVD D
Sbjct: 2342 RYGAAIEDTWAVGRTLFTVTAVDDD 2416

 Score = 61.6 bits (148), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 153/677 (22%), Positives = 260/677 (38%), Gaps = 56/677 (8%)
 Frame = +2

Query: 60   TDPEGDP---ISYHISFDPSTRSVFSVDPNFGNITL-VXXXXXXXXXXXXXXXXXXXGLN 115
            +DP+  P   ++Y I      R+ F +DP  GNIT  V                   G  
Sbjct: 785  SDPDTTPNGRVTYSIVSPIEARAFFQIDPVLGNITARVSLTTAPVDVYRLTVRASDQGTP 964

Query: 116  LVAEKVVILVTDANDEAPRFIQEPYIIRVPENIPAGSSIFKVQAED--------KDTGSG 167
              + +V + +    +  P F Q  Y++ +PE+ P  +SI K+ A D        + TG G
Sbjct: 965  TQSSEVTVTIRIRREGNPSFAQSEYVVTLPEDTPLSTSIIKLTATDPLARQLQYEITGDG 1144

Query: 168  GSVTYSLQNLHSSKFSMDRHSGVLRLQAGATLDYEKSRAHYITVIAKDGGGRLRGADMVF 227
                     + S+ F +D  +G++ L    +L  + + +  I ++A       R  D   
Sbjct: 1145 ---------MASTLFRLDVDTGLITL--AQSLRSDTANSFVIRLVA------FRVNDNSV 1273

Query: 228  SATTTVTINV-EDVQDTAPIFVGTPYYGYVYEDTLPGSEVLTVVAIDGDRGKPNHILYRL 286
             ATT V + V  +  D  P F+       + ED   G   L V A D D G    I Y +
Sbjct: 1274 XATTIVRVLVTRNAND--PAFLHGDIAVTLSEDQALGVAFLKVNATDADSGDNGAITYNI 1447

Query: 287  LNES------DGIFEINETSGAISV-------LQSPALLRREVYELHVQVTEVNSPGSPA 333
              +       +  F IN TSG+++V          P L     Y L+V   +        
Sbjct: 1448 DGDKSEPTYVNQYFYINPTSGSLAVSSRLSDDTNMPVL-----YVLYVVAID----NGVV 1600

Query: 334  AQATVPVTIRIVDLNNHPPTFYGESGPQNKFELSMFEHPPQGEILRGLKITVNDSDQGAN 393
             +++       V  N + P F      Q+ + +++ E     + L  +++T +D+D G  
Sbjct: 1601 RRSSFIRVRVTVVRNRNSPVF-----SQSLYNVTVDETIGVTQSL--IRVTASDAD-GDR 1756

Query: 394  AKFNLRLVGPGGIFRVVPQTVLNEAQVTIIVENSAAIDFEKSKLLTFKLLAIEVNTPEKF 453
              +++    P  ++  V  T        + + NS   D   +  +  + L   V      
Sbjct: 1757 ITYSMLSSIPASLYFDVDST-----SGIVRIRNSLLQDSTVTYTMDIEALDAPVQGASPR 1921

Query: 454  SSTADIVIQLLDTNDNVPKFTSHYYIARIPENAPGGSNVVAVTAVDPDTG--PWGKVHYS 511
            ++ A +++ +   N N P F    Y   + E  P  S +  V A D D    P G++ YS
Sbjct: 1922 NALAKVIVNVR-RNPNTPIFDQSVYNVTVSEYIPVRSVIQTVLARDADAASTPSGRLVYS 2098

Query: 512  IYGTG------------SDLFLIHPSTG-LIYTQPWASLDAEGTSRYNFYVKAED--MDG 556
            I                +D F+  P+TG +I  Q  +   A    R++  +KA D  +  
Sbjct: 2099 IVSVSYPDPQFNVAPQQADFFIASPTTGDIILAQQLSQ--ARVPDRFDIVIKAADSAIPP 2272

Query: 557  RYSLAEVFVTLLDVNDHYPQFVQ----SVQEKTMVLG-TPLKIEATDQDAEEP------N 605
            + S   + V ++  N H P+F +    +  E T  +G T   + A D D +E       N
Sbjct: 2273 KSSQTLLSVNIIR-NIHRPEFTEIRYGAAIEDTWAVGRTLFTVTAVDDDDKEQYNQNTNN 2449

Query: 606  NLVDYSITRAEPV--NVFDIDAHTGEIRLKNSIRSLEALHNITPSGDYSWSLQVQAKDRG 663
               DY I    P+    F +    G + ++N         N+      S+   + A DR 
Sbjct: 2450 AFFDYMIDENYPLAETYFGVTID-GVVYVRN---------NLLLDNSASYFFYIIAIDRS 2599

Query: 664  SPSFSTTALLKIDITDT 680
                S  A + I++T T
Sbjct: 2600 WQPLSNRAPVTINVTKT 2650

 Score = 51.6 bits (122), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 57/216 (26%), Positives = 99/216 (45%), Gaps = 9/216 (4%)
 Frame = +2

Query: 471 PKFTSHYYIARIPENAPGGSNVVAVTAVDPDTGPWGKVHYSIYG--TGSDLFLIHPSTGL 528
           P F +  Y+  +P      S V++V A DPD    G++ Y + G   G   F ++ ++G 
Sbjct: 62  PVFQNTPYVVPVPLTQAVNSTVISVQAFDPDL--RGQIQYRLEGFQPGITYFSLNENSGA 235

Query: 529 IYTQPWASLDAEGTSRYNFYVKAEDM---DGRYSLAEVFVTLLDVND---HYPQFVQSVQ 582
           I  +   + +++  + Y   V A D    D   S +     L ++N        + QSV 
Sbjct: 236 ISVRRPLTGNSDVFASYTLLVTARDTGNPDIVVSESVQINVLRNLNSPVFGQQTYTQSVY 415

Query: 583 EKTMVLGTPLKIEATDQDAEEPNNLVDYSITRAEPVN-VFDIDAHTGEIRLKNSIRSLEA 641
           +   V  + ++++ATD D  +P N + + I      N  F+ID  TG IR+       + 
Sbjct: 416 DYESVGSSVVQVDATDSDITDPENQLTFEIESGATANEFFNIDPFTGIIRIS------KE 577

Query: 642 LHNITPSGDYSWSLQVQAKDRGSPSFSTTALLKIDI 677
           L   TPS    ++ +V A+D G+ S + TA + + I
Sbjct: 578 LTLSTPSA---YNFRVIARDLGALSRAATASVVVTI 676
>18971
          Length = 787

 Score = 76.3 bits (186), Expect = 5e-14,   Method: Compositional matrix adjust.
 Identities = 54/143 (37%), Positives = 73/143 (51%), Gaps = 11/143 (7%)
 Frame = -2

Query: 121 VVILVTDANDEAPRFIQEPYIIRVPENIPAGSSIFKVQAEDKDTGSGGSVTYSLQNLHSS 180
           V++ V D ND +P F Q+ Y +RV EN   G+S+  V AED D+   G +TYSL   H  
Sbjct: 441 VILTVMDVNDISPSFKQDYYEVRVQENTAVGTSVGLVNAEDMDSNDNGRITYSLAWEHPQ 262

Query: 181 KF---SMDRH-------SGVLRLQAGATLDYEKSRAHYITVIAKDGGGRLRGADMVFSAT 230
           K     MD H        G L L+    LD+E +  + + V+A DGG   R      + T
Sbjct: 261 KMYFDPMDFHIPLFVSPEGTLTLE--RQLDHEMTSEYNLLVLAVDGGDPAR------TGT 106

Query: 231 TTVTINVEDVQDTAP-IFVGTPY 252
            T+T+ VEDV D  P I V  P+
Sbjct: 105 ATITLLVEDVNDNPPQIVVPEPH 37

 Score = 52.4 bits (124), Expect(2) = 1e-11,   Method: Compositional matrix adjust.
 Identities = 33/93 (35%), Positives = 42/93 (45%)
 Frame = -3

Query: 461 IQLLDTNDNVPKFTSHYYIARIPENAPGGSNVVAVTAVDPDTGPWGKVHYSIYGTGSDLF 520
           + ++D NDN P+F    Y   + EN   G  V  V A DPD G  GKV YSI     D+ 
Sbjct: 746 VNVMDENDNAPRFDQDVYYETVVENNDVGVQVARVRARDPDVGDNGKVDYSISSNRGDVG 567

Query: 521 LIHPSTGLIYTQPWASLDAEGTSRYNFYVKAED 553
           +     G I      S D E   + +F V A D
Sbjct: 566 VTMDRNGYIIA--TRSFDHEQNHQLSFEVFATD 474

 Score = 35.8 bits (81), Expect(2) = 1e-11,   Method: Compositional matrix adjust.
 Identities = 39/130 (30%), Positives = 61/130 (46%), Gaps = 7/130 (5%)
 Frame = -2

Query: 557 RYSLAEVFVTLLDVNDHYPQFVQS-----VQEKTMVLGTPLKIEATDQDAEEPNNLVDYS 611
           + S A V +T++DVND  P F Q      VQE T V  +   + A D D+ + N  + YS
Sbjct: 459 KRSTATVILTVMDVNDISPSFKQDYYEVRVQENTAVGTSVGLVNAEDMDSND-NGRITYS 283

Query: 612 ITRAEPVNV-FD-IDAHTGEIRLKNSIRSLEALHNITPSGDYSWSLQVQAKDRGSPSFST 669
           +    P  + FD +D H           +LE   +   + +Y  +L V A D G P+ + 
Sbjct: 282 LAWEHPQKMYFDPMDFHIPLFVSPEGTLTLERQLDHEMTSEY--NLLVLAVDGGDPARTG 109

Query: 670 TALLKIDITD 679
           TA + + + D
Sbjct: 108 TATITLLVED 79

 Score = 58.5 bits (140), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 46/137 (33%), Positives = 62/137 (45%), Gaps = 10/137 (7%)
 Frame = -2

Query: 452 KFSSTADIVIQLLDTNDNVPKFTSHYYIARIPENAPGGSNVVAVTAVDPDTGPWGKVHYS 511
           K  STA +++ ++D ND  P F   YY  R+ EN   G++V  V A D D+   G++ YS
Sbjct: 462 KKRSTATVILTVMDVNDISPSFKQDYYEVRVQENTAVGTSVGLVNAEDMDSNDNGRITYS 283

Query: 512 IYGTGSDLFLIHPSTGLI--YTQPWAS------LDAEGTSRYNFYVKAEDMDGRYSLAEV 563
           +           P    I  +  P  +      LD E TS YN  V A D          
Sbjct: 282 LAWEHPQKMYFDPMDFHIPLFVSPEGTLTLERQLDHEMTSEYNLLVLAVDGGDPARTGTA 103

Query: 564 FVTLL--DVNDHYPQFV 578
            +TLL  DVND+ PQ V
Sbjct: 102 TITLLVEDVNDNPPQIV 52

 Score = 42.4 bits (98), Expect = 9e-04,   Method: Compositional matrix adjust.
 Identities = 52/190 (27%), Positives = 70/190 (36%), Gaps = 17/190 (8%)
 Frame = -2

Query: 180 SKFSMDRHSGVLRL--QAGATLDYEKSRAHYITVIAKDGGG--------RLRGADMVFSA 229
           S+    R SG+L L  Q     D    R H+     +              R  D    +
Sbjct: 630 SRCGRQRESGLLHLVQQRRCRSDNGPQRVHHCHSFIRPRAEPPAIF*SLCHRQGDPKKRS 451

Query: 230 TTTVTINVEDVQDTAPIFVGTPYYGYVYEDTLPGSEVLTVVAIDGDRGKPNHILYRLLNE 289
           T TV + V DV D +P F    Y   V E+T  G+ V  V A D D      I Y L  E
Sbjct: 450 TATVILTVMDVNDISPSFKQDYYEVRVQENTAVGTSVGLVNAEDMDSNDNGRITYSLAWE 271

Query: 290 SDGIFEINETSGAISVLQSP-ALLRREVYELHVQVTEVN------SPGSPAAQATVPVTI 342
                  +     I +  SP   L  E    H   +E N        G PA   T  +T+
Sbjct: 270 HPQKMYFDPMDFHIPLFVSPEGTLTLERQLDHEMTSEYNLLVLAVDGGDPARTGTATITL 91

Query: 343 RIVDLNNHPP 352
            + D+N++PP
Sbjct: 90  LVEDVNDNPP 61

 Score = 32.7 bits (73), Expect = 0.61,   Method: Compositional matrix adjust.
 Identities = 33/149 (22%), Positives = 66/149 (44%), Gaps = 5/149 (3%)
 Frame = -2

Query: 330 GSPAAQATVPVTIRIVDLNNHPPTFYGESGPQNKFELSMFEHPPQGEILRGLKITVNDSD 389
           G P  ++T  V + ++D+N+  P+F      Q+ +E+ + E+   G  +  +     DS+
Sbjct: 471 GDPKKRSTATVILTVMDVNDISPSFK-----QDYYEVRVQENTAVGTSVGLVNAEDMDSN 307

Query: 390 QGANAKFNLRLVGPGGIF-----RVVPQTVLNEAQVTIIVENSAAIDFEKSKLLTFKLLA 444
                 ++L    P  ++       +P  V  E  +T+       +D E +      +LA
Sbjct: 306 DNGRITYSLAWEHPQKMYFDPMDFHIPLFVSPEGTLTL----ERQLDHEMTSEYNLLVLA 139

Query: 445 IEVNTPEKFSSTADIVIQLLDTNDNVPKF 473
           ++   P + + TA I + + D NDN P+ 
Sbjct: 138 VDGGDPAR-TGTATITLLVEDVNDNPPQI 55

 Score = 30.8 bits (68), Expect = 2.4,   Method: Compositional matrix adjust.
 Identities = 18/53 (33%), Positives = 29/53 (54%), Gaps = 4/53 (7%)
 Frame = -3

Query: 565 VTLLDVNDHYPQFVQSVQEKTMVLGTPLKIEATDQDAEEP----NNLVDYSIT 613
           V ++D ND+ P+F Q V  +T+V    + ++     A +P    N  VDYSI+
Sbjct: 746 VNVMDENDNAPRFDQDVYYETVVENNDVGVQVARVRARDPDVGDNGKVDYSIS 588
>17709
          Length = 812

 Score = 73.2 bits (178), Expect = 4e-13,   Method: Compositional matrix adjust.
 Identities = 54/175 (30%), Positives = 80/175 (45%)
 Frame = -3

Query: 184 MDRHSGVLRLQAGATLDYEKSRAHYITVIAKDGGGRLRGADMVFSATTTVTINVEDVQDT 243
           +DR++G  R+    TLD E   ++ I VIAKDGG          S+T T+ + V+D  D 
Sbjct: 681 VDRNTG--RVTTLQTLDREAVPSYSIKVIAKDGG------SPALSSTATILLTVKDRNDN 526

Query: 244 APIFVGTPYYGYVYEDTLPGSEVLTVVAIDGDRGKPNHILYRLLNESDGIFEINETSGAI 303
            P F    YY  V+E    G++V+ V A D D G    + YR +  +  IF I+  +G I
Sbjct: 525 MPQFHPDSYYVTVFETDAAGAKVVQVSASDKDAGSFGRVSYRFIGTTFSIFSIDSNTGVI 346

Query: 304 SVLQSPALLRREVYELHVQVTEVNSPGSPAAQATVPVTIRIVDLNNHPPTFYGES 358
           +         R  Y+L V     N   SP       VT+ +  L+   P F  ++
Sbjct: 345 TTTNVLRRASRSSYQLTV---GANDGRSPQLSVRASVTVIVARLDGTAPAFTSQT 190

 Score = 71.2 bits (173), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 63/208 (30%), Positives = 92/208 (44%), Gaps = 12/208 (5%)
 Frame = -3

Query: 430 IDFEKSKLLTFKLLAIEVNTPEKFSSTADIVIQLLDTNDNVPKFTSHYYIARIPENAPGG 489
           +D E     + K++A +  +P   SSTA I++ + D NDN+P+F    Y   + E    G
Sbjct: 642 LDREAVPSYSIKVIAKDGGSP-ALSSTATILLTVKDRNDNMPQFHPDSYYVTVFETDAAG 466

Query: 490 SNVVAVTAVDPDTGPWGKVHYSIYGTGSDLFLIHPSTGLIYTQPWASLDAEGTSRYNFYV 549
           + VV V+A D D G +G+V Y   GT   +F I  +TG+I T     L     S Y   V
Sbjct: 465 AKVVQVSASDKDAGSFGRVSYRFIGTTFSIFSIDSNTGVITTTNV--LRRASRSSYQLTV 292

Query: 550 KAEDMDGR----YSLAEVFVTLLDVNDHYPQFVQSVQEKTMVLGTPLKIEATD------- 598
            A   DGR       A V V +  ++   P F    Q K   +     ++A+        
Sbjct: 291 GAN--DGRSPQLSVRASVTVIVARLDGTAPAFTS--QTKVFEITEDFGVQASSLGQTVGQ 124

Query: 599 -QDAEEPNNLVDYSITRAEPVNVFDIDA 625
            Q      N + Y IT  +P  VF ID+
Sbjct: 123 VQATGGVGNTITYFITDGDPFQVFAIDS 40

 Score = 57.8 bits (138), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 60/191 (31%), Positives = 90/191 (47%), Gaps = 7/191 (3%)
 Frame = -3

Query: 121 VVILVTDANDEAPRFIQEPYIIRVPENIPAGSSIFKVQAEDKDTGSGGSVTYSLQNLHSS 180
           +++ V D ND  P+F  + Y + V E   AG+ + +V A DKD GS G V+Y       S
Sbjct: 558 ILLTVKDRNDNMPQFHPDSYYVTVFETDAAGAKVVQVSASDKDAGSFGRVSYRFIGTTFS 379

Query: 181 KFSMDRHSGVLRLQAGATLDYEKSRAHY-ITVIAKDGGGRLRGADMVFSATTTVTINVED 239
            FS+D ++GV+       +    SR+ Y +TV A DG    R   +  S   +VT+ V  
Sbjct: 378 IFSIDSNTGVITT---TNVLRRASRSSYQLTVGANDG----RSPQL--SVRASVTVIVAR 226

Query: 240 VQDTAPIFVGTPYYGYVYEDTLPGSEVL--TVVAIDGDRGKPNHILYRLLNESDG----I 293
           +  TAP F        + ED    +  L  TV  +    G  N I Y +   +DG    +
Sbjct: 225 LDGTAPAFTSQTKVFEITEDFGVQASSLGQTVGQVQATGGVGNTITYFI---TDGDPFQV 55

Query: 294 FEINETSGAIS 304
           F I ++SG I+
Sbjct: 54  FAI-DSSGVIT 25

 Score = 30.0 bits (66), Expect = 3.6,   Method: Compositional matrix adjust.
 Identities = 13/28 (46%), Positives = 21/28 (75%)
 Frame = -3

Query: 652 SWSLQVQAKDRGSPSFSTTALLKIDITD 679
           S+S++V AKD GSP+ S+TA + + + D
Sbjct: 621 SYSIKVIAKDGGSPALSSTATILLTVKD 538
>12240
          Length = 977

 Score = 46.2 bits (108), Expect(2) = 2e-12,   Method: Compositional matrix adjust.
 Identities = 40/134 (29%), Positives = 66/134 (49%), Gaps = 8/134 (5%)
 Frame = +2

Query: 536 SLDAEGTSRYNFYVKAEDMD-GRYSL---AEVFVTLLDVNDHYPQFVQSVQEKTMVLGTP 591
           +LD E  S++NF V+  D    R S    A V V + D+ND  P+F QS     +VL T 
Sbjct: 509 ALDHEAKSQFNFTVQVHDRGVPRLSASAPAPVVVYITDINDTPPRFTQSSYTAKVVLPTY 688

Query: 592 LKIEATDQDAEEPNNL----VDYSITRAEPVNVFDIDAHTGEIRLKNSIRSLEALHNITP 647
             +     +AE+P+ +    + YSI      +VF I+  +G + ++++    + + N   
Sbjct: 689 HDVRVVKVEAEDPDTISTKPLTYSIAGGNEGSVFAINPQSGVLHVEHT----DHIQN--- 847

Query: 648 SGDYSWSLQVQAKD 661
               S+ L+VQA D
Sbjct: 848 ----SYELKVQASD 877

 Score = 45.1 bits (105), Expect(2) = 2e-12,   Method: Compositional matrix adjust.
 Identities = 23/83 (27%), Positives = 43/83 (51%)
 Frame = +1

Query: 423 IVENSAAIDFEKSKLLTFKLLAIEVNTPEKFSSTADIVIQLLDTNDNVPKFTSHYYIARI 482
           +V  + AID+E        +LA  + +    ++   +++ + D NDN P+FT+  +   +
Sbjct: 163 VVSTTRAIDYEHHHFFNLTILAANIVSA---TAVTHMLVHVGDENDNRPQFTAQAFFGNV 333

Query: 483 PENAPGGSNVVAVTAVDPDTGPW 505
            E+A  GS V     ++PD+ PW
Sbjct: 334 SESAEAGSMV-----LNPDSLPW 387

 Score = 54.7 bits (130), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 42/145 (28%), Positives = 70/145 (48%), Gaps = 3/145 (2%)
 Frame = +2

Query: 426 NSAAIDFEKSKLLTFKLLAIEVNTPE-KFSSTADIVIQLLDTNDNVPKFTSHYYIARIPE 484
           N  A+D E      F +   +   P    S+ A +V+ + D ND  P+FT   Y A++  
Sbjct: 500 NLIALDHEAKSQFNFTVQVHDRGVPRLSASAPAPVVVYITDINDTPPRFTQSSYTAKVVL 679

Query: 485 NAPGGSNVVAVTAVDPDTGPWGKVHYSIYGTGS-DLFLIHPSTGLIYTQPWASLDAEGTS 543
                  VV V A DPDT     + YSI G     +F I+P +G+++ +    +      
Sbjct: 680 PTYHDVRVVKVEAEDPDTISTKPLTYSIAGGNEGSVFAINPQSGVLHVEHTDHI------ 841

Query: 544 RYNFYVKAEDMDGRY-SLAEVFVTL 567
           + ++ +K +  DGRY +L +VF+T+
Sbjct: 842 QNSYELKVQASDGRYDTLVDVFITV 916

 Score = 47.4 bits (111), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 29/75 (38%), Positives = 42/75 (56%), Gaps = 1/75 (1%)
 Frame = +2

Query: 121 VVILVTDANDEAPRFIQEPYIIRVPENIPAGSSIFKVQAEDKDTGSGGSVTYSLQNLHS- 179
           VV+ +TD ND  PRF Q  Y  +V         + KV+AED DT S   +TYS+   +  
Sbjct: 602 VVVYITDINDTPPRFTQSSYTAKVVLPTYHDVRVVKVEAEDPDTISTKPLTYSIAGGNEG 781

Query: 180 SKFSMDRHSGVLRLQ 194
           S F+++  SGVL ++
Sbjct: 782 SVFAINPQSGVLHVE 826

 Score = 42.7 bits (99), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 34/127 (26%), Positives = 60/127 (47%), Gaps = 9/127 (7%)
 Frame = +1

Query: 471 PKFTSHYYIARIPENAPGGSNVVAVTAVDPDTGPWGKVHYSIYGTGSDLFLIHPSTGLIY 530
           PKF S   +  + EN+P G+ + AV A    T     V+  I G   D F ++ ++G++ 
Sbjct: 4   PKFPSSEIVTELKENSPAGTVLDAVRAESQST----IVYTIIAGNTDDCFFLNXNSGVVS 171

Query: 531 TQPWASLDAEGTSRYNFYVKAEDMDGRYSLAEVFVTLLDVNDHYPQFV---------QSV 581
           T    ++D E    +N  + A ++    ++  + V + D ND+ PQF          +S 
Sbjct: 172 TT--RAIDYEHHHFFNLTILAANIVSATAVTHMLVHVGDENDNRPQFTAQAFFGNVSESA 345

Query: 582 QEKTMVL 588
           +  +MVL
Sbjct: 346 EAGSMVL 366

 Score = 42.0 bits (97), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 37/138 (26%), Positives = 64/138 (46%), Gaps = 3/138 (2%)
 Frame = +1

Query: 133 PRFIQEPYIIRVPENIPAGSSIFKVQAEDKDTGSGGSVTYSLQNLHSSK-FSMDRHSGVL 191
           P+F     +  + EN PAG+ +  V+AE + T     + Y++   ++   F ++ +SGV+
Sbjct: 4   PKFPSSEIVTELKENSPAGTVLDAVRAESQST-----IVYTIIAGNTDDCFFLNXNSGVV 168

Query: 192 RLQAGATLDYEKSRAHYITVIAKDGGGRLRGADMVFSAT--TTVTINVEDVQDTAPIFVG 249
                  +DYE      +T++A +          + SAT  T + ++V D  D  P F  
Sbjct: 169 STTRA--IDYEHHHFFNLTILAAN----------IVSATAVTHMLVHVGDENDNRPQFTA 312

Query: 250 TPYYGYVYEDTLPGSEVL 267
             ++G V E    GS VL
Sbjct: 313 QAFFGNVSESAEAGSMVL 366

 Score = 33.9 bits (76), Expect = 0.30,   Method: Compositional matrix adjust.
 Identities = 30/115 (26%), Positives = 51/115 (44%), Gaps = 4/115 (3%)
 Frame = +2

Query: 325 EVNSPGSP--AAQATVPVTIRIVDLNNHPPTFYGESGPQNKFELSMFEHPPQGEILRGLK 382
           +V+  G P  +A A  PV + I D+N+ PP F  +S    K  L      P    +R +K
Sbjct: 551 QVHDRGVPRLSASAPAPVVVYITDINDTPPRF-TQSSYTAKVVL------PTYHDVRVVK 709

Query: 383 ITVNDSDQGANAKFNLRLVG--PGGIFRVVPQTVLNEAQVTIIVENSAAIDFEKS 435
           +   D D  +       + G   G +F + PQ+ +   + T  ++NS  +  + S
Sbjct: 710 VEAEDPDTISTKPLTYSIAGGNEGSVFAINPQSGVLHVEHTDHIQNSYELKVQAS 874
>29160
          Length = 1022

 Score = 70.1 bits (170), Expect = 3e-12,   Method: Compositional matrix adjust.
 Identities = 53/173 (30%), Positives = 83/173 (47%), Gaps = 7/173 (4%)
 Frame = -2

Query: 421 TIIVENSAAIDFEKSKLLTFKLLAIEVNTPEKFSSTADIVIQLLDTNDNVPKFTSHYYIA 480
           +I+V N   +D+E++    F L  I  +   + ++TA + I + D NDN P         
Sbjct: 976 SILVYNE--VDYEQASRQFFNLTVIAEDPNPRHTATAYVAIXVRDFNDNAPAIKPQVITV 803

Query: 481 RIPENAPGGSNVVAVTAVDPDTGPWGKVHYSI--YGTGSDLFLIHPSTGLIYTQPWASLD 538
           RI E+ P G +V    A D D+G   K  +SI  +      F IHP TG +  +    LD
Sbjct: 802 RIFEDEPAGFHVATFNATDMDSGDNAKFEFSIDRHTDPRRHFSIHPETGRVTLR--RPLD 629

Query: 539 AEGTSRYNFYVKAED-----MDGRYSLAEVFVTLLDVNDHYPQFVQSVQEKTM 586
            E    +   ++A D     M G Y    VFV   D+ND++PQF+++ Q + +
Sbjct: 628 RETQDHHVITIRAIDKGDPPMTG-YGTLTVFVK--DINDNFPQFLENYQPQVL 479

 Score = 52.8 bits (125), Expect = 7e-07,   Method: Compositional matrix adjust.
 Identities = 37/128 (28%), Positives = 54/128 (42%)
 Frame = -2

Query: 121 VVILVTDANDEAPRFIQEPYIIRVPENIPAGSSIFKVQAEDKDTGSGGSVTYSLQNLHSS 180
           V I V D ND AP    +   +R+ E+ PAG  +    A D D+G      +S+      
Sbjct: 868 VAIXVRDFNDNAPAIKPQVITVRIFEDEPAGFHVATFNATDMDSGDNAKFEFSIDRHTDP 689

Query: 181 KFSMDRHSGVLRLQAGATLDYEKSRAHYITVIAKDGGGRLRGADMVFSATTTVTINVEDV 240
           +     H    R+     LD E    H IT+ A D G      D   +   T+T+ V+D+
Sbjct: 688 RRHFSIHPETGRVTLRRPLDRETQDHHVITIRAIDKG------DPPMTGYGTLTVFVKDI 527

Query: 241 QDTAPIFV 248
            D  P F+
Sbjct: 526 NDNFPQFL 503

 Score = 48.5 bits (114), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 47/167 (28%), Positives = 71/167 (42%), Gaps = 4/167 (2%)
 Frame = -2

Query: 199 LDYEKSRAHY--ITVIAKDGGGRLRGADMVFSATTTVTINVEDVQDTAPIFVGTPYYGYV 256
           +DYE++   +  +TVIA+D   R        +AT  V I V D  D AP          +
Sbjct: 955 VDYEQASRQFFNLTVIAEDPNPR-------HTATAYVAIXVRDFNDNAPAIKPQVITVRI 797

Query: 257 YEDTLPGSEVLTVVAIDGDRGKPNHILYRLLNESDGI--FEINETSGAISVLQSPALLRR 314
           +ED   G  V T  A D D G      + +   +D    F I+  +G ++ L+ P  L R
Sbjct: 796 FEDEPAGFHVATFNATDMDSGDNAKFEFSIDRHTDPRRHFSIHPETGRVT-LRRP--LDR 626

Query: 315 EVYELHVQVTEVNSPGSPAAQATVPVTIRIVDLNNHPPTFYGESGPQ 361
           E  + HV        G P       +T+ + D+N++ P F     PQ
Sbjct: 625 ETQDHHVITIRAIDKGDPPMTGYGTLTVFVKDINDNFPQFLENYQPQ 485

 Score = 38.1 bits (87), Expect = 0.015,   Method: Compositional matrix adjust.
 Identities = 21/77 (27%), Positives = 37/77 (48%)
 Frame = -1

Query: 185 DRHSGVLRLQAGATLDYEKSRAHYITVIAKDGGGRLRGADMVFSATTTVTINVEDVQDTA 244
           DR +G+  +    + D EK + +YI ++  D  G  + +    + T T+T+ + DV D  
Sbjct: 299 DRGNGIATISTLRSFDREKQKYYYIPIVMWDMRG--KNSKQAMTGTNTLTVTIADVNDNV 126

Query: 245 PIFVGTPYYGYVYEDTL 261
           P       + Y Y+D L
Sbjct: 125 PKSGHQDMFVYNYKDLL 75
>14946
          Length = 1599

 Score = 70.1 bits (170), Expect = 3e-12,   Method: Compositional matrix adjust.
 Identities = 111/433 (25%), Positives = 176/433 (40%), Gaps = 14/433 (3%)
 Frame = -3

Query: 133  PRFIQEPYIIRVPENIPAGSSIFKVQAEDKD-TGSGGSVTYSLQNLHSS--KFSMDRHSG 189
            PR     Y + V E+   G    +V A D D T     VTY+L     +   F +   SG
Sbjct: 1591 PRLNPTIYSVGVSEDRVVGDPFLQVTALDADFTAPNNLVTYTLAGNSKALEYFQVGSSSG 1412

Query: 190  VLRLQAGATLDYEKSRAHYITVIAKDGGGRLRGADMVFSATTTVTINVEDVQDTAPIFVG 249
             L +     LD ++++ + +T+ A+D G   R A    +AT TV +N     +  P F+ 
Sbjct: 1411 QLSVLQPLYLDQDRTQTYQLTITARDLGFPSRAATN--TATVTVAVNR---NNNPPFFIN 1247

Query: 250  TPYYGYVYEDTLPGSEVLTVVAIDGDRGKP-NHILYRLLNESDGIFEINETSGAISVLQS 308
            TPY   +      G+ V+ V   D D   P N +  +++ +       +  +  I  + +
Sbjct: 1246 TPYDVTISTPAASGTSVIPVTVTDADSVAPFNTVSLQVIGDDSAPIYFSLGNDRIIRVSN 1067

Query: 309  PALLRREV---YELHVQVTEVNSPGSPAAQATVPVTIRIVDLNNHPPTFYGESGPQNKFE 365
             + L  +    Y + +  T+   P S  A ATV +T+R    N   P F       N   
Sbjct: 1066 VSNLNTDTATFYRMRLLATDFGYP-SRTATATVGITVR---RNLFSPQFTNT----NTIR 911

Query: 366  LSMFEHPPQGEILRGLKITVNDSDQGANAKFNLRLVGPG---GIFRVVPQTVLNEAQVTI 422
            +++ E    G  +  L  T +D+D   N +F   LVG G     F + P     + ++T+
Sbjct: 910  VTIPETAAIGTFITDLNATDSDTD-APNNEFQFSLVGVGDSVNFFFINPL----DGRITL 746

Query: 423  I--VENSAAIDFEKSKLLTFKLLAIEVNTPEKFSSTADIVIQLLDTNDNVPKFTSHYYIA 480
            +  VEN+    ++       ++   +   P+ FS T   V  + DT   V  FT   Y  
Sbjct: 745  LNSVENTVNSGYQ------LRVRVTDGGNPQLFSETLVEVTVVRDTETLV--FTLPRYTV 590

Query: 481  RIPENAPGGSNVVAVTAVDPDTGPWGKVHYSI--YGTGSDLFLIHPSTGLIYTQPWASLD 538
             I EN      V +V A      P   V Y +  Y  G D F I  STG I+ +     D
Sbjct: 589  DISENLAENRIVTSVVA-----QPQDSVTYRLTGYSDGPDYFNISSSTGSIFIKTDLRSD 425

Query: 539  AEGTSRYNFYVKA 551
                + Y   V+A
Sbjct: 424  KNRKTSYLLGVEA 386

 Score = 61.6 bits (148), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 67/266 (25%), Positives = 122/266 (45%), Gaps = 12/266 (4%)
 Frame = -3

Query: 430  IDFEKSKLLTFKLLAIEVNTPEKFSSTADIVIQLLDTNDNVPKFTSHYYIARIPENAPGG 489
            +D ++++     + A ++  P + ++    V   ++ N+N P F +  Y   I   A  G
Sbjct: 1384 LDQDRTQTYQLTITARDLGFPSRAATNTATVTVAVNRNNNPPFFINTPYDVTISTPAASG 1205

Query: 490  SNVVAVTAVDPDT-GPWGKVHYSIYGTGSD-LFLIHPSTGLIYTQPWASLDAEGTSRYNF 547
            ++V+ VT  D D+  P+  V   + G  S  ++    +  +I     ++L+ +  + Y  
Sbjct: 1204 TSVIPVTVTDADSVAPFNTVSLQVIGDDSAPIYFSLGNDRIIRVSNVSNLNTDTATFYRM 1025

Query: 548  YVKAEDMD--GRYSLAEVFVTLLDVNDHYPQF-----VQSVQEKTMVLGTPL-KIEATDQ 599
             + A D     R + A V +T+   N   PQF     ++    +T  +GT +  + ATD 
Sbjct: 1024 RLLATDFGYPSRTATATVGITVRR-NLFSPQFTNTNTIRVTIPETAAIGTFITDLNATDS 848

Query: 600  DAEEPNNLVDYSITR-AEPVNVFDIDAHTGEIRLKNSIRSLEALHNITPSGDYSWSLQVQ 658
            D + PNN   +S+    + VN F I+   G I L NS+       N   SG   + L+V+
Sbjct: 847  DTDAPNNEFQFSLVGVGDSVNFFFINPLDGRITLLNSV------ENTVNSG---YQLRVR 695

Query: 659  AKDRGSPSFSTTALLKIDIT-DTERL 683
              D G+P   +  L+++ +  DTE L
Sbjct: 694  VTDGGNPQLFSETLVEVTVVRDTETL 617

 Score = 48.9 bits (115), Expect = 8e-06,   Method: Compositional matrix adjust.
 Identities = 44/119 (36%), Positives = 60/119 (50%), Gaps = 4/119 (3%)
 Frame = -1

Query: 454 SSTADIVIQLLDTNDNVPKFTSHYYIARIPENAPGGSNVVAVTAVDPDTGPWGKVHYSIY 513
           ++TAD+ I +   NDN P F+   Y A I E    GS+VV + A D DT     + YS+ 
Sbjct: 360 TATADVEISVR-RNDNPPIFSRQIYPAVISEYTALGSSVVQLVASDADTQ--DVLKYSLL 190

Query: 514 GTG--SDLFLIHPSTGLIYTQPWASLDAEGTSRYNFYVKAEDMDG--RYSLAEVFVTLL 568
            +   +D F + PSTGLI  +    L  +  SRY F V+  D     R   A V VT+L
Sbjct: 189 TSSGVTDYFYLGPSTGLISLR--TLLLGQQASRYTFDVQVSDQSDPERTDTATVDVTIL 19
>34098
          Length = 1349

 Score = 48.1 bits (113), Expect(2) = 4e-12,   Method: Compositional matrix adjust.
 Identities = 34/96 (35%), Positives = 46/96 (47%), Gaps = 1/96 (1%)
 Frame = +1

Query: 165  GSGGSVTYSL-QNLHSSKFSMDRHSGVLRLQAGATLDYEKSRAHYITVIAKDGGGRLRGA 223
            G    VTY L  +  + +F +D   G   L  G  LDYE  + + + V+A+DGG      
Sbjct: 1063 GENARVTYDLLSDWATDRFQLDSVLGTFTLIGG--LDYELRQLYTLRVVARDGGSP---- 1224

Query: 224  DMVFSATTTVTINVEDVQDTAPIFVGTPYYGYVYED 259
                S TTTV +NV DV D  P F    Y   +YE+
Sbjct: 1225 --PMSTTTTVYMNVVDVNDNQPEFDPASYTQLLYEN 1326

 Score = 41.6 bits (96), Expect(2) = 4e-12,   Method: Compositional matrix adjust.
 Identities = 19/53 (35%), Positives = 31/53 (58%)
 Frame = +3

Query: 113 GLNLVAEKVVILVTDANDEAPRFIQEPYIIRVPENIPAGSSIFKVQAEDKDTG 165
           G++  +  V I ++D+ND  PRF Q+ Y   V E+   G+++ +V A D D G
Sbjct: 906 GVHTTSASVTIAISDSNDNRPRFTQDFYSFDVHEDTDRGATVARVTALDADMG 1064

 Score = 45.1 bits (105), Expect(2) = 7e-08,   Method: Compositional matrix adjust.
 Identities = 42/144 (29%), Positives = 60/144 (41%)
 Frame = +3

Query: 134 RFIQEPYIIRVPENIPAGSSIFKVQAEDKDTGSGGSVTYSLQNLHSSKFSMDRHSGVLRL 193
           RF    Y +  P + PA     +    D DT   G V   L+     KF + ++ G + +
Sbjct: 672 RFSPSVYNVSYPSSRPATPPWSRSGGPDPDTT--GQVQLRLRGRGDDKFDI-QNDGTI-V 839

Query: 194 QAGATLDYEKSRAHYITVIAKDGGGRLRGADMVFSATTTVTINVEDVQDTAPIFVGTPYY 253
                LD E    + + V A DG         V + + +VTI + D  D  P F    Y 
Sbjct: 840 AVALPLDRESEDRYTLIVTADDG---------VHTTSASVTIAISDSNDNRPRFTQDFYS 992

Query: 254 GYVYEDTLPGSEVLTVVAIDGDRG 277
             V+EDT  G+ V  V A+D D G
Sbjct: 993 FDVHEDTDRGATVARVTALDADMG 1064

 Score = 30.4 bits (67), Expect(2) = 7e-08,   Method: Compositional matrix adjust.
 Identities = 23/90 (25%), Positives = 43/90 (47%), Gaps = 1/90 (1%)
 Frame = +1

Query: 277  GKPNHILYRLLNE-SDGIFEINETSGAISVLQSPALLRREVYELHVQVTEVNSPGSPAAQ 335
            G+   + Y LL++ +   F+++   G  +++       R++Y L V   +    GSP   
Sbjct: 1063 GENARVTYDLLSDWATDRFQLDSVLGTFTLIGGLDYELRQLYTLRVVARD---GGSPPMS 1233

Query: 336  ATVPVTIRIVDLNNHPPTFYGESGPQNKFE 365
             T  V + +VD+N++ P F   S  Q  +E
Sbjct: 1234 TTTTVYMNVVDVNDNQPEFDPASYTQLLYE 1323

 Score = 41.6 bits (96), Expect(2) = 1e-04,   Method: Compositional matrix adjust.
 Identities = 19/50 (38%), Positives = 31/50 (62%)
 Frame = +3

Query: 454 SSTADIVIQLLDTNDNVPKFTSHYYIARIPENAPGGSNVVAVTAVDPDTG 503
           +++A + I + D+NDN P+FT  +Y   + E+   G+ V  VTA+D D G
Sbjct: 915 TTSASVTIAISDSNDNRPRFTQDFYSFDVHEDTDRGATVARVTALDADMG 1064

 Score = 22.7 bits (47), Expect(2) = 1e-04,   Method: Compositional matrix adjust.
 Identities = 14/43 (32%), Positives = 21/43 (48%), Gaps = 2/43 (4%)
 Frame = +1

Query: 537  LDAEGTSRYNFYVKAEDMDG--RYSLAEVFVTLLDVNDHYPQF 577
            LD E    Y   V A D       +   V++ ++DVND+ P+F
Sbjct: 1162 LDYELRQLYTLRVVARDGGSPPMSTTTTVYMNVVDVNDNQPEF 1290

 Score = 40.8 bits (94), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 39/135 (28%), Positives = 55/135 (40%), Gaps = 6/135 (4%)
 Frame = +3

Query: 472 KFTSHYYIARIPENAPGGSNVVAVTAVDPDTGPWGKVHYSIYGTGSDLFLIHPSTGLIYT 531
           +F+   Y    P + P           DPDT   G+V   + G G D F I     ++  
Sbjct: 672 RFSPSVYNVSYPSSRPATPPWSRSGGPDPDTT--GQVQLRLRGRGDDKFDIQNDGTIVAV 845

Query: 532 QPWASLDAEGTSRYNFYVKAEDMDGRYSL-AEVFVTLLDVNDHYPQFVQ-----SVQEKT 585
                LD E   RY   V A+D  G ++  A V + + D ND+ P+F Q      V E T
Sbjct: 846 A--LPLDRESEDRYTLIVTADD--GVHTTSASVTIAISDSNDNRPRFTQDFYSFDVHEDT 1013

Query: 586 MVLGTPLKIEATDQD 600
               T  ++ A D D
Sbjct: 1014DRGATVARVTALDAD 1058

 Score = 35.4 bits (80), Expect = 0.087,   Method: Compositional matrix adjust.
 Identities = 26/95 (27%), Positives = 45/95 (47%)
 Frame = +1

Query: 391  GANAKFNLRLVGPGGIFRVVPQTVLNEAQVTIIVENSAAIDFEKSKLLTFKLLAIEVNTP 450
            G NA+    L+      R    +VL     T+I      +D+E  +L T +++A +  +P
Sbjct: 1063 GENARVTYDLLSDWATDRFQLDSVL--GTFTLI----GGLDYELRQLYTLRVVARDGGSP 1224

Query: 451  EKFSSTADIVIQLLDTNDNVPKFTSHYYIARIPEN 485
               S+T  + + ++D NDN P+F    Y   + EN
Sbjct: 1225 -PMSTTTTVYMNVVDVNDNQPEFDPASYTQLLYEN 1326
>18709
          Length = 501

 Score = 65.9 bits (159), Expect = 6e-11,   Method: Compositional matrix adjust.
 Identities = 52/155 (33%), Positives = 80/155 (51%), Gaps = 3/155 (1%)
 Frame = +2

Query: 153 SIFKVQAEDKDTGSGGSVTYSLQNLHSSKFSMDRHSGVLRLQAGATLDYEKSRAHY-ITV 211
           SIF+V A D D G+ G++TYSL     S F++D  +G LR  A    D E +R+HY + V
Sbjct: 5   SIFQVLAMDPDMGNNGNITYSLLENPESAFAIDPVTGTLR--AMKKFDRE-NRSHYRVMV 175

Query: 212 IAKDGGGRLRGADMVFSATTTVTINVEDVQDTAPIFVGTPYYGYVYEDTLPGSEVLTVVA 271
            AKD G          ++  T+ +N+ DV D+   F  + +  YV E+   G+ V  +  
Sbjct: 176 QAKDRGT------PSMTSIATIHVNISDVNDSPTHFAQSHFNFYVEEERPRGTIVDILRV 337

Query: 272 IDGDRGKPNHILYRLLNE--SDGIFEINETSGAIS 304
           +D D    N + Y  L+E  +   F I+ +SG I+
Sbjct: 338 VDLDEKTSNQLQYSFLSEFAAPSQFSIDVSSGRIT 442

 Score = 49.7 bits (117), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 44/147 (29%), Positives = 63/147 (42%), Gaps = 7/147 (4%)
 Frame = +2

Query: 491 NVVAVTAVDPDTGPWGKVHYSIYGTGSDLFLIHPSTGLIYTQPWASLDAEGTSRYNFYVK 550
           ++  V A+DPD G  G + YS+       F I P TG +  +     D E  S Y   V+
Sbjct: 5   SIFQVLAMDPDMGNNGNITYSLLENPESAFAIDPVTGTL--RAMKKFDRENRSHYRVMVQ 178

Query: 551 AEDMD--GRYSLAEVFVTLLDVNDHYPQFVQS----VQEKTMVLGTPLKI-EATDQDAEE 603
           A+D       S+A + V + DVND    F QS      E+    GT + I    D D + 
Sbjct: 179 AKDRGTPSMTSIATIHVNISDVNDSPTHFAQSHFNFYVEEERPRGTIVDILRVVDLDEKT 358

Query: 604 PNNLVDYSITRAEPVNVFDIDAHTGEI 630
            N L    ++     + F ID  +G I
Sbjct: 359 SNQLQYSFLSEFAAPSQFSIDVSSGRI 439

 Score = 47.0 bits (110), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 30/118 (25%), Positives = 55/118 (46%)
 Frame = +2

Query: 266 VLTVVAIDGDRGKPNHILYRLLNESDGIFEINETSGAISVLQSPALLRREVYELHVQVTE 325
           +  V+A+D D G   +I Y LL   +  F I+  +G +  ++      R  Y + VQ  +
Sbjct: 8   IFQVLAMDPDMGNNGNITYSLLENPESAFAIDPVTGTLRAMKKFDRENRSHYRVMVQAKD 187

Query: 326 VNSPGSPAAQATVPVTIRIVDLNNHPPTFYGESGPQNKFELSMFEHPPQGEILRGLKI 383
               G+P+  +   + + I D+N+ P  F      Q+ F   + E  P+G I+  L++
Sbjct: 188 ---RGTPSMTSIATIHVNISDVNDSPTHF-----AQSHFNFYVEEERPRGTIVDILRV 337

 Score = 37.0 bits (84), Expect = 0.035,   Method: Compositional matrix adjust.
 Identities = 26/88 (29%), Positives = 42/88 (47%)
 Frame = +2

Query: 592 LKIEATDQDAEEPNNLVDYSITRAEPVNVFDIDAHTGEIRLKNSIRSLEALHNITPSGDY 651
            ++ A D D     N+  YS+    P + F ID  TG +R         A+         
Sbjct: 11  FQVLAMDPDMGNNGNIT-YSLLE-NPESAFAIDPVTGTLR---------AMKKFDRENRS 157

Query: 652 SWSLQVQAKDRGSPSFSTTALLKIDITD 679
            + + VQAKDRG+PS ++ A + ++I+D
Sbjct: 158 HYRVMVQAKDRGTPSMTSIATIHVNISD 241
>19661
          Length = 684

 Score = 60.8 bits (146), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 61/214 (28%), Positives = 95/214 (44%), Gaps = 13/214 (6%)
 Frame = +1

Query: 430 IDFEKSKLLTFKLLAIEVNTPEKFSSTADIVIQLLDTNDNVPKFTSHYYIARIPENAPGG 489
           +D E  +     L A +V++         +++Q  D NDN P F S  Y   + E A  G
Sbjct: 58  LDRESQERYQLVLRASDVSSASYADMHLTVILQ--DVNDNSPVFESLRYTHTVSEVARVG 231

Query: 490 SNVVAVTAVDPDTGPWGKVHYSIYGTGSDL-----FLIHPSTG-LIYTQPWASLDAEGTS 543
           ++++ V A D D      +HYS+    +D      F +H  TG ++  +P   LD E  +
Sbjct: 232 TSILQVAARDXDBAANSLIHYSLAPLSADSADTQPFFVHSETGTIVLHRP---LDHEAQA 402

Query: 544 RYNFYVKAED--MDGRYSLAEVFVTLLDVNDHYPQFVQ-----SVQEKTMVLGTPLKIEA 596
            Y F   A D  M  R + A V + +LD+ND+ P F Q      + ++        K+  
Sbjct: 403 DYTFLAVATDSGMPARSATALVHIIVLDLNDNXPHFTQLSFNCYITDQAHRGQLVTKVTG 582

Query: 597 TDQDAEEPNNLVDYSITRAEPVNVFDIDAHTGEI 630
            D D  +  NLV YSI        F I++ +G I
Sbjct: 583 MDADDSDKGNLV-YSIIGGNEKQAFTINSASGLI 681

 Score = 49.3 bits (116), Expect = 6e-06,   Method: Compositional matrix adjust.
 Identities = 60/217 (27%), Positives = 101/217 (46%), Gaps = 1/217 (0%)
 Frame = +1

Query: 314 REVYELHVQVTEVNSPGSPAAQATVPVTIRIVDLNNHPPTFYGESGPQNKFELSMFEHPP 373
           +E Y+L ++ ++V+S    A+ A + +T+ + D+N++ P F        ++  ++ E   
Sbjct: 73  QERYQLVLRASDVSS----ASYADMHLTVILQDVNDNSPVF-----ESLRYTHTVSEVAR 225

Query: 374 QGEILRGLKITVNDSDQGANAKFNLRLVGPGGIFRVVPQTVLNEAQVTIIVENSAAIDFE 433
            G  +  L++   D D  AN+  +  L  P        Q     ++   IV +   +D E
Sbjct: 226 VGTSI--LQVAARDXDBAANSLIHYSL-APLSADSADTQPFFVHSETGTIVLHR-PLDHE 393

Query: 434 KSKLLTFKLLAIEVNTPEKFSSTADIVIQLLDTNDNVPKFTSHYYIARIPENAPGGSNVV 493
                TF  +A +   P + S+TA + I +LD NDN P FT   +   I + A  G  V 
Sbjct: 394 AQADYTFLAVATDSGMPAR-SATALVHIIVLDLNDNXPHFTQLSFNCYITDQAHRGQLVT 570

Query: 494 AVTAVDPDTGPWGKVHYSIYGTGS-DLFLIHPSTGLI 529
            VT +D D    G + YSI G      F I+ ++GLI
Sbjct: 571 KVTGMDADDSDKGNLVYSIIGGNEKQAFTINSASGLI 681

 Score = 33.9 bits (76), Expect = 0.32,   Method: Compositional matrix adjust.
 Identities = 17/54 (31%), Positives = 25/54 (46%)
 Frame = +1

Query: 121 VVILVTDANDEAPRFIQEPYIIRVPENIPAGSSIFKVQAEDKDTGSGGSVTYSL 174
           V I+V D ND  P F Q  +   + +    G  + KV   D D    G++ YS+
Sbjct: 466 VHIIVLDLNDNXPHFTQLSFNCYITDQAHRGQLVTKVTGMDADDSDKGNLVYSI 627
>33294
          Length = 816

 Score = 60.5 bits (145), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 56/178 (31%), Positives = 87/178 (48%), Gaps = 4/178 (2%)
 Frame = -2

Query: 117 VAEKVVILVTDANDEAPRFIQEPYIIRVPENIPAGSSIFKVQAEDKDTGSGGSVTYSLQN 176
           V  +V I VT  N   P FI  PY + +PE+   GSS+++V   D DT +  +V  SL+ 
Sbjct: 560 VDAQVQITVT-RNQNDPIFINTPYDVTIPESQALGSSVYRVTVTDADTTAPFNVV-SLRA 387

Query: 177 L---HSSKFSMDRHSGVLRLQAGATLDYEKSRAHYITVIAKDGGGRLRGADMVFSATTTV 233
           +    ++ F     +G + ++    LD   +  + + V A+DGG   R      SAT  V
Sbjct: 386 IGDDQATTFFTLADNGTISVRTSLLLD--TNTFYRLRVEARDGGSPAR------SATGLV 231

Query: 234 TINVEDVQDTAPIFVGTPYYGYVYEDTLPGSEVLTVVAIDGDRGKPNHIL-YRLLNES 290
           +INV      AP+FV + Y   + E    G  +L V A D D  +P ++  Y L N++
Sbjct: 230 SINVRR-NLVAPVFVQSSYDATILETQSLGVNILRVAATDADTKRPXNVTQYFLSNDA 60

 Score = 46.2 bits (108), Expect = 6e-05,   Method: Compositional matrix adjust.
 Identities = 54/168 (32%), Positives = 75/168 (44%), Gaps = 11/168 (6%)
 Frame = -2

Query: 454 SSTADIVIQLLDT-NDNVPKFTSHYYIARIPENAPGGSNVVAVTAVDPDT-GPWGKVHYS 511
           S+T D  +Q+  T N N P F +  Y   IPE+   GS+V  VT  D DT  P+  V  S
Sbjct: 569 SATVDAQVQITVTRNQNDPIFINTPYDVTIPESQALGSSVYRVTVTDADTTAPFNVV--S 396

Query: 512 IYGTGSD---LFLIHPSTGLIYTQPWASLDAEGTSRYNFYVKAEDMDGRYSLAEVFVTL- 567
           +   G D    F      G I  +    LD    + Y   V+A D       A   V++ 
Sbjct: 395 LRAIGDDQATTFFTLADNGTISVRTSLLLDTN--TFYRLRVEARDGGSPARSATGLVSIN 222

Query: 568 LDVNDHYPQFVQSVQEKTMV----LGTP-LKIEATDQDAEEPNNLVDY 610
           +  N   P FVQS  + T++    LG   L++ ATD D + P N+  Y
Sbjct: 221 VRRNLVAPVFVQSSYDATILETQSLGVNILRVAATDADTKRPXNVTQY 78
>19334
          Length = 923

 Score = 58.2 bits (139), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 49/142 (34%), Positives = 69/142 (48%), Gaps = 4/142 (2%)
 Frame = +3

Query: 228 SATTTVTINVEDVQDTAPIFVGTPYYGYVYEDTLPGSEVLTVVAIDGDRGKPNHILYRL- 286
           +A   V + +EDV D  P+FV  P+   V  DT  G  V  V A DGD G    I Y L 
Sbjct: 153 TAHVVVMVTIEDVNDNTPMFVKQPFKTIVSTDTEHGETVKKVTAADGDLGDNGEIRYFLP 332

Query: 287 LNESDGI---FEINETSGAISVLQSPALLRREVYELHVQVTEVNSPGSPAAQATVPVTIR 343
           ++ +D +   F IN+ +G I V +     R   + L V+  +    GSP   ATV V I 
Sbjct: 333 MHLTDNVKDAFAINQYTGDIVVRRLTEDDRDTTFLLTVEAVD---QGSPPLSATVEVPIH 503

Query: 344 IVDLNNHPPTFYGESGPQNKFE 365
           +VD ++  P F  +   Q +FE
Sbjct: 504 VVDSSS--PVFESQ---QLRFE 554

 Score = 40.4 bits (93), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 30/122 (24%), Positives = 53/122 (43%), Gaps = 4/122 (3%)
 Frame = +3

Query: 425 ENSAAIDFEKSKLLTFKLLAIEVNTPEKFSSTADIVIQLLDTNDNVPKFTSHYYIARIPE 484
           ++ +  D E+    T  +  +++N PE  ++   +++ + D NDN P F    +   +  
Sbjct: 69  DSRSPFDREQQDQYTVVVQVVDLN-PEPHTAHVVVMVTIEDVNDNTPMFVKQPFKTIVST 245

Query: 485 NAPGGSNVVAVTAVDPDTGPWGKVHY----SIYGTGSDLFLIHPSTGLIYTQPWASLDAE 540
           +   G  V  VTA D D G  G++ Y     +     D F I+  TG I  +     D +
Sbjct: 246 DTEHGETVKKVTAADGDLGDNGEIRYFLPMHLTDNVKDAFAINQYTGDIVVRRLTEDDRD 425

Query: 541 GT 542
            T
Sbjct: 426 TT 431

 Score = 40.0 bits (92), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 47/157 (29%), Positives = 68/157 (43%), Gaps = 13/157 (8%)
 Frame = +3

Query: 537 LDAEGTSRYNFYVKAEDMDGRYSLAEV--FVTLLDVNDHYPQFVQS-----VQEKTMVLG 589
            D E   +Y   V+  D++     A V   VT+ DVND+ P FV+      V   T    
Sbjct: 84  FDREQQDQYTVVVQVVDLNPEPHTAHVVVMVTIEDVNDNTPMFVKQPFKTIVSTDTEHGE 263

Query: 590 TPLKIEATDQDAEEPNNLVDYSITRAEPVNV---FDIDAHTGEI---RLKNSIRSLEALH 643
           T  K+ A D D  + N  + Y +      NV   F I+ +TG+I   RL    R      
Sbjct: 264 TVKKVTAADGDLGD-NGEIRYFLPMHLTDNVKDAFAINQYTGDIVVRRLTEDDR------ 422

Query: 644 NITPSGDYSWSLQVQAKDRGSPSFSTTALLKIDITDT 680
                 D ++ L V+A D+GSP  S T  + I + D+
Sbjct: 423 ------DTTFLLTVEAVDQGSPPLSATVEVPIHVVDS 515
>14391
          Length = 642

 Score = 58.2 bits (139), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 65/228 (28%), Positives = 103/228 (45%), Gaps = 4/228 (1%)
 Frame = +1

Query: 161 DKDTGSGGSVTYSLQNLHSSKFSMDRHSGVLRLQAGATLDYEKSRAHYITVIAKDGGGRL 220
           D D G    + Y ++N +   F++D   G   +     LD E +  +   + A D     
Sbjct: 1   DVDAGDNARLIYGMEN-NGDTFTIDTMLG--DIYTTRFLDRETTPRYVFNIYAYDKSAS- 168

Query: 221 RGADMVFSATTTVTINVEDVQDTAPIFVGTPYYGYVYEDTLPGSEVLTVVAIDGDRGKPN 280
                  +A TTV +NV D  D  P+F+ + Y+ +V E T PGS +  V A+D D G   
Sbjct: 169 -----PLTAVTTVVVNVADKNDMKPVFLNSSYHFHVDERTPPGSMIGDVKAVDKDIGLNA 333

Query: 281 HILYRLL-NESDGIFEIN-ETSGAISVLQSPALLRREVYELHVQVTEVNSPGSPAAQATV 338
            + Y ++ ++S   F I   TSGAI V          ++   V   ++   G+P   +T 
Sbjct: 334 RVEYYMVPSKSRPRFPITVNTSGAILVTDEVDYEMSNLFTFMVAAVDL---GTPPRNSTC 504

Query: 339 PVTIRIVDLNNHPP--TFYGESGPQNKFELSMFEHPPQGEILRGLKIT 384
            VTI ++D N+H P  TF     P  K  L+    PP+ +  + L +T
Sbjct: 505 HVTIEVMDKNDHSPVITFPSPDNPSVKISLT---QPPELKSPKSLPMT 639

 Score = 32.3 bits (72), Expect = 0.87,   Method: Compositional matrix adjust.
 Identities = 52/189 (27%), Positives = 83/189 (43%), Gaps = 8/189 (4%)
 Frame = +1

Query: 499 DPDTGPWGKVHYSIYGTGSDLFLIHPSTGLIYTQPWASLDAEGTSRYNFYVKAEDMDGR- 557
           D D G   ++ Y +   G D F I    G IYT  +  LD E T RY F + A D     
Sbjct: 1   DVDAGDNARLIYGMENNG-DTFTIDTMLGDIYTTRF--LDRETTPRYVFNIYAYDKSASP 171

Query: 558 -YSLAEVFVTLLDVNDHYPQFVQS-----VQEKTMVLGTPLKIEATDQDAEEPNNLVDYS 611
             ++  V V + D ND  P F+ S     V E+T        ++A D+D    N  V+Y 
Sbjct: 172 LTAVTTVVVNVADKNDMKPVFLNSSYHFHVDERTPPGSMIGDVKAVDKDIGL-NARVEYY 348

Query: 612 ITRAEPVNVFDIDAHT-GEIRLKNSIRSLEALHNITPSGDYSWSLQVQAKDRGSPSFSTT 670
           +  ++    F I  +T G I + + +     + N+       ++  V A D G+P  ++T
Sbjct: 349 MVPSKSRPRFPITVNTSGAILVTDEVDY--EMSNL-------FTFMVAAVDLGTPPRNST 501

Query: 671 ALLKIDITD 679
             + I++ D
Sbjct: 502 CHVTIEVMD 528
>13573
          Length = 765

 Score = 57.4 bits (137), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 58/219 (26%), Positives = 103/219 (47%), Gaps = 10/219 (4%)
 Frame = -1

Query: 318 ELHVQVTEVNSPGSPAAQATVPVTIRIVDLNNHPPTFYGESGPQNKFELSMFEHPPQGEI 377
           E+ V V+  +  G P+  A +  T+R++ +   PP FY +  P   F   MFE+ P  ++
Sbjct: 657 EIKVDVSARDVRGDPSQLAVM--TVRVL-VGVRPPQFYED--PYYGF---MFENSPTMQL 502

Query: 378 L-----RGLKITVNDSDQGANAKFNLRLVGPGG----IFRVVPQTVLNEAQVTIIVENSA 428
           +     + LKI+     +G   K    L         +F +  Q +++  QV     +  
Sbjct: 501 VTHEDGKQLKISTVKFQKG---KIRYELYDDASQRSNVFTIDDQGLISNLQVL----DYE 343

Query: 429 AIDFEKSKLLTFKLLAIEVNTPEK-FSSTADIVIQLLDTNDNVPKFTSHYYIARIPENAP 487
           ++D     L    +L +  +   K  S+ A ++I + D NDN P+F +  Y+  + EN P
Sbjct: 342 SVDRSLQPLQYRLVLWVHEDLDXKTLSNNATLIITVQDMNDNKPEFETSQYLTTVRENLP 163

Query: 488 GGSNVVAVTAVDPDTGPWGKVHYSIYGTGSDLFLIHPST 526
             ++V  VTA+D D+G   ++ YS+    S+ F   PS+
Sbjct: 162 VHASVAEVTALDLDSGVNAELEYSV---DSEYFTWRPSS 55

 Score = 41.6 bits (96), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 20/54 (37%), Positives = 30/54 (55%)
 Frame = -1

Query: 121 VVILVTDANDEAPRFIQEPYIIRVPENIPAGSSIFKVQAEDKDTGSGGSVTYSL 174
           ++I V D ND  P F    Y+  V EN+P  +S+ +V A D D+G    + YS+
Sbjct: 249 LIITVQDMNDNKPEFETSQYLTTVRENLPVHASVAEVTALDLDSGVNAELEYSV 88

 Score = 33.9 bits (76), Expect = 0.29,   Method: Compositional matrix adjust.
 Identities = 32/123 (26%), Positives = 57/123 (46%), Gaps = 13/123 (10%)
 Frame = -1

Query: 245 PIFVGTPYYGYVYED-------TLPGSEVLTVVAIDGDRGKPNHILYRLLNESDGIFEIN 297
           P F   PYYG+++E+       T    + L +  +   +GK  + LY   ++   +F I+
Sbjct: 564 PQFYEDPYYGFMFENSPTMQLVTHEDGKQLKISTVKFQKGKIRYELYDDASQRSNVFTID 385

Query: 298 ETSGAISVLQSPAL------LRREVYELHVQVTEVNSPGSPAAQATVPVTIRIVDLNNHP 351
           +  G IS LQ          L+   Y L + V E     + +  AT+ +T++  D+N++ 
Sbjct: 384 D-QGLISNLQVLDYESVDRSLQPLQYRLVLWVHEDLDXKTLSNNATLIITVQ--DMNDNK 214

Query: 352 PTF 354
           P F
Sbjct: 213 PEF 205
>37203
          Length = 818

 Score = 55.5 bits (132), Expect = 9e-08,   Method: Compositional matrix adjust.
 Identities = 51/175 (29%), Positives = 81/175 (46%), Gaps = 11/175 (6%)
 Frame = +3

Query: 133 PRFIQEPYIIRVPENIPAGSSIFKVQAEDK-----DTGSGGSVTYSLQNLH---SSKFSM 184
           P+F Q+ Y   +PE   A  +++K+   ++      T   G VT +L       S  F+ 
Sbjct: 276 PQFFQDSYQGAMPEKNRAQQTVYKLGKTEELQIEWKTFQAGPVTLTLSTDSGQPSGLFAT 455

Query: 185 DRHSGV-LRLQAGATLDYE--KSRAHYITVIAKDGGGRLRGADMVFSATTTVTINVEDVQ 241
            R  G    +     LDYE    +   +T+       R+   D+V   T  V++ +ED  
Sbjct: 456 QRGFGQNTFIVCKQILDYEVVTPKVQQLTLTLTQ---RVGSVDLV--NTVPVSVAIEDTN 620

Query: 242 DTAPIFVGTPYYGYVYEDTLPGSEVLTVVAIDGDRGKPNHILYRLLNESDGIFEI 296
           D  P+F  + Y   V E+ L G  +LTV+A D D G+   I Y LLN +D +F++
Sbjct: 621 DNRPLFDQSQYLYTVKENFLVGENILTVMARDADTGQNAQIDYTLLN-TDNLFQL 782

 Score = 43.9 bits (102), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 21/61 (34%), Positives = 33/61 (54%)
 Frame = +3

Query: 455 STADIVIQLLDTNDNVPKFTSHYYIARIPENAPGGSNVVAVTAVDPDTGPWGKVHYSIYG 514
           +T  + + + DTNDN P F    Y+  + EN   G N++ V A D DTG   ++ Y++  
Sbjct: 582 NTVPVSVAIEDTNDNRPLFDQSQYLYTVKENFLVGENILTVMARDADTGQNAQIDYTLLN 761

Query: 515 T 515
           T
Sbjct: 762 T 764
>37991
          Length = 843

 Score = 54.7 bits (130), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 53/188 (28%), Positives = 79/188 (42%), Gaps = 2/188 (1%)
 Frame = +2

Query: 316 VYELHVQVTEVNSPGSPAAQATVPVTIRIVDLNNHPPTFYGESGPQNKFELSMFEHPPQG 375
            Y L V   +  +  +    +TV + I I D+N++ P F     P   +  S  E    G
Sbjct: 236 TYSLTVTAADDLAGSADEKSSTVVIAIAITDVNDNYPNF----NPA-TYSDSPLETAAAG 400

Query: 376 EILRGLKITVNDSDQGANAKFNLRLVG--PGGIFRVVPQTVLNEAQVTIIVENSAAIDFE 433
             L  L  TV D+D GANA   L +        F +    +       +I  N   +D+E
Sbjct: 401 GTL--LTXTVTDADDGANAVLVLSIASGNTNNAFSLSGNDL-------VIANN---LDYE 544

Query: 434 KSKLLTFKLLAIEVNTPEKFSSTADIVIQLLDTNDNVPKFTSHYYIARIPENAPGGSNVV 493
            +K     + A +  TP   +S A I I +   N++ P  T   + A IPE+   GS + 
Sbjct: 545 TTKNYDLIIEAADSGTPTALTSQARISISVQAANEDPPVLTDTTFAATIPEDQAVGSLIY 724

Query: 494 AVTAVDPD 501
             TA DPD
Sbjct: 725 TATATDPD 748

 Score = 47.0 bits (110), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 38/162 (23%), Positives = 69/162 (42%), Gaps = 1/162 (0%)
 Frame = +2

Query: 121 VVILVTDANDEAPRFIQEPYIIRVPENIPAGSSIFKVQAEDKDTGSGGSVTYSLQNLHSS 180
           + I +TD ND  P F    Y     E   AG ++      D D G+   +  S+ + +++
Sbjct: 308 IAIAITDVNDNYPNFNPATYSDSPLETAAAGGTLLTXTVTDADDGANAVLVLSIASGNTN 487

Query: 181 K-FSMDRHSGVLRLQAGATLDYEKSRAHYITVIAKDGGGRLRGADMVFSATTTVTINVED 239
             FS+  +  V+       LDYE ++ + + + A D      G     ++   ++I+V+ 
Sbjct: 488 NAFSLSGNDLVIANN----LDYETTKNYDLIIEAAD-----SGTPTALTSQARISISVQA 640

Query: 240 VQDTAPIFVGTPYYGYVYEDTLPGSEVLTVVAIDGDRGKPNH 281
             +  P+   T +   + ED   GS + T  A D D+   N 
Sbjct: 641 ANEDPPVLTDTTFAATIPEDQAVGSLIYTATATDPDQDGNND 766

 Score = 39.3 bits (90), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 46/179 (25%), Positives = 74/179 (41%), Gaps = 10/179 (5%)
 Frame = +2

Query: 451 EKFSSTADIVIQLLDTNDNVPKFTSHYYIARIPENAPGGSNVVAVTAVDPDTGPWGKVHY 510
           ++ SST  I I + D NDN P F    Y     E A  G  ++  T  D D G    +  
Sbjct: 284 DEKSSTVVIAIAITDVNDNYPNFNPATYSDSPLETAAAGGTLLTXTVTDADDGANAVLVL 463

Query: 511 SIY-GTGSDLFLIHPSTGLIYTQPWASLDAEGTSRYNFYVKAEDMDGRYSL---AEVFVT 566
           SI  G  ++ F +  +  +I       LD E T  Y+  ++A D     +L   A + ++
Sbjct: 464 SIASGNTNNAFSLSGNDLVIANN----LDYETTKNYDLIIEAADSGTPTALTSQARISIS 631

Query: 567 LLDVNDHYP-----QFVQSVQEKTMVLGTPLKIEATDQDAEEPNN-LVDYSITRAEPVN 619
           +   N+  P      F  ++ E   V        ATD D +  N+  + +SI+  +  N
Sbjct: 632 VQAANEDPPVLTDTTFAATIPEDQAVGSLIYTATATDPDQDGNNDGTITFSISAGDTTN 808

 Score = 33.1 bits (74), Expect = 0.50,   Method: Compositional matrix adjust.
 Identities = 34/132 (25%), Positives = 55/132 (41%), Gaps = 10/132 (7%)
 Frame = +2

Query: 545 YNFYVKAED-----MDGRYSLAEVFVTLLDVNDHYPQF-----VQSVQEKTMVLGTPLKI 594
           Y+  V A D      D + S   + + + DVND+YP F       S  E     GT L  
Sbjct: 239 YSLTVTAADDLAGSADEKSSTVVIAIAITDVNDNYPNFNPATYSDSPLETAAAGGTLLTX 418

Query: 595 EATDQDAEEPNNLVDYSITRAEPVNVFDIDAHTGEIRLKNSIRSLEALHNITPSGDYSWS 654
             TD D +  N ++  SI      N F +  +  ++ + N++   E   N        + 
Sbjct: 419 TVTDAD-DGANAVLVLSIASGNTNNAFSLSGN--DLVIANNLD-YETTKN--------YD 562

Query: 655 LQVQAKDRGSPS 666
           L ++A D G+P+
Sbjct: 563 LIIEAADSGTPT 598

 Score = 31.2 bits (69), Expect = 2.0,   Method: Compositional matrix adjust.
 Identities = 17/42 (40%), Positives = 24/42 (57%), Gaps = 5/42 (11%)
 Frame = +2

Query: 43  SLPEDTPVGSHVYTLNGTDPEGD-----PISYHISFDPSTRS 79
           ++PED  VGS +YT   TDP+ D      I++ IS   +T S
Sbjct: 686 TIPEDQAVGSLIYTATATDPDQDGNNDGTITFSISAGDTTNS 811
>12703
          Length = 1529

 Score = 53.5 bits (127), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 69/257 (26%), Positives = 112/257 (43%), Gaps = 29/257 (11%)
 Frame = -3

Query: 257 YEDTLPGSEVLTVVAIDGDR---------------GKPNHILYRLLNESDGIFEINETSG 301
           Y DT   ++ + + A DGDR               G  NH  +R+L    G    NE   
Sbjct: 780 YSDT---NQTVVMKARDGDRLNSPIDCRMGKTVPAGYENH--FRVLTSRIG--STNEYQC 622

Query: 302 AISVLQSPALLRREVYELHVQV--TEVNSPGSPAAQATVPVTIRIVDLNNHPPTFYGESG 359
            +  LQSP + R  V  L+V +   E++ P   A  A + +T+     N  PPT    SG
Sbjct: 621 RVQ-LQSP-IDRSSVPFLYVVILAVELSDPNFYADDAIIRLTV--FPSNTAPPTITTNSG 454

Query: 360 PQNKFELSMFEHPPQGEILRG-------LKITVND-----SDQGANAKFNLRLVGPGGIF 407
               F   ++E+ P G +++        L++ ++D     SD  AN +    ++ P   F
Sbjct: 453 ---SFVGYVYENAPNGTLVKTDSSLVTVLRLLISDPDVALSDPDANYEI---VLNPATTF 292

Query: 408 RVVPQTVLNEAQVTIIVENSAAIDFEKSKLLTFKLLAIEVNTPEKFSSTADIVIQLLDTN 467
            V      N    ++I+     +D+E      F ++  E++T E+FSST  + + +LD N
Sbjct: 291 EV------NVDSRSVILR--GLLDYETRPSYIFDVIVRELDTEERFSSTVTLTVSVLDVN 136

Query: 468 DNVPKFTSHYYIARIPE 484
           DN P   S  +   +PE
Sbjct: 135 DNAPFIPSAIFNQFVPE 85

 Score = 35.0 bits (79), Expect = 0.14,   Method: Compositional matrix adjust.
 Identities = 23/61 (37%), Positives = 33/61 (54%), Gaps = 1/61 (1%)
 Frame = -1

Query: 461  IQLLDTNDNVPKFTSHYYIARIPENAPGGSNVV-AVTAVDPDTGPWGKVHYSIYGTGSDL 519
            I + D NDN P+F++  Y  +I E  P G  V  ++TA D D G   +V +SI    + L
Sbjct: 1304 IGISDVNDNAPQFSADSYAVQINELTPIGITVYNSITATDLDNGNNKQVVWSIDPATNSL 1125

Query: 520  F 520
            F
Sbjct: 1124 F 1122
>08534
          Length = 885

 Score = 53.1 bits (126), Expect = 5e-07,   Method: Compositional matrix adjust.
 Identities = 60/194 (30%), Positives = 90/194 (46%), Gaps = 17/194 (8%)
 Frame = -3

Query: 490 SNVVAVTAVDPD-TGPWGKVHYSIYGTGS--DLFLIHPSTGLI-YTQPWASLDAEGTSRY 545
           +++  V+A D D   P+  V +SI G  +  + F I+P+TG+I  TQ   SL  +  S Y
Sbjct: 871 ASIFTVSARDNDLQAPYNTVTFSIIGDDAAPNYFNINPNTGVISVTQ---SLFGDSASSY 701

Query: 546 NFYVKAEDMDGRYSLA--EVFVTLLDVNDHYPQFVQS----VQEKTMVLGTP------LK 593
              ++A D  G+ SL   EV    +D N   P +V          T VL T         
Sbjct: 700 RLRIQASD-GGKPSLVDYEVVTINVDRNSFTPSWVNPSAPFYTSTTQVLETIDYSTILFS 524

Query: 594 IEATDQDAEEPNNLVDYS-ITRAEPVNVFDIDAHTGEIRLKNSIRSLEALHNITPSGDYS 652
           + A D D   P N V YS + + +    FD++  +GEIRL++S+             D S
Sbjct: 523 VSARDNDIIAPYNQVTYSLVNQGKAPTFFDVNPTSGEIRLRSSLLQ---------DTDQS 371

Query: 653 WSLQVQAKDRGSPS 666
           +S+ + A D G PS
Sbjct: 370 YSVLLTAADNGIPS 329

 Score = 50.8 bits (120), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 71/272 (26%), Positives = 116/272 (42%), Gaps = 13/272 (4%)
 Frame = -3

Query: 67  ISYHISFDPSTRSVFSVDPNFGNITLVXXXXXXXXXXXXXXXXXXXG--LNLVAEKVVIL 124
           +++ I  D +  + F+++PN G I++                    G   +LV  +VV +
Sbjct: 814 VTFSIIGDDAAPNYFNINPNTGVISVTQSLFGDSASSYRLRIQASDGGKPSLVDYEVVTI 635

Query: 125 VTDANDEAPRFIQ--EPY---IIRVPENIPAGSSIFKVQAEDKDT-GSGGSVTYSLQNLH 178
             D N   P ++    P+     +V E I   + +F V A D D       VTYSL N  
Sbjct: 634 NVDRNSFTPSWVNPSAPFYTSTTQVLETIDYSTILFSVSARDNDIIAPYNQVTYSLVNQG 455

Query: 179 SSK--FSMDRHSGVLRLQAGATLDYEKSRAHYITVIAKDGGGRLRGADMVFSATTTVTIN 236
            +   F ++  SG +RL++    D ++S +  +T  A D G        V   T TV +N
Sbjct: 454 KAPTFFDVNPTSGEIRLRSSLLQDTDQSYSVLLT--AADNGI----PSEVALQTATVVVN 293

Query: 237 VEDVQDTAPIFVGTPYYGYVYEDTLPGSEVLTVVAIDGDRGKPNHIL-YRLLNESDGI-- 293
           V    +T P FVG+PY   + E T  GS + ++ A D D       L Y ++ +      
Sbjct: 292 VLRNLNT-PYFVGSPYAITIAETTSVGSSIFSLTARDDDLANTFETLSYDIIGDDAATVY 116

Query: 294 FEINETSGAISVLQSPALLRREVYELHVQVTE 325
           F +   SG + V    +     VY + V+V +
Sbjct: 115 FTVESFSGIVRVGSDLSATTDSVYYVRVRVRD 20

 Score = 43.1 bits (100), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 26/92 (28%), Positives = 46/92 (50%), Gaps = 3/92 (3%)
 Frame = -3

Query: 129 NDEAPRFIQEPYIIRVPENIPAGSSIFKVQAEDKDTGSG-GSVTYSL--QNLHSSKFSMD 185
           N   P F+  PY I + E    GSSIF + A D D  +   +++Y +   +  +  F+++
Sbjct: 283 NLNTPYFVGSPYAITIAETTSVGSSIFSLTARDDDLANTFETLSYDIIGDDAATVYFTVE 104

Query: 186 RHSGVLRLQAGATLDYEKSRAHYITVIAKDGG 217
             SG++R+  G+ L       +Y+ V  +D G
Sbjct: 103 SFSGIVRV--GSDLSATTDSVYYVRVRVRDNG 14
>38442
          Length = 393

 Score = 47.4 bits (111), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 28/91 (30%), Positives = 49/91 (53%)
 Frame = -3

Query: 422 IIVENSAAIDFEKSKLLTFKLLAIEVNTPEKFSSTADIVIQLLDTNDNVPKFTSHYYIAR 481
           I+VE    +D EK      +++A +   P++ S + +I I + D NDNVP F+   +   
Sbjct: 277 IVVEQ--PLDREKMSSYFLQVVASDGGFPQR-SGSVNITINVQDVNDNVPTFSRELFNIT 107

Query: 482 IPENAPGGSNVVAVTAVDPDTGPWGKVHYSI 512
           + E++P G  ++ + A DPD+   G + YS 
Sbjct: 106 VNEDSPTGVAILRLNATDPDSSHNGALTYSF 14

 Score = 43.1 bits (100), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 21/55 (38%), Positives = 31/55 (56%)
 Frame = -3

Query: 120 KVVILVTDANDEAPRFIQEPYIIRVPENIPAGSSIFKVQAEDKDTGSGGSVTYSL 174
            + I V D ND  P F +E + I V E+ P G +I ++ A D D+   G++TYS 
Sbjct: 178 NITINVQDVNDNVPTFSRELFNITVNEDSPTGVAILRLNATDPDSSHNGALTYSF 14

 Score = 29.3 bits (64), Expect = 6.4,   Method: Compositional matrix adjust.
 Identities = 28/121 (23%), Positives = 51/121 (42%)
 Frame = -3

Query: 276 RGKPNHILYRLLNESDGIFEINETSGAISVLQSPALLRREVYELHVQVTEVNSPGSPAAQ 335
           +G P      LL  +     ++  S  + ++    L R ++    +QV   +  G P   
Sbjct: 364 QGVPPATRPGLLPPAGSTSSVDGVSSDLGIVVEQPLDREKMSSYFLQVVASDG-GFPQRS 188

Query: 336 ATVPVTIRIVDLNNHPPTFYGESGPQNKFELSMFEHPPQGEILRGLKITVNDSDQGANAK 395
            +V +TI + D+N++ PTF  E      F +++ E  P G  +  L++   D D   N  
Sbjct: 187 GSVNITINVQDVNDNVPTFSRE-----LFNITVNEDSPTGVAI--LRLNATDPDSSHNGA 29

Query: 396 F 396
            
Sbjct: 28  L 26
>27585
          Length = 389

 Score = 47.0 bits (110), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 38/110 (34%), Positives = 55/110 (50%), Gaps = 2/110 (1%)
 Frame = -3

Query: 430 IDFEKSKLLTFKLLAIEV--NTPEKFSSTADIVIQLLDTNDNVPKFTSHYYIARIPENAP 487
           +D+E   L    LL +E      ++ SSTA + I +LD  DNVP F    Y A + EN+ 
Sbjct: 366 LDYEIQSLY---LLVVEAADGAVDRRSSTATVTIYVLDVEDNVPIFVRSLYTASVTENS- 199

Query: 488 GGSNVVAVTAVDPDTGPWGKVHYSIYGTGSDLFLIHPSTGLIYTQPWASL 537
             + V  VTA DPD+     V Y + G  +  F I  S+G+ + Q  + L
Sbjct: 198 NNALVTTVTAEDPDS--IKNVVYELIGNDASAFSI--SSGVKFHQRRSGL 61

 Score = 45.1 bits (105), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 37/99 (37%), Positives = 50/99 (50%)
 Frame = -3

Query: 199 LDYEKSRAHYITVIAKDGGGRLRGADMVFSATTTVTINVEDVQDTAPIFVGTPYYGYVYE 258
           LDYE    + + V A DG    R      S+T TVTI V DV+D  PIFV + Y   V E
Sbjct: 366 LDYEIQSLYLLVVEAADGAVDRR------SSTATVTIYVLDVEDNVPIFVRSLYTASVTE 205

Query: 259 DTLPGSEVLTVVAIDGDRGKPNHILYRLLNESDGIFEIN 297
           ++   + V TV A D D  K  +++Y L+      F I+
Sbjct: 204 NS-NNALVTTVTAEDPDSIK--NVVYELIGNDASAFSIS 97
>33084
          Length = 694

 Score = 43.9 bits (102), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 41/170 (24%), Positives = 70/170 (41%), Gaps = 19/170 (11%)
 Frame = +3

Query: 43  SLPEDTPVGSHVYTLNGTDPE-GDPISYHISFDPSTRSVFSVDPNFG-------NITLVX 94
           S+ E+ P+GS + TL+ +D      + Y +  D   + VF+++   G        + L  
Sbjct: 180 SISENLPIGSSILTLSASDVNLAGSLRYSVDGDYPAQYVFNLNQTTGVQAVITNYLNLRT 359

Query: 95  XXXXXXXXXXXXXXXXXXGLNLVAEKVVILVTDANDEAPRFIQEPYIIRVPENIPAGSSI 154
                               N  + +V  +    N+  PR++  PYI  + E+ P  SS+
Sbjct: 360 ETLGETEYRLRIVVYDSLRENRRSTRVCTITVRRNENGPRWLAPPYIFPISEDKPYISSV 539

Query: 155 FKVQAEDKDTGSGGSVTYSL-----------QNLHSSKFSMDRHSGVLRL 193
             V A D D   G ++TY +           QN  S  F ++R +G+L L
Sbjct: 540 GPVTATDDD--PGDTITYRIVTEFAERNNLNQNSPSIYFQINRDTGMLNL 683
>15121
          Length = 2573

 Score = 41.2 bits (95), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 46/144 (31%), Positives = 69/144 (47%), Gaps = 6/144 (4%)
 Frame = +3

Query: 228 SATTTVTINVEDVQDTAP-IFVGTPYYGYVYEDTLP--GSEVLTVVAIDGDRGKPNHILY 284
           S +T VTI V D+ D AP I   T     V   T+P  G  +  V+A D D G  + ++Y
Sbjct: 297 SNSTQVTIKVSDINDNAPVILFPTNANHSVVISTVPEKGVTLGRVIAYDVDEGNASSLIY 476

Query: 285 RLL-NESDGIFEINETSGAISVLQSPALLRRE-VYELHVQVTEVN-SPGSPAAQATVPVT 341
            ++  ++ G+F+I   +G I  L +P  LR   VY + ++V +   +P     +  + V 
Sbjct: 477 AIIGGDARGVFDIKPKTGEI-YLDNPVRLRNPFVYHVVLRVYDTGPNPRFAETRLQIDVN 653

Query: 342 IRIVDLNNHPPTFYGESGPQNKFE 365
            R V    HP    G SG QN  E
Sbjct: 654 FRNV---THPG---GTSGSQNGAE 707

 Score = 39.3 bits (90), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 47/171 (27%), Positives = 74/171 (43%), Gaps = 16/171 (9%)
 Frame = +3

Query: 523 HPSTGLIYTQPW--ASLDAEGTSRYNFYVKAEDMDG--RYSLAEVFVTLLDVNDHYPQF- 577
           +PS      Q W  A       SR       ED     R +  +V + + D+ND+ P   
Sbjct: 180 YPSQYTATAQWWWRACWTERRASRTCSRCWREDKGAIPRSNSTQVTIKVSDINDNAPVIL 359

Query: 578 ----------VQSVQEKTMVLGTPLKIEATDQDAEEPNNLVDYSITRAEPVNVFDIDAHT 627
                     + +V EK + LG   ++ A D D    ++L+ Y+I   +   VFDI   T
Sbjct: 360 FPTNANHSVVISTVPEKGVTLG---RVIAYDVDEGNASSLI-YAIIGGDARGVFDIKPKT 527

Query: 628 GEIRLKNSIRSLEALHNITPSGDYSWSLQVQAKDRG-SPSFSTTALLKIDI 677
           GEI L N +R    L N      + + + ++  D G +P F+ T  L+ID+
Sbjct: 528 GEIYLDNPVR----LRN-----PFVYHVVLRVYDTGPNPRFAETR-LQIDV 650
>14137
          Length = 815

 Score = 39.7 bits (91), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 48/192 (25%), Positives = 82/192 (42%), Gaps = 15/192 (7%)
 Frame = -1

Query: 340 VTIRIVDLNNHPPTFYG------ESGPQNKFELSMFEHPPQGEILRGLKITVNDSDQGAN 393
           +T+ + D+N + P F        ++   +   +++ E  P G ++  L+++  D+D G N
Sbjct: 722 LTVFVQDVNINEPKFVAPDESLVDTAANSLPNITVDEEQPIGSLI--LQLSATDADTGNN 549

Query: 394 AK----FNLRLVGPGGIFRVVPQTVLNEAQVTIIVENSAAIDFEKSKLLTFKLLAIEVNT 449
            +     +  L G    F V          V+  + N   +D E++ +    L A +  T
Sbjct: 548 GQVFYGLDPDLSGQFNSFSV--------DAVSGNLTNKQILDREQTDMFQISLKAEDQGT 393

Query: 450 PEKFSSTADIVIQLLDTNDNVPKF----TSHYYIARIPENAPGGSNVVAVTAVDPDTGPW 505
           P + S+     + L D NDN P+F    T    +    +N   GS  +   AVD D  P 
Sbjct: 392 PTRLSTVIPFRVFLRDVNDNDPRFPPPATLTLSVGEELQNVVVGSVDI---AVDDDHDPE 222

Query: 506 GK-VHYSIYGTG 516
            K + Y IYG G
Sbjct: 221 NKIICYYIYGGG 186
>17610
          Length = 446

 Score = 38.5 bits (88), Expect = 0.012,   Method: Compositional matrix adjust.
 Identities = 35/123 (28%), Positives = 51/123 (41%), Gaps = 5/123 (4%)
 Frame = -1

Query: 130 DEAPRFIQEPYIIRVPENIPAGSSIFKVQAEDKDTGSGGSVTYSLQNLHSSKFSMDRHSG 189
           +E P F Q  Y   +PE+ P GS+  ++Q+   D        + L   +S +F   R   
Sbjct: 335 NEPPVFDQTTYYCTMPESGPTGSAC-QLQSTVTDPEGDTIDLFELSGTNSDRFQYVRADD 159

Query: 190 VLRLQAGATLDYEKSRAHY-----ITVIAKDGGGRLRGADMVFSATTTVTINVEDVQDTA 244
            +R     T+DY+    +Y     IT+ A D   R   A        T+ I VEDV D  
Sbjct: 158 EIRF----TIDYDVDNGNYPTSAVITINAVDSNKRTGSA--------TIDITVEDVNDNT 15

Query: 245 PIF 247
             F
Sbjct: 14  CSF 6
>38001
          Length = 884

 Score = 37.4 bits (85), Expect = 0.027,   Method: Compositional matrix adjust.
 Identities = 43/140 (30%), Positives = 65/140 (46%), Gaps = 6/140 (4%)
 Frame = -3

Query: 115 NLVAEKVVILVTDANDEAPRFIQEPYIIRVPENIPAGSSIFKVQAEDKDTGSGGSVTY-- 172
           + V     I V D ND  P+FI     + + E  P+  ++  V+AED D  +  ++TY  
Sbjct: 798 DFVYYDTKIFVMDVNDNDPQFIDLTTTLTLNELTPSDVAVLTVKAEDLDLNA--NLTYSI 625

Query: 173 ----SLQNLHSSKFSMDRHSGVLRLQAGATLDYEKSRAHYITVIAKDGGGRLRGADMVFS 228
               SL +  S  F ++  SG L ++    LDYE      + +  +D G   R      +
Sbjct: 624 VPRPSLADDMSGYFEVNASSGELTVKDH--LDYETMAEGTLVLAVEDSGSPSR------T 469

Query: 229 ATTTVTINVEDVQDTAPIFV 248
           AT TV + VED  D  P+FV
Sbjct: 468 ATATVAVVVEDGDDQGPVFV 409
>18019
          Length = 571

 Score = 34.7 bits (78), Expect = 0.16,   Method: Compositional matrix adjust.
 Identities = 35/145 (24%), Positives = 57/145 (39%), Gaps = 5/145 (3%)
 Frame = -1

Query: 52  SHVYTLNGTDPEGDPISYHISFDPSTRSVFSVDPNFGNITL---VXXXXXXXXXXXXXXX 108
           S + T++  DP+GD  SY +         F + P+ G + L   +               
Sbjct: 571 SQLLTVSAVDPDGDIPSYRLLNVGQCLEYFYISPDSGVVNLRKPLYTNNINQYVCIVQAS 392

Query: 109 XXXXGLNLVAEKVVILVTDANDEAPRFIQEPYIIRVPENIPAGSSIFKVQAEDKDTGSGG 168
                  L    V I V  +  + PRF   PY   V E    G+S+++V A D D    G
Sbjct: 391 DQRSNARLTNATVTINVIRS--QPPRFQNTPYSFTVSERTSVGASVYRVTAFDADL--DG 224

Query: 169 SVTYSLQNL--HSSKFSMDRHSGVL 191
            + Y +  +    S F ++  +GV+
Sbjct: 223 VLVYEVVGVAPAPSYFQLNTTTGVI 149

 Score = 31.2 bits (69), Expect = 2.0,   Method: Compositional matrix adjust.
 Identities = 31/108 (28%), Positives = 48/108 (44%), Gaps = 3/108 (2%)
 Frame = -1

Query: 471 PKFTSHYYIARIPENAPGGSNVVAVTAVDPDTGPWGKVHYSIYGT--GSDLFLIHPSTGL 528
           P+F +  Y   + E    G++V  VTA D D    G + Y + G       F ++ +TG+
Sbjct: 325 PRFQNTPYSFTVSERTSVGASVYRVTAFDADLD--GVLVYEVVGVAPAPSYFQLNTTTGV 152

Query: 529 IYTQPWASLDAEGTSRYNFYVKAEDMDGRYSLAEVFVTLLDV-NDHYP 575
           I   P   L  + T  Y   V+A D      + E  V++  V ND+ P
Sbjct: 151 I--SPRVDLKVDTTQNYLLRVRAYDSAFPTQVTEADVSIFVVRNDNPP 14
>33808
          Length = 445

 Score = 34.3 bits (77), Expect = 0.20,   Method: Compositional matrix adjust.
 Identities = 27/85 (31%), Positives = 41/85 (48%), Gaps = 2/85 (2%)
 Frame = +3

Query: 471 PKFTSHYYIARIPENAPGGSNVVAVTAVDPDTGPWGKVHYSIYGT--GSDLFLIHPSTGL 528
           P F S  Y   I  +    + VV  TAVD D    G + YS+ G       F I+P++G 
Sbjct: 27  PNFVSLPYRTTIQRSTAINATVVRATAVDADL--QGVIRYSVVGNYPAPTFFDINPASGD 200

Query: 529 IYTQPWASLDAEGTSRYNFYVKAED 553
           I+ +   +LD+  +++Y   V A D
Sbjct: 201 IFVKQSLALDSLLSTQYIVAVIAYD 275

 Score = 28.9 bits (63), Expect = 9.6,   Method: Compositional matrix adjust.
 Identities = 24/70 (34%), Positives = 32/70 (45%), Gaps = 2/70 (2%)
 Frame = +3

Query: 244 APIFVGTPYYGYVYEDTLPGSEVLTVVAIDGDRGKPNHILYRLLNE--SDGIFEINETSG 301
           AP FV  PY   +   T   + V+   A+D D      I Y ++    +   F+IN  SG
Sbjct: 24  APNFVSLPYRTTIQRSTAINATVVRATAVDADLQ--GVIRYSVVGNYPAPTFFDINPASG 197

Query: 302 AISVLQSPAL 311
            I V QS AL
Sbjct: 198 DIFVKQSLAL 227
>29111
          Length = 320

 Score = 31.2 bits (69), Expect = 1.7,   Method: Compositional matrix adjust.
 Identities = 32/96 (33%), Positives = 44/96 (45%)
 Frame = +2

Query: 482 IPENAPGGSNVVAVTAVDPDTGPWGKVHYSIYGTGSDLFLIHPSTGLIYTQPWASLDAEG 541
           + EN   GS V  VT      G    +  +    G+ +F +  STG I T+  A+LD E 
Sbjct: 35  VEENVANGSYVGTVTNPANTAGFNDLIPGNAQQDGTQVFSVVLSTGRITTK--ANLDRE- 205

Query: 542 TSRYNFYVKAEDMDGRYSLAEVFVTLLDVNDHYPQF 577
           T    FY      +   ++  V V LLDVND+ P F
Sbjct: 206 TVPSGFYSFLLQTNNSGTIVLVIVRLLDVNDNDPSF 313
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|37537518|ref|NP_076027.1| acylglycerol kinase [Mus
musculus]
         (421 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

09475                                                                 140   8e-34
18156                                                                  67   1e-11
04667                                                                  59   3e-09
16162                                                                  29   4.4  
>09475
          Length = 3978

 Score =  140 bits (354), Expect = 8e-34,   Method: Compositional matrix adjust.
 Identities = 97/311 (31%), Positives = 157/311 (50%), Gaps = 20/311 (6%)
 Frame = -1

Query: 116  TDVIIVAGGDGTLQEVVTGVLRRTDEATFSKIPIGFIPLGQTSSLSHTLFAESGNKVQHI 175
            T  I+VAGGDGTL E VTG+LR+ D+  F KIP+G IP+G T++ +   +      V+ +
Sbjct: 1878 TQAILVAGGDGTLIEAVTGILRKEDKK-FHKIPVGVIPVGNTNTFARLFYGADKASVRMM 1702

Query: 176  TDATLAIVKGETVPLDVLQIKGEKEQPVYAMTGLRWGSFRDAGVKVSKYWYLGPLKTKAA 235
             DA +A+VK  T  +DVL++ G + +  +A+ G+  G++RDA  + SKYWY GPLK++  
Sbjct: 1701 ADAAMAVVKNVTKKVDVLKVDGGEGKTTFALCGMEIGAYRDAEERKSKYWYFGPLKSRWT 1522

Query: 236  HFFSTLQEWPQTHQASISYTGXXXXXXXXXXXXXXXXS----------LYRRILRRLASF 285
            +  + ++ WP    A +SY                             L+RR  + +   
Sbjct: 1521 YMRTAMKSWPPAINAKVSYVEATPENMKYXEVEDDPPPNQSPWRFWHFLFRR--KPVTHV 1348

Query: 286  WAQPQDASSREVSPEVWKDVQLSTIELSITTRNTQLDLMSKEDFMNICIEPDTVSKGDFI 345
              Q ++    E   E     +LST+ELS+ + N  +D   +   +   + P   ++ D I
Sbjct: 1347 VEQKKEEEKEEEEEEERVSAELSTVELSLMSPN--MDSTKEVAGIRFEVGPTEPTRSDLI 1174

Query: 346  IIGSKKVRDPGLRAAGTEC-------LQASHCTLVLPEGTEGS---FSIDSEEYEAMPVE 395
              G +++   G ++    C       ++     L LP+  EG    ++ID E +EA+PV 
Sbjct: 1173 KEGWERI---GRKSPKYGCDSNQRFLVKDVSIELDLPQQEEGPPVWYNIDGESFEAIPVT 1003

Query: 396  VKLLPRKLRFF 406
            V LL +KL FF
Sbjct: 1002 VSLLQKKLNFF 970
>18156
          Length = 421

 Score = 67.0 bits (162), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 37/141 (26%), Positives = 74/141 (52%), Gaps = 4/141 (2%)
 Frame = -2

Query: 75  KARTLFEKNAAPILHLSGMDVTVVKTDYEGQAKKLLELMESTD--VIIVAGGDGTLQEVV 132
           +A  +F+    P+   + +   +V T+Y G A+ L+  +E ++   II+  GDG + EV+
Sbjct: 420 RAMHIFKHEVEPMFEEASIPFKLVVTEYAGHAQDLMHNLELSEWAAIIIVSGDGLVYEVI 241

Query: 133 TGVLRRTDEATFSKIPIGFIPLGQTSSLSHTLFAESGNK--VQHITDATLAIVKGETVPL 190
            G++ R D  +  K P+G +P G  ++L+ +L   +G    V  +  +T  ++K   VP+
Sbjct: 240 NGLMHREDWTSAIKKPLGCLPGGSGNALACSLNYAAGEPVLVNPVLHSTFVLIKHRVVPM 61

Query: 191 DVLQIKGEKEQPVYAMTGLRW 211
           D++ ++    Q  Y+   + W
Sbjct: 60  DLVLVQTPSRQH-YSFLSVAW 1
>04667
          Length = 1874

 Score = 59.3 bits (142), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 38/148 (25%), Positives = 75/148 (50%), Gaps = 13/148 (8%)
 Frame = -1

Query: 61   KKATVFLNPAACKGKARTLFEKNAAPILHLSGM--DVTVVKTDYEGQAKKLLELMESTDV 118
            K   VFL P A     R++++     I   +G+  D+TV++ +   + + +   +   D 
Sbjct: 1703 KNVKVFLQPYAGDKNGRSIYKHKVLSIFQNAGVAADLTVIQHNEHVKQEMIHLNVYDFDC 1524

Query: 119  IIVAGGDGTLQEVVTGVLRRTDEATFSK-----------IPIGFIPLGQTSSLSHTLFAE 167
            +I  GGDGT+ +V+ G+++R+ +   ++           +P+G IP+G+T+ ++ ++   
Sbjct: 1523 VIAMGGDGTVHQVLNGLMQRSQKENETELKVGTNPARALVPMGIIPIGKTNQIACSVMG- 1347

Query: 168  SGNKVQHITDATLAIVKGETVPLDVLQI 195
                V  +T A L IV G   P+DV  +
Sbjct: 1346 ---TVDPVT-AALHIVFGRWTPVDVCSV 1275
>16162
          Length = 1046

 Score = 28.9 bits (63), Expect = 4.4,   Method: Compositional matrix adjust.
 Identities = 28/88 (31%), Positives = 38/88 (43%), Gaps = 2/88 (2%)
 Frame = -3

Query: 123 GGDGTLQEVVTGVLRRTDEATFSKIPIGFIP-LGQTSSLSHTLFAESGNKVQHITDATLA 181
           G +GT  + V   L  T    F K    F P LGQ+ SLS  L A+S +  +    +  A
Sbjct: 567 GLNGTFFDSVVSFLFMTFS*LFGKRVSRFPPSLGQSISLSAILGADSSDNTRLPMQSLSA 388

Query: 182 IVKGETVPLDVLQI-KGEKEQPVYAMTG 208
           +V   T PL    + K     P   +TG
Sbjct: 387 VVSSITSPLPSATVSKSLSASPRTLLTG 304
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|119964716|ref|NP_082470.2| furry homolog-like isoform
1 [Mus musculus]
         (3007 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

22794                                                                  89   1e-33
09084                                                                  32   2.8  
27348                                                                  31   9.0  
>22794
          Length = 613

 Score = 89.4 bits (220), Expect(2) = 1e-33,   Method: Compositional matrix adjust.
 Identities = 40/85 (47%), Positives = 57/85 (67%)
 Frame = -3

Query: 1079 SHWAGPFSIMFTPLDRYSDRNMQINRHQYCALKAMSAVLCCGPVADNVGLSSDGYLYKWL 1138
            ++W+G FS+ +  LDR  ++    +  +  A+KAMSAVLCCGPV DN G + DGY+Y WL
Sbjct: 257  ANWSGHFSLTYGTLDRRLNKEESWSEQELSAVKAMSAVLCCGPVFDNNGFNDDGYIYHWL 78

Query: 1139 DNILDSLDKKVHQLGCEAVTLLLEL 1163
            D +L S D+K++ L  E V LLL+ 
Sbjct: 77   DTLLSSSDEKIYMLAKETVYLLLDF 3

 Score = 74.7 bits (182), Expect(2) = 1e-33,   Method: Compositional matrix adjust.
 Identities = 36/90 (40%), Positives = 59/90 (65%)
 Frame = -1

Query: 988  FELLADAGVISHSASGGLDSETHFLNNTLLEYVDLTRQLLEAENEKDSDTLKDIRCHFSA 1047
            F+LLA+  V   S +G +D+ET  L +  ++Y+D  RQ LE EN++D   L++IR HFS 
Sbjct: 526  FQLLAENKVFGQSEAGAIDTETGQLTSMFVDYIDGARQYLEGENDRDLPILQEIRLHFSC 347

Query: 1048 LVANIIQNVPVHQRRSIFPQQSLRHSLFML 1077
             + ++I N P+  R+++  ++ LR+SLF L
Sbjct: 346  FLQHLINNTPMEYRKTLLSRE-LRYSLFHL 260
>09084
          Length = 868

 Score = 32.3 bits (72), Expect = 2.8,   Method: Composition-based stats.
 Identities = 28/101 (27%), Positives = 45/101 (44%), Gaps = 22/101 (21%)
 Frame = -1

Query: 313 LYPLITCLLCVSQKQFFL---NNWHIFL-QNCLSHLKNKDPKMSRVALESLYRLLWVYVI 368
           L+P I+CL  +    FF+    N H+FL  +CL+ LK K   +    +  L++  W++  
Sbjct: 643 LFPFISCLNILDLYNFFIKCKKNSHLFLFISCLNILKCKIFLLFVQFI--LFKYSWLFFF 470

Query: 369 RIKCES------------------NTVTQSRLMSIVSALFP 391
            IKC+                   N    S L ++VS L+P
Sbjct: 469 SIKCKKLCRVCSLIKCLNEDYFLINCKKISALFAVVSCLYP 347
>27348
          Length = 436

 Score = 30.8 bits (68), Expect = 9.0,   Method: Compositional matrix adjust.
 Identities = 15/35 (42%), Positives = 20/35 (57%)
 Frame = +3

Query: 1492 TDGNPDSKALKENFEESYVHLDIYGGLNSHLNRQH 1526
            TD  PD   + E+F +SY HLD +   +SH N  H
Sbjct: 57   TDSRPDLFGVSESFPDSYSHLDWHSTAHSHSNLGH 161
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|17998694|ref|NP_032079.1| fragile X mental
retardation-related protein 1 isoform 3 [Mus musculus]
         (539 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

19295                                                                 140   1e-33
20748                                                                  33   0.29 
09541                                                                  32   0.67 
26269                                                                  32   0.93 
>19295
          Length = 419

 Score =  140 bits (353), Expect = 1e-33,   Method: Composition-based stats.
 Identities = 73/139 (52%), Positives = 97/139 (69%), Gaps = 1/139 (0%)
 Frame = +3

Query: 144 ENAHKDFKKAVGA-CRIFYHPETTQLMILSASEATVKRVNILSDMHLRSIRTKLMLMSRN 202
           E A  + KK +G    + Y+     + +L+ S A  KR +++ DM LR++R KL+L  R 
Sbjct: 3   EGALSELKKHLGGGAMVSYNTADNSIHVLATSTAVTKRASMIGDMFLRNVRQKLLLKMRT 182

Query: 203 EEATKHLECTKQLAAAFHEEFVVREDLMGLAIGTHGSNIQQARKVPGVTAIELDEDTGTF 262
           EEA K L+ TK + + + EEF VREDLMGLAIGTHG+NIQQARK+  +T IELDE T TF
Sbjct: 183 EEAVKKLQSTK-IRSGYMEEFAVREDLMGLAIGTHGANIQQARKIEHITGIELDESTCTF 359

Query: 263 RIYGESAEAVKKARGFLEF 281
           ++YGE+ EAVK+ARG LEF
Sbjct: 360 KVYGETTEAVKQARGMLEF 416
>20748
          Length = 847

 Score = 33.1 bits (74), Expect = 0.29,   Method: Compositional matrix adjust.
 Identities = 14/26 (53%), Positives = 18/26 (69%)
 Frame = -2

Query: 286 IQVPRNLVGKVIGKNGKVIQEIVDKS 311
           I  P NL G++IGK G VI+  +DKS
Sbjct: 654 ILCPNNLCGRIIGKKGIVIKGFMDKS 577
>09541
          Length = 2010

 Score = 32.0 bits (71), Expect = 0.67,   Method: Compositional matrix adjust.
 Identities = 19/44 (43%), Positives = 31/44 (70%), Gaps = 3/44 (6%)
 Frame = -1

Query: 286 IQVPRNLVGKVIGKNGKVIQEIVDKSGVVRVRI---EGDNENKL 326
           I VPR  VG VIGK G++I++I ++SG  +V+    +G +E++L
Sbjct: 234 IPVPRQAVGLVIGKGGEMIKKIQNESG-AKVQFKPDDGQSEDRL 106
>26269
          Length = 679

 Score = 31.6 bits (70), Expect = 0.93,   Method: Compositional matrix adjust.
 Identities = 28/121 (23%), Positives = 48/121 (39%), Gaps = 29/121 (23%)
 Frame = -3

Query: 216 AAAFHEEFVVREDLMGLAIGTHGSNIQQARKVPGVTAIELDEDTGT------FRIYGESA 269
            AA      +    +GL IG  G  I+Q ++  GV  + + +           RI G++ 
Sbjct: 677 GAALWWRCPIPGPKVGLIIGKGGETIRQLQERAGVKMVMIQDSNAPSAADKPLRISGDAP 498

Query: 270 EAVKKARGFLEFVEDF-----------------------IQVPRNLVGKVIGKNGKVIQE 306
           +  +     +E +++                        I VPR  VG VIGK G++I++
Sbjct: 497 KCQRAKEMVIELLQEKADVPAPGFNNFDNMGPGGPGGIEIPVPRQAVGLVIGKGGEMIKK 318

Query: 307 I 307
           I
Sbjct: 317 I 315
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|54607114|ref|NP_001005868.1| Erbb2 interacting
protein isoform 1 [Mus musculus]
         (1450 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

34576                                                                 142   1e-33
09309                                                                  79   9e-15
19531                                                                  71   3e-12
20480                                                                  67   4e-11
05532                                                                  51   3e-06
30747                                                                  49   1e-05
19955                                                                  42   0.003
20073                                                                  38   0.028
01502                                                                  37   0.068
02951                                                                  37   0.075
29705                                                                  36   0.15 
00779                                                                  35   0.27 
26556                                                                  30   6.8  
17298                                                                  30   6.8  
20775                                                                  30   8.5  
>34576
          Length = 1496

 Score =  142 bits (357), Expect = 1e-33,   Method: Compositional matrix adjust.
 Identities = 103/327 (31%), Positives = 160/327 (48%), Gaps = 3/327 (0%)
 Frame = +2

Query: 78  DNDLTTLPASIANLINLRELDVSKNGIQEFPENIKNCKVLTIVEASVNPISKLPDGFSQL 137
           +N LT LP  IA L  L+E+    N +   PE+I  C  L I+    N + +LP  F+ L
Sbjct: 5   NNCLTVLPEDIAELFELKEVYCGSNQLTLIPESICWCSNLEILSLHKNHLERLPVEFANL 184

Query: 138 LNLTQLYLNDAFLEFLPANFGRLTKLQILELRENQLKMLPKTMNRLTQLERLDLGSNEFT 197
             +T+L L+D     +P   G LT+L+ L L  N L  +P+ +  L +L  L LG N F 
Sbjct: 185 RKITRLILSDNNFTSVPVAIGSLTELEALLLDGNSLHEIPQELGTLKKLTHLSLGRNAFK 364

Query: 198 EVPEVLEQLSGLREFWMDGNRLTFIPGFIGSLRQLTYLDVSKNNIEMVEEGISTCENLQD 257
           E P     ++ L    +  N++T IP  I  L  L  L + KN + +    +   + LQ 
Sbjct: 365 EFPRPACSITSLEILDLSDNKITEIPSDIAQLLSLRELYMKKNAVSVFCAELCALQKLQM 544

Query: 258 FLLSSNSLQQLPETIGSLKNVTTLKIDENQLMYLPDSIGGLRSIEELDCSFNE---IEAL 314
              S+N L  LPE +  L  +  L +  NQ    P +   +  + +L  S  E   + +L
Sbjct: 545 ADFSNNGLLDLPEEVSVLGCLQELDLSNNQFFEFPKTACSIPHLHKLVFSQQEGLKVPSL 724

Query: 315 PSSIGQLTNMRTFAADHNYLQQLPPEIGNWKNITVLFLHCNKLETLPEEMGDMQKLKVIN 374
           P  I + +++      HN L+ LP  I   KN+ VL    N++  LP+ + DM  L+V++
Sbjct: 725 PDEI-EFSSVAELVLSHNTLRTLPRTISAMKNLVVLKADHNEICVLPDALCDMTALQVLH 901

Query: 375 LSDNRLKNLPFSFTKLQQLTAMWLSDN 401
           L+DN L  LP  F +L+ L  + L +N
Sbjct: 902 LNDNLLPTLPLEFDQLKGLQDLCLHNN 982

 Score =  109 bits (272), Expect = 9e-24,   Method: Compositional matrix adjust.
 Identities = 87/331 (26%), Positives = 152/331 (45%), Gaps = 23/331 (6%)
 Frame = +2

Query: 34  LEQVPKEIFTFEKTLEELYLDANQIEELPKQLFNCQSLHKLSLPDNDLTTLPASIANLIN 93
           L  +P+ I  +   LE L L  N +E LP +  N + + +L L DN+ T++P +I +L  
Sbjct: 83  LTLIPESI-CWCSNLEILSLHKNHLERLPVEFANLRKITRLILSDNNFTSVPVAIGSLTE 259

Query: 94  LRELDVSKNGIQEFPENIKNCKVLT-----------------------IVEASVNPISKL 130
           L  L +  N + E P+ +   K LT                       I++ S N I+++
Sbjct: 260 LEALLLDGNSLHEIPQELGTLKKLTHLSLGRNAFKEFPRPACSITSLEILDLSDNKITEI 439

Query: 131 PDGFSQLLNLTQLYLNDAFLEFLPANFGRLTKLQILELRENQLKMLPKTMNRLTQLERLD 190
           P   +QLL+L +LY+    +    A    L KLQ+ +   N L  LP+ ++ L  L+ LD
Sbjct: 440 PSDIAQLLSLRELYMKKNAVSVFCAELCALQKLQMADFSNNGLLDLPEEVSVLGCLQELD 619

Query: 191 LGSNEFTEVPEVLEQLSGLREFWMDGNRLTFIPGFIGSLRQLTYLDVSKNNIEMVEEGIS 250
           L +N+F E P+    +  L +          +P                + IE       
Sbjct: 620 LSNNQFFEFPKTACSIPHLHKLVFSQQEGLKVPSL-------------PDEIEF------ 742

Query: 251 TCENLQDFLLSSNSLQQLPETIGSLKNVTTLKIDENQLMYLPDSIGGLRSIEELDCSFNE 310
              ++ + +LS N+L+ LP TI ++KN+  LK D N++  LPD++  + +++ L  + N 
Sbjct: 743 --SSVAELVLSHNTLRTLPRTISAMKNLVVLKADHNEICVLPDALCDMTALQVLHLNDNL 916

Query: 311 IEALPSSIGQLTNMRTFAADHNYLQQLPPEI 341
           +  LP    QL  ++     +N L+  P ++
Sbjct: 917 LPTLPLEFDQLKGLQDLCLHNNPLRSPPMDV 1009

 Score =  103 bits (258), Expect = 3e-22,   Method: Compositional matrix adjust.
 Identities = 76/268 (28%), Positives = 129/268 (48%), Gaps = 1/268 (0%)
 Frame = +2

Query: 171 NQLKMLPKTMNRLTQLERLDLGSNEFTEVPEVLEQLSGLREFWMDGNRLTFIPGFIGSLR 230
           N L +LP+ +  L +L+ +  GSN+ T +PE +   S L    +  N L  +P    +LR
Sbjct: 8   NCLTVLPEDIAELFELKEVYCGSNQLTLIPESICWCSNLEILSLHKNHLERLPVEFANLR 187

Query: 231 QLTYLDVSKNNIEMVEEGISTCENLQDFLLSSNSLQQLPETIGSLKNVTTLKIDENQLMY 290
           ++T L +S NN   V   I +   L+  LL  NSL ++P+ +G+LK +T L +  N    
Sbjct: 188 KITRLILSDNNFTSVPVAIGSLTELEALLLDGNSLHEIPQELGTLKKLTHLSLGRNAFKE 367

Query: 291 LPDSIGGLRSIEELDCSFNEIEALPSSIGQLTNMRTFAADHNYLQQLPPEIGNWKNITVL 350
            P     + S+E LD S N+I  +PS I QL ++R      N +     E+   + + + 
Sbjct: 368 FPRPACSITSLEILDLSDNKITEIPSDIAQLLSLRELYMKKNAVSVFCAELCALQKLQMA 547

Query: 351 FLHCNKLETLPEEMGDMQKLKVINLSDNRLKNLPFSFTKLQQLTAMWLSDNQSKPLIPLQ 410
               N L  LPEE+  +  L+ ++LS+N+    P +   +  L  +  S  +   +  L 
Sbjct: 548 DFSNNGLLDLPEEVSVLGCLQELDLSNNQFFEFPKTACSIPHLHKLVFSQQEGLKVPSLP 727

Query: 411 KETD-TETQKMVLTNYMFPQQPRTEDVM 437
            E + +   ++VL++      PRT   M
Sbjct: 728 DEIEFSSVAELVLSHNTLRTLPRTISAM 811

 Score = 80.5 bits (197), Expect = 5e-15,   Method: Compositional matrix adjust.
 Identities = 73/258 (28%), Positives = 115/258 (44%), Gaps = 2/258 (0%)
 Frame = +2

Query: 33  SLEQVPKEIFTFEKTLEELYLDANQIEELPKQLFNCQSLHKLSLPDNDLTTLPASIANLI 92
           SL ++P+E+ T +K L  L L  N  +E P+   +  SL  L L DN +T +P+ IA L+
Sbjct: 287 SLHEIPQELGTLKK-LTHLSLGRNAFKEFPRPACSITSLEILDLSDNKITEIPSDIAQLL 463

Query: 93  NLRELDVSKNGIQEFPENIKNCKVLTIVEASVNPISKLPDGFSQLLNLTQLYLNDAFLEF 152
           +LREL + KN +  F   +   + L + + S N +  LP+  S                 
Sbjct: 464 SLRELYMKKNAVSVFCAELCALQKLQMADFSNNGLLDLPEEVSV---------------- 595

Query: 153 LPANFGRLTKLQILELRENQLKMLPKTMNRLTQLERLDLGSNEFTEVPEVLEQL--SGLR 210
                  L  LQ L+L  NQ    PKT   +  L +L     E  +VP + +++  S + 
Sbjct: 596 -------LGCLQELDLSNNQFFEFPKTACSIPHLHKLVFSQQEGLKVPSLPDEIEFSSVA 754

Query: 211 EFWMDGNRLTFIPGFIGSLRQLTYLDVSKNNIEMVEEGISTCENLQDFLLSSNSLQQLPE 270
           E  +  N L  +P  I +++ L  L    N I ++ + +     LQ   L+ N L  LP 
Sbjct: 755 ELVLSHNTLRTLPRTISAMKNLVVLKADHNEICVLPDALCDMTALQVLHLNDNLLPTLPL 934

Query: 271 TIGSLKNVTTLKIDENQL 288
               LK +  L +  N L
Sbjct: 935 EFDQLKGLQDLCLHNNPL 988

 Score = 65.9 bits (159), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 42/141 (29%), Positives = 64/141 (45%)
 Frame = +2

Query: 262 SNSLQQLPETIGSLKNVTTLKIDENQLMYLPDSIGGLRSIEELDCSFNEIEALPSSIGQL 321
           +N L  LPE I  L  +  +    NQL  +P+SI    ++E L    N +E LP     L
Sbjct: 5   NNCLTVLPEDIAELFELKEVYCGSNQLTLIPESICWCSNLEILSLHKNHLERLPVEFANL 184

Query: 322 TNMRTFAADHNYLQQLPPEIGNWKNITVLFLHCNKLETLPEEMGDMQKLKVINLSDNRLK 381
             +       N    +P  IG+   +  L L  N L  +P+E+G ++KL  ++L  N  K
Sbjct: 185 RKITRLILSDNNFTSVPVAIGSLTELEALLLDGNSLHEIPQELGTLKKLTHLSLGRNAFK 364

Query: 382 NLPFSFTKLQQLTAMWLSDNQ 402
             P     +  L  + LSDN+
Sbjct: 365 EFPRPACSITSLEILDLSDNK 427

 Score = 44.3 bits (103), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 26/93 (27%), Positives = 50/93 (53%)
 Frame = +2

Query: 330 DHNYLQQLPPEIGNWKNITVLFLHCNKLETLPEEMGDMQKLKVINLSDNRLKNLPFSFTK 389
           ++N L  LP +I     +  ++   N+L  +PE +     L++++L  N L+ LP  F  
Sbjct: 2   ENNCLTVLPEDIAELFELKEVYCGSNQLTLIPESICWCSNLEILSLHKNHLERLPVEFAN 181

Query: 390 LQQLTAMWLSDNQSKPLIPLQKETDTETQKMVL 422
           L+++T + LSDN     +P+   + TE + ++L
Sbjct: 182 LRKITRLILSDNNFTS-VPVAIGSLTELEALLL 277
>09309
          Length = 1508

 Score = 79.3 bits (194), Expect = 9e-15,   Method: Compositional matrix adjust.
 Identities = 71/270 (26%), Positives = 130/270 (48%), Gaps = 28/270 (10%)
 Frame = +3

Query: 160 LTKLQILELRENQLKMLPKTMNRLTQLERLDLGSNEFTEVPEVLEQLSGLREFWMDGNRL 219
           L+ L  L++R+N+L  LP  +  L  LERLDL +N+ + +P  L  ++ L+   +DGN +
Sbjct: 15  LSTLNFLDVRDNKLAKLPDEITLLENLERLDLSNNDISMLPYSLGTINSLKSVILDGNPM 194

Query: 220 TFIPGFI---GSLRQLTYLDVSKNNIEMVEEGISTCENLQDFLLS-------SNSLQQLP 269
             I   I   G++    YL   ++ IE  E   +   + +  L +       ++ +QQ  
Sbjct: 195 KSIRRDIIMRGTMELKKYL---RSRIEEPESRPAPVTSKESVLPTGSGDTQQAHEMQQFK 365

Query: 270 ETIGSLKN----------------VTTLKIDENQLMYLPDSIGGL-RSIEELDCSFNEIE 312
               S KN                VT++ I +NQ   LP ++  L  S+ EL+  FN++ 
Sbjct: 366 TMDFSGKNANAVPADMWEKAQEAAVTSVNISKNQFTQLPSNLFLLVNSLTELNMGFNKLT 545

Query: 313 ALPSSIGQLTNMRTFAADHNYLQQLPPEIGNWKNITVLFLHCNKLETLPEEMGDMQKLKV 372
            L   IG    +      +N L  LP E+ + + +  + L CN+   +P+ + +++KL++
Sbjct: 546 GLSPDIGLFLKLTCLDLRNNGLSSLPAELCSMQALREVILSCNRFTEIPQALYELKKLEI 725

Query: 373 INLSDNRLKNL-PFSFTKLQQLTAMWLSDN 401
           + L+DN++  + P    +L  L  + L +N
Sbjct: 726 LFLNDNQVSTIEPSGLQRLGVLATLDLQNN 815

 Score = 64.3 bits (155), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 76/310 (24%), Positives = 131/310 (42%), Gaps = 24/310 (7%)
 Frame = +3

Query: 70  SLHKLSLPDNDLTTLPASIANLINLRELDVSKNGIQEFPENIKNCKVLTIVEASVNPISK 129
           +L+ L + DN L  LP  I  L NL  LD+S N I   P ++     L  V    NP+  
Sbjct: 21  TLNFLDVRDNKLAKLPDEITLLENLERLDLSNNDISMLPYSLGTINSLKSVILDGNPMKS 200

Query: 130 LP-DGFSQLLNLTQLYLNDAFLE-------------FLPANFG------RLTKLQILELR 169
           +  D   +     + YL     E              LP   G       + + + ++  
Sbjct: 201 IRRDIIMRGTMELKKYLRSRIEEPESRPAPVTSKESVLPTGSGDTQQAHEMQQFKTMDFS 380

Query: 170 ENQLKMLPKTMNRLTQ---LERLDLGSNEFTEVPEVLEQL-SGLREFWMDGNRLTFIPGF 225
                 +P  M    Q   +  +++  N+FT++P  L  L + L E  M  N+LT +   
Sbjct: 381 GKNANAVPADMWEKAQEAAVTSVNISKNQFTQLPSNLFLLVNSLTELNMGFNKLTGLSPD 560

Query: 226 IGSLRQLTYLDVSKNNIEMVEEGISTCENLQDFLLSSNSLQQLPETIGSLKNVTTLKIDE 285
           IG   +LT LD+  N +  +   + + + L++ +LS N   ++P+ +  LK +  L +++
Sbjct: 561 IGLFLKLTCLDLRNNGLSSLPAELCSMQALREVILSCNRFTEIPQALYELKKLEILFLND 740

Query: 286 NQLMYLPDSIGGLRSIEELDCSFNEIEALPSSIGQLTNMRTFAADHNYLQQLPPEIGNWK 345
           NQ+           +IE            PS + +L  + T    +N + Q+PPE+GN  
Sbjct: 741 NQV----------STIE------------PSGLQRLGVLATLDLQNNNISQVPPELGNCT 854

Query: 346 NITVLFLHCN 355
           ++  L L  N
Sbjct: 855 SLRSLQLGGN 884

 Score = 63.5 bits (153), Expect = 5e-10,   Method: Compositional matrix adjust.
 Identities = 55/202 (27%), Positives = 89/202 (44%), Gaps = 4/202 (1%)
 Frame = +3

Query: 20  EEETVTTLDYSHCSLEQVPKEIF--TFEKTLEELYLDANQIEELPKQLFN-CQSLHKLSL 76
           E +   T+D+S  +   VP +++    E  +  + +  NQ  +LP  LF    SL +L++
Sbjct: 348 EMQQFKTMDFSGKNANAVPADMWEKAQEAAVTSVNISKNQFTQLPSNLFLLVNSLTELNM 527

Query: 77  PDNDLTTLPASIANLINLRELDVSKNGIQEFPENIKNCKVLTIVEASVNPISKLPDGFSQ 136
             N LT L   I   + L  LD+  NG+   P  + + + L  V  S N  +++P    +
Sbjct: 528 GFNKLTGLSPDIGLFLKLTCLDLRNNGLSSLPAELCSMQALREVILSCNRFTEIPQALYE 707

Query: 137 LLNLTQLYLNDAFLEFLPANFGRLTKLQILELRENQLKML-PKTMNRLTQLERLDLGSNE 195
           L                        KL+IL L +NQ+  + P  + RL  L  LDL +N 
Sbjct: 708 L-----------------------KKLEILFLNDNQVSTIEPSGLQRLGVLATLDLQNNN 818

Query: 196 FTEVPEVLEQLSGLREFWMDGN 217
            ++VP  L   + LR   + GN
Sbjct: 819 ISQVPPELGNCTSLRSLQLGGN 884

 Score = 60.1 bits (144), Expect = 7e-09,   Method: Compositional matrix adjust.
 Identities = 45/155 (29%), Positives = 77/155 (49%), Gaps = 1/155 (0%)
 Frame = +3

Query: 18  RGEEETVTTLDYSHCSLEQVPKEIFTFEKTLEELYLDANQIEELPKQLFNCQSLHKLSLP 77
           + +E  VT+++ S     Q+P  +F    +L EL +  N++  L   +     L  L L 
Sbjct: 420 KAQEAAVTSVNISKNQFTQLPSNLFLLVNSLTELNMGFNKLTGLSPDIGLFLKLTCLDLR 599

Query: 78  DNDLTTLPASIANLINLRELDVSKNGIQEFPENIKNCKVLTIVEASVNPISKL-PDGFSQ 136
           +N L++LPA + ++  LRE+ +S N   E P+ +   K L I+  + N +S + P G  +
Sbjct: 600 NNGLSSLPAELCSMQALREVILSCNRFTEIPQALYELKKLEILFLNDNQVSTIEPSGLQR 779

Query: 137 LLNLTQLYLNDAFLEFLPANFGRLTKLQILELREN 171
           L  L  L L +  +  +P   G  T L+ L+L  N
Sbjct: 780 LGVLATLDLQNNNISQVPPELGNCTSLRSLQLGGN 884
>19531
          Length = 415

 Score = 71.2 bits (173), Expect = 3e-12,   Method: Compositional matrix adjust.
 Identities = 38/123 (30%), Positives = 76/123 (61%)
 Frame = -2

Query: 254 NLQDFLLSSNSLQQLPETIGSLKNVTTLKIDENQLMYLPDSIGGLRSIEELDCSFNEIEA 313
           +L   +L+SN+L  L E +  L  +T L + +N L  LP+++G L ++++L+ S N++  
Sbjct: 369 DLTKLILASNALTSLGEGLAQLPALTVLDVHDNHLQSLPNALGELENLQKLNISHNQLVE 190

Query: 314 LPSSIGQLTNMRTFAADHNYLQQLPPEIGNWKNITVLFLHCNKLETLPEEMGDMQKLKVI 373
           LPS IG+L+N+ +  A+HN L  + P++ + + +  L +  N L  LP+ +G + ++  +
Sbjct: 189 LPSCIGRLSNLVSVHAEHNKLTLICPDLVDCRKLEELDVSNNDLAELPKYIGLLSRMFRL 10

Query: 374 NLS 376
           N++
Sbjct: 9   NVA 1

 Score = 64.7 bits (156), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 39/118 (33%), Positives = 62/118 (52%)
 Frame = -2

Query: 207 SGLREFWMDGNRLTFIPGFIGSLRQLTYLDVSKNNIEMVEEGISTCENLQDFLLSSNSLQ 266
           + L +  +  N LT +   +  L  LT LDV  N+++ +   +   ENLQ   +S N L 
Sbjct: 372 TDLTKLILASNALTSLGEGLAQLPALTVLDVHDNHLQSLPNALGELENLQKLNISHNQLV 193

Query: 267 QLPETIGSLKNVTTLKIDENQLMYLPDSIGGLRSIEELDCSFNEIEALPSSIGQLTNM 324
           +LP  IG L N+ ++  + N+L  +   +   R +EELD S N++  LP  IG L+ M
Sbjct: 192 ELPSCIGRLSNLVSVHAEHNKLTLICPDLVDCRKLEELDVSNNDLAELPKYIGLLSRM 19

 Score = 56.6 bits (135), Expect = 6e-08,   Method: Compositional matrix adjust.
 Identities = 33/108 (30%), Positives = 61/108 (56%)
 Frame = -2

Query: 277 NVTTLKIDENQLMYLPDSIGGLRSIEELDCSFNEIEALPSSIGQLTNMRTFAADHNYLQQ 336
           ++T L +  N L  L + +  L ++  LD   N +++LP+++G+L N++     HN L +
Sbjct: 369 DLTKLILASNALTSLGEGLAQLPALTVLDVHDNHLQSLPNALGELENLQKLNISHNQLVE 190

Query: 337 LPPEIGNWKNITVLFLHCNKLETLPEEMGDMQKLKVINLSDNRLKNLP 384
           LP  IG   N+  +    NKL  +  ++ D +KL+ +++S+N L  LP
Sbjct: 189 LPSCIGRLSNLVSVHAEHNKLTLICPDLVDCRKLEELDVSNNDLAELP 46

 Score = 55.5 bits (132), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 34/111 (30%), Positives = 59/111 (53%)
 Frame = -2

Query: 132 DGFSQLLNLTQLYLNDAFLEFLPANFGRLTKLQILELRENQLKMLPKTMNRLTQLERLDL 191
           D + +  +LT+L L    L  L     +L  L +L++ +N L+ LP  +  L  L++L++
Sbjct: 390 DRWWEQTDLTKLILASNALTSLGEGLAQLPALTVLDVHDNHLQSLPNALGELENLQKLNI 211

Query: 192 GSNEFTEVPEVLEQLSGLREFWMDGNRLTFIPGFIGSLRQLTYLDVSKNNI 242
             N+  E+P  + +LS L     + N+LT I   +   R+L  LDVS N++
Sbjct: 210 SHNQLVELPSCIGRLSNLVSVHAEHNKLTLICPDLVDCRKLEELDVSNNDL 58

 Score = 37.4 bits (85), Expect = 0.042,   Method: Compositional matrix adjust.
 Identities = 27/89 (30%), Positives = 43/89 (48%)
 Frame = -2

Query: 23  TVTTLDYSHCSLEQVPKEIFTFEKTLEELYLDANQIEELPKQLFNCQSLHKLSLPDNDLT 82
            +T LD     L+ +P  +   E  L++L +  NQ+ ELP  +    +L  +    N LT
Sbjct: 300 ALTVLDVHDNHLQSLPNALGELEN-LQKLNISHNQLVELPSCIGRLSNLVSVHAEHNKLT 124

Query: 83  TLPASIANLINLRELDVSKNGIQEFPENI 111
            +   + +   L ELDVS N + E P+ I
Sbjct: 123 LICPDLVDCRKLEELDVSNNDLAELPKYI 37
>20480
          Length = 638

 Score = 67.4 bits (163), Expect = 4e-11,   Method: Compositional matrix adjust.
 Identities = 37/114 (32%), Positives = 64/114 (56%)
 Frame = -1

Query: 231 QLTYLDVSKNNIEMVEEGISTCENLQDFLLSSNSLQQLPETIGSLKNVTTLKIDENQLMY 290
           +L  LD+S N+IE V   +S  + L+  +L+ N ++ +P +IG +K +  L ++EN+L  
Sbjct: 431 KLQILDLSNNDIEAVSSELSGLQTLRQLILNGNKMEAIPGSIGFMKELRVLGVNENRLRE 252

Query: 291 LPDSIGGLRSIEELDCSFNEIEALPSSIGQLTNMRTFAADHNYLQQLPPEIGNW 344
           +PDSIG L ++E L    N +E L   + +L  +       N++  LP E+ N 
Sbjct: 251 VPDSIGNLENLEILGLERNCLEFLNPVVCKLEGLLRLGLSGNHMTNLPREVENL 90

 Score = 63.2 bits (152), Expect = 7e-10,   Method: Compositional matrix adjust.
 Identities = 39/124 (31%), Positives = 68/124 (54%)
 Frame = -1

Query: 172 QLKMLPKTMNRLTQLERLDLGSNEFTEVPEVLEQLSGLREFWMDGNRLTFIPGFIGSLRQ 231
           QL+ + +++ RL +L+ LDL +N+   V   L  L  LR+  ++GN++  IPG IG +++
Sbjct: 470 QLQAVNRSVFRLPKLQILDLSNNDIEAVSSELSGLQTLRQLILNGNKMEAIPGSIGFMKE 291

Query: 232 LTYLDVSKNNIEMVEEGISTCENLQDFLLSSNSLQQLPETIGSLKNVTTLKIDENQLMYL 291
           L  L V++N +  V + I   ENL+   L  N L+ L   +  L+ +  L +  N +  L
Sbjct: 290 LRVLGVNENRLREVPDSIGNLENLEILGLERNCLEFLNPVVCKLEGLLRLGLSGNHMTNL 111

Query: 292 PDSI 295
           P  +
Sbjct: 110 PREV 99

 Score = 62.8 bits (151), Expect = 9e-10,   Method: Compositional matrix adjust.
 Identities = 36/120 (30%), Positives = 66/120 (55%)
 Frame = -1

Query: 265 LQQLPETIGSLKNVTTLKIDENQLMYLPDSIGGLRSIEELDCSFNEIEALPSSIGQLTNM 324
           LQ +  ++  L  +  L +  N +  +   + GL+++ +L  + N++EA+P SIG +  +
Sbjct: 467 LQAVNRSVFRLPKLQILDLSNNDIEAVSSELSGLQTLRQLILNGNKMEAIPGSIGFMKEL 288

Query: 325 RTFAADHNYLQQLPPEIGNWKNITVLFLHCNKLETLPEEMGDMQKLKVINLSDNRLKNLP 384
           R    + N L+++P  IGN +N+ +L L  N LE L   +  ++ L  + LS N + NLP
Sbjct: 287 RVLGVNENRLREVPDSIGNLENLEILGLERNCLEFLNPVVCKLEGLLRLGLSGNHMTNLP 108

 Score = 48.9 bits (115), Expect(2) = 4e-08,   Method: Compositional matrix adjust.
 Identities = 31/131 (23%), Positives = 71/131 (54%)
 Frame = -1

Query: 310 EIEALPSSIGQLTNMRTFAADHNYLQQLPPEIGNWKNITVLFLHCNKLETLPEEMGDMQK 369
           +++A+  S+ +L  ++     +N ++ +  E+   + +  L L+ NK+E +P  +G M++
Sbjct: 470 QLQAVNRSVFRLPKLQILDLSNNDIEAVSSELSGLQTLRQLILNGNKMEAIPGSIGFMKE 291

Query: 370 LKVINLSDNRLKNLPFSFTKLQQLTAMWLSDNQSKPLIPLQKETDTETQKMVLTNYMFPQ 429
           L+V+ +++NRL+ +P S   L+ L  + L  N  + L P+  + +   +  +  N+M   
Sbjct: 290 LRVLGVNENRLREVPDSIGNLENLEILGLERNCLEFLNPVVCKLEGLLRLGLSGNHM-TN 114

Query: 430 QPRTEDVMFIS 440
            PR  + + +S
Sbjct: 113 LPREVENLILS 81

 Score = 28.1 bits (61), Expect(2) = 4e-08,   Method: Compositional matrix adjust.
 Identities = 12/40 (30%), Positives = 24/40 (60%)
 Frame = -2

Query: 265 LQQLPETIGSLKNVTTLKIDENQLMYLPDSIGGLRSIEEL 304
           L Q+P+ +  L+ +  L +  N++  +PD+I  L ++E L
Sbjct: 604 LTQMPDPVFDLEQLVCLSLSNNKITEIPDAISHLDNLEVL 485

 Score = 47.0 bits (110), Expect(2) = 8e-06,   Method: Compositional matrix adjust.
 Identities = 36/128 (28%), Positives = 63/128 (49%)
 Frame = -1

Query: 57  QIEELPKQLFNCQSLHKLSLPDNDLTTLPASIANLINLRELDVSKNGIQEFPENIKNCKV 116
           Q++ + + +F    L  L L +ND+  + + ++ L  LR+L ++ N ++  P +I   K 
Sbjct: 470 QLQAVNRSVFRLPKLQILDLSNNDIEAVSSELSGLQTLRQLILNGNKMEAIPGSIGFMKE 291

Query: 117 LTIVEASVNPISKLPDGFSQLLNLTQLYLNDAFLEFLPANFGRLTKLQILELRENQLKML 176
           L ++  + N + ++PD    L NL  L L    LEFL     +L  L  L L  N +  L
Sbjct: 290 LRVLGVNENRLREVPDSIGNLENLEILGLERNCLEFLNPVVCKLEGLLRLGLSGNHMTNL 111

Query: 177 PKTMNRLT 184
           P+ +  L 
Sbjct: 110 PREVENLI 87

 Score = 22.3 bits (46), Expect(2) = 8e-06,   Method: Compositional matrix adjust.
 Identities = 13/26 (50%), Positives = 15/26 (57%)
 Frame = -2

Query: 186 LERLDLGSNEFTEVPEVLEQLSGLRE 211
           LE+L L  NEF  VP  +  L  LRE
Sbjct: 82  LEQLLLDDNEFDFVPVQVYWLEDLRE 5
>05532
          Length = 1607

 Score = 51.2 bits (121), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 34/106 (32%), Positives = 55/106 (51%), Gaps = 4/106 (3%)
 Frame = +3

Query: 159 RLTKLQILELRENQLKMLPKTMNRLTQLERLDLGSNEFTEVPEVLEQLSGLREFWMDGNR 218
           R   L  L L +N+L  +   +++L  L  LDL SN+ + +P  +  L+ LRE  +  N+
Sbjct: 171 RFQHLTCLYLNDNRLDHISPHVSQLHHLVCLDLSSNQLSSLPSEIGDLTELRELLLYNNQ 350

Query: 219 LTFIPGFIGSLRQLTYLDVSKNNIEM----VEEGISTCENLQDFLL 260
           LT +P  +G L QL  LD+  N +        +G++   +L  FLL
Sbjct: 351 LTSLPFELGRLFQLQNLDIKGNPLSQDYMHFYQGMNGTNDLLSFLL 488

 Score = 48.9 bits (115), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 36/102 (35%), Positives = 54/102 (52%), Gaps = 5/102 (4%)
 Frame = +3

Query: 139 NLTQLYLNDAFLEFLPANFGRLTKLQILELRENQLKMLPKTMNRLTQLERLDLGSNEFTE 198
           +LT LYLND  L+ +  +  +L  L  L+L  NQL  LP  +  LT+L  L L +N+ T 
Sbjct: 180 HLTCLYLNDNRLDHISPHVSQLHHLVCLDLSSNQLSSLPSEIGDLTELRELLLYNNQLTS 359

Query: 199 VPEVLEQLSGLREFWMDGNRLT-----FIPGFIGSLRQLTYL 235
           +P  L +L  L+   + GN L+     F  G  G+   L++L
Sbjct: 360 LPFELGRLFQLQNLDIKGNPLSQDYMHFYQGMNGTNDLLSFL 485

 Score = 46.2 bits (108), Expect = 9e-05,   Method: Compositional matrix adjust.
 Identities = 37/132 (28%), Positives = 66/132 (50%), Gaps = 1/132 (0%)
 Frame = +3

Query: 275 LKNVTTLKIDENQLMYLPDSIGGLRSIEELDCSFNEIEALPSSIGQLTNMRTFAADHNYL 334
            +++T L +++N+L ++   +  L  +  LD S N++ +LPS IG LT +R     +N L
Sbjct: 174 FQHLTCLYLNDNRLDHISPHVSQLHHLVCLDLSSNQLSSLPSEIGDLTELRELLLYNNQL 353

Query: 335 QQLPPEIGNWKNITVLFLHCNKLETLPEEMGDMQKLKVIN-LSDNRLKNLPFSFTKLQQL 393
             LP E+G    +  L +  N L    + M   Q +   N L    L N+P++ T+L   
Sbjct: 354 TSLPFELGRLFQLQNLDIKGNPLSQ--DYMHFYQGMNGTNDLLSFLLDNMPYTSTQLPHR 527

Query: 394 TAMWLSDNQSKP 405
              W+ + + +P
Sbjct: 528 E--WMKNEEEEP 557

 Score = 45.4 bits (106), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 42/141 (29%), Positives = 66/141 (46%)
 Frame = +3

Query: 16  CLRGEEETVTTLDYSHCSLEQVPKEIFTFEKTLEELYLDANQIEELPKQLFNCQSLHKLS 75
           CL G+     T+  S   +  +  E+F F+  L  LYL+ N+++ +   +     L  L 
Sbjct: 93  CLGGKPTAWHTITISGL-VRNISPELFRFQH-LTCLYLNDNRLDHISPHVSQLHHLVCLD 266

Query: 76  LPDNDLTTLPASIANLINLRELDVSKNGIQEFPENIKNCKVLTIVEASVNPISKLPDGFS 135
           L  N L++LP+ I +L  LREL +  N +   P  +     L  ++   NP+S+    F 
Sbjct: 267 LSSNQLSSLPSEIGDLTELRELLLYNNQLTSLPFELGRLFQLQNLDIKGNPLSQDYMHFY 446

Query: 136 QLLNLTQLYLNDAFLEFLPAN 156
           Q +N T    ND  L FL  N
Sbjct: 447 QGMNGT----ND-LLSFLLDN 494

 Score = 43.1 bits (100), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 30/82 (36%), Positives = 44/82 (53%)
 Frame = +3

Query: 117 LTIVEASVNPISKLPDGFSQLLNLTQLYLNDAFLEFLPANFGRLTKLQILELRENQLKML 176
           LT +  + N +  +    SQL +L  L L+   L  LP+  G LT+L+ L L  NQL  L
Sbjct: 183 LTCLYLNDNRLDHISPHVSQLHHLVCLDLSSNQLSSLPSEIGDLTELRELLLYNNQLTSL 362

Query: 177 PKTMNRLTQLERLDLGSNEFTE 198
           P  + RL QL+ LD+  N  ++
Sbjct: 363 PFELGRLFQLQNLDIKGNPLSQ 428

 Score = 42.7 bits (99), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 27/81 (33%), Positives = 40/81 (49%)
 Frame = +3

Query: 229 LRQLTYLDVSKNNIEMVEEGISTCENLQDFLLSSNSLQQLPETIGSLKNVTTLKIDENQL 288
            + LT L ++ N ++ +   +S   +L    LSSN L  LP  IG L  +  L +  NQL
Sbjct: 174 FQHLTCLYLNDNRLDHISPHVSQLHHLVCLDLSSNQLSSLPSEIGDLTELRELLLYNNQL 353

Query: 289 MYLPDSIGGLRSIEELDCSFN 309
             LP  +G L  ++ LD   N
Sbjct: 354 TSLPFELGRLFQLQNLDIKGN 416
>30747
          Length = 1168

 Score = 49.3 bits (116), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 55/215 (25%), Positives = 105/215 (48%), Gaps = 1/215 (0%)
 Frame = +3

Query: 204 EQLSGLREFWMDGNRLTFIPGFIGSLRQLTYLDVSKNNIEMVEEGISTCENLQDFLLSSN 263
           E    + E  + G  +T +P  +   R+L  LDVS N I  ++  +   ++L+D  L  N
Sbjct: 186 EDFYKVYEVDLHGTEITAVPD-LEKFRKLRVLDVSGNYITKIQH-LEFTQDLRDLKLYDN 359

Query: 264 SLQQLPETIGSLKNVTTLKIDENQLMYLPDSIGGLRSIEELDCSFNEIEALPSS-IGQLT 322
            + Q+ + + SLK + +L++  NQ+  L   +  L+ ++ L    N +  L ++ +    
Sbjct: 360 KVSQV-QGLESLKELCSLQLQYNQIESLGKGLNALKKLKCLRLDSNRLTKLDTNELLSCV 536

Query: 323 NMRTFAADHNYLQQLPPEIGNWKNITVLFLHCNKLETLPEEMGDMQKLKVINLSDNRLKN 382
           N+ T    +N++  L   +    N+  LF+  N ++ L  ++   +KL  ++LS NRL +
Sbjct: 537 NISTLDLSNNHITNLSA-LSYLPNLEELFVSGNSIQKLT-DLHRCKKLSELDLSRNRLVD 710

Query: 383 LPFSFTKLQQLTAMWLSDNQSKPLIPLQKETDTET 417
           +    + L  L  + +SDN+ K +  L K    ET
Sbjct: 711 IS-GISGLPALQTLDMSDNRLKSVTSLGKLKSLET 812
>19955
          Length = 634

 Score = 41.6 bits (96), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 32/107 (29%), Positives = 58/107 (54%)
 Frame = -2

Query: 182 RLTQLERLDLGSNEFTEVPEVLEQLSGLREFWMDGNRLTFIPGFIGSLRQLTYLDVSKNN 241
           R +  +RL+L   + T  P +LE    LR      N +T I   + SLR+L +LD+  N 
Sbjct: 369 RASNPDRLNLDRRKLTVCP-ILEGEDQLRLLNYQHNAITRI-NHLNSLRRLIFLDLYDNQ 196

Query: 242 IEMVEEGISTCENLQDFLLSSNSLQQLPETIGSLKNVTTLKIDENQL 288
           IE +  G+S+ ++L+  +L  N ++++ E + +L  +  L +  NQ+
Sbjct: 195 IEQI-AGLSSLKSLRVLMLGKNRIKRI-ENLDTLIKLDVLDLHGNQI 61
>20073
          Length = 582

 Score = 38.1 bits (87), Expect = 0.028,   Method: Composition-based stats.
 Identities = 20/55 (36%), Positives = 33/55 (60%), Gaps = 2/55 (3%)
 Frame = +3

Query: 1392 IFVTRVQPEGPASKL--LQPGDKIIQANGYSFINIEHGQAVSLLKTFHNAVDLII 1444
            I+++R+ P G A +L  L+ GD+++  NG S     H +AV LLK    +V L++
Sbjct: 48   IYISRIIPGGVADRLNCLKRGDQLLSVNGVSVEGEYHEKAVELLKLAQGSVRLVV 212
>01502
          Length = 1949

 Score = 36.6 bits (83), Expect = 0.068,   Method: Composition-based stats.
 Identities = 20/47 (42%), Positives = 28/47 (59%), Gaps = 1/47 (2%)
 Frame = +1

Query: 1389 DDGIFVTRVQPEGPASKL-LQPGDKIIQANGYSFINIEHGQAVSLLK 1434
            D GI+VT +    PA++  LQ  DKI+Q NG  F  + H QAV  ++
Sbjct: 28   DKGIYVTFIYENSPAARCGLQLHDKILQLNGKDFTVVTHKQAVENIR 168
>02951
          Length = 1076

 Score = 36.6 bits (83), Expect = 0.075,   Method: Composition-based stats.
 Identities = 20/47 (42%), Positives = 28/47 (59%), Gaps = 1/47 (2%)
 Frame = +2

Query: 1389 DDGIFVTRVQPEGPASKL-LQPGDKIIQANGYSFINIEHGQAVSLLK 1434
            D GI+VT +    PA++  LQ  DKI+Q NG  F  + H QAV  ++
Sbjct: 14   DKGIYVTFIYENSPAARCGLQLHDKILQLNGKDFTVVTHKQAVENIR 154
>29705
          Length = 674

 Score = 35.8 bits (81), Expect = 0.15,   Method: Compositional matrix adjust.
 Identities = 20/66 (30%), Positives = 37/66 (56%), Gaps = 2/66 (3%)
 Frame = -1

Query: 1383 NPFRPDDDGIFVTRVQPEGPASK--LLQPGDKIIQANGYSFINIEHGQAVSLLKTFHNAV 1440
            N   P D+GIF+T+V   G A +   +   D+++  N ++  ++ H +AV+ LK+  + V
Sbjct: 386  NQHIPGDNGIFITKVIEGGSAEQDGRIAVMDRLLAVNEHNLEDVTHEEAVAALKSTGDVV 207

Query: 1441 DLIIVR 1446
             L I +
Sbjct: 206  RLTIAK 189
>00779
          Length = 1185

 Score = 34.7 bits (78), Expect = 0.27,   Method: Composition-based stats.
 Identities = 16/29 (55%), Positives = 20/29 (68%)
 Frame = -3

Query: 1046 LAPARHGEMWAISPNDRLVPAVTRTTIQR 1074
            L+PARHG     SP  RL+PA++RTT  R
Sbjct: 985  LSPARHGYGSCTSPRSRLLPALSRTTPPR 899
>26556
          Length = 513

 Score = 30.0 bits (66), Expect = 6.8,   Method: Composition-based stats.
 Identities = 16/36 (44%), Positives = 24/36 (66%)
 Frame = +2

Query: 1411 DKIIQANGYSFINIEHGQAVSLLKTFHNAVDLIIVR 1446
            DKI+Q N   F +I+H  AV++LKT    V+L++ R
Sbjct: 2    DKILQVNHIDFRHIDHNTAVNILKT-SATVELLVER 106
>17298
          Length = 476

 Score = 30.0 bits (66), Expect = 6.8,   Method: Compositional matrix adjust.
 Identities = 24/74 (32%), Positives = 38/74 (51%), Gaps = 2/74 (2%)
 Frame = +3

Query: 10  RLVP--CRCLRGEEETVTTLDYSHCSLEQVPKEIFTFEKTLEELYLDANQIEELPKQLFN 67
           R+VP   +CL G +     +  ++ ++  VP ++ +    L  L L  NQIEELP +L  
Sbjct: 210 RMVPVLAKCLTGSD-----IIANNNAITDVPADLSSLPH-LNCLNLADNQIEELPNELCE 371

Query: 68  CQSLHKLSLPDNDL 81
           C  L +L L  N +
Sbjct: 372 CTRLKELKLSGNKI 413
>20775
          Length = 1020

 Score = 29.6 bits (65), Expect = 8.5,   Method: Compositional matrix adjust.
 Identities = 35/129 (27%), Positives = 59/129 (45%), Gaps = 7/129 (5%)
 Frame = -3

Query: 281 LKIDENQLMYLPDSIGGLRSIEELDCSFNEIEALPSSIGQLTNMRTFAADHNYLQQLPPE 340
           L +  N L  LPD+      I+ L    N   ALP ++ ++ + R      + L     +
Sbjct: 574 LDLSGNNLSTLPDNFLNGEIIDSLILKNNNFTALPVALTKVEHXRRLDVSFSALVSFSFD 395

Query: 341 I-GNWKNITVLFLHCNKL---ETLPE-EMGDMQKLKVINLSDNRLKNL--PFSFTKLQQL 393
           I  N   + ++ +  NKL    T+ E   G M   K +NL+ N +  +   F F+++ +L
Sbjct: 394 ILENVSGLEMVDMSSNKLLYASTVGESSAGVMLGXKELNLASNAIDRIEDGF-FSRMDKL 218

Query: 394 TAMWLSDNQ 402
           T + LSDN 
Sbjct: 217 TTLNLSDNH 191
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|10946890|ref|NP_067458.1| peroxisomal biogenesis
factor 5-like [Mus musculus]
         (615 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

28154                                                                 139   2e-33
17595                                                                  30   3.9  
10994                                                                  29   4.6  
13793                                                                  28   7.9  
>28154
          Length = 374

 Score =  139 bits (351), Expect = 2e-33,   Method: Compositional matrix adjust.
 Identities = 68/115 (59%), Positives = 85/115 (73%), Gaps = 2/115 (1%)
 Frame = +1

Query: 434 SKSPVDSSVLEGVKELYLEAAHQNG--DMIDPDLQTGLGVLFHLSGEFNRAIDAFNAALT 491
           + S + S+  E V+ LYL A       + +D D+Q  LGVLF+LSGE+N+A+D F AAL 
Sbjct: 1   TSSFMTSTEYEEVQNLYLSAVQMAAPQESVDADVQCNLGVLFNLSGEYNKAVDCFQAALQ 180

Query: 492 VRPEDYSLWNRLGATLANGDRSEEAVEAYTRALEIQPGFIRSRYNLGISCINLGA 546
            RP+D  LWN+LGATLANG RSEEAV+AY  AL++ PGFIRSRYNLGI+CINLG 
Sbjct: 181 ARPKDALLWNKLGATLANGGRSEEAVDAYHNALQLSPGFIRSRYNLGIACINLGC 345
>17595
          Length = 483

 Score = 29.6 bits (65), Expect = 3.9,   Method: Compositional matrix adjust.
 Identities = 9/30 (30%), Positives = 21/30 (70%)
 Frame = -2

Query: 463 PDLQTGLGVLFHLSGEFNRAIDAFNAALTV 492
           PDL    G++FH +G++ +A+ ++  A+++
Sbjct: 296 PDLYNFYGIVFHKTGQYEQAVASYERAVSL 207
>10994
          Length = 2182

 Score = 29.3 bits (64), Expect = 4.6,   Method: Compositional matrix adjust.
 Identities = 20/75 (26%), Positives = 35/75 (46%), Gaps = 4/75 (5%)
 Frame = -3

Query: 356  GITQAENENEQAAIVALQRCLELQPNNLKALMALAVSYTNTSHQQDACEALKNWIKQNPK 415
            G+   +      AI  L   L++ P + +AL+A    Y N +    A E  +  ++ +PK
Sbjct: 1634 GVEMVKKGQHLEAIQHLNLALKIDPLHTEALVARGAVYANNASYGKAIEDFEKALEGDPK 1455

Query: 416  Y----KYLVKNKKGS 426
            +    KYL++ K  S
Sbjct: 1454 HVNAKKYLMETKIAS 1410
>13793
          Length = 754

 Score = 28.5 bits (62), Expect = 7.9,   Method: Compositional matrix adjust.
 Identities = 12/31 (38%), Positives = 19/31 (61%)
 Frame = +1

Query: 469 LGVLFHLSGEFNRAIDAFNAALTVRPEDYSL 499
           LGVL+H  G+ ++A  A+  AL   P D ++
Sbjct: 439 LGVLYHRWGKLDQAEKAYQVALQYSPNDRTI 531
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|122939198|ref|NP_058040.2| clathrin, light
polypeptide A isoform c [Mus musculus]
         (236 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

01092                                                                  98   2e-33
05437                                                                  29   1.5  
>01092
          Length = 2587

 Score = 98.2 bits (243), Expect(2) = 2e-33,   Method: Compositional matrix adjust.
 Identities = 49/98 (50%), Positives = 59/98 (60%)
 Frame = -2

Query: 138  KAIKELEEWYARQDEQLQKTKANNRVADEAFYKQPFADLIGYVAAEEAFVNDIDESSPGT 197
            KA KE+++WY    EQLQKT+ NNR                  AAEEAF+ D DE   G 
Sbjct: 2121 KAKKEMDDWYKHHAEQLQKTQENNR------------------AAEEAFIKDRDEKVVGQ 1996

Query: 198  EWERVARLCDFNPKSSKQAKDVSRMRSVLISLKQAPLV 235
             WE++ RLC+FNP  SK  KDV RMRS+L+ LKQ PLV
Sbjct: 1995 AWEKITRLCEFNPXHSKTTKDVGRMRSILLQLKQTPLV 1882

 Score = 61.6 bits (148), Expect(2) = 2e-33,   Method: Compositional matrix adjust.
 Identities = 42/124 (33%), Positives = 65/124 (52%), Gaps = 14/124 (11%)
 Frame = -1

Query: 30   DPAAAFLAQQESEIAGIEN------------DEAFAILDXXXXXXXXXXXX--XXXXDAV 75
            DPAA FLA++++E+A IE             D+ F +L                   DA 
Sbjct: 2476 DPAADFLAREQTELADIEGFGASEPLQNPVSDDGFGLLGGEEATPAGPLGDFDQLTSDAT 2297

Query: 76   DGVMNGEYYQESNGPTDSYAAISEVDRLQSEPESIRKWREEQTERLEALDANSRKQEAEW 135
              ++     +++NGP+D+Y+AIS+ D +++EPE IR WREE T+RL   D    K + EW
Sbjct: 2296 PDIVE----EQTNGPSDAYSAISQQDTVRTEPEKIRIWREENTQRLTKKDEAEEKDKEEW 2129

Query: 136  KEKA 139
            + K+
Sbjct: 2128 RLKS 2117
>05437
          Length = 1102

 Score = 29.3 bits (64), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 26/95 (27%), Positives = 42/95 (44%), Gaps = 10/95 (10%)
 Frame = -2

Query: 96  AISEVDRLQSEPESIR---------KWREEQTERLEALDANSRKQEAEWKEKAIKELE-E 145
            +SEV     +P S+R         K R E+     A  A+ RKQ  + K K +KEL+ E
Sbjct: 375 TVSEVRAPSGQPPSLRTASGAPPRKKMRLEEKAPPNAEVASYRKQLVDMKHKQMKELKSE 196

Query: 146 WYARQDEQLQKTKANNRVADEAFYKQPFADLIGYV 180
           ++    E        N +   A+ K+P   L+ ++
Sbjct: 195 YFENLTEMFFLQNGQNLMDYHAWKKRPTPQLVSFL 91
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|13385268|ref|NP_080073.1| cytochrome b-5 [Mus
musculus]
         (134 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

03125                                                                 137   2e-33
01993                                                                 113   2e-26
26857                                                                  60   2e-10
28028                                                                  27   3.0  
12609                                                                  27   3.2  
29465                                                                  27   3.2  
04481                                                                  25   7.6  
>03125
          Length = 1844

 Score =  137 bits (344), Expect = 2e-33,   Method: Compositional matrix adjust.
 Identities = 70/130 (53%), Positives = 91/130 (70%), Gaps = 1/130 (0%)
 Frame = -3

Query: 4    QSDKDVKYYTLEEIQKHKDSKSTWVILHHKVYDLTKFLEEHPGGEEVLREQAGGDATENF 63
            Q  +  K +   E+++H DSKS W+I+H++VYD+TKFL+EHPGGEEVL EQAG  ATE F
Sbjct: 1806 QHGQRKKVFRASEVKQHGDSKSAWLIIHNQVYDITKFLDEHPGGEEVLLEQAGKVATEAF 1627

Query: 64   EDVGHSTDARELSKTYIIGELHPDDRSKIAKPSDTLITTVE-SNSSWWTNWVIPAISALA 122
            EDVGHSTDAR+L K Y+IG+LH DD SK     +T     E S+S+ W+ W+IP   A+ 
Sbjct: 1626 EDVGHSTDARDLMKDYLIGDLHQDDCSKQTFTKNTGPLGREVSSSANWSGWLIPLGIAVL 1447

Query: 123  VALMYRLYMA 132
             AL YR  +A
Sbjct: 1446 AALAYRFLVA 1417
>01993
          Length = 1915

 Score =  113 bits (283), Expect = 2e-26,   Method: Compositional matrix adjust.
 Identities = 51/73 (69%), Positives = 63/73 (86%)
 Frame = -2

Query: 8    DVKYYTLEEIQKHKDSKSTWVILHHKVYDLTKFLEEHPGGEEVLREQAGGDATENFEDVG 67
            +VK Y  EE+++HKDSKSTW I+ +KVYD+TKFL+EHPGGEEV+ EQAGGDAT+ FEDVG
Sbjct: 1800 EVKVYRAEEVKQHKDSKSTWFIIDNKVYDVTKFLDEHPGGEEVMLEQAGGDATQAFEDVG 1621

Query: 68   HSTDARELSKTYI 80
            HS+DAR+L K Y 
Sbjct: 1620 HSSDARDLLKDYF 1582
>26857
          Length = 425

 Score = 60.5 bits (145), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 29/72 (40%), Positives = 44/72 (61%)
 Frame = -1

Query: 13  TLEEIQKHKDSKSTWVILHHKVYDLTKFLEEHPGGEEVLREQAGGDATENFEDVGHSTDA 72
           TLEE+QKH   +  W+ L  KVY+++ +LE HPGG E L   AG DAT+ F+++    +A
Sbjct: 248 TLEELQKHNTLEDAWIALRGKVYNISPYLEYHPGGVEELMRGAGIDATQLFDEIHKWVNA 69

Query: 73  RELSKTYIIGEL 84
             + +   +G L
Sbjct: 68  ESMLEKCFVGRL 33
>28028
          Length = 447

 Score = 26.6 bits (57), Expect = 3.0,   Method: Compositional matrix adjust.
 Identities = 15/35 (42%), Positives = 20/35 (57%)
 Frame = -2

Query: 83  ELHPDDRSKIAKPSDTLITTVESNSSWWTNWVIPA 117
           ++ PD RSKI    D  IT  +S +S+  N V PA
Sbjct: 140 QISPDSRSKIGLVDDQQITLSDSRTSFTGNLV-PA 39
>12609
          Length = 406

 Score = 26.6 bits (57), Expect = 3.2,   Method: Compositional matrix adjust.
 Identities = 19/65 (29%), Positives = 29/65 (44%), Gaps = 2/65 (3%)
 Frame = +2

Query: 8  DVKYYTLEEIQK--HKDSKSTWVILHHKVYDLTKFLEEHPGGEEVLREQAGGDATENFED 65
          D+K Y LE+I    H       + L   ++ LT FL+ HP    V+ +        +FED
Sbjct: 11 DLKDYNLEKILAGIHYFRCHDHIELLATIHTLTSFLQTHPQVRLVIIDSVAFPFRHHFED 190

Query: 66 VGHST 70
          +   T
Sbjct: 191LSQRT 205
>29465
          Length = 1330

 Score = 26.6 bits (57), Expect = 3.2,   Method: Compositional matrix adjust.
 Identities = 13/37 (35%), Positives = 21/37 (56%)
 Frame = +2

Query: 18  QKHKDSKSTWVILHHKVYDLTKFLEEHPGGEEVLREQ 54
           + +KD+   W ++   +  L K L +H  GEE LRE+
Sbjct: 497 RAYKDAGEKWEVVRCVLEVLYKLLRDHEVGEEDLREE 607
>04481
          Length = 799

 Score = 25.4 bits (54), Expect = 7.6,   Method: Compositional matrix adjust.
 Identities = 9/23 (39%), Positives = 16/23 (69%)
 Frame = -2

Query: 13  TLEEIQKHKDSKSTWVILHHKVY 35
            + EI K+  +K+ W++L H+VY
Sbjct: 570 VISEIGKYIKNKNLWLVLVHRVY 502
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|21728370|ref|NP_080178.1| CDGSH iron sulfur domain 2
[Mus musculus]
         (135 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

11077                                                                 136   2e-33
06814                                                                  31   0.17 
01860                                                                  26   6.5  
01963                                                                  26   6.5  
14475                                                                  25   8.0  
04121                                                                  25   8.8  
>11077
          Length = 921

 Score =  136 bits (343), Expect = 2e-33,   Method: Compositional matrix adjust.
 Identities = 64/132 (48%), Positives = 89/132 (67%)
 Frame = -1

Query: 3   LDSVARIVKVQLPAYLKQLPVPDSITGFARLTVSDWXXXXXXXXXXXXXXXXXXXPFFPK 62
           +++++ +V+V LP YL+ +P+P SI GFA+L+  +W                    F P 
Sbjct: 825 METLSNLVRVSLPNYLRSVPIPSSIGGFAKLSSQEWLSLVPFVGTVSIIVYVTVLAFKPA 646

Query: 63  KKQQKDSLINLKIQKENPKVVNEINIEDLCLTKAAYCRCWRSKTFPACDGSHNKHNELTG 122
            K  KD ++N+K+QKE+PKVVN ++IEDL   K +YCRCWRSK FP CDG+HNKHNE T 
Sbjct: 645 PKP-KDVIVNMKVQKESPKVVNMVDIEDLG-DKISYCRCWRSKKFPLCDGAHNKHNEETN 472

Query: 123 DNVGPLILKKKE 134
           DNVGPL+L++KE
Sbjct: 471 DNVGPLVLRRKE 436
>06814
          Length = 1280

 Score = 30.8 bits (68), Expect = 0.17,   Method: Compositional matrix adjust.
 Identities = 19/55 (34%), Positives = 25/55 (45%), Gaps = 9/55 (16%)
 Frame = +1

Query: 70  LINLKIQKENPKVVNEINIEDLC-----LTKAAYCRCWRSK--TFPAC--DGSHN 115
           L N     E+  +  ++N  D+C        AAYC CWR+   T  AC  D SH 
Sbjct: 790 LFNSFFCFEDSSIFEKLNTSDMCESMVWCNHAAYCLCWRTHIPTDTACVEDSSHT 954
>01860
          Length = 1132

 Score = 25.8 bits (55), Expect = 6.5,   Method: Compositional matrix adjust.
 Identities = 11/16 (68%), Positives = 11/16 (68%)
 Frame = +1

Query: 94  TKAAYCRCWRSKTFPA 109
           TK A CRCWR KT  A
Sbjct: 106 TKTAGCRCWRRKTTGA 153
>01963
          Length = 1138

 Score = 25.8 bits (55), Expect = 6.5,   Method: Compositional matrix adjust.
 Identities = 11/16 (68%), Positives = 11/16 (68%)
 Frame = -1

Query: 94   TKAAYCRCWRSKTFPA 109
            TK A CRCWR KT  A
Sbjct: 1018 TKTAGCRCWRRKTTGA 971
>14475
          Length = 1149

 Score = 25.4 bits (54), Expect = 8.0,   Method: Compositional matrix adjust.
 Identities = 16/50 (32%), Positives = 25/50 (50%)
 Frame = -1

Query: 73  LKIQKENPKVVNEINIEDLCLTKAAYCRCWRSKTFPACDGSHNKHNELTG 122
           L I+K+N  VV    ++  CL+K   C   R ++ PAC G+  +     G
Sbjct: 261 LGIRKKNCIVVF---VDRQCLSKHFQCA*HRGESLPACAGNQARKKSYFG 121
>04121
          Length = 1871

 Score = 25.0 bits (53), Expect = 8.8,   Method: Compositional matrix adjust.
 Identities = 20/63 (31%), Positives = 27/63 (42%), Gaps = 6/63 (9%)
 Frame = -3

Query: 60  FPKKKQQKDSLINLKIQKENPKVVNEINIED------LCLTKAAYCRCWRSKTFPACDGS 113
           F  K+Q   SL+ LK  K      +  +  D      L L  +A C+ WR KTF     S
Sbjct: 612 FS*KQQNPSSLVLLKTTKPLCISFDFFSYMDGSLCDTLLLIISAVCQHWRGKTFCTY*DS 433

Query: 114 HNK 116
           H +
Sbjct: 432 HRR 424
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|71773563|ref|NP_775277.2| casein kinase 1, gamma 1
[Mus musculus]
         (459 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

18481                                                                 139   2e-33
16959                                                                 110   1e-24
32357                                                                  54   4e-21
01718                                                                  64   2e-10
30755                                                                  55   5e-08
01707                                                                  55   7e-08
18921                                                                  54   1e-07
11780                                                                  50   2e-06
09606                                                                  49   3e-06
26560                                                                  49   4e-06
29581                                                                  49   5e-06
14126                                                                  49   5e-06
21433                                                                  48   1e-05
04591                                                                  47   2e-05
26711                                                                  47   2e-05
01756                                                                  47   2e-05
27405                                                                  46   3e-05
01106                                                                  46   4e-05
03240                                                                  45   4e-05
21800                                                                  39   6e-05
11185                                                                  44   1e-04
01392                                                                  44   2e-04
19094                                                                  43   2e-04
01060                                                                  43   3e-04
04852                                                                  43   3e-04
31885                                                                  42   4e-04
14477                                                                  42   4e-04
01966                                                                  42   5e-04
21079                                                                  42   7e-04
03508                                                                  42   7e-04
26009                                                                  41   8e-04
15910                                                                  41   8e-04
00715                                                                  41   0.001
04138                                                                  40   0.003
16708                                                                  40   0.003
07940                                                                  39   0.003
19301                                                                  37   0.019
13592                                                                  37   0.019
27546                                                                  37   0.019
12786                                                                  36   0.030
31489                                                                  36   0.037
19761                                                                  36   0.041
13066                                                                  35   0.049
11404                                                                  35   0.059
14116                                                                  33   0.25 
28157                                                                  33   0.29 
17975                                                                  31   0.86 
05814                                                                  30   1.9  
37602                                                                  30   2.3  
32359                                                                  27   3.6  
18731                                                                  28   9.1  
>18481
          Length = 437

 Score =  139 bits (351), Expect = 2e-33,   Method: Compositional matrix adjust.
 Identities = 70/145 (48%), Positives = 101/145 (69%)
 Frame = -1

Query: 61  GKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLGSAGEGLPQVYYFGPCGKYNAMVLEL 120
           G N    + +A+K+E I  +   LH E + Y+Q+G    GLP +Y++G    +NA+V+EL
Sbjct: 428 GYNTQDGKDIAVKIEAIDVKHQLLHYEAKVYEQIGRH-PGLPTMYHYGTEKHFNALVMEL 252

Query: 121 LGPSLEDLFDLCDRTFTLKTVLMIAIQLLSRMEYVHSKNLIYRDVKPENFLIGRQGNKKE 180
           LGPSLE+LF +C R FTLKT+LM++ QLLSR+E++H K  I+RD+KP+NFL+G    +  
Sbjct: 251 LGPSLEELFVICKRRFTLKTILMVSDQLLSRLEFIHQKCFIHRDLKPDNFLMGL--GRHC 78

Query: 181 HVIHIIDFGLAKEYVDPETKKHIPY 205
           H ++IIDFGL+K Y D +   HIPY
Sbjct: 77  HRLYIIDFGLSKRYKDTQGTMHIPY 3
>16959
          Length = 1747

 Score =  110 bits (274), Expect = 1e-24,   Method: Compositional matrix adjust.
 Identities = 51/94 (54%), Positives = 67/94 (71%)
 Frame = -1

Query: 235  EALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRNTPIEALCENFPEEMATYLRYVR 294
            EALG++ MYF RGSLPWQGLKA T K++ ++I + K  TP+++LC++FP E + +L Y R
Sbjct: 1747 EALGYVLMYFNRGSLPWQGLKAATKKQKCERISEKKIATPVDSLCKSFPSEFSIFLNYSR 1568

Query: 295  RLDFFEKPDYEYLRTLFTDLFERKGYTFDYAYDW 328
             L F E PDY YLR LF  LF    + FDYA+DW
Sbjct: 1567 DLRFDEGPDYTYLRQLFRVLFRTYNHHFDYAFDW 1466
>32357
          Length = 625

 Score = 54.3 bits (129), Expect(3) = 4e-21,   Method: Compositional matrix adjust.
 Identities = 30/71 (42%), Positives = 45/71 (63%)
 Frame = -2

Query: 38  LMVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLGSA 97
           L+V   +R+ KKIG G+FGE+ LG +  + E VA+KLE   ++ PQL+ E + Y+ L   
Sbjct: 450 LLVNGKYRLMKKIGSGSFGEIYLGVHNTSGEEVAVKLELKNAKHPQLYYESKLYRVL-QG 274

Query: 98  GEGLPQVYYFG 108
           G G+P   +FG
Sbjct: 273 GVGIPYCRWFG 241

 Score = 46.2 bits (108), Expect(3) = 4e-21,   Method: Compositional matrix adjust.
 Identities = 19/27 (70%), Positives = 23/27 (85%)
 Frame = -1

Query: 113 YNAMVLELLGPSLEDLFDLCDRTFTLK 139
           YN MV++LLGPSLEDLF+ C R FT+K
Sbjct: 229 YNVMVMDLLGPSLEDLFNYCGRKFTMK 149

 Score = 38.9 bits (89), Expect(3) = 4e-21,   Method: Compositional matrix adjust.
 Identities = 16/32 (50%), Positives = 28/32 (87%)
 Frame = -3

Query: 139 KTVLMIAIQLLSRMEYVHSKNLIYRDVKPENF 170
           +TVLM+A Q+++R+E +++ N I+RD+KP+NF
Sbjct: 152 ETVLMLADQMINRLE-LYTTNFIHRDLKPDNF 60
>01718
          Length = 959

 Score = 63.5 bits (153), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 53/208 (25%), Positives = 96/208 (46%), Gaps = 3/208 (1%)
 Frame = +3

Query: 46  VGKKIGCGNFGELRLGKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLGSAGEGLPQVY 105
           + +KIG G F E+    +  T + +A+K+  + S    +  E +   +L  A      + 
Sbjct: 159 ICEKIGAGFFSEVFKVTHRITGQVMALKMNTMTSNRHNMLREVQLLNRLQHAN----ILR 326

Query: 106 YFGPC---GKYNAMVLELLGPSLEDLFDLCDRTFTLKTVLMIAIQLLSRMEYVHSKNLIY 162
           + G C   G+ +A+   +   +LE L +  D        + + + L   ++Y+HS   I+
Sbjct: 327 FMGVCVHEGQLHALTEYIPSGNLEQLLEKKDEELPWTQRIQLTLGLARGLDYLHSTRFIH 506

Query: 163 RDVKPENFLIGRQGNKKEHVIHIIDFGLAKEYVDPETKKHIPYREHKSLTGTARYMSINT 222
           RD+  +N LI R+ N   H + I DFGLA +  DP  K+ +P        G+  +M+   
Sbjct: 507 RDLTSKNILIRREDNHGYHAV-IADFGLATKIPDPLDKEKLPT------VGSPYWMAPEV 665

Query: 223 HLGKEQSRRDDLEALGHMFMYFLRGSLP 250
             G   + R DL ++G + M  +   +P
Sbjct: 666 LNGHFYNERADLFSVG-IIMCEITARIP 746
>30755
          Length = 1137

 Score = 55.1 bits (131), Expect = 5e-08,   Method: Compositional matrix adjust.
 Identities = 38/128 (29%), Positives = 59/128 (46%), Gaps = 1/128 (0%)
 Frame = +2

Query: 133 DRTFTLKTVLMIAIQLLSRMEYVHSKNLIYRDVKPENFLIGRQGNKKEHVIHIIDFGLAK 192
           +R FT +       +++S + Y+HS+ +IYRD+K EN L+ + G+     I + DFGL K
Sbjct: 14  ERIFTEERTRFYGAEIISALGYLHSQGIIYRDLKLENLLLDKDGH-----IKVADFGLCK 178

Query: 193 EYVDPETKKHIPY-REHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPW 251
           E         I Y R  K+  GT  Y++       +  R  D    G +    + G LP+
Sbjct: 179 E--------DITYGRTTKTFCGTPEYLAPEVLDDNDYGRAVDWWGTGVVMYEMICGRLPF 334

Query: 252 QGLKADTL 259
                D L
Sbjct: 335 YNRDHDVL 358
>01707
          Length = 757

 Score = 55.1 bits (131), Expect = 7e-08,   Method: Compositional matrix adjust.
 Identities = 61/212 (28%), Positives = 88/212 (41%), Gaps = 7/212 (3%)
 Frame = +1

Query: 49  KIGCGNFGELRLGKNLYTNEYVAIKL------EPIKSRAPQLHLEYRFYKQLGSAGEGLP 102
           KIG G++G +   +N  T++ VAIK       +P+  +      E R  KQL      L 
Sbjct: 85  KIGEGSYGVVFKCRNKETSQLVAIKKFVESEDDPLIKKIAMR--EIRMLKQLKHPN--LV 252

Query: 103 QVYYFGPCGKYNAMVLELLGPSLEDLFDLCDRTFTLKTVLMIAIQLLSRMEYVHSKNLIY 162
           ++       K   +V + +  +L +  D   R      V  I  Q L  + + H  N I+
Sbjct: 253 RLIEVFRRKKRLHLVFDYVDHTLLNELDRYPRGLPEPMVKRIIYQTLLAVNFCHQYNTIH 432

Query: 163 RDVKPENFLIGRQGNKKEHVIHIIDFGLAKEYVDPETKKHIPYREHKSLTGTARYMSINT 222
           RDVKPEN LI RQG  K     + DFG A+    P         E+     T  Y +   
Sbjct: 433 RDVKPENILITRQGQVK-----LCDFGFARILTGPGD-------EYTDYVATRWYRAPEL 576

Query: 223 HLGKEQ-SRRDDLEALGHMFMYFLRGSLPWQG 253
            +G  Q     D+ A+G +F   L G   W G
Sbjct: 577 LVGDTQYGPPVDVWAIGCVFAELLTGQALWPG 672
>18921
          Length = 697

 Score = 53.9 bits (128), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 46/179 (25%), Positives = 85/179 (47%), Gaps = 3/179 (1%)
 Frame = +2

Query: 44  FRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLGSAGEGLPQ 103
           F +  K+G G++G +    +  T + +AIK  P+ +   ++  E    +Q  S       
Sbjct: 35  FDILGKLGEGSYGSVFKSLHKETGQVLAIKQVPVDTDLQEIIKEISIMQQCDSK----YI 202

Query: 104 VYYFGPCGKYNAM--VLELLGP-SLEDLFDLCDRTFTLKTVLMIAIQLLSRMEYVHSKNL 160
           V Y+G   K   +  V+E  G  S+ D+  L ++T   + +  I    L  + Y+HS+  
Sbjct: 203 VKYYGSYFKNTDLWIVMEYCGAGSVSDIMRLRNKTLVEREIATILYYTLKGLXYLHSRRK 382

Query: 161 IYRDVKPENFLIGRQGNKKEHVIHIIDFGLAKEYVDPETKKHIPYREHKSLTGTARYMS 219
           I+RD+K  N L+  +G+ K     + DFG+A +  D   K++       ++ GT  +M+
Sbjct: 383 IHRDIKAGNILLNNEGHAK-----LADFGVAGQLTDTMAKRN-------TVIGTPYWMA 523
>11780
          Length = 1713

 Score = 49.7 bits (117), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 50/165 (30%), Positives = 72/165 (43%), Gaps = 6/165 (3%)
 Frame = +3

Query: 34  SSGVLMVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQ 93
           S G ++   +  +G+ IG G+FG++   K +Y  + VAIK    K R  Q  L      Q
Sbjct: 573 SGGWVIAXQDLEIGEAIGKGDFGDVY--KGMYRGQPVAIKQLKDKDRGEQSFL------Q 728

Query: 94  LGSAGEGLPQ---VYYFGPC-GKYNAMVLELLGPS--LEDLFDLCDRTFTLKTVLMIAIQ 147
             S    L     V   G   G+   +V E +G    +E L        T K  +  A  
Sbjct: 729 EASVMTSLRHDNLVRLIGVVLGETIFLVTEFMGKGNLVEYLRSRGRSVITKKDQINFATD 908

Query: 148 LLSRMEYVHSKNLIYRDVKPENFLIGRQGNKKEHVIHIIDFGLAK 192
             + MEY+ SK L++RD+   N L+   G  K     + DFGLAK
Sbjct: 909 TCAAMEYLESKRLVHRDLAARNVLVHDDGKAK-----VSDFGLAK 1028
>09606
          Length = 1300

 Score = 49.3 bits (116), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 55/238 (23%), Positives = 100/238 (42%), Gaps = 18/238 (7%)
 Frame = -3

Query: 43   NFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLGSAGEGLP 102
            NF + +++G G    +  G+   T  +VAI     K + P++    R    +      + 
Sbjct: 1112 NFVLYEELGKGEHSIIYKGRRKGTINFVAIHCIE-KCKRPEVTNTVRMTHDISHPN--VV 942

Query: 103  QVYYFGPCGKYNAMVLELL-GPSLEDLFDLCDRTFTLKTVLMIAIQLLSRMEYVHSKNLI 161
            Q + +     +  +V+EL  G SL D+    D      ++    I L++ + Y+HS  ++
Sbjct: 941  QFHEWYETSNHLWLVVELCTGGSLADILAQ-DHHLPETSIRDFGIHLVTGLHYIHSLGIL 765

Query: 162  YRDVKPENFLIGRQGNKKEHVIHIIDFGLAKEYVDPETKKHIPYR--------------- 206
            + D++P   L+   G     V+   DFGL+K  V+ E  + + ++               
Sbjct: 764  FHDLRPSKVLLDTSG-----VLKFADFGLSK--VEGENLEELFFKFAEAGDQWNIQSAEE 606

Query: 207  --EHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKER 262
              +    +G+  YM+     G E S   DL ALG +F     G  P+ G   D  K++
Sbjct: 605  MMKQVPTSGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFSGHPPFLGETYDITKDK 432
>26560
          Length = 398

 Score = 49.3 bits (116), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 37/119 (31%), Positives = 61/119 (51%), Gaps = 1/119 (0%)
 Frame = -1

Query: 135 TFTLKTVLMIAIQLLSRMEYVHSKNLIYRDVKPENFLIGRQGNKKEHVIHIIDFGLAKEY 194
            FT K V   A +++  +E++HS+ ++YRD+KP N L+   G+     + I D GLA ++
Sbjct: 368 VFTEKEVRFYAAEVMLGLEHMHSRFVVYRDLKPANILLDENGH-----VRISDLGLACDF 204

Query: 195 VDPETKKHIPYREHKSLTGTARYMSINTHL-GKEQSRRDDLEALGHMFMYFLRGSLPWQ 252
               +KK    R H S+ GT  YM+    + G+      D  + G M    L+G  P++
Sbjct: 203 ----SKK----RPHASV-GTHGYMAPEVLMKGQSYDSSADWFSFGCMLYKLLKGHSPFR 54
>29581
          Length = 1278

 Score = 48.9 bits (115), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 28/83 (33%), Positives = 42/83 (50%)
 Frame = -2

Query: 116  MVLELLGPSLEDLFDLCDRTFTLKTVLMIAIQLLSRMEYVHSKNLIYRDVKPENFLIGRQ 175
            +V+E     L  L D     F+   V  I +QLL  + Y+H   +I+RD+K  N L+  +
Sbjct: 1118 LVMEYCEQDLASLLDNMPAPFSESQVKCIVLQLLKGLRYLHEAFIIHRDLKVSNLLMTDK 939

Query: 176  GNKKEHVIHIIDFGLAKEYVDPE 198
            G      + I DFGLA+ Y  P+
Sbjct: 938  G-----CVKIADFGLARNYGKPQ 885
>14126
          Length = 1265

 Score = 48.9 bits (115), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 38/128 (29%), Positives = 63/128 (49%), Gaps = 4/128 (3%)
 Frame = +3

Query: 144 IAIQLLSRMEYVHSKNLIYRDVKPENFLIGRQGNKKEHVIHIIDFGLAKEYVDPETKKHI 203
           + +QLL+ ++++HS  +++RD+KP+N LI + G  K     + DFGLA+           
Sbjct: 531 LMLQLLNGVDFLHSNRIVHRDLKPQNLLISKDGRLK-----LADFGLAR----------- 662

Query: 204 PYREHKSLTG---TARYMSINTHLGKEQSRRDDLEALGHMFM-YFLRGSLPWQGLKADTL 259
            Y  H +LT    T  Y S    +  E     D+ + G +F   F R +L     + D L
Sbjct: 663 IYSFHMALTTVVVTLWYRSPEVLMQAEYGTSVDIWSCGCIFAELFTRRALFKGSSEFDQL 842

Query: 260 KERYQKIG 267
           K+ ++ IG
Sbjct: 843 KKIFEVIG 866
>21433
          Length = 590

 Score = 47.8 bits (112), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 32/104 (30%), Positives = 46/104 (44%)
 Frame = +2

Query: 147 QLLSRMEYVHSKNLIYRDVKPENFLIGRQGNKKEHVIHIIDFGLAKEYVDPETKKHIPYR 206
           QL S +EY H + +I+RD+KPEN          +  + I DFG +          H P  
Sbjct: 191 QLSSALEYCHYRKVIHRDIKPEN-----LLLGLKGDLKIADFGWS---------VHAPSS 328

Query: 207 EHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLP 250
              ++ GT  Y+      GK      DL +LG +   FL G+ P
Sbjct: 329 RRTTMCGTLDYLPPEMVEGKTHDENVDLWSLGVLCYEFLVGTPP 460
>04591
          Length = 1117

 Score = 47.0 bits (110), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 27/91 (29%), Positives = 48/91 (52%), Gaps = 3/91 (3%)
 Frame = -2

Query: 108 GPCGKYNA---MVLELLGPSLEDLFDLCDRTFTLKTVLMIAIQLLSRMEYVHSKNLIYRD 164
           GP  +Y +   ++ E     L  L +     F+L     +  QLL+ + Y+H+K +++RD
Sbjct: 999 GPYNRYKSTFYLIFEYCDYDLAGLLNNLRVKFSLADKKNLMSQLLNGLFYIHTKQILHRD 820

Query: 165 VKPENFLIGRQGNKKEHVIHIIDFGLAKEYV 195
           +K  N L+ R G     V+ + DFGL++ +V
Sbjct: 819 IKAANILLTRDG-----VLKLADFGLSRPWV 742
>26711
          Length = 405

 Score = 46.6 bits (109), Expect = 2e-05,   Method: Composition-based stats.
 Identities = 35/119 (29%), Positives = 60/119 (50%)
 Frame = -2

Query: 147 QLLSRMEYVHSKNLIYRDVKPENFLIGRQGNKKEHVIHIIDFGLAKEYVDPETKKHIPYR 206
           Q+L  +++VH++ +++ D+KP N L+   G+K + V  +IDFGLA++   P+      + 
Sbjct: 392 QVLDILQHVHAQGVVHMDLKPSNLLL--SGDKLDSV-QLIDFGLARKLYPPQET----FL 234

Query: 207 EHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQK 265
            H    GT  + S      K  S   D+  +G +    L G  P+Q   AD+  E  +K
Sbjct: 233 NH----GTPGFTSPEALDVKPISTASDVWGVGVLAYILLSGQSPFQ---ADSATESLKK 78
>01756
          Length = 1858

 Score = 46.6 bits (109), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 42/156 (26%), Positives = 68/156 (43%), Gaps = 10/156 (6%)
 Frame = -3

Query: 49   KIGCGNFGELRLGKNLYTNEYVAIK---LEPIKSRAPQLHLEYRFYKQLGSAGEGLPQVY 105
            KIG G FGE+   +   T + VA+K   ++  K   P   L      QL +    +  + 
Sbjct: 1721 KIGQGTFGEVFKARCKKTKQVVAMKKVLMDNEKEGFPITALREIKILQLLNHENVVDLIE 1542

Query: 106  YFG----PCGKYNAM---VLELLGPSLEDLFDLCDRTFTLKTVLMIAIQLLSRMEYVHSK 158
                      +Y +M   V E     L  L       F L  +  +  QL++ + Y+H  
Sbjct: 1541 ICSTKATSANRYKSMFYLVFEFCEHDLAGLLSNMSVVFNLPEIKEVMKQLMNGLYYIHRN 1362

Query: 159  NLIYRDVKPENFLIGRQGNKKEHVIHIIDFGLAKEY 194
             +++RD+K  N LI +QG     V+ + DFGLA+ +
Sbjct: 1361 KILHRDMKAANILITKQG-----VLKLADFGLARAF 1269
>27405
          Length = 532

 Score = 45.8 bits (107), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 55/178 (30%), Positives = 82/178 (46%), Gaps = 12/178 (6%)
 Frame = -3

Query: 54  NFGELRLGKNLYTNEYVAIKL---EPIKSRAPQ-LHLEYRFYKQLGSAGEGLPQVYYFGP 109
            FGE+   +   T +  A+K    + IK +  + L L  R    L S GEG P    F  
Sbjct: 530 GFGEVYGCRKADTGKMYAMKCLDKKRIKMKGGETLALNERIMLSLVSTGEGSP----FIV 363

Query: 110 CGKYNAMVLELLGPSLEDLFDLCDR--------TFTLKTVLMIAIQLLSRMEYVHSKNLI 161
           C  Y     E L   L DL +  D          FT K V   A +++  +E++HS+ ++
Sbjct: 362 CMTYAFQTPEKLCFIL-DLMNGGDLHYHLSQHGVFTEKEVRFYAAEVMLGLEHMHSRFVV 186

Query: 162 YRDVKPENFLIGRQGNKKEHVIHIIDFGLAKEYVDPETKKHIPYREHKSLTGTARYMS 219
           YRD+KP N L+   G+     + I D GLA ++    +KK    + H S+ GT  YM+
Sbjct: 185 YRDLKPANILLDENGH-----VRISDLGLACDF----SKK----KPHASV-GTHGYMA 54
>01106
          Length = 878

 Score = 45.8 bits (107), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 39/142 (27%), Positives = 66/142 (46%), Gaps = 13/142 (9%)
 Frame = +3

Query: 44  FRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPIKSRAPQLHL-EYRFYKQL-------- 94
           + V +K+G G+F  + L  +L    +VA+K+        +  L E +  K +        
Sbjct: 324 YHVIRKLGWGHFSTVWLCWDLTCKRFVALKVVKSAQHYTETALDEVKLLKCVRESDVADP 503

Query: 95  --GSAGEGLPQVYYFGPCGKYNAMVLELLGPSLEDLFDLCD-RTFTLKTVLMIAIQLLSR 151
                 + L      G  G + AMV E+LG +L  L    + +   +  V +I  Q+L  
Sbjct: 504 ARAKCVQLLDDFKISGVNGTHVAMVFEVLGYNLLKLIIRSNYQGIPIHNVKLIIRQVLEG 683

Query: 152 MEYVHSK-NLIYRDVKPENFLI 172
           + Y+H+K  +I+ D+KPEN LI
Sbjct: 684 LSYMHAKCRIIHTDIKPENILI 749
>03240
          Length = 1683

 Score = 45.4 bits (106), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 43/153 (28%), Positives = 65/153 (42%), Gaps = 5/153 (3%)
 Frame = -3

Query: 44   FRVGKKIGCGNFGELRLGKNLYTNEYVAIKL---EPIKSRAPQLHLEYRFYKQLGSAGEG 100
            F   K +G G FGE+ L +   T    A+K      +  R    H++        +  E 
Sbjct: 1285 FEKIKTLGVGAFGEVSLCRKNDTGMLYAMKTLRKSDVLKRNQVAHVKAERDILAEADNEW 1106

Query: 101  LPQVYYFGPCGKYNAMVLELLGPSLEDLFDLCDRTFTLKTVL--MIAIQLLSRMEYVHSK 158
            + ++YY      Y   V++ +     DL  L  R   L   L      +L+  +E VH  
Sbjct: 1105 VVKLYYSFQDHNYLYFVMDYVPGG--DLMGLLIRMEILDEPLARFYVAELVQAIESVHRM 932

Query: 159  NLIYRDVKPENFLIGRQGNKKEHVIHIIDFGLA 191
              I+RD+KP+N LI R G+     I + DFGL 
Sbjct: 931  GFIHRDIKPDNILIDRNGH-----IKLTDFGLC 848
>21800
          Length = 855

 Score = 39.3 bits (90), Expect(2) = 6e-05,   Method: Compositional matrix adjust.
 Identities = 26/72 (36%), Positives = 40/72 (55%), Gaps = 2/72 (2%)
 Frame = +2

Query: 108 GPCGKYNAMVLELLGPSLEDLFDLCD-RTFTLKTVLMIAIQLLSRMEYVHSK-NLIYRDV 165
           G  G +  MV E+LG +L  L    + +   +  V +I  Q+L  + Y+H+K N+I+ D+
Sbjct: 536 GVNGTHVCMVFEVLGYNLLKLIIRSNYQGIPVHNVKLIIRQVLEGLNYLHAKCNIIHTDI 715

Query: 166 KPENFLIGRQGN 177
           KPEN LI    N
Sbjct: 716 KPENILICVDDN 751

 Score = 25.0 bits (53), Expect(2) = 6e-05,   Method: Compositional matrix adjust.
 Identities = 12/41 (29%), Positives = 23/41 (56%)
 Frame = +3

Query: 44  FRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPIKSRAPQL 84
           + V +K+G G+F  + L  +L    +VA+K+  + S   +L
Sbjct: 312 YHVVRKLGWGHFSTVWLCWDLNCKRFVALKVVKVLSIIQRL 434
>11185
          Length = 473

 Score = 44.3 bits (103), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 31/122 (25%), Positives = 54/122 (44%), Gaps = 17/122 (13%)
 Frame = +1

Query: 144 IAIQLLSRMEYVHSKNLIYRDVKPENFLIGRQGNKKEHVIHIIDFGLAKEYVDPETKKHI 203
             I L++ + Y+HS  +++ D++P   L+   G     V+   DFGL+K  V+ E  + +
Sbjct: 16  FGIHLVTGLHYIHSLGILFHDLRPSKVLLDTSG-----VLKFADFGLSK--VEGENLEEL 174

Query: 204 PYREHKS-----------------LTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLR 246
            ++  ++                  +G+  YM+     G E S   DL ALG +F     
Sbjct: 175 FFKFAEAGDQWNIQSAEEMMKQVPTSGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFS 354

Query: 247 GS 248
           GS
Sbjct: 355 GS 360
>01392
          Length = 1806

 Score = 43.5 bits (101), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 38/133 (28%), Positives = 61/133 (45%), Gaps = 10/133 (7%)
 Frame = -1

Query: 131  LCDRTFTLKTVLMIAIQLLSRMEYVHSKNLIYRDVKPENFLIGRQGNKKEHV-----IHI 185
            LC+R  +L     +   +   ++++HSK + +RD+KPEN L        EH+     + I
Sbjct: 1800 LCEREASL-----VVRHIARALDFLHSKGIAHRDLKPENILC-------EHLDDVVPVKI 1657

Query: 186  IDFGLAKEYVDPETKKHIPYREHKSLTGTARYMS---INTHLGKEQS--RRDDLEALGHM 240
             DF LA            P  E  +  G+A YM+   ++  +G   S  +R DL +LG +
Sbjct: 1656 CDFDLASGISCDGDGTKTP--ELLTPVGSAEYMAPEVVDAWVGDSFSYDKRCDLWSLGII 1483

Query: 241  FMYFLRGSLPWQG 253
                L G  P+ G
Sbjct: 1482 LYIMLCGYPPFYG 1444
>19094
          Length = 898

 Score = 43.1 bits (100), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 26/96 (27%), Positives = 49/96 (51%)
 Frame = +1

Query: 124 SLEDLFDLCDRTFTLKTVLMIAIQLLSRMEYVHSKNLIYRDVKPENFLIGRQGNKKEHVI 183
           S+ D+  L ++T   + +  I    L  + Y+HS+  I+RD+K  N L+  +G+ K    
Sbjct: 13  SVSDIMRLRNKTLVEREIATILYYTLKGL*YLHSRRKIHRDIKAGNILLNNEGHAK---- 180

Query: 184 HIIDFGLAKEYVDPETKKHIPYREHKSLTGTARYMS 219
            + DFG+A +  D   K++       ++ GT  +M+
Sbjct: 181 -LADFGVAGQLTDTMAKRN-------TVIGTPYWMA 264
>01060
          Length = 1800

 Score = 42.7 bits (99), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 23/78 (29%), Positives = 41/78 (52%), Gaps = 5/78 (6%)
 Frame = +1

Query: 145 AIQLLSRMEYVHSKNLIYRDVKPENFLIGRQGNKKEHVIHIIDFGLAKEYVDP-ETKKH- 202
             Q+++ + + H + +++RD+KP+N LI   G      I I DFG+A+ +  P     H 
Sbjct: 394 VFQIVTGIXFCHQRRIVHRDLKPQNLLINHTG-----AIKIADFGMARTFALPVRAYTHE 558

Query: 203 ---IPYREHKSLTGTARY 217
              + YR  + L G ++Y
Sbjct: 559 VVTLWYRAPEILMGASKY 612
>04852
          Length = 1462

 Score = 42.7 bits (99), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 33/139 (23%), Positives = 62/139 (44%), Gaps = 3/139 (2%)
 Frame = +1

Query: 139 KTVLMIAIQLLSRMEYVHSKNLIYRDVKPENFLIGRQGNKKEHVIHIIDFGLAK--EYVD 196
           K +L  A Q+   ME++ S+  I+RD+   N L+      +EHV+ I DFGL++  +Y  
Sbjct: 325 KNLLSYAFQIARGMEFLASRKCIHRDLAARNVLV-----TEEHVLKIADFGLSRTGDYYK 489

Query: 197 PETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALG-HMFMYFLRGSLPWQGLK 255
             +   +P           ++M+         + + D+ + G  ++  F  G +P+  + 
Sbjct: 490 KRSGGRLP----------VKWMAPEALFDMRYTTKSDVWSFGVVLWEIFSLGGMPYASIP 639

Query: 256 ADTLKERYQKIGDTKRNTP 274
            + L   Y K+ D     P
Sbjct: 640 NEEL---YSKLLDDAYRMP 687
>31885
          Length = 529

 Score = 42.4 bits (98), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 25/85 (29%), Positives = 42/85 (49%)
 Frame = -2

Query: 135 TFTLKTVLMIAIQLLSRMEYVHSKNLIYRDVKPENFLIGRQGNKKEHVIHIIDFGLAKEY 194
           +F    V     QL   ++Y+ S+ +++RD+KP+N L+  QG+      H+ DF +A + 
Sbjct: 384 SFREDCVKFYLCQLALVLDYLRSQKIVHRDIKPDNILLDEQGH-----CHVTDFNIATQL 220

Query: 195 VDPETKKHIPYREHKSLTGTARYMS 219
            D E           S +GT  YM+
Sbjct: 219 EDDELA--------TSTSGTRPYMA 169
>14477
          Length = 493

 Score = 42.4 bits (98), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 39/149 (26%), Positives = 69/149 (46%), Gaps = 5/149 (3%)
 Frame = -1

Query: 49  KIGCGNFGELRLGKNLYTNEYVAIKLEPIKSRA--PQLHLEYRFYKQLGSAGEGLPQVYY 106
           K+G GNFG +  G     +  + + ++ +K+    P +  E     ++    + +  V  
Sbjct: 469 KLGAGNFGSVMKGVCRLDDREIPVAIKVLKNADLDPSVQSELIKEAEVMKKMDHMHIVRL 290

Query: 107 FGPC-GKYNAMVLEL--LGPSLEDLFDLCDRTFTLKTVLMIAIQLLSRMEYVHSKNLIYR 163
            G C G+   +VLEL  LGP   + F   ++   L  +L +  Q+   MEY+ +   ++R
Sbjct: 289 IGLCEGETMMLVLELAKLGPL--NKFLPKNKHLPLWNILELMWQVSQGMEYLEANKFVHR 116

Query: 164 DVKPENFLIGRQGNKKEHVIHIIDFGLAK 192
           D+   N L+       EH   I DFG++K
Sbjct: 115 DLAARNILLC-----DEHFAKISDFGMSK 44
>01966
          Length = 1735

 Score = 42.0 bits (97), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 17/53 (32%), Positives = 31/53 (58%)
 Frame = -1

Query: 145  AIQLLSRMEYVHSKNLIYRDVKPENFLIGRQGNKKEHVIHIIDFGLAKEYVDP 197
              Q+++ + + H + +++RD+KP+N LI   G      I I DFG+A+ +  P
Sbjct: 1390 VFQIVTGINFCHQRRIVHRDLKPQNLLINHTG-----AIKIADFGMARTFALP 1247
>21079
          Length = 878

 Score = 41.6 bits (96), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 36/139 (25%), Positives = 65/139 (46%), Gaps = 3/139 (2%)
 Frame = +1

Query: 115 AMVLELLGPSLEDLFDLC---DRTFTLKTVLMIAIQLLSRMEYVHSKNLIYRDVKPENFL 171
            +V+E +G    +LF+     D   T +  +    Q+ S + Y+H++++++ D+KPEN L
Sbjct: 52  VLVMEFVGAG--ELFERVIRDDFVLTERDCVHFVRQICSGVGYMHTQSILHLDLKPENVL 225

Query: 172 IGRQGNKKEHVIHIIDFGLAKEYVDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRR 231
                + +   I IIDFGLA+ Y         P    + L GT  +++       E +  
Sbjct: 226 CVSDNSNQ---IKIIDFGLARFYK--------PGDSLQVLFGTPEFIAPEVVNYDEINFT 372

Query: 232 DDLEALGHMFMYFLRGSLP 250
            D+ ++G +    L G  P
Sbjct: 373 TDMWSIGVICYILLSGLSP 429
>03508
          Length = 1463

 Score = 41.6 bits (96), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 20/61 (32%), Positives = 36/61 (59%)
 Frame = +1

Query: 134 RTFTLKTVLMIAIQLLSRMEYVHSKNLIYRDVKPENFLIGRQGNKKEHVIHIIDFGLAKE 193
           +TFT   +     +L+  +++ HS  +++RDVKP N +I  +  K    + +ID+GLA+ 
Sbjct: 856 QTFTDYDIRFYLYELMKALDFCHSMGIMHRDVKPHNVMIDHENKK----LRLIDWGLAEF 1023

Query: 194 Y 194
           Y
Sbjct: 1024Y 1026
>26009
          Length = 886

 Score = 41.2 bits (95), Expect = 8e-04,   Method: Compositional matrix adjust.
 Identities = 15/26 (57%), Positives = 23/26 (88%)
 Frame = +3

Query: 147 QLLSRMEYVHSKNLIYRDVKPENFLI 172
           QL+S ++++HSK L++RD+KPEN LI
Sbjct: 735 QLVSALDFMHSKQLVHRDIKPENVLI 812
>15910
          Length = 1361

 Score = 41.2 bits (95), Expect = 8e-04,   Method: Compositional matrix adjust.
 Identities = 36/149 (24%), Positives = 70/149 (46%), Gaps = 5/149 (3%)
 Frame = +2

Query: 123 PSLEDLFDLCDRT-----FTLKTVLMIAIQLLSRMEYVHSKNLIYRDVKPENFLIGRQGN 177
           P+  + ++L DR      +T K        +L  ++Y+H+  +++RD+KPEN L   +  
Sbjct: 401 PA*GEWWELFDRIVTRGQYTEKDAARAISDILHGVQYIHANGVVHRDLKPENLLY--ECM 574

Query: 178 KKEHVIHIIDFGLAKEYVDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEAL 237
             +  + + DFGL++  ++PE        +  ++ GT  Y +     G + +   D+ ++
Sbjct: 575 TDDSKLKLADFGLSR-IIEPEV-------QMSTVCGTPGYCAPEVLKGDKYTPSVDMWSV 730

Query: 238 GHMFMYFLRGSLPWQGLKADTLKERYQKI 266
           G +    L G  P     A+   E Y+KI
Sbjct: 731 GVIAYILLCGYEP---FFAENEFEMYRKI 808
>00715
          Length = 1788

 Score = 40.8 bits (94), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 41/177 (23%), Positives = 72/177 (40%), Gaps = 18/177 (10%)
 Frame = +1

Query: 116 MVLELLGP-SLEDLFDLCDRTFTLKTVLMIAIQLLSRMEYVHSKNLIYRDVKPENFLIGR 174
           + +E +GP +L+ + +   +       L +A+Q+   + Y+HS N+++ D+KP N L+ R
Sbjct: 166 LAMEYVGPLNLQTILNDHQQDIDSSMRLSLALQMARGLHYLHSINIVHLDLKPANCLLTR 345

Query: 175 QGNKKEHVIHIIDFGLAKEYVDPETKKHIPYRE-----------------HKSLTGTARY 217
                +  + I DFG   +     T   +  RE                    L GT  Y
Sbjct: 346 -----DLKLRIADFGCCHQLT--PTGLDMGEREGGMAGNELELTPVQGAWKNELAGTLAY 504

Query: 218 MSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRNTP 274
            +     G + S R D+ +LG           P++G+ A  +   YQ +    R  P
Sbjct: 505 RAPELLKGLQPSVRSDVYSLGITLWQMCTRQGPYEGVPAHAVV--YQVVSKDLRPCP 669
>04138
          Length = 800

 Score = 39.7 bits (91), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 17/44 (38%), Positives = 28/44 (63%)
 Frame = +1

Query: 151 RMEYVHSKNLIYRDVKPENFLIGRQGNKKEHVIHIIDFGLAKEY 194
           R+ Y+H   +++RD+K  N LI +QG     V+ + DFGLA+ +
Sbjct: 49  RLYYIHRNKILHRDMKAANILITKQG-----VLKLADFGLARAF 165
>16708
          Length = 1397

 Score = 39.7 bits (91), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 45/157 (28%), Positives = 60/157 (38%), Gaps = 14/157 (8%)
 Frame = -1

Query: 141  VLMIAIQLLSRMEYVHSKNLIYRDVKPENFLIGRQGNKKEHVIHIIDFGLAKEY-VDPET 199
            V  IA Q +  +E++H   +++ DVK +N L+   GN K     + D+G+A+ Y V P  
Sbjct: 1088 VCCIAGQXVCALEHIHELGVVHMDVKADNVLVDAHGNCK-----LTDYGIAQLYKVYPA- 927

Query: 200  KKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTL 259
                P   H S     R            S R   E  G    YF  G + W    A  L
Sbjct: 926  ----PTETHSSGCTNKRTFYTRPPATMTPSERFSEEGDGIGTDYFRLGQMLWTLTGAVLL 759

Query: 260  K---ERYQKIGDTKRNTP----------IEALCENFP 283
                 R  K+ D  R TP          IE LC   P
Sbjct: 758  HVWVSRPPKLPDWCR-TPESELSGMSDFIEKLCHGDP 651
>07940
          Length = 1336

 Score = 39.3 bits (90), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 21/59 (35%), Positives = 33/59 (55%)
 Frame = -3

Query: 134 RTFTLKTVLMIAIQLLSRMEYVHSKNLIYRDVKPENFLIGRQGNKKEHVIHIIDFGLAK 192
           +  T K ++  A Q+   MEY+ SK  I+RD+   N L+      +E+V+ I DFGL +
Sbjct: 362 KMLTPKDLISYAYQVARGMEYLASKQCIHRDLAARNVLVA-----EEYVLKIADFGLTR 201
>19301
          Length = 712

 Score = 36.6 bits (83), Expect = 0.019,   Method: Compositional matrix adjust.
 Identities = 20/49 (40%), Positives = 28/49 (57%)
 Frame = +2

Query: 141 VLMIAIQLLSRMEYVHSKNLIYRDVKPENFLIGRQGNKKEHVIHIIDFG 189
           VL  + Q+ S M Y+HS  +I+RD+K  N L+      K  V+ I DFG
Sbjct: 575 VLDWSKQIASGMNYLHSHKIIHRDLKSPNVLVA-----KNDVVKISDFG 706
>13592
          Length = 980

 Score = 36.6 bits (83), Expect = 0.019,   Method: Compositional matrix adjust.
 Identities = 54/215 (25%), Positives = 91/215 (42%), Gaps = 12/215 (5%)
 Frame = +2

Query: 49  KIGCGNFGELRLGKNLYTNEYVAIK---LEPIKSRA-PQLHLEYRFYKQLGSAGEGLPQ- 103
           KIG G FG++    N  T E +A+K   ++P ++RA   +  E +         EG+   
Sbjct: 5   KIGQGRFGKVYTAVNNNTGELMAMKEIAIQPGETRALKNVAEELKIL-------EGIKHK 163

Query: 104 --VYYFGPCGKYNAMVLELLGPSLEDLFDLCDRTFTLKTVLM--IAIQLLSRMEYVHSKN 159
             V Y+G       +++ +   S   L  L + T  L   L      QLLS +  +H   
Sbjct: 164 NLVRYYGIEVHREELLIFMELCSEGTLESLVELTGGLPEALSRRFTAQLLSGVAELHKHG 343

Query: 160 LIYRDVKPENFLIGRQGNKKEHVIHIIDFGLAKEYVDPETKKHIPYREHKSLTGTARYMS 219
           +++RD+K  N  +    N     + + DFG A   V  +    +P  E +   GT  YM+
Sbjct: 344 IVHRDIKTANIFLVDGSNS----LKLGDFGSA---VKIQAHTTVP-GELQGYVGTQAYMA 499

Query: 220 --INTHLGKE-QSRRDDLEALGHMFMYFLRGSLPW 251
             + T    +   R  D+ ++G + +    G  PW
Sbjct: 500 PEVFTKTNSDGHGRLADIWSVGCVVVEMASGKRPW 604
>27546
          Length = 426

 Score = 36.6 bits (83), Expect = 0.019,   Method: Composition-based stats.
 Identities = 17/46 (36%), Positives = 29/46 (63%)
 Frame = -1

Query: 147 QLLSRMEYVHSKNLIYRDVKPENFLIGRQGNKKEHVIHIIDFGLAK 192
           Q+   ++Y+HS ++ +RD+K EN L+ ++ N K     I DFG A+
Sbjct: 156 QMAKALQYLHSHDIAHRDLKCENILLSKRLNVK-----IADFGFAR 34
>12786
          Length = 460

 Score = 36.2 bits (82), Expect = 0.030,   Method: Compositional matrix adjust.
 Identities = 28/94 (29%), Positives = 46/94 (48%), Gaps = 1/94 (1%)
 Frame = -3

Query: 147 QLLSRMEYVHSKNLIYRDVKPENFLIGRQGNKKEHVIHIIDFGLAKEYVDPETKKHIPYR 206
           ++L  ++ +H++ +I+ D+KP NF++   GN K     +IDFG+A      +T       
Sbjct: 386 EMLRAVKALHNEGVIHSDLKPANFML-VAGNLK-----LIDFGIANTLQQDKTSVL---- 237

Query: 207 EHKSLTGTARYMSINTHLGK-EQSRRDDLEALGH 239
              S  GT  YMS    +   + S  D +E  GH
Sbjct: 236 -KDSRVGTPSYMSPEAIMAACDDSADDSMEEDGH 138
>31489
          Length = 329

 Score = 35.8 bits (81), Expect = 0.037,   Method: Composition-based stats.
 Identities = 14/39 (35%), Positives = 25/39 (64%)
 Frame = +3

Query: 133 DRTFTLKTVLMIAIQLLSRMEYVHSKNLIYRDVKPENFL 171
           D+  T + +     Q+L  ++Y+HS N+++RD+KP N L
Sbjct: 147 DQPLTEEHIRYFLYQILRGLKYIHSANVVHRDLKPSNLL 263
>19761
          Length = 473

 Score = 35.8 bits (81), Expect = 0.041,   Method: Compositional matrix adjust.
 Identities = 24/105 (22%), Positives = 50/105 (47%), Gaps = 2/105 (1%)
 Frame = -3

Query: 139 KTVLMIAIQLLSRMEYVHSKN--LIYRDVKPENFLIGRQGNKKEHVIHIIDFGLAKEYVD 196
           + ++   +Q  S + Y+H+    +++RD+KP+N  +  +G+     + + D GLA++   
Sbjct: 423 RLIVCWLMQTASALNYMHTHTPVILHRDLKPQNIYVTEKGD-----VRLGDLGLARKLTG 259

Query: 197 PETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMF 241
           P            S  GT  Y+S      +  + + D+ +LG +F
Sbjct: 258 PADFA-------TSQVGTIMYLSPEILSQQPYNSKSDIWSLGCVF 145
>13066
          Length = 551

 Score = 35.4 bits (80), Expect = 0.049,   Method: Compositional matrix adjust.
 Identities = 20/73 (27%), Positives = 38/73 (52%)
 Frame = +3

Query: 147 QLLSRMEYVHSKNLIYRDVKPENFLIGRQGNKKEHVIHIIDFGLAKEYVDPETKKHIPYR 206
           Q+ + + Y+HS ++ +RD+K EN L+    N K     + DFG A   +    +K++   
Sbjct: 300 QMTTALNYLHSYDVAHRDLKCENILLSSHFNVK-----LADFGFACACITESGEKYMS-- 458

Query: 207 EHKSLTGTARYMS 219
             ++  G+A Y +
Sbjct: 459 --RTYCGSAAYAA 491
>11404
          Length = 563

 Score = 35.0 bits (79), Expect = 0.059,   Method: Compositional matrix adjust.
 Identities = 37/141 (26%), Positives = 66/141 (46%), Gaps = 12/141 (8%)
 Frame = +1

Query: 44  FRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPIKSRAP---QLHLEYRFYKQLGSAGEG 100
           + +   IG G+FG++    +   NE VAIK+  IK++ P   Q  +E +  + +      
Sbjct: 145 YEIDSLIGKGSFGQVVKAYDHTDNEQVAIKI--IKNKKPFLNQAQIEVKLLEMMNR--HD 312

Query: 101 LPQVYYFGPCGKYN------AMVLELLGPSLEDLFDLCD-RTFTLKTVLMIAIQLLSRME 153
               YY     ++        +V ELL  +L DL    + R  +L      A QL + + 
Sbjct: 313 TDNKYYIVRLKRHFMFRSHLCLVFELLSYNLYDLLRNTNFRGVSLNLTRKFAQQLCTALL 492

Query: 154 YVHS--KNLIYRDVKPENFLI 172
           ++ +   ++I+ D+KPEN L+
Sbjct: 493 FLATPEMSIIHCDLKPENILL 555
>14116
          Length = 1017

 Score = 33.1 bits (74), Expect = 0.25,   Method: Compositional matrix adjust.
 Identities = 20/70 (28%), Positives = 34/70 (48%), Gaps = 5/70 (7%)
 Frame = -1

Query: 137 TLKTVLMIAIQLLSRMEYVHSKNLIYRDVKPENFLIGRQGNKKEHVIHIIDFGLA----- 191
           T+K ++M  + +   M+Y+     ++RD+   N ++    + K     + DFGLA     
Sbjct: 327 TIKDLIMYGVDIARGMDYLAGLKFVHRDLAARNCMLDEDFHVK-----VADFGLARDIYE 163

Query: 192 KEYVDPETKK 201
           KEY   E KK
Sbjct: 162 KEYYSSENKK 133
>28157
          Length = 400

 Score = 32.7 bits (73), Expect = 0.29,   Method: Composition-based stats.
 Identities = 19/43 (44%), Positives = 26/43 (60%), Gaps = 3/43 (6%)
 Frame = +3

Query: 152 MEYVHS---KNLIYRDVKPENFLIGRQGNKKEHVIHIIDFGLA 191
           +EY+H    K LI+RD+KP N L+ + G K    + I DFG A
Sbjct: 255 VEYLHGMKPKALIHRDLKPPNLLLIQCGTK----LKICDFGTA 371
>17975
          Length = 449

 Score = 31.2 bits (69), Expect = 0.86,   Method: Composition-based stats.
 Identities = 13/45 (28%), Positives = 27/45 (60%)
 Frame = +3

Query: 147 QLLSRMEYVHSKNLIYRDVKPENFLIGRQGNKKEHVIHIIDFGLA 191
           Q++  + Y H  ++++RD+KPEN +      +K  ++ + DFG +
Sbjct: 291 QIVEAISYCHKLHVVHRDLKPENVVF----FEKPGLVKLTDFGFS 413
>05814
          Length = 1242

 Score = 30.0 bits (66), Expect = 1.9,   Method: Compositional matrix adjust.
 Identities = 15/28 (53%), Positives = 19/28 (67%)
 Frame = -2

Query: 159 NLIYRDVKPENFLIGRQGNKKEHVIHII 186
            LI R+V P+ FLI RQ N + HV HI+
Sbjct: 416 GLILREVFPQVFLIIRQLNHQWHVKHIL 333
>37602
          Length = 804

 Score = 30.0 bits (66), Expect = 2.3,   Method: Compositional matrix adjust.
 Identities = 14/58 (24%), Positives = 31/58 (53%)
 Frame = -1

Query: 122 GPSLEDLFDLCDRTFTLKTVLMIAIQLLSRMEYVHSKNLIYRDVKPENFLIGRQGNKK 179
           G S++D++ +     T   +  +  + L  + Y+H +  ++RD+K  N L+  +G+ K
Sbjct: 267 GGSMQDIYHVTG-PLTEPQIAFVCRETLKGLHYLHRRGKMHRDIKGANILLTEEGDVK 97
>32359
          Length = 928

 Score = 26.6 bits (57), Expect(2) = 3.6,   Method: Compositional matrix adjust.
 Identities = 32/132 (24%), Positives = 58/132 (43%), Gaps = 17/132 (12%)
 Frame = -1

Query: 47  GKKIGCGNFGELRLGKNLYTNEYVAIKL----EPIKSRAPQL----------HLEYRFYK 92
            K IG G+FG +   K + T+E VAIK     +  K+R  Q+           L++ FY 
Sbjct: 415 AKVIGNGSFGVVYQAKLVDTSELVAIKKVLQDKRFKNRELQIMRKLEHQNIVKLKFFFY- 239

Query: 93  QLGSAGEGLPQVYYFGPCGKYNAMVLELLGPSLEDL---FDLCDRTFTLKTVLMIAIQLL 149
              S+GE   +V+          +VLE +  ++  +   +    +T  +  + +   QL 
Sbjct: 238 ---SSGEKKDEVFL--------NLVLEYVPETVYRVARHYSKSKQTIPILYIKLYMYQLF 92

Query: 150 SRMEYVHSKNLI 161
             + Y+HS+  +
Sbjct: 91  RSLAYIHSQACV 56

 Score = 21.2 bits (43), Expect(2) = 3.6,   Method: Compositional matrix adjust.
 Identities = 6/11 (54%), Positives = 10/11 (90%)
 Frame = -3

Query: 162 YRDVKPENFLI 172
           +RD+KP+N L+
Sbjct: 56  HRDIKPQNLLL 24
>18731
          Length = 1299

 Score = 27.7 bits (60), Expect = 9.1,   Method: Compositional matrix adjust.
 Identities = 23/70 (32%), Positives = 36/70 (51%)
 Frame = -1

Query: 15   TKTMAQRNTHCSRPSGTSTSSGVLMVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKL 74
            T++ A+RNT  +  S  S  S   + G N +  K + C +FG LR   NL  +     +L
Sbjct: 1179 TQSRAKRNTTINISSXFSIHS-TFL*GXNPQKHKHLSCLSFGFLRFYPNLANSITQPTQL 1003

Query: 75   EPIKSRAPQL 84
            EP  ++ PQ+
Sbjct: 1002 EPTITQ-PQI 976
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|83921612|ref|NP_663342.3| thioredoxin domain
containing 5 [Mus musculus]
         (417 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

18455                                                                 139   2e-33
06936                                                                 101   7e-22
03582                                                                  84   1e-16
28335                                                                  69   4e-12
21509                                                                  48   7e-12
30644                                                                  51   1e-11
18943                                                                  59   4e-09
35861                                                                  57   1e-08
01000                                                                  53   2e-07
07257                                                                  49   5e-06
04510                                                                  49   5e-06
14392                                                                  49   5e-06
15159                                                                  46   3e-05
36159                                                                  46   4e-05
04779                                                                  37   0.013
>18455
          Length = 499

 Score =  139 bits (351), Expect = 2e-33,   Method: Compositional matrix adjust.
 Identities = 60/150 (40%), Positives = 91/150 (60%), Gaps = 2/150 (1%)
 Frame = +2

Query: 133 EAVKYQGPRDFETLENWMLQTLNXXXXXXXXXXXXXXXXXLKQ--GLYELSANNFELHVS 190
           E+V+++G RD   + +++ Q LN                       + +L+ + F  HVS
Sbjct: 8   ESVRFKGTRDLPAITDFINQELNTPAVEDLSDQQLKDESQNPNVGKVVDLTEDTFAKHVS 187

Query: 191 QGNHFIKFFAPWCGHCKALAPTWEQLALGLEHSETVKIGKVDCTQHYAVCSEHQVRGYPT 250
            GNHF+KFFAPWC HC+ LAP WE+LA  L    +  I K+DCTQ+ ++C + +V+GYPT
Sbjct: 188 SGNHFVKFFAPWCSHCQRLAPIWEELAKALIKEPSATISKIDCTQYRSICQDFEVKGYPT 367

Query: 251 LLWFRDGKKVDQYKGKRDLESLRDYVQSQL 280
           LLW  DGKK+++Y G RD+ +L+ YV+  +
Sbjct: 368 LLWIEDGKKIEKYAGARDMVTLKTYVEKMI 457

 Score =  118 bits (295), Expect = 6e-27,   Method: Compositional matrix adjust.
 Identities = 56/148 (37%), Positives = 89/148 (60%)
 Frame = +2

Query: 262 QYKGKRDLESLRDYVQSQLQGSEAAPETVEPSEAPVMAAEPTGDKGTVLALTEKSFEDTI 321
           ++KG RDL ++ D++  +L      P   + S+  +       + G V+ LTE +F   +
Sbjct: 17  RFKGTRDLPAITDFINQELN----TPAVEDLSDQQLKDESQNPNVGKVVDLTEDTFAKHV 184

Query: 322 AQGITFVKFYAPWCGHCKNLAPTWEELSKKEFPGLSDVTIAEVDCTAERNVCSKYSVRGY 381
           + G  FVKF+APWC HC+ LAP WEEL+K      S  TI+++DCT  R++C  + V+GY
Sbjct: 185 SSGNHFVKFFAPWCSHCQRLAPIWEELAKALIKEPS-ATISKIDCTQYRSICQDFEVKGY 361

Query: 382 PTLLLFRGGEKVGEHNGGRDLDSLHSFV 409
           PTLL    G+K+ ++ G RD+ +L ++V
Sbjct: 362 PTLLWIEDGKKIEKYAGARDMVTLKTYV 445

 Score = 91.7 bits (226), Expect = 5e-19,   Method: Compositional matrix adjust.
 Identities = 42/109 (38%), Positives = 62/109 (56%), Gaps = 2/109 (1%)
 Frame = +2

Query: 44  QDPHAKHL--YTADMFTHGIQSAAHFVMFFAPWCGHCQRLQPTWNDLGDKYNSMEDAKVY 101
           Q+P+   +   T D F   + S  HFV FFAPWC HCQRL P W +L      +++    
Sbjct: 125 QNPNVGKVVDLTEDTFAKHVSSGNHFVKFFAPWCSHCQRLAPIWEELAKAL--IKEPSAT 298

Query: 102 VAKVDCTADSDVCSAQGVRGYPTLKFFKPGQEAVKYQGPRDFETLENWM 150
           ++K+DCT    +C    V+GYPTL + + G++  KY G RD  TL+ ++
Sbjct: 299 ISKIDCTQYRSICQDFEVKGYPTLLWIEDGKKIEKYAGARDMVTLKTYV 445
>06936
          Length = 2198

 Score =  101 bits (251), Expect = 7e-22,   Method: Compositional matrix adjust.
 Identities = 48/106 (45%), Positives = 67/106 (63%), Gaps = 1/106 (0%)
 Frame = +3

Query: 309 VLALTEKSFEDTIAQ-GITFVKFYAPWCGHCKNLAPTWEELSKKEFPGLSDVTIAEVDCT 367
           VL L +  F+ TI +  +  V+F+APWCGHCK LAP +E  +         V +A+VDCT
Sbjct: 150 VLDLKKSDFQSTIEKHSLMLVEFFAPWCGHCKKLAPQYELAATALLKNDPPVPLAKVDCT 329

Query: 368 AERNVCSKYSVRGYPTLLLFRGGEKVGEHNGGRDLDSLHSFVLRQA 413
            E +VCSKY V GYPTL +FRGGE   +++G RD D +  ++ + A
Sbjct: 330 EETDVCSKYGVSGYPTLKVFRGGEVNKDYDGPRDKDGIVKYMAKMA 467

 Score = 87.0 bits (214), Expect = 1e-17,   Method: Compositional matrix adjust.
 Identities = 41/86 (47%), Positives = 54/86 (62%)
 Frame = +3

Query: 67  FVMFFAPWCGHCQRLQPTWNDLGDKYNSMEDAKVYVAKVDCTADSDVCSAQGVRGYPTLK 126
            V FFAPWCGHC++L P + +L        D  V +AKVDCT ++DVCS  GV GYPTLK
Sbjct: 207 LVEFFAPWCGHCKKLAPQY-ELAATALLKNDPPVPLAKVDCTEETDVCSKYGVSGYPTLK 383

Query: 127 FFKPGQEAVKYQGPRDFETLENWMLQ 152
            F+ G+    Y GPRD + +  +M +
Sbjct: 384 VFRGGEVNKDYDGPRDKDGIVKYMAK 461

 Score = 84.7 bits (208), Expect = 6e-17,   Method: Compositional matrix adjust.
 Identities = 44/120 (36%), Positives = 68/120 (56%), Gaps = 2/120 (1%)
 Frame = +3

Query: 177 LYELSANNFELHVSQGN-HFIKFFAPWCGHCKALAPTWEQLALGL-EHSETVKIGKVDCT 234
           + +L  ++F+  + + +   ++FFAPWCGHCK LAP +E  A  L ++   V + KVDCT
Sbjct: 150 VLDLKKSDFQSTIEKHSLMLVEFFAPWCGHCKKLAPQYELAATALLKNDPPVPLAKVDCT 329

Query: 235 QHYAVCSEHQVRGYPTLLWFRDGKKVDQYKGKRDLESLRDYVQSQLQGSEAAPETVEPSE 294
           +   VCS++ V GYPTL  FR G+    Y G RD + +  Y+      +    ++VE  E
Sbjct: 330 EETDVCSKYGVSGYPTLKVFRGGEVNKDYDGPRDKDGIVKYMAKMAGPTSKELKSVEEYE 509

 Score = 80.9 bits (198), Expect = 9e-16,   Method: Compositional matrix adjust.
 Identities = 47/153 (30%), Positives = 80/153 (52%), Gaps = 4/153 (2%)
 Frame = +3

Query: 269  LESLRDYVQSQLQGSEAAPETVEPSEAPVMAAEPTGDKGTVLALTEKSFEDTI--AQGIT 326
            +++   +V+  L G   A    EP         P   +  V     ++FE+ +   +   
Sbjct: 1095 MDTFEQFVRDMLDGKLEAYMKSEPV--------PDNSENAVKVAVGRNFEELVNDPEKDV 1250

Query: 327  FVKFYAPWCGHCKNLAPTWEELSKKEFPGLSDVTIAEVDCTAERNVCSKYSVRGYPTLLL 386
             ++FYAPWCGHCK LAP ++EL++K      ++ IA++D TA  +V   Y VRG+PTL  
Sbjct: 1251 LIEFYAPWCGHCKTLAPKYDELAEK-LKNEPEIVIAKMDATA-NDVPPPYDVRGFPTLYF 1424

Query: 387  FRGGEKVG--EHNGGRDLDSLHSFVLRQAKDEL 417
               G K    ++ GGR+++    ++ ++A +EL
Sbjct: 1425 APKGSKSSPKKYEGGREVNDFVKYLAKEATNEL 1523

 Score = 70.9 bits (172), Expect = 9e-13,   Method: Compositional matrix adjust.
 Identities = 40/107 (37%), Positives = 63/107 (58%), Gaps = 8/107 (7%)
 Frame = +3

Query: 184  NFELHVS--QGNHFIKFFAPWCGHCKALAPTWEQLALGLEHSETVKIGKVDCTQHYAVCS 241
            NFE  V+  + +  I+F+APWCGHCK LAP +++LA  L++   + I K+D T +  V  
Sbjct: 1212 NFEELVNDPEKDVLIEFYAPWCGHCKTLAPKYDELAEKLKNEPEIVIAKMDATAN-DVPP 1388

Query: 242  EHQVRGYPTLLWFRDGKKVD--QYKGKRDLESLRDYV----QSQLQG 282
             + VRG+PTL +   G K    +Y+G R++     Y+     ++LQG
Sbjct: 1389 PYDVRGFPTLYFAPKGSKSSPKKYEGGREVNDFVKYLAKEATNELQG 1529

 Score = 63.5 bits (153), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 31/88 (35%), Positives = 53/88 (60%), Gaps = 2/88 (2%)
 Frame = +3

Query: 67   FVMFFAPWCGHCQRLQPTWNDLGDKYNSMEDAKVYVAKVDCTADSDVCSAQGVRGYPTLK 126
             + F+APWCGHC+ L P +++L +K  +  + ++ +AK+D TA+ DV     VRG+PTL 
Sbjct: 1251 LIEFYAPWCGHCKTLAPKYDELAEKLKN--EPEIVIAKMDATAN-DVPPPYDVRGFPTLY 1421

Query: 127  FFKPGQEAV--KYQGPRDFETLENWMLQ 152
            F   G ++   KY+G R+      ++ +
Sbjct: 1422 FAPKGSKSSPKKYEGGREVNDFVKYLAK 1505
>03582
          Length = 1967

 Score = 84.0 bits (206), Expect = 1e-16,   Method: Compositional matrix adjust.
 Identities = 56/148 (37%), Positives = 84/148 (56%), Gaps = 6/148 (4%)
 Frame = +3

Query: 268  DLESLRDYVQSQLQGSEAAPETVEPSEAPVMAAE-PTG-DKGTVLALTEKSFEDTI---A 322
            D E+++ +VQ  L G            A +M+ + P+  D   V  L  K+F++      
Sbjct: 1029 DTETIKKFVQDFLDGK---------LNAHLMSEDVPSDWDAKPVKVLVGKNFKEVALDKT 1181

Query: 323  QGITFVKFYAPWCGHCKNLAPTWEELSKKEFPGLSDVTIAEVDCTAERNVCSKYSVRGYP 382
            +G+ FV+FYAPWCGHCK LAP W+EL+ K F   +DV IA++D TA  N   +  V+ +P
Sbjct: 1182 KGV-FVEFYAPWCGHCKQLAPIWDELADK-FTDKADVVIAKMDSTA--NEIEEVKVQSFP 1349

Query: 383  TLLLF-RGGEKVGEHNGGRDLDSLHSFV 409
            TL  F +  ++V ++NG R LD+   FV
Sbjct: 1350 TLKYFPKDSDEVIDYNGERTLDAFVKFV 1433

 Score = 75.9 bits (185), Expect = 3e-14,   Method: Compositional matrix adjust.
 Identities = 38/93 (40%), Positives = 57/93 (61%), Gaps = 1/93 (1%)
 Frame = +3

Query: 195  FIKFFAPWCGHCKALAPTWEQLALGLEHSETVKIGKVDCTQHYAVCSEHQVRGYPTLLWF 254
            F++F+APWCGHCK LAP W++LA        V I K+D T +     E +V+ +PTL +F
Sbjct: 1191 FVEFYAPWCGHCKQLAPIWDELADKFTDKADVVIAKMDSTANE--IEEVKVQSFPTLKYF 1364

Query: 255  -RDGKKVDQYKGKRDLESLRDYVQSQLQGSEAA 286
             +D  +V  Y G+R L++   +V+S   G+E A
Sbjct: 1365 PKDSDEVIDYNGERTLDAFVKFVES--GGTEGA 1457

 Score = 73.2 bits (178), Expect = 2e-13,   Method: Compositional matrix adjust.
 Identities = 45/114 (39%), Positives = 63/114 (55%), Gaps = 1/114 (0%)
 Frame = +2

Query: 295 APVMAAEPTGDKGTVLALTEKSFEDTIAQG-ITFVKFYAPWCGHCKNLAPTWEELSKKEF 353
           A V A +   D+G V  LT K+F+  + +     V+FYAPWCGHCK LAP + + ++   
Sbjct: 80  ALVFADDVKQDEG-VYVLTTKNFDSFVKENEFVLVEFYAPWCGHCKALAPEYAKAAQTLK 256

Query: 354 PGLSDVTIAEVDCTAERNVCSKYSVRGYPTLLLFRGGEKVGEHNGGRDLDSLHS 407
              SDV +A+VD T E ++     VRGYPT L F   EK+     G  L +L +
Sbjct: 257 DENSDVKLAKVDATIETSLGENMGVRGYPT-LKFSVMEKILNIPAGAKLQTLSA 415

 Score = 72.8 bits (177), Expect = 2e-13,   Method: Compositional matrix adjust.
 Identities = 34/85 (40%), Positives = 50/85 (58%), Gaps = 1/85 (1%)
 Frame = +3

Query: 67   FVMFFAPWCGHCQRLQPTWNDLGDKYNSMEDAKVYVAKVDCTADSDVCSAQGVRGYPTLK 126
            FV F+APWCGHC++L P W++L DK+    D  V +AK+D TA+        V+ +PTLK
Sbjct: 1191 FVEFYAPWCGHCKQLAPIWDELADKFTDKAD--VVIAKMDSTANE--IEEVKVQSFPTLK 1358

Query: 127  FF-KPGQEAVKYQGPRDFETLENWM 150
            +F K   E + Y G R  +    ++
Sbjct: 1359 YFPKDSDEVIDYNGERTLDAFVKFV 1433

 Score = 69.7 bits (169), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 34/79 (43%), Positives = 49/79 (62%), Gaps = 2/79 (2%)
 Frame = +2

Query: 175 QGLYELSANNFELHVSQGNH-FIKFFAPWCGHCKALAPTWEQLALGL-EHSETVKIGKVD 232
           +G+Y L+  NF+  V +     ++F+APWCGHCKALAP + + A  L + +  VK+ KVD
Sbjct: 113 EGVYVLTTKNFDSFVKENEFVLVEFYAPWCGHCKALAPEYAKAAQTLKDENSDVKLAKVD 292

Query: 233 CTQHYAVCSEHQVRGYPTL 251
            T   ++     VRGYPTL
Sbjct: 293 ATIETSLGENMGVRGYPTL 349

 Score = 62.0 bits (149), Expect = 4e-10,   Method: Compositional matrix adjust.
 Identities = 33/86 (38%), Positives = 47/86 (54%)
 Frame = +2

Query: 42  VEQDPHAKHLYTADMFTHGIQSAAHFVMFFAPWCGHCQRLQPTWNDLGDKYNSMEDAKVY 101
           V+QD     L T +  +   ++    V F+APWCGHC+ L P +          E++ V 
Sbjct: 101 VKQDEGVYVLTTKNFDSFVKENEFVLVEFYAPWCGHCKALAPEYAKAAQTLKD-ENSDVK 277

Query: 102 VAKVDCTADSDVCSAQGVRGYPTLKF 127
           +AKVD T ++ +    GVRGYPTLKF
Sbjct: 278 LAKVDATIETSLGENMGVRGYPTLKF 355
>28335
          Length = 601

 Score = 68.6 bits (166), Expect = 4e-12,   Method: Compositional matrix adjust.
 Identities = 37/122 (30%), Positives = 67/122 (54%), Gaps = 6/122 (4%)
 Frame = -2

Query: 302 PTGDKGTVLALTEKSFEDTI--AQGITFVKFYAPWCGHCKNLAPTWEELSK--KEFPGLS 357
           P  ++G V     ++F+  +   +    ++FYAPWCGHC+ L P + EL+   K+ P   
Sbjct: 567 PQNEEGPVKTAVGRTFDKIVNNPKKDVLIEFYAPWCGHCQQLEPKYNELATLLKDEP--- 397

Query: 358 DVTIAEVDCTAERNVCSKYSVRGYPTLLLF--RGGEKVGEHNGGRDLDSLHSFVLRQAKD 415
           D+  A++D TA  +  + Y V+G+P +     R  E   ++ G R++D++  ++ R+A  
Sbjct: 396 DIVXAKIDATA-NDTPTPYEVKGFPAIYFSPKRFKEFPKKYEGDREVDAMLKYIAREATS 220

Query: 416 EL 417
           EL
Sbjct: 219 EL 214

 Score = 58.9 bits (141), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 31/107 (28%), Positives = 60/107 (56%), Gaps = 8/107 (7%)
 Frame = -2

Query: 195 FIKFFAPWCGHCKALAPTWEQLALGLEHSETVKIGKVDCTQHYAVCSEHQVRGYPTLLW- 253
            I+F+APWCGHC+ L P + +LA  L+    +   K+D T +    + ++V+G+P + + 
Sbjct: 486 LIEFYAPWCGHCQQLEPKYNELATLLKDEPDIVXAKIDATAN-DTPTPYEVKGFPAIYFS 310

Query: 254 ---FRDGKKVDQYKGKRDLESLRDYV----QSQLQGSEAAPETVEPS 293
              F++  K  +Y+G R+++++  Y+     S+L+G +      EP 
Sbjct: 309 PKRFKEFPK--KYEGDREVDAMLKYIAREATSELRGYDRQGRKREPK 175

 Score = 58.2 bits (139), Expect = 6e-09,   Method: Compositional matrix adjust.
 Identities = 29/87 (33%), Positives = 50/87 (57%), Gaps = 3/87 (3%)
 Frame = -2

Query: 67  FVMFFAPWCGHCQRLQPTWNDLGDKYNSMEDAKVYVAKVDCTADSDVCSAQGVRGYPTLK 126
            + F+APWCGHCQ+L+P +N+L        D  +  AK+D TA+ D  +   V+G+P + 
Sbjct: 486 LIEFYAPWCGHCQQLEPKYNELATLLKDEPD--IVXAKIDATAN-DTPTPYEVKGFPAI- 319

Query: 127 FFKP---GQEAVKYQGPRDFETLENWM 150
           +F P    +   KY+G R+ + +  ++
Sbjct: 318 YFSPKRFKEFPKKYEGDREVDAMLKYI 238
>21509
          Length = 754

 Score = 44.3 bits (103), Expect(2) = 7e-12,   Method: Compositional matrix adjust.
 Identities = 19/35 (54%), Positives = 23/35 (65%), Gaps = 1/35 (2%)
 Frame = -1

Query: 312 LTEKSFEDTIAQGI-TFVKFYAPWCGHCKNLAPTW 345
           LT+ +FE  IA    T V FYAPWCGHCK + P +
Sbjct: 346 LTDATFESFIAANRRTLVMFYAPWCGHCKKMKPAY 242

 Score = 43.5 bits (101), Expect(2) = 7e-12,   Method: Compositional matrix adjust.
 Identities = 28/106 (26%), Positives = 49/106 (46%), Gaps = 3/106 (2%)
 Frame = -3

Query: 180 LSANNFELHVSQGNHFIKFFAPWCGHCKALAPTWEQLALGLEHSETVKIGKV---DCTQH 236
           L+ + F+  VS  +  +  F P   H   +      +  G  H    K+G V   D T  
Sbjct: 713 LTKDTFDTFVSTHSSVLVMFTP---HGADIVKNEASVWRGCCHHSRAKLGAVAAVDATLD 543

Query: 237 YAVCSEHQVRGYPTLLWFRDGKKVDQYKGKRDLESLRDYVQSQLQG 282
             + +++ V+GYPTL +F+DGK   +Y G R  ++   +++    G
Sbjct: 542 PELGNKYDVKGYPTLKYFKDGKLAFEYSGGRSSDAFVSFMKKAGAG 405

 Score = 45.4 bits (106), Expect(3) = 2e-11,   Method: Compositional matrix adjust.
 Identities = 21/49 (42%), Positives = 31/49 (63%)
 Frame = -3

Query: 102 VAKVDCTADSDVCSAQGVRGYPTLKFFKPGQEAVKYQGPRDFETLENWM 150
           VA VD T D ++ +   V+GYPTLK+FK G+ A +Y G R  +   ++M
Sbjct: 569 VAAVDATLDPELGNKYDVKGYPTLKYFKDGKLAFEYSGGRSSDAFVSFM 423

 Score = 35.0 bits (79), Expect(3) = 2e-11,   Method: Compositional matrix adjust.
 Identities = 14/40 (35%), Positives = 21/40 (52%), Gaps = 1/40 (2%)
 Frame = -1

Query: 179 ELSANNFELHVSQGNH-FIKFFAPWCGHCKALAPTWEQLA 217
            L+   FE  ++      + F+APWCGHCK + P +   A
Sbjct: 349 HLTDATFESFIAANRRTLVMFYAPWCGHCKKMKPAYMAAA 230

 Score = 25.4 bits (54), Expect(3) = 2e-11,   Method: Compositional matrix adjust.
 Identities = 9/23 (39%), Positives = 14/23 (60%)
 Frame = -2

Query: 58  THGIQSAAHFVMFFAPWCGHCQR 80
            H +  + H    +APWCGHC++
Sbjct: 684 VHTLVCSCHV---YAPWCGHCKK 625

 Score = 48.1 bits (113), Expect = 6e-06,   Method: Compositional matrix adjust.
 Identities = 32/105 (30%), Positives = 51/105 (48%), Gaps = 1/105 (0%)
 Frame = -3

Query: 306 KGTVLALTEKSFEDTIAQGITFVKFYAPWCGH-CKNLAPTWEELSKKEFPGLSDVTIAEV 364
           KG    LT+ +F+  ++   + +  + P      KN A  W          L    +A V
Sbjct: 731 KGFHWFLTKDTFDTFVSTHSSVLVMFTPHGADIVKNEASVWRGCCHHSRAKLG--AVAAV 558

Query: 365 DCTAERNVCSKYSVRGYPTLLLFRGGEKVGEHNGGRDLDSLHSFV 409
           D T +  + +KY V+GYPTL  F+ G+   E++GGR  D+  SF+
Sbjct: 557 DATLDPELGNKYDVKGYPTLKYFKDGKLAFEYSGGRSSDAFVSFM 423

 Score = 38.5 bits (88), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 11/19 (57%), Positives = 17/19 (89%)
 Frame = -1

Query: 67  FVMFFAPWCGHCQRLQPTW 85
            VMF+APWCGHC++++P +
Sbjct: 298 LVMFYAPWCGHCKKMKPAY 242
>30644
          Length = 845

 Score = 51.2 bits (121), Expect(2) = 1e-11,   Method: Compositional matrix adjust.
 Identities = 34/110 (30%), Positives = 54/110 (49%), Gaps = 1/110 (0%)
 Frame = -1

Query: 231 VDCTQHYAVCSEHQVRGYPTLLWFRDGKKVDQYKGKRDLESLRDYVQSQLQGSEAAPETV 290
           VD      V +++ + G+PTL +F  GK   +Y G+ + + +  ++ S  +  E   +  
Sbjct: 305 VDKPHMKGVQAQYNITGFPTLYYFEKGKLKYRYGGENNKDGIISWL-SNPKPPEEPKKEA 129

Query: 291 EPSEAPVMAAEPTGDKGTVLALTEKSFEDTIAQGIT-FVKFYAPWCGHCK 339
           E SE P   A           L + +F+D + Q  +  V FYAPWCGHCK
Sbjct: 128 EWSEEPSEVAH----------LEDSNFDDFLKQHPSVLVMFYAPWCGHCK 9

 Score = 36.2 bits (82), Expect(2) = 1e-11,   Method: Compositional matrix adjust.
 Identities = 28/120 (23%), Positives = 44/120 (36%), Gaps = 1/120 (0%)
 Frame = -3

Query: 99  KVYVAKVDCTADSDVCSAQGVRGYP-TLKFFKPGQEAVKYQGPRDFETLENWMLQTLNXX 157
           K  +A V+C  D   C    V      LK +K G+    Y      +++ N++L      
Sbjct: 687 KSTMAYVNCGEDKKFCKKLKVSPSSFELKHYKDGEFNKDYDRKLALKSMVNFLLXPTGDI 508

Query: 158 XXXXXXXXXXXXXXXLKQGLYELSANNFELHVSQGNHFIKFFAPWCGHCKALAPTWEQLA 217
                             GL +L      L   +    + F+APWCG+CK + P +   A
Sbjct: 507 PWDEDPTATDVVHIDTDDGLTKL------LKKDKSAALVMFYAPWCGYCKRMKPDFAAAA 346

 Score = 44.3 bits (103), Expect(2) = 2e-10,   Method: Compositional matrix adjust.
 Identities = 19/48 (39%), Positives = 31/48 (64%), Gaps = 5/48 (10%)
 Frame = -3

Query: 43  EQDPHAK---HLYTADMFTHGIQS--AAHFVMFFAPWCGHCQRLQPTW 85
           ++DP A    H+ T D  T  ++   +A  VMF+APWCG+C+R++P +
Sbjct: 501 DEDPTATDVVHIDTDDGLTKLLKKDKSAALVMFYAPWCGYCKRMKPDF 358

 Score = 38.9 bits (89), Expect(2) = 2e-10,   Method: Compositional matrix adjust.
 Identities = 25/104 (24%), Positives = 44/104 (42%), Gaps = 1/104 (0%)
 Frame = -1

Query: 105 VDCTADSDVCSAQGVRGYPTLKFFKPGQEAVKYQGPRDFETLENWMLQTLNXXXXXXXXX 164
           VD      V +   + G+PTL +F+ G+   +Y G  + + + +W+              
Sbjct: 305 VDKPHMKGVQAQYNITGFPTLYYFEKGKLKYRYGGENNKDGIISWLSNPKPPEEPKKEAE 126

Query: 165 XXXXXXXXLKQGLYELSANNFELHVSQG-NHFIKFFAPWCGHCK 207
                       +  L  +NF+  + Q  +  + F+APWCGHCK
Sbjct: 125 WSEEPSE-----VAHLEDSNFDDFLKQHPSVLVMFYAPWCGHCK 9

 Score = 39.3 bits (90), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 32/116 (27%), Positives = 53/116 (45%), Gaps = 1/116 (0%)
 Frame = -3

Query: 231 VDCTQHYAVCSEHQVRGYP-TLLWFRDGKKVDQYKGKRDLESLRDYVQSQLQGSEAAPET 289
           V+C +    C + +V      L  ++DG+    Y  K  L+S+ +++   L  +   P  
Sbjct: 669 VNCGEDKKFCKKLKVSPSSFELKHYKDGEFNKDYDRKLALKSMVNFL---LXPTGDIPWD 499

Query: 290 VEPSEAPVMAAEPTGDKGTVLALTEKSFEDTIAQGITFVKFYAPWCGHCKNLAPTW 345
            +P+   V+  + T D  T L   +KS           V FYAPWCG+CK + P +
Sbjct: 498 EDPTATDVVHID-TDDGLTKLLKKDKS--------AALVMFYAPWCGYCKRMKPDF 358

 Score = 34.7 bits (78), Expect = 0.075,   Method: Compositional matrix adjust.
 Identities = 14/38 (36%), Positives = 21/38 (55%)
 Frame = -1

Query: 43  EQDPHAKHLYTADMFTHGIQSAAHFVMFFAPWCGHCQR 80
           E+     HL  ++      Q  +  VMF+APWCGHC++
Sbjct: 119 EEPSEVAHLEDSNFDDFLKQHPSVLVMFYAPWCGHCKK 6
>18943
          Length = 1035

 Score = 58.9 bits (141), Expect = 4e-09,   Method: Compositional matrix adjust.
 Identities = 36/97 (37%), Positives = 50/97 (51%), Gaps = 14/97 (14%)
 Frame = +2

Query: 335 CGHCKNL----------APTWEELSKK---EFPGLSDVTIAEVDCTAERNVCSKYSVRGY 381
           CG C+ L           PT++E S+K   EF     V  A+VDC  E  + S+Y +  Y
Sbjct: 170 CGVCQLLCRLVSLQSDSGPTFDEASRKISEEFTQPGKVLFAKVDCDKEVTIASQYRISKY 349

Query: 382 PTLLLFRGGEKV-GEHNGGRDLDSLHSFVLRQAKDEL 417
           PTL LFR G+ V  E  G R  D+L +F+  + KD +
Sbjct: 350 PTLKLFRNGQMVKKEFRGQRSADALAAFIREELKDSV 460

 Score = 49.3 bits (116), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 28/107 (26%), Positives = 55/107 (51%), Gaps = 15/107 (14%)
 Frame = +2

Query: 203 CGHCKAL----------APTWEQLALGLEHSET----VKIGKVDCTQHYAVCSEHQVRGY 248
           CG C+ L           PT+++ +  +    T    V   KVDC +   + S++++  Y
Sbjct: 170 CGVCQLLCRLVSLQSDSGPTFDEASRKISEEFTQPGKVLFAKVDCDKEVTIASQYRISKY 349

Query: 249 PTLLWFRDGKKV-DQYKGKRDLESLRDYVQSQLQGSEAAPETVEPSE 294
           PTL  FR+G+ V  +++G+R  ++L  +++ +L+ S     T++  E
Sbjct: 350 PTLKLFRNGQMVKKEFRGQRSADALAAFIREELKDSVVDHNTLDKLE 490

 Score = 43.9 bits (102), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 29/93 (31%), Positives = 44/93 (47%), Gaps = 13/93 (13%)
 Frame = +2

Query: 75  CGHCQRL----------QPTWNDLGDKYNS--MEDAKVYVAKVDCTADSDVCSAQGVRGY 122
           CG CQ L           PT+++   K +    +  KV  AKVDC  +  + S   +  Y
Sbjct: 170 CGVCQLLCRLVSLQSDSGPTFDEASRKISEEFTQPGKVLFAKVDCDKEVTIASQYRISKY 349

Query: 123 PTLKFFKPGQEAVK-YQGPRDFETLENWMLQTL 154
           PTLK F+ GQ   K ++G R  + L  ++ + L
Sbjct: 350 PTLKLFRNGQMVKKEFRGQRSADALAAFIREEL 448

 Score = 32.0 bits (71), Expect = 0.45,   Method: Compositional matrix adjust.
 Identities = 15/41 (36%), Positives = 21/41 (51%), Gaps = 1/41 (2%)
 Frame = +3

Query: 304 GDKGTVLALTEKSFEDTIAQG-ITFVKFYAPWCGHCKNLAP 343
           G  G  +AL   +    I++  + FV FYA WC   + LAP
Sbjct: 105 GHAGDAVALNNDNINTIISRNDVVFVNFYADWCRFSQILAP 227
>35861
          Length = 850

 Score = 57.0 bits (136), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 43/135 (31%), Positives = 63/135 (46%), Gaps = 12/135 (8%)
 Frame = +3

Query: 249 PTLLWFRDGKKVDQYK---GKRDLESLRDYVQSQLQG-------SEAAPETVEPSEAPVM 298
           P +   + G ++ +YK   G  D  ++  +VQ  + G       SE  PE  +       
Sbjct: 408 PAVRLIKLGDEMTKYKPESGDLDTATISKFVQDFMDGKLKPHLKSEEVPEDWD------- 566

Query: 299 AAEPTGDKGTVLALTEKSFEDTIAQGI--TFVKFYAPWCGHCKNLAPTWEELSKKEFPGL 356
            A+P      V  L  K+F++         FV+FYAPWCGHCK L P W+EL +K F   
Sbjct: 567 -AKP------VKVLVSKNFKEVALDKSKDVFVEFYAPWCGHCKQLVPIWDELGEK-FQDS 722

Query: 357 SDVTIAEVDCTAERN 371
            DV IA+     +R+
Sbjct: 723 DDVVIAKNGLHGQRS 767

 Score = 51.6 bits (122), Expect = 6e-07,   Method: Compositional matrix adjust.
 Identities = 21/43 (48%), Positives = 31/43 (72%)
 Frame = +3

Query: 62  QSAAHFVMFFAPWCGHCQRLQPTWNDLGDKYNSMEDAKVYVAK 104
           +S   FV F+APWCGHC++L P W++LG+K+   +D  V +AK
Sbjct: 621 KSKDVFVEFYAPWCGHCKQLVPIWDELGEKFQDSDD--VVIAK 743

 Score = 51.2 bits (121), Expect = 7e-07,   Method: Compositional matrix adjust.
 Identities = 31/112 (27%), Positives = 50/112 (44%), Gaps = 4/112 (3%)
 Frame = +3

Query: 123 PTLKFFKPGQEAVKYQ---GPRDFETLENWMLQTLNXXXXXXXXXXXXXXXXXLKQGLYE 179
           P ++  K G E  KY+   G  D  T+  ++   ++                  K     
Sbjct: 408 PAVRLIKLGDEMTKYKPESGDLDTATISKFVQDFMDGKLKPHLKSEEVPEDWDAKPVKVL 587

Query: 180 LSANNFELHVSQGNH-FIKFFAPWCGHCKALAPTWEQLALGLEHSETVKIGK 230
           +S N  E+ + +    F++F+APWCGHCK L P W++L    + S+ V I K
Sbjct: 588 VSKNFKEVALDKSKDVFVEFYAPWCGHCKQLVPIWDELGEKFQDSDDVVIAK 743
>01000
          Length = 1541

 Score = 53.1 bits (126), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 22/54 (40%), Positives = 35/54 (64%)
 Frame = -1

Query: 231  VDCTQHYAVCSEHQVRGYPTLLWFRDGKKVDQYKGKRDLESLRDYVQSQLQGSE 284
            VDCT+    C+   +RGYPTL  F++GK+ + +KG R L+ L+++V   L  +E
Sbjct: 1541 VDCTKQSETCNAQSIRGYPTLAVFQNGKRQEDFKGTRSLDDLQEFVDGFLTHTE 1380

 Score = 50.8 bits (120), Expect = 9e-07,   Method: Compositional matrix adjust.
 Identities = 21/46 (45%), Positives = 29/46 (63%)
 Frame = -1

Query: 364  VDCTAERNVCSKYSVRGYPTLLLFRGGEKVGEHNGGRDLDSLHSFV 409
            VDCT +   C+  S+RGYPTL +F+ G++  +  G R LD L  FV
Sbjct: 1541 VDCTKQSETCNAQSIRGYPTLAVFQNGKRQEDFKGTRSLDDLQEFV 1404

 Score = 49.3 bits (116), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 19/46 (41%), Positives = 30/46 (65%)
 Frame = -1

Query: 105  VDCTADSDVCSAQGVRGYPTLKFFKPGQEAVKYQGPRDFETLENWM 150
            VDCT  S+ C+AQ +RGYPTL  F+ G+    ++G R  + L+ ++
Sbjct: 1541 VDCTKQSETCNAQSIRGYPTLAVFQNGKRQEDFKGTRSLDDLQEFV 1404
>07257
          Length = 1477

 Score = 48.5 bits (114), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 26/87 (29%), Positives = 39/87 (44%), Gaps = 1/87 (1%)
 Frame = -3

Query: 68   VMFFAPWCGHCQRLQPTWNDLGDKYNSMEDAKVYVAKVDCTADSDVCSAQGVRGYPTLKF 127
            VMF+APWC  C    P +N L   +  +E     V  VD    S++ +  G    P +  
Sbjct: 1283 VMFYAPWCHFCANTAPHYNALARAFPQLE-----VLAVDTVHFSNLNARFGTVAVPNIML 1119

Query: 128  FKPGQEAVKY-QGPRDFETLENWMLQT 153
            F   + AV++    RDF T   ++  T
Sbjct: 1118 FHQSRSAVRFNHTERDFHTFLQFIANT 1038

 Score = 46.6 bits (109), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 25/83 (30%), Positives = 37/83 (44%), Gaps = 1/83 (1%)
 Frame = -3

Query: 328  VKFYAPWCGHCKNLAPTWEELSKKEFPGLSDVTIAEVDCTAERNVCSKYSVRGYPTLLLF 387
            V FYAPWC  C N AP +  L++  FP L    +  VD     N+ +++     P ++LF
Sbjct: 1283 VMFYAPWCHFCANTAPHYNALARA-FPQLE---VLAVDTVHFSNLNARFGTVAVPNIMLF 1116

Query: 388  RGGEKVGEHNGG-RDLDSLHSFV 409
                     N   RD  +   F+
Sbjct: 1115 HQSRSAVRFNHTERDFHTFLQFI 1047

 Score = 38.1 bits (87), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 23/118 (19%), Positives = 50/118 (42%), Gaps = 3/118 (2%)
 Frame = -3

Query: 196  IKFFAPWCGHCKALAPTWEQLALGLEHSETVKIGKVDCTQHYAVCSEHQVRGYPTLLWFR 255
            + F+APWC  C   AP +  LA      E + +  V  +    + +       P ++ F 
Sbjct: 1283 VMFYAPWCHFCANTAPHYNALARAFPQLEVLAVDTVHFSN---LNARFGTVAVPNIMLFH 1113

Query: 256  DGKKVDQYK-GKRDLESLRDYVQSQ--LQGSEAAPETVEPSEAPVMAAEPTGDKGTVL 310
              +   ++   +RD  +   ++ +   L+ + +   + E  E P +++ PT +   +L
Sbjct: 1112 QSRSAVRFNHTERDFHTFLQFIANTTGLEANSSVELSQEDYEGP-LSSVPTEETDYLL 942
>04510
          Length = 685

 Score = 48.5 bits (114), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 26/68 (38%), Positives = 36/68 (52%), Gaps = 1/68 (1%)
 Frame = +2

Query: 309 VLALTEKSFEDTIAQ-GITFVKFYAPWCGHCKNLAPTWEELSKKEFPGLSDVTIAEVDCT 367
           VL L +  F+ TI +  +  V+F+APWCGHCK LAP +E  +         V +A+V   
Sbjct: 356 VLDLKKSDFQSTIEKHSLMLVEFFAPWCGHCKKLAPQYELAATALLKNDPPVPLAKVVLC 535

Query: 368 AERNVCSK 375
               VC K
Sbjct: 536 LCYYVCLK 559

 Score = 46.2 bits (108), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 22/47 (46%), Positives = 28/47 (59%), Gaps = 1/47 (2%)
 Frame = +2

Query: 195 FIKFFAPWCGHCKALAPTWEQLALG-LEHSETVKIGKVDCTQHYAVC 240
            ++FFAPWCGHCK LAP +E  A   L++   V + KV     Y VC
Sbjct: 413 LVEFFAPWCGHCKKLAPQYELAATALLKNDPPVPLAKVVLCLCYYVC 553

 Score = 37.7 bits (86), Expect = 0.009,   Method: Compositional matrix adjust.
 Identities = 18/39 (46%), Positives = 23/39 (58%)
 Frame = +2

Query: 67  FVMFFAPWCGHCQRLQPTWNDLGDKYNSMEDAKVYVAKV 105
            V FFAPWCGHC++L P + +L        D  V +AKV
Sbjct: 413 LVEFFAPWCGHCKKLAPQY-ELAATALLKNDPPVPLAKV 526
>14392
          Length = 468

 Score = 48.5 bits (114), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 29/79 (36%), Positives = 45/79 (56%), Gaps = 2/79 (2%)
 Frame = +2

Query: 341 LAPTWEELSKKEFPGLSDVTIAEVDCTAERNVCSKYSVRGYPTLLLF--RGGEKVGEHNG 398
           L P +EEL++K      DV I ++D TA  +V  +++VRG+PTL         K   +NG
Sbjct: 2   LTPIYEELAEKL--QDEDVAIVKMDATA-NDVPPEFNVRGFPTLFWLPKDSKNKPVSYNG 172

Query: 399 GRDLDSLHSFVLRQAKDEL 417
           GR+LD    ++ ++A  EL
Sbjct: 173 GRELDDFIKYIAKEASTEL 229

 Score = 45.1 bits (105), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 29/73 (39%), Positives = 40/73 (54%), Gaps = 2/73 (2%)
 Frame = +2

Query: 209 LAPTWEQLALGLEHSETVKIGKVDCTQHYAVCSEHQVRGYPTLLWF-RDGK-KVDQYKGK 266
           L P +E+LA  L+  E V I K+D T +  V  E  VRG+PTL W  +D K K   Y G 
Sbjct: 2   LTPIYEELAEKLQ-DEDVAIVKMDATAN-DVPPEFNVRGFPTLFWLPKDSKNKPVSYNGG 175

Query: 267 RDLESLRDYVQSQ 279
           R+L+    Y+  +
Sbjct: 176 RELDDFIKYIAKE 214
>15159
          Length = 1945

 Score = 45.8 bits (107), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 27/89 (30%), Positives = 43/89 (48%), Gaps = 2/89 (2%)
 Frame = +3

Query: 174 KQGLYELS-ANNFELHVSQGNHFI-KFFAPWCGHCKALAPTWEQLALGLEHSETVKIGKV 231
           K G+ ++S A++FE  +  G   +  F A WCG CK +AP   + +      ETVKI  V
Sbjct: 72  KMGVIKISSADDFEKAIQGGQLVVVDFHATWCGPCKVIAPKLAKWSEEDRFKETVKIISV 251

Query: 232 DCTQHYAVCSEHQVRGYPTLLWFRDGKKV 260
           D  +   +  E  +   PT  +    K++
Sbjct: 252 DVDELEDLAGEQGISAMPTFFFLEMEKRL 338

 Score = 38.5 bits (88), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 23/80 (28%), Positives = 34/80 (42%), Gaps = 1/80 (1%)
 Frame = +3

Query: 51  LYTADMFTHGIQSAAHFVM-FFAPWCGHCQRLQPTWNDLGDKYNSMEDAKVYVAKVDCTA 109
           + +AD F   IQ     V+ F A WCG C+ + P      ++    E  K+    VD   
Sbjct: 90  ISSADDFEKAIQGGQLVVVDFHATWCGPCKVIAPKLAKWSEEDRFKETVKII--SVDVDE 263

Query: 110 DSDVCSAQGVRGYPTLKFFK 129
             D+   QG+   PT  F +
Sbjct: 264 LEDLAGEQGISAMPTFFFLE 323

 Score = 38.1 bits (87), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 23/87 (26%), Positives = 37/87 (42%), Gaps = 1/87 (1%)
 Frame = +3

Query: 302 PTGDKGTVLALTEKSFEDTIAQG-ITFVKFYAPWCGHCKNLAPTWEELSKKEFPGLSDVT 360
           P+   G +   +   FE  I  G +  V F+A WCG CK +AP   + S+++      V 
Sbjct: 63  PSKKMGVIKISSADDFEKAIQGGQLVVVDFHATWCGPCKVIAPKLAKWSEED-RFKETVK 239

Query: 361 IAEVDCTAERNVCSKYSVRGYPTLLLF 387
           I  VD     ++  +  +   PT    
Sbjct: 240 IISVDVDELEDLAGEQGISAMPTFFFL 320
>36159
          Length = 369

 Score = 45.8 bits (107), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 18/35 (51%), Positives = 27/35 (77%)
 Frame = -1

Query: 72  APWCGHCQRLQPTWNDLGDKYNSMEDAKVYVAKVD 106
           APWCGHC++L P W++LG+K+   +D  V +AK+D
Sbjct: 102 APWCGHCKQLVPIWDELGEKFQDSDD--VVIAKMD 4

 Score = 45.4 bits (106), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 20/34 (58%), Positives = 24/34 (70%)
 Frame = -1

Query: 332 APWCGHCKNLAPTWEELSKKEFPGLSDVTIAEVD 365
           APWCGHCK L P W+EL +K F    DV IA++D
Sbjct: 102 APWCGHCKQLVPIWDELGEK-FQDSDDVVIAKMD 4

 Score = 43.9 bits (102), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 17/33 (51%), Positives = 22/33 (66%)
 Frame = -1

Query: 200 APWCGHCKALAPTWEQLALGLEHSETVKIGKVD 232
           APWCGHCK L P W++L    + S+ V I K+D
Sbjct: 102 APWCGHCKQLVPIWDELGEKFQDSDDVVIAKMD 4
>04779
          Length = 910

 Score = 37.4 bits (85), Expect = 0.013,   Method: Compositional matrix adjust.
 Identities = 18/46 (39%), Positives = 25/46 (54%), Gaps = 4/46 (8%)
 Frame = +1

Query: 359 VTIAEVDCTAERNVCSKYSVRGYPTLLLFRGGEKVG----EHNGGR 400
           V    +D TA +N  ++Y+VRGYPT+  F           E+NGGR
Sbjct: 16  VKFGALDATAHQNKAAEYNVRGYPTIKFFPANSNRASDAQEYNGGR 153

 Score = 37.4 bits (85), Expect = 0.013,   Method: Compositional matrix adjust.
 Identities = 20/70 (28%), Positives = 31/70 (44%), Gaps = 4/70 (5%)
 Frame = +1

Query: 226 VKIGKVDCTQHYAVCSEHQVRGYPTLLWF----RDGKKVDQYKGKRDLESLRDYVQSQLQ 281
           VK G +D T H    +E+ VRGYPT+ +F           +Y G R    +  +   +  
Sbjct: 16  VKFGALDATAHQNKAAEYNVRGYPTIKFFPANSNRASDAQEYNGGRTASDIIAWASDKHT 195

Query: 282 GSEAAPETVE 291
            +   PE +E
Sbjct: 196 ENVPPPELIE 225

 Score = 34.3 bits (77), Expect = 0.10,   Method: Compositional matrix adjust.
 Identities = 19/56 (33%), Positives = 26/56 (46%), Gaps = 4/56 (7%)
 Frame = +1

Query: 98  AKVYVAKVDCTADSDVCSAQGVRGYPTLKFF----KPGQEAVKYQGPRDFETLENW 149
            KV    +D TA  +  +   VRGYPT+KFF        +A +Y G R    +  W
Sbjct: 10  GKVKFGALDATAHQNKAAEYNVRGYPTIKFFPANSNRASDAQEYNGGRTASDIIAW 177
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|13385800|ref|NP_080581.1| transcription elongation
factor B (SIII), polypeptide 2 [Mus musculus]
         (118 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

18844                                                                 135   3e-33
04649                                                                  30   0.28 
34270                                                                  28   1.1  
04017                                                                  28   1.1  
20618                                                                  26   3.2  
00758                                                                  26   3.7  
13455                                                                  26   4.2  
24399                                                                  25   5.5  
03942                                                                  25   9.1  
>18844
          Length = 485

 Score =  135 bits (341), Expect = 3e-33,   Method: Compositional matrix adjust.
 Identities = 65/118 (55%), Positives = 88/118 (74%), Gaps = 2/118 (1%)
 Frame = +3

Query: 1   MDVFLMIRRHKTTIFTDAKESSTVFELKRIVEGILKRPPEEQRLYKDDQ-LLDDGKTLGE 59
           MDVFLMIRR K+TIFTDAKE++ + ++KRI+EGI K  PE QRL++++Q + DD K+LG+
Sbjct: 69  MDVFLMIRRKKSTIFTDAKETTPLIDVKRIIEGIAKVAPENQRLFREEQPMTDDNKSLGD 248

Query: 60  CGFTSQTARPQAPATVGLAFRADD-TFEALRIEPFSSPPELPDVMKPQDSGGSANEQA 116
            G  +  A+ Q+PAT+GL ++ DD  +E L I P SSPPELPDVMKPQ+      +QA
Sbjct: 249 YGLNTNNAKAQSPATLGLVYKKDDGEWETLEIMPLSSPPELPDVMKPQEPAQHVEQQA 422
>04649
          Length = 1590

 Score = 29.6 bits (65), Expect = 0.28,   Method: Compositional matrix adjust.
 Identities = 28/111 (25%), Positives = 54/111 (48%), Gaps = 3/111 (2%)
 Frame = -2

Query: 1   MDVFLMIRRHKTTIFTDAKESSTVFELKRIV---EGILKRPPEEQRLYKDDQLLDDGKTL 57
           M +F+     KT I  + + S T+  +K  +   EGI   PP++QRL    + L+DG+TL
Sbjct: 449 MQIFVKTLTGKT-ITLEVEPSDTIENVKAKIQDKEGI---PPDQQRLIFAGKQLEDGRTL 282

Query: 58  GECGFTSQTARPQAPATVGLAFRADDTFEALRIEPFSSPPELPDVMKPQDS 108
            +          Q  +T+ L  R     +  + + +++P ++ ++ K + S
Sbjct: 281 SDYNI-------QKESTLHLVLRLRGGAKKRKKKNYTTPKKVQNIRKRKSS 150
>34270
          Length = 274

 Score = 27.7 bits (60), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 16/57 (28%), Positives = 30/57 (52%)
 Frame = +1

Query: 13  TIFTDAKESSTVFELKRIVEGILKRPPEEQRLYKDDQLLDDGKTLGECGFTSQTARP 69
           TI  + + S T+  +K  ++     PP++QRL    + L+DG+TL +     ++  P
Sbjct: 67  TITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESHAP 237
>04017
          Length = 690

 Score = 27.7 bits (60), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 25/95 (26%), Positives = 43/95 (45%), Gaps = 3/95 (3%)
 Frame = -1

Query: 13  TIFTDAKESSTVFELKRIV---EGILKRPPEEQRLYKDDQLLDDGKTLGECGFTSQTARP 69
           TI  + + S T+  +K  +   EGI   PP++QRL    + L+DG+TL +          
Sbjct: 309 TITLEVEPSDTIENVKAKIQDKEGI---PPDQQRLIFAGKQLEDGRTLSDYNI------- 160

Query: 70  QAPATVGLAFRADDTFEALRIEPFSSPPELPDVMK 104
           Q  +T+ L  R     +  + E      + P++ K
Sbjct: 159 QKESTLHLVLRLRGGAKKRKEEELHHSQKSPNIRK 55
>20618
          Length = 400

 Score = 26.2 bits (56), Expect = 3.2,   Method: Compositional matrix adjust.
 Identities = 10/27 (37%), Positives = 16/27 (59%)
 Frame = +1

Query: 23  TVFELKRIVEGILKRPPEEQRLYKDDQ 49
           TV+ + +   G + R P  +RLY DD+
Sbjct: 139 TVYTIYKTASGSIVRTPLRRRLYTDDR 219
>00758
          Length = 1050

 Score = 26.2 bits (56), Expect = 3.7,   Method: Compositional matrix adjust.
 Identities = 22/80 (27%), Positives = 38/80 (47%)
 Frame = +1

Query: 1   MDVFLMIRRHKTTIFTDAKESSTVFELKRIVEGILKRPPEEQRLYKDDQLLDDGKTLGEC 60
           M +F+     KT I  + + S T+  +K  ++     PP++QRL    + L+DG+TL + 
Sbjct: 523 MQIFVKTLTGKT-ITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDY 699

Query: 61  GFTSQTARPQAPATVGLAFR 80
                    Q  +T+ L  R
Sbjct: 700 NI-------QKESTLHLVLR 738
>13455
          Length = 809

 Score = 25.8 bits (55), Expect = 4.2,   Method: Compositional matrix adjust.
 Identities = 22/71 (30%), Positives = 35/71 (49%), Gaps = 3/71 (4%)
 Frame = +3

Query: 13  TIFTDAKESSTVFELKRIV---EGILKRPPEEQRLYKDDQLLDDGKTLGECGFTSQTARP 69
           TI  + + S T+  +K  +   EGI   PP++QRL    + L+DG+TL +          
Sbjct: 390 TITLEVEPSDTIENVKAKIQDKEGI---PPDQQRLIFAGKQLEDGRTLSDYNI------- 539

Query: 70  QAPATVGLAFR 80
           Q  +T+ L  R
Sbjct: 540 QKESTLHLVLR 572
>24399
          Length = 1295

 Score = 25.4 bits (54), Expect = 5.5,   Method: Compositional matrix adjust.
 Identities = 15/45 (33%), Positives = 21/45 (46%)
 Frame = +1

Query: 64   SQTARPQAPATVGLAFRADDTFEALRIEPFSSPPELPDVMKPQDS 108
            +Q  R Q  A VGL     D  E + +  FSS P+  + +   DS
Sbjct: 973  NQEIREQIEAAVGLLELTPD*HEMMTVRGFSSKPDCEEAIDRTDS 1107
>03942
          Length = 912

 Score = 24.6 bits (52), Expect = 9.1,   Method: Compositional matrix adjust.
 Identities = 21/62 (33%), Positives = 34/62 (54%), Gaps = 3/62 (4%)
 Frame = +1

Query: 1   MDVFLMIRRHKTTIFTDAKESSTVFELK---RIVEGILKRPPEEQRLYKDDQLLDDGKTL 57
           M +F+     KT I  + + S T+  +K   +  EGI   PP++QRL    + L+DG+TL
Sbjct: 406 MQIFVKTLTGKT-ITLEVEPSDTIENVKAKSKDKEGI---PPDQQRLIFAGKQLEDGRTL 573

Query: 58  GE 59
            +
Sbjct: 574 SD 579
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31981160|ref|NP_080116.2| basic leucine zipper and W2
domains 2 [Mus musculus]
         (419 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

14553                                                                 139   3e-33
01971                                                                 130   1e-30
16157                                                                  37   0.014
14839                                                                  35   0.049
04759                                                                  34   0.11 
16948                                                                  30   2.1  
25360                                                                  30   2.6  
11089                                                                  30   2.6  
>14553
          Length = 465

 Score =  139 bits (349), Expect = 3e-33,   Method: Compositional matrix adjust.
 Identities = 63/122 (51%), Positives = 91/122 (74%)
 Frame = -2

Query: 2   NKHQKPVLTGQRFKTRKRDEKEKFEPTVFRDTLVQGLNEAGDDLEAVAKFLDSTGSRLDY 61
           +K++K    G   + +KRDE+EK++PT FRD ++ GL +   DL+ ++K+LDS G++LDY
Sbjct: 365 SKNRKTSAIGSTHQDQKRDEREKYDPTGFRDAVIAGLEKTEGDLDQISKYLDSAGNKLDY 186

Query: 62  RRYADTLFDILVAGSMLAPGGTRIDDGDKTKMTNHCVFSANEDHETIRNYAQVFNKLIRR 121
           RRY + LFDIL+AG +L PGG+   DG+K + TN+C+F A ED E++RN+ QVF KLIRR
Sbjct: 185 RRYGEVLFDILIAGGLLVPGGSISQDGEKPR-TNYCIFDAPEDMESMRNHEQVFVKLIRR 9

Query: 122 YK 123
           YK
Sbjct: 8   YK 3
>01971
          Length = 1169

 Score =  130 bits (326), Expect = 1e-30,   Method: Compositional matrix adjust.
 Identities = 55/89 (61%), Positives = 74/89 (83%)
 Frame = +1

Query: 317 QALKHLKQYAPLLAVFSSQGQSELVLLQKVQEYCYDNIHFMKAFQKIVVLFYKADVLSEE 376
           QA+KHL+ Y  LLA  +   ++EL L+ +VQEYCY+N++F+K+FQKI+++ YK DVLSEE
Sbjct: 1   QAMKHLRMYTSLLATTAKSARAELALMLRVQEYCYENMNFLKSFQKIIIMLYKTDVLSEE 180

Query: 377 AILKWYKEAHAAKGKSVFLDQMKKFVEWL 405
            IL+WYK+AH+ KGKSVFLDQMK FV+WL
Sbjct: 181 TILRWYKQAHSPKGKSVFLDQMKTFVDWL 267
>16157
          Length = 1330

 Score = 37.0 bits (84), Expect = 0.014,   Method: Compositional matrix adjust.
 Identities = 58/254 (22%), Positives = 101/254 (39%), Gaps = 24/254 (9%)
 Frame = -1

Query: 179  KEGIAASFAVKLFKAWMAEKDANSVTSSLRKANLDKRLLELFPVNRQSVDHFAKYFTDAG 238
            + G+     +   +A    KD   +T     + LD  L+ + P   Q  +   +   D G
Sbjct: 1327 QHGVHYPLFLLCLQAAHRVKDKQWLTRVFSDSKLD--LITMLPEIDQKKEKLLEILEDRG 1154

Query: 239  LKELSDFLRVQQSLGTRKELQKELQERLSQECPIKEVVLYVKEEMKRNDLPETAVIGLLW 298
            L  L   +RVQ  LG            ++ E        ++K+ +  +       I +L 
Sbjct: 1153 LSFLFPLMRVQSELG----------RHIAAEPTASATFKWIKDHVDPDLFTNPKFIHIL- 1007

Query: 299  TCIMNAVEWNKKEELVAEQALKHLKQYAPLLAVFSSQGQSELV-----LLQK-------- 345
              + + V++   E  +AE         AP  A  +S  + EL+     +LQK        
Sbjct: 1006 --VTSVVKYITSESTLAENVDS---SAAPDKA--ASDKEKELLDKLKGVLQKFLHEHLSL 848

Query: 346  -------VQEYCYDNIHFMKA-FQKIVVLFYKADVLSEEAILKWYKEAH---AAKGKSVF 394
                   VQ +C+ + HF K    +  V  Y  +++ EEA L W +E +     KGK +F
Sbjct: 847  QVSALYAVQVFCHSH-HFPKGMLLRFFVNLYDQEIIEEEAFLHWKEEVNDEFPGKGKXLF 671

Query: 395  LDQMKKFVEWLQNA 408
              Q+ +++ WL+ A
Sbjct: 670  --QVNQWLTWLEQA 635
>14839
          Length = 340

 Score = 35.4 bits (80), Expect = 0.049,   Method: Compositional matrix adjust.
 Identities = 23/70 (32%), Positives = 39/70 (55%), Gaps = 4/70 (5%)
 Frame = +3

Query: 343 LQKVQEYCYDNIHFMKA-FQKIVVLFYKADVLSEEAILKWYKEAH---AAKGKSVFLDQM 398
           L  VQ +C+ + HF K    +  V  Y  +++ EEA L W +E +     KGK++F  Q+
Sbjct: 27  LYAVQVFCHSH-HFPKGMLLRFFVNLYDQEIIEEEAFLHWKEEVNDEFPGKGKALF--QV 197

Query: 399 KKFVEWLQNA 408
            +++ WL+ A
Sbjct: 198 NQWLTWLEQA 227
>04759
          Length = 2827

 Score = 34.3 bits (77), Expect = 0.11,   Method: Compositional matrix adjust.
 Identities = 50/213 (23%), Positives = 87/213 (40%), Gaps = 24/213 (11%)
 Frame = +2

Query: 209  KANLDKRLLELFPVNRQSVDHFAKYFTDAGLKELSDFLRVQQSLGTRKELQKELQERLSQ 268
            ++NL+  L ++ P   Q  +   +   D GL  L   LRVQ  LG           +++ 
Sbjct: 2009 QSNLN--LQDMLPEIDQKKERMMEILEDRGLSFLFPLLRVQSELG----------RQIAA 2152

Query: 269  ECPIKEVVLYVKEEMKRNDLPETAVIGLLWTCIMNAVEWNKKEELVAEQALKHLKQYAPL 328
            E     +  ++KE +  +       I +L   +   V++   E  +AE A  ++     L
Sbjct: 2153 EPSAGAIFKWIKERVDPDLFANPNFINIL---VAGVVKYITGESTLAENADPNVTPDKSL 2323

Query: 329  LAVFSSQGQSELV-----LLQK---------------VQEYCYDNIHFMKA-FQKIVVLF 367
            +       + EL+     +LQK               VQ +C+ + HF K    +  V  
Sbjct: 2324 M-----DKEKELLDKLKGVLQKFLHEHIDLQVSALYAVQVFCHSH-HFPKGMLLRFFVNL 2485

Query: 368  YKADVLSEEAILKWYKEA---HAAKGKSVFLDQ 397
            Y  +++ EEA L W +E    +  KGK++F  Q
Sbjct: 2486 YDQEIVEEEAFLHWKEEVNDQYPGKGKALFRGQ 2584
>16948
          Length = 1465

 Score = 30.0 bits (66), Expect = 2.1,   Method: Compositional matrix adjust.
 Identities = 17/57 (29%), Positives = 25/57 (43%), Gaps = 4/57 (7%)
 Frame = +3

Query: 356 FMKAFQKIVVLFYKADVLSEEAILKWYKEAHAAKGKSVFLDQM----KKFVEWLQNA 408
            M     ++  FY  D+L EE I+ W K+            QM    K F++WL+ A
Sbjct: 15  LMPRVPHVLKTFYDLDILDEEIIIDWAKKMSKKYVSKEIAQQMREKAKPFIDWLEQA 185
>25360
          Length = 751

 Score = 29.6 bits (65), Expect = 2.6,   Method: Compositional matrix adjust.
 Identities = 11/21 (52%), Positives = 15/21 (71%)
 Frame = -1

Query: 63  RYADTLFDILVAGSMLAPGGT 83
           R+  T F +L+ GSM APGG+
Sbjct: 331 RHGPTTFAVLLTGSMTAPGGS 269
>11089
          Length = 1213

 Score = 29.6 bits (65), Expect = 2.6,   Method: Compositional matrix adjust.
 Identities = 11/21 (52%), Positives = 15/21 (71%)
 Frame = +3

Query: 63   RYADTLFDILVAGSMLAPGGT 83
            R+  T F +L+ GSM APGG+
Sbjct: 1065 RHGPTTFAVLLTGSMTAPGGS 1127
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|37718983|ref|NP_937806.1| RAB35, member RAS oncogene
family [Mus musculus]
         (201 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

34468                                                                 137   3e-33
08428                                                                 132   1e-31
33374                                                                  94   1e-26
05468                                                                 114   2e-26
07465                                                                 111   2e-25
26083                                                                 107   4e-24
14456                                                                 100   5e-22
33794                                                                  99   1e-21
17511                                                                  99   1e-21
13901                                                                  95   2e-20
01972                                                                  80   7e-19
30760                                                                  89   9e-19
19006                                                                  86   1e-17
32723                                                                  84   3e-17
33380                                                                  82   3e-17
11728                                                                  82   1e-16
11257                                                                  82   1e-16
01398                                                                  81   2e-16
35581                                                                  79   8e-16
13750                                                                  79   2e-15
19656                                                                  77   3e-15
07580                                                                  74   6e-14
26536                                                                  67   4e-12
27191                                                                  66   1e-11
34359                                                                  66   1e-11
00858                                                                  65   2e-11
09204                                                                  63   1e-10
12339                                                                  62   1e-10
13745                                                                  60   7e-10
01095                                                                  55   2e-08
29380                                                                  54   3e-08
34597                                                                  54   4e-08
00552                                                                  51   4e-07
08153                                                                  50   5e-07
10708                                                                  39   7e-07
09827                                                                  50   8e-07
33605                                                                  48   3e-06
31291                                                                  47   4e-06
10862                                                                  44   3e-05
14775                                                                  43   1e-04
25796                                                                  39   0.001
31928                                                                  35   0.027
09700                                                                  32   0.12 
>34468
          Length = 1502

 Score =  137 bits (345), Expect = 3e-33,   Method: Compositional matrix adjust.
 Identities = 70/150 (46%), Positives = 97/150 (64%), Gaps = 3/150 (2%)
 Frame = +1

Query: 8   LFKLLIIGDSGVGKSSLLLRFADNTFSGSYITTIGVDFKIRTVEINGEKVKLQIWDTAGQ 67
           +FK+++IGDS VGK+ L  RF    F      TIGVDF+ ++++++ E +KLQ+WDTAGQ
Sbjct: 493 IFKIIVIGDSNVGKTCLTYRFCLGKFPDKTEATIGVDFREKSIQVDSEHLKLQLWDTAGQ 672

Query: 68  ERFR-TITSTYYRGTHGVIVVYDVTSAESFVNVKRWLHEINQN--CDDVCRILVGNKNDD 124
           ERFR ++   YYR  H V+ VYD+T   SF N+  W+ E +++     + RILVGNK D 
Sbjct: 673 ERFRKSMVQHYYRNVHAVVFVYDMTKMSSFENMPAWIEECDRHNLTKYIPRILVGNKCDV 852

Query: 125 PERKVVETEDAYKFAGQMGIQLFETSAKEN 154
            ER  V T  A KFA    + LFETSAK++
Sbjct: 853 VERIAVNTNLAQKFADAHNMPLFETSAKDD 942
>08428
          Length = 1109

 Score =  132 bits (331), Expect = 1e-31,   Method: Compositional matrix adjust.
 Identities = 67/160 (41%), Positives = 97/160 (60%), Gaps = 1/160 (0%)
 Frame = -3

Query: 10   KLLIIGDSGVGKSSLLLRFADNTFSGSYITTIGVDFKIRTVEINGEKVKLQIWDTAGQER 69
            K+ ++GDSGVGKSS++LRF   ++  S  +TIG  F  +++ ++G   + QIWDTAGQE+
Sbjct: 1065 KVCLLGDSGVGKSSIVLRFVTGSYRPSQESTIGASFMSKSLVVDGAGYRFQIWDTAGQEK 886

Query: 70   FRTITSTYYRGTHGVIVVYDVTSAESFVNVKRWLHEINQ-NCDDVCRILVGNKNDDPERK 128
            FR +   YYRG    ++VYDVT   +F +VK W+ E+      ++   + GNK D  E +
Sbjct: 885  FRALAPMYYRGAAAAVIVYDVTRPRTFKSVKSWIQELRSFGPPNIVLAIAGNKCDLEELR 706

Query: 129  VVETEDAYKFAGQMGIQLFETSAKENVNVEEMFNCITELV 168
             V  +DA ++A  +     ETSA   VNVEEMF   TEL 
Sbjct: 705  EVVEKDAQEYASSISAIFGETSAMTAVNVEEMF---TELA 595
>33374
          Length = 489

 Score = 94.4 bits (233), Expect(2) = 1e-26,   Method: Compositional matrix adjust.
 Identities = 46/117 (39%), Positives = 71/117 (60%), Gaps = 1/117 (0%)
 Frame = +1

Query: 45  FKIRTVEINGEKVKLQIWDTAGQERFRTITSTYYRGTHGVIVVYDVTSAESFVNVKRWLH 104
           F  +TV ++   VK +IWDTAGQER+ ++   YYRG    IVVYD+T+ ++F   K W+ 
Sbjct: 139 FLTQTVCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNQDTFGRAKTWVK 318

Query: 105 EIN-QNCDDVCRILVGNKNDDPERKVVETEDAYKFAGQMGIQLFETSAKENVNVEEM 160
           E+  Q   ++   L GNK D   +++VE E+A  +A +  +   ETSAK  +NV ++
Sbjct: 319 ELQRQASPNIVIALAGNKADLANKRMVEFEEAQAYAEENSLLFMETSAKTAMNVNDI 489

 Score = 42.0 bits (97), Expect(2) = 1e-26,   Method: Compositional matrix adjust.
 Identities = 20/40 (50%), Positives = 27/40 (67%)
 Frame = +2

Query: 9  FKLLIIGDSGVGKSSLLLRFADNTFSGSYITTIGVDFKIR 48
          FKL+++G+S VGKSSL+LRF    F     +TIG  F +R
Sbjct: 32 FKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAF*LR 151
>05468
          Length = 1558

 Score =  114 bits (285), Expect = 2e-26,   Method: Compositional matrix adjust.
 Identities = 62/162 (38%), Positives = 98/162 (60%), Gaps = 8/162 (4%)
 Frame = -3

Query: 6    DHLFKLLIIGDSGVGKSSLLLRFADNTFSGSYITTIGVDFKIRTVEINGEK-VKLQIWDT 64
            +HL+K+L+IG+ G GK+S++ R+    FS  Y  TIGVDF ++ +  + +  ++LQ+WD 
Sbjct: 1547 EHLYKILVIGELGTGKTSIIKRYVHQFFSQHYRATIGVDFALKVLNWDADTLIRLQLWDI 1368

Query: 65   AGQERFRTITSTYYRGTHGVIVVYDVTSAESFVNVKRWLHEINQNC-----DDVCRILVG 119
            AGQERF  +T  YY+   G  VV+DVT A +F  V +W ++++          V  +L+ 
Sbjct: 1367 AGQERFGNMTRVYYKEAVGAFVVFDVTRASTFDAVTKWKNDLDSKVQLADGSPVPCVLLA 1188

Query: 120  NKNDDPERKVV-ETEDAYKFAGQMG-IQLFETSAKENVNVEE 159
            NK D  +  +V  T    +F  + G I  +ETSAKEN+N++E
Sbjct: 1187 NKCDQAKEGLVNNTSQMDEFCSEKGFIGWYETSAKENINIDE 1062
>07465
          Length = 1103

 Score =  111 bits (277), Expect = 2e-25,   Method: Compositional matrix adjust.
 Identities = 53/148 (35%), Positives = 85/148 (57%)
 Frame = +3

Query: 22  SSLLLRFADNTFSGSYITTIGVDFKIRTVEINGEKVKLQIWDTAGQERFRTITSTYYRGT 81
           SS++ R+    F+  Y  TIGVDF  R +E+ GE V+L +WDTAGQE F  IT  YYRG 
Sbjct: 240 SSMIQRYCKGIFTKDYKKTIGVDFLERQIEVGGEDVRLMLWDTAGQEEFDAITKAYYRGA 419

Query: 82  HGVIVVYDVTSAESFVNVKRWLHEINQNCDDVCRILVGNKNDDPERKVVETEDAYKFAGQ 141
              ++ +     +SF  ++ W  ++     ++  ++V NK D  +  VV  E+A   A +
Sbjct: 420 QACVLAFSTVDRDSFEALETWKRKVEDEVGEIGMVIVQNKIDLIDDAVVRPEEAENLAKK 599

Query: 142 MGIQLFETSAKENVNVEEMFNCITELVL 169
           + ++ + TS KEN+NV+E+F  + +  L
Sbjct: 600 LRLRFYRTSVKENMNVDEVFRYLADKYL 683
>26083
          Length = 432

 Score =  107 bits (266), Expect = 4e-24,   Method: Compositional matrix adjust.
 Identities = 49/114 (42%), Positives = 77/114 (67%), Gaps = 1/114 (0%)
 Frame = +1

Query: 9   FKLLIIGDSGVGKSSLLLRFADNTFSGSYITTIGVDFKIRTVEINGEKVKLQIWDTAGQE 68
           FKL+ +G+  VGK+SL+ RF  ++F  +Y  TIG+DF  +T+ +    ++LQ+WDTAGQE
Sbjct: 79  FKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTIRLQLWDTAGQE 258

Query: 69  RFRTITSTYYRGTHGVIVVYDVTSAESFVNVKRWLHEI-NQNCDDVCRILVGNK 121
           RFR++  +Y R +   +VVYD+T+A SF    +W+ ++  +   DV  +LVGNK
Sbjct: 259 RFRSLIPSYIRDSSVAVVVYDITNANSFHQTSKWIDDVRTERGSDVIIMLVGNK 420
>14456
          Length = 1867

 Score =  100 bits (248), Expect = 5e-22,   Method: Compositional matrix adjust.
 Identities = 57/149 (38%), Positives = 79/149 (53%), Gaps = 5/149 (3%)
 Frame = -1

Query: 18   GVGKSSLLLRFADNTFSGSYITTIGVDFKIRTVEINGEKVKLQIWDTAGQERFRTITSTY 77
            GVGKSSL+ RF  N F      TIGV+F  + V ++ E   +QIWDTAGQERF+++ + +
Sbjct: 1111 GVGKSSLMNRFVSNKFDAQSFHTIGVEFLNKDVVVDDETYTMQIWDTAGQERFKSLRTPF 932

Query: 78   YRGTHGVIVVYDVTSAESFVNVKRWLHEINQNCD-----DVCRILVGNKNDDPERKVVET 132
            YRG    ++ + V S +SF N+  W  E     D         +++GNK D   R+V   
Sbjct: 931  YRGADCCLLTFSVDSMQSFRNLSMWRKEFLYYADIQDGVTFPFVVLGNKIDVEGRQVTNE 752

Query: 133  EDAYKFAGQMGIQLFETSAKENVNVEEMF 161
            E             FETSAK+  NVE+ F
Sbjct: 751  EARSWCTANSNAPYFETSAKDATNVEKAF 665
>33794
          Length = 779

 Score = 99.0 bits (245), Expect = 1e-21,   Method: Compositional matrix adjust.
 Identities = 47/127 (37%), Positives = 76/127 (59%)
 Frame = -1

Query: 43  VDFKIRTVEINGEKVKLQIWDTAGQERFRTITSTYYRGTHGVIVVYDVTSAESFVNVKRW 102
           V +K  T+ + G++VKLQIWDT+GQ RF TI  +Y RG  G+I+VYD+T+  SF  + RW
Sbjct: 692 VAYKTTTILLEGKRVKLQIWDTSGQGRFCTIIRSYSRGAQGIILVYDITNKWSFDGIDRW 513

Query: 103 LHEINQNCDDVCRILVGNKNDDPERKVVETEDAYKFAGQMGIQLFETSAKENVNVEEMFN 162
           L E+ ++   + ++LVGN+     ++ V  + A  +A +  +  FE S   + N+ E F 
Sbjct: 512 LKEVEEHAPGIPKVLVGNRLHLAYKRQVAAKQAETYASRNNMSCFEISPLCDFNIRESFC 333

Query: 163 CITELVL 169
            +  + L
Sbjct: 332 ELARMAL 312
>17511
          Length = 483

 Score = 98.6 bits (244), Expect = 1e-21,   Method: Compositional matrix adjust.
 Identities = 49/128 (38%), Positives = 78/128 (60%), Gaps = 5/128 (3%)
 Frame = -3

Query: 1   MARDYDHLFKLLIIGDSGVGKSSLLLRFADNTFSGSYITTIGVDFKIRTVEINGEKVKLQ 60
           MA     L K++I+GDSGVGK+SL+ ++ +  FS  Y  TIG DF  + V ++   V +Q
Sbjct: 388 MASRKKVLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQ 209

Query: 61  IWDTAGQERFRTITSTYYRGTHGVIVVYDVTSAESFVNVKRWLHEI-----NQNCDDVCR 115
           IWDTAGQERF+++   +YRG    ++V+DVT   +F ++  W  E       ++ ++   
Sbjct: 208 IWDTAGQERFQSLGVAFYRGADCCVLVFDVTMPNTFRSLDSWRDEFLIQASPRDPENFPF 29

Query: 116 ILVGNKND 123
           +++GNK D
Sbjct: 28  VVIGNKID 5
>13901
          Length = 962

 Score = 95.1 bits (235), Expect = 2e-20,   Method: Compositional matrix adjust.
 Identities = 42/96 (43%), Positives = 65/96 (67%), Gaps = 1/96 (1%)
 Frame = -3

Query: 8   LFKLLIIGDSGVGKSSLLLRFADNTFSGSYITTIGVDFKIRTVEINGE-KVKLQIWDTAG 66
           LFK++IIGD  VGK+S + R+ +++F   Y  TIGVDF ++ +  + +  +KLQ+WD AG
Sbjct: 288 LFKVIIIGDPTVGKTSFVQRYVNDSFRRDYKMTIGVDFALKVIRWSDKCNIKLQLWDIAG 109

Query: 67  QERFRTITSTYYRGTHGVIVVYDVTSAESFVNVKRW 102
           QERF ++T  YY+  H  IV++D+T   ++ N  RW
Sbjct: 108 QERFTSMTRVYYKDAHACIVMFDLTQKNTYQNAIRW 1
>01972
          Length = 2359

 Score = 80.5 bits (197), Expect(2) = 7e-19,   Method: Compositional matrix adjust.
 Identities = 42/125 (33%), Positives = 69/125 (55%)
 Frame = +3

Query: 37  YITTIGVDFKIRTVEINGEKVKLQIWDTAGQERFRTITSTYYRGTHGVIVVYDVTSAESF 96
           Y+ T+GV+        +  K+K  +WDTAGQE+F  +   YY      ++++DVTS  ++
Sbjct: 387 YVATLGVEVHPLLFHTSRGKLKFNVWDTAGQEKFGGLRDGYYIQGQCAVIMFDVTSRVTY 566

Query: 97  VNVKRWLHEINQNCDDVCRILVGNKNDDPERKVVETEDAYKFAGQMGIQLFETSAKENVN 156
            NV  W  ++ + C+++  +L GNK D  +RKV     A  F  +  +Q ++ SAK N N
Sbjct: 567 KNVPNWHRDLVRVCENIPIVLCGNKVDIKDRKV--KAKAIVFHRKKNLQYYDISAKSNYN 740

Query: 157 VEEMF 161
            E+ F
Sbjct: 741 FEKPF 755

 Score = 29.6 bits (65), Expect(2) = 7e-19,   Method: Compositional matrix adjust.
 Identities = 11/36 (30%), Positives = 21/36 (58%)
 Frame = +1

Query: 4   DYDHLFKLLIIGDSGVGKSSLLLRFADNTFSGSYIT 39
           + +  FKL+++GD GVGK++ + R     F  + + 
Sbjct: 289 EQEPTFKLVLVGDGGVGKTTFVKRHVTGEFEKNMLP 396
>30760
          Length = 596

 Score = 89.4 bits (220), Expect = 9e-19,   Method: Compositional matrix adjust.
 Identities = 56/162 (34%), Positives = 88/162 (54%), Gaps = 6/162 (3%)
 Frame = -1

Query: 10  KLLIIGDSGVGKSSLLLRFADNT--FSGSYITTIGVDFKIRTVEI--NGEKVKLQIWDTA 65
           K ++ GDSGVGKSS+   F  ++  F  +Y  T GV+  ++ V I  + ++V+L ++D+A
Sbjct: 524 KCIVTGDSGVGKSSICQVFHSDSAHFPKNYSMTTGVEVLVKLVNIPDSRDQVELYLFDSA 345

Query: 66  GQERFRTITSTYYRGTHGVIVVYDVTSAESFVNVKRWLHEINQNCDD--VCRILVGNKND 123
           G+E F    + ++     V+VVYDVT   SF    RWL  +     +  +  +LV NK D
Sbjct: 344 GKEIFSENVTKFWDQPSVVMVVYDVTDETSFSGCVRWLERVRAAKPNTVIPGVLVANKTD 165

Query: 124 DPERKVVETEDAYKFAGQMGIQLFETSAKENVNVEEMFNCIT 165
             ER+ V  ++    A   G++ FE SAKE  N +  F C+ 
Sbjct: 164 LDERRRVSRKEGKDLAQSHGLEYFECSAKEMQNTDTPFFCLA 39
>19006
          Length = 568

 Score = 85.5 bits (210), Expect = 1e-17,   Method: Compositional matrix adjust.
 Identities = 40/118 (33%), Positives = 71/118 (60%), Gaps = 1/118 (0%)
 Frame = -2

Query: 7   HLFKLLIIGDSGVGKSSLLLRFADNTFSGSYITTIGVDFKIRTVEINGEKVKLQIWDTAG 66
           H  KL+I+GD   GK+ LL+ F+ + F   Y+ T+  ++ +  +E++ ++V+L +WDTAG
Sbjct: 441 HKEKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENY-VADIEVDSKQVELALWDTAG 265

Query: 67  QERFRTITSTYYRGTHGVIVVYDVTSAESFVNV-KRWLHEINQNCDDVCRILVGNKND 123
           QE +  +    Y  T  +++ + + S +S  N+ ++W  E+   C +V  ILVGNK D
Sbjct: 264 QEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVRHFCPNVPIILVGNKKD 91
>32723
          Length = 384

 Score = 84.3 bits (207), Expect = 3e-17,   Method: Compositional matrix adjust.
 Identities = 42/100 (42%), Positives = 64/100 (64%), Gaps = 1/100 (1%)
 Frame = +2

Query: 67  QERFRTITSTYYRGTHGVIVVYDVTSAESFVNVKRWLHEINQNC-DDVCRILVGNKNDDP 125
           QERFR+IT +YYR  + +I+VYDV S +S+ ++ +W+HEI       V   LVGNK D  
Sbjct: 2   QERFRSITQSYYRSANALILVYDVCSQQSYESLPQWIHEIELYAGTKVLAFLVGNKIDQT 181

Query: 126 ERKVVETEDAYKFAGQMGIQLFETSAKENVNVEEMFNCIT 165
           +++ + T    +FA +  ++  ETSAKE  NVE++F+ I 
Sbjct: 182 DKREIPTHIGKEFAERYEMRFLETSAKEADNVEKLFSTIA 301
>33380
          Length = 282

 Score = 81.6 bits (200), Expect(2) = 3e-17,   Method: Compositional matrix adjust.
 Identities = 43/82 (52%), Positives = 57/82 (69%), Gaps = 1/82 (1%)
 Frame = +3

Query: 49  TVEINGEKVKLQIWDTAGQERFRTITSTYYRGTHGVIVVYDVTSAESFVNVKRWLHEINQ 108
           TV    ++VKLQIWDTAGQER+RTIT+ YYRG  G I++YDVT+ ESF  V+ W  +I  
Sbjct: 36  TVFRQDKRVKLQIWDTAGQERYRTITTAYYRGAMGFILMYDVTNEESFNAVQDWCTQIKT 215

Query: 109 -NCDDVCRILVGNKNDDPERKV 129
            + D+   +LVGNK D  + +V
Sbjct: 216 YSWDNAQVVLVGNKCDLEDERV 281

 Score = 23.1 bits (48), Expect(2) = 3e-17,   Method: Compositional matrix adjust.
 Identities = 5/15 (33%), Positives = 14/15 (93%)
 Frame = +2

Query: 37 YITTIGVDFKIRTVE 51
          +++T+G+DFK+ +++
Sbjct: 2  FVSTVGIDFKVNSLQ 46
>11728
          Length = 635

 Score = 82.4 bits (202), Expect = 1e-16,   Method: Compositional matrix adjust.
 Identities = 41/116 (35%), Positives = 64/116 (55%), Gaps = 1/116 (0%)
 Frame = -1

Query: 9   FKLLIIGDSGVGKSSLLLRFADNTFSGSYITTIGVDFKIRTVEINGEKVKLQIWDTAGQE 68
            K +++GD  VGK+ LL+ +  N F G YI T+  D     V ++ + + L +WDTAGQE
Sbjct: 488 IKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTV-FDNYSANVMVDSKPINLGLWDTAGQE 312

Query: 69  RFRTITSTYYRGTHGVIVVYDVTSAESFVNVK-RWLHEINQNCDDVCRILVGNKND 123
            +  +    Y  T   ++ + + S  SF NVK +W  E++ +C +   ILVG K D
Sbjct: 311 DYDRLRPLSYPQTDVFLICFSLISPASFENVKAKWYPEVSHHCPNTPIILVGTKLD 144
>11257
          Length = 1102

 Score = 82.0 bits (201), Expect = 1e-16,   Method: Compositional matrix adjust.
 Identities = 44/120 (36%), Positives = 75/120 (62%), Gaps = 6/120 (5%)
 Frame = -2

Query: 48   RTVEINGEKVKLQIWDTAGQERFRTITSTYYRGTHGVIVVYDVTSAESFVNVKRWLHE-I 106
            + V ++GE   +QIWDTAGQER++++ + +YRGT   ++ + V + +S  ++  W  E +
Sbjct: 1053 KDVVVDGETFTMQIWDTAGQERYKSLRTPFYRGTDCCLLTFSVDNLKSLQSLSDWYDEFV 874

Query: 107  N----QNCDDVCRILVGNKNDDPERKVVETEDAYKFAGQMG-IQLFETSAKENVNVEEMF 161
            N    Q+      +++GNK D  ER+ V +EDAY +    G +  FETSAK+++NV++ F
Sbjct: 873  NYADIQDSASFPFVIIGNKADIEERE-VSSEDAYNWCRTHGNLPYFETSAKDSLNVQQAF 697
>01398
          Length = 1421

 Score = 81.3 bits (199), Expect = 2e-16,   Method: Compositional matrix adjust.
 Identities = 39/102 (38%), Positives = 64/102 (62%), Gaps = 2/102 (1%)
 Frame = -2

Query: 67   QERFRTITSTYYRGTHGVIVVYDVTSAESFVNVKRWLHEINQNCDD--VCRILVGNKNDD 124
            QERFR+IT +YYR + GVI+VYD+T   +F N+K+W  E   + +      +++G+K+D 
Sbjct: 1420 QERFRSITRSYYRNSVGVIIVYDITKRSTFENLKQWYEEARNHIEPHKAIFLVLGHKSDR 1241

Query: 125  PERKVVETEDAYKFAGQMGIQLFETSAKENVNVEEMFNCITE 166
             + + V   +  +FA   G++ FETSAK   N+E++F  I +
Sbjct: 1240 EDARQVTAREGRRFAEMHGLKFFETSAKSGHNIEDVFAQIAK 1115
>35581
          Length = 364

 Score = 79.3 bits (194), Expect = 8e-16,   Method: Compositional matrix adjust.
 Identities = 40/95 (42%), Positives = 62/95 (65%), Gaps = 1/95 (1%)
 Frame = +2

Query: 9   FKLLIIGDSGVGKSSLLLRFADNTFSGSYITTIGVDFKIRTVEI-NGEKVKLQIWDTAGQ 67
           FK +++GD+GVGK+ LL R A + F  S +T++     + TV + +G    + +WDTAGQ
Sbjct: 47  FKCVLLGDAGVGKTCLLNRLATDKFLDSPLTSLTTASLLTTVTLTSGVMASVDLWDTAGQ 226

Query: 68  ERFRTITSTYYRGTHGVIVVYDVTSAESFVNVKRW 102
           ER+R++TS+YYR T  V++VYD   AE  + +  W
Sbjct: 227 ERYRSLTSSYYRDTKAVLIVYD---AEHKLKLTDW 322
>13750
          Length = 503

 Score = 78.6 bits (192), Expect = 2e-15,   Method: Compositional matrix adjust.
 Identities = 52/155 (33%), Positives = 80/155 (51%), Gaps = 5/155 (3%)
 Frame = -2

Query: 21  KSSLLLRFADNTFSGSYITTIGV---DF-KIRTVEINGEKVKLQIWDTAGQERFRTITST 76
           K+ LL R+    F    + TI V   +F + RT  +N   V+  +WDT G E +R++  +
Sbjct: 502 KTCLLRRYQKGFFMDRTMPTIAVLCSEFNESRTDPLN---VRYTLWDTGGAETYRSLWVS 332

Query: 77  YYRGTHGVIVVYDVTSAESFVNVKR-WLHEINQNCDDVCRILVGNKNDDPERKVVETEDA 135
           ++RG    ++VYDVT   SF+     W   + +N  +   I VG+K D  E +V+ TE  
Sbjct: 331 HFRGAQVALLVYDVTCEWSFLTATTVWRKALMKNIPEAQVIFVGSKTDLEENRVISTERG 152

Query: 136 YKFAGQMGIQLFETSAKENVNVEEMFNCITELVLR 170
             FA Q G   FETS+    NV+ +F  I  ++ R
Sbjct: 151 QAFATQCGYTFFETSSVTGKNVDAVFWEIAFILAR 47
>19656
          Length = 428

 Score = 77.4 bits (189), Expect = 3e-15,   Method: Compositional matrix adjust.
 Identities = 37/102 (36%), Positives = 57/102 (55%), Gaps = 1/102 (0%)
 Frame = +3

Query: 10  KLLIIGDSGVGKSSLLLRFADNTFSGSYITTIGVDFKIRTVEINGEKVKLQIWDTAGQER 69
           K +++GD  VGK+ LL+ +  N F G YI T+  D     V ++G  V L +WDTAGQE 
Sbjct: 117 KCVVVGDGAVGKTCLLISYTTNAFPGEYIPTV-FDNYSANVMVDGRPVNLGLWDTAGQED 293

Query: 70  FRTITSTYYRGTHGVIVVYDVTSAESFVNVK-RWLHEINQNC 110
           +  +    Y  T   ++ + V S  SF N++ +W  E+N +C
Sbjct: 294 YDRLRPLSYPQTDVFLLCFSVASPASFENIRAKWYPEVNHHC 419
>07580
          Length = 921

 Score = 73.6 bits (179), Expect = 6e-14,   Method: Compositional matrix adjust.
 Identities = 42/131 (32%), Positives = 70/131 (53%), Gaps = 2/131 (1%)
 Frame = +3

Query: 33  FSGSYITTIGVDFKIRTVEINGEKVKLQIWDTAGQERFRTITSTYYRGTHGVIVVYDVTS 92
           F   Y  TI   ++ + VE++G++  L+I DTAG E+F  +   Y +   G ++ Y +T+
Sbjct: 135 FVEKYDPTIEDSYR-KQVEVDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFLLAYSITA 311

Query: 93  AESFVNVKRWLHEI--NQNCDDVCRILVGNKNDDPERKVVETEDAYKFAGQMGIQLFETS 150
             +F +++    +I   ++ DDV  +LVGNK D  + +VV  +     A        ETS
Sbjct: 312 QSTFNDLQELREQILRVKDTDDVPMLLVGNKCDLEDERVVGKDQGQGLARSFSCAFLETS 491

Query: 151 AKENVNVEEMF 161
           AK  +NV E+F
Sbjct: 492 AKARINVNEIF 524
>26536
          Length = 829

 Score = 67.4 bits (163), Expect = 4e-12,   Method: Compositional matrix adjust.
 Identities = 41/118 (34%), Positives = 60/118 (50%), Gaps = 3/118 (2%)
 Frame = +2

Query: 56  KVKLQIWDTAGQERFRTITSTYYRGTHGVIVVYDVTSAESFVNVK---RWLHEINQNCDD 112
           +V     DTAGQE + ++   Y R   G IVVY VT   SF   +   RWL    Q+   
Sbjct: 125 RVSWTFLDTAGQEEYSSMREHYTRSGDGFIVVYSVTDVTSFQEAEAVFRWLTRF-QDETS 301

Query: 113 VCRILVGNKNDDPERKVVETEDAYKFAGQMGIQLFETSAKENVNVEEMFNCITELVLR 170
           +  +L GNK D    + V  E+  K A ++G+  FETSAK   NV ++++ +   + R
Sbjct: 302 IHAVLCGNKTDLTSDRKVTPEEGRKMADRLGMLYFETSAKTGDNVSQVYHGLLRSIPR 475

 Score = 38.1 bits (87), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 17/48 (35%), Positives = 32/48 (66%)
 Frame = +2

Query: 9   FKLLIIGDSGVGKSSLLLRFADNTFSGSYITTIGVDFKIRTVEINGEK 56
           +K++++G  GVGKSSL +RF  +TF   Y  TI   ++ + ++++G+ 
Sbjct: 488 YKIVMLGSGGVGKSSLTIRFTQDTFLDVYDPTIEDSYR-KMIQVSGQP 628
>27191
          Length = 443

 Score = 65.9 bits (159), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 29/102 (28%), Positives = 57/102 (55%), Gaps = 1/102 (0%)
 Frame = +1

Query: 21  KSSLLLRFADNTFSGSYITTIGVDFKIRTVEINGEKVKLQIWDTAGQERFRTITSTYYRG 80
           K+ L+  F ++ F+  Y  T+GVD+  +   +NG  +++ +WD +G   +  + +  Y G
Sbjct: 1   KTCLIKHFCESKFNQGYQPTVGVDYGFKIQTVNGVDMRVHMWDLSGSNEYLDVRNELYTG 180

Query: 81  THGVIVVYDVTSAESFVNVKRWLHEINQ-NCDDVCRILVGNK 121
           +  + +V+DV++  SF  +  WL EIN+        ++VGN+
Sbjct: 181 SDAIFIVFDVSNTPSFEALDSWLREINRFATGSPLNVIVGNR 306
>34359
          Length = 1042

 Score = 65.9 bits (159), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 39/126 (30%), Positives = 72/126 (57%), Gaps = 5/126 (3%)
 Frame = +3

Query: 9   FKLLIIGDSGVGKSSLLLRFADNTFSGS---YITTIGVDFKIRTVEINGEK--VKLQIWD 63
           FKL+++G      ++++ R      +GS   Y+ T+GV+  +  ++ N  +  ++  +WD
Sbjct: 54  FKLVLVGGRWEWANNIVKRHV----TGS*KKYVATLGVE--VHPLQFNTSRGLLRFNVWD 215

Query: 64  TAGQERFRTITSTYYRGTHGVIVVYDVTSAESFVNVKRWLHEINQNCDDVCRILVGNKND 123
           TAGQE+F  +   YY      I+++DVTS  ++ NV  W  ++ + C+++  +L GNK D
Sbjct: 216 TAGQEKFGGLRDGYYIQGTCAIIMFDVTSRVTYKNVPNWHRDLVRVCENIPIVLCGNKVD 395

Query: 124 DPERKV 129
             +RKV
Sbjct: 396 IKDRKV 413
>00858
          Length = 1658

 Score = 64.7 bits (156), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 54/155 (34%), Positives = 79/155 (50%), Gaps = 2/155 (1%)
 Frame = -2

Query: 9    FKLLIIGDSGVGKSSLLLRFADNTFSGSYITTIGVDFKIRTVEINGEKVKLQIWDTAGQE 68
            +KL+++G  GVGKS+L ++   N F   Y  T   D   + V I+GE   L I DTAGQE
Sbjct: 1588 YKLVVVGAGGVGKSALTIQLXQNHFVEEYDPTXE-DSXRKQVVIDGETCLLDILDTAGQE 1412

Query: 69   RFRTITSTYYRGTHGVIVVYDVTSAESFVNVKRWLHEIN--QNCDDVCRILVGNKNDDPE 126
                +     R   G + V+ V + +SF ++ ++  +I   ++ D+V  +LVGNK D P 
Sbjct: 1411 EXSAMRDQCMRTGEGFLCVFAVXNLKSFEDINQYREQIKRVKDADEVPMVLVGNKVDLPI 1232

Query: 127  RKVVETEDAYKFAGQMGIQLFETSAKENVNVEEMF 161
            R  VE       A    I   ETSAK    V++ F
Sbjct: 1231 RN-VEQRQGKHMAELYHIPYVETSAKTRQGVDDAF 1130
>09204
          Length = 1051

 Score = 62.8 bits (151), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 31/102 (30%), Positives = 54/102 (52%), Gaps = 4/102 (3%)
 Frame = -3

Query: 69   RFRTITSTYYRGTHGVIVVYDVTSAESFVNVKRWLHEINQNCDDVCRILVGNK----NDD 124
            R+  ++  YYRG    I+ +D+T   SF  ++ W+ E+ Q+ ++    + G K    +DD
Sbjct: 1049 RYEAMSRIYYRGAKAAILCFDLTDKSSFDRIRFWIGELRQHEEECKLYICGTKFDLVHDD 870

Query: 125  PERKVVETEDAYKFAGQMGIQLFETSAKENVNVEEMFNCITE 166
            PER+ V    A   A     +++ETS+    N+E++F  I E
Sbjct: 869  PERRAVPRSVAKALADDCMAEIYETSSMTGDNIEKLFTKIAE 744
>12339
          Length = 578

 Score = 62.4 bits (150), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 38/108 (35%), Positives = 59/108 (54%), Gaps = 5/108 (4%)
 Frame = -2

Query: 67  QERFRTITSTYYRGTHGVIVVYDVTSAESFVNVKRWLHE-INQ----NCDDVCRILVGNK 121
           QERF+++   +YRG    I+VYDVT  ++F ++  W  E +NQ    + +    +++GNK
Sbjct: 577 QERFQSLGVAFYRGADCCILVYDVTEXKTFDSLDSWQREFLNQASPRDPEHFPFVVIGNK 398

Query: 122 NDDPERKVVETEDAYKFAGQMGIQLFETSAKENVNVEEMFNCITELVL 169
            D   R V         + + GI  FETSAKE +NVE+ F  + +  L
Sbjct: 397 IDLDNRVVTAKRGQGWCSTKGGIPYFETSAKEAINVEQAFQTVAKNAL 254
>13745
          Length = 1045

 Score = 60.1 bits (144), Expect = 7e-10,   Method: Compositional matrix adjust.
 Identities = 36/108 (33%), Positives = 55/108 (50%), Gaps = 5/108 (4%)
 Frame = +2

Query: 67  QERFRTITSTYYRGTHGVIVVYDVTSAESFVNVKRWLHEI-----NQNCDDVCRILVGNK 121
           QERF+++   +YRG    ++VYDVT+  SF N+  W  E       ++ +    +++GNK
Sbjct: 2   QERFQSLGVAFYRGADCCVLVYDVTAPNSFKNLDSWRDEFLIQASPRDPEHFPFVVLGNK 181

Query: 122 NDDPERKVVETEDAYKFAGQMGIQLFETSAKENVNVEEMFNCITELVL 169
            D   R+V           +  I  +ETSAKE +NVE  F  I +  L
Sbjct: 182 VDLDNRQVSTRRAQQWCQSKNDIPYYETSAKEGINVEMAFQTIAKNAL 325
>01095
          Length = 1745

 Score = 55.1 bits (131), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 29/82 (35%), Positives = 48/82 (58%), Gaps = 1/82 (1%)
 Frame = -1

Query: 86   VVYDVTSAESFVNVKRWLHEIN-QNCDDVCRILVGNKNDDPERKVVETEDAYKFAGQMGI 144
            VVYD+T+ ++F   K W+ E+  Q   ++   L GNK D   +++VE E+A  +A +  +
Sbjct: 1745 VVYDITNQDTFGRAKTWVKELQRQASPNIVIALAGNKADLANKRMVEFEEAQAYAEENSL 1566

Query: 145  QLFETSAKENVNVEEMFNCITE 166
               ETSAK  +NV ++F  I +
Sbjct: 1565 LFMETSAKTAMNVNDIFLAIAK 1500
>29380
          Length = 853

 Score = 54.3 bits (129), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 32/90 (35%), Positives = 48/90 (53%), Gaps = 2/90 (2%)
 Frame = -2

Query: 83  GVIVVYDVTSAESFVNVKRWLHEI-NQNCDDVCRILVGNKND-DPERKVVETEDAYKFAG 140
             I+VYDV  A++F     W+ E+  QN + V  IL GNK D   + + V  EDA  FA 
Sbjct: 846 AAIIVYDVNIADTFSRALAWVKELRQQNTESVLIILAGNKVDLATQHRAVSFEDAQSFAR 667

Query: 141 QMGIQLFETSAKENVNVEEMFNCITELVLR 170
           + G+   E SAK  + V E+F  +   +++
Sbjct: 666 ENGLLFAEVSAKTGMAVNEIFMTLANQLIQ 577
>34597
          Length = 773

 Score = 53.9 bits (128), Expect = 4e-08,   Method: Compositional matrix adjust.
 Identities = 28/76 (36%), Positives = 47/76 (61%), Gaps = 1/76 (1%)
 Frame = -2

Query: 95  SFVNVKRWLHEINQNC-DDVCRILVGNKNDDPERKVVETEDAYKFAGQMGIQLFETSAKE 153
           SF N+ +WL  I+++  +DV ++++GNK D  +++VV  E     A +  I+  ETSAK 
Sbjct: 709 SFENIVKWLRNIDEHANEDVEKMILGNKCDMTDKRVVSKERGEAIAREHSIRFMETSAKS 530

Query: 154 NVNVEEMFNCITELVL 169
           N+N+E  F  + E +L
Sbjct: 529 NINIERAFCELAEAIL 482
>00552
          Length = 455

 Score = 50.8 bits (120), Expect = 4e-07,   Method: Compositional matrix adjust.
 Identities = 24/53 (45%), Positives = 34/53 (64%)
 Frame = -1

Query: 8   LFKLLIIGDSGVGKSSLLLRFADNTFSGSYITTIGVDFKIRTVEINGEKVKLQ 60
           L K++++GD GVGKSSL+ RF  N F      TIGV+F  + V ++GE   +Q
Sbjct: 446 LLKVVLLGDGGVGKSSLMNRFVSNKFDAQSFHTIGVEFLTKDVVVDGETFTMQ 288

 Score = 45.4 bits (106), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 17/46 (36%), Positives = 30/46 (65%)
 Frame = -3

Query: 61  IWDTAGQERFRTITSTYYRGTHGVIVVYDVTSAESFVNVKRWLHEI 106
           IWDTAGQER++++ + +YRGT   ++ + V + +S  ++  W  E 
Sbjct: 147 IWDTAGQERYKSLRTPFYRGTDCCLLTFSVDNLKSLQSLSDWYDEF 10
>08153
          Length = 1703

 Score = 50.4 bits (119), Expect = 5e-07,   Method: Compositional matrix adjust.
 Identities = 33/119 (27%), Positives = 56/119 (47%), Gaps = 3/119 (2%)
 Frame = +1

Query: 10  KLLIIGDSGVGKSSLLLRFADNTFSGSYITTIG-VDFKIRTVEINGEKVKLQIWDTAGQE 68
           ++L++G    GK+++L +       G  +TTI  + F + TVE   + +   +WD  GQ+
Sbjct: 88  RILMVGLDAAGKTTILYKLK----LGEIVTTIPTIGFNVETVEY--KNISFTVWDVGGQD 249

Query: 69  RFRTITSTYYRGTHGVIVVYDVTSAESFVNVKRWLHEINQNCD--DVCRILVGNKNDDP 125
           + R +   Y++ T G+I V D    E     K  L  +    D  D   ++  NK D P
Sbjct: 250 KIRPLWRHYFQNTQGLIFVVDSNDRERINEAKEELARMLNEDDLRDAIILVFANKQDLP 426
>10708
          Length = 2775

 Score = 38.5 bits (88), Expect(2) = 7e-07,   Method: Compositional matrix adjust.
 Identities = 14/46 (30%), Positives = 27/46 (58%)
 Frame = -2

Query: 55   EKVKLQIWDTAGQERFRTITSTYYRGTHGVIVVYDVTSAESFVNVK 100
            ++V+L +WDTAGQE +  +    Y  T  +++ + + S +S  N+ 
Sbjct: 2729 QQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIP 2592

 Score = 30.8 bits (68), Expect(2) = 7e-07,   Method: Compositional matrix adjust.
 Identities = 26/94 (27%), Positives = 36/94 (38%), Gaps = 21/94 (22%)
 Frame = -3

Query: 98   NVKRWLHEINQNCDDVCRILVGNKND---------------------DPERKVVETEDAY 136
            ++K+W  E+   C +V  ILVGNK D                     D  R + E  +AY
Sbjct: 2596 SLKKWTPEVRHFCPNVPIILVGNKKDLRNDENTKRELMKMKQEPVRLDEGRAMSEKINAY 2417

Query: 137  KFAGQMGIQLFETSAKENVNVEEMFNCITELVLR 170
             +         E SAK    V E+F   T   L+
Sbjct: 2416 SY--------LECSAKTKEGVREVFETATRAALQ 2339
>09827
          Length = 1201

 Score = 49.7 bits (117), Expect = 8e-07,   Method: Compositional matrix adjust.
 Identities = 33/123 (26%), Positives = 57/123 (46%), Gaps = 5/123 (4%)
 Frame = -3

Query: 9    FKLLIIGDSGVGKSSLLLRFADNTFSGSYITTIG-VDFKIRTVEINGEKVKLQIWDTAGQ 67
             ++L++G    GK+++L +       G  +TTI  + F + TVE   + +   +WD  GQ
Sbjct: 1112 MRILMVGLDAAGKTTILYKLK----LGEIVTTIPTIGFNVETVEY--KNISFTVWDVGGQ 951

Query: 68   ERFRTITSTYYRGTHGVIVVYDVTSAESFVNVK----RWLHEINQNCDDVCRILVGNKND 123
            ++ R +   Y++ T G+I V D    E     +    R L+E      D   ++  NK D
Sbjct: 950  DKIRPLWRHYFQNTQGLIFVVDSNDKERVQEAREELTRMLNE--DELRDAVLLVFANKQD 777

Query: 124  DPE 126
             P 
Sbjct: 776  LPH 768
>33605
          Length = 888

 Score = 47.8 bits (112), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 30/94 (31%), Positives = 48/94 (51%), Gaps = 2/94 (2%)
 Frame = +1

Query: 10  KLLIIGDSGVGKSSLLLRFADNTFSGSYITTIG--VDFKIRTVEINGEKVKLQIWDTAGQ 67
           +LL++G    GK+++L +F     +G  I TI   + F I+T+E  G   KL +WD  GQ
Sbjct: 502 RLLMLGLDNAGKTTILKKF-----NGEDIDTISPTLGFNIKTLEHRG--FKLNVWDVGGQ 660

Query: 68  ERFRTITSTYYRGTHGVIVVYDVTSAESFVNVKR 101
           +  R+    Y+  T G++ V D        + KR
Sbjct: 661 QSLRSYWRNYFESTDGLVWVVDSADRMRIADCKR 762
>31291
          Length = 446

 Score = 47.4 bits (111), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 25/66 (37%), Positives = 35/66 (53%), Gaps = 1/66 (1%)
 Frame = -1

Query: 59  LQIWDTAGQERFRTITSTYYRGTHGVIVVYDVTSAESFVNVK-RWLHEINQNCDDVCRIL 117
           LQ+WDTAGQE +  +    Y  T   ++ + + S  S  NVK +W  EI  +   V  +L
Sbjct: 446 LQLWDTAGQEDYDRLRPLAYPNTDVFMLXFSLMSEASMKNVKVKWYPEIRHHDPHVPIVL 267

Query: 118 VGNKND 123
           VG K D
Sbjct: 266 VGTKLD 249
>10862
          Length = 2896

 Score = 44.3 bits (103), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 21/74 (28%), Positives = 37/74 (50%), Gaps = 2/74 (2%)
 Frame = -3

Query: 55   EKVKLQIWDTAGQERFRTITSTYYRGTHGVIVVYDVTSAESFVNVKRWLHEI--NQNCDD 112
            ++ +  +WD  GQ++ R +   YY GT G+I V D    +     ++ LH I  ++   D
Sbjct: 2492 QECQFNVWDVGGQDKIRPLWRHYYTGTQGLIFVVDCADRDRIDEARQELHRIINDREMRD 2313

Query: 113  VCRILVGNKNDDPE 126
               ++  NK D P+
Sbjct: 2312 AIILIFANKQDLPD 2271
>14775
          Length = 380

 Score = 42.7 bits (99), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 40/154 (25%), Positives = 61/154 (39%), Gaps = 4/154 (2%)
 Frame = -2

Query: 21  KSSLLLRFADNTFSGSYITTIGV---DF-KIRTVEINGEKVKLQIWDTAGQERFRTITST 76
           K+ LL R+    F    + TI V   +F + RT  +N   V+  +WDT G E +R++  +
Sbjct: 379 KTCLLRRYQKGFFMDRTMPTIAVLCSEFNESRTDPLN---VRYTLWDTGGAETYRSLWVS 209

Query: 77  YYRGTHGVIVVYDVTSAESFVNVKRWLHEINQNCDDVCRILVGNKNDDPERKVVETEDAY 136
           ++RG    ++VYDVT                                         E   
Sbjct: 208 HFRGAQVALLVYDVTC----------------------------------------ERGQ 149

Query: 137 KFAGQMGIQLFETSAKENVNVEEMFNCITELVLR 170
            FA Q G   FETS+    NV+ +F  I  ++ R
Sbjct: 148 AFATQCGYTFFETSSVTGKNVDAVFWEIAFILAR 47
>25796
          Length = 422

 Score = 39.3 bits (90), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 17/28 (60%), Positives = 20/28 (71%)
 Frame = -1

Query: 1  MARDYDHLFKLLIIGDSGVGKSSLLLRF 28
          M+  YD+LFK LIIG +G GKS LL  F
Sbjct: 89 MSETYDYLFKFLIIGSAGSGKSCLLHHF 6
>31928
          Length = 429

 Score = 34.7 bits (78), Expect = 0.027,   Method: Compositional matrix adjust.
 Identities = 25/76 (32%), Positives = 40/76 (52%), Gaps = 5/76 (6%)
 Frame = +2

Query: 54  GEKVKLQIWDTAGQERFRT---ITSTYYRGTHGVIVVYDVTSAESFVNVKRWLHEINQNC 110
           G K K++I+DT       T   +   Y     G ++VYD TS ESF  + +   +I+++ 
Sbjct: 95  GVKEKVRIFDTGAAALETTEGDLPKHYLNFPDGFVLVYDTTSWESFRRLDKLKKDIDKHR 274

Query: 111 D--DVCRILVGNKNDD 124
           D  +V  I++GNK  D
Sbjct: 275 DKREVHMIVIGNKE*D 322
>09700
          Length = 1855

 Score = 32.3 bits (72), Expect = 0.12,   Method: Compositional matrix adjust.
 Identities = 17/38 (44%), Positives = 22/38 (57%), Gaps = 1/38 (2%)
 Frame = -1

Query: 128  KVVETEDAYKFAGQMGIQLFETSAKENVNVEEMFN-CI 164
            K V  +DA K A Q+G    E SA    N++EMF+ CI
Sbjct: 1735 KPVSEDDASKLAHQLGASYVECSALTQKNLKEMFDSCI 1622
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|82886148|ref|XP_130308.4| PREDICTED: low density
lipoprotein receptor-related protein 2 isoform 1 [Mus musculus]
         (4660 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

05956                                                                 142   4e-33
38381                                                                  91   4e-20
34993                                                                  74   1e-12
30369                                                                  54   4e-12
20820                                                                  67   2e-10
14418                                                                  66   3e-10
36074                                                                  49   3e-10
28816                                                                  62   4e-09
35170                                                                  62   5e-09
29665                                                                  60   2e-08
25748                                                                  60   2e-08
11992                                                                  59   4e-08
34726                                                                  55   8e-07
14371                                                                  54   1e-06
14599                                                                  54   2e-06
11667                                                                  51   1e-05
27664                                                                  48   8e-05
25877                                                                  45   6e-04
30893                                                                  44   0.001
03773                                                                  44   0.002
18708                                                                  43   0.003
26964                                                                  42   0.007
14158                                                                  42   0.008
22430                                                                  41   0.011
18588                                                                  40   0.019
19898                                                                  40   0.029
03572                                                                  35   0.55 
03995                                                                  33   3.9  
13514                                                                  32   4.1  
22230                                                                  32   7.0  
21089                                                                  32   7.9  
>05956
          Length = 1259

 Score =  142 bits (357), Expect = 4e-33,   Method: Compositional matrix adjust.
 Identities = 102/310 (32%), Positives = 161/310 (51%), Gaps = 9/310 (2%)
 Frame = +1

Query: 2379 DGKNCATS-RE-DFLIYSLNNSLRSLHFDPQDHNLPFQAISVEG-MAIALDYDRRNNRIF 2435
            DG+ C T+ RE + L+Y+  + + S+   PQ  +   Q     G +AIA+D D    +++
Sbjct: 40   DGRTCTTAVREGERLLYARGSKVFSVSTSPQPGDYGQQIDFTPGQLAIAVDMDCAQGQVY 219

Query: 2436 FTQKLNPIRGQISYVNLYSGASSPTILLSNIGVTDGIAFDWINRRIYYSDFSNQTINSMA 2495
            +T   +   G I   NL  G +    +L+ +G  +GIA D ++R +YY+D     + +  
Sbjct: 220  WT---DAAAGVIRKANLTGGPTQ--TVLTGLGSPEGIAVDSVSRILYYTDSKLDLVGAAL 384

Query: 2496 EDGSNRAVI--ARVSKPRAIVLDPCRGYMYWTDWGTNA-KIERATLGGNFRVPIVNTSLV 2552
             DGS R  +    +  PRAIVLD  RG +YWTDW  N  +IE A + G+ R  +++  L 
Sbjct: 385  LDGSYRKTLFNTDMVNPRAIVLDNNRGKIYWTDWNRNKPQIEMANMDGSERRVLLDVDLR 564

Query: 2553 WPNGLTLDLETDLLYWADASLQKIERSTLTGSNREVVISTAFHSFGLTVYGQYIYWTDFY 2612
             PNGL  DL +  L WADA  +++E     G  R VV +   + F +T+    +YWTD+ 
Sbjct: 565  LPNGLAFDLYSQQLCWADAGTKRLECIRSDGLGRRVVSTAPSYPFSVTMLNNMLYWTDWE 744

Query: 2613 TKKIYRANKYDGSDLIAMTTRLP--TQPSGISTVVKTQQQQCSNPCDQFNGGCSHICAPG 2670
             K I   +   G  + +++  L    +  GI+  V+ +  + SN C   NGGC+ +C P 
Sbjct: 745  RKDIGGVSHTGGDQVTSVSPALGGNGRMYGIAP-VRDRCPRGSNSCAFNNGGCAFLCFPT 921

Query: 2671 PNGAE-CQCP 2679
            P+G   C CP
Sbjct: 922  PSGGRTCACP 951

 Score =  140 bits (354), Expect = 9e-33,   Method: Compositional matrix adjust.
 Identities = 104/340 (30%), Positives = 159/340 (46%), Gaps = 16/340 (4%)
 Frame = +1

Query: 3174 GSYICKCAPGYIREPDGKSCRQNSNIEPYLVFSNRYYIRNLT-----------IDGTSYS 3222
            G Y+C C   Y    DG++C         L+++    + +++           ID T   
Sbjct: 1    GQYVCVCNYNY--RGDGRTCTTAVREGERLLYARGSKVFSVSTSPQPGDYGQQIDFTPGQ 174

Query: 3223 LILQGLGNVVALDFDRVEERLYWIDAEKQIIERMFLNKTNQETIISHRLRRAESLAVDWV 3282
            L        +A+D D  + ++YW DA   +I +  L     +T+++  L   E +AVD V
Sbjct: 175  L-------AIAVDMDCAQGQVYWTDAAAGVIRKANLTGGPTQTVLTG-LGSPEGIAVDSV 330

Query: 3283 SRKLYWLDAILDCLFVSDLEGRQRKMLAQHCVDANNTFCFENPRGIVLHPQRGYVYWADW 3342
            SR LY+ D+ LD +  + L+G  RK L    +         NPR IVL   RG +YW DW
Sbjct: 331  SRILYYTDSKLDLVGAALLDGSYRKTLFNTDM--------VNPRAIVLDNNRGKIYWTDW 486

Query: 3343 G-DHAYIARIGMDGTNKTVIISTKIEWPNAITIDYTNDLLYWADAHLGYIEFSDLEGHHR 3401
              +   I    MDG+ + V++   +  PN +  D  +  L WADA    +E    +G  R
Sbjct: 487  NRNKPQIEMANMDGSERRVLLDVDLRLPNGLAFDLYSQQLCWADAGTKRLECIRSDGLGR 666

Query: 3402 HTVYDGTLP-HPFALTIFEDTVFWTDWNTRTVEKGNKYDGSGRVVLVN-TTHKPFDIHVL 3459
              V   T P +PF++T+  + ++WTDW  + +  G  + G  +V  V+        ++ +
Sbjct: 667  RVV--STAPSYPFSVTMLNNMLYWTDWERKDI-GGVSHTGGDQVTSVSPALGGNGRMYGI 837

Query: 3460 HPYRQ--PIMSNPCATNNGGCSHLCLIKAGGRGFTCECPD 3497
             P R   P  SN CA NNGGC+ LC     G G TC CPD
Sbjct: 838  APVRDRCPRGSNSCAFNNGGCAFLCFPTPSG-GRTCACPD 954

 Score =  134 bits (338), Expect = 6e-31,   Method: Compositional matrix adjust.
 Identities = 95/330 (28%), Positives = 156/330 (47%), Gaps = 8/330 (2%)
 Frame = +1

Query: 1410 GSFRCACDPEYTLESDGRTCKVTASENLLLVVASRDKIIMDNITAHTHNIYSLVQDVS-- 1467
            G + C C+  Y    DGRTC     E   L+ A   K+   + +    + Y    D +  
Sbjct: 1    GQYVCVCN--YNYRGDGRTCTTAVREGERLLYARGSKVFSVSTSPQPGD-YGQQIDFTPG 171

Query: 1468 -FVVALDFDSVTGRVFWSDLLEGKTWSAFQNGTDKRVVHDSGLSLTEMIAVDWIGRNIYW 1526
               +A+D D   G+V+W+D   G    A   G   + V  +GL   E IAVD + R +Y+
Sbjct: 172  QLAIAVDMDCAQGQVYWTDAAAGVIRKANLTGGPTQTVL-TGLGSPEGIAVDSVSRILYY 348

Query: 1527 TDYTLETIEVSKIDGSHRTVLISKNVTKPRGLALDPRMGDNVMFWSDWGHH-PRIERASM 1585
            TD  L+ +  + +DGS+R  L + ++  PR + LD   G   ++W+DW  + P+IE A+M
Sbjct: 349  TDSKLDLVGAALLDGSYRKTLFNTDMVNPRAIVLDNNRGK--IYWTDWNRNKPQIEMANM 522

Query: 1586 DGTMRTVIVQEKIYWPCGLSIDYPNRLIYFMDAYLDYIEFCDYDGQNRRQVIASDLVLHH 1645
            DG+ R V++   +  P GL+ D  ++ + + DA    +E    DG  RR V  +     +
Sbjct: 523  DGSERRVLLDVDLRLPNGLAFDLYSQQLCWADAGTKRLECIRSDGLGRRVVSTAP---SY 693

Query: 1646 PHALTLFEDSVFWTDRGTHQVMQANKWHGRNQSVVMYSVPQPLGIIAIHPSRQ--PSSPN 1703
            P ++T+  + ++WTD     +   +   G   + V  ++     +  I P R   P   N
Sbjct: 694  PFSVTMLNNMLYWTDWERKDIGGVSHTGGDQVTSVSPALGGNGRMYGIAPVRDRCPRGSN 873

Query: 1704 PCA--SATCSHLCLLSAQEPRHYSCACPSG 1731
             CA  +  C+ LC  +    R  +CACP G
Sbjct: 874  SCAFNNGGCAFLCFPTPSGGR--TCACPDG 957

 Score =  132 bits (332), Expect = 3e-30,   Method: Compositional matrix adjust.
 Identities = 72/255 (28%), Positives = 134/255 (52%), Gaps = 5/255 (1%)
 Frame = +1

Query: 424 IVMGVDFHYQKHRVFWTDPMQAKVFSTDINGLNTQEILNVSIDAPENLAVDWINNKLYLV 483
           + + VD    + +V+WTD     +   ++ G  TQ +L   + +PE +AVD ++  LY  
Sbjct: 175 LAIAVDMDCAQGQVYWTDAAAGVIRKANLTGGPTQTVL-TGLGSPEGIAVDSVSRILYYT 351

Query: 484 ETRVNRIDVVNLEGNQRVTLITENLGHPRGIALDPTVGYLFFSDWGSLSGQPKVERAFMD 543
           +++++ +    L+G+ R TL   ++ +PR I LD   G ++++DW     +P++E A MD
Sbjct: 352 DSKLDLVGAALLDGSYRKTLFNTDMVNPRAIVLDNNRGKIYWTDWN--RNKPQIEMANMD 525

Query: 544 GSNRKDLVTTKLGWPAGITLDLVSKRVYWVDSRYDYIETVTYDGIQRKTVARGGSLVPHP 603
           GS R+ L+   L  P G+  DL S+++ W D+    +E +  DG+ R+ V+   S   +P
Sbjct: 526 GSERRVLLDVDLRLPNGLAFDLYSQQLCWADAGTKRLECIRSDGLGRRVVSTAPS---YP 696

Query: 604 FGISLFEEHVFFTDWTKMAV-----MKANKFTDTNPQVYHQSSLTPFGVTVYHALRQPNA 658
           F +++    +++TDW +  +        ++ T  +P +     +  +G+      R P  
Sbjct: 697 FSVTMLNNMLYWTDWERKDIGGVSHTGGDQVTSVSPALGGNGRM--YGIAPVRD-RCPRG 867

Query: 659 TNPCGNNNGGCAQIC 673
           +N C  NNGGCA +C
Sbjct: 868 SNSCAFNNGGCAFLC 912

 Score =  121 bits (304), Expect = 5e-27,   Method: Compositional matrix adjust.
 Identities = 84/255 (32%), Positives = 130/255 (50%), Gaps = 9/255 (3%)
 Frame = +1

Query: 4115 GAIKRAYLPDFESGSNNPVREVDLGLKYLMQPDGLAVDWVGRHIYWSDAKSQRIEVATLD 4174
            G I++A L      +  P + V  GL     P+G+AVD V R +Y++D+K   +  A LD
Sbjct: 238  GVIRKANL------TGGPTQTVLTGLG---SPEGIAVDSVSRILYYTDSKLDLVGAALLD 390

Query: 4175 GRYRKWLITTQLDQPAAIAVNPKLGLMFWTDQGK-QPKIESAWMNGEHRSVLASANLGWP 4233
            G YRK L  T +  P AI ++   G ++WTD  + +P+IE A M+G  R VL   +L  P
Sbjct: 391  GSYRKTLFNTDMVNPRAIVLDNNRGKIYWTDWNRNKPQIEMANMDGSERRVLLDVDLRLP 570

Query: 4234 NGLSIDYLNGDRIYWSDSKEDVIESIKYDGTDRRLIINDAMKPFSLDIFEDQLYWVAKEK 4293
            NGL+ D L   ++ W+D+    +E I+ DG  RR++      PFS+ +  + LYW   E+
Sbjct: 571  NGLAFD-LYSQQLCWADAGTKRLECIRSDGLGRRVVSTAPSYPFSVTMLNNMLYWTDWER 747

Query: 4294 GEVWRQNKFGKGNKEKLLVVNPWLTQVRIFHQLRYNQSV----SNPCK---QVCSHLCLL 4346
             ++   +  G    +++  V+P L      + +   +      SN C      C+ LC  
Sbjct: 748  KDIGGVSHTG---GDQVTSVSPALGGNGRMYGIAPVRDRCPRGSNSCAFNNGGCAFLCFP 918

Query: 4347 RP-GGYSCACPQGSD 4360
             P GG +CACP G D
Sbjct: 919  TPSGGRTCACPDGVD 963

 Score =  112 bits (281), Expect = 3e-24,   Method: Compositional matrix adjust.
 Identities = 86/328 (26%), Positives = 149/328 (45%), Gaps = 10/328 (3%)
 Frame = +1

Query: 686  YRCKCEFGFELDADE-HHCVAVKNFLLFSSQTAVRGIPFTLSTQE---DVMVPVTGSPS- 740
            Y C C + +  D       V     LL++  + V    F++ST     D    +  +P  
Sbjct: 7    YVCVCNYNYRGDGRTCTTAVREGERLLYARGSKV----FSVSTSPQPGDYGQQIDFTPGQ 174

Query: 741  FFVGIDFDAQHSTIFYSDLSKNIIYQQKIDGTGKEVITANRLQNVECLSFDWISRNLYWT 800
              + +D D     ++++D +  +I +  + G   + +    L + E ++ D +SR LY+T
Sbjct: 175  LAIAVDMDCAQGQVYWTDAAAGVIRKANLTGGPTQTVLTG-LGSPEGIAVDSVSRILYYT 351

Query: 801  DGGSKSVTVMKLADKSRRQII-SNLNNPRSIVVHPAAGYMFLSDWFR-PAKIMRAWSDGS 858
            D     V    L    R+ +  +++ NPR+IV+    G ++ +DW R   +I  A  DGS
Sbjct: 352  DSKLDLVGAALLDGSYRKTLFNTDMVNPRAIVLDNNRGKIYWTDWNRNKPQIEMANMDGS 531

Query: 859  HLMPIVNTSLGWPNGLAIDWSTSRLYWVDAFFDKIEHSNLDGLDRKRLGHVDQMTHPFGL 918
                +++  L  PNGLA D  + +L W DA   ++E    DGL R+ +      ++PF +
Sbjct: 532  ERRVLLDVDLRLPNGLAFDLYSQQLCWADAGTKRLECIRSDGLGRRVVSTAP--SYPFSV 705

Query: 919  TVFKDNVFLTDWRLGAIIRVRKSDGGDMTVVRRGISS---IMHVKAYDADLQTGTNYCSQ 975
            T+  + ++ TDW    I  V  + G  +T V   +     +  +         G+N C+ 
Sbjct: 706  TMLNNMLYWTDWERKDIGGVSHTGGDQVTSVSPALGGNGRMYGIAPVRDRCPRGSNSCA- 882

Query: 976  TTHPNGDCSHFCFPVPNFQRVCGCPYGM 1003
                NG C+  CFP P+  R C CP G+
Sbjct: 883  --FNNGGCAFLCFPTPSGGRTCACPDGV 960

 Score =  100 bits (250), Expect = 1e-20,   Method: Compositional matrix adjust.
 Identities = 90/343 (26%), Positives = 152/343 (44%), Gaps = 12/343 (3%)
 Frame = +1

Query: 2040 GMFSCACASGFKLSPDGRSCSPYNSFIVVSMLPAVRG---FSLELS----DHSEAMVPVA 2092
            G + C C   ++   DGR+C+   +      L   RG   FS+  S    D+ + +    
Sbjct: 1    GQYVCVCNYNYR--GDGRTCT--TAVREGERLLYARGSKVFSVSTSPQPGDYGQQIDFTP 168

Query: 2093 GQGRNVLHADVDVANGFIYWCDFSSSVRSSNGIRRIKPNGSNFTNIVTYGIGANGIRGVA 2152
            GQ    +  D+D A G +YW D ++ V     IR+    G     ++T G+G+    G+A
Sbjct: 169  GQ--LAIAVDMDCAQGQVYWTDAAAGV-----IRKANLTGGPTQTVLT-GLGSP--EGIA 318

Query: 2153 VDWVAGNLYFTNAFVYETLIEVIRINTTYRRVLLKVSVDMPRHIVVDPKHRYLFWADYGQ 2212
            VD V+  LY+T++ +   L+    ++ +YR+ L    +  PR IV+D     ++W D+ +
Sbjct: 319  VDSVSRILYYTDSKL--DLVGAALLDGSYRKTLFNTDMVNPRAIVLDNNRGKIYWTDWNR 492

Query: 2213 -KPKIERSFLDCTNRTVLVSEGIVTPRGLAVDHDTGYIYWVDDSLDIIARIHRDGGESQV 2271
             KP+IE + +D + R VL+   +  P GLA D  +  + W D     +  I  DG   +V
Sbjct: 493  NKPQIEMANMDGSERRVLLDVDLRLPNGLAFDLYSQQLCWADAGTKRLECIRSDGLGRRV 672

Query: 2272 VRYGSRYPTPYGITVFGESIIWVDRNLRKVFQASKQPGNTDPPTVIRDSINLLRDVTIFD 2331
            V     Y  P+ +T+    + W D   + +   S   G         D +  +      +
Sbjct: 673  VSTAPSY--PFSVTMLNNMLYWTDWERKDIGGVSHTGG---------DQVTSVSPALGGN 819

Query: 2332 EHVQPLSPAE----LNNNPCLQSNGGCSHFCFALPELPTPKCG 2370
              +  ++P        +N C  +NGGC+  CF     PTP  G
Sbjct: 820  GRMYGIAPVRDRCPRGSNSCAFNNGGCAFLCF-----PTPSGG 933

 Score = 94.0 bits (232), Expect = 1e-18,   Method: Compositional matrix adjust.
 Identities = 85/337 (25%), Positives = 135/337 (40%), Gaps = 9/337 (2%)
 Frame = +1

Query: 1723 HYSCACPSGWNLSDDSVNCVRG--DQPFLISVRENVIFGISLDPEVKSNDAMVPISGIQH 1780
             Y C C   +N   D   C     +   L+  R + +F +S  P+       +  +  Q 
Sbjct: 4    QYVCVC--NYNYRGDGRTCTTAVREGERLLYARGSKVFSVSTSPQPGDYGQQIDFTPGQL 177

Query: 1781 GYDVEFDDSEQFIYWVENPGEIHRVK--TDGSNRTAFAPXXXXXXXXXXXXDWVSRNIYY 1838
               V+ D ++  +YW +    + R    T G  +T                D VSR +YY
Sbjct: 178  AIAVDMDCAQGQVYWTDAAAGVIRKANLTGGPTQTVLT---GLGSPEGIAVDSVSRILYY 348

Query: 1839 TTPASRSIEVLTLRGDTRYGKTLITNDGTPLGVGFPVGIAVDPARGKLYWSDHGTDSGVP 1898
            T      +    L  D  Y KTL   D     +  P  I +D  RGK+YW+D   +    
Sbjct: 349  TDSKLDLVGAALL--DGSYRKTLFNTD-----MVNPRAIVLDNNRGKIYWTDWNRNK--- 498

Query: 1899 AKIASANMDGTSLKILFTGNMEHLEVVTLDIQEQKLYWAVTSRGVIERGNVDGTERMILV 1958
             +I  ANMDG+  ++L   ++     +  D+  Q+L WA      +E    DG  R ++ 
Sbjct: 499  PQIEMANMDGSERRVLLDVDLRLPNGLAFDLYSQQLCWADAGTKRLECIRSDGLGRRVVS 678

Query: 1959 HHLAHPWGLVVHGSFLYYSDEQYEVIERVDKSSGSNKVVFRDNIPYLRG-LRVYHHRNAA 2017
               ++P+ + +  + LY++D + + I  V  + G          P L G  R+Y      
Sbjct: 679  TAPSYPFSVTMLNNMLYWTDWERKDIGGVSHTGGDQVTSVS---PALGGNGRMYGIAPVR 849

Query: 2018 D----SSNGCSNNPNACQQICLPVPGGMFSCACASGF 2050
            D     SN C+ N   C  +C P P G  +CAC  G 
Sbjct: 850  DRCPRGSNSCAFNNGGCAFLCFPTPSGGRTCACPDGV 960
>38381
          Length = 658

 Score = 86.7 bits (213), Expect(2) = 4e-20,   Method: Compositional matrix adjust.
 Identities = 50/111 (45%), Positives = 69/111 (62%)
 Frame = +1

Query: 32  NFRCDNGYCIPASWRCDGTRDCLDDTDEIGCPPRSCGSGFFLCPAEGTCIPSSWVCDQDK 91
           +F C++G CI    RCDG  DC D +DE  CP   C    F C  +G CI + + C+   
Sbjct: 1   DFECEDGSCIDNRLRCDGVPDCSDRSDESNCP---CRDDQFSC-RDGLCIEAEFRCNGRV 168

Query: 92  DCSDGADEQQNCPGTTCSSQQLTCSNGQCVPIEYRCDHVSDCPDGSDERNC 142
           +C DG+DE++ CP  TCS  + TC +GQCV +  +C+ V+DC DGSDE+NC
Sbjct: 169 ECEDGSDEEE-CPRRTCSFAEFTCDDGQCVDLRDQCNQVTDCQDGSDEKNC 318

 Score = 32.7 bits (73), Expect(2) = 4e-20,   Method: Composition-based stats.
 Identities = 24/60 (40%), Positives = 35/60 (58%), Gaps = 2/60 (3%)
 Frame = +3

Query: 148 DQLTCAN-GACYNTSQKCDHKVDCRDSSDEANCTTLCSQKEFQCGS-GECILRAYVCDHD 205
           DQ TC + G C + +++CD + DC D SDE  C   C   EF+CG+    ++RA V D +
Sbjct: 330 DQFTCQDSGLCIDLARRCDRRRDCEDGSDEERCP--CLANEFRCGTVAAFLIRASVTDDE 503

 Score = 67.8 bits (164), Expect(3) = 7e-20,   Method: Compositional matrix adjust.
 Identities = 46/105 (43%), Positives = 57/105 (54%), Gaps = 1/105 (0%)
 Frame = +1

Query: 1122 CIPKEWVCDTDNDCSDGSDEKNCQASGTCHPTQFRCPDHRCISPLYVCDGDKDCVDGSDE 1181
            CI     CD   DCSD SDE NC     C   QF C D  CI   + C+G  +C DGSDE
Sbjct: 25   CIDNRLRCDGVPDCSDRSDESNC----PCRDDQFSCRDGLCIEAEFRCNGRVECEDGSDE 192

Query: 1182 AGC-VLNCTSSQFKCADGSSCINSRYRCDGVYDCKDNSDEAGCPT 1225
              C    C+ ++F C DG  C++ R +C+ V DC+D SDE  CP 
Sbjct: 193  EECPRRTCSFAEFTCDDGQ-CVDLRDQCNQVTDCQDGSDEKNCPA 324

 Score = 46.2 bits (108), Expect(3) = 7e-20,   Method: Compositional matrix adjust.
 Identities = 27/66 (40%), Positives = 35/66 (53%)
 Frame = +2

Query: 1241 DGTCIPNTWECDGHPDCIQGSDEHNGCVPKTCSPSHFLCDNGNCIYNSWVCDGDNDCRDM 1300
            DG CIP++ +CD   DC  GSDE        C  + F C++G C+     CD   +C D 
Sbjct: 458  DGRCIPDSRKCDRRRDCADGSDEEE--CEGVCGRNEFRCNDGTCVERRVKCDRFVNCPDG 631

Query: 1301 SDEKDC 1306
            SDE DC
Sbjct: 632  SDEFDC 649

 Score = 24.3 bits (51), Expect(3) = 7e-20,   Method: Composition-based stats.
 Identities = 8/15 (53%), Positives = 9/15 (60%)
 Frame = +3

Query: 1231 CHPDEFQCQGDGTCI 1245
            C  D+F CQ  G CI
Sbjct: 321  CRDDQFTCQDSGLCI 365

 Score = 68.9 bits (167), Expect(3) = 7e-20,   Method: Compositional matrix adjust.
 Identities = 47/101 (46%), Positives = 57/101 (56%)
 Frame = +1

Query: 3527 CIPIWWKCDGQKDCSDGSDESDLCPHRFCRLGQFQCRDGNCTSPQALCNARQDCADGSDE 3586
            CI    +CDG  DCSD SDES+ CP   CR  QF CRDG C   +  CN R +C DGSDE
Sbjct: 25   CIDNRLRCDGVPDCSDRSDESN-CP---CRDDQFSCRDGLCIEAEFRCNGRVECEDGSDE 192

Query: 3587 DRVLCEHHRCEANEWQCANKRCIPEYWQCDSVDDCLDNSDE 3627
            +   C    C   E+ C + +C+    QC+ V DC D SDE
Sbjct: 193  EE--CPRRTCSFAEFTCDDGQCVDLRDQCNQVTDCQDGSDE 309

 Score = 44.3 bits (103), Expect(3) = 7e-20,   Method: Compositional matrix adjust.
 Identities = 28/65 (43%), Positives = 34/65 (52%)
 Frame = +2

Query: 3693 RCIPQWAVCNGFDDCRDNSDEQGCESVPCHPSGDFRCGNHHCIPLRWKCDGIDDCGDNSD 3752
            RCIP    C+   DC D SDE+ CE V      +FRC +  C+  R KCD   +C D SD
Sbjct: 464  RCIPDSRKCDRRRDCADGSDEEECEGV--CGRNEFRCNDGTCVERRVKCDRFVNCPDGSD 637

Query: 3753 EESCV 3757
            E  C 
Sbjct: 638  EFDCA 652

 Score = 25.4 bits (54), Expect(3) = 7e-20,   Method: Composition-based stats.
 Identities = 19/52 (36%), Positives = 26/52 (50%), Gaps = 1/52 (1%)
 Frame = +3

Query: 3636 TCRPGQFKC-NNGRCIPQSWKCDVDNDCGDYSDEPIHECMTAAYNCDNHTEF 3686
            +CR  QF C ++G CI  + +CD   DC D SDE    C+   + C     F
Sbjct: 318  SCRDDQFTCQDSGLCIDLARRCDRRRDCEDGSDEERCPCLANEFRCGTVAAF 473

 Score = 75.5 bits (184), Expect(3) = 2e-19,   Method: Compositional matrix adjust.
 Identities = 45/113 (39%), Positives = 58/113 (51%)
 Frame = +1

Query: 3726 DFRCGNHHCIPLRWKCDGIDDCGDNSDEESCVPRECTESEFRCADQQCIPSRWVCDQEND 3785
            DF C +  CI  R +CDG+ DC D SDE +C    C + +F C D  CI + + C+   +
Sbjct: 1    DFECEDGSCIDNRLRCDGVPDCSDRSDESNCP---CRDDQFSCRDGLCIEAEFRCNGRVE 171

Query: 3786 CGDNSDERDCEMKTCHPEHFQCTSGHCVPKALACDGRADCLDASDESACPTRF 3838
            C D SDE +C  +TC    F C  G CV     C+   DC D SDE  CP   
Sbjct: 172  CEDGSDEEECPRRTCSFAEFTCDDGQCVDLRDQCNQVTDCQDGSDEKNCPAEM 330

 Score = 41.6 bits (96), Expect(3) = 2e-19,   Method: Compositional matrix adjust.
 Identities = 26/70 (37%), Positives = 36/70 (51%)
 Frame = +2

Query: 3895 NSRCIYGHQLCNGVDDCGDGSDEKEEHCRKPTHKPCTDTEYKCSNGNCVSQHYVCDNVDD 3954
            + RCI   + C+   DC DGSDE+E          C   E++C++G CV +   CD   +
Sbjct: 458  DGRCIPDSRKCDRRRDCADGSDEEE------CEGVCGRNEFRCNDGTCVERRVKCDRFVN 619

Query: 3955 CGDLSDETGC 3964
            C D SDE  C
Sbjct: 620  CPDGSDEFDC 649

 Score = 19.6 bits (39), Expect(3) = 2e-19,   Method: Composition-based stats.
 Identities = 20/51 (39%), Positives = 24/51 (47%), Gaps = 1/51 (1%)
 Frame = +3

Query: 3844 CPAAMFECKNH-VCIQSFWICDGENDCVDGSDEEIHLCFNVPCESPQRFRC 3893
            C    F C++  +CI     CD   DC DGSDEE       PC +   FRC
Sbjct: 321  CRDDQFTCQDSGLCIDLARRCDRRRDCEDGSDEE-----RCPCLA-NEFRC 455

 Score = 58.2 bits (139), Expect(2) = 4e-18,   Method: Compositional matrix adjust.
 Identities = 36/87 (41%), Positives = 48/87 (55%)
 Frame = +1

Query: 28  CGSGNFRCDNGYCIPASWRCDGTRDCLDDTDEIGCPPRSCGSGFFLCPAEGTCIPSSWVC 87
           C    F C +G CI A +RC+G  +C D +DE  CP R+C    F C  +G C+     C
Sbjct: 97  CRDDQFSCRDGLCIEAEFRCNGRVECEDGSDEEECPRRTCSFAEFTCD-DGQCVDLRDQC 273

Query: 88  DQDKDCSDGADEQQNCPGTTCSSQQLT 114
           +Q  DC DG+DE +NCP    SS+  T
Sbjct: 274 NQVTDCQDGSDE-KNCPAEMISSRVRT 351

 Score = 54.7 bits (130), Expect(2) = 4e-18,   Method: Compositional matrix adjust.
 Identities = 28/64 (43%), Positives = 37/64 (57%)
 Frame = +2

Query: 154 NGACYNTSQKCDHKVDCRDSSDEANCTTLCSQKEFQCGSGECILRAYVCDHDNDCEDNSD 213
           +G C   S+KCD + DC D SDE  C  +C + EF+C  G C+ R   CD   +C D SD
Sbjct: 458 DGRCIPDSRKCDRRRDCADGSDEEECEGVCGRNEFRCNDGTCVERRVKCDRFVNCPDGSD 637

Query: 214 EHNC 217
           E +C
Sbjct: 638 EFDC 649

 Score = 56.6 bits (135), Expect(3) = 4e-18,   Method: Compositional matrix adjust.
 Identities = 33/76 (43%), Positives = 46/76 (60%)
 Frame = +1

Query: 1025 CGSSSFPCNNGKCVPSIFRCDGVDDCHDNSDEHQCGALNNTCSSSAFTCVHGGQCIPGQW 1084
            C    F C +G C+ + FRC+G  +C D SDE +C     TCS + FTC   GQC+  + 
Sbjct: 97   CRDDQFSCRDGLCIEAEFRCNGRVECEDGSDEEEC--PRRTCSFAEFTC-DDGQCVDLRD 267

Query: 1085 RCDKQNDCLDGSDEQN 1100
            +C++  DC DGSDE+N
Sbjct: 268  QCNQVTDCQDGSDEKN 315

 Score = 50.4 bits (119), Expect(3) = 4e-18,   Method: Compositional matrix adjust.
 Identities = 29/65 (44%), Positives = 37/65 (56%)
 Frame = +2

Query: 1159 DHRCISPLYVCDGDKDCVDGSDEAGCVLNCTSSQFKCADGSSCINSRYRCDGVYDCKDNS 1218
            D RCI     CD  +DC DGSDE  C   C  ++F+C DG +C+  R +CD   +C D S
Sbjct: 458  DGRCIPDSRKCDRRRDCADGSDEEECEGVCGRNEFRCNDG-TCVERRVKCDRFVNCPDGS 634

Query: 1219 DEAGC 1223
            DE  C
Sbjct: 635  DEFDC 649

 Score = 25.4 bits (54), Expect(3) = 4e-18,   Method: Composition-based stats.
 Identities = 17/40 (42%), Positives = 21/40 (52%)
 Frame = +3

Query: 1118 DNHMCIPKEWVCDTDNDCSDGSDEKNCQASGTCHPTQFRC 1157
            D+ +CI     CD   DC DGSDE+ C     C   +FRC
Sbjct: 348  DSGLCIDLARRCDRRRDCEDGSDEERC----PCLANEFRC 455

 Score = 91.3 bits (225), Expect = 8e-18,   Method: Compositional matrix adjust.
 Identities = 53/113 (46%), Positives = 67/113 (59%)
 Frame = +1

Query: 2999 EFSCANGRCIRQSFRCDRRNDCGDYSDERGCSYPPCRDDQFTCQNGQCITKLYVCDEDND 3058
            +F C +G CI    RCD   DC D SDE  C   PCRDDQF+C++G CI   + C+   +
Sbjct: 1    DFECEDGSCIDNRLRCDGVPDCSDRSDESNC---PCRDDQFSCRDGLCIEAEFRCNGRVE 171

Query: 3059 CGDGSDEQEHLCHTPEPTCPPHQFRCDNGHCIEMGTVCNHVDDCSDNSDEKGC 3111
            C DGSDE+E     P  TC   +F CD+G C+++   CN V DC D SDEK C
Sbjct: 172  CEDGSDEEE----CPRRTCSFAEFTCDDGQCVDLRDQCNQVTDCQDGSDEKNC 318

 Score = 89.4 bits (220), Expect(2) = 1e-17,   Method: Compositional matrix adjust.
 Identities = 55/117 (47%), Positives = 72/117 (61%)
 Frame = +1

Query: 1193 FKCADGSSCINSRYRCDGVYDCKDNSDEAGCPTRPPGMCHPDEFQCQGDGTCIPNTWECD 1252
            F+C DGS CI++R RCDGV DC D SDE+ CP      C  D+F C+ DG CI   + C+
Sbjct: 4    FECEDGS-CIDNRLRCDGVPDCSDRSDESNCP------CRDDQFSCR-DGLCIEAEFRCN 159

Query: 1253 GHPDCIQGSDEHNGCVPKTCSPSHFLCDNGNCIYNSWVCDGDNDCRDMSDEKDCPTQ 1309
            G  +C  GSDE   C  +TCS + F CD+G C+     C+   DC+D SDEK+CP +
Sbjct: 160  GRVECEDGSDEEE-CPRRTCSFAEFTCDDGQCVDLRDQCNQVTDCQDGSDEKNCPAE 327

 Score = 21.6 bits (44), Expect(2) = 1e-17,   Method: Composition-based stats.
 Identities = 12/33 (36%), Positives = 19/33 (57%)
 Frame = +3

Query: 1313 CPSSQWQCPGYSICVNLSALCDGVFDCPNGTDE 1345
            C   Q+ C    +C++L+  CD   DC +G+DE
Sbjct: 321  CRDDQFTCQDSGLCIDLARRCDRRRDCEDGSDE 419

 Score = 54.7 bits (130), Expect(3) = 2e-17,   Method: Compositional matrix adjust.
 Identities = 37/109 (33%), Positives = 58/109 (53%)
 Frame = +1

Query: 3560 FQCRDGNCTSPQALCNARQDCADGSDEDRVLCEHHRCEANEWQCANKRCIPEYWQCDSVD 3619
            F+C DG+C   +  C+   DC+D SDE    C       +++ C +  CI   ++C+   
Sbjct: 4    FECEDGSCIDNRLRCDGVPDCSDRSDESNCPCRD-----DQFSCRDGLCIEAEFRCNGRV 168

Query: 3620 DCLDNSDEDPSHCASRTCRPGQFKCNNGRCIPQSWKCDVDNDCGDYSDE 3668
            +C D SDE+   C  RTC   +F C++G+C+    +C+   DC D SDE
Sbjct: 169  ECEDGSDEE--ECPRRTCSFAEFTCDDGQCVDLRDQCNQVTDCQDGSDE 309

 Score = 48.1 bits (113), Expect(3) = 2e-17,   Method: Compositional matrix adjust.
 Identities = 31/63 (49%), Positives = 35/63 (55%)
 Frame = +2

Query: 3733 HCIPLRWKCDGIDDCGDNSDEESCVPRECTESEFRCADQQCIPSRWVCDQENDCGDNSDE 3792
             CIP   KCD   DC D SDEE C    C  +EFRC D  C+  R  CD+  +C D SDE
Sbjct: 464  RCIPDSRKCDRRRDCADGSDEEECEG-VCGRNEFRCNDGTCVERRVKCDRFVNCPDGSDE 640

Query: 3793 RDC 3795
             DC
Sbjct: 641  FDC 649

 Score = 26.9 bits (58), Expect(3) = 2e-17,   Method: Composition-based stats.
 Identities = 18/46 (39%), Positives = 26/46 (56%)
 Frame = +3

Query: 3685 EFSCKTNYRCIPQWAVCNGFDDCRDNSDEQGCESVPCHPSGDFRCG 3730
            +F+C+ +  CI     C+   DC D SDE+ C   PC  + +FRCG
Sbjct: 333  QFTCQDSGLCIDLARRCDRRRDCEDGSDEERC---PCL-ANEFRCG 458

 Score = 67.0 bits (162), Expect(3) = 3e-17,   Method: Compositional matrix adjust.
 Identities = 43/114 (37%), Positives = 58/114 (50%)
 Frame = +1

Query: 2706 FTCLNGRCISQDWKXXXXXXXXXXSDELPTVCAFHTCRSTAFTCANGRCVPYHYRCDFYN 2765
            F C +G CI    +          SDE     +   CR   F+C +G C+   +RC+   
Sbjct: 4    FECEDGSCIDNRLRCDGVPDCSDRSDE-----SNCPCRDDQFSCRDGLCIEAEFRCNGRV 168

Query: 2766 DCGDNSDEAGCLFRSCNSTTEFTCSNGRCIPLSYVCNGINNCHDNDTSDEKNCP 2819
            +C D SDE  C  R+C S  EFTC +G+C+ L   CN + +C D   SDEKNCP
Sbjct: 169  ECEDGSDEEECPRRTC-SFAEFTCDDGQCVDLRDQCNQVTDCQDG--SDEKNCP 321

 Score = 40.8 bits (94), Expect(3) = 3e-17,   Method: Compositional matrix adjust.
 Identities = 26/63 (41%), Positives = 32/63 (50%)
 Frame = +2

Query: 2877 RCIPSYWFCDGEADCVDSSDEPDTCGHSLNSCSANQFHCDNGRCISSSWVCDGDNDCGDM 2936
            RCIP    CD   DC D SDE +  G     C  N+F C++G C+     CD   +C D 
Sbjct: 464  RCIPDSRKCDRRRDCADGSDEEECEG----VCGRNEFRCNDGTCVERRVKCDRFVNCPDG 631

Query: 2937 SDE 2939
            SDE
Sbjct: 632  SDE 640

 Score = 21.6 bits (44), Expect(3) = 3e-17,   Method: Composition-based stats.
 Identities = 12/52 (23%), Positives = 20/52 (38%)
 Frame = +3

Query: 2821 ITCQPDFAKCQTTNICVPRAFLXXXXXXXXXXXXENPIYCASHTCRSNEFQC 2872
            ++C+ D   CQ + +C+  A              E         C +NEF+C
Sbjct: 315  LSCRDDQFTCQDSGLCIDLARRCDRRRDCEDGSDEERC-----PCLANEFRC 455

 Score = 58.9 bits (141), Expect(2) = 6e-17,   Method: Compositional matrix adjust.
 Identities = 46/126 (36%), Positives = 61/126 (48%)
 Frame = +1

Query: 3642 FKCNNGRCIPQSWKCDVDNDCGDYSDEPIHECMTAAYNCDNHTEFSCKTNYRCIPQWAVC 3701
            F+C +G CI    +CD   DC D SDE    C           +FSC+    CI     C
Sbjct: 4    FECEDGSCIDNRLRCDGVPDCSDRSDESNCPCR--------DDQFSCRDGL-CIEAEFRC 156

Query: 3702 NGFDDCRDNSDEQGCESVPCHPSGDFRCGNHHCIPLRWKCDGIDDCGDNSDEESCVPREC 3761
            NG  +C D SDE+ C    C    +F C +  C+ LR +C+ + DC D SDE++C P E 
Sbjct: 157  NGRVECEDGSDEEECPRRTCS-FAEFTCDDGQCVDLRDQCNQVTDCQDGSDEKNC-PAEM 330

Query: 3762 TESEFR 3767
              S  R
Sbjct: 331  ISSRVR 348

 Score = 50.1 bits (118), Expect(2) = 6e-17,   Method: Compositional matrix adjust.
 Identities = 28/65 (43%), Positives = 35/65 (53%)
 Frame = +2

Query: 3770 DQQCIPSRWVCDQENDCGDNSDERDCEMKTCHPEHFQCTSGHCVPKALACDGRADCLDAS 3829
            D +CIP    CD+  DC D SDE +CE   C    F+C  G CV + + CD   +C D S
Sbjct: 458  DGRCIPDSRKCDRRRDCADGSDEEECEG-VCGRNEFRCNDGTCVERRVKCDRFVNCPDGS 634

Query: 3830 DESAC 3834
            DE  C
Sbjct: 635  DEFDC 649

 Score = 66.2 bits (160), Expect(3) = 2e-16,   Method: Compositional matrix adjust.
 Identities = 46/111 (41%), Positives = 60/111 (54%)
 Frame = +1

Query: 3685 EFSCKTNYRCIPQWAVCNGFDDCRDNSDEQGCESVPCHPSGDFRCGNHHCIPLRWKCDGI 3744
            +F C+    CI     C+G  DC D SDE  C   PC     F C +  CI   ++C+G 
Sbjct: 1    DFECEDGS-CIDNRLRCDGVPDCSDRSDESNC---PCRDDQ-FSCRDGLCIEAEFRCNGR 165

Query: 3745 DDCGDNSDEESCVPRECTESEFRCADQQCIPSRWVCDQENDCGDNSDERDC 3795
             +C D SDEE C  R C+ +EF C D QC+  R  C+Q  DC D SDE++C
Sbjct: 166  VECEDGSDEEECPRRTCSFAEFTCDDGQCVDLRDQCNQVTDCQDGSDEKNC 318

 Score = 33.1 bits (74), Expect(3) = 2e-16,   Method: Compositional matrix adjust.
 Identities = 25/65 (38%), Positives = 30/65 (46%), Gaps = 3/65 (4%)
 Frame = +2

Query: 3856 CIQSFWICDGENDCVDGSDEEIHLCFNVPCES---PQRFRCDNSRCIYGHQLCNGVDDCG 3912
            CI     CD   DC DGSDEE        CE       FRC++  C+     C+   +C 
Sbjct: 467  CIPDSRKCDRRRDCADGSDEE-------ECEGVCGRNEFRCNDGTCVERRVKCDRFVNCP 625

Query: 3913 DGSDE 3917
            DGSDE
Sbjct: 626  DGSDE 640

 Score = 26.9 bits (58), Expect(3) = 2e-16,   Method: Composition-based stats.
 Identities = 22/54 (40%), Positives = 25/54 (46%), Gaps = 1/54 (1%)
 Frame = +3

Query: 3799 TCHPEHFQCT-SGHCVPKALACDGRADCLDASDESACPTRFPNGTYCPAAMFEC 3851
            +C  + F C  SG C+  A  CD R DC D SDE  CP        C A  F C
Sbjct: 318  SCRDDQFTCQDSGLCIDLARRCDRRRDCEDGSDEERCP--------CLANEFRC 455

 Score = 56.6 bits (135), Expect(3) = 4e-16,   Method: Compositional matrix adjust.
 Identities = 43/120 (35%), Positives = 60/120 (50%), Gaps = 3/120 (2%)
 Frame = +1

Query: 3600 EWQCANKRCIPEYWQCDSVDDCLDNSDEDPSHCASRTCRPGQFKCNNGRCIPQSWKCDVD 3659
            +++C +  CI    +CD V DC D SDE  S+C    CR  QF C +G CI   ++C+  
Sbjct: 1    DFECEDGSCIDNRLRCDGVPDCSDRSDE--SNCP---CRDDQFSCRDGLCIEAEFRCNGR 165

Query: 3660 NDCGDYSDE---PIHECMTAAYNCDNHTEFSCKTNYRCIPQWAVCNGFDDCRDNSDEQGC 3716
             +C D SDE   P   C  A + CD+          +C+     CN   DC+D SDE+ C
Sbjct: 166  VECEDGSDEEECPRRTCSFAEFTCDDG---------QCVDLRDQCNQVTDCQDGSDEKNC 318

 Score = 43.1 bits (100), Expect(3) = 4e-16,   Method: Compositional matrix adjust.
 Identities = 25/66 (37%), Positives = 31/66 (46%)
 Frame = +2

Query: 3810 GHCVPKALACDGRADCLDASDESACPTRFPNGTYCPAAMFECKNHVCIQSFWICDGENDC 3869
            G C+P +  CD R DC D SDE  C         C    F C +  C++    CD   +C
Sbjct: 461  GRCIPDSRKCDRRRDCADGSDEEECEG------VCGRNEFRCNDGTCVERRVKCDRFVNC 622

Query: 3870 VDGSDE 3875
             DGSDE
Sbjct: 623  PDGSDE 640

 Score = 26.2 bits (56), Expect(3) = 4e-16,   Method: Composition-based stats.
 Identities = 11/21 (52%), Positives = 12/21 (57%)
 Frame = +3

Query: 3749 DNSDEESCVPRECTESEFRCA 3769
            D SDEE C    C  +EFRC 
Sbjct: 405  DGSDEERC---PCLANEFRCG 458

 Score = 50.1 bits (118), Expect(3) = 7e-15,   Method: Compositional matrix adjust.
 Identities = 29/72 (40%), Positives = 39/72 (54%)
 Frame = +2

Query: 3043 NGQCITKLYVCDEDNDCGDGSDEQEHLCHTPEPTCPPHQFRCDNGHCIEMGTVCNHVDDC 3102
            +G+CI     CD   DC DGSDE+E      E  C  ++FRC++G C+E    C+   +C
Sbjct: 458  DGRCIPDSRKCDRRRDCADGSDEEEC-----EGVCGRNEFRCNDGTCVERRVKCDRFVNC 622

Query: 3103 SDNSDEKGCGIN 3114
             D SDE  C  N
Sbjct: 623  PDGSDEFDCACN 658

 Score = 45.4 bits (106), Expect(3) = 7e-15,   Method: Compositional matrix adjust.
 Identities = 32/80 (40%), Positives = 41/80 (51%)
 Frame = +1

Query: 2878 CIPSYWFCDGEADCVDSSDEPDTCGHSLNSCSANQFHCDNGRCISSSWVCDGDNDCGDMS 2937
            CI +   CDG  DC D SDE +        C  +QF C +G CI + + C+G  +C D S
Sbjct: 25   CIDNRLRCDGVPDCSDRSDESNC------PCRDDQFSCRDGLCIEAEFRCNGRVECEDGS 186

Query: 2938 DEDQRHHCELQNCSSTEFTC 2957
            DE     C  + CS  EFTC
Sbjct: 187  DE---EECPRRTCSFAEFTC 237

 Score = 25.8 bits (55), Expect(3) = 7e-15,   Method: Composition-based stats.
 Identities = 22/49 (44%), Positives = 29/49 (59%), Gaps = 1/49 (2%)
 Frame = +3

Query: 2994 ACSTGEFSCAN-GRCIRQSFRCDRRNDCGDYSDERGCSYPPCRDDQFTC 3041
            +C   +F+C + G CI  + RCDRR DC D SDE  C   PC  ++F C
Sbjct: 318  SCRDDQFTCQDSGLCIDLARRCDRRRDCEDGSDEERC---PCLANEFRC 455

 Score = 72.4 bits (176), Expect(2) = 3e-14,   Method: Compositional matrix adjust.
 Identities = 44/105 (41%), Positives = 60/105 (57%), Gaps = 2/105 (1%)
 Frame = +1

Query: 77  EGTCIPSSWVCDQDKDCSDGADEQQNCPGTTCSSQQLTCSNGQCVPIEYRCDHVSDCPDG 136
           +G+CI +   CD   DCSD +DE  NCP   C   Q +C +G C+  E+RC+   +C DG
Sbjct: 16  DGSCIDNRLRCDGVPDCSDRSDES-NCP---CRDDQFSCRDGLCIEAEFRCNGRVECEDG 183

Query: 137 SDERNCYYPTCD--QLTCANGACYNTSQKCDHKVDCRDSSDEANC 179
           SDE  C   TC   + TC +G C +   +C+   DC+D SDE NC
Sbjct: 184 SDEEECPRRTCSFAEFTCDDGQCVDLRDQCNQVTDCQDGSDEKNC 318

 Score = 26.9 bits (58), Expect(2) = 3e-14,   Method: Composition-based stats.
 Identities = 21/48 (43%), Positives = 24/48 (50%), Gaps = 1/48 (2%)
 Frame = +3

Query: 183 CSQKEFQC-GSGECILRAYVCDHDNDCEDNSDEHNCNYDTCGGHQFTC 229
           C   +F C  SG CI  A  CD   DCED SDE  C    C  ++F C
Sbjct: 321 CRDDQFTCQDSGLCIDLARRCDRRRDCEDGSDEERC---PCLANEFRC 455

 Score = 62.8 bits (151), Expect(2) = 1e-13,   Method: Compositional matrix adjust.
 Identities = 44/117 (37%), Positives = 57/117 (48%)
 Frame = +1

Query: 1030 FPCNNGKCVPSIFRCDGVDDCHDNSDEHQCGALNNTCSSSAFTCVHGGQCIPGQWRCDKQ 1089
            F C +G C+ +  RCDGV DC D SDE  C      C    F+C   G CI  ++RC+ +
Sbjct: 4    FECEDGSCIDNRLRCDGVPDCSDRSDESNC-----PCRDDQFSC-RDGLCIEAEFRCNGR 165

Query: 1090 NDCLDGSDEQNXXXXXXXXXXXXXXXXXDNHMCIPKEWVCDTDNDCSDGSDEKNCQA 1146
             +C DGSDE+                  D+  C+     C+   DC DGSDEKNC A
Sbjct: 166  VECEDGSDEEE----CPRRTCSFAEFTCDDGQCVDLRDQCNQVTDCQDGSDEKNCPA 324

 Score = 35.0 bits (79), Expect(2) = 1e-13,   Method: Composition-based stats.
 Identities = 23/53 (43%), Positives = 28/53 (52%)
 Frame = +3

Query: 1186 LNCTSSQFKCADGSSCINSRYRCDGVYDCKDNSDEAGCPTRPPGMCHPDEFQC 1238
            L+C   QF C D   CI+   RCD   DC+D SDE  CP      C  +EF+C
Sbjct: 315  LSCRDDQFTCQDSGLCIDLARRCDRRRDCEDGSDEERCP------CLANEFRC 455

 Score = 52.0 bits (123), Expect(3) = 5e-12,   Method: Compositional matrix adjust.
 Identities = 30/66 (45%), Positives = 36/66 (54%)
 Frame = +2

Query: 1122 CIPKEWVCDTDNDCSDGSDEKNCQASGTCHPTQFRCPDHRCISPLYVCDGDKDCVDGSDE 1181
            CIP    CD   DC+DGSDE+ C+  G C   +FRC D  C+     CD   +C DGSDE
Sbjct: 467  CIPDSRKCDRRRDCADGSDEEECE--GVCGRNEFRCNDGTCVERRVKCDRFVNCPDGSDE 640

Query: 1182 AGCVLN 1187
              C  N
Sbjct: 641  FDCACN 658

 Score = 35.4 bits (80), Expect(3) = 5e-12,   Method: Compositional matrix adjust.
 Identities = 19/49 (38%), Positives = 27/49 (55%)
 Frame = +1

Query: 1013 EGDPAREPPTQQCGSSSFPCNNGKCVPSIFRCDGVDDCHDNSDEHQCGA 1061
            +G    E P + C  + F C++G+CV    +C+ V DC D SDE  C A
Sbjct: 178  DGSDEEECPRRTCSFAEFTCDDGQCVDLRDQCNQVTDCQDGSDEKNCPA 324

 Score = 23.5 bits (49), Expect(3) = 5e-12,   Method: Composition-based stats.
 Identities = 17/35 (48%), Positives = 21/35 (60%)
 Frame = +3

Query: 1065 TCSSSAFTCVHGGQCIPGQWRCDKQNDCLDGSDEQ 1099
            +C    FTC   G CI    RCD++ DC DGSDE+
Sbjct: 318  SCRDDQFTCQDSGLCIDLARRCDRRRDCEDGSDEE 422

 Score = 71.2 bits (173), Expect = 9e-12,   Method: Compositional matrix adjust.
 Identities = 44/106 (41%), Positives = 56/106 (52%), Gaps = 1/106 (0%)
 Frame = +1

Query: 113 LTCSNGQCVPIEYRCDHVSDCPDGSDERNCYYPTCDQLTCANGACYNTSQKCDHKVDCRD 172
             C +G C+    RCD V DC D SDE NC     DQ +C +G C     +C+ +V+C D
Sbjct: 4   FECEDGSCIDNRLRCDGVPDCSDRSDESNCPCRD-DQFSCRDGLCIEAEFRCNGRVECED 180

Query: 173 SSDEANC-TTLCSQKEFQCGSGECILRAYVCDHDNDCEDNSDEHNC 217
            SDE  C    CS  EF C  G+C+     C+   DC+D SDE NC
Sbjct: 181 GSDEEECPRRTCSFAEFTCDDGQCVDLRDQCNQVTDCQDGSDEKNC 318

 Score = 67.8 bits (164), Expect(2) = 2e-11,   Method: Compositional matrix adjust.
 Identities = 44/112 (39%), Positives = 55/112 (49%)
 Frame = +1

Query: 3765 EFRCADQQCIPSRWVCDQENDCGDNSDERDCEMKTCHPEHFQCTSGHCVPKALACDGRAD 3824
            +F C D  CI +R  CD   DC D SDE +C    C  + F C  G C+     C+GR +
Sbjct: 1    DFECEDGSCIDNRLRCDGVPDCSDRSDESNC---PCRDDQFSCRDGLCIEAEFRCNGRVE 171

Query: 3825 CLDASDESACPTRFPNGTYCPAAMFECKNHVCIQSFWICDGENDCVDGSDEE 3876
            C D SDE  CP R      C  A F C +  C+     C+   DC DGSDE+
Sbjct: 172  CEDGSDEEECPRR-----TCSFAEFTCDDGQCVDLRDQCNQVTDCQDGSDEK 312

 Score = 22.3 bits (46), Expect(2) = 2e-11,   Method: Composition-based stats.
 Identities = 11/25 (44%), Positives = 13/25 (52%)
 Frame = +3

Query: 3913 DGSDEKEEHCRKPTHKPCTDTEYKC 3937
            DGSD  EE C      PC   E++C
Sbjct: 405  DGSD--EERC------PCLANEFRC 455

 Score = 55.5 bits (132), Expect(2) = 2e-09,   Method: Compositional matrix adjust.
 Identities = 48/154 (31%), Positives = 61/154 (39%)
 Frame = +1

Query: 2913 FHCDNGRCISSSWVCDGDNDCGDMSDEDQRHHCELQNCSSTEFTCINSRPPNRRCIPQHW 2972
            F C++G CI +   CDG  DC D SDE                                 
Sbjct: 4    FECEDGSCIDNRLRCDGVPDCSDRSDE--------------------------------- 84

Query: 2973 VXXXXXXXXXXXXELQNCTMRACSTGEFSCANGRCIRQSFRCDRRNDCGDYSDERGCSYP 3032
                            NC    C   +FSC +G CI   FRC+ R +C D SDE  C   
Sbjct: 85   ---------------SNC---PCRDDQFSCRDGLCIEAEFRCNGRVECEDGSDEEECPRR 210

Query: 3033 PCRDDQFTCQNGQCITKLYVCDEDNDCGDGSDEQ 3066
             C   +FTC +GQC+     C++  DC DGSDE+
Sbjct: 211  TCSFAEFTCDDGQCVDLRDQCNQVTDCQDGSDEK 312

 Score = 28.1 bits (61), Expect(2) = 2e-09,   Method: Composition-based stats.
 Identities = 17/39 (43%), Positives = 23/39 (58%), Gaps = 1/39 (2%)
 Frame = +3

Query: 3074 EPTCPPHQFRC-DNGHCIEMGTVCNHVDDCSDNSDEKGC 3111
            E +C   QF C D+G CI++   C+   DC D SDE+ C
Sbjct: 312  ELSCRDDQFTCQDSGLCIDLARRCDRRRDCEDGSDEERC 428

 Score = 63.9 bits (154), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 47/116 (40%), Positives = 58/116 (50%)
 Frame = +1

Query: 3849 FECKNHVCIQSFWICDGENDCVDGSDEEIHLCFNVPCESPQRFRCDNSRCIYGHQLCNGV 3908
            FEC++  CI +   CDG  DC D SDE      N PC   Q F C +  CI     CNG 
Sbjct: 4    FECEDGSCIDNRLRCDGVPDCSDRSDES-----NCPCRDDQ-FSCRDGLCIEAEFRCNGR 165

Query: 3909 DDCGDGSDEKEEHCRKPTHKPCTDTEYKCSNGNCVSQHYVCDNVDDCGDLSDETGC 3964
             +C DGSDE+E        + C+  E+ C +G CV     C+ V DC D SDE  C
Sbjct: 166  VECEDGSDEEE-----CPRRTCSFAEFTCDDGQCVDLRDQCNQVTDCQDGSDEKNC 318

 Score = 62.0 bits (149), Expect(2) = 2e-09,   Method: Compositional matrix adjust.
 Identities = 35/87 (40%), Positives = 48/87 (55%)
 Frame = +1

Query: 150 LTCANGACYNTSQKCDHKVDCRDSSDEANCTTLCSQKEFQCGSGECILRAYVCDHDNDCE 209
             C +G+C +   +CD   DC D SDE+NC   C   +F C  G CI   + C+   +CE
Sbjct: 4   FECEDGSCIDNRLRCDGVPDCSDRSDESNCP--CRDDQFSCRDGLCIEAEFRCNGRVECE 177

Query: 210 DNSDEHNCNYDTCGGHQFTCSNGQCIN 236
           D SDE  C   TC   +FTC +GQC++
Sbjct: 178 DGSDEEECPRRTCSFAEFTCDDGQCVD 258

 Score = 21.6 bits (44), Expect(2) = 2e-09,   Method: Composition-based stats.
 Identities = 17/57 (29%), Positives = 25/57 (43%)
 Frame = +3

Query: 264 TCYPREWACPGSGRCISMDKVCDGVPDCPEGEDENNATSGRYCGTGLCSILNCEYQC 320
           +C   ++ C  SG CI + + CD   DC +G DE             C  L  E++C
Sbjct: 318 SCRDDQFTCQDSGLCIDLARRCDRRRDCEDGSDEER-----------CPCLANEFRC 455

 Score = 59.3 bits (142), Expect(2) = 9e-09,   Method: Compositional matrix adjust.
 Identities = 30/66 (45%), Positives = 43/66 (65%)
 Frame = +2

Query: 77  EGTCIPSSWVCDQDKDCSDGADEQQNCPGTTCSSQQLTCSNGQCVPIEYRCDHVSDCPDG 136
           +G CIP S  CD+ +DC+DG+DE++ C G  C   +  C++G CV    +CD   +CPDG
Sbjct: 458 DGRCIPDSRKCDRRRDCADGSDEEE-CEGV-CGRNEFRCNDGTCVERRVKCDRFVNCPDG 631

Query: 137 SDERNC 142
           SDE +C
Sbjct: 632 SDEFDC 649

 Score = 21.9 bits (45), Expect(2) = 9e-09,   Method: Composition-based stats.
 Identities = 21/48 (43%), Positives = 25/48 (52%), Gaps = 1/48 (2%)
 Frame = +3

Query: 28  CGSGNFRC-DNGYCIPASWRCDGTRDCLDDTDEIGCPPRSCGSGFFLC 74
           C    F C D+G CI  + RCD  RDC D +DE  CP   C +  F C
Sbjct: 321 CRDDQFTCQDSGLCIDLARRCDRRRDCEDGSDEERCP---CLANEFRC 455

 Score = 57.0 bits (136), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 32/73 (43%), Positives = 41/73 (56%)
 Frame = +1

Query: 3514 CSSTQFLCGNNEKCIPIWWKCDGQKDCSDGSDESDLCPHRFCRLGQFQCRDGNCTSPQAL 3573
            C   QF C +   CI   ++C+G+ +C DGSDE + CP R C   +F C DG C   +  
Sbjct: 97   CRDDQFSCRDG-LCIEAEFRCNGRVECEDGSDEEE-CPRRTCSFAEFTCDDGQCVDLRDQ 270

Query: 3574 CNARQDCADGSDE 3586
            CN   DC DGSDE
Sbjct: 271  CNQVTDCQDGSDE 309

 Score = 43.9 bits (102), Expect(2) = 4e-07,   Method: Compositional matrix adjust.
 Identities = 26/62 (41%), Positives = 35/62 (56%)
 Frame = +2

Query: 3607 RCIPEYWQCDSVDDCLDNSDEDPSHCASRTCRPGQFKCNNGRCIPQSWKCDVDNDCGDYS 3666
            RCIP+  +CD   DC D SDE+        C   +F+CN+G C+ +  KCD   +C D S
Sbjct: 464  RCIPDSRKCDRRRDCADGSDEEECE---GVCGRNEFRCNDGTCVERRVKCDRFVNCPDGS 634

Query: 3667 DE 3668
            DE
Sbjct: 635  DE 640

 Score = 31.6 bits (70), Expect(2) = 4e-07,   Method: Composition-based stats.
 Identities = 23/51 (45%), Positives = 29/51 (56%), Gaps = 1/51 (1%)
 Frame = +3

Query: 3555 CRLGQFQCRD-GNCTSPQALCNARQDCADGSDEDRVLCEHHRCEANEWQCA 3604
            CR  QF C+D G C      C+ R+DC DGSDE+R       C ANE++C 
Sbjct: 321  CRDDQFTCQDSGLCIDLARRCDRRRDCEDGSDEERC-----PCLANEFRCG 458

 Score = 52.8 bits (125), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 43/124 (34%), Positives = 56/124 (45%)
 Frame = +1

Query: 1071 FTCVHGGQCIPGQWRCDKQNDCLDGSDEQNXXXXXXXXXXXXXXXXXDNHMCIPKEWVCD 1130
            F C   G CI  + RCD   DC D SDE N                  + +CI  E+ C+
Sbjct: 4    FEC-EDGSCIDNRLRCDGVPDCSDRSDESNCPCRDDQFSCR-------DGLCIEAEFRCN 159

Query: 1131 TDNDCSDGSDEKNCQASGTCHPTQFRCPDHRCISPLYVCDGDKDCVDGSDEAGCVLNCTS 1190
               +C DGSDE+ C    TC   +F C D +C+     C+   DC DGSDE  C     S
Sbjct: 160  GRVECEDGSDEEEC-PRRTCSFAEFTCDDGQCVDLRDQCNQVTDCQDGSDEKNCPAEMIS 336

Query: 1191 SQFK 1194
            S+ +
Sbjct: 337  SRVR 348

 Score = 44.3 bits (103), Expect(3) = 6e-06,   Method: Compositional matrix adjust.
 Identities = 27/76 (35%), Positives = 36/76 (47%)
 Frame = +1

Query: 2701 CNQFQFTCLNGRCISQDWKXXXXXXXXXXSDELPTVCAFHTCRSTAFTCANGRCVPYHYR 2760
            C   QF+C +G CI  +++          SDE    C   TC    FTC +G+CV    +
Sbjct: 97   CRDDQFSCRDGLCIEAEFRCNGRVECEDGSDE--EECPRRTCSFAEFTCDDGQCVDLRDQ 270

Query: 2761 CDFYNDCGDNSDEAGC 2776
            C+   DC D SDE  C
Sbjct: 271  CNQVTDCQDGSDEKNC 318

 Score = 24.3 bits (51), Expect(3) = 6e-06,   Method: Composition-based stats.
 Identities = 20/56 (35%), Positives = 29/56 (51%), Gaps = 1/56 (1%)
 Frame = +3

Query: 2786 EFTCSN-GRCIPLSYVCNGINNCHDNDTSDEKNCPPITCQPDFAKCQTTNICVPRA 2840
            +FTC + G CI L+  C+   +C D   SDE+ CP   C  +  +C T    + RA
Sbjct: 333  QFTCQDSGLCIDLARRCDRRRDCEDG--SDEERCP---CLANEFRCGTVAAFLIRA 485

 Score = 21.6 bits (44), Expect(3) = 6e-06,   Method: Compositional matrix adjust.
 Identities = 14/36 (38%), Positives = 18/36 (50%)
 Frame = +2

Query: 2864 TCRSNEFQCVSPHRCIPSYWFCDGEADCVDSSDEPD 2899
             C  NEF+C +   C+     CD   +C D SDE D
Sbjct: 542  VCGRNEFRC-NDGTCVERRVKCDRFVNCPDGSDEFD 646

 Score = 41.6 bits (96), Expect(2) = 2e-05,   Method: Compositional matrix adjust.
 Identities = 25/64 (39%), Positives = 34/64 (53%)
 Frame = +2

Query: 3564 DGNCTSPQALCNARQDCADGSDEDRVLCEHHRCEANEWQCANKRCIPEYWQCDSVDDCLD 3623
            DG C      C+ R+DCADGSDE+        C  NE++C +  C+    +CD   +C D
Sbjct: 458  DGRCIPDSRKCDRRRDCADGSDEEEC---EGVCGRNEFRCNDGTCVERRVKCDRFVNCPD 628

Query: 3624 NSDE 3627
             SDE
Sbjct: 629  GSDE 640

 Score = 27.7 bits (60), Expect(2) = 2e-05,   Method: Composition-based stats.
 Identities = 20/49 (40%), Positives = 29/49 (59%)
 Frame = +3

Query: 3514 CSSTQFLCGNNEKCIPIWWKCDGQKDCSDGSDESDLCPHRFCRLGQFQC 3562
            C   QF C ++  CI +  +CD ++DC DGSDE + CP   C   +F+C
Sbjct: 321  CRDDQFTCQDSGLCIDLARRCDRRRDCEDGSDE-ERCP---CLANEFRC 455

 Score = 48.9 bits (115), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 30/68 (44%), Positives = 40/68 (58%)
 Frame = +2

Query: 3004 NGRCIRQSFRCDRRNDCGDYSDERGCSYPPCRDDQFTCQNGQCITKLYVCDEDNDCGDGS 3063
            +GRCI  S +CDRR DC D SDE  C    C  ++F C +G C+ +   CD   +C DGS
Sbjct: 458  DGRCIPDSRKCDRRRDCADGSDEEECE-GVCGRNEFRCNDGTCVERRVKCDRFVNCPDGS 634

Query: 3064 DEQEHLCH 3071
            DE +  C+
Sbjct: 635  DEFDCACN 658

 Score = 48.5 bits (114), Expect = 6e-05,   Method: Compositional matrix adjust.
 Identities = 26/61 (42%), Positives = 36/61 (59%)
 Frame = +2

Query: 3526 KCIPIWWKCDGQKDCSDGSDESDLCPHRFCRLGQFQCRDGNCTSPQALCNARQDCADGSD 3585
            +CIP   KCD ++DC+DGSDE +      C   +F+C DG C   +  C+   +C DGSD
Sbjct: 464  RCIPDSRKCDRRRDCADGSDEEEC--EGVCGRNEFRCNDGTCVERRVKCDRFVNCPDGSD 637

Query: 3586 E 3586
            E
Sbjct: 638  E 640

 Score = 46.6 bits (109), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 37/113 (32%), Positives = 48/113 (42%)
 Frame = +1

Query: 187 EFQCGSGECILRAYVCDHDNDCEDNSDEHNCNYDTCGGHQFTCSNGQCINQNWVXXXXXX 246
           +F+C  G CI     CD   DC D SDE NC    C   QF+C +G CI   +       
Sbjct: 1   DFECEDGSCIDNRLRCDGVPDCSDRSDESNC---PCRDDQFSCRDGLCIEAEF----RCN 159

Query: 247 XXXXXXXXXXESNQRHHTCYPREWACPGSGRCISMDKVCDGVPDCPEGEDENN 299
                     E      TC   E+ C   G+C+ +   C+ V DC +G DE N
Sbjct: 160 GRVECEDGSDEEECPRRTCSFAEFTCD-DGQCVDLRDQCNQVTDCQDGSDEKN 315

 Score = 46.2 bits (108), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 27/66 (40%), Positives = 36/66 (54%), Gaps = 2/66 (3%)
 Frame = +2

Query: 117 NGQCVPIEYRCDHVSDCPDGSDERNCYYPTC--DQLTCANGACYNTSQKCDHKVDCRDSS 174
           +G+C+P   +CD   DC DGSDE  C    C  ++  C +G C     KCD  V+C D S
Sbjct: 458 DGRCIPDSRKCDRRRDCADGSDEEECE-GVCGRNEFRCNDGTCVERRVKCDRFVNCPDGS 634

Query: 175 DEANCT 180
           DE +C 
Sbjct: 635 DEFDCA 652

 Score = 45.1 bits (105), Expect = 6e-04,   Method: Compositional matrix adjust.
 Identities = 27/69 (39%), Positives = 38/69 (55%)
 Frame = +1

Query: 1277 FLCDNGNCIYNSWVCDGDNDCRDMSDEKDCPTQPFHCPSSQWQCPGYSICVNLSALCDGV 1336
            F C++G+CI N   CDG  DC D SDE +CP     C   Q+ C    +C+     C+G 
Sbjct: 4    FECEDGSCIDNRLRCDGVPDCSDRSDESNCP-----CRDDQFSCRD-GLCIEAEFRCNGR 165

Query: 1337 FDCPNGTDE 1345
             +C +G+DE
Sbjct: 166  VECEDGSDE 192

 Score = 44.7 bits (104), Expect = 8e-04,   Method: Compositional matrix adjust.
 Identities = 28/63 (44%), Positives = 36/63 (57%)
 Frame = +2

Query: 37  NGYCIPASWRCDGTRDCLDDTDEIGCPPRSCGSGFFLCPAEGTCIPSSWVCDQDKDCSDG 96
           +G CIP S +CD  RDC D +DE  C    CG   F C  +GTC+     CD+  +C DG
Sbjct: 458 DGRCIPDSRKCDRRRDCADGSDEEECEG-VCGRNEFRC-NDGTCVERRVKCDRFVNCPDG 631

Query: 97  ADE 99
           +DE
Sbjct: 632 SDE 640

 Score = 44.3 bits (103), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 25/65 (38%), Positives = 38/65 (58%)
 Frame = +2

Query: 1034 NGKCVPSIFRCDGVDDCHDNSDEHQCGALNNTCSSSAFTCVHGGQCIPGQWRCDKQNDCL 1093
            +G+C+P   +CD   DC D SDE +C  +   C  + F C + G C+  + +CD+  +C 
Sbjct: 458  DGRCIPDSRKCDRRRDCADGSDEEECEGV---CGRNEFRC-NDGTCVERRVKCDRFVNCP 625

Query: 1094 DGSDE 1098
            DGSDE
Sbjct: 626  DGSDE 640

 Score = 43.9 bits (102), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 42/154 (27%), Positives = 61/154 (39%)
 Frame = +1

Query: 2786 EFTCSNGRCIPLSYVCNGINNCHDNDTSDEKNCPPITCQPDFAKCQTTNICVPRAFLXXX 2845
            +F C +G CI     C+G+ +C  +D SDE NCP                          
Sbjct: 1    DFECEDGSCIDNRLRCDGVPDC--SDRSDESNCP-------------------------- 96

Query: 2846 XXXXXXXXXENPIYCASHTCRSNEFQCVSPHRCIPSYWFCDGEADCVDSSDEPDTCGHSL 2905
                               CR ++F C     CI + + C+G  +C D SDE +      
Sbjct: 97   -------------------CRDDQFSCRDGL-CIEAEFRCNGRVECEDGSDEEEC---PR 207

Query: 2906 NSCSANQFHCDNGRCISSSWVCDGDNDCGDMSDE 2939
             +CS  +F CD+G+C+     C+   DC D SDE
Sbjct: 208  RTCSFAEFTCDDGQCVDLRDQCNQVTDCQDGSDE 309

 Score = 40.0 bits (92), Expect = 0.022,   Method: Compositional matrix adjust.
 Identities = 26/68 (38%), Positives = 34/68 (50%)
 Frame = +2

Query: 2751 NGRCVPYHYRCDFYNDCGDNSDEAGCLFRSCNSTTEFTCSNGRCIPLSYVCNGINNCHDN 2810
            +GRC+P   +CD   DC D SDE  C         EF C++G C+     C+   NC D 
Sbjct: 458  DGRCIPDSRKCDRRRDCADGSDEEEC--EGVCGRNEFRCNDGTCVERRVKCDRFVNCPDG 631

Query: 2811 DTSDEKNC 2818
              SDE +C
Sbjct: 632  --SDEFDC 649

 Score = 39.7 bits (91), Expect = 0.030,   Method: Compositional matrix adjust.
 Identities = 29/71 (40%), Positives = 34/71 (47%)
 Frame = +2

Query: 3646 NGRCIPQSWKCDVDNDCGDYSDEPIHECMTAAYNCDNHTEFSCKTNYRCIPQWAVCNGFD 3705
            +GRCIP S KCD   DC D SDE   EC           EF C     C+ +   C+ F 
Sbjct: 458  DGRCIPDSRKCDRRRDCADGSDE--EECEGVC----GRNEFRCNDGT-CVERRVKCDRFV 616

Query: 3706 DCRDNSDEQGC 3716
            +C D SDE  C
Sbjct: 617  NCPDGSDEFDC 649

 Score = 37.7 bits (86), Expect = 0.11,   Method: Compositional matrix adjust.
 Identities = 24/65 (36%), Positives = 35/65 (53%)
 Frame = +2

Query: 1281 NGNCIYNSWVCDGDNDCRDMSDEKDCPTQPFHCPSSQWQCPGYSICVNLSALCDGVFDCP 1340
            +G CI +S  CD   DC D SDE++C      C  ++++C     CV     CD   +CP
Sbjct: 458  DGRCIPDSRKCDRRRDCADGSDEEECEGV---CGRNEFRC-NDGTCVERRVKCDRFVNCP 625

Query: 1341 NGTDE 1345
            +G+DE
Sbjct: 626  DGSDE 640

 Score = 30.0 bits (66), Expect(2) = 0.28,   Method: Compositional matrix adjust.
 Identities = 15/37 (40%), Positives = 21/37 (56%)
 Frame = +2

Query: 2994 ACSTGEFSCANGRCIRQSFRCDRRNDCGDYSDERGCS 3030
             C   EF C +G C+ +  +CDR  +C D SDE  C+
Sbjct: 542  VCGRNEFRCNDGTCVERRVKCDRFVNCPDGSDEFDCA 652

 Score = 25.0 bits (53), Expect(2) = 0.28,   Method: Composition-based stats.
 Identities = 22/52 (42%), Positives = 28/52 (53%), Gaps = 1/52 (1%)
 Frame = +3

Query: 2907 SCSANQFHC-DNGRCISSSWVCDGDNDCGDMSDEDQRHHCELQNCSSTEFTC 2957
            SC  +QF C D+G CI  +  CD   DC D SDE++   C    C + EF C
Sbjct: 318  SCRDDQFTCQDSGLCIDLARRCDRRRDCEDGSDEER---CP---CLANEFRC 455

 Score = 36.2 bits (82), Expect = 0.28,   Method: Composition-based stats.
 Identities = 26/52 (50%), Positives = 30/52 (57%), Gaps = 1/52 (1%)
 Frame = +3

Query: 3034 CRDDQFTCQN-GQCITKLYVCDEDNDCGDGSDEQEHLCHTPEPTCPPHQFRC 3084
            CRDDQFTCQ+ G CI     CD   DC DGSDE+   C      C  ++FRC
Sbjct: 321  CRDDQFTCQDSGLCIDLARRCDRRRDCEDGSDEER--C-----PCLANEFRC 455

 Score = 35.4 bits (80), Expect = 0.49,   Method: Compositional matrix adjust.
 Identities = 18/45 (40%), Positives = 25/45 (55%)
 Frame = +2

Query: 193 GECILRAYVCDHDNDCEDNSDEHNCNYDTCGGHQFTCSNGQCINQ 237
           G CI  +  CD   DC D SDE  C    CG ++F C++G C+ +
Sbjct: 461 GRCIPDSRKCDRRRDCADGSDEEECEG-VCGRNEFRCNDGTCVER 592

 Score = 28.5 bits (62), Expect(2) = 0.72,   Method: Compositional matrix adjust.
 Identities = 22/57 (38%), Positives = 27/57 (47%)
 Frame = +2

Query: 2917 NGRCISSSWVCDGDNDCGDMSDEDQRHHCELQNCSSTEFTCINSRPPNRRCIPQHWV 2973
            +GRCI  S  CD   DC D SDE++   CE   C   EF C +     RR     +V
Sbjct: 458  DGRCIPDSRKCDRRRDCADGSDEEE---CEGV-CGRNEFRCNDGTCVERRVKCDRFV 616

 Score = 25.0 bits (53), Expect(2) = 0.72,   Method: Composition-based stats.
 Identities = 20/52 (38%), Positives = 25/52 (48%)
 Frame = +3

Query: 2864 TCRSNEFQCVSPHRCIPSYWFCDGEADCVDSSDEPDTCGHSLNSCSANQFHC 2915
            +CR ++F C     CI     CD   DC D SDE + C      C AN+F C
Sbjct: 318  SCRDDQFTCQDSGLCIDLARRCDRRRDCEDGSDE-ERC-----PCLANEFRC 455

 Score = 32.7 bits (73), Expect = 3.8,   Method: Compositional matrix adjust.
 Identities = 16/36 (44%), Positives = 20/36 (55%)
 Frame = +2

Query: 1025 CGSSSFPCNNGKCVPSIFRCDGVDDCHDNSDEHQCG 1060
            CG + F CN+G CV    +CD   +C D SDE  C 
Sbjct: 545  CGRNEFRCNDGTCVERRVKCDRFVNCPDGSDEFDCA 652

 Score = 32.0 bits (71), Expect = 6.5,   Method: Compositional matrix adjust.
 Identities = 13/31 (41%), Positives = 20/31 (64%)
 Frame = +1

Query: 3934 EYKCSNGNCVSQHYVCDNVDDCGDLSDETGC 3964
            +++C +G+C+     CD V DC D SDE+ C
Sbjct: 1    DFECEDGSCIDNRLRCDGVPDCSDRSDESNC 93
>34993
          Length = 626

 Score = 73.9 bits (180), Expect = 1e-12,   Method: Compositional matrix adjust.
 Identities = 40/91 (43%), Positives = 55/91 (60%), Gaps = 2/91 (2%)
 Frame = -2

Query: 1349 CNQDS-CLHFNGGCTHRCIQGPFGATCVCPIGYQLANDTKTCEDVNEC-DIPGFCSQHCV 1406
            C +D+ C H NGGC H C+     A C C  GY+LA D ++C+D++EC    G C Q CV
Sbjct: 307  CQEDNPCQHSNGGCQHTCVSDRGRAVCRCFQGYELAADGRSCKDIDECAKRNGDCLQRCV 128

Query: 1407 NMRGSFRCACDPEYTLESDGRTCKVTASENL 1437
            N +GSF C C   Y L +DGR+C +  + N+
Sbjct: 127  NTQGSFTCTCTQGYQLGNDGRSCYIMPAANV 35

 Score = 62.8 bits (151), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 34/80 (42%), Positives = 42/80 (52%)
 Frame = -2

Query: 3114 NECQDSSISHCDHNCTDTITSFYCSCLPGYKLMSDKRTCVDIDECKETPQLCSQKCENVI 3173
            N CQ S+   C H C        C C  GY+L +D R+C DIDEC +    C Q+C N  
Sbjct: 295  NPCQHSN-GGCQHTCVSDRGRAVCRCFQGYELAADGRSCKDIDECAKRNGDCLQRCVNTQ 119

Query: 3174 GSYICKCAPGYIREPDGKSC 3193
            GS+ C C  GY    DG+SC
Sbjct: 118  GSFTCTCTQGYQLGNDGRSC 59

 Score = 60.5 bits (145), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 33/81 (40%), Positives = 44/81 (54%), Gaps = 2/81 (2%)
 Frame = -2

Query: 1352 DSCLHFNGGCTHRCIQGPFGATCVCPIGYQLANDTKTCEDVNECDIP-GFCSQHCVN-MR 1409
            D C+  NGGC H+C+    G  C CP G +L  D +TC  V+ C +  G C   C +   
Sbjct: 544  DECVSHNGGCQHKCVNTYGGFNCECPKGQRLHVDARTCIAVSGCSVXNGGCEHVCTDGYN 365

Query: 1410 GSFRCACDPEYTLESDGRTCK 1430
            G F C C P YTL  DG++C+
Sbjct: 364  GHFHCRCRPGYTLAQDGKSCQ 302

 Score = 55.1 bits (131), Expect = 6e-07,   Method: Compositional matrix adjust.
 Identities = 30/84 (35%), Positives = 42/84 (50%), Gaps = 4/84 (4%)
 Frame = -2

Query: 3118 DSSISH---CDHNCTDTITSFYCSCLPGYKLMSDKRTCVDIDECKETPQLCSQKC-ENVI 3173
            D  +SH   C H C +T   F C C  G +L  D RTC+ +  C      C   C +   
Sbjct: 544  DECVSHNGGCQHKCVNTYGGFNCECPKGQRLHVDARTCIAVSGCSVXNGGCEHVCTDGYN 365

Query: 3174 GSYICKCAPGYIREPDGKSCRQNS 3197
            G + C+C PGY    DGKSC++++
Sbjct: 364  GHFHCRCRPGYTLAQDGKSCQEDN 293

 Score = 53.1 bits (126), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 39/99 (39%), Positives = 46/99 (46%), Gaps = 6/99 (6%)
 Frame = -2

Query: 1338 DCPNG----TDESPLCNQDSCLHFNGGCTHRCIQGPFGA-TCVCPIGYQLANDTKTCEDV 1392
            +CP G     D         C   NGGC H C  G  G   C C  GY LA D K+C++ 
Sbjct: 475  ECPKGQRLHVDARTCIAVSGCSVXNGGCEHVCTDGYNGHFHCRCRPGYTLAQDGKSCQED 296

Query: 1393 NECDIP-GFCSQHCVNMRGSFRCACDPEYTLESDGRTCK 1430
            N C    G C   CV+ RG   C C   Y L +DGR+CK
Sbjct: 295  NPCQHSNGGCQHTCVSDRGRAVCRCFQGYELAADGRSCK 179

 Score = 52.8 bits (125), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 26/72 (36%), Positives = 39/72 (54%), Gaps = 1/72 (1%)
 Frame = -2

Query: 3124 CDHNCTDTITS-FYCSCLPGYKLMSDKRTCVDIDECKETPQLCSQKCENVIGSYICKCAP 3182
            C+H CTD     F+C C PGY L  D ++C + + C+ +   C   C +  G  +C+C  
Sbjct: 394  CEHVCTDGYNGHFHCRCRPGYTLAQDGKSCQEDNPCQHSNGGCQHTCVSDRGRAVCRCFQ 215

Query: 3183 GYIREPDGKSCR 3194
            GY    DG+SC+
Sbjct: 214  GYELAADGRSCK 179

 Score = 51.6 bits (122), Expect = 7e-06,   Method: Compositional matrix adjust.
 Identities = 34/97 (35%), Positives = 43/97 (44%), Gaps = 5/97 (5%)
 Frame = -2

Query: 1374 CVCPIGYQLANDTKTCEDVNEC-DIPGFCSQHCVNMRGSFRCACDPEYTLESDGRTCKVT 1432
            C C +G++LA D K+C DV+EC    G C   CVN  G F C C     L  D RTC   
Sbjct: 601  CRCSMGFELAEDMKSCLDVDECVSHNGGCQHKCVNTYGGFNCECPKGQRLHVDARTC--I 428

Query: 1433 ASENLLLVVASRDKIIMDNITAHTHNI----YSLVQD 1465
            A     +     + +  D    H H      Y+L QD
Sbjct: 427  AVSGCSVXNGGCEHVCTDGYNGHFHCRCRPGYTLAQD 317

 Score = 48.5 bits (114), Expect = 6e-05,   Method: Compositional matrix adjust.
 Identities = 22/64 (34%), Positives = 34/64 (53%)
 Frame = -2

Query: 3130 DTITSFYCSCLPGYKLMSDKRTCVDIDECKETPQLCSQKCENVIGSYICKCAPGYIREPD 3189
            +T  S+ C C  G++L  D ++C+D+DEC      C  KC N  G + C+C  G     D
Sbjct: 622  NTAGSYRCRCSMGFELAEDMKSCLDVDECVSHNGGCQHKCVNTYGGFNCECPKGQRLHVD 443

Query: 3190 GKSC 3193
             ++C
Sbjct: 442  ARTC 431

 Score = 41.6 bits (96), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 25/64 (39%), Positives = 34/64 (53%), Gaps = 1/64 (1%)
 Frame = -2

Query: 3977 CEQNCTQLSNGGFICSCRPGFKPSTLDKNSCQDINECEEF-GICPQSCRNSKGSYECFCV 4035
            CE  CT   NG F C CRPG+  +  D  SCQ+ N C+   G C  +C + +G   C C 
Sbjct: 394  CEHVCTDGYNGHFHCRCRPGYTLAQ-DGKSCQEDNPCQHSNGGCQHTCVSDRGRAVCRCF 218

Query: 4036 DGFK 4039
             G++
Sbjct: 217  QGYE 206

 Score = 35.4 bits (80), Expect = 0.54,   Method: Compositional matrix adjust.
 Identities = 25/76 (32%), Positives = 39/76 (51%), Gaps = 3/76 (3%)
 Frame = -2

Query: 316 CEYQCHQTPYGGECFCPPGHIINSNDSRTCIDFDDCQIW-GICDQKC-ESRQGRHQCLCE 373
           C+++C  T  G  C CP G  ++  D+RTCI    C +  G C+  C +   G   C C 
Sbjct: 517 CQHKCVNTYGGFNCECPKGQRLHV-DARTCIAVSGCSVXNGGCEHVCTDGYNGHFHCRCR 341

Query: 374 EGYILER-GQHCKSND 388
            GY L + G+ C+ ++
Sbjct: 340 PGYTLAQDGKSCQEDN 293

 Score = 35.4 bits (80), Expect = 0.57,   Method: Compositional matrix adjust.
 Identities = 18/58 (31%), Positives = 28/58 (48%)
 Frame = -2

Query: 2006 RGLRVYHHRNAADSSNGCSNNPNACQQICLPVPGGMFSCACASGFKLSPDGRSCSPYN 2063
            +G R++       + +GCS     C+ +C     G F C C  G+ L+ DG+SC   N
Sbjct: 466  KGQRLHVDARTCIAVSGCSVXNGGCEHVCTDGYNGHFHCRCRPGYTLAQDGKSCQEDN 293

 Score = 32.7 bits (73), Expect = 3.1,   Method: Compositional matrix adjust.
 Identities = 31/84 (36%), Positives = 43/84 (51%), Gaps = 6/84 (7%)
 Frame = -2

Query: 311 CSILN--CEYQCHQTPYGGE--CFCPPGHIINSNDSRTCIDFDDCQIW-GICDQKCESRQ 365
           CS+ N  CE+ C    Y G   C C PG+ + + D ++C + + CQ   G C   C S +
Sbjct: 415 CSVXNGGCEHVC-TDGYNGHFHCRCRPGYTL-AQDGKSCQEDNPCQHSNGGCQHTCVSDR 242

Query: 366 GRHQCLCEEGYILER-GQHCKSND 388
           GR  C C +GY L   G+ CK  D
Sbjct: 241 GRAVCRCFQGYELAADGRSCKDID 170

 Score = 32.7 bits (73), Expect = 3.5,   Method: Compositional matrix adjust.
 Identities = 22/64 (34%), Positives = 33/64 (51%), Gaps = 1/64 (1%)
 Frame = -2

Query: 316 CEYQCHQTPYGGECFCPPGHIINSNDSRTCIDFDDC-QIWGICDQKCESRQGRHQCLCEE 374
           C++ C        C C  G+ + + D R+C D D+C +  G C Q+C + QG   C C +
Sbjct: 268 CQHTCVSDRGRAVCRCFQGYELAA-DGRSCKDIDECAKRNGDCLQRCVNTQGSFTCTCTQ 92

Query: 375 GYIL 378
           GY L
Sbjct: 91  GYQL 80
>30369
          Length = 348

 Score = 53.5 bits (127), Expect(2) = 4e-12,   Method: Compositional matrix adjust.
 Identities = 31/63 (49%), Positives = 39/63 (61%)
 Frame = -3

Query: 3003 ANGRCIRQSFRCDRRNDCGDYSDERGCSYPPCRDDQFTCQNGQCITKLYVCDEDNDCGDG 3062
             +G CI +  RCD + DC D SDE  C+   C DDQFTC +GQC+ +   CD   DC DG
Sbjct: 325  TSGICINRPLRCDGKPDCQDASDEEYCT--GCSDDQFTCLSGQCVERRNRCDGHVDCVDG 152

Query: 3063 SDE 3065
            +DE
Sbjct: 151  TDE 143

 Score = 39.3 bits (90), Expect(2) = 4e-12,   Method: Compositional matrix adjust.
 Identities = 18/44 (40%), Positives = 22/44 (50%)
 Frame = -1

Query: 3073 PEPTCPPHQFRCDNGHCIEMGTVCNHVDDCSDNSDEKGCGINEC 3116
            P  TC P Q+RC +G+CI     C+   DC    DE  C   EC
Sbjct: 132  PPVTCSPDQYRCISGNCISYAQRCDSRADCPSGDDEFNCPAREC 1

 Score = 53.5 bits (127), Expect(2) = 4e-12,   Method: Compositional matrix adjust.
 Identities = 34/85 (40%), Positives = 42/85 (49%)
 Frame = -3

Query: 1193 FKCADGSSCINSRYRCDGVYDCKDNSDEAGCPTRPPGMCHPDEFQCQGDGTCIPNTWECD 1252
             +C     CIN   RCDG  DC+D SDE  C       C  D+F C   G C+     CD
Sbjct: 337  LRCRTSGICINRPLRCDGKPDCQDASDEEYCTG-----CSDDQFTCLS-GQCVERRNRCD 176

Query: 1253 GHPDCIQGSDEHNGCVPKTCSPSHF 1277
            GH DC+ G+DE+N      C PS+ 
Sbjct: 175  GHVDCVDGTDEYN------CXPSNM 119

 Score = 38.9 bits (89), Expect(2) = 4e-12,   Method: Compositional matrix adjust.
 Identities = 18/41 (43%), Positives = 23/41 (56%)
 Frame = -1

Query: 1269 PKTCSPSHFLCDNGNCIYNSWVCDGDNDCRDMSDEKDCPTQ 1309
            P TCSP  + C +GNCI  +  CD   DC    DE +CP +
Sbjct: 129  PVTCSPDQYRCISGNCISYAQRCDSRADCPSGDDEFNCPAR 7

 Score = 44.3 bits (103), Expect(2) = 9e-11,   Method: Compositional matrix adjust.
 Identities = 27/62 (43%), Positives = 34/62 (54%)
 Frame = -3

Query: 3734 CIPLRWKCDGIDDCGDNSDEESCVPRECTESEFRCADQQCIPSRWVCDQENDCGDNSDER 3793
            CI    +CDG  DC D SDEE C    C++ +F C   QC+  R  CD   DC D +DE 
Sbjct: 313  CINRPLRCDGKPDCQDASDEEYCTG--CSDDQFTCLSGQCVERRNRCDGHVDCVDGTDEY 140

Query: 3794 DC 3795
            +C
Sbjct: 139  NC 134

 Score = 43.5 bits (101), Expect(2) = 9e-11,   Method: Compositional matrix adjust.
 Identities = 19/39 (48%), Positives = 24/39 (61%)
 Frame = -1

Query: 3799 TCHPEHFQCTSGHCVPKALACDGRADCLDASDESACPTR 3837
            TC P+ ++C SG+C+  A  CD RADC    DE  CP R
Sbjct: 123  TCSPDQYRCISGNCISYAQRCDSRADCPSGDDEFNCPAR 7

 Score = 52.8 bits (125), Expect(2) = 3e-10,   Method: Compositional matrix adjust.
 Identities = 32/71 (45%), Positives = 36/71 (50%)
 Frame = -3

Query: 72  FLCPAEGTCIPSSWVCDQDKDCSDGADEQQNCPGTTCSSQQLTCSNGQCVPIEYRCDHVS 131
             C   G CI     CD   DC D +DE+     T CS  Q TC +GQCV    RCD   
Sbjct: 337 LRCRTSGICINRPLRCDGKPDCQDASDEEY---CTGCSDDQFTCLSGQCVERRNRCDGHV 167

Query: 132 DCPDGSDERNC 142
           DC DG+DE NC
Sbjct: 166 DCVDGTDEYNC 134

 Score = 33.5 bits (75), Expect(2) = 3e-10,   Method: Compositional matrix adjust.
 Identities = 14/32 (43%), Positives = 19/32 (59%)
 Frame = -1

Query: 148 DQLTCANGACYNTSQKCDHKVDCRDSSDEANC 179
           DQ  C +G C + +Q+CD + DC    DE NC
Sbjct: 111 DQYRCISGNCISYAQRCDSRADCPSGDDEFNC 16

 Score = 50.1 bits (118), Expect(2) = 5e-10,   Method: Compositional matrix adjust.
 Identities = 28/64 (43%), Positives = 35/64 (54%)
 Frame = -3

Query: 116 SNGQCVPIEYRCDHVSDCPDGSDERNCYYPTCDQLTCANGACYNTSQKCDHKVDCRDSSD 175
           ++G C+    RCD   DC D SDE  C   + DQ TC +G C     +CD  VDC D +D
Sbjct: 325 TSGICINRPLRCDGKPDCQDASDEEYCTGCSDDQFTCLSGQCVERRNRCDGHVDCVDGTD 146

Query: 176 EANC 179
           E NC
Sbjct: 145 EYNC 134

 Score = 35.4 bits (80), Expect(2) = 5e-10,   Method: Compositional matrix adjust.
 Identities = 17/40 (42%), Positives = 20/40 (50%)
 Frame = -1

Query: 183 CSQKEFQCGSGECILRAYVCDHDNDCEDNSDEHNCNYDTC 222
           CS  +++C SG CI  A  CD   DC    DE NC    C
Sbjct: 120 CSPDQYRCISGNCISYAQRCDSRADCPSGDDEFNCPAREC 1

 Score = 53.1 bits (126), Expect(2) = 3e-09,   Method: Compositional matrix adjust.
 Identities = 31/68 (45%), Positives = 38/68 (55%)
 Frame = -3

Query: 3808 TSGHCVPKALACDGRADCLDASDESACPTRFPNGTYCPAAMFECKNHVCIQSFWICDGEN 3867
            TSG C+ + L CDG+ DC DASDE  C       T C    F C +  C++    CDG  
Sbjct: 325  TSGICINRPLRCDGKPDCQDASDEEYC-------TGCSDDQFTCLSGQCVERRNRCDGHV 167

Query: 3868 DCVDGSDE 3875
            DCVDG+DE
Sbjct: 166  DCVDGTDE 143

 Score = 29.6 bits (65), Expect(2) = 3e-09,   Method: Compositional matrix adjust.
 Identities = 13/31 (41%), Positives = 17/31 (54%)
 Frame = -1

Query: 3887 SPQRFRCDNSRCIYGHQLCNGVDDCGDGSDE 3917
            SP ++RC +  CI   Q C+   DC  G DE
Sbjct: 117  SPDQYRCISGNCISYAQRCDSRADCPSGDDE 25

 Score = 45.1 bits (105), Expect(2) = 2e-08,   Method: Compositional matrix adjust.
 Identities = 27/64 (42%), Positives = 33/64 (51%)
 Frame = -3

Query: 1121 MCIPKEWVCDTDNDCSDGSDEKNCQASGTCHPTQFRCPDHRCISPLYVCDGDKDCVDGSD 1180
            +CI +   CD   DC D SDE+ C     C   QF C   +C+     CDG  DCVDG+D
Sbjct: 316  ICINRPLRCDGKPDCQDASDEEYCTG---CSDDQFTCLSGQCVERRNRCDGHVDCVDGTD 146

Query: 1181 EAGC 1184
            E  C
Sbjct: 145  EYNC 134

 Score = 34.3 bits (77), Expect(2) = 2e-08,   Method: Compositional matrix adjust.
 Identities = 16/41 (39%), Positives = 22/41 (53%)
 Frame = -1

Query: 1186 LNCTSSQFKCADGSSCINSRYRCDGVYDCKDNSDEAGCPTR 1226
            + C+  Q++C  G+ CI+   RCD   DC    DE  CP R
Sbjct: 126  VTCSPDQYRCISGN-CISYAQRCDSRADCPSGDDEFNCPAR 7

 Score = 42.0 bits (97), Expect(2) = 4e-08,   Method: Compositional matrix adjust.
 Identities = 19/39 (48%), Positives = 22/39 (56%)
 Frame = -1

Query: 104 PGTTCSSQQLTCSNGQCVPIEYRCDHVSDCPDGSDERNC 142
           P  TCS  Q  C +G C+    RCD  +DCP G DE NC
Sbjct: 132 PPVTCSPDQYRCISGNCISYAQRCDSRADCPSGDDEFNC 16

 Score = 36.6 bits (83), Expect(2) = 4e-08,   Method: Compositional matrix adjust.
 Identities = 26/63 (41%), Positives = 30/63 (47%)
 Frame = -3

Query: 37  NGYCIPASWRCDGTRDCLDDTDEIGCPPRSCGSGFFLCPAEGTCIPSSWVCDQDKDCSDG 96
           +G CI    RCDG  DC D +DE  C    C    F C + G C+     CD   DC DG
Sbjct: 322 SGICINRPLRCDGKPDCQDASDEEYCT--GCSDDQFTCLS-GQCVERRNRCDGHVDCVDG 152

Query: 97  ADE 99
            DE
Sbjct: 151 TDE 143

 Score = 53.1 bits (126), Expect(2) = 6e-08,   Method: Compositional matrix adjust.
 Identities = 31/67 (46%), Positives = 38/67 (56%)
 Frame = -3

Query: 1034 NGKCVPSIFRCDGVDDCHDNSDEHQCGALNNTCSSSAFTCVHGGQCIPGQWRCDKQNDCL 1093
            +G C+    RCDG  DC D SDE  C      CS   FTC+ G QC+  + RCD   DC+
Sbjct: 322  SGICINRPLRCDGKPDCQDASDEEYCTG----CSDDQFTCLSG-QCVERRNRCDGHVDCV 158

Query: 1094 DGSDEQN 1100
            DG+DE N
Sbjct: 157  DGTDEYN 137

 Score = 25.0 bits (53), Expect(2) = 6e-08,   Method: Compositional matrix adjust.
 Identities = 12/25 (48%), Positives = 13/25 (52%)
 Frame = -1

Query: 1122 CIPKEWVCDTDNDCSDGSDEKNCQA 1146
            CI     CD+  DC  G DE NC A
Sbjct: 84   CISYAQRCDSRADCPSGDDEFNCPA 10

 Score = 54.3 bits (129), Expect(2) = 7e-07,   Method: Compositional matrix adjust.
 Identities = 31/65 (47%), Positives = 40/65 (61%)
 Frame = -3

Query: 153 ANGACYNTSQKCDHKVDCRDSSDEANCTTLCSQKEFQCGSGECILRAYVCDHDNDCEDNS 212
            +G C N   +CD K DC+D+SDE  CT  CS  +F C SG+C+ R   CD   DC D +
Sbjct: 325 TSGICINRPLRCDGKPDCQDASDEEYCTG-CSDDQFTCLSGQCVERRNRCDGHVDCVDGT 149

Query: 213 DEHNC 217
           DE+NC
Sbjct: 148 DEYNC 134

 Score = 20.0 bits (40), Expect(2) = 7e-07,   Method: Compositional matrix adjust.
 Identities = 7/16 (43%), Positives = 10/16 (62%)
 Frame = -1

Query: 221 TCGGHQFTCSNGQCIN 236
           TC   Q+ C +G CI+
Sbjct: 123 TCSPDQYRCISGNCIS 76

 Score = 42.7 bits (99), Expect(2) = 1e-06,   Method: Compositional matrix adjust.
 Identities = 27/73 (36%), Positives = 38/73 (52%)
 Frame = -3

Query: 3686 FSCKTNYRCIPQWAVCNGFDDCRDNSDEQGCESVPCHPSGDFRCGNHHCIPLRWKCDGID 3745
              C+T+  CI +   C+G  DC+D SDE+ C          F C +  C+  R +CDG  
Sbjct: 337  LRCRTSGICINRPLRCDGKPDCQDASDEEYCTGCS---DDQFTCLSGQCVERRNRCDGHV 167

Query: 3746 DCGDNSDEESCVP 3758
            DC D +DE +C P
Sbjct: 166  DCVDGTDEYNCXP 128

 Score = 31.2 bits (69), Expect(2) = 1e-06,   Method: Compositional matrix adjust.
 Identities = 14/43 (32%), Positives = 19/43 (44%)
 Frame = -1

Query: 3758 PRECTESEFRCADQQCIPSRWVCDQENDCGDNSDERDCEMKTC 3800
            P  C+  ++RC    CI     CD   DC    DE +C  + C
Sbjct: 129  PVTCSPDQYRCISGNCISYAQRCDSRADCPSGDDEFNCPAREC 1

 Score = 47.8 bits (112), Expect(2) = 1e-06,   Method: Compositional matrix adjust.
 Identities = 28/71 (39%), Positives = 34/71 (47%)
 Frame = -3

Query: 1236 FQCQGDGTCIPNTWECDGHPDCIQGSDEHNGCVPKTCSPSHFLCDNGNCIYNSWVCDGDN 1295
             +C+  G CI     CDG PDC   SDE        CS   F C +G C+     CDG  
Sbjct: 337  LRCRTSGICINRPLRCDGKPDCQDASDEE---YCTGCSDDQFTCLSGQCVERRNRCDGHV 167

Query: 1296 DCRDMSDEKDC 1306
            DC D +DE +C
Sbjct: 166  DCVDGTDEYNC 134

 Score = 26.2 bits (56), Expect(2) = 1e-06,   Method: Compositional matrix adjust.
 Identities = 13/36 (36%), Positives = 20/36 (55%)
 Frame = -1

Query: 1310 PFHCPSSQWQCPGYSICVNLSALCDGVFDCPNGTDE 1345
            P  C   Q++C   + C++ +  CD   DCP+G DE
Sbjct: 129  PVTCSPDQYRCISGN-CISYAQRCDSRADCPSGDDE 25

 Score = 38.5 bits (88), Expect(2) = 2e-06,   Method: Compositional matrix adjust.
 Identities = 22/46 (47%), Positives = 26/46 (56%)
 Frame = -3

Query: 192 SGECILRAYVCDHDNDCEDNSDEHNCNYDTCGGHQFTCSNGQCINQ 237
           SG CI R   CD   DC+D SDE  C    C   QFTC +GQC+ +
Sbjct: 322 SGICINRPLRCDGKPDCQDASDEEYCT--GCSDDQFTCLSGQCVER 191

 Score = 34.3 bits (77), Expect(2) = 2e-06,   Method: Compositional matrix adjust.
 Identities = 18/36 (50%), Positives = 22/36 (61%)
 Frame = -1

Query: 264 TCYPREWACPGSGRCISMDKVCDGVPDCPEGEDENN 299
           TC P ++ C  SG CIS  + CD   DCP G+DE N
Sbjct: 123 TCSPDQYRC-ISGNCISYAQRCDSRADCPSGDDEFN 19

 Score = 35.4 bits (80), Expect(2) = 2e-05,   Method: Compositional matrix adjust.
 Identities = 26/78 (33%), Positives = 32/78 (41%)
 Frame = -3

Query: 1070 AFTCVHGGQCIPGQWRCDKQNDCLDGSDEQNXXXXXXXXXXXXXXXXXDNHMCIPKEWVC 1129
            A  C   G CI    RCD + DC D SDE+                   +  C+ +   C
Sbjct: 340  ALRCRTSGICINRPLRCDGKPDCQDASDEEYCTGCSDDQFTCL------SGQCVERRNRC 179

Query: 1130 DTDNDCSDGSDEKNCQAS 1147
            D   DC DG+DE NC  S
Sbjct: 178  DGHVDCVDGTDEYNCXPS 125

 Score = 34.3 bits (77), Expect(2) = 2e-05,   Method: Compositional matrix adjust.
 Identities = 17/36 (47%), Positives = 18/36 (50%)
 Frame = -1

Query: 1149 TCHPTQFRCPDHRCISPLYVCDGDKDCVDGSDEAGC 1184
            TC P Q+RC    CIS    CD   DC  G DE  C
Sbjct: 123  TCSPDQYRCISGNCISYAQRCDSRADCPSGDDEFNC 16

 Score = 37.4 bits (85), Expect(2) = 2e-05,   Method: Compositional matrix adjust.
 Identities = 25/63 (39%), Positives = 33/63 (52%)
 Frame = -3

Query: 3855 VCIQSFWICDGENDCVDGSDEEIHLCFNVPCESPQRFRCDNSRCIYGHQLCNGVDDCGDG 3914
            +CI     CDG+ DC D SDEE    +   C   Q F C + +C+     C+G  DC DG
Sbjct: 316  ICINRPLRCDGKPDCQDASDEE----YCTGCSDDQ-FTCLSGQCVERRNRCDGHVDCVDG 152

Query: 3915 SDE 3917
            +DE
Sbjct: 151  TDE 143

 Score = 32.0 bits (71), Expect(2) = 2e-05,   Method: Compositional matrix adjust.
 Identities = 15/39 (38%), Positives = 21/39 (53%)
 Frame = -1

Query: 3930 CTDTEYKCSNGNCVSQHYVCDNVDDCGDLSDETGCNLGE 3968
            C+  +Y+C +GNC+S    CD+  DC    DE  C   E
Sbjct: 120  CSPDQYRCISGNCISYAQRCDSRADCPSGDDEFNCPARE 4

 Score = 45.1 bits (105), Expect(2) = 6e-05,   Method: Compositional matrix adjust.
 Identities = 27/62 (43%), Positives = 32/62 (51%)
 Frame = -3

Query: 3773 CIPSRWVCDQENDCGDNSDERDCEMKTCHPEHFQCTSGHCVPKALACDGRADCLDASDES 3832
            CI     CD + DC D SDE  C    C  + F C SG CV +   CDG  DC+D +DE 
Sbjct: 313  CINRPLRCDGKPDCQDASDEEYC--TGCSDDQFTCLSGQCVERRNRCDGHVDCVDGTDEY 140

Query: 3833 AC 3834
             C
Sbjct: 139  NC 134

 Score = 22.7 bits (47), Expect(2) = 6e-05,   Method: Compositional matrix adjust.
 Identities = 13/36 (36%), Positives = 15/36 (41%)
 Frame = -1

Query: 3849 FECKNHVCIQSFWICDGENDCVDGSDEEIHLCFNVP 3884
            + C +  CI     CD   DC  G DE     FN P
Sbjct: 105  YRCISGNCISYAQRCDSRADCPSGDDE-----FNCP 13

 Score = 34.7 bits (78), Expect(2) = 8e-05,   Method: Compositional matrix adjust.
 Identities = 17/41 (41%), Positives = 22/41 (53%), Gaps = 3/41 (7%)
 Frame = -1

Query: 3636 TCRPGQFKCNNGRCIPQSWKCDVDNDCGDYSDE---PIHEC 3673
            TC P Q++C +G CI  + +CD   DC    DE   P  EC
Sbjct: 123  TCSPDQYRCISGNCISYAQRCDSRADCPSGDDEFNCPAREC 1

 Score = 32.7 bits (73), Expect(2) = 8e-05,   Method: Compositional matrix adjust.
 Identities = 21/69 (30%), Positives = 35/69 (50%), Gaps = 1/69 (1%)
 Frame = -3

Query: 3560 FQCR-DGNCTSPQALCNARQDCADGSDEDRVLCEHHRCEANEWQCANKRCIPEYWQCDSV 3618
             +CR  G C +    C+ + DC D SDE+        C  +++ C + +C+    +CD  
Sbjct: 337  LRCRTSGICINRPLRCDGKPDCQDASDEEYCT----GCSDDQFTCLSGQCVERRNRCDGH 170

Query: 3619 DDCLDNSDE 3627
             DC+D +DE
Sbjct: 169  VDCVDGTDE 143

 Score = 39.7 bits (91), Expect(2) = 3e-04,   Method: Compositional matrix adjust.
 Identities = 26/68 (38%), Positives = 33/68 (48%)
 Frame = -3

Query: 3519 FLCGNNEKCIPIWWKCDGQKDCSDGSDESDLCPHRFCRLGQFQCRDGNCTSPQALCNARQ 3578
              C  +  CI    +CDG+ DC D SDE + C    C   QF C  G C   +  C+   
Sbjct: 337  LRCRTSGICINRPLRCDGKPDCQDASDE-EYCTG--CSDDQFTCLSGQCVERRNRCDGHV 167

Query: 3579 DCADGSDE 3586
            DC DG+DE
Sbjct: 166  DCVDGTDE 143

 Score = 25.8 bits (55), Expect(2) = 3e-04,   Method: Compositional matrix adjust.
 Identities = 14/42 (33%), Positives = 22/42 (52%)
 Frame = -1

Query: 3596 CEANEWQCANKRCIPEYWQCDSVDDCLDNSDEDPSHCASRTC 3637
            C  ++++C +  CI    +CDS  DC    DE   +C +R C
Sbjct: 120  CSPDQYRCISGNCISYAQRCDSRADCPSGDDE--FNCPAREC 1

 Score = 33.9 bits (76), Expect(2) = 5e-04,   Method: Compositional matrix adjust.
 Identities = 18/52 (34%), Positives = 24/52 (46%)
 Frame = -1

Query: 2995 CSTGEFSCANGRCIRQSFRCDRRNDCGDYSDERGCSYPPCRDDQFTCQNGQC 3046
            CS  ++ C +G CI  + RCD R DC            P  DD+F C   +C
Sbjct: 120  CSPDQYRCISGNCISYAQRCDSRADC------------PSGDDEFNCPAREC 1

 Score = 31.2 bits (69), Expect(2) = 5e-04,   Method: Compositional matrix adjust.
 Identities = 19/50 (38%), Positives = 26/50 (52%)
 Frame = -3

Query: 2917 NGRCISSSWVCDGDNDCGDMSDEDQRHHCELQNCSSTEFTCINSRPPNRR 2966
            +G CI+    CDG  DC D SDE+         CS  +FTC++ +   RR
Sbjct: 322  SGICINRPLRCDGKPDCQDASDEEY-----CTGCSDDQFTCLSGQCVERR 188

 Score = 32.7 bits (73), Expect(2) = 7e-04,   Method: Compositional matrix adjust.
 Identities = 16/38 (42%), Positives = 20/38 (52%), Gaps = 2/38 (5%)
 Frame = -1

Query: 3030 SYPP--CRDDQFTCQNGQCITKLYVCDEDNDCGDGSDE 3065
            + PP  C  DQ+ C +G CI+    CD   DC  G DE
Sbjct: 138  TVPPVTCSPDQYRCISGNCISYAQRCDSRADCPSGDDE 25

 Score = 31.6 bits (70), Expect(2) = 7e-04,   Method: Compositional matrix adjust.
 Identities = 15/36 (41%), Positives = 22/36 (61%)
 Frame = -3

Query: 2994 ACSTGEFSCANGRCIRQSFRCDRRNDCGDYSDERGC 3029
             CS  +F+C +G+C+ +  RCD   DC D +DE  C
Sbjct: 241  GCSDDQFTCLSGQCVERRNRCDGHVDCVDGTDEYNC 134

 Score = 33.5 bits (75), Expect(2) = 7e-04,   Method: Compositional matrix adjust.
 Identities = 20/59 (33%), Positives = 29/59 (49%), Gaps = 5/59 (8%)
 Frame = -3

Query: 1010 MTCEGDPAREPPTQQ-----CGSSSFPCNNGKCVPSIFRCDGVDDCHDNSDEHQCGALN 1063
            + C+G P  +  + +     C    F C +G+CV    RCDG  DC D +DE+ C   N
Sbjct: 298  LRCDGKPDCQDASDEEYCTGCSDDQFTCLSGQCVERRNRCDGHVDCVDGTDEYNCXPSN 122

 Score = 30.8 bits (68), Expect(2) = 7e-04,   Method: Compositional matrix adjust.
 Identities = 16/36 (44%), Positives = 19/36 (52%)
 Frame = -1

Query: 1065 TCSSSAFTCVHGGQCIPGQWRCDKQNDCLDGSDEQN 1100
            TCS   + C+  G CI    RCD + DC  G DE N
Sbjct: 123  TCSPDQYRCI-SGNCISYAQRCDSRADCPSGDDEFN 19

 Score = 34.3 bits (77), Expect(2) = 0.001,   Method: Compositional matrix adjust.
 Identities = 17/37 (45%), Positives = 20/37 (54%)
 Frame = -3

Query: 28  CGSGNFRCDNGYCIPASWRCDGTRDCLDDTDEIGCPP 64
           C    F C +G C+    RCDG  DC+D TDE  C P
Sbjct: 238 CSDDQFTCLSGQCVERRNRCDGHVDCVDGTDEYNCXP 128

 Score = 29.3 bits (64), Expect(2) = 0.001,   Method: Compositional matrix adjust.
 Identities = 17/46 (36%), Positives = 22/46 (47%)
 Frame = -1

Query: 63  PPRSCGSGFFLCPAEGTCIPSSWVCDQDKDCSDGADEQQNCPGTTC 108
           PP +C    + C   G CI  +  CD   DC  G D++ NCP   C
Sbjct: 132 PPVTCSPDQYRC-ISGNCISYAQRCDSRADCPSG-DDEFNCPAREC 1

 Score = 43.1 bits (100), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 27/70 (38%), Positives = 36/70 (51%)
 Frame = -3

Query: 2870 FQCVSPHRCIPSYWFCDGEADCVDSSDEPDTCGHSLNSCSANQFHCDNGRCISSSWVCDG 2929
             +C +   CI     CDG+ DC D+SDE          CS +QF C +G+C+     CDG
Sbjct: 337  LRCRTSGICINRPLRCDGKPDCQDASDE-----EYCTGCSDDQFTCLSGQCVERRNRCDG 173

Query: 2930 DNDCGDMSDE 2939
              DC D +DE
Sbjct: 172  HVDCVDGTDE 143

 Score = 32.7 bits (73), Expect(2) = 0.003,   Method: Compositional matrix adjust.
 Identities = 15/36 (41%), Positives = 19/36 (52%)
 Frame = -1

Query: 3551 PHRFCRLGQFQCRDGNCTSPQALCNARQDCADGSDE 3586
            P   C   Q++C  GNC S    C++R DC  G DE
Sbjct: 132  PPVTCSPDQYRCISGNCISYAQRCDSRADCPSGDDE 25

 Score = 29.6 bits (65), Expect(2) = 0.003,   Method: Compositional matrix adjust.
 Identities = 16/38 (42%), Positives = 22/38 (57%)
 Frame = -3

Query: 3514 CSSTQFLCGNNEKCIPIWWKCDGQKDCSDGSDESDLCP 3551
            CS  QF C + + C+    +CDG  DC DG+DE +  P
Sbjct: 238  CSDDQFTCLSGQ-CVERRNRCDGHVDCVDGTDEYNCXP 128

 Score = 31.6 bits (70), Expect(2) = 0.009,   Method: Compositional matrix adjust.
 Identities = 17/43 (39%), Positives = 22/43 (51%)
 Frame = -1

Query: 3719 VPCHPSGDFRCGNHHCIPLRWKCDGIDDCGDNSDEESCVPREC 3761
            V C P   +RC + +CI    +CD   DC    DE +C  REC
Sbjct: 126  VTCSP-DQYRCISGNCISYAQRCDSRADCPSGDDEFNCPAREC 1

 Score = 28.9 bits (63), Expect(2) = 0.009,   Method: Compositional matrix adjust.
 Identities = 23/71 (32%), Positives = 36/71 (50%)
 Frame = -3

Query: 3646 NGRCIPQSWKCDVDNDCGDYSDEPIHECMTAAYNCDNHTEFSCKTNYRCIPQWAVCNGFD 3705
            +G CI +  +CD   DC D SDE    C   + +     +F+C +  +C+ +   C+G  
Sbjct: 322  SGICINRPLRCDGKPDCQDASDEEY--CTGCSDD-----QFTCLSG-QCVERRNRCDGHV 167

Query: 3706 DCRDNSDEQGC 3716
            DC D +DE  C
Sbjct: 166  DCVDGTDEYNC 134

 Score = 34.7 bits (78), Expect(2) = 0.011,   Method: Compositional matrix adjust.
 Identities = 16/41 (39%), Positives = 19/41 (46%)
 Frame = -1

Query: 2741 TCRSTAFTCANGRCVPYHYRCDFYNDCGDNSDEAGCLFRSC 2781
            TC    + C +G C+ Y  RCD   DC    DE  C  R C
Sbjct: 123  TCSPDQYRCISGNCISYAQRCDSRADCPSGDDEFNCPAREC 1

 Score = 25.4 bits (54), Expect(2) = 0.011,   Method: Compositional matrix adjust.
 Identities = 14/30 (46%), Positives = 21/30 (70%)
 Frame = -3

Query: 2687 ANDNKYCVVDTGARCNQFQFTCLNGRCISQ 2716
            A+D +YC   TG  C+  QFTCL+G+C+ +
Sbjct: 265  ASDEEYC---TG--CSDDQFTCLSGQCVER 191

 Score = 37.0 bits (84), Expect(2) = 0.017,   Method: Compositional matrix adjust.
 Identities = 27/71 (38%), Positives = 36/71 (50%)
 Frame = -3

Query: 2750 ANGRCVPYHYRCDFYNDCGDNSDEAGCLFRSCNSTTEFTCSNGRCIPLSYVCNGINNCHD 2809
             +G C+    RCD   DC D SDE  C      S  +FTC +G+C+     C+G  +C D
Sbjct: 325  TSGICINRPLRCDGKPDCQDASDEEYCTG---CSDDQFTCLSGQCVERRNRCDGHVDCVD 155

Query: 2810 NDTSDEKNCPP 2820
               +DE NC P
Sbjct: 154  G--TDEYNCXP 128

 Score = 22.3 bits (46), Expect(2) = 0.017,   Method: Compositional matrix adjust.
 Identities = 8/16 (50%), Positives = 11/16 (68%)
 Frame = -1

Query: 2819 PPITCQPDFAKCQTTN 2834
            PP+TC PD  +C + N
Sbjct: 132  PPVTCSPDQYRCISGN 85

 Score = 38.9 bits (89), Expect = 0.053,   Method: Compositional matrix adjust.
 Identities = 28/68 (41%), Positives = 32/68 (47%), Gaps = 3/68 (4%)
 Frame = -3

Query: 1281 NGNCIYNSWVCDGDNDCRDMSDEK---DCPTQPFHCPSSQWQCPGYSICVNLSALCDGVF 1337
            +G CI     CDG  DC+D SDE+    C    F C S Q        CV     CDG  
Sbjct: 322  SGICINRPLRCDGKPDCQDASDEEYCTGCSDDQFTCLSGQ--------CVERRNRCDGHV 167

Query: 1338 DCPNGTDE 1345
            DC +GTDE
Sbjct: 166  DCVDGTDE 143

 Score = 37.4 bits (85), Expect = 0.12,   Method: Compositional matrix adjust.
 Identities = 18/41 (43%), Positives = 21/41 (51%)
 Frame = -1

Query: 1225 TRPPGMCHPDEFQCQGDGTCIPNTWECDGHPDCIQGSDEHN 1265
            T PP  C PD+++C   G CI     CD   DC  G DE N
Sbjct: 138  TVPPVTCSPDQYRCIS-GNCISYAQRCDSRADCPSGDDEFN 19

 Score = 37.4 bits (85), Expect = 0.13,   Method: Compositional matrix adjust.
 Identities = 18/45 (40%), Positives = 21/45 (46%)
 Frame = -1

Query: 23  VSGQECGSGNFRCDNGYCIPASWRCDGTRDCLDDTDEIGCPPRSC 67
           V    C    +RC +G CI  + RCD   DC    DE  CP R C
Sbjct: 135 VPPVTCSPDQYRCISGNCISYAQRCDSRADCPSGDDEFNCPAREC 1

 Score = 35.4 bits (80), Expect = 0.53,   Method: Compositional matrix adjust.
 Identities = 25/69 (36%), Positives = 32/69 (46%)
 Frame = -3

Query: 3043 NGQCITKLYVCDEDNDCGDGSDEQEHLCHTPEPTCPPHQFRCDNGHCIEMGTVCNHVDDC 3102
            +G CI +   CD   DC D SDE+          C   QF C +G C+E    C+   DC
Sbjct: 322  SGICINRPLRCDGKPDCQDASDEEYCT------GCSDDQFTCLSGQCVERRNRCDGHVDC 161

Query: 3103 SDNSDEKGC 3111
             D +DE  C
Sbjct: 160  VDGTDEYNC 134

 Score = 35.0 bits (79), Expect = 0.73,   Method: Compositional matrix adjust.
 Identities = 24/61 (39%), Positives = 33/61 (54%)
 Frame = -3

Query: 3608 CIPEYWQCDSVDDCLDNSDEDPSHCASRTCRPGQFKCNNGRCIPQSWKCDVDNDCGDYSD 3667
            CI    +CD   DC D SDE+  +C    C   QF C +G+C+ +  +CD   DC D +D
Sbjct: 313  CINRPLRCDGKPDCQDASDEE--YCTG--CSDDQFTCLSGQCVERRNRCDGHVDCVDGTD 146

Query: 3668 E 3668
            E
Sbjct: 145  E 143

 Score = 35.0 bits (79), Expect = 0.73,   Method: Compositional matrix adjust.
 Identities = 26/67 (38%), Positives = 34/67 (50%)
 Frame = -3

Query: 3898 CIYGHQLCNGVDDCGDGSDEKEEHCRKPTHKPCTDTEYKCSNGNCVSQHYVCDNVDDCGD 3957
            CI     C+G  DC D SDE  E+C       C+D ++ C +G CV +   CD   DC D
Sbjct: 313  CINRPLRCDGKPDCQDASDE--EYC-----TGCSDDQFTCLSGQCVERRNRCDGHVDCVD 155

Query: 3958 LSDETGC 3964
             +DE  C
Sbjct: 154  GTDEYNC 134

 Score = 32.7 bits (73), Expect = 3.8,   Method: Compositional matrix adjust.
 Identities = 16/35 (45%), Positives = 20/35 (57%)
 Frame = -3

Query: 2742 CRSTAFTCANGRCVPYHYRCDFYNDCGDNSDEAGC 2776
            C    FTC +G+CV    RCD + DC D +DE  C
Sbjct: 238  CSDDQFTCLSGQCVERRNRCDGHVDCVDGTDEYNC 134
>20820
          Length = 1328

 Score = 66.6 bits (161), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 38/90 (42%), Positives = 48/90 (53%)
 Frame = -2

Query: 61  GCPPRSCGSGFFLCPAEGTCIPSSWVCDQDKDCSDGADEQQNCPGTTCSSQQLTCSNGQC 120
            CP  SC SG   C  E  C+  S  CD+ KDC + ADE        C+S++  C  G C
Sbjct: 247 ACPEFSCPSGKTKCKTEPYCLDDSRFCDRIKDCDEFADETD----CNCTSEEFKCPAGPC 80

Query: 121 VPIEYRCDHVSDCPDGSDERNCYYPTCDQL 150
           +P+ + CD V DCPDGSDE +     CD L
Sbjct: 79  IPLTHTCDSVHDCPDGSDEAS----VCDYL 2

 Score = 57.0 bits (136), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 33/87 (37%), Positives = 47/87 (54%), Gaps = 8/87 (9%)
 Frame = -2

Query: 2987 LQNCTMRACSTGEFSCANGR--------CIRQSFRCDRRNDCGDYSDERGCSYPPCRDDQ 3038
            L N T+ + +  EFSC +G+        C+  S  CDR  DC +++DE  C+   C  ++
Sbjct: 274  LDNITITSGACPEFSCPSGKTKCKTEPYCLDDSRFCDRIKDCDEFADETDCN---CTSEE 104

Query: 3039 FTCQNGQCITKLYVCDEDNDCGDGSDE 3065
            F C  G CI   + CD  +DC DGSDE
Sbjct: 103  FKCPAGPCIPLTHTCDSVHDCPDGSDE 23

 Score = 51.6 bits (122), Expect = 7e-06,   Method: Compositional matrix adjust.
 Identities = 26/67 (38%), Positives = 41/67 (61%)
 Frame = -2

Query: 1284 CIYNSWVCDGDNDCRDMSDEKDCPTQPFHCPSSQWQCPGYSICVNLSALCDGVFDCPNGT 1343
            C+ +S  CD   DC + +DE DC     +C S +++CP    C+ L+  CD V DCP+G+
Sbjct: 190  CLDDSRFCDRIKDCDEFADETDC-----NCTSEEFKCPA-GPCIPLTHTCDSVHDCPDGS 29

Query: 1344 DESPLCN 1350
            DE+ +C+
Sbjct: 28   DEASVCD 8

 Score = 50.8 bits (120), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 35/84 (41%), Positives = 43/84 (51%), Gaps = 8/84 (9%)
 Frame = -2

Query: 1146 ASGTCHPTQFRCPDHR--------CISPLYVCDGDKDCVDGSDEAGCVLNCTSSQFKCAD 1197
             SG C   +F CP  +        C+     CD  KDC + +DE  C  NCTS +FKC  
Sbjct: 256  TSGAC--PEFSCPSGKTKCKTEPYCLDDSRFCDRIKDCDEFADETDC--NCTSEEFKCPA 89

Query: 1198 GSSCINSRYRCDGVYDCKDNSDEA 1221
            G  CI   + CD V+DC D SDEA
Sbjct: 88   G-PCIPLTHTCDSVHDCPDGSDEA 20

 Score = 50.8 bits (120), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 33/77 (42%), Positives = 40/77 (51%), Gaps = 1/77 (1%)
 Frame = -2

Query: 28  CGSGNFRCDNG-YCIPASWRCDGTRDCLDDTDEIGCPPRSCGSGFFLCPAEGTCIPSSWV 86
           C SG  +C    YC+  S  CD  +DC +  DE  C   +C S  F CPA G CIP +  
Sbjct: 229 CPSGKTKCKTEPYCLDDSRFCDRIKDCDEFADETDC---NCTSEEFKCPA-GPCIPLTHT 62

Query: 87  CDQDKDCSDGADEQQNC 103
           CD   DC DG+DE   C
Sbjct: 61  CDSVHDCPDGSDEASVC 11

 Score = 49.3 bits (116), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 29/82 (35%), Positives = 45/82 (54%), Gaps = 9/82 (10%)
 Frame = -2

Query: 147 CDQLTCANGA--------CYNTSQKCDHKVDCRDSSDEANCTTLCSQKEFQCGSGECILR 198
           C + +C +G         C + S+ CD   DC + +DE +C   C+ +EF+C +G CI  
Sbjct: 244 CPEFSCPSGKTKCKTEPYCLDDSRFCDRIKDCDEFADETDCN--CTSEEFKCPAGPCIPL 71

Query: 199 AYVCDHDNDCEDNSDEHN-CNY 219
            + CD  +DC D SDE + C+Y
Sbjct: 70  THTCDSVHDCPDGSDEASVCDY 5

 Score = 48.9 bits (115), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 29/71 (40%), Positives = 36/71 (50%), Gaps = 1/71 (1%)
 Frame = -2

Query: 3723 PSGDFRCGNH-HCIPLRWKCDGIDDCGDNSDEESCVPRECTESEFRCADQQCIPSRWVCD 3781
            PSG  +C    +C+     CD I DC + +DE  C    CT  EF+C    CIP    CD
Sbjct: 226  PSGKTKCKTEPYCLDDSRFCDRIKDCDEFADETDC---NCTSEEFKCPAGPCIPLTHTCD 56

Query: 3782 QENDCGDNSDE 3792
              +DC D SDE
Sbjct: 55   SVHDCPDGSDE 23

 Score = 48.5 bits (114), Expect = 6e-05,   Method: Compositional matrix adjust.
 Identities = 30/82 (36%), Positives = 40/82 (48%)
 Frame = -2

Query: 1186 LNCTSSQFKCADGSSCINSRYRCDGVYDCKDNSDEAGCPTRPPGMCHPDEFQCQGDGTCI 1245
             +C S + KC     C++    CD + DC + +DE  C       C  +EF+C   G CI
Sbjct: 235  FSCPSGKTKCKTEPYCLDDSRFCDRIKDCDEFADETDC------NCTSEEFKCPA-GPCI 77

Query: 1246 PNTWECDGHPDCIQGSDEHNGC 1267
            P T  CD   DC  GSDE + C
Sbjct: 76   PLTHTCDSVHDCPDGSDEASVC 11

 Score = 48.1 bits (113), Expect = 7e-05,   Method: Compositional matrix adjust.
 Identities = 27/80 (33%), Positives = 40/80 (50%), Gaps = 1/80 (1%)
 Frame = -2

Query: 3755 SCVPRECTESEFRCADQ-QCIPSRWVCDQENDCGDNSDERDCEMKTCHPEHFQCTSGHCV 3813
            +C    C   + +C  +  C+     CD+  DC + +DE DC    C  E F+C +G C+
Sbjct: 247  ACPEFSCPSGKTKCKTEPYCLDDSRFCDRIKDCDEFADETDCN---CTSEEFKCPAGPCI 77

Query: 3814 PKALACDGRADCLDASDESA 3833
            P    CD   DC D SDE++
Sbjct: 76   PLTHTCDSVHDCPDGSDEAS 17

 Score = 45.4 bits (106), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 26/68 (38%), Positives = 33/68 (48%)
 Frame = -2

Query: 3688 CKTNYRCIPQWAVCNGFDDCRDNSDEQGCESVPCHPSGDFRCGNHHCIPLRWKCDGIDDC 3747
            CKT   C+     C+   DC + +DE  C       S +F+C    CIPL   CD + DC
Sbjct: 208  CKTEPYCLDDSRFCDRIKDCDEFADETDCNCT----SEEFKCPAGPCIPLTHTCDSVHDC 41

Query: 3748 GDNSDEES 3755
             D SDE S
Sbjct: 40   PDGSDEAS 17

 Score = 45.1 bits (105), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 27/80 (33%), Positives = 40/80 (50%)
 Frame = -2

Query: 2860 CASHTCRSNEFQCVSPHRCIPSYWFCDGEADCVDSSDEPDTCGHSLNSCSANQFHCDNGR 2919
            C   +C S + +C +   C+    FCD   DC + +DE D       +C++ +F C  G 
Sbjct: 244  CPEFSCPSGKTKCKTEPYCLDDSRFCDRIKDCDEFADETDC------NCTSEEFKCPAGP 83

Query: 2920 CISSSWVCDGDNDCGDMSDE 2939
            CI  +  CD  +DC D SDE
Sbjct: 82   CIPLTHTCDSVHDCPDGSDE 23

 Score = 44.3 bits (103), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 24/61 (39%), Positives = 31/61 (50%)
 Frame = -2

Query: 1122 CIPKEWVCDTDNDCSDGSDEKNCQASGTCHPTQFRCPDHRCISPLYVCDGDKDCVDGSDE 1181
            C+     CD   DC + +DE +C     C   +F+CP   CI   + CD   DC DGSDE
Sbjct: 190  CLDDSRFCDRIKDCDEFADETDCN----CTSEEFKCPAGPCIPLTHTCDSVHDCPDGSDE 23

Query: 1182 A 1182
            A
Sbjct: 22   A 20

 Score = 43.5 bits (101), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 27/79 (34%), Positives = 40/79 (50%), Gaps = 1/79 (1%)
 Frame = -2

Query: 3591 CEHHRCEANEWQCANK-RCIPEYWQCDSVDDCLDNSDEDPSHCASRTCRPGQFKCNNGRC 3649
            C    C + + +C  +  C+ +   CD + DC + +DE   +C S      +FKC  G C
Sbjct: 244  CPEFSCPSGKTKCKTEPYCLDDSRFCDRIKDCDEFADETDCNCTSE-----EFKCPAGPC 80

Query: 3650 IPQSWKCDVDNDCGDYSDE 3668
            IP +  CD  +DC D SDE
Sbjct: 79   IPLTHTCDSVHDCPDGSDE 23

 Score = 42.7 bits (99), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 28/82 (34%), Positives = 39/82 (47%), Gaps = 1/82 (1%)
 Frame = -2

Query: 3547 SDLCPHRFCRLGQFQCR-DGNCTSPQALCNARQDCADGSDEDRVLCEHHRCEANEWQCAN 3605
            S  CP   C  G+ +C+ +  C      C+  +DC + +DE         C + E++C  
Sbjct: 253  SGACPEFSCPSGKTKCKTEPYCLDDSRFCDRIKDCDEFADETDC-----NCTSEEFKCPA 89

Query: 3606 KRCIPEYWQCDSVDDCLDNSDE 3627
              CIP    CDSV DC D SDE
Sbjct: 88   GPCIPLTHTCDSVHDCPDGSDE 23

 Score = 41.6 bits (96), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 29/79 (36%), Positives = 37/79 (46%), Gaps = 8/79 (10%)
 Frame = -2

Query: 1030 FPCNNGK--------CVPSIFRCDGVDDCHDNSDEHQCGALNNTCSSSAFTCVHGGQCIP 1081
            F C +GK        C+     CD + DC + +DE  C      C+S  F C   G CIP
Sbjct: 235  FSCPSGKTKCKTEPYCLDDSRFCDRIKDCDEFADETDCN-----CTSEEFKCP-AGPCIP 74

Query: 1082 GQWRCDKQNDCLDGSDEQN 1100
                CD  +DC DGSDE +
Sbjct: 73   LTHTCDSVHDCPDGSDEAS 17

 Score = 41.6 bits (96), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 26/77 (33%), Positives = 38/77 (49%), Gaps = 1/77 (1%)
 Frame = -2

Query: 103 CPGTTCSSQQLTC-SNGQCVPIEYRCDHVSDCPDGSDERNCYYPTCDQLTCANGACYNTS 161
           CP  +C S +  C +   C+     CD + DC + +DE +C   T ++  C  G C   +
Sbjct: 244 CPEFSCPSGKTKCKTEPYCLDDSRFCDRIKDCDEFADETDCNC-TSEEFKCPAGPCIPLT 68

Query: 162 QKCDHKVDCRDSSDEAN 178
             CD   DC D SDEA+
Sbjct: 67  HTCDSVHDCPDGSDEAS 17

 Score = 40.0 bits (92), Expect = 0.022,   Method: Compositional matrix adjust.
 Identities = 27/79 (34%), Positives = 41/79 (51%), Gaps = 8/79 (10%)
 Frame = -2

Query: 2747 FTCANGR--------CVPYHYRCDFYNDCGDNSDEAGCLFRSCNSTTEFTCSNGRCIPLS 2798
            F+C +G+        C+     CD   DC + +DE  C   +C S  EF C  G CIPL+
Sbjct: 235  FSCPSGKTKCKTEPYCLDDSRFCDRIKDCDEFADETDC---NCTSE-EFKCPAGPCIPLT 68

Query: 2799 YVCNGINNCHDNDTSDEKN 2817
            + C+ +++C D   SDE +
Sbjct: 67   HTCDSVHDCPDG--SDEAS 17

 Score = 40.0 bits (92), Expect = 0.023,   Method: Compositional matrix adjust.
 Identities = 23/64 (35%), Positives = 33/64 (51%)
 Frame = -2

Query: 3898 CIYGHQLCNGVDDCGDGSDEKEEHCRKPTHKPCTDTEYKCSNGNCVSQHYVCDNVDDCGD 3957
            C+   + C+ + DC + +DE        T   CT  E+KC  G C+   + CD+V DC D
Sbjct: 190  CLDDSRFCDRIKDCDEFADE--------TDCNCTSEEFKCPAGPCIPLTHTCDSVHDCPD 35

Query: 3958 LSDE 3961
             SDE
Sbjct: 34   GSDE 23

 Score = 39.7 bits (91), Expect = 0.032,   Method: Compositional matrix adjust.
 Identities = 26/76 (34%), Positives = 35/76 (46%)
 Frame = -2

Query: 3514 CSSTQFLCGNNEKCIPIWWKCDGQKDCSDGSDESDLCPHRFCRLGQFQCRDGNCTSPQAL 3573
            C S +  C     C+     CD  KDC + +DE+D      C   +F+C  G C      
Sbjct: 229  CPSGKTKCKTEPYCLDDSRFCDRIKDCDEFADETDC----NCTSEEFKCPAGPCIPLTHT 62

Query: 3574 CNARQDCADGSDEDRV 3589
            C++  DC DGSDE  V
Sbjct: 61   CDSVHDCPDGSDEASV 14

 Score = 38.5 bits (88), Expect = 0.062,   Method: Compositional matrix adjust.
 Identities = 27/79 (34%), Positives = 40/79 (50%), Gaps = 8/79 (10%)
 Frame = -2

Query: 3038 QFTCQNGQ--CITKLY------VCDEDNDCGDGSDEQEHLCHTPEPTCPPHQFRCDNGHC 3089
            +F+C +G+  C T+ Y       CD   DC + +DE +  C+     C   +F+C  G C
Sbjct: 238  EFSCPSGKTKCKTEPYCLDDSRFCDRIKDCDEFADETD--CN-----CTSEEFKCPAGPC 80

Query: 3090 IEMGTVCNHVDDCSDNSDE 3108
            I +   C+ V DC D SDE
Sbjct: 79   IPLTHTCDSVHDCPDGSDE 23

 Score = 37.0 bits (84), Expect = 0.20,   Method: Compositional matrix adjust.
 Identities = 25/75 (33%), Positives = 34/75 (45%), Gaps = 1/75 (1%)
 Frame = -2

Query: 3844 CPAAMFECKNH-VCIQSFWICDGENDCVDGSDEEIHLCFNVPCESPQRFRCDNSRCIYGH 3902
            CP+   +CK    C+     CD   DC + +DE    C      + + F+C    CI   
Sbjct: 229  CPSGKTKCKTEPYCLDDSRFCDRIKDCDEFADETDCNC------TSEEFKCPAGPCIPLT 68

Query: 3903 QLCNGVDDCGDGSDE 3917
              C+ V DC DGSDE
Sbjct: 67   HTCDSVHDCPDGSDE 23

 Score = 35.8 bits (81), Expect = 0.36,   Method: Compositional matrix adjust.
 Identities = 24/77 (31%), Positives = 37/77 (48%)
 Frame = -2

Query: 1227 PPGMCHPDEFQCQGDGTCIPNTWECDGHPDCIQGSDEHNGCVPKTCSPSHFLCDNGNCIY 1286
            P   C   + +C+ +  C+ ++  CD   DC + +DE +      C+   F C  G CI 
Sbjct: 241  PEFSCPSGKTKCKTEPYCLDDSRFCDRIKDCDEFADETDC----NCTSEEFKCPAGPCIP 74

Query: 1287 NSWVCDGDNDCRDMSDE 1303
             +  CD  +DC D SDE
Sbjct: 73   LTHTCDSVHDCPDGSDE 23

 Score = 35.8 bits (81), Expect = 0.39,   Method: Compositional matrix adjust.
 Identities = 16/33 (48%), Positives = 19/33 (57%)
 Frame = -2

Query: 2742 CRSTAFTCANGRCVPYHYRCDFYNDCGDNSDEA 2774
            C S  F C  G C+P  + CD  +DC D SDEA
Sbjct: 118  CTSEEFKCPAGPCIPLTHTCDSVHDCPDGSDEA 20

 Score = 35.4 bits (80), Expect = 0.51,   Method: Compositional matrix adjust.
 Identities = 28/82 (34%), Positives = 37/82 (45%), Gaps = 8/82 (9%)
 Frame = -2

Query: 3802 PEHFQCTSG--------HCVPKALACDGRADCLDASDESACPTRFPNGTYCPAAMFECKN 3853
            PE F C SG        +C+  +  CD   DC + +DE+ C         C +  F+C  
Sbjct: 241  PE-FSCPSGKTKCKTEPYCLDDSRFCDRIKDCDEFADETDCN--------CTSEEFKCPA 89

Query: 3854 HVCIQSFWICDGENDCVDGSDE 3875
              CI     CD  +DC DGSDE
Sbjct: 88   GPCIPLTHTCDSVHDCPDGSDE 23

 Score = 35.4 bits (80), Expect = 0.59,   Method: Compositional matrix adjust.
 Identities = 16/36 (44%), Positives = 21/36 (58%)
 Frame = -2

Query: 265 CYPREWACPGSGRCISMDKVCDGVPDCPEGEDENNA 300
           C   E+ CP +G CI +   CD V DCP+G DE + 
Sbjct: 118 CTSEEFKCP-AGPCIPLTHTCDSVHDCPDGSDEASV 14

 Score = 35.4 bits (80), Expect = 0.61,   Method: Compositional matrix adjust.
 Identities = 16/32 (50%), Positives = 17/32 (53%)
 Frame = -2

Query: 1025 CGSSSFPCNNGKCVPSIFRCDGVDDCHDNSDE 1056
            C S  F C  G C+P    CD V DC D SDE
Sbjct: 118  CTSEEFKCPAGPCIPLTHTCDSVHDCPDGSDE 23

 Score = 35.0 bits (79), Expect = 0.64,   Method: Compositional matrix adjust.
 Identities = 26/85 (30%), Positives = 37/85 (43%), Gaps = 12/85 (14%)
 Frame = -1

Query: 3629 PSHCASRTCRPGQFKC-NNGR--CIPQSWKCDVDNDCGDYSDEPIHECMTAAYNCD--NH 3683
            P  C    C   +F C  NG+  C+P++ +C++  DC D  DE    C   +Y CD  N 
Sbjct: 860  PGKCELHGCGDEEFSCYTNGKWNCLPRAXQCNIVIDCDDAEDEK--NCTAPSYKCDFENX 687

Query: 3684 TEFSCKTNYR-------CIPQWAVC 3701
              F   T ++        I QW  C
Sbjct: 686  VIFGXGTRFQGL*ERRMAIGQWLTC 612

 Score = 34.7 bits (78), Expect = 0.83,   Method: Compositional matrix adjust.
 Identities = 17/37 (45%), Positives = 22/37 (59%)
 Frame = -2

Query: 3514 CSSTQFLCGNNEKCIPIWWKCDGQKDCSDGSDESDLC 3550
            C+S +F C     CIP+   CD   DC DGSDE+ +C
Sbjct: 118  CTSEEFKCPAG-PCIPLTHTCDSVHDCPDGSDEASVC 11

 Score = 33.5 bits (75), Expect = 1.9,   Method: Compositional matrix adjust.
 Identities = 17/43 (39%), Positives = 23/43 (53%), Gaps = 3/43 (6%)
 Frame = -1

Query: 3795 CEMKTCHPEHFQCTSG---HCVPKALACDGRADCLDASDESAC 3834
            CE+  C  E F C +    +C+P+A  C+   DC DA DE  C
Sbjct: 851  CELHGCGDEEFSCYTNGKWNCLPRAXQCNIVIDCDDAEDEKNC 723

 Score = 33.5 bits (75), Expect = 2.0,   Method: Compositional matrix adjust.
 Identities = 28/95 (29%), Positives = 35/95 (36%)
 Frame = -2

Query: 2809 DNDTSDEKNCPPITCQPDFAKCQTTNICVPRAFLXXXXXXXXXXXXENPIYCASHTCRSN 2868
            DN T     CP  +C     KC+T   C+  +              E         C S 
Sbjct: 271  DNITITSGACPEFSCPSGKTKCKTEPYCLDDSRFCDRIKDCDEFADETDC-----NCTSE 107

Query: 2869 EFQCVSPHRCIPSYWFCDGEADCVDSSDEPDTCGH 2903
            EF+C +   CIP    CD   DC D SDE   C +
Sbjct: 106  EFKCPAG-PCIPLTHTCDSVHDCPDGSDEASVCDY 5

 Score = 33.5 bits (75), Expect = 2.0,   Method: Compositional matrix adjust.
 Identities = 18/47 (38%), Positives = 23/47 (48%), Gaps = 3/47 (6%)
 Frame = -1

Query: 2733 LPTVCAFHTCRSTAFTC-ANGR--CVPYHYRCDFYNDCGDNSDEAGC 2776
            LP  C  H C    F+C  NG+  C+P   +C+   DC D  DE  C
Sbjct: 863  LPGKCELHGCGDEEFSCYTNGKWNCLPRAXQCNIVIDCDDAEDEKNC 723

 Score = 33.1 bits (74), Expect = 2.9,   Method: Compositional matrix adjust.
 Identities = 17/48 (35%), Positives = 27/48 (56%), Gaps = 3/48 (6%)
 Frame = -1

Query: 102 NCPGTTCSSQQLTC-SNGQ--CVPIEYRCDHVSDCPDGSDERNCYYPT 146
            C    C  ++ +C +NG+  C+P   +C+ V DC D  DE+NC  P+
Sbjct: 854 KCELHGCGDEEFSCYTNGKWNCLPRAXQCNIVIDCDDAEDEKNCTAPS 711

 Score = 32.7 bits (73), Expect = 3.6,   Method: Compositional matrix adjust.
 Identities = 17/47 (36%), Positives = 26/47 (55%), Gaps = 3/47 (6%)
 Frame = -1

Query: 2989 NCTMRACSTGEFSC-ANGR--CIRQSFRCDRRNDCGDYSDERGCSYP 3032
             C +  C   EFSC  NG+  C+ ++ +C+   DC D  DE+ C+ P
Sbjct: 854  KCELHGCGDEEFSCYTNGKWNCLPRAXQCNIVIDCDDAEDEKNCTAP 714

 Score = 31.6 bits (70), Expect = 7.2,   Method: Compositional matrix adjust.
 Identities = 19/45 (42%), Positives = 23/45 (51%), Gaps = 3/45 (6%)
 Frame = -1

Query: 1025 CGSSSFPC-NNGK--CVPSIFRCDGVDDCHDNSDEHQCGALNNTC 1066
            CG   F C  NGK  C+P   +C+ V DC D  DE  C A +  C
Sbjct: 836  CGDEEFSCYTNGKWNCLPRAXQCNIVIDCDDAEDEKNCTAPSYKC 702

 Score = 31.2 bits (69), Expect = 9.8,   Method: Compositional matrix adjust.
 Identities = 16/36 (44%), Positives = 21/36 (58%), Gaps = 2/36 (5%)
 Frame = -1

Query: 3685 EFSCKTN--YRCIPQWAVCNGFDDCRDNSDEQGCES 3718
            EFSC TN  + C+P+   CN   DC D  DE+ C +
Sbjct: 824  EFSCYTNGKWNCLPRAXQCNIVIDCDDAEDEKNCTA 717
>14418
          Length = 1408

 Score = 66.2 bits (160), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 39/94 (41%), Positives = 53/94 (56%), Gaps = 4/94 (4%)
 Frame = -3

Query: 3593 HHRCEANEWQC---ANKRCIPEYWQCDSVDDCLDNSDEDPSHCASRT-CRPGQFKCNNGR 3648
            H RC  +E+QC    ++ CIP YW CD   DC  +  ED  +CA R+ C  G F+CN+G 
Sbjct: 1244 HARCADDEFQCHASPDRDCIPNYWVCDHSADC--DGGEDEINCAERSRCDEGDFRCNDGD 1071

Query: 3649 CIPQSWKCDVDNDCGDYSDEPIHECMTAAYNCDN 3682
            CIP  W CD D+DC +  DE    C   + + D+
Sbjct: 1070 CIPGDWLCDGDDDCQEGEDEDTTVCSAFSQDSDS 969

 Score = 66.2 bits (160), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 35/77 (45%), Positives = 42/77 (54%), Gaps = 2/77 (2%)
 Frame = -3

Query: 1229 GMCHPDEFQCQG--DGTCIPNTWECDGHPDCIQGSDEHNGCVPKTCSPSHFLCDNGNCIY 1286
              C  DEFQC    D  CIPN W CD   DC  G DE N      C    F C++G+CI 
Sbjct: 1241 ARCADDEFQCHASPDRDCIPNYWVCDHSADCDGGEDEINCAERSRCDEGDFRCNDGDCIP 1062

Query: 1287 NSWVCDGDNDCRDMSDE 1303
              W+CDGD+DC++  DE
Sbjct: 1061 GDWLCDGDDDCQEGEDE 1011

 Score = 64.3 bits (155), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 37/78 (47%), Positives = 45/78 (57%), Gaps = 2/78 (2%)
 Frame = -3

Query: 2865 CRSNEFQC-VSPHR-CIPSYWFCDGEADCVDSSDEPDTCGHSLNSCSANQFHCDNGRCIS 2922
            C  +EFQC  SP R CIP+YW CD  ADC    DE +    S   C    F C++G CI 
Sbjct: 1235 CADDEFQCHASPDRDCIPNYWVCDHSADCDGGEDEINCAERSR--CDEGDFRCNDGDCIP 1062

Query: 2923 SSWVCDGDNDCGDMSDED 2940
              W+CDGD+DC +  DED
Sbjct: 1061 GDWLCDGDDDCQEGEDED 1008

 Score = 59.7 bits (143), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 30/60 (50%), Positives = 33/60 (55%)
 Frame = -3

Query: 1122 CIPKEWVCDTDNDCSDGSDEKNCQASGTCHPTQFRCPDHRCISPLYVCDGDKDCVDGSDE 1181
            CIP  WVCD   DC  G DE NC     C    FRC D  CI   ++CDGD DC +G DE
Sbjct: 1190 CIPNYWVCDHSADCDGGEDEINCAERSRCDEGDFRCNDGDCIPGDWLCDGDDDCQEGEDE 1011

 Score = 58.9 bits (141), Expect = 5e-08,   Method: Compositional matrix adjust.
 Identities = 31/87 (35%), Positives = 42/87 (48%), Gaps = 2/87 (2%)
 Frame = -3

Query: 3507 RTLCMPMCSSTQFLC--GNNEKCIPIWWKCDGQKDCSDGSDESDLCPHRFCRLGQFQCRD 3564
            R+     C+  +F C    +  CIP +W CD   DC  G DE +      C  G F+C D
Sbjct: 1256 RSTYHARCADDEFQCHASPDRDCIPNYWVCDHSADCDGGEDEINCAERSRCDEGDFRCND 1077

Query: 3565 GNCTSPQALCNARQDCADGSDEDRVLC 3591
            G+C     LC+   DC +G DED  +C
Sbjct: 1076 GDCIPGDWLCDGDDDCQEGEDEDTTVC 996

 Score = 57.0 bits (136), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 34/76 (44%), Positives = 40/76 (52%), Gaps = 4/76 (5%)
 Frame = -3

Query: 28   CGSGNFRCD---NGYCIPASWRCDGTRDCLDDTDEIGCPPRS-CGSGFFLCPAEGTCIPS 83
            C    F+C    +  CIP  W CD + DC    DEI C  RS C  G F C  +G CIP 
Sbjct: 1235 CADDEFQCHASPDRDCIPNYWVCDHSADCDGGEDEINCAERSRCDEGDFRC-NDGDCIPG 1059

Query: 84   SWVCDQDKDCSDGADE 99
             W+CD D DC +G DE
Sbjct: 1058 DWLCDGDDDCQEGEDE 1011

 Score = 55.5 bits (132), Expect = 5e-07,   Method: Compositional matrix adjust.
 Identities = 31/75 (41%), Positives = 39/75 (52%), Gaps = 4/75 (5%)
 Frame = -3

Query: 3761 CTESEFRC---ADQQCIPSRWVCDQENDCGDNSDERDC-EMKTCHPEHFQCTSGHCVPKA 3816
            C + EF+C    D+ CIP+ WVCD   DC    DE +C E   C    F+C  G C+P  
Sbjct: 1235 CADDEFQCHASPDRDCIPNYWVCDHSADCDGGEDEINCAERSRCDEGDFRCNDGDCIPGD 1056

Query: 3817 LACDGRADCLDASDE 3831
              CDG  DC +  DE
Sbjct: 1055 WLCDGDDDCQEGEDE 1011

 Score = 54.3 bits (129), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 28/60 (46%), Positives = 34/60 (56%), Gaps = 1/60 (1%)
 Frame = -3

Query: 3734 CIPLRWKCDGIDDCGDNSDEESCVPR-ECTESEFRCADQQCIPSRWVCDQENDCGDNSDE 3792
            CIP  W CD   DC    DE +C  R  C E +FRC D  CIP  W+CD ++DC +  DE
Sbjct: 1190 CIPNYWVCDHSADCDGGEDEINCAERSRCDEGDFRCNDGDCIPGDWLCDGDDDCQEGEDE 1011

 Score = 53.1 bits (126), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 30/84 (35%), Positives = 41/84 (48%), Gaps = 3/84 (3%)
 Frame = -3

Query: 3800 CHPEHFQCTSG---HCVPKALACDGRADCLDASDESACPTRFPNGTYCPAAMFECKNHVC 3856
            C  + FQC +     C+P    CD  ADC    DE  C  R    + C    F C +  C
Sbjct: 1235 CADDEFQCHASPDRDCIPNYWVCDHSADCDGGEDEINCAER----SRCDEGDFRCNDGDC 1068

Query: 3857 IQSFWICDGENDCVDGSDEEIHLC 3880
            I   W+CDG++DC +G DE+  +C
Sbjct: 1067 IPGDWLCDGDDDCQEGEDEDTTVC 996

 Score = 52.0 bits (123), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 31/75 (41%), Positives = 38/75 (50%), Gaps = 2/75 (2%)
 Frame = -3

Query: 3685 EFSCKT--NYRCIPQWAVCNGFDDCRDNSDEQGCESVPCHPSGDFRCGNHHCIPLRWKCD 3742
            EF C    +  CIP + VC+   DC    DE  C        GDFRC +  CIP  W CD
Sbjct: 1223 EFQCHASPDRDCIPNYWVCDHSADCDGGEDEINCAERSRCDEGDFRCNDGDCIPGDWLCD 1044

Query: 3743 GIDDCGDNSDEESCV 3757
            G DDC +  DE++ V
Sbjct: 1043 GDDDCQEGEDEDTTV 999

 Score = 52.0 bits (123), Expect = 6e-06,   Method: Compositional matrix adjust.
 Identities = 28/75 (37%), Positives = 37/75 (49%), Gaps = 2/75 (2%)
 Frame = -3

Query: 67   CGSGFFLCPA--EGTCIPSSWVCDQDKDCSDGADEQQNCPGTTCSSQQLTCSNGQCVPIE 124
            C    F C A  +  CIP+ WVCD   DC  G DE      + C      C++G C+P +
Sbjct: 1235 CADDEFQCHASPDRDCIPNYWVCDHSADCDGGEDEINCAERSRCDEGDFRCNDGDCIPGD 1056

Query: 125  YRCDHVSDCPDGSDE 139
            + CD   DC +G DE
Sbjct: 1055 WLCDGDDDCQEGEDE 1011

 Score = 50.4 bits (119), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 32/85 (37%), Positives = 45/85 (52%), Gaps = 3/85 (3%)
 Frame = -3

Query: 3836 TRFPNGTYCPAAMFECK---NHVCIQSFWICDGENDCVDGSDEEIHLCFNVPCESPQRFR 3892
            TR      C    F+C    +  CI ++W+CD   DC DG ++EI+      C+    FR
Sbjct: 1259 TRSTYHARCADDEFQCHASPDRDCIPNYWVCDHSADC-DGGEDEINCAERSRCDEGD-FR 1086

Query: 3893 CDNSRCIYGHQLCNGVDDCGDGSDE 3917
            C++  CI G  LC+G DDC +G DE
Sbjct: 1085 CNDGDCIPGDWLCDGDDDCQEGEDE 1011

 Score = 47.4 bits (111), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 30/78 (38%), Positives = 38/78 (48%), Gaps = 2/78 (2%)
 Frame = -3

Query: 1188 CTSSQFKC--ADGSSCINSRYRCDGVYDCKDNSDEAGCPTRPPGMCHPDEFQCQGDGTCI 1245
            C   +F+C  +    CI + + CD   DC    DE  C  R    C   +F+C  DG CI
Sbjct: 1235 CADDEFQCHASPDRDCIPNYWVCDHSADCDGGEDEINCAER--SRCDEGDFRCN-DGDCI 1065

Query: 1246 PNTWECDGHPDCIQGSDE 1263
            P  W CDG  DC +G DE
Sbjct: 1064 PGDWLCDGDDDCQEGEDE 1011

 Score = 47.4 bits (111), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 29/78 (37%), Positives = 39/78 (50%), Gaps = 3/78 (3%)
 Frame = -3

Query: 1024 QCGSSSFPCN---NGKCVPSIFRCDGVDDCHDNSDEHQCGALNNTCSSSAFTCVHGGQCI 1080
            +C    F C+   +  C+P+ + CD   DC    DE  C A  + C    F C + G CI
Sbjct: 1238 RCADDEFQCHASPDRDCIPNYWVCDHSADCDGGEDEINC-AERSRCDEGDFRC-NDGDCI 1065

Query: 1081 PGQWRCDKQNDCLDGSDE 1098
            PG W CD  +DC +G DE
Sbjct: 1064 PGDWLCDGDDDCQEGEDE 1011

 Score = 47.0 bits (110), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 27/94 (28%), Positives = 44/94 (46%), Gaps = 4/94 (4%)
 Frame = -3

Query: 2733 LPTVCAFHT-CRSTAFTC---ANGRCVPYHYRCDFYNDCGDNSDEAGCLFRSCNSTTEFT 2788
            + T   +H  C    F C    +  C+P ++ CD   DC    DE  C  RS     +F 
Sbjct: 1265 VSTRSTYHARCADDEFQCHASPDRDCIPNYWVCDHSADCDGGEDEINCAERSRCDEGDFR 1086

Query: 2789 CSNGRCIPLSYVCNGINNCHDNDTSDEKNCPPIT 2822
            C++G CIP  ++C+G ++C + +  D   C   +
Sbjct: 1085 CNDGDCIPGDWLCDGDDDCQEGEDEDTTVCSAFS 984

 Score = 46.2 bits (108), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 31/87 (35%), Positives = 45/87 (51%), Gaps = 4/87 (4%)
 Frame = -3

Query: 3552 HRFCRLGQFQCR---DGNCTSPQALCNARQDCADGSDEDRVLC-EHHRCEANEWQCANKR 3607
            H  C   +FQC    D +C     +C+   DC  G DE  + C E  RC+  +++C +  
Sbjct: 1244 HARCADDEFQCHASPDRDCIPNYWVCDHSADCDGGEDE--INCAERSRCDEGDFRCNDGD 1071

Query: 3608 CIPEYWQCDSVDDCLDNSDEDPSHCAS 3634
            CIP  W CD  DDC +  DED + C++
Sbjct: 1070 CIPGDWLCDGDDDCQEGEDEDTTVCSA 990

 Score = 45.8 bits (107), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 30/76 (39%), Positives = 37/76 (48%), Gaps = 5/76 (6%)
 Frame = -3

Query: 1150 CHPTQFRC---PDHRCISPLYVCDGDKDCVDGSDEAGCV--LNCTSSQFKCADGSSCINS 1204
            C   +F+C   PD  CI   +VCD   DC  G DE  C     C    F+C DG  CI  
Sbjct: 1235 CADDEFQCHASPDRDCIPNYWVCDHSADCDGGEDEINCAERSRCDEGDFRCNDG-DCIPG 1059

Query: 1205 RYRCDGVYDCKDNSDE 1220
             + CDG  DC++  DE
Sbjct: 1058 DWLCDGDDDCQEGEDE 1011

 Score = 45.8 bits (107), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 22/53 (41%), Positives = 32/53 (60%), Gaps = 2/53 (3%)
 Frame = -3

Query: 164  CDHKVDCRDSSDEANCT--TLCSQKEFQCGSGECILRAYVCDHDNDCEDNSDE 214
            CDH  DC    DE NC   + C + +F+C  G+CI   ++CD D+DC++  DE
Sbjct: 1169 CDHSADCDGGEDEINCAERSRCDEGDFRCNDGDCIPGDWLCDGDDDCQEGEDE 1011

 Score = 45.1 bits (105), Expect = 6e-04,   Method: Compositional matrix adjust.
 Identities = 29/78 (37%), Positives = 39/78 (50%), Gaps = 1/78 (1%)
 Frame = -3

Query: 2950 CSSTEFTCINSRPPNRRCIPQHWVXXXXXXXXXXXXELQNCTMRA-CSTGEFSCANGRCI 3008
            C+  EF C  S  P+R CIP +WV            E+ NC  R+ C  G+F C +G CI
Sbjct: 1235 CADDEFQCHAS--PDRDCIPNYWVCDHSADCDGGEDEI-NCAERSRCDEGDFRCNDGDCI 1065

Query: 3009 RQSFRCDRRNDCGDYSDE 3026
               + CD  +DC +  DE
Sbjct: 1064 PGDWLCDGDDDCQEGEDE 1011

 Score = 43.1 bits (100), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 29/79 (36%), Positives = 34/79 (43%), Gaps = 3/79 (3%)
 Frame = -3

Query: 1066 CSSSAFTCVHGG---QCIPGQWRCDKQNDCLDGSDEQNXXXXXXXXXXXXXXXXXDNHMC 1122
            C+   F C H      CIP  W CD   DC  G DE N                 D   C
Sbjct: 1235 CADDEFQC-HASPDRDCIPNYWVCDHSADCDGGEDEINCAERSRCDEGDFRCNDGD---C 1068

Query: 1123 IPKEWVCDTDNDCSDGSDE 1141
            IP +W+CD D+DC +G DE
Sbjct: 1067 IPGDWLCDGDDDCQEGEDE 1011

 Score = 42.4 bits (98), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 29/85 (34%), Positives = 39/85 (45%), Gaps = 3/85 (3%)
 Frame = -3

Query: 3027 RGCSYPPCRDDQFTCQ---NGQCITKLYVCDEDNDCGDGSDEQEHLCHTPEPTCPPHQFR 3083
            R   +  C DD+F C    +  CI   +VCD   DC  G DE   +       C    FR
Sbjct: 1256 RSTYHARCADDEFQCHASPDRDCIPNYWVCDHSADCDGGEDE---INCAERSRCDEGDFR 1086

Query: 3084 CDNGHCIEMGTVCNHVDDCSDNSDE 3108
            C++G CI    +C+  DDC +  DE
Sbjct: 1085 CNDGDCIPGDWLCDGDDDCQEGEDE 1011

 Score = 41.6 bits (96), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 28/80 (35%), Positives = 39/80 (48%), Gaps = 4/80 (5%)
 Frame = -3

Query: 2995 CSTGEFSC---ANGRCIRQSFRCDRRNDCGDYSDERGCS-YPPCRDDQFTCQNGQCITKL 3050
            C+  EF C    +  CI   + CD   DC    DE  C+    C +  F C +G CI   
Sbjct: 1235 CADDEFQCHASPDRDCIPNYWVCDHSADCDGGEDEINCAERSRCDEGDFRCNDGDCIPGD 1056

Query: 3051 YVCDEDNDCGDGSDEQEHLC 3070
            ++CD D+DC +G DE   +C
Sbjct: 1055 WLCDGDDDCQEGEDEDTTVC 996

 Score = 41.6 bits (96), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 24/64 (37%), Positives = 33/64 (51%), Gaps = 4/64 (6%)
 Frame = -3

Query: 181  TLCSQKEFQCGSG---ECILRAYVCDHDNDCEDNSDEHNC-NYDTCGGHQFTCSNGQCIN 236
              C+  EFQC +    +CI   +VCDH  DC+   DE NC     C    F C++G CI 
Sbjct: 1241 ARCADDEFQCHASPDRDCIPNYWVCDHSADCDGGEDEINCAERSRCDEGDFRCNDGDCIP 1062

Query: 237  QNWV 240
             +W+
Sbjct: 1061 GDWL 1050

 Score = 38.9 bits (89), Expect = 0.048,   Method: Compositional matrix adjust.
 Identities = 29/83 (34%), Positives = 41/83 (49%), Gaps = 6/83 (7%)
 Frame = -3

Query: 108  CSSQQLTCS---NGQCVPIEYRCDHVSDCPDGSDERNCYYPT-CDQ--LTCANGACYNTS 161
            C+  +  C    +  C+P  + CDH +DC  G DE NC   + CD+    C +G C    
Sbjct: 1235 CADDEFQCHASPDRDCIPNYWVCDHSADCDGGEDEINCAERSRCDEGDFRCNDGDCIPGD 1056

Query: 162  QKCDHKVDCRDSSDEANCTTLCS 184
              CD   DC++  DE   TT+CS
Sbjct: 1055 WLCDGDDDCQEGEDED--TTVCS 993

 Score = 35.8 bits (81), Expect = 0.36,   Method: Compositional matrix adjust.
 Identities = 27/77 (35%), Positives = 35/77 (45%), Gaps = 3/77 (3%)
 Frame = -3

Query: 1272 CSPSHFLCD---NGNCIYNSWVCDGDNDCRDMSDEKDCPTQPFHCPSSQWQCPGYSICVN 1328
            C+   F C    + +CI N WVCD   DC    DE +C  +   C    ++C     C+ 
Sbjct: 1235 CADDEFQCHASPDRDCIPNYWVCDHSADCDGGEDEINCAERS-RCDEGDFRC-NDGDCIP 1062

Query: 1329 LSALCDGVFDCPNGTDE 1345
               LCDG  DC  G DE
Sbjct: 1061 GDWLCDGDDDCQEGEDE 1011

 Score = 33.9 bits (76), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 19/47 (40%), Positives = 26/47 (55%), Gaps = 1/47 (2%)
 Frame = -3

Query: 2855 ENPIYCASHT-CRSNEFQCVSPHRCIPSYWFCDGEADCVDSSDEPDT 2900
            E+ I CA  + C   +F+C +   CIP  W CDG+ DC +  DE  T
Sbjct: 1139 EDEINCAERSRCDEGDFRC-NDGDCIPGDWLCDGDDDCQEGEDEDTT 1002

 Score = 33.9 bits (76), Expect = 1.7,   Method: Compositional matrix adjust.
 Identities = 20/64 (31%), Positives = 37/64 (57%)
 Frame = -3

Query: 3898 CIYGHQLCNGVDDCGDGSDEKEEHCRKPTHKPCTDTEYKCSNGNCVSQHYVCDNVDDCGD 3957
            CI  + +C+   DC  G DE   +C + +   C + +++C++G+C+   ++CD  DDC +
Sbjct: 1190 CIPNYWVCDHSADCDGGEDEI--NCAERSR--CDEGDFRCNDGDCIPGDWLCDGDDDCQE 1023

Query: 3958 LSDE 3961
              DE
Sbjct: 1022 GEDE 1011
>36074
          Length = 478

 Score = 43.9 bits (102), Expect(2) = 3e-10,   Method: Compositional matrix adjust.
 Identities = 26/63 (41%), Positives = 35/63 (55%), Gaps = 1/63 (1%)
 Frame = +1

Query: 158 YNTSQKCDHKVDCRDSSDEANCTTLCSQKEFQCGS-GECILRAYVCDHDNDCEDNSDEHN 216
           +NTS   + + +CRD  DE NC +   + EFQC S G CI   Y C+   +C D SDE +
Sbjct: 184 HNTSG--NGRAECRDGRDEQNCPSCDEETEFQCVSDGRCIPIIYRCNGRPECTDRSDEDS 357

Query: 217 CNY 219
           C  
Sbjct: 358 CQL 366

 Score = 42.0 bits (97), Expect(2) = 3e-10,   Method: Compositional matrix adjust.
 Identities = 24/59 (40%), Positives = 33/59 (55%)
 Frame = +3

Query: 67  CGSGFFLCPAEGTCIPSSWVCDQDKDCSDGADEQQNCPGTTCSSQQLTCSNGQCVPIEY 125
           C    F C     CIP+S  CD+  DC DG+DE+    G  CS  +L C +G+C+P +Y
Sbjct: 24  CREDEFTCETSRDCIPASRRCDRRSDCDDGSDERDC--GPVCSEGELEC-DGRCLPPQY 191

 Score = 47.8 bits (112), Expect(2) = 6e-10,   Method: Compositional matrix adjust.
 Identities = 24/56 (42%), Positives = 32/56 (57%), Gaps = 1/56 (1%)
 Frame = +1

Query: 1209 DGVYDCKDNSDEAGCPTRPPGMCHPD-EFQCQGDGTCIPNTWECDGHPDCIQGSDE 1263
            +G  +C+D  DE  CP+     C  + EFQC  DG CIP  + C+G P+C   SDE
Sbjct: 199  NGRAECRDGRDEQNCPS-----CDEETEFQCVSDGRCIPIIYRCNGRPECTDRSDE 351

 Score = 37.4 bits (85), Expect(2) = 6e-10,   Method: Compositional matrix adjust.
 Identities = 20/47 (42%), Positives = 26/47 (55%)
 Frame = +3

Query: 1122 CIPKEWVCDTDNDCSDGSDEKNCQASGTCHPTQFRCPDHRCISPLYV 1168
            CIP    CD  +DC DGSDE++C     C   +  C D RC+ P Y+
Sbjct: 63   CIPASRRCDRRSDCDDGSDERDCGP--VCSEGELEC-DGRCLPPQYI 194

 Score = 45.8 bits (107), Expect(2) = 2e-09,   Method: Compositional matrix adjust.
 Identities = 25/60 (41%), Positives = 32/60 (53%)
 Frame = +3

Query: 3514 CSSTQFLCGNNEKCIPIWWKCDGQKDCSDGSDESDLCPHRFCRLGQFQCRDGNCTSPQAL 3573
            C   +F C  +  CIP   +CD + DC DGSDE D  P   C  G+ +C DG C  PQ +
Sbjct: 24   CREDEFTCETSRDCIPASRRCDRRSDCDDGSDERDCGP--VCSEGELEC-DGRCLPPQYI 194

 Score = 37.4 bits (85), Expect(2) = 2e-09,   Method: Compositional matrix adjust.
 Identities = 23/56 (41%), Positives = 32/56 (57%), Gaps = 2/56 (3%)
 Frame = +1

Query: 3575 NARQDCADGSDEDRV-LCEHHRCEANEWQC-ANKRCIPEYWQCDSVDDCLDNSDED 3628
            N R +C DG DE     C+    E  E+QC ++ RCIP  ++C+   +C D SDED
Sbjct: 199  NGRAECRDGRDEQNCPSCD----EETEFQCVSDGRCIPIIYRCNGRPECTDRSDED 354

 Score = 43.1 bits (100), Expect(2) = 2e-09,   Method: Compositional matrix adjust.
 Identities = 24/54 (44%), Positives = 32/54 (59%), Gaps = 1/54 (1%)
 Frame = +1

Query: 1134 DCSDGSDEKNCQASGTCHPTQFRC-PDHRCISPLYVCDGDKDCVDGSDEAGCVL 1186
            +C DG DE+NC +      T+F+C  D RCI  +Y C+G  +C D SDE  C L
Sbjct: 211  ECRDGRDEQNCPSCD--EETEFQCVSDGRCIPIIYRCNGRPECTDRSDEDSCQL 366

 Score = 40.0 bits (92), Expect(2) = 2e-09,   Method: Compositional matrix adjust.
 Identities = 18/38 (47%), Positives = 23/38 (60%)
 Frame = +3

Query: 1063 NNTCSSSAFTCVHGGQCIPGQWRCDKQNDCLDGSDEQN 1100
            N  C    FTC     CIP   RCD+++DC DGSDE++
Sbjct: 15   NCPCREDEFTCETSRDCIPASRRCDRRSDCDDGSDERD 128

 Score = 48.9 bits (115), Expect(2) = 9e-09,   Method: Compositional matrix adjust.
 Identities = 26/59 (44%), Positives = 36/59 (61%), Gaps = 1/59 (1%)
 Frame = +1

Query: 3702 NGFDDCRDNSDEQGCESVPCHPSGDFRC-GNHHCIPLRWKCDGIDDCGDNSDEESCVPR 3759
            NG  +CRD  DEQ C S  C    +F+C  +  CIP+ ++C+G  +C D SDE+SC  R
Sbjct: 199  NGRAECRDGRDEQNCPS--CDEETEFQCVSDGRCIPIIYRCNGRPECTDRSDEDSCQLR 369

 Score = 32.0 bits (71), Expect(2) = 9e-09,   Method: Compositional matrix adjust.
 Identities = 17/33 (51%), Positives = 20/33 (60%), Gaps = 1/33 (3%)
 Frame = +3

Query: 3637 CRPGQFKCNNGR-CIPQSWKCDVDNDCGDYSDE 3668
            CR  +F C   R CIP S +CD  +DC D SDE
Sbjct: 24   CREDEFTCETSRDCIPASRRCDRRSDCDDGSDE 122

 Score = 43.5 bits (101), Expect(2) = 1e-08,   Method: Compositional matrix adjust.
 Identities = 23/53 (43%), Positives = 32/53 (60%)
 Frame = +1

Query: 92  DCSDGADEQQNCPGTTCSSQQLTCSNGQCVPIEYRCDHVSDCPDGSDERNCYY 144
           +C DG DEQ NCP     ++    S+G+C+PI YRC+   +C D SDE +C  
Sbjct: 211 ECRDGRDEQ-NCPSCDEETEFQCVSDGRCIPIIYRCNGRPECTDRSDEDSCQL 366

 Score = 36.6 bits (83), Expect(2) = 1e-08,   Method: Compositional matrix adjust.
 Identities = 24/60 (40%), Positives = 30/60 (50%), Gaps = 1/60 (1%)
 Frame = +3

Query: 28 CGSGNFRCDNGY-CIPASWRCDGTRDCLDDTDEIGCPPRSCGSGFFLCPAEGTCIPSSWV 86
          C    F C+    CIPAS RCD   DC D +DE  C P  C  G   C  +G C+P  ++
Sbjct: 24 CREDEFTCETSRDCIPASRRCDRRSDCDDGSDERDCGP-VCSEGELEC--DGRCLPPQYI 194

 Score = 42.4 bits (98), Expect(2) = 4e-08,   Method: Compositional matrix adjust.
 Identities = 24/56 (42%), Positives = 32/56 (57%), Gaps = 2/56 (3%)
 Frame = +1

Query: 3785 DCGDNSDERDCEMKTCHPE-HFQCTS-GHCVPKALACDGRADCLDASDESACPTRF 3838
            +C D  DE++C   +C  E  FQC S G C+P    C+GR +C D SDE +C  R 
Sbjct: 211  ECRDGRDEQNC--PSCDEETEFQCVSDGRCIPIIYRCNGRPECTDRSDEDSCQLRI 372

 Score = 36.6 bits (83), Expect(2) = 4e-08,   Method: Compositional matrix adjust.
 Identities = 20/49 (40%), Positives = 28/49 (57%)
 Frame = +3

Query: 3731 NHHCIPLRWKCDGIDDCGDNSDEESCVPRECTESEFRCADQQCIPSRWV 3779
            +  CIP   +CD   DC D SDE  C P  C+E E  C D +C+P +++
Sbjct: 54   SRDCIPASRRCDRRSDCDDGSDERDCGP-VCSEGELEC-DGRCLPPQYI 194

 Score = 42.4 bits (98), Expect(2) = 1e-07,   Method: Compositional matrix adjust.
 Identities = 19/39 (48%), Positives = 24/39 (61%)
 Frame = +1

Query: 3679 NCDNHTEFSCKTNYRCIPQWAVCNGFDDCRDNSDEQGCE 3717
            +CD  TEF C ++ RCIP    CNG  +C D SDE  C+
Sbjct: 247  SCDEETEFQCVSDGRCIPIIYRCNGRPECTDRSDEDSCQ 363

 Score = 34.3 bits (77), Expect(2) = 1e-07,   Method: Compositional matrix adjust.
 Identities = 23/60 (38%), Positives = 31/60 (51%), Gaps = 1/60 (1%)
 Frame = +3

Query: 3596 CEANEWQCANKR-CIPEYWQCDSVDDCLDNSDEDPSHCASRTCRPGQFKCNNGRCIPQSW 3654
            C  +E+ C   R CIP   +CD   DC D SDE    C    C  G+ +C +GRC+P  +
Sbjct: 24   CREDEFTCETSRDCIPASRRCDRRSDCDDGSDE--RDCGP-VCSEGELEC-DGRCLPPQY 191

 Score = 43.5 bits (101), Expect(2) = 7e-07,   Method: Compositional matrix adjust.
 Identities = 27/59 (45%), Positives = 35/59 (59%), Gaps = 1/59 (1%)
 Frame = +3

Query: 2995 CSTGEFSCANGR-CIRQSFRCDRRNDCGDYSDERGCSYPPCRDDQFTCQNGQCITKLYV 3052
            C   EF+C   R CI  S RCDRR+DC D SDER C  P C + +  C +G+C+   Y+
Sbjct: 24   CREDEFTCETSRDCIPASRRCDRRSDCDDGSDERDCG-PVCSEGELEC-DGRCLPPQYI 194

 Score = 30.8 bits (68), Expect(2) = 7e-07,   Method: Compositional matrix adjust.
 Identities = 21/58 (36%), Positives = 30/58 (51%), Gaps = 2/58 (3%)
 Frame = +1

Query: 3058 DCGDGSDEQEHLCHTPEPTCPPH-QFRC-DNGHCIEMGTVCNHVDDCSDNSDEKGCGI 3113
            +C DG DEQ        P+C    +F+C  +G CI +   CN   +C+D SDE  C +
Sbjct: 211  ECRDGRDEQNC------PSCDEETEFQCVSDGRCIPIIYRCNGRPECTDRSDEDSCQL 366

 Score = 38.5 bits (88), Expect(2) = 4e-06,   Method: Compositional matrix adjust.
 Identities = 22/58 (37%), Positives = 36/58 (62%), Gaps = 1/58 (1%)
 Frame = +1

Query: 3742 DGIDDCGDNSDEESCVPRECTESEFRC-ADQQCIPSRWVCDQENDCGDNSDERDCEMK 3798
            +G  +C D  DE++C P    E+EF+C +D +CIP  + C+   +C D SDE  C+++
Sbjct: 199  NGRAECRDGRDEQNC-PSCDEETEFQCVSDGRCIPIIYRCNGRPECTDRSDEDSCQLR 369

 Score = 33.1 bits (74), Expect(2) = 4e-06,   Method: Compositional matrix adjust.
 Identities = 20/57 (35%), Positives = 30/57 (52%)
 Frame = +3

Query: 3683 HTEFSCKTNYRCIPQWAVCNGFDDCRDNSDEQGCESVPCHPSGDFRCGNHHCIPLRW 3739
              EF+C+T+  CIP    C+   DC D SDE+ C  V     G+  C +  C+P ++
Sbjct: 30   EDEFTCETSRDCIPASRRCDRRSDCDDGSDERDCGPV--CSEGELEC-DGRCLPPQY 191

 Score = 38.5 bits (88), Expect(2) = 6e-06,   Method: Compositional matrix adjust.
 Identities = 24/55 (43%), Positives = 30/55 (54%), Gaps = 1/55 (1%)
 Frame = +3

Query: 3761 CTESEFRC-ADQQCIPSRWVCDQENDCGDNSDERDCEMKTCHPEHFQCTSGHCVP 3814
            C E EF C   + CIP+   CD+ +DC D SDERDC    C     +C  G C+P
Sbjct: 24   CREDEFTCETSRDCIPASRRCDRRSDCDDGSDERDC-GPVCSEGELEC-DGRCLP 182

 Score = 32.7 bits (73), Expect(2) = 6e-06,   Method: Compositional matrix adjust.
 Identities = 22/65 (33%), Positives = 32/65 (49%), Gaps = 2/65 (3%)
 Frame = +1

Query: 3814 PKALACDGRADCLDASDESACPTRFPNGTYC-PAAMFEC-KNHVCIQSFWICDGENDCVD 3871
            P   + +GRA+C D  DE  CP+       C     F+C  +  CI   + C+G  +C D
Sbjct: 181  PHNTSGNGRAECRDGRDEQNCPS-------CDEETEFQCVSDGRCIPIIYRCNGRPECTD 339

Query: 3872 GSDEE 3876
             SDE+
Sbjct: 340  RSDED 354

 Score = 39.7 bits (91), Expect(2) = 2e-05,   Method: Compositional matrix adjust.
 Identities = 24/60 (40%), Positives = 30/60 (50%)
 Frame = +3

Query: 1231 CHPDEFQCQGDGTCIPNTWECDGHPDCIQGSDEHNGCVPKTCSPSHFLCDNGNCIYNSWV 1290
            C  DEF C+    CIP +  CD   DC  GSDE + C P  CS     CD G C+   ++
Sbjct: 24   CREDEFTCETSRDCIPASRRCDRRSDCDDGSDERD-CGP-VCSEGELECD-GRCLPPQYI 194

 Score = 30.0 bits (66), Expect(2) = 2e-05,   Method: Compositional matrix adjust.
 Identities = 16/54 (29%), Positives = 30/54 (55%)
 Frame = +1

Query: 1292 DGDNDCRDMSDEKDCPTQPFHCPSSQWQCPGYSICVNLSALCDGVFDCPNGTDE 1345
            +G  +CRD  DE++CP+       +++QC     C+ +   C+G  +C + +DE
Sbjct: 199  NGRAECRDGRDEQNCPSCDEE---TEFQCVSDGRCIPIIYRCNGRPECTDRSDE 351

 Score = 34.7 bits (78), Expect(2) = 6e-05,   Method: Compositional matrix adjust.
 Identities = 22/62 (35%), Positives = 28/62 (45%)
 Frame = +3

Query: 1188 CTSSQFKCADGSSCINSRYRCDGVYDCKDNSDEAGCPTRPPGMCHPDEFQCQGDGTCIPN 1247
            C   +F C     CI +  RCD   DC D SDE  C      +C   E +C  DG C+P 
Sbjct: 24   CREDEFTCETSRDCIPASRRCDRRSDCDDGSDERDCGP----VCSEGELEC--DGRCLPP 185

Query: 1248 TW 1249
             +
Sbjct: 186  QY 191

 Score = 33.1 bits (74), Expect(2) = 6e-05,   Method: Compositional matrix adjust.
 Identities = 21/62 (33%), Positives = 29/62 (46%), Gaps = 1/62 (1%)
 Frame = +1

Query: 1246 PNTWECDGHPDCIQGSDEHNGCVPKTCSPSHFLC-DNGNCIYNSWVCDGDNDCRDMSDEK 1304
            P+    +G  +C  G DE N   P     + F C  +G CI   + C+G  +C D SDE 
Sbjct: 181  PHNTSGNGRAECRDGRDEQN--CPSCDEETEFQCVSDGRCIPIIYRCNGRPECTDRSDED 354

Query: 1305 DC 1306
             C
Sbjct: 355  SC 360

 Score = 39.3 bits (90), Expect(2) = 1e-04,   Method: Compositional matrix adjust.
 Identities = 23/61 (37%), Positives = 30/61 (49%), Gaps = 1/61 (1%)
 Frame = +3

Query: 1025 CGSSSFPCNNGK-CVPSIFRCDGVDDCHDNSDEHQCGALNNTCSSSAFTCVHGGQCIPGQ 1083
            C    F C   + C+P+  RCD   DC D SDE  CG +   CS     C   G+C+P Q
Sbjct: 24   CREDEFTCETSRDCIPASRRCDRRSDCDDGSDERDCGPV---CSEGELEC--DGRCLPPQ 188

Query: 1084 W 1084
            +
Sbjct: 189  Y 191

 Score = 27.7 bits (60), Expect(2) = 1e-04,   Method: Compositional matrix adjust.
 Identities = 18/57 (31%), Positives = 26/57 (45%)
 Frame = +1

Query: 1089 QNDCLDGSDEQNXXXXXXXXXXXXXXXXXDNHMCIPKEWVCDTDNDCSDGSDEKNCQ 1145
            + +C DG DEQN                  +  CIP  + C+   +C+D SDE +CQ
Sbjct: 205  RAECRDGRDEQNCPSCDEETEFQCV----SDGRCIPIIYRCNGRPECTDRSDEDSCQ 363

 Score = 35.0 bits (79), Expect(2) = 3e-04,   Method: Compositional matrix adjust.
 Identities = 23/64 (35%), Positives = 29/64 (45%), Gaps = 1/64 (1%)
 Frame = +3

Query: 3800 CHPEHFQC-TSGHCVPKALACDGRADCLDASDESACPTRFPNGTYCPAAMFECKNHVCIQ 3858
            C  + F C TS  C+P +  CD R+DC D SDE  C      G  C     EC    C+ 
Sbjct: 24   CREDEFTCETSRDCIPASRRCDRRSDCDDGSDERDC------GPVCSEGELECDGR-CLP 182

Query: 3859 SFWI 3862
              +I
Sbjct: 183  PQYI 194

 Score = 30.8 bits (68), Expect(2) = 3e-04,   Method: Compositional matrix adjust.
 Identities = 22/56 (39%), Positives = 29/56 (51%), Gaps = 2/56 (3%)
 Frame = +1

Query: 3864 DGENDCVDGSDEEIHLCFNVP-CESPQRFRC-DNSRCIYGHQLCNGVDDCGDGSDE 3917
            +G  +C DG DE+     N P C+    F+C  + RCI     CNG  +C D SDE
Sbjct: 199  NGRAECRDGRDEQ-----NCPSCDEETEFQCVSDGRCIPIIYRCNGRPECTDRSDE 351

 Score = 45.4 bits (106), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 28/64 (43%), Positives = 36/64 (56%), Gaps = 1/64 (1%)
 Frame = +1

Query: 2756 PYHYRCDFYNDCGDNSDEAGCLFRSCNSTTEFTC-SNGRCIPLSYVCNGINNCHDNDTSD 2814
            P++   +   +C D  DE  C   SC+  TEF C S+GRCIP+ Y CNG   C D   SD
Sbjct: 181  PHNTSGNGRAECRDGRDEQNCP--SCDEETEFQCVSDGRCIPIIYRCNGRPECTDR--SD 348

Query: 2815 EKNC 2818
            E +C
Sbjct: 349  EDSC 360

 Score = 42.7 bits (99), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 24/76 (31%), Positives = 36/76 (47%)
 Frame = +1

Query: 1170 DGDKDCVDGSDEAGCVLNCTSSQFKCADGSSCINSRYRCDGVYDCKDNSDEAGCPTRPPG 1229
            +G  +C DG DE  C      ++F+C     CI   YRC+G  +C D SDE  C  R   
Sbjct: 199  NGRAECRDGRDEQNCPSCDEETEFQCVSDGRCIPIIYRCNGRPECTDRSDEDSCQLRIEV 378

Query: 1230 MCHPDEFQCQGDGTCI 1245
            + +P   + +   T +
Sbjct: 379  VVNPLNLRVRTGQTAV 426

 Score = 42.7 bits (99), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 26/62 (41%), Positives = 34/62 (54%)
 Frame = +3

Query: 2865 CRSNEFQCVSPHRCIPSYWFCDGEADCVDSSDEPDTCGHSLNSCSANQFHCDNGRCISSS 2924
            CR +EF C +   CIP+   CD  +DC D SDE D CG     CS  +  CD GRC+   
Sbjct: 24   CREDEFTCETSRDCIPASRRCDRRSDCDDGSDERD-CGP---VCSEGELECD-GRCLPPQ 188

Query: 2925 WV 2926
            ++
Sbjct: 189  YI 194

 Score = 33.1 bits (74), Expect(2) = 0.006,   Method: Compositional matrix adjust.
 Identities = 20/59 (33%), Positives = 32/59 (54%), Gaps = 1/59 (1%)
 Frame = +3

Query: 183 CSQKEFQC-GSGECILRAYVCDHDNDCEDNSDEHNCNYDTCGGHQFTCSNGQCINQNWV 240
           C + EF C  S +CI  +  CD  +DC+D SDE +C    C   +  C +G+C+   ++
Sbjct: 24  CREDEFTCETSRDCIPASRRCDRRSDCDDGSDERDCGP-VCSEGELEC-DGRCLPPQYI 194

 Score = 28.1 bits (61), Expect(2) = 0.006,   Method: Compositional matrix adjust.
 Identities = 12/31 (38%), Positives = 19/31 (61%)
 Frame = +1

Query: 269 EWACPGSGRCISMDKVCDGVPDCPEGEDENN 299
           E+ C   GRCI +   C+G P+C +  DE++
Sbjct: 265 EFQCVSDGRCIPIIYRCNGRPECTDRSDEDS 357

 Score = 41.6 bits (96), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 26/60 (43%), Positives = 31/60 (51%), Gaps = 1/60 (1%)
 Frame = +3

Query: 2742 CRSTAFTCANGR-CVPYHYRCDFYNDCGDNSDEAGCLFRSCNSTTEFTCSNGRCIPLSYV 2800
            CR   FTC   R C+P   RCD  +DC D SDE  C      S  E  C +GRC+P  Y+
Sbjct: 24   CREDEFTCETSRDCIPASRRCDRRSDCDDGSDERDCG--PVCSEGELEC-DGRCLPPQYI 194

 Score = 31.6 bits (70), Expect(2) = 0.009,   Method: Compositional matrix adjust.
 Identities = 16/34 (47%), Positives = 21/34 (61%), Gaps = 1/34 (2%)
 Frame = +1

Query: 2999 EFSC-ANGRCIRQSFRCDRRNDCGDYSDERGCSY 3031
            EF C ++GRCI   +RC+ R +C D SDE  C  
Sbjct: 265  EFQCVSDGRCIPIIYRCNGRPECTDRSDEDSCQL 366

 Score = 28.9 bits (63), Expect(2) = 0.009,   Method: Compositional matrix adjust.
 Identities = 23/67 (34%), Positives = 32/67 (47%), Gaps = 1/67 (1%)
 Frame = +3

Query: 2908 CSANQFHCDNGR-CISSSWVCDGDNDCGDMSDEDQRHHCELQNCSSTEFTCINSRPPNRR 2966
            C  ++F C+  R CI +S  CD  +DC D SDE     C    CS  E  C      + R
Sbjct: 24   CREDEFTCETSRDCIPASRRCDRRSDCDDGSDE---RDC-GPVCSEGELEC------DGR 173

Query: 2967 CIPQHWV 2973
            C+P  ++
Sbjct: 174  CLPPQYI 194

 Score = 40.4 bits (93), Expect = 0.017,   Method: Compositional matrix adjust.
 Identities = 21/55 (38%), Positives = 31/55 (56%), Gaps = 1/55 (1%)
 Frame = +3

Query: 148 DQLTCANGA-CYNTSQKCDHKVDCRDSSDEANCTTLCSQKEFQCGSGECILRAYV 201
           D+ TC     C   S++CD + DC D SDE +C  +CS+ E +C  G C+   Y+
Sbjct: 33  DEFTCETSRDCIPASRRCDRRSDCDDGSDERDCGPVCSEGELEC-DGRCLPPQYI 194

 Score = 40.0 bits (92), Expect = 0.019,   Method: Compositional matrix adjust.
 Identities = 19/34 (55%), Positives = 23/34 (67%)
 Frame = +1

Query: 2868 NEFQCVSPHRCIPSYWFCDGEADCVDSSDEPDTC 2901
             EFQCVS  RCIP  + C+G  +C D SDE D+C
Sbjct: 262  TEFQCVSDGRCIPIIYRCNGRPECTDRSDE-DSC 360

 Score = 39.7 bits (91), Expect = 0.028,   Method: Compositional matrix adjust.
 Identities = 20/54 (37%), Positives = 30/54 (55%)
 Frame = +1

Query: 1045 DGVDDCHDNSDEHQCGALNNTCSSSAFTCVHGGQCIPGQWRCDKQNDCLDGSDE 1098
            +G  +C D  DE  C + +     + F CV  G+CIP  +RC+ + +C D SDE
Sbjct: 199  NGRAECRDGRDEQNCPSCDE---ETEFQCVSDGRCIPIIYRCNGRPECTDRSDE 351

 Score = 39.7 bits (91), Expect = 0.029,   Method: Compositional matrix adjust.
 Identities = 21/43 (48%), Positives = 26/43 (60%), Gaps = 1/43 (2%)
 Frame = +3

Query: 101 QNCPGTTCSSQQLTCSNGQ-CVPIEYRCDHVSDCPDGSDERNC 142
           +NCP   C   + TC   + C+P   RCD  SDC DGSDER+C
Sbjct: 12  RNCP---CREDEFTCETSRDCIPASRRCDRRSDCDDGSDERDC 131

 Score = 39.3 bits (90), Expect = 0.034,   Method: Compositional matrix adjust.
 Identities = 20/50 (40%), Positives = 30/50 (60%)
 Frame = +1

Query: 3505 RDRTLCMPMCSSTQFLCGNNEKCIPIWWKCDGQKDCSDGSDESDLCPHRF 3554
            RD   C      T+F C ++ +CIPI ++C+G+ +C+D SDE D C  R 
Sbjct: 226  RDEQNCPSCDEETEFQCVSDGRCIPIIYRCNGRPECTDRSDE-DSCQLRI 372

 Score = 33.9 bits (76), Expect(2) = 0.044,   Method: Compositional matrix adjust.
 Identities = 23/63 (36%), Positives = 33/63 (52%), Gaps = 2/63 (3%)
 Frame = +1

Query: 3906 NGVDDCGDGSDEKE-EHCRKPTHKPCTDTEYKC-SNGNCVSQHYVCDNVDDCGDLSDETG 3963
            NG  +C DG DE+    C +       +TE++C S+G C+   Y C+   +C D SDE  
Sbjct: 199  NGRAECRDGRDEQNCPSCDE-------ETEFQCVSDGRCIPIIYRCNGRPECTDRSDEDS 357

Query: 3964 CNL 3966
            C L
Sbjct: 358  CQL 366

 Score = 23.9 bits (50), Expect(2) = 0.044,   Method: Compositional matrix adjust.
 Identities = 14/33 (42%), Positives = 18/33 (54%), Gaps = 1/33 (3%)
 Frame = +3

Query: 3844 CPAAMFECK-NHVCIQSFWICDGENDCVDGSDE 3875
            C    F C+ +  CI +   CD  +DC DGSDE
Sbjct: 24   CREDEFTCETSRDCIPASRRCDRRSDCDDGSDE 122

 Score = 38.9 bits (89), Expect = 0.049,   Method: Compositional matrix adjust.
 Identities = 24/59 (40%), Positives = 33/59 (55%), Gaps = 1/59 (1%)
 Frame = +3

Query: 3033 PCRDDQFTCQNGQ-CITKLYVCDEDNDCGDGSDEQEHLCHTPEPTCPPHQFRCDNGHCI 3090
            PCR+D+FTC+  + CI     CD  +DC DGSDE++       P C   +  CD G C+
Sbjct: 21   PCREDEFTCETSRDCIPASRRCDRRSDCDDGSDERDCG-----PVCSEGELECD-GRCL 179

 Score = 37.0 bits (84), Expect = 0.18,   Method: Compositional matrix adjust.
 Identities = 17/36 (47%), Positives = 22/36 (61%), Gaps = 1/36 (2%)
 Frame = +1

Query: 2745 TAFTC-ANGRCVPYHYRCDFYNDCGDNSDEAGCLFR 2779
            T F C ++GRC+P  YRC+   +C D SDE  C  R
Sbjct: 262  TEFQCVSDGRCIPIIYRCNGRPECTDRSDEDSCQLR 369

 Score = 29.6 bits (65), Expect(2) = 0.22,   Method: Compositional matrix adjust.
 Identities = 21/52 (40%), Positives = 30/52 (57%), Gaps = 3/52 (5%)
 Frame = +1

Query: 3620 DCLDNSDED--PSHCASRTCRPGQFKC-NNGRCIPQSWKCDVDNDCGDYSDE 3668
            +C D  DE   PS C   T    +F+C ++GRCIP  ++C+   +C D SDE
Sbjct: 211  ECRDGRDEQNCPS-CDEET----EFQCVSDGRCIPIIYRCNGRPECTDRSDE 351

 Score = 25.8 bits (55), Expect(2) = 0.22,   Method: Compositional matrix adjust.
 Identities = 20/60 (33%), Positives = 27/60 (45%), Gaps = 1/60 (1%)
 Frame = +3

Query: 3555 CRLGQFQCRDG-NCTSPQALCNARQDCADGSDEDRVLCEHHRCEANEWQCANKRCIPEYW 3613
            CR  +F C    +C      C+ R DC DGSDE         C   E +C + RC+P  +
Sbjct: 24   CREDEFTCETSRDCIPASRRCDRRSDCDDGSDERDC---GPVCSEGELEC-DGRCLPPQY 191

 Score = 36.2 bits (82), Expect = 0.31,   Method: Compositional matrix adjust.
 Identities = 20/53 (37%), Positives = 32/53 (60%), Gaps = 4/53 (7%)
 Frame = +1

Query: 131 SDCPDGSDERNCYYPTCDQLT----CANGACYNTSQKCDHKVDCRDSSDEANC 179
           ++C DG DE+NC  P+CD+ T     ++G C     +C+ + +C D SDE +C
Sbjct: 208 AECRDGRDEQNC--PSCDEETEFQCVSDGRCIPIIYRCNGRPECTDRSDEDSC 360

 Score = 36.2 bits (82), Expect = 0.31,   Method: Compositional matrix adjust.
 Identities = 15/33 (45%), Positives = 23/33 (69%), Gaps = 1/33 (3%)
 Frame = +1

Query: 1028 SSFPC-NNGKCVPSIFRCDGVDDCHDNSDEHQC 1059
            + F C ++G+C+P I+RC+G  +C D SDE  C
Sbjct: 262  TEFQCVSDGRCIPIIYRCNGRPECTDRSDEDSC 360

 Score = 34.7 bits (78), Expect = 0.94,   Method: Compositional matrix adjust.
 Identities = 24/55 (43%), Positives = 30/55 (54%), Gaps = 2/55 (3%)
 Frame = +1

Query: 3535 DGQKDCSDGSDESDLCPHRFC-RLGQFQC-RDGNCTSPQALCNARQDCADGSDED 3587
            +G+ +C DG DE + CP   C    +FQC  DG C      CN R +C D SDED
Sbjct: 199  NGRAECRDGRDEQN-CPS--CDEETEFQCVSDGRCIPIIYRCNGRPECTDRSDED 354

 Score = 33.1 bits (74), Expect = 2.7,   Method: Compositional matrix adjust.
 Identities = 20/53 (37%), Positives = 29/53 (54%), Gaps = 1/53 (1%)
 Frame = +1

Query: 48  DGTRDCLDDTDEIGCPPRSCGSGF-FLCPAEGTCIPSSWVCDQDKDCSDGADE 99
           +G  +C D  DE  CP  SC     F C ++G CIP  + C+   +C+D +DE
Sbjct: 199 NGRAECRDGRDEQNCP--SCDEETEFQCVSDGRCIPIIYRCNGRPECTDRSDE 351

 Score = 33.1 bits (74), Expect = 2.8,   Method: Compositional matrix adjust.
 Identities = 24/65 (36%), Positives = 34/65 (52%), Gaps = 2/65 (3%)
 Frame = +1

Query: 2886 DGEADCVDSSDEPDTCGHSLNSC-SANQFHC-DNGRCISSSWVCDGDNDCGDMSDEDQRH 2943
            +G A+C D  DE      +  SC    +F C  +GRCI   + C+G  +C D SDED   
Sbjct: 199  NGRAECRDGRDE-----QNCPSCDEETEFQCVSDGRCIPIIYRCNGRPECTDRSDED--- 354

Query: 2944 HCELQ 2948
             C+L+
Sbjct: 355  SCQLR 369

 Score = 32.0 bits (71), Expect = 6.4,   Method: Compositional matrix adjust.
 Identities = 20/51 (39%), Positives = 30/51 (58%), Gaps = 2/51 (3%)
 Frame = +1

Query: 3017 RNDCGDYSDERGCSYPPCRDD-QFTC-QNGQCITKLYVCDEDNDCGDGSDE 3065
            R +C D  DE+ C  P C ++ +F C  +G+CI  +Y C+   +C D SDE
Sbjct: 205  RAECRDGRDEQNC--PSCDEETEFQCVSDGRCIPIIYRCNGRPECTDRSDE 351

 Score = 32.0 bits (71), Expect = 6.5,   Method: Compositional matrix adjust.
 Identities = 23/68 (33%), Positives = 35/68 (51%), Gaps = 1/68 (1%)
 Frame = +3

Query: 3882 NVPCESPQRFRCDNSR-CIYGHQLCNGVDDCGDGSDEKEEHCRKPTHKPCTDTEYKCSNG 3940
            N PC   + F C+ SR CI   + C+   DC DGSDE++          C++ E +C +G
Sbjct: 15   NCPCREDE-FTCETSRDCIPASRRCDRRSDCDDGSDERD------CGPVCSEGELEC-DG 170

Query: 3941 NCVSQHYV 3948
             C+   Y+
Sbjct: 171  RCLPPQYI 194

 Score = 31.2 bits (69), Expect = 9.6,   Method: Compositional matrix adjust.
 Identities = 15/34 (44%), Positives = 21/34 (61%), Gaps = 1/34 (2%)
 Frame = +1

Query: 33  FRC-DNGYCIPASWRCDGTRDCLDDTDEIGCPPR 65
           F+C  +G CIP  +RC+G  +C D +DE  C  R
Sbjct: 268 FQCVSDGRCIPIIYRCNGRPECTDRSDEDSCQLR 369
>28816
          Length = 437

 Score = 62.4 bits (150), Expect = 4e-09,   Method: Compositional matrix adjust.
 Identities = 31/57 (54%), Positives = 35/57 (61%), Gaps = 1/57 (1%)
 Frame = +3

Query: 1361 CTHRCIQGPFGATCVCPIGYQLANDTKTCEDVNEC-DIPGFCSQHCVNMRGSFRCAC 1416
            CTHRC+    GA C CP GYQLA+D  TC+D NEC +  G C   C N  GSF C C
Sbjct: 132  CTHRCVNTAGGAHCTCPRGYQLADDNTTCQDTNECTNSNGGCEDVCTNTEGSFECEC 302

 Score = 49.3 bits (116), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 26/73 (35%), Positives = 39/73 (53%), Gaps = 1/73 (1%)
 Frame = +3

Query: 3113 INECQDSSISHCDHNCTDTITSFYCSCLPGYKLMSDKRTCVDIDECKETPQLCSQKCENV 3172
            ++EC+   +  C H C +T    +C+C  GY+L  D  TC D +EC  +   C   C N 
Sbjct: 102  VDECETGQL-RCTHRCVNTAGGAHCTCPRGYQLADDNTTCQDTNECTNSNGGCEDVCTNT 278

Query: 3173 IGSYICKCA-PGY 3184
             GS+ C+C  PG+
Sbjct: 279  EGSFECECTKPGF 317

 Score = 38.1 bits (87), Expect(2) = 0.002,   Method: Compositional matrix adjust.
 Identities = 19/34 (55%), Positives = 22/34 (64%)
 Frame = +2

Query: 3148 DKRTCVDIDECKETPQLCSQKCENVIGSYICKCA 3181
            DKR CVDI+EC     LC  +CEN+ GSY C C 
Sbjct: 329  DKRQCVDINECL-NKSLCEGRCENLYGSYRCHCT 427

 Score = 24.3 bits (51), Expect(2) = 0.002,   Method: Compositional matrix adjust.
 Identities = 15/38 (39%), Positives = 22/38 (57%), Gaps = 1/38 (2%)
 Frame = +3

Query: 3113 INECQDSSISHCDHNCTDTITSFYCSCL-PGYKLMSDK 3149
             NEC +S+   C+  CT+T  SF C C  PG++L   +
Sbjct: 225  TNECTNSN-GGCEDVCTNTEGSFECECTKPGFRLSQTR 335

 Score = 41.6 bits (96), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 24/72 (33%), Positives = 35/72 (48%), Gaps = 1/72 (1%)
 Frame = +3

Query: 3124 CDHNCTDTITSFYCSCL-PGYKLMSDKRTCVDIDECKETPQLCSQKCENVIGSYICKCAP 3182
            C   C +T  S+ C+C  P Y L  +  +C D+DEC+     C+ +C N  G   C C  
Sbjct: 6    CHQLCINTPGSYNCNCTHPLYTLNRNGYSCDDVDECETGQLRCTHRCVNTAGGAHCTCPR 185

Query: 3183 GYIREPDGKSCR 3194
            GY    D  +C+
Sbjct: 186  GYQLADDNTTCQ 221

 Score = 40.8 bits (94), Expect = 0.012,   Method: Compositional matrix adjust.
 Identities = 35/99 (35%), Positives = 48/99 (48%), Gaps = 2/99 (2%)
 Frame = +3

Query: 3947 YVCDNVDDCGDLSDETGCNLGENRTCAEKICEQNCTQLSNGGFICSCRPGFKPSTLDKNS 4006
            Y CD+VD+C     ETG          +  C   C   + GG  C+C  G++ +  D  +
Sbjct: 87   YSCDDVDEC-----ETG----------QLRCTHRCVNTA-GGAHCTCPRGYQLAD-DNTT 215

Query: 4007 CQDINECEEF-GICPQSCRNSKGSYECFCVD-GFKSMST 4043
            CQD NEC    G C   C N++GS+EC C   GF+   T
Sbjct: 216  CQDTNECTNSNGGCEDVCTNTEGSFECECTKPGFRLSQT 332

 Score = 38.9 bits (89), Expect = 0.046,   Method: Compositional matrix adjust.
 Identities = 27/75 (36%), Positives = 35/75 (46%), Gaps = 3/75 (4%)
 Frame = +3

Query: 1361 CTHRCIQGPFGATCVC--PIGYQLANDTKTCEDVNECDIPGF-CSQHCVNMRGSFRCACD 1417
            C   CI  P    C C  P+ Y L  +  +C+DV+EC+     C+  CVN  G   C C 
Sbjct: 6    CHQLCINTPGSYNCNCTHPL-YTLNRNGYSCDDVDECETGQLRCTHRCVNTAGGAHCTCP 182

Query: 1418 PEYTLESDGRTCKVT 1432
              Y L  D  TC+ T
Sbjct: 183  RGYQLADDNTTCQDT 227

 Score = 33.9 bits (76), Expect(2) = 0.62,   Method: Compositional matrix adjust.
 Identities = 15/36 (41%), Positives = 19/36 (52%)
 Frame = +2

Query: 1381 QLANDTKTCEDVNECDIPGFCSQHCVNMRGSFRCAC 1416
            Q   D + C D+NEC     C   C N+ GS+RC C
Sbjct: 317  QTQPDKRQCVDINECLNKSLCEGRCENLYGSYRCHC 424

 Score = 20.0 bits (40), Expect(2) = 0.62,   Method: Compositional matrix adjust.
 Identities = 23/77 (29%), Positives = 35/77 (45%), Gaps = 6/77 (7%)
 Frame = +3

Query: 1313 CPSSQWQCPGYSICVNLSALCDGVFDCPNG---TDESPLC-NQDSCLHFNGGCTHRC--I 1366
            C + Q +C     CVN +        CP G    D++  C + + C + NGGC   C   
Sbjct: 111  CETGQLRCT--HRCVNTAG--GAHCTCPRGYQLADDNTTCQDTNECTNSNGGCEDVCTNT 278

Query: 1367 QGPFGATCVCPIGYQLA 1383
            +G F   C  P G++L+
Sbjct: 279  EGSFECECTKP-GFRLS 326

 Score = 33.9 bits (76), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 16/33 (48%), Positives = 17/33 (51%)
 Frame = +2

Query: 4003 DKNSCQDINECEEFGICPQSCRNSKGSYECFCV 4035
            DK  C DINEC    +C   C N  GSY C C 
Sbjct: 329  DKRQCVDINECLNKSLCEGRCENLYGSYRCHCT 427

 Score = 32.7 bits (73), Expect = 3.2,   Method: Compositional matrix adjust.
 Identities = 22/69 (31%), Positives = 38/69 (55%), Gaps = 2/69 (2%)
 Frame = +3

Query: 314 LNCEYQCHQTPYGGECFCPPGHIINSNDSRTCIDFDDC-QIWGICDQKCESRQGRHQCLC 372
           L C ++C  T  G  C CP G+ + ++D+ TC D ++C    G C+  C + +G  +C C
Sbjct: 126 LRCTHRCVNTAGGAHCTCPRGYQL-ADDNTTCQDTNECTNSNGGCEDVCTNTEGSFECEC 302

Query: 373 EE-GYILER 380
            + G+ L +
Sbjct: 303 TKPGFRLSQ 329
>35170
          Length = 598

 Score = 62.4 bits (150), Expect = 5e-09,   Method: Compositional matrix adjust.
 Identities = 43/149 (28%), Positives = 70/149 (46%), Gaps = 5/149 (3%)
 Frame = +2

Query: 1586 DGTMRTVIVQEKIYWPCGLSIDYPNRLIYFMDAYLDYIEFCDYDGQNRRQV----IASDL 1641
            DG  R V VQ  +     L++D P+  +Y++D     I      G    +       S  
Sbjct: 2    DGGDRQVFVQVDMLHLDHLTLDLPSNHLYWVDTSSHTIHRLPLGGDTADRASNIQTLSMR 181

Query: 1642 VLHHPHALTLFEDSVFWTDRGTHQVMQANKWHGRNQSVVMYSVPQPLGIIAIHPSRQPSS 1701
             +HHP  L + ED + W+++ T  V+ ANKW G+ +  ++       G+  +H + QP++
Sbjct: 182  GVHHPTGLVVVEDRLIWSEKKTGAVIAANKWTGKGRRRIVKHRQGVNGLSVLHAAIQPNA 361

Query: 1702 P-NPCASATCSHLCLLSAQEPRHYSCACP 1729
              N C  A C  +C+ S Q P  + C CP
Sbjct: 362  GDNACLRAQCHTMCVESKQWPG-FKCLCP 445

 Score = 49.7 bits (117), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 41/150 (27%), Positives = 62/150 (41%), Gaps = 7/150 (4%)
 Frame = +2

Query: 3354 DGTNKTVIISTKIEWPNAITIDYTNDLLYWADAHLGYIEFSDLEG------HHRHTVYDG 3407
            DG ++ V +   +   + +T+D  ++ LYW D     I    L G       +  T+   
Sbjct: 2    DGGDRQVFVQVDMLHLDHLTLDLPSNHLYWVDTSSHTIHRLPLGGDTADRASNIQTLSMR 181

Query: 3408 TLPHPFALTIFEDTVFWTDWNTRTVEKGNKYDGSGRVVLVNTTHKPFDIHVLHPYRQPIM 3467
             + HP  L + ED + W++  T  V   NK+ G GR  +V        + VLH   QP  
Sbjct: 182  GVHHPTGLVVVEDRLIWSEKKTGAVIAANKWTGKGRRRIVKHRQGVNGLSVLHAAIQPNA 361

Query: 3468 S-NPCATNNGGCSHLCLIKAGGRGFTCECP 3496
              N C      C  +C+      GF C CP
Sbjct: 362  GDNACL--RAQCHTMCVESKQWPGFKCLCP 445

 Score = 46.2 bits (108), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 46/157 (29%), Positives = 74/157 (47%), Gaps = 9/157 (5%)
 Frame = +2

Query: 543 DGSNRKDLVTTKLGWPAGITLDLVSKRVYWVDSRYDYIETVTYDGIQRKTVARGGSL--- 599
           DG +R+  V   +     +TLDL S  +YWVD+    I  +   G      +   +L   
Sbjct: 2   DGGDRQVFVQVDMLHLDHLTLDLPSNHLYWVDTSSHTIHRLPLGGDTADRASNIQTLSMR 181

Query: 600 -VPHPFGISLFEEHVFFTDWTKMAVMKANKFTDTNPQ--VYHQSSLTPFGVTVYHALRQP 656
            V HP G+ + E+ + +++    AV+ ANK+T    +  V H+  +   G++V HA  QP
Sbjct: 182 GVHHPTGLVVVEDRLIWSEKKTGAVIAANKWTGKGRRRIVKHRQGVN--GLSVLHAAIQP 355

Query: 657 NATNPCGNN---NGGCAQICVLSHRTDNGGLGYRCKC 690
           NA    G+N      C  +CV S +      G++C C
Sbjct: 356 NA----GDNACLRAQCHTMCVESKQWP----GFKCLC 442

 Score = 35.8 bits (81), Expect = 0.39,   Method: Compositional matrix adjust.
 Identities = 26/89 (29%), Positives = 44/89 (49%), Gaps = 10/89 (11%)
 Frame = +2

Query: 880 TSRLYWVDAFFDKIEHSNLDGLDRKRLGHVDQMT-----HPFGLTVFKDNVFLTDWRLGA 934
           ++ LYWVD     I    L G    R  ++  ++     HP GL V +D +  ++ + GA
Sbjct: 74  SNHLYWVDTSSHTIHRLPLGGDTADRASNIQTLSMRGVHHPTGLVVVEDRLIWSEKKTGA 253

Query: 935 IIRVRKSDG-GDMTVV--RRGIS--SIMH 958
           +I   K  G G   +V  R+G++  S++H
Sbjct: 254 VIAANKWTGKGRRRIVKHRQGVNGLSVLH 340

 Score = 34.7 bits (78), Expect = 0.90,   Method: Compositional matrix adjust.
 Identities = 22/70 (31%), Positives = 31/70 (44%), Gaps = 7/70 (10%)
 Frame = +2

Query: 2563 TDLLYWADASLQKIERSTLTG--SNREVVIST-----AFHSFGLTVYGQYIYWTDFYTKK 2615
            ++ LYW D S   I R  L G  ++R   I T       H  GL V    + W++  T  
Sbjct: 74   SNHLYWVDTSSHTIHRLPLGGDTADRASNIQTLSMRGVHHPTGLVVVEDRLIWSEKKTGA 253

Query: 2616 IYRANKYDGS 2625
            +  ANK+ G 
Sbjct: 254  VIAANKWTGK 283
>29665
          Length = 308

 Score = 60.5 bits (145), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 36/76 (47%), Positives = 45/76 (59%)
 Frame = +3

Query: 1139 SDEKNCQASGTCHPTQFRCPDHRCISPLYVCDGDKDCVDGSDEAGCVLNCTSSQFKCADG 1198
            SDE+NC  +      +F+C    CI     CDG  DC D SDEAGC  NCT+ +F C DG
Sbjct: 6    SDERNCDCN---FDFEFQCDMGVCIRSYERCDGKTDCPDQSDEAGCTPNCTNGRFTCDDG 176

Query: 1199 SSCINSRYRCDGVYDC 1214
             +CI + + CDG YDC
Sbjct: 177  -TCIMAEWVCDGQYDC 221

 Score = 56.6 bits (135), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 32/72 (44%), Positives = 39/72 (54%)
 Frame = +3

Query: 137 SDERNCYYPTCDQLTCANGACYNTSQKCDHKVDCRDSSDEANCTTLCSQKEFQCGSGECI 196
           SDERNC      +  C  G C  + ++CD K DC D SDEA CT  C+   F C  G CI
Sbjct: 6   SDERNCDCNFDFEFQCDMGVCIRSYERCDGKTDCPDQSDEAGCTPNCTNGRFTCDDGTCI 185

Query: 197 LRAYVCDHDNDC 208
           +  +VCD   DC
Sbjct: 186 MAEWVCDGQYDC 221

 Score = 56.6 bits (135), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 32/61 (52%), Positives = 39/61 (63%)
 Frame = +3

Query: 33  FRCDNGYCIPASWRCDGTRDCLDDTDEIGCPPRSCGSGFFLCPAEGTCIPSSWVCDQDKD 92
           F+CD G CI +  RCDG  DC D +DE GC P +C +G F C  +GTCI + WVCD   D
Sbjct: 45  FQCDMGVCIRSYERCDGKTDCPDQSDEAGCTP-NCTNGRFTCD-DGTCIMAEWVCDGQYD 218

Query: 93  C 93
           C
Sbjct: 219 C 221

 Score = 55.1 bits (131), Expect = 7e-07,   Method: Compositional matrix adjust.
 Identities = 31/61 (50%), Positives = 37/61 (60%)
 Frame = +3

Query: 2999 EFSCANGRCIRQSFRCDRRNDCGDYSDERGCSYPPCRDDQFTCQNGQCITKLYVCDEDND 3058
            EF C  G CIR   RCD + DC D SDE GC+ P C + +FTC +G CI   +VCD   D
Sbjct: 42   EFQCDMGVCIRSYERCDGKTDCPDQSDEAGCT-PNCTNGRFTCDDGTCIMAEWVCDGQYD 218

Query: 3059 C 3059
            C
Sbjct: 219  C 221

 Score = 54.7 bits (130), Expect = 8e-07,   Method: Compositional matrix adjust.
 Identities = 32/80 (40%), Positives = 41/80 (51%)
 Frame = +3

Query: 3790 SDERDCEMKTCHPEHFQCTSGHCVPKALACDGRADCLDASDESACPTRFPNGTYCPAAMF 3849
            SDER+C+        FQC  G C+     CDG+ DC D SDE+ C     NG       F
Sbjct: 6    SDERNCDCN--FDFEFQCDMGVCIRSYERCDGKTDCPDQSDEAGCTPNCTNG------RF 161

Query: 3850 ECKNHVCIQSFWICDGENDC 3869
             C +  CI + W+CDG+ DC
Sbjct: 162  TCDDGTCIMAEWVCDGQYDC 221

 Score = 52.4 bits (124), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 33/76 (43%), Positives = 41/76 (53%)
 Frame = +3

Query: 3711 SDEQGCESVPCHPSGDFRCGNHHCIPLRWKCDGIDDCGDNSDEESCVPRECTESEFRCAD 3770
            SDE+ C+   C+   +F+C    CI    +CDG  DC D SDE  C P  CT   F C D
Sbjct: 6    SDERNCD---CNFDFEFQCDMGVCIRSYERCDGKTDCPDQSDEAGCTPN-CTNGRFTCDD 173

Query: 3771 QQCIPSRWVCDQENDC 3786
              CI + WVCD + DC
Sbjct: 174  GTCIMAEWVCDGQYDC 221

 Score = 51.6 bits (122), Expect = 7e-06,   Method: Compositional matrix adjust.
 Identities = 32/63 (50%), Positives = 35/63 (55%)
 Frame = +3

Query: 1235 EFQCQGDGTCIPNTWECDGHPDCIQGSDEHNGCVPKTCSPSHFLCDNGNCIYNSWVCDGD 1294
            EFQC   G CI +   CDG  DC   SDE  GC P  C+   F CD+G CI   WVCDG 
Sbjct: 42   EFQCDM-GVCIRSYERCDGKTDCPDQSDEA-GCTPN-CTNGRFTCDDGTCIMAEWVCDGQ 212

Query: 1295 NDC 1297
             DC
Sbjct: 213  YDC 221

 Score = 50.8 bits (120), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 33/65 (50%), Positives = 39/65 (60%)
 Frame = +3

Query: 2869 EFQCVSPHRCIPSYWFCDGEADCVDSSDEPDTCGHSLNSCSANQFHCDNGRCISSSWVCD 2928
            EFQC     CI SY  CDG+ DC D SDE    G + N C+  +F CD+G CI + WVCD
Sbjct: 42   EFQC-DMGVCIRSYERCDGKTDCPDQSDEA---GCTPN-CTNGRFTCDDGTCIMAEWVCD 206

Query: 2929 GDNDC 2933
            G  DC
Sbjct: 207  GQYDC 221

 Score = 47.0 bits (110), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 29/63 (46%), Positives = 34/63 (53%)
 Frame = +3

Query: 1030 FPCNNGKCVPSIFRCDGVDDCHDNSDEHQCGALNNTCSSSAFTCVHGGQCIPGQWRCDKQ 1089
            F C+ G C+ S  RCDG  DC D SDE  C      C++  FTC   G CI  +W CD Q
Sbjct: 45   FQCDMGVCIRSYERCDGKTDCPDQSDEAGCTP---NCTNGRFTC-DDGTCIMAEWVCDGQ 212

Query: 1090 NDC 1092
             DC
Sbjct: 213  YDC 221

 Score = 45.1 bits (105), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 32/78 (41%), Positives = 38/78 (48%)
 Frame = +3

Query: 2730 SDELPTVCAFHTCRSTAFTCANGRCVPYHYRCDFYNDCGDNSDEAGCLFRSCNSTTEFTC 2789
            SDE    C F       F C  G C+  + RCD   DC D SDEAGC     N    FTC
Sbjct: 6    SDERNCDCNFDF----EFQCDMGVCIRSYERCDGKTDCPDQSDEAGCTPNCTNG--RFTC 167

Query: 2790 SNGRCIPLSYVCNGINNC 2807
             +G CI   +VC+G  +C
Sbjct: 168  DDGTCIMAEWVCDGQYDC 221

 Score = 42.7 bits (99), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 30/67 (44%), Positives = 33/67 (49%)
 Frame = +3

Query: 174 SDEANCTTLCSQKEFQCGSGECILRAYVCDHDNDCEDNSDEHNCNYDTCGGHQFTCSNGQ 233
           SDE NC       EFQC  G CI     CD   DC D SDE  C  + C   +FTC +G 
Sbjct: 6   SDERNCDCN-FDFEFQCDMGVCIRSYERCDGKTDCPDQSDEAGCTPN-CTNGRFTCDDGT 179

Query: 234 CINQNWV 240
           CI   WV
Sbjct: 180 CIMAEWV 200

 Score = 42.0 bits (97), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 28/74 (37%), Positives = 36/74 (48%), Gaps = 3/74 (4%)
 Frame = +3

Query: 3592 EHHRCEAN---EWQCANKRCIPEYWQCDSVDDCLDNSDEDPSHCASRTCRPGQFKCNNGR 3648
            +   C+ N   E+QC    CI  Y +CD   DC D SDE      +  C  G+F C++G 
Sbjct: 9    DERNCDCNFDFEFQCDMGVCIRSYERCDGKTDCPDQSDEAG---CTPNCTNGRFTCDDGT 179

Query: 3649 CIPQSWKCDVDNDC 3662
            CI   W CD   DC
Sbjct: 180  CIMAEWVCDGQYDC 221

 Score = 40.8 bits (94), Expect = 0.011,   Method: Compositional matrix adjust.
 Identities = 22/54 (40%), Positives = 32/54 (59%)
 Frame = +3

Query: 3527 CIPIWWKCDGQKDCSDGSDESDLCPHRFCRLGQFQCRDGNCTSPQALCNARQDC 3580
            CI  + +CDG+ DC D SDE+   P+  C  G+F C DG C   + +C+ + DC
Sbjct: 66   CIRSYERCDGKTDCPDQSDEAGCTPN--CTNGRFTCDDGTCIMAEWVCDGQYDC 221

 Score = 40.4 bits (93), Expect = 0.015,   Method: Compositional matrix adjust.
 Identities = 28/69 (40%), Positives = 34/69 (49%)
 Frame = +3

Query: 3679 NCDNHTEFSCKTNYRCIPQWAVCNGFDDCRDNSDEQGCESVPCHPSGDFRCGNHHCIPLR 3738
            +C+   EF C     CI  +  C+G  DC D SDE GC   P   +G F C +  CI   
Sbjct: 24   DCNFDFEFQCDMGV-CIRSYERCDGKTDCPDQSDEAGC--TPNCTNGRFTCDDGTCIMAE 194

Query: 3739 WKCDGIDDC 3747
            W CDG  DC
Sbjct: 195  WVCDGQYDC 221

 Score = 40.4 bits (93), Expect = 0.016,   Method: Compositional matrix adjust.
 Identities = 26/78 (33%), Positives = 36/78 (46%)
 Frame = +3

Query: 3882 NVPCESPQRFRCDNSRCIYGHQLCNGVDDCGDGSDEKEEHCRKPTHKPCTDTEYKCSNGN 3941
            N  C     F+CD   CI  ++ C+G  DC D SDE            CT+  + C +G 
Sbjct: 18   NCDCNFDFEFQCDMGVCIRSYERCDGKTDCPDQSDE------AGCTPNCTNGRFTCDDGT 179

Query: 3942 CVSQHYVCDNVDDCGDLS 3959
            C+   +VCD   DC  L+
Sbjct: 180  CIMAEWVCDGQYDCPRLN 233

 Score = 39.3 bits (90), Expect = 0.040,   Method: Compositional matrix adjust.
 Identities = 31/80 (38%), Positives = 36/80 (45%)
 Frame = +3

Query: 3023 YSDERGCSYPPCRDDQFTCQNGQCITKLYVCDEDNDCGDGSDEQEHLCHTPEPTCPPHQF 3082
            +SDER C      D +F C  G CI     CD   DC D SDE         P C   +F
Sbjct: 3    WSDERNCDCN--FDFEFQCDMGVCIRSYERCDGKTDCPDQSDEAGCT-----PNCTNGRF 161

Query: 3083 RCDNGHCIEMGTVCNHVDDC 3102
             CD+G CI    VC+   DC
Sbjct: 162  TCDDGTCIMAEWVCDGQYDC 221

 Score = 38.1 bits (87), Expect = 0.087,   Method: Compositional matrix adjust.
 Identities = 24/61 (39%), Positives = 30/61 (49%), Gaps = 2/61 (3%)
 Frame = +3

Query: 112 QLTCSNGQCVPIEYRCDHVSDCPDGSDERNCYYPTCD--QLTCANGACYNTSQKCDHKVD 169
           +  C  G C+    RCD  +DCPD SDE  C  P C   + TC +G C      CD + D
Sbjct: 42  EFQCDMGVCIRSYERCDGKTDCPDQSDEAGC-TPNCTNGRFTCDDGTCIMAEWVCDGQYD 218

Query: 170 C 170
           C
Sbjct: 219 C 221

 Score = 36.2 bits (82), Expect = 0.32,   Method: Compositional matrix adjust.
 Identities = 24/58 (41%), Positives = 28/58 (48%)
 Frame = +3

Query: 1118 DNHMCIPKEWVCDTDNDCSDGSDEKNCQASGTCHPTQFRCPDHRCISPLYVCDGDKDC 1175
            D  +CI     CD   DC D SDE  C  +  C   +F C D  CI   +VCDG  DC
Sbjct: 54   DMGVCIRSYERCDGKTDCPDQSDEAGCTPN--CTNGRFTCDDGTCIMAEWVCDGQYDC 221

 Score = 33.9 bits (76), Expect = 1.4,   Method: Compositional matrix adjust.
 Identities = 15/26 (57%), Positives = 17/26 (65%)
 Frame = +3

Query: 28  CGSGNFRCDNGYCIPASWRCDGTRDC 53
           C +G F CD+G CI A W CDG  DC
Sbjct: 144 CTNGRFTCDDGTCIMAEWVCDGQYDC 221
>25748
          Length = 425

 Score = 59.7 bits (143), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 34/72 (47%), Positives = 41/72 (56%), Gaps = 2/72 (2%)
 Frame = +2

Query: 1353 SCLHFNGGCTHRCIQGPFGA-TCVCPIGYQLANDTKTCEDVNEC-DIPGFCSQHCVNMRG 1410
            SC   NGGC   C+  P G   C C  GYQ+ +D   CEDVNEC ++ G C Q C N  G
Sbjct: 122  SCEQRNGGCEQLCVTEPGGEFRCDCYSGYQITSDGVHCEDVNECRELNGGCEQDCYNTEG 301

Query: 1411 SFRCACDPEYTL 1422
            S++CAC   Y L
Sbjct: 302  SYQCACQEGYIL 337

 Score = 51.2 bits (121), Expect = 9e-06,   Method: Compositional matrix adjust.
 Identities = 25/57 (43%), Positives = 31/57 (54%)
 Frame = +2

Query: 3129 TDTITSFYCSCLPGYKLMSDKRTCVDIDECKETPQLCSQKCENVIGSYICKCAPGYI 3185
            T+    F C C  GY++ SD   C D++EC+E    C Q C N  GSY C C  GYI
Sbjct: 164  TEPGGEFRCDCYSGYQITSDGVHCEDVNECRELNGGCEQDCYNTEGSYQCACQEGYI 334

 Score = 49.3 bits (116), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 28/63 (44%), Positives = 37/63 (58%), Gaps = 1/63 (1%)
 Frame = +2

Query: 3977 CEQNCTQLSNGGFICSCRPGFKPSTLDKNSCQDINECEEF-GICPQSCRNSKGSYECFCV 4035
            CEQ C     G F C C  G++  T D   C+D+NEC E  G C Q C N++GSY+C C 
Sbjct: 146  CEQLCVTEPGGEFRCDCYSGYQ-ITSDGVHCEDVNECRELNGGCEQDCYNTEGSYQCACQ 322

Query: 4036 DGF 4038
            +G+
Sbjct: 323  EGY 331

 Score = 44.3 bits (103), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 31/71 (43%), Positives = 43/71 (60%), Gaps = 3/71 (4%)
 Frame = +2

Query: 316 CEYQCHQTPYGGE--CFCPPGHIINSNDSRTCIDFDDC-QIWGICDQKCESRQGRHQCLC 372
           CE  C   P GGE  C C  G+ I S D   C D ++C ++ G C+Q C + +G +QC C
Sbjct: 146 CEQLCVTEP-GGEFRCDCYSGYQITS-DGVHCEDVNECRELNGGCEQDCYNTEGSYQCAC 319

Query: 373 EEGYILERGQH 383
           +EGYIL RG++
Sbjct: 320 QEGYILRRGRN 352

 Score = 38.5 bits (88), Expect = 0.056,   Method: Compositional matrix adjust.
 Identities = 16/41 (39%), Positives = 23/41 (56%)
 Frame = +2

Query: 2023 CSNNPNACQQICLPVPGGMFSCACASGFKLSPDGRSCSPYN 2063
            C      C+Q+C+  PGG F C C SG++++ DG  C   N
Sbjct: 125  CEQRNGGCEQLCVTEPGGEFRCDCYSGYQITSDGVHCEDVN 247

 Score = 34.7 bits (78), Expect = 0.84,   Method: Compositional matrix adjust.
 Identities = 26/67 (38%), Positives = 33/67 (49%), Gaps = 2/67 (2%)
 Frame = +2

Query: 1366 IQGPFGATCVCPIGYQLANDTKTCEDVNECDIP-GFCSQHCVNM-RGSFRCACDPEYTLE 1423
            ++G F   C CP    LA D   CE ++ C+   G C Q CV    G FRC C   Y + 
Sbjct: 44   LEGSF--ECSCPQHLVLAPDGLNCEAISSCEQRNGGCEQLCVTEPGGEFRCDCYSGYQIT 217

Query: 1424 SDGRTCK 1430
            SDG  C+
Sbjct: 218  SDGVHCE 238

 Score = 33.1 bits (74), Expect = 3.0,   Method: Compositional matrix adjust.
 Identities = 20/50 (40%), Positives = 28/50 (56%)
 Frame = +2

Query: 658 ATNPCGNNNGGCAQICVLSHRTDNGGLGYRCKCEFGFELDADEHHCVAVK 707
           A + C   NGGC Q+CV    T+ GG  +RC C  G+++ +D  HC  V 
Sbjct: 113 AISSCEQRNGGCEQLCV----TEPGGE-FRCDCYSGYQITSDGVHCEDVN 247

 Score = 31.6 bits (70), Expect = 8.0,   Method: Compositional matrix adjust.
 Identities = 13/34 (38%), Positives = 18/34 (52%)
 Frame = +2

Query: 1401 CSQHCVNMRGSFRCACDPEYTLESDGRTCKVTAS 1434
            C  +C N+ GSF C+C     L  DG  C+  +S
Sbjct: 23   CEYYCTNLEGSFECSCPQHLVLAPDGLNCEAISS 124
>11992
          Length = 1209

 Score = 59.3 bits (142), Expect = 4e-08,   Method: Compositional matrix adjust.
 Identities = 37/86 (43%), Positives = 47/86 (54%), Gaps = 5/86 (5%)
 Frame = +2

Query: 3113 INECQDSSISHCDHNCTDTITSFYCSCLPGYKLMSDKRTCVDIDECKETPQLCS--QKCE 3170
            INEC+  S   C HNC++T  S+ CSC  GY+L +D  +C DI+EC E    C   Q C 
Sbjct: 197  INECRLRS-DICQHNCSNTRGSYQCSCPKGYRLAADGYSCTDINECWEERIQCKEEQMCF 373

Query: 3171 NVIGSYIC---KCAPGYIREPDGKSC 3193
            N  GSY C    C   Y+R+P    C
Sbjct: 374  NTRGSYSCIDIPCPTNYVRDPATNYC 451

 Score = 53.5 bits (127), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 32/86 (37%), Positives = 41/86 (47%), Gaps = 7/86 (8%)
 Frame = +2

Query: 3115 ECQD-----SSISHCDHN--CTDTITSFYCSCLPGYKLMSDKRTCVDIDECKETPQLCSQ 3167
            ECQD     S+   C +N  C +    + C C  GY+     + CVDI+EC+    +C  
Sbjct: 56   ECQDVDECASNTHRCYNNQRCVNNDGGYRCQCPKGYRTRGIGQPCVDINECRLRSDICQH 235

Query: 3168 KCENVIGSYICKCAPGYIREPDGKSC 3193
             C N  GSY C C  GY    DG SC
Sbjct: 236  NCSNTRGSYQCSCPKGYRLAADGYSC 313

 Score = 44.3 bits (103), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 22/62 (35%), Positives = 36/62 (58%), Gaps = 1/62 (1%)
 Frame = +2

Query: 3985 SNGGFICSCRPGFKPSTLDKNSCQDINECE-EFGICPQSCRNSKGSYECFCVDGFKSMST 4043
            ++GG+ C C  G++   + +  C DINEC     IC  +C N++GSY+C C  G++  + 
Sbjct: 125  NDGGYRCQCPKGYRTRGIGQ-PCVDINECRLRSDICQHNCSNTRGSYQCSCPKGYRLAAD 301

Query: 4044 HY 4045
             Y
Sbjct: 302  GY 307

 Score = 43.9 bits (102), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 37/112 (33%), Positives = 47/112 (41%), Gaps = 9/112 (8%)
 Frame = +2

Query: 1312 HCPSSQWQCPGYSICVNLSALCDGVF--DCPNGTDE----SPLCNQDSCLHFNGGCTHRC 1365
             C S+  +C     CVN     DG +   CP G        P  + + C   +  C H C
Sbjct: 74   ECASNTHRCYNNQRCVNN----DGGYRCQCPKGYRTRGIGQPCVDINECRLRSDICQHNC 241

Query: 1366 IQGPFGATCVCPIGYQLANDTKTCEDVNEC---DIPGFCSQHCVNMRGSFRC 1414
                    C CP GY+LA D  +C D+NEC    I     Q C N RGS+ C
Sbjct: 242  SNTRGSYQCSCPKGYRLAADGYSCTDINECWEERIQCKEEQMCFNTRGSYSC 397

 Score = 40.8 bits (94), Expect = 0.012,   Method: Compositional matrix adjust.
 Identities = 27/61 (44%), Positives = 36/61 (59%), Gaps = 3/61 (4%)
 Frame = +2

Query: 3976 ICEQNCTQLSNGGFICSCRPGFKPSTLDKNSCQDINEC-EEFGICP--QSCRNSKGSYEC 4032
            IC+ NC+  + G + CSC  G++ +  D  SC DINEC EE   C   Q C N++GSY C
Sbjct: 224  ICQHNCSN-TRGSYQCSCPKGYRLAA-DGYSCTDINECWEERIQCKEEQMCFNTRGSYSC 397

Query: 4033 F 4033
             
Sbjct: 398  I 400

 Score = 35.0 bits (79), Expect = 0.69,   Method: Compositional matrix adjust.
 Identities = 18/54 (33%), Positives = 29/54 (53%), Gaps = 1/54 (1%)
 Frame = +2

Query: 326 GGECFCPPGHIINSNDSRTCIDFDDCQIWG-ICDQKCESRQGRHQCLCEEGYIL 378
           G  C CP G+       + C+D ++C++   IC   C + +G +QC C +GY L
Sbjct: 134 GYRCQCPKGYRTRG-IGQPCVDINECRLRSDICQHNCSNTRGSYQCSCPKGYRL 292
>34726
          Length = 626

 Score = 54.7 bits (130), Expect = 8e-07,   Method: Compositional matrix adjust.
 Identities = 35/99 (35%), Positives = 50/99 (50%), Gaps = 4/99 (4%)
 Frame = -1

Query: 3113 INECQDSSISHCDH--NCTDTITSFYCSCLPGYKL-MSDKRTCVDIDECKETPQLCSQKC 3169
            ++ECQ+S    CD    CT+T  SF CSC   Y++  +D   C DIDEC E    C Q C
Sbjct: 518  VDECQNSP---CDSVATCTNTDGSFVCSCPTHYRMDTTDMTQCTDIDECAENTDNCEQVC 348

Query: 3170 ENVIGSYICKCAPGY-IREPDGKSCRQNSNIEPYLVFSN 3207
             N  G + C C  G+ +      +C +++N +P     N
Sbjct: 347  NNTEGGFTCDCVAGFXLNATTNSTCDKDANQDPCASIXN 231

 Score = 46.2 bits (108), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 23/55 (41%), Positives = 32/55 (58%), Gaps = 1/55 (1%)
 Frame = -1

Query: 3985 SNGGFICSCRPGFKPSTLDKNSCQDINEC-EEFGICPQSCRNSKGSYECFCVDGF 4038
            ++G F+CSC   ++  T D   C DI+EC E    C Q C N++G + C CV GF
Sbjct: 467  TDGSFVCSCPTHYRMDTTDMTQCTDIDECAENTDNCEQVCNNTEGGFTCDCVAGF 303

 Score = 37.7 bits (86), Expect = 0.12,   Method: Compositional matrix adjust.
 Identities = 31/113 (27%), Positives = 49/113 (43%), Gaps = 4/113 (3%)
 Frame = -1

Query: 3076 TCPPHQFRCDNGHCIEMGTVCNHVDDCSDNSDEKGCGINECQDSSISHCDHNCTDTITSF 3135
            +CP H +R D     +M T C  +D+C++N+D               +C+  C +T   F
Sbjct: 446  SCPTH-YRMDT---TDM-TQCTDIDECAENTD---------------NCEQVCNNTEGGF 327

Query: 3136 YCSCLPGYKLMSDKRTCVDIDE----CKETPQLCSQKCENVIGSYICKCAPGY 3184
             C C+ G+ L +   +  D D     C      CS  C+N  G  +C C  G+
Sbjct: 326  TCDCVAGFXLNATTNSTCDKDANQDPCASIXNTCSYACQNDSGXAVCVCPKGF 168

 Score = 36.2 bits (82), Expect = 0.32,   Method: Compositional matrix adjust.
 Identities = 54/177 (30%), Positives = 67/177 (37%), Gaps = 10/177 (5%)
 Frame = -1

Query: 3882 NVPCESPQRFRCDNSRCIYGHQLCNGVDDCGDGSDEKEEHCRKPTHKPCTDTEYKCSNGN 3941
            N  CE   R  CD  R   G Q C  VD+C +   +    C        TD  + CS   
Sbjct: 584  NETCECRGRGTCDRVR---GCQ-CFDVDECQNSPCDSVATCTN------TDGSFVCS--- 444

Query: 3942 CVSQHYVCDNVD--DCGDLSDETGCNLGENRTCAEKI--CEQNCTQLSNGGFICSCRPGF 3997
                HY  D  D   C D+ +           CAE    CEQ C   + GGF C C  GF
Sbjct: 443  -CPTHYRMDTTDMTQCTDIDE-----------CAENTDNCEQVCNN-TEGGFTCDCVAGF 303

Query: 3998 -----KPSTLDKNSCQDINECEEF-GICPQSCRNSKGSYECFCVDGFKSMSTHYGER 4048
                   ST DK++ QD   C      C  +C+N  G   C C  GF   +T    +
Sbjct: 302  XLNATTNSTCDKDANQD--PCASIXNTCSYACQNDSGXAVCVCPKGFALTTTKQAVK 138

 Score = 34.3 bits (77), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 24/76 (31%), Positives = 32/76 (42%)
 Frame = -1

Query: 1350 NQDSCLHFNGGCTHRCIQGPFGATCVCPIGYQLANDTKTCEDVNECDIPGFCSQHCVNMR 1409
            NQD C      C++ C      A CVCP G+ L   TK    ++   +          M 
Sbjct: 260  NQDPCASIXNTCSYACQNDSGXAVCVCPKGFALTT-TKQAVKISMSAVRTCVLSLAPIMT 84

Query: 1410 GSFRCACDPEYTLESD 1425
            G + C+C P Y LE D
Sbjct: 83   GGYTCSCLPGYFLEED 36

 Score = 33.9 bits (76), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 22/73 (30%), Positives = 33/73 (45%), Gaps = 4/73 (5%)
 Frame = -1

Query: 315 NCEYQCHQTPYGGECFCPPGHIINSNDSRTC---IDFDDC-QIWGICDQKCESRQGRHQC 370
           NCE  C+ T  G  C C  G  +N+  + TC    + D C  I   C   C++  G   C
Sbjct: 365 NCEQVCNNTEGGFTCDCVAGFXLNATTNSTCDKDANQDPCASIXNTCSYACQNDSGXAVC 186

Query: 371 LCEEGYILERGQH 383
           +C +G+ L   + 
Sbjct: 185 VCPKGFALTTTKQ 147
>14371
          Length = 627

 Score = 54.3 bits (129), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 26/60 (43%), Positives = 38/60 (63%), Gaps = 2/60 (3%)
 Frame = +3

Query: 3134 SFYCS--CLPGYKLMSDKRTCVDIDECKETPQLCSQKCENVIGSYICKCAPGYIREPDGK 3191
            S+ CS  C  G++   D   C DI+EC +TP++C+Q C+N+IGSY C C  GY    +G+
Sbjct: 3    SYQCSAVCGNGFRRSQDGSKCEDINECADTPEVCAQSCQNLIGSYRCSCTRGYRLGDNGR 182

 Score = 51.2 bits (121), Expect = 9e-06,   Method: Compositional matrix adjust.
 Identities = 26/67 (38%), Positives = 38/67 (56%), Gaps = 1/67 (1%)
 Frame = +3

Query: 1370 FGATCVCPIGYQLANDTKTCEDVNEC-DIPGFCSQHCVNMRGSFRCACDPEYTLESDGRT 1428
            +  + VC  G++ + D   CED+NEC D P  C+Q C N+ GS+RC+C   Y L  +GR 
Sbjct: 6    YQCSAVCGNGFRRSQDGSKCEDINECADTPEVCAQSCQNLIGSYRCSCTRGYRLGDNGRC 185

Query: 1429 CKVTASE 1435
              +   E
Sbjct: 186  IDINECE 206

 Score = 39.7 bits (91), Expect = 0.025,   Method: Compositional matrix adjust.
 Identities = 22/48 (45%), Positives = 30/48 (62%), Gaps = 1/48 (2%)
 Frame = +3

Query: 3993 CRPGFKPSTLDKNSCQDINECEEF-GICPQSCRNSKGSYECFCVDGFK 4039
            C  GF+ S  D + C+DINEC +   +C QSC+N  GSY C C  G++
Sbjct: 24   CGNGFRRSQ-DGSKCEDINECADTPEVCAQSCQNLIGSYRCSCTRGYR 164

 Score = 38.1 bits (87), Expect = 0.080,   Method: Compositional matrix adjust.
 Identities = 18/40 (45%), Positives = 21/40 (52%)
 Frame = +3

Query: 3154 DIDECKETPQLCSQKCENVIGSYICKCAPGYIREPDGKSC 3193
            DI+EC+    +C   C N  GSY C C  GY    DG SC
Sbjct: 507  DINECRLRSDICQHNCSNTRGSYQCSCPKGYRLAADGYSC 626

 Score = 37.4 bits (85), Expect = 0.15,   Method: Compositional matrix adjust.
 Identities = 17/41 (41%), Positives = 26/41 (63%), Gaps = 1/41 (2%)
 Frame = +3

Query: 1390 EDVNECDIPG-FCSQHCVNMRGSFRCACDPEYTLESDGRTC 1429
            +D+NEC +    C  +C N RGS++C+C   Y L +DG +C
Sbjct: 504  DDINECRLRSDICQHNCSNTRGSYQCSCPKGYRLAADGYSC 626

 Score = 33.1 bits (74), Expect = 2.4,   Method: Compositional matrix adjust.
 Identities = 16/38 (42%), Positives = 23/38 (60%), Gaps = 1/38 (2%)
 Frame = +3

Query: 4009 DINECE-EFGICPQSCRNSKGSYECFCVDGFKSMSTHY 4045
            DINEC     IC  +C N++GSY+C C  G++  +  Y
Sbjct: 507  DINECRLRSDICQHNCSNTRGSYQCSCPKGYRLAADGY 620

 Score = 31.2 bits (69), Expect = 9.7,   Method: Compositional matrix adjust.
 Identities = 16/34 (47%), Positives = 18/34 (52%), Gaps = 3/34 (8%)
 Frame = +3

Query: 4334 NPCKQ---VCSHLCLLRPGGYSCACPQGSDFVTG 4364
            N C+Q    CSH C+  PG Y CACP G     G
Sbjct: 195  NECEQPSTKCSHDCVNTPGSYRCACPVGYRLTAG 296
>14599
          Length = 1135

 Score = 53.5 bits (127), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 32/85 (37%), Positives = 48/85 (56%), Gaps = 3/85 (3%)
 Frame = -2

Query: 3112 GINECQDSSIS-HCDHNCTDTITSFYCSCLPGYKLMSDKRTCVDIDECKETPQLCSQ--K 3168
            G + C ++S + H   +C  +  SF C C PGY+   +   C DIDEC     +C +  +
Sbjct: 339  GTDPCAEASQTCHAHADCVPSDQSFQCVCRPGYQ--GNGFDCQDIDECAIEVGVCDEXAR 166

Query: 3169 CENVIGSYICKCAPGYIREPDGKSC 3193
            C NV GS+ C+C PGY  + DG++C
Sbjct: 165  CFNVYGSFQCQCMPGY--QGDGRTC 97

 Score = 44.7 bits (104), Expect = 8e-04,   Method: Compositional matrix adjust.
 Identities = 24/58 (41%), Positives = 36/58 (62%), Gaps = 3/58 (5%)
 Frame = -2

Query: 3985 SNGGFICSCRPGFKPSTLDKNSCQDINECE-EFGICPQSCR--NSKGSYECFCVDGFK 4039
            S+  F C CRPG++ +  D   CQDI+EC  E G+C +  R  N  GS++C C+ G++
Sbjct: 279  SDQSFQCVCRPGYQGNGFD---CQDIDECAIEVGVCDEXARCFNVYGSFQCQCMPGYQ 115

 Score = 43.9 bits (102), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 27/59 (45%), Positives = 35/59 (59%), Gaps = 3/59 (5%)
 Frame = -2

Query: 1374 CVCPIGYQLANDTKTCEDVNECDIP-GFCSQ--HCVNMRGSFRCACDPEYTLESDGRTC 1429
            CVC  GYQ   +   C+D++EC I  G C +   C N+ GSF+C C P Y  + DGRTC
Sbjct: 261  CVCRPGYQ--GNGFDCQDIDECAIEVGVCDEXARCFNVYGSFQCQCMPGY--QGDGRTC 97
>11667
          Length = 1227

 Score = 50.8 bits (120), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 40/104 (38%), Positives = 50/104 (48%), Gaps = 22/104 (21%)
 Frame = +3

Query: 3113 INECQDSSISHCDHNCTDTITSFYC-------------------SCLPGYKLMSDKRTCV 3153
            INEC  S     ++ CT+T  S+ C                    C  GY L   K  C+
Sbjct: 519  INECDTSPCKDTEY-CTNTQGSYMCMSCNVACDGCTGSGPDHCVKCSAGYYLQDGK--CL 689

Query: 3154 DIDECKETPQLCS---QKCENVIGSYICKCAPGYIREPDGKSCR 3194
            D+DEC E  QLCS   Q CEN +GSY C+C PGY +   G +CR
Sbjct: 690  DMDECSEDGQLCSDEGQVCENTVGSYKCECQPGYNK--IGDACR 815
>27664
          Length = 1281

 Score = 48.1 bits (113), Expect = 8e-05,   Method: Compositional matrix adjust.
 Identities = 25/53 (47%), Positives = 30/53 (56%)
 Frame = +3

Query: 28  CGSGNFRCDNGYCIPASWRCDGTRDCLDDTDEIGCPPRSCGSGFFLCPAEGTC 80
           C SG+F+C  G C+ AS  CDGT DC D +DEI CP +    G    P E  C
Sbjct: 51  CSSGSFQCATGQCVQASRTCDGTEDCTDGSDEINCPSQC--KGMLRGPEETLC 203

 Score = 44.7 bits (104), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 23/56 (41%), Positives = 28/56 (50%), Gaps = 6/56 (10%)
 Frame = +3

Query: 3795 CEMKTCHPEHFQCTSGHCVPKALACDGRADCLDASDESACPT------RFPNGTYC 3844
            C++  C    FQC +G CV  +  CDG  DC D SDE  CP+      R P  T C
Sbjct: 36   CQLPACSSGSFQCATGQCVQASRTCDGTEDCTDGSDEINCPSQCKGMLRGPEETLC 203

 Score = 42.7 bits (99), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 23/52 (44%), Positives = 30/52 (57%), Gaps = 1/52 (1%)
 Frame = +3

Query: 1188 CTSSQFKCADGSSCINSRYRCDGVYDCKDNSDEAGCPTRPPGMCH-PDEFQC 1238
            C+S  F+CA G  C+ +   CDG  DC D SDE  CP++  GM   P+E  C
Sbjct: 51   CSSGSFQCATGQ-CVQASRTCDGTEDCTDGSDEINCPSQCKGMLRGPEETLC 203

 Score = 42.0 bits (97), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 20/40 (50%), Positives = 25/40 (62%)
 Frame = +3

Query: 2990 CTMRACSTGEFSCANGRCIRQSFRCDRRNDCGDYSDERGC 3029
            C + ACS+G F CA G+C++ S  CD   DC D SDE  C
Sbjct: 36   CQLPACSSGSFQCATGQCVQASRTCDGTEDCTDGSDEINC 155

 Score = 42.0 bits (97), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 20/43 (46%), Positives = 23/43 (53%)
 Frame = +3

Query: 1267 CVPKTCSPSHFLCDNGNCIYNSWVCDGDNDCRDMSDEKDCPTQ 1309
            C    CS   F C  G C+  S  CDG  DC D SDE +CP+Q
Sbjct: 36   CQLPACSSGSFQCATGQCVQASRTCDGTEDCTDGSDEINCPSQ 164

 Score = 39.7 bits (91), Expect = 0.030,   Method: Compositional matrix adjust.
 Identities = 17/35 (48%), Positives = 21/35 (60%)
 Frame = +3

Query: 183 CSQKEFQCGSGECILRAYVCDHDNDCEDNSDEHNC 217
           CS   FQC +G+C+  +  CD   DC D SDE NC
Sbjct: 51  CSSGSFQCATGQCVQASRTCDGTEDCTDGSDEINC 155

 Score = 39.3 bits (90), Expect = 0.036,   Method: Compositional matrix adjust.
 Identities = 19/35 (54%), Positives = 20/35 (57%)
 Frame = +3

Query: 108 CSSQQLTCSNGQCVPIEYRCDHVSDCPDGSDERNC 142
           CSS    C+ GQCV     CD   DC DGSDE NC
Sbjct: 51  CSSGSFQCATGQCVQASRTCDGTEDCTDGSDEINC 155

 Score = 39.3 bits (90), Expect = 0.038,   Method: Compositional matrix adjust.
 Identities = 19/41 (46%), Positives = 21/41 (51%)
 Frame = +3

Query: 2736 VCAFHTCRSTAFTCANGRCVPYHYRCDFYNDCGDNSDEAGC 2776
            VC    C S +F CA G+CV     CD   DC D SDE  C
Sbjct: 33   VCQLPACSSGSFQCATGQCVQASRTCDGTEDCTDGSDEINC 155

 Score = 38.9 bits (89), Expect = 0.046,   Method: Compositional matrix adjust.
 Identities = 17/35 (48%), Positives = 22/35 (62%)
 Frame = +3

Query: 2905 LNSCSANQFHCDNGRCISSSWVCDGDNDCGDMSDE 2939
            L +CS+  F C  G+C+ +S  CDG  DC D SDE
Sbjct: 42   LPACSSGSFQCATGQCVQASRTCDGTEDCTDGSDE 146

 Score = 38.9 bits (89), Expect = 0.054,   Method: Compositional matrix adjust.
 Identities = 22/49 (44%), Positives = 25/49 (51%)
 Frame = +3

Query: 1011 TCEGDPAREPPTQQCGSSSFPCNNGKCVPSIFRCDGVDDCHDNSDEHQC 1059
            TCE   A       C S SF C  G+CV +   CDG +DC D SDE  C
Sbjct: 9    TCEWKRAFVCQLPACSSGSFQCATGQCVQASRTCDGTEDCTDGSDEINC 155

 Score = 38.1 bits (87), Expect = 0.077,   Method: Compositional matrix adjust.
 Identities = 17/37 (45%), Positives = 18/37 (48%)
 Frame = +3

Query: 3029 CSYPPCRDDQFTCQNGQCITKLYVCDEDNDCGDGSDE 3065
            C  P C    F C  GQC+     CD   DC DGSDE
Sbjct: 36   CQLPACSSGSFQCATGQCVQASRTCDGTEDCTDGSDE 146

 Score = 37.0 bits (84), Expect = 0.16,   Method: Compositional matrix adjust.
 Identities = 18/43 (41%), Positives = 24/43 (55%)
 Frame = +3

Query: 3719 VPCHPSGDFRCGNHHCIPLRWKCDGIDDCGDNSDEESCVPREC 3761
            +P   SG F+C    C+     CDG +DC D SDE +C P +C
Sbjct: 42   LPACSSGSFQCATGQCVQASRTCDGTEDCTDGSDEINC-PSQC 167

 Score = 36.6 bits (83), Expect = 0.27,   Method: Compositional matrix adjust.
 Identities = 14/37 (37%), Positives = 20/37 (54%)
 Frame = +3

Query: 3075 PTCPPHQFRCDNGHCIEMGTVCNHVDDCSDNSDEKGC 3111
            P C    F+C  G C++    C+  +DC+D SDE  C
Sbjct: 45   PACSSGSFQCATGQCVQASRTCDGTEDCTDGSDEINC 155

 Score = 36.2 bits (82), Expect = 0.33,   Method: Compositional matrix adjust.
 Identities = 19/44 (43%), Positives = 21/44 (47%), Gaps = 2/44 (4%)
 Frame = +3

Query: 142 CYYPTCDQ--LTCANGACYNTSQKCDHKVDCRDSSDEANCTTLC 183
           C  P C      CA G C   S+ CD   DC D SDE NC + C
Sbjct: 36  CQLPACSSGSFQCATGQCVQASRTCDGTEDCTDGSDEINCPSQC 167

 Score = 36.2 bits (82), Expect = 0.33,   Method: Compositional matrix adjust.
 Identities = 16/39 (41%), Positives = 20/39 (51%)
 Frame = +3

Query: 1150 CHPTQFRCPDHRCISPLYVCDGDKDCVDGSDEAGCVLNC 1188
            C    F+C   +C+     CDG +DC DGSDE  C   C
Sbjct: 51   CSSGSFQCATGQCVQASRTCDGTEDCTDGSDEINCPSQC 167

 Score = 36.2 bits (82), Expect = 0.33,   Method: Compositional matrix adjust.
 Identities = 15/32 (46%), Positives = 19/32 (59%)
 Frame = +3

Query: 3844 CPAAMFECKNHVCIQSFWICDGENDCVDGSDE 3875
            C +  F+C    C+Q+   CDG  DC DGSDE
Sbjct: 51   CSSGSFQCATGQCVQASRTCDGTEDCTDGSDE 146

 Score = 35.4 bits (80), Expect = 0.50,   Method: Compositional matrix adjust.
 Identities = 19/43 (44%), Positives = 26/43 (60%)
 Frame = +3

Query: 3511 MPMCSSTQFLCGNNEKCIPIWWKCDGQKDCSDGSDESDLCPHR 3553
            +P CSS  F C   + C+     CDG +DC+DGSDE + CP +
Sbjct: 42   LPACSSGSFQCATGQ-CVQASRTCDGTEDCTDGSDEIN-CPSQ 164

 Score = 35.4 bits (80), Expect = 0.52,   Method: Compositional matrix adjust.
 Identities = 21/43 (48%), Positives = 27/43 (62%)
 Frame = +3

Query: 62  CPPRSCGSGFFLCPAEGTCIPSSWVCDQDKDCSDGADEQQNCP 104
           C   +C SG F C A G C+ +S  CD  +DC+DG+DE  NCP
Sbjct: 36  CQLPACSSGSFQC-ATGQCVQASRTCDGTEDCTDGSDE-INCP 158

 Score = 34.7 bits (78), Expect = 0.92,   Method: Compositional matrix adjust.
 Identities = 17/45 (37%), Positives = 24/45 (53%), Gaps = 2/45 (4%)
 Frame = +3

Query: 3590 LCEHHRCEANEWQCANKRCIPEYWQCDSVDDCLDNSDED--PSHC 3632
            +C+   C +  +QCA  +C+     CD  +DC D SDE   PS C
Sbjct: 33   VCQLPACSSGSFQCATGQCVQASRTCDGTEDCTDGSDEINCPSQC 167

 Score = 34.7 bits (78), Expect = 0.94,   Method: Compositional matrix adjust.
 Identities = 16/38 (42%), Positives = 19/38 (50%)
 Frame = +3

Query: 3549 LCPHRFCRLGQFQCRDGNCTSPQALCNARQDCADGSDE 3586
            +C    C  G FQC  G C      C+  +DC DGSDE
Sbjct: 33   VCQLPACSSGSFQCATGQCVQASRTCDGTEDCTDGSDE 146

 Score = 33.9 bits (76), Expect = 1.4,   Method: Compositional matrix adjust.
 Identities = 18/35 (51%), Positives = 20/35 (57%)
 Frame = +3

Query: 1066 CSSSAFTCVHGGQCIPGQWRCDKQNDCLDGSDEQN 1100
            CSS +F C  G QC+     CD   DC DGSDE N
Sbjct: 51   CSSGSFQCATG-QCVQASRTCDGTEDCTDGSDEIN 152

 Score = 33.9 bits (76), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 14/35 (40%), Positives = 19/35 (54%)
 Frame = +3

Query: 3930 CTDTEYKCSNGNCVSQHYVCDNVDDCGDLSDETGC 3964
            C+   ++C+ G CV     CD  +DC D SDE  C
Sbjct: 51   CSSGSFQCATGQCVQASRTCDGTEDCTDGSDEINC 155

 Score = 33.9 bits (76), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 18/44 (40%), Positives = 26/44 (59%)
 Frame = +3

Query: 2776 CLFRSCNSTTEFTCSNGRCIPLSYVCNGINNCHDNDTSDEKNCP 2819
            C   +C+S + F C+ G+C+  S  C+G  +C D   SDE NCP
Sbjct: 36   CQLPACSSGS-FQCATGQCVQASRTCDGTEDCTDG--SDEINCP 158

 Score = 33.5 bits (75), Expect = 1.9,   Method: Compositional matrix adjust.
 Identities = 14/36 (38%), Positives = 21/36 (58%)
 Frame = +3

Query: 3882 NVPCESPQRFRCDNSRCIYGHQLCNGVDDCGDGSDE 3917
             +P  S   F+C   +C+   + C+G +DC DGSDE
Sbjct: 39   QLPACSSGSFQCATGQCVQASRTCDGTEDCTDGSDE 146

 Score = 33.5 bits (75), Expect = 2.2,   Method: Compositional matrix adjust.
 Identities = 15/35 (42%), Positives = 20/35 (57%)
 Frame = +3

Query: 3761 CTESEFRCADQQCIPSRWVCDQENDCGDNSDERDC 3795
            C+   F+CA  QC+ +   CD   DC D SDE +C
Sbjct: 51   CSSGSFQCATGQCVQASRTCDGTEDCTDGSDEINC 155

 Score = 33.1 bits (74), Expect = 2.7,   Method: Compositional matrix adjust.
 Identities = 16/37 (43%), Positives = 19/37 (51%)
 Frame = +3

Query: 3632 CASRTCRPGQFKCNNGRCIPQSWKCDVDNDCGDYSDE 3668
            C    C  G F+C  G+C+  S  CD   DC D SDE
Sbjct: 36   CQLPACSSGSFQCATGQCVQASRTCDGTEDCTDGSDE 146

 Score = 31.2 bits (69), Expect = 9.4,   Method: Compositional matrix adjust.
 Identities = 16/43 (37%), Positives = 21/43 (48%)
 Frame = +3

Query: 2855 ENPIYCASHTCRSNEFQCVSPHRCIPSYWFCDGEADCVDSSDE 2897
            +    C    C S  FQC +  +C+ +   CDG  DC D SDE
Sbjct: 21   KRAFVCQLPACSSGSFQCAT-GQCVQASRTCDGTEDCTDGSDE 146
>25877
          Length = 434

 Score = 45.1 bits (105), Expect = 6e-04,   Method: Compositional matrix adjust.
 Identities = 23/63 (36%), Positives = 33/63 (52%), Gaps = 2/63 (3%)
 Frame = -1

Query: 3137 CSCLPGYKLMSDKRTCV--DIDECKETPQLCSQKCENVIGSYICKCAPGYIREPDGKSCR 3194
            C C  GY+L  D +TC+  D+D C + P  C Q C +  G + C C  G+   P  ++CR
Sbjct: 332  CFCNTGYQLDGDNKTCIFIDVDWCLQDPSPCDQTCNSTDGKFTCGCFKGFQLNPGNRTCR 153

Query: 3195 QNS 3197
              S
Sbjct: 152  ACS 144

 Score = 38.5 bits (88), Expect = 0.069,   Method: Compositional matrix adjust.
 Identities = 34/91 (37%), Positives = 41/91 (45%), Gaps = 3/91 (3%)
 Frame = -1

Query: 1346 SPLCNQDSCLHFNGGCTHRCIQGPFGATCVCPIGYQLANDTKTCE--DVNEC-DIPGFCS 1402
            S  C++  C   NGGC    I G     C C  GYQL  D KTC   DV+ C   P  C 
Sbjct: 404  STTCSELDCDLDNGGCK---IVGD-SQECFCNTGYQLDGDNKTCIFIDVDWCLQDPSPCD 237

Query: 1403 QHCVNMRGSFRCACDPEYTLESDGRTCKVTA 1433
            Q C +  G F C C   + L    RTC+  +
Sbjct: 236  QTCNSTDGKFTCGCFKGFQLNPGNRTCRACS 144

 Score = 33.5 bits (75), Expect = 2.0,   Method: Compositional matrix adjust.
 Identities = 29/79 (36%), Positives = 39/79 (49%), Gaps = 6/79 (7%)
 Frame = -1

Query: 311 CSILNCEYQ---CHQTPYGGECFCPPGHIINSNDSRTCI--DFDDC-QIWGICDQKCESR 364
           CS L+C+     C       ECFC  G+ ++  D++TCI  D D C Q    CDQ C S 
Sbjct: 395 CSELDCDLDNGGCKIVGDSQECFCNTGYQLDG-DNKTCIFIDVDWCLQDPSPCDQTCNST 219

Query: 365 QGRHQCLCEEGYILERGQH 383
            G+  C C +G+ L  G  
Sbjct: 218 DGKFTCGCFKGFQLNPGNR 162

 Score = 31.6 bits (70), Expect = 6.8,   Method: Compositional matrix adjust.
 Identities = 15/37 (40%), Positives = 21/37 (56%)
 Frame = -1

Query: 2023 CSNNPNACQQICLPVPGGMFSCACASGFKLSPDGRSC 2059
            C  +P+ C Q C    G  F+C C  GF+L+P  R+C
Sbjct: 263  CLQDPSPCDQTCNSTDG-KFTCGCFKGFQLNPGNRTC 156
>30893
          Length = 490

 Score = 44.3 bits (103), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 26/71 (36%), Positives = 38/71 (53%)
 Frame = +2

Query: 3113 INECQDSSISHCDHNCTDTITSFYCSCLPGYKLMSDKRTCVDIDECKETPQLCSQKCENV 3172
            INEC  +   +    CTD I  + C+C PGY+ ++ +    DIDEC   P L    C ++
Sbjct: 197  INECFSAPCQN-GATCTDLIGRYTCTCEPGYQGLNCE---YDIDECHNQPCLNGGTCHDL 364

Query: 3173 IGSYICKCAPG 3183
            + +Y C C PG
Sbjct: 365  VNTYKCSCPPG 397

 Score = 33.9 bits (76), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 19/57 (33%), Positives = 28/57 (49%)
 Frame = +2

Query: 3128 CTDTITSFYCSCLPGYKLMSDKRTCVDIDECKETPQLCSQKCENVIGSYICKCAPGY 3184
            C +T  +  C+C  G++    +    DI+EC   P      C ++IG Y C C PGY
Sbjct: 125  CHNTGNTHMCTCASGFEGSYCEN---DINECFSAPCQNGATCTDLIGRYTCTCEPGY 286
>03773
          Length = 1046

 Score = 43.5 bits (101), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 31/80 (38%), Positives = 44/80 (55%), Gaps = 7/80 (8%)
 Frame = +2

Query: 3113 INECQDSSISHCDHN---CTDTITSFYCSCLPGYKLMSDKRTCVDIDECKETPQL--CSQ 3167
            INEC  +S++ C+     C D+  SF C C  G+   S   +C D+DEC + P L  CS 
Sbjct: 647  INECLYASLNTCNMTTEICVDSDGSFGCECKSGFN--STSGSCTDVDECTD-PALNTCSD 817

Query: 3168 K--CENVIGSYICKCAPGYI 3185
            +  C N +GSY C+C   Y+
Sbjct: 818  REDCVNSVGSYTCQCKSTYV 877

 Score = 42.0 bits (97), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 27/89 (30%), Positives = 44/89 (49%), Gaps = 5/89 (5%)
 Frame = +2

Query: 3113 INECQDSSISHCD--HNCTDTITSFYCSCLPGYKLMSDKRTCVDIDECKETP-QLCSQK- 3168
            ++EC D +++ C    +C +++ S+ C C   Y L+     C D +EC ++    C+ K 
Sbjct: 776  VDECTDPALNTCSDREDCVNSVGSYTCQCKSTYVLV--NXVCTDFNECSDSSLNNCTSKE 949

Query: 3169 -CENVIGSYICKCAPGYIREPDGKSCRQN 3196
             C ++IG Y C C  GY R      C  N
Sbjct: 950  NCVDIIGGYRCDCKTGYARNTTTGLCSAN 1036

 Score = 35.8 bits (81), Expect = 0.39,   Method: Compositional matrix adjust.
 Identities = 22/53 (41%), Positives = 25/53 (47%), Gaps = 12/53 (22%)
 Frame = +2

Query: 4009 DINECEEFGICPQ----SCRNSKGSYECFCVDGFKSMS--------THYGERC 4049
            DINECE+   C       C N+ G Y C C DGF S          THYG +C
Sbjct: 248  DINECEDSATCASISNSHCNNTLGGYVCACDDGFSSSGGMCMPCDDTHYGTQC 406

 Score = 32.7 bits (73), Expect = 3.9,   Method: Compositional matrix adjust.
 Identities = 21/54 (38%), Positives = 29/54 (53%), Gaps = 4/54 (7%)
 Frame = +2

Query: 3985 SNGGFICSCRPGFKPSTLDKNSCQDINECEE--FGICP--QSCRNSKGSYECFC 4034
            S+G F C C+ GF  ++    SC D++EC +     C   + C NS GSY C C
Sbjct: 710  SDGSFGCECKSGFNSTS---GSCTDVDECTDPALNTCSDREDCVNSVGSYTCQC 862

 Score = 32.3 bits (72), Expect = 4.8,   Method: Compositional matrix adjust.
 Identities = 24/63 (38%), Positives = 32/63 (50%), Gaps = 6/63 (9%)
 Frame = +2

Query: 3986 NGGFICSCRPGF-KPSTLDKNSCQDINEC--EEFGICPQS---CRNSKGSYECFCVDGFK 4039
            +GG+ C C  G+ +PS  D   C +INEC       C  +   C +S GS+ C C  GF 
Sbjct: 578  DGGYSCDCVSGYERPSPSDN--CTNINECLYASLNTCNMTTEICVDSDGSFGCECKSGFN 751

Query: 4040 SMS 4042
            S S
Sbjct: 752  STS 760
>18708
          Length = 481

 Score = 42.7 bits (99), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 23/59 (38%), Positives = 32/59 (54%), Gaps = 6/59 (10%)
 Frame = -3

Query: 3134 SFYCSCLPGYKLMSDKRTCVDIDECKETPQLCSQK---CENVIGSYIC---KCAPGYIR 3186
            S+ C C  G++L  D R+C DIDEC+E    C Q+   C N  G Y C   +C  G+ +
Sbjct: 446  SYRCECPEGWRLKRDGRSCEDIDECQEKTAYCPQQDSICVNTRGHYKCPVVRCPQGFAK 270

 Score = 42.0 bits (97), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 20/50 (40%), Positives = 30/50 (60%), Gaps = 4/50 (8%)
 Frame = -3

Query: 1369 PFGATCVCPIGYQLANDTKTCEDVNEC-DIPGFCSQH---CVNMRGSFRC 1414
            P    C CP G++L  D ++CED++EC +   +C Q    CVN RG ++C
Sbjct: 452  PGSYRCECPEGWRLKRDGRSCEDIDECQEKTAYCPQQDSICVNTRGHYKC 303

 Score = 37.7 bits (86), Expect = 0.10,   Method: Compositional matrix adjust.
 Identities = 27/75 (36%), Positives = 39/75 (52%), Gaps = 8/75 (10%)
 Frame = -3

Query: 3977 CEQNCTQLSNGGFICSCRPGFKPSTLDKNSCQDINECEE-FGICPQS---CRNSKGSYEC 4032
            C +    +  G + C C  G++    D  SC+DI+EC+E    CPQ    C N++G Y+C
Sbjct: 479  CAEAGVSIRPGSYRCECPEGWR-LKRDGRSCEDIDECQEKTAYCPQQDSICVNTRGHYKC 303

Query: 4033 ---FCVDGF-KSMST 4043
                C  GF K+ ST
Sbjct: 302  PVVRCPQGFAKTAST 258
>26964
          Length = 387

 Score = 41.6 bits (96), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 19/37 (51%), Positives = 25/37 (67%)
 Frame = -1

Query: 183 CSQKEFQCGSGECILRAYVCDHDNDCEDNSDEHNCNY 219
           C   +FQC +G CIL+A +CD  +DC D SDE  C+Y
Sbjct: 117 CDADQFQCRNGACILQAKMCDGRSDCTDESDELECDY 7

 Score = 41.6 bits (96), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 18/39 (46%), Positives = 24/39 (61%)
 Frame = -1

Query: 3800 CHPEHFQCTSGHCVPKALACDGRADCLDASDESACPTRF 3838
            C  + FQC +G C+ +A  CDGR+DC D SDE  C  + 
Sbjct: 117  CDADQFQCRNGACILQAKMCDGRSDCTDESDELECDYKL 1

 Score = 39.7 bits (91), Expect = 0.026,   Method: Compositional matrix adjust.
 Identities = 19/37 (51%), Positives = 22/37 (59%)
 Frame = -1

Query: 2995 CSTGEFSCANGRCIRQSFRCDRRNDCGDYSDERGCSY 3031
            C   +F C NG CI Q+  CD R+DC D SDE  C Y
Sbjct: 117  CDADQFQCRNGACILQAKMCDGRSDCTDESDELECDY 7

 Score = 38.9 bits (89), Expect = 0.043,   Method: Compositional matrix adjust.
 Identities = 17/41 (41%), Positives = 23/41 (56%)
 Frame = -1

Query: 3925 PTHKPCTDTEYKCSNGNCVSQHYVCDNVDDCGDLSDETGCN 3965
            P H  C   +++C NG C+ Q  +CD   DC D SDE  C+
Sbjct: 132  PAHARCDADQFQCRNGACILQAKMCDGRSDCTDESDELECD 10

 Score = 38.5 bits (88), Expect = 0.062,   Method: Compositional matrix adjust.
 Identities = 18/32 (56%), Positives = 22/32 (68%)
 Frame = -1

Query: 2908 CSANQFHCDNGRCISSSWVCDGDNDCGDMSDE 2939
            C A+QF C NG CI  + +CDG +DC D SDE
Sbjct: 117  CDADQFQCRNGACILQAKMCDGRSDCTDESDE 22

 Score = 38.1 bits (87), Expect = 0.087,   Method: Compositional matrix adjust.
 Identities = 18/38 (47%), Positives = 24/38 (63%)
 Frame = -1

Query: 3030 SYPPCRDDQFTCQNGQCITKLYVCDEDNDCGDGSDEQE 3067
            ++  C  DQF C+NG CI +  +CD  +DC D SDE E
Sbjct: 129  AHARCDADQFQCRNGACILQAKMCDGRSDCTDESDELE 16

 Score = 37.7 bits (86), Expect = 0.096,   Method: Compositional matrix adjust.
 Identities = 17/40 (42%), Positives = 21/40 (52%)
 Frame = -1

Query: 1020 PPTQQCGSSSFPCNNGKCVPSIFRCDGVDDCHDNSDEHQC 1059
            P   +C +  F C NG C+     CDG  DC D SDE +C
Sbjct: 132  PAHARCDADQFQCRNGACILQAKMCDGRSDCTDESDELEC 13

 Score = 37.4 bits (85), Expect = 0.15,   Method: Compositional matrix adjust.
 Identities = 17/36 (47%), Positives = 20/36 (55%)
 Frame = -1

Query: 3551 PHRFCRLGQFQCRDGNCTSPQALCNARQDCADGSDE 3586
             H  C   QFQCR+G C     +C+ R DC D SDE
Sbjct: 129  AHARCDADQFQCRNGACILQAKMCDGRSDCTDESDE 22

 Score = 37.0 bits (84), Expect = 0.17,   Method: Compositional matrix adjust.
 Identities = 17/37 (45%), Positives = 21/37 (56%)
 Frame = -1

Query: 3839 PNGTYCPAAMFECKNHVCIQSFWICDGENDCVDGSDE 3875
            P    C A  F+C+N  CI    +CDG +DC D SDE
Sbjct: 132  PAHARCDADQFQCRNGACILQAKMCDGRSDCTDESDE 22

 Score = 37.0 bits (84), Expect = 0.21,   Method: Compositional matrix adjust.
 Identities = 16/35 (45%), Positives = 22/35 (62%)
 Frame = -1

Query: 28  CGSGNFRCDNGYCIPASWRCDGTRDCLDDTDEIGC 62
           C +  F+C NG CI  +  CDG  DC D++DE+ C
Sbjct: 117 CDADQFQCRNGACILQAKMCDGRSDCTDESDELEC 13

 Score = 36.6 bits (83), Expect = 0.23,   Method: Compositional matrix adjust.
 Identities = 17/35 (48%), Positives = 21/35 (60%)
 Frame = -1

Query: 1272 CSPSHFLCDNGNCIYNSWVCDGDNDCRDMSDEKDC 1306
            C    F C NG CI  + +CDG +DC D SDE +C
Sbjct: 117  CDADQFQCRNGACILQAKMCDGRSDCTDESDELEC 13

 Score = 34.7 bits (78), Expect = 0.84,   Method: Compositional matrix adjust.
 Identities = 17/35 (48%), Positives = 22/35 (62%)
 Frame = -1

Query: 3593 HHRCEANEWQCANKRCIPEYWQCDSVDDCLDNSDE 3627
            H RC+A+++QC N  CI +   CD   DC D SDE
Sbjct: 126  HARCDADQFQCRNGACILQAKMCDGRSDCTDESDE 22

 Score = 34.7 bits (78), Expect = 0.97,   Method: Compositional matrix adjust.
 Identities = 18/36 (50%), Positives = 21/36 (58%)
 Frame = -1

Query: 3633 ASRTCRPGQFKCNNGRCIPQSWKCDVDNDCGDYSDE 3668
            A   C   QF+C NG CI Q+  CD  +DC D SDE
Sbjct: 129  AHARCDADQFQCRNGACILQAKMCDGRSDCTDESDE 22

 Score = 34.7 bits (78), Expect = 0.99,   Method: Compositional matrix adjust.
 Identities = 16/35 (45%), Positives = 20/35 (57%)
 Frame = -1

Query: 3077 CPPHQFRCDNGHCIEMGTVCNHVDDCSDNSDEKGC 3111
            C   QF+C NG CI    +C+   DC+D SDE  C
Sbjct: 117  CDADQFQCRNGACILQAKMCDGRSDCTDESDELEC 13

 Score = 34.7 bits (78), Expect = 1.0,   Method: Compositional matrix adjust.
 Identities = 16/32 (50%), Positives = 19/32 (59%)
 Frame = -1

Query: 148 DQLTCANGACYNTSQKCDHKVDCRDSSDEANC 179
           DQ  C NGAC   ++ CD + DC D SDE  C
Sbjct: 108 DQFQCRNGACILQAKMCDGRSDCTDESDELEC 13

 Score = 34.7 bits (78), Expect = 1.0,   Method: Compositional matrix adjust.
 Identities = 17/39 (43%), Positives = 20/39 (51%)
 Frame = -1

Query: 1146 ASGTCHPTQFRCPDHRCISPLYVCDGDKDCVDGSDEAGC 1184
            A   C   QF+C +  CI    +CDG  DC D SDE  C
Sbjct: 129  AHARCDADQFQCRNGACILQAKMCDGRSDCTDESDELEC 13

 Score = 33.9 bits (76), Expect = 1.4,   Method: Compositional matrix adjust.
 Identities = 17/37 (45%), Positives = 19/37 (51%)
 Frame = -1

Query: 108 CSSQQLTCSNGQCVPIEYRCDHVSDCPDGSDERNCYY 144
           C + Q  C NG C+     CD  SDC D SDE  C Y
Sbjct: 117 CDADQFQCRNGACILQAKMCDGRSDCTDESDELECDY 7

 Score = 32.7 bits (73), Expect = 3.1,   Method: Compositional matrix adjust.
 Identities = 16/42 (38%), Positives = 21/42 (50%)
 Frame = -1

Query: 2738 AFHTCRSTAFTCANGRCVPYHYRCDFYNDCGDNSDEAGCLFR 2779
            A   C +  F C NG C+     CD  +DC D SDE  C ++
Sbjct: 129  AHARCDADQFQCRNGACILQAKMCDGRSDCTDESDELECDYK 4

 Score = 32.0 bits (71), Expect = 6.5,   Method: Compositional matrix adjust.
 Identities = 17/36 (47%), Positives = 21/36 (58%)
 Frame = -1

Query: 1188 CTSSQFKCADGSSCINSRYRCDGVYDCKDNSDEAGC 1223
            C + QF+C +G+ CI     CDG  DC D SDE  C
Sbjct: 117  CDADQFQCRNGA-CILQAKMCDGRSDCTDESDELEC 13

 Score = 31.6 bits (70), Expect = 8.3,   Method: Compositional matrix adjust.
 Identities = 14/30 (46%), Positives = 19/30 (63%)
 Frame = -1

Query: 3890 RFRCDNSRCIYGHQLCNGVDDCGDGSDEKE 3919
            +F+C N  CI   ++C+G  DC D SDE E
Sbjct: 105  QFQCRNGACILQAKMCDGRSDCTDESDELE 16
>14158
          Length = 668

 Score = 41.6 bits (96), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 36/104 (34%), Positives = 54/104 (51%), Gaps = 7/104 (6%)
 Frame = +3

Query: 3943 VSQHYVCDNVDD--CGDLSDETGCNLG-ENRTCAEKICEQ--NCTQLSNGGFICSCRPGF 3997
            VS+ YVCD  D    GDL     CN+  EN++CA+ +C+   +CT   N  F C+C PG+
Sbjct: 141  VSRGYVCDCADSNYSGDL-----CNINIENKSCADGLCQNPGSCTDDVNASFTCACAPGY 305

Query: 3998 KPSTLDKNSCQDINECEEFGICPQSCRN--SKGSYECFCVDGFK 4039
              S  +      IN C +      +C++  S  ++ C CV+GF 
Sbjct: 306  TGSLCES----PINYCVDLPCNNGTCQSNASLQNFTCECVEGFT 425
>22430
          Length = 497

 Score = 41.2 bits (95), Expect = 0.011,   Method: Compositional matrix adjust.
 Identities = 16/32 (50%), Positives = 22/32 (68%)
 Frame = +2

Query: 3760 ECTESEFRCADQQCIPSRWVCDQENDCGDNSD 3791
            +C + EFRCA+ +CI  R  CD  ++CGD SD
Sbjct: 215  DCNQEEFRCANDRCIDKRLKCDDYDNCGDQSD 310

 Score = 40.8 bits (94), Expect = 0.014,   Method: Compositional matrix adjust.
 Identities = 21/51 (41%), Positives = 27/51 (52%), Gaps = 2/51 (3%)
 Frame = +2

Query: 2735 TVCAFHT--CRSTAFTCANGRCVPYHYRCDFYNDCGDNSDEAGCLFRSCNS 2783
             + AFH   C    F CAN RC+    +CD Y++CGD SD   CL    N+
Sbjct: 191  VLTAFHAGDCNQEEFRCANDRCIDKRLKCDDYDNCGDQSD--ACLLSVGNA 337

 Score = 38.5 bits (88), Expect = 0.060,   Method: Compositional matrix adjust.
 Identities = 16/27 (59%), Positives = 18/27 (66%)
 Frame = +2

Query: 3726 DFRCGNHHCIPLRWKCDGIDDCGDNSD 3752
            +FRC N  CI  R KCD  D+CGD SD
Sbjct: 230  EFRCANDRCIDKRLKCDDYDNCGDQSD 310

 Score = 38.5 bits (88), Expect = 0.063,   Method: Compositional matrix adjust.
 Identities = 16/31 (51%), Positives = 21/31 (67%)
 Frame = +2

Query: 2995 CSTGEFSCANGRCIRQSFRCDRRNDCGDYSD 3025
            C+  EF CAN RCI +  +CD  ++CGD SD
Sbjct: 218  CNQEEFRCANDRCIDKRLKCDDYDNCGDQSD 310

 Score = 37.4 bits (85), Expect = 0.15,   Method: Compositional matrix adjust.
 Identities = 19/46 (41%), Positives = 25/46 (54%), Gaps = 2/46 (4%)
 Frame = +2

Query: 3583 GSDEDRVLCEHHR--CEANEWQCANKRCIPEYWQCDSVDDCLDNSD 3626
            G+    VL   H   C   E++CAN RCI +  +CD  D+C D SD
Sbjct: 173  GAGFSLVLTAFHAGDCNQEEFRCANDRCIDKRLKCDDYDNCGDQSD 310

 Score = 35.8 bits (81), Expect = 0.37,   Method: Compositional matrix adjust.
 Identities = 17/41 (41%), Positives = 23/41 (56%)
 Frame = +2

Query: 3637 CRPGQFKCNNGRCIPQSWKCDVDNDCGDYSDEPIHECMTAA 3677
            C   +F+C N RCI +  KCD  ++CGD SD  +     AA
Sbjct: 218  CNQEEFRCANDRCIDKRLKCDDYDNCGDQSDACLLSVGNAA 340

 Score = 35.4 bits (80), Expect = 0.55,   Method: Compositional matrix adjust.
 Identities = 14/38 (36%), Positives = 23/38 (60%)
 Frame = +2

Query: 3930 CTDTEYKCSNGNCVSQHYVCDNVDDCGDLSDETGCNLG 3967
            C   E++C+N  C+ +   CD+ D+CGD SD    ++G
Sbjct: 218  CNQEEFRCANDRCIDKRLKCDDYDNCGDQSDACLLSVG 331

 Score = 33.1 bits (74), Expect = 2.4,   Method: Compositional matrix adjust.
 Identities = 14/31 (45%), Positives = 20/31 (64%)
 Frame = +2

Query: 3034 CRDDQFTCQNGQCITKLYVCDEDNDCGDGSD 3064
            C  ++F C N +CI K   CD+ ++CGD SD
Sbjct: 218  CNQEEFRCANDRCIDKRLKCDDYDNCGDQSD 310

 Score = 33.1 bits (74), Expect = 2.8,   Method: Compositional matrix adjust.
 Identities = 14/31 (45%), Positives = 18/31 (58%)
 Frame = +2

Query: 2908 CSANQFHCDNGRCISSSWVCDGDNDCGDMSD 2938
            C+  +F C N RCI     CD  ++CGD SD
Sbjct: 218  CNQEEFRCANDRCIDKRLKCDDYDNCGDQSD 310

 Score = 32.0 bits (71), Expect = 6.7,   Method: Compositional matrix adjust.
 Identities = 14/28 (50%), Positives = 17/28 (60%)
 Frame = +2

Query: 3889 QRFRCDNSRCIYGHQLCNGVDDCGDGSD 3916
            + FRC N RCI     C+  D+CGD SD
Sbjct: 227  EEFRCANDRCIDKRLKCDDYDNCGDQSD 310
>18588
          Length = 453

 Score = 40.4 bits (93), Expect = 0.019,   Method: Compositional matrix adjust.
 Identities = 30/82 (36%), Positives = 43/82 (52%), Gaps = 5/82 (6%)
 Frame = -1

Query: 2869 EFQCVSPHRCIPSYWFCDGEADCVDSSDEPDTCGHSLNSCSANQFHCDN----GRCISSS 2924
            EF C++    +P  +  D   DC D +DEP T     ++C+   F+C+N    G  + SS
Sbjct: 315  EFTCITSGETVPWEFVNDDYCDCKDGTDEPGT-----SACTNGFFYCENRGYRGSNLISS 151

Query: 2925 WVCDGDNDCGDMSDE-DQRHHC 2945
             V DG  DC D SDE ++R  C
Sbjct: 150  RVNDGICDCCDGSDEFEERIKC 85

 Score = 33.9 bits (76), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 28/78 (35%), Positives = 34/78 (43%), Gaps = 5/78 (6%)
 Frame = -1

Query: 3803 EHFQC-TSGHCVPKALACDGRADCLDASDESACPTRFPNGTYCPAAMFECKNH----VCI 3857
            + F C TSG  VP     D   DC D +DE       P  + C    F C+N       +
Sbjct: 318  KEFTCITSGETVPWEFVNDDYCDCKDGTDE-------PGTSACTNGFFYCENRGYRGSNL 160

Query: 3858 QSFWICDGENDCVDGSDE 3875
             S  + DG  DC DGSDE
Sbjct: 159  ISSRVNDGICDCCDGSDE 106

 Score = 33.1 bits (74), Expect = 2.7,   Method: Compositional matrix adjust.
 Identities = 27/73 (36%), Positives = 34/73 (46%), Gaps = 5/73 (6%)
 Frame = -1

Query: 72  FLCPAEGTCIPSSWVCDQDKDCSDGADEQQNCPGTT-CSSQQLTCSN----GQCVPIEYR 126
           F C   G  +P  +V D   DC DG DE    PGT+ C++    C N    G  +     
Sbjct: 312 FTCITSGETVPWEFVNDDYCDCKDGTDE----PGTSACTNGFFYCENRGYRGSNLISSRV 145

Query: 127 CDHVSDCPDGSDE 139
            D + DC DGSDE
Sbjct: 144 NDGICDCCDGSDE 106

 Score = 32.7 bits (73), Expect = 3.5,   Method: Compositional matrix adjust.
 Identities = 26/66 (39%), Positives = 34/66 (51%), Gaps = 3/66 (4%)
 Frame = -1

Query: 37  NGYCIPASWRCDGTRDCLDDTDEIGCPPRSCGSGFFLCP---AEGTCIPSSWVCDQDKDC 93
           +G  +P  +  D   DC D TDE G    +C +GFF C      G+ + SS V D   DC
Sbjct: 297 SGETVPWEFVNDDYCDCKDGTDEPG--TSACTNGFFYCENRGYRGSNLISSRVNDGICDC 124

Query: 94  SDGADE 99
            DG+DE
Sbjct: 123 CDGSDE 106
>19898
          Length = 823

 Score = 39.7 bits (91), Expect = 0.029,   Method: Compositional matrix adjust.
 Identities = 24/64 (37%), Positives = 31/64 (48%), Gaps = 7/64 (10%)
 Frame = -2

Query: 86  VCDQ---DKDCSDGADEQQNCPGTT----CSSQQLTCSNGQCVPIEYRCDHVSDCPDGSD 138
            CDQ   +     GA  Q   PG+T    C   + TC +G C+     CD + DCPD SD
Sbjct: 348 TCDQFYLESRLQTGASTQAPRPGSTTPAGCPEGKHTCPSGLCIDANNVCDGIKDCPDNSD 169

Query: 139 ERNC 142
           E +C
Sbjct: 168 ENSC 157

 Score = 38.5 bits (88), Expect = 0.063,   Method: Compositional matrix adjust.
 Identities = 16/35 (45%), Positives = 21/35 (60%)
 Frame = -2

Query: 3077 CPPHQFRCDNGHCIEMGTVCNHVDDCSDNSDEKGC 3111
            CP  +  C +G CI+   VC+ + DC DNSDE  C
Sbjct: 261  CPEGKHTCPSGLCIDANNVCDGIKDCPDNSDENSC 157

 Score = 36.6 bits (83), Expect = 0.22,   Method: Compositional matrix adjust.
 Identities = 15/39 (38%), Positives = 25/39 (64%)
 Frame = -2

Query: 1308 TQPFHCPSSQWQCPGYSICVNLSALCDGVFDCPNGTDES 1346
            T P  CP  +  CP   +C++ + +CDG+ DCP+ +DE+
Sbjct: 276  TTPAGCPEGKHTCPS-GLCIDANNVCDGIKDCPDNSDEN 163

 Score = 36.6 bits (83), Expect = 0.25,   Method: Compositional matrix adjust.
 Identities = 17/32 (53%), Positives = 21/32 (65%)
 Frame = -2

Query: 272 CPGSGRCISMDKVCDGVPDCPEGEDENNATSG 303
           CP SG CI  + VCDG+ DCP+  DEN+   G
Sbjct: 240 CP-SGLCIDANNVCDGIKDCPDNSDENSCDGG 148

 Score = 36.2 bits (82), Expect = 0.33,   Method: Compositional matrix adjust.
 Identities = 18/34 (52%), Positives = 19/34 (55%)
 Frame = -2

Query: 3723 PSGDFRCGNHHCIPLRWKCDGIDDCGDNSDEESC 3756
            P G   C +  CI     CDGI DC DNSDE SC
Sbjct: 258  PEGKHTCPSGLCIDANNVCDGIKDCPDNSDENSC 157

 Score = 35.0 bits (79), Expect = 0.68,   Method: Compositional matrix adjust.
 Identities = 16/42 (38%), Positives = 24/42 (57%)
 Frame = -2

Query: 3926 THKPCTDTEYKCSNGNCVSQHYVCDNVDDCGDLSDETGCNLG 3967
            T   C + ++ C +G C+  + VCD + DC D SDE  C+ G
Sbjct: 273  TPAGCPEGKHTCPSGLCIDANNVCDGIKDCPDNSDENSCDGG 148

 Score = 35.0 bits (79), Expect = 0.72,   Method: Compositional matrix adjust.
 Identities = 18/39 (46%), Positives = 23/39 (58%)
 Frame = -2

Query: 183 CSQKEFQCGSGECILRAYVCDHDNDCEDNSDEHNCNYDT 221
           C + +  C SG CI    VCD   DC DNSDE++C+  T
Sbjct: 261 CPEGKHTCPSGLCIDANNVCDGIKDCPDNSDENSCDGGT 145

 Score = 34.7 bits (78), Expect = 0.85,   Method: Compositional matrix adjust.
 Identities = 16/35 (45%), Positives = 21/35 (60%)
 Frame = -2

Query: 28  CGSGNFRCDNGYCIPASWRCDGTRDCLDDTDEIGC 62
           C  G   C +G CI A+  CDG +DC D++DE  C
Sbjct: 261 CPEGKHTCPSGLCIDANNVCDGIKDCPDNSDENSC 157

 Score = 34.7 bits (78), Expect = 0.90,   Method: Compositional matrix adjust.
 Identities = 19/45 (42%), Positives = 22/45 (48%)
 Frame = -2

Query: 3755 SCVPRECTESEFRCADQQCIPSRWVCDQENDCGDNSDERDCEMKT 3799
            S  P  C E +  C    CI +  VCD   DC DNSDE  C+  T
Sbjct: 279  STTPAGCPEGKHTCPSGLCIDANNVCDGIKDCPDNSDENSCDGGT 145

 Score = 34.7 bits (78), Expect = 0.93,   Method: Compositional matrix adjust.
 Identities = 20/56 (35%), Positives = 26/56 (46%)
 Frame = -2

Query: 1004 KLQRDQMTCEGDPAREPPTQQCGSSSFPCNNGKCVPSIFRCDGVDDCHDNSDEHQC 1059
            +LQ    T    P    P   C      C +G C+ +   CDG+ DC DNSDE+ C
Sbjct: 321  RLQTGASTQAPRPGSTTPAG-CPEGKHTCPSGLCIDANNVCDGIKDCPDNSDENSC 157

 Score = 33.9 bits (76), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 17/35 (48%), Positives = 18/35 (51%)
 Frame = -2

Query: 1150 CHPTQFRCPDHRCISPLYVCDGDKDCVDGSDEAGC 1184
            C   +  CP   CI    VCDG KDC D SDE  C
Sbjct: 261  CPEGKHTCPSGLCIDANNVCDGIKDCPDNSDENSC 157

 Score = 32.3 bits (72), Expect = 4.0,   Method: Compositional matrix adjust.
 Identities = 17/39 (43%), Positives = 19/39 (48%)
 Frame = -2

Query: 1268 VPKTCSPSHFLCDNGNCIYNSWVCDGDNDCRDMSDEKDC 1306
             P  C      C +G CI  + VCDG  DC D SDE  C
Sbjct: 273  TPAGCPEGKHTCPSGLCIDANNVCDGIKDCPDNSDENSC 157

 Score = 32.3 bits (72), Expect = 4.8,   Method: Compositional matrix adjust.
 Identities = 16/36 (44%), Positives = 20/36 (55%)
 Frame = -2

Query: 1188 CTSSQFKCADGSSCINSRYRCDGVYDCKDNSDEAGC 1223
            C   +  C  G  CI++   CDG+ DC DNSDE  C
Sbjct: 261  CPEGKHTCPSGL-CIDANNVCDGIKDCPDNSDENSC 157

 Score = 32.3 bits (72), Expect = 5.2,   Method: Compositional matrix adjust.
 Identities = 20/44 (45%), Positives = 25/44 (56%)
 Frame = -2

Query: 64  PRSCGSGFFLCPAEGTCIPSSWVCDQDKDCSDGADEQQNCPGTT 107
           P  C  G   CP+ G CI ++ VCD  KDC D +DE  +C G T
Sbjct: 270 PAGCPEGKHTCPS-GLCIDANNVCDGIKDCPDNSDE-NSCDGGT 145

 Score = 31.6 bits (70), Expect = 7.0,   Method: Compositional matrix adjust.
 Identities = 14/32 (43%), Positives = 18/32 (56%)
 Frame = -2

Query: 3844 CPAAMFECKNHVCIQSFWICDGENDCVDGSDE 3875
            CP     C + +CI +  +CDG  DC D SDE
Sbjct: 261  CPEGKHTCPSGLCIDANNVCDGIKDCPDNSDE 166

 Score = 31.6 bits (70), Expect = 8.7,   Method: Compositional matrix adjust.
 Identities = 16/33 (48%), Positives = 22/33 (66%)
 Frame = -2

Query: 2786 EFTCSNGRCIPLSYVCNGINNCHDNDTSDEKNC 2818
            + TC +G CI  + VC+GI +C DN  SDE +C
Sbjct: 249  KHTCPSGLCIDANNVCDGIKDCPDN--SDENSC 157
>03572
          Length = 776

 Score = 35.4 bits (80), Expect = 0.55,   Method: Composition-based stats.
 Identities = 28/90 (31%), Positives = 41/90 (45%), Gaps = 10/90 (11%)
 Frame = -1

Query: 2478 NRRIYYSDFSNQTINSMAEDGSNRAVIARVSK-------PRAIVLDPCRGYMYWTDWGTN 2530
            N  I  SDF N ++     DGS       + +       P  + +DP  G++   DWG N
Sbjct: 452  NNDIIVSDFHNHSVKVFGSDGSFLFCFGSMGEGNGQFNAPTGVAVDP-NGHILVADWG-N 279

Query: 2531 AKIERATLGGNFRVPIVNTS---LVWPNGL 2557
            ++I+     G+F +  VNTS   L  P GL
Sbjct: 278  SRIQVFDANGSF-LSYVNTSAEPLYGPQGL 192
>03995
          Length = 944

 Score = 32.7 bits (73), Expect = 3.9,   Method: Compositional matrix adjust.
 Identities = 14/33 (42%), Positives = 20/33 (60%)
 Frame = -1

Query: 3165 CSQKCENVIGSYICKCAPGYIREPDGKSCRQNS 3197
            C   C N +GS+ C C+ G     DGKSC+++S
Sbjct: 944  CEGGCRNSVGSFACTCSAGSSLAEDGKSCKRSS 846
>13514
          Length = 1135

 Score = 32.3 bits (72), Expect = 4.1,   Method: Compositional matrix adjust.
 Identities = 22/58 (37%), Positives = 33/58 (56%), Gaps = 5/58 (8%)
 Frame = -2

Query: 3986 NGGFICSCRPGFKPS--TLDKNSCQDINE---CEEFGICPQSCRNSKGSYECFCVDGF 4038
            NG  IC+C+ G++ +  ++D N CQ+      CE  G    +C+N  GSY+C C  GF
Sbjct: 663  NGVAICTCQKGWRGADCSIDINECQESTTTVVCEHGG----TCQNLNGSYQCNCPTGF 502
>22230
          Length = 865

 Score = 31.6 bits (70), Expect = 7.0,   Method: Composition-based stats.
 Identities = 13/42 (30%), Positives = 22/42 (52%)
 Frame = +2

Query: 2928 DGDNDCGDMSDEDQRHHCELQNCSSTEFTCINSRPPNRRCIP 2969
            D   DCGD+++E+ +    LQ C+  +  C    P   +C+P
Sbjct: 458  DTTVDCGDITEEENKAFTFLQRCTIVQH*CFLEEPILVKCLP 583
>21089
          Length = 434

 Score = 31.6 bits (70), Expect = 7.9,   Method: Compositional matrix adjust.
 Identities = 14/33 (42%), Positives = 20/33 (60%), Gaps = 1/33 (3%)
 Frame = -3

Query: 3035 RDDQFTCQNG-QCITKLYVCDEDNDCGDGSDEQ 3066
            R D F C+N   C+++   CDE+  C DG+DE 
Sbjct: 369  RGDMFMCENKLMCVSQNLRCDEEPHCSDGTDEM 271
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|19527388|ref|NP_598911.1| otubain 1 [Mus musculus]
         (271 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

37910                                                                 137   5e-33
34682                                                                  27   6.4  
>37910
          Length = 1315

 Score =  137 bits (344), Expect = 5e-33,   Method: Compositional matrix adjust.
 Identities = 64/92 (69%), Positives = 72/92 (78%)
 Frame = -2

Query: 179  TSGYLQRESKFFEHFIEGGRTVKEFCQQEVEPMCKESDHIHIIALAQALSVSIQVEYMDR 238
             SG+LQ+E+ F+  FIEGGRT KEFC QEVEPM KESDHIHIIAL+ AL+  I VEYMDR
Sbjct: 1314 VSGHLQKEADFYASFIEGGRTPKEFCAQEVEPMGKESDHIHIIALSTALNTGIAVEYMDR 1135

Query: 239  GEGGTTNPHVFPEGSEPKVYLLYRPGHYDILY 270
            G   + N  VFPEG+ P V LLYRPGHYDILY
Sbjct: 1134 GGDNSCNQLVFPEGARPSVRLLYRPGHYDILY 1039
>34682
          Length = 1030

 Score = 27.3 bits (59), Expect = 6.4,   Method: Compositional matrix adjust.
 Identities = 14/28 (50%), Positives = 19/28 (67%)
 Frame = +2

Query: 122 KEDLVSQGFTEFTIEDFHNTFMDLIEQV 149
           KE L+SQGFT +T  DF N F+   E++
Sbjct: 383 KESLLSQGFTAWTKRDF-NQFIKANEEI 463
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|21536248|ref|NP_598755.1| glutathione S-transferase,
theta 3 [Mus musculus]
         (241 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

20209                                                                 137   5e-33
08076                                                                  89   2e-18
35754                                                                  36   0.014
32130                                                                  32   0.21 
01771                                                                  27   8.6  
>20209
          Length = 979

 Score =  137 bits (344), Expect = 5e-33,   Method: Compositional matrix adjust.
 Identities = 67/189 (35%), Positives = 111/189 (58%), Gaps = 1/189 (0%)
 Frame = -1

Query: 33  IELLKGQQYTDSFAQVNPLRKVPALKDGDFVLAESVAILLYLSRKYKAPDHWYPQDLQTR 92
           + L KG+ Y++ F +V+P R VPAL D  F L ES+AI+ Y+++     DHW P D + R
Sbjct: 976 VALRKGEHYSEDFVKVHPFRLVPALNDDGFRLTESIAIVDYIAKTRDVADHWLPADPKKR 797

Query: 93  ARVDEYLAWQHTALRSCCTRAMWQKMMFPVFLGQPVPPEMLASTLAELDGCLQVLEDKFL 152
           A+V+EYL W H   R          ++ P   G+PV  + + +    +   ++ +E+ FL
Sbjct: 796 AKVNEYLHWHHANTRLSSAMLFQHLLLIPRMKGEPVDQKQVKTFTKRVQTAIKGIENYFL 617

Query: 153 RNQAFLTGSHISVADLVAITELMHPVSAGC-KIFESRPKLAAWRQRVEAEVGESLFQEAH 211
           ++  F++   I+VAD+ A+ ELM   +    +++ES P + AW +RV+ E+G  LF +AH
Sbjct: 616 KDTPFISSDVITVADIFAVCELMQLYAVRQEELYESSPVVKAWVERVKKEIG-PLFDKAH 440

Query: 212 EVVLKAKDM 220
           +VV + +DM
Sbjct: 439 QVVYRVRDM 413
>08076
          Length = 914

 Score = 88.6 bits (218), Expect = 2e-18,   Method: Compositional matrix adjust.
 Identities = 45/136 (33%), Positives = 78/136 (57%), Gaps = 1/136 (0%)
 Frame = -2

Query: 86  PQDLQTRARVDEYLAWQHTALRSCCTRAMWQKMMFPVFLGQPVPPEMLASTLAELDGCLQ 145
           P D + RA+VDEYL W H   R          ++ P   G+PV  + + +    +   ++
Sbjct: 910 PADPKKRAKVDEYLHWHHANTRLSSAMLFQHLLLIPRMKGEPVDQKQVKTFTKRVQTAIK 731

Query: 146 VLEDKFLRNQAFLTGSHISVADLVAITELMHPVSAGC-KIFESRPKLAAWRQRVEAEVGE 204
            +E+ FL++  F++ + I+VAD+ A+ ELM   +    +++ES P + AW +RV+ E+G 
Sbjct: 730 GIENYFLKDTPFISSNVITVADIFAVCELMQLYAVRQEELYESSPVVKAWVERVKKEIG- 554

Query: 205 SLFQEAHEVVLKAKDM 220
            LF +AH+VV + +DM
Sbjct: 553 PLFDKAHQVVYRVRDM 506
>35754
          Length = 581

 Score = 35.8 bits (81), Expect = 0.014,   Method: Compositional matrix adjust.
 Identities = 37/150 (24%), Positives = 65/150 (43%), Gaps = 2/150 (1%)
 Frame = -2

Query: 53  KVPALKDGDFVLAESVAILLYLSRKYKAPDHWYPQDLQTRARVDEYLAWQHTALRSCCTR 112
            +P   DGD  L +S AIL Y++RK+    +   +     ARV E +       R+   R
Sbjct: 484 NLPYYIDGDIKLTQSNAILRYIARKH----NLMGETPLESARV-EMMLENAMDFRNGVVR 320

Query: 113 AMWQKMMFPVFLGQPVPPEMLASTLAELDGCLQVLEDKFLRNQAFLTGSHISVADLVAIT 172
            ++           P   ++L     ++   L    +K+L ++ +  G  ++VAD   + 
Sbjct: 319 MVY----------NPKYTDLLEEYKPKVKETLAGF-NKYLADKKWFAGDKVTVADF-HMY 176

Query: 173 ELM--HPVSAGCKIFESRPKLAAWRQRVEA 200
           EL+  H +  G  + +  PKL A+    EA
Sbjct: 175 ELLDQHRLMIGADVLKDYPKLTAFMAAFEA 86
>32130
          Length = 459

 Score = 32.0 bits (71), Expect = 0.21,   Method: Compositional matrix adjust.
 Identities = 25/92 (27%), Positives = 40/92 (43%), Gaps = 2/92 (2%)
 Frame = -3

Query: 5   LYLDLMSQPCRAVYIFAKKNGIPFQLRTIELLK--GQQYTDSFAQVNPLRKVPALKDGDF 62
           LY    S     V I     G+ +    + L+K  G+Q  + +  VNP+ +VP L     
Sbjct: 349 LYSYFRSTASWRVRIALAMKGVDYDYAPVHLVKDGGEQNKEEYKSVNPMGQVPTLVIDGL 170

Query: 63  VLAESVAILLYLSRKYKAPDHWYPQDLQTRAR 94
            L +S+ I+ YL    +      P+D   RA+
Sbjct: 169 TLTQSMPIIEYLEETRQG-TPILPKDAGKRAQ 77
>01771
          Length = 1615

 Score = 26.6 bits (57), Expect = 8.6,   Method: Compositional matrix adjust.
 Identities = 17/61 (27%), Positives = 27/61 (44%)
 Frame = -1

Query: 162 HISVADLVAITELMHPVSAGCKIFESRPKLAAWRQRVEAEVGESLFQEAHEVVLKAKDMP 221
           H+ VA + ++ + +  V A  +I  S   +  W+ R+    G S F      VL    MP
Sbjct: 313 HMMVARIASVAKTLPWVLAN*RIMGSSVVVTLWKMRLIRFNGFSFFVVTRS*VLSYISMP 134

Query: 222 P 222
           P
Sbjct: 133 P 131
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6755212|ref|NP_035319.1| proteasome (prosome,
macropain) 28 subunit, alpha [Mus musculus]
         (249 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

01374                                                                 137   5e-33
27157                                                                 130   5e-31
12817                                                                  42   3e-04
>01374
          Length = 1519

 Score =  137 bits (344), Expect = 5e-33,   Method: Compositional matrix adjust.
 Identities = 81/243 (33%), Positives = 122/243 (50%), Gaps = 6/243 (2%)
 Frame = +3

Query: 13  KVDVFREDLCSKTENLLGSYFPKKISELDAFLKEPALNEANLSNLKAPLDIPVPDPVXXX 72
           KV  F E+   +TE L+   FP+K+ +++   ++    + N  ++ A ++IPVP+P    
Sbjct: 120 KVSEFIENFKKQTEALVTDIFPQKVLDIEEIYQKMIAEKTN--DVHAAINIPVPEPALLK 293

Query: 73  XXXXXXXXXXXXXXXXXXXXXXXXXXP------PCGPVNCNEKIVVLLQRLKPEIKDVTE 126
                                            P G V  N  I    + +KP I D+ E
Sbjct: 294 EDQEEPAGKKRKLDANGSDSLSPAPSGTPVLVFPNGKVPYNTYIRNWAEDIKPLITDLME 473

Query: 127 QLNLVTTWLQLQIPRIEDGNNFGVAVQEKVFELMTNLHTKLEGFHTQISKYFSERGDAVA 186
             N+V  W+   IP+IEDGNNFGV++QE        + T+   +  Q+S+Y+  R   ++
Sbjct: 474 HANMVKMWISFLIPKIEDGNNFGVSIQEDTMAEARQVETESATYLDQLSRYYISRAKIIS 653

Query: 187 KAAKQPHVGDYRQLVHELDEAEYQEIRLMVMEIRNAYAVLYDIILKNFEKLKKPRGETKG 246
           + AK PHV DYRQ + ELDE +   +RL + E+RN YA L+DII KN EK+KKPR     
Sbjct: 654 RIAKYPHVEDYRQSIRELDEKQIVCLRLTLCEMRNHYASLHDIIHKNMEKIKKPRSGNAE 833

Query: 247 MIY 249
            +Y
Sbjct: 834 NLY 842
>27157
          Length = 381

 Score =  130 bits (327), Expect = 5e-31,   Method: Compositional matrix adjust.
 Identities = 59/126 (46%), Positives = 81/126 (64%)
 Frame = +1

Query: 124 VTEQLNLVTTWLQLQIPRIEDGNNFGVAVQEKVFELMTNLHTKLEGFHTQISKYFSERGD 183
           + E  NL+  W+   IP+IEDGNNFGV++QE     +  + ++   F  QIS+YF  R  
Sbjct: 1   LVEDSNLLKMWISFMIPKIEDGNNFGVSIQEDTLAEIQTVESEAAAFFDQISRYFLTRAK 180

Query: 184 AVAKAAKQPHVGDYRQLVHELDEAEYQEIRLMVMEIRNAYAVLYDIILKNFEKLKKPRGE 243
            V+K AK PH+ DYR+ V ELDE EY  + L+V E+RN Y+ L+DI++KN EKLKKPR  
Sbjct: 181 VVSKVAKYPHIDDYRRAVVELDEKEYLSLWLVVCEVRNRYSSLHDIVIKNLEKLKKPRSS 360

Query: 244 TKGMIY 249
               +Y
Sbjct: 361 NTESLY 378
>12817
          Length = 422

 Score = 42.0 bits (97), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 23/58 (39%), Positives = 33/58 (56%)
 Frame = +1

Query: 12  AKVDVFREDLCSKTENLLGSYFPKKISELDAFLKEPALNEANLSNLKAPLDIPVPDPV 69
           +KV  ++  L +K E L+   FP+KI EL+  L  P  NE N S +   L+IPV  P+
Sbjct: 121 SKVADYKVSLITKAEILITKGFPEKIVELNELLATPMFNERNFSEVHQDLNIPVMAPI 294
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|22122585|ref|NP_666195.1| splicing factor,
arginine/serine-rich 7 [Mus musculus]
         (238 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

02347                                                                 136   6e-33
20169                                                                 103   7e-23
02809                                                                  94   7e-20
01065                                                                  69   2e-12
23720                                                                  60   9e-10
04988                                                                  60   1e-09
00738                                                                  58   3e-09
00029                                                                  52   2e-07
16427                                                                  51   3e-07
29364                                                                  51   5e-07
03059                                                                  49   2e-06
31310                                                                  45   3e-05
17681                                                                  43   1e-04
17775                                                                  41   4e-04
02140                                                                  40   0.001
11579                                                                  39   0.001
24794                                                                  39   0.002
15503                                                                  36   0.013
25950                                                                  36   0.014
11126                                                                  35   0.019
12350                                                                  35   0.024
02735                                                                  33   0.14 
11687                                                                  33   0.14 
12506                                                                  32   0.22 
25632                                                                  30   0.79 
38833                                                                  28   4.0  
00781                                                                  28   4.6  
12593                                                                  27   8.2  
19824                                                                  27   8.9  
>02347
          Length = 928

 Score =  136 bits (343), Expect = 6e-33,   Method: Compositional matrix adjust.
 Identities = 72/125 (57%), Positives = 84/125 (67%), Gaps = 5/125 (4%)
 Frame = -3

Query: 1   MSRYGRYGGETKVYVGNLGTGAGKGELERAFSYYGPLRTVWIARNPPGFAFVEFEDPRDA 60
           MSRYG    E K+YVG+L   A + E+ERAF+YYG LR VW+ARNPPGFAFVEFED RDA
Sbjct: 773 MSRYGS-SVEGKIYVGDLPPDASEKEVERAFNYYGHLRNVWVARNPPGFAFVEFEDTRDA 597

Query: 61  EDAVRGLDGKVICGSRVRVELSTG-----MXXXXXXXXXXXXXXXXXXXXCYECGEKGHY 115
           +DAVR LDG V+CG+RVRVE STG     M                    CYECG++GHY
Sbjct: 596 DDAVRALDGTVVCGNRVRVEHSTGRVRPKMGGGSSRGRGPPRRAFRPEDRCYECGDRGHY 417

Query: 116 AYDCH 120
           AYDC+
Sbjct: 416 AYDCY 402
>20169
          Length = 1364

 Score =  103 bits (257), Expect = 7e-23,   Method: Compositional matrix adjust.
 Identities = 51/83 (61%), Positives = 59/83 (71%)
 Frame = -1

Query: 1    MSRYGRYGGETKVYVGNLGTGAGKGELERAFSYYGPLRTVWIARNPPGFAFVEFEDPRDA 60
            MSR+  +  + KVYVG LG G  K ELE  F+ YGPL+ VW+AR P GFAFVEFED RDA
Sbjct: 1100 MSRHRDFSLDCKVYVGELGHGCAKQELEDKFAKYGPLKNVWVARRPAGFAFVEFEDNRDA 921

Query: 61   EDAVRGLDGKVICGSRVRVELST 83
            EDAV+ LDG  I G R RVE+S 
Sbjct: 920  EDAVQALDGARINGRRARVEMSN 852
>02809
          Length = 1475

 Score = 93.6 bits (231), Expect = 7e-20,   Method: Compositional matrix adjust.
 Identities = 44/69 (63%), Positives = 51/69 (73%)
 Frame = -1

Query: 1    MSRYGRYGGETKVYVGNLGTGAGKGELERAFSYYGPLRTVWIARNPPGFAFVEFEDPRDA 60
            MSR+  +  + KVYVG LG G  K ELE  F+ YGPL+ VW+AR P GFAFVEFED RDA
Sbjct: 1364 MSRHRDFSLDCKVYVGELGHGCAKQELEDKFAKYGPLKNVWVARRPAGFAFVEFEDNRDA 1185

Query: 61   EDAVRGLDG 69
            EDAV+ LDG
Sbjct: 1184 EDAVQALDG 1158
>01065
          Length = 1033

 Score = 68.9 bits (167), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 34/109 (31%), Positives = 54/109 (49%)
 Frame = +2

Query: 11  TKVYVGNLGTGAGKGELERAFSYYGPLRTVWIARNPPGFAFVEFEDPRDAEDAVRGLDGK 70
           T+++VG+L +     E+   F  +G +  +W+ R  P  AFV +    DAE A+R +DG+
Sbjct: 14  TRIHVGSLSSSTSTREIREEFKRFGDIIDLWMPRTQPTIAFVVYRYEEDAEKAIRRMDGE 193

Query: 71  VICGSRVRVELSTGMXXXXXXXXXXXXXXXXXXXXCYECGEKGHYAYDC 119
            + G RVRV L+                       CY+CG +GH++ DC
Sbjct: 194 SMHGRRVRVSLA------RPRSQGVRGGSFNPNLRCYQCGRRGHFSRDC 322
>23720
          Length = 739

 Score = 59.7 bits (143), Expect = 9e-10,   Method: Compositional matrix adjust.
 Identities = 33/74 (44%), Positives = 47/74 (63%)
 Frame = -1

Query: 11  TKVYVGNLGTGAGKGELERAFSYYGPLRTVWIARNPPGFAFVEFEDPRDAEDAVRGLDGK 70
           T+VY+G L   A + ++ER F  YG +  + +     G+ FVEFED RDA+DAV  L+GK
Sbjct: 685 TRVYIGRLPYQAREKDIERFFRGYGRVNDIMLKN---GYGFVEFEDFRDADDAVYELNGK 515

Query: 71  VICGSRVRVELSTG 84
            +CG RV +E + G
Sbjct: 514 DLCGERVIIEHARG 473
>04988
          Length = 705

 Score = 59.7 bits (143), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 33/74 (44%), Positives = 47/74 (63%)
 Frame = -3

Query: 11  TKVYVGNLGTGAGKGELERAFSYYGPLRTVWIARNPPGFAFVEFEDPRDAEDAVRGLDGK 70
           T+VY+G L   A + ++ER F  YG +  + +     G+ FVEFED RDA+DAV  L+GK
Sbjct: 652 TRVYIGRLPYQAREKDIERFFRGYGRVNDIMLKN---GYGFVEFEDFRDADDAVYELNGK 482

Query: 71  VICGSRVRVELSTG 84
            +CG RV +E + G
Sbjct: 481 DLCGERVIIEHARG 440
>00738
          Length = 1559

 Score = 58.2 bits (139), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 31/103 (30%), Positives = 49/103 (47%)
 Frame = -2

Query: 11   TKVYVGNLGTGAGKGELERAFSYYGPLRTVWIARNPPGFAFVEFEDPRDAEDAVRGLDGK 70
            T+++VG+L +     E+   F  +G +  +W+ R  P  AFV +    DAE A+R +DG+
Sbjct: 1267 TRIHVGSLSSSTSTREIREEFKRFGDIIDLWMPRTQPTIAFVVYRYEEDAEKAIRRMDGE 1088

Query: 71   VICGSRVRVELSTGMXXXXXXXXXXXXXXXXXXXXCYECGEKG 113
             + G RVRV L+                       CY+CG +G
Sbjct: 1087 SMHGRRVRVSLA------RPRSQGVRGGSFNPNLRCYQCGRRG 977
>00029
          Length = 2204

 Score = 52.0 bits (123), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 30/79 (37%), Positives = 42/79 (53%)
 Frame = -3

Query: 6    RYGGETKVYVGNLGTGAGKGELERAFSYYGPLRTVWIARNPPGFAFVEFEDPRDAEDAVR 65
            +Y    K+++GNLG      EL   F  YG +    + +N   F FV      +A+DA+ 
Sbjct: 2151 KYNMTIKIFIGNLGDDTDPEELRALFEKYGSVAECDVLKN---FGFVHMVKKGEADDAIS 1981

Query: 66   GLDGKVICGSRVRVELSTG 84
             L+G  I G R+RVELSTG
Sbjct: 1980 NLNGYNIGGQRMRVELSTG 1924
>16427
          Length = 1313

 Score = 51.2 bits (121), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 29/74 (39%), Positives = 43/74 (58%), Gaps = 5/74 (6%)
 Frame = +1

Query: 12  KVYVGNLGTGAGKGELERAFSYYGPLRTVWIARN-----PPGFAFVEFEDPRDAEDAVRG 66
           K++VG L     +  LER FS +G +    + R+       GF FV +E+P DAE+AV+ 
Sbjct: 139 KLFVGGLAEEIDEKVLEREFSKFGRITESMVIRDKVRQVSRGFGFVTYENPMDAEEAVKH 318

Query: 67  LDGKVICGSRVRVE 80
           +DGK I G ++ VE
Sbjct: 319 MDGKEILGKKLHVE 360
>29364
          Length = 1126

 Score = 50.8 bits (120), Expect = 5e-07,   Method: Compositional matrix adjust.
 Identities = 30/60 (50%), Positives = 37/60 (61%)
 Frame = +1

Query: 26 ELERAFSYYGPLRTVWIARNPPGFAFVEFEDPRDAEDAVRGLDGKVICGSRVRVELSTGM 85
          +LER F  YG  R + I     G+ FVEFED RDA+DAV  L+GK + G RV VE + G 
Sbjct: 13 DLERFFKGYGRTRDILIKN---GYGFVEFEDYRDADDAVYELNGKELLGERVVVEPARGT 183
>03059
          Length = 1154

 Score = 48.9 bits (115), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 26/73 (35%), Positives = 40/73 (54%), Gaps = 6/73 (8%)
 Frame = -2

Query: 11  TKVYVGNLGTGAGKGELERAFSYYGPLRTVWIARN------PPGFAFVEFEDPRDAEDAV 64
           TKV+VG L     K  ++  FS YG ++ + +  +        G A+VE+E+P DAE AV
Sbjct: 670 TKVHVGRLTRNVNKDHIQEIFSLYGTIKFIDLPNDRIHPNTSKGHAYVEYENPEDAEKAV 491

Query: 65  RGLDGKVICGSRV 77
           + +DG  I G  +
Sbjct: 490 KYMDGGQIDGQEI 452
>31310
          Length = 469

 Score = 45.1 bits (105), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 21/79 (26%), Positives = 48/79 (60%), Gaps = 5/79 (6%)
 Frame = -3

Query: 12  KVYVGNLGTGAGKGELERAFSYYGPLRTVWIARNP-----PGFAFVEFEDPRDAEDAVRG 66
           ++YVG++     +  +++AF  +GP+++V ++ +P      GF+F+E++ P  A+ A+  
Sbjct: 320 RIYVGSINFEIREDTIKQAFLPFGPIKSVNLSWDPITNKHKGFSFIEYDVPEAAQLALEQ 141

Query: 67  LDGKVICGSRVRVELSTGM 85
           ++G +I G  ++V   + M
Sbjct: 140 MNGVMIGGRNIKVGRPSNM 84
>17681
          Length = 964

 Score = 42.7 bits (99), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 23/76 (30%), Positives = 39/76 (51%), Gaps = 5/76 (6%)
 Frame = +2

Query: 13  VYVGNLGTGAGKGELERAFSYYGPLRTVWIARNP-----PGFAFVEFEDPRDAEDAVRGL 67
           ++VG+L        L  AF+ +G +    I R+P      G+AFV F    +AE+A++ +
Sbjct: 38  IFVGDLSPEIETETLREAFAPFGEISNCRIVRDPQTMKSKGYAFVSFVKKAEAENAIQAM 217

Query: 68  DGKVICGSRVRVELST 83
           +G+ I    +R   ST
Sbjct: 218 NGQWIGSRSIRTNWST 265
>17775
          Length = 1282

 Score = 40.8 bits (94), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 23/75 (30%), Positives = 38/75 (50%), Gaps = 5/75 (6%)
 Frame = -2

Query: 13   VYVGNLGTGAGKGELERAFSYYGPLRTV-----WIARNPPGFAFVEFEDPRDAEDAVRGL 67
            +YVG+L     +  L   FS  GP+ ++      I R   G+A+V F+ P DAE A+  +
Sbjct: 1188 LYVGDLHPDVTEAMLFEKFSTAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDTM 1009

Query: 68   DGKVICGSRVRVELS 82
            +   + G  +R+  S
Sbjct: 1008 NFDTVKGRPIRIMWS 964
>02140
          Length = 1796

 Score = 39.7 bits (91), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 23/78 (29%), Positives = 38/78 (48%), Gaps = 5/78 (6%)
 Frame = +3

Query: 13  VYVGNLGTGAGKGELERAFSYYGPLRTVWIARNPPG-----FAFVEFEDPRDAEDAVRGL 67
           ++V  L       +LE  FS +GP+ +  + R+        +AFVEFE P   E+A   +
Sbjct: 807 LFVCKLNPVTTDEDLEMIFSRFGPITSCEVIRDHKTKESLQYAFVEFEKPEHCENAYFKM 986

Query: 68  DGKVICGSRVRVELSTGM 85
           D  +I   R+ V+ S  +
Sbjct: 987 DNVLIDDRRIHVDFSQSV 1040
>11579
          Length = 1307

 Score = 39.3 bits (90), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 18/35 (51%), Positives = 25/35 (71%)
 Frame = +3

Query: 48 GFAFVEFEDPRDAEDAVRGLDGKVICGSRVRVELS 82
          GFAFV F D RDAEDA+  +DG ++ G  VR +++
Sbjct: 9  GFAFVRFYDRRDAEDAMDSMDGALLDGREVRCQMA 113
>24794
          Length = 622

 Score = 38.5 bits (88), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 22/69 (31%), Positives = 31/69 (44%)
 Frame = -2

Query: 47  PGFAFVEFEDPRDAEDAVRGLDGKVICGSRVRVELSTGMXXXXXXXXXXXXXXXXXXXXC 106
           P   FV +    DAE A+R +DG+ + G RVRV L+                       C
Sbjct: 501 PPLLFVVYRYEEDAEKAIRRMDGESMHGRRVRVSLAR------PRSQGVRGGSFNPNLRC 340

Query: 107 YECGEKGHY 115
           Y+CG +GH+
Sbjct: 339 YQCGRRGHF 313
>15503
          Length = 570

 Score = 36.2 bits (82), Expect = 0.013,   Method: Compositional matrix adjust.
 Identities = 22/64 (34%), Positives = 31/64 (48%), Gaps = 2/64 (3%)
 Frame = +1

Query: 13  VYVGNLGTGAGKGELERAFSYYGPLRTVWIARNP--PGFAFVEFEDPRDAEDAVRGLDGK 70
           +YV NL       E+   F  YG +R + +   P   G AFV +ED  DA++A   L G 
Sbjct: 154 LYVKNLPYKITAEEMYDIFGKYGAIRQIRVGNTPETKGTAFVVYEDIFDAKNACDHLSGF 333

Query: 71  VICG 74
            +C 
Sbjct: 334 NVCN 345
>25950
          Length = 417

 Score = 35.8 bits (81), Expect = 0.014,   Method: Compositional matrix adjust.
 Identities = 31/83 (37%), Positives = 37/83 (44%), Gaps = 12/83 (14%)
 Frame = -2

Query: 13  VYVGNLGTGAGKGELERAFSYYGPLRTVWIARN-----PPGFAFVEFEDPRDAEDAV--- 64
           VYVGN+  GA   ELE  F   G +  V I  N     P GFA++EF      E A+   
Sbjct: 275 VYVGNVDYGASAEELEAHFHGCGTINRVTILCNKADGHPKGFAYIEFGSKEYVETALAMN 96

Query: 65  ----RGLDGKVICGSRVRVELST 83
               RG   KV+     R  LST
Sbjct: 95  ETLFRGRQIKVMTKRTNRPGLST 27
>11126
          Length = 1061

 Score = 35.4 bits (80), Expect = 0.019,   Method: Compositional matrix adjust.
 Identities = 22/49 (44%), Positives = 28/49 (57%), Gaps = 5/49 (10%)
 Frame = -3

Query: 13  VYVGNLGTGAGKGELERAFSYYGPLRTVWI-----ARNPPGFAFVEFED 56
           VYVGN+  GA   ELE+ F   G +  V I     + +P GFA+VEF D
Sbjct: 624 VYVGNVDYGATAEELEQHFHGCGSVNRVTILCDKYSGHPKGFAYVEFAD 478
>12350
          Length = 975

 Score = 35.0 bits (79), Expect = 0.024,   Method: Compositional matrix adjust.
 Identities = 23/69 (33%), Positives = 36/69 (52%)
 Frame = -2

Query: 12  KVYVGNLGTGAGKGELERAFSYYGPLRTVWIARNPPGFAFVEFEDPRDAEDAVRGLDGKV 71
           K++VG         +L + FS +G +  V+I R    FAFV F DP  A+ ++ G D  +
Sbjct: 359 KIFVGRCTDDMTADDLRQFFSKFGEVVDVFIPRPFRAFAFVSFADPEVAQ-SLYGED-HI 186

Query: 72  ICGSRVRVE 80
           I G+ V + 
Sbjct: 185 IKGASVHIS 159
>02735
          Length = 970

 Score = 32.7 bits (73), Expect = 0.14,   Method: Compositional matrix adjust.
 Identities = 12/15 (80%), Positives = 15/15 (100%)
 Frame = -1

Query: 106 CYECGEKGHYAYDCH 120
           CYECG++GHYAYDC+
Sbjct: 904 CYECGDRGHYAYDCY 860
>11687
          Length = 676

 Score = 32.7 bits (73), Expect = 0.14,   Method: Compositional matrix adjust.
 Identities = 19/61 (31%), Positives = 29/61 (47%), Gaps = 5/61 (8%)
 Frame = +3

Query: 12  KVYVGNLGTGAGKGELERAFSYYGPLRTVWIARN-----PPGFAFVEFEDPRDAEDAVRG 66
           K++VG +     + EL + F  YGP+ ++ I R+       G  FV F   + A DA   
Sbjct: 153 KMFVGQIPRNMDENELRKMFEDYGPVHSLNILRDKNTGQSKGCCFVTFFTRKAALDAQNA 332

Query: 67  L 67
           L
Sbjct: 333 L 335
>12506
          Length = 1056

 Score = 32.0 bits (71), Expect = 0.22,   Method: Compositional matrix adjust.
 Identities = 15/38 (39%), Positives = 22/38 (57%)
 Frame = -3

Query: 48  GFAFVEFEDPRDAEDAVRGLDGKVICGSRVRVELSTGM 85
           GFAF+EFE   DA  A+  ++   + G  +RV L+  M
Sbjct: 937 GFAFIEFELAEDAAAAIDNMNESELFGRTIRVNLAKPM 824
>25632
          Length = 864

 Score = 30.0 bits (66), Expect = 0.79,   Method: Compositional matrix adjust.
 Identities = 15/37 (40%), Positives = 20/37 (54%)
 Frame = -2

Query: 48  GFAFVEFEDPRDAEDAVRGLDGKVICGSRVRVELSTG 84
            + FV      +A  A+  L+G  I G R+RVELST 
Sbjct: 665 NYGFVHMPTKSEASAAITNLNGYNIKGQRMRVELSTN 555
>38833
          Length = 754

 Score = 27.7 bits (60), Expect = 4.0,   Method: Compositional matrix adjust.
 Identities = 9/15 (60%), Positives = 9/15 (60%)
 Frame = -2

Query: 106 CYECGEKGHYAYDCH 120
           CY CG   H A DCH
Sbjct: 288 CYNCGSLAHKAADCH 244
>00781
          Length = 3170

 Score = 27.7 bits (60), Expect = 4.6,   Method: Compositional matrix adjust.
 Identities = 20/61 (32%), Positives = 29/61 (47%), Gaps = 5/61 (8%)
 Frame = -1

Query: 13   VYVGNLGTGAGKGELERAFSYYGPLRTVWI-----ARNPPGFAFVEFEDPRDAEDAVRGL 67
            VYV        +  + R FS  G +  V +      R   G+AFVEF+ P +A  AV+ L
Sbjct: 2714 VYVEGFHKFTSREWISRMFSKCGTVTYVSLPCFKTTREIKGYAFVEFQSPEEAVKAVQML 2535

Query: 68   D 68
            +
Sbjct: 2534 N 2532
>12593
          Length = 462

 Score = 26.9 bits (58), Expect = 8.2,   Method: Compositional matrix adjust.
 Identities = 10/17 (58%), Positives = 14/17 (82%)
 Frame = +2

Query: 48  GFAFVEFEDPRDAEDAV 64
           GFA+VEFEDP   ++A+
Sbjct: 128 GFAYVEFEDPDSLQEAL 178
>19824
          Length = 724

 Score = 26.6 bits (57), Expect = 8.9,   Method: Compositional matrix adjust.
 Identities = 23/72 (31%), Positives = 31/72 (43%)
 Frame = +1

Query: 48  GFAFVEFEDPRDAEDAVRGLDGKVICGSRVRVELSTGMXXXXXXXXXXXXXXXXXXXXCY 107
            F F  FED  +A+ A   L+G    GS +RVE+S                       CY
Sbjct: 34  NFGFAHFEDANEAKAAADALNGFNYNGSDLRVEISHSK--------VRQRPGMGNREGCY 189

Query: 108 ECGEKGHYAYDC 119
            CG+ GH++ DC
Sbjct: 190 RCGKDGHWSKDC 225
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|27369613|ref|NP_766044.1| endo/exonuclease (5'-3'),
endonuclease G-like precursor [Mus musculus]
         (368 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

08834                                                                 137   6e-33
>08834
          Length = 1164

 Score =  137 bits (345), Expect = 6e-33,   Method: Compositional matrix adjust.
 Identities = 70/178 (39%), Positives = 103/178 (57%), Gaps = 1/178 (0%)
 Frame = -2

Query: 110  KHCKFKPDPSVPSAFSALNEDYIGSGWSRGHMAPAGNNKFSSEAMAETFYLSNIVPQ-NF 168
            +  +FK D SV   F A N DY GS + RGH+A A N++ S +AM +TF LSNI PQ   
Sbjct: 1163 RKSQFKEDGSVHRYFRATNADYKGSSYDRGHLAAASNHRHSQKAMDQTFLLSNIAPQVGI 984

Query: 169  DNNSGYWNRIEMYCRELTERFEDVWIVSGPLTLPHTRNDGTKTVSYQVIGEDNVAVPSHL 228
              N G WN +E Y R L  R   V++ +GPL LP    DG + V Y+VIG +NVAVP+H 
Sbjct: 983  GFNRGAWNGLEKYTRALARRNRCVYVCTGPLYLPRKEEDGKRYVKYEVIGTNNVAVPTHF 804

Query: 229  YKVILARRSPESTEPLALGAFVVPNKAIGFQSQLSEFQVSLHDLEKMSGLVFFPRLDR 286
            +KV++        E   + +FV+PN+ +  + QL  +   +  +E+ +G + F ++ R
Sbjct: 803  FKVLVVEDPSGQYE---MKSFVLPNQPLSDKVQLKAYLYPIEAIERAAGFLLFDKIPR 639
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|85677508|ref|NP_001034258.1| eukaryotic translation
initiation factor 4E member 2 isoform 2 [Mus musculus]
         (240 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

04602                                                                 136   7e-33
01293                                                                 125   2e-29
18848                                                                  54   7e-08
00649                                                                  28   4.5  
>04602
          Length = 888

 Score =  136 bits (343), Expect = 7e-33,   Method: Compositional matrix adjust.
 Identities = 62/73 (84%), Positives = 70/73 (95%)
 Frame = +3

Query: 145 NLILAMLGEQFMVGEEICGAVVSVRFQEDIISIWNKTASDQATTARIRDTLRRVLNLPPN 204
           NLILAMLGEQFMVGEEICGAVVSVRFQ+DI+++WN+TASDQATT RIRDTL+RVL+LP N
Sbjct: 3   NLILAMLGEQFMVGEEICGAVVSVRFQDDILALWNRTASDQATTTRIRDTLKRVLHLPAN 182

Query: 205 TIMEYKTHTDSIK 217
           TIMEYKTH DS+K
Sbjct: 183 TIMEYKTHNDSLK 221
>01293
          Length = 1593

 Score =  125 bits (314), Expect = 2e-29,   Method: Compositional matrix adjust.
 Identities = 57/66 (86%), Positives = 64/66 (96%)
 Frame = +3

Query: 145 NLILAMLGEQFMVGEEICGAVVSVRFQEDIISIWNKTASDQATTARIRDTLRRVLNLPPN 204
           NLILAMLGEQFMVGEEICGAVVSVRFQ+DI+++WN+TASDQATT RIRDTL+RVL+LP N
Sbjct: 3   NLILAMLGEQFMVGEEICGAVVSVRFQDDILALWNRTASDQATTTRIRDTLKRVLHLPAN 182

Query: 205 TIMEYK 210
           TIMEYK
Sbjct: 183 TIMEYK 200
>18848
          Length = 925

 Score = 53.5 bits (127), Expect = 7e-08,   Method: Compositional matrix adjust.
 Identities = 24/30 (80%), Positives = 27/30 (90%)
 Frame = -2

Query: 188 TARIRDTLRRVLNLPPNTIMEYKTHTDSIK 217
           T RIRDTL+RVL+LP NTIMEYKTH DS+K
Sbjct: 924 TTRIRDTLKRVLHLPANTIMEYKTHNDSLK 835
>00649
          Length = 2136

 Score = 27.7 bits (60), Expect = 4.5,   Method: Compositional matrix adjust.
 Identities = 20/57 (35%), Positives = 25/57 (43%), Gaps = 3/57 (5%)
 Frame = -3

Query: 72   SYEQNIKQIGTFASVEQFWKFYSHMVRPGDLTGHSDFHLFKEG---IKPMWEDDANK 125
            SYE+  KQI     V   W+        GD T H +  L K+    I  + ED ANK
Sbjct: 1177 SYEEAFKQIKEATGVADTWEVVERFRSQGDTTKHLE-ELKKDNEKQIARLKEDKANK 1010
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|94379323|ref|XP_979015.1| PREDICTED: similar to
Isochorismatase domain-containing protein 2A, mitochondrial [Mus
musculus]
         (206 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

26438                                                                 120   7e-33
02610                                                                  27   5.2  
>26438
          Length = 446

 Score =  120 bits (300), Expect(2) = 7e-33,   Method: Compositional matrix adjust.
 Identities = 65/132 (49%), Positives = 85/132 (64%), Gaps = 3/132 (2%)
 Frame = -2

Query: 65  LGPTVPELGAQGIRPVSKTCFSMV-PALQKELDG--RSQLQSVLLCGIETQACILNTALD 121
           LG    + G  G    ++  FSMV P ++  L      +++ ++L GIET  CI  T +D
Sbjct: 385 LGAGYQQCGVHG----AQDKFSMVLPEVEGTLKTLCEGKVEHIVLFGIETHVCIQQTVID 218

Query: 122 LLHRGLQVHVVVDACSSRSQVDRLVALARMRQSGAFLATSESLILQLVRDASHPQFKEIQ 181
           LL RG +VHVV DACSSRSQ+DRL AL R R  GA + TSE+++LQLV D  HP+FKE+Q
Sbjct: 217 LLARGFEVHVVADACSSRSQMDRLFALERFRHMGATVTTSEAVLLQLVADKDHPKFKEVQ 38

Query: 182 KIIKEPVPDSGL 193
            +IK   PDSGL
Sbjct: 37  ALIKISAPDSGL 2

 Score = 37.4 bits (85), Expect(2) = 7e-33,   Method: Compositional matrix adjust.
 Identities = 15/22 (68%), Positives = 20/22 (90%)
 Frame = -3

Query: 51  LDVPILLTEQYPEGLGPTVPEL 72
           LD+P+++TEQYP+GLG TV EL
Sbjct: 441 LDIPLIVTEQYPKGLGSTVSEL 376
>02610
          Length = 697

 Score = 26.9 bits (58), Expect = 5.2,   Method: Compositional matrix adjust.
 Identities = 15/56 (26%), Positives = 28/56 (50%)
 Frame = -1

Query: 151 MRQSGAFLATSESLILQLVRDASHPQFKEIQKIIKEPVPDSGLLSLFQGQSPLTSC 206
           +R+    L+ S  ++++L   +S  + K+IQK I+EP+   G          L+ C
Sbjct: 451 LRR*FCLLSKSVVIVIELNNASSKEKTKQIQKSIREPLDQRGFCDAVARSKILSFC 284
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|113462019|ref|NP_690022.2| casein kinase 1, gamma 3
[Mus musculus]
         (424 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

18481                                                                 137   8e-33
16959                                                                 108   3e-24
32357                                                                  59   4e-15
01718                                                                  64   1e-10
01707                                                                  55   6e-08
30755                                                                  54   1e-07
09606                                                                  53   3e-07
18921                                                                  50   2e-06
00300                                                                  48   9e-06
21433                                                                  47   1e-05
29581                                                                  47   1e-05
01756                                                                  47   2e-05
26560                                                                  47   2e-05
11780                                                                  46   3e-05
04591                                                                  46   3e-05
14126                                                                  46   4e-05
26711                                                                  45   5e-05
01106                                                                  45   6e-05
11185                                                                  44   1e-04
01060                                                                  43   2e-04
01392                                                                  43   3e-04
26009                                                                  42   4e-04
03240                                                                  42   4e-04
01966                                                                  42   5e-04
27405                                                                  41   7e-04
00715                                                                  41   0.001
13592                                                                  41   0.001
31885                                                                  40   0.002
15910                                                                  40   0.002
21079                                                                  40   0.002
14477                                                                  40   0.002
19094                                                                  39   0.004
21800                                                                  39   0.005
03508                                                                  39   0.005
11404                                                                  38   0.008
04852                                                                  37   0.011
16708                                                                  37   0.013
04138                                                                  37   0.017
19301                                                                  37   0.017
12786                                                                  35   0.043
13066                                                                  35   0.047
07940                                                                  35   0.047
27546                                                                  35   0.067
19761                                                                  35   0.077
28157                                                                  34   0.12 
31489                                                                  33   0.15 
17975                                                                  32   0.51 
14116                                                                  31   0.86 
32359                                                                  26   4.3  
29299                                                                  28   6.9  
>18481
          Length = 437

 Score =  137 bits (345), Expect = 8e-33,   Method: Compositional matrix adjust.
 Identities = 66/144 (45%), Positives = 101/144 (70%)
 Frame = -1

Query: 60  GKNLYTNEYVAIKLEPMKSRAPQLHLEYRFYKQLGSGDGIPQVYYFGPCGKYNAMVLELL 119
           G N    + +A+K+E +  +   LH E + Y+Q+G   G+P +Y++G    +NA+V+ELL
Sbjct: 428 GYNTQDGKDIAVKIEAIDVKHQLLHYEAKVYEQIGRHPGLPTMYHYGTEKHFNALVMELL 249

Query: 120 GPSLEDLFDLCDRTFSLKTVLMIAIQLISRMEYVHSKNLIYRDVKPENFLIGRPGNKAQQ 179
           GPSLE+LF +C R F+LKT+LM++ QL+SR+E++H K  I+RD+KP+NFL+G  G    +
Sbjct: 248 GPSLEELFVICKRRFTLKTILMVSDQLLSRLEFIHQKCFIHRDLKPDNFLMGL-GRHCHR 72

Query: 180 VIHIIDFGLAKEYIDPETKKHIPY 203
            ++IIDFGL+K Y D +   HIPY
Sbjct: 71  -LYIIDFGLSKRYKDTQGTMHIPY 3
>16959
          Length = 1747

 Score =  108 bits (271), Expect = 3e-24,   Method: Compositional matrix adjust.
 Identities = 51/94 (54%), Positives = 67/94 (71%)
 Frame = -1

Query: 233  EALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCENFPEEMATYLRYVR 292
            EALG++ MYF RGSLPWQGLKA T K++ ++I + K ATP++ LC++FP E + +L Y R
Sbjct: 1747 EALGYVLMYFNRGSLPWQGLKAATKKQKCERISEKKIATPVDSLCKSFPSEFSIFLNYSR 1568

Query: 293  RLDFFEKPDYDYLRKLFTDLFDRKGYMFDYEYDW 326
             L F E PDY YLR+LF  LF    + FDY +DW
Sbjct: 1567 DLRFDEGPDYTYLRQLFRVLFRTYNHHFDYAFDW 1466
>32357
          Length = 625

 Score = 59.3 bits (142), Expect(2) = 4e-15,   Method: Compositional matrix adjust.
 Identities = 31/70 (44%), Positives = 45/70 (64%)
 Frame = -2

Query: 37  LMVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPMKSRAPQLHLEYRFYKQLGSG 96
           L+V   +R+ KKIG G+FGE+ LG +  + E VA+KLE   ++ PQL+ E + Y+ L  G
Sbjct: 450 LLVNGKYRLMKKIGSGSFGEIYLGVHNTSGEEVAVKLELKNAKHPQLYYESKLYRVLQGG 271

Query: 97  DGIPQVYYFG 106
            GIP   +FG
Sbjct: 270 VGIPYCRWFG 241

 Score = 39.7 bits (91), Expect(2) = 4e-15,   Method: Compositional matrix adjust.
 Identities = 17/32 (53%), Positives = 28/32 (87%)
 Frame = -3

Query: 137 KTVLMIAIQLISRMEYVHSKNLIYRDVKPENF 168
           +TVLM+A Q+I+R+E +++ N I+RD+KP+NF
Sbjct: 152 ETVLMLADQMINRLE-LYTTNFIHRDLKPDNF 60

 Score = 46.6 bits (109), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 23/44 (52%), Positives = 30/44 (68%)
 Frame = -1

Query: 94  GSGDGIPQVYYFGPCGKYNAMVLELLGPSLEDLFDLCDRTFSLK 137
           GS   I Q+ +  P   YN MV++LLGPSLEDLF+ C R F++K
Sbjct: 274 GSRHSILQMVW--PRKHYNVMVMDLLGPSLEDLFNYCGRKFTMK 149
>01718
          Length = 959

 Score = 63.9 bits (154), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 50/195 (25%), Positives = 89/195 (45%), Gaps = 3/195 (1%)
 Frame = +3

Query: 45  VGKKIGCGNFGELRLGKNLYTNEYVAIKLEPMKSRAPQLHLEYRFYKQLGSGDGIPQVYY 104
           + +KIG G F E+    +  T + +A+K+  M S    +  E +   +L   + +    +
Sbjct: 159 ICEKIGAGFFSEVFKVTHRITGQVMALKMNTMTSNRHNMLREVQLLNRLQHANIL---RF 329

Query: 105 FGPC---GKYNAMVLELLGPSLEDLFDLCDRTFSLKTVLMIAIQLISRMEYVHSKNLIYR 161
            G C   G+ +A+   +   +LE L +  D        + + + L   ++Y+HS   I+R
Sbjct: 330 MGVCVHEGQLHALTEYIPSGNLEQLLEKKDEELPWTQRIQLTLGLARGLDYLHSTRFIHR 509

Query: 162 DVKPENFLIGRPGNKAQQVIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTH 221
           D+  +N LI R  N     + I DFGLA +  DP  K+ +P        G+  +M+    
Sbjct: 510 DLTSKNILIRREDNHGYHAV-IADFGLATKIPDPLDKEKLPT------VGSPYWMAPEVL 668

Query: 222 LGKEQSRRDDLEALG 236
            G   + R DL ++G
Sbjct: 669 NGHFYNERADLFSVG 713
>01707
          Length = 757

 Score = 55.1 bits (131), Expect = 6e-08,   Method: Compositional matrix adjust.
 Identities = 61/225 (27%), Positives = 93/225 (41%), Gaps = 6/225 (2%)
 Frame = +1

Query: 48  KIGCGNFGELRLGKNLYTNEYVAIKLEPMKSRAPQLH----LEYRFYKQLGSGDGIPQVY 103
           KIG G++G +   +N  T++ VAIK        P +      E R  KQL   + +  + 
Sbjct: 85  KIGEGSYGVVFKCRNKETSQLVAIKKFVESEDDPLIKKIAMREIRMLKQLKHPNLVRLIE 264

Query: 104 YFGPCGKYNAMVLELLGPSLEDLFDLCDRTFSLKTVLMIAIQLISRMEYVHSKNLIYRDV 163
            F    + + +V + +  +L +  D   R      V  I  Q +  + + H  N I+RDV
Sbjct: 265 VFRRKKRLH-LVFDYVDHTLLNELDRYPRGLPEPMVKRIIYQTLLAVNFCHQYNTIHRDV 441

Query: 164 KPENFLIGRPGNKAQQVIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLG 223
           KPEN LI R G      + + DFG A+    P         E+     T  Y +    +G
Sbjct: 442 KPENILITRQGQ-----VKLCDFGFARILTGPGD-------EYTDYVATRWYRAPELLVG 585

Query: 224 KEQ-SRRDDLEALGHMFMYFLRGSLPWQGLK-ADTLKERYQKIGD 266
             Q     D+ A+G +F   L G   W G    D L    + +GD
Sbjct: 586 DTQYGPPVDVWAIGCVFAELLTGQALWPGRSDVDQLHLIRKTLGD 720
>30755
          Length = 1137

 Score = 53.5 bits (127), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 38/128 (29%), Positives = 59/128 (46%), Gaps = 1/128 (0%)
 Frame = +2

Query: 131 DRTFSLKTVLMIAIQLISRMEYVHSKNLIYRDVKPENFLIGRPGNKAQQVIHIIDFGLAK 190
           +R F+ +       ++IS + Y+HS+ +IYRD+K EN L+ + G+     I + DFGL K
Sbjct: 14  ERIFTEERTRFYGAEIISALGYLHSQGIIYRDLKLENLLLDKDGH-----IKVADFGLCK 178

Query: 191 EYIDPETKKHIPY-REHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPW 249
           E         I Y R  K+  GT  Y++       +  R  D    G +    + G LP+
Sbjct: 179 E--------DITYGRTTKTFCGTPEYLAPEVLDDNDYGRAVDWWGTGVVMYEMICGRLPF 334

Query: 250 QGLKADTL 257
                D L
Sbjct: 335 YNRDHDVL 358
>09606
          Length = 1300

 Score = 52.8 bits (125), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 55/237 (23%), Positives = 102/237 (43%), Gaps = 18/237 (7%)
 Frame = -3

Query: 42   NFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPMKSRAPQLHLEYRFYKQLGSGDGIPQ 101
            NF + +++G G    +  G+   T  +VAI     K + P++    R    + S   + Q
Sbjct: 1112 NFVLYEELGKGEHSIIYKGRRKGTINFVAIHCIE-KCKRPEVTNTVRMTHDI-SHPNVVQ 939

Query: 102  VYYFGPCGKYNAMVLELL-GPSLEDLFDLCDRTFSLKTVLMIAIQLISRMEYVHSKNLIY 160
             + +     +  +V+EL  G SL D+    D      ++    I L++ + Y+HS  +++
Sbjct: 938  FHEWYETSNHLWLVVELCTGGSLADILAQ-DHHLPETSIRDFGIHLVTGLHYIHSLGILF 762

Query: 161  RDVKPENFLIGRPGNKAQQVIHIIDFGLAKEYIDPETKKHIPYREHKS------------ 208
             D++P   L+   G     V+   DFGL+K  ++ E  + + ++  ++            
Sbjct: 761  HDLRPSKVLLDTSG-----VLKFADFGLSK--VEGENLEELFFKFAEAGDQWNIQSAEEM 603

Query: 209  -----LTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKER 260
                  +G+  YM+     G E S   DL ALG +F     G  P+ G   D  K++
Sbjct: 602  MKQVPTSGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFSGHPPFLGETYDITKDK 432
>18921
          Length = 697

 Score = 50.1 bits (118), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 44/178 (24%), Positives = 83/178 (46%), Gaps = 3/178 (1%)
 Frame = +2

Query: 43  FRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPMKSRAPQLHLEYRFYKQLGSGDGIPQV 102
           F +  K+G G++G +    +  T + +AIK  P+ +   ++  E    +Q    D    V
Sbjct: 35  FDILGKLGEGSYGSVFKSLHKETGQVLAIKQVPVDTDLQEIIKEISIMQQC---DSKYIV 205

Query: 103 YYFGPCGKYNAM--VLELLGP-SLEDLFDLCDRTFSLKTVLMIAIQLISRMEYVHSKNLI 159
            Y+G   K   +  V+E  G  S+ D+  L ++T   + +  I    +  + Y+HS+  I
Sbjct: 206 KYYGSYFKNTDLWIVMEYCGAGSVSDIMRLRNKTLVEREIATILYYTLKGLXYLHSRRKI 385

Query: 160 YRDVKPENFLIGRPGNKAQQVIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMS 217
           +RD+K  N L+   G+       + DFG+A +  D   K++       ++ GT  +M+
Sbjct: 386 HRDIKAGNILLNNEGHA-----KLADFGVAGQLTDTMAKRN-------TVIGTPYWMA 523
>00300
          Length = 2318

 Score = 47.8 bits (112), Expect = 9e-06,   Method: Compositional matrix adjust.
 Identities = 52/229 (22%), Positives = 98/229 (42%), Gaps = 18/229 (7%)
 Frame = -1

Query: 42   NFRV--GKKIGCGNFGELRLGKNLYTNEYVAIKLEPMKSRAPQLHLEYRFYKQLGSGDGI 99
            NFR   G KIG G FG++    N+ T E +A+K   MK +   L        ++   +GI
Sbjct: 1661 NFRWQRGNKIGEGQFGKVYTAVNMSTGELMALK--EMKFQPNDLQQLREMCDEIKIFEGI 1488

Query: 100  PQ---VYYFGPCGKYNAMVLELLGPSLEDLFDLCDRTFSLKTVLMIAI----------QL 146
                 V Y+G     + M++           + CD T +++    + +          ++
Sbjct: 1487 QHENLVKYYGVEVHKDEMLM---------FMEYCD-TGTIEEAAKMGLPEYLIRRYTREI 1338

Query: 147  ISRMEYVHSKNLIYRDVKPENFLIGRPGNKAQQVIHIIDFGLAKEYIDPETKKHIPYREH 206
            +  + ++H  ++++RD+K  N  +   G+     + + DFG +   +  ++   +P   H
Sbjct: 1337 VLAVNHLHENSIVHRDIKGANIFLTSNGH-----VKLGDFGCS---VKLKSHTTMPGEFH 1182

Query: 207  KSLTGTARYMSINTHLGKEQ---SRRDDLEALGHMFMYFLRGSLPWQGL 252
             +L GT  YM+       +Q    R  D+ +LG + +    G  PW  L
Sbjct: 1181 -NLVGTTAYMAPEVFTQNDQGGYGRAADIWSLGCVVIEMATGKRPWHDL 1038
>21433
          Length = 590

 Score = 47.4 bits (111), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 33/104 (31%), Positives = 47/104 (45%)
 Frame = +2

Query: 145 QLISRMEYVHSKNLIYRDVKPENFLIGRPGNKAQQVIHIIDFGLAKEYIDPETKKHIPYR 204
           QL S +EY H + +I+RD+KPEN L        +  + I DFG +          H P  
Sbjct: 191 QLSSALEYCHYRKVIHRDIKPENLL-----LGLKGDLKIADFGWS---------VHAPSS 328

Query: 205 EHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLP 248
              ++ GT  Y+      GK      DL +LG +   FL G+ P
Sbjct: 329 RRTTMCGTLDYLPPEMVEGKTHDENVDLWSLGVLCYEFLVGTPP 460
>29581
          Length = 1278

 Score = 47.4 bits (111), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 28/83 (33%), Positives = 41/83 (49%)
 Frame = -2

Query: 114  MVLELLGPSLEDLFDLCDRTFSLKTVLMIAIQLISRMEYVHSKNLIYRDVKPENFLIGRP 173
            +V+E     L  L D     FS   V  I +QL+  + Y+H   +I+RD+K  N L+   
Sbjct: 1118 LVMEYCEQDLASLLDNMPAPFSESQVKCIVLQLLKGLRYLHEAFIIHRDLKVSNLLMTDK 939

Query: 174  GNKAQQVIHIIDFGLAKEYIDPE 196
            G      + I DFGLA+ Y  P+
Sbjct: 938  G-----CVKIADFGLARNYGKPQ 885
>01756
          Length = 1858

 Score = 47.0 bits (110), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 41/156 (26%), Positives = 69/156 (44%), Gaps = 11/156 (7%)
 Frame = -3

Query: 48   KIGCGNFGELRLGKNLYTNEYVAIK---LEPMKSRAPQLHLEYRFYKQLGSGDGIPQVYY 104
            KIG G FGE+   +   T + VA+K   ++  K   P   L      QL + + +  +  
Sbjct: 1721 KIGQGTFGEVFKARCKKTKQVVAMKKVLMDNEKEGFPITALREIKILQLLNHENVVDLIE 1542

Query: 105  F-----GPCGKYNAM---VLELLGPSLEDLFDLCDRTFSLKTVLMIAIQLISRMEYVHSK 156
                      +Y +M   V E     L  L       F+L  +  +  QL++ + Y+H  
Sbjct: 1541 ICSTKATSANRYKSMFYLVFEFCEHDLAGLLSNMSVVFNLPEIKEVMKQLMNGLYYIHRN 1362

Query: 157  NLIYRDVKPENFLIGRPGNKAQQVIHIIDFGLAKEY 192
             +++RD+K  N LI + G     V+ + DFGLA+ +
Sbjct: 1361 KILHRDMKAANILITKQG-----VLKLADFGLARAF 1269
>26560
          Length = 398

 Score = 46.6 bits (109), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 36/119 (30%), Positives = 61/119 (51%), Gaps = 1/119 (0%)
 Frame = -1

Query: 133 TFSLKTVLMIAIQLISRMEYVHSKNLIYRDVKPENFLIGRPGNKAQQVIHIIDFGLAKEY 192
            F+ K V   A +++  +E++HS+ ++YRD+KP N L+   G+     + I D GLA ++
Sbjct: 368 VFTEKEVRFYAAEVMLGLEHMHSRFVVYRDLKPANILLDENGH-----VRISDLGLACDF 204

Query: 193 IDPETKKHIPYREHKSLTGTARYMSINTHL-GKEQSRRDDLEALGHMFMYFLRGSLPWQ 250
               +KK    R H S+ GT  YM+    + G+      D  + G M    L+G  P++
Sbjct: 203 ----SKK----RPHASV-GTHGYMAPEVLMKGQSYDSSADWFSFGCMLYKLLKGHSPFR 54
>11780
          Length = 1713

 Score = 46.2 bits (108), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 44/156 (28%), Positives = 72/156 (46%), Gaps = 2/156 (1%)
 Frame = +3

Query: 37  LMVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPMKSRAPQLHLEYRFYKQLGSG 96
           ++   +  +G+ IG G+FG++   K +Y  + VAIK    K R  Q  L+          
Sbjct: 585 VIAXQDLEIGEAIGKGDFGDVY--KGMYRGQPVAIKQLKDKDRGEQSFLQEASVMTSLRH 758

Query: 97  DGIPQVYYFGPCGKYNAMVLELLGPS--LEDLFDLCDRTFSLKTVLMIAIQLISRMEYVH 154
           D + ++      G+   +V E +G    +E L        + K  +  A    + MEY+ 
Sbjct: 759 DNLVRLIGV-VLGETIFLVTEFMGKGNLVEYLRSRGRSVITKKDQINFATDTCAAMEYLE 935

Query: 155 SKNLIYRDVKPENFLIGRPGNKAQQVIHIIDFGLAK 190
           SK L++RD+   N L+   G KA+    + DFGLAK
Sbjct: 936 SKRLVHRDLAARNVLVHDDG-KAK----VSDFGLAK 1028
>04591
          Length = 1117

 Score = 45.8 bits (107), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 26/91 (28%), Positives = 48/91 (52%), Gaps = 3/91 (3%)
 Frame = -2

Query: 106 GPCGKYNA---MVLELLGPSLEDLFDLCDRTFSLKTVLMIAIQLISRMEYVHSKNLIYRD 162
           GP  +Y +   ++ E     L  L +     FSL     +  QL++ + Y+H+K +++RD
Sbjct: 999 GPYNRYKSTFYLIFEYCDYDLAGLLNNLRVKFSLADKKNLMSQLLNGLFYIHTKQILHRD 820

Query: 163 VKPENFLIGRPGNKAQQVIHIIDFGLAKEYI 193
           +K  N L+ R G     V+ + DFGL++ ++
Sbjct: 819 IKAANILLTRDG-----VLKLADFGLSRPWV 742
>14126
          Length = 1265

 Score = 45.8 bits (107), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 36/128 (28%), Positives = 63/128 (49%), Gaps = 4/128 (3%)
 Frame = +3

Query: 142 IAIQLISRMEYVHSKNLIYRDVKPENFLIGRPGNKAQQVIHIIDFGLAKEYIDPETKKHI 201
           + +QL++ ++++HS  +++RD+KP+N LI + G      + + DFGLA+           
Sbjct: 531 LMLQLLNGVDFLHSNRIVHRDLKPQNLLISKDGR-----LKLADFGLAR----------- 662

Query: 202 PYREHKSLTG---TARYMSINTHLGKEQSRRDDLEALGHMFM-YFLRGSLPWQGLKADTL 257
            Y  H +LT    T  Y S    +  E     D+ + G +F   F R +L     + D L
Sbjct: 663 IYSFHMALTTVVVTLWYRSPEVLMQAEYGTSVDIWSCGCIFAELFTRRALFKGSSEFDQL 842

Query: 258 KERYQKIG 265
           K+ ++ IG
Sbjct: 843 KKIFEVIG 866
>26711
          Length = 405

 Score = 45.4 bits (106), Expect = 5e-05,   Method: Composition-based stats.
 Identities = 34/119 (28%), Positives = 59/119 (49%)
 Frame = -2

Query: 145 QLISRMEYVHSKNLIYRDVKPENFLIGRPGNKAQQVIHIIDFGLAKEYIDPETKKHIPYR 204
           Q++  +++VH++ +++ D+KP N L+   G+K   V  +IDFGLA++   P+      + 
Sbjct: 392 QVLDILQHVHAQGVVHMDLKPSNLLLS--GDKLDSV-QLIDFGLARKLYPPQET----FL 234

Query: 205 EHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQK 263
            H    GT  + S      K  S   D+  +G +    L G  P+Q   AD+  E  +K
Sbjct: 233 NH----GTPGFTSPEALDVKPISTASDVWGVGVLAYILLSGQSPFQ---ADSATESLKK 78
>01106
          Length = 878

 Score = 45.1 bits (105), Expect = 6e-05,   Method: Compositional matrix adjust.
 Identities = 38/142 (26%), Positives = 66/142 (46%), Gaps = 14/142 (9%)
 Frame = +3

Query: 43  FRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPMKSRAPQLHL-EYRFYKQLGSGDG--- 98
           + V +K+G G+F  + L  +L    +VA+K+        +  L E +  K +   D    
Sbjct: 324 YHVIRKLGWGHFSTVWLCWDLTCKRFVALKVVKSAQHYTETALDEVKLLKCVRESDVADP 503

Query: 99  --------IPQVYYFGPCGKYNAMVLELLGPSLEDLFDLCD-RTFSLKTVLMIAIQLISR 149
                   +      G  G + AMV E+LG +L  L    + +   +  V +I  Q++  
Sbjct: 504 ARAKCVQLLDDFKISGVNGTHVAMVFEVLGYNLLKLIIRSNYQGIPIHNVKLIIRQVLEG 683

Query: 150 MEYVHSK-NLIYRDVKPENFLI 170
           + Y+H+K  +I+ D+KPEN LI
Sbjct: 684 LSYMHAKCRIIHTDIKPENILI 749
>11185
          Length = 473

 Score = 43.9 bits (102), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 30/122 (24%), Positives = 54/122 (44%), Gaps = 17/122 (13%)
 Frame = +1

Query: 142 IAIQLISRMEYVHSKNLIYRDVKPENFLIGRPGNKAQQVIHIIDFGLAKEYIDPETKKHI 201
             I L++ + Y+HS  +++ D++P   L+   G     V+   DFGL+K  ++ E  + +
Sbjct: 16  FGIHLVTGLHYIHSLGILFHDLRPSKVLLDTSG-----VLKFADFGLSK--VEGENLEEL 174

Query: 202 PYREHKS-----------------LTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLR 244
            ++  ++                  +G+  YM+     G E S   DL ALG +F     
Sbjct: 175 FFKFAEAGDQWNIQSAEEMMKQVPTSGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFS 354

Query: 245 GS 246
           GS
Sbjct: 355 GS 360
>01060
          Length = 1800

 Score = 43.1 bits (100), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 36/142 (25%), Positives = 68/142 (47%), Gaps = 2/142 (1%)
 Frame = +1

Query: 143 AIQLISRMEYVHSKNLIYRDVKPENFLIGRPGNKAQQVIHIIDFGLAKEYIDPETKKHIP 202
             Q+++ + + H + +++RD+KP+N LI   G      I I DFG+A+ +        +P
Sbjct: 394 VFQIVTGIXFCHQRRIVHRDLKPQNLLINHTG-----AIKIADFGMARTF-------ALP 537

Query: 203 YREHKSLTGTARYMSINTHLGKEQ-SRRDDLEALGHMFMYFLRGSLPWQG-LKADTLKER 260
            R +     T  Y +    +G  + S   D+ ++G +F   L  +  ++G  + D L + 
Sbjct: 538 VRAYTHEVVTLWYRAPEILMGASKYSTPVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKI 717

Query: 261 YQKIGDTKRATPIEVLCENFPE 282
           ++ IG     TP E   + +PE
Sbjct: 718 FRIIG-----TPTE---QTWPE 759
>01392
          Length = 1806

 Score = 42.7 bits (99), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 39/129 (30%), Positives = 62/129 (48%), Gaps = 6/129 (4%)
 Frame = -1

Query: 129  LCDRTFSLKTVLMIAIQLISR-MEYVHSKNLIYRDVKPENFLIGRPGNKAQQVIHIIDFG 187
            LC+R  SL       ++ I+R ++++HSK + +RD+KPEN L     +     + I DF 
Sbjct: 1800 LCEREASL------VVRHIARALDFLHSKGIAHRDLKPENILCEHLDDVVP--VKICDFD 1645

Query: 188  LAKEYIDPETKKHIPYREHKSLTGTARYMS---INTHLGKEQS--RRDDLEALGHMFMYF 242
            LA            P  E  +  G+A YM+   ++  +G   S  +R DL +LG +    
Sbjct: 1644 LASGISCDGDGTKTP--ELLTPVGSAEYMAPEVVDAWVGDSFSYDKRCDLWSLGIILYIM 1471

Query: 243  LRGSLPWQG 251
            L G  P+ G
Sbjct: 1470 LCGYPPFYG 1444
>26009
          Length = 886

 Score = 42.4 bits (98), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 16/29 (55%), Positives = 24/29 (82%)
 Frame = +3

Query: 145 QLISRMEYVHSKNLIYRDVKPENFLIGRP 173
           QL+S ++++HSK L++RD+KPEN LI  P
Sbjct: 735 QLVSALDFMHSKQLVHRDIKPENVLILTP 821
>03240
          Length = 1683

 Score = 42.4 bits (98), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 43/153 (28%), Positives = 65/153 (42%), Gaps = 6/153 (3%)
 Frame = -3

Query: 43   FRVGKKIGCGNFGELRLGKNLYTNEYVAIKL---EPMKSRAPQLHLEY-RFYKQLGSGDG 98
            F   K +G G FGE+ L +   T    A+K      +  R    H++  R        + 
Sbjct: 1285 FEKIKTLGVGAFGEVSLCRKNDTGMLYAMKTLRKSDVLKRNQVAHVKAERDILAEADNEW 1106

Query: 99   IPQVYYFGPCGKYNAMVLELLGPSLEDLFDLCDRTFSLKTVL--MIAIQLISRMEYVHSK 156
            + ++YY      Y   V++ +     DL  L  R   L   L      +L+  +E VH  
Sbjct: 1105 VVKLYYSFQDHNYLYFVMDYVPGG--DLMGLLIRMEILDEPLARFYVAELVQAIESVHRM 932

Query: 157  NLIYRDVKPENFLIGRPGNKAQQVIHIIDFGLA 189
              I+RD+KP+N LI R G+     I + DFGL 
Sbjct: 931  GFIHRDIKPDNILIDRNGH-----IKLTDFGLC 848
>01966
          Length = 1735

 Score = 42.0 bits (97), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 17/51 (33%), Positives = 31/51 (60%)
 Frame = -1

Query: 145  QLISRMEYVHSKNLIYRDVKPENFLIGRPGNKAQQVIHIIDFGLAKEYIDP 195
            Q+++ + + H + +++RD+KP+N LI   G      I I DFG+A+ +  P
Sbjct: 1384 QIVTGINFCHQRRIVHRDLKPQNLLINHTG-----AIKIADFGMARTFALP 1247
>27405
          Length = 532

 Score = 41.2 bits (95), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 28/85 (32%), Positives = 48/85 (56%)
 Frame = -3

Query: 133 TFSLKTVLMIAIQLISRMEYVHSKNLIYRDVKPENFLIGRPGNKAQQVIHIIDFGLAKEY 192
            F+ K V   A +++  +E++HS+ ++YRD+KP N L+   G+     + I D GLA ++
Sbjct: 266 VFTEKEVRFYAAEVMLGLEHMHSRFVVYRDLKPANILLDENGH-----VRISDLGLACDF 102

Query: 193 IDPETKKHIPYREHKSLTGTARYMS 217
               +KK    + H S+ GT  YM+
Sbjct: 101 ----SKK----KPHASV-GTHGYMA 54
>00715
          Length = 1788

 Score = 40.8 bits (94), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 41/177 (23%), Positives = 71/177 (40%), Gaps = 18/177 (10%)
 Frame = +1

Query: 114 MVLELLGP-SLEDLFDLCDRTFSLKTVLMIAIQLISRMEYVHSKNLIYRDVKPENFLIGR 172
           + +E +GP +L+ + +   +       L +A+Q+   + Y+HS N+++ D+KP N L+ R
Sbjct: 166 LAMEYVGPLNLQTILNDHQQDIDSSMRLSLALQMARGLHYLHSINIVHLDLKPANCLLTR 345

Query: 173 PGNKAQQVIHIIDFGLAKEYIDPETKKHIPYRE-----------------HKSLTGTARY 215
                   + I DFG   +     T   +  RE                    L GT  Y
Sbjct: 346 -----DLKLRIADFGCCHQLT--PTGLDMGEREGGMAGNELELTPVQGAWKNELAGTLAY 504

Query: 216 MSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATP 272
            +     G + S R D+ +LG           P++G+ A  +   YQ +    R  P
Sbjct: 505 RAPELLKGLQPSVRSDVYSLGITLWQMCTRQGPYEGVPAHAVV--YQVVSKDLRPCP 669
>13592
          Length = 980

 Score = 40.8 bits (94), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 52/213 (24%), Positives = 92/213 (43%), Gaps = 11/213 (5%)
 Frame = +2

Query: 48  KIGCGNFGELRLGKNLYTNEYVAIK---LEPMKSRAPQLHLEYRFYKQLGSGDGIPQ--- 101
           KIG G FG++    N  T E +A+K   ++P ++RA +        ++L   +GI     
Sbjct: 5   KIGQGRFGKVYTAVNNNTGELMAMKEIAIQPGETRALK-----NVAEELKILEGIKHKNL 169

Query: 102 VYYFGPCGKYNAMVLELLGPSLEDLFDLCDRTFSLKTVLM--IAIQLISRMEYVHSKNLI 159
           V Y+G       +++ +   S   L  L + T  L   L      QL+S +  +H   ++
Sbjct: 170 VRYYGIEVHREELLIFMELCSEGTLESLVELTGGLPEALSRRFTAQLLSGVAELHKHGIV 349

Query: 160 YRDVKPENFLIGRPGNKAQQVIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMS-- 217
           +RD+K  N  +    N     + + DFG A   +  +    +P  E +   GT  YM+  
Sbjct: 350 HRDIKTANIFLVDGSNS----LKLGDFGSA---VKIQAHTTVP-GELQGYVGTQAYMAPE 505

Query: 218 INTHLGKE-QSRRDDLEALGHMFMYFLRGSLPW 249
           + T    +   R  D+ ++G + +    G  PW
Sbjct: 506 VFTKTNSDGHGRLADIWSVGCVVVEMASGKRPW 604
>31885
          Length = 529

 Score = 40.0 bits (92), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 31/125 (24%), Positives = 54/125 (43%), Gaps = 5/125 (4%)
 Frame = -2

Query: 145 QLISRMEYVHSKNLIYRDVKPENFLIGRPGNKAQQVIHIIDFGLAKEYIDPETKKHIPYR 204
           QL   ++Y+ S+ +++RD+KP+N L+   G+      H+ DF +A +  D E        
Sbjct: 348 QLALVLDYLRSQKIVHRDIKPDNILLDEQGH-----CHVTDFNIATQLEDDELA------ 202

Query: 205 EHKSLTGTARYMSINTHLGKEQSRRD-----DLEALGHMFMYFLRGSLPWQGLKADTLKE 259
              S +GT  YM+   +      RR      D  +LG      L+   P+      +L E
Sbjct: 201 --TSTSGTRPYMAPEVYGVAINERRGYGFPVDWWSLGVSLFELLKKRRPFSVHSNTSLHE 28

Query: 260 RYQKI 264
            +  +
Sbjct: 27  MWATM 13
>15910
          Length = 1361

 Score = 40.0 bits (92), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 30/119 (25%), Positives = 61/119 (51%)
 Frame = +2

Query: 146 LISRMEYVHSKNLIYRDVKPENFLIGRPGNKAQQVIHIIDFGLAKEYIDPETKKHIPYRE 205
           ++  ++Y+H+  +++RD+KPEN L     + ++  + + DFGL++  I+PE        +
Sbjct: 491 ILHGVQYIHANGVVHRDLKPENLLYECMTDDSK--LKLADFGLSR-IIEPEV-------Q 640

Query: 206 HKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKI 264
             ++ GT  Y +     G + +   D+ ++G +    L G  P+    A+   E Y+KI
Sbjct: 641 MSTVCGTPGYCAPEVLKGDKYTPSVDMWSVGVIAYILLCGYEPFF---AENEFEMYRKI 808
>21079
          Length = 878

 Score = 39.7 bits (91), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 30/104 (28%), Positives = 52/104 (50%)
 Frame = +1

Query: 145 QLISRMEYVHSKNLIYRDVKPENFLIGRPGNKAQQVIHIIDFGLAKEYIDPETKKHIPYR 204
           Q+ S + Y+H++++++ D+KPEN L     + + Q I IIDFGLA+ Y         P  
Sbjct: 151 QICSGVGYMHTQSILHLDLKPENVLC--VSDNSNQ-IKIIDFGLARFY--------KPGD 297

Query: 205 EHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLP 248
             + L GT  +++       E +   D+ ++G +    L G  P
Sbjct: 298 SLQVLFGTPEFIAPEVVNYDEINFTTDMWSIGVICYILLSGLSP 429
>14477
          Length = 493

 Score = 39.7 bits (91), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 37/149 (24%), Positives = 68/149 (45%), Gaps = 6/149 (4%)
 Frame = -1

Query: 48  KIGCGNFGELRLGKNLYTNEYVAIKLEPMKSRAPQLHLEYRFYKQ---LGSGDGIPQVYY 104
           K+G GNFG +  G     +  + + ++ +K+      ++    K+   +   D +  V  
Sbjct: 469 KLGAGNFGSVMKGVCRLDDREIPVAIKVLKNADLDPSVQSELIKEAEVMKKMDHMHIVRL 290

Query: 105 FGPC-GKYNAMVLEL--LGPSLEDLFDLCDRTFSLKTVLMIAIQLISRMEYVHSKNLIYR 161
            G C G+   +VLEL  LGP   + F   ++   L  +L +  Q+   MEY+ +   ++R
Sbjct: 289 IGLCEGETMMLVLELAKLGPL--NKFLPKNKHLPLWNILELMWQVSQGMEYLEANKFVHR 116

Query: 162 DVKPENFLIGRPGNKAQQVIHIIDFGLAK 190
           D+   N L+       +    I DFG++K
Sbjct: 115 DLAARNILLCD-----EHFAKISDFGMSK 44
>19094
          Length = 898

 Score = 38.9 bits (89), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 24/96 (25%), Positives = 47/96 (48%)
 Frame = +1

Query: 122 SLEDLFDLCDRTFSLKTVLMIAIQLISRMEYVHSKNLIYRDVKPENFLIGRPGNKAQQVI 181
           S+ D+  L ++T   + +  I    +  + Y+HS+  I+RD+K  N L+   G+      
Sbjct: 13  SVSDIMRLRNKTLVEREIATILYYTLKGL*YLHSRRKIHRDIKAGNILLNNEGHA----- 177

Query: 182 HIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMS 217
            + DFG+A +  D   K++       ++ GT  +M+
Sbjct: 178 KLADFGVAGQLTDTMAKRN-------TVIGTPYWMA 264
>21800
          Length = 855

 Score = 38.5 bits (88), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 25/72 (34%), Positives = 40/72 (55%), Gaps = 2/72 (2%)
 Frame = +2

Query: 106 GPCGKYNAMVLELLGPSLEDLFDLCD-RTFSLKTVLMIAIQLISRMEYVHSK-NLIYRDV 163
           G  G +  MV E+LG +L  L    + +   +  V +I  Q++  + Y+H+K N+I+ D+
Sbjct: 536 GVNGTHVCMVFEVLGYNLLKLIIRSNYQGIPVHNVKLIIRQVLEGLNYLHAKCNIIHTDI 715

Query: 164 KPENFLIGRPGN 175
           KPEN LI    N
Sbjct: 716 KPENILICVDDN 751
>03508
          Length = 1463

 Score = 38.5 bits (88), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 19/61 (31%), Positives = 35/61 (57%)
 Frame = +1

Query: 132 RTFSLKTVLMIAIQLISRMEYVHSKNLIYRDVKPENFLIGRPGNKAQQVIHIIDFGLAKE 191
           +TF+   +     +L+  +++ HS  +++RDVKP N +I     K    + +ID+GLA+ 
Sbjct: 856 QTFTDYDIRFYLYELMKALDFCHSMGIMHRDVKPHNVMIDHENKK----LRLIDWGLAEF 1023

Query: 192 Y 192
           Y
Sbjct: 1024Y 1026
>11404
          Length = 563

 Score = 37.7 bits (86), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 38/140 (27%), Positives = 67/140 (47%), Gaps = 12/140 (8%)
 Frame = +1

Query: 43  FRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPMKSRAP---QLHLEYRFYKQLGSGDGI 99
           + +   IG G+FG++    +   NE VAIK+  +K++ P   Q  +E +  + +   D  
Sbjct: 145 YEIDSLIGKGSFGQVVKAYDHTDNEQVAIKI--IKNKKPFLNQAQIEVKLLEMMNRHD-T 315

Query: 100 PQVYYFGPCGKYN------AMVLELLGPSLEDLFDLCD-RTFSLKTVLMIAIQLISRMEY 152
              YY     ++        +V ELL  +L DL    + R  SL      A QL + + +
Sbjct: 316 DNKYYIVRLKRHFMFRSHLCLVFELLSYNLYDLLRNTNFRGVSLNLTRKFAQQLCTALLF 495

Query: 153 VHS--KNLIYRDVKPENFLI 170
           + +   ++I+ D+KPEN L+
Sbjct: 496 LATPEMSIIHCDLKPENILL 555
>04852
          Length = 1462

 Score = 37.4 bits (85), Expect = 0.011,   Method: Compositional matrix adjust.
 Identities = 31/139 (22%), Positives = 60/139 (43%), Gaps = 3/139 (2%)
 Frame = +1

Query: 137 KTVLMIAIQLISRMEYVHSKNLIYRDVKPENFLIGRPGNKAQQVIHIIDFGLAK--EYID 194
           K +L  A Q+   ME++ S+  I+RD+   N L+       + V+ I DFGL++  +Y  
Sbjct: 325 KNLLSYAFQIARGMEFLASRKCIHRDLAARNVLV-----TEEHVLKIADFGLSRTGDYYK 489

Query: 195 PETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALG-HMFMYFLRGSLPWQGLK 253
             +   +P           ++M+         + + D+ + G  ++  F  G +P+  + 
Sbjct: 490 KRSGGRLP----------VKWMAPEALFDMRYTTKSDVWSFGVVLWEIFSLGGMPYASIP 639

Query: 254 ADTLKERYQKIGDTKRATP 272
            + L   Y K+ D     P
Sbjct: 640 NEEL---YSKLLDDAYRMP 687
>16708
          Length = 1397

 Score = 37.4 bits (85), Expect = 0.013,   Method: Compositional matrix adjust.
 Identities = 30/112 (26%), Positives = 45/112 (40%), Gaps = 1/112 (0%)
 Frame = -1

Query: 139  VLMIAIQLISRMEYVHSKNLIYRDVKPENFLIGRPGNKAQQVIHIIDFGLAKEY-IDPET 197
            V  IA Q +  +E++H   +++ DVK +N L+   GN       + D+G+A+ Y + P  
Sbjct: 1088 VCCIAGQXVCALEHIHELGVVHMDVKADNVLVDAHGN-----CKLTDYGIAQLYKVYPA- 927

Query: 198  KKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPW 249
                P   H S     R            S R   E  G    YF  G + W
Sbjct: 926  ----PTETHSSGCTNKRTFYTRPPATMTPSERFSEEGDGIGTDYFRLGQMLW 783
>04138
          Length = 800

 Score = 37.0 bits (84), Expect = 0.017,   Method: Compositional matrix adjust.
 Identities = 16/44 (36%), Positives = 27/44 (61%)
 Frame = +1

Query: 149 RMEYVHSKNLIYRDVKPENFLIGRPGNKAQQVIHIIDFGLAKEY 192
           R+ Y+H   +++RD+K  N LI + G     V+ + DFGLA+ +
Sbjct: 49  RLYYIHRNKILHRDMKAANILITKQG-----VLKLADFGLARAF 165
>19301
          Length = 712

 Score = 37.0 bits (84), Expect = 0.017,   Method: Compositional matrix adjust.
 Identities = 19/51 (37%), Positives = 29/51 (56%)
 Frame = +2

Query: 139 VLMIAIQLISRMEYVHSKNLIYRDVKPENFLIGRPGNKAQQVIHIIDFGLA 189
           VL  + Q+ S M Y+HS  +I+RD+K  N L+ +       V+ I DFG +
Sbjct: 575 VLDWSKQIASGMNYLHSHKIIHRDLKSPNVLVAK-----NDVVKISDFGTS 712
>12786
          Length = 460

 Score = 35.4 bits (80), Expect = 0.043,   Method: Compositional matrix adjust.
 Identities = 26/94 (27%), Positives = 46/94 (48%), Gaps = 1/94 (1%)
 Frame = -3

Query: 145 QLISRMEYVHSKNLIYRDVKPENFLIGRPGNKAQQVIHIIDFGLAKEYIDPETKKHIPYR 204
           +++  ++ +H++ +I+ D+KP NF++   GN     + +IDFG+A      +T      R
Sbjct: 386 EMLRAVKALHNEGVIHSDLKPANFML-VAGN-----LKLIDFGIANTLQQDKTSVLKDSR 225

Query: 205 EHKSLTGTARYMSINTHLGK-EQSRRDDLEALGH 237
                 GT  YMS    +   + S  D +E  GH
Sbjct: 224 -----VGTPSYMSPEAIMAACDDSADDSMEEDGH 138
>13066
          Length = 551

 Score = 35.4 bits (80), Expect = 0.047,   Method: Compositional matrix adjust.
 Identities = 20/73 (27%), Positives = 38/73 (52%)
 Frame = +3

Query: 145 QLISRMEYVHSKNLIYRDVKPENFLIGRPGNKAQQVIHIIDFGLAKEYIDPETKKHIPYR 204
           Q+ + + Y+HS ++ +RD+K EN L+    N     + + DFG A   I    +K++   
Sbjct: 300 QMTTALNYLHSYDVAHRDLKCENILLSSHFN-----VKLADFGFACACITESGEKYMS-- 458

Query: 205 EHKSLTGTARYMS 217
             ++  G+A Y +
Sbjct: 459 --RTYCGSAAYAA 491
>07940
          Length = 1336

 Score = 35.4 bits (80), Expect = 0.047,   Method: Compositional matrix adjust.
 Identities = 19/54 (35%), Positives = 29/54 (53%)
 Frame = -3

Query: 137 KTVLMIAIQLISRMEYVHSKNLIYRDVKPENFLIGRPGNKAQQVIHIIDFGLAK 190
           K ++  A Q+   MEY+ SK  I+RD+   N L+       + V+ I DFGL +
Sbjct: 347 KDLISYAYQVARGMEYLASKQCIHRDLAARNVLVAE-----EYVLKIADFGLTR 201
>27546
          Length = 426

 Score = 34.7 bits (78), Expect = 0.067,   Method: Compositional matrix adjust.
 Identities = 16/46 (34%), Positives = 28/46 (60%)
 Frame = -1

Query: 145 QLISRMEYVHSKNLIYRDVKPENFLIGRPGNKAQQVIHIIDFGLAK 190
           Q+   ++Y+HS ++ +RD+K EN L+ +  N     + I DFG A+
Sbjct: 156 QMAKALQYLHSHDIAHRDLKCENILLSKRLN-----VKIADFGFAR 34
>19761
          Length = 473

 Score = 34.7 bits (78), Expect = 0.077,   Method: Compositional matrix adjust.
 Identities = 24/98 (24%), Positives = 46/98 (46%), Gaps = 2/98 (2%)
 Frame = -3

Query: 144 IQLISRMEYVHSKN--LIYRDVKPENFLIGRPGNKAQQVIHIIDFGLAKEYIDPETKKHI 201
           +Q  S + Y+H+    +++RD+KP+N  +   G+     + + D GLA++   P      
Sbjct: 402 MQTASALNYMHTHTPVILHRDLKPQNIYVTEKGD-----VRLGDLGLARKLTGPADFA-- 244

Query: 202 PYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMF 239
                 S  GT  Y+S      +  + + D+ +LG +F
Sbjct: 243 -----TSQVGTIMYLSPEILSQQPYNSKSDIWSLGCVF 145
>28157
          Length = 400

 Score = 33.9 bits (76), Expect = 0.12,   Method: Compositional matrix adjust.
 Identities = 20/49 (40%), Positives = 28/49 (57%), Gaps = 3/49 (6%)
 Frame = +3

Query: 144 IQLISRMEYVHS---KNLIYRDVKPENFLIGRPGNKAQQVIHIIDFGLA 189
           +Q    +EY+H    K LI+RD+KP N L+ + G K    + I DFG A
Sbjct: 237 LQCALGVEYLHGMKPKALIHRDLKPPNLLLIQCGTK----LKICDFGTA 371
>31489
          Length = 329

 Score = 33.5 bits (75), Expect = 0.15,   Method: Composition-based stats.
 Identities = 12/39 (30%), Positives = 25/39 (64%)
 Frame = +3

Query: 131 DRTFSLKTVLMIAIQLISRMEYVHSKNLIYRDVKPENFL 169
           D+  + + +     Q++  ++Y+HS N+++RD+KP N L
Sbjct: 147 DQPLTEEHIRYFLYQILRGLKYIHSANVVHRDLKPSNLL 263
>17975
          Length = 449

 Score = 32.0 bits (71), Expect = 0.51,   Method: Compositional matrix adjust.
 Identities = 14/46 (30%), Positives = 28/46 (60%), Gaps = 1/46 (2%)
 Frame = +3

Query: 145 QLISRMEYVHSKNLIYRDVKPENFL-IGRPGNKAQQVIHIIDFGLA 189
           Q++  + Y H  ++++RD+KPEN +   +PG     ++ + DFG +
Sbjct: 291 QIVEAISYCHKLHVVHRDLKPENVVFFEKPG-----LVKLTDFGFS 413
>14116
          Length = 1017

 Score = 31.2 bits (69), Expect = 0.86,   Method: Compositional matrix adjust.
 Identities = 18/70 (25%), Positives = 34/70 (48%), Gaps = 5/70 (7%)
 Frame = -1

Query: 135 SLKTVLMIAIQLISRMEYVHSKNLIYRDVKPENFLIGRPGNKAQQVIHIIDFGLA----- 189
           ++K ++M  + +   M+Y+     ++RD+   N ++    +     + + DFGLA     
Sbjct: 327 TIKDLIMYGVDIARGMDYLAGLKFVHRDLAARNCMLDEDFH-----VKVADFGLARDIYE 163

Query: 190 KEYIDPETKK 199
           KEY   E KK
Sbjct: 162 KEYYSSENKK 133
>32359
          Length = 928

 Score = 26.2 bits (56), Expect(2) = 4.3,   Method: Compositional matrix adjust.
 Identities = 27/122 (22%), Positives = 54/122 (44%), Gaps = 8/122 (6%)
 Frame = -1

Query: 46  GKKIGCGNFGELRLGKNLYTNEYVAIKLEPMKSRAPQLHLEYRFYKQLGSGDGIPQVYYF 105
            K IG G+FG +   K + T+E VAIK      R     L+    ++L   + +   ++F
Sbjct: 415 AKVIGNGSFGVVYQAKLVDTSELVAIKKVLQDKRFKNRELQ--IMRKLEHQNIVKLKFFF 242

Query: 106 GPCGK-----YNAMVLELLGPSLEDL---FDLCDRTFSLKTVLMIAIQLISRMEYVHSKN 157
              G+     +  +VLE +  ++  +   +    +T  +  + +   QL   + Y+HS+ 
Sbjct: 241 YSSGEKKDEVFLNLVLEYVPETVYRVARHYSKSKQTIPILYIKLYMYQLFRSLAYIHSQA 62

Query: 158 LI 159
            +
Sbjct: 61  CV 56

 Score = 20.8 bits (42), Expect(2) = 4.3,   Method: Compositional matrix adjust.
 Identities = 6/11 (54%), Positives = 10/11 (90%)
 Frame = -3

Query: 160 YRDVKPENFLI 170
           +RD+KP+N L+
Sbjct: 56  HRDIKPQNLLL 24
>29299
          Length = 366

 Score = 28.1 bits (61), Expect = 6.9,   Method: Composition-based stats.
 Identities = 15/55 (27%), Positives = 30/55 (54%), Gaps = 2/55 (3%)
 Frame = -2

Query: 345 SSNREAHQHRDKIQQSKNQVVSSTNGELNTDD--PTAGRSNAPITAPTEVEVMDE 397
           S N ++H++ +  Q++ + ++   NG+LNT D   T  + N  +  P+   V+ E
Sbjct: 314 SDNPDSHKYVN--QETMHIIIDKINGDLNTSDLSQTVMQVNCSVVPPSNSSVLVE 156
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|164698474|ref|NP_035500.2| cytoplasmic FMR1
interacting protein 1 [Mus musculus]
         (1253 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

12370                                                                 139   8e-33
>12370
          Length = 731

 Score =  139 bits (350), Expect = 8e-33,   Method: Composition-based stats.
 Identities = 61/92 (66%), Positives = 77/92 (83%)
 Frame = -1

Query: 1162 CMIIVLLGQQRRFAVLDFCYHLLKVQKHDGKDEIIKNVPLKKMVERIRKFQILNDEIITI 1221
            C++IVLLGQQRRF  LDFCYH+L+VQ+ DGKDE +K + LK+MV+RIR+FQ+LN +I +I
Sbjct: 731  CVMIVLLGQQRRFEALDFCYHILRVQRVDGKDEDVKGIQLKRMVDRIRRFQVLNSQIFSI 552

Query: 1222 LDKYLKSGDGESTPVEHVRCFQPPIHQSLASS 1253
            L+KYLK GDGE + VEHVRCF PP H S+ SS
Sbjct: 551  LNKYLKGGDGEGSNVEHVRCFPPPQHPSVISS 456
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|51036613|ref|NP_032057.2| fragile X mental
retardation protein 1 [Mus musculus]
         (614 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

19295                                                                 138   8e-33
09541                                                                  32   0.62 
20748                                                                  32   0.70 
26269                                                                  29   5.4  
27455                                                                  29   6.9  
>19295
          Length = 419

 Score =  138 bits (347), Expect = 8e-33,   Method: Composition-based stats.
 Identities = 71/140 (50%), Positives = 100/140 (71%), Gaps = 1/140 (0%)
 Frame = +3

Query: 144 ESAHKDFKKAVGAFS-VTYDPENYQLVILSINEVTSKRAHMLIDMHFRSLRTKLSLILRN 202
           E A  + KK +G  + V+Y+  +  + +L+ +   +KRA M+ DM  R++R KL L +R 
Sbjct: 3   EGALSELKKHLGGGAMVSYNTADNSIHVLATSTAVTKRASMIGDMFLRNVRQKLLLKMRT 182

Query: 203 EEASKQLESSRQLASRFHEQFIVREDLMGLAIGTHGANIQQARKVPGVTAIDLDEDTCTF 262
           EEA K+L+S++ + S + E+F VREDLMGLAIGTHGANIQQARK+  +T I+LDE TCTF
Sbjct: 183 EEAVKKLQSTK-IRSGYMEEFAVREDLMGLAIGTHGANIQQARKIEHITGIELDESTCTF 359

Query: 263 HIYGEDQDAVKKARSFLEFA 282
            +YGE  +AVK+AR  LEF+
Sbjct: 360 KVYGETTEAVKQARGMLEFS 419
>09541
          Length = 2010

 Score = 32.3 bits (72), Expect = 0.62,   Method: Compositional matrix adjust.
 Identities = 17/40 (42%), Positives = 29/40 (72%)
 Frame = -1

Query: 286 IQVPRNLVGKVIGKNGKLIQEIVDKSGVVRVRIEAENEKS 325
           I VPR  VG VIGK G++I++I ++SG  +V+ + ++ +S
Sbjct: 234 IPVPRQAVGLVIGKGGEMIKKIQNESG-AKVQFKPDDGQS 118
>20748
          Length = 847

 Score = 32.0 bits (71), Expect = 0.70,   Method: Compositional matrix adjust.
 Identities = 13/26 (50%), Positives = 18/26 (69%)
 Frame = -2

Query: 286 IQVPRNLVGKVIGKNGKLIQEIVDKS 311
           I  P NL G++IGK G +I+  +DKS
Sbjct: 654 ILCPNNLCGRIIGKKGIVIKGFMDKS 577
>26269
          Length = 679

 Score = 29.3 bits (64), Expect = 5.4,   Method: Compositional matrix adjust.
 Identities = 13/22 (59%), Positives = 17/22 (77%)
 Frame = -3

Query: 286 IQVPRNLVGKVIGKNGKLIQEI 307
           I VPR  VG VIGK G++I++I
Sbjct: 380 IPVPRQAVGLVIGKGGEMIKKI 315
>27455
          Length = 530

 Score = 28.9 bits (63), Expect = 6.9,   Method: Composition-based stats.
 Identities = 11/25 (44%), Positives = 16/25 (64%)
 Frame = -2

Query: 160 TYDPENYQLVILSINEVTSKRAHML 184
           T+DP NY++V+LS   +   R H L
Sbjct: 529 TFDPMNYRMVLLSAQNIPHLRFHQL 455
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|8567358|ref|NP_059497.1| guanylate cyclase 1,
soluble, beta 3 [Mus musculus]
         (620 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

34057                                                                  88   8e-33
29215                                                                  72   7e-13
17954                                                                  72   8e-13
25960                                                                  60   2e-09
09572                                                                  42   5e-04
13236                                                                  29   4.7  
>34057
          Length = 724

 Score = 87.8 bits (216), Expect(2) = 8e-33,   Method: Compositional matrix adjust.
 Identities = 53/133 (39%), Positives = 78/133 (58%), Gaps = 4/133 (3%)
 Frame = +3

Query: 384 EDEKKKTDTLLYSVLPPSVANELRHKRPVPAKRYDNVTILFSGIVGFNAFCSKHASGEGA 443
           + EKK+TDTLLY +LP SVA++L+    V A+ Y   TI FS I GF    ++ +     
Sbjct: 117 KQEKKRTDTLLYQMLPKSVADQLKRNEVVTAETYSESTIFFSDIQGFTQISARSS----P 284

Query: 444 MKIVNLLNDLYTRFD---TLTDSRKNPFVYKVETVGDKYMTVSGLPEP-CIHHARSICHL 499
           +++V +LN LY  FD    L D      VYKVET+GD YM VSG+P+     HA  I  +
Sbjct: 285 VQVVEMLNSLYLCFDERLALYD------VYKVETIGDAYMVVSGVPKKNGKRHAAEIGTM 446

Query: 500 ALDMMEIAGQVQV 512
            LD+++   ++++
Sbjct: 447 TLDLLDSISRLEI 485

 Score = 71.6 bits (174), Expect(2) = 8e-33,   Method: Compositional matrix adjust.
 Identities = 29/70 (41%), Positives = 48/70 (68%)
 Frame = +2

Query: 505 EIAGQVQVDGESVQITIGIHTGEVVTGVIGQRMPRYCLFGNTVNLTSRTETTGEKGKINV 564
           +  G   + G   ++ IG H+G VV GV+G +MPRYCLFG TV++ ++ E+ G+ G+I++
Sbjct: 470 QPPGDPHLPGTKFKLRIGCHSGPVVAGVVGSKMPRYCLFGETVSVAAKMESLGKPGRIHI 649

Query: 565 SEYTYRCLMS 574
           S+ T+  L+S
Sbjct: 650 SQTTHDALLS 679
>29215
          Length = 698

 Score = 72.0 bits (175), Expect = 7e-13,   Method: Compositional matrix adjust.
 Identities = 39/76 (51%), Positives = 49/76 (64%)
 Frame = -1

Query: 532 VIGQRMPRYCLFGNTVNLTSRTETTGEKGKINVSEYTYRCLMSPENSDPLFHLEHRGPVS 591
           V+G +MPRYCLFG+TVN  SR E+TGE  KI VS  TY  L+S  +    + LE RG V 
Sbjct: 698 VVGSKMPRYCLFGDTVNTASRMESTGEADKIQVSRGTYHALLSMTSE---YTLEPRGAVE 528

Query: 592 MKGKKEPMQVWFLSRK 607
           +KGK  PM  ++L  K
Sbjct: 527 IKGKG-PMDTYWLMDK 483
>17954
          Length = 481

 Score = 71.6 bits (174), Expect = 8e-13,   Method: Composition-based stats.
 Identities = 45/125 (36%), Positives = 62/125 (49%), Gaps = 3/125 (2%)
 Frame = -1

Query: 21  VWEDIKKEAQLDEEGQFLVRIIYDDSKTYDLVAAASKVLN---LNAGEILQMFGKMFFVF 77
           VWE I +EA L    Q+    +Y D     L AA S+VL          +Q FG+ F  F
Sbjct: 373 VWERILEEAGLSGV-QYCTHSLYPDGHMRRLAAAHSRVLCDQFPTMDRSMQYFGQCFVKF 197

Query: 78  CQESGYDTILRVLGSNVREFLQNLDALHDHLATIYPGMRAPSFRCTDAEKGKGLILHYYS 137
           C+  G+  IL+V G + R+FL  +D LH+ +  +YP M +P F     E   G +L Y S
Sbjct: 196 CKRCGHANILKVAGRHYRDFLHGIDNLHEMMRFVYPHMHSPYF-LVQHEDQHGCVLVYRS 20

Query: 138 EREGL 142
            R G 
Sbjct: 19  ARTGF 5
>25960
          Length = 420

 Score = 60.1 bits (144), Expect = 2e-09,   Method: Composition-based stats.
 Identities = 38/130 (29%), Positives = 60/130 (46%), Gaps = 6/130 (4%)
 Frame = +2

Query: 199 EENGTQESR------ISPYTFCKAFPFHIIFDRNLVVTQCGNAIYRVLPQLQPGNCSLLS 252
           E+ GT + R      +    FC AFP+HI+FD NL + QCG+ I R+             
Sbjct: 65  EQRGTPDGRDFSDSVLKAEDFCSAFPYHIVFDENLGIRQCGDNIRRITQVTITDGLPFSR 244

Query: 253 VFSLVRPHIDISFHGILSHINTVFVLRSKEGLLDVEKLECEDELTGAEISCLRLKGQMIY 312
           + ++V+P ++ +   I   IN VF+L       D ++                LKGQMI+
Sbjct: 245 IGNIVQPVMNQTMENIFKFINAVFLLAIHRKPGDGDR-------------PFILKGQMIW 385

Query: 313 LPEADSILFL 322
           L  +  +LF+
Sbjct: 386 LKNSRMMLFI 415
>09572
          Length = 1081

 Score = 42.4 bits (98), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 24/64 (37%), Positives = 36/64 (56%)
 Frame = -1

Query: 532  VIGQRMPRYCLFGNTVNLTSRTETTGEKGKINVSEYTYRCLMSPENSDPLFHLEHRGPVS 591
            VIG     Y ++G+TVN+ SR  +TGE  +I V + T   L      + +F  E+RG + 
Sbjct: 1081 VIGTTKLLYDIWGDTVNIASRMYSTGEPDRIQVPQSTLPKL------EEMFEFEYRGEIM 920

Query: 592  MKGK 595
            +KGK
Sbjct: 919  VKGK 908
>13236
          Length = 449

 Score = 29.3 bits (64), Expect = 4.7,   Method: Compositional matrix adjust.
 Identities = 25/71 (35%), Positives = 35/71 (49%), Gaps = 3/71 (4%)
 Frame = -3

Query: 341 SDIPLHDATRDLVLLGEQFREEYK---LTQELEILTDRLQLTLRALEDEKKKTDTLLYSV 397
           SD  L + TRDL  LGE  R+ Y+    ++E++ L    +L L    D   + DT   SV
Sbjct: 267 SDQRLDEITRDLFPLGETERDHYQDKTYSREIKCLC---RLPLPGQPDSPHRVDTKQRSV 97

Query: 398 LPPSVANELRH 408
             P    +LRH
Sbjct: 96  --PEFVRDLRH 70
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|12963791|ref|NP_076186.1| alcohol dehydrogenase PAN2
[Mus musculus]
         (334 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

26417                                                                 136   9e-33
27168                                                                  89   2e-18
03060                                                                  54   9e-08
03983                                                                  44   7e-05
30930                                                                  40   0.001
11922                                                                  40   0.001
05690                                                                  38   0.005
35613                                                                  34   0.071
07400                                                                  33   0.13 
12758                                                                  33   0.20 
05235                                                                  32   0.50 
33735                                                                  30   1.3  
23588                                                                  28   6.2  
28229                                                                  28   6.5  
12867                                                                  27   9.2  
>26417
          Length = 929

 Score =  136 bits (343), Expect(2) = 9e-33,   Method: Compositional matrix adjust.
 Identities = 79/178 (44%), Positives = 108/178 (60%), Gaps = 3/178 (1%)
 Frame = +1

Query: 131 EPRLDVLINNAGVFHCPYTKTEDGFEMQFGVXXXXXXXXXXXXXXXXKSSAPSRIVVVSS 190
           E R+D+LINNAGV   PY  TEDG E  F                  KSSAPSRI+ VSS
Sbjct: 1   EDRVDILINNAGVIGLPYALTEDGLETNFATNHFGPFLLTNLLLDKLKSSAPSRIINVSS 180

Query: 191 KLYKYGEINFEDLNSEQSYNKSFCYSRSKLANILFTRELARRLEG---TNVTVNVLHPGI 247
            + K G+I+ ++L +E+ + +   Y  SKLAN+LFTRELARRL     T+VTV+ LHPG 
Sbjct: 181 VVQKAGKIDLDNLKAEKYFKEHKIYFNSKLANVLFTRELARRLVATGVTDVTVHCLHPGS 360

Query: 248 VRTNLGRHIHIPLLARPLFNLVSWAFFKTPLEGAQTSIYLACSPDVEGVSGRYFGDCK 305
            +T+L    ++P   R    LV   F  +PLEGAQT+++ A + +V+ +SG+YF  C+
Sbjct: 361 XKTDLLN--NMPWYVRYGMKLVR-VFLLSPLEGAQTTLFCAMAEEVKDMSGKYFAQCQ 525

 Score = 21.2 bits (43), Expect(2) = 9e-33,   Method: Compositional matrix adjust.
 Identities = 8/16 (50%), Positives = 11/16 (68%)
 Frame = +3

Query: 311 PKAMDESVARKLWDIS 326
           P A D  + ++LWDIS
Sbjct: 546 PLANDLDLCKQLWDIS 593
>27168
          Length = 665

 Score = 89.0 bits (219), Expect = 2e-18,   Method: Compositional matrix adjust.
 Identities = 57/166 (34%), Positives = 81/166 (48%)
 Frame = +3

Query: 42  MHGKTVLITGANSGLGRATAAELLRLGARVIMGCRDRARAEEAAGQLRQELCQAGGAGPD 101
           +HG+  LITGAN G+G  TA  L   G  +I+ CR+ A A+EA  ++  E   A      
Sbjct: 180 LHGRVALITGANCGIGFETARSLALHGCEIILACRNLATAQEAIDRIAVERPAARARCRT 359

Query: 102 GTDGQLVVKELDLASLRSVRAFCQELLQEEPRLDVLINNAGVFHCPYTKTEDGFEMQFGV 161
            +        LDL SL  V+ F +++ Q    +D LI NAGVF  PYTKT DG E  F V
Sbjct: 360 AS--------LDLGSLSDVKKFVEQIRQSVGHIDYLILNAGVFALPYTKTVDGLETTFQV 515

Query: 162 XXXXXXXXXXXXXXXXKSSAPSRIVVVSSKLYKYGEINFEDLNSEQ 207
                                +RIVV+SS+ +++  +  E+L  + 
Sbjct: 516 SHLSHFYLTLQLESLFDHR--TRIVVLSSESHRFASLPVENLTVQH 647
>03060
          Length = 1893

 Score = 53.9 bits (128), Expect = 9e-08,   Method: Compositional matrix adjust.
 Identities = 57/213 (26%), Positives = 90/213 (42%), Gaps = 2/213 (0%)
 Frame = -1

Query: 42   MHGKTVLITGANSGLGRATAAELLRLGARVIMGCRDRARAEEAAGQLRQELCQAGGAGPD 101
            + GK VL+TGA+SGLG+A A    + G +VI+  R   R       L +   +     P 
Sbjct: 1695 IQGKVVLVTGASSGLGKACAKVFHQHGCQVILAGRSVERLNAVKDYLTKSEGEVKACEPS 1516

Query: 102  GTDGQLVVKELDLASLRSVRAFCQELLQEEPRLDVLINNAGVFH--CPYTKTEDGFEMQF 159
                   V  +DL  L S++   +  ++   ++DV+INNAG+ +  C    +    +   
Sbjct: 1515 -------VLAMDLEDLNSLQQLAERAVELFGKVDVVINNAGISYRGCIEDTSIQVDQKLM 1357

Query: 160  GVXXXXXXXXXXXXXXXXKSSAPSRIVVVSSKLYKYGEINFEDLNSEQSYNKSFCYSRSK 219
             V                ++     IV +SS     G+I+         Y  +  YS SK
Sbjct: 1356 AVNYFGHVALIKGLLPHMQARNSGHIVGISS---VQGKISIP-------YRSA--YSASK 1213

Query: 220  LANILFTRELARRLEGTNVTVNVLHPGIVRTNL 252
             A   F   L   L  T + V++L PG ++TNL
Sbjct: 1212 HALQAFFDCLRAELSCTKIKVSLLSPGYIKTNL 1114
>03983
          Length = 1099

 Score = 44.3 bits (103), Expect = 7e-05,   Method: Compositional matrix adjust.
 Identities = 55/238 (23%), Positives = 89/238 (37%), Gaps = 12/238 (5%)
 Frame = +2

Query: 42  MHGKTVLITGANSGLGRATAAELLRLGARVIMGCRDRARAEEAAGQLRQEL-CQAGGAGP 100
           + G+ VLITGA SGLG+  A   + LG  +++   +    E     + Q++ C+A     
Sbjct: 170 VEGQRVLITGAGSGLGKLMAYRFMGLGCDLVLWDINTEAIEAMERDMGQQVSCKA----- 334

Query: 101 DGTDGQLVVKELDLASLRSVRAFCQELLQEEPRLDVLINNAGV------FHCPYTKTEDG 154
                      +DL+S   +     ++ +E   +D+L+NNAG+        CP +  E  
Sbjct: 335 ---------YTVDLSSREQIYKAADQVKREVGGVDILVNNAGIVTGRKFLDCPDSLIEKT 487

Query: 155 FEMQFGVXXXXXXXXXXXXXXXXKSSAPSRIVVVSSKLYKYGEINFEDLNSEQSYNKSFC 214
            E+                    K      I+ ++S    +G     D            
Sbjct: 488 MEVNSNAHFWTVKAFLPNMLAQNK----GHIISIASSAGLFGVTGLAD------------ 619

Query: 215 YSRSKLANILFTRELARRLEG---TNVTVNVLHPGIVRTNL--GRHIHIPLLARPLFN 267
           Y  SK A + F   L   LE    T V   V+ P  + T +  G     PL+  P+ N
Sbjct: 620 YCASKFAAVGFDESLRFELEAMGKTGVHTTVVCPYFINTGMFDGVKTRFPLIL-PILN 790
>30930
          Length = 1452

 Score = 40.4 bits (93), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 37/105 (35%), Positives = 46/105 (43%), Gaps = 3/105 (2%)
 Frame = -3

Query: 44   GKTVLITGANSGLGRATAAELLRLGARVIMGCRDRARAEEAAGQLRQELCQAGGAGPDGT 103
            GK VLITG + G G  +A  L  LG RV  GC D     E A QLR             T
Sbjct: 1357 GKAVLITGCDRGFGFLSAQRLSSLGYRVFAGCFD--ATGEGAAQLRL------------T 1220

Query: 104  DGQLVVKELDLAS---LRSVRAFCQELLQEEPRLDVLINNAGVFH 145
               + V +LD+ +   +   R F  E LQ    L  ++NNAG   
Sbjct: 1219 SPNIDVIQLDVTNDGQVEEARRFXDEQLQGYG-LWAIVNNAGTLF 1088
>11922
          Length = 2153

 Score = 40.0 bits (92), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 27/102 (26%), Positives = 51/102 (50%)
 Frame = +1

Query: 40  GLMHGKTVLITGANSGLGRATAAELLRLGARVIMGCRDRARAEEAAGQLRQELCQAGGAG 99
           G + GKTV ITGA+ G+G+A A +L + GA +++  +      +  G +     +   AG
Sbjct: 88  GKLVGKTVFITGASRGIGKAIAVKLAKDGANIVIAAKTAEAHPKLPGTIYTAAKEVEEAG 267

Query: 100 PDGTDGQLVVKELDLASLRSVRAFCQELLQEEPRLDVLINNA 141
                G+ +   +D+ +   V+   +    +   +D+L+NNA
Sbjct: 268 -----GKALPCIVDIRNEDQVKVAVKAAADKFGGIDILVNNA 378
>05690
          Length = 1192

 Score = 38.1 bits (87), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 31/106 (29%), Positives = 44/106 (41%), Gaps = 4/106 (3%)
 Frame = +2

Query: 44  GKTVLITGANSGLGRATAAELLRLGARVIMGCRDRARAEEAA--GQLRQELCQAGGAGPD 101
           GK V ITG ++GLG   A  L +LG +V  GC       E     +  Q LC        
Sbjct: 173 GKAVFITGCDAGLGHLLAIHLDKLGVKVFAGCLFPGGEGEQTLKAKCSQRLCTV------ 334

Query: 102 GTDGQLVVKELDLASLRSVRAFCQELLQEEPRLDV--LINNAGVFH 145
                     LD+ SL  V      + +E    ++  ++NNAG+ H
Sbjct: 335 ---------PLDVCSLEIVTTAADTVKRELDGQELWGVVNNAGIMH 445
>35613
          Length = 977

 Score = 34.3 bits (77), Expect = 0.071,   Method: Compositional matrix adjust.
 Identities = 37/116 (31%), Positives = 50/116 (43%), Gaps = 2/116 (1%)
 Frame = +1

Query: 29  RNQRQQGGGDPGLMHGKTVLITGANSGLGRATAAELLRLGARVIMGCRDRARAEEAAGQL 88
           R  R+   G   L   KTVLITG ++G G A A  L   G  VI      A   +  G  
Sbjct: 43  RRHRRAAAGSVCL-RDKTVLITGCDTGFGHALAKSLHEDGCHVI------ATVYQPDGDG 201

Query: 89  RQELCQAGGAGPDGTDGQLVVKELDLASLRSVRAFCQELLQ--EEPRLDVLINNAG 142
            + L        D +  ++ V  LD++S  SV    + + Q  E   L  L+NNAG
Sbjct: 202 AKRL-------RDVSTDRMTVIPLDVSSDDSVEKCLRHVKQLCEHSGLWGLVNNAG 348
>07400
          Length = 1577

 Score = 33.5 bits (75), Expect = 0.13,   Method: Compositional matrix adjust.
 Identities = 32/100 (32%), Positives = 44/100 (44%), Gaps = 2/100 (2%)
 Frame = -3

Query: 45   KTVLITGANSGLGRATAAELLRLGARVIMGCRDRARAEEAAGQLRQELCQAGGAGPDGTD 104
            K VLITG ++G+G   A E  + G  V+ GC D   +        Q L +  G       
Sbjct: 1437 KVVLITGCDTGIGHEAALEANKRGLTVVAGCLDVTSSGA------QRLAEKKGVH----- 1291

Query: 105  GQLVVKELDLASLRSVRAFCQEL--LQEEPRLDVLINNAG 142
                V  LD++S  SV    + +  L E   L  +INNAG
Sbjct: 1290 ----VIRLDVSSDESVANAMKSVSKLCEAKGLWAVINNAG 1183
>12758
          Length = 804

 Score = 32.7 bits (73), Expect = 0.20,   Method: Compositional matrix adjust.
 Identities = 38/165 (23%), Positives = 65/165 (39%), Gaps = 3/165 (1%)
 Frame = -1

Query: 93  CQAGGAGPDGTDGQLVVKELDLASLRSVRAFCQELLQEEPRLDVLINNAGVFHCPYTKTE 152
           C AGG  P    G       DL      +   +E +++  RL++L+N AG+      +  
Sbjct: 756 C*AGGQKPLLLVG-------DLTKEDDTKRVVEETVKQFGRLNILVNCAGIIELGNIENT 598

Query: 153 --DGFEMQFGVXXXXXXXXXXXXXXXXKSSAPSRIVVVSSKLYKYGEI-NFEDLNSEQSY 209
             D ++  F                  +S     ++ V   +   G I N   +N  +S+
Sbjct: 597 SLDQYDRMFNT--------------NVRSVYHLTMLAVPHLVNTQGNIVNVSSVNGMRSF 460

Query: 210 NKSFCYSRSKLANILFTRELARRLEGTNVTVNVLHPGIVRTNLGR 254
                Y  +K A   FTR +A  L    V VN ++PG++ + L +
Sbjct: 459 PNVLAYCMAKSAIDQFTRCVALELAPKKVRVNGVNPGVIISELQK 325
>05235
          Length = 944

 Score = 31.6 bits (70), Expect = 0.50,   Method: Compositional matrix adjust.
 Identities = 21/61 (34%), Positives = 28/61 (45%), Gaps = 10/61 (16%)
 Frame = -2

Query: 214 CYSRSKLANILFTRELARRLEGTNVTVNVLHPGIVRT----------NLGRHIHIPLLAR 263
            YS SK   + FT  LA+    T VTV  ++PGI  T          ++  H+   LLA 
Sbjct: 436 VYSASKAXALSFTNSLAKLAHITGVTVYSINPGITHTPLVNKFNSWLDVESHVAEKLLAN 257

Query: 264 P 264
           P
Sbjct: 256 P 254
>33735
          Length = 248

 Score = 30.0 bits (66), Expect = 1.3,   Method: Composition-based stats.
 Identities = 18/57 (31%), Positives = 30/57 (52%), Gaps = 3/57 (5%)
 Frame = -3

Query: 30  NQRQQGGGDPGLMHGKTVLITGANSGLGRATAAELLRLGAR---VIMGCRDRARAEE 83
           NQ+++    P     +TV ITGA+ GLG      +L   ++   +   CR+ +RA+E
Sbjct: 171 NQKEKSTMSP-----QTVFITGASRGLGLEFVKHILAQPSKPQLLFAACRNPSRADE 16
>23588
          Length = 611

 Score = 27.7 bits (60), Expect = 6.2,   Method: Compositional matrix adjust.
 Identities = 30/106 (28%), Positives = 44/106 (41%)
 Frame = +3

Query: 56  LGRATAAELLRLGARVIMGCRDRARAEEAAGQLRQELCQAGGAGPDGTDGQLVVKELDLA 115
           +G   A  L   GAR+ +  RD  + E    +     C A G  P  TD   V  +L   
Sbjct: 3   IGAGIAVCLGERGARLSLTGRDATKLENVVQK-----CVAAGVKP--TDVVTVAGDLTDE 161

Query: 116 SLRSVRAFCQELLQEEPRLDVLINNAGVFHCPYTKTEDGFEMQFGV 161
           + R  +      + +  ++DVL+NNAG F  P   ++ G E    V
Sbjct: 162 TFR--QQLVASTVDKFGQIDVLVNNAG-FANPGLLSBPGMENLLNV 290
>28229
          Length = 633

 Score = 27.7 bits (60), Expect = 6.5,   Method: Compositional matrix adjust.
 Identities = 10/23 (43%), Positives = 15/23 (65%)
 Frame = -2

Query: 122 AFCQELLQEEPRLDVLINNAGVF 144
           A  Q+ +    R+DVL+NNAG+ 
Sbjct: 458 AIIQQTINHYGRIDVLVNNAGIL 390
>12867
          Length = 858

 Score = 27.3 bits (59), Expect = 9.2,   Method: Compositional matrix adjust.
 Identities = 13/36 (36%), Positives = 21/36 (58%)
 Frame = -3

Query: 107 LVVKELDLASLRSVRAFCQELLQEEPRLDVLINNAG 142
           ++V  +D+  L   ++    +L    RLDVL+NNAG
Sbjct: 793 VLVLPMDMLQLEEHQSHLYTVLNHFDRLDVLVNNAG 686
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|21704162|ref|NP_663553.1| ubiquitin-conjugating
enzyme E2M [Mus musculus]
         (183 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

29762                                                                  93   9e-33
02183                                                                 114   3e-26
31099                                                                  98   2e-21
21443                                                                  95   2e-20
37111                                                                  82   1e-16
18592                                                                  81   2e-16
02740                                                                  79   1e-15
14380                                                                  78   2e-15
38163                                                                  73   8e-14
34525                                                                  71   3e-13
39424                                                                  62   5e-12
13254                                                                  63   5e-11
02313                                                                  59   1e-09
19311                                                                  58   2e-09
04905                                                                  55   2e-08
12485                                                                  54   4e-08
05633                                                                  53   8e-08
21913                                                                  38   0.002
34541                                                                  35   0.015
10963                                                                  30   0.38 
04034                                                                  30   0.43 
09704                                                                  30   0.49 
>29762
          Length = 460

 Score = 93.2 bits (230), Expect(2) = 9e-33,   Method: Compositional matrix adjust.
 Identities = 43/48 (89%), Positives = 44/48 (91%)
 Frame = -1

Query: 136 FLEPNPEDPLNKEAAEVLQNNRRLFEQNVQRSMRGGYIGSTYFERCLK 183
           FLEPNPEDPLNKEAAEVLQ NRRLFEQNV +SMRGG IGS YFERCLK
Sbjct: 343 FLEPNPEDPLNKEAAEVLQTNRRLFEQNVSKSMRGGAIGSLYFERCLK 200

 Score = 63.5 bits (153), Expect(2) = 9e-33,   Method: Compositional matrix adjust.
 Identities = 26/37 (70%), Positives = 30/37 (81%)
 Frame = -2

Query: 102 PNIDLEGNVCLNILREDWKPVLTINSIIYGLQYLFLE 138
             +  +GNVCLNILREDWKPVLT+NSI+YGLQY F  
Sbjct: 444 STLTWKGNVCLNILREDWKPVLTVNSIVYGLQYRFWS 334
>02183
          Length = 1456

 Score =  114 bits (285), Expect = 3e-26,   Method: Compositional matrix adjust.
 Identities = 60/174 (34%), Positives = 99/174 (56%), Gaps = 12/174 (6%)
 Frame = -2

Query: 4    LFSLKQQKKEEESAGGTKGSSKKASAAQLR---IQKDINEL--NLPKTCDISFSDPDDLL 58
            + +L ++ K++ +AG  K +  ++    +R   + K++ E+  N+P+TC + F DP  L 
Sbjct: 1377 MITLSKKLKQQTTAGPKKDAEPESRRISIRDKLLVKEVQEMEENMPRTCKVQFDDPSVLH 1198

Query: 59   NFKLVICPDEGFYKSGKFVFSFKVGQGYPHDPPKVKCETMVYHPNIDLEGNVCLNILRED 118
            +F L + PDEG++  GKF F   V + Y   PPK  C T ++HPNI   G +CL++LR++
Sbjct: 1197 HFILNVTPDEGYWTGGKFKFDINVPEEYNIVPPKAVCHTKIWHPNITEAGEICLSLLRQN 1018

Query: 119  ------WKPVLTINSIIYGLQYLFLE-PNPEDPLNKEAAEVLQNNRRLFEQNVQ 165
                  W P   +  +++GL  LF +  N EDPLN EAAE    ++  F+  V+
Sbjct: 1017 SYDGLGWAPTRRLKDVVWGLNSLFSDLLNFEDPLNVEAAEHFARDKESFKIKVR 856
>31099
          Length = 748

 Score = 97.8 bits (242), Expect = 2e-21,   Method: Compositional matrix adjust.
 Identities = 44/109 (40%), Positives = 65/109 (59%), Gaps = 1/109 (0%)
 Frame = +2

Query: 55  DDLLNFKLVIC-PDEGFYKSGKFVFSFKVGQGYPHDPPKVKCETMVYHPNIDLEGNVCLN 113
           DD  +++  I  P++  Y+ G F  +      YP  PPKV   T +YHPNI+  G++CL+
Sbjct: 173 DDFFHWQATIMGPNKSPYQGGVFFLTITFPADYPFKPPKVAFTTKIYHPNINSNGSICLD 352

Query: 114 ILREDWKPVLTINSIIYGLQYLFLEPNPEDPLNKEAAEVLQNNRRLFEQ 162
           ILR  W P LTI+ ++  +  L  +PNP+DPL  E A V +N+R  +EQ
Sbjct: 353 ILRSQWSPALTISKVLLSISSLLTDPNPDDPLVPEIARVYKNDRHKYEQ 499
>21443
          Length = 610

 Score = 95.1 bits (235), Expect = 2e-20,   Method: Compositional matrix adjust.
 Identities = 47/147 (31%), Positives = 75/147 (51%), Gaps = 2/147 (1%)
 Frame = -1

Query: 21  KGSSKKASAAQLRIQKDINEL--NLPKTCDISFSDPDDLLNFKLVICPDEGFYKSGKFVF 78
           K + +    A  RI K++ +L  + P  C       D       ++ P +  Y+ G F  
Sbjct: 559 KRTHRTFKMAMKRINKELQDLGKDPPAQCSAGPVGEDMFQWQATIMGPRDSAYEGGVFFL 380

Query: 79  SFKVGQGYPHDPPKVKCETMVYHPNIDLEGNVCLNILREDWKPVLTINSIIYGLQYLFLE 138
           +      YP  PPKV   T +YHPNI+  G++CL+ILR  W P LTI+ ++  +  +  +
Sbjct: 379 TISFPTDYPFKPPKVSFTTRIYHPNINSNGSICLDILRSQWSPALTISKVLLSICSMLTD 200

Query: 139 PNPEDPLNKEAAEVLQNNRRLFEQNVQ 165
           PNP+DPL  E A + + +R  F +N +
Sbjct: 199 PNPDDPLVPEIARIYKTDREKFYENAK 119
>37111
          Length = 611

 Score = 82.0 bits (201), Expect = 1e-16,   Method: Compositional matrix adjust.
 Identities = 43/151 (28%), Positives = 83/151 (54%), Gaps = 8/151 (5%)
 Frame = -1

Query: 24  SKKASAAQLRIQKDINELNLPKTCDISFSDPD-DLLNFKL------VICPDEGFYKSGKF 76
           S+ A+ AQ RIQ++  E+   K+ +++ +    D ++  L      ++ P E  Y+ G+F
Sbjct: 509 SRMANIAQQRIQREFKEVV--KSAEVTQAAIKVDFVDGMLTHLKGEIMGPPETPYEGGRF 336

Query: 77  VFSFKVGQGYPHDPPKVKCETMVYHPNID-LEGNVCLNILREDWKPVLTINSIIYGLQYL 135
               ++ + YP +PP VK  T ++HPN+  + G +CL+IL++ W   +T+ +++  LQ L
Sbjct: 335 ELDIRIPETYPFNPPLVKFLTKIWHPNVSSVTGAICLDILKDQWAAAMTLRTVLLSLQAL 156

Query: 136 FLEPNPEDPLNKEAAEVLQNNRRLFEQNVQR 166
                P+DP +   A   +++R LF +  + 
Sbjct: 155 MAAAEPDDPQDAVVANQYKDHRELFNKTARH 63
>18592
          Length = 475

 Score = 81.3 bits (199), Expect = 2e-16,   Method: Compositional matrix adjust.
 Identities = 46/127 (36%), Positives = 66/127 (51%), Gaps = 4/127 (3%)
 Frame = +2

Query: 29  AAQLRIQK---DINELNLPKTCDISFSDPDDLLNFKLVICPDEGFYKSGKFVFSFKVGQG 85
           AA  R+ K   DI +    K   I   D  ++L++++V+ P+   Y  G F         
Sbjct: 89  AATRRLTKELQDIRKEASQKAFRIKDQDESNILHWEVVLVPENPPYNKGTFTVDINFPAE 268

Query: 86  YPHDPPKVKCETMVYHPNIDLEGNVCLNILR-EDWKPVLTINSIIYGLQYLFLEPNPEDP 144
           YP  PPKV  +T +YHPN+D +G VCL I+  E+WKP    + ++  L  L  EP PE P
Sbjct: 269 YPFKPPKVTFKTKIYHPNVDEKGQVCLPIISAENWKPATKTDQVLTALIGLINEPEPEHP 448

Query: 145 LNKEAAE 151
           L  + AE
Sbjct: 449 LRADLAE 469
>02740
          Length = 2287

 Score = 78.6 bits (192), Expect = 1e-15,   Method: Compositional matrix adjust.
 Identities = 42/136 (30%), Positives = 72/136 (52%), Gaps = 2/136 (1%)
 Frame = -1

Query: 33   RIQKDINELNLPKTCDIS-FSDPDDLLNFKLVICPDEG-FYKSGKFVFSFKVGQGYPHDP 90
            R+Q+++  L +     +S F D D+L  +   I   +G  Y+  ++    +   GYP+  
Sbjct: 1993 RLQQELRTLMMSSDPGVSAFPDGDNLFKWVGTIEGAKGTVYEGLQYKLVLEFPSGYPYQA 1814

Query: 91   PKVKCETMVYHPNIDLEGNVCLNILREDWKPVLTINSIIYGLQYLFLEPNPEDPLNKEAA 150
              V+  T  +HPN+D  GN+CL+IL+E W  +  + +++  +Q L  EPN   PLN  AA
Sbjct: 1813 VSVRFSTPCFHPNVDNHGNICLDILKEKWSALYDVRTVLLSIQSLLAEPNNVSPLNXHAA 1634

Query: 151  EVLQNNRRLFEQNVQR 166
            E+ +N     E  +Q+
Sbjct: 1633 ELWKNQDAYKEYLLQK 1586
>14380
          Length = 1522

 Score = 78.2 bits (191), Expect = 2e-15,   Method: Compositional matrix adjust.
 Identities = 41/121 (33%), Positives = 64/121 (52%), Gaps = 1/121 (0%)
 Frame = +3

Query: 51  FSDPDDLLNFKLVI-CPDEGFYKSGKFVFSFKVGQGYPHDPPKVKCETMVYHPNIDLEGN 109
           F++ +D+ + +  I  P    Y  G F     + + +P +PPK    T ++HPN+   G 
Sbjct: 180 FTNDEDITDIQATIEGPAGTPYAGGLFRMKLVLSKSFPSEPPKAFFITKIFHPNVASNGE 359

Query: 110 VCLNILREDWKPVLTINSIIYGLQYLFLEPNPEDPLNKEAAEVLQNNRRLFEQNVQRSMR 169
           +C+N L+ DWKP L I  I+  ++ L + PNPE  LN+EA ++      L EQ    SMR
Sbjct: 360 ICVNTLKRDWKPELGIKHILLTVKCLLIVPNPESALNEEAGKL------LLEQYEDYSMR 521

Query: 170 G 170
            
Sbjct: 522 A 524
>38163
          Length = 2214

 Score = 72.8 bits (177), Expect = 8e-14,   Method: Compositional matrix adjust.
 Identities = 42/119 (35%), Positives = 60/119 (50%), Gaps = 6/119 (5%)
 Frame = -3

Query: 53   DPDDLLNFKLVICPDEG----FYKSGKFVFSFKVGQGYPHDPPKVKCETMVYHPNIDLEG 108
            +PD  LN     C   G     ++ G F       + YP  PPK K E  ++HPN+   G
Sbjct: 1696 NPDGTLNLFNWECKIPGKKGTMWEGGLFSLRMLFKEDYPSTPPKCKFEPPLFHPNVYPSG 1517

Query: 109  NVCLNILRE--DWKPVLTINSIIYGLQYLFLEPNPEDPLNKEAAEVLQNNRRLFEQNVQ 165
             VCL++L E  DW+P +TI  I+ G+Q L  E N +DP   EA  +   N   +E+ V+
Sbjct: 1516 TVCLSLLDEEKDWRPAVTIKQILLGIQELLNECNVKDPAQAEAYTIYCQNSSEYERRVR 1340
>34525
          Length = 561

 Score = 70.9 bits (172), Expect = 3e-13,   Method: Compositional matrix adjust.
 Identities = 35/92 (38%), Positives = 52/92 (56%), Gaps = 5/92 (5%)
 Frame = -1

Query: 86  YPHDPPKVKCETMVYHPNIDLEGNVCLNILRED----WKPVLTINSIIYGLQYLFLEPNP 141
           YP +PPKV+  T +YHPNID  G +CL+ L+      WKP + + +++  LQ L   PNP
Sbjct: 360 YPFEPPKVQFTTPIYHPNIDNAGRICLDTLKMPPKGAWKPCMNLMTVLTSLQLLMATPNP 181

Query: 142 EDPLNKEAAEVLQNNRRLFEQN-VQRSMRGGY 172
           +D L  + A   ++   LF Q  VQ + +  Y
Sbjct: 180 DDALMADIASEFKHTPELFRQKAVQFTKQHAY 85
>39424
          Length = 1749

 Score = 61.6 bits (148), Expect(2) = 5e-12,   Method: Compositional matrix adjust.
 Identities = 32/97 (32%), Positives = 52/97 (53%), Gaps = 13/97 (13%)
 Frame = -2

Query: 91   PKVKCETMVYHPNIDLEGNVCLNILRED-------------WKPVLTINSIIYGLQYLFL 137
            PK+K  + ++HPNID EGNVC++IL E              W P+ T+ +I+  +  +  
Sbjct: 1490 PKMKFVSEMWHPNIDPEGNVCISILHEPGDDKYGYEKASERWLPIHTVETILVSVISMLA 1311

Query: 138  EPNPEDPLNKEAAEVLQNNRRLFEQNVQRSMRGGYIG 174
            +PN E P N +AA++ +     F++ V R +R    G
Sbjct: 1310 DPNDESPANVDAAKMWREQPEEFKKRVSRCVRRSQDG 1200

 Score = 25.0 bits (53), Expect(2) = 5e-12,   Method: Compositional matrix adjust.
 Identities = 19/64 (29%), Positives = 31/64 (48%), Gaps = 3/64 (4%)
 Frame = -1

Query: 32   LRIQKDINELNLPKTCDIS--FSDPDDLLNFKLVI-CPDEGFYKSGKFVFSFKVGQGYPH 88
            L ++K + EL+   T   S    D DD+  ++++I  P E  +  G F       + YP+
Sbjct: 1677 LLLRKQLAELSKSGTEGFSAGLIDDDDVYKWEVLIYGPPETLFDGGYFKAHLIFPKEYPN 1498

Query: 89   DPPK 92
             PPK
Sbjct: 1497 RPPK 1486
>13254
          Length = 870

 Score = 63.2 bits (152), Expect = 5e-11,   Method: Compositional matrix adjust.
 Identities = 25/57 (43%), Positives = 39/57 (68%)
 Frame = +2

Query: 97  TMVYHPNIDLEGNVCLNILREDWKPVLTINSIIYGLQYLFLEPNPEDPLNKEAAEVL 153
           T ++HPN+   G +C+N L++DWKP L I  I+  ++ L + PNPE  LN+EA ++L
Sbjct: 188 TKIFHPNVASNGEICVNTLKKDWKPDLGIKHILLTIKCLLIVPNPESALNEEAGKML 358
>02313
          Length = 891

 Score = 58.9 bits (141), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 33/110 (30%), Positives = 52/110 (47%), Gaps = 14/110 (12%)
 Frame = -1

Query: 55  DDLLNFKLVI-CPDEGFYKSGKFVFSFKVGQGYPHDPPKVKCETMVYHPNIDLEGNVCLN 113
           D++  +++ I  P    Y+ G F    K    YP+ PP V+  T ++HPN+   G VC++
Sbjct: 684 DNIFEWEVAIFGPPGTLYEGGYFKAHMKFPADYPYSPPSVRFITKMWHPNVYENGEVCIS 505

Query: 114 ILR-------------EDWKPVLTINSIIYGLQYLFLEPNPEDPLNKEAA 150
           IL              E W P  T+ +I+  +  L  EPN   P N +A+
Sbjct: 504 ILHPPVDDPQSGELPSERWNPTQTVRTILLSIISLLNEPNTYSPANVDAS 355
>19311
          Length = 1071

 Score = 58.2 bits (139), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 27/95 (28%), Positives = 49/95 (51%)
 Frame = -2

Query: 72  KSGKFVFSFKVGQGYPHDPPKVKCETMVYHPNIDLEGNVCLNILREDWKPVLTINSIIYG 131
           K G F+   ++   YP  PPKV+  T ++HPNI   G+V L+ +  +W   LTI+ ++  
Sbjct: 464 KGGWFLLYLQIPHSYPMRPPKVRFITKIFHPNISRHGDVGLDSIHHNWSLALTISKVLIS 285

Query: 132 LQYLFLEPNPEDPLNKEAAEVLQNNRRLFEQNVQR 166
           +Q +  +P     +  +   + Q  +  FE+  +R
Sbjct: 284 IQSVLTDPYCHVCMEPKIGALYQRAKPEFERIARR 180
>04905
          Length = 1868

 Score = 54.7 bits (130), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 29/101 (28%), Positives = 53/101 (52%), Gaps = 2/101 (1%)
 Frame = -1

Query: 71   YKSGKFVFSFKVGQGYPHDPPKVKCETMVYHPNID-LEGNVCLNILREDWKPVLTINSII 129
            Y+ G +     + + YP   P +     +YHPNID + G VCL+++ + W  +  +++I 
Sbjct: 1646 YEGGVWKVRVDLPERYPFKSPSIGFINRIYHPNIDEVSGTVCLDVINQAWTALYDLSNIF 1467

Query: 130  YG-LQYLFLEPNPEDPLNKEAAEVLQNNRRLFEQNVQRSMR 169
               L  L   PNP DPLN +AA +  +    +++ V+  ++
Sbjct: 1466 ESFLPQLLTYPNPVDPLNGDAAALYLHRPDEYKKKVEEYVQ 1344
>12485
          Length = 652

 Score = 53.5 bits (127), Expect = 4e-08,   Method: Compositional matrix adjust.
 Identities = 29/98 (29%), Positives = 50/98 (51%), Gaps = 2/98 (2%)
 Frame = +1

Query: 71  YKSGKFVFSFKVGQGYPHDPPKVKCETMVYHPNID-LEGNVCLNILREDWKPVLTINSII 129
           Y+ G +     + + YP   P +     +YHPNID + G VCL+++ + W  +  +++I 
Sbjct: 49  YEGGVWKVRVDLPEKYPFKSPSIGFMNRIYHPNIDEVSGTVCLDVINQAWTALYDLSNIF 228

Query: 130 YG-LQYLFLEPNPEDPLNKEAAEVLQNNRRLFEQNVQR 166
              L  L   PNP DPLN +AA +  +    +++   R
Sbjct: 229 ESFLPQLLTYPNPIDPLNGDAAALYLHKPEDYKKKSSR 342
>05633
          Length = 1150

 Score = 52.8 bits (125), Expect = 8e-08,   Method: Compositional matrix adjust.
 Identities = 24/61 (39%), Positives = 35/61 (57%), Gaps = 2/61 (3%)
 Frame = +3

Query: 70  FYKSGKFVFSFKVGQGYPHDPPKVKC--ETMVYHPNIDLEGNVCLNILREDWKPVLTINS 127
            Y+  KF   FK G  YP D P+V      +  HP++   G++CL+IL EDW P L++ S
Sbjct: 78  LYEGEKFQLHFKFGAKYPFDSPQVTFLGPNIPIHPHVYSNGHICLSILTEDWSPALSVQS 257

Query: 128 I 128
           +
Sbjct: 258 V 260
>21913
          Length = 874

 Score = 38.1 bits (87), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 29/109 (26%), Positives = 50/109 (45%), Gaps = 5/109 (4%)
 Frame = +3

Query: 68  EGFYKSGKFVFSFKVGQGYPH-DPPKVKCETMVYHPNID-LEGNVCLNILREDWKPVLTI 125
           +G Y+     F+  +   YP  D P +  E  V+HP +D + G V +      W+    +
Sbjct: 144 QGLYEGCSLRFTLTIPDNYPDGDCPDLVFEFPVFHPLVDPVSGKVDVKRAFPKWR--RNV 317

Query: 126 NSIIYGLQY---LFLEPNPEDPLNKEAAEVLQNNRRLFEQNVQRSMRGG 171
           N +   L Y   +F +   + PLN EAA + + +   F Q+V  S++  
Sbjct: 318 NHLWQVLMYARKIFYKIETKAPLNPEAATLYEQDTDQFRQHVSESVQTA 464
>34541
          Length = 491

 Score = 35.0 bits (79), Expect = 0.015,   Method: Compositional matrix adjust.
 Identities = 19/68 (27%), Positives = 34/68 (50%), Gaps = 3/68 (4%)
 Frame = +2

Query: 107 EGNVCLNILREDWKPVLTINSIIYGLQYLFLEPNPEDPLNKEAAEVLQNNRRL---FEQN 163
           +G++CL+IL+  W P   +++I+  +Q  F  P           ++ Q   +L   FE+ 
Sbjct: 56  DGSICLDILQNRWSPTYDVSAILTSIQLCFTTPT----------QIAQPTMKLPSCFEK- 202

Query: 164 VQRSMRGG 171
           +  SMR G
Sbjct: 203 IDESMRKG 226

 Score = 34.7 bits (78), Expect = 0.025,   Method: Compositional matrix adjust.
 Identities = 23/73 (31%), Positives = 32/73 (43%), Gaps = 5/73 (6%)
 Frame = +1

Query: 95  CETMVYHPNIDLEGNVCL-----NILREDWKPVLTINSIIYGLQYLFLEPNPEDPLNKEA 149
           C T    P  D   +VC        L E  +P +      Y    L  +PNP  P N EA
Sbjct: 4   CSTPRTLPGADGRTSVCRWQYMPGHLAEQVEPYIRCFRYPYINTALLHDPNPNSPANNEA 183

Query: 150 AEVLQNNRRLFEQ 162
           A++ + NRR +E+
Sbjct: 184 AQLFRENRREYEK 222
>10963
          Length = 569

 Score = 30.4 bits (67), Expect = 0.38,   Method: Compositional matrix adjust.
 Identities = 11/22 (50%), Positives = 18/22 (81%)
 Frame = +3

Query: 96  ETMVYHPNIDLEGNVCLNILRE 117
           +T +YH NI+ +G +CL+IL+E
Sbjct: 498 KTRIYHCNINSQGAICLDILKE 563
>04034
          Length = 1243

 Score = 30.4 bits (67), Expect = 0.43,   Method: Compositional matrix adjust.
 Identities = 15/40 (37%), Positives = 21/40 (52%)
 Frame = +2

Query: 25   KKASAAQLRIQKDINELNLPKTCDISFSDPDDLLNFKLVI 64
            K  S+   +I    + LNL     I +SD D L+NFK V+
Sbjct: 1034 KHKSSVHTQIHIHTHILNLHTVTKIVYSDTDCLINFKYVL 1153
>09704
          Length = 790

 Score = 30.0 bits (66), Expect = 0.49,   Method: Compositional matrix adjust.
 Identities = 23/81 (28%), Positives = 34/81 (41%), Gaps = 11/81 (13%)
 Frame = -1

Query: 61  KLVICPDEGFYKS-GKFVFSFKVGQGYPHDPPKVKCETMVY----------HPNIDLEGN 109
           K V C DEG+ KS G F    K  QG  HD  ++ C   ++           PN+    +
Sbjct: 394 KYVTCSDEGYIKSEGLFAVKLKKKQGNFHDFQRICCLKTLFPKALSNCHYIFPNLYFRRH 215

Query: 110 VCLNILREDWKPVLTINSIIY 130
           V    +R D++      S+ Y
Sbjct: 214 V---TIRTDYRFSSDFRSLCY 161
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|7656912|ref|NP_056618.1| ATPase, aminophospholipid
transporter-like, class I, type 8A, member 2 [Mus musculus]
         (1148 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

26546                                                                 139   9e-33
06342                                                                  70   4e-12
07699                                                                  57   4e-08
00499                                                                  45   2e-04
14321                                                                  43   6e-04
28890                                                                  37   0.044
21541                                                                  36   0.078
03521                                                                  35   0.19 
04985                                                                  33   0.45 
36548                                                                  33   0.79 
00109                                                                  30   6.3  
>26546
          Length = 713

 Score =  139 bits (349), Expect = 9e-33,   Method: Compositional matrix adjust.
 Identities = 67/165 (40%), Positives = 100/165 (60%), Gaps = 1/165 (0%)
 Frame = +1

Query: 140 NGQYLPADMVLFSSSEPQGMCYVETANLDGETNLKIRQGLSHTTDMQTRDVLMK-LSGRI 198
           N  ++ AD+++ S+SEP  +CY+ETA LDGETNLK+RQ L  T +M      M      I
Sbjct: 13  NNDFVAADLMVLSTSEPHSLCYIETAELDGETNLKVRQALEVTAEMADDHAKMAAFDAEI 192

Query: 199 ECEGPNRHLYDFTGNLHLDGKSSVALGPDQILLRGTQLRNTQWVFGVVVYTGHDSKLMQN 258
             E PN  L  F G ++  G++  +L  ++ILLRG  LRNT+W +G+V++ G D+KLM N
Sbjct: 193 VSEPPNNRLSKFEGKMNWKGQT-YSLDNEKILLRGCVLRNTEWCYGLVIFAGRDTKLMMN 369

Query: 259 STKAPLKRSNVEKVTNVQILVLFGILLVMALVSSVGALFWNGSHG 303
           S K   KR+N+++  N  I+ +F  L+ + L+ +V    W G  G
Sbjct: 370 SGKTKFKRTNIDRYMNKLIIGIFAFLITVCLICTVACGVWEGVIG 504
>06342
          Length = 2428

 Score = 70.5 bits (171), Expect = 4e-12,   Method: Compositional matrix adjust.
 Identities = 120/505 (23%), Positives = 196/505 (38%), Gaps = 25/505 (4%)
 Frame = +2

Query: 368  AMARTSNLNEELGQVKYLFSDKTGTLTCNIMNFKKCSIAGVTYGHFPELAREQSSDDFCR 427
            A+ R+    E LG    + SDKTGTLT N M+  K  I       F ++   Q       
Sbjct: 563  AIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCKLFI-------FSQIDTNQIKTTQFE 721

Query: 428  MTSCTNDSCDFNDPRLLKNIEDQHPTA-PCIQEFLTLLAVCHTVVPEKDGDEIIYQ-ASS 485
            +T  T       D  L +N +    +  P ++E  T+  +C+    + +  +  Y+    
Sbjct: 722  VTGSTYAP----DGELYQNGKKVKASDYPGLEELCTICGMCNDSSVDYNEAKTQYEKVGE 889

Query: 486  PDEAALVKGAKKLGFVFTGRTPYSVIIEAMGQEQTFGILNV------LEFSSDRKRMSVI 539
              E AL   A+KL F  T ++  S+    MG      I ++      LEFS DRK MSV 
Sbjct: 890  ATETALTVLAEKLNFYNTDKS--SLNKREMGTVCNHVIQDMWRKEFTLEFSRDRKSMSVF 1063

Query: 540  ------VRLPSGQLRLYCKGADNVIFERLS---------KDSKYMEETLCHLEYFATEGL 584
                   R+P G  R++ KGA   + +R +           S  ++  +  L      G 
Sbjct: 1064 CVPNKPTRVPGGA-RMFAKGAPEGLLDRCTHVRIGNNKVPMSPAIKNEIMKLTKIYGTGR 1240

Query: 585  RTL-CVAYADLSENEYEEWLKVYQEASIILKDRAQRLEECYEIIEKNLLLLGATAIEDRL 643
             TL C+A A +      E +         L+D  + +E      E N+  +G   + D  
Sbjct: 1241 DTLRCLALATIDNPPRREDMD--------LEDSRKFIE-----YETNMTFVGVVGMLDPP 1381

Query: 644  QAGVPETIATLLKAEIKIWVLTGDKQETAINIGYSCRLVSQNMALILLKEDSLDATRAAI 703
            +  V  +I     A I++ V+TGD + TA  I                            
Sbjct: 1382 REEVMASIKNCRAAGIRVIVITGDNKATAEAI---------------------------- 1477

Query: 704  TQHCTDLGNLLGKENDVALIIDGHTLKYALSFEVRRSFLDLALSCKAVICCRVSPLQKSE 763
               C  +G     EN   L   G         + R + +      +A +  RV P  KS+
Sbjct: 1478 ---CRRIGVFSESENTEGLAYTGREFDELPPEDQRAAVM------RARLFARVEPAHKSK 1630

Query: 764  IVDVVKKRVKAITLAIGDGANDVGMIQTAHVGVGISGNEGMQATNNSDYAIAQFSYLEKL 823
            IV+ ++   + I+   GDG ND   ++ A +G+ + G+    A + S+  +A  ++   +
Sbjct: 1631 IVEYLQAEGE-ISAMTGDGVNDAPALKKAEIGIAM-GSGTAVAKSASEMVLADDNFSTIV 1804

Query: 824  LLV-HGAWSYNRVTKCILYCFYKNV 847
              V  G   YN + + I Y    N+
Sbjct: 1805 AAVEEGRAIYNNMKQFIRYLISSNI 1879
>07699
          Length = 1314

 Score = 57.0 bits (136), Expect = 4e-08,   Method: Compositional matrix adjust.
 Identities = 58/210 (27%), Positives = 90/210 (42%), Gaps = 1/210 (0%)
 Frame = +2

Query: 916  FNTKVFWGHCINALVHSLILFWVPMKALEHDTPVTSGHATDYLFVGNIVYTYVVVTVCLK 975
            FN  VF       ++ S+ LF++P  AL +          D    G +V   +VV V LK
Sbjct: 8    FNLHVFLWSVTEGVLSSIALFFIPYGALIYSVDKDGIDKGDLQSFGTVVAATLVVAVNLK 187

Query: 976  AGLETTAWTKFSHLAVWGSMLIWLVF-FGVYSTIWPTIPIAPDMKGQATMVLSSAYFWLG 1034
              L+ + WT F+H  VWGS++ +  F    YS       I  +  G A  V  +   W  
Sbjct: 188  CALDMSYWTGFNHFVVWGSIIYYFCFQLAFYSE-----AIVYEYVGAAFEVFGNPVTWFT 352

Query: 1035 LFLVPTACLIEDVAWRAAKHTCKKTLLEEVQELETKSRVMGKAMLRDSNGKRMNERDRLI 1094
            + L  T  ++  VA+R  + +   TL +         RV  +  LR S  K    R+  +
Sbjct: 353  MLLTCTLLIMPMVAYRFYQTSVNPTLSD---------RVRLRQRLRKSKSK---GRELHV 496

Query: 1095 KRLSRKTPPTLFRTGSIQQCVSHGYAFSQE 1124
            +R S     T  R+   Q+ +  GYAF+ +
Sbjct: 497  RRQS-----TFRRS---QRSIRSGYAFAHQ 562
>00499
          Length = 4026

 Score = 45.1 bits (105), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 51/220 (23%), Positives = 96/220 (43%), Gaps = 3/220 (1%)
 Frame = +2

Query: 631 LLLLGATAIEDRLQAGVPETIATLLKAEIKIWVLTGDKQETAINIGYSCRLVSQNMALIL 690
           L  +G  A+ D  +A VP+ +     A IK+ ++TGD   TA  I     ++S+    + 
Sbjct: 746 LRFVGLMAMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIARGVGIISEGSKTV- 922

Query: 691 LKEDSLDATRAAITQHCTDLGNLLGKENDVALIIDGHTLKYALSFEVRRSFLDLALSCKA 750
             ED   A+   I     D           A +I G  L+     ++     ++  +   
Sbjct: 923 --EDI--ASERGIPVEEVD------PREAKAAVIHGGDLRDMTPAQID----EILRNHSE 1060

Query: 751 VICCRVSPLQKSEIVDVVKKRVKAITLAIGDGANDVGMIQTAHVGV--GISGNEGMQATN 808
           ++  R SP QK  IV+  +++ + + +  GDG ND   ++ A +GV  GI+G++   +  
Sbjct: 1061IVFARTSPQQKLIIVEGCQRQGQIVAVT-GDGVNDSPALKKADIGVAMGIAGSD--VSKQ 1231

Query: 809 NSDYAIAQFSYLEKLLLV-HGAWSYNRVTKCILYCFYKNV 847
            +D  +   ++   +  V  G   ++ + K I Y    N+
Sbjct: 1232AADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNI 1351
>14321
          Length = 568

 Score = 43.1 bits (100), Expect = 6e-04,   Method: Composition-based stats.
 Identities = 42/146 (28%), Positives = 65/146 (44%), Gaps = 11/146 (7%)
 Frame = +2

Query: 667 DKQETAINIGYSCRLVSQNMALILLKEDSLDATRAAITQHCTDLGNLLGKENDVA----- 721
           D   TA ++    R+  ++  LIL   + LD+       H   + + + +  D A     
Sbjct: 2   DNPLTACHVAKELRMTRKDKTLILTPPNRLDSD-----WHWQSIDDSVTQSLDPASLRKS 166

Query: 722 ------LIIDGHTLKYALSFEVRRSFLDLALSCKAVICCRVSPLQKSEIVDVVKKRVKAI 775
                 L + G +L +  S   +   L L L    V   RV+P QK  I+ V+K +   +
Sbjct: 167 IIPKYDLCLTGESLTFLQSDHPK--LLRLLLPNTRVFA-RVAPKQKELIITVLKAQ-GFV 334

Query: 776 TLAIGDGANDVGMIQTAHVGVGISGN 801
           TL  GDG NDVG ++ A VGV +  N
Sbjct: 335 TLMCGDGTNDVGALKHADVGVALLAN 412
>28890
          Length = 552

 Score = 37.0 bits (84), Expect = 0.044,   Method: Compositional matrix adjust.
 Identities = 24/91 (26%), Positives = 48/91 (52%), Gaps = 3/91 (3%)
 Frame = -3

Query: 115 IVLRNGMWHTIMWKEVAVGDIVKVLNGQYLPADMVLFSSSEPQGMCYVETANLDGETNLK 174
           +V+R     ++  +E+ VGDIV+   G  +PAD+ + S+   +    V+ ++L GE+  +
Sbjct: 466 VVVRGDQKLSVKAEELVVGDIVECKFGDRVPADLRVISAHGFK----VDNSSLTGESEPQ 299

Query: 175 IRQG-LSHTTDMQTRDVLMKLSGRIE--CEG 202
            R    +H   ++TR++    +  +E  C G
Sbjct: 298 SRSAEFTHENPLETRNICFFSTNAVEGTCRG 206
>21541
          Length = 445

 Score = 36.2 bits (82), Expect = 0.078,   Method: Composition-based stats.
 Identities = 17/40 (42%), Positives = 25/40 (62%)
 Frame = +3

Query: 116 VLRNGMWHTIMWKEVAVGDIVKVLNGQYLPADMVLFSSSE 155
           V+RNG  H I   E+ VG+I ++  G  LPAD V+  S++
Sbjct: 132 VIRNGELHQIPVGEILVGEICQIKYGDLLPADGVIIQSND 251
>03521
          Length = 439

 Score = 35.0 bits (79), Expect = 0.19,   Method: Composition-based stats.
 Identities = 22/65 (33%), Positives = 31/65 (47%), Gaps = 2/65 (3%)
 Frame = -3

Query: 789 IQTAHVGVGISGNEGMQATNNSDYAIAQFSYLEKLLLVHGA--WSYNRVTKCILYCFYKN 846
           +  +  G G+ G     A N S   I QF  L++ +L       SYNR+ + ILYCF   
Sbjct: 317 VNNSACGGGVGGMSSDTAPNFSQLFIFQFPCLKEYVLPGPPQHLSYNRIIRSILYCFVNV 138

Query: 847 VVLYI 851
            V Y+
Sbjct: 137 CV*YV 123
>04985
          Length = 1671

 Score = 33.5 bits (75), Expect = 0.45,   Method: Compositional matrix adjust.
 Identities = 16/58 (27%), Positives = 31/58 (53%)
 Frame = -1

Query: 749  KAVICCRVSPLQKSEIVDVVKKRVKAITLAIGDGANDVGMIQTAHVGVGISGNEGMQA 806
            +  +  R++P QK  +++ ++     + +  GDGAND   ++ AH G+ +S  E   A
Sbjct: 1617 QGTVFARMAPDQKCALIENLQSYDYIVGMC-GDGANDCEALKAAHAGISLSEAEASVA 1447
>36548
          Length = 115

 Score = 32.7 bits (73), Expect = 0.79,   Method: Compositional matrix adjust.
 Identities = 14/25 (56%), Positives = 17/25 (68%)
 Frame = +3

Query: 579 FATEGLRTLCVAYADLSENEYEEWL 603
             +EGLRTLC+A   LS+ EY  WL
Sbjct: 6   LCSEGLRTLCMARRVLSKEEYTTWL 80
>00109
          Length = 945

 Score = 30.0 bits (66), Expect = 6.3,   Method: Compositional matrix adjust.
 Identities = 23/87 (26%), Positives = 41/87 (47%), Gaps = 2/87 (2%)
 Frame = -1

Query: 330 YN-NLIPI-SLLVTLEVVKYTQALFINWDMDMYYIENDTPAMARTSNLNEELGQVKYLFS 387
           YN NL P+  L+V+L  + + +  +I           DT +M R S L+ +L  + Y+  
Sbjct: 456 YN*NLAPLLYLIVSLPTILFXEGFYIT--------SMDTKSMGRXSKLS*QLT*LVYMIM 301

Query: 388 DKTGTLTCNIMNFKKCSIAGVTYGHFP 414
           +   T  CN+   K+C  + ++    P
Sbjct: 300 NSAVTH*CNM*QRKQCKSSAISLHTXP 220
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|111074522|ref|NP_075604.2| protocadherin 15 isoform
CD1-1 [Mus musculus]
         (1943 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

01558                                                                 139   1e-32
36752                                                                  86   7e-29
17709                                                                  90   1e-17
29507                                                                  88   3e-17
08409                                                                  88   3e-17
19661                                                                  83   9e-16
25641                                                                  77   5e-14
12703                                                                  76   1e-13
18971                                                                  59   2e-13
29160                                                                  75   3e-13
19334                                                                  71   5e-13
35151                                                                  74   7e-13
14946                                                                  73   1e-12
14391                                                                  72   2e-12
37991                                                                  64   5e-10
34098                                                                  64   6e-10
18709                                                                  61   4e-09
38442                                                                  59   2e-08
12240                                                                  58   5e-08
27585                                                                  55   3e-07
24587                                                                  52   3e-06
18019                                                                  51   4e-06
14137                                                                  50   6e-06
13573                                                                  50   8e-06
08534                                                                  49   2e-05
38001                                                                  48   3e-05
15121                                                                  48   5e-05
33294                                                                  47   5e-05
29630                                                                  47   1e-04
29492                                                                  44   5e-04
37203                                                                  42   0.002
26675                                                                  41   0.005
18725                                                                  37   0.055
07525                                                                  37   0.059
33084                                                                  33   1.5  
35745                                                                  32   1.8  
28153                                                                  32   2.4  
17610                                                                  30   9.8  
>01558
          Length = 2767

 Score =  139 bits (349), Expect = 1e-32,   Method: Compositional matrix adjust.
 Identities = 205/831 (24%), Positives = 348/831 (41%), Gaps = 58/831 (6%)
 Frame = +2

Query: 342  FFHMHPRTAELTLLEPV--NRDFHQKFDLVIKAEQDNGHP-LPAFASLHIEILDENNQSP 398
            +F ++  +  +++  P+  N D    + L++ A +D G+P +    S+ I +L  N  SP
Sbjct: 206  YFSLNENSGAISVRRPLTGNSDVFASYTLLVTA-RDTGNPDIVVSESVQINVL-RNLNSP 379

Query: 399  YFTMPSYQGYILESAPVGATISESLNLTTPLRIVALDKDIED-----TKDPELHLFLNDY 453
             F   +Y   + +   VG+++         +++ A D DI D     T + E     N++
Sbjct: 380  VFGQQTYTQSVYDYESVGSSV---------VQVDATDSDITDPENQLTFEIESGATANEF 532

Query: 454  TSVFTVTP-TGITRY---LTLLQPVDREEQQTYTFLITAFDGVQESEPVVVNIRV-MDAN 508
               F + P TGI R    LTL  P        Y F + A D    S     ++ V +  N
Sbjct: 533  ---FNIDPFTGIIRISKELTLSTP------SAYNFRVIARDLGALSRAATASVVVTILRN 685

Query: 509  DNTPTFPEI-SYDVYVYTDMSPGDSVIQLTAVDADEGS--NGEISYEIL--VGGKGDFVI 563
               P F    S DV V   +S  D+++ L AVD+D  +  NG ++Y I+  +  +  F I
Sbjct: 686  TGRPAFVNSPSADVIVSEAISVLDTIVTLKAVDSDPDTTPNGRVTYSIVSPIEARAFFQI 865

Query: 564  NKTTGLVSIAPGVELIVGQTYALTVQASDNAPPAERRHSICTVYIEVLPPNNQSPPRFPQ 623
            +   G ++    +       Y LTV+ASD   P +      T+ I       +  P F Q
Sbjct: 866  DPVLGNITARVSLTTAPVDVYRLTVRASDQGTPTQSSEVTVTIRIR-----REGNPSFAQ 1030

Query: 624  LMYSLEVSEAMRIGAILLNLQATDREGDPITYAIE-NGDPQRVFNLSETTGILSLGKALD 682
              Y + + E   +   ++ L ATD     + Y I  +G    +F L   TG+++L ++L 
Sbjct: 1031 SEYVVTLPEDTPLSTSIIKLTATDPLARQLQYEITGDGMASTLFRLDVDTGLITLAQSLR 1210

Query: 683  RESTDRYILIVTASDGRPDGTSXXXXXXXXXXXXXXXPVFDPYLPRNLSVVEEEANAF-- 740
             ++ + +++ + A     +                  P F   L  +++V   E  A   
Sbjct: 1211 SDTANSFVIRLVAFRVNDNSVXATTIVRVLVTRNANDPAF---LHGDIAVTLSEDQALGV 1381

Query: 741  -VGQVRATDPDAGINGQVHYSLGN-------FNNLFRIT-SNGSIYTAVKLNREARD--H 789
               +V ATD D+G NG + Y++          N  F I  ++GS+  + +L+ +      
Sbjct: 1382 AFLKVNATDADSGDNGAITYNIDGDKSEPTYVNQYFYINPTSGSLAVSSRLSDDTNMPVL 1561

Query: 790  YELVVVATDGAVHPRHSTLTLYIKVLDIDDNSPVFTNSTYTVVVEENLPAGTSFLQIEAK 849
            Y L VVA D  V  R S+       +  + NSPVF+ S Y V V+E +    S +++ A 
Sbjct: 1562 YVLYVVAIDNGVV-RRSSFIRVRVTVVRNRNSPVFSQSLYNVTVDETIGVTQSLIRVTAS 1738

Query: 850  DVDLGANVSYRIRSPEVKHL-FALHPFTGELSLLRSLDYEAFPDQEASITFLVEAFD--I 906
            D D G  ++Y + S     L F +   +G + +  SL      D   + T  +EA D  +
Sbjct: 1739 DAD-GDRITYSMLSSIPASLYFDVDSTSGIVRIRNSL----LQDSTVTYTMDIEALDAPV 1903

Query: 907  YGTMP-PGIATVTVIVKDMNDYPPVFSKRIYKGMVAPDAVKGTPITTVYAEDADPPGMPA 965
             G  P   +A V V V+  N   P+F + +Y   V+      + I TV A DAD    P+
Sbjct: 1904 QGASPRNALAKVIVNVR-RNPNTPIFDQSVYNVTVSEYIPVRSVIQTVLARDADAASTPS 2080

Query: 966  SRVRYRVDDVQFPYP--------ASIFDVEEDSGRVVTRVNLNEEPT-TIFKLVVVAFDD 1016
             R+ Y +  V +P P        A  F     +G ++    L++      F +V+ A D 
Sbjct: 2081 GRLVYSIVSVSYPDPQFNVAPQQADFFIASPTTGDIILAQQLSQARVPDRFDIVIKAADS 2260

Query: 1017 GEPVMSSSATVRILVLHPGEIPRFTQEEYRPPPVSELAARGTVVGVISAAAINQSIVYSI 1076
              P  SS   + + ++     P FT+  Y    + +  A G  +  ++A   +    Y+ 
Sbjct: 2261 AIPPKSSQTLLSVNIIRNIHRPEFTEIRY-GAAIEDTWAVGRTLFTVTAVDDDDKEQYNQ 2437

Query: 1077 VAGN-------------EEDKFGINNVTGVIYVNSPLDYETRTSYVLRVQA 1114
               N              E  FG+  + GV+YV + L  +   SY   + A
Sbjct: 2438 NTNNAFFDYMIDENYPLAETYFGV-TIDGVVYVRNNLLLDNSASYFFYIIA 2587

 Score =  111 bits (277), Expect = 3e-24,   Method: Compositional matrix adjust.
 Identities = 125/468 (26%), Positives = 201/468 (42%), Gaps = 14/468 (2%)
 Frame = +2

Query: 735  EEANAFVGQVRATDPDAGINGQVHYSLGNFN---NLFRITSNG---SIYTAVKLNREARD 788
            +  N+ V  V+A DPD  + GQ+ Y L  F      F +  N    S+   +  N +   
Sbjct: 107  QAVNSTVISVQAFDPD--LRGQIQYRLEGFQPGITYFSLNENSGAISVRRPLTGNSDVFA 280

Query: 789  HYELVVVATDGAVHPRHSTLTLYIKVLDIDDNSPVFTNSTYTVVVEENLPAGTSFLQIEA 848
             Y L+V A D        + ++ I VL  + NSPVF   TYT  V +    G+S +Q++A
Sbjct: 281  SYTLLVTARDTGNPDIVVSESVQINVLR-NLNSPVFGQQTYTQSVYDYESVGSSVVQVDA 457

Query: 849  KDVDLG---ANVSYRIRS-PEVKHLFALHPFTGELSLLRSLDYEAFPDQEASITFLVEAF 904
             D D+      +++ I S       F + PFTG + + + L         ++  F V A 
Sbjct: 458  TDSDITDPENQLTFEIESGATANEFFNIDPFTGIIRISKELTLST----PSAYNFRVIAR 625

Query: 905  DIYGTMPPGIATVTVIVKDMNDYPPVFSKRIYKGMVAPDAVKGT-PITTVYAEDADPPGM 963
            D+        A+V V +   N   P F       ++  +A+     I T+ A D+DP   
Sbjct: 626  DLGALSRAATASVVVTIL-RNTGRPAFVNSPSADVIVSEAISVLDTIVTLKAVDSDPDTT 802

Query: 964  PASRVRYRVDDVQFPYPA-SIFDVEEDSGRVVTRVNLNEEPTTIFKLVVVAFDDGEPVMS 1022
            P  RV Y +     P  A + F ++   G +  RV+L   P  +++L V A D G P  S
Sbjct: 803  PNGRVTYSIVS---PIEARAFFQIDPVLGNITARVSLTTAPVDVYRLTVRASDQGTPTQS 973

Query: 1023 SSATVRILVLHPGEIPRFTQEEYRPPPVSELAARGTVVGVISAAAINQSIVYSIVA-GNE 1081
            S  TV I +   G  P F Q EY      +     +++ + +   + + + Y I   G  
Sbjct: 974  SEVTVTIRIRREGN-PSFAQSEYVVTLPEDTPLSTSIIKLTATDPLARQLQYEITGDGMA 1150

Query: 1082 EDKFGINNVTGVIYVNSPLDYETRTSYVLRVQADSLEVVLANLRVPSKSNTAKVYIEIQ- 1140
               F ++  TG+I +   L  +T  S+V+R+ A          RV   S  A   + +  
Sbjct: 1151 STLFRLDVDTGLITLAQSLRSDTANSFVIRLVA---------FRVNDNSVXATTIVRVLV 1303

Query: 1141 DENDHPPVFQKKFYIGGVSEDARMFASVLRVKATDRDTGNYSAMAYRL 1188
              N + P F        +SED  +  + L+V ATD D+G+  A+ Y +
Sbjct: 1304 TRNANDPAFLHGDIAVTLSEDQALGVAFLKVNATDADSGDNGAITYNI 1447

 Score =  104 bits (259), Expect = 4e-22,   Method: Compositional matrix adjust.
 Identities = 188/755 (24%), Positives = 319/755 (42%), Gaps = 35/755 (4%)
 Frame = +2

Query: 133  VIYHEVRIVVRDRNDNSPTFKHESYYATVNELTPVGTTIFTGFSGDNGATDIDDGPNGQI 192
            V+   V+I V  RN NSP F  ++Y  +V +   VG+++    + D+  TD    P  Q+
Sbjct: 329  VVSESVQINVL-RNLNSPVFGQQTYTQSVYDYESVGSSVVQVDATDSDITD----PENQL 493

Query: 193  EYVIQYNPEDPTSNDTFEIPLMLTGNVVLRKRLNYEDKTRYYVIIQANDRAQNLNERRXX 252
             + I+      T+N+ F I    TG + + K L     + Y   + A D           
Sbjct: 494  TFEIE---SGATANEFFNID-PFTGIIRISKELTLSTPSAYNFRVIARDLG--------- 634

Query: 253  XXXXXXXXXXXXXXXPMFLPCVLVPNTRDCRPLTYQAAIPELRTPEELNPILVTPPIQAI 312
                              +   ++ NT   RP    +   ++   E ++ +     ++A+
Sbjct: 635  ---------ALSRAATASVVVTILRNT--GRPAFVNSPSADVIVSEAISVLDTIVTLKAV 781

Query: 313  DQDRNIQPPSDRPGILYSILVGTPEDYPRFFHMHPRTAELTLLEPVNRDFHQKFDLVIKA 372
            D D +  P      + YSI+  +P +   FF + P    +T    +       + L ++A
Sbjct: 782  DSDPDTTP---NGRVTYSIV--SPIEARAFFQIDPVLGNITARVSLTTAPVDVYRLTVRA 946

Query: 373  EQDNGHPLPAF-ASLHIEILDENNQSPYFTMPSYQGYILESAPVGATISESLNLTTPLRI 431
              D G P  +   ++ I I  E N  P F    Y   + E  P+  +I + L  T PL  
Sbjct: 947  S-DQGTPTQSSEVTVTIRIRREGN--PSFAQSEYVVTLPEDTPLSTSIIK-LTATDPL-- 1108

Query: 432  VALDKDIEDTKDPELH-LFLNDYTSVFTVTPTGITRYLTLLQPVDREEQQTYTFLITAFD 490
             A     E T D     LF  D         TG+   +TL Q +  +   ++   + AF 
Sbjct: 1109 -ARQLQYEITGDGMASTLFRLD-------VDTGL---ITLAQSLRSDTANSFVIRLVAFR 1255

Query: 491  GVQESEPVVVNIRVM-DANDNTPTFPEISYDVYVYTDMSPGDSVIQLTAVDADEGSNGEI 549
                S      +RV+   N N P F      V +  D + G + +++ A DAD G NG I
Sbjct: 1256 VNDNSVXATTIVRVLVTRNANDPAFLHGDIAVTLSEDQALGVAFLKVNATDADSGDNGAI 1435

Query: 550  SYEILVGGKGD-------FVINKTTGLVSIAPGV--ELIVGQTYALTVQASDNAPPAERR 600
            +Y I  G K +       F IN T+G ++++  +  +  +   Y L V A DN     RR
Sbjct: 1436 TYNID-GDKSEPTYVNQYFYINPTSGSLAVSSRLSDDTNMPVLYVLYVVAIDNG--VVRR 1606

Query: 601  HSICTVYIEVLPPNNQSPPRFPQLMYSLEVSEAMRIGAILLNLQATDREGDPITYAIENG 660
             S   + + V    N++ P F Q +Y++ V E + +   L+ + A+D +GD ITY++ + 
Sbjct: 1607 SSF--IRVRVTVVRNRNSPVFSQSLYNVTVDETIGVTQSLIRVTASDADGDRITYSMLSS 1780

Query: 661  DPQRV-FNLSETTGILSLGKALDRESTDRYILIVTASDGRPDGTS---XXXXXXXXXXXX 716
             P  + F++  T+GI+ +  +L ++ST  Y + + A D    G S               
Sbjct: 1781 IPASLYFDVDSTSGIVRIRNSLLQDSTVTYTMDIEALDAPVQGASPRNALAKVIVNVRRN 1960

Query: 717  XXXPVFDPYLPRNLSVVEE-EANAFVGQVRATDPDAGI--NGQVHYSLGN-------FNN 766
               P+FD  +  N++V E     + +  V A D DA    +G++ YS+ +       FN 
Sbjct: 1961 PNTPIFDQSV-YNVTVSEYIPVRSVIQTVLARDADAASTPSGRLVYSIVSVSYPDPQFNV 2137

Query: 767  L-----FRITS--NGSIYTAVKLNREAR--DHYELVVVATDGAVHPRHSTLTLYIKVLDI 817
                  F I S   G I  A +L+ +AR  D +++V+ A D A+ P+ S   L + ++  
Sbjct: 2138 APQQADFFIASPTTGDIILAQQLS-QARVPDRFDIVIKAADSAIPPKSSQTLLSVNIIR- 2311

Query: 818  DDNSPVFTNSTYTVVVEENLPAGTSFLQIEAKDVD 852
            + + P FT   Y   +E+    G +   + A D D
Sbjct: 2312 NIHRPEFTEIRYGAAIEDTWAVGRTLFTVTAVDDD 2416

 Score = 96.3 bits (238), Expect = 1e-19,   Method: Compositional matrix adjust.
 Identities = 178/718 (24%), Positives = 301/718 (41%), Gaps = 28/718 (3%)
 Frame = +2

Query: 491  GVQESEPVVVNIRVMDANDNTPTFPEISYDVYVYTDMSPGDSVIQLTAVDADEGSNGEIS 550
             V+ S    V I V+  +   P F    Y V V    +   +VI + A D D    G+I 
Sbjct: 2    SVRRSAQATVTINVL-RDSGPPVFQNTPYVVPVPLTQAVNSTVISVQAFDPDL--RGQIQ 172

Query: 551  YEI--LVGGKGDFVINKTTGLVSIAPGV--ELIVGQTYALTVQASDNAPPAERRHSICTV 606
            Y +     G   F +N+ +G +S+   +     V  +Y L V A D   P      + + 
Sbjct: 173  YRLEGFQPGITYFSLNENSGAISVRRPLTGNSDVFASYTLLVTARDTGNP----DIVVSE 340

Query: 607  YIEVLPPNNQSPPRFPQLMYSLEVSEAMRIGAILLNLQATDRE-GDP---ITYAIENG-D 661
             +++    N + P F Q  Y+  V +   +G+ ++ + ATD +  DP   +T+ IE+G  
Sbjct: 341  SVQINVLRNLNSPVFGQQTYTQSVYDYESVGSSVVQVDATDSDITDPENQLTFEIESGAT 520

Query: 662  PQRVFNLSETTGILSLGKALDRESTDRYILIVTASDGRPDGTSXXXXXXXXXXXXXXXPV 721
                FN+   TGI+ + K L   +   Y   V A D      +               P 
Sbjct: 521  ANEFFNIDPFTGIIRISKELTLSTPSAYNFRVIARDLGALSRAATASVVVTILRNTGRPA 700

Query: 722  F------DPYLPRNLSVVEEEANAFVGQVRA--TDPDAGINGQVHYSLGN---FNNLFRI 770
            F      D  +   +SV++      +  ++A  +DPD   NG+V YS+ +       F+I
Sbjct: 701  FVNSPSADVIVSEAISVLDT-----IVTLKAVDSDPDTTPNGRVTYSIVSPIEARAFFQI 865

Query: 771  TSN-GSIYTAVKLNREARDHYELVVVATDGAVHPRHSTLTLYIKVLDIDDNSPVFTNSTY 829
                G+I   V L     D Y L V A+D     + S +T+ I++    + +P F  S Y
Sbjct: 866  DPVLGNITARVSLTTAPVDVYRLTVRASDQGTPTQSSEVTVTIRIRR--EGNPSFAQSEY 1039

Query: 830  TVVVEENLPAGTSFLQIEAKDVDLGANVSYRIRSPEVKH-LFALHPFTGELSLLRSLDYE 888
             V + E+ P  TS +++ A D  L   + Y I    +   LF L   TG ++L +SL   
Sbjct: 1040 VVTLPEDTPLSTSIIKLTATD-PLARQLQYEITGDGMASTLFRLDVDTGLITLAQSLR-- 1210

Query: 889  AFPDQEASITFLVEAFDIYGTMPPGIATVTVIV-KDMNDYPPVFSKRIYKGMVAPDAVKG 947
               D   S    + AF +          V V+V ++ ND  P F        ++ D   G
Sbjct: 1211 --SDTANSFVIRLVAFRVNDNSVXATTIVRVLVTRNAND--PAFLHGDIAVTLSEDQALG 1378

Query: 948  TPITTVYAEDADPPGMPASRVRYRVD-DVQFP-YPASIFDVEEDSGRVVTRVNLNEEPT- 1004
                 V A DAD     A  + Y +D D   P Y    F +   SG +     L+++   
Sbjct: 1379 VAFLKVNATDADSGDNGA--ITYNIDGDKSEPTYVNQYFYINPTSGSLAVSSRLSDDTNM 1552

Query: 1005 -TIFKLVVVAFDDGEPVMSSSATVRILVLHPGEIPRFTQEEYRPPPVSELAARGTVVGVI 1063
              ++ L VVA D+G    SS   VR+ V+     P F+Q  Y       +    +++ V 
Sbjct: 1553 PVLYVLYVVAIDNGVVRRSSFIRVRVTVVRNRNSPVFSQSLYNVTVDETIGVTQSLIRVT 1732

Query: 1064 SAAAINQSIVYSIVAGNEED-KFGINNVTGVIYVNSPLDYETRTSYVLRVQADSLEVVLA 1122
            ++ A    I YS+++       F +++ +G++ + + L  ++  +Y + ++A    V  A
Sbjct: 1733 ASDADGDRITYSMLSSIPASLYFDVDSTSGIVRIRNSLLQDSTVTYTMDIEALDAPVQGA 1912

Query: 1123 NLRVPSKSNTAKVYIEIQDENDHPPVFQKKFYIGGVSEDARMFASVLRVKATDRDTGN 1180
            + R    +  AKV + ++  N + P+F +  Y   VSE   + + +  V A D D  +
Sbjct: 1913 SPR----NALAKVIVNVR-RNPNTPIFDQSVYNVTVSEYIPVRSVIQTVLARDADAAS 2071

 Score = 62.4 bits (150), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 109/443 (24%), Positives = 193/443 (43%), Gaps = 17/443 (3%)
 Frame = +2

Query: 804  RHSTLTLYIKVLDIDDNSPVFTNSTYTVVVEENLPAGTSFLQIEAKDVDLGANVSYRIRS 863
            R +  T+ I VL  D   PVF N+ Y V V       ++ + ++A D DL   + YR+  
Sbjct: 11   RSAQATVTINVLR-DSGPPVFQNTPYVVPVPLTQAVNSTVISVQAFDPDLRGQIQYRLEG 187

Query: 864  --PEVKHLFALHPFTGELSLLRSLDYEAFPDQEASITFLVEAFDIYGTMPPGIA---TVT 918
              P + + F+L+  +G +S+ R L   +  D  AS T LV A D   T  P I    +V 
Sbjct: 188  FQPGITY-FSLNENSGAISVRRPLTGNS--DVFASYTLLVTARD---TGNPDIVVSESVQ 349

Query: 919  V-IVKDMNDYPPVFSKRIYKGMVAPDAVKGTPITTVYAEDADPPGMPASRVRYRVDDVQF 977
            + +++++N   PVF ++ Y   V      G+ +  V A D+D    P +++ + ++    
Sbjct: 350  INVLRNLNS--PVFGQQTYTQSVYDYESVGSSVVQVDATDSDITD-PENQLTFEIE--SG 514

Query: 978  PYPASIFDVEEDSGRVVTRVNLNEEPTTIFKLVVVAFDDGEPVMSSSATVRILVLHPGEI 1037
                  F+++  +G +     L     + +   V+A D G    +++A+V + +L     
Sbjct: 515  ATANEFFNIDPFTGIIRISKELTLSTPSAYNFRVIARDLGALSRAATASVVVTILRNTGR 694

Query: 1038 PRFTQEEYRPPPVSELAARGTVVGVISAAAI--------NQSIVYSIVAGNEEDK-FGIN 1088
            P F         VSE  A   +  +++  A+        N  + YSIV+  E    F I+
Sbjct: 695  PAFVNSPSADVIVSE--AISVLDTIVTLKAVDSDPDTTPNGRVTYSIVSPIEARAFFQID 868

Query: 1089 NVTGVIYVNSPLDYETRTSYVLRVQADSLEVVLANLRVPSKSNTAKVYIEIQDENDHPPV 1148
             V G I     L       Y L V+A       ++   P++S+   V I I+ E +  P 
Sbjct: 869  PVLGNITARVSLTTAPVDVYRLTVRA-------SDQGTPTQSSEVTVTIRIRREGN--PS 1021

Query: 1149 FQKKFYIGGVSEDARMFASVLRVKATDRDTGNYSAMAYRLIIPPIKEGKEG--FVVETYT 1206
            F +  Y+  + ED  +  S++++ ATD        +A +L      +G     F ++  T
Sbjct: 1022 FAQSEYVVTLPEDTPLSTSIIKLTATD-------PLARQLQYEITGDGMASTLFRLDVDT 1180

Query: 1207 GLIKTAMLFHNMRRSYFKFQVIA 1229
            GLI  A    +   + F  +++A
Sbjct: 1181 GLITLAQSLRSDTANSFVIRLVA 1249

 Score = 37.4 bits (85), Expect = 0.065,   Method: Compositional matrix adjust.
 Identities = 60/232 (25%), Positives = 98/232 (42%), Gaps = 5/232 (2%)
 Frame = +2

Query: 1022 SSSATVRILVLHPGEIPRFTQEEYRPPPVSELAARGTVVGVISAAAINQSIVYSIVAGNE 1081
            S+ ATV I VL     P F    Y  P     A   TV+ V +     +  +   + G +
Sbjct: 14   SAQATVTINVLRDSGPPVFQNTPYVVPVPLTQAVNSTVISVQAFDPDLRGQIQYRLEGFQ 193

Query: 1082 ED--KFGINNVTGVIYVNSPL--DYETRTSYVLRVQADSLEVVLANLRVPSKSNTAKVYI 1137
                 F +N  +G I V  PL  + +   SY L V A        +   P    +  V I
Sbjct: 194  PGITYFSLNENSGAISVRRPLTGNSDVFASYTLLVTA-------RDTGNPDIVVSESVQI 352

Query: 1138 EIQDENDHPPVFQKKFYIGGVSEDARMFASVLRVKATDRD-TGNYSAMAYRLIIPPIKEG 1196
             +   N + PVF ++ Y   V +   + +SV++V ATD D T   + + +   I      
Sbjct: 353  NVL-RNLNSPVFGQQTYTQSVYDYESVGSSVVQVDATDSDITDPENQLTFE--IESGATA 523

Query: 1197 KEGFVVETYTGLIKTAMLFHNMRRSYFKFQVIATDDYGKGLSGKADVLVSVV 1248
             E F ++ +TG+I+ +        S + F+VIA D      +  A V+V+++
Sbjct: 524  NEFFNIDPFTGIIRISKELTLSTPSAYNFRVIARDLGALSRAATASVVVTIL 679

 Score = 31.2 bits (69), Expect = 4.4,   Method: Compositional matrix adjust.
 Identities = 21/91 (23%), Positives = 41/91 (45%), Gaps = 7/91 (7%)
 Frame = +2

Query: 89  WVLLDPVKQMLFL-------NSTGRVLDRDPPMNIHSIVVQVQCVNKKVGTVIYHEVRIV 141
           + ++ P++   F        N T RV     P++++ + V+         +    EV + 
Sbjct: 821 YSIVSPIEARAFFQIDPVLGNITARVSLTTAPVDVYRLTVRASDQGTPTQS---SEVTVT 991

Query: 142 VRDRNDNSPTFKHESYYATVNELTPVGTTIF 172
           +R R + +P+F    Y  T+ E TP+ T+I 
Sbjct: 992 IRIRREGNPSFAQSEYVVTLPEDTPLSTSII 1084
>36752
          Length = 1243

 Score = 80.1 bits (196), Expect(2) = 7e-29,   Method: Compositional matrix adjust.
 Identities = 78/263 (29%), Positives = 121/263 (46%), Gaps = 5/263 (1%)
 Frame = +3

Query: 307 PPIQAIDQDRNIQPPSDRPGILYSILVGTPEDYPRFFHMHPRTAELTLLEPVNRDFHQKF 366
           P IQA D+D   +  +    I Y+ L G   D+   F +   +  L     ++R+  Q++
Sbjct: 3   PTIQASDRD---EASTQNARITYT-LDGQGADH---FMLEKDSGILRTAAALDRETQQRY 161

Query: 367 DLVIKAEQDNGHPLPAFASLHIEILDENNQSPYFTMPSYQGYILESAPVGATISESLNLT 426
            L + A   +G  L     + I + D N+  P FT         +S     T+ E   + 
Sbjct: 162 HLEVTAT--DGGGLSCVTEVQIFLRDVNDXPPEFT---------DSLRDTLTVQEDARVN 308

Query: 427 TPL-RIVALDKDIEDTKDPELHLFLNDYTSVFTVTP-TGITRYLTLLQPVDREEQQTYTF 484
           T L R+  +DKD    ++    L   +  SVF++ P +GI   L+L+  +DREE   Y  
Sbjct: 309 TLLTRVTTVDKDTGINRNTRYELMQRE-PSVFSIEPKSGI---LSLVGSLDREEHPQYDV 476

Query: 485 LITAFDGVQE--SEPVVVNIRVMDANDNTPTFPEISYDVYVYTDMSPGDSVIQLTAVDAD 542
            I A++ +    S   V+ + V+D NDN PTF   SY   V  D   G  V ++ A   D
Sbjct: 477 TIVAYNEISPALSATTVLKVVVLDVNDNPPTFERTSYYAAVAEDAGVGTVVGRVRATSLD 656

Query: 543 EGSNGEISYEILVGG-KGDFVIN 564
            G+N  I+Y I  G  +G FVI+
Sbjct: 657 IGANAAITYSIAAGNQQGKFVID 725

 Score = 67.8 bits (164), Expect(2) = 7e-29,   Method: Compositional matrix adjust.
 Identities = 48/140 (34%), Positives = 76/140 (54%), Gaps = 7/140 (5%)
 Frame = +1

Query: 568 GLVSIAPGVELIVGQTYALTVQASDNAPPAERRHSICTVYIEVLPPNNQSPPRFPQLMYS 627
           G + ++  ++  V + Y LT+ A D+  P     +I ++ I  +   N +PPRF Q  Y+
Sbjct: 736 GEIKVSEPLDHEVSREYFLTILARDHGSPPLSNTAIISINITDI---NDNPPRFSQDTYA 906

Query: 628 LEVSEAMRIGAILLNLQATDREG---DPITYAIENGDPQRVFNLSETT---GILSLGKAL 681
             VSE + +G  +  + ATD +      ITY+I +G+P R   LS+     GI+ + K L
Sbjct: 907 TTVSEVVLVGTEVFKVMATDADSYANSVITYSIIDGNPVR--QLSDWVLRDGIIQVAKHL 1080

Query: 682 DRESTDRYILIVTASD-GRP 700
           DRES +RY L + A D G+P
Sbjct: 1081DRESVERYALTIQARDSGQP 1140

 Score = 85.1 bits (209), Expect(2) = 1e-26,   Method: Compositional matrix adjust.
 Identities = 72/228 (31%), Positives = 112/228 (49%), Gaps = 12/228 (5%)
 Frame = +3

Query: 744 VRATDPDAGI--NGQVHYSL-GNFNNLFRITSN-GSIYTAVKLNREARDHYELVVVATDG 799
           ++A+D D     N ++ Y+L G   + F +  + G + TA  L+RE +  Y L V ATDG
Sbjct: 9   IQASDRDEASTQNARITYTLDGQGADHFMLEKDSGILRTAAALDRETQQRYHLEVTATDG 188

Query: 800 AVHPRHSTLTLYIKVLDIDDNSPVFTNSTY-TVVVEENLPAGTSFLQIEAKDVDLGANVS 858
                 + + ++++  D++D  P FT+S   T+ V+E+    T   ++   D D G N +
Sbjct: 189 GGLSCVTEVQIFLR--DVNDXPPEFTDSLRDTLTVQEDARVNTLLTRVTTVDKDTGINRN 362

Query: 859 YRI----RSPEVKHLFALHPFTGELSLLRSLDYEAFPDQEASITFLVEAFDIYGTMPPGI 914
            R     R P V   F++ P +G LSL+ SLD E  P  + +I         Y  + P +
Sbjct: 363 TRYELMQREPSV---FSIEPKSGILSLVGSLDREEHPQYDVTIV-------AYNEISPAL 512

Query: 915 ATVTV---IVKDMNDYPPVFSKRIYKGMVAPDAVKGTPITTVYAEDAD 959
           +  TV   +V D+ND PP F +  Y   VA DA  GT +  V A   D
Sbjct: 513 SATTVLKVVVLDVNDNPPTFERTSYYAAVAEDAGVGTVVGRVRATSLD 656

 Score = 55.5 bits (132), Expect(2) = 1e-26,   Method: Compositional matrix adjust.
 Identities = 51/158 (32%), Positives = 80/158 (50%), Gaps = 7/158 (4%)
 Frame = +1

Query: 999  LNEEPTTIFKLVVVAFDDGEPVMSSSATVRILVLHPGEI-PRFTQEEYRPPPVSELAARG 1057
            L+ E +  + L ++A D G P +S++A + I +    +  PRF+Q+ Y    VSE+   G
Sbjct: 760  LDHEVSREYFLTILARDHGSPPLSNTAIISINITDINDNPPRFSQDTY-ATTVSEVVLVG 936

Query: 1058 TVVGVISA----AAINQSIVYSIVAGNEEDKFGINNV-TGVIYVNSPLDYETRTSYVLRV 1112
            T V  + A    +  N  I YSI+ GN   +     +  G+I V   LD E+   Y L +
Sbjct: 937  TEVFKVMATDADSYANSVITYSIIDGNPVRQLSDWVLRDGIIQVAKHLDRESVERYALTI 1116

Query: 1113 QA-DSLEVVLANLRVPSKSNTAKVYIEIQDENDHPPVF 1149
            QA DS +        P   +TA V + ++D ND+PP+F
Sbjct: 1117 QARDSGQ--------PMLYSTAVVSVRVEDANDNPPLF 1206

 Score = 85.5 bits (210), Expect(2) = 5e-24,   Method: Compositional matrix adjust.
 Identities = 76/241 (31%), Positives = 113/241 (46%), Gaps = 11/241 (4%)
 Frame = +3

Query: 643 LQATDR-----EGDPITYAIENGDPQRVFNLSETTGILSLGKALDRESTDRYILIVTASD 697
           +QA+DR     +   ITY ++ G     F L + +GIL    ALDRE+  RY L VTA+D
Sbjct: 9   IQASDRDEASTQNARITYTLD-GQGADHFMLEKDSGILRTAAALDRETQQRYHLEVTATD 185

Query: 698 GRPDGTSXXXXXXXXXXXXXXXP-VFDPYLPRNLSVVEE-EANAFVGQVRATDPDAGING 755
           G   G S               P  F   L   L+V E+   N  + +V   D D GIN 
Sbjct: 186 G--GGLSCVTEVQIFLRDVNDXPPEFTDSLRDTLTVQEDARVNTLLTRVTTVDKDTGINR 359

Query: 756 QVHYSLGNFN-NLFRITSNGSIYTAV-KLNREARDHYELVVVATDGAVHPRHSTLTLYIK 813
              Y L     ++F I     I + V  L+RE    Y++ +VA +       +T  L + 
Sbjct: 360 NTRYELMQREPSVFSIEPKSGILSLVGSLDREEHPQYDVTIVAYNEISPALSATTVLKVV 539

Query: 814 VLDIDDNSPVFTNSTYTVVVEENLPAGTSFLQIEAKDVDLGAN--VSYRIRSPEVKHLFA 871
           VLD++DN P F  ++Y   V E+   GT   ++ A  +D+GAN  ++Y I +   +  F 
Sbjct: 540 VLDVNDNPPTFERTSYYAAVAEDAGVGTVVGRVRATSLDIGANAAITYSIAAGNQQGKFV 719

Query: 872 L 872
           +
Sbjct: 720 I 722

 Score = 45.8 bits (107), Expect(2) = 5e-24,   Method: Compositional matrix adjust.
 Identities = 43/156 (27%), Positives = 74/156 (47%), Gaps = 1/156 (0%)
 Frame = +1

Query: 877  GELSLLRSLDYEAFPDQEASITFLVEAFDIYGTMP-PGIATVTVIVKDMNDYPPVFSKRI 935
            GE+ +   LD+E    +E  +T L      +G+ P    A +++ + D+ND PP FS+  
Sbjct: 736  GEIKVSEPLDHEV--SREYFLTILARD---HGSPPLSNTAIISINITDINDNPPRFSQDT 900

Query: 936  YKGMVAPDAVKGTPITTVYAEDADPPGMPASRVRYRVDDVQFPYPASIFDVEEDSGRVVT 995
            Y   V+   + GT +  V A DAD      S + Y + D       S + + +  G +  
Sbjct: 901  YATTVSEVVLVGTEVFKVMATDAD--SYANSVITYSIIDGNPVRQLSDWVLRD--GIIQV 1068

Query: 996  RVNLNEEPTTIFKLVVVAFDDGEPVMSSSATVRILV 1031
              +L+ E    + L + A D G+P++ S+A V + V
Sbjct: 1069 AKHLDRESVERYALTIQARDSGQPMLYSTAVVSVRV 1176

 Score = 68.9 bits (167), Expect(2) = 3e-21,   Method: Compositional matrix adjust.
 Identities = 69/252 (27%), Positives = 119/252 (47%), Gaps = 9/252 (3%)
 Frame = +3

Query: 846  IEAKDVDLG----ANVSYRIRSPEVKHLFALHPFTGELSLLRSLDYEAFPDQEASITFLV 901
            I+A D D      A ++Y +      H F L   +G   +LR+    A  D+E    + +
Sbjct: 9    IQASDRDEASTQNARITYTLDGQGADH-FMLEKDSG---ILRT---AAALDRETQQRYHL 167

Query: 902  EAFDIYGTMPPGIATVTVIVKDMNDYPPVFSKRIYKGM-VAPDAVKGTPITTVYAEDADP 960
            E     G     +  V + ++D+ND PP F+  +   + V  DA   T +T V   D D 
Sbjct: 168  EVTATDGGGLSCVTEVQIFLRDVNDXPPEFTDSLRDTLTVQEDARVNTLLTRVTTVDKDT 347

Query: 961  PGMPASRVRYRVDDVQFPYPASIFDVEEDSGRVVTRVNLNEEPTTIFKLVVVAFDDGEPV 1020
             G+  +  RY +         S+F +E  SG +    +L+ E    + + +VA+++  P 
Sbjct: 348  -GINRN-TRYEL----MQREPSVFSIEPKSGILSLVGSLDREEHPQYDVTIVAYNEISPA 509

Query: 1021 MSSSATVRILVLHPGEIPRFTQEEYRPPPVSELAARGTVVGVISAAAI----NQSIVYSI 1076
            +S++  ++++VL   + P   +       V+E A  GTVVG + A ++    N +I YSI
Sbjct: 510  LSATTVLKVVVLDVNDNPPTFERTSYYAAVAEDAGVGTVVGRVRATSLDIGANAAITYSI 689

Query: 1077 VAGNEEDKFGIN 1088
             AGN++ KF I+
Sbjct: 690  AAGNQQGKFVID 725

 Score = 53.1 bits (126), Expect(2) = 3e-21,   Method: Compositional matrix adjust.
 Identities = 36/98 (36%), Positives = 48/98 (48%)
 Frame = +1

Query: 1092 GVIYVNSPLDYETRTSYVLRVQADSLEVVLANLRVPSKSNTAKVYIEIQDENDHPPVFQK 1151
            G I V+ PLD+E    Y L + A        +   P  SNTA + I I D ND+PP F +
Sbjct: 736  GEIKVSEPLDHEVSREYFLTILA-------RDHGSPPLSNTAIISINITDINDNPPRFSQ 894

Query: 1152 KFYIGGVSEDARMFASVLRVKATDRDTGNYSAMAYRLI 1189
              Y   VSE   +   V +V ATD D+   S + Y +I
Sbjct: 895  DTYATTVSEVVLVGTEVFKVMATDADSYANSVITYSII 1008

 Score = 67.8 bits (164), Expect = 4e-11,   Method: Compositional matrix adjust.
 Identities = 72/257 (28%), Positives = 115/257 (44%), Gaps = 5/257 (1%)
 Frame = +3

Query: 952  TVYAEDADPPGMPASRVRYRVDDVQFPYPASIFDVEEDSGRVVTRVNLNEEPTTIFKLVV 1011
            T+ A D D      +R+ Y +D       A  F +E+DSG + T   L+ E    + L V
Sbjct: 6    TIQASDRDEASTQNARITYTLD----GQGADHFMLEKDSGILRTAAALDRETQQRYHLEV 173

Query: 1012 VAFDDGEPVMSSSATVRILVLHPGEIP-RFTQEEYRPPPVSELAARGTVVGVISA----A 1066
             A D G   +S    V+I +    + P  FT        V E A   T++  ++      
Sbjct: 174  TATDGGG--LSCVTEVQIFLRDVNDXPPEFTDSLRDTLTVQEDARVNTLLTRVTTVDKDT 347

Query: 1067 AINQSIVYSIVAGNEEDKFGINNVTGVIYVNSPLDYETRTSYVLRVQADSLEVVLANLRV 1126
             IN++  Y ++   E   F I   +G++ +   LD E    Y        + +V  N   
Sbjct: 348  GINRNTRYELMQ-REPSVFSIEPKSGILSLVGSLDREEHPQY-------DVTIVAYNEIS 503

Query: 1127 PSKSNTAKVYIEIQDENDHPPVFQKKFYIGGVSEDARMFASVLRVKATDRDTGNYSAMAY 1186
            P+ S T  + + + D ND+PP F++  Y   V+EDA +   V RV+AT  D G  +A+ Y
Sbjct: 504  PALSATTVLKVVVLDVNDNPPTFERTSYYAAVAEDAGVGTVVGRVRATSLDIGANAAITY 683

Query: 1187 RLIIPPIKEGKEGFVVE 1203
              I    ++GK  FV++
Sbjct: 684  S-IAAGNQQGK--FVID 725

 Score = 62.0 bits (149), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 46/156 (29%), Positives = 76/156 (48%), Gaps = 6/156 (3%)
 Frame = +1

Query: 472 QPVDREEQQTYTFLITAFDGVQE--SEPVVVNIRVMDANDNTPTFPEISYDVYVYTDMSP 529
           +P+D E  + Y   I A D      S   +++I + D NDN P F + +Y   V   +  
Sbjct: 754 EPLDHEVSREYFLTILARDHGSPPLSNTAIISINITDINDNPPRFSQDTYATTVSEVVLV 933

Query: 530 GDSVIQLTAVDADEGSNGEISYEILVGGK----GDFVINKTTGLVSIAPGVELIVGQTYA 585
           G  V ++ A DAD  +N  I+Y I+ G       D+V+    G++ +A  ++    + YA
Sbjct: 934 GTEVFKVMATDADSYANSVITYSIIDGNPVRQLSDWVLRD--GIIQVAKHLDRESVERYA 1107

Query: 586 LTVQASDNAPPAERRHSICTVYIEVLPPNNQSPPRF 621
           LT+QA D+  P     ++ +V +E     N +PP F
Sbjct: 1108LTIQARDSGQPMLYSTAVVSVRVE---DANDNPPLF 1206

 Score = 49.7 bits (117), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 37/108 (34%), Positives = 52/108 (48%), Gaps = 1/108 (0%)
 Frame = +1

Query: 138 VRIVVRDRNDNSPTFKHESYYATVNELTPVGTTIFTGFSGDNGATDIDDGPNGQIEY-VI 196
           + I + D NDN P F  ++Y  TV+E+  VGT +F        ATD D   N  I Y +I
Sbjct: 844 ISINITDINDNPPRFSQDTYATTVSEVVLVGTEVFKVM-----ATDADSYANSVITYSII 1008

Query: 197 QYNPEDPTSNDTFEIPLMLTGNVVLRKRLNYEDKTRYYVIIQANDRAQ 244
             NP    S+      ++  G + + K L+ E   RY + IQA D  Q
Sbjct: 1009DGNPVRQLSD-----WVLRDGIIQVAKHLDRESVERYALTIQARDSGQ 1137

 Score = 48.1 bits (113), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 46/170 (27%), Positives = 76/170 (44%), Gaps = 7/170 (4%)
 Frame = +1

Query: 666 FNLSETTGILSLGKALDRESTDRYILIVTASD-GRPDGTSXXXXXXXXXXXXXXXPVF-- 722
            +L    G + + + LD E +  Y L + A D G P  ++               P F  
Sbjct: 715 LSLMLKNGEIKVSEPLDHEVSREYFLTILARDHGSPPLSNTAIISINITDINDNPPRFSQ 894

Query: 723 DPYLPRNLSVVEEEANAFVGQVRATDPDAGINGQVHYSLGNFNNLFRITS----NGSIYT 778
           D Y      VV      F  +V ATD D+  N  + YS+ + N + +++     +G I  
Sbjct: 895 DTYATTVSEVVLVGTEVF--KVMATDADSYANSVITYSIIDGNPVRQLSDWVLRDGIIQV 1068

Query: 779 AVKLNREARDHYELVVVATDGAVHPRHSTLTLYIKVLDIDDNSPVFTNST 828
           A  L+RE+ + Y L + A D      +ST  + ++V D +DN P+F ++T
Sbjct: 1069AKHLDRESVERYALTIQARDSGQPMLYSTAVVSVRVEDANDNPPLFASNT 1218

 Score = 46.2 bits (108), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 27/59 (45%), Positives = 33/59 (55%)
 Frame = +3

Query: 138 VRIVVRDRNDNSPTFKHESYYATVNELTPVGTTIFTGFSGDNGATDIDDGPNGQIEYVI 196
           +++VV D NDN PTF+  SYYA V E   VGT +     G   AT +D G N  I Y I
Sbjct: 528 LKVVVLDVNDNPPTFERTSYYAAVAEDAGVGTVV-----GRVRATSLDIGANAAITYSI 689

 Score = 45.4 bits (106), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 50/201 (24%), Positives = 81/201 (40%), Gaps = 1/201 (0%)
 Frame = +3

Query: 1065 AAAINQSIVYSIVAGNEEDKFGINNVTGVIYVNSPLDYETRTSYVLRVQADSLEVVLANL 1124
            A+  N  I Y++  G   D F +   +G++   + LD ET+  Y L V A          
Sbjct: 33   ASTQNARITYTL-DGQGADHFMLEKDSGILRTAAALDRETQQRYHLEVTATD-------- 185

Query: 1125 RVPSKSNTAKVYIEIQDENDHPPVFQKKFY-IGGVSEDARMFASVLRVKATDRDTGNYSA 1183
                 S   +V I ++D ND PP F         V EDAR+   + RV   D+DTG    
Sbjct: 186  -GGGLSCVTEVQIFLRDVNDXPPEFTDSLRDTLTVQEDARVNTLLTRVTTVDKDTGINRN 362

Query: 1184 MAYRLIIPPIKEGKEGFVVETYTGLIKTAMLFHNMRRSYFKFQVIATDDYGKGLSGKADV 1243
              Y L    ++     F +E  +G++             +   ++A ++    LS    +
Sbjct: 363  TRYEL----MQREPSVFSIEPKSGILSLVGSLDREEHPQYDVTIVAYNEISPALSATTVL 530

Query: 1244 LVSVVNQLDMQVIVSNVPPTL 1264
             V V++       V++ PPT 
Sbjct: 531  KVVVLD-------VNDNPPTF 572
>17709
          Length = 812

 Score = 89.7 bits (221), Expect = 1e-17,   Method: Compositional matrix adjust.
 Identities = 68/219 (31%), Positives = 108/219 (49%), Gaps = 7/219 (3%)
 Frame = -3

Query: 465 TRYLTLLQPVDREEQQTYTFLITAFDGVQE--SEPVVVNIRVMDANDNTPTFPEISYDVY 522
           T  +T LQ +DRE   +Y+  + A DG     S    + + V D NDN P F   SY V 
Sbjct: 669 TGRVTTLQTLDREAVPSYSIKVIAKDGGSPALSSTATILLTVKDRNDNMPQFHPDSYYVT 490

Query: 523 VYTDMSPGDSVIQLTAVDADEGSNGEISYEILVGGKGDFVINKTTGLVSIAPGVELIVGQ 582
           V+   + G  V+Q++A D D GS G +SY  +      F I+  TG+++    +      
Sbjct: 489 VFETDAAGAKVVQVSASDKDAGSFGRVSYRFIGTTFSIFSIDSNTGVITTTNVLRRASRS 310

Query: 583 TYALTVQASDNAPPAERRHSICTVYIEVLPPNNQSPPRFPQLMYSLEVSE-----AMRIG 637
           +Y LTV A+D   P     +  TV +  L   + + P F       E++E     A  +G
Sbjct: 309 SYQLTVGANDGRSPQLSVRASVTVIVARL---DGTAPAFTSQTKVFEITEDFGVQASSLG 139

Query: 638 AILLNLQATDREGDPITYAIENGDPQRVFNLSETTGILS 676
             +  +QAT   G+ ITY I +GDP +VF + +++G+++
Sbjct: 138 QTVGQVQATGGVGNTITYFITDGDPFQVFAI-DSSGVIT 25

 Score = 65.5 bits (158), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 66/230 (28%), Positives = 105/230 (45%), Gaps = 1/230 (0%)
 Frame = -3

Query: 1091 TGVIYVNSPLDYETRTSYVLRVQADSLEVVLANLRVPSKSNTAKVYIEIQDENDHPPVFQ 1150
            TG +     LD E   SY       S++V+  +   P+ S+TA + + ++D ND+ P F 
Sbjct: 669  TGRVTTLQTLDREAVPSY-------SIKVIAKDGGSPALSSTATILLTVKDRNDNMPQFH 511

Query: 1151 KKFYIGGVSEDARMFASVLRVKATDRDTGNYSAMAYRLIIPPIKEGKEGFVVETYTGLIK 1210
               Y   V E     A V++V A+D+D G++  ++YR I          F +++ TG+I 
Sbjct: 510  PDSYYVTVFETDAAGAKVVQVSASDKDAGSFGRVSYRFIGTTFSI----FSIDSNTGVIT 343

Query: 1211 TAMLFHNMRRSYFKFQVIATDDYGKGLSGKADVLVSVVNQLDMQVIVSNVPPTLVEKKIE 1270
            T  +     RS ++  V A D     LS +A V V +V +LD        P    + K+ 
Sbjct: 342  TTNVLRRASRSSYQLTVGANDGRSPQLSVRASVTV-IVARLD-----GTAPAFTSQTKVF 181

Query: 1271 DLTEILDRYVQEQIPGAKV-VVESIGARRHGDAYSLEDYSKCDLTVYAID 1319
            ++TE  D  VQ    G  V  V++ G   +   Y + D       V+AID
Sbjct: 180  EITE--DFGVQASSLGQTVGQVQATGGVGNTITYFITDGDP--FQVFAID 43

 Score = 60.8 bits (146), Expect = 6e-09,   Method: Compositional matrix adjust.
 Identities = 65/212 (30%), Positives = 97/212 (45%), Gaps = 11/212 (5%)
 Frame = -3

Query: 672 TGILSLGKALDRESTDRYILIVTASDG-RPDGTSXXXXXXXXXXXXXXXPVF--DPYLPR 728
           TG ++  + LDRE+   Y + V A DG  P  +S               P F  D Y   
Sbjct: 669 TGRVTTLQTLDREAVPSYSIKVIAKDGGSPALSSTATILLTVKDRNDNMPQFHPDSYY-- 496

Query: 729 NLSVVE-EEANAFVGQVRATDPDAGINGQVHYS-LGNFNNLFRITSN-GSIYTAVKLNRE 785
            ++V E + A A V QV A+D DAG  G+V Y  +G   ++F I SN G I T   L R 
Sbjct: 495 -VTVFETDAAGAKVVQVSASDKDAGSFGRVSYRFIGTTFSIFSIDSNTGVITTTNVLRRA 319

Query: 786 ARDHYELVVVATDGAVHPRHSTLTLYIKVLDIDDNSPVFTNSTYTVVVEENLPAGTSFL- 844
           +R  Y+L V A DG         ++ + V  +D  +P FT+ T    + E+     S L 
Sbjct: 318 SRSSYQLTVGANDGRSPQLSVRASVTVIVARLDGTAPAFTSQTKVFEITEDFGVQASSLG 139

Query: 845 ----QIEAKDVDLGANVSYRIRSPEVKHLFAL 872
               Q++A    +G  ++Y I   +   +FA+
Sbjct: 138 QTVGQVQATG-GVGNTITYFITDGDPFQVFAI 46

 Score = 58.5 bits (140), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 51/163 (31%), Positives = 74/163 (45%), Gaps = 2/163 (1%)
 Frame = -3

Query: 774 GSIYTAVKLNREARDHYELVVVATDGAVHPRHSTLTLYIKVLDIDDNSPVFTNSTYTVVV 833
           G + T   L+REA   Y + V+A DG      ST T+ + V D +DN P F   +Y V V
Sbjct: 666 GRVTTLQTLDREAVPSYSIKVIAKDGGSPALSSTATILLTVKDRNDNMPQFHPDSYYVTV 487

Query: 834 EENLPAGTSFLQIEAKDVDLGA--NVSYRIRSPEVKHLFALHPFTGELSLLRSLDYEAFP 891
            E   AG   +Q+ A D D G+   VSYR        +F++   TG ++    L   +  
Sbjct: 486 FETDAAGAKVVQVSASDKDAGSFGRVSYRFIGTTFS-IFSIDSNTGVITTTNVLRRAS-- 316

Query: 892 DQEASITFLVEAFDIYGTMPPGIATVTVIVKDMNDYPPVFSKR 934
              +S    V A D         A+VTVIV  ++   P F+ +
Sbjct: 315 --RSSYQLTVGANDGRSPQLSVRASVTVIVARLDGTAPAFTSQ 193

 Score = 52.0 bits (123), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 53/188 (28%), Positives = 87/188 (46%), Gaps = 4/188 (2%)
 Frame = -3

Query: 986  VEEDSGRVVTRVNLNEEPTTIFKLVVVAFDDGEPVMSSSATVRILVLHPGE-IPRFTQEE 1044
            V+ ++GRV T   L+ E    + + V+A D G P +SS+AT+ + V    + +P+F  + 
Sbjct: 681  VDRNTGRVTTLQTLDREAVPSYSIKVIAKDGGSPALSSTATILLTVKDRNDNMPQFHPDS 502

Query: 1045 YRPPPVSELAARGTVVGVISA---AAINQSIVYSIVAGNEEDKFGINNVTGVIYVNSPLD 1101
            Y        AA   VV V ++   A     + Y  + G     F I++ TGVI   + L 
Sbjct: 501  YYVTVFETDAAGAKVVQVSASDKDAGSFGRVSYRFI-GTTFSIFSIDSNTGVITTTNVLR 325

Query: 1102 YETRTSYVLRVQADSLEVVLANLRVPSKSNTAKVYIEIQDENDHPPVFQKKFYIGGVSED 1161
              +R+SY L V A+       + R P  S  A V + +   +   P F  +  +  ++ED
Sbjct: 324  RASRSSYQLTVGAN-------DGRSPQLSVRASVTVIVARLDGTAPAFTSQTKVFEITED 166

Query: 1162 ARMFASVL 1169
              + AS L
Sbjct: 165  FGVQASSL 142

 Score = 45.1 bits (105), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 55/225 (24%), Positives = 93/225 (41%), Gaps = 11/225 (4%)
 Frame = -3

Query: 563 INKTTGLVSIAPGVELIVGQTYALTVQASDNAPPAERRHSICTVYIEVLPPNNQSPPRFP 622
           +++ TG V+    ++     +Y++ V A D   PA    S  T+ + V   N+  P   P
Sbjct: 681 VDRNTGRVTTLQTLDREAVPSYSIKVIAKDGGSPA--LSSTATILLTVKDRNDNMPQFHP 508

Query: 623 QLMYSLEVSEAMRIGAILLNLQATDREGDP---ITYAIENGDPQRVFNLSETTGILSLGK 679
              Y + V E    GA ++ + A+D++      ++Y    G    +F++   TG+++   
Sbjct: 507 DSYY-VTVFETDAAGAKVVQVSASDKDAGSFGRVSYRFI-GTTFSIFSIDSNTGVITTTN 334

Query: 680 ALDRESTDRYILIVTASDGR-PDGTSXXXXXXXXXXXXXXXPVFDPY-----LPRNLSVV 733
            L R S   Y L V A+DGR P  +                P F        +  +  V 
Sbjct: 333 VLRRASRSSYQLTVGANDGRSPQLSVRASVTVIVARLDGTAPAFTSQTKVFEITEDFGVQ 154

Query: 734 EEEANAFVGQVRATDPDAGINGQVHYSL--GNFNNLFRITSNGSI 776
                  VGQV+AT    G+   + Y +  G+   +F I S+G I
Sbjct: 153 ASSLGQTVGQVQAT---GGVGNTITYFITDGDPFQVFAIDSSGVI 28

 Score = 40.0 bits (92), Expect = 0.010,   Method: Compositional matrix adjust.
 Identities = 34/113 (30%), Positives = 52/113 (46%), Gaps = 1/113 (0%)
 Frame = -3

Query: 138 VRIVVRDRNDNSPTFKHESYYATVNELTPVGTTIFTGFSGDNGATDIDDGPNGQIEYVIQ 197
           + + V+DRNDN P F  +SYY TV E    G  +         A+D D G  G++ Y   
Sbjct: 558 ILLTVKDRNDNMPQFHPDSYYVTVFETDAAGAKVV-----QVSASDKDAGSFGRVSYRFI 394

Query: 198 YNPEDPTSNDTFEIPLMLTGNVVLRKRLNYEDKTRYYVIIQAND-RAQNLNER 249
                  S D+    ++ T NV+ R       ++ Y + + AND R+  L+ R
Sbjct: 393 GTTFSIFSIDS-NTGVITTTNVLRR-----ASRSSYQLTVGANDGRSPQLSVR 253
>29507
          Length = 1143

 Score = 88.2 bits (217), Expect = 3e-17,   Method: Compositional matrix adjust.
 Identities = 103/365 (28%), Positives = 165/365 (45%), Gaps = 19/365 (5%)
 Frame = +2

Query: 844  LQIEAKDVDLGAN--VSYRI--RSPEVKHLFALHPFTGELSLLRSLDYEAFPDQEASITF 899
            +Q++A D D G N  + Y I  ++    H F + P TG + + R LDYE     +++ T 
Sbjct: 2    IQVQATDRDSGPNGRIRYSIDNKTDPSGH-FRIDPDTGVVRINRPLDYET----QSTFTL 166

Query: 900  LVEAFDIYGTMPPGIATVTVIVKDMNDYPP----VFSKRIYKGM-VAPDAVKGTPITTVY 954
             +EA D   T   G A + V ++++N+ P     VF +   +   +  +  +GT +  + 
Sbjct: 167  TLEATDHGPTRLVGNAALEVTLENINEQPANIRLVFLQSPGREQHIMENTREGTLVARIS 346

Query: 955  AEDADPPGMPASRVRYRVDDVQFPYPASIFDVEEDSGR---VVTRVNLNEEPTTIFKLVV 1011
             +D D      S  R+   DV       IF ++   G    VV     + E  + + L V
Sbjct: 347  IDDPD-----ISADRHDDVDVNLFGGDDIFGLQVSEGSLSLVVVNSPPDRENKSSYLLTV 511

Query: 1012 VAFDDGEPVMSSSATVRILVLHPGE-IPRFTQEEYRPPPVSELAARGTVVGVISA----A 1066
               D G P + +  +  I +    +  P F  E      V E A  GT V  ++A    A
Sbjct: 512  TVTDSGTPPLHARQSFTIYIDDENDNAPTF--EGSYEGEVPETADIGTFVVKVTASDRDA 685

Query: 1067 AINQSIVYSIVAGNEEDK--FGINNVTGVIYVNSPLDYETRTSYVLRVQADSLEVVLANL 1124
              N  + YSI +G+      F I++ TGVI   +P+D E     VL        VV  + 
Sbjct: 686  GDNARLSYSIESGSSPQAVWFAIDSKTGVITTQTPIDCEVNARPVL-------TVVARDH 844

Query: 1125 RVPSKSNTAKVYIEIQDENDHPPVFQKKFYIGGVSEDARMFASVLRVKATDRDTGNYSAM 1184
             VPS S +  V + ++D ND  P F   FY   V+EDA + +  ++V ATD + G  S +
Sbjct: 845  GVPSLSGSTSVVVTVRDVNDKQPEFDTSFYNARVAEDAAVLSCPVKVHATDPECGATSPV 1024

Query: 1185 AYRLI 1189
            +Y+L+
Sbjct: 1025 SYQLV 1039

 Score = 85.5 bits (210), Expect = 2e-16,   Method: Compositional matrix adjust.
 Identities = 100/352 (28%), Positives = 147/352 (41%), Gaps = 20/352 (5%)
 Frame = +2

Query: 641 LNLQATDREGDP---ITYAIENG-DPQRVFNLSETTGILSLGKALDRESTDRYILIVTAS 696
           + +QATDR+  P   I Y+I+N  DP   F +   TG++ + + LD E+   + L + A+
Sbjct: 2   IQVQATDRDSGPNGRIRYSIDNKTDPSGHFRIDPDTGVVRINRPLDYETQSTFTLTLEAT 181

Query: 697 DGRPDGTSXXXXXXXXXXXXXXXP-----VFDPYLPRNLSVVEE-EANAFVGQVRATDPD 750
           D  P                   P     VF     R   ++E       V ++   DPD
Sbjct: 182 DHGPTRLVGNAALEVTLENINEQPANIRLVFLQSPGREQHIMENTREGTLVARISIDDPD 361

Query: 751 --AGINGQVHYSLGNFNNLFRI-TSNGSIYTAV---KLNREARDHYELVVVATDGAVHPR 804
             A  +  V  +L   +++F +  S GS+   V     +RE +  Y L V  TD    P 
Sbjct: 362 ISADRHDDVDVNLFGGDDIFGLQVSEGSLSLVVVNSPPDRENKSSYLLTVTVTDSGTPPL 541

Query: 805 HSTLTLYIKVLDIDDNSPVFTNSTYTVVVEENLPAGTSFLQIEAKDVDLGAN--VSYRIR 862
           H+  +  I + D +DN+P F  S Y   V E    GT  +++ A D D G N  +SY I 
Sbjct: 542 HARQSFTIYIDDENDNAPTFEGS-YEGEVPETADIGTFVVKVTASDRDAGDNARLSYSIE 718

Query: 863 SPEVKH--LFALHPFTGELSLLRSLDYEAFPDQEASITFLVEAFDIYGTMPPGIATVTVI 920
           S        FA+   TG ++    +D E      A     V A D       G  +V V 
Sbjct: 719 SGSSPQAVWFAIDSKTGVITTQTPIDCEV----NARPVLTVVARDHGVPSLSGSTSVVVT 886

Query: 921 VKDMNDYPPVFSKRIYKGMVAPDAVKGTPITTVYAEDADPPGMPASRVRYRV 972
           V+D+ND  P F    Y   VA DA   +    V+A   DP     S V Y++
Sbjct: 887 VRDVNDKQPEFDTSFYNARVAEDAAVLSCPVKVHA--TDPECGATSPVSYQL 1036

 Score = 77.4 bits (189), Expect = 5e-14,   Method: Compositional matrix adjust.
 Identities = 95/366 (25%), Positives = 155/366 (42%), Gaps = 17/366 (4%)
 Frame = +2

Query: 309 IQAIDQDRNIQPPSDRPGILYSILVGTPEDYPRFFHMHPRTAELTLLEPVNRDFHQKFDL 368
           +QA D+D     P+ R  I YSI   T  D    F + P T  + +  P++ +    F L
Sbjct: 8   VQATDRDSG---PNGR--IRYSIDNKT--DPSGHFRIDPDTGVVRINRPLDYETQSTFTL 166

Query: 369 VIKAEQDNGHPLPAFASLHIEILDENNQSP-----YFTMPSYQGYILESAPVGATISESL 423
            ++A       L   A+L + + + N Q       +   P  + +I+E+   G  ++   
Sbjct: 167 TLEATDHGPTRLVGNAALEVTLENINEQPANIRLVFLQSPGREQHIMENTREGTLVA--- 337

Query: 424 NLTTPLRIVALDKDIEDTK--DPELHLFLNDYTSVFTVTPTGITRYLTLLQPVDREEQQT 481
                 RI   D DI   +  D +++LF  D      V+  G    + +  P DRE + +
Sbjct: 338 ------RISIDDPDISADRHDDVDVNLFGGDDIFGLQVS-EGSLSLVVVNSPPDRENKSS 496

Query: 482 YTFLITAFDGVQESEPV----VVNIRVMDANDNTPTFPEISYDVYVYTDMSPGDSVIQLT 537
           Y   +T  D    + P+       I + D NDN PTF E SY+  V      G  V+++T
Sbjct: 497 YLLTVTVTD--SGTPPLHARQSFTIYIDDENDNAPTF-EGSYEGEVPETADIGTFVVKVT 667

Query: 538 AVDADEGSNGEISYEILVGGKGD---FVINKTTGLVSIAPGVELIVGQTYALTVQASDNA 594
           A D D G N  +SY I  G       F I+  TG+++    ++  V     LTV A D+ 
Sbjct: 668 ASDRDAGDNARLSYSIESGSSPQAVWFAIDSKTGVITTQTPIDCEVNARPVLTVVARDHG 847

Query: 595 PPAERRHSICTVYIEVLPPNNQSPPRFPQLMYSLEVSEAMRIGAILLNLQATDREG---D 651
            P+    +   V +  +   N   P F    Y+  V+E   + +  + + ATD E     
Sbjct: 848 VPSLSGSTSVVVTVRDV---NDKQPEFDTSFYNARVAEDAAVLSCPVKVHATDPECGATS 1018

Query: 652 PITYAI 657
           P++Y +
Sbjct: 1019PVSYQL 1036

 Score = 57.4 bits (137), Expect = 6e-08,   Method: Compositional matrix adjust.
 Identities = 92/391 (23%), Positives = 152/391 (38%), Gaps = 17/391 (4%)
 Frame = +2

Query: 181 ATDIDDGPNGQIEYVIQYNPEDPTSNDTFEIPLMLTGNVVLRKRLNYEDKTRYYVIIQAN 240
           ATD D GPNG+I Y I  N  DP+ +  F I    TG V + + L+YE ++ + + ++A 
Sbjct: 14  ATDRDSGPNGRIRYSID-NKTDPSGH--FRIDPD-TGVVRINRPLDYETQSTFTLTLEAT 181

Query: 241 DRAQNLNERRXXXXXXXXXXXXXXXXXPMFLPCVLVPNTRDCRPLTYQAAIPELRTPEEL 300
           D        R                 P  +  V + +     P   Q  +   R    +
Sbjct: 182 DHGPT----RLVGNAALEVTLENINEQPANIRLVFLQS-----PGREQHIMENTREGTLV 334

Query: 301 NPILVTPPIQAIDQDRNIQPPSDRPGILYSILVGTPEDYPRFFHMHPRTAELTLL---EP 357
             I +  P  + D+  ++             L G  +     F +      L+L+    P
Sbjct: 335 ARISIDDPDISADRHDDVDVN----------LFGGDD----IFGLQVSEGSLSLVVVNSP 472

Query: 358 VNRDFHQKFDLVIKAEQDNGHPLPAFASLHIEILDENNQSPYFTMPSYQGYILESAPVGA 417
            +R+    + L +        PL A  S  I I DEN+ +P F   SY+G + E+A +G 
Sbjct: 473 PDRENKSSYLLTVTVTDSGTPPLHARQSFTIYIDDENDNAPTFEG-SYEGEVPETADIGT 649

Query: 418 TISESLNLTTPLRIVALDKD----------IEDTKDPELHLFLNDYTSVFTVTPTGITRY 467
            +         +++ A D+D          IE    P+   F  D       + TG+   
Sbjct: 650 FV---------VKVTASDRDAGDNARLSYSIESGSSPQAVWFAID-------SKTGV--- 772

Query: 468 LTLLQPVDREEQQTYTFLITAFD----GVQESEPVVVNIRVMDANDNTPTFPEISYDVYV 523
           +T   P+D E        + A D     +  S  VVV +R  D ND  P F    Y+  V
Sbjct: 773 ITTQTPIDCEVNARPVLTVVARDHGVPSLSGSTSVVVTVR--DVNDKQPEFDTSFYNARV 946

Query: 524 YTDMSPGDSVIQLTAVDADEGSNGEISYEIL 554
             D +     +++ A D + G+   +SY+++
Sbjct: 947 AEDAAVLSCPVKVHATDPECGATSPVSYQLV 1039

 Score = 32.0 bits (71), Expect = 2.4,   Method: Compositional matrix adjust.
 Identities = 22/58 (37%), Positives = 30/58 (51%)
 Frame = +2

Query: 140 IVVRDRNDNSPTFKHESYYATVNELTPVGTTIFTGFSGDNGATDIDDGPNGQIEYVIQ 197
           I + D NDN+PTF+  SY   V E   +GT     F     A+D D G N ++ Y I+
Sbjct: 563 IYIDDENDNAPTFEG-SYEGEVPETADIGT-----FVVKVTASDRDAGDNARLSYSIE 718
>08409
          Length = 890

 Score = 88.2 bits (217), Expect = 3e-17,   Method: Compositional matrix adjust.
 Identities = 83/274 (30%), Positives = 126/274 (45%), Gaps = 8/274 (2%)
 Frame = +3

Query: 946  KGTPITTVYAEDADPPGMPASRVRYRVDDVQFPYPASIFDVEEDSGRVVTRVNLNEEPTT 1005
            +G+ I  V A D D       R++Y     QF  P + F +   SG + T   L+ E   
Sbjct: 117  RGSHIGEVTASDRDAGN--NQRLQY-----QFSVPQTQFAINTYSGEISTLGPLDREQQE 275

Query: 1006 IFKLVVVAFDDGEPVMSSSATVRILVLHPGE-IPRFTQEEYRPPPVSELAARG----TVV 1060
            ++ L V   D G+P +S S  V+I VL   +  P+F ++ YR   V E   +G    TVV
Sbjct: 276  LYTLWVYVTDQGQPELSDSTVVKIEVLDENDNRPKFMEDVYRRS-VEENRPKGLHVLTVV 452

Query: 1061 GVISAAAINQSIVYSIVAGNEED---KFGINNVTGVIYVNSPLDYETRTSYVLRVQADSL 1117
               + A  N ++ +S    ++ D    F I+   G I     LDYET+T Y        L
Sbjct: 453  AQDTDAGENGTVTFSFHRDSDADALTHFSIHAAKGWIITEEVLDYETQTQY-------RL 611

Query: 1118 EVVLANLRVPSKSNTAKVYIEIQDENDHPPVFQKKFYIGGVSEDARMFASVLRVKATDRD 1177
             V+  +   P  S++A+V I++ D ND  P+F  +     V E+  +   V  VKA DRD
Sbjct: 612  LVIAHDNGQPRLSSSAEVLIDVADANDEAPLFHAREVTFYVVENVAIGTVVGEVKARDRD 791

Query: 1178 TGNYSAMAYRLIIPPIKEGKEGFVVETYTGLIKT 1211
            +G    + Y L+   +      F V   TG+I+T
Sbjct: 792  SGENGRVTYYLVGGNV---FSLFSVNPATGMIQT 884

 Score = 87.8 bits (216), Expect = 3e-17,   Method: Compositional matrix adjust.
 Identities = 74/241 (30%), Positives = 107/241 (44%), Gaps = 7/241 (2%)
 Frame = +3

Query: 726 LPRNLSVVEEE-ANAFVGQVRATDPDAGINGQVHYSLGNFNNLFRI-TSNGSIYTAVKLN 783
           L + ++++E +   + +G+V A+D DAG N ++ Y        F I T +G I T   L+
Sbjct: 81  LRKQINILENQPRGSHIGEVTASDRDAGNNQRLQYQFSVPQTQFAINTYSGEISTLGPLD 260

Query: 784 REARDHYELVVVATDGAVHPRHSTLTLYIKVLDIDDNSPVFTNSTYTVVVEENLPAGTSF 843
           RE ++ Y L V  TD        +  + I+VLD +DN P F    Y   VEEN P G   
Sbjct: 261 REQQELYTLWVYVTDQGQPELSDSTVVKIEVLDENDNRPKFMEDVYRRSVEENRPKGLHV 440

Query: 844 LQIEAKDVDLGANVS-----YRIRSPEVKHLFALHPFTGELSLLRSLDYEAFPDQEASIT 898
           L + A+D D G N +     +R    +    F++H   G +     LDYE     +    
Sbjct: 441 LTVVAQDTDAGENGTVTFSFHRDSDADALTHFSIHAAKGWIITEEVLDYET----QTQYR 608

Query: 899 FLVEAFDIYGTMPPGIATVTVIVKDMNDYPPVFSKRIYKGMVAPDAVKGTPITTVYAEDA 958
            LV A D         A V + V D ND  P+F  R     V  +   GT +  V A D 
Sbjct: 609 LLVIAHDNGQPRLSSSAEVLIDVADANDEAPLFHAREVTFYVVENVAIGTVVGEVKARDR 788

Query: 959 D 959
           D
Sbjct: 789 D 791

 Score = 47.0 bits (110), Expect = 8e-05,   Method: Compositional matrix adjust.
 Identities = 33/107 (30%), Positives = 51/107 (47%)
 Frame = +3

Query: 138 VRIVVRDRNDNSPTFKHESYYATVNELTPVGTTIFTGFSGDNGATDIDDGPNGQIEYVIQ 197
           V+I V D NDN P F  + Y  +V E  P G  + T       A D D G NG + +   
Sbjct: 339 VKIEVLDENDNRPKFMEDVYRRSVEENRPKGLHVLTVV-----AQDTDAGENGTVTFSF- 500

Query: 198 YNPEDPTSNDTFEIPLMLTGNVVLRKRLNYEDKTRYYVIIQANDRAQ 244
           +   D  +   F I     G ++  + L+YE +T+Y +++ A+D  Q
Sbjct: 501 HRDSDADALTHFSIHAA-KGWIITEEVLDYETQTQYRLLVIAHDNGQ 638
>19661
          Length = 684

 Score = 83.2 bits (204), Expect = 9e-16,   Method: Compositional matrix adjust.
 Identities = 64/227 (28%), Positives = 107/227 (47%), Gaps = 13/227 (5%)
 Frame = +1

Query: 358 VNRDFHQKFDLVIKAEQDNGHPLPAFASLHIEIL--DENNQSPYFTMPSYQGYILESAPV 415
           ++R+  +++ LV++A   +     ++A +H+ ++  D N+ SP F    Y   + E A V
Sbjct: 58  LDRESQERYQLVLRASDVSS---ASYADMHLTVILQDVNDNSPVFESLRYTHTVSEVARV 228

Query: 416 GATISE--------SLNLTTPLRIVALDKDIEDTKDPELHLFLNDYTSVFTVTPTGITRY 467
           G +I +        + N      +  L  D  DT+              F  + TG    
Sbjct: 229 GTSILQVAARDXDBAANSLIHYSLAPLSADSADTQ------------PFFVHSETGT--- 363

Query: 468 LTLLQPVDREEQQTYTFLITAFDGVQ--ESEPVVVNIRVMDANDNTPTFPEISYDVYVYT 525
           + L +P+D E Q  YTFL  A D      S   +V+I V+D NDN P F ++S++ Y+  
Sbjct: 364 IVLHRPLDHEAQADYTFLAVATDSGMPARSATALVHIIVLDLNDNXPHFTQLSFNCYITD 543

Query: 526 DMSPGDSVIQLTAVDADEGSNGEISYEILVGG-KGDFVINKTTGLVS 571
               G  V ++T +DAD+   G + Y I+ G  K  F IN  +GL++
Sbjct: 544 QAHRGQLVTKVTGMDADDSDKGNLVYSIIGGNEKQAFTINSASGLIT 684

 Score = 78.2 bits (191), Expect = 3e-14,   Method: Compositional matrix adjust.
 Identities = 68/193 (35%), Positives = 104/193 (53%), Gaps = 9/193 (4%)
 Frame = +1

Query: 776 IYTAVKLNREARDHYELVVVATDGAVHPRHSTLTLYIKVLDIDDNSPVFTNSTYTVVVEE 835
           +  A +L+RE+++ Y+LV+ A+D +    ++ + L + + D++DNSPVF +  YT  V E
Sbjct: 40  VLVAGQLDRESQERYQLVLRASDVS-SASYADMHLTVILQDVNDNSPVFESLRYTHTVSE 216

Query: 836 NLPAGTSFLQIEAKDVDLGAN--VSYRIR-----SPEVKHLFALHPFTGELSLLRSLDYE 888
               GTS LQ+ A+D D  AN  + Y +      S + +  F +H  TG + L R LD+E
Sbjct: 217 VARVGTSILQVAARDXDBAANSLIHYSLAPLSADSADTQPFF-VHSETGTIVLHRPLDHE 393

Query: 889 AFPDQEASITFLVEAFDIYGTMPPGIAT--VTVIVKDMNDYPPVFSKRIYKGMVAPDAVK 946
           A    +A  TFL  A D    MP   AT  V +IV D+ND  P F++  +   +   A +
Sbjct: 394 A----QADYTFLAVATD--SGMPARSATALVHIIVLDLNDNXPHFTQLSFNCYITDQAHR 555

Query: 947 GTPITTVYAEDAD 959
           G  +T V   DAD
Sbjct: 556 GQLVTKVTGMDAD 594

 Score = 70.5 bits (171), Expect = 6e-12,   Method: Compositional matrix adjust.
 Identities = 60/188 (31%), Positives = 91/188 (48%), Gaps = 10/188 (5%)
 Frame = +1

Query: 917  VTVIVKDMNDYPPVFSKRIYKGMVAPDAVKGTPITTVYAEDADPPGMPASRVRYRVDDVQ 976
            +TVI++D+ND  PVF    Y   V+  A  GT I  V A D        S + Y +    
Sbjct: 139  LTVILQDVNDNSPVFESLRYTHTVSEVARVGTSILQVAARDX--DBAANSLIHYSL---- 300

Query: 977  FPYPASIFD-----VEEDSGRVVTRVNLNEEPTTIFKLVVVAFDDGEPVMSSSATVRILV 1031
             P  A   D     V  ++G +V    L+ E    +  + VA D G P  S++A V I+V
Sbjct: 301  APLSADSADTQPFFVHSETGTIVLHRPLDHEAQADYTFLAVATDSGMPARSATALVHIIV 480

Query: 1032 LHPGE-IPRFTQEEYRPPPVSELAARGTVVGVISAAAINQS----IVYSIVAGNEEDKFG 1086
            L   +  P FTQ  +    +++ A RG +V  ++    + S    +VYSI+ GNE+  F 
Sbjct: 481  LDLNDNXPHFTQLSFNCY-ITDQAHRGQLVTKVTGMDADDSDKGNLVYSIIGGNEKQAFT 657

Query: 1087 INNVTGVI 1094
            IN+ +G+I
Sbjct: 658  INSASGLI 681

 Score = 64.7 bits (156), Expect = 4e-10,   Method: Compositional matrix adjust.
 Identities = 62/209 (29%), Positives = 91/209 (43%), Gaps = 12/209 (5%)
 Frame = +1

Query: 681 LDRESTDRYILIVTASDGRPDGTSXXXXXXXXXXXXXXXPVFDPYLPRNLSVVEEEA--N 738
           LDRES +RY L++ ASD      +               PVF+    R    V E A   
Sbjct: 58  LDRESQERYQLVLRASDVSSASYADMHLTVILQDVNDNSPVFESL--RYTHTVSEVARVG 231

Query: 739 AFVGQVRATDPDAGINGQVHYSLGNFNN-------LFRITSNGSIYTAVKLNREARDHYE 791
             + QV A D D   N  +HYSL   +         F  +  G+I     L+ EA+  Y 
Sbjct: 232 TSILQVAARDXDBAANSLIHYSLAPLSADSADTQPFFVHSETGTIVLHRPLDHEAQADYT 411

Query: 792 LVVVATDGAVHPRHSTLTLYIKVLDIDDNSPVFTNSTYTVVVEENLPAG---TSFLQIEA 848
            + VATD  +  R +T  ++I VLD++DN P FT  ++   + +    G   T    ++A
Sbjct: 412 FLAVATDSGMPARSATALVHIIVLDLNDNXPHFTQLSFNCYITDQAHRGQLVTKVTGMDA 591

Query: 849 KDVDLGANVSYRIRSPEVKHLFALHPFTG 877
            D D G N+ Y I     K  F ++  +G
Sbjct: 592 DDSDKG-NLVYSIIGGNEKQAFTINSASG 675

 Score = 44.7 bits (104), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 58/231 (25%), Positives = 92/231 (39%), Gaps = 19/231 (8%)
 Frame = +1

Query: 567 TGLVSIAPGVELIVGQT-------YALTVQASDNAPPAERRHSICTVYIEVLPPNNQSPP 619
           T +  + P + L+ GQ        Y L ++ASD +  +     +  +  +V    N + P
Sbjct: 10  TDMDELGPCLVLVAGQLDRESQERYQLVLRASDVSSASYADMHLTVILQDV----NDNSP 177

Query: 620 RFPQLMYSLEVSEAMRIGAILLNL---QATDREGDPITYAI-----ENGDPQRVFNLSET 671
            F  L Y+  VSE  R+G  +L +      B     I Y++     ++ D Q  F  SE 
Sbjct: 178 VFESLRYTHTVSEVARVGTSILQVAARDXDBAANSLIHYSLAPLSADSADTQPFFVHSE- 354

Query: 672 TGILSLGKALDRESTDRYILIVTASD-GRPDGTSXXXXXXXXXXXXXXXPVFDPYLPRNL 730
           TG + L + LD E+   Y  +  A+D G P  ++               P F   L  N 
Sbjct: 355 TGTIVLHRPLDHEAQADYTFLAVATDSGMPARSATALVHIIVLDLNDNXPHF-TQLSFNC 531

Query: 731 SVVEEEANA-FVGQVRATDPDAGINGQVHYSL--GNFNNLFRITSNGSIYT 778
            + ++      V +V   D D    G + YS+  GN    F I S   + T
Sbjct: 532 YITDQAHRGQLVTKVTGMDADDSDKGNLVYSIIGGNEKQAFTINSASGLIT 684

 Score = 41.2 bits (95), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 24/80 (30%), Positives = 41/80 (51%), Gaps = 1/80 (1%)
 Frame = +1

Query: 343 FHMHPRTAELTLLEPVNRDFHQKFDLVIKAEQDNGHPL-PAFASLHIEILDENNQSPYFT 401
           F +H  T  + L  P++ +    +  +  A  D+G P   A A +HI +LD N+  P+FT
Sbjct: 337 FFVHSETGTIVLHRPLDHEAQADYTFLAVAT-DSGMPARSATALVHIIVLDLNDNXPHFT 513

Query: 402 MPSYQGYILESAPVGATISE 421
             S+  YI + A  G  +++
Sbjct: 514 QLSFNCYITDQAHRGQLVTK 573

 Score = 40.0 bits (92), Expect = 0.009,   Method: Compositional matrix adjust.
 Identities = 44/160 (27%), Positives = 74/160 (46%), Gaps = 3/160 (1%)
 Frame = +1

Query: 1093 VIYVNSPLDYETRTSYVLRVQADSLEVVLANLRVPSKSNTAKVYIEI--QDENDHPPVFQ 1150
            ++ V   LD E++  Y L ++A  +          S ++ A +++ +  QD ND+ PVF+
Sbjct: 37   LVLVAGQLDRESQERYQLVLRASDV----------SSASYADMHLTVILQDVNDNSPVFE 186

Query: 1151 KKFYIGGVSEDARMFASVLRVKATDRDTGNYSAMAYRLI-IPPIKEGKEGFVVETYTGLI 1209
               Y   VSE AR+  S+L+V A D D    S + Y L  +       + F V + TG I
Sbjct: 187  SLRYTHTVSEVARVGTSILQVAARDXDBAANSLIHYSLAPLSADSADTQPFFVHSETGTI 366

Query: 1210 KTAMLFHNMRRSYFKFQVIATDDYGKGLSGKADVLVSVVN 1249
                   +  ++ + F  +ATD      S  A V + V++
Sbjct: 367  VLHRPLDHEAQADYTFLAVATDSGMPARSATALVHIIVLD 486

 Score = 38.5 bits (88), Expect = 0.028,   Method: Compositional matrix adjust.
 Identities = 32/109 (29%), Positives = 52/109 (47%), Gaps = 4/109 (3%)
 Frame = +1

Query: 137 EVRIVVRDRNDNSPTFKHESYYATVNELTPVGTTIFTGFSGDNGATDIDDGPNGQIEYVI 196
            + ++++D NDNSP F+   Y  TV+E+  VGT+I    + D          N  I Y +
Sbjct: 136 HLTVILQDVNDNSPVFESLRYTHTVSEVARVGTSILQVAARDXDBA-----ANSLIHYSL 300

Query: 197 QYNPEDPTSNDTFEI-PLML---TGNVVLRKRLNYEDKTRYYVIIQAND 241
                 P S D+ +  P  +   TG +VL + L++E +  Y  +  A D
Sbjct: 301 A-----PLSADSADTQPFFVHSETGTIVLHRPLDHEAQADYTFLAVATD 432
>25641
          Length = 921

 Score = 77.4 bits (189), Expect = 5e-14,   Method: Compositional matrix adjust.
 Identities = 80/276 (28%), Positives = 131/276 (47%), Gaps = 17/276 (6%)
 Frame = +2

Query: 771  TSNGSIYTAVKLNREARDHY-ELVVVATDGAVHPRHSTLT-LYIKVLDIDDNSPVFTNST 828
            ++ G ++ A  L+ E+ D + EL + A+DG     H+  T + + VLD +DN+P F ++ 
Sbjct: 59   SATGGLFVAKTLDYESYDRFFELTLNASDGM----HTASTRVQVTVLDANDNAPEFIDTP 226

Query: 829  YTV---VVEENLPAGTS---FLQIEA--KDVDLGANVSYRIRSPEVK---HLFALHPFTG 877
            Y +   +VEE+    T     L + A  +D D   N+SY ++    +     F + P TG
Sbjct: 227  YRIENRIVEEDKSVTTRPKRLLTVLATDRDTDRPNNISYTLQGYGTEPPNQYFRIDPITG 406

Query: 878  ELSLLRSLDYEAFPDQEASITFLVEAFDI-YGTMPPGIATVTVIVKDMNDYPPVFSKRIY 936
             L +++ LD +  P   ++  F V A D  +     G ATV V+  D+ND  P F     
Sbjct: 407  GLFVIKPLDRDG-PHGRSNYQFTVVARDEPHQPWQFGYATVEVLPADINDNKPTFDATKL 583

Query: 937  KGMVAPDAVKGTPITTVYAEDADPPGMPASRVRYRVDDVQFPYPASIFDVEEDSGRVVTR 996
            KG V   +  GT +  V A D D     +       + V        F ++  SG + T 
Sbjct: 584  KGSVDEHSEPGTSVMFVLATDPDRGNNGSVVYDIIKNSVTVGSKQDYFVIDRQSGLIKTN 763

Query: 997  V---NLNEEPTTIFKLVVVAFDDGEPVMSSSATVRI 1029
            V   +L+ E    F L V A D+G+P ++++AT+ I
Sbjct: 764  VDKRDLDRETIPSFTLEVRASDEGKPPLNTTATITI 871

 Score = 73.9 bits (180), Expect = 5e-13,   Method: Compositional matrix adjust.
 Identities = 91/312 (29%), Positives = 132/312 (42%), Gaps = 29/312 (9%)
 Frame = +2

Query: 653 ITYAIENGD-PQRVFNLSETTGILSLGKALDRESTDRYI-LIVTASDGRPDGTSXXXXXX 710
           + Y I +G+ P   F +   TG L + K LD ES DR+  L + ASDG    ++      
Sbjct: 5   LNYLIVDGNAPLYKFGIKSATGGLFVAKTLDYESYDRFFELTLNASDGMHTASTRVQVTV 184

Query: 711 XXXXXXXXXPVFDPYLPRNLSVVEEEANAFVGQVR-----ATDPDAGINGQVHYSLGNF- 764
                     +  PY   N  +VEE+ +      R     ATD D      + Y+L  + 
Sbjct: 185 LDANDNAPEFIDTPYRIEN-RIVEEDKSVTTRPKRLLTVLATDRDTDRPNNISYTLQGYG 361

Query: 765 ----NNLFRITS-NGSIYTAVKLNREA---RDHYELVVVATDGAVHP-RHSTLTLYIKVL 815
               N  FRI    G ++    L+R+    R +Y+  VVA D    P +    T+ +   
Sbjct: 362 TEPPNQYFRIDPITGGLFVIKPLDRDGPHGRSNYQFTVVARDEPHQPWQFGYATVEVLPA 541

Query: 816 DIDDNSPVFTNSTYTVVVEENLPAGTSFLQIEAKDVDLGAN--VSYRIRSPEV-----KH 868
           DI+DN P F  +     V+E+   GTS + + A D D G N  V Y I    V     + 
Sbjct: 542 DINDNKPTFDATKLKGSVDEHSEPGTSVMFVLATDPDRGNNGSVVYDIIKNSVTVGSKQD 721

Query: 869 LFALHPFTGELSL---LRSLDYEAFPDQEASITFLVEAFDIYGTMPP--GIATVTVIVKD 923
            F +   +G +      R LD E  P    S T  V A D     PP    AT+T+ + D
Sbjct: 722 YFVIDRQSGLIKTNVDKRDLDRETIP----SFTLEVRASD--EGKPPLNTTATITISLSD 883

Query: 924 MNDYPPVFSKRI 935
           +ND  PVF  ++
Sbjct: 884 INDQKPVFDPKV 919

 Score = 65.1 bits (157), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 78/304 (25%), Positives = 135/304 (44%), Gaps = 22/304 (7%)
 Frame = +2

Query: 343 FHMHPRTAELTLLEPVNRDFHQKFDLVIKAEQDNGHPLPAFASLHIEILDENNQSPYFTM 402
           F +   T  L + + ++ + + +F  +     D  H   A   + + +LD N+ +P F  
Sbjct: 47  FGIKSATGGLFVAKTLDYESYDRFFELTLNASDGMHT--ASTRVQVTVLDANDNAPEFID 220

Query: 403 PSYQGYILESAPVGATISESLNLTTPLRIVALDKDIEDTKDPELHLFLNDYTS-----VF 457
             Y+   +E+  V    S +      L ++A D+D +  +   +   L  Y +      F
Sbjct: 221 TPYR---IENRIVEEDKSVTTRPKRLLTVLATDRDTD--RPNNISYTLQGYGTEPPNQYF 385

Query: 458 TVTPTGITRYLTLLQPVDREE---QQTYTFLITAFDGVQESEP-----VVVNIRVMDAND 509
            + P  IT  L +++P+DR+    +  Y F + A D  +  +P       V +   D ND
Sbjct: 386 RIDP--ITGGLFVIKPLDRDGPHGRSNYQFTVVARD--EPHQPWQFGYATVEVLPADIND 553

Query: 510 NTPTFPEISYDVYVYTDMSPGDSVIQLTAVDADEGSNGEISYEIL-----VGGKGD-FVI 563
           N PTF        V     PG SV+ + A D D G+NG + Y+I+     VG K D FVI
Sbjct: 554 NKPTFDATKLKGSVDEHSEPGTSVMFVLATDPDRGNNGSVVYDIIKNSVTVGSKQDYFVI 733

Query: 564 NKTTGLVSIAPGVELIVGQT---YALTVQASDNAPPAERRHSICTVYIEVLPPNNQSPPR 620
           ++ +GL+        +  +T   + L V+ASD   P    ++  T+ I +   N+Q P  
Sbjct: 734 DRQSGLIKTNVDKRDLDRETIPSFTLEVRASDEGKPP--LNTTATITISLSDINDQKPVF 907

Query: 621 FPQL 624
            P++
Sbjct: 908 DPKV 919

 Score = 57.4 bits (137), Expect = 5e-08,   Method: Compositional matrix adjust.
 Identities = 85/293 (29%), Positives = 121/293 (41%), Gaps = 29/293 (9%)
 Frame = +2

Query: 561 FVINKTTGLVSIAPGVEL-IVGQTYALTVQASDNAPPAERRHSICTVYIEVLPPNNQSPP 619
           F I   TG + +A  ++     + + LT+ ASD    A  R     V + VL  N+ +P 
Sbjct: 47  FGIKSATGGLFVAKTLDYESYDRFFELTLNASDGMHTASTR-----VQVTVLDANDNAP- 208

Query: 620 RFPQLMYSLE---VSEAMRIGAI---LLNLQATDREGD---PITYAIENGD---PQRVFN 667
            F    Y +E   V E   +      LL + ATDR+ D    I+Y ++      P + F 
Sbjct: 209 EFIDTPYRIENRIVEEDKSVTTRPKRLLTVLATDRDTDRPNNISYTLQGYGTEPPNQYFR 388

Query: 668 LSETTGILSLGKALDRES---TDRYILIVTASD--GRPDGTSXXXXXXXXXXXXXXXPVF 722
           +   TG L + K LDR+       Y   V A D   +P                   P F
Sbjct: 389 IDPITGGLFVIKPLDRDGPHGRSNYQFTVVARDEPHQPWQFGYATVEVLPADINDNKPTF 568

Query: 723 DPYLPRNLSVVEEEANAFVGQVRATDPDAGINGQVHY-------SLGNFNNLFRIT-SNG 774
           D    +       E    V  V ATDPD G NG V Y       ++G+  + F I   +G
Sbjct: 569 DATKLKGSVDEHSEPGTSVMFVLATDPDRGNNGSVVYDIIKNSVTVGSKQDYFVIDRQSG 748

Query: 775 SIYTAV---KLNREARDHYELVVVATDGAVHPRHSTLTLYIKVLDIDDNSPVF 824
            I T V    L+RE    + L V A+D    P ++T T+ I + DI+D  PVF
Sbjct: 749 LIKTNVDKRDLDRETIPSFTLEVRASDEGKPPLNTTATITISLSDINDQKPVF 907

 Score = 53.9 bits (128), Expect = 6e-07,   Method: Compositional matrix adjust.
 Identities = 51/178 (28%), Positives = 84/178 (47%), Gaps = 8/178 (4%)
 Frame = +2

Query: 1085 FGINNVTGVIYVNSPLDYET---RTSYVLRVQADSLEVVLANLRVPSKSNTAKVYIEIQD 1141
            F I+ +TG ++V  PLD +    R++Y   V      V       P +   A V +   D
Sbjct: 383  FRIDPITGGLFVIKPLDRDGPHGRSNYQFTV------VARDEPHQPWQFGYATVEVLPAD 544

Query: 1142 ENDHPPVFQKKFYIGGVSEDARMFASVLRVKATDRDTGNYSAMAYRLIIPPIKEG--KEG 1199
             ND+ P F      G V E +    SV+ V ATD D GN  ++ Y +I   +  G  ++ 
Sbjct: 545  INDNKPTFDATKLKGSVDEHSEPGTSVMFVLATDPDRGNNGSVVYDIIKNSVTVGSKQDY 724

Query: 1200 FVVETYTGLIKTAMLFHNMRRS---YFKFQVIATDDYGKGLSGKADVLVSVVNQLDMQ 1254
            FV++  +GLIKT +   ++ R     F  +V A+D+    L+  A + +S+ +  D +
Sbjct: 725  FVIDRQSGLIKTNVDKRDLDRETIPSFTLEVRASDEGKPPLNTTATITISLSDINDQK 898

 Score = 50.8 bits (120), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 84/311 (27%), Positives = 130/311 (41%), Gaps = 26/311 (8%)
 Frame = +2

Query: 868  HLFALHPFTGELSLLRSLDYEAFPDQEASITFLVEAFDIYGTMPPGIATVTVIVKDMNDY 927
            + F +   TG L + ++LDYE++        F     +    M      V V V D ND 
Sbjct: 41   YKFGIKSATGGLFVAKTLDYESYD------RFFELTLNASDGMHTASTRVQVTVLDANDN 202

Query: 928  PPVFSK---RIYKGMVAPD-AVKGTP--ITTVYAEDADPPGMPASRVRYRVDDVQFPYPA 981
             P F     RI   +V  D +V   P  + TV A D D      + + Y +       P 
Sbjct: 203  APEFIDTPYRIENRIVEEDKSVTTRPKRLLTVLATDRDTDR--PNNISYTLQGYGTEPPN 376

Query: 982  SIFDVEEDSGRVVTRVNLNEEP---TTIFKLVVVAFDD-GEPVMSSSATVRILVLHPGEI 1037
              F ++  +G +     L+ +     + ++  VVA D+  +P     ATV +L   P +I
Sbjct: 377  QYFRIDPITGGLFVIKPLDRDGPHGRSNYQFTVVARDEPHQPWQFGYATVEVL---PADI 547

Query: 1038 ----PRFTQEEYRPPPVSELAARGTVVGVISAA----AINQSIVYSIV-----AGNEEDK 1084
                P F   + +   V E +  GT V  + A       N S+VY I+      G+++D 
Sbjct: 548  NDNKPTFDATKLKGS-VDEHSEPGTSVMFVLATDPDRGNNGSVVYDIIKNSVTVGSKQDY 724

Query: 1085 FGINNVTGVIYVN---SPLDYETRTSYVLRVQADSLEVVLANLRVPSKSNTAKVYIEIQD 1141
            F I+  +G+I  N     LD ET  S+ L V+A       ++   P  + TA + I + D
Sbjct: 725  FVIDRQSGLIKTNVDKRDLDRETIPSFTLEVRA-------SDEGKPPLNTTATITISLSD 883

Query: 1142 ENDHPPVFQKK 1152
             ND  PVF  K
Sbjct: 884  INDQKPVFDPK 916

 Score = 41.2 bits (95), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 50/169 (29%), Positives = 77/169 (45%), Gaps = 10/169 (5%)
 Frame = +2

Query: 1074 YSIVAGNEE-DKFGINNVTGVIYVNSPLDYETRTSYVLRVQADSLEVVLANLRVPSKSNT 1132
            Y IV GN    KFGI + TG ++V   LDYE+   +         E+ L N      + +
Sbjct: 11   YLIVDGNAPLYKFGIKSATGGLFVAKTLDYESYDRF--------FELTL-NASDGMHTAS 163

Query: 1133 AKVYIEIQDENDHPPVF-QKKFYIGG--VSEDARMFA---SVLRVKATDRDTGNYSAMAY 1186
             +V + + D ND+ P F    + I    V ED  +      +L V ATDRDT   + ++Y
Sbjct: 164  TRVQVTVLDANDNAPEFIDTPYRIENRIVEEDKSVTTRPKRLLTVLATDRDTDRPNNISY 343

Query: 1187 RLIIPPIKEGKEGFVVETYTG---LIKTAMLFHNMRRSYFKFQVIATDD 1232
             L     +   + F ++  TG   +IK         RS ++F V+A D+
Sbjct: 344  TLQGYGTEPPNQYFRIDPITGGLFVIKPLDRDGPHGRSNYQFTVVARDE 490

 Score = 35.8 bits (81), Expect = 0.18,   Method: Compositional matrix adjust.
 Identities = 33/113 (29%), Positives = 50/113 (44%), Gaps = 2/113 (1%)
 Frame = +2

Query: 89  WVLLDPVKQMLFLNSTGRVLDRDPPMNIHSIVVQVQCVNK--KVGTVIYHEVRIVVRDRN 146
           +  +DP+   LF+    + LDRD P    +    V   ++  +     Y  V ++  D N
Sbjct: 380 YFRIDPITGGLFVI---KPLDRDGPHGRSNYQFTVVARDEPHQPWQFGYATVEVLPADIN 550

Query: 147 DNSPTFKHESYYATVNELTPVGTTIFTGFSGDNGATDIDDGPNGQIEYVIQYN 199
           DN PTF       +V+E +  GT++         ATD D G NG + Y I  N
Sbjct: 551 DNKPTFDATKLKGSVDEHSEPGTSVMFVL-----ATDPDRGNNGSVVYDIIKN 694
>12703
          Length = 1529

 Score = 76.3 bits (186), Expect = 1e-13,   Method: Compositional matrix adjust.
 Identities = 54/165 (32%), Positives = 86/165 (52%), Gaps = 21/165 (12%)
 Frame = -1

Query: 100  FLNSTGRVLDRD-----PPMNIHSIVVQVQCV-NKKVGTVIYHEVRIVVRDRNDNSPTFK 153
            +L +  + LDRD     P  + +++  +V+C  N    T+ YH ++I + D NDN+P F 
Sbjct: 1442 YLLTMLKSLDRDGSLPTPNDDTNTLQYRVKCSPNNDADTLFYHILKIGISDVNDNAPQFS 1263

Query: 154  HESYYATVNELTPVGTTIFTGFSGDNGATDIDDGPNGQIEYVIQYNPEDPTSN------D 207
             +SY   +NELTP+G T++   +    ATD+D+G N Q+ + I     DP +N      D
Sbjct: 1262 ADSYAVQINELTPIGITVYNSIT----ATDLDNGNNKQVVWSI-----DPATNSLFKNQD 1110

Query: 208  TFEIPLMLTGNVVLRKRLNYEDK---------TRYYVIIQANDRA 243
             F +P      VVL ++L+YE           T Y + + A+DRA
Sbjct: 1109 VFIMPTNDNSFVVLNEKLDYEAMIEVMGSPTLTVYKMNVTASDRA 975

 Score = 32.3 bits (72), Expect = 2.0,   Method: Compositional matrix adjust.
 Identities = 24/82 (29%), Positives = 39/82 (47%), Gaps = 4/82 (4%)
 Frame = -3

Query: 782 LNREARDHYELVVVATDGAVHPRHS-TLTLYIKVLDIDDNSPVFTNSTYTVVVEE---NL 837
           L+ E R  Y   V+  +     R S T+TL + VLD++DN+P   ++ +   V E     
Sbjct: 249 LDYETRPSYIFDVIVRELDTEERFSSTVTLTVSVLDVNDNAPFIPSAIFNQFVPEGSYTS 70

Query: 838 PAGTSFLQIEAKDVDLGANVSY 859
             G   + + A DV+   N+ Y
Sbjct: 69  SVGQFLINVGANDVEDTTNLLY 4
>18971
          Length = 787

 Score = 59.3 bits (142), Expect(2) = 2e-13,   Method: Compositional matrix adjust.
 Identities = 46/137 (33%), Positives = 70/137 (51%), Gaps = 11/137 (8%)
 Frame = -2

Query: 804 RHSTLTLYIKVLDIDDNSPVFTNSTYTVVVEENLPAGTSFLQIEAKDVDLGAN--VSYRI 861
           + ST T+ + V+D++D SP F    Y V V+EN   GTS   + A+D+D   N  ++Y +
Sbjct: 459 KRSTATVILTVMDVNDISPSFKQDYYEVRVQENTAVGTSVGLVNAEDMDSNDNGRITYSL 280

Query: 862 --RSPEVKHL----FALHPFT---GELSLLRSLDYEAFPDQEASITFLVEAFDIYGTMPP 912
               P+  +     F +  F    G L+L R LD+E      +    LV A D       
Sbjct: 279 AWEHPQKMYFDPMDFHIPLFVSPEGTLTLERQLDHE----MTSEYNLLVLAVDGGDPART 112

Query: 913 GIATVTVIVKDMNDYPP 929
           G AT+T++V+D+ND PP
Sbjct: 111 GTATITLLVEDVNDNPP 61

 Score = 36.2 bits (82), Expect(2) = 2e-13,   Method: Compositional matrix adjust.
 Identities = 27/84 (32%), Positives = 36/84 (42%), Gaps = 2/84 (2%)
 Frame = -3

Query: 720 PVFDPYLPRNLSVVEEEANAFVGQVRATDPDAGINGQVHYSLGNFNNLFRIT--SNGSIY 777
           P FD  +     V   +    V +VRA DPD G NG+V YS+ +      +T   NG I 
Sbjct: 716 PRFDQDVYYETVVENNDVGVQVARVRARDPDVGDNGKVDYSISSNRGDVGVTMDRNGYII 537

Query: 778 TAVKLNREARDHYELVVVATDGAV 801
                + E        V ATD A+
Sbjct: 536 ATRSFDHEQNHQLSFEVFATDRAI 465

 Score = 47.4 bits (111), Expect(2) = 3e-10,   Method: Compositional matrix adjust.
 Identities = 37/127 (29%), Positives = 58/127 (45%), Gaps = 10/127 (7%)
 Frame = -2

Query: 915  ATVTVIVKDMNDYPPVFSKRIYKGMVAPDAVKGTPITTVYAEDADPPGMPASRVRYRV-- 972
            ATV + V D+ND  P F +  Y+  V  +   GT +  V AED D       R+ Y +  
Sbjct: 447  ATVILTVMDVNDISPSFKQDYYEVRVQENTAVGTSVGLVNAEDMD--SNDNGRITYSLAW 274

Query: 973  --------DDVQFPYPASIFDVEEDSGRVVTRVNLNEEPTTIFKLVVVAFDDGEPVMSSS 1024
                    D + F  P  +       G +     L+ E T+ + L+V+A D G+P  + +
Sbjct: 273  EHPQKMYFDPMDFHIPLFV----SPEGTLTLERQLDHEMTSEYNLLVLAVDGGDPARTGT 106

Query: 1025 ATVRILV 1031
            AT+ +LV
Sbjct: 105  ATITLLV 85

 Score = 37.4 bits (85), Expect(2) = 3e-10,   Method: Compositional matrix adjust.
 Identities = 30/96 (31%), Positives = 43/96 (44%), Gaps = 2/96 (2%)
 Frame = -3

Query: 812 IKVLDIDDNSPVFTNSTYTVVVEENLPAGTSFLQIEAKDVDLGAN--VSYRIRSPEVKHL 869
           + V+D +DN+P F    Y   V EN   G    ++ A+D D+G N  V Y I S     +
Sbjct: 746 VNVMDENDNAPRFDQDVYYETVVENNDVGVQVARVRARDPDVGDNGKVDYSISSNR-GDV 570

Query: 870 FALHPFTGELSLLRSLDYEAFPDQEASITFLVEAFD 905
                  G +   RS D+E    Q   ++F V A D
Sbjct: 569 GVTMDRNGYIIATRSFDHE----QNHQLSFEVFATD 474

 Score = 52.0 bits (123), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 38/111 (34%), Positives = 60/111 (54%), Gaps = 7/111 (6%)
 Frame = -2

Query: 138 VRIVVRDRNDNSPTFKHESYYATVNELTPVGTTIFTGFSGDNGATDIDDGPNGQIEYVIQ 197
           V + V D ND SP+FK + Y   V E T VGT++     G   A D+D   NG+I Y + 
Sbjct: 441 VILTVMDVNDISPSFKQDYYEVRVQENTAVGTSV-----GLVNAEDMDSNDNGRITYSLA 277

Query: 198 Y-NPE----DPTSNDTFEIPLMLT--GNVVLRKRLNYEDKTRYYVIIQAND 241
           + +P+    DP     F IPL ++  G + L ++L++E  + Y +++ A D
Sbjct: 276 WEHPQKMYFDPMD---FHIPLFVSPEGTLTLERQLDHEMTSEYNLLVLAVD 133

 Score = 45.1 bits (105), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 29/94 (30%), Positives = 46/94 (48%), Gaps = 12/94 (12%)
 Frame = -2

Query: 741 VGQVRATDPDAGINGQVHYSLG------------NFNNLFRITSNGSIYTAVKLNREARD 788
           VG V A D D+  NG++ YSL             +F+    ++  G++    +L+ E   
Sbjct: 342 VGLVNAEDMDSNDNGRITYSLAWEHPQKMYFDPMDFHIPLFVSPEGTLTLERQLDHEMTS 163

Query: 789 HYELVVVATDGAVHPRHSTLTLYIKVLDIDDNSP 822
            Y L+V+A DG    R  T T+ + V D++DN P
Sbjct: 162 EYNLLVLAVDGGDPARTGTATITLLVEDVNDNPP 61

 Score = 41.2 bits (95), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 46/158 (29%), Positives = 70/158 (44%), Gaps = 10/158 (6%)
 Frame = -2

Query: 500 VNIRVMDANDNTPTFPEISYDVYVYTDMSPGDSVIQLTAVDADEGSNGEISYEI------ 553
           V + VMD ND +P+F +  Y+V V  + + G SV  + A D D   NG I+Y +      
Sbjct: 441 VILTVMDVNDISPSFKQDYYEVRVQENTAVGTSVGLVNAEDMDSNDNGRITYSLAWEHPQ 262

Query: 554 -LVGGKGDFVIN---KTTGLVSIAPGVELIVGQTYALTVQASDNAPPAERRHSICTVYIE 609
            +     DF I       G +++   ++  +   Y L V A D   PA    +  T+ +E
Sbjct: 261 KMYFDPMDFHIPLFVSPEGTLTLERQLDHEMTSEYNLLVLAVDGGDPARTGTATITLLVE 82

Query: 610 VLPPNNQSPPRFPQLMYSLEVSEAMRIGAILLNLQATD 647
            +   N +PP+       + V E   I AI L   ATD
Sbjct: 81  DV---NDNPPQ-------IVVPEPHNISAIAL---ATD 7

 Score = 40.4 bits (93), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 40/145 (27%), Positives = 68/145 (46%), Gaps = 14/145 (9%)
 Frame = -2

Query: 1017 GEPVMSSSATVRILVLHPGEI-PRFTQEEYRPPPVSELAARGTVVGVISAAAI----NQS 1071
            G+P   S+ATV + V+   +I P F Q+ Y    V E  A GT VG+++A  +    N  
Sbjct: 471  GDPKKRSTATVILTVMDVNDISPSFKQDYYE-VRVQENTAVGTSVGLVNAEDMDSNDNGR 295

Query: 1072 IVYSIVAGNEEDKFG---------INNVTGVIYVNSPLDYETRTSYVLRVQADSLEVVLA 1122
            I YS+   + +  +            +  G + +   LD+E  + Y L V A        
Sbjct: 294  ITYSLAWEHPQKMYFDPMDFHIPLFVSPEGTLTLERQLDHEMTSEYNLLVLA-------V 136

Query: 1123 NLRVPSKSNTAKVYIEIQDENDHPP 1147
            +   P+++ TA + + ++D ND+PP
Sbjct: 135  DGGDPARTGTATITLLVEDVNDNPP 61

 Score = 40.0 bits (92), Expect = 0.010,   Method: Compositional matrix adjust.
 Identities = 32/109 (29%), Positives = 48/109 (44%)
 Frame = -3

Query: 142 VRDRNDNSPTFKHESYYATVNELTPVGTTIFTGFSGDNGATDIDDGPNGQIEYVIQYNPE 201
           V D NDN+P F  + YY TV E   VG  +         A D D G NG+++Y I  N  
Sbjct: 740 VMDENDNAPRFDQDVYYETVVENNDVGVQVARV-----RARDPDVGDNGKVDYSISSNRG 576

Query: 202 DPTSNDTFEIPLMLTGNVVLRKRLNYEDKTRYYVIIQANDRAQNLNERR 250
           D        + +   G ++  +  ++E   +    + A DRA    +RR
Sbjct: 575 D------VGVTMDRNGYIIATRSFDHEQNHQLSFEVFATDRAILRKDRR 447

 Score = 35.8 bits (81), Expect = 0.18,   Method: Compositional matrix adjust.
 Identities = 20/52 (38%), Positives = 27/52 (51%)
 Frame = -3

Query: 502 IRVMDANDNTPTFPEISYDVYVYTDMSPGDSVIQLTAVDADEGSNGEISYEI 553
           + VMD NDN P F +  Y   V  +   G  V ++ A D D G NG++ Y I
Sbjct: 746 VNVMDENDNAPRFDQDVYYETVVENNDVGVQVARVRARDPDVGDNGKVDYSI 591
>29160
          Length = 1022

 Score = 74.7 bits (182), Expect = 3e-13,   Method: Compositional matrix adjust.
 Identities = 66/226 (29%), Positives = 101/226 (44%), Gaps = 17/226 (7%)
 Frame = -2

Query: 764  FNNLFRITSNGSI--YTAVKLNREARDHYELVVVATDGAVHPRH-STLTLYIKVLDIDDN 820
            F  +  I + GSI  Y  V   + +R  + L V+A D   +PRH +T  + I V D +DN
Sbjct: 1009 FFQVITIDNMGSILVYNEVDYEQASRQFFNLTVIAEDP--NPRHTATAYVAIXVRDFNDN 836

Query: 821  SPVFTNSTYTVVVEENLPAGTSFLQIEAKDVDLGANVSYRI---RSPEVKHLFALHPFTG 877
            +P       TV + E+ PAG       A D+D G N  +     R  + +  F++HP TG
Sbjct: 835  APAIKPQVITVRIFEDEPAGFHVATFNATDMDSGDNAKFEFSIDRHTDPRRHFSIHPETG 656

Query: 878  ELSLLRSLDYEAFPDQEASITFLVEAFDIYGTMPPGIATVTVIVKDMNDYPPVFSKRIYK 937
             ++L R LD E    Q+  +   + A D       G  T+TV VKD+ND  P F +    
Sbjct: 655  RVTLRRPLDRET---QDHHV-ITIRAIDKGDPPMTGYGTLTVFVKDINDNFPQFLENYQP 488

Query: 938  GMVAPDAVKGTPITTVYAEDAD-----------PPGMPASRVRYRV 972
             ++  +      +  ++A+D D           PP +P      RV
Sbjct: 487  QVLERENNFPAVLQQIFAKDPDASPFGPPLALLPPCVPTGPCTVRV 350

 Score = 52.0 bits (123), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 55/182 (30%), Positives = 84/182 (46%), Gaps = 8/182 (4%)
 Frame = -2

Query: 582 QTYALTVQASDNAPPAERRHSICTVYIEVLPPNNQSPPRFPQLMYSLEVSEAMRIGAILL 641
           Q + LTV A D   P  R  +   V I V   N+ +P   PQ++ ++ + E    G  + 
Sbjct: 931 QFFNLTVIAED---PNPRHTATAYVAIXVRDFNDNAPAIKPQVI-TVRIFEDEPAGFHVA 764

Query: 642 NLQATDRE-GDPITYAI---ENGDPQRVFNLSETTGILSLGKALDRESTDRYILIVTASD 697
              ATD + GD   +      + DP+R F++   TG ++L + LDRE+ D +++ + A D
Sbjct: 763 TFNATDMDSGDNAKFEFSIDRHTDPRRHFSIHPETGRVTLRRPLDRETQDHHVITIRAID 584

Query: 698 -GRPDGTSXXXXXXXXXXXXXXXPVF-DPYLPRNLSVVEEEAN--AFVGQVRATDPDAGI 753
            G P  T                P F + Y P+   V+E E N  A + Q+ A DPDA  
Sbjct: 583 KGDPPMTGYGTLTVFVKDINDNFPQFLENYQPQ---VLERENNFPAVLQQIFAKDPDASP 413

Query: 754 NG 755
            G
Sbjct: 412 FG 407

 Score = 51.6 bits (122), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 55/192 (28%), Positives = 80/192 (41%), Gaps = 9/192 (4%)
 Frame = -2

Query: 670 ETTGILSLGKALDRESTDR--YILIVTASDGRPDGTSXXXXXXXXXXXXXXXPVFDPYLP 727
           +  G + +   +D E   R  + L V A D  P  T+               P   P + 
Sbjct: 988 DNMGSILVYNEVDYEQASRQFFNLTVIAEDPNPRHTATAYVAIXVRDFNDNAPAIKPQV- 812

Query: 728 RNLSVVEEEANAF-VGQVRATDPDAGINGQVHYSLGNFNNLFRITS----NGSIYTAVKL 782
             + + E+E   F V    ATD D+G N +  +S+    +  R  S     G +     L
Sbjct: 811 ITVRIFEDEPAGFHVATFNATDMDSGDNAKFEFSIDRHTDPRRHFSIHPETGRVTLRRPL 632

Query: 783 NREARDHYELVVVATDGAVHPRHSTLTLYIKVLDIDDNSPVFTNSTYTVVVEE--NLPAG 840
           +RE +DH+ + + A D    P     TL + V DI+DN P F  +    V+E   N PA 
Sbjct: 631 DRETQDHHVITIRAIDKGDPPMTGYGTLTVFVKDINDNFPQFLENYQPQVLERENNFPA- 455

Query: 841 TSFLQIEAKDVD 852
               QI AKD D
Sbjct: 454 -VLQQIFAKDPD 422

 Score = 43.9 bits (102), Expect = 6e-04,   Method: Compositional matrix adjust.
 Identities = 36/106 (33%), Positives = 52/106 (49%)
 Frame = -2

Query: 138 VRIVVRDRNDNSPTFKHESYYATVNELTPVGTTIFTGFSGDNGATDIDDGPNGQIEYVIQ 197
           V I VRD NDN+P  K +     + E  P G  + T       ATD+D G N + E+ I 
Sbjct: 868 VAIXVRDFNDNAPAIKPQVITVRIFEDEPAGFHVATF-----NATDMDSGDNAKFEFSID 704

Query: 198 YNPEDPTSNDTFEIPLMLTGNVVLRKRLNYEDKTRYYVIIQANDRA 243
            +  DP  +  F I    TG V LR+ L+ E +  + + I+A D+ 
Sbjct: 703 RH-TDPRRH--FSI-HPETGRVTLRRPLDRETQDHHVITIRAIDKG 578

 Score = 43.5 bits (101), Expect = 8e-04,   Method: Compositional matrix adjust.
 Identities = 42/172 (24%), Positives = 73/172 (42%), Gaps = 1/172 (0%)
 Frame = -2

Query: 877  GELSLLRSLDYEAFPDQEASITFLVEAFDIYGTMPPGIATVTVIVKDMNDYPPVFSKRIY 936
            G + +   +DYE    Q  ++T + E  +   T     A V + V+D ND  P    ++ 
Sbjct: 979  GSILVYNEVDYEQASRQFFNLTVIAEDPNPRHT---ATAYVAIXVRDFNDNAPAIKPQVI 809

Query: 937  KGMVAPDAVKGTPITTVYAEDADPPGMPASRVRYRVDDVQFPYPASIFDVEEDSGRVVTR 996
               +  D   G  + T  A D D      ++  + +D  +   P   F +  ++GRV  R
Sbjct: 808  TVRIFEDEPAGFHVATFNATDMD--SGDNAKFEFSID--RHTDPRRHFSIHPETGRVTLR 641

Query: 997  VNLNEEPTTIFKLVVVAFDDGEPVMSSSATVRILVLHPGE-IPRFTQEEYRP 1047
              L+ E      + + A D G+P M+   T+ + V    +  P+F  E Y+P
Sbjct: 640  RPLDRETQDHHVITIRAIDKGDPPMTGYGTLTVFVKDINDNFPQFL-ENYQP 488

 Score = 33.1 bits (74), Expect = 1.0,   Method: Compositional matrix adjust.
 Identities = 27/102 (26%), Positives = 46/102 (45%)
 Frame = -2

Query: 1087 INNVTGVIYVNSPLDYETRTSYVLRVQADSLEVVLANLRVPSKSNTAKVYIEIQDENDHP 1146
            I+N+ G I V + +DYE  +     +       V+A    P  + TA V I ++D ND+ 
Sbjct: 991  IDNM-GSILVYNEVDYEQASRQFFNL------TVIAEDPNPRHTATAYVAIXVRDFNDNA 833

Query: 1147 PVFQKKFYIGGVSEDARMFASVLRVKATDRDTGNYSAMAYRL 1188
            P  + +     + ED      V    ATD D+G+ +   + +
Sbjct: 832  PAIKPQVITVRIFEDEPAGFHVATFNATDMDSGDNAKFEFSI 707
>19334
          Length = 923

 Score = 47.8 bits (112), Expect(2) = 5e-13,   Method: Compositional matrix adjust.
 Identities = 43/160 (26%), Positives = 73/160 (45%), Gaps = 5/160 (3%)
 Frame = +3

Query: 892  DQEASITFLVEAFDIYGTMPPGIATVTVIVKDMNDYPPVFSKRIYKGMVAPDAVKGTPIT 951
            +Q+   T +V+  D+          V V ++D+ND  P+F K+ +K +V+ D   G  + 
Sbjct: 93   EQQDQYTVVVQVVDLNPEPHTAHVVVMVTIEDVNDNTPMFVKQPFKTIVSTDTEHGETVK 272

Query: 952  TVYAEDADPPGMPASRVRYRV-----DDVQFPYPASIFDVEEDSGRVVTRVNLNEEPTTI 1006
             V A D D        +RY +     D+V+       F + + +G +V R    ++  T 
Sbjct: 273  KVTAADGDLGD--NGEIRYFLPMHLTDNVK-----DAFAINQYTGDIVVRRLTEDDRDTT 431

Query: 1007 FKLVVVAFDDGEPVMSSSATVRILVLHPGEIPRFTQEEYR 1046
            F L V A D G P +S++  V I V+     P F  ++ R
Sbjct: 432  FLLTVEAVDQGSPPLSATVEVPIHVVDSSS-PVFESQQLR 548

 Score = 46.2 bits (108), Expect(2) = 5e-13,   Method: Compositional matrix adjust.
 Identities = 32/97 (32%), Positives = 51/97 (52%), Gaps = 2/97 (2%)
 Frame = +2

Query: 1085 FGINNVTGVIYVNSPLDYETRTSYVLRVQADSLEVVLANLRVPSKSNTAKVYIEI--QDE 1142
            F I+  TG++ V   LD E++  Y L ++A  +          S ++ A +++ +  QD 
Sbjct: 662  FAIDFNTGLVLVAGQLDRESQERYQLVLRASDV----------SSASYADMHLTVILQDV 811

Query: 1143 NDHPPVFQKKFYIGGVSEDARMFASVLRVKATDRDTG 1179
            ND+ PVF+   Y   VSE AR+  S+L+V A D D  
Sbjct: 812  NDNSPVFESLRYTHTVSEVARVGTSILQVAARDSDNA 922

 Score = 71.2 bits (173), Expect = 4e-12,   Method: Compositional matrix adjust.
 Identities = 48/130 (36%), Positives = 66/130 (50%), Gaps = 6/130 (4%)
 Frame = +3

Query: 473 PVDREEQQTYTFLITAFDGVQE--SEPVVVNIRVMDANDNTPTFPEISYDVYVYTDMSPG 530
           P DRE+Q  YT ++   D   E  +  VVV + + D NDNTP F +  +   V TD   G
Sbjct: 81  PFDREQQDQYTVVVQVVDLNPEPHTAHVVVMVTIEDVNDNTPMFVKQPFKTIVSTDTEHG 260

Query: 531 DSVIQLTAVDADEGSNGEISY----EILVGGKGDFVINKTTGLVSIAPGVELIVGQTYAL 586
           ++V ++TA D D G NGEI Y     +    K  F IN+ TG + +    E     T+ L
Sbjct: 261 ETVKKVTAADGDLGDNGEIRYFLPMHLTDNVKDAFAINQYTGDIVVRRLTEDDRDTTFLL 440

Query: 587 TVQASDNAPP 596
           TV+A D   P
Sbjct: 441 TVEAVDQGSP 470

 Score = 62.4 bits (150), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 46/158 (29%), Positives = 80/158 (50%), Gaps = 5/158 (3%)
 Frame = +3

Query: 782 LNREARDHYELVVVATDGAVHPRHSTLTLYIKVLDIDDNSPVFTNSTYTVVVEENLPAGT 841
            +RE +D Y +VV   D    P  + + + + + D++DN+P+F    +  +V  +   G 
Sbjct: 84  FDREQQDQYTVVVQVVDLNPEPHTAHVVVMVTIEDVNDNTPMFVKQPFKTIVSTDTEHGE 263

Query: 842 SFLQIEAKDVDLGANVSYRIRSP-----EVKHLFALHPFTGELSLLRSLDYEAFPDQEAS 896
           +  ++ A D DLG N   R   P      VK  FA++ +TG++ ++R L  +   D++ +
Sbjct: 264 TVKKVTAADGDLGDNGEIRYFLPMHLTDNVKDAFAINQYTGDI-VVRRLTED---DRDTT 431

Query: 897 ITFLVEAFDIYGTMPPGIATVTVIVKDMNDYPPVFSKR 934
               VEA D  G+ PP  ATV V +  ++   PVF  +
Sbjct: 432 FLLTVEAVD-QGS-PPLSATVEVPIHVVDSSSPVFESQ 539

 Score = 56.6 bits (135), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 44/152 (28%), Positives = 67/152 (44%)
 Frame = +3

Query: 1098 SPLDYETRTSYVLRVQADSLEVVLANLRVPSKSNTAKVYIEIQDENDHPPVFQKKFYIGG 1157
            SP D E +  Y + VQ       + +L     +    V + I+D ND+ P+F K+ +   
Sbjct: 78   SPFDREQQDQYTVVVQ-------VVDLNPEPHTAHVVVMVTIEDVNDNTPMFVKQPFKTI 236

Query: 1158 VSEDARMFASVLRVKATDRDTGNYSAMAYRLIIPPIKEGKEGFVVETYTGLIKTAMLFHN 1217
            VS D     +V +V A D D G+   + Y L +      K+ F +  YTG I    L  +
Sbjct: 237  VSTDTEHGETVKKVTAADGDLGDNGEIRYFLPMHLTDNVKDAFAINQYTGDIVVRRLTED 416

Query: 1218 MRRSYFKFQVIATDDYGKGLSGKADVLVSVVN 1249
             R + F   V A D     LS   +V + VV+
Sbjct: 417  DRDTTFLLTVEAVDQGSPPLSATVEVPIHVVD 512

 Score = 55.1 bits (131), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 33/93 (35%), Positives = 56/93 (60%)
 Frame = +2

Query: 760 SLGNFNNLFRITSNGSIYTAVKLNREARDHYELVVVATDGAVHPRHSTLTLYIKVLDIDD 819
           ++G F   F   + G +  A +L+RE+++ Y+LV+ A+D +    ++ + L + + D++D
Sbjct: 650 AMGTFAIDF---NTGLVLVAGQLDRESQERYQLVLRASDVS-SASYADMHLTVILQDVND 817

Query: 820 NSPVFTNSTYTVVVEENLPAGTSFLQIEAKDVD 852
           NSPVF +  YT  V E    GTS LQ+ A+D D
Sbjct: 818 NSPVFESLRYTHTVSEVARVGTSILQVAARDSD 916

 Score = 42.0 bits (97), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 41/151 (27%), Positives = 62/151 (41%), Gaps = 7/151 (4%)
 Frame = +3

Query: 681 LDRESTDRYILIVTASDGRPD-GTSXXXXXXXXXXXXXXXPVFDPYLPRNLSVVEEEANA 739
            DRE  D+Y ++V   D  P+  T+               P+F     + +   + E   
Sbjct: 84  FDREQQDQYTVVVQVVDLNPEPHTAHVVVMVTIEDVNDNTPMFVKQPFKTIVSTDTEHGE 263

Query: 740 FVGQVRATDPDAGINGQVHYSL-----GNFNNLFRITSNGSIYTAVKLNREARD-HYELV 793
            V +V A D D G NG++ Y L      N  + F I          +L  + RD  + L 
Sbjct: 264 TVKKVTAADGDLGDNGEIRYFLPMHLTDNVKDAFAINQYTGDIVVRRLTEDDRDTTFLLT 443

Query: 794 VVATDGAVHPRHSTLTLYIKVLDIDDNSPVF 824
           V A D    P  +T+ + I V  +D +SPVF
Sbjct: 444 VEAVDQGSPPLSATVEVPIHV--VDSSSPVF 530

 Score = 41.6 bits (96), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 28/96 (29%), Positives = 47/96 (48%)
 Frame = +2

Query: 554 LVGGKGDFVINKTTGLVSIAPGVELIVGQTYALTVQASDNAPPAERRHSICTVYIEVLPP 613
           +V   G F I+  TGLV +A  ++    + Y L ++ASD +  +     +  +  +V   
Sbjct: 641 MVIAMGTFAIDFNTGLVLVAGQLDRESQERYQLVLRASDVSSASYADMHLTVILQDV--- 811

Query: 614 NNQSPPRFPQLMYSLEVSEAMRIGAILLNLQATDRE 649
            N + P F  L Y+  VSE  R+G  +L + A D +
Sbjct: 812 -NDNSPVFESLRYTHTVSEVARVGTSILQVAARDSD 916

 Score = 36.6 bits (83), Expect = 0.090,   Method: Compositional matrix adjust.
 Identities = 22/72 (30%), Positives = 36/72 (50%), Gaps = 1/72 (1%)
 Frame = +2

Query: 474 VDREEQQTYTFLITAFDGVQES-EPVVVNIRVMDANDNTPTFPEISYDVYVYTDMSPGDS 532
           +DRE Q+ Y  ++ A D    S   + + + + D NDN+P F  + Y   V      G S
Sbjct: 707 LDRESQERYQLVLRASDVSSASYADMHLTVILQDVNDNSPVFESLRYTHTVSEVARVGTS 886

Query: 533 VIQLTAVDADEG 544
           ++Q+ A D+D  
Sbjct: 887 ILQVAARDSDNA 922

 Score = 35.8 bits (81), Expect = 0.16,   Method: Compositional matrix adjust.
 Identities = 15/33 (45%), Positives = 23/33 (69%)
 Frame = +2

Query: 140 IVVRDRNDNSPTFKHESYYATVNELTPVGTTIF 172
           ++++D NDNSP F+   Y  TV+E+  VGT+I 
Sbjct: 794 VILQDVNDNSPVFESLRYTHTVSEVARVGTSIL 892

 Score = 35.8 bits (81), Expect = 0.18,   Method: Compositional matrix adjust.
 Identities = 19/43 (44%), Positives = 25/43 (58%)
 Frame = +2

Query: 917 VTVIVKDMNDYPPVFSKRIYKGMVAPDAVKGTPITTVYAEDAD 959
           +TVI++D+ND  PVF    Y   V+  A  GT I  V A D+D
Sbjct: 788 LTVILQDVNDNSPVFESLRYTHTVSEVARVGTSILQVAARDSD 916

 Score = 30.8 bits (68), Expect = 5.7,   Method: Compositional matrix adjust.
 Identities = 14/32 (43%), Positives = 21/32 (65%)
 Frame = +2

Query: 666 FNLSETTGILSLGKALDRESTDRYILIVTASD 697
           F +   TG++ +   LDRES +RY L++ ASD
Sbjct: 662 FAIDFNTGLVLVAGQLDRESQERYQLVLRASD 757
>35151
          Length = 844

 Score = 73.6 bits (179), Expect = 7e-13,   Method: Compositional matrix adjust.
 Identities = 80/278 (28%), Positives = 127/278 (45%), Gaps = 19/278 (6%)
 Frame = +2

Query: 907  YGTMPPGIATVTVIVKDMNDYPPVFSKRIYKGMVAPDAVKGTPITTV--YAEDADPPGMP 964
            +GT     A VT+ V D+ND  P FS+  Y   +  + +KG P+T +      +D     
Sbjct: 56   FGTTTAS-AIVTISVTDVNDNVPEFSQTNYHAQIQENMLKGVPLTFLGGVMRVSDKDQGT 232

Query: 965  ASRVRYRVDDVQFPY------PASIFDVEEDSGRVVTRVNLNE------EPTTIFKLVVV 1012
             S     V+    PY      P  ++        V+ RVN +E      E   IF++V  
Sbjct: 233  NSHFALTVEKNGQPYHDFTTLPEEVY----TESTVLLRVNNSESLDYEAEKEIIFQIVAR 400

Query: 1013 AFDDGEPVMSSSATVRILVLHPGE-IPRFTQEEYRPPPVSELAARGTVVGVISAAAINQ- 1070
              D  E   SS+ATV + +L   +  P FT  +Y    V+E A+ G  +G I A+  +  
Sbjct: 401  EVDTAEQ-RSSTATVTLNILDMNDNAPNFTHSQY-LFTVAEDASVGQSIGDIFASDDDTG 574

Query: 1071 ---SIVYSIVAGNEEDKFGINNVTGVIYVNSPLDYETRTSYVLRVQADSLEVVLANLRVP 1127
               S+ YSI   N    F ++++ G +YVN+ LD ET + Y L  +A    +     R P
Sbjct: 575  SYGSVRYSIRGENRH--FRVDSLNGTMYVNNALDRETTSRYFLSAEA----IDGGGTRAP 736

Query: 1128 SKSNTAKVYIEIQDENDHPPVFQKKFYIGGVSEDARMF 1165
            +     ++ I + D ND+ P+F++  Y G + E +  F
Sbjct: 737  T-----EIEIVVTDVNDNAPLFRRSDYEGVIREKSSTF 835

 Score = 70.5 bits (171), Expect = 7e-12,   Method: Compositional matrix adjust.
 Identities = 68/225 (30%), Positives = 104/225 (46%), Gaps = 26/225 (11%)
 Frame = +2

Query: 742 GQVRATDPDAGINGQVHYSLGNFNNLFRITSNGS-----------IYTAVKL-----NRE 785
           G +R +D D G N   H++L        +  NG            +YT   +     N E
Sbjct: 197 GVMRVSDKDQGTNS--HFAL-------TVEKNGQPYHDFTTLPEEVYTESTVLLRVNNSE 349

Query: 786 ARDH-------YELVVVATDGAVHPRHSTLTLYIKVLDIDDNSPVFTNSTYTVVVEENLP 838
           + D+       +++V    D A   R ST T+ + +LD++DN+P FT+S Y   V E+  
Sbjct: 350 SLDYEAEKEIIFQIVAREVDTA-EQRSSTATVTLNILDMNDNAPNFTHSQYLFTVAEDAS 526

Query: 839 AGTSFLQIEAKDVDLGA--NVSYRIRSPEVKHLFALHPFTGELSLLRSLDYEAFPDQEAS 896
            G S   I A D D G+  +V Y IR  E +H F +    G + +  +LD E       S
Sbjct: 527 VGQSIGDIFASDDDTGSYGSVRYSIRG-ENRH-FRVDSLNGTMYVNNALDRET-----TS 685

Query: 897 ITFL-VEAFDIYGTMPPGIATVTVIVKDMNDYPPVFSKRIYKGMV 940
             FL  EA D  GT  P    + ++V D+ND  P+F +  Y+G++
Sbjct: 686 RYFLSAEAIDGGGTRAP--TEIEIVVTDVNDNAPLFRRSDYEGVI 814

 Score = 67.0 bits (162), Expect = 6e-11,   Method: Compositional matrix adjust.
 Identities = 66/222 (29%), Positives = 98/222 (44%), Gaps = 16/222 (7%)
 Frame = +2

Query: 812  IKVLDIDDNSPVFTNSTYTVVVEENLPAGT--SFLQ--IEAKDVDLGANVSYRI---RSP 864
            I V D++DN P F+ + Y   ++EN+  G   +FL   +   D D G N  + +   ++ 
Sbjct: 89   ISVTDVNDNVPEFSQTNYHAQIQENMLKGVPLTFLGGVMRVSDKDQGTNSHFALTVEKNG 268

Query: 865  EVKHLFALHP---FTGELSLLR-----SLDYEAFPDQEASITFLVEAFDI-YGTMPPGIA 915
            +  H F   P   +T    LLR     SLDYEA    E  I F + A ++         A
Sbjct: 269  QPYHDFTTLPEEVYTESTVLLRVNNSESLDYEA----EKEIIFQIVAREVDTAEQRSSTA 436

Query: 916  TVTVIVKDMNDYPPVFSKRIYKGMVAPDAVKGTPITTVYAEDADPPGMPASRVRYRVDDV 975
            TVT+ + DMND  P F+   Y   VA DA  G  I  ++A D D     + R   R ++ 
Sbjct: 437  TVTLNILDMNDNAPNFTHSQYLFTVAEDASVGQSIGDIFASDDDTGSYGSVRYSIRGENR 616

Query: 976  QFPYPASIFDVEEDSGRVVTRVNLNEEPTTIFKLVVVAFDDG 1017
             F        V+  +G +     L+ E T+ + L   A D G
Sbjct: 617  HFR-------VDSLNGTMYVNNALDRETTSRYFLSAEAIDGG 721

 Score = 64.7 bits (156), Expect = 4e-10,   Method: Compositional matrix adjust.
 Identities = 78/277 (28%), Positives = 117/277 (42%), Gaps = 25/277 (9%)
 Frame = +2

Query: 584 YALTVQASDNAPPAERRHSICT----VYIEVLPPNNQSPPRFPQLMYSLEVSEAMRIGAI 639
           YA+ VQA++   P  +     T    V I V   N+ + P F Q  Y  ++ E M  G  
Sbjct: 5   YAMWVQATEIDVPGRQNFGTTTASAIVTISVTDVND-NVPEFSQTNYHAQIQENMLKGVP 181

Query: 640 LLNLQATDR-----EGDPITYAI---ENGDPQRVFN------LSETTGILSLG--KALDR 683
           L  L    R     +G    +A+   +NG P   F        +E+T +L +   ++LD 
Sbjct: 182 LTFLGGVMRVSDKDQGTNSHFALTVEKNGQPYHDFTTLPEEVYTESTVLLRVNNSESLDY 361

Query: 684 ESTDRYILIVTAS--DGRPDGTSXXXXXXXXXXXXXXXPVFDPYLPRNLSVVEEEANA-- 739
           E+    I  + A   D     +S               P F     + L  V E+A+   
Sbjct: 362 EAEKEIIFQIVAREVDTAEQRSSTATVTLNILDMNDNAPNFTH--SQYLFTVAEDASVGQ 535

Query: 740 FVGQVRATDPDAGINGQVHYSLGNFNNLFRITS-NGSIYTAVKLNREARDHYELVVVATD 798
            +G + A+D D G  G V YS+   N  FR+ S NG++Y    L+RE    Y L   A D
Sbjct: 536 SIGDIFASDDDTGSYGSVRYSIRGENRHFRVDSLNGTMYVNNALDRETTSRYFLSAEAID 715

Query: 799 GAVHPRHSTLTLYIKVLDIDDNSPVFTNSTYTVVVEE 835
           G      +   + I V D++DN+P+F  S Y  V+ E
Sbjct: 716 GG--GTRAPTEIEIVVTDVNDNAPLFRRSDYEGVIRE 820

 Score = 49.7 bits (117), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 58/221 (26%), Positives = 90/221 (40%), Gaps = 10/221 (4%)
 Frame = +2

Query: 382 AFASLHIEILDENNQSPYFTMPSYQGYILESAPVGATISESLNLTTPLRIVALDKDIEDT 441
           A A + I + D N+  P F+  +Y   I E+   G  ++    L   +R+   DKD    
Sbjct: 71  ASAIVTISVTDVNDNVPEFSQTNYHAQIQENMLKGVPLTF---LGGVMRVS--DKDQGTN 235

Query: 442 KDPELHLFLNDY-TSVFTVTPTGITRYLTLL------QPVDREEQQTYTFLITAFD---G 491
               L +  N      FT  P  +    T+L      + +D E ++   F I A +    
Sbjct: 236 SHFALTVEKNGQPYHDFTTLPEEVYTESTVLLRVNNSESLDYEAEKEIIFQIVAREVDTA 415

Query: 492 VQESEPVVVNIRVMDANDNTPTFPEISYDVYVYTDMSPGDSVIQLTAVDADEGSNGEISY 551
            Q S    V + ++D NDN P F    Y   V  D S G S+  + A D D GS G + Y
Sbjct: 416 EQRSSTATVTLNILDMNDNAPNFTHSQYLFTVAEDASVGQSIGDIFASDDDTGSYGSVRY 595

Query: 552 EILVGGKGDFVINKTTGLVSIAPGVELIVGQTYALTVQASD 592
            I  G    F ++   G + +   ++      Y L+ +A D
Sbjct: 596 SIR-GENRHFRVDSLNGTMYVNNALDRETTSRYFLSAEAID 715

 Score = 48.9 bits (115), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 39/150 (26%), Positives = 67/150 (44%)
 Frame = +2

Query: 1100 LDYETRTSYVLRVQADSLEVVLANLRVPSKSNTAKVYIEIQDENDHPPVFQKKFYIGGVS 1159
            LDYE     + ++ A  ++          +S+TA V + I D ND+ P F    Y+  V+
Sbjct: 353  LDYEAEKEIIFQIVAREVDTA------EQRSSTATVTLNILDMNDNAPNFTHSQYLFTVA 514

Query: 1160 EDARMFASVLRVKATDRDTGNYSAMAYRLIIPPIKEGKEGFVVETYTGLIKTAMLFHNMR 1219
            EDA +  S+  + A+D DTG+Y ++ Y      I+     F V++  G +          
Sbjct: 515  EDASVGQSIGDIFASDDDTGSYGSVRY-----SIRGENRHFRVDSLNGTMYVNNALDRET 679

Query: 1220 RSYFKFQVIATDDYGKGLSGKADVLVSVVN 1249
             S +     A D  G     + +++V+ VN
Sbjct: 680  TSRYFLSAEAIDGGGTRAPTEIEIVVTDVN 769

 Score = 46.2 bits (108), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 34/104 (32%), Positives = 49/104 (47%)
 Frame = +2

Query: 138 VRIVVRDRNDNSPTFKHESYYATVNELTPVGTTIFTGFSGDNGATDIDDGPNGQIEYVIQ 197
           V + + D NDN+P F H  Y  TV E   VG +I     GD  A+D D G  G + Y I+
Sbjct: 440 VTLNILDMNDNAPNFTHSQYLFTVAEDASVGQSI-----GDIFASDDDTGSYGSVRYSIR 604

Query: 198 YNPEDPTSNDTFEIPLMLTGNVVLRKRLNYEDKTRYYVIIQAND 241
                   N  F +   L G + +   L+ E  +RY++  +A D
Sbjct: 605 ------GENRHFRVD-SLNGTMYVNNALDRETTSRYFLSAEAID 715

 Score = 45.8 bits (107), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 41/152 (26%), Positives = 58/152 (38%)
 Frame = +2

Query: 369 VIKAEQDNGHPLPAFASLHIEILDENNQSPYFTMPSYQGYILESAPVGATISESLNLTTP 428
           ++  E D      + A++ + ILD N+ +P FT   Y   + E A VG +I +       
Sbjct: 389 IVAREVDTAEQRSSTATVTLNILDMNDNAPNFTHSQYLFTVAEDASVGQSIGD------- 547

Query: 429 LRIVALDKDIEDTKDPELHLFLNDYTSVFTVTPTGITRYLTLLQPVDREEQQTYTFLITA 488
             I A D D        +   +      F V     T Y+     +DRE    Y     A
Sbjct: 548 --IFASDDDTGSYG--SVRYSIRGENRHFRVDSLNGTMYVN--NALDRETTSRYFLSAEA 709

Query: 489 FDGVQESEPVVVNIRVMDANDNTPTFPEISYD 520
            DG     P  + I V D NDN P F    Y+
Sbjct: 710 IDGGGTRAPTEIEIVVTDVNDNAPLFRRSDYE 805
>14946
          Length = 1599

 Score = 72.8 bits (177), Expect = 1e-12,   Method: Compositional matrix adjust.
 Identities = 114/430 (26%), Positives = 179/430 (41%), Gaps = 19/430 (4%)
 Frame = -3

Query: 829  YTVVVEENLPAGTSFLQIEAKDVDLGAN---VSYRIR-SPEVKHLFALHPFTGELSLLRS 884
            Y+V V E+   G  FLQ+ A D D  A    V+Y +  + +    F +   +G+LS+L+ 
Sbjct: 1570 YSVGVSEDRVVGDPFLQVTALDADFTAPNNLVTYTLAGNSKALEYFQVGSSSGQLSVLQP 1391

Query: 885  LDYEAFPDQEASITFLVEAFDIYGTMPPGIATVTVIVKDMNDYPPVFSKRIYKGMVAPDA 944
            L  +    Q   +T                ATVTV V + N+ PP F    Y   ++  A
Sbjct: 1390 LYLDQDRTQTYQLTITARDLGFPSRAATNTATVTVAV-NRNNNPPFFINTPYDVTISTPA 1214

Query: 945  VKGTPITTVYAEDADPPGMPASRVRYRV--DDVQFPYPASIFDVEEDSG-RVVTRVNLNE 1001
              GT +  V   DAD    P + V  +V  DD    Y    F +  D   RV    NLN 
Sbjct: 1213 ASGTSVIPVTVTDADSVA-PFNTVSLQVIGDDSAPIY----FSLGNDRIIRVSNVSNLNT 1049

Query: 1002 EPTTIFKLVVVAFDDGEPVMSSSATVRILVLHPGEIPRFTQEEYRPPPVSELAARGTVVG 1061
            +  T +++ ++A D G P  +++ATV I V      P+FT        + E AA GT + 
Sbjct: 1048 DTATFYRMRLLATDFGYPSRTATATVGITVRRNLFSPQFTNTNTIRVTIPETAAIGTFIT 869

Query: 1062 VISAA-----AINQSIVYSIVA-GNEEDKFGINNVTGVIYVNSPLDYETRTSYVLRVQAD 1115
             ++A      A N    +S+V  G+  + F IN + G I + + ++    + Y LRV   
Sbjct: 868  DLNATDSDTDAPNNEFQFSLVGVGDSVNFFFINPLDGRITLLNSVENTVNSGYQLRV--- 698

Query: 1116 SLEVVLANLRVPSKSN---TAKVYIEIQDEND-HPPVFQKKFYIGGVSEDARMFASVLRV 1171
                     RV    N    ++  +E+    D    VF    Y   +SE+      V  V
Sbjct: 697  ---------RVTDGGNPQLFSETLVEVTVVRDTETLVFTLPRYTVDISENLAENRIVTSV 545

Query: 1172 KATDRDTGNYSAMAYRLIIPPIKEGKEGFVVETYTG--LIKTAMLFHNMRRSYFKFQVIA 1229
             A  +D+  Y    Y        +G + F + + TG   IKT +     R++ +   V A
Sbjct: 544  VAQPQDSVTYRLTGY-------SDGPDYFNISSSTGSIFIKTDLRSDKNRKTSYLLGVEA 386

Query: 1230 TDDYGKGLSG 1239
            T  + +  +G
Sbjct: 385  TRAFRQASNG 356

 Score = 55.8 bits (133), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 98/371 (26%), Positives = 153/371 (41%), Gaps = 28/371 (7%)
 Frame = -3

Query: 519  YDVYVYTDMSPGDSVIQLTAVDAD-EGSNGEISYEILVGGKG--DFVINKTTGLVSIAPG 575
            Y V V  D   GD  +Q+TA+DAD    N  ++Y +    K    F +  ++G +S+   
Sbjct: 1570 YSVGVSEDRVVGDPFLQVTALDADFTAPNNLVTYTLAGNSKALEYFQVGSSSGQLSVLQP 1391

Query: 576  VELIVG--QTYALTVQASDNAPPAERRHSICTVYIEVLPPNNQSPPRFPQLMYSLEVSEA 633
            + L     QTY LT+ A D   P+    +  TV + V   NN  PP F    Y + +S  
Sbjct: 1390 LYLDQDRTQTYQLTITARDLGFPSRAATNTATVTVAVNRNNN--PPFFINTPYDVTISTP 1217

Query: 634  MRIGAILLNLQATDRE-------------GD---PITYAIENGDPQRVFNLSETTGILSL 677
               G  ++ +  TD +             GD   PI +++ N    RV N+S        
Sbjct: 1216 AASGTSVIPVTVTDADSVAPFNTVSLQVIGDDSAPIYFSLGNDRIIRVSNVSN------- 1058

Query: 678  GKALDRESTDRYILIVTASD-GRPDGTSXXXXXXXXXXXXXXXPVFDPYLPRNLSVVEEE 736
               L+ ++   Y + + A+D G P  T+               P F       +++ E  
Sbjct: 1057 ---LNTDTATFYRMRLLATDFGYPSRTATATVGITVRRNLFS-PQFTNTNTIRVTIPETA 890

Query: 737  A-NAFVGQVRATDPDAGI-NGQVHYSL---GNFNNLFRITS-NGSIYTAVKLNREARDHY 790
            A   F+  + ATD D    N +  +SL   G+  N F I   +G I     +       Y
Sbjct: 889  AIGTFITDLNATDSDTDAPNNEFQFSLVGVGDSVNFFFINPLDGRITLLNSVENTVNSGY 710

Query: 791  ELVVVATDGAVHPRHSTLTLYIKVLDIDDNSPVFTNSTYTVVVEENLPAGTSFLQIEAKD 850
            +L V  TDG  +P+  + TL    +  D  + VFT   YTV + ENL        + A+ 
Sbjct: 709  QLRVRVTDGG-NPQLFSETLVEVTVVRDTETLVFTLPRYTVDISENLAENRIVTSVVAQP 533

Query: 851  VDLGANVSYRI 861
             D   +V+YR+
Sbjct: 532  QD---SVTYRL 509

 Score = 46.6 bits (109), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 67/252 (26%), Positives = 105/252 (41%), Gaps = 21/252 (8%)
 Frame = -3

Query: 468  LTLLQPV--DREEQQTYTFLITA----FDGVQESEPVVVNIRVMDANDNTPTFPEISYDV 521
            L++LQP+  D++  QTY   ITA    F     +    V + V + N+N P F    YDV
Sbjct: 1408 LSVLQPLYLDQDRTQTYQLTITARDLGFPSRAATNTATVTVAV-NRNNNPPFFINTPYDV 1232

Query: 522  YVYTDMSPGDSVIQLTAVDADEGSN---------GEISYEILVGGKGDFVINKTTGLVSI 572
             + T  + G SVI +T  DAD  +          G+ S  I      D +I      VS 
Sbjct: 1231 TISTPAASGTSVIPVTVTDADSVAPFNTVSLQVIGDDSAPIYFSLGNDRIIR-----VSN 1067

Query: 573  APGVELIVGQTYALTVQASDNAPPAERRHSICTVYIEVLPPNNQSPPRFPQL-MYSLEVS 631
               +       Y + + A+D   P+  R +  TV I V    N   P+F       + + 
Sbjct: 1066 VSNLNTDTATFYRMRLLATDFGYPS--RTATATVGITVR--RNLFSPQFTNTNTIRVTIP 899

Query: 632  EAMRIGAILLNLQATDREGDP----ITYAIEN-GDPQRVFNLSETTGILSLGKALDREST 686
            E   IG  + +L ATD + D       +++   GD    F ++   G ++L  +++    
Sbjct: 898  ETAAIGTFITDLNATDSDTDAPNNEFQFSLVGVGDSVNFFFINPLDGRITLLNSVENTVN 719

Query: 687  DRYILIVTASDG 698
              Y L V  +DG
Sbjct: 718  SGYQLRVRVTDG 683

 Score = 42.7 bits (99), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 33/121 (27%), Positives = 60/121 (49%)
 Frame = -1

Query: 1129 KSNTAKVYIEIQDENDHPPVFQKKFYIGGVSEDARMFASVLRVKATDRDTGNYSAMAYRL 1188
            ++ TA V I ++  ND+PP+F ++ Y   +SE   + +SV+++ A+D DT +   + Y L
Sbjct: 363  QTATADVEISVR-RNDNPPIFSRQIYPAVISEYTALGSSVVQLVASDADTQD--VLKYSL 193

Query: 1189 IIPPIKEGKEGFVVETYTGLIKTAMLFHNMRRSYFKFQVIATDDYGKGLSGKADVLVSVV 1248
            +        + F +   TGLI    L    + S + F V  +D      +  A V V+++
Sbjct: 192  LTS--SGVTDYFYLGPSTGLISLRTLLLGQQASRYTFDVQVSDQSDPERTDTATVDVTIL 19

Query: 1249 N 1249
             
Sbjct: 18   R 16

 Score = 42.4 bits (98), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 36/109 (33%), Positives = 51/109 (46%), Gaps = 5/109 (4%)
 Frame = -1

Query: 508 NDNTPTFPEISYDVYVYTDMSPGDSVIQLTAVDADEGSNGEISYEILV--GGKGDFVINK 565
           NDN P F    Y   +    + G SV+QL A DAD  +   + Y +L   G    F +  
Sbjct: 324 NDNPPIFSRQIYPAVISEYTALGSSVVQLVASDAD--TQDVLKYSLLTSSGVTDYFYLGP 151

Query: 566 TTGLVSIAPGVELIVGQT---YALTVQASDNAPPAERRHSICTVYIEVL 611
           +TGL+S+     L++GQ    Y   VQ SD + P   R    TV + +L
Sbjct: 150 STGLISLR---TLLLGQQASRYTFDVQVSDQSDP--ERTDTATVDVTIL 19

 Score = 42.0 bits (97), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 40/125 (32%), Positives = 59/125 (47%), Gaps = 2/125 (1%)
 Frame = -1

Query: 804 RHSTLTLYIKV-LDIDDNSPVFTNSTYTVVVEENLPAGTSFLQIEAKDVDLGANVSYR-I 861
           RH T T  +++ +  +DN P+F+   Y  V+ E    G+S +Q+ A D D    + Y  +
Sbjct: 369 RHQTATADVEISVRRNDNPPIFSRQIYPAVISEYTALGSSVVQLVASDADTQDVLKYSLL 190

Query: 862 RSPEVKHLFALHPFTGELSLLRSLDYEAFPDQEASITFLVEAFDIYGTMPPGIATVTVIV 921
            S  V   F L P TG +S LR+L       Q +  TF V+  D   + P    T TV V
Sbjct: 189 TSSGVTDYFYLGPSTGLIS-LRTL---LLGQQASRYTFDVQVSD--QSDPERTDTATVDV 28

Query: 922 KDMND 926
             + D
Sbjct: 27  TILRD 13

 Score = 41.6 bits (96), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 29/100 (29%), Positives = 49/100 (49%), Gaps = 2/100 (2%)
 Frame = -1

Query: 600 RHSICTVYIEVLPPNNQSPPRFPQLMYSLEVSEAMRIGAILLNLQATDREG-DPITYA-I 657
           RH   T  +E+    N +PP F + +Y   +SE   +G+ ++ L A+D +  D + Y+ +
Sbjct: 369 RHQTATADVEISVRRNDNPPIFSRQIYPAVISEYTALGSSVVQLVASDADTQDVLKYSLL 190

Query: 658 ENGDPQRVFNLSETTGILSLGKALDRESTDRYILIVTASD 697
            +      F L  +TG++SL   L  +   RY   V  SD
Sbjct: 189 TSSGVTDYFYLGPSTGLISLRTLLLGQQASRYTFDVQVSD 70

 Score = 33.5 bits (75), Expect = 0.93,   Method: Compositional matrix adjust.
 Identities = 25/109 (22%), Positives = 50/109 (45%)
 Frame = -1

Query: 925  NDYPPVFSKRIYKGMVAPDAVKGTPITTVYAEDADPPGMPASRVRYRVDDVQFPYPASIF 984
            ND PP+FS++IY  +++     G+ +  + A DAD   +    ++Y +  +        F
Sbjct: 324  NDNPPIFSRQIYPAVISEYTALGSSVVQLVASDADTQDV----LKYSL--LTSSGVTDYF 163

Query: 985  DVEEDSGRVVTRVNLNEEPTTIFKLVVVAFDDGEPVMSSSATVRILVLH 1033
             +   +G +  R  L  +  + +   V   D  +P  + +ATV + +L 
Sbjct: 162  YLGPSTGLISLRTLLLGQQASRYTFDVQVSDQSDPERTDTATVDVTILR 16
>14391
          Length = 642

 Score = 72.0 bits (175), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 66/191 (34%), Positives = 96/191 (50%), Gaps = 6/191 (3%)
 Frame = +1

Query: 748 DPDAGINGQVHYSLGNFNNLFRI-TSNGSIYTAVKLNREARDHYELVVVATDGAVHPRHS 806
           D DAG N ++ Y + N  + F I T  G IYT   L+RE    Y   + A D +  P  +
Sbjct: 1   DVDAGDNARLIYGMENNGDTFTIDTMLGDIYTTRFLDRETTPRYVFNIYAYDKSASPLTA 180

Query: 807 TLTLYIKVLDIDDNSPVFTNSTYTVVVEENLPAGTSFLQIEA--KDVDLGANVSYRIRSP 864
             T+ + V D +D  PVF NS+Y   V+E  P G+    ++A  KD+ L A V Y +   
Sbjct: 181 VTTVVVNVADKNDMKPVFLNSSYHFHVDERTPPGSMIGDVKAVDKDIGLNARVEYYMVPS 360

Query: 865 EVKHLFALHPFT-GELSLLRSLDYEAFPDQEASITFLVEAFDIYGTMPPGIAT--VTVIV 921
           + +  F +   T G + +   +DYE         TF+V A D+ GT PP  +T  VT+ V
Sbjct: 361 KSRPRFPITVNTSGAILVTDEVDYE----MSNLFTFMVAAVDL-GT-PPRNSTCHVTIEV 522

Query: 922 KDMNDYPPVFS 932
            D ND+ PV +
Sbjct: 523 MDKNDHSPVIT 555

 Score = 55.8 bits (133), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 55/184 (29%), Positives = 84/184 (45%), Gaps = 11/184 (5%)
 Frame = +1

Query: 653 ITYAIEN-GDPQRVFNLSETTGILSLGKALDRESTDRYILIVTASDGRPDG-TSXXXXXX 710
           + Y +EN GD    F +    G +   + LDRE+T RY+  + A D      T+      
Sbjct: 28  LIYGMENNGD---TFTIDTMLGDIYTTRFLDRETTPRYVFNIYAYDKSASPLTAVTTVVV 198

Query: 711 XXXXXXXXXPVFDPYLPRNLSV---VEEEA--NAFVGQVRATDPDAGINGQVHYSL--GN 763
                    PVF      N S    V+E     + +G V+A D D G+N +V Y +    
Sbjct: 199 NVADKNDMKPVF-----LNSSYHFHVDERTPPGSMIGDVKAVDKDIGLNARVEYYMVPSK 363

Query: 764 FNNLFRITSN--GSIYTAVKLNREARDHYELVVVATDGAVHPRHSTLTLYIKVLDIDDNS 821
               F IT N  G+I    +++ E  + +  +V A D    PR+ST  + I+V+D +D+S
Sbjct: 364 SRPRFPITVNTSGAILVTDEVDYEMSNLFTFMVAAVDLGTPPRNSTCHVTIEVMDKNDHS 543

Query: 822 PVFT 825
           PV T
Sbjct: 544 PVIT 555

 Score = 52.8 bits (125), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 49/160 (30%), Positives = 71/160 (44%), Gaps = 6/160 (3%)
 Frame = +1

Query: 465 TRYLTLLQPVDREEQQTYTFLITAFDGVQESEPVVVNIRVM----DANDNTPTFPEISYD 520
           TR+L      DRE    Y F I A+D  + + P+     V+    D ND  P F   SY 
Sbjct: 97  TRFL------DRETTPRYVFNIYAYD--KSASPLTAVTTVVVNVADKNDMKPVFLNSSYH 252

Query: 521 VYVYTDMSPGDSVIQLTAVDADEGSNGEISYEILVG-GKGDFVIN-KTTGLVSIAPGVEL 578
            +V     PG  +  + AVD D G N  + Y ++    +  F I   T+G + +   V+ 
Sbjct: 253 FHVDERTPPGSMIGDVKAVDKDIGLNARVEYYMVPSKSRPRFPITVNTSGAILVTDEVDY 432

Query: 579 IVGQTYALTVQASDNAPPAERRHSICTVYIEVLPPNNQSP 618
            +   +   V A D   P   R+S C V IEV+  N+ SP
Sbjct: 433 EMSNLFTFMVAAVDLGTPP--RNSTCHVTIEVMDKNDHSP 546

 Score = 47.8 bits (112), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 47/173 (27%), Positives = 74/173 (42%), Gaps = 8/173 (4%)
 Frame = +1

Query: 984  FDVEEDSGRVVTRVNLNEEPTTIFKLVVVAFDDGEPVMSSSATVRILVLHPGEI-PRFTQ 1042
            F ++   G + T   L+ E T  +   + A+D     +++  TV + V    ++ P F  
Sbjct: 61   FTIDTMLGDIYTTRFLDRETTPRYVFNIYAYDKSASPLTAVTTVVVNVADKNDMKPVFLN 240

Query: 1043 EEY------RPPPVSELAARGTVVGVISAAAINQSIVYSIVAGNEEDKFGIN-NVTGVIY 1095
              Y      R PP S +   G V  V     +N  + Y +V      +F I  N +G I 
Sbjct: 241  SSYHFHVDERTPPGSMI---GDVKAVDKDIGLNARVEYYMVPSKSRPRFPITVNTSGAIL 411

Query: 1096 VNSPLDYETRTSYVLRVQADSLEVVLANLRVPSKSNTAKVYIEIQDENDHPPV 1148
            V   +DYE    +   V A        +L  P +++T  V IE+ D+NDH PV
Sbjct: 412  VTDEVDYEMSNLFTFMVAA-------VDLGTPPRNSTCHVTIEVMDKNDHSPV 549

 Score = 43.9 bits (102), Expect = 6e-04,   Method: Compositional matrix adjust.
 Identities = 30/98 (30%), Positives = 49/98 (50%)
 Frame = +1

Query: 144 DRNDNSPTFKHESYYATVNELTPVGTTIFTGFSGDNGATDIDDGPNGQIEYVIQYNPEDP 203
           D+ND  P F + SY+  V+E TP G+ I     GD  A D D G N ++EY +  +   P
Sbjct: 208 DKNDMKPVFLNSSYHFHVDERTPPGSMI-----GDVKAVDKDIGLNARVEYYMVPSKSRP 372

Query: 204 TSNDTFEIPLMLTGNVVLRKRLNYEDKTRYYVIIQAND 241
                F I +  +G +++   ++YE    +  ++ A D
Sbjct: 373 ----RFPITVNTSGAILVTDEVDYEMSNLFTFMVAAVD 474

 Score = 40.4 bits (93), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 47/193 (24%), Positives = 79/193 (40%)
 Frame = +1

Query: 1066 AAINQSIVYSIVAGNEEDKFGINNVTGVIYVNSPLDYETRTSYVLRVQADSLEVVLANLR 1125
            A  N  ++Y +   N  D F I+ + G IY    LD ET   YV  + A        +  
Sbjct: 10   AGDNARLIYGM--ENNGDTFTIDTMLGDIYTTRFLDRETTPRYVFNIYA-------YDKS 162

Query: 1126 VPSKSNTAKVYIEIQDENDHPPVFQKKFYIGGVSEDARMFASVLRVKATDRDTGNYSAMA 1185
                +    V + + D+ND  PVF    Y   V E     + +  VKA D+D G  + + 
Sbjct: 163  ASPLTAVTTVVVNVADKNDMKPVFLNSSYHFHVDERTPPGSMIGDVKAVDKDIGLNARVE 342

Query: 1186 YRLIIPPIKEGKEGFVVETYTGLIKTAMLFHNMRRSYFKFQVIATDDYGKGLSGKADVLV 1245
            Y + +P     +    V T   ++ T  + + M  + F F V A D      +    V +
Sbjct: 343  YYM-VPSKSRPRFPITVNTSGAILVTDEVDYEM-SNLFTFMVAAVDLGTPPRNSTCHVTI 516

Query: 1246 SVVNQLDMQVIVS 1258
             V+++ D   +++
Sbjct: 517  EVMDKNDHSPVIT 555

 Score = 36.2 bits (82), Expect = 0.14,   Method: Compositional matrix adjust.
 Identities = 52/184 (28%), Positives = 74/184 (40%), Gaps = 1/184 (0%)
 Frame = +1

Query: 850  DVDLGANVSYRIRSPEVKHLFALHPFTGELSLLRSLDYEAFPDQEASITFLVEAFDIYGT 909
            DVD G N             F +    G++   R LD E  P       F + A+D   +
Sbjct: 1    DVDAGDNARLIYGMENNGDTFTIDTMLGDIYTTRFLDRETTP----RYVFNIYAYDKSAS 168

Query: 910  MPPGIATVTVIVKDMNDYPPVFSKRIYKGMVAPDAVKGTPITTVYAEDADPPGMPASRVR 969
                + TV V V D ND  PVF    Y   V      G+ I  V A D D  G+ A    
Sbjct: 169  PLTAVTTVVVNVADKNDMKPVFLNSSYHFHVDERTPPGSMIGDVKAVDKD-IGLNARVEY 345

Query: 970  YRVDDVQFP-YPASIFDVEEDSGRVVTRVNLNEEPTTIFKLVVVAFDDGEPVMSSSATVR 1028
            Y V     P +P ++      SG ++    ++ E + +F  +V A D G P  +S+  V 
Sbjct: 346  YMVPSKSRPRFPITV----NTSGAILVTDEVDYEMSNLFTFMVAAVDLGTPPRNSTCHVT 513

Query: 1029 ILVL 1032
            I V+
Sbjct: 514  IEVM 525
>37991
          Length = 843

 Score = 63.9 bits (154), Expect = 5e-10,   Method: Compositional matrix adjust.
 Identities = 54/191 (28%), Positives = 87/191 (45%), Gaps = 8/191 (4%)
 Frame = +2

Query: 790 YELVVVATD---GAVHPRHSTLTLYIKVLDIDDNSPVFTNSTYTVVVEENLPAGTSFLQI 846
           Y L V A D   G+   + ST+ + I + D++DN P F  +TY+    E   AG + L  
Sbjct: 239 YSLTVTAADDLAGSADEKSSTVVIAIAITDVNDNYPNFNPATYSDSPLETAAAGGTLLTX 418

Query: 847 EAKDVDLGAN--VSYRIRSPEVKHLFALHPFTGELSLLRSLDYEAFPDQEASITFLVEAF 904
              D D GAN  +   I S    + F+L     +L +  +LDYE   + +     ++EA 
Sbjct: 419 TVTDADDGANAVLVLSIASGNTNNAFSLSG--NDLVIANNLDYETTKNYD----LIIEAA 580

Query: 905 DIYGTMPPGI---ATVTVIVKDMNDYPPVFSKRIYKGMVAPDAVKGTPITTVYAEDADPP 961
           D  GT P  +   A +++ V+  N+ PPV +   +   +  D   G+ I T  A D D  
Sbjct: 581 D-SGT-PTALTSQARISISVQAANEDPPVLTDTTFAATIPEDQAVGSLIYTATATDPDQD 754

Query: 962 GMPASRVRYRV 972
           G     + + +
Sbjct: 755 GNNDGTITFSI 787

 Score = 60.1 bits (144), Expect = 9e-09,   Method: Compositional matrix adjust.
 Identities = 51/195 (26%), Positives = 88/195 (45%), Gaps = 14/195 (7%)
 Frame = +2

Query: 481 TYTFLITAFDGV-----QESEPVVVNIRVMDANDNTPTFPEISYDVYVYTDMSPGDSVIQ 535
           TY+  +TA D +     ++S  VV+ I + D NDN P F   +Y        + G +++ 
Sbjct: 236 TYSLTVTAADDLAGSADEKSSTVVIAIAITDVNDNYPNFNPATYSDSPLETAAAGGTLLT 415

Query: 536 LTAVDADEGSNGEISYEILVGGKGDFVINKTTGLVSIAPGVELIVGQTYALTVQASDNAP 595
            T  DAD+G+N  +   I  G   +        LV IA  ++    + Y L ++A+D+  
Sbjct: 416 XTVTDADDGANAVLVLSIASGNTNNAFSLSGNDLV-IANNLDYETTKNYDLIIEAADSGT 592

Query: 596 P----AERRHSICTVYIEVLPPNNQSPPRFPQLMYSLEVSEAMRIGAILLNLQATDREGD 651
           P    ++ R SI       +   N+ PP      ++  + E   +G+++    ATD + D
Sbjct: 593 PTALTSQARISIS------VQAANEDPPVLTDTTFAATIPEDQAVGSLIYTATATDPDQD 754

Query: 652 -----PITYAIENGD 661
                 IT++I  GD
Sbjct: 755 GNNDGTITFSISAGD 799

 Score = 54.7 bits (130), Expect = 4e-07,   Method: Compositional matrix adjust.
 Identities = 47/179 (26%), Positives = 79/179 (44%), Gaps = 8/179 (4%)
 Frame = +2

Query: 1007 FKLVVVAFDDGEPVMSSSATVRILVLHPGEI----PRFTQEEYRPPPVSELAARGTVVGV 1062
            + L V A DD        ++  ++ +   ++    P F    Y   P+   AA GT++  
Sbjct: 239  YSLTVTAADDLAGSADEKSSTVVIAIAITDVNDNYPNFNPATYSDSPLETAAAGGTLLTX 418

Query: 1063 ISAAA---INQSIVYSIVAGNEEDKFGINNVTGVIYVNSPLDYETRTSYVLRVQADSLEV 1119
                A    N  +V SI +GN  + F ++    VI  N  LDYET  +Y L ++A     
Sbjct: 419  TVTDADDGANAVLVLSIASGNTNNAFSLSGNDLVIANN--LDYETTKNYDLIIEA----- 577

Query: 1120 VLANLRVPSK-SNTAKVYIEIQDENDHPPVFQKKFYIGGVSEDARMFASVLRVKATDRD 1177
              A+   P+  ++ A++ I +Q  N+ PPV     +   + ED  + + +    ATD D
Sbjct: 578  --ADSGTPTALTSQARISISVQAANEDPPVLTDTTFAATIPEDQAVGSLIYTATATDPD 748

 Score = 42.7 bits (99), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 26/69 (37%), Positives = 39/69 (56%), Gaps = 3/69 (4%)
 Frame = +3

Query: 508 NDNTPTFPEISYDVY-VYTDMSPGDSVIQLTAVDADEG-SNGEISYEILVGG-KGDFVIN 564
           N++TPTFP   Y    V    S G   + + A D+D G  +G + Y I  G  +GDF+I+
Sbjct: 3   NEDTPTFPAGGYATTNVLESESVGTVALTVAAADSDTGLYHGTVLYSITGGNTQGDFIID 182

Query: 565 KTTGLVSIA 573
            +TG +S+A
Sbjct: 183 SSTGAISVA 209

 Score = 42.0 bits (97), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 36/119 (30%), Positives = 53/119 (44%), Gaps = 1/119 (0%)
 Frame = +2

Query: 125 CVNKKVGTVIYHEVRIVVRDRNDNSPTFKHESYYATVNELTPVGTTIFTGFSGDNGATDI 184
             ++K  TV+   + I + D NDN P F   +Y  +  E    G T+ T        TD 
Sbjct: 278 SADEKSSTVV---IAIAITDVNDNYPNFNPATYSDSPLETAAAGGTLLTXT-----VTDA 433

Query: 185 DDGPNGQIEYVIQYNPEDPTSNDTFEIPLMLTGN-VVLRKRLNYEDKTRYYVIIQANDR 242
           DDG N  +   I        +N+ F     L+GN +V+   L+YE    Y +II+A D 
Sbjct: 434 DDGANAVLVLSIASG----NTNNAFS----LSGNDLVIANNLDYETTKNYDLIIEAADS 586

 Score = 38.9 bits (89), Expect = 0.018,   Method: Compositional matrix adjust.
 Identities = 28/81 (34%), Positives = 41/81 (50%), Gaps = 6/81 (7%)
 Frame = +3

Query: 1036 EIPRFTQEEYRPPPVSELAARGTVVGVISAA-----AINQSIVYSIVAGNEEDKFGINNV 1090
            + P F    Y    V E  + GTV   ++AA       + +++YSI  GN +  F I++ 
Sbjct: 9    DTPTFPAGGYATTNVLESESVGTVALTVAAADSDTGLYHGTVLYSITGGNTQGDFIIDSS 188

Query: 1091 TGVIYVNSPLDYE-TRTSYVL 1110
            TG I V  PLD E TR + +L
Sbjct: 189  TGAISVAKPLDREATRLTRLL 251
>34098
          Length = 1349

 Score = 63.9 bits (154), Expect = 6e-10,   Method: Compositional matrix adjust.
 Identities = 41/113 (36%), Positives = 62/113 (54%), Gaps = 2/113 (1%)
 Frame = +3

Query: 745 RATDPDAGINGQVHYSL-GNFNNLFRITSNGSIYT-AVKLNREARDHYELVVVATDGAVH 802
           R+  PD    GQV   L G  ++ F I ++G+I   A+ L+RE+ D Y L+V A DG VH
Sbjct: 738 RSGGPDPDTTGQVQLRLRGRGDDKFDIQNDGTIVAVALPLDRESEDRYTLIVTADDG-VH 914

Query: 803 PRHSTLTLYIKVLDIDDNSPVFTNSTYTVVVEENLPAGTSFLQIEAKDVDLGA 855
              +++T+ I   D +DN P FT   Y+  V E+   G +  ++ A D D+G 
Sbjct: 915 TTSASVTIAIS--DSNDNRPRFTQDFYSFDVHEDTDRGATVARVTALDADMGG 1067

 Score = 60.5 bits (145), Expect = 6e-09,   Method: Compositional matrix adjust.
 Identities = 53/194 (27%), Positives = 89/194 (45%), Gaps = 8/194 (4%)
 Frame = +2

Query: 741 VGQVRATDPDAGINGQVHYSLGNFNNLFRITSNGSIYTAVKLNREARDHYELVVVATDGA 800
           V  V A D D+G NG+V Y+L ++ +LF + ++    + V+        Y L V+A D A
Sbjct: 92  VATVFADDADSGDNGRVSYTLLSYTSLFSVHASTGQISLVQDMPTMPYSYRLRVMAIDNA 271

Query: 801 --VHPRHSTLTLYIKVLDIDDNSPVFTNSTYTVVVEENLPAGTSFLQIEAKDVDLGANVS 858
                + ST T    +L   ++ PVF   TY+  + E+ P  +S  ++ A     G ++ 
Sbjct: 272 DSGQNKKSTETTISLLLSSSEDGPVFQPRTYSKFLSEDDPPNSSVFKVSASATRPGGSIE 451

Query: 859 YRI-----RSPEVKHLFALHPFTGELSLLRSLDYEAFPDQEASITFLVEAFDIYGTMPPG 913
           Y +     +  +   LF +   +G ++    LD EA  D+    T  + A +  G  P  
Sbjct: 452 YYLTGITSQGQQRGGLFRVDSSSGVVTTTTKLDREALGDE---FTLSITAVEKGGNSPRN 622

Query: 914 IAT-VTVIVKDMND 926
             T  TV + D+ND
Sbjct: 623 RTTQATVTLTDIND 664

 Score = 56.2 bits (134), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 38/101 (37%), Positives = 47/101 (46%)
 Frame = +3

Query: 1079 GNEEDKFGINNVTGVIYVNSPLDYETRTSYVLRVQADSLEVVLANLRVPSKSNTAKVYIE 1138
            G  +DKF I N   ++ V  PLD E+   Y L V AD              + +A V I 
Sbjct: 792  GRGDDKFDIQNDGTIVAVALPLDRESEDRYTLIVTADD----------GVHTTSASVTIA 941

Query: 1139 IQDENDHPPVFQKKFYIGGVSEDARMFASVLRVKATDRDTG 1179
            I D ND+ P F + FY   V ED    A+V RV A D D G
Sbjct: 942  ISDSNDNRPRFTQDFYSFDVHEDTDRGATVARVTALDADMG 1064

 Score = 55.8 bits (133), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 30/72 (41%), Positives = 43/72 (59%)
 Frame = +3

Query: 473 PVDREEQQTYTFLITAFDGVQESEPVVVNIRVMDANDNTPTFPEISYDVYVYTDMSPGDS 532
           P+DRE +  YT ++TA DGV  +    V I + D+NDN P F +  Y   V+ D   G +
Sbjct: 852 PLDRESEDRYTLIVTADDGVHTTS-ASVTIAISDSNDNRPRFTQDFYSFDVHEDTDRGAT 1028

Query: 533 VIQLTAVDADEG 544
           V ++TA+DAD G
Sbjct: 1029VARVTALDADMG 1064

 Score = 52.0 bits (123), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 33/92 (35%), Positives = 52/92 (56%), Gaps = 3/92 (3%)
 Frame = +1

Query: 749  PDAGINGQVHYSLGN--FNNLFRITSNGSIYTAVK-LNREARDHYELVVVATDGAVHPRH 805
            P  G N +V Y L +    + F++ S    +T +  L+ E R  Y L VVA DG   P  
Sbjct: 1054 PTWGENARVTYDLLSDWATDRFQLDSVLGTFTLIGGLDYELRQLYTLRVVARDGGSPPMS 1233

Query: 806  STLTLYIKVLDIDDNSPVFTNSTYTVVVEENL 837
            +T T+Y+ V+D++DN P F  ++YT ++ EN+
Sbjct: 1234 TTTTVYMNVVDVNDNQPEFDPASYTQLLYENV 1329

 Score = 49.3 bits (116), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 50/171 (29%), Positives = 84/171 (49%), Gaps = 7/171 (4%)
 Frame = +2

Query: 532 SVIQLTAVDADEGSNGEISYEILVGGKGDFVINKTTGLVSIAPGVELIVGQTYALTVQAS 591
           +V  + A DAD G NG +SY +L      F ++ +TG +S+   +  +   +Y L V A 
Sbjct: 89  AVATVFADDADSGDNGRVSYTLL-SYTSLFSVHASTGQISLVQDMPTMP-YSYRLRVMAI 262

Query: 592 DNAPPAERRHSICTVYIEVLPPNNQSPPRFPQLMYSLEVSEAMRIGAILLNLQAT-DREG 650
           DNA   + + S  T  I +L  +++  P F    YS  +SE     + +  + A+  R G
Sbjct: 263 DNADSGQNKKSTETT-ISLLLSSSEDGPVFQPRTYSKFLSEDDPPNSSVFKVSASATRPG 439

Query: 651 DPITY---AIENGDPQR--VFNLSETTGILSLGKALDRES-TDRYILIVTA 695
             I Y    I +   QR  +F +  ++G+++    LDRE+  D + L +TA
Sbjct: 440 GSIEYYLTGITSQGQQRGGLFRVDSSSGVVTTTTKLDREALGDEFTLSITA 592

 Score = 45.1 bits (105), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 29/100 (29%), Positives = 46/100 (46%)
 Frame = +1

Query: 1069 NQSIVYSIVAGNEEDKFGINNVTGVIYVNSPLDYETRTSYVLRVQADSLEVVLANLRVPS 1128
            N  + Y +++    D+F +++V G   +   LDYE R  Y LR       VV  +   P 
Sbjct: 1069 NARVTYDLLSDWATDRFQLDSVLGTFTLIGGLDYELRQLYTLR-------VVARDGGSPP 1227

Query: 1129 KSNTAKVYIEIQDENDHPPVFQKKFYIGGVSEDARMFASV 1168
             S T  VY+ + D ND+ P F    Y   + E+  +  +V
Sbjct: 1228 MSTTTTVYMNVVDVNDNQPEFDPASYTQLLYENVNITHTV 1347

 Score = 36.2 bits (82), Expect = 0.13,   Method: Compositional matrix adjust.
 Identities = 17/33 (51%), Positives = 22/33 (66%)
 Frame = +3

Query: 666 FNLSETTGILSLGKALDRESTDRYILIVTASDG 698
           F++     I+++   LDRES DRY LIVTA DG
Sbjct: 810 FDIQNDGTIVAVALPLDRESEDRYTLIVTADDG 908
>18709
          Length = 501

 Score = 61.2 bits (147), Expect = 4e-09,   Method: Compositional matrix adjust.
 Identities = 48/157 (30%), Positives = 75/157 (47%), Gaps = 9/157 (5%)
 Frame = +2

Query: 741 VGQVRATDPDAGINGQVHYSL-GNFNNLFRIT-SNGSIYTAVKLNREARDHYELVVVATD 798
           + QV A DPD G NG + YSL  N  + F I    G++    K +RE R HY ++V A D
Sbjct: 8   IFQVLAMDPDMGNNGNITYSLLENPESAFAIDPVTGTLRAMKKFDRENRSHYRVMVQAKD 187

Query: 799 GAVHPRHSTLTLYIKVLDIDDNSPVFTNSTYTVVVEENLPAGT--SFLQIEAKDVDLGAN 856
                  S  T+++ + D++D+   F  S +   VEE  P GT    L++    VDL   
Sbjct: 188 RGTPSMTSIATIHVNISDVNDSPTHFAQSHFNFYVEEERPRGTIVDILRV----VDLDEK 355

Query: 857 VSYRIRSPEVKHL-----FALHPFTGELSLLRSLDYE 888
            S +++   +        F++   +G ++  R LD E
Sbjct: 356 TSNQLQYSFLSEFAAPSQFSIDVSSGRITTTRPLDRE 466

 Score = 47.0 bits (110), Expect = 7e-05,   Method: Compositional matrix adjust.
 Identities = 46/164 (28%), Positives = 78/164 (47%), Gaps = 3/164 (1%)
 Frame = +2

Query: 842  SFLQIEAKDVDLG--ANVSYRI-RSPEVKHLFALHPFTGELSLLRSLDYEAFPDQEASIT 898
            S  Q+ A D D+G   N++Y +  +PE    FA+ P TG L  ++  D E      +   
Sbjct: 5    SIFQVLAMDPDMGNNGNITYSLLENPE--SAFAIDPVTGTLRAMKKFDRE----NRSHYR 166

Query: 899  FLVEAFDIYGTMPPGIATVTVIVKDMNDYPPVFSKRIYKGMVAPDAVKGTPITTVYAEDA 958
             +V+A D        IAT+ V + D+ND P  F++  +   V  +  +GT +  +   D 
Sbjct: 167  VMVQAKDRGTPSMTSIATIHVNISDVNDSPTHFAQSHFNFYVEEERPRGTIVDILRVVDL 346

Query: 959  DPPGMPASRVRYRVDDVQFPYPASIFDVEEDSGRVVTRVNLNEE 1002
            D     +++++Y     +F  P S F ++  SGR+ T   L+ E
Sbjct: 347  DEK--TSNQLQYSFLS-EFAAP-SQFSIDVSSGRITTTRPLDRE 466

 Score = 45.4 bits (106), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 35/114 (30%), Positives = 52/114 (45%), Gaps = 2/114 (1%)
 Frame = +2

Query: 1069 NQSIVYSIVAGNEEDKFGINNVTGVIYVNSPLDYETRTSYVLRVQADSLEVVLANLRVPS 1128
            N +I YS++  N E  F I+ VTG +      D E R+ Y + VQA        +   PS
Sbjct: 47   NGNITYSLLE-NPESAFAIDPVTGTLRAMKKFDRENRSHYRVMVQA-------KDRGTPS 202

Query: 1129 KSNTAKVYIEIQDENDHPPVFQKKFYIGGVSED--ARMFASVLRVKATDRDTGN 1180
             ++ A +++ I D ND P  F +  +   V E+        +LRV   D  T N
Sbjct: 203  MTSIATIHVNISDVNDSPTHFAQSHFNFYVEEERPRGTIVDILRVVDLDEKTSN 364
>38442
          Length = 393

 Score = 58.9 bits (141), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 34/111 (30%), Positives = 60/111 (54%)
 Frame = -3

Query: 1078 AGNEEDKFGINNVTGVIYVNSPLDYETRTSYVLRVQADSLEVVLANLRVPSKSNTAKVYI 1137
            AG+     G+++  G++ V  PLD E  +SY L       +VV ++   P +S +  + I
Sbjct: 322  AGSTSSVDGVSSDLGIV-VEQPLDREKMSSYFL-------QVVASDGGFPQRSGSVNITI 167

Query: 1138 EIQDENDHPPVFQKKFYIGGVSEDARMFASVLRVKATDRDTGNYSAMAYRL 1188
             +QD ND+ P F ++ +   V+ED+    ++LR+ ATD D+ +  A+ Y  
Sbjct: 166  NVQDVNDNVPTFSRELFNITVNEDSPTGVAILRLNATDPDSSHNGALTYSF 14

 Score = 58.5 bits (140), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 33/95 (34%), Positives = 51/95 (53%), Gaps = 4/95 (4%)
 Frame = -3

Query: 463 GITRYLTLL--QPVDREEQQTYTFLITAFDGV--QESEPVVVNIRVMDANDNTPTFPEIS 518
           G++  L ++  QP+DRE+  +Y   + A DG   Q S  V + I V D NDN PTF    
Sbjct: 298 GVSSDLGIVVEQPLDREKMSSYFLQVVASDGGFPQRSGSVNITINVQDVNDNVPTFSREL 119

Query: 519 YDVYVYTDMSPGDSVIQLTAVDADEGSNGEISYEI 553
           +++ V  D   G ++++L A D D   NG ++Y  
Sbjct: 118 FNITVNEDSPTGVAILRLNATDPDSSHNGALTYSF 14

 Score = 57.0 bits (136), Expect = 7e-08,   Method: Compositional matrix adjust.
 Identities = 30/95 (31%), Positives = 51/95 (53%)
 Frame = -3

Query: 762 GNFNNLFRITSNGSIYTAVKLNREARDHYELVVVATDGAVHPRHSTLTLYIKVLDIDDNS 821
           G+ +++  ++S+  I     L+RE    Y L VVA+DG    R  ++ + I V D++DN 
Sbjct: 319 GSTSSVDGVSSDLGIVVEQPLDREKMSSYFLQVVASDGGFPQRSGSVNITINVQDVNDNV 140

Query: 822 PVFTNSTYTVVVEENLPAGTSFLQIEAKDVDLGAN 856
           P F+   + + V E+ P G + L++ A D D   N
Sbjct: 139 PTFSRELFNITVNEDSPTGVAILRLNATDPDSSHN 35

 Score = 39.3 bits (90), Expect = 0.015,   Method: Compositional matrix adjust.
 Identities = 24/57 (42%), Positives = 29/57 (50%)
 Frame = -3

Query: 138 VRIVVRDRNDNSPTFKHESYYATVNELTPVGTTIFTGFSGDNGATDIDDGPNGQIEY 194
           + I V+D NDN PTF  E +  TVNE +P G  I         ATD D   NG + Y
Sbjct: 175 ITINVQDVNDNVPTFSRELFNITVNEDSPTGVAILR-----LNATDPDSSHNGALTY 20

 Score = 33.9 bits (76), Expect = 0.73,   Method: Compositional matrix adjust.
 Identities = 20/70 (28%), Positives = 34/70 (48%), Gaps = 2/70 (2%)
 Frame = -3

Query: 892 DQEASITFLVEAFDIYGTMP--PGIATVTVIVKDMNDYPPVFSKRIYKGMVAPDAVKGTP 949
           D+E   ++ ++     G  P   G   +T+ V+D+ND  P FS+ ++   V  D+  G  
Sbjct: 256 DREKMSSYFLQVVASDGGFPQRSGSVNITINVQDVNDNVPTFSRELFNITVNEDSPTGVA 77

Query: 950 ITTVYAEDAD 959
           I  + A D D
Sbjct: 76  ILRLNATDPD 47

 Score = 33.5 bits (75), Expect = 0.97,   Method: Compositional matrix adjust.
 Identities = 32/104 (30%), Positives = 45/104 (43%), Gaps = 2/104 (1%)
 Frame = -3

Query: 660 GDPQRVFNLSETTGILSLGKALDRESTDRYILIVTASDGR-PDGTSXXXXXXXXXXXXXX 718
           G    V  +S   GI+ + + LDRE    Y L V ASDG  P  +               
Sbjct: 319 GSTSSVDGVSSDLGIV-VEQPLDREKMSSYFLQVVASDGGFPQRSGSVNITINVQDVNDN 143

Query: 719 XPVFDPYLPRNLSVVEEEANAF-VGQVRATDPDAGINGQVHYSL 761
            P F   L  N++V E+      + ++ ATDPD+  NG + YS 
Sbjct: 142 VPTFSREL-FNITVNEDSPTGVAILRLNATDPDSSHNGALTYSF 14
>12240
          Length = 977

 Score = 57.8 bits (138), Expect = 5e-08,   Method: Compositional matrix adjust.
 Identities = 42/136 (30%), Positives = 69/136 (50%), Gaps = 3/136 (2%)
 Frame = +1

Query: 1038 PRFTQEEYRPPPVSEL---AARGTVVGVISAAAINQSIVYSIVAGNEEDKFGINNVTGVI 1094
            P+F   E     V+EL   +  GTV+  + A +   +IVY+I+AGN +D F +N  +GV+
Sbjct: 4    PKFPSSEI----VTELKENSPAGTVLDAVRAES-QSTIVYTIIAGNTDDCFFLNXNSGVV 168

Query: 1095 YVNSPLDYETRTSYVLRVQADSLEVVLANLRVPSKSNTAKVYIEIQDENDHPPVFQKKFY 1154
                 +DYE    +       +L ++ AN  + S +    + + + DEND+ P F  + +
Sbjct: 169  STTRAIDYEHHHFF-------NLTILAAN--IVSATAVTHMLVHVGDENDNRPQFTAQAF 321

Query: 1155 IGGVSEDARMFASVLR 1170
             G VSE A   + VL 
Sbjct: 322  FGNVSESAEAGSMVLN 369

 Score = 42.7 bits (99), Expect(2) = 5e-05,   Method: Compositional matrix adjust.
 Identities = 39/127 (30%), Positives = 59/127 (46%), Gaps = 9/127 (7%)
 Frame = +2

Query: 584 YALTVQASDNAPP--AERRHSICTVYIEVLPPNNQSPPRFPQLMYSLEVSEAMRIGAILL 641
           +  TVQ  D   P  +    +   VYI  +   N +PPRF Q  Y+ +V         ++
Sbjct: 536 FNFTVQVHDRGVPRLSASAPAPVVVYITDI---NDTPPRFTQSSYTAKVVLPTYHDVRVV 706

Query: 642 NLQATDREG---DPITYAIENGDPQRVFNLSETTGILSLGKALDRESTDR----YILIVT 694
            ++A D +     P+TY+I  G+   VF ++  +G+L +      E TD     Y L V 
Sbjct: 707 KVEAEDPDTISTKPLTYSIAGGNEGSVFAINPQSGVLHV------EHTDHIQNSYELKVQ 868

Query: 695 ASDGRPD 701
           ASDGR D
Sbjct: 869 ASDGRYD 889

 Score = 24.3 bits (51), Expect(2) = 5e-05,   Method: Composition-based stats.
 Identities = 14/34 (41%), Positives = 18/34 (52%), Gaps = 1/34 (2%)
 Frame = +3

Query: 538 AVDADEGSNGEISYEIL-VGGKGDFVINKTTGLV 570
           A DAD G N  + YEI+    +  F I+  TG V
Sbjct: 396 ASDADAGENALLEYEIVDAEARKYFTIDVNTGAV 497

 Score = 42.0 bits (97), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 41/125 (32%), Positives = 59/125 (47%), Gaps = 7/125 (5%)
 Frame = +2

Query: 997  VNLNEEPTTIFKLVVVAFDDGEPVMSSSATVRILVLHPGEI----PRFTQEEYRPPPVSE 1052
            + L+ E  + F   V   D G P +S+SA   ++V +  +I    PRFTQ  Y    V  
Sbjct: 506  IALDHEAKSQFNFTVQVHDRGVPRLSASAPAPVVV-YITDINDTPPRFTQSSYTAKVVLP 682

Query: 1053 LAARGTVVGVISA---AAINQSIVYSIVAGNEEDKFGINNVTGVIYVNSPLDYETRTSYV 1109
                  VV V +        + + YSI  GNE   F IN  +GV++V    D+  + SY 
Sbjct: 683  TYHDVRVVKVEAEDPDTISTKPLTYSIAGGNEGSVFAINPQSGVLHVEH-TDH-IQNSYE 856

Query: 1110 LRVQA 1114
            L+VQA
Sbjct: 857  LKVQA 871

 Score = 39.7 bits (91), Expect = 0.012,   Method: Compositional matrix adjust.
 Identities = 24/93 (25%), Positives = 46/93 (49%)
 Frame = +1

Query: 327 ILYSILVGTPEDYPRFFHMHPRTAELTLLEPVNRDFHQKFDLVIKAEQDNGHPLPAFASL 386
           I+Y+I+ G  +D    F ++  +  ++    ++ + H  F+L I A   N     A   +
Sbjct: 100 IVYTIIAGNTDDC---FFLNXNSGVVSTTRAIDYEHHHFFNLTILAA--NIVSATAVTHM 264

Query: 387 HIEILDENNQSPYFTMPSYQGYILESAPVGATI 419
            + + DEN+  P FT  ++ G + ESA  G+ +
Sbjct: 265 LVHVGDENDNRPQFTAQAFFGNVSESAEAGSMV 363

 Score = 36.2 bits (82), Expect = 0.12,   Method: Compositional matrix adjust.
 Identities = 38/132 (28%), Positives = 59/132 (44%), Gaps = 1/132 (0%)
 Frame = +1

Query: 512 PTFPEISYDVYVYTDMSPGDSVIQLTAVDADEGSNGEISYEILVGGKGD-FVINKTTGLV 570
           P FP  S  V    + SP  +V  L AV A+  S   I Y I+ G   D F +N  +G+V
Sbjct: 4   PKFPS-SEIVTELKENSPAGTV--LDAVRAE--SQSTIVYTIIAGNTDDCFFLNXNSGVV 168

Query: 571 SIAPGVELIVGQTYALTVQASDNAPPAERRHSICTVYIEVLPPNNQSPPRFPQLMYSLEV 630
           S    ++      + LT+ A++        H +  V  E     N + P+F    +   V
Sbjct: 169 STTRAIDYEHHHFFNLTILAANIVSATAVTHMLVHVGDE-----NDNRPQFTAQAFFGNV 333

Query: 631 SEAMRIGAILLN 642
           SE+   G+++LN
Sbjct: 334 SESAEAGSMVLN 369

 Score = 35.8 bits (81), Expect = 0.16,   Method: Compositional matrix adjust.
 Identities = 22/80 (27%), Positives = 39/80 (48%)
 Frame = +1

Query: 618 PPRFPQLMYSLEVSEAMRIGAILLNLQATDREGDPITYAIENGDPQRVFNLSETTGILSL 677
           PP+FP      E+ E    G +L  ++A  +    I Y I  G+    F L+  +G++S 
Sbjct: 1   PPKFPSSEIVTELKENSPAGTVLDAVRAESQS--TIVYTIIAGNTDDCFFLNXNSGVVST 174

Query: 678 GKALDRESTDRYILIVTASD 697
            +A+D E    + L + A++
Sbjct: 175 TRAIDYEHHHFFNLTILAAN 234

 Score = 30.4 bits (67), Expect = 7.2,   Method: Compositional matrix adjust.
 Identities = 25/83 (30%), Positives = 37/83 (44%), Gaps = 5/83 (6%)
 Frame = +2

Query: 882 LRSLDYEAFPDQEASITFLVEAFD-----IYGTMPPGIATVTVIVKDMNDYPPVFSKRIY 936
           L +LD+EA    ++   F V+  D     +  + P   A V V + D+ND PP F++  Y
Sbjct: 503 LIALDHEA----KSQFNFTVQVHDRGVPRLSASAP---APVVVYITDINDTPPRFTQSSY 661

Query: 937 KGMVAPDAVKGTPITTVYAEDAD 959
              V         +  V AED D
Sbjct: 662 TAKVVLPTYHDVRVVKVEAEDPD 730
>27585
          Length = 389

 Score = 55.1 bits (131), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 37/87 (42%), Positives = 47/87 (54%)
 Frame = -3

Query: 775 SIYTAVKLNREARDHYELVVVATDGAVHPRHSTLTLYIKVLDIDDNSPVFTNSTYTVVVE 834
           +I T   L+ E +  Y LVV A DGAV  R ST T+ I VLD++DN P+F  S YT  V 
Sbjct: 387 AISTVQGLDYEIQSLYLLVVEAADGAVDRRSSTATVTIYVLDVEDNVPIFVRSLYTASVT 208

Query: 835 ENLPAGTSFLQIEAKDVDLGANVSYRI 861
           EN         + A+D D   NV Y +
Sbjct: 207 EN-SNNALVTTVTAEDPDSIKNVVYEL 130

 Score = 38.1 bits (87), Expect = 0.032,   Method: Compositional matrix adjust.
 Identities = 27/82 (32%), Positives = 41/82 (50%)
 Frame = -3

Query: 879 LSLLRSLDYEAFPDQEASITFLVEAFDIYGTMPPGIATVTVIVKDMNDYPPVFSKRIYKG 938
           +S ++ LDYE     ++    +VEA D         ATVT+ V D+ D  P+F + +Y  
Sbjct: 384 ISTVQGLDYEI----QSLYLLVVEAADGAVDRRSSTATVTIYVLDVEDNVPIFVRSLYTA 217

Query: 939 MVAPDAVKGTPITTVYAEDADP 960
            V  ++     +TTV AED D 
Sbjct: 216 SVTENS-NNALVTTVTAEDPDS 154

 Score = 36.6 bits (83), Expect = 0.12,   Method: Compositional matrix adjust.
 Identities = 33/99 (33%), Positives = 45/99 (45%), Gaps = 1/99 (1%)
 Frame = -3

Query: 675 LSLGKALDRESTDRYILIVTASDGRPD-GTSXXXXXXXXXXXXXXXPVFDPYLPRNLSVV 733
           +S  + LD E    Y+L+V A+DG  D  +S               P+F   L    SV 
Sbjct: 384 ISTVQGLDYEIQSLYLLVVEAADGAVDRRSSTATVTIYVLDVEDNVPIFVRSLY-TASVT 208

Query: 734 EEEANAFVGQVRATDPDAGINGQVHYSLGNFNNLFRITS 772
           E   NA V  V A DPD+ I   V+  +GN  + F I+S
Sbjct: 207 ENSNNALVTTVTAEDPDS-IKNVVYELIGNDASAFSISS 94

 Score = 26.9 bits (58), Expect(2) = 0.99,   Method: Compositional matrix adjust.
 Identities = 28/93 (30%), Positives = 47/93 (50%), Gaps = 2/93 (2%)
 Frame = -3

Query: 999  LNEEPTTIFKLVVVAFDDGEPVMSSSATVRILVLH-PGEIPRFTQEEYRPPPVSELAARG 1057
            L+ E  +++ LVV A D      SS+ATV I VL     +P F +  Y    V+E +   
Sbjct: 366  LDYEIQSLYLLVVEAADGAVDRRSSTATVTIYVLDVEDNVPIFVRSLY-TASVTENSNNA 190

Query: 1058 TVVGVISAAAIN-QSIVYSIVAGNEEDKFGINN 1089
             V  V +    + +++VY ++ GN+   F I++
Sbjct: 189  LVTTVTAEDPDSIKNVVYELI-GNDASAFSISS 94

 Score = 25.0 bits (53), Expect(2) = 0.99,   Method: Compositional matrix adjust.
 Identities = 12/23 (52%), Positives = 13/23 (56%)
 Frame = -1

Query: 1090 VTGVIYVNSPLDYETRTSYVLRV 1112
            V G  + N  LDYETRT Y   V
Sbjct: 98   VPGSNFTNGALDYETRTFYEFFV 30
>24587
          Length = 2023

 Score = 51.6 bits (122), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 50/177 (28%), Positives = 80/177 (45%), Gaps = 20/177 (11%)
 Frame = -3

Query: 765  NNLFRITSNGSIYTAVKLNREARDHYELVV-------VATDGAVHPRHSTLTLYIKVLDI 817
            N+ F +  NGSI     L+ E ++ Y+L V       V +   +    +   + I ++DI
Sbjct: 1574 NDAFLVHLNGSIENIRVLDYEEQEEYKLCVLVHSSPTVDSTSRIVDNDTVAHITISIVDI 1395

Query: 818  DDNSPVFTNSTYTVVVEENLPAGTSFLQIEAKDVD--LGANVSYRIRSP----------- 864
            +DN PVF  +TYT V+ E +P+    +Q+ A D D  L +   Y IR+            
Sbjct: 1394 NDNGPVFPANTYTAVL-ETIPSEDVVIQVLANDPDGPLNSRTVYDIRTIMYYPPNDRRPF 1218

Query: 865  EVKHLFALHPFTGELSLLRSLDYEAFPDQEASITFLVEAFDIYGTMPPGIATVTVIV 921
             +K  F ++P  G ++ +    YE F      I  L  AFD+   +    A V V+V
Sbjct: 1217 SMKGAFTINPLNGVITAILP-SYEDFAQGYFEIQVL--AFDVQNQLFNDSAVVMVVV 1056

 Score = 48.9 bits (115), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 61/215 (28%), Positives = 92/215 (42%), Gaps = 14/215 (6%)
 Frame = -3

Query: 1100 LDYETRTSYVLRVQADSLEVVLANLRVPSKSNTAKVYIEIQDENDHPPVFQKKFYIGGV- 1158
            LDYE +  Y L V   S   V +  R+      A + I I D ND+ PVF    Y   + 
Sbjct: 1523 LDYEEQEEYKLCVLVHSSPTVDSTSRIVDNDTVAHITISIVDINDNGPVFPANTYTAVLE 1344

Query: 1159 ---SEDARMFASVLRVKATDRDTGNYSAMAY--RLII--PPIK----EGKEGFVVETYTG 1207
               SED      V++V A D D    S   Y  R I+  PP        K  F +    G
Sbjct: 1343 TIPSEDV-----VIQVLANDPDGPLNSRTVYDIRTIMYYPPNDRRPFSMKGAFTINPLNG 1179

Query: 1208 LIKTAML--FHNMRRSYFKFQVIATDDYGKGLSGKADVLVSVVNQLDMQVIVSNVPPTLV 1265
            +I TA+L  + +  + YF+ QV+A D   +  +  A V+V V+ +  +  +V +  P+  
Sbjct: 1178 VI-TAILPSYEDFAQGYFEIQVLAFDVQNQLFNDSAVVMVVVIEKSQVLRVVLDKTPSEG 1002

Query: 1266 EKKIEDLTEILDRYVQEQIPGAKVVVESIGARRHG 1300
                EDL   L+   +   P  +   ES+   + G
Sbjct: 1001 LAMAEDLQRALNAVGE---PNTEFFFESVSEHKTG 906

 Score = 38.5 bits (88), Expect = 0.026,   Method: Compositional matrix adjust.
 Identities = 39/144 (27%), Positives = 59/144 (40%), Gaps = 22/144 (15%)
 Frame = -3

Query: 471  LQPVDREEQQTYTFLITAFDG--VQESEPVV-------VNIRVMDANDNTPTFPEISYDV 521
            ++ +D EEQ+ Y   +       V  +  +V       + I ++D NDN P FP  +Y  
Sbjct: 1532 IRVLDYEEQEEYKLCVLVHSSPTVDSTSRIVDNDTVAHITISIVDINDNGPVFPANTYTA 1353

Query: 522  YVYTDMSPGDSVIQLTAVDADEGSNGEISYEILV------------GGKGDFVINKTTGL 569
             + T +   D VIQ+ A D D   N    Y+I                KG F IN   G+
Sbjct: 1352 VLET-IPSEDVVIQVLANDPDGPLNSRTVYDIRTIMYYPPNDRRPFSMKGAFTINPLNGV 1176

Query: 570  V-SIAPGVELIVGQTYALTVQASD 592
            + +I P  E      + + V A D
Sbjct: 1175 ITAILPSYEDFAQGYFEIQVLAFD 1104

 Score = 33.1 bits (74), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 48/194 (24%), Positives = 80/194 (41%), Gaps = 24/194 (12%)
 Frame = -3

Query: 870  FALHPFTGELSLLRSLDYEAFPDQEASITFLVEAFDIYGTMP-----PGIATVTVIVKDM 924
            F +H   G +  +R LDYE    +E  +  LV +     +         +A +T+ + D+
Sbjct: 1565 FLVH-LNGSIENIRVLDYEE--QEEYKLCVLVHSSPTVDSTSRIVDNDTVAHITISIVDI 1395

Query: 925  NDYPPVFSKRIYKGMVAPDAVKGTPITTVYAEDA-------DPPGMPASRVRYRVDDVQF 977
            ND  PVF    Y  +          + T+ +ED        DP G   SR  Y +  + +
Sbjct: 1394 NDNGPVFPANTYTAV----------LETIPSEDVVIQVLANDPDGPLNSRTVYDIRTIMY 1245

Query: 978  PYPASIFDVEEDSGRVVTRVN-LNEEPTTI-----------FKLVVVAFDDGEPVMSSSA 1025
             YP +  D    S +    +N LN   T I           F++ V+AFD    + + SA
Sbjct: 1244 -YPPN--DRRPFSMKGAFTINPLNGVITAILPSYEDFAQGYFEIQVLAFDVQNQLFNDSA 1074

Query: 1026 TVRILVLHPGEIPR 1039
             V ++V+   ++ R
Sbjct: 1073 VVMVVVIEKSQVLR 1032
>18019
          Length = 571

 Score = 51.2 bits (121), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 55/171 (32%), Positives = 82/171 (47%), Gaps = 5/171 (2%)
 Frame = -1

Query: 533 VIQLTAVDADEGSNGEI-SYEILVGGKG--DFVINKTTGLVSIAPGVELIVGQTYALTVQ 589
           ++ ++AVD D    G+I SY +L  G+    F I+  +G+V++   +       Y   VQ
Sbjct: 565 LLTVSAVDPD----GDIPSYRLLNVGQCLEYFYISPDSGVVNLRKPLYTNNINQYVCIVQ 398

Query: 590 ASDNAPPAERRHSICTVYIEVLPPNNQSPPRFPQLMYSLEVSEAMRIGAILLNLQATDRE 649
           ASD    A  R +  TV I V+      PPRF    YS  VSE   +GA +  + A D +
Sbjct: 397 ASDQRSNA--RLTNATVTINVI---RSQPPRFQNTPYSFTVSERTSVGASVYRVTAFDAD 233

Query: 650 GDPI-TYAIENGDPQ-RVFNLSETTGILSLGKALDRESTDRYILIVTASDG 698
            D +  Y +    P    F L+ TTG++S    L  ++T  Y+L V A D 
Sbjct: 232 LDGVLVYEVVGVAPAPSYFQLNTTTGVISPRVDLKVDTTQNYLLRVRAYDS 80

 Score = 37.4 bits (85), Expect = 0.066,   Method: Compositional matrix adjust.
 Identities = 54/194 (27%), Positives = 83/194 (42%), Gaps = 1/194 (0%)
 Frame = -1

Query: 841  TSFLQIEAKDVDLGANVSYRIRS-PEVKHLFALHPFTGELSLLRSLDYEAFPDQEASITF 899
            +  L + A D D G   SYR+ +  +    F + P +G ++L + L    + +       
Sbjct: 571  SQLLTVSAVDPD-GDIPSYRLLNVGQCLEYFYISPDSGVVNLRKPL----YTNNINQYVC 407

Query: 900  LVEAFDIYGTMPPGIATVTVIVKDMNDYPPVFSKRIYKGMVAPDAVKGTPITTVYAEDAD 959
            +V+A D         ATVT+ V  +   PP F    Y   V+     G  +  V A DAD
Sbjct: 406  IVQASDQRSNARLTNATVTINV--IRSQPPRFQNTPYSFTVSERTSVGASVYRVTAFDAD 233

Query: 960  PPGMPASRVRYRVDDVQFPYPASIFDVEEDSGRVVTRVNLNEEPTTIFKLVVVAFDDGEP 1019
              G+    + Y V  V  P P S F +   +G +  RV+L  + T  + L V A+D   P
Sbjct: 232  LDGV----LVYEVVGVA-PAP-SYFQLNTTTGVISPRVDLKVDTTQNYLLRVRAYDSAFP 71

Query: 1020 VMSSSATVRILVLH 1033
               + A V I V+ 
Sbjct: 70   TQVTEADVSIFVVR 29

 Score = 33.9 bits (76), Expect = 0.70,   Method: Compositional matrix adjust.
 Identities = 38/132 (28%), Positives = 54/132 (40%)
 Frame = -1

Query: 1079 GNEEDKFGINNVTGVIYVNSPLDYETRTSYVLRVQADSLEVVLANLRVPSKSNTAKVYIE 1138
            G   + F I+  +GV+ +  PL       YV  VQA       +N R+ + + T  V   
Sbjct: 502  GQCLEYFYISPDSGVVNLRKPLYTNNINQYVCIVQASDQR---SNARLTNATVTINVI-- 338

Query: 1139 IQDENDHPPVFQKKFYIGGVSEDARMFASVLRVKATDRDTGNYSAMAYRLIIPPIKEGKE 1198
                   PP FQ   Y   VSE   + ASV RV A D D      + Y ++   +     
Sbjct: 337  ----RSQPPRFQNTPYSFTVSERTSVGASVYRVTAFDADLD--GVLVYEVV--GVAPAPS 182

Query: 1199 GFVVETYTGLIK 1210
             F + T TG+I 
Sbjct: 181  YFQLNTTTGVIS 146
>14137
          Length = 815

 Score = 50.4 bits (119), Expect = 6e-06,   Method: Compositional matrix adjust.
 Identities = 62/240 (25%), Positives = 108/240 (45%), Gaps = 25/240 (10%)
 Frame = -1

Query: 482 YTFLITAFDGVQ--ESEPVVVNIRVMDANDNTPTF--PEISY---------DVYVYTDMS 528
           +   I A D  Q   ++  ++ + V D N N P F  P+ S          ++ V  +  
Sbjct: 782 HNVTIMALDLGQIPHNDSTMLTVFVQDVNINEPKFVAPDESLVDTAANSLPNITVDEEQP 603

Query: 529 PGDSVIQLTAVDADEGSNGEISYEI---LVGGKGDFVINKTTGLVSIAPGVELIVGQTYA 585
            G  ++QL+A DAD G+NG++ Y +   L G    F ++  +G ++    ++      + 
Sbjct: 602 IGSLILQLSATDADTGNNGQVFYGLDPDLSGQFNSFSVDAVSGNLTNKQILDREQTDMFQ 423

Query: 586 LTVQASDNAPPAERRHSICTVYIEVLPPNNQSPPRF-PQLMYSLEVSEAMR---IGAILL 641
           ++++A D   P   R S    +   L   N + PRF P    +L V E ++   +G++ +
Sbjct: 422 ISLKAEDQGTPT--RLSTVIPFRVFLRDVNDNDPRFPPPATLTLSVGEELQNVVVGSVDI 249

Query: 642 NLQATDREGDP----ITYAI-ENGDPQRVFNLSETTGILSLGKALDRESTDRYILIVTAS 696
              A D + DP    I Y I   GD    F+L   +G +++    DR+ T    L+V AS
Sbjct: 248 ---AVDDDHDPENKIICYYIYGGGDKVNSFSLDRDSGEMTVSIQQDRDVTPTVSLVVKAS 78

 Score = 50.1 bits (118), Expect = 9e-06,   Method: Compositional matrix adjust.
 Identities = 39/117 (33%), Positives = 62/117 (52%), Gaps = 8/117 (6%)
 Frame = -1

Query: 729 NLSVVEEE-ANAFVGQVRATDPDAGINGQVHYSL-----GNFNNLFRITSNGSIYTAVKL 782
           N++V EE+   + + Q+ ATD D G NGQV Y L     G FN+      +G++     L
Sbjct: 629 NITVDEEQPIGSLILQLSATDADTGNNGQVFYGLDPDLSGQFNSFSVDAVSGNLTNKQIL 450

Query: 783 NREARDHYELVVVATDGAVHPRHSTLTLY-IKVLDIDDNSPVF-TNSTYTVVVEENL 837
           +RE  D +++ + A D     R ST+  + + + D++DN P F   +T T+ V E L
Sbjct: 449 DREQTDMFQISLKAEDQGTPTRLSTVIPFRVFLRDVNDNDPRFPPPATLTLSVGEEL 279

 Score = 42.0 bits (97), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 62/247 (25%), Positives = 105/247 (42%), Gaps = 23/247 (9%)
 Frame = -1

Query: 790  YELVVVATDGAVHPRHSTLTLYIKVLDIDDNSPVF-----------TNSTYTVVVEENLP 838
            + + ++A D    P + +  L + V D++ N P F            NS   + V+E  P
Sbjct: 782  HNVTIMALDLGQIPHNDSTMLTVFVQDVNINEPKFVAPDESLVDTAANSLPNITVDEEQP 603

Query: 839  AGTSFLQIEAKDVDLGAN--VSYRIRSPEVK---HLFALHPFTGELSLLRSLDYEAFPDQ 893
             G+  LQ+ A D D G N  V Y +  P++    + F++   +G L+  + LD E    Q
Sbjct: 602  IGSLILQLSATDADTGNNGQVFYGL-DPDLSGQFNSFSVDAVSGNLTNKQILDRE----Q 438

Query: 894  EASITFLVEAFDIYGTMPPGIATVT---VIVKDMND----YPPVFSKRIYKGMVAPDAVK 946
                   ++A D  GT P  ++TV    V ++D+ND    +PP  +  +  G    + V 
Sbjct: 437  TDMFQISLKAED-QGT-PTRLSTVIPFRVFLRDVNDNDPRFPPPATLTLSVGEELQNVVV 264

Query: 947  GTPITTVYAEDADPPGMPASRVRYRVDDVQFPYPASIFDVEEDSGRVVTRVNLNEEPTTI 1006
            G+ +     +D DP         Y   D       + F ++ DSG +   +  + + T  
Sbjct: 263  GS-VDIAVDDDHDPENKIICYYIYGGGD-----KVNSFSLDRDSGEMTVSIQQDRDVTPT 102

Query: 1007 FKLVVVA 1013
              LVV A
Sbjct: 101  VSLVVKA 81

 Score = 32.7 bits (73), Expect = 1.7,   Method: Compositional matrix adjust.
 Identities = 60/251 (23%), Positives = 99/251 (39%), Gaps = 16/251 (6%)
 Frame = -1

Query: 138 VRIVVRDRNDNSPTF--KHESYY---------ATVNELTPVGTTIFTGFSGDNGATDIDD 186
           + + V+D N N P F    ES            TV+E  P+G+ I         ATD D 
Sbjct: 722 LTVFVQDVNINEPKFVAPDESLVDTAANSLPNITVDEEQPIGSLILQL-----SATDADT 558

Query: 187 GPNGQIEYVIQYNPEDPTSNDTFEIPLMLTGNVVLRKRLNYEDKTRYYVIIQANDRAQNL 246
           G NGQ+ Y +  +P+     ++F +   ++GN+  ++ L+ E    + + ++A D+    
Sbjct: 557 GNNGQVFYGL--DPDLSGQFNSFSVD-AVSGNLTNKQILDREQTDMFQISLKAEDQG--- 396

Query: 247 NERRXXXXXXXXXXXXXXXXXPMFLPCVL-----VPNTRDCRPLTYQAAIPELRTPEELN 301
                                P  L  V+     + +  D  P     A   L   EEL 
Sbjct: 395 --------------------TPTRLSTVIPFRVFLRDVNDNDPRFPPPATLTLSVGEELQ 276

Query: 302 PILVTPPIQAIDQDRNIQPPSDRPGILYSILVGTPEDYPRFFHMHPRTAELTLLEPVNRD 361
            ++V     A+D D +   P ++  I Y I  G   D    F +   + E+T+    +RD
Sbjct: 275 NVVVGSVDIAVDDDHD---PENKI-ICYYIYGGG--DKVNSFSLDRDSGEMTVSIQQDRD 114

Query: 362 FHQKFDLVIKA 372
                 LV+KA
Sbjct: 113 VTPTVSLVVKA 81

 Score = 30.8 bits (68), Expect = 6.3,   Method: Compositional matrix adjust.
 Identities = 19/74 (25%), Positives = 34/74 (45%)
 Frame = -1

Query: 1158 VSEDARMFASVLRVKATDRDTGNYSAMAYRLIIPPIKEGKEGFVVETYTGLIKTAMLFHN 1217
            V E+  + + +L++ ATD DTGN   + Y L  P +      F V+  +G +    +   
Sbjct: 620  VDEEQPIGSLILQLSATDADTGNNGQVFYGL-DPDLSGQFNSFSVDAVSGNLTNKQILDR 444

Query: 1218 MRRSYFKFQVIATD 1231
             +   F+  + A D
Sbjct: 443  EQTDMFQISLKAED 402
>13573
          Length = 765

 Score = 50.1 bits (118), Expect = 8e-06,   Method: Compositional matrix adjust.
 Identities = 45/145 (31%), Positives = 63/145 (43%), Gaps = 13/145 (8%)
 Frame = -1

Query: 754 NGQVHYSL----GNFNNLFRITSNGSIYTAVKLNREARD------HYELVV-VATDGAVH 802
            G++ Y L       +N+F I   G I     L+ E+ D       Y LV+ V  D    
Sbjct: 450 KGKIRYELYDDASQRSNVFTIDDQGLISNLQVLDYESVDRSLQPLQYRLVLWVHEDLDXK 271

Query: 803 PRHSTLTLYIKVLDIDDNSPVFTNSTYTVVVEENLPAGTSFLQIEAKDVDLGAN--VSYR 860
              +  TL I V D++DN P F  S Y   V ENLP   S  ++ A D+D G N  + Y 
Sbjct: 270 TLSNNATLIITVQDMNDNKPEFETSQYLTTVRENLPVHASVAEVTALDLDSGVNAELEYS 91

Query: 861 IRSPEVKHLFALHPFTGELSLLRSL 885
           + S      F   P +   SL ++L
Sbjct: 90  VDS----EYFTWRPSSETPSLTQAL 28

 Score = 47.4 bits (111), Expect = 6e-05,   Method: Compositional matrix adjust.
 Identities = 50/180 (27%), Positives = 82/180 (45%), Gaps = 10/180 (5%)
 Frame = -1

Query: 1017 GEPVMSSSATVRILV-LHPGEIPRFTQEEY-----RPPPVSELAAR--GTVVGVISAAAI 1068
            G+P   +  TVR+LV + P   P+F ++ Y        P  +L     G  + + +    
Sbjct: 621  GDPSQLAVMTVRVLVGVRP---PQFYEDPYYGFMFENSPTMQLVTHEDGKQLKISTVKFQ 451

Query: 1069 NQSIVYSIV--AGNEEDKFGINNVTGVIYVNSPLDYETRTSYVLRVQADSLEVVLANLRV 1126
               I Y +   A    + F I++  G+I     LDYE+    +  +Q   +  V  +L  
Sbjct: 450  KGKIRYELYDDASQRSNVFTIDD-QGLISNLQVLDYESVDRSLQPLQYRLVLWVHEDLDX 274

Query: 1127 PSKSNTAKVYIEIQDENDHPPVFQKKFYIGGVSEDARMFASVLRVKATDRDTGNYSAMAY 1186
             + SN A + I +QD ND+ P F+   Y+  V E+  + ASV  V A D D+G  + + Y
Sbjct: 273  KTLSNNATLIITVQDMNDNKPEFETSQYLTTVRENLPVHASVAEVTALDLDSGVNAELEY 94

 Score = 39.7 bits (91), Expect = 0.012,   Method: Compositional matrix adjust.
 Identities = 21/57 (36%), Positives = 30/57 (52%)
 Frame = -1

Query: 140 IVVRDRNDNSPTFKHESYYATVNELTPVGTTIFTGFSGDNGATDIDDGPNGQIEYVI 196
           I V+D NDN P F+   Y  TV E  PV  ++      +  A D+D G N ++EY +
Sbjct: 243 ITVQDMNDNKPEFETSQYLTTVRENLPVHASV-----AEVTALDLDSGVNAELEYSV 88
>08534
          Length = 885

 Score = 48.9 bits (115), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 64/259 (24%), Positives = 116/259 (44%), Gaps = 18/259 (6%)
 Frame = -3

Query: 457 FTVTP-TGITRYLTLLQPVDREEQQTYTFLITAFDGVQES----EPVVVNIRVMDANDNT 511
           F + P TG+   +++ Q +  +   +Y   I A DG + S    E V +N+   D N  T
Sbjct: 772 FNINPNTGV---ISVTQSLFGDSASSYRLRIQASDGGKPSLVDYEVVTINV---DRNSFT 611

Query: 512 PTFPEISYDVYVYTD--MSPGDSVIQLTAVDADEGS----NGEISYEILVGGKGD--FVI 563
           P++   S   Y  T   +   D    L +V A +        +++Y ++  GK    F +
Sbjct: 610 PSWVNPSAPFYTSTTQVLETIDYSTILFSVSARDNDIIAPYNQVTYSLVNQGKAPTFFDV 431

Query: 564 NKTTGLVSIAPGVELIVGQTYALTVQASDNAPPAERRHSICTVYIEVLPPNNQSPPRFPQ 623
           N T+G + +   +     Q+Y++ + A+DN  P+E      TV + VL   N + P F  
Sbjct: 430 NPTSGEIRLRSSLLQDTDQSYSVLLTAADNGIPSEVALQTATVVVNVL--RNLNTPYFVG 257

Query: 624 LMYSLEVSEAMRIGAILLNLQATDRE----GDPITYAIENGDPQRV-FNLSETTGILSLG 678
             Y++ ++E   +G+ + +L A D +     + ++Y I   D   V F +   +GI+ +G
Sbjct: 256 SPYAITIAETTSVGSSIFSLTARDDDLANTFETLSYDIIGDDAATVYFTVESFSGIVRVG 77

Query: 679 KALDRESTDRYILIVTASD 697
             L   +   Y + V   D
Sbjct: 76  SDLSATTDSVYYVRVRVRD 20

 Score = 45.8 bits (107), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 74/290 (25%), Positives = 128/290 (44%), Gaps = 18/290 (6%)
 Frame = -3

Query: 842  SFLQIEAKDVDLGA---NVSYRIRSPEVK-HLFALHPFTGELSLLRSLDYEAFPDQEASI 897
            S   + A+D DL A    V++ I   +   + F ++P TG +S+ +SL    F D  +S 
Sbjct: 868  SIFTVSARDNDLQAPYNTVTFSIIGDDAAPNYFNINPNTGVISVTQSL----FGDSASSY 701

Query: 898  TFLVEAFDIYGTMPPGI-ATVTVIVKDMNDYPPVF---SKRIYKG--MVAPDAVKGTPIT 951
               ++A D  G  P  +   V  I  D N + P +   S   Y     V       T + 
Sbjct: 700  RLRIQASD--GGKPSLVDYEVVTINVDRNSFTPSWVNPSAPFYTSTTQVLETIDYSTILF 527

Query: 952  TVYAEDADPPGMPASRVRYRVDDVQFPYPASIFDVEEDSGRVVTRVNLNEEPTTIFKLVV 1011
            +V A D D    P ++V Y +  V      + FDV   SG +  R +L ++    + +++
Sbjct: 526  SVSARDNDIIA-PYNQVTYSL--VNQGKAPTFFDVNPTSGEIRLRSSLLQDTDQSYSVLL 356

Query: 1012 VAFDDGEP--VMSSSATVRILVLHPGEIPRFTQEEYRPPPVSELAARGTVVGVISA---- 1065
             A D+G P  V   +ATV + VL     P F    Y    ++E  + G+ +  ++A    
Sbjct: 355  TAADNGIPSEVALQTATVVVNVLRNLNTPYFVGSPY-AITIAETTSVGSSIFSLTARDDD 179

Query: 1066 -AAINQSIVYSIVAGNEED-KFGINNVTGVIYVNSPLDYETRTSYVLRVQ 1113
             A   +++ Y I+  +     F + + +G++ V S L   T + Y +RV+
Sbjct: 178  LANTFETLSYDIIGDDAATVYFTVESFSGIVRVGSDLSATTDSVYYVRVR 29

 Score = 45.8 bits (107), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 62/266 (23%), Positives = 104/266 (39%), Gaps = 14/266 (5%)
 Frame = -3

Query: 653 ITYAIENGDPQ-RVFNLSETTGILSLGKALDRESTDRYILIVTASD-GRPDGTSXXXXXX 710
           +T++I   D     FN++  TG++S+ ++L  +S   Y L + ASD G+P          
Sbjct: 814 VTFSIIGDDAAPNYFNINPNTGVISVTQSLFGDSASSYRLRIQASDGGKPSLVDYEVVTI 635

Query: 711 XXXXXXXXXPVFDPYLP------RNLSVVEEEANAFVGQVRATDPDAGINGQVHYSL--- 761
                       +P  P      + L  ++     F    R  D  A  N QV YSL   
Sbjct: 634 NVDRNSFTPSWVNPSAPFYTSTTQVLETIDYSTILFSVSARDNDIIAPYN-QVTYSLVNQ 458

Query: 762 GNFNNLFRIT-SNGSIYTAVKLNREARDHYELVVVATDGAVHPRHS--TLTLYIKVLDID 818
           G     F +  ++G I     L ++    Y +++ A D  +    +  T T+ + VL  +
Sbjct: 457 GKAPTFFDVNPTSGEIRLRSSLLQDTDQSYSVLLTAADNGIPSEVALQTATVVVNVLR-N 281

Query: 819 DNSPVFTNSTYTVVVEENLPAGTSFLQIEAKDVDLGANVSYRIRSPEVKHLFALHPFTGE 878
            N+P F  S Y + + E    G+S   + A+D DL                         
Sbjct: 280 LNTPYFVGSPYAITIAETTSVGSSIFSLTARDDDLA------------------------ 173

Query: 879 LSLLRSLDYEAFPDQEASITFLVEAF 904
            +   +L Y+   D  A++ F VE+F
Sbjct: 172 -NTFETLSYDIIGDDAATVYFTVESF 98
>38001
          Length = 884

 Score = 48.1 bits (113), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 31/96 (32%), Positives = 55/96 (57%), Gaps = 5/96 (5%)
 Frame = -3

Query: 812 IKVLDIDDNSPVFTNSTYTVVVEENLPAGTSFLQIEAKDVDLGANVSYRI-----RSPEV 866
           I V+D++DN P F + T T+ + E  P+  + L ++A+D+DL AN++Y I      + ++
Sbjct: 774 IFVMDVNDNDPQFIDLTTTLTLNELTPSDVAVLTVKAEDLDLNANLTYSIVPRPSLADDM 595

Query: 867 KHLFALHPFTGELSLLRSLDYEAFPDQEASITFLVE 902
              F ++  +GEL++   LDYE     E ++   VE
Sbjct: 594 SGYFEVNASSGELTVKDHLDYETM--AEGTLVLAVE 493

 Score = 30.8 bits (68), Expect = 5.3,   Method: Compositional matrix adjust.
 Identities = 33/113 (29%), Positives = 54/113 (47%), Gaps = 9/113 (7%)
 Frame = -3

Query: 1060 VGVISAAA----INQSIVYSIV-----AGNEEDKFGINNVTGVIYVNSPLDYETRTSYVL 1110
            V V++  A    +N ++ YSIV     A +    F +N  +G + V   LDYET      
Sbjct: 687  VAVLTVKAEDLDLNANLTYSIVPRPSLADDMSGYFEVNASSGELTVKDHLDYET------ 526

Query: 1111 RVQADSLEVVLANLRVPSKSNTAKVYIEIQDENDHPPVFQKKFYIGGVSEDAR 1163
             +   +L + + +   PS++ TA V + ++D +D  PVF    Y G  +  AR
Sbjct: 525  -MAEGTLVLAVEDSGSPSRTATATVAVVVEDGDDQGPVF---VYPGCWTHRAR 379
>15121
          Length = 2573

 Score = 47.8 bits (112), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 30/89 (33%), Positives = 50/89 (56%), Gaps = 5/89 (5%)
 Frame = +3

Query: 798 DGAVHPRHSTLTLYIKVLDIDDNSPVF---TNSTYTVVVEENLPAGTSFLQIEAKDVDLG 854
           D    PR ++  + IKV DI+DN+PV    TN+ ++VV+      G +  ++ A DVD G
Sbjct: 276 DKGAIPRSNSTQVTIKVSDINDNAPVILFPTNANHSVVISTVPEKGVTLGRVIAYDVDEG 455

Query: 855 --ANVSYRIRSPEVKHLFALHPFTGELSL 881
             +++ Y I   + + +F + P TGE+ L
Sbjct: 456 NASSLIYAIIGGDARGVFDIKPKTGEIYL 542

 Score = 35.0 bits (79), Expect = 0.26,   Method: Compositional matrix adjust.
 Identities = 23/71 (32%), Positives = 38/71 (53%), Gaps = 2/71 (2%)
 Frame = +2

Query: 522 YVYTDMSPGDSVIQLTAVDADEGSNGEISYEIL--VGGKGDFVINKTTGLVSIAPGVELI 579
           +V    SPG  V ++ AVD DEG NGE+ +     V G+  F ++ + G V +A  ++  
Sbjct: 62  FVSEGASPGHVVAKMAAVDEDEGDNGEVEFFFAGSVTGEVPFTVH-SNGTVVVAGVLDRE 238

Query: 580 VGQTYALTVQA 590
             +++  TV A
Sbjct: 239 ESESHVFTVLA 271
>33294
          Length = 816

 Score = 47.4 bits (111), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 58/197 (29%), Positives = 84/197 (42%), Gaps = 9/197 (4%)
 Frame = -2

Query: 858  SYRIRSPEVKHLFALHPFTGELSLLRSLDYEAFPDQEASITFLVEAFDIYGT---MPPGI 914
            +YR  +    +LF ++  TGE+SL R+L       Q  S T   E F I  T   +P   
Sbjct: 722  AYRSGTAGTDNLFYVNAITGEVSLSRAL-------QLDSATSFYELF-ITATDQGIPFRS 567

Query: 915  ATV-----TVIVKDMNDYPPVFSKRIYKGMVAPDAVKGTPITTVYAEDADPPGMPASRVR 969
            ATV       + ++ ND  P+F    Y   +      G+ +  V   DAD    P + V 
Sbjct: 566  ATVDAQVQITVTRNQND--PIFINTPYDVTIPESQALGSSVYRVTVTDADTTA-PFNVVS 396

Query: 970  YR-VDDVQFPYPASIFDVEEDSGRVVTRVNLNEEPTTIFKLVVVAFDDGEPVMSSSATVR 1028
             R + D Q    A+ F    D+G +  R +L  +  T ++L V A D G P  S++  V 
Sbjct: 395  LRAIGDDQ----ATTFFTLADNGTISVRTSLLLDTNTFYRLRVEARDGGSPARSATGLVS 228

Query: 1029 ILVLHPGEIPRFTQEEY 1045
            I V      P F Q  Y
Sbjct: 227  INVRRNLVAPVFVQSSY 177

 Score = 47.4 bits (111), Expect = 6e-05,   Method: Compositional matrix adjust.
 Identities = 60/204 (29%), Positives = 89/204 (43%), Gaps = 9/204 (4%)
 Frame = -2

Query: 765 NNLF---RITSNGSIYTAVKLNREARDHYELVVVATDGAVHPRHSTLTLYIKV-LDIDDN 820
           +NLF    IT   S+  A++L+  A   YEL + ATD  +  R +T+   +++ +  + N
Sbjct: 695 DNLFYVNAITGEVSLSRALQLD-SATSFYELFITATDQGIPFRSATVDAQVQITVTRNQN 519

Query: 821 SPVFTNSTYTVVVEENLPAGTSFLQIEAKDVDLGA---NVSYRIRSPEVKHLFALHPFTG 877
            P+F N+ Y V + E+   G+S  ++   D D  A    VS R    +    F      G
Sbjct: 518 DPIFINTPYDVTIPESQALGSSVYRVTVTDADTTAPFNVVSLRAIGDDQATTFFTLADNG 339

Query: 878 ELSLLRSLDYEAFPDQEASITFLVEAFDIYGTMPPGIAT--VTVIVKDMNDYPPVFSKRI 935
            +S+  SL      D        VEA D  G  P   AT  V++ V+  N   PVF +  
Sbjct: 338 TISVRTSL----LLDTNTFYRLRVEARD--GGSPARSATGLVSINVR-RNLVAPVFVQSS 180

Query: 936 YKGMVAPDAVKGTPITTVYAEDAD 959
           Y   +      G  I  V A DAD
Sbjct: 179 YDATILETQSLGVNILRVAATDAD 108

 Score = 45.8 bits (107), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 62/236 (26%), Positives = 107/236 (45%), Gaps = 15/236 (6%)
 Frame = -2

Query: 958  ADPPGMPA-SRVRYRVDDVQFPYPA------SIFDVEEDSGRV-VTRVNLNEEPTTIFKL 1009
            + PP +PA   VR   + +++ Y +      ++F V   +G V ++R    +  T+ ++L
Sbjct: 785  SSPPSLPAIPIVRAPHNVIRYAYRSGTAGTDNLFYVNAITGEVSLSRALQLDSATSFYEL 606

Query: 1010 VVVAFDDGEPVMSSS--ATVRILVLHPGEIPRFTQEEYRPPPVSELAARGTVVGVISAAA 1067
             + A D G P  S++  A V+I V      P F    Y    + E  A G+ V  ++   
Sbjct: 605  FITATDQGIPFRSATVDAQVQITVTRNQNDPIFINTPY-DVTIPESQALGSSVYRVTVTD 429

Query: 1068 INQSIVYSIVA-----GNEEDKFGINNVTGVIYVNSPLDYETRTSYVLRVQADSLEVVLA 1122
             + +  +++V+      ++   F      G I V + L  +T T Y LRV+A        
Sbjct: 428  ADTTAPFNVVSLRAIGDDQATTFFTLADNGTISVRTSLLLDTNTFYRLRVEAR------- 270

Query: 1123 NLRVPSKSNTAKVYIEIQDENDHPPVFQKKFYIGGVSEDARMFASVLRVKATDRDT 1178
            +   P++S T  V I ++  N   PVF +  Y   + E   +  ++LRV ATD DT
Sbjct: 269  DGGSPARSATGLVSINVR-RNLVAPVFVQSSYDATILETQSLGVNILRVAATDADT 105

 Score = 43.1 bits (100), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 37/144 (25%), Positives = 57/144 (39%), Gaps = 2/144 (1%)
 Frame = -2

Query: 508 NDNTPTFPEISYDVYVYTDMSPGDSVIQLTAVDADEGSNGEISYEILVGG--KGDFVINK 565
           N N P F    YDV +    + G SV ++T  DAD  +   +     +G      F    
Sbjct: 527 NQNDPIFINTPYDVTIPESQALGSSVYRVTVTDADTTAPFNVVSLRAIGDDQATTFFTLA 348

Query: 566 TTGLVSIAPGVELIVGQTYALTVQASDNAPPAERRHSICTVYIEVLPPNNQSPPRFPQLM 625
             G +S+   + L     Y L V+A D   PA     + ++ +      N   P F Q  
Sbjct: 347 DNGTISVRTSLLLDTNTFYRLRVEARDGGSPARSATGLVSINVR----RNLVAPVFVQSS 180

Query: 626 YSLEVSEAMRIGAILLNLQATDRE 649
           Y   + E   +G  +L + ATD +
Sbjct: 179 YDATILETQSLGVNILRVAATDAD 108
>29630
          Length = 806

 Score = 46.6 bits (109), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 37/105 (35%), Positives = 51/105 (48%), Gaps = 4/105 (3%)
 Frame = -2

Query: 859 YRIRSP---EVKHLFALHPFTGELSLLRSLDYEAFPDQEASITFLVEAFDIYGTMPPGIA 915
           +R+RS      ++ FA++P TG +  +R L Y A P       FLVEA D  G  P    
Sbjct: 670 FRLRSSGSNAYQNCFAINPETGSIYPIRDL-YRA-PCTNNQYNFLVEAID-RGRSPLTSQ 500

Query: 916 TVTVIVK-DMNDYPPVFSKRIYKGMVAPDAVKGTPITTVYAEDAD 959
             TV +    N  PP+FS R Y   V  +A+     T + A+DAD
Sbjct: 499 PATVRIDITRNQNPPIFSARQYTASVQENAIVNFAFTRISADDAD 365

 Score = 36.6 bits (83), Expect = 0.092,   Method: Compositional matrix adjust.
 Identities = 30/94 (31%), Positives = 41/94 (43%), Gaps = 4/94 (4%)
 Frame = -2

Query: 764 FNNLFRIT-SNGSIYTAVKLNRE--ARDHYELVVVATDGAVHPRHST-LTLYIKVLDIDD 819
           + N F I    GSIY    L R     + Y  +V A D    P  S   T+ I +   + 
Sbjct: 640 YQNCFAINPETGSIYPIRDLYRAPCTNNQYNFLVEAIDRGRSPLTSQPATVRIDITR-NQ 464

Query: 820 NSPVFTNSTYTVVVEENLPAGTSFLQIEAKDVDL 853
           N P+F+   YT  V+EN     +F +I A D D 
Sbjct: 463 NPPIFSARQYTASVQENAIVNFAFTRISADDADF 362
>29492
          Length = 440

 Score = 44.3 bits (103), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 29/80 (36%), Positives = 43/80 (53%), Gaps = 1/80 (1%)
 Frame = +1

Query: 374 QDNGHPL-PAFASLHIEILDENNQSPYFTMPSYQGYILESAPVGATISESLNLTTPLRIV 432
           +D G P     A++ + ILD NN++PYF  P+    I ESAP+G  ++          + 
Sbjct: 223 RDKGSPARTGTATVTVNILDINNKNPYFDPPTTSINISESAPIGTPVT---------TLT 375

Query: 433 ALDKDIEDTKDPELHLFLND 452
           A+DKDI    D +L +FL D
Sbjct: 376 AIDKDI----DSDLEVFLID 423

 Score = 31.2 bits (69), Expect = 4.4,   Method: Compositional matrix adjust.
 Identities = 19/47 (40%), Positives = 26/47 (55%)
 Frame = +1

Query: 913 GIATVTVIVKDMNDYPPVFSKRIYKGMVAPDAVKGTPITTVYAEDAD 959
           G ATVTV + D+N+  P F        ++  A  GTP+TT+ A D D
Sbjct: 250 GTATVTVNILDINNKNPYFDPPTTSINISESAPIGTPVTTLTAIDKD 390
>37203
          Length = 818

 Score = 42.0 bits (97), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 36/107 (33%), Positives = 50/107 (46%), Gaps = 2/107 (1%)
 Frame = +3

Query: 1085 FGINNVTGVIYVNSPLDYETRTSYVLRVQADSLEVVLANLRVPSKS--NTAKVYIEIQDE 1142
            FG N     I     LDYE  T  V       L + L   RV S    NT  V + I+D 
Sbjct: 465  FGQNTF---IVCKQILDYEVVTPKV-----QQLTLTLTQ-RVGSVDLVNTVPVSVAIEDT 617

Query: 1143 NDHPPVFQKKFYIGGVSEDARMFASVLRVKATDRDTGNYSAMAYRLI 1189
            ND+ P+F +  Y+  V E+  +  ++L V A D DTG  + + Y L+
Sbjct: 618  NDNRPLFDQSQYLYTVKENFLVGENILTVMARDADTGQNAQIDYTLL 758

 Score = 41.2 bits (95), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 21/67 (31%), Positives = 33/67 (49%)
 Frame = +3

Query: 806 STLTLYIKVLDIDDNSPVFTNSTYTVVVEENLPAGTSFLQIEAKDVDLGANVSYRIRSPE 865
           +T+ + + + D +DN P+F  S Y   V+EN   G + L + A+D D G N         
Sbjct: 582 NTVPVSVAIEDTNDNRPLFDQSQYLYTVKENFLVGENILTVMARDADTGQNAQIDYTLLN 761

Query: 866 VKHLFAL 872
             +LF L
Sbjct: 762 TDNLFQL 782

 Score = 41.2 bits (95), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 20/57 (35%), Positives = 32/57 (56%)
 Frame = +3

Query: 498 VVVNIRVMDANDNTPTFPEISYDVYVYTDMSPGDSVIQLTAVDADEGSNGEISYEIL 554
           V V++ + D NDN P F +  Y   V  +   G++++ + A DAD G N +I Y +L
Sbjct: 588 VPVSVAIEDTNDNRPLFDQSQYLYTVKENFLVGENILTVMARDADTGQNAQIDYTLL 758

 Score = 40.0 bits (92), Expect = 0.009,   Method: Compositional matrix adjust.
 Identities = 37/124 (29%), Positives = 56/124 (45%), Gaps = 8/124 (6%)
 Frame = +3

Query: 844 LQIEAKDVDLG-ANVSYRIRSPEVKHLFALHPFTGELSLL---RSLDYEAFPDQEASITF 899
           LQIE K    G   ++    S +   LFA     G+ + +   + LDYE    +   +T 
Sbjct: 366 LQIEWKTFQAGPVTLTLSTDSGQPSGLFATQRGFGQNTFIVCKQILDYEVVTPKVQQLTL 545

Query: 900 L----VEAFDIYGTMPPGIATVTVIVKDMNDYPPVFSKRIYKGMVAPDAVKGTPITTVYA 955
                V + D+  T+P     V+V ++D ND  P+F +  Y   V  + + G  I TV A
Sbjct: 546 TLTQRVGSVDLVNTVP-----VSVAIEDTNDNRPLFDQSQYLYTVKENFLVGENILTVMA 710

Query: 956 EDAD 959
            DAD
Sbjct: 711 RDAD 722
>26675
          Length = 927

 Score = 40.8 bits (94), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 80/316 (25%), Positives = 125/316 (39%), Gaps = 8/316 (2%)
 Frame = -2

Query: 846  IEAKDVDLGAN-VSYRIRSPEVKHLFALHPFTGELSLLRSLDYEAFPDQEASITFLVEAF 904
            I+  D+D   N +S  I     K +F+L      + L R  D  A  D   + T +++  
Sbjct: 905  IDDNDIDTEFNTMSVSIIGRNDKGVFSLGG-NNNIVLSRPADLAA--DTVNTYTLVLQVR 735

Query: 905  DIYGTMPPGIATVTVIVKDMNDYPPVFSKRIYKGMVAPDAVKGTPITTVYAEDADPPGMP 964
            D  G        V  I    N Y PV         +    V GT I    A +ADP  + 
Sbjct: 734  DNAGRAALSSTAVVTINVQRNIYNPVCVNPAETININFTTVPGTVIGRFQASEADPGQV- 558

Query: 965  ASRVRYRVDDVQFPYPASI-----FDVEEDSGRVVTRVNLNEEPTTIFKLVVVAFDDGEP 1019
                      V++    S+     F V+ DSG +     L+      F+L V A D+G P
Sbjct: 557  ----------VKYILAGSVTAKDYFAVDYDSGEITLIQALSSTGNPTFQLSVSAVDNGFP 408

Query: 1020 VMSSSATVRILV-LHPGEIPRFTQEEYRPPPVSELAARGTVVGVISAAAINQSIVYSIVA 1078
              SS     + V + PG +   T   Y    ++E  A  ++      AA +  + YSI+ 
Sbjct: 407  SKSSICGKDVQVNVDPGTL---TIGNY-DITINENTAVNSLAITTVQAAPSDGVRYSIIG 240

Query: 1079 -GNEEDKFGINNVTGVIYVNSPLDYETRTSYVLRVQADSLEVVLANLRVPSKSNTAKVYI 1137
              N+ D F ++  +G I +   L  + RT Y L V+A           V  +S T+ V +
Sbjct: 239  INNDMDWFTVDESSGRITLAQNLKTDQRTLYTLLVRATR------QFAVTRQSATSTVRV 78

Query: 1138 EIQDENDHPPVFQKKF 1153
             +Q  N + P+F   +
Sbjct: 77   TVQ-RNVNGPIFIGNY 33
>18725
          Length = 934

 Score = 37.4 bits (85), Expect = 0.055,   Method: Compositional matrix adjust.
 Identities = 42/154 (27%), Positives = 64/154 (41%), Gaps = 17/154 (11%)
 Frame = -1

Query: 474 VDRE-EQQTYTFLITA--------FDGVQESEPVVVNIRVMDANDNTPTFPEISYDVYVY 524
           +DRE  + TY + ITA              +   V ++ + DANDN PTF + +Y V + 
Sbjct: 454 IDREIPEVTYGYTITAKATELYSNGSKTNATTTAVFSVTIDDANDNPPTFSDDTYYVTI- 278

Query: 525 TDMSPGDSVIQ-----LTAVDADEGSNGEISYEILVGGKGDFVINKTTGLVSIAPGVELI 579
            +M   +  +Q     +   D DE SN +   EI        V     G    AP + + 
Sbjct: 277 KEMEQINGTVQIPNLRMGVTDLDEPSNAQYRMEI--------VSQTFNGAFGFAPNIVMS 122

Query: 580 VGQTYALTV---QASDNAPPAERRHSICTVYIEV 610
             Q++ LTV   Q  D   PA R   +    +E+
Sbjct: 121 GSQSFYLTVNNFQYMDYEVPAYRSQVVTLRVVEI 20

 Score = 37.0 bits (84), Expect = 0.075,   Method: Composition-based stats.
 Identities = 19/54 (35%), Positives = 30/54 (55%), Gaps = 2/54 (3%)
 Frame = -2

Query: 781 KLNREARDHYELVVVATDGAVHPRHSTLTLYIKVL--DIDDNSPVFTNSTYTVV 832
           KL+ E R  Y   + A DGA    H+T ++ +++L  D  D  PVFTN  + ++
Sbjct: 816 KLDYETRVDYRAKIRAVDGANTAVHNTASVGVRILIGDRQDTDPVFTNKNFNLI 655

 Score = 34.7 bits (78), Expect = 0.41,   Method: Compositional matrix adjust.
 Identities = 18/52 (34%), Positives = 29/52 (55%)
 Frame = -1

Query: 140 IVVRDRNDNSPTFKHESYYATVNELTPVGTTIFTGFSGDNGATDIDDGPNGQ 191
           + + D NDN PTF  ++YY T+ E+  +  T+    +   G TD+D+  N Q
Sbjct: 343 VTIDDANDNPPTFSDDTYYVTIKEMEQINGTVQIP-NLRMGVTDLDEPSNAQ 191

 Score = 30.4 bits (67), Expect = 6.8,   Method: Compositional matrix adjust.
 Identities = 30/113 (26%), Positives = 51/113 (45%), Gaps = 6/113 (5%)
 Frame = -1

Query: 1094 IYVNSPLDYET-RTSYVLRVQADSLEVVLANLRVPSKSNTAKVYIEIQDENDHPPVFQKK 1152
            ++ ++ +D E    +Y   + A + E+  +N    + + TA   + I D ND+PP F   
Sbjct: 472  LFASTDIDREIPEVTYGYTITAKATEL-YSNGSKTNATTTAVFSVTIDDANDNPPTFSDD 296

Query: 1153 FYIGGVSEDARMFASV----LRVKATDRDTGNYSAMAYRL-IIPPIKEGKEGF 1200
             Y   + E  ++  +V    LR+  TD D    S   YR+ I+     G  GF
Sbjct: 295  TYYVTIKEMEQINGTVQIPNLRMGVTDLDEP--SNAQYRMEIVSQTFNGAFGF 143
>07525
          Length = 2093

 Score = 37.4 bits (85), Expect = 0.059,   Method: Compositional matrix adjust.
 Identities = 27/80 (33%), Positives = 40/80 (50%), Gaps = 7/80 (8%)
 Frame = +3

Query: 621 FPQLMYSLEVSEAMRIGAILLNLQATDREGDPITYAIENGDP---QRVFNLSETTG---- 673
           F Q  Y L++ E  R G+ +  L   ++   P+T +I + DP    R F +    G    
Sbjct: 258 FNQPTYYLQLPENQRNGSYVQTLLVHNQGDLPVTCSIISQDPDVNNRFFTIYHPQGRKNC 437

Query: 674 ILSLGKALDRESTDRYILIV 693
           IL L + LDRE  DR++L V
Sbjct: 438 ILQLRRNLDREEYDRHVLRV 497
>33084
          Length = 694

 Score = 32.7 bits (73), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 38/156 (24%), Positives = 61/156 (39%), Gaps = 21/156 (13%)
 Frame = +3

Query: 750 DAGINGQVHYSLG---------NFNNLFRITSNGSIYTAVKLNREARDHYELVVVATDGA 800
           D  + G + YS+          N N    + +  + Y  ++        Y L +V  D  
Sbjct: 234 DVNLAGSLRYSVDGDYPAQYVFNLNQTTGVQAVITNYLNLRTETLGETEYRLRIVVYDSL 413

Query: 801 VHPRHSTLTLYIKVLDIDDNSPVFTNSTYTVVVEENLPAGTSFLQIEAKDVDLGANVSYR 860
              R ST    I V   ++N P +    Y   + E+ P  +S   + A D D G  ++YR
Sbjct: 414 RENRRSTRVCTITVRR-NENGPRWLAPPYIFPISEDKPYISSVGPVTATDDDPGDTITYR 590

Query: 861 I------------RSPEVKHLFALHPFTGELSLLRS 884
           I             SP +   F ++  TG L+L+RS
Sbjct: 591 IVTEFAERNNLNQNSPSI--YFQINRDTGMLNLIRS 692

 Score = 32.7 bits (73), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 45/149 (30%), Positives = 70/149 (46%), Gaps = 9/149 (6%)
 Frame = +3

Query: 1050 VSELAARGTVVGVISAAAIN--QSIVYSIVAGN--EEDKFGINNVTGVI-----YVNSPL 1100
            +SE    G+ +  +SA+ +N   S+ YS V G+   +  F +N  TGV      Y+N   
Sbjct: 183  ISENLPIGSSILTLSASDVNLAGSLRYS-VDGDYPAQYVFNLNQTTGVQAVITNYLNLRT 359

Query: 1101 DYETRTSYVLRVQADSLEVVLANLRVPSKSNTAKVYIEIQDENDHPPVFQKKFYIGGVSE 1160
            +    T Y LR+      VV  +LR   +S   +V       N++ P +    YI  +SE
Sbjct: 360  ETLGETEYRLRI------VVYDSLRENRRS--TRVCTITVRRNENGPRWLAPPYIFPISE 515

Query: 1161 DARMFASVLRVKATDRDTGNYSAMAYRLI 1189
            D    +SV  V ATD D G+   + YR++
Sbjct: 516  DKPYISSVGPVTATDDDPGD--TITYRIV 596

 Score = 31.6 bits (70), Expect = 3.2,   Method: Compositional matrix adjust.
 Identities = 18/47 (38%), Positives = 30/47 (63%), Gaps = 2/47 (4%)
 Frame = +3

Query: 630 VSEAMRIGAILLNLQATDRE-GDPITYAIENGDP-QRVFNLSETTGI 674
           +SE + IG+ +L L A+D      + Y+++   P Q VFNL++TTG+
Sbjct: 183 ISENLPIGSSILTLSASDVNLAGSLRYSVDGDYPAQYVFNLNQTTGV 323
>35745
          Length = 423

 Score = 32.3 bits (72), Expect = 1.8,   Method: Compositional matrix adjust.
 Identities = 18/32 (56%), Positives = 19/32 (59%)
 Frame = +1

Query: 1083 DKFGINNVTGVIYVNSPLDYETRTSYVLRVQA 1114
            D+F IN VTGVI      D E R SYVL V A
Sbjct: 88   DEFRINQVTGVIRAEIVYDLEQRGSYVLTVVA 183
>28153
          Length = 871

 Score = 32.0 bits (71), Expect = 2.4,   Method: Compositional matrix adjust.
 Identities = 48/188 (25%), Positives = 74/188 (39%), Gaps = 13/188 (6%)
 Frame = +2

Query: 638 AILLNLQATDREG----DPITYAIENGDPQRVFNLSETTGILSLGKALDRESTDRYILIV 693
            I     ATD +     + + +A+        F +  TTG +S+  A+  ++   Y L V
Sbjct: 242 GIFFTALATDNDNSVRFNTVRFALAGDGALSSFFIDSTTGAVSMTSAILNDAGTVYKLQV 421

Query: 694 TASDGRPDGTSXXXXXXXXXXXXXXXPVF---DPYLPRNLSVVEEEANAFVGQVRATDPD 750
             SDG     S               PV+    P   R +   E  AN+ + Q+ ATD D
Sbjct: 422 IVSDGYCLN-SDQDTLTVIVRRNLFAPVWTSPGPNFVRRIPETENIANSIL-QLSATDQD 595

Query: 751 AGINGQVHYSLGNF------NNLFRITSNGSIYTAVKLNREARDHYELVVVATDGAVHPR 804
               GQV      F       NLF IT  G ++    +    ++ + L V A DG V+  
Sbjct: 596 QP--GQVFAGTYGFALTSDHQNLFFITPTGQVFLRRSMVGLTQNTFVLDVTANDG-VYSI 766

Query: 805 HSTLTLYI 812
             T+T+ +
Sbjct: 767 SGTVTVNV 790
>17610
          Length = 446

 Score = 30.0 bits (66), Expect = 9.8,   Method: Compositional matrix adjust.
 Identities = 17/61 (27%), Positives = 33/61 (54%)
 Frame = -1

Query: 782 LNREARDHYELVVVATDGAVHPRHSTLTLYIKVLDIDDNSPVFTNSTYTVVVEENLPAGT 841
           L+ E    Y +    +DG +  +   LT  +K+L++++  PVF  +TY   + E+ P G+
Sbjct: 437 LDYEQVSEYSITCTVSDGYLSSQGDVLT--VKILNVNE-PPVFDQTTYYCTMPESGPTGS 267

Query: 842 S 842
           +
Sbjct: 266 A 264
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|115385968|ref|NP_848831.2| transportin 1 isoform 1
[Mus musculus]
         (898 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

30330                                                                 138   1e-32
03738                                                                  52   9e-07
14383                                                                  33   0.42 
14913                                                                  33   0.76 
>30330
          Length = 538

 Score =  138 bits (347), Expect = 1e-32,   Method: Compositional matrix adjust.
 Identities = 64/95 (67%), Positives = 75/95 (78%)
 Frame = +1

Query: 802 IRPWCTSLRNIRDNEEKDSAFRGICTMISVNPSGVIQDFIFFCDAVASWINPKDDLRDMF 861
           IR WC SLRNIRDNEEKDSAFRGIC MI++NP+GV+ DF+FFCDAVASW NP+ DL++MF
Sbjct: 1   IRNWCISLRNIRDNEEKDSAFRGICNMITLNPNGVLNDFLFFCDAVASWNNPRPDLKEMF 180

Query: 862 CKILHGFKNQVGDENWRRFSDQFPLPLKERLAAFY 896
            KIL GFK Q+ D  WR F DQ P  L++RL   Y
Sbjct: 181 HKILTGFKEQIDDHAWRSFWDQCPQMLRDRLNLQY 285
>03738
          Length = 1037

 Score = 52.0 bits (123), Expect = 9e-07,   Method: Compositional matrix adjust.
 Identities = 22/30 (73%), Positives = 24/30 (80%)
 Frame = +1

Query: 780 AITIGRLGYVCPQEVAPMLQQFIRPWCTSL 809
           AITIGRLG VCPQ+VAP L QFIR WC + 
Sbjct: 229 AITIGRLGLVCPQDVAPHLHQFIRQWCVTF 318
>14383
          Length = 710

 Score = 33.5 bits (75), Expect = 0.42,   Method: Compositional matrix adjust.
 Identities = 20/76 (26%), Positives = 39/76 (51%)
 Frame = +2

Query: 440 MIPYLPELIPHLIQCLSDKKALVRSITCWTLSRYAHWVVSQPPDTYLKPLMTELLKRILD 499
           + PY+ +++P L +   D    ++       S        +  DTYLK ++ +LLK + +
Sbjct: 50  LAPYMSQIVPRLYRYQFDPNPRIQQAMAGIWSALVT-DNKKTVDTYLKEILHDLLKNLTN 226

Query: 500 SNKRVQEAACSAFATL 515
           +  RV+E++C+A   L
Sbjct: 227 NQWRVRESSCNAVTDL 274
>14913
          Length = 1174

 Score = 32.7 bits (73), Expect = 0.76,   Method: Compositional matrix adjust.
 Identities = 64/270 (23%), Positives = 115/270 (42%), Gaps = 24/270 (8%)
 Frame = -1

Query: 67   SEDEPTRSLSGLILKNNVK------AHFQNFPNGVTDFIKSECLNNIGDSSPLIRATVGI 120
            SE+   R L+ ++++  V+      A  Q+   G+ D I    L    +    +R ++  
Sbjct: 1165 SENAQVRQLAAVLIRRKVQKAKQWNALAQDVRQGIRDNILQLLLR---EPERGVRTSIAS 995

Query: 121  LITTIASKGELQN--WPDLLPKLCSLLDSEDYNTCEGAFGALQKICEDSAEILDSDVLDR 178
            L+ T A K +L +  WP L   L +   S D+  CE     L  + +   E L    L  
Sbjct: 994  LVGT-AXKHDLPSNAWPQLFEFLLTYTKSADHAQCELGMFVLYTVAQMXTEQLKPH-LAS 821

Query: 179  PLNIMIPKFLQFFKHSSPKIRSHAVACVNQ--FIISRT-----QALMLHIDSFIENLFAL 231
             L +++ K      +  P    +A+  +++  F +  T     QA +  +   I+ L  +
Sbjct: 820  MLQLLVEKLNDTQHYMVP---YYAIRTMSELVFFVGDTEGKVIQAAVPQVMVVIQQLTGV 650

Query: 232  AGDEEAEVRKNVCRALVM---LLEVRMDRLLPHMHNIVEYMLQRTQDQD--ENVALEACE 286
              DEE         AL +   LLE  +  ++PH+   V++ LQ +   D  + + ++A  
Sbjct: 649  --DEE-----KASEALELFDELLETEVTIIVPHLKPFVQFCLQVSAKTDFTDELRVKAMS 491

Query: 287  FWLTLA---EQPICKDVLVRH-LPKLIPVL 312
            F  +L    ++ I K  LV   L  L+P+L
Sbjct: 490  FIASLTRLKKKAIMKSHLVDPILHMLLPIL 401
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|52138536|ref|NP_849261.2| golgi-specific brefeldin
A-resistance factor 1 [Mus musculus]
         (1861 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

20966                                                                 139   1e-32
19534                                                                 134   4e-31
30249                                                                  67   1e-10
>20966
          Length = 686

 Score =  139 bits (350), Expect = 1e-32,   Method: Compositional matrix adjust.
 Identities = 71/130 (54%), Positives = 90/130 (69%), Gaps = 5/130 (3%)
 Frame = -1

Query: 515 YEMKEMALEAVVQLWRIPSFVTELYINYDCDYYCSNLFEDLTKLLSKNAFPVSGQLYTTH 574
           Y+ +E+ALE++VQLWRIP  VTELY+NYDCD YCSNLFE+LTKLLSKNAFPVSG L+TTH
Sbjct: 680 YDQREIALESIVQLWRIPGLVTELYLNYDCDLYCSNLFEELTKLLSKNAFPVSG-LFTTH 504

Query: 575 LLSLDALLTVIDSTESHCQAKVLNTL-----NQQEKKETARPGFEAVDGNPETNKSERAT 629
           LLSLDALLTV+DS + HC  +VL+       +QQ +  +   G   +D    T  +  + 
Sbjct: 503 LLSLDALLTVVDSIDQHCHHRVLSATKSDGESQQLEVSSGVEGEVKIDAPGSTEPAVYSV 324

Query: 630 SDGKSTGVAL 639
               STG  +
Sbjct: 323 RGPPSTGFTM 294

 Score = 55.5 bits (132), Expect = 2e-07,   Method: Composition-based stats.
 Identities = 25/39 (64%), Positives = 29/39 (74%)
 Frame = -3

Query: 706 GTEQFNQKPKKGIQFLQEKGLLTIPMDNTEVAQWLRENP 744
           GTE FNQKP KGI FLQE+GLL  P D  +VA +L+ NP
Sbjct: 126 GTEYFNQKPAKGIAFLQEQGLLATPXDPGQVATFLKXNP 10
>19534
          Length = 603

 Score =  134 bits (336), Expect = 4e-31,   Method: Compositional matrix adjust.
 Identities = 67/118 (56%), Positives = 87/118 (73%), Gaps = 6/118 (5%)
 Frame = -3

Query: 364 ADHSDSASVHDMDYVNPRGVRFTQSS----QKEGTALVPYGLPCIRELFRFLISLTNPHD 419
            + +D+ S  + ++VNP+GVRF Q       +EG  L+PYGLPC+RELFRFLISLTNP D
Sbjct: 355 VNSADTNSTQEGEFVNPKGVRFMQQQQQQHMREGYPLIPYGLPCVRELFRFLISLTNPID 176

Query: 420 RHNSEVMIHMGLHLLTVALESAP--VAQCQTLLGLIKDEMCRHLFQLLSVERLNLYAA 475
           RHN++VMIHMGL LLTVALE+    ++   +LL L+KDE+CR L  LL  ERL+L+AA
Sbjct: 175 RHNTDVMIHMGLSLLTVALETGADHISCYNSLLYLVKDELCRSLSMLLQSERLSLFAA 2
>30249
          Length = 822

 Score = 66.6 bits (161), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 35/81 (43%), Positives = 50/81 (61%), Gaps = 3/81 (3%)
 Frame = -2

Query: 794 EAPVIHRLLEVFTEHWRSCNGSP---FANSDACFALAYAVIMLNTDQHNHNVRKQNAPMT 850
           EA  I RL+E F E +  CN      F   D  F LA+A+IMLNTD HN +V+ +   M 
Sbjct: 821 EAQKIERLMEAFAERYCQCNPDQVKNFKTFDTVFLLAFAIIMLNTDLHNSSVKPER-KMK 645

Query: 851 LEEFRKNLKGVNGGKDFEQDI 871
           LE+F +NL+G++ G+D + D+
Sbjct: 644 LEDFVRNLRGIDDGEDVDGDL 582
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6678197|ref|NP_033332.1| synaptotagmin I [Mus
musculus]
         (421 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

29179                                                                 136   1e-32
30040                                                                 107   1e-23
26525                                                                  55   3e-18
31935                                                                  63   2e-10
16549                                                                  59   4e-09
17357                                                                  50   2e-06
07591                                                                  33   0.18 
25445                                                                  26   0.49 
26304                                                                  30   2.2  
>29179
          Length = 1113

 Score =  136 bits (343), Expect = 1e-32,   Method: Compositional matrix adjust.
 Identities = 70/144 (48%), Positives = 97/144 (67%), Gaps = 1/144 (0%)
 Frame = -3

Query: 142 LGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFETKVHRKT 201
           LG++Q+ L YDFQN  L + II+A +LPA D+ GTSDPYVK+ LLPDKK K  TKV ++ 
Sbjct: 541 LGRIQFGLMYDFQNLTLTLRIIRAVDLPAKDVTGTSDPYVKILLLPDKKHKLLTKVKKRN 362

Query: 202 LNPVFNEQFTFK-VPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVTEEWR 260
           LNP +NE F F+  P+++L  KTL + V D+DRFS+ D IGE  +P+N +D       W+
Sbjct: 361 LNPHWNECFLFEGWPHNKLLEKTLYLQVIDYDRFSRDDPIGETYLPLNEIDLSQSPVSWK 182

Query: 261 DLQSAEKEEQEKLGDICFSLRYVP 284
            LQ   K+ + KLG++  S+ Y P
Sbjct: 181 YLQPC-KDTRGKLGELLLSMCYQP 113

 Score = 60.5 bits (145), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 38/111 (34%), Positives = 57/111 (51%), Gaps = 1/111 (0%)
 Frame = -3

Query: 272 KLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNGXXXXXXXXXXX 331
           KLG I F L Y      LT+ I+ A +L   DV G SDPYVKI L+ +            
Sbjct: 544 KLGRIQFGLMYDFQNLTLTLRIIRAVDLPAKDVTGTSDPYVKILLLPD--KKHKLLTKVK 371

Query: 332 XXXXXPYYNESFSFE-VPFEQIQKVQVVVTVLDYDKIGKNDAIGKVFVGYN 381
                P++NE F FE  P  ++ +  + + V+DYD+  ++D IG+ ++  N
Sbjct: 370 KRNLNPHWNECFLFEGWPHNKLLEKTLYLQVIDYDRFSRDDPIGETYLPLN 218

 Score = 47.0 bits (110), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 21/43 (48%), Positives = 27/43 (62%)
 Frame = -1

Query: 274 GDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHL 316
           G  C      P  G+LTV++++AK LK  D+ G SDPYVKI L
Sbjct: 144 GSCCCPCVISPNIGRLTVIVMKAKELKAKDITGSSDPYVKIWL 16

 Score = 34.3 bits (77), Expect = 0.092,   Method: Compositional matrix adjust.
 Identities = 15/29 (51%), Positives = 23/29 (79%)
 Frame = -1

Query: 157 QLLVGIIQAAELPALDMGGTSDPYVKVFL 185
           +L V +++A EL A D+ G+SDPYVK++L
Sbjct: 102 RLTVIVMKAKELKAKDITGSSDPYVKIWL 16
>30040
          Length = 652

 Score =  107 bits (267), Expect = 1e-23,   Method: Compositional matrix adjust.
 Identities = 50/133 (37%), Positives = 78/133 (58%)
 Frame = -3

Query: 276 ICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNGXXXXXXXXXXXXXXX 335
           +  SL Y+P A +LTVV+++AK+LK       +DP+V++ L+  G               
Sbjct: 650 VLISLSYLPAAERLTVVLMKAKDLKMSTSHPSADPFVRVSLLVEGKKVKRKKTSVRRASI 471

Query: 336 XPYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLA 395
            P +NE+ +F VP E + KV + V+VLD+D IG  D +G   +G    G EL HW++M+ 
Sbjct: 470 NPVWNEALAFNVPAEVLPKVTLEVSVLDHDLIGHGDVLGTCVLGAGCGGDELGHWNEMML 291

Query: 396 NPRRPIAQWHTLQ 408
           + R+ IA+WHTL+
Sbjct: 290 HQRKTIARWHTLK 252
>26525
          Length = 455

 Score = 55.1 bits (131), Expect(3) = 3e-18,   Method: Compositional matrix adjust.
 Identities = 33/65 (50%), Positives = 44/65 (67%), Gaps = 3/65 (4%)
 Frame = +1

Query: 167 ELPALD--MGGTSDPYVKVFLLPDKKKKFETKVHRKTLNPVFNEQFT-FKVPYSELGGKT 223
           +LP  D  +GG  DPYVK+ LLP+KK K +T+V RKTLNP ++E FT F V  +++G  T
Sbjct: 1   DLPPRDPSLGGC-DPYVKLQLLPEKKHKCKTRVVRKTLNPKYDETFTFFGVNANQMGSIT 177

Query: 224 LVMAV 228
           L  A 
Sbjct: 178 LHFAC 192

 Score = 38.5 bits (88), Expect(3) = 3e-18,   Method: Compositional matrix adjust.
 Identities = 26/72 (36%), Positives = 37/72 (51%), Gaps = 5/72 (6%)
 Frame = +3

Query: 228 VYDFDRFSKHDIIGEFKVPMNTVDFGH----VTEEWRDLQSAE-KEEQEKLGDICFSLRY 282
           V  FDRFS+ +IIGE   P++  D       +T   RD+     K   +  G++  SL Y
Sbjct: 189 VLSFDRFSRDEIIGEVIYPLSDTDVEKKEMTIT---RDITPRHLKYRNQGRGELLVSLCY 359

Query: 283 VPTAGKLTVVIL 294
            P A +L VV+L
Sbjct: 360 QPAANRLGVVVL 395

 Score = 35.8 bits (81), Expect(3) = 3e-18,   Method: Compositional matrix adjust.
 Identities = 14/20 (70%), Positives = 18/20 (90%)
 Frame = +2

Query: 295 EAKNLKKMDVGGLSDPYVKI 314
           +++NL KMD+ GLSDPYVKI
Sbjct: 395 QSRNLPKMDISGLSDPYVKI 454

 Score = 30.8 bits (68), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 12/23 (52%), Positives = 16/23 (69%)
 Frame = +2

Query: 161 GIIQAAELPALDMGGTSDPYVKV 183
           G  Q+  LP +D+ G SDPYVK+
Sbjct: 386 GRAQSRNLPKMDISGLSDPYVKI 454
>31935
          Length = 554

 Score = 62.8 bits (151), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 42/134 (31%), Positives = 65/134 (48%), Gaps = 6/134 (4%)
 Frame = -3

Query: 142 LGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKK--KFETKVHR 199
           LG++Q ++ Y  Q  +L V I +   +P  D     DPYVK+ LLP + K  K +T + +
Sbjct: 540 LGRIQLTITYSAQRQKLDVTIHKIMNIPLRDPSSIPDPYVKLHLLPGRSKESKRKTSIIK 361

Query: 200 KTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRF--SKHDIIGEFKVPMNTVDFGHVT- 256
              NPV++  F + +  SEL    L + V     F  S   IIG  K+P++  +      
Sbjct: 360 DNCNPVYDASFEYLISISELRHTELEVTVCTQKGFLSSGSPIIGMLKIPLDDSEITTPAG 181

Query: 257 -EEWRDLQSAEKEE 269
            + W DL+   K E
Sbjct: 180 LKSWFDLEPELKHE 139

 Score = 43.5 bits (101), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 31/127 (24%), Positives = 54/127 (42%), Gaps = 6/127 (4%)
 Frame = -3

Query: 273 LGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNGXXXXXXXXXXXX 332
           LG I  ++ Y     KL V I +  N+   D   + DPYVK+HL+               
Sbjct: 540 LGRIQLTITYSAQRQKLDVTIHKIMNIPLRDPSSIPDPYVKLHLLPGRSKESKRKTSIIK 361

Query: 333 XXXXPYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDA--IGKVFVGYN----STGAE 386
               P Y+ SF + +   +++  ++ VTV        + +  IG + +  +    +T A 
Sbjct: 360 DNCNPVYDASFEYLISISELRHTELEVTVCTQKGFLSSGSPIIGMLKIPLDDSEITTPAG 181

Query: 387 LRHWSDM 393
           L+ W D+
Sbjct: 180 LKSWFDL 160
>16549
          Length = 607

 Score = 58.9 bits (141), Expect = 4e-09,   Method: Compositional matrix adjust.
 Identities = 31/107 (28%), Positives = 60/107 (56%), Gaps = 2/107 (1%)
 Frame = +2

Query: 162 IIQAAELPALDMGGTSDPYVKVFLLPD--KKKKFETKVHRKTLNPVFNEQFTFKVPYSEL 219
           + ++AELP+        PYVK +LLPD  K+ K +TK+ + +++P FNE   +++  +E 
Sbjct: 38  LARSAELPS--------PYVKTYLLPDPEKQTKRKTKIVKHSVHPTFNEVLQYRMKETET 193

Query: 220 GGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVTEEWRDLQSAE 266
             +TL + V+D D   +++ +G   + +  ++    T +W  LQ  +
Sbjct: 194 RHRTLQVTVWDHDMLKENNFLGAVYLRLRDLELSDDTAKWYTLQKLQ 334

 Score = 37.0 bits (84), Expect = 0.016,   Method: Compositional matrix adjust.
 Identities = 28/120 (23%), Positives = 53/120 (44%)
 Frame = +2

Query: 289 LTVVILEAKNLKKMDVGGLSDPYVKIHLMQNGXXXXXXXXXXXXXXXXPYYNESFSFEVP 348
           L ++++  ++L +     L  PYVK +L+ +                 P +NE   + + 
Sbjct: 8   LHIMVMHVRDLAR--SAELPSPYVKTYLLPDPEKQTKRKTKIVKHSVHPTFNEVLQYRMK 181

Query: 349 FEQIQKVQVVVTVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQ 408
             + +   + VTV D+D + +N+ +G V++       EL   SD         A+W+TLQ
Sbjct: 182 ETETRHRTLQVTVWDHDMLKENNFLGAVYLRLR--DLEL---SD-------DTAKWYTLQ 325
>17357
          Length = 482

 Score = 50.1 bits (118), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 17/45 (37%), Positives = 31/45 (68%)
 Frame = +2

Query: 363 DYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTL 407
           D+D++ KN+ +G++ +G    G E  HW++++  PR+ IA+WH L
Sbjct: 2   DWDRMTKNEVVGRLEIGVKCGGQEANHWNEVINCPRKQIAEWHKL 136
>07591
          Length = 796

 Score = 33.5 bits (75), Expect = 0.18,   Method: Compositional matrix adjust.
 Identities = 21/85 (24%), Positives = 37/85 (43%), Gaps = 2/85 (2%)
 Frame = +2

Query: 294 LEAKNLKKMDVGGLSDPYVKIHLMQNGXXXXXXXXXXXXXXXXPYYNESFSFEVPFEQIQ 353
           +E + L   DV   SDP   ++L + G                P +  SF  +  FE++Q
Sbjct: 77  VECRGLLNKDVLSKSDPCAVLYLHRAGHYEEFGRTENVKNCLDPRFARSFVMDYYFEEVQ 256

Query: 354 KVQVVVTVLDYDK--IGKNDAIGKV 376
           K+ + V  +D     +  +D +GK+
Sbjct: 257 KLMICVYDIDNTTPDLSDDDFLGKI 331

 Score = 31.6 bits (70), Expect = 0.58,   Method: Compositional matrix adjust.
 Identities = 26/92 (28%), Positives = 39/92 (42%), Gaps = 7/92 (7%)
 Frame = +2

Query: 163 IQAAELPALDMGGTSDPYVKVFLLPDK---KKKFETKVHRKTLNPVFNEQFTFKVPYSEL 219
             A +L   D  G SDPY++V         +    T+V +  LNP +     F++    L
Sbjct: 473 FHAKKLDKKDFLGKSDPYLEVLRATSDGSWQMVHRTEVVKNNLNPSWRP---FELSMQTL 643

Query: 220 GG----KTLVMAVYDFDRFSKHDIIGEFKVPM 247
            G    + +   VYD+D    HD IG F   +
Sbjct: 644 CGGNHQQNIKFDVYDWDSDGSHDYIGGFTTTL 739
>25445
          Length = 460

 Score = 26.2 bits (56), Expect(2) = 0.49,   Method: Compositional matrix adjust.
 Identities = 14/33 (42%), Positives = 18/33 (54%), Gaps = 1/33 (3%)
 Frame = -3

Query: 168 LPALDMGGTSDPYVKVFLLP-DKKKKFETKVHR 199
           L  +D  G +DPY KV L+P D  K    K H+
Sbjct: 152 LCPMDPNGLADPYTKVKLIPYDSNKTNRNKDHQ 54

 Score = 24.3 bits (51), Expect(2) = 0.49,   Method: Compositional matrix adjust.
 Identities = 10/24 (41%), Positives = 15/24 (62%)
 Frame = -1

Query: 191 KKFETKVHRKTLNPVFNEQFTFKV 214
           K+ ETK  + +LNP ++E FT   
Sbjct: 79  KQTETKTIKSSLNPQWDETFTLTC 8
>26304
          Length = 1290

 Score = 29.6 bits (65), Expect = 2.2,   Method: Compositional matrix adjust.
 Identities = 21/70 (30%), Positives = 34/70 (48%), Gaps = 13/70 (18%)
 Frame = +3

Query: 163 IQAAELPALDMGG----TSDPYVKVFLLPDKK--------KKFETKVHRKTLNPVF-NEQ 209
           I  +EL A ++        DPYVK+ ++P K         ++  + V   T NPV+ NE 
Sbjct: 849 INISELEACNLKKGVFFNPDPYVKLTVVPSKSYPEKPHHHRELRSSVCPSTTNPVWDNET 1028

Query: 210 FTFKVPYSEL 219
           FT +   ++L
Sbjct: 1029FTLEAYVTDL 1058
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|70778976|ref|NP_032854.2| phosphoglycerate kinase 1
[Mus musculus]
         (417 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

31336                                                                 136   1e-32
05502                                                                  40   0.002
>31336
          Length = 655

 Score =  136 bits (343), Expect = 1e-32,   Method: Compositional matrix adjust.
 Identities = 85/181 (46%), Positives = 111/181 (61%), Gaps = 2/181 (1%)
 Frame = +1

Query: 178 GVNLPQKAGGFLMKKELNYFAKALESPERPFLAILGGAKVADKIQLINNMLDKVNEMIIG 237
           G+ LP +      K+  +   K   +PERPFLAILGGAKVADKIQLI N+LDKVNEMI G
Sbjct: 136 GIWLPTE------KRSFSTLPKPWTTPERPFLAILGGAKVADKIQLIENLLDKVNEMIXG 297

Query: 238 GGMAFTFLKVLNNMEIGTSLYDEEGAKIVKDLMSKAEKNGVK-ITLPVDFVTADKFDENA 296
           GGMAFTFLKVL  M+IG SL+DE G+KIVKDLM KA+K   + I L       +      
Sbjct: 298 GGMAFTFLKVLEEMKIGASLFDEAGSKIVKDLMEKAKKRMFRSIFLRTXSQATNLMKMLL 477

Query: 297 KTGQATVASGIPAGWMG-LDCGTESSKKYAEAVGRAKQIVWNGPVGVFEWEAFARGTKSL 355
                ++ + + A W   LD         ++  G++ ++  NGP GVFE+  FA+GTK++
Sbjct: 478 LVLLLSLLAFLMAAWAWMLDEKVSR*ISGSDWKGKSHRV--NGPPGVFEFANFAKGTKAV 651

Query: 356 M 356
           M
Sbjct: 652 M 654

 Score = 89.7 bits (221), Expect = 2e-18,   Method: Compositional matrix adjust.
 Identities = 43/69 (62%), Positives = 52/69 (75%)
 Frame = +2

Query: 140 VKAEPAKIDAFRASLSKLGDVYVNDAFGTAHRAHSSMVGVNLPQKAGGFLMKKELNYFAK 199
           +KA  A+++ FRASLSKLGDVY+NDAFGTAHRAHSSMVG  L QKA GFL+KK  +    
Sbjct: 2   IKASEAEVEKFRASLSKLGDVYINDAFGTAHRAHSSMVGCQLAQKASGFLLKKGASVLC- 178

Query: 200 ALESPERPF 208
             +SP +P 
Sbjct: 179 --QSPGQPL 199
>05502
          Length = 631

 Score = 40.0 bits (92), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 21/24 (87%), Positives = 22/24 (91%)
 Frame = -2

Query: 393 STGGGASLELLEGKVLPGVDALSN 416
           STGGGASLELLEGK LPGV ALS+
Sbjct: 630 STGGGASLELLEGKNLPGVAALSD 559
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|58037513|ref|NP_084293.1| retinol dehydrogenase 12
[Mus musculus]
         (316 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

26417                                                                 135   2e-32
27168                                                                  86   3e-17
03060                                                                  62   4e-10
07400                                                                  52   3e-07
05235                                                                  47   8e-06
11922                                                                  40   8e-04
03983                                                                  38   0.005
12758                                                                  37   0.011
05690                                                                  36   0.019
28229                                                                  35   0.041
18534                                                                  32   0.49 
18254                                                                  30   1.6  
30783                                                                  29   2.5  
37581                                                                  28   6.4  
>26417
          Length = 929

 Score =  135 bits (341), Expect = 2e-32,   Method: Compositional matrix adjust.
 Identities = 73/175 (41%), Positives = 107/175 (61%), Gaps = 4/175 (2%)
 Frame = +1

Query: 116 EKKLHILINNAGVMMCPYSKTTDGFETHFGVNHXXXXXXXXXXXXXXKESAPARVVNLSS 175
           E ++ ILINNAGV+  PY+ T DG ET+F  NH              K SAP+R++N+SS
Sbjct: 1   EDRVDILINNAGVIGLPYALTEDGLETNFATNHFGPFLLTNLLLDKLKSSAPSRIINVSS 180

Query: 176 IAHLIGKIRFHDLQGQKRYCSAFAYGHSKLANLLFTRELAKRLQGTG---VTAYAVHPGV 232
           +    GKI   +L+ +K +     Y +SKLAN+LFTRELA+RL  TG   VT + +HPG 
Sbjct: 181 VVQKAGKIDLDNLKAEKYFKEHKIYFNSKLANVLFTRELARRLVATGVTDVTVHCLHPGS 360

Query: 233 VLSEITRN-SYLLCLLWRLFSPFFKSTSQGAQTSLHCALAEDLEPLSGKYFSDCK 286
             +++  N  + +    +L   F  S  +GAQT+L CA+AE+++ +SGKYF+ C+
Sbjct: 361 XKTDLLNNMPWYVRYGMKLVRVFLLSPLEGAQTTLFCAMAEEVKDMSGKYFAQCQ 525
>27168
          Length = 665

 Score = 85.5 bits (210), Expect = 3e-17,   Method: Compositional matrix adjust.
 Identities = 51/140 (36%), Positives = 72/140 (51%), Gaps = 8/140 (5%)
 Frame = +3

Query: 17  LTAPSIRKFFAGGVCTTNVQI------PGKVVVITGANTGIGKETARELARRGARVYIAC 70
           L    +R+ F    C+T +Q+       G+V +ITGAN GIG ETAR LA  G  + +AC
Sbjct: 108 LNVAQVRQRFDS--CSTALQVLHGKDLHGRVALITGANCGIGFETARSLALHGCEIILAC 281

Query: 71  RDVLKGESAASEIRADTKNSQVLVR--KLDLSDTKSIRAFAERFLAEEKKLHILINNAGV 128
           R++   + A   I  +   ++   R   LDL     ++ F E+       +  LI NAGV
Sbjct: 282 RNLATAQEAIDRIAVERPAARARCRTASLDLGSLSDVKKFVEQIRQSVGHIDYLILNAGV 461

Query: 129 MMCPYSKTTDGFETHFGVNH 148
              PY+KT DG ET F V+H
Sbjct: 462 FALPYTKTVDGLETTFQVSH 521
>03060
          Length = 1893

 Score = 61.6 bits (148), Expect = 4e-10,   Method: Compositional matrix adjust.
 Identities = 63/253 (24%), Positives = 105/253 (41%), Gaps = 11/253 (4%)
 Frame = -1

Query: 32   TTNVQIPGKVVVITGANTGIGKETARELARRGARVYIACRDVLKGESAASEI---RADTK 88
            T    I GKVV++TGA++G+GK  A+   + G +V +A R V +  +    +     + K
Sbjct: 1710 TRAADIQGKVVLVTGASSGLGKACAKVFHQHGCQVILAGRSVERLNAVKDYLTKSEGEVK 1531

Query: 89   NSQVLVRKLDLSDTKSIRAFAERFLAEEKKLHILINNAGVMM--CPYSKTTDGFETHFGV 146
              +  V  +DL D  S++  AER +    K+ ++INNAG+    C    +    +    V
Sbjct: 1530 ACEPSVLAMDLEDLNSLQQLAERAVELFGKVDVVINNAGISYRGCIEDTSIQVDQKLMAV 1351

Query: 147  NHXXXXXXXXXXXXXXKESAPARVVNLSSIAHLIGKIRFHDLQGQKRYCSAFAYGHSKLA 206
            N+              +      +V +SS+            QG+       AY  SK A
Sbjct: 1350 NYFGHVALIKGLLPHMQARNSGHIVGISSV------------QGKISIPYRSAYSASKHA 1207

Query: 207  NLLFTRELAKRLQGTGVTAYAVHPGVVLSEITRNSYLLCLLWRLFSPFFKSTSQG----- 261
               F   L   L  T +    + PG + + ++ N+  +C     +    K+T  G     
Sbjct: 1206 LQAFFDCLRAELSCTKIKVSLLSPGYIKTNLSNNA--VCGDGTTYGVMDKTTEAGMTPEA 1033

Query: 262  -AQTSLHCALAED 273
             AQT LH  L ++
Sbjct: 1032 VAQTVLHAILKQE 994
>07400
          Length = 1577

 Score = 52.0 bits (123), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 44/135 (32%), Positives = 67/135 (49%), Gaps = 9/135 (6%)
 Frame = -3

Query: 2    LFILVLLTSFLSILYLTAPSIRKFFAGGVC-------TTNVQIPGKVVVITGANTGIGKE 54
            + +  + + ++S+L LTA  +      G C         +V    KVV+ITG +TGIG E
Sbjct: 1563 MVLYTMYSLWMSLLLLTAVVVAMV---GACRHVSRALDRDVPAKDKVVLITGCDTGIGHE 1393

Query: 55   TARELARRGARVYIACRDVLKGESAASEIRADTKNSQVLVRKLDLSDTKSIRAFAERF-- 112
             A E  +RG  V   C DV    S+ ++  A+ K   V+  +LD+S  +S+    +    
Sbjct: 1392 AALEANKRGLTVVAGCLDV---TSSGAQRLAEKKGVHVI--RLDVSSDESVANAMKSVSK 1228

Query: 113  LAEEKKLHILINNAG 127
            L E K L  +INNAG
Sbjct: 1227 LCEAKGLWAVINNAG 1183
>05235
          Length = 944

 Score = 47.4 bits (111), Expect = 8e-06,   Method: Compositional matrix adjust.
 Identities = 52/214 (24%), Positives = 87/214 (40%), Gaps = 7/214 (3%)
 Frame = -2

Query: 37  IPGKVVVITGANTGIGKETARELARRGARVYIACRDVLKGESAASEIRADTKNSQVLVRK 96
           I GK ++      GIG +T  E+ + G +  +   D ++  +A +E++A      +    
Sbjct: 877 IAGKNIIFVAGLGGIGLDTNHEIVKSGPK-NLVILDRIENPAAIAELKAINPKVTISYYP 701

Query: 97  LDL--SDTKSIRAFAERFLAEEKKLHILINNAGVMMCPYSKTTDGFETHFGVNHXXXXXX 154
            D+  S  +S++     F A+ KK+ +LIN AG++           E    VN       
Sbjct: 700 YDVTVSVAESVKLLKTVF-AQLKKVDLLINGAGIL------DDHQIERTIAVNFTGTVNT 542

Query: 155 XXXXXX--XXKESAPARVV-NLSSIAHLIGKIRFHDLQGQKRYCSAFAYGHSKLANLLFT 211
                     ++  P  V+ N+ S+             G         Y  SK   L FT
Sbjct: 541 TTAIMEFWDKRKGGPGGVIANICSVT------------GFNSIYQVPVYSASKAXALSFT 398

Query: 212 RELAKRLQGTGVTAYAVHPGVVLSEITR--NSYL 243
             LAK    TGVT Y+++PG+  + +    NS+L
Sbjct: 397 NSLAKLAHITGVTVYSINPGITHTPLVNKFNSWL 296
>11922
          Length = 2153

 Score = 40.4 bits (93), Expect = 8e-04,   Method: Compositional matrix adjust.
 Identities = 35/97 (36%), Positives = 51/97 (52%), Gaps = 9/97 (9%)
 Frame = +1

Query: 39  GKVVVITGANTGIGKETARELARRGARVYIACRDV-----LKGE--SAASEI-RADTKNS 90
           GK V ITGA+ GIGK  A +LA+ GA + IA +       L G   +AA E+  A  K  
Sbjct: 100 GKTVFITGASRGIGKAIAVKLAKDGANIVIAAKTAEAHPKLPGTIYTAAKEVEEAGGKAL 279

Query: 91  QVLVRKLDLSDTK-SIRAFAERFLAEEKKLHILINNA 126
             +V   +    K +++A A++F      + IL+NNA
Sbjct: 280 PCIVDIRNEDQVKVAVKAAADKF----GGIDILVNNA 378
>03983
          Length = 1099

 Score = 38.1 bits (87), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 52/205 (25%), Positives = 81/205 (39%), Gaps = 8/205 (3%)
 Frame = +2

Query: 37  IPGKVVVITGANTGIGKETARELARRGARVYIACRDVLKGESAASEIRADTKNSQVLVR- 95
           + G+ V+ITGA +G+GK  A      G  + +   D+    + A E        QV  + 
Sbjct: 170 VEGQRVLITGAGSGLGKLMAYRFMGLGCDLVL--WDI---NTEAIEAMERDMGQQVSCKA 334

Query: 96  -KLDLSDTKSIRAFAERFLAEEKKLHILINNAGVMM------CPYSKTTDGFETHFGVNH 148
             +DLS  + I   A++   E   + IL+NNAG++       CP S      E +   + 
Sbjct: 335 YTVDLSSREQIYKAADQVKREVGGVDILVNNAGIVTGRKFLDCPDSLIEKTMEVNSNAHF 514

Query: 149 XXXXXXXXXXXXXXKESAPARVVNLSSIAHLIGKIRFHDLQGQKRYCSAFAYGHSKLANL 208
                         K      +++++S A L G      + G   YC+      SK A +
Sbjct: 515 WTVKAFLPNMLAQNK----GHIISIASSAGLFG------VTGLADYCA------SKFAAV 646

Query: 209 LFTRELAKRLQGTGVTAYAVHPGVV 233
            F   L   L+  G T   VH  VV
Sbjct: 647 GFDESLRFELEAMGKT--GVHTTVV 715
>12758
          Length = 804

 Score = 37.0 bits (84), Expect = 0.011,   Method: Compositional matrix adjust.
 Identities = 34/144 (23%), Positives = 60/144 (41%), Gaps = 2/144 (1%)
 Frame = -1

Query: 98  DLSDTKSIRAFAERFLAEEKKLHILINNAGVMMCPYSKTT--DGFETHFGVNHXXXXXXX 155
           DL+     +   E  + +  +L+IL+N AG++     + T  D ++  F  N        
Sbjct: 717 DLTKEDDTKRVVEETVKQFGRLNILVNCAGIIELGNIENTSLDQYDRMFNTNVRSVYHLT 538

Query: 156 XXXXXXXKESAPARVVNLSSIAHLIGKIRFHDLQGQKRYCSAFAYGHSKLANLLFTRELA 215
                    +    +VN+SS+             G + + +  AY  +K A   FTR +A
Sbjct: 537 MLAVPHLVNTQ-GNIVNVSSV------------NGMRSFPNVLAYCMAKSAIDQFTRCVA 397

Query: 216 KRLQGTGVTAYAVHPGVVLSEITR 239
             L    V    V+PGV++SE+ +
Sbjct: 396 LELAPKKVRVNGVNPGVIISELQK 325
>05690
          Length = 1192

 Score = 36.2 bits (82), Expect = 0.019,   Method: Compositional matrix adjust.
 Identities = 29/94 (30%), Positives = 46/94 (48%), Gaps = 3/94 (3%)
 Frame = +2

Query: 39  GKVVVITGANTGIGKETARELARRGARVYIACRDVLKGESAASEIRADTKNSQVLVR-KL 97
           GK V ITG + G+G   A  L + G +V+  C  +  G      ++A  K SQ L    L
Sbjct: 173 GKAVFITGCDAGLGHLLAIHLDKLGVKVFAGC--LFPGGEGEQTLKA--KCSQRLCTVPL 340

Query: 98  DLSDTKSIRAFAERFLAE--EKKLHILINNAGVM 129
           D+   + +   A+    E   ++L  ++NNAG+M
Sbjct: 341 DVCSLEIVTTAADTVKRELDGQELWGVVNNAGIM 442
>28229
          Length = 633

 Score = 35.0 bits (79), Expect = 0.041,   Method: Compositional matrix adjust.
 Identities = 25/83 (30%), Positives = 45/83 (54%)
 Frame = -2

Query: 47  ANTGIGKETARELARRGARVYIACRDVLKGESAASEIRADTKNSQVLVRKLDLSDTKSIR 106
           A++GIG   A+ LAR GA + +  R+V   E+  + ++  T   QVL    D+  T    
Sbjct: 632 ASSGIGVAIAQVLAREGAVLSLVGRNVTNLEATRTTLQQQTTGVQVLNVVADV--TTDSA 459

Query: 107 AFAERFLAEEKKLHILINNAGVM 129
           A  ++ +    ++ +L+NNAG++
Sbjct: 458 AIIQQTINHYGRIDVLVNNAGIL 390

 Score = 29.3 bits (64), Expect = 2.1,   Method: Compositional matrix adjust.
 Identities = 23/68 (33%), Positives = 33/68 (48%)
 Frame = -1

Query: 170 VVNLSSIAHLIGKIRFHDLQGQKRYCSAFAYGHSKLANLLFTRELAKRLQGTGVTAYAVH 229
           VVN+SS A            G   +  A +YG SK A   FT+ ++  L   GV   +V+
Sbjct: 267 VVNVSSCA------------GICHFPGALSYGISKAALDQFTKIVSLELAPQGVRVNSVN 124

Query: 230 PGVVLSEI 237
           PG V++ I
Sbjct: 123 PGFVVTNI 100
>18534
          Length = 406

 Score = 31.6 bits (70), Expect = 0.49,   Method: Compositional matrix adjust.
 Identities = 22/104 (21%), Positives = 42/104 (40%), Gaps = 2/104 (1%)
 Frame = -2

Query: 97  LDLSDTKSIRAFAERFLAEEKKLHILINNAGVMMC-PYSKTTDG-FETHFGVNHXXXXXX 154
           +D+SD + I   A + + +   + +LINNAG++ C P+ +  D   +  + +N       
Sbjct: 387 VDISDREQIYQRAAQVIDDVGHVDVLINNAGIVCCKPFWELHDRVIQNTYNINIISHYWT 208

Query: 155 XXXXXXXXKESAPARVVNLSSIAHLIGKIRFHDLQGQKRYCSAF 198
                          +V + S+  ++G     D    K  C  F
Sbjct: 207 VKAFLPHMMRHNRGHIVTVGSVTGMLGTYGCSDYAATKYACIGF 76
>18254
          Length = 928

 Score = 29.6 bits (65), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 20/50 (40%), Positives = 26/50 (52%)
 Frame = +3

Query: 33  TNVQIPGKVVVITGANTGIGKETARELARRGARVYIACRDVLKGESAASE 82
           T+V + GKV V+ G    +GK  A+ L   GARV I   D +    AA E
Sbjct: 300 TDVMLAGKVAVVAGYGD-VGKGCAQALRAFGARVIITEIDPINALQAAME 446
>30783
          Length = 765

 Score = 28.9 bits (63), Expect = 2.5,   Method: Compositional matrix adjust.
 Identities = 18/40 (45%), Positives = 23/40 (57%)
 Frame = +1

Query: 200 YGHSKLANLLFTRELAKRLQGTGVTAYAVHPGVVLSEITR 239
           Y  SK A  +FT+ LA  L   GV   +V+PG V+S I R
Sbjct: 241 YCMSKAAMDMFTQCLALELAPHGVRVNSVNPGSVVSMIYR 360
>37581
          Length = 466

 Score = 27.7 bits (60), Expect = 6.4,   Method: Compositional matrix adjust.
 Identities = 11/23 (47%), Positives = 14/23 (60%)
 Frame = -2

Query: 246 LLWRLFSPFFKSTSQGAQTSLHC 268
           ++WR   P F  TS G+ TSL C
Sbjct: 279 MVWRP*GPIFSPTSGGSATSLDC 211
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|13928668|ref|NP_058558.1| vesicle transport through
interaction with t-SNAREs homolog 1A [Mus musculus]
         (217 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

04340                                                                 134   3e-32
>04340
          Length = 1396

 Score =  134 bits (337), Expect = 3e-32,   Method: Compositional matrix adjust.
 Identities = 74/151 (49%), Positives = 97/151 (64%)
 Frame = -3

Query: 42   EKQLEEARELLEQMDLEVREIPPQSRGMYSNRMRSYKQEMGKLETDFKRSRIAYSDEVRN 101
            +K  EEA ELLEQM+LEV+E   + R  Y  R+RSYK E+ K +TD KR+R+   D  R+
Sbjct: 1394 DKLFEEASELLEQMELEVKEQDAKDRQKYQTRIRSYKAELSKQQTDMKRARLGI-DANRD 1218

Query: 102  ELLGDAGNSSENQRAHLLDNTXXXXXXXXXXXAGYQIAVETEQIGQEMLENLSHDREKIQ 161
            ELLGD  + SE+QR  LLDNT            GY+IAVETE+IG +++E+L   R+ IQ
Sbjct: 1217 ELLGDDTHDSEDQRTRLLDNTERMERSSRRLEQGYRIAVETEEIGGQIMEDLHSQRQTIQ 1038

Query: 162  XXXXXXXXXXXNLGKSSRILTGMLRRIIQNR 192
                        LGKSSR+L+GM++RIIQNR
Sbjct: 1037 RSRSRLHDMDTTLGKSSRVLSGMMKRIIQNR 945
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|160298219|ref|NP_032211.3| glutathione S-transferase,
theta 1 [Mus musculus]
         (240 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

20209                                                                 134   3e-32
08076                                                                  79   1e-15
20405                                                                  44   4e-05
35754                                                                  37   0.005
16317                                                                  31   0.46 
13785                                                                  28   2.6  
>20209
          Length = 979

 Score =  134 bits (338), Expect = 3e-32,   Method: Compositional matrix adjust.
 Identities = 70/188 (37%), Positives = 108/188 (57%), Gaps = 1/188 (0%)
 Frame = -1

Query: 33  VELRKGEHLSDAFARVNPMKRVPAMMDGGFTLCESVAILLYLAHKYKVPDHWYPQDLQAR 92
           V LRKGEH S+ F +V+P + VPA+ D GF L ES+AI+ Y+A    V DHW P D + R
Sbjct: 976 VALRKGEHYSEDFVKVHPFRLVPALNDDGFRLTESIAIVDYIAKTRDVADHWLPADPKKR 797

Query: 93  ARVDEYLAWQHTGLRRSCLRALWHKVMFPVFLGEQIPPETLAATLAELDVNLQVLEDKFL 152
           A+V+EYL W H   R S      H ++ P   GE +  + +      +   ++ +E+ FL
Sbjct: 796 AKVNEYLHWHHANTRLSSAMLFQHLLLIPRMKGEPVDQKQVKTFTKRVQTAIKGIENYFL 617

Query: 153 QDKDFLVGPHISLADLVAITELMHPVG-GGCPVFEGHPRLAAWYQRVEAAVGKDLFREAH 211
           +D  F+    I++AD+ A+ ELM         ++E  P + AW +RV+  +G  LF +AH
Sbjct: 616 KDTPFISSDVITVADIFAVCELMQLYAVRQEELYESSPVVKAWVERVKKEIGP-LFDKAH 440

Query: 212 EVILKVKD 219
           +V+ +V+D
Sbjct: 439 QVVYRVRD 416
>08076
          Length = 914

 Score = 79.3 bits (194), Expect = 1e-15,   Method: Compositional matrix adjust.
 Identities = 43/135 (31%), Positives = 72/135 (53%), Gaps = 1/135 (0%)
 Frame = -2

Query: 86  PQDLQARARVDEYLAWQHTGLRRSCLRALWHKVMFPVFLGEQIPPETLAATLAELDVNLQ 145
           P D + RA+VDEYL W H   R S      H ++ P   GE +  + +      +   ++
Sbjct: 910 PADPKKRAKVDEYLHWHHANTRLSSAMLFQHLLLIPRMKGEPVDQKQVKTFTKRVQTAIK 731

Query: 146 VLEDKFLQDKDFLVGPHISLADLVAITELMHPVG-GGCPVFEGHPRLAAWYQRVEAAVGK 204
            +E+ FL+D  F+    I++AD+ A+ ELM         ++E  P + AW +RV+  +G 
Sbjct: 730 GIENYFLKDTPFISSNVITVADIFAVCELMQLYAVRQEELYESSPVVKAWVERVKKEIG- 554

Query: 205 DLFREAHEVILKVKD 219
            LF +AH+V+ +V+D
Sbjct: 553 PLFDKAHQVVYRVRD 509
>20405
          Length = 766

 Score = 44.3 bits (103), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 42/138 (30%), Positives = 63/138 (45%), Gaps = 3/138 (2%)
 Frame = -1

Query: 42  SDAFARVNPMKRVPAM--MDGGFTLCESVAILLYLAHKYKVPDHWYPQDLQARARVDEYL 99
           SD F +  P  +VPA    DG   L ES AI  Y+A+           D+  +A + ++ 
Sbjct: 652 SDGFLKKFPAGKVPAYESADGKVLLTESNAIAYYVANA-----TLRGSDVATQAAIYQWA 488

Query: 100 AWQHTGLR-RSCLRALWHKVMFPVFLGEQIPPETLAATLAELDVNLQVLEDKFLQDKDFL 158
           +W  + L   SC    W   +FP     Q   + +     +L   L+VL D  L  + FL
Sbjct: 487 SWADSELLPASCA---W---VFPYLGIMQFNKQNVERAKNDLLAALKVL-DGHLLTRTFL 329

Query: 159 VGPHISLADLVAITELMH 176
           V   I+LAD++  T L+H
Sbjct: 328 VTERITLADIIVFTTLIH 275
>35754
          Length = 581

 Score = 37.4 bits (85), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 41/152 (26%), Positives = 67/152 (44%), Gaps = 4/152 (2%)
 Frame = -2

Query: 53  RVPAMMDGGFTLCESVAILLYLAHKYKVPDHWYPQDLQARARVDEYLAWQHTGLRRSCLR 112
            +P  +DG   L +S AIL Y+A K+ +      +     ARV E +       R   +R
Sbjct: 484 NLPYYIDGDIKLTQSNAILRYIARKHNL----MGETPLESARV-EMMLENAMDFRNGVVR 320

Query: 113 ALWHKVMFPVFLGEQIP--PETLAATLAELDVNLQVLEDKFLQDKDFLVGPHISLADLVA 170
            +++   +   L E  P   ETLA              +K+L DK +  G  +++AD   
Sbjct: 319 MVYNP-KYTDLLEEYKPKVKETLAGF------------NKYLADKKWFAGDKVTVADF-H 182

Query: 171 ITELM--HPVGGGCPVFEGHPRLAAWYQRVEA 200
           + EL+  H +  G  V + +P+L A+    EA
Sbjct: 181 MYELLDQHRLMIGADVLKDYPKLTAFMAAFEA 86
>16317
          Length = 381

 Score = 30.8 bits (68), Expect = 0.46,   Method: Compositional matrix adjust.
 Identities = 11/25 (44%), Positives = 16/25 (64%)
 Frame = +3

Query: 170 AITELMHPVGGGCPVFEGHPRLAAW 194
           + T +  PVGGG   F+G+ R+ AW
Sbjct: 117 SSTSVQSPVGGGAAGFKGNQRVVAW 191
>13785
          Length = 923

 Score = 28.5 bits (62), Expect = 2.6,   Method: Compositional matrix adjust.
 Identities = 16/55 (29%), Positives = 27/55 (49%), Gaps = 2/55 (3%)
 Frame = +2

Query: 14  CRAIYIFAKKNNIPFQMHTVELRKGEHLSDAFARVNPMKRVPAMMDGG--FTLCE 66
           CR +++  + N   F+ HT+ L     +S A   +N    + ++ D G  F LCE
Sbjct: 194 CRXLHVIQQ*NGKHFKYHTIFLMLHNFMSSANCLMNQKPCLDSLADWGLLFMLCE 358
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|22003856|ref|NP_084290.1| hook homolog 1 [Mus
musculus]
         (728 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

33298                                                                 136   3e-32
09431                                                                  29   7.0  
>33298
          Length = 1182

 Score =  136 bits (343), Expect = 3e-32,   Method: Compositional matrix adjust.
 Identities = 95/287 (33%), Positives = 159/287 (55%), Gaps = 4/287 (1%)
 Frame = -2

Query: 438  DHLNQADASATKSYENLAAEIMPVEYREVFIRLQHENKMLRLQQEGTENERIXXXXXXXX 497
            D +     S+++  E L+   +P E +E  +RL+HENKML++   GT+NE          
Sbjct: 1175 DQMGDVGPSSSQRAEMLS---VPPEIKEQLLRLEHENKMLKMGTSGTQNEESQILQSQLD 1005

Query: 498  XKHRKMNELETEQRLSKERIGELQQQIEDLQKXXXXXXXXXXXXXXXXXXXXXXAHMEKL 557
              + + +EL+TE RL  +R+ E Q Q+EDLQ+                         +K+
Sbjct: 1004 DSNARNHELQTEVRLLNQRVLETQAQVEDLQEKQSSTESASSTEVLEMKKRVTE-QTQKM 828

Query: 558  TEVHEELQKKQELIEDLQPDISQNAQKISELEAALQKKDEDMKAMEERYKMYLEKARNVI 617
             E   +L ++   ++ ++ ++S + +K++ L+  L +KDE+M+AMEERYK YLEKA+ VI
Sbjct: 827  EEKELQLAQRXAQLDQVKTELSTSTEKMAALQDTLARKDEEMRAMEERYKRYLEKAKTVI 648

Query: 618  KTLDPKLNPA---SAEIMLLRKQLAEKERRIEILESEC-KVAKLRDYEEKLIVSAWYNKS 673
            K+LD  +N +   S E++ L+ QL EK++ I ++E E  K+  + D EE+LIV+AWYN  
Sbjct: 647  KSLD--MNQSLDTSPELVSLKHQLLEKDQYINLVEKEHEKMRSVHDEEERLIVTAWYNLG 474

Query: 674  LAFQKLGMESRLVSGASACKDSVAAAPARSFLAQQRHITNTRRNLSV 720
            +   +   E RL +              +SFLA+QR + +TRR+ ++
Sbjct: 473  MQLHRQAAEERLANNNM----------GQSFLARQRQVHSTRRSQTI 363
>09431
          Length = 1631

 Score = 28.9 bits (63), Expect = 7.0,   Method: Compositional matrix adjust.
 Identities = 10/27 (37%), Positives = 16/27 (59%)
 Frame = +1

Query: 87  SYYHEFLGQQISEELIPDLNQITECAD 113
           SY+H +  Q +S   IP ++ I +C D
Sbjct: 553 SYFHTYANQHVSHFCIPVISCIRQCID 633
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|39930477|ref|NP_149156.1| septin 8 [Mus musculus]
         (430 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

14132                                                                 135   3e-32
14677                                                                 121   8e-31
22078                                                                  69   3e-12
29788                                                                  67   1e-11
38061                                                                  55   6e-08
34156                                                                  42   3e-04
>14132
          Length = 422

 Score =  135 bits (340), Expect = 3e-32,   Method: Compositional matrix adjust.
 Identities = 65/139 (46%), Positives = 94/139 (67%), Gaps = 3/139 (2%)
 Frame = -2

Query: 107 FGDQINKDDSYRPIVDYIDAQFENYLQEELKIRRSLFDYHDTRIHVCLYFITPTGHSLKS 166
           FGD ++  + ++PI DYID+++E YL  E ++ R++    DTR+H CLYFI PTGH LK 
Sbjct: 421 FGDAVDNSNCWQPITDYIDSKYEEYLNAESRVNRTVMP--DTRVHCCLYFIAPTGHGLKP 248

Query: 167 LDLVTMKKLDSKVNIIPIIAKADTISKSELHKFKIKIMGELVSNGVQIYQFP-TDDEAVA 225
           LD+  MK+L  KVNIIP++AKADT++  E  +FK  I+ E+  + ++IY+FP  DDE   
Sbjct: 247 LDVEFMKRLHDKVNIIPLVAKADTLTPDECREFKKTILNEIAQHKIKIYEFPDCDDEEEM 68

Query: 226 EINAVMNA--HLPFAVVGS 242
           +I   +     +PFAVVGS
Sbjct: 67  KIQKRLRVSDRVPFAVVGS 11
>14677
          Length = 378

 Score =  121 bits (303), Expect(2) = 8e-31,   Method: Compositional matrix adjust.
 Identities = 54/76 (71%), Positives = 62/76 (81%)
 Frame = -1

Query: 81  VRLRPQTYDLQESNVHLKLTIVDAVGFGDQINKDDSYRPIVDYIDAQFENYLQEELKIRR 140
           V+L+  TYDL E NV LKLT VD  GFGDQINK DS++PIVDYIDAQF+ YLQEELKI+R
Sbjct: 228 VKLKAHTYDLTEKNVRLKLTTVDTTGFGDQINKADSWKPIVDYIDAQFDAYLQEELKIKR 49

Query: 141 SLFDYHDTRIHVCLYF 156
            L  YHD+R+H CLYF
Sbjct: 48  MLHSYHDSRVHACLYF 1

 Score = 30.4 bits (67), Expect(2) = 8e-31,   Method: Composition-based stats.
 Identities = 12/14 (85%), Positives = 13/14 (92%)
 Frame = -2

Query: 37  KSVTQGFSFNILCV 50
           KSV+QGF FNILCV
Sbjct: 362 KSVSQGFCFNILCV 321
>22078
          Length = 417

 Score = 68.9 bits (167), Expect = 3e-12,   Method: Compositional matrix adjust.
 Identities = 26/48 (54%), Positives = 38/48 (79%)
 Frame = +3

Query: 254 RARQYPWGVVQVENENHCDFVKLREMLIRVNMEDLREQTHSRHYELYR 301
           R R YPWG+V+V+N +HCDF++LR+MLI  +M+DL++ T   HYE +R
Sbjct: 3   RGRAYPWGIVEVDNXSHCDFIRLRQMLISTHMQDLKDVTSDVHYENFR 146
>29788
          Length = 687

 Score = 67.0 bits (162), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 36/94 (38%), Positives = 59/94 (62%), Gaps = 4/94 (4%)
 Frame = +3

Query: 259 PWGVVQVENENHCDFVKLREMLIRVNMEDLREQTHSRHYELYRRCKLEEMGFQDSDGDSQ 318
           PWG+V+VEN  H DF+ LR MLIR +M+DL++ T++ HYE +R  KL       ++G  +
Sbjct: 3   PWGIVEVENLEHNDFIALRNMLIRTHMQDLKDVTNNVHYENFRYNKL---APSTTEGKVK 173

Query: 319 PFSLQE----TYEAKRKEFLSELQRKEEEMRQMF 348
           P +L +        +R+E + ++++ E EM Q+F
Sbjct: 174 PGALAKDPLSQMAEERQEHMVKMKKMEAEMEQVF 275
>38061
          Length = 206

 Score = 55.1 bits (131), Expect = 6e-08,   Method: Composition-based stats.
 Identities = 22/30 (73%), Positives = 27/30 (90%)
 Frame = +3

Query: 231 MNAHLPFAVVGSTEEVKVGNKLVRARQYPW 260
           MN+HLPFAVVGS +EVK+GNK+V+ARQ  W
Sbjct: 117 MNSHLPFAVVGSNDEVKIGNKMVKARQGSW 206
>34156
          Length = 348

 Score = 42.4 bits (98), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 24/79 (30%), Positives = 40/79 (50%), Gaps = 5/79 (6%)
 Frame = -1

Query: 31  PDQLVSKSVTQGFSFNILCVGETGIGKSXXXXXXXXXXX-----XXXEASHHEECVRLRP 85
           P Q+  KSV +GF F ++ VGE+G+GKS                    +   ++ V++  
Sbjct: 237 PTQVHRKSVKKGFEFTLMVVGESGLGKSTLVNSLFLTDLYPERHIPSASEKIQQTVKIDA 58

Query: 86  QTYDLQESNVHLKLTIVDA 104
            T +++E  V L+LT+VD 
Sbjct: 57  STVEIEERGVKLRLTVVDT 1
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|9790087|ref|NP_062662.1| cAMP-regulated guanine
nucleotide exchange factor II [Mus musculus]
         (993 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

18885                                                                 137   3e-32
12552                                                                  83   5e-16
27710                                                                  54   3e-07
32091                                                                  50   5e-06
08195                                                                  44   2e-04
27853                                                                  37   0.045
20517                                                                  36   0.092
27148                                                                  34   0.30 
26155                                                                  33   0.44 
14517                                                                  32   1.0  
30704                                                                  32   1.4  
01730                                                                  30   7.1  
23619                                                                  29   7.9  
>18885
          Length = 838

 Score =  137 bits (344), Expect = 3e-32,   Method: Compositional matrix adjust.
 Identities = 63/104 (60%), Positives = 79/104 (75%), Gaps = 3/104 (2%)
 Frame = -3

Query: 22  RPLERSSEDVDIIFTRLKGVKAFEKFHPNLLRQICLCGYYENLEKGITLFRQGDIGTNWY 81
           RP ER++ED+DII+ +LK +K  EKFHP LL+Q+C  GYYE+LEKG+TLFRQGD+GTNWY
Sbjct: 320 RPSERTAEDLDIIYGKLKELKVLEKFHPLLLQQLCYYGYYESLEKGVTLFRQGDMGTNWY 141

Query: 82  AVLAGSLDVKVSETSS---HQDAVTICTLGIGTAFGESILDNTP 122
            VL GSL V VS+ +    HQD V +C +G GT+FGE IL   P
Sbjct: 140 TVLTGSLAVLVSDNARPKIHQDGVMLCVVGPGTSFGEGILTGKP 9

 Score = 56.6 bits (135), Expect = 5e-08,   Method: Compositional matrix adjust.
 Identities = 37/102 (36%), Positives = 55/102 (53%), Gaps = 9/102 (8%)
 Frame = -3

Query: 318 PGQRTVDDLEIIYDELLHIKALSHLSTTVKRELAGVLIFESHAKGGTVLFNQGEEGTSWY 377
           P +RT +DL+IIY +L  +K L      + ++L     +ES  KG T LF QG+ GT+WY
Sbjct: 317 PSERTAEDLDIIYGKLKELKVLEKFHPLLLQQLCYYGYYESLEKGVT-LFRQGDMGTNWY 141

Query: 378 IILKGSVNVV--------IYGKGV-VCTLHEGDDFGKLALVN 410
            +L GS+ V+        I+  GV +C +  G  FG+  L  
Sbjct: 140 TVLTGSLAVLVSDNARPKIHQDGVMLCVVGPGTSFGEGILTG 15
>12552
          Length = 1266

 Score = 83.2 bits (204), Expect = 5e-16,   Method: Compositional matrix adjust.
 Identities = 52/189 (27%), Positives = 82/189 (43%)
 Frame = -3

Query: 727  REQFDSLTPLPEQEGPTTGTVGTFELMSSKDLAYQMTTYDWELFNCVHELELIYHTFGRH 786
            +E  D  + LP  +      V     +S ++ A Q+   D  +F  +   EL    +   
Sbjct: 1045 QESLDKRSSLPRMKS-YDAVVFDVLRVSPEEFASQIXLMDLPVFKSIQPDELTSCAWTTK 869

Query: 787  NFKKTTANLDLFLRRFNEIQFWVVTEVCLCSQLSKRVQLLKKFIKIAAHCKEYKNLNSFF 846
                   N+  F RRFN + FWV  E+  C  L  R  +L  FIKIA    E  NL++  
Sbjct: 868  EKLIKAPNVVAFTRRFNHVNFWVQREILNCQTLKTRADVLAHFIKIAKKLLELNNLHAVM 689

Query: 847  AIVMGLSNVAVSRLALTWEKLPSKFKKFYAEFESLMDPSRNHRAYRLTAAKLEPPLIPFM 906
            A++  L + A+ RL+ TW  L  K K  Y     +     N +  R     ++ P IP++
Sbjct: 688  AVISALQSAAIFRLSGTWMMLSKKDKLMYERMADMFSECNNRQKLRDVMDNVKLPCIPYL 509

Query: 907  PLLIKDMTF 915
             L + D+ +
Sbjct: 508  GLYLTDLIY 482
>27710
          Length = 429

 Score = 53.9 bits (128), Expect = 3e-07,   Method: Composition-based stats.
 Identities = 30/92 (32%), Positives = 55/92 (59%)
 Frame = +2

Query: 366 LFNQGEEGTSWYIILKGSVNVVIYGKGVVCTLHEGDDFGKLALVNDAPRAASIVLREDNC 425
           +  QG+EG ++Y+I  G V+V +  + +V T+ EG  FG+LAL+   PRAA++  + D  
Sbjct: 8   IIQQGDEGDNFYVIDVGEVDVFVNSE-LVTTISEGGSFGELALIYGTPRAATVRAKSD-V 181

Query: 426 HFLRVDKEDFNRILRDVEANTVRLKEHDQDVL 457
               +D++ + RIL     +T+R ++  ++ L
Sbjct: 182 KLWGIDRDSYRRILM---GSTIRKRKMYEEFL 268

 Score = 40.0 bits (92), Expect = 0.005,   Method: Composition-based stats.
 Identities = 22/78 (28%), Positives = 44/78 (56%), Gaps = 1/78 (1%)
 Frame = +2

Query: 70  LFRQGDIGTNWYAVLAGSLDVKVSETSSHQDAVTICTLGIGTAFGE-SILDNTPRHATIV 128
           + +QGD G N+Y +  G +DV V       ++  + T+  G +FGE +++  TPR AT+ 
Sbjct: 8   IIQQGDEGDNFYVIDVGEVDVFV-------NSELVTTISEGGSFGELALIYGTPRAATVR 166

Query: 129 TRESSELLRIEQEDFKAL 146
            +   +L  I+++ ++ +
Sbjct: 167 AKSDVKLWGIDRDSYRRI 220
>32091
          Length = 348

 Score = 49.7 bits (117), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 33/117 (28%), Positives = 55/117 (47%), Gaps = 9/117 (7%)
 Frame = +3

Query: 738 EQEGPTTGTVGTFELMSSK---------DLAYQMTTYDWELFNCVHELELIYHTFGRHNF 788
           + + P    V + EL SS          D+A QMT  D +LF  +   E++   + +   
Sbjct: 3   QDQPPPVNPVQSIELSSSTPDLLSFKTLDIAEQMTLLDAQLFQKIEIPEVLL--WAKEQS 176

Query: 789 KKTTANLDLFLRRFNEIQFWVVTEVCLCSQLSKRVQLLKKFIKIAAHCKEYKNLNSF 845
           ++ + NL  F   FN++ +W  T +       +R + L KFIKI    ++ KN NS+
Sbjct: 177 EELSPNLTTFTEHFNKMSYWCRTRILTQEDPKEREKYLMKFIKIMRCLRKLKNFNSY 347
>08195
          Length = 2165

 Score = 44.3 bits (103), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 25/88 (28%), Positives = 49/88 (55%), Gaps = 3/88 (3%)
 Frame = -3

Query: 355  IFESHAKGGTVLFNQGEEGTSWYIILKGSVNVVIYGKGVVCTLHEGDD---FGKLALVND 411
            +FE   + G  + +QG++G ++Y+I  G+ ++ +  +G    +   D+   FG+LAL+ +
Sbjct: 1572 MFEKSVQPGEHIIDQGDDGDNFYVIDSGTYDIYVDVEGQAKLVGNYDNSGFFGELALMYN 1393

Query: 412  APRAASIVLREDNCHFLRVDKEDFNRIL 439
             PRAA+I+          +D+  F RI+
Sbjct: 1392 MPRAATIIASSTGT-IWALDRTTFRRIV 1312

 Score = 43.1 bits (100), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 29/130 (22%), Positives = 62/130 (47%), Gaps = 6/130 (4%)
 Frame = -3

Query: 38   LKGVKAFEKFHPNLLRQICLCGYYENLEKGITLFRQGDIGTNWYAVLAGSLDVKVSETSS 97
            +K +  F    P  ++++    + ++++ G  +  QGD G N+Y + +G+ D+ V     
Sbjct: 1635 VKNILLFRSLDPEQMQEVLDAMFEKSVQPGEHIIDQGDDGDNFYVIDSGTYDIYVDVEGQ 1456

Query: 98   HQDAVTICTLGIGTAFGE-SILDNTPRHATIVTRESSELLRIEQEDF-----KALWEKYR 151
             +        G    FGE +++ N PR ATI+   +  +  +++  F     K  ++K +
Sbjct: 1455 AKLVGNYDNSGF---FGELALMYNMPRAATIIASSTGTIWALDRTTFRRIVLKTAFQKRK 1285

Query: 152  QYMAGLLAPP 161
            +Y + L + P
Sbjct: 1284 KYESLLESVP 1255

 Score = 34.3 bits (77), Expect = 0.23,   Method: Compositional matrix adjust.
 Identities = 20/64 (31%), Positives = 29/64 (45%), Gaps = 9/64 (14%)
 Frame = -3

Query: 363  GTVLFNQGEEGTSWYIILKGSVNVVI---------YGKGVVCTLHEGDDFGKLALVNDAP 413
            G  +  QG+     Y +  G V + +          G+  V  L +G  FG+LAL+   P
Sbjct: 1182 GVQIIKQGDAADVMYFVESGQVRIAMTNKESTDPSAGETDVTVLEKGGYFGELALITHQP 1003

Query: 414  RAAS 417
            RAAS
Sbjct: 1002 RAAS 991
>27853
          Length = 864

 Score = 36.6 bits (83), Expect = 0.045,   Method: Compositional matrix adjust.
 Identities = 31/109 (28%), Positives = 49/109 (44%), Gaps = 1/109 (0%)
 Frame = +2

Query: 51  LLRQICLCGYYENLEKGITLFRQGDIGTNWYAVLAGSLDVKVSETSSHQDAVTICTLGIG 110
            +RQI     ++  E G  LFRQGD   + Y VL G L   ++     ++ V     G G
Sbjct: 194 FVRQIDFALDWQMTEAGKALFRQGDNSDSVYIVLTGRLRSVITLLGGKKEVV--GEYGRG 367

Query: 111 TAFG-ESILDNTPRHATIVTRESSELLRIEQEDFKALWEKYRQYMAGLL 158
              G   +L +T R  T +    +E+ +I +E    +  KY Q +  L+
Sbjct: 368 ELVGIVEVLTHTERATTNMAIRDTEVAKIPEELLTLIKLKYPQVVTRLI 514
>20517
          Length = 749

 Score = 35.8 bits (81), Expect = 0.092,   Method: Compositional matrix adjust.
 Identities = 25/79 (31%), Positives = 43/79 (54%), Gaps = 1/79 (1%)
 Frame = +3

Query: 79  NWYAVLAGSLDVKVSETSSHQDAVTICTLGIGTAFGE-SILDNTPRHATIVTRESSELLR 137
           ++Y +L+G++ V   E   +    T+ TL  G +FGE +++  + R AT+ T    ELL 
Sbjct: 18  SFYFILSGTVVVTQFE-RQYSTTRTLVTLDQGMSFGELAVITGSRRQATVSTMTEVELLC 194

Query: 138 IEQEDFKALWEKYRQYMAG 156
           I  +DF+ +      +MAG
Sbjct: 195 ISAKDFEDI------FMAG 233
>27148
          Length = 718

 Score = 33.9 bits (76), Expect = 0.30,   Method: Composition-based stats.
 Identities = 21/55 (38%), Positives = 33/55 (60%), Gaps = 3/55 (5%)
 Frame = -3

Query: 384 VNVVIYGKGVVCTL---HEGDDFGKLALVNDAPRAASIVLREDNCHFLRVDKEDF 435
           V+V+   +GV  T+   + GD FG+LA++N A R  S V+ +DN   L +  +DF
Sbjct: 338 VSVMDADRGVAKTVMYYNRGDSFGELAIMN-ATRRQSTVISKDNMQLLVLTDDDF 177
>26155
          Length = 693

 Score = 33.5 bits (75), Expect = 0.44,   Method: Compositional matrix adjust.
 Identities = 15/37 (40%), Positives = 23/37 (62%), Gaps = 1/37 (2%)
 Frame = -1

Query: 902 LIPFMPLLIKDMTFTHEG-NKTFIDNLVNFEKMRMIA 937
           +IPF  L +KD+ F +EG +    D  +NFEK  ++A
Sbjct: 633 VIPFFSLFVKDLYFLNEGCSNRHCDGNINFEKCWVLA 523
>14517
          Length = 475

 Score = 32.3 bits (72), Expect = 1.0,   Method: Composition-based stats.
 Identities = 17/40 (42%), Positives = 22/40 (55%)
 Frame = -2

Query: 835 HCKEYKNLNSFFAIVMGLSNVAVSRLALTWEKLPSKFKKF 874
           HCKE K+ N+FF  V G   VA+ +L L   + P K K  
Sbjct: 285 HCKETKHTNNFFKAVSG-QGVAIEKLQLVLIQEPPKVKSL 169
>30704
          Length = 643

 Score = 32.0 bits (71), Expect = 1.4,   Method: Composition-based stats.
 Identities = 14/29 (48%), Positives = 21/29 (72%)
 Frame = -2

Query: 383 SVNVVIYGKGVVCTLHEGDDFGKLALVND 411
           SV  V+  +G +C+++E + F KLALVND
Sbjct: 507 SVCSVLKDQGYICSINERNKFKKLALVND 421
>01730
          Length = 1734

 Score = 29.6 bits (65), Expect = 7.1,   Method: Compositional matrix adjust.
 Identities = 13/49 (26%), Positives = 26/49 (53%), Gaps = 2/49 (4%)
 Frame = +3

Query: 216  QCCVGTELVDWMIQQTSCVHSRTQAVG--MWQVLLEDGVLNHVDQERHF 262
            QCC+ +    W++ + SC+    Q  G  ++ V +  G++ HV+  + F
Sbjct: 1209 QCCIMSSFXYWLVAKKSCI*PLYQPTG*CLYVVWICQGLVRHVEDLKXF 1355
>23619
          Length = 640

 Score = 29.3 bits (64), Expect = 7.9,   Method: Composition-based stats.
 Identities = 17/43 (39%), Positives = 24/43 (55%), Gaps = 6/43 (13%)
 Frame = -3

Query: 807 FWVVTEVCLCSQ------LSKRVQLLKKFIKIAAHCKEYKNLN 843
           FW+ T VCLCS+      L K +  L+KF ++  +C    NLN
Sbjct: 359 FWIHTTVCLCSRKLMVQALLKLLFCLRKFAQLFRNC----NLN 243
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|170295840|ref|NP_035718.2| tripartite motif protein
28 [Mus musculus]
         (834 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

14625                                                                 136   4e-32
07490                                                                  48   1e-05
15283                                                                  46   5e-05
11830                                                                  43   5e-04
38359                                                                  42   7e-04
27297                                                                  42   0.001
26463                                                                  39   0.010
08137                                                                  37   0.038
26429                                                                  31   0.12 
26047                                                                  33   0.43 
15682                                                                  31   1.6  
34573                                                                  30   3.5  
04357                                                                  30   4.8  
01956                                                                  29   6.6  
>14625
          Length = 846

 Score =  136 bits (342), Expect = 4e-32,   Method: Compositional matrix adjust.
 Identities = 77/232 (33%), Positives = 121/232 (52%), Gaps = 6/232 (2%)
 Frame = +3

Query: 130 IVENYFMRDSGSKASSDSQDANQCCTSCEDNAPATSYCVECSEPLCETCVEAHQRVKYTK 189
           ++EN F+R   +  + D    +Q CT CE N PATS+CV+C + LC  CV AH+RV+ TK
Sbjct: 6   LIENIFIRKQAN-TTDDGDGTDQKCTGCESN-PATSFCVQCDDWLCADCVNAHKRVRMTK 179

Query: 190 DHTVRSTGPAKTRDG------ERTVYCNVHKHEPLVLFCESCDTLTCRDCQLNAHKDHQY 243
           DH + S   A T  G      E ++ C VH  E L LFCE C+ LTCRDCQL  H++H+Y
Sbjct: 180 DHQLTSLEEALTNQGGSSGPTEVSMLCRVHPKEKLTLFCEKCEVLTCRDCQLLQHQEHKY 359

Query: 244 QFLEDAVRNQRKLLASLVKRLGDKHATLQKNTKEVRSSIRQVSDVQKRVQVDVKMAILQI 303
           QFL++A  + +  L   +  + D+   L +   E+   + +V   +  +Q D+      I
Sbjct: 360 QFLQEAAESYKAKLTGSLSLMKDRREVLWRYQTEIEERLSKVKREKNDLQQDILRQADVI 539

Query: 304 MKELNKRGRVLVNDAQKVTEGQQERLERQHWTMTKIQKHQEHILRFASWALE 355
           +K +      +++     T+   +RL R+   +  +    +H + F    LE
Sbjct: 540 VKAVRTAVWAVLSSLHSFTDAAAKRLSREVGDVRDLVGKFDHCISFMDGILE 695
>07490
          Length = 1665

 Score = 48.1 bits (113), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 44/189 (23%), Positives = 75/189 (39%), Gaps = 3/189 (1%)
 Frame = -2

Query: 154  CTSCEDNAPATSYCVECSEPLCETCVEAHQRVKYTKDH---TVRSTGPAKTRDGERTVYC 210
            C+ C+ +  A SYC++C   +C  C + H +   T  H    VR+   AK   G+  V C
Sbjct: 1433 CSRCDGSVEAVSYCIQCEAKMCPGCQDTHDQT--TXGHPVEAVRTLTEAKLA-GKHVVKC 1263

Query: 211  NVHKHEPLVLFCESCDTLTCRDCQLNAHKDHQYQFLEDAVRNQRKLLASLVKRLGDKHAT 270
              H   P   +C S  TL C  C   A  DH       A+     L  S   RL +    
Sbjct: 1262 EKHPDRPANYYCRSHQTLACDQC---AQDDHSCCSGYLAISKLGPLARS---RLQETVDV 1101

Query: 271  LQKNTKEVRSSIRQVSDVQKRVQVDVKMAILQIMKELNKRGRVLVNDAQKVTEGQQERLE 330
            +++N   +   I+      +  + D+  A   +   L  + ++L++   ++ +     LE
Sbjct: 1100 MKQNAANLAYQIKLAKYSYRETERDINEAFDDLEDRLESQRQLLLDTLHEMKDASTGSLE 921

Query: 331  RQHWTMTKI 339
                T   +
Sbjct: 920  THKITQAAL 894
>15283
          Length = 402

 Score = 46.2 bits (108), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 16/43 (37%), Positives = 28/43 (65%)
 Frame = +1

Query: 627 ICRVCQKPGDLVMCNQCEFCFHLDCHLPALQDVPGEEWSCSLC 669
           +C  C++ G+L++C++C   +HL C  P L+ VP  +W C +C
Sbjct: 163 VCLKCRQDGELILCDKCPRSYHLHCVTPPLKKVPKGKWVCPVC 291
>11830
          Length = 629

 Score = 43.1 bits (100), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 21/49 (42%), Positives = 29/49 (59%), Gaps = 2/49 (4%)
 Frame = -1

Query: 628 CRVCQKPGDLVMCNQCEFCFHLDCHLPALQ--DVPGEEWSCSLCHVLPD 674
           C  C++ GDL+ C++C   FHL CH P L   ++P  EW C  C V P+
Sbjct: 152 CDSCKEGGDLLCCDRCPAAFHLLCHDPPLHEGELPPGEWVCHRCRVTPN 6
>38359
          Length = 1474

 Score = 42.4 bits (98), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 14/43 (32%), Positives = 24/43 (55%)
 Frame = -3

Query: 627 ICRVCQKPGDLVMCNQCEFCFHLDCHLPALQDVPGEEWSCSLC 669
           IC  C +P  +++C+ C+  +H+ C  P L  +P  +W C  C
Sbjct: 806 ICNKCTQPDMMLLCDSCDHGYHMACLRPPLMAIPEGDWFCPPC 678
>27297
          Length = 436

 Score = 41.6 bits (96), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 19/52 (36%), Positives = 27/52 (51%)
 Frame = +1

Query: 622 DDSATICRVCQKPGDLVMCNQCEFCFHLDCHLPALQDVPGEEWSCSLCHVLP 673
           DD    CRVC+  G+L+ C+ C   +H  C  P L+ +P  +W C  C   P
Sbjct: 151 DDHMEFCRVCKDGGELLCCDACPSAYHTHCLNPPLKIIPDGDWHCPRCDCPP 306

 Score = 37.4 bits (85), Expect = 0.027,   Method: Compositional matrix adjust.
 Identities = 16/40 (40%), Positives = 25/40 (62%)
 Frame = +1

Query: 630 VCQKPGDLVMCNQCEFCFHLDCHLPALQDVPGEEWSCSLC 669
           VCQ+ G++++C+ C   +HL C  P L + P  +WSC  C
Sbjct: 1   VCQQGGEIILCDTCPRAYHLVCLEPELDEAPEGKWSCPHC 120
>26463
          Length = 756

 Score = 38.5 bits (88), Expect = 0.010,   Method: Compositional matrix adjust.
 Identities = 28/110 (25%), Positives = 47/110 (42%), Gaps = 8/110 (7%)
 Frame = -2

Query: 158 EDNAPATSYCVECSEPLCETC------VEAHQRVKYTKDHTVRSTGPA--KTRDGERTVY 209
           +D   A  +C +C +PLC  C        ++Q    ++ H V    P+   T   E   +
Sbjct: 365 QDLPHAEYFCYQCQQPLCRHCHCFLHPASSNQ----SRHHIVTPLVPSDWTTLVHEHMTF 198

Query: 210 CNVHKHEPLVLFCESCDTLTCRDCQLNAHKDHQYQFLEDAVRNQRKLLAS 259
           C++H++E L ++C +C    C  C    H  H+       + N R  L S
Sbjct: 197 CHLHENELLSVYCVTCMVTYCDTCVEKEHAGHKLWEFRVNLENARNTLVS 48
>08137
          Length = 1776

 Score = 36.6 bits (83), Expect = 0.038,   Method: Compositional matrix adjust.
 Identities = 14/46 (30%), Positives = 26/46 (56%), Gaps = 3/46 (6%)
 Frame = -3

Query: 628 CRVCQKPGD---LVMCNQCEFCFHLDCHLPALQDVPGEEWSCSLCH 670
           CR+C++  D   +++C++C+   H+ C  P +  VP  +W C  C 
Sbjct: 364 CRICRRKADPEKMLLCDKCDRGHHMYCLTPPMTKVPTGDWFCPNCR 227
>26429
          Length = 403

 Score = 31.2 bits (69), Expect(2) = 0.12,   Method: Compositional matrix adjust.
 Identities = 13/27 (48%), Positives = 15/27 (55%)
 Frame = +3

Query: 628 CRVCQKPGDLVMCNQCEFCFHLDCHLP 654
           CR C K GDL+ C  C   +HL C  P
Sbjct: 201 CRCCHKLGDLLCCETCSAVYHLACVEP 281

 Score = 22.7 bits (47), Expect(2) = 0.12,   Method: Compositional matrix adjust.
 Identities = 7/14 (50%), Positives = 11/14 (78%)
 Frame = +2

Query: 656 LQDVPGEEWSCSLC 669
           ++ VP E+W CS+C
Sbjct: 284 MEQVPDEDWLCSVC 325
>26047
          Length = 430

 Score = 33.1 bits (74), Expect = 0.43,   Method: Compositional matrix adjust.
 Identities = 18/48 (37%), Positives = 26/48 (54%), Gaps = 4/48 (8%)
 Frame = -3

Query: 628 CRVC---QKPGDLVMCNQCEFCFHLDCHLPALQDVPG-EEWSCSLCHV 671
           C VC     PG  +MC++C+  +HL C  P L  +P  ++W C  C V
Sbjct: 311 CCVCGGKNDPGMQLMCDECDNAYHLACLNPPLSAIPDVDDWYCPDCKV 168
>15682
          Length = 1132

 Score = 31.2 bits (69), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 14/25 (56%), Positives = 16/25 (64%)
 Frame = -3

Query: 665 SCSLCHVLPDLKEEDGSLSLDGADS 689
           SC LC  +P LK  DGS SL  A+S
Sbjct: 341 SCBLCRTIPTLKPADGSFSLFSAES 267
>34573
          Length = 1514

 Score = 30.0 bits (66), Expect = 3.5,   Method: Compositional matrix adjust.
 Identities = 11/34 (32%), Positives = 20/34 (58%)
 Frame = +1

Query: 287 DVQKRVQVDVKMAILQIMKELNKRGRVLVNDAQK 320
           D+Q+++ + V+ A+  + KE+NK  R    D  K
Sbjct: 349 DIQRKINLSVRQAVCSLEKEMNKGPRTSTADNHK 450
>04357
          Length = 1093

 Score = 29.6 bits (65), Expect = 4.8,   Method: Composition-based stats.
 Identities = 14/29 (48%), Positives = 18/29 (62%), Gaps = 3/29 (10%)
 Frame = +1

Query: 151 NQCCT-SCEDNAPA--TSYCVECSEPLCE 176
           N CCT  C D  P+  T+ C+ECS+  CE
Sbjct: 871 NLCCTCGCCDVGPSILTALCLECSQVFCE 957
>01956
          Length = 1700

 Score = 29.3 bits (64), Expect = 6.6,   Method: Compositional matrix adjust.
 Identities = 16/56 (28%), Positives = 27/56 (48%), Gaps = 3/56 (5%)
 Frame = +3

Query: 617 GPGILDDSA-TICR--VCQKPGDLVMCNQCEFCFHLDCHLPALQDVPGEEWSCSLC 669
           GP I +D+  +IC    CQ    ++ C+ C    H +C+   +  +P  +W C  C
Sbjct: 723 GPSIDEDAVCSICMDGECQNSNVILFCDMCNLAVHQECY--GVPYIPEGQWLCRRC 884
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|19527014|ref|NP_598559.1| exonuclease 3'-5' domain
containing 2 [Mus musculus]
         (496 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

17528                                                                 135   4e-32
14179                                                                  94   2e-19
21121                                                                  63   3e-10
31848                                                                  31   1.5  
19339                                                                  29   4.0  
33985                                                                  28   6.5  
>17528
          Length = 459

 Score =  135 bits (340), Expect = 4e-32,   Method: Compositional matrix adjust.
 Identities = 60/103 (58%), Positives = 76/103 (73%)
 Frame = +1

Query: 211 RKHKRKPLGVGYSARKSPLYDNCFLQAPDGQPLCTCDRRKAQWYLDKGIGELVSKEPFVV 270
           +K  +K  G  YS R  PL+DNC L APDGQPLCTCD RKA WY+ KG+G+ VS  P VV
Sbjct: 145 KKSDKKQNGDMYSTRTRPLWDNCELLAPDGQPLCTCDTRKAAWYISKGLGDKVSDSPLVV 324

Query: 271 RLQFEPAGRPESPGDYYLMVKENLCVVCGKTDTYIRKNIIPHE 313
           +L+FEP+GRP+   +YYL  KEN+CVVCG T++Y RK I+P +
Sbjct: 325 KLRFEPSGRPKDGRNYYLQQKENMCVVCGTTESYARKFIVPQD 453
>14179
          Length = 725

 Score = 93.6 bits (231), Expect = 2e-19,   Method: Compositional matrix adjust.
 Identities = 47/111 (42%), Positives = 71/111 (63%)
 Frame = -2

Query: 1   MASPSGFCALVRLPRLIYGGRTLPRTLLDILADGAILKVGVGCSEDANKLLQDYGLIVRG 60
           +AS SGFC LVRL  +  G   +P++L  +LAD ++LK+GV  ++DA KL++DY L V G
Sbjct: 334 IASSSGFCVLVRLCSM--GADGIPQSLKSLLADKSVLKLGVAVNDDAKKLMRDYRLKVHG 161

Query: 61  CLDLRYLAMKQGNNILCNGLSLKSLAETILNFPLDKSLLLRCSNWDAENLT 111
           C+DLR++  +  +   C    L+ LA+ +LN  L K   +RC NW+  +LT
Sbjct: 160 CVDLRHILQRVRSTYKCRSWGLQGLAKGVLNVSLSKDFKVRCGNWETPHLT 8
>21121
          Length = 559

 Score = 62.8 bits (151), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 29/61 (47%), Positives = 43/61 (70%)
 Frame = +1

Query: 418 EAASLETRIYNESYIPHGLKVVQRHTEGGLRSLMQLESRWRQHFLDSMQPKHLPQQWSVD 477
           EA +++ +  +ESYI HG +VV+   + G   L+Q + RWRQHF+D+M+P HLP  WSVD
Sbjct: 4   EATNVDIKQASESYINHGQQVVRHMAQHG--GLIQFQVRWRQHFIDTMKPCHLPAFWSVD 177

Query: 478 H 478
           +
Sbjct: 178 Y 180
>31848
          Length = 563

 Score = 30.8 bits (68), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 15/47 (31%), Positives = 22/47 (46%)
 Frame = -1

Query: 407 NTDIITEEMLHEAASLETRIYNESYIPHGLKVVQRHTEGGLRSLMQL 453
            TD +  +        E R++NESY+ HG    Q     G RSL ++
Sbjct: 464 KTDPVDRQPAVAVVGKEWRLFNESYVRHGKNFCQIQKAVGTRSLKEV 324
>19339
          Length = 961

 Score = 29.3 bits (64), Expect = 4.0,   Method: Compositional matrix adjust.
 Identities = 13/32 (40%), Positives = 21/32 (65%), Gaps = 1/32 (3%)
 Frame = -2

Query: 3   SPSGFCALVRLPRLI-YGGRTLPRTLLDILAD 33
           SP+G C+   LP L+  GG+ +PRT++ + A 
Sbjct: 360 SPAGACSTAPLPPLVSAGGKFVPRTVITLTAS 265
>33985
          Length = 723

 Score = 28.5 bits (62), Expect = 6.5,   Method: Compositional matrix adjust.
 Identities = 12/24 (50%), Positives = 17/24 (70%)
 Frame = -1

Query: 329 DVLLLCTSCHAISNYYDNHLKQQL 352
           D+LLL ++ H IS Y+D+H K  L
Sbjct: 141 DLLLLFSTNHNISTYFDHHWKMTL 70
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|139948802|ref|NP_057932.2| ubiquitin
carboxyl-terminal esterase L3 [Mus musculus]
         (230 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

18699                                                                 133   6e-32
10106                                                                  80   6e-16
>18699
          Length = 601

 Score =  133 bits (334), Expect = 6e-32,   Method: Compositional matrix adjust.
 Identities = 61/123 (49%), Positives = 85/123 (69%)
 Frame = -3

Query: 13  PEVTNQFLKQLGLHPNWQFVDVYGMEPELLSMVPRPVCAVLLLFPITEKYEVFRTEEEEK 72
           P V N++L  LG+   WQFVD+YG+EPELLSMVP+PV AV+LL+P+T+K +  +   E+ 
Sbjct: 593 PTVLNKYLGNLGVSKEWQFVDIYGLEPELLSMVPKPVAAVMLLYPLTDKVDAAKIGTED- 417

Query: 73  IKSQGQDVTSSVYFMKQTISNACGTIGLIHAIANNKDKMHFESGSTLKKFLEESVSMSPE 132
                +    SVYFMKQ+ISNACGT+ L+HA+ANN+  + FE     K FLE +  +SPE
Sbjct: 416 ----AEYNAESVYFMKQSISNACGTVALVHALANNEKHIXFEDDKHFKVFLENTKGLSPE 249

Query: 133 ERA 135
           ++ 
Sbjct: 248 KKG 240

 Score = 94.4 bits (233), Expect = 3e-20,   Method: Compositional matrix adjust.
 Identities = 47/98 (47%), Positives = 61/98 (62%)
 Frame = -2

Query: 118 TLKKFLEESVSMSPEERAKFLENYDAIRVTHETSAHEGQTEAPSIDEKVDLHFIALVHVD 177
           T +    E   +   ++   LE  + +   HE +A EG T+APS D KV+ HFI+ VHVD
Sbjct: 294 TFQSVSGEHQGLESRKKGAHLEQDEKMGAVHEENALEGDTQAPSRDTKVNPHFISFVHVD 115

Query: 178 GHLYELDGRKPFPINHGKTSDETLLEDAIEVCKKFMER 215
           G LYE+DGRK  P+NHG TS + LLE+A  V KKFM R
Sbjct: 114 GTLYEMDGRKDAPVNHGPTSADNLLENAAAVAKKFMTR 1
>10106
          Length = 1115

 Score = 80.5 bits (197), Expect = 6e-16,   Method: Compositional matrix adjust.
 Identities = 64/228 (28%), Positives = 102/228 (44%), Gaps = 6/228 (2%)
 Frame = +2

Query: 6   WLPLEANPEVTNQFLKQLGLHPNWQFVDVYGMEPELLSMVPRPVCAVLLLFPITEKYEVF 65
           W  +E++P V  + +K  G     Q  +++ ++ E   ++ +PV  ++ LF         
Sbjct: 5   WCLIESDPGVFTELIKGFGC-TGVQVEEIWSLDKESFELL-KPVHGLIFLFKWVP----- 163

Query: 66  RTEEEEKIKSQGQDVT-SSVYFMKQTISNACGTIGLIHAIANNKDKMHFESGSTLKKFLE 124
              ++E   S  QD     ++F KQ I+NAC T  ++ +I  N        G TL  F E
Sbjct: 164 ---DKEPDGSVVQDSRLEKIFFAKQVINNACATQAIL-SILLNCSHADISLGDTLSSFKE 331

Query: 125 ESVSMSPEERAKFLENYDAIRVTHETSAHEGQTEAPSIDEKVD---LHFIALVHVDGHLY 181
            +    P  R   L N D IR  H + + +   E      K D    HF+  +  DG LY
Sbjct: 332 FAQQFDPALRGLSLSNSDLIREVHNSFSRQQMFEFDEKMAKKDDDVFHFVGYIPFDGRLY 511

Query: 182 ELDGRKPFPINHGKTSDETLLEDAIE--VCKKFMERDPDELRFNAIAL 227
           ELDG K  P++ G    ET   D +   + K+  +   DE+ FN +A+
Sbjct: 512 ELDGLKDGPVDLGAIPTETEWTDVVRPVIEKRMQKYSADEIHFNLMAV 655
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6678049|ref|NP_033248.1| synaptosomal-associated
protein 23 [Mus musculus]
         (210 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

08192                                                                 133   6e-32
21259                                                                 100   6e-22
07328                                                                  40   8e-04
07259                                                                  37   0.004
01907                                                                  29   1.1  
>08192
          Length = 768

 Score =  133 bits (334), Expect = 6e-32,   Method: Compositional matrix adjust.
 Identities = 64/136 (47%), Positives = 89/136 (65%)
 Frame = +2

Query: 73  LTELNKCCGLCICPCNRTKNFESGKNYKATWGDGGDNSPSNVVSKQPSRITNGQPQQTTG 132
           L  L KCCGLC+ P  R+KNFE G +Y  TW    D      V+    R+  G      G
Sbjct: 95  LEGLEKCCGLCVLPWKRSKNFEKGSDYNKTWKSNDDGK----VNTNGPRVVVGDA--NGG 256

Query: 133 AASGGYIKRITNDAREDEMEENLTQVGSILGNLKNMALDMGNEIDAQNQQIQKITEKADT 192
             SGGY+ RI NDAREDEME+N+ +V  ++GNL+NMA+DMGNEI++QN+QI ++ +K  +
Sbjct: 257 MVSGGYVTRIMNDAREDEMEQNIGEVSGMIGNLRNMAVDMGNEIESQNRQIDRVNQKGVS 436

Query: 193 NKNRIDIANTRAKKLI 208
             +R+D+AN RA K++
Sbjct: 437 LNDRVDVANQRAHKIL 484

 Score = 62.4 bits (150), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 29/52 (55%), Positives = 35/52 (67%)
 Frame = +3

Query: 42 ITMLDEQGEQLNRIEEGMDQINKDMREAEKTLTELNKCCGLCICPCNRTKNF 93
          + MLDEQGEQL+RIEEGMDQIN+DM++AEKT        G   CP N  +  
Sbjct: 3  LVMLDEQGEQLDRIEEGMDQINQDMKDAEKTSRVWRSVVGSVSCPGNGPRTL 158
>21259
          Length = 425

 Score =  100 bits (248), Expect = 6e-22,   Method: Compositional matrix adjust.
 Identities = 49/66 (74%), Positives = 60/66 (90%)
 Frame = -1

Query: 7   EEVQLRAHQVTDESLESTRRILGLAIESQDAGIKTITMLDEQGEQLNRIEEGMDQINKDM 66
           +++Q++A+ VTDESLESTRR+L L  ESQD GIKTI MLDEQGEQL+RIEEGMDQIN+DM
Sbjct: 224 QDLQMQANVVTDESLESTRRMLALCEESQDVGIKTIVMLDEQGEQLDRIEEGMDQINQDM 45

Query: 67  REAEKT 72
           ++AEKT
Sbjct: 44  KDAEKT 27
>07328
          Length = 1336

 Score = 39.7 bits (91), Expect = 8e-04,   Method: Compositional matrix adjust.
 Identities = 22/61 (36%), Positives = 34/61 (55%)
 Frame = -1

Query: 148 EDEMEENLTQVGSILGNLKNMALDMGNEIDAQNQQIQKITEKADTNKNRIDIANTRAKKL 207
           E+  +E L  + S LG LK+MA  +G E+  QNQ +  +    D  ++R+  A  R KKL
Sbjct: 229 EEXSQEELAALCSKLGALKSMAGAVGEELTNQNQALDNMIHSVDHAESRVRDATRRTKKL 50

Query: 208 I 208
           +
Sbjct: 49  M 47
>07259
          Length = 993

 Score = 37.4 bits (85), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 16/32 (50%), Positives = 23/32 (71%)
 Frame = +2

Query: 166 KNMALDMGNEIDAQNQQIQKITEKADTNKNRI 197
           K MA+D+GNE+D Q++ I  IT+  D+  NRI
Sbjct: 74  KQMAIDIGNEVDLQDELIDDITDHVDSTGNRI 169
>01907
          Length = 1360

 Score = 29.3 bits (64), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 20/69 (28%), Positives = 29/69 (42%), Gaps = 9/69 (13%)
 Frame = -3

Query: 58  GMDQINKDMREA-----EKTLTELNKCCGLCICPCNRTKNFESGKNYKATWGDGGDNS-- 110
           G+D +NK  +       EK +   N    LC+C C RT   +   +Y A  G    ++  
Sbjct: 776 GIDHVNKTAKRTRYSYQEKAIKIHN*PACLCVCVCVRTVGVDLVMDYTALPGSSASSTVA 597

Query: 111 --PSNVVSK 117
             P  VV K
Sbjct: 596 VFPHGVVWK 570
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|56699438|ref|NP_083939.1| eukaryotic translation
elongation factor 1 delta isoform a [Mus musculus]
         (660 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

00432                                                                 135   8e-32
03891                                                                  50   3e-06
>00432
          Length = 1557

 Score =  135 bits (339), Expect = 8e-32,   Method: Compositional matrix adjust.
 Identities = 64/97 (65%), Positives = 80/97 (82%)
 Frame = -1

Query: 564  KKAKKPTLVAKSSILLDVKPWDDETDMAQLETCVRSIQLDGLVWGASKLVPVGYGIRKLQ 623
            KK+ KP L+AKSS++LD KPWDDETDM ++E  VRSIQ DGL WGA+KL  + YGI+KL 
Sbjct: 1221 KKSAKPALIAKSSVVLDCKPWDDETDMKEMERLVRSIQKDGLNWGAAKLQELAYGIKKLV 1042

Query: 624  IQCVVEDDKVGTDLLEEEITKFEEHVQSVDIAAFNKI 660
            I CVVED+K+  + L+EEI +FE++VQSVDIAAFNKI
Sbjct: 1041 IICVVEDEKISVEDLKEEIEEFEDYVQSVDIAAFNKI 931

 Score = 39.7 bits (91), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 18/37 (48%), Positives = 25/37 (67%)
 Frame = -2

Query: 462  RITSLEVENQNLRGVVQDLQQAISKLEARLSSLEKSS 498
            R+  LE EN++LR    DL+Q I KLE R+++LEK  
Sbjct: 1478 RLDDLEKENKDLRKTTNDLRQLIKKLEGRVTALEKGG 1368
>03891
          Length = 1119

 Score = 50.1 bits (118), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 26/57 (45%), Positives = 31/57 (54%)
 Frame = +3

Query: 533 DKDIDLFGSXXXXXXXXXXXXXXXXXXQYAEKKAKKPTLVAKSSILLDVKPWDDETD 589
           D D DLFG                   +Y  KK+ KP L+AKSS++LD KPWDDETD
Sbjct: 3   DDDFDLFGDEDEEETAAREKEKKELVEKYKAKKSAKPALIAKSSVVLDCKPWDDETD 173
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|23956138|ref|NP_075737.1| Shwachman-Bodian-Diamond
syndrome homolog [Mus musculus]
         (250 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

28473                                                                 132   1e-31
21111                                                                  73   1e-13
34206                                                                  65   2e-11
>28473
          Length = 407

 Score =  132 bits (332), Expect = 1e-31,   Method: Compositional matrix adjust.
 Identities = 61/107 (57%), Positives = 81/107 (75%)
 Frame = -2

Query: 69  EDLISAFGTDDQTEICKQILTKGEVQVSDKERHTQLEQMFRDIATIVADKCVNPETKRPY 128
           ++L  AFG  D+TEICK+IL+KGE+QVS+KERH+ L+     I   VA  CVNPET+RPY
Sbjct: 406 DELQKAFGAKDETEICKEILSKGELQVSEKERHSVLDSQLNSIVNSVAALCVNPETRRPY 227

Query: 129 TVILIERAMKDIHYSVKPNKSTKQQALEVIKQLKEKMKIERAHMRLR 175
           +  +IE+++KD H+SVK NK+TKQ  LE IK L+E M IER+ M+LR
Sbjct: 226 SSTIIEKSLKDAHFSVKMNKNTKQNTLEAIKVLREHMPIERSRMKLR 86
>21111
          Length = 375

 Score = 73.2 bits (178), Expect = 1e-13,   Method: Compositional matrix adjust.
 Identities = 38/86 (44%), Positives = 54/86 (62%)
 Frame = +2

Query: 165 MKIERAHMRLRFILPXXXXXXXXXXXXXXXXXXXSEDYSQQLEIVCLIDPGCFREIDELI 224
           +KI+RA+MRLR + P                    ED+ + LE+V L+DPGC+RE+DEL+
Sbjct: 101 LKIQRAYMRLRVVAPAREGKKVREKVKKLATTVEEEDFEEHLEMVVLVDPGCYRELDELV 280

Query: 225 KKETKGRGSLEVLSLKDVEEGDEKFE 250
           + ET+G+G +EVLSLK V E +E  E
Sbjct: 281 QTETRGKGKIEVLSLKHVNEAEEALE 358
>34206
          Length = 292

 Score = 65.1 bits (157), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 27/49 (55%), Positives = 39/49 (79%)
 Frame = +2

Query: 202 YSQQLEIVCLIDPGCFREIDELIKKETKGRGSLEVLSLKDVEEGDEKFE 250
           + + LE+V L+DPGC+RE+DEL++ ET+G+G +EVLSLK V E +E  E
Sbjct: 128 FEEHLEMVVLVDPGCYRELDELVQTETRGKGKIEVLSLKHVNEAEEALE 274
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6680297|ref|NP_032324.1| DnaJ (Hsp40) homolog,
subfamily A, member 1 [Mus musculus]
         (397 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

12040                                                                 134   1e-31
14550                                                                 111   6e-25
10680                                                                  99   2e-21
20488                                                                  99   4e-21
13998                                                                  47   2e-05
02324                                                                  46   3e-05
26984                                                                  44   2e-04
02088                                                                  35   0.039
22505                                                                  30   0.067
38321                                                                  32   0.33 
36566                                                                  28   5.7  
>12040
          Length = 1151

 Score =  134 bits (336), Expect = 1e-31,   Method: Compositional matrix adjust.
 Identities = 65/148 (43%), Positives = 100/148 (67%)
 Frame = -2

Query: 238  DIIIVLDQKDHAVFTRRGEDLFMCMDIQLVEALCGFQKPISTLDNRTIVITSHPGQIVKH 297
            DIII+LD+K+H+ F   G DL M M +QLVEALCGFQ+ + T+D+R +++ + PG++++H
Sbjct: 1150 DIIILLDEKEHSTFVHAGTDLMMKMPLQLVEALCGFQRIVKTMDDRDLLVATQPGEVIRH 971

Query: 298  GDIKCVLNEGMPIYRRPYEKGRLIIEFKVNFPENGFLSPDKLSLLEKLLPERKEVEETDE 357
               KC+  EGMPI++ P EKG LII+F+V FP+   ++P  +  L++ LP   E++   E
Sbjct: 970  EMTKCIAEEGMPIFKNPMEKGTLIIQFEVIFPD--VINPSVIPTLKQCLPPAPEIDIPIE 797

Query: 358  MDQVELVDFDPNQERRRHYNGEAYEDDE 385
             +   L DFDP Q RR+     AY++D+
Sbjct: 796  AEHTVLEDFDPKQ-RRQPNQRMAYDEDD 716
>14550
          Length = 1395

 Score =  111 bits (277), Expect = 6e-25,   Method: Compositional matrix adjust.
 Identities = 81/240 (33%), Positives = 115/240 (47%), Gaps = 4/240 (1%)
 Frame = -2

Query: 106 NVVHQLSVTLEDLYNGATRKLALQKNVICDKCEGRGGKKGAVECCPNCRGTGMQIRIHQI 165
           +VV  L VTLE+LY+G   ++   K V           KG  +C  NCR   M+    Q+
Sbjct: 809 DVVMDLDVTLEELYSGDFVEVLRYKPV-------SKPAKGKRKC--NCR---METVTQQL 666

Query: 166 GPGMVQQIQSVCMECQGHGERISPKDRCKSCNGRKIVREKKILEVHIDKGMKDGQKITFH 225
           GPG  Q               +S +  C  C   K V E+K+LEV I+ GM+DGQ+  F 
Sbjct: 665 GPGRFQ---------------MSQQQVCDECPNIKFVPEEKVLEVEIEPGMRDGQEYPFV 531

Query: 226 GEGDQEPGLEPGDIIIVLDQKDHAVFTRRGEDLFMCMDIQLVEALCGFQKPISTLDNRTI 285
            EG+     EPGD+  ++ Q  HA F R+G+DL+  + + L +AL GF+  I  LD   +
Sbjct: 530 AEGEPHMDGEPGDLRFIIRQVKHARFERKGDDLYTNVTVSLQDALIGFEMDIVHLDGHKV 351

Query: 286 VI----TSHPGQIVKHGDIKCVLNEGMPIYRRPYEKGRLIIEFKVNFPENGFLSPDKLSL 341
            +     + PG  ++        NEGMP Y     KG L I F ++FP+      DK  L
Sbjct: 350 HVIRDKITWPGARMRKS------NEGMPNYENNNVKGSLFITFDIDFPKGTLSEEDKEGL 189

 Score = 45.1 bits (105), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 22/62 (35%), Positives = 35/62 (56%), Gaps = 3/62 (4%)
 Frame = -1

Query: 7    YYDVLGVKPNATQEEXXXXXXXXXXXXHPDKN---PNEGEKFKQISQAYEVLADSKKREL 63
            +Y +LGV  +A  ++            HPDKN   P   ++F+ +  AYEVL+D +KR++
Sbjct: 1131 FYKILGVSKSADTKQIKRAYRKIAKELHPDKNRDDPEAEQRFQDLGAAYEVLSDEEKRKV 952

Query: 64   YD 65
            YD
Sbjct: 951  YD 946

 Score = 32.3 bits (72), Expect = 0.33,   Method: Compositional matrix adjust.
 Identities = 16/37 (43%), Positives = 19/37 (51%)
 Frame = -1

Query: 305  NEGMPIYRRPYEKGRLIIEFKVNFPENGFLSPDKLSL 341
            NEGMP Y     KG L I F ++FP+      DK  L
Sbjct: 1383 NEGMPNYENNNVKGSLFITFDIDFPKGTLSEEDKEGL 1273
>10680
          Length = 1093

 Score = 99.4 bits (246), Expect = 2e-21,   Method: Compositional matrix adjust.
 Identities = 62/155 (40%), Positives = 83/155 (53%)
 Frame = -3

Query: 192 RCKSCNGRKIVREKKILEVHIDKGMKDGQKITFHGEGDQEPGLEPGDIIIVLDQKDHAVF 251
           R  + +G       KIL + + KG K G KITF  EGDQ P   P DI+ ++  K H  F
Sbjct: 770 RVMNEDGHTSSIRDKILTITVKKGWKPGTKITFPKEGDQGPNNVPADIVFIVKDKPHPRF 591

Query: 252 TRRGEDLFMCMDIQLVEALCGFQKPISTLDNRTIVITSHPGQIVKHGDIKCVLNEGMPIY 311
            R G +L    ++ L  AL G    I TLD+RT+ I  +   IVK G  K V  EGMP+ 
Sbjct: 590 RREGLNLIHTANVLLGRALTGTTVDIHTLDDRTLHIPIN--DIVKPGYKKIVPGEGMPMS 417

Query: 312 RRPYEKGRLIIEFKVNFPENGFLSPDKLSLLEKLL 346
             P +KG LIIEF + FP +  L+P++  L+   L
Sbjct: 416 SDPTQKGDLIIEFNIEFPTS--LTPERKDLIRTAL 318
>20488
          Length = 3281

 Score = 98.6 bits (244), Expect = 4e-21,   Method: Compositional matrix adjust.
 Identities = 60/141 (42%), Positives = 78/141 (55%)
 Frame = -2

Query: 206  KILEVHIDKGMKDGQKITFHGEGDQEPGLEPGDIIIVLDQKDHAVFTRRGEDLFMCMDIQ 265
            KIL + + KG K G KITF  EGDQ P   P DI+ ++  K H  F R G +L    ++ 
Sbjct: 1585 KILTITVKKGWKPGTKITFPKEGDQGPNNVPADIVFIVKDKPHPRFRREGLNLIHTANVL 1406

Query: 266  LVEALCGFQKPISTLDNRTIVITSHPGQIVKHGDIKCVLNEGMPIYRRPYEKGRLIIEFK 325
            L  AL G    I TLD+RT+ I  +   IVK G  K V  EGMP+   P ZKG LIIEF 
Sbjct: 1405 LGRALTGTTVDIHTLDDRTLHIPIN--DIVKPGYKKIVPGEGMPMSSDPTZKGDLIIEFN 1232

Query: 326  VNFPENGFLSPDKLSLLEKLL 346
            + FP +  L+P++  L+   L
Sbjct: 1231 IEFPTS--LTPERKDLIRTAL 1175
>13998
          Length = 1075

 Score = 46.6 bits (109), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 23/71 (32%), Positives = 35/71 (49%), Gaps = 8/71 (11%)
 Frame = +1

Query: 3   KETTYYDVLGVKPNATQEEXXXXXXXXXXXXHPDKNPNEGE--------KFKQISQAYEV 54
           K   YY +LG+  NAT++E            HPD++ N           KFK++ +AY +
Sbjct: 196 KRKDYYKILGISRNATEDEIKKAYRKKALVHHPDRHANSSADVRKDEELKFKEVGEAYAI 375

Query: 55  LADSKKRELYD 65
           L+D  K+  YD
Sbjct: 376 LSDGAKKTRYD 408
>02324
          Length = 2058

 Score = 45.8 bits (107), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 23/63 (36%), Positives = 36/63 (57%), Gaps = 4/63 (6%)
 Frame = +2

Query: 7   YYDVLGVKPNATQEEXXXXXXXXXXXXHPDKNPNEGE----KFKQISQAYEVLADSKKRE 62
           +Y+VLGV+ +A  ++            HPDKNP+  E    +F+ + QAYE+L D ++R 
Sbjct: 107 HYEVLGVERSADNDDLKKAYRKLALKFHPDKNPDSVEEATAQFRLVQQAYEILTDPQERS 286

Query: 63  LYD 65
            YD
Sbjct: 287 WYD 295
>26984
          Length = 1107

 Score = 43.5 bits (101), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 21/60 (35%), Positives = 32/60 (53%), Gaps = 2/60 (3%)
 Frame = -2

Query: 8   YDVLGVKPNATQEEXXXXXXXXXXXXHPDKN--PNEGEKFKQISQAYEVLADSKKRELYD 65
           Y +LG++ +A+ E+            HPDKN  P   E FK +  A+E++ D  KR+ YD
Sbjct: 509 YSILGLRADASDEDIKRYYRRQAVLVHPDKNQEPGAEEAFKILGHAFEMIGDPTKRKEYD 330
>02088
          Length = 1062

 Score = 35.4 bits (80), Expect = 0.039,   Method: Compositional matrix adjust.
 Identities = 22/70 (31%), Positives = 35/70 (50%), Gaps = 5/70 (7%)
 Frame = +3

Query: 1   MVKETTYYDVLGVKPNATQEEXXXXXXXXXXXXHPDK-NPNEGE----KFKQISQAYEVL 55
           + + T  Y+V+G++  AT +E            HPD+ +  E E    KF+ + + Y VL
Sbjct: 93  LFETTDLYEVIGIRREATPQEVKKGYHKVSLAVHPDQVSAAEKETATRKFQTLGKVYTVL 272

Query: 56  ADSKKRELYD 65
           +D  KR  YD
Sbjct: 273 SDKDKRAXYD 302
>22505
          Length = 784

 Score = 29.6 bits (65), Expect(2) = 0.067,   Method: Compositional matrix adjust.
 Identities = 14/32 (43%), Positives = 19/32 (59%)
 Frame = -3

Query: 34  HPDKNPNEGEKFKQISQAYEVLADSKKRELYD 65
           +PD NP   E F ++S+A EVL D   +  YD
Sbjct: 557 NPD-NPKAAELFHELSKALEVLTDPSAKAAYD 465

 Score = 23.9 bits (50), Expect(2) = 0.067,   Method: Compositional matrix adjust.
 Identities = 10/31 (32%), Positives = 14/31 (45%)
 Frame = -1

Query: 8   YDVLGVKPNATQEEXXXXXXXXXXXXHPDKN 38
           Y +LGV P A +++            HPDK 
Sbjct: 646 YGILGVGPEANEKQIVKAYRKKALKCHPDKT 554
>38321
          Length = 1059

 Score = 32.3 bits (72), Expect = 0.33,   Method: Compositional matrix adjust.
 Identities = 16/37 (43%), Positives = 19/37 (51%)
 Frame = -1

Query: 305  NEGMPIYRRPYEKGRLIIEFKVNFPENGFLSPDKLSL 341
            NEGMP Y     KG L I F ++FP+      DK  L
Sbjct: 1047 NEGMPNYENNNVKGSLFITFDIDFPKGTLSEEDKEGL 937
>36566
          Length = 589

 Score = 28.1 bits (61), Expect = 5.7,   Method: Compositional matrix adjust.
 Identities = 18/63 (28%), Positives = 27/63 (42%)
 Frame = -1

Query: 124 RKLALQKNVICDKCEGRGGKKGAVECCPNCRGTGMQIRIHQIGPGMVQQIQSVCMECQGH 183
           R L +++ V+      RGG      C      TG   ++   GP M+  I  +CM  +G 
Sbjct: 553 RTLMIRRRVMMGSPTWRGG------CLITSWSTGSTPKLCAGGPSMMMLIHRICMAFRGL 392

Query: 184 GER 186
           G R
Sbjct: 391 GRR 383
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|157277948|ref|NP_033067.2| radixin isoform a [Mus
musculus]
         (583 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

00990                                                                 133   2e-31
17332                                                                  82   8e-16
18811                                                                  56   5e-08
13951                                                                  45   1e-04
08616                                                                  33   0.29 
>00990
          Length = 3161

 Score =  133 bits (334), Expect = 2e-31,   Method: Compositional matrix adjust.
 Identities = 92/301 (30%), Positives = 154/301 (51%), Gaps = 9/301 (2%)
 Frame = +3

Query: 3   KPINVRVTTMDAE-LEFAIQPNTTGKQLFDQVVKTVGLREVWFFGLQYVD---SKGYSTW 58
           K  N  V  +D E + F +  N  G++LFD+V + + L E  +FGLQ+VD   S     W
Sbjct: 252 KGFNYEVVLLDGEHVNFELDRNAEGRELFDKVCQHLDLIEKDYFGLQFVDERISNHLKCW 431

Query: 59  LKLNKKVTQQDVKKENPLQFKFRAKFFPEDVSEELIQEITQRLFFLQVKEAILNDEIYCP 118
           L  +K++++Q  KK  P  F F  KF+P D ++ L + +T+ L  LQ +  IL+ ++   
Sbjct: 432 LSPDKRISKQ--KKGGPWLFDFALKFYPPDPTQ-LRESLTRWLVVLQTRRDILSGKLPAT 602

Query: 119 PETAVLLASYAVQAKYGDYNKEIHKPG-YLANDRLLPQRVLEQHKLTKEQWEERIQNWHE 177
             T  +L SY VQA  GDY+   H+   Y+ +    P + ++          E+I   H 
Sbjct: 603 YLTQAMLGSYCVQADVGDYDPNEHRGVEYIRDTPFAPNQTIDLL--------EKIVELHR 758

Query: 178 EHRGMLREDSMMEYLKIAQDLEMYGVNYFEIKNKKGTELWLGVDALGLNIYEHDDKLTPK 237
           +H+G   +++   +L+ A+ L MYGV+    ++    ++ LGV A GL +Y    +++  
Sbjct: 759 QHKGQTPDEAETNFLENAKKLAMYGVDLHAAQDVNNVDIMLGVCASGLQVYREKLRIS-- 932

Query: 238 IGFPWSEIRNISFNDKKFVIK--PIDKKAPD--FVFYAPRLRINKRILALCMGNHELYMR 293
             F W +I  IS+  ++F IK  P D  A +  F F     R+ KR+  +C+ +H  +  
Sbjct: 933 -RFVWPKILKISYKRRQFYIKVRPSDNSAMENSFCFKLATHRLAKRLWKICVEHHAFFRL 1109

Query: 294 R 294
           R
Sbjct: 1110R 1112
>17332
          Length = 473

 Score = 81.6 bits (200), Expect = 8e-16,   Method: Composition-based stats.
 Identities = 51/164 (31%), Positives = 88/164 (53%)
 Frame = +2

Query: 13  DAELEFAIQPNTTGKQLFDQVVKTVGLREVWFFGLQYVDSKGYSTWLKLNKKVTQQDVKK 72
           D++ +  ++ N  G  L ++V + + L E  +FGL+++D+ G + WL  NK ++ Q    
Sbjct: 5   DSDHQLQVKGNWKGILLQEKVCELLNLHEKDYFGLRFIDASGQTHWLDGNKSLSSQLKGC 184

Query: 73  ENPLQFKFRAKFFPEDVSEELIQEITQRLFFLQVKEAILNDEIYCPPETAVLLASYAVQA 132
           + P +  F  KF+  D  + L +EIT+ LFFLQVK+ IL   +    + A  L +YAVQ+
Sbjct: 185 QTPHKLYFGVKFYAADPCK-LREEITRYLFFLQVKQDILQGRLPVTFDEASELCAYAVQS 361

Query: 133 KYGDYNKEIHKPGYLANDRLLPQRVLEQHKLTKEQWEERIQNWH 176
           + GD++   H  GY++    +P +         E+ E R+   H
Sbjct: 362 ELGDFDPRQHTDGYVSEFCFIPNQT--------EELERRVAGLH 469
>18811
          Length = 478

 Score = 55.8 bits (133), Expect = 5e-08,   Method: Compositional matrix adjust.
 Identities = 39/116 (33%), Positives = 61/116 (52%), Gaps = 5/116 (4%)
 Frame = -2

Query: 170 ERIQNWHEEHRGMLREDSMMEYLKIAQDLEMYGVNYFEIKNKKGTELWLGVDALGLNIYE 229
           E+I   H +H+G   +++ + YL+ A+ L MYGV+    ++    ++ LGV + GL +Y 
Sbjct: 342 EKIVELHRQHKGQTPDEAEVNYLENAKKLSMYGVDLHAAQDVNNVDIMLGVCSSGLQVYR 163

Query: 230 HDDKLTPKIG-FPWSEIRNISFNDKKFVIK--PIDKKA--PDFVFYAPRLRINKRI 280
             DKL  +I  F W +I  IS+  K F +K  P D K       F  P  R+ KR+
Sbjct: 162 --DKL--RISRFVWPKIIKISYKRKHFYVKVRPADNKGLETSVSFRLPTHRLAKRL 7
>13951
          Length = 720

 Score = 44.7 bits (104), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 24/69 (34%), Positives = 39/69 (56%), Gaps = 4/69 (5%)
 Frame = -2

Query: 3   KPINVRVTTMDAE-LEFAIQPNTTGKQLFDQVVKTVGLREVWFFGLQYVD---SKGYSTW 58
           K  N  V  +D E + F +  N  G++LFD+V + + L E  +FGLQ+VD   S     W
Sbjct: 398 KGFNYEVVLLDGEHVNFELDRNAEGRELFDKVCQHLDLIEKDYFGLQFVDERISNHLKCW 219

Query: 59  LKLNKKVTQ 67
           L  +K++++
Sbjct: 218 LSPDKRISK 192
>08616
          Length = 2833

 Score = 33.1 bits (74), Expect = 0.29,   Method: Compositional matrix adjust.
 Identities = 22/53 (41%), Positives = 28/53 (52%), Gaps = 2/53 (3%)
 Frame = +2

Query: 170  ERIQNWHEEHRGMLREDSMMEYLKIAQDLEMYGVNYFEIK--NKKGTELWLGV 220
            +RI   H   R M   ++ M Y+K  Q L  +G+ YF IK  N K  EL LGV
Sbjct: 1046 QRIMEAHANVREMSLMEAKMAYIKAWQSLPEFGITYFRIKMANSKKEEL-LGV 1201
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|22165347|ref|NP_035638.1| eukaryotic translation
initiation factor 1 [Mus musculus]
         (113 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

02296                                                                 129   2e-31
01429                                                                  75   7e-15
20802                                                                  25   6.4  
08591                                                                  25   7.4  
14732                                                                  25   9.6  
>02296
          Length = 630

 Score =  129 bits (325), Expect = 2e-31,   Method: Compositional matrix adjust.
 Identities = 68/116 (58%), Positives = 77/116 (66%), Gaps = 3/116 (2%)
 Frame = -1

Query: 1   MSAIQNLHSFDPFADASKGDDLLPAG---TEDYIHIRIQQRNGRKTLTTVQGIADDYDXX 57
           M+   NL  FDPFAD    DD   AG   TE  IHIRIQQRNGRKTLTTVQGI   +D  
Sbjct: 441 MTEFGNLKGFDPFADT---DDSSAAGAGQTEGLIHIRIQQRNGRKTLTTVQGINPKFDLR 271

Query: 58  XXXXXXXXXXXCNGTVIEHPEYGEVIQLQGDQRKNICQFLIEIGLAKDDQLKVHGF 113
                      CNGTV+EHPEYGEVIQLQGD+R+ +  FLIE+G+A  D +KVHGF
Sbjct: 270 KMVKVCKKDFNCNGTVVEHPEYGEVIQLQGDKREAVRTFLIEVGIASSDLVKVHGF 103
>01429
          Length = 568

 Score = 75.1 bits (183), Expect = 7e-15,   Method: Compositional matrix adjust.
 Identities = 32/45 (71%), Positives = 39/45 (86%)
 Frame = -2

Query: 69  CNGTVIEHPEYGEVIQLQGDQRKNICQFLIEIGLAKDDQLKVHGF 113
           CNGTV+EHPEYGEVIQLQGD+R+ +  FLIE+G+A  D +KVHGF
Sbjct: 519 CNGTVVEHPEYGEVIQLQGDKREAVRTFLIEVGIASSDLVKVHGF 385
>20802
          Length = 526

 Score = 25.4 bits (54), Expect = 6.4,   Method: Compositional matrix adjust.
 Identities = 11/28 (39%), Positives = 16/28 (57%)
 Frame = -3

Query: 2   SAIQNLHSFDPFADASKGDDLLPAGTED 29
           SAI +L  F PF   S+ +  +PA + D
Sbjct: 392 SAIHSLPDFPPFLHCSRPNSSIPASSTD 309
>08591
          Length = 1037

 Score = 25.0 bits (53), Expect = 7.4,   Method: Compositional matrix adjust.
 Identities = 12/20 (60%), Positives = 14/20 (70%), Gaps = 2/20 (10%)
 Frame = -2

Query: 15  DASKGDDLLPAG--TEDYIH 32
            AS+GD LLPAG  T D+ H
Sbjct: 184 SASEGDGLLPAGIRTRDFAH 125
>14732
          Length = 1080

 Score = 24.6 bits (52), Expect = 9.6,   Method: Compositional matrix adjust.
 Identities = 11/17 (64%), Positives = 13/17 (76%)
 Frame = -3

Query: 30   YIHIRIQQRNGRKTLTT 46
            YI+I  QQ+ GRKT TT
Sbjct: 1030 YIYIYKQQKEGRKTTTT 980
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|85861224|ref|NP_038568.2| glutamate receptor,
ionotropic, AMPA 2 isoform 2 [Mus musculus]
         (883 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

34285                                                                 133   2e-31
30315                                                                 117   2e-26
14800                                                                  56   5e-08
28144                                                                  30   2.9  
>34285
          Length = 707

 Score =  133 bits (335), Expect = 2e-31,   Method: Compositional matrix adjust.
 Identities = 62/192 (32%), Positives = 115/192 (59%), Gaps = 3/192 (1%)
 Frame = +1

Query: 596 NSLWFSLGAFMRQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAA-FLTVERMVS-- 652
           NS  +   +F  QG   +PRS+SGR++   WW F L++I +YTA+L A FL  +  ++  
Sbjct: 100 NSFLYVFSSFTFQGYTAAPRSISGRVLAAFWWIFVLLVIVAYTASLCAIFLHFKPSITSL 279

Query: 653 PIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVA 712
           P ++ ++LS+Q+ +AYG    G T+ + + SK  +  ++W  + +   +V V+   EG+ 
Sbjct: 280 PFDTFDELSQQSHVAYGIAKGGMTERYLKTSKQPLQRRLWANIHANADAVMVQNIDEGLL 459

Query: 713 RVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLRNAVNLAVL 772
           RV++ +G +A ++E  + EY+ ++ PCD M +G  L    +G A  +GS + + ++ A+L
Sbjct: 460 RVQQGQGSFALIMEGPLAEYLSEQPPCDXMTLGEELSQHNWGFACQQGSGICSNLSAAIL 639

Query: 773 KLNEQGLLDKLK 784
           ++ E+ L+  LK
Sbjct: 640 QMREEELVFDLK 675
>30315
          Length = 336

 Score =  117 bits (293), Expect = 2e-26,   Method: Compositional matrix adjust.
 Identities = 54/108 (50%), Positives = 71/108 (65%)
 Frame = +2

Query: 736 RKPCDTMKVGGNLDSKGYGIATPKGSSLRNAVNLAVLKLNEQGLLDKLKNKWWYDKGECG 795
           RKPCDT++VGG+L+ +G+GIATP+GS L+  ++ A LK+ E G L +L+ KWWY+KGECG
Sbjct: 2   RKPCDTVRVGGDLNLEGFGIATPQGSELKEMISYATLKMKEDGTLHRLETKWWYEKGECG 181

Query: 796 SGGGDSKEKTSALSLSNVAGVFYIXXXXXXXXXXXXXIEFCYKSRAEA 843
           S  G  + K  +LSLSNVAGVFYI             +E C   R  A
Sbjct: 182 SDAGHRESKKRSLSLSNVAGVFYILISGLVIAILLGLLEVCLHRRHAA 325
>14800
          Length = 446

 Score = 56.2 bits (134), Expect = 5e-08,   Method: Compositional matrix adjust.
 Identities = 38/147 (25%), Positives = 71/147 (48%), Gaps = 1/147 (0%)
 Frame = +3

Query: 622 VGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLSKQTEIAYGTLDSGSTKEFFR 681
           V G+WW FT++  +SYTA+LAAFLT      PI S  DL++Q+ I     +  +    F+
Sbjct: 3   VLGLWWVFTILTTASYTASLAAFLTFSLADVPINSLYDLAQQSHIMPLVKNGTNLYTLFK 182

Query: 682 RSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDT 741
           +     + +++  M+    +  V+   +G+  V    G YA + +    + + Q+  C+ 
Sbjct: 183 KQGTPTYQRIYEMMQD---TPLVKANEDGMDLVL--SGPYALMSDREQLDLL-QKVDCEN 344

Query: 742 MKVG-GNLDSKGYGIATPKGSSLRNAV 767
           +  G    ++ G G +  + +    AV
Sbjct: 345 LVQGEETFNNNGLGFSCRRATRFGAAV 425
>28144
          Length = 1057

 Score = 30.4 bits (67), Expect = 2.9,   Method: Compositional matrix adjust.
 Identities = 16/54 (29%), Positives = 27/54 (50%)
 Frame = +2

Query: 415 TVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGD 468
           T+V   + +SP+++ KK   +L      EG CV +   + K CG  + L +  D
Sbjct: 332 TIVXNRVFKSPFLLYKKRGHLL*-----EGRCVCVCVSVYKMCGQDFLLCLWAD 478
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|226246593|ref|NP_062759.2| ARP10 actin-related
protein 10 [Mus musculus]
         (417 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

04742                                                                 132   3e-31
39562                                                                 105   4e-23
00608                                                                  60   1e-09
36954                                                                  59   5e-09
12322                                                                  55   4e-08
02757                                                                  54   1e-07
13361                                                                  44   1e-04
01436                                                                  42   4e-04
11487                                                                  41   7e-04
19721                                                                  36   0.037
27777                                                                  32   0.54 
00154                                                                  29   3.3  
>04742
          Length = 2111

 Score =  132 bits (331), Expect = 3e-31,   Method: Compositional matrix adjust.
 Identities = 103/394 (26%), Positives = 180/394 (45%), Gaps = 26/394 (6%)
 Frame = +2

Query: 15  AVVIDLGEAFTKCGFAGETGPRCIIPSVIKR--------------------AGMSKPIKV 54
           A+VID G    K GFAG+  PR + PS++ R                    A   + I  
Sbjct: 113 ALVIDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILT 292

Query: 55  VQYNINTEELYSY--LKEFIHILYFRHLLVNPRDRRVVVIESVLCPSHFRETLTRVLFKY 112
           ++Y I    + ++  +++  H  ++  L V P +  V++ E+ L P   RE +T+++F+ 
Sbjct: 293 LKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFET 472

Query: 113 FEVPSVLLAPSHLMALLTLGINSAMVLDCGYRESLVLPIYEGIPILNCWGALPLGGKALH 172
           F  P++ +A   +++L   G  + +VLD G      +PIYEG  + +    L L G+ L 
Sbjct: 473 FNSPAMYVAIQAVLSLYASGRTTGIVLDSGDGVXHTVPIYEGYALPHAISRLDLAGRDLT 652

Query: 173 KELETQLLEQCTVDTGAAKGQSLPSVMGSVPEGVLEDIKVRTCFVS-DLKRGLQIQAAKF 231
             L   L E+    T  A+ +            ++ DIK + C+V+ D ++ +Q  A+  
Sbjct: 653 DYLMKILTERGYSFTTTAERE------------IVRDIKEKLCYVALDFEQEMQTAASSS 796

Query: 232 NIDGNNERPTPPPNVDYPLDGEKILHVLGSIRDSVVEILFEQD---NEEKSVATLILDSL 288
           +++ + E P          DG+ I   +G+ R    E +F+      E         +S+
Sbjct: 797 SLEKSYELP----------DGQVI--TIGNERFRCPEAMFQPSFLGMESAGXHETTYNSI 940

Query: 289 LQCPIDTRKQLAENLVIIGGTSMLPGFLHRLLAEIRYLVEKPKYKKTLGTKNFRIHTPPA 348
           ++C +D RK L  N V+ GG++M PG   R+  EI  L           T   +I  PP 
Sbjct: 941 MKCDVDIRKDLYANTVLSGGSTMYPGIADRMQKEITALAPP--------TMKIKIIAPPE 1096

Query: 349 KANCVAWLGGAVFGALQDILGSRSISKEYYNQTG 382
           +   V W+GG++  +L        ISK+ Y+++G
Sbjct: 1097RKYSV-WIGGSILASLS-TFQQMWISKQEYDESG 1192
>39562
          Length = 1438

 Score =  105 bits (261), Expect = 4e-23,   Method: Compositional matrix adjust.
 Identities = 82/319 (25%), Positives = 150/319 (47%), Gaps = 4/319 (1%)
 Frame = -2

Query: 68   LKEFIHILYFRHLLVNPRDRRVVVIESVLCPSHFRETLTRVLFKYFEVPSVLLAPSHLMA 127
            +++  H  ++  L V P +  V++ E+ L P   RE +T+++F+ F  P++ +A   +++
Sbjct: 1416 MEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNSPAMYVAIQAVLS 1237

Query: 128  LLTLGINSAMVLDCGYRESLVLPIYEGIPILNCWGALPLGGKALHKELETQLLEQCTVDT 187
            L   G  + +VLD G   +  +PIYEG  + +    L L G+ L   L   L E+    T
Sbjct: 1236 LYASGRTTGIVLDSGDGVTHTVPIYEGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFT 1057

Query: 188  GAAKGQSLPSVMGSVPEGVLEDIKVRTCFVS-DLKRGLQIQAAKFNIDGNNERPTPPPNV 246
              A+ +            ++ DIK +  +V+ D ++ +   A+  +++ + E P      
Sbjct: 1056 TTAERE------------IVRDIKEKLDYVALDFEQEMLTAASSSSLEKSYELP------ 931

Query: 247  DYPLDGEKILHVLGSIRDSVVEILFEQD---NEEKSVATLILDSLLQCPIDTRKQLAENL 303
                DG+ I   +G+ R    E +F+      E   +     +S+++C +D RK L  N 
Sbjct: 930  ----DGQVI--TIGNERFRCPEAMFQPSFLGMESAGIHETTYNSIMKCDVDIRKDLYANT 769

Query: 304  VIIGGTSMLPGFLHRLLAEIRYLVEKPKYKKTLGTKNFRIHTPPAKANCVAWLGGAVFGA 363
            V+ GG++M PG   R+  EI  L           T   +I  PP +   V W+GG++  +
Sbjct: 768  VLSGGSTMYPGIADRMQKEITALAPP--------TMKIKIIAPPERKYSV-WIGGSILAS 616

Query: 364  LQDILGSRSISKEYYNQTG 382
            L        ISK+ Y+++G
Sbjct: 615  LS-TFQQMWISKQEYDESG 562
>00608
          Length = 1930

 Score = 60.5 bits (145), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 77/362 (21%), Positives = 145/362 (40%), Gaps = 23/362 (6%)
 Frame = +3

Query: 77  FRHLLVNPRDRRVVVIESVLCPSHFRETLTRVLFKYFEVPSVLLAPSHLMALLTLGIN-- 134
           F++L   P D   ++ E  L     RE    ++F+ F VP + +A   ++AL     +  
Sbjct: 51  FKYLRAEPEDHYFLLTEPPLNTPENREYTAEIMFESFNVPGLYIAVQAVLALAASWTSRN 230

Query: 135 ------SAMVLDCGYRESLVLPIYEGIPILNCWGALPLGGK-------ALHKELETQLLE 181
                 +  V+D G   + V+P+ EG  I +C   +P+ G+        L +E E  +  
Sbjct: 231 VGERTLTGTVIDSGDGVTHVIPVAEGYVIGSCIKHIPIAGRDITYFIQQLLREREVGIPP 410

Query: 182 QCTVDTGAAKGQSLPSVMGSVPEGVLEDIKVRTCFVSDLKRGLQIQAAKFNIDGNNERPT 241
           + +++T  A  +    V   + +   +     + ++   +    I    F++D   ER  
Sbjct: 411 EQSLETAKAIKERFSYVCPDIAKEFSKYDTDPSKWMKKYEGRNTISKQLFSVDVGYERFL 590

Query: 242 PPPNVDYPLDGEKILHVLGSIRDSVVEILFEQDNEEKSVATLILDSLLQCPIDTRKQLAE 301
            P         E   H   S  D  + I           + ++ D +  CPID R+ L +
Sbjct: 591 GP---------EIFFHPEFSNPDFTMPI-----------SDVVDDVIQNCPIDVRRGLYK 710

Query: 302 NLVIIGGTSMLPGFLHRLLAEIRYLVEKPKYKKTLGTKNFRIHTPPAKANCVA------- 354
           N+V+ GG++M   F  ++  +++ +V+  + K +      RI   P +   +        
Sbjct: 711 NIVLSGGSTMFRDFGRKIQRDVKRVVDG-RLKASEELSQGRIKPKPIEVQVITHHMQRYA 887

Query: 355 -WLGGAVFGALQDILGSRSISKEYYNQTGRIPDWCSLNNPPLEMMFDVGKAQPPLMKRAF 413
            W GG++  +  +       +K  Y++ G  P  C  +NP    M       PP   +A 
Sbjct: 888 VWFGGSMLASTPEFY-QVCHTKADYDEHG--PSICR-HNPVFGTM---A*TSPPATNKAT 1046

Query: 414 ST 415
           ST
Sbjct: 1047ST 1052
>36954
          Length = 892

 Score = 58.5 bits (140), Expect = 5e-09,   Method: Compositional matrix adjust.
 Identities = 49/208 (23%), Positives = 89/208 (42%), Gaps = 31/208 (14%)
 Frame = -1

Query: 6   GLGSGGEKTAVVIDLGEAFTKCGFAGETGPRCIIPSVI-----------KRAGMSKPIKV 54
           G+  G E  A+V D+G    + G+AGE  P+  IP+ +              G + P   
Sbjct: 832 GVYGGDEVGALVFDIGSYSFRAGYAGEDTPKAEIPTHVGVMEDIETTMDTDGGDAPPQPE 653

Query: 55  VQYNINT---------EELYSYLKE-FIHILYFRHLLVNPRDRRVVVIESVLCP------ 98
            +Y I+T           L S+LK+  +        +++    R +  ES L P      
Sbjct: 652 KKYLIDTVYMKHPRKGMHLNSFLKDGMVEDWDMFEKVIDYAYNRSIKSESCLHPLLMSEP 473

Query: 99  ----SHFRETLTRVLFKYFEVPSVLLAPSHLMALLTLGINSAMVLDCGYRESLVLPIYEG 154
                  RE LT ++F+ + +P+  L  + +++    G ++A++LD G   +  +P+Y+G
Sbjct: 472 AWNTKAKREKLTEIMFEKYNIPAFFLRKNSVLSAFANGRSTALILDSGATHTSAVPVYDG 293

Query: 155 IPILNCWGALPLGGKALHKELETQLLEQ 182
             +       PL G  + +E    + EQ
Sbjct: 292 YVLTQGIVKSPLAGDFIARECGLLMEEQ 209
>12322
          Length = 849

 Score = 55.5 bits (132), Expect = 4e-08,   Method: Compositional matrix adjust.
 Identities = 58/239 (24%), Positives = 104/239 (43%), Gaps = 5/239 (2%)
 Frame = +1

Query: 149 LPIYEGIPILNCWGALPLGGKALHKELETQLLEQCTVDTGAAKGQSLPSVMGSVPEGVLE 208
           +P+YEG  + +    + + G+ + + L   L ++         G  L +   +    V++
Sbjct: 13  VPVYEGFAMPHSIMRVDVAGRDVTRYLRLLLRKE---------GMDLHT---TAEFEVVK 156

Query: 209 DIKVRTCFVSDLKRGLQIQAAKFNIDGNNERPTPPPNVDYPL-DGEKILHVLGSIRDSVV 267
            IK RTC++S              I+   E       V Y L DG  +   +G  R    
Sbjct: 157 HIKERTCYLS--------------INPLKEESVDTEKVSYTLPDGNTV--EVGPARFRAP 288

Query: 268 EILFEQD---NEEKSVATLILDSLLQCPIDTRKQLAENLVIIGGTSMLPGFLHRLLAEIR 324
           E+LF  D    E + +  ++  S+ +  +D RK L  N+V+ GG+++  GF  RLL+E+ 
Sbjct: 289 ELLFRPDLIGEECEGIHEVLSYSIQKSDVDLRKTLYSNIVLSGGSTLFKGFGDRLLSEL- 465

Query: 325 YLVEKPKYKKTLGTKNFRIH-TPPAKANCVAWLGGAVFGALQDILGSRSISKEYYNQTG 382
                    K L  K+ +I  + P +     W+G ++  +L D      +SK  Y++ G
Sbjct: 466 ---------KKLAPKDIKIRISAPQERLYSTWIGXSILASL-DTFRKMWVSKREYHEEG 612
>02757
          Length = 1094

 Score = 53.9 bits (128), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 43/156 (27%), Positives = 75/156 (48%), Gaps = 5/156 (3%)
 Frame = -2

Query: 206 VLEDIKVRTCFVS-DLKRGLQIQAAKFNIDGNNERPTPPPNVDYPLDGEKILHVLGSIRD 264
           ++ DIK + C+V+ D ++ +   A+  +++ + E P          DG+ I   +G+ R 
Sbjct: 889 IVXDIKEKLCYVALDFEQEMATAASSSSLEKSYELP----------DGQVI--TIGNERF 746

Query: 265 SVVEILFEQD---NEEKSVATLILDSLLQCPIDTRKQLAENLVIIGGTSMLPGFLHRLLA 321
              E LF+      E   +     +S+++C +D RK L  N V+ GGT+M PG   R+  
Sbjct: 745 RCPESLFQPSFLGMESAGIHETTYNSIMKCDVDIRKDLYANTVLSGGTTMFPGIADRMQK 566

Query: 322 EIRYLVEKPKYKKTLGTKNFRIHTPPAKANCV-AWL 356
           EI  L   P++ +    +     +P A+  CV  WL
Sbjct: 565 EITALA--PQHHEDQXHR-----SPXAQVLCVDRWL 479
>13361
          Length = 1217

 Score = 43.9 bits (102), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 27/106 (25%), Positives = 51/106 (48%), Gaps = 12/106 (11%)
 Frame = +3

Query: 284 ILDSLLQ-CPIDTRKQLAENLVIIGGTSMLPGFLHRLLAEIRYLVEKPKYKKTLGTKNFR 342
           I+D+++Q CPID R+ L  N+V+ GG++M   F  RL  +I+  V+  + + +      R
Sbjct: 243 IVDNVIQNCPIDVRRHLYNNIVLSGGSTMFKDFGRRLQRDIKRSVDT-RLRISENLSEGR 419

Query: 343 IHTPPAKANCVA--------WLGGAVFGA---LQDILGSRSISKEY 377
           I   P     +         W GG++  +      +  +++  +EY
Sbjct: 420 IKPKPIDVQVITHHMQRYAVWFGGSMLASTPEFYQVCHTKAAYEEY 557
>01436
          Length = 2563

 Score = 42.4 bits (98), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 30/106 (28%), Positives = 52/106 (49%), Gaps = 3/106 (2%)
 Frame = +3

Query: 280 VATLILDSLLQCPIDTRKQLAENLVIIGGTSMLPGFLHRLLAEIRYL-VEKPKYKKTLGT 338
           VA L+ +++    +D R    +++V+ GG++M PG   RL  EI+ L +E+     T   
Sbjct: 270 VAELLFNTIQAADMDIRPDFYKHIVLSGGSTMYPGLPSRLEREIKQLYLERVLXGDTSRL 449

Query: 339 KNF--RIHTPPAKANCVAWLGGAVFGALQDILGSRSISKEYYNQTG 382
             F  RI  PP + + V +LGG+V   +        + +  Y + G
Sbjct: 450 SKFKIRIEDPPRRKHMV-FLGGSVXADIMKDKDDFWMMRSEYEEMG 584
>11487
          Length = 771

 Score = 41.2 bits (95), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 16/37 (43%), Positives = 24/37 (64%)
 Frame = -1

Query: 286 DSLLQCPIDTRKQLAENLVIIGGTSMLPGFLHRLLAE 322
           +S+++C +D RK L  N V+ GGT+M PG   R+  E
Sbjct: 759 NSIMKCDVDIRKDLYANTVLSGGTTMFPGIADRMQKE 649
>19721
          Length = 757

 Score = 35.8 bits (81), Expect = 0.037,   Method: Compositional matrix adjust.
 Identities = 14/30 (46%), Positives = 24/30 (80%), Gaps = 1/30 (3%)
 Frame = +3

Query: 284 ILDSLLQ-CPIDTRKQLAENLVIIGGTSML 312
           ++D+++Q CPID+R+ L  N+V+ GG+SM 
Sbjct: 651 VVDTVIQSCPIDSRRPLYNNIVLSGGSSMF 740
>27777
          Length = 622

 Score = 32.0 bits (71), Expect = 0.54,   Method: Compositional matrix adjust.
 Identities = 20/54 (37%), Positives = 29/54 (53%), Gaps = 1/54 (1%)
 Frame = -2

Query: 73  HILYFRHLLVNPRDRRVVVIESVLCPSHFRETLT-RVLFKYFEVPSVLLAPSHL 125
           +I +F+H +VN RD+    + S+    HF  TL   +LF Y EV  + L   HL
Sbjct: 270 YIFFFKHRIVNTRDK----LYSIYATFHFTSTLI*MILFYYLEV*IL*LTNIHL 121
>00154
          Length = 1049

 Score = 29.3 bits (64), Expect = 3.3,   Method: Compositional matrix adjust.
 Identities = 16/62 (25%), Positives = 28/62 (45%), Gaps = 1/62 (1%)
 Frame = -2

Query: 326 LVEKPKYKKTLGTKNFRIHTPPAKANCVAWLGGAV-FGALQDILGSRSISKEYYNQTGRI 384
           LV+  K+KK       ++H P   +  +AW G  +   +L     + + S  Y+    R+
Sbjct: 574 LVKNKKHKKQPSEALRKLHLPSFSSR*LAWSGHVIRHNSLSRTAQTNTTSHNYFPACSRM 395

Query: 385 PD 386
           PD
Sbjct: 394 PD 389
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|28626508|ref|NP_444305.2| RAS-homolog enriched in
brain [Mus musculus]
         (184 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

07580                                                                 117   3e-31
00858                                                                  98   2e-21
08428                                                                  79   1e-15
34468                                                                  74   4e-14
33374                                                                  56   8e-14
26536                                                                  72   2e-13
07465                                                                  72   2e-13
36482                                                                  68   2e-12
19006                                                                  64   3e-11
11728                                                                  63   6e-11
19046                                                                  62   1e-10
14456                                                                  60   4e-10
19656                                                                  57   5e-09
26083                                                                  56   1e-08
11257                                                                  54   3e-08
17511                                                                  54   3e-08
06994                                                                  39   4e-08
32723                                                                  51   2e-07
30760                                                                  51   3e-07
10708                                                                  39   8e-07
05468                                                                  49   1e-06
01398                                                                  48   3e-06
33380                                                                  46   7e-06
18509                                                                  45   1e-05
01095                                                                  45   2e-05
31291                                                                  42   1e-04
34597                                                                  41   3e-04
01972                                                                  36   6e-04
13901                                                                  40   8e-04
35581                                                                  39   0.002
34359                                                                  37   0.004
27191                                                                  37   0.005
31928                                                                  33   0.054
13745                                                                  32   0.12 
00552                                                                  32   0.19 
11142                                                                  28   2.4  
>07580
          Length = 921

 Score =  117 bits (294), Expect(2) = 3e-31,   Method: Compositional matrix adjust.
 Identities = 56/163 (34%), Positives = 105/163 (64%), Gaps = 4/163 (2%)
 Frame = +3

Query: 26  FVEGQFVDSYDPTIENTFTKLITVNGQEYHLQLVDTAGQDEYSIFPQTYSIDINGYILVY 85
             +G FV+ YDPTIE+++ K + V+GQ+  L+++DTAG ++++     Y  +  G++L Y
Sbjct: 120 LCKGIFVEKYDPTIEDSYRKQVEVDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFLLAY 299

Query: 86  SVTSIKSFEVIKVIHGKLLDMVGKVQIPIMLVGNKKDLHMERVISYEEGKALAESWNAAF 145
           S+T+  +F  ++ +  ++L +     +P++LVGNK DL  ERV+  ++G+ LA S++ AF
Sbjct: 300 SITAQSTFNDLQELREQILRVKDTDDVPMLLVGNKCDLEDERVVGKDQGQGLARSFSCAF 479

Query: 146 LESSAKE----NQTAVDVFKRIILEAEKIDGAASQGKSSCSVM 184
           LE+SAK     N+  +D+ ++I  ++ +  G  ++ K SC+V+
Sbjct: 480 LETSAKARINVNEIFMDLVRQINKKSPEQSGKRTKSKKSCTVL 608

 Score = 33.9 bits (76), Expect(2) = 3e-31,   Method: Compositional matrix adjust.
 Identities = 14/24 (58%), Positives = 19/24 (79%)
 Frame = +2

Query: 8  KIAILGYRSVGKSSLTIQFVEGQF 31
          K+ +LG   VGKS+LT+QFV+G F
Sbjct: 65 KLVVLGSGGVGKSALTVQFVQGDF 136
>00858
          Length = 1658

 Score = 98.2 bits (243), Expect = 2e-21,   Method: Compositional matrix adjust.
 Identities = 52/148 (35%), Positives = 88/148 (59%)
 Frame = -2

Query: 19   KSSLTIQFVEGQFVDSYDPTIENTFTKLITVNGQEYHLQLVDTAGQDEYSIFPQTYSIDI 78
            KS+LTIQ  +  FV+ YDPT E++  K + ++G+   L ++DTAGQ+E S          
Sbjct: 1552 KSALTIQLXQNHFVEEYDPTXEDSXRKQVVIDGETCLLDILDTAGQEEXSAMRDQCMRTG 1373

Query: 79   NGYILVYSVTSIKSFEVIKVIHGKLLDMVGKVQIPIMLVGNKKDLHMERVISYEEGKALA 138
             G++ V++V ++KSFE I     ++  +    ++P++LVGNK DL + R +   +GK +A
Sbjct: 1372 EGFLCVFAVXNLKSFEDINQYREQIKRVKDADEVPMVLVGNKVDLPI-RNVEQRQGKHMA 1196

Query: 139  ESWNAAFLESSAKENQTAVDVFKRIILE 166
            E ++  ++E+SAK  Q   D F  ++ E
Sbjct: 1195 ELYHIPYVETSAKTRQGVDDAFYTLVRE 1112
>08428
          Length = 1109

 Score = 78.6 bits (192), Expect = 1e-15,   Method: Compositional matrix adjust.
 Identities = 53/158 (33%), Positives = 85/158 (53%), Gaps = 1/158 (0%)
 Frame = -3

Query: 3    QSKSRKIAILGYRSVGKSSLTIQFVEGQFVDSYDPTIENTF-TKLITVNGQEYHLQLVDT 61
            Q +  K+ +LG   VGKSS+ ++FV G +  S + TI  +F +K + V+G  Y  Q+ DT
Sbjct: 1080 QMRDVKVCLLGDSGVGKSSIVLRFVTGSYRPSQESTIGASFMSKSLVVDGAGYRFQIWDT 901

Query: 62   AGQDEYSIFPQTYSIDINGYILVYSVTSIKSFEVIKVIHGKLLDMVGKVQIPIMLVGNKK 121
            AGQ+++      Y       ++VY VT  ++F+ +K    +L    G   I + + GNK 
Sbjct: 900  AGQEKFRALAPMYYRGAAAAVIVYDVTRPRTFKSVKSWIQELRSF-GPPNIVLAIAGNKC 724

Query: 122  DLHMERVISYEEGKALAESWNAAFLESSAKENQTAVDV 159
            DL   R +  ++ +  A S +A F E+SA    TAV+V
Sbjct: 723  DLEELREVVEKDAQEYASSISAIFGETSA---MTAVNV 619
>34468
          Length = 1502

 Score = 73.6 bits (179), Expect = 4e-14,   Method: Compositional matrix adjust.
 Identities = 52/157 (33%), Positives = 85/157 (54%), Gaps = 3/157 (1%)
 Frame = +1

Query: 3   QSKSRKIAILGYRSVGKSSLTIQFVEGQFVDSYDPTIENTFT-KLITVNGQEYHLQLVDT 61
           Q +  KI ++G  +VGK+ LT +F  G+F D  + TI   F  K I V+ +   LQL DT
Sbjct: 484 QRRIFKIIVIGDSNVGKTCLTYRFCLGKFPDKTEATIGVDFREKSIQVDSEHLKLQLWDT 663

Query: 62  AGQDEY-SIFPQTYSIDINGYILVYSVTSIKSFEVIKVIHGKLLDMVGKVQIPIMLVGNK 120
           AGQ+ +     Q Y  +++  + VY +T + SFE +     +         IP +LVGNK
Sbjct: 664 AGQERFRKSMVQHYYRNVHAVVFVYDMTKMSSFENMPAWIEECDRHNLTKYIPRILVGNK 843

Query: 121 KDLHMERV-ISYEEGKALAESWNAAFLESSAKENQTA 156
            D+ +ER+ ++    +  A++ N    E+SAK+++ A
Sbjct: 844 CDV-VERIAVNTNLAQKFADAHNMPLFETSAKDDEKA 951
>33374
          Length = 489

 Score = 56.2 bits (134), Expect(2) = 8e-14,   Method: Compositional matrix adjust.
 Identities = 38/117 (32%), Positives = 59/117 (50%)
 Frame = +1

Query: 43  FTKLITVNGQEYHLQLVDTAGQDEYSIFPQTYSIDINGYILVYSVTSIKSFEVIKVIHGK 102
            T+ + ++      ++ DTAGQ+ Y      Y       I+VY +T+  +F   K    K
Sbjct: 142 LTQTVCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNQDTFGRAKT-WVK 318

Query: 103 LLDMVGKVQIPIMLVGNKKDLHMERVISYEEGKALAESWNAAFLESSAKENQTAVDV 159
            L       I I L GNK DL  +R++ +EE +A AE  +  F+E+SAK   TA++V
Sbjct: 319 ELQRQASPNIVIALAGNKADLANKRMVEFEEAQAYAEENSLLFMETSAK---TAMNV 480

 Score = 36.6 bits (83), Expect(2) = 8e-14,   Method: Compositional matrix adjust.
 Identities = 17/36 (47%), Positives = 25/36 (69%)
 Frame = +2

Query: 8  KIAILGYRSVGKSSLTIQFVEGQFVDSYDPTIENTF 43
          K+ +LG  +VGKSSL ++FV+GQF +  + TI   F
Sbjct: 35 KLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAF 142
>26536
          Length = 829

 Score = 71.6 bits (174), Expect = 2e-13,   Method: Compositional matrix adjust.
 Identities = 41/134 (30%), Positives = 70/134 (52%), Gaps = 8/134 (5%)
 Frame = +2

Query: 58  LVDTAGQDEYSIFPQTYSIDINGYILVYSVTSIKSFEVIKVIHGKLLDMVGKVQIPIMLV 117
            +DTAGQ+EYS   + Y+   +G+I+VYSVT + SF+  + +   L     +  I  +L 
Sbjct: 140 FLDTAGQEEYSSMREHYTRSGDGFIVVYSVTDVTSFQEAEAVFRWLTRFQDETSIHAVLC 319

Query: 118 GNKKDLHMERVISYEEGKALAESWNAAFLESSAKENQTAVDVFKRIILEAEK-------- 169
           GNK DL  +R ++ EEG+ +A+     + E+SAK       V+  ++    +        
Sbjct: 320 GNKTDLTSDRKVTPEEGRKMADRLGMLYFETSAKTGDNVSQVYHGLLRSIPRSGTDYKIV 499

Query: 170 IDGAASQGKSSCSV 183
           + G+   GKSS ++
Sbjct: 500 MLGSGGVGKSSLTI 541

 Score = 57.4 bits (137), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 28/53 (52%), Positives = 40/53 (75%), Gaps = 1/53 (1%)
 Frame = +2

Query: 1   MPQSKSR-KIAILGYRSVGKSSLTIQFVEGQFVDSYDPTIENTFTKLITVNGQ 52
           +P+S +  KI +LG   VGKSSLTI+F +  F+D YDPTIE+++ K+I V+GQ
Sbjct: 467 IPRSGTDYKIVMLGSGGVGKSSLTIRFTQDTFLDVYDPTIEDSYRKMIQVSGQ 625
>07465
          Length = 1103

 Score = 71.6 bits (174), Expect = 2e-13,   Method: Compositional matrix adjust.
 Identities = 47/143 (32%), Positives = 73/143 (51%), Gaps = 1/143 (0%)
 Frame = +3

Query: 20  SSLTIQFVEGQFVDSYDPTIENTF-TKLITVNGQEYHLQLVDTAGQDEYSIFPQTYSIDI 78
           SS+  ++ +G F   Y  TI   F  + I V G++  L L DTAGQ+E+    + Y    
Sbjct: 240 SSMIQRYCKGIFTKDYKKTIGVDFLERQIEVGGEDVRLMLWDTAGQEEFDAITKAYYRGA 419

Query: 79  NGYILVYSVTSIKSFEVIKVIHGKLLDMVGKVQIPIMLVGNKKDLHMERVISYEEGKALA 138
              +L +S     SFE ++    K+ D VG  +I +++V NK DL  + V+  EE + LA
Sbjct: 420 QACVLAFSTVDRDSFEALETWKRKVEDEVG--EIGMVIVQNKIDLIDDAVVRPEEAENLA 593

Query: 139 ESWNAAFLESSAKENQTAVDVFK 161
           +     F  +S KEN    +VF+
Sbjct: 594 KKLRLRFYRTSVKENMNVDEVFR 662
>36482
          Length = 686

 Score = 68.2 bits (165), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 36/131 (27%), Positives = 71/131 (54%)
 Frame = +2

Query: 22  LTIQFVEGQFVDSYDPTIENTFTKLITVNGQEYHLQLVDTAGQDEYSIFPQTYSIDINGY 81
           LT++F+  +F+  Y PT+E+ +     +   +  L+++DTAGQ  Y  + + Y++  + +
Sbjct: 2   LTVRFLTRRFIGEYCPTLESVYKYHTVIEDDDVRLEILDTAGQGTYP-WKEGYALWADCF 178

Query: 82  ILVYSVTSIKSFEVIKVIHGKLLDMVGKVQIPIMLVGNKKDLHMERVISYEEGKALAESW 141
           + VYS+   +S+E +  +  ++  +     +  +L  NK DL  +R ++ +EG+ LAE  
Sbjct: 179 VFVYSINDRQSYEELVQVKRQVESVRKSTSLTAVLAANKTDLLHDRQVTQKEGEDLAEEI 358

Query: 142 NAAFLESSAKE 152
                E SA E
Sbjct: 359 GCRLYEVSASE 391
>19006
          Length = 568

 Score = 64.3 bits (155), Expect = 3e-11,   Method: Compositional matrix adjust.
 Identities = 41/118 (34%), Positives = 64/118 (54%), Gaps = 1/118 (0%)
 Frame = -2

Query: 8   KIAILGYRSVGKSSLTIQFVEGQFVDSYDPTIENTFTKLITVNGQEYHLQLVDTAGQDEY 67
           K+ I+G  + GK+ L I F + QF + Y PT+   +   I V+ ++  L L DTAGQ++Y
Sbjct: 432 KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDSKQVELALWDTAGQEDY 253

Query: 68  S-IFPQTYSIDINGYILVYSVTSIKSFEVIKVIHGKLLDMVGKVQIPIMLVGNKKDLH 124
             + P +Y  D +  ++ +S+ S  S E I       +       +PI+LVGNKKDL 
Sbjct: 252 DRLRPLSYP-DTDVILMCFSIDSPDSLENIPEKWTPEVRHFCP-NVPIILVGNKKDLR 85
>11728
          Length = 635

 Score = 63.2 bits (152), Expect = 6e-11,   Method: Compositional matrix adjust.
 Identities = 48/159 (30%), Positives = 80/159 (50%), Gaps = 16/159 (10%)
 Frame = -1

Query: 8   KIAILGYRSVGKSSLTIQFVEGQFVDSYDPTIENTFTKLITVNGQEYHLQLVDTAGQDEY 67
           K  ++G  +VGK+ L I +    F   Y PT+ + ++  + V+ +  +L L DTAGQ++Y
Sbjct: 485 KCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDSKPINLGLWDTAGQEDY 306

Query: 68  S-IFPQTYSIDINGYILVYSVTSIKSFEVIKVIHGKLLDMVGK--VQIPIMLVGNKKDLH 124
             + P +Y    + +++ +S+ S  SFE +K    K    V       PI+LVG K DL 
Sbjct: 305 DRLRPLSYP-QTDVFLICFSLISPASFENVK---AKWYPEVSHHCPNTPIILVGTKLDLR 138

Query: 125 MER------------VISYEEGKALAESWNAA-FLESSA 150
            ++             I+Y +G A+A+   A  +LE SA
Sbjct: 137 EDKETIEKLKEKKLAPITYPQGLAMAKDIGAGKYLECSA 21
>19046
          Length = 445

 Score = 62.4 bits (150), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 32/96 (33%), Positives = 56/96 (58%)
 Frame = -2

Query: 64  QDEYSIFPQTYSIDINGYILVYSVTSIKSFEVIKVIHGKLLDMVGKVQIPIMLVGNKKDL 123
           Q+E+S   + Y    +G++LV+SVT  +SFE +   H ++L +  +   P++L  NK DL
Sbjct: 444 QEEFSAMREQYMRKGDGFLLVFSVTDFRSFENMANFHTQILRVKDRDSYPMILCANKVDL 265

Query: 124 HMERVISYEEGKALAESWNAAFLESSAKENQTAVDV 159
             +R +S E+ + LA      ++E+SAK+    VD+
Sbjct: 264 VHQRKVSEEQVRDLATRLRIPYIETSAKDPPLNVDL 157
>14456
          Length = 1867

 Score = 60.5 bits (145), Expect = 4e-10,   Method: Composition-based stats.
 Identities = 44/148 (29%), Positives = 73/148 (49%), Gaps = 4/148 (2%)
 Frame = -1

Query: 17   VGKSSLTIQFVEGQFVDSYDPTIENTF-TKLITVNGQEYHLQLVDTAGQDEYSIFPQTYS 75
            VGKSSL  +FV  +F      TI   F  K + V+ + Y +Q+ DTAGQ+ +      + 
Sbjct: 1108 VGKSSLMNRFVSNKFDAQSFHTIGVEFLNKDVVVDDETYTMQIWDTAGQERFKSLRTPFY 929

Query: 76   IDINGYILVYSVTSIKSFEVIKVIHGKLL---DMVGKVQIPIMLVGNKKDLHMERVISYE 132
               +  +L +SV S++SF  + +   + L   D+   V  P +++GNK D+   +V + E
Sbjct: 928  RGADCCLLTFSVDSMQSFRNLSMWRKEFLYYADIQDGVTFPFVVLGNKIDVEGRQVTNEE 749

Query: 133  EGKALAESWNAAFLESSAKENQTAVDVF 160
                   + NA + E+SAK+       F
Sbjct: 748  ARSWCTANSNAPYFETSAKDATNVEKAF 665
>19656
          Length = 428

 Score = 57.0 bits (136), Expect = 5e-09,   Method: Compositional matrix adjust.
 Identities = 33/95 (34%), Positives = 54/95 (56%), Gaps = 5/95 (5%)
 Frame = +3

Query: 8   KIAILGYRSVGKSSLTIQFVEGQFVDSYDPTIENTFTKLITVNGQEYHLQLVDTAGQDEY 67
           K  ++G  +VGK+ L I +    F   Y PT+ + ++  + V+G+  +L L DTAGQ++Y
Sbjct: 117 KCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGRPVNLGLWDTAGQEDY 296

Query: 68  S-----IFPQTYSIDINGYILVYSVTSIKSFEVIK 97
                  +PQT   D+  ++L +SV S  SFE I+
Sbjct: 297 DRLRPLSYPQT---DV--FLLCFSVASPASFENIR 386
>26083
          Length = 432

 Score = 55.8 bits (133), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 41/117 (35%), Positives = 63/117 (53%), Gaps = 4/117 (3%)
 Frame = +1

Query: 8   KIAILGYRSVGKSSLTIQFVEGQFVDSYDPTIENTF-TKLITVNGQEYHLQLVDTAGQDE 66
           K+  LG +SVGK+SL  +F+   F ++Y  TI   F +K + +  +   LQL DTAGQ+ 
Sbjct: 82  KLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTIRLQLWDTAGQER 261

Query: 67  YSIFPQTYSIDINGYILVYSVTSIKSFEVIKVIHGKLLDMVGKVQ---IPIMLVGNK 120
           +     +Y  D +  ++VY +T+  SF        K +D V   +   + IMLVGNK
Sbjct: 262 FRSLIPSYIRDSSVAVVVYDITNANSFHQT----SKWIDDVRTERGSDVIIMLVGNK 420
>11257
          Length = 1102

 Score = 54.3 bits (129), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 32/131 (24%), Positives = 66/131 (50%), Gaps = 4/131 (3%)
 Frame = -2

Query: 45   KLITVNGQEYHLQLVDTAGQDEYSIFPQTYSIDINGYILVYSVTSIKSFEVIKVIHGKLL 104
            K + V+G+ + +Q+ DTAGQ+ Y      +    +  +L +SV ++KS + +   + + +
Sbjct: 1053 KDVVVDGETFTMQIWDTAGQERYKSLRTPFYRGTDCCLLTFSVDNLKSLQSLSDWYDEFV 874

Query: 105  ---DMVGKVQIPIMLVGNKKDLHMERVISYEEGKALAESW-NAAFLESSAKENQTAVDVF 160
               D+      P +++GNK D+  ER +S E+      +  N  + E+SAK++      F
Sbjct: 873  NYADIQDSASFPFVIIGNKADIE-EREVSSEDAYNWCRTHGNLPYFETSAKDSLNVQQAF 697

Query: 161  KRIILEAEKID 171
              ++    ++D
Sbjct: 696  LAVVRRLREMD 664
>17511
          Length = 483

 Score = 53.9 bits (128), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 37/120 (30%), Positives = 59/120 (49%), Gaps = 4/120 (3%)
 Frame = -3

Query: 8   KIAILGYRSVGKSSLTIQFVEGQFVDSYDPTIENTF-TKLITVNGQEYHLQLVDTAGQDE 66
           K+ ILG   VGK+SL  Q+V  +F + Y  TI   F TK + V+ +   +Q+ DTAGQ+ 
Sbjct: 361 KVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQIWDTAGQER 182

Query: 67  YSIFPQTYSIDINGYILVYSVTSIKSFEVIKVIHGKLLDMVGKV---QIPIMLVGNKKDL 123
           +      +    +  +LV+ VT   +F  +     + L           P +++GNK DL
Sbjct: 181 FQSLGVAFYRGADCCVLVFDVTMPNTFRSLDSWRDEFLIQASPRDPENFPFVVIGNKIDL 2
>06994
          Length = 429

 Score = 38.5 bits (88), Expect(2) = 4e-08,   Method: Compositional matrix adjust.
 Identities = 15/29 (51%), Positives = 24/29 (82%)
 Frame = +1

Query: 35  YDPTIENTFTKLITVNGQEYHLQLVDTAG 63
           YDPTIE+++ K + V+GQ+  L+++DTAG
Sbjct: 142 YDPTIEDSYRKQVEVDGQQCMLEILDTAG 228

 Score = 35.0 bits (79), Expect(2) = 4e-08,   Method: Compositional matrix adjust.
 Identities = 15/29 (51%), Positives = 22/29 (75%)
 Frame = +3

Query: 5  KSRKIAILGYRSVGKSSLTIQFVEGQFVD 33
          +  K+ +LG   VGKS+LT+QFV+G FV+
Sbjct: 51 REYKLVVLGSGGVGKSALTVQFVQGIFVE 137
>32723
          Length = 384

 Score = 51.2 bits (121), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 35/101 (34%), Positives = 51/101 (50%), Gaps = 1/101 (0%)
 Frame = +2

Query: 64  QDEYSIFPQTYSIDINGYILVYSVTSIKSFEVI-KVIHGKLLDMVGKVQIPIMLVGNKKD 122
           Q+ +    Q+Y    N  ILVY V S +S+E + + IH   +++    ++   LVGNK D
Sbjct: 2   QERFRSITQSYYRSANALILVYDVCSQQSYESLPQWIHE--IELYAGTKVLAFLVGNKID 175

Query: 123 LHMERVISYEEGKALAESWNAAFLESSAKENQTAVDVFKRI 163
              +R I    GK  AE +   FLE+SAKE      +F  I
Sbjct: 176 QTDKREIPTHIGKEFAERYEMRFLETSAKEADNVEKLFSTI 298
>30760
          Length = 596

 Score = 50.8 bits (120), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 47/152 (30%), Positives = 69/152 (45%), Gaps = 5/152 (3%)
 Frame = -1

Query: 8   KIAILGYRSVGKSSLTIQFVE--GQFVDSYDPTIE-NTFTKLITV--NGQEYHLQLVDTA 62
           K  + G   VGKSS+   F      F  +Y  T       KL+ +  +  +  L L D+A
Sbjct: 524 KCIVTGDSGVGKSSICQVFHSDSAHFPKNYSMTTGVEVLVKLVNIPDSRDQVELYLFDSA 345

Query: 63  GQDEYSIFPQTYSIDINGYILVYSVTSIKSFEVIKVIHGKLLDMVGKVQIPIMLVGNKKD 122
           G++ +S     +    +  ++VY VT   SF        ++        IP +LV NK D
Sbjct: 344 GKEIFSENVTKFWDQPSVVMVVYDVTDETSFSGCVRWLERVRAAKPNTVIPGVLVANKTD 165

Query: 123 LHMERVISYEEGKALAESWNAAFLESSAKENQ 154
           L   R +S +EGK LA+S    + E SAKE Q
Sbjct: 164 LDERRRVSRKEGKDLAQSHGLEYFECSAKEMQ 69
>10708
          Length = 2775

 Score = 39.3 bits (90), Expect(2) = 8e-07,   Method: Compositional matrix adjust.
 Identities = 23/62 (37%), Positives = 35/62 (56%), Gaps = 13/62 (20%)
 Frame = -3

Query: 112  IPIMLVGNKKDLH------------MERVISYEEGKALAESWNA-AFLESSAKENQTAVD 158
            +PI+LVGNKKDL              +  +  +EG+A++E  NA ++LE SAK  +   +
Sbjct: 2551 VPIILVGNKKDLRNDENTKRELMKMKQEPVRLDEGRAMSEKINAYSYLECSAKTKEGVRE 2372

Query: 159  VF 160
            VF
Sbjct: 2371 VF 2366

 Score = 29.6 bits (65), Expect(2) = 8e-07,   Method: Compositional matrix adjust.
 Identities = 17/47 (36%), Positives = 27/47 (57%), Gaps = 1/47 (2%)
 Frame = -2

Query: 52   QEYHLQLVDTAGQDEYS-IFPQTYSIDINGYILVYSVTSIKSFEVIK 97
            Q+  L L DTAGQ++Y  + P +Y  D +  ++ +S+ S  S E I 
Sbjct: 2729 QQVELALWDTAGQEDYDRLRPLSYP-DTDVILMCFSIDSPDSLENIP 2592
>05468
          Length = 1558

 Score = 48.9 bits (115), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 43/156 (27%), Positives = 73/156 (46%), Gaps = 10/156 (6%)
 Frame = -3

Query: 8    KIAILGYRSVGKSSLTIQFVEGQFVDSYDPTIENTFT-KLITVNGQEY-HLQLVDTAGQD 65
            KI ++G    GK+S+  ++V   F   Y  TI   F  K++  +      LQL D AGQ+
Sbjct: 1535 KILVIGELGTGKTSIIKRYVHQFFSQHYRATIGVDFALKVLNWDADTLIRLQLWDIAGQE 1356

Query: 66   EYSIFPQTYSIDINGYILVYSVTSIKSFEVIKVIHGKLLDMVGKVQ------IPIMLVGN 119
             +    + Y  +  G  +V+ VT   +F+ +        D+  KVQ      +P +L+ N
Sbjct: 1355 RFGNMTRVYYKEAVGAFVVFDVTRASTFDAVTKWKN---DLDSKVQLADGSPVPCVLLAN 1185

Query: 120  KKDLHMERVI--SYEEGKALAESWNAAFLESSAKEN 153
            K D   E ++  + +  +  +E     + E+SAKEN
Sbjct: 1184 KCDQAKEGLVNNTSQMDEFCSEKGFIGWYETSAKEN 1077
>01398
          Length = 1421

 Score = 47.8 bits (112), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 27/100 (27%), Positives = 50/100 (50%)
 Frame = -2

Query: 64   QDEYSIFPQTYSIDINGYILVYSVTSIKSFEVIKVIHGKLLDMVGKVQIPIMLVGNKKDL 123
            Q+ +    ++Y  +  G I+VY +T   +FE +K  + +  + +   +   +++G+K D 
Sbjct: 1420 QERFRSITRSYYRNSVGVIIVYDITKRSTFENLKQWYEEARNHIEPHKAIFLVLGHKSDR 1241

Query: 124  HMERVISYEEGKALAESWNAAFLESSAKENQTAVDVFKRI 163
               R ++  EG+  AE     F E+SAK      DVF +I
Sbjct: 1240 EDARQVTAREGRRFAEMHGLKFFETSAKSGHNIEDVFAQI 1121
>33380
          Length = 282

 Score = 46.2 bits (108), Expect = 7e-06,   Method: Compositional matrix adjust.
 Identities = 28/79 (35%), Positives = 41/79 (51%), Gaps = 6/79 (7%)
 Frame = +3

Query: 56  LQLVDTAGQDEYSIFPQTYSIDINGYILVYSVTSIKSFEVIKVIHGKLLDMVGKVQI--- 112
           LQ+ DTAGQ+ Y      Y     G+IL+Y VT+ +SF  ++       D   +++    
Sbjct: 66  LQIWDTAGQERYRTITTAYYRGAMGFILMYDVTNEESFNAVQ-------DWCTQIKTYSW 224

Query: 113 ---PIMLVGNKKDLHMERV 128
               ++LVGNK DL  ERV
Sbjct: 225 DNAQVVLVGNKCDLEDERV 281
>18509
          Length = 625

 Score = 45.4 bits (106), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 26/80 (32%), Positives = 45/80 (56%), Gaps = 9/80 (11%)
 Frame = -3

Query: 111 QIPIMLVGNKKDLHMERVISYEEGKALAESWNAAFLESSAKENQTAVDVFKRIILE---- 166
           ++P++LVGNK DL + R +   +GK +AE ++  ++E+SAK  Q   D F  ++ E    
Sbjct: 530 EVPMVLVGNKVDLPI-RNVEQRQGKHMAELYHIPYVETSAKTRQGVDDAFYTLVREIRKY 354

Query: 167 AEKIDGAASQ-----GKSSC 181
            E+ DG   +     G+ +C
Sbjct: 353 KERKDGRRKRER*GSGRVNC 294
>01095
          Length = 1745

 Score = 45.1 bits (105), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 31/90 (34%), Positives = 46/90 (51%)
 Frame = -1

Query: 83   LVYSVTSIKSFEVIKVIHGKLLDMVGKVQIPIMLVGNKKDLHMERVISYEEGKALAESWN 142
            +VY +T+  +F   K    K L       I I L GNK DL  +R++ +EE +A AE  +
Sbjct: 1745 VVYDITNQDTFGRAKTWV-KELQRQASPNIVIALAGNKADLANKRMVEFEEAQAYAEENS 1569

Query: 143  AAFLESSAKENQTAVDVFKRIILEAEKIDG 172
              F+E+SAK      D+F  I  +  K +G
Sbjct: 1568 LLFMETSAKTAMNVNDIFLAIAKKLPKNEG 1479
>31291
          Length = 446

 Score = 42.4 bits (98), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 39/144 (27%), Positives = 69/144 (47%), Gaps = 15/144 (10%)
 Frame = -1

Query: 56  LQLVDTAGQDEYS-IFPQTYSIDINGYILVYSVTSIKSFEVIKVIHGKLLDMVGKVQIPI 114
           LQL DTAGQ++Y  + P  Y  + + ++L +S+ S  S + +KV     +       +PI
Sbjct: 446 LQLWDTAGQEDYDRLRPLAYP-NTDVFMLXFSLMSEASMKNVKVKWYPEIRH-HDPHVPI 273

Query: 115 MLVGNKKDLHMER------------VISYEEGKALAESWNAA-FLESSAKENQTAVDVFK 161
           +LVG K DL  ++             +S  +G  LA++  A  + E S+K  +     F+
Sbjct: 272 VLVGTKLDLRQDKEAVRKLRSSRQDPVSSNQGNDLAKAIKAKRYFECSSKTQENLKTAFE 93

Query: 162 RIILEAEKIDGAAS-QGKSSCSVM 184
             +  A  +DG  + + K  C ++
Sbjct: 92  ETVRVALNMDGQNNKRPKPKCVLL 21
>34597
          Length = 773

 Score = 40.8 bits (94), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 24/64 (37%), Positives = 39/64 (60%), Gaps = 1/64 (1%)
 Frame = -2

Query: 91  KSFE-VIKVIHGKLLDMVGKVQIPIMLVGNKKDLHMERVISYEEGKALAESWNAAFLESS 149
           KSFE ++K +    +D      +  M++GNK D+  +RV+S E G+A+A   +  F+E+S
Sbjct: 712 KSFENIVKWLRN--IDEHANEDVEKMILGNKCDMTDKRVVSKERGEAIAREHSIRFMETS 539

Query: 150 AKEN 153
           AK N
Sbjct: 538 AKSN 527
>01972
          Length = 2359

 Score = 35.8 bits (81), Expect(2) = 6e-04,   Method: Compositional matrix adjust.
 Identities = 28/96 (29%), Positives = 48/96 (50%), Gaps = 2/96 (2%)
 Frame = +3

Query: 60  DTAGQDEYSIFPQTYSIDINGYILVYSVTSIKSFEVIKVIHGKLLDMVGKVQIPIMLVGN 119
           DTAGQ+++      Y I     ++++ VTS  +++ +   H  L+ +     IPI+L GN
Sbjct: 465 DTAGQEKFGGLRDGYYIQGQCAVIMFDVTSRVTYKNVPNWHRDLVRVCE--NIPIVLCGN 638

Query: 120 KKDLHMERVISYEEGKALA--ESWNAAFLESSAKEN 153
           K D+   +V    + KA+      N  + + SAK N
Sbjct: 639 KVDIKDRKV----KAKAIVFHRKKNLQYYDISAKSN 734

 Score = 23.1 bits (48), Expect(2) = 6e-04,   Method: Compositional matrix adjust.
 Identities = 12/40 (30%), Positives = 21/40 (52%)
 Frame = +1

Query: 1   MPQSKSRKIAILGYRSVGKSSLTIQFVEGQFVDSYDPTIE 40
           M Q  + K+ ++G   VGK++   + V G+F  +  P  E
Sbjct: 286 MEQEPTFKLVLVGDGGVGKTTFVKRHVTGEFEKNMLPHWE 405
>13901
          Length = 962

 Score = 39.7 bits (91), Expect = 8e-04,   Method: Compositional matrix adjust.
 Identities = 26/89 (29%), Positives = 47/89 (52%), Gaps = 2/89 (2%)
 Frame = -3

Query: 8   KIAILGYRSVGKSSLTIQFVEGQFVDSYDPTIENTFT-KLITVNGQ-EYHLQLVDTAGQD 65
           K+ I+G  +VGK+S   ++V   F   Y  TI   F  K+I  + +    LQL D AGQ+
Sbjct: 282 KVIIIGDPTVGKTSFVQRYVNDSFRRDYKMTIGVDFALKVIRWSDKCNIKLQLWDIAGQE 103

Query: 66  EYSIFPQTYSIDINGYILVYSVTSIKSFE 94
            ++   + Y  D +  I+++ +T   +++
Sbjct: 102 RFTSMTRVYYKDAHACIVMFDLTQKNTYQ 16
>35581
          Length = 364

 Score = 38.5 bits (88), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 26/82 (31%), Positives = 38/82 (46%), Gaps = 4/82 (4%)
 Frame = +2

Query: 8   KIAILGYRSVGKSSLTIQFVEGQFVDSYDPTIENTFTKLITV----NGQEYHLQLVDTAG 63
           K  +LG   VGK+ L  +    +F+DS  P    T   L+T     +G    + L DTAG
Sbjct: 50  KCVLLGDAGVGKTCLLNRLATDKFLDS--PLTSLTTASLLTTVTLTSGVMASVDLWDTAG 223

Query: 64  QDEYSIFPQTYSIDINGYILVY 85
           Q+ Y     +Y  D    ++VY
Sbjct: 224 QERYRSLTSSYYRDTKAVLIVY 289
>34359
          Length = 1042

 Score = 37.4 bits (85), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 22/74 (29%), Positives = 38/74 (51%)
 Frame = +3

Query: 55  HLQLVDTAGQDEYSIFPQTYSIDINGYILVYSVTSIKSFEVIKVIHGKLLDMVGKVQIPI 114
              + DTAGQ+++      Y I     I+++ VTS  +++ +   H  L+ +     IPI
Sbjct: 198 RFNVWDTAGQEKFGGLRDGYYIQGTCAIIMFDVTSRVTYKNVPNWHRDLVRVCE--NIPI 371

Query: 115 MLVGNKKDLHMERV 128
           +L GNK D+   +V
Sbjct: 372 VLCGNKVDIKDRKV 413
>27191
          Length = 443

 Score = 36.6 bits (83), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 22/79 (27%), Positives = 38/79 (48%), Gaps = 1/79 (1%)
 Frame = +1

Query: 19 KSSLTIQFVEGQFVDSYDPTIENTFT-KLITVNGQEYHLQLVDTAGQDEYSIFPQTYSID 77
          K+ L   F E +F   Y PT+   +  K+ TVNG +  + + D +G +EY          
Sbjct: 1  KTCLIKHFCESKFNQGYQPTVGVDYGFKIQTVNGVDMRVHMWDLSGSNEYLDVRNELYTG 180

Query: 78 INGYILVYSVTSIKSFEVI 96
           +   +V+ V++  SFE +
Sbjct: 181SDAIFIVFDVSNTPSFEAL 237
>31928
          Length = 429

 Score = 33.5 bits (75), Expect = 0.054,   Method: Compositional matrix adjust.
 Identities = 23/88 (26%), Positives = 46/88 (52%), Gaps = 4/88 (4%)
 Frame = +2

Query: 38  TIENTFTKLI-TVNGQEYHLQLVDTAG---QDEYSIFPQTYSIDINGYILVYSVTSIKSF 93
           TIE+ +T +I T  G +  +++ DT     +      P+ Y    +G++LVY  TS +SF
Sbjct: 53  TIEDIYTAVIETDRGVKEKVRIFDTGAAALETTEGDLPKHYLNFPDGFVLVYDTTSWESF 232

Query: 94  EVIKVIHGKLLDMVGKVQIPIMLVGNKK 121
             +  +   +     K ++ ++++GNK+
Sbjct: 233 RRLDKLKKDIDKHRDKREVHMIVIGNKE 316
>13745
          Length = 1045

 Score = 32.3 bits (72), Expect = 0.12,   Method: Compositional matrix adjust.
 Identities = 23/75 (30%), Positives = 36/75 (48%), Gaps = 4/75 (5%)
 Frame = +2

Query: 82  ILVYSVTSIKSFEVIKVIHGKLLDMVGKV---QIPIMLVGNKKDLHMERVISYEEGKALA 138
           +LVY VT+  SF+ +     + L           P +++GNK DL   R +S    +   
Sbjct: 56  VLVYDVTAPNSFKNLDSWRDEFLIQASPRDPEHFPFVVLGNKVDLD-NRQVSTRRAQQWC 232

Query: 139 ESWNA-AFLESSAKE 152
           +S N   + E+SAKE
Sbjct: 233 QSKNDIPYYETSAKE 277
>00552
          Length = 455

 Score = 31.6 bits (70), Expect = 0.19,   Method: Compositional matrix adjust.
 Identities = 21/56 (37%), Positives = 32/56 (57%), Gaps = 1/56 (1%)
 Frame = -1

Query: 3   QSKSRKIAILGYRSVGKSSLTIQFVEGQFVDSYDPTIENTF-TKLITVNGQEYHLQ 57
           +S+  K+ +LG   VGKSSL  +FV  +F      TI   F TK + V+G+ + +Q
Sbjct: 455 KSRLLKVVLLGDGGVGKSSLMNRFVSNKFDAQSFHTIGVEFLTKDVVVDGETFTMQ 288

 Score = 27.7 bits (60), Expect = 2.6,   Method: Compositional matrix adjust.
 Identities = 13/51 (25%), Positives = 26/51 (50%)
 Frame = -3

Query: 46  LITVNGQEYHLQLVDTAGQDEYSIFPQTYSIDINGYILVYSVTSIKSFEVI 96
           L+  +   +H  + DTAGQ+ Y      +    +  +L +SV ++KS + +
Sbjct: 183 LVAASPDVWHHGIWDTAGQERYKSLRTPFYRGTDCCLLTFSVDNLKSLQSL 31
>11142
          Length = 610

 Score = 28.1 bits (61), Expect = 2.4,   Method: Compositional matrix adjust.
 Identities = 11/33 (33%), Positives = 20/33 (60%)
 Frame = -3

Query: 52  QEYHLQLVDTAGQDEYSIFPQTYSIDINGYILV 84
           Q YHL LV   GQ+  ++F + + + I  Y+++
Sbjct: 146 QSYHLTLVHVVGQEVVALFGRQHPVHIALYVVL 48
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|33598964|ref|NP_780469.1| myosin heavy chain 10,
non-muscle [Mus musculus]
         (1976 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

25944                                                                 134   3e-31
25922                                                                 107   4e-23
01074                                                                 100   8e-21
01284                                                                  89   2e-17
31878                                                                  63   3e-16
33963                                                                  54   4e-07
20566                                                                  45   4e-04
30605                                                                  35   0.39 
09545                                                                  34   0.48 
>25944
          Length = 417

 Score =  134 bits (337), Expect = 3e-31,   Method: Compositional matrix adjust.
 Identities = 71/127 (55%), Positives = 103/127 (81%)
 Frame = -3

Query: 1548 LEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLLKQVRELEAELED 1607
            +EELEDELQA ED KLRLEVNM A++ +++ ++  R+EQ EE KR LL+Q+RE+EAELED
Sbjct: 415  IEELEDELQAAEDGKLRLEVNMNALREKYKNEVAGREEQEEESKRSLLRQLREMEAELED 236

Query: 1608 ERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARAS 1667
            ERKQRALAV ++ K++ D++ +E Q+E A K +++ +KQ +K+ AQMKD+Q ELE+AR +
Sbjct: 235  ERKQRALAVNARNKLQGDVQGMEQQLEMATKVKEDAVKQYKKIFAQMKDFQHELEDARIA 56

Query: 1668 RDEIFAQ 1674
            R+++ AQ
Sbjct: 55   REDMAAQ 35
>25922
          Length = 422

 Score =  107 bits (268), Expect = 4e-23,   Method: Composition-based stats.
 Identities = 58/133 (43%), Positives = 80/133 (60%)
 Frame = -2

Query: 392 FTRAILTPRIKVGRDYVQKAQTKEQADFAVEALAKATYERLFRWLVHRINKALDRTKRQG 451
              A++   + V  D V    +  ++ +A +AL KA Y R+F WLVHRIN ++     Q 
Sbjct: 409 LAHALMHRTVAVKGDMVTTDLSVSESSYARDALCKALYSRMFSWLVHRINDSIKVRGAQR 230

Query: 452 ASFIGILDIAGFEIFELNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDF 511
              +G+LDI GFE+FE NSFEQ  INY NEKLQQ+F       EQEEY +EGIEW  +++
Sbjct: 229 TKVMGVLDIYGFEVFENNSFEQFIINYCNEKLQQIFIELTLKEEQEEYIKEGIEWIHVEY 50

Query: 512 GLDLQPCIDLIER 524
             +   C +LIE+
Sbjct: 49  FNNAVIC-ELIEK 14
>01074
          Length = 2584

 Score =  100 bits (248), Expect = 8e-21,   Method: Compositional matrix adjust.
 Identities = 63/150 (42%), Positives = 85/150 (56%)
 Frame = -2

Query: 1776 ERSAAQKSDNARQQLERQNKELKAKLQELEGAVKSKFKATISALEAKIGXXXXXXXXXXX 1835
            ERS +QK +N R  LERQNKE++ KLQELEG  +++ KATI     +             
Sbjct: 2583 ERSVSQKLENQRLALERQNKEMREKLQELEGQSRARTKATIGRTGGQDCQPGRTTGPGGQ 2404

Query: 1836 XXXXXNKLVRRTEKKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQLXXXXXXXTR 1895
                      +  +  + + +Q EDERR ADQYKEQ++K N R+K LKRQ+        R
Sbjct: 2403 GASSPGSHEPQDGQASQRLQIQAEDERRSADQYKEQLDKMNNRVKALKRQVDEAEEECAR 2224

Query: 1896 ANASRRKLQRELDDATEANEGLSREVSTLK 1925
             NA +RK+QRELDD  E N+ L RE  +L+
Sbjct: 2223 INAQKRKVQRELDDQMEQNDVLVRETQSLR 2134
>01284
          Length = 1603

 Score = 89.0 bits (219), Expect = 2e-17,   Method: Compositional matrix adjust.
 Identities = 45/136 (33%), Positives = 75/136 (55%), Gaps = 5/136 (3%)
 Frame = +2

Query: 650 FRTVGQLYKESLTKLMATLRNTNPNFVRCIIPNHEKRAGKLDPHL-----VLDQLRCNGV 704
           F +VG  +++ L  LM  L++T  NF+RCI PN      K+  HL     +L QL+C G+
Sbjct: 11  FISVGTKFRKQLLVLMDKLKSTGTNFIRCIKPN-----VKMVDHLFEGANILSQLQCAGM 175

Query: 705 LEGIRICRQGFPNRIVFQEFRQRYEILTPNAIPKGFMDGKQACERMIRALELDPNLYRIG 764
           +  + + +QGFP+R  F E    Y+   P  + +  +D +  C+ + +AL LD   ++ G
Sbjct: 176 VSVLELMQQGFPSRTPFSELYNMYKKYLPPELSR--LDPRLFCKSLFKALGLDDKDFKFG 349

Query: 765 QSKIFFRAGVLAHLEE 780
            +K+FFR G  A  ++
Sbjct: 350 LTKVFFRPGKFAEFDQ 397
>31878
          Length = 1178

 Score = 62.8 bits (151), Expect(2) = 3e-16,   Method: Compositional matrix adjust.
 Identities = 28/60 (46%), Positives = 40/60 (66%)
 Frame = -1

Query: 815  ALKVLQRNCAAYLKLRHWQWWRVFTKVKPLLQVTRQEEELQAKDEELLKVKEKQTKVEGE 874
            A++ +QRN   Y+K+R W WW+++TKVKP+L V R EEEL     +L  +K K  K+E E
Sbjct: 1055 AVRCIQRNVQKYMKIREWSWWKLYTKVKPILNVHRTEEELLEAQADLEAMKTKTEKLEKE 876

 Score = 42.4 bits (98), Expect(2) = 3e-16,   Method: Composition-based stats.
 Identities = 19/31 (61%), Positives = 23/31 (74%)
 Frame = -2

Query: 774  VLAHLEEERDLKITDIIIFFQAVCRGYLARK 804
            VL+ LE  RD K+T I+  FQA+CRGYL RK
Sbjct: 1177 VLSQLEAGRDEKLTGIVTQFQALCRGYLGRK 1085
>33963
          Length = 392

 Score = 54.3 bits (129), Expect = 4e-07,   Method: Compositional matrix adjust.
 Identities = 40/129 (31%), Positives = 59/129 (45%)
 Frame = +2

Query: 1418 LEKTKNRLQQELDDLTVDLDHQRQIVSNLEKKQKKFDQLLAEEKGISXXXXXXXXXXXXX 1477
            LEK K RLQ EL+DL VD++      +NLEKKQ+ FD+ +AE +                
Sbjct: 2    LEKAKARLQGELEDLMVDVERSNANANNLEKKQRAFDKTIAEWQAKVNDLQGELENAQKE 181

Query: 1478 XXXXXXXXXXXXXXXXXXXXXXXXXXRQNKQLRADMEDLMSSKDDVGKNVHELEKSKRAL 1537
                                      R+NK L  ++ DL     D G++VHE EK+++ L
Sbjct: 182  ARGYSAELFRVKAQLEEAVDSTEALRRENKNLADEIHDLTDQLSDGGRSVHESEKARKRL 361

Query: 1538 EQQVEEMRT 1546
            E + EE++ 
Sbjct: 362  ELEKEELQA 388

 Score = 32.0 bits (71), Expect = 2.6,   Method: Compositional matrix adjust.
 Identities = 29/124 (23%), Positives = 66/124 (53%)
 Frame = +2

Query: 1508 QLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEV 1567
            +L+ ++EDLM   +    N + LEK +RA ++ + E + ++ +L+ EL+  +        
Sbjct: 20   RLQGELEDLMVDVERSNANANNLEKKQRAFDKTIAEWQAKVNDLQGELENAQKEARGYSA 199

Query: 1568 NMQAMKAQFERDLQTRDEQNEEKKRLLLKQVRELEAELEDERKQRALAVASKKKMEIDLK 1627
             +  +KAQ E  + + +    E K  L  ++ +L  +L D  +    +  ++K++E++ +
Sbjct: 200  ELFRVKAQLEEAVDSTEALRRENKN-LADEIHDLTDQLSDGGRSVHESEKARKRLELEKE 376

Query: 1628 DLEA 1631
            +L+A
Sbjct: 377  ELQA 388
>20566
          Length = 911

 Score = 44.7 bits (104), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 40/156 (25%), Positives = 75/156 (48%)
 Frame = +3

Query: 1757 DRFRKTTLQVDTLNTELAAERSAAQKSDNARQQLERQNKELKAKLQELEGAVKSKFKATI 1816
            DR +K       L  EL  E+  + + +  R+ +E Q K+++ +L E E       K  I
Sbjct: 33   DRSKKAMADAARLADELRQEQEHSMQVEKLRKGMEGQIKDMQVRLDEAEAQALKGGKKII 212

Query: 1817 SALEAKIGXXXXXXXXXXXXXXXXNKLVRRTEKKLKEIFMQVEDERRHADQYKEQMEKAN 1876
              LE ++                  K +R+ +++LKE+  Q +++R++ ++ ++ ++K  
Sbjct: 213  QKLEQRVRELEMELDGEQRRHAETQKNMRKADRRLKELAFQSDEDRKNQERIQDLVDKLQ 392

Query: 1877 ARMKQLKRQLXXXXXXXTRANASRRKLQRELDDATE 1912
            A++K  KRQ+           A  RK+Q EL+DA E
Sbjct: 393  AKIKTYKRQVEEAEEIAAVNLAKFRKVQNELEDAEE 500

 Score = 38.1 bits (87), Expect = 0.035,   Method: Compositional matrix adjust.
 Identities = 38/122 (31%), Positives = 73/122 (59%), Gaps = 8/122 (6%)
 Frame = +3

Query: 1551 LEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEK-----KRLLLK---QVRELE 1602
            L DEL+  ++  +++E   + M+ Q  +D+Q R ++ E +     K+++ K   +VRELE
Sbjct: 69   LADELRQEQEHSMQVEKLRKGMEGQI-KDMQVRLDEAEAQALKGGKKIIQKLEQRVRELE 245

Query: 1603 AELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELE 1662
             EL+ E+++ A    + +K +  LK+L  Q +   K ++ +   + KLQA++K Y+R++E
Sbjct: 246  MELDGEQRRHAETQKNMRKADRRLKELAFQSDEDRKNQERIQDLVDKLQAKIKTYKRQVE 425

Query: 1663 EA 1664
            EA
Sbjct: 426  EA 431
>30605
          Length = 336

 Score = 34.7 bits (78), Expect = 0.39,   Method: Composition-based stats.
 Identities = 27/85 (31%), Positives = 46/85 (54%), Gaps = 5/85 (5%)
 Frame = -3

Query: 322 DKDNFQETMEAMHIMGFSHEEILSMLKVVSSVLQFGNISFKKERNTDQASM-----PENT 376
           D  +F+   EAM  MG S  + +++  +V++VL  GNI+F+ + +  +         E++
Sbjct: 328 DVRDFKVCDEAMTRMGVSDADKMAIFMLVAAVLHLGNIAFEDDHDDTKGGCKVLEEAEDS 149

Query: 377 VAQKLCHLLGMNVMEFTRAILTPRI 401
           +A     LLG++ ME  R  LT RI
Sbjct: 148 LATAAV-LLGVDKMEL-RDSLTSRI 80
>09545
          Length = 1614

 Score = 34.3 bits (77), Expect = 0.48,   Method: Compositional matrix adjust.
 Identities = 24/66 (36%), Positives = 35/66 (53%), Gaps = 3/66 (4%)
 Frame = -1

Query: 1877 ARMKQLKRQLXXXXXXXTRANASRRKLQRELDDATEANEGLSREVSTLKNRLRRGG---P 1933
             R+++LKR L            S R++QR  D+  E  + L+ +V  L+NRLRRG    P
Sbjct: 1449 GRVEELKRDLATAEDEVDMQTNSVRRMQRSNDELQEQVDDLTLQVDHLQNRLRRGSQSIP 1270

Query: 1934 ISFSSS 1939
             + SSS
Sbjct: 1269 KTRSSS 1252
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|225637533|ref|NP_795904.3| neuronal cell adhesion
molecule isoform 1 [Mus musculus]
         (1256 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

19544                                                                 133   4e-31
35419                                                                  50   1e-14
25455                                                                  75   2e-13
26757                                                                  66   1e-10
06028                                                                  65   2e-10
29990                                                                  63   9e-10
36498                                                                  40   1e-07
38127                                                                  56   1e-07
08294                                                                  50   4e-06
13135                                                                  49   9e-06
34369                                                                  47   5e-05
20110                                                                  45   8e-05
37675                                                                  46   1e-04
17679                                                                  45   2e-04
17229                                                                  44   3e-04
34811                                                                  33   8e-04
11855                                                                  43   0.001
36700                                                                  42   0.002
29932                                                                  40   0.007
18345                                                                  39   0.010
25766                                                                  39   0.012
07945                                                                  39   0.014
11788                                                                  38   0.020
32888                                                                  32   0.030
12764                                                                  38   0.033
05091                                                                  37   0.066
27666                                                                  36   0.11 
20244                                                                  28   0.19 
06033                                                                  35   0.21 
19356                                                                  35   0.27 
04057                                                                  33   0.50 
17530                                                                  33   0.50 
30103                                                                  33   0.82 
29881                                                                  33   0.92 
22543                                                                  32   1.8  
37263                                                                  32   2.1  
10921                                                                  31   2.6  
>19544
          Length = 1421

 Score =  133 bits (335), Expect = 4e-31,   Method: Compositional matrix adjust.
 Identities = 123/452 (27%), Positives = 193/452 (42%), Gaps = 55/452 (12%)
 Frame = +2

Query: 811  YLIKVQALNDVGFAPEPAAVMGHSGEDLPMVAPGNVRVSVVNSTLAEVHWDPVPPKSVRG 870
            Y ++V A+N  G  P       + GE  P   P NV+    +++  +V W   PP++  G
Sbjct: 20   YEVQVLAVNGKGRGPPSTPATIYVGEAAPTEGPSNVQAVNKSASSIQVTWVAPPPETQNG 199

Query: 871  HLQGYRIYYWKTQSSSKRNRRHIEKKILTFQGTKTHGMLPGLQPYSHYALNVRVVNGKGE 930
             L GY++ Y+K  SS++          LT    +TH +L  L+ ++ Y + V+  N  GE
Sbjct: 200  GLSGYKVLYYKQSSSAEEE--------LTRITAETHILLESLETFTVYFIAVQPYNLAGE 355

Query: 931  GPASTDRGFHTPEGVPSAPSSLKIVNPTLDSLTLEWDPPSHPNGILTEYILQYQPINSTH 990
            GP S      T EGVPSAP S++  N T+  L + +DPP+ PNG +  Y +QY P + + 
Sbjct: 356  GPRSALVSAQTSEGVPSAPQSIRFTNITMRQLMVHFDPPTTPNGHILLYEMQYFPKDESR 535

Query: 991  E--LGPLVDLKIPANKTRWTLKNLNFSTRYKFYFYAQTSVGPGSQITEEAI--TTVDEAG 1046
               L P   L+  AN+TR  +  L     YKF   A TS+G G  +  E    TT   +G
Sbjct: 536  YGFLAPKRILR--ANETRVVVTELEKRVWYKFIISANTSIGKGESLEAEIKNRTTTWVSG 709

Query: 1047 IP------------PPDV---GAGKGKEEW---RKEIVNGSR-------------SFFGL 1075
             P            P D+    AG  +  W   R +   GSR             +  G 
Sbjct: 710  CPRTAQC*SAVQIFPXDLERWRAGVHQHFWLLHRSQAKRGSRLPNNPARITSESKAEIGW 889

Query: 1076 KGLMPGTAYKVRVGAEGDSGF----VSSEDVFETGPAMASRQVDIATQGWFIGL--MCAV 1129
              L P T Y+ RV A  D G     + SE V     A+  +     T+ WF+ +  +  +
Sbjct: 890  SSLNPNTGYQFRVMAINDDGISDESLPSERVVTPSFAIVQKAKPFHTEWWFLVIIALTGI 1069

Query: 1130 AXXXXXXXXVCFIRRNKGGKYPVKEKEDAH---ADPEIQPMKEDDGTFGEYSDAEDHKPL 1186
                     +C + R K     +K  + A+   ++P + P + ++G F  Y   +  + +
Sbjct: 1070 IVILVIISVLCLLTRRKKTGEEMKRSQTANTVLSEPSV-PSEPEEGGFPTYEMRQSRRNM 1246

Query: 1187 -----------KKGSRTPSDRTVKKEDSDDSL 1207
                        +    PS  +V   D DD++
Sbjct: 1247 APRTGSIKNIYARAPPRPSPASVAYSDDDDAM 1342

 Score = 63.9 bits (154), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 47/171 (27%), Positives = 76/171 (44%)
 Frame = +2

Query: 710 NYSFRVMAENSIGRSMPSEASEQYLTKAAEPDQNPMAVEGLGTEPDNLVITWKPLNGFQS 769
            Y  +V+A N  GR  PS  +  Y+ +AA P + P  V+ +     ++ +TW        
Sbjct: 17  TYEVQVLAVNGKGRGPPSTPATIYVGEAA-PTEGPSNVQAVNKSASSIQVTWVAPPPETQ 193

Query: 770 NGPGLQYKVSWRQKDGDDEWTSVVVANVSKYIVSGTPTFVPYLIKVQALNDVGFAPEPAA 829
           NG    YKV + ++    E     +   +  ++    TF  Y I VQ  N  G  P  A 
Sbjct: 194 NGGLSGYKVLYYKQSSSAEEELTRITAETHILLESLETFTVYFIAVQPYNLAGEGPRSAL 373

Query: 830 VMGHSGEDLPMVAPGNVRVSVVNSTLAEVHWDPVPPKSVRGHLQGYRIYYW 880
           V   + E +P  AP ++R + +      VH+D  PP +  GH+  Y + Y+
Sbjct: 374 VSAQTSEGVPS-APQSIRFTNITMRQLMVHFD--PPTTPNGHILLYEMQYF 517
>35419
          Length = 623

 Score = 49.7 bits (117), Expect(2) = 1e-14,   Method: Compositional matrix adjust.
 Identities = 40/144 (27%), Positives = 64/144 (44%), Gaps = 7/144 (4%)
 Frame = -2

Query: 534 LEIKDPTRIIKQPEYAVVQRGSKVSFECRVKHD----HTLIPTIMWLKDNGELPN-DERF 588
           L ++  T+I + P    V  G+   F C    D    H L   I W+KDN E+   ++R 
Sbjct: 592 LLVRRKTQIEQAPMDLEVNAGTDAKFTCSGTTDPEEVHML--KIKWMKDNKEISTVEQRM 419

Query: 589 STD--KDHLVVSDVKDDDGGTYTCTANTTLDXXXXXXVLRVVAPTPTPAPIYDVPNPPFD 646
           +T+   + L +S     D GTYTC +   LD      +L V           D P+   +
Sbjct: 418 TTNIQDNSLTISGTIVRDSGTYTCISTNGLDSAEASAMLTV----------KDRPDVASE 269

Query: 647 LELTNQLDKSVQLTWTPGDDNNSP 670
           +++  + D +  + W PG  NN+P
Sbjct: 268 VKI-EKCDDNATILWMPGSYNNAP 200

 Score = 49.7 bits (117), Expect(2) = 1e-14,   Method: Compositional matrix adjust.
 Identities = 23/58 (39%), Positives = 35/58 (60%)
 Frame = -1

Query: 670 PITKFIIEYEDAMHDAGLWRHQAEVSGTQTTAQLKLSPYVNYSFRVMAENSIGRSMPS 727
           P+  ++I+Y  +  +   W    +V    T+A + LSP+VNY+FRV+A N IG S PS
Sbjct: 203 PVQYYVIQYNTSF-NPDTWTFAVQVDSIFTSANVSLSPWVNYTFRVIAYNKIGESDPS 33

 Score = 32.0 bits (71), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 34/123 (27%), Positives = 52/123 (42%), Gaps = 5/123 (4%)
 Frame = -2

Query: 459 QVIANRPALLDCAFFGSP----MPTIEWFKGTKG-SALHEDIYVLHDNGTLEIPVAQKDS 513
           +V A   A   C+    P    M  I+W K  K  S + + +     + +L I       
Sbjct: 544 EVNAGTDAKFTCSGTTDPEEVHMLKIKWMKDNKEISTVEQRMTTNIQDNSLTISGTIVRD 365

Query: 514 TGTYTCVARNKLGMAKNEVHLEIKDPTRIIKQPEYAVVQRGSKVSFECRVKHDHTLIPTI 573
           +GTYTC++ N L  A+    L +KD      +P+ A     S+V  E   K D     TI
Sbjct: 364 SGTYTCISTNGLDSAEASAMLTVKD------RPDVA-----SEVKIE---KCDDN--ATI 233

Query: 574 MWL 576
           +W+
Sbjct: 232 LWM 224

 Score = 30.0 bits (66), Expect = 5.6,   Method: Compositional matrix adjust.
 Identities = 19/92 (20%), Positives = 36/92 (39%), Gaps = 4/92 (4%)
 Frame = -2

Query: 360 APQNLVLSPGENGTLICRANGNPKP----RISWLTNGVPIEIALDDPSRKIDGDTIIFSN 415
           AP +L ++ G +    C    +P+     +I W+ +   I       +  I  +++  S 
Sbjct: 559 APMDLEVNAGTDAKFTCSGTTDPEEVHMLKIKWMKDNKEISTVEQRMTTNIQDNSLTISG 380

Query: 416 VQESSSAVYQCNASNKYGYLLANAFVNVLAEP 447
                S  Y C ++N      A+A + V   P
Sbjct: 379 TIVRDSGTYTCISTNGLDSAEASAMLTVKDRP 284
>25455
          Length = 444

 Score = 74.7 bits (182), Expect = 2e-13,   Method: Compositional matrix adjust.
 Identities = 42/125 (33%), Positives = 60/125 (48%), Gaps = 12/125 (9%)
 Frame = +1

Query: 332 YQCIAKNALGAVHHT------ISVTVKAAPYWIVAPQNLVLSPGENGTLICRANGNPKPR 385
           Y+C A+     VHH       + V V++AP W+VAPQ   +  GE   + C A   P P 
Sbjct: 1   YRCWAE---STVHHINFPLREMRVVVQSAPSWVVAPQVTEVEVGETAEITCNATAIPDPV 171

Query: 386 ISWLTNGVPIEIALDDPSR------KIDGDTIIFSNVQESSSAVYQCNASNKYGYLLANA 439
            +W  NG  I   ++   R       +  D +I  NV      V QCN +N+YG+L A+ 
Sbjct: 172 TNWFVNGREISDVVEHDVRFQSGRFDLTSDRLILRNVTIEGRMVVQCNVTNRYGHLWADV 351

Query: 440 FVNVL 444
            +NVL
Sbjct: 352 SLNVL 366
>26757
          Length = 392

 Score = 65.9 bits (159), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 45/131 (34%), Positives = 65/131 (49%)
 Frame = -2

Query: 1098 SSEDVFETGPAMASRQVDIATQGWFIGLMCAVAXXXXXXXXVCFIRRNKGGKYPVKEKED 1157
            SS+  F T  ++ +++  + + GWFIG+M A+A        VC ++RN+G +Y       
Sbjct: 388  SSKRRFNTA-SIGAKKGSVLSAGWFIGMMVAIAILLLILIIVCIVKRNRGKEYKFP---- 224

Query: 1158 AHADPEIQPMKEDDGTFGEYSDAEDHKPLKKGSRTPSDRTVKKEDSDDSLVDYGEGVNGQ 1217
                PE     E  G F E + +E +      S       V  ED  DSL +YG+    +
Sbjct: 223  ----PEKDTTDETPGHFNEMAKSEKNGLNTSASFERDPEKVPLEDETDSLEEYGDVDPAK 56

Query: 1218 FNEDGSFIGQY 1228
            FNEDGSFIGQY
Sbjct: 55   FNEDGSFIGQY 23
>06028
          Length = 1358

 Score = 65.1 bits (157), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 63/245 (25%), Positives = 95/245 (38%), Gaps = 29/245 (11%)
 Frame = +1

Query: 326 EADSGNYQCIAKN--ALGAVHHTISVT-------VKAAPYWIVAPQN-LVLSPGENGTLI 375
           E DSG Y C+A N  A   + H +           K A ++   P     L+P  N T +
Sbjct: 106 EKDSGVYFCVASNEGAQNKISHQVDFKGRERFTLEKTAGFFHRDPNKPHFLNPLGNQT-V 282

Query: 376 CRANGNPKPRISWLTNGVPIEIALDDPSRKIDGD-----------TIIFSNVQESSSAVY 424
           C   G       ++ +  PIE+      R +DG            T+   N  E     Y
Sbjct: 283 CHG-GTVAISAEFMQSSTPIEVKWLRNRRPVDGPSVQTFNERGIYTLAIMNAGEEHEGTY 459

Query: 425 QCNASNKYGYLLANAFVNVLA------EPPRILTSANTLYQVIANRPALLDCAFFGSPMP 478
            C ASN +G + ++  ++V         PP  L+   T  ++    P  L     G P P
Sbjct: 460 TCLASNAFGRIESHVNIDVAVGVEKEVRPPLFLSRPETEMKIAVGDPFSLSFRIAGDPKP 639

Query: 479 TIEWFKGTKGSALHEDIY--VLHDNGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEI 536
            + + KGTK     + +   V  D     +  +Q   +GTY  VARN  G  +  V + I
Sbjct: 640 RLVFMKGTKDITQSDRVSKEVSDDYTRFTVQKSQISDSGTYFVVARNDFGTDRIFVTITI 819

Query: 537 KDPTR 541
           K P +
Sbjct: 820 KTPKK 834

 Score = 57.8 bits (138), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 53/203 (26%), Positives = 90/203 (44%), Gaps = 15/203 (7%)
 Frame = +1

Query: 262 PTFLTPEGNESHKEELRGNVLSLECIAEGLPTPI-IYWIKE----DGMLPANRTFYRNFK 316
           P FL P GN++      G  +++        TPI + W++     DG  P+ +TF     
Sbjct: 247 PHFLNPLGNQT---VCHGGTVAISAEFMQSSTPIEVKWLRNRRPVDG--PSVQTFNERGI 411

Query: 317 KTLQITHVSEADSGNYQCIAKNALGAVHHTISVTVKAA-------PYWIVAPQN-LVLSP 368
            TL I +  E   G Y C+A NA G +   +++ V          P ++  P+  + ++ 
Sbjct: 412 YTLAIMNAGEEHEGTYTCLASNAFGRIESHVNIDVAVGVEKEVRPPLFLSRPETEMKIAV 591

Query: 369 GENGTLICRANGNPKPRISWLTNGVPIEIALDDPSRKIDGDTIIFS--NVQESSSAVYQC 426
           G+  +L  R  G+PKPR+ ++     I  + D  S+++  D   F+    Q S S  Y  
Sbjct: 592 GDPFSLSFRIAGDPKPRLVFMKGTKDITQS-DRVSKEVSDDYTRFTVQKSQISDSGTYFV 768

Query: 427 NASNKYGYLLANAFVNVLAEPPR 449
            A N +G      FV +  + P+
Sbjct: 769 VARNDFG--TDRIFVTITIKTPK 831

 Score = 44.7 bits (104), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 57/262 (21%), Positives = 99/262 (37%), Gaps = 35/262 (13%)
 Frame = +1

Query: 386 ISWLTNGVPIEIALDDPSRKIDG----DTIIFSNVQESSSAVYQCNASNKYGYLLANAFV 441
           I W+    PI  + D+  +++D       +I  N  E  S VY C ASN+      +  V
Sbjct: 4   IQWMKGTEPI--SNDEKYQQVDQADGYSKLIIHNPVEKDSGVYFCVASNEGAQNKISHQV 177

Query: 442 NVLAEPPRILTSANTLYQVIANRPALLD----------------CAFFGSPMPT-IEWFK 484
           +        L      +    N+P  L+                  F  S  P  ++W +
Sbjct: 178 DFKGRERFTLEKTAGFFHRDPNKPHFLNPLGNQTVCHGGTVAISAEFMQSSTPIEVKWLR 357

Query: 485 GTKGSALHEDIYVLHDNG--TLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIK----- 537
             +       +   ++ G  TL I  A ++  GTYTC+A N  G  ++ V++++      
Sbjct: 358 NRR-PVDGPSVQTFNERGIYTLAIMNAGEEHEGTYTCLASNAFGRIESHVNIDVAVGVEK 534

Query: 538 --DPTRIIKQPEYAV-VQRGSKVSFECRVKHDHTLIPTIMWLKDNGELPNDERFST---- 590
              P   + +PE  + +  G   S   R+  D    P ++++K   ++   +R S     
Sbjct: 535 EVRPPLFLSRPETEMKIAVGDPFSLSFRIAGDPK--PRLVFMKGTKDITQSDRVSKEVSD 708

Query: 591 DKDHLVVSDVKDDDGGTYTCTA 612
           D     V   +  D GTY   A
Sbjct: 709 DYTRFTVQKSQISDSGTYFVVA 774

 Score = 32.3 bits (72), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 37/133 (27%), Positives = 53/133 (39%), Gaps = 6/133 (4%)
 Frame = +1

Query: 69  PPSFSWTRNGTHFDIDKDPLVTMKPGSGTLVINIMSEGKAETYEGVYQCTARNERGAAVS 128
           P    W RN    D    P V      G   + IM+ G  E +EG Y C A N  G   S
Sbjct: 334 PIEVKWLRNRRPVD---GPSVQTFNERGIYTLAIMNAG--EEHEGTYTCLASNAFGRIES 498

Query: 129 N-NI-----VVRPSRSPLWTKERLEPIVLQNGQSLVLPCRPPIGLPPAIIFWMDNSFQRL 182
           + NI     V +  R PL+       + +  G    L  R      P ++F      + +
Sbjct: 499 HVNIDVAVGVEKEVRPPLFLSRPETEMKIAVGDPFSLSFRIAGDPKPRLVFMKGT--KDI 672

Query: 183 PQSERVSQGLNGD 195
            QS+RVS+ ++ D
Sbjct: 673 TQSDRVSKEVSDD 711
>29990
          Length = 434

 Score = 62.8 bits (151), Expect = 9e-10,   Method: Compositional matrix adjust.
 Identities = 34/109 (31%), Positives = 54/109 (49%), Gaps = 6/109 (5%)
 Frame = +3

Query: 289 EGLPTPIIYWIKEDGM--LPANRTFYRNFKKTLQITHVSEADSGNYQCIAKNALGAVH-H 345
           EG P P I W+  +    +  +  F      TL I    + D G Y+CIA+N  G  H +
Sbjct: 3   EGKPVPEIVWMHNNNRVEISGDSRFSLLHDGTLMIEDAQDDDRGVYECIARNVAGETHSN 182

Query: 346 TISVTV---KAAPYWIVAPQNLVLSPGENGTLICRANGNPKPRISWLTN 391
            + +     + AP +   PQ++V   G+   L+C+A+G+P+P  SW  N
Sbjct: 183 QVELRYFGERVAPXFTQRPQDIVTVEGQTVQLVCQASGHPRPTFSWTRN 329

 Score = 47.8 bits (112), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 37/116 (31%), Positives = 53/116 (45%), Gaps = 3/116 (2%)
 Frame = +3

Query: 65  KGKPPPSFSWTRNGTHFDIDKDPLVTMKPGSGTLVINIMSEGKAETYEGVYQCTARNERG 124
           +GKP P   W  N    +I  D   ++    GTL+I    E   +   GVY+C ARN  G
Sbjct: 3   EGKPVPEIVWMHNNNRVEISGDSRFSLLH-DGTLMI----EDAQDDDRGVYECIARNVAG 167

Query: 125 AAVSNNIVVR---PSRSPLWTKERLEPIVLQNGQSLVLPCRPPIGLPPAIIFWMDN 177
              SN + +R      +P +T +R + IV   GQ++ L C+   G P     W  N
Sbjct: 168 ETHSNQVELRYFGERVAPXFT-QRPQDIVTVEGQTVQLVCQAS-GHPRPTFSWTRN 329

 Score = 44.3 bits (103), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 35/115 (30%), Positives = 48/115 (41%), Gaps = 6/115 (5%)
 Frame = +3

Query: 474 GSPMPTIEWFKGTKGSALHED--IYVLHDNGTLEIPVAQKDSTGTYTCVARNKLG-MAKN 530
           G P+P I W        +  D    +LHD GTL I  AQ D  G Y C+ARN  G    N
Sbjct: 6   GKPVPEIVWMHNNNRVEISGDSRFSLLHD-GTLMIEDAQDDDRGVYECIARNVAGETHSN 182

Query: 531 EVHLEI---KDPTRIIKQPEYAVVQRGSKVSFECRVKHDHTLIPTIMWLKDNGEL 582
           +V L     +      ++P+  V   G  V   C+        PT  W ++  +L
Sbjct: 183 QVELRYFGERVAPXFTQRPQDIVTVEGQTVQLVCQASGHPR--PTFSWTRNLEQL 341

 Score = 42.4 bits (98), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 33/124 (26%), Positives = 49/124 (39%), Gaps = 12/124 (9%)
 Frame = +3

Query: 380 GNPKPRISWLTNGVPIEIALDDPSRKIDGDTIIFSNVQESSSAVYQCNASNKYGYLLANA 439
           G P P I W+ N   +EI+ D     +   T++  + Q+    VY+C A N  G   +N 
Sbjct: 6   GKPVPEIVWMHNNNRVEISGDSRFSLLHDGTLMIEDAQDDDRGVYECIARNVAGETHSNQ 185

Query: 440 -----FVNVLA-----EPPRILTSANTLYQVIANRPALLDCAFFGSPMPTIEWFKGTK-- 487
                F   +A      P  I+T      Q++        C   G P PT  W +  +  
Sbjct: 186 VELRYFGERVAPXFTQRPQDIVTVEGQTVQLV--------CQASGHPRPTFSWTRNLEQL 341

Query: 488 GSAL 491
           GS L
Sbjct: 342 GSTL 353

 Score = 39.7 bits (91), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 19/46 (41%), Positives = 27/46 (58%), Gaps = 3/46 (6%)
 Frame = +3

Query: 570 IPTIMWLKDNG--ELPNDERFSTDKD-HLVVSDVKDDDGGTYTCTA 612
           +P I+W+ +N   E+  D RFS   D  L++ D +DDD G Y C A
Sbjct: 15  VPEIVWMHNNNRVEISGDSRFSLLHDGTLMIEDAQDDDRGVYECIA 152

 Score = 37.7 bits (86), Expect = 0.026,   Method: Compositional matrix adjust.
 Identities = 16/38 (42%), Positives = 24/38 (63%)
 Frame = +3

Query: 40  PTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRN 77
           P  TQ+ P+D +    + + + C+A G P P+FSWTRN
Sbjct: 219 PXFTQR-PQDIVTVEGQTVQLVCQASGHPRPTFSWTRN 329
>36498
          Length = 478

 Score = 40.0 bits (92), Expect(2) = 1e-07,   Method: Composition-based stats.
 Identities = 25/74 (33%), Positives = 34/74 (45%), Gaps = 4/74 (5%)
 Frame = +3

Query: 319 LQITHVSEADSGNYQCIAKNALGAVHHTISVTVK----AAPYWIVAPQNLVLSPGENGTL 374
           L+   VSE D+G Y C+A+N  G     + +TV     A    I  P   +L  G++  L
Sbjct: 231 LRFDPVSEGDAGRYVCVARNERGITEENVDLTVTRTGVAPQVNIDGPGRQMLVDGQSVEL 410

Query: 375 ICRANGNPKPRISW 388
            C A G   P I W
Sbjct: 411 SCSARGLRNPLIRW 452

 Score = 35.4 bits (80), Expect(2) = 1e-07,   Method: Composition-based stats.
 Identities = 16/43 (37%), Positives = 25/43 (58%)
 Frame = +1

Query: 261 PPTFLTPEGNESHKEELRGNVLSLECIAEGLPTPIIYWIKEDG 303
           PPT     G  +    L G+ + +EC+AEG PTP ++W + +G
Sbjct: 49  PPTVTVTPG--TRITALVGDRVDIECVAEGDPTPTVFWRRIEG 171

 Score = 34.3 bits (77), Expect(2) = 0.001,   Method: Composition-based stats.
 Identities = 30/84 (35%), Positives = 39/84 (46%), Gaps = 2/84 (2%)
 Frame = +3

Query: 93  PGSGTLVINIMSEGKAETYEGVYQCTARNERGAAVSNN--IVVRPSRSPLWTKERLEPIV 150
           PG+  L  + +SEG A    G Y C ARNERG    N    V R   +P    +     +
Sbjct: 216 PGTAGLRFDPVSEGDA----GRYVCVARNERGITEENVDLTVTRTGVAPQVNIDGPGRQM 383

Query: 151 LQNGQSLVLPCRPPIGLPPAIIFW 174
           L +GQS+ L C    GL   +I W
Sbjct: 384 LVDGQSVELSCSAR-GLRNPLIRW 452

 Score = 26.9 bits (58), Expect(2) = 0.001,   Method: Composition-based stats.
 Identities = 14/47 (29%), Positives = 21/47 (44%)
 Frame = +1

Query: 30 LDVPLDLVQPPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTR 76
          L   L +  PPT+T            + + I+C A+G P P+  W R
Sbjct: 22 LTASLVIQGPPTVTVTPGTRITALVGDRVDIECVAEGDPTPTVFWRR 162

 Score = 32.7 bits (73), Expect(2) = 0.003,   Method: Composition-based stats.
 Identities = 23/78 (29%), Positives = 34/78 (43%), Gaps = 4/78 (5%)
 Frame = +3

Query: 507 PVAQKDSTGTYTCVARNKLGMAKNEVHLEIKD----PTRIIKQPEYAVVQRGSKVSFECR 562
           PV++ D+ G Y CVARN+ G+ +  V L +      P   I  P   ++  G  V   C 
Sbjct: 243 PVSEGDA-GRYVCVARNERGITEENVDLTVTRTGVAPQVNIDGPGRQMLVDGQSVELSCS 419

Query: 563 VKHDHTLIPTIMWLKDNG 580
            +      P I W +  G
Sbjct: 420 ARGLRN--PLIRWRRPTG 467

 Score = 27.3 bits (59), Expect(2) = 0.003,   Method: Composition-based stats.
 Identities = 14/49 (28%), Positives = 23/49 (46%)
 Frame = +1

Query: 443 VLAEPPRILTSANTLYQVIANRPALLDCAFFGSPMPTIEWFKGTKGSAL 491
           V+  PP +  +  T    +      ++C   G P PT+ W +  +GSAL
Sbjct: 37  VIQGPPTVTVTPGTRITALVGDRVDIECVAEGDPTPTVFW-RRIEGSAL 180
>38127
          Length = 860

 Score = 55.8 bits (133), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 42/136 (30%), Positives = 65/136 (47%), Gaps = 16/136 (11%)
 Frame = -1

Query: 496 YVLHDNGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEI---KDPTRIIKQPEYAVVQ 552
           Y+ H+NGTLEI   +++  G YTCVA  +    K+ + +++     P  +       +VQ
Sbjct: 821 YIQHNNGTLEIQHPRRNFAGMYTCVAEYEEAGVKSSISVDVPFYAHPKVLPFDKSKNLVQ 642

Query: 553 RGSKVSFECRVKHDHTLIPTIMWLKDNGELPN--DERF-----------STDKDHLVVSD 599
             S V  EC+V       P + W  DN E+ +  D R+           S +   LV+ +
Sbjct: 641 DESLV-IECKVLGYPK--PVVSWYMDNVEIVDGADSRYSLKPANSYDGASIEGAKLVIEE 471

Query: 600 VKDDDGGTYTCTANTT 615
           V+ DD G YTC +N T
Sbjct: 470 VQFDDAGEYTCMSNYT 423

 Score = 44.3 bits (103), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 43/150 (28%), Positives = 65/150 (43%), Gaps = 16/150 (10%)
 Frame = -1

Query: 299 IKEDGMLPANRTFYRNFKKTLQITHVSEADSGNYQCIAKNALGAVHHTISVTVKAAPYWI 358
           IK DG       + ++   TL+I H     +G Y C+A+     V  +ISV V    +  
Sbjct: 845 IKVDG----KERYIQHNNGTLEIQHPRRNFAGMYTCVAEYEEAGVKSSISVDVPFYAHPK 678

Query: 359 VAP----QNLVLSPGENGTLICRANGNPKPRISWLTNGVPIEIALDD-----PSRKIDGD 409
           V P    +NLV    E+  + C+  G PKP +SW  + V I    D      P+   DG 
Sbjct: 677 VLPFDKSKNLV--QDESLVIECKVLGYPKPVVSWYMDNVEIVDGADSRYSLKPANSYDGA 504

Query: 410 TI-----IFSNVQESSSAVYQC--NASNKY 432
           +I     +   VQ   +  Y C  N ++K+
Sbjct: 503 SIEGAKLVIEEVQFDDAGEYTCMSNYTDKW 414

 Score = 31.2 bits (69), Expect = 2.9,   Method: Compositional matrix adjust.
 Identities = 18/68 (26%), Positives = 31/68 (45%)
 Frame = -1

Query: 29  ALDVPLDLVQPPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPL 88
           ++DVP     P  +     K+ + D  E++VI+C+  G P P  SW  +        D  
Sbjct: 710 SVDVPF-YAHPKVLPFDKSKNLVQD--ESLVIECKVLGYPKPVVSWYMDNVEIVDGADSR 540

Query: 89  VTMKPGSG 96
            ++KP + 
Sbjct: 539 YSLKPANS 516
>08294
          Length = 1849

 Score = 50.4 bits (119), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 32/104 (30%), Positives = 51/104 (49%), Gaps = 1/104 (0%)
 Frame = +2

Query: 424 YQCNASN-KYGYLLANAFVNVLAEPPRILTSANTLYQVIANRPALLDCAFFGSPMPTIEW 482
           Y C A++ + G + A   ++++ E P I   +N +  V     A+L C   GSP P I W
Sbjct: 5   YTCVATHPRQGVINATIHISIV-EWPAITVKSNNI-TVFEGHSAILHCVAKGSPSPDIAW 178

Query: 483 FKGTKGSALHEDIYVLHDNGTLEIPVAQKDSTGTYTCVARNKLG 526
           ++ ++    +   Y L  NGT++I     +  G Y CVA N  G
Sbjct: 179 YRDSQPILPNARRYTLFKNGTMKIRQVFMEDNGMYACVANNTAG 310

 Score = 45.1 bits (105), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 25/77 (32%), Positives = 39/77 (50%), Gaps = 1/77 (1%)
 Frame = +2

Query: 277 LRGNVLSLECIAEGLPTPIIYWIKEDGMLPANRTFYRNFKK-TLQITHVSEADSGNYQCI 335
             G+   L C+A+G P+P I W ++   +  N   Y  FK  T++I  V   D+G Y C+
Sbjct: 113 FEGHSAILHCVAKGSPSPDIAWYRDSQPILPNARRYTLFKNGTMKIRQVFMEDNGMYACV 292

Query: 336 AKNALGAVHHTISVTVK 352
           A N  G +  T S  ++
Sbjct: 293 ANNTAGPLAGTSSFALR 343

 Score = 41.6 bits (96), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 30/108 (27%), Positives = 49/108 (45%), Gaps = 3/108 (2%)
 Frame = +2

Query: 331 NYQCIAKNAL-GAVHHTISVTVKAAPYWIVAPQNLVLSPGENGTLICRANGNPKPRISWL 389
           +Y C+A +   G ++ TI +++   P   V   N+ +  G +  L C A G+P P I+W 
Sbjct: 2   DYTCVATHPRQGVINATIHISIVEWPAITVKSNNITVFEGHSAILHCVAKGSPSPDIAWY 181

Query: 390 TNGVPIEIALDDPSRK--IDGDTIIFSNVQESSSAVYQCNASNKYGYL 435
            +  PI   L +  R       T+    V    + +Y C A+N  G L
Sbjct: 182 RDSQPI---LPNARRYTLFKNGTMKIRQVFMEDNGMYACVANNTAGPL 316

 Score = 33.9 bits (76), Expect = 0.40,   Method: Compositional matrix adjust.
 Identities = 23/93 (24%), Positives = 38/93 (40%)
 Frame = +2

Query: 32  VPLDLVQPPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTM 91
           + + +V+ P IT +S    + +    I + C AKG P P  +W R+      +       
Sbjct: 53  IHISIVEWPAITVKSNNITVFEGHSAI-LHCVAKGSPSPDIAWYRDSQPILPNARRYTLF 229

Query: 92  KPGSGTLVINIMSEGKAETYEGVYQCTARNERG 124
           K G+  +    M +       G+Y C A N  G
Sbjct: 230 KNGTMKIRQVFMED------NGMYACVANNTAG 310
>13135
          Length = 849

 Score = 49.3 bits (116), Expect = 9e-06,   Method: Compositional matrix adjust.
 Identities = 35/114 (30%), Positives = 52/114 (45%), Gaps = 4/114 (3%)
 Frame = -1

Query: 279 GNVLSLECIAEGLPTPIIYWIKEDG-MLPANRTFYRNFKKTLQITHVSEADSGNYQCIAK 337
           G  L L C A G PTP + W +  G +LP+      + +  L I  +    +G Y+C + 
Sbjct: 336 GQSLVLRCHASGRPTPSVKWTRMAGELLPSGG--REHLESDLVIPQLKPEHAGIYKCSSS 163

Query: 338 NALGAVHHTISVTVKAAPYWIVAPQNLVLSPGENGTLICRANGNPKPR---ISW 388
           N+ G+    I VTV  AP    A   +  + G    L+C   G P P+   I+W
Sbjct: 162 NSAGSDFRNIRVTVNFAPVLSSANTVVQQAQGYVKELVCVVKGYPTPKADDITW 1

 Score = 43.5 bits (101), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 55/234 (23%), Positives = 91/234 (38%), Gaps = 30/234 (12%)
 Frame = -1

Query: 275 EELRGNVLS-------LECIAEGLPTPI-IYWIKEDGMLPANRTF--------YRNFKKT 318
           +E+ GN++S       L C+ E  P    + W+         RT         Y  FK +
Sbjct: 705 DEVEGNIISEINKDVQLXCVVENKPIDKEVQWVGTVVRNGTTRTIPVSIATRSYDPFKYS 526

Query: 319 ----------LQITHVSEADSGNYQCIAK----NALGAVHHTISVTVKAAPYWIVAPQNL 364
                     L+I +    D G Y C  +    N   A H  + + +      +    ++
Sbjct: 525 IDLPSPTSWRLRIQNGQVTDEGVYTCQVQLSNQNYAKAFHQLVIIQMPQISD-LDTSSDV 349

Query: 365 VLSPGENGTLICRANGNPKPRISWLTNGVPIEIALDDPSRKIDGDTIIFSNVQESSSAVY 424
             S G++  L C A+G P P + W    +  E+        ++ D +I   ++   + +Y
Sbjct: 348 SKSEGQSLVLRCHASGRPTPSVKW--TRMAGELLPSGGREHLESDLVI-PQLKPEHAGIY 178

Query: 425 QCNASNKYGYLLANAFVNVLAEPPRILTSANTLYQVIANRPALLDCAFFGSPMP 478
           +C++SN  G    N  V V   P  +L+SANT+ Q        L C   G P P
Sbjct: 177 KCSSSNSAGSDFRNIRVTVNFAP--VLSSANTVVQQAQGYVKELVCVVKGYPTP 22

 Score = 35.4 bits (80), Expect = 0.14,   Method: Compositional matrix adjust.
 Identities = 25/105 (23%), Positives = 47/105 (44%), Gaps = 9/105 (8%)
 Frame = -1

Query: 34  LDLVQPPTITQ-QSPKDYIIDPRENIVIQCEAKGKPPPSFSWTR-------NGTHFDIDK 85
           L ++Q P I+   +  D      +++V++C A G+P PS  WTR       +G    ++ 
Sbjct: 402 LVIIQMPQISDLDTSSDVSKSEGQSLVLRCHASGRPTPSVKWTRMAGELLPSGGREHLES 223

Query: 86  DPLV-TMKPGSGTLVINIMSEGKAETYEGVYQCTARNERGAAVSN 129
           D ++  +KP                 + G+Y+C++ N  G+   N
Sbjct: 222 DLVIPQLKP----------------EHAGIYKCSSSNSAGSDFRN 136
>34369
          Length = 300

 Score = 47.0 bits (110), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 29/83 (34%), Positives = 44/83 (53%), Gaps = 1/83 (1%)
 Frame = +3

Query: 655 KSVQLTWTPG-DDNNSPITKFIIEYEDAMHDAGLWRHQAEVSGTQTTAQLKLSPYVNYSF 713
           + V + WT   DDNNSPIT + ++  +  +D  +       S  Q T    L+PY  Y+ 
Sbjct: 24  REVTVYWTTSRDDNNSPITSYTVQVNECENDTTVRELVTGGSTFQITIP-NLTPYTCYAI 200

Query: 714 RVMAENSIGRSMPSEASEQYLTK 736
           +V+A+NS+G S P   S+Q   K
Sbjct: 201 QVLAQNSVGFSDPGPQSDQVYYK 269
>20110
          Length = 820

 Score = 45.1 bits (105), Expect(2) = 8e-05,   Method: Compositional matrix adjust.
 Identities = 28/81 (34%), Positives = 41/81 (50%), Gaps = 2/81 (2%)
 Frame = -1

Query: 278 RGNVLSLECIAEGLPTPIIYWIKED-GMLPANRTFYRNFKKTLQITHVSEADSGNYQCIA 336
           +G   +L C A G+P P I W + D G LP     +R+   TL + +V+  D G Y+C+A
Sbjct: 508 QGQNSTLVCAASGIPAPNITWTRSDGGFLPIGVAQFRS--ATLPMNNVTVRDMGVYRCVA 335

Query: 337 KNALG-AVHHTISVTVKAAPY 356
            N +     H   V V  AP+
Sbjct: 334 DNNIKPPAEHLAEVLVFHAPF 272

 Score = 20.4 bits (41), Expect(2) = 8e-05,   Method: Compositional matrix adjust.
 Identities = 6/15 (40%), Positives = 10/15 (66%)
 Frame = -3

Query: 374 LICRANGNPKPRISW 388
           L C   G+P+P ++W
Sbjct: 215 LECIVKGHPEPTVTW 171

 Score = 40.8 bits (94), Expect(2) = 3e-04,   Method: Compositional matrix adjust.
 Identities = 35/125 (28%), Positives = 58/125 (46%), Gaps = 13/125 (10%)
 Frame = -1

Query: 319 LQITHVSEADSGNYQCIAKNALGAVHH------TISVTVKAAPYWIVAPQN----LVLSP 368
           L +  + E D+G Y C  +  + AV +        ++TV+  P   + P +    L +  
Sbjct: 673 LVVRRLVETDAGIYTCTVR--ITAVSYEEWPTKIGNLTVQVPPS--IKPGDTTAVLQIEQ 506

Query: 369 GENGTLICRANGNPKPRISWLTNG---VPIEIALDDPSRKIDGDTIIFSNVQESSSAVYQ 425
           G+N TL+C A+G P P I+W  +    +PI +A      +    T+  +NV      VY+
Sbjct: 505 GQNSTLVCAASGIPAPNITWTRSDGGFLPIGVA------QFRSATLPMNNVTVRDMGVYR 344

Query: 426 CNASN 430
           C A N
Sbjct: 343 CVADN 329

 Score = 22.7 bits (47), Expect(2) = 3e-04,   Method: Compositional matrix adjust.
 Identities = 8/17 (47%), Positives = 10/17 (58%)
 Frame = -3

Query: 466 ALLDCAFFGSPMPTIEW 482
           A L+C   G P PT+ W
Sbjct: 221 ANLECIVKGHPEPTVTW 171

 Score = 32.7 bits (73), Expect = 0.96,   Method: Compositional matrix adjust.
 Identities = 22/70 (31%), Positives = 34/70 (48%)
 Frame = -1

Query: 52  IDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGSGTLVINIMSEGKAETY 111
           I+  +N  + C A G P P+ +WTR+   F     P+   +  S TL +N ++       
Sbjct: 514 IEQGQNSTLVCAASGIPAPNITWTRSDGGF----LPIGVAQFRSATLPMNNVTVRDM--- 356

Query: 112 EGVYQCTARN 121
            GVY+C A N
Sbjct: 355 -GVYRCVADN 329

 Score = 30.8 bits (68), Expect = 3.4,   Method: Compositional matrix adjust.
 Identities = 35/145 (24%), Positives = 53/145 (36%), Gaps = 23/145 (15%)
 Frame = -1

Query: 404 RKIDGD----TIIFSNVQESSSAVYQCNAS------NKYGYLLANAFVNVLAEPPRILTS 453
           +++ GD     ++   + E+ + +Y C          ++   + N  V V   PP I   
Sbjct: 706 KRLSGDRETYMLVVRRLVETDAGIYTCTVRITAVSYEEWPTKIGNLTVQV---PPSIKPG 536

Query: 454 ANT-LYQVIANRPALLDCAFFGSPMPTIEWFKGTKGSALHEDIYVLHDNGTLEIPVAQKD 512
             T + Q+   + + L CA  G P P I W +               D G L I VAQ  
Sbjct: 535 DTTAVLQIEQGQNSTLVCAASGIPAPNITWTRS--------------DGGFLPIGVAQFR 398

Query: 513 ST------------GTYTCVARNKL 525
           S             G Y CVA N +
Sbjct: 397 SATLPMNNVTVRDMGVYRCVADNNI 323
>37675
          Length = 741

 Score = 45.8 bits (107), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 26/84 (30%), Positives = 41/84 (48%), Gaps = 3/84 (3%)
 Frame = +2

Query: 348 SVTVKAAPYWIVAPQNLVLSPGENGTLICRANGNPKPRISWLTNGVPIEIALDDPSR--- 404
           ++ V+  P   V+P +L+     N  + C A G PKP ISWL N VPI    +DP     
Sbjct: 50  ALKVQMPPVVKVSPHSLIYPARLNAKMKCHAEGVPKPTISWLFNNVPIS---EDPQHYDL 220

Query: 405 KIDGDTIIFSNVQESSSAVYQCNA 428
           +   + ++  N  +  +  Y+C A
Sbjct: 221 ESANELLVVYNAGDQDTGAYKCVA 292

 Score = 43.1 bits (100), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 30/93 (32%), Positives = 45/93 (48%)
 Frame = +2

Query: 28  SALDVPLDLVQPPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDP 87
           S+L V    VQ P + + SP   I   R N  ++C A+G P P+ SW  N     I +DP
Sbjct: 32  SSLQVHALKVQMPPVVKVSPHSLIYPARLNAKMKCHAEGVPKPTISWLFNNV--PISEDP 205

Query: 88  LVTMKPGSGTLVINIMSEGKAETYEGVYQCTAR 120
                  +  L++ + + G  +T  G Y+C AR
Sbjct: 206 QHYDLESANELLV-VYNAGDQDT--GAYKCVAR 295

 Score = 33.9 bits (76), Expect = 0.38,   Method: Compositional matrix adjust.
 Identities = 15/56 (26%), Positives = 31/56 (55%), Gaps = 2/56 (3%)
 Frame = +2

Query: 284 LECIAEGLPTPIIYWIKEDGMLPANRTFY--RNFKKTLQITHVSEADSGNYQCIAK 337
           ++C AEG+P P I W+  +  +  +   Y   +  + L + +  + D+G Y+C+A+
Sbjct: 128 MKCHAEGVPKPTISWLFNNVPISEDPQHYDLESANELLVVYNAGDQDTGAYKCVAR 295

 Score = 32.0 bits (71), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 18/49 (36%), Positives = 22/49 (44%), Gaps = 3/49 (6%)
 Frame = +2

Query: 571 PTIMWLKDN---GELPNDERFSTDKDHLVVSDVKDDDGGTYTCTANTTL 616
           PTI WL +N    E P      +  + LVV +  D D G Y C A   L
Sbjct: 158 PTISWLFNNVPISEDPQHYDLESANELLVVYNAGDQDTGAYKCVARIRL 304

 Score = 31.2 bits (69), Expect = 3.0,   Method: Compositional matrix adjust.
 Identities = 32/104 (30%), Positives = 41/104 (39%), Gaps = 2/104 (1%)
 Frame = +2

Query: 424 YQCNASNKYGYLLANAFVNVLAEPPRILTSANTL-YQVIANRPALLDCAFFGSPMPTIEW 482
           Y C  S     L  +A    +  PP +  S ++L Y    N  A + C   G P PTI W
Sbjct: 5   YSCEDSTDPSSLQVHALK--VQMPPVVKVSPHSLIYPARLN--AKMKCHAEGVPKPTISW 172

Query: 483 FKGTKGSALHEDIYVLHD-NGTLEIPVAQKDSTGTYTCVARNKL 525
                  +     Y L   N  L +  A    TG Y CVAR +L
Sbjct: 173 LFNNVPISEDPQHYDLESANELLVVYNAGDQDTGAYKCVARIRL 304
>17679
          Length = 509

 Score = 44.7 bits (104), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 37/126 (29%), Positives = 51/126 (40%), Gaps = 10/126 (7%)
 Frame = +3

Query: 837 DLPMVAPGNVRVSVVNSTLAEVHWDPVPPKSVRGHLQGYRIYY----------WKTQSSS 886
           + P  AP NVR    +ST   V W    P+   G +QGYR++Y          W+ Q   
Sbjct: 120 EAPGTAPRNVRARAASSTTIVVSWS--EPEIPNGIIQGYRVFYTRKPEEPVFFWEQQEVK 293

Query: 887 KRNRRHIEKKILTFQGTKTHGMLPGLQPYSHYALNVRVVNGKGEGPASTDRGFHTPEGVP 946
             NR       LT         + GL P   Y +++   +  G GP S      T +GVP
Sbjct: 294 NDNR-------LT--------TISGLDPNQTYTISILAYSSIGPGPMSHPIQVLTTQGVP 428

Query: 947 SAPSSL 952
             P +L
Sbjct: 429 YQPLNL 446
>17229
          Length = 487

 Score = 44.3 bits (103), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 37/125 (29%), Positives = 53/125 (42%), Gaps = 1/125 (0%)
 Frame = +1

Query: 811 YLIKVQALNDVGFAPEPAAVMGHSGEDLPMVAPGNVRVSVVNSTLAEVHWDPVPPKSVRG 870
           Y I+V A    G  P    +   +   LP   P  +R   +NST   V WD   PK  RG
Sbjct: 91  YYIQVSAKTVHGEGPRTPTIQTKTLPFLPG-EPRKLRAETINSTGIFVEWDE--PKDSRG 261

Query: 871 HLQGYRIYYWKTQSSSKRNRRHIEKKIL-TFQGTKTHGMLPGLQPYSHYALNVRVVNGKG 929
            ++GY +YY K   S       + +++  T  G     ++ GL   S Y + V     KG
Sbjct: 262 KIRGYYVYYVKVNGSRDEPPSGLTEQVHDTVSGRVKEAVIIGLDADSRYRVQVAGYTRKG 441

Query: 930 EGPAS 934
           +G  S
Sbjct: 442 DGRRS 456

 Score = 34.3 bits (77), Expect = 0.29,   Method: Compositional matrix adjust.
 Identities = 31/138 (22%), Positives = 49/138 (35%), Gaps = 5/138 (3%)
 Frame = +1

Query: 909  LPGLQPYSHYALNVRVVNGKGEGPASTDRGFHTPEGVPSAPSSLKIVNPTLDSLTLEWDP 968
            L  L P + Y + V      GEGP +      T   +P  P  L+        + +EWD 
Sbjct: 64   LHDLTPDTIYYIQVSAKTVHGEGPRTPTIQTKTLPFLPGEPRKLRAETINSTGIFVEWDE 243

Query: 969  PSHPNGILTEYILQYQPINSTHE-----LGPLVDLKIPANKTRWTLKNLNFSTRYKFYFY 1023
            P    G +  Y + Y  +N + +     L   V   +        +  L+  +RY+    
Sbjct: 244  PKDSRGKIRGYYVYYVKVNGSRDEPPSGLTEQVHDTVSGRVKEAVIIGLDADSRYRVQVA 423

Query: 1024 AQTSVGPGSQITEEAITT 1041
              T  G G +     I T
Sbjct: 424  GYTRKGDGRRSKSLVIDT 477
>34811
          Length = 613

 Score = 32.7 bits (73), Expect(2) = 8e-04,   Method: Compositional matrix adjust.
 Identities = 42/160 (26%), Positives = 57/160 (35%), Gaps = 14/160 (8%)
 Frame = +1

Query: 304 MLPANRTFYRNFKKTLQITHVSEADSGNYQCIAKNAL------------GAVHHTISVTV 351
            LP  R    N  + L    +  AD+GNY C A + L            G    TI+V  
Sbjct: 31  FLPNGRRQKSN-SEVLSFPQIRRADAGNYSCKASSLLKVPGVGSTETVFGQGFTTINVQY 207

Query: 352 KAAPYWIVAPQNLVLSPGENGTLICRA--NGNPKPRISWLTNGVPIEIALDDPSRKIDGD 409
                 I    N+ +  G+   L C A   G P+ R  W  NG            + D +
Sbjct: 208 APGAASIDKIDNIDV--GQRLQLTCSAAPQGFPEARFKWHRNGA--------EQSQTDAN 357

Query: 410 TIIFSNVQESSSAVYQCNASNKYGYLLANAFVNVLAEPPR 449
            +I S    S +AVY C   N  G          + EPP+
Sbjct: 358 YVIXSTAL-SDTAVYSCTPYNIAGEGAPANISVSINEPPQ 474

 Score = 29.3 bits (64), Expect(2) = 8e-04,   Method: Compositional matrix adjust.
 Identities = 14/37 (37%), Positives = 19/37 (51%), Gaps = 1/37 (2%)
 Frame = +3

Query: 457 LYQVIAN-RPALLDCAFFGSPMPTIEWFKGTKGSALH 492
           + + I+N +P  L C   G P P IEWFK     +L 
Sbjct: 501 ITRTISNTQPLTLTCRGQGRPQPIIEWFKDDMTESLQ 611
>11855
          Length = 1574

 Score = 42.7 bits (99), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 50/207 (24%), Positives = 73/207 (35%), Gaps = 49/207 (23%)
 Frame = +1

Query: 290 GLPTPIIYWIKEDGMLPANRTF---------YRNF--------------KKTLQITHVSE 326
           G P P I+W+K DG+     T+         Y +               K  L +   + 
Sbjct: 1   GSPVPTIHWLK-DGVRLTQSTYETVDDESALYEDLASDPGQPRLRLSSTKSRLYLDCPTS 177

Query: 327 ADSGNYQCIAKNALGAVHHTISVTVKAAPY---------------------WIVAPQNLV 365
            D G Y C+A+        +  V V    Y                     W V+   L 
Sbjct: 178 QDEGEYTCVAETPFKRRVQSTIVKVDTRHYSPDVTCMSKRGSRGEPARVYMWTVSRLELE 357

Query: 366 LSPGENGTLICRANGNPKPRISWL---TNGVPIEIALDDPSRKIDGDTIIFSNVQESSSA 422
            +  +   L CRA+G P+P I+W     N +P        S  ++GD II       +  
Sbjct: 358 TTTVQ---LFCRASGYPEPTITWYDGRNNSLPDNSG--QFSIAVNGDLIIRDISWSENMG 522

Query: 423 VYQCNASNKYGYLLANAFV--NVLAEP 447
           VY+C A N+ G     AF+    L EP
Sbjct: 523 VYRCVAENELGSHSVQAFLYPTTLDEP 603

 Score = 35.8 bits (81), Expect = 0.11,   Method: Compositional matrix adjust.
 Identities = 23/69 (33%), Positives = 33/69 (47%), Gaps = 2/69 (2%)
 Frame = +1

Query: 468 LDCAFFGSPMPTIEWFKGTKGSA-LHEDIYVLHDNGTLEI-PVAQKDSTGTYTCVARNKL 525
           L C   G P PTI W+ G   S   +   + +  NG L I  ++  ++ G Y CVA N+L
Sbjct: 373 LFCRASGYPEPTITWYDGRNNSLPDNSGQFSIAVNGDLIIRDISWSENMGVYRCVAENEL 552

Query: 526 GMAKNEVHL 534
           G    +  L
Sbjct: 553 GSHSVQAFL 579

 Score = 35.0 bits (79), Expect = 0.18,   Method: Compositional matrix adjust.
 Identities = 24/70 (34%), Positives = 34/70 (48%), Gaps = 3/70 (4%)
 Frame = +1

Query: 276 ELRGNVLSLECIAEGLPTPIIYWIK-EDGMLPANR-TFYRNFKKTLQITHVSEADS-GNY 332
           EL    + L C A G P P I W    +  LP N   F       L I  +S +++ G Y
Sbjct: 349 ELETTTVQLFCRASGYPEPTITWYDGRNNSLPDNSGQFSIAVNGDLIIRDISWSENMGVY 528

Query: 333 QCIAKNALGA 342
           +C+A+N LG+
Sbjct: 529 RCVAENELGS 558

 Score = 31.2 bits (69), Expect = 3.0,   Method: Compositional matrix adjust.
 Identities = 53/189 (28%), Positives = 76/189 (40%), Gaps = 46/189 (24%)
 Frame = +1

Query: 474 GSPMPTIEWFK-GTK-----------GSALHEDIYV------LHDNGT-----LEIPVAQ 510
           GSP+PTI W K G +            SAL+ED+        L  + T     L+ P +Q
Sbjct: 1   GSPVPTIHWLKDGVRLTQSTYETVDDESALYEDLASDPGQPRLRLSSTKSRLYLDCPTSQ 180

Query: 511 KDSTGTYTCVARNKLGMAKNEVHLEI-KDPTRIIKQPEYAVVQRGSK-------VSFECR 562
            +  G YTCVA       K  V   I K  TR        + +RGS+       +    R
Sbjct: 181 DE--GEYTCVAETPF---KRRVQSTIVKVDTRHYSPDVTCMSKRGSRGEPARVYMWTVSR 345

Query: 563 VKHDHTLI-----------PTIMWLK-DNGELP-NDERFSTDKD-HLVVSDVK-DDDGGT 607
           ++ + T +           PTI W    N  LP N  +FS   +  L++ D+   ++ G 
Sbjct: 346 LELETTTVQLFCRASGYPEPTITWYDGRNNSLPDNSGQFSIAVNGDLIIRDISWSENMGV 525

Query: 608 YTCTANTTL 616
           Y C A   L
Sbjct: 526 YRCVAENEL 552
>36700
          Length = 595

 Score = 41.6 bits (96), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 26/106 (24%), Positives = 42/106 (39%), Gaps = 7/106 (6%)
 Frame = +1

Query: 466 ALLDCAFFG------SPMPTIEWFKGTKGSALHEDIYVLHDNG-TLEIPVAQKDSTGTYT 518
           A L+C F G      + +P I W++ +         + + DNG  L I    +    TYT
Sbjct: 13  ARLECVFSGYSSTPNNQVPAITWWETSTDQISTGGRFSIEDNGRVLVIDNVDEQDEKTYT 192

Query: 519 CVARNKLGMAKNEVHLEIKDPTRIIKQPEYAVVQRGSKVSFECRVK 564
           C   N  G     +HL +  P   ++  +   V +G    F C  +
Sbjct: 193 CKGENPAGSHSGNLHLNVTSPPIFMQHLQSLTVPQGKDAYFNCVTR 330
>29932
          Length = 748

 Score = 39.7 bits (91), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 34/165 (20%), Positives = 62/165 (37%), Gaps = 1/165 (0%)
 Frame = +3

Query: 424 YQCNASNKYGYLLANAFVNVLAEP-PRILTSANTLYQVIANRPALLDCAFFGSPMPTIEW 482
           Y+CNA +  G ++      ++  P P+I    N   +V A+R   + C    +    ++W
Sbjct: 18  YRCNAIDPRGSIVTFVVRELVLLPLPQITFRPNIPLEVEADRNIEIYCDVTNARPENVQW 197

Query: 483 FKGTKGSALHEDIYVLHDNGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDPTRI 542
                   L   +++  D   L          G Y+C A NK G       + ++ PT  
Sbjct: 198 -ATDNNRPLPGSVHI--DGQILRFVAITPADAGGYSCTASNKYGTNSKTAQVVVRPPTFY 368

Query: 543 IKQPEYAVVQRGSKVSFECRVKHDHTLIPTIMWLKDNGELPNDER 587
            +QP+  + +R    S +      H+++         G    D R
Sbjct: 369 TQQPQSELQERREGDSIQHVAASPHSVVSIAAMFSSTGTARMDAR 503

 Score = 32.0 bits (71), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 14/47 (29%), Positives = 23/47 (48%)
 Frame = +3

Query: 317 KTLQITHVSEADSGNYQCIAKNALGAVHHTISVTVKAAPYWIVAPQN 363
           + L+   ++ AD+G Y C A N  G    T  V V+   ++   PQ+
Sbjct: 246 QILRFVAITPADAGGYSCTASNKYGTNSKTAQVVVRPPTFYTQQPQS 386

 Score = 30.4 bits (67), Expect = 4.3,   Method: Compositional matrix adjust.
 Identities = 18/50 (36%), Positives = 23/50 (46%)
 Frame = +3

Query: 403 SRKIDGDTIIFSNVQESSSAVYQCNASNKYGYLLANAFVNVLAEPPRILT 452
           S  IDG  + F  +  + +  Y C ASNKYG     A   V+  PP   T
Sbjct: 228 SVHIDGQILRFVAITPADAGGYSCTASNKYGTNSKTA--QVVVRPPTFYT 371
>18345
          Length = 461

 Score = 39.3 bits (90), Expect = 0.010,   Method: Compositional matrix adjust.
 Identities = 28/115 (24%), Positives = 43/115 (37%), Gaps = 3/115 (2%)
 Frame = +1

Query: 319 LQITHVSEADSGNYQCIAKNALGAVHHTISVTVKAAPYWIV-APQNLVLSPGENGTLICR 377
           L I HV   D+G Y+C        +     V           +P  + L  G+  TL+C 
Sbjct: 4   LLIRHVRLNDTGVYECRINTQPSQIKQVTLVVQVPPVVLSEGSPDRVSLKEGDTATLVCN 183

Query: 378 ANGNPKPRISWLTNGVPIEIALDDPSRKI--DGDTIIFSNVQESSSAVYQCNASN 430
             G P P ++W          LD    ++   G  ++  NV      +Y+C A N
Sbjct: 184 VTGVPSPDVTWYKRNTR---QLDAQKERVGSTGPVLVMYNVTRHCDDIYECYADN 339

 Score = 32.7 bits (73), Expect = 0.87,   Method: Compositional matrix adjust.
 Identities = 26/90 (28%), Positives = 40/90 (44%), Gaps = 2/90 (2%)
 Frame = +1

Query: 268 EGNESHKEELRGNVLSLECIAEGLPTPIIYWIKEDG-MLPANRTFYRNFKKTLQITHVSE 326
           EG+        G+  +L C   G+P+P + W K +   L A +    +    L + +V+ 
Sbjct: 124 EGSPDRVSLKEGDTATLVCNVTGVPSPDVTWYKRNTRQLDAQKERVGSTGPVLVMYNVTR 303

Query: 327 ADSGNYQCIAKNAL-GAVHHTISVTVKAAP 355
                Y+C A N +  AV   I VTV  AP
Sbjct: 304 HCDDIYECYADNGVPPAVTKAIRVTVDYAP 393
>25766
          Length = 469

 Score = 38.9 bits (89), Expect = 0.012,   Method: Compositional matrix adjust.
 Identities = 20/77 (25%), Positives = 37/77 (48%), Gaps = 1/77 (1%)
 Frame = +1

Query: 313 RNFKKTLQITHVSEADSGNYQCIAKNALGAVHHTIS-VTVKAAPYWIVAPQNLVLSPGEN 371
           R +   LQI  V+ AD+G Y+C+  ++ G      + + + + P   V  +N     G +
Sbjct: 49  REYDGILQIPRVTAADAGRYRCVITSSEGITSEGFATLRISSPPVVSVKQRNENRQVGSS 228

Query: 372 GTLICRANGNPKPRISW 388
               C  +G+P P++ W
Sbjct: 229 VKFHCDVSGDPVPQVRW 279

 Score = 33.1 bits (74), Expect(2) = 0.016,   Method: Compositional matrix adjust.
 Identities = 23/78 (29%), Positives = 33/78 (42%), Gaps = 1/78 (1%)
 Frame = +1

Query: 501 NGTLEIPVAQKDSTGTYTCVARNKLGM-AKNEVHLEIKDPTRIIKQPEYAVVQRGSKVSF 559
           +G L+IP       G Y CV  +  G+ ++    L I  P  +  +      Q GS V F
Sbjct: 58  DGILQIPRVTAADAGRYRCVITSSEGITSEGFATLRISSPPVVSVKQRNENRQVGSSVKF 237

Query: 560 ECRVKHDHTLIPTIMWLK 577
            C V  D   +P + W K
Sbjct: 238 HCDVSGDP--VPQVRWEK 285

 Score = 24.6 bits (52), Expect(2) = 0.016,   Method: Composition-based stats.
 Identities = 11/38 (28%), Positives = 22/38 (57%)
 Frame = +3

Query: 577 KDNGELPNDERFSTDKDHLVVSDVKDDDGGTYTCTANT 614
           K++G+LP   +       L + +++ +D G Y CTA++
Sbjct: 282 KESGQLPAQHQIRNGI--LTLYNIQKEDEGRYICTASS 389
>07945
          Length = 2023

 Score = 38.9 bits (89), Expect = 0.014,   Method: Compositional matrix adjust.
 Identities = 35/104 (33%), Positives = 43/104 (41%), Gaps = 1/104 (0%)
 Frame = -3

Query: 634  PAPIYDVPNPPFDLELTNQLDKSVQLTWTPGDDNNS-PITKFIIEYEDAMHDAGLWRHQA 692
            PAP    P PP     T+    S+ L+W P   N+S  I  + +E        G      
Sbjct: 1727 PAPPRGKPCPPSQPVATDITHNSLTLSWQPPRRNSSDTIYAYTVEKTXPSDXKGWTIVTT 1548

Query: 693  EVSGTQTTAQLKLSPYVNYSFRVMAENSIGRSMPSEASEQYLTK 736
               G Q   + KLSP   Y FRV AEN  G S  S  S+   TK
Sbjct: 1547 SCQGNQYQVK-KLSPSSQYVFRVRAENIHGVSKGSRPSDVVETK 1419
>11788
          Length = 569

 Score = 38.1 bits (87), Expect = 0.020,   Method: Compositional matrix adjust.
 Identities = 27/121 (22%), Positives = 50/121 (41%)
 Frame = +1

Query: 811 YLIKVQALNDVGFAPEPAAVMGHSGEDLPMVAPGNVRVSVVNSTLAEVHWDPVPPKSVRG 870
           Y + VQ  N  G +        ++  + P+  P  V+VS       +V W  V    +  
Sbjct: 154 YWVTVQVFNTAGLSRPSGCNYMNTNYEAPLHYPEYVQVSSHGPESVQVFWRGVSTIQIES 333

Query: 871 HLQGYRIYYWKTQSSSKRNRRHIEKKILTFQGTKTHGMLPGLQPYSHYALNVRVVNGKGE 930
            + GY+I+YW    + +  +  +  K+ +       G+L G++    Y L V   +  G+
Sbjct: 334 PVSGYKIWYWPYTDNIRTAKVAVFPKVFS-------GVLHGIERDKIYKLRVLGTSDGGD 492

Query: 931 G 931
           G
Sbjct: 493 G 495
>32888
          Length = 418

 Score = 28.9 bits (63), Expect(2) = 0.030,   Method: Composition-based stats.
 Identities = 14/37 (37%), Positives = 17/37 (45%)
 Frame = -2

Query: 316 KKTLQITHVSEADSGNYQCIAKNALGAVHHTISVTVK 352
           K  L I  +   D GNY CI  N  G +  T  V V+
Sbjct: 123 KYKLTIKSLGAEDKGNYTCIVSNTEGQIDWTFYVDVE 13

 Score = 27.7 bits (60), Expect(2) = 0.030,   Method: Compositional matrix adjust.
 Identities = 10/25 (40%), Positives = 15/25 (60%)
 Frame = -3

Query: 276 ELRGNVLSLECIAEGLPTPIIYWIK 300
           E  G  + L+C A+G P+P + W K
Sbjct: 242 EDEGQTVRLDCRAKGKPSPKVTWYK 168

 Score = 32.3 bits (72), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 16/43 (37%), Positives = 23/43 (53%)
 Frame = -3

Query: 53  DPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGS 95
           D  + + + C AKGKP P  +W +NG H   + D  V +K  S
Sbjct: 239 DEGQTVRLDCRAKGKPSPKVTWYKNG-HIITNGDDRVEIKSTS 114

 Score = 30.8 bits (68), Expect = 3.2,   Method: Compositional matrix adjust.
 Identities = 11/24 (45%), Positives = 15/24 (62%)
 Frame = -3

Query: 369 GENGTLICRANGNPKPRISWLTNG 392
           G+   L CRA G P P+++W  NG
Sbjct: 233 GQTVRLDCRAKGKPSPKVTWYKNG 162
>12764
          Length = 1055

 Score = 37.7 bits (86), Expect = 0.033,   Method: Compositional matrix adjust.
 Identities = 22/69 (31%), Positives = 35/69 (50%)
 Frame = +1

Query: 282 LSLECIAEGLPTPIIYWIKEDGMLPANRTFYRNFKKTLQITHVSEADSGNYQCIAKNALG 341
           L L CI +G P P +   +++G    N T       TL +T++S +D+G Y C   N + 
Sbjct: 280 LDLTCITQGNPLPFLVEWRQEG---ENTTLA--TGNTLTLTNLSLSDTGTYTCTGYNTVV 444

Query: 342 AVHHTISVT 350
            V+ T S +
Sbjct: 445 GVNKTNSAS 471
>05091
          Length = 1556

 Score = 36.6 bits (83), Expect = 0.066,   Method: Compositional matrix adjust.
 Identities = 39/93 (41%), Positives = 48/93 (51%), Gaps = 3/93 (3%)
 Frame = -1

Query: 1143 RRNKGGKYPVKEKEDAHA-DPEIQPMKEDDGTFGEYSDAE-DHKPLKKGSRTPSDRTVKK 1200
            R+   G YPV  KE A   DPE + MK  D  F E S A+ D  P KK      D     
Sbjct: 1118 RKMLEGAYPVDRKEVAAGLDPEKE-MK--DSGFNELSRADYDFLPEKKQPNLDFDEIPMG 948

Query: 1201 EDSDDSLVDYGEGVNGQFNEDGSFIGQYS-GKK 1232
            +D   +  +YG+  +  FNEDGSFIG Y+ GKK
Sbjct: 947  DDDSFASDEYGD-EDACFNEDGSFIGVYAKGKK 852
>27666
          Length = 873

 Score = 35.8 bits (81), Expect = 0.11,   Method: Compositional matrix adjust.
 Identities = 25/79 (31%), Positives = 38/79 (48%), Gaps = 8/79 (10%)
 Frame = +1

Query: 318 TLQITHVSEADSGNYQCIAK----NALGAVHHTISVTVKAAPYWIVAP---QNLV-LSPG 369
           TL I  + + D+G Y C  K    N L  V    ++TV+  P   + P     LV +   
Sbjct: 391 TLVIRRLRQQDAGTYVCQVKIQNENILSQVQKIGTLTVQVPPK--IRPGETTTLVEIDQN 564

Query: 370 ENGTLICRANGNPKPRISW 388
           +N +L+C + G P P I+W
Sbjct: 565 QNSSLVCSSTGIPAPNITW 621

 Score = 35.4 bits (80), Expect = 0.16,   Method: Compositional matrix adjust.
 Identities = 41/181 (22%), Positives = 68/181 (37%), Gaps = 5/181 (2%)
 Frame = +1

Query: 165 IGLPPAIIFWMDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTRED---YICYARFNHTQT 221
           I +  A+   ++     L + E V  G    L F+ V+    ++D   Y+C  +  +   
Sbjct: 289 ISMDKAVTLQINQMIGGLRKFEIVQHGPPDRLTFTLVIRRLRQQDAGTYVCQVKIQNENI 468

Query: 222 IQQKQPISLKVISVDELNDTIAANLSDTEFYGAKSSKERPPTFLTPEGNESHKEELRGNV 281
           + Q Q I    + V                         PP  + P    +  E  +   
Sbjct: 469 LSQVQKIGTLTVQV-------------------------PPK-IRPGETTTLVEIDQNQN 570

Query: 282 LSLECIAEGLPTPIIYWIKEDG-MLPANRTFYRNFK-KTLQITHVSEADSGNYQCIAKNA 339
            SL C + G+P P I W + DG  LP   T Y  F+ + L +   +    G Y+C+A N 
Sbjct: 571 SSLVCSSTGIPAPNITWTRLDGRALP---TGYSQFRGRELPLNGATVDHMGVYRCVANNN 741

Query: 340 L 340
           +
Sbjct: 742 I 744

 Score = 34.3 bits (77), Expect = 0.31,   Method: Compositional matrix adjust.
 Identities = 30/120 (25%), Positives = 49/120 (40%), Gaps = 4/120 (3%)
 Frame = +1

Query: 410 TIIFSNVQESSSAVYQCNASNKYGYLLANA---FVNVLAEPPRIL-TSANTLYQVIANRP 465
           T++   +++  +  Y C    +   +L+         +  PP+I      TL ++  N+ 
Sbjct: 391 TLVIRRLRQQDAGTYVCQVKIQNENILSQVQKIGTLTVQVPPKIRPGETTTLVEIDQNQN 570

Query: 466 ALLDCAFFGSPMPTIEWFKGTKGSALHEDIYVLHDNGTLEIPVAQKDSTGTYTCVARNKL 525
           + L C+  G P P I W +   G AL    Y       L +  A  D  G Y CVA N +
Sbjct: 571 SSLVCSSTGIPAPNITWTR-LDGRALPTG-YSQFRGRELPLNGATVDHMGVYRCVANNNI 744

 Score = 29.6 bits (65), Expect = 7.1,   Method: Compositional matrix adjust.
 Identities = 30/103 (29%), Positives = 41/103 (39%), Gaps = 1/103 (0%)
 Frame = +1

Query: 20  ILFLCQMISALDVPLDLVQPPTITQQSPKDYI-IDPRENIVIQCEAKGKPPPSFSWTRNG 78
           IL   Q I  L V +    PP I        + ID  +N  + C + G P P+ +WTR  
Sbjct: 466 ILSQVQKIGTLTVQV----PPKIRPGETTTLVEIDQNQNSSLVCSSTGIPAPNITWTR-- 627

Query: 79  THFDIDKDPLVTMKPGSGTLVINIMSEGKAETYEGVYQCTARN 121
              D    P    +     L +N    G    + GVY+C A N
Sbjct: 628 --LDGRALPTGYSQFRGRELPLN----GATVDHMGVYRCVANN 738
>20244
          Length = 452

 Score = 28.5 bits (62), Expect(2) = 0.19,   Method: Compositional matrix adjust.
 Identities = 23/65 (35%), Positives = 29/65 (44%), Gaps = 4/65 (6%)
 Frame = -2

Query: 332 YQCI-AKNALGA---VHHTISVTVKAAPYWIVAPQNLVLSPGENGTLICRANGNPKPRIS 387
           Y C+ A N LG        + VTV A     + PQN   +PG      C   G P P ++
Sbjct: 241 YLCLLASNGLGEPVRREVELQVTVNAEAVIGLDPQN-SYTPGSTIAFNCSVQGYPTPNVT 65

Query: 388 WLTNG 392
           W TNG
Sbjct: 64  W-TNG 53

 Score = 25.4 bits (54), Expect(2) = 0.19,   Method: Composition-based stats.
 Identities = 10/23 (43%), Positives = 12/23 (52%)
 Frame = -1

Query: 276 ELRGNVLSLECIAEGLPTPIIYW 298
           +L G +  L C A G P P I W
Sbjct: 407 DLNGGIAVLRCFATGNPAPNITW 339
>06033
          Length = 1423

 Score = 35.0 bits (79), Expect = 0.21,   Method: Compositional matrix adjust.
 Identities = 38/88 (43%), Positives = 46/88 (52%), Gaps = 3/88 (3%)
 Frame = -3

Query: 1148 GKYPVKEKEDAHA-DPEIQPMKEDDGTFGEYSDAE-DHKPLKKGSRTPSDRTVKKEDSDD 1205
            G YPV  KE A   DPE + MK  D  F E S A+ D  P KK      D     +D   
Sbjct: 908  GAYPVDRKEVAAGLDPEKE-MK--DSGFNELSRADYDFLPEKKQPNLDFDEIPMGDDDSF 738

Query: 1206 SLVDYGEGVNGQFNEDGSFIGQYS-GKK 1232
            +  +YG+  +  FNEDGSFIG Y+ GKK
Sbjct: 737  ASDEYGD-EDACFNEDGSFIGVYAKGKK 657
>19356
          Length = 451

 Score = 34.7 bits (78), Expect = 0.27,   Method: Compositional matrix adjust.
 Identities = 20/56 (35%), Positives = 27/56 (48%), Gaps = 2/56 (3%)
 Frame = -2

Query: 479 TIEWFKGTKGSALHEDIYVLHDNG--TLEIPVAQKDSTGTYTCVARNKLGMAKNEV 532
            IEWFK  +         ++ D G   L+I     + TG Y C ARNK G A++ V
Sbjct: 183 VIEWFKNGRPLNNGCRFNIVFDRGFAILDIIGVISEDTGDYFCFARNKAGQAQSNV 16
>04057
          Length = 1327

 Score = 33.5 bits (75), Expect = 0.50,   Method: Compositional matrix adjust.
 Identities = 19/51 (37%), Positives = 27/51 (52%)
 Frame = +1

Query: 944 GVPSAPSSLKIVNPTLDSLTLEWDPPSHPNGILTEYILQYQPINSTHELGP 994
           G P APS++KI   T +   L W+PP +  G +TEY +     N+  E  P
Sbjct: 40  GFPGAPSAIKISKST-EGAHLSWEPPQNTAGKITEYSVYLAVRNANTEPKP 189
>17530
          Length = 503

 Score = 33.5 bits (75), Expect = 0.50,   Method: Compositional matrix adjust.
 Identities = 29/129 (22%), Positives = 58/129 (44%), Gaps = 5/129 (3%)
 Frame = +2

Query: 39  PPTITQQSPKDYIIDPRENIVIQCEAKG-KPPPSFSWTRNGTHFDIDKDPL-VTMKPGSG 96
           PP+IT     D + +  + +   C + G  PPP+ +WT+NG         + V     SG
Sbjct: 62  PPSITSDITGD-VFEEGQRVRFTCSSSGGNPPPTITWTKNGVQLINGVQQIGVGQTSTSG 238

Query: 97  TLVINIMSEGKAET-YEGVYQCTARNER--GAAVSNNIVVRPSRSPLWTKERLEPIVLQN 153
               N +S     + ++  Y C   N+    ++++ ++V+    SP+ T E   P +++ 
Sbjct: 239 GSTRNTVSVVMDHSDHQANYTCFVYNQVNINSSLTASVVLNVRYSPIITFEPFSPYIVRL 418

Query: 154 GQSLVLPCR 162
            +   + C+
Sbjct: 419 DRPANITCQ 445
>30103
          Length = 341

 Score = 33.1 bits (74), Expect = 0.82,   Method: Compositional matrix adjust.
 Identities = 25/83 (30%), Positives = 38/83 (45%), Gaps = 2/83 (2%)
 Frame = +1

Query: 951  SLKIVNPTLDSLTLEWDPPS--HPNGILTEYILQYQPINSTHELGPLVDLKIPANKTRWT 1008
            SLK  N +L  + L+W PP+    NG+L  Y +QY+   S    G +  +  P+    + 
Sbjct: 7    SLKFSNDSL--VLLKWRPPAARQKNGVLQSYKVQYRRKGS--RRGDVCSVITPSQDHHFF 174

Query: 1009 LKNLNFSTRYKFYFYAQTSVGPG 1031
            L ++     YK    A T  G G
Sbjct: 175  LTDVTSGQTYKVRVAAMTVNGTG 243
>29881
          Length = 416

 Score = 32.7 bits (73), Expect = 0.92,   Method: Compositional matrix adjust.
 Identities = 17/56 (30%), Positives = 26/56 (46%), Gaps = 3/56 (5%)
 Frame = -3

Query: 290 GLPTPIIYWIKEDGML---PANRTFYRNFKKTLQITHVSEADSGNYQCIAKNALGA 342
           G    +  W K+  M    P  R    N+   L +++V E D+G Y C A+N+ G 
Sbjct: 375 GAQADVTMWRKDGDMFTQGPRKRMLVNNY---LMVSNVVETDAGQYTCAARNSEGC 217
>22543
          Length = 494

 Score = 32.0 bits (71), Expect = 1.8,   Method: Composition-based stats.
 Identities = 26/65 (40%), Positives = 33/65 (50%), Gaps = 2/65 (3%)
 Frame = +1

Query: 1174 FGEYSDAE-DHKPLKKGSRTPSDRTVKKEDSDDSLVDYGEGVNGQFNEDGSFIGQYS-GK 1231
            F E S A+ D  P KK      D     +D   +  +YG+  +  FNEDGSFIG Y+ GK
Sbjct: 1    FNELSRADYDFLPEKKQPNLDFDEIPMGDDDSFASDEYGDE-DACFNEDGSFIGVYAKGK 177

Query: 1232 KEKEP 1236
            K   P
Sbjct: 178  KPGGP 192
>37263
          Length = 743

 Score = 31.6 bits (70), Expect = 2.1,   Method: Composition-based stats.
 Identities = 18/44 (40%), Positives = 26/44 (59%), Gaps = 2/44 (4%)
 Frame = -2

Query: 712 SFRVMAENSIGRSMPSEASEQYLTK--AAEPDQNPMAVEGLGTE 753
           SFR++  NS+G  + S ASE  L +  +A P ++PM    L TE
Sbjct: 382 SFRILLTNSMGCKLVSYASENCLAEPSSAPPKRSPMVSRPLTTE 251
>10921
          Length = 525

 Score = 31.2 bits (69), Expect = 2.6,   Method: Compositional matrix adjust.
 Identities = 36/125 (28%), Positives = 51/125 (40%), Gaps = 14/125 (11%)
 Frame = -2

Query: 319 LQITHVSEADSGNYQCIAKNALGAVHHTISVTVKAAPYWIVAPQNLVL------SPGENG 372
           L I +V+  D   Y C A    G+  +   +TV      I  PQNL +      +P    
Sbjct: 416 LIIVNVTLNDQAEYTCKA----GSESYFGFLTV------IDLPQNLTVQWETTPTPSSTS 267

Query: 373 TLICRAN-GNPKPRISWLTNGVPIE------IALDDPSRKIDG-DTIIFSNVQESSSAVY 424
            L C A+  +P P +SW  NGV ++       A  D S   D   T+      E   +V+
Sbjct: 266 NLSCVASRAHPPPPLSWFKNGVRLDGSRAHYYATTDHSGYGDAVSTLPLETRGEDEGSVF 87

Query: 425 QCNAS 429
            C AS
Sbjct: 86  TCEAS 72

 Score = 30.8 bits (68), Expect = 3.9,   Method: Compositional matrix adjust.
 Identities = 22/86 (25%), Positives = 33/86 (38%), Gaps = 17/86 (19%)
 Frame = -2

Query: 51  IIDPRENIVIQCE---------------AKGKPPPSFSWTRNGTHFDIDKDPL--VTMKP 93
           +ID  +N+ +Q E               ++  PPP  SW +NG   D  +      T   
Sbjct: 332 VIDLPQNLTVQWETTPTPSSTSNLSCVASRAHPPPPLSWFKNGVRLDGSRAHYYATTDHS 153

Query: 94  GSGTLVINIMSEGKAETYEGVYQCTA 119
           G G  V  +  E + E    V+ C A
Sbjct: 152 GYGDAVSTLPLETRGEDEGSVFTCEA 75
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|27261816|ref|NP_080861.1| hypothetical protein
LOC28006 [Mus musculus]
         (1334 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

11995                                                                 133   4e-31
04177                                                                  30   5.5  
21626                                                                  30   6.3  
21896                                                                  29   9.9  
>11995
          Length = 882

 Score =  133 bits (335), Expect = 4e-31,   Method: Compositional matrix adjust.
 Identities = 66/134 (49%), Positives = 85/134 (63%), Gaps = 1/134 (0%)
 Frame = +1

Query: 62  KQVDGLIQETKATHCRLHNVFNDFLMLSNTQFIENRVYDXXXXXXXXXXXXXX-XXXXXX 120
           K+VDGL+ E K T  RL+NV NDF+ML+NTQF+ENRVYD                     
Sbjct: 25  KEVDGLVHEAKLTGVRLNNVTNDFIMLANTQFVENRVYDEDVTQEAEATEEKPPEHTEKT 204

Query: 121 XXXXXIDLIPKVQEAVNYGLQVLDSAFEQLDIKAGNSDSEEDDANERVDLILEPKDLYID 180
                 DL+PKV EA+ +G+ V+D AFE+LD    +SDSE++D N +VD ILEPKD Y+ 
Sbjct: 205 REQREADLVPKVAEALKFGIDVIDQAFEKLDSHVADSDSEDEDTNYKVDPILEPKDPYVT 384

Query: 181 RPLPYLIGSKLFME 194
           R LP LIGS LF++
Sbjct: 385 RTLPCLIGSPLFLQ 426
>04177
          Length = 1620

 Score = 30.4 bits (67), Expect = 5.5,   Method: Compositional matrix adjust.
 Identities = 20/42 (47%), Positives = 23/42 (54%), Gaps = 1/42 (2%)
 Frame = -1

Query: 999  TLPGSVEAGVSFDLPAQADTLHSANKSRV-KVRGKRRPQTRA 1039
            TLPG+ +   S   PA A T  S  KS + K   KRRP TRA
Sbjct: 1071 TLPGTSDTSSSPTPPASAXTXSSREKSSMLKTTSKRRPTTRA 946
>21626
          Length = 436

 Score = 30.0 bits (66), Expect = 6.3,   Method: Composition-based stats.
 Identities = 15/32 (46%), Positives = 16/32 (50%)
 Frame = -2

Query: 378 QAPVSEELPPSPKPGKKIPAGAVSVLLGHPDV 409
           QA    ELPP P   +  P     VLLGHP V
Sbjct: 108 QAGHEPELPPDPPACQTTPPPQTCVLLGHPQV 13
>21896
          Length = 365

 Score = 29.3 bits (64), Expect = 9.9,   Method: Composition-based stats.
 Identities = 15/32 (46%), Positives = 16/32 (50%)
 Frame = -2

Query: 378 QAPVSEELPPSPKPGKKIPAGAVSVLLGHPDV 409
           QA    ELPP P   +  P     VLLGHP V
Sbjct: 190 QAGHEPELPPDPPACQTTPPPQTCVLLGHPQV 95
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|46877043|ref|NP_525026.2| engulfment and cell
motility 2, ced-12 homolog isoform 3 [Mus musculus]
         (720 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

21952                                                                 132   4e-31
28593                                                                  66   2e-23
04661                                                                  30   3.4  
>21952
          Length = 688

 Score =  132 bits (333), Expect = 4e-31,   Method: Compositional matrix adjust.
 Identities = 78/172 (45%), Positives = 115/172 (66%), Gaps = 5/172 (2%)
 Frame = -1

Query: 533 IQPEILELIKQQRLNRLCEGSSFRKIGNR--RRQERFWHCRLALNHKVLHYGDLD--DNP 588
           + PEIL +++QQRLN L EG+ F K  +R  R +++FW  RL+ N+K LHYGD    D+P
Sbjct: 688 LGPEILSVVRQQRLNYLMEGTCFPKYHSRNGRIKDKFWFWRLSPNNKSLHYGDCSETDHP 509

Query: 589 QGEVTFESLQEKIPVADIKAIVTGKDCPHMKEKSALKQNKEVLELAFSILYDPDE-TLNF 647
           +     E L  K+P+ DI+ +VTGKDCPH+  K  L++      LAFS++ + +E  + F
Sbjct: 508 K----LEDLPSKLPLVDIQRLVTGKDCPHVGGKQGLRKAGPNGRLAFSLVTEAEEDQMCF 341

Query: 648 IAPNKYEYCIWIDGLSALLGKDMSSELTKSDLDTLLSMEMKLRLLDLENIQI 699
           +A  +YEY +W DGL++LL  +MSS   + D++ LLSME+K+RLLD E +QI
Sbjct: 340 VAXTEYEYDMWCDGLNSLLSSEMSSSQVRQDMEMLLSMEIKIRLLDTEGLQI 185
>28593
          Length = 591

 Score = 66.2 bits (160), Expect(2) = 2e-23,   Method: Composition-based stats.
 Identities = 30/82 (36%), Positives = 54/82 (65%), Gaps = 4/82 (4%)
 Frame = -2

Query: 60  YVTEQTRNDIKNGTILQLAVSPSRAARQLMERTQSSSMET----RLDAMKELAKLSADVT 115
           Y+TE+ R++I+NG +L LA SP++ A+ ++ +    + +T    +LD +++L  L+ D T
Sbjct: 347 YITERNRHEIQNGAVLSLAPSPAQTAQSIIAKLSVGATKTFSEDKLDGLRQLVGLAPDST 168

Query: 116 FATEFINMDGIIVLTRLVESGT 137
           FA EFIN +G+ ++  +V  GT
Sbjct: 167 FAVEFINKNGLPIIIGIVTDGT 102

 Score = 61.6 bits (148), Expect(2) = 2e-23,   Method: Compositional matrix adjust.
 Identities = 27/60 (45%), Positives = 40/60 (66%)
 Frame = -3

Query: 5   SDIVKVAIEWPGANAQLLEIDQKRPLASIIKEVCDGWSLPNPEYYTLRYADGPQLYVTEQ 64
           ++I KVA+  PG  AQ LE DQKRPLA+II+++C  WSL +   + L+ +D  ++  T Q
Sbjct: 517 ANIRKVAVVMPGYQAQFLEFDQKRPLAAIIQDICGSWSLNDASKFALQISDSSKITRTSQ 338
>04661
          Length = 2394

 Score = 30.0 bits (66), Expect = 3.4,   Method: Compositional matrix adjust.
 Identities = 19/61 (31%), Positives = 29/61 (47%), Gaps = 9/61 (14%)
 Frame = +1

Query: 442  DRAFEEL----FGICIQLLNKTWKEMRATAEDFNKVMQVVR-----EQITRALPSKPNSL 492
            D AF  L      +CI LL + W E      D  +++Q+V      E++ R +   P+SL
Sbjct: 1120 DSAFSILRQREIDLCIALLREKWAECMVIGRDLVRILQLVARIPEFEKLWRDIFLNPSSL 1299

Query: 493  D 493
            D
Sbjct: 1300 D 1302
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|70778915|ref|NP_034963.2| moesin [Mus musculus]
         (577 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

00990                                                                 132   4e-31
17332                                                                  78   9e-15
18811                                                                  57   2e-08
13951                                                                  41   0.002
08616                                                                  32   0.96 
>00990
          Length = 3161

 Score =  132 bits (332), Expect = 4e-31,   Method: Compositional matrix adjust.
 Identities = 90/301 (29%), Positives = 153/301 (50%), Gaps = 9/301 (2%)
 Frame = +3

Query: 3   KTISVRVTTMDAE-LEFAIQPNTTGKQLFDQVVKTIGLREVWFFGLQYQD---TKAFSTW 58
           K  +  V  +D E + F +  N  G++LFD+V + + L E  +FGLQ+ D   +     W
Sbjct: 252 KGFNYEVVLLDGEHVNFELDRNAEGRELFDKVCQHLDLIEKDYFGLQFVDERISNHLKCW 431

Query: 59  LKLNKKVTAQDVRKESPLLFKFRAKFYPEDVSEELIQDITQRLFFLQVKEGILNDDIYCP 118
           L  +K+++ Q  +K  P LF F  KFYP D ++ L + +T+ L  LQ +  IL+  +   
Sbjct: 432 LSPDKRISKQ--KKGGPWLFDFALKFYPPDPTQ-LRESLTRWLVVLQTRRDILSGKLPAT 602

Query: 119 PETAVLLASYAVQSKYGDFNKEVHKSG-YLAGDKLLPQRVLEQHKLNKDQWEERIQVWHE 177
             T  +L SY VQ+  GD++   H+   Y+      P + ++          E+I   H 
Sbjct: 603 YLTQAMLGSYCVQADVGDYDPNEHRGVEYIRDTPFAPNQTIDLL--------EKIVELHR 758

Query: 178 EHRGMLREDAVLEYLKIAQDLEMYGVNYFSIKNKKGSELWLGVDALGLNIYEQNDRLTPK 237
           +H+G   ++A   +L+ A+ L MYGV+  + ++    ++ LGV A GL +Y +  R++  
Sbjct: 759 QHKGQTPDEAETNFLENAKKLAMYGVDLHAAQDVNNVDIMLGVCASGLQVYREKLRIS-- 932

Query: 238 IGFPWSEIRNISFNDKKFVIK--PIDKKAPD--FVFYAPRLRINKRILALCMGNHELYMR 293
             F W +I  IS+  ++F IK  P D  A +  F F     R+ KR+  +C+ +H  +  
Sbjct: 933 -RFVWPKILKISYKRRQFYIKVRPSDNSAMENSFCFKLATHRLAKRLWKICVEHHAFFRL 1109

Query: 294 R 294
           R
Sbjct: 1110R 1112
>17332
          Length = 473

 Score = 78.2 bits (191), Expect = 9e-15,   Method: Composition-based stats.
 Identities = 49/147 (33%), Positives = 81/147 (55%)
 Frame = +2

Query: 13  DAELEFAIQPNTTGKQLFDQVVKTIGLREVWFFGLQYQDTKAFSTWLKLNKKVTAQDVRK 72
           D++ +  ++ N  G  L ++V + + L E  +FGL++ D    + WL  NK +++Q    
Sbjct: 5   DSDHQLQVKGNWKGILLQEKVCELLNLHEKDYFGLRFIDASGQTHWLDGNKSLSSQLKGC 184

Query: 73  ESPLLFKFRAKFYPEDVSEELIQDITQRLFFLQVKEGILNDDIYCPPETAVLLASYAVQS 132
           ++P    F  KFY  D  + L ++IT+ LFFLQVK+ IL   +    + A  L +YAVQS
Sbjct: 185 QTPHKLYFGVKFYAADPCK-LREEITRYLFFLQVKQDILQGRLPVTFDEASELCAYAVQS 361

Query: 133 KYGDFNKEVHKSGYLAGDKLLPQRVLE 159
           + GDF+   H  GY++    +P +  E
Sbjct: 362 ELGDFDPRQHTDGYVSEFCFIPNQTEE 442
>18811
          Length = 478

 Score = 57.0 bits (136), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 37/115 (32%), Positives = 60/115 (52%), Gaps = 4/115 (3%)
 Frame = -2

Query: 170 ERIQVWHEEHRGMLREDAVLEYLKIAQDLEMYGVNYFSIKNKKGSELWLGVDALGLNIYE 229
           E+I   H +H+G   ++A + YL+ A+ L MYGV+  + ++    ++ LGV + GL +Y 
Sbjct: 342 EKIVELHRQHKGQTPDEAEVNYLENAKKLSMYGVDLHAAQDVNNVDIMLGVCSSGLQVYR 163

Query: 230 QNDRLTPKIGFPWSEIRNISFNDKKFVIK--PIDKKA--PDFVFYAPRLRINKRI 280
              R++    F W +I  IS+  K F +K  P D K       F  P  R+ KR+
Sbjct: 162 DKLRIS---RFVWPKIIKISYKRKHFYVKVRPADNKGLETSVSFRLPTHRLAKRL 7
>13951
          Length = 720

 Score = 40.8 bits (94), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 22/73 (30%), Positives = 39/73 (53%), Gaps = 4/73 (5%)
 Frame = -2

Query: 3   KTISVRVTTMDAE-LEFAIQPNTTGKQLFDQVVKTIGLREVWFFGLQYQD---TKAFSTW 58
           K  +  V  +D E + F +  N  G++LFD+V + + L E  +FGLQ+ D   +     W
Sbjct: 398 KGFNYEVVLLDGEHVNFELDRNAEGRELFDKVCQHLDLIEKDYFGLQFVDERISNHLKCW 219

Query: 59  LKLNKKVTAQDVR 71
           L  +K+++  + R
Sbjct: 218 LSPDKRISKTEKR 180
>08616
          Length = 2833

 Score = 31.6 bits (70), Expect = 0.96,   Method: Compositional matrix adjust.
 Identities = 22/53 (41%), Positives = 28/53 (52%), Gaps = 2/53 (3%)
 Frame = +2

Query: 170  ERIQVWHEEHRGMLREDAVLEYLKIAQDLEMYGVNYFSIK--NKKGSELWLGV 220
            +RI   H   R M   +A + Y+K  Q L  +G+ YF IK  N K  EL LGV
Sbjct: 1046 QRIMEAHANVREMSLMEAKMAYIKAWQSLPEFGITYFRIKMANSKKEEL-LGV 1201
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|7305363|ref|NP_038653.1| platelet-activating factor
acetylhydrolase, isoform 1b, beta1 subunit [Mus musculus]
         (410 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

30256                                                                 131   4e-31
00561                                                                 114   6e-26
26939                                                                 106   1e-23
17598                                                                  97   8e-21
12806                                                                  94   8e-20
17602                                                                  91   1e-18
13335                                                                  89   4e-18
12574                                                                  84   1e-16
01327                                                                  84   1e-16
03156                                                                  83   2e-16
02147                                                                  81   6e-16
27465                                                                  80   1e-15
19949                                                                  77   1e-14
02960                                                                  68   9e-12
21105                                                                  62   3e-10
12960                                                                  61   8e-10
13278                                                                  61   9e-10
18981                                                                  60   1e-09
31474                                                                  58   8e-09
01805                                                                  58   8e-09
17266                                                                  58   8e-09
19498                                                                  56   3e-08
37180                                                                  54   8e-08
19863                                                                  54   9e-08
10162                                                                  54   2e-07
03395                                                                  54   2e-07
02090                                                                  52   3e-07
27806                                                                  52   4e-07
03387                                                                  52   5e-07
27270                                                                  51   8e-07
29912                                                                  50   2e-06
13890                                                                  49   3e-06
15118                                                                  49   5e-06
01768                                                                  47   1e-05
14555                                                                  37   2e-05
15780                                                                  46   2e-05
15337                                                                  46   2e-05
19140                                                                  45   6e-05
01249                                                                  44   1e-04
11493                                                                  44   2e-04
01462                                                                  43   2e-04
00825                                                                  43   3e-04
30176                                                                  43   3e-04
21921                                                                  42   4e-04
26107                                                                  42   4e-04
20662                                                                  42   5e-04
15745                                                                  40   0.001
27681                                                                  30   0.002
16199                                                                  34   0.004
15972                                                                  39   0.004
31054                                                                  39   0.005
34005                                                                  39   0.005
11915                                                                  39   0.005
36111                                                                  38   0.007
31384                                                                  38   0.008
10264                                                                  38   0.009
04524                                                                  37   0.011
01598                                                                  37   0.014
16105                                                                  37   0.015
14500                                                                  37   0.018
25400                                                                  35   0.043
12841                                                                  35   0.064
20271                                                                  35   0.067
35695                                                                  34   0.085
30108                                                                  33   0.21 
17298                                                                  33   0.22 
38177                                                                  33   0.25 
30295                                                                  33   0.25 
30297                                                                  32   0.34 
30679                                                                  32   0.36 
31864                                                                  32   0.37 
05393                                                                  32   0.42 
07741                                                                  32   0.45 
25880                                                                  32   0.58 
13486                                                                  31   0.85 
31118                                                                  31   0.91 
04088                                                                  31   1.2  
12140                                                                  30   1.3  
21960                                                                  30   2.4  
22113                                                                  29   3.8  
13509                                                                  29   3.9  
34511                                                                  29   4.1  
33180                                                                  28   5.1  
06576                                                                  28   5.8  
17807                                                                  28   6.2  
30727                                                                  28   6.6  
35607                                                                  28   8.0  
05188                                                                  28   8.8  
>30256
          Length = 961

 Score =  131 bits (330), Expect = 4e-31,   Method: Compositional matrix adjust.
 Identities = 88/273 (32%), Positives = 139/273 (50%), Gaps = 3/273 (1%)
 Frame = +3

Query: 139 TGDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSV 198
           TG   + L GHT  V   S   +G  + S S D ++K+W+     C  T++GH   V  +
Sbjct: 9   TGRCIKNLIGHTGGVW--SSQMTGNTVISGSTDRSLKVWNADTGVCTHTLYGHSSTVRCL 182

Query: 199 AIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTV 258
           ++  +G  +VS SRD T+++W++++G+C+    GH   VR V+   DG  + S + D TV
Sbjct: 183 SL--SGKKVVSGSRDATLRVWDIESGHCLNVLLGHMAAVRCVQ--YDGKRVVSGAXDYTV 350

Query: 259 RVWVVATKECKAELREHEHVVECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDK 318
           RVW   T  C   L+ H + V  + +                       G +++SGS D 
Sbjct: 351 RVWDPDTASCLHTLQGHTNRVYSLQF----------------------DGVYVVSGSLDT 464

Query: 319 TIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTL-- 376
           +I++WDV  G  + TL+GH +   G+        ++S   D T++VWD    +C++TL  
Sbjct: 465 SIRVWDVRCGKLVHTLMGHQSLTSGLELKD--NLLVSGNADSTVKVWDVHTGKCLQTLLG 638

Query: 377 -NAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWE 408
            N H   VT L F+K   +VVT S D TVK+W+
Sbjct: 639 PNKHRSAVTCLQFNK--KFVVTCSDDGTVKLWD 731

 Score =  126 bits (317), Expect = 1e-29,   Method: Compositional matrix adjust.
 Identities = 83/259 (32%), Positives = 134/259 (51%), Gaps = 3/259 (1%)
 Frame = +3

Query: 121 SVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQ 180
           + ++S S D ++KVW+ +TG    TL GH+ +V+ +S   SGK + S S D T+++WD +
Sbjct: 75  NTVISGSTDRSLKVWNADTGVCTHTLYGHSSTVRCLSL--SGKKVVSGSRDATLRVWDIE 248

Query: 181 GFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMV 240
              C+  + GH   V  V    +G  +VS + D T+++W+  T  C+ T  GH    R+ 
Sbjct: 249 SGHCLNVLLGHMAAVRCVQY--DGKRVVSGAXDYTVRVWDPDTASCLHTLQGHTN--RVY 416

Query: 241 RPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSSISEATGSE 300
               DG  + S S D ++RVW V   +    L  H+                 S  +G E
Sbjct: 417 SLQFDGVYVVSGSLDTSIRVWDVRCGKLVHTLMGHQ-----------------SLTSGLE 545

Query: 301 TKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVG---HDNWVRGVLFHSGGKFILSCA 357
            K +      L+SG+ D T+K+WDV TG CL TL+G   H + V  + F+   KF+++C+
Sbjct: 546 LKDN-----LLVSGNADSTVKVWDVHTGKCLQTLLGPNKHRSAVTCLQFNK--KFVVTCS 704

Query: 358 DDKTLRVWDYKNKRCMKTL 376
           DD T+++WD      ++ L
Sbjct: 705 DDGTVKLWDLNTGDFIRNL 761

 Score =  105 bits (261), Expect = 4e-23,   Method: Compositional matrix adjust.
 Identities = 70/230 (30%), Positives = 115/230 (50%), Gaps = 3/230 (1%)
 Frame = +3

Query: 102 YALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHS 161
           + L GH S V  +        +VS S DAT++VWD E+G     L GH  +V+ + +D  
Sbjct: 144 HTLYGHSSTVRCLSLSG--KKVVSGSRDATLRVWDIESGHCLNVLLGHMAAVRCVQYD-- 311

Query: 162 GKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEV 221
           GK + S + D T+++WD     C+ T+ GH + V S+    +G ++VS S D +I++W+V
Sbjct: 312 GKRVVSGAXDYTVRVWDPDTASCLHTLQGHTNRVYSLQF--DGVYVVSGSLDTSIRVWDV 485

Query: 222 QTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAEL---REHEHV 278
           + G  V T  GH+     +    +  L+ S + D TV+VW V T +C   L    +H   
Sbjct: 486 RCGKLVHTLMGHQSLTSGLELKDN--LLVSGNADSTVKVWDVHTGKCLQTLLGPNKHRSA 659

Query: 279 VECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTG 328
           V C+ +  +                      F+++ S D T+K+WD++TG
Sbjct: 660 VTCLQFNKK----------------------FVVTCSDDGTVKLWDLNTG 743

 Score =  102 bits (255), Expect = 2e-22,   Method: Compositional matrix adjust.
 Identities = 65/188 (34%), Positives = 93/188 (49%)
 Frame = +3

Query: 223 TGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECI 282
           TG C+K   GH   V        G  + S S D++++VW   T  C   L  H   V C+
Sbjct: 9   TGRCIKNLIGHTGGVW--SSQMTGNTVISGSTDRSLKVWNADTGVCTHTLYGHSSTVRCL 182

Query: 283 SWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVR 342
           S +                      G  ++SGSRD T+++WD+ +G CL  L+GH   VR
Sbjct: 183 SLS----------------------GKKVVSGSRDATLRVWDIESGHCLNVLLGHMAAVR 296

Query: 343 GVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQ 402
            V +   GK ++S A D T+RVWD     C+ TL  H + V SL F     YVV+GS+D 
Sbjct: 297 CVQYD--GKRVVSGAXDYTVRVWDPDTASCLHTLQGHTNRVYSLQFD--GVYVVSGSLDT 464

Query: 403 TVKVWECR 410
           +++VW+ R
Sbjct: 465 SIRVWDVR 488
>00561
          Length = 1003

 Score =  114 bits (286), Expect = 6e-26,   Method: Compositional matrix adjust.
 Identities = 79/260 (30%), Positives = 117/260 (45%), Gaps = 10/260 (3%)
 Frame = -3

Query: 122 VMVSASEDATIKVW------DYETGDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIK 175
            ++SAS D T+ VW      D   G  ++ L GH+  + D+     G    S S D T++
Sbjct: 968 TIISASRDKTLIVWKLTRDEDTNYGYPQKRLYGHSHFISDVVLSSDGNYALSGSWDQTLR 789

Query: 176 LWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFT--GH 233
           LWD    +  R   GH  +V SVA   +   IVS SRDKTIK+W      C  T    GH
Sbjct: 788 LWDLAAGKTTRRFEGHTKDVLSVAFSADNRQIVSGSRDKTIKLWNT-LAECKFTIQEDGH 612

Query: 234 REWVRMVR--PNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYS 291
            +WV  VR  PN    +I SC  D+TV+VW +A  + K     H   +  ++ +P+    
Sbjct: 611 TDWVSCVRFSPNHSNPIIVSCGWDRTVKVWNLANCKLKNNHHGHNGYLNTVTVSPD---- 444

Query: 292 SISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGK 351
                           G    SG +D    +WD++ G  L TL  +D  +   L  S  +
Sbjct: 443 ----------------GSLCTSGGKDSKALLWDLNDGKNLYTLEHND--IINALCFSPNR 318

Query: 352 FILSCADDKTLRVWDYKNKR 371
           + L  A   ++++WD   K+
Sbjct: 317 YWLCVAYGPSIKIWDLACKK 258

 Score = 87.4 bits (215), Expect = 8e-18,   Method: Compositional matrix adjust.
 Identities = 62/253 (24%), Positives = 115/253 (45%), Gaps = 9/253 (3%)
 Frame = -3

Query: 165 LASCSADMTIKLWDFQ-------GFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIK 217
           + S S D T+ +W          G+   R ++GH H +S V +  +G++ +S S D+T++
Sbjct: 965 IISASRDKTLIVWKLTRDEDTNYGYPQKR-LYGHSHFISDVVLSSDGNYALSGSWDQTLR 789

Query: 218 MWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEH 277
           +W++  G   + F GH + V  V  + D   I S S D+T+++W     ECK  ++E  H
Sbjct: 788 LWDLAAGKTTRRFEGHTKDVLSVAFSADNRQIVSGSRDKTIKLWNTLA-ECKFTIQEDGH 612

Query: 278 V--VECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLV 335
              V C+ ++P  S                   P ++S   D+T+K+W+++         
Sbjct: 611 TDWVSCVRFSPNHS------------------NPIIVSCGWDRTVKVWNLANCKLKNNHH 486

Query: 336 GHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYV 395
           GH+ ++  V     G    S   D    +WD  + + + TL  H   + +L F     Y 
Sbjct: 485 GHNGYLNTVTVSPDGSLCTSGGKDSKALLWDLNDGKNLYTLE-HNDIINALCFSPNR-YW 312

Query: 396 VTGSVDQTVKVWE 408
           +  +   ++K+W+
Sbjct: 311 LCVAYGPSIKIWD 273

 Score = 83.6 bits (205), Expect = 1e-16,   Method: Compositional matrix adjust.
 Identities = 62/224 (27%), Positives = 104/224 (46%), Gaps = 11/224 (4%)
 Frame = -3

Query: 196  SSVAIMP-NGDHIVSASRDKTIKMWEV------QTGYCVKTFTGHREWVRMVRPNQDGTL 248
            + +A  P + D I+SASRDKT+ +W++        GY  K   GH  ++  V  + DG  
Sbjct: 1001 TQIATNPKDPDTIISASRDKTLIVWKLTRDEDTNYGYPQKRLYGHSHFISDVVLSSDGNY 822

Query: 249  IASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSSISEATGSETKKSGKPG 308
              S S DQT+R+W +A  +       H   V             +S A  ++ ++     
Sbjct: 821  ALSGSWDQTLRLWDLAAGKTTRRFEGHTKDV-------------LSVAFSADNRQ----- 696

Query: 309  PFLLSGSRDKTIKMWDVSTGMCLMTLV--GHDNWVRGVLF--HSGGKFILSCADDKTLRV 364
              ++SGSRDKTIK+W+ +   C  T+   GH +WV  V F  +     I+SC  D+T++V
Sbjct: 695  --IVSGSRDKTIKLWN-TLAECKFTIQEDGHTDWVSCVRFSPNHSNPIIVSCGWDRTVKV 525

Query: 365  WDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWE 408
            W+  N +     + H  ++ ++          +G  D    +W+
Sbjct: 524  WNLANCKLKNNHHGHNGYLNTVTVSPDGSLCTSGGKDSKALLWD 393

 Score = 80.9 bits (198), Expect = 9e-16,   Method: Compositional matrix adjust.
 Identities = 57/193 (29%), Positives = 90/193 (46%), Gaps = 4/193 (2%)
 Frame = -3

Query: 99  PEKYALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISF 158
           P+K  L GH   ++ V+     +  +S S D T+++WD   G   R  +GHT  V  ++F
Sbjct: 890 PQK-RLYGHSHFISDVVLSSDGNYALSGSWDQTLRLWDLAAGKTTRRFEGHTKDVLSVAF 714

Query: 159 DHSGKLLASCSADMTIKLWDFQGFECIRTMH--GHDHNVSSVAIMPNGDH--IVSASRDK 214
               + + S S D TIKLW+    EC  T+   GH   VS V   PN  +  IVS   D+
Sbjct: 713 SADNRQIVSGSRDKTIKLWNTLA-ECKFTIQEDGHTDWVSCVRFSPNHSNPIIVSCGWDR 537

Query: 215 TIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELRE 274
           T+K+W +          GH  ++  V  + DG+L  S   D    +W +   +    L E
Sbjct: 536 TVKVWNLANCKLKNNHHGHNGYLNTVTVSPDGSLCTSGGKDSKALLWDLNDGKNLYTL-E 360

Query: 275 HEHVVECISWAPE 287
           H  ++  + ++P 
Sbjct: 359 HNDIINALCFSPN 321

 Score = 62.0 bits (149), Expect = 4e-10,   Method: Compositional matrix adjust.
 Identities = 36/110 (32%), Positives = 58/110 (52%), Gaps = 10/110 (9%)
 Frame = -3

Query: 311 LLSGSRDKTIKMW------DVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRV 364
           ++S SRDKT+ +W      D + G     L GH +++  V+  S G + LS + D+TLR+
Sbjct: 965 IISASRDKTLIVWKLTRDEDTNYGYPQKRLYGHSHFISDVVLSSDGNYALSGSWDQTLRL 786

Query: 365 WDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVW----ECR 410
           WD    +  +    H   V S+ F      +V+GS D+T+K+W    EC+
Sbjct: 785 WDLAAGKTTRRFEGHTKDVLSVAFSADNRQIVSGSRDKTIKLWNTLAECK 636
>26939
          Length = 388

 Score =  106 bits (265), Expect = 1e-23,   Method: Compositional matrix adjust.
 Identities = 45/61 (73%), Positives = 55/61 (90%)
 Frame = +2

Query: 350 GKFILSCADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWEC 409
           GK+++S +DDKT+RVWD +NKRCMKTL AH+HF TS+DFHK  PYV++GSVDQTVKVWEC
Sbjct: 2   GKYLVSASDDKTIRVWDLRNKRCMKTLYAHQHFCTSIDFHKAHPYVISGSVDQTVKVWEC 181

Query: 410 R 410
           R
Sbjct: 182 R 184

 Score = 54.3 bits (129), Expect = 9e-08,   Method: Compositional matrix adjust.
 Identities = 22/61 (36%), Positives = 38/61 (62%)
 Frame = +2

Query: 162 GKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEV 221
           GK L S S D TI++WD +   C++T++ H H  +S+       +++S S D+T+K+WE 
Sbjct: 2   GKYLVSASDDKTIRVWDLRNKRCMKTLYAHQHFCTSIDFHKAHPYVISGSVDQTVKVWEC 181

Query: 222 Q 222
           +
Sbjct: 182 R 184

 Score = 53.9 bits (128), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 21/59 (35%), Positives = 38/59 (64%)
 Frame = +2

Query: 308 GPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWD 366
           G +L+S S DKTI++WD+    C+ TL  H ++   + FH    +++S + D+T++VW+
Sbjct: 2   GKYLVSASDDKTIRVWDLRNKRCMKTLYAHQHFCTSIDFHKAHPYVISGSVDQTVKVWE 178

 Score = 48.9 bits (115), Expect = 3e-06,   Method: Composition-based stats.
 Identities = 25/68 (36%), Positives = 41/68 (60%)
 Frame = +2

Query: 204 GDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVV 263
           G ++VSAS DKTI++W+++   C+KT   H+ +   +  ++    + S S DQTV+VW  
Sbjct: 2   GKYLVSASDDKTIRVWDLRNKRCMKTLYAHQHFCTSIDFHKAHPYVISGSVDQTVKVW-- 175

Query: 264 ATKECKAE 271
              EC+ E
Sbjct: 176 ---ECR*E 190

 Score = 44.3 bits (103), Expect = 8e-05,   Method: Compositional matrix adjust.
 Identities = 25/92 (27%), Positives = 41/92 (44%), Gaps = 5/92 (5%)
 Frame = +2

Query: 246 GTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSSISEATGSETKKSG 305
           G  + S S+D+T+RVW +  K C   L  H+H    I +                     
Sbjct: 2   GKYLVSASDDKTIRVWDLRNKRCMKTLYAHQHFCTSIDF--------------------H 121

Query: 306 KPGPFLLSGSRDKTIKMWDV-----STGMCLM 332
           K  P+++SGS D+T+K+W+      +  +CL 
Sbjct: 122 KAHPYVISGSVDQTVKVWECR*EHSANNICLF 217

 Score = 42.0 bits (97), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 21/56 (37%), Positives = 30/56 (53%)
 Frame = +2

Query: 123 MVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLWD 178
           +VSAS+D TI+VWD       +TL  H      I F  +   + S S D T+K+W+
Sbjct: 11  LVSASDDKTIRVWDLRNKRCMKTLYAHQHFCTSIDFHKAHPYVISGSVDQTVKVWE 178

 Score = 28.5 bits (62), Expect = 5.9,   Method: Compositional matrix adjust.
 Identities = 12/33 (36%), Positives = 18/33 (54%)
 Frame = +2

Query: 104 LSGHRSPVTRVIFHPVFSVMVSASEDATIKVWD 136
           L  H+   T + FH     ++S S D T+KVW+
Sbjct: 80  LYAHQHFCTSIDFHKAHPYVISGSVDQTVKVWE 178
>17598
          Length = 875

 Score = 97.4 bits (241), Expect = 8e-21,   Method: Compositional matrix adjust.
 Identities = 75/270 (27%), Positives = 118/270 (43%), Gaps = 14/270 (5%)
 Frame = +1

Query: 123 MVSASEDATIKVWDY---------ET-GDFERTLKGHTDSVQDISFDHSGKLLASCSADM 172
           ++    D  + VWD          ET G   RTL+GH+  V D+S     + + S S D 
Sbjct: 10  LIXGGRDKLLIVWDLVPRKDGDEDETWGGPRRTLQGHSHFVSDVSLSADSRYVLSSSWDA 189

Query: 173 TIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTF-- 230
           T++LWD +     R    H  +  +VA  P+   I S  RDK +K+W    G C  T   
Sbjct: 190 TLRLWDIKKGNTTRRFISHTRDALAVAFSPDNRQIASGGRDKALKIWNT-VGECKFTVDA 366

Query: 231 TGHREWVRMVRPNQDGT--LIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPES 288
             H++WV  V+ +QD    L+ S S D+T++VW   T   K     H+  +  I  A ++
Sbjct: 367 NSHQDWVTCVKFHQDAKSPLVVSASMDKTIKVWDNQTMTLKHTFVGHKTQINAIDLALKT 546

Query: 289 SYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHS 348
            Y                    L SGS+D  +  W++  G   +  +  D  V  V F S
Sbjct: 547 YY--------------------LASGSKDGIVMTWNIQNGT-FLGKIDCDCEVNAVKF-S 660

Query: 349 GGKFILSCADDKTLRVWDYKNKRCMKTLNA 378
             K+ L     + +++WD  N++ +K + A
Sbjct: 661 PNKYWLFVGTSEGIQIWDLPNQKKIKDIRA 750

 Score = 74.3 bits (181), Expect = 8e-14,   Method: Compositional matrix adjust.
 Identities = 51/167 (30%), Positives = 80/167 (47%), Gaps = 4/167 (2%)
 Frame = +1

Query: 101 KYALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDH 160
           +  L GH   V+ V        ++S+S DAT+++WD + G+  R    HT     ++F  
Sbjct: 100 RRTLQGHSHFVSDVSLSADSRYVLSSSWDATLRLWDIKKGNTTRRFISHTRDALAVAFSP 279

Query: 161 SGKLLASCSADMTIKLWDFQGFECIRTMHGHDHN--VSSVAIMPNGDH--IVSASRDKTI 216
             + +AS   D  +K+W+  G EC  T+  + H   V+ V    +     +VSAS DKTI
Sbjct: 280 DNRQIASGGRDKALKIWNTVG-ECKFTVDANSHQDWVTCVKFHQDAKSPLVVSASMDKTI 456

Query: 217 KMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVV 263
           K+W+ QT     TF GH+  +  +        +AS S D  V  W +
Sbjct: 457 KVWDNQTMTLKHTFVGHKTQINAIDLALKTYYLASGSKDGIVMTWNI 597

 Score = 71.6 bits (174), Expect = 5e-13,   Method: Compositional matrix adjust.
 Identities = 52/218 (23%), Positives = 91/218 (41%), Gaps = 14/218 (6%)
 Frame = +1

Query: 207 IVSASRDKTIKMWEVQT----------GYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQ 256
           ++   RDK + +W++            G   +T  GH  +V  V  + D   + S S D 
Sbjct: 10  LIXGGRDKLLIVWDLVPRKDGDEDETWGGPRRTLQGHSHFVSDVSLSADSRYVLSSSWDA 189

Query: 257 TVRVWVVATKECKAELREHEHVVECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSR 316
           T+R+W +           H      ++++P++                      + SG R
Sbjct: 190 TLRLWDIKKGNTTRRFISHTRDALAVAFSPDNRQ--------------------IASGGR 309

Query: 317 DKTIKMWDVSTGMCLMTLVG--HDNWVRGVLFHSGGK--FILSCADDKTLRVWDYKNKRC 372
           DK +K+W+ + G C  T+    H +WV  V FH   K   ++S + DKT++VWD +    
Sbjct: 310 DKALKIWN-TVGECKFTVDANSHQDWVTCVKFHQDAKSPLVVSASMDKTIKVWDNQTMTL 486

Query: 373 MKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWECR 410
             T   H+  + ++D      Y+ +GS D  V  W  +
Sbjct: 487 KHTFVGHKTQINAIDLALKTYYLASGSKDGIVMTWNIQ 600

 Score = 54.3 bits (129), Expect = 9e-08,   Method: Compositional matrix adjust.
 Identities = 32/115 (27%), Positives = 55/115 (47%), Gaps = 14/115 (12%)
 Frame = +1

Query: 310 FLLSGSRDKTIKMWDV----------STGMCLMTLVGHDNWVRGVLFHSGGKFILSCADD 359
           FL+ G RDK + +WD+          + G    TL GH ++V  V   +  +++LS + D
Sbjct: 7   FLIXGGRDKLLIVWDLVPRKDGDEDETWGGPRRTLQGHSHFVSDVSLSADSRYVLSSSWD 186

Query: 360 KTLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVW----ECR 410
            TLR+WD K     +   +H     ++ F      + +G  D+ +K+W    EC+
Sbjct: 187 ATLRLWDIKKGNTTRRFISHTRDALAVAFSPDNRQIASGGRDKALKIWNTVGECK 351

 Score = 46.2 bits (108), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 36/119 (30%), Positives = 56/119 (47%), Gaps = 2/119 (1%)
 Frame = +1

Query: 105 SGHRSPVTRVIFH--PVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSG 162
           + H+  VT V FH      ++VSAS D TIKVWD +T   + T  GH   +  I      
Sbjct: 367 NSHQDWVTCVKFHQDAKSPLVVSASMDKTIKVWDNQTMTLKHTFVGHKTQINAIDLALKT 546

Query: 163 KLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEV 221
             LAS S D  +  W+ Q    +  +   D  V++V   PN  + +     + I++W++
Sbjct: 547 YYLASGSKDGIVMTWNIQNGTFLGKIDC-DCEVNAVKFSPN-KYWLFVGTSEGIQIWDL 717
>12806
          Length = 961

 Score = 94.4 bits (233), Expect = 8e-20,   Method: Compositional matrix adjust.
 Identities = 70/273 (25%), Positives = 118/273 (43%), Gaps = 17/273 (6%)
 Frame = +3

Query: 123 MVSASEDATIKVWDY---ETGDFE-------RTLKGHTDSVQDISFDHSGKLLASCSADM 172
           ++S   D  I VWD    + GD +       +TL GH+  + D++     +   S S D 
Sbjct: 54  LISGGRDNNIIVWDL*PKKDGDEDQTWGVPRKTLTGHSHFISDLALSADSRFALSSSWDA 233

Query: 173 TIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTF-- 230
           T++LWD +          H  +V +VA  P+   I S  RDK +K+W +  G C  T   
Sbjct: 234 TLRLWDIKKGSTTSRFINHTRDVLTVAFSPDNRQIASGGRDKNLKIWNIM-GECKYTVDA 410

Query: 231 TGHREWVRMVRPNQD--GTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPES 288
             H +WV  VR +QD    ++ S SND+T++VW   T   K     H+  +  +  +   
Sbjct: 411 NAHTDWVTCVRFHQDTKNPIVVSASNDKTIKVWDNHTMTLKNTFVGHKAQITALDMSTN- 587

Query: 289 SYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLF-- 346
                                +L+SGS+D     W+V+ G   +  +  D+ +  + F  
Sbjct: 588 ---------------------YLVSGSKDGIAMTWNVAEG-SFVGKIDCDDQINAIKFNI 701

Query: 347 -HSGGKFILSCADDKTLRVWDYKNKRCMKTLNA 378
            ++  K  L       +++WDY  ++ +K L A
Sbjct: 702 ENNKKKVWLFIGTQNGIQIWDYSGEKKIKELKA 800

 Score = 79.3 bits (194), Expect = 2e-15,   Method: Compositional matrix adjust.
 Identities = 58/217 (26%), Positives = 96/217 (44%), Gaps = 14/217 (6%)
 Frame = +3

Query: 207 IVSASRDKTIKMWEV---------QT-GYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQ 256
           ++S  RD  I +W++         QT G   KT TGH  ++  +  + D     S S D 
Sbjct: 54  LISGGRDNNIIVWDL*PKKDGDEDQTWGVPRKTLTGHSHFISDLALSADSRFALSSSWDA 233

Query: 257 TVRVWVVATKECKAELREHEHVVECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSR 316
           T+R+W +      +    H   V  ++++P++                      + SG R
Sbjct: 234 TLRLWDIKKGSTTSRFINHTRDVLTVAFSPDNRQ--------------------IASGGR 353

Query: 317 DKTIKMWDVSTGMCLMTL--VGHDNWVRGVLFHSGGK--FILSCADDKTLRVWDYKNKRC 372
           DK +K+W++  G C  T+    H +WV  V FH   K   ++S ++DKT++VWD      
Sbjct: 354 DKNLKIWNI-MGECKYTVDANAHTDWVTCVRFHQDTKNPIVVSASNDKTIKVWDNHTMTL 530

Query: 373 MKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWEC 409
             T   H+  +T+LD   +  Y+V+GS D     W  
Sbjct: 531 KNTFVGHKAQITALDM--STNYLVSGSKDGIAMTWNV 635

 Score = 69.3 bits (168), Expect = 3e-12,   Method: Compositional matrix adjust.
 Identities = 50/174 (28%), Positives = 81/174 (46%), Gaps = 4/174 (2%)
 Frame = +3

Query: 95  IPRPPEKYALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQ 154
           +PR      L+GH   ++ +         +S+S DAT+++WD + G        HT  V 
Sbjct: 138 VPRK----TLTGHSHFISDLALSADSRFALSSSWDATLRLWDIKKGSTTSRFINHTRDVL 305

Query: 155 DISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHN--VSSVAIMPNGDH--IVSA 210
            ++F    + +AS   D  +K+W+  G EC  T+  + H   V+ V    +  +  +VSA
Sbjct: 306 TVAFSPDNRQIASGGRDKNLKIWNIMG-ECKYTVDANAHTDWVTCVRFHQDTKNPIVVSA 482

Query: 211 SRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVA 264
           S DKTIK+W+  T     TF GH+   ++   +     + S S D     W VA
Sbjct: 483 SNDKTIKVWDNHTMTLKNTFVGHK--AQITALDMSTNYLVSGSKDGIAMTWNVA 638

 Score = 61.2 bits (147), Expect = 8e-10,   Method: Compositional matrix adjust.
 Identities = 35/120 (29%), Positives = 56/120 (46%), Gaps = 14/120 (11%)
 Frame = +3

Query: 305 GKPGPFLLSGSRDKTIKMWDV----------STGMCLMTLVGHDNWVRGVLFHSGGKFIL 354
           G   PFL+SG RD  I +WD+          + G+   TL GH +++  +   +  +F L
Sbjct: 36  GATKPFLISGGRDNNIIVWDL*PKKDGDEDQTWGVPRKTLTGHSHFISDLALSADSRFAL 215

Query: 355 SCADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVW----ECR 410
           S + D TLR+WD K          H   V ++ F      + +G  D+ +K+W    EC+
Sbjct: 216 SSSWDATLRLWDIKKGSTTSRFINHTRDVLTVAFSPDNRQIASGGRDKNLKIWNIMGECK 395
>17602
          Length = 481

 Score = 90.5 bits (223), Expect = 1e-18,   Method: Compositional matrix adjust.
 Identities = 47/133 (35%), Positives = 72/133 (54%), Gaps = 4/133 (3%)
 Frame = +3

Query: 133 KVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHD 192
           ++WD +TG   +TL  H+D V  + F+  G L+ S S D   ++WD    +C+ T+   D
Sbjct: 3   RIWDVKTGKCLKTLPAHSDPVTAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLXTLIDDD 182

Query: 193 H-NVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPN---QDGTL 248
           +  VS V   PNG +I++A+ D T+K+W+   G C+KT+ GHR     +  N     G  
Sbjct: 183 NPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYVGHRNEKYCIFANFSVTGGKW 362

Query: 249 IASCSNDQTVRVW 261
           I S S D  V +W
Sbjct: 363 IVSGSEDNMVYIW 401

 Score = 85.5 bits (210), Expect = 3e-17,   Method: Compositional matrix adjust.
 Identities = 49/153 (32%), Positives = 80/153 (52%), Gaps = 3/153 (1%)
 Frame = +3

Query: 217 KMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHE 276
           ++W+V+TG C+KT   H + V  V  N+DG+LI S S D   R+W  A+ +C   L + +
Sbjct: 3   RIWDVKTGKCLKTLPAHSDPVTAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLXTLIDDD 182

Query: 277 HVVECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVG 336
           +        P  S+   S             G ++L+ + D T+K+WD S G CL T VG
Sbjct: 183 N--------PPVSFVKFSPN-----------GKYILAATLDNTLKLWDYSKGKCLKTYVG 305

Query: 337 HDNWVRGVLFH---SGGKFILSCADDKTLRVWD 366
           H N    +  +   +GGK+I+S ++D  + +W+
Sbjct: 306 HRNEKYCIFANFSVTGGKWIVSGSEDNMVYIWN 404

 Score = 75.1 bits (183), Expect = 5e-14,   Method: Compositional matrix adjust.
 Identities = 47/154 (30%), Positives = 71/154 (46%), Gaps = 4/154 (2%)
 Frame = +3

Query: 259 RVWVVATKECKAELREHEHVVECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDK 318
           R+W V T +C   L  H   V  + +                     + G  ++S S D 
Sbjct: 3   RIWDVKTGKCLKTLPAHSDPVTAVHF--------------------NRDGSLIVSSSYDG 122

Query: 319 TIKMWDVSTGMCLMTLVGHDNW-VRGVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTLN 377
             ++WD ++G CL TL+  DN  V  V F   GK+IL+   D TL++WDY   +C+KT  
Sbjct: 123 LCRIWDTASGQCLXTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYV 302

Query: 378 AH--EHFVTSLDFHKT-APYVVTGSVDQTVKVWE 408
            H  E +    +F  T   ++V+GS D  V +W 
Sbjct: 303 GHRNEKYCIFANFSVTGGKWIVSGSEDNMVYIWN 404

 Score = 64.3 bits (155), Expect = 8e-11,   Method: Compositional matrix adjust.
 Identities = 42/145 (28%), Positives = 69/145 (47%), Gaps = 5/145 (3%)
 Frame = +3

Query: 104 LSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTL-KGHTDSVQDISFDHSG 162
           L  H  PVT V F+   S++VS+S D   ++WD  +G    TL       V  + F  +G
Sbjct: 42  LPAHSDPVTAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLXTLIDDDNPPVSFVKFSPNG 221

Query: 163 KLLASCSADMTIKLWDFQGFECIRTMHGH---DHNVSSVAIMPNGDHIVSASRDKTIKMW 219
           K + + + D T+KLWD+   +C++T  GH    + + +   +  G  IVS S D  + +W
Sbjct: 222 KYILAATLDNTLKLWDYSKGKCLKTYVGHRNEKYCIFANFSVTGGKWIVSGSEDNMVYIW 401

Query: 220 E-VQTGYCVKTFTGHREWVRMVRPN 243
             +  G   +    HR    +  P+
Sbjct: 402 NLLDQGDSTEATGSHRRGAVLCLPS 476

 Score = 58.5 bits (140), Expect = 4e-09,   Method: Compositional matrix adjust.
 Identities = 37/152 (24%), Positives = 74/152 (48%), Gaps = 1/152 (0%)
 Frame = +3

Query: 175 KLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGH- 233
           ++WD +  +C++T+  H   V++V    +G  IVS+S D   ++W+  +G C+ T     
Sbjct: 3   RIWDVKTGKCLKTLPAHSDPVTAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLXTLIDDD 182

Query: 234 REWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSSI 293
              V  V+ + +G  I + + D T+++W  +  +C      H +   CI       +++ 
Sbjct: 183 NPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYVGHRNEKYCI-------FANF 341

Query: 294 SEATGSETKKSGKPGPFLLSGSRDKTIKMWDV 325
           S  TG         G +++SGS D  + +W++
Sbjct: 342 S-VTG---------GKWIVSGSEDNMVYIWNL 407
>13335
          Length = 863

 Score = 88.6 bits (218), Expect = 4e-18,   Method: Compositional matrix adjust.
 Identities = 60/232 (25%), Positives = 101/232 (43%), Gaps = 12/232 (5%)
 Frame = +1

Query: 189 HGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTL 248
           H    ++      P+  H+VS S D TI MWEV T   V+++ GH + V  +  + +G  
Sbjct: 52  HASKSSIRVCKFSPSSSHLVSGSDDDTICMWEVATQKLVRSYVGHEDSVMALAYSPNGHY 231

Query: 249 IASCSNDQTVRVWVVATKECK---AELREHEHVVECISWAPESSYSSISEATGSETKKSG 305
           + S S +  + VW  +   C+     +  H+  V C  ++P    +          + S 
Sbjct: 232 LVSGSPNGDLYVWDASFGHCRHLTLRVDAHDLGVTCCEFSPTFGTAC--------AENSS 387

Query: 306 KPGPFLLSGSRDKTIKMWDVS--------TGMCLMTLVGHDNWVRGVLFHSGGKFILSCA 357
                L +G +D  IK+W  S        T  C   L GH + V    F      + S +
Sbjct: 388 TCNLLLATGGKDNLIKLWTFSAQVGSPEVTLQCRDILSGHSDLVMACAFSPSSALLASGS 567

Query: 358 DDKTLRVWDYKNKRCMKTLNA-HEHFVTSLDFHKTAPYVVTGSVDQTVKVWE 408
            DK++R+WD      + ++ A H  FVT   F      + +GS+D+ +K+W+
Sbjct: 568 FDKSVRLWDSVKGVALFSIEACHSRFVTCCAFSIDGTLLASGSMDRIIKIWK 723

 Score = 66.6 bits (161), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 61/255 (23%), Positives = 100/255 (39%), Gaps = 30/255 (11%)
 Frame = +1

Query: 108 RSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLAS 167
           +S +    F P  S +VS S+D TI +W+  T    R+  GH DSV  +++  +G  L S
Sbjct: 61  KSSIRVCKFSPSSSHLVSGSDDDTICMWEVATQKLVRSYVGHEDSVMALAYSPNGHYLVS 240

Query: 168 CSADMTIKLWDFQGFEC---IRTMHGHDHNVSSVAIMPNGDH------------IVSASR 212
            S +  + +WD     C      +  HD  V+     P                + +  +
Sbjct: 241 GSPNGDLYVWDASFGHCRHLTLRVDAHDLGVTCCEFSPTFGTACAENSSTCNLLLATGGK 420

Query: 213 DKTIKMW--EVQTG------YCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVW--- 261
           D  IK+W    Q G       C    +GH + V     +    L+AS S D++VR+W   
Sbjct: 421 DNLIKLWTFSAQVGSPEVTLQCRDILSGHSDLVMACAFSPSSALLASGSFDKSVRLWDSV 600

Query: 262 ----VVATKECKAELREHEHVVECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRD 317
               + + + C      H   V C +++ +                    G  L SGS D
Sbjct: 601 KGVALFSIEAC------HSRFVTCCAFSID--------------------GTLLASGSMD 702

Query: 318 KTIKMWDVSTGMCLM 332
           + IK+W ++    +M
Sbjct: 703 RIIKIWKLTDTSSIM 747

 Score = 60.5 bits (145), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 48/180 (26%), Positives = 75/180 (41%), Gaps = 24/180 (13%)
 Frame = +1

Query: 106 GHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFER-TLK--GHTDSVQDISFDHS- 161
           GH   V  + + P    +VS S +  + VWD   G     TL+   H   V    F  + 
Sbjct: 181 GHEDSVMALAYSPNGHYLVSGSPNGDLYVWDASFGHCRHLTLRVDAHDLGVTCCEFSPTF 360

Query: 162 -----------GKLLASCSADMTIKLWDFQG--------FECIRTMHGHDHNVSSVAIMP 202
                        LLA+   D  IKLW F           +C   + GH   V + A  P
Sbjct: 361 GTACAENSSTCNLLLATGGKDNLIKLWTFSAQVGSPEVTLQCRDILSGHSDLVMACAFSP 540

Query: 203 NGDHIVSASRDKTIKMWEVQTGYCVKTFTG-HREWVRMVRPNQDGTLIASCSNDQTVRVW 261
           +   + S S DK++++W+   G  + +    H  +V     + DGTL+AS S D+ +++W
Sbjct: 541 SSALLASGSFDKSVRLWDSVKGVALFSIEACHSRFVTCCAFSIDGTLLASGSMDRIIKIW 720

 Score = 43.5 bits (101), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 26/75 (34%), Positives = 39/75 (52%), Gaps = 1/75 (1%)
 Frame = +1

Query: 104 LSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKG-HTDSVQDISFDHSG 162
           LSGH   V    F P  +++ S S D ++++WD   G    +++  H+  V   +F   G
Sbjct: 496 LSGHSDLVMACAFSPSSALLASGSFDKSVRLWDSVKGVALFSIEACHSRFVTCCAFSIDG 675

Query: 163 KLLASCSADMTIKLW 177
            LLAS S D  IK+W
Sbjct: 676 TLLASGSMDRIIKIW 720
>12574
          Length = 521

 Score = 84.0 bits (206), Expect = 1e-16,   Method: Compositional matrix adjust.
 Identities = 41/116 (35%), Positives = 63/116 (54%)
 Frame = +3

Query: 96  PRPPEKYALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQD 155
           P    K+ L+GH   ++ V F P    + S+S D  IK+W    G FE+T+ GH   + D
Sbjct: 150 PTYTLKFTLAGHTKALSAVKFSPNGDWLASSSADKLIKIWGAYDGKFEKTIAGHKLGLSD 329

Query: 156 ISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSAS 211
           +++    KLL S S D T+K+W+F   +C++T+ GH + V      P  + IVS S
Sbjct: 330 VAWSSDSKLLCSASDDKTLKIWEFSTGKCMKTLKGHSNYVFCCNFNPQSNLIVSGS 497

 Score = 78.6 bits (192), Expect = 4e-15,   Method: Compositional matrix adjust.
 Identities = 44/109 (40%), Positives = 59/109 (54%)
 Frame = +3

Query: 145 TLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNG 204
           TL GHT ++  + F  +G  LAS SAD  IK+W     +  +T+ GH   +S VA   + 
Sbjct: 171 TLAGHTKALSAVKFSPNGDWLASSSADKLIKIWGAYDGKFEKTIAGHKLGLSDVAWSSDS 350

Query: 205 DHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCS 253
             + SAS DKT+K+WE  TG C+KT  GH  +V     N    LI S S
Sbjct: 351 KLLCSASDDKTLKIWEFSTGKCMKTLKGHSNYVFCCNFNPQSNLIVSGS 497

 Score = 78.2 bits (191), Expect = 6e-15,   Method: Compositional matrix adjust.
 Identities = 37/103 (35%), Positives = 60/103 (58%)
 Frame = +3

Query: 187 TMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDG 246
           T+ GH   +S+V   PNGD + S+S DK IK+W    G   KT  GH+  +  V  + D 
Sbjct: 171 TLAGHTKALSAVKFSPNGDWLASSSADKLIKIWGAYDGKFEKTIAGHKLGLSDVAWSSDS 350

Query: 247 TLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESS 289
            L+ S S+D+T+++W  +T +C   L+ H + V C ++ P+S+
Sbjct: 351 KLLCSASDDKTLKIWEFSTGKCMKTLKGHSNYVFCCNFNPQSN 479

 Score = 70.9 bits (172), Expect = 9e-13,   Method: Compositional matrix adjust.
 Identities = 34/93 (36%), Positives = 54/93 (58%)
 Frame = +3

Query: 308 GPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDY 367
           G +L S S DK IK+W    G    T+ GH   +  V + S  K + S +DDKTL++W++
Sbjct: 222 GDWLASSSADKLIKIWGAYDGKFEKTIAGHKLGLSDVAWSSDSKLLCSASDDKTLKIWEF 401

Query: 368 KNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSV 400
              +CMKTL  H ++V   +F+  +  +V+GS+
Sbjct: 402 STGKCMKTLKGHSNYVFCCNFNPQSNLIVSGSL 500

 Score = 43.1 bits (100), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 20/77 (25%), Positives = 41/77 (53%)
 Frame = +3

Query: 332 MTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFHKT 391
            TL GH   +  V F   G ++ S + DK +++W   + +  KT+  H+  ++ + +   
Sbjct: 168 FTLAGHTKALSAVKFSPNGDWLASSSADKLIKIWGAYDGKFEKTIAGHKLGLSDVAWSSD 347

Query: 392 APYVVTGSVDQTVKVWE 408
           +  + + S D+T+K+WE
Sbjct: 348 SKLLCSASDDKTLKIWE 398
>01327
          Length = 2215

 Score = 83.6 bits (205), Expect = 1e-16,   Method: Compositional matrix adjust.
 Identities = 63/255 (24%), Positives = 106/255 (41%), Gaps = 10/255 (3%)
 Frame = +3

Query: 164 LLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQT 223
           L  S S D ++ L+D+Q         GHD  ++ V    + + + SASRDKTIKMW+   
Sbjct: 81  LCLSGSKDKSVVLYDYQNGRLEDRWTGHDREITKVCYGASCNGMFSASRDKTIKMWQRGN 260

Query: 224 GYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECIS 283
            + ++ F GH   V  +  N D TL+ S S D TVR+W V T  C  +    +++V  + 
Sbjct: 261 SHSIRDFIGHDMVVTAIHLNTDNTLLCSGSRDNTVRIWDVETGACLRQNNIPQNLVTDVK 440

Query: 284 WAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRG 343
           W P S                      ++    DK ++++D  T   + +          
Sbjct: 441 WLPGSH--------------------LIIQAGEDKEVRIYDSRTLGIVRSFTKKQYIQMS 560

Query: 344 VLFHSGGKFILSCAD-------DKTLRVWDYKNKRCMKTLNAHEHFVTSLDF---HKTAP 393
               + G+F L+C++       + TL  W   +         H   + +  F   ++   
Sbjct: 561 CDVTADGQFCLTCSNGFGGNGCEATL--WQLSDGSIQNEFKGHREAIEACLFLPSNQDMT 734

Query: 394 YVVTGSVDQTVKVWE 408
            + T S D +V+VW 
Sbjct: 735 LIATASRDCSVRVWN 779

 Score = 83.2 bits (204), Expect = 2e-16,   Method: Compositional matrix adjust.
 Identities = 57/233 (24%), Positives = 105/233 (45%), Gaps = 6/233 (2%)
 Frame = +3

Query: 105 SGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKL 164
           +GH   +T+V +    + M SAS D TIK+W        R   GH   V  I  +    L
Sbjct: 156 TGHDREITKVCYGASCNGMFSASRDKTIKMWQRGNSHSIRDFIGHDMVVTAIHLNTDNTL 335

Query: 165 LASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTG 224
           L S S D T+++WD +   C+R  +   + V+ V  +P    I+ A  DK +++++ +T 
Sbjct: 336 LCSGSRDNTVRIWDVETGACLRQNNIPQNLVTDVKWLPGSHLIIQAGEDKEVRIYDSRTL 515

Query: 225 YCVKTFTGHREWVRM-VRPNQDGTLIASCS-----NDQTVRVWVVATKECKAELREHEHV 278
             V++FT  +++++M      DG    +CS     N     +W ++    + E + H   
Sbjct: 516 GIVRSFT-KKQYIQMSCDVTADGQFCLTCSNGFGGNGCEATLWQLSDGSIQNEFKGHREA 692

Query: 279 VECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCL 331
           +E   + P                 S +    + + SRD ++++W++ T  C+
Sbjct: 693 IEACLFLP-----------------SNQDMTLIATASRDCSVRVWNMFTKECV 800

 Score = 77.0 bits (188), Expect = 1e-14,   Method: Compositional matrix adjust.
 Identities = 59/256 (23%), Positives = 108/256 (42%), Gaps = 4/256 (1%)
 Frame = +3

Query: 122 VMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQG 181
           + +S S+D ++ ++DY+ G  E    GH   +  + +  S   + S S D TIK+W    
Sbjct: 81  LCLSGSKDKSVVLYDYQNGRLEDRWTGHDREITKVCYGASCNGMFSASRDKTIKMWQRGN 260

Query: 182 FECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVR 241
              IR   GHD  V+++ +  +   + S SRD T+++W+V+TG C++     +  V  V+
Sbjct: 261 SHSIRDFIGHDMVVTAIHLNTDNTLLCSGSRDNTVRIWDVETGACLRQNNIPQNLVTDVK 440

Query: 242 PNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHV-VECISWAPESSYSSISEATGSE 300
                 LI     D+ VR++   T        + +++ + C   A      + S   G  
Sbjct: 441 WLPGSHLIIQAGEDKEVRIYDSRTLGIVRSFTKKQYIQMSCDVTADGQFCLTCSNGFGGN 620

Query: 301 TKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGK---FILSCA 357
             ++                 +W +S G       GH   +   LF    +    I + +
Sbjct: 621 GCEA----------------TLWQLSDGSIQNEFKGHREAIEACLFLPSNQDMTLIATAS 752

Query: 358 DDKTLRVWDYKNKRCM 373
            D ++RVW+   K C+
Sbjct: 753 RDCSVRVWNMFTKECV 800

 Score = 60.1 bits (144), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 34/123 (27%), Positives = 61/123 (49%)
 Frame = +3

Query: 286 PESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVL 345
           P      +S AT     +S +PG   LSGS+DK++ ++D   G       GHD  +  V 
Sbjct: 12  PRHVRDPVSIATLWSA*RSIQPG-LCLSGSKDKSVVLYDYQNGRLEDRWTGHDREITKVC 188

Query: 346 FHSGGKFILSCADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVK 405
           + +    + S + DKT+++W   N   ++    H+  VT++  +     + +GS D TV+
Sbjct: 189 YGASCNGMFSASRDKTIKMWQRGNSHSIRDFIGHDMVVTAIHLNTDNTLLCSGSRDNTVR 368

Query: 406 VWE 408
           +W+
Sbjct: 369 IWD 377

 Score = 59.7 bits (143), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 27/100 (27%), Positives = 52/100 (52%)
 Frame = +3

Query: 311 LLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNK 370
           + S SRDKTIKMW       +   +GHD  V  +  ++    + S + D T+R+WD +  
Sbjct: 210 MFSASRDKTIKMWQRGNSHSIRDFIGHDMVVTAIHLNTDNTLLCSGSRDNTVRIWDVETG 389

Query: 371 RCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWECR 410
            C++  N  ++ VT + +   +  ++    D+ V++++ R
Sbjct: 390 ACLRQNNIPQNLVTDVKWLPGSHLIIQAGEDKEVRIYDSR 509
>03156
          Length = 1014

 Score = 83.2 bits (204), Expect = 2e-16,   Method: Compositional matrix adjust.
 Identities = 57/233 (24%), Positives = 105/233 (45%), Gaps = 6/233 (2%)
 Frame = +1

Query: 105 SGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKL 164
           +GH   +T+V +    + M SAS D TIK+W        R   GH   V  I  +    L
Sbjct: 46  TGHDREITKVCYGASCNGMFSASRDKTIKMWQRGNSHSIRDFIGHDMVVTAIHLNTDNTL 225

Query: 165 LASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTG 224
           L S S D T+++WD +   C+R  +   + V+ V  +P    I+ A  DK +++++ +T 
Sbjct: 226 LCSGSRDNTVRIWDVETGACLRQNNIPQNLVTDVKWLPGSHLIIQAGEDKEVRIYDSRTL 405

Query: 225 YCVKTFTGHREWVRM-VRPNQDGTLIASCS-----NDQTVRVWVVATKECKAELREHEHV 278
             V++FT  +++++M      DG    +CS     N     +W ++    + E + H   
Sbjct: 406 GIVRSFT-KKQYIQMSCDVTADGQFCLTCSNGFGGNGCEATLWQLSDGSIQNEFKGHREA 582

Query: 279 VECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCL 331
           +E   + P                 S +    + + SRD ++++W++ T  C+
Sbjct: 583 IEACLFLP-----------------SNQDMTLIATASRDCSVRVWNMFTKECV 690

 Score = 77.4 bits (189), Expect = 1e-14,   Method: Compositional matrix adjust.
 Identities = 56/229 (24%), Positives = 95/229 (41%), Gaps = 10/229 (4%)
 Frame = +1

Query: 190 GHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLI 249
           GHD  ++ V    + + + SASRDKTIKMW+    + ++ F GH   V  +  N D TL+
Sbjct: 49  GHDREITKVCYGASCNGMFSASRDKTIKMWQRGNSHSIRDFIGHDMVVTAIHLNTDNTLL 228

Query: 250 ASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSSISEATGSETKKSGKPGP 309
            S S D TVR+W V T  C  +    +++V  + W P S                     
Sbjct: 229 CSGSRDNTVRIWDVETGACLRQNNIPQNLVTDVKWLPGSH-------------------- 348

Query: 310 FLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCAD-------DKTL 362
            ++    DK ++++D  T   + +              + G+F L+C++       + TL
Sbjct: 349 LIIQAGEDKEVRIYDSRTLGIVRSFTKKQYIQMSCDVTADGQFCLTCSNGFGGNGCEATL 528

Query: 363 RVWDYKNKRCMKTLNAHEHFVTSLDF---HKTAPYVVTGSVDQTVKVWE 408
             W   +         H   + +  F   ++    + T S D +V+VW 
Sbjct: 529 --WQLSDGSIQNEFKGHREAIEACLFLPSNQDMTLIATASRDCSVRVWN 669

 Score = 63.2 bits (152), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 54/238 (22%), Positives = 95/238 (39%), Gaps = 4/238 (1%)
 Frame = +1

Query: 140 GDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVA 199
           G  E    GH   +  + +  S   + S S D TIK+W       IR   GHD  V+++ 
Sbjct: 25  GRLEDRWTGHDREITKVCYGASCNGMFSASRDKTIKMWQRGNSHSIRDFIGHDMVVTAIH 204

Query: 200 IMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVR 259
           +  +   + S SRD T+++W+V+TG C++     +  V  V+      LI     D+ VR
Sbjct: 205 LNTDNTLLCSGSRDNTVRIWDVETGACLRQNNIPQNLVTDVKWLPGSHLIIQAGEDKEVR 384

Query: 260 VWVVATKECKAELREHEHV-VECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDK 318
           ++   T        + +++ + C   A      + S   G    ++              
Sbjct: 385 IYDSRTLGIVRSFTKKQYIQMSCDVTADGQFCLTCSNGFGGNGCEA-------------- 522

Query: 319 TIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGK---FILSCADDKTLRVWDYKNKRCM 373
              +W +S G       GH   +   LF    +    I + + D ++RVW+   K C+
Sbjct: 523 --TLWQLSDGSIQNEFKGHREAIEACLFLPSNQDMTLIATASRDCSVRVWNMFTKECV 690

 Score = 59.7 bits (143), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 27/100 (27%), Positives = 52/100 (52%)
 Frame = +1

Query: 311 LLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNK 370
           + S SRDKTIKMW       +   +GHD  V  +  ++    + S + D T+R+WD +  
Sbjct: 100 MFSASRDKTIKMWQRGNSHSIRDFIGHDMVVTAIHLNTDNTLLCSGSRDNTVRIWDVETG 279

Query: 371 RCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWECR 410
            C++  N  ++ VT + +   +  ++    D+ V++++ R
Sbjct: 280 ACLRQNNIPQNLVTDVKWLPGSHLIIQAGEDKEVRIYDSR 399

 Score = 55.1 bits (131), Expect = 5e-08,   Method: Compositional matrix adjust.
 Identities = 40/170 (23%), Positives = 69/170 (40%)
 Frame = +1

Query: 230 FTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESS 289
           +TGH   +  V        + S S D+T+++W         +   H+ VV  I    +++
Sbjct: 43  WTGHDREITKVCYGASCNGMFSASRDKTIKMWQRGNSHSIRDFIGHDMVVTAIHLNTDNT 222

Query: 290 YSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSG 349
                                L SGSRD T+++WDV TG CL       N V  V +  G
Sbjct: 223 --------------------LLCSGSRDNTVRIWDVETGACLRQNNIPQNLVTDVKWLPG 342

Query: 350 GKFILSCADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGS 399
              I+   +DK +R++D +    +++    ++   S D      + +T S
Sbjct: 343 SHLIIQAGEDKEVRIYDSRTLGIVRSFTKKQYIQMSCDVTADGQFCLTCS 492
>02147
          Length = 1547

 Score = 81.3 bits (199), Expect = 6e-16,   Method: Compositional matrix adjust.
 Identities = 66/249 (26%), Positives = 116/249 (46%), Gaps = 21/249 (8%)
 Frame = +2

Query: 138 ETGDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSS 197
           +TGD+  T +GH  +V   + +      A+ +AD + K+WD +  E ++T   H H V S
Sbjct: 137 DTGDWIGTFEGHKGAVWGATLNREATRAATGAADFSAKIWDAEKGEELQTF-SHKHIVKS 313

Query: 198 VAIMPNGDHIVSASRDKTIKMWE-VQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQ 256
           V    +G  +++ S +K +K+++ V T    K+F GH   ++      DG  I S S+D+
Sbjct: 314 VDFSHDGTALLTGSNEKLLKVFDLVNTDAEPKSFAGHTSNIKGALFLSDGKRIISASDDK 493

Query: 257 TVRVWVVATKECKAELREHEHVVECISWAPESSYSSISEA---------TGSETKKSGKP 307
           TVR+W + T +   +L   +     ++ +P+ +   ++ +         T  E KK    
Sbjct: 494 TVRLWSLETCQEVQQLT-FDTPPTSLTLSPDKNTIIVTHSQNIAFYQADTLREMKKFEAE 670

Query: 308 GP-----------FLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSC 356
            P           F ++G  D  +  +D  TG  + +  GH   V  V F   G+   S 
Sbjct: 671 APISSASLHQSERFFVAGGEDFKMYKFDYETGKEIESFKGHFGPVHCVRFSPDGELYASG 850

Query: 357 ADDKTLRVW 365
           ++D TLR+W
Sbjct: 851 SEDGTLRLW 877

 Score = 63.9 bits (154), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 57/281 (20%), Positives = 107/281 (38%), Gaps = 40/281 (14%)
 Frame = +2

Query: 88  KRDPKEWIPRPPEKYALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLK 147
           + D  +WI          GH+  V     +   +   + + D + K+WD E G+  +T  
Sbjct: 131 RGDTGDWIG------TFEGHKGAVWGATLNREATRAATGAADFSAKIWDAEKGEELQTFS 292

Query: 148 GHTDSVQDISFDHSGKLLASCSADMTIKLWDFQGFEC-IRTMHGHDHNVSSVAIMPNGDH 206
            H   V+ + F H G  L + S +  +K++D    +   ++  GH  N+     + +G  
Sbjct: 293 -HKHIVKSVDFSHDGTALLTGSNEKLLKVFDLVNTDAEPKSFAGHTSNIKGALFLSDGKR 469

Query: 207 IVSASRDKTIKMWEVQTGYCVKTFTG---------------------------HREWVRM 239
           I+SAS DKT+++W ++T   V+  T                              + +R 
Sbjct: 470 IISASDDKTVRLWSLETCQEVQQLTFDTPPTSLTLSPDKNTIIVTHSQNIAFYQADTLRE 649

Query: 240 VRPNQDGTLIASCSNDQTVRVWVVATKECKA------------ELREHEHVVECISWAPE 287
           ++  +    I+S S  Q+ R +V   ++ K               + H   V C+ ++P+
Sbjct: 650 MKKFEAEAPISSASLHQSERFFVAGGEDFKMYKFDYETGKEIESFKGHFGPVHCVRFSPD 829

Query: 288 SSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTG 328
                               G    SGS D T+++W  + G
Sbjct: 830 --------------------GELYASGSEDGTLRLWQTTIG 892

 Score = 39.7 bits (91), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 23/83 (27%), Positives = 42/83 (50%)
 Frame = +2

Query: 327 TGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTLNAHEHFVTSL 386
           TG  + T  GH   V G   +       + A D + ++WD +    ++T  +H+H V S+
Sbjct: 140 TGDWIGTFEGHKGAVWGATLNREATRAATGAADFSAKIWDAEKGEELQTF-SHKHIVKSV 316

Query: 387 DFHKTAPYVVTGSVDQTVKVWEC 409
           DF      ++TGS ++ +KV++ 
Sbjct: 317 DFSHDGTALLTGSNEKLLKVFDL 385
>27465
          Length = 658

 Score = 80.5 bits (197), Expect = 1e-15,   Method: Compositional matrix adjust.
 Identities = 43/121 (35%), Positives = 64/121 (52%), Gaps = 1/121 (0%)
 Frame = -1

Query: 144 RTLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIM-P 202
           + L+ H   + +++F+ SG    + S D T K+WD    E + T+ GH + V ++A   P
Sbjct: 379 KVLRAHILPLTNVAFNKSGSSFITGSYDRTCKIWDTASAEELHTLEGHRNVVYAIAFNNP 200

Query: 203 NGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWV 262
            GD +++ S DKT K+W    G C  T  GH   +  V  N   TLIA+ S D T R+W 
Sbjct: 199 FGDKVITGSFDKTCKLWSTADGKCYHTLRGHTAEIVCVSFNPSSTLIATGSMDTTCRLWD 20

Query: 263 V 263
           V
Sbjct: 19  V 17

 Score = 72.8 bits (177), Expect = 3e-13,   Method: Compositional matrix adjust.
 Identities = 50/196 (25%), Positives = 91/196 (46%), Gaps = 16/196 (8%)
 Frame = -1

Query: 43  LDKKYAGLLEKKWTSVIRLQ---------KKVMELESKLNEAKEEFTSGGPLGQKRDPKE 93
           L+ +  G+L+ K   ++ L+         +++ E E  +  +K+E         ++    
Sbjct: 583 LEYEQGGILKTKAIDLLDLKPETDADLVVQEIAEKEQLITPSKQEHVKNWCFACRK---- 416

Query: 94  WIPRPPEKY------ALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLK 147
              RP + +       L  H  P+T V F+   S  ++ S D T K+WD  + +   TL+
Sbjct: 415 --TRPKDDHHFYLFKVLRAHILPLTNVAFNKSGSSFITGSYDRTCKIWDTASAEELHTLE 242

Query: 148 GHTDSVQDISFDHS-GKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDH 206
           GH + V  I+F++  G  + + S D T KLW     +C  T+ GH   +  V+  P+   
Sbjct: 241 GHRNVVYAIAFNNPFGDKVITGSFDKTCKLWSTADGKCYHTLRGHTAEIVCVSFNPSSTL 62

Query: 207 IVSASRDKTIKMWEVQ 222
           I + S D T ++W+V+
Sbjct: 61  IATGSMDTTCRLWDVE 14

 Score = 69.3 bits (168), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 33/105 (31%), Positives = 60/105 (57%), Gaps = 1/105 (0%)
 Frame = -1

Query: 305 GKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSG-GKFILSCADDKTLR 363
            K G   ++GS D+T K+WD ++   L TL GH N V  + F++  G  +++ + DKT +
Sbjct: 334 NKSGSSFITGSYDRTCKIWDTASAEELHTLEGHRNVVYAIAFNNPFGDKVITGSFDKTCK 155

Query: 364 VWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWE 408
           +W   + +C  TL  H   +  + F+ ++  + TGS+D T ++W+
Sbjct: 154 LWSTADGKCYHTLRGHTAEIVCVSFNPSSTLIATGSMDTTCRLWD 20

 Score = 63.2 bits (152), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 53/213 (24%), Positives = 90/213 (42%), Gaps = 21/213 (9%)
 Frame = -1

Query: 134 VWDYETGDFERT-------LKGHTDS---VQDISFDHSGKLLASCSADMTIKLWDF---- 179
           + +YE G   +T       LK  TD+   VQ+I+     + L + S    +K W F    
Sbjct: 586 ILEYEQGGILKTKAIDLLDLKPETDADLVVQEIA---EKEQLITPSKQEHVKNWCFACRK 416

Query: 180 ------QGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGH 233
                   F   + +  H   +++VA   +G   ++ S D+T K+W+  +   + T  GH
Sbjct: 415 TRPKDDHHFYLFKVLRAHILPLTNVAFNKSGSSFITGSYDRTCKIWDTASAEELHTLEGH 236

Query: 234 REWVRMVRPNQD-GTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSS 292
           R  V  +  N   G  + + S D+T ++W  A  +C   LR H   + C+S+ P S+   
Sbjct: 235 RNVVYAIAFNNPFGDKVITGSFDKTCKLWSTADGKCYHTLRGHTAEIVCVSFNPSST--- 65

Query: 293 ISEATGSETKKSGKPGPFLLSGSRDKTIKMWDV 325
                             + +GS D T ++WDV
Sbjct: 64  -----------------LIATGSMDTTCRLWDV 17

 Score = 55.8 bits (133), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 39/142 (27%), Positives = 61/142 (42%)
 Frame = -1

Query: 225 YCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISW 284
           Y  K    H   +  V  N+ G+   + S D+T ++W  A+ E    L  H +VV  I++
Sbjct: 388 YLFKVLRAHILPLTNVAFNKSGSSFITGSYDRTCKIWDTASAEELHTLEGHRNVVYAIAF 209

Query: 285 APESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGV 344
                              +   G  +++GS DKT K+W  + G C  TL GH   +  V
Sbjct: 208 -------------------NNPFGDKVITGSFDKTCKLWSTADGKCYHTLRGHTAEIVCV 86

Query: 345 LFHSGGKFILSCADDKTLRVWD 366
            F+     I + + D T R+WD
Sbjct: 85  SFNPSSTLIATGSMDTTCRLWD 20

 Score = 42.0 bits (97), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 23/77 (29%), Positives = 41/77 (53%), Gaps = 3/77 (3%)
 Frame = -1

Query: 334 LVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAP 393
           L  H   +  V F+  G   ++ + D+T ++WD  +   + TL  H + V ++ F+   P
Sbjct: 373 LRAHILPLTNVAFNKSGSSFITGSYDRTCKIWDTASAEELHTLEGHRNVVYAIAFNN--P 200

Query: 394 Y---VVTGSVDQTVKVW 407
           +   V+TGS D+T K+W
Sbjct: 199 FGDKVITGSFDKTCKLW 149

 Score = 32.7 bits (73), Expect = 0.31,   Method: Compositional matrix adjust.
 Identities = 14/36 (38%), Positives = 23/36 (63%)
 Frame = -1

Query: 373 MKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWE 408
            K L AH   +T++ F+K+    +TGS D+T K+W+
Sbjct: 382 FKVLRAHILPLTNVAFNKSGSSFITGSYDRTCKIWD 275
>19949
          Length = 903

 Score = 77.0 bits (188), Expect = 1e-14,   Method: Compositional matrix adjust.
 Identities = 45/151 (29%), Positives = 74/151 (49%)
 Frame = +2

Query: 111 VTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSA 170
           V  + FHP  +   S S D  +K+WD        T KGHT  V  + F   G+ +AS S 
Sbjct: 2   VKSLDFHPYGAYTASGSMDCNVKLWDIRRKGCIYTYKGHTGCVCCLRFSPDGRWIASASE 181

Query: 171 DMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTF 230
           D  +KLWD    + +  +  H   V+++   P+   + S S D+T+K W+++T   + T 
Sbjct: 182 DGLVKLWDLTAGKLLTDLKLHRDAVNTIEFHPHEFLLASGSADRTVKFWDLETFQLISTT 361

Query: 231 TGHREWVRMVRPNQDGTLIASCSNDQTVRVW 261
                 +R +  + DG  + S S D T++V+
Sbjct: 362 EPEANSIRSILFHPDGVCLYSGSKD-TLKVY 451

 Score = 76.3 bits (186), Expect = 2e-14,   Method: Compositional matrix adjust.
 Identities = 44/118 (37%), Positives = 62/118 (52%)
 Frame = +2

Query: 102 YALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHS 161
           Y   GH   V  + F P    + SASED  +K+WD   G     LK H D+V  I F   
Sbjct: 101 YTYKGHTGCVCCLRFSPDGRWIASASEDGLVKLWDLTAGKLLTDLKLHRDAVNTIEFHPH 280

Query: 162 GKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMW 219
             LLAS SAD T+K WD + F+ I T     +++ S+   P+G  + S S+D T+K++
Sbjct: 281 EFLLASGSADRTVKFWDLETFQLISTTEPEANSIRSILFHPDGVCLYSGSKD-TLKVY 451

 Score = 71.6 bits (174), Expect = 5e-13,   Method: Compositional matrix adjust.
 Identities = 41/135 (30%), Positives = 65/135 (48%)
 Frame = +2

Query: 153 VQDISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASR 212
           V+ + F   G   AS S D  +KLWD +   CI T  GH   V  +   P+G  I SAS 
Sbjct: 2   VKSLDFHPYGAYTASGSMDCNVKLWDIRRKGCIYTYKGHTGCVCCLRFSPDGRWIASASE 181

Query: 213 DKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAEL 272
           D  +K+W++  G  +     HR+ V  +  +    L+AS S D+TV+ W + T +  +  
Sbjct: 182 DGLVKLWDLTAGKLLTDLKLHRDAVNTIEFHPHEFLLASGSADRTVKFWDLETFQLISTT 361

Query: 273 REHEHVVECISWAPE 287
               + +  I + P+
Sbjct: 362 EPEANSIRSILFHPD 406

 Score = 69.3 bits (168), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 32/101 (31%), Positives = 54/101 (53%)
 Frame = +2

Query: 308 GPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDY 367
           G +  SGS D  +K+WD+    C+ T  GH   V  + F   G++I S ++D  +++WD 
Sbjct: 29  GAYTASGSMDCNVKLWDIRRKGCIYTYKGHTGCVCCLRFSPDGRWIASASEDGLVKLWDL 208

Query: 368 KNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWE 408
              + +  L  H   V +++FH     + +GS D+TVK W+
Sbjct: 209 TAGKLLTDLKLHRDAVNTIEFHPHEFLLASGSADRTVKFWD 331

 Score = 63.5 bits (153), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 42/162 (25%), Positives = 73/162 (45%)
 Frame = +2

Query: 246 GTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSSISEATGSETKKSG 305
           G   AS S D  V++W +  K C    + H   V C+ ++P+                  
Sbjct: 29  GAYTASGSMDCNVKLWDIRRKGCIYTYKGHTGCVCCLRFSPD------------------ 154

Query: 306 KPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVW 365
             G ++ S S D  +K+WD++ G  L  L  H + V  + FH     + S + D+T++ W
Sbjct: 155 --GRWIASASEDGLVKLWDLTAGKLLTDLKLHRDAVNTIEFHPHEFLLASGSADRTVKFW 328

Query: 366 DYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVW 407
           D +  + + T     + + S+ FH     + +GS D T+KV+
Sbjct: 329 DLETFQLISTTEPEANSIRSILFHPDGVCLYSGSKD-TLKVY 451

 Score = 42.7 bits (99), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 20/68 (29%), Positives = 34/68 (50%)
 Frame = +2

Query: 341 VRGVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSV 400
           V+ + FH  G +  S + D  +++WD + K C+ T   H   V  L F     ++ + S 
Sbjct: 2   VKSLDFHPYGAYTASGSMDCNVKLWDIRRKGCIYTYKGHTGCVCCLRFSPDGRWIASASE 181

Query: 401 DQTVKVWE 408
           D  VK+W+
Sbjct: 182 DGLVKLWD 205

 Score = 33.9 bits (76), Expect = 0.11,   Method: Compositional matrix adjust.
 Identities = 14/28 (50%), Positives = 18/28 (64%)
 Frame = +2

Query: 383 VTSLDFHKTAPYVVTGSVDQTVKVWECR 410
           V SLDFH    Y  +GS+D  VK+W+ R
Sbjct: 2   VKSLDFHPYGAYTASGSMDCNVKLWDIR 85
>02960
          Length = 1577

 Score = 67.8 bits (164), Expect = 9e-12,   Method: Compositional matrix adjust.
 Identities = 78/325 (24%), Positives = 141/325 (43%), Gaps = 42/325 (12%)
 Frame = +2

Query: 124 VSASEDATIKVWDYETGDFERTLKGHTDSVQDISF---DHSGKL--LASCSADMTIKLWD 178
           +S S D T+++W  + G+   T+ GHT  V+ +++   D S  +    + S D T  +W 
Sbjct: 527 LSGSYDNTVRLWSTK-GEAIMTIPGHTSPVKCVAWIKHDESSGVSTFVTGSHDQTALVWQ 703

Query: 179 FQ----GFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWE-------------- 220
           +Q      +C  +  GH  +V  VA+ P+   + + S DK +K+W               
Sbjct: 704 WQRETNEVDCRLSCRGHAASVDCVAVSPDSQQMCTGSWDKMLKLWSTDCNVDGDQSEDTE 883

Query: 221 ------------VQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKEC 268
                        QT   V T +GH E V  VR   D   + + S D ++R+W + T + 
Sbjct: 884 RPSKKKKSAKSTTQTRVPVLTLSGHAEAVSAVR-WLDPHRVVTSSWDHSLRLWDLHTAQQ 1060

Query: 269 KAELREHEHVVECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDV--- 325
            + ++  + V++        +YS +S                L++GS D+ +++ D    
Sbjct: 1061TSLIQGSKAVLDV-------AYSPLSH--------------MLITGSADRHVRLVDPRCS 1177

Query: 326 --STGMCLMTLVGHDNWVRGVLFHSGGK-FILSCADDKTLRVWDYKN-KRCMKTLNAHEH 381
              T  C  T   H  WV GV +    +   LS + D  L++WD ++ K  +  +N HE 
Sbjct: 1178EGETVKCAFT--SHTGWVTGVDWSPTREHLFLSGSYDNVLKLWDTRSPKATLYDMNWHED 1351

Query: 382 FVTSLDFHKTAPYVVTGSVDQTVKV 406
            + ++D+      +++G VD  + V
Sbjct: 1352RILAVDW-SIPELLLSGGVDNKLHV 1423

 Score = 41.6 bits (96), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 55/222 (24%), Positives = 94/222 (42%), Gaps = 35/222 (15%)
 Frame = +2

Query: 101 KYALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDY-------ETGDFER--------- 144
           + +  GH + V  V   P    M + S D  +K+W         ++ D ER         
Sbjct: 734 RLSCRGHAASVDCVAVSPDSQQMCTGSWDKMLKLWSTDCNVDGDQSEDTERPSKKKKSAK 913

Query: 145 ----------TLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHN 194
                     TL GH ++V  + +    +++ S S D +++LWD    +    + G    
Sbjct: 914 STTQTRVPVLTLSGHAEAVSAVRWLDPHRVVTS-SWDHSLRLWDLHTAQQTSLIQG-SKA 1087

Query: 195 VSSVAIMPNGDHIVSASRDKTIKMWEVQT--GYCVK-TFTGHREWVRMV--RPNQDGTLI 249
           V  VA  P    +++ S D+ +++ + +   G  VK  FT H  WV  V   P ++  L 
Sbjct: 1088VLDVAYSPLSHMLITGSADRHVRLVDPRCSEGETVKCAFTSHTGWVTGVDWSPTREH-LF 1264

Query: 250 ASCSNDQTVRVWVVATKECKAELRE---HEHVVECISWA-PE 287
            S S D  +++W   T+  KA L +   HE  +  + W+ PE
Sbjct: 1265LSGSYDNVLKLW--DTRSPKATLYDMNWHEDRILAVDWSIPE 1384
>21105
          Length = 650

 Score = 62.4 bits (150), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 33/107 (30%), Positives = 53/107 (49%), Gaps = 4/107 (3%)
 Frame = +1

Query: 117 HPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIKL 176
           HP   + ++A ED  I+ +D  TG     +  H DSV  ++ D +G  L S S D +I+L
Sbjct: 91  HPTMPITITAHEDRHIRFFDNNTGKLIHAMVAHLDSVTSLAVDPNGLYLLSGSHDCSIRL 270

Query: 177 WDFQGFECIRTMHGH----DHNVSSVAIMPNGDHIVSASRDKTIKMW 219
           W+     C++ +  H    D ++  VA  P   +I SA  D   K++
Sbjct: 271 WNLDSKTCVQEITSHRKKFDESIHDVAFHPQKPYIASAGADALAKVF 411

 Score = 56.2 bits (134), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 25/103 (24%), Positives = 53/103 (51%), Gaps = 4/103 (3%)
 Frame = +1

Query: 309 PFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYK 368
           P  ++   D+ I+ +D +TG  +  +V H + V  +     G ++LS + D ++R+W+  
Sbjct: 103 PITITAHEDRHIRFFDNNTGKLIHAMVAHLDSVTSLAVDPNGLYLLSGSHDCSIRLWNLD 282

Query: 369 NKRCMKTLNAH----EHFVTSLDFHKTAPYVVTGSVDQTVKVW 407
           +K C++ + +H    +  +  + FH   PY+ +   D   KV+
Sbjct: 283 SKTCVQEITSHRKKFDESIHDVAFHPQKPYIASAGADALAKVF 411

 Score = 52.8 bits (125), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 30/96 (31%), Positives = 50/96 (52%), Gaps = 4/96 (4%)
 Frame = +1

Query: 171 DMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTF 230
           D  I+ +D    + I  M  H  +V+S+A+ PNG +++S S D +I++W + +  CV+  
Sbjct: 127 DRHIRFFDNNTGKLIHAMVAHLDSVTSLAVDPNGLYLLSGSHDCSIRLWNLDSKTCVQEI 306

Query: 231 TGHR----EWVRMVRPNQDGTLIASCSNDQTVRVWV 262
           T HR    E +  V  +     IAS   D   +V+V
Sbjct: 307 TSHRKKFDESIHDVAFHPQKPYIASAGADALAKVFV 414

 Score = 42.0 bits (97), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 19/87 (21%), Positives = 44/87 (50%), Gaps = 4/87 (4%)
 Frame = +1

Query: 208 VSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKE 267
           ++A  D+ I+ ++  TG  +     H + V  +  + +G  + S S+D ++R+W + +K 
Sbjct: 112 ITAHEDRHIRFFDNNTGKLIHAMVAHLDSVTSLAVDPNGLYLLSGSHDCSIRLWNLDSKT 291

Query: 268 CKAELREH----EHVVECISWAPESSY 290
           C  E+  H    +  +  +++ P+  Y
Sbjct: 292 CVQEITSHRKKFDESIHDVAFHPQKPY 372

 Score = 40.4 bits (93), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 19/62 (30%), Positives = 32/62 (51%), Gaps = 4/62 (6%)
 Frame = +1

Query: 308 GPFLLSGSRDKTIKMWDVSTGMCLMTLVGH----DNWVRGVLFHSGGKFILSCADDKTLR 363
           G +LLSGS D +I++W++ +  C+  +  H    D  +  V FH    +I S   D   +
Sbjct: 226 GLYLLSGSHDCSIRLWNLDSKTCVQEITSHRKKFDESIHDVAFHPQKPYIASAGADALAK 405

Query: 364 VW 365
           V+
Sbjct: 406 VF 411
>12960
          Length = 550

 Score = 61.2 bits (147), Expect = 8e-10,   Method: Compositional matrix adjust.
 Identities = 34/119 (28%), Positives = 59/119 (49%)
 Frame = +2

Query: 143 ERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMP 202
           E T+     +V+ + F    +   +C +D ++KLW+      ++T  GH H V       
Sbjct: 152 EVTINCKQQAVRAVRFSVDSRYCMTCGSDKSVKLWNPHRELFLKTYIGHGHEVLDAQGSG 331

Query: 203 NGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVW 261
           +   I S   DKT+ +++V +G  ++ +  H   V  V+ N++ T+I S S D TVR W
Sbjct: 332 DNSQICSGGIDKTVVLFDVASGQALRKYRDHAGTVNCVKFNEESTVILSGSLDNTVRAW 508

 Score = 51.6 bits (122), Expect = 5e-07,   Method: Compositional matrix adjust.
 Identities = 34/138 (24%), Positives = 62/138 (44%)
 Frame = +2

Query: 187 TMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDG 246
           T++     V +V    +  + ++   DK++K+W       +KT+ GH   V   + + D 
Sbjct: 158 TINCKQQAVRAVRFSVDSRYCMTCGSDKSVKLWNPHRELFLKTYIGHGHEVLDAQGSGDN 337

Query: 247 TLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSSISEATGSETKKSGK 306
           + I S   D+TV ++ VA+ +   + R+H   V C+ +  ES+                 
Sbjct: 338 SQICSGGIDKTVVLFDVASGQALRKYRDHAGTVNCVKFNEEST----------------- 466

Query: 307 PGPFLLSGSRDKTIKMWD 324
               +LSGS D T++ WD
Sbjct: 467 ---VILSGSLDNTVRAWD 511

 Score = 50.1 bits (118), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 25/101 (24%), Positives = 52/101 (51%)
 Frame = +2

Query: 310 FLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKN 369
           + ++   DK++K+W+    + L T +GH + V           I S   DKT+ ++D  +
Sbjct: 215 YCMTCGSDKSVKLWNPHRELFLKTYIGHGHEVLDAQGSGDNSQICSGGIDKTVVLFDVAS 394

Query: 370 KRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWECR 410
            + ++    H   V  + F++ +  +++GS+D TV+ W+ R
Sbjct: 395 GQALRKYRDHAGTVNCVKFNEESTVILSGSLDNTVRAWDTR 517

 Score = 44.7 bits (104), Expect = 7e-05,   Method: Compositional matrix adjust.
 Identities = 36/142 (25%), Positives = 60/142 (42%)
 Frame = +2

Query: 229 TFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPES 288
           T    ++ VR VR + D     +C +D++V++W    +        H H           
Sbjct: 158 TINCKQQAVRAVRFSVDSRYCMTCGSDKSVKLWNPHRELFLKTYIGHGH----------- 304

Query: 289 SYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHS 348
               + +A GS           + SG  DKT+ ++DV++G  L     H   V  V F+ 
Sbjct: 305 ---EVLDAQGSGDNSQ------ICSGGIDKTVVLFDVASGQALRKYRDHAGTVNCVKFNE 457

Query: 349 GGKFILSCADDKTLRVWDYKNK 370
               ILS + D T+R WD +++
Sbjct: 458 ESTVILSGSLDNTVRAWDTRSR 523

 Score = 38.5 bits (88), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 17/68 (25%), Positives = 35/68 (51%)
 Frame = +2

Query: 341 VRGVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSV 400
           VR V F    ++ ++C  DK++++W+   +  +KT   H H V           + +G +
Sbjct: 182 VRAVRFSVDSRYCMTCGSDKSVKLWNPHRELFLKTYIGHGHEVLDAQGSGDNSQICSGGI 361

Query: 401 DQTVKVWE 408
           D+TV +++
Sbjct: 362 DKTVVLFD 385
>13278
          Length = 870

 Score = 60.8 bits (146), Expect = 9e-10,   Method: Compositional matrix adjust.
 Identities = 34/97 (35%), Positives = 54/97 (55%)
 Frame = +1

Query: 164 LLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQT 223
           +LAS S D T++LW+ +   C+ T+  H   V SVA  P+G ++ S S DK + +W VQT
Sbjct: 118 ILASASFDSTVRLWEVERGLCLHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNVQT 297

Query: 224 GYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRV 260
           G  V ++ G    +  V  N  G  + + ++D +V V
Sbjct: 298 GSLVHSYKGTGG-IFEVCWNHRGDKVGASASDGSVFV 405

 Score = 53.1 bits (126), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 29/65 (44%), Positives = 40/65 (61%), Gaps = 1/65 (1%)
 Frame = +1

Query: 202 PNGDHIV-SASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRV 260
           PN   I+ SAS D T+++WEV+ G C+ T T H+E V  V  + DG  +AS S D+ V +
Sbjct: 103 PNTSLILASASFDSTVRLWEVERGLCLHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHI 282

Query: 261 WVVAT 265
           W V T
Sbjct: 283 WNVQT 297

 Score = 51.2 bits (121), Expect = 7e-07,   Method: Compositional matrix adjust.
 Identities = 31/109 (28%), Positives = 49/109 (44%)
 Frame = +1

Query: 260 VWVVATKECKAELREHEHVVECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKT 319
           +W +    C  +L+     +  I W+P          TG  T         L S S D T
Sbjct: 1   IWSMGKDSCIHDLQLTTKEIYTIKWSP----------TGPGTSNPNT-SLILASASFDST 147

Query: 320 IKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYK 368
           +++W+V  G+CL TL  H   V  V F   GK++ S + DK + +W+ +
Sbjct: 148 VRLWEVERGLCLHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNVQ 294

 Score = 49.7 bits (117), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 34/124 (27%), Positives = 58/124 (46%)
 Frame = +1

Query: 93  EWIPRPPEKYALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDS 152
           +W P  P      G  +P T +I       + SAS D+T+++W+ E G    TL  H + 
Sbjct: 70  KWSPTGP------GTSNPNTSLI-------LASASFDSTVRLWEVERGLCLHTLTKHQEP 210

Query: 153 VQDISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASR 212
           V  ++F   GK LAS S D  + +W+ Q    + +  G    +  V     GD + +++ 
Sbjct: 211 VYSVAFSPDGKYLASGSFDKCVHIWNVQTGSLVHSYKGTG-GIFEVCWNHRGDKVGASAS 387

Query: 213 DKTI 216
           D ++
Sbjct: 388 DGSV 399

 Score = 44.3 bits (103), Expect = 9e-05,   Method: Compositional matrix adjust.
 Identities = 35/128 (27%), Positives = 56/128 (43%)
 Frame = +1

Query: 241 RPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSSISEATGSE 300
            PN    ++AS S D TVR+W V    C   L +H+  V  ++++P+             
Sbjct: 100 NPNTS-LILASASFDSTVRLWEVERGLCLHTLTKHQEPVYSVAFSPD------------- 237

Query: 301 TKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDK 360
                  G +L SGS DK + +W+V TG  + +  G          H G K + + A D 
Sbjct: 238 -------GKYLASGSFDKCVHIWNVQTGSLVHSYKGTGGIFEVCWNHRGDK-VGASASDG 393

Query: 361 TLRVWDYK 368
           ++ V D +
Sbjct: 394 SVFVLDLR 417

 Score = 42.7 bits (99), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 20/79 (25%), Positives = 42/79 (53%)
 Frame = +1

Query: 102 YALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHS 161
           + L+ H+ PV  V F P    + S S D  + +W+ +TG    + KG T  + ++ ++H 
Sbjct: 184 HTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNVQTGSLVHSYKG-TGGIFEVCWNHR 360

Query: 162 GKLLASCSADMTIKLWDFQ 180
           G  + + ++D ++ + D +
Sbjct: 361 GDKVGASASDGSVFVLDLR 417
>18981
          Length = 407

 Score = 60.5 bits (145), Expect = 1e-09,   Method: Composition-based stats.
 Identities = 38/125 (30%), Positives = 64/125 (51%), Gaps = 1/125 (0%)
 Frame = -2

Query: 164 LLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQT 223
           ++ S + D T+++W  +    + T+ GH+ +V  V I   G  +VS S DKT+ +WEV T
Sbjct: 382 MIISAATDRTLRVWCLKNTCLLHTLRGHNDDVECVCIY--GRRVVSGSWDKTLIVWEVDT 209

Query: 224 GYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHV-VECI 282
           G  V    GH E +  V+ ++   +  S S D  VR W + T +C   +   + + V C+
Sbjct: 208 GRPVHQLHGHTEAITAVQFDEGKAV--SGSADGDVRTWALDTGQCLLTMTTGQDIEVYCV 35

Query: 283 SWAPE 287
            +  E
Sbjct: 34  VYNQE 20

 Score = 58.9 bits (141), Expect = 4e-09,   Method: Composition-based stats.
 Identities = 33/115 (28%), Positives = 60/115 (52%)
 Frame = -2

Query: 117 HPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIKL 176
           H + ++++SA+ D T++VW  +      TL+GH D V+ +     G+ + S S D T+ +
Sbjct: 397 HLLDNMIISAATDRTLRVWCLKNTCLLHTLRGHNDDVECVCI--YGRRVVSGSWDKTLIV 224

Query: 177 WDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFT 231
           W+      +  +HGH   +++V    +    VS S D  ++ W + TG C+ T T
Sbjct: 223 WEVDTGRPVHQLHGHTEAITAVQF--DEGKAVSGSADGDVRTWALDTGQCLLTMT 65

 Score = 52.0 bits (123), Expect = 4e-07,   Method: Composition-based stats.
 Identities = 30/97 (30%), Positives = 54/97 (55%)
 Frame = -2

Query: 311 LLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNK 370
           ++S + D+T+++W +     L TL GH++ V  V  +  G+ ++S + DKTL VW+    
Sbjct: 379 IISAATDRTLRVWCLKNTCLLHTLRGHNDDVECVCIY--GRRVVSGSWDKTLIVWEVDTG 206

Query: 371 RCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVW 407
           R +  L+ H   +T++ F +     V+GS D  V+ W
Sbjct: 205 RPVHQLHGHTEAITAVQFDEGK--AVSGSADGDVRTW 101

 Score = 49.3 bits (116), Expect = 3e-06,   Method: Composition-based stats.
 Identities = 36/129 (27%), Positives = 55/129 (42%)
 Frame = -2

Query: 248 LIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSSISEATGSETKKSGKP 307
           +I S + D+T+RVW +        LR H   VEC+                         
Sbjct: 382 MIISAATDRTLRVWCLKNTCLLHTLRGHNDDVECVCIY---------------------- 269

Query: 308 GPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDY 367
           G  ++SGS DKT+ +W+V TG  +  L GH   +  V F  G    +S + D  +R W  
Sbjct: 268 GRRVVSGSWDKTLIVWEVDTGRPVHQLHGHTEAITAVQFDEGKA--VSGSADGDVRTWAL 95

Query: 368 KNKRCMKTL 376
              +C+ T+
Sbjct: 94  DTGQCLLTM 68

 Score = 44.7 bits (104), Expect = 6e-05,   Method: Composition-based stats.
 Identities = 34/98 (34%), Positives = 49/98 (50%), Gaps = 1/98 (1%)
 Frame = -2

Query: 102 YALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHS 161
           + L GH   V  V  +     +VS S D T+ VW+ +TG     L GHT+++  + FD  
Sbjct: 316 HTLRGHNDDVECVCIYG--RRVVSGSWDKTLIVWEVDTGRPVHQLHGHTEAITAVQFDE- 146

Query: 162 GKLLASCSADMTIKLWDFQGFECIRTM-HGHDHNVSSV 198
           GK + S SAD  ++ W     +C+ TM  G D  V  V
Sbjct: 145 GKAV-SGSADGDVRTWALDTGQCLLTMTTGQDIEVYCV 35

 Score = 40.8 bits (94), Expect = 0.001,   Method: Composition-based stats.
 Identities = 24/56 (42%), Positives = 32/56 (57%)
 Frame = -2

Query: 353 ILSCADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWE 408
           I+S A D+TLRVW  KN   + TL  H   V  +  +     VV+GS D+T+ VWE
Sbjct: 379 IISAATDRTLRVWCLKNTCLLHTLRGHNDDVECVCIY--GRRVVSGSWDKTLIVWE 218
>31474
          Length = 403

 Score = 57.8 bits (138), Expect = 8e-09,   Method: Compositional matrix adjust.
 Identities = 39/129 (30%), Positives = 65/129 (50%), Gaps = 5/129 (3%)
 Frame = -3

Query: 76  KEEFTSGGPLGQKRDPKEWIPRPPEKYALSGHRSPVTRVIFHPVFSVMVSASEDATIKVW 135
           +++ TSG    ++   K  +    E   LS H      V ++P  +++ S   D  IK+W
Sbjct: 401 EQKATSGVVHFRRTHAKMAMATLEEVCCLSAHDEHAWCVAWNPTGTLLASCGSDKIIKIW 222

Query: 136 DYETGDF--ERTLK-GHTDSVQDISFDHSGKLLASCSADMTIKLWDFQG--FECIRTMHG 190
             E  ++  + TL   HT +V+ + +   G  L+S S D T  +W  +G  FECI T+ G
Sbjct: 221 GKEGDNWVCKSTLTDAHTRTVRSLGWSPCGNYLSSASFDATTAVWSRKGGEFECIATLEG 42

Query: 191 HDHNVSSVA 199
           H++ V +VA
Sbjct: 41  HENEVKAVA 15

 Score = 55.1 bits (131), Expect = 6e-08,   Method: Compositional matrix adjust.
 Identities = 33/100 (33%), Positives = 52/100 (52%), Gaps = 5/100 (5%)
 Frame = -3

Query: 146 LKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQG--FECIRTM-HGHDHNVSSVAIMP 202
           L  H +    ++++ +G LLASC +D  IK+W  +G  + C  T+   H   V S+   P
Sbjct: 317 LSAHDEHAWCVAWNPTGTLLASCGSDKIIKIWGKEGDNWVCKSTLTDAHTRTVRSLGWSP 138

Query: 203 NGDHIVSASRDKTIKMWEVQTG--YCVKTFTGHREWVRMV 240
            G+++ SAS D T  +W  + G   C+ T  GH   V+ V
Sbjct: 137 CGNYLSSASFDATTAVWSRKGGEFECIATLEGHENEVKAV 18

 Score = 46.6 bits (109), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 38/128 (29%), Positives = 55/128 (42%), Gaps = 8/128 (6%)
 Frame = -3

Query: 227 VKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKE-----CKAELRE-HEHVVE 280
           V   + H E    V  N  GTL+ASC +D+ +++W    KE     CK+ L + H   V 
Sbjct: 326 VCCLSAHDEHAWCVAWNPTGTLLASCGSDKIIKIW---GKEGDNWVCKSTLTDAHTRTVR 156

Query: 281 CISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTG--MCLMTLVGHD 338
            + W+P                     G +L S S D T  +W    G   C+ TL GH+
Sbjct: 155 SLGWSP--------------------CGNYLSSASFDATTAVWSRKGGEFECIATLEGHE 36

Query: 339 NWVRGVLF 346
           N V+ V +
Sbjct: 35  NEVKAVAW 12

 Score = 46.6 bits (109), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 36/109 (33%), Positives = 49/109 (44%), Gaps = 5/109 (4%)
 Frame = -3

Query: 182 FECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMW--EVQTGYCVKTFT-GHREWVR 238
            E +  +  HD +   VA  P G  + S   DK IK+W  E     C  T T  H   VR
Sbjct: 335 LEEVCCLSAHDEHAWCVAWNPTGTLLASCGSDKIIKIWGKEGDNWVCKSTLTDAHTRTVR 156

Query: 239 MVRPNQDGTLIASCSNDQTVRVWVVATKE--CKAELREHEHVVECISWA 285
            +  +  G  ++S S D T  VW     E  C A L  HE+ V+ ++WA
Sbjct: 155 SLGWSPCGNYLSSASFDATTAVWSRKGGEFECIATLEGHENEVKAVAWA 9

 Score = 41.6 bits (96), Expect = 6e-04,   Method: Compositional matrix adjust.
 Identities = 25/80 (31%), Positives = 37/80 (46%), Gaps = 3/80 (3%)
 Frame = -3

Query: 331 LMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVW--DYKNKRCMKTL-NAHEHFVTSLD 387
           +  L  HD     V ++  G  + SC  DK +++W  +  N  C  TL +AH   V SL 
Sbjct: 326 VCCLSAHDEHAWCVAWNPTGTLLASCGSDKIIKIWGKEGDNWVCKSTLTDAHTRTVRSLG 147

Query: 388 FHKTAPYVVTGSVDQTVKVW 407
           +     Y+ + S D T  VW
Sbjct: 146 WSPCGNYLSSASFDATTAVW 87

 Score = 36.2 bits (82), Expect = 0.027,   Method: Compositional matrix adjust.
 Identities = 19/55 (34%), Positives = 31/55 (56%), Gaps = 2/55 (3%)
 Frame = -3

Query: 106 GHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFE--RTLKGHTDSVQDISF 158
            H   V  + + P  + + SAS DAT  VW  + G+FE   TL+GH + V+ +++
Sbjct: 176 AHTRTVRSLGWSPCGNYLSSASFDATTAVWSRKGGEFECIATLEGHENEVKAVAW 12
>01805
          Length = 2124

 Score = 57.8 bits (138), Expect = 8e-09,   Method: Compositional matrix adjust.
 Identities = 46/191 (24%), Positives = 86/191 (45%), Gaps = 8/191 (4%)
 Frame = -1

Query: 228 KTFTGHREWVRMVRPNQDGT-LIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAP 286
           ++ TGH + V  +  N++   ++AS S D TV +W ++  +      +H   V+C +W P
Sbjct: 594 ESVTGHTQAVLDLSWNRNARHVLASASADTTVALWDLSEGKMAMNFTQHSREVQCCNWHP 415

Query: 287 ESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWV----- 341
           +   +                   LL+GS D T+K+ D     C      H +W      
Sbjct: 414 QEEQT-------------------LLTGSFDNTVKVVD-----CRSAETCHKSWTVEGEV 307

Query: 342 -RGVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAP-YVVTGS 399
            + V  H     +L+C D   +  +D ++++ + ++ AH   VT +      P  ++T S
Sbjct: 306 EKAVWNHHNPLQLLACTDKGMVYCFDIRHEKPVFSVGAHSSCVTGVCLSSQIPGLMITTS 127

Query: 400 VDQTVKVWECR 410
            D+T+KVW+ +
Sbjct: 126 EDKTMKVWDIQ 94

 Score = 43.5 bits (101), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 33/126 (26%), Positives = 55/126 (43%), Gaps = 22/126 (17%)
 Frame = -1

Query: 307 PGPFLLSGSRDKTIKMWDV----STGMCLM----------------TLVGHDNWVRGVLF 346
           PG F+  GS +  I++WD+    S G  L                 ++ GH   V  + +
Sbjct: 729 PGNFVAIGSMEPVIEIWDLDIMESVGPTLTLGSKPKKTKKKMKQKESVTGHTQAVLDLSW 550

Query: 347 HSGGKFILSCAD-DKTLRVWDYKNKRCMKTLNAHEHFVTSLDFH-KTAPYVVTGSVDQTV 404
           +   + +L+ A  D T+ +WD    +       H   V   ++H +    ++TGS D TV
Sbjct: 549 NRNARHVLASASADTTVALWDLSEGKMAMNFTQHSREVQCCNWHPQEEQTLLTGSFDNTV 370

Query: 405 KVWECR 410
           KV +CR
Sbjct: 369 KVVDCR 352

 Score = 32.3 bits (72), Expect = 0.39,   Method: Compositional matrix adjust.
 Identities = 36/154 (23%), Positives = 63/154 (40%), Gaps = 14/154 (9%)
 Frame = -1

Query: 122 VMVSASEDATIKVWDYETGDFERTLKGHTDSVQDI-------------SFDHSGKLLASC 168
           V+ SAS D T+ +WD   G        H+  VQ               SFD++ K++   
Sbjct: 531 VLASASADTTVALWDLSEGKMAMNFTQHSREVQCCNWHPQEEQTLLTGSFDNTVKVVDCR 352

Query: 169 SADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVK 228
           SA+   K W  +G E  + +  H + +  +A    G           +  ++++    V 
Sbjct: 351 SAETCHKSWTVEG-EVEKAVWNHHNPLQLLACTDKG----------MVYCFDIRHEKPVF 205

Query: 229 TFTGHREWVRMV-RPNQDGTLIASCSNDQTVRVW 261
           +   H   V  V   +Q   L+ + S D+T++VW
Sbjct: 204 SVGAHSSCVTGVCLSSQIPGLMITTSEDKTMKVW 103

 Score = 32.0 bits (71), Expect = 0.42,   Method: Compositional matrix adjust.
 Identities = 19/51 (37%), Positives = 28/51 (54%), Gaps = 5/51 (9%)
 Frame = -1

Query: 102 YALSGHRSPVTRVIFHP-VFSVMVSASEDATIKVWDYE----TGDFERTLK 147
           +++  H S VT V     +  +M++ SED T+KVWD +    T  F R LK
Sbjct: 207 FSVGAHSSCVTGVCLSSQIPGLMITTSEDKTMKVWDIQDDKPTHVFSRNLK 55
>17266
          Length = 480

 Score = 57.8 bits (138), Expect = 8e-09,   Method: Compositional matrix adjust.
 Identities = 38/139 (27%), Positives = 66/139 (47%), Gaps = 3/139 (2%)
 Frame = -1

Query: 118 PVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLW 177
           P     VS + DA+ K+WD   G  ++T  GH   +  I++  +G   A+ S D T +L+
Sbjct: 429 PDMRTFVSGACDASAKLWDVRDGMCKQTFSGHESDINAITYFPNGHAFATGSDDATCRLF 250

Query: 178 DFQGFECIRTMHGHDH---NVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHR 234
           D +  + I  M+ HD+    ++SVA   +G  ++    D    +W+V          GH 
Sbjct: 249 DIRADQEI-GMYSHDNIICGITSVAFSKSGRLLLGGYDDFNCNIWDVLKQERTGVLAGHD 73

Query: 235 EWVRMVRPNQDGTLIASCS 253
             V  +   +DG+ +A+ S
Sbjct: 72  NRVSCLGVTEDGSAVATGS 16

 Score = 56.2 bits (134), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 37/144 (25%), Positives = 65/144 (45%)
 Frame = -1

Query: 198 VAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQT 257
           +++ P+    VS + D + K+W+V+ G C +TF+GH   +  +    +G   A+ S+D T
Sbjct: 441 LSLAPDMRTFVSGACDASAKLWDVRDGMCKQTFSGHESDINAITYFPNGHAFATGSDDAT 262

Query: 258 VRVWVVATKECKAELREHEHVVECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRD 317
            R++ +   + +  +  H++++  I+    S                 K G  LL G  D
Sbjct: 261 CRLFDIRADQ-EIGMYSHDNIICGITSVAFS-----------------KSGRLLLGGYDD 136

Query: 318 KTIKMWDVSTGMCLMTLVGHDNWV 341
               +WDV        L GHDN V
Sbjct: 135 FNCNIWDVLKQERTGVLAGHDNRV 64

 Score = 53.5 bits (127), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 31/119 (26%), Positives = 54/119 (45%), Gaps = 3/119 (2%)
 Frame = -1

Query: 101 KYALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTD---SVQDIS 157
           K   SGH S +  + + P      + S+DAT +++D    D E  +  H +    +  ++
Sbjct: 354 KQTFSGHESDINAITYFPNGHAFATGSDDATCRLFDIRA-DQEIGMYSHDNIICGITSVA 178

Query: 158 FDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTI 216
           F  SG+LL     D    +WD    E    + GHD+ VS + +  +G  + + S D  +
Sbjct: 177 FSKSGRLLLGGYDDFNCNIWDVLKQERTGVLAGHDNRVSCLGVTEDGSAVATGSWDSFL 1

 Score = 53.1 bits (126), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 27/101 (26%), Positives = 54/101 (53%), Gaps = 3/101 (2%)
 Frame = -1

Query: 311 LLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNK 370
            +SG+ D + K+WDV  GMC  T  GH++ +  + +   G    + +DD T R++D +  
Sbjct: 414 FVSGACDASAKLWDVRDGMCKQTFSGHESDINAITYFPNGHAFATGSDDATCRLFDIRAD 235

Query: 371 RCMKTLNAHEHF---VTSLDFHKTAPYVVTGSVDQTVKVWE 408
           + +  + +H++    +TS+ F K+   ++ G  D    +W+
Sbjct: 234 QEIG-MYSHDNIICGITSVAFSKSGRLLLGGYDDFNCNIWD 115

 Score = 53.1 bits (126), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 33/140 (23%), Positives = 66/140 (47%), Gaps = 3/140 (2%)
 Frame = -1

Query: 163 KLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQ 222
           +   S + D + KLWD +   C +T  GH+ +++++   PNG    + S D T ++++++
Sbjct: 420 RTFVSGACDASAKLWDVRDGMCKQTFSGHESDINAITYFPNGHAFATGSDDATCRLFDIR 241

Query: 223 TGYCVKTFTGHRE---WVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVV 279
               +  ++ H      +  V  ++ G L+    +D    +W V  +E    L  H++ V
Sbjct: 240 ADQEIGMYS-HDNIICGITSVAFSKSGRLLLGGYDDFNCNIWDVLKQERTGVLAGHDNRV 64

Query: 280 ECISWAPESSYSSISEATGS 299
            C+    + S    + ATGS
Sbjct: 63  SCLGVTEDGS----AVATGS 16

 Score = 48.5 bits (114), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 36/151 (23%), Positives = 58/151 (38%), Gaps = 3/151 (1%)
 Frame = -1

Query: 255 DQTVRVWVVATKECKAELREHEHVVECISWAPESSYSSISEATGSETKKSGKPGPFLLSG 314
           D + ++W V    CK     HE  +  I++ P                     G    +G
Sbjct: 396 DASAKLWDVRDGMCKQTFSGHESDINAITYFPN--------------------GHAFATG 277

Query: 315 SRDKTIKMWDVSTGMCLMTLVGHDNWVRG---VLFHSGGKFILSCADDKTLRVWDYKNKR 371
           S D T +++D+      + +  HDN + G   V F   G+ +L   DD    +WD   + 
Sbjct: 276 SDDATCRLFDIRADQ-EIGMYSHDNIICGITSVAFSKSGRLLLGGYDDFNCNIWDVLKQE 100

Query: 372 CMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQ 402
               L  H++ V+ L   +    V TGS D 
Sbjct: 99  RTGVLAGHDNRVSCLGVTEDGSAVATGSWDS 7

 Score = 37.0 bits (84), Expect = 0.014,   Method: Compositional matrix adjust.
 Identities = 15/58 (25%), Positives = 31/58 (53%)
 Frame = -1

Query: 353 ILSCADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWECR 410
            +S A D + ++WD ++  C +T + HE  + ++ +        TGS D T ++++ R
Sbjct: 414 FVSGACDASAKLWDVRDGMCKQTFSGHESDINAITYFPNGHAFATGSDDATCRLFDIR 241
>19498
          Length = 903

 Score = 55.8 bits (133), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 49/189 (25%), Positives = 88/189 (46%), Gaps = 26/189 (13%)
 Frame = -1

Query: 104 LSGHRSPVTRVIFHPVFSVMVSASEDATIKVWD-YETGDFERTLKGHTDSVQDISFDHSG 162
           L GH   V  + + P    + S S D TI VW+  +  +    ++GH   V+ +++D  G
Sbjct: 621 LRGHAGDVLDLAWSPQDLWLASCSVDNTIVVWNALKFSEQVAVIRGHAGMVKGVTWDPVG 442

Query: 163 KLLASCSADMTIKLW---DFQGFECIRTMH---GHDHNVSSVAIMPNGDHIVSA----SR 212
           + LAS S D T+++W   D++   C+++     G   +V  +   P+G+H+VSA    + 
Sbjct: 441 RYLASQSDDKTLRVWRTSDWKEETCVKSCFKECGGTTHVLRLNWSPDGNHVVSAHAMNNA 262

Query: 213 DKTIKMWEVQTGYCVKTFTGHREWVRMVRPN---------------QDGTLIASCSNDQT 257
             T ++ E         F GHR+ + +VR N               Q  +  A  S D++
Sbjct: 261 XPTAQIIERNGWGTSLDFVGHRKAITVVRFNPKILSKQIKKSAEKQQQYSCCAIGSKDRS 82

Query: 258 VRVWVVATK 266
           + +W+ A +
Sbjct: 81  LSIWLTALR 55

 Score = 52.4 bits (124), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 29/76 (38%), Positives = 42/76 (55%), Gaps = 1/76 (1%)
 Frame = -1

Query: 145 TLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQGF-ECIRTMHGHDHNVSSVAIMPN 203
           TL+GH   V D+++      LASCS D TI +W+   F E +  + GH   V  V   P 
Sbjct: 624 TLRGHAGDVLDLAWSPQDLWLASCSVDNTIVVWNALKFSEQVAVIRGHAGMVKGVTWDPV 445

Query: 204 GDHIVSASRDKTIKMW 219
           G ++ S S DKT+++W
Sbjct: 444 GRYLASQSDDKTLRVW 397

 Score = 51.6 bits (122), Expect = 5e-07,   Method: Compositional matrix adjust.
 Identities = 45/170 (26%), Positives = 73/170 (42%), Gaps = 25/170 (14%)
 Frame = -1

Query: 146 LKGHTDSVQDISFDHSGKLLASCSADMTIKLWDF-QGF----------------ECIRTM 188
           +  H   V  + +  +GK LAS   D  I +W   +GF                  + T+
Sbjct: 798 MDSHLGCVNCVRWSENGKFLASGGDDKLIMIWQISRGFGSGKSFGSNVTILEHWRSVATL 619

Query: 189 HGHDHNVSSVAIMPNGDHIVSASRDKTIKMWE-VQTGYCVKTFTGHREWVRMVRPNQDGT 247
            GH  +V  +A  P    + S S D TI +W  ++    V    GH   V+ V  +  G 
Sbjct: 618 RGHAGDVLDLAWSPQDLWLASCSVDNTIVVWNALKFSEQVAVIRGHAGMVKGVTWDPVGR 439

Query: 248 LIASCSNDQTVRVWVVA-------TKECKAELREHEHVVECISWAPESSY 290
            +AS S+D+T+RVW  +        K C  E     HV+  ++W+P+ ++
Sbjct: 438 YLASQSDDKTLRVWRTSDWKEETCVKSCFKECGGTTHVLR-LNWSPDGNH 292

 Score = 49.3 bits (116), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 42/164 (25%), Positives = 72/164 (43%), Gaps = 21/164 (12%)
 Frame = -1

Query: 233 HREWVRMVRPNQDGTLIASCSNDQTVRVWVVATK-----------------ECKAELREH 275
           H   V  VR +++G  +AS  +D+ + +W ++                      A LR H
Sbjct: 789 HLGCVNCVRWSENGKFLASGGDDKLIMIWQISRGFGSGKSFGSNVTILEHWRSVATLRGH 610

Query: 276 EHVVECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWD-VSTGMCLMTL 334
              V  ++W+P+  +                    L S S D TI +W+ +     +  +
Sbjct: 609 AGDVLDLAWSPQDLW--------------------LASCSVDNTIVVWNALKFSEQVAVI 490

Query: 335 VGHDNWVRGVLFHSGGKFILSCADDKTLRVW---DYKNKRCMKT 375
            GH   V+GV +   G+++ S +DDKTLRVW   D+K + C+K+
Sbjct: 489 RGHAGMVKGVTWDPVGRYLASQSDDKTLRVWRTSDWKEETCVKS 358

 Score = 33.1 bits (74), Expect = 0.19,   Method: Compositional matrix adjust.
 Identities = 27/102 (26%), Positives = 38/102 (37%), Gaps = 17/102 (16%)
 Frame = -1

Query: 324 DVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNK------------- 370
           DV   +C M    H   V  V +   GKF+ S  DDK + +W                  
Sbjct: 822 DVPRVLCQMD--SHLGCVNCVRWSENGKFLASGGDDKLIMIWQISRGFGSGKSFGSNVTI 649

Query: 371 ----RCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWE 408
               R + TL  H   V  L +     ++ + SVD T+ VW 
Sbjct: 648 LEHWRSVATLRGHAGDVLDLAWSPQDLWLASCSVDNTIVVWN 523
>37180
          Length = 681

 Score = 54.3 bits (129), Expect = 8e-08,   Method: Compositional matrix adjust.
 Identities = 26/78 (33%), Positives = 46/78 (58%), Gaps = 1/78 (1%)
 Frame = +1

Query: 146 LKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQGFE-CIRTMHGHDHNVSSVAIMPNG 204
           L GH   + D+    + +L+ + S DMT +LWDF+     +    GH   V+S A+  +G
Sbjct: 7   LNGHDQELSDVHAHPTQRLVVTSSKDMTFRLWDFRDSALLVNVFQGHTQPVTS-AVFASG 183

Query: 205 DHIVSASRDKTIKMWEVQ 222
           D +VS S D+T+++W+++
Sbjct: 184 DKVVSGSDDRTVRVWDMR 237

 Score = 47.4 bits (111), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 26/78 (33%), Positives = 42/78 (53%), Gaps = 1/78 (1%)
 Frame = +1

Query: 334 LVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNKRCM-KTLNAHEHFVTSLDFHKTA 392
           L GHD  +  V  H   + +++ + D T R+WD+++   +      H   VTS  F  + 
Sbjct: 7   LNGHDQELSDVHAHPTQRLVVTSSKDMTFRLWDFRDSALLVNVFQGHTQPVTSAVF-ASG 183

Query: 393 PYVVTGSVDQTVKVWECR 410
             VV+GS D+TV+VW+ R
Sbjct: 184 DKVVSGSDDRTVRVWDMR 237

 Score = 47.4 bits (111), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 27/79 (34%), Positives = 45/79 (56%), Gaps = 5/79 (6%)
 Frame = +1

Query: 310 FLLSGSRDKTIKMWDVSTGMCLMTLV-GHDNWVRGVLFHSGGKFILSCADDKTLRVWDYK 368
            +++ S+D T ++WD      L+ +  GH   V   +F SG K ++S +DD+T+RVWD +
Sbjct: 61  LVVTSSKDMTFRLWDFRDSALLVNVFQGHTQPVTSAVFASGDK-VVSGSDDRTVRVWDMR 237

Query: 369 NKR----CMKTLNAHEHFV 383
           N R     ++T +A   FV
Sbjct: 238 NMRSPIATIRTDSAVNRFV 294

 Score = 46.2 bits (108), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 25/83 (30%), Positives = 44/83 (53%), Gaps = 1/83 (1%)
 Frame = +1

Query: 103 ALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDY-ETGDFERTLKGHTDSVQDISFDHS 161
            L+GH   ++ V  HP   ++V++S+D T ++WD+ ++       +GHT  V    F  S
Sbjct: 4   VLNGHDQELSDVHAHPTQRLVVTSSKDMTFRLWDFRDSALLVNVFQGHTQPVTSAVF-AS 180

Query: 162 GKLLASCSADMTIKLWDFQGFEC 184
           G  + S S D T+++WD +    
Sbjct: 181 GDKVVSGSDDRTVRVWDMRNMRS 249
>19863
          Length = 502

 Score = 54.3 bits (129), Expect = 9e-08,   Method: Compositional matrix adjust.
 Identities = 25/61 (40%), Positives = 38/61 (62%)
 Frame = +1

Query: 308 GPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDY 367
           G  L+SGS D +I +WDV  G+  + L GH  WV  V F     ++LSC++D T+R+W+ 
Sbjct: 7   GLQLVSGSSDMSIVVWDVENGVQKLRLQGHAGWVNDVHFSQDQCWLLSCSNDNTVRIWNI 186

Query: 368 K 368
           +
Sbjct: 187 E 189

 Score = 52.4 bits (124), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 27/74 (36%), Positives = 40/74 (54%)
 Frame = +1

Query: 203 NGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWV 262
           +G  +VS S D +I +W+V+ G       GH  WV  V  +QD   + SCSND TVR+W 
Sbjct: 4   DGLQLVSGSSDMSIVVWDVENGVQKLRLQGHAGWVNDVHFSQDQCWLLSCSNDNTVRIWN 183

Query: 263 VATKECKAELREHE 276
           +   +    + EH+
Sbjct: 184 IEESDQIPIVMEHK 225

 Score = 49.3 bits (116), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 23/58 (39%), Positives = 33/58 (56%)
 Frame = +1

Query: 123 MVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQ 180
           +VS S D +I VWD E G  +  L+GH   V D+ F      L SCS D T+++W+ +
Sbjct: 16  LVSGSSDMSIVVWDVENGVQKLRLQGHAGWVNDVHFSQDQCWLLSCSNDNTVRIWNIE 189

 Score = 34.7 bits (78), Expect = 0.071,   Method: Compositional matrix adjust.
 Identities = 21/74 (28%), Positives = 39/74 (52%), Gaps = 1/74 (1%)
 Frame = +1

Query: 162 GKLLASCSADMTIKLWDFQ-GFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWE 220
           G  L S S+DM+I +WD + G + +R + GH   V+ V    +   ++S S D T+++W 
Sbjct: 7   GLQLVSGSSDMSIVVWDVENGVQKLR-LQGHAGWVNDVHFSQDQCWLLSCSNDNTVRIWN 183

Query: 221 VQTGYCVKTFTGHR 234
           ++    +     H+
Sbjct: 184 IEESDQIPIVMEHK 225

 Score = 28.9 bits (63), Expect = 3.6,   Method: Compositional matrix adjust.
 Identities = 14/42 (33%), Positives = 21/42 (50%)
 Frame = +1

Query: 100 EKYALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGD 141
           +K  L GH   V  V F      ++S S D T+++W+ E  D
Sbjct: 73  QKLRLQGHAGWVNDVHFSQDQCWLLSCSNDNTVRIWNIEESD 198
>10162
          Length = 1629

 Score = 53.5 bits (127), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 65/320 (20%), Positives = 119/320 (37%), Gaps = 46/320 (14%)
 Frame = +3

Query: 133 KVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDF--QGFECIRTMHG 190
           ++W YE G     L+ H  +   ++    G+          + LW    Q +  ++ +  
Sbjct: 6   QIWSYECGSDITWLQWHGGAHVLLAGTQGGE----------VWLWQVPSQDYSKMKMLQS 155

Query: 191 HDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQ------ 244
           H        I+PNG ++     D  +K+W+++TG  V T      W   V P +      
Sbjct: 156 HGQPSLCGKILPNGKYVCVGYSDGVVKLWDLKTGTAVHT------WQHSVMPEEEMPERN 317

Query: 245 ----------------------------DGTLIASCSNDQTVRVWVVATKE------CKA 270
                                       D  LI S   D T +V+ V++ +      C A
Sbjct: 318 SSDEEDGEEVEVEREEDTVAILCVDCSADNALIMSGCADATAKVFNVSSGKLXSAFNCAA 497

Query: 271 --ELREHEHVVECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTG 328
             + ++ ++ VE +++ P S Y++ +  +GS                    +++WD+ T 
Sbjct: 498 SQDSQDKDNSVESVAFCPVSPYAATATNSGS--------------------VQVWDLPTS 617

Query: 329 MCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDF 388
           +   +   H   V  + + S    + +   D  +RVWD ++      L  H      LDF
Sbjct: 618 VARHSF-QHPEGVCKLQWSSSTALLYTACLDGVMRVWDARSGASKAVLTGHARNSCILDF 794

Query: 389 HKT--APYVVTGSVDQTVKV 406
             T     +V+GS D T +V
Sbjct: 795 DVTRDGTCLVSGSEDGTARV 854

 Score = 31.6 bits (70), Expect = 0.62,   Method: Compositional matrix adjust.
 Identities = 19/72 (26%), Positives = 34/72 (47%), Gaps = 2/72 (2%)
 Frame = +3

Query: 107 HRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFD--HSGKL 164
           H   V ++ +    +++ +A  D  ++VWD  +G  +  L GH  +   + FD    G  
Sbjct: 639 HPEGVCKLQWSSSTALLYTACLDGVMRVWDARSGASKAVLTGHARNSCILDFDVTRDGTC 818

Query: 165 LASCSADMTIKL 176
           L S S D T ++
Sbjct: 819 LVSGSEDGTARV 854
>03395
          Length = 2795

 Score = 53.5 bits (127), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 30/112 (26%), Positives = 50/112 (44%), Gaps = 1/112 (0%)
 Frame = +2

Query: 123 MVSASEDATIKVWDYETGDFERTLKG-HTDSVQDISFDHSGKLLASCSADMTIKLWDFQG 181
           ++++  D  I  W+   G   R L+G  T ++  I  D  G+ + +   D  +KLW +  
Sbjct: 314 ILTSGTDHKIGYWEVGDGGLLRELEGSQTGAINTIDIDRDGQTILTGGEDSLLKLWRYNE 493

Query: 182 FECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGH 233
            E   T  GH + ++   I PN  +IVS   D  + +W+   G  V     H
Sbjct: 494 GEVTHTGIGHSNQITKARICPNRHYIVSGGEDGALHIWKFPDGC*VDCLPRH 649

 Score = 50.1 bits (118), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 46/195 (23%), Positives = 68/195 (34%), Gaps = 48/195 (24%)
 Frame = +2

Query: 78  EFTSGGPLGQKR------DPKEWIPRPPEKYALSGHRSPVTRVIFHPVFSVMVSASEDAT 131
           +  SGG  GQ R      D      R      +  H+  VT +  H      VSAS D +
Sbjct: 38  KLVSGGGEGQVRVWDIVKDMLTGKTRGDLVANMKEHKGKVTAIQIHTNDRCCVSASTDGS 217

Query: 132 IKVWD---------------------------------------YETGD--FERTLKG-H 149
             +WD                                       +E GD    R L+G  
Sbjct: 218 TIIWDLITNTRSQIVLANTLFKCVCFGGKDLHILTSGTDHKIGYWEVGDGGLLRELEGSQ 397

Query: 150 TDSVQDISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVS 209
           T ++  I  D  G+ + +   D  +KLW +   E   T  GH + ++   I PN  +IVS
Sbjct: 398 TGAINTIDIDRDGQTILTGGEDSLLKLWRYNEGEVTHTGIGHSNQITKARICPNRHYIVS 577

Query: 210 ASRDKTIKMWEVQTG 224
              D  + +W+   G
Sbjct: 578 GGEDGALHIWKFPDG 622

 Score = 47.0 bits (110), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 44/224 (19%), Positives = 87/224 (38%), Gaps = 9/224 (4%)
 Frame = +2

Query: 194 NVSSVAIMPNGDHIVSASRDKTIKMWEV--------QTGYCVKTFTGHREWVRMVRPNQD 245
            V+++A+   G  +VS   +  +++W++          G  V     H+  V  ++ + +
Sbjct: 2   GVTAIAVTSCGTKLVSGGGEGQVRVWDIVKDMLTGKTRGDLVANMKEHKGKVTAIQIHTN 181

Query: 246 GTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSSISEATGSETKKSG 305
                S S D +  +W + T   ++++     + +C+ +                    G
Sbjct: 182 DRCCVSASTDGSTIIWDLITNT-RSQIVLANTLFKCVCFG-------------------G 301

Query: 306 KPGPFLLSGSRDKTIKMWDVSTGMCLMTLVG-HDNWVRGVLFHSGGKFILSCADDKTLRV 364
           K    L SG+ D  I  W+V  G  L  L G     +  +     G+ IL+  +D  L++
Sbjct: 302 KDLHILTSGT-DHKIGYWEVGDGGLLRELEGSQTGAINTIDIDRDGQTILTGGEDSLLKL 478

Query: 365 WDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWE 408
           W Y       T   H + +T         Y+V+G  D  + +W+
Sbjct: 479 WRYNEGEVTHTGIGHSNQITKARICPNRHYIVSGGEDGALHIWK 610

 Score = 41.2 bits (95), Expect = 8e-04,   Method: Compositional matrix adjust.
 Identities = 46/224 (20%), Positives = 82/224 (36%), Gaps = 8/224 (3%)
 Frame = +2

Query: 152 SVQDISFDHSGKLLASCSADMTIKLWDF--------QGFECIRTMHGHDHNVSSVAIMPN 203
            V  I+    G  L S   +  +++WD            + +  M  H   V+++ I  N
Sbjct: 2   GVTAIAVTSCGTKLVSGGGEGQVRVWDIVKDMLTGKTRGDLVANMKEHKGKVTAIQIHTN 181

Query: 204 GDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVV 263
               VSAS D +  +W++ T    +    +  +  +    +D  ++ S   D  +  W V
Sbjct: 182 DRCCVSASTDGSTIIWDLITNTRSQIVLANTLFKCVCFGGKDLHILTS-GTDHKIGYWEV 358

Query: 264 ATKECKAELREHEHVVECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMW 323
                   LRE E                 S+     T    + G  +L+G  D  +K+W
Sbjct: 359 GD---GGLLRELEG----------------SQTGAINTIDIDRDGQTILTGGEDSLLKLW 481

Query: 324 DVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDY 367
             + G    T +GH N +          +I+S  +D  L +W +
Sbjct: 482 RYNEGEVTHTGIGHSNQITKARICPNRHYIVSGGEDGALHIWKF 613
>02090
          Length = 1841

 Score = 52.4 bits (124), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 25/99 (25%), Positives = 45/99 (45%), Gaps = 2/99 (2%)
 Frame = -3

Query: 128  EDATIKVWDYETGD--FERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQGFECI 185
            E +T+ +WD  T     +  L     +   ++    GK+  SC +D  I +WD      +
Sbjct: 1698 EASTLSIWDLATPTPRIKAELTSSAPACYALAISPDGKVCFSCCSDGNIAVWDLHNQTLV 1519

Query: 186  RTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTG 224
            R   GH    S + I P+G  + +   D T++ W+++ G
Sbjct: 1518 RQFQGHTDGASCIDISPDGTKLWTGGLDNTVRSWDLREG 1402

 Score = 50.4 bits (119), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 49/216 (22%), Positives = 85/216 (39%), Gaps = 4/216 (1%)
 Frame = -3

Query: 197  SVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQ 256
            ++AI P+G    S   D  I +W++     V+ F GH +    +  + DGT + +   D 
Sbjct: 1611 ALAISPDGKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISPDGTKLWTGGLDN 1432

Query: 257  TVRVWVVATKECKAELREHEHVVECIS--WAPESSYSSIS-EATGSETKKSGKPGPFLLS 313
            TVR W +       +L++H+   +  S  + P   + ++  E++  E     KP  + L 
Sbjct: 1431 TVRSWDLREGR---QLQQHDFSSQIFSLGYCPTGEWLAVGMESSNVEVLHHSKPDKYQLH 1261

Query: 314  GSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNKRCM 373
                                   H++ V  + F   GK+ +S   D  L  W  +     
Sbjct: 1260 L----------------------HESCVLSLKFAYCGKWFVSTGKDNLLNAW--RTPYGA 1153

Query: 374  KTLNAHEHF-VTSLDFHKTAPYVVTGSVDQTVKVWE 408
                + E   V S D      Y+VTGS D+   ++E
Sbjct: 1152 SIFQSKESSSVLSCDIAADDKYIVTGSGDKKATLYE 1045

 Score = 44.3 bits (103), Expect = 9e-05,   Method: Compositional matrix adjust.
 Identities = 30/112 (26%), Positives = 42/112 (37%), Gaps = 2/112 (1%)
 Frame = -3

Query: 96   PRPPEKYALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQD 155
            P P  K  L+        +   P   V  S   D  I VWD       R  +GHTD    
Sbjct: 1662 PTPRIKAELTSSAPACYALAISPDGKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGASC 1483

Query: 156  ISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHN--VSSVAIMPNGD 205
            I     G  L +   D T++ WD +     R +  HD +  + S+   P G+
Sbjct: 1482 IDISPDGTKLWTGGLDNTVRSWDLREG---RQLQQHDFSSQIFSLGYCPTGE 1336

 Score = 43.1 bits (100), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 23/94 (24%), Positives = 39/94 (41%), Gaps = 2/94 (2%)
 Frame = -3

Query: 319  TIKMWDVSTGMCLMT--LVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTL 376
            T+ +WD++T    +   L         +     GK   SC  D  + VWD  N+  ++  
Sbjct: 1689 TLSIWDLATPTPRIKAELTSSAPACYALAISPDGKVCFSCCSDGNIAVWDLHNQTLVRQF 1510

Query: 377  NAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWECR 410
              H    + +D       + TG +D TV+ W+ R
Sbjct: 1509 QGHTDGASCIDISPDGTKLWTGGLDNTVRSWDLR 1408
>27806
          Length = 419

 Score = 52.0 bits (123), Expect = 4e-07,   Method: Compositional matrix adjust.
 Identities = 22/61 (36%), Positives = 34/61 (55%), Gaps = 1/61 (1%)
 Frame = -1

Query: 306 KPG-PFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRV 364
           +PG P + + S D T +++ + TG C++T  GH   V  V FH G   +L+ + D T  V
Sbjct: 398 RPGHPIIGTASADHTARIYSIETGACVLTYGGHQGSVNAVRFHPGQDLVLTASGDHTAHV 219

Query: 365 W 365
           W
Sbjct: 218 W 216

 Score = 47.8 bits (112), Expect = 8e-06,   Method: Compositional matrix adjust.
 Identities = 24/57 (42%), Positives = 34/57 (59%), Gaps = 2/57 (3%)
 Frame = -1

Query: 207 IVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVR--PNQDGTLIASCSNDQTVRVW 261
           I +AS D T +++ ++TG CV T+ GH+  V  VR  P QD  L+ + S D T  VW
Sbjct: 380 IGTASADHTARIYSIETGACVLTYGGHQGSVNAVRFHPGQD--LVLTASGDHTAHVW 216

 Score = 42.7 bits (99), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 18/59 (30%), Positives = 33/59 (55%)
 Frame = -1

Query: 164 LLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQ 222
           ++ + SAD T +++  +   C+ T  GH  +V++V   P  D +++AS D T  +W  Q
Sbjct: 383 IIGTASADHTARIYSIETGACVLTYGGHQGSVNAVRFHPGQDLVLTASGDHTAHVWRAQ 207

 Score = 39.7 bits (91), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 18/62 (29%), Positives = 29/62 (46%)
 Frame = -1

Query: 349 GGKFILSCADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWE 408
           G   I + + D T R++  +   C+ T   H+  V ++ FH     V+T S D T  VW 
Sbjct: 392 GHPIIGTASADHTARIYSIETGACVLTYGGHQGSVNAVRFHPGQDLVLTASGDHTAHVWR 213

Query: 409 CR 410
            +
Sbjct: 212 AQ 207

 Score = 36.6 bits (83), Expect = 0.017,   Method: Compositional matrix adjust.
 Identities = 20/66 (30%), Positives = 31/66 (46%)
 Frame = -1

Query: 115 IFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSADMTI 174
           +  P   ++ +AS D T +++  ETG    T  GH  SV  + F     L+ + S D T 
Sbjct: 404 VSRPGHPIIGTASADHTARIYSIETGACVLTYGGHQGSVNAVRFHPGQDLVLTASGDHTA 225

Query: 175 KLWDFQ 180
            +W  Q
Sbjct: 224 HVWRAQ 207

 Score = 29.3 bits (64), Expect = 3.0,   Method: Compositional matrix adjust.
 Identities = 13/30 (43%), Positives = 18/30 (60%)
 Frame = -1

Query: 106 GHRSPVTRVIFHPVFSVMVSASEDATIKVW 135
           GH+  V  V FHP   ++++AS D T  VW
Sbjct: 305 GHQGSVNAVRFHPGQDLVLTASGDHTAHVW 216
>03387
          Length = 1891

 Score = 52.0 bits (123), Expect = 5e-07,   Method: Compositional matrix adjust.
 Identities = 35/112 (31%), Positives = 57/112 (50%), Gaps = 12/112 (10%)
 Frame = +1

Query: 311 LLSGSRDKTIKMWDVSTGM-------CLMTLVGHDNWVRGVLFHSGGKFIL-SCADDKTL 362
           LLS S D TI +WD+++               GH + V  V +H   + +  S ADD+ L
Sbjct: 409 LLSASDDHTICLWDINSTQRESRVVDAHTIFTGHTSVVEDVAWHLLHESLFGSVADDQKL 588

Query: 363 RVWDYKNKRCMK---TLNAHEHFVTSLDFHKTAPYVV-TGSVDQTVKVWECR 410
            +WD ++    K    ++AH   V  L F+  + +++ TGS D+TV +W+ R
Sbjct: 589 MIWDTRSNTTSKPSHVVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLR 744

 Score = 52.0 bits (123), Expect = 5e-07,   Method: Compositional matrix adjust.
 Identities = 50/192 (26%), Positives = 93/192 (48%), Gaps = 18/192 (9%)
 Frame = +1

Query: 88  KRDPK-EWIPRPPEKYALSGHRSPVTRVIFHPVFSV-MVSASEDATIKVWDYETG----- 140
           K DP  E IP    +  L GH+     + ++P  +  ++SAS+D TI +WD  +      
Sbjct: 310 KPDPSGECIP----ELRLKGHQKEGYGLSWNPNLNGHLLSASDDHTICLWDINSTQRESR 477

Query: 141 --DFERTLKGHTDSVQDISFD--HSGKLLASCSADMTIKLWDFQGFECIRTMH---GHDH 193
             D      GHT  V+D+++   H   L  S + D  + +WD +     +  H    H  
Sbjct: 478 VVDAHTIFTGHTSVVEDVAWHLLHE-SLFGSVADDQKLMIWDTRSNTTSKPSHVVDAHTA 654

Query: 194 NVSSVAIMPNGDHIVS-ASRDKTIKMWEVQT-GYCVKTFTGHREWVRMVR--PNQDGTLI 249
            V+ ++  P  + I++  S DKT+ +W+++     + +F  H++ +  V+  P+ + T++
Sbjct: 655 EVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPHNE-TIL 831

Query: 250 ASCSNDQTVRVW 261
           AS   D+ + VW
Sbjct: 832 ASSGTDRRLHVW 867

 Score = 50.8 bits (120), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 59/257 (22%), Positives = 101/257 (39%), Gaps = 31/257 (12%)
 Frame = +1

Query: 183 ECIRTMH--GHDHNVSSVAIMPN-GDHIVSASRDKTIKMWEVQTGY-------CVKTFTG 232
           ECI  +   GH      ++  PN   H++SAS D TI +W++ +             FTG
Sbjct: 328 ECIPELRLKGHQKEGYGLSWNPNLNGHLLSASDDHTICLWDINSTQRESRVVDAHTIFTG 507

Query: 233 HREWVRMVRPN-QDGTLIASCSNDQTVRVWVV---ATKECKAELREHEHVVECISWAPES 288
           H   V  V  +    +L  S ++DQ + +W      T +    +  H   V C+S+ P S
Sbjct: 508 HTSVVEDVAWHLLHESLFGSVADDQKLMIWDTRSNTTSKPSHVVDAHTAEVNCLSFNPYS 687

Query: 289 SYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDV-STGMCLMTLVGHDNWVRGVLFH 347
            +                    L +GS DKT+ +WD+ +  + L +   H + +  V + 
Sbjct: 688 EF-------------------ILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWS 810

Query: 348 SGGKFIL-SCADDKTLRVWDYKN--------------KRCMKTLNAHEHFVTSLDFHKTA 392
              + IL S   D+ L VWD                    +     H   ++   ++   
Sbjct: 811 PHNETILASSGTDRRLHVWDLSKIGEEQLPEDAEDGPPELLFIHGGHTAKISDFSWNPNE 990

Query: 393 PYVVTG-SVDQTVKVWE 408
           P++V   S D  ++VW+
Sbjct: 991 PWIVCSVSEDNIMQVWQ 1041

 Score = 47.0 bits (110), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 34/125 (27%), Positives = 64/125 (51%), Gaps = 7/125 (5%)
 Frame = +1

Query: 104 LSGHRSPVTRVIFHPVF-SVMVSASEDATIKVWDYE---TGDFERTLKGHTDSVQDISFD 159
            +GH S V  V +H +  S+  S ++D  + +WD     T      +  HT  V  +SF+
Sbjct: 499 FTGHTSVVEDVAWHLLHESLFGSVADDQKLMIWDTRSNTTSKPSHVVDAHTAEVNCLSFN 678

Query: 160 -HSGKLLASCSADMTIKLWDFQGFEC-IRTMHGHDHNVSSVAIMPNGDHIVSAS-RDKTI 216
            +S  +LA+ SAD T+ LWD +  +  + +   H   +  V   P+ + I+++S  D+ +
Sbjct: 679 PYSEFILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRL 858

Query: 217 KMWEV 221
            +W++
Sbjct: 859 HVWDL 873
>27270
          Length = 1078

 Score = 51.2 bits (121), Expect = 8e-07,   Method: Compositional matrix adjust.
 Identities = 39/159 (24%), Positives = 70/159 (44%), Gaps = 18/159 (11%)
 Frame = +2

Query: 121 SVMVSASEDATIKVWDYETGDFERTL-KGHTDSVQDISFDHSGKLLASCSADMTIKLWDF 179
           +V+   S D ++ ++  ET  +   L KGH+ +V D+ +   G+ L S S D  +  W+ 
Sbjct: 182 AVVAVGSADGSVGLYSVETHTYTHMLNKGHSKAVTDMCWRADGRTLYSSSLDGHVIGWNV 361

Query: 180 QGFECI---RTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREW 236
                I   +   G  H V  V +  +   + +   D TIKMW++ T   ++ F+GH   
Sbjct: 362 NTLHMIEKWKATSGRHHGVHCVCLCSSSRLLTA---DHTIKMWDLTTKNVLQEFSGHSTE 532

Query: 237 VRMVRP--------------NQDGTLIASCSNDQTVRVW 261
           V  + P              N    + ++ + D+T+ VW
Sbjct: 533 VIKLLPVLKPSSEQNDIGDSNLACYVFSAAAADRTINVW 649

 Score = 28.5 bits (62), Expect = 5.4,   Method: Compositional matrix adjust.
 Identities = 47/178 (26%), Positives = 67/178 (37%), Gaps = 19/178 (10%)
 Frame = +2

Query: 207 IVSASRDKTIKMWEVQT-GYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVAT 265
           +   S D ++ ++ V+T  Y      GH + V  +    DG  + S S D  V  W V T
Sbjct: 188 VAVGSADGSVGLYSVETHTYTHMLNKGHSKAVTDMCWRADGRTLYSSSLDGHVIGWNVNT 367

Query: 266 ----KECKAELREHEHVVECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIK 321
               ++ KA    H H V C+     S                      LL+   D TIK
Sbjct: 368 LHMIEKWKATSGRH-HGVHCVCLCSSSR---------------------LLTA--DHTIK 475

Query: 322 MWDVSTGMCLMTLVGHDNWVRGVL--------FHSGGKFILSC------ADDKTLRVW 365
           MWD++T   L    GH   V  +L         +  G   L+C      A D+T+ VW
Sbjct: 476 MWDLTTKNVLQEFSGHSTEVIKLLPVLKPSSEQNDIGDSNLACYVFSAAAADRTINVW 649
>29912
          Length = 510

 Score = 49.7 bits (117), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 38/145 (26%), Positives = 68/145 (46%), Gaps = 6/145 (4%)
 Frame = +3

Query: 148 GHTDSVQDISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHI 207
           G  + +  +S+   G  LA  ++   +++WD    + +RTM GH   V S++   N   +
Sbjct: 3   GPEEYIGAVSWIKEGNYLALGTSTGEVQVWDVTQQKKLRTMAGHAARVGSLSW--NSFIV 176

Query: 208 VSASRDKTIKMWEVQTG-YCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATK 266
            S SR   I   +V+   + V T +GH + V  +R + DG  +AS +ND  + VW     
Sbjct: 177 SSGSRSGNIHHHDVRVADHHVGTLSGHSQEVCGLRWSPDGKYLASGANDNLLCVWPAQVT 356

Query: 267 ECKA-----ELREHEHVVECISWAP 286
              +        +H+  V+ ++W P
Sbjct: 357 GGNSTQPLHTFSQHQAAVKALAWCP 431

 Score = 35.4 bits (80), Expect = 0.041,   Method: Compositional matrix adjust.
 Identities = 29/115 (25%), Positives = 53/115 (46%), Gaps = 6/115 (5%)
 Frame = +3

Query: 132 IKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQ-GFECIRTMHG 190
           ++VWD       RT+ GH   V  +S++    +++S S    I   D +     + T+ G
Sbjct: 81  VQVWDVTQQKKLRTMAGHAARVGSLSWN--SFIVSSGSRSGNIHHHDVRVADHHVGTLSG 254

Query: 191 HDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQ-TG----YCVKTFTGHREWVRMV 240
           H   V  +   P+G ++ S + D  + +W  Q TG      + TF+ H+  V+ +
Sbjct: 255 HSQEVCGLRWSPDGKYLASGANDNLLCVWPAQVTGGNSTQPLHTFSQHQAAVKAL 419

 Score = 34.3 bits (77), Expect = 0.11,   Method: Compositional matrix adjust.
 Identities = 39/163 (23%), Positives = 68/163 (41%), Gaps = 6/163 (3%)
 Frame = +3

Query: 232 GHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYS 291
           G  E++  V   ++G  +A  ++   V+VW V  ++    +  H   V  +SW   +S+ 
Sbjct: 3   GPEEYIGAVSWIKEGNYLALGTSTGEVQVWDVTQQKKLRTMAGHAARVGSLSW---NSF- 170

Query: 292 SISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTG-MCLMTLVGHDNWVRGVLFHSGG 350
                              + SGSR   I   DV      + TL GH   V G+ +   G
Sbjct: 171 ------------------IVSSGSRSGNIHHHDVRVADHHVGTLSGHSQEVCGLRWSPDG 296

Query: 351 KFILSCADDKTLRVWDYK-----NKRCMKTLNAHEHFVTSLDF 388
           K++ S A+D  L VW  +     + + + T + H+  V +L +
Sbjct: 297 KYLASGANDNLLCVWPAQVTGGNSTQPLHTFSQHQAAVKALAW 425
>13890
          Length = 630

 Score = 49.3 bits (116), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 41/166 (24%), Positives = 74/166 (44%), Gaps = 16/166 (9%)
 Frame = +1

Query: 116 FHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDS---VQDISFDHSGKLLASC---- 168
           FHPV   +V+      I+VWD    +    +  H +    VQD+ F H G+ + SC    
Sbjct: 4   FHPVTPHLVATGTTDCIQVWDVRHPEVPVRVLTHKEQLGQVQDVMFSHDGQEVFSCGDVV 183

Query: 169 ---SADMTIKLWDFQ-GFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTG 224
              S+D +I  WDF+ G      +    + V+ + + P     ++ ++   I ++  Q  
Sbjct: 184 SRESSDRSIMAWDFRTGVILSNQIFQERYTVTRLMLHPYQSQFLAQTQAGYIAVFSTQRP 363

Query: 225 YCV---KTFTGHREWVRMVRP--NQDGTLIASCSNDQTVRVWVVAT 265
           Y +   K F GH+     +    +QDG+++ S S+D  +  +   T
Sbjct: 364 YKMNKNKRFEGHKTAGYNIGASLSQDGSIVYSGSSDGKLHCYSFNT 501
>15118
          Length = 1074

 Score = 48.5 bits (114), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 41/178 (23%), Positives = 77/178 (43%), Gaps = 6/178 (3%)
 Frame = +3

Query: 140 GDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGH---DHNVS 196
           G F  T+  H   V+ ++FD    LL +   D  IK W F   +  R +         +S
Sbjct: 165 GSFGDTVA-HVSGVRGVAFDAFNCLLITAGGDCDIKFWRFGSRDRARVLLKELKMSEGIS 341

Query: 197 SVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQ 256
            + +  + + +     D T+ + +V T   V+ F+GH   +  +  + DG  + + S D 
Sbjct: 342 RILLHRDSNMLAVVLEDFTVSVIDVDTLRVVRVFSGHSNSITDLSFSGDGRWLITASMDC 521

Query: 257 TVRVWVVATKECKAELREHEHVVECISWAPESSYSSISEATGSE---TKKSGKPGPFL 311
           TVR W +           H  +++C  +A E++ +S++ +   +   T   G  G +L
Sbjct: 522 TVRTWSLV----------HGRLIDC--FAVEAAVTSLTMSPSQDFLATSHVGDVGVYL 659

 Score = 41.6 bits (96), Expect = 6e-04,   Method: Compositional matrix adjust.
 Identities = 49/233 (21%), Positives = 90/233 (38%), Gaps = 7/233 (3%)
 Frame = +3

Query: 182 FECIRTMHGHDHNVS---SVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTF---TGHRE 235
            +C R  HG  H  +   +V I   G+++        + ++ +Q+G    +F     H  
Sbjct: 18  LDCKRFHHGAQHRFTTAQAVDISSCGNYVAVGYSSGHLDIYNLQSGKHRGSFGDTVAHVS 197

Query: 236 WVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSSISE 295
            VR V  +    L+ +   D  ++ W   +++    L +   + E IS            
Sbjct: 198 GVRGVAFDAFNCLLITAGGDCDIKFWRFGSRDRARVLLKELKMSEGISRILLH------- 356

Query: 296 ATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILS 355
                     +    L     D T+ + DV T   +    GH N +  + F   G+++++
Sbjct: 357 ----------RDSNMLAVVLEDFTVSVIDVDTLRVVRVFSGHSNSITDLSFSGDGRWLIT 506

Query: 356 CADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSV-DQTVKVW 407
            + D T+R W   + R +    A E  VTSL    +  ++ T  V D  V +W
Sbjct: 507 ASMDCTVRTWSLVHGRLIDCF-AVEAAVTSLTMSPSQDFLATSHVGDVGVYLW 662
>01768
          Length = 1424

 Score = 47.4 bits (111), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 32/129 (24%), Positives = 62/129 (48%), Gaps = 12/129 (9%)
 Frame = +3

Query: 145 TLKGHTDSVQDISFD-HSGKLLASCSADMTIKLWDFQG----FECIRTMHGHDHNVSSVA 199
           +   HTDSV+D+ +  + G + ASCS D T+++W+ Q        +     H  +++ + 
Sbjct: 822 SYAAHTDSVEDVQWSPNEGNVFASCSVDRTLRIWNTQQKPSKANVLTVPEAHSRDINVIN 1001

Query: 200 IMPNGDHIV-SASRDKTIKMWEV-----QTGYCVKTFTGHREWVRMVRPN-QDGTLIASC 252
             P   H++ S   D  IK+W++     +      +F  H + V  +  N QD +++A+ 
Sbjct: 1002WNPIEKHLLASGGDDGIIKIWDLRMFRNKPVSAQASFKLHSQPVTSLEWNPQDSSVLAAS 1181

Query: 253 SNDQTVRVW 261
             D  + +W
Sbjct: 1182GEDDQITIW 1208

 Score = 40.8 bits (94), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 29/103 (28%), Positives = 44/103 (42%), Gaps = 6/103 (5%)
 Frame = +3

Query: 229 TFTGHREWVRMVR--PNQDGTLIASCSNDQTVRVWVVATKECKAEL----REHEHVVECI 282
           ++  H + V  V+  PN+ G + ASCS D+T+R+W    K  KA +      H   +  I
Sbjct: 822 SYAAHTDSVEDVQWSPNE-GNVFASCSVDRTLRIWNTQQKPSKANVLTVPEAHSRDINVI 998

Query: 283 SWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDV 325
           +W P   +                    L SG  D  IK+WD+
Sbjct: 999 NWNPIEKH-------------------LLASGGDDGIIKIWDL 1070

 Score = 32.7 bits (73), Expect = 0.28,   Method: Compositional matrix adjust.
 Identities = 31/133 (23%), Positives = 62/133 (46%), Gaps = 11/133 (8%)
 Frame = +3

Query: 287 ESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDV----STGMCLMTLVGHDNWVR 342
           +SSY++ +++   + + S   G    S S D+T+++W+     S    L     H   + 
Sbjct: 816 KSSYAAHTDSV-EDVQWSPNEGNVFASCSVDRTLRIWNTQQKPSKANVLTVPEAHSRDIN 992

Query: 343 GVLFHSGGKFIL-SCADDKTLRVWD---YKNK--RCMKTLNAHEHFVTSLDFHKTAPYVV 396
            + ++   K +L S  DD  +++WD   ++NK      +   H   VTSL+++     V+
Sbjct: 993 VINWNPIEKHLLASGGDDGIIKIWDLRMFRNKPVSAQASFKLHSQPVTSLEWNPQDSSVL 1172

Query: 397 TGS-VDQTVKVWE 408
             S  D  + +W+
Sbjct: 1173AASGEDDQITIWD 1211

 Score = 28.5 bits (62), Expect = 5.7,   Method: Compositional matrix adjust.
 Identities = 17/58 (29%), Positives = 28/58 (48%), Gaps = 1/58 (1%)
 Frame = +3

Query: 107  HRSPVTRVIFHPV-FSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGK 163
            H  PVT + ++P   SV+ ++ ED  I +WD+     E   +   D    + F H G+
Sbjct: 1119 HSQPVTSLEWNPQDSSVLAASGEDDQITIWDFSVERDEGEGEEELDVPAQLLFQHCGQ 1292
>14555
          Length = 627

 Score = 37.4 bits (85), Expect(2) = 2e-05,   Method: Compositional matrix adjust.
 Identities = 17/50 (34%), Positives = 30/50 (60%), Gaps = 1/50 (2%)
 Frame = -3

Query: 171 DMTIKLWD-FQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMW 219
           D T+ +WD  +G      ++GHD+ VS + I P+G  + + S D T+++W
Sbjct: 403 DYTVNVWDALKGMR-STILYGHDNRVSCLRISPDGTSLCTGSWDYTLRIW 257

 Score = 28.5 bits (62), Expect(2) = 2e-05,   Method: Compositional matrix adjust.
 Identities = 10/33 (30%), Positives = 18/33 (54%)
 Frame = -2

Query: 104 LSGHRSPVTRVIFHPVFSVMVSASEDATIKVWD 136
             GH + +  V F+P      + S+DAT +++D
Sbjct: 611 FEGHEADINCVRFYPSGDAFATGSDDATCRLFD 513

 Score = 36.2 bits (82), Expect(2) = 2e-04,   Method: Compositional matrix adjust.
 Identities = 11/41 (26%), Positives = 25/41 (60%)
 Frame = -2

Query: 183 ECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQT 223
           EC++   GH+ +++ V   P+GD   + S D T ++++++ 
Sbjct: 626 ECVQMFEGHEADINCVRFYPSGDAFATGSDDATCRLFDLRA 504

 Score = 26.2 bits (56), Expect(2) = 2e-04,   Method: Compositional matrix adjust.
 Identities = 18/71 (25%), Positives = 28/71 (39%)
 Frame = -3

Query: 253 SNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSSISEATGSETKKSGKPGPFLL 312
           +ND TV VW          L  H++ V C+  +P+                    G  L 
Sbjct: 409 TNDYTVNVWDALKGMRSTILYGHDNRVSCLRISPD--------------------GTSLC 290

Query: 313 SGSRDKTIKMW 323
           +GS D T+++W
Sbjct: 289 TGSWDYTLRIW 257

 Score = 36.2 bits (82), Expect = 0.025,   Method: Compositional matrix adjust.
 Identities = 19/63 (30%), Positives = 28/63 (44%)
 Frame = -3

Query: 115 IFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSADMTI 174
           IF  V    +  + D T+ VWD   G     L GH + V  +     G  L + S D T+
Sbjct: 445 IFLSVVDCCLGVTNDYTVNVWDALKGMRSTILYGHDNRVSCLRISPDGTSLCTGSWDYTL 266

Query: 175 KLW 177
           ++W
Sbjct: 265 RIW 257

 Score = 34.3 bits (77), Expect = 0.083,   Method: Compositional matrix adjust.
 Identities = 19/54 (35%), Positives = 27/54 (50%)
 Frame = -3

Query: 312 LSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVW 365
           L  + D T+ +WD   GM    L GHDN V  +     G  + + + D TLR+W
Sbjct: 418 LGVTNDYTVNVWDALKGMRSTILYGHDNRVSCLRISPDGTSLCTGSWDYTLRIW 257

 Score = 33.9 bits (76), Expect = 0.11,   Method: Compositional matrix adjust.
 Identities = 17/57 (29%), Positives = 28/57 (49%)
 Frame = -3

Query: 205 DHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVW 261
           D  +  + D T+ +W+   G       GH   V  +R + DGT + + S D T+R+W
Sbjct: 427 DCCLGVTNDYTVNVWDALKGMRSTILYGHDNRVSCLRISPDGTSLCTGSWDYTLRIW 257

 Score = 31.2 bits (69), Expect = 0.89,   Method: Compositional matrix adjust.
 Identities = 18/63 (28%), Positives = 28/63 (44%)
 Frame = -3

Query: 345 LFHSGGKFILSCADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTV 404
           +F S     L   +D T+ VWD         L  H++ V+ L        + TGS D T+
Sbjct: 445 IFLSVVDCCLGVTNDYTVNVWDALKGMRSTILYGHDNRVSCLRISPDGTSLCTGSWDYTL 266

Query: 405 KVW 407
           ++W
Sbjct: 265 RIW 257
>15780
          Length = 735

 Score = 46.2 bits (108), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 22/57 (38%), Positives = 31/57 (54%)
 Frame = -1

Query: 123 MVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDF 179
           + +A  D T+ VWD  +G     L  HTD+V  + F   G +LAS   D +I+LWD 
Sbjct: 729 LSTAGADHTVIVWDIASGTAVAHLTAHTDTVYALCFSRDGTVLASGGMDNSIRLWDL 559

 Score = 43.1 bits (100), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 18/59 (30%), Positives = 36/59 (61%)
 Frame = -1

Query: 206 HIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVA 264
           ++ +A  D T+ +W++ +G  V   T H + V  +  ++DGT++AS   D ++R+W +A
Sbjct: 732 YLSTAGADHTVIVWDIASGTAVAHLTAHTDTVYALCFSRDGTVLASGGMDNSIRLWDLA 556
>15337
          Length = 860

 Score = 46.2 bits (108), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 22/91 (24%), Positives = 42/91 (46%)
 Frame = -1

Query: 150 TDSVQDISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVS 209
           T ++ + +F    + LA    D  ++++++   E I TM  +   +  V   P+G +IV+
Sbjct: 329 TGAISEFAFSPCSRYLAVVGQDGHLRVFNYNSMELIGTMKSYFGGLLCVCWSPDGKYIVT 150

Query: 210 ASRDKTIKMWEVQTGYCVKTFTGHREWVRMV 240
              D  + +W       V    GH+ WV +V
Sbjct: 149 GGEDDLVTVWSFHEKRVVCRGHGHKSWVNVV 57

 Score = 36.2 bits (82), Expect = 0.023,   Method: Compositional matrix adjust.
 Identities = 18/90 (20%), Positives = 39/90 (43%)
 Frame = -1

Query: 111 VTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSA 170
           ++   F P    +    +D  ++V++Y + +   T+K +   +  + +   GK + +   
Sbjct: 320 ISEFAFSPCSRYLAVVGQDGHLRVFNYNSMELIGTMKSYFGGLLCVCWSPDGKYIVTGGE 141

Query: 171 DMTIKLWDFQGFECIRTMHGHDHNVSSVAI 200
           D  + +W F     +   HGH   V+ VA 
Sbjct: 140 DDLVTVWSFHEKRVVCRGHGHKSWVNVVAF 51

 Score = 31.2 bits (69), Expect = 0.88,   Method: Compositional matrix adjust.
 Identities = 15/62 (24%), Positives = 29/62 (46%)
 Frame = -1

Query: 346 FHSGGKFILSCADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVK 405
           F    +++     D  LRV++Y +   + T+ ++   +  + +     Y+VTG  D  V 
Sbjct: 305 FSPCSRYLAVVGQDGHLRVFNYNSMELIGTMKSYFGGLLCVCWSPDGKYIVTGGEDDLVT 126

Query: 406 VW 407
           VW
Sbjct: 125 VW 120

 Score = 28.9 bits (63), Expect = 4.4,   Method: Compositional matrix adjust.
 Identities = 18/98 (18%), Positives = 37/98 (37%)
 Frame = -1

Query: 249 IASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSSISEATGSETKKSGKPG 308
           +A    D  +RV+   + E    ++ +   + C+ W+P+                    G
Sbjct: 284 LAVVGQDGHLRVFNYNSMELIGTMKSYFGGLLCVCWSPD--------------------G 165

Query: 309 PFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLF 346
            ++++G  D  + +W       +    GH +WV  V F
Sbjct: 164 KYIVTGGEDDLVTVWSFHEKRVVCRGHGHKSWVNVVAF 51

 Score = 28.5 bits (62), Expect = 4.5,   Method: Compositional matrix adjust.
 Identities = 15/79 (18%), Positives = 40/79 (50%)
 Frame = -1

Query: 310 FLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKN 369
           +L    +D  +++++ ++   + T+  +   +  V +   GK+I++  +D  + VW +  
Sbjct: 287 YLAVVGQDGHLRVFNYNSMELIGTMKSYFGGLLCVCWSPDGKYIVTGGEDDLVTVWSFHE 108

Query: 370 KRCMKTLNAHEHFVTSLDF 388
           KR +   + H+ +V  + F
Sbjct: 107 KRVVCRGHGHKSWVNVVAF 51
>19140
          Length = 573

 Score = 45.1 bits (105), Expect = 6e-05,   Method: Compositional matrix adjust.
 Identities = 22/74 (29%), Positives = 39/74 (52%)
 Frame = -3

Query: 331 LMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFHK 390
           LM L GH + V+ ++ +  G   LS + D T+R+W    +RC+ T   H+  V +L  ++
Sbjct: 508 LMKLKGHTDNVKALVLNRDGTQCLSGSSDGTIRLWSLGQQRCVATFRVHDEGVWALQANE 329

Query: 391 TAPYVVTGSVDQTV 404
           +   + +G  D  V
Sbjct: 328 SFTTLYSGGRDHQV 287

 Score = 44.3 bits (103), Expect = 9e-05,   Method: Compositional matrix adjust.
 Identities = 25/80 (31%), Positives = 39/80 (48%)
 Frame = -3

Query: 188 MHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGT 247
           + GH  NV ++ +  +G   +S S D TI++W +    CV TF  H E V  ++ N+  T
Sbjct: 499 LKGHTDNVKALVLNRDGTQCLSGSSDGTIRLWSLGQQRCVATFRVHDEGVWALQANESFT 320

Query: 248 LIASCSNDQTVRVWVVATKE 267
            + S   D   +VW    K 
Sbjct: 319 TLYSGGRDH--QVWATDIKN 266

 Score = 43.9 bits (102), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 23/71 (32%), Positives = 35/71 (49%)
 Frame = -3

Query: 146 LKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGD 205
           LKGHTD+V+ +  +  G    S S+D TI+LW      C+ T   HD  V ++    +  
Sbjct: 499 LKGHTDNVKALVLNRDGTQCLSGSSDGTIRLWSLGQQRCVATFRVHDEGVWALQANESFT 320

Query: 206 HIVSASRDKTI 216
            + S  RD  +
Sbjct: 319 TLYSGGRDHQV 287

 Score = 38.9 bits (89), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 22/69 (31%), Positives = 37/69 (53%)
 Frame = -3

Query: 230 FTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESS 289
             GH + V+ +  N+DGT   S S+D T+R+W +  + C A  R H+  V    WA +++
Sbjct: 499 LKGHTDNVKALVLNRDGTQCLSGSSDGTIRLWSLGQQRCVATFRVHDEGV----WALQAN 332

Query: 290 YSSISEATG 298
            S  +  +G
Sbjct: 331 ESFTTLYSG 305

 Score = 36.6 bits (83), Expect = 0.018,   Method: Compositional matrix adjust.
 Identities = 27/104 (25%), Positives = 42/104 (40%), Gaps = 1/104 (0%)
 Frame = -3

Query: 308 GPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDY 367
           G   LSGS D TI++W +    C+ T   HD  V  +  +     + S   D  +   D 
Sbjct: 451 GTQCLSGSSDGTIRLWSLGQQRCVATFRVHDEGVWALQANESFTTLYSGGRDHQVWATDI 272

Query: 368 KNKRCMKTLNAHEHFVTSLDFHKTAPYVV-TGSVDQTVKVWECR 410
           KN    + +   +  V  L+   T P  +   + D  +K W  R
Sbjct: 271 KNPDNRELICEEKAPVLKLELTPTDPPSLWVATTDSCIKNWPVR 140

 Score = 29.6 bits (65), Expect = 2.4,   Method: Compositional matrix adjust.
 Identities = 32/156 (20%), Positives = 53/156 (33%), Gaps = 13/156 (8%)
 Frame = -3

Query: 104 LSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGK 163
           L GH   V  ++ +   +  +S S D TI++W         T + H + V          
Sbjct: 499 LKGHTDNVKALVLNRDGTQCLSGSSDGTIRLWSLGQQRCVATFRVHDEGV---------- 350

Query: 164 LLASCSADMTIKLWDFQGFECIRTMH--GHDHNVSSVAIM-PNGDHIVSASRDKTIK--- 217
                        W  Q  E   T++  G DH V +  I  P+   ++   +   +K   
Sbjct: 349 -------------WALQANESFTTLYSGGRDHQVWATDIKNPDNRELICEEKAPVLKLEL 209

Query: 218 -------MWEVQTGYCVKTFTGHREWVRMVRPNQDG 246
                  +W   T  C+K +      VR+  P   G
Sbjct: 208 TPTDPPSLWVATTDSCIKNWP-----VRLPNPRASG 116
>01249
          Length = 1743

 Score = 43.9 bits (102), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 45/207 (21%), Positives = 78/207 (37%), Gaps = 13/207 (6%)
 Frame = -1

Query: 215  TIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELRE 274
            ++  W++Q+   V+TF G       +      TL+ +  N   + VW ++ K+      E
Sbjct: 1674 SVAAWDIQSRSSVRTFKGQALAAGCLCLRCGHTLLGAAQNKPVIHVWPLSKKD------E 1513

Query: 275  HEHVVECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTL 334
             +H + C                G  +     P       S  + I +W++ TG  L+ L
Sbjct: 1512 SQHKIVC---------------PGKVSVLVVSPDGLFCLASISEKIYIWEM-TGGSLVGL 1381

Query: 335  VGHDNWVRGVLFHSGGKFILSCADDKTLRVWDY--------KNKRCMK---TLNAHEHFV 383
            +   N    + F   G   +       L +WD+        +  R +K   T+NAH   +
Sbjct: 1380 LSDFNEATKIQFTDDGSQFVVATSSGHLNIWDFARVVTTTSQRARGLKPGRTINAHSEPI 1201

Query: 384  TSLDFHKTAPY--VVTGSVDQTVKVWE 408
            T L      P   V + S D T K+W+
Sbjct: 1200 TGLHVGCGGPAARVASSSSDGTCKLWD 1120

 Score = 36.2 bits (82), Expect = 0.024,   Method: Compositional matrix adjust.
 Identities = 21/67 (31%), Positives = 38/67 (56%)
 Frame = -1

Query: 114  VIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSADMT 173
            ++  P+F   +S SE   + V  + T   ER L+GH+D+V  ++F   G+ LAS S +  
Sbjct: 1011 ILCSPLFG-QISQSE---VFVSKHTTKAGERVLQGHSDAVTCLAFSSDGQRLASGSQNGK 844

Query: 174  IKLWDFQ 180
            + +W+ +
Sbjct: 843  VIIWNME 823

 Score = 35.8 bits (81), Expect = 0.029,   Method: Compositional matrix adjust.
 Identities = 44/178 (24%), Positives = 71/178 (39%), Gaps = 28/178 (15%)
 Frame = -1

Query: 112  TRVIFHPVFSVMVSASEDATIKVWDYE---TGDFER--------TLKGHTDSVQDISFDH 160
            T++ F    S  V A+    + +WD+    T   +R        T+  H++ +  +    
Sbjct: 1359 TKIQFTDDGSQFVVATSSGHLNIWDFARVVTTTSQRARGLKPGRTINAHSEPITGLHVGC 1180

Query: 161  SGKL--LASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDK---- 214
             G    +AS S+D T KLWD      +RTM  ++  V  + IM   +H + A  D     
Sbjct: 1179 GGPAARVASSSSDGTCKLWDMLSGALLRTMV-YETGVGCL-IMDKQEHFLLAGLDNGDIL 1006

Query: 215  ------TIKMWEV-----QTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVW 261
                   I   EV      T    +   GH + V  +  + DG  +AS S +  V +W
Sbjct: 1005 CSPLFGQISQSEVFVSKHTTKAGERVLQGHSDAVTCLAFSSDGQRLASGSQNGKVIIW 832

 Score = 28.1 bits (61), Expect = 6.1,   Method: Compositional matrix adjust.
 Identities = 12/38 (31%), Positives = 20/38 (52%)
 Frame = -1

Query: 104 LSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGD 141
           L GH   VT + F      + S S++  + +W+ E+GD
Sbjct: 927 LQGHSDAVTCLAFSSDGQRLASGSQNGKVIIWNMESGD 814
>11493
          Length = 535

 Score = 43.5 bits (101), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 23/109 (21%), Positives = 43/109 (39%), Gaps = 2/109 (1%)
 Frame = -2

Query: 111 VTRVIFHPVFSVMVSASEDATIKVWDY--ETGDFERTLKGHTDSVQDISFDHSGKLLASC 168
           +  V   P    ++   E + + +WD    T   +  L     +   ++     K+  SC
Sbjct: 330 IRSVKLLPDGRTLIVGGEASNLSIWDLASPTPRIKAELTSAAPACYALAISPDSKVCFSC 151

Query: 169 SADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIK 217
            +D  I +WD      +R   GH    S + I P+G  + +   D T++
Sbjct: 150 CSDGNIAVWDLHNEILVRQFQGHTDGASCIDISPDGSRLWTGGLDNTVR 4

 Score = 35.8 bits (81), Expect = 0.028,   Method: Compositional matrix adjust.
 Identities = 22/100 (22%), Positives = 37/100 (37%), Gaps = 2/100 (2%)
 Frame = -2

Query: 308 GPFLLSGSRDKTIKMWDVS--TGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVW 365
           G  L+ G     + +WD++  T      L         +      K   SC  D  + VW
Sbjct: 303 GRTLIVGGEASNLSIWDLASPTPRIKAELTSAAPACYALAISPDSKVCFSCCSDGNIAVW 124

Query: 366 DYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVK 405
           D  N+  ++    H    + +D       + TG +D TV+
Sbjct: 123 DLHNEILVRQFQGHTDGASCIDISPDGSRLWTGGLDNTVR 4

 Score = 35.4 bits (80), Expect = 0.040,   Method: Compositional matrix adjust.
 Identities = 22/80 (27%), Positives = 28/80 (35%)
 Frame = -2

Query: 96  PRPPEKYALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQD 155
           P P  K  L+        +   P   V  S   D  I VWD       R  +GHTD    
Sbjct: 243 PTPRIKAELTSAAPACYALAISPDSKVCFSCCSDGNIAVWDLHNEILVRQFQGHTDGASC 64

Query: 156 ISFDHSGKLLASCSADMTIK 175
           I     G  L +   D T++
Sbjct: 63  IDISPDGSRLWTGGLDNTVR 4

 Score = 33.1 bits (74), Expect = 0.23,   Method: Compositional matrix adjust.
 Identities = 17/63 (26%), Positives = 30/63 (47%)
 Frame = -2

Query: 197 SVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQ 256
           ++AI P+     S   D  I +W++     V+ F GH +    +  + DG+ + +   D 
Sbjct: 192 ALAISPDSKVCFSCCSDGNIAVWDLHNEILVRQFQGHTDGASCIDISPDGSRLWTGGLDN 13

Query: 257 TVR 259
           TVR
Sbjct: 12  TVR 4

 Score = 32.7 bits (73), Expect = 0.28,   Method: Compositional matrix adjust.
 Identities = 23/127 (18%), Positives = 50/127 (39%), Gaps = 11/127 (8%)
 Frame = -2

Query: 174 IKLWDFQG---------FECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQ-- 222
           +K+WD             +C++     D+ + SV ++P+G  ++       + +W++   
Sbjct: 408 VKVWDISQPGNKNPVSQLDCLQ----RDNYIRSVKLLPDGRTLIVGGEASNLSIWDLASP 241

Query: 223 TGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECI 282
           T       T        +  + D  +  SC +D  + VW +  +    + + H     CI
Sbjct: 240 TPRIKAELTSAAPACYALAISPDSKVCFSCCSDGNIAVWDLHNEILVRQFQGHTDGASCI 61

Query: 283 SWAPESS 289
             +P+ S
Sbjct: 60  DISPDGS 40

 Score = 28.5 bits (62), Expect = 4.9,   Method: Compositional matrix adjust.
 Identities = 20/110 (18%), Positives = 44/110 (40%), Gaps = 7/110 (6%)
 Frame = -2

Query: 306 KPGPFLLSGSRDKTIKMWDVS-----TGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDK 360
            P  ++ +G +   +K+WD+S       +  +  +  DN++R V     G+ ++   +  
Sbjct: 447 NPTKYVYTGGK-GCVKVWDISQPGNKNPVSQLDCLQRDNYIRSVKLLPDGRTLIVGGEAS 271

Query: 361 TLRVWDYKN--KRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWE 408
            L +WD  +   R    L +      +L     +    +   D  + VW+
Sbjct: 270 NLSIWDLASPTPRIKAELTSAAPACYALAISPDSKVCFSCCSDGNIAVWD 121
>01462
          Length = 995

 Score = 43.1 bits (100), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 17/59 (28%), Positives = 36/59 (61%)
 Frame = +2

Query: 311 LLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKN 369
           L +G+ D+ I +WD+  G  L  + GH +++  V+  +  +  +S ++D T+R+WD ++
Sbjct: 242 LYAGAGDRKIHVWDIEAGQYLNAMEGHKDYIHKVVMKNDAQECVSASEDGTVRMWDIRS 418

 Score = 41.6 bits (96), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 16/58 (27%), Positives = 30/58 (51%)
 Frame = +2

Query: 123 MVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQ 180
           + + + D  I VWD E G +   ++GH D +  +   +  +   S S D T+++WD +
Sbjct: 242 LYAGAGDRKIHVWDIEAGQYLNAMEGHKDYIHKVVMKNDAQECVSASEDGTVRMWDIR 415

 Score = 40.4 bits (93), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 17/59 (28%), Positives = 32/59 (54%)
 Frame = +2

Query: 165 LASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQT 223
           L + + D  I +WD +  + +  M GH   +  V +  +    VSAS D T++MW++++
Sbjct: 242 LYAGAGDRKIHVWDIEAGQYLNAMEGHKDYIHKVVMKNDAQECVSASEDGTVRMWDIRS 418

 Score = 38.1 bits (87), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 18/76 (23%), Positives = 35/76 (46%)
 Frame = +2

Query: 207 IVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATK 266
           + + + D+ I +W+++ G  +    GH++++  V    D     S S D TVR+W     
Sbjct: 242 LYAGAGDRKIHVWDIEAGQYLNAMEGHKDYIHKVVMKNDAQECVSASEDGTVRMW----- 406

Query: 267 ECKAELREHEHVVECI 282
               ++R     V C+
Sbjct: 407 ----DIRSSTETVHCL 442

 Score = 30.0 bits (66), Expect = 1.7,   Method: Compositional matrix adjust.
 Identities = 13/37 (35%), Positives = 22/37 (59%)
 Frame = +2

Query: 103 ALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYET 139
           A+ GH+  + +V+        VSASED T+++WD  +
Sbjct: 308 AMEGHKDYIHKVVMKNDAQECVSASEDGTVRMWDIRS 418
>00825
          Length = 1821

 Score = 42.7 bits (99), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 32/102 (31%), Positives = 48/102 (47%), Gaps = 6/102 (5%)
 Frame = -2

Query: 313  SGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNKRC 372
            SG+ D  +  W++        +  HD  V G+  HS G++  SC  DKT++ W    +  
Sbjct: 1820 SGACDGELICWNLPKQQMACRVQAHDGIVHGMAAHSSGQYFFSCGSDKTIKQWSLDPEGT 1641

Query: 373  M-----KTLNAHEHFVTSLDFH-KTAPYVVTGSVDQTVKVWE 408
            +      TL A +   TSLD H K   +V +GS    V VW+
Sbjct: 1640 IAPEPVNTLLA-KCIYTSLDHHWKDDIFVTSGS---RVDVWD 1527

 Score = 35.4 bits (80), Expect = 0.042,   Method: Compositional matrix adjust.
 Identities = 59/284 (20%), Positives = 110/284 (38%), Gaps = 43/284 (15%)
 Frame = -2

Query: 125  SASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLW--DFQGF 182
            S + D  +  W+         ++ H   V  ++   SG+   SC +D TIK W  D +G 
Sbjct: 1820 SGACDGELICWNLPKQQMACRVQAHDGIVHGMAAHSSGQYFFSCGSDKTIKQWSLDPEGT 1641

Query: 183  ECIRTMHGHDHNVSSVAIMPNGDH-------IVSASRDKTIKMWEVQTGYCVKTFTGHRE 235
                 +    + + +  I  + DH       + S SR   + +W+ +    +++F+   E
Sbjct: 1640 IAPEPV----NTLLAKCIYTSLDHHWKDDIFVTSGSR---VDVWDEKRSEPMRSFSWGVE 1482

Query: 236  WVRMVRPNQDGT-LIASCSNDQTVRVWVVATKECKAELRE--HEHVVECISWAPESSYSS 292
             V  V+ N   T L+ + ++D+++ ++ +      A LR+   +     +SW P  +++ 
Sbjct: 1481 SVHHVKFNPVETYLLGAAAHDRSILLYDM---RGSAPLRKVVMKMRTNALSWNPMEAFTI 1311

Query: 293  ISEATGS-----ETKKSGKP-------------------GPFLLSGSRDKTIKMWDVSTG 328
             S          + +K   P                   G   +S   DK I+++ V  G
Sbjct: 1310 TSANEDGNLYTFDMRKLSMPLNMHRDHTAAVMDVDYCPTGREFVSAGYDKVIRIFPVDKG 1131

Query: 329  MC-------LMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVW 365
                      M  VG   W R        K+I S +D+  +RVW
Sbjct: 1130 HSREVYHTKRMQRVGSVVWSR------DSKYIFSASDEMNIRVW 1017

 Score = 32.0 bits (71), Expect = 0.44,   Method: Compositional matrix adjust.
 Identities = 23/101 (22%), Positives = 43/101 (42%), Gaps = 2/101 (1%)
 Frame = -2

Query: 123  MVSASEDATIKVWDYETGDFERTL-KGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQG 181
            + SA+ED  +  +D         + + HT +V D+ +  +G+   S   D  I+++    
Sbjct: 1313 ITSANEDGNLYTFDMRKLSMPLNMHRDHTAAVMDVDYCPTGREFVSAGYDKVIRIFPVDK 1134

Query: 182  FECIRTMHGHD-HNVSSVAIMPNGDHIVSASRDKTIKMWEV 221
                   H      V SV    +  +I SAS +  I++W+ 
Sbjct: 1133 GHSREVYHTKRMQRVGSVVWSRDSKYIFSASDEMNIRVWKA 1011
>30176
          Length = 365

 Score = 42.7 bits (99), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 19/33 (57%), Positives = 25/33 (75%)
 Frame = +2

Query: 145 TLKGHTDSVQDISFDHSGKLLASCSADMTIKLW 177
           TLK HT +V +++FD +G  LASCS D TIK+W
Sbjct: 5   TLKSHTSTVWNLTFDKTGTRLASCSDDKTIKIW 103

 Score = 29.6 bits (65), Expect = 2.1,   Method: Compositional matrix adjust.
 Identities = 13/33 (39%), Positives = 20/33 (60%)
 Frame = +2

Query: 333 TLVGHDNWVRGVLFHSGGKFILSCADDKTLRVW 365
           TL  H + V  + F   G  + SC+DDKT+++W
Sbjct: 5   TLKSHTSTVWNLTFDKTGTRLASCSDDKTIKIW 103

 Score = 28.9 bits (63), Expect = 3.6,   Method: Compositional matrix adjust.
 Identities = 12/33 (36%), Positives = 21/33 (63%)
 Frame = +2

Query: 229 TFTGHREWVRMVRPNQDGTLIASCSNDQTVRVW 261
           T   H   V  +  ++ GT +ASCS+D+T+++W
Sbjct: 5   TLKSHTSTVWNLTFDKTGTRLASCSDDKTIKIW 103

 Score = 28.9 bits (63), Expect = 4.2,   Method: Compositional matrix adjust.
 Identities = 13/34 (38%), Positives = 21/34 (61%)
 Frame = +2

Query: 375 TLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWE 408
           TL +H   V +L F KT   + + S D+T+K+W+
Sbjct: 5   TLKSHTSTVWNLTFDKTGTRLASCSDDKTIKIWQ 106

 Score = 28.5 bits (62), Expect = 5.2,   Method: Compositional matrix adjust.
 Identities = 26/94 (27%), Positives = 39/94 (41%), Gaps = 24/94 (25%)
 Frame = +2

Query: 103 ALSGHRSPVTRVIFHPVFSVMVSASEDATIKVW-DYETGDFER--------------TLK 147
            L  H S V  + F    + + S S+D TIK+W +Y  G+ E               TL 
Sbjct: 5   TLKSHTSTVWNLTFDKTGTRLASCSDDKTIKIWQEYLPGNPEGIVTKDNEPTWKCVCTLG 184

Query: 148 GHTD-SVQDISFDH--------SGKLLASCSADM 172
           G+T  ++ DI + H         G +L +C   M
Sbjct: 185 GYTSRALYDIDWSHLTGDIVTAGGMILFACFGKM 286
>21921
          Length = 1341

 Score = 42.0 bits (97), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 21/55 (38%), Positives = 29/55 (52%), Gaps = 2/55 (3%)
 Frame = -1

Query: 178 DFQGFECIRTM--HGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTF 230
           D + F   + +   GH   V S+   P G  +VS S D TI+ WEV +G C+KT 
Sbjct: 531 DLRPFPTTQALVYKGHTGIVRSICPDPTGQWLVSGSDDGTIRFWEVSSGRCMKTL 367

 Score = 41.6 bits (96), Expect = 6e-04,   Method: Compositional matrix adjust.
 Identities = 26/73 (35%), Positives = 41/73 (56%), Gaps = 1/73 (1%)
 Frame = -1

Query: 147 KGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDH 206
           KGHT  V+ I  D +G+ L S S D TI+ W+     C++T+      V+SVA  PN   
Sbjct: 492 KGHTGIVRSICPDPTGQWLVSGSDDGTIRFWEVSSGRCMKTLQV-GGCVTSVAWNPNPSL 316

Query: 207 -IVSASRDKTIKM 218
            +V+A+ + T+ +
Sbjct: 315 CVVAATLNTTVLL 277

 Score = 40.8 bits (94), Expect = 9e-04,   Method: Compositional matrix adjust.
 Identities = 24/70 (34%), Positives = 39/70 (55%), Gaps = 1/70 (1%)
 Frame = -1

Query: 336 GHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPY- 394
           GH   VR +     G++++S +DD T+R W+  + RCMKTL      VTS+ ++      
Sbjct: 489 GHTGIVRSICPDPTGQWLVSGSDDGTIRFWEVSSGRCMKTLQVG-GCVTSVAWNPNPSLC 313

Query: 395 VVTGSVDQTV 404
           VV  +++ TV
Sbjct: 312 VVAATLNTTV 283

 Score = 37.4 bits (85), Expect = 0.013,   Method: Compositional matrix adjust.
 Identities = 24/80 (30%), Positives = 38/80 (47%)
 Frame = -1

Query: 229 TFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPES 288
            + GH   VR + P+  G  + S S+D T+R W V++  C   L +    V  ++W P  
Sbjct: 498 VYKGHTGIVRSICPDPTGQWLVSGSDDGTIRFWEVSSGRCMKTL-QVGGCVTSVAWNPNP 322

Query: 289 SYSSISEATGSETKKSGKPG 308
           S   ++ AT + T     PG
Sbjct: 321 SLCVVA-ATLNTTVLLINPG 265

 Score = 35.4 bits (80), Expect = 0.037,   Method: Compositional matrix adjust.
 Identities = 15/27 (55%), Positives = 21/27 (77%)
 Frame = -1

Query: 308 GPFLLSGSRDKTIKMWDVSTGMCLMTL 334
           G +L+SGS D TI+ W+VS+G C+ TL
Sbjct: 447 GQWLVSGSDDGTIRFWEVSSGRCMKTL 367
>26107
          Length = 1338

 Score = 42.0 bits (97), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 41/154 (26%), Positives = 68/154 (44%), Gaps = 19/154 (12%)
 Frame = -3

Query: 190  GHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVR--PNQDGT 247
             H++ V   + + N    ++AS D+T+ +W+V+T   V TF GH+  VR V   P+    
Sbjct: 1093 AHNNAVFDYSWISNDSQCLTASGDQTVALWDVETTTKVTTFIGHKCSVRSVASCPSSPAQ 914

Query: 248  LIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSS-------ISEATGS- 299
              AS + D  + +W         + REH+   +     P+S + S       I  A G  
Sbjct: 913  C-ASGARDGHIMLWDSRVN----KKREHQPCSQVHQVCPQSGHQSKPAKHRRIHRAAGPK 749

Query: 300  ---ETKKS------GKPGPFLLSGSRDKTIKMWD 324
               +T++S            + SG+ D  +KMWD
Sbjct: 748  GVMDTQQSVTCVLYQTDNLIISSGANDGCVKMWD 647

 Score = 39.3 bits (90), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 69/318 (21%), Positives = 121/318 (38%), Gaps = 57/318 (17%)
 Frame = -3

Query: 148  GHTDSVQDISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGD-H 206
             H ++V D S+  +     + S D T+ LWD +    + T  GH  +V SVA  P+    
Sbjct: 1093 AHNNAVFDYSWISNDSQCLTASGDQTVALWDVETTTKVTTFIGHKCSVRSVASCPSSPAQ 914

Query: 207  IVSASRDKTIKMWEV-------------------QTGYCVKTFTGHREWVRMVRP----- 242
              S +RD  I +W+                    Q+G+  K    HR   R   P     
Sbjct: 913  CASGARDGHIMLWDSRVNKKREHQPCSQVHQVCPQSGHQSKP-AKHRRIHRAAGPKGVMD 737

Query: 243  ----------NQDGTLIASCSNDQTVRVW---------------VVATKECKAELREHEH 277
                        D  +I+S +ND  V++W                V T +    +R  + 
Sbjct: 736  TQQSVTCVLYQTDNLIISSGANDGCVKMWDTRKWYTNTTTSLPVPVHTFDYPGHMRRLKG 557

Query: 278  VVE-CISWAPESSYSSISEATGSETKKSGK---PGPFLLSGSRDKTIKMWDVSTGMCLMT 333
            +V  C+       + S ++      + +G+   P  ++ +G R+ T              
Sbjct: 556  IVTMCMDPWKSQLFVSYTDNKVYRYQLAGQYREPQEYVYAGHRNDTF------------- 416

Query: 334  LVGHDNWVRGVLFHSGGKFILSCADDKTLRVW--DYKNKRCMKTLNAHEHFVTSLDFHKT 391
                  +VR  +    GK++LS +   T  +W  D  NKR +  L  H   V+++D+  T
Sbjct: 415  ------FVRCAI-SPDGKYLLSGSGRNTGVIWEVDKPNKRPL-FLIGHTEDVSAVDWCST 260

Query: 392  -APYVVTGSVDQTVKVWE 408
                + T S D+++++W 
Sbjct: 259  DVCKLATVSDDRSLRIWR 206

 Score = 35.4 bits (80), Expect = 0.038,   Method: Compositional matrix adjust.
 Identities = 44/186 (23%), Positives = 75/186 (40%), Gaps = 29/186 (15%)
 Frame = -3

Query: 111 VTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDI-----SFDHSGKLL 165
           VT V++     ++ S + D  +K+WD        T K +T++   +     +FD+ G + 
Sbjct: 724 VTCVLYQTDNLIISSGANDGCVKMWD--------TRKWYTNTTTSLPVPVHTFDYPGHMR 569

Query: 166 -ASCSADMTIKLWDFQGF---------------------ECIRTMHGHDHNVSSVAIMPN 203
                  M +  W  Q F                     E +   H +D      AI P+
Sbjct: 568 RLKGIVTMCMDPWKSQLFVSYTDNKVYRYQLAGQYREPQEYVYAGHRNDTFFVRCAISPD 389

Query: 204 GDHIVSASRDKTIKMWEVQTGYCVKTF-TGHREWVRMVR-PNQDGTLIASCSNDQTVRVW 261
           G +++S S   T  +WEV        F  GH E V  V   + D   +A+ S+D+++R+W
Sbjct: 388 GKYLLSGSGRNTGVIWEVDKPNKRPLFLIGHTEDVSAVDWCSTDVCKLATVSDDRSLRIW 209

Query: 262 VVATKE 267
               +E
Sbjct: 208 RPDARE 191
>20662
          Length = 1220

 Score = 42.0 bits (97), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 42/174 (24%), Positives = 67/174 (38%), Gaps = 19/174 (10%)
 Frame = +2

Query: 134 VWDYETGDFERTLKGHTDSVQ------DISFDHSGKLLASCSADMTIKLWDFQG----FE 183
           +W Y   D    +   T  VQ      D ++  S K+L        + LW+ Q     F 
Sbjct: 185 LWYYTNPDLAPNVDKCTAGVQLEAGLRDAAWVDSHKVLVGLDTG-GVALWELQDEDKMFS 361

Query: 184 CIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHRE--WVRMVR 241
            + +   HD   +SV+I  +  H +SAS D  IK+W       + T+  H +  W     
Sbjct: 362 MLSSACEHDDMTASVSINSDXSHYLSASYDHGIKVWNTDL-TSLYTYRAHSDIVWDVQCH 538

Query: 242 PNQDGTLIASCSNDQTVRVWVV-------ATKECKAELREHEHVVECISWAPES 288
           P +   L  SCS D  + +W V          +C +  +       C+ W P +
Sbjct: 539 PTEPA-LFLSCSQDGKIVLWDVRESKPATCLPKCSSGFKP-----TCVQWQPNA 682

 Score = 29.6 bits (65), Expect = 2.1,   Method: Compositional matrix adjust.
 Identities = 20/75 (26%), Positives = 35/75 (46%), Gaps = 1/75 (1%)
 Frame = +2

Query: 337 HDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYV- 395
           HD+    V  +S     LS + D  ++VW+  +   + T  AH   V  +  H T P + 
Sbjct: 383 HDDMTASVSINSDXSHYLSASYDHGIKVWN-TDLTSLYTYRAHSDIVWDVQCHPTEPALF 559

Query: 396 VTGSVDQTVKVWECR 410
           ++ S D  + +W+ R
Sbjct: 560 LSCSQDGKIVLWDVR 604

 Score = 28.1 bits (61), Expect = 6.6,   Method: Compositional matrix adjust.
 Identities = 19/61 (31%), Positives = 28/61 (45%), Gaps = 1/61 (1%)
 Frame = +2

Query: 312 LSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFH-SGGKFILSCADDKTLRVWDYKNK 370
           LS S D  IK+W+      L T   H + V  V  H +     LSC+ D  + +WD +  
Sbjct: 434 LSASYDHGIKVWNTDL-TSLYTYRAHSDIVWDVQCHPTEPALFLSCSQDGKIVLWDVRES 610

Query: 371 R 371
           +
Sbjct: 611 K 613
>15745
          Length = 1183

 Score = 40.4 bits (93), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 47/201 (23%), Positives = 77/201 (38%), Gaps = 5/201 (2%)
 Frame = +2

Query: 188 MHGHDHNVSSVAIMPNGDH--IVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQD 245
           +H  DH+V  +   P GD   ++    D+ I MW++                        
Sbjct: 416 LHSSDHDVKGILWHPTGDSQTVLGVCEDRVI-MWDLN----------------------- 523

Query: 246 GTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSSISEATGSETKKSG 305
              +AS S  QT  +    T E K + R     + C  W P  + + I+ A         
Sbjct: 524 ---VASSSAQQTDMI----TLEGKGQPR-----LTCGRWNPHHNCAQIATAN-------- 643

Query: 306 KPGPFLLSGSRDKTIKMWDVSTGMCLMTLVG-HDNWVRGVLFHSGGKFIL-SCADDKTLR 363
                      + TI+ WD+ +      + G H   VR + F+   ++ L SC DD  ++
Sbjct: 644 -----------EATIRGWDLRSKQQTYQMEGAHGQLVRDLDFNPNRQYYLASCGDDCRVK 790

Query: 364 VWDYKN-KRCMKTLNAHEHFV 383
            WD +N    +K L+ H H+V
Sbjct: 791 FWDTRNCSEPLKVLSDHSHWV 853

 Score = 35.8 bits (81), Expect = 0.029,   Method: Compositional matrix adjust.
 Identities = 21/75 (28%), Positives = 39/75 (52%), Gaps = 3/75 (4%)
 Frame = +2

Query: 122 VMVSASEDATIKVWDYETGDFERTLKG-HTDSVQDISFDHSGKL-LASCSADMTIKLWDF 179
             ++ + +ATI+ WD  +      ++G H   V+D+ F+ + +  LASC  D  +K WD 
Sbjct: 623 AQIATANEATIRGWDLRSKQQTYQMEGAHGQLVRDLDFNPNRQYYLASCGDDCRVKFWDT 802

Query: 180 QGF-ECIRTMHGHDH 193
           +   E ++ +  H H
Sbjct: 803 RNCSEPLKVLSDHSH 847
>27681
          Length = 465

 Score = 29.6 bits (65), Expect(2) = 0.002,   Method: Compositional matrix adjust.
 Identities = 11/27 (40%), Positives = 18/27 (66%)
 Frame = +3

Query: 204 GDHIVSASRDKTIKMWEVQTGYCVKTF 230
           G++I+SA  DKT  +W+  +G C + F
Sbjct: 321 GNYILSAGVDKTTIIWDASSGSCTQQF 401

 Score = 29.3 bits (64), Expect(2) = 0.002,   Method: Compositional matrix adjust.
 Identities = 22/80 (27%), Positives = 37/80 (46%), Gaps = 14/80 (17%)
 Frame = +2

Query: 116 FHPVFSVMVSASEDATIKVWDY--ETGDFERTL-------KGHTD-----SVQDISFDHS 161
           ++P   ++ S S D+T ++W+   ET +    L       KG T+      V  + ++  
Sbjct: 17  WNPTNDLLASGSGDSTARIWNMTSETPNNANQLVLRHCIQKGGTEVPSNKDVTSLDWNSE 196

Query: 162 GKLLASCSADMTIKLWDFQG 181
           G LLA+ S D   +LW   G
Sbjct: 197 GTLLATGSYDGYARLWRTDG 256

 Score = 30.0 bits (66), Expect = 1.8,   Method: Compositional matrix adjust.
 Identities = 13/28 (46%), Positives = 17/28 (60%)
 Frame = +3

Query: 303 KSGKPGPFLLSGSRDKTIKMWDVSTGMC 330
           K  K G ++LS   DKT  +WD S+G C
Sbjct: 306 KWNKRGNYILSAGVDKTTIIWDASSGSC 389
>16199
          Length = 694

 Score = 32.3 bits (72), Expect(2) = 0.004,   Method: Compositional matrix adjust.
 Identities = 16/62 (25%), Positives = 34/62 (54%), Gaps = 1/62 (1%)
 Frame = +1

Query: 350 GKFILSCADDKTLRVWDYKNKRCMKTLNAHEHF-VTSLDFHKTAPYVVTGSVDQTVKVWE 408
           G ++ + A+D  +++WD +  +  KTL   + + V +L F ++  Y+     D  V+V+ 
Sbjct: 232 GYYLATSAEDSVVKLWDLRKLKNFKTLQLGDKYEVKALCFDQSGTYLAVAGSD--VRVYL 405

Query: 409 CR 410
           C+
Sbjct: 406 CK 411

 Score = 25.4 bits (54), Expect(2) = 0.004,   Method: Compositional matrix adjust.
 Identities = 11/39 (28%), Positives = 17/39 (43%)
 Frame = +2

Query: 308 GPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLF 346
           G    +G+ D  IK+WD+     +    GH   V  + F
Sbjct: 107 GLIFATGTEDSVIKIWDLKERANVANFQGHQGPVTSISF 223

 Score = 34.3 bits (77), Expect = 0.097,   Method: Compositional matrix adjust.
 Identities = 13/46 (28%), Positives = 23/46 (50%)
 Frame = +2

Query: 346 FHSGGKFILSCADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFHKT 391
           FH  G    +  +D  +++WD K +  +     H+  VTS+ F +T
Sbjct: 95  FHPDGLIFATGTEDSVIKIWDLKERANVANFQGHQGPVTSISFSET 232

 Score = 33.5 bits (75), Expect = 0.16,   Method: Compositional matrix adjust.
 Identities = 15/43 (34%), Positives = 22/43 (51%)
 Frame = +2

Query: 116 FHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISF 158
           FHP   +  + +ED+ IK+WD +        +GH   V  ISF
Sbjct: 95  FHPDGLIFATGTEDSVIKIWDLKERANVANFQGHQGPVTSISF 223

 Score = 28.5 bits (62), Expect = 5.2,   Method: Compositional matrix adjust.
 Identities = 16/59 (27%), Positives = 27/59 (45%), Gaps = 8/59 (13%)
 Frame = +2

Query: 202 PNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVR--------PNQDGTLIASC 252
           P+G    + + D  IK+W+++    V  F GH+  V  +         P Q  TL ++C
Sbjct: 101 PDGLIFATGTEDSVIKIWDLKERANVANFQGHQGPVTSISFSETDTTWPRQQKTLWSNC 277

 Score = 28.5 bits (62), Expect = 5.8,   Method: Compositional matrix adjust.
 Identities = 12/43 (27%), Positives = 21/43 (48%)
 Frame = +2

Query: 158 FDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAI 200
           F   G + A+ + D  IK+WD +    +    GH   V+S++ 
Sbjct: 95  FHPDGLIFATGTEDSVIKIWDLKERANVANFQGHQGPVTSISF 223
>15972
          Length = 1069

 Score = 38.9 bits (89), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 18/48 (37%), Positives = 24/48 (50%)
 Frame = +3

Query: 333 TLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTLNAHE 380
           T  GH   VR +  H  GK  L+ + D+TLR+W+  N R     N  E
Sbjct: 222 TFSGHKGPVRHLAVHPSGKLTLTVSQDRTLRLWNNMNGRIAFISNMKE 365

 Score = 36.6 bits (83), Expect = 0.020,   Method: Compositional matrix adjust.
 Identities = 20/64 (31%), Positives = 34/64 (53%), Gaps = 2/64 (3%)
 Frame = +3

Query: 93  EWIPRPPEKYALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETG--DFERTLKGHT 150
           E  P  PE+   SGH+ PV  +  HP   + ++ S+D T+++W+   G   F   +K   
Sbjct: 195 ECPPG*PER-TFSGHKGPVRHLAVHPSGKLTLTVSQDRTLRLWNNMNGRIAFISNMKEAA 371

Query: 151 DSVQ 154
           +SV+
Sbjct: 372 ESVR 383

 Score = 36.2 bits (82), Expect = 0.026,   Method: Compositional matrix adjust.
 Identities = 23/80 (28%), Positives = 36/80 (45%), Gaps = 10/80 (12%)
 Frame = +3

Query: 221 VQTGYCV----------KTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKA 270
           V+ G CV          +TF+GH+  VR +  +  G L  + S D+T+R+W        A
Sbjct: 168 VRMGPCVCGECPPG*PERTFSGHKGPVRHLAVHPSGKLTLTVSQDRTLRLWNNMNGRI-A 344

Query: 271 ELREHEHVVECISWAPESSY 290
            +   +   E + WAP   Y
Sbjct: 345 FISNMKEAAESVRWAPGGLY 404

 Score = 35.0 bits (79), Expect = 0.052,   Method: Compositional matrix adjust.
 Identities = 15/36 (41%), Positives = 22/36 (61%)
 Frame = +3

Query: 143 ERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLWD 178
           ERT  GH   V+ ++   SGKL  + S D T++LW+
Sbjct: 216 ERTFSGHKGPVRHLAVHPSGKLTLTVSQDRTLRLWN 323

 Score = 33.5 bits (75), Expect = 0.14,   Method: Compositional matrix adjust.
 Identities = 13/39 (33%), Positives = 23/39 (58%)
 Frame = +3

Query: 186 RTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTG 224
           RT  GH   V  +A+ P+G   ++ S+D+T+++W    G
Sbjct: 219 RTFSGHKGPVRHLAVHPSGKLTLTVSQDRTLRLWNNMNG 335
>31054
          Length = 392

 Score = 38.5 bits (88), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 25/105 (23%), Positives = 49/105 (46%), Gaps = 8/105 (7%)
 Frame = -2

Query: 311 LLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNK 370
              GS D  +K W    G  +  L GH+  +  +  +S G  ++S AD+ T+ +WD++  
Sbjct: 367 FAXGSPDX-VKQWKFPDGNFIQNLSGHNAIINTLAVNSDG-VLVSGADNGTMHLWDWRTG 194

Query: 371 RCMKTLNA--------HEHFVTSLDFHKTAPYVVTGSVDQTVKVW 407
              + ++A         E    +  F ++   ++T   D+T+KV+
Sbjct: 193 YNFQRIHAAVQPGSLDSESGFFACTFDQSESRLITAEADKTIKVY 59

 Score = 37.0 bits (84), Expect = 0.015,   Method: Compositional matrix adjust.
 Identities = 30/123 (24%), Positives = 59/123 (47%), Gaps = 9/123 (7%)
 Frame = -2

Query: 174 IKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGH 233
           +K W F     I+ + GH+  ++++A+  +G  +VS + + T+ +W+ +TGY  +     
Sbjct: 343 VKQWKFPDGNFIQNLSGHNAIINTLAVNSDG-VLVSGADNGTMHLWDWRTGYNFQ----- 182

Query: 234 REWVRMVRPNQDGTL-----IASCSNDQTVRVWVVATKECKAEL-REHEHVVE---CISW 284
               R+    Q G+L       +C+ DQ+    + A  +   ++ RE +   E    +SW
Sbjct: 181 ----RIHAAVQPGSLDSESGFFACTFDQSESRLITAEADKTIKVYREDDTATEETHPVSW 14

Query: 285 APE 287
            PE
Sbjct: 13  KPE 5

 Score = 33.9 bits (76), Expect = 0.11,   Method: Compositional matrix adjust.
 Identities = 23/110 (20%), Positives = 49/110 (44%), Gaps = 8/110 (7%)
 Frame = -2

Query: 118 PVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLW 177
           P  +V  +      +K W +  G+F + L GH   +  ++ +  G +L S + + T+ LW
Sbjct: 385 PSKAVHFAXGSPDXVKQWKFPDGNFIQNLSGHNAIINTLAVNSDG-VLVSGADNGTMHLW 209

Query: 178 DFQGFECIRTMHG--------HDHNVSSVAIMPNGDHIVSASRDKTIKMW 219
           D++     + +H          +    +     +   +++A  DKTIK++
Sbjct: 208 DWRTGYNFQRIHAAVQPGSLDSESGFFACTFDQSESRLITAEADKTIKVY 59

 Score = 32.3 bits (72), Expect = 0.37,   Method: Compositional matrix adjust.
 Identities = 15/56 (26%), Positives = 26/56 (46%)
 Frame = -2

Query: 206 HIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVW 261
           H    S D  +K W+   G  ++  +GH   +  +  N DG L++   N  T+ +W
Sbjct: 370 HFAXGSPDX-VKQWKFPDGNFIQNLSGHNAIINTLAVNSDGVLVSGADNG-TMHLW 209
>34005
          Length = 456

 Score = 38.5 bits (88), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 23/83 (27%), Positives = 39/83 (46%), Gaps = 6/83 (7%)
 Frame = +1

Query: 310 FLLSGSRDKTIKMWDVSTGM---CLMTLVGHDNWVRGVLFHSGGKFILSCA---DDKTLR 363
           FL SGS D ++ +WD + GM    L TL  H   V+ V +      +L+     +D+ +R
Sbjct: 154 FLASGSNDNSVNIWDSTLGMDVPPLHTLTSHQAAVKAVAWCPWQTRMLATGGGTNDRHIR 333

Query: 364 VWDYKNKRCMKTLNAHEHFVTSL 386
            W+     C+K ++      + L
Sbjct: 334 FWNTNTGACVKAVDTQSQVCSVL 402

 Score = 36.6 bits (83), Expect = 0.019,   Method: Compositional matrix adjust.
 Identities = 24/82 (29%), Positives = 39/82 (47%), Gaps = 6/82 (7%)
 Frame = +1

Query: 153 VQDISFDHSGKLLASCSADMTIKLWDFQ-GFEC--IRTMHGHDHNVSSVAIMPNGDHIVS 209
           V  +S+      LAS S D ++ +WD   G +   + T+  H   V +VA  P    +++
Sbjct: 121 VCGLSWSPDATFLASGSNDNSVNIWDSTLGMDVPPLHTLTSHQAAVKAVAWCPWQTRMLA 300

Query: 210 ---ASRDKTIKMWEVQTGYCVK 228
               + D+ I+ W   TG CVK
Sbjct: 301 TGGGTNDRHIRFWNTNTGACVK 366

 Score = 35.0 bits (79), Expect = 0.056,   Method: Compositional matrix adjust.
 Identities = 24/90 (26%), Positives = 40/90 (44%), Gaps = 3/90 (3%)
 Frame = +1

Query: 245 DGTLIASCSNDQTVRVW---VVATKECKAELREHEHVVECISWAPESSYSSISEATGSET 301
           D T +AS SND +V +W   +         L  H+  V+ ++W P   + +   ATG   
Sbjct: 145 DATFLASGSNDNSVNIWDSTLGMDVPPLHTLTSHQAAVKAVAWCP---WQTRMLATG--- 306

Query: 302 KKSGKPGPFLLSGSRDKTIKMWDVSTGMCL 331
                       G+ D+ I+ W+ +TG C+
Sbjct: 307 -----------GGTNDRHIRFWNTNTGACV 363
>11915
          Length = 737

 Score = 38.5 bits (88), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 21/59 (35%), Positives = 30/59 (50%), Gaps = 1/59 (1%)
 Frame = +1

Query: 122 VMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKL-LASCSADMTIKLWDF 179
           V+ +      IK+W+ ETG     +  H  +V D+ F     L L S S D T+KLW+F
Sbjct: 448 VLATGHVSGRIKLWNCETGKLLIEMMDHKATVHDLHFAADNSLCLMSASHDGTVKLWEF 624

 Score = 28.5 bits (62), Expect = 5.2,   Method: Compositional matrix adjust.
 Identities = 29/151 (19%), Positives = 59/151 (39%), Gaps = 1/151 (0%)
 Frame = +1

Query: 186 RTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQD 245
           +T+  HD N  ++ +     H++          + + T  C K     + W R  + +  
Sbjct: 280 KTLQKHDGN-DNMGLAGRQYHMIDCGEIVHAMAFGISTNNCYK-----QRWKRQQQNDSS 441

Query: 246 GTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSSISEATGSETKKSG 305
             ++A+      +++W   T +   E+ +H+  V  + +A ++S                
Sbjct: 442 TLVLATGHVSGRIKLWNCETGKLLIEMMDHKATVHDLHFAADNSLC-------------- 579

Query: 306 KPGPFLLSGSRDKTIKMWDV-STGMCLMTLV 335
                L+S S D T+K+W+    G C M L 
Sbjct: 580 -----LMSASHDGTVKLWEFDDQGDCNMYLT 657
>36111
          Length = 687

 Score = 38.1 bits (87), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 24/84 (28%), Positives = 37/84 (44%), Gaps = 12/84 (14%)
 Frame = +2

Query: 101 KYALSGHR---------SPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTL---KG 148
           KYA   HR          PV  V FH V++   +   D  + +WD   G  ++ L     
Sbjct: 182 KYAFKCHRIKEDSLEKIYPVNAVAFHNVYNTFATGGSDGYVNIWD---GFHKKRLCXFHR 352

Query: 149 HTDSVQDISFDHSGKLLASCSADM 172
           +  S+  ++F H G +LA  S+ M
Sbjct: 353 YPTSIASLAFSHDGNVLAIASSYM 424
>31384
          Length = 474

 Score = 37.7 bits (86), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 22/70 (31%), Positives = 35/70 (50%), Gaps = 2/70 (2%)
 Frame = -1

Query: 307 PGPFLLSGSRDKTIKMWDVS-TGMCLM-TLVGHDNWVRGVLFHSGGKFILSCADDKTLRV 364
           P  FL+SGS D  +  W+V  +G  +      H   V  V +   G  + + + DKT +V
Sbjct: 234 PSTFLISGSWDNKVSCWEVQQSGQTIPKAQQTHTGPVLDVDWSDDGTKVFTASCDKTAKV 55

Query: 365 WDYKNKRCMK 374
           WD  + +CM+
Sbjct: 54  WDLNSNQCMQ 25

 Score = 35.0 bits (79), Expect = 0.048,   Method: Compositional matrix adjust.
 Identities = 34/128 (26%), Positives = 57/128 (44%), Gaps = 5/128 (3%)
 Frame = -1

Query: 157 SFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNG---DHIVSASRD 213
           SF  S    ++  A  T  + DF+           D +VS +   P       ++S S D
Sbjct: 363 SFGQSNVFGSTAPAANTNPMKDFE------VTSPPDDSVSCLKFSPGALPSTFLISGSWD 202

Query: 214 KTIKMWEVQ-TGYCV-KTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAE 271
             +  WEVQ +G  + K    H   V  V  + DGT + + S D+T +VW + + +C  +
Sbjct: 201 NKVSCWEVQQSGQTIPKAQQTHTGPVLDVDWSDDGTKVFTASCDKTAKVWDLNSNQC-MQ 25

Query: 272 LREHEHVV 279
           + +H+  V
Sbjct: 24  IAQHDAPV 1

 Score = 32.0 bits (71), Expect = 0.42,   Method: Compositional matrix adjust.
 Identities = 27/93 (29%), Positives = 40/93 (43%), Gaps = 5/93 (5%)
 Frame = -1

Query: 141 DFERTLKGHTDSVQDISFDHSG---KLLASCSADMTIKLWDFQ--GFECIRTMHGHDHNV 195
           DFE T     DSV  + F         L S S D  +  W+ Q  G    +    H   V
Sbjct: 300 DFEVT-SPPDDSVSCLKFSPGALPSTFLISGSWDNKVSCWEVQQSGQTIPKAQQTHTGPV 124

Query: 196 SSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVK 228
             V    +G  + +AS DKT K+W++ +  C++
Sbjct: 123 LDVDWSDDGTKVFTASCDKTAKVWDLNSNQCMQ 25
>10264
          Length = 416

 Score = 37.7 bits (86), Expect = 0.009,   Method: Compositional matrix adjust.
 Identities = 23/84 (27%), Positives = 41/84 (48%), Gaps = 2/84 (2%)
 Frame = -1

Query: 185 IRTMHGHDHNVSSVAIMPNGD-HIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVR-P 242
           +R + GH   V+ ++  P+ D  +VS   D    +W+VQ G  +  F GH   +   +  
Sbjct: 266 LRELSGHSQRVTDMSWSPHHDARLVSVGYDAEAFVWDVQKGTALAQFKGHMGRLLTCQFS 87

Query: 243 NQDGTLIASCSNDQTVRVWVVATK 266
             D  L+ +  +D +V VW V+ +
Sbjct: 86  GLDPDLVMTGGSDASVHVWRVSQQ 15

 Score = 30.8 bits (68), Expect = 0.98,   Method: Compositional matrix adjust.
 Identities = 24/78 (30%), Positives = 35/78 (44%), Gaps = 4/78 (5%)
 Frame = -1

Query: 104 LSGHRSPVTRVIFHPVFSV-MVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSG 162
           LSGH   VT + + P     +VS   DA   VWD + G      KGH   +    F  SG
Sbjct: 257 LSGHSQRVTDMSWSPHHDARLVSVGYDAEAFVWDVQKGTALAQFKGHMGRLLTCQF--SG 84

Query: 163 ---KLLASCSADMTIKLW 177
               L+ +  +D ++ +W
Sbjct: 83  LDPDLVMTGGSDASVHVW 30
>04524
          Length = 1340

 Score = 37.4 bits (85), Expect = 0.011,   Method: Compositional matrix adjust.
 Identities = 22/81 (27%), Positives = 41/81 (50%), Gaps = 1/81 (1%)
 Frame = -1

Query: 188  MHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFT-GHREWVRMVRPNQDG 246
            + GH   V  V +     H+V+  RD+ I++ +    Y + T+  GH ++V  +   ++ 
Sbjct: 1040 LLGHLSMVLDVCLTGREGHVVTCDRDEKIRVSQFPNAYNIHTYCLGHTQFVNCLVYVEEF 861

Query: 247  TLIASCSNDQTVRVWVVATKE 267
             ++ S S D TVR W +  K+
Sbjct: 860  RVLISGSGDCTVRAWNMEGKQ 798

 Score = 31.2 bits (69), Expect = 0.79,   Method: Compositional matrix adjust.
 Identities = 16/54 (29%), Positives = 27/54 (50%), Gaps = 4/54 (7%)
 Frame = -1

Query: 89  RDPKEWIPRPPEKYALS----GHRSPVTRVIFHPVFSVMVSASEDATIKVWDYE 138
           RD K  + + P  Y +     GH   V  +++   F V++S S D T++ W+ E
Sbjct: 968 RDEKIRVSQFPNAYNIHTYCLGHTQFVNCLVYVEEFRVLISGSGDCTVRAWNME 807
>01598
          Length = 1545

 Score = 37.0 bits (84), Expect = 0.014,   Method: Compositional matrix adjust.
 Identities = 23/84 (27%), Positives = 41/84 (48%), Gaps = 2/84 (2%)
 Frame = +1

Query: 185  IRTMHGHDHNVSSVAIMPNGD-HIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVR-P 242
            +R + GH   V+ ++  P+ D  +VS   D    +W+VQ G  +  F GH   +   +  
Sbjct: 1279 LRELSGHSQRVTDMSWSPHHDARLVSVGYDAEAFVWDVQKGTALAQFKGHMGRLLTCQFS 1458

Query: 243  NQDGTLIASCSNDQTVRVWVVATK 266
              D  L+ +  +D +V VW V+ +
Sbjct: 1459 GLDPDLVMTGGSDASVHVWRVSQQ 1530

 Score = 30.8 bits (68), Expect = 0.92,   Method: Compositional matrix adjust.
 Identities = 22/76 (28%), Positives = 33/76 (43%), Gaps = 2/76 (2%)
 Frame = +1

Query: 104  LSGHRSPVTRVIFHPVFSV-MVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDH-S 161
            LSGH   VT + + P     +VS   DA   VWD + G      KGH   +    F    
Sbjct: 1288 LSGHSQRVTDMSWSPHHDARLVSVGYDAEAFVWDVQKGTALAQFKGHMGRLLTCQFSGLD 1467

Query: 162  GKLLASCSADMTIKLW 177
              L+ +  +D ++ +W
Sbjct: 1468 PDLVMTGGSDASVHVW 1515

 Score = 28.1 bits (61), Expect = 6.1,   Method: Compositional matrix adjust.
 Identities = 15/54 (27%), Positives = 27/54 (50%), Gaps = 4/54 (7%)
 Frame = +1

Query: 279 VECISWAPESSYSSISEA----TGSETKKSGKPGPFLLSGSRDKTIKMWDVSTG 328
           V  +SW P    + + E+     G    +    G  + +GS+D+TI++W +S G
Sbjct: 1   VMSVSWCPVQGETFLKESQDATNGLTDPERDTGGCLIATGSKDRTIRVWTLSQG 162
>16105
          Length = 960

 Score = 37.0 bits (84), Expect = 0.015,   Method: Compositional matrix adjust.
 Identities = 35/145 (24%), Positives = 62/145 (42%), Gaps = 9/145 (6%)
 Frame = -2

Query: 98  PPEKYALSGHRSPVTRVIFHP-VFSVMVSASEDATIKVWDYETGDFERTLK-------GH 149
           P +   ++GH+  V  + + P   +V+ SAS+D T+KVW          L        GH
Sbjct: 605 PVDNPLVAGHKGAVLDIQWCPHNDNVIASASDDCTVKVWQIPDSGLVTNLTDPVVDLVGH 426

Query: 150 TDSVQDISFDHSGK-LLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIV 208
                 I +  S + +L S  AD  I  W+    E +  +   D  +  ++   NG  +V
Sbjct: 425 QKRCCLIVWHPSAQNVLVSAGADNKILFWNVGTGEPMLEVDVPDM-IYCMSFNFNGSRLV 249

Query: 209 SASRDKTIKMWEVQTGYCVKTFTGH 233
              +DK +++ +  +G  +K    H
Sbjct: 248 CTCKDKKLRIIDSHSGAVLKEGKCH 174

 Score = 32.7 bits (73), Expect = 0.29,   Method: Compositional matrix adjust.
 Identities = 27/105 (25%), Positives = 49/105 (46%), Gaps = 10/105 (9%)
 Frame = -2

Query: 190 GHDHNVSSVAIMPNGDHIV-SASRDKTIKMWEVQTGYCVKTFT-------GHREWVRMV- 240
           GH   V  +   P+ D+++ SAS D T+K+W++     V   T       GH++   ++ 
Sbjct: 581 GHKGAVLDIQWCPHNDNVIASASDDCTVKVWQIPDSGLVTNLTDPVVDLVGHQKRCCLIV 402

Query: 241 -RPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISW 284
             P+    L+ S   D  +  W V T E   E+ +   ++ C+S+
Sbjct: 401 WHPSAQNVLV-SAGADNKILFWNVGTGEPMLEV-DVPDMIYCMSF 273
>14500
          Length = 1238

 Score = 36.6 bits (83), Expect = 0.018,   Method: Compositional matrix adjust.
 Identities = 15/54 (27%), Positives = 31/54 (57%)
 Frame = +3

Query: 170 ADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQT 223
           A   + +W +     +  + GH   V  +A+ P+G+ +VSA+ D+T+++W+  T
Sbjct: 399 AQNQLIIWKYPAMSRVAELTGHTARVLHMAMSPDGETVVSAAADETLRLWKCFT 560

 Score = 33.1 bits (74), Expect = 0.22,   Method: Compositional matrix adjust.
 Identities = 26/106 (24%), Positives = 48/106 (45%), Gaps = 5/106 (4%)
 Frame = +3

Query: 309 PFLLS---GSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCAD--DKTLR 363
           P LL+   G+ D+ I  W+ +TG  L + V   + V  +L+    + ++S        L 
Sbjct: 240 PSLLASGGGTADRHIHFWNCNTGTNLSS-VDTKSQVCALLWSKEHRELISSHGFAQNQLI 416

Query: 364 VWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWEC 409
           +W Y     +  L  H   V  +        VV+ + D+T+++W+C
Sbjct: 417 IWKYPAMSRVAELTGHTARVLHMAMSPDGETVVSAAADETLRLWKC 554

 Score = 28.9 bits (63), Expect = 3.8,   Method: Compositional matrix adjust.
 Identities = 14/35 (40%), Positives = 21/35 (60%)
 Frame = +2

Query: 227 VKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVW 261
           V T +GH + V  +R + DG  +AS +ND  + VW
Sbjct: 38  VGTLSGHSQEVCGLRWSPDGKYLASGANDNLLCVW 142

 Score = 28.9 bits (63), Expect = 4.5,   Method: Compositional matrix adjust.
 Identities = 14/41 (34%), Positives = 23/41 (56%)
 Frame = +3

Query: 104 LSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFER 144
           L+GH + V  +   P    +VSA+ D T+++W   T D E+
Sbjct: 453 LTGHTARVLHMAMSPDGETVVSAAADETLRLWKCFTVDKEK 575

 Score = 28.1 bits (61), Expect = 6.4,   Method: Compositional matrix adjust.
 Identities = 16/61 (26%), Positives = 30/61 (49%), Gaps = 5/61 (8%)
 Frame = +2

Query: 185 IRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQ-TG----YCVKTFTGHREWVRM 239
           + T+ GH   V  +   P+G ++ S + D  + +W  Q TG      + TF+ H+  V+ 
Sbjct: 38  VGTLSGHSQEVCGLRWSPDGKYLASGANDNLLCVWPAQVTGGNSTQPLHTFSQHQAAVKA 217

Query: 240 V 240
           +
Sbjct: 218 L 220

 Score = 27.7 bits (60), Expect = 8.2,   Method: Compositional matrix adjust.
 Identities = 18/59 (30%), Positives = 30/59 (50%), Gaps = 5/59 (8%)
 Frame = +2

Query: 333 TLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYK-----NKRCMKTLNAHEHFVTSL 386
           TL GH   V G+ +   GK++ S A+D  L VW  +     + + + T + H+  V +L
Sbjct: 44  TLSGHSQEVCGLRWSPDGKYLASGANDNLLCVWPAQVTGGNSTQPLHTFSQHQAAVKAL 220
>25400
          Length = 462

 Score = 35.4 bits (80), Expect = 0.043,   Method: Compositional matrix adjust.
 Identities = 15/33 (45%), Positives = 21/33 (63%)
 Frame = +3

Query: 105 SGHRSPVTRVIFHPVFSVMVSASEDATIKVWDY 137
            GHRS V  V +HP  + ++S+S D T+  WDY
Sbjct: 81  GGHRSCVRDVSWHPYTNTLISSSWDGTVGKWDY 179

 Score = 32.0 bits (71), Expect = 0.53,   Method: Compositional matrix adjust.
 Identities = 20/58 (34%), Positives = 28/58 (48%), Gaps = 1/58 (1%)
 Frame = +3

Query: 123 MVSASEDATIKVWDYETGDFERTLKG-HTDSVQDISFDHSGKLLASCSADMTIKLWDF 179
           + S     TI ++D  TG   R L G H   V+D+S+      L S S D T+  WD+
Sbjct: 6   VYSGCATGTILIYDLLTGRVVRKLDGGHRSCVRDVSWHPYTNTLISSSWDGTVGKWDY 179
>12841
          Length = 1364

 Score = 34.7 bits (78), Expect = 0.064,   Method: Compositional matrix adjust.
 Identities = 21/81 (25%), Positives = 34/81 (41%), Gaps = 1/81 (1%)
 Frame = +1

Query: 142  FERTLKGHTDSVQDISFD-HSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAI 200
            +  T  GHT  V  I +      +  SCSAD +I+LW       I T H     V  V  
Sbjct: 1024 YLETYSGHTAPVYHIRWSPFVSDIFLSCSADWSIRLWHQDRTTPILTFHSSTKTVHDVCW 1203

Query: 201  MPNGDHIVSASRDKTIKMWEV 221
             P    + +   +  +++W++
Sbjct: 1204 SPRSSTVFACVHEGAVEVWDL 1266
>20271
          Length = 567

 Score = 34.7 bits (78), Expect = 0.067,   Method: Compositional matrix adjust.
 Identities = 23/85 (27%), Positives = 42/85 (49%), Gaps = 10/85 (11%)
 Frame = -1

Query: 103 ALSGHRSPVT---------RVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSV 153
           A  GH+ P+T         ++ F P F   ++AS D T+K+W+ +   +  + + ++D V
Sbjct: 300 AYEGHQGPITAIDTHHAAGQIDFSPFF---LTASFDWTVKLWNIKEQKYVCSFEDNSDYV 130

Query: 154 QDISFDHSGKLLASCSADMT-IKLW 177
            D+ +  +   L SC   M  + LW
Sbjct: 129 SDVQWSPTNPALFSCVDIMGRLDLW 55

 Score = 30.0 bits (66), Expect = 1.8,   Method: Compositional matrix adjust.
 Identities = 13/50 (26%), Positives = 25/50 (50%)
 Frame = -1

Query: 309 PFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCAD 358
           PF L+ S D T+K+W++     + +   + ++V  V +      + SC D
Sbjct: 228 PFFLTASFDWTVKLWNIKEQKYVCSFEDNSDYVSDVQWSPTNPALFSCVD 79
>35695
          Length = 1651

 Score = 34.3 bits (77), Expect = 0.085,   Method: Compositional matrix adjust.
 Identities = 18/49 (36%), Positives = 27/49 (55%), Gaps = 1/49 (2%)
 Frame = -1

Query: 360  KTLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTA-PYVVTGSVDQTVKVW 407
            K L VWD K    +KTL+AH   + +L         V++ S+D+T+ VW
Sbjct: 1645 KNLYVWDVKQGNMVKTLDAHFGRIIALTSVTVGCNMVISSSIDKTINVW 1499

 Score = 33.1 bits (74), Expect = 0.22,   Method: Compositional matrix adjust.
 Identities = 39/159 (24%), Positives = 63/159 (39%), Gaps = 4/159 (2%)
 Frame = -1

Query: 214  KTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDG-TLIASCSNDQTVRVWVV-ATKECKAE 271
            K + +W+V+ G  VKT   H   +  +     G  ++ S S D+T+ VW      E    
Sbjct: 1645 KNLYVWDVKQGNMVKTLDAHFGRIIALTSVTVGCNMVISSSIDKTINVWNFDKILEEVHP 1466

Query: 272  LREHEHVVECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCL 331
            L   E  +E +  A  SS                      ++ +R++T  +WD+ TG  +
Sbjct: 1465 LDRMERPIETVHMAASSS--------------------LCVATTRNQT-SVWDLETGRLV 1349

Query: 332  MTLVG--HDNWVRGVLFHSGGKFILSCADDKTLRVWDYK 368
              LVG    N V        G  +L+ A+  +L VW   
Sbjct: 1348 KVLVGSSRSNXVSQAFITREGTHVLT-AESPSLLVWQMN 1235
>30108
          Length = 1032

 Score = 33.1 bits (74), Expect = 0.21,   Method: Compositional matrix adjust.
 Identities = 24/130 (18%), Positives = 53/130 (40%), Gaps = 14/130 (10%)
 Frame = +1

Query: 111 VTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGK------- 163
           V  + + P+ + +++ +  + + +W  E        +  + SVQ +   HSG        
Sbjct: 235 VAHLAWQPLSASVLAVACQSAVLIWHIEPTSLAA--RPSSSSVQVL--QHSGHCPITHLA 402

Query: 164 -------LLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTI 216
                  LL++   D  +  W   G  C    +     VS +A  P+G  +++A+     
Sbjct: 403 WLPSANILLSASPVDTAVMAWSVGGEACTALRYLGGGGVSLLACSPDGSKVMAATPATLF 582

Query: 217 KMWEVQTGYC 226
           ++W+  + +C
Sbjct: 583 RVWDTTSWHC 612

 Score = 28.1 bits (61), Expect = 7.2,   Method: Compositional matrix adjust.
 Identities = 32/174 (18%), Positives = 67/174 (38%), Gaps = 11/174 (6%)
 Frame = +1

Query: 107 HRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTD-SVQDISFDHSGKLL 165
           H SPV    +HP  +    A +D ++ V  Y        LK     SV  +++      +
Sbjct: 97  HESPVRAFAWHPHTTKFALALQDNSVHV-HYSASTLVPVLKHKLQKSVAHLAWQPLSASV 273

Query: 166 ASCSADMTIKLWDFQ--------GFECIRTMHGHDH-NVSSVAIMPNGDHIVSASR-DKT 215
            + +    + +W  +            ++ +    H  ++ +A +P+ + ++SAS  D  
Sbjct: 274 LAVACQSAVLIWHIEPTSLAARPSSSSVQVLQHSGHCPITHLAWLPSANILLSASPVDTA 453

Query: 216 IKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECK 269
           +  W V    C          V ++  + DG+ + + +     RVW   +  C+
Sbjct: 454 VMAWSVGGEACTALRYLGGGGVSLLACSPDGSKVMAATPATLFRVWDTTSWHCE 615
>17298
          Length = 476

 Score = 33.1 bits (74), Expect = 0.22,   Method: Compositional matrix adjust.
 Identities = 30/108 (27%), Positives = 49/108 (45%), Gaps = 20/108 (18%)
 Frame = -1

Query: 318 KTIKMW-----------------DVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDK 360
           KT+KMW                 +V++G  L     H   V  V F+     ILS + D 
Sbjct: 323 KTVKMWQRRQVCWHICDGVVVGNNVASGQALRKYRDHAGTVNCVKFNEESTVILSGSLDN 144

Query: 361 TLRVWDYKNKR--CMKTLNAHEHFVTSLDFHKTAPY-VVTGSVDQTVK 405
           T+R WD +++    ++ L+     VTS+   + + Y ++TGS D  V+
Sbjct: 143 TVRAWDTRSRSHTPIQVLDEATDSVTSI---QVSDYEILTGSADGRVR 9

 Score = 27.7 bits (60), Expect = 8.3,   Method: Compositional matrix adjust.
 Identities = 16/62 (25%), Positives = 26/62 (41%)
 Frame = -1

Query: 263 VATKECKAELREHEHVVECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKM 322
           VA+ +   + R+H   V C+ +  ES+                     +LSGS D T++ 
Sbjct: 251 VASGQALRKYRDHAGTVNCVKFNEEST--------------------VILSGSLDNTVRA 132

Query: 323 WD 324
           WD
Sbjct: 131 WD 126
>38177
          Length = 430

 Score = 32.7 bits (73), Expect = 0.25,   Method: Compositional matrix adjust.
 Identities = 23/85 (27%), Positives = 38/85 (44%)
 Frame = +3

Query: 162 GKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEV 221
           G+ L + ++     LW+   F     +  HD +V ++    +   +V+A     IK W+ 
Sbjct: 24  GRRLVTGASSGEFTLWNGLTFNFETILQAHDVSVRAMRWSNHDQWMVTADHSGYIKYWQS 203

Query: 222 QTGYCVKTFTGHREWVRMVRPNQDG 246
                VK F GH+E +R VR    G
Sbjct: 204 NMNN-VKMFQGHKEPIRGVRLAPPG 275
>30295
          Length = 593

 Score = 32.7 bits (73), Expect = 0.25,   Method: Compositional matrix adjust.
 Identities = 25/102 (24%), Positives = 46/102 (45%), Gaps = 4/102 (3%)
 Frame = +2

Query: 123 MVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQGF 182
           +VSAS+D  + VWD  T +    +   +  V   ++  SG  +A    D    ++  +  
Sbjct: 290 LVSASQDGKLIVWDGYTTNKVHAIPLRSSWVMTCAYAPSGGYVACGGLDNICSIYSLKTR 469

Query: 183 E----CIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWE 220
           E      R + GH   +S    + + + IV++S D T  +W+
Sbjct: 470 EGNVRVSRELPGHTGYLSCCRFIDD-NQIVTSSGDMTCALWD 592

 Score = 31.2 bits (69), Expect = 0.89,   Method: Compositional matrix adjust.
 Identities = 25/123 (20%), Positives = 48/123 (39%), Gaps = 4/123 (3%)
 Frame = +2

Query: 143 ERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMP 202
            RTL+ H   +  + +    + L S S D  + +WD      +  +      V + A  P
Sbjct: 224 RRTLRXHLAKIYAMHWATDSRNLVSASQDGKLIVWDGYTTNKVHAIPLRSSWVMTCAYAP 403

Query: 203 NGDHIVSASRDKTIKMWEVQTG----YCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTV 258
           +G ++     D    ++ ++T        +   GH  ++   R   D  ++ S S D T 
Sbjct: 404 SGGYVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFIDDNQIVTS-SGDMTC 580

Query: 259 RVW 261
            +W
Sbjct: 581 ALW 589

 Score = 30.8 bits (68), Expect = 0.96,   Method: Compositional matrix adjust.
 Identities = 23/102 (22%), Positives = 42/102 (41%), Gaps = 4/102 (3%)
 Frame = +2

Query: 311 LLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYK-- 368
           L+S S+D  + +WD  T   +  +    +WV    +   G ++     D    ++  K  
Sbjct: 290 LVSASQDGKLIVWDGYTTNKVHAIPLRSSWVMTCAYAPSGGYVACGGLDNICSIYSLKTR 469

Query: 369 --NKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWE 408
             N R  + L  H  +++   F      +VT S D T  +W+
Sbjct: 470 EGNVRVSRELPGHTGYLSCCRFIDDNQ-IVTSSGDMTCALWD 592
>30297
          Length = 822

 Score = 32.3 bits (72), Expect = 0.34,   Method: Compositional matrix adjust.
 Identities = 22/89 (24%), Positives = 42/89 (47%), Gaps = 13/89 (14%)
 Frame = -1

Query: 106 GHRSP---VTRVIFHPVFSVMVSASEDATIKVWDY----------ETGDFERTLKGHTDS 152
           G +SP   V+ +  +   +++ SA     I VWD           ++ D  ++ +GH +S
Sbjct: 399 GSKSPGGMVSAMATNKANTLLYSADSLGFIYVWDISQYCLETPETDSPDVIQSWRGHVES 220

Query: 153 VQDISFDHSGKLLASCSADMTIKLWDFQG 181
           V  +      K+L + +AD T+++W   G
Sbjct: 219 VSCLDLVEQNKVLLTSAADCTVRMWTTDG 133

 Score = 29.3 bits (64), Expect = 2.7,   Method: Compositional matrix adjust.
 Identities = 20/94 (21%), Positives = 43/94 (45%), Gaps = 10/94 (10%)
 Frame = -1

Query: 153 VQDISFDHSGKLLASCSADMTIKLWDFQGF----------ECIRTMHGHDHNVSSVAIMP 202
           V  ++ + +  LL S  +   I +WD   +          + I++  GH  +VS + ++ 
Sbjct: 375 VSAMATNKANTLLYSADSLGFIYVWDISQYCLETPETDSPDVIQSWRGHVESVSCLDLVE 196

Query: 203 NGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREW 236
               +++++ D T++MW    G+ + TF     W
Sbjct: 195 QNKVLLTSAADCTVRMWTTD-GHYIGTFGQPELW 97
>30679
          Length = 1025

 Score = 32.3 bits (72), Expect = 0.36,   Method: Compositional matrix adjust.
 Identities = 15/58 (25%), Positives = 31/58 (53%)
 Frame = +1

Query: 121 SVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLWD 178
           ++++SA  D    VW+ E  +    +  HTD++  +S++  G + A+ S D  ++  D
Sbjct: 1   NILLSAGFDYKCVVWNVEQAEPVNIVDCHTDTIFSMSWNRXGSMFATTSKDKKLRTID 174
>31864
          Length = 545

 Score = 32.3 bits (72), Expect = 0.37,   Method: Compositional matrix adjust.
 Identities = 15/49 (30%), Positives = 25/49 (51%), Gaps = 1/49 (2%)
 Frame = +2

Query: 100 EKYA-LSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLK 147
           E++A L GH  P+  + FHP      S  ED  ++V  +++  FE   +
Sbjct: 314 EEFARLKGHFGPINSLAFHPDGKSYASGGEDGFVRVKSFDSTYFENIFE 460
>05393
          Length = 904

 Score = 32.0 bits (71), Expect = 0.42,   Method: Compositional matrix adjust.
 Identities = 19/51 (37%), Positives = 28/51 (54%), Gaps = 5/51 (9%)
 Frame = +1

Query: 102 YALSGHRSPVTRVIFHP-VFSVMVSASEDATIKVWDYE----TGDFERTLK 147
           +++  H S VT V     +  +M++ SED T+KVWD +    T  F R LK
Sbjct: 202 FSVGAHSSCVTGVCLSSQIPGLMITTSEDKTMKVWDIQDDKPTHVFSRNLK 354

 Score = 30.0 bits (66), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 26/105 (24%), Positives = 53/105 (50%), Gaps = 5/105 (4%)
 Frame = +1

Query: 123 MVSASEDATIKVWD---YETGDFERTLKGHTDSVQDISFDHSGKL-LASCSADMTIKLWD 178
           +++ S D T+KV D    ET     T++G    V+   ++H   L L +C+    +  +D
Sbjct: 10  LLTGSFDNTVKVVDCRSAETCHKSWTVEG---EVEKAVWNHHNPLQLLACTDKGMVYCFD 180

Query: 179 FQGFECIRTMHGHDHNVSSVAIMPN-GDHIVSASRDKTIKMWEVQ 222
            +  + + ++  H   V+ V +       +++ S DKT+K+W++Q
Sbjct: 181 IRHEKPVFSVGAHSSCVTGVCLSSQIPGLMITTSEDKTMKVWDIQ 315

 Score = 28.9 bits (63), Expect = 4.2,   Method: Compositional matrix adjust.
 Identities = 27/110 (24%), Positives = 49/110 (44%), Gaps = 8/110 (7%)
 Frame = +1

Query: 309 PFLLSGSRDK-TIKMWDVSTGMCLMTLVGHDNWVRGVLFHSG-GKFILSCADDKTLRVWD 366
           P  L    DK  +  +D+     + ++  H + V GV   S     +++ ++DKT++VWD
Sbjct: 130 PLQLLACTDKGMVYCFDIRHEKPVFSVGAHSSCVTGVCLSSQIPGLMITTSEDKTMKVWD 309

Query: 367 YKNKRCMKTLNAHEHFVTSLDFHKT-----APYV-VTGSVDQTVKVWECR 410
            ++    K  +     +   + H T     AP+V   G   +  KVW+ R
Sbjct: 310 IQDD---KPTHVFSRNLKMKELHCTGCCPEAPFVFAVGGGRREPKVWDIR 450
>07741
          Length = 2119

 Score = 32.0 bits (71), Expect = 0.45,   Method: Compositional matrix adjust.
 Identities = 16/44 (36%), Positives = 26/44 (59%), Gaps = 1/44 (2%)
 Frame = +1

Query: 139 TGDFERTLKGHTDSVQDISFDH-SGKLLASCSADMTIKLWDFQG 181
           T  F  TL  H  +V  ++++H   K+ A+CSAD  +K+W+  G
Sbjct: 208 TSHFIDTLDSHNMAVYKVAWNHYHPKIYATCSADWNVKIWENGG 339
>25880
          Length = 423

 Score = 31.6 bits (70), Expect = 0.58,   Method: Compositional matrix adjust.
 Identities = 25/90 (27%), Positives = 44/90 (48%), Gaps = 1/90 (1%)
 Frame = +2

Query: 173 TIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEV-QTGYCVKTFT 231
           T K+W+      I +   H H V SVA   + ++IV+ S +K ++++ + Q     + + 
Sbjct: 2   TGKVWNAVSGAEIHSFQ-HKHIVKSVAFDNSSENIVTGSNEKLVRVFNLEQPDAEPELYG 178

Query: 232 GHREWVRMVRPNQDGTLIASCSNDQTVRVW 261
           GH   ++         L AS S D T+R+W
Sbjct: 179 GHTGAIKRA-------LYASGSEDGTLRLW 247
>13486
          Length = 1509

 Score = 31.2 bits (69), Expect = 0.85,   Method: Compositional matrix adjust.
 Identities = 14/36 (38%), Positives = 20/36 (55%)
 Frame = -1

Query: 146 LKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQG 181
           L GH+  V D+ F+    LLASC A   + +W  +G
Sbjct: 912 LLGHSAPVLDVCFNCDESLLASCDAQGMVIIWKREG 805
>31118
          Length = 390

 Score = 31.2 bits (69), Expect = 0.91,   Method: Composition-based stats.
 Identities = 14/33 (42%), Positives = 19/33 (57%)
 Frame = -2

Query: 149 HTDSVQDISFDHSGKLLASCSADMTIKLWDFQG 181
           H+  ++ I F  S   + +CS D TIKL D QG
Sbjct: 383 HSAEIRCIRFSPSAYYMLTCSYDSTIKLTDLQG 285
>04088
          Length = 511

 Score = 30.8 bits (68), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 21/81 (25%), Positives = 36/81 (44%), Gaps = 2/81 (2%)
 Frame = +3

Query: 110 PVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDIS--FDHSGKLLAS 167
            VT V F       + +S+D T+++ D +TG+      GH  S   I    ++   L+ S
Sbjct: 36  AVTSVTFTRDGQCSLVSSQDNTVRLMDKDTGEMLNEFTGHKHSQYKIDSCLNNEDTLVVS 215

Query: 168 CSADMTIKLWDFQGFECIRTM 188
            S D  +  WD    + + T+
Sbjct: 216 GSEDGKVYFWDLVEAKLVDTL 278
>12140
          Length = 727

 Score = 30.4 bits (67), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 29/97 (29%), Positives = 44/97 (45%), Gaps = 9/97 (9%)
 Frame = +2

Query: 207 IVSASRDKTIKMW-EVQTGYCV-KTFTGHREWVRMVRPNQDGTL----IASCSNDQTVRV 260
            VS   D  +K+W E +TG+   +   GH +WVR V       L    IASCS D  V +
Sbjct: 269 FVSGGCDNLVKIWREDETGWVEDQKLEGHSDWVRDVAWAPSIGLPRNVIASCSQDCRVII 448

Query: 261 WV---VATKECKAELREHEHVVECISWAPESSYSSIS 294
           W     + +     L +   VV  +SW+   +  ++S
Sbjct: 449 WTNDGSSNQWTSRILNKFSDVVWHVSWSVTGNILAVS 559
>21960
          Length = 756

 Score = 29.6 bits (65), Expect = 2.4,   Method: Compositional matrix adjust.
 Identities = 18/64 (28%), Positives = 28/64 (43%), Gaps = 1/64 (1%)
 Frame = +1

Query: 115 IFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDH-SGKLLASCSADMT 173
            F P    ++S S+D  I  WD  T      +KG    V +    H +  +LA+   D  
Sbjct: 385 FFGPHSEHIISGSDDGNIFYWDKNTEAVTNFMKGDDAGVVNCLEQHPTMPVLATSGLDHN 564

Query: 174 IKLW 177
           +K+W
Sbjct: 565 VKIW 576
>22113
          Length = 614

 Score = 28.9 bits (63), Expect = 3.8,   Method: Compositional matrix adjust.
 Identities = 21/73 (28%), Positives = 32/73 (43%), Gaps = 1/73 (1%)
 Frame = +3

Query: 337 HDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTLNAHE-HFVTSLDFHKTAPYV 395
           H++ V  + F + GK+ +S   D  L  W  +         + E   V S D      Y+
Sbjct: 99  HESCVLSLRFATCGKWFVSTGKDNLLNAW--RTPYGASIFQSKETSSVLSCDISTDDKYI 272

Query: 396 VTGSVDQTVKVWE 408
           VTGS D+   V+E
Sbjct: 273 VTGSGDKKATVYE 311
>13509
          Length = 572

 Score = 28.9 bits (63), Expect = 3.9,   Method: Compositional matrix adjust.
 Identities = 17/84 (20%), Positives = 30/84 (35%), Gaps = 11/84 (13%)
 Frame = +2

Query: 98  PPEKYALSGHRS-----------PVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTL 146
           P + +    HRS            V  + FHPV   + +   D     WD +     +T 
Sbjct: 296 PKDNFTFKCHRSNGASNNVQDIYAVNDISFHPVHGTLSTVGSDGRFSFWDKDARTKLKTS 475

Query: 147 KGHTDSVQDISFDHSGKLLASCSA 170
           +     +   +F+  G + A  S+
Sbjct: 476 EQFDQPITTCNFNAQGNIFAYASS 547
>34511
          Length = 1037

 Score = 28.9 bits (63), Expect = 4.1,   Method: Compositional matrix adjust.
 Identities = 10/33 (30%), Positives = 19/33 (57%)
 Frame = +3

Query: 188 MHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWE 220
           + GHD+ VS + +  NG  + + S D  +++W 
Sbjct: 60  LAGHDNRVSCLGVTENGMSVATGSWDSFLRVWN 158
>33180
          Length = 460

 Score = 28.5 bits (62), Expect = 5.1,   Method: Compositional matrix adjust.
 Identities = 11/16 (68%), Positives = 14/16 (87%)
 Frame = -1

Query: 310 FLLSGSRDKTIKMWDV 325
            LLS S+D+TIK+WDV
Sbjct: 142 LLLSNSKDQTIKLWDV 95
>06576
          Length = 1547

 Score = 28.5 bits (62), Expect = 5.8,   Method: Compositional matrix adjust.
 Identities = 23/96 (23%), Positives = 43/96 (44%), Gaps = 3/96 (3%)
 Frame = -2

Query: 279  VECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMW--DVSTGMCLMTLVG 336
            V C++W+P +S SS+ +                 +   D +++++  D+ T      + G
Sbjct: 1231 VSCLAWSPSTSLSSLDKHLC------------FAAACDDHSVRVFTSDLKTTNKTHVVKG 1088

Query: 337  HDNWVRGVLFHSGGK-FILSCADDKTLRVWDYKNKR 371
            H ++V  V F    +  + S  DD T RVW  K+ +
Sbjct: 1087 HTDFVNSVTFSPTEEDQVXSTGDDLTCRVWTGKDGQ 980
>17807
          Length = 484

 Score = 28.1 bits (61), Expect = 6.2,   Method: Compositional matrix adjust.
 Identities = 24/111 (21%), Positives = 46/111 (41%), Gaps = 10/111 (9%)
 Frame = -2

Query: 310 FLLSGSRDKTIKMWDVSTGMCLM--TLVGHDNWVRGVLF-HSGGKFILSCADDKT----- 361
           + LSGS D  I++W++      M   L G  N +    F H+G   ++   D +      
Sbjct: 417 YFLSGSLDGKIRLWNIPDKKVTMWNELSGSSNLITTASFCHNGRLAVVGTYDGRCIFYTT 238

Query: 362 --LRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWECR 410
             L+ +   N R  +  NA    +T ++       ++  S D  V+++  +
Sbjct: 237 DQLKYYTMLNVRSTRGRNARGRKITGIEAMPGEEKILVTSNDSRVRLYSLK 85
>30727
          Length = 402

 Score = 28.1 bits (61), Expect = 6.6,   Method: Composition-based stats.
 Identities = 16/52 (30%), Positives = 23/52 (44%), Gaps = 1/52 (1%)
 Frame = +1

Query: 337 HDNWVRGVLFHSGGKF-ILSCADDKTLRVWDYKNKRCMKTLNAHEHFVTSLD 387
           H N    VLF +   + +LS   D  L  WD+   +C+   N  E   T+ D
Sbjct: 58  HTNICSTVLFRNNRPWEVLSGGMDSRLVHWDFSKPKCLNQFNMQELHSTTSD 213
>35607
          Length = 475

 Score = 27.7 bits (60), Expect = 8.0,   Method: Compositional matrix adjust.
 Identities = 37/168 (22%), Positives = 63/168 (37%), Gaps = 4/168 (2%)
 Frame = +2

Query: 245 DGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECIS--WAPESSYSSIS-EATGSET 301
           DGT + +   D TVR W +       +L++H+   +  S  + P   + ++  E++  E 
Sbjct: 11  DGTKLWTGGLDNTVRSWDLREGR---QLQQHDFSSQIFSLGYCPTGDWLAVGMESSNVEV 181

Query: 302 KKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKT 361
               KP  + L                        H++ V  + F   GK+ +S   D  
Sbjct: 182 LHHSKPDKYQLHL----------------------HESCVLSLKFAYCGKWFVSTGKDNL 295

Query: 362 LRVWDYKNKRCMKTLNAHEHF-VTSLDFHKTAPYVVTGSVDQTVKVWE 408
           L  W  +         + E   V S D      Y+VTGS D+   ++E
Sbjct: 296 LNAW--RTPYGASIFQSKESSSVLSCDIAADDKYIVTGSGDKKATLYE 433
>05188
          Length = 970

 Score = 27.7 bits (60), Expect = 8.8,   Method: Compositional matrix adjust.
 Identities = 14/33 (42%), Positives = 20/33 (60%)
 Frame = +1

Query: 276 EHVVECISWAPESSYSSISEATGSETKKSGKPG 308
           E VV C S A +SSY+    ++GS+ +  GK G
Sbjct: 640 ESVVSCSSDAKDSSYADCLSSSGSKPRSVGKNG 738
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|30520019|ref|NP_848768.1| saccharopine dehydrogenase
(putative) [Mus musculus]
         (429 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

26323                                                                 131   5e-31
19883                                                                  30   1.5  
>26323
          Length = 574

 Score =  131 bits (329), Expect = 5e-31,   Method: Compositional matrix adjust.
 Identities = 67/171 (39%), Positives = 97/171 (56%), Gaps = 4/171 (2%)
 Frame = -3

Query: 258 RTQRYLHENLEDSPVQYAAYVTVGGITSVIKXXXXXXXXXXXXXXSIGRQLLIKFPWLFS 317
           R+QRY  +  +  PVQ+  Y+   G  +                 S+ R LL+KFP  F+
Sbjct: 554 RSQRYAFDTNKQRPVQFIPYLCNSGRLATYLMGFFAIIFGIMVRFSLTRYLLLKFPSFFT 375

Query: 318 FGYFSKQGPTQKQMDETSFTMTFFGQGYSHGT----CVEKNKPNIRICTQVKGPEAGYVA 373
            G F K GP+  QM  +SF+ TFF  GYS          ++ P+ ++  ++ GPEAGYV 
Sbjct: 374 AGLFKKGGPSPAQMKGSSFSWTFFASGYSQKLEDPEAQHEDAPDQKMVVKISGPEAGYVT 195

Query: 374 TPIAMVQAAMTFLSDASDLPKGGGVFTPGAAFSRTKLIDRLNKHGIEFSVI 424
           TPI MVQ+A+  L + S LPK  GV+TP +AF+ T LI+RL+KH ++F V+
Sbjct: 194 TPICMVQSALVILKEKSRLPKEAGVYTPASAFANTSLIERLDKHNVKFQVM 42
>19883
          Length = 412

 Score = 30.4 bits (67), Expect = 1.5,   Method: Composition-based stats.
 Identities = 18/60 (30%), Positives = 28/60 (46%)
 Frame = +1

Query: 36  QSSRLPWAVAGRSKEKLQQVLEKAAQKLGRPSLSSEVGVIICDISNPASLDEMAKQAKLV 95
           Q  R     AGR + +L     +     GRP+++S+ GV  CD+    S D M ++   V
Sbjct: 70  QCGRQLAPAAGRGRPRLH----RGQLDRGRPAVTSQTGVPCCDVIGAPSSDVMVRRRSAV 237
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|7305039|ref|NP_038745.1| B9 protein [Mus musculus]
         (204 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

11539                                                                 130   5e-31
07975                                                                  32   0.21 
>11539
          Length = 459

 Score =  130 bits (326), Expect = 5e-31,   Method: Compositional matrix adjust.
 Identities = 62/88 (70%), Positives = 71/88 (80%)
 Frame = +2

Query: 114 RHKRTIPMFVPESTSTLQKFTSWFMGRRPEYTDPKVVAQGEGREVTRVRSQGFVTLLFNV 173
           RHK  +PMFVPES+S LQK T+WFMGRRPE+ DP+VVAQGEGREVTRVRSQG+V + FNV
Sbjct: 2   RHKIRVPMFVPESSSLLQKLTAWFMGRRPEFVDPRVVAQGEGREVTRVRSQGYVXVSFNV 181

Query: 174 VTKDMKKLGYDTGPVDTQGVLGPSLPQG 201
           V KDMKKLGYD  P D   VL P +P+ 
Sbjct: 182 VMKDMKKLGYDIQPSD---VLNPMVPEN 256
>07975
          Length = 1165

 Score = 31.6 bits (70), Expect = 0.21,   Method: Compositional matrix adjust.
 Identities = 22/79 (27%), Positives = 36/79 (45%), Gaps = 4/79 (5%)
 Frame = +1

Query: 105 AVHVPLSPGRHKRTIPMFVPESTSTLQKFTSWFMGRRPEYTDPKVVAQGEGR----EVTR 160
            + + L   R     P+F   + S L K  SWF+G R +YT   ++     +    + +R
Sbjct: 478 VIQISLMTER-SNLFPIFHMLNVSVLSK*LSWFIGNR*DYTRLMLIHLSAYKL*RWDESR 654

Query: 161 VRSQGFVTLLFNVVTKDMK 179
            + + F T LF  V  +MK
Sbjct: 655 *QFESFYTCLFFKVLYNMK 711
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|149254802|ref|XP_488539.5| PREDICTED: similar to
furry homolog (Drosophila) isoform 1 [Mus musculus]
         (3017 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

22794                                                                  91   7e-31
37075                                                                  33   2.6  
>22794
          Length = 613

 Score = 90.5 bits (223), Expect(2) = 7e-31,   Method: Compositional matrix adjust.
 Identities = 39/85 (45%), Positives = 56/85 (65%)
 Frame = -3

Query: 1125 SQWAGPFSIMFTPLDRYSDRNHQITRYQYCALKAMSAVLCCGPVFDNVGLSPDGYLYKWL 1184
            + W+G FS+ +  LDR  ++    +  +  A+KAMSAVLCCGPVFDN G + DGY+Y WL
Sbjct: 257  ANWSGHFSLTYGTLDRRLNKEESWSEQELSAVKAMSAVLCCGPVFDNNGFNDDGYIYHWL 78

Query: 1185 DNILACQDLRVHQLGCEVVMLLLEL 1209
            D +L+  D +++ L  E V LLL+ 
Sbjct: 77   DTLLSSSDEKIYMLAKETVYLLLDF 3

 Score = 64.3 bits (155), Expect(2) = 7e-31,   Method: Compositional matrix adjust.
 Identities = 34/92 (36%), Positives = 56/92 (60%)
 Frame = -1

Query: 1038 ADAGVISDSTNGALERDTLALGALFLEYVDLTRMLLEAENDKEVEILKDIRAHFSAMVAN 1097
            A+  V   S  GA++ +T  L ++F++Y+D  R  LE END+++ IL++IR HFS  + +
Sbjct: 514  AENKVFGQSEAGAIDTETGQLTSMFVDYIDGARQYLEGENDRDLPILQEIRLHFSCFLQH 335

Query: 1098 LIQCVPVHHRRFLFPQQSLRHHLFILFSQWAG 1129
            LI   P+ +R+ L  ++ LR+ LF L    A 
Sbjct: 334  LINNTPMEYRKTLLSRE-LRYSLFHLLPTGAA 242
>37075
          Length = 630

 Score = 32.7 bits (73), Expect = 2.6,   Method: Composition-based stats.
 Identities = 15/38 (39%), Positives = 21/38 (55%)
 Frame = -3

Query: 2708 FHVFSSLFKNIQKRFCFLTCDAASYLGDNLRGIGSKFV 2745
            F  F + F NI K+  +  CD+ SYLG NL  +  K +
Sbjct: 445  FSSFGAYFVNI*KKLLYNVCDSLSYLGANLLNVLKKCI 332
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|13384652|ref|NP_079573.1| trans-2-enoyl-CoA
reductase, mitochondrial precursor [Mus musculus]
         (373 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

19135                                                                 130   9e-31
25131                                                                  35   1e-05
16326                                                                  30   1.4  
>19135
          Length = 480

 Score =  130 bits (327), Expect = 9e-31,   Method: Compositional matrix adjust.
 Identities = 70/148 (47%), Positives = 92/148 (62%), Gaps = 3/148 (2%)
 Frame = -2

Query: 229 KDLGADYVLTEEELRMPETKTIFK--DLPLPRLALNCVGGKSSTELLRHLAPGGTMVTYG 286
           + LGA  VLTEEELR   T  IFK   L  P L+ NCVGGKS+TE+ RHL  GG MVTYG
Sbjct: 479 ESLGASAVLTEEELR---TTDIFKTGKLKRPILSFNCVGGKSATEVSRHLDNGGVMVTYG 309

Query: 287 GMAKQPVTASVSLLIFKDLKLRGFWLSQW-KKNHSPDEFKELILTLCNLIRQGRLTAPSC 345
           GM+++PVT +   +IFKD+  RGFW+++W K+N S  E +++   +  L+ QG+  AP  
Sbjct: 308 GMSREPVTVATGPIIFKDIAFRGFWMTRWTKENFSAPERQQMFEEIFQLMEQGKFVAPKH 129

Query: 346 SEVPLQGYQQALEASMKPFVSSKQILTM 373
             VPL  ++ A   S   F   K IL M
Sbjct: 128 EMVPLAQFKDAF--SFNGFAGKKFILNM 51
>25131
          Length = 982

 Score = 35.0 bits (79), Expect(2) = 1e-05,   Method: Compositional matrix adjust.
 Identities = 25/77 (32%), Positives = 32/77 (41%)
 Frame = +2

Query: 100 LPAVGGNEGVGQVIAVGSSVSALKPGDWVIPANAGLGTWRTEAVFSEEALIGIPKDIPLQ 159
           LP   G++  G V +VG  V   K GD      +  GT+   AV        +   +   
Sbjct: 2   LPYTPGSDAAGVVESVGXKVKDFKKGDRAYTIRSVTGTYGEYAVSEVVHTARLSDKLSFS 181

Query: 160 SAATLGVNPCTAYRMLV 176
             A LGV   TAYR LV
Sbjct: 182 QGAALGVPYYTAYRALV 232

 Score = 31.2 bits (69), Expect(2) = 1e-05,   Method: Compositional matrix adjust.
 Identities = 32/146 (21%), Positives = 61/146 (41%), Gaps = 5/146 (3%)
 Frame = +3

Query: 180 QLQPGDSVIQNASNSGVGQAVIQIASALRLKTINVVRDRPDIKKLTDRLKDLGADYVLTE 239
           Q +PG++V+ + ++  VG A +QIA A+ L+ +        +    D +K  GA  V   
Sbjct: 240 QNKPGETVLVHGASGAVGLACVQIAKAMGLRVLGTAGTPXGL----DLVKTNGASDVFNH 407

Query: 240 EELRMPETKTIFKDLPLPRLALNCVGGKSSTELLRHLAPGGTMVTYGGMAKQPVTASVSL 299
            E               P + +  +   +    L  +   G +V  G   +  V  +  L
Sbjct: 408 REEGYNANIMAATGGEGPNVIIEMLSNVNLQRDLEMVKFQGRIVVIG--CRGTVEINPRL 581

Query: 300 LIFKDLKLRGFWL-----SQWKKNHS 320
           ++ K+L++ G  L      QW++ H+
Sbjct: 582 MMGKELQVNGVMLPSSTPEQWQEAHA 659
>16326
          Length = 801

 Score = 30.4 bits (67), Expect = 1.4,   Method: Compositional matrix adjust.
 Identities = 15/53 (28%), Positives = 26/53 (49%), Gaps = 2/53 (3%)
 Frame = -3

Query: 129 IPANAGLGTWRTEAV--FSEEALIGIPKDIPLQSAATLGVNPCTAYRMLVDFE 179
           I +N  L  W+   +  F +   + +  DI +Q+  T+  NP    R++ DFE
Sbjct: 304 ISSNRDLNPWKIHGL*RFYQYGFLKVFTDIGVQNRETIAANPAGFCRIVQDFE 146
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|170650630|ref|NP_071877.3| sirtuin 2 isoform 1 [Mus
musculus]
         (389 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

31704                                                                  99   9e-31
29871                                                                  92   3e-19
00656                                                                  45   4e-05
12615                                                                  32   0.34 
00150                                                                  31   0.65 
30688                                                                  31   0.67 
17370                                                                  28   7.8  
>31704
          Length = 314

 Score = 98.6 bits (244), Expect(2) = 9e-31,   Method: Compositional matrix adjust.
 Identities = 45/71 (63%), Positives = 56/71 (78%), Gaps = 1/71 (1%)
 Frame = +1

Query: 128 PEPFFALAKELYP-GQFKPTICHYFIRLLKEKGLLLRCYTQNIDTLERVAGLEPQDLVEA 186
           P PFF LAKELYP G+++P   HYF RLL ++GLLLR YTQNID LER+AG+ P+ +VEA
Sbjct: 97  PRPFFTLAKELYPSGKYRPNYLHYFARLLHDRGLLLRIYTQNIDGLERLAGIPPEKMVEA 276

Query: 187 HGTFYTSHCVN 197
           HGTF ++ CV 
Sbjct: 277 HGTFSSATCVT 309

 Score = 52.8 bits (125), Expect(2) = 9e-31,   Method: Composition-based stats.
 Identities = 21/35 (60%), Positives = 27/35 (77%)
 Frame = +2

Query: 96  FRSPSTGLYANLEKYHLPYPEAIFEISYFKKHPEP 130
           FR+P TGLY NL++Y +PY EAIF+I YF  +P P
Sbjct: 2   FRTPGTGLYDNLQQYSIPYAEAIFDIDYFHHNPAP 106
>29871
          Length = 403

 Score = 92.0 bits (227), Expect = 3e-19,   Method: Compositional matrix adjust.
 Identities = 49/146 (33%), Positives = 77/146 (52%), Gaps = 2/146 (1%)
 Frame = +3

Query: 220 RCEQ--CQSVVKPDIVFFGENLPSRFFSCMQSDFSKVDLLIIMGTSLQVQPFASLISKAP 277
           RC++  C  +VKPDIVFFGE LP RF+  ++ D  + DL+++MGTSL+VQPFA +I    
Sbjct: 3   RCKRTTCHGLVKPDIVFFGEELPKRFYLYLK-DMLQADLVLVMGTSLEVQPFAGIIDTVR 179

Query: 278 LATPRLLINKEKTGQTDPFXXXXXXXXXXXDFDSKKAYRDVAWLGDCDQGCLALADLLGW 337
              PR+L N+   G                 F  +K  +D    GD  +       ++GW
Sbjct: 180 FTIPRVLFNRTAVGP----------------FRRQKRPKDFVAAGDLIEQVEQFVAMVGW 311

Query: 338 KKELEDLVRREHANIDAQSGSQAPNP 363
            +++ D++ R+   ++ +S   AP P
Sbjct: 312 TQDVIDIITRKEDTLNMRSLPLAPAP 389
>00656
          Length = 1026

 Score = 45.4 bits (106), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 35/148 (23%), Positives = 61/148 (41%), Gaps = 7/148 (4%)
 Frame = -3

Query: 145 PTICHYFIRLLKEKGLLLRCYTQNIDTLERVAGLEPQDLVEAHGTFYTSHCVNTSCRKEY 204
           PT  H  +  L + G++    +QN+D L   +G     L E HG  +   C    C  +Y
Sbjct: 985 PTFTHRALVALHKAGIVHYVVSQNVDGLHLRSGFPRDRLSELHGNMFMEQC--NKCHTQY 812

Query: 205 TMGWMKEKIFSEATPR-CEQ------CQSVVKPDIVFFGENLPSRFFSCMQSDFSKVDLL 257
                   +  + T   C Q      C+ ++   ++ +  +LP            K DL 
Sbjct: 811 IRNKCVPTMGEKPTGNPCSQSKTRGLCRGLLHDTVLDWEASLPEHDVDRAYQYSRKADLS 632

Query: 258 IIMGTSLQVQPFASLISKAPLATPRLLI 285
           + +GT+LQ+ P  ++  +    T RL+I
Sbjct: 631 VCLGTTLQIIPSGNIPLETKKNTGRLVI 548
>12615
          Length = 1200

 Score = 32.3 bits (72), Expect = 0.34,   Method: Compositional matrix adjust.
 Identities = 17/44 (38%), Positives = 27/44 (61%), Gaps = 4/44 (9%)
 Frame = +2

Query: 76  CRKVICLVGAGISTSAGIPDFRSPS----TGLYANLEKYHLPYP 115
           CR+      +G ++SA  PDF+SP+    +GLYA  ++ H P+P
Sbjct: 116 CRQDWWQRKSGSTSSA--PDFQSPAPSGVSGLYAEPQQQHTPHP 241
>00150
          Length = 1809

 Score = 31.2 bits (69), Expect = 0.65,   Method: Compositional matrix adjust.
 Identities = 12/38 (31%), Positives = 19/38 (50%)
 Frame = +3

Query: 163 RCYTQNIDTLERVAGLEPQDLVEAHGTFYTSHCVNTSC 200
           R  T NI  +  VAG+ P+ +   +G    +HC+   C
Sbjct: 840 RWNTXNISGIRSVAGVVPKAMNRLYGALAVAHCLTVGC 953
>30688
          Length = 941

 Score = 31.2 bits (69), Expect = 0.67,   Method: Compositional matrix adjust.
 Identities = 11/30 (36%), Positives = 20/30 (66%)
 Frame = +3

Query: 244 FSCMQSDFSKVDLLIIMGTSLQVQPFASLI 273
           F     DF++ D+ +++GT + V PFAS++
Sbjct: 180 FGTSSEDFTEYDVTVLIGTGIGVTPFASIL 269
>17370
          Length = 1066

 Score = 27.7 bits (60), Expect = 7.8,   Method: Compositional matrix adjust.
 Identities = 20/77 (25%), Positives = 33/77 (42%)
 Frame = +1

Query: 152 IRLLKEKGLLLRCYTQNIDTLERVAGLEPQDLVEAHGTFYTSHCVNTSCRKEYTMGWMKE 211
           +R   ++  LL C     D  E+   L+   L      F+    + T C+ E    +MK+
Sbjct: 244 LRRFNDEIALLHCNVY-FDLFEKRLWLKKXSLANCVFNFFKDGII-T*CKFENYQDYMKQ 417

Query: 212 KIFSEATPRCEQCQSVV 228
               + T RCE C++ V
Sbjct: 418 IFGRKVTKRCEHCRTHV 468
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|163792196|ref|NP_058582.3| glutamate receptor,
ionotropic, AMPA3 precursor [Mus musculus]
         (888 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

34285                                                                 131   1e-30
30315                                                                 128   8e-30
14800                                                                  62   1e-09
18672                                                                  39   0.011
28728                                                                  30   4.2  
>34285
          Length = 707

 Score =  131 bits (329), Expect = 1e-30,   Method: Compositional matrix adjust.
 Identities = 59/192 (30%), Positives = 115/192 (59%), Gaps = 3/192 (1%)
 Frame = +1

Query: 601 NSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAA-FLTVERMVS-- 657
           NS  +   +F  QG   +PRS+SGR++   WW F L++I +YTA+L A FL  +  ++  
Sbjct: 100 NSFLYVFSSFTFQGYTAAPRSISGRVLAAFWWIFVLLVIVAYTASLCAIFLHFKPSITSL 279

Query: 658 PIESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWSYMKSAEPSVFTKTTADGVA 717
           P ++ ++L++Q+ +AYG    G T+ + + SK  +  ++W+ + +   +V  +   +G+ 
Sbjct: 280 PFDTFDELSQQSHVAYGIAKGGMTERYLKTSKQPLQRRLWANIHANADAVMVQNIDEGLL 459

Query: 718 RVRKSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSALGTPVNLAVL 777
           RV++ +G FA ++E  + EY+ ++ PCD M +G  L    +G A  +GS + + ++ A+L
Sbjct: 460 RVQQGQGSFALIMEGPLAEYLSEQPPCDXMTLGEELSQHNWGFACQQGSGICSNLSAAIL 639

Query: 778 KLSEQGILDKLK 789
           ++ E+ ++  LK
Sbjct: 640 QMREEELVFDLK 675
>30315
          Length = 336

 Score =  128 bits (322), Expect = 8e-30,   Method: Composition-based stats.
 Identities = 55/105 (52%), Positives = 78/105 (74%)
 Frame = +2

Query: 741 RKPCDTMKVGGNLDSKGYGVATPKGSALGTPVNLAVLKLSEQGILDKLKNKWWYDKGECG 800
           RKPCDT++VGG+L+ +G+G+ATP+GS L   ++ A LK+ E G L +L+ KWWY+KGECG
Sbjct: 2   RKPCDTVRVGGDLNLEGFGIATPQGSELKEMISYATLKMKEDGTLHRLETKWWYEKGECG 181

Query: 801 AKDSGSKDKTSALSLSNVAGVFYILVGGLGLAMMVALIEFCYKSR 845
           +     + K  +LSLSNVAGVFYIL+ GL +A+++ L+E C   R
Sbjct: 182 SDAGHRESKKRSLSLSNVAGVFYILISGLVIAILLGLLEVCLHRR 316
>14800
          Length = 446

 Score = 61.6 bits (148), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 40/147 (27%), Positives = 71/147 (48%), Gaps = 1/147 (0%)
 Frame = +3

Query: 627 VGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYGTLDSGSTKEFFR 686
           V G+WW FT++  +SYTA+LAAFLT      PI S  DLA+Q+ I     +  +    F+
Sbjct: 3   VLGLWWVFTILTTASYTASLAAFLTFSLADVPINSLYDLAQQSHIMPLVKNGTNLYTLFK 182

Query: 687 RSKIAVYEKMWSYMKSAEPSVFTKTTADGVARVRKSKGKFAFLLESTMNEYIEQRKPCDT 746
           +     Y++++  M+    +   K   DG+  V    G +A + +    + + Q+  C+ 
Sbjct: 183 KQGTPTYQRIYEMMQD---TPLVKANEDGMDLVL--SGPYALMSDREQLDLL-QKVDCEN 344

Query: 747 MKVG-GNLDSKGYGVATPKGSALGTPV 772
           +  G    ++ G G +  + +  G  V
Sbjct: 345 LVQGEETFNNNGLGFSCRRATRFGAAV 425
>18672
          Length = 604

 Score = 38.5 bits (88), Expect = 0.011,   Method: Composition-based stats.
 Identities = 14/34 (41%), Positives = 26/34 (76%)
 Frame = +2

Query: 821 VFYILVGGLGLAMMVALIEFCYKSRAESKRMKLT 854
           +FYILV GL L+++  ++EF YK++ +S+R  ++
Sbjct: 2   IFYILVAGLALSVISVVLEFLYKTKVDSRRQNIS 103
>28728
          Length = 465

 Score = 30.0 bits (66), Expect = 4.2,   Method: Composition-based stats.
 Identities = 15/39 (38%), Positives = 19/39 (48%)
 Frame = +3

Query: 417 RTIVVTTILESPYVMYKKNHEQLEGNERYEGYCVDLAYE 455
           R I+VTTIL      Y   H+    N RY  YC  L ++
Sbjct: 123 RRIIVTTILHHHCNDYNNPHDHDHDNHRYHHYCNPLHHD 239
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|22122583|ref|NP_666198.1| phosphodiesterase 6A,
cGMP-specific, rod, alpha [Mus musculus]
         (860 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

28167                                                                 131   1e-30
13617                                                                  53   5e-07
28476                                                                  36   0.084
16973                                                                  32   0.75 
16955                                                                  31   1.6  
>28167
          Length = 587

 Score =  131 bits (329), Expect = 1e-30,   Method: Compositional matrix adjust.
 Identities = 67/146 (45%), Positives = 95/146 (65%)
 Frame = +2

Query: 669 TDLALYFKKRTMFQKIVDQSKTYESTQEWTQYMMLEQTRKEIVMAMMMTACDLSAITKPW 728
           TDLALYF+ R  F    D +K+ E    W+     +   ++++ +MMMTA D++AITKPW
Sbjct: 8   TDLALYFRYRGRF---FDLTKSPEVN--WS-----DDCNRDLLRSMMMTASDVAAITKPW 157

Query: 729 EVQSKVALLVAAEFWEQGDLERTVLQQNPIPMMDRNKADELPKLQVGFIDFVCTFVYKEF 788
           EVQ KVA LV+ EF+EQGD+E+  L+  P+ MMDR K D+LP +QVGFID +C  VY+  
Sbjct: 158 EVQKKVAHLVSREFFEQGDMEKETLKIQPMEMMDREKKDKLPNMQVGFIDTICLPVYEAM 337

Query: 789 SRFHEEITPMLDGITNNRKEWKALAD 814
           +R    ++P+L G   NR  W + A+
Sbjct: 338 TRVSPRLSPLLKGCQQNRDHWMSEAE 415
>13617
          Length = 465

 Score = 53.1 bits (126), Expect = 5e-07,   Method: Compositional matrix adjust.
 Identities = 26/86 (30%), Positives = 43/86 (50%)
 Frame = +2

Query: 383 KNVLSMPIVNKKEEIVGVATFYNRKDGKPFDDMDETLMESLTQFLGWSVLNPDTYESMNK 442
           K +L MPI N   +++GV    N+ D   F+  DE L E+   F G  + N   YE+  K
Sbjct: 80  KCILCMPIKNVAGKVIGVMQLINKLDNTAFNKNDENLFEAFAIFCGMGINNTSMYETAMK 259

Query: 443 LENRKDIFQDIVKYHVKCDNEEIQKI 468
              ++ +  +++ YH     EE +K+
Sbjct: 260 AIAKQRVALEVMSYHAMAPMEEAEKL 337
>28476
          Length = 1475

 Score = 35.8 bits (81), Expect = 0.084,   Method: Composition-based stats.
 Identities = 16/57 (28%), Positives = 30/57 (52%)
 Frame = -3

Query: 518 LVKCGIQMYYELRVVDKFHIPQEALVRFMYSLSKGYRRITYHNWRHGFNVGQTMFSL 574
           L K   +++ E+ +++ F IP    + + ++L  GYR   YHN  H  +V   ++ L
Sbjct: 201 LSKVAYKLFTEVGLMETFRIPVVEFINYFHALELGYREKPYHNRVHATDVLHGVYYL 31
>16973
          Length = 1511

 Score = 32.3 bits (72), Expect = 0.75,   Method: Compositional matrix adjust.
 Identities = 23/75 (30%), Positives = 37/75 (49%), Gaps = 1/75 (1%)
 Frame = +2

Query: 733  KVALLVAAEFWEQGDLERTVLQQNPIP-MMDRNKADELPKLQVGFIDFVCTFVYKEFSRF 791
            +VA LV+   WE     R   ++NP+  +    KA    +           F+ +EFSRF
Sbjct: 956  RVASLVS---WE--SFYRKRKEKNPVSRLFVFRKARYFSRFS--------NFILREFSRF 1096

Query: 792  HEEITPMLDGITNNR 806
            H++ITP++    +NR
Sbjct: 1097 HKQITPLIVRHQSNR 1141
>16955
          Length = 862

 Score = 31.2 bits (69), Expect = 1.6,   Method: Composition-based stats.
 Identities = 12/24 (50%), Positives = 19/24 (79%)
 Frame = +1

Query: 783 FVYKEFSRFHEEITPMLDGITNNR 806
           F+ +EFSRFH++ITP++    +NR
Sbjct: 640 FILREFSRFHKQITPLIVRHQSNR 711
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|30794470|ref|NP_079822.1| ribosomal L1 domain
containing 1 [Mus musculus]
         (452 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

10829                                                                 130   1e-30
16617                                                                  37   0.015
32534                                                                  29   4.7  
>10829
          Length = 1878

 Score =  130 bits (327), Expect = 1e-30,   Method: Compositional matrix adjust.
 Identities = 69/199 (34%), Positives = 115/199 (57%), Gaps = 3/199 (1%)
 Frame = -3

Query: 70   LWKIPEKELRVKVPLPHSILSESSDVCLFTKDEFDSPEQTEG---FYKKLLKKHGVNTIS 126
            L K+   ++ +K+ LP+ +     + CLF KD   S  + E     +K+ LK+ G+  IS
Sbjct: 1684 LKKVVTSKINIKLKLPNGLEGIKKEACLFVKDLDRSDREHEKXTRHFKQKLKEEGITCIS 1505

Query: 127  QIIPFKTLKTEYKAYEAKLRLLGSFEVFITDARIRRHLPSHIGRHFYQRKKVPVSVNLLA 186
            QIIP K LK EYK +EAK +L  S++VF  D RI R LP+++G+ FY RK+ P+ V + +
Sbjct: 1504 QIIPLKALKLEYKPFEAKXKLSDSYDVFWADXRIIRLLPAYLGKAFYGRKRHPIQVRMDS 1325

Query: 187  KNLSKEINRCITGTVLNISKRGSCSTIRIGHTGMETEHIVDNILAVSEMLSEKLPEKWQS 246
            K+L +E    I+ +   +S +GS     +G T M    +V NI A    ++  +P    +
Sbjct: 1324 KDLREEFETAISNSRCLLSGKGSSGMATVGSTDMSAAELVQNITACMHQIAAAIPGGAVN 1145

Query: 247  VKLLFLKTEKSVSLPIFSS 265
            ++ + +KTE S+++P++ S
Sbjct: 1144 IRNMHIKTEDSMAIPVYLS 1088
>16617
          Length = 1179

 Score = 37.0 bits (84), Expect = 0.015,   Method: Compositional matrix adjust.
 Identities = 18/62 (29%), Positives = 31/62 (50%)
 Frame = -1

Query: 206 KRGSCSTIRIGHTGMETEHIVDNILAVSEMLSEKLPEKWQSVKLLFLKTEKSVSLPIFSS 265
           K+  C +  +GH GM  + +  NI      L   L + WQ+V+ L++K+    +  IF +
Sbjct: 354 KKVLCLSTCVGHVGMSQDDLYSNITLAINFLVSLLKKNWQNVRALYVKSTMGKAQRIF*T 175

Query: 266 FV 267
            V
Sbjct: 174 LV 169
>32534
          Length = 388

 Score = 28.9 bits (63), Expect = 4.7,   Method: Composition-based stats.
 Identities = 16/34 (47%), Positives = 21/34 (61%)
 Frame = -3

Query: 171 HFYQRKKVPVSVNLLAKNLSKEINRCITGTVLNI 204
           +FY  KKV ++ N+L  NL K  N CI   VLN+
Sbjct: 197 YFYSDKKV-ITGNILHSNLLK*WNACIRTHVLNV 99
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|33620739|ref|NP_034990.1| myosin, light polypeptide
6, alkali, smooth muscle and non-muscle [Mus musculus]
         (151 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

14594                                                                 128   1e-30
11425                                                                 103   4e-23
26610                                                                  73   4e-14
14366                                                                  70   3e-13
20251                                                                  67   3e-12
05237                                                                  67   4e-12
38338                                                                  64   2e-11
01019                                                                  61   2e-10
18171                                                                  58   2e-09
22063                                                                  57   4e-09
14945                                                                  57   4e-09
17484                                                                  49   7e-07
08108                                                                  37   0.005
01491                                                                  35   0.013
01401                                                                  34   0.024
16255                                                                  33   0.035
01773                                                                  33   0.051
24688                                                                  32   0.080
19942                                                                  29   0.71 
13977                                                                  28   1.3  
25423                                                                  27   3.2  
15966                                                                  27   3.3  
05230                                                                  27   3.8  
13028                                                                  26   8.3  
>14594
          Length = 1014

 Score =  128 bits (321), Expect = 1e-30,   Method: Compositional matrix adjust.
 Identities = 71/146 (48%), Positives = 93/146 (63%), Gaps = 1/146 (0%)
 Frame = +3

Query: 4   FTEDQTAEFKEAFQLFDRTGDGKILYSQCGDVMRALGQNPTNAEVLKVLGNPKSDEMNVK 63
            T++Q AEFKEAF LFD+ GDG I  S+ G VMR+LGQNPT  E+  ++    +D     
Sbjct: 423 LTDEQVAEFKEAFSLFDKDGDGTITTSELGTVMRSLGQNPTENELQDMINEVDAD--GNG 596

Query: 64  VLDFEHFLPMLQTVAKNKDQGTYEDYVEGLRVFDKEGNGTVMGAEIRHVLVTLGEKMTEE 123
            +DFE FL M+    K KD    E+  E  RVFDK+GNG +  AE+RHV+  LGEK+T+E
Sbjct: 597 TIDFEEFLHMM--ARKMKDTDCEEELREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDE 770

Query: 124 EV-EMLVAGHEDSNGCINYEELVRMV 148
           EV EM+     D +G +NYEE V M+
Sbjct: 771 EVDEMIKEADLDGDGMVNYEEFVTMM 848
>11425
          Length = 599

 Score =  103 bits (256), Expect = 4e-23,   Method: Compositional matrix adjust.
 Identities = 57/156 (36%), Positives = 89/156 (57%), Gaps = 5/156 (3%)
 Frame = -2

Query: 1   MCDFTEDQTAEFKEAFQLFDRTG--DGKILYSQCGDVMRALGQNPTNAEVLKVLGNPKSD 58
           M   ++    +  E F+LFD     DG +   + GD+   LG NPT   + K  G  K  
Sbjct: 586 MXSLSKSDIEDITEVFELFDFWDGRDGDVDAFKVGDMCFCLGLNPTQEIIRKNGGTTKLG 407

Query: 59  EMNVKVLDFEHFLPMLQTVAKNKDQGTYEDYVEGLRVFDKEGNGTVMGAEIRHVLVTLGE 118
           E   K+   E FLP+ +T++K KD GT+ D++EG + FD+EG G +  AE+RH+L  LGE
Sbjct: 406 EKAYKL---EEFLPIYETISKEKDTGTFADFMEGFKTFDREGQGFISAAELRHLLTGLGE 236

Query: 119 KMTEEEVEMLVAG---HEDSNGCINYEELVRMVLNG 151
           +++++EV+ L+      ED  G + YE+ ++ VL G
Sbjct: 235 RLSDDEVDELIKATDTREDLEGNVKYEDFIQKVLKG 128
>26610
          Length = 455

 Score = 73.2 bits (178), Expect = 4e-14,   Method: Compositional matrix adjust.
 Identities = 47/137 (34%), Positives = 74/137 (54%), Gaps = 2/137 (1%)
 Frame = +3

Query: 14  EAFQLFDRTGDGKILYSQCGDVMRALGQNPTNAEVLKVLGNPKSDEM-NVKVLDFEHFLP 72
           EAF+LFD   DGKI  S+ G  +R+LG   T++++ ++L     +    V +  F   + 
Sbjct: 54  EAFELFDTDNDGKIAASEVGTAIRSLGHVVTDSDLRRLLSKAGIEPHGKVDMNRFRQLVQ 233

Query: 73  MLQTVAKNKDQGTYEDYVEGLRVFDKEGNGTVMGAEIRHVLVTLGEKMTEEEVEMLVAGH 132
            LQ V   K         E     DKEG+G VM  E+RH+L  +G+++T+EE   L+   
Sbjct: 234 PLQGVNYTKQ------LDEAFNTIDKEGSGFVMATELRHLLTHMGDRITDEEFNALLEEL 395

Query: 133 E-DSNGCINYEELVRMV 148
           E DSNG +  +E V+++
Sbjct: 396 EVDSNGRVRRKEFVQLL 446
>14366
          Length = 499

 Score = 70.5 bits (171), Expect = 3e-13,   Method: Compositional matrix adjust.
 Identities = 46/142 (32%), Positives = 82/142 (57%), Gaps = 1/142 (0%)
 Frame = -3

Query: 11  EFKEAFQLFDRTGDGKILYSQCGDVMRALGQNPTNAEVLKVLGNPKSDEMNVKVLDFEHF 70
           E +EAF + + + D  I  ++ G V+R++G+ PT ++ LK L   + +    + L  +  
Sbjct: 464 ELQEAF-IMNCSPDNTIALNKLGIVVRSIGRAPTESQ-LKTL-TMEFENRGKRTLTLQEV 294

Query: 71  LPMLQTVAKNKDQGTYEDYVEGLRVFDKEGNGTVMGAEIRHVLVTLGEKMTEEEV-EMLV 129
           + ++       +  T ++  E  R+FDKEGNG +  AE+RHVL  LGEK+++EEV EM+ 
Sbjct: 293 IAIVTKYEFAPE--TSDNLREAFRIFDKEGNGMINAAELRHVLTHLGEKLSDEEVDEMIR 120

Query: 130 AGHEDSNGCINYEELVRMVLNG 151
                 +G ++Y + V+++ NG
Sbjct: 119 EADISGDGQVSYNDFVKVMENG 54

 Score = 32.0 bits (71), Expect = 0.094,   Method: Compositional matrix adjust.
 Identities = 14/46 (30%), Positives = 28/46 (60%)
 Frame = -3

Query: 3   DFTEDQTAEFKEAFQLFDRTGDGKILYSQCGDVMRALGQNPTNAEV 48
           +F  + +   +EAF++FD+ G+G I  ++   V+  LG+  ++ EV
Sbjct: 272 EFAPETSDNLREAFRIFDKEGNGMINAAELRHVLTHLGEKLSDEEV 135
>20251
          Length = 2203

 Score = 67.0 bits (162), Expect = 3e-12,   Method: Compositional matrix adjust.
 Identities = 42/149 (28%), Positives = 73/149 (48%), Gaps = 1/149 (0%)
 Frame = +3

Query: 4   FTEDQTAEFKEAFQLFDRTGDGKILYSQCGDVMRALGQNPTNAEVLKVLGNPKSDEMNVK 63
           F + Q  EFKEAF + D+  DG I     GD++ +LG+NPT  ++ +++           
Sbjct: 141 FDQSQIQEFKEAFNMIDQNRDGFIDKEDLGDMLASLGKNPTEGQLDEMMNXAPG------ 302

Query: 64  VLDFEHFLPMLQTVAKNKDQGTYEDYVE-GLRVFDKEGNGTVMGAEIRHVLVTLGEKMTE 122
            ++F  FL M        D    ED ++     FD++G G +    +R +L T+G++ T+
Sbjct: 303 PINFTMFLTMFGDKLNGTDP---EDVIKNAFACFDEDGKGVIQEDRLRELLTTMGDRFTD 473

Query: 123 EEVEMLVAGHEDSNGCINYEELVRMVLNG 151
           +EV+ +        G  +Y E  R++  G
Sbjct: 474 DEVDEMFRDAPIKRGNFDYLEFTRILKYG 560
>05237
          Length = 472

 Score = 66.6 bits (161), Expect = 4e-12,   Method: Compositional matrix adjust.
 Identities = 33/69 (47%), Positives = 48/69 (69%), Gaps = 1/69 (1%)
 Frame = +3

Query: 81  KDQGTYEDYVEGLRVFDKEGNGTVMGAEIRHVLVTLGEKMTEEEV-EMLVAGHEDSNGCI 139
           K+  T ++  E  RVFDK+GNG +  +E+RHV+  LGEK+T+EEV EM+     D +G +
Sbjct: 9   KETDTDDELREAFRVFDKDGNGFISASELRHVMTNLGEKLTDEEVDEMIREADIDGDGQV 188

Query: 140 NYEELVRMV 148
           NYEE V+M+
Sbjct: 189 NYEEFVKMM 215

 Score = 38.1 bits (87), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 23/70 (32%), Positives = 39/70 (55%)
 Frame = +3

Query: 7  DQTAEFKEAFQLFDRTGDGKILYSQCGDVMRALGQNPTNAEVLKVLGNPKSDEMNVKVLD 66
          D   E +EAF++FD+ G+G I  S+   VM  LG+  T+ EV +++     D      ++
Sbjct: 18 DTDDELREAFRVFDKDGNGFISASELRHVMTNLGEKLTDEEVDEMIREADID--GDGQVN 191

Query: 67 FEHFLPMLQT 76
          +E F+ M+ T
Sbjct: 192YEEFVKMMTT 221
>38338
          Length = 463

 Score = 64.3 bits (155), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 32/59 (54%), Positives = 40/59 (67%), Gaps = 1/59 (1%)
 Frame = -2

Query: 1   MCD-FTEDQTAEFKEAFQLFDRTGDGKILYSQCGDVMRALGQNPTNAEVLKVLGNPKSD 58
           M D  TE+Q AEFKEAF LFD+ GDG I   + G VMR+LGQNPT AE+  ++    +D
Sbjct: 198 MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDAD 22

 Score = 38.1 bits (87), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 26/73 (35%), Positives = 43/73 (58%), Gaps = 6/73 (8%)
 Frame = -2

Query: 75  QTVAKNK--DQGTYE---DYVEGLRVFDKEGNGTVMGAEIRHVLVTLGEKMTEEEVE-ML 128
           QT +K+   DQ T E   ++ E   +FDK+G+GT+   E+  V+ +LG+  TE E++ M+
Sbjct: 219 QTHSKSNMADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMI 40

Query: 129 VAGHEDSNGCINY 141
                D NG I++
Sbjct: 39  NEVDADGNGTIDF 1
>01019
          Length = 1705

 Score = 61.2 bits (147), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 31/57 (54%), Positives = 41/57 (71%), Gaps = 1/57 (1%)
 Frame = +1

Query: 93  LRVFDKEGNGTVMGAEIRHVLVTLGEKMTEEEV-EMLVAGHEDSNGCINYEELVRMV 148
           L VFDK+GNG +  AE+RHV+  LGEK+T+EEV EM+     D +G +NYEE V M+
Sbjct: 37  LLVFDKDGNGFISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVTMM 207
>18171
          Length = 1131

 Score = 57.8 bits (138), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 30/88 (34%), Positives = 54/88 (61%), Gaps = 2/88 (2%)
 Frame = +3

Query: 65  LDFEHFLPMLQTVAKNKDQGTYED-YVEGLRVFDKEGNGTVMGAEIRHVLVTLGEKMTEE 123
           +DF  FL ++     +KD    +D  +E L + DK+  G +  A +RHVL TLG+++T E
Sbjct: 96  VDFPDFLTLMARTVGSKDPQEEDDAMLEALTLLDKDQTGVISTALLRHVLTTLGDQLTSE 275

Query: 124 EVEMLVA-GHEDSNGCINYEELVRMVLN 150
           EVE L+    ++  G ++Y+E ++M+++
Sbjct: 276 EVEELIKEADKEETGQVDYKEFIKMMMS 359
>22063
          Length = 688

 Score = 56.6 bits (135), Expect = 4e-09,   Method: Compositional matrix adjust.
 Identities = 36/118 (30%), Positives = 56/118 (47%)
 Frame = +3

Query: 2   CDFTEDQTAEFKEAFQLFDRTGDGKILYSQCGDVMRALGQNPTNAEVLKVLGNPKSDEMN 61
           C+ TE+Q  E +EAF LFD  G G I   +    MRALG  P   E+ K++   + D+  
Sbjct: 147 CELTEEQKQEIREAFDLFDADGSGTIDAKELKVAMRALGFEPKKEEIKKMIA--EIDKEG 320

Query: 62  VKVLDFEHFLPMLQTVAKNKDQGTYEDYVEGLRVFDKEGNGTVMGAEIRHVLVTLGEK 119
              +DF  FL ++      KD    E+ ++  R+FD +  G  +  +       +G K
Sbjct: 321 TGTIDFNDFLTIMTQKMSEKD--AKEEILKAFRLFDDDETGKNLFPQFETSRKRIGRK 488

 Score = 30.0 bits (66), Expect = 0.36,   Method: Compositional matrix adjust.
 Identities = 14/59 (23%), Positives = 35/59 (59%), Gaps = 1/59 (1%)
 Frame = +3

Query: 91  EGLRVFDKEGNGTVMGAEIRHVLVTLGEKMTEEEVEMLVAG-HEDSNGCINYEELVRMV 148
           E   +FD +G+GT+   E++  +  LG +  +EE++ ++A   ++  G I++ + + ++
Sbjct: 183 EAFDLFDADGSGTIDAKELKVAMRALGFEPKKEEIKKMIAEIDKEGTGTIDFNDFLTIM 359
>14945
          Length = 1337

 Score = 56.6 bits (135), Expect = 4e-09,   Method: Compositional matrix adjust.
 Identities = 34/101 (33%), Positives = 51/101 (50%)
 Frame = +1

Query: 2   CDFTEDQTAEFKEAFQLFDRTGDGKILYSQCGDVMRALGQNPTNAEVLKVLGNPKSDEMN 61
           C+ TE+Q  E +EAF LFD  G G I   +    MRALG  P   E+ K++   + D+  
Sbjct: 88  CELTEEQKQEIREAFDLFDADGSGTIDAKELKVAMRALGFEPKKEEIKKMIA--EIDKEG 261

Query: 62  VKVLDFEHFLPMLQTVAKNKDQGTYEDYVEGLRVFDKEGNG 102
              +DF  FL ++      KD    E+ ++  R+FD +  G
Sbjct: 262 TGTIDFNDFLTIMTQKMSEKD--AKEEILKAFRLFDDDETG 378

 Score = 30.8 bits (68), Expect = 0.24,   Method: Compositional matrix adjust.
 Identities = 14/59 (23%), Positives = 35/59 (59%), Gaps = 1/59 (1%)
 Frame = +1

Query: 91  EGLRVFDKEGNGTVMGAEIRHVLVTLGEKMTEEEVEMLVAG-HEDSNGCINYEELVRMV 148
           E   +FD +G+GT+   E++  +  LG +  +EE++ ++A   ++  G I++ + + ++
Sbjct: 124 EAFDLFDADGSGTIDAKELKVAMRALGFEPKKEEIKKMIAEIDKEGTGTIDFNDFLTIM 300
>17484
          Length = 471

 Score = 48.9 bits (115), Expect = 7e-07,   Method: Compositional matrix adjust.
 Identities = 23/82 (28%), Positives = 46/82 (56%), Gaps = 1/82 (1%)
 Frame = -3

Query: 68  EHFLPMLQTVAKNKDQGTYEDYVEGLRVFDKEGNGTVMGAEIRHVLVTLGEKMTEEEVEM 127
           E FLP++    K   +   E   +  R FD+ G+G +  +E+R  +  +G+K+++ +VE 
Sbjct: 325 EEFLPLIVGRMKGGSEKDKE-MRDAFRAFDQNGDGVISISELRQAMAKMGQKLSDADVES 149

Query: 128 LVAG-HEDSNGCINYEELVRMV 148
           ++    +D +G +NYEE  + +
Sbjct: 148 IIRDVDKDGDGFVNYEEFTKFI 83

 Score = 34.3 bits (77), Expect = 0.024,   Method: Compositional matrix adjust.
 Identities = 15/42 (35%), Positives = 26/42 (61%)
 Frame = -3

Query: 11  EFKEAFQLFDRTGDGKILYSQCGDVMRALGQNPTNAEVLKVL 52
           E ++AF+ FD+ GDG I  S+    M  +GQ  ++A+V  ++
Sbjct: 268 EMRDAFRAFDQNGDGVISISELRQAMAKMGQKLSDADVESII 143
>08108
          Length = 818

 Score = 36.6 bits (83), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 17/55 (30%), Positives = 33/55 (60%), Gaps = 1/55 (1%)
 Frame = +2

Query: 95  VFDKEGNGTVMGAEIRHVLVTLGEKMTEEEVEMLVAGHE-DSNGCINYEELVRMV 148
           VFD +G+G++   E+   L   G  +T+++   L+  ++ DSNG I+ +E  ++V
Sbjct: 149 VFDTDGSGSISAGELGEALRAQGADITDDQTAELIKKYDSDSNGDIDTDEFRKLV 313
>01491
          Length = 1707

 Score = 35.0 bits (79), Expect = 0.013,   Method: Compositional matrix adjust.
 Identities = 15/41 (36%), Positives = 27/41 (65%)
 Frame = +2

Query: 86  YEDYVEGLRVFDKEGNGTVMGAEIRHVLVTLGEKMTEEEVE 126
           Y D  +   +FDK+GNGTV   E+ +V  +LG ++ +E+++
Sbjct: 125 YNDASQTFHLFDKKGNGTVSTKELANVFKSLGLQVEDEKLK 247

 Score = 26.9 bits (58), Expect = 3.1,   Method: Compositional matrix adjust.
 Identities = 11/37 (29%), Positives = 20/37 (54%)
 Frame = +2

Query: 4   FTEDQTAEFKEAFQLFDRTGDGKILYSQCGDVMRALG 40
            TE    +  + F LFD+ G+G +   +  +V ++LG
Sbjct: 110 ITEKMYNDASQTFHLFDKKGNGTVSTKELANVFKSLG 220
>01401
          Length = 1454

 Score = 33.9 bits (76), Expect = 0.024,   Method: Compositional matrix adjust.
 Identities = 28/106 (26%), Positives = 56/106 (52%), Gaps = 2/106 (1%)
 Frame = +1

Query: 47  EVLKVLGNPKSDEMNVKVLDFEHFLPMLQTVAKNKDQGTYEDYVEGLRVFDKEGNGTVMG 106
           ++L  L     DE    V+D+E FL ++      ++  T   +V   R  DK+ +G++  
Sbjct: 172 QLLTALDKDSKDE----VIDYEEFLRVMGM----QEAATVMAHV--FRQLDKDNSGSLTR 321

Query: 107 AEIRHVLVTLGE-KMTEEEV-EMLVAGHEDSNGCINYEELVRMVLN 150
            EI   + + GE K+   ++ ++LVA H+D++  ++Y E V++ + 
Sbjct: 322 EEIMAAVQSEGELKLRAAKISDLLVAWHKDADQKLDYNEFVQVWIK 459
>16255
          Length = 767

 Score = 33.5 bits (75), Expect = 0.035,   Method: Compositional matrix adjust.
 Identities = 18/37 (48%), Positives = 25/37 (67%), Gaps = 1/37 (2%)
 Frame = -2

Query: 113 LVTLGEKMTEEEV-EMLVAGHEDSNGCINYEELVRMV 148
           +  LGEK+T+EEV EM+     D +G +NYEE V M+
Sbjct: 766 MTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVTMM 656
>01773
          Length = 1950

 Score = 33.1 bits (74), Expect = 0.051,   Method: Compositional matrix adjust.
 Identities = 30/141 (21%), Positives = 65/141 (46%), Gaps = 4/141 (2%)
 Frame = +1

Query: 9   TAEFKEAFQLFDRTGDGKILYSQCGDVMRALGQNPTNAEVLKVL---GNPKSDEMNVKVL 65
           T  +K+ F+  D+  DG +   +  ++ +  G + +++++         P+ D    K +
Sbjct: 151 TDAYKQLFKEADKNNDGYLEIKELRELFKRNGSSLSDSQIADTFVFFDGPRGD----KRI 318

Query: 66  DFEHFLPMLQTVAKNKDQGTYEDYVEGLRVFDKEGNGTVMGAEIRHVLVTLGEKMTEEEV 125
            FE F   L  +         +   E  +  DK G+G +   E++ +L   G+K T ++V
Sbjct: 319 TFEXFCKGLDQIVM-----FVQKLAELFKAKDKSGDGYLDRDELKALLDESGQKFTADDV 483

Query: 126 E-MLVAGHEDSNGCINYEELV 145
             +L +  ++++  I +EE V
Sbjct: 484 SAILKSADKNNDNKICFEEFV 546
>24688
          Length = 1057

 Score = 32.3 bits (72), Expect = 0.080,   Method: Compositional matrix adjust.
 Identities = 14/19 (73%), Positives = 17/19 (89%)
 Frame = -2

Query: 133  EDSNGCINYEELVRMVLNG 151
            EDS+G INYEEL++MV NG
Sbjct: 1053 EDSHGNINYEELIKMVRNG 997
>19942
          Length = 367

 Score = 29.3 bits (64), Expect = 0.71,   Method: Compositional matrix adjust.
 Identities = 15/32 (46%), Positives = 22/32 (68%), Gaps = 1/32 (3%)
 Frame = +2

Query: 112 VLVTLGEKMTEEEV-EMLVAGHEDSNGCINYE 142
           V+  LGEK+T+EEV EM+     D +G +NY+
Sbjct: 2   VMTNLGEKLTDEEVDEMIREADIDGDGQVNYD 97
>13977
          Length = 634

 Score = 28.5 bits (62), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 12/30 (40%), Positives = 21/30 (70%)
 Frame = +1

Query: 97  DKEGNGTVMGAEIRHVLVTLGEKMTEEEVE 126
           D+E +  +  AEIRH+ + L +KM E+E++
Sbjct: 262 DQETHSAIEEAEIRHLELQLQKKMFEQELQ 351
>25423
          Length = 448

 Score = 26.9 bits (58), Expect = 3.2,   Method: Compositional matrix adjust.
 Identities = 11/33 (33%), Positives = 18/33 (54%)
 Frame = +3

Query: 115 TLGEKMTEEEVEMLVAGHEDSNGCINYEELVRM 147
           TL   +T   V +L+   E+  GC+   E++RM
Sbjct: 207 TLPACLTPHRVTLLLRHEEEEPGCLRANEIIRM 305
>15966
          Length = 362

 Score = 26.9 bits (58), Expect = 3.3,   Method: Compositional matrix adjust.
 Identities = 19/76 (25%), Positives = 39/76 (51%), Gaps = 15/76 (19%)
 Frame = +2

Query: 85  TYEDYVEGL--------------RVFDKEGNGTVMGAEIRHVLVTLGEKMTEEEVE-MLV 129
           T+E++ +GL              +  DK G+G +   E++ +L   G+K T ++V  +L 
Sbjct: 86  TFEEFCKGLDQIVMFVQKLAELFKAKDKSGDGYLDRDELKALLDESGQKFTADDVSAILK 265

Query: 130 AGHEDSNGCINYEELV 145
           +  ++++  I +EE V
Sbjct: 266 SADKNNDNKICFEEFV 313
>05230
          Length = 843

 Score = 26.9 bits (58), Expect = 3.8,   Method: Compositional matrix adjust.
 Identities = 28/126 (22%), Positives = 54/126 (42%)
 Frame = -2

Query: 24  DGKILYSQCGDVMRALGQNPTNAEVLKVLGNPKSDEMNVKVLDFEHFLPMLQTVAKNKDQ 83
           DG++   +   +M  LG  P   E  KVL + K  ++    L  E ++ ++   + +   
Sbjct: 815 DGRLNLFEFTRLMTLLGL-PNAQEAAKVLFD-KQTKVERDRLRMEEYISIMSDASVDMKT 642

Query: 84  GTYEDYVEGLRVFDKEGNGTVMGAEIRHVLVTLGEKMTEEEVEMLVAGHEDSNGCINYEE 143
             +         FD +G+G     ++   L  +G  +T +    + A   + +G INY +
Sbjct: 641 NMWRKLFAQ---FDTDGSGWASREDVIEGLENIGITITPDLRAKIKAMDGNKDGKINYAD 471

Query: 144 LVRMVL 149
            +RM L
Sbjct: 470 FLRMQL 453
>13028
          Length = 1273

 Score = 25.8 bits (55), Expect = 8.3,   Method: Compositional matrix adjust.
 Identities = 33/109 (30%), Positives = 45/109 (41%), Gaps = 10/109 (9%)
 Frame = -1

Query: 27   ILYSQCGDVMRALGQNPTNAEVLKVLGNPKSDEM-----NVKVLDFEHFLPMLQTVAKNK 81
            I  S+   VMRALG  PT  E+  +L   K          V+ LD   F+ +   V    
Sbjct: 1060 IPLSEVPFVMRALGFYPTEQEIEDMLNEVKFSRYVETGQYVEELDLGTFIKLY--VNHRP 887

Query: 82   DQGTYEDYVEGLRVFDKEG-----NGTVMGAEIRHVLVTLGEKMTEEEV 125
              G   D ++    FD  G      G V   E+  +L + GE MTE E+
Sbjct: 886  AFGLSPDKLQ--WAFDTLGMPSPAGGAVDRGELLDILQSKGEHMTEYEL 746
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|46402177|ref|NP_997097.1| exocyst complex component 5
[Mus musculus]
         (708 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

38155                                                                 112   1e-30
25731                                                                  64   2e-10
08856                                                                  30   3.7  
08302                                                                  30   4.3  
28007                                                                  30   4.5  
>38155
          Length = 572

 Score =  112 bits (280), Expect(3) = 1e-30,   Method: Compositional matrix adjust.
 Identities = 53/88 (60%), Positives = 69/88 (78%), Gaps = 1/88 (1%)
 Frame = +3

Query: 621 YSYSCMGGMLAICDVAEYRKCAKD-FKIPMVLHLFDTLHALCNLLVVAPDNLKQVCSGEQ 679
           +S + +G ML ICDV EYRKC K+  +IP++  LF+ LHALCNLLVV P+NLK V +GEQ
Sbjct: 168 FSTTPLGAMLVICDVNEYRKCVKEEMRIPIITQLFERLHALCNLLVVVPENLKVVRTGEQ 347

Query: 680 LANLDKNILHSFVQLRADYRSARLARHF 707
           LA+LD  ++ +FVQLRADYRSAR+A + 
Sbjct: 348 LADLDDTMIINFVQLRADYRSARIANYM 431

 Score = 36.6 bits (83), Expect(3) = 1e-30,   Method: Composition-based stats.
 Identities = 19/43 (44%), Positives = 27/43 (62%), Gaps = 2/43 (4%)
 Frame = +1

Query: 573 TNACVKVCVYVRKQVEKIKNSMDGKNVDTVLMELGVRF--HRL 613
           T AC KV   +   V  +++S+DG+NV+  L ELG RF  HR+
Sbjct: 22  TAACSKVVRSLNTHVRSMRSSLDGQNVEIGLTELGKRFSPHRV 150

 Score = 23.1 bits (48), Expect(3) = 1e-30,   Method: Composition-based stats.
 Identities = 7/17 (41%), Positives = 12/17 (70%)
 Frame = +2

Query: 610 FHRLIYEHLQQYSYSCM 626
           FHR +YEH+  + Y+ +
Sbjct: 134 FHRTVYEHILGFQYNSI 184
>25731
          Length = 427

 Score = 63.9 bits (154), Expect = 2e-10,   Method: Composition-based stats.
 Identities = 35/102 (34%), Positives = 57/102 (55%)
 Frame = +2

Query: 478 ANLYFLDVVQQANTIFHLFDKQFNDHLMPLISSSPKLSECXXXXXXXXXXXXXXXDTGID 537
           + + FL    +AN I HL DK  N  ++P +S++PK S+                D G+D
Sbjct: 101 STIIFL*CGPKANIIVHLLDKLCNSAVIPCVSNTPKYSDYVFKKRILMEQIETKLDQGLD 280

Query: 538 RTLNCMIGQMKHILAAEQKKTDFKPEDENNVLIQYTNACVKV 579
           R+++ +IG +K  L  EQKKTD+KPE + + +   + AC++V
Sbjct: 281 RSISAVIGWVKVYLQYEQKKTDYKPETDVDTI--SSAACLQV 400

 Score = 43.5 bits (101), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 21/41 (51%), Positives = 28/41 (68%), Gaps = 1/41 (2%)
 Frame = +3

Query: 449 ILVEFLCIEHIDYALETGLAGIPSSDSR-NANLYFLDVVQQ 488
           IL+ FL  EH+DYALE GL  +P ++ +    LYF DVVQ+
Sbjct: 12  ILLRFLMHEHVDYALELGLQAMPLAEGKVFPQLYFFDVVQK 134
>08856
          Length = 1056

 Score = 30.0 bits (66), Expect = 3.7,   Method: Compositional matrix adjust.
 Identities = 19/61 (31%), Positives = 28/61 (45%)
 Frame = +3

Query: 536 IDRTLNCMIGQMKHILAAEQKKTDFKPEDENNVLIQYTNACVKVCVYVRKQVEKIKNSMD 595
           I+ T NC IG    +LA         PE    +LI Y   C+K C +  +     K+++D
Sbjct: 585 INITFNCTIG----VLAKVNNNKSLCPEGMIWILIYYYGFCIKHCAFDAEY--DFKSTID 746

Query: 596 G 596
           G
Sbjct: 747 G 749
>08302
          Length = 2000

 Score = 29.6 bits (65), Expect = 4.3,   Method: Compositional matrix adjust.
 Identities = 15/46 (32%), Positives = 23/46 (50%)
 Frame = -3

Query: 538 RTLNCMIGQMKHILAAEQKKTDFKPEDENNVLIQYTNACVKVCVYV 583
           R+L+C+    KH+       + F P  E   + +Y  AC+  CVYV
Sbjct: 858 RSLSCL---QKHVNCKTSALSIFTPSTEKLCVCRYMCACMSGCVYV 730
>28007
          Length = 644

 Score = 29.6 bits (65), Expect = 4.5,   Method: Compositional matrix adjust.
 Identities = 15/49 (30%), Positives = 26/49 (53%)
 Frame = +1

Query: 294 ECRKSDAEQYLKSLYDLYTRTTGLSSKLMEFNLGTDKQTFLSKLIKSIF 342
           +C K   E+ LK + D+Y+    L+ +L   N+GT    F +K I ++ 
Sbjct: 52  QCHKHIKEEILKVMLDIYSTQNALNIQLRNDNIGTGSV*F*TKNISNVM 198
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|58037543|ref|NP_941991.1| latrophilin 3 [Mus
musculus]
         (1543 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

25479                                                                 132   1e-30
15664                                                                  51   5e-07
32189                                                                  49   1e-05
18071                                                                  46   9e-05
17433                                                                  30   9.9  
>25479
          Length = 507

 Score =  132 bits (331), Expect = 1e-30,   Method: Composition-based stats.
 Identities = 63/169 (37%), Positives = 91/169 (53%)
 Frame = +1

Query: 1035 IMLVEVFESEHSRRKYFYLVGYGMPALIVAVSAAVDYRSYGTDKVCWLRLDTYFIWSFIG 1094
            +MLV+VF++  SR  Y+Y   YG P L++AVSA   YR YGTD+ CWL  + YFIWSFIG
Sbjct: 1    LMLVQVFDASRSRLPYYYAAAYGPPVLVIAVSAGFYYRGYGTDRYCWLTTEKYFIWSFIG 180

Query: 1095 PATLIIMLNVIFLGIALYKMFHHTAILKPESGCLDNINYEDNRPFIKSWVIXXXXXXXXX 1154
            P   I+  N + L  A+  +F H+  +            +     I+SW+          
Sbjct: 181  PVAAILFANTVILIYAMIMVFRHSEYVF-------GAKEKSTASGIRSWIQGCFALEVLL 339

Query: 1155 XXXXXXXXMYINESTVIMAYLFTIFNSLQGMFIFIFHCVLQKKVRKEYG 1203
                     ++ E TV +AY+FT  N+LQG+FIF+FHCV  ++  +  G
Sbjct: 340  GIHVGGGFFFLGEQTVAVAYVFTALNTLQGLFIFLFHCVFNRRHVRSTG 486
>15664
          Length = 622

 Score = 50.8 bits (120), Expect(2) = 5e-07,   Method: Composition-based stats.
 Identities = 35/148 (23%), Positives = 64/148 (43%), Gaps = 1/148 (0%)
 Frame = -3

Query: 1053 LVGYGMPALIVAVSAAVDYRSY-GTDKVCWLRLDTYFIWSFIGPATLIIMLNVIFLGIAL 1111
            ++ +G+P + V V  A+D   Y G D  CW++L  ++ ++F  P  +++++N +     +
Sbjct: 503  IISWGLPTIPVIVMCALDTDLYRGYDFCCWMKLSAFY-YAFFLPVCIVLVVNTV-----I 342

Query: 1112 YKMFHHTAILKPESGCLDNINYEDNRPFIKSWVIXXXXXXXXXXXXXXXXXMYINESTVI 1171
            Y M   T   +P+ G       + N+P +   +                      E+ V+
Sbjct: 341  YIMVVVTLCRRPDMG-------QQNKPMLT--IRASFASFVFLGLSWMFSFFTFKETGVV 189

Query: 1172 MAYLFTIFNSLQGMFIFIFHCVLQKKVR 1199
              Y+FT   +LQG  IFI        VR
Sbjct: 188  FEYIFTTCTTLQGFLIFILFTARDXAVR 105

 Score = 22.7 bits (47), Expect(2) = 5e-07,   Method: Compositional matrix adjust.
 Identities = 9/17 (52%), Positives = 13/17 (76%)
 Frame = -1

Query: 1024 TWMFLEGVQLYIMLVEV 1040
             WM +EGV  Y++LV+V
Sbjct: 592  MWMLVEGVLQYLLLVKV 542
>32189
          Length = 1688

 Score = 49.3 bits (116), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 34/124 (27%), Positives = 57/124 (45%), Gaps = 6/124 (4%)
 Frame = -1

Query: 1091 SFIGPATLIIMLN-VIFLGIA---LYKMFHHTAILKPESGCLDNINYEDNRPFI--KSWV 1144
            S + PA +++++N VIF+ +A   L   F H    + E      +       F+   +WV
Sbjct: 1622 SLVAPACVVLVINTVIFVLVARVILKPRFQHQKQKEAEGVTPAQVRGAFTVMFLLGVTWV 1443

Query: 1145 IXXXXXXXXXXXXXXXXXMYINESTVIMAYLFTIFNSLQGMFIFIFHCVLQKKVRKEYGK 1204
                              + INE+ V+  YLF I NSLQG  +F+F C+   +VR  + +
Sbjct: 1442 FGP---------------LAINEAKVVFNYLFCILNSLQGFLVFVFRCLFNPEVRMCWVQ 1308

Query: 1205 CLRT 1208
             ++T
Sbjct: 1307 LVKT 1296
>18071
          Length = 473

 Score = 46.2 bits (108), Expect = 9e-05,   Method: Composition-based stats.
 Identities = 27/117 (23%), Positives = 51/117 (43%)
 Frame = -3

Query: 991  AELLFLIGINRTDQPIACXXXXXXXXXXXXXXXTWMFLEGVQLYIMLVEVFESEHSRRKY 1050
            ++L+  + + R++ P  C                WMF EG+ L+ ++V  F  E+     
Sbjct: 408  SQLMTRLDVTRSN-PTWCKVIHVLTQYISLSNYFWMFCEGLFLHTIIVHAFSKENKLLWA 232

Query: 1051 FYLVGYGMPALIVAVSAAVDYRSYGTDKVCWLRLDTYFIWSFIGPATLIIMLNVIFL 1107
             Y +G+G+P +      AV   +   D+ CW+    + +W    P    +++N IF 
Sbjct: 231  CYTIGWGVPVIPTVAYVAVRATNQELDRDCWIP-SGWPLWIINAPIAASLVVNFIFF 64
>17433
          Length = 459

 Score = 29.6 bits (65), Expect = 9.9,   Method: Compositional matrix adjust.
 Identities = 12/32 (37%), Positives = 20/32 (62%)
 Frame = +3

Query: 400 NEATGNKIDYIYNTDQSKDSLVDVPFPNSYQY 431
           +E   N ++Y + +  + ++L DVP P SYQY
Sbjct: 201 DEQKANTLNYFFQSVFTTETLNDVPVPPSYQY 296
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6679479|ref|NP_032961.1| prominin 1 [Mus musculus]
         (858 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

06705                                                                 110   1e-30
31322                                                                  36   0.084
>06705
          Length = 1176

 Score =  110 bits (275), Expect(2) = 1e-30,   Method: Compositional matrix adjust.
 Identities = 74/289 (25%), Positives = 147/289 (50%), Gaps = 3/289 (1%)
 Frame = +1

Query: 538 LFNNPDINMTFEQVYRDCKRGRGIYAAFQLENVVNVSDHFNIDQISENINTELENLNVNI 597
           LFN  ++ +    +   C++ R IY   QL+N+VN++ + ++  +   +++ L++ + NI
Sbjct: 226 LFNGKNVRLDLVDILDGCEKNRPIYNIMQLQNMVNLTQYTDLAPLKTELDS-LKSASFNI 402

Query: 598 DSIELLDNTGRKSLEDFAHSGIDTIDYSTYLKETEKSPTEVNLLTFASTLEAKANQLPEG 657
             I ++ +   +++ DFA SG+D++++  Y  E  K+ T  +L T A+ L     Q    
Sbjct: 403 PDITIVTSQLNQTVTDFATSGLDSVNFPEYYSEINKNLTAGDLHTLATNLRNIGYQSSAS 582

Query: 658 KLKQAFLLD-VQNIRAIHQHLLPPVQQSLNTLRQSVWTLQ-QTSNKLPEKVKKILASLDS 715
           +  ++ +L     +  + + L+ P++Q++ +L  S+  LQ Q  +++      +L+ L +
Sbjct: 583 EQFRSIMLGKADQLDNLDRTLVFPMKQAVKSLNASLKFLQTQGEDEIKPATAALLSGLQT 762

Query: 716 VQ-HFLTNNVSLIVIGETKKFGKTILGYFEHYLHWVFYAITEKMTSCKPMATAMDSAVNG 774
            Q +F T    L+        G+ +L     ++  +   + E +  C+P+     SA + 
Sbjct: 763 AQDNFNTKKTELVRTQLDVVIGR-VLQVANGFIDEMLTDVDENIGLCRPVYDGFYSASDA 939

Query: 775 ILCGYVADPLNLFWFGIGKATVLLLPAVIIAIKLAKYYRRMDSEDVYDD 823
           + C  V +PLN FWF +G      +P +I A+KLA  YRR   E  +DD
Sbjct: 940 V-CVVVLEPLNGFWFSLGWCLFFCIPCLIFAVKLAGLYRREHDEKDFDD 1083

 Score = 41.6 bits (96), Expect(2) = 1e-30,   Method: Composition-based stats.
 Identities = 16/32 (50%), Positives = 22/32 (68%)
 Frame = +2

Query: 466 CVSNTGGIFLMAGVGFGFLFCWILMILVVLTF 497
           C + TG  FLMAGV F F+  W++M++ VL F
Sbjct: 17  CNTGTGANFLMAGVAFTFMLAWLVMVVCVLLF 112
>31322
          Length = 536

 Score = 35.8 bits (81), Expect = 0.084,   Method: Composition-based stats.
 Identities = 32/115 (27%), Positives = 51/115 (44%), Gaps = 5/115 (4%)
 Frame = +2

Query: 490 MILVVLTFVVGANVEKLLCEPYENKKLLQ-VLDTPYLLKEQWQFYLSGMLFNNPDIN-MT 547
           M L    F  GAN+EK +C+P  +  + + V+D P  +      YLS +L  N  +  + 
Sbjct: 101 MALSAAGFYAGANLEKAVCQPARHFGIAENVVDYPDGMPGHAGIYLSDVLLGNGSLAPLY 280

Query: 548 FEQVYRDCKRGRGIYAAFQLENVV--NVSDHF-NIDQISENINTELENLNVNIDS 599
            + V   C  G   Y  F L +VV  N+ D   N  +   N+    + + V + S
Sbjct: 281 LKDVLTSCGNGSTAYTVF-LHHVVVPNLQDDLQNFTRHFSNLTGLFDRMRVGLPS 442
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31982561|ref|NP_703187.2| reticulon 1 isoform RTN1-A
[Mus musculus]
         (780 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

19825                                                                 130   2e-30
12552                                                                  29   8.2  
>19825
          Length = 642

 Score =  130 bits (328), Expect = 2e-30,   Method: Compositional matrix adjust.
 Identities = 54/129 (41%), Positives = 85/129 (65%)
 Frame = +3

Query: 592 KAIDLLYWRDIKQTGIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTISFRIYKSVLQA 651
           + +DL+YWRD+++TG+                               T+SFR+YK+++ A
Sbjct: 255 RVLDLIYWRDVRKTGVVFGCMMLVLLSLACFSLMSVLAYLSLAVLTVTLSFRLYKNIMAA 434

Query: 652 VQKTDEGHPFKAYLELEITLSQEQIQKYTDCLQLYVNSTLKELRRLFLVQDLVDSLKFAV 711
           VQK+++GHPFK YL+L+ITL +E++ + T  +  +VN +L ELRRLFL++DLVDS+KF +
Sbjct: 435 VQKSNDGHPFKQYLDLDITLKEERVSRVTQTVLQHVNRSLLELRRLFLIEDLVDSIKFGL 614

Query: 712 LMWLLTYVG 720
           L+W+LTY+G
Sbjct: 615 LLWVLTYIG 641
>12552
          Length = 1266

 Score = 28.9 bits (63), Expect = 8.2,   Method: Compositional matrix adjust.
 Identities = 18/45 (40%), Positives = 21/45 (46%), Gaps = 2/45 (4%)
 Frame = +1

Query: 489  PMKPGALDAIREETGSRATEERAPSHQGPVEP--DPMLSFAPAAA 531
            P  PG LD   + TG  ATE   P   GP  P   P  S +P A+
Sbjct: 1033 PATPGCLDWCHQHTGLVATESCCPYS*GPGLPGSSPGFSRSPPAS 1167
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|33859650|ref|NP_035973.1| membrane bound C2 domain
containing protein [Mus musculus]
         (1092 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

36305                                                                  79   2e-30
31935                                                                  76   6e-14
16549                                                                  67   3e-11
29179                                                                  59   1e-08
13896                                                                  40   0.004
30040                                                                  38   0.028
18322                                                                  38   0.029
26525                                                                  36   0.077
05343                                                                  30   4.3  
>36305
          Length = 586

 Score = 79.0 bits (193), Expect(2) = 2e-30,   Method: Compositional matrix adjust.
 Identities = 49/120 (40%), Positives = 67/120 (55%), Gaps = 2/120 (1%)
 Frame = -3

Query: 417 GVLDNWYPLQG-GQGQVHLRLEWLSLLPDAEKLDQVLQWNRGITSRPEPPSAAILVVYLD 475
           G +D W PL+   +G VH+   WL L  D  +LD+V++  R      +   AA+LVV LD
Sbjct: 362 GNVDEWLPLEDVKKGMVHVSATWLYLANDPLELDRVMEQVRDEGVDEDSVHAALLVVNLD 183

Query: 476 RAQDLPL-KKGNKEPNPMVQLSVQDVTRESKATYSTNSPVWEEAFRFFLQDPRSQELDVQ 534
            A DLP  KK   EP+P V L +    +ES    +T  P WEE FRFF+ +P  Q LD++
Sbjct: 182 SALDLPRDKKSLLEPSPYVTLRLGQTEQESGIRNATTEPRWEENFRFFVANPNHQSLDLE 3

 Score = 72.8 bits (177), Expect(2) = 2e-30,   Method: Composition-based stats.
 Identities = 32/77 (41%), Positives = 51/77 (66%), Gaps = 1/77 (1%)
 Frame = -1

Query: 343 EGKSDPYALVRVGTQTFCSRVIDEELNPHWGETYEVIVHEVPGQEIEVEVFDKDP-DKDD 401
           +GKSDPY +V VG QTF ++VID+ + P W E +E ++ E  GQ +++ + DKDP +KDD
Sbjct: 586 KGKSDPYTVVTVGAQTFKTKVIDDTVEPRWNEVFEFVIDERDGQILKLNISDKDPGNKDD 407

Query: 402 FLGRMKLDVGKVLQAGV 418
            LG   +D+  + +  +
Sbjct: 406 PLGSTTMDISTIFEKAM 356

 Score = 67.0 bits (162), Expect(2) = 4e-21,   Method: Compositional matrix adjust.
 Identities = 44/122 (36%), Positives = 67/122 (54%), Gaps = 2/122 (1%)
 Frame = -3

Query: 732 GFLDEWLTLEDVPSGRLHLRLERLTPRPTAAELEEVL-QVNSLIQTQKSSELAAALLSVF 790
           G +DEWL LEDV  G +H+    L       EL+ V+ QV    +      + AALL V 
Sbjct: 362 GNVDEWLPLEDVKKGMVHVSATWLYLANDPLELDRVMEQVRD--EGVDEDSVHAALLVVN 189

Query: 791 LERAEDLPL-RKGTKPPSPYATITVGETSHKTKTVSQSSAPVWEESASFLIRKPHAESLE 849
           L+ A DLP  +K    PSPY T+ +G+T  ++   + ++ P WEE+  F +  P+ +SL+
Sbjct: 188 LDSALDLPRDKKSLLEPSPYVTLRLGQTEQESGIRNATTEPRWEENFRFFVANPNHQSLD 9

Query: 850 LQ 851
           L+
Sbjct: 8   LE 3

 Score = 53.5 bits (127), Expect(2) = 4e-21,   Method: Composition-based stats.
 Identities = 22/50 (44%), Positives = 34/50 (68%)
 Frame = -1

Query: 658 KGKSDPYVKLKVAGKSFRTHVVREDLNPRWNEVFEVIVTSIPGQELEIEV 707
           KGKSDPY  + V  ++F+T V+ + + PRWNEVFE ++    GQ L++ +
Sbjct: 586 KGKSDPYTVVTVGAQTFKTKVIDDTVEPRWNEVFEFVIDERDGQILKLNI 437

 Score = 40.0 bits (92), Expect = 0.005,   Method: Composition-based stats.
 Identities = 20/70 (28%), Positives = 36/70 (51%), Gaps = 4/70 (5%)
 Frame = -1

Query: 808 PYATITVGETSHKTKTVSQSSAPVWEESASFLIRKPHAESLELQVRGEGTGT----LGSV 863
           PY  +TVG  + KTK +  +  P W E   F+I +   + L+L +  +  G     LGS 
Sbjct: 571 PYTVVTVGAQTFKTKVIDDTVEPRWNEVFEFVIDERDGQILKLNISDKDPGNKDDPLGST 392

Query: 864 SLPLSELLQE 873
           ++ +S + ++
Sbjct: 391 TMDISTIFEK 362
>31935
          Length = 554

 Score = 76.3 bits (186), Expect = 6e-14,   Method: Compositional matrix adjust.
 Identities = 42/127 (33%), Positives = 71/127 (55%), Gaps = 3/127 (2%)
 Frame = -3

Query: 960  LGQVKLTVWYHSDEQKLISIIHSCRAL-RQNGRDLPDPYVSVLLLPDKNRSTKRKTPQKK 1018
            LG+++LT+ Y +  QKL   IH    +  ++   +PDPYV + LLP +++ +KRKT   K
Sbjct: 540  LGRIQLTITYSAQRQKLDVTIHKIMNIPLRDPSSIPDPYVKLHLLPGRSKESKRKTSIIK 361

Query: 1019 RTLNPEFNERFEWDLPLDGTLRRKLDVSVKSNSSFMSRERELLG--KVQLDLAEIDLSQG 1076
               NP ++  FE+ + +      +L+V+V +   F+S    ++G  K+ LD +EI    G
Sbjct: 360  DNCNPVYDASFEYLISISELRHTELEVTVCTQKGFLSSGSPIIGMLKIPLDDSEITTPAG 181

Query: 1077 AAQWYDL 1083
               W+DL
Sbjct: 180  LKSWFDL 160

 Score = 37.0 bits (84), Expect = 0.043,   Method: Compositional matrix adjust.
 Identities = 27/111 (24%), Positives = 46/111 (41%), Gaps = 13/111 (11%)
 Frame = -3

Query: 787 LSVFLERAEDLPLRKGTKPPSPYATITV-----GETSHKTKTVSQSSAPVWEESASFLIR 841
           L V + +  ++PLR  +  P PY  + +      E+  KT  +  +  PV++ S  +LI 
Sbjct: 492 LDVTIHKIMNIPLRDPSSIPDPYVKLHLLPGRSKESKRKTSIIKDNCNPVYDASFEYLIS 313

Query: 842 KPHAESLELQVR--------GEGTGTLGSVSLPLSELLQEDQLCLDHWFAL 884
                  EL+V           G+  +G + +PL +        L  WF L
Sbjct: 312 ISELRHTELEVTVCTQKGFLSSGSPIIGMLKIPLDDSEITTPAGLKSWFDL 160
>16549
          Length = 607

 Score = 67.4 bits (163), Expect = 3e-11,   Method: Compositional matrix adjust.
 Identities = 41/107 (38%), Positives = 60/107 (56%)
 Frame = +2

Query: 977  ISIIHSCRALRQNGRDLPDPYVSVLLLPDKNRSTKRKTPQKKRTLNPEFNERFEWDLPLD 1036
            I ++H  R L ++  +LP PYV   LLPD  + TKRKT   K +++P FNE  ++ +   
Sbjct: 14   IMVMH-VRDLARSA-ELPSPYVKTYLLPDPEKQTKRKTKIVKHSVHPTFNEVLQYRMKET 187

Query: 1037 GTLRRKLDVSVKSNSSFMSRERELLGKVQLDLAEIDLSQGAAQWYDL 1083
             T  R L V+V  +   M +E   LG V L L +++LS   A+WY L
Sbjct: 188  ETRHRTLQVTVWDHD--MLKENNFLGAVYLRLRDLELSDDTAKWYTL 322
>29179
          Length = 1113

 Score = 58.9 bits (141), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 50/137 (36%), Positives = 70/137 (51%), Gaps = 4/137 (2%)
 Frame = -3

Query: 960  LGQVKLTVWYHSDEQKLISIIHSCRALRQNGRDL---PDPYVSVLLLPDKNRSTKRKTPQ 1016
            LG+++  + Y  D Q L   +   RA+    +D+    DPYV +LLLPDK    K  T  
Sbjct: 541  LGRIQFGLMY--DFQNLTLTLRIIRAVDLPAKDVTGTSDPYVKILLLPDKKH--KLLTKV 374

Query: 1017 KKRTLNPEFNERFEWD-LPLDGTLRRKLDVSVKSNSSFMSRERELLGKVQLDLAEIDLSQ 1075
            KKR LNP +NE F ++  P +  L + L + V     F SR+ + +G+  L L EIDLSQ
Sbjct: 373  KKRNLNPHWNECFLFEGWPHNKLLEKTLYLQVIDYDRF-SRD-DPIGETYLPLNEIDLSQ 200

Query: 1076 GAAQWYDLMDDRDKGGS 1092
                W  L   +D  G 
Sbjct: 199  SPVSWKYLQPCKDTRGK 149

 Score = 40.8 bits (94), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 24/60 (40%), Positives = 31/60 (51%), Gaps = 3/60 (5%)
 Frame = -3

Query: 635 VLRIHVLEAQDLIAKDRFLGGLVKGKSDPYVKLKV---AGKSFRTHVVREDLNPRWNEVF 691
            L + ++ A DL AKD      V G SDPYVK+ +         T V + +LNP WNE F
Sbjct: 496 TLTLRIIRAVDLPAKD------VTGTSDPYVKILLLPDKKHKLLTKVKKRNLNPHWNECF 335

 Score = 30.8 bits (68), Expect = 3.5,   Method: Compositional matrix adjust.
 Identities = 32/96 (33%), Positives = 44/96 (45%), Gaps = 12/96 (12%)
 Frame = -3

Query: 787 LSVFLERAEDLPLRKGTKPPSPYATI-TVGETSHK--TKTVSQSSAPVWEESASFLIRK- 842
           L++ + RA DLP +  T    PY  I  + +  HK  TK   ++  P W E   FL    
Sbjct: 493 LTLRIIRAVDLPAKDVTGTSDPYVKILLLPDKKHKLLTKVKKRNLNPHWNE--CFLFEGW 320

Query: 843 PHAESLE----LQV----RGEGTGTLGSVSLPLSEL 870
           PH + LE    LQV    R      +G   LPL+E+
Sbjct: 319 PHNKLLEKTLYLQVIDYDRFSRDDPIGETYLPLNEI 212

 Score = 29.6 bits (65), Expect = 6.3,   Method: Compositional matrix adjust.
 Identities = 16/59 (27%), Positives = 27/59 (45%), Gaps = 3/59 (5%)
 Frame = -3

Query: 321 IRIHLLAARGLSSKDKYVKGLIEGKSDPYALVRV---GTQTFCSRVIDEELNPHWGETY 376
           + + ++ A  L +KD      + G SDPY  + +         ++V    LNPHW E +
Sbjct: 493 LTLRIIRAVDLPAKD------VTGTSDPYVKILLLPDKKHKLLTKVKKRNLNPHWNECF 335
>13896
          Length = 827

 Score = 40.4 bits (93), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 27/84 (32%), Positives = 40/84 (47%)
 Frame = +2

Query: 325 LLAARGLSSKDKYVKGLIEGKSDPYALVRVGTQTFCSRVIDEELNPHWGETYEVIVHEVP 384
           +L AR L SK K       G +D Y  +++G + + +  I    NP W E  ++ +  + 
Sbjct: 170 VLRARNLISKGK------SGNNDVYVTIQLGKEKYQTSTIRNAHNPEWFEECDLPIPHLH 331

Query: 385 GQEIEVEVFDKDPDKDDFLGRMKL 408
             EIEV V+      DDFLG   L
Sbjct: 332 S-EIEVSVYHXGVLSDDFLGYTSL 400

 Score = 37.4 bits (85), Expect = 0.033,   Method: Compositional matrix adjust.
 Identities = 23/68 (33%), Positives = 35/68 (51%)
 Frame = +2

Query: 640 VLEAQDLIAKDRFLGGLVKGKSDPYVKLKVAGKSFRTHVVREDLNPRWNEVFEVIVTSIP 699
           VL A++LI+K +       G +D YV +++  + ++T  +R   NP W   FE     IP
Sbjct: 170 VLRARNLISKGK------SGNNDVYVTIQLGKEKYQTSTIRNAHNPEW---FEECDLPIP 322

Query: 700 GQELEIEV 707
               EIEV
Sbjct: 323 HLHSEIEV 346

 Score = 35.8 bits (81), Expect = 0.089,   Method: Compositional matrix adjust.
 Identities = 29/98 (29%), Positives = 44/98 (44%), Gaps = 3/98 (3%)
 Frame = +2

Query: 793 RAEDLPLRKGTKPPSPYATITVGETSHKTKTVSQSSAPVWEESASFLIRKPHAESLELQV 852
           RA +L  +  +     Y TI +G+  ++T T+  +  P W E     I   H+E +E+ V
Sbjct: 176 RARNLISKGKSGNNDVYVTIQLGKEKYQTSTIRNAHNPEWFEECDLPIPHLHSE-IEVSV 352

Query: 853 RGEGTGT---LGSVSLPLSELLQEDQLCLDHWFALSGQ 887
              G  +   LG  SLPL E   ED      W +L  +
Sbjct: 353 YHXGVLSDDFLGYTSLPLWEQRLEDT-TKTQWISLKNK 463
>30040
          Length = 652

 Score = 37.7 bits (86), Expect = 0.028,   Method: Compositional matrix adjust.
 Identities = 17/53 (32%), Positives = 33/53 (62%)
 Frame = -3

Query: 995  DPYVSVLLLPDKNRSTKRKTPQKKRTLNPEFNERFEWDLPLDGTLRRKLDVSV 1047
            DP+V V LL +  +  ++KT  ++ ++NP +NE   +++P +   +  L+VSV
Sbjct: 551  DPFVRVSLLVEGKKVKRKKTSVRRASINPVWNEALAFNVPAEVLPKVTLEVSV 393

 Score = 31.2 bits (69), Expect = 2.3,   Method: Compositional matrix adjust.
 Identities = 21/54 (38%), Positives = 28/54 (51%), Gaps = 7/54 (12%)
 Frame = -3

Query: 661 SDPYVK--LKVAGKSFR---THVVREDLNPRWNE--VFEVIVTSIPGQELEIEV 707
           +DP+V+  L V GK  +   T V R  +NP WNE   F V    +P   LE+ V
Sbjct: 554 ADPFVRVSLLVEGKKVKRKKTSVRRASINPVWNEALAFNVPAEVLPKVTLEVSV 393
>18322
          Length = 501

 Score = 37.7 bits (86), Expect = 0.029,   Method: Composition-based stats.
 Identities = 23/79 (29%), Positives = 42/79 (53%), Gaps = 3/79 (3%)
 Frame = -1

Query: 365 DEELNPHWGETYEVIVHEVPGQEIEVEVFDKDPDKDDFLGRMKLDVGKVLQAGV--LDNW 422
           +E L P W E   V + +  G  + ++VFDKD    DF+G++ L   K+ +  +     W
Sbjct: 390 EETLFPKWNELVTVEMKD-DGSTLTIDVFDKDMISKDFMGKVTLTAEKLKELSIKGAAEW 214

Query: 423 YPLQGGQ-GQVHLRLEWLS 440
           +PL+  + G++ L+   +S
Sbjct: 213 FPLERTKSGKLQLKCHVIS 157
>26525
          Length = 455

 Score = 36.2 bits (82), Expect = 0.077,   Method: Composition-based stats.
 Identities = 21/50 (42%), Positives = 30/50 (60%), Gaps = 3/50 (6%)
 Frame = +1

Query: 645 DLIAKDRFLGGLVKGKSDPYVKLKVAGKS---FRTHVVREDLNPRWNEVF 691
           DL  +D  LGG      DPYVKL++  +     +T VVR+ LNP+++E F
Sbjct: 1   DLPPRDPSLGG-----CDPYVKLQLLPEKKHKCKTRVVRKTLNPKYDETF 135

 Score = 35.4 bits (80), Expect = 0.13,   Method: Composition-based stats.
 Identities = 17/37 (45%), Positives = 25/37 (67%)
 Frame = +1

Query: 995  DPYVSVLLLPDKNRSTKRKTPQKKRTLNPEFNERFEW 1031
            DPYV + LLP+K    K KT   ++TLNP+++E F +
Sbjct: 37   DPYVKLQLLPEKKH--KCKTRVVRKTLNPKYDETFTF 141
>05343
          Length = 759

 Score = 30.4 bits (67), Expect = 4.3,   Method: Composition-based stats.
 Identities = 12/21 (57%), Positives = 15/21 (71%)
 Frame = -1

Query: 439 LSLLPDAEKLDQVLQWNRGIT 459
           L  LPD E LD+V+ WNR +T
Sbjct: 654 LDFLPDCETLDKVVCWNRPLT 592
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|84370256|ref|NP_598530.2| cytoplasmic FMR1
interacting protein 2 [Mus musculus]
         (1253 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

12370                                                                 131   2e-30
03267                                                                  31   4.1  
12267                                                                  30   4.6  
03272                                                                  30   6.5  
>12370
          Length = 731

 Score =  131 bits (330), Expect = 2e-30,   Method: Composition-based stats.
 Identities = 55/92 (59%), Positives = 75/92 (81%)
 Frame = -1

Query: 1161 CSIIVLLGQQRRFDLFDFCYHLLKVQRQDGKDEIIKNVPLKKMADRIRKYQILNNEVFAI 1220
            C +IVLLGQQRRF+  DFCYH+L+VQR DGKDE +K + LK+M DRIR++Q+LN+++F+I
Sbjct: 731  CVMIVLLGQQRRFEALDFCYHILRVQRVDGKDEDVKGIQLKRMVDRIRRFQVLNSQIFSI 552

Query: 1221 LNKYMKSVETDSSTVEHVRCFQPPIHQSLATT 1252
            LNKY+K  + + S VEHVRCF PP H S+ ++
Sbjct: 551  LNKYLKGGDGEGSNVEHVRCFPPPQHPSVISS 456
>03267
          Length = 2120

 Score = 30.8 bits (68), Expect = 4.1,   Method: Composition-based stats.
 Identities = 16/60 (26%), Positives = 30/60 (50%), Gaps = 5/60 (8%)
 Frame = -1

Query: 849 DFLPNYCYNGSTNRFVRTAIPFTQEPQRDKPANVQPYY-----LYGSKPLNIAYSHIYSS 903
           DFLPN C+    N+F +       +PQR+   N+  ++        S+   + Y+H++S+
Sbjct: 641 DFLPNRCHTSKQNKFAKEK---QNKPQRNANKNLGFFF*LALASCSSRYFYLYYTHLFST 471
>12267
          Length = 820

 Score = 30.4 bits (67), Expect = 4.6,   Method: Composition-based stats.
 Identities = 13/32 (40%), Positives = 21/32 (65%), Gaps = 2/32 (6%)
 Frame = -2

Query: 806 LTHRLLCKHMTLDSFDAMFREANHNVSA--PY 835
           +T R++C H+T++SF  + R  + NVS   PY
Sbjct: 111 VTLRVICSHLTINSFQGLSRHQDSNVSENFPY 16
>03272
          Length = 3104

 Score = 30.0 bits (66), Expect = 6.5,   Method: Compositional matrix adjust.
 Identities = 19/52 (36%), Positives = 26/52 (50%)
 Frame = -2

Query: 141  KRLCHAERRKDFVSEAYLLTLGKFINMFAVLDELKNMKCSVKNDHSAYKRAA 192
            KRL  + RR++FV E  L    K I   +VL    +M C++K  H   K  A
Sbjct: 1246 KRLNTSTRRRNFVIEEML*LKDKCIAFISVLSSCLHMVCNLKKGHFCLKTFA 1091
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|122937361|ref|NP_032162.2| guanine nucleotide binding
protein, related sequence 1 [Mus musculus]
         (607 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

20319                                                                 129   3e-30
00817                                                                  84   1e-16
15021                                                                  79   6e-15
14433                                                                  65   1e-10
27367                                                                  53   4e-07
28329                                                                  44   2e-04
09246                                                                  41   0.001
18173                                                                  36   0.057
22318                                                                  35   0.079
17271                                                                  33   0.29 
35806                                                                  33   0.49 
29946                                                                  30   2.9  
>20319
          Length = 1200

 Score =  129 bits (325), Expect = 3e-30,   Method: Compositional matrix adjust.
 Identities = 95/300 (31%), Positives = 134/300 (44%), Gaps = 7/300 (2%)
 Frame = +1

Query: 247 PQLHIVLFTSFPRDTRTPQEPGGVLKKNRRRGKGWTRALGPEQLLRACEAITVGKVDLSS 306
           P+  IV F+S P+   +P +     +   RR K   + +GP+ LL  C  +   KV L S
Sbjct: 109 PRARIVCFSSVPK---SPDDAASGFRS--RRQKKRMKPMGPQHLLDVCNELVKDKVSLES 273

Query: 307 WREKIARDVAGASWGNVSGXXXXXXDGPAVLVEQLTDSAMEPTGPSRERYKDGVVTIGCI 366
           W+EK+  D    S            D    L      S  +      +RY+DG++TIGCI
Sbjct: 274 WQEKLNADDTATS---APDRHACHGDAAEDLSAHRAGSGEDHFAGIYQRYRDGILTIGCI 444

Query: 367 GFPNVGKSSLINGLVGRKVVSVSRTPGHTRYFQTYFLTPSVKLCDCPGLIFPSLLPRQLQ 426
           G+PNVGKSSL+NGLVGRKVVSVS+        + Y   P       P   FP       +
Sbjct: 445 GYPNVGKSSLLNGLVGRKVVSVSKHRVTPNTCRXYS*RPLYVCVTAPVSSFPPTSTNLFR 624

Query: 427 VLAGIYPIAQIQEPYTSVGYLASRIPVQALLHLRHPEA-----EDPSAEHPWCAWDICEA 481
              G  P  + + P        S    ++      P +       P A+  WC   +   
Sbjct: 625 FCRGFSPSLR*ESPTRQ*RTWLSTWICRSFFA*LXPTS*PGPPLAPHAQRRWCGPLLTSV 804

Query: 482 WAEKRGYKTAKAARN--DVYRAANSLLRLAVDGRLSLCFYPPGYSEQRGTWESHPETAEL 539
              +    T+       DVYRAAN +LRLAVDG+L LC  PP + +++  W++ P T  L
Sbjct: 805 KVGR*SAVTSXPRHXGPDVYRAANQILRLAVDGKLCLCLAPPTFFDRQDIWQTDPFTITL 984
>00817
          Length = 2606

 Score = 84.3 bits (207), Expect = 1e-16,   Method: Compositional matrix adjust.
 Identities = 56/160 (35%), Positives = 80/160 (50%), Gaps = 1/160 (0%)
 Frame = +3

Query: 361 VTIGCIGFPNVGKSSLINGLVGRKVVSVSRTPGHTRYFQTYFLTPSVKLCDCPGLIFPSL 420
           +++G IG+PNVGKSS+IN L  +KV  V+   G T+ +Q   L   + L DCPG+++P+ 
Sbjct: 609 ISVGLIGYPNVGKSSIINALKAKKVCKVAPLAGETKVWQYVTLMKRIYLVDCPGIVYPTG 788

Query: 421 LPRQLQVLAGIYPIAQIQEPYTSVGYLASRIPVQALLHLRHPEAEDPSAEHPW-CAWDIC 479
             R   VL G+  I  +++P   VG +  R+    L      +A D +    W  A D  
Sbjct: 789 ATRTDSVLKGVVRIENVRDPQDYVGAMLERVKSDYL-----KKAYDITQ---WENADDFL 944

Query: 480 EAWAEKRGYKTAKAARNDVYRAANSLLRLAVDGRLSLCFY 519
           E  A + G K  K    DV  AA  LL     GR  L F+
Sbjct: 945 EQVARRLG-KLLKGGEPDVSTAAKMLLNRXRGGRHVLFFF 1061

 Score = 38.9 bits (89), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 16/49 (32%), Positives = 27/49 (55%)
 Frame = +3

Query: 403 LTPSVKLCDCPGLIFPSLLPRQLQVLAGIYPIAQIQEPYTSVGYLASRI 451
           L   + L DCPG+++P+   R   VL G+  I  +++P   VG +  R+
Sbjct: 6   LMKRIYLVDCPGIVYPTGATRTDSVLKGVVRIENVRDPQDYVGAMLERV 152

 Score = 37.0 bits (84), Expect = 0.021,   Method: Compositional matrix adjust.
 Identities = 19/55 (34%), Positives = 34/55 (61%), Gaps = 1/55 (1%)
 Frame = +3

Query: 178 WRQLWRVLEMSDIVLLITDIRHPVVNFPPALYEYVTGEL-GLALVLVLNKVDLAP 231
           W +L++V++ SD+++ + D R P+      + +Y+  E     ++LVLNKVDL P
Sbjct: 294 WNELYKVIDSSDVLIQVLDARDPLGTRCYQVEKYLKKEKPHKHVILVLNKVDLVP 458
>15021
          Length = 572

 Score = 78.6 bits (192), Expect = 6e-15,   Method: Compositional matrix adjust.
 Identities = 53/155 (34%), Positives = 82/155 (52%), Gaps = 7/155 (4%)
 Frame = -1

Query: 395 TRYFQTYFLTPSVKLCDCPGLIFPSLLPRQLQ-VLAGIYPIAQIQE---PYTSVGYLASR 450
           T++FQT ++   + LCDCPGL+FPS +  + + V+ GI PI Q+Q+   P   V +   R
Sbjct: 569 TKHFQTLYVEKDLMLCDCPGLVFPSFVNSKAELVVNGILPIDQLQDSEPPVELVCHRVGR 390

Query: 451 IPVQALLHLRHP---EAEDPSAEHPWCAWDICEAWAEKRGYKTAKAARNDVYRAANSLLR 507
              + L H+  P   E EDP  +    A+D+ +A+   RG+ + K    D  RAA  +L+
Sbjct: 389 RAFETLYHINLPPPEEWEDP--DKAPSAYDLLQAYGALRGFMSHK-GNPDRPRAARYILK 219

Query: 508 LAVDGRLSLCFYPPGYSEQRGTWESHPETAELVLS 542
             V+G+L  C  PPG   + G ++  P     V S
Sbjct: 218 DFVNGKLLFCHPPPGI--ETGAFQKPPYGKPQVFS 120
>14433
          Length = 520

 Score = 64.7 bits (156), Expect = 1e-10,   Method: Composition-based stats.
 Identities = 34/97 (35%), Positives = 51/97 (52%)
 Frame = +3

Query: 361 VTIGCIGFPNVGKSSLINGLVGRKVVSVSRTPGHTRYFQTYFLTPSVKLCDCPGLIFPSL 420
           + +G +GFPN GKSS+IN L   K  +V  TPG TR  Q   L   +KL D PG++  + 
Sbjct: 6   IRVGIVGFPNTGKSSIINSLKRSKACTVGATPGVTRAMQEVNLDKHIKLLDSPGVVMETS 185

Query: 421 LPRQLQVLAGIYPIAQIQEPYTSVGYLASRIPVQALL 457
                 VL  +  +  I++P   V ++ SR   + L+
Sbjct: 186 QSPVTAVLRNVVRLESIEDPVAPVQHILSRCSKEQLM 296
>27367
          Length = 478

 Score = 52.8 bits (125), Expect = 4e-07,   Method: Compositional matrix adjust.
 Identities = 40/153 (26%), Positives = 62/153 (40%), Gaps = 6/153 (3%)
 Frame = +2

Query: 1   MPRXXXXXXXXXXXQLQDKRERKRG----LQDGLXXXXXXXXXXXXXXXXQTDTSD--GE 54
           MPR           QLQ++RERK+       D L                  + SD  G+
Sbjct: 50  MPRKHAFSGKQKKKQLQERRERKKDSCGVYDDDLV----------------VEVSDDLGD 181

Query: 55  SVTHHIRRLNQQPSQGLGPRGYDPNRYRLHFERDSXXXXXXXXXXXXXQVLQPVSAEVLE 114
               H   +     Q +G + +DPN++RLHF + S              + + V  + LE
Sbjct: 182 DKGQHQPEVLHVHEQPMGDKDFDPNKFRLHFLKISAEEMKKRKRLAQQPITRVVEKD-LE 358

Query: 115 LDIREVYQPGSVLDFPRRPPWSYEMSKEQLMSQ 147
           + +  VY P   L FP+RPPW +  +   L ++
Sbjct: 359 VSVESVYVPEHSLHFPKRPPWDFRQTNNSLSNR 457
>28329
          Length = 373

 Score = 43.5 bits (101), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 27/49 (55%), Positives = 31/49 (63%), Gaps = 2/49 (4%)
 Frame = +3

Query: 350 GPSR--ERYKDGVVTIGCIGFPNVGKSSLINGLVGRKVVSVSRTPGHTR 396
           G SR  ER +DGV  +  IG PNVGKSSL+N L  R+   VS  PG TR
Sbjct: 186 GDSRRGERLRDGV-HLAIIGEPNVGKSSLLNTLCQRQAAIVSPLPGTTR 329
>09246
          Length = 1628

 Score = 41.2 bits (95), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 34/110 (30%), Positives = 49/110 (44%), Gaps = 1/110 (0%)
 Frame = +3

Query: 398 FQTYFLTPSVKLCDCPGLIFPSLLPRQLQVLAGIYPIAQIQEPYTSVGYLASRIPVQALL 457
           +Q   L   + L DCPG+++P+   R   VL G+  I  +++P   VG +  R+    L 
Sbjct: 3   WQYVTLMKRIYLXDCPGIVYPTGATRTDSVLKGVVRIENVRDPQDYVGAMLERVKSDYL- 179

Query: 458 HLRHPEAEDPSAEHPW-CAWDICEAWAEKRGYKTAKAARNDVYRAANSLL 506
                +A D +    W  A D  E  A + G K  K    DV  AA  LL
Sbjct: 180 ----KKAYDITQ---WENADDFLEQVARRLG-KLLKGGEPDVSTAAKMLL 305
>18173
          Length = 1308

 Score = 35.8 bits (81), Expect = 0.057,   Method: Compositional matrix adjust.
 Identities = 24/63 (38%), Positives = 30/63 (47%), Gaps = 8/63 (12%)
 Frame = +2

Query: 362 TIGCIGFPNVGKSSLINGLVGRKV-------VSVSRTPGHTRY-FQTYFLTPSVKLCDCP 413
           TI   GFPNVGKSS IN +    V        + S   GHT Y F  Y      ++ D P
Sbjct: 554 TIIICGFPNVGKSSFINKVTNADVEVQPYAFTTKSLYVGHTDYKFNRY------QVIDTP 715

Query: 414 GLI 416
           G++
Sbjct: 716 GIL 724
>22318
          Length = 808

 Score = 35.0 bits (79), Expect = 0.079,   Method: Compositional matrix adjust.
 Identities = 25/83 (30%), Positives = 39/83 (46%), Gaps = 13/83 (15%)
 Frame = +3

Query: 347 EPTGPSRER------YKDGVVTIGCIGFPNVGKSSLINGLV-------GRKVVSVSRTPG 393
           EPTG S  +       K G   +  IGFP+VGKS+L++ L          +  +++  PG
Sbjct: 180 EPTGKSSAKGEGFDVMKSGDARVALIGFPSVGKSTLLSTLTKTESECAAYEFTTLTCIPG 359

Query: 394 HTRYFQTYFLTPSVKLCDCPGLI 416
              Y        +++L D PG+I
Sbjct: 360 VIEY-----AGANIQLLDLPGII 413
>17271
          Length = 566

 Score = 33.5 bits (75), Expect = 0.29,   Method: Compositional matrix adjust.
 Identities = 19/58 (32%), Positives = 31/58 (53%), Gaps = 7/58 (12%)
 Frame = -2

Query: 366 IGFPNVGKSSLINGLVG-------RKVVSVSRTPGHTRYFQTYFLTPSVKLCDCPGLI 416
           +GFP+VGKS+L++ L G        +  +++  PG  RY         ++L D PG+I
Sbjct: 520 VGFPSVGKSTLLSNLAGVYSEVAAYEFTTLTTVPGVIRY-----KGAKIQLLDLPGII 362
>35806
          Length = 792

 Score = 32.7 bits (73), Expect = 0.49,   Method: Compositional matrix adjust.
 Identities = 20/50 (40%), Positives = 26/50 (52%)
 Frame = -2

Query: 121 YQPGSVLDFPRRPPWSYEMSKEQLMSQEERSFQEYLGKIHGAYTSEKLSY 170
           YQ   VLDFPR P  S  +   +L   EER F+  LG +     S+KL +
Sbjct: 404 YQTFVVLDFPRVPVVSVALPLLKLWQTEERVFRLALGDLDNG--SDKLLH 261
>29946
          Length = 1192

 Score = 30.0 bits (66), Expect = 2.9,   Method: Compositional matrix adjust.
 Identities = 27/73 (36%), Positives = 34/73 (46%)
 Frame = -1

Query: 103 QVLQPVSAEVLELDIREVYQPGSVLDFPRRPPWSYEMSKEQLMSQEERSFQEYLGKIHGA 162
           Q LQP +A VL+L +      G VL     PP  Y MSKE L    ER  Q  L +  G 
Sbjct: 976 QHLQP-AAPVLDLQLPGRVSEGEVL---VHPPHLYVMSKEMLGEIHERLLQVVLQQF-GG 812

Query: 163 YTSEKLSYFEHNL 175
             + +L +  H L
Sbjct: 811 LHAVRLLFIWHTL 773
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6755588|ref|NP_035558.1| synaptosomal-associated
protein 25 [Mus musculus]
         (206 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

08192                                                                 127   3e-30
21259                                                                 105   1e-23
07259                                                                  33   0.095
>08192
          Length = 768

 Score =  127 bits (319), Expect = 3e-30,   Method: Compositional matrix adjust.
 Identities = 67/131 (51%), Positives = 91/131 (69%), Gaps = 4/131 (3%)
 Frame = +2

Query: 77  NLTDLGKFCGLCVCPCNKLKSSDA---YKKAWGNNQDGVVASQ-PARVVDEREQMAISGG 132
           NL  L K CGLCV P  + K+ +    Y K W +N DG V +  P  VV +     +SGG
Sbjct: 92  NLEGLEKCCGLCVLPWKRSKNFEKGSDYNKTWKSNDDGKVNTNGPRVVVGDANGGMVSGG 271

Query: 133 FIRRVTNDARENEMDENLEQVSGIIGNLRHMALDMGNEIDTQNRQIDRIMEKADSNKTRI 192
           ++ R+ NDARE+EM++N+ +VSG+IGNLR+MA+DMGNEI++QNRQIDR+ +K  S   R+
Sbjct: 272 YVTRIMNDAREDEMEQNIGEVSGMIGNLRNMAVDMGNEIESQNRQIDRVNQKGVSLNDRV 451

Query: 193 DEANQRATKML 203
           D ANQRA K+L
Sbjct: 452 DVANQRAHKIL 484

 Score = 63.2 bits (152), Expect = 7e-11,   Method: Compositional matrix adjust.
 Identities = 31/51 (60%), Positives = 36/51 (70%)
 Frame = +3

Query: 47 LVMLDEQGEQLERIEEGMDQINKDMKEAEKNLTDLGKFCGLCVCPCNKLKS 97
          LVMLDEQGEQL+RIEEGMDQIN+DMK+AEK         G   CP N  ++
Sbjct: 3  LVMLDEQGEQLDRIEEGMDQINQDMKDAEKTSRVWRSVVGSVSCPGNGPRT 155
>21259
          Length = 425

 Score =  105 bits (262), Expect = 1e-23,   Method: Compositional matrix adjust.
 Identities = 53/74 (71%), Positives = 65/74 (87%)
 Frame = -1

Query: 4   DADMRNELEEMQRRADQLADESLESTRRMLQLVEESKDAGIRTLVMLDEQGEQLERIEEG 63
           D DMR EL+++Q +A+ + DESLESTRRML L EES+D GI+T+VMLDEQGEQL+RIEEG
Sbjct: 248 DNDMRTELQDLQMQANVVTDESLESTRRMLALCEESQDVGIKTIVMLDEQGEQLDRIEEG 69

Query: 64  MDQINKDMKEAEKN 77
           MDQIN+DMK+AEK 
Sbjct: 68  MDQINQDMKDAEKT 27
>07259
          Length = 993

 Score = 32.7 bits (73), Expect = 0.095,   Method: Compositional matrix adjust.
 Identities = 15/32 (46%), Positives = 21/32 (65%)
 Frame = +2

Query: 161 RHMALDMGNEIDTQNRQIDRIMEKADSNKTRI 192
           + MA+D+GNE+D Q+  ID I +  DS   RI
Sbjct: 74  KQMAIDIGNEVDLQDELIDDITDHVDSTGNRI 169
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|161086984|ref|NP_941015.2| adaptor-related protein
complex 2, sigma 1 subunit [Mus musculus]
         (142 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

04375                                                                 126   4e-30
05556                                                                  28   1.0  
14460                                                                  28   1.0  
16706                                                                  26   5.3  
03246                                                                  26   6.2  
25620                                                                  26   6.3  
24040                                                                  26   7.2  
03913                                                                  25   9.4  
>04375
          Length = 2667

 Score =  126 bits (316), Expect = 4e-30,   Method: Compositional matrix adjust.
 Identities = 55/121 (45%), Positives = 84/121 (69%)
 Frame = +3

Query: 15  RLAKWYMQFDDDEKQKLIEEVHAVVTVRDAKHTNFVEFRNFKIIYRRYAGLYFCICVDVN 74
           RL KWY+   D  K+K++ E+  +V  R  K  +F+E++  K++Y+RYA LYFC  ++  
Sbjct: 144 RLQKWYVAHPDKTKKKIVRELVTMVLSRKPKMCSFLEWKELKVVYKRYASLYFCCAIEPE 323

Query: 75  DNNLAYLEAIHNFVEVLNEYFHNVCELDLVFNFYKVYTVVDEMFLAGEIRETSQTKVLKQ 134
           DN L  LE IH +VE+L++YF +VCELD++FNF K + ++DE  L GE++ETS+  VLK 
Sbjct: 324 DNELLTLEIIHRYVELLDKYFGSVCELDIIFNFEKAFFMLDEFMLGGEVQETSKKNVLKA 503

Query: 135 L 135
           +
Sbjct: 504 I 506
>05556
          Length = 981

 Score = 28.5 bits (62), Expect = 1.0,   Method: Compositional matrix adjust.
 Identities = 18/48 (37%), Positives = 23/48 (47%), Gaps = 2/48 (4%)
 Frame = +1

Query: 14  TRLAKWYMQFDDDEKQKLIEEVHAVVT--VRDAKHTNFVEFRNFKIIY 59
           TR  K+ +QF  +  QK I      +T  VR   HT +  F N  IIY
Sbjct: 484 TRRTKYNLQF*FNNHQKFISYTFGKLTKFVRKVLHTKYSLFTNLSIIY 627
>14460
          Length = 1078

 Score = 28.5 bits (62), Expect = 1.0,   Method: Compositional matrix adjust.
 Identities = 18/48 (37%), Positives = 23/48 (47%), Gaps = 2/48 (4%)
 Frame = +2

Query: 14  TRLAKWYMQFDDDEKQKLIEEVHAVVT--VRDAKHTNFVEFRNFKIIY 59
           TR  K+ +QF  +  QK I      +T  VR   HT +  F N  IIY
Sbjct: 416 TRRTKYNLQF*FNNHQKFISYTFGKLTKFVRKVLHTKYSLFTNLSIIY 559
>16706
          Length = 401

 Score = 26.2 bits (56), Expect = 5.3,   Method: Compositional matrix adjust.
 Identities = 12/36 (33%), Positives = 20/36 (55%)
 Frame = +3

Query: 34 EVHAVVTVRDAKHTNFVEFRNFKIIYRRYAGLYFCI 69
           +H+ +T +  +HT+ V   NF I  R+Y   Y C+
Sbjct: 45 HIHSAMTPQPCQHTSQVLRNNFSINSRKYLQTY-CV 149
>03246
          Length = 832

 Score = 25.8 bits (55), Expect = 6.2,   Method: Compositional matrix adjust.
 Identities = 16/42 (38%), Positives = 23/42 (54%)
 Frame = -3

Query: 94  YFHNVCELDLVFNFYKVYTVVDEMFLAGEIRETSQTKVLKQL 135
           YF  V  LD    F+ ++ V + MFL  EIR+    K+L+ L
Sbjct: 491 YFGFVFILDGFPIFHLLFDVXE*MFLESEIRKVMTIKLLRSL 366
>25620
          Length = 850

 Score = 25.8 bits (55), Expect = 6.3,   Method: Compositional matrix adjust.
 Identities = 10/27 (37%), Positives = 16/27 (59%)
 Frame = -1

Query: 74  NDNNLAYLEAIHNFVEVLNEYFHNVCE 100
           NDNN++ +  IH  + ++   F  VCE
Sbjct: 634 NDNNISLMSKIHLMLSLITSIFLYVCE 554
>24040
          Length = 443

 Score = 25.8 bits (55), Expect = 7.2,   Method: Compositional matrix adjust.
 Identities = 11/29 (37%), Positives = 15/29 (51%)
 Frame = +3

Query: 44  AKHTNFVEFRNFKIIYRRYAGLYFCICVD 72
            KHTN V  R+  I  ++     FC C+D
Sbjct: 285 CKHTNQVSERSTNIHRKKILANTFCTCID 371
>03913
          Length = 1090

 Score = 25.4 bits (54), Expect = 9.4,   Method: Compositional matrix adjust.
 Identities = 10/45 (22%), Positives = 20/45 (44%)
 Frame = +1

Query: 41  VRDAKHTNFVEFRNFKIIYRRYAGLYFCICVDVNDNNLAYLEAIH 85
           V    HT         ++YR+ + ++ C C  + + +L   + IH
Sbjct: 415 VHGHTHTLIYSHTQSPLVYRKKSSVFCCCCCLLKNGDLKISKTIH 549
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31560370|ref|NP_064326.2| septin 6 [Mus musculus]
         (429 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

14132                                                                 128   4e-30
14677                                                                 125   2e-29
22078                                                                  67   9e-12
29788                                                                  64   2e-10
34156                                                                  59   4e-09
38061                                                                  56   3e-08
>14132
          Length = 422

 Score =  128 bits (322), Expect = 4e-30,   Method: Compositional matrix adjust.
 Identities = 61/139 (43%), Positives = 93/139 (66%), Gaps = 3/139 (2%)
 Frame = -2

Query: 105 FGDQINKEDSYKPIVEFIDAQFEAYLQEELKIRRVLHSYHDSRIHVCLYFIAPTGHSLKS 164
           FGD ++  + ++PI ++ID+++E YL  E ++ R +    D+R+H CLYFIAPTGH LK 
Sbjct: 421 FGDAVDNSNCWQPITDYIDSKYEEYLNAESRVNRTVMP--DTRVHCCLYFIAPTGHGLKP 248

Query: 165 LDLVTMKKLDSKVNIIPVIAKSDAISKSELAKFKIKITSELVSNGVQIYQFP-TDDESVS 223
           LD+  MK+L  KVNIIP++AK+D ++  E  +FK  I +E+  + ++IY+FP  DDE   
Sbjct: 247 LDVEFMKRLHDKVNIIPLVAKADTLTPDECREFKKTILNEIAQHKIKIYEFPDCDDEEEM 68

Query: 224 EINGTMNA--HLPFAVVGS 240
           +I   +     +PFAVVGS
Sbjct: 67  KIQKRLRVSDRVPFAVVGS 11
>14677
          Length = 378

 Score =  125 bits (315), Expect = 2e-29,   Method: Composition-based stats.
 Identities = 61/89 (68%), Positives = 72/89 (80%), Gaps = 7/89 (7%)
 Frame = -1

Query: 73  THTQP-------GVQLQSNTYDLQESNVGLKLTIVSTVGFGDQINKEDSYKPIVEFIDAQ 125
           T TQP        V+L+++TYDL E NV LKLT V T GFGDQINK DS+KPIV++IDAQ
Sbjct: 267 TLTQPQVLMTFLDVKLKAHTYDLTEKNVRLKLTTVDTTGFGDQINKADSWKPIVDYIDAQ 88

Query: 126 FEAYLQEELKIRRVLHSYHDSRIHVCLYF 154
           F+AYLQEELKI+R+LHSYHDSR+H CLYF
Sbjct: 87  FDAYLQEELKIKRMLHSYHDSRVHACLYF 1

 Score = 55.8 bits (133), Expect = 3e-08,   Method: Composition-based stats.
 Identities = 26/55 (47%), Positives = 34/55 (61%)
 Frame = -3

Query: 30  DQLVNKSVSQGFCFNILCVGETGLGKSTLMDTLFNTKFEGEPATHTQPGVQLQSN 84
           DQLV     +        +GETG+GKSTLMDTLFNT F+  P++H  PG Q + +
Sbjct: 376 DQLVTSLSLKASASTFFVLGETGIGKSTLMDTLFNTNFDSTPSSHDLPGRQTKGS 212
>22078
          Length = 417

 Score = 67.4 bits (163), Expect = 9e-12,   Method: Compositional matrix adjust.
 Identities = 26/48 (54%), Positives = 37/48 (77%)
 Frame = +3

Query: 252 RARQYPWGTVQVENEAHCDFVKLREMLIRVNMEDLREQTHARHYELYR 299
           R R YPWG V+V+N +HCDF++LR+MLI  +M+DL++ T   HYE +R
Sbjct: 3   RGRAYPWGIVEVDNXSHCDFIRLRQMLISTHMQDLKDVTSDVHYENFR 146
>29788
          Length = 687

 Score = 63.5 bits (153), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 38/94 (40%), Positives = 55/94 (58%), Gaps = 4/94 (4%)
 Frame = +3

Query: 257 PWGTVQVENEAHCDFVKLREMLIRVNMEDLREQTHARHYELYRRCKLEEMGFKDTDPDSK 316
           PWG V+VEN  H DF+ LR MLIR +M+DL++ T+  HYE +R  KL       T+   K
Sbjct: 3   PWGIVEVENLEHNDFIALRNMLIRTHMQDLKDVTNNVHYENFRYNKL---APSTTEGKVK 173

Query: 317 PFSLQE----TYEAKRNEFLGELQKKEEEMRQMF 346
           P +L +        +R E + +++K E EM Q+F
Sbjct: 174 PGALAKDPLSQMAEERQEHMVKMKKMEAEMEQVF 275
>34156
          Length = 348

 Score = 58.9 bits (141), Expect = 4e-09,   Method: Compositional matrix adjust.
 Identities = 32/79 (40%), Positives = 50/79 (63%), Gaps = 5/79 (6%)
 Frame = -1

Query: 29  PDQLVNKSVSQGFCFNILCVGETGLGKSTLMDTLFNTKFEGE-----PATHTQPGVQLQS 83
           P Q+  KSV +GF F ++ VGE+GLGKSTL+++LF T    E      +   Q  V++ +
Sbjct: 237 PTQVHRKSVKKGFEFTLMVVGESGLGKSTLVNSLFLTDLYPERHIPSASEKIQQTVKIDA 58

Query: 84  NTYDLQESNVGLKLTIVST 102
           +T +++E  V L+LT+V T
Sbjct: 57  STVEIEERGVKLRLTVVDT 1
>38061
          Length = 206

 Score = 55.8 bits (133), Expect = 3e-08,   Method: Composition-based stats.
 Identities = 23/30 (76%), Positives = 27/30 (90%)
 Frame = +3

Query: 229 MNAHLPFAVVGSTEEVKIGNKMMRARQYPW 258
           MN+HLPFAVVGS +EVKIGNKM++ARQ  W
Sbjct: 117 MNSHLPFAVVGSNDEVKIGNKMVKARQGSW 206
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|20072314|gb|AAH26481.1| Iqsec1 protein [Mus musculus]
         (548 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

30249                                                                 128   6e-30
20966                                                                  37   0.021
04419                                                                  32   0.64 
28727                                                                  29   6.1  
>30249
          Length = 822

 Score =  128 bits (321), Expect = 6e-30,   Method: Compositional matrix adjust.
 Identities = 74/160 (46%), Positives = 100/160 (62%), Gaps = 8/160 (5%)
 Frame = -2

Query: 205 EAQKVERLIEAFSQRYCVCNPGVVRQFRNPDTXXXXXXXXXXXNTDMYSPNVKPERKMKL 264
           EAQK+ERL+EAF++RYC CNP  V+ F+  DT           NTD+++ +VKPERKMKL
Sbjct: 821 EAQKIERLMEAFAERYCQCNPDQVKNFKTFDTVFLLAFAIIMLNTDLHNSSVKPERKMKL 642

Query: 265 EDFVKNLRGVDDGEDIPRETLIGIYERIRKRELKTNEDHVSQVQKVEKLIVGK-KPIGSL 323
           EDFV+NLRG+DDGED+  +        +  R+L+ N+   + VQ       G+ +P  + 
Sbjct: 641 EDFVRNLRGIDDGEDVDGD--------LASRDLRANQ--AAGVQ-------GRGRPGHAG 513

Query: 324 HHGLG--C-----VLSLPHRRLVCYCRLFEVPDPNKPQKL 356
           H G    C      L+L HRRLVCYCRL+EV DPNK ++L
Sbjct: 512 HEGRTDHCGWQEPQLALSHRRLVCYCRLYEVHDPNKRKRL 393

 Score =  110 bits (274), Expect = 2e-24,   Method: Compositional matrix adjust.
 Identities = 76/205 (37%), Positives = 103/205 (50%), Gaps = 9/205 (4%)
 Frame = -3

Query: 269 KNLRGVDDGEDIPR----ETLIGIYERIRKRELKTNEDHVSQVQKVEKLIV-GKKPIGSL 323
           K L G  +G    R      L GIYERI+++E K   D V+QV KVE+ IV GK P    
Sbjct: 640 KTLSGTSEGLTTGRMWTGTWLAGIYERIKQQEFKAGVDQVTQVMKVEQTIVGGKNPNWPC 461

Query: 324 HHGLGCVLSLPHRRLVCYCRLFEVPDPNKPQKLGLHQREIFL----FNDLLVVTKIFQKK 379
             G  C      R +           P K +      R + +      D     +  Q+K
Sbjct: 460 LTGAWCATVACTRSMT----------PTKGKDWSAPTRSLPV*RHSSGD-----ENLQQK 326

Query: 380 KNSVTYSFRQSFSLYGMQVLLFENQYYPNGIRLTSAVPGADIKVLINFNAPNPQDRKKFT 439
           K  +TY+F+ S SL GMQV LFE  +Y  G++LT+ +   D K LI FNA N  DR+KF 
Sbjct: 325 KTGITYNFKISLSLCGMQVYLFETPHYHYGVQLTNNI---DSKPLITFNARNDHDRQKFV 155

Query: 440 DDLRESVAEVQEMEKHRIESELEKQ 464
           +DL+ES+ E   ME+ RIE E+ + 
Sbjct: 154 EDLKESILETNGMEQLRIEEEMHRH 80
>20966
          Length = 686

 Score = 37.0 bits (84), Expect = 0.021,   Method: Compositional matrix adjust.
 Identities = 19/43 (44%), Positives = 25/43 (58%), Gaps = 2/43 (4%)
 Frame = -3

Query: 108 IRKRHYRIGLNLFNKKPEKGIQYLIERGFV--PDTPVGVAHFL 148
            ++R Y  G   FN+KP KGI +L E+G +  P  P  VA FL
Sbjct: 150 TKERAYNQGTEYFNQKPAKGIAFLQEQGLLATPXDPGQVATFL 22
>04419
          Length = 1176

 Score = 32.0 bits (71), Expect = 0.64,   Method: Compositional matrix adjust.
 Identities = 20/52 (38%), Positives = 27/52 (51%), Gaps = 4/52 (7%)
 Frame = -3

Query: 327  LGCVLSLPHRRLVCYCRLFEVPDPNKP----QKLGLHQREIFLFNDLLVVTK 374
            LGC+ ++PH RL C   LF    P  P      + LH   IF+F D + VT+
Sbjct: 1087 LGCLKTIPHIRL-CIFFLFS*GPPFYPVSFMMSVSLHVCAIFMFIDFVSVTR 935
>28727
          Length = 1088

 Score = 28.9 bits (63), Expect = 6.1,   Method: Compositional matrix adjust.
 Identities = 15/39 (38%), Positives = 23/39 (58%)
 Frame = +3

Query: 447 AEVQEMEKHRIESELEKQKGVVRPSMSQCSSLKKESGNG 485
           A V E     + + LE+ K V + +M   +SLKK++GNG
Sbjct: 396 AIVDEHLSMXLHTNLERSKSVSQNAMHSLASLKKKNGNG 512
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|110835702|ref|NP_666082.2| coiled-coil and C2 domain
containing 1A [Mus musculus]
         (943 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

13613                                                                 129   7e-30
37035                                                                  86   5e-17
31647                                                                  60   4e-09
13454                                                                  44   3e-04
>13613
          Length = 577

 Score =  129 bits (323), Expect = 7e-30,   Method: Composition-based stats.
 Identities = 64/160 (40%), Positives = 104/160 (65%)
 Frame = -1

Query: 675 VRFDFPYPNVEEAQKDKTSVIKNTDSPEFKEQFKLCINRGHRGFRRAIQTKGIKFEVVHK 734
           V+++F +P+ ++ Q   +S +K+T +PE+ EQFKL I+R  R F R ++ KGIK +V  K
Sbjct: 559 VKYEFAFPS-DDGQTGHSSTVKDTINPEYNEQFKLMIDRKSRSFARVVERKGIKLDVYIK 383

Query: 735 GGLFKTDRVLGTAQLKLGTLETACEVHEILEVLDGRRPTGGRLEVMVRIREPLTAQQLET 794
            G FK D++LG+A +KL  LE+ C +H+  ++++GR+  GG+LEV VR+R+P   +Q+E 
Sbjct: 382 RGFFKGDKLLGSATVKLNPLESKCVLHDSFDLMEGRKSVGGKLEVKVRVRDPFKGRQVEE 203

Query: 795 TTERWLVIDHIPAAMPTVTGPKAKAPLIPASSREAGNRSA 834
           + E+WLVID     M    G K++A    A+S +    S+
Sbjct: 202 SKEKWLVIDQFIRTM----GSKSQAGQASAASSKPKKESS 95
>37035
          Length = 531

 Score = 86.3 bits (212), Expect = 5e-17,   Method: Composition-based stats.
 Identities = 37/103 (35%), Positives = 64/103 (62%)
 Frame = +1

Query: 716 RGFRRAIQTKGIKFEVVHKGGLFKTDRVLGTAQLKLGTLETACEVHEILEVLDGRRPTGG 775
           R   R ++ KGIK  +  K G  + +++LG+  +KL +L+T C +H+  ++ DGR+  GG
Sbjct: 1   RSLARFVERKGIKLXIYIKRGFLRGEQLLGSTSVKLSSLDTXCTLHDSFDLADGRKSVGG 180

Query: 776 RLEVMVRIREPLTAQQLETTTERWLVIDHIPAAMPTVTGPKAK 818
           +LEV VR+R+P   + +E + E+WLVID    ++ +    KA+
Sbjct: 181 KLEVKVRVRDPFKGRHVEESQEKWLVIDQFIRSLASHPASKAQ 309
>31647
          Length = 318

 Score = 60.5 bits (145), Expect = 4e-09,   Method: Compositional matrix adjust.
 Identities = 29/98 (29%), Positives = 59/98 (60%), Gaps = 4/98 (4%)
 Frame = -3

Query: 526 MLEASRNGLPVDIAKVPPAPV----NKDDFVLVQRPGPGLSQEAVRRYGELTKLLRQQHE 581
           M+EA  +GLPVD+++VPP+P+     +D +V+V       + +    + +L + + +Q +
Sbjct: 298 MIEALESGLPVDLSQVPPSPLENEETEDKYVVVSADDCQPTGDRDELFTQLEQDMVKQIQ 119

Query: 582 MCLNHSTQFTHLGNIAETIKFEKLAEDCKRSMDTLKQA 619
            C  ++  FT LG++    KF+K+ + C++ +++LK A
Sbjct: 118 TCATNAQHFTKLGDVPAASKFQKMEQGCRKDLESLKSA 5
>13454
          Length = 583

 Score = 43.9 bits (102), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 17/46 (36%), Positives = 31/46 (67%)
 Frame = +1

Query: 258 HEYKLAALRAKHQDDTATATRHLRIAKSFDPVLEALSRGELVDLSR 303
           ++YKL A++AK    T  A +H+R+ K    +L+A+ +GE VD+++
Sbjct: 205 NQYKLEAMKAKRSGQTEVALQHMRVVKGLQSLLQAMDKGETVDMTQ 342

 Score = 39.7 bits (91), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 21/53 (39%), Positives = 30/53 (56%)
 Frame = +1

Query: 493 RKKQLLQAALRAKQKNDVEGAKMHLRQAKGLEPMLEASRNGLPVDIAKVPPAP 545
           R  Q    A++AK+    E A  H+R  KGL+ +L+A   G  VD+ +VPP P
Sbjct: 199 RCNQYKLEAMKAKRSGQTEVALQHMRVVKGLQSLLQAMDKGETVDMTQVPPPP 357
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|149258722|ref|XP_357872.6| PREDICTED: hypothetical
protein LOC78506 isoform 1 [Mus musculus]
         (523 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

33397                                                                  82   7e-30
05237                                                                  32   0.66 
01019                                                                  32   0.77 
25447                                                                  31   1.1  
26019                                                                  30   2.4  
16255                                                                  30   3.1  
14594                                                                  29   4.4  
>33397
          Length = 1723

 Score = 81.6 bits (200), Expect(2) = 7e-30,   Method: Compositional matrix adjust.
 Identities = 50/156 (32%), Positives = 80/156 (51%), Gaps = 16/156 (10%)
 Frame = +2

Query: 384 FAHILLRYTNV--ENTSVFLENVRYSISEE-KGITFDEFRSFFQFLNNLEDFAIALNMYN 440
           F  ILL Y  +  +  +  L+ V+   SEE KGI+F+E+ +F++FL ++ D   AL+ Y+
Sbjct: 509 FGSILLTYAGLPSKKMARMLKRVKRKFSEEPKGISFEEYLAFWKFLKSINDIDTALSFYH 688

Query: 441 FASRSIGQDEFKRAVYVATGLKLSPHLVNTVFKIFDVDKDDQLSYKEFIGIMKDRLHRGF 500
            A  SI ++ F           L+ H+++ VF +FD + D +LS KEF+ +MK R+ RG 
Sbjct: 689 LAGVSIDRETFHHVAKTVAMADLTEHVIDVVFTLFDENNDGELSNKEFVSVMKRRVMRGL 868

Query: 501 RG-------------YKTVQKYPTFKSCLKKELHSR 523
                          +K      TF     K+LHS+
Sbjct: 869 EKPKDTGFVKVLNAVWKCASSTTTFLD*TCKQLHSQ 976

 Score = 67.4 bits (163), Expect(2) = 7e-30,   Method: Compositional matrix adjust.
 Identities = 55/194 (28%), Positives = 79/194 (40%), Gaps = 2/194 (1%)
 Frame = +3

Query: 181 KQELSQMLSETP--PVWKGSSKLFRNLKERGVISYTEYLFLLCILTKPHAGFRIAFNMFD 238
           K  L  + S  P  P       +F  L E G+IS+++Y+FLL +L+ P   F IAF MFD
Sbjct: 45  KDSLRDLKSRIPREPTNISEDSIFYKLGEHGLISFSDYIFLLTVLSTPPRNFEIAFRMFD 224

Query: 239 TDGNEMVDKKEFLVLQEIFRKKNEKRETKGDEEKRAMLRLQLYGYHSPTNSVLKTDAGEL 298
            +G+  +D +EF  +Q + R +        D              H+ T SV   D G  
Sbjct: 225 INGDGELDLEEFNRVQGVIRNQTHVGARHRD--------------HAVTGSV---DHG-- 347

Query: 299 VSRSYWDTLRRSTSQALFSDLAERADDITSLVADTTLLVHFFGKKGKAELNFEDFYRFMD 358
                                             ++LL +FFGK GK +L  ++F  F  
Sbjct: 348 --------------------------------LSSSLLSYFFGKNGKKKLTHKEFLDFQR 431

Query: 359 NLQTEVLEIEFLSY 372
            LQ E+  IEF  Y
Sbjct: 432 QLQREINRIEFERY 473
>05237
          Length = 472

 Score = 32.0 bits (71), Expect = 0.66,   Method: Compositional matrix adjust.
 Identities = 14/40 (35%), Positives = 24/40 (60%)
 Frame = +3

Query: 453 RAVYVATGLKLSPHLVNTVFKIFDVDKDDQLSYKEFIGIM 492
           R V    G KL+   V+ + +  D+D D Q++Y+EF+ +M
Sbjct: 96  RHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVKMM 215
>01019
          Length = 1705

 Score = 31.6 bits (70), Expect = 0.77,   Method: Compositional matrix adjust.
 Identities = 14/43 (32%), Positives = 25/43 (58%)
 Frame = +1

Query: 453 RAVYVATGLKLSPHLVNTVFKIFDVDKDDQLSYKEFIGIMKDR 495
           R V    G KL+   V+ + +  D+D D Q++Y+EF+ +M  +
Sbjct: 88  RHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVTMMTSK 216
>25447
          Length = 494

 Score = 31.2 bits (69), Expect = 1.1,   Method: Composition-based stats.
 Identities = 12/32 (37%), Positives = 22/32 (68%)
 Frame = -3

Query: 419 FRSFFQFLNNLEDFAIALNMYNFASRSIGQDE 450
           + SF+ FL +L  F +A+++Y    RSIG+++
Sbjct: 489 YYSFYVFLAHLVTFTLAVHLYTLLVRSIGKNQ 394
>26019
          Length = 1561

 Score = 30.0 bits (66), Expect = 2.4,   Method: Compositional matrix adjust.
 Identities = 26/85 (30%), Positives = 39/85 (45%), Gaps = 2/85 (2%)
 Frame = +2

Query: 199 SKLFR--NLKERGVISYTEYLFLLCILTKPHAGFRIAFNMFDTDGNEMVDKKEFLVLQEI 256
            K FR  +L   G +S  E++ L  +   P    +   ++FDTDGN  VD KEF+     
Sbjct: 107 GKRFRKLDLDNSGSLSIDEFMSLPELQQNPLV--QRVIDIFDTDGNGEVDFKEFIEGISQ 280

Query: 257 FRKKNEKRETKGDEEKRAMLRLQLY 281
           F         KGD+E +     ++Y
Sbjct: 281 F-------SVKGDKESKLRFAFKIY 334
>16255
          Length = 767

 Score = 29.6 bits (65), Expect = 3.1,   Method: Compositional matrix adjust.
 Identities = 12/33 (36%), Positives = 22/33 (66%)
 Frame = -2

Query: 460 GLKLSPHLVNTVFKIFDVDKDDQLSYKEFIGIM 492
           G KL+   V+ + +  D+D D Q++Y+EF+ +M
Sbjct: 754 GEKLTDEEVDEMIREADIDGDGQVNYEEFVTMM 656
>14594
          Length = 1014

 Score = 29.3 bits (64), Expect = 4.4,   Method: Compositional matrix adjust.
 Identities = 14/40 (35%), Positives = 23/40 (57%)
 Frame = +3

Query: 453 RAVYVATGLKLSPHLVNTVFKIFDVDKDDQLSYKEFIGIM 492
           R V    G KL+   V+ + K  D+D D  ++Y+EF+ +M
Sbjct: 729 RHVMTNLGEKLTDEEVDEMIKEADLDGDGMVNYEEFVTMM 848
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|66730565|ref|NP_001019377.1| trafficking protein
particle complex 1 [Mus musculus]
         (145 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

18767                                                                 125   7e-30
18428                                                                  33   0.029
17679                                                                  29   0.68 
00976                                                                  27   2.6  
30827                                                                  26   4.6  
>18767
          Length = 467

 Score =  125 bits (313), Expect = 7e-30,   Method: Compositional matrix adjust.
 Identities = 52/78 (66%), Positives = 72/78 (92%)
 Frame = -3

Query: 1   MTVHNLYLFDRNGVCLHYSEWHRKKQAGIPKEEEYKLMYGMLFSIRSFVSKMSPLDMKDG 60
           MTV++ YLFDRNG CL+Y+EW+RK Q GI K+EE+KLMYGM+FSI+SF++++SP D++DG
Sbjct: 234 MTVYDFYLFDRNGNCLYYAEWNRKNQPGISKDEEFKLMYGMIFSIKSFINRISPKDVQDG 55

Query: 61  FLSFQTSRYKLHYYETPT 78
           FL+F+TS+YKLH+YETP+
Sbjct: 54  FLNFKTSKYKLHFYETPS 1
>18428
          Length = 705

 Score = 33.5 bits (75), Expect = 0.029,   Method: Compositional matrix adjust.
 Identities = 21/62 (33%), Positives = 31/62 (50%), Gaps = 2/62 (3%)
 Frame = -1

Query: 28  GIPK--EEEYKLMYGMLFSIRSFVSKMSPLDMKDGFLSFQTSRYKLHYYETPTGIKVVMN 85
           G PK    E  ++  M  S+ +   ++SP     G    +T  +KLH  +T TGIK V+ 
Sbjct: 216 GRPKLTTNEKIMLASMFHSLFAIGCQLSPEPRSSGIQVLETETFKLHCEQTMTGIKFVVI 37

Query: 86  TD 87
           TD
Sbjct: 36  TD 31
>17679
          Length = 509

 Score = 29.3 bits (64), Expect = 0.68,   Method: Compositional matrix adjust.
 Identities = 17/52 (32%), Positives = 26/52 (50%), Gaps = 1/52 (1%)
 Frame = -2

Query: 45  IRSFVSKMSPLDMKDGFLSFQTSRYKLH-YYETPTGIKVVMNTDLGVGPIRD 95
           +RS+   +SP       L+   S  KL  +Y TP  ++  M  D+G GPI +
Sbjct: 508 VRSWAHPISPGSR----LASMGSACKLRGWYGTPCVVRTWMGWDMGPGPIEE 365
>00976
          Length = 1227

 Score = 27.3 bits (59), Expect = 2.6,   Method: Compositional matrix adjust.
 Identities = 15/56 (26%), Positives = 27/56 (48%), Gaps = 1/56 (1%)
 Frame = +2

Query: 19  SEWHRKKQAGIPKEEEYKLMYGMLFSIRSFVSKMSPLDMKD-GFLSFQTSRYKLHY 73
           S W   +Q+   +  +Y   +      R+  +KMSP+  K+   +    SR+KL+Y
Sbjct: 296 SSWTVDQQSSQTRAPQYNFHFNTCKPQRTVFTKMSPVFKKNLPIVYVSNSRFKLNY 463
>30827
          Length = 665

 Score = 26.2 bits (56), Expect = 4.6,   Method: Compositional matrix adjust.
 Identities = 11/29 (37%), Positives = 16/29 (55%)
 Frame = -3

Query: 15  CLHYSEWHRKKQAGIPKEEEYKLMYGMLF 43
           C+H +  H +K AGIP    +  MY + F
Sbjct: 549 CIHMAVQHTRKHAGIP-LHTHNYMYNLCF 466
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|10946722|ref|NP_067358.1| rcd1 (required for cell
differentiation) homolog 1 [Mus musculus]
         (299 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

07921                                                                 117   8e-30
16028                                                                 113   1e-25
02158                                                                  92   4e-19
15301                                                                  69   3e-12
18435                                                                  33   0.20 
12065                                                                  28   5.5  
>07921
          Length = 910

 Score =  117 bits (292), Expect(2) = 8e-30,   Method: Compositional matrix adjust.
 Identities = 69/201 (34%), Positives = 116/201 (57%), Gaps = 4/201 (1%)
 Frame = -3

Query: 25  WINELSSPETRENALLELSKKRESVPDLAPMLWHSFGTIAALLQEIVNIY----PSINPP 80
            I +L     R+ AL  L   + SVP+L  +L     ++A+LL+EI +++    P  NPP
Sbjct: 710 LIRDLGDKSKRKTALSHLVSFQRSVPNLGSLLG---ASVASLLEEIQSVFIAVTPPANPP 540

Query: 81  TLTAHQSNRVCNALALLQCVASHPETRSAFLAAHIPLFLYPFLHTVSKTRPFEYLRLTSL 140
             T  Q+  V NAL+LL+ VA HP+TR AF+ +++   L PFL +V K+     LR+ S+
Sbjct: 539 GPTTEQARSVHNALSLLKHVAVHPDTRPAFIQSNMISHLTPFLMSVDKSSNIRALRIASI 360

Query: 141 GVIGALVKTDEQEVINFLLTTEIIPLCLRIMESGSELSKTVATFILQKILLDDTGLAYIC 200
            ++ ALV+T+ Q+V+  L++  I      ++ SG E+ KT  T++++++L ++ GL ++C
Sbjct: 359 RLLHALVQTESQDVMLHLISVNIFHQLFSLINSGCEVCKTSGTYVMRRLLQEEYGLTFVC 180

Query: 201 QTYERFSHVAMILGKMVLQLS 221
           +   R       L   VLQL+
Sbjct: 179 EHPMRLLQAVHCLHMPVLQLA 117

 Score = 30.8 bits (68), Expect(2) = 8e-30,   Method: Compositional matrix adjust.
 Identities = 12/27 (44%), Positives = 19/27 (70%)
 Frame = -1

Query: 228 LLKHVVRCYLRLSDNPRAREALRQCLP 254
           LL+HV+RCY  L+ +PR  + ++  LP
Sbjct: 91  LLEHVLRCYALLASDPRGLQVIKDNLP 11
>16028
          Length = 879

 Score =  113 bits (282), Expect = 1e-25,   Method: Compositional matrix adjust.
 Identities = 55/86 (63%), Positives = 66/86 (76%), Gaps = 4/86 (4%)
 Frame = +3

Query: 217 VLQLSKEPSARLLKHVVRCYLRLSDNPRAREALRQCLPDQLKDTTFAQVLKDDTTTKRWL 276
           V+QLSKEP ARLLKHVVRCYLRLSDN RAR+AL QCLPDQL+D TF + L++D +TK+WL
Sbjct: 3   VIQLSKEPCARLLKHVVRCYLRLSDNTRARKALGQCLPDQLRDGTFTECLQNDKSTKQWL 182

Query: 277 AQLVKNLQEGQV----TDPRGIPLPP 298
             L+KNL+ G       DPR I + P
Sbjct: 183 QMLIKNLEPGATQALGGDPRQIGMSP 260
>02158
          Length = 871

 Score = 91.7 bits (226), Expect = 4e-19,   Method: Compositional matrix adjust.
 Identities = 53/180 (29%), Positives = 101/180 (56%), Gaps = 2/180 (1%)
 Frame = -3

Query: 106 TRSAFLAAHIPLFLYPFLHTVSKTRPFEYLRLTSLGVIGALVKTDEQEVINFLLTTEIIP 165
           TR AFL + +  FL PFL +  ++   + LR+ S+ ++ +LV+T+ Q+V+ +L++T+I  
Sbjct: 869 TRPAFLQSCMVSFLKPFLLSFDQSPNTQALRVVSVRILDSLVQTESQDVLQYLISTDIFN 690

Query: 166 LCLRIMESGSELSKTVATFILQKILLDDTGLAYICQTYERFSHVAMILGKMVLQLSKE-- 223
               ++ +  E+    A +I++++L +D GL Y+C+   +       L  +V++LS E  
Sbjct: 689 ELFTLIYTKCEVCS--AVYIMRRLLQEDYGLTYVCENELKLQQAVQCLHMVVVRLSPEEC 516

Query: 224 PSARLLKHVVRCYLRLSDNPRAREALRQCLPDQLKDTTFAQVLKDDTTTKRWLAQLVKNL 283
           P + LL+H +RCY  LS NPR    ++  LP  + +    ++L   +  + +  QL+  L
Sbjct: 515 PQSVLLEHALRCYSLLSSNPRGLMCIKTHLPSPIINGLIQRLLVSGSNAELFYNQLISRL 336
>15301
          Length = 888

 Score = 68.6 bits (166), Expect = 3e-12,   Method: Compositional matrix adjust.
 Identities = 41/162 (25%), Positives = 79/162 (48%), Gaps = 2/162 (1%)
 Frame = +1

Query: 121 PFLHTVSKTRPFEYLRLTSLGVIGALVKTDEQEVINFLLTTEIIPLCLRIMESGSELSKT 180
           PFL TV++    E LRLTS+ ++  +++T    V+   +   I      ++    E  +T
Sbjct: 22  PFLKTVNEAHALECLRLTSVIMLEDMIRTGRPNVLECFVDNGIFECTFSLIHIAGEKCRT 201

Query: 181 VATFILQKILLDDTGLAYICQTYERFSHVAMILGKMVLQL--SKEPSARLLKHVVRCYLR 238
            ATF++  +L   +GL  +  +  R  +    L  +V+ L  +  P   L+ +V+RCY R
Sbjct: 202 XATFVMWIMLNMGSGLQRVVSSPSRLRNAVHCLTSVVIYLAYADSPDPELVANVLRCYCR 381

Query: 239 LSDNPRAREALRQCLPDQLKDTTFAQVLKDDTTTKRWLAQLV 280
           L+ + RA   +R+ LP Q  +     ++   +    + ++L+
Sbjct: 382 LATDARALRCIRRNLPKQFVNGQMKGLVTKGSLADFYFSRLI 507
>18435
          Length = 675

 Score = 32.7 bits (73), Expect = 0.20,   Method: Compositional matrix adjust.
 Identities = 16/37 (43%), Positives = 21/37 (56%)
 Frame = +3

Query: 43  SKKRESVPDLAPMLWHSFGTIAALLQEIVNIYPSINP 79
           S  R  V  L  +L HSFGT+     EI  ++PS+NP
Sbjct: 282 SSDRLRVNGLLVILHHSFGTLCHPTLEICQLFPSLNP 392
>12065
          Length = 1251

 Score = 27.7 bits (60), Expect = 5.5,   Method: Compositional matrix adjust.
 Identities = 15/39 (38%), Positives = 22/39 (56%)
 Frame = +3

Query: 60  FGTIAALLQEIVNIYPSINPPTLTAHQSNRVCNALALLQ 98
           F  +++L Q+   + P  NPPT+T   S R  N L L+Q
Sbjct: 426 FCVLSSLXQQGFCL-PVFNPPTMTLSASARDVNGLVLMQ 539
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|87252727|ref|NP_067312.2| superkiller viralicidic
activity 2-like [Mus musculus]
         (1244 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

13828                                                                 129   8e-30
14209                                                                  36   0.099
>13828
          Length = 2681

 Score =  129 bits (324), Expect = 8e-30,   Method: Compositional matrix adjust.
 Identities = 82/284 (28%), Positives = 134/284 (47%), Gaps = 2/284 (0%)
 Frame = +2

Query: 961  TAVQELLRLAQSYPAGPPTLDPINDLQLKDVAVVEGGLRARKLEELIRGAQCVHSPRFPA 1020
            + ++ L  + + +  G P LDP+ D+ +K+  + +   +    E  +         R   
Sbjct: 380  SVLKSLQEVEKRFEDGVPVLDPLEDMGIKEKGLHDVIKKTEAFEHRLHTHPLHKDXRLDX 559

Query: 1021 QYVKLRERMQIQKEMEXXXXXXXXXXXX-XXPEYHQRVEVLRTLGYVDEAGTVKLAGRVA 1079
             Y    ++     E++                E   R  VLR LGY   +  ++  GRVA
Sbjct: 560  LYNSYEKKTSWANEIKALRLELKKKKSLLQMDELKCRKRVLRRLGYATASDVIETKGRVA 739

Query: 1080 CAMSS-HELLLTELMFDNALSALRPEEIAALLSGLVCQSPGDPGDQLPSTLKQGVERVKA 1138
            C +SS  EL++TEL+F+N  + L P +  ALLS  V Q       +L   L   +  ++ 
Sbjct: 740  CEISSGDELVITELLFNNVFNDLSPAQCCALLSCFVFQERASETPKLIEELSGPLRLMQE 919

Query: 1139 VAKRIGEVQVACGLNQTVEEFVGELNFGLVEVVYEWARGMPFSELAGLSGTPEGLVVRCI 1198
             AKRI  V     L    +++V      ++++VYEW  G  FS++  ++   EG V+RC+
Sbjct: 920  TAKRIARVSKEAKLEIDEDQYVESFRPQMMDIVYEWCNGCSFSKICKMTDIFEGSVIRCM 1099

Query: 1199 QRLAEMCRSLRGAARLVGEPVLGAKMETAATLLRRDIVFAASLY 1242
            +RL E  R +  A++ +G   L  K      L++RDIVFAASLY
Sbjct: 1100 RRLEETLRQMVQASKAIGNTELENKFAEGIRLIKRDIVFAASLY 1231
>14209
          Length = 424

 Score = 35.8 bits (81), Expect = 0.099,   Method: Compositional matrix adjust.
 Identities = 19/57 (33%), Positives = 26/57 (45%)
 Frame = -1

Query: 151 QYPFWPGGMDEPSITDLHTRXXXXXXIDFEKDLLTVPPGFKKGVDFAPKDHPAPVPG 207
           + PF P  + +     +H +       D E  LLT  P  ++GVD    DH AP PG
Sbjct: 205 KQPFLPVKVTDKVFKSVHAKGRGITRADMEAALLTFKPSMQRGVDCI-VDHSAPCPG 38
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|19527224|ref|NP_598763.1| casein kinase 1, gamma 2
[Mus musculus]
         (442 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

18481                                                                 127   9e-30
16959                                                                 110   1e-24
30755                                                                  53   3e-07
32357                                                                  49   3e-06
01718                                                                  48   6e-06
26560                                                                  47   1e-05
29581                                                                  47   2e-05
21433                                                                  46   3e-05
09606                                                                  45   5e-05
00300                                                                  45   7e-05
01106                                                                  44   1e-04
14126                                                                  44   1e-04
01060                                                                  44   1e-04
26711                                                                  44   1e-04
21079                                                                  44   1e-04
04591                                                                  44   2e-04
01707                                                                  43   2e-04
01966                                                                  43   3e-04
11780                                                                  43   3e-04
27405                                                                  42   6e-04
11185                                                                  41   0.001
18921                                                                  40   0.001
01756                                                                  40   0.002
01392                                                                  40   0.003
26009                                                                  40   0.003
03240                                                                  39   0.004
31885                                                                  39   0.005
15910                                                                  39   0.005
03508                                                                  39   0.005
00715                                                                  38   0.008
19094                                                                  38   0.009
04852                                                                  37   0.012
16708                                                                  36   0.034
19761                                                                  36   0.040
07940                                                                  35   0.057
21800                                                                  35   0.077
28157                                                                  35   0.087
04138                                                                  34   0.092
13066                                                                  34   0.11 
27546                                                                  33   0.20 
12786                                                                  33   0.28 
14477                                                                  32   0.39 
19301                                                                  32   0.40 
14116                                                                  32   0.49 
31489                                                                  32   0.60 
17975                                                                  29   3.2  
32359                                                                  28   7.0  
>18481
          Length = 437

 Score =  127 bits (319), Expect = 9e-30,   Method: Compositional matrix adjust.
 Identities = 68/171 (39%), Positives = 102/171 (59%)
 Frame = -1

Query: 63  GKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLSTTGEADSGTGPALLGQQWLRTPSMD 122
           G N    + +A+K+E I  +   LH E + Y+Q+                    R P   
Sbjct: 428 GYNTQDGKDIAVKIEAIDVKHQLLHYEAKVYEQIG-------------------RHP--- 315

Query: 123 VSFAEGVPQVYYFGPCGKYNAMVLELLGPSLEDLFDLCDRTFTLKTVLMIAIQLITRMEY 182
                G+P +Y++G    +NA+V+ELLGPSLE+LF +C R FTLKT+LM++ QL++R+E+
Sbjct: 314 -----GLPTMYHYGTEKHFNALVMELLGPSLEELFVICKRRFTLKTILMVSDQLLSRLEF 150

Query: 183 VHTKSLIYRDVKPENFLVGRPGSKRQHSIHIIDFGLAKEYIDPETKKHIPY 233
           +H K  I+RD+KP+NFL+G    +  H ++IIDFGL+K Y D +   HIPY
Sbjct: 149 IHQKCFIHRDLKPDNFLMGL--GRHCHRLYIIDFGLSKRYKDTQGTMHIPY 3
>16959
          Length = 1747

 Score =  110 bits (274), Expect = 1e-24,   Method: Compositional matrix adjust.
 Identities = 52/94 (55%), Positives = 67/94 (71%)
 Frame = -1

Query: 263  EALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCESFPEEMATYLRYVR 322
            EALG++ MYF RGSLPWQGLKA T K++ ++I + K ATP++ LC+SFP E + +L Y R
Sbjct: 1747 EALGYVLMYFNRGSLPWQGLKAATKKQKCERISEKKIATPVDSLCKSFPSEFSIFLNYSR 1568

Query: 323  RLDFFEKPDYDYLRKLFTDLFDRSGYVFDYEYDW 356
             L F E PDY YLR+LF  LF    + FDY +DW
Sbjct: 1567 DLRFDEGPDYTYLRQLFRVLFRTYNHHFDYAFDW 1466
>30755
          Length = 1137

 Score = 52.8 bits (125), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 37/128 (28%), Positives = 58/128 (45%), Gaps = 1/128 (0%)
 Frame = +2

Query: 161 DRTFTLKTVLMIAIQLITRMEYVHTKSLIYRDVKPENFLVGRPGSKRQHSIHIIDFGLAK 220
           +R FT +       ++I+ + Y+H++ +IYRD+K EN L+ + G      I + DFGL K
Sbjct: 14  ERIFTEERTRFYGAEIISALGYLHSQGIIYRDLKLENLLLDKDG-----HIKVADFGLCK 178

Query: 221 EYIDPETKKHIPY-REHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPW 279
           E         I Y R  K+  GT  Y++       +  R  D    G +    + G LP+
Sbjct: 179 E--------DITYGRTTKTFCGTPEYLAPEVLDDNDYGRAVDWWGTGVVMYEMICGRLPF 334

Query: 280 QGLKADTL 287
                D L
Sbjct: 335 YNRDHDVL 358
>32357
          Length = 625

 Score = 49.3 bits (116), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 25/57 (43%), Positives = 38/57 (66%)
 Frame = -2

Query: 40  LMVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQL 96
           L+V   +R+ KKIG G+FGE+ LG +  + E VA+KLE   ++ PQL+ E + Y+ L
Sbjct: 450 LLVNGKYRLMKKIGSGSFGEIYLGVHNTSGEEVAVKLELKNAKHPQLYYESKLYRVL 280

 Score = 47.8 bits (112), Expect = 8e-06,   Method: Compositional matrix adjust.
 Identities = 23/49 (46%), Positives = 28/49 (57%)
 Frame = -1

Query: 141 YNAMVLELLGPSLEDLFDLCDRTFTLKTVLMIAIQLITRMEYVHTKSLI 189
           YN MV++LLGPSLEDLF+ C R FT+K       +  T   Y    S I
Sbjct: 229 YNVMVMDLLGPSLEDLFNYCGRKFTMKQCSCSQTR*STGWNYTQQTSFI 83

 Score = 38.5 bits (88), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 17/32 (53%), Positives = 27/32 (84%)
 Frame = -3

Query: 167 KTVLMIAIQLITRMEYVHTKSLIYRDVKPENF 198
           +TVLM+A Q+I R+E ++T + I+RD+KP+NF
Sbjct: 152 ETVLMLADQMINRLE-LYTTNFIHRDLKPDNF 60
>01718
          Length = 959

 Score = 48.1 bits (113), Expect = 6e-06,   Method: Compositional matrix adjust.
 Identities = 37/148 (25%), Positives = 70/148 (47%), Gaps = 3/148 (2%)
 Frame = +3

Query: 134 YFGPC---GKYNAMVLELLGPSLEDLFDLCDRTFTLKTVLMIAIQLITRMEYVHTKSLIY 190
           + G C   G+ +A+   +   +LE L +  D        + + + L   ++Y+H+   I+
Sbjct: 327 FMGVCVHEGQLHALTEYIPSGNLEQLLEKKDEELPWTQRIQLTLGLARGLDYLHSTRFIH 506

Query: 191 RDVKPENFLVGRPGSKRQHSIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINT 250
           RD+  +N L+ R  +   H++ I DFGLA +  DP  K+ +P        G+  +M+   
Sbjct: 507 RDLTSKNILIRREDNHGYHAV-IADFGLATKIPDPLDKEKLPT------VGSPYWMAPEV 665

Query: 251 HLGKEQSRRDDLEALGHMFMYFLRGSLP 278
             G   + R DL ++G + M  +   +P
Sbjct: 666 LNGHFYNERADLFSVG-IIMCEITARIP 746
>26560
          Length = 398

 Score = 47.4 bits (111), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 37/119 (31%), Positives = 60/119 (50%), Gaps = 1/119 (0%)
 Frame = -1

Query: 163 TFTLKTVLMIAIQLITRMEYVHTKSLIYRDVKPENFLVGRPGSKRQHSIHIIDFGLAKEY 222
            FT K V   A +++  +E++H++ ++YRD+KP N L+   G  R     I D GLA ++
Sbjct: 368 VFTEKEVRFYAAEVMLGLEHMHSRFVVYRDLKPANILLDENGHVR-----ISDLGLACDF 204

Query: 223 IDPETKKHIPYREHKSLTGTARYMSINTHL-GKEQSRRDDLEALGHMFMYFLRGSLPWQ 280
               +KK    R H S+ GT  YM+    + G+      D  + G M    L+G  P++
Sbjct: 203 ----SKK----RPHASV-GTHGYMAPEVLMKGQSYDSSADWFSFGCMLYKLLKGHSPFR 54
>29581
          Length = 1278

 Score = 46.6 bits (109), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 27/83 (32%), Positives = 41/83 (49%)
 Frame = -2

Query: 144  MVLELLGPSLEDLFDLCDRTFTLKTVLMIAIQLITRMEYVHTKSLIYRDVKPENFLVGRP 203
            +V+E     L  L D     F+   V  I +QL+  + Y+H   +I+RD+K  N L+   
Sbjct: 1118 LVMEYCEQDLASLLDNMPAPFSESQVKCIVLQLLKGLRYLHEAFIIHRDLKVSNLLMTDK 939

Query: 204  GSKRQHSIHIIDFGLAKEYIDPE 226
            G      + I DFGLA+ Y  P+
Sbjct: 938  G-----CVKIADFGLARNYGKPQ 885
>21433
          Length = 590

 Score = 45.8 bits (107), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 32/104 (30%), Positives = 47/104 (45%)
 Frame = +2

Query: 175 QLITRMEYVHTKSLIYRDVKPENFLVGRPGSKRQHSIHIIDFGLAKEYIDPETKKHIPYR 234
           QL + +EY H + +I+RD+KPEN L        +  + I DFG +          H P  
Sbjct: 191 QLSSALEYCHYRKVIHRDIKPENLL-----LGLKGDLKIADFGWS---------VHAPSS 328

Query: 235 EHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLP 278
              ++ GT  Y+      GK      DL +LG +   FL G+ P
Sbjct: 329 RRTTMCGTLDYLPPEMVEGKTHDENVDLWSLGVLCYEFLVGTPP 460
>09606
          Length = 1300

 Score = 45.1 bits (105), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 40/165 (24%), Positives = 71/165 (43%), Gaps = 18/165 (10%)
 Frame = -3

Query: 144 MVLELL-GPSLEDLFDLCDRTFTLKTVLMIAIQLITRMEYVHTKSLIYRDVKPENFLVGR 202
           +V+EL  G SL D+    D      ++    I L+T + Y+H+  +++ D++P   L+  
Sbjct: 902 LVVELCTGGSLADILAQ-DHHLPETSIRDFGIHLVTGLHYIHSLGILFHDLRPSKVLLDT 726

Query: 203 PGSKRQHSIHIIDFGLAKEYIDPETKKHIPYR-----------------EHKSLTGTARY 245
            G      +   DFGL+K  ++ E  + + ++                 +    +G+  Y
Sbjct: 725 SGV-----LKFADFGLSK--VEGENLEELFFKFAEAGDQWNIQSAEEMMKQVPTSGSPTY 567

Query: 246 MSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKER 290
           M+     G E S   DL ALG +F     G  P+ G   D  K++
Sbjct: 566 MAPEVFQGAEPSIMSDLWALGCVFYEMFSGHPPFLGETYDITKDK 432
>00300
          Length = 2318

 Score = 44.7 bits (104), Expect = 7e-05,   Method: Compositional matrix adjust.
 Identities = 58/256 (22%), Positives = 101/256 (39%), Gaps = 18/256 (7%)
 Frame = -1

Query: 45   NFRV--GKKIGCGNFGELRLGKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLSTTGEA 102
            NFR   G KIG G FG++    N+ T E +A+K             E +F          
Sbjct: 1661 NFRWQRGNKIGEGQFGKVYTAVNMSTGELMALK-------------EMKFQ--------- 1548

Query: 103  DSGTGPALLGQQWLRTPSMDVSFAEGVPQ---VYYFGPCGKYNAMVLELLGPSLEDLFDL 159
                 P  L Q  LR    ++   EG+     V Y+G     + M++           + 
Sbjct: 1547 -----PNDLQQ--LREMCDEIKIFEGIQHENLVKYYGVEVHKDEMLM---------FMEY 1416

Query: 160  CDRTFTLKTVLMIAI----------QLITRMEYVHTKSLIYRDVKPENFLVGRPGSKRQH 209
            CD T T++    + +          +++  + ++H  S+++RD+K  N  +   G     
Sbjct: 1415 CD-TGTIEEAAKMGLPEYLIRRYTREIVLAVNHLHENSIVHRDIKGANIFLTSNG----- 1254

Query: 210  SIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQ---SRRDDLEALG 266
             + + DFG +   +  ++   +P   H +L GT  YM+       +Q    R  D+ +LG
Sbjct: 1253 HVKLGDFGCS---VKLKSHTTMPGEFH-NLVGTTAYMAPEVFTQNDQGGYGRAADIWSLG 1086

Query: 267  HMFMYFLRGSLPWQGL 282
             + +    G  PW  L
Sbjct: 1085 CVVIEMATGKRPWHDL 1038
>01106
          Length = 878

 Score = 43.9 bits (102), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 43/160 (26%), Positives = 72/160 (45%), Gaps = 5/160 (3%)
 Frame = +3

Query: 46  FRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLSTTGEADSG 105
           + V +K+G G+F  + L  +L    +VA+K+  +KS            K L    E+D  
Sbjct: 324 YHVIRKLGWGHFSTVWLCWDLTCKRFVALKV--VKSAQHYTETALDEVKLLKCVRESDVA 497

Query: 106 TGPALLGQQWLRTPSMDVSFAEGVPQVYYF---GPCGKYNAMVLELLGPSLEDLFDLCD- 161
                           D + A+ V  +  F   G  G + AMV E+LG +L  L    + 
Sbjct: 498 ----------------DPARAKCVQLLDDFKISGVNGTHVAMVFEVLGYNLLKLIIRSNY 629

Query: 162 RTFTLKTVLMIAIQLITRMEYVHTKS-LIYRDVKPENFLV 200
           +   +  V +I  Q++  + Y+H K  +I+ D+KPEN L+
Sbjct: 630 QGIPIHNVKLIIRQVLEGLSYMHAKCRIIHTDIKPENILI 749
>14126
          Length = 1265

 Score = 43.9 bits (102), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 34/128 (26%), Positives = 62/128 (48%), Gaps = 4/128 (3%)
 Frame = +3

Query: 172 IAIQLITRMEYVHTKSLIYRDVKPENFLVGRPGSKRQHSIHIIDFGLAKEYIDPETKKHI 231
           + +QL+  ++++H+  +++RD+KP+N L+ + G      + + DFGLA+           
Sbjct: 531 LMLQLLNGVDFLHSNRIVHRDLKPQNLLISKDG-----RLKLADFGLAR----------- 662

Query: 232 PYREHKSLTG---TARYMSINTHLGKEQSRRDDLEALGHMFM-YFLRGSLPWQGLKADTL 287
            Y  H +LT    T  Y S    +  E     D+ + G +F   F R +L     + D L
Sbjct: 663 IYSFHMALTTVVVTLWYRSPEVLMQAEYGTSVDIWSCGCIFAELFTRRALFKGSSEFDQL 842

Query: 288 KERYQKIG 295
           K+ ++ IG
Sbjct: 843 KKIFEVIG 866
>01060
          Length = 1800

 Score = 43.9 bits (102), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 23/78 (29%), Positives = 42/78 (53%), Gaps = 5/78 (6%)
 Frame = +1

Query: 173 AIQLITRMEYVHTKSLIYRDVKPENFLVGRPGSKRQHSIHIIDFGLAKEYIDP-ETKKH- 230
             Q++T + + H + +++RD+KP+N L+   G     +I I DFG+A+ +  P     H 
Sbjct: 394 VFQIVTGIXFCHQRRIVHRDLKPQNLLINHTG-----AIKIADFGMARTFALPVRAYTHE 558

Query: 231 ---IPYREHKSLTGTARY 245
              + YR  + L G ++Y
Sbjct: 559 VVTLWYRAPEILMGASKY 612
>26711
          Length = 405

 Score = 43.9 bits (102), Expect = 1e-04,   Method: Composition-based stats.
 Identities = 32/119 (26%), Positives = 57/119 (47%)
 Frame = -2

Query: 175 QLITRMEYVHTKSLIYRDVKPENFLVGRPGSKRQHSIHIIDFGLAKEYIDPETKKHIPYR 234
           Q++  +++VH + +++ D+KP N L+      +  S+ +IDFGLA++   P+      + 
Sbjct: 392 QVLDILQHVHAQGVVHMDLKPSNLLL---SGDKLDSVQLIDFGLARKLYPPQET----FL 234

Query: 235 EHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQK 293
            H    GT  + S      K  S   D+  +G +    L G  P+Q   AD+  E  +K
Sbjct: 233 NH----GTPGFTSPEALDVKPISTASDVWGVGVLAYILLSGQSPFQ---ADSATESLKK 78
>21079
          Length = 878

 Score = 43.9 bits (102), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 38/139 (27%), Positives = 65/139 (46%), Gaps = 3/139 (2%)
 Frame = +1

Query: 143 AMVLELLGPSLEDLFDLC---DRTFTLKTVLMIAIQLITRMEYVHTKSLIYRDVKPENFL 199
            +V+E +G    +LF+     D   T +  +    Q+ + + Y+HT+S+++ D+KPEN L
Sbjct: 52  VLVMEFVGAG--ELFERVIRDDFVLTERDCVHFVRQICSGVGYMHTQSILHLDLKPENVL 225

Query: 200 VGRPGSKRQHSIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRR 259
                S   + I IIDFGLA+ Y         P    + L GT  +++       E +  
Sbjct: 226 C---VSDNSNQIKIIDFGLARFY--------KPGDSLQVLFGTPEFIAPEVVNYDEINFT 372

Query: 260 DDLEALGHMFMYFLRGSLP 278
            D+ ++G +    L G  P
Sbjct: 373 TDMWSIGVICYILLSGLSP 429
>04591
          Length = 1117

 Score = 43.5 bits (101), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 25/91 (27%), Positives = 46/91 (50%), Gaps = 3/91 (3%)
 Frame = -2

Query: 136 GPCGKYNA---MVLELLGPSLEDLFDLCDRTFTLKTVLMIAIQLITRMEYVHTKSLIYRD 192
           GP  +Y +   ++ E     L  L +     F+L     +  QL+  + Y+HTK +++RD
Sbjct: 999 GPYNRYKSTFYLIFEYCDYDLAGLLNNLRVKFSLADKKNLMSQLLNGLFYIHTKQILHRD 820

Query: 193 VKPENFLVGRPGSKRQHSIHIIDFGLAKEYI 223
           +K  N L+ R G      + + DFGL++ ++
Sbjct: 819 IKAANILLTRDG-----VLKLADFGLSRPWV 742
>01707
          Length = 757

 Score = 43.1 bits (100), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 37/139 (26%), Positives = 57/139 (41%), Gaps = 1/139 (0%)
 Frame = +1

Query: 144 MVLELLGPSLEDLFDLCDRTFTLKTVLMIAIQLITRMEYVHTKSLIYRDVKPENFLVGRP 203
           +V + +  +L +  D   R      V  I  Q +  + + H  + I+RDVKPEN L+ R 
Sbjct: 292 LVFDYVDHTLLNELDRYPRGLPEPMVKRIIYQTLLAVNFCHQYNTIHRDVKPENILITRQ 471

Query: 204 GSKRQHSIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQ-SRRDDL 262
           G      + + DFG A+    P         E+     T  Y +    +G  Q     D+
Sbjct: 472 G-----QVKLCDFGFARILTGPGD-------EYTDYVATRWYRAPELLVGDTQYGPPVDV 615

Query: 263 EALGHMFMYFLRGSLPWQG 281
            A+G +F   L G   W G
Sbjct: 616 WAIGCVFAELLTGQALWPG 672
>01966
          Length = 1735

 Score = 42.7 bits (99), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 17/53 (32%), Positives = 32/53 (60%)
 Frame = -1

Query: 173  AIQLITRMEYVHTKSLIYRDVKPENFLVGRPGSKRQHSIHIIDFGLAKEYIDP 225
              Q++T + + H + +++RD+KP+N L+   G     +I I DFG+A+ +  P
Sbjct: 1390 VFQIVTGINFCHQRRIVHRDLKPQNLLINHTG-----AIKIADFGMARTFALP 1247
>11780
          Length = 1713

 Score = 42.7 bits (99), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 50/185 (27%), Positives = 73/185 (39%)
 Frame = +3

Query: 36  SSGVLMVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQ 95
           S G ++   +  +G+ IG G+FG++   K +Y  + VAIK    K R  Q      F ++
Sbjct: 573 SGGWVIAXQDLEIGEAIGKGDFGDVY--KGMYRGQPVAIKQLKDKDRGEQ-----SFLQE 731

Query: 96  LSTTGEADSGTGPALLGQQWLRTPSMDVSFAEGVPQVYYFGPCGKYNAMVLELLGPSLED 155
            S            L+G          V   E +  V  F   GK         G  +E 
Sbjct: 732 ASVMTSLRHDNLVRLIG----------VVLGETIFLVTEF--MGK---------GNLVEY 848

Query: 156 LFDLCDRTFTLKTVLMIAIQLITRMEYVHTKSLIYRDVKPENFLVGRPGSKRQHSIHIID 215
           L        T K  +  A      MEY+ +K L++RD+   N LV   G  +     + D
Sbjct: 849 LRSRGRSVITKKDQINFATDTCAAMEYLESKRLVHRDLAARNVLVHDDGKAK-----VSD 1013

Query: 216 FGLAK 220
           FGLAK
Sbjct: 1014FGLAK 1028
>27405
          Length = 532

 Score = 41.6 bits (96), Expect = 6e-04,   Method: Compositional matrix adjust.
 Identities = 29/85 (34%), Positives = 47/85 (55%)
 Frame = -3

Query: 163 TFTLKTVLMIAIQLITRMEYVHTKSLIYRDVKPENFLVGRPGSKRQHSIHIIDFGLAKEY 222
            FT K V   A +++  +E++H++ ++YRD+KP N L+   G  R     I D GLA ++
Sbjct: 266 VFTEKEVRFYAAEVMLGLEHMHSRFVVYRDLKPANILLDENGHVR-----ISDLGLACDF 102

Query: 223 IDPETKKHIPYREHKSLTGTARYMS 247
               +KK    + H S+ GT  YM+
Sbjct: 101 ----SKK----KPHASV-GTHGYMA 54
>11185
          Length = 473

 Score = 41.2 bits (95), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 29/122 (23%), Positives = 53/122 (43%), Gaps = 17/122 (13%)
 Frame = +1

Query: 172 IAIQLITRMEYVHTKSLIYRDVKPENFLVGRPGSKRQHSIHIIDFGLAKEYIDPETKKHI 231
             I L+T + Y+H+  +++ D++P   L+   G      +   DFGL+K  ++ E  + +
Sbjct: 16  FGIHLVTGLHYIHSLGILFHDLRPSKVLLDTSGV-----LKFADFGLSK--VEGENLEEL 174

Query: 232 PYREHKS-----------------LTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLR 274
            ++  ++                  +G+  YM+     G E S   DL ALG +F     
Sbjct: 175 FFKFAEAGDQWNIQSAEEMMKQVPTSGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFS 354

Query: 275 GS 276
           GS
Sbjct: 355 GS 360
>18921
          Length = 697

 Score = 40.4 bits (93), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 44/205 (21%), Positives = 86/205 (41%), Gaps = 3/205 (1%)
 Frame = +2

Query: 46  FRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLSTTGEADSG 105
           F +  K+G G++G +    +  T + +AIK  P+ +   ++       K++S   + DS 
Sbjct: 35  FDILGKLGEGSYGSVFKSLHKETGQVLAIKQVPVDTDLQEI------IKEISIMQQCDSK 196

Query: 106 TGPALLGQQWLRTPSMDVSFAEGVPQVYYFGPCGKYNAM--VLELLGP-SLEDLFDLCDR 162
                                     V Y+G   K   +  V+E  G  S+ D+  L ++
Sbjct: 197 Y------------------------IVKYYGSYFKNTDLWIVMEYCGAGSVSDIMRLRNK 304

Query: 163 TFTLKTVLMIAIQLITRMEYVHTKSLIYRDVKPENFLVGRPGSKRQHSIHIIDFGLAKEY 222
           T   + +  I    +  + Y+H++  I+RD+K  N L+   G  +     + DFG+A + 
Sbjct: 305 TLVEREIATILYYTLKGLXYLHSRRKIHRDIKAGNILLNNEGHAK-----LADFGVAGQL 469

Query: 223 IDPETKKHIPYREHKSLTGTARYMS 247
            D   K++       ++ GT  +M+
Sbjct: 470 TDTMAKRN-------TVIGTPYWMA 523
>01756
          Length = 1858

 Score = 40.0 bits (92), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 41/176 (23%), Positives = 70/176 (39%), Gaps = 4/176 (2%)
 Frame = -3

Query: 51   KIGCGNFGELRLGKNLYTNEYVAIK---LEPIKSRAPQLHL-EYRFYKQLSTTGEADSGT 106
            KIG G FGE+   +   T + VA+K   ++  K   P   L E +  + L+     D   
Sbjct: 1721 KIGQGTFGEVFKARCKKTKQVVAMKKVLMDNEKEGFPITALREIKILQLLNHENVVD--- 1551

Query: 107  GPALLGQQWLRTPSMDVSFAEGVPQVYYFGPCGKYNAMVLELLGPSLEDLFDLCDRTFTL 166
                     +   S   + A     ++Y         +V E     L  L       F L
Sbjct: 1550 --------LIEICSTKATSANRYKSMFY---------LVFEFCEHDLAGLLSNMSVVFNL 1422

Query: 167  KTVLMIAIQLITRMEYVHTKSLIYRDVKPENFLVGRPGSKRQHSIHIIDFGLAKEY 222
              +  +  QL+  + Y+H   +++RD+K  N L+ + G      + + DFGLA+ +
Sbjct: 1421 PEIKEVMKQLMNGLYYIHRNKILHRDMKAANILITKQG-----VLKLADFGLARAF 1269
>01392
          Length = 1806

 Score = 39.7 bits (91), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 35/128 (27%), Positives = 58/128 (45%), Gaps = 5/128 (3%)
 Frame = -1

Query: 159  LCDRTFTLKTVLMIAIQLITRMEYVHTKSLIYRDVKPENFLVGRPGSKRQHSIHIIDFGL 218
            LC+R  +L     +   +   ++++H+K + +RD+KPEN L           + I DF L
Sbjct: 1800 LCEREASL-----VVRHIARALDFLHSKGIAHRDLKPENILCEHLDDVV--PVKICDFDL 1642

Query: 219  AKEYIDPETKKHIPYREHKSLTGTARYMS---INTHLGKEQS--RRDDLEALGHMFMYFL 273
            A            P  E  +  G+A YM+   ++  +G   S  +R DL +LG +    L
Sbjct: 1641 ASGISCDGDGTKTP--ELLTPVGSAEYMAPEVVDAWVGDSFSYDKRCDLWSLGIILYIML 1468

Query: 274  RGSLPWQG 281
             G  P+ G
Sbjct: 1467 CGYPPFYG 1444
>26009
          Length = 886

 Score = 39.7 bits (91), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 13/29 (44%), Positives = 24/29 (82%)
 Frame = +3

Query: 175 QLITRMEYVHTKSLIYRDVKPENFLVGRP 203
           QL++ ++++H+K L++RD+KPEN L+  P
Sbjct: 735 QLVSALDFMHSKQLVHRDIKPENVLILTP 821
>03240
          Length = 1683

 Score = 39.3 bits (90), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 18/45 (40%), Positives = 26/45 (57%)
 Frame = -3

Query: 175 QLITRMEYVHTKSLIYRDVKPENFLVGRPGSKRQHSIHIIDFGLA 219
           +L+  +E VH    I+RD+KP+N L+ R G      I + DFGL 
Sbjct: 967 ELVQAIESVHRMGFIHRDIKPDNILIDRNG-----HIKLTDFGLC 848
>31885
          Length = 529

 Score = 38.9 bits (89), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 23/85 (27%), Positives = 40/85 (47%)
 Frame = -2

Query: 163 TFTLKTVLMIAIQLITRMEYVHTKSLIYRDVKPENFLVGRPGSKRQHSIHIIDFGLAKEY 222
           +F    V     QL   ++Y+ ++ +++RD+KP+N L+   G       H+ DF +A + 
Sbjct: 384 SFREDCVKFYLCQLALVLDYLRSQKIVHRDIKPDNILLDEQG-----HCHVTDFNIATQL 220

Query: 223 IDPETKKHIPYREHKSLTGTARYMS 247
            D E           S +GT  YM+
Sbjct: 219 EDDELA--------TSTSGTRPYMA 169
>15910
          Length = 1361

 Score = 38.5 bits (88), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 36/149 (24%), Positives = 67/149 (44%), Gaps = 5/149 (3%)
 Frame = +2

Query: 151 PSLEDLFDLCDRT-----FTLKTVLMIAIQLITRMEYVHTKSLIYRDVKPENFLVGRPGS 205
           P+  + ++L DR      +T K        ++  ++Y+H   +++RD+KPEN L      
Sbjct: 401 PA*GEWWELFDRIVTRGQYTEKDAARAISDILHGVQYIHANGVVHRDLKPENLLY--ECM 574

Query: 206 KRQHSIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEAL 265
                + + DFGL++  I+PE        +  ++ GT  Y +     G + +   D+ ++
Sbjct: 575 TDDSKLKLADFGLSR-IIEPEV-------QMSTVCGTPGYCAPEVLKGDKYTPSVDMWSV 730

Query: 266 GHMFMYFLRGSLPWQGLKADTLKERYQKI 294
           G +    L G  P     A+   E Y+KI
Sbjct: 731 GVIAYILLCGYEP---FFAENEFEMYRKI 808
>03508
          Length = 1463

 Score = 38.5 bits (88), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 18/61 (29%), Positives = 35/61 (57%)
 Frame = +1

Query: 162 RTFTLKTVLMIAIQLITRMEYVHTKSLIYRDVKPENFLVGRPGSKRQHSIHIIDFGLAKE 221
           +TFT   +     +L+  +++ H+  +++RDVKP N ++     K    + +ID+GLA+ 
Sbjct: 856 QTFTDYDIRFYLYELMKALDFCHSMGIMHRDVKPHNVMIDHENKK----LRLIDWGLAEF 1023

Query: 222 Y 222
           Y
Sbjct: 1024Y 1026
>00715
          Length = 1788

 Score = 38.1 bits (87), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 39/177 (22%), Positives = 71/177 (40%), Gaps = 18/177 (10%)
 Frame = +1

Query: 144 MVLELLGP-SLEDLFDLCDRTFTLKTVLMIAIQLITRMEYVHTKSLIYRDVKPENFLVGR 202
           + +E +GP +L+ + +   +       L +A+Q+   + Y+H+ ++++ D+KP N L+  
Sbjct: 166 LAMEYVGPLNLQTILNDHQQDIDSSMRLSLALQMARGLHYLHSINIVHLDLKPANCLL-- 339

Query: 203 PGSKRQHSIHIIDFGLAKEYIDPETKKHIPYRE-----------------HKSLTGTARY 245
               R   + I DFG   +     T   +  RE                    L GT  Y
Sbjct: 340 ---TRDLKLRIADFGCCHQLT--PTGLDMGEREGGMAGNELELTPVQGAWKNELAGTLAY 504

Query: 246 MSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATP 302
            +     G + S R D+ +LG           P++G+ A  +   YQ +    R  P
Sbjct: 505 RAPELLKGLQPSVRSDVYSLGITLWQMCTRQGPYEGVPAHAVV--YQVVSKDLRPCP 669
>19094
          Length = 898

 Score = 37.7 bits (86), Expect = 0.009,   Method: Compositional matrix adjust.
 Identities = 23/96 (23%), Positives = 47/96 (48%)
 Frame = +1

Query: 152 SLEDLFDLCDRTFTLKTVLMIAIQLITRMEYVHTKSLIYRDVKPENFLVGRPGSKRQHSI 211
           S+ D+  L ++T   + +  I    +  + Y+H++  I+RD+K  N L+   G  +    
Sbjct: 13  SVSDIMRLRNKTLVEREIATILYYTLKGL*YLHSRRKIHRDIKAGNILLNNEGHAK---- 180

Query: 212 HIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMS 247
            + DFG+A +  D   K++       ++ GT  +M+
Sbjct: 181 -LADFGVAGQLTDTMAKRN-------TVIGTPYWMA 264
>04852
          Length = 1462

 Score = 37.4 bits (85), Expect = 0.012,   Method: Compositional matrix adjust.
 Identities = 31/139 (22%), Positives = 60/139 (43%), Gaps = 3/139 (2%)
 Frame = +1

Query: 167 KTVLMIAIQLITRMEYVHTKSLIYRDVKPENFLVGRPGSKRQHSIHIIDFGLAK--EYID 224
           K +L  A Q+   ME++ ++  I+RD+   N LV       +H + I DFGL++  +Y  
Sbjct: 325 KNLLSYAFQIARGMEFLASRKCIHRDLAARNVLV-----TEEHVLKIADFGLSRTGDYYK 489

Query: 225 PETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALG-HMFMYFLRGSLPWQGLK 283
             +   +P           ++M+         + + D+ + G  ++  F  G +P+  + 
Sbjct: 490 KRSGGRLP----------VKWMAPEALFDMRYTTKSDVWSFGVVLWEIFSLGGMPYASIP 639

Query: 284 ADTLKERYQKIGDTKRATP 302
            + L   Y K+ D     P
Sbjct: 640 NEEL---YSKLLDDAYRMP 687
>16708
          Length = 1397

 Score = 35.8 bits (81), Expect = 0.034,   Method: Compositional matrix adjust.
 Identities = 17/54 (31%), Positives = 31/54 (57%)
 Frame = -1

Query: 169  VLMIAIQLITRMEYVHTKSLIYRDVKPENFLVGRPGSKRQHSIHIIDFGLAKEY 222
            V  IA Q +  +E++H   +++ DVK +N LV   G+ +     + D+G+A+ Y
Sbjct: 1088 VCCIAGQXVCALEHIHELGVVHMDVKADNVLVDAHGNCK-----LTDYGIAQLY 942
>19761
          Length = 473

 Score = 35.8 bits (81), Expect = 0.040,   Method: Compositional matrix adjust.
 Identities = 26/105 (24%), Positives = 49/105 (46%), Gaps = 2/105 (1%)
 Frame = -3

Query: 167 KTVLMIAIQLITRMEYVHTKS--LIYRDVKPENFLVGRPGSKRQHSIHIIDFGLAKEYID 224
           + ++   +Q  + + Y+HT +  +++RD+KP+N  V   G  R     + D GLA++   
Sbjct: 423 RLIVCWLMQTASALNYMHTHTPVILHRDLKPQNIYVTEKGDVR-----LGDLGLARKLTG 259

Query: 225 PETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMF 269
           P            S  GT  Y+S      +  + + D+ +LG +F
Sbjct: 258 PADFA-------TSQVGTIMYLSPEILSQQPYNSKSDIWSLGCVF 145
>07940
          Length = 1336

 Score = 35.0 bits (79), Expect = 0.057,   Method: Compositional matrix adjust.
 Identities = 19/59 (32%), Positives = 31/59 (52%)
 Frame = -3

Query: 162 RTFTLKTVLMIAIQLITRMEYVHTKSLIYRDVKPENFLVGRPGSKRQHSIHIIDFGLAK 220
           +  T K ++  A Q+   MEY+ +K  I+RD+   N LV       ++ + I DFGL +
Sbjct: 362 KMLTPKDLISYAYQVARGMEYLASKQCIHRDLAARNVLVA-----EEYVLKIADFGLTR 201
>21800
          Length = 855

 Score = 34.7 bits (78), Expect = 0.077,   Method: Compositional matrix adjust.
 Identities = 22/67 (32%), Positives = 38/67 (56%), Gaps = 2/67 (2%)
 Frame = +2

Query: 136 GPCGKYNAMVLELLGPSLEDLFDLCD-RTFTLKTVLMIAIQLITRMEYVHTK-SLIYRDV 193
           G  G +  MV E+LG +L  L    + +   +  V +I  Q++  + Y+H K ++I+ D+
Sbjct: 536 GVNGTHVCMVFEVLGYNLLKLIIRSNYQGIPVHNVKLIIRQVLEGLNYLHAKCNIIHTDI 715

Query: 194 KPENFLV 200
           KPEN L+
Sbjct: 716 KPENILI 736
>28157
          Length = 400

 Score = 34.7 bits (78), Expect = 0.087,   Method: Composition-based stats.
 Identities = 20/49 (40%), Positives = 30/49 (61%), Gaps = 3/49 (6%)
 Frame = +3

Query: 174 IQLITRMEYVH---TKSLIYRDVKPENFLVGRPGSKRQHSIHIIDFGLA 219
           +Q    +EY+H    K+LI+RD+KP N L+ + G+K    + I DFG A
Sbjct: 237 LQCALGVEYLHGMKPKALIHRDLKPPNLLLIQCGTK----LKICDFGTA 371
>04138
          Length = 800

 Score = 34.3 bits (77), Expect = 0.092,   Method: Compositional matrix adjust.
 Identities = 14/44 (31%), Positives = 26/44 (59%)
 Frame = +1

Query: 179 RMEYVHTKSLIYRDVKPENFLVGRPGSKRQHSIHIIDFGLAKEY 222
           R+ Y+H   +++RD+K  N L+ + G      + + DFGLA+ +
Sbjct: 49  RLYYIHRNKILHRDMKAANILITKQG-----VLKLADFGLARAF 165
>13066
          Length = 551

 Score = 34.3 bits (77), Expect = 0.11,   Method: Compositional matrix adjust.
 Identities = 19/73 (26%), Positives = 37/73 (50%)
 Frame = +3

Query: 175 QLITRMEYVHTKSLIYRDVKPENFLVGRPGSKRQHSIHIIDFGLAKEYIDPETKKHIPYR 234
           Q+ T + Y+H+  + +RD+K EN L+         ++ + DFG A   I    +K++   
Sbjct: 300 QMTTALNYLHSYDVAHRDLKCENILLS-----SHFNVKLADFGFACACITESGEKYMS-- 458

Query: 235 EHKSLTGTARYMS 247
             ++  G+A Y +
Sbjct: 459 --RTYCGSAAYAA 491
>27546
          Length = 426

 Score = 33.5 bits (75), Expect = 0.20,   Method: Composition-based stats.
 Identities = 17/46 (36%), Positives = 29/46 (63%)
 Frame = -1

Query: 175 QLITRMEYVHTKSLIYRDVKPENFLVGRPGSKRQHSIHIIDFGLAK 220
           Q+   ++Y+H+  + +RD+K EN L+    SKR  ++ I DFG A+
Sbjct: 156 QMAKALQYLHSHDIAHRDLKCENILL----SKRL-NVKIADFGFAR 34
>12786
          Length = 460

 Score = 32.7 bits (73), Expect = 0.28,   Method: Compositional matrix adjust.
 Identities = 24/94 (25%), Positives = 44/94 (46%), Gaps = 1/94 (1%)
 Frame = -3

Query: 175 QLITRMEYVHTKSLIYRDVKPENFLVGRPGSKRQHSIHIIDFGLAKEYIDPETKKHIPYR 234
           +++  ++ +H + +I+ D+KP NF++         ++ +IDFG+A      +T      R
Sbjct: 386 EMLRAVKALHNEGVIHSDLKPANFML------VAGNLKLIDFGIANTLQQDKTSVLKDSR 225

Query: 235 EHKSLTGTARYMSINTHLGK-EQSRRDDLEALGH 267
                 GT  YMS    +   + S  D +E  GH
Sbjct: 224 -----VGTPSYMSPEAIMAACDDSADDSMEEDGH 138
>14477
          Length = 493

 Score = 32.3 bits (72), Expect = 0.39,   Method: Compositional matrix adjust.
 Identities = 38/173 (21%), Positives = 68/173 (39%), Gaps = 3/173 (1%)
 Frame = -1

Query: 51  KIGCGNFGELRLGKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLSTTGEADSGTGPAL 110
           K+G GNFG +  G     +  + + ++ +K+      ++    K+     + D       
Sbjct: 469 KLGAGNFGSVMKGVCRLDDREIPVAIKVLKNADLDPSVQSELIKEAEVMKKMDH------ 308

Query: 111 LGQQWLRTPSMDVSFAEGVPQVYYFGPC-GKYNAMVLEL--LGPSLEDLFDLCDRTFTLK 167
                             +  V   G C G+   +VLEL  LGP   + F   ++   L 
Sbjct: 307 ------------------MHIVRLIGLCEGETMMLVLELAKLGPL--NKFLPKNKHLPLW 188

Query: 168 TVLMIAIQLITRMEYVHTKSLIYRDVKPENFLVGRPGSKRQHSIHIIDFGLAK 220
            +L +  Q+   MEY+     ++RD+   N L+       +H   I DFG++K
Sbjct: 187 NILELMWQVSQGMEYLEANKFVHRDLAARNILLC-----DEHFAKISDFGMSK 44
>19301
          Length = 712

 Score = 32.3 bits (72), Expect = 0.40,   Method: Compositional matrix adjust.
 Identities = 17/49 (34%), Positives = 27/49 (55%)
 Frame = +2

Query: 169 VLMIAIQLITRMEYVHTKSLIYRDVKPENFLVGRPGSKRQHSIHIIDFG 217
           VL  + Q+ + M Y+H+  +I+RD+K  N LV      +   + I DFG
Sbjct: 575 VLDWSKQIASGMNYLHSHKIIHRDLKSPNVLVA-----KNDVVKISDFG 706
>14116
          Length = 1017

 Score = 32.0 bits (71), Expect = 0.49,   Method: Compositional matrix adjust.
 Identities = 19/70 (27%), Positives = 33/70 (47%), Gaps = 5/70 (7%)
 Frame = -1

Query: 165 TLKTVLMIAIQLITRMEYVHTKSLIYRDVKPENFLVGRPGSKRQHSIHIIDFGLA----- 219
           T+K ++M  + +   M+Y+     ++RD+   N ++          + + DFGLA     
Sbjct: 327 TIKDLIMYGVDIARGMDYLAGLKFVHRDLAARNCML-----DEDFHVKVADFGLARDIYE 163

Query: 220 KEYIDPETKK 229
           KEY   E KK
Sbjct: 162 KEYYSSENKK 133
>31489
          Length = 329

 Score = 31.6 bits (70), Expect = 0.60,   Method: Composition-based stats.
 Identities = 11/39 (28%), Positives = 25/39 (64%)
 Frame = +3

Query: 161 DRTFTLKTVLMIAIQLITRMEYVHTKSLIYRDVKPENFL 199
           D+  T + +     Q++  ++Y+H+ ++++RD+KP N L
Sbjct: 147 DQPLTEEHIRYFLYQILRGLKYIHSANVVHRDLKPSNLL 263
>17975
          Length = 449

 Score = 29.3 bits (64), Expect = 3.2,   Method: Compositional matrix adjust.
 Identities = 14/46 (30%), Positives = 26/46 (56%), Gaps = 1/46 (2%)
 Frame = +3

Query: 175 QLITRMEYVHTKSLIYRDVKPENFL-VGRPGSKRQHSIHIIDFGLA 219
           Q++  + Y H   +++RD+KPEN +   +PG      + + DFG +
Sbjct: 291 QIVEAISYCHKLHVVHRDLKPENVVFFEKPG-----LVKLTDFGFS 413
>32359
          Length = 928

 Score = 28.1 bits (61), Expect = 7.0,   Method: Compositional matrix adjust.
 Identities = 22/62 (35%), Positives = 30/62 (48%), Gaps = 6/62 (9%)
 Frame = -1

Query: 20  KTGTSRSNHGVRSSGTSSGVLMVGPN------FRVGKKIGCGNFGELRLGKNLYTNEYVA 73
           K G  +S+HG   SG        GP+      +   K IG G+FG +   K + T+E VA
Sbjct: 499 KQGWGQSDHGTGHSGQ-------GPDRPQEVSYTDAKVIGNGSFGVVYQAKLVDTSELVA 341

Query: 74  IK 75
           IK
Sbjct: 340 IK 335
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31542795|ref|NP_034303.2| fatty acid amide hydrolase
[Mus musculus]
         (579 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

20142                                                                 127   9e-30
09083                                                                  41   0.001
15574                                                                  29   4.1  
20319                                                                  28   7.1  
>20142
          Length = 854

 Score =  127 bits (320), Expect = 9e-30,   Method: Compositional matrix adjust.
 Identities = 89/274 (32%), Positives = 132/274 (48%), Gaps = 6/274 (2%)
 Frame = -2

Query: 302 LFRLDSTIPPLPFREEIYRSSRPLRVGYYETDNYTMPTPAMRRAVMETKQSLEAAGHTLV 361
           +  LD ++PP+PF E+   S+R L++GYY  D    P PA+RRAV E   +LE  GHT+V
Sbjct: 838 MLELDPSLPPIPFHEKDLTSTRKLKIGYYSWDGCVPPVPAVRRAVKEATAALEKLGHTVV 659

Query: 362 PFLPNNIPYA-LEVLSAGGLFSDGGCSFLQNFKGDFVDPCLGDLVLVLKLPRWXXXXXXX 420
            F P+ +     + L    + +D G +     K D+ D  L  +VL+ +LPRW       
Sbjct: 658 EFXPDLLYEGYYKYLGYTMIGADQGMTLRTAVKDDYKDVGL-RIVLLNRLPRWXFSLLAR 482

Query: 421 XXXXXXXXXAAFL-NSMCPRSAEKLWELQHEIEMYRQSVIAQWKAMNLDVVLTPMLG-PA 478
                    +  + ++     A   ++   ++  YR     +WK   LD V+ P+   PA
Sbjct: 481 IIHFKEPLVSKIMQHTDSDGRAYSFFQRSKKLLDYRVRFTKEWKNQGLDAVICPVFPCPA 302

Query: 479 LDLNAPGRATGAISYTVLYNCLDFPAGXXXXXXXXAEDDAQMEHYKGY-FGDMWDNXXXX 537
                 G  T A SY  LYN L++PAG         +D A + + + Y    + +     
Sbjct: 301 PKTAHVGNLTAAGSYCGLYNVLNYPAGVVPVTKVTRQDVADVCNPQLYPHSTLLETLVKK 122

Query: 538 X--XXXXXXXPVAVQCVALPWQEELCLRFMREVE 569
                     PVAVQCV LP++EELCLR MRE+E
Sbjct: 121 SCDKEQSVGLPVAVQCVTLPYKEELCLRVMRELE 20
>09083
          Length = 1479

 Score = 40.8 bits (94), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 37/127 (29%), Positives = 57/127 (44%), Gaps = 3/127 (2%)
 Frame = +2

Query: 237 DIGGSIRFPSAFCGICGLKPTGNRLSKSGLKSCVYGQTAVQLSVGPMARDVDSLALCMKA 296
           D GGSIR P++F GI GLKPT   +  +G  +     T   L  GPM + V   AL ++ 
Sbjct: 269 DQGGSIRIPASFTGIVGLKPTWGLVPYTGAHNI--DPTVDHL--GPMTKTVADCALLLEV 436

Query: 297 LLCEDLFRLDSTIPPLP---FREEIYRSSRPLRVGYYETDNYTMPTPAMRRAVMETKQSL 353
           +   D  R    +P L    + + I +     +VG    + + + T  +   V +    L
Sbjct: 437 IAGYDDGRDPRQLPSLSVPDYSKLIEQDVSGKKVGLL-VEGFEVSTXEVSTVVKDAANKL 613

Query: 354 EAAGHTL 360
             AG +L
Sbjct: 614 TQAGCSL 634
>15574
          Length = 1382

 Score = 29.3 bits (64), Expect = 4.1,   Method: Compositional matrix adjust.
 Identities = 12/30 (40%), Positives = 18/30 (60%)
 Frame = +1

Query: 249 CGICGLKPTGNRLSKSGLKSCVYGQTAVQL 278
           C +CG KPTG  +     K+ +Y +T +QL
Sbjct: 709 CSLCGFKPTGQVIDNQ--KTHIYSETYIQL 792
>20319
          Length = 1200

 Score = 28.5 bits (62), Expect = 7.1,   Method: Compositional matrix adjust.
 Identities = 15/47 (31%), Positives = 22/47 (46%)
 Frame = -2

Query: 122 ETQLSQAPRQGLLYGVPVSLKECFSYKGHASTLGLSLNEGVTSESDC 168
           E   + +P Q  L G  V++   FS+  H S L LSL   + +   C
Sbjct: 359 ERSSAASP*QACLSGADVAVSSAFSFSCHDSKLTLSLTNSLQTSRRC 219
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|19526463|ref|NP_080405.1| endoplasmic reticulum
protein ERp29 precursor [Mus musculus]
         (262 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

13375                                                                 125   1e-29
03108                                                                  50   1e-06
12181                                                                  29   2.3  
>13375
          Length = 1075

 Score =  125 bits (315), Expect = 1e-29,   Method: Compositional matrix adjust.
 Identities = 68/160 (42%), Positives = 106/160 (66%), Gaps = 2/160 (1%)
 Frame = +2

Query: 30  HGGSGLHTKGALPLDTVTFYKVIPKSKFVLVKFDTQYPYGEKQDEFKRLAENSASSEELL 89
           H G G   KG++ L++  F KVI K K VLVKFD  YPYG+KQD FK++A  + +  +LL
Sbjct: 584 HAG-GEIVKGSVNLNSGVFDKVIEKHKAVLVKFDETYPYGDKQDNFKKVAAAAITQPDLL 760

Query: 90  VAEVGISDYGDKLNMELSEKYKLDKESYPVFYLFRDGDLENPVLYNG-AVKVGAIQRW-L 147
           VAEV I+DYGDK N +L+E++++ KE +PV+ LF  G  ++PV + G A     ++++ +
Sbjct: 761 VAEVQIADYGDKDNADLAERFQVKKEDFPVYKLFLQG-TKDPVPFTGDATNADKVKKFIM 937

Query: 148 KGQGVYLGMPGCLPAYDALAGEFIKASSIEARQAILKQGQ 187
           +  G++LG+P CL  +D L  EF KA   + R+ +L++ +
Sbjct: 938 ENSGLWLGLPACLEEFDKLVSEFFKAKG-DDRKXVLQRAE 1054
>03108
          Length = 2077

 Score = 49.7 bits (117), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 24/43 (55%), Positives = 34/43 (79%)
 Frame = -1

Query: 210  KILDQGEDFPASEMARIGKLIENKMSDSKKEELQKSLNILTAF 252
            KILD+G++F  +E+ R+ KL + K+SD KKE+L K LNILT+F
Sbjct: 2044 KILDKGDEFVNTEIERVEKLKDGKVSDKKKEQLGKRLNILTSF 1916
>12181
          Length = 422

 Score = 28.9 bits (63), Expect = 2.3,   Method: Compositional matrix adjust.
 Identities = 13/34 (38%), Positives = 23/34 (67%), Gaps = 2/34 (5%)
 Frame = -3

Query: 96  SDYGDKLNMELSEKYKLD--KESYPVFYLFRDGD 127
           +D  D +N+    K +L+  K+S+P+FYL R+G+
Sbjct: 141 TDRHDTINLSFL*KRRLNNIKKSHPIFYLSREGN 40
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6755594|ref|NP_035561.1| elongation factor Tu GTP
binding domain containing 2 isoform a [Mus musculus]
         (971 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

20758                                                                  76   1e-29
15617                                                                  92   1e-18
26111                                                                  70   1e-15
08198                                                                  73   7e-13
05177                                                                  43   7e-04
13945                                                                  41   0.002
32306                                                                  35   0.20 
16090                                                                  34   0.34 
35083                                                                  30   4.7  
>20758
          Length = 530

 Score = 75.9 bits (185), Expect(2) = 1e-29,   Method: Compositional matrix adjust.
 Identities = 44/117 (37%), Positives = 58/117 (49%), Gaps = 1/117 (0%)
 Frame = +2

Query: 838 PADCVSAVYTVLARRRGHVTQDAPIPGSPLYTIKAFIPAIDSFGFETDLRTHTQGQAFSL 897
           P D +  +Y  L +RRG V  + P+PG+PL   KA++P  +SFGF   LR  T G+AF  
Sbjct: 188 PDDAMGGIYQTLTQRRGIVIGEEPVPGTPLVICKAYLPVAESFGFTQHLRQSTSGRAFPQ 367

Query: 898 SVFHHWQIVPGDPLDKSIVIRPLEPQPAPHLAREFMIKTRRRKGLSEDV-SISKFFD 953
            VF HW          +I   PLE     H   E +   R+RKGL   V  +  F D
Sbjct: 368 CVFDHW---------DTINTSPLEEGTKGHSVCEGI---RKRKGLKPGVPGLDNFLD 502

 Score = 73.6 bits (179), Expect(2) = 1e-29,   Method: Composition-based stats.
 Identities = 32/63 (50%), Positives = 42/63 (66%)
 Frame = +3

Query: 776 GPLCDELIRNVKFKILDAVVAQEPLHRGGGQIIPTARRVVYSAFLMATPRLMEPYYFVEV 835
           G + +E +R +KF I D  +  + +HRGGGQIIPTARRV Y+A L A PR  EP +  E+
Sbjct: 3   GVMTEENMRGIKFNIQDVSLHTDAIHRGGGQIIPTARRVFYAACLSAEPRFQEPVFLCEI 182

Query: 836 QAP 838
           Q P
Sbjct: 183 QTP 191
>15617
          Length = 595

 Score = 91.7 bits (226), Expect = 1e-18,   Method: Compositional matrix adjust.
 Identities = 48/145 (33%), Positives = 81/145 (55%), Gaps = 13/145 (8%)
 Frame = -3

Query: 128 IRNVTLCGHLHHGKTCFVDCLIEQTHPEIRKRYDQDLCYTDILFTEQERGVGIKSTPVTV 187
           IRN+++  H+ HGK+   D L+ +    I      +  +TD    EQER + IKST +++
Sbjct: 434 IRNMSVIAHVDHGKSTLTDSLVSKAGI-IASAKAGETRFTDTRKDEQERCITIKSTAISL 258

Query: 188 VLP-------------DTKGKSYLFNIMDTPGHVNFSDEVTAGLRISDGVVLFIDAAEGV 234
                           D    ++L N++D+PGHV+FS EVTA LR++DG ++ +D   GV
Sbjct: 257 YYELKKDDMKYIKQDYDQDNNAFLINLIDSPGHVDFSSEVTAALRVTDGALVVVDCVSGV 78

Query: 235 MLNTERLIKHAVQERLAVTVCINKI 259
            + TE +++ A+ ER+   + +NK+
Sbjct: 77  CVQTETVLRQAIGERIRPVLMMNKM 3
>26111
          Length = 413

 Score = 70.1 bits (170), Expect(2) = 1e-15,   Method: Composition-based stats.
 Identities = 31/81 (38%), Positives = 48/81 (59%)
 Frame = -3

Query: 693 KGLAEDIENEVVQITWNRKKLGEFFQTKYDWDLLAARSIWAFGPDATGPNILVDDTLPSE 752
           +GLAE I+   +  T N K+ G+     +++DL  A  IW FGP+ +GPN+LVD T   +
Sbjct: 231 RGLAEAIDEGTIAATQNVKERGKMLNASFNFDLNLAHKIWCFGPEGSGPNLLVDSTFAVQ 52

Query: 753 VDKALLGSVKDSIVQGFQWGT 773
                L  ++D++V GFQW +
Sbjct: 51  ----HLQDIRDTVVAGFQWAS 1

 Score = 31.6 bits (70), Expect(2) = 1e-15,   Method: Composition-based stats.
 Identities = 14/24 (58%), Positives = 16/24 (66%)
 Frame = -1

Query: 652 IKVADPVVTFCETVVETSSLKCFA 675
           IK +DPVV +CETV   SS  C A
Sbjct: 356 IKKSDPVVRYCETVTAPSSQVCLA 285
>08198
          Length = 2555

 Score = 72.8 bits (177), Expect = 7e-13,   Method: Compositional matrix adjust.
 Identities = 41/131 (31%), Positives = 63/131 (48%), Gaps = 4/131 (3%)
 Frame = -1

Query: 825  RLMEPYYFVEVQAPADCVSAVYTVLARRRGHVTQDAPIPGSPLYTIKAFIPAIDSFGFET 884
            RLM   Y   +QA  D +  +Y V+ +R G V Q+    G+ ++ +    P  +SFG   
Sbjct: 2171 RLMVAMYRCVIQADMDILGKLYAVIGKRNGRVIQEQLREGTQIFNVVTEFPVAESFGLAE 1992

Query: 885  DLRTHTQGQAFSLSVFHHWQIVPGDPL----DKSIVIRPLEPQPAPHLAREFMIKTRRRK 940
            ++R  T G A     F HWQ++  DP      +   +   E   + + AR +M + RRRK
Sbjct: 1991 EMRKRTSGLASPQLRFSHWQVLDIDPFWVPSTEEEYLHYGEKADSDNQARTYMNEVRRRK 1812

Query: 941  GLSEDVSISKF 951
            GL  D  I +F
Sbjct: 1811 GLKVDEKIVEF 1779
>05177
          Length = 594

 Score = 42.7 bits (99), Expect = 7e-04,   Method: Composition-based stats.
 Identities = 31/110 (28%), Positives = 53/110 (48%)
 Frame = -3

Query: 811 ARRVVYSAFLMATPRLMEPYYFVEVQAPADCVSAVYTVLARRRGHVTQDAPIPGSPLYTI 870
           A + +  A   A P+L+EP   +E+    D +  V   L++RR HV  +       +  +
Sbjct: 565 AVQCLTQAIKQAGPQLLEPLMKLEISTDEDKLHGVLGDLSQRRSHV--NFITSRHDIKLV 392

Query: 871 KAFIPAIDSFGFETDLRTHTQGQAFSLSVFHHWQIVPGDPLDKSIVIRPL 920
           +A  P  +  G+ TDLRT T G A       H+Q  P + + ++ VI+ +
Sbjct: 391 EALTPLSELVGYSTDLRTITSGTATVSMELSHYQ--PMNVIQQNHVIQSI 248
>13945
          Length = 664

 Score = 40.8 bits (94), Expect = 0.002,   Method: Composition-based stats.
 Identities = 19/42 (45%), Positives = 24/42 (57%)
 Frame = -3

Query: 463 AMSDCDPDGPLMCHTTKMYSTDDGVQFHAFGRVLSGTIHAGQ 504
            +  CDP G L+ + +KM  T D  +F AFGRV SG  H G 
Sbjct: 614 GIKTCDPKGELVMYVSKMVPTSDKGRFFAFGRVFSG--HCGH 495
>32306
          Length = 441

 Score = 34.7 bits (78), Expect = 0.20,   Method: Compositional matrix adjust.
 Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 2/110 (1%)
 Frame = +1

Query: 633 ELYLDCVMHDLRKMYSEIDIKVADPVVTFCETVVETSSLKCFAETPNKKNKITMIAEPLE 692
           E++L   + DL + Y+ I++ V+ P+V F ETV+    +    E    +N  T++A    
Sbjct: 7   EVHLQRCIDDLTQRYANIEVNVSKPIVPFRETVIPRPKVDRVNEAIQDQN--TVLASARL 180

Query: 693 KGLAEDIE--NEVVQITWNRKKLGEFFQTKYDWDLLAARSIWAFGPDATG 740
           K   +D E  +E +         G F    Y       R+ W+F  +A G
Sbjct: 181 KDFEDDREVXDEGLVSMLTPNTSGWFKSGCY-----PCRARWSFADEAPG 315
>16090
          Length = 468

 Score = 33.9 bits (76), Expect = 0.34,   Method: Composition-based stats.
 Identities = 26/96 (27%), Positives = 46/96 (47%), Gaps = 11/96 (11%)
 Frame = +1

Query: 266 LKLPPTDAYYKLRHIVDEVNGLI-----SMYSTDENLILSPLLGNVCFSSSQYSICFTLG 320
           LKLP T  Y + RH+      L+     S+Y T    I++ +L  + +   + +IC ++ 
Sbjct: 175 LKLPNTHNYAQCRHVEQRKFNLVLNFWWSLYYTHLTTIINSILSMLIY-EQECTICTSIV 351

Query: 321 SFAKIYADTF------GDINYQEFAKRLWGDIYFNP 350
           S A +  +T       G   ++E  +R WG++Y  P
Sbjct: 352 SNALVLYNTLCALYWCGVDVHRECDERGWGNVYNKP 459
>35083
          Length = 568

 Score = 30.0 bits (66), Expect = 4.7,   Method: Composition-based stats.
 Identities = 21/67 (31%), Positives = 35/67 (52%)
 Frame = +1

Query: 250 LAVTVCINKIDRLILELKLPPTDAYYKLRHIVDEVNGLISMYSTDENLILSPLLGNVCFS 309
           L +  C +K   L L++K+  T   +  RHI ++++ LIS  S  E +  S L+  VC  
Sbjct: 358 LMMDTC*DKY*HLNLKMKVNVTTPSFSGRHIFNKIHLLIS*TSKKEMINCSLLMAFVCI- 534

Query: 310 SSQYSIC 316
              +S+C
Sbjct: 535 ---FSLC 546
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31543845|ref|NP_038791.2| transducin (beta)-like 2
[Mus musculus]
         (442 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

27059                                                                 108   2e-29
09883                                                                  59   4e-09
00561                                                                  48   9e-06
02147                                                                  45   7e-05
01249                                                                  44   1e-04
03387                                                                  44   2e-04
02960                                                                  43   2e-04
27465                                                                  43   3e-04
17598                                                                  42   6e-04
30256                                                                  42   6e-04
19498                                                                  41   0.001
13335                                                                  40   0.002
12806                                                                  40   0.002
19949                                                                  39   0.003
30176                                                                  39   0.004
31864                                                                  37   0.018
17602                                                                  37   0.018
02090                                                                  36   0.025
01462                                                                  36   0.030
15337                                                                  36   0.039
15972                                                                  35   0.047
03044                                                                  35   0.062
26107                                                                  35   0.089
11915                                                                  34   0.090
12960                                                                  34   0.091
30297                                                                  34   0.099
19863                                                                  34   0.10 
20271                                                                  33   0.19 
31474                                                                  33   0.19 
25930                                                                  33   0.20 
00825                                                                  33   0.20 
14500                                                                  33   0.24 
15118                                                                  32   0.56 
30295                                                                  32   0.63 
01768                                                                  32   0.65 
31384                                                                  32   0.68 
19140                                                                  32   0.72 
13278                                                                  31   0.78 
26939                                                                  31   0.89 
12574                                                                  31   1.1  
37180                                                                  30   1.3  
03395                                                                  30   1.5  
34511                                                                  30   1.9  
07151                                                                  30   2.0  
29912                                                                  30   2.4  
19571                                                                  30   2.6  
17298                                                                  30   2.6  
27525                                                                  29   3.1  
15745                                                                  29   3.9  
14555                                                                  29   4.2  
>27059
          Length = 411

 Score =  108 bits (270), Expect(2) = 2e-29,   Method: Composition-based stats.
 Identities = 57/103 (55%), Positives = 72/103 (69%)
 Frame = +2

Query: 138 VRFSPDCRAFIVWLANGDTLRVFKMTKREDGGFTFTATPEDFPKKHKAPIINIGIADTGK 197
           ++FSPD +A IV L   +TLRV K+ K+E   ++FT T  DFPK   A IINIGIA TG 
Sbjct: 8   IKFSPDDKACIVSLGIENTLRVMKI-KKETNTYSFT-TCADFPKIISAEIINIGIASTGN 181

Query: 198 FIMTASSDTTVLIWNLKGQVLSTINTNQMNNSHAVISPCSRFV 240
           FIMT  S+TT+ IW+LKG++L TI+T  M N   V+SPC RFV
Sbjct: 182 FIMTCHSNTTMAIWSLKGELLQTIDTGNMVNYFGVVSPCGRFV 310

 Score = 38.9 bits (89), Expect(2) = 2e-29,   Method: Compositional matrix adjust.
 Identities = 17/32 (53%), Positives = 22/32 (68%)
 Frame = +3

Query: 242 SCGFTPDVKVWEVCFGKKGEFQEVLRAFELKG 273
           S GF  D +VW V F K   F++V+RA+ELKG
Sbjct: 315 STGFASDARVWFVEFDKSKTFKQVVRAYELKG 410

 Score = 31.6 bits (70), Expect = 0.64,   Method: Composition-based stats.
 Identities = 19/60 (31%), Positives = 31/60 (51%), Gaps = 1/60 (1%)
 Frame = +2

Query: 62  RVRKEKPQQHSFTHPLLAAALKSHSGNISCMDFSSNGKYLATCADDRTVRIWSTK-DFLQ 120
           RV K K + ++++    A   K  S  I  +  +S G ++ TC  + T+ IWS K + LQ
Sbjct: 68  RVMKIKKETNTYSFTTCADFPKIISAEIINIGIASTGNFIMTCHSNTTMAIWSLKGELLQ 247
>09883
          Length = 650

 Score = 58.9 bits (141), Expect = 4e-09,   Method: Compositional matrix adjust.
 Identities = 32/106 (30%), Positives = 57/106 (53%), Gaps = 2/106 (1%)
 Frame = +3

Query: 312 QDPYLLRTG--RFEEASTMPCRLALSPDTHVLALATGTNIHLFNTRRGEKEEYFECVHGE 369
           QD  LL +G    E AS     +ALSPD   +A+ + +++  ++    E+      +H E
Sbjct: 3   QDAKLLFSGPVTLEGASL----IALSPDGRTVAICSQSSVVFWDAVACEEMHTLHSLHAE 170

Query: 370 CIADLTFDITGRFLASCGDRAVRLFHNTPGHRAVVEEMQSLLKRAS 415
            I  L FD +  +L +CGD+ +++ HN PG++  + ++    K+AS
Sbjct: 171 PITALAFDNSNHYLVTCGDKHIQVIHNVPGYKTTIADLLHREKKAS 308
>00561
          Length = 1003

 Score = 47.8 bits (112), Expect = 9e-06,   Method: Compositional matrix adjust.
 Identities = 38/118 (32%), Positives = 59/118 (50%), Gaps = 7/118 (5%)
 Frame = -3

Query: 199 IMTASSDTTVLIWNLKGQVLSTINTNQ---MNNSH----AVISPCSRFVGSCGFTPDVKV 251
           I++AS D T+++W L     +     Q     +SH     V+S    +  S  +   +++
Sbjct: 965 IISASRDKTLIVWKLTRDEDTNYGYPQKRLYGHSHFISDVVLSSDGNYALSGSWDQTLRL 786

Query: 252 WEVCFGKKGEFQEVLRAFELKGHSASVHSFAFSNDSRRMASVSKDGTWKLWDTDVEYK 309
           W++  GK        R FE  GH+  V S AFS D+R++ S S+D T KLW+T  E K
Sbjct: 785 WDLAAGK------TTRRFE--GHTKDVLSVAFSADNRQIVSGSRDKTIKLWNTLAECK 636

 Score = 42.7 bits (99), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 49/215 (22%), Positives = 85/215 (39%), Gaps = 38/215 (17%)
 Frame = -3

Query: 82  LKSHSGNISCMDFSSNGKYLATCADDRTVRIW------STKDFLQREHRSMRANVELDHA 135
           L  HS  IS +  SS+G Y  + + D+T+R+W      +T+ F       +      D+ 
Sbjct: 878 LYGHSHFISDVVLSSDGNYALSGSWDQTLRLWDLAAGKTTRRFEGHTKDVLSVAFSADNR 699

Query: 136 TLVRFSPDCRAFIVWLANGDTLRVFKMTKREDGGFTFTATPEDFPKKHKAPII------- 188
            +V  S D +   +W    +TL   K T +EDG   + +    F   H  PII       
Sbjct: 698 QIVSGSRD-KTIKLW----NTLAECKFTIQEDGHTDWVSCVR-FSPNHSNPIIVSCGWDR 537

Query: 189 ------------------------NIGIADTGKFIMTASSDTTVLIWNLK-GQVLSTINT 223
                                    + ++  G    +   D+  L+W+L  G+ L T+  
Sbjct: 536 TVKVWNLANCKLKNNHHGHNGYLNTVTVSPDGSLCTSGGKDSKALLWDLNDGKNLYTLEH 357

Query: 224 NQMNNSHAVISPCSRFVGSCGFTPDVKVWEVCFGK 258
           N + N+    SP +R+     + P +K+W++   K
Sbjct: 356 NDIINA-LCFSP-NRYWLCVAYGPSIKIWDLACKK 258
>02147
          Length = 1547

 Score = 45.1 bits (105), Expect = 7e-05,   Method: Compositional matrix adjust.
 Identities = 63/267 (23%), Positives = 98/267 (36%), Gaps = 40/267 (14%)
 Frame = +2

Query: 80  AALKSHSGNISCMDFSSNGKYLATCADDRTVRIWSTKDFLQREHRSMRANVELDHATLVR 139
              + H G +     +      AT A D + +IW  +   + +  S +  V+      V 
Sbjct: 155 GTFEGHKGAVWGATLNREATRAATGAADFSAKIWDAEKGEELQTFSHKHIVKS-----VD 319

Query: 140 FSPDCRAFIVWLANGDTLRVFKMTKREDGGFTFTATPEDFPKKHKAPIINIGIADTGKFI 199
           FS D  A +   +N   L+VF +   +       A P+ F   H + I        GK I
Sbjct: 320 FSHDGTALLTG-SNEKLLKVFDLVNTD-------AEPKSFAG-HTSNIKGALFLSDGKRI 472

Query: 200 MTASSDTTVLIWNL-----------------------KGQVLSTINTN----------QM 226
           ++AS D TV +W+L                       K  ++ T + N          +M
Sbjct: 473 ISASDDKTVRLWSLETCQEVQQLTFDTPPTSLTLSPDKNTIIVTHSQNIAFYQADTLREM 652

Query: 227 NN-------SHAVISPCSRFVGSCGFTPDVKVWEVCFGKKGEFQEVLRAFELKGHSASVH 279
                    S A +    RF  + G   D K+++  +    E +        KGH   VH
Sbjct: 653 KKFEAEAPISSASLHQSERFFVAGG--EDFKMYKFDYETGKEIES------FKGHFGPVH 808

Query: 280 SFAFSNDSRRMASVSKDGTWKLWDTDV 306
              FS D    AS S+DGT +LW T +
Sbjct: 809 CVRFSPDGELYASGSEDGTLRLWQTTI 889

 Score = 39.7 bits (91), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 47/217 (21%), Positives = 84/217 (38%), Gaps = 11/217 (5%)
 Frame = +2

Query: 183 HKAPIINIGIADTGKFIMTASSDTTVLIWNL-KGQVLSTINTNQMNNSHAVISPCSRFVG 241
           HK  +    +        T ++D +  IW+  KG+ L T      ++ H V S      G
Sbjct: 170 HKGAVWGATLNREATRAATGAADFSAKIWDAEKGEELQT-----FSHKHIVKSVDFSHDG 334

Query: 242 SCGFTPDVKVWEVCFGKKGEFQEVLRAFEL----------KGHSASVHSFAFSNDSRRMA 291
           +   T             G  +++L+ F+L           GH++++    F +D +R+ 
Sbjct: 335 TALLT-------------GSNEKLLKVFDLVNTDAEPKSFAGHTSNIKGALFLSDGKRII 475

Query: 292 SVSKDGTWKLWDTDVEYKKQQDPYLLRTGRFEEASTMPCRLALSPDTHVLALATGTNIHL 351
           S S D T +LW  +   + QQ  +           T P  L LSPD + + +    NI  
Sbjct: 476 SASDDKTVRLWSLETCQEVQQLTF----------DTPPTSLTLSPDKNTIIVTHSQNIAF 625

Query: 352 FNTRRGEKEEYFECVHGECIADLTFDITGRFLASCGD 388
           +      + + FE      I+  +   + RF  + G+
Sbjct: 626 YQADTLREMKKFEAE--APISSASLHQSERFFVAGGE 730

 Score = 36.6 bits (83), Expect = 0.023,   Method: Compositional matrix adjust.
 Identities = 21/75 (28%), Positives = 37/75 (49%)
 Frame = +2

Query: 81  ALKSHSGNISCMDFSSNGKYLATCADDRTVRIWSTKDFLQREHRSMRANVELDHATLVRF 140
           + K H G + C+ FS +G+  A+ ++D T+R+W T   + R +   +  +  D A     
Sbjct: 779 SFKGHFGPVHCVRFSPDGELYASGSEDGTLRLWQTT--IGRTYGLWKCVIP-DEADAQNS 949

Query: 141 SPDCRAFIVWLANGD 155
           +PD +A   W    D
Sbjct: 950 TPDVKAES*WTGRSD 994
>01249
          Length = 1743

 Score = 44.3 bits (103), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 47/190 (24%), Positives = 87/190 (45%), Gaps = 15/190 (7%)
 Frame = -1

Query: 131  ELDHATLVRFSPDCRAFIVWLANG-----DTLRVFKMTKREDGGFTFTATPEDFPKKHKA 185
            + + AT ++F+ D   F+V  ++G     D  RV   T +   G      P      H  
Sbjct: 1374 DFNEATKIQFTDDGSQFVVATSSGHLNIWDFARVVTTTSQRARGLK----PGRTINAHSE 1207

Query: 186  PI--INIGIADTGKFIMTASSDTTVLIWN-LKGQVLSTINTNQMNNSHAVISPCSRFVGS 242
            PI  +++G       + ++SSD T  +W+ L G +L T+   +      ++     F+ +
Sbjct: 1206 PITGLHVGCGGPAARVASSSSDGTCKLWDMLSGALLRTM-VYETGVGCLIMDKQEHFLLA 1030

Query: 243  CGFTPDVKVWEVCFGKKGEFQ-----EVLRAFE--LKGHSASVHSFAFSNDSRRMASVSK 295
                 D+ +    FG+  + +        +A E  L+GHS +V   AFS+D +R+AS S+
Sbjct: 1029 GLDNGDI-LCSPLFGQISQSEVFVSKHTTKAGERVLQGHSDAVTCLAFSSDGQRLASGSQ 853

Query: 296  DGTWKLWDTD 305
            +G   +W+ +
Sbjct: 852  NGKVIIWNME 823

 Score = 32.3 bits (72), Expect = 0.34,   Method: Compositional matrix adjust.
 Identities = 13/34 (38%), Positives = 23/34 (67%)
 Frame = -1

Query: 81  ALKSHSGNISCMDFSSNGKYLATCADDRTVRIWS 114
            L+ HS  ++C+ FSS+G+ LA+ + +  V IW+
Sbjct: 930 VLQGHSDAVTCLAFSSDGQRLASGSQNGKVIIWN 829
>03387
          Length = 1891

 Score = 43.5 bits (101), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 62/279 (22%), Positives = 110/279 (39%), Gaps = 30/279 (10%)
 Frame = +1

Query: 82  LKSHSGNISCMDFSSN-GKYLATCADDRTVRIWSTKDFLQREHRSMRANV---------- 130
           LK H      + ++ N   +L + +DD T+ +W      QRE R + A+           
Sbjct: 349 LKGHQKEGYGLSWNPNLNGHLLSASDDHTICLWDINS-TQRESRVVDAHTIFTGHTSVVE 525

Query: 131 ----ELDHATLVRFSPDCRAFIVWLANGDTLRVFKMTKREDGGFTFTATPEDFPKKHKAP 186
                L H +L     D +  ++W    +T                T+ P      H A 
Sbjct: 526 DVAWHLLHESLFGSVADDQKLMIWDTRSNT----------------TSKPSHVVDAHTAE 657

Query: 187 IINIGIADTGKFIM-TASSDTTVLIWNLKGQVLS--TINTNQMNNSHAVISPCSR-FVGS 242
           +  +      +FI+ T S+D TV +W+L+   L   +  +++        SP +   + S
Sbjct: 658 VNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPHNETILAS 837

Query: 243 CGFTPDVKVWEVCFGKKGEFQ----------EVLRAFELKGHSASVHSFAFS-NDSRRMA 291
            G    + VW++   K GE Q          E+L  F   GH+A +  F+++ N+   + 
Sbjct: 838 SGTDRRLHVWDLS--KIGEEQLPEDAEDGPPELL--FIHGGHTAKISDFSWNPNEPWIVC 1005

Query: 292 SVSKDGTWKLWDTDVEYKKQQDPYLLRTGRFEEASTMPC 330
           SVS+D   ++W         +DP     G  E + ++ C
Sbjct: 1006SVSEDNIMQVWQMAENIYSDEDPDAAGGGDLEAS*SVVC 1122
>02960
          Length = 1577

 Score = 43.1 bits (100), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 41/120 (34%), Positives = 56/120 (46%), Gaps = 7/120 (5%)
 Frame = +2

Query: 200 MTASSDTTVLIWNLKGQVLSTI--NTNQMNN----SHAVISPCSRFV-GSCGFTPDVKVW 252
           ++ S D TV +W+ KG+ + TI  +T+ +       H   S  S FV GS   T  V  W
Sbjct: 527 LSGSYDNTVRLWSTKGEAIMTIPGHTSPVKCVAWIKHDESSGVSTFVTGSHDQTALVWQW 706

Query: 253 EVCFGKKGEFQEVLRAFELKGHSASVHSFAFSNDSRRMASVSKDGTWKLWDTDVEYKKQQ 312
           +       E  EV      +GH+ASV   A S DS++M + S D   KLW TD      Q
Sbjct: 707 Q------RETNEVDCRLSCRGHAASVDCVAVSPDSQQMCTGSWDKMLKLWSTDCNVDGDQ 868
>27465
          Length = 658

 Score = 42.7 bits (99), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 34/128 (26%), Positives = 58/128 (45%), Gaps = 3/128 (2%)
 Frame = -1

Query: 181 KKHKAPIINIGIADTGKFIMTASSDTTVLIWNL-KGQVLSTINTNQMNNSHAVI--SPCS 237
           + H  P+ N+    +G   +T S D T  IW+    + L T+  ++ N  +A+   +P  
Sbjct: 370 RAHILPLTNVAFNKSGSSFITGSYDRTCKIWDTASAEELHTLEGHR-NVVYAIAFNNPFG 194

Query: 238 RFVGSCGFTPDVKVWEVCFGKKGEFQEVLRAFELKGHSASVHSFAFSNDSRRMASVSKDG 297
             V +  F    K+W    GK            L+GH+A +   +F+  S  +A+ S D 
Sbjct: 193 DKVITGSFDKTCKLWSTADGKCYH--------TLRGHTAEIVCVSFNPSSTLIATGSMDT 38

Query: 298 TWKLWDTD 305
           T +LWD +
Sbjct: 37  TCRLWDVE 14

 Score = 34.3 bits (77), Expect = 0.10,   Method: Compositional matrix adjust.
 Identities = 35/151 (23%), Positives = 64/151 (42%)
 Frame = -1

Query: 64  RKEKPQQHSFTHPLLAAALKSHSGNISCMDFSSNGKYLATCADDRTVRIWSTKDFLQREH 123
           RK +P+     H  L   L++H   ++ + F+ +G    T + DRT +IW T      E 
Sbjct: 421 RKTRPKDDH--HFYLFKVLRAHILPLTNVAFNKSGSSFITGSYDRTCKIWDTAS--AEEL 254

Query: 124 RSMRANVELDHATLVRFSPDCRAFIVWLANGDTLRVFKMTKREDGGFTFTATPEDFPKKH 183
            ++  +  + +A  + F+     F   +  G   +  K+    DG    T       + H
Sbjct: 253 HTLEGHRNVVYA--IAFN---NPFGDKVITGSFDKTCKLWSTADGKCYHTL------RGH 107

Query: 184 KAPIINIGIADTGKFIMTASSDTTVLIWNLK 214
            A I+ +    +   I T S DTT  +W+++
Sbjct: 106 TAEIVCVSFNPSSTLIATGSMDTTCRLWDVE 14
>17598
          Length = 875

 Score = 41.6 bits (96), Expect = 6e-04,   Method: Compositional matrix adjust.
 Identities = 45/181 (24%), Positives = 86/181 (47%), Gaps = 5/181 (2%)
 Frame = +1

Query: 84  SHSGNISCMDFSSNGKYLATCADDRTVRIWSTKDFLQREHRSMRANVELDHATLVRFSPD 143
           SH+ +   + FS + + +A+   D+ ++IW+T   +     ++ AN   D  T V+F  D
Sbjct: 241 SHTRDALAVAFSPDNRQIASGGRDKALKIWNT---VGECKFTVDANSHQDWVTCVKFHQD 411

Query: 144 CRAFIVWLANGD-TLRVFK---MTKREDGGFTFTATPEDFPKKHKAPIINIGIADTGKFI 199
            ++ +V  A+ D T++V+    MT +     TF          HK  I  I +A    ++
Sbjct: 412 AKSPLVVSASMDKTIKVWDNQTMTLKH----TFVG--------HKTQINAIDLALKTYYL 555

Query: 200 MTASSDTTVLIWNLK-GQVLSTINTNQMNNSHAVISPCSRFVGSCGFTPDVKVWEVCFGK 258
            + S D  V+ WN++ G  L  I+ +   N  AV    +++    G +  +++W++   K
Sbjct: 556 ASGSKDGIVMTWNIQNGTFLGKIDCDCEVN--AVKFSPNKYWLFVGTSEGIQIWDLPNQK 729

Query: 259 K 259
           K
Sbjct: 730 K 732

 Score = 35.8 bits (81), Expect = 0.035,   Method: Compositional matrix adjust.
 Identities = 32/124 (25%), Positives = 57/124 (45%), Gaps = 11/124 (8%)
 Frame = +1

Query: 197 KFIMTASSDTTVLIWNLK-----------GQVLSTINTNQMNNSHAVISPCSRFVGSCGF 245
           +F++    D  +++W+L            G    T+  +    S   +S  SR+V S  +
Sbjct: 4   EFLIXGGRDKLLIVWDLVPRKDGDEDETWGGPRRTLQGHSHFVSDVSLSADSRYVLSSSW 183

Query: 246 TPDVKVWEVCFGKKGEFQEVLRAFELKGHSASVHSFAFSNDSRRMASVSKDGTWKLWDTD 305
              +++W++   KKG      R F    H+    + AFS D+R++AS  +D   K+W+T 
Sbjct: 184 DATLRLWDI---KKGN---TTRRF--ISHTRDALAVAFSPDNRQIASGGRDKALKIWNTV 339

Query: 306 VEYK 309
            E K
Sbjct: 340 GECK 351

 Score = 35.0 bits (79), Expect = 0.064,   Method: Compositional matrix adjust.
 Identities = 31/94 (32%), Positives = 41/94 (43%), Gaps = 2/94 (2%)
 Frame = +1

Query: 251 VWEVCFGKKGEFQEVLRA--FELKGHSASVHSFAFSNDSRRMASVSKDGTWKLWDTDVEY 308
           VW++   K G+  E        L+GHS  V   + S DSR + S S D T +LWD     
Sbjct: 43  VWDLVPRKDGDEDETWGGPRRTLQGHSHFVSDVSLSADSRYVLSSSWDATLRLWDI---- 210

Query: 309 KKQQDPYLLRTGRFEEASTMPCRLALSPDTHVLA 342
           KK        T RF   +     +A SPD   +A
Sbjct: 211 KKGN-----TTRRFISHTRDALAVAFSPDNRQIA 297

 Score = 33.5 bits (75), Expect = 0.17,   Method: Compositional matrix adjust.
 Identities = 59/301 (19%), Positives = 102/301 (33%), Gaps = 11/301 (3%)
 Frame = +1

Query: 64  RKEKPQQHSFTHPLLAAALKSHSGNISCMDFSSNGKYLATCADDRTVRIWSTKDFLQREH 123
           RK+  +  ++  P     L+ HS  +S +  S++ +Y+ + + D T+R+W  K    + +
Sbjct: 61  RKDGDEDETWGGP--RRTLQGHSHFVSDVSLSADSRYVLSSSWDATLRLWDIK----KGN 222

Query: 124 RSMRANVELDHATLVRFSPDCRAFIVWLANGDTLRVFKMTKREDGGFTFTATPEDFPKKH 183
            + R       A  V FSPD                                        
Sbjct: 223 TTRRFISHTRDALAVAFSPD---------------------------------------- 282

Query: 184 KAPIINIGIADTGKFIMTASSDTTVLIWNLKGQVLSTINTNQMNNSHAVISPCSRF---- 239
                N  IA  G+       D  + IWN  G+   T++ N    SH     C +F    
Sbjct: 283 -----NRQIASGGR-------DKALKIWNTVGECKFTVDAN----SHQDWVTCVKFHQDA 414

Query: 240 ----VGSCGFTPDVKVWEVCFGKKGEFQEVLRAFELKGHSASVHSFAFSNDSRRMASVSK 295
               V S      +KVW+         Q +       GH   +++   +  +  +AS SK
Sbjct: 415 KSPLVVSASMDKTIKVWD--------NQTMTLKHTFVGHKTQINAIDLALKTYYLASGSK 570

Query: 296 DGTWKLWDTDVEYKKQQDPYLLRTGRFEEASTMPCR---LALSPDTHVLALATGTNIHLF 352
           DG    W+             ++ G F       C    +  SP+ + L + T   I ++
Sbjct: 571 DGIVMTWN-------------IQNGTFLGKIDCDCEVNAVKFSPNKYWLFVGTSEGIQIW 711

Query: 353 N 353
           +
Sbjct: 712 D 714
>30256
          Length = 961

 Score = 41.6 bits (96), Expect = 6e-04,   Method: Compositional matrix adjust.
 Identities = 57/223 (25%), Positives = 100/223 (44%), Gaps = 1/223 (0%)
 Frame = +3

Query: 82  LKSHSGNISCMDFSSNGKYLATCADDRTVRIWSTKDFLQREHRSMRANVELDHATLVRFS 141
           L  HS  + C+  S  GK + + + D T+R+W     ++  H     NV L H   VR  
Sbjct: 150 LYGHSSTVRCLSLS--GKKVVSGSRDATLRVWD----IESGHC---LNVLLGHMAAVRCV 302

Query: 142 PDCRAFIVWLANGDTLRVFKMTKREDGGFTFTATPEDFPKKHKAPIINIGIADTGKFIMT 201
                 +V  A   T+RV+            TA+     + H   + ++     G ++++
Sbjct: 303 QYDGKRVVSGAXDYTVRVWDPD---------TASCLHTLQGHTNRVYSLQF--DGVYVVS 449

Query: 202 ASSDTTVLIWNLK-GQVLSTINTNQMNNSHAVISPCSRFVGSCGFTPDVKVWEVCFGKKG 260
            S DT++ +W+++ G+++ T+  +Q   S   +       G+   T  VKVW+V  GK  
Sbjct: 450 GSLDTSIRVWDVRCGKLVHTLMGHQSLTSGLELKDNLLVSGNADST--VKVWDVHTGKC- 620

Query: 261 EFQEVLRAFELKGHSASVHSFAFSNDSRRMASVSKDGTWKLWD 303
             Q +L   +   H ++V    F  + + + + S DGT KLWD
Sbjct: 621 -LQTLLGPNK---HRSAVTCLQF--NKKFVVTCSDDGTVKLWD 731

 Score = 35.0 bits (79), Expect = 0.061,   Method: Compositional matrix adjust.
 Identities = 34/156 (21%), Positives = 62/156 (39%), Gaps = 4/156 (2%)
 Frame = +3

Query: 63  VRKEKPQQHSFTHPLLAAALKSHSGNISCMDFSSNGKYLATCADDRTVRIWSTK----DF 118
           VR   P   S  H L     + H+  +  + F  +G Y+ + + D ++R+W  +      
Sbjct: 348 VRVWDPDTASCLHTL-----QGHTNRVYSLQF--DGVYVVSGSLDTSIRVWDVRCGKLVH 506

Query: 119 LQREHRSMRANVELDHATLVRFSPDCRAFIVWLANGDTLRVFKMTKREDGGFTFTATPED 178
               H+S+ + +EL    LV  + D    +  +  G  L+                    
Sbjct: 507 TLMGHQSLTSGLELKDNLLVSGNADSTVKVWDVHTGKCLQTLL----------------- 635

Query: 179 FPKKHKAPIINIGIADTGKFIMTASSDTTVLIWNLK 214
            P KH++ +  +      KF++T S D TV +W+L 
Sbjct: 636 GPNKHRSAVTCLQFNK--KFVVTCSDDGTVKLWDLN 737

 Score = 34.7 bits (78), Expect = 0.084,   Method: Compositional matrix adjust.
 Identities = 15/38 (39%), Positives = 26/38 (68%), Gaps = 2/38 (5%)
 Frame = +3

Query: 85  HSGNISCMDFSSNGKYLATCADDRTVRIW--STKDFLQ 120
           H   ++C+ F  N K++ TC+DD TV++W  +T DF++
Sbjct: 648 HRSAVTCLQF--NKKFVVTCSDDGTVKLWDLNTGDFIR 755
>19498
          Length = 903

 Score = 41.2 bits (95), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 39/162 (24%), Positives = 70/162 (43%), Gaps = 13/162 (8%)
 Frame = -1

Query: 63  VRKEKPQQHSFTHPLLAAALKSHSGNISCMDFSSNGKYLATCADDRTVRIWSTKDFLQRE 122
           +R EK +      P +   + SH G ++C+ +S NGK+LA+  DD+ + IW         
Sbjct: 852 IRDEKEEADDDV-PRVLCQMDSHLGCVNCVRWSENGKFLASGGDDKLIMIWQISRGFG-S 679

Query: 123 HRSMRANVE-LDH----ATLVRFSPDCRAFI-----VWLAN---GDTLRVFKMTKREDGG 169
            +S  +NV  L+H    ATL   + D          +WLA+    +T+ V+   K  +  
Sbjct: 678 GKSFGSNVTILEHWRSVATLRGHAGDVLDLAWSPQDLWLASCSVDNTIVVWNALKFSEQV 499

Query: 170 FTFTATPEDFPKKHKAPIINIGIADTGKFIMTASSDTTVLIW 211
                      + H   +  +     G+++ + S D T+ +W
Sbjct: 498 AVI--------RGHAGMVKGVTWDPVGRYLASQSDDKTLRVW 397

 Score = 39.3 bits (90), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 14/40 (35%), Positives = 27/40 (67%)
 Frame = -1

Query: 79  AAALKSHSGNISCMDFSSNGKYLATCADDRTVRIWSTKDF 118
            A ++ H+G +  + +   G+YLA+ +DD+T+R+W T D+
Sbjct: 501 VAVIRGHAGMVKGVTWDPVGRYLASQSDDKTLRVWRTSDW 382

 Score = 33.1 bits (74), Expect = 0.22,   Method: Compositional matrix adjust.
 Identities = 37/171 (21%), Positives = 70/171 (40%), Gaps = 21/171 (12%)
 Frame = -1

Query: 193 ADTGKFIMTASSDTTVLIWNLK------------------GQVLSTINTNQMNNSHAVIS 234
           ++ GKF+ +   D  ++IW +                    + ++T+  +  +      S
Sbjct: 759 SENGKFLASGGDDKLIMIWQISRGFGSGKSFGSNVTILEHWRSVATLRGHAGDVLDLAWS 580

Query: 235 PCSRFVGSCGFTPDVKVWEVCFGKKGEFQEVLRAFELKGHSASVHSFAFSNDSRRMASVS 294
           P   ++ SC     + VW        +F E +    ++GH+  V    +    R +AS S
Sbjct: 579 PQDLWLASCSVDNTIVVWNAL-----KFSEQVAV--IRGHAGMVKGVTWDPVGRYLASQS 421

Query: 295 KDGTWKLWDTDVEYKKQQDPYLLRTGRFEE--ASTMPCRLALSPD-THVLA 342
            D T ++W T  ++K++          F+E   +T   RL  SPD  HV++
Sbjct: 420 DDKTLRVWRTS-DWKEET----CVKSCFKECGGTTHVLRLNWSPDGNHVVS 283
>13335
          Length = 863

 Score = 39.7 bits (91), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 56/225 (24%), Positives = 87/225 (38%), Gaps = 16/225 (7%)
 Frame = +1

Query: 94  FSSNGKYLATCADDRTVRIWST------KDFLQREHRSMRANVELDHATLVRFSPDCRAF 147
           FS +  +L + +DD T+ +W        + ++  E   M      +   LV  SP+   +
Sbjct: 85  FSPSSSHLVSGSDDDTICMWEVATQKLVRSYVGHEDSVMALAYSPNGHYLVSGSPNGDLY 264

Query: 148 IVWLANGDTLRVFKMTKREDGGFTFTATPEDFPKKHKAPIINIGIADTGKFIMTASSDTT 207
            VW A+    R   +T R D         E  P    A   N    +    + T   D  
Sbjct: 265 -VWDASFGHCR--HLTLRVDAHDLGVTCCEFSPTFGTACAENSSTCNL--LLATGGKDNL 429

Query: 208 VLIWNLKGQVLSTINTNQMNNSHAVISPCSRFVGSCGFTPDVKVWEVCFGKKGEFQEVLR 267
           + +W    QV S   T Q  +   ++S  S  V +C F+P   +        G F + +R
Sbjct: 430 IKLWTFSAQVGSPEVTLQCRD---ILSGHSDLVMACAFSPSSALLA-----SGSFDKSVR 585

Query: 268 AFE-LKG---------HSASVHSFAFSNDSRRMASVSKDGTWKLW 302
            ++ +KG         HS  V   AFS D   +AS S D   K+W
Sbjct: 586 LWDSVKGVALFSIEACHSRFVTCCAFSIDGTLLASGSMDRIIKIW 720

 Score = 38.9 bits (89), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 51/209 (24%), Positives = 89/209 (42%), Gaps = 17/209 (8%)
 Frame = +1

Query: 208 VLIWNLKGQVLSTINTNQMNNSHAV--ISPCSRFVGSCGFTPDVKVWEVCFGKKGEFQEV 265
           V++W++K   +     +   +S  V   SP S  + S      + +WEV        Q++
Sbjct: 4   VIVWDVKTGSIKGEYQHASKSSIRVCKFSPSSSHLVSGSDDDTICMWEV------ATQKL 165

Query: 266 LRAFELKGHSASVHSFAFSNDSRRMASVSKDGTWKLWDTDVEYKK----QQDPYLLRTGR 321
           +R++   GH  SV + A+S +   + S S +G   +WD    + +    + D + L    
Sbjct: 166 VRSY--VGHEDSVMALAYSPNGHYLVSGSPNGDLYVWDASFGHCRHLTLRVDAHDLGVTC 339

Query: 322 FEEASTMPCRLALSPDTHVLALATGTNIHL-----FNTRRGEKEEYFEC-----VHGECI 371
            E + T     A +  T  L LATG   +L     F+ + G  E   +C      H + +
Sbjct: 340 CEFSPTFGTACAENSSTCNLLLATGGKDNLIKLWTFSAQVGSPEVTLQCRDILSGHSDLV 519

Query: 372 ADLTFDITGRFLASCG-DRAVRLFHNTPG 399
               F  +   LAS   D++VRL+ +  G
Sbjct: 520 MACAFSPSSALLASGSFDKSVRLWDSVKG 606

 Score = 30.4 bits (67), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 13/33 (39%), Positives = 20/33 (60%)
 Frame = +1

Query: 85  HSGNISCMDFSSNGKYLATCADDRTVRIWSTKD 117
           HS  ++C  FS +G  LA+ + DR ++IW   D
Sbjct: 634 HSRFVTCCAFSIDGTLLASGSMDRIIKIWKLTD 732
>12806
          Length = 961

 Score = 39.7 bits (91), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 43/182 (23%), Positives = 76/182 (41%), Gaps = 15/182 (8%)
 Frame = +3

Query: 195 TGKFIMTASSDTTVLIWNL-------KGQVLSTINTNQMNNSHAV----ISPCSRFVGSC 243
           T  F+++   D  +++W+L       + Q           +SH +    +S  SRF  S 
Sbjct: 42  TKPFLISGGRDNNIIVWDL*PKKDGDEDQTWGVPRKTLTGHSHFISDLALSADSRFALSS 221

Query: 244 GFTPDVKVWEVCFGKKGEFQEVLRAFELKGHSASVHSFAFSNDSRRMASVSKDGTWKLWD 303
            +   +++W++   KKG             H+  V + AFS D+R++AS  +D   K+W+
Sbjct: 222 SWDATLRLWDI---KKGSTTS-----RFINHTRDVLTVAFSPDNRQIASGGRDKNLKIWN 377

Query: 304 TDVEYKKQQDPY----LLRTGRFEEASTMPCRLALSPDTHVLALATGTNIHLFNTRRGEK 359
              E K   D       +   RF + +  P  ++ S D  +      T + L NT  G K
Sbjct: 378 IMGECKYTVDANAHTDWVTCVRFHQDTKNPIVVSASNDKTIKVWDNHT-MTLKNTFVGHK 554

Query: 360 EE 361
            +
Sbjct: 555 AQ 560
>19949
          Length = 903

 Score = 39.3 bits (90), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 24/69 (34%), Positives = 34/69 (49%)
 Frame = +2

Query: 235 PCSRFVGSCGFTPDVKVWEVCFGKKGEFQEVLRAFELKGHSASVHSFAFSNDSRRMASVS 294
           P   +  S     +VK+W++   +KG        +  KGH+  V    FS D R +AS S
Sbjct: 23  PYGAYTASGSMDCNVKLWDI--RRKGCI------YTYKGHTGCVCCLRFSPDGRWIASAS 178

Query: 295 KDGTWKLWD 303
           +DG  KLWD
Sbjct: 179 EDGLVKLWD 205

 Score = 35.4 bits (80), Expect = 0.042,   Method: Compositional matrix adjust.
 Identities = 25/95 (26%), Positives = 41/95 (43%)
 Frame = +2

Query: 83  KSHSGNISCMDFSSNGKYLATCADDRTVRIWSTKDFLQREHRSMRANVELDHATLVRFSP 142
           K H+G + C+ FS +G+++A+ ++D  V++W     L          +  D    + F P
Sbjct: 110 KGHTGCVCCLRFSPDGRWIASASEDGLVKLWD----LTAGKLLTDLKLHRDAVNTIEFHP 277

Query: 143 DCRAFIVWLANGDTLRVFKMTKREDGGFTFTATPE 177
               F+  LA+G   R  K    E      T  PE
Sbjct: 278 --HEFL--LASGSADRTVKFWDLETFQLISTTEPE 370

 Score = 30.4 bits (67), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 31/133 (23%), Positives = 54/133 (40%), Gaps = 1/133 (0%)
 Frame = +2

Query: 89  ISCMDFSSNGKYLATCADDRTVRIWSTKDFLQREHRSMRANVELDHATLVRFSPDCRAFI 148
           +  +DF   G Y A+ + D  V++W     ++R+               +RFSPD R   
Sbjct: 2   VKSLDFHPYGAYTASGSMDCNVKLWD----IRRKGCIYTYKGHTGCVCCLRFSPDGR--- 160

Query: 149 VWLANGDTLRVFKMTKREDGGFTFTATPEDFPKKHKAPIINIGIADTGKFIMTASSDTTV 208
            W+A+     + K+     G            K H+  +  I        + + S+D TV
Sbjct: 161 -WIASASEDGLVKLWDLTAGKLLTDL------KLHRDAVNTIEFHPHEFLLASGSADRTV 319

Query: 209 LIWNLKG-QVLST 220
             W+L+  Q++ST
Sbjct: 320 KFWDLETFQLIST 358

 Score = 30.0 bits (66), Expect = 1.9,   Method: Compositional matrix adjust.
 Identities = 23/88 (26%), Positives = 41/88 (46%), Gaps = 5/88 (5%)
 Frame = +2

Query: 78  LAAALKSHSGNISCMDFSSNGKYLATCADDRTVRIWSTKDF-----LQREHRSMRANVEL 132
           L   LK H   ++ ++F  +   LA+ + DRTV+ W  + F      + E  S+R+    
Sbjct: 221 LLTDLKLHRDAVNTIEFHPHEFLLASGSADRTVKFWDLETFQLISTTEPEANSIRS---- 388

Query: 133 DHATLVRFSPDCRAFIVWLANGDTLRVF 160
                + F PD     ++  + DTL+V+
Sbjct: 389 -----ILFHPD--GVCLYSGSKDTLKVY 451
>30176
          Length = 365

 Score = 38.9 bits (89), Expect = 0.004,   Method: Composition-based stats.
 Identities = 14/32 (43%), Positives = 22/32 (68%)
 Frame = +2

Query: 82  LKSHSGNISCMDFSSNGKYLATCADDRTVRIW 113
           LKSH+  +  + F   G  LA+C+DD+T++IW
Sbjct: 8   LKSHTSTVWNLTFDKTGTRLASCSDDKTIKIW 103

 Score = 31.2 bits (69), Expect = 0.79,   Method: Composition-based stats.
 Identities = 13/32 (40%), Positives = 19/32 (59%)
 Frame = +2

Query: 271 LKGHSASVHSFAFSNDSRRMASVSKDGTWKLW 302
           LK H+++V +  F     R+AS S D T K+W
Sbjct: 8   LKSHTSTVWNLTFDKTGTRLASCSDDKTIKIW 103
>31864
          Length = 545

 Score = 37.0 bits (84), Expect = 0.018,   Method: Compositional matrix adjust.
 Identities = 40/136 (29%), Positives = 58/136 (42%), Gaps = 10/136 (7%)
 Frame = +2

Query: 183 HKAPIINIGIADTGKFIMTASSDTTVLIWNLKGQV-LSTINTNQMNNSHAVISPCSRFVG 241
           H   I ++ ++  G   +TAS DTT  +++ +  + L T  T +  NS A ISP    V 
Sbjct: 47  HTGGINDMQLSKDGTMFVTASKDTTAKLFDSESLMCLKTYKTERPVNS-AAISPILDHV- 220

Query: 242 SCGFTPDVKVWEVCFGKKGEFQEVLRAFEL---------KGHSASVHSFAFSNDSRRMAS 292
             G   D         K G+F    R F L         KGH   ++S AF  D +  AS
Sbjct: 221 VLGGGQDAMEVTTTSTKAGKFDS--RFFHLIYEEEFARLKGHFGPINSLAFHPDGKSYAS 394

Query: 293 VSKDGTWKLWDTDVEY 308
             +DG  ++   D  Y
Sbjct: 395 GGEDGFVRVKSFDSTY 442
>17602
          Length = 481

 Score = 37.0 bits (84), Expect = 0.018,   Method: Compositional matrix adjust.
 Identities = 36/141 (25%), Positives = 65/141 (46%), Gaps = 2/141 (1%)
 Frame = +3

Query: 82  LKSHSGNISCMDFSSNGKYLATCADDRTVRIWSTKDFLQREHRSMRANVELDH--ATLVR 139
           L +HS  ++ + F+ +G  + + + D   RIW T        + +   ++ D+   + V+
Sbjct: 42  LPAHSDPVTAVHFNRDGSLIVSSSYDGLCRIWDTA-----SGQCLXTLIDDDNPPVSFVK 206

Query: 140 FSPDCRAFIVWLANGDTLRVFKMTKREDGGFTFTATPEDFPKKHKAPIINIGIADTGKFI 199
           FSP+ + +I+     +TL+++  +K   G    T       +  K  I        GK+I
Sbjct: 207 FSPNGK-YILAATLDNTLKLWDYSK---GKCLKTYVGH---RNEKYCIFANFSVTGGKWI 365

Query: 200 MTASSDTTVLIWNLKGQVLST 220
           ++ S D  V IWNL  Q  ST
Sbjct: 366 VSGSEDNMVYIWNLLDQGDST 428
>02090
          Length = 1841

 Score = 36.2 bits (82), Expect = 0.025,   Method: Compositional matrix adjust.
 Identities = 41/208 (19%), Positives = 83/208 (39%), Gaps = 4/208 (1%)
 Frame = -3

Query: 206  TTVLIWNLKG---QVLSTINTNQMNNSHAVISPCSRFVGSCGFTPDVKVWEVCFGKKGEF 262
            +T+ IW+L     ++ + + ++        ISP  +   SC    ++ VW++        
Sbjct: 1692 STLSIWDLATPTPRIKAELTSSAPACYALAISPDGKVCFSCCSDGNIAVWDL------HN 1531

Query: 263  QEVLRAFELKGHSASVHSFAFSNDSRRMASVSKDGTWKLWDTDVEYKKQQDPYLLRTGRF 322
            Q ++R F+  GH+        S D  ++ +   D T + WD     + QQ  +       
Sbjct: 1530 QTLVRQFQ--GHTDGASCIDISPDGTKLWTGGLDNTVRSWDLREGRQLQQHDF------- 1378

Query: 323  EEASTMPCRLALSPDTHVLALAT-GTNIHLFNTRRGEKEEYFECVHGECIADLTFDITGR 381
               S+    L   P    LA+    +N+ + +  + +K +    +H  C+  L F   G+
Sbjct: 1377 ---SSQIFSLGYCPTGEWLAVGMESSNVEVLHHSKPDKYQLH--LHESCVLSLKFAYCGK 1213

Query: 382  FLASCGDRAVRLFHNTPGHRAVVEEMQS 409
            +  S G   +     TP   ++ +  +S
Sbjct: 1212 WFVSTGKDNLLNAWRTPYGASIFQSKES 1129

 Score = 32.0 bits (71), Expect = 0.49,   Method: Compositional matrix adjust.
 Identities = 30/138 (21%), Positives = 53/138 (38%), Gaps = 4/138 (2%)
 Frame = -3

Query: 78   LAAALKSHSGNISCMDFSSNGKYLATCADDRTVRIWSTKDFLQREHRSMRANVELDHATL 137
            L    + H+   SC+D S +G  L T   D TVR W  ++  Q +     + +       
Sbjct: 1524 LVRQFQGHTDGASCIDISPDGTKLWTGGLDNTVRSWDLREGRQLQQHDFSSQI------- 1366

Query: 138  VRFSPDCRAFIVWLANG---DTLRVFKMTKREDGGFTFTATPEDFP-KKHKAPIINIGIA 193
              FS        WLA G     + V   +K           P+ +    H++ ++++  A
Sbjct: 1365 --FSLGYCPTGEWLAVGMESSNVEVLHHSK-----------PDKYQLHLHESCVLSLKFA 1225

Query: 194  DTGKFIMTASSDTTVLIW 211
              GK+ ++   D  +  W
Sbjct: 1224 YCGKWFVSTGKDNLLNAW 1171
>01462
          Length = 995

 Score = 36.2 bits (82), Expect = 0.030,   Method: Compositional matrix adjust.
 Identities = 18/55 (32%), Positives = 28/55 (50%)
 Frame = +2

Query: 249 VKVWEVCFGKKGEFQEVLRAFELKGHSASVHSFAFSNDSRRMASVSKDGTWKLWD 303
           + VW++      E  + L A E  GH   +H     ND++   S S+DGT ++WD
Sbjct: 269 IHVWDI------EAGQYLNAME--GHKDYIHKVVMKNDAQECVSASEDGTVRMWD 409
>15337
          Length = 860

 Score = 35.8 bits (81), Expect = 0.039,   Method: Compositional matrix adjust.
 Identities = 14/37 (37%), Positives = 23/37 (62%)
 Frame = -1

Query: 78  LAAALKSHSGNISCMDFSSNGKYLATCADDRTVRIWS 114
           L   +KS+ G + C+ +S +GKY+ T  +D  V +WS
Sbjct: 227 LIGTMKSYFGGLLCVCWSPDGKYIVTGGEDDLVTVWS 117
>15972
          Length = 1069

 Score = 35.4 bits (80), Expect = 0.047,   Method: Compositional matrix adjust.
 Identities = 30/117 (25%), Positives = 47/117 (40%), Gaps = 5/117 (4%)
 Frame = +3

Query: 176 PEDFPKKHKAPIINIGIADTGKFIMTASSDTTVLIWNLKGQVLSTINTNQMNNSHAVISP 235
           PE     HK P+ ++ +  +GK  +T S D T+ +W            N MN   A IS 
Sbjct: 213 PERTFSGHKGPVRHLAVHPSGKLTLTVSQDRTLRLW------------NNMNGRIAFISN 356

Query: 236 CSRFVGSCGFTPDVKVWEVCFGK-----KGEFQEVLRAFELKGHSASVHSFAFSNDS 287
                 S  + P    + V F         E + +LR+ +    S +V+S  F  D+
Sbjct: 357 MKEAAESVRWAPGGLYYVVAFRSHLDVYSVESKGLLRSIDT---SQTVNSVGFVTDT 518
>03044
          Length = 1952

 Score = 35.0 bits (79), Expect = 0.062,   Method: Compositional matrix adjust.
 Identities = 22/87 (25%), Positives = 41/87 (47%), Gaps = 1/87 (1%)
 Frame = -2

Query: 82   LKSHSGNISCMDFSSNGKYLATCADDRTVRIWSTKDFLQREHRS-MRANVELDHATLVRF 140
            L  H   ++ +D++     + TC  DR   +W+ +D   + H   +R N     AT V++
Sbjct: 1666 LGEHGQRVTGIDWAPKSNRIVTCGADRNAYVWTYQDGKWQPHLVILRIN---RAATCVKW 1496

Query: 141  SPDCRAFIVWLANGDTLRVFKMTKRED 167
            SP+   F V    G + R+  ++  E+
Sbjct: 1495 SPEENKFAV----GSSARLISVSYYEE 1427
>26107
          Length = 1338

 Score = 34.7 bits (78), Expect = 0.089,   Method: Compositional matrix adjust.
 Identities = 28/99 (28%), Positives = 44/99 (44%), Gaps = 6/99 (6%)
 Frame = -3

Query: 239 FVGSCGFTPDVKVWEVCFGKK-GEFQEV----LRAFELKGHSASVHSFAF-SNDSRRMAS 292
           F   C  +PD K      G+  G   EV     R   L GH+  V +  + S D  ++A+
Sbjct: 418 FFVRCAISPDGKYLLSGSGRNTGVIWEVDKPNKRPLFLIGHTEDVSAVDWCSTDVCKLAT 239

Query: 293 VSKDGTWKLWDTDVEYKKQQDPYLLRTGRFEEASTMPCR 331
           VS D + ++W  D   +  +DP  +    +  +S  PCR
Sbjct: 238 VSDDRSLRIWRPDARERHTEDP-TISGFAYSSSSGQPCR 125

 Score = 28.9 bits (63), Expect = 4.1,   Method: Compositional matrix adjust.
 Identities = 14/33 (42%), Positives = 24/33 (72%), Gaps = 1/33 (3%)
 Frame = -3

Query: 82  LKSHSGNISCMDF-SSNGKYLATCADDRTVRIW 113
           L  H+ ++S +D+ S++   LAT +DDR++RIW
Sbjct: 307 LIGHTEDVSAVDWCSTDVCKLATVSDDRSLRIW 209

 Score = 28.5 bits (62), Expect = 6.4,   Method: Compositional matrix adjust.
 Identities = 17/43 (39%), Positives = 23/43 (53%), Gaps = 1/43 (2%)
 Frame = -3

Query: 273 GHSASVHSFAFSNDS-RRMASVSKDGTWKLWDTDVEYKKQQDP 314
           GH  SV S A    S  + AS ++DG   LWD+ V  K++  P
Sbjct: 967 GHKCSVRSVASCPSSPAQCASGARDGHIMLWDSRVNKKREHQP 839
>11915
          Length = 737

 Score = 34.3 bits (77), Expect = 0.090,   Method: Compositional matrix adjust.
 Identities = 27/86 (31%), Positives = 36/86 (41%), Gaps = 1/86 (1%)
 Frame = +1

Query: 249 VKVWEVCFGKKGEFQEVLRAFELKGHSASVHSFAFSND-SRRMASVSKDGTWKLWDTDVE 307
           +K+W    GK           E+  H A+VH   F+ D S  + S S DGT KLW    E
Sbjct: 478 IKLWNCETGK--------LLIEMMDHKATVHDLHFAADNSLCLMSASHDGTVKLW----E 621

Query: 308 YKKQQDPYLLRTGRFEEASTMPCRLA 333
           +  Q D  +  T R        CR +
Sbjct: 622 FDDQGDCNMYLTLRTNAKHAFSCRWS 699
>12960
          Length = 550

 Score = 34.3 bits (77), Expect = 0.091,   Method: Compositional matrix adjust.
 Identities = 24/129 (18%), Positives = 50/129 (38%), Gaps = 6/129 (4%)
 Frame = +2

Query: 94  FSSNGKYLATCADDRTVRIWS------TKDFLQREHRSMRANVELDHATLVRFSPDCRAF 147
           FS + +Y  TC  D++V++W+       K ++   H  + A    D++ +     D    
Sbjct: 197 FSVDSRYCMTCGSDKSVKLWNPHRELFLKTYIGHGHEVLDAQGSGDNSQICSGGIDKTVV 376

Query: 148 IVWLANGDTLRVFKMTKREDGGFTFTATPEDFPKKHKAPIINIGIADTGKFIMTASSDTT 207
           +  +A+G  LR +                    + H   +  +   +    I++ S D T
Sbjct: 377 LFDVASGQALRKY--------------------RDHAGTVNCVKFNEESTVILSGSLDNT 496

Query: 208 VLIWNLKGQ 216
           V  W+ + +
Sbjct: 497 VRAWDTRSR 523

 Score = 28.9 bits (63), Expect = 4.3,   Method: Compositional matrix adjust.
 Identities = 10/34 (29%), Positives = 20/34 (58%)
 Frame = +2

Query: 83  KSHSGNISCMDFSSNGKYLATCADDRTVRIWSTK 116
           + H+G ++C+ F+     + + + D TVR W T+
Sbjct: 416 RDHAGTVNCVKFNEESTVILSGSLDNTVRAWDTR 517
>30297
          Length = 822

 Score = 34.3 bits (77), Expect = 0.099,   Method: Compositional matrix adjust.
 Identities = 18/50 (36%), Positives = 27/50 (54%)
 Frame = -1

Query: 66  EKPQQHSFTHPLLAAALKSHSGNISCMDFSSNGKYLATCADDRTVRIWST 115
           E P+  S   P +  + + H  ++SC+D     K L T A D TVR+W+T
Sbjct: 279 ETPETDS---PDVIQSWRGHVESVSCLDLVEQNKVLLTSAADCTVRMWTT 139
>19863
          Length = 502

 Score = 34.3 bits (77), Expect = 0.10,   Method: Compositional matrix adjust.
 Identities = 13/36 (36%), Positives = 26/36 (72%)
 Frame = +1

Query: 82  LKSHSGNISCMDFSSNGKYLATCADDRTVRIWSTKD 117
           L+ H+G ++ + FS +  +L +C++D TVRIW+ ++
Sbjct: 85  LQGHAGWVNDVHFSQDQCWLLSCSNDNTVRIWNIEE 192

 Score = 31.6 bits (70), Expect = 0.63,   Method: Compositional matrix adjust.
 Identities = 21/88 (23%), Positives = 37/88 (42%)
 Frame = +1

Query: 249 VKVWEVCFGKKGEFQEVLRAFELKGHSASVHSFAFSNDSRRMASVSKDGTWKLWDTDVEY 308
           + VW+V  G        ++   L+GH+  V+   FS D   + S S D T ++W+ +   
Sbjct: 43  IVVWDVENG--------VQKLRLQGHAGWVNDVHFSQDQCWLLSCSNDNTVRIWNIE--- 189

Query: 309 KKQQDPYLLRTGRFEEASTMPCRLALSP 336
           +  Q P ++   R +      C     P
Sbjct: 190 ESDQIPIVMEHKRAQGLKVTKCSKCGKP 273
>20271
          Length = 567

 Score = 33.5 bits (75), Expect = 0.19,   Method: Compositional matrix adjust.
 Identities = 34/128 (26%), Positives = 51/128 (39%), Gaps = 6/128 (4%)
 Frame = -1

Query: 95  SSNGKYLATCADDRTVRIWSTKDFLQREHRSMRANVELDHATLVRFSPDCRAFIVWLANG 154
           + N   L + ++D  +  WS  D L +   SM    EL H      +  C +F+   AN 
Sbjct: 537 TQNAHNLISVSNDGKLCSWSL-DMLSQPQDSM----ELQHKQSKSVAATCFSFLSGDANN 373

Query: 155 DTLRVFKMTKREDGGFTFTATPEDFPKKHKAPIINI------GIADTGKFIMTASSDTTV 208
             +   +            A   +  + H+ PI  I      G  D   F +TAS D TV
Sbjct: 372 FIVGSEECLVYSASRHGSKAGINEAYEGHQGPITAIDTHHAAGQIDFSPFFLTASFDWTV 193

Query: 209 LIWNLKGQ 216
            +WN+K Q
Sbjct: 192 KLWNIKEQ 169
>31474
          Length = 403

 Score = 33.5 bits (75), Expect = 0.19,   Method: Compositional matrix adjust.
 Identities = 24/96 (25%), Positives = 42/96 (43%), Gaps = 6/96 (6%)
 Frame = -3

Query: 195 TGKFIMTASSDTTVLIWNLKGQVLSTINTNQMNNSHAVI------SPCSRFVGSCGFTPD 248
           TG  + +  SD  + IW  +G   + +  + + ++H         SPC  ++ S  F   
Sbjct: 272 TGTLLASCGSDKIIKIWGKEGD--NWVCKSTLTDAHTRTVRSLGWSPCGNYLSSASFDAT 99

Query: 249 VKVWEVCFGKKGEFQEVLRAFELKGHSASVHSFAFS 284
             VW     K GEF+ +     L+GH   V + A++
Sbjct: 98  TAVWSR---KGGEFECIAT---LEGHENEVKAVAWA 9

 Score = 29.6 bits (65), Expect = 2.3,   Method: Compositional matrix adjust.
 Identities = 14/47 (29%), Positives = 24/47 (51%), Gaps = 7/47 (14%)
 Frame = -3

Query: 74  THPLLAAA-------LKSHSGNISCMDFSSNGKYLATCADDRTVRIW 113
           TH  +A A       L +H  +  C+ ++  G  LA+C  D+ ++IW
Sbjct: 362 THAKMAMATLEEVCCLSAHDEHAWCVAWNPTGTLLASCGSDKIIKIW 222

 Score = 29.3 bits (64), Expect = 3.2,   Method: Compositional matrix adjust.
 Identities = 19/69 (27%), Positives = 33/69 (47%)
 Frame = -3

Query: 234 SPCSRFVGSCGFTPDVKVWEVCFGKKGEFQEVLRAFELKGHSASVHSFAFSNDSRRMASV 293
           +P    + SCG    +K+W    GK+G+   V ++     H+ +V S  +S     ++S 
Sbjct: 278 NPTGTLLASCGSDKIIKIW----GKEGD-NWVCKSTLTDAHTRTVRSLGWSPCGNYLSSA 114

Query: 294 SKDGTWKLW 302
           S D T  +W
Sbjct: 113 SFDATTAVW 87
>25930
          Length = 419

 Score = 33.1 bits (74), Expect = 0.20,   Method: Composition-based stats.
 Identities = 16/45 (35%), Positives = 26/45 (57%)
 Frame = +1

Query: 273 GHSASVHSFAFSNDSRRMASVSKDGTWKLWDTDVEYKKQQDPYLL 317
           G   S+ +  +S D+ R+ SVS+ GT ++WD +     +QD  LL
Sbjct: 190 GQDDSIKNLNWSLDATRLISVSESGTLQVWDLEGPAVNKQDARLL 324
>00825
          Length = 1821

 Score = 33.1 bits (74), Expect = 0.20,   Method: Compositional matrix adjust.
 Identities = 12/37 (32%), Positives = 23/37 (62%)
 Frame = -2

Query: 78   LAAALKSHSGNISCMDFSSNGKYLATCADDRTVRIWS 114
            +A  +++H G +  M   S+G+Y  +C  D+T++ WS
Sbjct: 1769 MACRVQAHDGIVHGMAAHSSGQYFFSCGSDKTIKQWS 1659
>14500
          Length = 1238

 Score = 33.1 bits (74), Expect = 0.24,   Method: Compositional matrix adjust.
 Identities = 28/115 (24%), Positives = 49/115 (42%), Gaps = 2/115 (1%)
 Frame = +3

Query: 202 ASSDTTVLIWNLK-GQVLSTINTNQMNNSHAVISPCSRFVGSCGFTPD-VKVWEVCFGKK 259
            ++D  +  WN   G  LS+++T     +          + S GF  + + +W+      
Sbjct: 264 GTADRHIHFWNCNTGTNLSSVDTKSQVCALLWSKEHRELISSHGFAQNQLIIWK------ 425

Query: 260 GEFQEVLRAFELKGHSASVHSFAFSNDSRRMASVSKDGTWKLWDTDVEYKKQQDP 314
             +  + R  EL GH+A V   A S D   + S + D T +LW      K+++ P
Sbjct: 426 --YPAMSRVAELTGHTARVLHMAMSPDGETVVSAAADETLRLWKCFTVDKEKKRP 584

 Score = 30.0 bits (66), Expect = 2.1,   Method: Compositional matrix adjust.
 Identities = 12/37 (32%), Positives = 21/37 (56%)
 Frame = +2

Query: 80  AALKSHSGNISCMDFSSNGKYLATCADDRTVRIWSTK 116
             L  HS  +  + +S +GKYLA+ A+D  + +W  +
Sbjct: 41  GTLSGHSQEVCGLRWSPDGKYLASGANDNLLCVWPAQ 151
>15118
          Length = 1074

 Score = 32.0 bits (71), Expect = 0.56,   Method: Compositional matrix adjust.
 Identities = 14/34 (41%), Positives = 21/34 (61%)
 Frame = +3

Query: 81  ALKSHSGNISCMDFSSNGKYLATCADDRTVRIWS 114
               HS +I+ + FS +G++L T + D TVR WS
Sbjct: 438 VFSGHSNSITDLSFSGDGRWLITASMDCTVRTWS 539
>30295
          Length = 593

 Score = 31.6 bits (70), Expect = 0.63,   Method: Compositional matrix adjust.
 Identities = 24/91 (26%), Positives = 37/91 (40%), Gaps = 3/91 (3%)
 Frame = +2

Query: 271 LKGHSASVHSFAFSNDSRRMASVSKDGTWKLWDTDVEYKKQQDPYLLRTGRFEEASTMPC 330
           L+ H A +++  ++ DSR + S S+DG   +WD     K    P          +  M C
Sbjct: 233 LRXHLAKIYAMHWATDSRNLVSASQDGKLIVWDGYTTNKVHAIP-------LRSSWVMTC 391

Query: 331 RLALSPDTHVLALATGTN---IHLFNTRRGE 358
             A +P    +A     N   I+   TR G 
Sbjct: 392 --AYAPSGGYVACGGLDNICSIYSLKTREGN 478
>01768
          Length = 1424

 Score = 31.6 bits (70), Expect = 0.65,   Method: Compositional matrix adjust.
 Identities = 27/139 (19%), Positives = 66/139 (47%), Gaps = 5/139 (3%)
 Frame = +3

Query: 80  AALKSHSGNISCMDFSSN-GKYLATCADDRTVRIWSTKDFLQREHRSMRANVELDHA--- 135
           ++  +H+ ++  + +S N G   A+C+ DRT+RIW+T+   Q+  ++    V   H+   
Sbjct: 819 SSYAAHTDSVEDVQWSPNEGNVFASCSVDRTLRIWNTQ---QKPSKANVLTVPEAHSRDI 989

Query: 136 TLVRFSPDCRAFIVWLANGDTLRVFKMTKREDGGFTFTATPEDFPKKHKAPIINIGIADT 195
            ++ ++P  +  +    +   ++++ +    +   +  A+   F K H  P+ ++     
Sbjct: 990 NVINWNPIEKHLLASGGDDGIIKIWDLRMFRNKPVSAQAS---F-KLHSQPVTSLEWNPQ 1157

Query: 196 GKFIMTASS-DTTVLIWNL 213
              ++ AS  D  + IW+ 
Sbjct: 1158DSSVLAASGEDDQITIWDF 1214
>31384
          Length = 474

 Score = 31.6 bits (70), Expect = 0.68,   Method: Compositional matrix adjust.
 Identities = 11/33 (33%), Positives = 20/33 (60%)
 Frame = -1

Query: 181 KKHKAPIINIGIADTGKFIMTASSDTTVLIWNL 213
           + H  P++++  +D G  + TAS D T  +W+L
Sbjct: 144 QTHTGPVLDVDWSDDGTKVFTASCDKTAKVWDL 46
>19140
          Length = 573

 Score = 31.6 bits (70), Expect = 0.72,   Method: Compositional matrix adjust.
 Identities = 13/36 (36%), Positives = 21/36 (58%)
 Frame = -3

Query: 267 RAFELKGHSASVHSFAFSNDSRRMASVSKDGTWKLW 302
           +  +LKGH+ +V +   + D  +  S S DGT +LW
Sbjct: 511 KLMKLKGHTDNVKALVLNRDGTQCLSGSSDGTIRLW 404
>13278
          Length = 870

 Score = 31.2 bits (69), Expect = 0.78,   Method: Compositional matrix adjust.
 Identities = 11/33 (33%), Positives = 21/33 (63%)
 Frame = +1

Query: 182 KHKAPIINIGIADTGKFIMTASSDTTVLIWNLK 214
           KH+ P+ ++  +  GK++ + S D  V IWN++
Sbjct: 196 KHQEPVYSVAFSPDGKYLASGSFDKCVHIWNVQ 294

 Score = 30.4 bits (67), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 21/67 (31%), Positives = 30/67 (44%)
 Frame = +1

Query: 237 SRFVGSCGFTPDVKVWEVCFGKKGEFQEVLRAFELKGHSASVHSFAFSNDSRRMASVSKD 296
           S  + S  F   V++WEV        +  L    L  H   V+S AFS D + +AS S D
Sbjct: 112 SLILASASFDSTVRLWEV--------ERGLCLHTLTKHQEPVYSVAFSPDGKYLASGSFD 267

Query: 297 GTWKLWD 303
               +W+
Sbjct: 268 KCVHIWN 288

 Score = 29.6 bits (65), Expect = 2.3,   Method: Compositional matrix adjust.
 Identities = 14/40 (35%), Positives = 22/40 (55%)
 Frame = +1

Query: 77  LLAAALKSHSGNISCMDFSSNGKYLATCADDRTVRIWSTK 116
           L    L  H   +  + FS +GKYLA+ + D+ V IW+ +
Sbjct: 175 LCLHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNVQ 294
>26939
          Length = 388

 Score = 31.2 bits (69), Expect = 0.89,   Method: Composition-based stats.
 Identities = 17/59 (28%), Positives = 31/59 (52%), Gaps = 1/59 (1%)
 Frame = +2

Query: 196 GKFIMTASSDTTVLIWNLKGQ-VLSTINTNQMNNSHAVISPCSRFVGSCGFTPDVKVWE 253
           GK++++AS D T+ +W+L+ +  + T+  +Q   +         +V S      VKVWE
Sbjct: 2   GKYLVSASDDKTIRVWDLRNKRCMKTLYAHQHFCTSIDFHKAHPYVISGSVDQTVKVWE 178

 Score = 30.0 bits (66), Expect = 1.9,   Method: Composition-based stats.
 Identities = 9/20 (45%), Positives = 16/20 (80%)
 Frame = +2

Query: 98  GKYLATCADDRTVRIWSTKD 117
           GKYL + +DD+T+R+W  ++
Sbjct: 2   GKYLVSASDDKTIRVWDLRN 61
>12574
          Length = 521

 Score = 30.8 bits (68), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 19/71 (26%), Positives = 34/71 (47%)
 Frame = +3

Query: 233 ISPCSRFVGSCGFTPDVKVWEVCFGKKGEFQEVLRAFELKGHSASVHSFAFSNDSRRMAS 292
            SP   ++ S      +K+W       G+F++ +      GH   +   A+S+DS+ + S
Sbjct: 210 FSPNGDWLASSSADKLIKIWGA---YDGKFEKTIA-----GHKLGLSDVAWSSDSKLLCS 365

Query: 293 VSKDGTWKLWD 303
            S D T K+W+
Sbjct: 366 ASDDKTLKIWE 398

 Score = 27.7 bits (60), Expect = 9.3,   Method: Compositional matrix adjust.
 Identities = 11/32 (34%), Positives = 21/32 (65%)
 Frame = +3

Query: 82  LKSHSGNISCMDFSSNGKYLATCADDRTVRIW 113
           +  H   +S + +SS+ K L + +DD+T++IW
Sbjct: 300 IAGHKLGLSDVAWSSDSKLLCSASDDKTLKIW 395
>37180
          Length = 681

 Score = 30.4 bits (67), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 19/59 (32%), Positives = 29/59 (49%)
 Frame = +1

Query: 77  LLAAALKSHSGNISCMDFSSNGKYLATCADDRTVRIWSTKDFLQREHRSMRANVELDHA 135
           LL    + H+  ++   F+S G  + + +DDRTVR+W       R  RS  A +  D A
Sbjct: 121 LLVNVFQGHTQPVTSAVFAS-GDKVVSGSDDRTVRVWD-----MRNMRSPIATIRTDSA 279
>03395
          Length = 2795

 Score = 30.4 bits (67), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 29/128 (22%), Positives = 51/128 (39%), Gaps = 6/128 (4%)
 Frame = +2

Query: 181 KKHKAPIINIGIADTGKFIMTASSDTTVLIWNLKGQVLSTINTNQMNNSHAVISPCSRFV 240
           K+HK  +  I I    +  ++AS+D + +IW+L        NT         +  C  F 
Sbjct: 137 KEHKGKVTAIQIHTNDRCCVSASTDGSTIIWDL------ITNTRSQIVLANTLFKCVCFG 298

Query: 241 G------SCGFTPDVKVWEVCFGKKGEFQEVLRAFELKGHSASVHSFAFSNDSRRMASVS 294
           G      + G    +  WEV  G       +LR  E    + ++++     D + + +  
Sbjct: 299 GKDLHILTSGTDHKIGYWEVGDGG------LLRELE-GSQTGAINTIDIDRDGQTILTGG 457

Query: 295 KDGTWKLW 302
           +D   KLW
Sbjct: 458 EDSLLKLW 481

 Score = 28.1 bits (61), Expect = 8.2,   Method: Compositional matrix adjust.
 Identities = 37/170 (21%), Positives = 62/170 (36%), Gaps = 3/170 (1%)
 Frame = +2

Query: 233 ISPCSRFVGSCGFTPDVKVWEVCFGK-KGEFQEVLRAFELKGHSASVHSFAFSNDSRRMA 291
           ++ C   + S G    V+VW++      G+ +  L A  +K H   V +     + R   
Sbjct: 20  VTSCGTKLVSGGGEGQVRVWDIVKDMLTGKTRGDLVA-NMKEHKGKVTAIQIHTNDRCCV 196

Query: 292 SVSKDGTWKLWDTDVEYKKQQDPYLLRTGRFEEASTM-PCRLALSPDTHVLALATGTNIH 350
           S S DG+  +WD     + Q             A+T+  C      D H+L   T   I 
Sbjct: 197 SASTDGSTIIWDLITNTRSQ----------IVLANTLFKCVCFGGKDLHILTSGTDHKIG 346

Query: 351 LFNTRRGEKEEYFECVHGECIADLTFDITGRFLASCG-DRAVRLFHNTPG 399
            +    G      E      I  +  D  G+ + + G D  ++L+    G
Sbjct: 347 YWEVGDGGLLRELEGSQTGAINTIDIDRDGQTILTGGEDSLLKLWRYNEG 496
>34511
          Length = 1037

 Score = 30.0 bits (66), Expect = 1.9,   Method: Compositional matrix adjust.
 Identities = 15/54 (27%), Positives = 26/54 (48%)
 Frame = +3

Query: 79  AAALKSHSGNISCMDFSSNGKYLATCADDRTVRIWSTKDFLQREHRSMRANVEL 132
           +  L  H   +SC+  + NG  +AT + D  +R+W+      R +   R NV +
Sbjct: 51  SGILAGHDNRVSCLGVTENGMSVATGSWDSFLRVWN*VSCTMRINGWGRVNVAV 212
>07151
          Length = 512

 Score = 30.0 bits (66), Expect = 2.0,   Method: Compositional matrix adjust.
 Identities = 12/35 (34%), Positives = 19/35 (54%)
 Frame = -1

Query: 80  AALKSHSGNISCMDFSSNGKYLATCADDRTVRIWS 114
           A  K + G + C DFS +   + T   DR +R+W+
Sbjct: 179 AVFKVYKG-VKCFDFSKDKNIIVTGGMDRIIRLWN 78
>29912
          Length = 510

 Score = 29.6 bits (65), Expect = 2.4,   Method: Compositional matrix adjust.
 Identities = 12/32 (37%), Positives = 20/32 (62%)
 Frame = +3

Query: 82  LKSHSGNISCMDFSSNGKYLATCADDRTVRIW 113
           L  HS  +  + +S +GKYLA+ A+D  + +W
Sbjct: 246 LSGHSQEVCGLRWSPDGKYLASGANDNLLCVW 341
>19571
          Length = 457

 Score = 29.6 bits (65), Expect = 2.6,   Method: Compositional matrix adjust.
 Identities = 14/40 (35%), Positives = 20/40 (50%)
 Frame = +2

Query: 79  AAALKSHSGNISCMDFSSNGKYLATCADDRTVRIWSTKDF 118
           AAAL +   N+ C   S +G+Y+    D    R  +T DF
Sbjct: 254 AAALHAPQSNLQCQTLSRDGQYMIVSGDAGVWRCGATHDF 373
>17298
          Length = 476

 Score = 29.6 bits (65), Expect = 2.6,   Method: Compositional matrix adjust.
 Identities = 16/54 (29%), Positives = 28/54 (51%)
 Frame = -1

Query: 83  KSHSGNISCMDFSSNGKYLATCADDRTVRIWSTKDFLQREHRSMRANVELDHAT 136
           + H+G ++C+ F+     + + + D TVR W T+    R H  ++    LD AT
Sbjct: 221 RDHAGTVNCVKFNEESTVILSGSLDNTVRAWDTR---SRSHTPIQV---LDEAT 78
>27525
          Length = 828

 Score = 29.3 bits (64), Expect = 3.1,   Method: Compositional matrix adjust.
 Identities = 14/49 (28%), Positives = 28/49 (57%)
 Frame = +2

Query: 79  AAALKSHSGNISCMDFSSNGKYLATCADDRTVRIWSTKDFLQREHRSMR 127
           +AAL+ +S  I  +D+SS+ +YL     D  +  W  ++  ++  R++R
Sbjct: 188 SAALRYNSTFIMHLDWSSDCRYLQCTLGDYELVFWEVQNMKKQSGRALR 334
>15745
          Length = 1183

 Score = 28.9 bits (63), Expect = 3.9,   Method: Compositional matrix adjust.
 Identities = 13/35 (37%), Positives = 22/35 (62%), Gaps = 1/35 (2%)
 Frame = +2

Query: 84  SHSGNISCMDFSSNGKY-LATCADDRTVRIWSTKD 117
           +H   +  +DF+ N +Y LA+C DD  V+ W T++
Sbjct: 704 AHGQLVRDLDFNPNRQYYLASCGDDCRVKFWDTRN 808
>14555
          Length = 627

 Score = 28.9 bits (63), Expect = 4.2,   Method: Compositional matrix adjust.
 Identities = 13/36 (36%), Positives = 20/36 (55%)
 Frame = -3

Query: 79  AAALKSHSGNISCMDFSSNGKYLATCADDRTVRIWS 114
           +  L  H   +SC+  S +G  L T + D T+RIW+
Sbjct: 361 STILYGHDNRVSCLRISPDGTSLCTGSWDYTLRIWA 254

 Score = 28.5 bits (62), Expect = 5.3,   Method: Compositional matrix adjust.
 Identities = 11/35 (31%), Positives = 20/35 (57%)
 Frame = -2

Query: 82  LKSHSGNISCMDFSSNGKYLATCADDRTVRIWSTK 116
            + H  +I+C+ F  +G   AT +DD T R++  +
Sbjct: 611 FEGHEADINCVRFYPSGDAFATGSDDATCRLFDLR 507
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|61098124|ref|NP_080896.2| family with sequence
similarity 98, member B [Mus musculus]
         (429 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

28114                                                                 126   2e-29
>28114
          Length = 845

 Score =  126 bits (316), Expect = 2e-29,   Method: Compositional matrix adjust.
 Identities = 66/138 (47%), Positives = 96/138 (69%)
 Frame = +1

Query: 170 LLSQVESKVKDILCRVQKNHVGKPLLKVDLSSEQAEKLERINDALSCEYECRRRMLMKRL 229
           L S++E+KVK+++ +      GK LLK  LS +Q + +  +N A++ EY  RR ML+KRL
Sbjct: 409 LFSKLEAKVKELMGQ-HPGQTGKSLLKARLSDKQWDHVMDVNAAMAQEYRIRREMLLKRL 585

Query: 230 DVTVQSFGWSDRAKAKTDNIARIYQPKRYALSPKTTVTLAHLLAAREDLSKIIRTSSGIS 289
           DVT+QSF WSD+AK   D I ++YQP R  L  +T + +  +LAAREDL++I +TS+G S
Sbjct: 586 DVTIQSFMWSDKAKRXQDKINQVYQPIRKELLVQTRIGIPEILAAREDLTRIQKTSTGES 765

Query: 290 REKTACAINKVLMGRVPD 307
           R++  C INKV++GRV D
Sbjct: 766 RKE--CKINKVMIGRVSD 813

 Score = 62.0 bits (149), Expect = 5e-10,   Method: Compositional matrix adjust.
 Identities = 32/88 (36%), Positives = 50/88 (56%), Gaps = 1/88 (1%)
 Frame = +3

Query: 48  FSELCIWLGSQIKSLCNLEESITS-AGRDDLESFQLEISGFLKEMACPYSVLVSGDIKER 106
           F++L  WL  Q+  L  +EE + + +G DD+ +F LE+SGFL+E  C Y  L  G + ER
Sbjct: 12  FTQLVEWLVQQLADLTGVEERVHAISGPDDVSNFLLELSGFLREYGCVYPDLTQGPVNER 191

Query: 107 XXXXXXXXXXXXXXSTELQALQILQKKK 134
                         ++ELQA++++ KKK
Sbjct: 192 LDTSGKRLMLLDYLTSELQAVRMIGKKK 275
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|85719320|ref|NP_084156.2| prostaglandin reductase 2
[Mus musculus]
         (351 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

00104                                                                 125   2e-29
02616                                                                  59   3e-09
08664                                                                  29   2.7  
02119                                                                  27   10.0 
>00104
          Length = 1480

 Score =  125 bits (315), Expect = 2e-29,   Method: Compositional matrix adjust.
 Identities = 71/172 (41%), Positives = 102/172 (59%), Gaps = 1/172 (0%)
 Frame = -2

Query: 173  QIGHLLGCSRVVGICGTQEKCLFLTSELGFDAAVNYKTGNVAEQLREACPGGVDVYFDNV 232
            QI  + GC+ V+G  G+Q KC +L  ELGFD   NYK   V E L++  P G+D++FDNV
Sbjct: 1479 QIAKVKGCT-VIGSAGSQAKCDWL-KELGFDHVFNYKETTVDEALKKFAPNGIDIHFDNV 1306

Query: 233  GGDISNAVIS-QMNENSHIILCGQISQYSNDVXXXXXXXXAVEAIRKERNITRERFTVLN 291
            GG+ S  V+S  +   + +++CG ISQY+N           V  I K+ ++      V+ 
Sbjct: 1305 GGEFSYTVMSNHLKFGARVVVCGAISQYNNTEDKEPSIFKFV--IYKQLDVLG--VIVVA 1138

Query: 292  YKDKFEPGILQLSQWFKEGKLKVKETMAKGLENMGVAFQSMMTGGNVGKQIV 343
            +KD+F   + QL QW KEGKLK +ET+ +G E+M  AF S+  G N GK +V
Sbjct: 1137 FKDRFPEALTQLMQWVKEGKLKYRETVTEGFEHMPEAFISLFKGANTGKAVV 982
>02616
          Length = 1048

 Score = 58.9 bits (141), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 41/170 (24%), Positives = 80/170 (47%), Gaps = 8/170 (4%)
 Frame = +1

Query: 182 RVVGICGTQEKCLFLTSELGFDAAVNYKTGNVAEQLREACPGGVDVYFDNVGGDISNAVI 241
            V+G C T +K  FL S +G D  +NYK  ++   L+   P GV+V +++VGG I +  +
Sbjct: 4   EVIGTCSTDDKVQFLKS-IGCDRPINYKKEDLGTVLKAEYPNGVNVVYESVGGAIFDTCL 180

Query: 242 SQMNENSHIILCGQISQYSNDVXXXXXXXXAVEAIRKERNITRERFTVLNYKDKFEPGIL 301
           + +     +++ G IS Y++D          +     + + +   F ++++   F   + 
Sbjct: 181 NNLAIGGRLMVIGAISGYTSDYSGFKASSM-LPLTXLQLSASVRGFFLMHFVRDFAEYMT 357

Query: 302 QLSQWFKEGKLKVKETMAK--------GLENMGVAFQSMMTGGNVGKQIV 343
           +L   +++GK+     M +        GL  +  A   M +  N+GK +V
Sbjct: 358 KLVGLYQQGKVTTAIDMGEKSPDGPFVGLNKVNSAVDYMFSSQNIGKIVV 507
>08664
          Length = 1295

 Score = 29.3 bits (64), Expect = 2.7,   Method: Compositional matrix adjust.
 Identities = 12/34 (35%), Positives = 19/34 (55%)
 Frame = +2

Query: 215 EQLREACPGGVDVYFDNVGGDISNAVISQMNENS 248
           E+L + CP GVD   D++ GD +     +M + S
Sbjct: 287 ERLLKECPSGVDFSVDDLKGDFNPKAYDRMMKKS 388
>02119
          Length = 1046

 Score = 27.3 bits (59), Expect = 10.0,   Method: Compositional matrix adjust.
 Identities = 26/81 (32%), Positives = 36/81 (44%), Gaps = 6/81 (7%)
 Frame = -3

Query: 3   IQRVVLNSRPGKNGNPVAENFRVEEFSLPDALNEGQVQVRTLYLSVDPYMRCKMNEDTGT 62
           +  V++N  P K G P  E F  E+  + D+LNE    V  L+ S++     K NE  G 
Sbjct: 708 VMDVIVN--PPKPGEPSYELFCQEKKIVLDSLNEKAKLVTQLFNSIE---GIKCNEVQGA 544

Query: 63  DY------LAPWQLAQVADGG 77
            Y      L P  +A   D G
Sbjct: 543 MYAFPNITLPPKAIAAAKDDG 481
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|161760627|ref|NP_031690.3| cadherin 2 [Mus musculus]
         (906 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

36752                                                                  88   3e-29
29160                                                                  81   2e-15
35151                                                                  79   8e-15
25641                                                                  78   1e-14
18971                                                                  65   4e-14
37991                                                                  62   1e-13
34098                                                                  46   3e-13
08409                                                                  73   6e-13
29507                                                                  67   4e-11
19661                                                                  60   5e-09
14391                                                                  55   9e-08
17709                                                                  55   2e-07
18709                                                                  51   2e-06
18019                                                                  50   4e-06
01558                                                                  49   8e-06
13573                                                                  49   1e-05
08534                                                                  48   2e-05
14946                                                                  48   2e-05
12240                                                                  45   2e-04
14137                                                                  43   7e-04
33808                                                                  42   0.001
18725                                                                  39   0.006
29492                                                                  39   0.009
19334                                                                  38   0.014
38442                                                                  33   0.63 
27585                                                                  32   0.90 
18690                                                                  32   1.2  
29111                                                                  31   2.6  
00918                                                                  31   2.8  
24587                                                                  30   4.1  
15121                                                                  30   4.4  
12703                                                                  30   4.9  
>36752
          Length = 1243

 Score = 88.2 bits (217), Expect(2) = 3e-29,   Method: Compositional matrix adjust.
 Identities = 80/255 (31%), Positives = 118/255 (46%), Gaps = 6/255 (2%)
 Frame = +3

Query: 185 SDRD----KNLSLRYSVTGPGADQPPTGIFIINPISGQLSVTKPLDRELIARFHLRAHAV 240
           SDRD    +N  + Y++ G GAD      F++   SG L     LDRE   R+HL   A 
Sbjct: 18  SDRDEASTQNARITYTLDGQGADH-----FMLEKDSGILRTAAALDRETQQRYHLEVTAT 182

Query: 241 DINGNQXXXXXXXXXXXXXXXXXRPEFLHQVWNG-SVPEGSKPGTYVMTVTAIDADDPNA 299
           D  G                    PEF   + +  +V E ++  T +  VT +D D    
Sbjct: 183 D--GGGLSCVTEVQIFLRDVNDXPPEFTDSLRDTLTVQEDARVNTLLTRVTTVDKD--TG 350

Query: 300 LNGMLRYRILSQAPSTPSPNMFTINNETGDIITVAAGLDREKVQQYTLIIQATDMEGNPT 359
           +N   RY ++ + PS     +F+I  ++G I+++   LDRE+  QY + I A + E +P 
Sbjct: 351 INRNTRYELMQREPS-----VFSIEPKSG-ILSLVGSLDREEHPQYDVTIVAYN-EISP- 506

Query: 360 YGLSNTATAVITVTDVNDNPPEFTAMTFYGEVPENR-VDVIVANLTVTDKDQPHTPAWNA 418
             LS T    + V DVNDNPP F   ++Y  V E+  V  +V  +  T  D     A   
Sbjct: 507 -ALSATTVLKVVVLDVNDNPPTFERTSYYAAVAEDAGVGTVVGRVRATSLDIGANAAIT- 680

Query: 419 AYRISGGDPTGRFAI 433
            Y I+ G+  G+F I
Sbjct: 681 -YSIAAGNQQGKFVI 722

 Score = 59.7 bits (143), Expect(2) = 3e-29,   Method: Compositional matrix adjust.
 Identities = 54/173 (31%), Positives = 80/173 (46%), Gaps = 10/173 (5%)
 Frame = +1

Query: 441 DGLVTVVKPIDFETNRMFVLTVAAENQVPLAKGIQHPPQS-TATVSVTVIDVNENP-YFA 498
           +G + V +P+D E +R + LT+       LA+    PP S TA +S+ + D+N+NP  F+
Sbjct: 733 NGEIKVSEPLDHEVSREYFLTI-------LARDHGSPPLSNTAIISINITDINDNPPRFS 891

Query: 499 PNPKIIRQEEGLHAGTMLTTLTAQDPDRYMQQNIRYT--------KLSDPANWLKIDPVN 550
            +       E +  GT +  + A D D Y    I Y+        +LSD   W+  D   
Sbjct: 892 QDTYATTVSEVVLVGTEVFKVMATDADSYANSVITYSIIDGNPVRQLSD---WVLRD--- 1053

Query: 551 GQITTIAVLDRESPNVKNNIYNATFLASDNGIPPMSGTGTLQIYLLDINDNAP 603
           G I     LDRES       Y  T  A D+G P +  T  + + + D NDN P
Sbjct: 1054GIIQVAKHLDRESVER----YALTIQARDSGQPMLYSTAVVSVRVEDANDNPP 1200

 Score = 68.2 bits (165), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 64/172 (37%), Positives = 84/172 (48%), Gaps = 2/172 (1%)
 Frame = +1

Query: 331 ITVAAGLDREKVQQYTLIIQATDMEGNPTYGLSNTATAVITVTDVNDNPPEFTAMTFYGE 390
           I V+  LD E  ++Y L I A D  G+P   LSNTA   I +TD+NDNPP F+  T+   
Sbjct: 742 IKVSEPLDHEVSREYFLTILARD-HGSPP--LSNTAIISINITDINDNPPRFSQDTYATT 912

Query: 391 VPE-NRVDVIVANLTVTDKDQPHTPAWNAAYRISGGDPTGRFAILTDPNSNDGLVTVVKP 449
           V E   V   V  +  TD D          Y I  G+P  +   L+D    DG++ V K 
Sbjct: 913 VSEVVLVGTEVFKVMATDADSYANSV--ITYSIIDGNPVRQ---LSDWVLRDGIIQVAKH 1077

Query: 450 IDFETNRMFVLTVAAENQVPLAKGIQHPPQSTATVSVTVIDVNEN-PYFAPN 500
           +D E+   + LT+ A +        Q    STA VSV V D N+N P FA N
Sbjct: 1078LDRESVERYALTIQARDSG------QPMLYSTAVVSVRVEDANDNPPLFASN 1215

 Score = 63.9 bits (154), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 56/176 (31%), Positives = 76/176 (43%)
 Frame = +1

Query: 217 GQLSVTKPLDRELIARFHLRAHAVDINGNQXXXXXXXXXXXXXXXXXRPEFLHQVWNGSV 276
           G++ V++PLD E+   + L   A D                       P F    +  +V
Sbjct: 736 GEIKVSEPLDHEVSREYFLTILARDHGSPPLSNTAIISINITDINDNPPRFSQDTYATTV 915

Query: 277 PEGSKPGTYVMTVTAIDADDPNALNGMLRYRILSQAPSTPSPNMFTINNETGDIITVAAG 336
            E    GT V  V A DAD  +  N ++ Y I+   P     +    +     II VA  
Sbjct: 916 SEVVLVGTEVFKVMATDAD--SYANSVITYSIIDGNPVRQLSDWVLRDG----IIQVAKH 1077

Query: 337 LDREKVQQYTLIIQATDMEGNPTYGLSNTATAVITVTDVNDNPPEFTAMTFYGEVP 392
           LDRE V++Y L IQA D  G P   L +TA   + V D NDNPP F + T   +VP
Sbjct: 1078LDRESVERYALTIQARD-SGQPM--LYSTAVVSVRVEDANDNPPLFASNTTPHQVP 1236

 Score = 58.5 bits (140), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 51/200 (25%), Positives = 93/200 (46%), Gaps = 2/200 (1%)
 Frame = +3

Query: 406 TDKDQPHTPAWNAAYRISGGDPTGRFAILTDPNSNDGLVTVVKPIDFETNRMFVLTVAAE 465
           +D+D+  T      Y + G    G    + + +S  G++     +D ET + + L V A 
Sbjct: 18  SDRDEASTQNARITYTLDG---QGADHFMLEKDS--GILRTAAALDRETQQRYHLEVTAT 182

Query: 466 NQVPLAKGIQHPPQSTATVSVTVIDVNENP-YFAPNPK-IIRQEEGLHAGTMLTTLTAQD 523
           +   L+            V + + DVN+ P  F  + +  +  +E     T+LT +T  D
Sbjct: 183 DGGGLS--------CVTEVQIFLRDVNDXPPEFTDSLRDTLTVQEDARVNTLLTRVTTVD 338

Query: 524 PDRYMQQNIRYTKLSDPANWLKIDPVNGQITTIAVLDRESPNVKNNIYNATFLASDNGIP 583
            D  + +N RY  +    +   I+P +G ++ +  LDRE    ++  Y+ T +A +   P
Sbjct: 339 KDTGINRNTRYELMQREPSVFSIEPKSGILSLVGSLDRE----EHPQYDVTIVAYNEISP 506

Query: 584 PMSGTGTLQIYLLDINDNAP 603
            +S T  L++ +LD+NDN P
Sbjct: 507 ALSATTVLKVVVLDVNDNPP 566

 Score = 40.4 bits (93), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 43/162 (26%), Positives = 65/162 (40%), Gaps = 5/162 (3%)
 Frame = +1

Query: 550 NGQITTIAVLDRESPNVKNNIYNATFLASDNGIPPMSGTGTLQIYLLDINDNAPQVLPQE 609
           NG+I     LD E     +  Y  T LA D+G PP+S T  + I + DINDN P+   Q+
Sbjct: 733 NGEIKVSEPLDHE----VSREYFLTILARDHGSPPLSNTAIISINITDINDNPPR-FSQD 897

Query: 610 AETCETPE-----PNSINITALDYDIDPNAGPFAFDLPLSPVTIKRNWTINRLNGDFAQL 664
                  E          + A D D   N+      +  +PV    +W    L     Q+
Sbjct: 898 TYATTVSEVVLVGTEVFKVMATDADSYANSVITYSIIDGNPVRQLSDWV---LRDGIIQV 1068

Query: 665 NLKIKFLEAGIYEVPIIITDSGNPPKSNISILRVKVCQCDSN 706
              +       Y + I   DSG P   + +++ V+V   + N
Sbjct: 1069AKHLDRESVERYALTIQARDSGQPMLYSTAVVSVRVEDANDN 1194
>29160
          Length = 1022

 Score = 80.9 bits (198), Expect = 2e-15,   Method: Compositional matrix adjust.
 Identities = 69/211 (32%), Positives = 98/211 (46%), Gaps = 5/211 (2%)
 Frame = -2

Query: 440 NDGLVTVVKPIDFE--TNRMFVLTVAAENQVPLAKGIQHPPQSTATVSVTVIDVNEN-PY 496
           N G + V   +D+E  + + F LTV AE+  P     +H   +TA V++ V D N+N P 
Sbjct: 985 NMGSILVYNEVDYEQASRQFFNLTVIAEDPNP-----RH--TATAYVAIXVRDFNDNAPA 827

Query: 497 FAPNPKIIRQEEGLHAGTMLTTLTAQDPDRYMQQNIRYT--KLSDPANWLKIDPVNGQIT 554
             P    +R  E   AG  + T  A D D        ++  + +DP     I P  G++T
Sbjct: 826 IKPQVITVRIFEDEPAGFHVATFNATDMDSGDNAKFEFSIDRHTDPRRHFSIHPETGRVT 647

Query: 555 TIAVLDRESPNVKNNIYNATFLASDNGIPPMSGTGTLQIYLLDINDNAPQVLPQEAETCE 614
               LDRE+     + +  T  A D G PPM+G GTL +++ DINDN PQ L        
Sbjct: 646 LRRPLDRET----QDHHVITIRAIDKGDPPMTGYGTLTVFVKDINDNFPQFLENYQPQVL 479

Query: 615 TPEPNSINITALDYDIDPNAGPFAFDLPLSP 645
             E N   +    +  DP+A PF   L L P
Sbjct: 478 ERENNFPAVLQQIFAKDPDASPFGPPLALLP 386

 Score = 40.8 bits (94), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 35/113 (30%), Positives = 53/113 (46%)
 Frame = -2

Query: 270 QVWNGSVPEGSKPGTYVMTVTAIDADDPNALNGMLRYRILSQAPSTPSPNMFTINNETGD 329
           QV    + E    G +V T  A D D  +  N    + I      T     F+I+ ETG 
Sbjct: 817 QVITVRIFEDEPAGFHVATFNATDMDSGD--NAKFEFSIDRH---TDPRRHFSIHPETGR 653

Query: 330 IITVAAGLDREKVQQYTLIIQATDMEGNPTYGLSNTATAVITVTDVNDNPPEF 382
           + T+   LDRE    + + I+A D +G+P   ++   T  + V D+NDN P+F
Sbjct: 652 V-TLRRPLDRETQDHHVITIRAID-KGDPP--MTGYGTLTVFVKDINDNFPQF 506

 Score = 29.6 bits (65), Expect = 6.0,   Method: Compositional matrix adjust.
 Identities = 19/56 (33%), Positives = 27/56 (48%), Gaps = 4/56 (7%)
 Frame = -1

Query: 553 ITTIAVLDRESPNVKNNIYNATFLASD----NGIPPMSGTGTLQIYLLDINDNAPQ 604
           I+T+   DRE    K   Y    +  D    N    M+GT TL + + D+NDN P+
Sbjct: 275 ISTLRSFDRE----KQKYYYIPIVMWDMRGKNSKQAMTGTNTLTVTIADVNDNVPK 120
>35151
          Length = 844

 Score = 79.0 bits (193), Expect = 8e-15,   Method: Compositional matrix adjust.
 Identities = 75/278 (26%), Positives = 136/278 (48%), Gaps = 19/278 (6%)
 Frame = +2

Query: 345 YTLIIQATDME--GNPTYGLSNTATAVIT--VTDVNDNPPEFTAMTFYGEVPENRVD--- 397
           Y + +QAT+++  G   +G + TA+A++T  VTDVNDN PEF+   ++ ++ EN +    
Sbjct: 5   YAMWVQATEIDVPGRQNFG-TTTASAIVTISVTDVNDNVPEFSQTNYHAQIQENMLKGVP 181

Query: 398 --VIVANLTVTDKDQPHTPAWNAAYRISGGDPTGRFAILTDPNSNDGLVTV----VKPID 451
              +   + V+DKDQ  T +  A      G P   F  L +    +  V +     + +D
Sbjct: 182 LTFLGGVMRVSDKDQG-TNSHFALTVEKNGQPYHDFTTLPEEVYTESTVLLRVNNSESLD 358

Query: 452 FETNRMFVLTVAAENQVPLAKGIQHPPQSTATVSVTVIDVNEN-PYFAPNPKIIRQEEGL 510
           +E  +  +  + A  +V  A+       STATV++ ++D+N+N P F  +  +    E  
Sbjct: 359 YEAEKEIIFQIVAR-EVDTAE----QRSSTATVTLNILDMNDNAPNFTHSQYLFTVAEDA 523

Query: 511 HAGTMLTTLTAQDPDRYMQQNIRYTKLSDPANWLKIDPVNGQITTIAVLDRESPNVKNNI 570
             G  +  + A D D     ++RY+   +  ++ ++D +NG +     LDRE+       
Sbjct: 524 SVGQSIGDIFASDDDTGSYGSVRYSIRGENRHF-RVDSLNGTMYVNNALDRETT------ 682

Query: 571 YNATFLASDNGIPPMSGTGT-----LQIYLLDINDNAP 603
            +  FL+++     + G GT     ++I + D+NDNAP
Sbjct: 683 -SRYFLSAE----AIDGGGTRAPTEIEIVVTDVNDNAP 781

 Score = 40.8 bits (94), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 57/231 (24%), Positives = 94/231 (40%), Gaps = 13/231 (5%)
 Frame = +2

Query: 176 FPQELVRIRSDRDKNLSLRYSVTGPGADQP-------PTGIFIINPISGQLSVTKPLD-- 226
           F   ++R+ SD+D+  +  +++T     QP       P  ++  + +  +++ ++ LD  
Sbjct: 188 FLGGVMRV-SDKDQGTNSHFALTVEKNGQPYHDFTTLPEEVYTESTVLLRVNNSESLDYE 364

Query: 227 --RELIARFHLRAHAVDINGNQXXXXXXXXXXXXXXXXXRPEFLHQVWNGSVPEGSKPGT 284
             +E+I  F + A  VD    Q                  P F H  +  +V E +  G 
Sbjct: 365 AEKEII--FQIVAREVD-TAEQRSSTATVTLNILDMNDNAPNFTHSQYLFTVAEDASVGQ 535

Query: 285 YVMTVTAIDADDPNALNGMLRYRILSQAPSTPSPNMFTINNETGDIITVAAGLDREKVQQ 344
            +  + A  +DD     G +RY I  +         F +++  G +  V   LDRE   +
Sbjct: 536 SIGDIFA--SDDDTGSYGSVRYSIRGE------NRHFRVDSLNGTMY-VNNALDRETTSR 688

Query: 345 YTLIIQATDMEGN--PTYGLSNTATAVITVTDVNDNPPEFTAMTFYGEVPE 393
           Y L  +A D  G   PT          I VTDVNDN P F    + G + E
Sbjct: 689 YFLSAEAIDGGGTRAPT-------EIEIVVTDVNDNAPLFRRSDYEGVIRE 820
>25641
          Length = 921

 Score = 78.2 bits (191), Expect = 1e-14,   Method: Compositional matrix adjust.
 Identities = 75/223 (33%), Positives = 106/223 (47%), Gaps = 25/223 (11%)
 Frame = +2

Query: 185 SDRDKNLSLRYSVTGPGADQPPTGIFIINPISGQLSVTKPLDRE-----------LIARF 233
           +DR  N+S  Y++ G G  +PP   F I+PI+G L V KPLDR+           ++AR 
Sbjct: 317 TDRPNNIS--YTLQGYGT-EPPNQYFRIDPITGGLFVIKPLDRDGPHGRSNYQFTVVARD 487

Query: 234 H-----------LRAHAVDINGNQXXXXXXXXXXXXXXXXXRPEFLHQVWNGSVPEGSKP 282
                       +     DIN N                  +P F      GSV E S+P
Sbjct: 488 EPHQPWQFGYATVEVLPADINDN------------------KPTFDATKLKGSVDEHSEP 613

Query: 283 GTYVMTVTAIDADDPNALNGMLRYRILSQAPSTPSP-NMFTINNETGDIITVA--AGLDR 339
           GT VM V A D D  N  NG + Y I+  + +  S  + F I+ ++G I T      LDR
Sbjct: 614 GTSVMFVLATDPDRGN--NGSVVYDIIKNSVTVGSKQDYFVIDRQSGLIKTNVDKRDLDR 787

Query: 340 EKVQQYTLIIQATDMEGNPTYGLSNTATAVITVTDVNDNPPEF 382
           E +  +TL ++A+D EG P   L+ TAT  I+++D+ND  P F
Sbjct: 788 ETIPSFTLEVRASD-EGKPP--LNTTATITISLSDINDQKPVF 907

 Score = 69.7 bits (169), Expect = 4e-12,   Method: Compositional matrix adjust.
 Identities = 80/305 (26%), Positives = 136/305 (44%), Gaps = 22/305 (7%)
 Frame = +2

Query: 422 ISGGDPTGRFAILTDPNSNDGLVTVVKPIDFET-NRMFVLTVAAENQVPLAKGIQHPPQS 480
           + G  P  +F I     S  G + V K +D+E+ +R F LT+ A + +  A         
Sbjct: 20  VDGNAPLYKFGI----KSATGGLFVAKTLDYESYDRFFELTLNASDGMHTA--------- 160

Query: 481 TATVSVTVIDVNEN-PYFAPNP-----KIIRQEEGLHAG-TMLTTLTAQDPDRYMQQNIR 533
           +  V VTV+D N+N P F   P     +I+ +++ +      L T+ A D D     NI 
Sbjct: 161 STRVQVTVLDANDNAPEFIDTPYRIENRIVEEDKSVTTRPKRLLTVLATDRDTDRPNNIS 340

Query: 534 YT----KLSDPANWLKIDPVNGQITTIAVLDRESPNVKNNIYNATFLASDNGIPPMS-GT 588
           YT        P  + +IDP+ G +  I  LDR+ P+ ++N Y  T +A D    P   G 
Sbjct: 341 YTLQGYGTEPPNQYFRIDPITGGLFVIKPLDRDGPHGRSN-YQFTVVARDEPHQPWQFGY 517

Query: 589 GTLQIYLLDINDNAP--QVLPQEAETCETPEPNSINITALDYDID-PNAGPFAFDLPLSP 645
            T+++   DINDN P       +    E  EP +  +  L  D D  N G   +D+  + 
Sbjct: 518 ATVEVLPADINDNKPTFDATKLKGSVDEHSEPGTSVMFVLATDPDRGNNGSVVYDIIKNS 697

Query: 646 VTIKRN---WTINRLNGDFAQLNLKIKFLEAGI---YEVPIIITDSGNPPKSNISILRVK 699
           VT+      + I+R +G   + N+  + L+      + + +  +D G PP +  + + + 
Sbjct: 698 VTVGSKQDYFVIDRQSG-LIKTNVDKRDLDRETIPSFTLEVRASDEGKPPLNTTATITIS 874

Query: 700 VCQCD 704
           +   +
Sbjct: 875 LSDIN 889

 Score = 65.5 bits (158), Expect = 9e-11,   Method: Compositional matrix adjust.
 Identities = 93/319 (29%), Positives = 132/319 (41%), Gaps = 31/319 (9%)
 Frame = +2

Query: 321 FTINNETGDIITVAAGLDREKVQQY-TLIIQATDMEGNPTYGLSNTATAV-ITVTDVNDN 378
           F I + TG +  VA  LD E   ++  L + A+D       G+   +T V +TV D NDN
Sbjct: 47  FGIKSATGGLF-VAKTLDYESYDRFFELTLNASD-------GMHTASTRVQVTVLDANDN 202

Query: 379 PPEFTAMTFYGEVPENRV---DVIVAN-----LTVTDKDQPHTPAWNAAYRISGGD---P 427
            PEF    +     ENR+   D  V       LTV   D+      N +Y + G     P
Sbjct: 203 APEFIDTPYR---IENRIVEEDKSVTTRPKRLLTVLATDRDTDRPNNISYTLQGYGTEPP 373

Query: 428 TGRFAILTDPNSNDGLVTVVKPIDFE-----TNRMFVLTVAAENQVPLAKGIQHPPQSTA 482
              F I  DP +  G + V+KP+D +     +N  F +    E   P   G        A
Sbjct: 374 NQYFRI--DPIT--GGLFVIKPLDRDGPHGRSNYQFTVVARDEPHQPWQFGY-------A 520

Query: 483 TVSVTVIDVNEN-PYFAPNPKIIRQEEGLHAGTMLTTLTAQDPDRYMQQNIRYTKLSDPA 541
           TV V   D+N+N P F         +E    GT +  + A DPDR    ++ Y       
Sbjct: 521 TVEVLPADINDNKPTFDATKLKGSVDEHSEPGTSVMFVLATDPDRGNNGSVVY------- 679

Query: 542 NWLKIDPVNGQITTIAVLDRESPNVKNNI------------YNATFLASDNGIPPMSGTG 589
           + +K     G      V+DR+S  +K N+            +     ASD G PP++ T 
Sbjct: 680 DIIKNSVTVGSKQDYFVIDRQSGLIKTNVDKRDLDRETIPSFTLEVRASDEGKPPLNTTA 859

Query: 590 TLQIYLLDINDNAPQVLPQ 608
           T+ I L DIND  P   P+
Sbjct: 860 TITISLSDINDQKPVFDPK 916
>18971
          Length = 787

 Score = 64.7 bits (156), Expect(2) = 4e-14,   Method: Compositional matrix adjust.
 Identities = 49/158 (31%), Positives = 79/158 (50%), Gaps = 7/158 (4%)
 Frame = -2

Query: 479 QSTATVSVTVIDVNE-NPYFAPNPKIIRQEEGLHAGTMLTTLTAQDPDRYMQQNIRYTKL 537
           +STATV +TV+DVN+ +P F  +   +R +E    GT +  + A+D D      I Y+  
Sbjct: 456 RSTATVILTVMDVNDISPSFKQDYYEVRVQENTAVGTSVGLVNAEDMDSNDNGRITYSLA 277

Query: 538 SDPANWLKIDPVNGQITTIA------VLDRESPNVKNNIYNATFLASDNGIPPMSGTGTL 591
            +    +  DP++  I           L+R+  +   + YN   LA D G P  +GT T+
Sbjct: 276 WEHPQKMYFDPMDFHIPLFVSPEGTLTLERQLDHEMTSEYNLLVLAVDGGDPARTGTATI 97

Query: 592 QIYLLDINDNAPQVLPQEAETCETPEPNSINITALDYD 629
            + + D+NDN PQ++         PEP++I+  AL  D
Sbjct: 96  TLLVEDVNDNPPQIV--------VPEPHNISAIALATD 7

 Score = 32.0 bits (71), Expect(2) = 4e-14,   Method: Compositional matrix adjust.
 Identities = 34/118 (28%), Positives = 45/118 (38%), Gaps = 1/118 (0%)
 Frame = -3

Query: 356 GNPTYGLSNTATAVITVTDVNDNPPEFTAMTFYGEVPENR-VDVIVANLTVTDKDQPHTP 414
           G+P+  L       + V D NDN P F    +Y  V EN  V V VA +   D D     
Sbjct: 782 GSPS--LDTHVRFTVNVMDENDNAPRFDQDVYYETVVENNDVGVQVARVRARDPDVGDNG 609

Query: 415 AWNAAYRISGGDPTGRFAILTDPNSNDGLVTVVKPIDFETNRMFVLTVAAENQVPLAK 472
             +  Y IS     G   +  D N   G +   +  D E N      V A ++  L K
Sbjct: 608 KVD--YSISSN--RGDVGVTMDRN---GYIIATRSFDHEQNHQLSFEVFATDRAILRK 456

 Score = 42.0 bits (97), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 37/122 (30%), Positives = 53/122 (43%), Gaps = 4/122 (3%)
 Frame = -2

Query: 265 PEFLHQVWNGSVPEGSKPGTYVMTVTAIDADDPNALNGMLRYRILSQAPST----PSPNM 320
           P F    +   V E +  GT V  V A D D  +  NG + Y +  + P      P    
Sbjct: 405 PSFKQDYYEVRVQENTAVGTSVGLVNAEDMDSND--NGRITYSLAWEHPQKMYFDPMDFH 232

Query: 321 FTINNETGDIITVAAGLDREKVQQYTLIIQATDMEGNPTYGLSNTATAVITVTDVNDNPP 380
             +       +T+   LD E   +Y L++ A D  G+P    + TAT  + V DVNDNPP
Sbjct: 231 IPLFVSPEGTLTLERQLDHEMTSEYNLLVLAVD-GGDP--ARTGTATITLLVEDVNDNPP 61

Query: 381 EF 382
           + 
Sbjct: 60  QI 55

 Score = 36.2 bits (82), Expect = 0.061,   Method: Compositional matrix adjust.
 Identities = 39/140 (27%), Positives = 62/140 (44%), Gaps = 8/140 (5%)
 Frame = -2

Query: 364 NTATAVITVTDVNDNPPEFTAMTFYGEVPENR-VDVIVANLTVTDKDQ------PHTPAW 416
           +TAT ++TV DVND  P F    +   V EN  V   V  +   D D        ++ AW
Sbjct: 453 STATVILTVMDVNDISPSFKQDYYEVRVQENTAVGTSVGLVNAEDMDSNDNGRITYSLAW 274

Query: 417 NAAYRISGGDPTGRFAILTDPNSNDGLVTVVKPIDFE-TNRMFVLTVAAENQVPLAKGIQ 475
               ++          +   P   +G +T+ + +D E T+   +L +A +   P   G  
Sbjct: 273 EHPQKMYFDPMDFHIPLFVSP---EGTLTLERQLDHEMTSEYNLLVLAVDGGDPARTG-- 109

Query: 476 HPPQSTATVSVTVIDVNENP 495
                TAT+++ V DVN+NP
Sbjct: 108 -----TATITLLVEDVNDNP 64
>37991
          Length = 843

 Score = 62.4 bits (150), Expect(2) = 1e-13,   Method: Compositional matrix adjust.
 Identities = 54/165 (32%), Positives = 80/165 (48%), Gaps = 1/165 (0%)
 Frame = +2

Query: 265 PEFLHQVWNGSVPEGSKPGTYVMTVTAIDADDPNALNGMLRYRILSQAPSTPSPNMFTIN 324
           P F    ++ S  E +  G  ++T T  DADD    N +L   I S      + N F++ 
Sbjct: 344 PNFNPATYSDSPLETAAAGGTLLTXTVTDADD--GANAVLVLSIASG----NTNNAFSL- 502

Query: 325 NETGDIITVAAGLDREKVQQYTLIIQATDMEGNPTYGLSNTATAVITVTDVNDNPPEFTA 384
             +G+ + +A  LD E  + Y LII+A D  G PT  L++ A   I+V   N++PP  T 
Sbjct: 503 --SGNDLVIANNLDYETTKNYDLIIEAAD-SGTPT-ALTSQARISISVQAANEDPPVLTD 670

Query: 385 MTFYGEVPENR-VDVIVANLTVTDKDQPHTPAWNAAYRISGGDPT 428
            TF   +PE++ V  ++   T TD DQ         + IS GD T
Sbjct: 671 TTFAATIPEDQAVGSLIYTATATDPDQDGNNDGTITFSISAGDTT 805

 Score = 33.1 bits (74), Expect(2) = 1e-13,   Method: Compositional matrix adjust.
 Identities = 22/47 (46%), Positives = 29/47 (61%), Gaps = 3/47 (6%)
 Frame = +3

Query: 185 SDRDKNL---SLRYSVTGPGADQPPTGIFIINPISGQLSVTKPLDRE 228
           +D D  L   ++ YS+TG G  Q   G FII+  +G +SV KPLDRE
Sbjct: 99  ADSDTGLYHGTVLYSITG-GNTQ---GDFIIDSSTGAISVAKPLDRE 227

 Score = 42.0 bits (97), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 54/191 (28%), Positives = 85/191 (44%), Gaps = 9/191 (4%)
 Frame = +2

Query: 345 YTLIIQATDMEGNPTYGLSNTATAVITVTDVNDNPPEFTAMTFYGEVPENRVDV--IVAN 402
           Y+L + A D         S+T    I +TDVNDN P F   T Y + P         +  
Sbjct: 239 YSLTVTAADDLAGSADEKSSTVVIAIAITDVNDNYPNFNPAT-YSDSPLETAAAGGTLLT 415

Query: 403 LTVTDKDQPHTPAWNAAYRISGGDPTGRFAILTDPNSNDGLVTVVKPIDFETNRMFVLTV 462
            TVTD D            I+ G+    F++     S + LV +   +D+ET + + L +
Sbjct: 416 XTVTDADDGANAVL--VLSIASGNTNNAFSL-----SGNDLV-IANNLDYETTKNYDLII 571

Query: 463 -AAENQVPLAKGIQHPPQSTATVSVTVIDVNENP------YFAPNPKIIRQEEGLHAGTM 515
            AA++  P A   Q      A +S++V   NE+P       FA     I +++ +  G++
Sbjct: 572 EAADSGTPTALTSQ------ARISISVQAANEDPPVLTDTTFA---ATIPEDQAV--GSL 718

Query: 516 LTTLTAQDPDR 526
           + T TA DPD+
Sbjct: 719 IYTATATDPDQ 751
>34098
          Length = 1349

 Score = 46.2 bits (108), Expect(3) = 3e-13,   Method: Compositional matrix adjust.
 Identities = 47/146 (32%), Positives = 70/146 (47%), Gaps = 2/146 (1%)
 Frame = +3

Query: 266 EFLHQVWNGSVPEGSKPGTYVMTVTAIDADDPNALNGMLRYRILSQAPSTPSPNMFTINN 325
            F   V+N S P  S+P T   + +     DP+   G ++ R+  +       + F I N
Sbjct: 672 RFSPSVYNVSYPS-SRPATPPWSRSG--GPDPDT-TGQVQLRLRGRGD-----DKFDIQN 824

Query: 326 ETGDIITVAAGLDREKVQQYTLIIQATDMEGNPTYGLSNTATAV-ITVTDVNDNPPEFTA 384
           + G I+ VA  LDRE   +YTLI+ A D       G+  T+ +V I ++D NDN P FT 
Sbjct: 825 D-GTIVAVALPLDRESEDRYTLIVTADD-------GVHTTSASVTIAISDSNDNRPRFTQ 980

Query: 385 MTFYGEVPENR-VDVIVANLTVTDKD 409
             +  +V E+      VA +T  D D
Sbjct: 981 DFYSFDVHEDTDRGATVARVTALDAD 1058

 Score = 35.8 bits (81), Expect(3) = 3e-13,   Method: Compositional matrix adjust.
 Identities = 28/95 (29%), Positives = 45/95 (47%), Gaps = 5/95 (5%)
 Frame = +1

Query: 410  QPHTPAWNAAYRIS----GGDPTGRFAILTDPNSNDGLVTVVKPIDFETNRMFVLTVAAE 465
            +P  P W    R++        T RF +    +S  G  T++  +D+E  +++ L V A 
Sbjct: 1042 RPWMPTWGENARVTYDLLSDWATDRFQL----DSVLGTFTLIGGLDYELRQLYTLRVVAR 1209

Query: 466  NQVPLAKGIQHPPQSTATVSVTVIDVNEN-PYFAP 499
            +      G   P  +T TV + V+DVN+N P F P
Sbjct: 1210 D------GGSPPMSTTTTVYMNVVDVNDNQPEFDP 1296

 Score = 31.2 bits (69), Expect(3) = 3e-13,   Method: Compositional matrix adjust.
 Identities = 20/56 (35%), Positives = 29/56 (51%), Gaps = 2/56 (3%)
 Frame = +2

Query: 192 SLRYSVTG-PGADQPPTGIFIINPISGQLSVTKPLDRELIA-RFHLRAHAVDINGN 245
           S+ Y +TG     Q   G+F ++  SG ++ T  LDRE +   F L   AV+  GN
Sbjct: 443 SIEYYLTGITSQGQQRGGLFRVDSSSGVVTTTTKLDREALGDEFTLSITAVEKGGN 610

 Score = 41.2 bits (95), Expect(2) = 2e-06,   Method: Compositional matrix adjust.
 Identities = 32/94 (34%), Positives = 46/94 (48%)
 Frame = +1

Query: 301  NGMLRYRILSQAPSTPSPNMFTINNETGDIITVAAGLDREKVQQYTLIIQATDMEGNPTY 360
            N  + Y +LS   +    + F +++  G   T+  GLD E  Q YTL + A D    P  
Sbjct: 1069 NARVTYDLLSDWAT----DRFQLDSVLG-TFTLIGGLDYELRQLYTLRVVARDGGSPP-- 1227

Query: 361  GLSNTATAVITVTDVNDNPPEFTAMTFYGEVPEN 394
             +S T T  + V DVNDN PEF   ++   + EN
Sbjct: 1228 -MSTTTTVYMNVVDVNDNQPEFDPASYTQLLYEN 1326

 Score = 29.3 bits (64), Expect(2) = 2e-06,   Method: Compositional matrix adjust.
 Identities = 23/77 (29%), Positives = 30/77 (38%)
 Frame = +3

Query: 219 LSVTKPLDRELIARFHLRAHAVDINGNQXXXXXXXXXXXXXXXXXRPEFLHQVWNGSVPE 278
           ++V  PLDRE   R+ L   A D                      RP F    ++  V E
Sbjct: 837 VAVALPLDRESEDRYTLIVTADD---GVHTTSASVTIAISDSNDNRPRFTQDFYSFDVHE 1007

Query: 279 GSKPGTYVMTVTAIDAD 295
            +  G  V  VTA+DAD
Sbjct: 1008DTDRGATVARVTALDAD 1058

 Score = 44.7 bits (104), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 29/77 (37%), Positives = 41/77 (53%), Gaps = 1/77 (1%)
 Frame = +1

Query: 532  IRYTKLSDPA-NWLKIDPVNGQITTIAVLDRESPNVKNNIYNATFLASDNGIPPMSGTGT 590
            + Y  LSD A +  ++D V G  T I  LD E       +Y    +A D G PPMS T T
Sbjct: 1078 VTYDLLSDWATDRFQLDSVLGTFTLIGGLDYE----LRQLYTLRVVARDGGSPPMSTTTT 1245

Query: 591  LQIYLLDINDNAPQVLP 607
            + + ++D+NDN P+  P
Sbjct: 1246 VYMNVVDVNDNQPEFDP 1296
>08409
          Length = 890

 Score = 72.8 bits (177), Expect = 6e-13,   Method: Compositional matrix adjust.
 Identities = 81/288 (28%), Positives = 130/288 (45%), Gaps = 6/288 (2%)
 Frame = +3

Query: 275 SVPEGSKPGTYVMTVTAIDADDPNALNGMLRYRILSQAPSTPSPNMFTINNETGDIITVA 334
           ++ E    G+++  VTA D D  N  N  L+Y+     P T     F IN  +G+I T+ 
Sbjct: 96  NILENQPRGSHIGEVTASDRDAGN--NQRLQYQF--SVPQT----QFAINTYSGEISTLG 251

Query: 335 AGLDREKVQQYTLIIQATDMEGNPTYGLSNTATAVITVTDVNDNPPEFTAMTFYGEVPEN 394
             LDRE+ + YTL +  TD +G P   LS++    I V D NDN P+F    +   V EN
Sbjct: 252 P-LDREQQELYTLWVYVTD-QGQPE--LSDSTVVKIEVLDENDNRPKFMEDVYRRSVEEN 419

Query: 395 R---VDVIVANLTVTDKDQPHTPAWNAAYRISGGDPTGRFAILTDPNSNDGLVTVVKPID 451
           R   + V+      TD  +  T  + + +R S  D    F+I    ++  G +   + +D
Sbjct: 420 RPKGLHVLTVVAQDTDAGENGTVTF-SFHRDSDADALTHFSI----HAAKGWIITEEVLD 584

Query: 452 FETNRMF-VLTVAAENQVPLAKGIQHPPQSTATVSVTVIDVN-ENPYFAPNPKIIRQEEG 509
           +ET   + +L +A +N  P          S+A V + V D N E P F          E 
Sbjct: 585 YETQTQYRLLVIAHDNGQPRLS-------SSAEVLIDVADANDEAPLFHAREVTFYVVEN 743

Query: 510 LHAGTMLTTLTAQDPDRYMQQNIRYTKL-SDPANWLKIDPVNGQITTI 556
           +  GT++  + A+D D      + Y  +  +  +   ++P  G I T+
Sbjct: 744 VAIGTVVGEVKARDRDSGENGRVTYYLVGGNVFSLFSVNPATGMIQTV 887

 Score = 26.9 bits (58), Expect(2) = 0.24,   Method: Composition-based stats.
 Identities = 10/28 (35%), Positives = 20/28 (71%)
 Frame = +1

Query: 585 MSGTGTLQIYLLDINDNAPQVLPQEAET 612
           +S T  ++I+++D NDNAP+    E+++
Sbjct: 13  LSATADIRIHIIDTNDNAPEFSRSESKS 96

 Score = 25.8 bits (55), Expect(2) = 0.24,   Method: Compositional matrix adjust.
 Identities = 19/85 (22%), Positives = 41/85 (48%), Gaps = 1/85 (1%)
 Frame = +3

Query: 623 ITALDYDIDPNAG-PFAFDLPLSPVTIKRNWTINRLNGDFAQLNLKIKFLEAGIYEVPII 681
           +TA D D   N    + F +P      +  + IN  +G+ + L   +   +  +Y + + 
Sbjct: 138 VTASDRDAGNNQRLQYQFSVP------QTQFAINTYSGEISTLG-PLDREQQELYTLWVY 296

Query: 682 ITDSGNPPKSNISILRVKVCQCDSN 706
           +TD G P  S+ ++++++V   + N
Sbjct: 297 VTDQGQPELSDSTVVKIEVLDENDN 371
>29507
          Length = 1143

 Score = 66.6 bits (161), Expect = 4e-11,   Method: Compositional matrix adjust.
 Identities = 91/323 (28%), Positives = 136/323 (42%), Gaps = 14/323 (4%)
 Frame = +2

Query: 185 SDRDK--NLSLRYSVTGPGADQPPTGIFIINPISGQLSVTKPLDRELIARFHLRAHAVDI 242
           +DRD   N  +RYS+        P+G F I+P +G + + +PLD E  + F L   A D 
Sbjct: 17  TDRDSGPNGRIRYSIDNK---TDPSGHFRIDPDTGVVRINRPLDYETQSTFTLTLEATD- 184

Query: 243 NGNQXXXXXXXXXXXXXXXXXRPEFLHQVWNGS------VPEGSKPGTYVMTVTAIDADD 296
           +G                   +P  +  V+  S      + E ++ GT V  ++  D D 
Sbjct: 185 HGPTRLVGNAALEVTLENINEQPANIRLVFLQSPGREQHIMENTREGTLVARISIDDPDI 364

Query: 297 PNALNGMLRYRILSQAPSTPSPNMFTINNETG--DIITVAAGLDREKVQQYTLIIQATDM 354
               +  +   +          ++F +    G   ++ V +  DRE    Y L +  TD 
Sbjct: 365 SADRHDDVDVNLFG------GDDIFGLQVSEGSLSLVVVNSPPDRENKSSYLLTVTVTD- 523

Query: 355 EGNPTYGLSNTATAVITVTDVNDNPPEFTAMTFYGEVPENR-VDVIVANLTVTDKDQPHT 413
            G P      + T  I + D NDN P F   ++ GEVPE   +   V  +T +D+D    
Sbjct: 524 SGTPPLHARQSFT--IYIDDENDNAPTFEG-SYEGEVPETADIGTFVVKVTASDRDAGDN 694

Query: 414 PAWNAAYRI-SGGDPTGR-FAILTDPNSNDGLVTVVKPIDFETNRMFVLTVAAENQ-VPL 470
                +Y I SG  P    FAI    +S  G++T   PID E N   VLTV A +  VP 
Sbjct: 695 ARL--SYSIESGSSPQAVWFAI----DSKTGVITTQTPIDCEVNARPVLTVVARDHGVPS 856

Query: 471 AKGIQHPPQSTATVSVTVIDVNE 493
             G       + +V VTV DVN+
Sbjct: 857 LSG-------STSVVVTVRDVND 904

 Score = 63.2 bits (152), Expect = 5e-10,   Method: Compositional matrix adjust.
 Identities = 83/314 (26%), Positives = 134/314 (42%), Gaps = 10/314 (3%)
 Frame = +2

Query: 301 NGMLRYRILSQAPSTPSPNMFTINNETGDIITVAAGLDREKVQQYTLIIQATDMEGNPTY 360
           NG +RY I ++   T     F I+ +TG ++ +   LD E    +TL ++ATD    PT 
Sbjct: 38  NGRIRYSIDNK---TDPSGHFRIDPDTG-VVRINRPLDYETQSTFTLTLEATDH--GPTR 199

Query: 361 GLSNTATAVITVTDVNDNPPEFTAMTFYG-----EVPEN-RVDVIVANLTVTDKDQPHTP 414
            + N A  V T+ ++N+ P     +          + EN R   +VA +++ D D     
Sbjct: 200 LVGNAALEV-TLENINEQPANIRLVFLQSPGREQHIMENTREGTLVARISIDDPDISADR 376

Query: 415 AWNAAYRISGGDPTGRFAILTDPNSNDGLVTVVKPIDFETNRMFVLTVAA-ENQVPLAKG 473
             +    + GGD    F +     S   LV V  P D E    ++LTV   ++  P    
Sbjct: 377 HDDVDVNLFGGDDI--FGLQVSEGSL-SLVVVNSPPDRENKSSYLLTVTVTDSGTP---- 535

Query: 474 IQHPPQSTATVSVTVIDVNENPYFAPNPKIIRQEEGLHAGTMLTTLTAQDPDRYMQQNIR 533
              P  +  + ++ + D N+N             E    GT +  +TA D D      + 
Sbjct: 536 ---PLHARQSFTIYIDDENDNAPTFEGSYEGEVPETADIGTFVVKVTASDRDAGDNARLS 706

Query: 534 YTKLSDP---ANWLKIDPVNGQITTIAVLDRESPNVKNNIYNATFLASDNGIPPMSGTGT 590
           Y+  S     A W  ID   G ITT   +D E     N     T +A D+G+P +SG+ +
Sbjct: 707 YSIESGSSPQAVWFAIDSKTGVITTQTPIDCE----VNARPVLTVVARDHGVPSLSGSTS 874

Query: 591 LQIYLLDINDNAPQ 604
           + + + D+ND  P+
Sbjct: 875 VVVTVRDVNDKQPE 916

 Score = 58.9 bits (141), Expect = 8e-09,   Method: Compositional matrix adjust.
 Identities = 63/224 (28%), Positives = 102/224 (45%), Gaps = 15/224 (6%)
 Frame = +2

Query: 426 DPTGRFAILTDPNSNDGLVTVVKPIDFETNRMFVLTVAAENQVPLAKGIQHPPQSTATVS 485
           DP+G F I  DP++  G+V + +P+D+ET   F LT+ A +  P            A + 
Sbjct: 74  DPSGHFRI--DPDT--GVVRINRPLDYETQSTFTLTLEATDHGPTRL------VGNAALE 223

Query: 486 VTVIDVNENP-----YFAPNPKIIRQE---EGLHAGTMLTTLTAQDPDRYMQQNIRY-TK 536
           VT+ ++NE P      F  +P   R++   E    GT++  ++  DPD    ++      
Sbjct: 224 VTLENINEQPANIRLVFLQSPG--REQHIMENTREGTLVARISIDDPDISADRHDDVDVN 397

Query: 537 LSDPANWLKIDPVNGQITTIAVL---DRESPNVKNNIYNATFLASDNGIPPMSGTGTLQI 593
           L    +   +    G ++ + V    DRE+     + Y  T   +D+G PP+    +  I
Sbjct: 398 LFGGDDIFGLQVSEGSLSLVVVNSPPDREN----KSSYLLTVTVTDSGTPPLHARQSFTI 565

Query: 594 YLLDINDNAPQVLPQ-EAETCETPEPNS--INITALDYDIDPNA 634
           Y+ D NDNAP      E E  ET +  +  + +TA D D   NA
Sbjct: 566 YIDDENDNAPTFEGSYEGEVPETADIGTFVVKVTASDRDAGDNA 697

 Score = 58.5 bits (140), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 45/123 (36%), Positives = 66/123 (53%)
 Frame = +2

Query: 272 WNGSVPEGSKPGTYVMTVTAIDADDPNALNGMLRYRILSQAPSTPSPNMFTINNETGDII 331
           + G VPE +  GT+V+ VTA D D  +  N  L Y I  ++ S+P    F I+++TG +I
Sbjct: 611 YEGEVPETADIGTFVVKVTASDRDAGD--NARLSYSI--ESGSSPQAVWFAIDSKTG-VI 775

Query: 332 TVAAGLDREKVQQYTLIIQATDMEGNPTYGLSNTATAVITVTDVNDNPPEFTAMTFYGEV 391
           T    +D E   +  L + A D  G P+  LS + + V+TV DVND  PEF    +   V
Sbjct: 776 TTQTPIDCEVNARPVLTVVARD-HGVPS--LSGSTSVVVTVRDVNDKQPEFDTSFYNARV 946

Query: 392 PEN 394
            E+
Sbjct: 947 AED 955
>19661
          Length = 684

 Score = 59.7 bits (143), Expect = 5e-09,   Method: Compositional matrix adjust.
 Identities = 65/227 (28%), Positives = 97/227 (42%), Gaps = 2/227 (0%)
 Frame = +1

Query: 221 VTKPLDRELIARFHLRAHAVDINGNQXXXXXXXXXXXXXXXXXRPEFLHQVWNGSVPEGS 280
           V   LDRE   R+ L   A D++ +                   P F    +  +V E +
Sbjct: 46  VAGQLDRESQERYQLVLRASDVS-SASYADMHLTVILQDVNDNSPVFESLRYTHTVSEVA 222

Query: 281 KPGTYVMTVTAIDADDPNALNGMLRYRILSQAPSTPSPNMFTINNETGDIITVAAGLDRE 340
           + GT ++ V A D    +A N ++ Y +   +  +     F +++ETG I+ +   LD E
Sbjct: 223 RVGTSILQVAARDX--DBAANSLIHYSLAPLSADSADTQPFFVHSETGTIV-LHRPLDHE 393

Query: 341 KVQQYTLIIQATDMEGNPTYGLSNTATAVITVTDVNDNPPEFTAMTFYGEVPE--NRVDV 398
               YT +  ATD  G P    S TA   I V D+NDN P FT ++F   + +  +R  +
Sbjct: 394 AQADYTFLAVATD-SGMP--ARSATALVHIIVLDLNDNXPHFTQLSFNCYITDQAHRGQL 564

Query: 399 IVANLTVTDKDQPHTPAWNAAYRISGGDPTGRFAILTDPNSNDGLVT 445
           +     VT  D   +   N  Y I GG+    F I    NS  GL+T
Sbjct: 565 VTK---VTGMDADDSDKGNLVYSIIGGNEKQAFTI----NSASGLIT 684

 Score = 38.1 bits (87), Expect = 0.014,   Method: Compositional matrix adjust.
 Identities = 57/225 (25%), Positives = 92/225 (40%), Gaps = 8/225 (3%)
 Frame = +1

Query: 443 LVTVVKPIDFETNRMFVLTVAAENQVPLAKGIQHPPQSTATVSVTVIDVNEN-PYFAPNP 501
           LV V   +D E+   + L + A +    +    H       ++V + DVN+N P F    
Sbjct: 37  LVLVAGQLDRESQERYQLVLRASDVSSASYADMH-------LTVILQDVNDNSPVFESLR 195

Query: 502 KIIRQEEGLHAGTMLTTLTAQDPDRYMQQNIRYTKLSDPANWLKIDP--VNGQITTIAVL 559
                 E    GT +  + A+D D      I Y+     A+     P  V+ +  TI VL
Sbjct: 196 YTHTVSEVARVGTSILQVAARDXDBAANSLIHYSLAPLSADSADTQPFFVHSETGTI-VL 372

Query: 560 DRESPNVKNNIYNATFLASDNGIPPMSGTGTLQIYLLDINDNAPQVLPQEAETCETPEPN 619
            R   +     Y    +A+D+G+P  S T  + I +LD+NDN P    Q +  C   +  
Sbjct: 373 HRPLDHEAQADYTFLAVATDSGMPARSATALVHIIVLDLNDNXPH-FTQLSFNCYITDQA 549

Query: 620 S-----INITALDYDIDPNAGPFAFDLPLSPVTIKRNWTINRLNG 659
                   +T +D D D + G   + +       K+ +TIN  +G
Sbjct: 550 HRGQLVTKVTGMDAD-DSDKGNLVYSIIGG--NEKQAFTINSASG 675
>14391
          Length = 642

 Score = 55.5 bits (132), Expect = 9e-08,   Method: Compositional matrix adjust.
 Identities = 47/174 (27%), Positives = 74/174 (42%)
 Frame = +1

Query: 210 FIINPISGQLSVTKPLDRELIARFHLRAHAVDINGNQXXXXXXXXXXXXXXXXXRPEFLH 269
           F I+ + G +  T+ LDRE   R+    +A D + +                  +P FL+
Sbjct: 61  FTIDTMLGDIYTTRFLDRETTPRYVFNIYAYDKSASPLTAVTTVVVNVADKNDMKPVFLN 240

Query: 270 QVWNGSVPEGSKPGTYVMTVTAIDADDPNALNGMLRYRILSQAPSTPSPNMFTINNETGD 329
             ++  V E + PG+ +  V A+D D    LN  + Y ++   PS   P  F I   T  
Sbjct: 241 SSYHFHVDERTPPGSMIGDVKAVDKD--IGLNARVEYYMV---PSKSRPR-FPITVNTSG 402

Query: 330 IITVAAGLDREKVQQYTLIIQATDMEGNPTYGLSNTATAVITVTDVNDNPPEFT 383
            I V   +D E    +T ++ A D+   P    ++T    I V D ND+ P  T
Sbjct: 403 AILVTDEVDYEMSNLFTFMVAAVDLGTPPR---NSTCHVTIEVMDKNDHSPVIT 555

 Score = 43.9 bits (102), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 52/178 (29%), Positives = 79/178 (44%), Gaps = 4/178 (2%)
 Frame = +1

Query: 321 FTINNETGDIITVAAGLDREKVQQYTLIIQATDMEGNPTYGLSNTATAVITVTDVNDNPP 380
           FTI+   GDI T    LDRE   +Y   I A D   +P   L+   T V+ V D ND  P
Sbjct: 61  FTIDTMLGDIYTTRF-LDRETTPRYVFNIYAYDKSASP---LTAVTTVVVNVADKNDMKP 228

Query: 381 EFTAMTFYGEVPENRV-DVIVANLTVTDKDQPHTPAWNA--AYRISGGDPTGRFAILTDP 437
            F   +++  V E      ++ ++   DKD       NA   Y +       RF I  + 
Sbjct: 229 VFLNSSYHFHVDERTPPGSMIGDVKAVDKDI----GLNARVEYYMVPSKSRPRFPITVN- 393

Query: 438 NSNDGLVTVVKPIDFETNRMFVLTVAAENQVPLAKGIQHPPQ-STATVSVTVIDVNEN 494
               G + V   +D+E + +F   VAA +       +  PP+ ST  V++ V+D N++
Sbjct: 394 --TSGAILVTDEVDYEMSNLFTFMVAAVD-------LGTPPRNSTCHVTIEVMDKNDH 540

 Score = 29.6 bits (65), Expect = 6.1,   Method: Compositional matrix adjust.
 Identities = 24/111 (21%), Positives = 47/111 (42%)
 Frame = +1

Query: 495 PYFAPNPKIIRQEEGLHAGTMLTTLTAQDPDRYMQQNIRYTKLSDPANWLKIDPVNGQIT 554
           P F  +      +E    G+M+  + A D D  +   + Y  +  P+      P+    +
Sbjct: 226 PVFLNSSYHFHVDERTPPGSMIGDVKAVDKDIGLNARVEYYMV--PSKSRPRFPITVNTS 399

Query: 555 TIAVLDRESPNVKNNIYNATFLASDNGIPPMSGTGTLQIYLLDINDNAPQV 605
              ++  E     +N++     A D G PP + T  + I ++D ND++P +
Sbjct: 400 GAILVTDEVDYEMSNLFTFMVAAVDLGTPPRNSTCHVTIEVMDKNDHSPVI 552
>17709
          Length = 812

 Score = 54.7 bits (130), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 60/203 (29%), Positives = 96/203 (47%), Gaps = 6/203 (2%)
 Frame = -3

Query: 323 INNETGDIITVAAGLDREKVQQYTLIIQATDMEGNPTYGLSNTATAVITVTDVNDNPPEF 382
           ++  TG + T+   LDRE V  Y++ + A D  G+P   LS+TAT ++TV D NDN P+F
Sbjct: 681 VDRNTGRVTTLQT-LDREAVPSYSIKVIAKD-GGSP--ALSSTATILLTVKDRNDNMPQF 514

Query: 383 TAMTFYGEVPE-NRVDVIVANLTVTDKDQPHTPAWNAAYRISGGDPTGRFAILTDPNSND 441
              ++Y  V E +     V  ++ +DKD         +YR  G      F+I +  +SN 
Sbjct: 513 HPDSYYVTVFETDAAGAKVVQVSASDKDAG--SFGRVSYRFIGTT----FSIFS-IDSNT 355

Query: 442 GLVTVVKPIDFETNRMFVLTVAAENQVPLAKGIQHPPQSTATVSVTVIDV---NENPYFA 498
           G++T    +   +   + LTV A +           PQ +   SVTVI        P F 
Sbjct: 354 GVITTTNVLRRASRSSYQLTVGAND--------GRSPQLSVRASVTVIVARLDGTAPAFT 199

Query: 499 PNPKI--IRQEEGLHAGTMLTTL 519
              K+  I ++ G+ A ++  T+
Sbjct: 198 SQTKVFEITEDFGVQASSLGQTV 130

 Score = 42.4 bits (98), Expect = 8e-04,   Method: Compositional matrix adjust.
 Identities = 32/98 (32%), Positives = 48/98 (48%), Gaps = 5/98 (5%)
 Frame = -3

Query: 546 IDPVNGQITTIAVLDRES-PNVKNNIYNATFLASDNGIPPMSGTGTLQIYLLDINDNAPQ 604
           +D   G++TT+  LDRE+ P+     Y+   +A D G P +S T T+ + + D NDN PQ
Sbjct: 681 VDRNTGRVTTLQTLDREAVPS-----YSIKVIAKDGGSPALSSTATILLTVKDRNDNMPQ 517

Query: 605 VLPQE--AETCETPEPNS--INITALDYDIDPNAGPFA 638
             P        ET    +  + ++A D D    AG F 
Sbjct: 516 FHPDSYYVTVFETDAAGAKVVQVSASDKD----AGSFG 415
>18709
          Length = 501

 Score = 50.8 bits (120), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 27/81 (33%), Positives = 40/81 (49%)
 Frame = +2

Query: 521 AQDPDRYMQQNIRYTKLSDPANWLKIDPVNGQITTIAVLDRESPNVKNNIYNATFLASDN 580
           A DPD     NI Y+ L +P +   IDPV G +  +   DRE+     + Y     A D 
Sbjct: 23  AMDPDMGNNGNITYSLLENPESAFAIDPVTGTLRAMKKFDREN----RSHYRVMVQAKDR 190

Query: 581 GIPPMSGTGTLQIYLLDINDN 601
           G P M+   T+ + + D+ND+
Sbjct: 191 GTPSMTSIATIHVNISDVNDS 253

 Score = 50.4 bits (119), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 49/169 (28%), Positives = 78/169 (46%), Gaps = 1/169 (0%)
 Frame = +2

Query: 286 VMTVTAIDADDPNALNGMLRYRILSQAPSTPSPNMFTINNETGDIITVAAGLDREKVQQY 345
           +  V A+D D  N  NG + Y +L    S      F I+  TG  +      DRE    Y
Sbjct: 8   IFQVLAMDPDMGN--NGNITYSLLENPESA-----FAIDPVTG-TLRAMKKFDRENRSHY 163

Query: 346 TLIIQATDMEGNPTYGLSNTATAVITVTDVNDNPPEFTAMTFYGEVPENR-VDVIVANLT 404
            +++QA D  G P+  +++ AT  + ++DVND+P  F    F   V E R    IV  L 
Sbjct: 164 RVMVQAKD-RGTPS--MTSIATIHVNISDVNDSPTHFAQSHFNFYVEEERPRGTIVDILR 334

Query: 405 VTDKDQPHTPAWNAAYRISGGDPTGRFAILTDPNSNDGLVTVVKPIDFE 453
           V D D+  +     ++      P+ +F+I    + + G +T  +P+D E
Sbjct: 335 VVDLDEKTSNQLQYSFLSEFAAPS-QFSI----DVSSGRITTTRPLDRE 466

 Score = 43.9 bits (102), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 44/141 (31%), Positives = 68/141 (48%), Gaps = 4/141 (2%)
 Frame = +2

Query: 426 DPTGRFAILTDPNSNDGLVTVVKPIDFETNRMFVLTVAAENQ-VPLAKGIQHPPQSTATV 484
           +P   FAI  DP +  G +  +K  D E    + + V A+++  P    I       AT+
Sbjct: 77  NPESAFAI--DPVT--GTLRAMKKFDRENRSHYRVMVQAKDRGTPSMTSI-------ATI 223

Query: 485 SVTVIDVNENP-YFAPNPKIIRQEEGLHAGTMLTTLTAQDPDRYMQQNIRYTKLSDPA-- 541
            V + DVN++P +FA +      EE    GT++  L   D D      ++Y+ LS+ A  
Sbjct: 224 HVNISDVNDSPTHFAQSHFNFYVEEERPRGTIVDILRVVDLDEKTSNQLQYSFLSEFAAP 403

Query: 542 NWLKIDPVNGQITTIAVLDRE 562
           +   ID  +G+ITT   LDRE
Sbjct: 404 SQFSIDVSSGRITTTRPLDRE 466
>18019
          Length = 571

 Score = 50.1 bits (118), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 50/171 (29%), Positives = 77/171 (45%)
 Frame = -1

Query: 210 FIINPISGQLSVTKPLDRELIARFHLRAHAVDINGNQXXXXXXXXXXXXXXXXXRPEFLH 269
           F I+P SG +++ KPL    I ++     A D   N                   P F +
Sbjct: 484 FYISPDSGVVNLRKPLYTNNINQYVCIVQASDQRSNARLTNATVTINVIRSQP--PRFQN 311

Query: 270 QVWNGSVPEGSKPGTYVMTVTAIDADDPNALNGMLRYRILSQAPSTPSPNMFTINNETGD 329
             ++ +V E +  G  V  VTA DAD    L+G+L Y ++  A   P+P+ F +N  TG 
Sbjct: 310 TPYSFTVSERTSVGASVYRVTAFDAD----LDGVLVYEVVGVA---PAPSYFQLNTTTG- 155

Query: 330 IITVAAGLDREKVQQYTLIIQATDMEGNPTYGLSNTATAVITVTDVNDNPP 380
           +I+    L  +  Q Y L ++A D    PT  ++    ++  V   NDNPP
Sbjct: 154 VISPRVDLKVDTTQNYLLRVRAYD-SAFPT-QVTEADVSIFVVR--NDNPP 14
>01558
          Length = 2767

 Score = 48.9 bits (115), Expect = 8e-06,   Method: Compositional matrix adjust.
 Identities = 92/364 (25%), Positives = 142/364 (39%), Gaps = 17/364 (4%)
 Frame = +2

Query: 185  SDRDKNLSLRYSVTGPGADQPPTGI---FIINPISGQLSVTKPL--DRELIARFHLRAHA 239
            +D   N ++ Y++ G  ++  PT +   F INP SG L+V+  L  D  +   + L   A
Sbjct: 1409 ADSGDNGAITYNIDGDKSE--PTYVNQYFYINPTSGSLAVSSRLSDDTNMPVLYVLYVVA 1582

Query: 240  VDINGNQXXXXXXXXXXXXXXXXXRPEFLHQVWNGSVPEGSKPGTYVMTVTAIDADDPNA 299
            +D NG                    P F   ++N +V E       ++ VTA DAD    
Sbjct: 1583 ID-NGVVRRSSFIRVRVTVVRNRNSPVFSQSLYNVTVDETIGVTQSLIRVTASDAD---- 1747

Query: 300  LNGMLRYRILSQAPSTPSPNMFTINNETGDIITVAAGLDREKVQQYTLIIQATDMEGNPT 359
                + Y +LS   S P+   F +++ +G I+ +   L ++    YT+ I+A D    P 
Sbjct: 1748 -GDRITYSMLS---SIPASLYFDVDSTSG-IVRIRNSLLQDSTVTYTMDIEALDA---PV 1903

Query: 360  YGLS--NTATAVITVTDVNDNPPEFTAMTFYGEVPENR-VDVIVANLTVTDKDQPHTPAW 416
             G S  N    VI     N N P F    +   V E   V  ++  +   D D   TP+ 
Sbjct: 1904 QGASPRNALAKVIVNVRRNPNTPIFDQSVYNVTVSEYIPVRSVIQTVLARDADAASTPSG 2083

Query: 417  NAAYRI---SGGDPTGRFA------ILTDPNSNDGLVTVVKPIDFETNRMFVLTVAAENQ 467
               Y I   S  DP    A       +  P + D ++          +R  ++  AA++ 
Sbjct: 2084 RLVYSIVSVSYPDPQFNVAPQQADFFIASPTTGDIILAQQLSQARVPDRFDIVIKAADSA 2263

Query: 468  VPLAKGIQHPPQSTATVSVTVIDVNENPYFAPNPKIIRQEEGLHAGTMLTTLTAQDPDRY 527
            +P       P  S   +SV +I     P F         E+    G  L T+TA D D  
Sbjct: 2264 IP-------PKSSQTLLSVNIIRNIHRPEFTEIRYGAAIEDTWAVGRTLFTVTAVDDDDK 2422

Query: 528  MQQN 531
             Q N
Sbjct: 2423 EQYN 2434

 Score = 32.3 bits (72), Expect = 0.98,   Method: Compositional matrix adjust.
 Identities = 34/118 (28%), Positives = 45/118 (38%), Gaps = 5/118 (4%)
 Frame = +2

Query: 264  RPEFLHQVWNGSVPEGSKPGTYVMTVTAIDADDP-----NALNGMLRYRILSQAPSTPSP 318
            RPEF    +  ++ +    G  + TVTA+D DD      N  N    Y I    P   + 
Sbjct: 2321 RPEFTEIRYGAAIEDTWAVGRTLFTVTAVDDDDKEQYNQNTNNAFFDYMIDENYPLAETY 2500

Query: 319  NMFTINNETGDIITVAAGLDREKVQQYTLIIQATDMEGNPTYGLSNTATAVITVTDVN 376
               TI+     ++ V   L  +    Y   I A D    P   LSN A   I VT  N
Sbjct: 2501 FGVTIDG----VVYVRNNLLLDNSASYFFYIIAIDRSWQP---LSNRAPVTINVTKTN 2653
>13573
          Length = 765

 Score = 48.5 bits (114), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 41/115 (35%), Positives = 57/115 (49%), Gaps = 7/115 (6%)
 Frame = -1

Query: 302 GMLRYRILSQAPSTPSPNMFTINNETGDIITVAAGLDREKVQ------QYTLIIQATDME 355
           G +RY +   A  +   N+FTI+++   +I+    LD E V       QY L++   +  
Sbjct: 447 GKIRYELYDDA--SQRSNVFTIDDQ--GLISNLQVLDYESVDRSLQPLQYRLVLWVHEDL 280

Query: 356 GNPTYGLSNTATAVITVTDVNDNPPEFTAMTFYGEVPENR-VDVIVANLTVTDKD 409
              T  LSN AT +ITV D+NDN PEF    +   V EN  V   VA +T  D D
Sbjct: 279 DXKT--LSNNATLIITVQDMNDNKPEFETSQYLTTVRENLPVHASVAEVTALDLD 121
>08534
          Length = 885

 Score = 47.8 bits (112), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 65/220 (29%), Positives = 99/220 (45%), Gaps = 11/220 (5%)
 Frame = -3

Query: 317 SPNMFTINNETGDIITVAAGLDREKVQQYTLIIQATDMEGNPTYGLSNTATAVITV---- 372
           +PN F IN  TG +I+V   L  +    Y L IQA+D  G P+  L +     I V    
Sbjct: 784 APNYFNINPNTG-VISVTQSLFGDSASSYRLRIQASD-GGKPS--LVDYEVVTINVDRNS 617

Query: 373 ---TDVNDNPPEFTAMTFYGEVPENRVDVIVANLTVTDKDQPHTPAWN-AAYRI--SGGD 426
              + VN + P +T+ T   +V E  +D      +V+ +D      +N   Y +   G  
Sbjct: 616 FTPSWVNPSAPFYTSTT---QVLET-IDYSTILFSVSARDNDIIAPYNQVTYSLVNQGKA 449

Query: 427 PTGRFAILTDPNSNDGLVTVVKPIDFETNRMF-VLTVAAENQVPLAKGIQHPPQSTATVS 485
           PT       D N   G + +   +  +T++ + VL  AA+N +P    +Q     TATV 
Sbjct: 448 PT-----FFDVNPTSGEIRLRSSLLQDTDQSYSVLLTAADNGIPSEVALQ-----TATVV 299

Query: 486 VTVIDVNENPYFAPNPKIIRQEEGLHAGTMLTTLTAQDPD 525
           V V+     PYF  +P  I   E    G+ + +LTA+D D
Sbjct: 298 VNVLRNLNTPYFVGSPYAITIAETTSVGSSIFSLTARDDD 179
>14946
          Length = 1599

 Score = 47.8 bits (112), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 88/353 (24%), Positives = 141/353 (39%), Gaps = 9/353 (2%)
 Frame = -3

Query: 210  FIINPISGQLSVTKP--LDRELIARFHLRAHAVDING-NQXXXXXXXXXXXXXXXXXRPE 266
            F +   SGQLSV +P  LD++    + L   A D+   ++                  P 
Sbjct: 1435 FQVGSSSGQLSVLQPLYLDQDRTQTYQLTITARDLGFPSRAATNTATVTVAVNRNNNPPF 1256

Query: 267  FLHQVWNGSVPEGSKPGTYVMTVTAIDADDPNALNGMLRYRILSQAPSTPSPNMFTINNE 326
            F++  ++ ++   +  GT V+ VT  DAD     N +     L       +P  F++ N+
Sbjct: 1255 FINTPYDVTISTPAASGTSVIPVTVTDADSVAPFNTVS----LQVIGDDSAPIYFSLGND 1088

Query: 327  TGDIITVAAGLDREKVQQYTLIIQATDMEGNPTYGLSNTATAVITVT-DVNDNPPEFT-A 384
                ++  + L+ +    Y + + ATD  G P    S TATA + +T   N   P+FT  
Sbjct: 1087 RIIRVSNVSNLNTDTATFYRMRLLATDF-GYP----SRTATATVGITVRRNLFSPQFTNT 923

Query: 385  MTFYGEVPEN-RVDVIVANLTVTDKDQPHTPAWNAAYRIS---GGDPTGRFAILTDPNSN 440
             T    +PE   +   + +L  TD D   T A N  ++ S    GD    F I    N  
Sbjct: 922  NTIRVTIPETAAIGTFITDLNATDSD---TDAPNNEFQFSLVGVGDSVNFFFI----NPL 764

Query: 441  DGLVTVVKPIDFETNRMFVLTVAAENQVPLAKGIQHPPQSTATVSVTVIDVNENPYFAPN 500
            DG +T++  ++   N  + L      +V +  G      S   V VTV+   E   F   
Sbjct: 763  DGRITLLNSVENTVNSGYQL------RVRVTDGGNPQLFSETLVEVTVVRDTETLVFTLP 602

Query: 501  PKIIRQEEGLHAGTMLTTLTAQDPDRYMQQNIRYTKLSDPANWLKIDPVNGQI 553
               +   E L    ++T++ AQ  D       R T  SD  ++  I    G I
Sbjct: 601  RYTVDISENLAENRIVTSVVAQPQDSVTY---RLTGYSDGPDYFNISSSTGSI 452

 Score = 43.5 bits (101), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 65/275 (23%), Positives = 118/275 (42%), Gaps = 11/275 (4%)
 Frame = -3

Query: 439  SNDGLVTVVKPIDFETNRM--FVLTVAAENQVPLAKGIQHPPQS---TATVSVTVIDVNE 493
            S+ G ++V++P+  + +R   + LT+ A       + +  P ++   TATV+V V   N 
Sbjct: 1423 SSSGQLSVLQPLYLDQDRTQTYQLTITA-------RDLGFPSRAATNTATVTVAVNRNNN 1265

Query: 494  NPYFAPNPKIIRQEEGLHAGTMLTTLTAQDPDRYMQQN-IRYTKLSDPANWLKIDPVNGQ 552
             P+F   P  +       +GT +  +T  D D     N +    + D +  +     N +
Sbjct: 1264 PPFFINTPYDVTISTPAASGTSVIPVTVTDADSVAPFNTVSLQVIGDDSAPIYFSLGNDR 1085

Query: 553  ITTIAVLDRESPNVKNNIYNATFLASDNGIPPMSGTGTLQIYLLDINDNAPQVLPQEAET 612
            I  ++ +   + +     Y    LA+D G P  + T T+ I +   N  +PQ        
Sbjct: 1084 IIRVSNVSNLNTDTA-TFYRMRLLATDFGYPSRTATATVGITVRR-NLFSPQFTNTNTIR 911

Query: 613  CETPEPNSI-----NITALDYDIDPNAGPFAFDLPLSPVTIKRNWTINRLNGDFAQLNLK 667
               PE  +I     ++ A D D D     F F L     ++   + IN L+G    LN  
Sbjct: 910  VTIPETAAIGTFITDLNATDSDTDAPNNEFQFSLVGVGDSVNF-FFINPLDGRITLLNSV 734

Query: 668  IKFLEAGIYEVPIIITDSGNPPKSNISILRVKVCQ 702
               + +G Y++ + +TD GNP   + +++ V V +
Sbjct: 733  ENTVNSG-YQLRVRVTDGGNPQLFSETLVEVTVVR 632
>12240
          Length = 977

 Score = 44.7 bits (104), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 34/100 (34%), Positives = 45/100 (45%), Gaps = 2/100 (2%)
 Frame = +2

Query: 336 GLDREKVQQYTLIIQATDMEGNPTYGLSNTATAVITVTDVNDNPPEFTAMTFYGEV--PE 393
            LD E   Q+   +Q  D  G P    S  A  V+ +TD+ND PP FT  ++  +V  P 
Sbjct: 509 ALDHEAKSQFNFTVQVHD-RGVPRLSASAPAPVVVYITDINDTPPRFTQSSYTAKVVLPT 685

Query: 394 NRVDVIVANLTVTDKDQPHTPAWNAAYRISGGDPTGRFAI 433
              DV V  +   D D   T      Y I+GG+    FAI
Sbjct: 686 YH-DVRVVKVEAEDPDTISTKPLT--YSIAGGNEGSVFAI 796

 Score = 36.6 bits (83), Expect = 0.047,   Method: Compositional matrix adjust.
 Identities = 24/76 (31%), Positives = 39/76 (51%), Gaps = 2/76 (2%)
 Frame = +1

Query: 321 FTINNETGDIITVAAGLDREKVQQYTLIIQATDMEGNPTYGLSNTATA--VITVTDVNDN 378
           F +N  +G +++    +D E    + L I A ++       +S TA    ++ V D NDN
Sbjct: 139 FFLNXNSG-VVSTTRAIDYEHHHFFNLTILAANI-------VSATAVTHMLVHVGDENDN 294

Query: 379 PPEFTAMTFYGEVPEN 394
            P+FTA  F+G V E+
Sbjct: 295 RPQFTAQAFFGNVSES 342
>14137
          Length = 815

 Score = 42.7 bits (99), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 47/164 (28%), Positives = 77/164 (46%), Gaps = 3/164 (1%)
 Frame = -1

Query: 273 NGSVPEGSKPGTYVMTVTAIDADDPNALNGMLRYRILSQAPSTPSPNMFTINNETGDIIT 332
           N +V E    G+ ++ ++A DAD  N  NG + Y +      +   N F+++  +G++ T
Sbjct: 629 NITVDEEQPIGSLILQLSATDADTGN--NGQVFYGL--DPDLSGQFNSFSVDAVSGNL-T 465

Query: 333 VAAGLDREKVQQYTLIIQATDMEGNPTYGLSNTATAVITVTDVNDNPPEF-TAMTFYGEV 391
               LDRE+   + + ++A D +G PT  LS      + + DVNDN P F    T    V
Sbjct: 464 NKQILDREQTDMFQISLKAED-QGTPTR-LSTVIPFRVFLRDVNDNDPRFPPPATLTLSV 291

Query: 392 PENRVDVIVANLTVTDKDQPHTPAWN--AAYRISGGDPTGRFAI 433
            E   +V+V ++ +   D  H P       Y   GGD    F++
Sbjct: 290 GEELQNVVVGSVDIA-VDDDHDPENKIICYYIYGGGDKVNSFSL 162
>33808
          Length = 445

 Score = 41.6 bits (96), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 37/120 (30%), Positives = 57/120 (47%), Gaps = 2/120 (1%)
 Frame = +3

Query: 265 PEFLHQVWNGSVPEGSKPGTYVMTVTAIDADDPNALNGMLRYRILSQAPSTPSPNMFTIN 324
           P F+   +  ++   +     V+  TA+DAD    L G++RY ++    + P+P  F IN
Sbjct: 27  PNFVSLPYRTTIQRSTAINATVVRATAVDAD----LQGVIRYSVVG---NYPAPTFFDIN 185

Query: 325 NETGDI-ITVAAGLDREKVQQYTLIIQATDMEGNPTYGLSNTATAVITV-TDVNDNPPEF 382
             +GDI +  +  LD     QY + + A D     T   +N ATA  T+  D N N P F
Sbjct: 186 PASGDIFVKQSLALDSLLSTQYIVAVIAYD-----TVYPNNIATATATIFVDRNPNGPIF 350
>18725
          Length = 934

 Score = 39.3 bits (90), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 32/90 (35%), Positives = 46/90 (51%), Gaps = 7/90 (7%)
 Frame = -1

Query: 340 EKVQQYTLIIQATDMEGNPTYGLSNTATAVITVT--DVNDNPPEFTAMTFYGEVPE---- 393
           E    YT+  +AT++  N +   + T TAV +VT  D NDNPP F+  T+Y  + E    
Sbjct: 436 EVTYGYTITAKATELYSNGS-KTNATTTAVFSVTIDDANDNPPTFSDDTYYVTIKEMEQI 260

Query: 394 -NRVDVIVANLTVTDKDQPHTPAWNAAYRI 422
              V +    + VTD D+P     NA YR+
Sbjct: 259 NGTVQIPNLRMGVTDLDEPS----NAQYRM 182
>29492
          Length = 440

 Score = 38.9 bits (89), Expect = 0.009,   Method: Compositional matrix adjust.
 Identities = 23/46 (50%), Positives = 29/46 (63%), Gaps = 1/46 (2%)
 Frame = +1

Query: 481 TATVSVTVIDVN-ENPYFAPNPKIIRQEEGLHAGTMLTTLTAQDPD 525
           TATV+V ++D+N +NPYF P    I   E    GT +TTLTA D D
Sbjct: 253 TATVTVNILDINNKNPYFDPPTTSINISESAPIGTPVTTLTAIDKD 390
>19334
          Length = 923

 Score = 38.1 bits (87), Expect = 0.014,   Method: Compositional matrix adjust.
 Identities = 22/53 (41%), Positives = 29/53 (54%), Gaps = 2/53 (3%)
 Frame = +3

Query: 337 LDREKVQQYTLIIQATDMEGNPTYGLSNTATAVITVT--DVNDNPPEFTAMTF 387
            DRE+  QYT+++Q  D+   P     +TA  V+ VT  DVNDN P F    F
Sbjct: 84  FDREQQDQYTVVVQVVDLNPEP-----HTAHVVVMVTIEDVNDNTPMFVKQPF 227

 Score = 31.6 bits (70), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 36/152 (23%), Positives = 61/152 (40%), Gaps = 22/152 (14%)
 Frame = +3

Query: 559 LDRESPNVKNNIYNATFLASDNGIPPMSGTGTLQIYLLDINDNAPQVLPQEAET---CET 615
            DRE    + + Y       D    P +    + + + D+NDN P  + Q  +T    +T
Sbjct: 84  FDRE----QQDQYTVVVQVVDLNPEPHTAHVVVMVTIEDVNDNTPMFVKQPFKTIVSTDT 251

Query: 616 PEPNSI-NITALDYDIDPNAGPFAFDLPLSPV-TIKRNWTINRLNGDFA----------- 662
               ++  +TA D D+  N G   + LP+     +K  + IN+  GD             
Sbjct: 252 EHGETVKKVTAADGDLGDN-GEIRYFLPMHLTDNVKDAFAINQYTGDIVVRRLTEDDRDT 428

Query: 663 QLNLKIKFLEAG------IYEVPIIITDSGNP 688
              L ++ ++ G        EVPI + DS +P
Sbjct: 429 TFLLTVEAVDQGSPPLSATVEVPIHVVDSSSP 524
>38442
          Length = 393

 Score = 32.7 bits (73), Expect = 0.63,   Method: Compositional matrix adjust.
 Identities = 19/45 (42%), Positives = 25/45 (55%)
 Frame = -3

Query: 559 LDRESPNVKNNIYNATFLASDNGIPPMSGTGTLQIYLLDINDNAP 603
           LDRE    K + Y    +ASD G P  SG+  + I + D+NDN P
Sbjct: 259 LDRE----KMSSYFLQVVASDGGFPQRSGSVNITINVQDVNDNVP 137
>27585
          Length = 389

 Score = 32.3 bits (72), Expect = 0.90,   Method: Compositional matrix adjust.
 Identities = 18/51 (35%), Positives = 27/51 (52%)
 Frame = -3

Query: 553 ITTIAVLDRESPNVKNNIYNATFLASDNGIPPMSGTGTLQIYLLDINDNAP 603
           I+T+  LD E      ++Y     A+D  +   S T T+ IY+LD+ DN P
Sbjct: 384 ISTVQGLDYE----IQSLYLLVVEAADGAVDRRSSTATVTIYVLDVEDNVP 244
>18690
          Length = 498

 Score = 32.0 bits (71), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 32/105 (30%), Positives = 49/105 (46%), Gaps = 11/105 (10%)
 Frame = +3

Query: 289 VTAIDADDPNA-----LNGMLRYRILSQAPSTPSPNMFTINNETGDIITVAAGLDREKVQ 343
           +T+I   DP+      L   +RY +L   P+      F++NNETG +      L R+  Q
Sbjct: 33  ITSISCRDPDLTSQQQLTSRIRYTLLGFQPADL---YFSLNNETGQV-----SLTRDLTQ 188

Query: 344 ------QYTLIIQATDMEGNPTYGLSNTATAVITVTDVNDNPPEF 382
                  Y L+++  D   NPT  L +  T V++V + N N P F
Sbjct: 189 DPYNSGTYVLVVECYD-RLNPT--LRDQTTVVVSV-NRNPNCPAF 311
>29111
          Length = 320

 Score = 30.8 bits (68), Expect = 2.6,   Method: Compositional matrix adjust.
 Identities = 27/58 (46%), Positives = 32/58 (55%), Gaps = 1/58 (1%)
 Frame = +2

Query: 551 GQITTIAVLDRESPNVKNNIYNATFLASDNGIPPMSGTGTLQIY-LLDINDNAPQVLP 607
           G+ITT A LDRE+  V +  Y  +FL   N     SGT  L I  LLD+NDN P   P
Sbjct: 170 GRITTKANLDRET--VPSGFY--SFLLQTNN----SGTIVLVIVRLLDVNDNDPSFTP 319

 Score = 28.9 bits (63), Expect = 8.6,   Method: Compositional matrix adjust.
 Identities = 34/113 (30%), Positives = 47/113 (41%), Gaps = 5/113 (4%)
 Frame = +2

Query: 276 VPEGSKPGTYVMTVTAIDADDPNALNGMLRYRILSQAPSTPSPNMFTINNETGDIITVAA 335
           V E    G+YV TVT       N  N      ++          +F++   TG I T  A
Sbjct: 35  VEENVANGSYVGTVT-------NPANTAGFNDLIPGNAQQDGTQVFSVVLSTGRI-TTKA 190

Query: 336 GLDREKVQQ--YTLIIQATDMEGNPTYGLSNTATAVITVT---DVNDNPPEFT 383
            LDRE V    Y+ ++Q            +N+ T V+ +    DVNDN P FT
Sbjct: 191 NLDRETVPSGFYSFLLQT-----------NNSGTIVLVIVRLLDVNDNDPSFT 316
>00918
          Length = 1559

 Score = 30.8 bits (68), Expect = 2.8,   Method: Compositional matrix adjust.
 Identities = 11/23 (47%), Positives = 15/23 (65%)
 Frame = -1

Query: 37  PEDVYSAVLPKDVHEGQPLLNVK 59
           P  ++ + LPKD+  GQPL N K
Sbjct: 665 PSKIWFSALPKDIKAGQPLFNKK 597
>24587
          Length = 2023

 Score = 30.0 bits (66), Expect = 4.1,   Method: Compositional matrix adjust.
 Identities = 42/169 (24%), Positives = 72/169 (42%), Gaps = 15/169 (8%)
 Frame = -3

Query: 549  VNGQITTIAVLD---RESPNVKNNIYNATFLASDNGIPPMSGTGTLQIYLLDINDNAPQV 605
            +NG I  I VLD   +E   +   ++++  + S + I        + I ++DINDN P V
Sbjct: 1553 LNGSIENIRVLDYEEQEEYKLCVLVHSSPTVDSTSRIVDNDTVAHITISIVDINDNGP-V 1377

Query: 606  LPQEAETC--ETPEPNSINITALDYDID-PNAGPFAFDLPL---------SPVTIKRNWT 653
             P    T   ET     + I  L  D D P      +D+            P ++K  +T
Sbjct: 1376 FPANTYTAVLETIPSEDVVIQVLANDPDGPLNSRTVYDIRTIMYYPPNDRRPFSMKGAFT 1197

Query: 654  INRLNGDFAQLNLKIKFLEAGIYEVPIIITDSGNPPKSNISILRVKVCQ 702
            IN LNG    +    +    G +E+ ++  D  N   ++ +++ V V +
Sbjct: 1196 INPLNGVITAILPSYEDFAQGYFEIQVLAFDVQNQLFNDSAVVMVVVIE 1050
>15121
          Length = 2573

 Score = 30.0 bits (66), Expect = 4.4,   Method: Composition-based stats.
 Identities = 23/82 (28%), Positives = 39/82 (47%)
 Frame = +2

Query: 276 VPEGSKPGTYVMTVTAIDADDPNALNGMLRYRILSQAPSTPSPNMFTINNETGDIITVAA 335
           V EG+ PG  V  + A+D D+ +  NG + +     A S      FT++  +   + VA 
Sbjct: 65  VSEGASPGHVVAKMAAVDEDEGD--NGEVEFFF---AGSVTGEVPFTVH--SNGTVVVAG 223

Query: 336 GLDREKVQQYTLIIQATDMEGN 357
            LDRE+ + +   + A    G+
Sbjct: 224 VLDREESESHVFTVLARGQGGH 289
>12703
          Length = 1529

 Score = 30.0 bits (66), Expect = 4.9,   Method: Compositional matrix adjust.
 Identities = 34/130 (26%), Positives = 57/130 (43%), Gaps = 1/130 (0%)
 Frame = -3

Query: 477 PPQSTATVSVTVIDVNENPYFAPNPKIIRQEEGLHAGTMLTTLTAQDPDRYMQQ-NIRYT 535
           PP  T      V  V EN   APN  +++ +  L     +  L   DPD  +   +  Y 
Sbjct: 480 PPTITTNSGSFVGYVYEN---APNGTLVKTDSSL---VTVLRLLISDPDVALSDPDANYE 319

Query: 536 KLSDPANWLKIDPVNGQITTIAVLDRESPNVKNNIYNATFLASDNGIPPMSGTGTLQIYL 595
            + +PA   +++  +  +    +LD E+    + I++      D      S T TL + +
Sbjct: 318 IVLNPATTFEVNVDSRSVILRGLLDYETR--PSYIFDVIVRELDTE-ERFSSTVTLTVSV 148

Query: 596 LDINDNAPQV 605
           LD+NDNAP +
Sbjct: 147 LDVNDNAPFI 118

 Score = 28.9 bits (63), Expect = 9.6,   Method: Compositional matrix adjust.
 Identities = 24/75 (32%), Positives = 36/75 (48%), Gaps = 2/75 (2%)
 Frame = -3

Query: 321 FTINNETGDIITVAAGLDREKVQQYT--LIIQATDMEGNPTYGLSNTATAVITVTDVNDN 378
           F +N ++  +I +   LD E    Y   +I++  D E       S+T T  ++V DVNDN
Sbjct: 294 FEVNVDSRSVI-LRGLLDYETRPSYIFDVIVRELDTEER----FSSTVTLTVSVLDVNDN 130

Query: 379 PPEFTAMTFYGEVPE 393
            P   +  F   VPE
Sbjct: 129 APFIPSAIFNQFVPE 85
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|90403603|ref|NP_035341.2| protein tyrosine
phosphatase, receptor type, D isoform B [Mus musculus]
         (1508 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

17679                                                                 127   3e-29
17840                                                                 124   3e-28
30741                                                                 119   9e-27
29613                                                                  99   2e-20
15655                                                                  96   1e-19
19962                                                                  84   4e-16
19544                                                                  77   4e-14
19713                                                                  67   5e-11
14634                                                                  65   3e-10
17631                                                                  61   3e-09
17229                                                                  60   5e-09
35419                                                                  40   1e-08
29990                                                                  54   2e-07
06028                                                                  53   8e-07
19200                                                                  53   1e-06
08294                                                                  50   5e-06
30215                                                                  49   2e-05
11855                                                                  47   8e-05
07196                                                                  45   2e-04
20110                                                                  44   3e-04
36498                                                                  31   0.002
25766                                                                  40   0.008
07945                                                                  38   0.024
17530                                                                  38   0.035
25697                                                                  37   0.069
18345                                                                  37   0.079
20244                                                                  32   0.19 
14057                                                                  35   0.23 
38127                                                                  34   0.36 
25455                                                                  34   0.44 
13135                                                                  34   0.47 
12764                                                                  34   0.54 
32888                                                                  28   0.82 
37675                                                                  32   1.3  
25554                                                                  32   1.9  
30103                                                                  31   4.4  
08005                                                                  30   5.1  
34811                                                                  30   5.3  
27666                                                                  30   9.6  
>17679
          Length = 509

 Score =  127 bits (319), Expect = 3e-29,   Method: Compositional matrix adjust.
 Identities = 63/119 (52%), Positives = 84/119 (70%), Gaps = 1/119 (0%)
 Frame = +3

Query: 416 LTQTSEQAPSSAPRDVQARMLSSTTILVQWKEPEEPNGQIQGYRVYYTMDPTQHVNNWMK 475
           + Q   +AP +APR+V+AR  SSTTI+V W EPE PNG IQGYRV+YT  P + V  W +
Sbjct: 102 IVQVLVEAPGTAPRNVRARAASSTTIVVSWSEPEIPNGIIQGYRVFYTRKPEEPVFFWEQ 281

Query: 476 HNVA-DSQITTIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQPLNFKAEP 533
             V  D+++TTI  L P +TY++ +LA++SIG GP+S  IQV+T  GVP QPLN  A+P
Sbjct: 282 QEVKNDNRLTTISGLDPNQTYTISILAYSSIGPGPMSHPIQVLTTQGVPYQPLNLHADP 458

 Score = 73.6 bits (179), Expect = 5e-13,   Method: Compositional matrix adjust.
 Identities = 53/148 (35%), Positives = 80/148 (54%), Gaps = 11/148 (7%)
 Frame = +3

Query: 288 DMPIGRNVLELNDVRQSANYTCVAMSTLGVIEAIAQITVKALPKPPGTPVVTESTATSIT 347
           ++PIGRNVL+L DV++S N+TC A S LG IE I Q+ V+A    P       +++T+I 
Sbjct: 3   EIPIGRNVLQLKDVKESKNFTCEASSDLGNIERIVQVLVEAPGTAPRNVRARAASSTTIV 182

Query: 348 LTWDSGNPEPVSYYIIQ----HKPKNSEEPY-----KEI--DGIATTRYSVAGLSPYSDY 396
           ++W    PE +   IIQ       +  EEP      +E+  D   TT   ++GL P   Y
Sbjct: 183 VSWSE--PE-IPNGIIQGYRVFYTRKPEEPVFFWEQQEVKNDNRLTT---ISGLDPNQTY 344

Query: 397 EFRVVAVNNIGRGPASEPVLTQTSEQAP 424
              ++A ++IG GP S P+   T++  P
Sbjct: 345 TISILAYSSIGPGPMSHPIQVLTTQGVP 428
>17840
          Length = 437

 Score =  124 bits (311), Expect = 3e-28,   Method: Compositional matrix adjust.
 Identities = 59/116 (50%), Positives = 79/116 (68%), Gaps = 1/116 (0%)
 Frame = +1

Query: 1120 VPEHPTPFLAFLRRVKTCNPPDAGPMVVHCSAGVGRTGCFIVIDAMLERIKHEKTVDIYG 1179
            VP++  P L F+++   CNPPD GP+VVHCSAGVGRTG +I+ID+M+ +I  + TV+I G
Sbjct: 1    VPDYTLPVLEFVQKSAACNPPDGGPIVVHCSAGVGRTGTYILIDSMIRQIGDKHTVNIPG 180

Query: 1180 HVTLMRAQRNYMVQTEDQYIFIHDALLEAVTCGN-TEVPARNLYAYIQKLTQIETG 1234
                +R QRN +VQTEDQY+FIHD L+E +  G  TEV   N+  Y+  LT    G
Sbjct: 181  FTLHIRRQRNLLVQTEDQYMFIHDVLVEYLMGGGQTEVTNDNITNYVASLTSSTNG 348

 Score = 64.3 bits (155), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 31/67 (46%), Positives = 43/67 (64%)
 Frame = +1

Query: 1434 GPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDQYQFCY 1493
            GPI VHCSAGVGRTG +I +  ++ ++  +  V+I      +R QR  +VQTEDQY F +
Sbjct: 70   GPIVVHCSAGVGRTGTYILIDSMIRQIGDKHTVNIPGFTLHIRRQRNLLVQTEDQYMFIH 249

Query: 1494 RAALEYL 1500
               +EYL
Sbjct: 250  DVLVEYL 270
>30741
          Length = 506

 Score =  119 bits (298), Expect = 9e-27,   Method: Composition-based stats.
 Identities = 54/109 (49%), Positives = 72/109 (66%), Gaps = 1/109 (0%)
 Frame = -3

Query: 1102 SEKREVRQFQFTAWPDHGVPEHPTPFLAFLRRVKTCNP-PDAGPMVVHCSAGVGRTGCFI 1160
            S+ R ++ F F  WPDHG PE  +  L F+  V+   P   AGP +VHCSAGVGRTG FI
Sbjct: 432  SQSRMIKHFHFMRWPDHGCPERTSMLLNFVSSVRAHMPHTGAGPTLVHCSAGVGRTGTFI 253

Query: 1161 VIDAMLERIKHEKTVDIYGHVTLMRAQRNYMVQTEDQYIFIHDALLEAV 1209
             +D +L +I+ +  VDI+  V  MR  R YMVQTE+QY++IHD L +A+
Sbjct: 252  ALDRLLLQIRQQTEVDIFNLVLTMRDNRMYMVQTENQYVYIHDCLSDAL 106

 Score = 94.7 bits (234), Expect = 3e-19,   Method: Composition-based stats.
 Identities = 50/120 (41%), Positives = 68/120 (56%), Gaps = 1/120 (0%)
 Frame = -3

Query: 1375 MPQYILREFKVTDARDG-QSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQD 1433
            +P Y +R   V D + G QSR ++ F F  WP+ G P+     ++F+  V       G  
Sbjct: 474  LPDYNIR---VIDIKLGSQSRMIKHFHFMRWPDHGCPERTSMLLNFVSSVRAHMPHTGA- 307

Query: 1434 GPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDQYQFCY 1493
            GP  VHCSAGVGRTG FI L  +L ++R +  VDIF  V  +R  R  MVQTE+QY + +
Sbjct: 306  GPTLVHCSAGVGRTGTFIALDRLLLQIRQQTEVDIFNLVLTMRDNRMYMVQTENQYVYIH 127
>29613
          Length = 425

 Score = 98.6 bits (244), Expect = 2e-20,   Method: Compositional matrix adjust.
 Identities = 51/117 (43%), Positives = 69/117 (58%), Gaps = 4/117 (3%)
 Frame = -2

Query: 1089 YCVRTFALYK-NGSSEKREVRQFQFTAWPDHGVPEHPTPFLAFLRRVKTCNPPDAGPMVV 1147
            Y +RTF +YK +   E R+V+Q+    W D+     P   L F+  V+  +    GPMVV
Sbjct: 352  YTIRTFTIYKEDQEDESRQVKQYFIPGWEDYSANLSPDDVLDFISSVRLESRGCQGPMVV 173

Query: 1148 HCSAGVGRTGCFIVIDAMLERIKHEKT---VDIYGHVTLMRAQRNYMVQTEDQYIFI 1201
            HCSAGVGRTG FI +D +++ ++       VDIY  V  MR  R YMVQ+E QYI+I
Sbjct: 172  HCSAGVGRTGTFIALDFLMQFVRDHDLNDEVDIYNLVLNMRHNRPYMVQSEKQYIYI 2

 Score = 78.6 bits (192), Expect = 2e-14,   Method: Compositional matrix adjust.
 Identities = 45/117 (38%), Positives = 66/117 (56%), Gaps = 4/117 (3%)
 Frame = -2

Query: 1377 QYILREFKV-TDARDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGP 1435
            +Y +R F +  + ++ +SR V+Q+    W +     S +  +DFI  V    E  G  GP
Sbjct: 355  KYTIRTFTIYKEDQEDESRQVKQYFIPGWEDYSANLSPDDVLDFISSVRL--ESRGCQGP 182

Query: 1436 ISVHCSAGVGRTGVFITLSIVLERMRYEGV---VDIFQTVKMLRTQRPAMVQTEDQY 1489
            + VHCSAGVGRTG FI L  +++ +R   +   VDI+  V  +R  RP MVQ+E QY
Sbjct: 181  MVVHCSAGVGRTGTFIALDFLMQFVRDHDLNDEVDIYNLVLNMRHNRPYMVQSEKQY 11
>15655
          Length = 467

 Score = 95.9 bits (237), Expect = 1e-19,   Method: Compositional matrix adjust.
 Identities = 60/155 (38%), Positives = 80/155 (51%), Gaps = 16/155 (10%)
 Frame = +1

Query: 1055 ERSRVKCDQYWPSRGTETHGLVQVTLLDTVELATY--CVRTFALYKNG-SSEKREVRQFQ 1111
            ER R+KC QYWP          +  L+D   + TY   V T  + +N  + E REV   Q
Sbjct: 7    ERQRMKCGQYWPFEEQSDEQFEEF-LVDNKSVQTYKNYVETKLILRNTETDEWREVTHLQ 183

Query: 1112 FTAWPDHGVPEHPTPFLAFLRRVKTCNP-------------PDAGPMVVHCSAGVGRTGC 1158
            F +WPD+G+P   T FL FL  V+                 P   P+VVHCSAG+GRTG 
Sbjct: 184  FISWPDYGIPP-ATGFLDFLFHVREVQASATTKMGASWAGHPLGPPIVVHCSAGIGRTGT 360

Query: 1159 FIVIDAMLERIKHEKTVDIYGHVTLMRAQRNYMVQ 1193
            FI ID  L R++   TVD+   V  +R+QR + +Q
Sbjct: 361  FITIDISLRRLEDTGTVDVPVTVRRIRSQRAFSIQ 465

 Score = 95.9 bits (237), Expect = 1e-19,   Method: Compositional matrix adjust.
 Identities = 57/154 (37%), Positives = 80/154 (51%), Gaps = 13/154 (8%)
 Frame = +1

Query: 1344 EMGREKCHQYWPAERSARYQY--FVVDPMAEYNMPQYILREFKVTDARDGQSRTVRQFQF 1401
            E  R KC QYWP E  +  Q+  F+VD  +      Y+  +  + +    + R V   QF
Sbjct: 7    ERQRMKCGQYWPFEEQSDEQFEEFLVDNKSVQTYKNYVETKLILRNTETDEWREVTHLQF 186

Query: 1402 TDWPEQGVPKSGEGFIDFIGQVHK------TKEQFGQDG-----PISVHCSAGVGRTGVF 1450
              WP+ G+P +  GF+DF+  V +      TK      G     PI VHCSAG+GRTG F
Sbjct: 187  ISWPDYGIPPA-TGFLDFLFHVREVQASATTKMGASWAGHPLGPPIVVHCSAGIGRTGTF 363

Query: 1451 ITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQ 1484
            IT+ I L R+   G VD+  TV+ +R+QR   +Q
Sbjct: 364  ITIDISLRRLEDTGTVDVPVTVRRIRSQRAFSIQ 465
>19962
          Length = 410

 Score = 84.0 bits (206), Expect = 4e-16,   Method: Compositional matrix adjust.
 Identities = 48/132 (36%), Positives = 67/132 (50%), Gaps = 5/132 (3%)
 Frame = +1

Query: 1365 FVVDPMAEYNMPQYILREFKVTDARD-----GQSRTVRQFQFTDWPEQGVPKSGEGFIDF 1419
            + V     ++   ++ R   V+ A D     G SR V    FT WP+ GVP      + F
Sbjct: 22   YTVTSTKVFHRAHFVHRLLTVSQATDQNTGGGVSREVHLLHFTAWPDHGVP-CPVTLVRF 198

Query: 1420 IGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQR 1479
               V +   Q    GP+ VHCSAG+GRTG +I L ++  +    G V +F TV+ +R QR
Sbjct: 199  WSYVTRQPAQL--SGPLLVHCSAGIGRTGTYIALDMLTHQAETTGKVSVFPTVRRIRGQR 372

Query: 1480 PAMVQTEDQYQF 1491
              MVQT  QY+F
Sbjct: 373  VNMVQTISQYRF 408

 Score = 83.2 bits (204), Expect = 7e-16,   Method: Compositional matrix adjust.
 Identities = 43/103 (41%), Positives = 56/103 (54%)
 Frame = +1

Query: 1098 KNGSSEKREVRQFQFTAWPDHGVPEHPTPFLAFLRRVKTCNPPDAGPMVVHCSAGVGRTG 1157
              G    REV    FTAWPDHGVP  P   + F   V       +GP++VHCSAG+GRTG
Sbjct: 103  NTGGGVSREVHLLHFTAWPDHGVPC-PVTLVRFWSYVTRQPAQLSGPLLVHCSAGIGRTG 279

Query: 1158 CFIVIDAMLERIKHEKTVDIYGHVTLMRAQRNYMVQTEDQYIF 1200
             +I +D +  + +    V ++  V  +R QR  MVQT  QY F
Sbjct: 280  TYIALDMLTHQAETTGKVSVFPTVRRIRGQRVNMVQTISQYRF 408
>19544
          Length = 1421

 Score = 77.4 bits (189), Expect = 4e-14,   Method: Compositional matrix adjust.
 Identities = 68/226 (30%), Positives = 103/226 (45%), Gaps = 10/226 (4%)
 Frame = +2

Query: 396 YEFRVVAVNNIGRGPASEPVLTQTSEQAPSSAPRDVQARMLSSTTILVQWKE--PEEPNG 453
           YE +V+AVN  GRGP S P      E AP+  P +VQA   S+++I V W    PE  NG
Sbjct: 20  YEVQVLAVNGKGRGPPSTPATIYVGEAAPTEGPSNVQAVNKSASSIQVTWVAPPPETQNG 199

Query: 454 QIQGYRVYYTMDPTQHVNNWMKHNVADSQITTIGNLVPQKTYSVKVLAFTSIGDGPLSSD 513
            + GY+V Y    +      +    A++ I  + +L     Y + V  +   G+GP S+ 
Sbjct: 200 GLSGYKVLY-YKQSSSAEEELTRITAETHI-LLESLETFTVYFIAVQPYNLAGEGPRSAL 373

Query: 514 IQVITQTGVPGQPLNFKAEPESETSILLSWTPPRSDT--IASYELVYRDGDQGE-----E 566
           +   T  GVP  P + +    +   +++ + PP +    I  YE+ Y   D+        
Sbjct: 374 VSAQTSEGVPSAPQSIRFTNITMRQLMVHFDPPTTPNGHILLYEMQYFPKDESRYGFLAP 553

Query: 567 QRITIEPGTSYRLQGLKPNSLYYFRLSARSPQGLGAST-AEISART 611
           +RI     T   +  L+    Y F +SA +  G G S  AEI  RT
Sbjct: 554 KRILRANETRVVVTELEKRVWYKFIISANTSIGKGESLEAEIKNRT 691

 Score = 56.2 bits (134), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 85/306 (27%), Positives = 133/306 (43%), Gaps = 24/306 (7%)
 Frame = +2

Query: 342 TATSITLTWDSGNPEPVS-----YYIIQHKPKNSEEPYKEIDGI-ATTRYSVAGLSPYSD 395
           +A+SI +TW +  PE  +     Y ++ +K  +S E  +E+  I A T   +  L  ++ 
Sbjct: 143 SASSIQVTWVAPPPETQNGGLSGYKVLYYKQSSSAE--EELTRITAETHILLESLETFTV 316

Query: 396 YEFRVVAVNNIGRGPASEPVLTQTSEQAPSSAPRDVQARMLSSTTILVQWKEPEEPNGQI 455
           Y   V   N  G GP S  V  QTSE  P SAP+ ++   ++   ++V +  P  PNG I
Sbjct: 317 YFIAVQPYNLAGEGPRSALVSAQTSEGVP-SAPQSIRFTNITMRQLMVHFDPPTTPNGHI 493

Query: 456 QGYRV-YYTMDPTQHVNNWMKHNV-ADSQITTIGNLVPQKTYSVKVLAFTSIGDG-PLSS 512
             Y + Y+  D +++     K  + A+     +  L  +  Y   + A TSIG G  L +
Sbjct: 494 LLYEMQYFPKDESRYGFLAPKRILRANETRVVVTELEKRVWYKFIISANTSIGKGESLEA 673

Query: 513 DIQVITQTGVPGQPLNFKAEPESETSI----LLSWTPPRSDTIASYELVYRDGDQ----- 563
           +I+  T T V G P    A+  S   I    L  W   R+     + L++R   +     
Sbjct: 674 EIKNRTTTWVSGCPRT--AQC*SAVQIFPXDLERW---RAGVHQHFWLLHRSQAKRGSRL 838

Query: 564 -GEEQRITIEPGTSYRLQGLKPNSLYYFRLSARSPQGLGASTAEISARTMQSMF-----A 617
                RIT E         L PN+ Y FR+ A +  G+   +   S R +   F     A
Sbjct: 839 PNNPARITSESKAEIGWSSLNPNTGYQFRVMAINDDGISDESLP-SERVVTPSFAIVQKA 1015

Query: 618 KNFHVK 623
           K FH +
Sbjct: 1016KPFHTE 1033

 Score = 49.7 bits (117), Expect = 8e-06,   Method: Compositional matrix adjust.
 Identities = 38/133 (28%), Positives = 66/133 (49%), Gaps = 6/133 (4%)
 Frame = +2

Query: 489 LVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQ-PLNFKAEPESETSILLSWTPPR 547
           LV  +TY V+VLA    G GP S+   +      P + P N +A  +S +SI ++W  P 
Sbjct: 2   LVISQTYEVQVLAVNGKGRGPPSTPATIYVGEAAPTEGPSNVQAVNKSASSIQVTWVAPP 181

Query: 548 SDT----IASYE-LVYRDGDQGEEQRITIEPGTSYRLQGLKPNSLYYFRLSARSPQGLGA 602
            +T    ++ Y+ L Y+     EE+   I   T   L+ L+  ++Y+  +   +  G G 
Sbjct: 182 PETQNGGLSGYKVLYYKQSSSAEEELTRITAETHILLESLETFTVYFIAVQPYNLAGEGP 361

Query: 603 STAEISARTMQSM 615
            +A +SA+T + +
Sbjct: 362 RSALVSAQTSEGV 400
>19713
          Length = 417

 Score = 67.4 bits (163), Expect = 5e-11,   Method: Compositional matrix adjust.
 Identities = 43/124 (34%), Positives = 66/124 (53%), Gaps = 2/124 (1%)
 Frame = +3

Query: 1237 VTGMELEFKRLASSKAHTSRFISANLP-CNKFKNRLVNIMPYESTRVCLQPIRGVEGSDY 1295
            V+ ++  +K L  S+ H  +  S  +  C   KNR  +IMPY+ TRV L   +     DY
Sbjct: 3    VSRLDTAWKSLIDSQDHDLKKQSIAIARCYPMKNRDPDIMPYDETRVVLSTTKD----DY 170

Query: 1296 INASFLDGYRQQ-KAYIATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYW 1354
            INAS+++        ++ATQ PL  T  DFW M++E  S ++V +T   E  + K   Y+
Sbjct: 171  INASWINDLAPSCPKFVATQAPLNVTMMDFWDMVYELGSEVIVQITSEYETSK-KFPVYY 347

Query: 1355 PAER 1358
            P E+
Sbjct: 348  PTEK 359

 Score = 52.8 bits (125), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 36/105 (34%), Positives = 57/105 (54%), Gaps = 3/105 (2%)
 Frame = +3

Query: 979  KNRYANVIAYDHSRVLLSAIEGIPGSDYVNANYIDGYRKQN-AYIATQGSLPETFGDFWR 1037
            KNR  +++ YD +RV+LS  +     DY+NA++I+        ++ATQ  L  T  DFW 
Sbjct: 99   KNRDPDIMPYDETRVVLSTTKD----DYINASWINDLAPSCPKFVATQAPLNVTMMDFWD 266

Query: 1038 MIWEQRSATVVMMTKLEERSRVKCDQYWPSRGTET--HGLVQVTL 1080
            M++E  S  +V +T   E S+ K   Y+P+   +    G + VTL
Sbjct: 267  MVYELGSEVIVQITSEYETSK-KFPVYYPTEKGQAMEQGPMIVTL 398
>14634
          Length = 462

 Score = 64.7 bits (156), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 46/118 (38%), Positives = 58/118 (49%), Gaps = 9/118 (7%)
 Frame = +2

Query: 1232 ETGEN-------VTGMELEFKRLASSKAHTSR--FISANLPCNKFKNRLVNIMPYESTRV 1282
            E GEN       +   E +FKRL   +   S+    SA    N  KNR  +I+P E  RV
Sbjct: 56   EEGENSVLPAAIIQSSEDQFKRLEELRPILSKEDTTSALEDKNAGKNRSSDILPVEQFRV 235

Query: 1283 CLQPIRGVEGSDYINASFLDGYRQQKAYIATQGPLAETTEDFWRMLWEHNSTIVVMLT 1340
            CL      +G DYINA FL    +Q+ Y  TQ PL  T  DFWRM+ +   + VV  T
Sbjct: 236  CLSTANREDG-DYINAVFLPSLNRQQGYAMTQLPLHNTVVDFWRMVRDWRVSTVVRFT 406

 Score = 52.8 bits (125), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 29/76 (38%), Positives = 41/76 (53%)
 Frame = +2

Query: 976  NKPKNRYANVIAYDHSRVLLSAIEGIPGSDYVNANYIDGYRKQNAYIATQGSLPETFGDF 1035
            N  KNR ++++  +  RV LS      G DY+NA ++    +Q  Y  TQ  L  T  DF
Sbjct: 182  NAGKNRSSDILPVEQFRVCLSTANREDG-DYINAVFLPSLNRQQGYAMTQLPLHNTVVDF 358

Query: 1036 WRMIWEQRSATVVMMT 1051
            WRM+ + R +TVV  T
Sbjct: 359  WRMVRDWRVSTVVRFT 406
>17631
          Length = 442

 Score = 61.2 bits (147), Expect = 3e-09,   Method: Composition-based stats.
 Identities = 29/95 (30%), Positives = 51/95 (53%), Gaps = 3/95 (3%)
 Frame = +2

Query: 1404 WPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSI---VLERM 1460
            W  +G   + E  +  +  V +        GPI+VHCS+G GRTGV+I + I   ++   
Sbjct: 146  WLTEGDTVAPEDLLKVVSLVRQAARHC--QGPITVHCSSGTGRTGVYIAVDILHGLVSEN 319

Query: 1461 RYEGVVDIFQTVKMLRTQRPAMVQTEDQYQFCYRA 1495
              +  +D+F     L T RP ++Q++DQY++ + +
Sbjct: 320  SLDSEIDVFSLCHTLMTCRPNIIQSQDQYEYVHES 424

 Score = 58.5 bits (140), Expect = 2e-08,   Method: Composition-based stats.
 Identities = 35/138 (25%), Positives = 62/138 (44%), Gaps = 3/138 (2%)
 Frame = +2

Query: 1071 ETHGLVQVTLLDTVELATYCVRTFALYKNGSSEKREVRQFQFTAWPDHGVPEHPTPFLAF 1130
            + HG V V L    +L    VR+ ++      E   V       W   G    P   L  
Sbjct: 17   QRHGDVTVVLKSRRDLGHCTVRSLSVAMM-LHEPLHVTHVHMHGWLTEGDTVAPEDLLKV 193

Query: 1131 LRRVKTCNPPDAGPMVVHCSAGVGRTGCFIVID---AMLERIKHEKTVDIYGHVTLMRAQ 1187
            +  V+       GP+ VHCS+G GRTG +I +D    ++     +  +D++     +   
Sbjct: 194  VSLVRQAARHCQGPITVHCSSGTGRTGVYIAVDILHGLVSENSLDSEIDVFSLCHTLMTC 373

Query: 1188 RNYMVQTEDQYIFIHDAL 1205
            R  ++Q++DQY ++H+++
Sbjct: 374  RPNIIQSQDQYEYVHESV 427
>17229
          Length = 487

 Score = 60.5 bits (145), Expect = 5e-09,   Method: Compositional matrix adjust.
 Identities = 46/145 (31%), Positives = 74/145 (51%), Gaps = 10/145 (6%)
 Frame = +1

Query: 385 YSVAGLSPYSDYEFRVVAVNNIGRGPASEPVLTQTSEQAPSSAPRDVQARMLSSTTILVQ 444
           Y +  L+P + Y  +V A    G GP +  + T+T    P   PR ++A  ++ST I V+
Sbjct: 58  YRLHDLTPDTIYYIQVSAKTVHGEGPRTPTIQTKTLPFLPGE-PRKLRAETINSTGIFVE 234

Query: 445 WKEPEEPNGQIQGYRVYYTM------DP----TQHVNNWMKHNVADSQITTIGNLVPQKT 494
           W EP++  G+I+GY VYY        +P    T+ V++ +   V ++ I  IG L     
Sbjct: 235 WDEPKDSRGKIRGYYVYYVKVNGSRDEPPSGLTEQVHDTVSGRVKEAVI--IG-LDADSR 405

Query: 495 YSVKVLAFTSIGDGPLSSDIQVITQ 519
           Y V+V  +T  GDG  S  + + T+
Sbjct: 406 YRVQVAGYTRKGDGRRSKSLVIDTK 480

 Score = 43.9 bits (102), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 25/78 (32%), Positives = 37/78 (47%)
 Frame = +1

Query: 470 VNNWMKHNVADSQITTIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQPLNF 529
           VNN+  H+           L P   Y ++V A T  G+GP +  IQ  T   +PG+P   
Sbjct: 49  VNNYRLHD-----------LTPDTIYYIQVSAKTVHGEGPRTPTIQTKTLPFLPGEPRKL 195

Query: 530 KAEPESETSILLSWTPPR 547
           +AE  + T I + W  P+
Sbjct: 196 RAETINSTGIFVEWDEPK 249

 Score = 42.0 bits (97), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 18/69 (26%), Positives = 37/69 (53%), Gaps = 2/69 (2%)
 Frame = +1

Query: 573 PGTSYRLQGLKPNSLYYFRLSARSPQGLGASTAEISARTMQSMFA--KNFHVKAVMKTSV 630
           P  +YRL  L P+++YY ++SA++  G G  T  I  +T+  +    +    + +  T +
Sbjct: 46  PVNNYRLHDLTPDTIYYIQVSAKTVHGEGPRTPTIQTKTLPFLPGEPRKLRAETINSTGI 225

Query: 631 LLSWEIPEN 639
            + W+ P++
Sbjct: 226 FVEWDEPKD 252
>35419
          Length = 623

 Score = 40.0 bits (92), Expect(2) = 1e-08,   Method: Compositional matrix adjust.
 Identities = 24/69 (34%), Positives = 37/69 (53%), Gaps = 3/69 (4%)
 Frame = -1

Query: 357 PVSYYIIQHKPKNSEEPYK---EIDGIATTRYSVAGLSPYSDYEFRVVAVNNIGRGPASE 413
           PV YY+IQ+    + + +    ++D I T+  +   LSP+ +Y FRV+A N IG    S 
Sbjct: 203 PVQYYVIQYNTSFNPDTWTFAVQVDSIFTS--ANVSLSPWVNYTFRVIAYNKIGESDPSL 30

Query: 414 PVLTQTSEQ 422
           P  T+   Q
Sbjct: 29  PHPTRLPHQ 3

 Score = 38.9 bits (89), Expect(2) = 1e-08,   Method: Compositional matrix adjust.
 Identities = 34/111 (30%), Positives = 49/111 (44%), Gaps = 9/111 (8%)
 Frame = -2

Query: 249 PTNHEIMPGGSVNITCVAVGSP----MPYVKWMLGAEDL-TPEDDMP--IGRNVLELND- 300
           P + E+  G     TC     P    M  +KWM   +++ T E  M   I  N L ++  
Sbjct: 556 PMDLEVNAGTDAKFTCSGTTDPEEVHMLKIKWMKDNKEISTVEQRMTTNIQDNSLTISGT 377

Query: 301 -VRQSANYTCVAMSTLGVIEAIAQITVKALPKPPGTPVVTESTATSITLTW 350
            VR S  YTC++ + L   EA A +TVK  P    + V  E    + T+ W
Sbjct: 376 IVRDSGTYTCISTNGLDSAEASAMLTVKDRPD-VASEVKIEKCDDNATILW 227

 Score = 37.7 bits (86), Expect = 0.036,   Method: Compositional matrix adjust.
 Identities = 29/97 (29%), Positives = 42/97 (43%), Gaps = 9/97 (9%)
 Frame = -2

Query: 35  RTPVDQTGVSGGVASFICQATGDPRP----KIVWNKKGKKVSN--QRFEVIEFDDG---S 85
           + P+D    +G  A F C  T DP      KI W K  K++S   QR      D+    S
Sbjct: 562 QAPMDLEVNAGTDAKFTCSGTTDPEEVHMLKIKWMKDNKEISTVEQRMTTNIQDNSLTIS 383

Query: 86  GSVLRIQPLRTPRDEAIYECVASNNVGEISVSTRLTV 122
           G+++R        D   Y C+++N +     S  LTV
Sbjct: 382 GTIVR--------DSGTYTCISTNGLDSAEASAMLTV 296
>29990
          Length = 434

 Score = 48.9 bits (115), Expect(2) = 2e-07,   Method: Compositional matrix adjust.
 Identities = 36/119 (30%), Positives = 52/119 (43%), Gaps = 4/119 (3%)
 Frame = +3

Query: 56  GDPRPKIVWNKKGKKV---SNQRFEVIEFDDGSGSVLRIQPLRTPRDEAIYECVASNNVG 112
           G P P+IVW     +V    + RF ++   DG+  +   Q      D  +YEC+A N  G
Sbjct: 6   GKPVPEIVWMHNNNRVEISGDSRFSLLH--DGTLMIEDAQD----DDRGVYECIARNVAG 167

Query: 113 EI-SVSTRLTVLREDQIPRGFPTIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDF 170
           E  S    L    E    R  P     PQ  V    +T  ++C ASG+P P  +W ++ 
Sbjct: 168 ETHSNQVELRYFGE----RVAPXFTQRPQDIVTVEGQTVQLVCQASGHPRPTFSWTRNL 332

 Score = 25.8 bits (55), Expect(2) = 2e-07,   Method: Compositional matrix adjust.
 Identities = 10/20 (50%), Positives = 13/20 (65%)
 Frame = +2

Query: 197 GALQIEQSEESDQGKYECVA 216
           G L I   +ESD+G Y+C A
Sbjct: 374 GTLTIRNVQESDRGDYQCYA 433

 Score = 53.5 bits (127), Expect = 6e-07,   Method: Compositional matrix adjust.
 Identities = 38/126 (30%), Positives = 54/126 (42%)
 Frame = +3

Query: 158 GNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGGTPIRGALQIEQSEESDQGKYECVAT 217
           G P PEI W          +NN R+ ++  +S       G L IE +++ D+G YEC+A 
Sbjct: 6   GKPVPEIVWM---------HNNNRV-EISGDSRFSLLHDGTLMIEDAQDDDRGVYECIAR 155

Query: 218 NSAGTRYSAPANLYXXXXXXXXXXXXXFSIPPTNHEIMPGGSVNITCVAVGSPMPYVKWM 277
           N AG  +S    L              F+  P +   + G +V + C A G P P   W 
Sbjct: 156 NVAGETHSNQVEL----RYFGERVAPXFTQRPQDIVTVEGQTVQLVCQASGHPRPTFSWT 323

Query: 278 LGAEDL 283
              E L
Sbjct: 324 RNLEQL 341

 Score = 38.5 bits (88), Expect = 0.018,   Method: Compositional matrix adjust.
 Identities = 15/43 (34%), Positives = 23/43 (53%)
 Frame = +3

Query: 31  PRFTRTPVDQTGVSGGVASFICQATGDPRPKIVWNKKGKKVSN 73
           P FT+ P D   V G     +CQA+G PRP   W +  +++ +
Sbjct: 219 PXFTQRPQDIVTVEGQTVQLVCQASGHPRPTFSWTRNLEQLGS 347
>06028
          Length = 1358

 Score = 53.1 bits (126), Expect = 8e-07,   Method: Compositional matrix adjust.
 Identities = 69/293 (23%), Positives = 116/293 (39%), Gaps = 23/293 (7%)
 Frame = +1

Query: 62  IVWNKKGKKVSN-QRFEVIEFDDGSGSVLRIQPLRTPRDEAIYECVASNNVGEISVSTRL 120
           I W K  + +SN ++++ ++  DG   ++   P+   +D  +Y CVASN   +  +S ++
Sbjct: 4   IQWMKGTEPISNDEKYQQVDQADGYSKLIIHNPVE--KDSGVYFCVASNEGAQNKISHQV 177

Query: 121 TVLREDQIP----RGFPTID---------MGPQLKVVERTRTATMLCAASGNPDPEITWF 167
                ++       GF   D         +G Q      T   +     S  P  E+ W 
Sbjct: 178 DFKGRERFTLEKTAGFFHRDPNKPHFLNPLGNQTVCHGGTVAISAEFMQSSTP-IEVKWL 354

Query: 168 KDFLPVDTSNNNGRIKQLRSESIGGTPIRG--ALQIEQSEESDQGKYECVATNSAGTRYS 225
           ++  PVD     G   Q  +E       RG   L I  + E  +G Y C+A+N+ G R  
Sbjct: 355 RNRRPVD-----GPSVQTFNE-------RGIYTLAIMNAGEEHEGTYTCLASNAFG-RIE 495

Query: 226 APANLYXXXXXXXXXXXXXF-SIPPTNHEIMPGGSVNITCVAVGSPMPYVKWMLGAEDLT 284
           +  N+              F S P T  +I  G   +++    G P P + +M G +D+T
Sbjct: 496 SHVNIDVAVGVEKEVRPPLFLSRPETEMKIAVGDPFSLSFRIAGDPKPRLVFMKGTKDIT 675

Query: 285 PEDDMP------IGRNVLELNDVRQSANYTCVAMSTLGVIEAIAQITVKALPK 331
             D +         R  ++ + +  S  Y  VA +  G       IT+K   K
Sbjct: 676 QSDRVSKEVSDDYTRFTVQKSQISDSGTYFVVARNDFGTDRIFVTITIKTPKK 834
>19200
          Length = 436

 Score = 52.8 bits (125), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 37/126 (29%), Positives = 58/126 (46%), Gaps = 6/126 (4%)
 Frame = -2

Query: 439 TTILVQWKEPEEPNGQIQGYRVYYTMDPTQHVNNWMKHNVADSQITTIGNLVPQKTYSVK 498
           T+I V W   ++PN  + GY+++Y M  T  +  W +       +  I NL P   Y+V+
Sbjct: 432 TSIEVSW---DDPNFPVAGYKIFYNMFATPVMYVWQQMETGPYTVADISNLEPHTVYAVR 262

Query: 499 VLAFTSIGDGPLSSDIQVITQTGVPGQP------LNFKAEPESETSILLSWTPPRSDTIA 552
           V A +   DG   +  + +T T V G P       NF+        + LSW+PP+   + 
Sbjct: 261 VQAKSV--DGRFGNLSETVT-TSVNGDPERENVVRNFRVTSRLTNLVRLSWSPPKKPDVN 91

Query: 553 SYELVY 558
            Y L Y
Sbjct: 90  VYMLKY 73

 Score = 33.5 bits (75), Expect = 0.62,   Method: Compositional matrix adjust.
 Identities = 28/110 (25%), Positives = 51/110 (46%), Gaps = 8/110 (7%)
 Frame = -2

Query: 537 TSILLSWTPPRSDTIASYELVYR---DGDQGEEQRITIEPGTSYRLQGLKPNSLYYFRLS 593
           TSI +SW  P +  +A Y++ Y           Q++   P T   +  L+P+++Y  R+ 
Sbjct: 432 TSIEVSWDDP-NFPVAGYKIFYNMFATPVMYVWQQMETGPYTVADISNLEPHTVYAVRVQ 256

Query: 594 ARSPQGLGASTAEISARTM-----QSMFAKNFHVKAVMKTSVLLSWEIPE 638
           A+S  G   + +E    ++     +    +NF V + +   V LSW  P+
Sbjct: 255 AKSVDGRFGNLSETVTTSVNGDPERENVVRNFRVTSRLTNLVRLSWSPPK 106
>08294
          Length = 1849

 Score = 50.4 bits (119), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 34/120 (28%), Positives = 54/120 (45%), Gaps = 1/120 (0%)
 Frame = +2

Query: 103 YECVASN-NVGEISVSTRLTVLREDQIPRGFPTIDMGPQLKVVERTRTATMLCAASGNPD 161
           Y CVA++   G I+ +  ++++        +P I +      V    +A + C A G+P 
Sbjct: 5   YTCVATHPRQGVINATIHISIVE-------WPAITVKSNNITVFEGHSAILHCVAKGSPS 163

Query: 162 PEITWFKDFLPVDTSNNNGRIKQLRSESIGGTPIRGALQIEQSEESDQGKYECVATNSAG 221
           P+I W++D  P+     N R   L           G ++I Q    D G Y CVA N+AG
Sbjct: 164 PDIAWYRDSQPILP---NARRYTLFKN--------GTMKIRQVFMEDNGMYACVANNTAG 310

 Score = 35.4 bits (80), Expect = 0.19,   Method: Compositional matrix adjust.
 Identities = 32/136 (23%), Positives = 51/136 (37%)
 Frame = +2

Query: 31  PRFTRTPVDQTGVSGGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLR 90
           P  T    + T   G  A   C A G P P I W +  + +         F +G+  + +
Sbjct: 77  PAITVKSNNITVFEGHSAILHCVAKGSPSPDIAWYRDSQPILPNARRYTLFKNGTMKIRQ 256

Query: 91  IQPLRTPRDEAIYECVASNNVGEISVSTRLTVLREDQIPRGFPTIDMGPQLKVVERTRTA 150
           +       D  +Y CVA+N  G ++ ++    LR     R          +K     R +
Sbjct: 257 V----FMEDNGMYACVANNTAGPLAGTSSFA-LRTMHWRR----------MKTSTW*RPS 391

Query: 151 TMLCAASGNPDPEITW 166
           + LC A   P P + W
Sbjct: 392 SSLCVA---PAPTLPW 430

 Score = 31.6 bits (70), Expect = 2.5,   Method: Compositional matrix adjust.
 Identities = 22/94 (23%), Positives = 39/94 (41%), Gaps = 9/94 (9%)
 Frame = +2

Query: 245 FSIPPTNHEIMPGGSVNITCVAVGSPMPYVKWMLGAEDLTP---------EDDMPIGRNV 295
            ++   N  +  G S  + CVA GSP P + W   ++ + P            M I +  
Sbjct: 83  ITVKSNNITVFEGHSAILHCVAKGSPSPDIAWYRDSQPILPNARRYTLFKNGTMKIRQVF 262

Query: 296 LELNDVRQSANYTCVAMSTLGVIEAIAQITVKAL 329
           +E N +     Y CVA +T G +   +   ++ +
Sbjct: 263 MEDNGM-----YACVANNTAGPLAGTSSFALRTM 349
>30215
          Length = 389

 Score = 48.5 bits (114), Expect = 2e-05,   Method: Composition-based stats.
 Identities = 21/52 (40%), Positives = 30/52 (57%)
 Frame = +1

Query: 1449 VFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDQYQFCYRAALEYL 1500
            V + +   L R+     +D+F  V  +R QR  M+QT+DQY FCY A +E L
Sbjct: 1    VLMAVDTALARIETGDELDLFDIVSEMRQQRYGMIQTQDQYLFCYTACMEAL 156

 Score = 46.6 bits (109), Expect = 8e-05,   Method: Composition-based stats.
 Identities = 20/51 (39%), Positives = 33/51 (64%)
 Frame = +1

Query: 1159 FIVIDAMLERIKHEKTVDIYGHVTLMRAQRNYMVQTEDQYIFIHDALLEAV 1209
             + +D  L RI+    +D++  V+ MR QR  M+QT+DQY+F + A +EA+
Sbjct: 4    LMAVDTALARIETGDELDLFDIVSEMRQQRYGMIQTQDQYLFCYTACMEAL 156
>11855
          Length = 1574

 Score = 46.6 bits (109), Expect = 8e-05,   Method: Compositional matrix adjust.
 Identities = 56/208 (26%), Positives = 81/208 (38%), Gaps = 32/208 (15%)
 Frame = +1

Query: 56  GDPRPKIVWNKKGKKVSNQRFEVIEFD---------DGSGSVLRIQPLR--------TPR 98
           G P P I W K G +++   +E ++ +         D     LR+   +        T +
Sbjct: 1   GSPVPTIHWLKDGVRLTQSTYETVDDESALYEDLASDPGQPRLRLSSTKSRLYLDCPTSQ 180

Query: 99  DEAIYECVASNNVGEISVSTRLTVLREDQIP----------RGFPT-IDMGPQLKVVERT 147
           DE  Y CVA         ST + V      P          RG P  + M    ++   T
Sbjct: 181 DEGEYTCVAETPFKRRVQSTIVKVDTRHYSPDVTCMSKRGSRGEPARVYMWTVSRLELET 360

Query: 148 RTATMLCAASGNPDPEITWF---KDFLPVDTSNNNGRIKQLRSESIGGTPIRGALQIEQ- 203
            T  + C ASG P+P ITW+    + LP    +N+G+             + G L I   
Sbjct: 361 TTVQLFCRASGYPEPTITWYDGRNNSLP----DNSGQFS---------IAVNGDLIIRDI 501

Query: 204 SEESDQGKYECVATNSAGTRYSAPANLY 231
           S   + G Y CVA N  G+ +S  A LY
Sbjct: 502 SWSENMGVYRCVAENELGS-HSVQAFLY 582

 Score = 32.3 bits (72), Expect = 1.4,   Method: Compositional matrix adjust.
 Identities = 26/105 (24%), Positives = 41/105 (39%), Gaps = 1/105 (0%)
 Frame = +1

Query: 30  PPRFTRTPVDQTGVSGGVASFICQATGDPRPKIVW-NKKGKKVSNQRFEVIEFDDGSGSV 88
           P R     V +  +        C+A+G P P I W + +   + +      +F       
Sbjct: 313 PARVYMWTVSRLELETTTVQLFCRASGYPEPTITWYDGRNNSLPDNSG---QFSIAVNGD 483

Query: 89  LRIQPLRTPRDEAIYECVASNNVGEISVSTRLTVLREDQIPRGFP 133
           L I+ +    +  +Y CVA N +G  SV   L     D+ P  FP
Sbjct: 484 LIIRDISWSENMGVYRCVAENELGSHSVQAFLYPTTLDE-PDSFP 615
>07196
          Length = 849

 Score = 45.1 bits (105), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 31/123 (25%), Positives = 55/123 (44%), Gaps = 1/123 (0%)
 Frame = -1

Query: 1376 PQYILREFKVTDARDGQSRTVRQFQFTDWPEQG-VPKSGEGFIDFIGQVHKTKEQFGQDG 1434
            P YI+REF +   +       +     +WP+   V  S    ++      KT +     G
Sbjct: 744  PGYIVREFILESIQYDYIFMTKVVTVLEWPDFSPVQHSVFSMVELTVDWLKTNDI----G 577

Query: 1435 PISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDQYQFCYR 1494
            P+ V    G  RTG F  L  + +++  +  VD++Q  K+   +RP ++ + +  QF Y 
Sbjct: 576  PVIVMDKYGGVRTGRFCGLWALRDQLLMDKAVDVYQLAKLYHLKRPGIIGSLEDLQFLYE 397

Query: 1495 AAL 1497
            A +
Sbjct: 396  AMV 388

 Score = 43.9 bits (102), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 37/147 (25%), Positives = 63/147 (42%), Gaps = 4/147 (2%)
 Frame = -1

Query: 1064 YWPSRGTETH---GLVQVTLLD-TVELATYCVRTFALYKNGSSEKREVRQFQFTAWPDHG 1119
            +WP RG       G  ++++ D T E   Y VR F L           +      WPD  
Sbjct: 825  FWPERGEIVEVDAGNFKLSMRDETEEHPGYIVREFILESIQYDYIFMTKVVTVLEWPDFS 646

Query: 1120 VPEHPTPFLAFLRRVKTCNPPDAGPMVVHCSAGVGRTGCFIVIDAMLERIKHEKTVDIYG 1179
              +H   F      V      D GP++V    G  RTG F  + A+ +++  +K VD+Y 
Sbjct: 645  PVQHSV-FSMVELTVDWLKTNDIGPVIVMDKYGGVRTGRFCGLWALRDQLLMDKAVDVYQ 469

Query: 1180 HVTLMRAQRNYMVQTEDQYIFIHDALL 1206
               L   +R  ++ + +   F+++A++
Sbjct: 468  LAKLYHLKRPGIIGSLEDLQFLYEAMV 388
>20110
          Length = 820

 Score = 44.3 bits (103), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 37/134 (27%), Positives = 57/134 (42%), Gaps = 13/134 (9%)
 Frame = -1

Query: 99  DEAIYECVASNNVGEISVSTRLTVLREDQIPR--GFPTIDMGPQLK--------VVERTR 148
           D  IY C           + R+T +  ++ P   G  T+ + P +K         +E+ +
Sbjct: 646 DAGIYTC-----------TVRITAVSYEEWPTKIGNLTVQVPPSIKPGDTTAVLQIEQGQ 500

Query: 149 TATMLCAASGNPDPEITWFKD---FLPVDTSNNNGRIKQLRSESIGGTPIRGALQIEQSE 205
            +T++CAASG P P ITW +    FLP+        + Q RS +         L +    
Sbjct: 499 NSTLVCAASGIPAPNITWTRSDGGFLPIG-------VAQFRSAT---------LPMNNVT 368

Query: 206 ESDQGKYECVATNS 219
             D G Y CVA N+
Sbjct: 367 VRDMGVYRCVADNN 326

 Score = 36.6 bits (83), Expect(2) = 0.001,   Method: Compositional matrix adjust.
 Identities = 27/88 (30%), Positives = 39/88 (44%), Gaps = 4/88 (4%)
 Frame = -1

Query: 28  ETPPRFTRTPVDQTGV----SGGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDD 83
           + PP     P D T V     G  ++ +C A+G P P I W +     S+  F  I    
Sbjct: 562 QVPPSIK--PGDTTAVLQIEQGQNSTLVCAASGIPAPNITWTR-----SDGGFLPIGVAQ 404

Query: 84  GSGSVLRIQPLRTPRDEAIYECVASNNV 111
              + L +  + T RD  +Y CVA NN+
Sbjct: 403 FRSATLPMNNV-TVRDMGVYRCVADNNI 323

 Score = 25.4 bits (54), Expect(2) = 0.001,   Method: Compositional matrix adjust.
 Identities = 11/33 (33%), Positives = 17/33 (51%)
 Frame = -3

Query: 150 ATMLCAASGNPDPEITWFKDFLPVDTSNNNGRI 182
           A + C   G+P+P +TW       + + NNGR 
Sbjct: 221 ANLECIVKGHPEPTVTW-------EMAINNGRF 144
>36498
          Length = 478

 Score = 31.2 bits (69), Expect(2) = 0.002,   Method: Compositional matrix adjust.
 Identities = 29/101 (28%), Positives = 50/101 (49%), Gaps = 2/101 (1%)
 Frame = +3

Query: 70  KVSNQRFEVI-EFDDGSGSV-LRIQPLRTPRDEAIYECVASNNVGEISVSTRLTVLREDQ 127
           ++  +R +V+ E++   G+  LR  P+ +  D   Y CVA N  G    +  LTV R   
Sbjct: 168 RLRPRRSDVLPEYEPAPGTAGLRFDPV-SEGDAGRYVCVARNERGITEENVDLTVTRTGV 344

Query: 128 IPRGFPTIDMGPQLKVVERTRTATMLCAASGNPDPEITWFK 168
            P+    ID GP  +++   ++  + C+A G  +P I W +
Sbjct: 345 APQ--VNID-GPGRQMLVDGQSVELSCSARGLRNPLIRWRR 458

 Score = 29.6 bits (65), Expect(2) = 0.002,   Method: Composition-based stats.
 Identities = 14/40 (35%), Positives = 19/40 (47%), Gaps = 1/40 (2%)
 Frame = +1

Query: 28 ETPPRFTRTPVDQ-TGVSGGVASFICQATGDPRPKIVWNK 66
          + PP  T TP  + T + G      C A GDP P + W +
Sbjct: 43 QGPPTVTVTPGTRITALVGDRVDIECVAEGDPTPTVFWRR 162

 Score = 29.6 bits (65), Expect(2) = 0.13,   Method: Compositional matrix adjust.
 Identities = 21/83 (25%), Positives = 31/83 (37%)
 Frame = +3

Query: 194 PIRGALQIEQSEESDQGKYECVATNSAGTRYSAPANLYXXXXXXXXXXXXXFSIPPTNHE 253
           P    L+ +   E D G+Y CVA N  G       N+                  P    
Sbjct: 216 PGTAGLRFDPVSEGDAGRYVCVARNERGI---TEENVDLTVTRTGVAPQVNID-GPGRQM 383

Query: 254 IMPGGSVNITCVAVGSPMPYVKW 276
           ++ G SV ++C A G   P ++W
Sbjct: 384 LVDGQSVELSCSARGLRNPLIRW 452

 Score = 24.6 bits (52), Expect(2) = 0.13,   Method: Composition-based stats.
 Identities = 13/59 (22%), Positives = 26/59 (44%), Gaps = 1/59 (1%)
 Frame = +1

Query: 109 NNVGEISVSTRLTVLREDQIPRGFPTIDMGPQLKVVERT-RTATMLCAASGNPDPEITW 166
           N  G ++++  L +       +G PT+ + P  ++         + C A G+P P + W
Sbjct: 1   NAAGTVTLTASLVI-------QGPPTVTVTPGTRITALVGDRVDIECVAEGDPTPTVFW 156
>25766
          Length = 469

 Score = 40.0 bits (92), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 25/80 (31%), Positives = 32/80 (40%)
 Frame = +1

Query: 197 GALQIEQSEESDQGKYECVATNSAGTRYSAPANLYXXXXXXXXXXXXXFSIPPTNHEIMP 256
           G LQI +   +D G+Y CV T+S G      A L               S+   N     
Sbjct: 61  GILQIPRVTAADAGRYRCVITSSEGITSEGFATL-------RISSPPVVSVKQRNENRQV 219

Query: 257 GGSVNITCVAVGSPMPYVKW 276
           G SV   C   G P+P V+W
Sbjct: 220 GSSVKFHCDVSGDPVPQVRW 279
>07945
          Length = 2023

 Score = 38.1 bits (87), Expect = 0.024,   Method: Compositional matrix adjust.
 Identities = 32/101 (31%), Positives = 46/101 (45%), Gaps = 5/101 (4%)
 Frame = -3

Query: 505  IGDGPLSSDIQVITQTGVPGQPLNFKAEPESETSILLSWTPPR---SDTIASY--ELVYR 559
            + D  L+S  +     G P  P    A   +  S+ LSW PPR   SDTI +Y  E    
Sbjct: 1760 VTDHALNSKDKPAPPRGKPCPPSQPVATDITHNSLTLSWQPPRRNSSDTIYAYTVEKTXP 1581

Query: 560  DGDQGEEQRITIEPGTSYRLQGLKPNSLYYFRLSARSPQGL 600
               +G     T   G  Y+++ L P+S Y FR+ A +  G+
Sbjct: 1580 SDXKGWTIVTTSCQGNQYQVKKLSPSSQYVFRVRAENIHGV 1458

 Score = 37.0 bits (84), Expect = 0.061,   Method: Compositional matrix adjust.
 Identities = 28/92 (30%), Positives = 40/92 (43%), Gaps = 4/92 (4%)
 Frame = -3

Query: 327  KALPKPPGTPVVTESTATSITLTWD----SGNPEPVSYYIIQHKPKNSEEPYKEIDGIAT 382
            +  P PP  PV T+ T  S+TL+W     + +    +Y + +  P + +           
Sbjct: 1715 RGKPCPPSQPVATDITHNSLTLSWQPPRRNSSDTIYAYTVEKTXPSDXKGWTIVTTSCQG 1536

Query: 383  TRYSVAGLSPYSDYEFRVVAVNNIGRGPASEP 414
             +Y V  LSP S Y FRV A N  G    S P
Sbjct: 1535 NQYQVKKLSPSSQYVFRVRAENIHGVSKGSRP 1440
>17530
          Length = 503

 Score = 37.7 bits (86), Expect = 0.035,   Method: Compositional matrix adjust.
 Identities = 34/117 (29%), Positives = 49/117 (41%), Gaps = 1/117 (0%)
 Frame = +2

Query: 115 SVSTRLTVLREDQIPRGFPTIDMGPQLKVVERTRTATMLCAASG-NPDPEITWFKDFLPV 173
           S S  LTVL    +P G P+I       V E  +     C++SG NP P ITW K+   V
Sbjct: 23  SASANLTVL----LPPGPPSITSDITGDVFEEGQRVRFTCSSSGGNPPPTITWTKN--GV 184

Query: 174 DTSNNNGRIKQLRSESIGGTPIRGALQIEQSEESDQGKYECVATNSAGTRYSAPANL 230
              N   +I   ++ + GG+  R  + +       Q  Y C   N      S  A++
Sbjct: 185 QLINGVQQIGVGQTSTSGGS-TRNTVSVVMDHSDHQANYTCFVYNQVNINSSLTASV 352

 Score = 30.8 bits (68), Expect = 4.9,   Method: Compositional matrix adjust.
 Identities = 37/137 (27%), Positives = 48/137 (35%), Gaps = 6/137 (4%)
 Frame = +2

Query: 30  PPRFTRTPVDQTGVSGGVASFICQATG-DPRPKIVWNKKGKKVSN--QRFEVIEFDDGSG 86
           PP  T          G    F C ++G +P P I W K G ++ N  Q+  V +     G
Sbjct: 62  PPSITSDITGDVFEEGQRVRFTCSSSGGNPPPTITWTKNGVQLINGVQQIGVGQTSTSGG 241

Query: 87  SVLRIQPLRTPRD--EAIYECVASNNVGEISVSTRLTVLREDQIPRGFPTIDMGP-QLKV 143
           S      +       +A Y C   N V   S  T   VL      R  P I   P    +
Sbjct: 242 STRNTVSVVMDHSDHQANYTCFVYNQVNINSSLTASVVLNV----RYSPIITFEPFSPYI 409

Query: 144 VERTRTATMLCAASGNP 160
           V   R A + C    NP
Sbjct: 410 VRLDRPANITCQVDANP 460
>25697
          Length = 470

 Score = 36.6 bits (83), Expect = 0.069,   Method: Compositional matrix adjust.
 Identities = 22/80 (27%), Positives = 40/80 (50%), Gaps = 3/80 (3%)
 Frame = +1

Query: 1418 DFIGQVHKTKEQFGQDGP---ISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKM 1474
            D +G      +   +D P   ++VHC AG+GR  V + ++++   M+YE  V++ +    
Sbjct: 184  DVVGNWFNLLKASFKDDPGCCVAVHCVAGLGRAPVLVAIALMEAGMKYEDAVELIR---- 351

Query: 1475 LRTQRPAMVQTEDQYQFCYR 1494
             R +R A+   +  Y   YR
Sbjct: 352  -RKRRGAINSKQLSYLQHYR 408

 Score = 31.2 bits (69), Expect = 3.4,   Method: Compositional matrix adjust.
 Identities = 24/79 (30%), Positives = 32/79 (40%), Gaps = 2/79 (2%)
 Frame = +1

Query: 1101 SSEKREVRQFQFTAWP-DHGVPEHPTPFLAFLRRVKTCNPPDAGPMV-VHCSAGVGRTGC 1158
            S EK E        W  D G P        +   +K     D G  V VHC AG+GR   
Sbjct: 109  SKEKLETEGIDVMDWQFDDGSPPPKDVVGNWFNLLKASFKDDPGCCVAVHCVAGLGRAPV 288

Query: 1159 FIVIDAMLERIKHEKTVDI 1177
             + I  M   +K+E  V++
Sbjct: 289  LVAIALMEAGMKYEDAVEL 345
>18345
          Length = 461

 Score = 36.6 bits (83), Expect = 0.079,   Method: Compositional matrix adjust.
 Identities = 24/79 (30%), Positives = 40/79 (50%), Gaps = 1/79 (1%)
 Frame = +1

Query: 45  GGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAIYE 104
           G  A+ +C  TG P P + W K+  +  + + E +     +G VL +  +    D+ IYE
Sbjct: 157 GDTATLVCNVTGVPSPDVTWYKRNTRQLDAQKERV---GSTGPVLVMYNVTRHCDD-IYE 324

Query: 105 CVASNNV-GEISVSTRLTV 122
           C A N V   ++ + R+TV
Sbjct: 325 CYADNGVPPAVTKAIRVTV 381

 Score = 33.5 bits (75), Expect = 0.62,   Method: Compositional matrix adjust.
 Identities = 21/71 (29%), Positives = 33/71 (46%), Gaps = 1/71 (1%)
 Frame = +1

Query: 149 TATMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGGT-PIRGALQIEQSEES 207
           TAT++C  +G P P++TW+K          N R    + E +G T P+     + +  + 
Sbjct: 163 TATLVCNVTGVPSPDVTWYK---------RNTRQLDAQKERVGSTGPVLVMYNVTRHCDD 315

Query: 208 DQGKYECVATN 218
               YEC A N
Sbjct: 316 ---IYECYADN 339
>20244
          Length = 452

 Score = 32.3 bits (72), Expect(2) = 0.19,   Method: Composition-based stats.
 Identities = 12/27 (44%), Positives = 18/27 (66%)
 Frame = -1

Query: 41  TGVSGGVASFICQATGDPRPKIVWNKK 67
           + ++GG+A   C ATG+P P I W+ K
Sbjct: 410 SDLNGGIAVLRCFATGNPAPNITWSLK 330

 Score = 21.6 bits (44), Expect(2) = 0.19,   Method: Compositional matrix adjust.
 Identities = 21/68 (30%), Positives = 29/68 (42%), Gaps = 4/68 (5%)
 Frame = -2

Query: 103 YECV-ASNNVGEI---SVSTRLTVLREDQIPRGFPTIDMGPQLKVVERTRTATMLCAASG 158
           Y C+ ASN +GE     V  ++TV  E         I + PQ      + T    C+  G
Sbjct: 241 YLCLLASNGLGEPVRREVELQVTVNAEA-------VIGLDPQNSYTPGS-TIAFNCSVQG 86

Query: 159 NPDPEITW 166
            P P +TW
Sbjct: 85  YPTPNVTW 62

 Score = 30.8 bits (68), Expect = 4.2,   Method: Composition-based stats.
 Identities = 12/27 (44%), Positives = 17/27 (62%)
 Frame = -1

Query: 150 ATMLCAASGNPDPEITWFKDFLPVDTS 176
           A + C A+GNP P ITW    + +DT+
Sbjct: 389 AVLRCFATGNPAPNITWSLKNVVIDTT 309
>14057
          Length = 1377

 Score = 35.0 bits (79), Expect = 0.23,   Method: Compositional matrix adjust.
 Identities = 12/35 (34%), Positives = 24/35 (68%)
 Frame = +2

Query: 1436 ISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQ 1470
            ++VHC AG+GR  V + ++++   M+YE  V++ +
Sbjct: 956  VAVHCVAGLGRAPVLVAIALMEAGMKYEDAVELIR 1060
>38127
          Length = 860

 Score = 34.3 bits (77), Expect = 0.36,   Method: Compositional matrix adjust.
 Identities = 19/65 (29%), Positives = 31/65 (47%), Gaps = 1/65 (1%)
 Frame = -1

Query: 154 CAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGGTPIRGA-LQIEQSEESDQGKY 212
           C   G P P ++W+ D + +     + R     + S  G  I GA L IE+ +  D G+Y
Sbjct: 620 CKVLGYPKPVVSWYMDNVEI-VDGADSRYSLKPANSYDGASIEGAKLVIEEVQFDDAGEY 444

Query: 213 ECVAT 217
            C++ 
Sbjct: 443 TCMSN 429
>25455
          Length = 444

 Score = 34.3 bits (77), Expect = 0.44,   Method: Compositional matrix adjust.
 Identities = 22/66 (33%), Positives = 32/66 (48%), Gaps = 1/66 (1%)
 Frame = +1

Query: 103 YECVASNNVGEISVSTRLTVLREDQIP-RGFPTIDMGPQLKVVERTRTATMLCAASGNPD 161
           Y C A + V  I+       LRE ++  +  P+  + PQ+  VE   TA + C A+  PD
Sbjct: 1   YRCWAESTVHHINFP-----LREMRVVVQSAPSWVVAPQVTEVEVGETAEITCNATAIPD 165

Query: 162 PEITWF 167
           P   WF
Sbjct: 166 PVTNWF 183
>13135
          Length = 849

 Score = 33.9 bits (76), Expect = 0.47,   Method: Compositional matrix adjust.
 Identities = 29/119 (24%), Positives = 48/119 (40%), Gaps = 4/119 (3%)
 Frame = -1

Query: 52  CQATGDPRPKIVWNK-KGKKVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAIYECVASNN 110
           C A+G P P + W +  G+ + +   E +E D        + P   P    IY+C +SN+
Sbjct: 315 CHASGRPTPSVKWTRMAGELLPSGGREHLESD-------LVIPQLKPEHAGIYKCSSSNS 157

Query: 111 VGEISVSTRLTVLREDQIPRGFPTIDMGPQLKVVERTRTATMLCAASGNPDP---EITW 166
            G    + R+TV          P +     +    +     ++C   G P P   +ITW
Sbjct: 156 AGSDFRNIRVTV-------NFAPVLSSANTVVQQAQGYVKELVCVVKGYPTPKADDITW 1
>12764
          Length = 1055

 Score = 33.9 bits (76), Expect = 0.54,   Method: Compositional matrix adjust.
 Identities = 19/72 (26%), Positives = 36/72 (50%), Gaps = 1/72 (1%)
 Frame = +1

Query: 245 FSIPPTNHEIMPGGSVNITCVAVGSPMPY-VKWMLGAEDLTPEDDMPIGRNVLELNDVRQ 303
            S+ P   +   G ++++TC+  G+P+P+ V+W    E+ T      +    L L+D   
Sbjct: 235 VSVTPDTQQREEGLNLDLTCITQGNPLPFLVEWRQEGENTTLATGNTLTLTNLSLSD--- 405

Query: 304 SANYTCVAMSTL 315
           +  YTC   +T+
Sbjct: 406 TGTYTCTGYNTV 441
>32888
          Length = 418

 Score = 28.5 bits (62), Expect(2) = 0.82,   Method: Compositional matrix adjust.
 Identities = 9/22 (40%), Positives = 15/22 (68%)
 Frame = -3

Query: 148 RTATMLCAASGNPDPEITWFKD 169
           +T  + C A G P P++TW+K+
Sbjct: 230 QTVRLDCRAKGKPSPKVTWYKN 165

 Score = 23.5 bits (49), Expect(2) = 0.82,   Method: Composition-based stats.
 Identities = 8/23 (34%), Positives = 13/23 (56%)
 Frame = -2

Query: 199 LQIEQSEESDQGKYECVATNSAG 221
           L I+     D+G Y C+ +N+ G
Sbjct: 114 LTIKSLGAEDKGNYTCIVSNTEG 46
>37675
          Length = 741

 Score = 32.3 bits (72), Expect = 1.3,   Method: Composition-based stats.
 Identities = 21/90 (23%), Positives = 36/90 (40%)
 Frame = +2

Query: 127 QIPRGFPTIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLR 186
           Q+P   P + + P   +      A M C A G P P I+W  + +P+     +  ++   
Sbjct: 62  QMP---PVVKVSPHSLIYPARLNAKMKCHAEGVPKPTISWLFNNVPISEDPQHYDLESAN 232

Query: 187 SESIGGTPIRGALQIEQSEESDQGKYECVA 216
                       L +  + + D G Y+CVA
Sbjct: 233 E----------LLVVYNAGDQDTGAYKCVA 292
>25554
          Length = 435

 Score = 32.0 bits (71), Expect = 1.9,   Method: Compositional matrix adjust.
 Identities = 17/57 (29%), Positives = 25/57 (43%)
 Frame = -3

Query: 404 NNIGRGPASEPVLTQTSEQAPSSAPRDVQARMLSSTTILVQWKEPEEPNGQIQGYRV 460
           NNI     ++    QT    P+     +      S  I V W++P+ PNG I GY +
Sbjct: 430 NNINSDVRTDRFRVQTK---PAGVVSSLTLNKFGSRWINVTWRKPDNPNGNISGYTI 269
>30103
          Length = 341

 Score = 30.8 bits (68), Expect = 4.4,   Method: Composition-based stats.
 Identities = 18/83 (21%), Positives = 39/83 (46%), Gaps = 2/83 (2%)
 Frame = +1

Query: 430 DVQARMLSSTTILVQWKEP--EEPNGQIQGYRVYYTMDPTQHVNNWMKHNVADSQITTIG 487
           ++  +  + + +L++W+ P   + NG +Q Y+V Y    ++  +       +      + 
Sbjct: 1   NLSLKFSNDSLVLLKWRPPAARQKNGVLQSYKVQYRRKGSRRGDVCSVITPSQDHHFFLT 180

Query: 488 NLVPQKTYSVKVLAFTSIGDGPL 510
           ++   +TY V+V A T  G GP 
Sbjct: 181 DVTSGQTYKVRVAAMTVNGTGPF 249
>08005
          Length = 593

 Score = 30.4 bits (67), Expect = 5.1,   Method: Composition-based stats.
 Identities = 18/60 (30%), Positives = 23/60 (38%), Gaps = 2/60 (3%)
 Frame = +2

Query: 1305 RQQKAYIATQGPLA--ETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWPAERSARY 1362
            R +  Y +T GPLA         + LW   S I V    +R   R      WP    AR+
Sbjct: 62   RHRLGYASTAGPLAGYRPFRQHRQSLWRAASAICVDAISMRTRSRSTVRPLWPPPSPARF 241
>34811
          Length = 613

 Score = 30.4 bits (67), Expect = 5.3,   Method: Compositional matrix adjust.
 Identities = 11/28 (39%), Positives = 15/28 (53%)
 Frame = +3

Query: 142 KVVERTRTATMLCAASGNPDPEITWFKD 169
           + +  T+  T+ C   G P P I WFKD
Sbjct: 507 RTISNTQPLTLTCRGQGRPQPIIEWFKD 590
>27666
          Length = 873

 Score = 29.6 bits (65), Expect = 9.6,   Method: Compositional matrix adjust.
 Identities = 17/67 (25%), Positives = 28/67 (41%), Gaps = 3/67 (4%)
 Frame = +1

Query: 48  ASFICQATGDPRPKIVWNK---KGKKVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAIYE 104
           +S +C +TG P P I W +   +       +F   E      +V  +          +Y 
Sbjct: 571 SSLVCSSTGIPAPNITWTRLDGRALPTGYSQFRGRELPLNGATVDHM---------GVYR 723

Query: 105 CVASNNV 111
           CVA+NN+
Sbjct: 724 CVANNNI 744
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|20806532|ref|NP_035863.1| cold shock domain protein A
short isoform [Mus musculus]
         (292 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

11798                                                                 124   4e-29
00661                                                                  74   1e-13
23204                                                                  70   7e-13
35001                                                                  28   4.0  
>11798
          Length = 1642

 Score =  124 bits (312), Expect = 4e-29,   Method: Compositional matrix adjust.
 Identities = 58/78 (74%), Positives = 65/78 (83%)
 Frame = +2

Query: 75  EKKVLATKVLGTVKWFNVRNGYGFINRNDTKEDVFVHQTAIKKNNPRKYLRSVGDGETVE 134
           EKKV+A K+ GTVKWFNV++GYGFINR+DT EDVFVHQTAI KNNP+KYLRSVGD E VE
Sbjct: 242 EKKVIAEKIKGTVKWFNVKSGYGFINRDDTNEDVFVHQTAIVKNNPKKYLRSVGDNEEVE 421

Query: 135 FDVVEGEKGAEAANVTGP 152
           FDVVEGEKG +      P
Sbjct: 422 FDVVEGEKGTKRPTSLAP 475

 Score = 40.0 bits (92), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 18/24 (75%), Positives = 21/24 (87%)
 Frame = +1

Query: 142 KGAEAANVTGPDGVPVEGSRYAAD 165
           KG EAANVTGP+G  V+GS+YAAD
Sbjct: 442 KGNEAANVTGPNGTNVQGSKYAAD 513
>00661
          Length = 2118

 Score = 73.6 bits (179), Expect = 1e-13,   Method: Compositional matrix adjust.
 Identities = 38/76 (50%), Positives = 45/76 (59%)
 Frame = +3

Query: 85  GTVKWFNVRNGYGFINRNDTKEDVFVHQTAIKKNNPRKYLRSVGDGETVEFDVVEGEKGA 144
           G VKWFNV  G+GFI  +D   DVFVHQ+AI K+      RS+GD E VEF  V   KG 
Sbjct: 24  GKVKWFNVAKGWGFITPDDGTTDVFVHQSAIHKSG----FRSLGDDEVVEFHTVTSAKGY 191

Query: 145 EAANVTGPDGVPVEGS 160
           EA +V+   G    GS
Sbjct: 192 EARDVSAVGGAECRGS 239
>23204
          Length = 1566

 Score = 70.5 bits (171), Expect = 7e-13,   Method: Compositional matrix adjust.
 Identities = 37/83 (44%), Positives = 46/83 (55%)
 Frame = +1

Query: 78  VLATKVLGTVKWFNVRNGYGFINRNDTKEDVFVHQTAIKKNNPRKYLRSVGDGETVEFDV 137
           V   +  G  KWFNV  G+GFI  +D  +DVFVHQ+ I K       RS+G+GE VEF+ 
Sbjct: 160 VWWGRRRGYCKWFNVAKGWGFITPDDQTQDVFVHQSTIYKAG----FRSLGEGEIVEFES 327

Query: 138 VEGEKGAEAANVTGPDGVPVEGS 160
              +KG EA  V G  G    GS
Sbjct: 328 KPSDKGVEAVFVCGVGGAECRGS 396
>35001
          Length = 942

 Score = 28.1 bits (61), Expect = 4.0,   Method: Compositional matrix adjust.
 Identities = 12/47 (25%), Positives = 24/47 (51%)
 Frame = +1

Query: 91  NVRNGYGFINRNDTKEDVFVHQTAIKKNNPRKYLRSVGDGETVEFDV 137
           +++  +GFI R D   ++F H +  + N     +  +  G+ VEF +
Sbjct: 712 SMKESFGFIERADVVREIFFHYSEFRGN-----IEDLELGDDVEFSI 837
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|21450183|ref|NP_659062.1| solute carrier family 24
(sodium/potassium/calcium exchanger), member 1 [Mus musculus]
         (1130 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

21041                                                                 126   4e-29
31357                                                                  40   0.004
28131                                                                  30   4.7  
>21041
          Length = 926

 Score =  126 bits (317), Expect = 4e-29,   Method: Composition-based stats.
 Identities = 66/175 (37%), Positives = 101/175 (57%), Gaps = 1/175 (0%)
 Frame = +3

Query: 947  PIVFPLWLTIPDVRRQESRKFFVITFLGSIIWIAMFSYLMVWWAHQVGETIGISEEIMGL 1006
            PI +    T+PD R+ + RK++  +FL S+IWI+ +SY MVW    +G T+ I + +MGL
Sbjct: 195  PIHYLCKKTVPDCRQDKFRKWYPFSFLISMIWISFYSYFMVWMITVIGSTLAIPDTVMGL 374

Query: 1007 TILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPVPWLL-FSLINALQPV 1065
            T +AAG S+PD I S+ V ++G GDMAVS+++GSN+FDI V L +PW +  ++I     V
Sbjct: 375  TFVAAGVSVPDAIXSIAVIKEGFGDMAVSNAIGSNVFDILVCLGLPWFIQTAIIKPGSHV 554

Query: 1066 PVSSNGXXXXXXXXXXXXXXXXXSIASCKWRMNKILGFTMFLLYFVFLVISVMLE 1120
             V S G                 S     W+++K LG  + L Y  F+ ++ + E
Sbjct: 555  NVISKGLVYSTLSLFSTVVFLILSTHLNGWKLDKRLGIILMLWYLFFITLASLYE 719

 Score = 38.9 bits (89), Expect = 0.012,   Method: Composition-based stats.
 Identities = 22/66 (33%), Positives = 35/66 (53%)
 Frame = +3

Query: 443 YFVPALGVITHKLQISEDVAGATFMAAGGSAPELFTSLIGVFISHSNVGIGTIVGSAVFN 502
           + V  + VI   L I + V G TF+AAG S P+   S+  +     ++ +   +GS VF+
Sbjct: 309 FMVWMITVIGSTLAIPDTVMGLTFVAAGVSVPDAIXSIAVIKEGFGDMAVSNAIGSNVFD 488

Query: 503 ILFVIG 508
           IL  +G
Sbjct: 489 ILVCLG 506
>31357
          Length = 442

 Score = 40.4 bits (93), Expect = 0.004,   Method: Composition-based stats.
 Identities = 19/59 (32%), Positives = 36/59 (61%), Gaps = 1/59 (1%)
 Frame = +1

Query: 998  GISEEIMGLTILAAGTSIPDLITSVIVARK-GLGDMAVSSSVGSNIFDITVGLPVPWLL 1055
            G+ + +  +T++A GTS+PDL  S   A++    D ++ +  GSN  ++ +GL V W++
Sbjct: 190  GLKDTVTAITLVALGTSLPDLFASRQAAKQEKYADNSIGNVTGSNSVNVFMGLGVSWII 366
>28131
          Length = 1014

 Score = 30.4 bits (67), Expect = 4.7,   Method: Composition-based stats.
 Identities = 12/36 (33%), Positives = 18/36 (50%)
 Frame = -1

Query: 491 GIGTIVGSAVFNILFVIGTCALFSREILNLTWWPLF 526
           G   + GS +  ++ V G C +F R I +  WW  F
Sbjct: 201 GHNEVTGSTLVRLMHVEGVCVIFRRAITS*HWW*FF 94
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6755925|ref|NP_036038.1| ubiquitin-like 3 [Mus
musculus]
         (117 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

29877                                                                 122   4e-29
08870                                                                  61   9e-11
17528                                                                  29   0.53 
00876                                                                  27   2.6  
05307                                                                  26   3.2  
03951                                                                  26   5.1  
31001                                                                  25   5.9  
11860                                                                  25   7.7  
15210                                                                  25   7.9  
26374                                                                  25   8.4  
>29877
          Length = 636

 Score =  122 bits (306), Expect = 4e-29,   Method: Compositional matrix adjust.
 Identities = 56/81 (69%), Positives = 67/81 (82%)
 Frame = -1

Query: 1   MSSHVPADMINLRLILVSGKTKEFLFSPNDSASDIAKHVYDNWPMDWEEEQVSSPNILRL 60
           M+ H+P D INLRLILVSGKT EFLFSP+DSA++I  HV+ +WP +W +E + S NILRL
Sbjct: 243 MARHIPGDKINLRLILVSGKTHEFLFSPSDSAAEITDHVFCHWPEEWSDELLPSTNILRL 64

Query: 61  IYQGRFLHGNVTLGALKLPFG 81
           IYQGRFLHGNVTL AL+LP G
Sbjct: 63  IYQGRFLHGNVTLAALQLPTG 1
>08870
          Length = 2452

 Score = 61.2 bits (147), Expect = 9e-11,   Method: Compositional matrix adjust.
 Identities = 28/42 (66%), Positives = 35/42 (83%), Gaps = 3/42 (7%)
 Frame = +3

Query: 79  PFGKTTVMHLVARETLPEPNSQGQRNREKTGES---NCCVIL 117
           P GKTTVMHLV+RE LPEPN+QGQ  ++K+GE+   NCCV+L
Sbjct: 3   PTGKTTVMHLVSRENLPEPNNQGQLKKDKSGETGCNNCCVVL 128
>17528
          Length = 459

 Score = 28.9 bits (63), Expect = 0.53,   Method: Compositional matrix adjust.
 Identities = 12/43 (27%), Positives = 21/43 (48%)
 Frame = -2

Query: 38  HVYDNWPMDWEEEQVSSPNILRLIYQGRFLHGNVTLGALKLPF 80
           HV+  WP      Q+S    +R++Y   F   ++   ++ LPF
Sbjct: 251 HVHRGWPSGASNSQLSHSGRVRVLYMSPFCFLSLFFSSMVLPF 123
>00876
          Length = 4275

 Score = 26.6 bits (57), Expect = 2.6,   Method: Composition-based stats.
 Identities = 11/26 (42%), Positives = 14/26 (53%)
 Frame = +3

Query: 55  PNILRLIYQGRFLHGNVTLGALKLPF 80
           PN   +IY GRF +       L+LPF
Sbjct: 630 PNWCHVIYNGRFWYAQKHCTVLQLPF 707
>05307
          Length = 514

 Score = 26.2 bits (56), Expect = 3.2,   Method: Compositional matrix adjust.
 Identities = 19/68 (27%), Positives = 32/68 (47%), Gaps = 3/68 (4%)
 Frame = -3

Query: 8   DMINLRLILVSGKTKEFLFSP---NDSASDIAKHVYDNWPMDWEEEQVSSPNILRLIYQG 64
           +MI+ + +L++ K + FLFSP   N  AS+++ H +   P      +   P     I   
Sbjct: 494 NMIDDQWVLMACKKEYFLFSPNLFNRLASNLSSHDFLMVPTYQPSLRTIHPETTEKIAST 315

Query: 65  RFLHGNVT 72
            F+H   T
Sbjct: 314 HFVHERQT 291
>03951
          Length = 2402

 Score = 25.8 bits (55), Expect = 5.1,   Method: Composition-based stats.
 Identities = 13/27 (48%), Positives = 18/27 (66%), Gaps = 1/27 (3%)
 Frame = +2

Query: 58   LRLIYQGRFL-HGNVTLGALKLPFGKT 83
            + L YQG F+ +  +T+G L LPFG T
Sbjct: 1580 MSL*YQGVFIKYIQLTIGCLFLPFGHT 1660
>31001
          Length = 475

 Score = 25.4 bits (54), Expect = 5.9,   Method: Compositional matrix adjust.
 Identities = 13/39 (33%), Positives = 20/39 (51%)
 Frame = -1

Query: 9   MINLRLILVSGKTKEFLFSPNDSASDIAKHVYDNWPMDW 47
           +INL+      K  E +  PN  A  +AK   DN+ ++W
Sbjct: 397 LINLQ------KWVELIALPNQQAETVAKAAVDNFSLEW 299
>11860
          Length = 944

 Score = 25.0 bits (53), Expect = 7.7,   Method: Compositional matrix adjust.
 Identities = 11/24 (45%), Positives = 17/24 (70%)
 Frame = +3

Query: 8   DMINLRLILVSGKTKEFLFSPNDS 31
           D+++  LI V+GK +  LFSP D+
Sbjct: 384 DVMDNLLIQVTGKKRVVLFSPQDA 455
>15210
          Length = 729

 Score = 25.0 bits (53), Expect = 7.9,   Method: Compositional matrix adjust.
 Identities = 10/18 (55%), Positives = 13/18 (72%)
 Frame = +1

Query: 100 QGQRNREKTGESNCCVIL 117
           +GQR REK GE + CV +
Sbjct: 472 RGQREREKRGEVDVCVCV 525
>26374
          Length = 864

 Score = 25.0 bits (53), Expect = 8.4,   Method: Compositional matrix adjust.
 Identities = 16/48 (33%), Positives = 25/48 (52%)
 Frame = +3

Query: 47  WEEEQVSSPNILRLIYQGRFLHGNVTLGALKLPFGKTTVMHLVARETL 94
           WE++ V+  N LRL      LH ++ L    LP   T V++   ++TL
Sbjct: 144 WEKQNVTILNYLRLF*HCILLHYDMPL--THLPSVLTVVLYYECKQTL 281
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|94681061|ref|NP_001013385.3| protein kinase,
AMP-activated, alpha 1 catalytic subunit [Mus musculus]
         (559 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

15910                                                                 125   4e-29
13066                                                                 115   4e-26
17975                                                                 111   6e-25
12721                                                                 105   3e-23
38560                                                                 102   5e-22
30755                                                                 102   5e-22
21079                                                                 100   2e-21
18484                                                                  99   5e-21
01707                                                                  94   1e-19
09606                                                                  93   2e-19
14420                                                                  92   6e-19
13592                                                                  91   8e-19
01060                                                                  91   9e-19
01392                                                                  89   4e-18
27546                                                                  89   7e-18
21433                                                                  72   9e-18
03240                                                                  87   2e-17
31885                                                                  86   5e-17
14126                                                                  84   1e-16
18921                                                                  84   2e-16
29581                                                                  83   3e-16
00300                                                                  81   9e-16
01718                                                                  79   3e-15
01966                                                                  79   4e-15
06405                                                                  79   7e-15
21808                                                                  78   1e-14
27405                                                                  74   1e-13
04591                                                                  74   1e-13
26560                                                                  70   2e-12
00392                                                                  67   1e-11
19301                                                                  67   2e-11
18663                                                                  64   2e-10
19094                                                                  64   2e-10
20152                                                                  64   2e-10
01756                                                                  63   3e-10
26711                                                                  63   4e-10
13212                                                                  62   4e-10
11780                                                                  62   5e-10
09007                                                                  62   7e-10
11185                                                                  60   2e-09
00486                                                                  60   3e-09
04852                                                                  59   4e-09
14116                                                                  59   4e-09
12786                                                                  59   5e-09
19761                                                                  57   1e-08
14477                                                                  57   1e-08
07940                                                                  55   7e-08
12672                                                                  52   5e-07
28157                                                                  52   5e-07
03508                                                                  52   7e-07
37602                                                                  51   1e-06
00715                                                                  50   2e-06
17300                                                                  49   7e-06
07291                                                                  47   2e-05
04138                                                                  47   2e-05
07836                                                                  47   2e-05
17722                                                                  45   5e-05
08294                                                                  45   6e-05
17253                                                                  45   6e-05
22005                                                                  45   6e-05
29590                                                                  45   1e-04
31489                                                                  44   1e-04
26009                                                                  44   2e-04
18481                                                                  44   2e-04
25019                                                                  44   2e-04
16708                                                                  44   2e-04
28638                                                                  44   3e-04
20640                                                                  43   4e-04
27274                                                                  41   0.001
32000                                                                  40   0.002
31120                                                                  39   0.005
32957                                                                  39   0.008
18996                                                                  38   0.009
36481                                                                  35   0.060
21418                                                                  35   0.11 
36002                                                                  34   0.20 
21800                                                                  33   0.34 
01106                                                                  32   0.54 
29360                                                                  31   1.5  
17516                                                                  30   2.6  
00638                                                                  29   4.0  
>15910
          Length = 1361

 Score =  125 bits (315), Expect = 4e-29,   Method: Compositional matrix adjust.
 Identities = 70/177 (39%), Positives = 101/177 (57%), Gaps = 7/177 (3%)
 Frame = +2

Query: 111 ELFDYICKNGRLDEKESRRLFQQILSGVDYCHRHMVVHRDLKPENVLLDAHMN---AKIA 167
           ELFD I   G+  EK++ R    IL GV Y H + VVHRDLKPEN+L +   +    K+A
Sbjct: 422 ELFDRIVTRGQYTEKDAARAISDILHGVQYIHANGVVHRDLKPENLLYECMTDDSKLKLA 601

Query: 168 DFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAGPEVDIWSSGVILYALLCGTLPFDD 227
           DFGLS ++     + T CG+P Y APEV+ G  Y  P VD+WS GVI Y LLCG  PF  
Sbjct: 602 DFGLSRIIEPEVQMSTVCGTPGYCAPEVLKGDKYT-PSVDMWSVGVIAYILLCGYEPFFA 778

Query: 228 DHVPTLFKKICDGIF-YTPQY---LNPSVISLLKHMLQVDPMKRAAIKDIREHEWFK 280
           ++   +++KI  G + +  +Y   ++ +   +++ +L +DP KR    +     W K
Sbjct: 779 ENEFEMYRKIIKGEYKFDEEYWSEISENAKDVVRKLLVIDPKKRLTATEALRLPWVK 949
>13066
          Length = 551

 Score =  115 bits (288), Expect = 4e-26,   Method: Compositional matrix adjust.
 Identities = 64/166 (38%), Positives = 97/166 (58%), Gaps = 5/166 (3%)
 Frame = +3

Query: 52  KVAVKILNRQKIRSLDVVGKIR-REIQNLKLFRHPHIIKLYQVISTPSDIFMVMEYVSGG 110
           K+A KI++++K   +D V K   RE+  L    HP+II+++ ++      F+ M +   G
Sbjct: 57  KLACKIIDKEK-APVDFVEKFFPRELDLLTKLDHPYIIQIHSILQRXPKNFIFMRFAERG 233

Query: 111 ELFDYICKNGRLDEKESRRLFQQILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFG 170
           +L  YI + G + EK+++  F Q+ + ++Y H + V HRDLK EN+LL +H N K+ADFG
Sbjct: 234 DLLTYIQEVGFVKEKQAKIWFYQMTTALNYLHSYDVAHRDLKCENILLSSHFNVKLADFG 413

Query: 171 L--SNMMSDGE--FLRTSCGSPNYAAPEVISGRLYAGPEVDIWSSG 212
              + +   GE    RT CGS  YAAPE++ G  YA    D WS G
Sbjct: 414 FACACITESGEKYMSRTYCGSAAYAAPEIVYGAPYAPKVADAWSLG 551
>17975
          Length = 449

 Score =  111 bits (278), Expect = 6e-25,   Method: Composition-based stats.
 Identities = 55/134 (41%), Positives = 93/134 (69%), Gaps = 4/134 (2%)
 Frame = +3

Query: 46  HELTGHKVAVKILNRQKIRSLDVVGK--IRREIQNLKLFRHPHIIKLYQVISTPSDIFMV 103
           H  TG KVAVK++++ K   LD V +  + +E++ +KL +HP++++LY+VI T + ++++
Sbjct: 30  HVFTGEKVAVKVIDKTK---LDEVSRSHLFQEVRCMKLVQHPNVVRLYEVIDTQTKLYLI 200

Query: 104 MEYVSGGELFDYICKN-GRLDEKESRRLFQQILSGVDYCHRHMVVHRDLKPENVL-LDAH 161
           +E   GG+++DYI ++ G L+EK ++R F+QI+  + YCH+  VVHRDLKPENV+  +  
Sbjct: 201 LELGDGGDMYDYIMRHSGGLEEKLAKRYFRQIVEAISYCHKLHVVHRDLKPENVVFFEKP 380

Query: 162 MNAKIADFGLSNMM 175
              K+ DFG S  +
Sbjct: 381 GLVKLTDFGFSTCL 422
>12721
          Length = 821

 Score =  105 bits (263), Expect = 3e-23,   Method: Compositional matrix adjust.
 Identities = 69/226 (30%), Positives = 122/226 (53%), Gaps = 6/226 (2%)
 Frame = +1

Query: 50  GHKVAVKI--LNRQKIRSLDVVGKIRREIQNLKLFRHPHIIKLYQVISTPSDIFMVMEYV 107
           G ++AVK   L +Q+ R L     +  E+  ++ + HP+I+++Y       ++++VME++
Sbjct: 160 GRQMAVKKMDLRKQQRREL-----LFNEVVVMRDYHHPNIVEMYNSYLVNDELWVVMEFM 324

Query: 108 SGGELFDYICKNGRLDEKESRRLFQQILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKIA 167
            GG L D I  N R+DE +   + +  L  + + H + V+HRD+K +++LL      K+ 
Sbjct: 325 EGGALTD-IVTNNRMDEVQIATVCRACLKALAFLHANGVIHRDIKSDSILLSHDGKVKLX 501

Query: 168 DFGL-SNMMSDGEFLRTSCGSPNYAAPEVISGRLYAGPEVDIWSSGVILYALLCGTLPFD 226
           DFG  + +  D +  ++  G+P + APEVIS RL  GPEVDIWS G+++  ++    PF 
Sbjct: 502 DFGFCAQVTQDLQKRKSLVGTPYWMAPEVIS-RLPYGPEVDIWSLGIMVMEMIDAEPPFF 678

Query: 227 DDHVPTLFKKICD---GIFYTPQYLNPSVISLLKHMLQVDPMKRAA 269
           ++      ++I D           ++P +   +  ML  DP +RA 
Sbjct: 679 NEPPLQAMRRIRDMPPPKLRNTHKISPRLQGFIDRMLVRDPHQRAT 816
>38560
          Length = 479

 Score =  102 bits (253), Expect = 5e-22,   Method: Compositional matrix adjust.
 Identities = 51/101 (50%), Positives = 62/101 (61%)
 Frame = -3

Query: 181 LRTSCGSPNYAAPEVISGRLYAGPEVDIWSSGVILYALLCGTLPFDDDHVPTLFKKICDG 240
           L T CGSP YAAPE+ISG  Y G E DIWS GV+LYALLCG LPFDD+    L +K    
Sbjct: 414 LTTCCGSPAYAAPELISGLEYLGSEADIWSMGVLLYALLCGYLPFDDEKXSHL*QKNQKR 235

Query: 241 IFYTPQYLNPSVISLLKHMLQVDPMKRAAIKDIREHEWFKQ 281
               P++L+     LL+ MLQ DP  R  I+ + +H W  Q
Sbjct: 234 KDEVPEWLSEDTTKLLEGMLQTDPSHRITIRRLLDHHWLNQ 112
>30755
          Length = 1137

 Score =  102 bits (253), Expect = 5e-22,   Method: Compositional matrix adjust.
 Identities = 59/162 (36%), Positives = 88/162 (54%), Gaps = 6/162 (3%)
 Frame = +2

Query: 124 EKESRRLFQQILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNM-MSDGEFLR 182
           E+ +R    +I+S + Y H   +++RDLK EN+LLD   + K+ADFGL    ++ G   +
Sbjct: 29  EERTRFYGAEIISALGYLHSQGIIYRDLKLENLLLDKDGHIKVADFGLCKEDITYGRTTK 208

Query: 183 TSCGSPNYAAPEVISGRLYAGPEVDIWSSGVILYALLCGTLPFDDDHVPTLFKKICDGIF 242
           T CG+P Y APEV+    Y G  VD W +GV++Y ++CG LPF +     LF  I     
Sbjct: 209 TFCGTPEYLAPEVLDDNDY-GRAVDWWGTGVVMYEMICGRLPFYNRDHDVLFTLILVEDV 385

Query: 243 YTPQYLNPSVISLLKHMLQVDPMKRAA-----IKDIREHEWF 279
             P+ +     SLL  +L  DP  R       +K+I+ H +F
Sbjct: 386 KFPRNITDEAKSLLSGLLAKDPRNRLGGGQDDVKEIQAHPFF 511
>21079
          Length = 878

 Score =  100 bits (248), Expect = 2e-21,   Method: Compositional matrix adjust.
 Identities = 56/144 (38%), Positives = 79/144 (54%), Gaps = 3/144 (2%)
 Frame = +1

Query: 84  HPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNG-RLDEKESRRLFQQILSGVDYCH 142
           HP ++ L+     P  + +VME+V  GELF+ + ++   L E++     +QI SGV Y H
Sbjct: 1   HPKLLMLWDAFEAPRTMVLVMEFVGAGELFERVIRDDFVLTERDCVHFVRQICSGVGYMH 180

Query: 143 RHMVVHRDLKPENVLL--DAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRL 200
              ++H DLKPENVL   D     KI DFGL+     G+ L+   G+P + APEV++   
Sbjct: 181 TQSILHLDLKPENVLCVSDNSNQIKIIDFGLARFYKPGDSLQVLFGTPEFIAPEVVNYD- 357

Query: 201 YAGPEVDIWSSGVILYALLCGTLP 224
                 D+WS GVI Y LL G  P
Sbjct: 358 EINFTTDMWSIGVICYILLSGLSP 429
>18484
          Length = 635

 Score = 98.6 bits (244), Expect = 5e-21,   Method: Compositional matrix adjust.
 Identities = 54/153 (35%), Positives = 86/153 (56%), Gaps = 1/153 (0%)
 Frame = +1

Query: 116 ICKNGRLDEKESRRLFQQILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLS-NM 174
           I + G+  E  +     +I  G+ + H   +++RDLK +NV+LD+  + KIADFG+    
Sbjct: 16  IQQEGKFKEPVAAFYAAEIAVGLFFLHDQGIIYRDLKLDNVMLDSEGHIKIADFGMCKEG 195

Query: 175 MSDGEFLRTSCGSPNYAAPEVISGRLYAGPEVDIWSSGVILYALLCGTLPFDDDHVPTLF 234
           M+     RT CG+P+Y APE++  + Y+   VD W+ GV+L+ +L G  PFD +    LF
Sbjct: 196 MTGDATTRTFCGTPDYIAPEIVLYQPYS-KSVDWWAYGVLLFEMLAGQPPFDGEDEDELF 372

Query: 235 KKICDGIFYTPQYLNPSVISLLKHMLQVDPMKR 267
             I D     P+ ++   +SL K +L  +P KR
Sbjct: 373 SSITDHNVSYPKAMSREAVSLCKGLLMKNPTKR 471
>01707
          Length = 757

 Score = 94.0 bits (232), Expect = 1e-19,   Method: Compositional matrix adjust.
 Identities = 48/149 (32%), Positives = 81/149 (54%), Gaps = 1/149 (0%)
 Frame = +1

Query: 74  REIQNLKLFRHPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQ 133
           REI+ LK  +HP++++L +V      + +V +YV    L +       L E   +R+  Q
Sbjct: 208 REIRMLKQLKHPNLVRLIEVFRRKKRLHLVFDYVDHTLLNELDRYPRGLPEPMVKRIIYQ 387

Query: 134 ILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSD-GEFLRTSCGSPNYAA 192
            L  V++CH++  +HRD+KPEN+L+      K+ DFG + +++  G+       +  Y A
Sbjct: 388 TLLAVNFCHQYNTIHRDVKPENILITRQGQVKLCDFGFARILTGPGDEYTDYVATRWYRA 567

Query: 193 PEVISGRLYAGPEVDIWSSGVILYALLCG 221
           PE++ G    GP VD+W+ G +   LL G
Sbjct: 568 PELLVGDTQYGPPVDVWAIGCVFAELLTG 654
>09606
          Length = 1300

 Score = 93.2 bits (230), Expect = 2e-19,   Method: Compositional matrix adjust.
 Identities = 62/233 (26%), Positives = 109/233 (46%), Gaps = 33/233 (14%)
 Frame = -3

Query: 84  HPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVDYCHR 143
           HP++++ ++   T + +++V+E  +GG L D + ++  L E   R     +++G+ Y H 
Sbjct: 956 HPNVVQFHEWYETSNHLWLVVELCTGGSLADILAQDHHLPETSIRDFGIHLVTGLHYIHS 777

Query: 144 HMVVHRDLKPENVLLDAHMNAKIADFGLS---------------------NMMSDGEFLR 182
             ++  DL+P  VLLD     K ADFGLS                     N+ S  E ++
Sbjct: 776 LGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEAGDQWNIQSAEEMMK 597

Query: 183 T--SCGSPNYAAPEVISGRLYAGPEV--DIWSSGVILYALLCGTLPFDDDHVPTLFKKIC 238
              + GSP Y APEV  G   A P +  D+W+ G + Y +  G  PF  +       K+ 
Sbjct: 596 QVPTSGSPTYMAPEVFQG---AEPSIMSDLWALGCVFYEMFSGHPPFLGETYDITKDKVL 426

Query: 239 DGIFYTPQYL--------NPSVISLLKHMLQVDPMKRAAIKDIREHEWFKQDL 283
           +  F  P+          +P  ++LL+ +LQ D  +R +   + +H +++  L
Sbjct: 425 NKEFPLPKVKGSRLSAKPSPEFLNLLESLLQKDSTRRLSWASLVKHAFWQGGL 267
>14420
          Length = 528

 Score = 92.0 bits (227), Expect = 6e-19,   Method: Composition-based stats.
 Identities = 49/155 (31%), Positives = 90/155 (58%), Gaps = 1/155 (0%)
 Frame = +2

Query: 72  IRREIQNLKLFRHPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLF 131
           I  EI  ++  ++P+I+          ++++VME+++GG L D + +   +DE +   + 
Sbjct: 41  IINEILVMRENQNPNIVNYLDSYLVGEELWVVMEFLAGGSLTDVVTETC-MDEGQIAAVC 217

Query: 132 QQILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLR-TSCGSPNY 190
           ++ L  +++ H + V+HRD+K +N+LL    + K+ DFG    +S  +  R T  G+P +
Sbjct: 218 RECLQALEFLHENQVIHRDIKSDNILLGMDGSVKLTDFGFCAQLSPEQSKRSTMVGTPYW 397

Query: 191 AAPEVISGRLYAGPEVDIWSSGVILYALLCGTLPF 225
            APEV++ + Y GP VDIWS GV+   ++ G  P+
Sbjct: 398 MAPEVVTRKQY-GPTVDIWSLGVMCIEMIEGEPPY 499
>13592
          Length = 980

 Score = 91.3 bits (225), Expect = 8e-19,   Method: Compositional matrix adjust.
 Identities = 73/249 (29%), Positives = 119/249 (47%), Gaps = 17/249 (6%)
 Frame = +2

Query: 49  TGHKVAVKILNRQ--KIRSLDVVGKIRREIQNLKLFRHPHIIKLYQVISTPSDIFMVMEY 106
           TG  +A+K +  Q  + R+L     +  E++ L+  +H ++++ Y +     ++ + ME 
Sbjct: 56  TGELMAMKEIAIQPGETRALK---NVAEELKILEGIKHKNLVRYYGIEVHREELLIFMEL 226

Query: 107 VSGGELFDYICKNGRLDEKESRRLFQQILSGVDYCHRHMVVHRDLKPENV-LLDAHMNAK 165
            S G L   +   G L E  SRR   Q+LSGV   H+H +VHRD+K  N+ L+D   + K
Sbjct: 227 CSEGTLESLVELTGGLPEALSRRFTAQLLSGVAELHKHGIVHRDIKTANIFLVDGSNSLK 406

Query: 166 IADFG-----LSNMMSDGEFLRTSCGSPNYAAPEVIS-------GRLYAGPEVDIWSSGV 213
           + DFG      ++    GE L+   G+  Y APEV +       GRL      DIWS G 
Sbjct: 407 LGDFGSAVKIQAHTTVPGE-LQGYVGTQAYMAPEVFTKTNSDGHGRL-----ADIWSVGC 568

Query: 214 ILYALLCGTLPFD--DDHVPTLFKKICDGIFYTPQYLNPSVISLLKHMLQVDPMKRAAIK 271
           ++  +  G  P+   D +   +FK         P+ L+      + H LQ DP +R +  
Sbjct: 569 VVVEMASGKRPWAQFDSNFQIMFKVGMGEKPQAPESLSQEGHDFIDHCLQHDPKQRLSAI 748

Query: 272 DIREHEWFK 280
           ++ E  + K
Sbjct: 749 ELLEQNFCK 775
>01060
          Length = 1800

 Score = 91.3 bits (225), Expect = 9e-19,   Method: Compositional matrix adjust.
 Identities = 79/267 (29%), Positives = 124/267 (46%), Gaps = 33/267 (12%)
 Frame = +1

Query: 46  HELTGHKVAVKILNRQKIRSLDVVGKIRREIQNLKLFRHPHIIKLYQVISTPSDIFMVME 105
           H  TG K+A+K + R +     V     REI  L+  RH +I+ L  VI     +F+V E
Sbjct: 136 HRATGRKLAMKKI-RLRGSEDGVPSSAIREIAMLRELRHTNIVCLEDVIMEDERLFLVFE 312

Query: 106 YVSGGELFDYICK---NGRLDEKESRRLFQQILSGVDYCHRHMVVHRDLKPENVLLDAHM 162
           ++S  +L  YI K      LD +  +    QI++G+ +CH+  +VHRDLKP+N+L++   
Sbjct: 313 FLSM-DLKMYIDKFPEGVVLDRRLVKSYVFQIVTGIXFCHQRRIVHRDLKPQNLLINHTG 489

Query: 163 NAKIADFGLSNMMSDGEFLRT-SCGSPNYAAPEVISGRLYAGPEVDIWSSGVILYALLCG 221
             KIADFG++   +      T    +  Y APE++ G       VD+WS G I   +L  
Sbjct: 490 AIKIADFGMARTFALPVRAYTHEVVTLWYRAPEILMGASKYSTPVDVWSIGTIFADMLIR 669

Query: 222 TLPF-DDDHVPTLFKKI-------------------CDGIF---------YTPQYLNPSV 252
           T  F  D  +  LFK                      +G+F          T   L+   
Sbjct: 670 TPIFKGDSEIDQLFKIFRIIGTPTEQTWPEFHKLPAFNGMFPLWKEGKLSETLTDLDSLG 849

Query: 253 ISLLKHMLQVDPMKRAAIKDIREHEWF 279
           + L++  L+ DP +R + K + +H +F
Sbjct: 850 LDLIERTLKCDPAQRISCKKMLQHAYF 930
>01392
          Length = 1806

 Score = 89.0 bits (219), Expect = 4e-18,   Method: Compositional matrix adjust.
 Identities = 65/192 (33%), Positives = 93/192 (48%), Gaps = 32/192 (16%)
 Frame = -1

Query: 120  GRLDEKESRRLFQQILSGVDYCHRHMVVHRDLKPENVL---LDAHMNAKIADFGLSNMMS 176
            G L E+E+  + + I   +D+ H   + HRDLKPEN+L   LD  +  KI DF L++ +S
Sbjct: 1806 GHLCEREASLVVRHIARALDFLHSKGIAHRDLKPENILCEHLDDVVPVKICDFDLASGIS 1627

Query: 177  -DGEF-----LRTSCGSPNYAAPEVISG----RLYAGPEVDIWSSGVILYALLCGTLPF- 225
             DG+      L T  GS  Y APEV+              D+WS G+ILY +LCG  PF 
Sbjct: 1626 CDGDGTKTPELLTPVGSAEYMAPEVVDAWVGDSFSYDKRCDLWSLGIILYIMLCGYPPFY 1447

Query: 226  ----DD----------DHVPTLFKKICDGIFYTPQY----LNPSVISLLKHMLQVDPMKR 267
                +D          D    LF  I DG +  P      ++ S   L++H+L  +P KR
Sbjct: 1446 GQCGEDCGWNRGEACHDCQDMLFNSIQDGHYKFPSQEWTSISSSAKDLIRHLLVREPRKR 1267

Query: 268  AAIKDIREHEWF 279
             +  D+ +H W 
Sbjct: 1266 YSAADVLKHPWI 1231
>27546
          Length = 426

 Score = 88.6 bits (218), Expect = 7e-18,   Method: Compositional matrix adjust.
 Identities = 49/133 (36%), Positives = 76/133 (57%), Gaps = 3/133 (2%)
 Frame = -1

Query: 49  TGHKV--AVKILNRQKIRSLDVVGKIR-REIQNLKLFRHPHIIKLYQVISTPSDIFMVME 105
           +GH V  A KI+++ K   +D V K   RE++ L    HP+II+++ ++     IF+ M 
Sbjct: 414 SGHGVNLACKIIDKAKA-PIDFVKKFFPRELEILTRLDHPNIIQIHSILQRGPKIFIFMR 238

Query: 106 YVSGGELFDYICKNGRLDEKESRRLFQQILSGVDYCHRHMVVHRDLKPENVLLDAHMNAK 165
           Y   G++  +I K G +DE +++  F Q+   + Y H H + HRDLK EN+LL   +N K
Sbjct: 237 YAEKGDMLSHIKKTGPIDEAQTKVWFFQMAKALQYLHSHDIAHRDLKCENILLSKRLNVK 58

Query: 166 IADFGLSNMMSDG 178
           IADFG +    D 
Sbjct: 57  IADFGFARYCRDA 19
>21433
          Length = 590

 Score = 72.0 bits (175), Expect(2) = 9e-18,   Method: Compositional matrix adjust.
 Identities = 40/93 (43%), Positives = 57/93 (61%)
 Frame = +2

Query: 133 QILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYAA 192
           Q+ S ++YCH   V+HRD+KPEN+LL    + KIADFG S + +      T CG+ +Y  
Sbjct: 191 QLSSALEYCHYRKVIHRDIKPENLLLGLKGDLKIADFGWS-VHAPSSRRTTMCGTLDYLP 367

Query: 193 PEVISGRLYAGPEVDIWSSGVILYALLCGTLPF 225
           PE++ G+ +    VD+WS GV+ Y  L GT P 
Sbjct: 368 PEMVEGKTH-DENVDLWSLGVLCYEFLVGTPPL 463

 Score = 36.2 bits (82), Expect(2) = 9e-18,   Method: Compositional matrix adjust.
 Identities = 14/61 (22%), Positives = 35/61 (57%)
 Frame = +3

Query: 71  KIRREIQNLKLFRHPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRL 130
           ++RREI+     RH +I++++      + +++++E+   GEL+  + +  + DE E   +
Sbjct: 6   QLRREIEIQSHLRHDNILRMFGYFHDKTRVYLILEFAPKGELYKELQRCHKFDENEQHAI 185

Query: 131 F 131
           +
Sbjct: 186 Y 188
>03240
          Length = 1683

 Score = 87.0 bits (214), Expect = 2e-17,   Method: Compositional matrix adjust.
 Identities = 64/223 (28%), Positives = 98/223 (43%), Gaps = 46/223 (20%)
 Frame = -3

Query: 49   TGHKVAVKILNRQKIRSLDVVGKIRREIQNLKLFRHPHIIKLYQVISTPSDIFMVMEYVS 108
            TG   A+K L +  +   + V  ++ E   L    +  ++KLY      + ++ VM+YV 
Sbjct: 1219 TGMLYAMKTLRKSDVLKRNQVAHVKAERDILAEADNEWVVKLYYSFQDHNYLYFVMDYVP 1040

Query: 109  GGELFDYICKNGRLDEKESRRLFQQILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKIAD 168
            GG+L   + +   LDE  +R    +++  ++  HR   +HRD+KP+N+L+D + + K+ D
Sbjct: 1039 GGDLMGLLIRMEILDEPLARFYVAELVQAIESVHRMGFIHRDIKPDNILIDRNGHIKLTD 860

Query: 169  FGLSN----------MMSDGEFLR-----TSC---------------------------- 185
            FGL               DG   R       C                            
Sbjct: 859  FGLCTGFRWTHNSKYYQRDGTHARQDSMEVKCQLDEQCQCEILKPLERRRKREQRCLAHS 680

Query: 186  --GSPNYAAPEVISGRLYAGPEV-DIWSSGVILYALLCGTLPF 225
              G+PNY APEV+S RL     V D WS GVIL+ +L G  PF
Sbjct: 679  LVGTPNYIAPEVLS-RLGGYTSVCDWWSVGVILFEMLVGHPPF 554
>31885
          Length = 529

 Score = 85.5 bits (210), Expect = 5e-17,   Method: Compositional matrix adjust.
 Identities = 48/146 (32%), Positives = 75/146 (51%), Gaps = 4/146 (2%)
 Frame = -2

Query: 84  HPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVDYCHR 143
           HP ++ L+       D+FMV++   GG+L  ++ +     E   +    Q+   +DY   
Sbjct: 495 HPFLVNLWYAFQDEEDLFMVVDLFLGGDLRYHMQQEVSFREDCVKFYLCQLALVLDYLRS 316

Query: 144 HMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEV----ISGR 199
             +VHRD+KP+N+LLD   +  + DF ++  + D E   ++ G+  Y APEV    I+ R
Sbjct: 315 QKIVHRDIKPDNILLDEQGHCHVTDFNIATQLEDDELATSTSGTRPYMAPEVYGVAINER 136

Query: 200 LYAGPEVDIWSSGVILYALLCGTLPF 225
              G  VD WS GV L+ LL    PF
Sbjct: 135 RGYGFPVDWWSLGVSLFELLKKRRPF 58
>14126
          Length = 1265

 Score = 84.3 bits (207), Expect = 1e-16,   Method: Compositional matrix adjust.
 Identities = 62/196 (31%), Positives = 99/196 (50%), Gaps = 7/196 (3%)
 Frame = +3

Query: 76  IQNLKLFRHPHIIKLYQVI-STPSD----IFMVMEYVSGGELFDYI--CKNGRLDEKESR 128
           ++ L+ + HP++++L  V  +T +D    + +V EY+   +L  Y+  C +  L     +
Sbjct: 351 LKQLEQYEHPNVVRLLDVSHNTITDREIRLNLVFEYIEH-DLATYLAKCPSPGLGPDRIK 527

Query: 129 RLFQQILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSP 188
            L  Q+L+GVD+ H + +VHRDLKP+N+L+      K+ADFGL+ + S    L T   + 
Sbjct: 528 DLMLQLLNGVDFLHSNRIVHRDLKPQNLLISKDGRLKLADFGLARIYSFHMALTTVVVTL 707

Query: 189 NYAAPEVISGRLYAGPEVDIWSSGVILYALLCGTLPFDDDHVPTLFKKICDGIFYTPQYL 248
            Y +PEV+    Y G  VDIWS G I   L      F         KKI + I   P   
Sbjct: 708 WYRSPEVLMQAEY-GTSVDIWSCGCIFAELFTRRALFKGSSEFDQLKKIFEVIGLPPAGD 884

Query: 249 NPSVISLLKHMLQVDP 264
            P  +S+ ++  +  P
Sbjct: 885 WPEGVSVHRNSFRPTP 932
>18921
          Length = 697

 Score = 83.6 bits (205), Expect = 2e-16,   Method: Compositional matrix adjust.
 Identities = 55/176 (31%), Positives = 91/176 (51%), Gaps = 2/176 (1%)
 Frame = +2

Query: 51  HKVAVKILNRQKIRSLDVVGKIRREIQNLKLFRHPHIIKLYQVISTPSDIFMVMEYVSGG 110
           HK   ++L  +++     + +I +EI  ++     +I+K Y      +D+++VMEY   G
Sbjct: 92  HKETGQVLAIKQVPVDTDLQEIIKEISIMQQCDSKYIVKYYGSYFKNTDLWIVMEYCGAG 271

Query: 111 ELFDYI-CKNGRLDEKESRRLFQQILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKIADF 169
            + D +  +N  L E+E   +    L G+ Y H    +HRD+K  N+LL+   +AK+ADF
Sbjct: 272 SVSDIMRLRNKTLVEREIATILYYTLKGLXYLHSRRKIHRDIKAGNILLNNEGHAKLADF 451

Query: 170 GLSNMMSDGEFLR-TSCGSPNYAAPEVISGRLYAGPEVDIWSSGVILYALLCGTLP 224
           G++  ++D    R T  G+P + APEVI    Y     DIWS G+    +  G  P
Sbjct: 452 GVAGQLTDTMAKRNTVIGTPYWMAPEVIQEIGYDCV-ADIWSLGITALEMAEGKPP 616
>29581
          Length = 1278

 Score = 83.2 bits (204), Expect = 3e-16,   Method: Compositional matrix adjust.
 Identities = 72/249 (28%), Positives = 111/249 (44%), Gaps = 36/249 (14%)
 Frame = -2

Query: 82   FRHPHIIKLYQVISTPS--DIFMVMEYVSG--GELFDYICKNGRLDEKESRRLFQQILSG 137
             RH +I++L +V+   S   +F+VMEY       L D +       E + + +  Q+L G
Sbjct: 1184 LRHQNIVQLQEVVVGKSLDSLFLVMEYCEQDLASLLDNM--PAPFSESQVKCIVLQLLKG 1011

Query: 138  VDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLS-NMMSDGEFLRTSCGSPNYAAPEVI 196
            + Y H   ++HRDLK  N+L+      KIADFGL+ N     + +     +  Y APE++
Sbjct: 1010 LRYLHEAFIIHRDLKVSNLLMTDKGCVKIADFGLARNYGKPQKPMTPKVVTLWYRAPELL 831

Query: 197  SGRLYAGPEVDIWSSGVILYALLCGTLPF--------------------DDDHVP----- 231
             G       +D+WS+G IL  LL G  P                     +D   P     
Sbjct: 830  FGSKTHSTAIDMWSAGCILGELL-GHKPLMPGRSDLQQIELIMELLGTPNDTIWPGFSQL 654

Query: 232  ------TLFKKICDGIFYTPQYLNPSVISLLKHMLQVDPMKRAAIKDIREHEWFKQDLPK 285
                  TL K+  + + +T  +L+ S I LL  +    P KRA  +D  EH +FK+    
Sbjct: 653  PAFEQFTLKKQPYNNLRHTFPWLSESGIRLLNGLFMYHPQKRATAEDCLEHSYFKEQ--- 483

Query: 286  YLFPEDPSY 294
              +P DP +
Sbjct: 482  -PYPCDPEF 459
>00300
          Length = 2318

 Score = 81.3 bits (199), Expect = 9e-16,   Method: Compositional matrix adjust.
 Identities = 72/245 (29%), Positives = 119/245 (48%), Gaps = 13/245 (5%)
 Frame = -1

Query: 49   TGHKVAVKILNRQKIRSLDVVGKIRREIQNLKLFRHPHIIKLYQVISTPSDIFMVMEYVS 108
            TG  +A+K +  Q    L  + ++  EI+  +  +H +++K Y V     ++ M MEY  
Sbjct: 1586 TGELMALKEMKFQP-NDLQQLREMCDEIKIFEGIQHENLVKYYGVEVHKDEMLMFMEYCD 1410

Query: 109  GGELFDYICKNGRLDEKESRRLFQQILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKIAD 168
             G + +   K G L E   RR  ++I+  V++ H + +VHRD+K  N+ L ++ + K+ D
Sbjct: 1409 TGTI-EEAAKMG-LPEYLIRRYTREIVLAVNHLHENSIVHRDIKGANIFLTSNGHVKLGD 1236

Query: 169  FGLSNMMSD-----GEFLRTSCGSPNYAAPEVISGRLYA--GPEVDIWSSGVILYALLCG 221
            FG S  +       GEF     G+  Y APEV +       G   DIWS G ++  +  G
Sbjct: 1235 FGCSVKLKSHTTMPGEF-HNLVGTTAYMAPEVFTQNDQGGYGRAADIWSLGCVVIEMATG 1059

Query: 222  TLPFDD-DHVPTLFKKICDGIFYTPQYLNPSVISLL-KHMLQV----DPMKRAAIKDIRE 275
              P+ D D+   +  K+  GI + P    P  +S+  KH L +    DP +RA    + +
Sbjct: 1058 KRPWHDLDNNYQIMYKV--GIGHKPAV--PDSLSVEGKHFLDLIMCHDPAQRALASQLLD 891

Query: 276  HEWFK 280
            H + K
Sbjct: 890  HTFTK 876
>01718
          Length = 959

 Score = 79.3 bits (194), Expect = 3e-15,   Method: Compositional matrix adjust.
 Identities = 72/250 (28%), Positives = 117/250 (46%), Gaps = 14/250 (5%)
 Frame = +3

Query: 46  HELTGHKVAVKILNRQKIRSLDVVGKIRREIQNLKLFRHPHIIKLYQVISTPSDIFMVME 105
           H +TG  +A+K+      R       + RE+Q L   +H +I++   V      +  + E
Sbjct: 210 HRITGQVMALKMNTMTSNRH-----NMLREVQLLNRLQHANILRFMGVCVHEGQLHALTE 374

Query: 106 YVSGGELFDYI-CKNGRLDEKESRRLFQQILSGVDYCHRHMVVHRDLKPENVLL---DAH 161
           Y+  G L   +  K+  L   +  +L   +  G+DY H    +HRDL  +N+L+   D H
Sbjct: 375 YIPSGNLEQLLEKKDEELPWTQRIQLTLGLARGLDYLHSTRFIHRDLTSKNILIRREDNH 554

Query: 162 -MNAKIADFGLSNMMS---DGEFLRTSCGSPNYAAPEVISGRLYAGPEVDIWSSGVILYA 217
             +A IADFGL+  +    D E L T  GSP + APEV++G  Y     D++S G+I+  
Sbjct: 555 GYHAVIADFGLATKIPDPLDKEKLPT-VGSPYWMAPEVLNGHFY-NERADLFSVGIIMCE 728

Query: 218 LLCGTLPFDDDHVPTL------FKKICDGIFYTPQYLNPSVISLLKHMLQVDPMKRAAIK 271
            +   +P D D +P +      +  + + I Y P       + L     QVDP KR   +
Sbjct: 729 -ITARIPADPDIMPRMNNFGVDYVALSEMISYCPL----DYLQLAFKCCQVDPQKRP--R 887

Query: 272 DIREHEWFKQ 281
            +   EW ++
Sbjct: 888 GVEIIEWLEK 917
>01966
          Length = 1735

 Score = 79.0 bits (193), Expect = 4e-15,   Method: Compositional matrix adjust.
 Identities = 61/193 (31%), Positives = 97/193 (50%), Gaps = 5/193 (2%)
 Frame = -1

Query: 46   HELTGHKVAVKILNRQKIRSLDVVGKIRREIQNLKLFRHPHIIKLYQVISTPSDIFMVME 105
            H  TG K+A+K + R +     V     REI  L+  RH +I+ L  VI     +F+V E
Sbjct: 1648 HRATGRKLAMKKI-RLRGSEDGVPSSAIREIAMLRELRHTNIVCLEDVIMEDERLFLVFE 1472

Query: 106  YVSGGELFDYICK---NGRLDEKESRRLFQQILSGVDYCHRHMVVHRDLKPENVLLDAHM 162
            ++S  +L  YI K      LD +  +    QI++G+++CH+  +VHRDLKP+N+L++   
Sbjct: 1471 FLSM-DLKMYIDKFPEGVVLDRRLVKSYVFQIVTGINFCHQRRIVHRDLKPQNLLINHTG 1295

Query: 163  NAKIADFGLSNMMSDGEFLRT-SCGSPNYAAPEVISGRLYAGPEVDIWSSGVIL-YALLC 220
              KIADFG++   +      T    +  Y APE++ G     P    W+ G +   + +C
Sbjct: 1294 AIKIADFGMARTFALPVRAYTHEVVTLWYRAPEILMGPQSTPPX---WTCGALEPSSPIC 1124

Query: 221  GTLPFDDDHVPTL 233
             + P      P L
Sbjct: 1123 SSGPLSSRATPKL 1085
>06405
          Length = 1965

 Score = 78.6 bits (192), Expect = 7e-15,   Method: Compositional matrix adjust.
 Identities = 61/228 (26%), Positives = 103/228 (45%), Gaps = 7/228 (3%)
 Frame = +1

Query: 53  VAVKILNRQKIRSLDVVGKIRREIQNLKLFRHPHIIKLYQVISTPSDIFMVMEYVSGGEL 112
           VAVK L    +   D +     E   +K  +HP++++L  V +     ++V E++  G L
Sbjct: 343 VAVKTLKEDTMALNDFL----EEAAIMKEMKHPNLVQLLGVCTREPPFYIVTEFMPHGNL 510

Query: 113 FDYICKNGRLDEKESRRLF--QQILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFG 170
            DY+  + R +   +  ++   QI SG+ Y      +HRDL   N L+      K+ADFG
Sbjct: 511 LDYLRSSTREENGPTALMYMATQIASGMAYLETKNFIHRDLAARNCLVADSNMVKVADFG 690

Query: 171 LSNMMSDGEFLRTSCGSP---NYAAPEVISGRLYAGPEVDIWSSGVILYALLC-GTLPFD 226
           L+ +M D  +     G+     + APE ++   ++    DIW+ GV+L+ L   G  P+ 
Sbjct: 691 LARLMKDDTYT-AHIGAKFPIKWTAPEGLAFNRFST-RSDIWAFGVLLWELATYGMSPYP 864

Query: 227 DDHVPTLFKKICDGI-FYTPQYLNPSVISLLKHMLQVDPMKRAAIKDI 273
              +  ++  +  G     P      V  L+    Q DP  R   K+I
Sbjct: 865 GVELTEVYHLLERGYRMERPPGTPADVYILMLKCWQWDPKDRPTFKEI 1008
>21808
          Length = 1011

 Score = 77.8 bits (190), Expect = 1e-14,   Method: Compositional matrix adjust.
 Identities = 52/177 (29%), Positives = 89/177 (50%), Gaps = 4/177 (2%)
 Frame = +1

Query: 53  VAVKILNRQKIRSLDVVGKIRREIQNLKLFRHPHIIKLYQVISTPSDIFMVMEYVSGGEL 112
           VA+K L    +   D +     E Q +K  RHP +I+LY V +    IF++ E +  G L
Sbjct: 28  VAIKTLKSGTMDPKDFLA----EAQIMKKLRHPKLIQLYAVCTQDDPIFIITELMKNGSL 195

Query: 113 FDYICKNGRLDEKESR-RLFQQILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGL 171
            +++   GR+ +  +   +  QI  G+ Y      +HRDL   N+L+  +   KIADFGL
Sbjct: 196 LEFLQGKGRVLKLPALIDIGAQIACGMAYLESQNYIHRDLAARNILVSDNNTVKIADFGL 375

Query: 172 SNMMSDGEF-LRTSCGSP-NYAAPEVISGRLYAGPEVDIWSSGVILYALLC-GTLPF 225
           + ++ + E+  R     P  + APE  +   +   + D+WS G++L   +  G +P+
Sbjct: 376 ARVIKEDEYEARVGARFPIKWTAPEAANYNRFT-IKSDVWSFGILLTETVTYGRVPY 543
>27405
          Length = 532

 Score = 74.3 bits (181), Expect = 1e-13,   Method: Compositional matrix adjust.
 Identities = 46/152 (30%), Positives = 81/152 (53%), Gaps = 4/152 (2%)
 Frame = -3

Query: 49  TGHKVAVKILNRQKIRSLDVVGKIRREIQNLKLFR----HPHIIKLYQVISTPSDIFMVM 104
           TG   A+K L++++I+          E   L L       P I+ +     TP  +  ++
Sbjct: 494 TGKMYAMKCLDKKRIKMKGGETLALNERIMLSLVSTGEGSPFIVCMTYAFQTPEKLCFIL 315

Query: 105 EYVSGGELFDYICKNGRLDEKESRRLFQQILSGVDYCHRHMVVHRDLKPENVLLDAHMNA 164
           + ++GG+L  ++ ++G   EKE R    +++ G+++ H   VV+RDLKP N+LLD + + 
Sbjct: 314 DLMNGGDLHYHLSQHGVFTEKEVRFYAAEVMLGLEHMHSRFVVYRDLKPANILLDENGHV 135

Query: 165 KIADFGLSNMMSDGEFLRTSCGSPNYAAPEVI 196
           +I+D GL+   S  +    S G+  Y APEV+
Sbjct: 134 RISDLGLACDFSKKK-PHASVGTHGYMAPEVL 42
>04591
          Length = 1117

 Score = 74.3 bits (181), Expect = 1e-13,   Method: Compositional matrix adjust.
 Identities = 66/254 (25%), Positives = 109/254 (42%), Gaps = 45/254 (17%)
 Frame = -2

Query: 74   REIQNLKLFRHPHIIKLYQVIST--------PSDIFMVMEYVS---GGELFDYICKNGRL 122
            REI+ L+   H ++++L ++  T         S  +++ EY      G L +   K    
Sbjct: 1074 REIKILQQLEHENVVQLQEICHTQAGPYNRYKSTFYLIFEYCDYDLAGLLNNLRVKFSLA 895

Query: 123  DEKESRRLFQQILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLR 182
            D+K    L  Q+L+G+ Y H   ++HRD+K  N+LL      K+ADFGLS      + L 
Sbjct: 894  DKKN---LMSQLLNGLFYIHTKQILHRDIKAANILLTRDGVLKLADFGLSRPWVKSKRLT 724

Query: 183  TSCGSPNYAAPEVISGRLYAGPEVDIWSSGVILYAL---------------------LCG 221
                +  Y  PE++ G    GPE+D+W  G I+  +                     LCG
Sbjct: 723  NRVVTLWYRPPELLLGEREYGPEIDMWGVGCIMAEMWSRKPLMQGRSEQHQLSLITDLCG 544

Query: 222  TLPFDDDHVPTLFKKICDGIFYTPQ----YLNPSVISLLKH---------MLQVDPMKRA 268
            +L  + +  P + K    G    PQ     +   ++ LLK+          L++DP +R 
Sbjct: 543  SL--NAEVWPGVTKLELYGKLDLPQGKPRKVKERMLDLLKNKEGAELIDIFLRLDPGQRM 370

Query: 269  AIKDIREHEWFKQD 282
               +   H++F  D
Sbjct: 369  NCDNALSHDFFWVD 328
>26560
          Length = 398

 Score = 70.5 bits (171), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 41/115 (35%), Positives = 63/115 (54%)
 Frame = -1

Query: 111 ELFDYICKNGRLDEKESRRLFQQILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFG 170
           +L  ++ ++G   EKE R    +++ G+++ H   VV+RDLKP N+LLD + + +I+D G
Sbjct: 398 DLHYHLSQHGVFTEKEVRFYAAEVMLGLEHMHSRFVVYRDLKPANILLDENGHVRISDLG 219

Query: 171 LSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAGPEVDIWSSGVILYALLCGTLPF 225
           L+   S       S G+  Y APEV+          D +S G +LY LL G  PF
Sbjct: 218 LACDFSKKR-PHASVGTHGYMAPEVLMKGQSYDSSADWFSFGCMLYKLLKGHSPF 57
>00392
          Length = 668

 Score = 67.4 bits (163), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 44/199 (22%), Positives = 100/199 (50%), Gaps = 9/199 (4%)
 Frame = +3

Query: 71  KIRREIQNLKLFRHPHIIKLYQVISTPSD-----IFMVMEYVSGGELFDYICKNGRLDEK 125
           + + E + LK  +HP+I++ +      +      I +V E ++ G L  Y+ +  + + K
Sbjct: 69  RFKEEAEMLKELQHPNIVRFFDYWEEHNHRNRKVIILVTELMTSGTLKTYLKRFKKPNVK 248

Query: 126 ESRRLFQQILSGVDYCHRHM--VVHRDLKPENVLLDAHMNA-KIADFGLSNMMSDGEFLR 182
             +   +Q+L G+ + H     V+HRDLK +N+ +     + KI D GL+  + +  F +
Sbjct: 249 ILKNWCRQVLKGLYFLHTRTPPVIHRDLKCDNIFITGPTGSVKIGDLGLAT-LKNQSFAK 425

Query: 183 TSCGSPNYAAPEVISGRLYAGPEVDIWSSGVILYALLCGTLPFDD-DHVPTLFKKICDGI 241
           +  G+P + APE+     +    VD+++ G+ +  +     P+ +  +   ++K++  G+
Sbjct: 426 SVIGTPEFMAPEMYEE--HYDEAVDVYAFGMCMLEMASSEYPYSECSNAAQIYKRVTSGV 599

Query: 242 FYTPQYLNPSVISLLKHML 260
              P+ L+   I+ ++ ++
Sbjct: 600 L--PEALDKVAITEIRDII 650
>19301
          Length = 712

 Score = 67.0 bits (162), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 41/126 (32%), Positives = 65/126 (51%)
 Frame = +2

Query: 47  ELTGHKVAVKILNRQKIRSLDVVGKIRREIQNLKLFRHPHIIKLYQVISTPSDIFMVMEY 106
           +L   +VAVK     K+R +        +I+NL+   HP+II    V +      ++MEY
Sbjct: 365 KLCAEEVAVK-----KVRDIK-----ETDIRNLRKLNHPNIISFKGVCTQAPCYCIIMEY 514

Query: 107 VSGGELFDYICKNGRLDEKESRRLFQQILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKI 166
              G+L++ +     +         +QI SG++Y H H ++HRDLK  NVL+  +   KI
Sbjct: 515 CPYGQLYEVLRDGKEIPPALVLDWSKQIASGMNYLHSHKIIHRDLKSPNVLVAKNDVVKI 694

Query: 167 ADFGLS 172
           +DFG S
Sbjct: 695 SDFGTS 712
>18663
          Length = 600

 Score = 63.9 bits (154), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 41/113 (36%), Positives = 56/113 (49%), Gaps = 15/113 (13%)
 Frame = +2

Query: 183 TSCGSPNYAAPEVISGRLYAGPEVDIWSSGVILYALLCGTLPF---------DDDHVPTL 233
           T CG+PNY APE++ G  Y G  VD W+ GV+LY +L G  PF         D +    L
Sbjct: 5   TFCGTPNYIAPEILRGEDY-GFSVDWWALGVLLYEMLAGRSPFDIAGASENPDQNTEDYL 181

Query: 234 FKKICDGIFYTPQYLNPSVISLLKHMLQVDPMKR------AAIKDIREHEWFK 280
           F+ I +     P+ L+    S+LK  L  +P  R      +A  DI  H +FK
Sbjct: 182 FQVILEKTIRIPRSLSVKAASVLKGFLNKNPADRLGCHRESAFMDIVNHPFFK 340
>19094
          Length = 898

 Score = 63.9 bits (154), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 39/110 (35%), Positives = 58/110 (52%), Gaps = 1/110 (0%)
 Frame = +1

Query: 118 KNGRLDEKESRRLFQQILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSD 177
           +N  L E+E   +    L G+ Y H    +HRD+K  N+LL+   +AK+ADFG++  ++D
Sbjct: 37  RNKTLVEREIATILYYTLKGL*YLHSRRKIHRDIKAGNILLNNEGHAKLADFGVAGQLTD 216

Query: 178 GEFLR-TSCGSPNYAAPEVISGRLYAGPEVDIWSSGVILYALLCGTLPFD 226
               R T  G+P + APEVI    Y     DIWS G+    +  G L  +
Sbjct: 217 TMAKRNTVIGTPYWMAPEVIQEIGYD-CVADIWSLGITALEMAEGNLHME 363
>20152
          Length = 445

 Score = 63.5 bits (153), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 31/88 (35%), Positives = 47/88 (53%)
 Frame = +1

Query: 193 PEVISGRLYAGPEVDIWSSGVILYALLCGTLPFDDDHVPTLFKKICDGIFYTPQYLNPSV 252
           PE++ G  Y  P VD+WS GVILY L+ G  PF + +       I D  +  P +++   
Sbjct: 1   PEILLGDSYDAPAVDVWSLGVILYMLVVGEAPFQEANDSETLTMIMDCRYQIPPHISHKC 180

Query: 253 ISLLKHMLQVDPMKRAAIKDIREHEWFK 280
             L++ MLQ +P+ RA++  I  H W  
Sbjct: 181 QDLIEKMLQREPVDRASLPHILAHPWLN 264
>01756
          Length = 1858

 Score = 63.2 bits (152), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 52/196 (26%), Positives = 92/196 (46%), Gaps = 23/196 (11%)
 Frame = -3

Query: 74   REIQNLKLFRHPHIIKLYQVISTP--------SDIFMVMEYVS---GGELFDYICKNGRL 122
            REI+ L+L  H +++ L ++ ST         S  ++V E+      G L +    +   
Sbjct: 1598 REIKILQLLNHENVVDLIEICSTKATSANRYKSMFYLVFEFCEHDLAGLLSNM---SVVF 1428

Query: 123  DEKESRRLFQQILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLR 182
            +  E + + +Q+++G+ Y HR+ ++HRD+K  N+L+      K+ADFGL+   S    LR
Sbjct: 1427 NLPEIKEVMKQLMNGLYYIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVN--LR 1254

Query: 183  TSCGSPN------YAAPEVISGRLYAGPEVDIWSSGVILYAL------LCGTLPFDDDHV 230
                  N      Y  PE++ G       +D W +G I+  +      + GT    + + 
Sbjct: 1253 QPNRYTNRVVTLWYRPPELLLGDRNYSTAIDQWGAGCIMAEMWTRNPIMQGT---TEQNQ 1083

Query: 231  PTLFKKICDGIFYTPQ 246
             TL  ++C  I  TP+
Sbjct: 1082 LTLITQLCGSI--TPE 1041
>26711
          Length = 405

 Score = 62.8 bits (151), Expect = 4e-10,   Method: Composition-based stats.
 Identities = 41/125 (32%), Positives = 62/125 (49%), Gaps = 5/125 (4%)
 Frame = -2

Query: 132 QQILSGVDYCHRHMVVHRDLKPENVLL--DAHMNAKIADFGLSNMMSDGEFLRTSCGSPN 189
           +Q+L  + + H   VVH DLKP N+LL  D   + ++ DFGL+  +   +    + G+P 
Sbjct: 395 KQVLDILQHVHAQGVVHMDLKPSNLLLSGDKLDSVQLIDFGLARKLYPPQETFLNHGTPG 216

Query: 190 YAAPEVISGRLYAGPEVDIWSSGVILYALLCGTLPFDDDHVPTLFKK--ICDGIF-YTPQ 246
           + +PE +  +  +    D+W  GV+ Y LL G  PF  D      KK   CD  F   P 
Sbjct: 215 FTSPEALDVKPISTAS-DVWGVGVLAYILLSGQSPFQADSATESLKKTQTCDWSFDVCPS 39

Query: 247 YLNPS 251
           + N S
Sbjct: 38  FSNMS 24
>13212
          Length = 1067

 Score = 62.4 bits (150), Expect = 4e-10,   Method: Compositional matrix adjust.
 Identities = 53/166 (31%), Positives = 70/166 (42%), Gaps = 26/166 (15%)
 Frame = -1

Query: 133 QILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLR-TSCGSPNYA 191
           ++   +D+ HRH V+HRD+K  NVLL      K+ADFG+S   +  +  R T  G+P + 
Sbjct: 956 EMCMALDFLHRHHVIHRDIKAGNVLLTIDGEVKLADFGVSAKNTQTQQKRDTFIGTPYWM 777

Query: 192 APEVI-SGRLYAGP---EVDIWSSGVILYALLCGTLPFDDDH------------VPT--- 232
           APEV+    L   P   + DIWS GV L        P  + H             PT   
Sbjct: 776 APEVVLCETLKDTPYDFKADIWSLGVTLIEFAQIEPPNKEMHPMRVLIKIHKSDPPTLEK 597

Query: 233 ------LFKKICDGIFYTPQYLNPSVISLLKHMLQVDPMKRAAIKD 272
                 LFK            L P+   LL+H      MKRA   D
Sbjct: 596 PKKWTKLFKDFIAKCLVKDPNLRPTAAELLEHPF----MKRATATD 471
>11780
          Length = 1713

 Score = 62.4 bits (150), Expect = 5e-10,   Method: Compositional matrix adjust.
 Identities = 38/126 (30%), Positives = 66/126 (52%), Gaps = 3/126 (2%)
 Frame = +3

Query: 74  REIQNLKLFRHPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGR--LDEKESRRLF 131
           +E   +   RH ++++L  V+   + IF+V E++  G L +Y+   GR  + +K+     
Sbjct: 726 QEASVMTSLRHDNLVRLIGVVLGET-IFLVTEFMGKGNLVEYLRSRGRSVITKKDQINFA 902

Query: 132 QQILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSP-NY 190
               + ++Y     +VHRDL   NVL+     AK++DFGL+     G+F +TS   P  +
Sbjct: 903 TDTCAAMEYLESKRLVHRDLAARNVLVHDDGKAKVSDFGLAKF---GDFSQTSVKFPIKW 1073

Query: 191 AAPEVI 196
            APE +
Sbjct: 1074TAPEAL 1091
>09007
          Length = 1440

 Score = 62.0 bits (149), Expect = 7e-10,   Method: Compositional matrix adjust.
 Identities = 47/178 (26%), Positives = 86/178 (48%), Gaps = 10/178 (5%)
 Frame = -1

Query: 52  KVAVKILNRQKIRSLDVVGKIRREIQNLKLFRHPHIIKLYQVI-STPSDIFMVMEYVSGG 110
           +VAVK L++ KI       +  +E   +++  H +I+++Y V+    +DI +V E     
Sbjct: 789 QVAVKCLSKDKIHKDG--QEFLKETAIMQMLDHENIVRVYGVVMDNGADIMLVTELAPMR 616

Query: 111 ELFDYICK-NGRLDEKESR--RLFQQILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKIA 167
            L + + + + R+D    R     QQ+  G+ Y     +VHRDL   N+LL +    KI+
Sbjct: 615 SLLECVKEVSARVDFSVPRLCDFSQQVCDGMSYLESKRLVHRDLAARNILLFSKSKVKIS 436

Query: 168 DFGLSNMMSDG-EFLRTS-----CGSPNYAAPEVISGRLYAGPEVDIWSSGVILYALL 219
           D G+S  +  G E+ ++        +  + APE      ++    D+W+ GV+L+   
Sbjct: 435 DVGVSGALGAGKEYYQSQQTIHLQNAVAWCAPESFRNLCFSSAS-DVWAFGVLLWEFF 265
>11185
          Length = 473

 Score = 60.5 bits (145), Expect = 2e-09,   Method: Composition-based stats.
 Identities = 48/172 (27%), Positives = 76/172 (44%), Gaps = 25/172 (14%)
 Frame = +1

Query: 133 QILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLS-------------------- 172
            +++G+ Y H   ++  DL+P  VLLD     K ADFGLS                    
Sbjct: 25  HLVTGLHYIHSLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEAGDQ 204

Query: 173 -NMMSDGEFLRT--SCGSPNYAAPEVISGRLYAGPEV--DIWSSGVILYALLCGTLPFDD 227
            N+ S  E ++   + GSP Y APEV  G   A P +  D+W+ G + Y +  G+     
Sbjct: 205 WNIQSAEEMMKQVPTSGSPTYMAPEVFQG---AEPSIMSDLWALGCVFYEMFSGS----- 360

Query: 228 DHVPTLFKKICDGIFYTPQYLNPSVISLLKHMLQVDPMKRAAIKDIREHEWF 279
                L  K       +P++LN     LL+ +LQ D  +R +   + +H ++
Sbjct: 361 ----RLSAKP------SPEFLN-----LLESLLQKDSTRRLSWASLVKHAFW 471
>00486
          Length = 797

 Score = 60.1 bits (144), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 33/104 (31%), Positives = 53/104 (50%), Gaps = 5/104 (4%)
 Frame = -2

Query: 183 TSCGSPNYAAPEVISGRLYAGPEVDIWSSGVILYALLCGTLPFDDDHVPTLFKKICDGIF 242
           T CG+  Y APE+++ R   G  VD WS G ++Y +L G+ PF  ++      KI  G  
Sbjct: 781 TFCGTIEYMAPEILT-RTGHGKAVDWWSLGALMYDMLTGSPPFTAENRKKTIDKILKGKL 605

Query: 243 YTPQYLNPSVISLLKHMLQVDPMKRAA-----IKDIREHEWFKQ 281
             P YL      L+K +L+ +P +R          I++H++F+ 
Sbjct: 604 NLPPYLTNEARGLIKKLLRKNPAERLGGGHDDSGPIKDHQFFRN 473
>04852
          Length = 1462

 Score = 59.3 bits (142), Expect = 4e-09,   Method: Compositional matrix adjust.
 Identities = 53/225 (23%), Positives = 94/225 (41%), Gaps = 31/225 (13%)
 Frame = +1

Query: 53  VAVKILNR--QKIRSLDVVGKIRREIQNLKLFRHPHIIKLYQVISTPSDIFMVMEYVSGG 110
           VAVK+L      +   D V +++      K+  H +I+      +    +++++E+   G
Sbjct: 28  VAVKMLRDIVTAVEEQDFVQELQVMKAVKKMGSHINIVNFLGCCTQGGPLWVIVEFAKNG 207

Query: 111 ELFDYI--CKNG-----------------------RLDEKESRRLFQQILSGVDYCHRHM 145
            L D++  C++G                        +  K       QI  G+++     
Sbjct: 208 NLRDFLESCRDGINGYGKFVSPQDPGWYTKTPGGHVIRRKNLLSYAFQIARGMEFLASRK 387

Query: 146 VVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGS---PNYAAPEVISGRLYA 202
            +HRDL   NVL+      KIADFGLS     G++ +   G      + APE +    Y 
Sbjct: 388 CIHRDLAARNVLVTEEHVLKIADFGLSRT---GDYYKKRSGGRLPVKWMAPEALFDMRYT 558

Query: 203 GPEVDIWSSGVILYALLC-GTLPFDDDHVPTLFKKICDGIFYTPQ 246
             + D+WS GV+L+ +   G +P+       L+ K+ D  +  P+
Sbjct: 559 -TKSDVWSFGVVLWEIFSLGGMPYASIPNEELYSKLLDDAYRMPR 690
>14116
          Length = 1017

 Score = 59.3 bits (142), Expect = 4e-09,   Method: Compositional matrix adjust.
 Identities = 46/172 (26%), Positives = 80/172 (46%), Gaps = 5/172 (2%)
 Frame = -1

Query: 53  VAVKILNRQKIRSLDVVGKIRREIQNLKLFRHPHIIKLYQVISTPSDI-FMVMEYVSGGE 111
           VAVK L+    R +++     +E   +K F H +++ L  +     D+  +V+ ++  G+
Sbjct: 540 VAVKTLHNNNPREIEL-QSFLQEALIMKDFHHSNVLTLIGICLNLDDMPLVVLPFMKHGD 364

Query: 112 LFDYICKNGRLDEKESRRLFQ-QILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFG 170
           L  YI  +      +   ++   I  G+DY      VHRDL   N +LD   + K+ADFG
Sbjct: 363 LLTYIRDDQHQPTIKDLIMYGVDIARGMDYLAGLKFVHRDLAARNCMLDEDFHVKVADFG 184

Query: 171 LSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAG---PEVDIWSSGVILYALL 219
           L+  + + E+  +           +    L  G    + D+WS GV+L+ LL
Sbjct: 183 LARDIYEKEYYSSENKKAKLPVKWMALESLEKGNYDSKTDVWSYGVVLWELL 28
>12786
          Length = 460

 Score = 58.9 bits (141), Expect = 5e-09,   Method: Compositional matrix adjust.
 Identities = 39/126 (30%), Positives = 59/126 (46%), Gaps = 22/126 (17%)
 Frame = -3

Query: 122 LDEKESRRLFQQILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGE-- 179
           LD    +  ++++L  V   H   V+H DLKP N +L A  N K+ DFG++N +   +  
Sbjct: 419 LDRMMIKFYWREMLRAVKALHNEGVIHSDLKPANFMLVAG-NLKLIDFGIANTLQQDKTS 243

Query: 180 FLRTS-CGSPNYAAPEVISG-------------------RLYAGPEVDIWSSGVILYALL 219
            L+ S  G+P+Y +PE I                     +   G   D+WS G ILY ++
Sbjct: 242 VLKDSRVGTPSYMSPEAIMAACDDSADDSMEEDGHRTKPKYKVGVRSDVWSLGCILYNMV 63

Query: 220 CGTLPF 225
            G  PF
Sbjct: 62  YGRTPF 45
>19761
          Length = 473

 Score = 57.4 bits (137), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 28/89 (31%), Positives = 51/89 (57%), Gaps = 3/89 (3%)
 Frame = -3

Query: 131 FQQILSGVDYCHRH--MVVHRDLKPENVLLDAHMNAKIADFGLSNMMSD-GEFLRTSCGS 187
             Q  S ++Y H H  +++HRDLKP+N+ +    + ++ D GL+  ++   +F  +  G+
Sbjct: 405 LMQTASALNYMHTHTPVILHRDLKPQNIYVTEKGDVRLGDLGLARKLTGPADFATSQVGT 226

Query: 188 PNYAAPEVISGRLYAGPEVDIWSSGVILY 216
             Y +PE++S + Y   + DIWS G + Y
Sbjct: 225 IMYLSPEILSQQPY-NSKSDIWSLGCVFY 142
>14477
          Length = 493

 Score = 57.4 bits (137), Expect = 1e-08,   Method: Composition-based stats.
 Identities = 38/124 (30%), Positives = 63/124 (50%)
 Frame = -1

Query: 53  VAVKILNRQKIRSLDVVGKIRREIQNLKLFRHPHIIKLYQVISTPSDIFMVMEYVSGGEL 112
           VA+K+L    +    V  ++ +E + +K   H HI++L  +    + + +V+E    G L
Sbjct: 400 VAIKVLKNADLDP-SVQSELIKEAEVMKKMDHMHIVRLIGLCEGET-MMLVLELAKLGPL 227

Query: 113 FDYICKNGRLDEKESRRLFQQILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLS 172
             ++ KN  L       L  Q+  G++Y   +  VHRDL   N+LL     AKI+DFG+S
Sbjct: 226 NKFLPKNKHLPLWNILELMWQVSQGMEYLEANKFVHRDLAARNILLCDEHFAKISDFGMS 47

Query: 173 NMMS 176
             +S
Sbjct: 46  KTLS 35
>07940
          Length = 1336

 Score = 55.1 bits (131), Expect = 7e-08,   Method: Compositional matrix adjust.
 Identities = 34/106 (32%), Positives = 52/106 (49%), Gaps = 4/106 (3%)
 Frame = -3

Query: 133 QILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGS---PN 189
           Q+  G++Y      +HRDL   NVL+      KIADFGL+  +   ++ R +        
Sbjct: 323 QVARGMEYLASKQCIHRDLAARNVLVAEEYVLKIADFGLTRNLQQFDYYRKTTDGRLPVK 144

Query: 190 YAAPEVISGRLYAGPEVDIWSSGVILYALLC-GTLPFDDDHVPTLF 234
           + APE +  R Y   + D+WS GV+L+ +   G  P+    V  LF
Sbjct: 143 WMAPEALFDRKYTS-KSDVWSYGVLLWEIFTLGGNPYPSVPVEDLF 9
>12672
          Length = 773

 Score = 52.4 bits (124), Expect = 5e-07,   Method: Compositional matrix adjust.
 Identities = 31/103 (30%), Positives = 55/103 (53%), Gaps = 5/103 (4%)
 Frame = +3

Query: 129 RLFQQILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFG--LSNMMSDGEFLRTSC- 185
           ++ +   SG+ Y + +  VHRD+K  N+LLD+   AK+ DF   +S    +G+ ++ +  
Sbjct: 3   KIVKGTASGIQYLNDNGHVHRDIKTANILLDSEYTAKVGDFATVVSAPSGEGKTVQNASV 182

Query: 186 --GSPNYAAPEVISGRLYAGPEVDIWSSGVILYALLCGTLPFD 226
             G+  Y APE I        ++D +S GV+L  ++ G +  D
Sbjct: 183 VIGTAAYLAPEAI--HFDVSTKLDSYSFGVVLLEVITGLVAQD 305
>28157
          Length = 400

 Score = 52.4 bits (124), Expect = 5e-07,   Method: Compositional matrix adjust.
 Identities = 34/106 (32%), Positives = 52/106 (49%), Gaps = 7/106 (6%)
 Frame = +3

Query: 74  REIQNLKLFRHPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNG---RLDEKESRRL 130
           +E++ L    HP+I+ LY        + +VMEY  GG L++ +  +G   +     +   
Sbjct: 57  QELKQLSRVSHPNIVCLYGACRD-HPVCLVMEYAEGGSLYNVLHGSGPQPQYTAAHAMNW 233

Query: 131 FQQILSGVDYCHR---HMVVHRDLKPENVLL-DAHMNAKIADFGLS 172
             Q   GV+Y H      ++HRDLKP N+LL       KI DFG +
Sbjct: 234 LLQCALGVEYLHGMKPKALIHRDLKPPNLLLIQCGTKLKICDFGTA 371
>03508
          Length = 1463

 Score = 52.0 bits (123), Expect = 7e-07,   Method: Compositional matrix adjust.
 Identities = 26/94 (27%), Positives = 48/94 (51%), Gaps = 2/94 (2%)
 Frame = +1

Query: 128 RRLFQQILSGVDYCHRHMVVHRDLKPENVLLDAHMNAK--IADFGLSNMMSDGEFLRTSC 185
           R    +++  +D+CH   ++HRD+KP NV++D H N K  + D+GL+     G       
Sbjct: 880 RFYLYELMKALDFCHSMGIMHRDVKPHNVMID-HENKKLRLIDWGLAEFYHPGMEYNVRV 1056

Query: 186 GSPNYAAPEVISGRLYAGPEVDIWSSGVILYALL 219
            S  +  PE++         +D+WS G +  +++
Sbjct: 1057ASRYFKGPELLLDYQMYDYSLDMWSLGCMFASMI 1158
>37602
          Length = 804

 Score = 50.8 bits (120), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 25/70 (35%), Positives = 39/70 (55%)
 Frame = -1

Query: 100 IFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVDYCHRHMVVHRDLKPENVLLD 159
           +++ MEY  GG + D     G L E +   + ++ L G+ Y HR   +HRD+K  N+LL 
Sbjct: 294 LWIAMEYCGGGSMQDIYHVTGPLTEPQIAFVCRETLKGLHYLHRRGKMHRDIKGANILLT 115

Query: 160 AHMNAKIADF 169
              + K+ADF
Sbjct: 114 EEGDVKLADF 85
>00715
          Length = 1788

 Score = 50.4 bits (119), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 50/203 (24%), Positives = 83/203 (40%), Gaps = 29/203 (14%)
 Frame = +1

Query: 53  VAVKILNRQKIRSLDVVGKIRREIQNLKL-FRHPHIIKLYQVIST---PSDIFMVMEYVS 108
           VAVKI +++      +      E+   +   RH +++ +    S        ++ MEYV 
Sbjct: 7   VAVKIYHKRSSNPRALRQSYSNELLAFRCGLRHVNVVSILGATSLHRFEDGAWLAMEYV- 183

Query: 109 GGELFDYICKNGRLDEKESRRL--FQQILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKI 166
           G      I  + + D   S RL    Q+  G+ Y H   +VH DLKP N LL   +  +I
Sbjct: 184 GPLNLQTILNDHQQDIDSSMRLSLALQMARGLHYLHSINIVHLDLKPANCLLTRDLKLRI 363

Query: 167 ADFGLSNMMS-----------------------DGEFLRTSCGSPNYAAPEVISGRLYAG 203
           ADFG  + ++                        G +     G+  Y APE++ G L   
Sbjct: 364 ADFGCCHQLTPTGLDMGEREGGMAGNELELTPVQGAWKNELAGTLAYRAPELLKG-LQPS 540

Query: 204 PEVDIWSSGVILYALLCGTLPFD 226
              D++S G+ L+ +     P++
Sbjct: 541 VRSDVYSLGITLWQMCTRQGPYE 609
>17300
          Length = 480

 Score = 48.5 bits (114), Expect = 7e-06,   Method: Composition-based stats.
 Identities = 28/85 (32%), Positives = 47/85 (55%), Gaps = 6/85 (7%)
 Frame = +1

Query: 147 VHRDLKPENVLLDAHMNAKIADFGLSNMM----SDGEFLRTSCGSP-NYAAPEVISGRLY 201
           VHRDL   N+L++  +  K+ADFGLS  +    ++G +       P  + APE I+ R +
Sbjct: 40  VHRDLAARNILVNEILVCKVADFGLSREIESDTTEGAYTTKGGKIPVRWTAPEAIAYRKF 219

Query: 202 AGPEVDIWSSGVILYALLC-GTLPF 225
                D+WS GV+++ ++  G  P+
Sbjct: 220 TSAS-DVWSFGVVMWEVMSYGERPY 291
>07291
          Length = 833

 Score = 47.4 bits (111), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 31/115 (26%), Positives = 57/115 (49%), Gaps = 6/115 (5%)
 Frame = +1

Query: 132 QQILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSP--- 188
           +QI  G+ Y     VVHR+L   N ++      +++D+G++  +    +  T+  SP   
Sbjct: 70  RQIADGMAYLQEVKVVHRNLAARNCIVTEDGRLQLSDYGVTGSLFPQSYY-TADDSPARD 246

Query: 189 --NYAAPEVISGRLYAGPEVDIWSSGVILYALLC-GTLPFDDDHVPTLFKKICDG 240
              + APE I    ++  + D+W+ GV+L+ LL  G  P+ D    +L   + +G
Sbjct: 247 LVKWMAPETIDNFHFSS-KSDVWAFGVVLWELLTRGITPYPDVENSSLLPYLKEG 408
>04138
          Length = 800

 Score = 47.4 bits (111), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 51/188 (27%), Positives = 79/188 (42%), Gaps = 23/188 (12%)
 Frame = +1

Query: 140 YCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPN---------- 189
           Y HR+ ++HRD+K  N+L+      K+ADFGL+   S       +   PN          
Sbjct: 58  YIHRNKILHRDMKAANILITKQGVLKLADFGLARAFS------VNLRQPNRYTNRVVTLW 219

Query: 190 YAAPEVISGRLYAGPEVDIWSSGVILYAL------LCGTLPFDDDHVPTLFKKICDGIFY 243
           Y  PE++ G       +D W +G I+  +      + GT    + +  TL  ++C  I  
Sbjct: 220 YRPPELLLGDRNYSTAIDQWGAGCIMAEMWTRNPIMQGT---TEQNQLTLITQLCGSI-- 384

Query: 244 TPQYLNPSVISLLKHMLQVDPMKRAAIKDIREHEW-------FKQDLPKYLFPEDPSYSS 296
           TP+   P V  L  +  Q+     A  K+I    +       +  DL + L   DPS   
Sbjct: 385 TPEVW-PGVTQLSMYH-QIKGALAAGRKNIIRDRFARILKDPYGLDLFERLLKMDPSQRI 558

Query: 297 TMIDDEAL 304
           +   DEAL
Sbjct: 559 SA--DEAL 576
>07836
          Length = 1478

 Score = 47.0 bits (110), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 46/191 (24%), Positives = 83/191 (43%), Gaps = 22/191 (11%)
 Frame = -1

Query: 50   GHKVAVKILNRQKIRSLDVVGKIRREIQNLKLFRHPHIIKLYQV----ISTPSDIFMVME 105
            G  VAVKI    +  S         E+    L RH +I+           + + +F++ +
Sbjct: 1478 GENVAVKIFFTTEEASWFR----ETELYQTVLLRHENILGFIAADIKGTGSWTQLFLITD 1311

Query: 106  YVSGGELFDYICKNGRLDEKESRRLFQQILSGVDYCHRHM--------VVHRDLKPENVL 157
            Y   G L DY+     LD  E   L    + G+ + H  +        + HRD+K +N+L
Sbjct: 1310 YHENGSLHDYLLSR-VLDSSEMLALAHSAICGLAHLHIEIFGTRGKPAIAHRDIKSKNIL 1134

Query: 158  LDAHMNAKIADFGLS-NMMSDGEFLRTS----CGSPNYAAPEVISGRLY-----AGPEVD 207
            +  +    IAD GL+   +S+   +  +     G+  Y APEV+   L      A  + D
Sbjct: 1133 VKKNGTCCIADLGLAVRYISESNEVDVAPNPRQGTKRYMAPEVLEMLLNVKNFDAFKQAD 954

Query: 208  IWSSGVILYAL 218
            +++ G++++ +
Sbjct: 953  MYAFGLVMWEI 921
>17722
          Length = 680

 Score = 45.4 bits (106), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 25/80 (31%), Positives = 43/80 (53%), Gaps = 5/80 (6%)
 Frame = -3

Query: 206 VDIWSSGVILYALLCGTLPFDDDHVPTLFKKICDGIFYTPQYLNPSVISLLKHMLQVDPM 265
           VD W +GV++Y ++CG LPF +     LF+ I       P+ L+    +LL  +L  +P 
Sbjct: 678 VDWWGTGVVMYEMMCGRLPFYNRDHDVLFELILLQNVKFPRNLSEEAKTLLSGLLAKNPK 499

Query: 266 KR-----AAIKDIREHEWFK 280
           +R     A + +I+ H +F+
Sbjct: 498 RRLGGSEADVTEIKTHPFFQ 439
>08294
          Length = 1849

 Score = 45.4 bits (106), Expect = 6e-05,   Method: Compositional matrix adjust.
 Identities = 51/208 (24%), Positives = 88/208 (42%), Gaps = 19/208 (9%)
 Frame = +2

Query: 85   PHIIKLYQVISTPSDIFMVMEYVSGGELFDYICK----NGR--------LDEKESRRLFQ 132
            P+I+    V       F++ EY   G+L  ++      NGR        L   +   + Q
Sbjct: 887  PNIVHFMGVCREAEPHFLITEYCDWGDLKQFLLATRNDNGRGRGTRVPALALSQKLGMGQ 1066

Query: 133  QILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEF--LRTSCGSPNY 190
            Q+ +G++      +VH DL   NVLL + M  K+A   LS  +   E+  L        +
Sbjct: 1067 QVAAGMEALSNQGLVHGDLAARNVLLTSRMQLKVARPALSGDVYASEYYPLHQRLVPLRW 1246

Query: 191  AAPEVISGRLYAGPEVDIWSSGVILYALL-CGTLPF----DDDHVPTLFKKICDGIFYTP 245
              PE +     A    D+W+ GV L+ +L    LP+    D++ + +L  +       +P
Sbjct: 1247 LPPEGVLED-SATTCGDVWAFGVFLWEVLQLADLPYRLMSDEEVLRSL--QHSQAALDSP 1417

Query: 246  QYLNPSVISLLKHMLQVDPMKRAAIKDI 273
                P+++SLL+      P +R    +I
Sbjct: 1418 DA-PPALLSLLQRCTAQQPSQRPPFSEI 1498
>17253
          Length = 483

 Score = 45.4 bits (106), Expect = 6e-05,   Method: Composition-based stats.
 Identities = 27/110 (24%), Positives = 50/110 (45%), Gaps = 12/110 (10%)
 Frame = -1

Query: 80  KLFRHPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICK---------NGRLDEKESRRL 130
           KL RHP+++      +      ++ME+   G+L  ++ K             ++  +R  
Sbjct: 381 KLPRHPNVVSFMGCCTMSDPALILMEFCCHGDLLSFLRKRRPDRTVFLTSTANDLTARDF 202

Query: 131 FQ---QILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSD 177
           F     +  G+ +   + +VHRD+   NVL+      K++DFGLS  + D
Sbjct: 201 FSFALHVARGMAHVANNKIVHRDVAARNVLISERNVCKVSDFGLSRRVGD 52
>22005
          Length = 873

 Score = 45.4 bits (106), Expect = 6e-05,   Method: Compositional matrix adjust.
 Identities = 50/204 (24%), Positives = 83/204 (40%), Gaps = 49/204 (24%)
 Frame = +1

Query: 65  SLDVVGKIRREIQNLKLFRHPHIIKLYQVISTPSDIFMVMEYVSGGELFDYI-------- 116
           S D+     RE   +  F HP+I+KL  V +    + ++ E++S G+L D++        
Sbjct: 130 SEDLQSDFEREASLMADFDHPNIVKLLGVCAIGKPMCLLFEFMSKGDLNDFLRLCSPENY 309

Query: 117 --------------------------CK----------NGRLDEKESRRLFQQILSGVDY 140
                                     C+          +G L  K+   + QQI +G+ Y
Sbjct: 310 NLPVSRSQNLVVDLEDGLRVEVEAEECEKDTQSEDRDCSGMLXTKDQLYISQQISAGMAY 489

Query: 141 CHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYAAP---EVIS 197
             +   VHRDL    V       + I+DFGL+  +   ++ R   GS   A P     + 
Sbjct: 490 LAQKDYVHRDLATRTVXS-RTT*S*ISDFGLARSVHSVDYYR---GSEQDAIPIRWMPLE 657

Query: 198 GRLYA--GPEVDIWSSGVILYALL 219
             LY+    + D+WS GV+L+ +L
Sbjct: 658 AILYSKFSTQSDVWSFGVVLWEIL 729
>29590
          Length = 320

 Score = 44.7 bits (104), Expect = 1e-04,   Method: Composition-based stats.
 Identities = 21/58 (36%), Positives = 33/58 (56%)
 Frame = +3

Query: 168 DFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAGPEVDIWSSGVILYALLCGTLPF 225
           D G + + + GE +R   G+P+Y APEV+     +  + D+WS GV+ Y +L    PF
Sbjct: 6   DLGFACLTNTGEDIRDIIGTPDYVAPEVLDYEPLS-IQTDMWSLGVLSYVMLTACSPF 176
>31489
          Length = 329

 Score = 44.3 bits (103), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 31/88 (35%), Positives = 46/88 (52%), Gaps = 6/88 (6%)
 Frame = +3

Query: 76  IQNLKLFRHPHIIKLYQVISTP------SDIFMVMEYVSGGELFDYICKNGRLDEKESRR 129
           I+ LK F+H +II + +++          DI +V + +   +L   I  +  L E+  R 
Sbjct: 3   IKILKHFKHDNIISIREILKPKDSYHDFKDIHVVFDLMES-DLHRIIYSDQPLTEEHIRY 179

Query: 130 LFQQILSGVDYCHRHMVVHRDLKPENVL 157
              QIL G+ Y H   VVHRDLKP N+L
Sbjct: 180 FLYQILRGLKYIHSANVVHRDLKPSNLL 263
>26009
          Length = 886

 Score = 43.9 bits (102), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 16/41 (39%), Positives = 29/41 (70%)
 Frame = +3

Query: 118 KNGRLDEKESRRLFQQILSGVDYCHRHMVVHRDLKPENVLL 158
           +N     +E++ + +Q++S +D+ H   +VHRD+KPENVL+
Sbjct: 690 RNKACGSREAKSVMKQLVSALDFMHSKQLVHRDIKPENVLI 812
>18481
          Length = 437

 Score = 43.5 bits (101), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 35/102 (34%), Positives = 51/102 (50%), Gaps = 5/102 (4%)
 Frame = -1

Query: 83  RHPHIIKLYQVISTPSDIFMVMEYV--SGGELFDYICKNGRLDEKESRRLFQQILSGVDY 140
           RHP +  +Y   +      +VME +  S  ELF  ICK  R   K    +  Q+LS +++
Sbjct: 323 RHPGLPTMYHYGTEKHFNALVMELLGPSLEELF-VICKR-RFTLKTILMVSDQLLSRLEF 150

Query: 141 CHRHMVVHRDLKPENVLLDAHMNAK---IADFGLSNMMSDGE 179
            H+   +HRDLKP+N L+    +     I DFGLS    D +
Sbjct: 149 IHQKCFIHRDLKPDNFLMGLGRHCHRLYIIDFGLSKRYKDTQ 24
>25019
          Length = 730

 Score = 43.5 bits (101), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 25/60 (41%), Positives = 33/60 (55%), Gaps = 1/60 (1%)
 Frame = +3

Query: 154 ENVLLDAHMNAKIADFGLSN-MMSDGEFLRTSCGSPNYAAPEVISGRLYAGPEVDIWSSG 212
           ENVLLD   + K+ DFGL    ++      T CG+  Y APE+++ R   G  VD WS G
Sbjct: 261 ENVLLDKDGHVKLTDFGLCKEAITGTRVTHTFCGTIEYMAPEILT-RTGHGKAVDWWSLG 437
>16708
          Length = 1397

 Score = 43.5 bits (101), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 17/42 (40%), Positives = 29/42 (69%)
 Frame = -1

Query: 133  QILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNM 174
            Q +  +++ H   VVH D+K +NVL+DAH N K+ D+G++ +
Sbjct: 1070 QXVCALEHIHELGVVHMDVKADNVLVDAHGNCKLTDYGIAQL 945
>28638
          Length = 1458

 Score = 43.5 bits (101), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 34/103 (33%), Positives = 51/103 (49%), Gaps = 4/103 (3%)
 Frame = -1

Query: 127 SRRLFQQILSGVDYCH--RHMVVHRDLKPENVLL--DAHMNAKIADFGLSNMMSDGEFLR 182
           +R+  QQ+ + + +       ++H DLKPEN+LL        KI DFG S  +  G+ + 
Sbjct: 831 TRKFAQQLCTALLFLATPEMNIIHCDLKPENILLCNPKRSAIKIVDFGSSCQL--GQRIY 658

Query: 183 TSCGSPNYAAPEVISGRLYAGPEVDIWSSGVILYALLCGTLPF 225
               S  Y +PEV+ G  Y    +D+WS G IL  +  G  P 
Sbjct: 657 QYIQSRFYRSPEVLLGVPY-DLAIDMWSLGCILVEMHTGEPPL 532
>20640
          Length = 1492

 Score = 42.7 bits (99), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 35/134 (26%), Positives = 60/134 (44%), Gaps = 7/134 (5%)
 Frame = +1

Query: 147 VHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYAAP---EVISGRLYA- 202
           VHRDL   N L+   +  KI+DFGL+  +   ++ R   GS + A P     +   LY  
Sbjct: 10  VHRDLATRNCLVGHDLVVKISDFGLARSVHSVDYYR---GSEHDAIPIRWMPLEAILYNK 180

Query: 203 -GPEVDIWSSGVILYALLCGTL-PFDDDHVPTLFKKICDG-IFYTPQYLNPSVISLLKHM 259
              + D+WS GV+L+ +    L P+       + + + +G +   P+   P +  L+K  
Sbjct: 181 FSTQSDVWSFGVVLWEIFAFALQPYYGLTHEEVVRFVKEGKVLACPERTPPPMYELMKQC 360

Query: 260 LQVDPMKRAAIKDI 273
               P  R +   +
Sbjct: 361 WHRRPATRPSFHTL 402
>27274
          Length = 396

 Score = 41.2 bits (95), Expect = 0.001,   Method: Composition-based stats.
 Identities = 31/124 (25%), Positives = 56/124 (45%), Gaps = 21/124 (16%)
 Frame = -1

Query: 194 EVISGRLYAGPEVDIWSSGVILYALLCGTLPFDDDH----------------VPTLFKKI 237
           E++ G+ + GP VD+WS G++L+ LL G +PF+ +                 +    + +
Sbjct: 375 ELLRGQQH-GPTVDMWSLGILLHELLSGHVPFEPERGSRQMARNMMAVYAQIIRGSSRDV 199

Query: 238 CDGIFYTPQYLNPSVISLLKHMLQVDPMKRAAIKDIREHEWFKQDLPKYLF-----PEDP 292
           CDG+      L+      L+ ++Q++  KR   +    H W  +     LF     P+D 
Sbjct: 198 CDGL-----ALSTHGADFLRRLVQLEDTKRLTSQQAFSHPWIAR*RHNNLFTNFGSPDDV 34

Query: 293 SYSS 296
           + SS
Sbjct: 33  TASS 22
>32000
          Length = 644

 Score = 40.4 bits (93), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 43/147 (29%), Positives = 64/147 (43%), Gaps = 32/147 (21%)
 Frame = -1

Query: 165 KIADFGLSNMMSDGEFLRT---SCGSPNYAAPEVISG-RLYAGPEVDIWSSGVILYALLC 220
           KIADFGL+ +   G  +RT      +  Y APE++ G R Y+ P VDIWS G I   ++ 
Sbjct: 569 KIADFGLARVF--GLPVRTYTHEVITLWYRAPEILLGCRFYSVP-VDIWSLGCIFVEMMT 399

Query: 221 --GTLPFDD--DHVPTLFK-------KICDGIFYTPQY-----------------LNPSV 252
                P D   D +  +F+       K+  G+   P Y                 L+   
Sbjct: 398 RRALFPGDSEIDQLYRIFRTLGTPDEKVWPGVSKLPDYKPTFPKWPLKNLETVVSLSKVG 219

Query: 253 ISLLKHMLQVDPMKRAAIKDIREHEWF 279
           + LLK ML  +P +R + +    H +F
Sbjct: 218 LDLLKRMLTYNPNRRISARSAMRHPYF 138
>31120
          Length = 439

 Score = 38.9 bits (89), Expect = 0.005,   Method: Composition-based stats.
 Identities = 18/42 (42%), Positives = 25/42 (59%)
 Frame = +1

Query: 194 EVISGRLYAGPEVDIWSSGVILYALLCGTLPFDDDHVPTLFK 235
           EV+ G  Y     D WS GVIL+ +L G +PFDD ++  L +
Sbjct: 1   EVVCGVPYDPKMADAWSLGVILFIMLNGKMPFDDSNLNKLLE 126
>32957
          Length = 645

 Score = 38.5 bits (88), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 23/51 (45%), Positives = 28/51 (54%)
 Frame = +3

Query: 169 FGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAGPEVDIWSSGVILYALL 219
           F L    S G   RT CG+  Y APEV   + Y G EVD W  G++L+ LL
Sbjct: 3   FALCVEKSGGR-TRTFCGTREYMAPEVHERKEY-GKEVDWWGLGILLHELL 149
>18996
          Length = 491

 Score = 38.1 bits (87), Expect = 0.009,   Method: Compositional matrix adjust.
 Identities = 27/82 (32%), Positives = 42/82 (51%), Gaps = 4/82 (4%)
 Frame = +2

Query: 147 VHRDLKPENVLLDAHMNAKIADFGLSNMM-SDGEFLRTSCGS--PNYAAPEVISGRLYAG 203
           +HRDL   N+L+D     KI+DFGL+    +DG +   S       + +PE I    ++ 
Sbjct: 2   IHRDLAARNILVDRSC-VKISDFGLAQFANADGYYYGISQRDIPIKWYSPEAIETCKFSS 178

Query: 204 PEVDIWSSGVILYALLC-GTLP 224
              D+WS GV L+ +   G +P
Sbjct: 179 -YSDVWSYGVTLFEMFSRGEIP 241
>36481
          Length = 806

 Score = 35.4 bits (80), Expect = 0.060,   Method: Compositional matrix adjust.
 Identities = 33/128 (25%), Positives = 58/128 (45%), Gaps = 17/128 (13%)
 Frame = +2

Query: 48  LTGHKVAVKIL-NRQKIRS-----LDVVGKIRRE--------IQNLKLF-RHPHIIKLYQ 92
           L G  +A+KI+ N  K R      ++V+ K+R +        +Q L  F  H H+   + 
Sbjct: 431 LKGDDIALKIIKNVDKYREAAKLEINVLEKLREKDPHAKHMCVQMLDWFDYHGHVCISFH 610

Query: 93  VISTPSDIFMVMEYVSGGELFDYICKN--GRLDEKESRRLFQQILSGVDYCHRHMVVHRD 150
           ++              G  +FD++  N  G    ++ R +  Q+   V++ H + + H D
Sbjct: 611 ML--------------GLSVFDFLKDNSYGAYPIEQVRHISYQLCYAVNFLHENQLTHTD 748

Query: 151 LKPENVLL 158
           LKPEN+L 
Sbjct: 749 LKPENILF 772
>21418
          Length = 831

 Score = 34.7 bits (78), Expect = 0.11,   Method: Compositional matrix adjust.
 Identities = 17/42 (40%), Positives = 25/42 (59%), Gaps = 2/42 (4%)
 Frame = +2

Query: 242 FYTPQYLNPSVIS--LLKHMLQVDPMKRAAIKDIREHEWFKQ 281
           F  P++ N S  +  L+K ML VDP KR  I+D+  ++W  Q
Sbjct: 35  FPDPEWTNVSQAAKDLIKGMLNVDPSKRLCIEDVLRNKWIAQ 160
>36002
          Length = 253

 Score = 33.9 bits (76), Expect = 0.20,   Method: Compositional matrix adjust.
 Identities = 16/50 (32%), Positives = 28/50 (56%), Gaps = 4/50 (8%)
 Frame = +1

Query: 233 LFKKICDGIFYTPQY----LNPSVISLLKHMLQVDPMKRAAIKDIREHEW 278
           LF +I DG ++ P      ++ S   L++H+L  +P KR +  D+ +H W
Sbjct: 58  LFNRIQDGNYFFPSMEWSAISSSAKDLIRHLLVREPRKRYSAADVLKHPW 207
>21800
          Length = 855

 Score = 33.1 bits (74), Expect = 0.34,   Method: Compositional matrix adjust.
 Identities = 12/32 (37%), Positives = 24/32 (75%), Gaps = 1/32 (3%)
 Frame = +2

Query: 128 RRLFQQILSGVDYCH-RHMVVHRDLKPENVLL 158
           + + +Q+L G++Y H +  ++H D+KPEN+L+
Sbjct: 641 KLIIRQVLEGLNYLHAKCNIIHTDIKPENILI 736
>01106
          Length = 878

 Score = 32.3 bits (72), Expect = 0.54,   Method: Compositional matrix adjust.
 Identities = 12/30 (40%), Positives = 22/30 (73%), Gaps = 1/30 (3%)
 Frame = +3

Query: 130 LFQQILSGVDYCH-RHMVVHRDLKPENVLL 158
           + +Q+L G+ Y H +  ++H D+KPEN+L+
Sbjct: 660 IIRQVLEGLSYMHAKCRIIHTDIKPENILI 749
>29360
          Length = 363

 Score = 30.8 bits (68), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 19/75 (25%), Positives = 40/75 (53%), Gaps = 2/75 (2%)
 Frame = +3

Query: 86  HIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGR--LDEKESRRLFQQILSGVDYCHR 143
           + ++ ++     +   +V E +    L+D++ +N    L  K  R + QQ+L+ +    +
Sbjct: 138 NFVRAFECFQHKNHTCLVFEMLEQN-LYDFLKQNKFQPLPLKYIRPITQQVLTALRKLKQ 314

Query: 144 HMVVHRDLKPENVLL 158
             ++H DLKPEN++L
Sbjct: 315 LGLIHADLKPENIML 359
>17516
          Length = 453

 Score = 30.0 bits (66), Expect = 2.6,   Method: Composition-based stats.
 Identities = 29/104 (27%), Positives = 46/104 (44%), Gaps = 11/104 (10%)
 Frame = -3

Query: 183 TSCGSPNYAAPEVISGRLYAGPEVDIWSSGVILYALLCGTLPFDDDHVPT-LFKKICDGI 241
           T  G+P Y APEV+  +     + D++S  +IL+ L  G      DH+ + LF ++ D +
Sbjct: 442 TLAGTPVYMAPEVLLQKGQYDMKADVYSLAIILWELWYGQDA--ADHISSHLFGRLEDAV 269

Query: 242 FYTPQYLNPSV----------ISLLKHMLQVDPMKRAAIKDIRE 275
                 L PSV          + LL+   +    KR   +D  E
Sbjct: 268 ---QAGLRPSVTMTCKPPDDWLKLLQSGWEFHASKRPTSRDAAE 146
>00638
          Length = 1595

 Score = 29.3 bits (64), Expect = 4.0,   Method: Compositional matrix adjust.
 Identities = 10/32 (31%), Positives = 20/32 (62%)
 Frame = +2

Query: 128 RRLFQQILSGVDYCHRHMVVHRDLKPENVLLD 159
           R    +++  +D+CH   ++HRD+KP   L++
Sbjct: 425 RFYLYELMKALDFCHSMGIMHRDVKPSPPLVN 520
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|21312750|ref|NP_080697.1| E-1 enzyme [Mus musculus]
         (257 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

31424                                                                 124   5e-29
37885                                                                  27   7.5  
>31424
          Length = 832

 Score =  124 bits (310), Expect = 5e-29,   Method: Compositional matrix adjust.
 Identities = 65/202 (32%), Positives = 110/202 (54%), Gaps = 2/202 (0%)
 Frame = -2

Query: 54  QDVSLLRK--QAEEDAHLDGAVPIPVASGSDLQQMIQAVVDNVYWQMSHDRKTTALKQLQ 111
           +DV+ LR+  Q ++++  +GAV IP A+    +++I+AVV +V WQ+  +R++  L Q  
Sbjct: 693 KDVAGLRELSQKDKESGAEGAVQIPAAADGK-EEVIKAVVASVKWQVDSERESPELTQFH 517

Query: 112 GHMWKAAFTAGRMKAEFFADVVPAVRRWREAGMKVYIYSSRSVEAQKLLFGHSTEGDILE 171
            H+W+  +  G +K + F DV P ++   E G  ++++S  + + QK+ F ++ +GD+ +
Sbjct: 516 HHVWRHGYEFGSLKGQVFEDVPPMLQMLSEEGFTLFVFSDGNADLQKMFFANTEKGDLTQ 337

Query: 172 LIDGHFDTKIGHKVDSESYRKIADSIGCSTNNILFLTDXXXXXXXXXXXXXXXXXXXRPG 231
           L   +FD   G K +SE+Y K+A  I    ++ILFLTD                   R G
Sbjct: 336 LFSNYFDKSFGSKTESETYVKLATEIKFQASDILFLTDTPEEAAAAHTAGFRCALVIREG 157

Query: 232 NAGLTDDEKTYYNLITSFSELY 253
           N  LTD+    +  I  F ELY
Sbjct: 156 NPDLTDEHLQNFACIEHFDELY 91
>37885
          Length = 722

 Score = 26.9 bits (58), Expect = 7.5,   Method: Compositional matrix adjust.
 Identities = 16/45 (35%), Positives = 19/45 (42%)
 Frame = -2

Query: 62  QAEEDAHLDGAVPIPVASGSDLQQMIQAVVDNVYWQMSHDRKTTA 106
           Q EED H D     P A G D+Q +I     N     + DR   A
Sbjct: 163 QDEEDEHQDELSDQPAAGGGDIQLLINQTRHNSSTLTADDRTCHA 29
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6678137|ref|NP_033301.1| signal recognition particle
receptor, B subunit [Mus musculus]
         (269 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

28208                                                                 124   5e-29
09827                                                                  42   4e-04
08153                                                                  39   0.002
18173                                                                  31   0.48 
34767                                                                  30   0.81 
>28208
          Length = 523

 Score =  124 bits (310), Expect = 5e-29,   Method: Compositional matrix adjust.
 Identities = 59/128 (46%), Positives = 90/128 (70%), Gaps = 1/128 (0%)
 Frame = +2

Query: 143 SAAFQREVKDVAEFLYQVLIDSMALKNSPSLLIACNKQDIAMAKSAKLIQQQLEKELNTL 202
           +A  ++E+K+VAE+LY VL D +   N+P +LIACNKQD+ + K   LI + LEKE+NTL
Sbjct: 11  AATCRKEIKEVAEYLYTVLTDRVISHNAPPVLIACNKQDLTLCKGXTLINKMLEKEMNTL 190

Query: 203 RVTRSAAPSTLDSSSTAPAQLGKKGKEFEFSQL-PLKVEFLECSAKGGRGDTGSADIQDL 261
           RVTRSAA   +D++      LG++ ++F F+ L PL+V+F+ECSAK G+ +    D++ +
Sbjct: 191 RVTRSAALQGIDNTGNNNTFLGRRDRDFSFADLKPLRVDFVECSAK-GKDENSEGDLKPV 367

Query: 262 EKWLAKIA 269
             W+A+IA
Sbjct: 368 MDWMAQIA 391
>09827
          Length = 1201

 Score = 41.6 bits (96), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 40/142 (28%), Positives = 75/142 (52%)
 Frame = -3

Query: 54   FIWSRKSSQRAVLFVGLCDSGKTLLFVRLLTGQYRDTQTSITDSSAIYKVNNNRGNSLTL 113
            F++ +K  +  +L VGL  +GKT +  +L  G+   T  +I  +    +  N    S T+
Sbjct: 1133 FMFGKKDMR--ILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKN---ISFTV 969

Query: 114  IDLPGHESLRFQLLDRFKSSARAVVFVVDSAAFQREVKDVAEFLYQVLIDSMALKNSPSL 173
             D+ G + +R  L   +  + + ++FVVDS   +R V++  E L ++L +   L+++  L
Sbjct: 968  WDVGGQDKIR-PLWRHYFQNTQGLIFVVDSNDKER-VQEAREELTRMLNED-ELRDA-VL 801

Query: 174  LIACNKQDIAMAKSAKLIQQQL 195
            L+  NKQD+  A +   I ++L
Sbjct: 800  LVFANKQDLPHAMATAEITEKL 735
>08153
          Length = 1703

 Score = 38.9 bits (89), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 38/131 (29%), Positives = 67/131 (51%)
 Frame = +1

Query: 65  VLFVGLCDSGKTLLFVRLLTGQYRDTQTSITDSSAIYKVNNNRGNSLTLIDLPGHESLRF 124
           +L VGL  +GKT +  +L  G+   T  +I  +    +  N    S T+ D+ G + +R 
Sbjct: 91  ILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKN---ISFTVWDVGGQDKIR- 258

Query: 125 QLLDRFKSSARAVVFVVDSAAFQREVKDVAEFLYQVLIDSMALKNSPSLLIACNKQDIAM 184
            L   +  + + ++FVVDS   +R + +  E L ++L +   L+++  L+ A NKQD+  
Sbjct: 259 PLWRHYFQNTQGLIFVVDSNDRER-INEAKEELARML-NEDDLRDAIILVFA-NKQDLPN 429

Query: 185 AKSAKLIQQQL 195
           A SA  +   L
Sbjct: 430 AYSASEVTAHL 462
>18173
          Length = 1308

 Score = 31.2 bits (69), Expect = 0.48,   Method: Compositional matrix adjust.
 Identities = 29/146 (19%), Positives = 57/146 (39%), Gaps = 9/146 (6%)
 Frame = +2

Query: 63  RAVLFVGLCDSGKTLLFVRLLTGQYRDTQTSITDSSAIYKVNNNRGNSLTLIDLPG---- 118
           R ++  G  + GK+    ++          + T  S      + + N   +ID PG    
Sbjct: 551 RTIIICGFPNVGKSSFINKVTNADVEVQPYAFTTKSLYVGHTDYKFNRYQVIDTPGILDH 730

Query: 119 ----HESLRFQLLDRFKSSARAVVFVVD-SAAFQREVKDVAEFLYQVLIDSMALKNSPSL 173
                 ++  Q +         V++V+D S   Q+ V++     + +   +   KN P L
Sbjct: 731 PMEDMNTIEMQAITALTHLKAIVLYVMDLSQQCQKTVEEQVSLFHSI---TPLFKNKP-L 898

Query: 174 LIACNKQDIAMAKSAKLIQQQLEKEL 199
           ++ CNK D+          QQL +++
Sbjct: 899 MVVCNKADVTTLADLAPDTQQLVRDM 976
>34767
          Length = 426

 Score = 30.4 bits (67), Expect = 0.81,   Method: Compositional matrix adjust.
 Identities = 22/73 (30%), Positives = 30/73 (41%), Gaps = 12/73 (16%)
 Frame = +3

Query: 62  QRAVLFVGLCDSGKTLLFVRLL--------TGQYRDTQTSITDSSAIYKVNNNRGNSLTL 113
           Q+A   V +C SG   L   +          G       S+ DSSAI  ++    NSL++
Sbjct: 90  QKATAVVSVCTSGSVTLPTAVPHSQCSQSSVGPPSHNTVSVADSSAITPIH----NSLSV 257

Query: 114 ID----LPGHESL 122
            D     P H SL
Sbjct: 258 ADSSASTPSHNSL 296
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|113205059|ref|NP_035862.2| nuclease sensitive element
binding protein 1 [Mus musculus]
         (322 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

11798                                                                 124   6e-29
00661                                                                  77   1e-14
23204                                                                  73   2e-13
35001                                                                  28   5.1  
>11798
          Length = 1642

 Score =  124 bits (310), Expect = 6e-29,   Method: Compositional matrix adjust.
 Identities = 58/78 (74%), Positives = 65/78 (83%)
 Frame = +2

Query: 49  DKKVIATKVLGTVKWFNVRNGYGFINRNDTKEDVFVHQTAIKKNNPRKYLRSVGDGETVE 108
           +KKVIA K+ GTVKWFNV++GYGFINR+DT EDVFVHQTAI KNNP+KYLRSVGD E VE
Sbjct: 242 EKKVIAEKIKGTVKWFNVKSGYGFINRDDTNEDVFVHQTAIVKNNPKKYLRSVGDNEEVE 421

Query: 109 FDVVEGEKGAEAANVTGP 126
           FDVVEGEKG +      P
Sbjct: 422 FDVVEGEKGTKRPTSLAP 475

 Score = 42.4 bits (98), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 20/24 (83%), Positives = 20/24 (83%)
 Frame = +1

Query: 116 KGAEAANVTGPGGVPVQGSKYAAD 139
           KG EAANVTGP G  VQGSKYAAD
Sbjct: 442 KGNEAANVTGPNGTNVQGSKYAAD 513
>00661
          Length = 2118

 Score = 77.0 bits (188), Expect = 1e-14,   Method: Compositional matrix adjust.
 Identities = 39/76 (51%), Positives = 47/76 (61%)
 Frame = +3

Query: 59  GTVKWFNVRNGYGFINRNDTKEDVFVHQTAIKKNNPRKYLRSVGDGETVEFDVVEGEKGA 118
           G VKWFNV  G+GFI  +D   DVFVHQ+AI K+      RS+GD E VEF  V   KG 
Sbjct: 24  GKVKWFNVAKGWGFITPDDGTTDVFVHQSAIHKSG----FRSLGDDEVVEFHTVTSAKGY 191

Query: 119 EAANVTGPGGVPVQGS 134
           EA +V+  GG   +GS
Sbjct: 192 EARDVSAVGGAECRGS 239
>23204
          Length = 1566

 Score = 72.8 bits (177), Expect = 2e-13,   Method: Compositional matrix adjust.
 Identities = 37/76 (48%), Positives = 46/76 (60%)
 Frame = +1

Query: 59  GTVKWFNVRNGYGFINRNDTKEDVFVHQTAIKKNNPRKYLRSVGDGETVEFDVVEGEKGA 118
           G  KWFNV  G+GFI  +D  +DVFVHQ+ I K       RS+G+GE VEF+    +KG 
Sbjct: 181 GYCKWFNVAKGWGFITPDDQTQDVFVHQSTIYKAG----FRSLGEGEIVEFESKPSDKGV 348

Query: 119 EAANVTGPGGVPVQGS 134
           EA  V G GG   +GS
Sbjct: 349 EAVFVCGVGGAECRGS 396
>35001
          Length = 942

 Score = 28.1 bits (61), Expect = 5.1,   Method: Compositional matrix adjust.
 Identities = 12/47 (25%), Positives = 24/47 (51%)
 Frame = +1

Query: 65  NVRNGYGFINRNDTKEDVFVHQTAIKKNNPRKYLRSVGDGETVEFDV 111
           +++  +GFI R D   ++F H +  + N     +  +  G+ VEF +
Sbjct: 712 SMKESFGFIERADVVREIFFHYSEFRGN-----IEDLELGDDVEFSI 837
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|8567338|ref|NP_059505.1| coatomer protein complex,
subunit gamma isoform 1 [Mus musculus]
         (874 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

39334                                                                  96   7e-29
06441                                                                  30   6.0  
>39334
          Length = 432

 Score = 96.3 bits (238), Expect(3) = 7e-29,   Method: Composition-based stats.
 Identities = 44/82 (53%), Positives = 64/82 (78%), Gaps = 1/82 (1%)
 Frame = +1

Query: 794 IKTLEEAVGNIVKFLGMHPCERSDKVPENKNTHTLLLAGVFRGGHDILVRSRLLLLDT-V 852
           + TLEEA+ NI+++LG+ PCERSDKVPE K++HTL LAG++RGGHD LVRS+L L  + V
Sbjct: 145 MSTLEEAIKNIIQYLGLQPCERSDKVPEGKSSHTLYLAGMYRGGHDALVRSKLALDSSGV 324

Query: 853 TMQVTARSSEELPVDIILASVG 874
           TMQ+T RS++    +++  ++ 
Sbjct: 325 TMQLTVRSTDPSVSEVLATAIA 390

 Score = 39.7 bits (91), Expect(3) = 7e-29,   Method: Compositional matrix adjust.
 Identities = 18/21 (85%), Positives = 20/21 (95%)
 Frame = +2

Query: 752 VLEDLEVTVADHIQKVMKVNF 772
           VLED+EVTVADH+QKVMK NF
Sbjct: 17  VLEDVEVTVADHVQKVMKPNF 79

 Score = 30.8 bits (68), Expect(3) = 7e-29,   Method: Composition-based stats.
 Identities = 13/22 (59%), Positives = 17/22 (77%)
 Frame = +3

Query: 772 FEAAWDEVGDEFEKEETFTLST 793
           F A+W+EVG E E E+T+ LST
Sbjct: 78  FAASWEEVGTENELEDTYVLST 143
>06441
          Length = 1003

 Score = 29.6 bits (65), Expect = 6.0,   Method: Compositional matrix adjust.
 Identities = 15/48 (31%), Positives = 24/48 (50%)
 Frame = -2

Query: 667 NTLNDQTLENVTVQMEPTEAYEVLSYVPARSLPYNQPGTCYTLVALPT 714
           N  ND   ++VT      + Y    Y+P  +LP+  P +CY+ + L T
Sbjct: 753 NL*NDVNFKSVT------KLYYFFVYLPHLNLPFLSPSSCYSFLVLET 628
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|33667095|ref|NP_766604.2| vesicle amine transport
protein 1 homolog-like (T. californica) [Mus musculus]
         (417 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

05615                                                                 124   8e-29
25131                                                                  48   7e-06
18797                                                                  35   6e-04
21362                                                                  37   0.019
21879                                                                  30   2.0  
21872                                                                  28   6.1  
09000                                                                  28   6.7  
>05615
          Length = 1904

 Score =  124 bits (310), Expect = 8e-29,   Method: Compositional matrix adjust.
 Identities = 55/102 (53%), Positives = 76/102 (74%), Gaps = 2/102 (1%)
 Frame = +2

Query: 285 SFFSFAKS--WWQVEKVNPIKLYEENKVIAGFSLLNLLFKQGRSGLIRGVVEKLIGLYNQ 342
           S  +  KS  WWQV+KVNPIKL+++N+ + GF L  LLF+QG+   + GVV+KL+ L+ Q
Sbjct: 92  SHVNLTKSDQWWQVDKVNPIKLFDDNRSVGGFQLRRLLFRQGQHDYVHGVVDKLLELHGQ 271

Query: 343 KKIKPVVDSLWALEEVKEAMQRIHDRGNIGKLILDVEKTPTP 384
            KI+PV+DS+WA E+V E MQ++HDR NIGK++LD  K P P
Sbjct: 272 GKIRPVIDSVWAFEDVGEGMQKLHDRKNIGKILLDPSKEPEP 397
>25131
          Length = 982

 Score = 48.1 bits (113), Expect = 7e-06,   Method: Compositional matrix adjust.
 Identities = 24/75 (32%), Positives = 40/75 (53%), Gaps = 1/75 (1%)
 Frame = +2

Query: 97  PLVPGFECSGIVEALGDSVKGYEIGDRVMAFVNYNA-WAEVVCTPVEFVYKIPDDMSFSE 155
           P  PG + +G+VE++G  VK ++ GDR     +    + E   + V    ++ D +SFS+
Sbjct: 5   PYTPGSDAAGVVESVGXKVKDFKKGDRAYTIRSVTGTYGEYAVSEVVHTARLSDKLSFSQ 184

Query: 156 AAAFPMNFVTAYTML 170
            AA  + + TAY  L
Sbjct: 185 GAALGVPYYTAYRAL 229
>18797
          Length = 1159

 Score = 35.4 bits (80), Expect(2) = 6e-04,   Method: Compositional matrix adjust.
 Identities = 30/88 (34%), Positives = 42/88 (47%), Gaps = 4/88 (4%)
 Frame = -1

Query: 101 GFECSGIVEALGDSVKGYEIGDRVMAFVNYNAWAEVV---CTPVEF-VYKIPDDMSFSEA 156
           G + SGIV+ +G  V   + GD V+  +  +         C   EF V K P  +S  EA
Sbjct: 949 GRDVSGIVKDVGSRVSTVKEGDEVVGILPLDTTTSGCGEFCIFREFDVAKKPHRVSHEEA 770

Query: 157 AAFPMNFVTAYTMLFEIANLREGMSVLV 184
           AA   + V AYT L    ++  G SVL+
Sbjct: 769 AAVIGDAVRAYTALHYHTHVCAGDSVLI 686

 Score = 25.4 bits (54), Expect(2) = 6e-04,   Method: Compositional matrix adjust.
 Identities = 9/19 (47%), Positives = 14/19 (73%)
 Frame = -3

Query: 61   MPEPQDGELKIRVKACGLN 79
            +P  +D E+ ++VKACGL 
Sbjct: 1073 IPSLKDNEILVQVKACGLT 1017
>21362
          Length = 521

 Score = 36.6 bits (83), Expect = 0.019,   Method: Compositional matrix adjust.
 Identities = 29/92 (31%), Positives = 47/92 (51%), Gaps = 16/92 (17%)
 Frame = +2

Query: 102 FECSGIVEALGDSV-----KGYEIGDRVMAFV---NYNAWAEV-VCTPVEFVYKIPDDMS 152
           FE +G++EALG  +     +G  IG RV+ +        +AE+ V + ++ +  IPD + 
Sbjct: 2   FEVAGVIEALGSEITEANNRGLHIGQRVIVYPFDETPAGYAELLVVSDLKDIVPIPDSLP 181

Query: 153 FSEAAAFP------MNFVT-AYTMLFEIANLR 177
            +EAA  P      MN V  A  ++ +I N R
Sbjct: 182 MAEAAMLPTGALLAMNAVIKAQAVVTQILNQR 277
>21879
          Length = 353

 Score = 30.0 bits (66), Expect = 2.0,   Method: Composition-based stats.
 Identities = 10/33 (30%), Positives = 19/33 (57%)
 Frame = +2

Query: 117 GYEIGDRVMAFVNYNAWAEVVCTPVEFVYKIPD 149
           G  +G  +   ++   W E+ C P++FV++ PD
Sbjct: 194 GPTVGQSLTWLMSQRCWGELSC*PLQFVFRDPD 292
>21872
          Length = 405

 Score = 28.1 bits (61), Expect = 6.1,   Method: Composition-based stats.
 Identities = 14/45 (31%), Positives = 24/45 (53%)
 Frame = -3

Query: 140 PVEFVYKIPDDMSFSEAAAFPMNFVTAYTMLFEIANLREGMSVLV 184
           P +F +K+PDD++  E A      V  YT     A++  G ++L+
Sbjct: 289 PADFCFKLPDDVTMEEGAMMEPLAVAIYTC--RRADVTSGSNLLI 161
>09000
          Length = 1424

 Score = 28.1 bits (61), Expect = 6.7,   Method: Compositional matrix adjust.
 Identities = 16/42 (38%), Positives = 21/42 (50%), Gaps = 4/42 (9%)
 Frame = -1

Query: 256  NTGK----GLSLLKPLGTYILYGSSNMVTGETKSFFSFAKSW 293
            NT K    GL   K +  YI++ SS   TG+ K+F    K W
Sbjct: 1415 NTNKCYILGLVHKKEIHLYIIHNSSK*TTGQIKTFVKNPKKW 1290
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6755162|ref|NP_036001.1| protein kinase, interferon
inducible double stranded RNA dependent activator [Mus musculus]
         (313 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

05371                                                                 123   8e-29
23815                                                                  79   3e-15
17540                                                                  58   4e-09
09764                                                                  44   1e-04
04944                                                                  39   0.004
02302                                                                  32   0.31 
26504                                                                  30   1.5  
>05371
          Length = 1247

 Score =  123 bits (309), Expect = 8e-29,   Method: Compositional matrix adjust.
 Identities = 97/314 (30%), Positives = 153/314 (48%), Gaps = 34/314 (10%)
 Frame = +2

Query: 33  KTPIQVLHEYGMKTKNIPVYECERSDVQVHVPTFTFRVTVGDITCTGEGTSKKLAKHRAA 92
           KTPI  L EY  K    P Y+    +  VH PTF  +VTV + +  G+GTSKK AKH AA
Sbjct: 2   KTPISYLQEYCTKRNLTPDYQLLSHEGSVHEPTFLMKVTVAENSAEGKGTSKKKAKHSAA 181

Query: 93  EAAINILKANASICFAVPDPLMPDPSKQPKNQLNPIGSLQELAIHHGWRLPEYTLS--QE 150
            A +  +    +   A  +       +      NP+G LQEL+  H  + P YT +  Q 
Sbjct: 182 RAVLATILGVQNGQLAETEGGDEGGKEGVVAG-NPVGQLQELSQKHVMKPPLYTFTADQA 358

Query: 151 GGPAHKREYTTICRLESFMETGKGASKKQAKRNAAEKFLAKFS-----------NISPEN 199
               H R++    +L    E G+G SK+ +KR AA   L + +           NI  +N
Sbjct: 359 QPKPHDRKFYCTVKLGKLTENGEGPSKRASKRAAAAALLEQINKMAGAGGDHLLNIKSDN 538

Query: 200 HIS---------------------LTNVVGHSLGCTWHSLRNSPGEKINLLKRSLLSLPN 238
                                   LT      L   + ++  + G++   LK + ++ P 
Sbjct: 539 DTDDEIPVTKDSFMKKKKKSPAPLLTPQQSQELQLFYENMMKACGKQ---LKSAGVAAPA 709

Query: 239 TDYIQLLSEIASEQGFNITYLDIEELSANGQYQCLAELSTSPITVCHGSGISCGNAQSDA 298
            +Y Q+L EIA  + F++   ++EEL+  G +Q + +++T+PITVCHG G S  ++++ A
Sbjct: 710 ANYCQMLQEIADARHFDVALFELEELTTAGHFQAILKMTTNPITVCHGCGSSKEDSRASA 889

Query: 299 AHNALQYLKIIAER 312
           A+NALQYL+I+ ++
Sbjct: 890 AYNALQYLRILTKQ 931
>23815
          Length = 545

 Score = 78.6 bits (192), Expect = 3e-15,   Method: Compositional matrix adjust.
 Identities = 34/84 (40%), Positives = 60/84 (71%)
 Frame = +2

Query: 229 LKRSLLSLPNTDYIQLLSEIASEQGFNITYLDIEELSANGQYQCLAELSTSPITVCHGSG 288
           LK + ++ P  +Y Q+L EIA  + F++   ++EEL+  G +Q + +++T+PITVCHG G
Sbjct: 59  LKSAGVAAPAANYCQMLQEIADARHFDVALFELEELTTAGHFQAILKMTTNPITVCHGCG 238

Query: 289 ISCGNAQSDAAHNALQYLKIIAER 312
            S  ++++ AA+NALQYL+I+ ++
Sbjct: 239 SSKEDSRASAAYNALQYLRILTKQ 310
>17540
          Length = 1263

 Score = 58.2 bits (139), Expect = 4e-09,   Method: Compositional matrix adjust.
 Identities = 25/44 (56%), Positives = 36/44 (81%)
 Frame = +1

Query: 268 GQYQCLAELSTSPITVCHGSGISCGNAQSDAAHNALQYLKIIAE 311
           G YQ L +LST+P+ VCHGSG S  +++++AAHNALQYL+I+ +
Sbjct: 1   GPYQTLVKLSTNPVAVCHGSGSSKDDSRANAAHNALQYLRIMTK 132
>09764
          Length = 427

 Score = 43.5 bits (101), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 19/43 (44%), Positives = 30/43 (69%)
 Frame = -1

Query: 270 YQCLAELSTSPITVCHGSGISCGNAQSDAAHNALQYLKIIAER 312
           +Q +  L+T+  TVCHG G   G  ++ AA+NALQYL+I+ ++
Sbjct: 427 FQAI*RLTTTLSTVCHGXGSXQGRLRASAAYNALQYLRILTKQ 299
>04944
          Length = 863

 Score = 38.5 bits (88), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 31/120 (25%), Positives = 54/120 (45%), Gaps = 4/120 (3%)
 Frame = +2

Query: 66  FTFRVTVGDITCTGEGTSKKLAKHRAAEAAINILKANASICFAVPDPLMPDPSKQPKNQL 125
           F   + VG     G+G +++ A+H AA  A+ ILK         P      P+++ +   
Sbjct: 440 FYVMLKVGPKEFIGDGPTRQAARHNAATKALKILK-----ILPTPADAGKTPAEEEEESE 604

Query: 126 NPIGS----LQELAIHHGWRLPEYTLSQEGGPAHKREYTTICRLESFMETGKGASKKQAK 181
           N I S    + E+A+     +  + + +E GP H + + T C +       +G SKK +K
Sbjct: 605 NGIKSEISLVHEMALKRNLPV-AFEVVRESGPPHMKNFVTKCVVGELTTEAEGNSKKLSK 781

 Score = 26.9 bits (58), Expect = 9.4,   Method: Compositional matrix adjust.
 Identities = 20/56 (35%), Positives = 27/56 (48%), Gaps = 2/56 (3%)
 Frame = +3

Query: 144 EYTLSQEGGPAHKREYTTICRL--ESFMETGKGASKKQAKRNAAEKFLAKFSNISP 197
           +YTL  E GPAHK+ +    +L  E + E G+   K Q    A      KFS+  P
Sbjct: 78  QYTLVDEQGPAHKKTFYVKLKLGEEEYSEQGESIKKAQHAAAAIALTETKFSHPPP 245
>02302
          Length = 1179

 Score = 32.0 bits (71), Expect = 0.31,   Method: Compositional matrix adjust.
 Identities = 16/36 (44%), Positives = 20/36 (55%)
 Frame = -3

Query: 61  VHVPTFTFRVTVGDITCTGEGTSKKLAKHRAAEAAI 96
           VH P FT  V V      G G +K+ AK  AAE+A+
Sbjct: 370 VHSPVFTMSVDVNGENFRGNGPTKRKAKMAAAESAL 263

 Score = 28.1 bits (61), Expect = 4.9,   Method: Compositional matrix adjust.
 Identities = 15/49 (30%), Positives = 22/49 (44%)
 Frame = -3

Query: 144 EYTLSQEGGPAHKREYTTICRLESFMETGKGASKKQAKRNAAEKFLAKF 192
           E+    + GP H   +T    +      G G +K++AK  AAE  L  F
Sbjct: 400 EFRFESQSGPVHSPVFTMSVDVNGENFRGNGPTKRKAKMAAAESALRSF 254
>26504
          Length = 1313

 Score = 29.6 bits (65), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 17/46 (36%), Positives = 23/46 (50%), Gaps = 1/46 (2%)
 Frame = +1

Query: 201 ISLTNVVGHSLGCTWHSLRNSP-GEKINLLKRSLLSLPNTDYIQLL 245
           + + N++ H L C    L  S   EKI L K+ L  L  TDY + L
Sbjct: 460 VDIRNMIQHVLTCRKDKLNKSRLVEKIQLRKKMLKYLRRTDYQRFL 597
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|113930735|ref|NP_032832.2| rod cGMP-phosphodiesterase
beta-subunit [Mus musculus]
         (856 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

28167                                                                 124   1e-28
13617                                                                  51   2e-06
16955                                                                  35   0.11 
16973                                                                  33   0.48 
34566                                                                  30   3.3  
13996                                                                  30   5.6  
>28167
          Length = 587

 Score =  124 bits (312), Expect = 1e-28,   Method: Compositional matrix adjust.
 Identities = 67/148 (45%), Positives = 95/148 (64%)
 Frame = +2

Query: 665 IATDLALYFKKRTMFQKIVDESKNYEDKKSWVEYLSLETTRKEIVMAMMMTACDLSAITK 724
           +ATDLALYF+ R  F    D +K+ E   +W +  +     ++++ +MMMTA D++AITK
Sbjct: 2   LATDLALYFRYRGRF---FDLTKSPE--VNWSDDCN-----RDLLRSMMMTASDVAAITK 151

Query: 725 PWEVQSKVALLVAAEFWEQGDLERTVLDQQPIPMMDRNKAAELPKLQVGFIDFVCTFVYK 784
           PWEVQ KVA LV+ EF+EQGD+E+  L  QP+ MMDR K  +LP +QVGFID +C  VY+
Sbjct: 152 PWEVQKKVAHLVSREFFEQGDMEKETLKIQPMEMMDREKKDKLPNMQVGFIDTICLPVYE 331

Query: 785 EFSRFHEEILPMFDRLQNNRKEWKALAD 812
             +R    + P+    Q NR  W + A+
Sbjct: 332 AMTRVSPRLSPLLKGCQQNRDHWMSEAE 415
>13617
          Length = 465

 Score = 50.8 bits (120), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 25/86 (29%), Positives = 44/86 (51%)
 Frame = +2

Query: 381 KNVLSMPIVNKKEEIVGVATFYNRKDGKPFDDQDEVLMESLTQFLGWSVLNTDTYDKMNK 440
           K +L MPI N   +++GV    N+ D   F+  DE L E+   F G  + NT  Y+   K
Sbjct: 80  KCILCMPIKNVAGKVIGVMQLINKLDNTAFNKNDENLFEAFAIFCGMGINNTSMYETAMK 259

Query: 441 LENRKDIAQDMVLYHVRCDKDEIQEI 466
              ++ +A +++ YH     +E +++
Sbjct: 260 AIAKQRVALEVMSYHAMAPMEEAEKL 337
>16955
          Length = 862

 Score = 35.0 bits (79), Expect = 0.11,   Method: Composition-based stats.
 Identities = 13/24 (54%), Positives = 19/24 (79%)
 Frame = +1

Query: 781 FVYKEFSRFHEEILPMFDRLQNNR 804
           F+ +EFSRFH++I P+  R Q+NR
Sbjct: 640 FILREFSRFHKQITPLIVRHQSNR 711
>16973
          Length = 1511

 Score = 33.1 bits (74), Expect = 0.48,   Method: Compositional matrix adjust.
 Identities = 13/25 (52%), Positives = 19/25 (76%)
 Frame = +2

Query: 780  TFVYKEFSRFHEEILPMFDRLQNNR 804
             F+ +EFSRFH++I P+  R Q+NR
Sbjct: 1067 NFILREFSRFHKQITPLIVRHQSNR 1141
>34566
          Length = 481

 Score = 30.4 bits (67), Expect = 3.3,   Method: Composition-based stats.
 Identities = 24/81 (29%), Positives = 35/81 (43%), Gaps = 6/81 (7%)
 Frame = -3

Query: 222 IYHLSYLHNCETRRGQVLLWSANKVFEELTDIERQFHKAFYTV------RAYLNCERYSV 275
           I+ LSY H  E   G    +S NKV  E   I   F+  F  +       A   C++  +
Sbjct: 365 IFCLSYQHEVEGFSGSCHYFSKNKV*AE--SIINTFNIIFVILMQMDWFEALFTCQKLKL 192

Query: 276 GLLDMTKEKEFFDVWPVLMGE 296
            L +M  ++ F D+   L GE
Sbjct: 191 CLANMDSKRSFEDIGKKLTGE 129
>13996
          Length = 515

 Score = 29.6 bits (65), Expect = 5.6,   Method: Composition-based stats.
 Identities = 11/23 (47%), Positives = 17/23 (73%)
 Frame = +1

Query: 762 NKAAELPKLQVGFIDFVCTFVYK 784
           ++  +LP +QVGFID +C  VY+
Sbjct: 325 SRRTKLPTMQVGFIDSICLPVYE 393
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|148539957|ref|NP_666212.3| internexin neuronal
intermediate filament protein, alpha [Mus musculus]
         (501 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

11243                                                                 124   1e-28
02016                                                                  86   4e-17
22014                                                                  49   7e-06
26996                                                                  36   0.029
28040                                                                  30   2.0  
13635                                                                  29   5.6  
>11243
          Length = 828

 Score =  124 bits (310), Expect = 1e-28,   Method: Compositional matrix adjust.
 Identities = 79/211 (37%), Positives = 124/211 (58%), Gaps = 3/211 (1%)
 Frame = -2

Query: 201 RDVDGATLARLDLEKKVESLLDELAFVRQVHDEEVXXXXXXXXXXXXXXXXVDVAV--AK 258
           R +D  TL + DLE ++ESL +EL ++++ H+EE+                VDV V  A 
Sbjct: 800 RVLDELTLNKTDLELEIESLKEELIYLKKNHEEELAVVRSSARGN------VDVQVDSAP 639

Query: 259 P-DLTSALREIRAQYESLAAKNLQSAEEWYKSKFANLNEQAARSTEAIRASREEIHEYRR 317
           P DL   + ++R+QYES+  KN Q  E  YK +  NLN + A +T A++ S+  I + +R
Sbjct: 638 PVDLAQIMXDVRSQYESMMEKNRQELEACYKGQSENLNHEVATNTAALQTSKTAITDLKR 459

Query: 318 QLQARTIEIEGLRGANESLERQILELEERHSAEVAGYQDSIGQLESDLRNTKSEMARHLR 377
            +Q+  IE++ L     +LE  + E E ++ A++   Q  I Q+E +L+N +S+      
Sbjct: 458 TIQSLEIELQSLLSMKGALEGTLAETEAQYGAQLNHLQAMITQVEMELQNLRSDADHQSL 279

Query: 378 EYQDLLNVKMALDIEIAAYRKLLEGEETRFS 408
           EY+ LL+ K  L++EIA YR+LLEGE+TRFS
Sbjct: 278 EYKRLLDAKTRLEMEIATYRRLLEGEDTRFS 186
>02016
          Length = 3061

 Score = 85.9 bits (211), Expect = 4e-17,   Method: Compositional matrix adjust.
 Identities = 68/206 (33%), Positives = 110/206 (53%), Gaps = 4/206 (1%)
 Frame = +3

Query: 207 TLARLDLEKKVESLLDELAFVRQVHDEEVXXXXXXXXXXXXXXXXVDVAVAKPDLTSALR 266
           TL R+DLE +++SL +E+ F  QV+++E+                      +  L  ALR
Sbjct: 183 TLLRVDLENRLQSLKEEINFKSQVYEQELEESRVRTTVEIEQVDGRLEHEYEQRLLEALR 362

Query: 267 EIRAQYESLAAKNLQSA----EEWYKSKFANLNEQAARSTEAIRASREEIHEYRRQLQAR 322
           EIRAQ+ES    +LQ+     E  Y++K A+L  QA RS  A  ++ EE+   R++    
Sbjct: 363 EIRAQHES----DLQTVRVELETLYENKIADLKAQANRSNSASGSAWEELRITRKRADDL 530

Query: 323 TIEIEGLRGANESLERQILELEERHSAEVAGYQDSIGQLESDLRNTKSEMARHLREYQDL 382
             E+  L+      E +I +LE + + E   ++  + Q + +L   +  +   ++EY DL
Sbjct: 531 GAELAKLKAETAGFELRISDLESQLAREREEFRLRLAQKDDELAELRLTLEEQMQEYSDL 710

Query: 383 LNVKMALDIEIAAYRKLLEGEETRFS 408
           L++K+ LD EI AYRKLLE EE+R +
Sbjct: 711 LDIKIRLDREIDAYRKLLESEESRLN 788
>22014
          Length = 353

 Score = 48.5 bits (114), Expect = 7e-06,   Method: Compositional matrix adjust.
 Identities = 23/49 (46%), Positives = 36/49 (73%)
 Frame = -1

Query: 358 IGQLESDLRNTKSEMARHLREYQDLLNVKMALDIEIAAYRKLLEGEETR 406
           + QL+ ++   ++EM   L E Q L++ K++L++EIAAYRKLLE EE+R
Sbjct: 212 VNQLKEEMNKLRAEMEAMLVELQTLMDAKLSLELEIAAYRKLLETEESR 66
>26996
          Length = 386

 Score = 36.2 bits (82), Expect = 0.029,   Method: Compositional matrix adjust.
 Identities = 16/29 (55%), Positives = 21/29 (72%)
 Frame = -1

Query: 91  RTNEKEQLQGLNDRFAVFIEKVHQLETQN 119
           R  E+E LQGLNDR A +I++V  LE +N
Sbjct: 233 RQQEQESLQGLNDRLANYIDRVRFLEAEN 147
>28040
          Length = 433

 Score = 30.0 bits (66), Expect = 2.0,   Method: Compositional matrix adjust.
 Identities = 23/63 (36%), Positives = 33/63 (52%)
 Frame = +3

Query: 319 LQARTIEIEGLRGANESLERQILELEERHSAEVAGYQDSIGQLESDLRNTKSEMARHLRE 378
           L AR  E+E L    E L+ ++ E EE    EV G Q S+G L+  +  TKS++     +
Sbjct: 72  LSARDSELEQLMSQTEQLKEKLSEREE----EVTGLQASLGSLQDVIAMTKSDLEAVTED 239

Query: 379 YQD 381
           Y D
Sbjct: 240 YND 248
>13635
          Length = 1015

 Score = 28.9 bits (63), Expect = 5.6,   Method: Compositional matrix adjust.
 Identities = 20/52 (38%), Positives = 30/52 (57%), Gaps = 3/52 (5%)
 Frame = +1

Query: 294 LNEQAARSTEAIRASRE---EIHEYRRQLQARTIEIEGLRGANESLERQILE 342
           L EQA  STE  R  ++   +    +R+LQA  +E++GLR  N+  +R I E
Sbjct: 388 LEEQAEASTELQRQYKDKHRDCEMTKRELQAAQLEVKGLREQNDYKDRLISE 543
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|158081796|ref|NP_034491.2| glutathione S-transferase,
theta 2 [Mus musculus]
         (244 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

20209                                                                 122   1e-28
08076                                                                  75   3e-14
20405                                                                  47   1e-05
18203                                                                  39   0.002
02955                                                                  28   2.9  
>20209
          Length = 979

 Score =  122 bits (306), Expect = 1e-28,   Method: Compositional matrix adjust.
 Identities = 71/186 (38%), Positives = 108/186 (58%), Gaps = 2/186 (1%)
 Frame = -1

Query: 33  VDILKGQHMSEQFSQVNCLNKVPVLKDGSFVLTESTAILIYLSSKYQVADHWYPADLQAR 92
           V + KG+H SE F +V+    VP L D  F LTES AI+ Y++    VADHW PAD + R
Sbjct: 976 VALRKGEHYSEDFVKVHPFRLVPALNDDGFRLTESIAIVDYIAKTRDVADHWLPADPKKR 797

Query: 93  AQVHEYLGWHADNIRGTFGVLLWTKVLGP-LIGVQVPQEKVERNRDRMVLVLQQLEDKFL 151
           A+V+EYL WH  N R +  +L    +L P + G  V Q++V+    R+   ++ +E+ FL
Sbjct: 796 AKVNEYLHWHHANTRLSSAMLFQHLLLIPRMKGEPVDQKQVKTFTKRVQTAIKGIENYFL 617

Query: 152 RDRAFLVGQQVTLADLMSLEELMQPVALGY-NLFEGRPQLTAWRERVEAFLGAELCQEAH 210
           +D  F+    +T+AD+ ++ ELMQ  A+    L+E  P + AW ERV+  +G  L  +AH
Sbjct: 616 KDTPFISSDVITVADIFAVCELMQLYAVRQEELYESSPVVKAWVERVKKEIGP-LFDKAH 440

Query: 211 STILSI 216
             +  +
Sbjct: 439 QVVYRV 422
>08076
          Length = 914

 Score = 75.1 bits (183), Expect = 3e-14,   Method: Compositional matrix adjust.
 Identities = 46/133 (34%), Positives = 75/133 (56%), Gaps = 2/133 (1%)
 Frame = -2

Query: 86  PADLQARAQVHEYLGWHADNIRGTFGVLLWTKVLGP-LIGVQVPQEKVERNRDRMVLVLQ 144
           PAD + RA+V EYL WH  N R +  +L    +L P + G  V Q++V+    R+   ++
Sbjct: 910 PADPKKRAKVDEYLHWHHANTRLSSAMLFQHLLLIPRMKGEPVDQKQVKTFTKRVQTAIK 731

Query: 145 QLEDKFLRDRAFLVGQQVTLADLMSLEELMQPVALGY-NLFEGRPQLTAWRERVEAFLGA 203
            +E+ FL+D  F+    +T+AD+ ++ ELMQ  A+    L+E  P + AW ERV+  +G 
Sbjct: 730 GIENYFLKDTPFISSNVITVADIFAVCELMQLYAVRQEELYESSPVVKAWVERVKKEIGP 551

Query: 204 ELCQEAHSTILSI 216
            L  +AH  +  +
Sbjct: 550 -LFDKAHQVVYRV 515
>20405
          Length = 766

 Score = 46.6 bits (109), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 40/160 (25%), Positives = 76/160 (47%), Gaps = 3/160 (1%)
 Frame = -1

Query: 19  IFAKKNGIPFQTRTVDILKGQHMSEQFSQVNCLNKVPVLK--DGSFVLTESTAILIYLSS 76
           I AK +G   +     +    + S+ F +     KVP  +  DG  +LTES AI  Y+++
Sbjct: 721 IAAKYSGADVKVAPNFVFGETNKSDGFLKKFPAGKVPAYESADGKVLLTESNAIAYYVAN 542

Query: 77  KYQVADHWYPADLQARAQVHEYLGWHADNIRGTFGVLLWTKVLGPLIGV-QVPQEKVERN 135
                     +D+  +A ++++  W    +       ++     P +G+ Q  ++ VER 
Sbjct: 541 ATLRG-----SDVATQAAIYQWASWADSELLPASCAWVF-----PYLGIMQFNKQNVERA 392

Query: 136 RDRMVLVLQQLEDKFLRDRAFLVGQQVTLADLMSLEELMQ 175
           ++ ++  L+ L D  L  R FLV +++TLAD++    L+ 
Sbjct: 391 KNDLLAALKVL-DGHLLTRTFLVTERITLADIIVFTTLIH 275
>18203
          Length = 435

 Score = 38.5 bits (88), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 24/75 (32%), Positives = 38/75 (50%), Gaps = 1/75 (1%)
 Frame = +2

Query: 3   LELYLDLLSQPSRAVYIFAKKNGIPFQTRTVDILKGQHMSEQFSQVNCLNK-VPVLKDGS 61
           + LY    S  S+ V + A + G+ F+ R V +  GQHM   + ++N     VPVL  G+
Sbjct: 110 ITLYYFPTSFSSQKVLLAAYEKGVQFKPRLVSLFHGQHMEPWYVKLNPEGTHVPVLVHGA 289

Query: 62  FVLTESTAILIYLSS 76
            +L     I+ Y+ S
Sbjct: 290 LILNNPEEIIDYIDS 334
>02955
          Length = 1322

 Score = 28.5 bits (62), Expect = 2.9,   Method: Compositional matrix adjust.
 Identities = 20/58 (34%), Positives = 30/58 (51%), Gaps = 6/58 (10%)
 Frame = +1

Query: 126 QVPQEKVERNRDRMVLVLQQLEDKFLR------DRAFLVGQQVTLADLMSLEELMQPV 177
           Q PQ+K ER R+   +   +    F R      D+ + VG  VTLADL  L ++++ V
Sbjct: 352 QDPQKKAERTRELTEVQYPRYLSSFERLLAENGDQGYSVGDSVTLADL-CLHDVLETV 522
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|19526900|ref|NP_598479.1| transmembrane protein 30A
[Mus musculus]
         (364 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

27743                                                                 123   1e-28
23347                                                                  28   4.5  
>27743
          Length = 491

 Score =  123 bits (309), Expect = 1e-28,   Method: Compositional matrix adjust.
 Identities = 62/135 (45%), Positives = 81/135 (60%), Gaps = 7/135 (5%)
 Frame = -1

Query: 34  KQQRLPAWQPILTAGTVLPTXXXXXXXXXXXXXXXXVTSNNIREIEIDYTG-TEPSSPCN 92
           KQQ+LPAWQPILTA TVLP                 +TSNNI+E+  DYT  T  ++   
Sbjct: 407 KQQKLPAWQPILTANTVLPAFFAIGLAFIPLGVALLLTSNNIKEVVYDYTHCTNVANQSQ 228

Query: 93  KCL------SPNVTSCACTINFTLKQSFEGNVFMYYGLSNFYQNHRRYVKSRDDSQLNGD 146
            C       +     C C +N TL++ F G V+MYY L+NFYQNHRRYV+SRDD QL+GD
Sbjct: 227 TCAEFFQETNKTFQICTCVVNITLEEDFTGTVYMYYALTNFYQNHRRYVRSRDDDQLHGD 48

Query: 147 PSALLNPSKECEPYR 161
             +  +  ++C+PYR
Sbjct: 47  VMSSGDLHEDCDPYR 3
>23347
          Length = 1550

 Score = 28.5 bits (62), Expect = 4.5,   Method: Compositional matrix adjust.
 Identities = 13/41 (31%), Positives = 20/41 (48%)
 Frame = -1

Query: 288  TLPAGQYFLNITYNYPVHSFDGRKRMILSTISWMGGKNPFL 328
             LP      NIT++Y +     +  M++   SW+  K PFL
Sbjct: 1325 ILPDAVQI*NITFSYLMLLQQNKPVMLIDICSWLESKRPFL 1203
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31981310|ref|NP_036190.2| B-cell receptor-associated
protein 31 [Mus musculus]
         (245 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

20924                                                                 122   1e-28
28914                                                                  39   0.003
>20924
          Length = 689

 Score =  122 bits (307), Expect = 1e-28,   Method: Compositional matrix adjust.
 Identities = 66/175 (37%), Positives = 94/175 (53%), Gaps = 1/175 (0%)
 Frame = -2

Query: 1   MSLQWTTVATFLYAEVFAVLLLCIPFISPKRWQKVFKSRLVELVVTYGNTFFXXXXXXXX 60
           M+LQWT VA  +Y EV  + LL +PFISP RWQK+F+SR++  + +Y N +F        
Sbjct: 547 MTLQWTFVAACMYTEVCVITLLLLPFISPSRWQKIFRSRILAGLKSYANLYFNVFIAVLL 368

Query: 61  XXXXDAVREILKYDDVTEKVNLQNNPGAMEHFHMKLFRAQRNLYIAGXXXXXXXXXXXXV 120
               +++RE+ KY +  E  +L+++P A   +HMKLFRAQRNLYIAG            V
Sbjct: 367 LLFFESIREVRKYSEPIEVEDLKHHPEAETLYHMKLFRAQRNLYIAGFALFLWFVVRRLV 188

Query: 121 TLISQQATLLASNXXXXXXXXXXXXXXXXXXXXNDQLKKGAAEDG-DKLDIGNTE 174
            LI+ +ATLLA +                     D  K  + E+G DK D G ++
Sbjct: 187 VLIASEATLLAESTAAKRQAESATAAAQQLLDQQDNSKNVSKEEGKDKGDKGESK 23
>28914
          Length = 429

 Score = 38.5 bits (88), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 16/23 (69%), Positives = 22/23 (95%)
 Frame = -3

Query: 211 MQKQSEGLTKEYDRLLEEHAKLQ 233
           M+KQ+E +T+EYDRLL+EH+KLQ
Sbjct: 373 MKKQAESVTQEYDRLLDEHSKLQ 305
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|61098173|ref|NP_848801.2| centrosomal protein 120
[Mus musculus]
         (988 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

18616                                                                 125   1e-28
19276                                                                  57   2e-14
>18616
          Length = 451

 Score =  125 bits (313), Expect = 1e-28,   Method: Compositional matrix adjust.
 Identities = 59/106 (55%), Positives = 76/106 (71%), Gaps = 1/106 (0%)
 Frame = +3

Query: 505 EVFLPQSYCAFDFATMPHQLQDTFLRIPLLVELWHKDK-MSKDLLLGVARIQLSNILSSE 563
           EV LPQS+CAFDFA    QLQDTF R+ L VE+W +DK +SKD+LLG AR+ LS+ L+++
Sbjct: 6   EVLLPQSFCAFDFACTMQQLQDTFRRVSLTVEVWQRDKQLSKDVLLGTARLPLSHCLTAQ 185

Query: 564 KTRFLGANGEQCWRQTYSESVPVIAAQGSNNRILDLSYTMTLEDYG 609
           K R +GAN    WRQ YS+ VPV A +G   +  D+S  MTLED+G
Sbjct: 186 KMRTMGANNTPGWRQEYSDRVPVTAVEGPIQQCADISLVMTLEDWG 323
>19276
          Length = 460

 Score = 57.0 bits (136), Expect(2) = 2e-14,   Method: Compositional matrix adjust.
 Identities = 28/62 (45%), Positives = 40/62 (64%)
 Frame = -2

Query: 295 STEINQHPVTVEGAFTLDPPNRAKQKLAPVPLDLAPTVGVSVALQREGIDSQSLIELKTQ 354
           STEI   PV+VEG F L PPN+ KQ++  VP  L+P VGVSV L++E + + + ++    
Sbjct: 393 STEIYMKPVSVEGDFQLVPPNKVKQQIPAVPTSLSPVVGVSVVLRKEDMGAVTPVKDHAN 214

Query: 355 NG 356
           N 
Sbjct: 213 NA 208

 Score = 41.2 bits (95), Expect(2) = 2e-14,   Method: Composition-based stats.
 Identities = 17/21 (80%), Positives = 18/21 (85%)
 Frame = -3

Query: 273 LCCGDQSLGSTEIPLNGLLKK 293
           LCCGDQSLGS E+PL  LLKK
Sbjct: 458 LCCGDQSLGSCEVPLKSLLKK 396
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6678329|ref|NP_033399.1| transglutaminase 2, C
polypeptide [Mus musculus]
         (686 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

19839                                                                 124   1e-28
29403                                                                  75   1e-18
24318                                                                  55   9e-08
31648                                                                  50   2e-06
06532                                                                  34   0.18 
38864                                                                  32   0.84 
14090                                                                  31   1.6  
21430                                                                  29   7.0  
>19839
          Length = 438

 Score =  124 bits (311), Expect = 1e-28,   Method: Compositional matrix adjust.
 Identities = 63/146 (43%), Positives = 90/146 (61%), Gaps = 3/146 (2%)
 Frame = +2

Query: 248 GISPMAWIGSVDILRRWKEHGCQQVKYGQCWVFAAVACTVLRCLGIPTRVVTNYNSAHDQ 307
           G  P  WI S  IL  ++E   + VKYGQCWVF+ +  TV R LG+P R VT ++SAHD 
Sbjct: 2   GTKPTDWISSQKILEEYEETK-EPVKYGQCWVFSHLLTTVCRALGLPCRSVTCFDSAHDT 178

Query: 308 NSNLLIEYFRNEFGELESN-KSEMIWNFHCWVESWMTRPDLQP--GYEGWQAIDPTPQEK 364
           +++  I+ + NE G+ +    S+ IWNFH W E W+ RP  +    + GW  ID TPQE+
Sbjct: 179 DNSCTIDNYYNEDGDKDDRMTSDSIWNFHVWNEVWLMRPVFKEMGDFSGWHVIDATPQEQ 358

Query: 365 SEGTYCCGPVSVRAIKEGDLSTKYDA 390
           S G++ CG V  +AIK+G ++  +D 
Sbjct: 359 SYGSFQCGLVL*KAIKDGHITVGFDT 436
>29403
          Length = 362

 Score = 75.5 bits (184), Expect(3) = 1e-18,   Method: Compositional matrix adjust.
 Identities = 35/75 (46%), Positives = 53/75 (70%)
 Frame = +3

Query: 248 GISPMAWIGSVDILRRWKEHGCQQVKYGQCWVFAAVACTVLRCLGIPTRVVTNYNSAHDQ 307
           G +P  W GS  IL++++E G + V++GQCWVF+ +  TV R LG+P R VT ++SAHD 
Sbjct: 6   GTNPCDWQGSRKILKQYEESG-KPVQFGQCWVFSHLLTTVCRALGLPCRSVTCFDSAHDT 182

Query: 308 NSNLLIEYFRNEFGE 322
           ++N +I YF +E G+
Sbjct: 183 DNNCVINYFYDEDGK 227

 Score = 28.5 bits (62), Expect(3) = 1e-18,   Method: Composition-based stats.
 Identities = 9/15 (60%), Positives = 11/15 (73%)
 Frame = +1

Query: 328 SEMIWNFHCWVESWM 342
           S+ IWNFH W E W+
Sbjct: 247 SDSIWNFHVWNELWI 291

 Score = 27.7 bits (60), Expect(3) = 1e-18,   Method: Composition-based stats.
 Identities = 12/21 (57%), Positives = 13/21 (61%), Gaps = 2/21 (9%)
 Frame = +2

Query: 345 PDLQPG--YEGWQAIDPTPQE 363
           PDL     Y+GW  ID TPQE
Sbjct: 299 PDLDDAGDYDGWHVIDATPQE 361
>24318
          Length = 819

 Score = 55.1 bits (131), Expect = 9e-08,   Method: Compositional matrix adjust.
 Identities = 50/205 (24%), Positives = 77/205 (37%), Gaps = 1/205 (0%)
 Frame = +3

Query: 480 GDSMSMGNDFDVFAHIGNDTSETRECRLLLCARTVSYNGVLGPECGTEDI-NLTLDPYSE 538
            D+  +G DF     + N + E R     L A TV Y GV G     E I  + L P   
Sbjct: 45  ADNSYVGQDFVTELRMKNTSKEHRCIFGQLSANTVYYTGVFGENVAKEIIAGVMLKPGES 224

Query: 539 NSIPLRILYEKYSGCLTESNLIKVRGLLIEPAANSYLLAERDLYLENPEIKIRVLGEPKQ 598
             I +R+  E Y   L +  ++ +  +            + D  L  P + I+     K 
Sbjct: 225 KVIEIRVKPEDYHKKLKDCCMLSMSAMARVVDTKQIYTVKDDARLRKPHLNIKAPKTGKV 404

Query: 599 NRKLVAEVSLKNPLSDPLYDCIFTVEGAGLTKEQKSVEVSDPVPAGDLVKARVDLFPTDI 658
            ++   EVS  N L     DC   VEG     + K  +  D    G  +   + L P+  
Sbjct: 405 GQEFEVEVSFTNCLPQTXTDCTLEVEGTPGLPKAKIFDQGDVQGKGTFL-TTIKLKPSKK 581

Query: 659 GLHKLVVNFQCDKLKSVKGYRNVII 683
           G   +V  F   +L+ + G   + I
Sbjct: 582 GKRDIVFIFSSKQLEDINGSHEIDI 656
>31648
          Length = 422

 Score = 50.4 bits (119), Expect = 2e-06,   Method: Composition-based stats.
 Identities = 29/114 (25%), Positives = 52/114 (45%), Gaps = 5/114 (4%)
 Frame = -2

Query: 11  DLEIQANGRDHHTADL-----CQEKLVLRRGQRFRLTLYFEGRGYEASVDSLTFGAVTGP 65
           D ++  N + HHT +         +LV+RRGQ F + + F  R   A  D        G 
Sbjct: 340 DYQVALNTKQHHTDEFDITESSNPQLVVRRGQPFTIQIRFS-RTLVARTDDFRLIFEIGQ 164

Query: 66  DPSEEAGTKARFSLSDNVEEGSWSASVLDQQDNVLSLQLCTPANAPIGLYRLSL 119
           +P    GTK   + S N   G W A ++  +  +  +++ +P +  +G + +S+
Sbjct: 163 NPQASKGTKVVLNPSKNASSGKWGAQLVGVRGAIAEVKVVSPPDCIVGKWTVSV 2
>06532
          Length = 440

 Score = 34.3 bits (77), Expect = 0.18,   Method: Composition-based stats.
 Identities = 26/87 (29%), Positives = 37/87 (42%)
 Frame = +1

Query: 597 KQNRKLVAEVSLKNPLSDPLYDCIFTVEGAGLTKEQKSVEVSDPVPAGDLVKARVDLFPT 656
           K  ++   EVS  N L   L DC   VEG GL K  K  +  D    G  +   + L P+
Sbjct: 1   KVGQEFEVEVSFTNCLPQTLTDCTLEVEGPGLPK-AKIFDQGDVQGKGTFLTT-IKLKPS 174

Query: 657 DIGLHKLVVNFQCDKLKSVKGYRNVII 683
             G   +V  F   +L+ + G   + I
Sbjct: 175 KKGKRDIVFIFSSKQLEDINGSHEIDI 255
>38864
          Length = 391

 Score = 32.0 bits (71), Expect = 0.84,   Method: Composition-based stats.
 Identities = 11/14 (78%), Positives = 12/14 (85%)
 Frame = +2

Query: 437 EDITHTYKYPEGSP 450
           ED+ H YKYPEGSP
Sbjct: 32  EDVMHNYKYPEGSP 73
>14090
          Length = 411

 Score = 31.2 bits (69), Expect = 1.6,   Method: Composition-based stats.
 Identities = 11/21 (52%), Positives = 15/21 (71%)
 Frame = -3

Query: 436 REDITHTYKYPEGSPEEREVF 456
           +  +THTYK+P G P+E  VF
Sbjct: 388 KNTLTHTYKHPSGIPQEISVF 326
>21430
          Length = 552

 Score = 28.9 bits (63), Expect = 7.0,   Method: Composition-based stats.
 Identities = 11/25 (44%), Positives = 14/25 (56%)
 Frame = -1

Query: 264 WKEHGCQQVKYGQCWVFAAVACTVL 288
           W    CQ    G+CW+ AAVA  V+
Sbjct: 228 WX*SNCQDCSAGECWLLAAVALHVV 154
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|84000448|ref|NP_034407.2| glial fibrillary acidic
protein isoform 2 [Mus musculus]
         (430 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

11243                                                                 123   1e-28
02016                                                                 101   4e-22
22014                                                                  49   3e-06
19956                                                                  48   8e-06
26996                                                                  42   5e-04
11942                                                                  28   8.0  
>11243
          Length = 828

 Score =  123 bits (309), Expect = 1e-28,   Method: Compositional matrix adjust.
 Identities = 89/261 (34%), Positives = 151/261 (57%), Gaps = 4/261 (1%)
 Frame = -2

Query: 162 AENNLAAYRQEADEATLARVDLERKVESLEEEIQFLRKIYEEEVRELREQLAQQQVHVEM 221
           AE+++   R+  DE TL + DLE ++ESL+EE+ +L+K +EEE+  +R   A+  V V++
Sbjct: 827 AESDIVGLRRVLDELTLNKTDLELEIESLKEELIYLKKNHEEELAVVRSS-ARGNVDVQV 651

Query: 222 DVAKP-DLTAALREIRTQYEAVATSNMQETEEWYRSKFADLTDAASRNAELLRQAKHEAN 280
           D A P DL   + ++R+QYE++   N QE E  Y+ +  +L    + N   L+ +K    
Sbjct: 650 DSAPPVDLAQIMXDVRSQYESMMEKNRQELEACYKGQSENLNHEVATNTAALQTSKTAIT 471

Query: 281 DYRRQLQALTCDLESLRGTNESLERQMREQEERHARESASYQEALARLEEEGQSLKEEMA 340
           D +R +Q+L  +L+SL     +LE  + E E ++  +    Q  + ++E E Q+L+ +  
Sbjct: 470 DLKRTIQSLEIELQSLLSMKGALEGTLAETEAQYGAQLNHLQAMITQVEMELQNLRSDAD 291

Query: 341 RHLQEYQDLLNVKLALDIEIATYRKLLEGEENRITIPVQTFSNLQIRE-TSLDTKSVSEG 399
               EY+ LL+ K  L++EIATYR+LLEGE+ R       FS  + ++  ++ +K  S  
Sbjct: 290 HQSLEYKRLLDAKTRLEMEIATYRRLLEGEDTR-------FSQTETQKAVTIVSKEQSSS 132

Query: 400 HLKRNIVVKTV--EMRDGEVI 418
            +K+   VKTV  E+ DG+V+
Sbjct: 131 SIKK---VKTVIEEVVDGKVV 78
>02016
          Length = 3061

 Score =  101 bits (252), Expect = 4e-22,   Method: Compositional matrix adjust.
 Identities = 78/226 (34%), Positives = 122/226 (53%), Gaps = 10/226 (4%)
 Frame = +3

Query: 163 ENNLAAYRQEADEATLARVDLERKVESLEEEIQFLRKIYEEEVRELREQLAQQQVHVEMD 222
           E  LA  +++ +E TL RVDLE +++SL+EEI F  ++YE+E+ E R       V   ++
Sbjct: 141 EKQLAKLKKQLEEETLLRVDLENRLQSLKEEINFKSQVYEQELEESR-------VRTTVE 299

Query: 223 VAKPD----------LTAALREIRTQYEAVATSNMQETEEWYRSKFADLTDAASRNAELL 272
           + + D          L  ALREIR Q+E+   +   E E  Y +K ADL   A+R+    
Sbjct: 300 IEQVDGRLEHEYEQRLLEALREIRAQHESDLQTVRVELETLYENKIADLKAQANRSNSAS 479

Query: 273 RQAKHEANDYRRQLQALTCDLESLRGTNESLERQMREQEERHARESASYQEALARLEEEG 332
             A  E    R++   L  +L  L+      E ++ + E + ARE   ++  LA+ ++E 
Sbjct: 480 GSAWEELRITRKRADDLGAELAKLKAETAGFELRISDLESQLAREREEFRLRLAQKDDEL 659

Query: 333 QSLKEEMARHLQEYQDLLNVKLALDIEIATYRKLLEGEENRITIPV 378
             L+  +   +QEY DLL++K+ LD EI  YRKLLE EE+R+ I +
Sbjct: 660 AELRLTLEEQMQEYSDLLDIKIRLDREIDAYRKLLESEESRLNISL 797
>22014
          Length = 353

 Score = 49.3 bits (116), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 28/68 (41%), Positives = 41/68 (60%)
 Frame = -1

Query: 310 QEERHARESASYQEALARLEEEGQSLKEEMARHLQEYQDLLNVKLALDIEIATYRKLLEG 369
            + R   E   +   + +L+EE   L+ EM   L E Q L++ KL+L++EIA YRKLLE 
Sbjct: 257 HDPRDGPEDQDHTLEVNQLKEEMNKLRAEMEAMLVELQTLMDAKLSLELEIAAYRKLLET 78

Query: 370 EENRITIP 377
           EE+R  +P
Sbjct: 77  EESRTGLP 54
>19956
          Length = 536

 Score = 47.8 bits (112), Expect = 8e-06,   Method: Compositional matrix adjust.
 Identities = 33/87 (37%), Positives = 51/87 (58%), Gaps = 3/87 (3%)
 Frame = -3

Query: 126 QLTANSARL---EVERDNFAQDLGTLRQKLQDETNLRLEAENNLAAYRQEADEATLARVD 182
           QL   SA+L   +  R    +D+  LR +L  +       E  L   +Q+ +E TL RVD
Sbjct: 264 QLADLSAKLNDADAARARLQKDMSGLRSQLSSQ-------EQQLGTAKQQIEEETLLRVD 106

Query: 183 LERKVESLEEEIQFLRKIYEEEVRELR 209
           LE +V+SL+EE+QF  ++YE+E+ E+R
Sbjct: 105 LENRVQSLKEELQFKAQLYEQELEEVR 25
>26996
          Length = 386

 Score = 42.0 bits (97), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 29/108 (26%), Positives = 49/108 (45%), Gaps = 3/108 (2%)
 Frame = -1

Query: 32  PRFSLSRMTPPLPARVDFSLAGALNAGFKETRASERAEMMELNDRFASYIEKVRFLEQQN 91
           P  S  R  PP P R               TR  E+  +  LNDR A+YI++VRFLE +N
Sbjct: 284 PGSSRRRERPPSPTR--------------STRQQEQESLQGLNDRLANYIDRVRFLEAEN 147

Query: 92  KALAAELN---QLRAKEPTKLADVYQAXXXXXXXXXDQLTANSARLEV 136
             L+ ++    ++  +E + + ++Y+          D      AR+++
Sbjct: 146 SRLSTQVQSTEEIVKREVSSVKNLYETELADARRLLDDTAREKARIQI 3
>11942
          Length = 2252

 Score = 28.1 bits (61), Expect = 8.0,   Method: Compositional matrix adjust.
 Identities = 19/45 (42%), Positives = 26/45 (57%)
 Frame = +1

Query: 190  LEEEIQFLRKIYEEEVRELREQLAQQQVHVEMDVAKPDLTAALRE 234
            LEEE    +  YEEE++ LRE+L +Q+ +   DV   D  A L E
Sbjct: 1069 LEEEADEAKAGYEEEIKTLREKLRRQRTNT--DVQTADKVAKLEE 1197
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|149250224|ref|XP_485171.5| PREDICTED: myosin
regulatory light polypeptide 9 isoform 1 [Mus musculus]
         (118 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

20251                                                                 120   2e-28
05237                                                                  56   3e-09
01019                                                                  55   7e-09
14594                                                                  52   8e-08
14366                                                                  50   2e-07
26610                                                                  46   4e-06
16255                                                                  45   7e-06
18171                                                                  45   1e-05
19942                                                                  42   5e-05
07385                                                                  40   2e-04
11425                                                                  39   4e-04
18677                                                                  39   6e-04
38338                                                                  37   0.002
01491                                                                  37   0.002
14945                                                                  32   0.046
04067                                                                  32   0.058
22063                                                                  32   0.064
22273                                                                  32   0.090
34988                                                                  27   2.4  
04556                                                                  26   3.2  
06283                                                                  25   5.4  
04697                                                                  25   6.3  
28929                                                                  25   6.4  
22490                                                                  25   9.0  
>20251
          Length = 2203

 Score =  120 bits (300), Expect = 2e-28,   Method: Compositional matrix adjust.
 Identities = 77/153 (50%), Positives = 87/153 (56%), Gaps = 54/153 (35%)
 Frame = +3

Query: 20  SNVFAMFDQSQIQEFKEAFNMIDQNRDGFIDKEDLHDMLASLG-FIHEDHLREL------ 72
           SNVFAMFDQSQIQEFKEAFNMIDQNRDGFIDKEDL DMLASLG    E  L E+      
Sbjct: 123 SNVFAMFDQSQIQEFKEAFNMIDQNRDGFIDKEDLGDMLASLGKNPTEGQLDEMMNXAPG 302

Query: 73  -------LTTMGD----------------------------------------RFTDEEV 85
                  LT  GD                                        RFTD+EV
Sbjct: 303 PINFTMFLTMFGDKLNGTDPEDVIKNAFACFDEDGKGVIQEDRLRELLTTMGDRFTDDEV 482

Query: 86  DEMYREAPIDKKGNFNYVEFTRILKHGAKDKDD 118
           DEM+R+API K+GNF+Y+EFTRILK+G K+ D+
Sbjct: 483 DEMFRDAPI-KRGNFDYLEFTRILKYGKKENDE 578
>05237
          Length = 472

 Score = 56.2 bits (134), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 30/77 (38%), Positives = 44/77 (57%)
 Frame = +3

Query: 33  EFKEAFNMIDQNRDGFIDKEDLHDMLASLGFIHEDHLRELLTTMGDRFTDEEVDEMYREA 92
           E +EAF + D++ +GFI   +L               R ++T +G++ TDEEVDEM REA
Sbjct: 30  ELREAFRVFDKDGNGFISASEL---------------RHVMTNLGEKLTDEEVDEMIREA 164

Query: 93  PIDKKGNFNYVEFTRIL 109
            ID  G  NY EF +++
Sbjct: 165 DIDGDGQVNYEEFVKMM 215
>01019
          Length = 1705

 Score = 55.1 bits (131), Expect = 7e-09,   Method: Compositional matrix adjust.
 Identities = 28/61 (45%), Positives = 36/61 (59%), Gaps = 8/61 (13%)
 Frame = +1

Query: 62  GFIHEDHLRELLTTMGDRFTDEEVDEMYREAPIDKKGNFNYVEFTRIL--------KHGA 113
           GFI    LR ++T +G++ TDEEVDEM REA ID  G  NY EF  ++         HGA
Sbjct: 64  GFISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVTMMTSK*AVQSAHGA 243

Query: 114 K 114
           +
Sbjct: 244 R 246
>14594
          Length = 1014

 Score = 51.6 bits (122), Expect = 8e-08,   Method: Compositional matrix adjust.
 Identities = 27/78 (34%), Positives = 44/78 (56%)
 Frame = +3

Query: 32  QEFKEAFNMIDQNRDGFIDKEDLHDMLASLGFIHEDHLRELLTTMGDRFTDEEVDEMYRE 91
           +E +EAF + D++ +G+I   +L               R ++T +G++ TDEEVDEM +E
Sbjct: 660 EELREAFRVFDKDGNGYISAAEL---------------RHVMTNLGEKLTDEEVDEMIKE 794

Query: 92  APIDKKGNFNYVEFTRIL 109
           A +D  G  NY EF  ++
Sbjct: 795 ADLDGDGMVNYEEFVTMM 848
>14366
          Length = 499

 Score = 50.4 bits (119), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 22/51 (43%), Positives = 35/51 (68%)
 Frame = -3

Query: 62  GFIHEDHLRELLTTMGDRFTDEEVDEMYREAPIDKKGNFNYVEFTRILKHG 112
           G I+   LR +LT +G++ +DEEVDEM REA I   G  +Y +F +++++G
Sbjct: 206 GMINAAELRHVLTHLGEKLSDEEVDEMIREADISGDGQVSYNDFVKVMENG 54
>26610
          Length = 455

 Score = 45.8 bits (107), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 28/78 (35%), Positives = 39/78 (50%)
 Frame = +3

Query: 32  QEFKEAFNMIDQNRDGFIDKEDLHDMLASLGFIHEDHLRELLTTMGDRFTDEEVDEMYRE 91
           ++  EAFN ID+   GF+        +A+        LR LLT MGDR TDEE + +  E
Sbjct: 258 KQLDEAFNTIDKEGSGFV--------MAT-------ELRHLLTHMGDRITDEEFNALLEE 392

Query: 92  APIDKKGNFNYVEFTRIL 109
             +D  G     EF ++L
Sbjct: 393 LEVDSNGRVRRKEFVQLL 446

 Score = 27.3 bits (59), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 16/45 (35%), Positives = 23/45 (51%), Gaps = 1/45 (2%)
 Frame = +3

Query: 34 FKEAFNMIDQNRDGFIDKEDLHDMLASLGFIHEDH-LRELLTTMG 77
            EAF + D + DG I   ++   + SLG +  D  LR LL+  G
Sbjct: 48 VSEAFELFDTDNDGKIAASEVGTAIRSLGHVVTDSDLRRLLSKAG 182
>16255
          Length = 767

 Score = 45.1 bits (105), Expect = 7e-06,   Method: Compositional matrix adjust.
 Identities = 20/37 (54%), Positives = 26/37 (70%)
 Frame = -2

Query: 73  LTTMGDRFTDEEVDEMYREAPIDKKGNFNYVEFTRIL 109
           +T +G++ TDEEVDEM REA ID  G  NY EF  ++
Sbjct: 766 MTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVTMM 656
>18171
          Length = 1131

 Score = 44.7 bits (104), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 20/48 (41%), Positives = 32/48 (66%)
 Frame = +3

Query: 62  GFIHEDHLRELLTTMGDRFTDEEVDEMYREAPIDKKGNFNYVEFTRIL 109
           G I    LR +LTT+GD+ T EEV+E+ +EA  ++ G  +Y EF +++
Sbjct: 210 GVISTALLRHVLTTLGDQLTSEEVEELIKEADKEETGQVDYKEFIKMM 353
>19942
          Length = 367

 Score = 42.0 bits (97), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 18/31 (58%), Positives = 23/31 (74%)
 Frame = +2

Query: 72  LLTTMGDRFTDEEVDEMYREAPIDKKGNFNY 102
           ++T +G++ TDEEVDEM REA ID  G  NY
Sbjct: 2   VMTNLGEKLTDEEVDEMIREADIDGDGQVNY 94
>07385
          Length = 1292

 Score = 40.4 bits (93), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 18/31 (58%), Positives = 22/31 (70%)
 Frame = +3

Query: 79  RFTDEEVDEMYREAPIDKKGNFNYVEFTRIL 109
           + TDEEVDEM REA ID  G  NY EF +++
Sbjct: 150 KLTDEEVDEMIREADIDGDGQVNYEEFVKMM 242
>11425
          Length = 599

 Score = 39.3 bits (90), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 21/55 (38%), Positives = 32/55 (58%), Gaps = 2/55 (3%)
 Frame = -2

Query: 62  GFIHEDHLRELLTTMGDRFTDEEVDEMYREAPI--DKKGNFNYVEFTRILKHGAK 114
           GFI    LR LLT +G+R +D+EVDE+ +      D +GN  Y +F + +  G +
Sbjct: 286 GFISAAELRHLLTGLGERLSDDEVDELIKATDTREDLEGNVKYEDFIQKVLKGPE 122
>18677
          Length = 754

 Score = 38.5 bits (88), Expect = 6e-04,   Method: Compositional matrix adjust.
 Identities = 18/53 (33%), Positives = 31/53 (58%)
 Frame = +2

Query: 30  QIQEFKEAFNMIDQNRDGFIDKEDLHDMLASLGFIHEDHLRELLTTMGDRFTD 82
           +I+ ++E F   D+NR G +D  +L +M + LGF      R +LT++  R+ D
Sbjct: 500 EIKAYREVFLQFDKNRSGLVDTYELGNMFSKLGF---PVTRPVLTSIVRRYGD 649
>38338
          Length = 463

 Score = 37.0 bits (84), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 18/43 (41%), Positives = 28/43 (65%)
 Frame = -2

Query: 20  SNVFAMFDQSQIQEFKEAFNMIDQNRDGFIDKEDLHDMLASLG 62
           SN+     + QI EFKEAF++ D++ DG I  ++L  ++ SLG
Sbjct: 204 SNMADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLG 76
>01491
          Length = 1707

 Score = 37.0 bits (84), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 22/73 (30%), Positives = 35/73 (47%)
 Frame = +1

Query: 37  AFNMIDQNRDGFIDKEDLHDMLASLGFIHEDHLRELLTTMGDRFTDEEVDEMYREAPIDK 96
           AF ++D+   G I  ED               LR LL ++GD  T++E+++M  E   D 
Sbjct: 361 AFRVLDKGNKGVIPVED---------------LRWLLKSLGDDLTEDEIEDMIVETDTDG 495

Query: 97  KGNFNYVEFTRIL 109
            G  +Y EF  ++
Sbjct: 496 SGTVDYEEFRTLM 534
>14945
          Length = 1337

 Score = 32.3 bits (72), Expect = 0.046,   Method: Compositional matrix adjust.
 Identities = 23/90 (25%), Positives = 41/90 (45%)
 Frame = +1

Query: 28  QSQIQEFKEAFNMIDQNRDGFIDKEDLHDMLASLGFIHEDHLRELLTTMGDRFTDEEVDE 87
           + Q QE +EAF++ D +  G ID ++L   + +LGF  +                EE+ +
Sbjct: 100 EEQKQEIREAFDLFDADGSGTIDAKELKVAMRALGFEPK---------------KEEIKK 234

Query: 88  MYREAPIDKKGNFNYVEFTRILKHGAKDKD 117
           M  E   +  G  ++ +F  I+     +KD
Sbjct: 235 MIAEIDKEGTGTIDFNDFLTIMTQKMSEKD 324
>04067
          Length = 1920

 Score = 32.0 bits (71), Expect = 0.058,   Method: Compositional matrix adjust.
 Identities = 20/70 (28%), Positives = 33/70 (47%)
 Frame = -1

Query: 40   MIDQNRDGFIDKEDLHDMLASLGFIHEDHLRELLTTMGDRFTDEEVDEMYREAPIDKKGN 99
            ++D+   G I  EDL  +L SL               GD  T++E+++M  E   D  G 
Sbjct: 1920 VLDKGNKGVIPVEDLRWLLKSL---------------GDDLTEDEIEDMILETDTDGSGT 1786

Query: 100  FNYVEFTRIL 109
             +Y EF +++
Sbjct: 1785 VDYEEFYKLM 1756
>22063
          Length = 688

 Score = 32.0 bits (71), Expect = 0.064,   Method: Compositional matrix adjust.
 Identities = 23/90 (25%), Positives = 40/90 (44%)
 Frame = +3

Query: 28  QSQIQEFKEAFNMIDQNRDGFIDKEDLHDMLASLGFIHEDHLRELLTTMGDRFTDEEVDE 87
           + Q QE +EAF++ D +  G ID ++L   + +LGF                   EE+ +
Sbjct: 159 EEQKQEIREAFDLFDADGSGTIDAKELKVAMRALGF---------------EPKKEEIKK 293

Query: 88  MYREAPIDKKGNFNYVEFTRILKHGAKDKD 117
           M  E   +  G  ++ +F  I+     +KD
Sbjct: 294 MIAEIDKEGTGTIDFNDFLTIMTQKMSEKD 383
>22273
          Length = 297

 Score = 31.6 bits (70), Expect = 0.090,   Method: Compositional matrix adjust.
 Identities = 14/25 (56%), Positives = 17/25 (68%)
 Frame = +1

Query: 85  VDEMYREAPIDKKGNFNYVEFTRIL 109
           VDEM REA ID  G  NY EF +++
Sbjct: 1   VDEMIREADIDGDGQVNYEEFVKMM 75
>34988
          Length = 686

 Score = 26.6 bits (57), Expect = 2.4,   Method: Compositional matrix adjust.
 Identities = 11/25 (44%), Positives = 16/25 (64%)
 Frame = -2

Query: 55  HDMLASLGFIHEDHLRELLTTMGDR 79
           HD+L +LGFI  D +++  T   DR
Sbjct: 247 HDLLITLGFIFCDQVKKCATISRDR 173
>04556
          Length = 1816

 Score = 26.2 bits (56), Expect = 3.2,   Method: Composition-based stats.
 Identities = 16/39 (41%), Positives = 22/39 (56%), Gaps = 4/39 (10%)
 Frame = +1

Query: 41  IDQNRDGFID----KEDLHDMLASLGFIHEDHLRELLTT 75
           I+QNRD  I       DL D+   + +IHE H + +LTT
Sbjct: 406 INQNRDY*IQI*KVGGDLPDIFCKIVYIHETHSK*ILTT 522
>06283
          Length = 1162

 Score = 25.4 bits (54), Expect = 5.4,   Method: Compositional matrix adjust.
 Identities = 10/23 (43%), Positives = 15/23 (65%)
 Frame = -1

Query: 53  DLHDMLASLGFIHEDHLRELLTT 75
           DL D+   + +IHE H + +LTT
Sbjct: 895 DLPDIFCKIVYIHETHFK*ILTT 827
>04697
          Length = 559

 Score = 25.4 bits (54), Expect = 6.3,   Method: Compositional matrix adjust.
 Identities = 10/48 (20%), Positives = 26/48 (54%)
 Frame = +1

Query: 62  GFIHEDHLRELLTTMGDRFTDEEVDEMYREAPIDKKGNFNYVEFTRIL 109
           GF+  + LR     MG++ T++++ ++  E  + +    +  EF +++
Sbjct: 406 GFVTVNDLRRYFKKMGEKVTEDQLHDILSEVDLSRNAQVDLGEFLQLM 549
>28929
          Length = 424

 Score = 25.4 bits (54), Expect = 6.4,   Method: Compositional matrix adjust.
 Identities = 16/48 (33%), Positives = 23/48 (47%), Gaps = 4/48 (8%)
 Frame = +3

Query: 29  SQIQEFKEAFNMIDQNRDGF----IDKEDLHDMLASLGFIHEDHLREL 72
           S  Q  K+ F  +   R G     ++  D+H  LA +GF HE H+  L
Sbjct: 198 SVAQGLKQEFLQLFDGRRGVSALDLESLDVHGPLARVGFKHESHVALL 341
>22490
          Length = 743

 Score = 24.6 bits (52), Expect = 9.0,   Method: Compositional matrix adjust.
 Identities = 11/23 (47%), Positives = 15/23 (65%)
 Frame = -1

Query: 85  VDEMYREAPIDKKGNFNYVEFTR 107
           VDE+ RE  +DK G  +Y EF +
Sbjct: 467 VDEILREDDLDKDGYVDYTEFMK 399
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|30425320|ref|NP_780747.1| serine/threonine-protein
kinase NIM1 [Mus musculus]
         (436 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

17975                                                                 123   2e-28
15910                                                                 114   9e-26
00300                                                                 112   2e-25
13066                                                                 110   8e-25
01707                                                                 108   3e-24
18484                                                                 105   5e-23
12721                                                                 103   2e-22
14420                                                                 100   2e-21
13592                                                                  98   6e-21
21079                                                                  96   3e-20
30755                                                                  95   5e-20
27546                                                                  90   2e-18
18921                                                                  90   2e-18
09606                                                                  89   5e-18
09007                                                                  84   1e-16
21433                                                                  62   2e-16
38560                                                                  82   4e-16
03240                                                                  82   4e-16
29581                                                                  82   6e-16
01756                                                                  80   1e-15
21808                                                                  80   2e-15
01392                                                                  79   3e-15
04591                                                                  79   5e-15
14126                                                                  79   5e-15
06405                                                                  76   2e-14
31885                                                                  75   6e-14
00392                                                                  74   9e-14
19301                                                                  74   1e-13
18663                                                                  70   1e-12
20152                                                                  70   2e-12
00486                                                                  69   3e-12
01060                                                                  69   4e-12
14477                                                                  68   6e-12
11780                                                                  66   2e-11
01718                                                                  65   5e-11
27405                                                                  63   2e-10
17253                                                                  60   1e-09
13212                                                                  60   1e-09
14116                                                                  59   3e-09
01966                                                                  55   3e-09
12786                                                                  59   4e-09
04852                                                                  59   4e-09
19094                                                                  59   5e-09
26711                                                                  58   6e-09
29590                                                                  57   2e-08
26560                                                                  57   2e-08
37602                                                                  56   4e-08
19761                                                                  55   5e-08
07940                                                                  50   1e-06
07291                                                                  50   2e-06
12672                                                                  49   3e-06
31120                                                                  49   4e-06
04138                                                                  48   9e-06
28157                                                                  48   9e-06
28638                                                                  47   2e-05
11185                                                                  46   2e-05
00715                                                                  46   3e-05
03508                                                                  44   1e-04
17300                                                                  44   2e-04
18996                                                                  42   6e-04
17722                                                                  42   6e-04
26009                                                                  41   0.001
07833                                                                  41   0.001
36481                                                                  40   0.001
32957                                                                  40   0.002
16708                                                                  39   0.003
25019                                                                  39   0.003
17806                                                                  38   0.007
08294                                                                  38   0.007
28865                                                                  38   0.007
00394                                                                  38   0.007
32357                                                                  37   0.011
22005                                                                  37   0.012
31789                                                                  37   0.017
31489                                                                  37   0.018
13840                                                                  37   0.019
20655                                                                  37   0.023
18481                                                                  36   0.025
27274                                                                  36   0.026
01106                                                                  36   0.038
20559                                                                  35   0.043
20640                                                                  35   0.062
21210                                                                  34   0.11 
11404                                                                  33   0.31 
03795                                                                  33   0.33 
05627                                                                  32   0.44 
29360                                                                  31   0.92 
32000                                                                  31   1.2  
21800                                                                  29   3.4  
03665                                                                  28   6.8  
18830                                                                  28   7.9  
04981                                                                  28   8.0  
>17975
          Length = 449

 Score =  123 bits (308), Expect = 2e-28,   Method: Compositional matrix adjust.
 Identities = 63/138 (45%), Positives = 94/138 (68%), Gaps = 2/138 (1%)
 Frame = +3

Query: 84  NFSQVKLGIHSLTKEKVAIKILDKTKLDQKTQRLLSREISSMEKLHHPNIVRLYEVVETL 143
           +F+ VKL  H  T EKVA+K++DKTKLD+ ++  L +E+  M+ + HPN+VRLYEV++T 
Sbjct: 3   HFAVVKLARHVFTGEKVAVKVIDKTKLDEVSRSHLFQEVRCMKLVQHPNVVRLYEVIDTQ 182

Query: 144 SKLHLVMEYAGGGELFGKISTE-GKLSEPESKLIFSQILSAVKHMHENQIIHRDLKAEN- 201
           +KL+L++E   GG+++  I    G L E  +K  F QI+ A+ + H+  ++HRDLK EN 
Sbjct: 183 TKLYLILELGDGGDMYDYIMRHSGGLEEKLAKRYFRQIVEAISYCHKLHVVHRDLKPENV 362

Query: 202 VFYTSRTCVKVGDFGFST 219
           VF+     VK+ DFGFST
Sbjct: 363 VFFEKPGLVKLTDFGFST 416
>15910
          Length = 1361

 Score =  114 bits (284), Expect = 9e-26,   Method: Compositional matrix adjust.
 Identities = 60/183 (32%), Positives = 101/183 (55%), Gaps = 7/183 (3%)
 Frame = +2

Query: 157 ELFGKISTEGKLSEPESKLIFSQILSAVKHMHENQIIHRDLKAENVFY---TSRTCVKVG 213
           ELF +I T G+ +E ++    S IL  V+++H N ++HRDLK EN+ Y   T  + +K+ 
Sbjct: 422 ELFDRIVTRGQYTEKDAARAISDILHGVQYIHANGVVHRDLKPENLLYECMTDDSKLKLA 601

Query: 214 DFGFSTVSKKGEMLNTFCGSPPYAAPELFRDQHYVGVYVDIWALGVLLYFMVTGTMPFRA 273
           DFG S + +    ++T CG+P Y APE+ +   Y    VD+W++GV+ Y ++ G  PF A
Sbjct: 602 DFGLSRIIEPEVQMSTVCGTPGYCAPEVLKGDKYTPS-VDMWSVGVIAYILLCGYEPFFA 778

Query: 274 ETVAKLKKSILEGTYTIPQ----HVSEPCHRLIRGVLQPTPTERYGINYIMSNEWMRGVP 329
           E   ++ + I++G Y   +     +SE    ++R +L   P +R      +   W++GV 
Sbjct: 779 ENEFEMYRKIIKGEYKFDEEYWSEISENAKDVVRKLLVIDPKKRLTATEALRLPWVKGVA 958

Query: 330 YPT 332
             T
Sbjct: 959 TKT 967
>00300
          Length = 2318

 Score =  112 bits (281), Expect = 2e-25,   Method: Compositional matrix adjust.
 Identities = 76/213 (35%), Positives = 108/213 (50%), Gaps = 10/213 (4%)
 Frame = -1

Query: 69   KRIGFYRIRG-EIGSGNFSQVKLGIHSLTKEKVAIKILDKTKLDQKTQRLLSREISSMEK 127
            +R+ F   RG +IG G F +V   ++  T E +A+K +     D +  R +  EI   E 
Sbjct: 1670 RRVNFRWQRGNKIGEGQFGKVYTAVNMSTGELMALKEMKFQPNDLQQLREMCDEIKIFEG 1491

Query: 128  LHHPNIVRLYEVVETLSKLHLVMEYAGGGELFGKISTEGKLSEPES--KLIFSQILSAVK 185
            + H N+V+ Y V     ++ + MEY   G     I    K+  PE   +    +I+ AV 
Sbjct: 1490 IQHENLVKYYGVEVHKDEMLMFMEYCDTG----TIEEAAKMGLPEYLIRRYTREIVLAVN 1323

Query: 186  HMHENQIIHRDLKAENVFYTSRTCVKVGDFGFSTVSKK-----GEMLNTFCGSPPYAAPE 240
            H+HEN I+HRD+K  N+F TS   VK+GDFG S   K      GE  N   G+  Y APE
Sbjct: 1322 HLHENSIVHRDIKGANIFLTSNGHVKLGDFGCSVKLKSHTTMPGEFHN-LVGTTAYMAPE 1146

Query: 241  LF--RDQHYVGVYVDIWALGVLLYFMVTGTMPF 271
            +F   DQ   G   DIW+LG ++  M TG  P+
Sbjct: 1145 VFTQNDQGGYGRAADIWSLGCVVIEMATGKRPW 1047
>13066
          Length = 551

 Score =  110 bits (276), Expect = 8e-25,   Method: Compositional matrix adjust.
 Identities = 58/165 (35%), Positives = 94/165 (56%), Gaps = 5/165 (3%)
 Frame = +3

Query: 99  KVAIKILDKTKLD-QKTQRLLSREISSMEKLHHPNIVRLYEVVETLSKLHLVMEYAGGGE 157
           K+A KI+DK K      ++   RE+  + KL HP I++++ +++   K  + M +A  G+
Sbjct: 57  KLACKIIDKEKAPVDFVEKFFPRELDLLTKLDHPYIIQIHSILQRXPKNFIFMRFAERGD 236

Query: 158 LFGKISTEGKLSEPESKLIFSQILSAVKHMHENQIIHRDLKAENVFYTSRTCVKVGDFGF 217
           L   I   G + E ++K+ F Q+ +A+ ++H   + HRDLK EN+  +S   VK+ DFGF
Sbjct: 237 LLTYIQEVGFVKEKQAKIWFYQMTTALNYLHSYDVAHRDLKCENILLSSHFNVKLADFGF 416

Query: 218 --STVSKKGE--MLNTFCGSPPYAAPELFRDQHYVGVYVDIWALG 258
             + +++ GE  M  T+CGS  YAAPE+     Y     D W+LG
Sbjct: 417 ACACITESGEKYMSRTYCGSAAYAAPEIVYGAPYAPKVADAWSLG 551
>01707
          Length = 757

 Score =  108 bits (271), Expect = 3e-24,   Method: Compositional matrix adjust.
 Identities = 67/191 (35%), Positives = 100/191 (52%), Gaps = 1/191 (0%)
 Frame = +1

Query: 78  GEIGSGNFSQVKLGIHSLTKEKVAIKILDKTKLDQKTQRLLSREISSMEKLHHPNIVRLY 137
           G+IG G++  V    +  T + VAIK   +++ D   +++  REI  +++L HPN+VRL 
Sbjct: 82  GKIGEGSYGVVFKCRNKETSQLVAIKKFVESEDDPLIKKIAMREIRMLKQLKHPNLVRLI 261

Query: 138 EVVETLSKLHLVMEYAGGGELFGKISTEGKLSEPESKLIFSQILSAVKHMHENQIIHRDL 197
           EV     +LHLV +Y     L         L EP  K I  Q L AV   H+   IHRD+
Sbjct: 262 EVFRRKKRLHLVFDYVDHTLLNELDRYPRGLPEPMVKRIIYQTLLAVNFCHQYNTIHRDV 441

Query: 198 KAENVFYTSRTCVKVGDFGFSTV-SKKGEMLNTFCGSPPYAAPELFRDQHYVGVYVDIWA 256
           K EN+  T +  VK+ DFGF+ + +  G+    +  +  Y APEL       G  VD+WA
Sbjct: 442 KPENILITRQGQVKLCDFGFARILTGPGDEYTDYVATRWYRAPELLVGDTQYGPPVDVWA 621

Query: 257 LGVLLYFMVTG 267
           +G +   ++TG
Sbjct: 622 IGCVFAELLTG 654
>18484
          Length = 635

 Score =  105 bits (261), Expect = 5e-23,   Method: Compositional matrix adjust.
 Identities = 59/160 (36%), Positives = 84/160 (52%), Gaps = 1/160 (0%)
 Frame = +1

Query: 157 ELFGKISTEGKLSEPESKLIFSQILSAVKHMHENQIIHRDLKAENVFYTSRTCVKVGDFG 216
           +L  +I  EGK  EP +    ++I   +  +H+  II+RDLK +NV   S   +K+ DFG
Sbjct: 1   DLMYRIQQEGKFKEPVAAFYAAEIAVGLFFLHDQGIIYRDLKLDNVMLDSEGHIKIADFG 180

Query: 217 FSTVSKKGEMLN-TFCGSPPYAAPELFRDQHYVGVYVDIWALGVLLYFMVTGTMPFRAET 275
                  G+    TFCG+P Y APE+   Q Y    VD WA GVLL+ M+ G  PF  E 
Sbjct: 181 MCKEGMTGDATTRTFCGTPDYIAPEIVLYQPYSKS-VDWWAYGVLLFEMLAGQPPFDGED 357

Query: 276 VAKLKKSILEGTYTIPQHVSEPCHRLIRGVLQPTPTERYG 315
             +L  SI +   + P+ +S     L +G+L   PT+R G
Sbjct: 358 EDELFSSITDHNVSYPKAMSREAVSLCKGLLMKNPTKRLG 477
>12721
          Length = 821

 Score =  103 bits (256), Expect = 2e-22,   Method: Compositional matrix adjust.
 Identities = 68/220 (30%), Positives = 112/220 (50%), Gaps = 1/220 (0%)
 Frame = +1

Query: 65  ITLGKRIGFYRIRGEIGSGNFSQVKLGIHSLTKEKVAIKILDKTKLDQKTQRLLSREISS 124
           +T G    F     +IG G+   V +   S    ++A+K +D  K  Q+ + LL  E+  
Sbjct: 67  VTPGDPRTFLDDFMKIGEGSTGIVCIAT-SRDGRQMAVKKMDLRK--QQRRELLFNEVVV 237

Query: 125 MEKLHHPNIVRLYEVVETLSKLHLVMEYAGGGELFGKISTEGKLSEPESKLIFSQILSAV 184
           M   HHPNIV +Y       +L +VME+  GG L   I T  ++ E +   +    L A+
Sbjct: 238 MRDYHHPNIVEMYNSYLVNDELWVVMEFMEGGAL-TDIVTNNRMDEVQIATVCRACLKAL 414

Query: 185 KHMHENQIIHRDLKAENVFYTSRTCVKVGDFGF-STVSKKGEMLNTFCGSPPYAAPELFR 243
             +H N +IHRD+K++++  +    VK+ DFGF + V++  +   +  G+P + APE+  
Sbjct: 415 AFLHANGVIHRDIKSDSILLSHDGKVKLXDFGFCAQVTQDLQKRKSLVGTPYWMAPEVIS 594

Query: 244 DQHYVGVYVDIWALGVLLYFMVTGTMPFRAETVAKLKKSI 283
              Y G  VDIW+LG+++  M+    PF  E   +  + I
Sbjct: 595 RLPY-GPEVDIWSLGIMVMEMIDAEPPFFNEPPLQAMRRI 711
>14420
          Length = 528

 Score = 99.8 bits (247), Expect = 2e-21,   Method: Compositional matrix adjust.
 Identities = 57/165 (34%), Positives = 91/165 (55%), Gaps = 1/165 (0%)
 Frame = +2

Query: 112 QKTQRLLSREISSMEKLHHPNIVRLYEVVETLSKLHLVMEYAGGGELFGKISTEGKLSEP 171
           Q  + L+  EI  M +  +PNIV   +      +L +VME+  GG L   + TE  + E 
Sbjct: 23  QPKKELIINEILVMRENQNPNIVNYLDSYLVGEELWVVMEFLAGGSL-TDVVTETCMDEG 199

Query: 172 ESKLIFSQILSAVKHMHENQIIHRDLKAENVFYTSRTCVKVGDFGF-STVSKKGEMLNTF 230
           +   +  + L A++ +HENQ+IHRD+K++N+       VK+ DFGF + +S +    +T 
Sbjct: 200 QIAAVCRECLQALEFLHENQVIHRDIKSDNILLGMDGSVKLTDFGFCAQLSPEQSKRSTM 379

Query: 231 CGSPPYAAPELFRDQHYVGVYVDIWALGVLLYFMVTGTMPFRAET 275
            G+P + APE+   + Y G  VDIW+LGV+   M+ G  P+  E 
Sbjct: 380 VGTPYWMAPEVVTRKQY-GPTVDIWSLGVMCIEMIEGEPPYLNEN 511
>13592
          Length = 980

 Score = 98.2 bits (243), Expect = 6e-21,   Method: Compositional matrix adjust.
 Identities = 72/248 (29%), Positives = 120/248 (48%), Gaps = 13/248 (5%)
 Frame = +2

Query: 79  EIGSGNFSQVKLGIHSLTKEKVAIKILDKTKLDQKTQRLLSREISSMEKLHHPNIVRLYE 138
           +IG G F +V   +++ T E +A+K +     + +  + ++ E+  +E + H N+VR Y 
Sbjct: 5   KIGQGRFGKVYTAVNNNTGELMAMKEIAIQPGETRALKNVAEELKILEGIKHKNLVRYYG 184

Query: 139 VVETLSKLHLVMEYAGGGELFGKISTEGKLSEPESKLIFSQILSAVKHMHENQIIHRDLK 198
           +     +L + ME    G L   +   G L E  S+   +Q+LS V  +H++ I+HRD+K
Sbjct: 185 IEVHREELLIFMELCSEGTLESLVELTGGLPEALSRRFTAQLLSGVAELHKHGIVHRDIK 364

Query: 199 AENVFYT-SRTCVKVGDFGFST-----VSKKGEMLNTFCGSPPYAAPELF----RDQHYV 248
             N+F       +K+GDFG +       +  GE L  + G+  Y APE+F     D H  
Sbjct: 365 TANIFLVDGSNSLKLGDFGSAVKIQAHTTVPGE-LQGYVGTQAYMAPEVFTKTNSDGH-- 535

Query: 249 GVYVDIWALGVLLYFMVTGTMP---FRAETVAKLKKSILEGTYTIPQHVSEPCHRLIRGV 305
           G   DIW++G ++  M +G  P   F +      K  + E     P+ +S+  H  I   
Sbjct: 536 GRLADIWSVGCVVVEMASGKRPWAQFDSNFQIMFKVGMGEKPQA-PESLSQEGHDFIDHC 712

Query: 306 LQPTPTER 313
           LQ  P +R
Sbjct: 713 LQHDPKQR 736
>21079
          Length = 878

 Score = 95.9 bits (237), Expect = 3e-20,   Method: Compositional matrix adjust.
 Identities = 52/152 (34%), Positives = 82/152 (53%), Gaps = 3/152 (1%)
 Frame = +1

Query: 130 HPNIVRLYEVVETLSKLHLVMEYAGGGELFGK-ISTEGKLSEPESKLIFSQILSAVKHMH 188
           HP ++ L++  E    + LVME+ G GELF + I  +  L+E +      QI S V +MH
Sbjct: 1   HPKLLMLWDAFEAPRTMVLVMEFVGAGELFERVIRDDFVLTERDCVHFVRQICSGVGYMH 180

Query: 189 ENQIIHRDLKAENVFYTSRTC--VKVGDFGFSTVSKKGEMLNTFCGSPPYAAPELFRDQH 246
              I+H DLK ENV   S     +K+ DFG +   K G+ L    G+P + APE+  +  
Sbjct: 181 TQSILHLDLKPENVLCVSDNSNQIKIIDFGLARFYKPGDSLQVLFGTPEFIAPEVV-NYD 357

Query: 247 YVGVYVDIWALGVLLYFMVTGTMPFRAETVAK 278
            +    D+W++GV+ Y +++G  P R  T+ +
Sbjct: 358 EINFTTDMWSIGVICYILLSGLSPSRVTTMLR 453
>30755
          Length = 1137

 Score = 95.1 bits (235), Expect = 5e-20,   Method: Compositional matrix adjust.
 Identities = 53/155 (34%), Positives = 79/155 (50%), Gaps = 1/155 (0%)
 Frame = +2

Query: 162 ISTEGKLSEPESKLIFSQILSAVKHMHENQIIHRDLKAENVFYTSRTCVKVGDFGFSTVS 221
           +S E   +E  ++   ++I+SA+ ++H   II+RDLK EN+       +KV DFG     
Sbjct: 5   LSHERIFTEERTRFYGAEIISALGYLHSQGIIYRDLKLENLLLDKDGHIKVADFGLCKED 184

Query: 222 -KKGEMLNTFCGSPPYAAPELFRDQHYVGVYVDIWALGVLLYFMVTGTMPFRAETVAKLK 280
              G    TFCG+P Y APE+  D  Y G  VD W  GV++Y M+ G +PF       L 
Sbjct: 185 ITYGRTTKTFCGTPEYLAPEVLDDNDY-GRAVDWWGTGVVMYEMICGRLPFYNRDHDVLF 361

Query: 281 KSILEGTYTIPQHVSEPCHRLIRGVLQPTPTERYG 315
             IL      P+++++    L+ G+L   P  R G
Sbjct: 362 TLILVEDVKFPRNITDEAKSLLSGLLAKDPRNRLG 466
>27546
          Length = 426

 Score = 90.1 bits (222), Expect = 2e-18,   Method: Composition-based stats.
 Identities = 41/120 (34%), Positives = 73/120 (60%), Gaps = 1/120 (0%)
 Frame = -1

Query: 100 VAIKILDKTKLD-QKTQRLLSREISSMEKLHHPNIVRLYEVVETLSKLHLVMEYAGGGEL 158
           +A KI+DK K      ++   RE+  + +L HPNI++++ +++   K+ + M YA  G++
Sbjct: 396 LACKIIDKAKAPIDFVKKFFPRELEILTRLDHPNIIQIHSILQRGPKIFIFMRYAEKGDM 217

Query: 159 FGKISTEGKLSEPESKLIFSQILSAVKHMHENQIIHRDLKAENVFYTSRTCVKVGDFGFS 218
              I   G + E ++K+ F Q+  A++++H + I HRDLK EN+  + R  VK+ DFGF+
Sbjct: 216 LSHIKKTGPIDEAQTKVWFFQMAKALQYLHSHDIAHRDLKCENILLSKRLNVKIADFGFA 37
>18921
          Length = 697

 Score = 89.7 bits (221), Expect = 2e-18,   Method: Compositional matrix adjust.
 Identities = 63/209 (30%), Positives = 104/209 (49%), Gaps = 6/209 (2%)
 Frame = +2

Query: 74  YRIRGEIGSGNFSQVKLGIHSLTKEKVAIKILDKTKLDQKTQRLLSREISSMEKLHHPNI 133
           + I G++G G++  V   +H  T + +AIK   +  +D   Q ++ +EIS M++     I
Sbjct: 35  FDILGKLGEGSYGSVFKSLHKETGQVLAIK---QVPVDTDLQEII-KEISIMQQCDSKYI 202

Query: 134 VRLYEVVETLSKLHLVMEYAGGGELFGKISTEGK-LSEPESKLIFSQILSAVKHMHENQI 192
           V+ Y      + L +VMEY G G +   +    K L E E   I    L  + ++H  + 
Sbjct: 203 VKYYGSYFKNTDLWIVMEYCGAGSVSDIMRLRNKTLVEREIATILYYTLKGLXYLHSRRK 382

Query: 193 IHRDLKAENVFYTSRTCVKVGDFGFS-----TVSKKGEMLNTFCGSPPYAAPELFRDQHY 247
           IHRD+KA N+   +    K+ DFG +     T++K+    NT  G+P + APE+ ++  Y
Sbjct: 383 IHRDIKAGNILLNNEGHAKLADFGVAGQLTDTMAKR----NTVIGTPYWMAPEVIQEIGY 550

Query: 248 VGVYVDIWALGVLLYFMVTGTMPFRAETV 276
             V  DIW+LG+    M  G  P    ++
Sbjct: 551 DCV-ADIWSLGITALEMAEGKPPVMETSI 634
>09606
          Length = 1300

 Score = 88.6 bits (218), Expect = 5e-18,   Method: Compositional matrix adjust.
 Identities = 67/247 (27%), Positives = 111/247 (44%), Gaps = 24/247 (9%)
 Frame = -3

Query: 70   RIGFYRIRGEIGSGNFSQVKLGIHSLTKEKVAIKILDKTKLDQKTQRL-LSREISSMEKL 128
            R+  + +  E+G G  S +  G    T   VAI  ++K K  + T  + ++ +IS     
Sbjct: 1121 RMENFVLYEELGKGEHSIIYKGRRKGTINFVAIHCIEKCKRPEVTNTVRMTHDIS----- 957

Query: 129  HHPNIVRLYEVVETLSKLHLVMEYAGGGELFGKISTEGKLSEPESKLIFSQILSAVKHMH 188
             HPN+V+ +E  ET + L LV+E   GG L   ++ +  L E   +     +++ + ++H
Sbjct: 956  -HPNVVQFHEWYETSNHLWLVVELCTGGSLADILAQDHHLPETSIRDFGIHLVTGLHYIH 780

Query: 189  ENQIIHRDLKAENVFYTSRTCVKVGDFGFSTV------------SKKGEMLNT------- 229
               I+  DL+   V   +   +K  DFG S V            ++ G+  N        
Sbjct: 779  SLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEAGDQWNIQSAEEMM 600

Query: 230  ----FCGSPPYAAPELFRDQHYVGVYVDIWALGVLLYFMVTGTMPFRAETVAKLKKSILE 285
                  GSP Y APE+F+      +  D+WALG + Y M +G  PF  ET    K  +L 
Sbjct: 599  KQVPTSGSPTYMAPEVFQGAE-PSIMSDLWALGCVFYEMFSGHPPFLGETYDITKDKVLN 423

Query: 286  GTYTIPQ 292
              + +P+
Sbjct: 422  KEFPLPK 402
>09007
          Length = 1440

 Score = 84.0 bits (206), Expect = 1e-16,   Method: Compositional matrix adjust.
 Identities = 63/206 (30%), Positives = 98/206 (47%), Gaps = 14/206 (6%)
 Frame = -1

Query: 80  IGSGNFSQVKLGI---HSLTKEKVAIKILDKTKLDQKTQRLLSREISSMEKLHHPNIVRL 136
           +G G+F  V+  I    S  K +VA+K L K K+ +  Q  L +E + M+ L H NIVR+
Sbjct: 855 LGQGHFGTVRQAIWTAESGEKVQVAVKCLSKDKIHKDGQEFL-KETAIMQMLDHENIVRV 679

Query: 137 YEVV-ETLSKLHLVMEYAGGGELF---GKISTEGKLSEPESKLIFSQILSAVKHMHENQI 192
           Y VV +  + + LV E A    L     ++S     S P       Q+   + ++   ++
Sbjct: 678 YGVVMDNGADIMLVTELAPMRSLLECVKEVSARVDFSVPRLCDFSQQVCDGMSYLESKRL 499

Query: 193 IHRDLKAENVFYTSRTCVKVGDFGFSTVSKKG------EMLNTFCGSPPYAAPELFRDQH 246
           +HRDL A N+   S++ VK+ D G S     G      +       +  + APE FR+  
Sbjct: 498 VHRDLAARNILLFSKSKVKISDVGVSGALGAGKEYYQSQQTIHLQNAVAWCAPESFRNLC 319

Query: 247 YVGVYVDIWALGVLLY-FMVTGTMPF 271
           +     D+WA GVLL+ F   G  P+
Sbjct: 318 FSSAS-DVWAFGVLLWEFFTHGFQPW 244
>21433
          Length = 590

 Score = 62.4 bits (150), Expect(2) = 2e-16,   Method: Compositional matrix adjust.
 Identities = 41/129 (31%), Positives = 64/129 (49%)
 Frame = +2

Query: 179 QILSAVKHMHENQIIHRDLKAENVFYTSRTCVKVGDFGFSTVSKKGEMLNTFCGSPPYAA 238
           Q+ SA+++ H  ++IHRD+K EN+    +  +K+ DFG+S V        T CG+  Y  
Sbjct: 191 QLSSALEYCHYRKVIHRDIKPENLLLGLKGDLKIADFGWS-VHAPSSRRTTMCGTLDYLP 367

Query: 239 PELFRDQHYVGVYVDIWALGVLLYFMVTGTMPFRAETVAKLKKSILEGTYTIPQHVSEPC 298
           PE+   + +    VD+W+LGVL Y  + GT P R         +    T   P  V+   
Sbjct: 368 PEMVEGKTH-DENVDLWSLGVLCYEFLVGTPPLRPSPTRPPTPASPRWTSGSPSIVTPGA 544

Query: 299 HRLIRGVLQ 307
             LI  +L+
Sbjct: 545 RDLISKLLR 571

 Score = 41.2 bits (95), Expect(2) = 2e-16,   Method: Compositional matrix adjust.
 Identities = 19/61 (31%), Positives = 34/61 (55%)
 Frame = +3

Query: 118 LSREISSMEKLHHPNIVRLYEVVETLSKLHLVMEYAGGGELFGKISTEGKLSEPESKLIF 177
           L REI     L H NI+R++      ++++L++E+A  GEL+ ++    K  E E   I+
Sbjct: 9   LRREIEIQSHLRHDNILRMFGYFHDKTRVYLILEFAPKGELYKELQRCHKFDENEQHAIY 188

Query: 178 S 178
           +
Sbjct: 189 T 191
>38560
          Length = 479

 Score = 82.0 bits (201), Expect = 4e-16,   Method: Compositional matrix adjust.
 Identities = 43/114 (37%), Positives = 63/114 (55%), Gaps = 3/114 (2%)
 Frame = -3

Query: 215 FGFSTVSKKGEM---LNTFCGSPPYAAPELFRDQHYVGVYVDIWALGVLLYFMVTGTMPF 271
           FG      KG M   L T CGSP YAAPEL     Y+G   DIW++GVLLY ++ G +PF
Sbjct: 459 FGTLCA*PKGGMDHHLTTCCGSPAYAAPELISGLEYLGSEADIWSMGVLLYALLCGYLPF 280

Query: 272 RAETVAKLKKSILEGTYTIPQHVSEPCHRLIRGVLQPTPTERYGINYIMSNEWM 325
             E  + L +   +    +P+ +SE   +L+ G+LQ  P+ R  I  ++ + W+
Sbjct: 279 DDEKXSHL*QKNQKRKDEVPEWLSEDTTKLLEGMLQTDPSHRITIRRLLDHHWL 118
>03240
          Length = 1683

 Score = 82.0 bits (201), Expect = 4e-16,   Method: Compositional matrix adjust.
 Identities = 79/328 (24%), Positives = 147/328 (44%), Gaps = 57/328 (17%)
 Frame = -3

Query: 80   IGSGNFSQVKLGIHSLTKEKVAIKILDKTKLDQKTQRL-LSREISSMEKLHHPNIVRLYE 138
            +G G F +V L   + T    A+K L K+ + ++ Q   +  E   + +  +  +V+LY 
Sbjct: 1267 LGVGAFGEVSLCRKNDTGMLYAMKTLRKSDVLKRNQVAHVKAERDILAEADNEWVVKLYY 1088

Query: 139  VVETLSKLHLVMEYAGGGELFGKISTEGKLSEPESKLIFSQILSAVKHMHENQIIHRDLK 198
              +  + L+ VM+Y  GG+L G +     L EP ++   ++++ A++ +H    IHRD+K
Sbjct: 1087 SFQDHNYLYFVMDYVPGGDLMGLLIRMEILDEPLARFYVAELVQAIESVHRMGFIHRDIK 908

Query: 199  AENVFYTSRTCVKVGDFGFST--------------------------------------- 219
             +N+       +K+ DFG  T                                       
Sbjct: 907  PDNILIDRNGHIKLTDFGLCTGFRWTHNSKYYQRDGTHARQDSMEVKCQLDEQCQCEILK 728

Query: 220  ---VSKKGE---MLNTFCGSPPYAAPE-LFRDQHYVGVYVDIWALGVLLYFMVTGTMPFR 272
                 +K E   + ++  G+P Y APE L R   Y  V  D W++GV+L+ M+ G  PF 
Sbjct: 727  PLERRRKREQRCLAHSLVGTPNYIAPEVLSRLGGYTSV-CDWWSVGVILFEMLVGHPPFY 551

Query: 273  AETVAKLKKSIL--EGTYTIPQ--HVSEPCHRLIRGVLQPTPTERYGIN---YIMSNEWM 325
            A T A+ +  ++  +    IP+  ++S+P   LI  +   +  +R G+N    I ++ + 
Sbjct: 550  ANTPAETQYKVINWKDMLKIPRESNLSQPAKDLILRLCCGS-DDRLGLNGAGEIKTHMFF 374

Query: 326  RGVPYPTPLE---PFQLDPKHLSETSTL 350
             GV + T  +   P+  + ++ ++TS  
Sbjct: 373  AGVNFETLRKQQPPYVPNIRYATDTSNF 290
>29581
          Length = 1278

 Score = 81.6 bits (200), Expect = 6e-16,   Method: Compositional matrix adjust.
 Identities = 69/249 (27%), Positives = 105/249 (42%), Gaps = 33/249 (13%)
 Frame = -2

Query: 128  LHHPNIVRLYEVV--ETLSKLHLVMEYAGGGELFGKISTEGKLSEPESKLIFSQILSAVK 185
            L H NIV+L EVV  ++L  L LVMEY          +     SE + K I  Q+L  ++
Sbjct: 1184 LRHQNIVQLQEVVVGKSLDSLFLVMEYCEQDLASLLDNMPAPFSESQVKCIVLQLLKGLR 1005

Query: 186  HMHENQIIHRDLKAENVFYTSRTCVKVGDFGFS-TVSKKGEMLNTFCGSPPYAAPELFRD 244
            ++HE  IIHRDLK  N+  T + CVK+ DFG +    K  + +     +  Y APEL   
Sbjct: 1004 YLHEAFIIHRDLKVSNLLMTDKGCVKIADFGLARNYGKPQKPMTPKVVTLWYRAPELLFG 825

Query: 245  QHYVGVYVDIWALGVLLYFMV--TGTMPFRA---------ETVAKLKKSILEGTYTIPQH 293
                   +D+W+ G +L  ++     MP R+         E +     +I  G   +P  
Sbjct: 824  SKTHSTAIDMWSAGCILGELLGHKPLMPGRSDLQQIELIMELLGTPNDTIWPGFSQLPAF 645

Query: 294  -------------------VSEPCHRLIRGVLQPTPTERYGINYIMSNEWMRGVPYPTPL 334
                               +SE   RL+ G+    P +R      + + + +  PYP   
Sbjct: 644  EQFTLKKQPYNNLRHTFPWLSESGIRLLNGLFMYHPQKRATAEDCLEHSYFKEQPYPCDP 465

Query: 335  EPFQLDPKH 343
            E     P+H
Sbjct: 464  EFMPSFPQH 438
>01756
          Length = 1858

 Score = 80.5 bits (197), Expect = 1e-15,   Method: Compositional matrix adjust.
 Identities = 66/254 (25%), Positives = 112/254 (44%), Gaps = 15/254 (5%)
 Frame = -3

Query: 28   SCQTEGGKDSEEDQQRQLTPFEKLTQDMCQDEKVVREITLGKRIGFYRIRGEIGSGNFSQ 87
            S      ++ E+   ++ +P+E L    C ++              Y    +IG G F +
Sbjct: 1838 SSTASASREREQKDSQRYSPYETLKFPFCDED------------AKYEKLAKIGQGTFGE 1695

Query: 88   VKLGIHSLTKEKVAIK--ILDKTKLDQKTQRLLSREISSMEKLHHPNIVRLYEVVETL-- 143
            V       TK+ VA+K  ++D  K       L  REI  ++ L+H N+V L E+  T   
Sbjct: 1694 VFKARCKKTKQVVAMKKVLMDNEKEGFPITAL--REIKILQLLNHENVVDLIEICSTKAT 1521

Query: 144  ------SKLHLVMEYAGGGELFGKISTEGKL-SEPESKLIFSQILSAVKHMHENQIIHRD 196
                  S  +LV E+    +L G +S    + + PE K +  Q+++ + ++H N+I+HRD
Sbjct: 1520 SANRYKSMFYLVFEFCEH-DLAGLLSNMSVVFNLPEIKEVMKQLMNGLYYIHRNKILHRD 1344

Query: 197  LKAENVFYTSRTCVKVGDFG----FSTVSKKGEMLNTFCGSPPYAAPELFRDQHYVGVYV 252
            +KA N+  T +  +K+ DFG    FS   ++         +  Y  PEL          +
Sbjct: 1343 MKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRVVTLWYRPPELLLGDRNYSTAI 1164

Query: 253  DIWALGVLLYFMVT 266
            D W  G ++  M T
Sbjct: 1163 DQWGAGCIMAEMWT 1122
>21808
          Length = 1011

 Score = 79.7 bits (195), Expect = 2e-15,   Method: Compositional matrix adjust.
 Identities = 58/196 (29%), Positives = 90/196 (45%), Gaps = 4/196 (2%)
 Frame = +1

Query: 100 VAIKILDKTKLDQKTQRLLSREISSMEKLHHPNIVRLYEVVETLSKLHLVMEYAGGGELF 159
           VAIK L    +D K       E   M+KL HP +++LY V      + ++ E    G L 
Sbjct: 28  VAIKTLKSGTMDPKD---FLAEAQIMKKLRHPKLIQLYAVCTQDDPIFIITELMKNGSLL 198

Query: 160 GKISTEGK-LSEPESKLIFSQILSAVKHMHENQIIHRDLKAENVFYTSRTCVKVGDFGFS 218
             +  +G+ L  P    I +QI   + ++     IHRDL A N+  +    VK+ DFG +
Sbjct: 199 EFLQGKGRVLKLPALIDIGAQIACGMAYLESQNYIHRDLAARNILVSDNNTVKIADFGLA 378

Query: 219 TVSKKGEMLNTFCGSPP--YAAPELFRDQHYVGVYVDIWALGVLLYFMVT-GTMPFRAET 275
            V K+ E         P  + APE      +  +  D+W+ G+LL   VT G +P+   T
Sbjct: 379 RVIKEDEYEARVGARFPIKWTAPEAANYNRFT-IKSDVWSFGILLTETVTYGRVPYPGMT 555

Query: 276 VAKLKKSILEGTYTIP 291
            A++   +  G Y +P
Sbjct: 556 NAEVLHQVEHG-YRMP 600
>01392
          Length = 1806

 Score = 79.3 bits (194), Expect = 3e-15,   Method: Compositional matrix adjust.
 Identities = 68/238 (28%), Positives = 102/238 (42%), Gaps = 32/238 (13%)
 Frame = -1

Query: 166  GKLSEPESKLIFSQILSAVKHMHENQIIHRDLKAENVF---YTSRTCVKVGDFGFST-VS 221
            G L E E+ L+   I  A+  +H   I HRDLK EN+          VK+ DF  ++ +S
Sbjct: 1806 GHLCEREASLVVRHIARALDFLHSKGIAHRDLKPENILCEHLDDVVPVKICDFDLASGIS 1627

Query: 222  KKGE-----MLNTFCGSPPYAAPELFR----DQHYVGVYVDIWALGVLLYFMVTGTMPF- 271
              G+      L T  GS  Y APE+      D        D+W+LG++LY M+ G  PF 
Sbjct: 1626 CDGDGTKTPELLTPVGSAEYMAPEVVDAWVGDSFSYDKRCDLWSLGIILYIMLCGYPPFY 1447

Query: 272  ----------RAETVAK----LKKSILEGTYTIPQH----VSEPCHRLIRGVLQPTPTER 313
                      R E        L  SI +G Y  P      +S     LIR +L   P +R
Sbjct: 1446 GQCGEDCGWNRGEACHDCQDMLFNSIQDGHYKFPSQEWTSISSSAKDLIRHLLVREPRKR 1267

Query: 314  YGINYIMSNEWMRGVPYPTPLEPFQLDPKHLSETSTLKEEENEVKSTLEHLGITDEHI 371
            Y    ++ + W+   P  T L      P  L+  +++K+ EN  ++ +    +  +HI
Sbjct: 1266 YSAADVLKHPWICTPPAATQLAT----PHVLTRNNSMKDLENFAETAISINRMMQQHI 1105
>04591
          Length = 1117

 Score = 78.6 bits (192), Expect = 5e-15,   Method: Compositional matrix adjust.
 Identities = 48/156 (30%), Positives = 80/156 (51%), Gaps = 9/156 (5%)
 Frame = -2

Query: 120  REISSMEKLHHPNIVRLYEVVETL--------SKLHLVMEYAGGGELFGKIST-EGKLSE 170
            REI  +++L H N+V+L E+  T         S  +L+ EY    +L G ++    K S 
Sbjct: 1074 REIKILQQLEHENVVQLQEICHTQAGPYNRYKSTFYLIFEYCDY-DLAGLLNNLRVKFSL 898

Query: 171  PESKLIFSQILSAVKHMHENQIIHRDLKAENVFYTSRTCVKVGDFGFSTVSKKGEMLNTF 230
             + K + SQ+L+ + ++H  QI+HRD+KA N+  T    +K+ DFG S    K + L   
Sbjct: 897  ADKKNLMSQLLNGLFYIHTKQILHRDIKAANILLTRDGVLKLADFGLSRPWVKSKRLTNR 718

Query: 231  CGSPPYAAPELFRDQHYVGVYVDIWALGVLLYFMVT 266
              +  Y  PEL   +   G  +D+W +G ++  M +
Sbjct: 717  VVTLWYRPPELLLGEREYGPEIDMWGVGCIMAEMWS 610
>14126
          Length = 1265

 Score = 78.6 bits (192), Expect = 5e-15,   Method: Compositional matrix adjust.
 Identities = 64/223 (28%), Positives = 101/223 (45%), Gaps = 10/223 (4%)
 Frame = +3

Query: 98  EKVAIKILDKTKLDQKTQRLLSREIS---SMEKLHHPNIVRLYEVV-ETLS----KLHLV 149
           E VA+K +     ++    +  REIS    +E+  HPN+VRL +V   T++    +L+LV
Sbjct: 270 EFVAMKRIRLNNTEEGMPMMAIREISMLKQLEQYEHPNVVRLLDVSHNTITDREIRLNLV 449

Query: 150 MEYA--GGGELFGKISTEGKLSEPESKLIFSQILSAVKHMHENQIIHRDLKAENVFYTSR 207
            EY          K  + G L     K +  Q+L+ V  +H N+I+HRDLK +N+  +  
Sbjct: 450 FEYIEHDLATYLAKCPSPG-LGPDRIKDLMLQLLNGVDFLHSNRIVHRDLKPQNLLISKD 626

Query: 208 TCVKVGDFGFSTVSKKGEMLNTFCGSPPYAAPELFRDQHYVGVYVDIWALGVLLYFMVTG 267
             +K+ DFG + +      L T   +  Y +PE+     Y G  VDIW+ G +   + T 
Sbjct: 627 GRLKLADFGLARIYSFHMALTTVVVTLWYRSPEVLMQAEY-GTSVDIWSCGCIFAELFTR 803

Query: 268 TMPFRAETVAKLKKSILEGTYTIPQHVSEPCHRLIRGVLQPTP 310
              F+  +     K I E     P         + R   +PTP
Sbjct: 804 RALFKGSSEFDQLKKIFEVIGLPPAGDWPEGVSVHRNSFRPTP 932
>06405
          Length = 1965

 Score = 76.3 bits (186), Expect = 2e-14,   Method: Compositional matrix adjust.
 Identities = 54/201 (26%), Positives = 87/201 (43%), Gaps = 5/201 (2%)
 Frame = +1

Query: 76  IRGEIGSGNFSQVKLGIHSLTKEKVAIKILDKTKLDQKTQRLLSREISSMEKLHHPNIVR 135
           ++  +G G +  V   +     + VA+K L   K D         E + M+++ HPN+V+
Sbjct: 271 MKHRLGGGQYGDVYEAMWKRYNKIVAVKTL---KEDTMALNDFLEEAAIMKEMKHPNLVQ 441

Query: 136 LYEVVETLSKLHLVMEYAGGGELFGKISTEGKLSEPESKLIF--SQILSAVKHMHENQII 193
           L  V       ++V E+   G L   + +  +     + L++  +QI S + ++     I
Sbjct: 442 LLGVCTREPPFYIVTEFMPHGNLLDYLRSSTREENGPTALMYMATQIASGMAYLETKNFI 621

Query: 194 HRDLKAENVFYTSRTCVKVGDFGFSTVSKKGEMLNTFCGSPP--YAAPELFRDQHYVGVY 251
           HRDL A N        VKV DFG + + K            P  + APE      +    
Sbjct: 622 HRDLAARNCLVADSNMVKVADFGLARLMKDDTYTAHIGAKFPIKWTAPEGLAFNRF-STR 798

Query: 252 VDIWALGVLLYFMVT-GTMPF 271
            DIWA GVLL+ + T G  P+
Sbjct: 799 SDIWAFGVLLWELATYGMSPY 861
>31885
          Length = 529

 Score = 74.7 bits (182), Expect = 6e-14,   Method: Compositional matrix adjust.
 Identities = 42/164 (25%), Positives = 78/164 (47%), Gaps = 4/164 (2%)
 Frame = -2

Query: 122 ISSMEKLHHPNIVRLYEVVETLSKLHLVMEYAGGGELFGKISTEGKLSEPESKLIFSQIL 181
           +  + +L HP +V L+   +    L +V++   GG+L   +  E    E   K    Q+ 
Sbjct: 519 VDMLTRLDHPFLVNLWYAFQDEEDLFMVVDLFLGGDLRYHMQQEVSFREDCVKFYLCQLA 340

Query: 182 SAVKHMHENQIIHRDLKAENVFYTSRTCVKVGDFGFSTVSKKGEMLNTFCGSPPYAAPEL 241
             + ++   +I+HRD+K +N+    +    V DF  +T  +  E+  +  G+ PY APE+
Sbjct: 339 LVLDYLRSQKIVHRDIKPDNILLDEQGHCHVTDFNIATQLEDDELATSTSGTRPYMAPEV 160

Query: 242 F----RDQHYVGVYVDIWALGVLLYFMVTGTMPFRAETVAKLKK 281
           +     ++   G  VD W+LGV L+ ++    PF   +   L +
Sbjct: 159 YGVAINERRGYGFPVDWWSLGVSLFELLKKRRPFSVHSNTSLHE 28
>00392
          Length = 668

 Score = 74.3 bits (181), Expect = 9e-14,   Method: Compositional matrix adjust.
 Identities = 57/215 (26%), Positives = 105/215 (48%), Gaps = 12/215 (5%)
 Frame = +3

Query: 105 LDKTKLDQKTQRLLSREISSMEKLHHPNIVRLYEVVETLSK-----LHLVMEYAGGGELF 159
           L   K ++  ++    E   +++L HPNIVR ++  E  +      + LV E    G L 
Sbjct: 33  LQDKKWNKAERQRFKEEAEMLKELQHPNIVRFFDYWEEHNHRNRKVIILVTELMTSGTLK 212

Query: 160 GKISTEGKLSEPESKLIFS---QILSAVKHMHENQ--IIHRDLKAENVFYTSRT-CVKVG 213
             +    +  +P  K++ +   Q+L  +  +H     +IHRDLK +N+F T  T  VK+G
Sbjct: 213 TYLK---RFKKPNVKILKNWCRQVLKGLYFLHTRTPPVIHRDLKCDNIFITGPTGSVKIG 383

Query: 214 DFGFSTVSKKGEMLNTFCGSPPYAAPELFRDQHYVGVYVDIWALGVLLYFMVTGTMPF-R 272
           D G +T+ K      +  G+P + APE++ ++HY    VD++A G+ +  M +   P+  
Sbjct: 384 DLGLATL-KNQSFAKSVIGTPEFMAPEMY-EEHYDEA-VDVYAFGMCMLEMASSEYPYSE 554

Query: 273 AETVAKLKKSILEGTYTIPQHVSEPCHRLIRGVLQ 307
               A++ K +  G   +P+ + +     IR ++ 
Sbjct: 555 CSNAAQIYKRVTSG--VLPEALDKVAITEIRDIIH 653
>19301
          Length = 712

 Score = 73.9 bits (180), Expect = 1e-13,   Method: Compositional matrix adjust.
 Identities = 49/140 (35%), Positives = 74/140 (52%), Gaps = 1/140 (0%)
 Frame = +2

Query: 80  IGSGNFSQVKLGIHSLTKEKVAIKILDKTKLDQKTQRLLSREISSMEKLHHPNIVRLYEV 139
           +GSG    V LG   L  E+VA+K         K + +   +I ++ KL+HPNI+    V
Sbjct: 329 LGSGAQGAVFLG--KLCAEEVAVK---------KVRDIKETDIRNLRKLNHPNIISFKGV 475

Query: 140 VETLSKLHLVMEYAGGGELFGKISTEGKLSEPESKLIFS-QILSAVKHMHENQIIHRDLK 198
                   ++MEY   G+L+ ++  +GK   P   L +S QI S + ++H ++IIHRDLK
Sbjct: 476 CTQAPCYCIIMEYCPYGQLY-EVLRDGKEIPPALVLDWSKQIASGMNYLHSHKIIHRDLK 652

Query: 199 AENVFYTSRTCVKVGDFGFS 218
           + NV       VK+ DFG S
Sbjct: 653 SPNVLVAKNDVVKISDFGTS 712
>18663
          Length = 600

 Score = 70.5 bits (171), Expect = 1e-12,   Method: Compositional matrix adjust.
 Identities = 39/97 (40%), Positives = 53/97 (54%), Gaps = 9/97 (9%)
 Frame = +2

Query: 228 NTFCGSPPYAAPELFRDQHYVGVYVDIWALGVLLYFMVTGTMPFRAETVAK--------- 278
           +TFCG+P Y APE+ R + Y G  VD WALGVLLY M+ G  PF     ++         
Sbjct: 2   STFCGTPNYIAPEILRGEDY-GFSVDWWALGVLLYEMLAGRSPFDIAGASENPDQNTEDY 178

Query: 279 LKKSILEGTYTIPQHVSEPCHRLIRGVLQPTPTERYG 315
           L + ILE T  IP+ +S     +++G L   P +R G
Sbjct: 179 LFQVILEKTIRIPRSLSVKAASVLKGFLNKNPADRLG 289
>20152
          Length = 445

 Score = 70.1 bits (170), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 30/88 (34%), Positives = 49/88 (55%)
 Frame = +1

Query: 239 PELFRDQHYVGVYVDIWALGVLLYFMVTGTMPFRAETVAKLKKSILEGTYTIPQHVSEPC 298
           PE+     Y    VD+W+LGV+LY +V G  PF+    ++    I++  Y IP H+S  C
Sbjct: 1   PEILLGDSYDAPAVDVWSLGVILYMLVVGEAPFQEANDSETLTMIMDCRYQIPPHISHKC 180

Query: 299 HRLIRGVLQPTPTERYGINYIMSNEWMR 326
             LI  +LQ  P +R  + +I+++ W+ 
Sbjct: 181 QDLIEKMLQREPVDRASLPHILAHPWLN 264
>00486
          Length = 797

 Score = 69.3 bits (168), Expect = 3e-12,   Method: Compositional matrix adjust.
 Identities = 37/88 (42%), Positives = 51/88 (57%), Gaps = 1/88 (1%)
 Frame = -2

Query: 229 TFCGSPPYAAPELF-RDQHYVGVYVDIWALGVLLYFMVTGTMPFRAETVAKLKKSILEGT 287
           TFCG+  Y APE+  R  H  G  VD W+LG L+Y M+TG+ PF AE   K    IL+G 
Sbjct: 781 TFCGTIEYMAPEILTRTGH--GKAVDWWSLGALMYDMLTGSPPFTAENRKKTIDKILKGK 608

Query: 288 YTIPQHVSEPCHRLIRGVLQPTPTERYG 315
             +P +++     LI+ +L+  P ER G
Sbjct: 607 LNLPPYLTNEARGLIKKLLRKNPAERLG 524
>01060
          Length = 1800

 Score = 68.9 bits (167), Expect = 4e-12,   Method: Compositional matrix adjust.
 Identities = 53/200 (26%), Positives = 91/200 (45%), Gaps = 3/200 (1%)
 Frame = +1

Query: 79  EIGSGNFSQVKLGIHSLTKEKVAIKILDKTKLDQKTQRLLSREISSMEKLHHPNIVRLYE 138
           +IG G +  V    H  T  K+A+K +     +        REI+ + +L H NIV L +
Sbjct: 94  KIGEGTYGVVYKCRHRATGRKLAMKKIRLRGSEDGVPSSAIREIAMLRELRHTNIVCLED 273

Query: 139 VVETLSKLHLVMEYAGGG-ELFGKISTEGK-LSEPESKLIFSQILSAVKHMHENQIIHRD 196
           V+    +L LV E+     +++     EG  L     K    QI++ +   H+ +I+HRD
Sbjct: 274 VIMEDERLFLVFEFLSMDLKMYIDKFPEGVVLDRRLVKSYVFQIVTGIXFCHQRRIVHRD 453

Query: 197 LKAENVFYTSRTCVKVGDFGFS-TVSKKGEMLNTFCGSPPYAAPELFRDQHYVGVYVDIW 255
           LK +N+       +K+ DFG + T +           +  Y APE+          VD+W
Sbjct: 454 LKPQNLLINHTGAIKIADFGMARTFALPVRAYTHEVVTLWYRAPEILMGASKYSTPVDVW 633

Query: 256 ALGVLLYFMVTGTMPFRAET 275
           ++G +   M+  T  F+ ++
Sbjct: 634 SIGTIFADMLIRTPIFKGDS 693
>14477
          Length = 493

 Score = 68.2 bits (165), Expect = 6e-12,   Method: Compositional matrix adjust.
 Identities = 47/149 (31%), Positives = 74/149 (49%), Gaps = 3/149 (2%)
 Frame = -1

Query: 79  EIGSGNFSQVKLGIHSLTKEK--VAIKILDKTKLDQKTQRLLSREISSMEKLHHPNIVRL 136
           ++G+GNF  V  G+  L   +  VAIK+L    LD   Q  L +E   M+K+ H +IVRL
Sbjct: 469 KLGAGNFGSVMKGVCRLDDREIPVAIKVLKNADLDPSVQSELIKEAEVMKKMDHMHIVRL 290

Query: 137 YEVVETLSKLHLVMEYAGGGELFGKISTEGKLSEPESKLIFSQILSAVKHMHENQIIHRD 196
             + E    + LV+E A  G L   +     L       +  Q+   ++++  N+ +HRD
Sbjct: 289 IGLCEG-ETMMLVLELAKLGPLNKFLPKNKHLPLWNILELMWQVSQGMEYLEANKFVHRD 113

Query: 197 LKAENVFYTSRTCVKVGDFGFS-TVSKKG 224
           L A N+        K+ DFG S T+S++ 
Sbjct: 112 LAARNILLCDEHFAKISDFGMSKTLSREN 26
>11780
          Length = 1713

 Score = 66.2 bits (160), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 63/194 (32%), Positives = 98/194 (50%), Gaps = 10/194 (5%)
 Frame = +3

Query: 80  IGSGNFSQVKLGIHSLTKEKVAIKIL-DKTKLDQKTQRLLSREISSMEKLHHPNIVRLYE 138
           IG G+F  V  G++    + VAIK L DK   D+  Q  L +E S M  L H N+VRL  
Sbjct: 621 IGKGDFGDVYKGMYR--GQPVAIKQLKDK---DRGEQSFL-QEASVMTSLRHDNLVRLIG 782

Query: 139 VV--ETLSKLHLVMEYAGGGELFGKISTEGK--LSEPESKLIFSQILSAVKHMHENQIIH 194
           VV  ET+    LV E+ G G L   + + G+  +++ +     +   +A++++   +++H
Sbjct: 783 VVLGETI---FLVTEFMGKGNLVEYLRSRGRSVITKKDQINFATDTCAAMEYLESKRLVH 953

Query: 195 RDLKAENVFYTSRTCVKVGDFGFSTVSKKGEMLNTFCGSP-PYAAPELFRDQ--HYVGVY 251
           RDL A NV        KV DFG   ++K G+   T    P  + APE  R+   H    +
Sbjct: 954 RDLAARNVLVHDDGKAKVSDFG---LAKFGDFSQTSVKFPIKWTAPEALRENKIH*QVRH 1124

Query: 252 VDIW--ALGVLLYF 263
           V++W   +G LL +
Sbjct: 1125VELWHIVMGNLLLW 1166
>01718
          Length = 959

 Score = 65.1 bits (157), Expect = 5e-11,   Method: Compositional matrix adjust.
 Identities = 54/217 (24%), Positives = 102/217 (47%), Gaps = 14/217 (6%)
 Frame = +3

Query: 79  EIGSGNFSQVKLGIHSLTKEKVAIKILDKTKLDQKTQRLLSREISSMEKLHHPNIVRLYE 138
           +IG+G FS+V    H +T + +A+K+   T      +  + RE+  + +L H NI+R   
Sbjct: 168 KIGAGFFSEVFKVTHRITGQVMALKMNTMTS----NRHNMLREVQLLNRLQHANILRFMG 335

Query: 139 VVETLSKLHLVMEYAGGGELFGKISTEGKLSEPESKLIFSQ-------ILSAVKHMHENQ 191
           V     +LH + EY   G L      E  L + + +L ++Q       +   + ++H  +
Sbjct: 336 VCVHEGQLHALTEYIPSGNL------EQLLEKKDEELPWTQRIQLTLGLARGLDYLHSTR 497

Query: 192 IIHRDLKAENVFYTSRTC----VKVGDFGFSTV---SKKGEMLNTFCGSPPYAAPELFRD 244
            IHRDL ++N+             + DFG +T        E L T  GSP + APE+  +
Sbjct: 498 FIHRDLTSKNILIRREDNHGYHAVIADFGLATKIPDPLDKEKLPTV-GSPYWMAPEVL-N 671

Query: 245 QHYVGVYVDIWALGVLLYFMVTGTMPFRAETVAKLKK 281
            H+     D++++G+++   +T  +P   + + ++  
Sbjct: 672 GHFYNERADLFSVGIIMC-EITARIPADPDIMPRMNN 779
>27405
          Length = 532

 Score = 63.2 bits (152), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 45/161 (27%), Positives = 79/161 (49%), Gaps = 9/161 (5%)
 Frame = -3

Query: 96  TKEKVAIKILDKTKLDQK-------TQRLLSREISSMEKLHHPNIVRLYEVVETLSKLHL 148
           T +  A+K LDK ++  K        +R++   +S+ E    P IV +    +T  KL  
Sbjct: 494 TGKMYAMKCLDKKRIKMKGGETLALNERIMLSLVSTGEG--SPFIVCMTYAFQTPEKLCF 321

Query: 149 VMEYAGGGELFGKISTEGKLSEPESKLIFSQILSAVKHMHENQIIHRDLKAENVFYTSRT 208
           +++   GG+L   +S  G  +E E +   ++++  ++HMH   +++RDLK  N+      
Sbjct: 320 ILDLMNGGDLHYHLSQHGVFTEKEVRFYAAEVMLGLEHMHSRFVVYRDLKPANILLDENG 141

Query: 209 CVKVGDFGFST-VSKKGEMLNTFCGSPPYAAPE-LFRDQHY 247
            V++ D G +   SKK    +   G+  Y APE L + Q Y
Sbjct: 140 HVRISDLGLACDFSKKKPHASV--GTHGYMAPEVLMKGQAY 24
>17253
          Length = 483

 Score = 60.5 bits (145), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 39/140 (27%), Positives = 62/140 (44%), Gaps = 13/140 (9%)
 Frame = -1

Query: 92  IHSLTKEKVAIKILDKTKLDQKTQRLLSREISSMEKL-HHPNIVRLYEVVETLSKLHLVM 150
           +H+   + VA+K  ++   D +    L RE+S M KL  HPN+V             ++M
Sbjct: 483 VHARQWDTVAVKTHNEAATDAEKSEFL-RELSIMRKLPRHPNVVSFMGCCTMSDPALILM 307

Query: 151 EYAGGGELFGKI------------STEGKLSEPESKLIFSQILSAVKHMHENQIIHRDLK 198
           E+   G+L   +            ST   L+  +       +   + H+  N+I+HRD+ 
Sbjct: 306 EFCCHGDLLSFLRKRRPDRTVFLTSTANDLTARDFFSFALHVARGMAHVANNKIVHRDVA 127

Query: 199 AENVFYTSRTCVKVGDFGFS 218
           A NV  + R   KV DFG S
Sbjct: 126 ARNVLISERNVCKVSDFGLS 67
>13212
          Length = 1067

 Score = 60.5 bits (145), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 35/106 (33%), Positives = 57/106 (53%), Gaps = 6/106 (5%)
 Frame = -1

Query: 162  ISTEGKLSEPESKLIFSQILSAVKHMHENQIIHRDLKAENVFYTSRTCVKVGDFGFSTVS 221
            +  E  ++E +   +  ++  A+  +H + +IHRD+KA NV  T    VK+ DFG S  +
Sbjct: 1007 VDLEKPMTEAQICYVCHEMCMALDFLHRHHVIHRDIKAGNVLLTIDGEVKLADFGVSAKN 828

Query: 222  KKGEM-LNTFCGSPPYAAPEL-----FRDQHYVGVYVDIWALGVLL 261
             + +   +TF G+P + APE+      +D  Y     DIW+LGV L
Sbjct: 827  TQTQQKRDTFIGTPYWMAPEVVLCETLKDTPY-DFKADIWSLGVTL 693
>14116
          Length = 1017

 Score = 59.3 bits (142), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 59/242 (24%), Positives = 104/242 (42%), Gaps = 16/242 (6%)
 Frame = -1

Query: 41  QQRQLTPFEKLTQDMCQDEKVVREITLGKRIGFYRIRGEIGSGNFSQVKLGIHSLTKEK- 99
           Q  +  P   + +DM    K++   +L     F  +  EIG GNF  VK G  +L ++K 
Sbjct: 720 QGAEAMPLLHIDEDMM---KLIENESLLIDREFLTMGEEIGKGNFGCVKRGFLTLPEQKG 550

Query: 100 ---VAIKILDKTKLDQKTQRLLSREISSMEKLHHPNIVRLYEVVETLSKLHL-VMEYAGG 155
              VA+K L      +   +   +E   M+  HH N++ L  +   L  + L V+ +   
Sbjct: 549 DILVAVKTLHNNNPREIELQSFLQEALIMKDFHHSNVLTLIGICLNLDDMPLVVLPFMKH 370

Query: 156 GELFGKISTEGKLSEPESKLIFS-QILSAVKHMHENQIIHRDLKAENVFYTSRTCVKVGD 214
           G+L   I  +      +  +++   I   + ++   + +HRDL A N        VKV D
Sbjct: 369 GDLLTYIRDDQHQPTIKDLIMYGVDIARGMDYLAGLKFVHRDLAARNCMLDEDFHVKVAD 190

Query: 215 FG----------FSTVSKKGEMLNTFCGSPPYAAPELFRDQHYVGVYVDIWALGVLLYFM 264
           FG          +S+ +KK ++         + A E     +Y     D+W+ GV+L+ +
Sbjct: 189 FGLARDIYEKEYYSSENKKAKL------PVKWMALESLEKGNY-DSKTDVWSYGVVLWEL 31

Query: 265 VT 266
           +T
Sbjct: 30  LT 25
>01966
          Length = 1735

 Score = 54.7 bits (130), Expect(2) = 3e-09,   Method: Compositional matrix adjust.
 Identities = 37/128 (28%), Positives = 62/128 (48%), Gaps = 2/128 (1%)
 Frame = -1

Query: 93   HSLTKEKVAIKILDKTKLDQKTQRLLSREISSMEKLHHPNIVRLYEVVETLSKLHLVMEY 152
            H  T  K+A+K +     +        REI+ + +L H NIV L +V+    +L LV E+
Sbjct: 1648 HRATGRKLAMKKIRLRGSEDGVPSSAIREIAMLRELRHTNIVCLEDVIMEDERLFLVFEF 1469

Query: 153  AGGG-ELFGKISTEGK-LSEPESKLIFSQILSAVKHMHENQIIHRDLKAENVFYTSRTCV 210
                 +++     EG  L     K    QI++ +   H+ +I+HRDLK +N+       +
Sbjct: 1468 LSMDLKMYIDKFPEGVVLDRRLVKSYVFQIVTGINFCHQRRIVHRDLKPQNLLINHTGAI 1289

Query: 211  KVGDFGFS 218
            K+ DFG +
Sbjct: 1288 KIADFGMA 1265

 Score = 24.3 bits (51), Expect(2) = 3e-09,   Method: Compositional matrix adjust.
 Identities = 11/36 (30%), Positives = 19/36 (52%), Gaps = 3/36 (8%)
 Frame = -3

Query: 243  RDQHYVGVY---VDIWALGVLLYFMVTGTMPFRAET 275
            RD H    Y   VD+W++G +   M+  T  F+ ++
Sbjct: 1199 RDPHGASKYSTPVDVWSIGTIFADMLIRTPIFKGDS 1092
>12786
          Length = 460

 Score = 58.9 bits (141), Expect = 4e-09,   Method: Compositional matrix adjust.
 Identities = 37/121 (30%), Positives = 57/121 (47%), Gaps = 22/121 (18%)
 Frame = -3

Query: 174 KLIFSQILSAVKHMHENQIIHRDLKAENVFYTSRTCVKVGDFGFSTV---SKKGEMLNTF 230
           K  + ++L AVK +H   +IH DLK  N F      +K+ DFG +      K   + ++ 
Sbjct: 401 KFYWREMLRAVKALHNEGVIHSDLKPAN-FMLVAGNLKLIDFGIANTLQQDKTSVLKDSR 225

Query: 231 CGSPPYAAPELF-------------------RDQHYVGVYVDIWALGVLLYFMVTGTMPF 271
            G+P Y +PE                     + ++ VGV  D+W+LG +LY MV G  PF
Sbjct: 224 VGTPSYMSPEAIMAACDDSADDSMEEDGHRTKPKYKVGVRSDVWSLGCILYNMVYGRTPF 45

Query: 272 R 272
           +
Sbjct: 44  Q 42
>04852
          Length = 1462

 Score = 58.9 bits (141), Expect = 4e-09,   Method: Compositional matrix adjust.
 Identities = 55/226 (24%), Positives = 94/226 (41%), Gaps = 33/226 (14%)
 Frame = +1

Query: 100 VAIKILDKTKLDQKTQRLLSREISSMEKL----HHPNIVRLYEVVETLSKLHLVMEYAGG 155
           VA+K+L       + Q  + +E+  M+ +     H NIV           L +++E+A  
Sbjct: 28  VAVKMLRDIVTAVEEQDFV-QELQVMKAVKKMGSHINIVNFLGCCTQGGPLWVIVEFAKN 204

Query: 156 GELFG-------KISTEGKLSEPESKLIFS------------------QILSAVKHMHEN 190
           G L          I+  GK   P+    ++                  QI   ++ +   
Sbjct: 205 GNLRDFLESCRDGINGYGKFVSPQDPGWYTKTPGGHVIRRKNLLSYAFQIARGMEFLASR 384

Query: 191 QIIHRDLKAENVFYTSRTCVKVGDFGFSTVSKKGEMLNTFCGS---PPYAAPELFRDQHY 247
           + IHRDL A NV  T    +K+ DFG   +S+ G+      G      + APE   D  Y
Sbjct: 385 KCIHRDLAARNVLVTEEHVLKIADFG---LSRTGDYYKKRSGGRLPVKWMAPEALFDMRY 555

Query: 248 VGVYVDIWALGVLLYFMVT-GTMPFRAETVAKLKKSILEGTYTIPQ 292
                D+W+ GV+L+ + + G MP+ +    +L   +L+  Y +P+
Sbjct: 556 T-TKSDVWSFGVVLWEIFSLGGMPYASIPNEELYSKLLDDAYRMPR 690
>19094
          Length = 898

 Score = 58.5 bits (140), Expect = 5e-09,   Method: Compositional matrix adjust.
 Identities = 35/107 (32%), Positives = 55/107 (51%), Gaps = 5/107 (4%)
 Frame = +1

Query: 168 LSEPESKLIFSQILSAVKHMHENQIIHRDLKAENVFYTSRTCVKVGDFGFS-----TVSK 222
           L E E   I    L  + ++H  + IHRD+KA N+   +    K+ DFG +     T++K
Sbjct: 49  LVEREIATILYYTLKGL*YLHSRRKIHRDIKAGNILLNNEGHAKLADFGVAGQLTDTMAK 228

Query: 223 KGEMLNTFCGSPPYAAPELFRDQHYVGVYVDIWALGVLLYFMVTGTM 269
           +    NT  G+P + APE+ ++  Y  V  DIW+LG+    M  G +
Sbjct: 229 R----NTVIGTPYWMAPEVIQEIGYDCV-ADIWSLGITALEMAEGNL 354
>26711
          Length = 405

 Score = 58.2 bits (139), Expect = 6e-09,   Method: Composition-based stats.
 Identities = 33/112 (29%), Positives = 60/112 (53%), Gaps = 5/112 (4%)
 Frame = -2

Query: 176 IFSQILSAVKHMHENQIIHRDLKAENVFYTSRT--CVKVGDFGFST--VSKKGEMLNTFC 231
           +  Q+L  ++H+H   ++H DLK  N+  +      V++ DFG +      +   LN   
Sbjct: 401 VVKQVLDILQHVHAQGVVHMDLKPSNLLLSGDKLDSVQLIDFGLARKLYPPQETFLNH-- 228

Query: 232 GSPPYAAPELFRDQHYVGVYVDIWALGVLLYFMVTGTMPFRAETVAK-LKKS 282
           G+P + +PE   D   +    D+W +GVL Y +++G  PF+A++  + LKK+
Sbjct: 227 GTPGFTSPEAL-DVKPISTASDVWGVGVLAYILLSGQSPFQADSATESLKKT 75
>29590
          Length = 320

 Score = 57.0 bits (136), Expect = 2e-08,   Method: Composition-based stats.
 Identities = 33/100 (33%), Positives = 49/100 (49%)
 Frame = +3

Query: 214 DFGFSTVSKKGEMLNTFCGSPPYAAPELFRDQHYVGVYVDIWALGVLLYFMVTGTMPFRA 273
           D GF+ ++  GE +    G+P Y APE+  D   + +  D+W+LGVL Y M+T   PF  
Sbjct: 6   DLGFACLTNTGEDIRDIIGTPDYVAPEVL-DYEPLSIQTDMWSLGVLSYVMLTACSPFVG 182

Query: 274 ETVAKLKKSILEGTYTIPQHVSEPCHRLIRGVLQPTPTER 313
            T  K   + L   +T  Q +S      +  VL P  + R
Sbjct: 183 ITSKKHSATSLRSNWT-SQMISS-----LTSVLMPKTSSR 284
>26560
          Length = 398

 Score = 56.6 bits (135), Expect = 2e-08,   Method: Composition-based stats.
 Identities = 32/117 (27%), Positives = 57/117 (48%), Gaps = 1/117 (0%)
 Frame = -1

Query: 157 ELFGKISTEGKLSEPESKLIFSQILSAVKHMHENQIIHRDLKAENVFYTSRTCVKVGDFG 216
           +L   +S  G  +E E +   ++++  ++HMH   +++RDLK  N+       V++ D G
Sbjct: 398 DLHYHLSQHGVFTEKEVRFYAAEVMLGLEHMHSRFVVYRDLKPANILLDENGHVRISDLG 219

Query: 217 FST-VSKKGEMLNTFCGSPPYAAPELFRDQHYVGVYVDIWALGVLLYFMVTGTMPFR 272
            +   SKK    +   G+  Y APE+           D ++ G +LY ++ G  PFR
Sbjct: 218 LACDFSKKRPHASV--GTHGYMAPEVLMKGQSYDSSADWFSFGCMLYKLLKGHSPFR 54
>37602
          Length = 804

 Score = 55.8 bits (133), Expect = 4e-08,   Method: Compositional matrix adjust.
 Identities = 31/96 (32%), Positives = 44/96 (45%), Gaps = 6/96 (6%)
 Frame = -1

Query: 145 KLHLVMEYAGGGELFGKISTEGKLSEPESKLIFSQILSAVKHMHENQIIHRDLKAENVFY 204
           KL + MEY GGG +       G L+EP+   +  + L  + ++H    +HRD+K  N+  
Sbjct: 297 KLWIAMEYCGGGSMQDIYHVTGPLTEPQIAFVCRETLKGLHYLHRRGKMHRDIKGANILL 118

Query: 205 TSRTCVKVGDFG------FSTVSKKGEMLNTFCGSP 234
           T    VK+ DF          V KK    N F G P
Sbjct: 117 TEEGDVKLADFWRVSSNHSHNVQKKVFHWNAFIGWP 10
>19761
          Length = 473

 Score = 55.1 bits (131), Expect = 5e-08,   Method: Compositional matrix adjust.
 Identities = 29/87 (33%), Positives = 49/87 (56%), Gaps = 3/87 (3%)
 Frame = -3

Query: 179 QILSAVKHMHENQ--IIHRDLKAENVFYTSRTCVKVGDFGFS-TVSKKGEMLNTFCGSPP 235
           Q  SA+ +MH +   I+HRDLK +N++ T +  V++GD G +  ++   +   +  G+  
Sbjct: 399 QTASALNYMHTHTPVILHRDLKPQNIYVTEKGDVRLGDLGLARKLTGPADFATSQVGTIM 220

Query: 236 YAAPELFRDQHYVGVYVDIWALGVLLY 262
           Y +PE+   Q Y     DIW+LG + Y
Sbjct: 219 YLSPEILSQQPY-NSKSDIWSLGCVFY 142
>07940
          Length = 1336

 Score = 50.4 bits (119), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 35/118 (29%), Positives = 59/118 (50%), Gaps = 5/118 (4%)
 Frame = -3

Query: 167 KLSEPESKLIFS-QILSAVKHMHENQIIHRDLKAENVFYTSRTCVKVGDFGFSTVSKKGE 225
           K+  P+  + ++ Q+   ++++   Q IHRDL A NV       +K+ DFG +   ++ +
Sbjct: 362 KMLTPKDLISYAYQVARGMEYLASKQCIHRDLAARNVLVAEEYVLKIADFGLTRNLQQFD 183

Query: 226 ML-NTFCGSPP--YAAPELFRDQHYVGVYVDIWALGVLLYFMVT-GTMPFRAETVAKL 279
               T  G  P  + APE   D+ Y     D+W+ GVLL+ + T G  P+ +  V  L
Sbjct: 182 YYRKTTDGRLPVKWMAPEALFDRKYTS-KSDVWSYGVLLWEIFTLGGNPYPSVPVEDL 12
>07291
          Length = 833

 Score = 49.7 bits (117), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 37/142 (26%), Positives = 66/142 (46%), Gaps = 7/142 (4%)
 Frame = +1

Query: 179 QILSAVKHMHENQIIHRDLKAENVFYTSRTCVKVGDFGFSTVSKKGEMLNTFCGSPP--- 235
           QI   + ++ E +++HR+L A N   T    +++ D+G  T S   +   T   SP    
Sbjct: 73  QIADGMAYLQEVKVVHRNLAARNCIVTEDGRLQLSDYGV-TGSLFPQSYYTADDSPARDL 249

Query: 236 --YAAPELFRDQHYVGVYVDIWALGVLLYFMVT-GTMPFRAETVAKLKKSILEG-TYTIP 291
             + APE   + H+     D+WA GV+L+ ++T G  P+     + L   + EG     P
Sbjct: 250 VKWMAPETIDNFHF-SSKSDVWAFGVVLWELLTRGITPYPDVENSSLLPYLKEGHRMKKP 426

Query: 292 QHVSEPCHRLIRGVLQPTPTER 313
           +   EP + ++      +P +R
Sbjct: 427 KQSPEPVYEMMTACWNESPEQR 492
>12672
          Length = 773

 Score = 49.3 bits (116), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 28/92 (30%), Positives = 47/92 (51%), Gaps = 6/92 (6%)
 Frame = +3

Query: 182 SAVKHMHENQIIHRDLKAENVFYTSRTCVKVGDFGFSTVSKKGE-----MLNTFCGSPPY 236
           S ++++++N  +HRD+K  N+   S    KVGDF     +  GE       +   G+  Y
Sbjct: 24  SGIQYLNDNGHVHRDIKTANILLDSEYTAKVGDFATVVSAPSGEGKTVQNASVVIGTAAY 203

Query: 237 AAPELFRDQHY-VGVYVDIWALGVLLYFMVTG 267
            APE     H+ V   +D ++ GV+L  ++TG
Sbjct: 204 LAPEAI---HFDVSTKLDSYSFGVVLLEVITG 290
>31120
          Length = 439

 Score = 48.9 bits (115), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 23/86 (26%), Positives = 43/86 (50%), Gaps = 4/86 (4%)
 Frame = +1

Query: 252 VDIWALGVLLYFMVTGTMPFRAETVAKLKKSILEGTYT----IPQHVSEPCHRLIRGVLQ 307
            D W+LGV+L+ M+ G MPF    + KL +      Y+    +   VS      +  +L+
Sbjct: 37  ADAWSLGVILFIMLNGKMPFDDSNLNKLLEDQRSKKYSFRRKLQDLVSPNARSTVSVLLE 216

Query: 308 PTPTERYGINYIMSNEWMRGVPYPTP 333
           P    R+ +N +++ +W++ +  P P
Sbjct: 217 PNSAMRWDLNEVLNCQWLQTIDEPRP 294
>04138
          Length = 800

 Score = 47.8 bits (112), Expect = 9e-06,   Method: Compositional matrix adjust.
 Identities = 25/85 (29%), Positives = 40/85 (47%), Gaps = 4/85 (4%)
 Frame = +1

Query: 186 HMHENQIIHRDLKAENVFYTSRTCVKVGDFG----FSTVSKKGEMLNTFCGSPPYAAPEL 241
           ++H N+I+HRD+KA N+  T +  +K+ DFG    FS   ++         +  Y  PEL
Sbjct: 58  YIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRVVTLWYRPPEL 237

Query: 242 FRDQHYVGVYVDIWALGVLLYFMVT 266
                     +D W  G ++  M T
Sbjct: 238 LLGDRNYSTAIDQWGAGCIMAEMWT 312
>28157
          Length = 400

 Score = 47.8 bits (112), Expect = 9e-06,   Method: Composition-based stats.
 Identities = 36/126 (28%), Positives = 63/126 (50%), Gaps = 7/126 (5%)
 Frame = +3

Query: 98  EKVAIKILDKTKLDQKTQRLLSREISSMEKLHHPNIVRLYEVVETLSKLHLVMEYAGGGE 157
           + VA+K ++     ++ ++   +E+  + ++ HPNIV LY        + LVMEYA GG 
Sbjct: 3   KDVAVKRIES----EQEKKSFMQELKQLSRVSHPNIVCLYGACRD-HPVCLVMEYAEGGS 167

Query: 158 LFGKISTEGKLSEPESKLIFSQILS---AVKHMH---ENQIIHRDLKAENVFYTS-RTCV 210
           L+  +   G   +  +    + +L     V+++H      +IHRDLK  N+      T +
Sbjct: 168 LYNVLHGSGPQPQYTAAHAMNWLLQCALGVEYLHGMKPKALIHRDLKPPNLLLIQCGTKL 347

Query: 211 KVGDFG 216
           K+ DFG
Sbjct: 348 KICDFG 365
>28638
          Length = 1458

 Score = 46.6 bits (109), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 30/85 (35%), Positives = 46/85 (54%), Gaps = 2/85 (2%)
 Frame = -1

Query: 189 ENQIIHRDLKAENVFYTS--RTCVKVGDFGFSTVSKKGEMLNTFCGSPPYAAPELFRDQH 246
           E  IIH DLK EN+   +  R+ +K+ DFG S   + G+ +  +  S  Y +PE+     
Sbjct: 777 EMNIIHCDLKPENILLCNPKRSAIKIVDFGSS--CQLGQRIYQYIQSRFYRSPEVLLGVP 604

Query: 247 YVGVYVDIWALGVLLYFMVTGTMPF 271
           Y  + +D+W+LG +L  M TG  P 
Sbjct: 603 Y-DLAIDMWSLGCILVEMHTGEPPL 532
>11185
          Length = 473

 Score = 46.2 bits (108), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 29/113 (25%), Positives = 49/113 (43%), Gaps = 23/113 (20%)
 Frame = +1

Query: 179 QILSAVKHMHENQIIHRDLKAENVFYTSRTCVKVGDFGFSTV------------SKKGEM 226
            +++ + ++H   I+  DL+   V   +   +K  DFG S V            ++ G+ 
Sbjct: 25  HLVTGLHYIHSLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEAGDQ 204

Query: 227 LNT-----------FCGSPPYAAPELFRDQHYVGVYVDIWALGVLLYFMVTGT 268
            N              GSP Y APE+F+      +  D+WALG + Y M +G+
Sbjct: 205 WNIQSAEEMMKQVPTSGSPTYMAPEVFQGAE-PSIMSDLWALGCVFYEMFSGS 360
>00715
          Length = 1788

 Score = 45.8 bits (107), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 49/205 (23%), Positives = 80/205 (39%), Gaps = 33/205 (16%)
 Frame = +1

Query: 100 VAIKILDKTKLDQKTQRL-LSREISSME-KLHHPNIVRLYEVVETLSKLH-------LVM 150
           VA+KI  K   + +  R   S E+ +    L H N+V +       + LH       L M
Sbjct: 7   VAVKIYHKRSSNPRALRQSYSNELLAFRCGLRHVNVVSILGA----TSLHRFEDGAWLAM 174

Query: 151 EYAGGGELFGKISTEGKLSEPESKLIFS-QILSAVKHMHENQIIHRDLKAENVFYTSRTC 209
           EY G   L   ++   +  +   +L  + Q+   + ++H   I+H DLK  N   T    
Sbjct: 175 EYVGPLNLQTILNDHQQDIDSSMRLSLALQMARGLHYLHSINIVHLDLKPANCLLTRDLK 354

Query: 210 VKVGDFG-----------------------FSTVSKKGEMLNTFCGSPPYAAPELFRDQH 246
           +++ DFG                             +G   N   G+  Y APEL +   
Sbjct: 355 LRIADFGCCHQLTPTGLDMGEREGGMAGNELELTPVQGAWKNELAGTLAYRAPELLKGLQ 534

Query: 247 YVGVYVDIWALGVLLYFMVTGTMPF 271
              V  D+++LG+ L+ M T   P+
Sbjct: 535 -PSVRSDVYSLGITLWQMCTRQGPY 606
>03508
          Length = 1463

 Score = 44.3 bits (103), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 26/108 (24%), Positives = 47/108 (43%), Gaps = 1/108 (0%)
 Frame = +1

Query: 168 LSEPESKLIFSQILSAVKHMHENQIIHRDLKAENVFYTSRTC-VKVGDFGFSTVSKKGEM 226
            ++ + +    +++ A+   H   I+HRD+K  NV        +++ D+G +     G  
Sbjct: 862 FTDYDIRFYLYELMKALDFCHSMGIMHRDVKPHNVMIDHENKKLRLIDWGLAEFYHPGME 1041

Query: 227 LNTFCGSPPYAAPELFRDQHYVGVYVDIWALGVLLYFMVTGTMPFRAE 274
            N    S  +  PEL  D       +D+W+LG +       +M FR E
Sbjct: 1042YNVRVASRYFKGPELLLDYQMYDYSLDMWSLGCMF-----ASMIFRKE 1170
>17300
          Length = 480

 Score = 43.5 bits (101), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 33/121 (27%), Positives = 56/121 (46%), Gaps = 7/121 (5%)
 Frame = +1

Query: 180 ILSAVKHMHENQIIHRDLKAENVFYTSRTCVKVGDFGFS----TVSKKGEMLNTFCGSPP 235
           I S +  + +   +HRDL A N+        KV DFG S    + + +G    T  G  P
Sbjct: 1   ISSGMGXLADMGYVHRDLAARNILVNEILVCKVADFGLSREIESDTTEG-AYTTKGGKIP 177

Query: 236 --YAAPELFRDQHYVGVYVDIWALGVLLY-FMVTGTMPFRAETVAKLKKSILEGTYTIPQ 292
             + APE    + +     D+W+ GV+++  M  G  P+   +   + K++ +G Y +P 
Sbjct: 178 VRWTAPEAIAYRKFTSA-SDVWSFGVVMWEVMSYGERPYWNWSNQDVIKAVEKG-YRLPL 351

Query: 293 H 293
           H
Sbjct: 352 H 354
>18996
          Length = 491

 Score = 41.6 bits (96), Expect = 6e-04,   Method: Compositional matrix adjust.
 Identities = 27/82 (32%), Positives = 40/82 (48%), Gaps = 4/82 (4%)
 Frame = +2

Query: 193 IHRDLKAENVFYTSRTCVKVGDFGFSTVSK-KGEMLNTFCGSPP--YAAPELFRDQHYVG 249
           IHRDL A N+    R+CVK+ DFG +  +   G          P  + +PE      +  
Sbjct: 2   IHRDLAARNIL-VDRSCVKISDFGLAQFANADGYYYGISQRDIPIKWYSPEAIETCKF-S 175

Query: 250 VYVDIWALGVLLYFMVT-GTMP 270
            Y D+W+ GV L+ M + G +P
Sbjct: 176 SYSDVWSYGVTLFEMFSRGEIP 241
>17722
          Length = 680

 Score = 41.6 bits (96), Expect = 6e-04,   Method: Compositional matrix adjust.
 Identities = 22/64 (34%), Positives = 32/64 (50%)
 Frame = -3

Query: 252 VDIWALGVLLYFMVTGTMPFRAETVAKLKKSILEGTYTIPQHVSEPCHRLIRGVLQPTPT 311
           VD W  GV++Y M+ G +PF       L + IL      P+++SE    L+ G+L   P 
Sbjct: 678 VDWWGTGVVMYEMMCGRLPFYNRDHDVLFELILLQNVKFPRNLSEEAKTLLSGLLAKNPK 499

Query: 312 ERYG 315
            R G
Sbjct: 498 RRLG 487
>26009
          Length = 886

 Score = 40.8 bits (94), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 15/32 (46%), Positives = 23/32 (71%)
 Frame = +3

Query: 172 ESKLIFSQILSAVKHMHENQIIHRDLKAENVF 203
           E+K +  Q++SA+  MH  Q++HRD+K ENV 
Sbjct: 714 EAKSVMKQLVSALDFMHSKQLVHRDIKPENVL 809
>07833
          Length = 1504

 Score = 40.8 bits (94), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 51/221 (23%), Positives = 98/221 (44%), Gaps = 12/221 (5%)
 Frame = -3

Query: 112  QKTQRLLSREISSMEKLHHPNIVRLYEVVETLSKLHLVMEYAGGGELFGKISTE-GKLSE 170
            ++  R    E   +   +HPN++ +         L L+ ++   G L+  +  E G + +
Sbjct: 1496 KRITRDFMEEFPRLRIFNHPNVLPVLACCNQPPNLVLISQFMPFGSLYNTLHGESGIVVD 1317

Query: 171  PESKLIFS-QILSAVKHMH--ENQIIHRDLKAENVF----YTSRTCVKVGDFGFSTVSKK 223
                L F+  I   ++ +H  E  I +  L +++V      T+R  + + D+ FS   +K
Sbjct: 1316 QNQSLRFAMDIARGMEFLHSMEPTIPNFLLTSKHVMIDEDLTAR--INMADYCFS-FHEK 1146

Query: 224  GEMLNTFCGSPPYAAPELF--RDQHYVGVYVDIWALGVLLYFMVTGTMPFRAETVAKL-K 280
            G++      SP + APE    R         D+W+  +L++ + T  +PF   +  ++  
Sbjct: 1145 GKVY-----SPAWMAPEALQRRPDDINTRAADMWSFAILMWELETREVPFAELSSMEVGM 981

Query: 281  KSILEGT-YTIPQHVSEPCHRLIRGVLQPTPTERYGINYIM 320
            K  LEG   +IP  +S    RLI+  +   P +R   + I+
Sbjct: 980  KVALEGLRISIPPGISLHMSRLIKICMNEEPGKRPRFDMII 858
>36481
          Length = 806

 Score = 40.4 bits (93), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 35/133 (26%), Positives = 60/133 (45%), Gaps = 7/133 (5%)
 Frame = +2

Query: 81  GSGNFSQVKLGIHSLTKEKVAIKILDKTKLDQKTQRLLSREISSMEKLHHPNIVRLYEVV 140
           G G F +V      L  + +A+KI+      ++  +L   EI+ +EKL   +    +  V
Sbjct: 389 GEGTFGKVVQCKDLLKGDDIALKIIKNVDKYREAAKL---EINVLEKLREKDPHAKHMCV 559

Query: 141 ETLSKL----HLVMEYAGGGEL---FGKISTEGKLSEPESKLIFSQILSAVKHMHENQII 193
           + L       H+ + +   G     F K ++ G     + + I  Q+  AV  +HENQ+ 
Sbjct: 560 QMLDWFDYHGHVCISFHMLGLSVFDFLKDNSYGAYPIEQVRHISYQLCYAVNFLHENQLT 739

Query: 194 HRDLKAENVFYTS 206
           H DLK EN+ +  
Sbjct: 740 HTDLKPENILFVD 778
>32957
          Length = 645

 Score = 40.0 bits (92), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 20/44 (45%), Positives = 25/44 (56%)
 Frame = +3

Query: 219 TVSKKGEMLNTFCGSPPYAAPELFRDQHYVGVYVDIWALGVLLY 262
            V K G    TFCG+  Y APE+   + Y G  VD W LG+LL+
Sbjct: 12  CVEKSGGRTRTFCGTREYMAPEVHERKEY-GKEVDWWGLGILLH 140
>16708
          Length = 1397

 Score = 39.3 bits (90), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 16/47 (34%), Positives = 29/47 (61%)
 Frame = -1

Query: 176  IFSQILSAVKHMHENQIIHRDLKAENVFYTSRTCVKVGDFGFSTVSK 222
            I  Q + A++H+HE  ++H D+KA+NV   +    K+ D+G + + K
Sbjct: 1079 IAGQXVCALEHIHELGVVHMDVKADNVLVDAHGNCKLTDYGIAQLYK 939
>25019
          Length = 730

 Score = 39.3 bits (90), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 26/63 (41%), Positives = 33/63 (52%), Gaps = 2/63 (3%)
 Frame = +3

Query: 198 KAENVFYTSRTCVKVGDFGFSTVSKKG-EMLNTFCGSPPYAAPELF-RDQHYVGVYVDIW 255
            AENV       VK+ DFG    +  G  + +TFCG+  Y APE+  R  H  G  VD W
Sbjct: 255 AAENVLLDKDGHVKLTDFGLCKEAITGTRVTHTFCGTIEYMAPEILTRTGH--GKAVDWW 428

Query: 256 ALG 258
           +LG
Sbjct: 429 SLG 437
>17806
          Length = 433

 Score = 38.1 bits (87), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 28/88 (31%), Positives = 45/88 (51%), Gaps = 8/88 (9%)
 Frame = +1

Query: 79  EIGSGNFSQVKLGIHS--------LTKEKVAIKILDKTKLDQKTQRLLSREISSMEKLHH 130
           E+G+G F +V   I S        +++ KV +K+L K    +  Q L   E++   +L H
Sbjct: 70  ELGTGWFGKV---IESDAERITTGVSRSKVVVKML-KDDATKDEQLLFFEEVAPFRELDH 237

Query: 131 PNIVRLYEVVETLSKLHLVMEYAGGGEL 158
           PNIVRL      ++ + ++ME A  G L
Sbjct: 238 PNIVRLLGQCTEMNPMLMLMECAALGNL 321
>08294
          Length = 1849

 Score = 38.1 bits (87), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 40/172 (23%), Positives = 66/172 (38%), Gaps = 19/172 (11%)
 Frame = +2

Query: 131  PNIVRLYEVVETLSKLHLVMEYAGGGEL------------FGKISTEGKLSEPESKLIFS 178
            PNIV    V        L+ EY   G+L             G+ +    L+  +   +  
Sbjct: 887  PNIVHFMGVCREAEPHFLITEYCDWGDLKQFLLATRNDNGRGRGTRVPALALSQKLGMGQ 1066

Query: 179  QILSAVKHMHENQIIHRDLKAENVFYTSRTCVKV------GDFGFSTVSKKGEMLNTFCG 232
            Q+ + ++ +    ++H DL A NV  TSR  +KV      GD   S      + L     
Sbjct: 1067 QVAAGMEALSNQGLVHGDLAARNVLLTSRMQLKVARPALSGDVYASEYYPLHQRLVPLRW 1246

Query: 233  SPPYAAPELFRDQHYVGVYVDIWALGVLLY-FMVTGTMPFRAETVAKLKKSI 283
             PP    E            D+WA GV L+  +    +P+R  +  ++ +S+
Sbjct: 1247 LPPEGVLE-----DSATTCGDVWAFGVFLWEVLQLADLPYRLMSDEEVLRSL 1387
>28865
          Length = 342

 Score = 38.1 bits (87), Expect = 0.007,   Method: Composition-based stats.
 Identities = 30/112 (26%), Positives = 51/112 (45%)
 Frame = -3

Query: 15  HCDRWERRDSVESSCQTEGGKDSEEDQQRQLTPFEKLTQDMCQDEKVVREITLGKRIGFY 74
           H ++  R+  +  + Q+   KD+E     + TP +K   D+ Q  ++  E  LG      
Sbjct: 331 HWEQALRQALMPITPQSSNAKDNENVTANEDTPADKQV-DISQLYQIFPEDVLG------ 173

Query: 75  RIRGEIGSGNFSQVKLGIHSLTKEKVAIKILDKTKLDQKTQRLLSREISSME 126
                  SG F  V  G H  T  +VAIK++DK +   K +  L  E++ ++
Sbjct: 172 -------SGQFGIVYGGCHRRTNREVAIKVIDKLRFPTKQEAQLKTEVAILQ 38
>00394
          Length = 548

 Score = 38.1 bits (87), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 21/69 (30%), Positives = 34/69 (49%)
 Frame = -2

Query: 73  FYRIRGEIGSGNFSQVKLGIHSLTKEKVAIKILDKTKLDQKTQRLLSREISSMEKLHHPN 132
           F +   EIG G+F  V  G+ +     VA   L   K ++  ++    E   +++L HPN
Sbjct: 295 FLKFDKEIGRGSFKTVYKGLDTELGVAVAWCELQDKKWNKAERQRFKEEAEMLKELQHPN 116

Query: 133 IVRLYEVVE 141
           IVR ++  E
Sbjct: 115 IVRFFDYWE 89
>32357
          Length = 625

 Score = 37.4 bits (85), Expect = 0.011,   Method: Compositional matrix adjust.
 Identities = 15/33 (45%), Positives = 26/33 (78%)
 Frame = -2

Query: 72  GFYRIRGEIGSGNFSQVKLGIHSLTKEKVAIKI 104
           G YR+  +IGSG+F ++ LG+H+ + E+VA+K+
Sbjct: 438 GKYRLMKKIGSGSFGEIYLGVHNTSGEEVAVKL 340
>22005
          Length = 873

 Score = 37.4 bits (85), Expect = 0.012,   Method: Compositional matrix adjust.
 Identities = 30/90 (33%), Positives = 43/90 (47%), Gaps = 10/90 (11%)
 Frame = +1

Query: 79  EIGSGNFSQVK----LGIHSLTKEKVAIK---ILDKTKLDQKTQRLLS---REISSMEKL 128
           +IG G F +V     LG+ SL  E +  K   +L K   +  ++ L S   RE S M   
Sbjct: 4   DIGQGAFGRVSKLKFLGLASLVGELIPEKRP*LL*KMLKEDASEDLQSDFEREASLMADF 183

Query: 129 HHPNIVRLYEVVETLSKLHLVMEYAGGGEL 158
            HPNIV+L  V      + L+ E+   G+L
Sbjct: 184 DHPNIVKLLGVCAIGKPMCLLFEFMSKGDL 273
>31789
          Length = 676

 Score = 37.0 bits (84), Expect = 0.017,   Method: Compositional matrix adjust.
 Identities = 21/69 (30%), Positives = 34/69 (49%)
 Frame = +2

Query: 73  FYRIRGEIGSGNFSQVKLGIHSLTKEKVAIKILDKTKLDQKTQRLLSREISSMEKLHHPN 132
           F +   EIG G+F  V  G+ +     VA   L   K ++  ++    E   +++L HPN
Sbjct: 323 FLKFDVEIGRGSFKTVYKGLDTELGVAVAWCELQDKKWNKTERQRFKEEAEMLKELQHPN 502

Query: 133 IVRLYEVVE 141
           IVR ++  E
Sbjct: 503 IVRFFDYWE 529
>31489
          Length = 329

 Score = 37.0 bits (84), Expect = 0.018,   Method: Compositional matrix adjust.
 Identities = 22/88 (25%), Positives = 43/88 (48%), Gaps = 6/88 (6%)
 Frame = +3

Query: 122 ISSMEKLHHPNIVRLYEVVE------TLSKLHLVMEYAGGGELFGKISTEGKLSEPESKL 175
           I  ++   H NI+ + E+++          +H+V +     +L   I ++  L+E   + 
Sbjct: 3   IKILKHFKHDNIISIREILKPKDSYHDFKDIHVVFD-LMESDLHRIIYSDQPLTEEHIRY 179

Query: 176 IFSQILSAVKHMHENQIIHRDLKAENVF 203
              QIL  +K++H   ++HRDLK  N+ 
Sbjct: 180 FLYQILRGLKYIHSANVVHRDLKPSNLL 263
>13840
          Length = 446

 Score = 36.6 bits (83), Expect = 0.019,   Method: Compositional matrix adjust.
 Identities = 35/125 (28%), Positives = 59/125 (47%), Gaps = 5/125 (4%)
 Frame = -1

Query: 78  GEIGSGNFSQVKLGIHSLTKEKVAIKILDKTKLDQKTQRLLSREISSMEKLHHPNIVRLY 137
           GEIG GN+  V    H +T   +A+K +  T  +++ ++LL      M   + P IV+ Y
Sbjct: 377 GEIGRGNYGTVNKMRHKITSTVMAVKRIRSTVEEREQKQLLMDLDVVMRSNNCPFIVQFY 198

Query: 138 EVVETLSKLHLVMEY--AGGGELFGKISTEGKLSEPESKL--IFSQILSAVKHMHEN-QI 192
             +       + ME       + +  +  E + S PE+ L  I    L A+ ++ E  +I
Sbjct: 197 GALFKEGDCWICMELMETSLDKFYKFVYGEMQSSIPENILGKITVATLKALNYLKEELRI 18

Query: 193 IHRDL 197
           IHRD+
Sbjct: 17  IHRDV 3
>20655
          Length = 1181

 Score = 36.6 bits (83), Expect = 0.023,   Method: Compositional matrix adjust.
 Identities = 23/63 (36%), Positives = 33/63 (52%), Gaps = 7/63 (11%)
 Frame = +2

Query: 279 LKKSILEGTYTIPQ----HVSEPCHRLIRGVLQPTPTERYGINYIMSNEWMRG---VPYP 331
           +KK I  G Y  P+     VS+    LIRG+L   P +R  I  +M+++W+     VP  
Sbjct: 2   MKKRIRNGQYEFPKPEWSRVSQDAKDLIRGMLCTDPDKRLNIKQVMASKWVADNTMVPQ- 178

Query: 332 TPL 334
           TPL
Sbjct: 179 TPL 187
>18481
          Length = 437

 Score = 36.2 bits (82), Expect = 0.025,   Method: Compositional matrix adjust.
 Identities = 39/134 (29%), Positives = 63/134 (47%), Gaps = 6/134 (4%)
 Frame = -1

Query: 91  GIHSLTKEKVAIKILDKTKLDQKTQRLLSREISSMEKL-HHPNIVRLYEVVETLSKLHLV 149
           G ++   + +A+KI     +D K Q LL  E    E++  HP +  +Y          LV
Sbjct: 428 GYNTQDGKDIAVKI---EAIDVKHQ-LLHYEAKVYEQIGRHPGLPTMYHYGTEKHFNALV 261

Query: 150 MEYAGGG--ELFGKISTEGKLSEPESKLIFSQILSAVKHMHENQIIHRDLKAENVFY-TS 206
           ME  G    ELF  +  + + +     ++  Q+LS ++ +H+   IHRDLK +N      
Sbjct: 260 MELLGPSLEELF--VICKRRFTLKTILMVSDQLLSRLEFIHQKCFIHRDLKPDNFLMGLG 87

Query: 207 RTC--VKVGDFGFS 218
           R C  + + DFG S
Sbjct: 86  RHCHRLYIIDFGLS 45
>27274
          Length = 396

 Score = 36.2 bits (82), Expect = 0.026,   Method: Composition-based stats.
 Identities = 16/35 (45%), Positives = 25/35 (71%)
 Frame = -1

Query: 240 ELFRDQHYVGVYVDIWALGVLLYFMVTGTMPFRAE 274
           EL R Q + G  VD+W+LG+LL+ +++G +PF  E
Sbjct: 375 ELLRGQQH-GPTVDMWSLGILLHELLSGHVPFEPE 274
>01106
          Length = 878

 Score = 35.8 bits (81), Expect = 0.038,   Method: Compositional matrix adjust.
 Identities = 39/144 (27%), Positives = 64/144 (44%), Gaps = 12/144 (8%)
 Frame = +3

Query: 72  GFYRIRGEIGSGNFSQVKLGIHSLTKEKVAIKILD------KTKLDQKTQRLLSREISSM 125
           G Y +  ++G G+FS V L      K  VA+K++       +T LD+       RE S +
Sbjct: 318 GRYHVIRKLGWGHFSTVWLCWDLTCKRFVALKVVKSAQHYTETALDEVKLLKCVRE-SDV 494

Query: 126 EKLHHPNIVRLYE--VVETLSKLHLVMEYAGGGELFGKI---STEGKLSEPESKLIFSQI 180
                   V+L +   +  ++  H+ M +   G    K+   S    +     KLI  Q+
Sbjct: 495 ADPARAKCVQLLDDFKISGVNGTHVAMVFEVLGYNLLKLIIRSNYQGIPIHNVKLIIRQV 674

Query: 181 LSAVKHMHEN-QIIHRDLKAENVF 203
           L  + +MH   +IIH D+K EN+ 
Sbjct: 675 LEGLSYMHAKCRIIHTDIKPENIL 746
>20559
          Length = 430

 Score = 35.4 bits (80), Expect = 0.043,   Method: Compositional matrix adjust.
 Identities = 27/75 (36%), Positives = 42/75 (56%), Gaps = 3/75 (4%)
 Frame = -2

Query: 79  EIGSGNFSQVKLGIHSLTKEKVAIKILDKTKLDQKTQRLLS---REISSMEKLHHPNIVR 135
           +IG G +  V    +  T E VA+K   + +LD   + + S   REI  +++L H NIVR
Sbjct: 354 KIGEGTYGTVFKAKNRETHEIVALK---RVRLDDDDEGVPSSALREICLLKELKHRNIVR 184

Query: 136 LYEVVETLSKLHLVM 150
           L++V+ +  KL LV 
Sbjct: 183 LHDVLHSERKLTLVF 139
>20640
          Length = 1492

 Score = 35.0 bits (79), Expect = 0.062,   Method: Compositional matrix adjust.
 Identities = 28/128 (21%), Positives = 51/128 (39%), Gaps = 7/128 (5%)
 Frame = +1

Query: 193 IHRDLKAENVFYTSRTCVKVGDFGFSTVSKKGEMLNTFCGSPPYAAPELFRDQHYV---- 248
           +HRDL   N        VK+ DFG   +++    ++ + GS   A P  +     +    
Sbjct: 10  VHRDLATRNCLVGHDLVVKISDFG---LARSVHSVDYYRGSEHDAIPIRWMPLEAILYNK 180

Query: 249 -GVYVDIWALGVLLY-FMVTGTMPFRAETVAKLKKSILEG-TYTIPQHVSEPCHRLIRGV 305
                D+W+ GV+L+        P+   T  ++ + + EG     P+    P + L++  
Sbjct: 181 FSTQSDVWSFGVVLWEIFAFALQPYYGLTHEEVVRFVKEGKVLACPERTPPPMYELMKQC 360

Query: 306 LQPTPTER 313
               P  R
Sbjct: 361 WHRRPATR 384
>21210
          Length = 518

 Score = 34.3 bits (77), Expect = 0.11,   Method: Compositional matrix adjust.
 Identities = 17/44 (38%), Positives = 22/44 (50%), Gaps = 3/44 (6%)
 Frame = +3

Query: 232 GSPPYAAPELF---RDQHYVGVYVDIWALGVLLYFMVTGTMPFR 272
           G  PY APE        H   V  D+W+LG+ L  + TG  P+R
Sbjct: 6   GCRPYMAPERIDPRASSHGYDVRSDVWSLGITLMELATGRFPYR 137
>11404
          Length = 563

 Score = 32.7 bits (73), Expect = 0.31,   Method: Compositional matrix adjust.
 Identities = 40/137 (29%), Positives = 58/137 (42%), Gaps = 7/137 (5%)
 Frame = +1

Query: 74  YRIRGEIGSGNFSQVKLGIHSLTKEKVAIKILDKTKLDQKTQRLLSREISSMEKLHHPN- 132
           Y I   IG G+F QV         E+VAIKI+   K      ++  + +  M +    N 
Sbjct: 145 YEIDSLIGKGSFGQVVKAYDHTDNEQVAIKIIKNKKPFLNQAQIEVKLLEMMNRHDTDNK 324

Query: 133 --IVRLYEVVETLSKLHLVMEYAGGG--ELFGKISTEGKLSEPESKLIFSQILSAVKHMH 188
             IVRL       S L LV E       +L    +  G +S   ++    Q+ +A+  + 
Sbjct: 325 YYIVRLKRHFMFRSHLCLVFELLSYNLYDLLRNTNFRG-VSLNLTRKFAQQLCTALLFLA 501

Query: 189 --ENQIIHRDLKAENVF 203
             E  IIH DLK EN+ 
Sbjct: 502 TPEMSIIHCDLKPENIL 552
>03795
          Length = 1614

 Score = 32.7 bits (73), Expect = 0.33,   Method: Compositional matrix adjust.
 Identities = 20/60 (33%), Positives = 36/60 (60%)
 Frame = +3

Query: 25  VESSCQTEGGKDSEEDQQRQLTPFEKLTQDMCQDEKVVREITLGKRIGFYRIRGEIGSGN 84
           V  S  T+   D EED+Q+ L+ FEK ++ + Q  + + E +L  R   +++ GE+G+G+
Sbjct: 423 VRFSQNTKSXSDDEEDKQQPLSSFEKRSERLRQHIERLEEQSLEPRQ--WQMTGEVGAGD 596
>05627
          Length = 1697

 Score = 32.0 bits (71), Expect = 0.44,   Method: Compositional matrix adjust.
 Identities = 19/57 (33%), Positives = 35/57 (61%)
 Frame = -2

Query: 28  SCQTEGGKDSEEDQQRQLTPFEKLTQDMCQDEKVVREITLGKRIGFYRIRGEIGSGN 84
           S  T+   D EED+Q+ L+ FEK ++ + Q  + + E +L  R   +++ GE+G+G+
Sbjct: 565 SQNTKSTSDDEEDKQQPLSSFEKRSERLRQHIERLEEQSLEPRQ--WQMTGEVGAGD 401
>29360
          Length = 363

 Score = 31.2 bits (69), Expect = 0.92,   Method: Composition-based stats.
 Identities = 34/113 (30%), Positives = 51/113 (45%), Gaps = 6/113 (5%)
 Frame = +3

Query: 96  TKEKVAIKILDKTKLDQKTQRLLSREISSMEKLHHP-----NIVRLYEVVETLSKLHLVM 150
           T E VAIKIL   K      R    E+S +++L        N VR +E  +  +   LV 
Sbjct: 24  TSEIVAIKIL---KNHPSYARQGQIEVSILQRLSQESADDYNFVRAFECFQHKNHTCLVF 194

Query: 151 EYAGGGEL-FGKISTEGKLSEPESKLIFSQILSAVKHMHENQIIHRDLKAENV 202
           E        F K +    L     + I  Q+L+A++ + +  +IH DLK EN+
Sbjct: 195 EMLEQNLYDFLKQNKFQPLPLKYIRPITQQVLTALRKLKQLGLIHADLKPENI 353
>32000
          Length = 644

 Score = 30.8 bits (68), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 19/63 (30%), Positives = 31/63 (49%), Gaps = 6/63 (9%)
 Frame = -1

Query: 210 VKVGDFGFSTV------SKKGEMLNTFCGSPPYAAPELFRDQHYVGVYVDIWALGVLLYF 263
           +K+ DFG + V      +   E++  +     Y APE+     +  V VDIW+LG +   
Sbjct: 572 MKIADFGLARVFGLPVRTYTHEVITLW-----YRAPEILLGCRFYSVPVDIWSLGCIFVE 408

Query: 264 MVT 266
           M+T
Sbjct: 407 MMT 399
>21800
          Length = 855

 Score = 29.3 bits (64), Expect = 3.4,   Method: Compositional matrix adjust.
 Identities = 13/31 (41%), Positives = 19/31 (61%), Gaps = 1/31 (3%)
 Frame = +2

Query: 174 KLIFSQILSAVKHMHEN-QIIHRDLKAENVF 203
           KLI  Q+L  + ++H    IIH D+K EN+ 
Sbjct: 641 KLIIRQVLEGLNYLHAKCNIIHTDIKPENIL 733
>03665
          Length = 598

 Score = 28.1 bits (61), Expect = 6.8,   Method: Compositional matrix adjust.
 Identities = 18/55 (32%), Positives = 32/55 (58%), Gaps = 2/55 (3%)
 Frame = +1

Query: 368 DEHIRNNQGRDARSSITGVYRIILHRVQRRKALES--VPIMILPEPKERDLKKGS 420
           D H++N   + +++++TG  + +L+   RR  + S  VPI +    KER+ K GS
Sbjct: 229 DSHLQN---Q*SQNTLTGAQQSVLYNQARR*LVSSMSVPIYLYLRDKERNGKDGS 384
>18830
          Length = 489

 Score = 28.1 bits (61), Expect = 7.9,   Method: Compositional matrix adjust.
 Identities = 13/32 (40%), Positives = 21/32 (65%), Gaps = 4/32 (12%)
 Frame = -2

Query: 28  SCQTEGGKDS----EEDQQRQLTPFEKLTQDM 55
           +C+ E GK S    E+DQQR+L PF ++  ++
Sbjct: 140 ACEKERGKKSLRK*EDDQQRELFPFSRVESNV 45
>04981
          Length = 1159

 Score = 28.1 bits (61), Expect = 8.0,   Method: Compositional matrix adjust.
 Identities = 12/40 (30%), Positives = 19/40 (47%)
 Frame = -3

Query: 329  PYPTPLEPFQLDPKHLSETSTLKEEENEVKSTLEHLGITD 368
            P P PL+PF L    ++E +  +  +N     L  +G  D
Sbjct: 1088 PQPCPLDPFSLGAAAIAEEAPSEAADNGADFVLPEMGAVD 969
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|170784811|ref|NP_109605.2| regulator of nonsense
transcripts 1 isoform b [Mus musculus]
         (1113 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

04264                                                                 124   3e-28
13484                                                                  89   1e-17
27463                                                                  42   0.002
18666                                                                  40   0.006
19129                                                                  35   0.17 
26408                                                                  32   1.8  
18776                                                                  31   3.3  
07266                                                                  29   9.0  
>04264
          Length = 2736

 Score =  124 bits (310), Expect = 3e-28,   Method: Compositional matrix adjust.
 Identities = 96/297 (32%), Positives = 142/297 (47%), Gaps = 31/297 (10%)
 Frame = -2

Query: 650  KQLILVGDHCQLGPVVMCKKAAKAGLSQSLFERLV---VLGIR-----------PI---R 692
            KQ++L GD  QLGPV+    A K  L  SL ERL+   + G R           P+   +
Sbjct: 2735 KQVVLAGDPQQLGPVLRSPFAKKFKLDVSLMERLMERQMYGRREQAEADNLHYDPLMITK 2556

Query: 693  LQVQYRMHPALSAFPSNIFYEGSLQN-GVTAADRVKKGFDFQWPQPDKPMFFYVTQGQEE 751
            L   YR HPAL   P+ +FY+  L   G         G++   P  + P+ F+   G++ 
Sbjct: 2555 LVRNYRSHPALLEVPNALFYDKDLVTCGPPELTHCMVGWE-ALPNKEMPVIFHAMVGEDM 2379

Query: 752  IASSGTSYLNRTEAANVEKITTKLLKAGA------KPDQIGIITPYEGQRSYLVQYMQFS 805
               +  S+ N  E   V K    L+   +        D IGII+PY  Q    VQ  +  
Sbjct: 2378 QEVNSPSFFNPFEIRQVMKYLDLLVNEKSPRGIKITEDHIGIISPYSKQ----VQ--KIR 2217

Query: 806  GSLHTKLYQEVEIASVDAFQGREKDFIILSCVRAN-------EHQGIGFLNDPRRLNVAL 858
              L  K + ++++ SV+ FQG+E+  II+S VR+N          GIGFL + +R NVA+
Sbjct: 2216 AELRKKSWDKIKVGSVEEFQGQERLIIIVSTVRSNPRFMNTDNKFGIGFLQNNKRFNVAV 2037

Query: 859  TRARYGVIIVGNPKALSKQPLWNHLLSYYKEQKALVEGPLNNLRESLMQFSKPRKLV 915
            TR +  +I++GNP  L     WN  + Y K  K +V+  L+   E    F K R+L+
Sbjct: 2036 TRPKALLIVIGNPNVLRHNKSWNSFVDYSKTNKCMVDAHLDRSDED-DTFRKLRQLM 1869
>13484
          Length = 543

 Score = 88.6 bits (218), Expect = 1e-17,   Method: Compositional matrix adjust.
 Identities = 44/112 (39%), Positives = 66/112 (58%)
 Frame = -1

Query: 775 LLKAGAKPDQIGIITPYEGQRSYLVQYMQFSGSLHTKLYQEVEIASVDAFQGREKDFIIL 834
           L+KAG  P  I +I PY  Q   L Q +       +  Y  +EI SVD FQGREK+ +++
Sbjct: 543 LVKAGISPQDIAVIAPYNLQVELLRQRL-------SAQYPALEIKSVDGFQGREKEAVVI 385

Query: 835 SCVRANEHQGIGFLNDPRRLNVALTRARYGVIIVGNPKALSKQPLWNHLLSY 886
           S VR+N+ + +GFL D RR+NVA+TRAR  + ++ +   ++  P    L+ Y
Sbjct: 384 SFVRSNDRREVGFLADKRRINVAVTRARRHLAVICDSDTVTTDPFLRSLVDY 229
>27463
          Length = 538

 Score = 41.6 bits (96), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 27/71 (38%), Positives = 37/71 (52%), Gaps = 7/71 (9%)
 Frame = +2

Query: 466 LNHSQVYAVKTVLQRPLSLIQGPPGTGKTVTSATIVYHLA--RQGNGP-----VLVCAPS 518
           L+ SQ  A+   L +  S+IQGPPGTGKT     IV  L   R+   P     +L+   +
Sbjct: 320 LDESQYEALNRALTKEFSVIQGPPGTGKTYVGLKIVKALLHNRKTWDPDHSSCMLIVCFT 499

Query: 519 NIAVDQLTEKI 529
           N A+DQ  E +
Sbjct: 500 NHALDQFLEGV 532
>18666
          Length = 463

 Score = 40.0 bits (92), Expect = 0.006,   Method: Composition-based stats.
 Identities = 22/49 (44%), Positives = 33/49 (67%), Gaps = 1/49 (2%)
 Frame = +1

Query: 829 KDFIILSCV-RANEHQGIGFLNDPRRLNVALTRARYGVIIVGNPKALSK 876
           K  II S V  AN  Q   F+++PRR+NV ++RAR  +I++GNP  +S+
Sbjct: 1   KPIIIASLVCAANRTQ---FVSNPRRVNVLISRARTLLILIGNPTTVSE 138
>19129
          Length = 1020

 Score = 35.0 bits (79), Expect = 0.17,   Method: Compositional matrix adjust.
 Identities = 31/135 (22%), Positives = 57/135 (42%), Gaps = 24/135 (17%)
 Frame = +1

Query: 435 YIYHKLLGHEVEDVVIKCQLPKRFTAQGLPDLNHS-------QVYAVKTVLQRPLS---- 483
           Y+ HK+L ++V+ +V           + +PD  +        Q+  +K V++ P+     
Sbjct: 403 YVLHKILPNKVDPLV------SLMMVEKVPDSTYEMVGGLDKQIKEIKEVIELPVKHPEL 564

Query: 484 ------------LIQGPPGTGKTVTSATIVYHLARQGNGPVLVCAPSNIAVDQLTEKIHQ 531
                       L+ GPPGTGKT+ +  + +H           C    ++  +L +K   
Sbjct: 565 FEALGIAQPKGVLLYGPPGTGKTLLARAVAHHTE---------CTFIRVSGSELVQKFIG 717

Query: 532 TGLKVVR-LCAKSRE 545
            G ++VR L   +RE
Sbjct: 718 EGSRMVRELFVMARE 762
>26408
          Length = 463

 Score = 31.6 bits (70), Expect = 1.8,   Method: Composition-based stats.
 Identities = 14/41 (34%), Positives = 24/41 (58%)
 Frame = +1

Query: 463 LPDLNHSQVYAVKTVLQRPLSLIQGPPGTGKTVTSATIVYH 503
           LP + H +++    + Q    L+ GPPGTGKT+ +  + +H
Sbjct: 316 LP-VKHPELFDALGIAQPKGVLLYGPPGTGKTLLARAVAHH 435
>18776
          Length = 841

 Score = 30.8 bits (68), Expect = 3.3,   Method: Composition-based stats.
 Identities = 11/25 (44%), Positives = 19/25 (76%)
 Frame = +2

Query: 846 GFLNDPRRLNVALTRARYGVIIVGN 870
           G   DP ++NVA+TRA+  ++++GN
Sbjct: 2   GVTADPHQMNVAITRAKEVLLVIGN 76
>07266
          Length = 959

 Score = 29.3 bits (64), Expect = 9.0,   Method: Composition-based stats.
 Identities = 13/48 (27%), Positives = 27/48 (56%), Gaps = 4/48 (8%)
 Frame = +2

Query: 466 LNHSQVYAVKTVLQRPLSLIQGPPGTGKTVTSATIVY----HLARQGN 509
           ++H++++    +L    +  QGPPGT  ++T   ++     H+AR+ N
Sbjct: 308 ISHTKIHQTHIILYTMTARRQGPPGTNPSLTPVCLLCLQSPHIAREAN 451
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|71534295|ref|NP_001025154.1| mannosidase, alpha,
class 1B, member 1 [Mus musculus]
         (658 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

19118                                                                 122   3e-28
18075                                                                  83   3e-16
27298                                                                  57   2e-08
32083                                                                  47   2e-05
12632                                                                  30   3.0  
>19118
          Length = 441

 Score =  122 bits (307), Expect = 3e-28,   Method: Compositional matrix adjust.
 Identities = 59/143 (41%), Positives = 96/143 (67%), Gaps = 2/143 (1%)
 Frame = +2

Query: 250 LIDALDTMWILGLKQEFKQARKWVSENLDFQKNVDVNLFESTIRILGGLLSTYHLSGDSL 309
           ++DA+DT++I+GL++E+K+AR W++ +L F+ + ++++FE+ IR +GGLL+ Y L+GD +
Sbjct: 2   IVDAVDTLYIMGLEEEYKKARDWIATSLTFEGSSELSVFETNIRFIGGLLAAYALTGDQM 181

Query: 310 FLTKAEDFGKRLMPAFTTPSKIPYSDVNIGTGFAHSPQWTSD--STVAEVTSIQLEFREL 367
           F  K++    +LMPAF TP+ IPYS VNI TG A +  W S   S ++E  S+ LEF  L
Sbjct: 182 FKKKSQVIADKLMPAFNTPTGIPYSMVNIKTGTARNWGWASGGCSILSEFGSLHLEFYYL 361

Query: 368 SRLTGIKKFQEAVEEVTKHIHSL 390
           S +T   K+ +   +V   +  L
Sbjct: 362 SAITQDGKYLDKANKVRTVLQQL 430
>18075
          Length = 424

 Score = 83.2 bits (204), Expect = 3e-16,   Method: Composition-based stats.
 Identities = 47/146 (32%), Positives = 76/146 (52%), Gaps = 1/146 (0%)
 Frame = +2

Query: 422 DSYYEYLLKQWIQGGKKETQLLEDYVKAIEGIKAHLLRQSQPRKLTFVGELAHGRFSAKM 481
           DS+YEYLLK ++  G+++    E Y K I+ +   ++ Q+    L +  E   GR   KM
Sbjct: 2   DSFYEYLLKSYLLSGQEDMVAKEMYDKTIQAMIDKMV-QTSKSGLKYFAEYKSGRIEHKM 178

Query: 482 DHLVCFLPGTLALGVHHGLPAD-HMDLARALMETCYQMNQQMETGLSPEIAHFNMYPRAD 540
           DHL CF  G LALG  H    + ++ L   L  TC++   +    L PE   F+     +
Sbjct: 179 DHLSCFSGGMLALGAKHSEDKEKYLKLGADLAHTCHESYDRTAVKLGPEAFRFD----GN 346

Query: 541 HKDVEVKPADRHNLLRPETVESLFYL 566
            + +  +  +++ +LRPE VE+ FY+
Sbjct: 347 SEAIATRSNEKYYILRPEVVETYFYM 424
>27298
          Length = 377

 Score = 57.4 bits (137), Expect = 2e-08,   Method: Composition-based stats.
 Identities = 39/125 (31%), Positives = 62/125 (49%), Gaps = 1/125 (0%)
 Frame = +2

Query: 307 DSLFLTKAEDFGKRLMPAF-TTPSKIPYSDVNIGTGFAHSPQWTSDSTVAEVTSIQLEFR 365
           D   L+ A D   RL+PAF  T + IPY  V++  G        +++ +A   ++ LEF 
Sbjct: 11  DGELLSLAHDLAARLLPAFDNTATGIPYPRVSLSEGV--RADCVNETCIAGAGTLLLEFG 184

Query: 366 ELSRLTGIKKFQEAVEEVTKHIHSLSGKKDGLVPMFINTNSGLFTHPGVFTLGARADSYY 425
            LSRL     ++   E+  + +        GL+   IN  +G + +  +  LGA  DS+Y
Sbjct: 185 VLSRLLSDPVYEFYAEQAVRMLWKYRSNVTGLLGNVINIQTGEWVNK-MSGLGAGMDSFY 361

Query: 426 EYLLK 430
           EYL+K
Sbjct: 362 EYLIK 376
>32083
          Length = 421

 Score = 47.4 bits (111), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 28/72 (38%), Positives = 41/72 (56%)
 Frame = -2

Query: 548 PADRHNLLRPETVESLFYLYRVTRDRKYQDWGWEILQSFNKYTRVPSGGYSSINNVQNSH 607
           P  R   LRPE VES ++LY+ TR+  Y   G +IL S + + +    GY ++++V    
Sbjct: 414 PDVRFYPLRPELVESTYFLYQATRNPFYLHVGKDILTSLSTHAKAKC-GYGTLHDVNTK- 241

Query: 608 KPEPRDKMESFF 619
             E  D+MESFF
Sbjct: 240 --ELEDRMESFF 211
>12632
          Length = 481

 Score = 30.0 bits (66), Expect = 3.0,   Method: Compositional matrix adjust.
 Identities = 16/46 (34%), Positives = 22/46 (47%)
 Frame = -2

Query: 406 SGLFTHPGVFTLGARADSYYEYLLKQWIQGGKKETQLLEDYVKAIE 451
            G   + G   L  R   +Y  L+ Q +QGG +   LL DY+ A E
Sbjct: 417 GGHLGYRGPVHLRERHGMFYRRLMSQRVQGGPQVNVLLADYLPAPE 280
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|20373167|ref|NP_619621.1| LUC7-like 2 [Mus musculus]
         (392 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

20660                                                                 121   4e-28
08435                                                                  42   3e-04
21003                                                                  28   9.1  
>20660
          Length = 534

 Score =  121 bits (304), Expect = 4e-28,   Method: Compositional matrix adjust.
 Identities = 59/102 (57%), Positives = 70/102 (68%)
 Frame = -3

Query: 135 KLLAKVEQLGAEGNVEESQKVMDXXXXXXXXXXXXXXXYRNSMPASSFQQQKLRVCEVCS 194
           K   K E LG  G VE+S ++M                YR SMPAS++QQQKLRVCEVCS
Sbjct: 484 KNWPKAEALGEAGEVEDSMELMKEIDELRGKKIKAEHEYRTSMPASTYQQQKLRVCEVCS 305

Query: 195 AYLGLHDNDRRLADHFGGKLHLGFIEIREKLEELKRVVAEKQ 236
           AYLG+HDND RLADHFGGKLHLGF+ IREKL EL++  A ++
Sbjct: 304 AYLGIHDNDIRLADHFGGKLHLGFLTIREKLIELEKTAAPRK 179
>08435
          Length = 1958

 Score = 42.4 bits (98), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 17/44 (38%), Positives = 29/44 (65%)
 Frame = -3

Query: 183  QQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFIEIREKLE 226
            Q +++ VCEVC A+L + D  +R  +H  GK H G+  +R+++E
Sbjct: 1887 QFKQMEVCEVCGAFLIVDDAPQRQDEHLMGKQHAGYARVRDEIE 1756
>21003
          Length = 379

 Score = 27.7 bits (60), Expect = 9.1,   Method: Compositional matrix adjust.
 Identities = 15/46 (32%), Positives = 23/46 (50%)
 Frame = -2

Query: 4   QAQMRAMLDQLMGTSRDGDTTRQRIKFSDDRVCKSHLLNCCPHDVL 49
           Q ++ A+L Q  G+ R  ++  + +    DR   S  L CCP D L
Sbjct: 363 QGEVTALLQQSHGSRRSAESMARHLLHRLDRNHGSQALTCCPWDDL 226
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|68299757|ref|NP_081724.1| Leber congenital amaurosis
5 isoform b [Mus musculus]
         (704 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

10536                                                                 122   4e-28
30643                                                                  31   1.8  
18206                                                                  30   2.8  
>10536
          Length = 1110

 Score =  122 bits (307), Expect = 4e-28,   Method: Compositional matrix adjust.
 Identities = 76/205 (37%), Positives = 124/205 (60%)
 Frame = -3

Query: 101  DIVTKRVLSARLLKINELQNEVSELQVKLAQLLKENKALKSLQYRQEKALNKFEDAENEI 160
            D VTKR+LSA  L + ELQNE+ +++ +L  +  ENK  K LQ +QE+AL KFED E+++
Sbjct: 1051 DEVTKRLLSANYLHMKELQNEMEDVKKQLEAVSDENKVFKRLQRKQERALTKFEDTESQL 872

Query: 161  SQLIHRHNNEITALKERLRKSQEKERATEKRVKETEGELFRTKFSLQKLKKISEARHLPE 220
             Q++ +HNNE+ ALKE+LR ++EK   T++ + + E EL +    ++K + ++E ++L E
Sbjct: 871  PQMLRKHNNEVRALKEQLRHAREKFDRTDRYLHDAEDELEKATSQMKKYRALTEKKNLGE 692

Query: 221  RDDLAKKLVSAELKLDDTERKIKELSKNLELSTNSFQRQLLAERKRAFEAYDENKVXXXX 280
            R DL ++L + EL L++   +I EL +++EL   + + +L  ER R  EA  +       
Sbjct: 691  RSDLDRRLNNVELTLEEKSSRIAELERHVELVKKNHRHELGIERARCKEALKQIDEIKEE 512

Query: 281  XXXXXXXXXXXXXXXDIKNIYANRL 305
                           + KNIY+NR+
Sbjct: 511  KXKLELQVREKEKLLEAKNIYSNRM 437
>30643
          Length = 554

 Score = 30.8 bits (68), Expect = 1.8,   Method: Compositional matrix adjust.
 Identities = 33/115 (28%), Positives = 60/115 (52%)
 Frame = -2

Query: 64  HHPTVRKVSPKAVPSKKGIRVGFRSQSLNREPLRKDPDIVTKRVLSARLLKINELQNEVS 123
           H    R V+  AV SKK + V    Q LN E  +++ +++ +         +  +QN+VS
Sbjct: 388 HSAPSRIVNRIAVCSKKRLDVAL--QGLN-EAKKQNHNLMER---------LQTMQNDVS 245

Query: 124 ELQVKLAQLLKENKALKSLQYRQEKALNKFEDAENEISQLIHRHNNEITALKERL 178
           E +V+ A+L  + + L +L       L + ++AE E++Q + +  +E  AL ER+
Sbjct: 244 ESEVRCAELEGQIRQLNNL-------LVQRQEAEQELNQRMQKSQSEKQALVERV 101
>18206
          Length = 425

 Score = 30.4 bits (67), Expect = 2.8,   Method: Composition-based stats.
 Identities = 14/51 (27%), Positives = 30/51 (58%)
 Frame = +2

Query: 146 QEKALNKFEDAENEISQLIHRHNNEITALKERLRKSQEKERATEKRVKETE 196
           ++ AL+  +   + I+ ++HR N +ITA++  ++   + +  T + VKE E
Sbjct: 5   EKHALSLLQQHIHTITAIVHRLNADITAIESSIKSRDQAQVGTNRAVKELE 157
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6680710|ref|NP_031498.1| aquaporin 1 [Mus musculus]
         (269 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

17581                                                                 120   5e-28
20627                                                                  58   5e-09
11675                                                                  39   0.002
08920                                                                  30   0.79 
05800                                                                  28   5.3  
>17581
          Length = 466

 Score =  120 bits (301), Expect = 5e-28,   Method: Compositional matrix adjust.
 Identities = 61/140 (43%), Positives = 88/140 (62%), Gaps = 2/140 (1%)
 Frame = +2

Query: 95  VMYIIAQCVGAIVATAILSGITSSLVDNSLGRNDL--AHGVNSGQGLGIEIIGTLQLVLC 152
           ++YI++Q +G I+  AIL G+T      +LG   +  A GV + QG G+E++ T   V+ 
Sbjct: 2   ILYILSQIIGGILGAAILYGLTPEGRRGTLGATVISDAGGVTAAQGFGVEMLITFIFVMA 181

Query: 153 VLATTDRRRRDLGGSAPLAIGLSVALGHLLAIDYTGCGINPARSFGSAVLTRNFSNHWIF 212
             A+ D  R DL GS PL +GL+V +  L AIDYT  G+N ARSFG AV+   + +HW++
Sbjct: 182 FFASRDSNRSDLAGSYPLTVGLAVVVCQLFAIDYTAAGMNCARSFGPAVIMGIWDDHWVY 361

Query: 213 WVGPFIGGALAVLIYDFILA 232
           WVGP  GG  A L+YD+I +
Sbjct: 362 WVGPLSGGITAGLLYDYIFS 421
>20627
          Length = 566

 Score = 57.8 bits (138), Expect = 5e-09,   Method: Compositional matrix adjust.
 Identities = 33/76 (43%), Positives = 47/76 (61%), Gaps = 5/76 (6%)
 Frame = -2

Query: 168 APLAIGLSVALGHLLAIDYTGCGINPARSFGSAV-----LTRNFSNHWIFWVGPFIGGAL 222
           APLAIGL+VA   L  +  TG  +NPARSFG AV      +  ++ H+++WVGP +G  +
Sbjct: 454 APLAIGLAVAADILAGVTITGASMNPARSFGPAVTISFATSDYWTYHYVYWVGPLVGSIV 275

Query: 223 AVLIYDFILAPRSSDF 238
           A + Y   LA  SS++
Sbjct: 274 AGIWYRVFLA--SSEY 233
>11675
          Length = 675

 Score = 39.3 bits (90), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 29/104 (27%), Positives = 46/104 (44%), Gaps = 14/104 (13%)
 Frame = +3

Query: 142 EIIGTLQLVLCVLATTD-RRRRDLGGSAPLAIG-LSVALGHLLAIDYTGCGINPARSFGS 199
           ++  T  L+ C+LA  D    +   G AP+A+G +  A+G     +  G  +NPAR    
Sbjct: 294 QVFATFILISCILAIIDGHNMKPDKGLAPIALGSIVFAIGTCWGFN-CGYPLNPARDLAP 470

Query: 200 AVLT------------RNFSNHWIFWVGPFIGGALAVLIYDFIL 231
              T            RN++  W+   GP  G  LA L+Y+  +
Sbjct: 471 RAFTALAXWGVEPFSYRNYNWFWVPIAGPMXGSVLAWLLYNLFI 602

 Score = 38.5 bits (88), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 19/39 (48%), Positives = 26/39 (66%)
 Frame = +2

Query: 68  GHISGAHLNPAVTLGLLLSCQISILRAVMYIIAQCVGAI 106
           G ++GA +NPAVT GL L   ++  + V Y+IAQ VGA 
Sbjct: 26  GGVTGACVNPAVTFGLCLQGIVAWRKYVFYVIAQFVGAF 142
>08920
          Length = 996

 Score = 30.4 bits (67), Expect = 0.79,   Method: Compositional matrix adjust.
 Identities = 20/53 (37%), Positives = 29/53 (54%), Gaps = 3/53 (5%)
 Frame = +1

Query: 174 LSVALGHLLAIDYTGCGINPARSFGSAVL--TRNFSNHW-IFWVGPFIGGALA 223
           L+ AL  +  +  TG   NPA + G  +   T  F  H+ ++W+GPFIG  LA
Sbjct: 94  LNAALMIVFGLQTTGMYFNPAMASGHTLGCGTTLFWEHFAVYWLGPFIGCFLA 252
>05800
          Length = 1146

 Score = 27.7 bits (60), Expect = 5.3,   Method: Compositional matrix adjust.
 Identities = 14/34 (41%), Positives = 20/34 (58%), Gaps = 2/34 (5%)
 Frame = -2

Query: 118  SLVDNSLGRNDLAHGVNSGQGLG--IEIIGTLQL 149
            +L     GRN   HGV++G GLG  +   GTL++
Sbjct: 1049 TLATEETGRNVRGHGVHAGSGLGWLVWRAGTLKM 948
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|58037481|ref|NP_084101.1| Sec1 family domain
containing 1 [Mus musculus]
         (639 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

36169                                                                 103   7e-28
19817                                                                  34   0.19 
>36169
          Length = 1108

 Score =  103 bits (257), Expect(2) = 7e-28,   Method: Compositional matrix adjust.
 Identities = 45/60 (75%), Positives = 53/60 (88%)
 Frame = -1

Query: 552  MEMKSNPETDDYRYFDPKMLRSNDSSVPRNKSPFQEAIVFVVGGGNYIEYQNLVDYIKAK 611
            ME+KS  E DD+RYFDPKMLR++  +VPRNKSPFQEA VFVVGGGNYIEYQNL+DY ++K
Sbjct: 1108 MELKSLQEVDDFRYFDPKMLRADSGNVPRNKSPFQEAFVFVVGGGNYIEYQNLIDYARSK 929

 Score = 38.9 bits (89), Expect(2) = 7e-28,   Method: Compositional matrix adjust.
 Identities = 14/24 (58%), Positives = 22/24 (91%)
 Frame = -3

Query: 614 KHILYGCSEIFNATQFIKQLSQLG 637
           + I+YGCS++ NA+QF++QL+QLG
Sbjct: 914 EKIVYGCSDLVNASQFLRQLAQLG 843
>19817
          Length = 1203

 Score = 33.9 bits (76), Expect = 0.19,   Method: Compositional matrix adjust.
 Identities = 25/86 (29%), Positives = 43/86 (50%), Gaps = 2/86 (2%)
 Frame = -2

Query: 290  NLEESTGVENSPAGARPKRKNKKSYDLTPVDKFWQKHKGSPFPE--VAESVQQELESYRA 347
            N++E    EN   G RP  +N  +   TP D+     KGSP P+   + +  ++  S+  
Sbjct: 1046 NIDEKKNAENR-FGRRPSDRNTPTGRKTPTDRNTPTDKGSPGPKRRFSPTDARDKHSFSG 870

Query: 348  QEDEVKRLKSIMGLEGEDEGAISMLS 373
            ++   + L+     E +DEG+ S+LS
Sbjct: 869  RKSPAEGLRKEDKTEKKDEGSSSLLS 792
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|7242199|ref|NP_033053.2| RAS protein-specific guanine
nucleotide-releasing factor 2 [Mus musculus]
         (1189 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

12552                                                                 122   8e-28
32091                                                                  52   2e-06
13952                                                                  40   0.004
26155                                                                  39   0.009
27925                                                                  33   0.59 
02184                                                                  31   3.4  
>12552
          Length = 1266

 Score =  122 bits (306), Expect = 8e-28,   Method: Compositional matrix adjust.
 Identities = 70/239 (29%), Positives = 131/239 (54%), Gaps = 7/239 (2%)
 Frame = -3

Query: 953  LSAMELAEQITLLDHIVFRSIPYEEFLGQGWMKLDKNERTPYIMKTSQHFNEMSNLVASQ 1012
            +S  E A QI L+D  VF+SI  +E     W   +K  + P ++  ++ FN ++  V  +
Sbjct: 970  VSPEEFASQIXLMDLPVFKSIQPDELTSCAWTTKEKLIKAPNVVAFTRRFNHVNFWVQRE 791

Query: 1013 IMNYADISSRANAIEKWVAVADICRCLHNYNGVLEITSALNRSAIYRLKKTWAKVSKQTK 1072
            I+N   + +RA+ +  ++ +A     L+N + V+ + SAL  +AI+RL  TW  +SK+ K
Sbjct: 790  ILNCQTLKTRADVLAHFIKIAKKLLELNNLHAVMAVISALQSAAIFRLSGTWMMLSKKDK 611

Query: 1073 ALMDKLQKTVSSEGRFKNLRETLKNCNPPAVPYLGMYLTDLAFIEEGTPNFTEEGLVNFS 1132
             + +++    S     + LR+ + N   P +PYLG+YLTDL +I+   P+    G+ +  
Sbjct: 610  LMYERMADMFSECNNRQKLRDVMDNVKLPCIPYLGLYLTDLIYIDVAHPH--SGGMESQP 437

Query: 1133 KMRMISHIIREIRQFQQTAY-------RIDQQPKVIQYLLDKALVIDEDSLYELSLKIE 1184
            +   +++I+R I  FQQ+ Y        +    + ++Y+ +    +++D+ Y+LSLK+E
Sbjct: 436  RQTQMNNILRVIADFQQSTYDHLPLLDHVQNYLRSVRYIEELQKFVEDDN-YKLSLKLE 263
>32091
          Length = 348

 Score = 51.6 bits (122), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 28/93 (30%), Positives = 48/93 (51%)
 Frame = +3

Query: 952  TLSAMELAEQITLLDHIVFRSIPYEEFLGQGWMKLDKNERTPYIMKTSQHFNEMSNLVAS 1011
            +   +++AEQ+TLLD  +F+ I   E L   W K    E +P +   ++HFN+MS    +
Sbjct: 72   SFKTLDIAEQMTLLDAQLFQKIEIPEVLL--WAKEQSEELSPNLTTFTEHFNKMSYWCRT 245

Query: 1012 QIMNYADISSRANAIEKWVAVADICRCLHNYNG 1044
            +I+   D   R   + K++ +    R L N+N 
Sbjct: 246  RILTQEDPKEREKYLMKFIKIMRCLRKLKNFNS 344
>13952
          Length = 577

 Score = 40.4 bits (93), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 20/62 (32%), Positives = 28/62 (45%), Gaps = 1/62 (1%)
 Frame = -3

Query: 24  TKRGFLSKKAAEASRWHEKWFALYQNVLFYFEGEQSGRPAGMYLLEGCSC-ERTPAPPRT 82
            K G+L K+      W  +WF L  N L+YF+      P G+  LE     E +    R+
Sbjct: 419 VKEGWLMKQGGRYKNWKRRWFILNDNCLYYFQYTADKEPKGIIPLENIQVRELSEKSSRS 240

Query: 83  NA 84
           NA
Sbjct: 239 NA 234
>26155
          Length = 693

 Score = 39.3 bits (90), Expect = 0.009,   Method: Compositional matrix adjust.
 Identities = 15/62 (24%), Positives = 34/62 (54%)
 Frame = -1

Query: 1103 VPYLGMYLTDLAFIEEGTPNFTEEGLVNFSKMRMISHIIREIRQFQQTAYRIDQQPKVIQ 1162
            +P+  +++ DL F+ EG  N   +G +NF K  +++  + ++  +QQ      +  +V+ 
Sbjct: 630  IPFFSLFVKDLYFLNEGCSNRHCDGNINFEKCWVLAKHVSDLIAWQQVECPYPKNSRVMH 451

Query: 1163 YL 1164
            Y+
Sbjct: 450  YV 445
>27925
          Length = 370

 Score = 33.5 bits (75), Expect = 0.59,   Method: Composition-based stats.
 Identities = 14/48 (29%), Positives = 24/48 (50%), Gaps = 1/48 (2%)
 Frame = +3

Query: 31 KKAAEASRWHEKWFALY-QNVLFYFEGEQSGRPAGMYLLEGCSCERTP 77
          K A    +W  +WF+L   N L+Y++ E   +P G  ++   + E  P
Sbjct: 3  KGAPNTKKWVRRWFSLRPDNCLYYYKTEDDSQPVGAMIMAKHTVELCP 146
>02184
          Length = 942

 Score = 30.8 bits (68), Expect = 3.4,   Method: Composition-based stats.
 Identities = 19/62 (30%), Positives = 27/62 (43%), Gaps = 2/62 (3%)
 Frame = +1

Query: 3   KSVRYNEGHALYLAMLARKEGTKRGFLSKKAAEASRWHEKWFALYQNVLFYFEGEQSG-- 60
           K  ++  G    +    RK  T  GF+  K A+  RW +KW    + +  Y   EQ G  
Sbjct: 349 KCPKFRLGRPYLIVARQRKRDTSLGFVVDKTAKVIRWKDKW---NRRLKHYLRREQRGLC 519

Query: 61  RP 62
           RP
Sbjct: 520 RP 525
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|27229036|ref|NP_080406.1| signal recognition particle
receptor [Mus musculus]
         (636 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

20049                                                                 121   1e-27
13004                                                                  33   0.31 
>20049
          Length = 578

 Score =  121 bits (303), Expect = 1e-27,   Method: Compositional matrix adjust.
 Identities = 60/114 (52%), Positives = 83/114 (72%), Gaps = 2/114 (1%)
 Frame = -2

Query: 45  NSFTHEALTLKYKLDNQFELVFVVGFQKILTLTYVDKLIDDVHRLFRDKYRTEIQQQSAL 104
           ++FTHE+LTLKYKLDN+FELVFVVG+QKIL L+Y+DK + D+   FR+KY+ E+   +  
Sbjct: 574 DTFTHESLTLKYKLDNEFELVFVVGYQKILQLSYIDKFLSDIQLEFRNKYKDELLHGN-- 401

Query: 105 SLLNGTFDFQNDFLRLLREAEESSK--IRAPTTMKKFEDSEKAKKPVRSMIETR 156
             + G FDF + F  +LR  E+ SK   +AP  M+ FEDS+K+KK V SMIE++
Sbjct: 400 --VTGNFDFSSSFQAMLRLREDESKQEAKAPKKMRGFEDSQKSKKTVASMIESK 245
>13004
          Length = 884

 Score = 33.1 bits (74), Expect = 0.31,   Method: Compositional matrix adjust.
 Identities = 22/69 (31%), Positives = 33/69 (47%), Gaps = 5/69 (7%)
 Frame = -1

Query: 548 VGEALVGNE--AVDQLVKFNRALADHS---MAQTPRLIDGIVLTKFDTIDDKVGAAISMT 602
           +GE + GNE  +V +  K +     HS   +       D + LTK  TIDD +    S T
Sbjct: 326 LGEMVTGNE*SSVPKYHKLHETTQGHS*HALCFATGNEDSLRLTKQRTIDDTIHTHKSTT 147

Query: 603 YITSKPIVF 611
           + + +P VF
Sbjct: 146 HFSHRPFVF 120
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31560391|ref|NP_062719.2| programmed cell death 10
[Mus musculus]
         (212 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

31024                                                                  74   1e-27
>31024
          Length = 751

 Score = 73.9 bits (180), Expect(2) = 1e-27,   Method: Compositional matrix adjust.
 Identities = 38/75 (50%), Positives = 52/75 (69%), Gaps = 1/75 (1%)
 Frame = -1

Query: 76  FTESLLRMAAD-DVEEYMIERPEPEFQDLNEKARALKQILSKIPDEINDRVRFLQTIKDI 134
             ++LLR+    + E+  I R EP F++LN  A  LK+IL +IPD+I DR +FL+TIK+I
Sbjct: 691 LCQTLLRLGGQTETEDIRIPRSEPTFRELNTCAIDLKRILGRIPDQIADRKQFLETIKEI 512

Query: 135 ASAIKELLDTVNNVF 149
           AS+IK LLD VN V 
Sbjct: 511 ASSIKTLLDAVNRVI 467

 Score = 65.9 bits (159), Expect(2) = 1e-27,   Method: Compositional matrix adjust.
 Identities = 34/55 (61%), Positives = 44/55 (80%), Gaps = 2/55 (3%)
 Frame = -3

Query: 157 RRALEHQKKEFVKYSKSFSDTLKTYFKDGKAIN--VFISANRLIHQTNLILQTFK 209
           ++ LE +KKEFV+YSK FS+TLK YF+D   +N  VF+SAN L+HQTNLIL+T K
Sbjct: 431 KQVLEDRKKEFVRYSKKFSNTLKEYFRD-PTLNQSVFLSANHLVHQTNLILKTVK 270
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|54292132|ref|NP_803155.1| phosphoserine
aminotransferase 1 [Mus musculus]
         (370 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

33166                                                                 119   1e-27
06641                                                                  32   0.40 
>33166
          Length = 290

 Score =  119 bits (299), Expect = 1e-27,   Method: Compositional matrix adjust.
 Identities = 56/94 (59%), Positives = 70/94 (74%)
 Frame = +3

Query: 271 SSIKSQMIYEIIDNSQGFYVCPVERQNRSRMNIPFRIGNAKGDEALEKRFLDKAVELNMI 330
           S  KS++IY+II  S+GFY CPV    RS MN+PFRIG+  G+E LEK FL KA  + MI
Sbjct: 6   SEAKSKLIYDIIGKSEGFYYCPVMPHVRSHMNVPFRIGSKTGNEQLEKEFLTKAEAVGMI 185

Query: 331 SLKGHRSVGGIRASLYNAVTTEDVEKLAAFMKNF 364
            LKGHRSVGGIRASLYNA+T ++ ++LA  M +F
Sbjct: 186 QLKGHRSVGGIRASLYNAITLDETQQLAKLMLSF 287
>06641
          Length = 726

 Score = 32.0 bits (71), Expect = 0.40,   Method: Compositional matrix adjust.
 Identities = 11/38 (28%), Positives = 19/38 (50%)
 Frame = -2

Query: 138 STWNLNPDASYVYFCANETVHGVEFDFVPDVKGAVLVC 175
           ++W+    AS ++FC +  +  V F F  DV   +  C
Sbjct: 233 ASWSNMSKASVIFFCVSAIIESVLFSFASDVSAMLFTC 120
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6679591|ref|NP_033026.1| RAB24, member RAS oncogene
family [Mus musculus]
         (203 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

09204                                                                 119   1e-27
33374                                                                  99   2e-26
08428                                                                 108   1e-24
26083                                                                  98   2e-21
17511                                                                  89   9e-19
13901                                                                  84   3e-17
34468                                                                  80   6e-16
05468                                                                  79   1e-15
07465                                                                  77   5e-15
14456                                                                  76   1e-14
35581                                                                  67   4e-12
11728                                                                  66   8e-12
27191                                                                  54   2e-10
19656                                                                  61   3e-10
33380                                                                  60   8e-10
01398                                                                  59   2e-09
29380                                                                  55   1e-08
13750                                                                  55   2e-08
19006                                                                  55   2e-08
26536                                                                  55   2e-08
01095                                                                  54   4e-08
01972                                                                  52   1e-07
33794                                                                  52   2e-07
32723                                                                  49   1e-06
34359                                                                  48   3e-06
11257                                                                  47   6e-06
30760                                                                  46   1e-05
31291                                                                  45   2e-05
00552                                                                  41   4e-04
14119                                                                  40   6e-04
14775                                                                  39   0.002
12339                                                                  36   0.012
33605                                                                  35   0.019
10708                                                                  35   0.022
13745                                                                  34   0.037
10862                                                                  30   0.078
00858                                                                  33   0.10 
12443                                                                  32   0.23 
>09204
          Length = 1051

 Score =  119 bits (297), Expect = 1e-27,   Method: Compositional matrix adjust.
 Identities = 56/105 (53%), Positives = 75/105 (71%)
 Frame = -3

Query: 69   RYEAMSRIYYRGAKAAIVCYDLTDSSSFERAKFWVKELRSLEEGCQIYLCGTKSXXXXXX 128
            RYEAMSRIYYRGAKAAI+C+DLTD SSF+R +FW+ ELR  EE C++Y+CGTK       
Sbjct: 1049 RYEAMSRIYYRGAKAAILCFDLTDKSSFDRIRFWIGELRQHEEECKLYICGTKFDLVHDD 870

Query: 129  XXXXXVDFHDVQDYADNIKAQLFETSSKTGQSVDELFQKVAEDYV 173
                 V     +  AD+  A+++ETSS TG ++++LF K+AEDY+
Sbjct: 869  PERRAVPRSVAKALADDCMAEIYETSSMTGDNIEKLFTKIAEDYM 735
>33374
          Length = 489

 Score = 99.4 bits (246), Expect(2) = 2e-26,   Method: Compositional matrix adjust.
 Identities = 51/121 (42%), Positives = 72/121 (59%), Gaps = 1/121 (0%)
 Frame = +1

Query: 45  FVAKVMCVGDRTVTLGIWDTAGSERYEAMSRIYYRGAKAAIVCYDLTDSSSFERAKFWVK 104
           F+ + +C+ D TV   IWDTAG ERY +++ +YYRGA+AAIV YD+T+  +F RAK WVK
Sbjct: 139 FLTQTVCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNQDTFGRAKTWVK 318

Query: 105 EL-RSLEEGCQIYLCGTKSXXXXXXXXXXXVDFHDVQDYADNIKAQLFETSSKTGQSVDE 163
           EL R       I L G K+           V+F + Q YA+       ETS+KT  +V++
Sbjct: 319 ELQRQASPNIVIALAGNKA----DLANKRMVEFEEAQAYAEENSLLFMETSAKTAMNVND 486

Query: 164 L 164
           +
Sbjct: 487 I 489

 Score = 36.2 bits (82), Expect(2) = 2e-26,   Method: Compositional matrix adjust.
 Identities = 22/44 (50%), Positives = 30/44 (68%), Gaps = 1/44 (2%)
 Frame = +2

Query: 3  GQRVDVKVVMLGKEYVGKTSLVERYVHDRFLVGPYQ-NTIGAAF 45
          G+    K+V+LG+  VGK+SLV R+V  +F    YQ +TIGAAF
Sbjct: 17 GKICQFKLVLLGESAVGKSSLVLRFVKGQF--HEYQESTIGAAF 142
>08428
          Length = 1109

 Score =  108 bits (271), Expect = 1e-24,   Method: Compositional matrix adjust.
 Identities = 66/171 (38%), Positives = 98/171 (57%), Gaps = 2/171 (1%)
 Frame = -3

Query: 1    MSGQRVDVKVVMLGKEYVGKTSLVERYVHDRFLVGPYQ-NTIGAAFVAKVMCVGDRTVTL 59
            M  Q  DVKV +LG   VGK+S+V R+V   +   P Q +TIGA+F++K + V       
Sbjct: 1089 MRMQMRDVKVCLLGDSGVGKSSIVLRFVTGSYR--PSQESTIGASFMSKSLVVDGAGYRF 916

Query: 60   GIWDTAGSERYEAMSRIYYRGAKAAIVCYDLTDSSSFERAKFWVKELRSL-EEGCQIYLC 118
             IWDTAG E++ A++ +YYRGA AA++ YD+T   +F+  K W++ELRS       + + 
Sbjct: 915  QIWDTAGQEKFRALAPMYYRGAAAAVIVYDVTRPRTFKSVKSWIQELRSFGPPNIVLAIA 736

Query: 119  GTKSXXXXXXXXXXXVDFHDVQDYADNIKAQLFETSSKTGQSVDELFQKVA 169
            G K            V   D Q+YA +I A   ETS+ T  +V+E+F ++A
Sbjct: 735  GNKC----DLEELREVVEKDAQEYASSISAIFGETSAMTAVNVEEMFTELA 595
>26083
          Length = 432

 Score = 97.8 bits (242), Expect = 2e-21,   Method: Compositional matrix adjust.
 Identities = 49/115 (42%), Positives = 75/115 (65%), Gaps = 2/115 (1%)
 Frame = +1

Query: 9   KVVMLGKEYVGKTSLVERYVHDRFLVGPYQNTIGAAFVAKVMCVGDRTVTLGIWDTAGSE 68
           K+V LG++ VGKTSL+ R+++D F    YQ TIG  F++K M + DRT+ L +WDTAG E
Sbjct: 82  KLVFLGEQSVGKTSLITRFMYDSF-DNTYQATIGIDFLSKTMYLEDRTIRLQLWDTAGQE 258

Query: 69  RYEAMSRIYYRGAKAAIVCYDLTDSSSFERAKFWVKELRSLEEGCQ--IYLCGTK 121
           R+ ++   Y R +  A+V YD+T+++SF +   W+ ++R+ E G    I L G K
Sbjct: 259 RFRSLIPSYIRDSSVAVVVYDITNANSFHQTSKWIDDVRT-ERGSDVIIMLVGNK 420
>17511
          Length = 483

 Score = 89.4 bits (220), Expect = 9e-19,   Method: Compositional matrix adjust.
 Identities = 44/105 (41%), Positives = 68/105 (64%)
 Frame = -3

Query: 2   SGQRVDVKVVMLGKEYVGKTSLVERYVHDRFLVGPYQNTIGAAFVAKVMCVGDRTVTLGI 61
           S ++V +KV++LG   VGKTSL+ +YV+ +F    Y+ TIGA F+ K + V DR VT+ I
Sbjct: 382 SRKKVLLKVIILGDSGVGKTSLMNQYVNKKF-SNQYKATIGADFLTKEVMVDDRLVTMQI 206

Query: 62  WDTAGSERYEAMSRIYYRGAKAAIVCYDLTDSSSFERAKFWVKEL 106
           WDTAG ER++++   +YRGA   ++ +D+T  ++F     W  E 
Sbjct: 205 WDTAGQERFQSLGVAFYRGADCCVLVFDVTMPNTFRSLDSWRDEF 71
>13901
          Length = 962

 Score = 84.3 bits (207), Expect = 3e-17,   Method: Compositional matrix adjust.
 Identities = 43/103 (41%), Positives = 65/103 (63%), Gaps = 1/103 (0%)
 Frame = -3

Query: 1   MSGQRVDVKVVMLGKEYVGKTSLVERYVHDRFLVGPYQNTIGAAFVAKVMCVGDR-TVTL 59
           +  + V  KV+++G   VGKTS V+RYV+D F    Y+ TIG  F  KV+   D+  + L
Sbjct: 306 IMSEEVLFKVIIIGDPTVGKTSFVQRYVNDSFR-RDYKMTIGVDFALKVIRWSDKCNIKL 130

Query: 60  GIWDTAGSERYEAMSRIYYRGAKAAIVCYDLTDSSSFERAKFW 102
            +WD AG ER+ +M+R+YY+ A A IV +DLT  ++++ A  W
Sbjct: 129 QLWDIAGQERFTSMTRVYYKDAHACIVMFDLTQKNTYQNAIRW 1
>34468
          Length = 1502

 Score = 80.1 bits (196), Expect = 6e-16,   Method: Compositional matrix adjust.
 Identities = 58/172 (33%), Positives = 83/172 (48%), Gaps = 6/172 (3%)
 Frame = +1

Query: 4   QRVDVKVVMLGKEYVGKTSLVERYVHDRFLVGPYQNTIGAAFVAKVMCVGDRTVTLGIWD 63
           QR   K++++G   VGKT L  R+   +F     + TIG  F  K + V    + L +WD
Sbjct: 484 QRRIFKIIVIGDSNVGKTCLTYRFCLGKF-PDKTEATIGVDFREKSIQVDSEHLKLQLWD 660

Query: 64  TAGSERY-EAMSRIYYRGAKAAIVCYDLTDSSSFERAKFWVKE--LRSLEEGCQIYLCGT 120
           TAG ER+ ++M + YYR   A +  YD+T  SSFE    W++E    +L +     L G 
Sbjct: 661 TAGQERFRKSMVQHYYRNVHAVVFVYDMTKMSSFENMPAWIEECDRHNLTKYIPRILVGN 840

Query: 121 KSXXXXXXXXXXXVDFHDVQDYADNIKAQLFETSSK---TGQSVDELFQKVA 169
           K            V+ +  Q +AD     LFETS+K       VD +F  VA
Sbjct: 841 KC----DVVERIAVNTNLAQKFADAHNMPLFETSAKDDEKANHVDAIFMTVA 984
>05468
          Length = 1558

 Score = 79.0 bits (193), Expect = 1e-15,   Method: Compositional matrix adjust.
 Identities = 40/101 (39%), Positives = 63/101 (62%), Gaps = 1/101 (0%)
 Frame = -3

Query: 9    KVVMLGKEYVGKTSLVERYVHDRFLVGPYQNTIGAAFVAKVMCV-GDRTVTLGIWDTAGS 67
            K++++G+   GKTS+++RYVH +F    Y+ TIG  F  KV+    D  + L +WD AG 
Sbjct: 1535 KILVIGELGTGKTSIIKRYVH-QFFSQHYRATIGVDFALKVLNWDADTLIRLQLWDIAGQ 1359

Query: 68   ERYEAMSRIYYRGAKAAIVCYDLTDSSSFERAKFWVKELRS 108
            ER+  M+R+YY+ A  A V +D+T +S+F+    W  +L S
Sbjct: 1358 ERFGNMTRVYYKEAVGAFVVFDVTRASTFDAVTKWKNDLDS 1236
>07465
          Length = 1103

 Score = 77.0 bits (188), Expect = 5e-15,   Method: Compositional matrix adjust.
 Identities = 44/153 (28%), Positives = 84/153 (54%)
 Frame = +3

Query: 21  TSLVERYVHDRFLVGPYQNTIGAAFVAKVMCVGDRTVTLGIWDTAGSERYEAMSRIYYRG 80
           +S+++RY    F    Y+ TIG  F+ + + VG   V L +WDTAG E ++A+++ YYRG
Sbjct: 240 SSMIQRYCKGIF-TKDYKKTIGVDFLERQIEVGGEDVRLMLWDTAGQEEFDAITKAYYRG 416

Query: 81  AKAAIVCYDLTDSSSFERAKFWVKELRSLEEGCQIYLCGTKSXXXXXXXXXXXVDFHDVQ 140
           A+A ++ +   D  SFE  + W +++   +E  +I +   ++           V   + +
Sbjct: 417 AQACVLAFSTVDRDSFEALETWKRKVE--DEVGEIGMVIVQN--KIDLIDDAVVRPEEAE 584

Query: 141 DYADNIKAQLFETSSKTGQSVDELFQKVAEDYV 173
           + A  ++ + + TS K   +VDE+F+ +A+ Y+
Sbjct: 585 NLAKKLRLRFYRTSVKENMNVDEVFRYLADKYL 683
>14456
          Length = 1867

 Score = 75.9 bits (185), Expect = 1e-14,   Method: Compositional matrix adjust.
 Identities = 57/192 (29%), Positives = 91/192 (47%), Gaps = 8/192 (4%)
 Frame = -1

Query: 18   VGKTSLVERYVHDRFLVGPYQNTIGAAFVAKVMCVGDRTVTLGIWDTAGSERYEAMSRIY 77
            VGK+SL+ R+V ++F    + +TIG  F+ K + V D T T+ IWDTAG ER++++   +
Sbjct: 1108 VGKSSLMNRFVSNKFDAQSF-HTIGVEFLNKDVVVDDETYTMQIWDTAGQERFKSLRTPF 932

Query: 78   YRGAKAAIVCYDLTDSSSFERAKFWVKEL---RSLEEGC--QIYLCGTKSXXXXXXXXXX 132
            YRGA   ++ + +    SF     W KE      +++G      + G K           
Sbjct: 931  YRGADCCLLTFSVDSMQSFRNLSMWRKEFLYYADIQDGVTFPFVVLGNK-----IDVEGR 767

Query: 133  XVDFHDVQDY-ADNIKAQLFETSSKTGQSVDELFQKVAEDYVSVAAFQVMTEDKG--VDL 189
             V   + + +   N  A  FETS+K   +V++ F    +    V   Q +    G  VDL
Sbjct: 766  QVTNEEARSWCTANSNAPYFETSAKDATNVEKAFLAAVQRLREVEDQQEVKTAHGNTVDL 587

Query: 190  SQKANPYFYSCC 201
            ++ A     SCC
Sbjct: 586  NRAARGKSSSCC 551
>35581
          Length = 364

 Score = 67.4 bits (163), Expect = 4e-12,   Method: Compositional matrix adjust.
 Identities = 31/81 (38%), Positives = 45/81 (55%)
 Frame = +2

Query: 9   KVVMLGKEYVGKTSLVERYVHDRFLVGPYQNTIGAAFVAKVMCVGDRTVTLGIWDTAGSE 68
           K V+LG   VGKT L+ R   D+FL  P  +   A+ +  V        ++ +WDTAG E
Sbjct: 50  KCVLLGDAGVGKTCLLNRLATDKFLDSPLTSLTTASLLTTVTLTSGVMASVDLWDTAGQE 229

Query: 69  RYEAMSRIYYRGAKAAIVCYD 89
           RY +++  YYR  KA ++ YD
Sbjct: 230 RYRSLTSSYYRDTKAVLIVYD 292
>11728
          Length = 635

 Score = 66.2 bits (160), Expect = 8e-12,   Method: Compositional matrix adjust.
 Identities = 40/115 (34%), Positives = 58/115 (50%), Gaps = 1/115 (0%)
 Frame = -1

Query: 8   VKVVMLGKEYVGKTSLVERYVHDRFLVGPYQNTIGAAFVAKVMCVGDRTVTLGIWDTAGS 67
           +K V++G   VGKT L+  Y  + F  G Y  T+   + A VM V  + + LG+WDTAG 
Sbjct: 488 IKCVVVGDGAVGKTCLLISYTTNAF-PGEYIPTVFDNYSANVM-VDSKPINLGLWDTAGQ 315

Query: 68  ERYEAMSRIYYRGAKAAIVCYDLTDSSSFERAKF-WVKELRSLEEGCQIYLCGTK 121
           E Y+ +  + Y      ++C+ L   +SFE  K  W  E+        I L GTK
Sbjct: 314 EDYDRLRPLSYPQTDVFLICFSLISPASFENVKAKWYPEVSHHCPNTPIILVGTK 150
>27191
          Length = 443

 Score = 54.3 bits (129), Expect(2) = 2e-10,   Method: Compositional matrix adjust.
 Identities = 26/96 (27%), Positives = 49/96 (51%)
 Frame = +1

Query: 20  KTSLVERYVHDRFLVGPYQNTIGAAFVAKVMCVGDRTVTLGIWDTAGSERYEAMSRIYYR 79
           KT L++ +   +F  G YQ T+G  +  K+  V    + + +WD +GS  Y  +    Y 
Sbjct: 1   KTCLIKHFCESKFNQG-YQPTVGVDYGFKIQTVNGVDMRVHMWDLSGSNEYLDVRNELYT 177

Query: 80  GAKAAIVCYDLTDSSSFERAKFWVKELRSLEEGCQI 115
           G+ A  + +D++++ SFE    W++E+     G  +
Sbjct: 178 GSDAIFIVFDVSNTPSFEALDSWLREINRFATGSPL 285

 Score = 27.3 bits (59), Expect(2) = 2e-10,   Method: Compositional matrix adjust.
 Identities = 9/21 (42%), Positives = 18/21 (85%)
 Frame = +2

Query: 151 FETSSKTGQSVDELFQKVAED 171
           +ETS+ TG+ VD++FQ++ ++
Sbjct: 380 YETSAATGEGVDDMFQQMLQE 442
>19656
          Length = 428

 Score = 60.8 bits (146), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 38/102 (37%), Positives = 55/102 (53%), Gaps = 2/102 (1%)
 Frame = +3

Query: 8   VKVVMLGKEYVGKTSLVERYVHDRFLVGPYQNTIGAAFVAKVMCVGDRTVTLGIWDTAGS 67
           +K V++G   VGKT L+  Y  + F  G Y  T+   + A VM  G R V LG+WDTAG 
Sbjct: 114 IKCVVVGDGAVGKTCLLISYTTNAF-PGEYIPTVFDNYSANVMVDG-RPVNLGLWDTAGQ 287

Query: 68  ERYEAMSRIYYRGAKAAIVCYDLTDSSSFE--RAKFWVKELR 107
           E Y+ +  + Y      ++C+ +   +SFE  RAK W  E+ 
Sbjct: 288 EDYDRLRPLSYPQTDVFLLCFSVASPASFENIRAK-WYPEVN 410
>33380
          Length = 282

 Score = 59.7 bits (143), Expect = 8e-10,   Method: Compositional matrix adjust.
 Identities = 28/69 (40%), Positives = 41/69 (59%), Gaps = 1/69 (1%)
 Frame = +3

Query: 54  DRTVTLGIWDTAGSERYEAMSRIYYRGAKAAIVCYDLTDSSSFERAKFWVKELRSLE-EG 112
           D+ V L IWDTAG ERY  ++  YYRGA   I+ YD+T+  SF   + W  ++++   + 
Sbjct: 51  DKRVKLQIWDTAGQERYRTITTAYYRGAMGFILMYDVTNEESFNAVQDWCTQIKTYSWDN 230

Query: 113 CQIYLCGTK 121
            Q+ L G K
Sbjct: 231 AQVVLVGNK 257
>01398
          Length = 1421

 Score = 58.5 bits (140), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 34/106 (32%), Positives = 61/106 (57%), Gaps = 2/106 (1%)
 Frame = -2

Query: 68   ERYEAMSRIYYRGAKAAIVCYDLTDSSSFERAKFWVKELRS-LEEGCQIYL-CGTKSXXX 125
            ER+ +++R YYR +   I+ YD+T  S+FE  K W +E R+ +E    I+L  G KS   
Sbjct: 1417 ERFRSITRSYYRNSVGVIIVYDITKRSTFENLKQWYEEARNHIEPHKAIFLVLGHKS--- 1247

Query: 126  XXXXXXXXVDFHDVQDYADNIKAQLFETSSKTGQSVDELFQKVAED 171
                    V   + + +A+    + FETS+K+G +++++F ++A+D
Sbjct: 1246 -DREDARQVTAREGRRFAEMHGLKFFETSAKSGHNIEDVFAQIAKD 1112
>29380
          Length = 853

 Score = 55.5 bits (132), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 34/94 (36%), Positives = 45/94 (47%), Gaps = 1/94 (1%)
 Frame = -2

Query: 81  AKAAIVCYDLTDSSSFERAKFWVKELRSLE-EGCQIYLCGTKSXXXXXXXXXXXVDFHDV 139
           A AAI+ YD+  + +F RA  WVKELR    E   I L G K            V F D 
Sbjct: 852 ASAAIIVYDVNIADTFSRALAWVKELRQQNTESVLIILAGNK---VDLATQHRAVSFEDA 682

Query: 140 QDYADNIKAQLFETSSKTGQSVDELFQKVAEDYV 173
           Q +A        E S+KTG +V+E+F  +A   +
Sbjct: 681 QSFARENGLLFAEVSAKTGMAVNEIFMTLANQLI 580
>13750
          Length = 503

 Score = 55.1 bits (131), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 35/110 (31%), Positives = 55/110 (50%), Gaps = 1/110 (0%)
 Frame = -2

Query: 61  IWDTAGSERYEAMSRIYYRGAKAAIVCYDLTDSSSFERA-KFWVKELRSLEEGCQIYLCG 119
           +WDT G+E Y ++   ++RGA+ A++ YD+T   SF  A   W K L       Q+   G
Sbjct: 379 LWDTGGAETYRSLWVSHFRGAQVALLVYDVTCEWSFLTATTVWRKALMKNIPEAQVIFVG 200

Query: 120 TKSXXXXXXXXXXXVDFHDVQDYADNIKAQLFETSSKTGQSVDELFQKVA 169
           +K+           +     Q +A       FETSS TG++VD +F ++A
Sbjct: 199 SKT----DLEENRVISTERGQAFATQCGYTFFETSSVTGKNVDAVFWEIA 62
>19006
          Length = 568

 Score = 55.1 bits (131), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 34/114 (29%), Positives = 54/114 (47%), Gaps = 1/114 (0%)
 Frame = -2

Query: 9   KVVMLGKEYVGKTSLVERYVHDRFLVGPYQNTIGAAFVAKVMCVGDRTVTLGIWDTAGSE 68
           K+V++G    GKT L+  +  D+F    Y  T+   +VA +  V  + V L +WDTAG E
Sbjct: 432 KLVIVGDGACGKTCLLIVFSKDQFPEV-YVPTVFENYVADIE-VDSKQVELALWDTAGQE 259

Query: 69  RYEAMSRIYYRGAKAAIVCYDLTDSSSFER-AKFWVKELRSLEEGCQIYLCGTK 121
            Y+ +  + Y      ++C+ +    S E   + W  E+R       I L G K
Sbjct: 258 DYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVRHFCPNVPIILVGNK 97
>26536
          Length = 829

 Score = 55.1 bits (131), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 38/131 (29%), Positives = 62/131 (47%), Gaps = 2/131 (1%)
 Frame = +2

Query: 38  QNTIGAAFVAKVMCVGDRTVTLGIWDTAGSERYEAMSRIYYRGAKAAIVCYDLTDSSSFE 97
           + TI    +  +  + +R V+    DTAG E Y +M   Y R     IV Y +TD +SF+
Sbjct: 71  ERTIMLLSLTTMKMMMERRVSWTFLDTAGQEEYSSMREHYTRSGDGFIVVYSVTDVTSFQ 250

Query: 98  RAKFWVKELRSLEEGCQIY--LCGTKSXXXXXXXXXXXVDFHDVQDYADNIKAQLFETSS 155
            A+   + L   ++   I+  LCG K+           V   + +  AD +    FETS+
Sbjct: 251 EAEAVFRWLTRFQDETSIHAVLCGNKTDLTSDRK----VTPEEGRKMADRLGMLYFETSA 418

Query: 156 KTGQSVDELFQ 166
           KTG +V +++ 
Sbjct: 419 KTGDNVSQVYH 451

 Score = 32.7 bits (73), Expect = 0.10,   Method: Compositional matrix adjust.
 Identities = 15/28 (53%), Positives = 18/28 (64%)
 Frame = +2

Query: 6   VDVKVVMLGKEYVGKTSLVERYVHDRFL 33
            D K+VMLG   VGK+SL  R+  D FL
Sbjct: 482 TDYKIVMLGSGGVGKSSLTIRFTQDTFL 565
>01095
          Length = 1745

 Score = 54.3 bits (129), Expect = 4e-08,   Method: Compositional matrix adjust.
 Identities = 31/86 (36%), Positives = 45/86 (52%), Gaps = 1/86 (1%)
 Frame = -1

Query: 86   VCYDLTDSSSFERAKFWVKEL-RSLEEGCQIYLCGTKSXXXXXXXXXXXVDFHDVQDYAD 144
            V YD+T+  +F RAK WVKEL R       I L G K+           V+F + Q YA+
Sbjct: 1745 VVYDITNQDTFGRAKTWVKELQRQASPNIVIALAGNKA----DLANKRMVEFEEAQAYAE 1578

Query: 145  NIKAQLFETSSKTGQSVDELFQKVAE 170
                   ETS+KT  +V+++F  +A+
Sbjct: 1577 ENSLLFMETSAKTAMNVNDIFLAIAK 1500
>01972
          Length = 2359

 Score = 52.4 bits (124), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 30/137 (21%), Positives = 59/137 (43%)
 Frame = +3

Query: 37  YQNTIGAAFVAKVMCVGDRTVTLGIWDTAGSERYEAMSRIYYRGAKAAIVCYDLTDSSSF 96
           Y  T+G      +       +   +WDTAG E++  +   YY   + A++ +D+T   ++
Sbjct: 387 YVATLGVEVHPLLFHTSRGKLKFNVWDTAGQEKFGGLRDGYYIQGQCAVIMFDVTSRVTY 566

Query: 97  ERAKFWVKELRSLEEGCQIYLCGTKSXXXXXXXXXXXVDFHDVQDYADNIKAQLFETSSK 156
           +    W ++L  + E   I LCG K            + FH  ++       Q ++ S+K
Sbjct: 567 KNVPNWHRDLVRVCENIPIVLCGNKVDIKDRKVKAKAIVFHRKKNL------QYYDISAK 728

Query: 157 TGQSVDELFQKVAEDYV 173
           +  + ++ F  +A   V
Sbjct: 729 SNYNFEKPFLWLARKLV 779
>33794
          Length = 779

 Score = 52.0 bits (123), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 35/127 (27%), Positives = 55/127 (43%)
 Frame = -1

Query: 44  AFVAKVMCVGDRTVTLGIWDTAGSERYEAMSRIYYRGAKAAIVCYDLTDSSSFERAKFWV 103
           A+    + +  + V L IWDT+G  R+  + R Y RGA+  I+ YD+T+  SF+    W+
Sbjct: 689 AYKTTTILLEGKRVKLQIWDTSGQGRFCTIIRSYSRGAQGIILVYDITNKWSFDGIDRWL 510

Query: 104 KELRSLEEGCQIYLCGTKSXXXXXXXXXXXVDFHDVQDYADNIKAQLFETSSKTGQSVDE 163
           KE+     G    L G +            V     + YA       FE S     ++ E
Sbjct: 509 KEVEEHAPGIPKVLVGNR----LHLAYKRQVAAKQAETYASRNNMSCFEISPLCDFNIRE 342

Query: 164 LFQKVAE 170
            F ++A 
Sbjct: 341 SFCELAR 321
>32723
          Length = 384

 Score = 49.3 bits (116), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 29/104 (27%), Positives = 54/104 (51%), Gaps = 2/104 (1%)
 Frame = +2

Query: 68  ERYEAMSRIYYRGAKAAIVCYDLTDSSSFERAKFWVKELRSLEEGCQI--YLCGTKSXXX 125
           ER+ ++++ YYR A A I+ YD+    S+E    W+ E+  L  G ++  +L G K    
Sbjct: 5   ERFRSITQSYYRSANALILVYDVCSQQSYESLPQWIHEI-ELYAGTKVLAFLVGNK---- 169

Query: 126 XXXXXXXXVDFHDVQDYADNIKAQLFETSSKTGQSVDELFQKVA 169
                   +  H  +++A+  + +  ETS+K   +V++LF  +A
Sbjct: 170 IDQTDKREIPTHIGKEFAERYEMRFLETSAKEADNVEKLFSTIA 301
>34359
          Length = 1042

 Score = 47.8 bits (112), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 31/131 (23%), Positives = 56/131 (42%)
 Frame = +3

Query: 7   DVKVVMLGKEYVGKTSLVERYVHDRFLVGPYQNTIGAAFVAKVMCVGDRTVTLGIWDTAG 66
           + K+V++G  +    ++V+R+V        Y  T+G              +   +WDTAG
Sbjct: 51  NFKLVLVGGRWEWANNIVKRHVTGS*--KKYVATLGVEVHPLQFNTSRGLLRFNVWDTAG 224

Query: 67  SERYEAMSRIYYRGAKAAIVCYDLTDSSSFERAKFWVKELRSLEEGCQIYLCGTKSXXXX 126
            E++  +   YY     AI+ +D+T   +++    W ++L  + E   I LCG K     
Sbjct: 225 QEKFGGLRDGYYIQGTCAIIMFDVTSRVTYKNVPNWHRDLVRVCENIPIVLCGNKVDIKD 404

Query: 127 XXXXXXXVDFH 137
                  + FH
Sbjct: 405 RKVKAKAIVFH 437
>11257
          Length = 1102

 Score = 47.0 bits (110), Expect = 6e-06,   Method: Compositional matrix adjust.
 Identities = 26/86 (30%), Positives = 42/86 (48%)
 Frame = -2

Query: 21   TSLVERYVHDRFLVGPYQNTIGAAFVAKVMCVGDRTVTLGIWDTAGSERYEAMSRIYYRG 80
            TSL+    HDR  V P+++ +          V   T T+ IWDTAG ERY+++   +YRG
Sbjct: 1101 TSLMPSLPHDRRGV-PHKDVV----------VDGETFTMQIWDTAGQERYKSLRTPFYRG 955

Query: 81   AKAAIVCYDLTDSSSFERAKFWVKEL 106
                ++ + + +  S +    W  E 
Sbjct: 954  TDCCLLTFSVDNLKSLQSLSDWYDEF 877
>30760
          Length = 596

 Score = 45.8 bits (107), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 39/160 (24%), Positives = 69/160 (43%), Gaps = 3/160 (1%)
 Frame = -1

Query: 9   KVVMLGKEYVGKTSLVERYVHDR-FLVGPYQNTIGAAFVAKVMCVGDR--TVTLGIWDTA 65
           K ++ G   VGK+S+ + +  D       Y  T G   + K++ + D    V L ++D+A
Sbjct: 524 KCIVTGDSGVGKSSICQVFHSDSAHFPKNYSMTTGVEVLVKLVNIPDSRDQVELYLFDSA 345

Query: 66  GSERYEAMSRIYYRGAKAAIVCYDLTDSSSFERAKFWVKELRSLEEGCQIYLCGTKSXXX 125
           G E +      ++      +V YD+TD +SF     W++ +R+ +    I   G      
Sbjct: 344 GKEIFSENVTKFWDQPSVVMVVYDVTDETSFSGCVRWLERVRAAKPNTVIP--GVLVANK 171

Query: 126 XXXXXXXXVDFHDVQDYADNIKAQLFETSSKTGQSVDELF 165
                   V   + +D A +   + FE S+K  Q+ D  F
Sbjct: 170 TDLDERRRVSRKEGKDLAQSHGLEYFECSAKEMQNTDTPF 51
>31291
          Length = 446

 Score = 44.7 bits (104), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 33/120 (27%), Positives = 52/120 (43%), Gaps = 10/120 (8%)
 Frame = -1

Query: 59  LGIWDTAGSERYEAMSRIYYRGAKAAIVCYDLTDSSSFERAKF-WVKELRSLEEGCQIYL 117
           L +WDTAG E Y+ +  + Y      ++ + L   +S +  K  W  E+R  +    I L
Sbjct: 446 LQLWDTAGQEDYDRLRPLAYPNTDVFMLXFSLMSEASMKNVKVKWYPEIRHHDPHVPIVL 267

Query: 118 CGTK--------SXXXXXXXXXXXVDFHDVQDYADNIKAQL-FETSSKTGQSVDELFQKV 168
            GTK        +           V  +   D A  IKA+  FE SSKT +++   F++ 
Sbjct: 266 VGTKLDLRQDKEAVRKLRSSRQDPVSSNQGNDLAKAIKAKRYFECSSKTQENLKTAFEET 87
>00552
          Length = 455

 Score = 40.8 bits (94), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 16/47 (34%), Positives = 26/47 (55%)
 Frame = -3

Query: 60  GIWDTAGSERYEAMSRIYYRGAKAAIVCYDLTDSSSFERAKFWVKEL 106
           GIWDTAG ERY+++   +YRG    ++ + + +  S +    W  E 
Sbjct: 150 GIWDTAGQERYKSLRTPFYRGTDCCLLTFSVDNLKSLQSLSDWYDEF 10

 Score = 37.4 bits (85), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 21/52 (40%), Positives = 33/52 (63%)
 Frame = -1

Query: 8   VKVVMLGKEYVGKTSLVERYVHDRFLVGPYQNTIGAAFVAKVMCVGDRTVTL 59
           +KVV+LG   VGK+SL+ R+V ++F    + +TIG  F+ K + V   T T+
Sbjct: 443 LKVVLLGDGGVGKSSLMNRFVSNKFDAQSF-HTIGVEFLTKDVVVDGETFTM 291
>14119
          Length = 602

 Score = 40.0 bits (92), Expect = 6e-04,   Method: Compositional matrix adjust.
 Identities = 27/80 (33%), Positives = 37/80 (46%), Gaps = 1/80 (1%)
 Frame = +1

Query: 95  SFERAKFWVKELRSLEEG-CQIYLCGTKSXXXXXXXXXXXVDFHDVQDYADNIKAQLFET 153
           +F RA  WVKELR    G   I L G K+           V   D + +A++      E 
Sbjct: 1   TFNRALAWVKELRQQNAGSVLIVLAGNKA---DLASEHRAVSADDARTFAEDNGLIFAEV 171

Query: 154 SSKTGQSVDELFQKVAEDYV 173
           S+KTG +V E+F  +A   V
Sbjct: 172 SAKTGMAVSEVFMTIAHKLV 231
>14775
          Length = 380

 Score = 38.5 bits (88), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 28/109 (25%), Positives = 44/109 (40%)
 Frame = -2

Query: 61  IWDTAGSERYEAMSRIYYRGAKAAIVCYDLTDSSSFERAKFWVKELRSLEEGCQIYLCGT 120
           +WDT G+E Y ++   ++RGA+ A++ YD+T                  E G        
Sbjct: 256 LWDTGGAETYRSLWVSHFRGAQVALLVYDVT-----------------CERG-------- 152

Query: 121 KSXXXXXXXXXXXVDFHDVQDYADNIKAQLFETSSKTGQSVDELFQKVA 169
                              Q +A       FETSS TG++VD +F ++A
Sbjct: 151 -------------------QAFATQCGYTFFETSSVTGKNVDAVFWEIA 62
>12339
          Length = 578

 Score = 35.8 bits (81), Expect = 0.012,   Method: Compositional matrix adjust.
 Identities = 13/39 (33%), Positives = 24/39 (61%)
 Frame = -2

Query: 68  ERYEAMSRIYYRGAKAAIVCYDLTDSSSFERAKFWVKEL 106
           ER++++   +YRGA   I+ YD+T+  +F+    W +E 
Sbjct: 574 ERFQSLGVAFYRGADCCILVYDVTEXKTFDSLDSWQREF 458
>33605
          Length = 888

 Score = 35.0 bits (79), Expect = 0.019,   Method: Compositional matrix adjust.
 Identities = 20/92 (21%), Positives = 40/92 (43%)
 Frame = +1

Query: 1   MSGQRVDVKVVMLGKEYVGKTSLVERYVHDRFLVGPYQNTIGAAFVAKVMCVGDRTVTLG 60
           M  +  +V+++MLG +  GKT++++++       G   +TI       +  +  R   L 
Sbjct: 478 MKQKEKEVRLLMLGLDNAGKTTILKKF------NGEDIDTISPTLGFNIKTLEHRGFKLN 639

Query: 61  IWDTAGSERYEAMSRIYYRGAKAAIVCYDLTD 92
           +WD  G +   +  R Y+      +   D  D
Sbjct: 640 VWDVGGQQSLRSYWRNYFESTDGLVWVVDSAD 735
>10708
          Length = 2775

 Score = 35.0 bits (79), Expect = 0.022,   Method: Compositional matrix adjust.
 Identities = 13/42 (30%), Positives = 21/42 (50%)
 Frame = -2

Query: 57   VTLGIWDTAGSERYEAMSRIYYRGAKAAIVCYDLTDSSSFER 98
            V L +WDTAG E Y+ +  + Y      ++C+ +    S E 
Sbjct: 2723 VELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLEN 2598
>13745
          Length = 1045

 Score = 34.3 bits (77), Expect = 0.037,   Method: Compositional matrix adjust.
 Identities = 13/39 (33%), Positives = 23/39 (58%)
 Frame = +2

Query: 68  ERYEAMSRIYYRGAKAAIVCYDLTDSSSFERAKFWVKEL 106
           ER++++   +YRGA   ++ YD+T  +SF+    W  E 
Sbjct: 5   ERFQSLGVAFYRGADCCVLVYDVTAPNSFKNLDSWRDEF 121
>10862
          Length = 2896

 Score = 30.4 bits (67), Expect(2) = 0.078,   Method: Compositional matrix adjust.
 Identities = 11/42 (26%), Positives = 18/42 (42%)
 Frame = -3

Query: 59   LGIWDTAGSERYEAMSRIYYRGAKAAIVCYDLTDSSSFERAK 100
              +WD  G ++   + R YY G +  I   D  D    + A+
Sbjct: 2480 FNVWDVGGQDKIRPLWRHYYTGTQGLIFVVDCADRDRIDEAR 2355

 Score = 21.6 bits (44), Expect(2) = 0.078,   Method: Compositional matrix adjust.
 Identities = 7/18 (38%), Positives = 15/18 (83%)
 Frame = -1

Query: 7    DVKVVMLGKEYVGKTSLV 24
            +++++MLG +  GKT+L+
Sbjct: 2617 EMRILMLGLDAAGKTTLL 2564
>00858
          Length = 1658

 Score = 32.7 bits (73), Expect = 0.10,   Method: Compositional matrix adjust.
 Identities = 37/153 (24%), Positives = 67/153 (43%), Gaps = 7/153 (4%)
 Frame = -2

Query: 20   KTSLVERYVHDRFLVGPYQNTIGAAFVAKVMCVGDRTVTLGIWDTAGSERYEAMSRIYYR 79
            K++L  +   + F V  Y  T   +   +V+  G+ T  L I DTAG E   AM     R
Sbjct: 1552 KSALTIQLXQNHF-VEEYDPTXEDSXRKQVVIDGE-TCLLDILDTAGQEEXSAMRDQCMR 1379

Query: 80   GAKAAIVCYDLTDSSSFERAKFWVKELRSLEEGCQI--YLCGTKSXXXXXXXXXXXVDFH 137
              +  +  + + +  SFE    + ++++ +++  ++   L G K            +   
Sbjct: 1378 TGEGFLCVFAVXNLKSFEDINQYREQIKRVKDADEVPMVLVGNK----------VDLPIR 1229

Query: 138  DVQDYADNIKAQLF-----ETSSKTGQSVDELF 165
            +V+       A+L+     ETS+KT Q VD+ F
Sbjct: 1228 NVEQRQGKHMAELYHIPYVETSAKTRQGVDDAF 1130
>12443
          Length = 837

 Score = 31.6 bits (70), Expect = 0.23,   Method: Compositional matrix adjust.
 Identities = 31/126 (24%), Positives = 57/126 (45%), Gaps = 8/126 (6%)
 Frame = -3

Query: 4   QRVDVKVVMLGKEYVGKTSLVERYVHDRFLVG----PYQNTIGAAFVAKVMCVGDRTV-T 58
           + V+ KV+++GK  VGKTS V +   +   +     P   T    +  K+  +G   +  
Sbjct: 592 EEVNYKVMLVGKTGVGKTSTVAKLTGNDIPLTHNETPGLQTSHLYWPGKIKHLGKTVLFQ 413

Query: 59  LGIWDTAGS--ERYEAMSRIYYRGAKAAIVCYDLTDSSSFERAKFWVKELRSLEEG-CQI 115
           + ++D   +  +RY+ +      G    +  +   D  SF+     +    +LE+G C+I
Sbjct: 412 IQLFDAGETALKRYDHILPACQDGVDGIMFLFSFVDKGSFDEIPQLLTRFTTLEDGICKI 233

Query: 116 YLCGTK 121
            L GTK
Sbjct: 232 AL-GTK 218
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|94405856|ref|XP_148904.8| PREDICTED: oxysterol
binding protein isoform 1 [Mus musculus]
         (966 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

34077                                                                 120   2e-27
13073                                                                  75   1e-13
22811                                                                  72   1e-12
18916                                                                  68   2e-11
13952                                                                  37   0.045
29521                                                                  30   4.3  
21814                                                                  30   6.2  
>34077
          Length = 483

 Score =  120 bits (301), Expect = 2e-27,   Method: Compositional matrix adjust.
 Identities = 64/161 (39%), Positives = 81/161 (50%)
 Frame = +3

Query: 806 DEKMDCFKVQAASGENGGDARQRGHEAEDSRVMLWKRNPLPKNAENMYYFSELALTLNAW 865
           D++++   V   SG   G     G        + WKR P P  AE  Y F+ LA  LN  
Sbjct: 3   DDQIEIAPVLHTSGSADGPTYTTGE-----YRIAWKRRPCPPEAEKFYNFTTLACQLNEP 167

Query: 866 EGGTAPTDSRLRPDQRLMENGRWDEANAEKQRLEEKQRLSXXXXXXXXXXXTEDGTPHDP 925
           E G APTDSRLRPDQRLME G W+ +N EK     KQR               +G P+  
Sbjct: 168 EEGVAPTDSRLRPDQRLMEEGVWEASNKEKLAPRGKQRTKRREREAEAELAAAEGRPYPA 347

Query: 926 YKALWFERKKDPVTRELTHIYSGEYWECKEKQDWGSCPDIF 966
           Y+ +WFERKK     +  H++   YWE K  QDW  CP+I+
Sbjct: 348 YEPVWFERKKQQDNEDFVHVFKNTYWEAKAAQDWSGCPEIY 470
>13073
          Length = 490

 Score = 75.5 bits (184), Expect = 1e-13,   Method: Compositional matrix adjust.
 Identities = 39/88 (44%), Positives = 57/88 (64%), Gaps = 2/88 (2%)
 Frame = -2

Query: 252 GWLFKWTNYIKGYQRRWFVLSNGLLSYYRSKAEMRHTCRGTINLATANITVE--DSCNFI 309
           G L KWTNY+ G+Q R+ VL +G LSYY+S+ E    CRG ++L  A +T    D C F 
Sbjct: 264 GTLSKWTNYLHGWQDRYIVLKDGTLSYYKSEDETAFGCRGAVSLTRATVTPHQFDECRFD 85

Query: 310 ISNGGAQTYHLKASSEVERQRWVTALEL 337
           +S   +  ++L++S+  ERQRWV ++EL
Sbjct: 84  VSVNDS-VWYLRSSTLEERQRWVDSVEL 4
>22811
          Length = 780

 Score = 72.0 bits (175), Expect = 1e-12,   Method: Compositional matrix adjust.
 Identities = 58/193 (30%), Positives = 84/193 (43%), Gaps = 4/193 (2%)
 Frame = -2

Query: 768 CNLKFVPYSYFSRDVARKVTGEVTDPSGKVHFALLGTWDEKMDCFKVQAASGENGGDARQ 827
           C L F   S        +V G +    GK+   L G W+E   C                
Sbjct: 770 CKLTFTKGSNSYSSKRYEVYGSIQTSEGKLVHNLFGKWNEAFFC---------------- 639

Query: 828 RGHEAEDSRVMLWKRNPLPKNAENMYYFSELALTLNAWEGGTA----PTDSRLRPDQRLM 883
            GH A  +R  +W+   +P++ E  Y F+  A+ LN  +   +    PTD+R RPDQR M
Sbjct: 638 -GH-ASSARC-IWRPGSMPEDHELYYGFTRFAIELNELDMEQSRFVPPTDTRFRPDQRAM 468

Query: 884 ENGRWDEANAEKQRLEEKQRLSXXXXXXXXXXXTEDGTPHDPYKALWFERKKDPVTRELT 943
           E GR  EA +EK RLE  QR              E G    P   LWF +K   ++ +  
Sbjct: 467 EEGRIQEAESEKNRLENLQR-------ERRKKTEELGHDQSP---LWFSKKM--LSGKEV 324

Query: 944 HIYSGEYWECKEK 956
           + Y+ +YWE +++
Sbjct: 323 YEYNAKYWEARKE 285
>18916
          Length = 574

 Score = 67.8 bits (164), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 36/87 (41%), Positives = 53/87 (60%), Gaps = 2/87 (2%)
 Frame = -3

Query: 252 GWLFKWTNYIKGYQRRWFVLSNGLLSYYRSKAEMRHTCRGTINLATANITVE--DSCNFI 309
           G L KWTNY+ G+Q R+ VL +G LSYY+S+ E    CRG ++LA A +T    D C   
Sbjct: 404 GTLSKWTNYLHGWQDRYIVLKDGTLSYYKSEDETAFGCRGAVSLARAVVTPHQFDECRXD 225

Query: 310 ISNGGAQTYHLKASSEVERQRWVTALE 336
           +S   +  ++L+ +S  ER +WV  +E
Sbjct: 224 VSVNDS-VWYLRGASPEERLQWVDTIE 147
>13952
          Length = 577

 Score = 36.6 bits (83), Expect = 0.045,   Method: Compositional matrix adjust.
 Identities = 14/35 (40%), Positives = 23/35 (65%)
 Frame = -3

Query: 250 REGWLFKWTNYIKGYQRRWFVLSNGLLSYYRSKAE 284
           +EGWL K     K ++RRWF+L++  L Y++  A+
Sbjct: 416 KEGWLMKQGGRYKNWKRRWFILNDNCLYYFQYTAD 312
>29521
          Length = 903

 Score = 30.0 bits (66), Expect = 4.3,   Method: Compositional matrix adjust.
 Identities = 26/84 (30%), Positives = 37/84 (44%), Gaps = 6/84 (7%)
 Frame = +1

Query: 267 RWFVL-SNGLLSYYRSKAEMRHTCRGTINLATANITV-----EDSCNFIISNGGAQTYHL 320
           R+F+L  +  L YY+ + +      G I LA    +       D C F     GA+TY+ 
Sbjct: 1   RYFILRQDSCLYYYKQREDSDPL--GAIPLAGYTFSRHLDSGRDFC-FKAEKYGARTYYF 171

Query: 321 KASSEVERQRWVTALELAKAKAVK 344
              S  +   WV AL  A AK+ K
Sbjct: 172 MTESRDDMTEWVGALSEAAAKSKK 243
>21814
          Length = 415

 Score = 29.6 bits (65), Expect = 6.2,   Method: Composition-based stats.
 Identities = 16/46 (34%), Positives = 24/46 (52%)
 Frame = +3

Query: 293 INLATANITVEDSCNFIISNGGAQTYHLKASSEVERQRWVTALELA 338
           +  A   I  ED   F I+    +T+H +A    ER+RW+ AL+ A
Sbjct: 12  LKCAIIGIDDEDDSTFTITVD-HKTFHFQARDGDERERWINALQRA 146
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|115511010|ref|NP_032689.2| myosin VIIa [Mus musculus]
         (2177 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

17228                                                                 121   3e-27
25922                                                                 115   3e-25
29103                                                                 110   6e-24
01284                                                                  62   2e-09
30605                                                                  58   5e-08
06522                                                                  31   6.8  
>17228
          Length = 487

 Score =  121 bits (303), Expect = 3e-27,   Method: Compositional matrix adjust.
 Identities = 56/161 (34%), Positives = 90/161 (55%)
 Frame = +3

Query: 1934 WIKKARPIKDGIVPSLTYQVFFMKKLWTTTVPGKDPMADSIFHYYQELPKYLRGYHKCTR 1993
            W +  R    G  P+    +  +KK+W   +PG+D  AD  FH+ QE+P +LRGYHK T 
Sbjct: 3    WHRHRRNSSTGSTPTPGPSLVMLKKIWVNVIPGEDIEADKHFHFPQEVPNFLRGYHKVTG 182

Query: 1994 EEVLQLGALIYRVKFEEDKSYFPSIPKLLRELVPQDLIRQVSPDDWKRSIVAYFNKHAGK 2053
            EE +++ AL+YRV+F +D ++F     +   ++P+        DD K+++ A +    G 
Sbjct: 183  EEAVKMAALLYRVRFSQDATHFTKFSDIAPAILPRGFPETGLLDDVKKAVEAEYKNSTGS 362

Query: 2054 SKEEAKLAFLKLIFKWPTFGSAFFEVKQTTEPNFPEILLIA 2094
            S +  +  FL++   WPT+G  FFEVKQ    + P+  L+A
Sbjct: 363  SPDSVRERFLQMAVSWPTYGCVFFEVKQRMMKSLPKYCLLA 485
>25922
          Length = 422

 Score =  115 bits (287), Expect = 3e-25,   Method: Composition-based stats.
 Identities = 57/136 (41%), Positives = 85/136 (62%), Gaps = 2/136 (1%)
 Frame = -2

Query: 366 LMSCLTSRTLITRGETVSTPLSREQALDVRDAFVKGIYGRLFVWIVEKINAAIYKPPPLE 425
           L   L  RT+  +G+ V+T LS  ++   RDA  K +Y R+F W+V +IN +I      +
Sbjct: 409 LAHALMHRTVAVKGDMVTTDLSVSESSYARDALCKALYSRMFSWLVHRINDSI------K 248

Query: 426 VKNSRRS--IGLLDIFGFENFTVNSFEQLCINFANEHLQQFFVRHVFKLEQEEYDLESID 483
           V+ ++R+  +G+LDI+GFE F  NSFEQ  IN+ NE LQQ F+    K EQEEY  E I+
Sbjct: 247 VRGAQRTKVMGVLDIYGFEVFENNSFEQFIINYCNEKLQQIFIELTLKEEQEEYIKEGIE 68

Query: 484 WLHIEFTDNQEALDMI 499
           W+H+E+ +N    ++I
Sbjct: 67  WIHVEYFNNAVICELI 20
>29103
          Length = 431

 Score =  110 bits (275), Expect = 6e-24,   Method: Compositional matrix adjust.
 Identities = 52/132 (39%), Positives = 81/132 (61%), Gaps = 1/132 (0%)
 Frame = +3

Query: 1951 YQVFFM-KKLWTTTVPGKDPMADSIFHYYQELPKYLRGYHKCTREEVLQLGALIYRVKFE 2009
            YQ++   +K+W    PG DP AD  FH+ QE+P ++RGYH+C REEV++L AL+YR +F 
Sbjct: 21   YQIWSC*RKIWVNVNPGDDPQADKHFHFPQEVPNFVRGYHQCPREEVIRLAALLYRTRFG 200

Query: 2010 EDKSYFPSIPKLLRELVPQDLIRQVSPDDWKRSIVAYFNKHAGKSKEEAKLAFLKLIFKW 2069
             D ++F    ++   L+P+  +   S D  K+ + A + +  G S++EA+  FL++   W
Sbjct: 201  SDVTHFSRFSEVAATLLPRGFV-AGSGDHTKKEVEAEYKRSEGISQDEARARFLRVAVTW 377

Query: 2070 PTFGSAFFEVKQ 2081
            PT     FEVKQ
Sbjct: 378  PTVRVCLFEVKQ 413
>01284
          Length = 1603

 Score = 62.4 bits (150), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 39/122 (31%), Positives = 65/122 (53%), Gaps = 1/122 (0%)
 Frame = +2

Query: 609 TLSSQFKRSLELLMRTLGACQPFFVRCIKPNEFKKPMLFDRHLCVRQLRYSGMMETIRIR 668
           ++ ++F++ L +LM  L +    F+RCIKPN      LF+    + QL+ +GM+  + + 
Sbjct: 17  SVGTKFRKQLLVLMDKLKSTGTNFIRCIKPNVKMVDHLFEGANILSQLQCAGMVSVLELM 196

Query: 669 HAGYPIRYSFVEFVERYRVLLPGVKPAYKQGDLRGTCQRMAEAVLGTHD-DWQIGKTKIF 727
             G+P R  F E    Y+  LP   P   + D R  C+ + +A LG  D D++ G TK+F
Sbjct: 197 QQGFPSRTPFSELYNMYKKYLP---PELSRLDPRLFCKSLFKA-LGLDDKDFKFGLTKVF 364

Query: 728 LK 729
            +
Sbjct: 365 FR 370
>30605
          Length = 336

 Score = 57.8 bits (138), Expect = 5e-08,   Method: Composition-based stats.
 Identities = 37/109 (33%), Positives = 57/109 (52%), Gaps = 5/109 (4%)
 Frame = -3

Query: 294 DSQEYANIRSAMKVLMFTDTENWEISKLLAAILHMGNLQYEARTFENLDACEVL--FSPS 351
           D +++     AM  +  +D +   I  L+AA+LH+GN+ +E    +    C+VL     S
Sbjct: 328 DVRDFKVCDEAMTRMGVSDADKMAIFMLVAAVLHLGNIAFEDDHDDTKGGCKVLEEAEDS 149

Query: 352 LATAASLLEVNPPDLMSCLTSRTLIT---RGETVSTPLSREQALDVRDA 397
           LATAA LL V+  +L   LTSR + +   +G  +  PL   +A   RDA
Sbjct: 148 LATAAVLLGVDKMELRDSLTSRIMQSGGIKGSAIKVPLKPSEASSARDA 2
>06522
          Length = 536

 Score = 30.8 bits (68), Expect = 6.8,   Method: Composition-based stats.
 Identities = 15/42 (35%), Positives = 22/42 (52%)
 Frame = -2

Query: 1300 SLYIALFDKVSSLGSGSDHVMDAISQCEQYAKEQGAQERNAP 1341
            ++YIAL        S   H+M  I+ C +Y  EQG ++R  P
Sbjct: 469  NIYIALRGTELLHXSQQQHIMHXITFCSEYI*EQGGRQRQLP 344
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|24418933|ref|NP_722502.1| acyl-CoA synthetase family
member 2 [Mus musculus]
         (615 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

20450                                                                 119   3e-27
26510                                                                  85   7e-17
14024                                                                  85   7e-17
00262                                                                  74   2e-13
13327                                                                  71   1e-12
02291                                                                  66   4e-11
37217                                                                  61   1e-09
14264                                                                  50   4e-06
34113                                                                  47   3e-05
19187                                                                  44   3e-04
25970                                                                  41   0.001
03756                                                                  39   0.008
36553                                                                  33   0.25 
22123                                                                  31   1.3  
16054                                                                  30   2.6  
>20450
          Length = 775

 Score =  119 bits (299), Expect = 3e-27,   Method: Compositional matrix adjust.
 Identities = 65/185 (35%), Positives = 102/185 (55%), Gaps = 2/185 (1%)
 Frame = -3

Query: 431 GSVGRIMPHTEAQIVNVETGELTNLNVPGELYIRGYCVMQGYWGEPQKTFETVGQDKWYR 490
           GS G   P+ E ++++ ETG+   +N  G+LY RG  +M+GY   PQ T +T+    W +
Sbjct: 635 GSCGFPTPNAEFKVIDSETGKCLGVNQAGDLYKRGPLIMRGYHKNPQATADTIDAQGWLK 456

Query: 491 TGDIALMDEQGFCKIVGRSKDMIIRGGENIYPAELEDFFLKHPQVQEAQVVGVKDERMGE 550
           TGD+   D  GF  IV R K++I   GE + PA LED  L HP + +A V+G  D+  GE
Sbjct: 455 TGDVGQFDSNGFLYIVDRKKELIKYKGEQVAPAMLEDVLLSHPGISDAAVIGRPDDMAGE 276

Query: 551 -EICACIRLKSGETTTAEEIKAF-CKGKISHFKIPRYIVFVEGYPLTISGKIQKFKLREQ 608
             +   ++   G   T +E+K F  K   S+ ++   + F +  P + SGKI +  LR++
Sbjct: 275 LPMAFVVKATGGNDLTEKEVKDFVAKNVASYMQLRGGVQFRKEIPKSPSGKILRRLLRDE 96

Query: 609 MEQHL 613
           ++  L
Sbjct: 95  LKLQL 81
>26510
          Length = 1692

 Score = 85.1 bits (209), Expect = 7e-17,   Method: Compositional matrix adjust.
 Identities = 50/134 (37%), Positives = 70/134 (52%)
 Frame = +2

Query: 448  ETGELTNLNVPGELYIRGYCVMQGYWGEPQKTFETVGQDKWYRTGDIALMDEQGFCKIVG 507
            ETG    +   GE  + G   M GY    Q T + + +D W  TGD+  M E G   I  
Sbjct: 1244 ETGRAVGVGELGEYCMDGPQKMLGYLHNQQATDDMIDRDGWLHTGDLGYMREDGMIIIED 1423

Query: 508  RSKDMIIRGGENIYPAELEDFFLKHPQVQEAQVVGVKDERMGEEICACIRLKSGETTTAE 567
            R K++I   G  + PAELE   L HP VQ+A V+G+ D+  GE   A + LK   T +A+
Sbjct: 1424 RLKELIKYKGFQVPPAELESLLLSHPAVQDAGVIGIPDQEAGELPRAYVVLKPTVTASAK 1603

Query: 568  EIKAFCKGKISHFK 581
            +I AF + K++  K
Sbjct: 1604 DIMAFVEDKVNPSK 1645

 Score = 73.2 bits (178), Expect = 3e-13,   Method: Compositional matrix adjust.
 Identities = 72/278 (25%), Positives = 119/278 (42%), Gaps = 2/278 (0%)
 Frame = +1

Query: 103 AQLKEEVDKAASGLLSIGLRKGDRLGMWGPNSYAWVLIQLATAQAGIILVSVNPAYQSSE 162
           A+ +  + + ASGL   G +KGD +     N   + ++ LA A  G+I+   NP Y  +E
Sbjct: 301 AK*RTTLRRVASGLHKRGYKKGDVIVTCTVNLPEFSILILAAAYLGVIVSPANPTYTPAE 480

Query: 163 LEYVLRKVG-CKGIVFPKQFKTQQYYDILKQVCPELEKAQPGALKSERLP-DLTTVISVD 220
           L ++L   G C     P             Q+ P ++     A+    LP  +  V +  
Sbjct: 481 LSHMLTHNGACAMFTIP-------------QLVPLVQ----AAIADPDLPHSVKEVYTFG 609

Query: 221 APLPGTLLLDDIVAAGGKEQNLAQLRYNQRFLSCYDPINIQFTSGTTGNPKGATLSHHNI 280
               GT     +++  GK         N       D + + ++SGTTG PKG  LSH NI
Sbjct: 610 HAEEGTEFFQALMSDDGKS-----FPDNIDINPSTDVLFLPYSSGTTGLPKGVMLSHRNI 774

Query: 281 VNNSMLIGQRLKMPTKTAEELRLVLPSPLYHCLGSVGGTMVSMMHGATLLLSSPSFNGKK 340
           V N +    + +    T  E R +   P +H  G       ++  GA  L++ P F  + 
Sbjct: 775 VANIL----QFRELANTQPEDRTLGLLPFFHIYGLTCVQFGTLYDGAE-LVTVPRFEPEL 939

Query: 341 ALEAISREKGTLLYGTPTMFVDILNQPDFSSYDFTSIR 378
            L+++   K TLL   P + + +   P  S +D ++I+
Sbjct: 940 FLKSLHDRKITLLQAVPPVVLFLARHPMVSQFDLSNIK 1053
>14024
          Length = 655

 Score = 85.1 bits (209), Expect = 7e-17,   Method: Compositional matrix adjust.
 Identities = 56/171 (32%), Positives = 92/171 (53%), Gaps = 2/171 (1%)
 Frame = +3

Query: 374 FTSIRGGVIAGSPAPPELIRAIINKMNMKELVVVYGTTENSPVTFMNFPEDTLEQKAGSV 433
           F  +   V A +P  PE  +  ++ ++MK ++  +G +E S    +  P+ TL     S+
Sbjct: 27  FDRVISLVSAAAPMSPETKKYFLS-LDMK-ILDAFGMSETSGCHTLCQPDSTL---LNSI 191

Query: 434 GRIMPHTEAQIVNVETGELTNLNVPGELYIRGYCVMQGYWGEPQKTFETVGQDKWYRTGD 493
           G+ +P  E++I+N       + N  GEL IRG  V  GY    +KT E++  D W  +GD
Sbjct: 192 GKSLPGCESKIIN------QDANGHGELCIRGRHVFMGYISNKEKTEESLDDDCWLHSGD 353

Query: 494 IALMDEQGFCKIVGRSKDMIIR-GGENIYPAELEDFFLKHPQ-VQEAQVVG 542
           +A +D++G+  + GR K++II  GGENI P  +E+   K    +  A +VG
Sbjct: 354 LAYIDDKGYVCLTGRLKELIITAGGENIPPVHIENIIKKELDGISNAFLVG 506
>00262
          Length = 1036

 Score = 73.6 bits (179), Expect = 2e-13,   Method: Compositional matrix adjust.
 Identities = 45/166 (27%), Positives = 75/166 (45%), Gaps = 9/166 (5%)
 Frame = -1

Query: 459 GELYIRGYCVMQGYWGEPQKTFETVGQDKWYRTGDIALMDEQGFCKIVGRSKDMIIRGGE 518
           GE+  +   +   Y    +   ++   D W+RT D+   ++      +GR  D I RG  
Sbjct: 910 GEIIAKSPALYSRYIDNDEAAKKSFTPDGWFRTDDMGCFNQDKHIIHLGRRTDAITRGAY 731

Query: 519 NIYPAELEDFFLKHPQVQEAQVVGVKDERMGEEICACI---------RLKSGETTTAEEI 569
             YP  LE    + P V++  VV V D  +  EICAC+           ++   T A+ +
Sbjct: 730 LCYPGWLETLLRRSPSVRDVCVVPVADPVLHHEICACVIPNDDPPVADFEASLRTFADSL 551

Query: 570 KAFCKGKISHFKIPRYIVFVEGYPLTISGKIQKFKLREQMEQHLKL 615
               +G+  H   P+Y V ++ +PLT +GKI +  +    E+ L L
Sbjct: 550 LLTQEGEAQHMA-PKYYVILQSFPLTPTGKIHRKDVIAIAEKQLGL 416
>13327
          Length = 549

 Score = 71.2 bits (173), Expect = 1e-12,   Method: Composition-based stats.
 Identities = 41/128 (32%), Positives = 67/128 (52%), Gaps = 2/128 (1%)
 Frame = +3

Query: 488 WYRTGDIALMDEQGFCKIVGRSKDMIIRGGENIYPAELEDFFLKHPQVQEAQVVGVKDER 547
           W  +GD+   D  GF  IV R K++I    E + PA LED  L HP + +A V+G  D+ 
Sbjct: 3   WLDSGDVGYFDSDGFLYIVDRKKELIKFKAEQVPPAMLEDVLLTHPGISDAAVIGRPDDM 182

Query: 548 MGE-EICACIRLKSGETTTAEEIKAFCKGKI-SHFKIPRYIVFVEGYPLTISGKIQKFKL 605
            GE  +   ++  S    T +E+K F    + S+ ++   + F +  P + SGKI +  L
Sbjct: 183 AGELPMAFVVKATSHADLTEKEVKDFVAKNVPSYMQLRGGVQFKKEIPKSPSGKILRRLL 362

Query: 606 REQMEQHL 613
           R++++  L
Sbjct: 363 RDELKTQL 386
>02291
          Length = 3161

 Score = 65.9 bits (159), Expect = 4e-11,   Method: Compositional matrix adjust.
 Identities = 94/349 (26%), Positives = 142/349 (40%), Gaps = 58/349 (16%)
 Frame = -1

Query: 262  FTSGTTGNPKGATLSHHNI-----VNNSMLIGQRLKMPTKTAEELRLVLPSPLYHCLGSV 316
            +TSGTTG PKG  LSH NI     VN S  + Q   + TK  ++  +    PL H    +
Sbjct: 2843 YTSGTTGTPKGVMLSHDNITYTVAVNMSSTMQQ---LNTKFGQQSGISY-LPLSHIAAQM 2676

Query: 317  GGTMVSMMHGATLLLSSPSFNGKKALEAISRE-KGTLLYGTPTMFVDILNQPDFSSYDFT 375
                V +  G T   + P    K +L A  RE +  +  G P ++  +      ++   T
Sbjct: 2675 MDIYVXIGFGGTTYFAQPDAL-KGSLGATLREVRPHIFLGVPRVWEKMQETMQTAARSVT 2499

Query: 376  SIRGGVIAGS-----------------PAPPELIRAIINK-------------------- 398
             ++  + A +                 PA   L  A++ K                    
Sbjct: 2498 GMKKKIGAWAKGVGLKANYAIMEGRSPPAXXPLANALVFKKVRGLLGLDRCLMQLSGAAP 2319

Query: 399  ---------MNMK-ELVVVYGTTENSPVTFMNFPEDTLEQKAGSVGRIMPHTEAQIVNVE 448
                     M++   +  VYG +E S    + FP+     +  SVGR +        N  
Sbjct: 2318 IAKETLEYFMSLNVPICEVYGMSECSGPHTVGFPK---VNRVNSVGREL--------NGC 2172

Query: 449  TGELTNLNVPG--ELYIRGYCVMQGYWGEPQKTFETVGQDKWYRTGDIALMDEQGFCKIV 506
            T EL N +  G  E+ + G  V  GY  + +KT E +       +GD+   D+ GF  I 
Sbjct: 2171 TTELANQDEDGNGEVVMHGRHVFMGYLNDEEKTKEALDDAGGLHSGDVGKKDKDGFLFIT 1992

Query: 507  GRSKDMIIR-GGENIYPAELEDFFLKHPQVQEAQVVG--VKDERMGEEI 552
            GR K++II  GGENI P  +ED      +V+EA  VG  V  +R  E++
Sbjct: 1991 GRIKELIITAGGENIPPVAIED------RVKEALPVGQPVHADRGQEKV 1863
>37217
          Length = 548

 Score = 61.2 bits (147), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 47/185 (25%), Positives = 83/185 (44%)
 Frame = -2

Query: 308 PLYHCLGSVGGTMVSMMHGATLLLSSPSFNGKKALEAISREKGTLLYGTPTMFVDILNQP 367
           P +H  G +  T++      T L+  P F  K  L AI + +  +    P + V +   P
Sbjct: 538 PWFHAFGCL--TLIKTATLGTRLVYLPKFEEKLFLSAIEKYRVMVALMVPPLMVFLAKHP 365

Query: 368 DFSSYDFTSIRGGVIAGSPAPPELIRAIINKMNMKELVVVYGTTENSPVTFMNFPEDTLE 427
               YD +S+   +   +P   E    I  ++ +  +   YG +E++    +   E    
Sbjct: 364 IVDKYDLSSLLVLLCGAAPLSRETEDQIKERLGIPFIRQGYGLSESTLSVLVQNDEHC-- 191

Query: 428 QKAGSVGRIMPHTEAQIVNVETGELTNLNVPGELYIRGYCVMQGYWGEPQKTFETVGQDK 487
            K GSV  +     A++++ +TG+    N  GEL  +G  +M+GY G+ + T  T+ +D 
Sbjct: 190 -KPGSVXVLNVGVYAKVIDPDTGKHLGANERGELCFKGPGIMKGYIGDKRSTQTTI-KDG 17

Query: 488 WYRTG 492
           W  TG
Sbjct: 16  WLHTG 2
>14264
          Length = 1790

 Score = 49.7 bits (117), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 78/362 (21%), Positives = 131/362 (36%), Gaps = 43/362 (11%)
 Frame = -3

Query: 262  FTSGTTGNPKGATLSHHNIVNNSMLIGQRLKMPTKTAEELRLVLPS------PLYHCLGS 315
            +TSGTTG PK    +            ++LKM T TA+ L +          PLYH    
Sbjct: 1020 YTSGTTGLPKPVYYNQ-----------KKLKMFTTTAQLLDVTTQDIVYTVLPLYHISAF 874

Query: 316  VGGTMVSMMHGATLLLSSPSFNGKKALEAISREKGTLLYGTPTMFVDILNQPDFSSYDFT 375
              G M  +  G T +L    F+  +          T++     +F  +L QP        
Sbjct: 873  GVGFMGLLHQGGTSVLKR-KFSASQFWSDCRTYNVTIVQYIGELFRYLLAQPKSELDGVH 697

Query: 376  SIRGGVIAGSPAPPELIRAIINKMNMKELVVVYGTTENSPVTFMNFPEDTLEQKAGSVGR 435
             +RG +  G+    ++   ++ +  + ++   Y  TE     F  F       K G++GR
Sbjct: 696  KVRGAI--GNGLRKDIFEEVLTRFKIIQVCEFYAATEGVSGLFNMF------NKPGAIGR 541

Query: 436  IMP------------------------HTEAQIVNVETGE--LTNLNVPGELYIRGYCVM 469
            + P                            + V V+ GE  L    VP ++  +G   +
Sbjct: 540  VSPFLNFLAPYPSVVVKFDYSTAMPVRDKNGRCVKVKPGEIGLFMSQVPDDIQTQGNLTV 361

Query: 470  QGYWGEP--QKTFETVGQ--DKWYRTGDIALMDEQGFCKIVGRSKDMIIRGGENIYPAEL 525
                 E   +K      +  D ++  GD+  +D+  F     R  D     GEN+   E+
Sbjct: 360  YKASKEANEKKLVRNAFKEGDLYFNYGDVFYLDKDYFVYFHDRIGDTFRWKGENVSTTEV 181

Query: 526  EDFFLKHPQVQEAQVVGV----KDERMGEEICACIRLKSGETTTAEEIK---AFCKGKIS 578
             +       + +A V GV     D R G    A + L  G T   E++K     C+ ++ 
Sbjct: 180  SNVLSTPDFISDANVYGVTVPGHDGRAG---MAALTLNEGTTLAPEQLKZMYTLCQSELP 10

Query: 579  HF 580
             +
Sbjct: 9    SY 4
>34113
          Length = 694

 Score = 46.6 bits (109), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 46/194 (23%), Positives = 80/194 (41%), Gaps = 15/194 (7%)
 Frame = -3

Query: 114 SGLLSIGLRKGD--RLGMWGPNSYAWVLIQLATAQAGIILVSVNPAYQSSELEYVLRKVG 171
           SGL ++G++ G     G++  NS  WV+   A     ++ V++        ++YV+    
Sbjct: 554 SGLFALGVKPGQDTNFGIFTQNSSEWVIADQACQMYSMVTVALYDTLGVEAVKYVVNLAE 375

Query: 172 CKGIVFPKQFKTQQYYD------------ILKQVCPELE-KAQPGALKSERLPDLTTVIS 218
              +V  K+ + +   +            + +++  EL+ KAQ   +K  R  ++     
Sbjct: 374 IGTVVCDKEVRAKILLEGKSELPCLKLIVMXEEITEELQQKAQRAGVKIIRFSEV----- 210

Query: 219 VDAPLPGTLLLDDIVAAGGKEQNLAQLRYNQRFLSCYDPINIQFTSGTTGNPKGATLSHH 278
                      +D+     +E  L +           D   I FTSGTTGNPKG  L+H 
Sbjct: 209 -----------EDLGKKNIREPLLPKPS---------DVCTICFTSGTTGNPKGVVLTHA 90

Query: 279 NIVNNSMLIGQRLK 292
           N+V N   +   LK
Sbjct: 89  NLVANVSSVKVSLK 48
>19187
          Length = 742

 Score = 43.5 bits (101), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 21/60 (35%), Positives = 28/60 (46%)
 Frame = +2

Query: 486 DKWYRTGDIALMDEQGFCKIVGRSKDMIIRGGENIYPAELEDFFLKHPQVQEAQVVGVKD 545
           D W+RT D+   ++      +GR  D I RG    YP  LE      P V++  VV V D
Sbjct: 530 DGWFRTDDMGCFNQDKHIIHLGRRTDAITRGAYLCYPGWLETLLRHSPSVRDVCVVPVAD 709
>25970
          Length = 418

 Score = 41.2 bits (95), Expect = 0.001,   Method: Composition-based stats.
 Identities = 31/100 (31%), Positives = 43/100 (43%), Gaps = 3/100 (3%)
 Frame = -3

Query: 511 DMIIRGGENIYPAELEDFFLKHPQVQEAQVVGVKDERMGEEICACIRLKSGE---TTTAE 567
           DM+   G  +  AE+E     HP+V E+ VV       GE +   I     E        
Sbjct: 413 DMLNVSGHLMSTAEVESVLTAHPRVAESAVVSRPHPVKGECLYCFITPNENEPFDQAMVS 234

Query: 568 EIKAFCKGKISHFKIPRYIVFVEGYPLTISGKIQKFKLRE 607
           E+K   + +I  F +P  I    G P T SGKI +  LR+
Sbjct: 233 ELKKMVRERIGPFAMPDVIQNAPGLPKTRSGKIMRRVLRK 114
>03756
          Length = 992

 Score = 38.5 bits (88), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 43/193 (22%), Positives = 78/193 (40%), Gaps = 11/193 (5%)
 Frame = +2

Query: 100 LNFAQLKEEVDKAASGLLSIGLRKGDR--LGMWGPNSYAWVLIQLATAQAGIILVSVNPA 157
           +++ Q+ +      SGL+S G++  +   +G++  N   W L  L      ++ V +   
Sbjct: 284 MSYRQVLDRAHCFGSGLISKGVQPSNSSFVGIYSGNCVEWSLADLGCHMYSMVPVPLYDT 463

Query: 158 YQSSELEYVLRKVGCKGIVFPKQFKTQQYYDILKQVCPELEK-AQPGALKSERLPDLTTV 216
                  Y++ +     +V     K ++  +I  QV P L++    G    + + DL   
Sbjct: 464 LGPQACVYIINQTKLCTVVCDDVNKAKRLLEIADQV-PSLKRFIFTGKTWPQDIRDLANE 640

Query: 217 ISVDAPLPGTLLLDDIVAAGGKEQNLAQLRYNQRFLSCYDPI--------NIQFTSGTTG 268
             V+      L   +I + G K+                DPI         + +TSGTTG
Sbjct: 641 RKVE-----LLTFKEIESIGTKDTR--------------DPIPPKPDDLATLCYTSGTTG 763

Query: 269 NPKGATLSHHNIV 281
           +PKG  L+H N +
Sbjct: 764 DPKGVMLTHANFL 802
>36553
          Length = 389

 Score = 33.5 bits (75), Expect = 0.25,   Method: Composition-based stats.
 Identities = 25/88 (28%), Positives = 37/88 (42%), Gaps = 7/88 (7%)
 Frame = +1

Query: 535 VQEAQVVGVKDERMGEEICAC-------IRLKSGETTTAEEIKAFCKGKISHFKIPRYIV 587
           +Q+  VVGV D  MG+E+CAC       I       T    I       +S    PR+ +
Sbjct: 7   LQDVMVVGVPDPAMGQELCACFVAHDPLINEDHVRQTVESTILTDVNDPLS--PRPRHYL 180

Query: 588 FVEGYPLTISGKIQKFKLREQMEQHLKL 615
               +P T + K  + +LR    + L L
Sbjct: 181 AFHDFPKTYTDKPARKQLRRHAAERLTL 264
>22123
          Length = 347

 Score = 31.2 bits (69), Expect = 1.3,   Method: Composition-based stats.
 Identities = 12/25 (48%), Positives = 17/25 (68%)
 Frame = +1

Query: 459 GELYIRGYCVMQGYWGEPQKTFETV 483
           G+LY RG  +M+GY   PQ T +T+
Sbjct: 199 GDLYKRGXLIMRGYHKNPQATADTI 273
>16054
          Length = 739

 Score = 30.0 bits (66), Expect = 2.6,   Method: Compositional matrix adjust.
 Identities = 11/23 (47%), Positives = 15/23 (65%)
 Frame = -2

Query: 250 RFLSCYDPINIQFTSGTTGNPKG 272
           R L+C+DPIN+ FTS +   P  
Sbjct: 90  RCLACFDPINLVFTSSSCDPPTS 22
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31542612|ref|NP_598826.2| ependymin 2 [Mus musculus]
         (224 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

28644                                                                 117   3e-27
12791                                                                  35   0.028
12352                                                                  33   0.081
31785                                                                  28   3.6  
21607                                                                  28   4.2  
>28644
          Length = 568

 Score =  117 bits (294), Expect = 3e-27,   Method: Compositional matrix adjust.
 Identities = 53/129 (41%), Positives = 79/129 (61%), Gaps = 3/129 (2%)
 Frame = +2

Query: 89  KRLFEYILLYKEGVMFQIEQATKQCAKIPLVESWDPLDIPQNSTFEDQYSIGGPQEQILV 148
           ++  E+I L KE VM++I  + K C KIP+   W    +P N+TFE +Y +GGP E++  
Sbjct: 2   RQFREFITLAKENVMYEINMSLKTCTKIPMRRPWRAYGVPSNATFEAEYYMGGPGEELWA 181

Query: 149 QEWSDRRTARSYETWIGVYTAKDCYPVQETFIRNYTVV---MSTRFFDVQLSIKDPSVFT 205
            EWSDR   R  E W+GV++ K C+P++E  I +Y  V   ++T F+D+   I  PSVF 
Sbjct: 182 HEWSDRIPYRQREFWVGVFSLKSCFPIREVLIADYQQVNSTITTNFYDIVEGIPKPSVFI 361

Query: 206 PPSTCQAAQ 214
           PP+ C+ A 
Sbjct: 362 PPTYCEKAN 388
>12791
          Length = 835

 Score = 34.7 bits (78), Expect = 0.028,   Method: Compositional matrix adjust.
 Identities = 29/101 (28%), Positives = 44/101 (43%), Gaps = 8/101 (7%)
 Frame = +1

Query: 122 WDPLD---IPQNSTFEDQYSIGGPQEQILVQEWSDRRTARSYETWIGVYTAKDCYPVQET 178
            DPL    IP+ +      S+G  +E + V  ++   T   Y  +    T K C PV   
Sbjct: 100 LDPLKRHCIPEGAVKLGTGSLG--KENVTVSTFAYTLTDYPY-LFQSTVTQKGCLPVHVV 270

Query: 179 FIRNYT-----VVMSTRFFDVQLSIKDPSVFTPPSTCQAAQ 214
           ++   +      V S    DV   IKDPS+F  P  C++A+
Sbjct: 271 YLVKSSEAGSGAVYSLEVMDVTPGIKDPSIFDIPPQCKSAK 393
>12352
          Length = 964

 Score = 33.1 bits (74), Expect = 0.081,   Method: Compositional matrix adjust.
 Identities = 16/35 (45%), Positives = 22/35 (62%)
 Frame = +3

Query: 180 IRNYTVVMSTRFFDVQLSIKDPSVFTPPSTCQAAQ 214
           +  YTV   + + +V + I DPSVFTPP +C  AQ
Sbjct: 582 VPTYTV---SSYTNVTVGISDPSVFTPPVSCIKAQ 677
>31785
          Length = 417

 Score = 27.7 bits (60), Expect = 3.6,   Method: Compositional matrix adjust.
 Identities = 9/40 (22%), Positives = 20/40 (50%)
 Frame = +1

Query: 88  CKRLFEYILLYKEGVMFQIEQATKQCAKIPLVESWDPLDI 127
           C R+F   L+    ++  +   + +C ++ ++    PLDI
Sbjct: 124 CTRVFNTTLIVTRQILINVSSMS*KCQQVQMIRIGSPLDI 243
>21607
          Length = 723

 Score = 27.7 bits (60), Expect = 4.2,   Method: Compositional matrix adjust.
 Identities = 16/46 (34%), Positives = 22/46 (47%), Gaps = 1/46 (2%)
 Frame = +1

Query: 8   RLVQGPRGTWLLGSLWVWVLCGLGMA-GSLGTPQPCQAPQQWEGRQ 52
           RLV+ P  +WL  +      C + +   SLG  QPC    +W  RQ
Sbjct: 136 RLVETPCMSWLCSNK-----CNVSLNYSSLGHSQPCNVNTEWPRRQ 258
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31980922|ref|NP_061266.2| eukaryotic translation
elongation factor 1 beta 2 [Mus musculus]
         (225 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

00432                                                                 117   3e-27
17387                                                                  36   0.013
10621                                                                  29   1.2  
27365                                                                  29   1.4  
23211                                                                  29   1.6  
03891                                                                  29   2.0  
>00432
          Length = 1557

 Score =  117 bits (293), Expect = 3e-27,   Method: Compositional matrix adjust.
 Identities = 54/84 (64%), Positives = 68/84 (80%)
 Frame = -1

Query: 142  ILLDVKPWDDETDMTKLEECVRSIQADGLVWGSSKLVPVGYGIKKLQIQCVVEDDKVGTD 201
            ++LD KPWDDETDM ++E  VRSIQ DGL WG++KL  + YGIKKL I CVVED+K+  +
Sbjct: 1182 VVLDCKPWDDETDMKEMERLVRSIQKDGLNWGAAKLQELAYGIKKLVIICVVEDEKISVE 1003

Query: 202  MLEEQITAFEDYVQSMDVAAFNKI 225
             L+E+I  FEDYVQS+D+AAFNKI
Sbjct: 1002 DLKEEIEEFEDYVQSVDIAAFNKI 931
>17387
          Length = 493

 Score = 35.8 bits (81), Expect = 0.013,   Method: Compositional matrix adjust.
 Identities = 20/68 (29%), Positives = 34/68 (50%), Gaps = 7/68 (10%)
 Frame = +1

Query: 12  LQVLNDYLADKSYIEGYVPSQADVA-------VFEAVSGPPPADLCHALRWYNHIKSYEK 64
           LQ LN YL+DK Y   + P+ AD+        VF  ++        H  RW+++I+  ++
Sbjct: 196 LQELNSYLSDKVYFVTHHPTVADIVIYHGLFNVFTKLAYSEKEKYIHLSRWFDNIQQDQR 375

Query: 65  EKASLPGV 72
            + SL  +
Sbjct: 376 IRQSLQRL 399
>10621
          Length = 1304

 Score = 29.3 bits (64), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 12/27 (44%), Positives = 19/27 (70%)
 Frame = +2

Query: 11  GLQVLNDYLADKSYIEGYVPSQADVAV 37
            L VLNDYL  ++Y+ G   +QAD+++
Sbjct: 416 ALTVLNDYLLTRTYLVGESVTQADISL 496
>27365
          Length = 860

 Score = 29.3 bits (64), Expect = 1.4,   Method: Compositional matrix adjust.
 Identities = 13/31 (41%), Positives = 18/31 (58%)
 Frame = +1

Query: 12  LQVLNDYLADKSYIEGYVPSQADVAVFEAVS 42
           L  L+DYL  K +I G  P + D A+F  +S
Sbjct: 559 LTALSDYLGTKKFIMGDRPCEVDCAIFGQLS 651
>23211
          Length = 1156

 Score = 28.9 bits (63), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 12/26 (46%), Positives = 19/26 (73%)
 Frame = +1

Query: 12 LQVLNDYLADKSYIEGYVPSQADVAV 37
          L VLNDYL  ++Y+ G   +QAD+++
Sbjct: 1  LTVLNDYLLTRTYLVGESVTQADISL 78
>03891
          Length = 1119

 Score = 28.9 bits (63), Expect = 2.0,   Method: Compositional matrix adjust.
 Identities = 10/16 (62%), Positives = 13/16 (81%)
 Frame = +3

Query: 142 ILLDVKPWDDETDMTK 157
           ++LD KPWDDETD  +
Sbjct: 135 VVLDCKPWDDETDRDR 182
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|36031035|ref|NP_031816.2| chondroitin sulfate
proteoglycan 6 [Mus musculus]
         (1217 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

28181                                                                 120   3e-27
15478                                                                  66   7e-11
09495                                                                  58   2e-08
35107                                                                  56   7e-08
20290                                                                  37   0.037
>28181
          Length = 604

 Score =  120 bits (302), Expect = 3e-27,   Method: Compositional matrix adjust.
 Identities = 62/138 (44%), Positives = 97/138 (70%)
 Frame = -1

Query: 179 MKETEGKREKINELLKYIXXXXXXXXXXXXXXAQYQKWDKMRRALEYTIYNQELNETRAK 238
           ++ETEGKREKIN+LLKYI               +YQKWDKMRR+LEYTI++ EL +TR K
Sbjct: 583 LRETEGKREKINDLLKYIEERLNTLESEKEELKEYQKWDKMRRSLEYTIHDHELKDTRRK 404

Query: 239 LDELSAKRETSGEKSRQLRDAQQDARDKMEDIERQVRELKTKISAMKEEKEQLSAERQEQ 298
           LDEL A+R++SG+ ++ +RD Q  A D ++ + ++++ELK +  ++ EE++ L +E  + 
Sbjct: 403 LDELQARRDSSGQMTKDMRDDQLKAADLVKTLNKELKELKQQFHSLTEERDSLGSESHDL 224

Query: 299 IKQRTKLELKAKDLQDEL 316
            K++ +LEL  KD++DE+
Sbjct: 223 TKKKAQLELDIKDVEDEM 170
>15478
          Length = 1282

 Score = 66.2 bits (160), Expect = 7e-11,   Method: Compositional matrix adjust.
 Identities = 53/228 (23%), Positives = 117/228 (51%), Gaps = 7/228 (3%)
 Frame = +1

Query: 73  VISAFVEIIFDNSDNR-LPIDKEE----VSLRRVIGAKKDQYFLDKKMVTKNDVMNLLES 127
           V  A V I FDN D +  P+  E+    V  R+V+   +++Y ++      N V +L  S
Sbjct: 67  VTKATVSITFDNQDKKQSPLGYEQYDEIVVTRQVVIGGRNKYLINGSNANNNRVQDLFRS 246

Query: 128 AGFSRSNPYYIVKQGKINQMATAPDSQRLKLLREVAGTRVYDERKEESISLMKETEGKRE 187
              + +NP++++ QG+I ++      + L ++ E AGTR+Y+ ++E +   +++ + K  
Sbjct: 247 VQLNVNNPHFLIMQGRITKVLNMKPPEILSMIEEAAGTRLYETKREAAQRTIEKKDAKLR 426

Query: 188 KINELLKYIXXXXXXXXXXXXXXAQYQKWDKMRRALEYTIYNQELNETRAKLDELSA--K 245
           +I+ +LK                + Y ++ K+ R LE+      L++       + A  K
Sbjct: 427 EIDTVLK--EDITPTLTKLRDERSSYLEYQKILRELEH------LSKLYVAYQFVCAEEK 582

Query: 246 RETSGEKSRQLRDAQQDARDKMEDIERQVRELKTKISAMKEEKEQLSA 293
           ++ S E+  ++++  +  +++ME+I+ ++ EL  KI+ +  ++++ S 
Sbjct: 583 KKRSAEELVEMQEVIKATQERMEEIKGKIGELDEKIAELTRQRDEESG 726
>09495
          Length = 1177

 Score = 58.2 bits (139), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 44/182 (24%), Positives = 78/182 (42%), Gaps = 17/182 (9%)
 Frame = -3

Query: 1    MYIKQVIIQGFRSYRDQTIVDPFSSKHNVIVGRNGSGKSNFFYAIQFVLSDEFSHLRPEQ 60
            + I  ++ + F+SY     + PF      IVG NGSGKSN   ++ FV     + +R ++
Sbjct: 1025 LMITHIVNENFKSYAGVQTLGPFHKSFTSIVGPNGSGKSNVIDSMLFVFGYRANKIRSKK 846

Query: 61   RLALLHEG-----TGPRVISAFVEIIFDNSDNR-----LPIDKEEVSLRRVIGAKKDQYF 110
               L+H        G   ++   + I D          +P D + V  R         Y 
Sbjct: 845  VSVLIHNSENHRDMGSCCVAVHFQKIVDTGPGEDEYTVVP-DSKIVVARTAFKDNTSSYS 669

Query: 111  LDKKMVTKNDVMNLLESAGFSRSNPYYIVKQGKINQMATA-PDSQR------LKLLREVA 163
            ++ K  T  +V  LL  +G    +  +++ QG++ Q+A   P +Q       L+ L ++ 
Sbjct: 668  VNGKRATYKEVAALLRGSGIDLDHNRFLILQGEVEQIAMMKPKAQSEHEDGMLEFLEDII 489

Query: 164  GT 165
            G+
Sbjct: 488  GS 483
>35107
          Length = 679

 Score = 56.2 bits (134), Expect = 7e-08,   Method: Composition-based stats.
 Identities = 49/176 (27%), Positives = 78/176 (44%), Gaps = 7/176 (3%)
 Frame = +2

Query: 995  EQKEKLIKRQEELDRGYKSIMELMNVL-----ELRK--YEAIQLTFKQVSKNFSEVFQKL 1047
            E++E  + R  ELD+    I E+ +       ELRK   +     F  ++    E++Q +
Sbjct: 107  EKEELYLSRVAELDQ----ITEVRDKQRKYHEELRKQRLDEFMTGFAVITGKLKEMYQMI 274

Query: 1048 VPGGKATLVMKKGDVXXXXXXXXXXXXXXXXXXXXXXXXVPSVDQFTGVGIRVSFTGKQG 1107
              GG A L +                             V S+D F+  GI  S    + 
Sbjct: 275  TLGGDAELEL-----------------------------VDSLDPFSE-GIVFSVRPPKK 364

Query: 1108 EMREMQQLSGGQKSLVALALIFAIQKCDPAPFYLFDEIDQALDAQHRKAVSDMIME 1163
              + +  LSGG+K+L +LAL+FA+    P P Y+ DEID ALD ++   V++ I +
Sbjct: 365  SWKNISNLSGGEKTLSSLALVFALHHYKPTPLYVMDEIDAALDFKNVSIVANYIKD 532
>20290
          Length = 1550

 Score = 37.4 bits (85), Expect = 0.037,   Method: Compositional matrix adjust.
 Identities = 25/75 (33%), Positives = 35/75 (46%), Gaps = 9/75 (12%)
 Frame = +3

Query: 1110 REMQQLSGGQKSLVALALIFAIQKCDPAPFYLFDEIDQALDAQHRKAVSDMIMELAVHAQ 1169
            +E+Q LSGG+   VAL L        PA  YL DE    LD++ R   + +I    +HA+
Sbjct: 1032 QEVQNLSGGELQRVALVLCLG----KPADVYLIDEPSAYLDSEQRLVAAKVIKRYILHAK 1199

Query: 1170 ---------FITTTF 1175
                     FI  T+
Sbjct: 1200 KTGFVVEHDFIMATY 1244
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|20373163|ref|NP_598850.1| PDZ-domain protein scribble
[Mus musculus]
         (1665 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

34576                                                                 120   4e-27
09309                                                                  74   5e-13
20480                                                                  58   2e-09
19531                                                                  61   3e-09
05532                                                                  58   3e-08
20073                                                                  57   9e-08
03831                                                                  53   1e-06
30747                                                                  53   1e-06
29705                                                                  52   3e-06
01502                                                                  47   9e-05
02951                                                                  46   1e-04
27345                                                                  43   0.001
37214                                                                  40   0.006
39267                                                                  40   0.010
20775                                                                  39   0.018
38751                                                                  39   0.018
08480                                                                  39   0.020
08106                                                                  38   0.035
26154                                                                  37   0.055
37239                                                                  33   0.94 
17298                                                                  33   0.95 
14078                                                                  32   1.8  
15446                                                                  30   8.4  
17623                                                                  30   9.9  
>34576
          Length = 1496

 Score =  120 bits (301), Expect = 4e-27,   Method: Compositional matrix adjust.
 Identities = 101/332 (30%), Positives = 141/332 (42%), Gaps = 25/332 (7%)
 Frame = +2

Query: 68  DNEIQRLPPEVANFMQLVELDVSRNDIPEIPESIKFCKALEIADFSGNPLSRLPDGFTQL 127
           +N +  LP ++A   +L E+    N +  IPESI +C  LEI     N L RLP  F  L
Sbjct: 5   NNCLTVLPEDIAELFELKEVYCGSNQLTLIPESICWCSNLEILSLHKNHLERLPVEFANL 184

Query: 128 RSLAHLALND-----------------------VSLQALPGDVGNLANLVTLELRENLLK 164
           R +  L L+D                        SL  +P ++G L  L  L L  N  K
Sbjct: 185 RKITRLILSDNNFTSVPVAIGSLTELEALLLDGNSLHEIPQELGTLKKLTHLSLGRNAFK 364

Query: 165 SLPASLSFLVKLEQLDLGGNDLEVLPDTLGALPNLRELWLDRNQLSALPPELGNLRRLVC 224
             P     +  LE LDL  N +  +P  +  L +LREL++ +N +S    EL  L++L  
Sbjct: 365 EFPRPACSITSLEILDLSDNKITEIPSDIAQLLSLRELYMKKNAVSVFCAELCALQKLQM 544

Query: 225 LDVSENRLEELPVEXXXXXXXXXXXXXXXXXXXXPEGIGQLKQLSILKVDQNRLCEVTEA 284
            D S N L +LP E                    P+    +  L  L   Q    +V   
Sbjct: 545 ADFSNNGLLDLPEEVSVLGCLQELDLSNNQFFEFPKTACSIPHLHKLVFSQQEGLKVPSL 724

Query: 285 IGDCE--NLSELILTENLLTALPHSLGKLTKLTNLNVDRNHLEVLPPEIGGCVALSVLSL 342
             + E  +++EL+L+ N L  LP ++  +  L  L  D N + VLP  +    AL VL L
Sbjct: 725 PDEIEFSSVAELVLSHNTLRTLPRTISAMKNLVVLKADHNEICVLPDALCDMTALQVLHL 904

Query: 343 RDNRLAVLPPELAHTAELHVLDVAGNRLRSLP 374
            DN L  LP E      L  L +  N LRS P
Sbjct: 905 NDNLLPTLPLEFDQLKGLQDLCLHNNPLRSPP 1000

 Score = 59.7 bits (143), Expect = 9e-09,   Method: Compositional matrix adjust.
 Identities = 40/133 (30%), Positives = 69/133 (51%), Gaps = 1/133 (0%)
 Frame = +2

Query: 259 PEGIGQLKQLSILKVDQNRLCEVTEAIGDCENLSELILTENLLTALPHSLGKLTKLTNLN 318
           PE I     L IL + +N L  +     +   ++ LIL++N  T++P ++G LT+L  L 
Sbjct: 95  PESICWCSNLEILSLHKNHLERLPVEFANLRKITRLILSDNNFTSVPVAIGSLTELEALL 274

Query: 319 VDRNHLEVLPPEIGGCVALSVLSLRDNRLAVLPPELAHTAELHVLDVAGNRLRSLPFALT 378
           +D N L  +P E+G    L+ LSL  N     P        L +LD++ N++  +P  + 
Sbjct: 275 LDGNSLHEIPQELGTLKKLTHLSLGRNAFKEFPRPACSITSLEILDLSDNKITEIPSDIA 454

Query: 379 H-LNLKALWLAEN 390
             L+L+ L++ +N
Sbjct: 455 QLLSLRELYMKKN 493
>09309
          Length = 1508

 Score = 73.9 bits (180), Expect = 5e-13,   Method: Compositional matrix adjust.
 Identities = 69/246 (28%), Positives = 118/246 (47%), Gaps = 3/246 (1%)
 Frame = +3

Query: 150 LANLVTLELRENLLKSLPASLSFLVKLEQLDLGGNDLEVLPDTLGALPNLRELWLDRNQL 209
           L+ L  L++R+N L  LP  ++ L  LE+LDL  ND+ +LP +LG + +L+ + LD N +
Sbjct: 15  LSTLNFLDVRDNKLAKLPDEITLLENLERLDLSNNDISMLPYSLGTINSLKSVILDGNPM 194

Query: 210 SALPPELGNLRRLVCLDVSENRLEELPVEXXXXXXXXXXXXXXXXXXXXPEGIGQLKQLS 269
            ++  ++     +       +R+EE                           + Q K + 
Sbjct: 195 KSIRRDIIMRGTMELKKYLRSRIEEPESRPAPVTSKESVLPTGSGDTQQAHEMQQFKTMD 374

Query: 270 ILKVDQNRL-CEVTEAIGDCENLSELILTENLLTALPHSLGKLTK-LTNLNVDRNHLEVL 327
               + N +  ++ E   +   ++ + +++N  T LP +L  L   LT LN+  N L  L
Sbjct: 375 FSGKNANAVPADMWEKAQEAA-VTSVNISKNQFTQLPSNLFLLVNSLTELNMGFNKLTGL 551

Query: 328 PPEIGGCVALSVLSLRDNRLAVLPPELAHTAELHVLDVAGNRLRSLPFALTHL-NLKALW 386
            P+IG  + L+ L LR+N L+ LP EL     L  + ++ NR   +P AL  L  L+ L+
Sbjct: 552 SPDIGLFLKLTCLDLRNNGLSSLPAELCSMQALREVILSCNRFTEIPQALYELKKLEILF 731

Query: 387 LAENQA 392
           L +NQ 
Sbjct: 732 LNDNQV 749

 Score = 72.8 bits (177), Expect = 1e-12,   Method: Compositional matrix adjust.
 Identities = 76/310 (24%), Positives = 135/310 (43%), Gaps = 25/310 (8%)
 Frame = +3

Query: 61  LRKLGLSDNEIQRLPPEVANFMQLVELDVSRNDIPEIPESIKFCKALEIADFSGNPLSR- 119
           L  L + DN++ +LP E+     L  LD+S NDI  +P S+    +L+     GNP+   
Sbjct: 24  LNFLDVRDNKLAKLPDEITLLENLERLDLSNNDISMLPYSLGTINSLKSVILDGNPMKSI 203

Query: 120 ----LPDGFTQLRSLAHLALND-------VSLQ--ALPGDVGN------LANLVTLELRE 160
               +  G  +L+      + +       V+ +   LP   G+      +    T++   
Sbjct: 204 RRDIIMRGTMELKKYLRSRIEEPESRPAPVTSKESVLPTGSGDTQQAHEMQQFKTMDFSG 383

Query: 161 NLLKSLPASL---SFLVKLEQLDLGGNDLEVLPDTLGALPN-LRELWLDRNQLSALPPEL 216
               ++PA +   +    +  +++  N    LP  L  L N L EL +  N+L+ L P++
Sbjct: 384 KNANAVPADMWEKAQEAAVTSVNISKNQFTQLPSNLFLLVNSLTELNMGFNKLTGLSPDI 563

Query: 217 GNLRRLVCLDVSENRLEELPVEXXXXXXXXXXXXXXXXXXXXPEGIGQLKQLSILKVDQN 276
           G   +L CLD+  N L  LP E                       +  ++ L  + +  N
Sbjct: 564 GLFLKLTCLDLRNNGLSSLPAE-----------------------LCSMQALREVILSCN 674

Query: 277 RLCEVTEAIGDCENLSELILTENLLTAL-PHSLGKLTKLTNLNVDRNHLEVLPPEIGGCV 335
           R  E+ +A+ + + L  L L +N ++ + P  L +L  L  L++  N++  +PPE+G C 
Sbjct: 675 RFTEIPQALYELKKLEILFLNDNQVSTIEPSGLQRLGVLATLDLQNNNISQVPPELGNCT 854

Query: 336 ALSVLSLRDN 345
           +L  L L  N
Sbjct: 855 SLRSLQLGGN 884

 Score = 58.9 bits (141), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 46/149 (30%), Positives = 74/149 (49%), Gaps = 1/149 (0%)
 Frame = +3

Query: 14  VESVDKRHCSLQVVPEEIYRYSRSLEELLLDANQLRELPKPFFRLLNLRKLGLSDNEIQR 73
           V SV+        +P  ++    SL EL +  N+L  L       L L  L L +N +  
Sbjct: 438 VTSVNISKNQFTQLPSNLFLLVNSLTELNMGFNKLTGLSPDIGLFLKLTCLDLRNNGLSS 617

Query: 74  LPPEVANFMQLVELDVSRNDIPEIPESIKFCKALEIADFSGNPLSRL-PDGFTQLRSLAH 132
           LP E+ +   L E+ +S N   EIP+++   K LEI   + N +S + P G  +L  LA 
Sbjct: 618 LPAELCSMQALREVILSCNRFTEIPQALYELKKLEILFLNDNQVSTIEPSGLQRLGVLAT 797

Query: 133 LALNDVSLQALPGDVGNLANLVTLELREN 161
           L L + ++  +P ++GN  +L +L+L  N
Sbjct: 798 LDLQNNNISQVPPELGNCTSLRSLQLGGN 884
>20480
          Length = 638

 Score = 50.1 bits (118), Expect(2) = 2e-09,   Method: Compositional matrix adjust.
 Identities = 36/113 (31%), Positives = 58/113 (51%)
 Frame = -1

Query: 262 IGQLKQLSILKVDQNRLCEVTEAIGDCENLSELILTENLLTALPHSLGKLTKLTNLNVDR 321
           + +L +L IL +  N +  V+  +   + L +LIL  N + A+P S+G + +L  L V+ 
Sbjct: 446 VFRLPKLQILDLSNNDIEAVSSELSGLQTLRQLILNGNKMEAIPGSIGFMKELRVLGVNE 267

Query: 322 NHLEVLPPEIGGCVALSVLSLRDNRLAVLPPELAHTAELHVLDVAGNRLRSLP 374
           N L  +P  IG    L +L L  N L  L P +     L  L ++GN + +LP
Sbjct: 266 NRLREVPDSIGNLENLEILGLERNCLEFLNPVVCKLEGLLRLGLSGNHMTNLP 108

 Score = 32.0 bits (71), Expect(2) = 2e-09,   Method: Composition-based stats.
 Identities = 12/29 (41%), Positives = 21/29 (72%)
 Frame = -2

Query: 208 QLSALPPELGNLRRLVCLDVSENRLEELP 236
           QL+ +P  + +L +LVCL +S N++ E+P
Sbjct: 607 QLTQMPDPVFDLEQLVCLSLSNNKITEIP 521

 Score = 57.8 bits (138), Expect = 4e-08,   Method: Compositional matrix adjust.
 Identities = 47/150 (31%), Positives = 74/150 (49%)
 Frame = -1

Query: 163 LKSLPASLSFLVKLEQLDLGGNDLEVLPDTLGALPNLRELWLDRNQLSALPPELGNLRRL 222
           L+++  S+  L KL+ LDL  ND+E +   L  L  LR+L L+ N++ A+P  +G ++ L
Sbjct: 467 LQAVNRSVFRLPKLQILDLSNNDIEAVSSELSGLQTLRQLILNGNKMEAIPGSIGFMKEL 288

Query: 223 VCLDVSENRLEELPVEXXXXXXXXXXXXXXXXXXXXPEGIGQLKQLSILKVDQNRLCEVT 282
             L V+ENRL E+                       P+ IG L+ L IL +++N L  + 
Sbjct: 287 RVLGVNENRLREV-----------------------PDSIGNLENLEILGLERNCLEFLN 177

Query: 283 EAIGDCENLSELILTENLLTALPHSLGKLT 312
             +   E L  L L+ N +T LP  +  L 
Sbjct: 176 PVVCKLEGLLRLGLSGNHMTNLPREVENLI 87

 Score = 50.8 bits (120), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 44/144 (30%), Positives = 68/144 (47%)
 Frame = -1

Query: 47  QLRELPKPFFRLLNLRKLGLSDNEIQRLPPEVANFMQLVELDVSRNDIPEIPESIKFCKA 106
           QL+ + +  FRL  L+ L LS+N+I+ +  E++    L +L ++ N +  IP SI F K 
Sbjct: 470 QLQAVNRSVFRLPKLQILDLSNNDIEAVSSELSGLQTLRQLILNGNKMEAIPGSIGFMKE 291

Query: 107 LEIADFSGNPLSRLPDGFTQLRSLAHLALNDVSLQALPGDVGNLANLVTLELRENLLKSL 166
           L +                       L +N+  L+ +P  +GNL NL  L L  N L+ L
Sbjct: 290 LRV-----------------------LGVNENRLREVPDSIGNLENLEILGLERNCLEFL 180

Query: 167 PASLSFLVKLEQLDLGGNDLEVLP 190
              +  L  L +L L GN +  LP
Sbjct: 179 NPVVCKLEGLLRLGLSGNHMTNLP 108

 Score = 50.4 bits (119), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 42/148 (28%), Positives = 66/148 (44%)
 Frame = -1

Query: 91  RNDIPEIPESIKFCKALEIADFSGNPLSRLPDGFTQLRSLAHLALNDVSLQALPGDVGNL 150
           R  +  +  S+     L+I D S N +  +    + L++L  L LN   ++A+PG +G  
Sbjct: 476 RQQLQAVNRSVFRLPKLQILDLSNNDIEAVSSELSGLQTLRQLILNGNKMEAIPGSIG-- 303

Query: 151 ANLVTLELRENLLKSLPASLSFLVKLEQLDLGGNDLEVLPDTLGALPNLRELWLDRNQLS 210
                                F+ +L  L +  N L  +PD++G L NL  L L+RN L 
Sbjct: 302 ---------------------FMKELRVLGVNENRLREVPDSIGNLENLEILGLERNCLE 186

Query: 211 ALPPELGNLRRLVCLDVSENRLEELPVE 238
            L P +  L  L+ L +S N +  LP E
Sbjct: 185 FLNPVVCKLEGLLRLGLSGNHMTNLPRE 102

 Score = 43.1 bits (100), Expect(2) = 6e-05,   Method: Compositional matrix adjust.
 Identities = 38/127 (29%), Positives = 61/127 (48%)
 Frame = -1

Query: 24  LQVVPEEIYRYSRSLEELLLDANQLRELPKPFFRLLNLRKLGLSDNEIQRLPPEVANFMQ 83
           LQ V   ++R  + L+ L L  N +  +      L  LR+L L+ N+++ +P  +    +
Sbjct: 467 LQAVNRSVFRLPK-LQILDLSNNDIEAVSSELSGLQTLRQLILNGNKMEAIPGSIGFMKE 291

Query: 84  LVELDVSRNDIPEIPESIKFCKALEIADFSGNPLSRLPDGFTQLRSLAHLALNDVSLQAL 143
           L  L V+ N + E+P+SI   + LEI     N L  L     +L  L  L L+   +  L
Sbjct: 290 LRVLGVNENRLREVPDSIGNLENLEILGLERNCLEFLNPVVCKLEGLLRLGLSGNHMTNL 111

Query: 144 PGDVGNL 150
           P +V NL
Sbjct: 110 PREVENL 90

 Score = 23.1 bits (48), Expect(2) = 6e-05,   Method: Compositional matrix adjust.
 Identities = 12/27 (44%), Positives = 17/27 (62%)
 Frame = -2

Query: 176 LEQLDLGGNDLEVLPDTLGALPNLREL 202
           LEQL L  N+ + +P  +  L +LREL
Sbjct: 82  LEQLLLDDNEFDFVPVQVYWLEDLREL 2

 Score = 37.7 bits (86), Expect = 0.041,   Method: Composition-based stats.
 Identities = 19/50 (38%), Positives = 29/50 (58%)
 Frame = -2

Query: 66  LSDNEIQRLPPEVANFMQLVELDVSRNDIPEIPESIKFCKALEIADFSGN 115
           + D ++ ++P  V +  QLV L +S N I EIP++I     LE+   SGN
Sbjct: 619 MGDLQLTQMPDPVFDLEQLVCLSLSNNKITEIPDAISHLDNLEVLVLSGN 470
>19531
          Length = 415

 Score = 61.2 bits (147), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 36/107 (33%), Positives = 62/107 (57%)
 Frame = -2

Query: 260 EGIGQLKQLSILKVDQNRLCEVTEAIGDCENLSELILTENLLTALPHSLGKLTKLTNLNV 319
           EG+ QL  L++L V  N L  +  A+G+ ENL +L ++ N L  LP  +G+L+ L +++ 
Sbjct: 321 EGLAQLPALTVLDVHDNHLQSLPNALGELENLQKLNISHNQLVELPSCIGRLSNLVSVHA 142

Query: 320 DRNHLEVLPPEIGGCVALSVLSLRDNRLAVLPPELAHTAELHVLDVA 366
           + N L ++ P++  C  L  L + +N LA LP  +   + +  L+VA
Sbjct: 141 EHNKLTLICPDLVDCRKLEELDVSNNDLAELPKYIGLLSRMFRLNVA 1

 Score = 56.6 bits (135), Expect = 9e-08,   Method: Compositional matrix adjust.
 Identities = 42/120 (35%), Positives = 65/120 (54%)
 Frame = -2

Query: 117 LSRLPDGFTQLRSLAHLALNDVSLQALPGDVGNLANLVTLELRENLLKSLPASLSFLVKL 176
           L    D + +   L  L L   +L +L   +  L  L  L++ +N L+SLP +L  L  L
Sbjct: 405 LDNTEDRWWEQTDLTKLILASNALTSLGEGLAQLPALTVLDVHDNHLQSLPNALGELENL 226

Query: 177 EQLDLGGNDLEVLPDTLGALPNLRELWLDRNQLSALPPELGNLRRLVCLDVSENRLEELP 236
           ++L++  N L  LP  +G L NL  +  + N+L+ + P+L + R+L  LDVS N L ELP
Sbjct: 225 QKLNISHNQLVELPSCIGRLSNLVSVHAEHNKLTLICPDLVDCRKLEELDVSNNDLAELP 46

 Score = 53.1 bits (126), Expect = 9e-07,   Method: Compositional matrix adjust.
 Identities = 46/144 (31%), Positives = 65/144 (45%)
 Frame = -2

Query: 176 LEQLDLGGNDLEVLPDTLGALPNLRELWLDRNQLSALPPELGNLRRLVCLDVSENRLEEL 235
           L +L L  N L  L + L  LP L  L +  N L +LP  LG L  L  L++S N+L EL
Sbjct: 366 LTKLILASNALTSLGEGLAQLPALTVLDVHDNHLQSLPNALGELENLQKLNISHNQLVEL 187

Query: 236 PVEXXXXXXXXXXXXXXXXXXXXPEGIGQLKQLSILKVDQNRLCEVTEAIGDCENLSELI 295
           P                         IG+L  L  +  + N+L  +   + DC  L EL 
Sbjct: 186 P-----------------------SCIGRLSNLVSVHAEHNKLTLICPDLVDCRKLEELD 76

Query: 296 LTENLLTALPHSLGKLTKLTNLNV 319
           ++ N L  LP  +G L+++  LNV
Sbjct: 75  VSNNDLAELPKYIGLLSRMFRLNV 4

 Score = 53.1 bits (126), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 38/119 (31%), Positives = 59/119 (49%)
 Frame = -2

Query: 84  LVELDVSRNDIPEIPESIKFCKALEIADFSGNPLSRLPDGFTQLRSLAHLALNDVSLQAL 143
           L +L ++ N +  + E +    AL + D   N L  LP+   +L +L  L ++   L  L
Sbjct: 366 LTKLILASNALTSLGEGLAQLPALTVLDVHDNHLQSLPNALGELENLQKLNISHNQLVEL 187

Query: 144 PGDVGNLANLVTLELRENLLKSLPASLSFLVKLEQLDLGGNDLEVLPDTLGALPNLREL 202
           P  +G L+NLV++    N L  +   L    KLE+LD+  NDL  LP  +G L  +  L
Sbjct: 186 PSCIGRLSNLVSVHAEHNKLTLICPDLVDCRKLEELDVSNNDLAELPKYIGLLSRMFRL 10

 Score = 48.1 bits (113), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 36/107 (33%), Positives = 55/107 (51%)
 Frame = -2

Query: 268 LSILKVDQNRLCEVTEAIGDCENLSELILTENLLTALPHSLGKLTKLTNLNVDRNHLEVL 327
           L+ L +  N L  + E +     L+ L + +N L +LP++LG+L  L  LN+  N L  L
Sbjct: 366 LTKLILASNALTSLGEGLAQLPALTVLDVHDNHLQSLPNALGELENLQKLNISHNQLVEL 187

Query: 328 PPEIGGCVALSVLSLRDNRLAVLPPELAHTAELHVLDVAGNRLRSLP 374
           P  IG    L  +    N+L ++ P+L    +L  LDV+ N L  LP
Sbjct: 186 PSCIGRLSNLVSVHAEHNKLTLICPDLVDCRKLEELDVSNNDLAELP 46

 Score = 45.1 bits (105), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 25/65 (38%), Positives = 40/65 (61%)
 Frame = -2

Query: 37  SLEELLLDANQLRELPKPFFRLLNLRKLGLSDNEIQRLPPEVANFMQLVELDVSRNDIPE 96
           +L++L +  NQL ELP    RL NL  +    N++  + P++ +  +L ELDVS ND+ E
Sbjct: 231 NLQKLNISHNQLVELPSCIGRLSNLVSVHAEHNKLTLICPDLVDCRKLEELDVSNNDLAE 52

Query: 97  IPESI 101
           +P+ I
Sbjct: 51  LPKYI 37

 Score = 31.6 bits (70), Expect = 3.0,   Method: Compositional matrix adjust.
 Identities = 26/56 (46%), Positives = 31/56 (55%), Gaps = 1/56 (1%)
 Frame = -2

Query: 337 LSVLSLRDNRLAVLPPELAHTAELHVLDVAGNRLRSLPFALTHL-NLKALWLAENQ 391
           L+ L L  N L  L   LA    L VLDV  N L+SLP AL  L NL+ L ++ NQ
Sbjct: 366 LTKLILASNALTSLGEGLAQLPALTVLDVHDNHLQSLPNALGELENLQKLNISHNQ 199
>05532
          Length = 1607

 Score = 57.8 bits (138), Expect = 3e-08,   Method: Composition-based stats.
 Identities = 36/83 (43%), Positives = 46/83 (55%)
 Frame = +3

Query: 152 NLVTLELRENLLKSLPASLSFLVKLEQLDLGGNDLEVLPDTLGALPNLRELWLDRNQLSA 211
           +L  L L +N L  +   +S L  L  LDL  N L  LP  +G L  LREL L  NQL++
Sbjct: 180 HLTCLYLNDNRLDHISPHVSQLHHLVCLDLSSNQLSSLPSEIGDLTELRELLLYNNQLTS 359

Query: 212 LPPELGNLRRLVCLDVSENRLEE 234
           LP ELG L +L  LD+  N L +
Sbjct: 360 LPFELGRLFQLQNLDIKGNPLSQ 428

 Score = 49.3 bits (116), Expect = 1e-05,   Method: Composition-based stats.
 Identities = 30/82 (36%), Positives = 43/82 (52%)
 Frame = +3

Query: 289 ENLSELILTENLLTALPHSLGKLTKLTNLNVDRNHLEVLPPEIGGCVALSVLSLRDNRLA 348
           ++L+ L L +N L  +   + +L  L  L++  N L  LP EIG    L  L L +N+L 
Sbjct: 177 QHLTCLYLNDNRLDHISPHVSQLHHLVCLDLSSNQLSSLPSEIGDLTELRELLLYNNQLT 356

Query: 349 VLPPELAHTAELHVLDVAGNRL 370
            LP EL    +L  LD+ GN L
Sbjct: 357 SLPFELGRLFQLQNLDIKGNPL 422

 Score = 37.7 bits (86), Expect = 0.036,   Method: Composition-based stats.
 Identities = 24/66 (36%), Positives = 35/66 (53%), Gaps = 1/66 (1%)
 Frame = +3

Query: 327 LPPEIGGCVALSVLSLRDNRLAVLPPELAHTAELHVLDVAGNRLRSLPFALTHLN-LKAL 385
           + PE+     L+ L L DNRL  + P ++    L  LD++ N+L SLP  +  L  L+ L
Sbjct: 153 ISPELFRFQHLTCLYLNDNRLDHISPHVSQLHHLVCLDLSSNQLSSLPSEIGDLTELREL 332

Query: 386 WLAENQ 391
            L  NQ
Sbjct: 333 LLYNNQ 350

 Score = 37.7 bits (86), Expect = 0.043,   Method: Composition-based stats.
 Identities = 27/77 (35%), Positives = 40/77 (51%)
 Frame = +3

Query: 162 LLKSLPASLSFLVKLEQLDLGGNDLEVLPDTLGALPNLRELWLDRNQLSALPPELGNLRR 221
           L++++   L     L  L L  N L+ +   +  L +L  L L  NQLS+LP E+G+L  
Sbjct: 141 LVRNISPELFRFQHLTCLYLNDNRLDHISPHVSQLHHLVCLDLSSNQLSSLPSEIGDLTE 320

Query: 222 LVCLDVSENRLEELPVE 238
           L  L +  N+L  LP E
Sbjct: 321 LRELLLYNNQLTSLPFE 371

 Score = 31.6 bits (70), Expect = 2.6,   Method: Composition-based stats.
 Identities = 21/61 (34%), Positives = 29/61 (47%)
 Frame = +3

Query: 13  HVESVDKRHCSLQVVPEEIYRYSRSLEELLLDANQLRELPKPFFRLLNLRKLGLSDNEIQ 72
           H+  +D     L  +P EI   +  L ELLL  NQL  LP    RL  L+ L +  N + 
Sbjct: 249 HLVCLDLSSNQLSSLPSEIGDLTE-LRELLLYNNQLTSLPFELGRLFQLQNLDIKGNPLS 425

Query: 73  R 73
           +
Sbjct: 426 Q 428
>20073
          Length = 582

 Score = 56.6 bits (135), Expect = 9e-08,   Method: Compositional matrix adjust.
 Identities = 33/77 (42%), Positives = 47/77 (61%), Gaps = 1/77 (1%)
 Frame = +3

Query: 857 GLGFSIAGGK-GSTPYRAGDGGIFISRIAEGGAAHRAGTLQVGDRVLSINGVDMTEARHD 915
           GLGF++ GGK  S+P       I+ISRI  GG A R   L+ GD++LS+NGV +    H+
Sbjct: 3   GLGFNVMGGKEQSSP-------IYISRIIPGGVADRLNCLKRGDQLLSVNGVSVEGEYHE 161

Query: 916 HAVSLLTAASPTISLLL 932
            AV LL  A  ++ L++
Sbjct: 162 KAVELLKLAQGSVRLVV 212

 Score = 40.8 bits (94), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 23/63 (36%), Positives = 39/63 (61%), Gaps = 1/63 (1%)
 Frame = +3

Query: 1000 LGLSIVGGSDHSSHPFGVQDPGVFISKVLPRGLAARCG-LRVGDRILAVNGQDVREATHQ 1058
            LG +++GG + SS         ++IS+++P G+A R   L+ GD++L+VNG  V    H+
Sbjct: 6    LGFNVMGGKEQSSP--------IYISRIIPGGVADRLNCLKRGDQLLSVNGVSVEGEYHE 161

Query: 1059 EAV 1061
            +AV
Sbjct: 162  KAV 170

 Score = 39.7 bits (91), Expect = 0.012,   Method: Compositional matrix adjust.
 Identities = 23/55 (41%), Positives = 36/55 (65%), Gaps = 1/55 (1%)
 Frame = +3

Query: 744 IFISRVSEEGPAARAG-VRVGDKLLEVNGVALQDAEHHEAVEALRGAGAAVQMRV 797
           I+ISR+   G A R   ++ GD+LL VNGV+++   H +AVE L+ A  +V++ V
Sbjct: 48  IYISRIIPGGVADRLNCLKRGDQLLSVNGVSVEGEYHEKAVELLKLAQGSVRLVV 212
>03831
          Length = 1143

 Score = 52.8 bits (125), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 53/215 (24%), Positives = 78/215 (36%), Gaps = 9/215 (4%)
 Frame = +3

Query: 856  KGLGFSIAGGKGSTPYRAGDGGIFISRIAEGGAAHRAGTLQVGDRVLSINGVDMTEARHD 915
             G GF++   KG         G FI ++ EG  A  AG L+ GDR++ +NG ++    H 
Sbjct: 165  NGYGFNLHAEKGKA-------GQFIGKVDEGSPAEAAG-LKAGDRIVEVNGTNIGNENHQ 320

Query: 916  HAVSLLTAASPTISLL-LERETGGTYXXXXXXXXXXX-XXXXXXXXXXXXXXGEXXXXXX 973
              V  + A      LL +++ET   Y                           E      
Sbjct: 321  QVVGRIKAGGDETRLLVVDQETDQHYKEEKRVVRGDLPETRFMTAAREQKDNXENQEAEI 500

Query: 974  XXXXXATALEGPYPVEEICLPRAG---GPLGLSIVGGSDHSSHPFGVQ----DPGVFISK 1026
                 AT    P P     LP       P    +   +D   + F +      PG +I  
Sbjct: 501  AAVVEATNGTEPEPQ---SLPDESSLYAPRLCHLCKWADFDGYGFNLHAEKDKPGQYIGS 671

Query: 1027 VLPRGLAARCGLRVGDRILAVNGQDVREATHQEAV 1061
            V P   A   GL+ GDRI+ VNG+++    H   +
Sbjct: 672  VDPNSPAETGGLKEGDRIIEVNGENIETTNHTAVI 776

 Score = 46.6 bits (109), Expect = 8e-05,   Method: Compositional matrix adjust.
 Identities = 48/220 (21%), Positives = 84/220 (38%), Gaps = 22/220 (10%)
 Frame = +3

Query: 743 GIFISRVSEEGPAARAGVRVGDKLLEVNGVALQDAEHHEAVEALRGAGAAVQMRV----- 797
           G FI +V E  PA  AG++ GD+++EVNG  + +  H + V  ++  G   ++ V     
Sbjct: 207 GQFIGKVDEGSPAEAAGLKAGDRIVEVNGTNIGNENHQQVVGRIKAGGDETRLLVVDQET 386

Query: 798 ---WRE--RMVE---PENAVTITPLRPEDDYSXXXXXXXXXXXXXXXXE-TPVSLRQRHA 848
              ++E  R+V    PE          +D+                  E  P SL    +
Sbjct: 387 DQHYKEEKRVVRGDLPETRFMTAAREQKDNXENQEAEIAAVVEATNGTEPEPQSLPDESS 566

Query: 849 --------ACLVRSEKGLGFSIAGGKGSTPYRAGDGGIFISRIAEGGAAHRAGTLQVGDR 900
                    C      G GF++   K          G +I  +     A   G L+ GDR
Sbjct: 567 LYAPRLCHLCKWADFDGYGFNLHAEKDKP-------GQYIGSVDPNSPAETGG-LKEGDR 722

Query: 901 VLSINGVDMTEARHDHAVSLLTAASPTISLLLERETGGTY 940
           ++ +NG ++    H   +  + +     S+L+  +   +Y
Sbjct: 723 IIEVNGENIETTNHTAVIQNIKSRGDKTSMLVVDKAADSY 842

 Score = 39.7 bits (91), Expect = 0.009,   Method: Compositional matrix adjust.
 Identities = 23/62 (37%), Positives = 31/62 (50%), Gaps = 4/62 (6%)
 Frame = +3

Query: 1004 IVGGSDHSSHPFGVQ----DPGVFISKVLPRGLAARCGLRVGDRILAVNGQDVREATHQE 1059
            IV  SD + + F +       G FI KV     A   GL+ GDRI+ VNG ++    HQ+
Sbjct: 144  IVRWSDFNGYGFNLHAEKGKAGQFIGKVDEGSPAEAAGLKAGDRIVEVNGTNIGNENHQQ 323

Query: 1060 AV 1061
             V
Sbjct: 324  VV 329

 Score = 37.4 bits (85), Expect = 0.048,   Method: Compositional matrix adjust.
 Identities = 17/58 (29%), Positives = 29/58 (50%)
 Frame = +3

Query: 740 DDEGIFISRVSEEGPAARAGVRVGDKLLEVNGVALQDAEHHEAVEALRGAGAAVQMRV 797
           D  G +I  V    PA   G++ GD+++EVNG  ++   H   ++ ++  G    M V
Sbjct: 645 DKPGQYIGSVDPNSPAETGGLKEGDRIIEVNGENIETTNHTAVIQNIKSRGDKTSMLV 818
>30747
          Length = 1168

 Score = 52.8 bits (125), Expect = 1e-06,   Method: Composition-based stats.
 Identities = 63/239 (26%), Positives = 100/239 (41%)
 Frame = +3

Query: 135 LNDVSLQALPGDVGNLANLVTLELRENLLKSLPASLSFLVKLEQLDLGGNDLEVLPDTLG 194
           L+   + A+P D+     L  L++  N +  +   L F   L  L L  N +  +   L 
Sbjct: 216 LHGTEITAVP-DLEKFRKLRVLDVSGNYITKI-QHLEFTQDLRDLKLYDNKVSQV-QGLE 386

Query: 195 ALPNLRELWLDRNQLSALPPELGNLRRLVCLDVSENRLEELPVEXXXXXXXXXXXXXXXX 254
           +L  L  L L  NQ+ +L   L  L++L CL +  NRL +L                   
Sbjct: 387 SLKELCSLQLQYNQIESLGKGLNALKKLKCLRLDSNRLTKLDTNE--------------- 521

Query: 255 XXXXPEGIGQLKQLSILKVDQNRLCEVTEAIGDCENLSELILTENLLTALPHSLGKLTKL 314
                  +     +S L +  N +  ++ A+    NL EL ++ N +  L   L +  KL
Sbjct: 522 -------LLSCVNISTLDLSNNHITNLS-ALSYLPNLEELFVSGNSIQKLT-DLHRCKKL 674

Query: 315 TNLNVDRNHLEVLPPEIGGCVALSVLSLRDNRLAVLPPELAHTAELHVLDVAGNRLRSL 373
           + L++ RN L V    I G  AL  L + DNRL  +   L     L  L++ GN++  L
Sbjct: 675 SELDLSRNRL-VDISGISGLPALQTLDMSDNRLKSV-TSLGKLKSLETLNLNGNQISEL 845
>29705
          Length = 674

 Score = 51.6 bits (122), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 27/81 (33%), Positives = 48/81 (59%)
 Frame = -1

Query: 856 KGLGFSIAGGKGSTPYRAGDGGIFISRIAEGGAAHRAGTLQVGDRVLSINGVDMTEARHD 915
           +G G     GKG+  +  GD GIFI+++ EGG+A + G + V DR+L++N  ++ +  H+
Sbjct: 422 QGSGIQHCRGKGNQ-HIPGDNGIFITKVIEGGSAEQDGRIAVMDRLLAVNEHNLEDVTHE 246

Query: 916 HAVSLLTAASPTISLLLERET 936
            AV+ L +    + L + + T
Sbjct: 245 EAVAALKSTGDVVRLTIAKPT 183

 Score = 44.3 bits (103), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 22/46 (47%), Positives = 33/46 (71%), Gaps = 1/46 (2%)
 Frame = -1

Query: 1019 DPGVFISKVLPRGLAARCG-LRVGDRILAVNGQDVREATHQEAVSA 1063
            D G+FI+KV+  G A + G + V DR+LAVN  ++ + TH+EAV+A
Sbjct: 368  DNGIFITKVIEGGSAEQDGRIAVMDRLLAVNEHNLEDVTHEEAVAA 231

 Score = 38.1 bits (87), Expect = 0.031,   Method: Compositional matrix adjust.
 Identities = 22/66 (33%), Positives = 30/66 (45%)
 Frame = -1

Query: 1110 GNPCDPTDEGIFISKVSPTXXXXXXXXXXXXXXXXEVNQQSLLGLTHAEAVQLLRSVGDT 1169
            GN   P D GIFI+KV                    VN+ +L  +TH EAV  L+S GD 
Sbjct: 389  GNQHIPGDNGIFITKVIEGGSAEQDGRIAVMDRLLAVNEHNLEDVTHEEAVAALKSTGDV 210

Query: 1170 LTVLVC 1175
            + + + 
Sbjct: 209  VRLTIA 192
>01502
          Length = 1949

 Score = 46.6 bits (109), Expect = 9e-05,   Method: Composition-based stats.
 Identities = 22/60 (36%), Positives = 39/60 (65%)
 Frame = +1

Query: 741 DEGIFISRVSEEGPAARAGVRVGDKLLEVNGVALQDAEHHEAVEALRGAGAAVQMRVWRE 800
           D+GI+++ + E  PAAR G+++ DK+L++NG       H +AVE +R     ++M V+R+
Sbjct: 28  DKGIYVTFIYENSPAARCGLQLHDKILQLNGKDFTVVTHKQAVENIR-KKPVLKMLVYRK 204

 Score = 44.3 bits (103), Expect = 4e-04,   Method: Composition-based stats.
 Identities = 18/43 (41%), Positives = 30/43 (69%)
 Frame = +1

Query: 1019 DPGVFISKVLPRGLAARCGLRVGDRILAVNGQDVREATHQEAV 1061
            D G++++ +     AARCGL++ D+IL +NG+D    TH++AV
Sbjct: 28   DKGIYVTFIYENSPAARCGLQLHDKILQLNGKDFTVVTHKQAV 156
>02951
          Length = 1076

 Score = 46.2 bits (108), Expect = 1e-04,   Method: Composition-based stats.
 Identities = 22/60 (36%), Positives = 39/60 (65%)
 Frame = +2

Query: 741 DEGIFISRVSEEGPAARAGVRVGDKLLEVNGVALQDAEHHEAVEALRGAGAAVQMRVWRE 800
           D+GI+++ + E  PAAR G+++ DK+L++NG       H +AVE +R     ++M V+R+
Sbjct: 14  DKGIYVTFIYENSPAARCGLQLHDKILQLNGKDFTVVTHKQAVENIR-KKPVLKMLVYRK 190

 Score = 45.1 bits (105), Expect = 2e-04,   Method: Composition-based stats.
 Identities = 19/46 (41%), Positives = 31/46 (67%)
 Frame = +2

Query: 1016 GVQDPGVFISKVLPRGLAARCGLRVGDRILAVNGQDVREATHQEAV 1061
            G  D G++++ +     AARCGL++ D+IL +NG+D    TH++AV
Sbjct: 5    GYPDKGIYVTFIYENSPAARCGLQLHDKILQLNGKDFTVVTHKQAV 142
>27345
          Length = 496

 Score = 43.1 bits (100), Expect = 0.001,   Method: Composition-based stats.
 Identities = 20/64 (31%), Positives = 36/64 (56%)
 Frame = +3

Query: 872 RAGDGGIFISRIAEGGAAHRAGTLQVGDRVLSINGVDMTEARHDHAVSLLTAASPTISLL 931
           R G  GIFI  + +GGAA + G +QV D+++ ++G  +      +A S+L   S  ++  
Sbjct: 9   RPGKLGIFIKTLTDGGAAQKDGRIQVNDQIIEVDGKSLVGVTQAYAASVLRNTSGQVTFH 188

Query: 932 LERE 935
           + R+
Sbjct: 189 IGRD 200
>37214
          Length = 316

 Score = 40.4 bits (93), Expect = 0.006,   Method: Composition-based stats.
 Identities = 32/100 (32%), Positives = 47/100 (47%), Gaps = 3/100 (3%)
 Frame = -2

Query: 90  SRNDIPEIPESIKFCKA-LEIADFSGNPLSRLPDGFTQLRSLAHLALNDVSLQAL-PGDV 147
           +R +   +  +  FCK   +  D S     R  D F  L  L HL+     L +L PG +
Sbjct: 300 TRTEEAILTATFHFCKC*SDQTDMSEVGEGRFMDLFGYLVHLTHLSARKCFLDSLFPGML 121

Query: 148 GNLANLVTLELRENLLKSLPASL-SFLVKLEQLDLGGNDL 186
              +NL TL+L +N + S+P  +   L  L  LDL GN +
Sbjct: 120 HAFSNLSTLQLSDNKISSIPEGVFDSLHNLSHLDLSGNPI 1
>39267
          Length = 456

 Score = 39.7 bits (91), Expect = 0.010,   Method: Compositional matrix adjust.
 Identities = 24/75 (32%), Positives = 41/75 (54%)
 Frame = +1

Query: 857 GLGFSIAGGKGSTPYRAGDGGIFISRIAEGGAAHRAGTLQVGDRVLSINGVDMTEARHDH 916
           GLGF+I+G            GI++S++   G A  +G + VGDR+ S+  +      ++ 
Sbjct: 115 GLGFNISGNMRD--------GIYVSQLHNRGPASESGKIHVGDRIQSVT-IAYDNIVYED 267

Query: 917 AVSLLTAASPTISLL 931
           A+++L+ ASP   LL
Sbjct: 268 ALTILSYASPYPVLL 312
>20775
          Length = 1020

 Score = 38.9 bits (89), Expect = 0.018,   Method: Composition-based stats.
 Identities = 38/137 (27%), Positives = 58/137 (42%), Gaps = 12/137 (8%)
 Frame = -3

Query: 111 DFSGNPLSRLPDGFTQLRSLAHLALNDVSLQALPGDVGNLANLVTLELRENLLKSLPASL 170
           D SGN LS LPD F     +  L L + +  ALP        L  +E    L  S  A +
Sbjct: 571 DLSGNNLSTLPDNFLNGEIIDSLILKNNNFTALP------VALTKVEHXRRLDVSFSALV 410

Query: 171 SF-------LVKLEQLDLGGNDL----EVLPDTLGALPNLRELWLDRNQLSALPPE-LGN 218
           SF       +  LE +D+  N L     V   + G +   +EL L  N +  +       
Sbjct: 409 SFSFDILENVSGLEMVDMSSNKLLYASTVGESSAGVMLGXKELNLASNAIDRIEDGFFSR 230

Query: 219 LRRLVCLDVSENRLEEL 235
           + +L  L++S+N L ++
Sbjct: 229 MDKLTTLNLSDNHLSQV 179

 Score = 38.5 bits (88), Expect = 0.022,   Method: Composition-based stats.
 Identities = 48/189 (25%), Positives = 71/189 (37%), Gaps = 7/189 (3%)
 Frame = -3

Query: 166 LPASLSFLVKLEQLDLGGNDLEVLPDTLGALPNLRELWLDRNQLSALPPELGNLRRLVCL 225
           L  S +  V L  LDL GN+L  LPD       +  L L  N  +ALP  L  +     L
Sbjct: 613 LNTSFANSVTLINLDLSGNNLSTLPDNFLNGEIIDSLILKNNNFTALPVALTKVEHXRRL 434

Query: 226 DVSENRLEELPVEXXXXXXXXXXXXXXXXXXXXPEGIGQLKQLSILKVDQNRLCEVT--- 282
           DVS + L     +                       +  +  L ++ +  N+L   +   
Sbjct: 433 DVSFSALVSFSFDI----------------------LENVSGLEMVDMSSNKLLYASTVG 320

Query: 283 -EAIGDCENLSELILTENLLTALPHS-LGKLTKLTNLNVDRNHL-EVLPPEIGGCV-ALS 338
             + G      EL L  N +  +      ++ KLT LN+  NHL +V      G   +LS
Sbjct: 319 ESSAGVMLGXKELNLASNAIDRIEDGFFSRMDKLTTLNLSDNHLSQVTQTTFSGLAQSLS 140

Query: 339 VLSLRDNRL 347
            L L +  L
Sbjct: 139 TLDLSNTSL 113
>38751
          Length = 329

 Score = 38.9 bits (89), Expect = 0.018,   Method: Composition-based stats.
 Identities = 25/64 (39%), Positives = 33/64 (51%), Gaps = 1/64 (1%)
 Frame = +3

Query: 862 IAGGKG-STPYRAGDGGIFISRIAEGGAAHRAGTLQVGDRVLSINGVDMTEARHDHAVSL 920
           I GGK   TP       I +  I EG  A + G L +GDR+L +NG D T   H  AV++
Sbjct: 9   IKGGKEYGTP-------IVVYVIEEGCQAEQQG-LNIGDRILDVNGTDFTHLTHAEAVTI 164

Query: 921 LTAA 924
           +  A
Sbjct: 165 MRNA 176

 Score = 37.0 bits (84), Expect = 0.060,   Method: Composition-based stats.
 Identities = 17/30 (56%), Positives = 20/30 (66%)
 Frame = +3

Query: 1033 AARCGLRVGDRILAVNGQDVREATHQEAVS 1062
            A + GL +GDRIL VNG D    TH EAV+
Sbjct: 72   AEQQGLNIGDRILDVNGTDFTHLTHAEAVT 161

 Score = 35.4 bits (80), Expect = 0.20,   Method: Composition-based stats.
 Identities = 18/42 (42%), Positives = 25/42 (59%), Gaps = 1/42 (2%)
 Frame = +3

Query: 749 VSEEG-PAARAGVRVGDKLLEVNGVALQDAEHHEAVEALRGA 789
           V EEG  A + G+ +GD++L+VNG       H EAV  +R A
Sbjct: 51  VIEEGCQAEQQGLNIGDRILDVNGTDFTHLTHAEAVTIMRNA 176
>08480
          Length = 698

 Score = 38.5 bits (88), Expect = 0.020,   Method: Compositional matrix adjust.
 Identities = 17/45 (37%), Positives = 27/45 (60%)
 Frame = -1

Query: 887 GAAHRAGTLQVGDRVLSINGVDMTEARHDHAVSLLTAASPTISLL 931
           G A  +G L+ GD++LS+N VD+  A H+ A   L  A  T+ ++
Sbjct: 698 GPADLSGDLRRGDKILSVNDVDVERATHEQAAQALKRAGDTVEII 564

 Score = 33.9 bits (76), Expect = 0.63,   Method: Compositional matrix adjust.
 Identities = 15/26 (57%), Positives = 19/26 (73%)
 Frame = -1

Query: 1038 LRVGDRILAVNGQDVREATHQEAVSA 1063
            LR GD+IL+VN  DV  ATH++A  A
Sbjct: 674  LRRGDKILSVNDVDVERATHEQAAQA 597
>08106
          Length = 997

 Score = 37.7 bits (86), Expect = 0.035,   Method: Compositional matrix adjust.
 Identities = 26/63 (41%), Positives = 35/63 (55%), Gaps = 3/63 (4%)
 Frame = +2

Query: 331 IGGCVALSVLSLRDNRLAVLPPELAHTAELHVLDVAGNRLRSLPFALTHLN---LKALWL 387
           +G CV+L+ L LRDN+L  L        EL  ++V GN L S+  A    +   L+AL L
Sbjct: 32  LGRCVSLATLHLRDNQLENLDGFTEELKELQYVNVRGNLLTSIKEAAKLKDLPLLRALSL 211

Query: 388 AEN 390
           AEN
Sbjct: 212 AEN 220
>26154
          Length = 446

 Score = 37.4 bits (85), Expect = 0.055,   Method: Compositional matrix adjust.
 Identities = 17/49 (34%), Positives = 29/49 (59%)
 Frame = -3

Query: 887 GAAHRAGTLQVGDRVLSINGVDMTEARHDHAVSLLTAASPTISLLLERE 935
           G+AHR G++Q GD++++IN V +     D A  LL      + L ++R+
Sbjct: 408 GSAHRCGSIQAGDKLMAINDVRLDTCTVDDATHLLELPDELVKLKVQRD 262
>37239
          Length = 453

 Score = 33.1 bits (74), Expect = 0.94,   Method: Compositional matrix adjust.
 Identities = 23/65 (35%), Positives = 35/65 (53%), Gaps = 1/65 (1%)
 Frame = -2

Query: 752 EGPAAR-AGVRVGDKLLEVNGVALQDAEHHEAVEALRGAGAAVQMRVWRERMVEPENAVT 810
           + PAAR A + VGD+LLE+NG  L    H  A  A+  +  A  +++   R  +  + + 
Sbjct: 446 DSPAARDARIHVGDELLEINGNLLHGRCHLNA-SAIVKSVTAPDVKLVVNRRADSLDRIA 270

Query: 811 ITPLR 815
           I PLR
Sbjct: 269 IKPLR 255
>17298
          Length = 476

 Score = 33.1 bits (74), Expect = 0.95,   Method: Composition-based stats.
 Identities = 13/34 (38%), Positives = 25/34 (73%)
 Frame = +3

Query: 205 DRNQLSALPPELGNLRRLVCLDVSENRLEELPVE 238
           + N ++ +P +L +L  L CL++++N++EELP E
Sbjct: 261 NNNAITDVPADLSSLPHLNCLNLADNQIEELPNE 362

 Score = 32.7 bits (73), Expect = 1.1,   Method: Composition-based stats.
 Identities = 17/64 (26%), Positives = 34/64 (53%)
 Frame = +3

Query: 308 LGKLTKLTNLNVDRNHLEVLPPEIGGCVALSVLSLRDNRLAVLPPELAHTAELHVLDVAG 367
           L K    +++  + N +  +P ++     L+ L+L DN++  LP EL     L  L ++G
Sbjct: 225 LAKCLTGSDIIANNNAITDVPADLSSLPHLNCLNLADNQIEELPNELCECTRLKELKLSG 404

Query: 368 NRLR 371
           N+++
Sbjct: 405 NKIK 416
>14078
          Length = 1045

 Score = 32.3 bits (72), Expect = 1.8,   Method: Composition-based stats.
 Identities = 23/64 (35%), Positives = 34/64 (53%), Gaps = 4/64 (6%)
 Frame = -1

Query: 331 IGGCVALSVLSLRDNRLAVLPPELAHTAELHVLDVAGNRLRSLPFALTHLN----LKALW 386
           +G C  L+ L LRDN+L  L        EL  +++ GN + S+   +T L     L+AL 
Sbjct: 313 LGRCAGLTTLHLRDNQLESLDGFTDDLKELQYVNLRGNLMSSVK-EMTKLKCLSFLRALA 137

Query: 387 LAEN 390
           L+EN
Sbjct: 136 LSEN 125
>15446
          Length = 401

 Score = 30.0 bits (66), Expect = 8.4,   Method: Composition-based stats.
 Identities = 30/106 (28%), Positives = 45/106 (42%), Gaps = 3/106 (2%)
 Frame = -3

Query: 288 CENLSELI-LTENLLTALPHSLGKLTKLTNLNVDRNHLEVLPP-EIGGCVALSVLSLRDN 345
           C  L  LI  +E  L  +P+ L   +  T L +  N +  L   +  G   L  L L  N
Sbjct: 342 CACLGILIDCSERGLVEVPNDLQLRSWGTRLELQSNGITSLEAGDFKGLHMLEELYLSHN 163

Query: 346 RLAVLPPELAHT-AELHVLDVAGNRLRSLPFALTHLNLKALWLAEN 390
            +  +   +     +LH L +  N+L  +P    HLN+  L LA N
Sbjct: 162 DITFINGSIFQDLIKLHTLKITHNKLTEMPVFPRHLNITELSLAHN 25
>17623
          Length = 687

 Score = 29.6 bits (65), Expect = 9.9,   Method: Composition-based stats.
 Identities = 23/80 (28%), Positives = 39/80 (48%), Gaps = 2/80 (2%)
 Frame = +2

Query: 78  VANFMQLVELDVSRNDIPEIPESIKFCKALEIADFSGNPLSRLPD--GFTQLRSLAHLAL 135
           + + + L EL+++ N I ++  S+     LE  + SGNP+S L D     +L  L  +++
Sbjct: 314 LTHLVNLKELNLAENKIEKLGHSLDSNIHLEDLNLSGNPISSLRDVTNLVRLPQLQSVSM 493

Query: 136 NDVSLQALPGDVGNLANLVT 155
            D   +  P  V  L N  T
Sbjct: 494 KDPLYRPCP--VSQLCNYST 547
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|224809371|ref|NP_032468.2| kinesin family member 2A
isoform 1 [Mus musculus]
         (716 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

33215                                                                 119   4e-27
12048                                                                 118   1e-26
13148                                                                  93   6e-26
02896                                                                  90   3e-18
38050                                                                  47   1e-17
28434                                                                  83   3e-16
11818                                                                  80   2e-15
34899                                                                  60   4e-09
15043                                                                  59   6e-09
14618                                                                  56   5e-08
34477                                                                  55   7e-08
17748                                                                  54   2e-07
36593                                                                  39   0.008
18684                                                                  37   0.039
03912                                                                  35   0.082
38061                                                                  33   0.44 
10615                                                                  30   4.6  
>33215
          Length = 696

 Score =  119 bits (298), Expect = 4e-27,   Method: Compositional matrix adjust.
 Identities = 79/203 (38%), Positives = 114/203 (56%), Gaps = 11/203 (5%)
 Frame = +1

Query: 338 FFEIYSGKVFDLLNR--KTKLRVLEDGKQQVQVVGLQEREVKCVEDVLKLIDIGNSCRTS 395
           + EIY  ++ DLL++    +L +       V V  L     K V ++  ++++GN  R+ 
Sbjct: 1   YLEIYQEEIRDLLSKDQSKRLELKXRPDTGVYVKDLSSFVTKSVREIEHVMNVGNQNRSV 180

Query: 396 GQTSANAHSSRSHAVFQIILR-----RKGKLH---GKFSLIDLAGNERGADTSSADRQTR 447
           G T+ N HSSRSHA+F I +        G+ H   GK +++DLAG+ER A T +   + +
Sbjct: 181 GATNMNEHSSRSHAIFIITVECSEIGADGENHIRVGKLNMVDLAGSERQAKTGATGDRLK 360

Query: 448 LEGAEINKSLLALKECIRALGRNK-PHTPFRASKLTQVLRDSFIGENSRTCMIATISPGM 506
            E  +IN SL AL   I AL   K  H P+R SKLT++L+DS +G NS+T M+A I P  
Sbjct: 361 -EATKINLSLSALSNVISALVDAKTTHIPYRDSKLTRLLQDS-LGGNSKTTMVANIGPAS 534

Query: 507 ASCENTLNTLRYANRVKEFGISP 529
            + + TL TLRYANR K     P
Sbjct: 535 YNFDETLTTLRYANRAKSIKNKP 603
>12048
          Length = 1162

 Score =  118 bits (295), Expect = 1e-26,   Method: Compositional matrix adjust.
 Identities = 95/296 (32%), Positives = 142/296 (47%), Gaps = 15/296 (5%)
 Frame = +2

Query: 242 ENQTFRFDYAFDDSAPNEMVYRFTARPLVETIFERGMATCFAYGQTGSGKTHTMGGDFSG 301
           EN  FRFD  FD         R        T F+  M       + G GKT T+ G   G
Sbjct: 272 ENYKFRFDKCFDQKQTKMKCSRM*PSLS*TTSFKATMGQYSLMARRGGGKTFTITG---G 442

Query: 302 KNQDCSKGIYALAARDVFLMLKKPNYKKLELQVYATFFEIYSGKVFDLLNRKT------- 354
             +   +G+   +   ++   +K    +L   V+ ++ EIY+   +DLL+ K        
Sbjct: 443 AERYMDRGLIPRSLSYIYEQTEKN--PELSFTVHISYLEIYNDSGYDLLDPKHEAAKLED 616

Query: 355 --KLRVLEDGKQQVQVVGLQEREVKCVEDVLKLIDIGNSCRTSGQTSANAHSSRSHAVF- 411
             K+ +LED  Q + +  L   +    E+ L L+ +G++ R   +T  N  SSRSH +F 
Sbjct: 617 LPKVNLLEDSDQNIHLRNLSVHQANSEEEALNLLFLGDTNRMIAETPMNQASSRSHCIFT 796

Query: 412 -QIILRRKGKL---HGKFSLIDLAGNERGADTSSADRQTRLEGAEINKSLLALKECIRAL 467
             I  R  G       K+ L+DLAG+ER A T+  + Q   E   IN SL  L+  I AL
Sbjct: 797 IHITTRETGSATIRRAKYHLVDLAGSERVAKTN-VNGQLLTEARYINSSLHFLELVIIAL 973

Query: 468 G-RNKPHTPFRASKLTQVLRDSFIGENSRTCMIATISPGMASCENTLNTLRYANRV 522
             +++ H P+R S +T VLRDS +G N  T MIAT S    + + +++T R+A RV
Sbjct: 974 SEKSRQHVPYRNSMMTSVLRDS-LGGNCMTTMIATCSMEKRNMDESISTCRFAQRV 1138
>13148
          Length = 653

 Score = 93.2 bits (230), Expect(2) = 6e-26,   Method: Composition-based stats.
 Identities = 67/177 (37%), Positives = 96/177 (54%), Gaps = 11/177 (6%)
 Frame = -3

Query: 291 KTHTMGGDFSGKNQDCSKGIYALAARDVFLMLKKPNY-----KKLELQVYATFFEIYSGK 345
           KTHTM G    ++    +GI     +D+F      NY     + LE  +  ++FEIY  K
Sbjct: 501 KTHTMEGVLGNESL---QGIIPRIVQDIF------NYIYGMDENLEFHIKVSYFEIYMDK 349

Query: 346 VFDLLN-RKTKLRVLEDGKQQVQVVGLQEREVKCVEDVLKLIDIGNSCRTSGQTSANAHS 404
           + DLL+  KT L V ED  +   V G  ER V   E+V++++D G S R    T+ N HS
Sbjct: 348 IRDLLDVTKTNLSVHEDKNRVPYVKGCTERFVSSPEEVMEVVDEGKSNRHVAVTNMNEHS 169

Query: 405 SRSHAVFQIILRRKG-----KLHGKFSLIDLAGNERGADTSSADRQTRLEGAEINKS 456
           SRSH+VF I ++++      KLHGK  L+DLAG+E+ + T  A+     E   IN+S
Sbjct: 168 SRSHSVFLIHVKQENVDSEKKLHGKLYLVDLAGSEKVSKT-GAEGAVLDEAKNINRS 1

 Score = 43.5 bits (101), Expect(2) = 6e-26,   Method: Composition-based stats.
 Identities = 22/51 (43%), Positives = 27/51 (52%)
 Frame = -1

Query: 244 QTFRFDYAFDDSAPNEMVYRFTARPLVETIFERGMATCFAYGQTGSGKTHT 294
           + F FD     +   E VY  TA+P+V  +      T FAYGQT SGK HT
Sbjct: 641 KVFMFDKVLKPNVTQEYVYTVTAKPIVADVLSGYNGTIFAYGQTSSGK-HT 492
>02896
          Length = 2076

 Score = 90.1 bits (222), Expect = 3e-18,   Method: Compositional matrix adjust.
 Identities = 59/161 (36%), Positives = 86/161 (53%), Gaps = 8/161 (4%)
 Frame = +1

Query: 370 GLQEREVKCVEDVLKLIDIGNSCRTSGQTSANAHSSRSHAVFQIILRRKGKLHG------ 423
           GL     +  E+ L L+  G + R+    S N  SSRSH +F + L  + ++        
Sbjct: 22  GLASHLAQNEEEALNLLFEGETNRSIAAHSLNRMSSRSHCIFTVYLESRSRVQSSAKYTV 201

Query: 424 -KFSLIDLAGNERGADTSSADRQTRLEGAEINKSLLALKECIRALG-RNKPHTPFRASKL 481
            K + +DLAG+ER   + S  +    E   INKSL  L++ + AL  +N+ H PFR SKL
Sbjct: 202 SKLNFVDLAGSERIGKSKSEGKMV-TEAMYINKSLSFLEQVVIALADKNRDHIPFRQSKL 378

Query: 482 TQVLRDSFIGENSRTCMIATISPGMASCENTLNTLRYANRV 522
           T  L+DS IG N  T +IA +    A  E T++TLR+A R+
Sbjct: 379 THYLKDS-IGGNCNTVLIANVWGERAQLEETVSTLRFATRM 498
>38050
          Length = 809

 Score = 46.6 bits (109), Expect(3) = 1e-17,   Method: Compositional matrix adjust.
 Identities = 34/99 (34%), Positives = 50/99 (50%), Gaps = 8/99 (8%)
 Frame = -2

Query: 352 RKTKLRVLEDGKQQVQVVGLQEREVKCVEDVLKLIDIGNSCRTSGQTSANAHSSRSHAVF 411
           +K  LR+ +  K      GLQ   V   ED+ K ++ G + RT   T+ NA SSR+H + 
Sbjct: 745 KKGGLRIRQHPKNGFYADGLQVVPVVSYEDIEKKMEAGTTNRTVAATNMNATSSRAHTIV 566

Query: 412 QIILRRKGKLHGK--------FSLIDLAGNERGADTSSA 442
            I   +K K             +L+DLAG+ER AD++ A
Sbjct: 565 GITFMQKFKNAAGEETTKSALINLVDLAGSER-ADSTGA 452

 Score = 42.7 bits (99), Expect(3) = 1e-17,   Method: Compositional matrix adjust.
 Identities = 18/35 (51%), Positives = 25/35 (71%)
 Frame = -3

Query: 491 GENSRTCMIATISPGMASCENTLNTLRYANRVKEF 525
           G NS+T M+A +SP   + E TL+TLRYA+R K+ 
Sbjct: 300 GWNSKTIMVAALSPADINYEETLSTLRYADRAKQI 196

 Score = 38.5 bits (88), Expect(3) = 1e-17,   Method: Compositional matrix adjust.
 Identities = 21/47 (44%), Positives = 27/47 (57%), Gaps = 4/47 (8%)
 Frame = -1

Query: 449 EGAEINKSLLALKECIRAL----GRNKPHTPFRASKLTQVLRDSFIG 491
           EGA IN+SL  L  CI AL    G      PFR S LT++L+++  G
Sbjct: 434 EGAAINQSLSCLGNCISALADKAGGKNVKVPFRDSALTKLLKNALGG 294
>28434
          Length = 777

 Score = 83.2 bits (204), Expect = 3e-16,   Method: Compositional matrix adjust.
 Identities = 50/105 (47%), Positives = 67/105 (63%), Gaps = 4/105 (3%)
 Frame = +2

Query: 429 DLAGNERGADT-SSADRQTRLEGAEINKSLLALKECIRALGRN---KPHTPFRASKLTQV 484
           DLAG+ER   T +  DR    EG  IN+ LLAL   I ALG +   + H P+R SKLT++
Sbjct: 62  DLAGSERAKRTRAEGDRFK--EGVNINRGLLALGNVISALGEDVQKRGHIPYRDSKLTRL 235

Query: 485 LRDSFIGENSRTCMIATISPGMASCENTLNTLRYANRVKEFGISP 529
           L+DS +G NS T M+A +SP  ++ E TLNTLRYA+R ++    P
Sbjct: 236 LQDS-LGGNSHTLMVACVSPADSNMEETLNTLRYADRARKIKNKP 367
>11818
          Length = 657

 Score = 80.5 bits (197), Expect = 2e-15,   Method: Compositional matrix adjust.
 Identities = 59/174 (33%), Positives = 94/174 (54%), Gaps = 12/174 (6%)
 Frame = -1

Query: 289 SGKTHTMGG--DFSGKNQDCSKGIYALAARDVF-LMLKKPNYKKLELQVYATFFEIYSGK 345
           SGKT+TMGG  D +  + D   GI      D+F  + ++ +Y     +V  ++ EIY+  
Sbjct: 657 SGKTYTMGGCYDAALSHDDDLVGIIPRILGDLFNGIAERSDYT---FKVTVSYLEIYNED 487

Query: 346 VFDLL---NRKTKLRVLEDGKQQVQVVGLQEREVKCVEDVLKLIDIGNSCRTSGQTSANA 402
           + DLL   +++  L + E+   ++++ GL+E EV  +ED L  +  G   RT+G T+ N 
Sbjct: 486 LLDLLCLPSQRQPLSIREEMNGEIKIKGLKEVEVGSLEDTLMCLSQGARSRTTGATAMND 307

Query: 403 HSSRSHAVFQIILRRKGK------LHGKFSLIDLAGNERGADTSSADRQTRLEG 450
            SSRSHA+F + + +  K         KF L+DLAG+ER        ++TR EG
Sbjct: 306 TSSRSHAIFTVHIEKSKKEDMNDHCIAKFHLVDLAGSERA-------KKTRAEG 166

 Score = 38.5 bits (88), Expect = 0.010,   Method: Composition-based stats.
 Identities = 28/70 (40%), Positives = 36/70 (51%), Gaps = 17/70 (24%)
 Frame = -3

Query: 444 RQTRLEGAEINKS--------------LLALKECIRALGRN---KPHTPFRASKLTQVLR 486
           R  RL   + NKS              LLAL   I ALG +   + H P+R SKLT++L+
Sbjct: 211 RPCRLRAGQENKS*GRQIQRRCKHYRGLLALGNVISALGEDVQKRGHIPYRDSKLTRLLQ 32

Query: 487 DSFIGENSRT 496
           DS +G NS T
Sbjct: 31  DS-LGGNSHT 5
>34899
          Length = 564

 Score = 59.7 bits (143), Expect = 4e-09,   Method: Compositional matrix adjust.
 Identities = 48/164 (29%), Positives = 76/164 (46%), Gaps = 1/164 (0%)
 Frame = +3

Query: 248 FDYAFDDSAPNEMVYRFTARPLVETIFERGMATCFAYGQTGSGKTHTMGGDFSGKNQDCS 307
            D A+   A N  +Y+     +V+   E    T  A+G TGSGK+  M G+      D  
Sbjct: 6   LDGAYGPDAKNGQIYQEKCDSMVQRALEGYNVTIMAFGATGSGKSFLMNGN------DQE 167

Query: 308 KGIYALAARDVFLMLKKPNYKKLELQVYATFFEIYSGKVFDLLNRKTK-LRVLEDGKQQV 366
            G+  +  + +F  L++ + K  E  V A+F EI   K+ DLLN   + + V +   + +
Sbjct: 168 IGVAPMVIQQLFQHLRQRSNK--ESMVTASFVEILDEKMTDLLNPHNRPMAVRQHVIKGI 341

Query: 367 QVVGLQEREVKCVEDVLKLIDIGNSCRTSGQTSANAHSSRSHAV 410
            V GL E   +  E++ +L + G   R  G T   AH +R  A 
Sbjct: 342 FVDGLSEMVARTGEELSQLYEQGRRARRMGATDIKAHRARYDAA 473
>15043
          Length = 973

 Score = 58.9 bits (141), Expect = 6e-09,   Method: Compositional matrix adjust.
 Identities = 45/144 (31%), Positives = 71/144 (49%), Gaps = 9/144 (6%)
 Frame = +2

Query: 389 GNSCRTSGQTSANAHSSRSHAVFQIILRRKGKLHGKFS------LIDLAGNERGADTSSA 442
           G   R  G T   AH +R+HAVF I + +K +   K        L++LAG E  AD +  
Sbjct: 26  GRRARRMGATDIKAHRARAHAVFTITVEQKERQSSKVGVRANIMLVELAGCE-AADATD- 199

Query: 443 DRQTRLEGAEINKSLLALKECIRALGRNKP---HTPFRASKLTQVLRDSFIGENSRTCMI 499
                    +I      +   ++ALG +K    H P+R S +T++L+D+ +G N+ T M+
Sbjct: 200 --------PKILAGTQGVVNVLKALGDSKQIGGHVPYRESLVTRLLQDT-LGGNAMTLML 352

Query: 500 ATISPGMASCENTLNTLRYANRVK 523
            T+SP   S + T + L+Y    K
Sbjct: 353 VTVSPLDKSYQTTQSALQYGQFAK 424
>14618
          Length = 724

 Score = 56.2 bits (134), Expect = 5e-08,   Method: Compositional matrix adjust.
 Identities = 47/165 (28%), Positives = 74/165 (44%), Gaps = 6/165 (3%)
 Frame = -2

Query: 246 FRFDYAFDDSAPNEMVYRFTARPLVETIFERGMATCFAYGQTGSGKTHTMGGDFSGKNQD 305
           F FD  F      + V+   ++ LV++  +      FAYGQTGSGKT+TM G   G   +
Sbjct: 483 FSFDRVFHPDNTQQDVFEEISQ-LVQSALDGYNVCIFAYGQTGSGKTYTMEGGLVG--DE 313

Query: 306 CSKGIYALAARDVFLMLKKPNYKKLELQVYATFFEIYSGKVFDLL------NRKTKLRVL 359
            +KG+   A   +F   ++   K  + +   +F EIY+  + DLL      N K ++R +
Sbjct: 312 DTKGMIPRAVSQIFSTARELQDKGWQYKFTTSFVEIYNEMIGDLLSSNKXKNVKHEIR-M 136

Query: 360 EDGKQQVQVVGLQEREVKCVEDVLKLIDIGNSCRTSGQTSANAHS 404
                 V V  L   +V    ++ KL+   +  R    T  N  S
Sbjct: 135 AGRDNNVAVTNLTTVDVTSQHEIAKLLRQASENRAVAATKCNERS 1
>34477
          Length = 811

 Score = 55.5 bits (132), Expect = 7e-08,   Method: Compositional matrix adjust.
 Identities = 35/103 (33%), Positives = 50/103 (48%)
 Frame = +3

Query: 423 GKFSLIDLAGNERGADTSSADRQTRLEGAEINKSLLALKECIRALGRNKPHTPFRASKLT 482
           GK  L+DLAG+ER A T +  ++ + E  +IN SL  L   I   G  + HT        
Sbjct: 195 GKLHLVDLAGSERQAKTGATGQRLK-EATKINLSLSTLGNVISVPGGRQEHTHPLQELQA 371

Query: 483 QVLRDSFIGENSRTCMIATISPGMASCENTLNTLRYANRVKEF 525
                   G   +T M+A + P   + + T++TLRYANR K  
Sbjct: 372 HSPAAGLPGRQLQTVMVANMGPADYNYDETISTLRYANRAKNI 500

 Score = 42.7 bits (99), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 42/138 (30%), Positives = 64/138 (46%), Gaps = 8/138 (5%)
 Frame = +1

Query: 366 VQVVGLQEREVKCVEDVLKLIDIGNSCRTSGQTSANAHSSRSHAVFQIILRRKGKLHGKF 425
           V V  L    V   +D+ +++ +GN  R+ G T+ N HSSRSHA+F + +    K     
Sbjct: 1   VYVKDLSAFVVNNADDMDRIMTLGNKNRSVGSTNMNMHSSRSHAIFTVTVECSEKGATGS 180

Query: 426 SLIDLAGNERGADTSSADRQTRLEGAEI------NKSLLALKEC-IRALGRNKP-HTPFR 477
           S+   A           D+  +   A        +  L  L     R+L   K  H P+R
Sbjct: 181 SMYVWANCTWWTWXGQRDKPRQEPQASA*RKRPRSTCLCQLWAM*YRSLVDGKSTHIPYR 360

Query: 478 ASKLTQVLRDSFIGENSR 495
            SKLT++L+DS +G NS+
Sbjct: 361 NSKLTRLLQDS-LGGNSK 411
>17748
          Length = 621

 Score = 53.9 bits (128), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 45/146 (30%), Positives = 78/146 (53%), Gaps = 6/146 (4%)
 Frame = -3

Query: 255 SAPNEMVYRFTARPLVETIFERGMATCFAYGQTGSGKTHTMGGDF--SGKNQDCSKGIYA 312
           S  N+M  R   +     +F+   AT  AYGQTGSGKT +MGG +  S K  + + GI  
Sbjct: 430 STTNKMCTRSQHKL**PALFKGYNATVLAYGQTGSGKTFSMGGCYEASLKLDEEAMGIIP 251

Query: 313 LAARDVFLMLK-KPNYKKLELQVYATFFEIYSGKVFDL---LNRKTKLRVLEDGKQQVQV 368
              +D+F  ++ +P++     +V  ++ EIY+ ++ BL   L+++  L + E+   ++++
Sbjct: 250 RIIKDLFNGIQERPDHT---FKVTVSYLEIYNEELLBLLCPLSQRQPLTIREELNGEIKI 80

Query: 369 VGLQEREVKCVEDVLKLIDIGNSCRT 394
            GL+E  V  V+D L  +  G   RT
Sbjct: 79  KGLKEVTVGSVDDTLDCLSQGAQLRT 2
>36593
          Length = 466

 Score = 38.5 bits (88), Expect = 0.008,   Method: Composition-based stats.
 Identities = 20/48 (41%), Positives = 31/48 (64%)
 Frame = +1

Query: 480 KLTQVLRDSFIGENSRTCMIATISPGMASCENTLNTLRYANRVKEFGI 527
           KLT +L++S +G NS+T M   +SP   +   TLN+LR+A +V +  I
Sbjct: 1   KLTYLLQNS-LGGNSKTLMFVNVSPKEENFSETLNSLRFATKVNQCNI 141
>18684
          Length = 547

 Score = 36.6 bits (83), Expect = 0.039,   Method: Compositional matrix adjust.
 Identities = 17/34 (50%), Positives = 25/34 (73%)
 Frame = -2

Query: 679 QKIDILTELRDKVKSFRAALQEEEQASKQINPKR 712
           QKI  L+ L++KV++FR  +QEEE  S+ I PK+
Sbjct: 543 QKIQALSALKEKVQNFRKEMQEEETLSRNIKPKQ 442
>03912
          Length = 1719

 Score = 35.4 bits (80), Expect = 0.082,   Method: Compositional matrix adjust.
 Identities = 16/29 (55%), Positives = 22/29 (75%), Gaps = 1/29 (3%)
 Frame = -1

Query: 196 ICVCVRKRPLNKKETQMKDLDVI-TIPSK 223
           +CVC+   PL  KETQ+K LD++ TIP+K
Sbjct: 912 VCVCMYMSPLE*KETQLKTLDILFTIPTK 826
>38061
          Length = 206

 Score = 33.1 bits (74), Expect = 0.44,   Method: Compositional matrix adjust.
 Identities = 13/28 (46%), Positives = 21/28 (75%)
 Frame = -3

Query: 498 MIATISPGMASCENTLNTLRYANRVKEF 525
           ++A +SP  ++ E TLNTLRYA+R ++ 
Sbjct: 84  LVACVSPADSNMEETLNTLRYADRARKI 1
>10615
          Length = 1795

 Score = 29.6 bits (65), Expect = 4.6,   Method: Compositional matrix adjust.
 Identities = 23/73 (31%), Positives = 35/73 (47%), Gaps = 11/73 (15%)
 Frame = -3

Query: 395  SGQTSANAHSSR-------SHAVFQIILRR-KGKLHGKFSLIDLAGNERGADTSSAD--- 443
            SGQ ++ +HSS         H    ++L    G +HG   L  LAG    A + S D   
Sbjct: 1064 SGQHTSTSHSSEDVGSSSLHHGHEALVLNDLHGAVHGSLVLDGLAGGHHHASSDSVDGVR 885

Query: 444  RQTRLEGAEINKS 456
            +QTR +G  I+++
Sbjct: 884  QQTRGDGHSISQA 846
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|21450111|ref|NP_659121.1| echinoderm microtubule
associated protein like 3 [Mus musculus]
         (897 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

18461                                                                 119   6e-27
27525                                                                  76   5e-14
15780                                                                  47   4e-05
12574                                                                  41   0.002
19949                                                                  41   0.002
13335                                                                  40   0.005
12806                                                                  39   0.011
00561                                                                  37   0.026
15972                                                                  37   0.030
30295                                                                  37   0.048
19498                                                                  35   0.12 
31384                                                                  35   0.12 
27270                                                                  35   0.12 
03387                                                                  35   0.19 
29912                                                                  35   0.20 
01249                                                                  34   0.24 
14500                                                                  34   0.25 
19863                                                                  34   0.29 
28151                                                                  34   0.29 
02147                                                                  33   0.40 
00825                                                                  33   0.45 
17598                                                                  33   0.47 
10264                                                                  33   0.51 
13278                                                                  33   0.52 
01598                                                                  33   0.68 
25930                                                                  32   0.88 
34005                                                                  32   1.0  
37180                                                                  32   1.1  
14105                                                                  32   1.5  
20662                                                                  31   1.7  
04524                                                                  31   1.9  
21105                                                                  31   2.2  
15337                                                                  31   2.2  
31474                                                                  31   2.3  
02090                                                                  31   2.5  
11493                                                                  30   3.5  
02960                                                                  30   4.4  
31054                                                                  29   6.7  
27681                                                                  29   7.0  
30108                                                                  29   7.7  
06172                                                                  29   9.7  
>18461
          Length = 456

 Score =  119 bits (297), Expect = 6e-27,   Method: Compositional matrix adjust.
 Identities = 63/148 (42%), Positives = 91/148 (61%), Gaps = 1/148 (0%)
 Frame = +1

Query: 654 VVVGLNTGRWLVLDTETREIVSDVTDGNEQLSVVRYSPD-GLYLAIGSHDNMIYIYSVSS 712
           + VGL  G ++VL++ET E ++      E++S +++SPD G YLA+ SHDN + +YSV+ 
Sbjct: 7   LAVGLKDGSFVVLNSETLEEIAGFHHRKEEISDIKFSPDVGKYLAVASHDNFVDLYSVA- 183

Query: 713 CGTKSSRFGRCMGHSSFITHLDWSKDGNFIMSNSGDYEILYWDVAGGCKLLRNRYESRDR 772
            G K  R G C G SS+ITH+DW   G  +M NSG  E L+++   G ++     E    
Sbjct: 184 -GVK--RVGTCKGASSYITHIDWDTRGKVLMVNSGAKEQLFFEAPRGKRITLRNTEIEKF 354

Query: 773 EWATYTCVLGFHVYGVWPDGSDGTDINS 800
            WA++TCVLG    GVWP  SD TD+N+
Sbjct: 355 NWASWTCVLGVTCEGVWPAKSDVTDVNA 438
>27525
          Length = 828

 Score = 76.3 bits (186), Expect = 5e-14,   Method: Compositional matrix adjust.
 Identities = 43/137 (31%), Positives = 75/137 (54%), Gaps = 2/137 (1%)
 Frame = +2

Query: 667 DTETREIVSDVTDGNEQLSVVRYSPDGLYLAIGSHDNMIYIYSVSSCGTKSSRFGRCMGH 726
           D + RE  +    G  Q++ + +SPDG  LA+G HD  +++Y V   G    +    + +
Sbjct: 26  DMDGREPRNSFQVGQAQINAISFSPDGSQLAVGCHDGFVHVYVVHEDGLVFRQKSAALRY 205

Query: 727 -SSFITHLDWSKDGNFIMSNSGDYEILYWDVAGGCKLLRNRYESRDREWATYTCVLGF-H 784
            S+FI HLDWS D  ++    GDYE+++W+V    K  ++    RD  W+T++  +G+  
Sbjct: 206 NSTFIMHLDWSSDCRYLQCTLGDYELVFWEVQNMKK--QSGRALRDVNWSTFSSPVGYPP 379

Query: 785 VYGVWPDGSDGTDINSL 801
            + +  DG+ G+D + L
Sbjct: 380 CWALADDGARGSDQHGL 430

 Score = 44.7 bits (104), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 24/92 (26%), Positives = 43/92 (46%)
 Frame = +3

Query: 780 VLGFHVYGVWPDGSDGTDINSLCRSHNERVVAVADDFCKVHLFQYPCARAKAPSRMYSGH 839
           +L   + G W     G  IN  CRS     +   D   ++ LF+YP   +K   +    +
Sbjct: 363 LLDTPLVGPWQMMERGEVINMACRSKYLDFILTGDSRGRIRLFKYPSTGSKVECQETKPY 542

Query: 840 GSHVTSVRFTHDDSYLVSLGGKDASIFQWRVL 871
            S+ T+     DDS ++  GG+DA++  + ++
Sbjct: 543 SSNTTAAEILSDDSGILVSGGRDAALMYFALV 638
>15780
          Length = 735

 Score = 47.0 bits (110), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 34/92 (36%), Positives = 42/92 (45%)
 Frame = -1

Query: 506 TIVAQAHAHEGSIFALCLRRDGTVLSGGGRDRRLVQWGPGLVALQEAEIPEHFGAVRAIA 565
           T VA   AH  +++ALC  RDGTVL+ GG D  +  W   L  + E + PE         
Sbjct: 675 TAVAHLTAHTDTVYALCFSRDGTVLASGGMDNSIRLW--DLARVMEEQDPE-------TD 523

Query: 566 EGLGSELLVGTTKNALLRGDLAQGFSPVIQGH 597
             + S L V T   ALL G      SPV   H
Sbjct: 522 SNVPSSLSVNTNP-ALLLGTYYTKSSPVFGLH 430
>12574
          Length = 521

 Score = 41.2 bits (95), Expect = 0.002,   Method: Composition-based stats.
 Identities = 24/77 (31%), Positives = 40/77 (51%), Gaps = 1/77 (1%)
 Frame = +3

Query: 684 LSVVRYSPDGLYLAIGSHDNMIYIYSVSSCGTKSSRFGRCM-GHSSFITHLDWSKDGNFI 742
           LS V++SP+G +LA  S D +I I+     G    +F + + GH   ++ + WS D   +
Sbjct: 195 LSAVKFSPNGDWLASSSADKLIKIW-----GAYDGKFEKTIAGHKLGLSDVAWSSDSKLL 359

Query: 743 MSNSGDYEILYWDVAGG 759
            S S D  +  W+ + G
Sbjct: 360 CSASDDKTLKIWEFSTG 410
>19949
          Length = 903

 Score = 40.8 bits (94), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 33/134 (24%), Positives = 56/134 (41%)
 Frame = +2

Query: 302 YRGHTDCVRCLAVHPDGVRVASGQTAGVDKDGKPLQPVVHIWDSETLLKLQEIGLGAFER 361
           Y+GHT CV CL   PDG  +AS    G          +V +WD      L ++ L     
Sbjct: 107 YKGHTGCVCCLRFSPDGRWIASASEDG----------LVKLWDLTAGKLLTDLKL--HRD 250

Query: 362 GVGALAFSAADQGAFLCVVDDSNEHMLSVWDCSRGVKLAEIKSTNDSVLAVGFSPRDSSC 421
            V  + F   +   FL +   S +  +  WD      ++  +   +S+ ++ F P D  C
Sbjct: 251 AVNTIEFHPHE---FL-LASGSADRTVKFWDLETFQLISTTEPEANSIRSILFHP-DGVC 415

Query: 422 IVTSGKSHVHFWNW 435
           + +  K  +  ++W
Sbjct: 416 LYSGSKDTLKVYHW 457

 Score = 33.1 bits (74), Expect = 0.52,   Method: Compositional matrix adjust.
 Identities = 26/83 (31%), Positives = 38/83 (45%)
 Frame = +2

Query: 689 YSPDGLYLAIGSHDNMIYIYSVSSCGTKSSRFGRCMGHSSFITHLDWSKDGNFIMSNSGD 748
           + P G Y A GS D  + ++ +   G          GH+  +  L +S DG +I S S D
Sbjct: 17  FHPYGAYTASGSMDCNVKLWDIRRKGC----IYTYKGHTGCVCCLRFSPDGRWIASASED 184

Query: 749 YEILYWDVAGGCKLLRNRYESRD 771
             +  WD+  G KLL +    RD
Sbjct: 185 GLVKLWDLTAG-KLLTDLKLHRD 250
>13335
          Length = 863

 Score = 39.7 bits (91), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 28/110 (25%), Positives = 57/110 (51%), Gaps = 2/110 (1%)
 Frame = +1

Query: 664 LVLDTETREIVSDVTDGNEQ-LSVVRYSPDGLYLAIGSHDNMIYIYSVSSCGTKSSRFGR 722
           +V D +T  I  +    ++  + V ++SP   +L  GS D+ I ++ V++     S    
Sbjct: 7   IVWDVKTGSIKGEYQHASKSSIRVCKFSPSSSHLVSGSDDDTICMWEVATQKLVRSY--- 177

Query: 723 CMGHSSFITHLDWSKDGNFIMSNSGDYEILYWDVA-GGCKLLRNRYESRD 771
            +GH   +  L +S +G++++S S + ++  WD + G C+ L  R ++ D
Sbjct: 178 -VGHEDSVMALAYSPNGHYLVSGSPNGDLYVWDASFGHCRHLTLRVDAHD 324

 Score = 36.2 bits (82), Expect = 0.065,   Method: Compositional matrix adjust.
 Identities = 40/176 (22%), Positives = 65/176 (36%), Gaps = 20/176 (11%)
 Frame = +1

Query: 608 PSQNRFLTCGHDRQLCLWDGEGHALAWSMDLKETGLCA-DFHPSGAVVVVGLNTGRWLVL 666
           PS +  ++   D  +C+W+     L  S    E  + A  + P+G  +V G   G   V 
Sbjct: 91  PSSSHLVSGSDDDTICMWEVATQKLVRSYVGHEDSVMALAYSPNGHYLVSGSPNGDLYVW 270

Query: 667 DT---ETREIVSDVTDGNEQLSVVRYSPD------------GLYLAIGSHDNMIYIYSVS 711
           D      R +   V   +  ++   +SP              L LA G  DN+I +++ S
Sbjct: 271 DASFGHCRHLTLRVDAHDLGVTCCEFSPTFGTACAENSSTCNLLLATGGKDNLIKLWTFS 450

Query: 712 SCGTKSSRFGRCM----GHSSFITHLDWSKDGNFIMSNSGDYEILYWDVAGGCKLL 763
           +         +C     GHS  +    +S     + S S D  +  WD   G  L 
Sbjct: 451 AQVGSPEVTLQCRDILSGHSDLVMACAFSPSSALLASGSFDKSVRLWDSVKGVALF 618

 Score = 33.9 bits (76), Expect = 0.29,   Method: Compositional matrix adjust.
 Identities = 50/218 (22%), Positives = 82/218 (37%), Gaps = 19/218 (8%)
 Frame = +1

Query: 300 RHYRGHTDCVRCLAVHPDGVRVASGQTAGVDKDGKPLQPVVHIWDSET-LLKLQEIGLGA 358
           R Y GH D V  LA  P+G  + SG   G           +++WD+     +   + + A
Sbjct: 169 RSYVGHEDSVMALAYSPNGHYLVSGSPNG----------DLYVWDASFGHCRHLTLRVDA 318

Query: 359 FERGVGALAFS-----AADQGAFLC---VVDDSNEHMLSVWDCSRGVKLAEI-------- 402
            + GV    FS     A  + +  C   +     ++++ +W  S  V   E+        
Sbjct: 319 HDLGVTCCEFSPTFGTACAENSSTCNLLLATGGKDNLIKLWTFSAQVGSPEVTLQCRDIL 498

Query: 403 KSTNDSVLAVGFSPRDSSCIVTSGK--SHVHFWNWSGGTGAPGNGLLARKQGVFGKYKKP 460
              +D V+A  FSP  SS ++ SG     V  W+        G  L + +          
Sbjct: 499 SGHSDLVMACAFSP--SSALLASGSFDKSVRLWD-----SVKGVALFSIEAC------HS 639

Query: 461 KFIPCFVFLPDGDILTGDSEGNILTWGRSVSDSKTPGR 498
           +F+ C  F  DG +L   S   I+   +    S   G+
Sbjct: 640 RFVTCCAFSIDGTLLASGSMDRIIKIWKLTDTSSIMGK 753
>12806
          Length = 961

 Score = 38.5 bits (88), Expect = 0.011,   Method: Compositional matrix adjust.
 Identities = 48/203 (23%), Positives = 79/203 (38%), Gaps = 27/203 (13%)
 Frame = +3

Query: 695 YLAIGSHDNMIYIYSV--SSCGTKSSRFG----RCMGHSSFITHLDWSKDGNFIMSNSGD 748
           +L  G  DN I ++ +     G +   +G       GHS FI+ L  S D  F +S+S D
Sbjct: 51  FLISGGRDNNIIVWDL*PKKDGDEDQTWGVPRKTLTGHSHFISDLALSADSRFALSSSWD 230

Query: 749 YEILYWDVAGGCKLLRNRYESRDREWATYT------------------CVLGFHVYGVWP 790
             +  WD+  G    R    +RD     ++                   ++G   Y V  
Sbjct: 231 ATLRLWDIKKGSTTSRFINHTRDVLTVAFSPDNRQIASGGRDKNLKIWNIMGECKYTV-- 404

Query: 791 DGSDGTDINSLCRSHNER---VVAVADDFCKVHLFQYPCARAKAPSRMYSGHGSHVTSVR 847
           D +  TD  +  R H +    +V  A +   + ++       K     + GH + +T++ 
Sbjct: 405 DANAHTDWVTCVRFHQDTKNPIVVSASNDKTIKVWDNHTMTLK---NTFVGHKAQITALD 575

Query: 848 FTHDDSYLVSLGGKDASIFQWRV 870
            + +  YLVS G KD     W V
Sbjct: 576 MSTN--YLVS-GSKDGIAMTWNV 635

 Score = 31.2 bits (69), Expect = 1.9,   Method: Compositional matrix adjust.
 Identities = 42/200 (21%), Positives = 80/200 (40%), Gaps = 18/200 (9%)
 Frame = +3

Query: 530 LSGGGRDRRLVQWGPGLVALQEAEIPEHFGAVRA-----------IAEGLGSELLVGTTK 578
           L  GGRD  ++ W   L   ++ +  + +G  R            +A    S   + ++ 
Sbjct: 54  LISGGRDNNIIVWD--L*PKKDGDEDQTWGVPRKTLTGHSHFISDLALSADSRFALSSSW 227

Query: 579 NALLR-GDLAQGFSPV-IQGHTDELWGLCTHPSQNRFLTCGHDRQLCLWDGEGHALAWSM 636
           +A LR  D+ +G +      HT ++  +   P   +  + G D+ L +W+  G    +++
Sbjct: 228 DATLRLWDIKKGSTTSRFINHTRDVLTVAFSPDNRQIASGGRDKNLKIWNIMGEC-KYTV 404

Query: 637 DLK---ETGLCADFH--PSGAVVVVGLNTGRWLVLDTETREIVSDVTDGNEQLSVVRYSP 691
           D     +   C  FH      +VV   N     V D  T  + +       Q++ +  S 
Sbjct: 405 DANAHTDWVTCVRFHQDTKNPIVVSASNDKTIKVWDNHTMTLKNTFVGHKAQITALDMST 584

Query: 692 DGLYLAIGSHDNMIYIYSVS 711
           +  YL  GS D +   ++V+
Sbjct: 585 N--YLVSGSKDGIAMTWNVA 638
>00561
          Length = 1003

 Score = 37.4 bits (85), Expect = 0.026,   Method: Compositional matrix adjust.
 Identities = 26/93 (27%), Positives = 45/93 (48%), Gaps = 4/93 (4%)
 Frame = -3

Query: 683 QLSVVRYSPDGLYLAIGSHDNMIYIYSVSSCGTKSSRFG----RCMGHSSFITHLDWSKD 738
           Q++     PD +  A  S D  + ++ ++    + + +G    R  GHS FI+ +  S D
Sbjct: 998 QIATNPKDPDTIISA--SRDKTLIVWKLTR--DEDTNYGYPQKRLYGHSHFISDVVLSSD 831

Query: 739 GNFIMSNSGDYEILYWDVAGGCKLLRNRYESRD 771
           GN+ +S S D  +  WD+A G    R    ++D
Sbjct: 830 GNYALSGSWDQTLRLWDLAAGKTTRRFEGHTKD 732

 Score = 36.2 bits (82), Expect = 0.057,   Method: Compositional matrix adjust.
 Identities = 37/174 (21%), Positives = 63/174 (36%), Gaps = 4/174 (2%)
 Frame = -3

Query: 385 EHMLSVWDCSRGVKLAEIKSTNDSVLAVGFSPRDSSCIVTSGKSHVHFWNWSGGTGAPGN 444
           +  L +WD + G      +     VL+V FS  +   +  S    +  WN          
Sbjct: 803 DQTLRLWDLAAGKTTRRFEGHTKDVLSVAFSADNRQIVSGSRDKTIKLWN---------- 654

Query: 445 GLLARKQGVFGKYKKPKFIPCFVFLPDGDILTGDSEGNILTWGRSVSDSKTPGRGGAKET 504
             LA  +    +     ++ C  F P+       S G    W R+V   K       K  
Sbjct: 653 -TLAECKFTIQEDGHTDWVSCVRFSPNHSNPIIVSCG----WDRTV---KVWNLANCK-- 504

Query: 505 YTIVAQAHAHEGSIFALCLRRDGTVLSGGGRDRRLVQW----GPGLVALQEAEI 554
             +    H H G +  + +  DG++ + GG+D + + W    G  L  L+  +I
Sbjct: 503 --LKNNHHGHNGYLNTVTVSPDGSLCTSGGKDSKALLWDLNDGKNLYTLEHNDI 348

 Score = 33.9 bits (76), Expect = 0.29,   Method: Compositional matrix adjust.
 Identities = 22/83 (26%), Positives = 42/83 (50%), Gaps = 2/83 (2%)
 Frame = -3

Query: 682 EQLSVVRYSPDGLYLAIGS--HDNMIYIYSVSSCGTKSSRFGRCMGHSSFITHLDWSKDG 739
           + +S VR+SP+     I S   D  + ++++++C  K++  G    H+ ++  +  S DG
Sbjct: 608 DWVSCVRFSPNHSNPIIVSCGWDRTVKVWNLANCKLKNNHHG----HNGYLNTVTVSPDG 441

Query: 740 NFIMSNSGDYEILYWDVAGGCKL 762
           +   S   D + L WD+  G  L
Sbjct: 440 SLCTSGGKDSKALLWDLNDGKNL 372
>15972
          Length = 1069

 Score = 37.4 bits (85), Expect = 0.030,   Method: Compositional matrix adjust.
 Identities = 20/65 (30%), Positives = 28/65 (43%)
 Frame = +3

Query: 596 GHTDELWGLCTHPSQNRFLTCGHDRQLCLWDGEGHALAWSMDLKETGLCADFHPSGAVVV 655
           GH   +  L  HPS    LT   DR L LW+     +A+  ++KE      + P G   V
Sbjct: 231 GHKGPVRHLAVHPSGKLTLTVSQDRTLRLWNNMNGRIAFISNMKEAAESVRWAPGGLYYV 410

Query: 656 VGLNT 660
           V   +
Sbjct: 411 VAFRS 425
>30295
          Length = 593

 Score = 36.6 bits (83), Expect = 0.048,   Method: Compositional matrix adjust.
 Identities = 28/96 (29%), Positives = 48/96 (50%), Gaps = 1/96 (1%)
 Frame = +2

Query: 661 GRWLVLDTETREIVSDVTDGNEQLSVVRYSPDGLYLAIGSHDNMIYIYSVSSCGTKSSRF 720
           G+ +V D  T   V  +   +  +    Y+P G Y+A G  DN+  IYS+ +    + R 
Sbjct: 311 GKLIVWDGYTTNKVHAIPLRSSWVMTCAYAPSGGYVACGGLDNICSIYSLKT-REGNVRV 487

Query: 721 GRCM-GHSSFITHLDWSKDGNFIMSNSGDYEILYWD 755
            R + GH+ +++   +  D N I+++SGD     WD
Sbjct: 488 SRELPGHTGYLSCCRFIDD-NQIVTSSGDMTCALWD 592
>19498
          Length = 903

 Score = 35.4 bits (80), Expect = 0.12,   Method: Compositional matrix adjust.
 Identities = 23/85 (27%), Positives = 38/85 (44%), Gaps = 13/85 (15%)
 Frame = -1

Query: 684 LSVVRYSPDGLYLAIGSHDNMIYIYSVSSCGTKSSRFGRCM-------------GHSSFI 730
           ++ VR+S +G +LA G  D +I I+ +S        FG  +             GH+  +
Sbjct: 777 VNCVRWSENGKFLASGGDDKLIMIWQISRGFGSGKSFGSNVTILEHWRSVATLRGHAGDV 598

Query: 731 THLDWSKDGNFIMSNSGDYEILYWD 755
             L WS    ++ S S D  I+ W+
Sbjct: 597 LDLAWSPQDLWLASCSVDNTIVVWN 523

 Score = 35.0 bits (79), Expect = 0.13,   Method: Compositional matrix adjust.
 Identities = 24/85 (28%), Positives = 42/85 (49%), Gaps = 13/85 (15%)
 Frame = -1

Query: 673 IVSDVTDGNEQLSVVR----------YSPDGLYLAIGSHDNMIYIYSVSSCGTKS---SR 719
           +V +    +EQ++V+R          + P G YLA  S D  + ++  S    ++   S 
Sbjct: 534 VVWNALKFSEQVAVIRGHAGMVKGVTWDPVGRYLASQSDDKTLRVWRTSDWKEETCVKSC 355

Query: 720 FGRCMGHSSFITHLDWSKDGNFIMS 744
           F  C G ++ +  L+WS DGN ++S
Sbjct: 354 FKEC-GGTTHVLRLNWSPDGNHVVS 283
>31384
          Length = 474

 Score = 35.0 bits (79), Expect = 0.12,   Method: Composition-based stats.
 Identities = 21/79 (26%), Positives = 38/79 (48%), Gaps = 3/79 (3%)
 Frame = -1

Query: 681 NEQLSVVRYSPDGL---YLAIGSHDNMIYIYSVSSCGTKSSRFGRCMGHSSFITHLDWSK 737
           ++ +S +++SP  L   +L  GS DN +  + V   G    +  +   H+  +  +DWS 
Sbjct: 276 DDSVSCLKFSPGALPSTFLISGSWDNKVSCWEVQQSGQTIPKAQQT--HTGPVLDVDWSD 103

Query: 738 DGNFIMSNSGDYEILYWDV 756
           DG  + + S D     WD+
Sbjct: 102 DGTKVFTASCDKTAKVWDL 46
>27270
          Length = 1078

 Score = 35.0 bits (79), Expect = 0.12,   Method: Compositional matrix adjust.
 Identities = 21/67 (31%), Positives = 36/67 (53%)
 Frame = +2

Query: 690 SPDGLYLAIGSHDNMIYIYSVSSCGTKSSRFGRCMGHSSFITHLDWSKDGNFIMSNSGDY 749
           + D   +A+GS D  + +YSV +  T +    +  GHS  +T + W  DG  + S+S D 
Sbjct: 170 AADSAVVAVGSADGSVGLYSVET-HTYTHMLNK--GHSKAVTDMCWRADGRTLYSSSLDG 340

Query: 750 EILYWDV 756
            ++ W+V
Sbjct: 341 HVIGWNV 361
>03387
          Length = 1891

 Score = 34.7 bits (78), Expect = 0.19,   Method: Compositional matrix adjust.
 Identities = 45/183 (24%), Positives = 80/183 (43%), Gaps = 19/183 (10%)
 Frame = +1

Query: 594 IQGHTDELWGLCTHPSQN-RFLTCGHDRQLCLWD-----GEGHAL-AWSMDLKETGLCAD 646
           ++GH  E +GL  +P+ N   L+   D  +CLWD      E   + A ++    T +  D
Sbjct: 349 LKGHQKEGYGLSWNPNLNGHLLSASDDHTICLWDINSTQRESRVVDAHTIFTGHTSVVED 528

Query: 647 -----FHPS--GAVVVVGLNTGRWLVLDT--ETREIVSDVTDGN-EQLSVVRYSP-DGLY 695
                 H S  G+V     +  + ++ DT   T    S V D +  +++ + ++P     
Sbjct: 529 VAWHLLHESLFGSVA----DDQKLMIWDTRSNTTSKPSHVVDAHTAEVNCLSFNPYSEFI 696

Query: 696 LAIGSHDNMIYIYSVSSCGTKSSRFGRCMGHSSFITHLDWSKDGNFIMSNSG-DYEILYW 754
           LA GS D  + ++ + +   K   F     H   I  + WS     I+++SG D  +  W
Sbjct: 697 LATGSADKTVALWDLRNLKLKLHSFE---SHKDEIFQVQWSPHNETILASSGTDRRLHVW 867

Query: 755 DVA 757
           D++
Sbjct: 868 DLS 876
>29912
          Length = 510

 Score = 34.7 bits (78), Expect = 0.20,   Method: Compositional matrix adjust.
 Identities = 14/46 (30%), Positives = 30/46 (65%)
 Frame = +3

Query: 674 VSDVTDGNEQLSVVRYSPDGLYLAIGSHDNMIYIYSVSSCGTKSSR 719
           V  ++  ++++  +R+SPDG YLA G++DN++ ++     G  S++
Sbjct: 237 VGTLSGHSQEVCGLRWSPDGKYLASGANDNLLCVWPAQVTGGNSTQ 374

 Score = 32.3 bits (72), Expect = 0.88,   Method: Compositional matrix adjust.
 Identities = 30/112 (26%), Positives = 47/112 (41%), Gaps = 10/112 (8%)
 Frame = +3

Query: 658 LNTGRWLVLDTETREI-VSDVTDGNEQLSVVRY-------SPDGLYLAIGSHDNMIYIYS 709
           +  G +L L T T E+ V DVT   +  ++  +       S +   ++ GS    I+ + 
Sbjct: 36  IKEGNYLALGTSTGEVQVWDVTQQKKLRTMAGHAARVGSLSWNSFIVSSGSRSGNIHHHD 215

Query: 710 VSSCGTKSSRFGRCMGHSSFITHLDWSKDGNFIMSNSGDYEILYW--DVAGG 759
           V          G   GHS  +  L WS DG ++ S + D  +  W   V GG
Sbjct: 216 VR---VADHHVGTLSGHSQEVCGLRWSPDGKYLASGANDNLLCVWPAQVTGG 362
>01249
          Length = 1743

 Score = 34.3 bits (77), Expect = 0.24,   Method: Compositional matrix adjust.
 Identities = 20/49 (40%), Positives = 28/49 (57%)
 Frame = -1

Query: 299 QRHYRGHTDCVRCLAVHPDGVRVASGQTAGVDKDGKPLQPVVHIWDSET 347
           +R  +GH+D V CLA   DG R+ASG      ++GK     V IW+ E+
Sbjct: 936 ERVLQGHSDAVTCLAFSSDGQRLASGS-----QNGK-----VIIWNMES 820
>14500
          Length = 1238

 Score = 34.3 bits (77), Expect = 0.25,   Method: Compositional matrix adjust.
 Identities = 14/46 (30%), Positives = 30/46 (65%)
 Frame = +2

Query: 674 VSDVTDGNEQLSVVRYSPDGLYLAIGSHDNMIYIYSVSSCGTKSSR 719
           V  ++  ++++  +R+SPDG YLA G++DN++ ++     G  S++
Sbjct: 38  VGTLSGHSQEVCGLRWSPDGKYLASGANDNLLCVWPAQVTGGNSTQ 175
>19863
          Length = 502

 Score = 33.9 bits (76), Expect = 0.29,   Method: Composition-based stats.
 Identities = 19/65 (29%), Positives = 34/65 (52%)
 Frame = +1

Query: 692 DGLYLAIGSHDNMIYIYSVSSCGTKSSRFGRCMGHSSFITHLDWSKDGNFIMSNSGDYEI 751
           DGL L  GS D  I ++ V +   K     R  GH+ ++  + +S+D  +++S S D  +
Sbjct: 4   DGLQLVSGSSDMSIVVWDVENGVQKL----RLQGHAGWVNDVHFSQDQCWLLSCSNDNTV 171

Query: 752 LYWDV 756
             W++
Sbjct: 172 RIWNI 186
>28151
          Length = 1429

 Score = 33.9 bits (76), Expect = 0.29,   Method: Compositional matrix adjust.
 Identities = 19/64 (29%), Positives = 33/64 (51%)
 Frame = +3

Query: 649 PSGAVVVVGLNTGRWLVLDTETREIVSDVTDGNEQLSVVRYSPDGLYLAIGSHDNMIYIY 708
           P+  VV +G ++ R+  ++ E    +  V  G+   S    SP G Y+ +G +DN IY+ 
Sbjct: 42  PAKMVVFIGSHSHRFSAVNLEYGTQLWSVRLGDRVESSACLSPCGQYVIVGCYDNKIYVL 221

Query: 709 SVSS 712
             S+
Sbjct: 222 KAST 233
>02147
          Length = 1547

 Score = 33.5 bits (75), Expect = 0.40,   Method: Compositional matrix adjust.
 Identities = 25/122 (20%), Positives = 42/122 (34%), Gaps = 1/122 (0%)
 Frame = +2

Query: 593 VIQGHTDELWGLCTHPSQNRFLTCGHDRQLCLWDGEGHALAWSMDLKETGLCADFHPSGA 652
             +GH   +WG   +    R  T   D    +WD E      +   K      DF   G 
Sbjct: 158 TFEGHKGAVWGATLNREATRAATGAADFSAKIWDAEKGEELQTFSHKHIVKSVDFSHDGT 337

Query: 653 VVVVGLNTGRWLVLDTETREIVSDVTDGN-EQLSVVRYSPDGLYLAIGSHDNMIYIYSVS 711
            ++ G N     V D    +       G+   +    +  DG  +   S D  + ++S+ 
Sbjct: 338 ALLTGSNEKLLKVFDLVNTDAEPKSFAGHTSNIKGALFLSDGKRIISASDDKTVRLWSLE 517

Query: 712 SC 713
           +C
Sbjct: 518 TC 523
>00825
          Length = 1821

 Score = 33.1 bits (74), Expect = 0.45,   Method: Compositional matrix adjust.
 Identities = 32/129 (24%), Positives = 53/129 (41%), Gaps = 6/129 (4%)
 Frame = -2

Query: 588  QGFSPVIQGHTDELWGLCTHPSQNRFLTCGHDRQLCLW--DGEGHALAWSMDL---KETG 642
            Q  +  +Q H   + G+  H S   F +CG D+ +  W  D EG      ++    K   
Sbjct: 1775 QQMACRVQAHDGIVHGMAAHSSGQYFFSCGSDKTIKQWSLDPEGTIAPEPVNTLLAKCIY 1596

Query: 643  LCADFHPSGAVVVVGLNTGRWLVLDTETREIVSDVTDGNEQLSVVRYSPDGLY-LAIGSH 701
               D H    + V   +  R  V D +  E +   + G E +  V+++P   Y L   +H
Sbjct: 1595 TSLDHHWKDDIFVT--SGSRVDVWDEKRSEPMRSFSWGVESVHHVKFNPVETYLLGAAAH 1422

Query: 702  DNMIYIYSV 710
            D  I +Y +
Sbjct: 1421 DRSILLYDM 1395
>17598
          Length = 875

 Score = 33.1 bits (74), Expect = 0.47,   Method: Compositional matrix adjust.
 Identities = 20/83 (24%), Positives = 38/83 (45%), Gaps = 6/83 (7%)
 Frame = +1

Query: 695 YLAIGSHDNMIYIYSV--SSCGTKSSRFG----RCMGHSSFITHLDWSKDGNFIMSNSGD 748
           +L  G  D ++ ++ +     G +   +G       GHS F++ +  S D  +++S+S D
Sbjct: 7   FLIXGGRDKLLIVWDLVPRKDGDEDETWGGPRRTLQGHSHFVSDVSLSADSRYVLSSSWD 186

Query: 749 YEILYWDVAGGCKLLRNRYESRD 771
             +  WD+  G    R    +RD
Sbjct: 187 ATLRLWDIKKGNTTRRFISHTRD 255
>10264
          Length = 416

 Score = 33.1 bits (74), Expect = 0.51,   Method: Compositional matrix adjust.
 Identities = 21/66 (31%), Positives = 34/66 (51%)
 Frame = -1

Query: 805 HNERVVAVADDFCKVHLFQYPCARAKAPSRMYSGHGSHVTSVRFTHDDSYLVSLGGKDAS 864
           H+ R+V+V  D      F +   +  A ++ + GH   + + +F+  D  LV  GG DAS
Sbjct: 209 HDARLVSVGYD---AEAFVWDVQKGTALAQ-FKGHMGRLLTCQFSGLDPDLVMTGGSDAS 42

Query: 865 IFQWRV 870
           +  WRV
Sbjct: 41  VHVWRV 24
>13278
          Length = 870

 Score = 33.1 bits (74), Expect = 0.52,   Method: Compositional matrix adjust.
 Identities = 15/36 (41%), Positives = 23/36 (63%)
 Frame = +1

Query: 677 VTDGNEQLSVVRYSPDGLYLAIGSHDNMIYIYSVSS 712
           +T   E +  V +SPDG YLA GS D  ++I++V +
Sbjct: 190 LTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNVQT 297

 Score = 28.9 bits (63), Expect = 8.5,   Method: Compositional matrix adjust.
 Identities = 16/58 (27%), Positives = 25/58 (43%)
 Frame = +1

Query: 377 LCVVDDSNEHMLSVWDCSRGVKLAEIKSTNDSVLAVGFSPRDSSCIVTSGKSHVHFWN 434
           L +   S +  + +W+  RG+ L  +    + V +V FSP        S    VH WN
Sbjct: 115 LILASASFDSTVRLWEVERGLCLHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWN 288
>01598
          Length = 1545

 Score = 32.7 bits (73), Expect = 0.68,   Method: Compositional matrix adjust.
 Identities = 21/66 (31%), Positives = 34/66 (51%)
 Frame = +1

Query: 805  HNERVVAVADDFCKVHLFQYPCARAKAPSRMYSGHGSHVTSVRFTHDDSYLVSLGGKDAS 864
            H+ R+V+V  D      F +   +  A ++ + GH   + + +F+  D  LV  GG DAS
Sbjct: 1336 HDARLVSVGYD---AEAFVWDVQKGTALAQ-FKGHMGRLLTCQFSGLDPDLVMTGGSDAS 1503

Query: 865  IFQWRV 870
            +  WRV
Sbjct: 1504 VHVWRV 1521
>25930
          Length = 419

 Score = 32.3 bits (72), Expect = 0.88,   Method: Composition-based stats.
 Identities = 19/64 (29%), Positives = 30/64 (46%)
 Frame = +1

Query: 695 YLAIGSHDNMIYIYSVSSCGTKSSRFGRCMGHSSFITHLDWSKDGNFIMSNSGDYEILYW 754
           ++A+GS    I IY V     + +R     G    I +L+WS D   ++S S    +  W
Sbjct: 100 FVAVGSVRGDILIYDVRLEPWRLARIAPSNGQDDSIKNLNWSLDATRLISVSESGTLQVW 279

Query: 755 DVAG 758
           D+ G
Sbjct: 280 DLEG 291
>34005
          Length = 456

 Score = 32.0 bits (71), Expect = 1.0,   Method: Compositional matrix adjust.
 Identities = 19/81 (23%), Positives = 37/81 (45%), Gaps = 3/81 (3%)
 Frame = +1

Query: 682 EQLSVVRYSPDGLYLAIGSHDNMIYIYSVSSCGTKSSRFGRCMGHSSFITHLDWSKDGNF 741
           +++  + +SPD  +LA GS+DN + I+  S+ G           H + +  + W      
Sbjct: 115 QEVCGLSWSPDATFLASGSNDNSVNIWD-STLGMDVPPLHTLTSHQAAVKAVAWCPWQTR 291

Query: 742 IMSNSG---DYEILYWDVAGG 759
           +++  G   D  I +W+   G
Sbjct: 292 MLATGGGTNDRHIRFWNTNTG 354

 Score = 30.4 bits (67), Expect = 3.0,   Method: Compositional matrix adjust.
 Identities = 13/40 (32%), Positives = 20/40 (50%)
 Frame = +1

Query: 716 KSSRFGRCMGHSSFITHLDWSKDGNFIMSNSGDYEILYWD 755
           +++R+G C      +  L WS D  F+ S S D  +  WD
Sbjct: 79  RATRWGFCPLTPQEVCGLSWSPDATFLASGSNDNSVNIWD 198
>37180
          Length = 681

 Score = 32.0 bits (71), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 15/40 (37%), Positives = 19/40 (47%)
 Frame = +1

Query: 593 VIQGHTDELWGLCTHPSQNRFLTCGHDRQLCLWDGEGHAL 632
           V+ GH  EL  +  HP+Q   +T   D    LWD    AL
Sbjct: 4   VLNGHDQELSDVHAHPTQRLVVTSSKDMTFRLWDFRDSAL 123
>14105
          Length = 429

 Score = 31.6 bits (70), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 17/45 (37%), Positives = 25/45 (55%)
 Frame = +3

Query: 667 DTETREIVSDVTDGNEQLSVVRYSPDGLYLAIGSHDNMIYIYSVS 711
           DTE     S V DG   L+ V ++P GL++ IG     +Y+Y V+
Sbjct: 150 DTEV-PTASIVVDGAPALNRVSWTPSGLHVTIGDESGKLYVYDVA 281
>20662
          Length = 1220

 Score = 31.2 bits (69), Expect = 1.7,   Method: Compositional matrix adjust.
 Identities = 12/33 (36%), Positives = 21/33 (63%), Gaps = 1/33 (3%)
 Frame = +2

Query: 595 QGHTDELWGLCTHPSQNR-FLTCGHDRQLCLWD 626
           + H+D +W +  HP++   FL+C  D ++ LWD
Sbjct: 500 RAHSDIVWDVQCHPTEPALFLSCSQDGKIVLWD 598
>04524
          Length = 1340

 Score = 31.2 bits (69), Expect = 1.9,   Method: Compositional matrix adjust.
 Identities = 11/36 (30%), Positives = 22/36 (61%)
 Frame = -1

Query: 723 CMGHSSFITHLDWSKDGNFIMSNSGDYEILYWDVAG 758
           C+GH+ F+  L + ++   ++S SGD  +  W++ G
Sbjct: 911 CLGHTQFVNCLVYVEEFRVLISGSGDCTVRAWNMEG 804
>21105
          Length = 650

 Score = 31.2 bits (69), Expect = 2.2,   Method: Composition-based stats.
 Identities = 15/65 (23%), Positives = 31/65 (47%)
 Frame = +1

Query: 648 HPSGAVVVVGLNTGRWLVLDTETREIVSDVTDGNEQLSVVRYSPDGLYLAIGSHDNMIYI 707
           HP+  + +           D  T +++  +    + ++ +   P+GLYL  GSHD  I +
Sbjct: 91  HPTMPITITAHEDRHIRFFDNNTGKLIHAMVAHLDSVTSLAVDPNGLYLLSGSHDCSIRL 270

Query: 708 YSVSS 712
           +++ S
Sbjct: 271 WNLDS 285
>15337
          Length = 860

 Score = 30.8 bits (68), Expect = 2.2,   Method: Compositional matrix adjust.
 Identities = 32/141 (22%), Positives = 53/141 (37%), Gaps = 3/141 (2%)
 Frame = -1

Query: 617 GHDRQLCLWDGEGHALAWSMDLKETGLCADFHPSGAVVVVGLNTGRWLVLDTETREIVSD 676
           G   Q  +  G G   A++ +L     C    P+      G     +      TR  +  
Sbjct: 509 GSGNQFLVSHGSGQMYAYNEELP----CGQTPPNYQPFKQGEGYSVFTCKTKSTRNPLYR 342

Query: 677 VTDGNEQLSVVRYSPDGLYLAIGSHDNMIYIYSVSS---CGTKSSRFGRCMGHSSFITHL 733
              G   +S   +SP   YLA+   D  + +++ +S    GT  S FG  +        +
Sbjct: 341 WVVGTGAISEFAFSPCSRYLAVVGQDGHLRVFNYNSMELIGTMKSYFGGLLC-------V 183

Query: 734 DWSKDGNFIMSNSGDYEILYW 754
            WS DG +I++   D  +  W
Sbjct: 182 CWSPDGKYIVTGGEDDLVTVW 120
>31474
          Length = 403

 Score = 30.8 bits (68), Expect = 2.3,   Method: Compositional matrix adjust.
 Identities = 26/95 (27%), Positives = 37/95 (38%), Gaps = 5/95 (5%)
 Frame = -3

Query: 670 TREIVSDVTDGNEQLSVVRYSPDGLYLAIGSHDNMIYIYSVSSCGTKSSRFGRCM----- 724
           T E V  ++  +E    V ++P G  LA    D +I I+       K      C      
Sbjct: 338 TLEEVCCLSAHDEHAWCVAWNPTGTLLASCGSDKIIKIWG------KEGDNWVCKSTLTD 177

Query: 725 GHSSFITHLDWSKDGNFIMSNSGDYEILYWDVAGG 759
            H+  +  L WS  GN++ S S D     W   GG
Sbjct: 176 AHTRTVRSLGWSPCGNYLSSASFDATTAVWSRKGG 72
>02090
          Length = 1841

 Score = 30.8 bits (68), Expect = 2.5,   Method: Compositional matrix adjust.
 Identities = 17/54 (31%), Positives = 27/54 (50%)
 Frame = -3

Query: 300  RHYRGHTDCVRCLAVHPDGVRVASGQTAGVDKDGKPLQPVVHIWDSETLLKLQE 353
            R ++GHTD   C+ + PDG ++ +G   G+D         V  WD     +LQ+
Sbjct: 1518 RQFQGHTDGASCIDISPDGTKLWTG---GLDN-------TVRSWDLREGRQLQQ 1387

 Score = 29.6 bits (65), Expect = 5.3,   Method: Compositional matrix adjust.
 Identities = 46/206 (22%), Positives = 81/206 (39%), Gaps = 1/206 (0%)
 Frame = -3

Query: 666  LDTETREIVSDVTDGNEQLSVVRYSPDGLYLAIGSHDNMIYIYSVSSCGTKSSRFGRCMG 725
            L T T  I +++T        +  SPDG        D  I ++ + +  T   +F    G
Sbjct: 1671 LATPTPRIKAELTSSAPACYALAISPDGKVCFSCCSDGNIAVWDLHN-QTLVRQF---QG 1504

Query: 726  HSSFITHLDWSKDGNFIMSNSGDYEILYWDVAGGCKLLRNRYESRDREWATYTCVLGFHV 785
            H+   + +D S DG  + +   D  +  WD+  G +L ++ + S+          LG+  
Sbjct: 1503 HTDGASCIDISPDGTKLWTGGLDNTVRSWDLREGRQLQQHDFSSQ-------IFSLGYCP 1345

Query: 786  YGVW-PDGSDGTDINSLCRSHNERVVAVADDFCKVHLFQYPCARAKAPSRMYSGHGSHVT 844
             G W   G + +++  L  S  ++         ++HL                 H S V 
Sbjct: 1344 TGEWLAVGMESSNVEVLHHSKPDKY--------QLHL-----------------HESCVL 1240

Query: 845  SVRFTHDDSYLVSLGGKDASIFQWRV 870
            S++F +   + VS  GKD  +  WR 
Sbjct: 1239 SLKFAYCGKWFVST-GKDNLLNAWRT 1165
>11493
          Length = 535

 Score = 30.4 bits (67), Expect = 3.5,   Method: Compositional matrix adjust.
 Identities = 11/25 (44%), Positives = 17/25 (68%)
 Frame = -2

Query: 300 RHYRGHTDCVRCLAVHPDGVRVASG 324
           R ++GHTD   C+ + PDG R+ +G
Sbjct: 99  RQFQGHTDGASCIDISPDGSRLWTG 25
>02960
          Length = 1577

 Score = 30.0 bits (66), Expect = 4.4,   Method: Compositional matrix adjust.
 Identities = 35/145 (24%), Positives = 55/145 (37%), Gaps = 15/145 (10%)
 Frame = +2

Query: 303 RGHTDCVRCLAVHPDGVRVASGQ--------TAGVDKDGKPLQPVVHIWDSETLLKLQEI 354
           RGH   V C+AV PD  ++ +G         +   + DG   +      D+E   K ++ 
Sbjct: 746 RGHAASVDCVAVSPDSQQMCTGSWDKMLKLWSTDCNVDGDQSE------DTERPSKKKKS 907

Query: 355 GLGAFERGVGALAFSAADQGAFLC-------VVDDSNEHMLSVWDCSRGVKLAEIKSTND 407
                +  V  L  S   +            VV  S +H L +WD     + + I+ +  
Sbjct: 908 AKSTTQTRVPVLTLSGHAEAVSAVRWLDPHRVVTSSWDHSLRLWDLHTAQQTSLIQGSK- 1084

Query: 408 SVLAVGFSPRDSSCIVTSGKSHVHF 432
           +VL V +SP     I  S   HV  
Sbjct: 1085AVLDVAYSPLSHMLITGSADRHVRL 1159
>31054
          Length = 392

 Score = 29.3 bits (64), Expect = 6.7,   Method: Compositional matrix adjust.
 Identities = 26/100 (26%), Positives = 42/100 (42%)
 Frame = -2

Query: 300 RHYRGHTDCVRCLAVHPDGVRVASGQTAGVDKDGKPLQPVVHIWDSETLLKLQEIGLGAF 359
           ++  GH   +  LAV+ DGV V SG   G           +H+WD  T    Q I     
Sbjct: 307 QNLSGHNAIINTLAVNSDGVLV-SGADNG----------TMHLWDWRTGYNFQRIHAAV- 164

Query: 360 ERGVGALAFSAADQGAFLCVVDDSNEHMLSVWDCSRGVKL 399
               G+L    ++ G F C  D S   +++  +  + +K+
Sbjct: 163 --QPGSL---DSESGFFACTFDQSESRLITA-EADKTIKV 62
>27681
          Length = 465

 Score = 29.3 bits (64), Expect = 7.0,   Method: Composition-based stats.
 Identities = 12/30 (40%), Positives = 17/30 (56%)
 Frame = +3

Query: 730 ITHLDWSKDGNFIMSNSGDYEILYWDVAGG 759
           I  L W+K GN+I+S   D   + WD + G
Sbjct: 294 IFALKWNKRGNYILSAGVDKTTIIWDASSG 383
>30108
          Length = 1032

 Score = 29.3 bits (64), Expect = 7.7,   Method: Compositional matrix adjust.
 Identities = 24/75 (32%), Positives = 33/75 (44%), Gaps = 4/75 (5%)
 Frame = +1

Query: 694 LYLAIGSHDNMIYIYSVSSCGTKSSRFGRCMGHSSF--ITHLDWSKDGNFIMSNSG-DYE 750
           L +A  S   + +I   S     SS   + + HS    ITHL W    N ++S S  D  
Sbjct: 274 LAVACQSAVLIWHIEPTSLAARPSSSSVQVLQHSGHCPITHLAWLPSANILLSASPVDTA 453

Query: 751 ILYWDVAG-GCKLLR 764
           ++ W V G  C  LR
Sbjct: 454 VMAWSVGGEACTALR 498
>06172
          Length = 2175

 Score = 28.9 bits (63), Expect = 9.7,   Method: Compositional matrix adjust.
 Identities = 24/77 (31%), Positives = 33/77 (42%)
 Frame = +2

Query: 348 LLKLQEIGLGAFERGVGALAFSAADQGAFLCVVDDSNEHMLSVWDCSRGVKLAEIKSTND 407
             KL   G     +GV A  FS  D   F  + +D N   +  W   R  KLA    T +
Sbjct: 740 FWKLSAPGTDKIWKGVWAQIFSYTD---FKTMANDLNG--VCTWHFQRQAKLAWDNRTIE 904

Query: 408 SVLAVGFSPRDSSCIVT 424
            +L +G +   S+C VT
Sbjct: 905 RMLLIGSNSXVSACTVT 955
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6753138|ref|NP_033851.1| Na+/K+ -ATPase beta 1
subunit [Mus musculus]
         (304 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

06574                                                                 117   6e-27
13469                                                                  40   0.001
04206                                                                  28   5.7  
>06574
          Length = 2012

 Score =  117 bits (293), Expect = 6e-27,   Method: Compositional matrix adjust.
 Identities = 83/303 (27%), Positives = 140/303 (46%), Gaps = 19/303 (6%)
 Frame = -3

Query: 11   SWKKFIWNSEKKEFLGRTGGSWFKILLFYVIFYGCLAGIFIGTIQVMLLTISELKPTYQD 70
            S+  F+WNSE+K  LGR G SW +I  FY+I+Y CLAG F+G + +   T+ E +P    
Sbjct: 1848 SFCTFLWNSEEKTVLGRGGRSWAEIGFFYLIYYICLAGFFVGMLAIFYQTVDEKRPKLTG 1669

Query: 71   RVA----PPGL--TQIPQIQKTEISFRPNDPKSYEAYVLNIIRFLEKYKDSAQKDDMIFE 124
              +     PG+    IP ++ T + FR  DP SY+ +V +I + L+ Y D+   +D   +
Sbjct: 1668 ESSLLKGNPGMGFQPIPDVEYTLVRFR-RDPDSYKPHVKSISKILQPYLDAEVAEDKKGK 1492

Query: 125  DCG--NVPSEPKERGDINHERGERKVCRFKLDWLGNCSGLNDDSYGYRE-----GKPCII 177
             C   ++P             GE + CR  +  L     + D+ +GY E     G+PC++
Sbjct: 1491 VCSATDLP-------------GEGEACRVDVASLTQSCNI-DNKFGYNETSTLSGQPCVL 1354

Query: 178  IKLNRVLGFKPKPPKNESL------ETYPLMMKYNPNVLPVQCTGKRDEDKDKVGNIEYF 231
            ++LN++  + P+    E++      E     +  +P ++ + C G+   D+D +G I+Y+
Sbjct: 1353 LRLNKIFDWMPEKYTKENIKNSGASEELQQKILDDPEMIYIDCVGENPADRDNIGPIQYY 1174

Query: 232  GMXXXXXXXXXXXXXXXXXXXXXXXXXXXAVQFTNLTVDTEIRVECKAYGENIGYSEKDR 291
                                          VQFT    +  + VEC+A   NI Y   ++
Sbjct: 1173 ------PEQGFRHYYYPFTNQPDYMSPLVFVQFTKPAENVALMVECRALAPNINYDRTEK 1012

Query: 292  FQG 294
              G
Sbjct: 1011 EGG 1003
>13469
          Length = 521

 Score = 40.0 bits (92), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 29/103 (28%), Positives = 52/103 (50%), Gaps = 1/103 (0%)
 Frame = -1

Query: 76  GLTQIPQIQKTEISFRPNDPKSYEAYVLNIIRFLEKYKDSAQKDDMIFEDCGNVPSEPKE 135
           G    P I  T + F   D  +Y  ++ +I  +L+ Y++  Q+ +  + DC  +    + 
Sbjct: 278 GFRPQPNIHNTIVRFVKGDGATYVHHLDHIEAYLKYYENQNQQGEN-YIDCNEI--RERR 108

Query: 136 RGDINHERGERKVCRFKLDWLG-NCSGLNDDSYGYREGKPCII 177
             D+N      KVCRF L  LG +C  +   ++G+ +G+PCI+
Sbjct: 107 TSDLN------KVCRFDLINLGPDC--VKQQNFGFDDGQPCIL 3
>04206
          Length = 778

 Score = 27.7 bits (60), Expect = 5.7,   Method: Compositional matrix adjust.
 Identities = 15/51 (29%), Positives = 27/51 (52%)
 Frame = +1

Query: 131 SEPKERGDINHERGERKVCRFKLDWLGNCSGLNDDSYGYREGKPCIIIKLN 181
           SEP +  D +HE  E+ V      +   CS L  + +   +G+PC I++++
Sbjct: 79  SEPIKMAD-DHEDFEQTVSGASETYPRQCSALRKNEFVVIKGRPCKIVEMS 228
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|46275816|ref|NP_996893.1| MAM domain containing
glycosylphosphatidylinositol anchor 2 [Mus musculus]
         (949 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

36495                                                                 119   7e-27
19336                                                                  90   4e-18
13135                                                                  59   8e-09
09987                                                                  57   5e-08
20110                                                                  53   6e-07
27666                                                                  51   2e-06
29990                                                                  46   1e-05
18345                                                                  47   3e-05
06028                                                                  46   7e-05
19356                                                                  46   8e-05
34811                                                                  42   8e-04
08294                                                                  42   0.001
29932                                                                  40   0.004
06343                                                                  39   0.008
17530                                                                  37   0.029
25766                                                                  35   0.082
11855                                                                  36   0.082
38127                                                                  35   0.14 
29881                                                                  34   0.29 
36498                                                                  34   0.36 
37675                                                                  32   1.6  
32888                                                                  31   1.7  
12764                                                                  31   1.9  
35419                                                                  30   5.5  
18575                                                                  29   8.7  
07294                                                                  29   9.0  
>36495
          Length = 718

 Score =  119 bits (297), Expect = 7e-27,   Method: Composition-based stats.
 Identities = 70/178 (39%), Positives = 97/178 (54%), Gaps = 3/178 (1%)
 Frame = +1

Query: 738 EFHCGFEDGNICLFTQDDTDNFDWTKQSTATRNTKYTPNTGPSADRSGSKEGFYMYIETS 797
           E  C F+ G IC +TQ  +D+FDW + S +T +T   P    +   +G   G+YMY E S
Sbjct: 196 ELGCDFDSG-ICGYTQSRSDDFDWVRHSGSTGSTGTGPTVDHT---TGINLGYYMYTEAS 363

Query: 798 RPRLEGEKARLLSPVFSIAPKNPYGPTNSAYCFSFFYHMYGQHIGVLNVYLRLKGQTTIE 857
            PR  G+ A LLS            P++   C SFFYHMYG  +G LN  L+++  T + 
Sbjct: 364 SPRHXGDNAVLLS--------KEQCPSSIDICVSFFYHMYGNSMGTLN--LKVRNSTGLS 513

Query: 858 NPLWSSSGNKGQRWNEAHVNI---YPITSFQLIFEGIRGPGIEGDIAIDDVSIAEGEC 912
            PL++ SG+ G  W +A VNI   Y    + L FEGI G G   D+AIDD+++  G C
Sbjct: 514 QPLFTKSGDAGNVWLKAAVNIPADYLRAPYALAFEGIIGSGYYSDMAIDDITVHLGIC 687
>19336
          Length = 453

 Score = 90.1 bits (222), Expect = 4e-18,   Method: Compositional matrix adjust.
 Identities = 55/138 (39%), Positives = 74/138 (53%), Gaps = 2/138 (1%)
 Frame = +3

Query: 777 TGPSADRSG-SKEGFYMYIETSRPRLEGEKARLLSPVFSIAPKNPYGPTNSAYCFSFFYH 835
           TGPS D +  +  G+Y YI+TS PR   + A + SP               + CF+F+YH
Sbjct: 6   TGPSHDHTTRNGYGYYAYIKTSAPRRPNDNAIMTSPQIP--------SFTGSKCFTFWYH 161

Query: 836 MYGQHIGVLNVYLRLKGQTTIENPLWSSSGNKGQRWNEAHVNIYPIT-SFQLIFEGIRGP 894
           M G  IG LNVYL + GQ  +  P+++ S   G  W +A   I   T S+Q+ FEG+ G 
Sbjct: 162 MNGTQIGALNVYLIVNGQ-RMNTPIFTQSQRLGNYWIQAAYTIPTQTNSWQIAFEGVVGG 338

Query: 895 GIEGDIAIDDVSIAEGEC 912
           G  GDIAIDD+    G C
Sbjct: 339 GYSGDIAIDDIKFRSGAC 392
>13135
          Length = 849

 Score = 59.3 bits (142), Expect = 8e-09,   Method: Compositional matrix adjust.
 Identities = 55/229 (24%), Positives = 97/229 (42%), Gaps = 10/229 (4%)
 Frame = -1

Query: 350 QIGREVKISCQVEAVPSEELTFSWF----KNGRPLRSSERMVITQTDP-----DV-SPGT 399
           +I ++V++ C VE  P ++    W     +NG        +     DP     D+ SP +
Sbjct: 678 EINKDVQLXCVVENKPIDK-EVQWVGTVVRNGTTRTIPVSIATRSYDPFKYSIDLPSPTS 502

Query: 400 TNLDIIDLKFTDFGTYTCVASLKGGGXXXXXXXXXXXXXTVPPNLTVPQEKSPLVTREGD 459
             L I + + TD G YTC   L                    P ++     S +   EG 
Sbjct: 501 WRLRIQNGQVTDEGVYTCQVQLSNQNYAKAFHQLVIIQM---PQISDLDTSSDVSKSEGQ 331

Query: 460 TIELQCQVTGKPKPIILWSRADKEVAMPDGTMQMESYDGTLRIVNVSREMSGMYRCQTSQ 519
           ++ L+C  +G+P P + W+R   E+    G   +ES    L I  +  E +G+Y+C +S 
Sbjct: 330 SLVLRCHASGRPTPSVKWTRMAGELLPSGGREHLES---DLVIPQLKPEHAGIYKCSSSN 160

Query: 520 YNGFNVKPREALVQLIVQYPPAVEPAFLEIRQGQDRSVTMSCRVLRAYP 568
             G + +     +++ V + P +  A   ++Q Q     + C V++ YP
Sbjct: 159 SAGSDFRN----IRVTVNFAPVLSSANTVVQQAQGYVKELVC-VVKGYP 28

 Score = 44.7 bits (104), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 31/112 (27%), Positives = 53/112 (47%)
 Frame = -1

Query: 54  EGETLELTCLVTGHPRPQIRWTKTAGSASDRFQDSSVFNETLRITNIQRHQGGRYYCKAE 113
           EG++L L C  +G P P ++WT+ AG          + ++ L I  ++    G Y C + 
Sbjct: 339 EGQSLVLRCHASGRPTPSVKWTRMAGELLPSGGREHLESD-LVIPQLKPEHAGIYKCSSS 163

Query: 114 NGLGSPAIKSIRVDVYYLDDPVVTVHQSIGEAKEQFYYERTVFLRCVANSNP 165
           N  GS   ++IRV V +   PV++   ++ +  + +  E    L CV    P
Sbjct: 162 NSAGS-DFRNIRVTVNFA--PVLSSANTVVQQAQGYVKE----LVCVVKGYP 28

 Score = 40.8 bits (94), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 50/210 (23%), Positives = 89/210 (42%), Gaps = 23/210 (10%)
 Frame = -1

Query: 132 DDPVVTVHQS---IGEAKEQFYYE--RTVFLRCVANSNPPVRYSWRRGQEVLLQGSDKGV 186
           DDP+V++ ++   + E +     E  + V L CV   N P+    +    V+  G+ + +
Sbjct: 747 DDPIVSIIETNPVLDEVEGNIISEINKDVQLXCVVE-NKPIDKEVQWVGTVVRNGTTRTI 571

Query: 187 EI------YEPF-----FTQGETKILKLKNLRPQDYANYSCIASVRNVCNIPDKMVSFRL 235
            +      Y+PF          +  L+++N +  D   Y+C   + N     +   +F  
Sbjct: 570 PVSIATRSYDPFKYSIDLPSPTSWRLRIQNGQVTDEGVYTCQVQLSN----QNYAKAFHQ 403

Query: 236 SNKTASPSIKLL-VDDPIVVNPGEAITLVCVTTGGEPTPSLTWVRSFGTLPEKIVLNGG- 293
                 P I  L     +  + G+++ L C    G PTPS+ W R  G L    + +GG 
Sbjct: 402 LVIIQMPQISDLDTSSDVSKSEGQSLVLRC-HASGRPTPSVKWTRMAGEL----LPSGGR 238

Query: 294 -----TLTIPAITSDDAGTYSCIANNNVGN 318
                 L IP +  + AG Y C ++N+ G+
Sbjct: 237 EHLESDLVIPQLKPEHAGIYKCSSSNSAGS 148

 Score = 35.4 bits (80), Expect = 0.096,   Method: Compositional matrix adjust.
 Identities = 34/123 (27%), Positives = 56/123 (45%), Gaps = 3/123 (2%)
 Frame = -1

Query: 500 LRIVNVSREMSGMYRCQTSQYNGFNVKPREALVQLIVQYPPAVE-PAFLEIRQGQDRSVT 558
           LRI N      G+Y CQ    N    K    LV  I+Q P   +     ++ + + +S+ 
Sbjct: 495 LRIQNGQVTDEGVYTCQVQLSNQNYAKAFHQLV--IIQMPQISDLDTSSDVSKSEGQSLV 322

Query: 559 MSCRVL-RAYPIRVLTYEW-RLGNKLLRTGQFDSQEYTEYPLKSLSNENYGVYNCSIINE 616
           + C    R  P    + +W R+  +LL +G  +  E ++  +  L  E+ G+Y CS  N 
Sbjct: 321 LRCHASGRPTP----SVKWTRMAGELLPSGGREHLE-SDLVIPQLKPEHAGIYKCSSSNS 157

Query: 617 AGA 619
           AG+
Sbjct: 156 AGS 148
>09987
          Length = 1666

 Score = 56.6 bits (135), Expect = 5e-08,   Method: Compositional matrix adjust.
 Identities = 52/175 (29%), Positives = 75/175 (42%), Gaps = 5/175 (2%)
 Frame = -1

Query: 747  NICLFTQ-DDTDNFDWTKQSTATRNTKYTPNTGPSADRSGSK-EGFYMYIETSRPRLEGE 804
            N+C ++Q   TD  DW   S  T  T   PN   +    GS+    Y+Y+E       G+
Sbjct: 1663 NLCAWSQVQGTDXMDWKINSGPTHTTGTGPNQ--AMPLPGSQVNNKYLYLE-GNDGFPGD 1493

Query: 805  KARLLSPVFSIAPKNPYGPTNSAYCFSFFYHMYGQHIGVLNVYLRLKGQTTIENPLWSSS 864
             A + + +  +     +GP     C  F+YHM G  +G L V     G TT    L  +S
Sbjct: 1492 MAEIRTGLLHL-----HGP----ICLQFYYHMKGIGLGELEVRKEELGVTT--TLLTRTS 1346

Query: 865  GNKGQRWNEAHVNIYPITSF---QLIFEGIRGPGIEGDIAIDDVSIAEGECAKQD 916
             ++   W  A V I P       Q+I   +RG     DIAID ++   G C + D
Sbjct: 1345 NDQTTDWTPARVTITPHDLHHPTQVIIRAVRGLSSSTDIAIDLLTGLTGSCDQYD 1181
>20110
          Length = 820

 Score = 52.8 bits (125), Expect = 6e-07,   Method: Compositional matrix adjust.
 Identities = 44/153 (28%), Positives = 71/153 (46%), Gaps = 5/153 (3%)
 Frame = -1

Query: 181 GSDKGVEIYEPFFTQGETKILKLKNLRPQDYANYSCIASVRNVC--NIPDKMVSFRLSNK 238
           G  +  E+ +      ET +L ++ L   D   Y+C   +  V     P K+ +  +   
Sbjct: 733 GGLRKYEVQKRLSGDRETYMLVVRRLVETDAGIYTCTVRITAVSYEEWPTKIGNLTVQ-- 560

Query: 239 TASPSIKLLVDDPIV-VNPGEAITLVCVTTGGEPTPSLTWVRSFGT-LPEKIV-LNGGTL 295
              PSIK      ++ +  G+  TLVC  +G  P P++TW RS G  LP  +      TL
Sbjct: 559 -VPPSIKPGDTTAVLQIEQGQNSTLVCAASG-IPAPNITWTRSDGGFLPIGVAQFRSATL 386

Query: 296 TIPAITSDDAGTYSCIANNNVGNPAKKSTNIIV 328
            +  +T  D G Y C+A+NN+  PA+    ++V
Sbjct: 385 PMNNVTVRDMGVYRCVADNNIKPPAEHLAEVLV 287

 Score = 52.0 bits (123), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 40/135 (29%), Positives = 57/135 (42%), Gaps = 1/135 (0%)
 Frame = -1

Query: 407 LKFTDFGTYTCVASLKGGGXXXXXXXXXXXXXTVPPNLTVPQEKSPLVTREGDTIELQCQ 466
           L  TD G YTC   +                  VPP++      + L   +G    L C 
Sbjct: 658 LVETDAGIYTCTVRITAVSYEEWPTKIGNLTVQVPPSIKPGDTTAVLQIEQGQNSTLVCA 479

Query: 467 VTGKPKPIILWSRADKEVAMPDGTMQMESYDGTLRIVNVSREMSGMYRCQTSQYNGFNVK 526
            +G P P I W+R+D    +P G  Q  S   TL + NV+    G+YRC        N+K
Sbjct: 478 ASGIPAPNITWTRSDGGF-LPIGVAQFRS--ATLPMNNVTVRDMGVYRCVADN----NIK 320

Query: 527 -PREALVQLIVQYPP 540
            P E L +++V + P
Sbjct: 319 PPAEHLAEVLVFHAP 275

 Score = 40.4 bits (93), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 25/86 (29%), Positives = 39/86 (45%), Gaps = 4/86 (4%)
 Frame = -1

Query: 49  VYTIREGETLELTCLVTGHPRPQIRWTKTAGS----ASDRFQDSSVFNETLRITNIQRHQ 104
           V  I +G+   L C  +G P P I WT++ G        +F+ +     TL + N+    
Sbjct: 523 VLQIEQGQNSTLVCAASGIPAPNITWTRSDGGFLPIGVAQFRSA-----TLPMNNVTVRD 359

Query: 105 GGRYYCKAENGLGSPAIKSIRVDVYY 130
            G Y C A+N +  PA     V V++
Sbjct: 358 MGVYRCVADNNIKPPAEHLAEVLVFH 281
>27666
          Length = 873

 Score = 51.2 bits (121), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 54/222 (24%), Positives = 86/222 (38%), Gaps = 2/222 (0%)
 Frame = +1

Query: 336 FWITPDPYHKDDNIQIGREVKISCQVEAVPSEELTFSWFKNGRPLRSSERMVITQTDPDV 395
           FWI     H+D    I  +  ++ Q+  +      F   ++G P R +  +VI +     
Sbjct: 259 FWI-----HQDTGELISMDKAVTLQINQMIGGLRKFEIVQHGPPDRLTFTLVIRR----- 408

Query: 396 SPGTTNLDIIDLKFTDFGTYTCVASLKGGGXXXXXXXXXXXXXTVPPNLTVPQEKSPLV- 454
                      L+  D GTY C   ++                 VPP +  P E + LV 
Sbjct: 409 -----------LRQQDAGTYVCQVKIQNENILSQVQKIGTLTVQVPPKIR-PGETTTLVE 552

Query: 455 TREGDTIELQCQVTGKPKPIILWSRADKEVAMPDGTMQMESYDGTLRIVNVSREMSGMYR 514
             +     L C  TG P P I W+R D   A+P G  Q    +  L +   + +  G+YR
Sbjct: 553 IDQNQNSSLVCSSTGIPAPNITWTRLDGR-ALPTGYSQFRGRE--LPLNGATVDHMGVYR 723

Query: 515 CQTSQYNGFNVK-PREALVQLIVQYPPAVEPAFLEIRQGQDR 555
           C  +     N+K P + L ++ V + P        + Q Q+R
Sbjct: 724 CVANN----NIKPPDDHLCEVRVFHAPTARTVQNSVGQAQNR 837

 Score = 47.4 bits (111), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 39/125 (31%), Positives = 57/125 (45%), Gaps = 3/125 (2%)
 Frame = +1

Query: 198 TKILKLKNLRPQDYANYSCIASVRNVCNIPDKMVSFRLSNKTASPSIKLLVDDPIV-VNP 256
           T  L ++ LR QD   Y C   ++N  NI  ++           P I+      +V ++ 
Sbjct: 385 TFTLVIRRLRQQDAGTYVCQVKIQNE-NILSQVQKIGTLTVQVPPKIRPGETTTLVEIDQ 561

Query: 257 GEAITLVCVTTGGEPTPSLTWVRSFG-TLPEKIV-LNGGTLTIPAITSDDAGTYSCIANN 314
            +  +LVC +TG  P P++TW R  G  LP       G  L +   T D  G Y C+ANN
Sbjct: 562 NQNSSLVCSSTG-IPAPNITWTRLDGRALPTGYSQFRGRELPLNGATVDHMGVYRCVANN 738

Query: 315 NVGNP 319
           N+  P
Sbjct: 739 NIKPP 753

 Score = 33.5 bits (75), Expect = 0.42,   Method: Compositional matrix adjust.
 Identities = 27/97 (27%), Positives = 38/97 (39%)
 Frame = +1

Query: 52  IREGETLELTCLVTGHPRPQIRWTKTAGSASDRFQDSSVFNETLRITNIQRHQGGRYYCK 111
           I + +   L C  TG P P I WT+  G A      S      L +        G Y C 
Sbjct: 553 IDQNQNSSLVCSSTGIPAPNITWTRLDGRALPTGY-SQFRGRELPLNGATVDHMGVYRCV 729

Query: 112 AENGLGSPAIKSIRVDVYYLDDPVVTVHQSIGEAKEQ 148
           A N +  P      V V++      TV  S+G+A+ +
Sbjct: 730 ANNNIKPPDDHLCEVRVFHAPT-ARTVQNSVGQAQNR 837
>29990
          Length = 434

 Score = 45.8 bits (107), Expect(2) = 1e-05,   Method: Compositional matrix adjust.
 Identities = 26/78 (33%), Positives = 34/78 (43%)
 Frame = +3

Query: 402 LDIIDLKFTDFGTYTCVASLKGGGXXXXXXXXXXXXXTVPPNLTVPQEKSPLVTREGDTI 461
           L I D +  D G Y C+A    G               V P  T  Q    +VT EG T+
Sbjct: 99  LMIEDAQDDDRGVYECIARNVAGETHSNQVELRYFGERVAPXFT--QRPQDIVTVEGQTV 272

Query: 462 ELQCQVTGKPKPIILWSR 479
           +L CQ +G P+P   W+R
Sbjct: 273 QLVCQASGHPRPTFSWTR 326

 Score = 21.9 bits (45), Expect(2) = 1e-05,   Method: Composition-based stats.
 Identities = 10/19 (52%), Positives = 11/19 (57%)
 Frame = +2

Query: 497 DGTLRIVNVSREMSGMYRC 515
           DGTL I NV     G Y+C
Sbjct: 371 DGTLTIRNVQESDRGDYQC 427

 Score = 41.6 bits (96), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 34/122 (27%), Positives = 52/122 (42%), Gaps = 7/122 (5%)
 Frame = +3

Query: 269 GEPTPSLTWVRSFGTL-----PEKIVLNGGTLTIPAITSDDAGTYSCIANNNVGNPAKKS 323
           G+P P + W+ +   +         +L+ GTL I     DD G Y CIA N  G     S
Sbjct: 6   GKPVPEIVWMHNNNRVEISGDSRFSLLHDGTLMIEDAQDDDRGVYECIARNVAGE--THS 179

Query: 324 TNIIVRALKKGRFWITPDPYHKDDNIQI--GREVKISCQVEAVPSEELTFSWFKNGRPLR 381
             + +R   +    + P    +  +I    G+ V++ CQ    P    TFSW +N   L 
Sbjct: 180 NQVELRYFGER---VAPXFTQRPQDIVTVEGQTVQLVCQASGHPRP--TFSWTRNLEQLG 344

Query: 382 SS 383
           S+
Sbjct: 345 ST 350

 Score = 37.0 bits (84), Expect(2) = 0.014,   Method: Compositional matrix adjust.
 Identities = 25/87 (28%), Positives = 41/87 (47%), Gaps = 12/87 (13%)
 Frame = +3

Query: 2   DLVYGLVWLLTVLLEGI--SGQGVYAPPTVRIVHSGLACNIEEERYSERV---YTIR--- 53
           D  + L+   T+++E      +GVY      +     +  +E   + ERV   +T R   
Sbjct: 66  DSRFSLLHDGTLMIEDAQDDDRGVYECIARNVAGETHSNQVELRYFGERVAPXFTQRPQD 245

Query: 54  ----EGETLELTCLVTGHPRPQIRWTK 76
               EG+T++L C  +GHPRP   WT+
Sbjct: 246 IVTVEGQTVQLVCQASGHPRPTFSWTR 326

 Score = 20.4 bits (41), Expect(2) = 0.014,   Method: Composition-based stats.
 Identities = 9/19 (47%), Positives = 10/19 (52%)
 Frame = +2

Query: 94  TLRITNIQRHQGGRYYCKA 112
           TL I N+Q    G Y C A
Sbjct: 377 TLTIRNVQESDRGDYQCYA 433

 Score = 31.6 bits (70), Expect = 1.7,   Method: Compositional matrix adjust.
 Identities = 15/47 (31%), Positives = 23/47 (48%)
 Frame = +3

Query: 469 GKPKPIILWSRADKEVAMPDGTMQMESYDGTLRIVNVSREMSGMYRC 515
           GKP P I+W   +  V +   +     +DGTL I +   +  G+Y C
Sbjct: 6   GKPVPEIVWMHNNNRVEISGDSRFSLLHDGTLMIEDAQDDDRGVYEC 146
>18345
          Length = 461

 Score = 47.4 bits (111), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 28/81 (34%), Positives = 40/81 (49%), Gaps = 1/81 (1%)
 Frame = +1

Query: 51  TIREGETLELTCLVTGHPRPQIRWTKTAGSASDRFQDS-SVFNETLRITNIQRHQGGRYY 109
           +++EG+T  L C VTG P P + W K      D  ++        L + N+ RH    Y 
Sbjct: 145 SLKEGDTATLVCNVTGVPSPDVTWYKRNTRQLDAQKERVGSTGPVLVMYNVTRHCDDIYE 324

Query: 110 CKAENGLGSPAIKSIRVDVYY 130
           C A+NG+     K+IRV V Y
Sbjct: 325 CYADNGVPPAVTKAIRVTVDY 387

 Score = 36.6 bits (83), Expect = 0.047,   Method: Compositional matrix adjust.
 Identities = 26/89 (29%), Positives = 39/89 (43%), Gaps = 1/89 (1%)
 Frame = +1

Query: 456 REGDTIELQCQVTGKPKPIILWSRADKEVAMPDGTMQMESYDGTLRIVNVSREMSGMYRC 515
           +EGDT  L C VTG P P + W + +    +     ++ S    L + NV+R    +Y C
Sbjct: 151 KEGDTATLVCNVTGVPSPDVTWYKRNTR-QLDAQKERVGSTGPVLVMYNVTRHCDDIYEC 327

Query: 516 QTSQYNGFNVKPR-EALVQLIVQYPPAVE 543
               Y    V P     +++ V Y P V 
Sbjct: 328 ----YADNGVPPAVTKAIRVTVDYAPEVH 402
>06028
          Length = 1358

 Score = 46.2 bits (108), Expect = 7e-05,   Method: Compositional matrix adjust.
 Identities = 55/234 (23%), Positives = 88/234 (37%), Gaps = 15/234 (6%)
 Frame = +1

Query: 295 LTIPAITSDDAGTYSCIANNNVGNPAKKSTNIIVRALKKGRFWITPDPYHKDDN------ 348
           L I      D+G Y C+A+N  G   K S  +  +  ++     T   +H+D N      
Sbjct: 85  LIIHNPVEKDSGVYFCVASNE-GAQNKISHQVDFKGRERFTLEKTAGFFHRDPNKPHFLN 261

Query: 349 ------IQIGREVKISCQVEAVPSEELTFSWFKNGRPLRSSERMVITQTDPDVSPGTTNL 402
                 +  G  V IS +     S  +   W +N RP+         +       G   L
Sbjct: 262 PLGNQTVCHGGTVAISAEF-MQSSTPIEVKWLRNRRPVDGPSVQTFNER------GIYTL 420

Query: 403 DIIDLKFTDFGTYTCVASLKGGGXXXXXXXXXX--XXXTVPPNLTVPQEKSPLVTREGDT 460
            I++      GTYTC+AS   G                 V P L + + ++ +    GD 
Sbjct: 421 AIMNAGEEHEGTYTCLASNAFGRIESHVNIDVAVGVEKEVRPPLFLSRPETEMKIAVGDP 600

Query: 461 IELQCQVTGKPKPIILWSRADKEVAMPDGTMQMESYDGTLRIVNVSR-EMSGMY 513
             L  ++ G PKP +++ +  K++   D   +  S D T   V  S+   SG Y
Sbjct: 601 FSLSFRIAGDPKPRLVFMKGTKDITQSDRVSKEVSDDYTRFTVQKSQISDSGTY 762

 Score = 33.5 bits (75), Expect = 0.45,   Method: Compositional matrix adjust.
 Identities = 54/243 (22%), Positives = 90/243 (37%), Gaps = 24/243 (9%)
 Frame = +1

Query: 201 LKLKNLRPQDYANYSCIASVRNVCNIPDKMVSF----RLSNKTASPSIKLLVDDPIVVNP 256
           L + N   +D   Y C+AS     N     V F    R + +  +       + P  +NP
Sbjct: 85  LIIHNPVEKDSGVYFCVASNEGAQNKISHQVDFKGRERFTLEKTAGFFHRDPNKPHFLNP 264

Query: 257 --------GEAITLVCVTTGGEPTPSLTWVR--------SFGTLPEKIVLNGGTLTIPAI 300
                   G  + +            + W+R        S  T  E+ +    TL I   
Sbjct: 265 LGNQTVCHGGTVAISAEFMQSSTPIEVKWLRNRRPVDGPSVQTFNERGIY---TLAIMNA 435

Query: 301 TSDDAGTYSCIANNNVGN-PAKKSTNIIVRALKKGR---FWITPDPYHKDDNIQIGREVK 356
             +  GTY+C+A+N  G   +  + ++ V   K+ R   F   P+   K   I +G    
Sbjct: 436 GEEHEGTYTCLASNAFGRIESHVNIDVAVGVEKEVRPPLFLSRPETEMK---IAVGDPFS 606

Query: 357 ISCQVEAVPSEELTFSWFKNGRPLRSSERMVITQTDPDVSPGTTNLDIIDLKFTDFGTYT 416
           +S ++   P   L F   K  + +  S+R+       +VS   T   +   + +D GTY 
Sbjct: 607 LSFRIAGDPKPRLVF--MKGTKDITQSDRV-----SKEVSDDYTRFTVQKSQISDSGTYF 765

Query: 417 CVA 419
            VA
Sbjct: 766 VVA 774
>19356
          Length = 451

 Score = 45.8 bits (107), Expect = 8e-05,   Method: Compositional matrix adjust.
 Identities = 28/77 (36%), Positives = 35/77 (45%)
 Frame = -2

Query: 348 NIQIGREVKISCQVEAVPSEELTFSWFKNGRPLRSSERMVITQTDPDVSPGTTNLDIIDL 407
           N+Q G+ V +  +V  +    L   WFKNGRPL +  R  I         G   LDII +
Sbjct: 249 NLQGGQSVHLETRVIPITDSSLVIEWFKNGRPLNNGCRFNIV-----FDRGFAILDIIGV 85

Query: 408 KFTDFGTYTCVASLKGG 424
              D G Y C A  K G
Sbjct: 84  ISEDTGDYFCFARNKAG 34
>34811
          Length = 613

 Score = 42.4 bits (98), Expect = 8e-04,   Method: Compositional matrix adjust.
 Identities = 35/131 (26%), Positives = 53/131 (40%), Gaps = 3/131 (2%)
 Frame = +1

Query: 291 NGGTLTIPAITSDDAGTYSCIANNNVGNPAKKSTNIIV-RALKKGRFWITPDPYHKD--D 347
           N   L+ P I   DAG YSC A++ +  P   ST  +  +          P     D  D
Sbjct: 61  NSEVLSFPQIRRADAGNYSCKASSLLKVPGVGSTETVFGQGFTTINVQYAPGAASIDKID 240

Query: 348 NIQIGREVKISCQVEAVPSEELTFSWFKNGRPLRSSERMVITQTDPDVSPGTTNLDIIDL 407
           NI +G+ ++++C        E  F W +NG     +E+   +QTD        N  I   
Sbjct: 241 NIDVGQRLQLTCSAAPQGFPEARFKWHRNG-----AEQ---SQTD-------ANYVIXST 375

Query: 408 KFTDFGTYTCV 418
             +D   Y+C 
Sbjct: 376 ALSDTAVYSCT 408
>08294
          Length = 1849

 Score = 42.0 bits (97), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 31/108 (28%), Positives = 45/108 (41%)
 Frame = +2

Query: 415 YTCVASLKGGGXXXXXXXXXXXXXTVPPNLTVPQEKSPLVTREGDTIELQCQVTGKPKPI 474
           YTCVA+    G                P +TV  + + +   EG +  L C   G P P 
Sbjct: 5   YTCVATHPRQGVINATIHISIVEW---PAITV--KSNNITVFEGHSAILHCVAKGSPSPD 169

Query: 475 ILWSRADKEVAMPDGTMQMESYDGTLRIVNVSREMSGMYRCQTSQYNG 522
           I W R D +  +P+        +GT++I  V  E +GMY C  +   G
Sbjct: 170 IAWYR-DSQPILPNARRYTLFKNGTMKIRQVFMEDNGMYACVANNTAG 310

 Score = 42.0 bits (97), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 30/99 (30%), Positives = 48/99 (48%), Gaps = 4/99 (4%)
 Frame = +2

Query: 242 PSIKLLVDDPIVVNPGEAITLVCVTTGGEPTPSLTWVR-SFGTLPEK---IVLNGGTLTI 297
           P+I +  ++ I V  G +  L CV  G  P+P + W R S   LP      +   GT+ I
Sbjct: 77  PAITVKSNN-ITVFEGHSAILHCVAKG-SPSPDIAWYRDSQPILPNARRYTLFKNGTMKI 250

Query: 298 PAITSDDAGTYSCIANNNVGNPAKKSTNIIVRALKKGRF 336
             +  +D G Y+C+ANN  G P   +++  +R +   R 
Sbjct: 251 RQVFMEDNGMYACVANNTAG-PLAGTSSFALRTMHWRRM 364

 Score = 37.7 bits (86), Expect = 0.025,   Method: Compositional matrix adjust.
 Identities = 20/68 (29%), Positives = 31/68 (45%), Gaps = 1/68 (1%)
 Frame = +2

Query: 51  TIREGETLELTCLVTGHPRPQIRWTKTAGSASDRFQDSSVF-NETLRITNIQRHQGGRYY 109
           T+ EG +  L C+  G P P I W + +       +  ++F N T++I  +     G Y 
Sbjct: 107 TVFEGHSAILHCVAKGSPSPDIAWYRDSQPILPNARRYTLFKNGTMKIRQVFMEDNGMYA 286

Query: 110 CKAENGLG 117
           C A N  G
Sbjct: 287 CVANNTAG 310
>29932
          Length = 748

 Score = 40.4 bits (93), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 28/89 (31%), Positives = 40/89 (44%), Gaps = 1/89 (1%)
 Frame = +3

Query: 242 PSIKLLVDDPIVVNPGEAITLVCVTTGGEPTPSLTWVRSFG-TLPEKIVLNGGTLTIPAI 300
           P I    + P+ V     I + C  T   P  ++ W       LP  + ++G  L   AI
Sbjct: 93  PQITFRPNIPLEVEADRNIEIYCDVTNARPE-NVQWATDNNRPLPGSVHIDGQILRFVAI 269

Query: 301 TSDDAGTYSCIANNNVGNPAKKSTNIIVR 329
           T  DAG YSC A+N  G    K+  ++VR
Sbjct: 270 TPADAGGYSCTASNKYGT-NSKTAQVVVR 353

 Score = 29.6 bits (65), Expect = 5.6,   Method: Compositional matrix adjust.
 Identities = 26/101 (25%), Positives = 42/101 (41%)
 Frame = +3

Query: 452 PLVTREGDTIELQCQVTGKPKPIILWSRADKEVAMPDGTMQMESYDGTLRIVNVSREMSG 511
           PL       IE+ C VT      + W+  D    +P G++ ++     LR V ++   +G
Sbjct: 120 PLEVEADRNIEIYCDVTNARPENVQWA-TDNNRPLP-GSVHIDGQ--ILRFVAITPADAG 287

Query: 512 MYRCQTSQYNGFNVKPREALVQLIVQYPPAVEPAFLEIRQG 552
            Y C  S   G N K  + +V+    Y    +    E R+G
Sbjct: 288 GYSCTASNKYGTNSKTAQVVVRPPTFYTQQPQSELQERREG 410
>06343
          Length = 1647

 Score = 39.3 bits (90), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 53/246 (21%), Positives = 98/246 (39%), Gaps = 17/246 (6%)
 Frame = -2

Query: 689  KINGNIQKGELITYNLTEL-----------IKPEAYEVRLTPLTKFGEGDSTIRVIKYTG 737
            +IN N++     +  LT L           I+P   E     L   G  D  +    + G
Sbjct: 1448 RINVNVEARSPFSVQLTFLPVMYMDKEAVDIEPCRCENPDIDLVLDGSHDHRLLSCHFEG 1269

Query: 738  EFHCGFEDGNICLFTQDDTDNFDWTKQSTATRNTKYTPNTGPSADRSGSKEGFYMYIETS 797
              H G      C +T+   +     ++S A+ +  Y+P + P      + E +  Y E  
Sbjct: 1268 RGHVGR-----CEWTRTSGE-----EESGASTSQWYSPPSSPLLSGFATGEDYERYFEAF 1119

Query: 798  RPRLEGEKARLLSPVFSIAPKNPYGPTNSAYCFSFFYHMYGQHIGVLNVYLRLK---GQT 854
               +EG   +++   F ++  +         C   + + +G+   VL+++L  +   G+ 
Sbjct: 1118 PVVVEGGTNQVIKRHFVVS--DWLTLKAEPGCLRLWLYAWGRMPAVLHLFLHQRTGEGKX 945

Query: 855  TIENPLWSSSGNKGQ--RWNEAHVNIYPITSFQLIFEGIRGP-GIEGDIAIDDVSIAEGE 911
                 LW+    +G    W E H+ +      ++I E IRG  G  G + +DDVS     
Sbjct: 944  DSLIDLWTMPRPRGYLITWMEEHILVEYEGEIRIIVE-IRGDIGWPGSLVVDDVSAPXEA 768

Query: 912  CAKQDL 917
            C+ ++L
Sbjct: 767  CSGKNL 750
>17530
          Length = 503

 Score = 37.4 bits (85), Expect = 0.029,   Method: Compositional matrix adjust.
 Identities = 28/122 (22%), Positives = 53/122 (43%), Gaps = 13/122 (10%)
 Frame = +2

Query: 257 GEAITLVCVTTGGEPTPSLTWVRSFGTLPEKI--------VLNGG----TLTIPAITSDD 304
           G+ +   C ++GG P P++TW ++   L   +          +GG    T+++    SD 
Sbjct: 107 GQRVRFTCSSSGGNPPPTITWTKNGVQLINGVQQIGVGQTSTSGGSTRNTVSVVMDHSDH 286

Query: 305 AGTYSCIANNNVGNPAKKSTNIIVRALKKGRFWITP-DPYHKDDNIQIGREVKISCQVEA 363
              Y+C   N V   +  + ++++           P  PY     +++ R   I+CQV+A
Sbjct: 287 QANYTCFVYNQVNINSSLTASVVLNVRYSPIITFEPFSPYI----VRLDRPANITCQVDA 454

Query: 364 VP 365
            P
Sbjct: 455 NP 460
>25766
          Length = 469

 Score = 29.6 bits (65), Expect(2) = 0.082,   Method: Compositional matrix adjust.
 Identities = 10/22 (45%), Positives = 15/22 (68%)
 Frame = +1

Query: 55  GETLELTCLVTGHPRPQIRWTK 76
           G +++  C V+G P PQ+RW K
Sbjct: 220 GSSVKFHCDVSGDPVPQVRWEK 285

 Score = 25.0 bits (53), Expect(2) = 0.082,   Method: Compositional matrix adjust.
 Identities = 13/29 (44%), Positives = 17/29 (58%), Gaps = 2/29 (6%)
 Frame = +3

Query: 90  VFNETLRITNIQRHQGGRYYCKA--ENGL 116
           + N  L + NIQ+   GRY C A  ENG+
Sbjct: 315 IRNGILTLYNIQKEDEGRYICTASSENGV 401

 Score = 34.7 bits (78), Expect = 0.18,   Method: Compositional matrix adjust.
 Identities = 26/91 (28%), Positives = 37/91 (40%), Gaps = 2/91 (2%)
 Frame = +1

Query: 277 WVRSFGTLPEKIVLNGGTLTIPAITSDDAGTYSCIANNNVGNPAKKSTNIIVRALKKGRF 336
           W R+ G + E      G L IP +T+ DAG Y C+  ++ G        I        R 
Sbjct: 25  WRRAAGRVREY----DGILQIPRVTAADAGRYRCVITSSEG--------ITSEGFATLRI 168

Query: 337 WITP--DPYHKDDNIQIGREVKISCQVEAVP 365
              P      +++N Q+G  VK  C V   P
Sbjct: 169 SSPPVVSVKQRNENRQVGSSVKFHCDVSGDP 261

 Score = 30.4 bits (67), Expect = 3.3,   Method: Compositional matrix adjust.
 Identities = 20/58 (34%), Positives = 27/58 (46%)
 Frame = +3

Query: 260 ITLVCVTTGGEPTPSLTWVRSFGTLPEKIVLNGGTLTIPAITSDDAGTYSCIANNNVG 317
           I L CV   G P  S    +  G LP +  +  G LT+  I  +D G Y C A++  G
Sbjct: 234 IPL*CV---GRPCSSSPLGKESGQLPAQHQIRNGILTLYNIQKEDEGRYICTASSENG 398

 Score = 30.0 bits (66), Expect = 4.4,   Method: Compositional matrix adjust.
 Identities = 16/51 (31%), Positives = 23/51 (45%)
 Frame = +1

Query: 492 QMESYDGTLRIVNVSREMSGMYRCQTSQYNGFNVKPREALVQLIVQYPPAV 542
           ++  YDG L+I  V+   +G YRC  +   G      E    L +  PP V
Sbjct: 43  RVREYDGILQIPRVTAADAGRYRCVITSSEGIT---SEGFATLRISSPPVV 186
>11855
          Length = 1574

 Score = 35.8 bits (81), Expect = 0.082,   Method: Compositional matrix adjust.
 Identities = 24/74 (32%), Positives = 37/74 (50%), Gaps = 3/74 (4%)
 Frame = +1

Query: 54  EGETLELTCLVTGHPRPQIRWTKTAGSA--SDRFQDSSVFNETLRITNIQRHQG-GRYYC 110
           E  T++L C  +G+P P I W     ++   +  Q S   N  L I +I   +  G Y C
Sbjct: 355 ETTTVQLFCRASGYPEPTITWYDGRNNSLPDNSGQFSIAVNGDLIIRDISWSENMGVYRC 534

Query: 111 KAENGLGSPAIKSI 124
            AEN LGS ++++ 
Sbjct: 535 VAENELGSHSVQAF 576

 Score = 35.8 bits (81), Expect = 0.093,   Method: Compositional matrix adjust.
 Identities = 21/61 (34%), Positives = 35/61 (57%), Gaps = 2/61 (3%)
 Frame = +1

Query: 457 EGDTIELQCQVTGKPKPIILWSRADKEVAMPDGTMQME-SYDGTLRIVNVS-REMSGMYR 514
           E  T++L C+ +G P+P I W    +  ++PD + Q   + +G L I ++S  E  G+YR
Sbjct: 355 ETTTVQLFCRASGYPEPTITWYDG-RNNSLPDNSGQFSIAVNGDLIIRDISWSENMGVYR 531

Query: 515 C 515
           C
Sbjct: 532 C 534

 Score = 30.4 bits (67), Expect = 3.6,   Method: Compositional matrix adjust.
 Identities = 19/65 (29%), Positives = 32/65 (49%), Gaps = 6/65 (9%)
 Frame = +1

Query: 260 ITLVCVTTGGEPTPSLTWVRSFG-TLPE-----KIVLNGGTLTIPAITSDDAGTYSCIAN 313
           + L C  +G  P P++TW      +LP+      I +NG  +      S++ G Y C+A 
Sbjct: 367 VQLFCRASG-YPEPTITWYDGRNNSLPDNSGQFSIAVNGDLIIRDISWSENMGVYRCVAE 543

Query: 314 NNVGN 318
           N +G+
Sbjct: 544 NELGS 558
>38127
          Length = 860

 Score = 35.0 bits (79), Expect = 0.14,   Method: Compositional matrix adjust.
 Identities = 34/127 (26%), Positives = 55/127 (43%), Gaps = 15/127 (11%)
 Frame = -1

Query: 413 GTYTCVASLKGGGXXXXXXXXXXXXXTVPPNLTVPQEKSPLVTREGDTIELQCQVTGKPK 472
           G YTCVA  +  G                P + +P +KS  + ++ +++ ++C+V G PK
Sbjct: 764 GMYTCVAEYEEAGVKSSISVDVPFYAH--PKV-LPFDKSKNLVQD-ESLVIECKVLGYPK 597

Query: 473 PIILWSRADKEVAMPDGT------MQMESYDGT------LRIVNVSREMSGMYRCQ---T 517
           P++ W   + E+   DG           SYDG       L I  V  + +G Y C    T
Sbjct: 596 PVVSWYMDNVEIV--DGADSRYSLKPANSYDGASIEGAKLVIEEVQFDDAGEYTCMSNYT 423

Query: 518 SQYNGFN 524
            ++  FN
Sbjct: 422 DKWPQFN 402

 Score = 34.3 bits (77), Expect = 0.23,   Method: Compositional matrix adjust.
 Identities = 29/109 (26%), Positives = 48/109 (44%), Gaps = 4/109 (3%)
 Frame = -1

Query: 482 KEVAMPDGTMQMESYDGTLRIVNVSREMSGMYRCQTSQYNGFNVKPREALVQLIVQYPPA 541
           K++ +      ++  +GTL I +  R  +GMY C  ++Y    VK       + V  P  
Sbjct: 851 KDIKVDGKERYIQHNNGTLEIQHPRRNFAGMYTC-VAEYEEAGVKS-----SISVDVPFY 690

Query: 542 VEPAFLEIRQG----QDRSVTMSCRVLRAYPIRVLTYEWRLGNKLLRTG 586
             P  L   +     QD S+ + C+VL  YP  V++  W + N  +  G
Sbjct: 689 AHPKVLPFDKSKNLVQDESLVIECKVL-GYPKPVVS--WYMDNVEIVDG 552

 Score = 32.7 bits (73), Expect = 0.72,   Method: Compositional matrix adjust.
 Identities = 33/136 (24%), Positives = 55/136 (40%), Gaps = 6/136 (4%)
 Frame = -1

Query: 291 NGGTLTIPAITSDDAGTYSCIANNNVGNPAKKSTNIIVRALKKGRFWITPD--PYHKDDN 348
           N GTL I     + AG Y+C+A        K S ++ V       F+  P   P+ K  N
Sbjct: 809 NNGTLEIQHPRRNFAGMYTCVAEYEEAG-VKSSISVDV------PFYAHPKVLPFDKSKN 651

Query: 349 IQIGREVKISCQVEAVPSEELTFSWFKNGRPLRSSERMVITQTDPDVSPGTT----NLDI 404
           +     + I C+V   P      SW+ +   +        +    +   G +     L I
Sbjct: 650 LVQDESLVIECKVLGYPKP--VVSWYMDNVEIVDGADSRYSLKPANSYDGASIEGAKLVI 477

Query: 405 IDLKFTDFGTYTCVAS 420
            +++F D G YTC+++
Sbjct: 476 EEVQFDDAGEYTCMSN 429

 Score = 32.3 bits (72), Expect = 0.88,   Method: Compositional matrix adjust.
 Identities = 15/43 (34%), Positives = 23/43 (53%)
 Frame = -1

Query: 290 LNGGTLTIPAITSDDAGTYSCIANNNVGNPAKKSTNIIVRALK 332
           + G  L I  +  DDAG Y+C++N     P   ST +I+  +K
Sbjct: 500 IEGAKLVIEEVQFDDAGEYTCMSNYTDKWPQFNSTQVILVRVK 372

 Score = 31.2 bits (69), Expect = 1.9,   Method: Compositional matrix adjust.
 Identities = 18/85 (21%), Positives = 35/85 (41%), Gaps = 12/85 (14%)
 Frame = -1

Query: 54  EGETLELTCLVTGHPRPQIRW------------TKTAGSASDRFQDSSVFNETLRITNIQ 101
           + E+L + C V G+P+P + W            ++ +   ++ +  +S+    L I  +Q
Sbjct: 644 QDESLVIECKVLGYPKPVVSWYMDNVEIVDGADSRYSLKPANSYDGASIEGAKLVIEEVQ 465

Query: 102 RHQGGRYYCKAENGLGSPAIKSIRV 126
               G Y C +      P   S +V
Sbjct: 464 FDDAGEYTCMSNYTDKWPQFNSTQV 390
>29881
          Length = 416

 Score = 33.9 bits (76), Expect = 0.29,   Method: Compositional matrix adjust.
 Identities = 27/83 (32%), Positives = 35/83 (42%)
 Frame = -3

Query: 281 FGTLPEKIVLNGGTLTIPAITSDDAGTYSCIANNNVGNPAKKSTNIIVRALKKGRFWITP 340
           F   P K +L    L +  +   DAG Y+C A N+ G  AK S  + V  +  GR    P
Sbjct: 330 FTQGPRKRMLVNNYLMVSNVVETDAGQYTCAARNSEGCFAKVSAYLNVETVGHGRECGKP 151

Query: 341 DPYHKDDNIQIGREVKISCQVEA 363
                  N   GR  +IS   EA
Sbjct: 150 RV-----NAFEGRSYRISSGREA 97
>36498
          Length = 478

 Score = 33.9 bits (76), Expect = 0.36,   Method: Compositional matrix adjust.
 Identities = 28/102 (27%), Positives = 42/102 (41%)
 Frame = +3

Query: 378 RPLRSSERMVITQTDPDVSPGTTNLDIIDLKFTDFGTYTCVASLKGGGXXXXXXXXXXXX 437
           RP RS    V+ + +P  +PGT  L    +   D G Y CVA  + G             
Sbjct: 174 RPRRSD---VLPEYEP--APGTAGLRFDPVSEGDAGRYVCVARNERG-ITEENVDLTVTR 335

Query: 438 XTVPPNLTVPQEKSPLVTREGDTIELQCQVTGKPKPIILWSR 479
             V P + +      ++  +G ++EL C   G   P+I W R
Sbjct: 336 TGVAPQVNIDGPGRQMLV-DGQSVELSCSARGLRNPLIRWRR 458

 Score = 30.8 bits (68), Expect = 2.7,   Method: Composition-based stats.
 Identities = 12/41 (29%), Positives = 21/41 (51%)
 Frame = +1

Query: 441 PPNLTVPQEKSPLVTREGDTIELQCQVTGKPKPIILWSRAD 481
           PP +TV    + +    GD ++++C   G P P + W R +
Sbjct: 49  PPTVTV-TPGTRITALVGDRVDIECVAEGDPTPTVFWRRIE 168

 Score = 25.4 bits (54), Expect(2) = 4.4,   Method: Composition-based stats.
 Identities = 17/55 (30%), Positives = 27/55 (49%), Gaps = 10/55 (18%)
 Frame = +1

Query: 239 TASPSIKLLVDDP--IVVNPGEAITLV--------CVTTGGEPTPSLTWVRSFGT 283
           T + +  L++  P  + V PG  IT +        CV  G +PTP++ W R  G+
Sbjct: 13  TVTLTASLVIQGPPTVTVTPGTRITALVGDRVDIECVAEG-DPTPTVFWRRIEGS 174

 Score = 23.1 bits (48), Expect(2) = 4.4,   Method: Compositional matrix adjust.
 Identities = 9/23 (39%), Positives = 12/23 (52%)
 Frame = +3

Query: 295 LTIPAITSDDAGTYSCIANNNVG 317
           L    ++  DAG Y C+A N  G
Sbjct: 231 LRFDPVSEGDAGRYVCVARNERG 299
>37675
          Length = 741

 Score = 31.6 bits (70), Expect = 1.6,   Method: Composition-based stats.
 Identities = 14/54 (25%), Positives = 26/54 (48%)
 Frame = +2

Query: 462 ELQCQVTGKPKPIILWSRADKEVAMPDGTMQMESYDGTLRIVNVSREMSGMYRC 515
           +++C   G PKP I W   +  ++       +ES +  L + N   + +G Y+C
Sbjct: 125 KMKCHAEGVPKPTISWLFNNVPISEDPQHYDLESANELLVVYNAGDQDTGAYKC 286
>32888
          Length = 418

 Score = 26.9 bits (58), Expect(2) = 1.7,   Method: Compositional matrix adjust.
 Identities = 10/23 (43%), Positives = 16/23 (69%)
 Frame = -2

Query: 295 LTIPAITSDDAGTYSCIANNNVG 317
           LTI ++ ++D G Y+CI +N  G
Sbjct: 114 LTIKSLGAEDKGNYTCIVSNTEG 46

 Score = 23.1 bits (48), Expect(2) = 1.7,   Method: Compositional matrix adjust.
 Identities = 8/29 (27%), Positives = 18/29 (62%)
 Frame = -3

Query: 252 IVVNPGEAITLVCVTTGGEPTPSLTWVRS 280
           ++ + G+ + L C   G +P+P +TW ++
Sbjct: 248 VLEDEGQTVRLDCRAKG-KPSPKVTWYKN 165

 Score = 31.2 bits (69), Expect = 1.9,   Method: Compositional matrix adjust.
 Identities = 12/43 (27%), Positives = 23/43 (53%)
 Frame = -3

Query: 453 LVTREGDTIELQCQVTGKPKPIILWSRADKEVAMPDGTMQMES 495
           ++  EG T+ L C+  GKP P + W +    +   D  ++++S
Sbjct: 248 VLEDEGQTVRLDCRAKGKPSPKVTWYKNGHIITNGDDRVEIKS 120

 Score = 30.0 bits (66), Expect = 4.8,   Method: Compositional matrix adjust.
 Identities = 12/32 (37%), Positives = 16/32 (50%)
 Frame = -3

Query: 47  ERVYTIREGETLELTCLVTGHPRPQIRWTKTA 78
           ER     EG+T+ L C   G P P++ W K  
Sbjct: 257 ERFVLEDEGQTVRLDCRAKGKPSPKVTWYKNG 162
>12764
          Length = 1055

 Score = 31.2 bits (69), Expect = 1.9,   Method: Compositional matrix adjust.
 Identities = 21/60 (35%), Positives = 28/60 (46%)
 Frame = +1

Query: 257 GEAITLVCVTTGGEPTPSLTWVRSFGTLPEKIVLNGGTLTIPAITSDDAGTYSCIANNNV 316
           G  + L C+T G  P P L   R  G      +  G TLT+  ++  D GTY+C   N V
Sbjct: 271 GLNLDLTCITQGN-PLPFLVEWRQEG--ENTTLATGNTLTLTNLSLSDTGTYTCTGYNTV 441
>35419
          Length = 623

 Score = 29.6 bits (65), Expect = 5.5,   Method: Composition-based stats.
 Identities = 19/77 (24%), Positives = 33/77 (42%), Gaps = 2/77 (2%)
 Frame = -2

Query: 346 DDNIQIGREVKISCQVEAVPSE--ELTFSWFKNGRPLRSSERMVITQTDPDVSPGTTNLD 403
           D  +  G + K +C     P E   L   W K+ + + + E+ + T    +      +L 
Sbjct: 550 DLEVNAGTDAKFTCSGTTDPEEVHMLKIKWMKDNKEISTVEQRMTTNIQDN------SLT 389

Query: 404 IIDLKFTDFGTYTCVAS 420
           I      D GTYTC+++
Sbjct: 388 ISGTIVRDSGTYTCIST 338
>18575
          Length = 531

 Score = 29.3 bits (64), Expect = 8.7,   Method: Compositional matrix adjust.
 Identities = 24/85 (28%), Positives = 37/85 (43%), Gaps = 11/85 (12%)
 Frame = -3

Query: 448 QEKSPL-------VTREGDTIELQCQVTGKPKPIILW---SRADK-EVAMPDGTMQMESY 496
           +E+SP+          EGD  E++C  T      + W   S A K ++   DG+ ++   
Sbjct: 529 EEESPISVTNPVTAVEEGDNAEIECTTT--VNETVEWYKGSNATKTQLVSQDGSSRVFFQ 356

Query: 497 DGTLRIVNVSREMSGMYRCQTSQYN 521
            G L + N     +G Y CQT   N
Sbjct: 355 SGVLTVNNAMLNDTGEYXCQTVSGN 281
>07294
          Length = 1339

 Score = 28.9 bits (63), Expect = 9.0,   Method: Compositional matrix adjust.
 Identities = 13/33 (39%), Positives = 22/33 (66%), Gaps = 2/33 (6%)
 Frame = +3

Query: 292 GGTLTIPAITS--DDAGTYSCIANNNVGNPAKK 322
           GGT+ +PAIT+  D  G     A++N+G+P ++
Sbjct: 279 GGTVDVPAITNFIDGGGNVLVAASSNIGDPLRE 377
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|58037409|ref|NP_083569.1| phosphohistidine
phosphatase [Mus musculus]
         (124 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

15171                                                                 114   7e-27
12422                                                                  91   2e-19
11926                                                                  28   0.98 
02020                                                                  28   1.3  
12627                                                                  27   2.4  
11413                                                                  26   5.3  
>15171
          Length = 624

 Score =  114 bits (286), Expect = 7e-27,   Method: Compositional matrix adjust.
 Identities = 59/117 (50%), Positives = 78/117 (66%)
 Frame = -2

Query: 8   IPDVDIDSDGVFKYVLIRVHLAEPSGDPAKECKEIVRGYKWAEYHADIYDKVSGELQRNG 67
           + D +ID +G FKY+LI+VH  E   D     K IVRG   AEYHADIYD+V   ++  G
Sbjct: 452 VXDAEID-EGTFKYILIKVHDXEKDEDY----KYIVRGTCEAEYHADIYDQVVDGIESKG 288

Query: 68  YDCECLGGGRISHQSQDRKIHVYGYSMGYGRAQHSVSTEKIKAKYPDYEVTWADDGY 124
            DCE +GGGRI H    + I +YGYSMG+GRA H+++   +K KY DY++TW +DGY
Sbjct: 287 LDCEVVGGGRIKHNPGKKTIVIYGYSMGFGRANHAITQAILKRKYTDYDITWNNDGY 117
>12422
          Length = 498

 Score = 90.5 bits (223), Expect = 2e-19,   Method: Compositional matrix adjust.
 Identities = 40/105 (38%), Positives = 62/105 (59%)
 Frame = -3

Query: 18  VFKYVLIRVHLAEPSGDPAKECKEIVRGYKWAEYHADIYDKVSGELQRNGYDCECLGGGR 77
            FKY+L +++     G+   + K IVRG   A +H+DIYD +  +L+ +G  CEC+GGG+
Sbjct: 496 TFKYILCKIY----EGNNTNDSKLIVRGSADAPFHSDIYDGLDADLEADGISCECVGGGK 329

Query: 78  ISHQSQDRKIHVYGYSMGYGRAQHSVSTEKIKAKYPDYEVTWADD 122
           + H   +R IHV+G S  YG A H+ +   +K  Y  Y + W D+
Sbjct: 328 VKHDPDERSIHVFGKSQAYGPANHATTASLLKEHYEGYNIEWTDE 194
>11926
          Length = 462

 Score = 28.1 bits (61), Expect = 0.98,   Method: Compositional matrix adjust.
 Identities = 15/52 (28%), Positives = 25/52 (48%)
 Frame = +3

Query: 41  EIVRGYKWAEYHADIYDKVSGELQRNGYDCECLGGGRISHQSQDRKIHVYGY 92
            IV G+ W EY + +  ++   L R G+ C C+      + +    +HVY Y
Sbjct: 321 RIVSGFWWCEYISALEYRLWPPLVRAGHKCVCV------YITACVCMHVYMY 458
>02020
          Length = 862

 Score = 27.7 bits (60), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 23/81 (28%), Positives = 33/81 (40%), Gaps = 5/81 (6%)
 Frame = +2

Query: 28  LAEPSGDPAKECKEIVRGYKWAEYHADIYDKVSGE-LQRNGYDCECL----GGGRISHQS 82
           L +P  +P K  K  + G  + E   +   K   E LQR G  C       G   ++H  
Sbjct: 20  LTKPLVNPHKMYKSDISGKCYNELKVETPIKKHNERLQRYGSRCSDAFHGEGSLSLTHTH 199

Query: 83  QDRKIHVYGYSMGYGRAQHSV 103
           +    H Y Y+   G  +HSV
Sbjct: 200 KHASTHTYMYAFNRGLDKHSV 262
>12627
          Length = 712

 Score = 26.6 bits (57), Expect = 2.4,   Method: Compositional matrix adjust.
 Identities = 11/26 (42%), Positives = 17/26 (65%)
 Frame = +3

Query: 69  DCECLGGGRISHQSQDRKIHVYGYSM 94
           D +  GGGRI HQ Q +++H  G ++
Sbjct: 576 DPDAPGGGRIGHQQQCQRVHPGGRAL 653
>11413
          Length = 501

 Score = 25.8 bits (55), Expect = 5.3,   Method: Compositional matrix adjust.
 Identities = 8/26 (30%), Positives = 15/26 (57%)
 Frame = -1

Query: 69  DCECLGGGRISHQSQDRKIHVYGYSM 94
           +C C+ G R       RK+++YG+ +
Sbjct: 249 ECACVAGDRFGFWGCGRKLYIYGFMI 172
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|115511052|ref|NP_034994.2| myosin Va [Mus musculus]
         (1853 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

25922                                                                 119   8e-27
01284                                                                  97   5e-20
30605                                                                  52   2e-06
33582                                                                  35   0.35 
15738                                                                  34   0.53 
18626                                                                  33   1.1  
28295                                                                  30   6.9  
>25922
          Length = 422

 Score =  119 bits (299), Expect = 8e-27,   Method: Compositional matrix adjust.
 Identities = 60/137 (43%), Positives = 86/137 (62%), Gaps = 1/137 (0%)
 Frame = -2

Query: 368 YEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFNWIVDHVNQALHSAV 427
           Y+ + H L HR +A   +     +S  +++ ARDAL K +Y+++F+W+V  +N ++    
Sbjct: 418 YDTLAHALMHRTVAVKGDMVTTDLSVSESSYARDALCKALYSRMFSWLVHRINDSIKVRG 239

Query: 428 KQHS-FIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKEQIPWTL 486
            Q +  +GVLDIYGFE FE NSFEQF INY NEKLQQ F     K EQEEY+KE I W  
Sbjct: 238 AQRTKVMGVLDIYGFEVFENNSFEQFIINYCNEKLQQIFIELTLKEEQEEYIKEGIEWIH 59

Query: 487 IDFYDNQPCINLIESKL 503
           +++++N     LIE  +
Sbjct: 58  VEYFNNAVICELIEKSV 8
>01284
          Length = 1603

 Score = 97.4 bits (241), Expect = 5e-20,   Method: Compositional matrix adjust.
 Identities = 59/203 (29%), Positives = 105/203 (51%), Gaps = 1/203 (0%)
 Frame = +2

Query: 634 TVGHQFRNSLHLLMETLNATTPHYVRCIKPNDFKFPFTFDEKRAVQQLRACGVLETIRIS 693
           +VG +FR  L +LM+ L +T  +++RCIKPN       F+    + QL+  G++  + + 
Sbjct: 17  SVGTKFRKQLLVLMDKLKSTGTNFIRCIKPNVKMVDHLFEGANILSQLQCAGMVSVLELM 196

Query: 694 AAGFPSRWTYQEFFSRYRVLMKQKDVLGDRKQTCKNVLEKLILDKDKYQFGKTKIFFRAG 753
             GFPSR  + E ++ Y+  +  +    D +  CK++ + L LD   ++FG TK+FFR G
Sbjct: 197 QQGFPSRTPFSELYNMYKKYLPPELSRLDPRLFCKSLFKALGLDDKDFKFGLTKVFFRPG 376

Query: 754 QVAYLEK-LRADKLRAACIRIQKTIRGWLLRKRYLCMQRAAITVQRYVRGYQARCYAKFL 812
           + A  ++ +++D    A   + K ++ WLL  R+   Q   ++V         +   K  
Sbjct: 377 KFAEFDQIMKSDPENLA--ELVKKVKKWLLCSRWKKAQWCTLSV--------IKLKNKIR 526

Query: 813 RRTKAATTIQKYWRMYVVRRRYK 835
            R +    IQK  RM++  R++K
Sbjct: 527 YRAEQFVMIQKSIRMWICVRKFK 595
>30605
          Length = 336

 Score = 52.0 bits (123), Expect = 2e-06,   Method: Composition-based stats.
 Identities = 35/111 (31%), Positives = 60/111 (54%), Gaps = 7/111 (6%)
 Frame = -3

Query: 299 VDDAKEMAHTRQACTLLGISESYQMGIFRILAGILHLGNVGFASRDSDS---CTIPPKHE 355
           +DD ++     +A T +G+S++ +M IF ++A +LHLGN+ F     D+   C +  + E
Sbjct: 334 LDDVRDFKVCDEAMTRMGVSDADKMAIFMLVAAVLHLGNIAFEDDHDDTKGGCKVLEEAE 155

Query: 356 -PLTIFCDLMGVDYEEMCHWLCHRKLATA--TETYIK-PISKLQATNARDA 402
             L     L+GVD  E+   L  R + +     + IK P+   +A++ARDA
Sbjct: 154 DSLATAAVLLGVDKMELRDSLTSRIMQSGGIKGSAIKVPLKPSEASSARDA 2
>33582
          Length = 1000

 Score = 34.7 bits (78), Expect = 0.35,   Method: Compositional matrix adjust.
 Identities = 17/44 (38%), Positives = 26/44 (59%), Gaps = 4/44 (9%)
 Frame = +3

Query: 766 LRAACIRIQKTIRGWLLRKRYLCMQRAAI----TVQRYVRGYQA 805
           L  A I IQ+ IRGWL+R+R+  ++R       T Q+ V+ Y+ 
Sbjct: 246 LHVAAIAIQRHIRGWLIRRRFYKLRRKVAWYGSTFQKMVKEYRG 377

 Score = 30.8 bits (68), Expect = 5.6,   Method: Compositional matrix adjust.
 Identities = 10/35 (28%), Positives = 21/35 (60%)
 Frame = +3

Query: 866 AVIIQKRVRGWLARTHYKRTMKAIVYLQCCFRRMM 900
           A+ IQ+ +RGWL R  + +  + + +    F++M+
Sbjct: 258 AIAIQRHIRGWLIRRRFYKLRRKVAWYGSTFQKMV 362
>15738
          Length = 500

 Score = 34.3 bits (77), Expect = 0.53,   Method: Composition-based stats.
 Identities = 20/64 (31%), Positives = 29/64 (45%)
 Frame = +1

Query: 553 FADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKMLPELFQDDEKAISPTSATSSGRTPL 612
              K ++   G L  NK+ VF  Q ++   + F  L   F D EK I     +   + PL
Sbjct: 259 LGSKSKHVSSGLL-TNKEAVFRTQTRI*A*NWFMHLTAWFYDTEKXIKSVLXSRINKNPL 435

Query: 613 TRVP 616
           TR+P
Sbjct: 436 TRIP 447
>18626
          Length = 401

 Score = 33.1 bits (74), Expect = 1.1,   Method: Composition-based stats.
 Identities = 20/62 (32%), Positives = 35/62 (56%)
 Frame = +3

Query: 966  NDVERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKSIEERADKYKQETDQLVS 1025
            N+++ L++  + A   T  + S Q E+ K   D E+ ++   + E+ ADK K E  +L+S
Sbjct: 147  NEIDTLEVFLKLAPADTTAISSAQIELKKENGDKEEVKAPADAGEDEADKEKAEV*ELLS 326

Query: 1026 NL 1027
            NL
Sbjct: 327  NL 332
>28295
          Length = 502

 Score = 30.4 bits (67), Expect = 6.9,   Method: Compositional matrix adjust.
 Identities = 23/70 (32%), Positives = 35/70 (50%), Gaps = 6/70 (8%)
 Frame = -3

Query: 792 AAITVQRYVRGYQARCYAKFLRRTK----AATTIQKYWRMYVVRRRY--KIRRAATIVIQ 845
           AA+ +Q+Y R  QAR     ++R K    A   I KY+  + VR+ Y  K RR A   + 
Sbjct: 437 AAVVIQKYARALQARALLGRMKREKLEQWAQGVIVKYFHGWQVRKVYKPKFRRIAGPKVA 258

Query: 846 SYLRGYLTRN 855
            +++  L R 
Sbjct: 257 RFIKTALKRR 228
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|29244132|ref|NP_808359.1| hypothetical protein
LOC232941 [Mus musculus]
         (404 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

15028                                                                 117   8e-27
29349                                                                  99   3e-21
06615                                                                  86   2e-17
14655                                                                  45   1e-07
>15028
          Length = 1779

 Score =  117 bits (293), Expect = 8e-27,   Method: Compositional matrix adjust.
 Identities = 88/274 (32%), Positives = 126/274 (45%), Gaps = 9/274 (3%)
 Frame = +3

Query: 55  TSGLRFGASAVQGWRARMEDAHCARLALPGLPSGWAFFAVLDXXXXXXXXXXXXXXLPGY 114
            S ++ G+S +QGWR  MEDAH   L LPG     +FF V D              L   
Sbjct: 177 NSQVKVGSSCMQGWRINMEDAHTHLLTLPGDKDA-SFFGVFDGHGGVKVAHYAGNHLHKK 353

Query: 115 VLGELGPAPQEPDGVRQALRSAFLQADAQL---SALWPRGDPGGSTAVALLVSPRFLYLA 171
           ++ +   +      V +A+R  FL  D  +    AL  + D  G+TAV +L+    ++  
Sbjct: 354 IVSQ---SSYSRGSVSEAVRQGFLSLDEDMMKDEAL--KDDLAGTTAVVVLLKEGKMFCG 518

Query: 172 HCGDSRALLSRSGSVAFCTEDXXXXXXXXXXXIHDAGGTVRRRRVEGSLAVSRALGDFAY 231
           + GDSRA+ S SG V   + D           I  AGG V   RV G+LA+SRALGDF +
Sbjct: 519 NVGDSRAVASVSGEVEQLSFDHKPSNEVESRRIVAAGGWVEFNRVNGNLALSRALGDFVF 698

Query: 232 KQAPGRPPELQLVSAEPEVAALARQDEDEFVLLASDGVWDALSGADLAGLVTSRXXXXXX 291
           K+   +  E Q+V+A P+V         EF++LA DG+WD L+  ++     +R      
Sbjct: 699 KKNEKKKAEEQIVTAYPDVIEKPLTPNHEFLVLACDGIWDVLTNQEVVDFTRTRIAQRME 878

Query: 292 XXXXXXXXXXX----XXXKGSL--DNMTCMVVCF 319
                              G L  DNMT ++VCF
Sbjct: 879 PDTICEELMMRCLAPDCQMGGLGCDNMTVILVCF 980
>29349
          Length = 479

 Score = 98.6 bits (244), Expect(2) = 3e-21,   Method: Compositional matrix adjust.
 Identities = 51/116 (43%), Positives = 65/116 (56%)
 Frame = -1

Query: 215 RVEGSLAVSRALGDFAYKQAPGRPPELQLVSAEPEVAALARQDEDEFVLLASDGVWDALS 274
           RV GSLAVSRALGD+ YK   G+ P  QLVS EPE+    R   DEF++LA DG+WD ++
Sbjct: 350 RVNGSLAVSRALGDYEYKNVEGKGPCEQLVSPEPEIFLEERSPGDEFMVLACDGIWDVMT 171

Query: 275 GADLAGLVTSRXXXXXXXXXXXXXXXXXXXXKGSLDNMTCMVVCFPGAPRPCEEAI 330
             +L   +TSR                    KGS DNM+ ++V F GAP   EE +
Sbjct: 170 NDELCAFITSRMKITSSLEEVCNQVVDTCLIKGSRDNMSIVLVAFEGAPSVSEEEV 3

 Score = 21.2 bits (43), Expect(2) = 3e-21,   Method: Compositional matrix adjust.
 Identities = 8/17 (47%), Positives = 11/17 (64%)
 Frame = -3

Query: 172 HCGDSRALLSRSGSVAF 188
           +CGDSRA  +   +V F
Sbjct: 477 NCGDSRAFCAGEANVPF 427
>06615
          Length = 1528

 Score = 85.9 bits (211), Expect = 2e-17,   Method: Compositional matrix adjust.
 Identities = 47/132 (35%), Positives = 72/132 (54%), Gaps = 1/132 (0%)
 Frame = +2

Query: 155 GSTAVALLVSPRFLYLAHCGDSRALLSRSGSVAFCTEDXXXXXXXXXXXIHDAGGTVRRR 214
           G TA  +L+    L +A+ GDSR++L R G     ++D           I  AGG V   
Sbjct: 11  GCTACVVLLRDNHLVVANAGDSRSVLCRGGVAVDLSDDHKPEDDPERLRIEGAGGRVTAD 190

Query: 215 -RVEGSLAVSRALGDFAYKQAPGRPPELQLVSAEPEVAALARQDEDEFVLLASDGVWDAL 273
            RV G L +SRA+GD  YK+    P E Q+++A P++  +A   ED+F++LA DG+W+++
Sbjct: 191 GRVNGGLNLSRAIGDHFYKRKEDLPAEKQMITALPDIQTVAVDPEDQFLILACDGIWNSM 370

Query: 274 SGADLAGLVTSR 285
           S  +    V  R
Sbjct: 371 SSQECVNFVAER 406
>14655
          Length = 507

 Score = 45.4 bits (106), Expect(2) = 1e-07,   Method: Compositional matrix adjust.
 Identities = 28/85 (32%), Positives = 44/85 (51%), Gaps = 4/85 (4%)
 Frame = +2

Query: 204 IHDAGGTVRRR----RVEGSLAVSRALGDFAYKQAPGRPPELQLVSAEPEVAALARQDED 259
           I + GG V       RV G+++VSRA+GD   K           + ++ + A   R   +
Sbjct: 167 IEELGGFVTNAFGVWRVNGTVSVSRAIGDVHEKP---------FLCSDADTACFERTGTE 319

Query: 260 EFVLLASDGVWDALSGADLAGLVTS 284
           ++++L  DGVWD LS +D+  LV S
Sbjct: 320 DYLVLGCDGVWDFLSPSDIPNLVHS 394

 Score = 28.1 bits (61), Expect(2) = 1e-07,   Method: Compositional matrix adjust.
 Identities = 14/33 (42%), Positives = 19/33 (57%)
 Frame = +1

Query: 155 GSTAVALLVSPRFLYLAHCGDSRALLSRSGSVA 187
           GST V +L+     Y++  GDS+  L R GSV 
Sbjct: 19  GSTGVNVLLRGDHCYVSWLGDSQVFLVRDGSVV 117
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|110626005|ref|NP_780344.2| eukaryotic translation
initiation factor 2B, subunit 3 gamma isoform 2 [Mus musculus]
         (445 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

00981                                                                 117   9e-27
21369                                                                 108   3e-24
15705                                                                  44   1e-04
01174                                                                  30   2.0  
32919                                                                  29   3.0  
22806                                                                  29   3.3  
38266                                                                  29   3.7  
>00981
          Length = 1528

 Score =  117 bits (293), Expect = 9e-27,   Method: Compositional matrix adjust.
 Identities = 74/271 (27%), Positives = 128/271 (47%), Gaps = 33/271 (12%)
 Frame = +2

Query: 172 NEADLDEELVIKGSILQKHPRIHFHTGLVDAHLYCLKKYVVDFLMEN---RSITSIRSEL 228
           N A+ D EL  K  I  K+P++   + + D HLY +K++++D+L  +     ++SIRS+L
Sbjct: 14  NNAEDDTELDPK--IFLKYPQVRVRSTMTDCHLYLMKRWILDYLATHPDCEKMSSIRSQL 187

Query: 229 IPYLVRKQFSSAS--------SQQRQXXXXXXXXXXXXXXXXIYSFIKKDDTLTLAPYDA 280
           +P+LV+KQF S           Q                   IY+F +    + ++    
Sbjct: 188 LPHLVKKQFPSEGRLKKSRVWQQTPTVDEAPVRLLPVNKDNDIYAFSEIPAAVDVSKNTL 367

Query: 281 CW--------------------NAFRGDKWEDLSRSQVRCYVHIMKEGLCSRVSTLGLYM 320
            W                    N F   +  D+    VRCY ++   G C R +    Y 
Sbjct: 368 DWAEAMSAGIMNVGHDGMDLDENTFHVTRDNDV----VRCYAYVQDSGFCVRTNNFSGYC 535

Query: 321 EANRQVPKLLSVLCPEE--SMIHSSAQIVNKHLIGADSLIGPDTQIGEKSSIKHSVIGSS 378
           EAN Q+ K+   + P+    ++H S ++     +G D  IG ++++GEK  +K SV+G++
Sbjct: 536 EANSQIAKIFPTIAPQNKADLVHPSVKVPRTTQMGPDCFIGDNSRVGEKMVMKKSVVGAN 715

Query: 379 CVIRDRTSITNCLLMNSVTVEEGYVSLCAFL 409
           CV+ D+  I+N +LM+ V V E  + + + L
Sbjct: 716 CVLHDKAKISNSILMDGVEVGESCLVMNSIL 808
>21369
          Length = 494

 Score =  108 bits (271), Expect = 3e-24,   Method: Compositional matrix adjust.
 Identities = 64/134 (47%), Positives = 85/134 (63%), Gaps = 8/134 (5%)
 Frame = -2

Query: 7   VMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVVTTK----DVQKA 62
           V+A G GSR+  LT   PK LLPVGN P ++YPL +LER GF E I+V+ +    +++  
Sbjct: 493 VLAAGMGSRVKHLTRYYPKALLPVGNFPAVYYPLAMLERHGFPEAIIVSPRSFEDEIRTT 314

Query: 63  LCAEFKMKMKLDIVCIPDEA--DMGTADSLRHIYPKL--KTDVLVLSCDLITDVALHEVV 118
           L  +  +KMKL    IPD    D GTA +L  +  K+   TDVLVLSCDLITD+ L+ V+
Sbjct: 313 LVDKCGIKMKLIFESIPDTQLEDHGTAKALCLVRSKIPDNTDVLVLSCDLITDLNLNHVI 134

Query: 119 DLFRAYDASLAMLM 132
            LF   DAS+ ML+
Sbjct: 133 SLFHKMDASITMLL 92
>15705
          Length = 2141

 Score = 43.9 bits (102), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 31/94 (32%), Positives = 47/94 (50%), Gaps = 1/94 (1%)
 Frame = +3

Query: 342 SSAQIVNKHLIGADSLIGPDTQIGEKSSIKHSVIGSSCVIRDRTSITNCLLMNSVTVEEG 401
           SSA++ N      + ++G  T I  K+ I+ SVIG +C+I    ++ NC L  SV +EEG
Sbjct: 39  SSAELKN------NVVVGKGTTIDAKTEIQSSVIGENCIIGANVTMRNCYLWGSVRIEEG 200

Query: 402 YV-SLCAFLSKASGSPRSLISPTQKSLLWDRKEG 434
            V S C      +    + + P    L W+ K G
Sbjct: 201 CVLSDCIVCDGVTVFANTTVQP-HSVLSWNVKVG 299
>01174
          Length = 3438

 Score = 30.0 bits (66), Expect = 2.0,   Method: Compositional matrix adjust.
 Identities = 17/45 (37%), Positives = 22/45 (48%), Gaps = 4/45 (8%)
 Frame = -1

Query: 296  SQVRCYVHIMKEGLCSRVSTLGLYMEANRQV----PKLLSVLCPE 336
            S   C V + + G  SRV  LGL +  NR      P  LS +CP+
Sbjct: 2919 SPTDCVVRMERLGKLSRVKKLGLSLNKNRSCSDSSPSTLSPICPD 2785
>32919
          Length = 308

 Score = 29.3 bits (64), Expect = 3.0,   Method: Composition-based stats.
 Identities = 18/29 (62%), Positives = 21/29 (72%)
 Frame = +3

Query: 46 VGFEEVIVVTTKDVQKALCAEFKMKMKLD 74
          VG  +VIV++TK VQKA CA FK   KLD
Sbjct: 3  VGQGKVIVISTKLVQKA-CAFFKQIKKLD 86
>22806
          Length = 784

 Score = 29.3 bits (64), Expect = 3.3,   Method: Compositional matrix adjust.
 Identities = 15/47 (31%), Positives = 27/47 (57%), Gaps = 4/47 (8%)
 Frame = -2

Query: 371 KHSVIGSSCVIR----DRTSITNCLLMNSVTVEEGYVSLCAFLSKAS 413
           KH+++ +  V R      T +T C+L NS  + + ++ +C F+S AS
Sbjct: 552 KHTLVTNLLVTRPAYXQNTLVTRCILPNSWGIFQRHMYMCTFMSDAS 412
>38266
          Length = 209

 Score = 29.3 bits (64), Expect = 3.7,   Method: Composition-based stats.
 Identities = 13/23 (56%), Positives = 14/23 (60%)
 Frame = +1

Query: 181 VIKGSILQKHPRIHFHTGLVDAH 203
           V K SIL+ H RIH H    DAH
Sbjct: 58  VFKTSILKMHARIHTHIKQADAH 126
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|46399202|ref|NP_963894.1| myosin Vb [Mus musculus]
         (1818 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

25922                                                                 119   9e-27
01284                                                                 100   6e-21
30605                                                                  49   2e-05
30506                                                                  34   0.55 
18005                                                                  31   4.2  
26093                                                                  30   8.3  
>25922
          Length = 422

 Score =  119 bits (299), Expect = 9e-27,   Method: Compositional matrix adjust.
 Identities = 60/134 (44%), Positives = 83/134 (61%), Gaps = 1/134 (0%)
 Frame = -2

Query: 369 HSQMEHWLCHRKLVTTSETYVKTMSLQQVVNARDALAKHIYAQLFSWIVEHINKALHTSL 428
           +  + H L HR +    +     +S+ +   ARDAL K +Y+++FSW+V  IN ++    
Sbjct: 418 YDTLAHALMHRTVAVKGDMVTTDLSVSESSYARDALCKALYSRMFSWLVHRINDSIKVRG 239

Query: 429 KQHS-FIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNSHVFKLEQEEYMKEQIPWTL 487
            Q +  +GVLDIYGFE FE NSFEQF INY NEKLQQ F     K EQEEY+KE I W  
Sbjct: 238 AQRTKVMGVLDIYGFEVFENNSFEQFIINYCNEKLQQIFIELTLKEEQEEYIKEGIEWIH 59

Query: 488 IDFYDNQPCIDLIE 501
           +++++N    +LIE
Sbjct: 58  VEYFNNAVICELIE 17
>01284
          Length = 1603

 Score =  100 bits (249), Expect = 6e-21,   Method: Compositional matrix adjust.
 Identities = 61/205 (29%), Positives = 111/205 (54%), Gaps = 2/205 (0%)
 Frame = +2

Query: 632 SVGYQFRTSLNLLMETLNATTPHYVRCIKPNDEKLPFHFDPKRAVQQLRACGVLETIRIS 691
           SVG +FR  L +LM+ L +T  +++RCIKPN + +   F+    + QL+  G++  + + 
Sbjct: 17  SVGTKFRKQLLVLMDKLKSTGTNFIRCIKPNVKMVDHLFEGANILSQLQCAGMVSVLELM 196

Query: 692 AAGYPSRWTYHDFFNRYRVLMKKRELTNTDKKNICKSVLESLIKDPDKFQFGRTKIFFRA 751
             G+PSR  + + +N Y+  +   EL+  D +  CKS+ ++L  D   F+FG TK+FFR 
Sbjct: 197 QQGFPSRTPFSELYNMYKKYLPP-ELSRLDPRLFCKSLFKALGLDDKDFKFGLTKVFFRP 373

Query: 752 GQVAYLEK-LRADKFREATIMIQKSVRGWLQRVKYRRLRAATLSLQRFCRGYLARRLAEH 810
           G+ A  ++ +++D    A ++  K V+ WL   ++++ +  TLS+          +L   
Sbjct: 374 GKFAEFDQIMKSDPENLAELV--KKVKKWLLCSRWKKAQWCTLSVI---------KLKNK 520

Query: 811 LR-RTRAAIVFQKQYRMLKARRAYR 834
           +R R    ++ QK  RM    R ++
Sbjct: 521 IRYRAEQFVMIQKSIRMWICVRKFK 595
>30605
          Length = 336

 Score = 48.9 bits (115), Expect = 2e-05,   Method: Composition-based stats.
 Identities = 23/84 (27%), Positives = 49/84 (58%), Gaps = 3/84 (3%)
 Frame = -3

Query: 299 VNDADDFEKTRQALTLLGVRDSHQISIFKIIASILHLGSVEIQSERD---GDSCSISPQD 355
           ++D  DF+   +A+T +GV D+ +++IF ++A++LHLG++  + + D   G    +   +
Sbjct: 334 LDDVRDFKVCDEAMTRMGVSDADKMAIFMLVAAVLHLGNIAFEDDHDDTKGGCKVLEEAE 155

Query: 356 EHLSNFCSLLGIEHSQMEHWLCHR 379
           + L+    LLG++  ++   L  R
Sbjct: 154 DSLATAAVLLGVDKMELRDSLTSR 83
>30506
          Length = 1317

 Score = 33.9 bits (76), Expect = 0.55,   Method: Compositional matrix adjust.
 Identities = 17/34 (50%), Positives = 23/34 (67%)
 Frame = -3

Query: 882 LRERDAAIVIQCAFRRLKARQELKALKIEARSAE 915
           ++E DAAI IQ  FR    RQE+K+ K E+ SA+
Sbjct: 436 MKEEDAAIKIQAGFRGYIDRQEIKSRKSESGSAK 335
>18005
          Length = 564

 Score = 31.2 bits (69), Expect = 4.2,   Method: Compositional matrix adjust.
 Identities = 21/57 (36%), Positives = 30/57 (52%)
 Frame = +1

Query: 966  ELAHYQQNQEADTSLQLQEEVQSLRTELQKAHSERRVLEDAHNKENGELRKRVADLE 1022
            EL+H Q   EA   L  +E++ +L  E+++  +    LED    E G LR  V DLE
Sbjct: 49   ELSHLQMKAEAGEDLFSEEDLATLDAEIEQIRAANEGLED----EVGGLRMEVTDLE 207
>26093
          Length = 1075

 Score = 30.0 bits (66), Expect = 8.3,   Method: Compositional matrix adjust.
 Identities = 13/28 (46%), Positives = 18/28 (64%)
 Frame = -1

Query: 887 AAIVIQCAFRRLKARQELKALKIEARSA 914
           AAI IQ  F+ LKAR+E+ A K +  + 
Sbjct: 520 AAIKIQAGFKGLKARKEINANKTDGEAG 437
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|158937298|ref|NP_080355.2| inhibitor of kappa light
polypeptide enhancer in B-cells, kinase complex-associated protein
[Mus musculus]
         (1333 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

27066                                                                 119   1e-26
35192                                                                  86   1e-16
18564                                                                  65   2e-10
12415                                                                  33   0.52 
04981                                                                  33   0.90 
21045                                                                  32   2.5  
01558                                                                  31   3.7  
28153                                                                  30   7.1  
>27066
          Length = 432

 Score =  119 bits (297), Expect = 1e-26,   Method: Compositional matrix adjust.
 Identities = 65/143 (45%), Positives = 85/143 (59%)
 Frame = +2

Query: 289 VNDLLWNADSSVLAIWLEDLPKEDSSTLKSYVQLWTVGNYHWYLKQSLPFSTTGKNQIVS 348
           V ++LWN +SSVL +W + +  + ++   S+VQLWT  NYHW +KQ+L F      ++  
Sbjct: 5   VMEVLWNLESSVLCVWCQAVNTDTATRSDSWVQLWTCSNYHWSMKQTLTFDHL-HGKVSG 181

Query: 349 LLWDPVTPCRLHVLCTGWRYLCCDWHWTTDRSSGNSANDLANVAVIDGNRVLVTVFRQTV 408
           LLWDP    RLH+  T   Y    W WTT+ S G ++ D A V VIDGN V VT  RQ V
Sbjct: 182 LLWDPEQAFRLHLTTTMGHYFQYTWTWTTNHSLGMTSCDPAAVYVIDGNSVKVTPMRQMV 361

Query: 409 VPPPMCTYRLLIPHPVNQVIFSA 431
           VPPPM  Y+L +P    QVI  A
Sbjct: 362 VPPPMSAYQLPLPSSAAQVISPA 430
>35192
          Length = 328

 Score = 85.9 bits (211), Expect = 1e-16,   Method: Composition-based stats.
 Identities = 40/102 (39%), Positives = 68/102 (66%)
 Frame = +3

Query: 975  ALKLYRPDSPQYQAVSMAYGEHLMQEHLYEPAGLVFARCGAQEKALEAFLACGSWQQALC 1034
            +LKL+  D+ Q++ +S  YG++L +++ ++ AG++F R    + A EAF+A  +W+QALC
Sbjct: 21   SLKLFAVDTSQFKTLSKEYGQYLREKNRHDEAGIMFIRGQHWQLAQEAFVAALNWRQALC 200

Query: 1035 VAAQLQMSKDKVAGLARTLAGKLVEQRKHSEAATVLEQYAQD 1076
            +AA ++   +  A LAR+LA +L    +H EAA V EQ+ +D
Sbjct: 201  MAAHMKTDDNTTADLARSLADRLKASMRHGEAAVVYEQHVKD 326
>18564
          Length = 769

 Score = 64.7 bits (156), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 38/114 (33%), Positives = 62/114 (54%), Gaps = 6/114 (5%)
 Frame = +2

Query: 1226 VVQSVEKLKDEVRAILKVLFLFEFEEQAKELQRAFESTLQLMERAVPEIWTPAGQQSSTT 1285
            ++ S++ ++DEV  +L VL  F      ++LQR +E  L  ++  VP++W    Q+S+T 
Sbjct: 146  IIASIDSMRDEVNTLLHVLTQFHQVALGEDLQRQYEGCLGRVQTIVPQVWXQE-QESNTD 322

Query: 1286 PVLGPSSTANSITASYQQQKTCVPALDAG------VYMPPKMDPRSQWKLSLLE 1333
             VLGP  TAN+I  + QQ  T    LD G      + + P +    +WKL +L+
Sbjct: 323  TVLGPGMTANAIAEAMQQGXT----LDGGEKTDPVLKVAPXLKKDVRWKLHMLQ 472
>12415
          Length = 451

 Score = 33.5 bits (75), Expect = 0.52,   Method: Compositional matrix adjust.
 Identities = 24/89 (26%), Positives = 40/89 (44%), Gaps = 2/89 (2%)
 Frame = +2

Query: 853 EIVLQKVQELQGNLPFDPESVSVEEALKYLLLLVDVNELFNHSLGTYDFNLVLMVAEKSQ 912
           ++V +K+Q  + +LP  P S      L +LL++V V                  V+ KSQ
Sbjct: 38  KVVTEKIQNNRHSLPLSPAS---HNTLPWLLIMVSVPR---------------KVSSKSQ 163

Query: 913 KDPKEYLPFLNTLKKMETNY--QRFTIDK 939
           K+PK    F  + K    N+  + FT+ +
Sbjct: 164 KNPKHTTIFFRSPKHTHKNHR*ENFTLHR 250
>04981
          Length = 1159

 Score = 32.7 bits (73), Expect = 0.90,   Method: Compositional matrix adjust.
 Identities = 18/54 (33%), Positives = 30/54 (55%), Gaps = 1/54 (1%)
 Frame = +2

Query: 380 SSGNSANDLANVAVIDGNRVLV-TVFRQTVVPPPMCTYRLLIPHPVNQVIFSAH 432
           SS ++   L++ A++  + V   T +   VVPPP+ T+RL    P N  ++ AH
Sbjct: 542 SSXSACTGLSSSALLQSDSVFCRTRWVAVVVPPPLGTHRLQAGDPGNAHVYVAH 703
>21045
          Length = 627

 Score = 31.6 bits (70), Expect = 2.5,   Method: Composition-based stats.
 Identities = 12/40 (30%), Positives = 25/40 (62%)
 Frame = -1

Query: 715 GNLEVVHHRALVLAQIRKWLDKLMFKEAFECMRKLRINLN 754
           GN   + HR ++L  IRKW+ + +   +  C+R++R+ ++
Sbjct: 459 GNKF*IRHRHVIL-MIRKWMRRFIIIFSLNCLRQMRVRIS 343
>01558
          Length = 2767

 Score = 30.8 bits (68), Expect = 3.7,   Method: Composition-based stats.
 Identities = 11/17 (64%), Positives = 11/17 (64%)
 Frame = +3

Query: 364  TGWRYLCCDWHWTTDRS 380
            T WR LC DW WT D S
Sbjct: 1140 TAWRPLCSDWMWTLDSS 1190
>28153
          Length = 871

 Score = 30.0 bits (66), Expect = 7.1,   Method: Composition-based stats.
 Identities = 16/46 (34%), Positives = 20/46 (43%)
 Frame = -1

Query: 1027 GSWQQALCVAAQLQMSKDKVAGLARTLAGKLVEQRKHSEAATVLEQ 1072
            G  Q A+C       S DKV   AR   G+ V    HS++  V  Q
Sbjct: 580  GELQNAVCYVLSFWYSPDKVGAWARPYRGEEVTTNNHSQSVLVRVQ 443
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|26986567|ref|NP_758470.1| lysophosphatidylglycerol
acyltransferase 1 isoform 2 [Mus musculus]
         (370 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

27346                                                                 116   1e-26
27546                                                                  28   7.3  
>27346
          Length = 790

 Score =  116 bits (291), Expect = 1e-26,   Method: Compositional matrix adjust.
 Identities = 74/200 (37%), Positives = 103/200 (51%), Gaps = 11/200 (5%)
 Frame = +1

Query: 182 FP-EGGFLRKRRETSQAFAKKNNLPFLTHVTLPRFGATNIILKALVARQENGSPAGGDAR 240
           FP +GGFL KR E+SQ +A+K   P L +VTLPR GA  +I+  + + ++  +   G   
Sbjct: 76  FPRKGGFLHKRLESSQNYARKYGYPVLNNVTLPRIGALTLIIDTVGSVEQGETLDNGYND 255

Query: 241 G---LECKSRGLQWIIDTTIAY--PKAEPIDIQTWILGYRKPTVTHVHYRIFPIGDVPLE 295
           G          L+WI+D TI Y   + EP D+    +GYR     HVHYR +P+ +VP +
Sbjct: 256 GKTDTHDPDHPLKWIVDMTIGYRNKEGEPPDMLGMCVGYRVKQDVHVHYRAYPLSEVPRD 435

Query: 296 TEDLTSWLYQRFIEKEDLLSHFYKTGAFPPPQGQKEAVCREMTLSNM---W--IFLIQSF 350
            E+   W Y R+ EK+ LL +F   G FPP    ++ V  EM    +   W  I LIQ+F
Sbjct: 436 XEEQLKWFYDRYAEKDTLLDYFNTHGHFPP--KNEDRVLPEMPEQRVVYDWVKIVLIQAF 609

Query: 351 AFLSGYLWYHIIQYFYHCLF 370
              S Y  Y  I     CL 
Sbjct: 610 YLGSCYFHYTCIARPLMCLL 669

 Score = 37.4 bits (85), Expect = 0.010,   Method: Compositional matrix adjust.
 Identities = 22/48 (45%), Positives = 30/48 (62%), Gaps = 1/48 (2%)
 Frame = +3

Query: 158 QQLLVLKKHLEHNYRSRDRKWIVLF-PEGGFLRKRRETSQAFAKKNNL 204
           QQ ++LK HL+  Y  + RKWIVLF P+GG       +SQA  K++ L
Sbjct: 3   QQGIMLKNHLKEIYLPQQRKWIVLFSPKGGL------SSQATGKQSKL 128
>27546
          Length = 426

 Score = 27.7 bits (60), Expect = 7.3,   Method: Compositional matrix adjust.
 Identities = 11/28 (39%), Positives = 17/28 (60%)
 Frame = -1

Query: 302 WLYQRFIEKEDLLSHFYKTGAFPPPQGQ 329
           +++ R+ EK D+LSH  KTG     Q +
Sbjct: 252 FIFMRYAEKGDMLSHIKKTGPIDEAQTK 169
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|112363107|ref|NP_032717.2| neurofilament 3, medium
[Mus musculus]
         (848 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

11243                                                                 117   2e-26
02016                                                                  79   1e-14
26996                                                                  53   5e-07
22014                                                                  48   2e-05
19956                                                                  33   0.40 
30620                                                                  32   1.4  
>11243
          Length = 828

 Score =  117 bits (293), Expect = 2e-26,   Method: Compositional matrix adjust.
 Identities = 78/241 (32%), Positives = 138/241 (57%)
 Frame = -2

Query: 198 EAAIRALRKDIEESSMVKVELDKKVQSLQDEVAFLRSNHEEEVADLLAQIQASHITVERK 257
           E+ I  LR+ ++E ++ K +L+ +++SL++E+ +L+ NHEEE+A + +  +  ++ V+  
Sbjct: 824 ESDIVGLRRVLDELTLNKTDLELEIESLKEELIYLKKNHEEELAVVRSSARG-NVDVQVD 648

Query: 258 DYLKTDISTALKEIRSQLECHSDQNMHQAEEWFKCRYAKLTEAAEQNKEAIRSAKEEIAE 317
                D++  + ++RSQ E   ++N  + E  +K +   L      N  A++++K  I +
Sbjct: 647 SAPPVDLAQIMXDVRSQYESMMEKNRQELEACYKGQSENLNHEVATNTAALQTSKTAITD 468

Query: 318 YRRQLQSKSIELESVRGTKESLERQLSDIEERHNHDLSSYQDTIQQLENELRGTKWEMAR 377
            +R +QS  IEL+S+   K +LE  L++ E ++   L+  Q  I Q+E EL+  + +   
Sbjct: 467 LKRTIQSLEIELQSLLSMKGALEGTLAETEAQYGAQLNHLQAMITQVEMELQNLRSDADH 288

Query: 378 HLREYQDLLNVKMALDIEIAAYRKLLEGEETRFSTFSGSITGPLYTHRQPSVTISSKIQK 437
              EY+ LL+ K  L++EIA YR+LLEGE+TRFS           T  Q +VTI SK Q 
Sbjct: 287 QSLEYKRLLDAKTRLEMEIATYRRLLEGEDTRFSQ----------TETQKAVTIVSKEQS 138

Query: 438 T 438
           +
Sbjct: 137 S 135
>02016
          Length = 3061

 Score = 78.6 bits (192), Expect = 1e-14,   Method: Compositional matrix adjust.
 Identities = 59/210 (28%), Positives = 115/210 (54%), Gaps = 2/210 (0%)
 Frame = +3

Query: 204 LRKDIEESSMVKVELDKKVQSLQDEVAFLRSNHEEEVAD--LLAQIQASHITVERKDYLK 261
           L+K +EE ++++V+L+ ++QSL++E+ F    +E+E+ +  +   ++   +    +   +
Sbjct: 159 LKKQLEEETLLRVDLENRLQSLKEEINFKSQVYEQELEESRVRTTVEIEQVDGRLEHEYE 338

Query: 262 TDISTALKEIRSQLECHSDQNMHQAEEWFKCRYAKLTEAAEQNKEAIRSAKEEIAEYRRQ 321
             +  AL+EIR+Q E        + E  ++ + A L   A ++  A  SA EE+   R++
Sbjct: 339 QRLLEALREIRAQHESDLQTVRVELETLYENKIADLKAQANRSNSASGSAWEELRITRKR 518

Query: 322 LQSKSIELESVRGTKESLERQLSDIEERHNHDLSSYQDTIQQLENELRGTKWEMARHLRE 381
                 EL  ++      E ++SD+E +   +   ++  + Q ++EL   +  +   ++E
Sbjct: 519 ADDLGAELAKLKAETAGFELRISDLESQLAREREEFRLRLAQKDDELAELRLTLEEQMQE 698

Query: 382 YQDLLNVKMALDIEIAAYRKLLEGEETRFS 411
           Y DLL++K+ LD EI AYRKLLE EE+R +
Sbjct: 699 YSDLLDIKIRLDREIDAYRKLLESEESRLN 788
>26996
          Length = 386

 Score = 52.8 bits (125), Expect = 5e-07,   Method: Compositional matrix adjust.
 Identities = 27/80 (33%), Positives = 50/80 (62%), Gaps = 3/80 (3%)
 Frame = -1

Query: 95  SRSNEKEQLQGLNDRFAGYIEKVHYLEQQNKEIEAEIQA---LRQKQASHAQLGDAYDQE 151
           +R  E+E LQGLNDR A YI++V +LE +N  +  ++Q+   + +++ S  +  + Y+ E
Sbjct: 236 TRQQEQESLQGLNDRLANYIDRVRFLEAENSRLSTQVQSTEEIVKREVSSVK--NLYETE 63

Query: 152 IRELRATLEMVNHEKAQVQL 171
           + + R  L+    EKA++Q+
Sbjct: 62  LADARRLLDDTAREKARIQI 3
>22014
          Length = 353

 Score = 47.8 bits (112), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 24/49 (48%), Positives = 35/49 (71%)
 Frame = -1

Query: 361 IQQLENELRGTKWEMARHLREYQDLLNVKMALDIEIAAYRKLLEGEETR 409
           + QL+ E+   + EM   L E Q L++ K++L++EIAAYRKLLE EE+R
Sbjct: 212 VNQLKEEMNKLRAEMEAMLVELQTLMDAKLSLELEIAAYRKLLETEESR 66
>19956
          Length = 536

 Score = 33.5 bits (75), Expect = 0.40,   Method: Compositional matrix adjust.
 Identities = 41/166 (24%), Positives = 78/166 (46%), Gaps = 43/166 (25%)
 Frame = -3

Query: 118 HYLEQQNKEIEAEIQALRQK-QASHAQLGDAYDQEIRELRATLEMVNHEKAQVQLDSDHL 176
            YLE +N  +  +IQ+  +  +   + + + Y+ E+ + R  L+    EKA+VQ+++   
Sbjct: 534 RYLEAENNRLSTQIQSTEETVKREVSSVKNLYENELSDARKVLDETAKEKARVQIEASTF 355

Query: 177 ----EEDIHRLKERFEE-----------EARLRD------DTEAAIRALRKD-------- 207
               E+ + + K+R  E           E +L D      D +AA   L+KD        
Sbjct: 354 KTKYEDMLAKYKQRDREASGAEQRVENLEVQLADLSAKLNDADAARARLQKDMSGLRSQL 175

Query: 208 -------------IEESSMVKVELDKKVQSLQDEVAFLRSNHEEEV 240
                        IEE ++++V+L+ +VQSL++E+ F    +E+E+
Sbjct: 174 SSQEQQLGTAKQQIEEETLLRVDLENRVQSLKEELQFKAQLYEQEL 37
>30620
          Length = 413

 Score = 31.6 bits (70), Expect = 1.4,   Method: Compositional matrix adjust.
 Identities = 20/80 (25%), Positives = 38/80 (47%)
 Frame = +2

Query: 369 RGTKWEMARHLREYQDLLNVKMALDIEIAAYRKLLEGEETRFSTFSGSITGPLYTHRQPS 428
           R   W++A  +R   D+L+V+   D+  A  RKL+    + F    G +T    T     
Sbjct: 8   RNFTWDVASGVRNGVDILDVRWGQDMHGATTRKLINESHSVFVMLQGQVTSLTGTALYNQ 187

Query: 429 VTISSKIQKTKVEAPKLKVQ 448
           +  +S+  ++  +A  L++Q
Sbjct: 188 LKEASRQYRSIAKACSLELQ 247
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|225543191|ref|NP_742120.2| ciliary rootlet
coiled-coil isoform 1 [Mus musculus]
         (2009 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

35266                                                                 119   2e-26
18417                                                                  77   7e-14
26041                                                                  61   3e-11
29118                                                                  60   6e-09
27823                                                                  54   5e-07
01576                                                                  50   1e-05
27352                                                                  39   0.022
16228                                                                  30   8.4  
>35266
          Length = 601

 Score =  119 bits (297), Expect = 2e-26,   Method: Compositional matrix adjust.
 Identities = 75/192 (39%), Positives = 106/192 (55%)
 Frame = +1

Query: 243 EQLDQANLANQALSEDIRKVTSDWTRSCKELEQREAVWRREEESFNTYFSSEHSRLLRLW 302
           +QLD AN  NQ L+ DI K+T DW R+ +ELE +EA WR EE+SFN YFS+EH RLL LW
Sbjct: 1   DQLDHANEVNQQLTSDIHKLTQDWQRAREELEAKEAEWRDEEKSFNEYFSAEHGRLLTLW 180

Query: 303 RQVMGLRRQASEVKMGTERDLLQLGGELVRTSRAVQELGLGLSASLHRAESXXXXXXXXX 362
           R V+  RRQ SE+K  TERDL  +  ++ + SR++    L L A++   ++         
Sbjct: 181 RAVVAFRRQFSEMKTATERDLSHVRADVTKASRSMHSACLNLGANMRSVDTQGQVSLDRE 360

Query: 363 XXXXXXXXXXXXXXXXXXXDLAQLQVQSDLDKADLSARVTELALSVEHLQNQNSEKDQVN 422
                                 QLQ +S  ++++L ARV EL +  E L+ Q  E+D+  
Sbjct: 361 RSERMSLEN-------------QLQSRS-REQSELQARVNELTMLNEKLKIQLEERDKSI 498

Query: 423 RTLSDKLEALES 434
            TL   L ++ES
Sbjct: 499 STLQKNLSSIES 534
>18417
          Length = 468

 Score = 77.0 bits (188), Expect = 7e-14,   Method: Compositional matrix adjust.
 Identities = 40/73 (54%), Positives = 57/73 (78%)
 Frame = +1

Query: 700 LQTEKAEVAEALTKAEAGRAQLELSLTKLRAEEASLRDSLSKMSALNESLAQDKLELNRL 759
           L+ +K EV EAL++AE  +A+LE+ + K++ EEASLRDSL K+ +LNE L QDK ELN++
Sbjct: 1   LEGQKIEVGEALSRAEMCKAELEVEMNKVKTEEASLRDSLLKLRSLNEGLGQDKQELNKI 180

Query: 760 IAQLEEEKVALLG 772
           I  LE+EK+ L+G
Sbjct: 181 ITLLEQEKLNLIG 219
>26041
          Length = 418

 Score = 61.2 bits (147), Expect(2) = 3e-11,   Method: Compositional matrix adjust.
 Identities = 42/119 (35%), Positives = 62/119 (52%), Gaps = 22/119 (18%)
 Frame = -3

Query: 136 PRGLVRQSVELRRQLQEEQSSYRRKLXXXXXXXXXXXXXXXXXXXKILQYKKQCSELEKQ 195
           P  L +Q++ELRR+L+EE S+Y+RKL                   K+LQYK++C +LE  
Sbjct: 347 PPSLCQQNLELRRKLEEEHSNYKRKLQSYQDGQQRQAQLVQKLQAKLLQYKQKCLDLEHA 168

Query: 196 LMDRSTELEQQRLRDT----------------------EHSQDLDSALLRLEEEQQRSA 232
             +R ++L    LR T                      EH+ DL++AL++LEEEQQRS+
Sbjct: 167 TKERDSQL----LRSTYKVHTSSERLESSESRLKRVEMEHATDLETALIKLEEEQQRSS 3

 Score = 26.9 bits (58), Expect(2) = 3e-11,   Method: Compositional matrix adjust.
 Identities = 10/18 (55%), Positives = 16/18 (88%)
 Frame = -2

Query: 112 KYNAVNERLEQAVRLETG 129
           KYNA++ERLEQ+++  +G
Sbjct: 417 KYNALSERLEQSLKGGSG 364
>29118
          Length = 335

 Score = 60.5 bits (145), Expect = 6e-09,   Method: Compositional matrix adjust.
 Identities = 33/73 (45%), Positives = 51/73 (69%)
 Frame = +3

Query: 1852 AEKRDLERSALQFDKDRVALRKTLDKVEREKLRSHEDTLRLNAERGRLDRTLTGAELDLA 1911
            +EK + E+S+++ +KD+ ALRKTLDKVEREK+R+ E   +   +R   DR +   E D A
Sbjct: 3    SEKNEAEKSSVRLEKDKNALRKTLDKVEREKIRTEEIATKTLYDRSNFDRVVQRLEEDNA 182

Query: 1912 EAQQQIQHLEAQV 1924
            E Q Q+QH+++Q+
Sbjct: 183  ELQLQLQHMQSQL 221
>27823
          Length = 537

 Score = 54.3 bits (129), Expect = 5e-07,   Method: Compositional matrix adjust.
 Identities = 36/102 (35%), Positives = 54/102 (52%), Gaps = 8/102 (7%)
 Frame = -3

Query: 94  RVEDLLAQSRAERDELAIKYNAVNERLEQAVRL--------ETGELEAQEPRGLVRQSVE 145
           R+ED+L+ SRAERDE+ IKY A++ER+EQ            +   + +     L +Q++E
Sbjct: 313 RMEDMLSNSRAERDEIGIKYXALSERVEQRTTTXTGLGLGDDASSMCSSSSGSLAQQNLE 134

Query: 146 LRRQLQEEQSSYRRKLXXXXXXXXXXXXXXXXXXXKILQYKK 187
           LR +L+EE S Y+RKL                   K+ QYK+
Sbjct: 133 LRHRLEEEHSLYKRKLLSYQEGQHRQAQLVQKLQSKLHQYKR 8
>01576
          Length = 2769

 Score = 49.7 bits (117), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 24/32 (75%), Positives = 27/32 (84%)
 Frame = -1

Query: 1964 LEARERAHRQRVSGLEEQVSTLKAQLHQELRR 1995
            LEARER HRQ++ GLEEQ+ TLK QL QELRR
Sbjct: 2766 LEARERTHRQKIKGLEEQIHTLKDQLSQELRR 2671
>27352
          Length = 377

 Score = 38.9 bits (89), Expect = 0.022,   Method: Compositional matrix adjust.
 Identities = 30/97 (30%), Positives = 47/97 (48%), Gaps = 8/97 (8%)
 Frame = -1

Query: 1086 LAAISLEMERQKRDAQSRQEQDRNTLNALTSELRDLRAQLEEATAAHAQTVKELEERTGN 1145
            L+  ++  +R K ++Q+R E DRN +  L +ELRDL  + +EA   H + V        N
Sbjct: 365  LSDANVRYDRLKLESQTRAEADRNNILDLQAELRDLHQRFQEAVEGHEREV-------AN 207

Query: 1146 LGRQREACMREAEELRTQ--------LRVLEDTRDGL 1174
            L  Q     R  E LR           +++E+TRD +
Sbjct: 206  LNNQPRMSWRARERLRWPRSWN*RLSSKMVEETRDAI 96
>16228
          Length = 419

 Score = 30.4 bits (67), Expect = 8.4,   Method: Composition-based stats.
 Identities = 13/40 (32%), Positives = 23/40 (57%)
 Frame = +2

Query: 253 QALSEDIRKVTSDWTRSCKELEQREAVWRREEESFNTYFS 292
           Q LS D++K+TS    SC++      VW  ++ +F  ++S
Sbjct: 167 QNLSHDLQKLTSSSMLSCRQQSSGGLVWTSDQITFGHHYS 286
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31982755|ref|NP_035831.2| vimentin [Mus musculus]
         (466 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

11243                                                                 116   2e-26
02016                                                                  91   1e-18
26996                                                                  60   2e-09
22014                                                                  52   4e-07
19956                                                                  37   0.016
>11243
          Length = 828

 Score =  116 bits (290), Expect = 2e-26,   Method: Compositional matrix adjust.
 Identities = 76/215 (35%), Positives = 119/215 (55%), Gaps = 1/215 (0%)
 Frame = -2

Query: 199 AESTLQSFRQDVDNASLARLDLERKVESLQEEIAFLKKLHDXXXXXXXXXXXXXXXXXDV 258
           AES +   R+ +D  +L + DLE ++ESL+EE+ +LKK H+                  V
Sbjct: 827 AESDIVGLRRVLDELTLNKTDLELEIESLKEELIYLKKNHEEELAVVRSSARGNVDVQ-V 651

Query: 259 DVSKP-DLTAALRDVRQQYESVAAKNLQEAEEWYKSKFADLSEAANRNNDALRQAKQESN 317
           D + P DL   + DVR QYES+  KN QE E  YK +  +L+     N  AL+ +K    
Sbjct: 650 DSAPPVDLAQIMXDVRSQYESMMEKNRQELEACYKGQSENLNHEVATNTAALQTSKTAIT 471

Query: 318 EYRRQVQSLTCEVDALKGTNESLERQMREMEENFALEAANYQDTIGRLQDEIQNMKEEMA 377
           + +R +QSL  E+ +L     +LE  + E E  +  +  + Q  I +++ E+QN++ +  
Sbjct: 470 DLKRTIQSLEIELQSLLSMKGALEGTLAETEAQYGAQLNHLQAMITQVEMELQNLRSDAD 291

Query: 378 RHLREYQDLLNVKMALDIEIATYRKLLEGEESRIS 412
               EY+ LL+ K  L++EIATYR+LLEGE++R S
Sbjct: 290 HQSLEYKRLLDAKTRLEMEIATYRRLLEGEDTRFS 186
>02016
          Length = 3061

 Score = 90.5 bits (223), Expect = 1e-18,   Method: Compositional matrix adjust.
 Identities = 68/219 (31%), Positives = 114/219 (52%), Gaps = 3/219 (1%)
 Frame = +3

Query: 200 ESTLQSFRQDVDNASLARLDLERKVESLQEEIAFLKKLHDXXXXXXXXXXXXXXXXXDVD 259
           E  L   ++ ++  +L R+DLE +++SL+EEI F  ++++                 D  
Sbjct: 141 EKQLAKLKKQLEEETLLRVDLENRLQSLKEEINFKSQVYEQELEESRVRTTVEIEQVDGR 320

Query: 260 VS---KPDLTAALRDVRQQYESVAAKNLQEAEEWYKSKFADLSEAANRNNDALRQAKQES 316
           +    +  L  ALR++R Q+ES       E E  Y++K ADL   ANR+N A   A +E 
Sbjct: 321 LEHEYEQRLLEALREIRAQHESDLQTVRVELETLYENKIADLKAQANRSNSASGSAWEEL 500

Query: 317 NEYRRQVQSLTCEVDALKGTNESLERQMREMEENFALEAANYQDTIGRLQDEIQNMKEEM 376
              R++   L  E+  LK      E ++ ++E   A E   ++  + +  DE+  ++  +
Sbjct: 501 RITRKRADDLGAELAKLKAETAGFELRISDLESQLAREREEFRLRLAQKDDELAELRLTL 680

Query: 377 ARHLREYQDLLNVKMALDIEIATYRKLLEGEESRISLPL 415
              ++EY DLL++K+ LD EI  YRKLLE EESR+++ L
Sbjct: 681 EEQMQEYSDLLDIKIRLDREIDAYRKLLESEESRLNISL 797
>26996
          Length = 386

 Score = 59.7 bits (143), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 33/80 (41%), Positives = 52/80 (65%), Gaps = 3/80 (3%)
 Frame = -1

Query: 97  KNTRTNEKVELQELNDRFANYIDKVRFLEQQNKILLAEL---EQLKGQGKSRLGDLYEEE 153
           ++TR  E+  LQ LNDR ANYID+VRFLE +N  L  ++   E++  +  S + +LYE E
Sbjct: 242 RSTRQQEQESLQGLNDRLANYIDRVRFLEAENSRLSTQVQSTEEIVKREVSSVKNLYETE 63

Query: 154 MRELRRQVDQLTNDKARVEV 173
           + + RR +D    +KAR+++
Sbjct: 62  LADARRLLDDTAREKARIQI 3
>22014
          Length = 353

 Score = 52.4 bits (124), Expect = 4e-07,   Method: Compositional matrix adjust.
 Identities = 25/53 (47%), Positives = 38/53 (71%)
 Frame = -1

Query: 362 IGRLQDEIQNMKEEMARHLREYQDLLNVKMALDIEIATYRKLLEGEESRISLP 414
           + +L++E+  ++ EM   L E Q L++ K++L++EIA YRKLLE EESR  LP
Sbjct: 212 VNQLKEEMNKLRAEMEAMLVELQTLMDAKLSLELEIAAYRKLLETEESRTGLP 54
>19956
          Length = 536

 Score = 37.0 bits (84), Expect = 0.016,   Method: Compositional matrix adjust.
 Identities = 43/163 (26%), Positives = 76/163 (46%), Gaps = 45/163 (27%)
 Frame = -3

Query: 122 RFLEQQNKILLAELEQLKGQGK---SRLGDLYEEEMRELRRQVDQLTNDKARVEVE---- 174
           R+LE +N  L  +++  +   K   S + +LYE E+ + R+ +D+   +KARV++E    
Sbjct: 534 RYLEAENNRLSTQIQSTEETVKREVSSVKNLYENELSDARKVLDETAKEKARVQIEASTF 355

Query: 175 ----RDNLAEDIMRLRE------------------------------KLQEEM----LQR 196
                D LA+   R RE                              +LQ++M     Q 
Sbjct: 354 KTKYEDMLAKYKQRDREASGAEQRVENLEVQLADLSAKLNDADAARARLQKDMSGLRSQL 175

Query: 197 EEAESTLQSFRQDVDNASLARLDLERKVESLQEEIAFLKKLHD 239
              E  L + +Q ++  +L R+DLE +V+SL+EE+ F  +L++
Sbjct: 174 SSQEQQLGTAKQQIEEETLLRVDLENRVQSLKEELQFKAQLYE 46
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|46518528|ref|NP_997508.1| acyl-CoA synthetase
long-chain family member 4 isoform 1 [Mus musculus]
         (711 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

02291                                                                 117   2e-26
34113                                                                 104   1e-22
03756                                                                  91   1e-18
14024                                                                  65   9e-11
21564                                                                  65   1e-10
20450                                                                  60   2e-09
26510                                                                  59   6e-09
13327                                                                  44   3e-04
00262                                                                  39   0.010
37217                                                                  36   0.058
19187                                                                  35   0.12 
17879                                                                  30   4.3  
24936                                                                  29   5.9  
>02291
          Length = 3161

 Score =  117 bits (292), Expect = 2e-26,   Method: Compositional matrix adjust.
 Identities = 99/343 (28%), Positives = 163/343 (47%), Gaps = 17/343 (4%)
 Frame = -1

Query: 268  TPSDMAIVMYTSGSTGRPKGVMMHHSNLI----AGMTGQCERIPGLGPKDTYIGYLPLAH 323
            +P+   +++YTSG+TG PKGVM+ H N+       M+   +++     + + I YLPL+H
Sbjct: 2870 SPNKCCVLIYTSGTTGTPKGVMLSHDNITYTVAVNMSSTMQQLNTKFGQQSGISYLPLSH 2691

Query: 324  VLELTAEISC-FTYGCRIGYSSPLTLSDQSSKIKKGSKG-DCTVLKPTLMAAVPEIMDRI 381
            +     +I     +G    ++ P  L        KGS G     ++P +   VP + +++
Sbjct: 2690 IAAQMMDIYVXIGFGGTTYFAQPDAL--------KGSLGATLREVRPHIFLGVPRVWEKM 2535

Query: 382  YKNVMSKVQEMNYVQKTLFKIGYDYKLEQIKKGY----------DAPLCNLILFKKVKAL 431
             + + +  + +  ++K   KIG   K   +K  Y            PL N ++FKKV+ L
Sbjct: 2534 QETMQTAARSVTGMKK---KIGAWAKGVGLKANYAIMEGRSPPAXXPLANALVFKKVRGL 2364

Query: 432  LG-GNVRMMLSGGAPLSPQTHRFMNVCFCCPIGQGYGLTESCGAGTVTEVTDYTTGRVGA 490
            LG     M LSG AP++ +T  +  +    PI + YG++E  G  TV          VG 
Sbjct: 2363 LGLDRCLMQLSGAAPIAKETLEYF-MSLNVPICEVYGMSECSGPHTVGFPKVNRVNSVGR 2187

Query: 491  PLICCEIKLKDWQEGGYTVHDKPNPRGEIVIGGQNISMGYFKNEEKTAEDYCVDENGQRW 550
             L  C  +L +  E G          GE+V+ G+++ MGY  +EEKT E   +D+ G   
Sbjct: 2186 ELNGCTTELANQDEDG---------NGEVVMHGRHVFMGYLNDEEKTKE--ALDDAGG-- 2046

Query: 551  FCTGDIGEFHPDGCLQIIDRKKDLVKLQAGEYVSLGKVEAALK 593
              +GD+G+   DG L I  R K+L+    GE +    +E  +K
Sbjct: 2045 LHSGDVGKKDKDGFLFITGRIKELIITAGGENIPPVAIEDRVK 1917
>34113
          Length = 694

 Score =  104 bits (260), Expect = 1e-22,   Method: Compositional matrix adjust.
 Identities = 67/189 (35%), Positives = 102/189 (53%), Gaps = 4/189 (2%)
 Frame = -3

Query: 137 NFGSGLTALGLKP--KNTIAIFCETRAEWMIAAQTCFKYNFPLVTLYATLGREAVVHGLN 194
           +FGSGL ALG+KP       IF +  +EW+IA Q C  Y+   V LY TLG EAV + +N
Sbjct: 563 HFGSGLFALGVKPGQDTNFGIFTQNSSEWVIADQACQMYSMVTVALYDTLGVEAVKYVVN 384

Query: 195 ESEASYLITSVELLESKLKAALVDINCVKHIIYVDNKT--INRAEYPEGLEIHSMQSVEE 252
            +E   ++   E+    L     ++ C+K I+  +  T  + +     G++I     VE+
Sbjct: 383 LAEIGTVVCDKEVRAKILLEGKSELPCLKLIVMXEEITEELQQKAQRAGVKIIRFSEVED 204

Query: 253 LGAKPENLSVPPSRPTPSDMAIVMYTSGSTGRPKGVMMHHSNLIAGMTGQCERIPGLGPK 312
           LG K  N+   P  P PSD+  + +TSG+TG PKGV++ H+NL+A ++        +  K
Sbjct: 203 LGKK--NIR-EPLLPKPSDVCTICFTSGTTGNPKGVVLTHANLVANVSS-----VKVSLK 48

Query: 313 DTYIGYLPL 321
           DT +   PL
Sbjct: 47  DTMVWIQPL 21
>03756
          Length = 992

 Score = 91.3 bits (225), Expect = 1e-18,   Method: Compositional matrix adjust.
 Identities = 53/179 (29%), Positives = 92/179 (51%), Gaps = 5/179 (2%)
 Frame = +2

Query: 123 YKWINYLEVNCRVNNFGSGLTALGLKPKNT--IAIFCETRAEWMIAAQTCFKYNFPLVTL 180
           + W++Y +V  R + FGSGL + G++P N+  + I+     EW +A   C  Y+   V L
Sbjct: 275 FSWMSYRQVLDRAHCFGSGLISKGVQPSNSSFVGIYSGNCVEWSLADLGCHMYSMVPVPL 454

Query: 181 YATLGREAVVHGLNESEASYLITSVELLESKLKAALVDINCVKHIIYVDN---KTINRAE 237
           Y TLG +A V+ +N+++   ++        +L      +  +K  I+      + I    
Sbjct: 455 YDTLGPQACVYIINQTKLCTVVCDDVNKAKRLLEIADQVPSLKRFIFTGKTWPQDIRDLA 634

Query: 238 YPEGLEIHSMQSVEELGAKPENLSVPPSRPTPSDMAIVMYTSGSTGRPKGVMMHHSNLI 296
               +E+ + + +E +G K     +PP    P D+A + YTSG+TG PKGVM+ H+N +
Sbjct: 635 NERKVELLTFKEIESIGTKDTRDPIPPK---PDDLATLCYTSGTTGDPKGVMLTHANFL 802
>14024
          Length = 655

 Score = 65.1 bits (157), Expect = 9e-11,   Method: Compositional matrix adjust.
 Identities = 52/193 (26%), Positives = 90/193 (46%), Gaps = 2/193 (1%)
 Frame = +3

Query: 427 KVKALLG-GNVRMMLSGGAPLSPQTHRFMNVCFCCPIGQGYGLTESCGAGTVTEVTDYTT 485
           KV+A LG   V  ++S  AP+SP+T ++  +     I   +G++E+ G  T+ +      
Sbjct: 6   KVRAALGFDRVISLVSAAAPMSPETKKYF-LSLDMKILDAFGMSETSGCHTLCQPDSTLL 182

Query: 486 GRVGAPLICCEIKLKDWQEGGYTVHDKPNPRGEIVIGGQNISMGYFKNEEKTAEDYCVDE 545
             +G  L  CE K+         ++   N  GE+ I G+++ MGY  N+EKT E      
Sbjct: 183 NSIGKSLPGCESKI---------INQDANGHGELCIRGRHVFMGYISNKEKTEESL---- 323

Query: 546 NGQRWFCTGDIGEFHPDGCLQIIDRKKDLVKLQAGEYVSLGKVEAALKNCPLIDNIC-AF 604
           +   W  +GD+      G + +  R K+L+    GE +    +E  +K    +D I  AF
Sbjct: 324 DDDCWLHSGDLAYIDDKGYVCLTGRLKELIITAGGENIPPVHIENIIKK--ELDGISNAF 497

Query: 605 AKSDQSYVISFVV 617
              +Q   ++ +V
Sbjct: 498 LVGEQRKYLTVLV 536
>21564
          Length = 509

 Score = 65.1 bits (157), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 39/136 (28%), Positives = 72/136 (52%), Gaps = 4/136 (2%)
 Frame = +1

Query: 123 YKWINYLEVNCRVNNFGSGLTALGLKPKNT--IAIFCETRAEWMIAAQTCFKYNFPLVTL 180
           Y+WI Y E+  R    G+GL ALGL P+NT  + ++ + R E++I     + Y+   V L
Sbjct: 79  YRWITYNELLQRAEYIGAGLIALGLSPQNTTRVGVYSQNRPEYVITDCGLWAYSMVGVPL 258

Query: 181 YATLGREAVVHGLNESEASYLITSVELLESKLKAALVDINCVKHIIYVDNKTINRAEYPE 240
           Y TLG EA  H LN++E   ++    +    +   L +   +K ++ +++ T    +  +
Sbjct: 259 YDTLGAEACNHILNQAEIKVVVCDTNVKVKNMLQRLSETPNLKILVVMEDITGESRQMAD 438

Query: 241 --GLEIHSMQSVEELG 254
             G+++   + +EE+G
Sbjct: 439 RAGVKLLQFKELEEMG 486
>20450
          Length = 775

 Score = 60.5 bits (145), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 47/145 (32%), Positives = 69/145 (47%), Gaps = 3/145 (2%)
 Frame = -3

Query: 476 TVTEVTDYTTGRVGAPLICCEIKLKDWQEGGYTVHDKPNPRGEIVIGGQNISMGYFKNEE 535
           T +    Y  G  G P    E K+ D + G        N  G++   G  I  GY KN +
Sbjct: 665 TFSTPAKYELGSCGFPTPNAEFKVIDSETGKCL---GVNQAGDLYKRGPLIMRGYHKNPQ 495

Query: 536 KTAEDYCVDENGQRWFCTGDIGEFHPDGCLQIIDRKKDLVKLQAGEYVSLGKVEAALKNC 595
            TA+   +D  G  W  TGD+G+F  +G L I+DRKK+L+K + GE V+   +E  L + 
Sbjct: 494 ATAD--TIDAQG--WLKTGDVGQFDSNGFLYIVDRKKELIKYK-GEQVAPAMLEDVLLSH 330

Query: 596 PLIDNICAFAKSDQ---SYVISFVV 617
           P I +     + D       ++FVV
Sbjct: 329 PGISDAAVIGRPDDMAGELPMAFVV 255
>26510
          Length = 1692

 Score = 59.3 bits (142), Expect = 6e-09,   Method: Compositional matrix adjust.
 Identities = 53/196 (27%), Positives = 94/196 (47%)
 Frame = +1

Query: 191 HGLNESEASYLITSVELLESKLKAALVDINCVKHIIYVDNKTINRAEYPEGLEIHSMQSV 250
           H L  + A  + T  +L+   ++AA+ D +    +  V   T   AE  EG E       
Sbjct: 487 HMLTHNGACAMFTIPQLV-PLVQAAIADPDLPHSVKEV--YTFGHAE--EGTEFFQALMS 651

Query: 251 EELGAKPENLSVPPSRPTPSDMAIVMYTSGSTGRPKGVMMHHSNLIAGMTGQCERIPGLG 310
           ++  + P+N+ + PS    +D+  + Y+SG+TG PKGVM+ H N++A +  Q   +    
Sbjct: 652 DDGKSFPDNIDINPS----TDVLFLPYSSGTTGLPKGVMLSHRNIVANIL-QFRELANTQ 816

Query: 311 PKDTYIGYLPLAHVLELTAEISCFTYGCRIGYSSPLTLSDQSSKIKKGSKGDCTVLKPTL 370
           P+D  +G LP  H+  LT    C  +G     +  +T+     ++   S  D  +   TL
Sbjct: 817 PEDRTLGLLPFFHIYGLT----CVQFGTLYDGAELVTVPRFEPELFLKSLHDRKI---TL 975

Query: 371 MAAVPEIMDRIYKNVM 386
           + AVP ++  + ++ M
Sbjct: 976 LQAVPPVVLFLARHPM 1023
>13327
          Length = 549

 Score = 43.5 bits (101), Expect = 3e-04,   Method: Composition-based stats.
 Identities = 23/59 (38%), Positives = 32/59 (54%)
 Frame = +3

Query: 550 WFCTGDIGEFHPDGCLQIIDRKKDLVKLQAGEYVSLGKVEAALKNCPLIDNICAFAKSD 608
           W  +GD+G F  DG L I+DRKK+L+K +A E V    +E  L   P I +     + D
Sbjct: 3   WLDSGDVGYFDSDGFLYIVDRKKELIKFKA-EQVPPAMLEDVLLTHPGISDAAVIGRPD 176
>00262
          Length = 1036

 Score = 38.5 bits (88), Expect = 0.010,   Method: Compositional matrix adjust.
 Identities = 36/152 (23%), Positives = 63/152 (41%), Gaps = 9/152 (5%)
 Frame = -1

Query: 477  VTEVTDYTTGRVGAPLICCEIK-----LKDWQEGGYTVHDKPNPRGEIVIGGQNISMGYF 531
            VT+   Y  G  G   +  +++     L+D  EG           GEI+     +   Y 
Sbjct: 1018 VTKPDTYQDGMTGPAAVGVQVRIVDEHLQDVGEGQ---------TGEIIAKSPALYSRYI 866

Query: 532  KNEEKTAEDYCVDENGQRWFCTGDIGEFHPDGCLQIIDRKKDLVKLQAGEYVSL-GKVEA 590
             N+E   + +  D     WF T D+G F+ D  +  + R+ D +    G Y+   G +E 
Sbjct: 865  DNDEAAKKSFTPDG----WFRTDDMGCFNQDKHIIHLGRRTDAIT--RGAYLCYPGWLET 704

Query: 591  ALKNCPLIDNICAFAKSD---QSYVISFVVPN 619
             L+  P + ++C    +D      + + V+PN
Sbjct: 703  LLRRSPSVRDVCVVPVADPVLHHEICACVIPN 608
>37217
          Length = 548

 Score = 35.8 bits (81), Expect = 0.058,   Method: Compositional matrix adjust.
 Identities = 32/104 (30%), Positives = 45/104 (43%), Gaps = 1/104 (0%)
 Frame = -2

Query: 435 NVRMMLSGGAPLSPQTHRFMNVCFCCP-IGQGYGLTESCGAGTVTEVTDYTTGRVGAPLI 493
           ++ ++L G APLS +T   +      P I QGYGL+ES  +  V        G V    +
Sbjct: 340 SLLVLLCGAAPLSRETEDQIKERLGIPFIRQGYGLSESTLSVLVQNDEHCKPGSVXVLNV 161

Query: 494 CCEIKLKDWQEGGYTVHDKPNPRGEIVIGGQNISMGYFKNEEKT 537
               K+ D   G    H   N RGE+   G  I  GY  ++  T
Sbjct: 160 GVYAKVIDPDTGK---HLGANERGELCFKGPGIMKGYIGDKRST 38
>19187
          Length = 742

 Score = 34.7 bits (78), Expect = 0.12,   Method: Compositional matrix adjust.
 Identities = 24/93 (25%), Positives = 43/93 (46%), Gaps = 1/93 (1%)
 Frame = +2

Query: 517 GEIVIGGQNISMGYFKNEEKTAEDYCVDENGQRWFCTGDIGEFHPDGCLQIIDRKKDLVK 576
           GEI+     +   Y  N+E   + +  D     WF T D+G F+ D  +  + R+ D + 
Sbjct: 449 GEIIAKSPALYSRYIDNDEAAKKSFTPDG----WFRTDDMGCFNQDKHIIHLGRRTDAIT 616

Query: 577 LQAGEYVSL-GKVEAALKNCPLIDNICAFAKSD 608
              G Y+   G +E  L++ P + ++C    +D
Sbjct: 617 R--GAYLCYPGWLETLLRHSPSVRDVCVVPVAD 709
>17879
          Length = 480

 Score = 29.6 bits (65), Expect = 4.3,   Method: Composition-based stats.
 Identities = 17/37 (45%), Positives = 23/37 (62%), Gaps = 1/37 (2%)
 Frame = -1

Query: 639 ICNNPAMEA-EILKEIREAANAMKLERFEIPIKVRLS 674
           + N P M   E LKEIRE A  ++ +RFE+  + RLS
Sbjct: 114 VYNVPDMSMDETLKEIREMAKQIRGKRFELRDEKRLS 4
>24936
          Length = 481

 Score = 29.3 bits (64), Expect = 5.9,   Method: Composition-based stats.
 Identities = 12/28 (42%), Positives = 18/28 (64%)
 Frame = +3

Query: 6   NVLTIILLPVHLLITIYSALIFIPWYFL 33
           N+   I+L  H+L T+Y +  +IP YFL
Sbjct: 276 NIGLFIILKYHILRTLYPSYSYIPLYFL 359
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|65301475|ref|NP_619611.2| 3-mercaptopyruvate
sulfurtransferase [Mus musculus]
         (297 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

18406                                                                  92   2e-26
38240                                                                 102   2e-22
09126                                                                  91   4e-19
08482                                                                  29   2.9  
04503                                                                  28   6.0  
>18406
          Length = 825

 Score = 92.0 bits (227), Expect(2) = 2e-26,   Method: Compositional matrix adjust.
 Identities = 56/189 (29%), Positives = 93/189 (49%), Gaps = 1/189 (0%)
 Frame = +2

Query: 10  LVSAQWVAEALKAPRSSQPLKLLDASWYLPKLGRDARREFEERHIPGAAFFDIDRCSDHT 69
           LV+ +W+ + + +      L +LD SW   K   + + EF++RHI GA + ++     H+
Sbjct: 77  LVTCEWLHDKIGSGNHGN-LVILDVSWSSHK---NCQEEFQQRHIQGARYLNV-MVGPHS 241

Query: 70  SPYDHMLPNATHFADYAGSLGVSAATHVVIYDGSDQ-GLYSAPRVWWMFRAFGHHSVSLL 128
             +   LP    F   A ++GVS  +HV++Y  SD  G + + R WW F  +G   VS+L
Sbjct: 242 QLFPRNLPPQEVFEQEARAVGVSNDSHVIVYSDSDNCGFFMSSRAWWTFTVYGAKRVSVL 421

Query: 129 DGGFRHWLNQNLPISSGKSHSEPAEFSAQLDPSFIKTHEDILENLDARRFQVVDARAAGR 188
           +GG + W++     +S  S  +   F+         T+EDI + L +    V+D   A  
Sbjct: 422 NGGLQRWVSLGYDTTSDSSPCKVGNFTVXFTDQHRLTYEDISQRLHSNDVTVLDLTCADE 601

Query: 189 FQGTQPEPR 197
            Q  +P PR
Sbjct: 602 IQ-*RPHPR 625

 Score = 44.3 bits (103), Expect(2) = 2e-26,   Method: Compositional matrix adjust.
 Identities = 25/75 (33%), Positives = 41/75 (54%), Gaps = 1/75 (1%)
 Frame = +3

Query: 203 GHIPGSVNIPFTEFLTNEGLE-KSPEEIKRLFKEKKVDLSKPLVATCGSGVTACHVVLGA 261
           GHI G+ + P+T+ +     + KS E+IK++      DL+KP+V  C SG+++C + L  
Sbjct: 612 GHIQGAKSCPYTQLVDPSTQQMKSAEDIKKV----GADLTKPMVTYCNSGMSSCTLALAC 779

Query: 262 FLCGKSDVPVYDGSW 276
            L       VY G +
Sbjct: 780 RLAIGPRFAVYHGGF 824
>38240
          Length = 669

 Score =  102 bits (253), Expect = 2e-22,   Method: Compositional matrix adjust.
 Identities = 47/83 (56%), Positives = 63/83 (75%), Gaps = 2/83 (2%)
 Frame = +2

Query: 208 SVNIPFTEFLTNEGLE--KSPEEIKRLFKEKKVDLSKPLVATCGSGVTACHVVLGAFLCG 265
           SVN+PFT  L +E  +  K+ EE+++LF +  VDL+KP+ ATCGSGV+AC V L A++ G
Sbjct: 2   SVNLPFT-LLMDESKQTLKTKEELQQLFDDLPVDLTKPVAATCGSGVSACMVALAAYVVG 178

Query: 266 KSDVPVYDGSWVEWYMRAQPEHI 288
           K D+ VYDGSWVEWY RAQP+ +
Sbjct: 179 KEDMAVYDGSWVEWYQRAQPDQL 247
>09126
          Length = 595

 Score = 91.3 bits (225), Expect = 4e-19,   Method: Compositional matrix adjust.
 Identities = 51/174 (29%), Positives = 86/174 (49%), Gaps = 1/174 (0%)
 Frame = +2

Query: 116 MFRAFGHHSVSLLDGGFRHWLNQNLPISSGKSHSEPAEFSAQLDPSFIKTHEDILENLDA 175
           +F  +G   VS+L+GG + W++     +S  S  +   F+ Q       T+EDI + L +
Sbjct: 11  LFTVYGAKRVSVLNGGLQRWVSLGYDTTSDSSPCKVGNFTVQFTDQHRLTYEDISQRLHS 190

Query: 176 RRFQVVDARAAGRFQGTQPEPRDGIEPGHIPGSVNIPFTEFLTNEGLE-KSPEEIKRLFK 234
               V+D+RA  ++             GHI G+ + P+T+ +     + KS E++K++F+
Sbjct: 191 NDVTVLDSRAPTKY-----------NDGHIQGAKSCPYTQLVDPSTQQMKSAEDLKKVFQ 337

Query: 235 EKKVDLSKPLVATCGSGVTACHVVLGAFLCGKSDVPVYDGSWVEWYMRAQPEHI 288
               DL+KP+V  C SG+++C + L   L       VY G + EW   A  E I
Sbjct: 338 SVGADLTKPMVTYCNSGMSSCTLALACRLAIGPRFAVYHGGFTEWKNSAPEEDI 499
>08482
          Length = 1339

 Score = 28.9 bits (63), Expect = 2.9,   Method: Compositional matrix adjust.
 Identities = 12/37 (32%), Positives = 21/37 (56%)
 Frame = -3

Query: 8   RALVSAQWVAEALKAPRSSQPLKLLDASWYLPKLGRD 44
           R +  +  +A+  K+P S+   + +  SWYL K+G D
Sbjct: 458 RVICKSDPLAKCDKSPTSASHCRQIICSWYLKKIGHD 348
>04503
          Length = 1609

 Score = 27.7 bits (60), Expect = 6.0,   Method: Compositional matrix adjust.
 Identities = 11/29 (37%), Positives = 18/29 (62%)
 Frame = +2

Query: 16  VAEALKAPRSSQPLKLLDASWYLPKLGRD 44
           +A+  K+P S+   + +  SWYL K+G D
Sbjct: 815 LAKCDKSPTSASHCRQIICSWYLKKIGHD 901
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|82899087|ref|XP_485660.2| PREDICTED: similar to GPI7
protein isoform 1 [Mus musculus]
         (975 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

31642                                                                 117   2e-26
08638                                                                  58   2e-08
18059                                                                  58   2e-08
07982                                                                  42   8e-04
19771                                                                  35   0.16 
31271                                                                  34   0.22 
03696                                                                  31   3.1  
28740                                                                  30   3.7  
>31642
          Length = 1040

 Score =  117 bits (293), Expect = 2e-26,   Method: Compositional matrix adjust.
 Identities = 85/280 (30%), Positives = 135/280 (48%), Gaps = 18/280 (6%)
 Frame = -3

Query: 183  FFVSDYIEVDKNVTRHLDKVLKRGDWDVLILHYLGLDHIGHISGPNSPLIGHKLSEMDSV 242
             FV+D+ EVD NVTRHL   LK  DWDV+ILHYLGLDH+GH+  P+  +   KL EMD+V
Sbjct: 1026 LFVTDFTEVDVNVTRHLSGELKAEDWDVMILHYLGLDHLGHLYAPDPDIFSPKLREMDAV 847

Query: 243  LMKIHTSLLSKDRETLLPSLLVLCGDHGMSETGSHGASSTEEVSTPLLLISSAFERKPGD 302
            + +I+T++ S        + LV+CGDHG+S+ G HG +S EE + P++++S         
Sbjct: 846  VQQIYTAMASWGGGGR--AALVVCGDHGISDQGGHGGASPEETNVPIIILSP-------- 697

Query: 303  IRHPKHVQQTDLAATLAIGLGLPIPKDSVGSLLFPVIEGK----------PMREQLRFLH 352
              H       +  +  +  + +P+   S G      I GK          P R +    +
Sbjct: 696  --HTTFXAXPEETSRYSR*ICVPLSPPS*GCPYLVTIWGKWWWKRCP*TRPWRTKCAIFN 523

Query: 353  LNTLQLSKLLQENVPSYEK------DPGFEQFKMAEKLHGNWVKLHLEENHSDILLGLGT 406
                + S           K      D  +  ++ A   H +W+ L    +H+     +G 
Sbjct: 522  *MQSRWSMFWNRT*EILRKRNTLITDQAYRLYQDALAAHTSWLSLRNSSSHA-AWETIGK 346

Query: 407  KVLRHYLGALKTLSLSLSTQVAQYDMYSM--AVLALFLLS 444
            +VL  Y  A+  +S  +      YDMY +  A++ L+++S
Sbjct: 345  RVLLGYQDAIHRMSQRVGQTSTSYDMYGIVVAIVCLWIVS 226
>08638
          Length = 992

 Score = 58.2 bits (139), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 24/37 (64%), Positives = 33/37 (89%)
 Frame = +1

Query: 920 SVPVATYIVLVTSLRYHLFIWSVFSPKLLYEGMHLLI 956
           ++P+A + VLVT++RYHLF+W+VFSPKLLYEG  LL+
Sbjct: 688 ALPLAVFTVLVTAMRYHLFVWTVFSPKLLYEGYLLLV 798
>18059
          Length = 1618

 Score = 58.2 bits (139), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 29/54 (53%), Positives = 38/54 (70%), Gaps = 7/54 (12%)
 Frame = -3

Query: 910  RSCFCYALICS-------VPVATYIVLVTSLRYHLFIWSVFSPKLLYEGMHLLI 956
            R C  Y  +CS       +P+A + VLVT++RYHLF+W+VFSPKLLYEG  LL+
Sbjct: 1466 RLCEAYRELCSTALLTRALPLAVFTVLVTAMRYHLFVWTVFSPKLLYEGYLLLV 1305
>07982
          Length = 901

 Score = 42.4 bits (98), Expect = 8e-04,   Method: Compositional matrix adjust.
 Identities = 23/71 (32%), Positives = 36/71 (50%), Gaps = 1/71 (1%)
 Frame = -3

Query: 209 DVLILHYLGLDHIGHISGPNSPLIGHKLSEMDSVLMKIHTSLLSKDRETLLPSL-LVLCG 267
           D + L++   D  GH  GP SP +  K+ +MD VL  I   L   D   L  ++ +++  
Sbjct: 587 DFVALYFNEPDTTGHTYGPGSPEVAQKVRDMDEVLGSIVREL---DNNNLSDTVNVIVTS 417

Query: 268 DHGMSETGSHG 278
           DHGM++   H 
Sbjct: 416 DHGMTDVDMHN 384
>19771
          Length = 777

 Score = 35.0 bits (79), Expect = 0.16,   Method: Compositional matrix adjust.
 Identities = 14/15 (93%), Positives = 14/15 (93%)
 Frame = +3

Query: 559 ASSFVEEEHQTWYFL 573
           ASSFVEEEHQTWYF 
Sbjct: 186 ASSFVEEEHQTWYFF 230
>31271
          Length = 330

 Score = 34.3 bits (77), Expect = 0.22,   Method: Compositional matrix adjust.
 Identities = 14/15 (93%), Positives = 14/15 (93%)
 Frame = -3

Query: 559 ASSFVEEEHQTWYFL 573
           ASSFVEEEHQTWYF 
Sbjct: 97  ASSFVEEEHQTWYFF 53
>03696
          Length = 1593

 Score = 30.8 bits (68), Expect = 3.1,   Method: Compositional matrix adjust.
 Identities = 13/23 (56%), Positives = 14/23 (60%)
 Frame = -3

Query: 575  NTLCLALSQETCRSYFLGDECEP 597
            N L L+LS  TC S  LGD C P
Sbjct: 1102 NVLALSLSMATCTSVLLGDPCPP 1034
>28740
          Length = 823

 Score = 30.4 bits (67), Expect = 3.7,   Method: Composition-based stats.
 Identities = 11/30 (36%), Positives = 19/30 (63%)
 Frame = -3

Query: 915 YALICSVPVATYIVLVTSLRYHLFIWSVFS 944
           + L C+ P++  I LV  +R+ + IW+ FS
Sbjct: 215 HKLFCTTPISFRITLVARIRWMILIWNHFS 126
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|12963867|ref|NP_076401.1| SCY1-like 1 [Mus musculus]
         (806 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

06358                                                                 116   3e-26
01707                                                                  50   3e-06
09606                                                                  44   2e-04
13592                                                                  43   4e-04
00300                                                                  43   5e-04
07833                                                                  41   0.002
14126                                                                  37   0.029
17975                                                                  35   0.11 
00392                                                                  34   0.23 
04852                                                                  33   0.64 
00394                                                                  32   0.92 
31789                                                                  32   1.1  
11185                                                                  32   1.4  
12786                                                                  29   5.8  
29781                                                                  29   5.8  
11214                                                                  29   7.8  
>06358
          Length = 1517

 Score =  116 bits (291), Expect = 3e-26,   Method: Compositional matrix adjust.
 Identities = 114/475 (24%), Positives = 194/475 (40%), Gaps = 44/475 (9%)
 Frame = +3

Query: 29  WILHRGRKKATGSAVSIFVYDVKP-------GAEEQTQVAKAAFKRLKTLRHPNILAYID 81
           W +    KK+T    S+FV++ K          E   +V +   ++L  LRHP ILA I+
Sbjct: 48  WKVFAASKKSTKEEASVFVFEKKSVDRYSRRDREAIVEVLRVGVQQLTKLRHPKILAVIN 227

Query: 82  GLE-TEKCLHIVTEAV-----TPLGTY-----LKARAEAGGLKEQELSWGLHQIVKALSF 130
            LE + + L   TE V       LG       +    +   L + E+  GL Q+ +AL F
Sbjct: 228 PLEESRETLAFATEPVFASLANVLGDLSSIXTVPKELQDYQLYDVEIKHGLLQVTEALGF 407

Query: 131 LVNDCNLIHNNVCMAAVFVDRAGEWKLGGLDYMYSAQGNGGGPPS-------KGIPELEQ 183
           L ND  ++H NVC  A+ + + G WKL G ++   +       PS         I  + Q
Sbjct: 408 LHNDAKMMHRNVCPEAIMLTKLGSWKLAGYEFCVRSSDPQSTDPSYPFYEWRSDIAPVTQ 587

Query: 184 YDPPELADSSSRAVREKWSADMWRLGCLIWEVF---------NGSL----PRAAALRNP- 229
                +A      ++    +DM+ LG L++ VF         NG L      A  LR+  
Sbjct: 588 PHLDFMAPEYVLTMQCGTGSDMFSLGLLVYSVFAKGKPLFECNGELSAFKSNAEELRHMR 767

Query: 230 ----GKIPKSLVTHYCELVGANPKVRPNPARFLQNCRAPGGFMSNRFVETNLFLEEIQIK 285
               G +P+ L  H   L+   P VRP+ A   Q  + P  F  +    T  +++ +  +
Sbjct: 768 VSLLGVVPEDLRDHVKLLLNIEPAVRPDAA---QLSKVP--FFEDVGCITLQYMDTLFQR 932

Query: 286 EPAEKQKFFQELSKSLDSFPEDFCRHKVLPQLLTAFEFGNAGAVVLTPLFKVGKSLRAEE 345
           +  EK  FF+ L K +   P+     ++LP L       +    +L  +  V +     E
Sbjct: 933 QNIEKSNFFKGLPKIIAKLPKRVSLQRILPALFKEGLNPDMVPFLLPSILLVAEQSTDTE 1112

Query: 346 YQEKIIPVVVKMFSSTDRAMRIRL-LQQMEQFIQYLDEPTVNTQIFPHVTHGFLDTNPAI 404
           Y+ +I P +V +F   +    + L LQ M   +       +   + P +       +P I
Sbjct: 1113YRTQIFPHLVPLFKLKEPVQVVLLFLQNMNLLLSKTLSADIQNHVLPMLFRAVEANSPQI 1292

Query: 405 REQTVKSMLLLAPKLNEANLNVELMKHFARLQAKDDQGPIRCNTTVCLGKIGSYL 459
           +E  +  +   A  +    L   L+    +L        +R N  +C+G++  ++
Sbjct: 1293QELCLSIIPTFAELIEYPTLKNSLVPRIKKLCLATTVLTVRVNCLLCMGQLLEHM 1457
>01707
          Length = 757

 Score = 50.4 bits (119), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 47/195 (24%), Positives = 83/195 (42%), Gaps = 5/195 (2%)
 Frame = +1

Query: 30  ILHRGRKKATGSAVSIFVYDVKPGAEEQTQVAKAAFKRLKTLRHPNILAYIDGLETEKCL 89
           ++ + R K T   V+I  +          ++A    + LK L+HPN++  I+    +K L
Sbjct: 109 VVFKCRNKETSQLVAIKKFVESEDDPLIKKIAMREIRMLKQLKHPNLVRLIEVFRRKKRL 288

Query: 90  HIVTEAV-----TPLGTYLKARAEAGGLKEQELSWGLHQIVKALSFLVNDCNLIHNNVCM 144
           H+V + V       L  Y +      GL E  +   ++Q + A++F  +  N IH +V  
Sbjct: 289 HLVFDYVDHTLLNELDRYPR------GLPEPMVKRIIYQTLLAVNF-CHQYNTIHRDVKP 447

Query: 145 AAVFVDRAGEWKLGGLDYMYSAQGNGGGPPSKGIPELEQYDPPELADSSSRAVREKWSAD 204
             + + R G+ KL   D+ ++    G G           Y  PEL    ++        D
Sbjct: 448 ENILITRQGQVKL--CDFGFARILTGPGDEYTDYVATRWYRAPELLVGDTQY---GPPVD 612

Query: 205 MWRLGCLIWEVFNGS 219
           +W +GC+  E+  G 
Sbjct: 613 VWAIGCVFAELLTGQ 657
>09606
          Length = 1300

 Score = 44.3 bits (103), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 49/216 (22%), Positives = 95/216 (43%), Gaps = 24/216 (11%)
 Frame = -3

Query: 30   ILHRGRKKATGSAVSIFVYDVKPGAEEQTQVAKAAFKRLKTLRHPNILAYIDGLETEKCL 89
            I+++GR+K T + V+I   + K    E T   +        + HPN++ + +  ET   L
Sbjct: 1070 IIYKGRRKGTINFVAIHCIE-KCKRPEVTNTVRMT----HDISHPNVVQFHEWYETSNHL 906

Query: 90   HIVTEAVTPLGTYLKARAEAGGLKEQEL-SWGLHQIVKALSFLVNDCNLIHNNVCMAAVF 148
             +V E  T  G+     A+   L E  +  +G+H +V  L + ++   ++ +++  + V 
Sbjct: 905  WLVVELCTG-GSLADILAQDHHLPETSIRDFGIH-LVTGLHY-IHSLGILFHDLRPSKVL 735

Query: 149  VDRAGEWKLG----------GLDYMY-------------SAQGNGGGPPSKGIPELEQYD 185
            +D +G  K             L+ ++             SA+      P+ G P    Y 
Sbjct: 734  LDTSGVLKFADFGLSKVEGENLEELFFKFAEAGDQWNIQSAEEMMKQVPTSGSP---TYM 564

Query: 186  PPELADSSSRAVREKWSADMWRLGCLIWEVFNGSLP 221
             PE+   +  ++     +D+W LGC+ +E+F+G  P
Sbjct: 563  APEVFQGAEPSIM----SDLWALGCVFYEMFSGHPP 468
>13592
          Length = 980

 Score = 43.1 bits (100), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 41/185 (22%), Positives = 81/185 (43%), Gaps = 2/185 (1%)
 Frame = +2

Query: 39  TGSAVSIFVYDVKPGAEEQTQVAKAAFKRLKTLRHPNILAYIDGLETEKCLHIVTEAVTP 98
           TG  +++    ++PG     +      K L+ ++H N++ Y  G+E  +   ++   +  
Sbjct: 56  TGELMAMKEIAIQPGETRALKNVAEELKILEGIKHKNLVRYY-GIEVHREELLIFMELCS 232

Query: 99  LGTYLKARAEAGGLKEQELSWGLHQIVKALSFLVNDCNLIHNNVCMAAVF-VDRAGEWKL 157
            GT        GGL E        Q++  ++ L +   ++H ++  A +F VD +   KL
Sbjct: 233 EGTLESLVELTGGLPEALSRRFTAQLLSGVAEL-HKHGIVHRDIKTANIFLVDGSNSLKL 409

Query: 158 GGLDYMYSAQGNGGGPPS-KGIPELEQYDPPELADSSSRAVREKWSADMWRLGCLIWEVF 216
           G        Q +   P   +G    + Y  PE+   ++     +  AD+W +GC++ E+ 
Sbjct: 410 GDFGSAVKIQAHTTVPGELQGYVGTQAYMAPEVFTKTNSDGHGRL-ADIWSVGCVVVEMA 586

Query: 217 NGSLP 221
           +G  P
Sbjct: 587 SGKRP 601
>00300
          Length = 2318

 Score = 42.7 bits (99), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 41/185 (22%), Positives = 81/185 (43%), Gaps = 1/185 (0%)
 Frame = -1

Query: 38   ATGSAVSIFVYDVKPGAEEQTQVAKAAFKRLKTLRHPNILAYIDGLETEKCLHIVTEAVT 97
            +TG  +++     +P   +Q +      K  + ++H N++ Y  G+E  K   ++     
Sbjct: 1589 STGELMALKEMKFQPNDLQQLREMCDEIKIFEGIQHENLVKYY-GVEVHKDEMLMFMEYC 1413

Query: 98   PLGTYLKARAEAGGLKEQELSWGLHQIVKALSFLVNDCNLIHNNVCMAAVFVDRAGEWKL 157
              GT     A   GL E  +     +IV A++ L ++ +++H ++  A +F+   G  KL
Sbjct: 1412 DTGTI--EEAAKMGLPEYLIRRYTREIVLAVNHL-HENSIVHRDIKGANIFLTSNGHVKL 1242

Query: 158  GGLDYMYSAQGNGGGPPS-KGIPELEQYDPPELADSSSRAVREKWSADMWRLGCLIWEVF 216
            G        + +   P     +     Y  PE+   + +    + +AD+W LGC++ E+ 
Sbjct: 1241 GDFGCSVKLKSHTTMPGEFHNLVGTTAYMAPEVFTQNDQGGYGR-AADIWSLGCVVIEMA 1065

Query: 217  NGSLP 221
             G  P
Sbjct: 1064 TGKRP 1050
>07833
          Length = 1504

 Score = 41.2 bits (95), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 43/163 (26%), Positives = 70/163 (42%), Gaps = 4/163 (2%)
 Frame = -3

Query: 65   FKRLKTLRHPNILAYIDGLETEKCLHIVTEAVTPLGT-YLKARAEAGGLKEQELSWGL-H 122
            F RL+   HPN+L  +        L ++++ + P G+ Y     E+G + +Q  S     
Sbjct: 1466 FPRLRIFNHPNVLPVLACCNQPPNLVLISQFM-PFGSLYNTLHGESGIVVDQNQSLRFAM 1290

Query: 123  QIVKALSFLVNDCNLIHNNVCMAA-VFVDRAGEWKLGGLDYMYSAQGNGG-GPPSKGIPE 180
             I + + FL +    I N +  +  V +D     ++   DY +S    G    P+   PE
Sbjct: 1289 DIARGMEFLHSMEPTIPNFLLTSKHVMIDEDLTARINMADYCFSFHEKGKVYSPAWMAPE 1110

Query: 181  LEQYDPPELADSSSRAVREKWSADMWRLGCLIWEVFNGSLPRA 223
              Q  P    D ++RA      ADMW    L+WE+    +P A
Sbjct: 1109 ALQRRP---DDINTRA------ADMWSFAILMWELETREVPFA 1008
>14126
          Length = 1265

 Score = 37.0 bits (84), Expect = 0.029,   Method: Compositional matrix adjust.
 Identities = 38/163 (23%), Positives = 71/163 (43%), Gaps = 8/163 (4%)
 Frame = +3

Query: 63  AAFKRLKTLRHPNILAYIDG-----LETEKCLHIVTEAVT-PLGTYLKARAEAGGLKEQE 116
           +  K+L+   HPN++  +D       + E  L++V E +   L TYL A+  + GL    
Sbjct: 345 SMLKQLEQYEHPNVVRLLDVSHNTITDREIRLNLVFEYIEHDLATYL-AKCPSPGLGPDR 521

Query: 117 LSWGLHQIVKALSFLVNDCNLIHNNVCMAAVFVDRAGEWKLG--GLDYMYSAQGNGGGPP 174
           +   + Q++  + FL ++  ++H ++    + + + G  KL   GL  +YS         
Sbjct: 522 IKDLMLQLLNGVDFLHSN-RIVHRDLKPQNLLISKDGRLKLADFGLARIYSFHM-----A 683

Query: 175 SKGIPELEQYDPPELADSSSRAVREKWSADMWRLGCLIWEVFN 217
              +     Y  PE+   +        S D+W  GC+  E+F 
Sbjct: 684 LTTVVVTLWYRSPEVLMQAEYGT----SVDIWSCGCIFAELFT 800
>17975
          Length = 449

 Score = 35.0 bits (79), Expect = 0.11,   Method: Composition-based stats.
 Identities = 30/129 (23%), Positives = 61/129 (47%), Gaps = 1/129 (0%)
 Frame = +3

Query: 30  ILHRGRKKATGSAVSIFVYDVKPGAEEQTQVAKAAFKRLKTLRHPNILAYIDGLETEKCL 89
           ++   R   TG  V++ V D     E          + +K ++HPN++   + ++T+  L
Sbjct: 12  VVKLARHVFTGEKVAVKVIDKTKLDEVSRSHLFQEVRCMKLVQHPNVVRLYEVIDTQTKL 191

Query: 90  HIVTEAVTPLGTYLKARAEAGGLKEQELSWGLHQIVKALSFLVNDCNLIHNNV-CMAAVF 148
           +++ E       Y      +GGL+E+       QIV+A+S+  +  +++H ++     VF
Sbjct: 192 YLILELGDGGDMYDYIMRHSGGLEEKLAKRYFRQIVEAISY-CHKLHVVHRDLKPENVVF 368

Query: 149 VDRAGEWKL 157
            ++ G  KL
Sbjct: 369 FEKPGLVKL 395
>00392
          Length = 668

 Score = 33.9 bits (76), Expect = 0.23,   Method: Compositional matrix adjust.
 Identities = 46/180 (25%), Positives = 80/180 (44%), Gaps = 9/180 (5%)
 Frame = +3

Query: 68  LKTLRHPNILAYIDGLE-----TEKCLHIVTEAVT--PLGTYLKARAEAGGLKEQELSWG 120
           LK L+HPNI+ + D  E       K + +VTE +T   L TYLK R +   +K  + +W 
Sbjct: 93  LKELQHPNIVRFFDYWEEHNHRNRKVIILVTELMTSGTLKTYLK-RFKKPNVKILK-NW- 263

Query: 121 LHQIVKALSFL-VNDCNLIHNNVCMAAVFVDR-AGEWKLGGLDYMYSAQGNGGGPPSKGI 178
             Q++K L FL      +IH ++    +F+    G  K+G L  + + +         G 
Sbjct: 264 CRQVLKGLYFLHTRTPPVIHRDLKCDNIFITGPTGSVKIGDLG-LATLKNQSFAKSVIGT 440

Query: 179 PELEQYDPPELADSSSRAVREKWSADMWRLGCLIWEVFNGSLPRAAALRNPGKIPKSLVT 238
           PE   +  PE+ +          + D++  G  + E+ +   P +    N  +I K + +
Sbjct: 441 PE---FMAPEMYEEHYDE-----AVDVYAFGMCMLEMASSEYPYSEC-SNAAQIYKRVTS 593
>04852
          Length = 1462

 Score = 32.7 bits (73), Expect = 0.64,   Method: Compositional matrix adjust.
 Identities = 29/113 (25%), Positives = 51/113 (45%), Gaps = 1/113 (0%)
 Frame = +1

Query: 113 KEQELSWGLHQIVKALSFLVNDCNLIHNNVCMAAVFVDRAGEWKLGGLDYMYSAQGNGGG 172
           ++  LS+   QI + + FL +    IH ++    V V      K+   D+  S  G+   
Sbjct: 322 RKNLLSYAF-QIARGMEFLASR-KCIHRDLAARNVLVTEEHVLKIA--DFGLSRTGDYYK 489

Query: 173 PPSKGIPELEQYDPPELADSSSRAVREKWSADMWRLGCLIWEVFN-GSLPRAA 224
             S G   ++   P  L D     +R    +D+W  G ++WE+F+ G +P A+
Sbjct: 490 KRSGGRLPVKWMAPEALFD-----MRYTTKSDVWSFGVVLWEIFSLGGMPYAS 633
>00394
          Length = 548

 Score = 32.0 bits (71), Expect = 0.92,   Method: Compositional matrix adjust.
 Identities = 26/81 (32%), Positives = 39/81 (48%), Gaps = 7/81 (8%)
 Frame = -2

Query: 31  LHRGRKKATGSAVSIFVYDVKPGAEEQTQVAKAAFKRLKTLRHPNILAYIDGLE-----T 85
           +++G     G AV+      K   + + Q  K   + LK L+HPNI+ + D  E      
Sbjct: 250 VYKGLDTELGVAVAWCELQDKKWNKAERQRFKEEAEMLKELQHPNIVRFFDYWEEHNHRN 71

Query: 86  EKCLHIVTEAVTP--LGTYLK 104
            K + +VTE +T   L TYLK
Sbjct: 70  RKVIILVTELMTSGTLKTYLK 8
>31789
          Length = 676

 Score = 32.0 bits (71), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 26/81 (32%), Positives = 39/81 (48%), Gaps = 7/81 (8%)
 Frame = +2

Query: 31  LHRGRKKATGSAVSIFVYDVKPGAEEQTQVAKAAFKRLKTLRHPNILAYIDGLE-----T 85
           +++G     G AV+      K   + + Q  K   + LK L+HPNI+ + D  E      
Sbjct: 368 VYKGLDTELGVAVAWCELQDKKWNKTERQRFKEEAEMLKELQHPNIVRFFDYWEEHNHRN 547

Query: 86  EKCLHIVTEAVTP--LGTYLK 104
            K + +VTE +T   L TYLK
Sbjct: 548 RKVIILVTELMTSGTLKTYLK 610
>11185
          Length = 473

 Score = 31.6 bits (70), Expect = 1.4,   Method: Compositional matrix adjust.
 Identities = 19/72 (26%), Positives = 32/72 (44%)
 Frame = +1

Query: 148 FVDRAGEWKLGGLDYMYSAQGNGGGPPSKGIPELEQYDPPELADSSSRAVREKWSADMWR 207
           F +   +W +   + M   Q    G P+   PE+ Q   P +             +D+W 
Sbjct: 184 FAEAGDQWNIQSAEEMMK-QVPTSGSPTYMAPEVFQGAEPSIM------------SDLWA 324

Query: 208 LGCLIWEVFNGS 219
           LGC+ +E+F+GS
Sbjct: 325 LGCVFYEMFSGS 360
>12786
          Length = 460

 Score = 29.3 bits (64), Expect = 5.8,   Method: Compositional matrix adjust.
 Identities = 36/148 (24%), Positives = 63/148 (42%), Gaps = 17/148 (11%)
 Frame = -3

Query: 102 YLKARA-EAGGLKEQELSWGLHQIVKALSFLVNDCNLIHNNVCMAAVFVDRAGEWKLGGL 160
           +  ARA +  GL    + +   ++++A+  L N+  +IH+++   A F+  AG  KL   
Sbjct: 452 FFSARAKQEQGLDRMMIKFYWREMLRAVKALHNE-GVIHSDL-KPANFMLVAGNLKLIDF 279

Query: 161 DYMYSAQGNGG--------GPPSKGIPELEQYDPPELADSS----SRAVREKWS----AD 204
               + Q +          G PS   PE       + AD S        + K+     +D
Sbjct: 278 GIANTLQQDKTSVLKDSRVGTPSYMSPEAIMAACDDSADDSMEEDGHRTKPKYKVGVRSD 99

Query: 205 MWRLGCLIWEVFNGSLPRAAALRNPGKI 232
           +W LGC+++ +  G  P      N GK+
Sbjct: 98  VWSLGCILYNMVYGRTPFQHIKNNMGKL 15
>29781
          Length = 498

 Score = 29.3 bits (64), Expect = 5.8,   Method: Compositional matrix adjust.
 Identities = 9/30 (30%), Positives = 23/30 (76%)
 Frame = +1

Query: 121 LHQIVKALSFLVNDCNLIHNNVCMAAVFVD 150
           L++I+  +++++ +C+L + NVC+A +F+ 
Sbjct: 319 LYKIIVCINYIIANCSLTNINVCLAYIFIS 408
>11214
          Length = 1018

 Score = 28.9 bits (63), Expect = 7.8,   Method: Compositional matrix adjust.
 Identities = 30/127 (23%), Positives = 59/127 (46%), Gaps = 16/127 (12%)
 Frame = +3

Query: 351 IPVVVKMFSSTDRAMRIRLLQQMEQFIQYLD----------EPTVNTQIFP---HVTHG- 396
           +P  V++F+++ R +R   L   E+++   D          E  V T + P   HV  G 
Sbjct: 222 VPAHVEIFNNSGRTIRKAKLYLCEEYLLQNDVVPAAPLSRVEVKVQTVVIPLDHHVMPGD 401

Query: 397 -FLDTNPAIREQTVKSMLLLAPKLNEAN-LNVELMKHFARLQAKDDQGPIRCNTTVCLGK 454
            +  + P +R   V +  + +   N  + +NV   +HF RL+ K   G ++C+  V +G 
Sbjct: 402 EWRQSVPGLR---VPNNGVTSASFNHCSFINV---RHFVRLKLKWILGSLKCDVDVTIGT 563

Query: 455 IGSYLSA 461
             ++++ 
Sbjct: 564 SRAHMTV 584
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|24429568|ref|NP_034205.1| dipeptidylpeptidase 6
isoform 2 [Mus musculus]
         (804 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

19310                                                                 116   3e-26
29639                                                                  66   5e-11
14069                                                                  31   2.1  
>19310
          Length = 784

 Score =  116 bits (291), Expect = 3e-26,   Method: Compositional matrix adjust.
 Identities = 70/230 (30%), Positives = 115/230 (50%), Gaps = 4/230 (1%)
 Frame = -3

Query: 548 QILKPATFTDTAHYPLLLVVDGTPG-SQSVTERFEVTWETVLVSSHGAVVVKCDGRGSGF 606
            + +PA     +  P   +    P  + S T   ++   T  +++HG  VV  DGRGS  
Sbjct: 695 HVFRPANSAPASAIPPCCLCTEVPRFNSSQTPSRDLNSATHTLAAHGYAVVVVDGRGSCH 516

Query: 607 QGTKLLQEVRRRLGFLEEKDQMEAVRTMLKE-QYIDKTRVAVFGKDYGGYLSTYILPAKG 665
           +G      V+ RLG +E +DQ+E ++ +     ++D  RVA+ G  YGGYL+   L  + 
Sbjct: 515 RGLGFEGCVKDRLGTIEIEDQVEGLQYVASHFDFVDLNRVAIHGWSYGGYLALMGLAQRP 336

Query: 666 ENQGQTFTCGSALSPITDFKLYASAFSERYLGLHGLDNRAYEMTKLAHRVSALEDQQ--F 723
           +     F    A +P+  +KLY + ++ERYL L  ++   Y    + H +    D++   
Sbjct: 335 D----VFKVAVAGAPVVSWKLYDTGYTERYLSLPQVNVTGYTKGSVLHYLKQFPDEENRL 168

Query: 724 LIIHATADEKIHFQHTAELITQLIKGKANYSLQIYPDESHYFHSVALKQH 773
           LI+H   DE +HF H  +L+T L+K    + LQ+YP+E H   S    +H
Sbjct: 167 LIVHGLIDENVHFHHINKLVTALVKACKPHQLQVYPNERHGIRSHESNEH 18
>29639
          Length = 354

 Score = 66.2 bits (160), Expect = 5e-11,   Method: Compositional matrix adjust.
 Identities = 31/89 (34%), Positives = 55/89 (61%)
 Frame = +2

Query: 617 RRLGFLEEKDQMEAVRTMLKEQYIDKTRVAVFGKDYGGYLSTYILPAKGENQGQTFTCGS 676
           ++LG LE +D ++A   + K+ YID  ++A++G  YGGY++T +L    E     + C  
Sbjct: 44  QKLGTLEVEDTIKATELVSKKHYIDSDKIAIWGWSYGGYVTTSVLGHGTE----LYRCAV 211

Query: 677 ALSPITDFKLYASAFSERYLGLHGLDNRA 705
           +++P+TD+  Y S ++ERY+G    D+ A
Sbjct: 212 SIAPVTDWTYYDSVYTERYMGTPRGDDNA 298
>14069
          Length = 463

 Score = 30.8 bits (68), Expect = 2.1,   Method: Composition-based stats.
 Identities = 17/73 (23%), Positives = 31/73 (42%), Gaps = 8/73 (10%)
 Frame = -2

Query: 560 HYPLLLVVDGTPGSQSVTERFEVTWETVLVSSHGAVVVKCD--------GRGSGFQGTKL 611
           H+P LLV      + +    F+ +W  +   +HG    +C         G    ++G  +
Sbjct: 258 HHPCLLVASSNEVTAAAAVSFDPSWRVLGEVTHGLQYTRCHEILTQSVCGGQGAYEGQSV 79

Query: 612 LQEVRRRLGFLEE 624
            QE RR +  +E+
Sbjct: 78  TQEFRRGVLVVED 40
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6754810|ref|NP_035014.1| N-myc downstream regulated
gene 1 [Mus musculus]
         (394 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

34081                                                                 115   3e-26
29933                                                                  71   8e-13
05631                                                                  35   0.035
02502                                                                  30   2.3  
04461                                                                  29   2.6  
03129                                                                  29   2.6  
13624                                                                  29   4.1  
24808                                                                  28   5.7  
>34081
          Length = 315

 Score =  115 bits (288), Expect = 3e-26,   Method: Composition-based stats.
 Identities = 51/97 (52%), Positives = 70/97 (72%)
 Frame = +2

Query: 55  NRPVILTYHDIGMNHKTCYNPLFNSEDMQEITQHFAVCHVDAPGQQDGAPSFPVGYMYPS 114
           ++P ILT+HDIG+NH TC+   F+  DMQ I +HF V HV+APGQ++ A      ++YP+
Sbjct: 8   SKPAILTFHDIGLNHVTCFQGFFSFSDMQPILRHFCVFHVNAPGQEESALYLKPEFVYPT 187

Query: 115 MDQLAEMLPGVLHQFGLKSVIGMGTGAGAYILTRFAL 151
           MDQLAE +  V+  +GLKS+IG G GAGA +LTR+ L
Sbjct: 188 MDQLAEGVHHVVEHYGLKSIIGFGVGAGANVLTRYEL 298
>29933
          Length = 346

 Score = 70.9 bits (172), Expect = 8e-13,   Method: Composition-based stats.
 Identities = 29/74 (39%), Positives = 48/74 (64%)
 Frame = +3

Query: 110 YMYPSMDQLAEMLPGVLHQFGLKSVIGMGTGAGAYILTRFALNNPEMVEGLVLMNVNPCA 169
           ++YP+M+QLAE +  V+  + LK +IG G GAGA +L R+ L + + ++ LVL+N     
Sbjct: 63  FVYPTMEQLAEAVHAVVEHYDLKCIIGFGVGAGANVLARYELAHHDRLDSLVLVNPLATQ 242

Query: 170 EGWMDWAASKISGW 183
            GW++W   K++ W
Sbjct: 243 AGWVEWGYQKMNSW 284
>05631
          Length = 1440

 Score = 35.4 bits (80), Expect = 0.035,   Method: Compositional matrix adjust.
 Identities = 22/67 (32%), Positives = 35/67 (52%), Gaps = 2/67 (2%)
 Frame = -2

Query: 70  KTCYNPLFNSEDMQEITQHFAVCHVDAPGQQD--GAPSFPVGYMYPSMDQLAEMLPGVLH 127
           K   N +   E++  I +   V H + P  Q    A +F V   +  + Q+AEMLPG+L+
Sbjct: 677 KLSVNTIPGIEEVNMIKEDGQVIHFNNPKVQASLAANTFAV-TGHAEIKQIAEMLPGILN 501

Query: 128 QFGLKSV 134
           Q G +S+
Sbjct: 500 QLGTESL 480
>02502
          Length = 1557

 Score = 29.6 bits (65), Expect = 2.3,   Method: Compositional matrix adjust.
 Identities = 20/73 (27%), Positives = 35/73 (47%), Gaps = 4/73 (5%)
 Frame = +2

Query: 206 EVVHTYRQHILNDMNPSNLHLFISAYNSRRDLEIERPMPGTHTVTLQCPALLVVGD---- 261
           ++ H Y Q+I+ D   +N ++FIS   + + L   +P   +H   L   +  VV D    
Sbjct: 38  KIQHVYFQYIVIDWKLTNPNIFISFCYAHKKLSSSQPTQSSHANKL--*SFTVVPDTNHT 211

Query: 262 NSPAVDAVVECNS 274
           ++PA+     C S
Sbjct: 212 STPAMSTQTVCTS 250
>04461
          Length = 879

 Score = 29.3 bits (64), Expect = 2.6,   Method: Compositional matrix adjust.
 Identities = 11/36 (30%), Positives = 23/36 (63%)
 Frame = -2

Query: 216 LNDMNPSNLHLFISAYNSRRDLEIERPMPGTHTVTL 251
           +N +NPS   L+ + + ++    I++P+P +HT+ L
Sbjct: 788 MNSVNPSFWPLYKNQHTTQEPFNIKKPLPVSHTMVL 681
>03129
          Length = 1112

 Score = 29.3 bits (64), Expect = 2.6,   Method: Compositional matrix adjust.
 Identities = 11/36 (30%), Positives = 23/36 (63%)
 Frame = +1

Query: 216 LNDMNPSNLHLFISAYNSRRDLEIERPMPGTHTVTL 251
           +N +NPS   L+ + + ++    I++P+P +HT+ L
Sbjct: 91  MNSVNPSFWPLYKNQHTTQEPFNIKKPLPVSHTMVL 198
>13624
          Length = 900

 Score = 28.9 bits (63), Expect = 4.1,   Method: Compositional matrix adjust.
 Identities = 18/57 (31%), Positives = 27/57 (47%)
 Frame = -2

Query: 253 CPALLVVGDNSPAVDAVVECNSKLDPTKTTLLKMADCGGLPQISQPAKLAEAFKYFV 309
           C + LV     P+   V  C+  L  TKTT L+ A C     IS+   ++E  + F+
Sbjct: 767 CSSTLVSSCRRPSRKVVRNCSRALSLTKTTPLREASCDM--HISEWWAISELCRTFL 603
>24808
          Length = 1325

 Score = 28.1 bits (61), Expect = 5.7,   Method: Compositional matrix adjust.
 Identities = 13/34 (38%), Positives = 20/34 (58%)
 Frame = +3

Query: 341 RSRSHTSEGPRSRSHTSEGSRSRSHTSEDARLNI 374
           R++ HT    R+R+HT   +R+R+HT     L I
Sbjct: 87  RTKKHTDTXRRARAHTHTHTRARTHTHTYIHLFI 188
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6755140|ref|NP_035278.1| serine/threonine protein
phosphatase with EF-hand motifs 2 [Mus musculus]
         (757 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

01173                                                                 116   3e-26
06264                                                                 115   9e-26
19040                                                                 114   1e-25
08242                                                                 102   5e-22
18336                                                                  86   7e-17
25536                                                                  79   5e-15
06084                                                                  72   6e-13
30980                                                                  50   5e-06
36367                                                                  47   4e-05
04295                                                                  45   7e-05
05237                                                                  40   0.003
14594                                                                  40   0.004
04697                                                                  39   0.009
26849                                                                  39   0.009
21146                                                                  37   0.038
26610                                                                  32   0.76 
20251                                                                  32   1.3  
26019                                                                  30   3.2  
22490                                                                  30   3.9  
32935                                                                  30   4.1  
>01173
          Length = 2619

 Score =  116 bits (290), Expect = 3e-26,   Method: Compositional matrix adjust.
 Identities = 59/136 (43%), Positives = 85/136 (62%)
 Frame = -1

Query: 174  VTVCGDLHGQLDDLIFIFYKNGLPSPERAYVFNGDFVDRGKDSVEVLMVLFAFMLVYPKE 233
            + +CGD+HGQ  DL+ +F   G P PE  Y+F GD+VDRGK S+E + +L A+ + YP+ 
Sbjct: 2520 LKICGDIHGQYYDLLRLFEYGGFP-PESNYLFLGDYVDRGKQSLETICLLLAYKIKYPEN 2344

Query: 234  FHLNRGNHEDHLVNLRYGFTKEVMHKYKIHGKKILRTLQDVFCWLPLATLVDEKVLVLHG 293
            F L RGNHE   +N  YGF  E   +Y I   K+ +T  D F  LP+A ++DEK+   HG
Sbjct: 2343 FFLLRGNHECASINRIYGFYDECKRRYNI---KLWKTFTDCFNCLPIAAIIDEKIFCCHG 2173

Query: 294  GVSDKTDLELLAKLDR 309
            G+S   DL+ + ++ R
Sbjct: 2172 GLS--PDLQSMEQIRR 2131

 Score = 62.8 bits (151), Expect = 5e-10,   Method: Compositional matrix adjust.
 Identities = 37/115 (32%), Positives = 60/115 (52%), Gaps = 2/115 (1%)
 Frame = -1

Query: 421  LAPDADCVADGGGVLEPT--PEEWKQVVDILWSDPAAQEGCKANAVRGGGCYFGPDVTER 478
            L+PD   +     ++ PT  P++   + D+LWSDP  +        RG    FG +V  +
Sbjct: 2169 LSPDLQSMEQIRRIMRPTDVPDQ-GLLCDLLWSDPDKETMGWGENDRGVSFTFGAEVVAK 1993

Query: 479  LMEKYKLQLLIRSHECKPEGYEFCHNRKVLTIFSASNYYEVGSNRGAYVKLGPAL 533
             + K+ L L+ R+H+   +GYEF   R+++T+FSA NY     N GA + +   L
Sbjct: 1992 FLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETL 1828
>06264
          Length = 999

 Score =  115 bits (287), Expect = 9e-26,   Method: Compositional matrix adjust.
 Identities = 58/136 (42%), Positives = 85/136 (62%)
 Frame = -3

Query: 174 VTVCGDLHGQLDDLIFIFYKNGLPSPERAYVFNGDFVDRGKDSVEVLMVLFAFMLVYPKE 233
           + +CGD+HGQ  DL+ +F   G P PE  Y+F GD+VDRG+ S+E + +L A+ + YP+ 
Sbjct: 922 LKICGDIHGQYYDLLRLFEYGGFP-PESNYLFLGDYVDRGRQSLETICLLLAYKIKYPEN 746

Query: 234 FHLNRGNHEDHLVNLRYGFTKEVMHKYKIHGKKILRTLQDVFCWLPLATLVDEKVLVLHG 293
           F L RGNHE   +N  YGF  E   +Y I   K+ +T  D F  LP+A ++DEK+   HG
Sbjct: 745 FFLLRGNHECASINRIYGFYDECKRRYNI---KLWKTFTDCFNCLPIAAIIDEKIFCCHG 575

Query: 294 GVSDKTDLELLAKLDR 309
           G+S   DL+ + ++ R
Sbjct: 574 GLS--PDLQSMEQIRR 533

 Score = 63.2 bits (152), Expect = 4e-10,   Method: Compositional matrix adjust.
 Identities = 37/115 (32%), Positives = 61/115 (53%), Gaps = 2/115 (1%)
 Frame = -3

Query: 421 LAPDADCVADGGGVLEPT--PEEWKQVVDILWSDPAAQEGCKANAVRGGGCYFGPDVTER 478
           L+PD   +     ++ PT  P++   + D+LWSDP  +      + RG    FG +V  +
Sbjct: 571 LSPDLQSMEQIRRIMRPTDVPDQ-GLLCDLLWSDPDKETMGWGESDRGVSFTFGAEVVAK 395

Query: 479 LMEKYKLQLLIRSHECKPEGYEFCHNRKVLTIFSASNYYEVGSNRGAYVKLGPAL 533
            + K+ L L+ R+H+   +GYEF   R+++T+FSA NY     N GA + +   L
Sbjct: 394 FLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETL 230
>19040
          Length = 452

 Score =  114 bits (286), Expect = 1e-25,   Method: Composition-based stats.
 Identities = 54/123 (43%), Positives = 77/123 (62%)
 Frame = -3

Query: 174 VTVCGDLHGQLDDLIFIFYKNGLPSPERAYVFNGDFVDRGKDSVEVLMVLFAFMLVYPKE 233
           + +CGD+HGQ  DL+ +F   G P P   Y+F GD+VDRGK S+E + +L A+ + YP+ 
Sbjct: 381 LIICGDIHGQYTDLLRLFEYGGFP-PAANYLFLGDYVDRGKQSLETICLLLAYKIKYPEN 205

Query: 234 FHLNRGNHEDHLVNLRYGFTKEVMHKYKIHGKKILRTLQDVFCWLPLATLVDEKVLVLHG 293
           F L RGNHE   +N  YGF  E   +Y +   K+ +T  D F  LP+A ++DEK+   HG
Sbjct: 204 FFLLRGNHECASINRIYGFYDECKRRYNV---KLWKTFTDCFNCLPVAAIIDEKIFCCHG 34

Query: 294 GVS 296
           G+S
Sbjct: 33  GLS 25
>08242
          Length = 3368

 Score =  102 bits (254), Expect = 5e-22,   Method: Compositional matrix adjust.
 Identities = 61/158 (38%), Positives = 87/158 (55%), Gaps = 1/158 (0%)
 Frame = -1

Query: 157  LAQLPNINRVSTCYSEEVTVCGDLHGQLDDLIFIFYKNGLPSPERAYVFNGDFVDRGKDS 216
            L +  N+ RV +     VTVCGD+HGQ  DL  +F K G   P+  Y+F GDFVDRG  S
Sbjct: 3362 LVEESNVQRVDS----PVTVCGDIHGQFYDLKELF-KVGGDVPDTNYLFMGDFVDRGFYS 3198

Query: 217  VEVLMVLFAFMLVYPKEFHLNRGNHEDHLVNLRYGFTKEVMHKYKIHGKKILRTLQDVFC 276
            VE  ++L A  + YP    L RGNHE   +   YGF  E + KY      + R   ++F 
Sbjct: 3197 VETFLLLLALKVRYPDRITLIRGNHESRQITQVYGFYDECLRKYG--SITVWRYCTEIFD 3024

Query: 277  WLPLATLVDEKVLVLHGGVSDKTD-LELLAKLDRHKIV 313
            +L L+ ++D K+  +HGG+S     L+ +  +DR + V
Sbjct: 3023 YLSLSAIIDGKIFCVHGGLSPSIQTLDQIRSIDRKQEV 2910

 Score = 58.9 bits (141), Expect = 7e-09,   Method: Compositional matrix adjust.
 Identities = 33/98 (33%), Positives = 50/98 (51%)
 Frame = -1

Query: 445  VVDILWSDPAAQEGCKANAVRGGGCYFGPDVTERLMEKYKLQLLIRSHECKPEGYEFCHN 504
            + D+LWSDP   +G   +  RG G  FG DV  +      + L+ R+H+   EGY++  N
Sbjct: 2894 MCDLLWSDPEDMQGWGVSP-RGAGYLFGSDVVSQFNAANXIDLICRAHQLVMEGYKWHFN 2718

Query: 505  RKVLTIFSASNYYEVGSNRGAYVKLGPALTPHIVQYQA 542
              VLT++SA NY     N  A ++L   L      ++A
Sbjct: 2717 ETVLTVWSAPNYCYRCGNVAAILELDEHLQRDFTIFEA 2604
>18336
          Length = 465

 Score = 85.5 bits (210), Expect = 7e-17,   Method: Composition-based stats.
 Identities = 39/77 (50%), Positives = 52/77 (67%)
 Frame = +2

Query: 176 VCGDLHGQLDDLIFIFYKNGLPSPERAYVFNGDFVDRGKDSVEVLMVLFAFMLVYPKEFH 235
           +CGD+HGQ  DL+ +F   G P PE  Y+F GD+VDRGK S+E + +L A+ + YP+ F 
Sbjct: 104 ICGDIHGQYYDLLRLFEYGGFP-PESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFF 280

Query: 236 LNRGNHEDHLVNLRYGF 252
           L RGNHE   +N  YGF
Sbjct: 281 LLRGNHECASINRIYGF 331
>25536
          Length = 486

 Score = 79.3 bits (194), Expect = 5e-15,   Method: Compositional matrix adjust.
 Identities = 47/129 (36%), Positives = 69/129 (53%)
 Frame = +1

Query: 132 VEAFRLRQQLHARYVLNLLYETRKHLAQLPNINRVSTCYSEEVTVCGDLHGQLDDLIFIF 191
           +E     +QL    V  L  + ++ L++  N+  V       VTVCGD+HGQ  DL+ +F
Sbjct: 82  IEQLNDCKQLSENQVKTLCEKAKEILSKESNVQEVKC----PVTVCGDVHGQFHDLMELF 249

Query: 192 YKNGLPSPERAYVFNGDFVDRGKDSVEVLMVLFAFMLVYPKEFHLNRGNHEDHLVNLRYG 251
            + G  SP+  Y+F GD+VDRG  SVE + +L A  + +     + RGNHE   +   YG
Sbjct: 250 -RIGGKSPDTNYLFMGDYVDRGYYSVETVSLLVALKVRFRDRITILRGNHESRQITQVYG 426

Query: 252 FTKEVMHKY 260
           F  E + KY
Sbjct: 427 FYDECLRKY 453
>06084
          Length = 1739

 Score = 72.4 bits (176), Expect = 6e-13,   Method: Compositional matrix adjust.
 Identities = 49/132 (37%), Positives = 70/132 (53%), Gaps = 1/132 (0%)
 Frame = -2

Query: 181  HGQLDDLIFIFYKNGLPSPERAYVFNGDFVDRGKDSVEVLMVLFAFMLVYPKEFHLNRGN 240
            HGQ  DL+ +F K G   P+  YVF GDFVDRG  S+E   +L      +P +  L RGN
Sbjct: 1738 HGQFYDLMELF-KTGGEMPDTNYVFMGDFVDRGYFSLETFTLLLTLKAKWPDKIVLLRGN 1562

Query: 241  HEDHLVNLRYGFTKEVMHKYKIHGKKILRTLQDVFCWLPLATLVDEKVLVLHGGVS-DKT 299
            HE   +   YGF  E   KY        R    VF  L +A ++DE +L +HGG+S D  
Sbjct: 1561 HESRQITQIYGFYDECQTKYG--NANAWRYCCRVFDLLTIAAIIDECILCVHGGLSPDIK 1388

Query: 300  DLELLAKLDRHK 311
             ++ +  ++R++
Sbjct: 1387 TIDQIRTIERNQ 1352

 Score = 53.5 bits (127), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 28/76 (36%), Positives = 45/76 (59%), Gaps = 1/76 (1%)
 Frame = -2

Query: 447  DILWSDPAAQEGCKANAVRGGGCYFGPDVTERLMEKYKLQLLIRSHECKPEGYEFCHNRK 506
            D++WSDP   +   A + RG G  FG  VT   +    L+L+ R+H+   EGY++  + K
Sbjct: 1324 DLVWSDPEDVDT-WAMSPRGAGWLFGAKVTAEFVASNNLKLICRAHQLVHEGYKYMFDEK 1148

Query: 507  VLTIFSASNY-YEVGS 521
            ++T++SA NY Y  G+
Sbjct: 1147 LVTVWSAPNYCYRCGN 1100
>30980
          Length = 765

 Score = 49.7 bits (117), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 24/56 (42%), Positives = 35/56 (62%)
 Frame = +3

Query: 485 LQLLIRSHECKPEGYEFCHNRKVLTIFSASNYYEVGSNRGAYVKLGPALTPHIVQY 540
           L L+ R+H+   EGY +CH+R V+TIFSA NY     N+ A ++L  AL    +Q+
Sbjct: 24  LTLISRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDALKYSFLQF 191
>36367
          Length = 827

 Score = 46.6 bits (109), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 32/104 (30%), Positives = 48/104 (46%), Gaps = 14/104 (13%)
 Frame = +1

Query: 438 TPEEWKQVVDILWSDPAA--------------QEGCKANAVRGGGCYFGPDVTERLMEKY 483
           +P  W    +ILWSDP +                G   N+ RG   +F  +     +E+ 
Sbjct: 94  SPMAW----EILWSDPISVDLVSPEVLKDMKEHHGFTFNSRRGTAHFFSCNALLAFLERN 261

Query: 484 KLQLLIRSHECKPEGYEFCHNRKVLTIFSASNYYEVGSNRGAYV 527
            L  +IR+HE +  G++     K+LT+FS+S Y   GSN  A V
Sbjct: 262 GLSHVIRAHEVQEVGFQVQQQGKLLTVFSSSRYCG-GSNEAACV 390
>04295
          Length = 748

 Score = 45.4 bits (106), Expect = 7e-05,   Method: Compositional matrix adjust.
 Identities = 20/60 (33%), Positives = 34/60 (56%)
 Frame = -1

Query: 474 DVTERLMEKYKLQLLIRSHECKPEGYEFCHNRKVLTIFSASNYYEVGSNRGAYVKLGPAL 533
           DV  + + ++ L L+ R+H+   +GYEF   R+++T+FSA NY     N G  + +   L
Sbjct: 745 DVVSKFLNRHDLDLITRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDETL 566
>05237
          Length = 472

 Score = 40.4 bits (93), Expect = 0.003,   Method: Composition-based stats.
 Identities = 23/85 (27%), Positives = 43/85 (50%), Gaps = 1/85 (1%)
 Frame = +3

Query: 661 LETIFRIIDSDHSGFISLDEFRQTWKLFSSHMSIDITDDGICDLARSIDFNKDGHIDINE 720
           L   FR+ D D +GFIS  E R       +++   +TD+ + ++ R  D + DG ++  E
Sbjct: 33  LREAFRVFDKDGNGFISASELRHVM----TNLGEKLTDEEVDEMIREADIDGDGQVNYEE 200

Query: 721 FLEAFRLV-EQSCLEGHASACLQST 744
           F++       ++ L+   + CL S+
Sbjct: 201 FVKMMTTK*SKTFLQTIIAMCLHSS 275
>14594
          Length = 1014

 Score = 40.0 bits (92), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 41/193 (21%), Positives = 84/193 (43%), Gaps = 15/193 (7%)
 Frame = +3

Query: 558 VEESALRALRQKLFAHSSDLLVEFRKR----DPDESGVITLSDWATAVESVLHLGLPWRM 613
           V  S L   ++ +   + + + EF++     D D  G IT S+  T + S L        
Sbjct: 378 VRHSLLIMSQEHIVTLTDEQVAEFKEAFSLFDKDGDGTITTSELGTVMRS-LGQNPTENE 554

Query: 614 LRPQL--VNSSADNVLEYRSWLDSLAKEQLSRENIQSSLLEKLYRNRSNLETIFRIIDSD 671
           L+  +  V++  +  +++  +L  +A+ ++   + +  L E            FR+ D D
Sbjct: 555 LQDMINEVDADGNGTIDFEEFLHMMAR-KMKDTDCEEELREA-----------FRVFDKD 698

Query: 672 HSGFISLDEFRQTWKLFSSHMSIDITDDGICDLARSIDFNKDGHIDINEFL--------- 722
            +G+IS  E R       +++   +TD+ + ++ +  D + DG ++  EF+         
Sbjct: 699 GNGYISAAELRHVM----TNLGEKLTDEEVDEMIKEADLDGDGMVNYEEFVTMMTAK*PS 866

Query: 723 EAFRLVEQSCLEG 735
           E  RL+  S + G
Sbjct: 867 EGTRLLHHSLING 905
>04697
          Length = 559

 Score = 38.9 bits (89), Expect = 0.009,   Method: Compositional matrix adjust.
 Identities = 15/59 (25%), Positives = 36/59 (61%)
 Frame = +1

Query: 665 FRIIDSDHSGFISLDEFRQTWKLFSSHMSIDITDDGICDLARSIDFNKDGHIDINEFLE 723
           F+ +D  + GF+++++ R+ +K     M   +T+D + D+   +D +++  +D+ EFL+
Sbjct: 379 FKSLDYQNKGFVTVNDLRRYFK----KMGEKVTEDQLHDILSEVDLSRNAQVDLGEFLQ 543
>26849
          Length = 649

 Score = 38.5 bits (88), Expect = 0.009,   Method: Composition-based stats.
 Identities = 29/97 (29%), Positives = 52/97 (53%), Gaps = 7/97 (7%)
 Frame = +2

Query: 633 LDSLAKEQLS----RENIQSSLLEKLYRNRSN---LETIFRIIDSDHSGFISLDEFRQTW 685
           L++L++ +L+    +++I    L+ L R  +    L   FR++D D S  +SL+EF++  
Sbjct: 68  LENLSRRELANGLEKDSIYKLRLQCLSRGPTGILGLARAFRVMDKDGSKVLSLEEFKKG- 244

Query: 686 KLFSSHMSIDITDDGICDLARSIDFNKDGHIDINEFL 722
                 M IDI +  I D+    D + +G I++ EFL
Sbjct: 245 ---ILDMHIDINEADIEDMFYRFDNDGNGTINMTEFL 346
>21146
          Length = 408

 Score = 36.6 bits (83), Expect = 0.038,   Method: Composition-based stats.
 Identities = 18/47 (38%), Positives = 26/47 (55%)
 Frame = +3

Query: 447 DILWSDPAAQEGCKANAVRGGGCYFGPDVTERLMEKYKLQLLIRSHE 493
           D+LWSDP  + G   +  RG G  FG D++E       L L+ R+H+
Sbjct: 129 DLLWSDPDDRGGWGISP-RGAGYTFGQDISETFNHSNGLTLISRAHQ 266
>26610
          Length = 455

 Score = 32.3 bits (72), Expect = 0.76,   Method: Compositional matrix adjust.
 Identities = 33/139 (23%), Positives = 58/139 (41%)
 Frame = +3

Query: 585 DPDESGVITLSDWATAVESVLHLGLPWRMLRPQLVNSSADNVLEYRSWLDSLAKEQLSRE 644
           D D  G I  S+  TA+ S+ H+           V  S    L  ++ ++   K  ++R 
Sbjct: 72  DTDNDGKIAASEVGTAIRSLGHV-----------VTDSDLRRLLSKAGIEPHGKVDMNRF 218

Query: 645 NIQSSLLEKLYRNRSNLETIFRIIDSDHSGFISLDEFRQTWKLFSSHMSIDITDDGICDL 704
                 L+ +   +  L+  F  ID + SGF+   E R       +HM   ITD+    L
Sbjct: 219 RQLVQPLQGVNYTK-QLDEAFNTIDKEGSGFVMATELRHLL----THMGDRITDEEFNAL 383

Query: 705 ARSIDFNKDGHIDINEFLE 723
              ++ + +G +   EF++
Sbjct: 384 LEELEVDSNGRVRRKEFVQ 440
>20251
          Length = 2203

 Score = 31.6 bits (70), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 18/56 (32%), Positives = 32/56 (57%), Gaps = 1/56 (1%)
 Frame = +1

Query: 271 LQDVFCWLPLATLVDEKVL-VLHGGVSDKTDLELLAKLDRHKIVSTMRCKTRKESE 325
           L  VFC++ L  L+D  +L + +GG + K ++ LL  ++  KI +   CK +K  +
Sbjct: 886 LYKVFCYILLMLLIDGNILEIYYGGHTKKKEMWLLV-VNGGKIENKYLCKIKKNYD 1050
>26019
          Length = 1561

 Score = 30.0 bits (66), Expect = 3.2,   Method: Compositional matrix adjust.
 Identities = 28/98 (28%), Positives = 47/98 (47%), Gaps = 7/98 (7%)
 Frame = +2

Query: 665 FRIIDSDHSGFISLDEFRQTWKLFSSHMSIDITDDGICDLARSID-FNKDGH--IDINEF 721
           FR +D D+SG +S+DEF    +L  + +           + R ID F+ DG+  +D  EF
Sbjct: 116 FRKLDLDNSGSLSIDEFMSLPELQQNPL-----------VQRVIDIFDTDGNGEVDFKEF 262

Query: 722 LEAFRLVEQSCLEGHASACLQST----DTAESGHSSPG 755
           +E    + Q  ++G   + L+      D  + G+ S G
Sbjct: 263 IEG---ISQFSVKGDKESKLRFAFKIYDMDKDGYISNG 367
>22490
          Length = 743

 Score = 30.0 bits (66), Expect = 3.9,   Method: Composition-based stats.
 Identities = 13/48 (27%), Positives = 27/48 (56%)
 Frame = -1

Query: 689 SSHMSIDITDDGICDLARSIDFNKDGHIDINEFLEAFRLVEQSCLEGH 736
           + HM  D  +D + ++ R  D +KDG++D  EF++  +  ++   + H
Sbjct: 503 APHMDEDELEDIVDEILREDDLDKDGYVDYTEFMKGQKRRDEQIRQRH 360
>32935
          Length = 1188

 Score = 29.6 bits (65), Expect = 4.1,   Method: Compositional matrix adjust.
 Identities = 19/45 (42%), Positives = 21/45 (46%)
 Frame = -1

Query: 417 ESLPLAPDADCVADGGGVLEPTPEEWKQVVDILWSDPAAQEGCKA 461
           E   L   A  VADGG V E  PEE K+      +DP   E C A
Sbjct: 747 EGAGLDDAAGTVADGGSVGEWEPEEGKKNSTSRAADPGLSEPCTA 613
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|151101194|ref|NP_080595.2| coiled-coil domain
containing 2 [Mus musculus]
         (600 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

33194                                                                  75   5e-26
05922                                                                  94   5e-23
13576                                                                  31   1.7  
07785                                                                  30   3.3  
35697                                                                  29   5.2  
>33194
          Length = 447

 Score = 74.7 bits (182), Expect(2) = 5e-26,   Method: Compositional matrix adjust.
 Identities = 35/71 (49%), Positives = 49/71 (69%)
 Frame = +2

Query: 343 LDMDLEEHQGEMNQKYKELKKREENMDAFIETFEETKNQELERKAQIEASIITLLEHCSR 402
           L   L   QGE NQKYKELKKRE++MD F+ TF+E K QEL + A++E ++  LLE+ SR
Sbjct: 119 LTWTLRRXQGERNQKYKELKKREQSMDEFLSTFDENKVQELTKIAEVEGNVTALLENISR 298

Query: 403 NINRMKQISSI 413
           N+ R   + ++
Sbjct: 299 NMGRFTNLPTL 331

 Score = 62.0 bits (149), Expect(2) = 5e-26,   Method: Compositional matrix adjust.
 Identities = 32/44 (72%), Positives = 38/44 (86%)
 Frame = +1

Query: 304 ERERLLKQVKEDNQEIASMERQLTDIKEKINQFSEEIRQLDMDL 347
           ERERLLKQVKEDNQEIASMERQ  + +EKI+Q  +EI QLD+D+
Sbjct: 1   ERERLLKQVKEDNQEIASMERQAKEQQEKIDQMRDEITQLDLDI 132
>05922
          Length = 942

 Score = 94.0 bits (232), Expect(2) = 5e-23,   Method: Compositional matrix adjust.
 Identities = 42/84 (50%), Positives = 58/84 (69%)
 Frame = -1

Query: 504 ERTVLSTHRNAFKKIMEKLTSDYDTLKRQLQDNETHAQLTNLERKWQHLEQNNFVMKEFI 563
           +R +L   R  FKK M+ LT  Y+ LK QL +NET+ QL+NLE+KWQH EQNNF MKEFI
Sbjct: 774 DRVILQKRRECFKKQMQNLTLKYEGLKTQLNENETYTQLSNLEKKWQHHEQNNFSMKEFI 595

Query: 564 ATKSQESDYQPVIKNVMKQIAEYN 587
           + ++ E DY P+ + V   + ++N
Sbjct: 594 SARTMECDYTPISRRVYSSLDDFN 523

 Score = 32.3 bits (72), Expect(2) = 5e-23,   Method: Compositional matrix adjust.
 Identities = 18/39 (46%), Positives = 23/39 (58%)
 Frame = -3

Query: 448 RLQLDLQKMELLESKMTEEQQSLKNKIKQMTADLETYSD 486
           +LQ DL KM   E K+ EEQ  L+ KIK M  +L  + D
Sbjct: 940 KLQQDLSKMNGFEEKLREEQVILQQKIKDMEKELAVFGD 824
>13576
          Length = 579

 Score = 30.8 bits (68), Expect = 1.7,   Method: Compositional matrix adjust.
 Identities = 21/74 (28%), Positives = 39/74 (52%), Gaps = 10/74 (13%)
 Frame = +3

Query: 320 ASMERQLTDIKEKINQFSEEIRQLDM---DLEEHQGEMNQKYKE-------LKKREENMD 369
            + ERQ+ ++++KI    ++  + DM   +L EHQGE+++  +E       L+   + +D
Sbjct: 174 GTFERQMAELRKKIKSTIQDANECDMEIRELREHQGELSKSLEEKQVNCQTLQGSADTLD 353

Query: 370 AFIETFEETKNQEL 383
             IE   E K + L
Sbjct: 354 GDIEQMVEIKQKNL 395
>07785
          Length = 1179

 Score = 29.6 bits (65), Expect = 3.3,   Method: Compositional matrix adjust.
 Identities = 26/91 (28%), Positives = 45/91 (49%), Gaps = 1/91 (1%)
 Frame = +3

Query: 255 NMKKESLETEIAHSQVKQEAVLLYEKLYELES-HRDQMIAEDKSMGSPMEERERLLKQVK 313
           N+K  ++E   A ++  QE     E    LE+ H DQ + ED         R  L K+++
Sbjct: 183 NLK--TIEDNQASARYLQEVAASLEARLSLENKHLDQFLIED---------RPALFKKIQ 329

Query: 314 EDNQEIASMERQLTDIKEKINQFSEEIRQLD 344
             ++ +  ME QLT I E+++Q  + +  +D
Sbjct: 330 IQDELLDHMEAQLTAIGEQLDQLWDMVNVID 422
>35697
          Length = 506

 Score = 29.3 bits (64), Expect = 5.2,   Method: Composition-based stats.
 Identities = 17/41 (41%), Positives = 21/41 (51%)
 Frame = -3

Query: 442 LTSDSQRLQLDLQKMELLESKMTEEQQSLKNKIKQMTADLE 482
           L  D +RLQLD      L  K+ E +  L  K   MTAD+E
Sbjct: 498 LRKDMERLQLDGLPPNTLNEKIAELETRLAEKKSAMTADVE 376
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|50053703|ref|NP_758465.2| protein phosphatase 1,
regulatory subunit 9B [Mus musculus]
         (817 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

27345                                                                 115   5e-26
29705                                                                  47   2e-05
15076                                                                  31   2.1  
37239                                                                  29   9.4  
>27345
          Length = 496

 Score =  115 bits (289), Expect = 5e-26,   Method: Compositional matrix adjust.
 Identities = 54/77 (70%), Positives = 68/77 (88%)
 Frame = +3

Query: 523 KLGIFVKTVTEGGAAHRDGRIQVNDLLVEVDGTSLVGVTQSFAASVLRNTKGRVRFMIGR 582
           KLGIF+KT+T+GGAA +DGRIQVND ++EVDG SLVGVTQ++AASVLRNT G+V F IGR
Sbjct: 18  KLGIFIKTLTDGGAAQKDGRIQVNDQIIEVDGKSLVGVTQAYAASVLRNTSGQVTFHIGR 197

Query: 583 ERPGEQSEVAQLIQQTL 599
           ++   +SEVA+LIQQ+L
Sbjct: 198 DKDPAKSEVARLIQQSL 248
>29705
          Length = 674

 Score = 47.4 bits (111), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 25/58 (43%), Positives = 35/58 (60%)
 Frame = -1

Query: 525 GIFVKTVTEGGAAHRDGRIQVNDLLVEVDGTSLVGVTQSFAASVLRNTKGRVRFMIGR 582
           GIF+  V EGG+A +DGRI V D L+ V+  +L  VT   A + L++T   VR  I +
Sbjct: 362 GIFITKVIEGGSAEQDGRIAVMDRLLAVNEHNLEDVTHEEAVAALKSTGDVVRLTIAK 189

 Score = 37.0 bits (84), Expect = 0.032,   Method: Composition-based stats.
 Identities = 17/49 (34%), Positives = 28/49 (57%)
 Frame = -2

Query: 534 GGAAHRDGRIQVNDLLVEVDGTSLVGVTQSFAASVLRNTKGRVRFMIGR 582
           GGAA  DGR+++ND++V+V    +   T + A   L+ +  RV   + R
Sbjct: 622 GGAAAEDGRLRLNDIIVKVGTEDVSNTTHTAAVDALKRSGNRVYLQVKR 476
>15076
          Length = 2760

 Score = 30.8 bits (68), Expect = 2.1,   Method: Compositional matrix adjust.
 Identities = 14/36 (38%), Positives = 21/36 (58%)
 Frame = +1

Query: 145  QETRKLFERSVPAASGGDKEAVARRLLRQERAGLQD 180
            Q+   LFE SVP   G     +A RL++ ER+ ++D
Sbjct: 1960 QQCSGLFEVSVPVFDGDVTSKLAARLMKSERSKIKD 2067
>37239
          Length = 453

 Score = 28.9 bits (63), Expect = 9.4,   Method: Composition-based stats.
 Identities = 12/25 (48%), Positives = 19/25 (76%)
 Frame = -3

Query: 525 GIFVKTVTEGGAAHRDGRIQVNDLL 549
           GI+++ +T GGAA +DG++ V D L
Sbjct: 76  GIYIRHITIGGAAAKDGQLAVGDEL 2
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6680137|ref|NP_032219.1| guanylate kinase 1 [Mus
musculus]
         (198 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

13641                                                                 113   5e-26
27435                                                                 101   2e-22
35802                                                                  87   4e-18
29974                                                                  87   4e-18
11512                                                                  84   5e-17
37412                                                                  48   2e-06
38795                                                                  30   0.93 
20270                                                                  28   2.6  
15740                                                                  27   7.7  
>13641
          Length = 2081

 Score =  113 bits (282), Expect = 5e-26,   Method: Compositional matrix adjust.
 Identities = 71/198 (35%), Positives = 110/198 (55%), Gaps = 8/198 (4%)
 Frame = +2

Query: 5   RPVVLSGPSGAGKSTLLKKLFQEHSSIFGFSVSHTTRNPRPGEEDGKDYYFVTREMMQRD 64
           RP+VL G  G G++ L ++L   +   F   V +TTR  +P EEDGK+Y+FV+RE M+  
Sbjct: 563 RPIVLIGAPGIGRNELKRRLKASNPMHFLEVVPYTTRTKKPFEEDGKEYHFVSREDMEES 742

Query: 65  IAAGDFIEHAEFSGNLYGTSKEAVRAVQAMNRICVLDVDLQGVRSIKKTDLCPIYIFVQP 124
           I A  F+E+ E  G+LYGTS E+++ V A  ++C+L    Q ++ ++  +L P  IF++ 
Sbjct: 743 IIAQKFVEYGEHHGHLYGTSVESIKQVIAAGKVCLLTPHTQALKFLRTYELKPYVIFIKS 922

Query: 125 PSLDVL-EQRL--RLRNTETEE----SLAKRLAAARTDMESSKEPG-LFDLVIINDDLDK 176
           P+L+ L E R+  R R TE +     S+ +    A T     +  G +FD+ I+ND L  
Sbjct: 923 PTLEKLKESRMPARARATEADSIRPFSIEELEEMAETSRRLEERYGHVFDITIVNDSLTD 1102

Query: 177 AYATLKQALSEEIKKAQG 194
           A   L    S+  K   G
Sbjct: 1103ATTELLMVASK*RKNHSG 1156
>27435
          Length = 456

 Score =  101 bits (251), Expect = 2e-22,   Method: Compositional matrix adjust.
 Identities = 49/141 (34%), Positives = 87/141 (61%), Gaps = 1/141 (0%)
 Frame = +1

Query: 47  EEDGKDYYFVTREMMQRDIAAGDFIEHAEFSGNLYGTSKEAVRAVQAMNRICVLDVDLQG 106
           E +GKDY+F+TR + + D+ +G F+E+ EF GNLYGT+ EAVR V    RIC+L++  + 
Sbjct: 1   EHNGKDYHFITRAVFEADMLSGKFVEYGEFQGNLYGTTVEAVRQVIQQGRICILNLGPES 180

Query: 107 VRSIKKTDLCPIYIFVQPPSLDVLEQ-RLRLRNTETEESLAKRLAAARTDMESSKEPGLF 165
           ++++++T+L P  IF+ PP ++ L Q ++ L      +   K +     +ME       F
Sbjct: 181 LKNLRETELKPYIIFISPPXMEKLRQLQMALGKPRPTDDQVKEVIERGREMEEMYS-HYF 357

Query: 166 DLVIINDDLDKAYATLKQALS 186
           D +++N +L++A+  L Q ++
Sbjct: 358 DYILVNMELNRAFDELLQEIN 420
>35802
          Length = 571

 Score = 87.0 bits (214), Expect = 4e-18,   Method: Compositional matrix adjust.
 Identities = 50/151 (33%), Positives = 83/151 (54%), Gaps = 4/151 (2%)
 Frame = +1

Query: 47  EEDGKDYYFVTREMMQRDIAAGDFIEHAEFSGNLYGTSKEAVRAVQAMNRICVLDVDLQG 106
           E  G+DY+F +R M + D+ +G F+E+ EF  NLYGTS EAVR V    R+C+L+++ + 
Sbjct: 1   EMTGRDYHFTSRSMFEADMLSGKFLEYGEFQSNLYGTSVEAVRQVILQGRVCLLNLEPES 180

Query: 107 VRSIKKTDLCPIYIFVQPPSLDVLEQRL----RLRNTETEESLAKRLAAARTDMESSKEP 162
           ++ +++TDL P   FV PP+++ L Q      ++R T+ +            DM      
Sbjct: 181 LKILRETDLKPYTXFVCPPNMEKLRQLHIAMGKIRPTDDQLKTVMDKGREMEDMYGH--- 351

Query: 163 GLFDLVIINDDLDKAYATLKQALSEEIKKAQ 193
             FD  ++N D+D++     Q L  EI + +
Sbjct: 352 -FFDYKLVNMDVDRSV----QELMAEINRIE 429
>29974
          Length = 344

 Score = 87.0 bits (214), Expect = 4e-18,   Method: Compositional matrix adjust.
 Identities = 45/107 (42%), Positives = 63/107 (58%), Gaps = 1/107 (0%)
 Frame = +1

Query: 24  LFQEHSSIFGFSVSHTTRNPRPGEEDGKDYYFVT-REMMQRDIAAGDFIEHAEFSGNLYG 82
           L  E    FG  + HTTR  R  EE G+DY+FV+ RE M+RDI    FIE   ++ NLYG
Sbjct: 10  LISEFPDKFGSCIPHTTRERRTNEEPGQDYHFVSSREQMERDIQNHLFIEAGVYNDNLYG 189

Query: 83  TSKEAVRAVQAMNRICVLDVDLQGVRSIKKTDLCPIYIFVQPPSLDV 129
           TS  +V+ V    R C+LDV    ++ ++   L PI IF++P  L++
Sbjct: 190 TSVASVKEVAEQGRHCILDVSGNAIKRLQVAGLYPIAIFIKPSRLNL 330
>11512
          Length = 1006

 Score = 83.6 bits (205), Expect = 5e-17,   Method: Compositional matrix adjust.
 Identities = 48/140 (34%), Positives = 72/140 (51%), Gaps = 9/140 (6%)
 Frame = -3

Query: 53   YYFVTREMMQRDIAAGDFIEHAEFSGNLYGTSKEAVRAVQAMNRICVLDVDLQGVRSIKK 112
            Y FV RE M  DI AG F+EH E+ G+LYGTS E+V+++     +CVL    Q +++++ 
Sbjct: 1004 YIFVAREKMDADIEAGKFVEHGEYKGHLYGTSAESVKSIVNAGCVCVLSPHYQAIKTLRT 825

Query: 113  TDLCPIYIFVQPPSLDVLEQ---RLRLRNTETEESLAKRLAAARTDMESSKE------PG 163
              L P  I ++PP LD+L+      R ++T  E +          DM  S          
Sbjct: 824  XQLKPFLIHIKPPELDILKSTRTEARAKSTFDEANARSFTDEEFEDMIKSTXRIDFTYGH 645

Query: 164  LFDLVIINDDLDKAYATLKQ 183
             FD+ I+N +L  A+  L Q
Sbjct: 644  FFDVEIVNGELLAAFEXLVQ 585
>37412
          Length = 757

 Score = 48.1 bits (113), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 40/155 (25%), Positives = 68/155 (43%), Gaps = 18/155 (11%)
 Frame = -1

Query: 58  REMMQRDIAAGDFIEHAEFSGNLYGTSKEAVRAVQAMNRICVLDVDLQGVRSIKKTDLCP 117
           R  M+ DI +G ++E+ +F+GNLYGT  + VR +    R       L   +S ++   CP
Sbjct: 739 RLTMESDIMSGRYLEYGDFNGNLYGTRLDTVRQIVDSGRCVCWTSTLPH*KSSRRPSSCP 560

Query: 118 IYIFVQPPSLDVLEQRLRLRNTETEESLAKRLAAARTD----------MESSKEP----- 162
                  P    L  +L    T+ ++ L    AAA +           +E+ KE      
Sbjct: 559 --TLCSSPR---LAWKLSKSCTKMDDGLH---AAAGSVVELK*NGGNFIETMKESQQIER 404

Query: 163 ---GLFDLVIINDDLDKAYATLKQALSEEIKKAQG 194
                FD +I+ND  +  Y  L+++L+  ++   G
Sbjct: 403 VYASYFDDIIVNDSFEDTYRQLRRSLTN*LQNNSG 299
>38795
          Length = 792

 Score = 29.6 bits (65), Expect = 0.93,   Method: Compositional matrix adjust.
 Identities = 13/16 (81%), Positives = 14/16 (87%)
 Frame = +1

Query: 7   VVLSGPSGAGKSTLLK 22
           V L GP+GAGKSTLLK
Sbjct: 724 VALVGPNGAGKSTLLK 771
>20270
          Length = 542

 Score = 28.1 bits (61), Expect = 2.6,   Method: Compositional matrix adjust.
 Identities = 15/35 (42%), Positives = 21/35 (60%)
 Frame = -3

Query: 5   RPVVLSGPSGAGKSTLLKKLFQEHSSIFGFSVSHT 39
           R ++L GP G GKS L K +  E ++   FSVS +
Sbjct: 378 RGILLYGPPGTGKSYLAKAVATEANNSTFFSVSSS 274
>15740
          Length = 545

 Score = 26.6 bits (57), Expect = 7.7,   Method: Compositional matrix adjust.
 Identities = 10/18 (55%), Positives = 15/18 (83%)
 Frame = +1

Query: 20 LLKKLFQEHSSIFGFSVS 37
          L+KKLF  HS++F F++S
Sbjct: 52 LIKKLFLVHSAVFSFNMS 105
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|118197277|ref|NP_032019.2| fibrillin 1 [Mus musculus]
         (2873 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

14371                                                                 117   6e-26
34993                                                                 112   3e-24
03773                                                                 107   6e-23
28816                                                                  83   2e-20
11992                                                                  96   2e-19
34726                                                                  85   4e-16
13514                                                                  80   1e-14
25748                                                                  77   1e-13
14599                                                                  74   6e-13
07364                                                                  70   1e-11
12576                                                                  50   7e-11
30893                                                                  61   6e-09
11667                                                                  60   1e-08
13401                                                                  57   7e-08
18708                                                                  57   1e-07
26257                                                                  54   8e-07
09271                                                                  54   8e-07
14158                                                                  50   1e-05
25877                                                                  49   4e-05
06474                                                                  44   0.001
09839                                                                  39   0.021
17529                                                                  39   0.031
32228                                                                  38   0.053
36274                                                                  37   0.11 
37574                                                                  37   0.13 
08033                                                                  37   0.15 
00070                                                                  36   0.19 
33353                                                                  34   0.74 
14910                                                                  34   0.88 
05519                                                                  33   1.5  
03995                                                                  33   1.6  
18717                                                                  32   4.1  
09979                                                                  32   5.0  
12472                                                                  32   5.2  
00974                                                                  31   5.9  
31203                                                                  31   6.2  
>14371
          Length = 627

 Score =  117 bits (294), Expect = 6e-26,   Method: Compositional matrix adjust.
 Identities = 81/201 (40%), Positives = 101/201 (50%), Gaps = 28/201 (13%)
 Frame = +3

Query: 2426 SYHC--ICKTGYTPDITGTACVDLNECNQAPKPCNFICKNTEGSYQCSCPKGYILQEDGR 2483
            SY C  +C  G+     G+ C D+NEC   P+ C   C+N  GSY+CSC +GY L ++GR
Sbjct: 3    SYQCSAVCGNGFRRSQDGSKCEDINECADTPEVCAQSCQNLIGSYRCSCTRGYRLGDNGR 182

Query: 2484 SCKDLDECATKQHNCQFLCVNTIGGFTCKCPPGFT-QHHTACIDNNECTSDINLCGSKGV 2542
             C D++EC      C   CVNT G + C CP G+      AC D NEC    + C S+  
Sbjct: 183  -CIDINECEQPSTKCSHDCVNTPGSYRCACPVGYRLTAGRACRDINECYERNHRCASEQE 359

Query: 2543 CQNTPGSFTCE--CQRGFSLDQSGASCEDVDECEGN-HR--------------------- 2578
            C N  GS+ C   C RGF    SG  C+DVDEC  N HR                     
Sbjct: 360  CINNEGSYQCVRLCPRGFVRTASG-ECQDVDECASNTHRCYNNQRCVNNDDINECRLRSD 536

Query: 2579 -CQHGCQNIIGGYRCSCPQGY 2598
             CQH C N  G Y+CSCP+GY
Sbjct: 537  ICQHNCSNTRGSYQCSCPKGY 599

 Score =  109 bits (272), Expect = 2e-23,   Method: Compositional matrix adjust.
 Identities = 79/213 (37%), Positives = 106/213 (49%), Gaps = 28/213 (13%)
 Frame = +3

Query: 1220 SYECS--CQPGFALMPDQRSCTDIDECEDNPNICDGGQCTNIPGEYRCLCYDGFMASEDM 1277
            SY+CS  C  GF    D   C DI+EC D P +C    C N+ G YRC C  G+   ++ 
Sbjct: 3    SYQCSAVCGNGFRRSQDGSKCEDINECADTPEVC-AQSCQNLIGSYRCSCTRGYRLGDNG 179

Query: 1278 KTCVDVNECDLNPNICLSGTCENTKGSFICHCDMGYSGKKGKTGCTDINECEIGAHNCGR 1337
            + C+D+NEC+  P+   S  C NT GS+ C C +GY    G+  C DINEC    H C  
Sbjct: 180  R-CIDINECE-QPSTKCSHDCVNTPGSYRCACPVGYRLTAGR-ACRDINECYERNHRCAS 350

Query: 1338 HAVCTNTAGSFKCS--CSPGWIGDGI-KCTDLDECSNGTHMCS----------------- 1377
               C N  GS++C   C  G++     +C D+DEC++ TH C                  
Sbjct: 351  EQECINNEGSYQCVRLCPRGFVRTASGECQDVDECASNTHRCYNNQRCVNNDDINECRLR 530

Query: 1378 ----QHADCKNTMGSYRCLCKDGY--TGDGFTC 1404
                QH +C NT GSY+C C  GY    DG++C
Sbjct: 531  SDICQH-NCSNTRGSYQCSCPKGYRLAADGYSC 626

 Score =  105 bits (262), Expect = 3e-22,   Method: Compositional matrix adjust.
 Identities = 74/206 (35%), Positives = 105/206 (50%), Gaps = 27/206 (13%)
 Frame = +3

Query: 1877 LCHTGFKTNVDQTMCLDINECER--DACGNGTCRNTIGSFNCRCNHGFILSHNNDCIDVD 1934
            +C  GF+ + D + C DINEC    + C   +C+N IGS+ C C  G+ L  N  CID++
Sbjct: 21   VCGNGFRRSQDGSKCEDINECADTPEVCAQ-SCQNLIGSYRCSCTRGYRLGDNGRCIDIN 197

Query: 1935 ECATGNGNLCRNGQCVNTVGSFQCRCNEGYEVAPDGRTCVDINECVLDPGKCAP-GTCQN 1993
            EC   +     +  CVNT GS++C C  GY +   GR C DINEC     +CA    C N
Sbjct: 198  ECEQPSTKC--SHDCVNTPGSYRCACPVGYRLTA-GRACRDINECYERNHRCASEQECIN 368

Query: 1994 LDGSYRCI--CPPGY-SLQNDKCEDIDECVEEPEICA---------------------LG 2029
             +GSY+C+  CP G+    + +C+D+DEC      C                        
Sbjct: 369  NEGSYQCVRLCPRGFVRTASGECQDVDECASNTHRCYNNQRCVNNDDINECRLRSDICQH 548

Query: 2030 TCSNTEGSFKCLCPEGFSLSSTGRRC 2055
             CSNT GS++C CP+G+ L++ G  C
Sbjct: 549  NCSNTRGSYQCSCPKGYRLAADGYSC 626

 Score =  102 bits (255), Expect = 2e-21,   Method: Compositional matrix adjust.
 Identities = 78/227 (34%), Positives = 110/227 (48%), Gaps = 5/227 (2%)
 Frame = +3

Query: 1266 LCYDGFMASEDMKTCVDVNECDLNPNICLSGTCENTKGSFICHCDMGYS-GKKGKTGCTD 1324
            +C +GF  S+D   C D+NEC   P +C + +C+N  GS+ C C  GY  G  G+  C D
Sbjct: 21   VCGNGFRRSQDGSKCEDINECADTPEVC-AQSCQNLIGSYRCSCTRGYRLGDNGR--CID 191

Query: 1325 INECEIGAHNCGRHAVCTNTAGSFKCSCSPGW-IGDGIKCTDLDECSNGTHMCSQHADCK 1383
            INECE  +  C     C NT GS++C+C  G+ +  G  C D++EC    H C+   +C 
Sbjct: 192  INECEQPSTKCSHD--CVNTPGSYRCACPVGYRLTAGRACRDINECYERNHRCASEQECI 365

Query: 1384 NTMGSYRC--LCKDGYTGDGF-TCTDLDECSEXXXXXXXXXXXXAPGGYRCECDMGFVPS 1440
            N  GSY+C  LC  G+       C D+DEC              A   +RC  +   V +
Sbjct: 366  NNEGSYQCVRLCPRGFVRTASGECQDVDEC--------------ASNTHRCYNNQRCVNN 503

Query: 1441 ADGKACEDIDECSLPNICVFGTCHNLPGLFRCECEIGYELDRSGGNC 1487
                  +DI+EC L +      C N  G ++C C  GY L   G +C
Sbjct: 504  ------DDINECRLRSDICQHNCSNTRGSYQCSCPKGYRLAADGYSC 626

 Score =  101 bits (251), Expect = 4e-21,   Method: Compositional matrix adjust.
 Identities = 87/232 (37%), Positives = 111/232 (47%), Gaps = 22/232 (9%)
 Frame = +3

Query: 1955 SFQCR--CNEGYEVAPDGRTCVDINECVLDPGKCAPGTCQNLDGSYRCICPPGYSL-QND 2011
            S+QC   C  G+  + DG  C DINEC   P  CA  +CQNL GSYRC C  GY L  N 
Sbjct: 3    SYQCSAVCGNGFRRSQDGSKCEDINECADTPEVCAQ-SCQNLIGSYRCSCTRGYRLGDNG 179

Query: 2012 KCEDIDECVEEPEICALGTCSNTEGSFKCLCPEGFSLSSTGRRCQDLRMSYCYAKFEGGK 2071
            +C DI+EC E+P       C NT GS++C CP G+ L++ GR C+D+   Y         
Sbjct: 180  RCIDINEC-EQPSTKCSHDCVNTPGSYRCACPVGYRLTA-GRACRDINECY--------- 326

Query: 2072 CSSPKSRNH---SKQECCCALKGEGWGDPCELCPTEPDEAFRQICPFGSGIIVGPDDSAV 2128
                  RNH   S+QEC   +  EG      LCP       R      SG     D+ A 
Sbjct: 327  -----ERNHRCASEQEC---INNEGSYQCVRLCP-------RGFVRTASGECQDVDECAS 461

Query: 2129 ---------------DMDECK-EPDVCRHGQCINTDGSYRCECPFGYILEGN 2164
                           D++EC+   D+C+H  C NT GSY+C CP GY L  +
Sbjct: 462  NTHRCYNNQRCVNNDDINECRLRSDICQHN-CSNTRGSYQCSCPKGYRLAAD 614

 Score =  101 bits (251), Expect = 5e-21,   Method: Compositional matrix adjust.
 Identities = 84/209 (40%), Positives = 113/209 (54%), Gaps = 3/209 (1%)
 Frame = +3

Query: 1768 DIDECREIPGVCENGVCINMVGSFRCECPVGFFYNDKLLVCEDIDECQNGPVCQRNAECI 1827
            DI+EC + P VC    C N++GS+RC C  G+   D    C DI+EC+  P  + + +C+
Sbjct: 69   DINECADTPEVCAQS-CQNLIGSYRCSCTRGYRLGDNGR-CIDINECEQ-PSTKCSHDCV 239

Query: 1828 NTAGSYRCDCKPGYRLTSTGQCNDRNECQEIPNIC-SHGQCIDTVGSFYC--LCHTGFKT 1884
            NT GSYRC C  GYRLT+   C D NEC E  + C S  +CI+  GS+ C  LC  GF  
Sbjct: 240  NTPGSYRCACPVGYRLTAGRACRDINECYERNHRCASEQECINNEGSYQCVRLCPRGF-V 416

Query: 1885 NVDQTMCLDINECERDACGNGTCRNTIGSFNCRCNHGFILSHNNDCIDVDECATGNGNLC 1944
                  C D++EC   A     C N     N RC        NND  D++EC     ++C
Sbjct: 417  RTASGECQDVDEC---ASNTHRCYN-----NQRC-------VNND--DINECRL-RSDIC 542

Query: 1945 RNGQCVNTVGSFQCRCNEGYEVAPDGRTC 1973
            ++  C NT GS+QC C +GY +A DG +C
Sbjct: 543  QHN-CSNTRGSYQCSCPKGYRLAADGYSC 626

 Score = 99.0 bits (245), Expect = 2e-20,   Method: Compositional matrix adjust.
 Identities = 77/195 (39%), Positives = 98/195 (50%), Gaps = 7/195 (3%)
 Frame = +3

Query: 467 CIPTPGSYRCECNKGFQLDIRGECIDVDECEKNPCT--GGECINNQGSYTCHCRAGYQST 524
           C    GSYRC C +G++L   G CID++ECE+ P T    +C+N  GSY C C  GY+ T
Sbjct: 114 CQNLIGSYRCSCTRGYRLGDNGRCIDINECEQ-PSTKCSHDCVNTPGSYRCACPVGYRLT 290

Query: 525 LTRTECRDIDECLQ-NGRICNNGRCINTDGSFHCV--CNAGFHVTRDGKNCEDMDEC-SI 580
             R  CRDI+EC + N R  +   CIN +GS+ CV  C  GF  T  G+ C+D+DEC S 
Sbjct: 291 AGRA-CRDINECYERNHRCASEQECINNEGSYQCVRLCPRGFVRTASGE-CQDVDECASN 464

Query: 581 RNMCLNGM-CINEDGSFKCICKPGFQLASDGRYCKDINECETPGICMNGRCVNTDGSYRC 639
            + C N   C+N D                     DINEC          C NT GSY+C
Sbjct: 465 THRCYNNQRCVNND---------------------DINECRLRSDICQHNCSNTRGSYQC 581

Query: 640 ECFPGLAVGLDGRVC 654
            C  G  +  DG  C
Sbjct: 582 SCPKGYRLAADGYSC 626

 Score = 97.8 bits (242), Expect = 6e-20,   Method: Compositional matrix adjust.
 Identities = 74/213 (34%), Positives = 104/213 (48%), Gaps = 26/213 (12%)
 Frame = +3

Query: 1052 SFKCR--CDSGFALDSEERNCTDIDECRISPDLCGRGQCVNTPGDFECKCDEGYESGFMM 1109
            S++C   C +GF    +   C DI+EC  +P++C +  C N  G + C C  GY  G   
Sbjct: 3    SYQCSAVCGNGFRRSQDGSKCEDINECADTPEVCAQS-CQNLIGSYRCSCTRGYRLGDNG 179

Query: 1110 MKNCMDIDECQRDPLLCRGGICHNTEGSYRCECPPGHQLSPNISACIDINECELSANLCP 1169
               C+DI+EC++    C    C NT GSYRC CP G++L+    AC DINEC    + C 
Sbjct: 180  R--CIDINECEQPSTKC-SHDCVNTPGSYRCACPVGYRLTAG-RACRDINECYERNHRCA 347

Query: 1170 HGR-CVNLIGKYQCA--------------------CNPGYHPTHDRLFCV---DIDECSI 1205
              + C+N  G YQC                     C    H  ++   CV   DI+EC +
Sbjct: 348  SEQECINNEGSYQCVRLCPRGFVRTASGECQDVDECASNTHRCYNNQRCVNNDDINECRL 527

Query: 1206 MNGGCETFCTNSDGSYECSCQPGFALMPDQRSC 1238
             +  C+  C+N+ GSY+CSC  G+ L  D  SC
Sbjct: 528  RSDICQHNCSNTRGSYQCSCPKGYRLAADGYSC 626

 Score = 97.4 bits (241), Expect = 8e-20,   Method: Compositional matrix adjust.
 Identities = 73/189 (38%), Positives = 96/189 (50%), Gaps = 25/189 (13%)
 Frame = +3

Query: 2404 DIDECKVIHDVCRNGECVNDRGSYHCICKTGYTPDITGTACVDLNECNQAPKPCNFICKN 2463
            DI+EC    +VC    C N  GSY C C  GY     G  C+D+NEC Q    C+  C N
Sbjct: 69   DINECADTPEVCAQS-CQNLIGSYRCSCTRGYRLGDNGR-CIDINECEQPSTKCSHDCVN 242

Query: 2464 TEGSYQCSCPKGYILQEDGRSCKDLDECATKQHNC--QFLCVNTIGGFTCK--CPPGFTQ 2519
            T GSY+C+CP GY L   GR+C+D++EC  + H C  +  C+N  G + C   CP GF +
Sbjct: 243  TPGSYRCACPVGYRLTA-GRACRDINECYERNHRCASEQECINNEGSYQCVRLCPRGFVR 419

Query: 2520 HHTA-CIDNNECTS---------------DINLCGSKG-VCQ----NTPGSFTCECQRGF 2558
              +  C D +EC S               DIN C  +  +CQ    NT GS+ C C +G+
Sbjct: 420  TASGECQDVDECASNTHRCYNNQRCVNNDDINECRLRSDICQHNCSNTRGSYQCSCPKGY 599

Query: 2559 SLDQSGASC 2567
             L   G SC
Sbjct: 600  RLAADGYSC 626

 Score = 97.1 bits (240), Expect = 8e-20,   Method: Compositional matrix adjust.
 Identities = 78/217 (35%), Positives = 99/217 (45%), Gaps = 1/217 (0%)
 Frame = +3

Query: 1433 CDMGFVPSADGKACEDIDECS-LPNICVFGTCHNLPGLFRCECEIGYELDRSGGNCTDVN 1491
            C  GF  S DG  CEDI+EC+  P +C   +C NL G +RC C  GY L    G C D+N
Sbjct: 24   CGNGFRRSQDGSKCEDINECADTPEVCA-QSCQNLIGSYRCSCTRGYRLG-DNGRCIDIN 197

Query: 1492 ECLDPTTCISGNCVNTPGSYTCDCPPDFELNPTRVGCVDTRSGNCYLDIRPRGDNGDTAC 1551
            EC  P+T  S +CVNTPGSY C CP  + L   R  C D     CY   R      +  C
Sbjct: 198  ECEQPSTKCSHDCVNTPGSYRCACPVGYRLTAGRA-CRDI--NECYE--RNHRCASEQEC 362

Query: 1552 SNEIGVGVSKASCCCSLGKAWGTPCELCPSVNTSEYKILCPGGEGFRPNPITVILEDIDE 1611
             N  G       C     +     C+      ++ ++           N   V  +DI+E
Sbjct: 363  INNEGSYQCVRLCPRGFVRTASGECQDVDECASNTHRCY--------NNQRCVNNDDINE 518

Query: 1612 CQELPGLCQGGKCINTFGSFQCRCPTGYYLNEDTRVC 1648
            C+    +CQ   C NT GS+QC CP GY L  D   C
Sbjct: 519  CRLRSDICQ-HNCSNTRGSYQCSCPKGYRLAADGYSC 626

 Score = 95.1 bits (235), Expect = 3e-19,   Method: Compositional matrix adjust.
 Identities = 76/204 (37%), Positives = 95/204 (46%), Gaps = 29/204 (14%)
 Frame = +3

Query: 2513 CPPGF--TQHHTACIDNNECTSDINLCGSKGVCQNTPGSFTCECQRGFSLDQSGASCEDV 2570
            C  GF  +Q  + C D NEC     +C     CQN  GS+ C C RG+ L  +G  C D+
Sbjct: 24   CGNGFRRSQDGSKCEDINECADTPEVCAQS--CQNLIGSYRCSCTRGYRLGDNG-RCIDI 194

Query: 2571 DECEG-NHRCQHGCQNIIGGYRCSCPQGYLQHYQWNQCVDENECLSA-HVCGG-ASCHNT 2627
            +ECE  + +C H C N  G YRC+CP GY +      C D NEC    H C     C N 
Sbjct: 195  NECEQPSTKCSHDCVNTPGSYRCACPVGY-RLTAGRACRDINECYERNHRCASEQECINN 371

Query: 2628 LGSYKC--MCPTGFQYEQFSGGCQDINECGSSQAPC----------------------SY 2663
             GSY+C  +CP GF     SG CQD++EC S+   C                       +
Sbjct: 372  EGSYQCVRLCPRGF-VRTASGECQDVDECASNTHRCYNNQRCVNNDDINECRLRSDICQH 548

Query: 2664 GCSNTEGGYLCGCPPGYFRIGQGH 2687
             CSNT G Y C CP GY     G+
Sbjct: 549  NCSNTRGSYQCSCPKGYRLAADGY 620

 Score = 90.9 bits (224), Expect = 6e-18,   Method: Compositional matrix adjust.
 Identities = 69/193 (35%), Positives = 88/193 (45%), Gaps = 24/193 (12%)
 Frame = +3

Query: 1029 KDINECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQC 1088
            +DINEC   P +C    C+N IGS++C C  G+ L    R C DI+EC      C    C
Sbjct: 66   EDINECADTPEVCAQS-CQNLIGSYRCSCTRGYRLGDNGR-CIDINECEQPSTKCSH-DC 236

Query: 1089 VNTPGDFECKCDEGYESGFMMMKNCMDIDEC-QRDPLLCRGGICHNTEGSYRC------- 1140
            VNTPG + C C  GY       + C DI+EC +R+        C N EGSY+C       
Sbjct: 237  VNTPGSYRCACPVGYR--LTAGRACRDINECYERNHRCASEQECINNEGSYQCVRLCPRG 410

Query: 1141 -------ECPPGHQLSPNISACI---------DINECELSANLCPHGRCVNLIGKYQCAC 1184
                   EC    + + N   C          DINEC L +++C H  C N  G YQC+C
Sbjct: 411  FVRTASGECQDVDECASNTHRCYNNQRCVNNDDINECRLRSDICQHN-CSNTRGSYQCSC 587

Query: 1185 NPGYHPTHDRLFC 1197
              GY    D   C
Sbjct: 588  PKGYRLAADGYSC 626

 Score = 89.7 bits (221), Expect = 1e-17,   Method: Compositional matrix adjust.
 Identities = 88/264 (33%), Positives = 112/264 (42%), Gaps = 7/264 (2%)
 Frame = +3

Query: 2229 SYECK--CPVGYVLREDRRMCKDEDECAEGKHDCTEKQMECKNLIGTYMCICGPGYQRRP 2286
            SY+C   C  G+   +D   C+D +ECA+    C +    C+NLIG+Y C C  GY R  
Sbjct: 3    SYQCSAVCGNGFRRSQDGSKCEDINECADTPEVCAQS---CQNLIGSYRCSCTRGY-RLG 170

Query: 2287 DGEGCIDENECQTKPGICENGRCLNTLGSYTCECNDGFTASPTQDECLDNREGYCFSEVL 2346
            D   CID NEC+     C +  C+NT GSY C C  G+  +  +  C D  E Y      
Sbjct: 171  DNGRCIDINECEQPSTKCSHD-CVNTPGSYRCACPVGYRLTAGR-ACRDINECY------ 326

Query: 2347 QNMCQIGSSNRNPVTKSECCCDGGRGWGPHCEICPFEGTVAYKKLCPHGRGFMTNGA--- 2403
                     N    ++ EC                 EG+    +LCP  RGF+   +   
Sbjct: 327  -------ERNHRCASEQECI--------------NNEGSYQCVRLCP--RGFVRTASGEC 437

Query: 2404 -DIDECKV-IHDVCRNGECVNDRGSYHCICKTGYTPDITGTACVDLNECNQAPKPCNFIC 2461
             D+DEC    H    N  CVN+                      D+NEC      C   C
Sbjct: 438  QDVDECASNTHRCYNNQRCVNND---------------------DINECRLRSDICQHNC 554

Query: 2462 KNTEGSYQCSCPKGYILQEDGRSC 2485
             NT GSYQCSCPKGY L  DG SC
Sbjct: 555  SNTRGSYQCSCPKGYRLAADGYSC 626

 Score = 88.2 bits (217), Expect = 4e-17,   Method: Compositional matrix adjust.
 Identities = 77/240 (32%), Positives = 102/240 (42%), Gaps = 28/240 (11%)
 Frame = +3

Query: 554 SFHC--VCNAGFHVTRDGKNCEDMDECSIRNMCLNGMCINEDGSFKCICKPGFQLASDGR 611
           S+ C  VC  GF  ++DG  CED++EC+         C N  GS++C C  G++L  +GR
Sbjct: 3   SYQCSAVCGNGFRRSQDGSKCEDINECADTPEVCAQSCQNLIGSYRCSCTRGYRLGDNGR 182

Query: 612 YCKDINECETPGICMNGRCVNTDGSYRCECFPGLAVGLDGRVCVDTHMRSTCYGGYRRGQ 671
            C DINECE P    +  CVNT GSYRC C  G  +   GR C D +            +
Sbjct: 183 -CIDINECEQPSTKCSHDCVNTPGSYRCACPVGYRLTA-GRACRDIN------------E 320

Query: 672 CVKPLFGAVTKSECCCASTEYAFGEPCQPCPAQNSAEYQ--ALCSSGPGMTSAGT----- 724
           C +      ++ EC                   N   YQ   LC  G   T++G      
Sbjct: 321 CYERNHRCASEQEC-----------------INNEGSYQCVRLCPRGFVRTASGECQDVD 449

Query: 725 -------------------DINECALDPDICPNGICENLRGTYKCICNSGYEVDITGKNC 765
                              DINEC L  DIC +  C N RG+Y+C C  GY +   G +C
Sbjct: 450 ECASNTHRCYNNQRCVNNDDINECRLRSDICQHN-CSNTRGSYQCSCPKGYRLAADGYSC 626

 Score = 86.7 bits (213), Expect = 1e-16,   Method: Compositional matrix adjust.
 Identities = 78/248 (31%), Positives = 112/248 (45%), Gaps = 6/248 (2%)
 Frame = +3

Query: 711 ALCSSGPGMTSAGT---DINECALDPDICPNGICENLRGTYKCICNSGYEVDITGKNCVD 767
           A+C +G   +  G+   DINECA  P++C    C+NL G+Y+C C  GY +   G+ C+D
Sbjct: 18  AVCGNGFRRSQDGSKCEDINECADTPEVCAQS-CQNLIGSYRCSCTRGYRLGDNGR-CID 191

Query: 768 INECVLNSLLCDNGQCRNTPGSFVCTCPKGFVYKPDLKTCEDIDEC--ESSPCIN-GVCK 824
           INEC   S  C +  C NTPGS+ C CP G+      + C DI+EC   +  C +   C 
Sbjct: 192 INECEQPSTKCSH-DCVNTPGSYRCACPVGYRLTAG-RACRDINECYERNHRCASEQECI 365

Query: 825 NSPGSFICECSPESTLDPTKTICIETIKGTCWQTVIDGRCEININGATLKSECCSSLGAA 884
           N+ GS+ C       L P   +   T  G C                    EC S+    
Sbjct: 366 NNEGSYQC-----VRLCPRGFV--RTASGECQDV----------------DECASNTHRC 476

Query: 885 WGSPCTICQLDPICGKGFSRIKGTQCEDINECEVFPGVCKNGLCVNSRGSFKCECPNGMT 944
           + +                  +    +DINEC +   +C++  C N+RGS++C CP G  
Sbjct: 477 YNNQ-----------------RCVNNDDINECRLRSDICQHN-CSNTRGSYQCSCPKGYR 602

Query: 945 LDATGRIC 952
           L A G  C
Sbjct: 603 LAADGYSC 626

 Score = 86.3 bits (212), Expect = 2e-16,   Method: Compositional matrix adjust.
 Identities = 57/140 (40%), Positives = 71/140 (50%), Gaps = 5/140 (3%)
 Frame = +3

Query: 2554 CQRGFSLDQSGASCEDVDECEGN-HRCQHGCQNIIGGYRCSCPQGYLQHYQWNQCVDENE 2612
            C  GF   Q G+ CED++EC      C   CQN+IG YRCSC +GY +     +C+D NE
Sbjct: 24   CGNGFRRSQDGSKCEDINECADTPEVCAQSCQNLIGSYRCSCTRGY-RLGDNGRCIDINE 200

Query: 2613 CLSAHVCGGASCHNTLGSYKCMCPTGFQYEQFSGGCQDINECGSSQAPCS--YGCSNTEG 2670
            C          C NT GSY+C CP G++       C+DINEC      C+    C N EG
Sbjct: 201  CEQPSTKCSHDCVNTPGSYRCACPVGYRL-TAGRACRDINECYERNHRCASEQECINNEG 377

Query: 2671 GYLCG--CPPGYFRIGQGHC 2688
             Y C   CP G+ R   G C
Sbjct: 378  SYQCVRLCPRGFVRTASGEC 437

 Score = 84.0 bits (206), Expect = 9e-16,   Method: Compositional matrix adjust.
 Identities = 80/238 (33%), Positives = 99/238 (41%), Gaps = 25/238 (10%)
 Frame = +3

Query: 2116 GSGIIVGPDDSAV-DMDECKE-PDVCRHGQCINTDGSYRCECPFGYILEGNECVDTDECS 2173
            G+G     D S   D++EC + P+VC    C N  GSYRC C  GY L  N         
Sbjct: 27   GNGFRRSQDGSKCEDINECADTPEVCAQS-CQNLIGSYRCSCTRGYRLGDN--------- 176

Query: 2174 VGNPCGNGTCKNVIXXXXXXXXXXXXXXXMMTCEDINECAQNPLLCAFRCVNTYGSYECK 2233
                                            C DINEC Q    C+  CVNT GSY C 
Sbjct: 177  ------------------------------GRCIDINECEQPSTKCSHDCVNTPGSYRCA 266

Query: 2234 CPVGYVLREDRRMCKDEDECAEGKHDCTEKQMECKNLIGTYMCI--CGPGYQRRPDGE-- 2289
            CPVGY L    R C+D +EC E  H C  +Q EC N  G+Y C+  C  G+ R   GE  
Sbjct: 267  CPVGYRLTAG-RACRDINECYERNHRCASEQ-ECINNEGSYQCVRLCPRGFVRTASGECQ 440

Query: 2290 ----------------GCI---DENECQTKPGICENGRCLNTLGSYTCECNDGFTASP 2328
                             C+   D NEC+ +  IC++  C NT GSY C C  G+  + 
Sbjct: 441  DVDECASNTHRCYNNQRCVNNDDINECRLRSDICQHN-CSNTRGSYQCSCPKGYRLAA 611

 Score = 74.7 bits (182), Expect = 5e-13,   Method: Compositional matrix adjust.
 Identities = 67/210 (31%), Positives = 92/210 (43%), Gaps = 4/210 (1%)
 Frame = +3

Query: 1594 GEGFRPNPITVILEDIDECQELPGLCQGGKCINTFGSFQCRCPTGYYLNEDTRVCDDVNE 1653
            G GFR +      EDI+EC + P +C    C N  GS++C C  GY L ++ R C D+NE
Sbjct: 27   GNGFRRSQDGSKCEDINECADTPEVC-AQSCQNLIGSYRCSCTRGYRLGDNGR-CIDINE 200

Query: 1654 CETPGICGPGTCYNTVGNYTCICPPDYMQVNGGNNCMDMRRSLCYRNYYADNQTC--DGE 1711
            CE P       C NT G+Y C CP  Y ++  G  C D+         Y  N  C  + E
Sbjct: 201  CEQPSTKCSHDCVNTPGSYRCACPVGY-RLTAGRACRDINEC------YERNHRCASEQE 359

Query: 1712 LLFNMTKKMCC--CSYNIGRAWNKPCEQCPIPSTDEFATLCGSQRPGFVIDIYTGLPVDI 1769
             + N     C   C     R  +  C+       DE    C S       +       DI
Sbjct: 360  CINNEGSYQCVRLCPRGFVRTASGECQ-----DVDE----CASNTHRCYNNQRCVNNDDI 512

Query: 1770 DECREIPGVCENGVCINMVGSFRCECPVGF 1799
            +ECR    +C++  C N  GS++C CP G+
Sbjct: 513  NECRLRSDICQHN-CSNTRGSYQCSCPKGY 599

 Score = 66.6 bits (161), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 51/153 (33%), Positives = 72/153 (47%), Gaps = 25/153 (16%)
 Frame = +3

Query: 1764 GLPVDIDECREIPGVCENGVCINMVGSFRCECPVGFFYNDKLLVCEDIDEC-QNGPVCQR 1822
            G  +DI+EC +    C +  C+N  GS+RC CPVG+        C DI+EC +    C  
Sbjct: 177  GRCIDINECEQPSTKCSHD-CVNTPGSYRCACPVGYRLT-AGRACRDINECYERNHRCAS 350

Query: 1823 NAECINTAGSYRCD--CKPGYRLTSTGQC----------------------NDRNECQEI 1858
              ECIN  GSY+C   C  G+  T++G+C                      +D NEC+  
Sbjct: 351  EQECINNEGSYQCVRLCPRGFVRTASGECQDVDECASNTHRCYNNQRCVNNDDINECRLR 530

Query: 1859 PNICSHGQCIDTVGSFYCLCHTGFKTNVDQTMC 1891
             +IC H  C +T GS+ C C  G++   D   C
Sbjct: 531  SDICQHN-CSNTRGSYQCSCPKGYRLAADGYSC 626

 Score = 65.5 bits (158), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 69/214 (32%), Positives = 92/214 (42%), Gaps = 36/214 (16%)
 Frame = +3

Query: 893  QLDPICGKGFSRIK-GTQCEDINECEVFPGVCKNGLCVNSRGSFKCECPNGMTLDATGRI 951
            Q   +CG GF R + G++CEDINEC   P VC    C N  GS++C C  G  L   GR 
Sbjct: 9    QCSAVCGNGFRRSQDGSKCEDINECADTPEVCAQS-CQNLIGSYRCSCTRGYRLGDNGR- 182

Query: 952  CLDI-RLETCFLKYDDEECTLPIAGRHRMDACCCSVG----AAWGTEECEECPLRNSREY 1006
            C+DI   E    K   +    P + R     C C VG    A     +  EC  RN R  
Sbjct: 183  CIDINECEQPSTKCSHDCVNTPGSYR-----CACPVGYRLTAGRACRDINECYERNHRCA 347

Query: 1007 EE--------------LCPRG----PGFATKDI----TNGKPFFK--------DINECKM 1036
             E              LCPRG         +D+    +N    +         DINEC++
Sbjct: 348  SEQECINNEGSYQCVRLCPRGFVRTASGECQDVDECASNTHRCYNNQRCVNNDDINECRL 527

Query: 1037 IPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNC 1070
               +C H  C NT GS++C C  G+ L ++  +C
Sbjct: 528  RSDICQH-NCSNTRGSYQCSCPKGYRLAADGYSC 626

 Score = 54.3 bits (129), Expect = 6e-07,   Method: Compositional matrix adjust.
 Identities = 62/229 (27%), Positives = 97/229 (42%), Gaps = 11/229 (4%)
 Frame = +3

Query: 1630 SFQCR--CPTGYYLNEDTRVCDDVNEC-ETPGICGPGTCYNTVGNYTCICPPDYMQVNGG 1686
            S+QC   C  G+  ++D   C+D+NEC +TP +C   +C N +G+Y C C   Y   + G
Sbjct: 3    SYQCSAVCGNGFRRSQDGSKCEDINECADTPEVCAQ-SCQNLIGSYRCSCTRGYRLGDNG 179

Query: 1687 NNCMDMRR-----SLCYRN--YYADNQTCDGELLFNMTKKMCCCSYNIGRAWNKPCEQCP 1739
              C+D+       + C  +      +  C   + + +T    C   N     N  C    
Sbjct: 180  R-CIDINECEQPSTKCSHDCVNTPGSYRCACPVGYRLTAGRACRDINECYERNHRCASEQ 356

Query: 1740 IPSTDEFATLCGSQRPGFVIDIYTGLPVDIDECREIPGVCENGVCINMVGSFRCECPVGF 1799
                +E +  C    P   +   +G   D+DEC                 + RC      
Sbjct: 357  ECINNEGSYQCVRLCPRGFVRTASGECQDVDEC--------------ASNTHRC------ 476

Query: 1800 FYNDKLLVCEDIDECQ-NGPVCQRNAECINTAGSYRCDCKPGYRLTSTG 1847
            + N + +  +DI+EC+    +CQ N  C NT GSY+C C  GYRL + G
Sbjct: 477  YNNQRCVNNDDINECRLRSDICQHN--CSNTRGSYQCSCPKGYRLAADG 617

 Score = 54.3 bits (129), Expect = 6e-07,   Method: Compositional matrix adjust.
 Identities = 67/241 (27%), Positives = 83/241 (34%), Gaps = 25/241 (10%)
 Frame = +3

Query: 1474 CEIGYELDRSGGNCTDVNECLDPTTCISGNCVNTPGSYTCDCPPDFELNPTRVGCVDTRS 1533
            C  G+   + G  C D+NEC D     + +C N  GSY C C   + L            
Sbjct: 24   CGNGFRRSQDGSKCEDINECADTPEVCAQSCQNLIGSYRCSCTRGYRL------------ 167

Query: 1534 GNCYLDIRPRGDNGDTACSNEIGVGVSKASCCCSLGKAWGTPCELCPSVNT-SEYKILCP 1592
                      GDNG     NE     +K S  C               VNT   Y+  CP
Sbjct: 168  ----------GDNGRCIDINECEQPSTKCSHDC---------------VNTPGSYRCACP 272

Query: 1593 GGEGFRPNPITVILEDIDECQELPGLCQGGK-CINTFGSFQC--RCPTGY---------- 1639
             G             DI+EC E    C   + CIN  GS+QC   CP G+          
Sbjct: 273  VGYRL---TAGRACRDINECYERNHRCASEQECINNEGSYQCVRLCPRGFVRTASGECQD 443

Query: 1640 -----------YLNEDTRVCDDVNECETPGICGPGTCYNTVGNYTCICPPDYMQVNGGNN 1688
                       Y N+     DD+NEC          C NT G+Y C CP  Y     G +
Sbjct: 444  VDECASNTHRCYNNQRCVNNDDINECRLRSDICQHNCSNTRGSYQCSCPKGYRLAADGYS 623

Query: 1689 C 1689
            C
Sbjct: 624  C 626

 Score = 45.1 bits (105), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 34/110 (30%), Positives = 48/110 (43%), Gaps = 24/110 (21%)
 Frame = +3

Query: 243 ACQDVDECQAIPGMCQG-GNCINTVGSFECK--CPAGHKFNEVSQKCEDIDECSTIPGVC 299
           AC+D++EC      C     CIN  GS++C   CP G      S +C+D+DEC++    C
Sbjct: 300 ACRDINECYERNHRCASEQECINNEGSYQCVRLCPRGF-VRTASGECQDVDECASNTHRC 476

Query: 300 DGGE---------------------CTNTVSSYFCKCPPGFYTSPDGTRC 328
              +                     C+NT  SY C CP G+  + DG  C
Sbjct: 477 YNNQRCVNNDDINECRLRSDICQHNCSNTRGSYQCSCPKGYRLAADGYSC 626

 Score = 44.3 bits (103), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 24/62 (38%), Positives = 31/62 (50%), Gaps = 2/62 (3%)
 Frame = +3

Query: 2630 SYKC--MCPTGFQYEQFSGGCQDINECGSSQAPCSYGCSNTEGGYLCGCPPGYFRIGQGH 2687
            SY+C  +C  GF+  Q    C+DINEC  +   C+  C N  G Y C C  GY     G 
Sbjct: 3    SYQCSAVCGNGFRRSQDGSKCEDINECADTPEVCAQSCQNLIGSYRCSCTRGYRLGDNGR 182

Query: 2688 CV 2689
            C+
Sbjct: 183  CI 188
>34993
          Length = 626

 Score =  112 bits (279), Expect = 3e-24,   Method: Compositional matrix adjust.
 Identities = 76/195 (38%), Positives = 110/195 (56%), Gaps = 10/195 (5%)
 Frame = -2

Query: 470 TPGSYRCECNKGFQL--DIRGECIDVDECEKNPCTGG---ECINNQGSYTCHCRAGYQST 524
           T GSYRC C+ GF+L  D++  C+DVDEC  +   GG   +C+N  G + C C  G +  
Sbjct: 619 TAGSYRCRCSMGFELAEDMK-SCLDVDECVSH--NGGCQHKCVNTYGGFNCECPKGQRLH 449

Query: 525 LTRTECRDIDEC-LQNG---RICNNGRCINTDGSFHCVCNAGFHVTRDGKNCEDMDECSI 580
           +    C  +  C + NG    +C +G     +G FHC C  G+ + +DGK+C++ + C  
Sbjct: 448 VDARTCIAVSGCSVXNGGCEHVCTDG----YNGHFHCRCRPGYTLAQDGKSCQEDNPCQH 281

Query: 581 RNMCLNGMCINEDGSFKCICKPGFQLASDGRYCKDINEC-ETPGICMNGRCVNTDGSYRC 639
            N      C+++ G   C C  G++LA+DGR CKDI+EC +  G C+  RCVNT GS+ C
Sbjct: 280 SNGGCQHTCVSDRGRAVCRCFQGYELAADGRSCKDIDECAKRNGDCLQ-RCVNTQGSFTC 104

Query: 640 ECFPGLAVGLDGRVC 654
            C  G  +G DGR C
Sbjct: 103 TCTQGYQLGNDGRSC 59

 Score =  110 bits (274), Expect = 1e-23,   Method: Compositional matrix adjust.
 Identities = 67/191 (35%), Positives = 91/191 (47%)
 Frame = -2

Query: 1090 NTPGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRGGICHNTEGSYRCECPPGHQLS 1149
            NT G + C+C  G+E     MK+C+D+DEC      C+   C NT G + CECP G +L 
Sbjct: 622  NTAGSYRCRCSMGFELA-EDMKSCLDVDECVSHNGGCQH-KCVNTYGGFNCECPKGQRLH 449

Query: 1150 PNISACIDINECELSANLCPHGRCVNLIGKYQCACNPGYHPTHDRLFCVDIDECSIMNGG 1209
             +   CI ++ C +    C H       G + C C PGY    D   C + + C   NGG
Sbjct: 448  VDARTCIAVSGCSVXNGGCEHVCTDGYNGHFHCRCRPGYTLAQDGKSCQEDNPCQHSNGG 269

Query: 1210 CETFCTNSDGSYECSCQPGFALMPDQRSCTDIDECEDNPNICDGGQCTNIPGEYRCLCYD 1269
            C+  C +  G   C C  G+ L  D RSC DIDEC      C   +C N  G + C C  
Sbjct: 268  CQHTCVSDRGRAVCRCFQGYELAADGRSCKDIDECAKRNGDCL-QRCVNTQGSFTCTCTQ 92

Query: 1270 GFMASEDMKTC 1280
            G+    D ++C
Sbjct: 91   GYQLGNDGRSC 59

 Score =  109 bits (272), Expect = 2e-23,   Method: Compositional matrix adjust.
 Identities = 69/191 (36%), Positives = 100/191 (52%)
 Frame = -2

Query: 1048 NTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQCVNTPGDFECKCDEGYESGF 1107
            NT GS++CRC  GF L  + ++C D+DEC +S +   + +CVNT G F C+C +G +   
Sbjct: 622  NTAGSYRCRCSMGFELAEDMKSCLDVDEC-VSHNGGCQHKCVNTYGGFNCECPKG-QRLH 449

Query: 1108 MMMKNCMDIDECQRDPLLCRGGICHNTEGSYRCECPPGHQLSPNISACIDINECELSANL 1167
            +  + C+ +  C      C         G + C C PG+ L+ +  +C + N C+ S   
Sbjct: 448  VDARTCIAVSGCSVXNGGCEHVCTDGYNGHFHCRCRPGYTLAQDGKSCQEDNPCQHSNGG 269

Query: 1168 CPHGRCVNLIGKYQCACNPGYHPTHDRLFCVDIDECSIMNGGCETFCTNSDGSYECSCQP 1227
            C H  CV+  G+  C C  GY    D   C DIDEC+  NG C   C N+ GS+ C+C  
Sbjct: 268  CQH-TCVSDRGRAVCRCFQGYELAADGRSCKDIDECAKRNGDCLQRCVNTQGSFTCTCTQ 92

Query: 1228 GFALMPDQRSC 1238
            G+ L  D RSC
Sbjct: 91   GYQLGNDGRSC 59

 Score =  105 bits (263), Expect = 2e-22,   Method: Compositional matrix adjust.
 Identities = 73/183 (39%), Positives = 97/183 (53%), Gaps = 4/183 (2%)
 Frame = -2

Query: 2462 KNTEGSYQCSCPKGYILQEDGRSCKDLDECATKQHNCQFLCVNTIGGFTCKCPPGFTQHH 2521
            +NT GSY+C C  G+ L ED +SC D+DEC +    CQ  CVNT GGF C+CP G   H 
Sbjct: 625  ENTAGSYRCRCSMGFELAEDMKSCLDVDECVSHNGGCQHKCVNTYGGFNCECPKGQRLHV 446

Query: 2522 TA--CIDNNECTSDINLCGSKGVCQN-TPGSFTCECQRGFSLDQSGASCEDVDECE-GNH 2577
             A  CI  + C+  +   G + VC +   G F C C+ G++L Q G SC++ + C+  N 
Sbjct: 445  DARTCIAVSGCS--VXNGGCEHVCTDGYNGHFHCRCRPGYTLAQDGKSCQEDNPCQHSNG 272

Query: 2578 RCQHGCQNIIGGYRCSCPQGYLQHYQWNQCVDENECLSAHVCGGASCHNTLGSYKCMCPT 2637
             CQH C +  G   C C QGY        C D +EC   +      C NT GS+ C C  
Sbjct: 271  GCQHTCVSDRGRAVCRCFQGYELAADGRSCKDIDECAKRNGDCLQRCVNTQGSFTCTCTQ 92

Query: 2638 GFQ 2640
            G+Q
Sbjct: 91   GYQ 83

 Score =  105 bits (262), Expect = 3e-22,   Method: Compositional matrix adjust.
 Identities = 77/194 (39%), Positives = 98/194 (50%), Gaps = 7/194 (3%)
 Frame = -2

Query: 1869 DTVGSFYCLCHTGFKTNVDQTMCLDINECERDACG-NGTCRNTIGSFNCRCNHGFILSHN 1927
            +T GS+ C C  GF+   D   CLD++EC     G    C NT G FNC C  G  L  +
Sbjct: 622  NTAGSYRCRCSMGFELAEDMKSCLDVDECVSHNGGCQHKCVNTYGGFNCECPKGQRLHVD 443

Query: 1928 -NDCIDVDECATGNG---NLCRNGQCVNTVGSFQCRCNEGYEVAPDGRTCVDINECVLDP 1983
               CI V  C+  NG   ++C +G      G F CRC  GY +A DG++C + N C    
Sbjct: 442  ARTCIAVSGCSVXNGGCEHVCTDG----YNGHFHCRCRPGYTLAQDGKSCQEDNPCQHSN 275

Query: 1984 GKCAPGTCQNLDGSYRCICPPGYSLQND--KCEDIDECVEEPEICALGTCSNTEGSFKCL 2041
            G C   TC +  G   C C  GY L  D   C+DIDEC +    C L  C NT+GSF C 
Sbjct: 274  GGCQH-TCVSDRGRAVCRCFQGYELAADGRSCKDIDECAKRNGDC-LQRCVNTQGSFTCT 101

Query: 2042 CPEGFSLSSTGRRC 2055
            C +G+ L + GR C
Sbjct: 100  CTQGYQLGNDGRSC 59

 Score =  103 bits (256), Expect = 1e-21,   Method: Compositional matrix adjust.
 Identities = 74/191 (38%), Positives = 100/191 (52%), Gaps = 7/191 (3%)
 Frame = -2

Query: 1828 NTAGSYRCDCKPGYRLTS-TGQCNDRNECQEIPNICSHGQCIDTVGSFYCLCHTGFKTNV 1886
            NTAGSYRC C  G+ L      C D +EC      C H +C++T G F C C  G + +V
Sbjct: 622  NTAGSYRCRCSMGFELAEDMKSCLDVDECVSHNGGCQH-KCVNTYGGFNCECPKGQRLHV 446

Query: 1887 DQTMCLDINECERDACGNGTCRNTI-----GSFNCRCNHGFILSHN-NDCIDVDECATGN 1940
            D   C+ ++ C   +  NG C +       G F+CRC  G+ L+ +   C + + C   N
Sbjct: 445  DARTCIAVSGC---SVXNGGCEHVCTDGYNGHFHCRCRPGYTLAQDGKSCQEDNPCQHSN 275

Query: 1941 GNLCRNGQCVNTVGSFQCRCNEGYEVAPDGRTCVDINECVLDPGKCAPGTCQNLDGSYRC 2000
            G  C++  CV+  G   CRC +GYE+A DGR+C DI+EC    G C    C N  GS+ C
Sbjct: 274  GG-CQH-TCVSDRGRAVCRCFQGYELAADGRSCKDIDECAKRNGDCLQ-RCVNTQGSFTC 104

Query: 2001 ICPPGYSLQND 2011
             C  GY L ND
Sbjct: 103  TCTQGYQLGND 71

 Score = 98.2 bits (243), Expect = 4e-20,   Method: Compositional matrix adjust.
 Identities = 60/182 (32%), Positives = 87/182 (47%)
 Frame = -2

Query: 1175 NLIGKYQCACNPGYHPTHDRLFCVDIDECSIMNGGCETFCTNSDGSYECSCQPGFALMPD 1234
            N  G Y+C C+ G+    D   C+D+DEC   NGGC+  C N+ G + C C  G  L  D
Sbjct: 622  NTAGSYRCRCSMGFELAEDMKSCLDVDECVSHNGGCQHKCVNTYGGFNCECPKGQRLHVD 443

Query: 1235 QRSCTDIDECEDNPNICDGGQCTNIPGEYRCLCYDGFMASEDMKTCVDVNECDLNPNICL 1294
             R+C  +  C      C+        G + C C  G+  ++D K+C + N C  +   C 
Sbjct: 442  ARTCIAVSGCSVXNGGCEHVCTDGYNGHFHCRCRPGYTLAQDGKSCQEDNPCQHSNGGCQ 263

Query: 1295 SGTCENTKGSFICHCDMGYSGKKGKTGCTDINECEIGAHNCGRHAVCTNTAGSFKCSCSP 1354
              TC + +G  +C C  GY        C DI+EC     +C +   C NT GSF C+C+ 
Sbjct: 262  H-TCVSDRGRAVCRCFQGYELAADGRSCKDIDECAKRNGDCLQR--CVNTQGSFTCTCTQ 92

Query: 1355 GW 1356
            G+
Sbjct: 91   GY 86

 Score = 97.4 bits (241), Expect = 8e-20,   Method: Compositional matrix adjust.
 Identities = 73/194 (37%), Positives = 100/194 (51%), Gaps = 6/194 (3%)
 Frame = -2

Query: 1786 NMVGSFRCECPVGFFYNDKLLVCEDIDEC--QNGPVCQRNAECINTAGSYRCDCKPGYRL 1843
            N  GS+RC C +GF   + +  C D+DEC   NG  CQ   +C+NT G + C+C  G RL
Sbjct: 622  NTAGSYRCRCSMGFELAEDMKSCLDVDECVSHNGG-CQH--KCVNTYGGFNCECPKGQRL 452

Query: 1844 TSTGQ-CNDRNECQEIPNICSHGQCIDTV-GSFYCLCHTGFKTNVDQTMCLDINECERDA 1901
                + C   + C      C H  C D   G F+C C  G+    D   C + N C+   
Sbjct: 451  HVDARTCIAVSGCSVXNGGCEH-VCTDGYNGHFHCRCRPGYTLAQDGKSCQEDNPCQHSN 275

Query: 1902 CG-NGTCRNTIGSFNCRCNHGFILSHN-NDCIDVDECATGNGNLCRNGQCVNTVGSFQCR 1959
             G   TC +  G   CRC  G+ L+ +   C D+DECA  NG+  +  +CVNT GSF C 
Sbjct: 274  GGCQHTCVSDRGRAVCRCFQGYELAADGRSCKDIDECAKRNGDCLQ--RCVNTQGSFTCT 101

Query: 1960 CNEGYEVAPDGRTC 1973
            C +GY++  DGR+C
Sbjct: 100  CTQGYQLGNDGRSC 59

 Score = 92.8 bits (229), Expect = 2e-18,   Method: Compositional matrix adjust.
 Identities = 57/153 (37%), Positives = 85/153 (55%), Gaps = 3/153 (1%)
 Frame = -2

Query: 1909 NTIGSFNCRCNHGFILSHN-NDCIDVDECATGNGNLCRNGQCVNTVGSFQCRCNEGYEVA 1967
            NT GS+ CRC+ GF L+ +   C+DVDEC + NG  C++ +CVNT G F C C +G  + 
Sbjct: 622  NTAGSYRCRCSMGFELAEDMKSCLDVDECVSHNGG-CQH-KCVNTYGGFNCECPKGQRLH 449

Query: 1968 PDGRTCVDINECVLDPGKCAPGTCQNLDGSYRCICPPGYSLQND--KCEDIDECVEEPEI 2025
             D RTC+ ++ C +  G C        +G + C C PGY+L  D   C++ + C      
Sbjct: 448  VDARTCIAVSGCSVXNGGCEHVCTDGYNGHFHCRCRPGYTLAQDGKSCQEDNPCQHSNGG 269

Query: 2026 CALGTCSNTEGSFKCLCPEGFSLSSTGRRCQDL 2058
            C   TC +  G   C C +G+ L++ GR C+D+
Sbjct: 268  CQH-TCVSDRGRAVCRCFQGYELAADGRSCKDI 173

 Score = 89.4 bits (220), Expect = 2e-17,   Method: Compositional matrix adjust.
 Identities = 66/193 (34%), Positives = 87/193 (45%), Gaps = 4/193 (2%)
 Frame = -2

Query: 1216 NSDGSYECSCQPGFALMPDQRSCTDIDECEDNPNICDGGQCTNIPGEYRCLCYDGFMASE 1275
            N+ GSY C C  GF L  D +SC D+DEC  +   C   +C N  G + C C  G     
Sbjct: 622  NTAGSYRCRCSMGFELAEDMKSCLDVDECVSHNGGCQH-KCVNTYGGFNCECPKGQRLHV 446

Query: 1276 DMKTCVDVNECDLNPNICLSGTCENTKGSFICHCDMGYSGKKGKTGCTDINECEIGAHNC 1335
            D +TC+ V+ C +    C     +   G F C C  GY+  +    C + N C+    N 
Sbjct: 445  DARTCIAVSGCSVXNGGCEHVCTDGYNGHFHCRCRPGYTLAQDGKSCQEDNPCQ--HSNG 272

Query: 1336 GRHAVCTNTAGSFKCSCSPGW--IGDGIKCTDLDECSNGTHMCSQHADCKNTMGSYRCLC 1393
            G    C +  G   C C  G+    DG  C D+DEC+     C Q   C NT GS+ C C
Sbjct: 271  GCQHTCVSDRGRAVCRCFQGYELAADGRSCKDIDECAKRNGDCLQR--CVNTQGSFTCTC 98

Query: 1394 KDGYT--GDGFTC 1404
              GY    DG +C
Sbjct: 97   TQGYQLGNDGRSC 59

 Score = 84.3 bits (207), Expect = 6e-16,   Method: Compositional matrix adjust.
 Identities = 69/206 (33%), Positives = 92/206 (44%), Gaps = 4/206 (1%)
 Frame = -2

Query: 1343 NTAGSFKCSCSPGW--IGDGIKCTDLDECSNGTHMCSQHADCKNTMGSYRCLCKDG--YT 1398
            NTAGS++C CS G+    D   C D+DEC +    C QH  C NT G + C C  G    
Sbjct: 622  NTAGSYRCRCSMGFELAEDMKSCLDVDECVSHNGGC-QHK-CVNTYGGFNCECPKGQRLH 449

Query: 1399 GDGFTCTDLDECSEXXXXXXXXXXXXAPGGYRCECDMGFVPSADGKACEDIDECSLPNIC 1458
             D  TC  +  CS               G + C C  G+  + DGK+C++ + C   N  
Sbjct: 448  VDARTCIAVSGCSVXNGGCEHVCTDGYNGHFHCRCRPGYTLAQDGKSCQEDNPCQHSNGG 269

Query: 1459 VFGTCHNLPGLFRCECEIGYELDRSGGNCTDVNECLDPTTCISGNCVNTPGSYTCDCPPD 1518
               TC +  G   C C  GYEL   G +C D++EC          CVNT GS+TC C   
Sbjct: 268  CQHTCVSDRGRAVCRCFQGYELAADGRSCKDIDECAKRNGDCLQRCVNTQGSFTCTCTQG 89

Query: 1519 FELNPTRVGCVDTRSGNCYLDIRPRG 1544
            ++L      C    + N     +P G
Sbjct: 88   YQLGNDGRSCYIMPAANVTNTPKPPG 11

 Score = 83.2 bits (204), Expect = 1e-15,   Method: Compositional matrix adjust.
 Identities = 72/227 (31%), Positives = 97/227 (42%), Gaps = 4/227 (1%)
 Frame = -2

Query: 1299 ENTKGSFICHCDMGYSGKKGKTGCTDINECEIGAHNCGRHAVCTNTAGSFKCSCSPG--W 1356
            ENT GS+ C C MG+   +    C D++EC   +HN G    C NT G F C C  G   
Sbjct: 625  ENTAGSYRCRCSMGFELAEDMKSCLDVDECV--SHNGGCQHKCVNTYGGFNCECPKGQRL 452

Query: 1357 IGDGIKCTDLDECSNGTHMCSQHADCKNTMGSYRCLCKDGYT--GDGFTCTDLDECSEXX 1414
              D   C  +  CS     C +H       G + C C+ GYT   DG +C + + C +  
Sbjct: 451  HVDARTCIAVSGCSVXNGGC-EHVCTDGYNGHFHCRCRPGYTLAQDGKSCQEDNPC-QHS 278

Query: 1415 XXXXXXXXXXAPGGYRCECDMGFVPSADGKACEDIDECSLPNICVFGTCHNLPGLFRCEC 1474
                        G   C C  G+  +ADG++C+DIDEC+  N      C N  G F C C
Sbjct: 277  NGGCQHTCVSDRGRAVCRCFQGYELAADGRSCKDIDECAKRNGDCLQRCVNTQGSFTCTC 98

Query: 1475 EIGYELDRSGGNCTDVNECLDPTTCISGNCVNTPGSYTCDCPPDFEL 1521
              GY+L   G +C  +          + N  NTP       PP  E+
Sbjct: 97   TQGYQLGNDGRSCYIM---------PAANVTNTPK------PPGIEM 2

 Score = 83.2 bits (204), Expect = 2e-15,   Method: Compositional matrix adjust.
 Identities = 67/208 (32%), Positives = 84/208 (40%), Gaps = 1/208 (0%)
 Frame = -2

Query: 2311 NTLGSYTCECNDGFTASPTQDECLDNREGYCFSEVLQNMCQIGSSNRNPVTKSECCCDGG 2370
            NT GSY C C+ GF  +     CLD  E    +   Q+ C       N      C C  G
Sbjct: 622  NTAGSYRCRCSMGFELAEDMKSCLDVDECVSHNGGCQHKCV------NTYGGFNCECPKG 461

Query: 2371 RGWGPHCEIC-PFEGTVAYKKLCPHGRGFMTNGADIDECKVIHDVCRNGECVNDRGSYHC 2429
            +        C    G       C H                   VC +G      G +HC
Sbjct: 460  QRLHVDARTCIAVSGCSVXNGGCEH-------------------VCTDGY----NGHFHC 350

Query: 2430 ICKTGYTPDITGTACVDLNECNQAPKPCNFICKNTEGSYQCSCPKGYILQEDGRSCKDLD 2489
             C+ GYT    G +C + N C  +   C   C +  G   C C +GY L  DGRSCKD+D
Sbjct: 349  RCRPGYTLAQDGKSCQEDNPCQHSNGGCQHTCVSDRGRAVCRCFQGYELAADGRSCKDID 170

Query: 2490 ECATKQHNCQFLCVNTIGGFTCKCPPGF 2517
            ECA +  +C   CVNT G FTC C  G+
Sbjct: 169  ECAKRNGDCLQRCVNTQGSFTCTCTQGY 86

 Score = 80.5 bits (197), Expect = 9e-15,   Method: Compositional matrix adjust.
 Identities = 53/155 (34%), Positives = 78/155 (50%), Gaps = 7/155 (4%)
 Frame = -2

Query: 466 RCIPTPGSYRCECNKGFQLDIRGE-CIDVDECE------KNPCTGGECINNQGSYTCHCR 518
           +C+ T G + CEC KG +L +    CI V  C       ++ CT G      G + C CR
Sbjct: 508 KCVNTYGGFNCECPKGQRLHVDARTCIAVSGCSVXNGGCEHVCTDGY----NGHFHCRCR 341

Query: 519 AGYQSTLTRTECRDIDECLQNGRICNNGRCINTDGSFHCVCNAGFHVTRDGKNCEDMDEC 578
            GY        C++ + C  +   C +  C++  G   C C  G+ +  DG++C+D+DEC
Sbjct: 340 PGYTLAQDGKSCQEDNPCQHSNGGCQH-TCVSDRGRAVCRCFQGYELAADGRSCKDIDEC 164

Query: 579 SIRNMCLNGMCINEDGSFKCICKPGFQLASDGRYC 613
           + RN      C+N  GSF C C  G+QL +DGR C
Sbjct: 163 AKRNGDCLQRCVNTQGSFTCTCTQGYQLGNDGRSC 59

 Score = 79.3 bits (194), Expect = 2e-14,   Method: Compositional matrix adjust.
 Identities = 72/218 (33%), Positives = 100/218 (45%), Gaps = 6/218 (2%)
 Frame = -2

Query: 742 ENLRGTYKCICNSGYEVDITGKNCVDINECVLNSLLCDNGQCRNTPGSFVCTCPKGFVYK 801
           EN  G+Y+C C+ G+E+    K+C+D++ECV ++  C + +C NT G F C CPKG    
Sbjct: 625 ENTAGSYRCRCSMGFELAEDMKSCLDVDECVSHNGGCQH-KCVNTYGGFNCECPKGQRLH 449

Query: 802 PDLKTCEDIDECESSPCINGVCKNS-----PGSFICECSPESTLDPTKTICIETIKGTCW 856
            D +TC  +  C      NG C++       G F C C P  TL      C E       
Sbjct: 448 VDARTCIAVSGCSVX---NGGCEHVCTDGYNGHFHCRCRPGYTLAQDGKSCQE------- 299

Query: 857 QTVIDGRCEININGATLKSECCSSLGAAWGSPCTICQLDPICGKGFS-RIKGTQCEDINE 915
               D  C+ +  G   +  C S  G A      +C+    C +G+     G  C+DI+E
Sbjct: 298 ----DNPCQHSNGGC--QHTCVSDRGRA------VCR----CFQGYELAADGRSCKDIDE 167

Query: 916 CEVFPGVCKNGLCVNSRGSFKCECPNGMTLDATGRICL 953
           C    G C    CVN++GSF C C  G  L   GR C 
Sbjct: 166 CAKRNGDCLQ-RCVNTQGSFTCTCTQGYQLGNDGRSCY 56

 Score = 78.2 bits (191), Expect = 5e-14,   Method: Compositional matrix adjust.
 Identities = 62/206 (30%), Positives = 87/206 (42%), Gaps = 6/206 (2%)
 Frame = -2

Query: 2504 NTIGGFTCKCPPGF--TQHHTACIDNNECTSDINLCGSKGVCQNTPGSFTCECQRGFSLD 2561
            NT G + C+C  GF   +   +C+D +EC S    C  K  C NT G F CEC +G  L 
Sbjct: 622  NTAGSYRCRCSMGFELAEDMKSCLDVDECVSHNGGCQHK--CVNTYGGFNCECPKGQRLH 449

Query: 2562 QSGASCEDVDECE-GNHRCQHGCQNIIGG-YRCSCPQGYLQHYQWNQCVDENECLSAHVC 2619
                +C  V  C   N  C+H C +   G + C C  GY        C ++N C  ++  
Sbjct: 448  VDARTCIAVSGCSVXNGGCEHVCTDGYNGHFHCRCRPGYTLAQDGKSCQEDNPCQHSNGG 269

Query: 2620 GGASCHNTLGSYKCMCPTGFQYEQFSGGCQDINECGSSQAPCSYGCSNTEGGYLCGCPPG 2679
               +C +  G   C C  G++       C+DI+EC      C   C NT+G + C C  G
Sbjct: 268  CQHTCVSDRGRAVCRCFQGYELAADGRSCKDIDECAKRNGDCLQRCVNTQGSFTCTCTQG 89

Query: 2680 YFRIGQGHC--VSXXXXXXXXPEPPA 2703
            Y     G    +         P+PP 
Sbjct: 88   YQLGNDGRSCYIMPAANVTNTPKPPG 11

 Score = 77.4 bits (189), Expect = 7e-14,   Method: Compositional matrix adjust.
 Identities = 64/221 (28%), Positives = 92/221 (41%), Gaps = 4/221 (1%)
 Frame = -2

Query: 591 NEDGSFKCICKPGFQLASDGRYCKDINECETPGICMNGRCVNTDGSYRCECFPGLAVGLD 650
           N  GS++C C  GF+LA D + C D++EC +       +CVNT G + CEC  G  + +D
Sbjct: 622 NTAGSYRCRCSMGFELAEDMKSCLDVDECVSHNGGCQHKCVNTYGGFNCECPKGQRLHVD 443

Query: 651 GRVCVDTHMRSTCYGGYRRGQCVKPLFGAVTKSECCCASTEYAFGEPCQPCPAQNSAEYQ 710
            R C+     S   GG                                  C    +  + 
Sbjct: 442 ARTCIAVSGCSVXNGGCE------------------------------HVCTDGYNGHFH 353

Query: 711 ALCSSGPGMTSAGTDINECALDPDICPNGICENL----RGTYKCICNSGYEVDITGKNCV 766
             C  G  +   G    E   +P    NG C++     RG   C C  GYE+   G++C 
Sbjct: 352 CRCRPGYTLAQDGKSCQE--DNPCQHSNGGCQHTCVSDRGRAVCRCFQGYELAADGRSCK 179

Query: 767 DINECVLNSLLCDNGQCRNTPGSFVCTCPKGFVYKPDLKTC 807
           DI+EC   +  C   +C NT GSF CTC +G+    D ++C
Sbjct: 178 DIDECAKRNGDCLQ-RCVNTQGSFTCTCTQGYQLGNDGRSC 59

 Score = 77.4 bits (189), Expect = 8e-14,   Method: Compositional matrix adjust.
 Identities = 59/183 (32%), Positives = 82/183 (44%), Gaps = 4/183 (2%)
 Frame = -2

Query: 2146 NTDGSYRCECPFGYIL--EGNECVDTDECSVGNPCGNGTCKNVIXXXX-XXXXXXXXXXX 2202
            NT GSYRC C  G+ L  +   C+D DEC   N      C N                  
Sbjct: 622  NTAGSYRCRCSMGFELAEDMKSCLDVDECVSHNGGCQHKCVNTYGGFNCECPKGQRLHVD 443

Query: 2203 MMTCEDINECAQNPLLCAFRCVNTY-GSYECKCPVGYVLREDRRMCKDEDECAEGKHDCT 2261
              TC  ++ C+     C   C + Y G + C+C  GY L +D + C++++ C      C 
Sbjct: 442  ARTCIAVSGCSVXNGGCEHVCTDGYNGHFHCRCRPGYTLAQDGKSCQEDNPCQHSNGGC- 266

Query: 2262 EKQMECKNLIGTYMCICGPGYQRRPDGEGCIDENECQTKPGICENGRCLNTLGSYTCECN 2321
              Q  C +  G  +C C  GY+   DG  C D +EC  + G C   RC+NT GS+TC C 
Sbjct: 265  --QHTCVSDRGRAVCRCFQGYELAADGRSCKDIDECAKRNGDCLQ-RCVNTQGSFTCTCT 95

Query: 2322 DGF 2324
             G+
Sbjct: 94   QGY 86

 Score = 74.7 bits (182), Expect = 5e-13,   Method: Compositional matrix adjust.
 Identities = 65/218 (29%), Positives = 97/218 (44%)
 Frame = -2

Query: 2268 KNLIGTYMCICGPGYQRRPDGEGCIDENECQTKPGICENGRCLNTLGSYTCECNDGFTAS 2327
            +N  G+Y C C  G++   D + C+D +EC +  G C++ +C+NT G + CEC  G    
Sbjct: 625  ENTAGSYRCRCSMGFELAEDMKSCLDVDECVSHNGGCQH-KCVNTYGGFNCECPKGQRLH 449

Query: 2328 PTQDECLDNREGYCFSEVLQNMCQIGSSNRNPVTKSECCCDGGRGWGPHCEICPFEGTVA 2387
                 C           +  + C + +     V     C DG  G   HC   P      
Sbjct: 448  VDARTC-----------IAVSGCSVXNGGCEHV-----CTDGYNGH-FHCRCRPGYTLAQ 320

Query: 2388 YKKLCPHGRGFMTNGADIDECKVIHDVCRNGECVNDRGSYHCICKTGYTPDITGTACVDL 2447
              K C           + + C+  +  C++  CV+DRG   C C  GY     G +C D+
Sbjct: 319  DGKSCQ----------EDNPCQHSNGGCQH-TCVSDRGRAVCRCFQGYELAADGRSCKDI 173

Query: 2448 NECNQAPKPCNFICKNTEGSYQCSCPKGYILQEDGRSC 2485
            +EC +    C   C NT+GS+ C+C +GY L  DGRSC
Sbjct: 172  DECAKRNGDCLQRCVNTQGSFTCTCTQGYQLGNDGRSC 59

 Score = 73.2 bits (178), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 56/165 (33%), Positives = 77/165 (46%), Gaps = 4/165 (2%)
 Frame = -2

Query: 1767 VDIDECREIPGVCENGVCINMVGSFRCECPVGFFYNDKLLVCEDIDECQ--NGPVCQRNA 1824
            +D+DEC    G C++  C+N  G F CECP G   +     C  +  C   NG       
Sbjct: 553  LDVDECVSHNGGCQH-KCVNTYGGFNCECPKGQRLHVDARTCIAVSGCSVXNGGCEHVCT 377

Query: 1825 ECINTAGSYRCDCKPGYRLTSTGQ-CNDRNECQEIPNICSHGQCIDTVGSFYCLCHTGFK 1883
            +  N  G + C C+PGY L   G+ C + N CQ     C H  C+   G   C C  G++
Sbjct: 376  DGYN--GHFHCRCRPGYTLAQDGKSCQEDNPCQHSNGGCQH-TCVSDRGRAVCRCFQGYE 206

Query: 1884 TNVDQTMCLDINEC-ERDACGNGTCRNTIGSFNCRCNHGFILSHN 1927
               D   C DI+EC +R+      C NT GSF C C  G+ L ++
Sbjct: 205  LAADGRSCKDIDECAKRNGDCLQRCVNTQGSFTCTCTQGYQLGND 71

 Score = 72.4 bits (176), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 59/175 (33%), Positives = 81/175 (46%), Gaps = 9/175 (5%)
 Frame = -2

Query: 2126 SAVDMDECKEPDV-CRHGQCINTDGSYRCECPFGYIL--EGNECVDTDECSVGNPCGNGT 2182
            S +D+DEC   +  C+H +C+NT G + CECP G  L  +   C+    CSV N    G 
Sbjct: 559  SCLDVDECVSHNGGCQH-KCVNTYGGFNCECPKGQRLHVDARTCIAVSGCSVXN----GG 395

Query: 2183 CKNVIXXXXXXXXX------XXXXXXMMTCEDINECAQNPLLCAFRCVNTYGSYECKCPV 2236
            C++V                        +C++ N C  +   C   CV+  G   C+C  
Sbjct: 394  CEHVCTDGYNGHFHCRCRPGYTLAQDGKSCQEDNPCQHSNGGCQHTCVSDRGRAVCRCFQ 215

Query: 2237 GYVLREDRRMCKDEDECAEGKHDCTEKQMECKNLIGTYMCICGPGYQRRPDGEGC 2291
            GY L  D R CKD DECA+   DC ++   C N  G++ C C  GYQ   DG  C
Sbjct: 214  GYELAADGRSCKDIDECAKRNGDCLQR---CVNTQGSFTCTCTQGYQLGNDGRSC 59

 Score = 70.5 bits (171), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 65/230 (28%), Positives = 88/230 (38%), Gaps = 2/230 (0%)
 Frame = -2

Query: 1465 NLPGLFRCECEIGYELDRSGGNCTDVNECLDPTTCISGNCVNTPGSYTCDCPPDFELNPT 1524
            N  G +RC C +G+EL     +C DV+EC+         CVNT G + C+CP    L+  
Sbjct: 622  NTAGSYRCRCSMGFELAEDMKSCLDVDECVSHNGGCQHKCVNTYGGFNCECPKGQRLH-- 449

Query: 1525 RVGCVDTRSGNCYLDIRPRGDNGDTACSNEIGVGVSKASC--CCSLGKAWGTPCELCPSV 1582
                VD R+                 C    G  V    C   C+ G      C   P  
Sbjct: 448  ----VDART-----------------CIAVSGCSVXNGGCEHVCTDGYNGHFHCRCRPGY 332

Query: 1583 NTSEYKILCPGGEGFRPNPITVILEDIDECQELPGLCQGGKCINTFGSFQCRCPTGYYLN 1642
              ++    C               ++ + CQ   G CQ   C++  G   CRC  GY L 
Sbjct: 331  TLAQDGKSC---------------QEDNPCQHSNGGCQH-TCVSDRGRAVCRCFQGYELA 200

Query: 1643 EDTRVCDDVNECETPGICGPGTCYNTVGNYTCICPPDYMQVNGGNNCMDM 1692
             D R C D++EC          C NT G++TC C   Y   N G +C  M
Sbjct: 199  ADGRSCKDIDECAKRNGDCLQRCVNTQGSFTCTCTQGYQLGNDGRSCYIM 50

 Score = 69.7 bits (169), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 54/178 (30%), Positives = 76/178 (42%)
 Frame = -2

Query: 1030 DINECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQCV 1089
            D++EC      C H KC NT G F C C  G  L  + R C  +  C +    C      
Sbjct: 550  DVDECVSHNGGCQH-KCVNTYGGFNCECPKGQRLHVDARTCIAVSGCSVXNGGCEHVCTD 374

Query: 1090 NTPGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRGGICHNTEGSYRCECPPGHQLS 1149
               G F C+C  GY       K+C + + CQ     C+   C +  G   C C  G++L+
Sbjct: 373  GYNGHFHCRCRPGYTLA-QDGKSCQEDNPCQHSNGGCQ-HTCVSDRGRAVCRCFQGYELA 200

Query: 1150 PNISACIDINECELSANLCPHGRCVNLIGKYQCACNPGYHPTHDRLFCVDIDECSIMN 1207
             +  +C DI+EC      C   RCVN  G + C C  GY   +D   C  +   ++ N
Sbjct: 199  ADGRSCKDIDECAKRNGDCLQ-RCVNTQGSFTCTCTQGYQLGNDGRSCYIMPAANVTN 29

 Score = 69.3 bits (168), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 72/235 (30%), Positives = 96/235 (40%), Gaps = 3/235 (1%)
 Frame = -2

Query: 2225 NTYGSYECKCPVGYVLREDRRMCKDEDECAEGKHDCTEKQMECKNLIGTYMCICGPGYQR 2284
            NT GSY C+C +G+ L ED + C D DEC      C   Q +C N  G + C C  G + 
Sbjct: 622  NTAGSYRCRCSMGFELAEDMKSCLDVDECVSHNGGC---QHKCVNTYGGFNCECPKGQRL 452

Query: 2285 RPDGEGCIDENECQTKPGICENGRCLNTLGSYTCECNDGFTASPTQDECLDNREGYCFSE 2344
              D   CI  + C    G CE+       G + C C  G+T +     C ++        
Sbjct: 451  HVDARTCIAVSGCSVXNGGCEHVCTDGYNGHFHCRCRPGYTLAQDGKSCQED-------- 296

Query: 2345 VLQNMCQIGSSNRNPVTKSECCCDGGRGWGPHCEICP-FEGTVAYKKLCPHGRGFMTNGA 2403
               N CQ    + N   +  C  D GR       +C  F+G     +L   GR       
Sbjct: 295  ---NPCQ----HSNGGCQHTCVSDRGRA------VCRCFQGY----ELAADGRSC----K 179

Query: 2404 DIDECKVIHDVCRNGECVNDRGSYHCICKTGYTPDITGTACVDLNECN--QAPKP 2456
            DIDEC   +  C    CVN +GS+ C C  GY     G +C  +   N    PKP
Sbjct: 178  DIDECAKRNGDCLQ-RCVNTQGSFTCTCTQGYQLGNDGRSCYIMPAANVTNTPKP 17

 Score = 69.3 bits (168), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 65/222 (29%), Positives = 92/222 (41%), Gaps = 6/222 (2%)
 Frame = -2

Query: 550 NTDGSFHCVCNAGFHVTRDGKNCEDMDECSIRNMCLNGMCINEDGSFKCICKPGFQLASD 609
           NT GS+ C C+ GF +  D K+C D+DEC   N      C+N  G F C C  G +L  D
Sbjct: 622 NTAGSYRCRCSMGFELAEDMKSCLDVDECVSHNGGCQHKCVNTYGGFNCECPKGQRLHVD 443

Query: 610 GRYCKDINECETPGICMNGRCVNT-----DGSYRCECFPGLAVGLDGRVCVDTHMRSTCY 664
            R C  ++ C       NG C +      +G + C C PG  +  DG+ C + +      
Sbjct: 442 ARTCIAVSGCSV----XNGGCEHVCTDGYNGHFHCRCRPGYTLAQDGKSCQEDNPCQHSN 275

Query: 665 GGYRRGQCVKPLFGAVTKSECCCASTEYAF-GEPCQPCPAQNSAEYQALCSSGPGMTSAG 723
           GG +   CV     AV +   C    E A  G  C+                        
Sbjct: 274 GGCQH-TCVSDRGRAVCR---CFQGYELAADGRSCK------------------------ 179

Query: 724 TDINECALDPDICPNGICENLRGTYKCICNSGYEVDITGKNC 765
            DI+ECA     C    C N +G++ C C  GY++   G++C
Sbjct: 178 -DIDECAKRNGDCLQ-RCVNTQGSFTCTCTQGYQLGNDGRSC 59

 Score = 65.9 bits (159), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 65/226 (28%), Positives = 93/226 (41%), Gaps = 3/226 (1%)
 Frame = -2

Query: 1626 NTFGSFQCRCPTGYYLNEDTRVCDDVNECETPGICGPGTCYNTVGNYTCICPPDYMQVNG 1685
            NT GS++CRC  G+ L ED + C DV+EC +        C NT G + C CP        
Sbjct: 622  NTAGSYRCRCSMGFELAEDMKSCLDVDECVSHNGGCQHKCVNTYGGFNCECPKG------ 461

Query: 1686 GNNCMDMRRSLCYRNYYADNQTCDGELLFNMTKKMCCCSYNIGRAWNKPCEQ-CPIPSTD 1744
                         +  + D +TC       +    C          N  CE  C      
Sbjct: 460  -------------QRLHVDARTC-------IAVSGC-------SVXNGGCEHVCTDGYNG 362

Query: 1745 EFATLCGSQRPGFVIDIYTGLPVDIDECREIPGVCENGVCINMVGSFRCECPVGFFYNDK 1804
             F   C   RPG+ +        + + C+   G C++  C++  G   C C  G+     
Sbjct: 361  HFHCRC---RPGYTLAQDGKSCQEDNPCQHSNGGCQH-TCVSDRGRAVCRCFQGYELAAD 194

Query: 1805 LLVCEDIDEC--QNGPVCQRNAECINTAGSYRCDCKPGYRLTSTGQ 1848
               C+DIDEC  +NG   QR   C+NT GS+ C C  GY+L + G+
Sbjct: 193  GRSCKDIDECAKRNGDCLQR---CVNTQGSFTCTCTQGYQLGNDGR 65

 Score = 62.0 bits (149), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 63/210 (30%), Positives = 87/210 (41%), Gaps = 1/210 (0%)
 Frame = -2

Query: 898  CGKGFSRIKGTQ-CEDINECEVFPGVCKNGLCVNSRGSFKCECPNGMTLDATGRICLDIR 956
            C  GF   +  + C D++EC    G C++  CVN+ G F CECP G  L    R C+ + 
Sbjct: 595  CSMGFELAEDMKSCLDVDECVSHNGGCQH-KCVNTYGGFNCECPKGQRLHVDARTCIAV- 422

Query: 957  LETCFLKYDDEECTLPIAGRHRMDACCCSVGAAWGTEECEECPLRNSREYEELCPRGPGF 1016
                        C++   G        C      G      C  R            PG+
Sbjct: 421  ----------SGCSVXNGG--------CEHVCTDGYNGHFHCRCR------------PGY 332

Query: 1017 ATKDITNGKPFFKDINECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDEC 1076
                  +GK   +D N C+     C H  C +  G   CRC  G+ L ++ R+C DIDEC
Sbjct: 331  TLAQ--DGKSCQED-NPCQHSNGGCQH-TCVSDRGRAVCRCFQGYELAADGRSCKDIDEC 164

Query: 1077 RISPDLCGRGQCVNTPGDFECKCDEGYESG 1106
                  C + +CVNT G F C C +GY+ G
Sbjct: 163  AKRNGDCLQ-RCVNTQGSFTCTCTQGYQLG 77

 Score = 61.2 bits (147), Expect = 5e-09,   Method: Compositional matrix adjust.
 Identities = 40/117 (34%), Positives = 57/117 (48%), Gaps = 6/117 (5%)
 Frame = -2

Query: 472 GSYRCECNKGFQLDIRGECIDVDECEKNPC---TGG---ECINNQGSYTCHCRAGYQSTL 525
           G + C C  G+ L   G+       E NPC    GG    C++++G   C C  GY+   
Sbjct: 364 GHFHCRCRPGYTLAQDGKSCQ----EDNPCQHSNGGCQHTCVSDRGRAVCRCFQGYELAA 197

Query: 526 TRTECRDIDECLQNGRICNNGRCINTDGSFHCVCNAGFHVTRDGKNCEDMDECSIRN 582
               C+DIDEC +    C   RC+NT GSF C C  G+ +  DG++C  M   ++ N
Sbjct: 196 DGRSCKDIDECAKRNGDCLQ-RCVNTQGSFTCTCTQGYQLGNDGRSCYIMPAANVTN 29

 Score = 59.3 bits (142), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 37/104 (35%), Positives = 54/104 (51%), Gaps = 1/104 (0%)
 Frame = -2

Query: 231 CRRGFIPNIRTGACQDVDECQAIPGMCQGGNCINTVGSFECKCPAGHKFNEVSQKCEDID 290
           C  GF       +C DVDEC +  G CQ   C+NT G F C+CP G + +  ++ C  + 
Sbjct: 595 CSMGFELAEDMKSCLDVDECVSHNGGCQH-KCVNTYGGFNCECPKGQRLHVDARTCIAVS 419

Query: 291 ECSTIPGVCDGGECTNTVSSYF-CKCPPGFYTSPDGTRCVDVRP 333
            CS   G C+   CT+  + +F C+C PG+  + DG  C +  P
Sbjct: 418 GCSVXNGGCE-HVCTDGYNGHFHCRCRPGYTLAQDGKSCQEDNP 290

 Score = 56.6 bits (135), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 74/266 (27%), Positives = 92/266 (34%), Gaps = 10/266 (3%)
 Frame = -2

Query: 1992 QNLDGSYRCICPPGYSLQND--KCEDIDECVEEPEICALGTCSNTEGSFKCLCPEGFSLS 2049
            +N  GSYRC C  G+ L  D   C D+DECV     C    C NT G F C CP+G  L 
Sbjct: 625  ENTAGSYRCRCSMGFELAEDMKSCLDVDECVSHNGGCQH-KCVNTYGGFNCECPKGQRLH 449

Query: 2050 STGRRCQDLRMSYCYAKFEGGKCSSPKSRNHSKQECCCALKGEGWGDPCELCPTEPDEAF 2109
               R C  + +S C      G C                           +C    +  F
Sbjct: 448  VDARTC--IAVSGC--SVXNGGCE-------------------------HVCTDGYNGHF 356

Query: 2110 RQICPFGSGIIVGPDDSAVDMDECKEPDVCRHGQ------CINTDGSYRCECPFGYIL-- 2161
               C  G  +       A D   C+E + C+H        C++  G   C C  GY L  
Sbjct: 355  HCRCRPGYTL-------AQDGKSCQEDNPCQHSNGGCQHTCVSDRGRAVCRCFQGYELAA 197

Query: 2162 EGNECVDTDECSVGNPCGNGTCKNVIXXXXXXXXXXXXXXXMMTCEDINECAQNPLLCAF 2221
            +G  C D DEC+  N                                  +C Q       
Sbjct: 196  DGRSCKDIDECAKRN---------------------------------GDCLQ------- 137

Query: 2222 RCVNTYGSYECKCPVGYVLREDRRMC 2247
            RCVNT GS+ C C  GY L  D R C
Sbjct: 136  RCVNTQGSFTCTCTQGYQLGNDGRSC 59

 Score = 50.1 bits (118), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 33/98 (33%), Positives = 47/98 (47%)
 Frame = -2

Query: 231 CRRGFIPNIRTGACQDVDECQAIPGMCQGGNCINTVGSFECKCPAGHKFNEVSQKCEDID 290
           CR G+       +CQ+ + CQ   G CQ   C++  G   C+C  G++     + C+DID
Sbjct: 346 CRPGYTLAQDGKSCQEDNPCQHSNGGCQH-TCVSDRGRAVCRCFQGYELAADGRSCKDID 170

Query: 291 ECSTIPGVCDGGECTNTVSSYFCKCPPGFYTSPDGTRC 328
           EC+   G C    C NT  S+ C C  G+    DG  C
Sbjct: 169 ECAKRNGDCL-QRCVNTQGSFTCTCTQGYQLGNDGRSC 59

 Score = 49.7 bits (117), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 30/98 (30%), Positives = 45/98 (45%), Gaps = 1/98 (1%)
 Frame = -2

Query: 2584 QNIIGGYRCSCPQGYLQHYQWNQCVDENECLSAHVCGGASCHNTLGSYKCMCPTGFQYEQ 2643
            +N  G YRC C  G+        C+D +EC+S +      C NT G + C CP G +   
Sbjct: 625  ENTAGSYRCRCSMGFELAEDMKSCLDVDECVSHNGGCQHKCVNTYGGFNCECPKGQRLHV 446

Query: 2644 FSGGCQDINECGSSQAPCSYGCSNTEGGYL-CGCPPGY 2680
             +  C  ++ C      C + C++   G+  C C PGY
Sbjct: 445  DARTCIAVSGCSVXNGGCEHVCTDGYNGHFHCRCRPGY 332

 Score = 48.1 bits (113), Expect = 6e-05,   Method: Compositional matrix adjust.
 Identities = 25/68 (36%), Positives = 35/68 (51%)
 Frame = -2

Query: 264 NTVGSFECKCPAGHKFNEVSQKCEDIDECSTIPGVCDGGECTNTVSSYFCKCPPGFYTSP 323
           NT GS+ C+C  G +  E  + C D+DEC +  G C   +C NT   + C+CP G     
Sbjct: 622 NTAGSYRCRCSMGFELAEDMKSCLDVDECVSHNGGCQ-HKCVNTYGGFNCECPKGQRLHV 446

Query: 324 DGTRCVDV 331
           D   C+ V
Sbjct: 445 DARTCIAV 422

 Score = 41.2 bits (95), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 33/136 (24%), Positives = 61/136 (44%), Gaps = 7/136 (5%)
 Frame = -2

Query: 706 SAEYQALCSSGPGMT---SAGTDINECALDPDICPNGICENLRGTYKCICNSGYEVDITG 762
           +  Y+  CS G  +     +  D++EC      C +  C N  G + C C  G  + +  
Sbjct: 616 AGSYRCRCSMGFELAEDMKSCLDVDECVSHNGGCQH-KCVNTYGGFNCECPKGQRLHVDA 440

Query: 763 KNCVDINECVLNSLLCDNGQCRNTPGSFVCTCPKGFVYKPDLKTCEDIDECESSPCINGV 822
           + C+ ++ C + +  C++       G F C C  G+    D K+C++ + C+ S   NG 
Sbjct: 439 RTCIAVSGCSVXNGGCEHVCTDGYNGHFHCRCRPGYTLAQDGKSCQEDNPCQHS---NGG 269

Query: 823 CKNS----PGSFICEC 834
           C+++     G  +C C
Sbjct: 268 CQHTCVSDRGRAVCRC 221
>03773
          Length = 1046

 Score =  107 bits (267), Expect = 6e-23,   Method: Compositional matrix adjust.
 Identities = 100/335 (29%), Positives = 135/335 (40%), Gaps = 58/335 (17%)
 Frame = +2

Query: 1162 ELSANLCPHGRCVNLIGKYQCACNPGYHPTHDRLFCVDIDECSIMNGGCETFCT-NSDGS 1220
            E + N C +G C N  G + C+C+ G     D + C    E      GC + CT N+  +
Sbjct: 2    ECTNNPCVNGNCANTDGGFTCSCSSGTFLLQDGITCQVCPE-GKFGAGCSSVCTCNATNT 178

Query: 1221 YECSCQPGF----ALMPDQRSCTDIDECEDNPNICD--GGQCTNIPGEYRCLCYDGFMAS 1274
              C    GF             TDI+ECED+          C N  G Y C C DGF +S
Sbjct: 179  DTCDAVTGFCNCTTGWNGTDCATDINECEDSATCASISNSHCNNTLGGYVCACDDGFSSS 358

Query: 1275 EDM-------------------------------KTC------------VDVNECDLNPN 1291
              M                                TC            VD++EC +N +
Sbjct: 359  GGMCMPCDDTHYGTQCLQLCPCVRANTQDCDDLIGTCTCTAFWEGENCTVDIDECAVNAS 538

Query: 1292 ICLSG---TCENTKGSFICHCDMGYSGKKGKTGCTDINECEIGAHNCGRHA--VCTNTAG 1346
            IC +    TC +  G + C C  GY        CT+INEC   + N       +C ++ G
Sbjct: 539  ICQTNPHETCRDFDGGYSCDCVSGYERPSPSDNCTNINECLYASLNTCNMTTEICVDSDG 718

Query: 1347 SFKCSCSPGWIGDGIKCTDLDECSN-GTHMCSQHADCKNTMGSYRCLCKDGYTGDGFTCT 1405
            SF C C  G+      CTD+DEC++   + CS   DC N++GSY C CK  Y      CT
Sbjct: 719  SFGCECKSGFNSTSGSCTDVDECTDPALNTCSDREDCVNSVGSYTCQCKSTYVLVNXVCT 898

Query: 1406 DLDECSEXXXXXXXXXXXXAP--GGYRCECDMGFV 1438
            D +ECS+                GGYRC+C  G+ 
Sbjct: 899  DFNECSDSSLNNCTSKENCVDIIGGYRCDCKTGYA 1003

 Score = 98.6 bits (244), Expect = 3e-20,   Method: Compositional matrix adjust.
 Identities = 108/376 (28%), Positives = 157/376 (41%), Gaps = 18/376 (4%)
 Frame = +2

Query: 2211 ECAQNPLLCAFRCVNTYGSYECKCPVGYVLREDRRMCKDEDECAEGKHDCTEKQMECKNL 2270
            EC  NP +    C NT G + C C  G  L +D   C+    C EGK       +   N 
Sbjct: 2    ECTNNPCV-NGNCANTDGGFTCSCSSGTFLLQDGITCQ---VCPEGKFGAGCSSVCTCNA 169

Query: 2271 IGTYMCICGPGY---QRRPDGEGC-IDENECQTKP--GICENGRCLNTLGSYTCECNDGF 2324
              T  C    G+       +G  C  D NEC+         N  C NTLG Y C C+DGF
Sbjct: 170  TNTDTCDAVTGFCNCTTGWNGTDCATDINECEDSATCASISNSHCNNTLGGYVCACDDGF 349

Query: 2325 TASPTQDECLDNREGYCFSEVLQNMCQIGSSNRNPVTKSECCCDGGRGW-GPHCEICPFE 2383
            ++S     C+   + +  ++ LQ +C    +N          C     W G +C +    
Sbjct: 350  SSSGGM--CMPCDDTHYGTQCLQ-LCPCVRANTQDCDDLIGTCTCTAFWEGENCTV---- 508

Query: 2384 GTVAYKKLCPHGRGFMTNGADIDECKVIHDVCRNG---ECVNDRGSYHCICKTGYTPDIT 2440
                                DIDEC V   +C+      C +  G Y C C +GY     
Sbjct: 509  --------------------DIDECAVNASICQTNPHETCRDFDGGYSCDCVSGYERPSP 628

Query: 2441 GTACVDLNECNQAP-KPCNF---ICKNTEGSYQCSCPKGYILQEDGRSCKDLDECATKQH 2496
               C ++NEC  A    CN    IC +++GS+ C C  G+       SC D+DEC     
Sbjct: 629  SDNCTNINECLYASLNTCNMTTEICVDSDGSFGCECKSGF--NSTSGSCTDVDECTDPAL 802

Query: 2497 NC---QFLCVNTIGGFTCKCPPGFTQHHTACIDNNECT-SDINLCGSKGVCQNTPGSFTC 2552
            N    +  CVN++G +TC+C   +   +  C D NEC+ S +N C SK  C +  G + C
Sbjct: 803  NTCSDREDCVNSVGSYTCQCKSTYVLVNXVCTDFNECSDSSLNNCTSKENCVDIIGGYRC 982

Query: 2553 ECQRGFSLDQSGASCE 2568
            +C+ G++ + +   C 
Sbjct: 983  DCKTGYARNTTTGLCS 1030

 Score = 94.4 bits (233), Expect = 6e-19,   Method: Compositional matrix adjust.
 Identities = 117/392 (29%), Positives = 162/392 (41%), Gaps = 15/392 (3%)
 Frame = +2

Query: 812  ECESSPCINGVCKNSPGSFICECSPESTLDPTKTICIETIKGTCWQTVIDGRCEININGA 871
            EC ++PC+NG C N+ G F C CS  + L      C         Q   +G+      GA
Sbjct: 2    ECTNNPCVNGNCANTDGGFTCSCSSGTFLLQDGITC---------QVCPEGK-----FGA 139

Query: 872  TLKSECCSSLGAAWGSPCTICQLDPICGKGFSRIKGTQCE-DINECE--VFPGVCKNGLC 928
               S C  +  A     C        C  G+    GT C  DINECE         N  C
Sbjct: 140  GCSSVC--TCNATNTDTCDAVTGFCNCTTGW---NGTDCATDINECEDSATCASISNSHC 304

Query: 929  VNSRGSFKCECPNGMTLDATGRICLDIRLETCFLKYDDEECTLPIAGRHRMDACCCSVGA 988
             N+ G + C C +G +  ++G +C+                  P    H           
Sbjct: 305  NNTLGGYVCACDDGFS--SSGGMCM------------------PCDDTH----------- 391

Query: 989  AWGTEECEECPLRNSREYEELCPRGPGFAT-KDITNGKPFFKDINECKMIPSLCT---HG 1044
             +GT+  + CP    R   + C    G  T      G+    DI+EC +  S+C    H 
Sbjct: 392  -YGTQCLQLCPCV--RANTQDCDDLIGTCTCTAFWEGENCTVDIDECAVNASICQTNPHE 562

Query: 1045 KCRNTIGSFKCRCDSGFALDSEERNCTDIDEC-RISPDLCGRGQ--CVNTPGDFECKCDE 1101
             CR+  G + C C SG+   S   NCT+I+EC   S + C      CV++ G F C+C  
Sbjct: 563  TCRDFDGGYSCDCVSGYERPSPSDNCTNINECLYASLNTCNMTTEICVDSDGSFGCECKS 742

Query: 1102 GYESGFMMMKNCMDIDECQRDPLL---CRGGICHNTEGSYRCECPPGHQLSPNISACIDI 1158
            G+ S      +C D+DEC  DP L        C N+ GSY C+C   + L   +  C D 
Sbjct: 743  GFNS---TSGSCTDVDEC-TDPALNTCSDREDCVNSVGSYTCQCKSTYVLVNXV--CTDF 904

Query: 1159 NECELSA--NLCPHGRCVNLIGKYQCACNPGY 1188
            NEC  S+  N      CV++IG Y+C C  GY
Sbjct: 905  NECSDSSLNNCTSKENCVDIIGGYRCDCKTGY 1000

 Score = 92.0 bits (227), Expect = 3e-18,   Method: Compositional matrix adjust.
 Identities = 101/319 (31%), Positives = 131/319 (41%), Gaps = 21/319 (6%)
 Frame = +2

Query: 543 CNNGRCINTDGSFHCVCNAGFHVTRDGKNCEDMDECSIRNMCLNGMCINEDGSFKCICKP 602
           C NG C NTDG F C C++G  + +DG  C+   E      C +    N   +  C    
Sbjct: 20  CVNGNCANTDGGFTCSCSSGTFLLQDGITCQVCPEGKFGAGCSSVCTCNATNTDTCDAVT 199

Query: 603 GF---QLASDGRYCK-DINECETPGICM---NGRCVNTDGSYRCECFPGLAVGLDGRVCV 655
           GF       +G  C  DINECE    C    N  C NT G Y C C  G +    G +C+
Sbjct: 200 GFCNCTTGWNGTDCATDINECEDSATCASISNSHCNNTLGGYVCACDDGFSSS--GGMCM 373

Query: 656 ---DTHMRSTCYGGYRRGQCVKPLFGAVTKSECCCASTEYAFGEPCQPCPAQNSAEYQAL 712
              DTH  + C    +   CV+            C  T +  GE C              
Sbjct: 374 PCDDTHYGTQC---LQLCPCVRANTQDCDDLIGTCTCTAFWEGENCT------------- 505

Query: 713 CSSGPGMTSAGTDINECALDPDIC---PNGICENLRGTYKCICNSGYEVDITGKNCVDIN 769
                       DI+ECA++  IC   P+  C +  G Y C C SGYE      NC +IN
Sbjct: 506 -----------VDIDECAVNASICQTNPHETCRDFDGGYSCDCVSGYERPSPSDNCTNIN 652

Query: 770 ECVLNSLLCDNGQ---CRNTPGSFVCTCPKGFVYKPDLKTCEDIDECESSPCINGV---- 822
           EC+  SL   N     C ++ GSF C C  GF       +C D+DEC + P +N      
Sbjct: 653 ECLYASLNTCNMTTEICVDSDGSFGCECKSGF--NSTSGSCTDVDEC-TDPALNTCSDRE 823

Query: 823 -CKNSPGSFICECSPESTL 840
            C NS GS+ C+C     L
Sbjct: 824 DCVNSVGSYTCQCKSTYVL 880

 Score = 85.9 bits (211), Expect = 2e-16,   Method: Compositional matrix adjust.
 Identities = 97/305 (31%), Positives = 135/305 (44%), Gaps = 26/305 (8%)
 Frame = +2

Query: 1243 ECEDNPNICDGGQCTNIPGEYRCLCYDGFMASEDMKTCVDVNECDLNP--------NICL 1294
            EC +NP  C  G C N  G + C C  G    +D  TC    E             N   
Sbjct: 2    ECTNNP--CVNGNCANTDGGFTCSCSSGTFLLQDGITCQVCPEGKFGAGCSSVCTCNATN 175

Query: 1295 SGTCENTKGSFICHCDMGYSGKKGKTGCTDINECEIGAHNCG-RHAVCTNTAGSFKCSCS 1353
            + TC+   G   C+C  G++G    T   DINECE  A      ++ C NT G + C+C 
Sbjct: 176  TDTCDAVTG--FCNCTTGWNGTDCAT---DINECEDSATCASISNSHCNNTLGGYVCACD 340

Query: 1354 PGWIGDGIKCTDLDECSNGTH---MC----SQHADCKNTMGSYRCLCKDGYTGDGFTCTD 1406
             G+   G  C   D+   GT    +C    +   DC + +G+  C C   + G+  T  D
Sbjct: 341  DGFSSSGGMCMPCDDTHYGTQCLQLCPCVRANTQDCDDLIGT--CTCTAFWEGENCT-VD 511

Query: 1407 LDECSEXXXXXXXXXXXXA---PGGYRCECDMGFVPSADGKACEDIDECSLP--NICVFG 1461
            +DEC+                  GGY C+C  G+   +    C +I+EC     N C   
Sbjct: 512  IDECAVNASICQTNPHETCRDFDGGYSCDCVSGYERPSPSDNCTNINECLYASLNTCNMT 691

Query: 1462 T--CHNLPGLFRCECEIGYELDRSGGNCTDVNECLDPT--TCIS-GNCVNTPGSYTCDCP 1516
            T  C +  G F CEC+ G+  + + G+CTDV+EC DP   TC    +CVN+ GSYTC C 
Sbjct: 692  TEICVDSDGSFGCECKSGF--NSTSGSCTDVDECTDPALNTCSDREDCVNSVGSYTCQCK 865

Query: 1517 PDFEL 1521
              + L
Sbjct: 866  STYVL 880

 Score = 82.0 bits (201), Expect = 3e-15,   Method: Compositional matrix adjust.
 Identities = 106/346 (30%), Positives = 144/346 (41%), Gaps = 22/346 (6%)
 Frame = +2

Query: 1033 ECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQCVNTP 1092
            EC   P  C +G C NT G F C C SG  L  +   C    E +          C  T 
Sbjct: 2    ECTNNP--CVNGNCANTDGGFTCSCSSGTFLLQDGITCQVCPEGKFGAGCSSVCTCNATN 175

Query: 1093 GDFECKCDEGY---ESGFMMMKNCMDIDECQRDPLLC---RGGICHNTEGSYRCECPPGH 1146
             D  C    G+    +G+       DI+EC+ D   C       C+NT G Y C C  G 
Sbjct: 176  TD-TCDAVTGFCNCTTGWNGTDCATDINECE-DSATCASISNSHCNNTLGGYVCACDDGF 349

Query: 1147 QLSPNI-SACIDINECELSANLCPHGR-----CVNLIGKYQCACNPGYHPTHDRLFCVDI 1200
              S  +   C D +       LCP  R     C +LIG   C C   +   +     VDI
Sbjct: 350  SSSGGMCMPCDDTHYGTQCLQLCPCVRANTQDCDDLIGT--CTCTAFWEGENCT---VDI 514

Query: 1201 DECSIMNGGCET----FCTNSDGSYECSCQPGFALMPDQRSCTDIDEC-EDNPNICDGGQ 1255
            DEC++    C+T     C + DG Y C C  G+       +CT+I+EC   + N C+   
Sbjct: 515  DECAVNASICQTNPHETCRDFDGGYSCDCVSGYERPSPSDNCTNINECLYASLNTCNMTT 694

Query: 1256 --CTNIPGEYRCLCYDGFMASEDMKTCVDVNEC-DLNPNICLS-GTCENTKGSFICHCDM 1311
              C +  G + C C  GF ++    +C DV+EC D   N C     C N+ GS+ C C  
Sbjct: 695  EICVDSDGSFGCECKSGFNSTS--GSCTDVDECTDPALNTCSDREDCVNSVGSYTCQCKS 868

Query: 1312 GYSGKKGKTGCTDINEC-EIGAHNCGRHAVCTNTAGSFKCSCSPGW 1356
             Y        CTD NEC +   +NC     C +  G ++C C  G+
Sbjct: 869  TYVLVNXV--CTDFNECSDSSLNNCTSKENCVDIIGGYRCDCKTGY 1000

 Score = 80.5 bits (197), Expect = 1e-14,   Method: Compositional matrix adjust.
 Identities = 110/389 (28%), Positives = 153/389 (39%), Gaps = 45/389 (11%)
 Frame = +2

Query: 1942 NLCRNGQCVNTVGSFQCRCNEGYEVAPDGRTCVDINECVLDPGKCAPGTCQ--NLDG--- 1996
            N C NG C NT G F C C+ G  +  DG TC    E     G  +  TC   N D    
Sbjct: 14   NPCVNGNCANTDGGFTCSCSSGTFLLQDGITCQVCPEGKFGAGCSSVCTCNATNTDTCDA 193

Query: 1997 -SYRCICPPGYSLQNDKCEDIDECVEEPEICAL---GTCSNTEGSFKCLCPEGFSLS--- 2049
             +  C C  G++   D   DI+EC E+   CA      C+NT G + C C +GFS S   
Sbjct: 194  VTGFCNCTTGWN-GTDCATDINEC-EDSATCASISNSHCNNTLGGYVCACDDGFSSSGGM 367

Query: 2050 ---------------------STGRRCQDLRMS-YCYAKFEGGKCSSPKSRNHSKQECCC 2087
                                 +  + C DL  +  C A +EG  C+             C
Sbjct: 368  CMPCDDTHYGTQCLQLCPCVRANTQDCDDLIGTCTCTAFWEGENCTVDIDE--------C 523

Query: 2088 ALKGEGWGDPCELCPTEPDEAFRQI-----CPFGSGIIV-GPDDSAVDMDEC--KEPDVC 2139
            A+          +C T P E  R       C   SG     P D+  +++EC     + C
Sbjct: 524  AVNA-------SICQTNPHETCRDFDGGYSCDCVSGYERPSPSDNCTNINECLYASLNTC 682

Query: 2140 RHGQ--CINTDGSYRCECPFGYILEGNECVDTDECSVGNPCGNGTCKNVIXXXXXXXXXX 2197
                  C+++DGS+ CEC  G+      C D DEC+  +P                    
Sbjct: 683  NMTTEICVDSDGSFGCECKSGFNSTSGSCTDVDECT--DP-------------------- 796

Query: 2198 XXXXXMMTCEDINECAQNPLLCAFRCVNTYGSYECKCPVGYVLREDRRMCKDEDECAEGK 2257
                 + TC D  +           CVN+ GSY C+C   YVL     +C D +EC++  
Sbjct: 797  ----ALNTCSDRED-----------CVNSVGSYTCQCKSTYVLV--NXVCTDFNECSDSS 925

Query: 2258 -HDCTEKQMECKNLIGTYMCICGPGYQRR 2285
             ++CT K+  C ++IG Y C C  GY R 
Sbjct: 926  LNNCTSKE-NCVDIIGGYRCDCKTGYARN 1009

 Score = 77.8 bits (190), Expect = 5e-14,   Method: Compositional matrix adjust.
 Identities = 109/383 (28%), Positives = 157/383 (40%), Gaps = 29/383 (7%)
 Frame = +2

Query: 2296 ECQTKPGICENGRCLNTLGSYTCECNDGFTASPTQDECLDNREGYCFSEVLQNMCQIGSS 2355
            EC   P  C NG C NT G +TC C+ G         C    EG  F     ++C   ++
Sbjct: 2    ECTNNP--CVNGNCANTDGGFTCSCSSGTFLLQDGITCQVCPEGK-FGAGCSSVCTCNAT 172

Query: 2356 NRNPVTKSECCCDGGRGW-GPHCEICPFEGTVAYKKLCPHGRGFMTNGADIDECK--VIH 2412
            N +        C+   GW G  C                          DI+EC+     
Sbjct: 173  NTDTCDAVTGFCNCTTGWNGTDC------------------------ATDINECEDSATC 280

Query: 2413 DVCRNGECVNDRGSYHCICKTGYTP--------DIT--GTACVDLNECNQAPKPCNFICK 2462
                N  C N  G Y C C  G++         D T  GT C+ L  C +A       C 
Sbjct: 281  ASISNSHCNNTLGGYVCACDDGFSSSGGMCMPCDDTHYGTQCLQLCPCVRANTQ---DCD 451

Query: 2463 NTEGSYQCSCPKGYILQEDGRSCK-DLDECATKQHNCQF----LCVNTIGGFTCKCPPGF 2517
            +  G+  C+C   +    +G +C  D+DECA     CQ      C +  GG++C C  G+
Sbjct: 452  DLIGT--CTCTAFW----EGENCTVDIDECAVNASICQTNPHETCRDFDGGYSCDCVSGY 613

Query: 2518 TQHHTA--CIDNNECT-SDINLCG-SKGVCQNTPGSFTCECQRGFSLDQSGASCEDVDEC 2573
             +   +  C + NEC  + +N C  +  +C ++ GSF CEC+ GF  + +  SC DVDEC
Sbjct: 614  ERPSPSDNCTNINECLYASLNTCNMTTEICVDSDGSFGCECKSGF--NSTSGSCTDVDEC 787

Query: 2574 E--GNHRC--QHGCQNIIGGYRCSCPQGYLQHYQWNQCVDENECLSAHVCGGAS---CHN 2626
                 + C  +  C N +G Y C C   Y+       C D NEC  + +    S   C +
Sbjct: 788  TDPALNTCSDREDCVNSVGSYTCQCKSTYVLVNX--VCTDFNECSDSSLNNCTSKENCVD 961

Query: 2627 TLGSYKCMCPTGFQYEQFSGGCQ 2649
             +G Y+C C TG+     +G C 
Sbjct: 962  IIGGYRCDCKTGYARNTTTGLCS 1030

 Score = 75.5 bits (184), Expect = 3e-13,   Method: Compositional matrix adjust.
 Identities = 107/387 (27%), Positives = 163/387 (42%), Gaps = 23/387 (5%)
 Frame = +2

Query: 1285 ECDLNPNICLSGTCENTKGSFICHCDMGYSGKKGKTGCTDINECEIGAHNCGRHAVCTNT 1344
            EC  NP  C++G C NT G F C C  G    +    C    E + GA   G  +VCT  
Sbjct: 2    ECTNNP--CVNGNCANTDGGFTCSCSSGTFLLQDGITCQVCPEGKFGA---GCSSVCTCN 166

Query: 1345 AGSFK--------CSCSPGWIGDGIKCTDLDECSNGTHMCS-QHADCKNTMGSYRCLCKD 1395
            A +          C+C+ GW G     TD++EC +     S  ++ C NT+G Y C C D
Sbjct: 167  ATNTDTCDAVTGFCNCTTGWNGTDCA-TDINECEDSATCASISNSHCNNTLGGYVCACDD 343

Query: 1396 GYTGDGFTCTDLDECSEXXXXXXXXXXXXAPGGYRCECDMGF---VPSADGKACE-DIDE 1451
            G++  G  C   D+ +                   C+  +G        +G+ C  DIDE
Sbjct: 344  GFSSSGGMCMPCDD-THYGTQCLQLCPCVRANTQDCDDLIGTCTCTAFWEGENCTVDIDE 520

Query: 1452 CSL-PNICVFG---TCHNLPGLFRCECEIGYELDRSGGNCTDVNECLDPT--TC--ISGN 1503
            C++  +IC      TC +  G + C+C  GYE      NCT++NECL  +  TC   +  
Sbjct: 521  CAVNASICQTNPHETCRDFDGGYSCDCVSGYERPSPSDNCTNINECLYASLNTCNMTTEI 700

Query: 1504 CVNTPGSYTCDCPPDFELNPTRVGCVDTRSGNCYLDIRPRGDNGDTACSNEIGVGVSKAS 1563
            CV++ GS+ C+C   F          ++ SG+C  D+    D     CS+       +  
Sbjct: 701  CVDSDGSFGCECKSGF----------NSTSGSC-TDVDECTDPALNTCSD-------RED 826

Query: 1564 CCCSLGKAWGTPCELCPSVNTSEYKILCPGGEGFRPNPITVILEDIDECQE--LPGLCQG 1621
            C  S+G ++   C+       S Y +            +  +  D +EC +  L      
Sbjct: 827  CVNSVG-SYTCQCK-------STYVL------------VNXVCTDFNECSDSSLNNCTSK 946

Query: 1622 GKCINTFGSFQCRCPTGYYLNEDTRVC 1648
              C++  G ++C C TGY  N  T +C
Sbjct: 947  ENCVDIIGGYRCDCKTGYARNTTTGLC 1027

 Score = 74.7 bits (182), Expect = 5e-13,   Method: Compositional matrix adjust.
 Identities = 98/358 (27%), Positives = 135/358 (37%), Gaps = 77/358 (21%)
 Frame = +2

Query: 1611 ECQELPGLCQGGKCINTFGSFQCRCPTGYYLNED-------------------------- 1644
            EC   P  C  G C NT G F C C +G +L +D                          
Sbjct: 2    ECTNNP--CVNGNCANTDGGFTCSCSSGTFLLQDGITCQVCPEGKFGAGCSSVCTCNATN 175

Query: 1645 TRVCD-------------------DVNECETPGICGP---GTCYNTVGNYTCICPPDYMQ 1682
            T  CD                   D+NECE    C       C NT+G Y C C   +  
Sbjct: 176  TDTCDAVTGFCNCTTGWNGTDCATDINECEDSATCASISNSHCNNTLGGYVCACDDGFSS 355

Query: 1683 VNG----------GNNCMDMRRSLCYRNYYADNQTCDGELLFNMTKKMCCCSYNIGRAWN 1732
              G          G  C+ +    C R   A+ Q CD +L+   T    C ++  G    
Sbjct: 356  SGGMCMPCDDTHYGTQCLQL--CPCVR---ANTQDCD-DLIGTCT----CTAFWEGENCT 505

Query: 1733 KPCEQCPIPS----TDEFATLCGSQRPGFVIDIYTGL--PVDIDECREIP-------GVC 1779
               ++C + +    T+   T C     G+  D  +G   P   D C  I          C
Sbjct: 506  VDIDECAVNASICQTNPHET-CRDFDGGYSCDCVSGYERPSPSDNCTNINECLYASLNTC 682

Query: 1780 E--NGVCINMVGSFRCECPVGFFYNDKLLVCEDIDECQNGPV--CQRNAECINTAGSYRC 1835
                 +C++  GSF CEC  GF  N     C D+DEC +  +  C    +C+N+ GSY C
Sbjct: 683  NMTTEICVDSDGSFGCECKSGF--NSTSGSCTDVDECTDPALNTCSDREDCVNSVGSYTC 856

Query: 1836 DCKPGYRLTSTGQCNDRNECQE--IPNICSHGQCIDTVGSFYCLCHTGFKTNVDQTMC 1891
             CK  Y L +   C D NEC +  + N  S   C+D +G + C C TG+  N    +C
Sbjct: 857  QCKSTYVLVNX-VCTDFNECSDSSLNNCTSKENCVDIIGGYRCDCKTGYARNTTTGLC 1027

 Score = 68.2 bits (165), Expect = 5e-11,   Method: Compositional matrix adjust.
 Identities = 86/296 (29%), Positives = 113/296 (38%), Gaps = 67/296 (22%)
 Frame = +2

Query: 2455 KPC-NFICKNTEGSYQCSCPKGYILQEDGRSCKDLDECATKQHNCQFLCV-NTIGGFTCK 2512
             PC N  C NT+G + CSC  G  L +DG +C+   E       C  +C  N     TC 
Sbjct: 14   NPCVNGNCANTDGGFTCSCSSGTFLLQDGITCQVCPE-GKFGAGCSSVCTCNATNTDTCD 190

Query: 2513 CPPGFTQHHTACIDNNECTSDINLCG--------SKGVCQNTPGSFTCECQRGFSLDQSG 2564
               GF    T   +  +C +DIN C         S   C NT G + C C  GFS   SG
Sbjct: 191  AVTGFCNCTTG-WNGTDCATDINECEDSATCASISNSHCNNTLGGYVCACDDGFS--SSG 361

Query: 2565 ASCE---------------------------------------------DVDECEGNHR- 2578
              C                                              D+DEC  N   
Sbjct: 362  GMCMPCDDTHYGTQCLQLCPCVRANTQDCDDLIGTCTCTAFWEGENCTVDIDECAVNASI 541

Query: 2579 CQ----HGCQNIIGGYRCSCPQGYLQHYQWNQCVDENECL--SAHVCGGAS--CHNTLGS 2630
            CQ      C++  GGY C C  GY +    + C + NECL  S + C   +  C ++ GS
Sbjct: 542  CQTNPHETCRDFDGGYSCDCVSGYERPSPSDNCTNINECLYASLNTCNMTTEICVDSDGS 721

Query: 2631 YKCMCPTGFQYEQFSGGCQDINECGS-SQAPCS--YGCSNTEGGYLCGCPPGYFRI 2683
            + C C +GF     SG C D++EC   +   CS    C N+ G Y C C   Y  +
Sbjct: 722  FGCECKSGFN--STSGSCTDVDECTDPALNTCSDREDCVNSVGSYTCQCKSTYVLV 883

 Score = 62.8 bits (151), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 108/420 (25%), Positives = 154/420 (36%), Gaps = 26/420 (6%)
 Frame = +2

Query: 1456 NICVFGTCHNLPGLFRCECEIGYEL------------DRSGGNCTDVNEC----LDPTTC 1499
            N CV G C N  G F C C  G  L             + G  C+ V  C     D    
Sbjct: 14   NPCVNGNCANTDGGFTCSCSSGTFLLQDGITCQVCPEGKFGAGCSSVCTCNATNTDTCDA 193

Query: 1500 ISGNCVNTPGSYTCDCPPDFELNPTRVGCVDTRSGNCYLDIRPRGDNGDTACSNEIGVGV 1559
            ++G C  T G    DC  D         C    + +C   +      G   C+ + G   
Sbjct: 194  VTGFCNCTTGWNGTDCATDINECEDSATCASISNSHCNNTL------GGYVCACDDGFSS 355

Query: 1560 SKASCCCSLGKAWGTPC-ELCPSVNTSEYKILCPGGEGFRPNPITVILEDIDECQELPGL 1618
            S   C       +GT C +LCP V               R N          +C +L G 
Sbjct: 356  SGGMCMPCDDTHYGTQCLQLCPCV---------------RAN--------TQDCDDLIGT 466

Query: 1619 CQGGKCINTFGSFQCRCPTGYYLNEDTRVCDDVNECET-PGICGPG---TCYNTVGNYTC 1674
            C                 T ++  E+  V  D++EC     IC      TC +  G Y+C
Sbjct: 467  CT---------------CTAFWEGENCTV--DIDECAVNASICQTNPHETCRDFDGGYSC 595

Query: 1675 ICPPDYMQVNGGNNCMDMRRSLCYRNYYADNQTCDGELLFNMTKKMCCCSYNIGRAWNKP 1734
             C   Y + +  +NC ++   L     YA   TC      NMT ++C             
Sbjct: 596  DCVSGYERPSPSDNCTNINECL-----YASLNTC------NMTTEIC------------- 703

Query: 1735 CEQCPIPSTDEFATLCGSQRPGFVIDIYTGLPVDIDECRE--IPGVCENGVCINMVGSFR 1792
                 + S   F   C   + GF  +  +G   D+DEC +  +    +   C+N VGS+ 
Sbjct: 704  -----VDSDGSFGCEC---KSGF--NSTSGSCTDVDECTDPALNTCSDREDCVNSVGSYT 853

Query: 1793 CECPVGFFYNDKLLVCEDIDECQNGPV--CQRNAECINTAGSYRCDCKPGY-RLTSTGQC 1849
            C+C   +   +   VC D +EC +  +  C     C++  G YRCDCK GY R T+TG C
Sbjct: 854  CQCKSTYVLVNX--VCTDFNECSDSSLNNCTSKENCVDIIGGYRCDCKTGYARNTTTGLC 1027

 Score = 60.8 bits (146), Expect = 8e-09,   Method: Compositional matrix adjust.
 Identities = 95/389 (24%), Positives = 136/389 (34%), Gaps = 61/389 (15%)
 Frame = +2

Query: 625 CMNGRCVNTDGSYRCECFPGLAVGLDGRVCVDTHMRSTCYGGYRRGQCVKPLFGAVTKSE 684
           C+NG C NTDG + C C  G  +  DG  C                 C +  FGA   S 
Sbjct: 20  CVNGNCANTDGGFTCSCSSGTFLLQDGITCQ---------------VCPEGKFGAGCSSV 154

Query: 685 CCCASTEYAFGEPCQPCPAQNSAEYQAL-----CSSGPGMTSAGTDINECALDPDICP-- 737
           C               C A N+    A+     C++G   T   TDINEC  D   C   
Sbjct: 155 C--------------TCNATNTDTCDAVTGFCNCTTGWNGTDCATDINECE-DSATCASI 289

Query: 738 -NGICENLRGTYKCICNSGYEVD------------------------------------- 759
            N  C N  G Y C C+ G+                                        
Sbjct: 290 SNSHCNNTLGGYVCACDDGFSSSGGMCMPCDDTHYGTQCLQLCPCVRANTQDCDDLIGTC 469

Query: 760 -----ITGKNC-VDINECVLNSLLCDNG---QCRNTPGSFVCTCPKGFVYKPDLKTCEDI 810
                  G+NC VDI+EC +N+ +C       CR+  G + C C  G+        C +I
Sbjct: 470 TCTAFWEGENCTVDIDECAVNASICQTNPHETCRDFDGGYSCDCVSGYERPSPSDNCTNI 649

Query: 811 DECESSPC-----INGVCKNSPGSFICECSPESTLDPTKTICIETIKGTCWQTVIDGRCE 865
           +EC  +          +C +S GSF CEC               +  G+C  T +D   +
Sbjct: 650 NECLYASLNTCNMTTEICVDSDGSFGCECKSG----------FNSTSGSC--TDVDECTD 793

Query: 866 ININGATLKSECCSSLGAAWGSPCTICQLDPICGKGFSRIKGTQCEDINECE--VFPGVC 923
             +N  + + +C +S+G+        CQ      K    +    C D NEC         
Sbjct: 794 PALNTCSDREDCVNSVGSY------TCQC-----KSTYVLVNXVCTDFNECSDSSLNNCT 940

Query: 924 KNGLCVNSRGSFKCECPNGMTLDATGRIC 952
               CV+  G ++C+C  G   + T  +C
Sbjct: 941 SKENCVDIIGGYRCDCKTGYARNTTTGLC 1027

 Score = 47.4 bits (111), Expect = 9e-05,   Method: Compositional matrix adjust.
 Identities = 72/298 (24%), Positives = 100/298 (33%), Gaps = 103/298 (34%)
 Frame = +2

Query: 462 CQNGRCIPTPGSYRCECNKGFQL----------------------------------DIR 487
           C NG C  T G + C C+ G  L                                   + 
Sbjct: 20  CVNGNCANTDGGFTCSCSSGTFLLQDGITCQVCPEGKFGAGCSSVCTCNATNTDTCDAVT 199

Query: 488 GEC------------IDVDECEKNP----CTGGECINNQGSYTCHCRAGYQST------- 524
           G C             D++ECE +      +   C N  G Y C C  G+ S+       
Sbjct: 200 GFCNCTTGWNGTDCATDINECEDSATCASISNSHCNNTLGGYVCACDDGFSSSGGMCMPC 379

Query: 525 --------------LTRTECRDIDE----------------------CLQNGRICNNG-- 546
                           R   +D D+                      C  N  IC     
Sbjct: 380 DDTHYGTQCLQLCPCVRANTQDCDDLIGTCTCTAFWEGENCTVDIDECAVNASICQTNPH 559

Query: 547 -RCINTDGSFHCVCNAGFHVTRDGKNCEDMDEC--SIRNMC--LNGMCINEDGSFKCICK 601
             C + DG + C C +G+       NC +++EC  +  N C     +C++ DGSF C CK
Sbjct: 560 ETCRDFDGGYSCDCVSGYERPSPSDNCTNINECLYASLNTCNMTTEICVDSDGSFGCECK 739

Query: 602 PGFQLASDGRYCKDINECETPGI--CMNGR-CVNTDGSYRCECFPGLAVGLDGRVCVD 656
            GF   S    C D++EC  P +  C +   CVN+ GSY C+C       L   VC D
Sbjct: 740 SGFNSTSGS--CTDVDECTDPALNTCSDREDCVNSVGSYTCQCKSTYV--LVNXVCTD 901

 Score = 40.8 bits (94), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 23/60 (38%), Positives = 35/60 (58%), Gaps = 2/60 (3%)
 Frame = +2

Query: 262 CINTVGSFECKCPAGHKFNEVSQKCEDIDECS--TIPGVCDGGECTNTVSSYFCKCPPGF 319
           C+++ GSF C+C +G  FN  S  C D+DEC+   +    D  +C N+V SY C+C   +
Sbjct: 701 CVDSDGSFGCECKSG--FNSTSGSCTDVDECTDPALNTCSDREDCVNSVGSYTCQCKSTY 874

 Score = 37.0 bits (84), Expect = 0.10,   Method: Compositional matrix adjust.
 Identities = 60/230 (26%), Positives = 86/230 (37%), Gaps = 33/230 (14%)
 Frame = +2

Query: 135 LCQKGYIGTHCGQPVCESGCLNGGRCVA-PNRCACTYGFTGPQCERDYR----TGPCFTV 189
           +C +G  G  C   VC     N   C A    C CT G+ G  C  D      +  C ++
Sbjct: 113 VCPEGKFGAGC-SSVCTCNATNTDTCDAVTGFCNCTTGWNGTDCATDINECEDSATCASI 289

Query: 190 VSNQMCQGQLSGIVC--------TKTLCCATVGRAWGHPCEMCPAQPHPCRRGFIPN--- 238
            SN  C   L G VC        +  +C       +G  C     Q  PC R    +   
Sbjct: 290 -SNSHCNNTLGGYVCACDDGFSSSGGMCMPCDDTHYGTQC----LQLCPCVRANTQDCDD 454

Query: 239 -IRTGACQ----------DVDECQAIPGMCQGG---NCINTVGSFECKCPAGHKFNEVSQ 284
            I T  C           D+DEC     +CQ      C +  G + C C +G++    S 
Sbjct: 455 LIGTCTCTAFWEGENCTVDIDECAVNASICQTNPHETCRDFDGGYSCDCVSGYERPSPSD 634

Query: 285 KCEDIDECSTIP-GVCDGGE--CTNTVSSYFCKCPPGFYTSPDGTRCVDV 331
            C +I+EC       C+     C ++  S+ C+C  GF ++     C DV
Sbjct: 635 NCTNINECLYASLNTCNMTTEICVDSDGSFGCECKSGFNSTSG--SCTDV 778
>28816
          Length = 437

 Score = 83.2 bits (204), Expect(2) = 2e-20,   Method: Compositional matrix adjust.
 Identities = 50/110 (45%), Positives = 63/110 (57%), Gaps = 2/110 (1%)
 Frame = +3

Query: 1130 ICHNTEGSYRCECP-PGHQLSPNISACIDINECELSANLCPHGRCVNLIGKYQCACNPGY 1188
            +C NT GSY C C  P + L+ N  +C D++ECE     C H RCVN  G   C C  GY
Sbjct: 15   LCINTPGSYNCNCTHPLYTLNRNGYSCDDVDECETGQLRCTH-RCVNTAGGAHCTCPRGY 191

Query: 1189 HPTHDRLFCVDIDECSIMNGGCETFCTNSDGSYECSC-QPGFALMPDQRS 1237
                D   C D +EC+  NGGCE  CTN++GS+EC C +PGF L   + S
Sbjct: 192  QLADDNTTCQDTNECTNSNGGCEDVCTNTEGSFECECTKPGFRLSQTRGS 341

 Score = 36.6 bits (83), Expect(2) = 2e-20,   Method: Compositional matrix adjust.
 Identities = 19/41 (46%), Positives = 25/41 (60%)
 Frame = +2

Query: 1271 FMASEDMKTCVDVNECDLNPNICLSGTCENTKGSFICHCDM 1311
                 D + CVD+NEC LN ++C  G CEN  GS+ CHC +
Sbjct: 314  LQTQPDKRQCVDINEC-LNKSLC-EGRCENLYGSYRCHCTV 430

 Score = 83.2 bits (204), Expect(2) = 3e-19,   Method: Compositional matrix adjust.
 Identities = 54/114 (47%), Positives = 65/114 (57%), Gaps = 4/114 (3%)
 Frame = +3

Query: 2457 CNFICKNTEGSYQCSCPKG-YILQEDGRSCKDLDECATKQHNCQFLCVNTIGGFTCKCPP 2515
            C+ +C NT GSY C+C    Y L  +G SC D+DEC T Q  C   CVNT GG  C CP 
Sbjct: 6    CHQLCINTPGSYNCNCTHPLYTLNRNGYSCDDVDECETGQLRCTHRCVNTAGGAHCTCPR 185

Query: 2516 GF--TQHHTACIDNNECTSDINLCGSKGVCQNTPGSFTCECQR-GFSLDQSGAS 2566
            G+     +T C D NECT+     G + VC NT GSF CEC + GF L Q+  S
Sbjct: 186  GYQLADDNTTCQDTNECTNSNG--GCEDVCTNTEGSFECECTKPGFRLSQTRGS 341

 Score = 33.1 bits (74), Expect(2) = 3e-19,   Method: Compositional matrix adjust.
 Identities = 17/32 (53%), Positives = 20/32 (62%)
 Frame = +2

Query: 2606 QCVDENECLSAHVCGGASCHNTLGSYKCMCPT 2637
            QCVD NECL+  +C G  C N  GSY+C C  
Sbjct: 338  QCVDINECLNKSLCEG-RCENLYGSYRCHCTV 430

 Score = 69.3 bits (168), Expect(2) = 2e-16,   Method: Compositional matrix adjust.
 Identities = 44/105 (41%), Positives = 60/105 (57%), Gaps = 3/105 (2%)
 Frame = +3

Query: 506 CINNQGSYTCHCRAGYQSTLTRT--ECRDIDECLQNGRICNNGRCINTDGSFHCVCNAGF 563
           CIN  GSY C+C      TL R    C D+DEC + G++    RC+NT G  HC C  G+
Sbjct: 18  CINTPGSYNCNCTHPLY-TLNRNGYSCDDVDEC-ETGQLRCTHRCVNTAGGAHCTCPRGY 191

Query: 564 HVTRDGKNCEDMDECSIRNMCLNGMCINEDGSFKCIC-KPGFQLA 607
            +  D   C+D +EC+  N     +C N +GSF+C C KPGF+L+
Sbjct: 192 QLADDNTTCQDTNECTNSNGGCEDVCTNTEGSFECECTKPGFRLS 326

 Score = 37.4 bits (85), Expect(2) = 2e-16,   Method: Compositional matrix adjust.
 Identities = 20/38 (52%), Positives = 21/38 (55%)
 Frame = +2

Query: 604 FQLASDGRYCKDINECETPGICMNGRCVNTDGSYRCEC 641
            Q   D R C DINEC    +C  GRC N  GSYRC C
Sbjct: 314 LQTQPDKRQCVDINECLNKSLC-EGRCENLYGSYRCHC 424

 Score = 75.9 bits (185), Expect(2) = 4e-14,   Method: Compositional matrix adjust.
 Identities = 47/108 (43%), Positives = 63/108 (58%), Gaps = 3/108 (2%)
 Frame = +3

Query: 2542 VCQNTPGSFTCECQRG-FSLDQSGASCEDVDECE-GNHRCQHGCQNIIGGYRCSCPQGYL 2599
            +C NTPGS+ C C    ++L+++G SC+DVDECE G  RC H C N  GG  C+CP+GY 
Sbjct: 15   LCINTPGSYNCNCTHPLYTLNRNGYSCDDVDECETGQLRCTHRCVNTAGGAHCTCPRGYQ 194

Query: 2600 QHYQWNQCVDENECLSAHVCGGASCHNTLGSYKCMCPT-GFQYEQFSG 2646
                   C D NEC +++      C NT GS++C C   GF+  Q  G
Sbjct: 195  LADDNTTCQDTNECTNSNGGCEDVCTNTEGSFECECTKPGFRLSQTRG 338

 Score = 22.7 bits (47), Expect(2) = 4e-14,   Method: Compositional matrix adjust.
 Identities = 13/30 (43%), Positives = 16/30 (53%)
 Frame = +2

Query: 2648 CQDINECGSSQAPCSYGCSNTEGGYLCGCP 2677
            C DINEC  +++ C   C N  G Y C C 
Sbjct: 341  CVDINEC-LNKSLCEGRCENLYGSYRCHCT 427

 Score = 73.6 bits (179), Expect(2) = 8e-14,   Method: Compositional matrix adjust.
 Identities = 42/105 (40%), Positives = 57/105 (54%), Gaps = 2/105 (1%)
 Frame = +3

Query: 2420 CVNDRGSYHCICKTG-YTPDITGTACVDLNECNQAPKPCNFICKNTEGSYQCSCPKGYIL 2478
            C+N  GSY+C C    YT +  G +C D++EC      C   C NT G   C+CP+GY L
Sbjct: 18   CINTPGSYNCNCTHPLYTLNRNGYSCDDVDECETGQLRCTHRCVNTAGGAHCTCPRGYQL 197

Query: 2479 QEDGRSCKDLDECATKQHNCQFLCVNTIGGFTCKC-PPGFTQHHT 2522
             +D  +C+D +EC      C+ +C NT G F C+C  PGF    T
Sbjct: 198  ADDNTTCQDTNECTNSNGGCEDVCTNTEGSFECECTKPGFRLSQT 332

 Score = 23.9 bits (50), Expect(2) = 8e-14,   Method: Compositional matrix adjust.
 Identities = 14/31 (45%), Positives = 20/31 (64%)
 Frame = +2

Query: 2524 CIDNNECTSDINLCGSKGVCQNTPGSFTCEC 2554
            C+D NEC +  +LC  +G C+N  GS+ C C
Sbjct: 341  CVDINECLNK-SLC--EGRCENLYGSYRCHC 424

 Score = 68.9 bits (167), Expect(2) = 2e-12,   Method: Compositional matrix adjust.
 Identities = 47/109 (43%), Positives = 56/109 (51%), Gaps = 3/109 (2%)
 Frame = +3

Query: 1907 CRNTIGSFNCRCNHGFILSHNN--DCIDVDECATGNGNLCRNGQCVNTVGSFQCRCNEGY 1964
            C NT GS+NC C H     + N   C DVDEC T  G L    +CVNT G   C C  GY
Sbjct: 18   CINTPGSYNCNCTHPLYTLNRNGYSCDDVDECET--GQLRCTHRCVNTAGGAHCTCPRGY 191

Query: 1965 EVAPDGRTCVDINECVLDPGKCAPGTCQNLDGSYRCIC-PPGYSLQNDK 2012
            ++A D  TC D NEC    G C    C N +GS+ C C  PG+ L   +
Sbjct: 192  QLADDNTTCQDTNECTNSNGGCED-VCTNTEGSFECECTKPGFRLSQTR 335

 Score = 23.9 bits (50), Expect(2) = 2e-12,   Method: Compositional matrix adjust.
 Identities = 13/32 (40%), Positives = 20/32 (62%)
 Frame = +2

Query: 2012 KCEDIDECVEEPEICALGTCSNTEGSFKCLCP 2043
            +C DI+EC+ +  +C  G C N  GS++C C 
Sbjct: 338  QCVDINECLNKS-LCE-GRCENLYGSYRCHCT 427

 Score = 55.5 bits (132), Expect(2) = 3e-12,   Method: Compositional matrix adjust.
 Identities = 42/109 (38%), Positives = 53/109 (48%), Gaps = 2/109 (1%)
 Frame = +3

Query: 1043 HGKCRNTIGSFKCRCDSG-FALDSEERNCTDIDECRISPDLCGRGQCVNTPGDFECKCDE 1101
            H  C NT GS+ C C    + L+    +C D+DEC      C   +CVNT G   C C  
Sbjct: 9    HQLCINTPGSYNCNCTHPLYTLNRNGYSCDDVDECETGQLRCTH-RCVNTAGGAHCTCPR 185

Query: 1102 GYESGFMMMKNCMDIDECQRDPLLCRGGICHNTEGSYRCEC-PPGHQLS 1149
            GY+        C D +EC      C   +C NTEGS+ CEC  PG +LS
Sbjct: 186  GYQLADDNTT-CQDTNECTNSNGGCE-DVCTNTEGSFECECTKPGFRLS 326

 Score = 36.6 bits (83), Expect(2) = 3e-12,   Method: Compositional matrix adjust.
 Identities = 20/38 (52%), Positives = 25/38 (65%)
 Frame = +2

Query: 1147 QLSPNISACIDINECELSANLCPHGRCVNLIGKYQCAC 1184
            Q  P+   C+DINEC L+ +LC  GRC NL G Y+C C
Sbjct: 317  QTQPDKRQCVDINEC-LNKSLC-EGRCENLYGSYRCHC 424

 Score = 56.6 bits (135), Expect(2) = 5e-12,   Method: Compositional matrix adjust.
 Identities = 31/81 (38%), Positives = 43/81 (53%), Gaps = 1/81 (1%)
 Frame = +3

Query: 2204 MTCEDINECAQNPLLCAFRCVNTYGSYECKCPVGYVLREDRRMCKDEDECAEGKHDCTEK 2263
             +C+D++EC    L C  RCVNT G   C CP GY L +D   C+D +EC      C + 
Sbjct: 87   YSCDDVDECETGQLRCTHRCVNTAGGAHCTCPRGYQLADDNTTCQDTNECTNSNGGCEDV 266

Query: 2264 QMECKNLIGTYMCIC-GPGYQ 2283
               C N  G++ C C  PG++
Sbjct: 267  ---CTNTEGSFECECTKPGFR 320

 Score = 34.7 bits (78), Expect(2) = 5e-12,   Method: Compositional matrix adjust.
 Identities = 20/38 (52%), Positives = 23/38 (60%)
 Frame = +2

Query: 2283 QRRPDGEGCIDENECQTKPGICENGRCLNTLGSYTCEC 2320
            Q +PD   C+D NEC  K  +CE GRC N  GSY C C
Sbjct: 317  QTQPDKRQCVDINECLNK-SLCE-GRCENLYGSYRCHC 424

 Score = 69.7 bits (169), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 40/102 (39%), Positives = 55/102 (53%), Gaps = 2/102 (1%)
 Frame = +3

Query: 548 CINTDGSFHCVCNAGFH-VTRDGKNCEDMDECSIRNMCLNGMCINEDGSFKCICKPGFQL 606
           CINT GS++C C    + + R+G +C+D+DEC    +     C+N  G   C C  G+QL
Sbjct: 18  CINTPGSYNCNCTHPLYTLNRNGYSCDDVDECETGQLRCTHRCVNTAGGAHCTCPRGYQL 197

Query: 607 ASDGRYCKDINECETPGICMNGRCVNTDGSYRCECF-PGLAV 647
           A D   C+D NEC          C NT+GS+ CEC  PG  +
Sbjct: 198 ADDNTTCQDTNECTNSNGGCEDVCTNTEGSFECECTKPGFRL 323

 Score = 49.7 bits (117), Expect(2) = 3e-11,   Method: Compositional matrix adjust.
 Identities = 39/108 (36%), Positives = 55/108 (50%), Gaps = 4/108 (3%)
 Frame = +3

Query: 1864 HGQCIDTVGSFYCLC-HTGFKTNVDQTMCLDINECERDACG-NGTCRNTIGSFNCRCNHG 1921
            H  CI+T GS+ C C H  +  N +   C D++ECE         C NT G  +C C  G
Sbjct: 9    HQLCINTPGSYNCNCTHPLYTLNRNGYSCDDVDECETGQLRCTHRCVNTAGGAHCTCPRG 188

Query: 1922 FILSHNN-DCIDVDECATGNGNLCRNGQCVNTVGSFQCRCNE-GYEVA 1967
            + L+ +N  C D +EC   NG       C NT GSF+C C + G+ ++
Sbjct: 189  YQLADDNTTCQDTNECTNSNGGC--EDVCTNTEGSFECECTKPGFRLS 326

 Score = 38.9 bits (89), Expect(2) = 3e-11,   Method: Compositional matrix adjust.
 Identities = 22/38 (57%), Positives = 25/38 (65%)
 Frame = +2

Query: 1965 EVAPDGRTCVDINECVLDPGKCAPGTCQNLDGSYRCIC 2002
            +  PD R CVDINEC L+   C  G C+NL GSYRC C
Sbjct: 317  QTQPDKRQCVDINEC-LNKSLC-EGRCENLYGSYRCHC 424

 Score = 53.1 bits (126), Expect(2) = 2e-10,   Method: Compositional matrix adjust.
 Identities = 39/104 (37%), Positives = 51/104 (49%), Gaps = 3/104 (2%)
 Frame = +3

Query: 1783 VCINMVGSFRCECPVGFF-YNDKLLVCEDIDECQNGPVCQRNAECINTAGSYRCDCKPGY 1841
            +CIN  GS+ C C    +  N     C+D+DEC+ G + +    C+NTAG   C C  GY
Sbjct: 15   LCINTPGSYNCNCTHPLYTLNRNGYSCDDVDECETGQL-RCTHRCVNTAGGAHCTCPRGY 191

Query: 1842 RLT-STGQCNDRNECQEIPNICSHGQCIDTVGSFYCLCHT-GFK 1883
            +L      C D NEC      C    C +T GSF C C   GF+
Sbjct: 192  QLADDNTTCQDTNECTNSNGGC-EDVCTNTEGSFECECTKPGFR 320

 Score = 33.1 bits (74), Expect(2) = 2e-10,   Method: Compositional matrix adjust.
 Identities = 15/37 (40%), Positives = 20/37 (54%)
 Frame = +2

Query: 1882 FKTNVDQTMCLDINECERDACGNGTCRNTIGSFNCRC 1918
             +T  D+  C+DINEC   +   G C N  GS+ C C
Sbjct: 314  LQTQPDKRQCVDINECLNKSLCEGRCENLYGSYRCHC 424

 Score = 61.2 bits (147), Expect(2) = 3e-10,   Method: Compositional matrix adjust.
 Identities = 41/101 (40%), Positives = 51/101 (50%), Gaps = 1/101 (0%)
 Frame = +3

Query: 1210 CETFCTNSDGSYECSC-QPGFALMPDQRSCTDIDECEDNPNICDGGQCTNIPGEYRCLCY 1268
            C   C N+ GSY C+C  P + L  +  SC D+DECE     C   +C N  G   C C 
Sbjct: 6    CHQLCINTPGSYNCNCTHPLYTLNRNGYSCDDVDECETGQLRCTH-RCVNTAGGAHCTCP 182

Query: 1269 DGFMASEDMKTCVDVNECDLNPNICLSGTCENTKGSFICHC 1309
             G+  ++D  TC D NEC  N N      C NT+GSF C C
Sbjct: 183  RGYQLADDNTTCQDTNEC-TNSNGGCEDVCTNTEGSFECEC 302

 Score = 24.3 bits (51), Expect(2) = 3e-10,   Method: Compositional matrix adjust.
 Identities = 15/35 (42%), Positives = 19/35 (54%)
 Frame = +2

Query: 1319 KTGCTDINECEIGAHNCGRHAVCTNTAGSFKCSCS 1353
            K  C DINEC   +   GR   C N  GS++C C+
Sbjct: 332  KRQCVDINECLNKSLCEGR---CENLYGSYRCHCT 427

 Score = 64.7 bits (156), Expect = 5e-10,   Method: Compositional matrix adjust.
 Identities = 49/115 (42%), Positives = 57/115 (49%), Gaps = 3/115 (2%)
 Frame = +3

Query: 2219 CAFRCVNTYGSYECKC--PVGYVLREDRRMCKDEDECAEGKHDCTEKQMECKNLIGTYMC 2276
            C   C+NT GSY C C  P+ Y L  +   C D DEC  G+  CT +   C N  G   C
Sbjct: 6    CHQLCINTPGSYNCNCTHPL-YTLNRNGYSCDDVDECETGQLRCTHR---CVNTAGGAHC 173

Query: 2277 ICGPGYQRRPDGEGCIDENECQTKPGICENGRCLNTLGSYTCECND-GFTASPTQ 2330
             C  GYQ   D   C D NEC    G CE+  C NT GS+ CEC   GF  S T+
Sbjct: 174  TCPRGYQLADDNTTCQDTNECTNSNGGCED-VCTNTEGSFECECTKPGFRLSQTR 335

 Score = 63.9 bits (154), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 40/109 (36%), Positives = 51/109 (46%), Gaps = 1/109 (0%)
 Frame = +3

Query: 2578 RCQHGCQNIIGGYRCSCPQG-YLQHYQWNQCVDENECLSAHVCGGASCHNTLGSYKCMCP 2636
            RC   C N  G Y C+C    Y  +     C D +EC +  +     C NT G   C CP
Sbjct: 3    RCHQLCINTPGSYNCNCTHPLYTLNRNGYSCDDVDECETGQLRCTHRCVNTAGGAHCTCP 182

Query: 2637 TGFQYEQFSGGCQDINECGSSQAPCSYGCSNTEGGYLCGCPPGYFRIGQ 2685
             G+Q    +  CQD NEC +S   C   C+NTEG + C C    FR+ Q
Sbjct: 183  RGYQLADDNTTCQDTNECTNSNGGCEDVCTNTEGSFECECTKPGFRLSQ 329

 Score = 63.2 bits (152), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 46/117 (39%), Positives = 60/117 (51%), Gaps = 4/117 (3%)
 Frame = +3

Query: 1826 CINTAGSYRCDC-KPGYRLTSTG-QCNDRNECQEIPNICSHGQCIDTVGSFYCLCHTGFK 1883
            CINT GSY C+C  P Y L   G  C+D +EC+     C+H +C++T G  +C C  G++
Sbjct: 18   CINTPGSYNCNCTHPLYTLNRNGYSCDDVDECETGQLRCTH-RCVNTAGGAHCTCPRGYQ 194

Query: 1884 TNVDQTMCLDINECERDACG-NGTCRNTIGSFNCRCNH-GFILSHNNDCIDVDECAT 1938
               D T C D NEC     G    C NT GSF C C   GF LS     + +   A+
Sbjct: 195  LADDNTTCQDTNECTNSNGGCEDVCTNTEGSFECECTKPGFRLSQTRGSV*ISTSAS 365

 Score = 55.5 bits (132), Expect(2) = 4e-09,   Method: Compositional matrix adjust.
 Identities = 44/106 (41%), Positives = 55/106 (51%), Gaps = 5/106 (4%)
 Frame = +3

Query: 467 CIPTPGSYRCECNKG-FQLDIRG-ECIDVDECEKNP--CTGGECINNQGSYTCHCRAGYQ 522
           CI TPGSY C C    + L+  G  C DVDECE     CT   C+N  G   C C  GYQ
Sbjct: 18  CINTPGSYNCNCTHPLYTLNRNGYSCDDVDECETGQLRCT-HRCVNTAGGAHCTCPRGYQ 194

Query: 523 STLTRTECRDIDECLQNGRICNNGRCINTDGSFHCVCNA-GFHVTR 567
                T C+D +EC  +   C +  C NT+GSF C C   GF +++
Sbjct: 195 LADDNTTCQDTNECTNSNGGCED-VCTNTEGSFECECTKPGFRLSQ 329

 Score = 26.2 bits (56), Expect(2) = 4e-09,   Method: Compositional matrix adjust.
 Identities = 14/40 (35%), Positives = 22/40 (55%)
 Frame = +2

Query: 561 AGFHVTRDGKNCEDMDECSIRNMCLNGMCINEDGSFKCIC 600
           A      D + C D++EC  +++C  G C N  GS++C C
Sbjct: 308 ARLQTQPDKRQCVDINECLNKSLC-EGRCENLYGSYRCHC 424

 Score = 62.0 bits (149), Expect = 4e-09,   Method: Compositional matrix adjust.
 Identities = 44/111 (39%), Positives = 61/111 (54%), Gaps = 6/111 (5%)
 Frame = +3

Query: 740 ICENLRGTYKCICNSG-YEVDITGKNCVDINECVLNSLLCDNGQCRNTPGSFVCTCPKGF 798
           +C N  G+Y C C    Y ++  G +C D++EC    L C + +C NT G   CTCP+G+
Sbjct: 15  LCINTPGSYNCNCTHPLYTLNRNGYSCDDVDECETGQLRCTH-RCVNTAGGAHCTCPRGY 191

Query: 799 VYKPDLKTCEDIDECESSPCING----VCKNSPGSFICECS-PESTLDPTK 844
               D  TC+D +EC +S   NG    VC N+ GSF CEC+ P   L  T+
Sbjct: 192 QLADDNTTCQDTNECTNS---NGGCEDVCTNTEGSFECECTKPGFRLSQTR 335

 Score = 58.5 bits (140), Expect = 4e-08,   Method: Compositional matrix adjust.
 Identities = 43/137 (31%), Positives = 59/137 (43%), Gaps = 2/137 (1%)
 Frame = +3

Query: 1425 APGGYRCECDMG-FVPSADGKACEDIDECSLPNICVFGTCHNLPGLFRCECEIGYELDRS 1483
             PG Y C C    +  + +G +C+D+DEC    +     C N  G   C C  GY+L   
Sbjct: 27   TPGSYNCNCTHPLYTLNRNGYSCDDVDECETGQLRCTHRCVNTAGGAHCTCPRGYQLADD 206

Query: 1484 GGNCTDVNECLDPTTCISGNCVNTPGSYTCDC-PPDFELNPTRVGCVDTRSGNCYLDIRP 1542
               C D NEC +        C NT GS+ C+C  P F L+ TR     + S +     R 
Sbjct: 207  NTTCQDTNECTNSNGGCEDVCTNTEGSFECECTKPGFRLSQTRGSV*ISTSAS----TRA 374

Query: 1543 RGDNGDTACSNEIGVGV 1559
               +    C+  IGV V
Sbjct: 375  CAKDAAKTCTGRIGVTV 425

 Score = 56.6 bits (135), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 37/108 (34%), Positives = 51/108 (47%), Gaps = 2/108 (1%)
 Frame = +3

Query: 1170 HGRCVNLIGKYQCAC-NPGYHPTHDRLFCVDIDECSIMNGGCETFCTNSDGSYECSCQPG 1228
            H  C+N  G Y C C +P Y    +   C D+DEC      C   C N+ G   C+C  G
Sbjct: 9    HQLCINTPGSYNCNCTHPLYTLNRNGYSCDDVDECETGQLRCTHRCVNTAGGAHCTCPRG 188

Query: 1229 FALMPDQRSCTDIDECEDNPNICDGGQCTNIPGEYRCLCYD-GFMASE 1275
            + L  D  +C D +EC ++   C+   CTN  G + C C   GF  S+
Sbjct: 189  YQLADDNTTCQDTNECTNSNGGCE-DVCTNTEGSFECECTKPGFRLSQ 329

 Score = 46.2 bits (108), Expect(2) = 2e-07,   Method: Compositional matrix adjust.
 Identities = 31/79 (39%), Positives = 41/79 (51%), Gaps = 5/79 (6%)
 Frame = +3

Query: 1338 HAVCTNTAGSFKCSCS-PGWI--GDGIKCTDLDECSNGTHMCSQHADCKNTMGSYRCLCK 1394
            H +C NT GS+ C+C+ P +    +G  C D+DEC  G   C+    C NT G   C C 
Sbjct: 9    HQLCINTPGSYNCNCTHPLYTLNRNGYSCDDVDECETGQLRCTHR--CVNTAGGAHCTCP 182

Query: 1395 DGY--TGDGFTCTDLDECS 1411
             GY    D  TC D +EC+
Sbjct: 183  RGYQLADDNTTCQDTNECT 239

 Score = 30.0 bits (66), Expect(2) = 2e-07,   Method: Compositional matrix adjust.
 Identities = 15/35 (42%), Positives = 21/35 (60%)
 Frame = +2

Query: 1442 DGKACEDIDECSLPNICVFGTCHNLPGLFRCECEI 1476
            D + C DI+EC   ++C  G C NL G +RC C +
Sbjct: 329  DKRQCVDINECLNKSLCE-GRCENLYGSYRCHCTV 430

 Score = 45.8 bits (107), Expect(2) = 8e-07,   Method: Compositional matrix adjust.
 Identities = 30/82 (36%), Positives = 41/82 (50%)
 Frame = +3

Query: 1030 DINECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQCV 1089
            D++EC+     CTH +C NT G   C C  G+ L  +   C D +EC  S   C    C 
Sbjct: 99   DVDECETGQLRCTH-RCVNTAGGAHCTCPRGYQLADDNTTCQDTNECTNSNGGC-EDVCT 272

Query: 1090 NTPGDFECKCDEGYESGFMMMK 1111
            NT G FEC+C    + GF + +
Sbjct: 273  NTEGSFECECT---KPGFRLSQ 329

 Score = 27.7 bits (60), Expect(2) = 8e-07,   Method: Compositional matrix adjust.
 Identities = 15/33 (45%), Positives = 18/33 (54%)
 Frame = +2

Query: 1111 KNCMDIDECQRDPLLCRGGICHNTEGSYRCECP 1143
            + C+DI+EC    L    G C N  GSYRC C 
Sbjct: 335  RQCVDINECLNKSLC--EGRCENLYGSYRCHCT 427

 Score = 52.0 bits (123), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 33/89 (37%), Positives = 47/89 (52%), Gaps = 1/89 (1%)
 Frame = +3

Query: 235 FIPNIRTGACQDVDECQAIPGMCQGGNCINTVGSFECKCPAGHKFNEVSQKCEDIDECST 294
           +  N    +C DVDEC+     C    C+NT G   C CP G++  + +  C+D +EC+ 
Sbjct: 66  YTLNRNGYSCDDVDECETGQLRCTH-RCVNTAGGAHCTCPRGYQLADDNTTCQDTNECTN 242

Query: 295 IPGVCDGGECTNTVSSYFCKC-PPGFYTS 322
             G C+   CTNT  S+ C+C  PGF  S
Sbjct: 243 SNGGCE-DVCTNTEGSFECECTKPGFRLS 326

 Score = 51.2 bits (121), Expect = 6e-06,   Method: Compositional matrix adjust.
 Identities = 31/80 (38%), Positives = 41/80 (51%), Gaps = 1/80 (1%)
 Frame = +3

Query: 588 MCINEDGSFKCIC-KPGFQLASDGRYCKDINECETPGICMNGRCVNTDGSYRCECFPGLA 646
           +CIN  GS+ C C  P + L  +G  C D++ECET  +    RCVNT G   C C  G  
Sbjct: 15  LCINTPGSYNCNCTHPLYTLNRNGYSCDDVDECETGQLRCTHRCVNTAGGAHCTCPRGYQ 194

Query: 647 VGLDGRVCVDTHMRSTCYGG 666
           +  D   C DT+  +   GG
Sbjct: 195 LADDNTTCQDTNECTNSNGG 254

 Score = 50.1 bits (118), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 31/80 (38%), Positives = 42/80 (52%), Gaps = 1/80 (1%)
 Frame = +3

Query: 1768 DIDECREIPGVCENGVCINMVGSFRCECPVGFFYNDKLLVCEDIDECQNGPVCQRNAECI 1827
            D+DEC      C +  C+N  G   C CP G+   D    C+D +EC N      +  C 
Sbjct: 99   DVDECETGQLRCTH-RCVNTAGGAHCTCPRGYQLADDNTTCQDTNECTNSNGGCEDV-CT 272

Query: 1828 NTAGSYRCDC-KPGYRLTST 1846
            NT GS+ C+C KPG+RL+ T
Sbjct: 273  NTEGSFECECTKPGFRLSQT 332

 Score = 34.7 bits (78), Expect(2) = 2e-05,   Method: Compositional matrix adjust.
 Identities = 22/51 (43%), Positives = 30/51 (58%), Gaps = 3/51 (5%)
 Frame = +3

Query: 2129 DMDECKEPDV-CRHGQCINTDGSYRCECPFGYIL--EGNECVDTDECSVGN 2176
            D+DEC+   + C H +C+NT G   C CP GY L  +   C DT+EC+  N
Sbjct: 99   DVDECETGQLRCTH-RCVNTAGGAHCTCPRGYQLADDNTTCQDTNECTNSN 248

 Score = 34.3 bits (77), Expect(2) = 2e-05,   Method: Compositional matrix adjust.
 Identities = 19/31 (61%), Positives = 19/31 (61%)
 Frame = +2

Query: 2206 CEDINECAQNPLLCAFRCVNTYGSYECKCPV 2236
            C DINEC  N  LC  RC N YGSY C C V
Sbjct: 341  CVDINECL-NKSLCEGRCENLYGSYRCHCTV 430

 Score = 49.3 bits (116), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 37/99 (37%), Positives = 48/99 (48%), Gaps = 3/99 (3%)
 Frame = +3

Query: 1298 CENTKGSFICHCDMG-YSGKKGKTGCTDINECEIGAHNCGRHAVCTNTAGSFKCSCSPGW 1356
            C NT GS+ C+C    Y+  +    C D++ECE G   C     C NTAG   C+C  G+
Sbjct: 18   CINTPGSYNCNCTHPLYTLNRNGYSCDDVDECETGQLRCTHR--CVNTAGGAHCTCPRGY 191

Query: 1357 --IGDGIKCTDLDECSNGTHMCSQHADCKNTMGSYRCLC 1393
                D   C D +EC+N    C     C NT GS+ C C
Sbjct: 192  QLADDNTTCQDTNECTNSNGGCED--VCTNTEGSFECEC 302

 Score = 35.8 bits (81), Expect(2) = 7e-05,   Method: Compositional matrix adjust.
 Identities = 28/75 (37%), Positives = 37/75 (49%), Gaps = 1/75 (1%)
 Frame = +3

Query: 725 DINECALDPDICPNGICENLRGTYKCICNSGYEVDITGKNCVDINECVLNSLLCDNGQCR 784
           D++EC      C +  C N  G   C C  GY++      C D NEC  ++  C++  C 
Sbjct: 99  DVDECETGQLRCTH-RCVNTAGGAHCTCPRGYQLADDNTTCQDTNECTNSNGGCED-VCT 272

Query: 785 NTPGSFVCTCPK-GF 798
           NT GSF C C K GF
Sbjct: 273 NTEGSFECECTKPGF 317

 Score = 30.8 bits (68), Expect(2) = 7e-05,   Method: Compositional matrix adjust.
 Identities = 14/35 (40%), Positives = 21/35 (60%)
 Frame = +2

Query: 801 KPDLKTCEDIDECESSPCINGVCKNSPGSFICECS 835
           +PD + C DI+EC +     G C+N  GS+ C C+
Sbjct: 323 QPDKRQCVDINECLNKSLCEGRCENLYGSYRCHCT 427

 Score = 47.0 bits (110), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 29/70 (41%), Positives = 34/70 (48%), Gaps = 1/70 (1%)
 Frame = +3

Query: 1624 CINTFGSFQCRCPTGYY-LNEDTRVCDDVNECETPGICGPGTCYNTVGNYTCICPPDYMQ 1682
            CINT GS+ C C    Y LN +   CDDV+ECET  +     C NT G   C CP  Y  
Sbjct: 18   CINTPGSYNCNCTHPLYTLNRNGYSCDDVDECETGQLRCTHRCVNTAGGAHCTCPRGYQL 197

Query: 1683 VNGGNNCMDM 1692
             +    C D 
Sbjct: 198  ADDNTTCQDT 227

 Score = 46.6 bits (109), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 27/70 (38%), Positives = 35/70 (50%)
 Frame = +3

Query: 1607 EDIDECQELPGLCQGGKCINTFGSFQCRCPTGYYLNEDTRVCDDVNECETPGICGPGTCY 1666
            +D+DEC+     C   +C+NT G   C CP GY L +D   C D NEC          C 
Sbjct: 96   DDVDECETGQLRCTH-RCVNTAGGAHCTCPRGYQLADDNTTCQDTNECTNSNGGCEDVCT 272

Query: 1667 NTVGNYTCIC 1676
            NT G++ C C
Sbjct: 273  NTEGSFECEC 302

 Score = 35.4 bits (80), Expect(2) = 5e-04,   Method: Compositional matrix adjust.
 Identities = 28/80 (35%), Positives = 42/80 (52%), Gaps = 5/80 (6%)
 Frame = +3

Query: 453 DYCQLVRYLCQNGRCIPTPGSYRCECNKGFQL-DIRGECIDVDECEKNPCTGG---ECIN 508
           D C+  +  C + RC+ T G   C C +G+QL D    C D +EC  +   GG    C N
Sbjct: 105 DECETGQLRCTH-RCVNTAGGAHCTCPRGYQLADDNTTCQDTNECTNS--NGGCEDVCTN 275

Query: 509 NQGSYTCHC-RAGYQSTLTR 527
            +GS+ C C + G++ + TR
Sbjct: 276 TEGSFECECTKPGFRLSQTR 335

 Score = 28.5 bits (62), Expect(2) = 5e-04,   Method: Compositional matrix adjust.
 Identities = 18/43 (41%), Positives = 24/43 (55%)
 Frame = +2

Query: 519 AGYQSTLTRTECRDIDECLQNGRICNNGRCINTDGSFHCVCNA 561
           A  Q+   + +C DI+ECL N  +C  GRC N  GS+ C C  
Sbjct: 308 ARLQTQPDKRQCVDINECL-NKSLCE-GRCENLYGSYRCHCTV 430

 Score = 44.3 bits (103), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 27/71 (38%), Positives = 33/71 (46%), Gaps = 1/71 (1%)
 Frame = +3

Query: 262 CINTVGSFECKCPAG-HKFNEVSQKCEDIDECSTIPGVCDGGECTNTVSSYFCKCPPGFY 320
           CINT GS+ C C    +  N     C+D+DEC T    C    C NT     C CP G+ 
Sbjct: 18  CINTPGSYNCNCTHPLYTLNRNGYSCDDVDECETGQLRCTH-RCVNTAGGAHCTCPRGYQ 194

Query: 321 TSPDGTRCVDV 331
            + D T C D 
Sbjct: 195 LADDNTTCQDT 227

 Score = 43.1 bits (100), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 28/70 (40%), Positives = 36/70 (51%), Gaps = 3/70 (4%)
 Frame = +3

Query: 1991 CQNLDGSYRCICP-PGYSLQND--KCEDIDECVEEPEICALGTCSNTEGSFKCLCPEGFS 2047
            C N  GSY C C  P Y+L  +   C+D+DEC E  ++     C NT G   C CP G+ 
Sbjct: 18   CINTPGSYNCNCTHPLYTLNRNGYSCDDVDEC-ETGQLRCTHRCVNTAGGAHCTCPRGYQ 194

Query: 2048 LSSTGRRCQD 2057
            L+     CQD
Sbjct: 195  LADDNTTCQD 224

 Score = 28.9 bits (63), Expect(2) = 0.029,   Method: Compositional matrix adjust.
 Identities = 37/144 (25%), Positives = 51/144 (35%), Gaps = 1/144 (0%)
 Frame = +3

Query: 1504 CVNTPGSYTCDCP-PDFELNPTRVGCVDTRSGNCYLDIRPRGDNGDTACSNEIGVGVSKA 1562
            C+NTPGSY C+C  P + LN     C D              + G   C++         
Sbjct: 18   CINTPGSYNCNCTHPLYTLNRNGYSCDDV----------DECETGQLRCTHRC------- 146

Query: 1563 SCCCSLGKAWGTPCELCPSVNTSEYKILCPGGEGFRPNPITVILEDIDECQELPGLCQGG 1622
                 +  A G  C  CP               G++        +D +EC    G C+  
Sbjct: 147  -----VNTAGGAHC-TCP--------------RGYQLADDNTTCQDTNECTNSNGGCE-D 263

Query: 1623 KCINTFGSFQCRCPTGYYLNEDTR 1646
             C NT GSF+C C    +    TR
Sbjct: 264  VCTNTEGSFECECTKPGFRLSQTR 335

 Score = 28.9 bits (63), Expect(2) = 0.029,   Method: Compositional matrix adjust.
 Identities = 15/34 (44%), Positives = 18/34 (52%)
 Frame = +2

Query: 1644 DTRVCDDVNECETPGICGPGTCYNTVGNYTCICP 1677
            D R C D+NEC    +C  G C N  G+Y C C 
Sbjct: 329  DKRQCVDINECLNKSLC-EGRCENLYGSYRCHCT 427

 Score = 38.5 bits (88), Expect = 0.036,   Method: Compositional matrix adjust.
 Identities = 39/130 (30%), Positives = 56/130 (43%), Gaps = 3/130 (2%)
 Frame = +3

Query: 822 VCKNSPGSFICECS-PESTLDPTKTICIETIKGTCWQTVIDGRCEININGATLKSECCSS 880
           +C N+PGS+ C C+ P  TL+     C +  +    Q     RC                
Sbjct: 15  LCINTPGSYNCNCTHPLYTLNRNGYSCDDVDECETGQLRCTHRC---------------- 146

Query: 881 LGAAWGSPCTICQLDPICGKGFSRIK-GTQCEDINECEVFPGVCKNGLCVNSRGSFKCEC 939
           +  A G+ CT       C +G+      T C+D NEC    G C++ +C N+ GSF+CEC
Sbjct: 147 VNTAGGAHCT-------CPRGYQLADDNTTCQDTNECTNSNGGCED-VCTNTEGSFECEC 302

Query: 940 PN-GMTLDAT 948
              G  L  T
Sbjct: 303 TKPGFRLSQT 332

 Score = 35.4 bits (80), Expect = 0.32,   Method: Compositional matrix adjust.
 Identities = 18/39 (46%), Positives = 25/39 (64%)
 Frame = +2

Query: 1229 FALMPDQRSCTDIDECEDNPNICDGGQCTNIPGEYRCLC 1267
                PD+R C DI+EC  N ++C+ G+C N+ G YRC C
Sbjct: 314  LQTQPDKRQCVDINECL-NKSLCE-GRCENLYGSYRCHC 424

 Score = 32.0 bits (71), Expect(2) = 0.35,   Method: Compositional matrix adjust.
 Identities = 19/43 (44%), Positives = 23/43 (53%)
 Frame = +3

Query: 231 CRRGFIPNIRTGACQDVDECQAIPGMCQGGNCINTVGSFECKC 273
           C RG+        CQD +EC    G C+   C NT GSFEC+C
Sbjct: 177 CPRGYQLADDNTTCQDTNECTNSNGGCEDV-CTNTEGSFECEC 302

 Score = 21.9 bits (45), Expect(2) = 0.35,   Method: Compositional matrix adjust.
 Identities = 13/34 (38%), Positives = 18/34 (52%)
 Frame = +2

Query: 283 SQKCEDIDECSTIPGVCDGGECTNTVSSYFCKCP 316
            ++C DI+EC     +C+G  C N   SY C C 
Sbjct: 332 KRQCVDINECLN-KSLCEG-RCENLYGSYRCHCT 427

 Score = 35.4 bits (80), Expect = 0.36,   Method: Compositional matrix adjust.
 Identities = 26/73 (35%), Positives = 34/73 (46%), Gaps = 1/73 (1%)
 Frame = +3

Query: 2267 CKNLIGTYMCICG-PGYQRRPDGEGCIDENECQTKPGICENGRCLNTLGSYTCECNDGFT 2325
            C N  G+Y C C  P Y    +G  C D +EC+T    C + RC+NT G   C C  G+ 
Sbjct: 18   CINTPGSYNCNCTHPLYTLNRNGYSCDDVDECETGQLRCTH-RCVNTAGGAHCTCPRGYQ 194

Query: 2326 ASPTQDECLDNRE 2338
             +     C D  E
Sbjct: 195  LADDNTTCQDTNE 233

 Score = 32.0 bits (71), Expect = 4.2,   Method: Compositional matrix adjust.
 Identities = 18/50 (36%), Positives = 23/50 (46%)
 Frame = +3

Query: 906 KGTQCEDINECEVFPGVCKNGLCVNSRGSFKCECPNGMTLDATGRICLDI 955
            G  C+D++ECE     C +  CVN+ G   C CP G  L      C D 
Sbjct: 81  NGYSCDDVDECETGQLRCTH-RCVNTAGGAHCTCPRGYQLADDNTTCQDT 227

 Score = 31.2 bits (69), Expect = 5.7,   Method: Compositional matrix adjust.
 Identities = 18/33 (54%), Positives = 22/33 (66%)
 Frame = +2

Query: 763 KNCVDINECVLNSLLCDNGQCRNTPGSFVCTCP 795
           + CVDINEC LN  LC+ G+C N  GS+ C C 
Sbjct: 335 RQCVDINEC-LNKSLCE-GRCENLYGSYRCHCT 427

 Score = 30.8 bits (68), Expect = 9.2,   Method: Compositional matrix adjust.
 Identities = 15/30 (50%), Positives = 18/30 (60%)
 Frame = +2

Query: 1487 CTDVNECLDPTTCISGNCVNTPGSYTCDCP 1516
            C D+NECL+ + C  G C N  GSY C C 
Sbjct: 341  CVDINECLNKSLC-EGRCENLYGSYRCHCT 427
>11992
          Length = 1209

 Score = 95.9 bits (237), Expect = 2e-19,   Method: Compositional matrix adjust.
 Identities = 59/140 (42%), Positives = 75/140 (53%), Gaps = 10/140 (7%)
 Frame = +2

Query: 2390 KLCPHGRGFMTNGA----DIDECKV-IHDVCRNGECVNDRGSYHCICKTGYTPDITGTAC 2444
            +LCP  RGF+   +    D+DEC    H    N  CVN+ G Y C C  GY     G  C
Sbjct: 17   RLCP--RGFVRTASGECQDVDECASNTHRCYNNQRCVNNDGGYRCQCPKGYRTRGIGQPC 190

Query: 2445 VDLNECNQAPKPCNFICKNTEGSYQCSCPKGYILQEDGRSCKDLDECATKQHNC--QFLC 2502
            VD+NEC      C   C NT GSYQCSCPKGY L  DG SC D++EC  ++  C  + +C
Sbjct: 191  VDINECRLRSDICQHNCSNTRGSYQCSCPKGYRLAADGYSCTDINECWEERIQCKEEQMC 370

Query: 2503 VNTIGGFTC---KCPPGFTQ 2519
             NT G ++C    CP  + +
Sbjct: 371  FNTRGSYSCIDIPCPTNYVR 430

 Score = 90.5 bits (223), Expect = 8e-18,   Method: Compositional matrix adjust.
 Identities = 57/135 (42%), Positives = 73/135 (54%), Gaps = 6/135 (4%)
 Frame = +2

Query: 1918 CNHGFILSHNNDCIDVDECATGNGNLCRNGQCVNTVGSFQCRCNEGYEVAPDGRTCVDIN 1977
            C  GF+ + + +C DVDECA+       N +CVN  G ++C+C +GY     G+ CVDIN
Sbjct: 23   CPRGFVRTASGECQDVDECASNTHRCYNNQRCVNNDGGYRCQCPKGYRTRGIGQPCVDIN 202

Query: 1978 ECVLDPGKCAPGTCQNLDGSYRCICPPGYSLQND--KCEDIDECVEEPEICA-LGTCSNT 2034
            EC L    C    C N  GSY+C CP GY L  D   C DI+EC EE   C     C NT
Sbjct: 203  ECRLRSDICQ-HNCSNTRGSYQCSCPKGYRLAADGYSCTDINECWEERIQCKEEQMCFNT 379

Query: 2035 EGSFKCL---CPEGF 2046
             GS+ C+   CP  +
Sbjct: 380  RGSYSCIDIPCPTNY 424

 Score = 87.4 bits (215), Expect = 8e-17,   Method: Compositional matrix adjust.
 Identities = 62/138 (44%), Positives = 72/138 (52%), Gaps = 9/138 (6%)
 Frame = +2

Query: 2554 CQRGFSLDQSGASCEDVDECEGN-HRCQHG--CQNIIGGYRCSCPQGYLQHYQWNQCVDE 2610
            C RGF    SG  C+DVDEC  N HRC +   C N  GGYRC CP+GY        CVD 
Sbjct: 23   CPRGFVRTASG-ECQDVDECASNTHRCYNNQRCVNNDGGYRCQCPKGYRTRGIGQPCVDI 199

Query: 2611 NEC-LSAHVCGGASCHNTLGSYKCMCPTGFQYEQFSGGCQDINECGSSQAPCS--YGCSN 2667
            NEC L + +C   +C NT GSY+C CP G++       C DINEC   +  C     C N
Sbjct: 200  NECRLRSDICQ-HNCSNTRGSYQCSCPKGYRLAADGYSCTDINECWEERIQCKEEQMCFN 376

Query: 2668 TEGGYLC---GCPPGYFR 2682
            T G Y C    CP  Y R
Sbjct: 377  TRGSYSCIDIPCPTNYVR 430

 Score = 85.9 bits (211), Expect = 2e-16,   Method: Compositional matrix adjust.
 Identities = 51/118 (43%), Positives = 67/118 (56%), Gaps = 3/118 (2%)
 Frame = +2

Query: 529 ECRDIDECLQNGRIC-NNGRCINTDGSFHCVCNAGFHVTRDGKNCEDMDECSIRNMCLNG 587
           EC+D+DEC  N   C NN RC+N DG + C C  G+     G+ C D++EC +R+     
Sbjct: 56  ECQDVDECASNTHRCYNNQRCVNNDGGYRCQCPKGYRTRGIGQPCVDINECRLRSDICQH 235

Query: 588 MCINEDGSFKCICKPGFQLASDGRYCKDINECETPGI-CMNGR-CVNTDGSYRCECFP 643
            C N  GS++C C  G++LA+DG  C DINEC    I C   + C NT GSY C   P
Sbjct: 236 NCSNTRGSYQCSCPKGYRLAADGYSCTDINECWEERIQCKEEQMCFNTRGSYSCIDIP 409

 Score = 82.8 bits (203), Expect = 2e-15,   Method: Compositional matrix adjust.
 Identities = 65/182 (35%), Positives = 82/182 (45%), Gaps = 10/182 (5%)
 Frame = +2

Query: 473 SYRCE--CNKGFQLDIRGECIDVDECEKNP---CTGGECINNQGSYTCHCRAGYQSTLTR 527
           SY+C   C +GF     GEC DVDEC  N         C+NN G Y C C  GY++    
Sbjct: 2   SYQCVRLCPRGFVRTASGECQDVDECASNTHRCYNNQRCVNNDGGYRCQCPKGYRTRGIG 181

Query: 528 TECRDIDECLQNGRICNNGRCINTDGSFHCVCNAGFHVTRDGKNCEDMDEC-SIRNMCL- 585
             C DI+EC     IC +  C NT GS+ C C  G+ +  DG +C D++EC   R  C  
Sbjct: 182 QPCVDINECRLRSDICQHN-CSNTRGSYQCSCPKGYRLAADGYSCTDINECWEERIQCKE 358

Query: 586 NGMCINEDGSFKCI---CKPGFQLASDGRYCKDINECETPGICMNGRCVNTDGSYRCECF 642
             MC N  GS+ CI   C   +       YC  + EC  P  C  G        +R    
Sbjct: 359 EQMCFNTRGSYSCIDIPCPTNYVRDPATNYC--VLECVDPRSCPPGSKYADVIQFRTVAL 532

Query: 643 PG 644
           PG
Sbjct: 533 PG 538

 Score = 79.3 bits (194), Expect = 2e-14,   Method: Compositional matrix adjust.
 Identities = 65/202 (32%), Positives = 90/202 (44%), Gaps = 8/202 (3%)
 Frame = +2

Query: 1113 CMDIDECQRDPLLCRGG-ICHNTEGSYRCECPPGHQLSPNISACIDINECELSANLCPHG 1171
            C D+DEC  +   C     C N +G YRC+CP G++       C+DINEC L +++C H 
Sbjct: 59   CQDVDECASNTHRCYNNQRCVNNDGGYRCQCPKGYRTRGIGQPCVDINECRLRSDICQHN 238

Query: 1172 RCVNLIGKYQCACNPGYHPTHDRLFCVDIDECSIMNGGC--ETFCTNSDGSYEC---SCQ 1226
             C N  G YQC+C  GY    D   C DI+EC      C  E  C N+ GSY C    C 
Sbjct: 239  -CSNTRGSYQCSCPKGYRLAADGYSCTDINECWEERIQCKEEQMCFNTRGSYSCIDIPCP 415

Query: 1227 PGFALMPDQRSCTDIDECEDNPNICDGGQCTNIPGEYRCLCYDGFM-ASEDMKTCVDVNE 1285
              +   P    C  + EC D P  C  G       ++R +   G + A +D+      N 
Sbjct: 416  TNYVRDPATNYC--VLECVD-PRSCPPGSKYADVIQFRTVALPGGIPARQDLIRLTAYNH 586

Query: 1286 CD-LNPNICLSGTCENTKGSFI 1306
             D + P    +    + K +F 
Sbjct: 587  HDEMLPETTFTLLENDPKLTFF 652

 Score = 78.6 bits (192), Expect = 4e-14,   Method: Compositional matrix adjust.
 Identities = 49/134 (36%), Positives = 67/134 (50%), Gaps = 7/134 (5%)
 Frame = +2

Query: 2513 CPPGFTQHHTA-CIDNNECTSDINLCGSKGVCQNTPGSFTCECQRGFSLDQSGASCEDVD 2571
            CP GF +  +  C D +EC S+ + C +   C N  G + C+C +G+     G  C D++
Sbjct: 23   CPRGFVRTASGECQDVDECASNTHRCYNNQRCVNNDGGYRCQCPKGYRTRGIGQPCVDIN 202

Query: 2572 ECE-GNHRCQHGCQNIIGGYRCSCPQGYLQHYQWNQCVDENECLSAHV--CGGASCHNTL 2628
            EC   +  CQH C N  G Y+CSCP+GY        C D NEC    +       C NT 
Sbjct: 203  ECRLRSDICQHNCSNTRGSYQCSCPKGYRLAADGYSCTDINECWEERIQCKEEQMCFNTR 382

Query: 2629 GSYKCM---CPTGF 2639
            GSY C+   CPT +
Sbjct: 383  GSYSCIDIPCPTNY 424

 Score = 77.4 bits (189), Expect = 7e-14,   Method: Compositional matrix adjust.
 Identities = 55/127 (43%), Positives = 66/127 (51%), Gaps = 5/127 (3%)
 Frame = +2

Query: 1795 CPVGFFYNDKLLVCEDIDEC-QNGPVCQRNAECINTAGSYRCDCKPGYRLTSTGQ-CNDR 1852
            CP GF        C+D+DEC  N   C  N  C+N  G YRC C  GYR    GQ C D 
Sbjct: 23   CPRGFVRTASG-ECQDVDECASNTHRCYNNQRCVNNDGGYRCQCPKGYRTRGIGQPCVDI 199

Query: 1853 NECQEIPNICSHGQCIDTVGSFYCLCHTGFKTNVDQTMCLDINEC--ERDACG-NGTCRN 1909
            NEC+   +IC H  C +T GS+ C C  G++   D   C DINEC  ER  C     C N
Sbjct: 200  NECRLRSDICQHN-CSNTRGSYQCSCPKGYRLAADGYSCTDINECWEERIQCKEEQMCFN 376

Query: 1910 TIGSFNC 1916
            T GS++C
Sbjct: 377  TRGSYSC 397

 Score = 77.4 bits (189), Expect = 7e-14,   Method: Compositional matrix adjust.
 Identities = 53/144 (36%), Positives = 72/144 (50%), Gaps = 6/144 (4%)
 Frame = +2

Query: 1266 LCYDGFMASEDMKTCVDVNECDLNPNICLSGT-CENTKGSFICHCDMGYSGKKGKTGCTD 1324
            LC  GF+ +   + C DV+EC  N + C +   C N  G + C C  GY  +     C D
Sbjct: 20   LCPRGFVRTASGE-CQDVDECASNTHRCYNNQRCVNNDGGYRCQCPKGYRTRGIGQPCVD 196

Query: 1325 INECEIGAHNCGRHAVCTNTAGSFKCSCSPGW--IGDGIKCTDLDECSNGTHMCSQHADC 1382
            INEC + +  C  +  C+NT GS++CSC  G+    DG  CTD++EC      C +   C
Sbjct: 197  INECRLRSDICQHN--CSNTRGSYQCSCPKGYRLAADGYSCTDINECWEERIQCKEEQMC 370

Query: 1383 KNTMGSYRCL---CKDGYTGDGFT 1403
             NT GSY C+   C   Y  D  T
Sbjct: 371  FNTRGSYSCIDIPCPTNYVRDPAT 442

 Score = 76.6 bits (187), Expect = 1e-13,   Method: Compositional matrix adjust.
 Identities = 64/189 (33%), Positives = 79/189 (41%), Gaps = 5/189 (2%)
 Frame = +2

Query: 2111 QICPFGSGIIVGPDDSAVDMDECKE-PDVCRHGQ-CINTDGSYRCECPFGYILEGNECVD 2168
            ++CP   G +        D+DEC      C + Q C+N DG YRC+CP GY   G     
Sbjct: 17   RLCP--RGFVRTASGECQDVDECASNTHRCYNNQRCVNNDGGYRCQCPKGYRTRG----- 175

Query: 2169 TDECSVGNPCGNGTCKNVIXXXXXXXXXXXXXXXMMTCEDINECAQNPLLCAFRCVNTYG 2228
                 +G PC                             DINEC     +C   C NT G
Sbjct: 176  -----IGQPC----------------------------VDINECRLRSDICQHNCSNTRG 256

Query: 2229 SYECKCPVGYVLREDRRMCKDEDECAEGKHDCTEKQMECKNLIGTYMCI---CGPGYQRR 2285
            SY+C CP GY L  D   C D +EC E +  C E+QM C N  G+Y CI   C   Y R 
Sbjct: 257  SYQCSCPKGYRLAADGYSCTDINECWEERIQCKEEQM-CFNTRGSYSCIDIPCPTNYVRD 433

Query: 2286 PDGEGCIDE 2294
            P    C+ E
Sbjct: 434  PATNYCVLE 460

 Score = 76.3 bits (186), Expect = 2e-13,   Method: Compositional matrix adjust.
 Identities = 57/146 (39%), Positives = 75/146 (51%), Gaps = 9/146 (6%)
 Frame = +2

Query: 712 LCSSGPGMTSAG--TDINECALDPDICPNG-ICENLRGTYKCICNSGYEVDITGKNCVDI 768
           LC  G   T++G   D++ECA +   C N   C N  G Y+C C  GY     G+ CVDI
Sbjct: 20  LCPRGFVRTASGECQDVDECASNTHRCYNNQRCVNNDGGYRCQCPKGYRTRGIGQPCVDI 199

Query: 769 NECVLNSLLCDNGQCRNTPGSFVCTCPKGFVYKPDLKTCEDIDEC--ESSPCI-NGVCKN 825
           NEC L S +C +  C NT GS+ C+CPKG+    D  +C DI+EC  E   C    +C N
Sbjct: 200 NECRLRSDICQHN-CSNTRGSYQCSCPKGYRLAADGYSCTDINECWEERIQCKEEQMCFN 376

Query: 826 SPGSFIC---ECSPESTLDPTKTICI 848
           + GS+ C    C      DP    C+
Sbjct: 377 TRGSYSCIDIPCPTNYVRDPATNYCV 454

 Score = 75.9 bits (185), Expect = 2e-13,   Method: Compositional matrix adjust.
 Identities = 53/134 (39%), Positives = 73/134 (54%), Gaps = 4/134 (2%)
 Frame = +2

Query: 1137 SYRCE--CPPGHQLSPNISACIDINECELSANLCPHG-RCVNLIGKYQCACNPGYHPTHD 1193
            SY+C   CP G   + +   C D++EC  + + C +  RCVN  G Y+C C  GY     
Sbjct: 2    SYQCVRLCPRGFVRTAS-GECQDVDECASNTHRCYNNQRCVNNDGGYRCQCPKGYRTRGI 178

Query: 1194 RLFCVDIDECSIMNGGCETFCTNSDGSYECSCQPGFALMPDQRSCTDIDECEDNPNICDG 1253
               CVDI+EC + +  C+  C+N+ GSY+CSC  G+ L  D  SCTDI+EC +    C  
Sbjct: 179  GQPCVDINECRLRSDICQHNCSNTRGSYQCSCPKGYRLAADGYSCTDINECWEERIQCKE 358

Query: 1254 GQ-CTNIPGEYRCL 1266
             Q C N  G Y C+
Sbjct: 359  EQMCFNTRGSYSCI 400

 Score = 74.7 bits (182), Expect = 5e-13,   Method: Compositional matrix adjust.
 Identities = 58/155 (37%), Positives = 75/155 (48%), Gaps = 13/155 (8%)
 Frame = +2

Query: 2206 CEDINECAQNPLLCA--FRCVNTYGSYECKCPVGYVLREDRRMCKDEDECAEGKHDCTEK 2263
            C+D++ECA N   C    RCVN  G Y C+CP GY  R   + C D +EC      C   
Sbjct: 59   CQDVDECASNTHRCYNNQRCVNNDGGYRCQCPKGYRTRGIGQPCVDINECRLRSDIC--- 229

Query: 2264 QMECKNLIGTYMCICGPGYQRRPDGEGCIDENECQTKPGIC-ENGRCLNTLGSYTC---E 2319
            Q  C N  G+Y C C  GY+   DG  C D NEC  +   C E   C NT GSY+C    
Sbjct: 230  QHNCSNTRGSYQCSCPKGYRLAADGYSCTDINECWEERIQCKEEQMCFNTRGSYSCIDIP 409

Query: 2320 CNDGFTASPTQD----ECLDNRE---GYCFSEVLQ 2347
            C   +   P  +    EC+D R    G  +++V+Q
Sbjct: 410  CPTNYVRDPATNYCVLECVDPRSCPPGSKYADVIQ 514

 Score = 72.8 bits (177), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 40/102 (39%), Positives = 55/102 (53%), Gaps = 1/102 (0%)
 Frame = +2

Query: 231 CRRGFIPNIRTGACQDVDECQAIPGMCQGGN-CINTVGSFECKCPAGHKFNEVSQKCEDI 289
           C RGF+    +G CQDVDEC +    C     C+N  G + C+CP G++   + Q C DI
Sbjct: 23  CPRGFV-RTASGECQDVDECASNTHRCYNNQRCVNNDGGYRCQCPKGYRTRGIGQPCVDI 199

Query: 290 DECSTIPGVCDGGECTNTVSSYFCKCPPGFYTSPDGTRCVDV 331
           +EC     +C    C+NT  SY C CP G+  + DG  C D+
Sbjct: 200 NECRLRSDICQHN-CSNTRGSYQCSCPKGYRLAADGYSCTDI 322

 Score = 71.6 bits (174), Expect = 5e-12,   Method: Compositional matrix adjust.
 Identities = 60/170 (35%), Positives = 81/170 (47%), Gaps = 17/170 (10%)
 Frame = +2

Query: 1388 SYRC--LCKDGY--TGDGFTCTDLDECSEXXXXXXXXXX-XXAPGGYRCECDMGFVPSAD 1442
            SY+C  LC  G+  T  G  C D+DEC+                GGYRC+C  G+     
Sbjct: 2    SYQCVRLCPRGFVRTASG-ECQDVDECASNTHRCYNNQRCVNNDGGYRCQCPKGYRTRGI 178

Query: 1443 GKACEDIDECSLPNICVFGTCHNLPGLFRCECEIGYELDRSGGNCTDVNECLDPTTCISG 1502
            G+ C DI+EC L +      C N  G ++C C  GY L   G +CTD+NEC +       
Sbjct: 179  GQPCVDINECRLRSDICQHNCSNTRGSYQCSCPKGYRLAADGYSCTDINECWEERIQCKE 358

Query: 1503 N--CVNTPGSYTC---DCPPDFELNPTR----VGCVDTRS---GNCYLDI 1540
               C NT GSY+C    CP ++  +P      + CVD RS   G+ Y D+
Sbjct: 359  EQMCFNTRGSYSCIDIPCPTNYVRDPATNYCVLECVDPRSCPPGSKYADV 508

 Score = 70.1 bits (170), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 57/194 (29%), Positives = 89/194 (45%), Gaps = 5/194 (2%)
 Frame = +2

Query: 1008 ELCPRGPGFATKDITNGKPFFKDINECKMIPSLCTHG-KCRNTIGSFKCRCDSGFALDSE 1066
             LCPRG       +       +D++EC      C +  +C N  G ++C+C  G+     
Sbjct: 17   RLCPRG------FVRTASGECQDVDECASNTHRCYNNQRCVNNDGGYRCQCPKGYRTRGI 178

Query: 1067 ERNCTDIDECRISPDLCGRGQCVNTPGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLC 1126
             + C DI+ECR+  D+C +  C NT G ++C C +GY        +C DI+EC  + + C
Sbjct: 179  GQPCVDINECRLRSDIC-QHNCSNTRGSYQCSCPKGYRLA-ADGYSCTDINECWEERIQC 352

Query: 1127 R-GGICHNTEGSYRC---ECPPGHQLSPNISACIDINECELSANLCPHGRCVNLIGKYQC 1182
            +   +C NT GSY C    CP  +   P  + C  + EC +    CP G     + +++ 
Sbjct: 353  KEEQMCFNTRGSYSCIDIPCPTNYVRDPATNYC--VLEC-VDPRSCPPGSKYADVIQFRT 523

Query: 1183 ACNPGYHPTHDRLF 1196
               PG  P    L 
Sbjct: 524  VALPGGIPARQDLI 565

 Score = 68.6 bits (166), Expect = 3e-11,   Method: Compositional matrix adjust.
 Identities = 49/121 (40%), Positives = 63/121 (52%), Gaps = 2/121 (1%)
 Frame = +2

Query: 2229 SYECK--CPVGYVLREDRRMCKDEDECAEGKHDCTEKQMECKNLIGTYMCICGPGYQRRP 2286
            SY+C   CP G+V R     C+D DECA   H C   Q  C N  G Y C C  GY+ R 
Sbjct: 2    SYQCVRLCPRGFV-RTASGECQDVDECASNTHRCYNNQ-RCVNNDGGYRCQCPKGYRTRG 175

Query: 2287 DGEGCIDENECQTKPGICENGRCLNTLGSYTCECNDGFTASPTQDECLDNREGYCFSEVL 2346
             G+ C+D NEC+ +  IC++  C NT GSY C C  G+  +     C D  E  C+ E +
Sbjct: 176  IGQPCVDINECRLRSDICQHN-CSNTRGSYQCSCPKGYRLAADGYSCTDINE--CWEERI 346

Query: 2347 Q 2347
            Q
Sbjct: 347  Q 349

 Score = 67.8 bits (164), Expect = 6e-11,   Method: Compositional matrix adjust.
 Identities = 48/114 (42%), Positives = 61/114 (53%), Gaps = 4/114 (3%)
 Frame = +2

Query: 1768 DIDECREIPGVC-ENGVCINMVGSFRCECPVGFFYNDKLLVCEDIDECQ-NGPVCQRNAE 1825
            D+DEC      C  N  C+N  G +RC+CP G+        C DI+EC+    +CQ N  
Sbjct: 65   DVDECASNTHRCYNNQRCVNNDGGYRCQCPKGYRTRGIGQPCVDINECRLRSDICQHN-- 238

Query: 1826 CINTAGSYRCDCKPGYRLTSTG-QCNDRNECQEIPNICSHGQ-CIDTVGSFYCL 1877
            C NT GSY+C C  GYRL + G  C D NEC E    C   Q C +T GS+ C+
Sbjct: 239  CSNTRGSYQCSCPKGYRLAADGYSCTDINECWEERIQCKEEQMCFNTRGSYSCI 400

 Score = 64.7 bits (156), Expect = 5e-10,   Method: Compositional matrix adjust.
 Identities = 43/109 (39%), Positives = 57/109 (52%), Gaps = 4/109 (3%)
 Frame = +2

Query: 554 SFHCV--CNAGFHVTRDGKNCEDMDEC-SIRNMCLNGM-CINEDGSFKCICKPGFQLASD 609
           S+ CV  C  GF  T  G+ C+D+DEC S  + C N   C+N DG ++C C  G++    
Sbjct: 2   SYQCVRLCPRGFVRTASGE-CQDVDECASNTHRCYNNQRCVNNDGGYRCQCPKGYRTRGI 178

Query: 610 GRYCKDINECETPGICMNGRCVNTDGSYRCECFPGLAVGLDGRVCVDTH 658
           G+ C DINEC          C NT GSY+C C  G  +  DG  C D +
Sbjct: 179 GQPCVDINECRLRSDICQHNCSNTRGSYQCSCPKGYRLAADGYSCTDIN 325

 Score = 63.2 bits (152), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 37/96 (38%), Positives = 48/96 (50%), Gaps = 2/96 (2%)
 Frame = +2

Query: 2594 CPQGYLQHYQWNQCVDENECLS-AHVC-GGASCHNTLGSYKCMCPTGFQYEQFSGGCQDI 2651
            CP+G+++     +C D +EC S  H C     C N  G Y+C CP G++       C DI
Sbjct: 23   CPRGFVRTAS-GECQDVDECASNTHRCYNNQRCVNNDGGYRCQCPKGYRTRGIGQPCVDI 199

Query: 2652 NECGSSQAPCSYGCSNTEGGYLCGCPPGYFRIGQGH 2687
            NEC      C + CSNT G Y C CP GY     G+
Sbjct: 200  NECRLRSDICQHNCSNTRGSYQCSCPKGYRLAADGY 307

 Score = 62.8 bits (151), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 43/112 (38%), Positives = 52/112 (46%), Gaps = 7/112 (6%)
 Frame = +2

Query: 703 AQNSAEYQALCSSGPGMTSAG---TDINECALDPDICPNGICENLRGTYKCICNSGYEVD 759
             N   Y+  C  G      G    DINEC L  DIC +  C N RG+Y+C C  GY + 
Sbjct: 119 VNNDGGYRCQCPKGYRTRGIGQPCVDINECRLRSDICQHN-CSNTRGSYQCSCPKGYRLA 295

Query: 760 ITGKNCVDINECVLNSLLCDNGQ-CRNTPGSFVCT---CPKGFVYKPDLKTC 807
             G +C DINEC    + C   Q C NT GS+ C    CP  +V  P    C
Sbjct: 296 ADGYSCTDINECWEERIQCKEEQMCFNTRGSYSCIDIPCPTNYVRDPATNYC 451

 Score = 62.0 bits (149), Expect = 4e-09,   Method: Compositional matrix adjust.
 Identities = 44/113 (38%), Positives = 59/113 (52%), Gaps = 5/113 (4%)
 Frame = +2

Query: 1583 NTSEYKILCPGGEGFRPNPITVILEDIDECQELPGLCQGGKCINTFGSFQCRCPTGYYLN 1642
            N   Y+  CP  +G+R   I     DI+EC+    +CQ   C NT GS+QC CP GY L 
Sbjct: 125  NDGGYRCQCP--KGYRTRGIGQPCVDINECRLRSDICQHN-CSNTRGSYQCSCPKGYRLA 295

Query: 1643 EDTRVCDDVNECETPGI--CGPGTCYNTVGNYTCI---CPPDYMQVNGGNNCM 1690
             D   C D+NEC    I       C+NT G+Y+CI   CP +Y++    N C+
Sbjct: 296  ADGYSCTDINECWEERIQCKEEQMCFNTRGSYSCIDIPCPTNYVRDPATNYCV 454

 Score = 59.3 bits (142), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 36/98 (36%), Positives = 53/98 (54%), Gaps = 3/98 (3%)
 Frame = +2

Query: 464 NGRCIPTPGSYRCECNKGFQLDIRGE-CIDVDECE-KNPCTGGECINNQGSYTCHCRAGY 521
           N RC+   G YRC+C KG++    G+ C+D++EC  ++      C N +GSY C C  GY
Sbjct: 107 NQRCVNNDGGYRCQCPKGYRTRGIGQPCVDINECRLRSDICQHNCSNTRGSYQCSCPKGY 286

Query: 522 QSTLTRTECRDIDECLQNGRICNNGR-CINTDGSFHCV 558
           +       C DI+EC +    C   + C NT GS+ C+
Sbjct: 287 RLAADGYSCTDINECWEERIQCKEEQMCFNTRGSYSCI 400

 Score = 52.4 bits (124), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 30/87 (34%), Positives = 42/87 (48%), Gaps = 1/87 (1%)
 Frame = +2

Query: 1607 EDIDECQELPGLCQGG-KCINTFGSFQCRCPTGYYLNEDTRVCDDVNECETPGICGPGTC 1665
            +D+DEC      C    +C+N  G ++C+CP GY      + C D+NEC          C
Sbjct: 62   QDVDECASNTHRCYNNQRCVNNDGGYRCQCPKGYRTRGIGQPCVDINECRLRSDICQHNC 241

Query: 1666 YNTVGNYTCICPPDYMQVNGGNNCMDM 1692
             NT G+Y C CP  Y     G +C D+
Sbjct: 242  SNTRGSYQCSCPKGYRLAADGYSCTDI 322

 Score = 50.1 bits (118), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 33/90 (36%), Positives = 44/90 (48%), Gaps = 4/90 (4%)
 Frame = +2

Query: 244 CQDVDECQAIPGMCQGGNCINTVGSFECKCPAGHKFNEVSQKCEDIDECSTIPGVCDGGE 303
           C D++EC+    +CQ  NC NT GS++C CP G++       C DI+EC      C   +
Sbjct: 188 CVDINECRLRSDICQH-NCSNTRGSYQCSCPKGYRLAADGYSCTDINECWEERIQCKEEQ 364

Query: 304 -CTNTVSSYFC---KCPPGFYTSPDGTRCV 329
            C NT  SY C    CP  +   P    CV
Sbjct: 365 MCFNTRGSYSCIDIPCPTNYVRDPATNYCV 454

 Score = 48.5 bits (114), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 27/59 (45%), Positives = 36/59 (61%), Gaps = 1/59 (1%)
 Frame = +2

Query: 898 CGKGF-SRIKGTQCEDINECEVFPGVCKNGLCVNSRGSFKCECPNGMTLDATGRICLDI 955
           C KG+ +R  G  C DINEC +   +C++  C N+RGS++C CP G  L A G  C DI
Sbjct: 149 CPKGYRTRGIGQPCVDINECRLRSDICQHN-CSNTRGSYQCSCPKGYRLAADGYSCTDI 322

 Score = 47.8 bits (112), Expect = 6e-05,   Method: Compositional matrix adjust.
 Identities = 46/161 (28%), Positives = 65/161 (40%), Gaps = 2/161 (1%)
 Frame = +2

Query: 897  ICGKGFSRIKGTQCEDINECEVFPGVCKNG-LCVNSRGSFKCECPNGMTLDATGRICLDI 955
            +C +GF R    +C+D++EC      C N   CVN+ G ++C+CP G      G+ C+DI
Sbjct: 20   LCPRGFVRTASGECQDVDECASNTHRCYNNQRCVNNDGGYRCQCPKGYRTRGIGQPCVDI 199

Query: 956  RLETCFLKYDDEECTLPIAGRHRMDACCCSVGAAWGTEECEECPLRNSREYEELCPRGPG 1015
                        EC L      R D C  +     G+ +C              CP+G  
Sbjct: 200  -----------NECRL------RSDICQHNCSNTRGSYQCS-------------CPKGYR 289

Query: 1016 FATKDITNGKPFFKDINECKMIPSLCTHGK-CRNTIGSFKC 1055
             A    +       DINEC      C   + C NT GS+ C
Sbjct: 290  LAADGYS-----CTDINECWEERIQCKEEQMCFNTRGSYSC 397

 Score = 47.8 bits (112), Expect = 6e-05,   Method: Compositional matrix adjust.
 Identities = 28/70 (40%), Positives = 38/70 (54%), Gaps = 1/70 (1%)
 Frame = +2

Query: 1767 VDIDECREIPGVCENGVCINMVGSFRCECPVGFFYNDKLLVCEDIDECQNGPV-CQRNAE 1825
            VDI+ECR    +C++  C N  GS++C CP G+        C DI+EC    + C+    
Sbjct: 191  VDINECRLRSDICQHN-CSNTRGSYQCSCPKGYRLAADGYSCTDINECWEERIQCKEEQM 367

Query: 1826 CINTAGSYRC 1835
            C NT GSY C
Sbjct: 368  CFNTRGSYSC 397

 Score = 47.4 bits (111), Expect = 9e-05,   Method: Compositional matrix adjust.
 Identities = 46/141 (32%), Positives = 65/141 (46%), Gaps = 5/141 (3%)
 Frame = +2

Query: 2037 SFKC--LCPEGFSLSSTGRRCQDLRMSYCYAKFEGGKCSSPKSRNHSKQECCCALKGEGW 2094
            S++C  LCP GF  +++G  CQD+            +C+S   R ++ Q C         
Sbjct: 2    SYQCVRLCPRGFVRTASGE-CQDV-----------DECASNTHRCYNNQRC--------- 118

Query: 2095 GDPCELCPTEPDEAFRQICPFGSGIIVGPDDSAVDMDECK-EPDVCRHGQCINTDGSYRC 2153
                       D  +R  CP G     G     VD++EC+   D+C+H  C NT GSY+C
Sbjct: 119  --------VNNDGGYRCQCPKGYRT-RGIGQPCVDINECRLRSDICQHN-CSNTRGSYQC 268

Query: 2154 ECPFGYIL--EGNECVDTDEC 2172
             CP GY L  +G  C D +EC
Sbjct: 269  SCPKGYRLAADGYSCTDINEC 331

 Score = 45.8 bits (107), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 53/183 (28%), Positives = 71/183 (38%), Gaps = 10/183 (5%)
 Frame = +2

Query: 2273 TYMCI--CGPGYQRRPDGEGCIDENECQTKPGIC-ENGRCLNTLGSYTCECNDGFTASPT 2329
            +Y C+  C  G+ R   GE C D +EC +    C  N RC+N  G Y C+C  G+     
Sbjct: 2    SYQCVRLCPRGFVRTASGE-CQDVDECASNTHRCYNNQRCVNNDGGYRCQCPKGYRTRGI 178

Query: 2330 QDECLDNREGYCFSEVLQNMCQIGSSNRNPVTKSECCCDGGRGWGPHCEICPFEGTVAYK 2389
               C+D  E    S++ Q+ C                    RG              +Y+
Sbjct: 179  GQPCVDINECRLRSDICQHNCS-----------------NTRG--------------SYQ 265

Query: 2390 KLCPHGRGFMTNG---ADIDECKVIHDVCRNGE-CVNDRGSYHCI---CKTGYTPDITGT 2442
              CP G     +G    DI+EC      C+  + C N RGSY CI   C T Y  D    
Sbjct: 266  CSCPKGYRLAADGYSCTDINECWEERIQCKEEQMCFNTRGSYSCIDIPCPTNYVRDPATN 445

Query: 2443 ACV 2445
             CV
Sbjct: 446  YCV 454

 Score = 38.5 bits (88), Expect = 0.043,   Method: Compositional matrix adjust.
 Identities = 34/116 (29%), Positives = 49/116 (42%), Gaps = 13/116 (11%)
 Frame = +2

Query: 268 SFECK--CPAGHKFNEVSQKCEDIDECSTIPGVC-DGGECTNTVSSYFCKCPPGFYTSPD 324
           S++C   CP G      S +C+D+DEC++    C +   C N    Y C+CP G+ T   
Sbjct: 2   SYQCVRLCPRGF-VRTASGECQDVDECASNTHRCYNNQRCVNNDGGYRCQCPKGYRTRGI 178

Query: 325 GTRCVDV-----RPGYCYTALANGRCSNQLP-----QSITKMQCCCDLGRCWSPGV 370
           G  CVD+     R   C    +N R S Q       +       C D+  CW   +
Sbjct: 179 GQPCVDINECRLRSDICQHNCSNTRGSYQCSCPKGYRLAADGYSCTDINECWEERI 346
>34726
          Length = 626

 Score = 85.1 bits (209), Expect = 4e-16,   Method: Compositional matrix adjust.
 Identities = 62/170 (36%), Positives = 80/170 (47%), Gaps = 9/170 (5%)
 Frame = -1

Query: 2439 ITGTACVDLNECNQAPKPCNFICKNTEGSYQCSCPKGYILQE-DGRSCKDLDECATKQHN 2497
            + G  C D++EC  +P      C NT+GS+ CSCP  Y +   D   C D+DECA    N
Sbjct: 542  VRGCQCFDVDECQNSPCDSVATCTNTDGSFVCSCPTHYRMDTTDMTQCTDIDECAENTDN 363

Query: 2498 CQFLCVNTIGGFTCKCPPGFTQHHTACIDNNECTSDINL--CGS-----KGVCQNTPGSF 2550
            C+ +C NT GGFTC C  GF  + T    N+ C  D N   C S        CQN  G  
Sbjct: 362  CEQVCNNTEGGFTCDCVAGFXLNATT---NSTCDKDANQDPCASIXNTCSYACQNDSGXA 192

Query: 2551 TCECQRGFSLDQSGASCEDVDECEGNHRCQHGCQNII-GGYRCSCPQGYL 2599
             C C +GF+L  +  + +          C      I+ GGY CSC  GY 
Sbjct: 191  VCVCPKGFALTTTKQAVK--ISMSAVRTCVLSLAPIMTGGYTCSCLPGYF 48

 Score = 75.9 bits (185), Expect = 2e-13,   Method: Compositional matrix adjust.
 Identities = 65/192 (33%), Positives = 86/192 (44%), Gaps = 9/192 (4%)
 Frame = -1

Query: 476 CECN-KGFQLDIRG-ECIDVDECEKNPC-TGGECINNQGSYTCHCRAGYQ-STLTRTECR 531
           CEC  +G    +RG +C DVDEC+ +PC +   C N  GS+ C C   Y+  T   T+C 
Sbjct: 575 CECRGRGTCDRVRGCQCFDVDECQNSPCDSVATCTNTDGSFVCSCPTHYRMDTTDMTQCT 396

Query: 532 DIDECLQNGRICNNGRCINTDGSFHCVCNAGFHVTRDGKNCEDMDE-----CSIRNMCLN 586
           DIDEC +N   C    C NT+G F C C AGF +     +  D D       SI N C +
Sbjct: 395 DIDECAENTDNCEQ-VCNNTEGGFTCDCVAGFXLNATTNSTCDKDANQDPCASIXNTC-S 222

Query: 587 GMCINEDGSFKCICKPGFQLASDGRYCKDINECETPGICMNGRCVNTDGSYRCECFPGLA 646
             C N+ G   C+C  GF L +  +  K          C+        G Y C C PG  
Sbjct: 221 YACQNDSGXAVCVCPKGFALTTTKQAVKI--SMSAVRTCVLSLAPIMTGGYTCSCLPGYF 48

Query: 647 VGLDGRVCVDTH 658
           +  D     + H
Sbjct: 47  LEEDKLPAANVH 12

 Score = 72.0 bits (175), Expect = 3e-12,   Method: Compositional matrix adjust.
 Identities = 54/168 (32%), Positives = 72/168 (42%), Gaps = 10/168 (5%)
 Frame = -1

Query: 2524 CIDNNECTSDINLCGSKGVCQNTPGSFTCECQRGFSLDQSGAS-CEDVDEC-EGNHRCQH 2581
            C D +EC +  + C S   C NT GSF C C   + +D +  + C D+DEC E    C+ 
Sbjct: 527  CFDVDECQN--SPCDSVATCTNTDGSFVCSCPTHYRMDTTDMTQCTDIDECAENTDNCEQ 354

Query: 2582 GCQNIIGGYRCSCPQGYLQHYQWNQCVDENE----CLSAHVCGGASCHNTLGSYKCMCPT 2637
             C N  GG+ C C  G+  +   N   D++     C S       +C N  G   C+CP 
Sbjct: 353  VCNNTEGGFTCDCVAGFXLNATTNSTCDKDANQDPCASIXNTCSYACQNDSGXAVCVCPK 174

Query: 2638 GFQYEQFSGGCQ----DINECGSSQAPCSYGCSNTEGGYLCGCPPGYF 2681
            GF         +     +  C  S AP         GGY C C PGYF
Sbjct: 173  GFALTTTKQAVKISMSAVRTCVLSLAPI------MTGGYTCSCLPGYF 48

 Score = 65.1 bits (157), Expect = 4e-10,   Method: Compositional matrix adjust.
 Identities = 55/170 (32%), Positives = 73/170 (42%), Gaps = 4/170 (2%)
 Frame = -1

Query: 1070 CTDIDECRISPDLCGRGQCVNTPGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRGG 1129
            C D+DEC+ SP       C NT G F C C   Y      M  C DIDEC  +   C   
Sbjct: 527  CFDVDECQNSP-CDSVATCTNTDGSFVCSCPTHYRMDTTDMTQCTDIDECAENTDNCE-Q 354

Query: 1130 ICHNTEGSYRCECPPGHQLSPNISACIDINE----CELSANLCPHGRCVNLIGKYQCACN 1185
            +C+NTEG + C+C  G  L+   ++  D +     C    N C +  C N  G   C C 
Sbjct: 353  VCNNTEGGFTCDCVAGFXLNATTNSTCDKDANQDPCASIXNTCSYA-CQNDSGXAVCVCP 177

Query: 1186 PGYHPTHDRLFCVDIDECSIMNGGCETFCTNSDGSYECSCQPGFALMPDQ 1235
             G+  T  +   V I   S +     +      G Y CSC PG+ L  D+
Sbjct: 176  KGFALTTTKQA-VKISM-SAVRTCVLSLAPIMTGGYTCSCLPGYFLEEDK 33

 Score = 62.4 bits (150), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 55/170 (32%), Positives = 71/170 (41%), Gaps = 8/170 (4%)
 Frame = -1

Query: 1808 CEDIDECQNGPVCQRNAECINTAGSYRCDCKPGYRLTSTG--QCNDRNECQEIPNICSHG 1865
            C D+DECQN P C   A C NT GS+ C C   YR+ +T   QC D +EC E  + C   
Sbjct: 527  CFDVDECQNSP-CDSVATCTNTDGSFVCSCPTHYRMDTTDMTQCTDIDECAENTDNCEQ- 354

Query: 1866 QCIDTVGSFYCLCHTGFKTNVDQTMCLDINECERDACG------NGTCRNTIGSFNCRCN 1919
             C +T G F C C  GF  N       D  +  +D C       +  C+N  G   C C 
Sbjct: 353  VCNNTEGGFTCDCVAGFXLNATTNSTCD-KDANQDPCASIXNTCSYACQNDSGXAVCVCP 177

Query: 1920 HGFILSHNNDCIDVDECATGNGNLCRNGQCVNTVGSFQCRCNEGYEVAPD 1969
             GF L+     + +   A      C         G + C C  GY +  D
Sbjct: 176  KGFALTTTKQAVKISMSAV---RTCVLSLAPIMTGGYTCSCLPGYFLEED 36

 Score = 62.0 bits (149), Expect = 4e-09,   Method: Compositional matrix adjust.
 Identities = 50/138 (36%), Positives = 62/138 (44%), Gaps = 8/138 (5%)
 Frame = -1

Query: 2551 TCECQ-RGFSLDQSGASCEDVDECEGNHRCQH--GCQNIIGGYRCSCPQGY-LQHYQWNQ 2606
            TCEC+ RG      G  C DVDEC+ N  C     C N  G + CSCP  Y +      Q
Sbjct: 578  TCECRGRGTCDRVRGCQCFDVDECQ-NSPCDSVATCTNTDGSFVCSCPTHYRMDTTDMTQ 402

Query: 2607 CVDENECLSAHVCGGASCHNTLGSYKCMCPTGFQYEQFSGGC--QDINE--CGSSQAPCS 2662
            C D +EC          C+NT G + C C  GF     +     +D N+  C S    CS
Sbjct: 401  CTDIDECAENTDNCEQVCNNTEGGFTCDCVAGFXLNATTNSTCDKDANQDPCASIXNTCS 222

Query: 2663 YGCSNTEGGYLCGCPPGY 2680
            Y C N  G  +C CP G+
Sbjct: 221  YACQNDSGXAVCVCPKGF 168

 Score = 59.3 bits (142), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 61/173 (35%), Positives = 79/173 (45%), Gaps = 8/173 (4%)
 Frame = -1

Query: 1848 QCNDRNECQEIPNICSHGQCIDTVGSFYCLCHTGFKTNV-DQTMCLDINECER--DACGN 1904
            QC D +ECQ  P   S   C +T GSF C C T ++ +  D T C DI+EC    D C  
Sbjct: 530  QCFDVDECQNSPCD-SVATCTNTDGSFVCSCPTHYRMDTTDMTQCTDIDECAENTDNC-E 357

Query: 1905 GTCRNTIGSFNCRCNHGFIL--SHNNDC---IDVDECATGNGNLCRNGQCVNTVGSFQCR 1959
              C NT G F C C  GF L  + N+ C    + D CA+   N C    C N  G   C 
Sbjct: 356  QVCNNTEGGFTCDCVAGFXLNATTNSTCDKDANQDPCASI-XNTCSYA-CQNDSGXAVCV 183

Query: 1960 CNEGYEVAPDGRTCVDINECVLDPGKCAPGTCQNLDGSYRCICPPGYSLQNDK 2012
            C +G+ +    +  V I+   +    C       + G Y C C PGY L+ DK
Sbjct: 182  CPKGFALTTTKQA-VKISMSAV--RTCVLSLAPIMTGGYTCSCLPGYFLEEDK 33

 Score = 57.4 bits (137), Expect = 8e-08,   Method: Compositional matrix adjust.
 Identities = 35/82 (42%), Positives = 45/82 (54%), Gaps = 3/82 (3%)
 Frame = -1

Query: 1973 CVDINECVLDPGKCAPGTCQNLDGSYRCICPPGYSLQN---DKCEDIDECVEEPEICALG 2029
            C D++EC   P   +  TC N DGS+ C CP  Y +      +C DIDEC E  + C   
Sbjct: 527  CFDVDECQNSPCD-SVATCTNTDGSFVCSCPTHYRMDTTDMTQCTDIDECAENTDNCE-Q 354

Query: 2030 TCSNTEGSFKCLCPEGFSLSST 2051
             C+NTEG F C C  GF L++T
Sbjct: 353  VCNNTEGGFTCDCVAGFXLNAT 288

 Score = 55.5 bits (132), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 53/171 (30%), Positives = 70/171 (40%), Gaps = 6/171 (3%)
 Frame = -1

Query: 1155 CIDINECELSANLCPH-GRCVNLIGKYQCACNPGYH-PTHDRLFCVDIDECSIMNGGCET 1212
            C D++EC+ S   C     C N  G + C+C   Y   T D   C DIDEC+     CE 
Sbjct: 527  CFDVDECQNSP--CDSVATCTNTDGSFVCSCPTHYRMDTTDMTQCTDIDECAENTDNCEQ 354

Query: 1213 FCTNSDGSYECSCQPGFALMPDQRSCTDIDE----CEDNPNICDGGQCTNIPGEYRCLCY 1268
             C N++G + C C  GF L     S  D D     C    N C    C N  G   C+C 
Sbjct: 353  VCNNTEGGFTCDCVAGFXLNATTNSTCDKDANQDPCASIXNTCSYA-CQNDSGXAVCVCP 177

Query: 1269 DGFMASEDMKTCVDVNECDLNPNICLSGTCENTKGSFICHCDMGYSGKKGK 1319
             GF A    K  V ++   +    C+        G + C C  GY  ++ K
Sbjct: 176  KGF-ALTTTKQAVKISMSAV--RTCVLSLAPIMTGGYTCSCLPGYFLEEDK 33

 Score = 55.1 bits (131), Expect = 4e-07,   Method: Compositional matrix adjust.
 Identities = 54/175 (30%), Positives = 72/175 (41%), Gaps = 8/175 (4%)
 Frame = -1

Query: 1360 GIKCTDLDECSNGTHMCSQHADCKNTMGSYRCLCKDGY---TGDGFTCTDLDECSEXXXX 1416
            G +C D+DEC N    C   A C NT GS+ C C   Y   T D   CTD+DEC+E    
Sbjct: 536  GCQCFDVDECQNSP--CDSVATCTNTDGSFVCSCPTHYRMDTTDMTQCTDIDECAENTDN 363

Query: 1417 XXXXXXXXAPGGYRCECDMGFVPSADGKACEDIDE-----CSLPNICVFGTCHNLPGLFR 1471
                      GG+ C+C  GF  +A   +  D D       S+ N C +  C N  G   
Sbjct: 362  CEQVCNN-TEGGFTCDCVAGFXLNATTNSTCDKDANQDPCASIXNTCSYA-CQNDSGXAV 189

Query: 1472 CECEIGYELDRSGGNCTDVNECLDPTTCISGNCVNTPGSYTCDCPPDFELNPTRV 1526
            C C  G+ L  +          +   TC+        G YTC C P + L   ++
Sbjct: 188  CVCPKGFALTTTKQAVKISMSAV--RTCVLSLAPIMTGGYTCSCLPGYFLEEDKL 30

 Score = 53.1 bits (126), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 50/140 (35%), Positives = 65/140 (46%), Gaps = 6/140 (4%)
 Frame = -1

Query: 514 TCHCRA-GYQSTLTRTECRDIDECLQNGRICNNGRCINTDGSFHCVCNAGFHV-TRDGKN 571
           TC CR  G    +   +C D+DEC QN    +   C NTDGSF C C   + + T D   
Sbjct: 578 TCECRGRGTCDRVRGCQCFDVDEC-QNSPCDSVATCTNTDGSFVCSCPTHYRMDTTDMTQ 402

Query: 572 CEDMDECSIRNMCLNGMCINEDGSFKCICKPGFQL-ASDGRYC-KDINE--CETPGICMN 627
           C D+DEC+        +C N +G F C C  GF L A+    C KD N+  C +     +
Sbjct: 401 CTDIDECAENTDNCEQVCNNTEGGFTCDCVAGFXLNATTNSTCDKDANQDPCASIXNTCS 222

Query: 628 GRCVNTDGSYRCECFPGLAV 647
             C N  G   C C  G A+
Sbjct: 221 YACQNDSGXAVCVCPKGFAL 162

 Score = 52.0 bits (123), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 52/170 (30%), Positives = 72/170 (42%), Gaps = 9/170 (5%)
 Frame = -1

Query: 1322 CTDINECEIGAHNCGRHAVCTNTAGSFKCSCSPGW---IGDGIKCTDLDECSNGTHMCSQ 1378
            C D++EC+     C   A CTNT GSF CSC   +     D  +CTD+DEC+  T  C Q
Sbjct: 527  CFDVDECQNSP--CDSVATCTNTDGSFVCSCPTHYRMDTTDMTQCTDIDECAENTDNCEQ 354

Query: 1379 HADCKNTMGSYRCLCKDGYTGDGFTCT------DLDECSEXXXXXXXXXXXXAPGGYRCE 1432
               C NT G + C C  G+  +  T +      + D C+             + G   C 
Sbjct: 353  V--CNNTEGGFTCDCVAGFXLNATTNSTCDKDANQDPCASIXNTCSYACQNDS-GXAVCV 183

Query: 1433 CDMGFVPSADGKACEDIDECSLPNICVFGTCHNLPGLFRCECEIGYELDR 1482
            C  GF  +   +A +     S    CV      + G + C C  GY L+ 
Sbjct: 182  CPKGFALTTTKQAVK--ISMSAVRTCVLSLAPIMTGGYTCSCLPGYFLEE 39

 Score = 50.4 bits (119), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 45/152 (29%), Positives = 65/152 (42%), Gaps = 7/152 (4%)
 Frame = -1

Query: 465 GRCIPTPGSYRCECNKGFQLDI--RGECIDVDECEKNPCTGGE-CINNQGSYTCHCRAGY 521
             C  T GS+ C C   +++D     +C D+DEC +N     + C N +G +TC C AG+
Sbjct: 482 ATCTNTDGSFVCSCPTHYRMDTTDMTQCTDIDECAENTDNCEQVCNNTEGGFTCDCVAGF 303

Query: 522 QSTLTRTECRDIDE----CLQNGRICNNGRCINTDGSFHCVCNAGFHVTRDGKNCEDMDE 577
               T     D D     C      C+   C N  G   CVC  GF +T   K    +  
Sbjct: 302 XLNATTNSTCDKDANQDPCASIXNTCSYA-CQNDSGXAVCVCPKGFALTT-TKQAVKISM 129

Query: 578 CSIRNMCLNGMCINEDGSFKCICKPGFQLASD 609
            ++R  C+  +     G + C C PG+ L  D
Sbjct: 128 SAVR-TCVLSLAPIMTGGYTCSCLPGYFLEED 36

 Score = 50.1 bits (118), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 51/205 (24%), Positives = 73/205 (35%), Gaps = 9/205 (4%)
 Frame = -1

Query: 2129 DMDECKEPDVCRHGQCINTDGSYRCECPFGYILEGNECVDTDECSVGNPCGNGTCKNVIX 2188
            D+DEC+         C NTDGS+ C CP  Y ++  +                       
Sbjct: 521  DVDECQNSPCDSVATCTNTDGSFVCSCPTHYRMDTTD----------------------- 411

Query: 2189 XXXXXXXXXXXXXXMMTCEDINECAQNPLLCAFRCVNTYGSYECKCPVGYVLREDRRMCK 2248
                          M  C DI+ECA+N   C   C NT G + C C  G+ L        
Sbjct: 410  --------------MTQCTDIDECAENTDNCEQVCNNTEGGFTCDCVAGFXLNATTNSTC 273

Query: 2249 DEDE----CAEGKHDCTEKQMECKNLIGTYMCICGPGYQRRPDGEGCIDENECQTKPGIC 2304
            D+D     CA   + C+     C+N  G  +C+C  G+      +          K  + 
Sbjct: 272  DKDANQDPCASIXNTCS---YACQNDSGXAVCVCPKGFALTTTKQA--------VKISMS 126

Query: 2305 ENGRCLNTL-----GSYTCECNDGF 2324
                C+ +L     G YTC C  G+
Sbjct: 125  AVRTCVLSLAPIMTGGYTCSCLPGY 51

 Score = 48.9 bits (115), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 35/89 (39%), Positives = 43/89 (48%), Gaps = 2/89 (2%)
 Frame = -1

Query: 233 RGFIPNIRTGACQDVDECQAIPGMCQG-GNCINTVGSFECKCPAGHKFNEVSQ-KCEDID 290
           RG    +R   C DVDECQ  P  C     C NT GSF C CP  ++ +     +C DID
Sbjct: 560 RGTCDRVRGCQCFDVDECQNSP--CDSVATCTNTDGSFVCSCPTHYRMDTTDMTQCTDID 387

Query: 291 ECSTIPGVCDGGECTNTVSSYFCKCPPGF 319
           EC+     C+   C NT   + C C  GF
Sbjct: 386 ECAENTDNCE-QVCNNTEGGFTCDCVAGF 303

 Score = 43.9 bits (102), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 37/125 (29%), Positives = 52/125 (41%), Gaps = 4/125 (3%)
 Frame = -1

Query: 724 TDINECALDPDICPNGICENLRGTYKCICNSGYEVDITGKNCVDINE----CVLNSLLCD 779
           TDI+ECA + D C   +C N  G + C C +G+ ++ T  +  D +     C      C 
Sbjct: 398 TDIDECAENTDNCEQ-VCNNTEGGFTCDCVAGFXLNATTNSTCDKDANQDPCASIXNTCS 222

Query: 780 NGQCRNTPGSFVCTCPKGFVYKPDLKTCEDIDECESSPCINGVCKNSPGSFICECSPEST 839
              C+N  G  VC CPKGF      K    I       C+  +     G + C C P   
Sbjct: 221 YA-CQNDSGXAVCVCPKGFALTT-TKQAVKISMSAVRTCVLSLAPIMTGGYTCSCLPGYF 48

Query: 840 LDPTK 844
           L+  K
Sbjct: 47  LEEDK 33

 Score = 43.1 bits (100), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 30/75 (40%), Positives = 37/75 (49%), Gaps = 2/75 (2%)
 Frame = -1

Query: 1608 DIDECQELPGLCQG-GKCINTFGSFQCRCPTGYYLN-EDTRVCDDVNECETPGICGPGTC 1665
            D+DECQ  P  C     C NT GSF C CPT Y ++  D   C D++EC          C
Sbjct: 521  DVDECQNSP--CDSVATCTNTDGSFVCSCPTHYRMDTTDMTQCTDIDECAENTDNCEQVC 348

Query: 1666 YNTVGNYTCICPPDY 1680
             NT G +TC C   +
Sbjct: 347  NNTEGGFTCDCVAGF 303

 Score = 42.7 bits (99), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 58/202 (28%), Positives = 84/202 (41%), Gaps = 10/202 (4%)
 Frame = -1

Query: 904  RIKGTQCEDINECEVFPGVCKN-GLCVNSRGSFKCECPNGMTLDATGRI-CLDIRLETCF 961
            R++G QC D++EC+  P  C +   C N+ GSF C CP    +D T    C DI      
Sbjct: 545  RVRGCQCFDVDECQNSP--CDSVATCTNTDGSFVCSCPTHYRMDTTDMTQCTDI------ 390

Query: 962  LKYDDEECTLPIAGRHRMDACCCSVGAAWGTEECEECPLRNSREYEELCPRGPGFATKDI 1021
                 +EC                   A  T+ CE+  + N+ E    C    GF     
Sbjct: 389  -----DEC-------------------AENTDNCEQ--VCNNTEGGFTCDCVAGFXLNAT 288

Query: 1022 TNGKPFFKDINE--CKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEER----NCTDIDE 1075
            TN     KD N+  C  I + C++  C+N  G   C C  GFAL + ++    + + +  
Sbjct: 287  TNST-CDKDANQDPCASIXNTCSYA-CQNDSGXAVCVCPKGFALTTTKQAVKISMSAVRT 114

Query: 1076 CRIS--PDLCGRGQCVNTPGDF 1095
            C +S  P + G   C   PG F
Sbjct: 113  CVLSLAPIMTGGYTCSCLPGYF 48

 Score = 36.2 bits (82), Expect = 0.18,   Method: Compositional matrix adjust.
 Identities = 28/80 (35%), Positives = 34/80 (42%), Gaps = 4/80 (5%)
 Frame = -1

Query: 244 CQDVDECQAIPGMCQGGNCINTVGSFECKCPAGHKFNEVSQ----KCEDIDECSTIPGVC 299
           C D+DEC      C+   C NT G F C C AG   N  +     K  + D C++I   C
Sbjct: 401 CTDIDECAENTDNCEQV-CNNTEGGFTCDCVAGFXLNATTNSTCDKDANQDPCASIXNTC 225

Query: 300 DGGECTNTVSSYFCKCPPGF 319
               C N      C CP GF
Sbjct: 224 SYA-CQNDSGXAVCVCPKGF 168

 Score = 36.2 bits (82), Expect = 0.19,   Method: Compositional matrix adjust.
 Identities = 30/91 (32%), Positives = 39/91 (42%), Gaps = 1/91 (1%)
 Frame = -1

Query: 2246 MCKDEDECAEGKHDCTEKQMECKNLIGTYMCICGPGYQR-RPDGEGCIDENECQTKPGIC 2304
             C D DEC     D       C N  G+++C C   Y+    D   C D +EC      C
Sbjct: 530  QCFDVDECQNSPCD---SVATCTNTDGSFVCSCPTHYRMDTTDMTQCTDIDECAENTDNC 360

Query: 2305 ENGRCLNTLGSYTCECNDGFTASPTQDECLD 2335
            E   C NT G +TC+C  GF  + T +   D
Sbjct: 359  EQ-VCNNTEGGFTCDCVAGFXLNATTNSTCD 270

 Score = 35.8 bits (81), Expect = 0.24,   Method: Compositional matrix adjust.
 Identities = 58/206 (28%), Positives = 75/206 (36%), Gaps = 3/206 (1%)
 Frame = -1

Query: 2279 GPGYQRRPDGEGCIDENECQTKPGICEN-GRCLNTLGSYTCECNDGFTASPT-QDECLDN 2336
            G G   R  G  C D +ECQ  P  C++   C NT GS+ C C   +    T   +C D 
Sbjct: 563  GRGTCDRVRGCQCFDVDECQNSP--CDSVATCTNTDGSFVCSCPTHYRMDTTDMTQCTDI 390

Query: 2337 REGYCFSEVLQNMCQIGSSNRNPVTKSECCCDGGRGWGPHCEICPFEGTVAYKKLCPHGR 2396
             E           C   + N   V      C+   G G  C+       VA   L     
Sbjct: 389  DE-----------CAENTDNCEQV------CNNTEG-GFTCDC------VAGFXLNATTN 282

Query: 2397 GFMTNGADIDECKVIHDVCRNGECVNDRGSYHCICKTGYTPDITGTACVDLNECNQAPKP 2456
                  A+ D C  I + C    C ND G   C+C  G+    T  A   +     A + 
Sbjct: 281  STCDKDANQDPCASIXNTCSYA-CQNDSGXAVCVCPKGFALTTTKQA---VKISMSAVRT 114

Query: 2457 CNF-ICKNTEGSYQCSCPKGYILQED 2481
            C   +     G Y CSC  GY L+ED
Sbjct: 113  CVLSLAPIMTGGYTCSCLPGYFLEED 36

 Score = 35.8 bits (81), Expect = 0.25,   Method: Compositional matrix adjust.
 Identities = 34/121 (28%), Positives = 51/121 (42%), Gaps = 5/121 (4%)
 Frame = -1

Query: 1565 CCSLGKAWGTPCELCPSVNTSEYKILCPGGEGFRPNPITVIL-EDIDECQELPGLCQGGK 1623
            C  + +   +PC+   +   ++   +C     +R +   +    DIDEC E    C+   
Sbjct: 527  CFDVDECQNSPCDSVATCTNTDGSFVCSCPTHYRMDTTDMTQCTDIDECAENTDNCEQ-V 351

Query: 1624 CINTFGSFQCRCPTGYYLNEDTR-VCD-DVNE--CETPGICGPGTCYNTVGNYTCICPPD 1679
            C NT G F C C  G+ LN  T   CD D N+  C +        C N  G   C+CP  
Sbjct: 350  CNNTEGGFTCDCVAGFXLNATTNSTCDKDANQDPCASIXNTCSYACQNDSGXAVCVCPKG 171

Query: 1680 Y 1680
            +
Sbjct: 170  F 168

 Score = 34.3 bits (77), Expect = 0.68,   Method: Compositional matrix adjust.
 Identities = 40/143 (27%), Positives = 52/143 (36%), Gaps = 4/143 (2%)
 Frame = -1

Query: 1010 CPRGPGFATKDITNGKPFFKDINECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERN 1069
            CP      T D+T       DI+EC      C    C NT G F C C +GF L++   +
Sbjct: 443  CPTHYRMDTTDMTQ----CTDIDECAENTDNCEQ-VCNNTEGGFTCDCVAGFXLNATTNS 279

Query: 1070 CTDIDE----CRISPDLCGRGQCVNTPGDFECKCDEGYESGFMMMKNCMDIDECQRDPLL 1125
              D D     C    + C    C N  G   C C +G+       K  + I         
Sbjct: 278  TCDKDANQDPCASIXNTCSYA-CQNDSGXAVCVCPKGF--ALTTTKQAVKIS--MSAVRT 114

Query: 1126 CRGGICHNTEGSYRCECPPGHQL 1148
            C   +     G Y C C PG+ L
Sbjct: 113  CVLSLAPIMTGGYTCSCLPGYFL 45
>13514
          Length = 1135

 Score = 80.5 bits (197), Expect = 1e-14,   Method: Compositional matrix adjust.
 Identities = 91/249 (36%), Positives = 120/249 (48%), Gaps = 11/249 (4%)
 Frame = -2

Query: 1767 VDIDECREIPGVCENG-VCINMVGSFRCECPVGFFYNDKLLVCEDIDEC--QNGPVCQRN 1823
            ++ID+C  +   C NG  CI++V ++RCECP  +          DIDEC  + G +CQ  
Sbjct: 1077 LNIDDC--VNHRCHNGSTCIDLVENYRCECPPTYT---GEFCDVDIDECDARYGTLCQNG 913

Query: 1824 AECINTAGSYRCDCKPGYRLTSTGQCNDRNECQEIPNICSHG-QCIDTVGSFYCLC---H 1879
            A C NT GS+ C C  G+    TG     NE     N C +G  C D VG FYC C    
Sbjct: 912  ATCHNTDGSFMCVCVNGW----TGDTCTINEDDCAINPCHNGGTCHDRVGYFYCECPQGK 745

Query: 1880 TGFKTNVDQTMCLDINECERDACGNGTCRNTIGSFNCRCNHGFILSHNNDC-IDVDECAT 1938
            TG + ++D     D N C   A    +  N +    C C  G+      DC ID++EC  
Sbjct: 744  TGLRCHLDDA--CDSNPCYASAGCETSPINGVAI--CTCQKGW---RGADCSIDINECQE 586

Query: 1939 GNGNLC--RNGQCVNTVGSFQCRCNEGYEVAPDGRTCVD-INECVLDPGKCAPGTCQNLD 1995
                +     G C N  GS+QC C  G+     GR C + INEC  DP +   GTC +  
Sbjct: 585  STTTVVCEHGGTCQNLNGSYQCNCPTGFT----GRRCENNINECDSDPCQ-NDGTCLDER 421

Query: 1996 GSYRCICPP 2004
            G+YRCIC P
Sbjct: 420  GAYRCICMP 394

 Score = 79.0 bits (193), Expect = 3e-14,   Method: Compositional matrix adjust.
 Identities = 89/263 (33%), Positives = 134/263 (50%), Gaps = 11/263 (4%)
 Frame = -2

Query: 1791 FRCECPVGFFYNDKLLVCEDIDECQNGPVCQRNAECINTAGSYRCDCKPGYRLTSTGQ-C 1849
            + C CP GF   +  L   +ID+C N   C   + CI+   +YRC+C P Y    TG+ C
Sbjct: 1122 YTCTCPSGFRGRNCEL---NIDDCVN-HRCHNGSTCIDLVENYRCECPPTY----TGEFC 967

Query: 1850 N-DRNECQ-EIPNICSHGQ-CIDTVGSFYCLCHTGFKTNVDQTMCLDINECERDACGNG- 1905
            + D +EC      +C +G  C +T GSF C+C  G+  +   T  ++ ++C  + C NG 
Sbjct: 966  DVDIDECDARYGTLCQNGATCHNTDGSFMCVCVNGWTGD---TCTINEDDCAINPCHNGG 796

Query: 1906 TCRNTIGSFNCRCNHGF--ILSHNNDCIDVDECATGNGNLCRNGQCVNTVGSFQCRCNEG 1963
            TC + +G F C C  G   +  H +D  D + C    G  C     +N V    C C +G
Sbjct: 795  TCHDRVGYFYCECPQGKTGLRCHLDDACDSNPCYASAG--CETSP-INGVAI--CTCQKG 631

Query: 1964 YEVAPDGRTCVDINECVLDPGKCA---PGTCQNLDGSYRCICPPGYSLQNDKCE-DIDEC 2019
            +  A      +DINEC            GTCQNL+GSY+C CP G++ +  +CE +I+EC
Sbjct: 630  WRGAD---CSIDINECQESTTTVVCEHGGTCQNLNGSYQCNCPTGFTGR--RCENNINEC 466

Query: 2020 VEEPEICALGTCSNTEGSFKCLC 2042
              +P     GTC +  G+++C+C
Sbjct: 465  DSDP-CQNDGTCLDERGAYRCIC 400

 Score = 71.6 bits (174), Expect = 4e-12,   Method: Compositional matrix adjust.
 Identities = 68/225 (30%), Positives = 106/225 (47%), Gaps = 9/225 (4%)
 Frame = -2

Query: 2465 EGSYQCSCPKGYILQEDGRSCK-DLDECATKQHNCQFLCVNTIGGFTCKCPPGFTQHHTA 2523
            E  Y C+CP G+     GR+C+ ++D+C   + +    C++ +  + C+CPP +T     
Sbjct: 1131 ELDYTCTCPSGF----RGRNCELNIDDCVNHRCHNGSTCIDLVENYRCECPPTYTGEFCD 964

Query: 2524 CIDNNECTSDI-NLCGSKGVCQNTPGSFTCECQRGFSLDQSGASCEDVDECEGNHRCQHG 2582
             +D +EC +    LC +   C NT GSF C C  G++ D       + D+C  N  C +G
Sbjct: 963  -VDIDECDARYGTLCQNGATCHNTDGSFMCVCVNGWTGDTCTI---NEDDCAIN-PCHNG 799

Query: 2583 --CQNIIGGYRCSCPQGYL-QHYQWNQCVDENECLSAHVCGGASCHNTLGSYKCMCPTGF 2639
              C + +G + C CPQG        +   D N C ++  C  +  +   G   C C  G+
Sbjct: 798  GTCHDRVGYFYCECPQGKTGLRCHLDDACDSNPCYASAGCETSPIN---GVAICTCQKGW 628

Query: 2640 QYEQFSGGCQDINEC--GSSQAPCSYG--CSNTEGGYLCGCPPGY 2680
            +    S    DINEC   ++   C +G  C N  G Y C CP G+
Sbjct: 627  RGADCS---IDINECQESTTTVVCEHGGTCQNLNGSYQCNCPTGF 502

 Score = 69.3 bits (168), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 86/274 (31%), Positives = 122/274 (44%), Gaps = 15/274 (5%)
 Frame = -2

Query: 1135 EGSYRCECPPGHQLSPNISACIDINECELSANLCPHGRC------VNLIGKYQCACNPGY 1188
            E  Y C CP G +             CEL+ + C + RC      ++L+  Y+C C    
Sbjct: 1131 ELDYTCTCPSGFRGR----------NCELNIDDCVNHRCHNGSTCIDLVENYRCEC---- 994

Query: 1189 HPTHDRLFC-VDIDECSIMNGG-CE--TFCTNSDGSYECSCQPGFALMPDQRSCT-DIDE 1243
             PT+   FC VDIDEC    G  C+    C N+DGS+ C C  G+       +CT + D+
Sbjct: 993  PPTYTGEFCDVDIDECDARYGTLCQNGATCHNTDGSFMCVCVNGWT----GDTCTINEDD 826

Query: 1244 CEDNPNICDGGQCTNIPGEYRCLCYDGFMASEDMKTCVDVNECDLNPNICLSGTCENT-- 1301
            C  NP   +GG C +  G + C C  G         C   + CD NP    +G CE +  
Sbjct: 825  CAINP-CHNGGTCHDRVGYFYCECPQGKTGLR----CHLDDACDSNPCYASAG-CETSPI 664

Query: 1302 KGSFICHCDMGYSGKKGKTGCTDINECEIGAHN--CGRHAVCTNTAGSFKCSCSPGWIGD 1359
             G  IC C  G+ G        DINEC+       C     C N  GS++C+C  G+ G 
Sbjct: 663  NGVAICTCQKGWRGADCS---IDINECQESTTTVVCEHGGTCQNLNGSYQCNCPTGFTGR 493

Query: 1360 GIKCTDLDECSNGTHMCSQHADCKNTMGSYRCLC 1393
              +  +++EC   +  C     C +  G+YRC+C
Sbjct: 492  RCE-NNINECD--SDPCQNDGTCLDERGAYRCIC 400

 Score = 68.2 bits (165), Expect = 4e-11,   Method: Compositional matrix adjust.
 Identities = 82/279 (29%), Positives = 110/279 (39%), Gaps = 13/279 (4%)
 Frame = -2

Query: 1262 EYRCLCYDGFMASEDMKTCVDVNECDLNPNICLSGTCENTKG------SFICHCDMGYSG 1315
            +Y C C  GF              C+LN + C++  C N         ++ C C   Y+G
Sbjct: 1125 DYTCTCPSGFRGRN----------CELNIDDCVNHRCHNGSTCIDLVENYRCECPPTYTG 976

Query: 1316 KKGKTGCTDINECEIGAHN-CGRHAVCTNTAGSFKCSCSPGWIGDGIKCTDLDECSNGTH 1374
            +       DI+EC+      C   A C NT GSF C C  GW GD   CT ++E     +
Sbjct: 975  EFCDV---DIDECDARYGTLCQNGATCHNTDGSFMCVCVNGWTGD--TCT-INEDDCAIN 814

Query: 1375 MCSQHADCKNTMGSYRCLCKDGYTGDGFTCTDLDECSEXXXXXXXXXXXXAPGGYR-CEC 1433
             C     C + +G + C C  G TG    C   D C                 G   C C
Sbjct: 813  PCHNGGTCHDRVGYFYCECPQGKTG--LRCHLDDACDSNPCYASAGCETSPINGVAICTC 640

Query: 1434 DMGFVPSADGKACE-DIDECSLPNICVF----GTCHNLPGLFRCECEIGYELDRSGGNCT 1488
              G+     G  C  DI+EC      V     GTC NL G ++C C  G+   R   N  
Sbjct: 639  QKGWR----GADCSIDINECQESTTTVVCEHGGTCQNLNGSYQCNCPTGFTGRRCENN-- 478

Query: 1489 DVNECLDPTTCISGNCVNTPGSYTCDCPPDFELNPTRVG 1527
             +NEC        G C++  G+Y C C PD +    R+G
Sbjct: 477  -INECDSDPCQNDGTCLDERGAYRCICMPD*QGQIVRIG 364

 Score = 66.6 bits (161), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 92/298 (30%), Positives = 132/298 (44%), Gaps = 15/298 (5%)
 Frame = -2

Query: 555  FHCVCNAGFHVTRDGKNCE-DMDECSIRNMCLNG-MCINEDGSFKCICKPGFQLASDGRY 612
            + C C +GF     G+NCE ++D+C + + C NG  CI+   +++C C P +     G +
Sbjct: 1122 YTCTCPSGFR----GRNCELNIDDC-VNHRCHNGSTCIDLVENYRCECPPTYT----GEF 970

Query: 613  CK-DINECETP--GICMNGR-CVNTDGSYRCECFPGLAVGLDGRVCVDTHMRSTCYGGYR 668
            C  DI+EC+     +C NG  C NTDGS+ C C  G      G  C  T     C     
Sbjct: 969  CDVDIDECDARYGTLCQNGATCHNTDGSFMCVCVNGWT----GDTC--TINEDDCA---- 820

Query: 669  RGQCVKPLFGAVTKSECCCASTEYAFGEPCQPCPAQNSA---EYQALCSSGPGMTSAGTD 725
                + P     T    C     Y + E    CP   +         C S P   SAG  
Sbjct: 819  ----INPCHNGGT----CHDRVGYFYCE----CPQGKTGLRCHLDDACDSNPCYASAG-- 682

Query: 726  INECALDPDICPNGICENLRGTYKCICNSGYEVDITGKNC-VDINEC--VLNSLLCDNG- 781
               C   P          + G   C C  G+     G +C +DINEC     +++C++G 
Sbjct: 681  ---CETSP----------INGVAICTCQKGWR----GADCSIDINECQESTTTVVCEHGG 553

Query: 782  QCRNTPGSFVCTCPKGFVYKPDLKTCED-IDECESSPCIN-GVCKNSPGSFICECSPE 837
             C+N  GS+ C CP GF      + CE+ I+EC+S PC N G C +  G++ C C P+
Sbjct: 552  TCQNLNGSYQCNCPTGFT----GRRCENNINECDSDPCQNDGTCLDERGAYRCICMPD 391

 Score = 62.8 bits (151), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 68/228 (29%), Positives = 101/228 (44%), Gaps = 44/228 (19%)
 Frame = -2

Query: 1874 FYCLCHTGFKTNVDQTMCLDINECERDACGNG-TCRNTIGSFNCRCNHGFILSHNNDCID 1932
            + C C +GF+    +   L+I++C    C NG TC + + ++ C C   +     +  +D
Sbjct: 1122 YTCTCPSGFRGRNCE---LNIDDCVNHRCHNGSTCIDLVENYRCECPPTYTGEFCD--VD 958

Query: 1933 VDECATGNGNLCRNGQ-CVNTVGSFQCRCNEGYEVAPDGRTC-VDINECVLDPGKCAPGT 1990
            +DEC    G LC+NG  C NT GSF C C  G+     G TC ++ ++C ++P     GT
Sbjct: 957  IDECDARYGTLCQNGATCHNTDGSFMCVCVNGWT----GDTCTINEDDCAINPCH-NGGT 793

Query: 1991 CQNLDGSYRCICPPGYS----LQNDKCE-------------------------------- 2014
            C +  G + C CP G +      +D C+                                
Sbjct: 792  CHDRVGYFYCECPQGKTGLRCHLDDACDSNPCYASAGCETSPINGVAICTCQKGWRGADC 613

Query: 2015 --DIDECVEEPEICAL---GTCSNTEGSFKCLCPEGFSLSSTGRRCQD 2057
              DI+EC E          GTC N  GS++C CP GF    TGRRC++
Sbjct: 612  SIDINECQESTTTVVCEHGGTCQNLNGSYQCNCPTGF----TGRRCEN 481

 Score = 60.5 bits (145), Expect = 9e-09,   Method: Compositional matrix adjust.
 Identities = 71/223 (31%), Positives = 105/223 (47%), Gaps = 18/223 (8%)
 Frame = -2

Query: 1956 FQCRCNEGYEVAPDGRTC-VDINECVLDPGKCAPG-TCQNLDGSYRCICPPGYSLQNDKC 2013
            + C C  G+     GR C ++I++CV    +C  G TC +L  +YRC CPP Y+   + C
Sbjct: 1122 YTCTCPSGFR----GRNCELNIDDCV--NHRCHNGSTCIDLVENYRCECPPTYT--GEFC 967

Query: 2014 E-DIDEC-VEEPEICALG-TCSNTEGSFKCLCPEGFSLSSTGRRCQDLRMS------YCY 2064
            + DIDEC      +C  G TC NT+GSF C+C  G++  +      D  ++       C+
Sbjct: 966  DVDIDECDARYGTLCQNGATCHNTDGSFMCVCVNGWTGDTCTINEDDCAINPCHNGGTCH 787

Query: 2065 AKFEGGKCSSPKSRNHSKQECCCALKGEGWGDPCEL---CPTEPDEAFRQICPFGSGIIV 2121
             +     C  P+ +   +    C L      +PC     C T P      IC    G   
Sbjct: 786  DRVGYFYCECPQGKTGLR----CHLDDACDSNPCYASAGCETSPINGV-AICTCQKGWRG 622

Query: 2122 GPDDSAVDMDECKEPD---VCRH-GQCINTDGSYRCECPFGYI 2160
               D ++D++EC+E     VC H G C N +GSY+C CP G+ 
Sbjct: 621  A--DCSIDINECQESTTTVVCEHGGTCQNLNGSYQCNCPTGFT 499

 Score = 59.3 bits (142), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 67/197 (34%), Positives = 91/197 (46%), Gaps = 11/197 (5%)
 Frame = -2

Query: 458 VRY--LCQNGR-CIPTPGSYRCECNKGFQLDIRGECIDVDECEKNPC-TGGECINNQGSY 513
            RY  LCQNG  C  T GS+ C C  G+  D     I+ D+C  NPC  GG C +  G +
Sbjct: 942 ARYGTLCQNGATCHNTDGSFMCVCVNGWTGDTCT--INEDDCAINPCHNGGTCHDRVGYF 769

Query: 514 TCHCRAGYQSTLTRTECRDIDECLQNGRICNNG-RCINTDGSFHCVCNAGFHVTRDGKNC 572
            C C  G     T   C   D C  N    + G      +G   C C  G+     G +C
Sbjct: 768 YCECPQG----KTGLRCHLDDACDSNPCYASAGCETSPINGVAICTCQKGWR----GADC 613

Query: 573 E-DMDECSIRNMCL----NGMCINEDGSFKCICKPGFQLASDGRYCKD-INECETPGICM 626
             D++EC      +     G C N +GS++C C  GF     GR C++ INEC++     
Sbjct: 612 SIDINECQESTTTVVCEHGGTCQNLNGSYQCNCPTGFT----GRRCENNINECDSDPCQN 445

Query: 627 NGRCVNTDGSYRCECFP 643
           +G C++  G+YRC C P
Sbjct: 444 DGTCLDERGAYRCICMP 394

 Score = 58.5 bits (140), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 75/240 (31%), Positives = 102/240 (42%), Gaps = 8/240 (3%)
 Frame = -2

Query: 1608 DIDECQELPG-LCQ-GGKCINTFGSFQCRCPTGYYLNEDTRVCDD--VNECETPGICGPG 1663
            DIDEC    G LCQ G  C NT GSF C C  G+  +  T   DD  +N C   G     
Sbjct: 960  DIDECDARYGTLCQNGATCHNTDGSFMCVCVNGWTGDTCTINEDDCAINPCHNGG----- 796

Query: 1664 TCYNTVGNYTCICPPDYMQVNGGNNCMDMRRSLCYRNYYADNQTCDGELLFNMTKKMCCC 1723
            TC++ VG + C CP     +             C+ +   D+  C               
Sbjct: 795  TCHDRVGYFYCECPQGKTGLR------------CHLDDACDSNPC--------------- 697

Query: 1724 SYNIGRAWNKPCEQCPIPSTDEFATLCGSQRPGFVIDIYTGLPVDIDECRE--IPGVCEN 1781
                    +  CE  PI        +C  Q+     D      +DI+EC+E     VCE+
Sbjct: 696  ------YASAGCETSPING----VAICTCQKGWRGAD----CSIDINECQESTTTVVCEH 559

Query: 1782 G-VCINMVGSFRCECPVGFFYNDKLLVCE-DIDECQNGPVCQRNAECINTAGSYRCDCKP 1839
            G  C N+ GS++C CP GF        CE +I+EC + P CQ +  C++  G+YRC C P
Sbjct: 558  GGTCQNLNGSYQCNCPTGF----TGRRCENNINECDSDP-CQNDGTCLDERGAYRCICMP 394

 Score = 57.8 bits (138), Expect = 6e-08,   Method: Compositional matrix adjust.
 Identities = 78/260 (30%), Positives = 104/260 (40%), Gaps = 9/260 (3%)
 Frame = -2

Query: 1429 YRCECDMGFVPSADGKACE-DIDECSLP--NICVFG-TCHNLPGLFRCECEIGYELDRSG 1484
            YRCEC     P+  G+ C+ DIDEC      +C  G TCHN  G F C C  G+  D   
Sbjct: 1008 YRCEC----PPTYTGEFCDVDIDECDARYGTLCQNGATCHNTDGSFMCVCVNGWTGDTCT 841

Query: 1485 GNCTD--VNECLDPTTCISGNCVNTPGSYTCDCPPDFELNPTRVGCVDTRSGNCYLDIRP 1542
             N  D  +N C +      G C +  G + C+CP                          
Sbjct: 840  INEDDCAINPCHN-----GGTCHDRVGYFYCECP-------------------------- 754

Query: 1543 RGDNGDTACSNEIGVGVSKASCCCSLGKAWGTPCELCPSVNTSEYKILCPGGEGFRPNPI 1602
                G T     +        C  S G      CE  P    +    +C   +G+R    
Sbjct: 753  ---QGKTGLRCHLDDACDSNPCYASAG------CETSPINGVA----ICTCQKGWRGADC 613

Query: 1603 TVILEDIDECQELPGLC---QGGKCINTFGSFQCRCPTGYYLNEDTRVCDDVNECETPGI 1659
            ++   DI+ECQE         GG C N  GS+QC CPTG+      R  +++NEC++   
Sbjct: 612  SI---DINECQESTTTVVCEHGGTCQNLNGSYQCNCPTGF---TGRRCENNINECDSDPC 451

Query: 1660 CGPGTCYNTVGNYTCICPPD 1679
               GTC +  G Y CIC PD
Sbjct: 450  QNDGTCLDERGAYRCICMPD 391

 Score = 57.0 bits (136), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 80/263 (30%), Positives = 111/263 (42%), Gaps = 20/263 (7%)
 Frame = -2

Query: 2230 YECKCPVGYVLREDRRMCKDEDECAEGKHDCTEKQMECKNLIGTYMCICGPGYQRRPDGE 2289
            Y C CP G+     R    + D+C    H C      C +L+  Y C C P Y     GE
Sbjct: 1122 YTCTCPSGF---RGRNCELNIDDCV--NHRC-HNGSTCIDLVENYRCECPPTYT----GE 973

Query: 2290 GC-IDENECQTKPG-ICENGR-CLNTLGSYTCECNDGFTA---SPTQDECLDN------- 2336
             C +D +EC  + G +C+NG  C NT GS+ C C +G+T    +  +D+C  N       
Sbjct: 972  FCDVDIDECDARYGTLCQNGATCHNTDGSFMCVCVNGWTGDTCTINEDDCAINPCHNGGT 793

Query: 2337 ---REGYCFSEVLQNMCQIGSSNRNPVTKSECCCDGGRGWGPHCEICPFEGTVAYKKLCP 2393
               R GY + E  Q    +     +    + C    G      CE  P  G       C 
Sbjct: 792  CHDRVGYFYCECPQGKTGLRCHLDDACDSNPCYASAG------CETSPINGVAICT--CQ 637

Query: 2394 HGRGFMTNGADIDECK--VIHDVCRNG-ECVNDRGSYHCICKTGYTPDITGTACV-DLNE 2449
             G        DI+EC+      VC +G  C N  GSY C C TG+    TG  C  ++NE
Sbjct: 636  KGWRGADCSIDINECQESTTTVVCEHGGTCQNLNGSYQCNCPTGF----TGRRCENNINE 469

Query: 2450 CNQAPKPCNFICKNTEGSYQCSC 2472
            C+  P   +  C +  G+Y+C C
Sbjct: 468  CDSDPCQNDGTCLDERGAYRCIC 400

 Score = 56.6 bits (135), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 79/231 (34%), Positives = 100/231 (43%), Gaps = 15/231 (6%)
 Frame = -2

Query: 729  CALDPDICPNGICEN------LRGTYKCICNSGYEVDITGKNC-VDINEC-VLNSLLCDN 780
            C L+ D C N  C N      L   Y+C C   Y    TG+ C VDI+EC      LC N
Sbjct: 1083 CELNIDDCVNHRCHNGSTCIDLVENYRCECPPTY----TGEFCDVDIDECDARYGTLCQN 916

Query: 781  GQ-CRNTPGSFVCTCPKGFVYKPDLKTCE-DIDECESSPCING-VCKNSPGSFICECSPE 837
            G  C NT GSF+C C  G+       TC  + D+C  +PC NG  C +  G F CEC   
Sbjct: 915  GATCHNTDGSFMCVCVNGWT----GDTCTINEDDCAINPCHNGGTCHDRVGYFYCECPQG 748

Query: 838  STLDPTKTICIETIKGTCWQTVIDGRCEININGATLKSECCSSLGAAWGSPCTICQLDPI 897
             T                 +  +D  C+ N   A+   E     G A      IC     
Sbjct: 747  KTG---------------LRCHLDDACDSNPCYASAGCETSPINGVA------IC----T 643

Query: 898  CGKGFSRIKGTQCE-DINECE--VFPGVCKNG-LCVNSRGSFKCECPNGMT 944
            C KG+   +G  C  DINEC+      VC++G  C N  GS++C CP G T
Sbjct: 642  CQKGW---RGADCSIDINECQESTTTVVCEHGGTCQNLNGSYQCNCPTGFT 499

 Score = 54.3 bits (129), Expect = 7e-07,   Method: Compositional matrix adjust.
 Identities = 70/205 (34%), Positives = 95/205 (46%), Gaps = 7/205 (3%)
 Frame = -2

Query: 1030 DINECKM-IPSLCTHGK-CRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQ 1087
            DI+EC     +LC +G  C NT GSF C C +G+  D+   N    D+C I+P   G G 
Sbjct: 960  DIDECDARYGTLCQNGATCHNTDGSFMCVCVNGWTGDTCTIN---EDDCAINPCHNG-GT 793

Query: 1088 CVNTPGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRGGICHNT--EGSYRCECPPG 1145
            C +  G F C+C +G ++G      C   D C  +P     G C  +   G   C C  G
Sbjct: 792  CHDRVGYFYCECPQG-KTGLR----CHLDDACDSNPCYASAG-CETSPINGVAICTCQKG 631

Query: 1146 HQLSPNISACIDINECELSAN--LCPHG-RCVNLIGKYQCACNPGYHPTHDRLFCVDIDE 1202
             + +      IDINEC+ S    +C HG  C NL G YQC C  G+     R    +I+E
Sbjct: 630  WRGA---DCSIDINECQESTTTVVCEHGGTCQNLNGSYQCNCPTGFTG---RRCENNINE 469

Query: 1203 CSIMNGGCETFCTNSDGSYECSCQP 1227
            C       +  C +  G+Y C C P
Sbjct: 468  CDSDPCQNDGTCLDERGAYRCICMP 394

 Score = 49.7 bits (117), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 85/263 (32%), Positives = 117/263 (44%), Gaps = 28/263 (10%)
 Frame = -2

Query: 705  NSAEYQALCSSGPGMTSAGTDINECALDPDICPNG-ICENLRGTYKCICNSGYEVDITGK 763
            +  +Y   C SG    +   +I++C      C NG  C +L   Y+C C   Y    TG+
Sbjct: 1134 DELDYTCTCPSGFRGRNCELNIDDCV--NHRCHNGSTCIDLVENYRCECPPTY----TGE 973

Query: 764  NC-VDINEC-VLNSLLCDNGQ-CRNTPGSFVCTCPKGFVYKPDLKTCE-DIDECESSPCI 819
             C VDI+EC      LC NG  C NT GSF+C C  G+       TC  + D+C  +PC 
Sbjct: 972  FCDVDIDECDARYGTLCQNGATCHNTDGSFMCVCVNGWT----GDTCTINEDDCAINPCH 805

Query: 820  NG-VCKNSPGSFICECSPEST-----LDPT-------KTICIET--IKG----TCWQTVI 860
            NG  C +  G F CEC    T     LD          +   ET  I G    TC +   
Sbjct: 804  NGGTCHDRVGYFYCECPQGKTGLRCHLDDACDSNPCYASAGCETSPINGVAICTCQKGWR 625

Query: 861  DGRCEININGATLKSECCSSLGAAWGSPCTICQLDPICG--KGFSRIKGTQCED-INECE 917
               C I+IN      E  +++    G  C        C    GF+   G +CE+ INEC+
Sbjct: 624  GADCSIDINEC---QESTTTVVCEHGGTCQNLNGSYQCNCPTGFT---GRRCENNINECD 463

Query: 918  VFPGVCKN-GLCVNSRGSFKCEC 939
              P  C+N G C++ RG+++C C
Sbjct: 462  SDP--CQNDGTCLDERGAYRCIC 400

 Score = 43.9 bits (102), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 73/252 (28%), Positives = 102/252 (40%), Gaps = 33/252 (13%)
 Frame = -2

Query: 99   MCTCPSGQISPSCGSRSIQHCSIRCMNGGSCSD----DHCLCQKGYIGTHCGQPVCE--- 151
             CTCPSG    +C        + RC NG +C D      C C   Y G  C   + E   
Sbjct: 1119 TCTCPSGFRGRNCELNIDDCVNHRCHNGSTCIDLVENYRCECPPTYTGEFCDVDIDECDA 940

Query: 152  ---SGCLNGGRCVAPN---RCACTYGFTGPQCERD---------YRTGPCFTVVSNQMC- 195
               + C NG  C   +    C C  G+TG  C  +         +  G C   V    C 
Sbjct: 939  RYGTLCQNGATCHNTDGSFMCVCVNGWTGDTCTINEDDCAINPCHNGGTCHDRVGYFYCE 760

Query: 196  --QGQLSGIVCTKTLCCATVGRAWGHPCEMCPAQPHP---CRRGFIPNIRTGACQ-DVDE 249
              QG+ +G+ C     C +        CE  P        C++G+    R   C  D++E
Sbjct: 759  CPQGK-TGLRCHLDDACDSNPCYASAGCETSPINGVAICTCQKGW----RGADCSIDINE 595

Query: 250  CQ--AIPGMCQ-GGNCINTVGSFECKCPAGHKFNEVSQKCE-DIDECSTIPGVCDGGECT 305
            CQ      +C+ GG C N  GS++C CP G       ++CE +I+EC + P   D G C 
Sbjct: 594  CQESTTTVVCEHGGTCQNLNGSYQCNCPTGF----TGRRCENNINECDSDPCQND-GTCL 430

Query: 306  NTVSSYFCKCPP 317
            +   +Y C C P
Sbjct: 429  DERGAYRCICMP 394

 Score = 40.0 bits (92), Expect = 0.014,   Method: Compositional matrix adjust.
 Identities = 75/290 (25%), Positives = 110/290 (37%), Gaps = 7/290 (2%)
 Frame = -2

Query: 1998 YRCICPPGYSLQNDKCE-DIDECVEEPEICALG-TCSNTEGSFKCLCPEGFSLSSTGRRC 2055
            Y C CP G+  +N  CE +ID+CV     C  G TC +   +++C CP  +    TG  C
Sbjct: 1122 YTCTCPSGFRGRN--CELNIDDCVNHR--CHNGSTCIDLVENYRCECPPTY----TGEFC 967

Query: 2056 QDLRMSYCYAKFEGGKCSSPKSRNHSKQECCCALKGEGWGDPCELCPTEPDEAFRQICPF 2115
             D+ +  C A++ G  C +  + +++     C       GD C                 
Sbjct: 966  -DVDIDECDARY-GTLCQNGATCHNTDGSFMCVCVNGWTGDTC----------------- 844

Query: 2116 GSGIIVGPDDSAVDMDECKEPDVCRHGQCINTDGSYRCECPFGYILEGNECVDTDECSVG 2175
                        ++ D+C        G C +  G + CECP G    G  C   D C   
Sbjct: 843  -----------TINEDDCAINPCHNGGTCHDRVGYFYCECPQGKT--GLRCHLDDACD-S 706

Query: 2176 NPC-GNGTCKNVIXXXXXXXXXXXXXXXMMTCEDINECAQNP--LLCAF--RCVNTYGSY 2230
            NPC  +  C+                       DINEC ++   ++C     C N  GSY
Sbjct: 705  NPCYASAGCETSPINGVAICTCQKGWRGADCSIDINECQESTTTVVCEHGGTCQNLNGSY 526

Query: 2231 ECKCPVGYVLREDRRMCKDEDECAEGKHDCTEKQMECKNLIGTYMCICGP 2280
            +C CP G+  R      + E+   E   D  +    C +  G Y CIC P
Sbjct: 525  QCNCPTGFTGR------RCENNINECDSDPCQNDGTCLDERGAYRCICMP 394

 Score = 32.3 bits (72), Expect = 2.8,   Method: Compositional matrix adjust.
 Identities = 23/64 (35%), Positives = 34/64 (53%), Gaps = 1/64 (1%)
 Frame = -2

Query: 465 GRCIPTPGSYRCECNKGFQLDIRGECIDVDECEKNPCTG-GECINNQGSYTCHCRAGYQS 523
           G C    GSY+C C  GF    R E  +++EC+ +PC   G C++ +G+Y C C    Q 
Sbjct: 555 GTCQNLNGSYQCNCPTGF-TGRRCE-NNINECDSDPCQNDGTCLDERGAYRCICMPD*QG 382

Query: 524 TLTR 527
            + R
Sbjct: 381 QIVR 370
>25748
          Length = 425

 Score = 76.6 bits (187), Expect = 1e-13,   Method: Compositional matrix adjust.
 Identities = 48/129 (37%), Positives = 69/129 (53%)
 Frame = +2

Query: 1130 ICHNTEGSYRCECPPGHQLSPNISACIDINECELSANLCPHGRCVNLIGKYQCACNPGYH 1189
             C N EGS+ C CP    L+P+   C  I+ CE     C         G+++C C  GY 
Sbjct: 32   YCTNLEGSFECSCPQHLVLAPDGLNCEAISSCEQRNGGCEQLCVTEPGGEFRCDCYSGYQ 211

Query: 1190 PTHDRLFCVDIDECSIMNGGCETFCTNSDGSYECSCQPGFALMPDQRSCTDIDECEDNPN 1249
             T D + C D++EC  +NGGCE  C N++GSY+C+CQ G+ L    R+  D+ E   +P 
Sbjct: 212  ITSDGVHCEDVNECRELNGGCEQDCYNTEGSYQCACQEGYILRRG-RNNQDVCEAVCDPP 388

Query: 1250 ICDGGQCTN 1258
              + GQC +
Sbjct: 389  CRNNGQCVS 415

 Score = 74.7 bits (182), Expect = 4e-13,   Method: Compositional matrix adjust.
 Identities = 47/115 (40%), Positives = 61/115 (53%), Gaps = 4/115 (3%)
 Frame = +2

Query: 1210 CETFCTNSDGSYECSCQPGFALMPDQRSCTDIDECEDNPNICDGGQCTNIPGEYRCLCYD 1269
            CE +CTN +GS+ECSC     L PD  +C  I  CE     C+    T   GE+RC CY 
Sbjct: 23   CEYYCTNLEGSFECSCPQHLVLAPDGLNCEAISSCEQRNGGCEQLCVTEPGGEFRCDCYS 202

Query: 1270 GFMASEDMKTCVDVNECDLNPNICLSGTCE----NTKGSFICHCDMGYSGKKGKT 1320
            G+  + D   C DVNEC       L+G CE    NT+GS+ C C  GY  ++G+ 
Sbjct: 203  GYQITSDGVHCEDVNECRE-----LNGGCEQDCYNTEGSYQCACQEGYILRRGRN 352

 Score = 72.4 bits (176), Expect = 3e-12,   Method: Compositional matrix adjust.
 Identities = 40/101 (39%), Positives = 54/101 (53%), Gaps = 1/101 (0%)
 Frame = +2

Query: 548 CINTDGSFHCVCNAGFHVTRDGKNCEDMDECSIRNMCLNGMCINE-DGSFKCICKPGFQL 606
           C N +GSF C C     +  DG NCE +  C  RN     +C+ E  G F+C C  G+Q+
Sbjct: 35  CTNLEGSFECSCPQHLVLAPDGLNCEAISSCEQRNGGCEQLCVTEPGGEFRCDCYSGYQI 214

Query: 607 ASDGRYCKDINECETPGICMNGRCVNTDGSYRCECFPGLAV 647
            SDG +C+D+NEC          C NT+GSY+C C  G  +
Sbjct: 215 TSDGVHCEDVNECRELNGGCEQDCYNTEGSYQCACQEGYIL 337

 Score = 68.2 bits (165), Expect = 5e-11,   Method: Compositional matrix adjust.
 Identities = 46/117 (39%), Positives = 65/117 (55%), Gaps = 3/117 (2%)
 Frame = +2

Query: 2457 CNFICKNTEGSYQCSCPKGYILQEDGRSCKDLDECATKQHNCQFLCVNTIGG-FTCKCPP 2515
            C + C N EGS++CSCP+  +L  DG +C+ +  C  +   C+ LCV   GG F C C  
Sbjct: 23   CEYYCTNLEGSFECSCPQHLVLAPDGLNCEAISSCEQRNGGCEQLCVTEPGGEFRCDCYS 202

Query: 2516 GF--TQHHTACIDNNECTSDINLCGSKGVCQNTPGSFTCECQRGFSLDQSGASCEDV 2570
            G+  T     C D NEC  ++N  G +  C NT GS+ C CQ G+ L + G + +DV
Sbjct: 203  GYQITSDGVHCEDVNEC-RELNG-GCEQDCYNTEGSYQCACQEGYIL-RRGRNNQDV 364

 Score = 67.0 bits (162), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 50/132 (37%), Positives = 65/132 (49%), Gaps = 3/132 (2%)
 Frame = +2

Query: 1949 CVNTVGSFQCRCNEGYEVAPDGRTCVDINECVLDPGKCAPGTCQNLDGSYRCICPPGYSL 2008
            C N  GSF+C C +   +APDG  C  I+ C    G C         G +RC C  GY +
Sbjct: 35   CTNLEGSFECSCPQHLVLAPDGLNCEAISSCEQRNGGCEQLCVTEPGGEFRCDCYSGYQI 214

Query: 2009 QND--KCEDIDECVEEPEICALGTCSNTEGSFKCLCPEGFSLSSTGRRCQDLRMSYCYAK 2066
             +D   CED++EC E    C    C NTEGS++C C EG+ L   GR  QD+  + C   
Sbjct: 215  TSDGVHCEDVNECRELNGGCEQ-DCYNTEGSYQCACQEGYILRR-GRNNQDVCEAVCDPP 388

Query: 2067 -FEGGKCSSPKS 2077
                G+C SP  
Sbjct: 389  CRNNGQCVSPNE 424

 Score = 62.0 bits (149), Expect = 4e-09,   Method: Compositional matrix adjust.
 Identities = 41/105 (39%), Positives = 51/105 (48%), Gaps = 6/105 (5%)
 Frame = +2

Query: 1784 CINMVGSFRCECPVGFFYNDKLLVCEDIDECQNGPVCQRNAEC-----INTAGSYRCDCK 1838
            C N+ GSF C CP         L CE I  C+     QRN  C         G +RCDC 
Sbjct: 35   CTNLEGSFECSCPQHLVLAPDGLNCEAISSCE-----QRNGGCEQLCVTEPGGEFRCDCY 199

Query: 1839 PGYRLTSTG-QCNDRNECQEIPNICSHGQCIDTVGSFYCLCHTGF 1882
             GY++TS G  C D NEC+E+   C    C +T GS+ C C  G+
Sbjct: 200  SGYQITSDGVHCEDVNECRELNGGCEQ-DCYNTEGSYQCACQEGY 331

 Score = 58.9 bits (141), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 41/107 (38%), Positives = 51/107 (47%)
 Frame = +2

Query: 2219 CAFRCVNTYGSYECKCPVGYVLREDRRMCKDEDECAEGKHDCTEKQMECKNLIGTYMCIC 2278
            C + C N  GS+EC CP   VL  D   C+    C +    C  +Q+      G + C C
Sbjct: 23   CEYYCTNLEGSFECSCPQHLVLAPDGLNCEAISSCEQRNGGC--EQLCVTEPGGEFRCDC 196

Query: 2279 GPGYQRRPDGEGCIDENECQTKPGICENGRCLNTLGSYTCECNDGFT 2325
              GYQ   DG  C D NEC+   G CE   C NT GSY C C +G+ 
Sbjct: 197  YSGYQITSDGVHCEDVNECRELNGGCEQ-DCYNTEGSYQCACQEGYI 334

 Score = 57.0 bits (136), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 37/100 (37%), Positives = 46/100 (46%), Gaps = 1/100 (1%)
 Frame = +2

Query: 1427 GGYRCECDMGFVPSADGKACEDIDECSLPNICVFGTCHNLPG-LFRCECEIGYELDRSGG 1485
            G + C C    V + DG  CE I  C   N      C   PG  FRC+C  GY++   G 
Sbjct: 50   GSFECSCPQHLVLAPDGLNCEAISSCEQRNGGCEQLCVTEPGGEFRCDCYSGYQITSDGV 229

Query: 1486 NCTDVNECLDPTTCISGNCVNTPGSYTCDCPPDFELNPTR 1525
            +C DVNEC +       +C NT GSY C C   + L   R
Sbjct: 230  HCEDVNECRELNGGCEQDCYNTEGSYQCACQEGYILRRGR 349

 Score = 56.6 bits (135), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 42/128 (32%), Positives = 59/128 (46%), Gaps = 1/128 (0%)
 Frame = +2

Query: 506 CINNQGSYTCHCRAGYQSTLTRTECRDIDECLQNGRICNNGRCINTDGSFHCVCNAGFHV 565
           C N +GS+ C C            C  I  C Q    C         G F C C +G+ +
Sbjct: 35  CTNLEGSFECSCPQHLVLAPDGLNCEAISSCEQRNGGCEQLCVTEPGGEFRCDCYSGYQI 214

Query: 566 TRDGKNCEDMDECSIRNMCLNGMCINEDGSFKCICKPGFQLASDGRYCKDINECETPGIC 625
           T DG +CED++EC   N      C N +GS++C C+ G+ L   GR  +D+ E      C
Sbjct: 215 TSDGVHCEDVNECRELNGGCEQDCYNTEGSYQCACQEGYILRR-GRNNQDVCEAVCDPPC 391

Query: 626 M-NGRCVN 632
             NG+CV+
Sbjct: 392 RNNGQCVS 415

 Score = 56.2 bits (134), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 38/103 (36%), Positives = 49/103 (47%), Gaps = 2/103 (1%)
 Frame = +2

Query: 1298 CENTKGSFICHCDMGYSGKKGKTGCTDINECEIGAHNCGRHAVCTNTAGSFKCSCSPGW- 1356
            C N +GSF C C            C  I+ CE     C +  V T   G F+C C  G+ 
Sbjct: 35   CTNLEGSFECSCPQHLVLAPDGLNCEAISSCEQRNGGCEQLCV-TEPGGEFRCDCYSGYQ 211

Query: 1357 -IGDGIKCTDLDECSNGTHMCSQHADCKNTMGSYRCLCKDGYT 1398
               DG+ C D++EC      C Q  DC NT GSY+C C++GY 
Sbjct: 212  ITSDGVHCEDVNECRELNGGCEQ--DCYNTEGSYQCACQEGYI 334

 Score = 55.1 bits (131), Expect = 4e-07,   Method: Compositional matrix adjust.
 Identities = 39/118 (33%), Positives = 56/118 (47%), Gaps = 3/118 (2%)
 Frame = +2

Query: 2374 GPHCEICPFEGTVAYKKLCPHGRGFMTNGAD---IDECKVIHDVCRNGECVNDRGSYHCI 2430
            G HCE        +++  CP       +G +   I  C+  +  C         G + C 
Sbjct: 14   GDHCEYYCTNLEGSFECSCPQHLVLAPDGLNCEAISSCEQRNGGCEQLCVTEPGGEFRCD 193

Query: 2431 CKTGYTPDITGTACVDLNECNQAPKPCNFICKNTEGSYQCSCPKGYILQEDGRSCKDL 2488
            C +GY     G  C D+NEC +    C   C NTEGSYQC+C +GYIL+  GR+ +D+
Sbjct: 194  CYSGYQITSDGVHCEDVNECRELNGGCEQDCYNTEGSYQCACQEGYILRR-GRNNQDV 364

 Score = 54.7 bits (130), Expect = 6e-07,   Method: Compositional matrix adjust.
 Identities = 42/128 (32%), Positives = 59/128 (46%), Gaps = 3/128 (2%)
 Frame = +2

Query: 1382 CKNTMGSYRCLCKDGYT--GDGFTCTDLDECSEXXXXXXXXXXXXAPGGYRCECDMGFVP 1439
            C N  GS+ C C        DG  C  +  C +              G +RC+C  G+  
Sbjct: 35   CTNLEGSFECSCPQHLVLAPDGLNCEAISSCEQRNGGCEQLCVTEPGGEFRCDCYSGYQI 214

Query: 1440 SADGKACEDIDECSLPNICVFGTCHNLPGLFRCECEIGYELDRSGGNCTDVNECL-DPTT 1498
            ++DG  CED++EC   N      C+N  G ++C C+ GY L R G N  DV E + DP  
Sbjct: 215  TSDGVHCEDVNECRELNGGCEQDCYNTEGSYQCACQEGYIL-RRGRNNQDVCEAVCDPPC 391

Query: 1499 CISGNCVN 1506
              +G CV+
Sbjct: 392  RNNGQCVS 415

 Score = 52.0 bits (123), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 43/129 (33%), Positives = 57/129 (44%), Gaps = 3/129 (2%)
 Frame = +2

Query: 1826 CINTAGSYRCDCKPGYRLTSTG-QCNDRNECQEIPNICSHGQCIDTVGSFYCLCHTGFKT 1884
            C N  GS+ C C     L   G  C   + C++    C      +  G F C C++G++ 
Sbjct: 35   CTNLEGSFECSCPQHLVLAPDGLNCEAISSCEQRNGGCEQLCVTEPGGEFRCDCYSGYQI 214

Query: 1885 NVDQTMCLDINECERDACG-NGTCRNTIGSFNCRCNHGFILSHNNDCIDVDECATGNGNL 1943
              D   C D+NEC     G    C NT GS+ C C  G+IL    +  DV  C       
Sbjct: 215  TSDGVHCEDVNECRELNGGCEQDCYNTEGSYQCACQEGYILRRGRNNQDV--CEAVCDPP 388

Query: 1944 CR-NGQCVN 1951
            CR NGQCV+
Sbjct: 389  CRNNGQCVS 415

 Score = 51.2 bits (121), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 35/109 (32%), Positives = 50/109 (45%), Gaps = 1/109 (0%)
 Frame = +2

Query: 2574 EGNHRCQHGCQNIIGGYRCSCPQGYLQHYQWNQCVDENECLSAHV-CGGASCHNTLGSYK 2632
            +G+H C++ C N+ G + CSCPQ  +       C   + C   +  C         G ++
Sbjct: 11   DGDH-CEYYCTNLEGSFECSCPQHLVLAPDGLNCEAISSCEQRNGGCEQLCVTEPGGEFR 187

Query: 2633 CMCPTGFQYEQFSGGCQDINECGSSQAPCSYGCSNTEGGYLCGCPPGYF 2681
            C C +G+Q       C+D+NEC      C   C NTEG Y C C  GY 
Sbjct: 188  CDCYSGYQITSDGVHCEDVNECRELNGGCEQDCYNTEGSYQCACQEGYI 334

 Score = 50.4 bits (119), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 32/102 (31%), Positives = 44/102 (43%)
 Frame = +2

Query: 1256 CTNIPGEYRCLCYDGFMASEDMKTCVDVNECDLNPNICLSGTCENTKGSFICHCDMGYSG 1315
            CTN+ G + C C    + + D   C  ++ C+     C         G F C C  GY  
Sbjct: 35   CTNLEGSFECSCPQHLVLAPDGLNCEAISSCEQRNGGCEQLCVTEPGGEFRCDCYSGYQI 214

Query: 1316 KKGKTGCTDINECEIGAHNCGRHAVCTNTAGSFKCSCSPGWI 1357
                  C D+NEC     N G    C NT GS++C+C  G+I
Sbjct: 215  TSDGVHCEDVNECR--ELNGGCEQDCYNTEGSYQCACQEGYI 334

 Score = 48.5 bits (114), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 33/97 (34%), Positives = 46/97 (47%)
 Frame = +2

Query: 1601 PITVILEDIDECQELPGLCQGGKCINTFGSFQCRCPTGYYLNEDTRVCDDVNECETPGIC 1660
            P  +  E I  C++  G C+        G F+C C +GY +  D   C+DVNEC      
Sbjct: 92   PDGLNCEAISSCEQRNGGCEQLCVTEPGGEFRCDCYSGYQITSDGVHCEDVNECRELNGG 271

Query: 1661 GPGTCYNTVGNYTCICPPDYMQVNGGNNCMDMRRSLC 1697
                CYNT G+Y C C   Y+   G NN  D+  ++C
Sbjct: 272  CEQDCYNTEGSYQCACQEGYILRRGRNN-QDVCEAVC 379

 Score = 48.1 bits (113), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 43/132 (32%), Positives = 59/132 (44%), Gaps = 1/132 (0%)
 Frame = +2

Query: 2031 CSNTEGSFKCLCPEGFSLSSTGRRCQDLRMSYCYAKFEGGKCSSPKSRNHSKQECCCALK 2090
            C+N EGSF+C CP+   L+  G  C+ +              SS + RN   ++      
Sbjct: 35   CTNLEGSFECSCPQHLVLAPDGLNCEAI--------------SSCEQRNGGCEQ------ 154

Query: 2091 GEGWGDPCELCPTEPDEAFRQICPFGSGIIVGPDDSA-VDMDECKEPDVCRHGQCINTDG 2149
                     LC TEP   FR  C   SG  +  D     D++EC+E +      C NT+G
Sbjct: 155  ---------LCVTEPGGEFR--CDCYSGYQITSDGVHCEDVNECRELNGGCEQDCYNTEG 301

Query: 2150 SYRCECPFGYIL 2161
            SY+C C  GYIL
Sbjct: 302  SYQCACQEGYIL 337

 Score = 47.4 bits (111), Expect = 8e-05,   Method: Compositional matrix adjust.
 Identities = 38/104 (36%), Positives = 51/104 (49%), Gaps = 1/104 (0%)
 Frame = +2

Query: 1046 CRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQCVNTPG-DFECKCDEGYE 1104
            C N  GSF+C C     L  +  NC  I  C      C +  CV  PG +F C C  GY+
Sbjct: 35   CTNLEGSFECSCPQHLVLAPDGLNCEAISSCEQRNGGCEQ-LCVTEPGGEFRCDCYSGYQ 211

Query: 1105 SGFMMMKNCMDIDECQRDPLLCRGGICHNTEGSYRCECPPGHQL 1148
                 + +C D++EC+     C    C+NTEGSY+C C  G+ L
Sbjct: 212  ITSDGV-HCEDVNECRELNGGCEQD-CYNTEGSYQCACQEGYIL 337

 Score = 45.8 bits (107), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 39/119 (32%), Positives = 60/119 (50%), Gaps = 5/119 (4%)
 Frame = +2

Query: 1755 PGFVIDIYTGLPVD-IDECREIPGVCENGVCINMVGSFRCECPVGFFYNDKLLVCEDIDE 1813
            P  ++    GL  + I  C +  G CE        G FRC+C  G+      + CED++E
Sbjct: 71   PQHLVLAPDGLNCEAISSCEQRNGGCEQLCVTEPGGEFRCDCYSGYQITSDGVHCEDVNE 250

Query: 1814 CQ--NGPVCQRNAECINTAGSYRCDCKPGYRLTSTGQCNDRNECQEI--PNICSHGQCI 1868
            C+  NG   Q   +C NT GSY+C C+ GY L      N+++ C+ +  P   ++GQC+
Sbjct: 251  CRELNGGCEQ---DCYNTEGSYQCACQEGYILRRGR--NNQDVCEAVCDPPCRNNGQCV 412

 Score = 44.3 bits (103), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 26/69 (37%), Positives = 39/69 (56%), Gaps = 5/69 (7%)
 Frame = +2

Query: 738 NGICENL-----RGTYKCICNSGYEVDITGKNCVDINECVLNSLLCDNGQCRNTPGSFVC 792
           NG CE L      G ++C C SGY++   G +C D+NEC   +  C+   C NT GS+ C
Sbjct: 137 NGGCEQLCVTEPGGEFRCDCYSGYQITSDGVHCEDVNECRELNGGCEQ-DCYNTEGSYQC 313

Query: 793 TCPKGFVYK 801
            C +G++ +
Sbjct: 314 ACQEGYILR 340

 Score = 42.7 bits (99), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 32/105 (30%), Positives = 46/105 (43%), Gaps = 4/105 (3%)
 Frame = +2

Query: 740 ICENLRGTYKCICNSGYEVDITGKNCVDINECVLNSLLCDNGQCRNTPGSFVCTCPKGFV 799
            C NL G+++C C     +   G NC  I+ C   +  C+        G F C C  G+ 
Sbjct: 32  YCTNLEGSFECSCPQHLVLAPDGLNCEAISSCEQRNGGCEQLCVTEPGGEFRCDCYSGYQ 211

Query: 800 YKPDLKTCEDIDECESSPCINGVCK----NSPGSFICECSPESTL 840
              D   CED++EC     +NG C+    N+ GS+ C C     L
Sbjct: 212 ITSDGVHCEDVNECRE---LNGGCEQDCYNTEGSYQCACQEGYIL 337

 Score = 42.7 bits (99), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 26/72 (36%), Positives = 35/72 (48%), Gaps = 1/72 (1%)
 Frame = +2

Query: 588 MCINEDGSFKCICKPGFQLASDGRYCKDINECETPGICMNGRCVNT-DGSYRCECFPGLA 646
            C N +GSF+C C     LA DG  C+ I+ CE         CV    G +RC+C+ G  
Sbjct: 32  YCTNLEGSFECSCPQHLVLAPDGLNCEAISSCEQRNGGCEQLCVTEPGGEFRCDCYSGYQ 211

Query: 647 VGLDGRVCVDTH 658
           +  DG  C D +
Sbjct: 212 ITSDGVHCEDVN 247

 Score = 42.4 bits (98), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 34/109 (31%), Positives = 45/109 (41%), Gaps = 8/109 (7%)
 Frame = +2

Query: 2144 CINTDGSYRCECPFGYIL--EGNECVDTDECSVGNPCGNGTCKNVIXXXXXXX------X 2195
            C N +GS+ C CP   +L  +G  C     C   N    G C+ +               
Sbjct: 35   CTNLEGSFECSCPQHLVLAPDGLNCEAISSCEQRN----GGCEQLCVTEPGGEFRCDCYS 202

Query: 2196 XXXXXXXMMTCEDINECAQNPLLCAFRCVNTYGSYECKCPVGYVLREDR 2244
                    + CED+NEC +    C   C NT GSY+C C  GY+LR  R
Sbjct: 203  GYQITSDGVHCEDVNECRELNGGCEQDCYNTEGSYQCACQEGYILRRGR 349

 Score = 41.6 bits (96), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 24/76 (31%), Positives = 37/76 (48%)
 Frame = +2

Query: 244 CQDVDECQAIPGMCQGGNCINTVGSFECKCPAGHKFNEVSQKCEDIDECSTIPGVCDGGE 303
           C+ +  C+   G C+        G F C C +G++       CED++EC  + G C+  +
Sbjct: 107 CEAISSCEQRNGGCEQLCVTEPGGEFRCDCYSGYQITSDGVHCEDVNECRELNGGCE-QD 283

Query: 304 CTNTVSSYFCKCPPGF 319
           C NT  SY C C  G+
Sbjct: 284 CYNTEGSYQCACQEGY 331

 Score = 41.6 bits (96), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 32/87 (36%), Positives = 48/87 (55%), Gaps = 3/87 (3%)
 Frame = +2

Query: 467 CIPTPG-SYRCECNKGFQLDIRG-ECIDVDEC-EKNPCTGGECINNQGSYTCHCRAGYQS 523
           C+  PG  +RC+C  G+Q+   G  C DV+EC E N     +C N +GSY C C+ GY  
Sbjct: 158 CVTEPGGEFRCDCYSGYQITSDGVHCEDVNECRELNGGCEQDCYNTEGSYQCACQEGYIL 337

Query: 524 TLTRTECRDIDECLQNGRICNNGRCIN 550
              R   +D+ E + +    NNG+C++
Sbjct: 338 RRGRNN-QDVCEAVCDPPCRNNGQCVS 415

 Score = 40.4 bits (93), Expect = 0.011,   Method: Compositional matrix adjust.
 Identities = 32/108 (29%), Positives = 37/108 (34%)
 Frame = +2

Query: 262 CINTVGSFECKCPAGHKFNEVSQKCEDIDECSTIPGVCDGGECTNTVSSYFCKCPPGFYT 321
           C N  GSFEC CP           CE I  C    G C+    T     + C C  G+  
Sbjct: 35  CTNLEGSFECSCPQHLVLAPDGLNCEAISSCEQRNGGCEQLCVTEPGGEFRCDCYSGYQI 214

Query: 322 SPDGTRCVDVRPGYCYTALANGRCSNQLPQSITKMQCCCDLGRCWSPG 369
           + DG  C DV          NG C      +    QC C  G     G
Sbjct: 215 TSDGVHCEDVNE----CRELNGGCEQDCYNTEGSYQCACQEGYILRRG 346

 Score = 39.7 bits (91), Expect = 0.020,   Method: Compositional matrix adjust.
 Identities = 30/91 (32%), Positives = 43/91 (47%), Gaps = 7/91 (7%)
 Frame = +2

Query: 1007 EELCPRGPG-------FATKDITNGKPFFKDINECKMIPSLCTHGKCRNTIGSFKCRCDS 1059
            E+LC   PG       ++   IT+     +D+NEC+ +   C    C NT GS++C C  
Sbjct: 149  EQLCVTEPGGEFRCDCYSGYQITSDGVHCEDVNECRELNGGCEQ-DCYNTEGSYQCACQE 325

Query: 1060 GFALDSEERNCTDIDECRISPDLCGRGQCVN 1090
            G+ L    RN  D+ E    P     GQCV+
Sbjct: 326  GYIL-RRGRNNQDVCEAVCDPPCRNNGQCVS 415

 Score = 35.8 bits (81), Expect = 0.24,   Method: Compositional matrix adjust.
 Identities = 25/80 (31%), Positives = 40/80 (50%), Gaps = 8/80 (10%)
 Frame = +2

Query: 1757 FVIDIYTGLPV--------DIDECREIPGVCENGVCINMVGSFRCECPVGFFYNDKLLVC 1808
            F  D Y+G  +        D++ECRE+ G CE   C N  GS++C C  G+    +    
Sbjct: 182  FRCDCYSGYQITSDGVHCEDVNECRELNGGCEQD-CYNTEGSYQCACQEGYILR-RGRNN 355

Query: 1809 EDIDECQNGPVCQRNAECIN 1828
            +D+ E    P C+ N +C++
Sbjct: 356  QDVCEAVCDPPCRNNGQCVS 415

 Score = 34.7 bits (78), Expect = 0.50,   Method: Compositional matrix adjust.
 Identities = 37/126 (29%), Positives = 47/126 (37%), Gaps = 3/126 (2%)
 Frame = +2

Query: 823 CKNSPGSFICECSPESTLDPTKTICIETIKGTCWQTVIDGRCE---ININGATLKSECCS 879
           C N  GSF C C     L P    C E I  +C Q   +G CE   +   G   + +C S
Sbjct: 35  CTNLEGSFECSCPQHLVLAPDGLNC-EAIS-SCEQR--NGGCEQLCVTEPGGEFRCDCYS 202

Query: 880 SLGAAWGSPCTICQLDPICGKGFSRIKGTQCEDINECEVFPGVCKNGLCVNSRGSFKCEC 939
                                      G  CED+NEC    G C+   C N+ GS++C C
Sbjct: 203 GYQITS--------------------DGVHCEDVNECRELNGGCEQD-CYNTEGSYQCAC 319

Query: 940 PNGMTL 945
             G  L
Sbjct: 320 QEGYIL 337

 Score = 32.0 bits (71), Expect = 3.6,   Method: Compositional matrix adjust.
 Identities = 22/70 (31%), Positives = 28/70 (40%), Gaps = 1/70 (1%)
 Frame = +2

Query: 1463 CHNLPGLFRCECEIGYELDRSGGNCTDVNECLDPTTCISGNCVNTPG-SYTCDCPPDFEL 1521
            C NL G F C C     L   G NC  ++ C          CV  PG  + CDC   +++
Sbjct: 35   CTNLEGSFECSCPQHLVLAPDGLNCEAISSCEQRNGGCEQLCVTEPGGEFRCDCYSGYQI 214

Query: 1522 NPTRVGCVDT 1531
                V C D 
Sbjct: 215  TSDGVHCEDV 244

 Score = 31.2 bits (69), Expect = 6.5,   Method: Compositional matrix adjust.
 Identities = 21/72 (29%), Positives = 30/72 (41%)
 Frame = +2

Query: 2267 CKNLIGTYMCICGPGYQRRPDGEGCIDENECQTKPGICENGRCLNTLGSYTCECNDGFTA 2326
            C NL G++ C C       PDG  C   + C+ + G CE        G + C+C  G+  
Sbjct: 35   CTNLEGSFECSCPQHLVLAPDGLNCEAISSCEQRNGGCEQLCVTEPGGEFRCDCYSGYQI 214

Query: 2327 SPTQDECLDNRE 2338
            +     C D  E
Sbjct: 215  TSDGVHCEDVNE 250
>14599
          Length = 1135

 Score = 74.3 bits (181), Expect = 6e-13,   Method: Compositional matrix adjust.
 Identities = 42/129 (32%), Positives = 62/129 (48%), Gaps = 4/129 (3%)
 Frame = -2

Query: 1281 VDVNECDLNPNICLSGTCENTKGSFICHCD----MGYSGKKGKTGCTDINECEIGAHNCG 1336
            +   EC+ NP             +F+ H +    + Y+     +  T  + C   +  C 
Sbjct: 480  ISFEECEANPTPLTHTMRLAVSRNFVRHSEKDQVVRYAMSNRVSVMTGTDPCAEASQTCH 301

Query: 1337 RHAVCTNTAGSFKCSCSPGWIGDGIKCTDLDECSNGTHMCSQHADCKNTMGSYRCLCKDG 1396
             HA C  +  SF+C C PG+ G+G  C D+DEC+    +C + A C N  GS++C C  G
Sbjct: 300  AHADCVPSDQSFQCVCRPGYQGNGFDCQDIDECAIEVGVCDEXARCFNVYGSFQCQCMPG 121

Query: 1397 YTGDGFTCT 1405
            Y GDG TCT
Sbjct: 120  YQGDGRTCT 94

 Score = 53.5 bits (127), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 34/81 (41%), Positives = 48/81 (59%), Gaps = 2/81 (2%)
 Frame = -2

Query: 589 CINEDGSFKCICKPGFQLASDGRYCKDINECETP-GIC-MNGRCVNTDGSYRCECFPGLA 646
           C+  D SF+C+C+PG+Q   +G  C+DI+EC    G+C    RC N  GS++C+C PG  
Sbjct: 288 CVPSDQSFQCVCRPGYQ--GNGFDCQDIDECAIEVGVCDEXARCFNVYGSFQCQCMPGYQ 115

Query: 647 VGLDGRVCVDTHMRSTCYGGY 667
              DGR C  T  ++ C G Y
Sbjct: 114 G--DGRTC--TREQTGCGGXY 64

 Score = 52.0 bits (123), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 30/84 (35%), Positives = 45/84 (53%), Gaps = 1/84 (1%)
 Frame = -2

Query: 1364 TDLDECSNGTHMCSQHADCKNTMGSYRCLCKDGYTGDGFTCTDLDECS-EXXXXXXXXXX 1422
            T  D C+  +  C  HADC  +  S++C+C+ GY G+GF C D+DEC+ E          
Sbjct: 342  TGTDPCAEASQTCHAHADCVPSDQSFQCVCRPGYQGNGFDCQDIDECAIEVGVCDEXARC 163

Query: 1423 XXAPGGYRCECDMGFVPSADGKAC 1446
                G ++C+C  G+    DG+ C
Sbjct: 162  FNVYGSFQCQCMPGY--QGDGRTC 97

 Score = 50.4 bits (119), Expect = 9e-06,   Method: Compositional matrix adjust.
 Identities = 52/165 (31%), Positives = 79/165 (47%), Gaps = 12/165 (7%)
 Frame = -2

Query: 489 ECIDVDECEKNP--CTGGECINNQGSYTCHCR----AGYQSTLTRTECRDIDECLQNGRI 542
           + I  +ECE NP   T    +    ++  H        Y  +   +     D C +  + 
Sbjct: 486 QTISFEECEANPTPLTHTMRLAVSRNFVRHSEKDQVVRYAMSNRVSVMTGTDPCAEASQT 307

Query: 543 CN-NGRCINTDGSFHCVCNAGFHVTRDGKNCEDMDECSIR-NMC-LNGMCINEDGSFKCI 599
           C+ +  C+ +D SF CVC  G+    +G +C+D+DEC+I   +C     C N  GSF+C 
Sbjct: 306 CHAHADCVPSDQSFQCVCRPGYQ--GNGFDCQDIDECAIEVGVCDEXARCFNVYGSFQCQ 133

Query: 600 CKPGFQLASDGRYC-KDINECETPGICMNGRCV-NTD-GSYRCEC 641
           C PG+Q   DGR C ++   C       N RCV N++ G  +CEC
Sbjct: 132 CMPGYQ--GDGRTCTREQTGCGGXYCGDNARCVFNSELGQAQCEC 4

 Score = 49.3 bits (116), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 34/97 (35%), Positives = 48/97 (49%), Gaps = 3/97 (3%)
 Frame = -2

Query: 1146 HQLSPNISACIDINECELSANLC-PHGRCVNLIGKYQCACNPGYHPTHDRLFCVDIDECS 1204
            + +S  +S     + C  ++  C  H  CV     +QC C PGY    +   C DIDEC+
Sbjct: 372  YAMSNRVSVMTGTDPCAEASQTCHAHADCVPSDQSFQCVCRPGYQG--NGFDCQDIDECA 199

Query: 1205 IMNGGCE--TFCTNSDGSYECSCQPGFALMPDQRSCT 1239
            I  G C+    C N  GS++C C PG+    D R+CT
Sbjct: 198  IEVGVCDEXARCFNVYGSFQCQCMPGY--QGDGRTCT 94

 Score = 48.9 bits (115), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 30/90 (33%), Positives = 43/90 (47%), Gaps = 1/90 (1%)
 Frame = -2

Query: 2236 VGYVLREDRRMCKDEDECAEGKHDCTEKQMECKNLIGTYMCICGPGYQRRPDGEGCIDEN 2295
            V Y +     +    D CAE    C     +C     ++ C+C PGYQ   +G  C D +
Sbjct: 378  VRYAMSNRVSVMTGTDPCAEASQTC-HAHADCVPSDQSFQCVCRPGYQ--GNGFDCQDID 208

Query: 2296 ECQTKPGIC-ENGRCLNTLGSYTCECNDGF 2324
            EC  + G+C E  RC N  GS+ C+C  G+
Sbjct: 207  ECAIEVGVCDEXARCFNVYGSFQCQCMPGY 118

 Score = 46.2 bits (108), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 28/70 (40%), Positives = 35/70 (50%), Gaps = 1/70 (1%)
 Frame = -2

Query: 1987 APGTCQNLDGSYRCICPPGYSLQNDKCEDIDECVEEPEIC-ALGTCSNTEGSFKCLCPEG 2045
            A   C   D S++C+C PGY      C+DIDEC  E  +C     C N  GSF+C C  G
Sbjct: 300  AHADCVPSDQSFQCVCRPGYQGNGFDCQDIDECAIEVGVCDEXARCFNVYGSFQCQCMPG 121

Query: 2046 FSLSSTGRRC 2055
            +     GR C
Sbjct: 120  Y--QGDGRTC 97

 Score = 45.4 bits (106), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 37/124 (29%), Positives = 56/124 (45%), Gaps = 7/124 (5%)
 Frame = -2

Query: 1031 INECKMIPSLCTH----GKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLC-GR 1085
              EC+  P+  TH       RN +   +      +A+ +     T  D C  +   C   
Sbjct: 474  FEECEANPTPLTHTMRLAVSRNFVRHSEKDQVVRYAMSNRVSVMTGTDPCAEASQTCHAH 295

Query: 1086 GQCVNTPGDFECKCDEGYE-SGFMMMKNCMDIDECQRDPLLC-RGGICHNTEGSYRCECP 1143
              CV +   F+C C  GY+ +GF    +C DIDEC  +  +C     C N  GS++C+C 
Sbjct: 294  ADCVPSDQSFQCVCRPGYQGNGF----DCQDIDECAIEVGVCDEXARCFNVYGSFQCQCM 127

Query: 1144 PGHQ 1147
            PG+Q
Sbjct: 126  PGYQ 115

 Score = 45.4 bits (106), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 29/75 (38%), Positives = 40/75 (53%), Gaps = 1/75 (1%)
 Frame = -2

Query: 1934 DECATGNGNLCRNGQCVNTVGSFQCRCNEGYEVAPDGRTCVDINECVLDPGKC-APGTCQ 1992
            D CA  +     +  CV +  SFQC C  GY+   +G  C DI+EC ++ G C     C 
Sbjct: 333  DPCAEASQTCHAHADCVPSDQSFQCVCRPGYQ--GNGFDCQDIDECAIEVGVCDEXARCF 160

Query: 1993 NLDGSYRCICPPGYS 2007
            N+ GS++C C PGY 
Sbjct: 159  NVYGSFQCQCMPGYQ 115

 Score = 45.1 bits (105), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 28/61 (45%), Positives = 34/61 (55%)
 Frame = -2

Query: 1913 SFNCRCNHGFILSHNNDCIDVDECATGNGNLCRNGQCVNTVGSFQCRCNEGYEVAPDGRT 1972
            SF C C  G+   +  DC D+DECA   G      +C N  GSFQC+C  GY+   DGRT
Sbjct: 270  SFQCVCRPGY-QGNGFDCQDIDECAIEVGVCDEXARCFNVYGSFQCQCMPGYQ--GDGRT 100

Query: 1973 C 1973
            C
Sbjct: 99   C 97

 Score = 44.7 bits (104), Expect = 6e-04,   Method: Compositional matrix adjust.
 Identities = 24/60 (40%), Positives = 34/60 (56%), Gaps = 1/60 (1%)
 Frame = -2

Query: 1131 CHNTEGSYRCECPPGHQLSPNISACIDINECELSANLCPH-GRCVNLIGKYQCACNPGYH 1189
            C  ++ S++C C PG+Q   N   C DI+EC +   +C    RC N+ G +QC C PGY 
Sbjct: 288  CVPSDQSFQCVCRPGYQ--GNGFDCQDIDECAIEVGVCDEXARCFNVYGSFQCQCMPGYQ 115

 Score = 43.9 bits (102), Expect = 8e-04,   Method: Compositional matrix adjust.
 Identities = 32/97 (32%), Positives = 44/97 (45%), Gaps = 2/97 (2%)
 Frame = -2

Query: 240 RTGACQDVDECQAIPGMCQG-GNCINTVGSFECKCPAGHKFNEVSQKCEDIDECSTIPGV 298
           R       D C      C    +C+ +  SF+C C  G++ N     C+DIDEC+   GV
Sbjct: 357 RVSVMTGTDPCAEASQTCHAHADCVPSDQSFQCVCRPGYQGNGFD--CQDIDECAIEVGV 184

Query: 299 CD-GGECTNTVSSYFCKCPPGFYTSPDGTRCVDVRPG 334
           CD    C N   S+ C+C PG+    DG  C   + G
Sbjct: 183 CDEXARCFNVYGSFQCQCMPGY--QGDGRTCTREQTG 79

 Score = 42.0 bits (97), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 29/75 (38%), Positives = 36/75 (48%), Gaps = 2/75 (2%)
 Frame = -2

Query: 1770 DECREIPGVCE-NGVCINMVGSFRCECPVGFFYNDKLLVCEDIDECQ-NGPVCQRNAECI 1827
            D C E    C  +  C+    SF+C C  G  Y      C+DIDEC     VC   A C 
Sbjct: 333  DPCAEASQTCHAHADCVPSDQSFQCVCRPG--YQGNGFDCQDIDECAIEVGVCDEXARCF 160

Query: 1828 NTAGSYRCDCKPGYR 1842
            N  GS++C C PGY+
Sbjct: 159  NVYGSFQCQCMPGYQ 115

 Score = 41.6 bits (96), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 35/134 (26%), Positives = 49/134 (36%), Gaps = 7/134 (5%)
 Frame = -2

Query: 2435 YTPDITGTACVDLNECNQAPKPCNF-----ICKNTEGSYQCSCPKGYILQEDGRSCKDLD 2489
            YT D T    +   EC   P P        + +N     +      Y +          D
Sbjct: 498  YTWDQT----ISFEECEANPTPLTHTMRLAVSRNFVRHSEKDQVVRYAMSNRVSVMTGTD 331

Query: 2490 ECATKQHNCQFL--CVNTIGGFTCKCPPGFTQHHTACIDNNECTSDINLCGSKGVCQNTP 2547
             CA     C     CV +   F C C PG+  +   C D +EC  ++ +C     C N  
Sbjct: 330  PCAEASQTCHAHADCVPSDQSFQCVCRPGYQGNGFDCQDIDECAIEVGVCDEXARCFNVY 151

Query: 2548 GSFTCECQRGFSLD 2561
            GSF C+C  G+  D
Sbjct: 150  GSFQCQCMPGYQGD 109

 Score = 41.6 bits (96), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 25/68 (36%), Positives = 37/68 (54%), Gaps = 1/68 (1%)
 Frame = -2

Query: 1214 CTNSDGSYECSCQPGFALMPDQRSCTDIDECEDNPNICD-GGQCTNIPGEYRCLCYDGFM 1272
            C  SD S++C C+PG+    +   C DIDEC     +CD   +C N+ G ++C C  G+ 
Sbjct: 288  CVPSDQSFQCVCRPGY--QGNGFDCQDIDECAIEVGVCDEXARCFNVYGSFQCQCMPGYQ 115

Query: 1273 ASEDMKTC 1280
               D +TC
Sbjct: 114  G--DGRTC 97

 Score = 40.4 bits (93), Expect = 0.009,   Method: Compositional matrix adjust.
 Identities = 27/71 (38%), Positives = 38/71 (53%), Gaps = 2/71 (2%)
 Frame = -2

Query: 2417 NGECVNDRGSYHCICKTGYTPDITGTACVDLNECNQAPKPCN--FICKNTEGSYQCSCPK 2474
            + +CV    S+ C+C+ GY  +  G  C D++EC      C+    C N  GS+QC C  
Sbjct: 297  HADCVPSDQSFQCVCRPGYQGN--GFDCQDIDECAIEVGVCDEXARCFNVYGSFQCQCMP 124

Query: 2475 GYILQEDGRSC 2485
            GY  Q DGR+C
Sbjct: 123  GY--QGDGRTC 97

 Score = 40.4 bits (93), Expect = 0.010,   Method: Compositional matrix adjust.
 Identities = 37/101 (36%), Positives = 49/101 (48%), Gaps = 2/101 (1%)
 Frame = -2

Query: 2223 CVNTYGSYECKCPVGYVLREDRRMCKDEDECAEGKHDCTEKQMECKNLIGTYMCICGPGY 2282
            CV +  S++C C  GY  + +   C+D DECA     C E    C N+ G++ C C PGY
Sbjct: 288  CVPSDQSFQCVCRPGY--QGNGFDCQDIDECAIEVGVCDEX-ARCFNVYGSFQCQCMPGY 118

Query: 2283 QRRPDGEGCIDENECQTKPGICENGRCL--NTLGSYTCECN 2321
            Q   DG  C  E          +N RC+  + LG   CECN
Sbjct: 117  Q--GDGRTCTREQTGCGGXYCGDNARCVFNSELGQAQCECN 1

 Score = 40.0 bits (92), Expect = 0.014,   Method: Compositional matrix adjust.
 Identities = 28/104 (26%), Positives = 49/104 (47%), Gaps = 2/104 (1%)
 Frame = -2

Query: 1782 GVCINMVGSFRCECPVGFFYNDKLLVCEDIDEC-QNGPVCQRNAECINTAGSYRCDCKPG 1840
             V  N V     +  V +  ++++ V    D C +    C  +A+C+ +  S++C C+PG
Sbjct: 423  AVSRNFVRHSEKDQVVRYAMSNRVSVMTGTDPCAEASQTCHAHADCVPSDQSFQCVCRPG 244

Query: 1841 YRLTSTGQCNDRNECQEIPNICSH-GQCIDTVGSFYCLCHTGFK 1883
            Y+      C D +EC     +C    +C +  GSF C C  G++
Sbjct: 243  YQGNGF-DCQDIDECAIEVGVCDEXARCFNVYGSFQCQCMPGYQ 115

 Score = 39.7 bits (91), Expect = 0.016,   Method: Compositional matrix adjust.
 Identities = 24/62 (38%), Positives = 37/62 (59%), Gaps = 1/62 (1%)
 Frame = -2

Query: 747 TYKCICNSGYEVDITGKNCVDINECVLNSLLCDN-GQCRNTPGSFVCTCPKGFVYKPDLK 805
           +++C+C  GY+ +  G +C DI+EC +   +CD   +C N  GSF C C  G  Y+ D +
Sbjct: 270 SFQCVCRPGYQGN--GFDCQDIDECAIEVGVCDEXARCFNVYGSFQCQCMPG--YQGDGR 103

Query: 806 TC 807
           TC
Sbjct: 102 TC 97

 Score = 37.7 bits (86), Expect = 0.069,   Method: Compositional matrix adjust.
 Identities = 36/148 (24%), Positives = 54/148 (36%)
 Frame = -2

Query: 2103 TEPDEAFRQICPFGSGIIVGPDDSAVDMDECKEPDVCRHGQCINTDGSYRCECPFGYILE 2162
            +E D+  R        ++ G D  A     C       H  C+ +D S++C C  GY   
Sbjct: 396  SEKDQVVRYAMSNRVSVMTGTDPCAEASQTCHA-----HADCVPSDQSFQCVCRPGYQGN 232

Query: 2163 GNECVDTDECSVGNPCGNGTCKNVIXXXXXXXXXXXXXXXMMTCEDINECAQNPLLCAFR 2222
            G +C D DEC++                                 ++  C +       R
Sbjct: 231  GFDCQDIDECAI---------------------------------EVGVCDEXA-----R 166

Query: 2223 CVNTYGSYECKCPVGYVLREDRRMCKDE 2250
            C N YGS++C+C  GY  + D R C  E
Sbjct: 165  CFNVYGSFQCQCMPGY--QGDGRTCTRE 88

 Score = 37.0 bits (84), Expect = 0.12,   Method: Compositional matrix adjust.
 Identities = 17/34 (50%), Positives = 23/34 (67%), Gaps = 1/34 (2%)
 Frame = -2

Query: 1607 EDIDECQELPGLC-QGGKCINTFGSFQCRCPTGY 1639
            +DIDEC    G+C +  +C N +GSFQC+C  GY
Sbjct: 219  QDIDECAIEVGVCDEXARCFNVYGSFQCQCMPGY 118

 Score = 37.0 bits (84), Expect = 0.12,   Method: Compositional matrix adjust.
 Identities = 37/100 (37%), Positives = 51/100 (51%), Gaps = 6/100 (6%)
 Frame = -2

Query: 467 CIPTPGSYRCECNKGFQLDIRGECIDVDEC--EKNPC-TGGECINNQGSYTCHCRAGYQS 523
           C+P+  S++C C  G+Q +   +C D+DEC  E   C     C N  GS+ C C  GYQ 
Sbjct: 288 CVPSDQSFQCVCRPGYQGN-GFDCQDIDECAIEVGVCDEXARCFNVYGSFQCQCMPGYQG 112

Query: 524 TLTRTECRDIDECLQNGRIC-NNGRCI-NTD-GSFHCVCN 560
              RT  R+   C   G  C +N RC+ N++ G   C CN
Sbjct: 111 D-GRTCTREQTGC--GGXYCGDNARCVFNSELGQAQCECN 1

 Score = 35.8 bits (81), Expect = 0.24,   Method: Compositional matrix adjust.
 Identities = 26/76 (34%), Positives = 36/76 (47%), Gaps = 2/76 (2%)
 Frame = -2

Query: 2607 CVDENECLSAHVCGGASCHNTLGSYKCMCPTGFQYEQFSGGCQDINECGSSQAPCSYG-- 2664
            C + ++   AH    A C  +  S++C+C  G+Q   F   CQDI+EC      C     
Sbjct: 327  CAEASQTCHAH----ADCVPSDQSFQCVCRPGYQGNGFD--CQDIDECAIEVGVCDEXAR 166

Query: 2665 CSNTEGGYLCGCPPGY 2680
            C N  G + C C PGY
Sbjct: 165  CFNVYGSFQCQCMPGY 118

 Score = 35.4 bits (80), Expect = 0.32,   Method: Compositional matrix adjust.
 Identities = 26/79 (32%), Positives = 36/79 (45%), Gaps = 3/79 (3%)
 Frame = -2

Query: 1605 ILEDIDECQELPGLCQG-GKCINTFGSFQCRCPTGYYLNEDTRVCDDVNECETP-GICGP 1662
            ++   D C E    C     C+ +  SFQC C  GY  N     C D++EC    G+C  
Sbjct: 348  VMTGTDPCAEASQTCHAHADCVPSDQSFQCVCRPGYQGNGFD--CQDIDECAIEVGVCDE 175

Query: 1663 -GTCYNTVGNYTCICPPDY 1680
               C+N  G++ C C P Y
Sbjct: 174  XARCFNVYGSFQCQCMPGY 118

 Score = 35.0 bits (79), Expect = 0.49,   Method: Compositional matrix adjust.
 Identities = 21/47 (44%), Positives = 27/47 (57%), Gaps = 1/47 (2%)
 Frame = -2

Query: 907 GTQCEDINECEVFPGVC-KNGLCVNSRGSFKCECPNGMTLDATGRIC 952
           G  C+DI+EC +  GVC +   C N  GSF+C+C  G   D  GR C
Sbjct: 231 GFDCQDIDECAIEVGVCDEXARCFNVYGSFQCQCMPGYQGD--GRTC 97

 Score = 32.7 bits (73), Expect = 2.3,   Method: Compositional matrix adjust.
 Identities = 35/134 (26%), Positives = 53/134 (39%), Gaps = 9/134 (6%)
 Frame = -2

Query: 1229 FALMPDQRSCTDIDECEDNPNICDG-GQCTNIPGEYRCLCYDGFMASEDMKTCVDVNECD 1287
            +A+       T  D C +    C     C      ++C+C  G+  +     C D++EC 
Sbjct: 372  YAMSNRVSVMTGTDPCAEASQTCHAHADCVPSDQSFQCVCRPGYQGNG--FDCQDIDECA 199

Query: 1288 LNPNIC-LSGTCENTKGSFICHCDMGYSG-----KKGKTGCTDINECEIGAHNCGRHAVC 1341
            +   +C     C N  GSF C C  GY G      + +TGC        G   CG +A C
Sbjct: 198  IEVGVCDEXARCFNVYGSFQCQCMPGYQGDGRTCTREQTGC--------GGXYCGDNARC 43

Query: 1342 T--NTAGSFKCSCS 1353
               +  G  +C C+
Sbjct: 42   VFNSELGQAQCECN 1

 Score = 30.8 bits (68), Expect = 7.8,   Method: Compositional matrix adjust.
 Identities = 31/102 (30%), Positives = 43/102 (42%), Gaps = 19/102 (18%)
 Frame = -2

Query: 695 GEPCQPCPAQ-----NSAEYQALCSSGPGMTSAG---TDINECALDPDICPN-GICENLR 745
            E  Q C A      +   +Q +C   PG    G    DI+ECA++  +C     C N+ 
Sbjct: 324 AEASQTCHAHADCVPSDQSFQCVCR--PGYQGNGFDCQDIDECAIEVGVCDEXARCFNVY 151

Query: 746 GTYKCICNSGYEVDIT----------GKNCVDINECVLNSLL 777
           G+++C C  GY+ D            G  C D   CV NS L
Sbjct: 150 GSFQCQCMPGYQGDGRTCTREQTGCGGXYCGDNARCVFNSEL 25
>07364
          Length = 985

 Score = 70.1 bits (170), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 44/105 (41%), Positives = 57/105 (54%), Gaps = 2/105 (1%)
 Frame = -1

Query: 77  GNQCIVPICRHSCGDG-FCSRPNMCTCPSGQISPSCGSRSIQHCSIRCMNGGSC-SDDHC 134
           G  C  P C   C +G +C+   +C CP G     C      +C   C NGG C   D C
Sbjct: 940 GLSCETPHCDPPCLNGGYCTMTAVCACPYGYTGVDCQP----YCHKTCHNGGQCIRHDRC 773

Query: 135 LCQKGYIGTHCGQPVCESGCLNGGRCVAPNRCACTYGFTGPQCER 179
            C KGY G +C  PVC  GC+NGG+CVAP RC+C  G+ G +C++
Sbjct: 772 RCAKGYKGRYCETPVCGRGCVNGGKCVAPRRCSCPSGYRGRRCQK 638

 Score = 49.3 bits (116), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 40/107 (37%), Positives = 52/107 (48%), Gaps = 3/107 (2%)
 Frame = -1

Query: 77  GNQCIVPICRHSCGDG-FCSRPNMCTCPSGQISPSCGSRSIQHCSIRCMNGGSC-SDDHC 134
           G +C  P CR SC +G  C  P +C CP   + P C   +   C  +C NGG C ++  C
Sbjct: 655 GRRCQKPRCRPSCKNGGKCIAPGICLCPPSLLGPRCRRHT---CRKKCRNGGRCVANGKC 485

Query: 135 LCQKGYIGTHCGQPVCESGCLNGGRCVAPNRCACT-YGFTGPQCERD 180
           LC   + G +C +  C   CLNGGRC           GF G +CER 
Sbjct: 484 LCPPSFYGRYCHRAKCNLTCLNGGRCRRRKNRCRCPKGFRGRRCERR 344

 Score = 38.9 bits (89), Expect = 0.028,   Method: Compositional matrix adjust.
 Identities = 21/49 (42%), Positives = 25/49 (51%)
 Frame = -1

Query: 130 SDDHCLCQKGYIGTHCGQPVCESGCLNGGRCVAPNRCACTYGFTGPQCE 178
           S   C C   + G  C  P C+  CLNGG C     CAC YG+TG  C+
Sbjct: 976 SPGLCHCPHNFTGLSCETPHCDPPCLNGGYCTMTAVCACPYGYTGVDCQ 830
>12576
          Length = 1682

 Score = 49.7 bits (117), Expect(2) = 7e-11,   Method: Compositional matrix adjust.
 Identities = 83/323 (25%), Positives = 122/323 (37%), Gaps = 26/323 (8%)
 Frame = -1

Query: 522  QSTLTRTECRDIDECLQNGRICNNGRCINTDGSFHCVCNAGFHVTRDGKNCEDMDECSIR 581
            Q  +   +  D    LQ     N GRC     SF CVC  G+    +G  C  + +    
Sbjct: 1478 QWXILWIQLPDCSRPLQPNPCRNGGRCNRNGASFSCVCVGGY----NGLTCASLSDPCNP 1311

Query: 582  NMCLN-GMCINEDGSFKCICKPGFQLASDGRYCKDINECETPGICMNGRCVNTD---GSY 637
            N C N G+C  E    K + K       +G  C+ + +   P  C NG   +T    G+ 
Sbjct: 1310 NPCRNGGVCSTEVSGGKLVSKCYCANGYEGNTCQTLADPCKPNPCKNGGLCSTTVVGGAL 1131

Query: 638  RCECFPGLAVGLDGRVCVDTHMRSTCYGGYRRGQCVKPLFGAVTKSECCCASTEYA---- 693
              +CF   + G DG+ C   +   +       G+C     G      C C +        
Sbjct: 1130 TFKCF--CSAGYDGKTCTGLNDPCSSNPCRNGGRCSSVAQGGALTFSCXCINGYTGXDCS 957

Query: 694  -FGEPCQPCPAQN---------SAEYQALCSSGPGMTSA--GTDINECALDPDICPNGI- 740
               +PC   P +N         +    A C   PG T A    + N C+  P  C NG  
Sbjct: 956  QTADPCSSKPCKNGGMCKNVVQNGALVAACVCAPGFTGATCSQENNPCSSRP--CKNGAT 783

Query: 741  ----CENLRGTYKCICNSGYEVDITGKNCVDINECVLNSLLCDNGQCRNTP-GSFVCTCP 795
                      T+KC C SGY  +   +  VD++    +S   +   C+ T  GS+ C CP
Sbjct: 782  CSPQLTRSSATFKCXCKSGYSGETCDQK-VDLSGACKSSPCLNGASCKPTAYGSYKCACP 606

Query: 796  KGFVYKPDLKTCEDIDECESSPC 818
               +Y+ D   CE   E  ++PC
Sbjct: 605  A--LYQGD--NCEIKSEWVNAPC 549

 Score = 37.7 bits (86), Expect(2) = 7e-11,   Method: Compositional matrix adjust.
 Identities = 28/63 (44%), Positives = 31/63 (49%), Gaps = 3/63 (4%)
 Frame = -2

Query: 462  CQNG-RCIPTPGSYRCECNKGFQLDIRGECID-VDECEKNPCT-GGECINNQGSYTCHCR 518
            CQNG +C P  GS+ C C  GF       C    + C  NPC  GG C  N  SYTC C 
Sbjct: 1645 CQNGGQCQPNGGSFTCSCVNGFS---GVNCASRPNPCGSNPCANGGRCNANGASYTCSCS 1475

Query: 519  AGY 521
             GY
Sbjct: 1474 GGY 1466

 Score = 34.7 bits (78), Expect(2) = 5e-05,   Method: Compositional matrix adjust.
 Identities = 32/93 (34%), Positives = 43/93 (46%), Gaps = 1/93 (1%)
 Frame = -2

Query: 1279 TCVDVNECDLNPNICLSG-TCENTKGSFICHCDMGYSGKKGKTGCTDINECEIGAHNCGR 1337
            +C  +  CD NP  C +G  C+   GSF C C  G+SG       +  N C  G++ C  
Sbjct: 1681 SCTPITACDSNP--CQNGGQCQPNGGSFTCSCVNGFSGVNCA---SRPNPC--GSNPCAN 1523

Query: 1338 HAVCTNTAGSFKCSCSPGWIGDGIKCTDLDECS 1370
               C     S+ CSCS G+ G   + T  D CS
Sbjct: 1522 GGRCNANGASYTCSCSGGYYGFNCQ-TAPDPCS 1427

 Score = 32.3 bits (72), Expect(2) = 5e-05,   Method: Compositional matrix adjust.
 Identities = 71/302 (23%), Positives = 106/302 (35%), Gaps = 38/302 (12%)
 Frame = -1

Query: 1376 CSQHADCKNTMGSYRCLCKDGYTGDGFTCTDL-DECSEXXXXXXXXXXXXAPGGY---RC 1431
            C     C     S+ C+C  GY  +G TC  L D C+               GG    +C
Sbjct: 1418 CRNGGRCNRNGASFSCVCVGGY--NGLTCASLSDPCNPNPCRNGGVCSTEVSGGKLVSKC 1245

Query: 1432 ECDMGFVPSADGKACEDIDECSLPNICVFG-----TCHNLPGLFRCECEIGYELDRSGGN 1486
             C  G+    +G  C+ + +   PN C  G     T       F+C C  GY+    G  
Sbjct: 1244 YCANGY----EGNTCQTLADPCKPNPCKNGGLCSTTVVGGALTFKCFCSAGYD----GKT 1089

Query: 1487 CTDVNECLDPTTCISG---NCVNTPGSYTCDCPPDFELNPTRVGCVDTRSG-NCYLDIRP 1542
            CT +N+      C +G   + V   G+ T  C            C++  +G +C     P
Sbjct: 1088 CTGLNDPCSSNPCRNGGRCSSVAQGGALTFSC-----------XCINGYTGXDCSQTADP 942

Query: 1543 ---RGDNGDTACSNEIGVGVSKASCCCSLGKAWGT-----------PCE----LCPSVNT 1584
               +       C N +  G   A+C C+ G    T           PC+      P +  
Sbjct: 941  CSSKPCKNGGMCKNVVQNGALVAACVCAPGFTGATCSQENNPCSSRPCKNGATCSPQLTR 762

Query: 1585 SEYKILCPGGEGFRPNPITVILEDIDECQELPGLCQGGKCIN-------TFGSFQCRCPT 1637
            S     C    G+         E  D+  +L G C+   C+N        +GS++C CP 
Sbjct: 761  SSATFKCXCKSGYSG-------ETCDQKVDLSGACKSSPCLNGASCKPTAYGSYKCACPA 603

Query: 1638 GY 1639
             Y
Sbjct: 602  LY 597

 Score = 42.0 bits (97), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 98/386 (25%), Positives = 149/386 (38%), Gaps = 37/386 (9%)
 Frame = -1

Query: 2300 KPGICENG-RCLNTLGSYTCEC---NDGFTASPTQDECLDNREGYCFSEVLQNMCQIGSS 2355
            +P  C NG RC     S++C C    +G T +   D C                      
Sbjct: 1430 QPNPCRNGGRCNRNGASFSCVCVGGYNGLTCASLSDPC---------------------- 1317

Query: 2356 NRNPVTKSECCCDGGRGWGPHCEICPFEGTVAYKKLCPHGRGFMTNGADIDECKVIHDVC 2415
            N NP      C +GG        +C  E  V+  KL    + +  NG + + C+ + D C
Sbjct: 1316 NPNP------CRNGG--------VCSTE--VSGGKL--VSKCYCANGYEGNTCQTLADPC 1191

Query: 2416 RNGEC----------VNDRGSYHCICKTGYTPDITGTACVDLNE-CNQAP----KPCNFI 2460
            +   C          V    ++ C C  GY     G  C  LN+ C+  P      C+ +
Sbjct: 1190 KPNPCKNGGLCSTTVVGGALTFKCFCSAGY----DGKTCTGLNDPCSSNPCRNGGRCSSV 1023

Query: 2461 CKNTEGSYQCSCPKGYILQEDGRSC-KDLDECATKQHNCQFLCVNTI--GGFT--CKCPP 2515
             +    ++ C C  GY     G  C +  D C++K      +C N +  G     C C P
Sbjct: 1022 AQGGALTFSCXCINGYT----GXDCSQTADPCSSKPCKNGGMCKNVVQNGALVAACVCAP 855

Query: 2516 GFTQHHTACIDNNECTSDINLCGSKGVCQ----NTPGSFTCECQRGFSLDQSGASCEDVD 2571
            GFT   T   +NN C+S    C +   C      +  +F C C+ G+    SG +C+   
Sbjct: 854  GFT-GATCSQENNPCSS--RPCKNGATCSPQLTRSSATFKCXCKSGY----SGETCDQKV 696

Query: 2572 ECEG---NHRCQHGCQ---NIIGGYRCSCPQGYLQHYQWNQCVDENECLSAHVCGGASC- 2624
            +  G   +  C +G        G Y+C+CP      YQ + C  ++E ++A     A C 
Sbjct: 695  DLSGACKSSPCLNGASCKPTAYGSYKCACP----ALYQGDNCEIKSEWVNAPCGBTAGCT 528

Query: 2625 -HNTL-GSYKCMCPTGFQYEQFSGGC 2648
              NT+    KC+C  G+ Y   S  C
Sbjct: 527  GENTVCFKGKCLCTPGYYYSVSSQKC 450

 Score = 41.2 bits (95), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 85/305 (27%), Positives = 129/305 (42%), Gaps = 32/305 (10%)
 Frame = -1

Query: 1248 PNIC-DGGQCTNIPGEYRCLCYDGFMASEDMKTCVDVNECDLNPNICLSG---TCENTKG 1303
            PN C +GG+C      + C+C  G+    +  TC  +++   NPN C +G   + E + G
Sbjct: 1427 PNPCRNGGRCNRNGASFSCVCVGGY----NGLTCASLSD-PCNPNPCRNGGVCSTEVSGG 1263

Query: 1304 SFI--CHCDMGYSGKKGKTGCTDINECEIGAHNCGRHAVCTNT----AGSFKCSCSPGWI 1357
              +  C+C  GY   +G T  T  + C+   + C    +C+ T    A +FKC CS G+ 
Sbjct: 1262 KLVSKCYCANGY---EGNTCQTLADPCK--PNPCKNGGLCSTTVVGGALTFKCFCSAGY- 1101

Query: 1358 GDGIKCTDLDE------CSNGTHMCSQHADCKNTMGSYRCLCKDGYTGDGFTCTDLDECS 1411
             DG  CT L++      C NG   CS  A  +    ++ C C +GYTG   + T  D CS
Sbjct: 1100 -DGKTCTGLNDPCSSNPCRNGGR-CSSVA--QGGALTFSCXCINGYTGXDCSQT-ADPCS 936

Query: 1412 EXXXXXXXXXXXXAPGG---YRCECDMGFVPSA--------DGKACEDIDECSLPNICVF 1460
                            G     C C  GF  +           + C++   CS P +   
Sbjct: 935  SKPCKNGGMCKNVVQNGALVAACVCAPGFTGATCSQENNPCSSRPCKNGATCS-PQL--- 768

Query: 1461 GTCHNLPGLFRCECEIGYELDRSGGNC---TDVNECLDPTTCISG-NCVNTP-GSYTCDC 1515
                     F+C C+ GY    SG  C    D++     + C++G +C  T  GSY C C
Sbjct: 767  ---TRSSATFKCXCKSGY----SGETCDQKVDLSGACKSSPCLNGASCKPTAYGSYKCAC 609

Query: 1516 PPDFE 1520
            P  ++
Sbjct: 608  PALYQ 594

 Score = 40.8 bits (94), Expect = 0.009,   Method: Compositional matrix adjust.
 Identities = 68/260 (26%), Positives = 94/260 (36%), Gaps = 49/260 (18%)
 Frame = -1

Query: 123  CMNGGSCSDD--------HCLCQKGYIGTHC---GQPVCESGCLNGGRCVAPNR------ 165
            C NGG CS           C C  GY G  C     P   + C NGGRC +  +      
Sbjct: 1178 CKNGGLCSTTVVGGALTFKCFCSAGYDGKTCTGLNDPCSSNPCRNGGRCSSVAQGGALTF 999

Query: 166  -CACTYGFTGPQCERDY---------RTGPCFTVVSNQMCQGQLSGIVCTKTLCCATVGR 215
             C C  G+TG  C +             G C  VV N      ++  VC      AT  +
Sbjct: 998  SCXCINGYTGXDCSQTADPCSSKPCKNGGMCKNVVQNGA---LVAACVCAPGFTGATCSQ 828

Query: 216  AWGHPCEMCPAQPHPCRRGFI--PNI-RTGAC-----------QDVDECQAIPGMCQGGN 261
                  E  P    PC+ G    P + R+ A            +  D+   + G C+   
Sbjct: 827  ------ENNPCSSRPCKNGATCSPQLTRSSATFKCXCKSGYSGETCDQKVDLSGACKSSP 666

Query: 262  CIN-------TVGSFECKCPAGHKFNEVSQKCEDIDECSTIPGVCDGGECTNTV-SSYFC 313
            C+N         GS++C CPA ++ +    K E ++        C G    NTV     C
Sbjct: 665  CLNGASCKPTAYGSYKCACPALYQGDNCEIKSEWVNAPCGBTAGCTG---ENTVCFKGKC 495

Query: 314  KCPPGFYTSPDGTRCVDVRP 333
             C PG+Y S    +C+   P
Sbjct: 494  LCTPGYYYSVSSQKCIKSCP 435

 Score = 38.9 bits (89), Expect = 0.030,   Method: Compositional matrix adjust.
 Identities = 30/93 (32%), Positives = 41/93 (44%), Gaps = 2/93 (2%)
 Frame = -2

Query: 489  ECIDVDECEKNPC-TGGECINNQGSYTCHCRAGYQSTLTRTECRDIDECLQNGRICNNGR 547
             C  +  C+ NPC  GG+C  N GS+TC C  G+        C        +    N GR
Sbjct: 1681 SCTPITACDSNPCQNGGQCQPNGGSFTCSCVNGFSGV----NCASRPNPCGSNPCANGGR 1514

Query: 548  CINTDGSFHCVCNAGFHVTRDGKNCEDM-DECS 579
            C     S+ C C+ G++    G NC+   D CS
Sbjct: 1513 CNANGASYTCSCSGGYY----GFNCQTAPDPCS 1427

 Score = 37.4 bits (85), Expect = 0.093,   Method: Compositional matrix adjust.
 Identities = 71/266 (26%), Positives = 107/266 (40%), Gaps = 30/266 (11%)
 Frame = -1

Query: 1812 DECQNGPVCQRNAECINTAGSYRCDCKPGYRLTSTGQCNDRNECQEIPNICSHGQCIDTV 1871
            + C+NG  C RN        S+ C C  GY   +    +D       PN C +G    T 
Sbjct: 1424 NPCRNGGRCNRNG------ASFSCVCVGGYNGLTCASLSDPCN----PNPCRNGGVCSTE 1275

Query: 1872 GS-----FYCLCHTGFKTNVDQTMCLDINECERDACGN-GTCRNTIG----SFNCRCNHG 1921
             S       C C  G++ N  QT+    + C+ + C N G C  T+     +F C C+ G
Sbjct: 1274 VSGGKLVSKCYCANGYEGNTCQTL---ADPCKPNPCKNGGLCSTTVVGGALTFKCFCSAG 1104

Query: 1922 FILSHNNDCIDV-DECATGNGNLCRNGQCVNTVG-----SFQCRCNEGYEVAPDGRTCVD 1975
            +       C  + D C++   N CRNG   ++V      +F C C  GY      +T   
Sbjct: 1103 Y---DGKTCTGLNDPCSS---NPCRNGGRCSSVAQGGALTFSCXCINGYTGXDCSQT--- 951

Query: 1976 INECVLDPGKCAPGTCQNL--DGSY--RCICPPGYSLQNDKCEDIDECVEEPEICALGTC 2031
             + C   P K   G C+N+  +G+    C+C PG++           C +E   C+   C
Sbjct: 950  ADPCSSKPCK-NGGMCKNVVQNGALVAACVCAPGFTGA--------TCSQENNPCSSRPC 798

Query: 2032 SN----------TEGSFKCLCPEGFS 2047
             N          +  +FKC C  G+S
Sbjct: 797  KNGATCSPQLTRSSATFKCXCKSGYS 720

 Score = 30.0 bits (66), Expect(2) = 0.19,   Method: Compositional matrix adjust.
 Identities = 48/164 (29%), Positives = 67/164 (40%), Gaps = 13/164 (7%)
 Frame = -1

Query: 1288 LNPNICLSG-TCENTKGSFICHCDMGYSGKKGKTGCTDINECEIGAHNCGRHAVCTN--T 1344
            L PN C +G  C     SF C C  GY+G      C  +++     + C    VC+   +
Sbjct: 1433 LQPNPCRNGGRCNRNGASFSCVCVGGYNGLT----CASLSD-PCNPNPCRNGGVCSTEVS 1269

Query: 1345 AGSF--KCSCSPGWIGDGIKCTDLDECSNGTHMCSQHADCKNTMG----SYRCLCKDGYT 1398
             G    KC C+ G+ G+  + T  D C    + C     C  T+     +++C C  GY 
Sbjct: 1268 GGKLVSKCYCANGYEGNTCQ-TLADPCK--PNPCKNGGLCSTTVVGGALTFKCFCSAGY- 1101

Query: 1399 GDGFTCTDL-DECSEXXXXXXXXXXXXAPGG---YRCECDMGFV 1438
             DG TCT L D CS             A GG   + C C  G+ 
Sbjct: 1100 -DGKTCTGLNDPCSSNPCRNGGRCSSVAQGGALTFSCXCINGYT 972

 Score = 24.6 bits (52), Expect(2) = 0.19,   Method: Compositional matrix adjust.
 Identities = 19/64 (29%), Positives = 26/64 (40%), Gaps = 6/64 (9%)
 Frame = -2

Query: 1214 CTNSDGSYECSCQPGFALMPDQRSCTDIDECEDNPNIC------DGGQCTNIPGEYRCLC 1267
            C  + GS+ CSC  GF+ +           C   PN C      +GG+C      Y C C
Sbjct: 1627 CQPNGGSFTCSCVNGFSGV----------NCASRPNPCGSNPCANGGRCNANGASYTCSC 1478

Query: 1268 YDGF 1271
              G+
Sbjct: 1477 SGGY 1466

 Score = 35.4 bits (80), Expect = 0.33,   Method: Compositional matrix adjust.
 Identities = 28/79 (35%), Positives = 34/79 (43%)
 Frame = -2

Query: 1237 SCTDIDECEDNPNICDGGQCTNIPGEYRCLCYDGFMASEDMKTCVDVNECDLNPNICLSG 1296
            SCT I  C+ NP   +GGQC    G + C C +GF     +      N C  NP     G
Sbjct: 1681 SCTPITACDSNP-CQNGGQCQPNGGSFTCSCVNGF---SGVNCASRPNPCGSNP-CANGG 1517

Query: 1297 TCENTKGSFICHCDMGYSG 1315
             C     S+ C C  GY G
Sbjct: 1516 RCNANGASYTCSCSGGYYG 1460

 Score = 35.0 bits (79), Expect = 0.45,   Method: Compositional matrix adjust.
 Identities = 27/68 (39%), Positives = 32/68 (47%), Gaps = 2/68 (2%)
 Frame = -2

Query: 2533 DINLCGSKGVCQNTPGSFTCECQRGFSLDQSGASCEDVDECEGNHRCQHG--CQNIIGGY 2590
            D N C + G CQ   GSFTC C  GF    SG +C       G++ C +G  C      Y
Sbjct: 1657 DSNPCQNGGQCQPNGGSFTCSCVNGF----SGVNCASRPNPCGSNPCANGGRCNANGASY 1490

Query: 2591 RCSCPQGY 2598
             CSC  GY
Sbjct: 1489 TCSCSGGY 1466

 Score = 31.2 bits (69), Expect = 5.7,   Method: Compositional matrix adjust.
 Identities = 30/89 (33%), Positives = 39/89 (43%), Gaps = 10/89 (11%)
 Frame = -2

Query: 1891 CLDINECERDACGNG-TCRNTIGSFNCRCNHGFI----LSHNNDCIDVDECATGNGNLCR 1945
            C  I  C+ + C NG  C+   GSF C C +GF      S  N C   + CA G      
Sbjct: 1678 CTPITACDSNPCQNGGQCQPNGGSFTCSCVNGFSGVNCASRPNPC-GSNPCANG------ 1520

Query: 1946 NGQCVNTVGSFQCRCNEGY-----EVAPD 1969
             G+C     S+ C C+ GY     + APD
Sbjct: 1519 -GRCNANGASYTCSCSGGYYGFNCQTAPD 1436

 Score = 31.2 bits (69), Expect = 6.8,   Method: Compositional matrix adjust.
 Identities = 27/74 (36%), Positives = 36/74 (48%), Gaps = 2/74 (2%)
 Frame = -2

Query: 764  NCVDINECVLNSLLCDNG-QCRNTPGSFVCTCPKGFVYKPDLKTCEDIDECESSPCIN-G 821
            +C  I  C  +S  C NG QC+   GSF C+C  GF     +      + C S+PC N G
Sbjct: 1681 SCTPITAC--DSNPCQNGGQCQPNGGSFTCSCVNGFS---GVNCASRPNPCGSNPCANGG 1517

Query: 822  VCKNSPGSFICECS 835
             C  +  S+ C CS
Sbjct: 1516 RCNANGASYTCSCS 1475
>30893
          Length = 490

 Score = 61.2 bits (147), Expect = 6e-09,   Method: Compositional matrix adjust.
 Identities = 50/137 (36%), Positives = 66/137 (48%), Gaps = 2/137 (1%)
 Frame = +2

Query: 1044 GKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQ-CVNTPGDFECKCDEG 1102
            G C NT  +  C C SGF     E    DI+EC  +P  C  G  C +  G + C C+ G
Sbjct: 119  GTCHNTGNTHMCTCASGFEGSYCEN---DINECFSAP--CQNGATCTDLIGRYTCTCEPG 283

Query: 1103 YESGFMMMKNC-MDIDECQRDPLLCRGGICHNTEGSYRCECPPGHQLSPNISACIDINEC 1161
            Y+       NC  DIDEC   P L  GG CH+   +Y+C CPPG Q    +   +D N+C
Sbjct: 284  YQG-----LNCEYDIDECHNQPCL-NGGTCHDLVNTYKCSCPPGTQ---GLLCEMDENDC 436

Query: 1162 ELSANLCPHGRCVNLIG 1178
               +     G CV+ +G
Sbjct: 437  LFDSTCHNGGTCVDKVG 487

 Score = 53.9 bits (128), Expect = 8e-07,   Method: Compositional matrix adjust.
 Identities = 43/114 (37%), Positives = 61/114 (53%), Gaps = 4/114 (3%)
 Frame = +2

Query: 2531 TSDINLCGSKGVCQNTPGSFTCECQRGFSLDQSGASCE-DVDECEGNHRCQHG--CQNII 2587
             S+ +LC + G C NT  +  C C  GF     G+ CE D++EC  +  CQ+G  C ++I
Sbjct: 89   VSEQDLCQNGGTCHNTGNTHMCTCASGFE----GSYCENDINECF-SAPCQNGATCTDLI 253

Query: 2588 GGYRCSCPQGYLQHYQWNQC-VDENECLSAHVCGGASCHNTLGSYKCMCPTGFQ 2640
            G Y C+C  GY    Q   C  D +EC +     G +CH+ + +YKC CP G Q
Sbjct: 254  GRYTCTCEPGY----QGLNCEYDIDECHNQPCLNGGTCHDLVNTYKCSCPPGTQ 403

 Score = 52.8 bits (125), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 46/142 (32%), Positives = 64/142 (45%), Gaps = 8/142 (5%)
 Frame = +2

Query: 1095 FECKCDEGYESGFMMMKN-----CMDIDECQRDPLLCRGGICHNTEGSYRCECPPGHQLS 1149
            + C C +G+      +++        +       L   GG CHNT  ++ C C  G + S
Sbjct: 2    YRCNCSQGWTGALCDVQSVSCSVAASVRGVSEQDLCQNGGTCHNTGNTHMCTCASGFEGS 181

Query: 1150 PNISACIDINECELSANLCPHGRCVNLIGKYQCACNPGYHPTHDRLFCVDIDECS---IM 1206
               +   DINEC  SA       C +LIG+Y C C PGY   +      DIDEC     +
Sbjct: 182  YCEN---DINEC-FSAPCQNGATCTDLIGRYTCTCEPGYQGLNCEY---DIDECHNQPCL 340

Query: 1207 NGGCETFCTNSDGSYECSCQPG 1228
            NGG    C +   +Y+CSC PG
Sbjct: 341  NGG---TCHDLVNTYKCSCPPG 397

 Score = 52.4 bits (124), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 43/109 (39%), Positives = 55/109 (50%), Gaps = 4/109 (3%)
 Frame = +2

Query: 732 DPDICPNG-ICENLRGTYKCICNSGYEVDITGKNCV-DINECVLNSLLCDNGQ-CRNTPG 788
           + D+C NG  C N   T+ C C SG+E    G  C  DINEC   S  C NG  C +  G
Sbjct: 95  EQDLCQNGGTCHNTGNTHMCTCASGFE----GSYCENDINECF--SAPCQNGATCTDLIG 256

Query: 789 SFVCTCPKGFVYKPDLKTCEDIDECESSPCIN-GVCKNSPGSFICECSP 836
            + CTC  G+     L    DIDEC + PC+N G C +   ++ C C P
Sbjct: 257 RYTCTCEPGY---QGLNCEYDIDECHNQPCLNGGTCHDLVNTYKCSCPP 394

 Score = 50.8 bits (120), Expect = 8e-06,   Method: Compositional matrix adjust.
 Identities = 52/143 (36%), Positives = 73/143 (51%), Gaps = 4/143 (2%)
 Frame = +2

Query: 1898 ERDACGNG-TCRNTIGSFNCRCNHGFILSHNNDCIDVDECATGNGNLCRNGQ-CVNTVGS 1955
            E+D C NG TC NT  +  C C  GF  S+  +  D++EC +     C+NG  C + +G 
Sbjct: 95   EQDLCQNGGTCHNTGNTHMCTCASGFEGSYCEN--DINECFSA---PCQNGATCTDLIGR 259

Query: 1956 FQCRCNEGYEVAPDGRTC-VDINECVLDPGKCAPGTCQNLDGSYRCICPPGYSLQNDKCE 2014
            + C C  GY+    G  C  DI+EC   P     GTC +L  +Y+C CPPG   Q   CE
Sbjct: 260  YTCTCEPGYQ----GLNCEYDIDECHNQPCL-NGGTCHDLVNTYKCSCPPG--TQGLLCE 418

Query: 2015 -DIDECVEEPEICALGTCSNTEG 2036
             D ++C+ +      GTC +  G
Sbjct: 419  MDENDCLFDSTCHNGGTCVDKVG 487

 Score = 50.4 bits (119), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 47/147 (31%), Positives = 65/147 (44%), Gaps = 10/147 (6%)
 Frame = +2

Query: 1263 YRCLCYDGFMAS---------EDMKTCVDVNECDLNPNICLSGTCENTKGSFICHCDMGY 1313
            YRC C  G+  +             +   V+E DL  N    GTC NT  + +C C  G+
Sbjct: 2    YRCNCSQGWTGALCDVQSVSCSVAASVRGVSEQDLCQN---GGTCHNTGNTHMCTCASGF 172

Query: 1314 SGKKGKTGCTDINECEIGAHNCGRHAVCTNTAGSFKCSCSPGWIGDGIKCT-DLDECSNG 1372
             G   +    DINEC      C   A CT+  G + C+C PG+   G+ C  D+DEC N 
Sbjct: 173  EGSYCEN---DINECFSAP--CQNGATCTDLIGRYTCTCEPGY--QGLNCEYDIDECHN- 328

Query: 1373 THMCSQHADCKNTMGSYRCLCKDGYTG 1399
               C     C + + +Y+C C  G  G
Sbjct: 329  -QPCLNGGTCHDLVNTYKCSCPPGTQG 406

 Score = 48.5 bits (114), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 46/140 (32%), Positives = 69/140 (49%), Gaps = 3/140 (2%)
 Frame = +2

Query: 2412 HDVCRNGECVNDRGSYH-CICKTGYTPDITGTACV-DLNECNQAPKPCNFICKNTEGSYQ 2469
             D+C+NG   ++ G+ H C C +G+     G+ C  D+NEC  AP      C +  G Y 
Sbjct: 98   QDLCQNGGTCHNTGNTHMCTCASGFE----GSYCENDINECFSAPCQNGATCTDLIGRYT 265

Query: 2470 CSCPKGYILQEDGRSCK-DLDECATKQHNCQFLCVNTIGGFTCKCPPGFTQHHTACIDNN 2528
            C+C  GY     G +C+ D+DEC  +       C + +  + C CPPG TQ     +D N
Sbjct: 266  CTCEPGY----QGLNCEYDIDECHNQPCLNGGTCHDLVNTYKCSCPPG-TQGLLCEMDEN 430

Query: 2529 ECTSDINLCGSKGVCQNTPG 2548
            +C  D + C + G C +  G
Sbjct: 431  DCLFD-STCHNGGTCVDKVG 487

 Score = 47.8 bits (112), Expect = 6e-05,   Method: Compositional matrix adjust.
 Identities = 49/141 (34%), Positives = 67/141 (47%), Gaps = 6/141 (4%)
 Frame = +2

Query: 544 NNGRCINTDGSFHCVCNAGFHVTRDGKNCE-DMDECSIRNMCLNGM-CINEDGSFKCICK 601
           N G C NT  +  C C +GF    +G  CE D++EC     C NG  C +  G + C C+
Sbjct: 113 NGGTCHNTGNTHMCTCASGF----EGSYCENDINEC-FSAPCQNGATCTDLIGRYTCTCE 277

Query: 602 PGFQLASDGRYCK-DINECETPGICMNGRCVNTDGSYRCECFP---GLAVGLDGRVCVDT 657
           PG+Q    G  C+ DI+EC        G C +   +Y+C C P   GL   +D   C+  
Sbjct: 278 PGYQ----GLNCEYDIDECHNQPCLNGGTCHDLVNTYKCSCPPGTQGLLCEMDENDCL-- 439

Query: 658 HMRSTCYGGYRRGQCVKPLFG 678
              STC+ G   G CV  + G
Sbjct: 440 -FDSTCHNG---GTCVDKVGG 490

 Score = 47.8 bits (112), Expect = 7e-05,   Method: Compositional matrix adjust.
 Identities = 55/168 (32%), Positives = 78/168 (46%), Gaps = 13/168 (7%)
 Frame = +2

Query: 474 YRCECNKGFQ---LDIRGECIDVDEC-----EKNPC-TGGECINNQGSYTCHCRAGYQST 524
           YRC C++G+     D++     V        E++ C  GG C N   ++ C C +G++ +
Sbjct: 2   YRCNCSQGWTGALCDVQSVSCSVAASVRGVSEQDLCQNGGTCHNTGNTHMCTCASGFEGS 181

Query: 525 LTRTECRDIDECLQNGRICNNGR-CINTDGSFHCVCNAGFHVTRDGKNCE-DMDECSIRN 582
                  DI+EC      C NG  C +  G + C C  G+     G NCE D+DEC    
Sbjct: 182 YCE---NDINECFS--APCQNGATCTDLIGRYTCTCEPGYQ----GLNCEYDIDECH-NQ 331

Query: 583 MCLNG-MCINEDGSFKCICKPGFQLASDGRYCK-DINECETPGICMNG 628
            CLNG  C +   ++KC C PG Q    G  C+ D N+C     C NG
Sbjct: 332 PCLNGGTCHDLVNTYKCSCPPGTQ----GLLCEMDENDCLFDSTCHNG 463

 Score = 46.6 bits (109), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 46/140 (32%), Positives = 66/140 (47%), Gaps = 5/140 (3%)
 Frame = +2

Query: 1778 VCENG-VCINMVGSFRCECPVGFFYNDKLLVCE-DIDECQNGPVCQRNAECINTAGSYRC 1835
            +C+NG  C N   +  C C  GF    +   CE DI+EC + P CQ  A C +  G Y C
Sbjct: 104  LCQNGGTCHNTGNTHMCTCASGF----EGSYCENDINECFSAP-CQNGATCTDLIGRYTC 268

Query: 1836 DCKPGYRLTSTGQCNDRNECQEIPNICSHGQCIDTVGSFYCLC---HTGFKTNVDQTMCL 1892
             C+PGY+  +     D +EC   P + + G C D V ++ C C     G    +D+  CL
Sbjct: 269  TCEPGYQGLNCEY--DIDECHNQPCL-NGGTCHDLVNTYKCSCPPGTQGLLCEMDENDCL 439

Query: 1893 DINECERDACGNGTCRNTIG 1912
              + C       GTC + +G
Sbjct: 440  FDSTCHN----GGTCVDKVG 487

 Score = 46.2 bits (108), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 46/140 (32%), Positives = 60/140 (42%), Gaps = 10/140 (7%)
 Frame = +2

Query: 2550 FTCECQRGFS---LDQSGASCEDVDECEG---NHRCQHG--CQNIIGGYRCSCPQGYLQH 2601
            + C C +G++    D    SC       G      CQ+G  C N    + C+C  G+   
Sbjct: 2    YRCNCSQGWTGALCDVQSVSCSVAASVRGVSEQDLCQNGGTCHNTGNTHMCTCASGFEGS 181

Query: 2602 YQWNQCVDENECLSAHVCGGASCHNTLGSYKCMCPTGFQYEQFSGGCQDINECGSSQAPC 2661
            Y  N   D NEC SA    GA+C + +G Y C C  G+Q         DI+EC     PC
Sbjct: 182  YCEN---DINECFSAPCQNGATCTDLIGRYTCTCEPGYQGLNCE---YDIDEC--HNQPC 337

Query: 2662 SYG--CSNTEGGYLCGCPPG 2679
              G  C +    Y C CPPG
Sbjct: 338  LNGGTCHDLVNTYKCSCPPG 397

 Score = 45.1 bits (105), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 51/172 (29%), Positives = 74/172 (43%), Gaps = 10/172 (5%)
 Frame = +2

Query: 1348 FKCSCSPGWIG-----DGIKCTDLDECSNGTH--MCSQHADCKNTMGSYRCLCKDGYTGD 1400
            ++C+CS GW G       + C+        +   +C     C NT  ++ C C  G+ G 
Sbjct: 2    YRCNCSQGWTGALCDVQSVSCSVAASVRGVSEQDLCQNGGTCHNTGNTHMCTCASGFEGS 181

Query: 1401 GFTCTDLDECSEXXXXXXXXXXXXAPGGYRCECDMGFVPSADGKACE-DIDECSLPNICV 1459
             +   D++EC                G Y C C+ G+     G  CE DIDEC       
Sbjct: 182  -YCENDINECFSAPCQNGATCTDLI-GRYTCTCEPGY----QGLNCEYDIDECHNQPCLN 343

Query: 1460 FGTCHNLPGLFRCECEIGYELDRSGGNC-TDVNECLDPTTCIS-GNCVNTPG 1509
             GTCH+L   ++C C  G +    G  C  D N+CL  +TC + G CV+  G
Sbjct: 344  GGTCHDLVNTYKCSCPPGTQ----GLLCEMDENDCLFDSTCHNGGTCVDKVG 487

 Score = 44.7 bits (104), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 48/138 (34%), Positives = 63/138 (45%), Gaps = 4/138 (2%)
 Frame = +2

Query: 461 LCQNG-RCIPTPGSYRCECNKGFQLDIRGECIDVDECEKNPC-TGGECINNQGSYTCHCR 518
           LCQNG  C  T  ++ C C  GF+        D++EC   PC  G  C +  G YTC C 
Sbjct: 104 LCQNGGTCHNTGNTHMCTCASGFEGSYCEN--DINECFSAPCQNGATCTDLIGRYTCTCE 277

Query: 519 AGYQSTLTRTECRDIDECLQNGRICNNGRCINTDGSFHCVCNAGFHVTRDGKNCE-DMDE 577
            GYQ         DIDEC  N    N G C +   ++ C C  G      G  CE D ++
Sbjct: 278 PGYQGLNCE---YDIDEC-HNQPCLNGGTCHDLVNTYKCSCPPG----TQGLLCEMDEND 433

Query: 578 CSIRNMCLN-GMCINEDG 594
           C   + C N G C+++ G
Sbjct: 434 CLFDSTCHNGGTCVDKVG 487

 Score = 44.7 bits (104), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 49/156 (31%), Positives = 69/156 (44%), Gaps = 2/156 (1%)
 Frame = +2

Query: 165 RCACTYGFTGPQCERDYRTGPCFTVVSNQMCQGQLSGIVCTKTLCCATVGRAWGHPCEMC 224
           RC C+ G+TG  C  D ++  C    S    +G     +C     C   G        MC
Sbjct: 5   RCNCSQGWTGALC--DVQSVSCSVAAS---VRGVSEQDLCQNGGTCHNTGNT-----HMC 154

Query: 225 PAQPHPCRRGFIPNIRTGACQDVDECQAIPGMCQ-GGNCINTVGSFECKCPAGHKFNEVS 283
                 C  GF  +       D++EC + P  CQ G  C + +G + C C  G++     
Sbjct: 155 T-----CASGFEGSYCE---NDINECFSAP--CQNGATCTDLIGRYTCTCEPGYQ----G 292

Query: 284 QKCE-DIDECSTIPGVCDGGECTNTVSSYFCKCPPG 318
             CE DIDEC   P + +GG C + V++Y C CPPG
Sbjct: 293 LNCEYDIDECHNQPCL-NGGTCHDLVNTYKCSCPPG 397

 Score = 41.6 bits (96), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 35/100 (35%), Positives = 47/100 (47%), Gaps = 9/100 (9%)
 Frame = +2

Query: 2590 YRCSCPQGY------LQHYQWNQCVDENECLSAHVC-GGASCHNTLGSYKCMCPTGFQYE 2642
            YRC+C QG+      +Q    +            +C  G +CHNT  ++ C C +GF+  
Sbjct: 2    YRCNCSQGWTGALCDVQSVSCSVAASVRGVSEQDLCQNGGTCHNTGNTHMCTCASGFEGS 181

Query: 2643 QFSGGCQDINECGSSQAPCSYG--CSNTEGGYLCGCPPGY 2680
                   DINEC S  APC  G  C++  G Y C C PGY
Sbjct: 182  YCE---NDINECFS--APCQNGATCTDLIGRYTCTCEPGY 286

 Score = 40.8 bits (94), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 26/68 (38%), Positives = 36/68 (52%), Gaps = 1/68 (1%)
 Frame = +2

Query: 1618 LCQ-GGKCINTFGSFQCRCPTGYYLNEDTRVCDDVNECETPGICGPGTCYNTVGNYTCIC 1676
            LCQ GG C NT  +  C C +G+   E +   +D+NEC +       TC + +G YTC C
Sbjct: 104  LCQNGGTCHNTGNTHMCTCASGF---EGSYCENDINECFSAPCQNGATCTDLIGRYTCTC 274

Query: 1677 PPDYMQVN 1684
             P Y  +N
Sbjct: 275  EPGYQGLN 298

 Score = 40.0 bits (92), Expect = 0.014,   Method: Compositional matrix adjust.
 Identities = 43/139 (30%), Positives = 58/139 (41%), Gaps = 10/139 (7%)
 Frame = +2

Query: 1389 YRCLCKDGYTG-----DGFTCT---DLDECSEXXXXXXXXXXXXAPGGYRCECDMGFVPS 1440
            YRC C  G+TG        +C+    +   SE                + C C  GF   
Sbjct: 2    YRCNCSQGWTGALCDVQSVSCSVAASVRGVSEQDLCQNGGTCHNTGNTHMCTCASGF--- 172

Query: 1441 ADGKACE-DIDECSLPNICVFGTCHNLPGLFRCECEIGYELDRSGGNCT-DVNECLDPTT 1498
             +G  CE DI+EC         TC +L G + C CE GY+    G NC  D++EC +   
Sbjct: 173  -EGSYCENDINECFSAPCQNGATCTDLIGRYTCTCEPGYQ----GLNCEYDIDECHNQPC 337

Query: 1499 CISGNCVNTPGSYTCDCPP 1517
               G C +   +Y C CPP
Sbjct: 338  LNGGTCHDLVNTYKCSCPP 394

 Score = 39.7 bits (91), Expect = 0.020,   Method: Compositional matrix adjust.
 Identities = 34/91 (37%), Positives = 45/91 (49%), Gaps = 2/91 (2%)
 Frame = +2

Query: 709 YQALCSSGPGMTSAGTDINECALDPDICPNG-ICENLRGTYKCICNSGYEVDITGKNC-V 766
           +   C+SG   +    DINEC   P  C NG  C +L G Y C C  GY+    G NC  
Sbjct: 146 HMCTCASGFEGSYCENDINECFSAP--CQNGATCTDLIGRYTCTCEPGYQ----GLNCEY 307

Query: 767 DINECVLNSLLCDNGQCRNTPGSFVCTCPKG 797
           DI+EC     L + G C +   ++ C+CP G
Sbjct: 308 DIDECHNQPCL-NGGTCHDLVNTYKCSCPPG 397

 Score = 38.1 bits (87), Expect = 0.054,   Method: Compositional matrix adjust.
 Identities = 31/100 (31%), Positives = 40/100 (40%), Gaps = 8/100 (8%)
 Frame = +2

Query: 1429 YRCECDMGF------VPSADGKACEDIDECSLPNICVFG-TCHNLPGLFRCECEIGYELD 1481
            YRC C  G+      V S        +   S  ++C  G TCHN      C C  G+E  
Sbjct: 2    YRCNCSQGWTGALCDVQSVSCSVAASVRGVSEQDLCQNGGTCHNTGNTHMCTCASGFE-- 175

Query: 1482 RSGGNC-TDVNECLDPTTCISGNCVNTPGSYTCDCPPDFE 1520
              G  C  D+NEC          C +  G YTC C P ++
Sbjct: 176  --GSYCENDINECFSAPCQNGATCTDLIGRYTCTCEPGYQ 289

 Score = 37.7 bits (86), Expect = 0.065,   Method: Compositional matrix adjust.
 Identities = 28/73 (38%), Positives = 36/73 (49%), Gaps = 2/73 (2%)
 Frame = +2

Query: 1608 DIDECQELPGLCQ-GGKCINTFGSFQCRCPTGYY-LNEDTRVCDDVNECETPGICGPGTC 1665
            DI+EC   P  CQ G  C +  G + C C  GY  LN +     D++EC        GTC
Sbjct: 194  DINECFSAP--CQNGATCTDLIGRYTCTCEPGYQGLNCEY----DIDECHNQPCLNGGTC 355

Query: 1666 YNTVGNYTCICPP 1678
            ++ V  Y C CPP
Sbjct: 356  HDLVNTYKCSCPP 394

 Score = 37.4 bits (85), Expect = 0.098,   Method: Compositional matrix adjust.
 Identities = 34/93 (36%), Positives = 44/93 (47%), Gaps = 10/93 (10%)
 Frame = +2

Query: 98  NMCTCPSGQISPSCGSRSIQHCSIRCMNGGSCSD----DHCLCQKGYIGTHCGQPVCE-- 151
           +MCTC SG     C +   +  S  C NG +C+D      C C+ GY G +C   + E  
Sbjct: 146 HMCTCASGFEGSYCENDINECFSAPCQNGATCTDLIGRYTCTCEPGYQGLNCEYDIDECH 325

Query: 152 -SGCLNGGRC---VAPNRCACTYGFTGPQCERD 180
              CLNGG C   V   +C+C  G  G  CE D
Sbjct: 326 NQPCLNGGTCHDLVNTYKCSCPPGTQGLLCEMD 424

 Score = 36.2 bits (82), Expect = 0.22,   Method: Compositional matrix adjust.
 Identities = 36/108 (33%), Positives = 45/108 (41%), Gaps = 1/108 (0%)
 Frame = +2

Query: 2208 DINECAQNPLLCAFRCVNTYGSYECKCPVGYVLREDRRMCKDEDECAEGKHDCTEKQMEC 2267
            DINEC   P      C +  G Y C C  GY   +      D DEC      C      C
Sbjct: 194  DINECFSAPCQNGATCTDLIGRYTCTCEPGY---QGLNCEYDIDECH--NQPCLNGGT-C 355

Query: 2268 KNLIGTYMCICGPGYQRRPDGEGC-IDENECQTKPGICENGRCLNTLG 2314
             +L+ TY C C PG Q    G  C +DEN+C         G C++ +G
Sbjct: 356  HDLVNTYKCSCPPGTQ----GLLCEMDENDCLFDSTCHNGGTCVDKVG 487

 Score = 35.4 bits (80), Expect = 0.31,   Method: Compositional matrix adjust.
 Identities = 32/103 (31%), Positives = 50/103 (48%), Gaps = 1/103 (0%)
 Frame = +2

Query: 1214 CTNSDGSYECSCQPGFALMPDQRSCTDIDECEDNPNICDGGQCTNIPGEYRCLCYDGFMA 1273
            C N+  ++ C+C  GF     +    DI+EC   P   +G  CT++ G Y C C  G+  
Sbjct: 125  CHNTGNTHMCTCASGFEGSYCEN---DINECFSAPCQ-NGATCTDLIGRYTCTCEPGY-- 286

Query: 1274 SEDMKTCVDVNECDLNPNICLS-GTCENTKGSFICHCDMGYSG 1315
             + +    D++EC   P  CL+ GTC +   ++ C C  G  G
Sbjct: 287  -QGLNCEYDIDECHNQP--CLNGGTCHDLVNTYKCSCPPGTQG 406

 Score = 34.7 bits (78), Expect = 0.62,   Method: Compositional matrix adjust.
 Identities = 25/66 (37%), Positives = 35/66 (53%), Gaps = 2/66 (3%)
 Frame = +2

Query: 256 MCQ-GGNCINTVGSFECKCPAGHKFNEVSQKCE-DIDECSTIPGVCDGGECTNTVSSYFC 313
           +CQ GG C NT  +  C C +G +       CE DI+EC + P   +G  CT+ +  Y C
Sbjct: 104 LCQNGGTCHNTGNTHMCTCASGFE----GSYCENDINECFSAPCQ-NGATCTDLIGRYTC 268

Query: 314 KCPPGF 319
            C PG+
Sbjct: 269 TCEPGY 286

 Score = 33.1 bits (74), Expect = 1.7,   Method: Compositional matrix adjust.
 Identities = 44/163 (26%), Positives = 63/163 (38%), Gaps = 3/163 (1%)
 Frame = +2

Query: 2316 YTCECNDGFTASPTQDECLDNREGYCFSEVL-QNMCQIGSSNRNPVTKSECCCDGGRGWG 2374
            Y C C+ G+T +    + +          V  Q++CQ G +  N      C C  G    
Sbjct: 2    YRCNCSQGWTGALCDVQSVSCSVAASVRGVSEQDLCQNGGTCHNTGNTHMCTCASG---- 169

Query: 2375 PHCEICPFEGTVAYKKLCPHGRGFMTNGADIDECKVIHDVCRNGE-CVNDRGSYHCICKT 2433
                   FEG+                  DI+EC      C+NG  C +  G Y C C+ 
Sbjct: 170  -------FEGSYCEN--------------DINEC--FSAPCQNGATCTDLIGRYTCTCEP 280

Query: 2434 GYTPDITGTAC-VDLNECNQAPKPCNFICKNTEGSYQCSCPKG 2475
            GY     G  C  D++EC+  P      C +   +Y+CSCP G
Sbjct: 281  GY----QGLNCEYDIDECHNQPCLNGGTCHDLVNTYKCSCPPG 397
>11667
          Length = 1227

 Score = 60.1 bits (144), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 49/139 (35%), Positives = 65/139 (46%), Gaps = 22/139 (15%)
 Frame = +3

Query: 2408 CKVIHDVCRNGECVNDRGSYHCICKTGYTPDITGTACVDLNECNQAPKPCNFICKNTEGS 2467
            CKV H  C+N  C  D       CK G+T + T   C D+NEC+ +P      C NT+GS
Sbjct: 408  CKVCHISCKNS-CTGDGPKLCSECKDGWTHN-TDIGCQDINECDTSPCKDTEYCTNTQGS 581

Query: 2468 YQC-------------------SCPKGYILQEDGRSCKDLDECATKQHNCQ---FLCVNT 2505
            Y C                    C  GY LQ DG+ C D+DEC+     C     +C NT
Sbjct: 582  YMCMSCNVACDGCTGSGPDHCVKCSAGYYLQ-DGK-CLDMDECSEDGQLCSDEGQVCENT 755

Query: 2506 IGGFTCKCPPGFTQHHTAC 2524
            +G + C+C PG+ +   AC
Sbjct: 756  VGSYKCECQPGYNKIGDAC 812

 Score = 55.5 bits (132), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 36/104 (34%), Positives = 50/104 (48%), Gaps = 19/104 (18%)
 Frame = +3

Query: 2204 MTCEDINECAQNPLLCAFRCVNTYGSYEC-------------------KCPVGYVLREDR 2244
            + C+DINEC  +P      C NT GSY C                   KC  GY L++ +
Sbjct: 504  IGCQDINECDTSPCKDTEYCTNTQGSYMCMSCNVACDGCTGSGPDHCVKCSAGYYLQDGK 683

Query: 2245 RMCKDEDECAEGKHDCTEKQMECKNLIGTYMCICGPGYQRRPDG 2288
              C D DEC+E    C+++   C+N +G+Y C C PGY +  D 
Sbjct: 684  --CLDMDECSEDGQLCSDEGQVCENTVGSYKCECQPGYNKIGDA 809

 Score = 55.1 bits (131), Expect = 4e-07,   Method: Compositional matrix adjust.
 Identities = 39/104 (37%), Positives = 48/104 (46%), Gaps = 20/104 (19%)
 Frame = +3

Query: 1321 GCTDINECEIGAHNCGRHAVCTNTAGSFKC-------------------SCSPGWIGDGI 1361
            GC DINEC+     C     CTNT GS+ C                    CS G+     
Sbjct: 507  GCQDINECDTSP--CKDTEYCTNTQGSYMCMSCNVACDGCTGSGPDHCVKCSAGYYLQDG 680

Query: 1362 KCTDLDECSNGTHMCSQHAD-CKNTMGSYRCLCKDGYTGDGFTC 1404
            KC D+DECS    +CS     C+NT+GSY+C C+ GY   G  C
Sbjct: 681  KCLDMDECSEDGQLCSDEGQVCENTVGSYKCECQPGYNKIGDAC 812

 Score = 50.8 bits (120), Expect = 8e-06,   Method: Compositional matrix adjust.
 Identities = 38/115 (33%), Positives = 55/115 (47%), Gaps = 22/115 (19%)
 Frame = +3

Query: 477 ECNKGFQLDIRGECIDVDECEKNPCTGGE-CINNQGSYTC-------------------H 516
           EC  G+  +    C D++EC+ +PC   E C N QGSY C                    
Sbjct: 471 ECKDGWTHNTDIGCQDINECDTSPCKDTEYCTNTQGSYMCMSCNVACDGCTGSGPDHCVK 650

Query: 517 CRAGYQSTLTRTECRDIDECLQNGRICNN--GRCINTDGSFHCVCNAGFHVTRDG 569
           C AGY   L   +C D+DEC ++G++C++    C NT GS+ C C  G++   D 
Sbjct: 651 CSAGY--YLQDGKCLDMDECSEDGQLCSDEGQVCENTVGSYKCECQPGYNKIGDA 809

 Score = 49.7 bits (117), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 37/99 (37%), Positives = 47/99 (47%), Gaps = 22/99 (22%)
 Frame = +3

Query: 1070 CTDIDECRISPDLCGRGQ-CVNTPGDFEC-------------------KCDEGYESGFMM 1109
            C DI+EC  SP  C   + C NT G + C                   KC  GY   ++ 
Sbjct: 510  CQDINECDTSP--CKDTEYCTNTQGSYMCMSCNVACDGCTGSGPDHCVKCSAGY---YLQ 674

Query: 1110 MKNCMDIDECQRDPLLC--RGGICHNTEGSYRCECPPGH 1146
               C+D+DEC  D  LC   G +C NT GSY+CEC PG+
Sbjct: 675  DGKCLDMDECSEDGQLCSDEGQVCENTVGSYKCECQPGY 791

 Score = 49.7 bits (117), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 41/118 (34%), Positives = 56/118 (47%), Gaps = 22/118 (18%)
 Frame = +3

Query: 1267 CYDGFMASEDMKTCVDVNECDLNPNICLSGTCENTKGSFIC------------------- 1307
            C DG+  + D+  C D+NECD +P    +  C NT+GS++C                   
Sbjct: 474  CKDGWTHNTDI-GCQDINECDTSPCK-DTEYCTNTQGSYMCMSCNVACDGCTGSGPDHCV 647

Query: 1308 HCDMGYSGKKGKTGCTDINECEIGAHNCGRHA-VCTNTAGSFKCSCSPGW--IGDGIK 1362
             C  GY  + GK  C D++EC      C     VC NT GS+KC C PG+  IGD  +
Sbjct: 648  KCSAGYYLQDGK--CLDMDECSEDGQLCSDEGQVCENTVGSYKCECQPGYNKIGDACR 815

 Score = 49.3 bits (116), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 36/96 (37%), Positives = 46/96 (47%), Gaps = 21/96 (21%)
 Frame = +3

Query: 1973 CVDINECVLDPGKCAPGTCQNLDGSYRCI-------------------CPPGYSLQNDKC 2013
            C DINEC   P K     C N  GSY C+                   C  GY LQ+ KC
Sbjct: 510  CQDINECDTSPCK-DTEYCTNTQGSYMCMSCNVACDGCTGSGPDHCVKCSAGYYLQDGKC 686

Query: 2014 EDIDECVEEPEICAL--GTCSNTEGSFKCLCPEGFS 2047
             D+DEC E+ ++C+     C NT GS+KC C  G++
Sbjct: 687  LDMDECSEDGQLCSDEGQVCENTVGSYKCECQPGYN 794

 Score = 48.5 bits (114), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 57/196 (29%), Positives = 80/196 (40%), Gaps = 22/196 (11%)
 Frame = +3

Query: 154 CLNGGRCVAPNRCACTYGFTGPQCERDYRTGPCFTVVSNQMCQGQLSGIVCTKTLCCATV 213
           CL  G      +C CT G+ G  C+   + G   +  ++     ++  I C  +  C   
Sbjct: 282 CLGAGTREGSGKCKCTAGYEGKLCDS-CKAGYYQSEKNDTHTVCKVCHISCKNS--CTGD 452

Query: 214 GRAWGHPCEMCPAQPHPCRRGFIPNIRTGACQDVDECQAIPGMCQGGN-CINTVGSFEC- 271
           G          P     C+ G+  N   G CQD++EC   P  C+    C NT GS+ C 
Sbjct: 453 G----------PKLCSECKDGWTHNTDIG-CQDINECDTSP--CKDTEYCTNTQGSYMCM 593

Query: 272 ------------------KCPAGHKFNEVSQKCEDIDECSTIPGVC--DGGECTNTVSSY 311
                             KC AG+   +   KC D+DECS    +C  +G  C NTV SY
Sbjct: 594 SCNVACDGCTGSGPDHCVKCSAGYYLQD--GKCLDMDECSEDGQLCSDEGQVCENTVGSY 767

Query: 312 FCKCPPGFYTSPDGTR 327
            C+C PG+    D  R
Sbjct: 768 KCECQPGYNKIGDACR 815

 Score = 45.8 bits (107), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 62/210 (29%), Positives = 89/210 (42%), Gaps = 16/210 (7%)
 Frame = +3

Query: 1820 CQRNAECINTA---GSYRCDCKPGYRLTSTGQC------NDRNECQEIPNICS---HGQC 1867
            C+ N +C+      GS +C C  GY       C      +++N+   +  +C       C
Sbjct: 264  CKDNGKCLGAGTREGSGKCKCTAGYEGKLCDSCKAGYYQSEKNDTHTVCKVCHISCKNSC 443

Query: 1868 IDTVGSFYCLCHTGFKTNVDQTMCLDINECERDACGNGT-CRNTIGSFNC-RCNHGFILS 1925
                      C  G+  N D   C DINEC+   C +   C NT GS+ C  CN      
Sbjct: 444  TGDGPKLCSECKDGWTHNTD-IGCQDINECDTSPCKDTEYCTNTQGSYMCMSCN------ 602

Query: 1926 HNNDCIDVDECATGNGNLCRNGQCVNTVGSFQCRCNEGYEVAPDGRTCVDINECVLDPGK 1985
                 +  D C TG+G       CV        +C+ GY +  DG+ C+D++EC  D   
Sbjct: 603  -----VACDGC-TGSGP----DHCV--------KCSAGYYLQ-DGK-CLDMDECSEDGQL 722

Query: 1986 CAP--GTCQNLDGSYRCICPPGYSLQNDKC 2013
            C+     C+N  GSY+C C PGY+   D C
Sbjct: 723  CSDEGQVCENTVGSYKCECQPGYNKIGDAC 812

 Score = 41.2 bits (95), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 36/120 (30%), Positives = 54/120 (45%), Gaps = 21/120 (17%)
 Frame = +3

Query: 1743 TDEFATLCGSQRPGFVIDIYTGLPVDIDECREIPGVCENGVCINMVGSFRC--------- 1793
            T +   LC   + G+  +   G   DI+EC   P   +   C N  GS+ C         
Sbjct: 444  TGDGPKLCSECKDGWTHNTDIGCQ-DINECDTSPCK-DTEYCTNTQGSYMCMSCNVACDG 617

Query: 1794 ----------ECPVGFFYNDKLLVCEDIDEC-QNGPVCQRNAE-CINTAGSYRCDCKPGY 1841
                      +C  G++  D    C D+DEC ++G +C    + C NT GSY+C+C+PGY
Sbjct: 618  CTGSGPDHCVKCSAGYYLQDGK--CLDMDECSEDGQLCSDEGQVCENTVGSYKCECQPGY 791

 Score = 39.3 bits (90), Expect = 0.021,   Method: Compositional matrix adjust.
 Identities = 34/100 (34%), Positives = 41/100 (41%), Gaps = 22/100 (22%)
 Frame = +3

Query: 2607 CVDENECLSAHVCGGASCHNTLGSYKCM-------------------CPTGFQYEQFSGG 2647
            C D NEC ++       C NT GSY CM                   C  G+  +   G 
Sbjct: 510  CQDINECDTSPCKDTEYCTNTQGSYMCMSCNVACDGCTGSGPDHCVKCSAGYYLQ--DGK 683

Query: 2648 CQDINECGSSQAPCS---YGCSNTEGGYLCGCPPGYFRIG 2684
            C D++EC      CS     C NT G Y C C PGY +IG
Sbjct: 684  CLDMDECSEDGQLCSDEGQVCENTVGSYKCECQPGYNKIG 803

 Score = 38.1 bits (87), Expect = 0.048,   Method: Compositional matrix adjust.
 Identities = 32/109 (29%), Positives = 46/109 (42%), Gaps = 21/109 (19%)
 Frame = +3

Query: 1184 CNPGYHPTHDRLFCVDIDECSIMNGGCETFCTNSDGSYEC-------------------S 1224
            C  G+    D + C DI+EC         +CTN+ GSY C                    
Sbjct: 474  CKDGWTHNTD-IGCQDINECDTSPCKDTEYCTNTQGSYMCMSCNVACDGCTGSGPDHCVK 650

Query: 1225 CQPGFALMPDQRSCTDIDECEDNPNIC--DGGQCTNIPGEYRCLCYDGF 1271
            C  G+ L   +  C D+DEC ++  +C  +G  C N  G Y+C C  G+
Sbjct: 651  CSAGYYLQDGK--CLDMDECSEDGQLCSDEGQVCENTVGSYKCECQPGY 791

 Score = 36.2 bits (82), Expect = 0.19,   Method: Compositional matrix adjust.
 Identities = 33/100 (33%), Positives = 46/100 (46%), Gaps = 23/100 (23%)
 Frame = +3

Query: 1607 EDIDECQELPGLCQGGK-CINTFGSFQC-------------------RCPTGYYLNEDTR 1646
            +DI+EC   P  C+  + C NT GS+ C                   +C  GYYL +   
Sbjct: 513  QDINECDTSP--CKDTEYCTNTQGSYMCMSCNVACDGCTGSGPDHCVKCSAGYYLQDGK- 683

Query: 1647 VCDDVNECETPG-ICGP--GTCYNTVGNYTCICPPDYMQV 1683
             C D++EC   G +C      C NTVG+Y C C P Y ++
Sbjct: 684  -CLDMDECSEDGQLCSDEGQVCENTVGSYKCECQPGYNKI 800

 Score = 34.3 bits (77), Expect = 0.77,   Method: Compositional matrix adjust.
 Identities = 29/98 (29%), Positives = 47/98 (47%), Gaps = 10/98 (10%)
 Frame = +3

Query: 745 RGTYKCICNSGYEVDI-----TGKNCVDINE----CVLNSLLCDNGQCRNTPGSFVCTCP 795
            G+ KC C +GYE  +      G    + N+    C +  + C N  C          C 
Sbjct: 303 EGSGKCKCTAGYEGKLCDSCKAGYYQSEKNDTHTVCKVCHISCKN-SCTGDGPKLCSECK 479

Query: 796 KGFVYKPDLKTCEDIDECESSPCING-VCKNSPGSFIC 832
            G+ +  D+  C+DI+EC++SPC +   C N+ GS++C
Sbjct: 480 DGWTHNTDI-GCQDINECDTSPCKDTEYCTNTQGSYMC 590

 Score = 33.1 bits (74), Expect = 1.7,   Method: Compositional matrix adjust.
 Identities = 35/117 (29%), Positives = 53/117 (45%), Gaps = 3/117 (2%)
 Frame = +3

Query: 526 TRTECRDIDECLQNGRICNNGRCINT---DGSFHCVCNAGFHVTRDGKNCEDMDECSIRN 582
           T+  C+D  +CL  G    +G+C  T   +G     C AG++ +   KN +    C + +
Sbjct: 252 TQRPCKDNGKCLGAGTREGSGKCKCTAGYEGKLCDSCKAGYYQSE--KN-DTHTVCKVCH 422

Query: 583 MCLNGMCINEDGSFKCICKPGFQLASDGRYCKDINECETPGICMNGRCVNTDGSYRC 639
           +     C  +       CK G+   +D   C+DINEC+T        C NT GSY C
Sbjct: 423 ISCKNSCTGDGPKLCSECKDGWTHNTD-IGCQDINECDTSPCKDTEYCTNTQGSYMC 590

 Score = 32.3 bits (72), Expect = 3.0,   Method: Compositional matrix adjust.
 Identities = 32/110 (29%), Positives = 43/110 (39%), Gaps = 22/110 (20%)
 Frame = +3

Query: 1432 ECDMGFVPSADGKACEDIDECSLPNICVFGTCHNLPGLFRC------------------- 1472
            EC  G+  + D   C+DI+EC          C N  G + C                   
Sbjct: 471  ECKDGWTHNTD-IGCQDINECDTSPCKDTEYCTNTQGSYMCMSCNVACDGCTGSGPDHCV 647

Query: 1473 ECEIGYELDRSGGNCTDVNECLDPTTCISGN---CVNTPGSYTCDCPPDF 1519
            +C  GY L    G C D++EC +     S     C NT GSY C+C P +
Sbjct: 648  KCSAGYYL--QDGKCLDMDECSEDGQLCSDEGQVCENTVGSYKCECQPGY 791

 Score = 32.0 bits (71), Expect = 4.1,   Method: Compositional matrix adjust.
 Identities = 15/28 (53%), Positives = 20/28 (71%)
 Frame = +3

Query: 2647 GCQDINECGSSQAPCSYGCSNTEGGYLC 2674
            GCQDINEC +S    +  C+NT+G Y+C
Sbjct: 507  GCQDINECDTSPCKDTEYCTNTQGSYMC 590

 Score = 31.6 bits (70), Expect = 5.0,   Method: Compositional matrix adjust.
 Identities = 15/34 (44%), Positives = 22/34 (64%), Gaps = 2/34 (5%)
 Frame = +3

Query: 725 DINECALDPDICPN--GICENLRGTYKCICNSGY 756
           D++EC+ D  +C +   +CEN  G+YKC C  GY
Sbjct: 690 DMDECSEDGQLCSDEGQVCENTVGSYKCECQPGY 791

 Score = 31.2 bits (69), Expect = 6.7,   Method: Compositional matrix adjust.
 Identities = 23/46 (50%), Positives = 27/46 (58%), Gaps = 3/46 (6%)
 Frame = +3

Query: 2124 DDSAVDMDECKEP-DVCR-HGQ-CINTDGSYRCECPFGYILEGNEC 2166
            D   +DMDEC E   +C   GQ C NT GSY+CEC  GY   G+ C
Sbjct: 675  DGKCLDMDECSEDGQLCSDEGQVCENTVGSYKCECQPGYNKIGDAC 812
>13401
          Length = 497

 Score = 57.4 bits (137), Expect = 7e-08,   Method: Compositional matrix adjust.
 Identities = 63/169 (37%), Positives = 85/169 (50%), Gaps = 9/169 (5%)
 Frame = -3

Query: 2481 DGRSCK-DLDECATKQHNCQF--LCVNTIGGFTCKCPPGFTQHHTACIDN-NECTSDINL 2536
            DG+ C+ D++EC      C     C NT G FTC+CPP +T     C DN NEC  D   
Sbjct: 486  DGKRCQQDVNECNATTPVCYNGGTCTNTAGSFTCQCPPHWT--GPXCGDNINEC--DTKP 319

Query: 2537 CGSKGVCQNTPGSFTCECQ-RGFSLDQSGASCEDVDECEGNHRCQHG--CQNIIGGYRCS 2593
            C + G CQ+T   FTC C   GF   Q     E+VD+C  NHRC++G  C + I  Y C+
Sbjct: 318  CFNAGRCQDTVSGFTCHCSGTGF---QGNRCEENVDDCV-NHRCENGAPCVDGIRQYFCN 151

Query: 2594 CP-QGYLQHYQWNQCVDENECLSAHVCGGASCHNTLGSYKCMCP-TGFQ 2640
            C   GY   +      D +EC S+    G +C      ++C C  TG++
Sbjct: 150  CTGTGYEGEFCQ---TDTDECASSPCKNGGNCSQGNNKFQCTCTDTGYR 13

 Score = 52.4 bits (124), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 52/134 (38%), Positives = 67/134 (50%), Gaps = 4/134 (2%)
 Frame = -3

Query: 1282 DVNECDLNPNICLSG-TCENTKGSFICHCDMGYSGKKGKTGCTD-INECEIGAHNCGRHA 1339
            DVNEC+    +C +G TC NT GSF C C   ++G      C D INEC+     C    
Sbjct: 465  DVNECNATTPVCYNGGTCTNTAGSFTCQCPPHWTGPX----CGDNINECDTKP--CFNAG 304

Query: 1340 VCTNTAGSFKCSCSPGWIGDGIKCTD-LDECSNGTHMCSQHADCKNTMGSYRCLCK-DGY 1397
             C +T   F C CS G    G +C + +D+C N  H C   A C + +  Y C C   GY
Sbjct: 303  RCQDTVSGFTCHCS-GTGFQGNRCEENVDDCVN--HRCENGAPCVDGIRQYFCNCTGTGY 133

Query: 1398 TGDGFTCTDLDECS 1411
             G+ F  TD DEC+
Sbjct: 132  EGE-FCQTDTDECA 94

 Score = 51.2 bits (121), Expect = 6e-06,   Method: Compositional matrix adjust.
 Identities = 54/158 (34%), Positives = 75/158 (47%), Gaps = 4/158 (2%)
 Frame = -3

Query: 1809 EDIDECQ-NGPVCQRNAECINTAGSYRCDCKPGYRLTSTGQCNDRNECQEIPNICSHGQC 1867
            +D++EC    PVC     C NTAGS+ C C P +     G  ++ NEC   P   + G+C
Sbjct: 468  QDVNECNATTPVCYNGGTCTNTAGSFTCQCPPHWTGPXCG--DNINECDTKPCF-NAGRC 298

Query: 1868 IDTVGSFYCLCH-TGFKTNVDQTMCLDINECERDACGNGT-CRNTIGSFNCRCNHGFILS 1925
             DTV  F C C  TGF+ N  +    ++++C    C NG  C + I  + C C  G    
Sbjct: 297  QDTVSGFTCHCSGTGFQGNRCE---ENVDDCVNHRCENGAPCVDGIRQYFCNCT-GTGYE 130

Query: 1926 HNNDCIDVDECATGNGNLCRN-GQCVNTVGSFQCRCNE 1962
                  D DECA+   + C+N G C      FQC C +
Sbjct: 129  GEFCQTDTDECAS---SPCKNGGNCSQGNNKFQCTCTD 25

 Score = 48.1 bits (113), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 54/162 (33%), Positives = 79/162 (48%), Gaps = 5/162 (3%)
 Frame = -3

Query: 2526 DNNECTSDINLCGSKGVCQNTPGSFTCECQRGFSLDQSGASCEDVDECEGNHRCQHG-CQ 2584
            D NEC +   +C + G C NT GSFTC+C   ++    G   ++++EC+       G CQ
Sbjct: 465  DVNECNATTPVCYNGGTCTNTAGSFTCQCPPHWTGPXCG---DNINECDTKPCFNAGRCQ 295

Query: 2585 NIIGGYRCSCPQGYLQHYQWNQCVDENECLSAHVCGGASCHNTLGSYKCMCPTGFQYE-Q 2643
            + + G+ C C     Q  +  + VD  +C++     GA C + +  Y C C TG  YE +
Sbjct: 294  DTVSGFTCHCSGTGFQGNRCEENVD--DCVNHRCENGAPCVDGIRQYFCNC-TGTGYEGE 124

Query: 2644 FSGGCQ-DINECGSSQAPCSYG--CSNTEGGYLCGCPPGYFR 2682
            F   CQ D +EC SS  PC  G  CS     + C C    +R
Sbjct: 123  F---CQTDTDECASS--PCKNGGNCSQGNNKFQCTCTDTGYR 13

 Score = 47.4 bits (111), Expect = 9e-05,   Method: Compositional matrix adjust.
 Identities = 58/183 (31%), Positives = 80/183 (43%), Gaps = 5/183 (2%)
 Frame = -3

Query: 762 GKNCV-DINECVLNSLLCDNG-QCRNTPGSFVCTCPKGFVYKPDLKTCEDIDECESSPCI 819
           GK C  D+NEC   + +C NG  C NT GSF C CP  +   P     ++I+EC++ PC 
Sbjct: 483 GKRCQQDVNECNATTPVCYNGGTCTNTAGSFTCQCPPHWT-GPXCG--DNINECDTKPCF 313

Query: 820 N-GVCKNSPGSFICECSPESTLDPTKTICIETIKGTCWQTVIDGRCEININGATLKSECC 878
           N G C+++   F C CS                 GT +Q     RCE N++        C
Sbjct: 312 NAGRCQDTVSGFTCHCS-----------------GTGFQ---GNRCEENVDD-------C 214

Query: 879 SSLGAAWGSPCTICQLDPICGKGFSRIKGTQCE-DINECEVFPGVCKN-GLCVNSRGSFK 936
            +     G+PC        C    +  +G  C+ D +EC   P  CKN G C      F+
Sbjct: 213 VNHRCENGAPCVDGIRQYFCNCTGTGYEGEFCQTDTDECASSP--CKNGGNCSQGNNKFQ 40

Query: 937 CEC 939
           C C
Sbjct: 39  CTC 31

 Score = 46.6 bits (109), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 48/167 (28%), Positives = 75/167 (44%), Gaps = 2/167 (1%)
 Frame = -3

Query: 1105 SGFMMMKNCMDIDECQRDPLLC-RGGICHNTEGSYRCECPPGHQLSPNISACIDINECEL 1163
            +G+   +   D++EC     +C  GG C NT GS+ C+CPP H   P      +INEC+ 
Sbjct: 495  TGYDGKRCQQDVNECNATTPVCYNGGTCTNTAGSFTCQCPP-HWTGPXCGD--NINECDT 325

Query: 1164 SANLCPHGRCVNLIGKYQCACN-PGYHPTHDRLFCVDIDECSIMNGGCETFCTNSDGSYE 1222
                   GRC + +  + C C+  G+          ++D+C  +N  CE      DG  +
Sbjct: 324  KPCF-NAGRCQDTVSGFTCHCSGTGFQGNRCEE---NVDDC--VNHRCENGAPCVDGIRQ 163

Query: 1223 CSCQPGFALMPDQRSCTDIDECEDNPNICDGGQCTNIPGEYRCLCYD 1269
              C         +   TD DEC  +P   +GG C+    +++C C D
Sbjct: 162  YFCNCTGTGYEGEFCQTDTDECASSP-CKNGGNCSQGNNKFQCTCTD 25

 Score = 45.4 bits (106), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 33/92 (35%), Positives = 44/92 (47%)
 Frame = -3

Query: 1311 MGYSGKKGKTGCTDINECEIGAHNCGRHAVCTNTAGSFKCSCSPGWIGDGIKCTDLDECS 1370
             GY GK+ +    D+NEC      C     CTNTAGSF C C P W G      +++EC 
Sbjct: 495  TGYDGKRCQQ---DVNECNATTPVCYNGGTCTNTAGSFTCQCPPHWTGPXCG-DNINECD 328

Query: 1371 NGTHMCSQHADCKNTMGSYRCLCKDGYTGDGF 1402
              T  C     C++T+  + C C    +G GF
Sbjct: 327  --TKPCFNAGRCQDTVSGFTCHC----SGTGF 250

 Score = 45.4 bits (106), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 41/108 (37%), Positives = 50/108 (46%), Gaps = 2/108 (1%)
 Frame = -3

Query: 245 QDVDECQAIPGMC-QGGNCINTVGSFECKCPAGHKFNEVSQKCED-IDECSTIPGVCDGG 302
           QDV+EC A   +C  GG C NT GSF C+CP     +     C D I+EC T P   + G
Sbjct: 468 QDVNECNATTPVCYNGGTCTNTAGSFTCQCPP----HWTGPXCGDNINECDTKPCF-NAG 304

Query: 303 ECTNTVSSYFCKCPPGFYTSPDGTRCVDVRPGYCYTALANGRCSNQLP 350
            C +TVS + C C     T   G RC +           N RC N  P
Sbjct: 303 RCQDTVSGFTCHCSG---TGFQGNRCEEN-----VDDCVNHRCENGAP 184

 Score = 44.3 bits (103), Expect = 8e-04,   Method: Compositional matrix adjust.
 Identities = 48/160 (30%), Positives = 69/160 (43%), Gaps = 9/160 (5%)
 Frame = -3

Query: 1768 DIDECREIPGVCENG-VCINMVGSFRCECPVGFFYNDKLLVCEDIDECQNGPVCQRNAEC 1826
            D++EC     VC NG  C N  GSF C+CP  +         ++I+EC   P C     C
Sbjct: 465  DVNECNATTPVCYNGGTCTNTAGSFTCQCPPHW---TGPXCGDNINECDTKP-CFNAGRC 298

Query: 1827 INTAGSYRCDCKPGYRLTSTGQCNDRNECQE-----IPNICSHGQ-CIDTVGSFYCLCH- 1879
             +T   + C C        +G     N C+E     + + C +G  C+D +  ++C C  
Sbjct: 297  QDTVSGFTCHC--------SGTGFQGNRCEENVDDCVNHRCENGAPCVDGIRQYFCNCTG 142

Query: 1880 TGFKTNVDQTMCLDINECERDACGN-GTCRNTIGSFNCRC 1918
            TG++    QT   D +EC    C N G C      F C C
Sbjct: 141  TGYEGEFCQT---DTDECASSPCKNGGNCSQGNNKFQCTC 31

 Score = 43.9 bits (102), Expect = 9e-04,   Method: Compositional matrix adjust.
 Identities = 29/79 (36%), Positives = 40/79 (50%), Gaps = 1/79 (1%)
 Frame = -3

Query: 1607 EDIDECQELPGLC-QGGKCINTFGSFQCRCPTGYYLNEDTRVCDDVNECETPGICGPGTC 1665
            +D++EC     +C  GG C NT GSF C+CP  +         D++NEC+T      G C
Sbjct: 468  QDVNECNATTPVCYNGGTCTNTAGSFTCQCPPHW---TGPXCGDNINECDTKPCFNAGRC 298

Query: 1666 YNTVGNYTCICPPDYMQVN 1684
             +TV  +TC C     Q N
Sbjct: 297  QDTVSGFTCHCSGTGFQGN 241

 Score = 40.8 bits (94), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 42/150 (28%), Positives = 67/150 (44%), Gaps = 4/150 (2%)
 Frame = -3

Query: 455 CQLVRYLCQNG-RCIPTPGSYRCECNKGFQLDIRGECIDVDECEKNPC-TGGECINNQGS 512
           C     +C NG  C  T GS+ C+C   +     G+  +++EC+  PC   G C +    
Sbjct: 453 CNATTPVCYNGGTCTNTAGSFTCQCPPHWTGPXCGD--NINECDTKPCFNAGRCQDTVSG 280

Query: 513 YTCHCRA-GYQSTLTRTECRDIDECLQNGRICNNGRCINTDGSFHCVCNAGFHVTRDGKN 571
           +TCHC   G+Q         ++D+C+ N R  N   C++    + C C        +G+ 
Sbjct: 279 FTCHCSGTGFQGNRCE---ENVDDCV-NHRCENGAPCVDGIRQYFCNCTG---TGYEGEF 121

Query: 572 CE-DMDECSIRNMCLNGMCINEDGSFKCIC 600
           C+ D DEC+       G C   +  F+C C
Sbjct: 120 CQTDTDECASSPCKNGGNCSQGNNKFQCTC 31

 Score = 39.3 bits (90), Expect = 0.024,   Method: Compositional matrix adjust.
 Identities = 49/165 (29%), Positives = 73/165 (44%), Gaps = 11/165 (6%)
 Frame = -3

Query: 1072 DIDECRISPDLC-GRGQCVNTPGDFECKCDEGYESGFMMMKNCMD-IDECQRDPLLCRGG 1129
            D++EC  +  +C   G C NT G F C+C   +         C D I+EC   P     G
Sbjct: 465  DVNECNATTPVCYNGGTCTNTAGSFTCQCPPHW-----TGPXCGDNINECDTKPCF-NAG 304

Query: 1130 ICHNTEGSYRCECP----PGHQLSPNISACIDINECELSANLCPHGRCVNLIGKYQCACN 1185
             C +T   + C C      G++   N+  C++ + CE  A       CV+ I +Y C C 
Sbjct: 303  RCQDTVSGFTCHCSGTGFQGNRCEENVDDCVN-HRCENGA------PCVDGIRQYFCNCT 145

Query: 1186 -PGYHPTHDRLFC-VDIDECSI---MNGGCETFCTNSDGSYECSC 1225
              GY    +  FC  D DEC+     NGG    C+  +  ++C+C
Sbjct: 144  GTGY----EGEFCQTDTDECASSPCKNGG---NCSQGNNKFQCTC 31

 Score = 37.7 bits (86), Expect = 0.060,   Method: Compositional matrix adjust.
 Identities = 36/114 (31%), Positives = 56/114 (49%), Gaps = 3/114 (2%)
 Frame = -3

Query: 725 DINECALDPDICPNG-ICENLRGTYKCICNSGYEVDITGKNCVD-INECVLNSLLCDNGQ 782
           D+NEC     +C NG  C N  G++ C C   +    TG  C D INEC       + G+
Sbjct: 465 DVNECNATTPVCYNGGTCTNTAGSFTCQCPPHW----TGPXCGDNINECDTKPCF-NAGR 301

Query: 783 CRNTPGSFVCTCPKGFVYKPDLKTCEDIDECESSPCINGV-CKNSPGSFICECS 835
           C++T   F C C  G  ++ + +  E++D+C +  C NG  C +    + C C+
Sbjct: 300 CQDTVSGFTCHC-SGTGFQGN-RCEENVDDCVNHRCENGAPCVDGIRQYFCNCT 145

 Score = 36.6 bits (83), Expect = 0.16,   Method: Compositional matrix adjust.
 Identities = 31/98 (31%), Positives = 46/98 (46%), Gaps = 1/98 (1%)
 Frame = -3

Query: 1023 NGKPFFKDINECKMIPSLCTH-GKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPD 1081
            +GK   +D+NEC     +C + G C NT GSF C+C   +       N   I+EC   P 
Sbjct: 486  DGKRCQQDVNECNATTPVCYNGGTCTNTAGSFTCQCPPHWTGPXCGDN---INECDTKPC 316

Query: 1082 LCGRGQCVNTPGDFECKCDEGYESGFMMMKNCMDIDEC 1119
                G+C +T   F C C     +GF   +   ++D+C
Sbjct: 315  F-NAGRCQDTVSGFTCHCS---GTGFQGNRCEENVDDC 214

 Score = 35.8 bits (81), Expect = 0.26,   Method: Compositional matrix adjust.
 Identities = 48/158 (30%), Positives = 71/158 (44%), Gaps = 8/158 (5%)
 Frame = -3

Query: 492 DVDECEKNP---CTGGECINNQGSYTCHCRAGYQSTLTRTECRD-IDECLQNGRIC-NNG 546
           DV+EC         GG C N  GS+TC C   +    T   C D I+EC  + + C N G
Sbjct: 465 DVNECNATTPVCYNGGTCTNTAGSFTCQCPPHW----TGPXCGDNINEC--DTKPCFNAG 304

Query: 547 RCINTDGSFHCVCNA-GFHVTRDGKNCEDMDECSIRNMCLNGM-CINEDGSFKCICKPGF 604
           RC +T   F C C+  GF     G  CE+  +  + + C NG  C++    + C C    
Sbjct: 303 RCQDTVSGFTCHCSGTGFQ----GNRCEENVDDCVNHRCENGAPCVDGIRQYFCNCTG-- 142

Query: 605 QLASDGRYCK-DINECETPGICMNGRCVNTDGSYRCEC 641
               +G +C+ D +EC +      G C   +  ++C C
Sbjct: 141 -TGYEGEFCQTDTDECASSPCKNGGNCSQGNNKFQCTC 31

 Score = 35.8 bits (81), Expect = 0.27,   Method: Compositional matrix adjust.
 Identities = 53/163 (32%), Positives = 70/163 (42%), Gaps = 11/163 (6%)
 Frame = -3

Query: 1893 DINECERD--ACGNG-TCRNTIGSFNCRCNHGFILSHNNDCIDVDECATGNGNLCRN-GQ 1948
            D+NEC      C NG TC NT GSF C+C   +      D  +++EC T     C N G+
Sbjct: 465  DVNECNATTPVCYNGGTCTNTAGSFTCQCPPHWTGPXCGD--NINECDT---KPCFNAGR 301

Query: 1949 CVNTVGSFQCRCNEGYEVAPDGRTCVDINECVLDPGKCAPGTCQN----LDG--SYRCIC 2002
            C +TV  F C C+          T    N C  +   C    C+N    +DG   Y C C
Sbjct: 300  CQDTVSGFTCHCS---------GTGFQGNRCEENVDDCVNHRCENGAPCVDGIRQYFCNC 148

Query: 2003 PPGYSLQNDKCE-DIDECVEEPEICALGTCSNTEGSFKCLCPE 2044
              G   + + C+ D DEC   P     G CS     F+C C +
Sbjct: 147  T-GTGYEGEFCQTDTDECASSP-CKNGGNCSQGNNKFQCTCTD 25

 Score = 35.0 bits (79), Expect = 0.38,   Method: Compositional matrix adjust.
 Identities = 36/93 (38%), Positives = 46/93 (49%), Gaps = 4/93 (4%)
 Frame = -3

Query: 1969 DGRTCV-DINECVLDPGKCAPG-TCQNLDGSYRCICPPGYSLQNDKCED-IDECVEEPEI 2025
            DG+ C  D+NEC      C  G TC N  GS+ C CPP ++     C D I+EC  +P  
Sbjct: 486  DGKRCQQDVNECNATTPVCYNGGTCTNTAGSFTCQCPPHWT--GPXCGDNINECDTKPCF 313

Query: 2026 CALGTCSNTEGSFKCLCP-EGFSLSSTGRRCQD 2057
             A G C +T   F C C   GF     G RC++
Sbjct: 312  NA-GRCQDTVSGFTCHCSGTGFQ----GNRCEE 229

 Score = 35.0 bits (79), Expect = 0.48,   Method: Compositional matrix adjust.
 Identities = 40/123 (32%), Positives = 53/123 (43%), Gaps = 7/123 (5%)
 Frame = -3

Query: 2207 EDINECAQNPLLCAFRCVNTYGSYECKCPVGYVLREDRRMCKDEDECAEGKHDCTEKQME 2266
            ++INEC   P   A RC +T   + C C  G   + +R        C E   DC   + E
Sbjct: 348  DNINECDTKPCFNAGRCQDTVSGFTCHCS-GTGFQGNR--------CEENVDDCVNHRCE 196

Query: 2267 ----CKNLIGTYMCIC-GPGYQRRPDGEGC-IDENECQTKPGICEN-GRCLNTLGSYTCE 2319
                C + I  Y C C G GY+    GE C  D +EC + P  C+N G C      + C 
Sbjct: 195  NGAPCVDGIRQYFCNCTGTGYE----GEFCQTDTDECASSP--CKNGGNCSQGNNKFQCT 34

Query: 2320 CND 2322
            C D
Sbjct: 33   CTD 25

 Score = 34.3 bits (77), Expect = 0.81,   Method: Compositional matrix adjust.
 Identities = 25/64 (39%), Positives = 32/64 (50%), Gaps = 2/64 (3%)
 Frame = -3

Query: 1637 TGYYLNEDTRVCDDVNECE--TPGICGPGTCYNTVGNYTCICPPDYMQVNGGNNCMDMRR 1694
            TGY   +  R   DVNEC   TP     GTC NT G++TC CPP +     G+N  +   
Sbjct: 495  TGY---DGKRCQQDVNECNATTPVCYNGGTCTNTAGSFTCQCPPHWTGPXCGDNINECDT 325

Query: 1695 SLCY 1698
              C+
Sbjct: 324  KPCF 313

 Score = 33.9 bits (76), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 20/52 (38%), Positives = 26/52 (50%), Gaps = 1/52 (1%)
 Frame = -3

Query: 911 EDINECEVFPGVCKNG-LCVNSRGSFKCECPNGMTLDATGRICLDIRLETCF 961
           +D+NEC     VC NG  C N+ GSF C+CP   T    G    +   + CF
Sbjct: 468 QDVNECNATTPVCYNGGTCTNTAGSFTCQCPPHWTGPXCGDNINECDTKPCF 313

 Score = 33.1 bits (74), Expect = 1.8,   Method: Compositional matrix adjust.
 Identities = 53/190 (27%), Positives = 74/190 (38%), Gaps = 4/190 (2%)
 Frame = -3

Query: 2287 DGEGCI-DENECQTKPGICENG-RCLNTLGSYTCECNDGFTASPTQDECLDNREGYCFSE 2344
            DG+ C  D NEC     +C NG  C NT GS+TC+C   +T       C DN        
Sbjct: 486  DGKRCQQDVNECNATTPVCYNGGTCTNTAGSFTCQCPPHWTGP----XCGDN-------- 343

Query: 2345 VLQNMCQIGSSNRNPVTKSECCCDGGRGWGPHCEICPFEGTVAYKKLCPHGRGFMTNGAD 2404
                   I   +  P   +  C D   G+  HC    F+G    +              +
Sbjct: 342  -------INECDTKPCFNAGRCQDTVSGFTCHCSGTGFQGNRCEE--------------N 226

Query: 2405 IDECKVIHDVCRNGE-CVNDRGSYHCICK-TGYTPDITGTACVDLNECNQAPKPCNFICK 2462
            +D+C  ++  C NG  CV+    Y C C  TGY  +   T   D +EC  +P      C 
Sbjct: 225  VDDC--VNHRCENGAPCVDGIRQYFCNCTGTGYEGEFCQT---DTDECASSPCKNGGNCS 61

Query: 2463 NTEGSYQCSC 2472
                 +QC+C
Sbjct: 60   QGNNKFQCTC 31

 Score = 32.7 bits (73), Expect = 2.4,   Method: Compositional matrix adjust.
 Identities = 26/77 (33%), Positives = 37/77 (48%), Gaps = 3/77 (3%)
 Frame = -3

Query: 1442 DGKACE-DIDECSLPNICVF--GTCHNLPGLFRCECEIGYELDRSGGNCTDVNECLDPTT 1498
            DGK C+ D++EC+      +  GTC N  G F C+C   +     G N   +NEC     
Sbjct: 486  DGKRCQQDVNECNATTPVCYNGGTCTNTAGSFTCQCPPHWTGPXCGDN---INECDTKPC 316

Query: 1499 CISGNCVNTPGSYTCDC 1515
              +G C +T   +TC C
Sbjct: 315  FNAGRCQDTVSGFTCHC 265

 Score = 32.0 bits (71), Expect = 3.6,   Method: Compositional matrix adjust.
 Identities = 42/132 (31%), Positives = 54/132 (40%), Gaps = 8/132 (6%)
 Frame = -3

Query: 531 RDIDECLQNGRIC-NNGRCINTDGSFHCVCNAGFHVTRDGKNCEDMDECSIRNMCLNGMC 589
           +D++EC     +C N G C NT GSF C C   +     G N   ++EC  +     G C
Sbjct: 468 QDVNECNATTPVCYNGGTCTNTAGSFTCQCPPHWTGPXCGDN---INECDTKPCFNAGRC 298

Query: 590 INEDGSFKCICK-PGFQLASDGRYCKDINECETPGICMNGRCVN----TDG--SYRCECF 642
            +    F C C   GFQ    G  C+     E    C+N RC N     DG   Y C C 
Sbjct: 297 QDTVSGFTCHCSGTGFQ----GNRCE-----ENVDDCVNHRCENGAPCVDGIRQYFCNC- 148

Query: 643 PGLAVGLDGRVC 654
                G +G  C
Sbjct: 147 --TGTGYEGEFC 118

 Score = 32.0 bits (71), Expect = 3.9,   Method: Compositional matrix adjust.
 Identities = 21/65 (32%), Positives = 30/65 (46%), Gaps = 1/65 (1%)
 Frame = -3

Query: 2014 EDIDECVEEPEICALG-TCSNTEGSFKCLCPEGFSLSSTGRRCQDLRMSYCYAKFEGGKC 2072
            +D++EC     +C  G TC+NT GSF C CP  ++    G    +     C   F  G+C
Sbjct: 468  QDVNECNATTPVCYNGGTCTNTAGSFTCQCPPHWTGPXCGDNINECDTKPC---FNAGRC 298

Query: 2073 SSPKS 2077
                S
Sbjct: 297  QDTVS 283

 Score = 31.6 bits (70), Expect = 4.3,   Method: Compositional matrix adjust.
 Identities = 50/158 (31%), Positives = 56/158 (35%), Gaps = 23/158 (14%)
 Frame = -3

Query: 139 GYIGTHCGQPVCESG-----CLNGGRC---VAPNRCACTYGFTGPQCERDYR---TGPCF 187
           GY G  C Q V E       C NGG C        C C   +TGP C  +     T PCF
Sbjct: 492 GYDGKRCQQDVNECNATTPVCYNGGTCTNTAGSFTCQCPPHWTGPXCGDNINECDTKPCF 313

Query: 188 TVVSNQMCQGQLSGIVC-------TKTLCCATVGRAWGHPCEMCPAQPHPCRRGFIPNIR 240
                  CQ  +SG  C           C   V     H CE         R+ F     
Sbjct: 312 NA---GRCQDTVSGFTCHCSGTGFQGNRCEENVDDCVNHRCENGAPCVDGIRQYFCNCTG 142

Query: 241 TGA----CQ-DVDECQAIPGMCQGGNCINTVGSFECKC 273
           TG     CQ D DEC + P    GGNC      F+C C
Sbjct: 141 TGYEGEFCQTDTDECASSPCK-NGGNCSQGNNKFQCTC 31

 Score = 31.6 bits (70), Expect = 4.8,   Method: Compositional matrix adjust.
 Identities = 17/33 (51%), Positives = 19/33 (57%), Gaps = 2/33 (6%)
 Frame = -3

Query: 1489 DVNEC--LDPTTCISGNCVNTPGSYTCDCPPDF 1519
            DVNEC    P     G C NT GS+TC CPP +
Sbjct: 465  DVNECNATTPVCYNGGTCTNTAGSFTCQCPPHW 367

 Score = 30.8 bits (68), Expect = 8.5,   Method: Compositional matrix adjust.
 Identities = 15/34 (44%), Positives = 21/34 (61%), Gaps = 2/34 (5%)
 Frame = -3

Query: 2649 QDINECGSSQAPCSYG--CSNTEGGYLCGCPPGY 2680
            QD+NEC ++   C  G  C+NT G + C CPP +
Sbjct: 468  QDVNECNATTPVCYNGGTCTNTAGSFTCQCPPHW 367
>18708
          Length = 481

 Score = 57.0 bits (136), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 29/60 (48%), Positives = 39/60 (65%), Gaps = 6/60 (10%)
 Frame = -3

Query: 2466 GSYQCSCPKGYILQEDGRSCKDLDECATKQHNC---QFLCVNTIGGFTC---KCPPGFTQ 2519
            GSY+C CP+G+ L+ DGRSC+D+DEC  K   C     +CVNT G + C   +CP GF +
Sbjct: 449  GSYRCECPEGWRLKRDGRSCEDIDECQEKTAYCPQQDSICVNTRGHYKCPVVRCPQGFAK 270

 Score = 51.2 bits (121), Expect = 6e-06,   Method: Compositional matrix adjust.
 Identities = 34/75 (45%), Positives = 41/75 (54%), Gaps = 8/75 (10%)
 Frame = -3

Query: 1986 CAPGTCQNLDGSYRCICPPGYSLQND--KCEDIDECVEEPEICAL--GTCSNTEGSFKC- 2040
            CA        GSYRC CP G+ L+ D   CEDIDEC E+   C      C NT G +KC 
Sbjct: 479  CAEAGVSIRPGSYRCECPEGWRLKRDGRSCEDIDECQEKTAYCPQQDSICVNTRGHYKCP 300

Query: 2041 --LCPEGFS-LSSTG 2052
               CP+GF+  +STG
Sbjct: 299  VVRCPQGFAKTASTG 255

 Score = 47.0 bits (110), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 27/58 (46%), Positives = 34/58 (58%), Gaps = 2/58 (3%)
 Frame = -3

Query: 1780 ENGVCINMVGSFRCECPVGFFYNDKLLVCEDIDECQNGPVC--QRNAECINTAGSYRC 1835
            E GV I   GS+RCECP G+        CEDIDECQ       Q+++ C+NT G Y+C
Sbjct: 473  EAGVSIR-PGSYRCECPEGWRLKRDGRSCEDIDECQEKTAYCPQQDSICVNTRGHYKC 303

 Score = 46.6 bits (109), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 30/71 (42%), Positives = 37/71 (52%), Gaps = 7/71 (9%)
 Frame = -3

Query: 2537 CGSKGVCQNTPGSFTCECQRGFSLDQSGASCEDVDEC-EGNHRCQHG---CQNIIGGYRC 2592
            C   GV    PGS+ CEC  G+ L + G SCED+DEC E    C      C N  G Y+C
Sbjct: 479  CAEAGVSIR-PGSYRCECPEGWRLKRDGRSCEDIDECQEKTAYCPQQDSICVNTRGHYKC 303

Query: 2593 ---SCPQGYLQ 2600
                CPQG+ +
Sbjct: 302  PVVRCPQGFAK 270

 Score = 44.3 bits (103), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 22/49 (44%), Positives = 28/49 (57%)
 Frame = -3

Query: 2228 GSYECKCPVGYVLREDRRMCKDEDECAEGKHDCTEKQMECKNLIGTYMC 2276
            GSY C+CP G+ L+ D R C+D DEC E    C ++   C N  G Y C
Sbjct: 449  GSYRCECPEGWRLKRDGRSCEDIDECQEKTAYCPQQDSICVNTRGHYKC 303

 Score = 43.5 bits (101), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 21/50 (42%), Positives = 31/50 (62%), Gaps = 4/50 (8%)
 Frame = -3

Query: 787 PGSFVCTCPKGFVYKPDLKTCEDIDECESS----PCINGVCKNSPGSFIC 832
           PGS+ C CP+G+  K D ++CEDIDEC+      P  + +C N+ G + C
Sbjct: 452 PGSYRCECPEGWRLKRDGRSCEDIDECQEKTAYCPQQDSICVNTRGHYKC 303

 Score = 43.1 bits (100), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 23/49 (46%), Positives = 29/49 (59%), Gaps = 2/49 (4%)
 Frame = -3

Query: 1136 GSYRCECPPGHQLSPNISACIDINECELSANLCPH--GRCVNLIGKYQC 1182
            GSYRCECP G +L  +  +C DI+EC+     CP     CVN  G Y+C
Sbjct: 449  GSYRCECPEGWRLKRDGRSCEDIDECQEKTAYCPQQDSICVNTRGHYKC 303

 Score = 43.1 bits (100), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 19/49 (38%), Positives = 30/49 (61%), Gaps = 3/49 (6%)
 Frame = -3

Query: 553 GSFHCVCNAGFHVTRDGKNCEDMDECSIRNMC---LNGMCINEDGSFKC 598
           GS+ C C  G+ + RDG++CED+DEC  +       + +C+N  G +KC
Sbjct: 449 GSYRCECPEGWRLKRDGRSCEDIDECQEKTAYCPQQDSICVNTRGHYKC 303

 Score = 42.7 bits (99), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 25/64 (39%), Positives = 35/64 (54%), Gaps = 8/64 (12%)
 Frame = -3

Query: 471 PGSYRCECNKGFQLDIRGE-CIDVDECEKN----PCTGGECINNQGSYTC---HCRAGYQ 522
           PGSYRCEC +G++L   G  C D+DEC++     P     C+N +G Y C    C  G+ 
Sbjct: 452 PGSYRCECPEGWRLKRDGRSCEDIDECQEKTAYCPQQDSICVNTRGHYKCPVVRCPQGFA 273

Query: 523 STLT 526
            T +
Sbjct: 272 KTAS 261

 Score = 42.7 bits (99), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 23/49 (46%), Positives = 31/49 (63%), Gaps = 3/49 (6%)
 Frame = -3

Query: 594 GSFKCICKPGFQLASDGRYCKDINEC-ETPGIC--MNGRCVNTDGSYRC 639
           GS++C C  G++L  DGR C+DI+EC E    C   +  CVNT G Y+C
Sbjct: 449 GSYRCECPEGWRLKRDGRSCEDIDECQEKTAYCPQQDSICVNTRGHYKC 303

 Score = 42.0 bits (97), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 25/61 (40%), Positives = 30/61 (49%), Gaps = 5/61 (8%)
 Frame = -3

Query: 1219 GSYECSCQPGFALMPDQRSCTDIDECEDNPNIC--DGGQCTNIPGEYRC---LCYDGFMA 1273
            GSY C C  G+ L  D RSC DIDEC++    C      C N  G Y+C    C  GF  
Sbjct: 449  GSYRCECPEGWRLKRDGRSCEDIDECQEKTAYCPQQDSICVNTRGHYKCPVVRCPQGFAK 270

Query: 1274 S 1274
            +
Sbjct: 269  T 267

 Score = 41.6 bits (96), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 20/49 (40%), Positives = 28/49 (57%), Gaps = 3/49 (6%)
 Frame = -3

Query: 1629 GSFQCRCPTGYYLNEDTRVCDDVNECETPGICGP---GTCYNTVGNYTC 1674
            GS++C CP G+ L  D R C+D++EC+      P     C NT G+Y C
Sbjct: 449  GSYRCECPEGWRLKRDGRSCEDIDECQEKTAYCPQQDSICVNTRGHYKC 303

 Score = 41.6 bits (96), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 23/58 (39%), Positives = 29/58 (50%), Gaps = 5/58 (8%)
 Frame = -3

Query: 267 GSFECKCPAGHKFNEVSQKCEDIDECSTIPGVCDGGE--CTNTVSSYFC---KCPPGF 319
           GS+ C+CP G +     + CEDIDEC      C   +  C NT   Y C   +CP GF
Sbjct: 449 GSYRCECPEGWRLKRDGRSCEDIDECQEKTAYCPQQDSICVNTRGHYKCPVVRCPQGF 276

 Score = 41.2 bits (95), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 25/64 (39%), Positives = 31/64 (48%), Gaps = 6/64 (9%)
 Frame = -3

Query: 1346 GSFKCSCSPGW--IGDGIKCTDLDECSNGTHMCSQH-ADCKNTMGSYRC---LCKDGYTG 1399
            GS++C C  GW    DG  C D+DEC   T  C Q  + C NT G Y+C    C  G+  
Sbjct: 449  GSYRCECPEGWRLKRDGRSCEDIDECQEKTAYCPQQDSICVNTRGHYKCPVVRCPQGFAK 270

Query: 1400 DGFT 1403
               T
Sbjct: 269  TAST 258

 Score = 40.8 bits (94), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 23/59 (38%), Positives = 32/59 (54%), Gaps = 5/59 (8%)
 Frame = -3

Query: 1954 GSFQCRCNEGYEVAPDGRTCVDINECVLDPGKCAP--GTCQNLDGSYRC---ICPPGYS 2007
            GS++C C EG+ +  DGR+C DI+EC      C      C N  G Y+C    CP G++
Sbjct: 449  GSYRCECPEGWRLKRDGRSCEDIDECQEKTAYCPQQDSICVNTRGHYKCPVVRCPQGFA 273

 Score = 40.8 bits (94), Expect = 0.009,   Method: Compositional matrix adjust.
 Identities = 22/58 (37%), Positives = 34/58 (58%), Gaps = 5/58 (8%)
 Frame = -3

Query: 1051 GSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQ--CVNTPGDFEC---KCDEGY 1103
            GS++C C  G+ L  + R+C DIDEC+     C +    CVNT G ++C   +C +G+
Sbjct: 449  GSYRCECPEGWRLKRDGRSCEDIDECQEKTAYCPQQDSICVNTRGHYKCPVVRCPQGF 276

 Score = 40.4 bits (93), Expect = 0.010,   Method: Compositional matrix adjust.
 Identities = 25/72 (34%), Positives = 34/72 (47%), Gaps = 6/72 (8%)
 Frame = -3

Query: 2619 CGGASCHNTLGSYKCMCPTGFQYEQFSGGCQDINECGSSQAPCSYG---CSNTEGGYLC- 2674
            C  A      GSY+C CP G++ ++    C+DI+EC    A C      C NT G Y C 
Sbjct: 479  CAEAGVSIRPGSYRCECPEGWRLKRDGRSCEDIDECQEKTAYCPQQDSICVNTRGHYKCP 300

Query: 2675 --GCPPGYFRIG 2684
               CP G+ +  
Sbjct: 299  VVRCPQGFAKTA 264

 Score = 40.4 bits (93), Expect = 0.010,   Method: Compositional matrix adjust.
 Identities = 23/61 (37%), Positives = 32/61 (52%), Gaps = 5/61 (8%)
 Frame = -3

Query: 2272 GTYMCICGPGYQRRPDGEGCIDENECQTKPGIC--ENGRCLNTLGSYTC---ECNDGFTA 2326
            G+Y C C  G++ + DG  C D +ECQ K   C  ++  C+NT G Y C    C  GF  
Sbjct: 449  GSYRCECPEGWRLKRDGRSCEDIDECQEKTAYCPQQDSICVNTRGHYKCPVVRCPQGFAK 270

Query: 2327 S 2327
            +
Sbjct: 269  T 267

 Score = 40.4 bits (93), Expect = 0.011,   Method: Compositional matrix adjust.
 Identities = 17/27 (62%), Positives = 20/27 (74%)
 Frame = -3

Query: 1426 PGGYRCECDMGFVPSADGKACEDIDEC 1452
            PG YRCEC  G+    DG++CEDIDEC
Sbjct: 452  PGSYRCECPEGWRLKRDGRSCEDIDEC 372

 Score = 38.9 bits (89), Expect = 0.029,   Method: Compositional matrix adjust.
 Identities = 21/59 (35%), Positives = 32/59 (54%), Gaps = 5/59 (8%)
 Frame = -3

Query: 746 GTYKCICNSGYEVDITGKNCVDINECVLNSLLC--DNGQCRNTPGSF---VCTCPKGFV 799
           G+Y+C C  G+ +   G++C DI+EC   +  C   +  C NT G +   V  CP+GF 
Sbjct: 449 GSYRCECPEGWRLKRDGRSCEDIDECQEKTAYCPQQDSICVNTRGHYKCPVVRCPQGFA 273

 Score = 38.5 bits (88), Expect = 0.040,   Method: Compositional matrix adjust.
 Identities = 22/58 (37%), Positives = 31/58 (53%), Gaps = 6/58 (10%)
 Frame = -3

Query: 2425 GSYHCICKTGYTPDITGTACVDLNECNQAPKPC---NFICKNTEGSYQC---SCPKGY 2476
            GSY C C  G+     G +C D++EC +    C   + IC NT G Y+C    CP+G+
Sbjct: 449  GSYRCECPEGWRLKRDGRSCEDIDECQEKTAYCPQQDSICVNTRGHYKCPVVRCPQGF 276

 Score = 38.1 bits (87), Expect = 0.057,   Method: Compositional matrix adjust.
 Identities = 23/67 (34%), Positives = 33/67 (49%), Gaps = 5/67 (7%)
 Frame = -3

Query: 1260 PGEYRCLCYDGFMASEDMKTCVDVNECDLNPNIC--LSGTCENTKGSFIC---HCDMGYS 1314
            PG YRC C +G+    D ++C D++EC      C      C NT+G + C    C  G++
Sbjct: 452  PGSYRCECPEGWRLKRDGRSCEDIDECQEKTAYCPQQDSICVNTRGHYKCPVVRCPQGFA 273

Query: 1315 GKKGKTG 1321
             K   TG
Sbjct: 272  -KTASTG 255

 Score = 38.1 bits (87), Expect = 0.058,   Method: Compositional matrix adjust.
 Identities = 27/70 (38%), Positives = 34/70 (48%), Gaps = 5/70 (7%)
 Frame = -3

Query: 1581 SVNTSEYKILCPGGEGFRPNPITVILEDIDECQELPGLC--QGGKCINTFGSFQC---RC 1635
            S+    Y+  CP  EG+R        EDIDECQE    C  Q   C+NT G ++C   RC
Sbjct: 461  SIRPGSYRCECP--EGWRLKRDGRSCEDIDECQEKTAYCPQQDSICVNTRGHYKCPVVRC 288

Query: 1636 PTGYYLNEDT 1645
            P G+     T
Sbjct: 287  PQGFAKTAST 258

 Score = 38.1 bits (87), Expect = 0.059,   Method: Compositional matrix adjust.
 Identities = 24/59 (40%), Positives = 31/59 (52%), Gaps = 5/59 (8%)
 Frame = -3

Query: 1092 PGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLC--RGGICHNTEGSYRC---ECPPG 1145
            PG + C+C EG+       ++C DIDECQ     C  +  IC NT G Y+C    CP G
Sbjct: 452  PGSYRCECPEGWRLK-RDGRSCEDIDECQEKTAYCPQQDSICVNTRGHYKCPVVRCPQG 279

 Score = 37.0 bits (84), Expect = 0.11,   Method: Compositional matrix adjust.
 Identities = 18/49 (36%), Positives = 27/49 (55%), Gaps = 1/49 (2%)
 Frame = -3

Query: 1303 GSFICHCDMGYSGKKGKTGCTDINECEIGAHNCGRH-AVCTNTAGSFKC 1350
            GS+ C C  G+  K+    C DI+EC+     C +  ++C NT G +KC
Sbjct: 449  GSYRCECPEGWRLKRDGRSCEDIDECQEKTAYCPQQDSICVNTRGHYKC 303

 Score = 36.2 bits (82), Expect = 0.20,   Method: Compositional matrix adjust.
 Identities = 23/58 (39%), Positives = 34/58 (58%), Gaps = 7/58 (12%)
 Frame = -3

Query: 898 CGKGFSRIK--GTQCEDINECEVFPGVC--KNGLCVNSRGSFKC---ECPNGMTLDAT 948
           C +G+ R+K  G  CEDI+EC+     C  ++ +CVN+RG +KC    CP G    A+
Sbjct: 431 CPEGW-RLKRDGRSCEDIDECQEKTAYCPQQDSICVNTRGHYKCPVVRCPQGFAKTAS 261

 Score = 35.8 bits (81), Expect = 0.23,   Method: Compositional matrix adjust.
 Identities = 22/59 (37%), Positives = 28/59 (47%), Gaps = 6/59 (10%)
 Frame = -3

Query: 1178 GKYQCACNPGYHPTHDRLFCVDIDECSIMNGGC---ETFCTNSDGSYEC---SCQPGFA 1230
            G Y+C C  G+    D   C DIDEC      C   ++ C N+ G Y+C    C  GFA
Sbjct: 449  GSYRCECPEGWRLKRDGRSCEDIDECQEKTAYCPQQDSICVNTRGHYKCPVVRCPQGFA 273

 Score = 35.0 bits (79), Expect = 0.45,   Method: Compositional matrix adjust.
 Identities = 24/71 (33%), Positives = 29/71 (40%), Gaps = 6/71 (8%)
 Frame = -3

Query: 2588 GGYRCSCPQGYLQHYQWNQCVDENECLSAHVC---GGASCHNTLGSYKC---MCPTGFQY 2641
            G YRC CP+G+        C D +EC           + C NT G YKC    CP GF  
Sbjct: 449  GSYRCECPEGWRLKRDGRSCEDIDECQEKTAYCPQQDSICVNTRGHYKCPVVRCPQGFAK 270

Query: 2642 EQFSGGCQDIN 2652
               +G    I 
Sbjct: 269  TASTGPQHSIR 237

 Score = 35.0 bits (79), Expect = 0.49,   Method: Compositional matrix adjust.
 Identities = 25/76 (32%), Positives = 33/76 (43%), Gaps = 10/76 (13%)
 Frame = -3

Query: 511 GSYTCHCRAGYQSTLTRTECRDIDECLQNGRIC--NNGRCINTDGSFHC---VCNAGFHV 565
           GSY C C  G++       C DIDEC +    C   +  C+NT G + C    C  GF  
Sbjct: 449 GSYRCECPEGWRLKRDGRSCEDIDECQEKTAYCPQQDSICVNTRGHYKCPVVRCPQGFAK 270

Query: 566 T-----RDGKNCEDMD 576
           T     +    C+ MD
Sbjct: 269 TASTGPQHSIRCKRMD 222

 Score = 33.9 bits (76), Expect = 0.98,   Method: Compositional matrix adjust.
 Identities = 15/33 (45%), Positives = 20/33 (60%)
 Frame = -3

Query: 2026 CALGTCSNTEGSFKCLCPEGFSLSSTGRRCQDL 2058
            CA    S   GS++C CPEG+ L   GR C+D+
Sbjct: 479  CAEAGVSIRPGSYRCECPEGWRLKRDGRSCEDI 381

 Score = 32.7 bits (73), Expect = 2.0,   Method: Compositional matrix adjust.
 Identities = 20/58 (34%), Positives = 27/58 (46%), Gaps = 7/58 (12%)
 Frame = -3

Query: 1872 GSFYCLCHTGFKTNVDQTMCLDINECERDAC----GNGTCRNTIGSFNC---RCNHGF 1922
            GS+ C C  G++   D   C DI+EC+         +  C NT G + C   RC  GF
Sbjct: 449  GSYRCECPEGWRLKRDGRSCEDIDECQEKTAYCPQQDSICVNTRGHYKCPVVRCPQGF 276

 Score = 32.7 bits (73), Expect = 2.3,   Method: Compositional matrix adjust.
 Identities = 16/26 (61%), Positives = 18/26 (69%), Gaps = 2/26 (7%)
 Frame = -3

Query: 2149 GSYRCECPFGYIL--EGNECVDTDEC 2172
            GSYRCECP G+ L  +G  C D DEC
Sbjct: 449  GSYRCECPEGWRLKRDGRSCEDIDEC 372

 Score = 31.6 bits (70), Expect = 4.9,   Method: Compositional matrix adjust.
 Identities = 15/28 (53%), Positives = 19/28 (67%), Gaps = 2/28 (7%)
 Frame = -3

Query: 1387 GSYRCLCKDGY--TGDGFTCTDLDECSE 1412
            GSYRC C +G+    DG +C D+DEC E
Sbjct: 449  GSYRCECPEGWRLKRDGRSCEDIDECQE 366

 Score = 31.2 bits (69), Expect = 7.1,   Method: Compositional matrix adjust.
 Identities = 16/39 (41%), Positives = 23/39 (58%), Gaps = 5/39 (12%)
 Frame = -3

Query: 243 ACQDVDECQAIPGMC--QGGNCINTVGSFEC---KCPAG 276
           +C+D+DECQ     C  Q   C+NT G ++C   +CP G
Sbjct: 395 SCEDIDECQEKTAYCPQQDSICVNTRGHYKCPVVRCPQG 279

 Score = 30.8 bits (68), Expect = 8.2,   Method: Compositional matrix adjust.
 Identities = 13/23 (56%), Positives = 15/23 (65%)
 Frame = -3

Query: 933 GSFKCECPNGMTLDATGRICLDI 955
           GS++CECP G  L   GR C DI
Sbjct: 449 GSYRCECPEGWRLKRDGRSCEDI 381
>26257
          Length = 466

 Score = 54.3 bits (129), Expect = 8e-07,   Method: Compositional matrix adjust.
 Identities = 45/114 (39%), Positives = 57/114 (50%), Gaps = 7/114 (6%)
 Frame = -2

Query: 1896 ECERDACGNGTCRNTIGSFNCRCNHGFILSHNNDCIDVDECATGNGNLCRNGQCVNTVGS 1955
            EC  D    G C   IG   C+C HG+I    N  +D+DECA G      N  C+N  G 
Sbjct: 432  ECHGDCLNGGKC---IGPNTCQCRHGYIGP--NCELDIDECALGLSACRGNSVCINEPGW 268

Query: 1956 FQCRCNEGYEVA-PD---GRTCVDINECV--LDPGKCAPGT-CQNLDGSYRCIC 2002
            + C C +G+  A PD   G  C+D+NECV   +   C P T C N +G Y C C
Sbjct: 267  YHCDCLQGFHSAWPDNHFGSLCLDVNECVGEGEGHTCHPSTRCVNTEGGYSCQC 106

 Score = 49.7 bits (117), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 46/114 (40%), Positives = 59/114 (51%), Gaps = 11/114 (9%)
 Frame = -2

Query: 539 NGRICNNGRCINTDGSFHCVCNAGFHVTRDGKNCE-DMDECSI-RNMCL-NGMCINEDGS 595
           +G   N G+CI   G   C C  G+     G NCE D+DEC++  + C  N +CINE G 
Sbjct: 426 HGDCLNGGKCI---GPNTCQCRHGY----IGPNCELDIDECALGLSACRGNSVCINEPGW 268

Query: 596 FKCICKPGFQLA----SDGRYCKDINECETPG---ICM-NGRCVNTDGSYRCEC 641
           + C C  GF  A      G  C D+NEC   G    C  + RCVNT+G Y C+C
Sbjct: 267 YHCDCLQGFHSAWPDNHFGSLCLDVNECVGEGEGHTCHPSTRCVNTEGGYSCQC 106

 Score = 48.9 bits (115), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 39/113 (34%), Positives = 53/113 (46%), Gaps = 13/113 (11%)
 Frame = -2

Query: 1043 HGKCRNT---IGSFKCRCDSGFALDSEERNCTDIDECRISPDLC-GRGQCVNTPGDFECK 1098
            HG C N    IG   C+C  G+   + E    DIDEC +    C G   C+N PG + C 
Sbjct: 426  HGDCLNGGKCIGPNTCQCRHGYIGPNCE---LDIDECALGLSACRGNSVCINEPGWYHCD 256

Query: 1099 CDEGYESGF---MMMKNCMDIDECQRDPLLCRGGICH------NTEGSYRCEC 1142
            C +G+ S +        C+D++EC  +     G  CH      NTEG Y C+C
Sbjct: 255  CLQGFHSAWPDNHFGSLCLDVNECVGEG---EGHTCHPSTRCVNTEGGYSCQC 106

 Score = 47.8 bits (112), Expect = 6e-05,   Method: Compositional matrix adjust.
 Identities = 45/120 (37%), Positives = 58/120 (48%), Gaps = 9/120 (7%)
 Frame = -2

Query: 1086 GQCVNTPGDFECKCDEGYESGFMMMKNC-MDIDECQRDPLLCRG-GICHNTEGSYRCECP 1143
            G+C+   G   C+C  GY     +  NC +DIDEC      CRG  +C N  G Y C+C 
Sbjct: 405  GKCI---GPNTCQCRHGY-----IGPNCELDIDECALGLSACRGNSVCINEPGWYHCDCL 250

Query: 1144 PG-HQLSPNI---SACIDINEC--ELSANLC-PHGRCVNLIGKYQCACNPGYHPTHDRLF 1196
             G H   P+    S C+D+NEC  E   + C P  RCVN  G Y C C    +  H  +F
Sbjct: 249  QGFHSAWPDNHFGSLCLDVNECVGEGEGHTCHPSTRCVNTEGGYSCQCGARENCLHSCIF 70

 Score = 45.1 bits (105), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 35/98 (35%), Positives = 48/98 (48%), Gaps = 9/98 (9%)
 Frame = -2

Query: 2506 IGGFTCKCPPGFTQHHTACIDNNECTSDINLCGSKGVCQNTPGSFTCECQRGFSL----D 2561
            IG  TC+C  G+   +   +D +EC   ++ C    VC N PG + C+C +GF      +
Sbjct: 396  IGPNTCQCRHGYIGPNCE-LDIDECALGLSACRGNSVCINEPGWYHCDCLQGFHSAWPDN 220

Query: 2562 QSGASCEDVDECEGN---HRCQHG--CQNIIGGYRCSC 2594
              G+ C DV+EC G    H C     C N  GGY C C
Sbjct: 219  HFGSLCLDVNECVGEGEGHTCHPSTRCVNTEGGYSCQC 106

 Score = 44.7 bits (104), Expect = 6e-04,   Method: Compositional matrix adjust.
 Identities = 18/33 (54%), Positives = 22/33 (66%)
 Frame = -2

Query: 148 PVCESGCLNGGRCVAPNRCACTYGFTGPQCERD 180
           P C   CLNGG+C+ PN C C +G+ GP CE D
Sbjct: 435 PECHGDCLNGGKCIGPNTCQCRHGYIGPNCELD 337

 Score = 43.9 bits (102), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 33/79 (41%), Positives = 41/79 (51%), Gaps = 10/79 (12%)
 Frame = -2

Query: 2404 DIDECKVIHDVCR-NGECVNDRGSYHCICKTGY---TPD-ITGTACVDLNEC-----NQA 2453
            DIDEC +    CR N  C+N+ G YHC C  G+    PD   G+ C+D+NEC        
Sbjct: 339  DIDECALGLSACRGNSVCINEPGWYHCDCLQGFHSAWPDNHFGSLCLDVNECVGEGEGHT 160

Query: 2454 PKPCNFICKNTEGSYQCSC 2472
              P +  C NTEG Y C C
Sbjct: 159  CHP-STRCVNTEGGYSCQC 106

 Score = 43.9 bits (102), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 38/96 (39%), Positives = 49/96 (51%), Gaps = 11/96 (11%)
 Frame = -2

Query: 1431 CECDMGFVPSADGKACE-DIDECSLPNICVFG--TCHNLPGLFRCECEIGYEL----DRS 1483
            C+C  G++    G  CE DIDEC+L      G   C N PG + C+C  G+      +  
Sbjct: 381  CQCRHGYI----GPNCELDIDECALGLSACRGNSVCINEPGWYHCDCLQGFHSAWPDNHF 214

Query: 1484 GGNCTDVNECL---DPTTCI-SGNCVNTPGSYTCDC 1515
            G  C DVNEC+   +  TC  S  CVNT G Y+C C
Sbjct: 213  GSLCLDVNECVGEGEGHTCHPSTRCVNTEGGYSCQC 106

 Score = 43.5 bits (101), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 45/147 (30%), Positives = 61/147 (41%), Gaps = 20/147 (13%)
 Frame = -2

Query: 495 ECEKNPCTGGECINNQGSYTCHCRAGYQSTLTRTECRDIDECLQNGRICN-NGRCINTDG 553
           EC  +   GG+CI   G  TC CR GY          DIDEC      C  N  CIN  G
Sbjct: 432 ECHGDCLNGGKCI---GPNTCQCRHGYIGPNCEL---DIDECALGLSACRGNSVCINEPG 271

Query: 554 SFHCVCNAGFHVT----RDGKNCEDMDECSIR---NMCL-NGMCINEDGSFKCICKP--- 602
            +HC C  GFH        G  C D++EC      + C  +  C+N +G + C C     
Sbjct: 270 WYHCDCLQGFHSAWPDNHFGSLCLDVNECVGEGEGHTCHPSTRCVNTEGGYSCQCGAREN 91

Query: 603 --------GFQLASDGRYCKDINECET 621
                   G +  +D  +   +++C T
Sbjct: 90  CLHSCIFQGAEHKNDSHWVSAVDKCMT 10

 Score = 42.0 bits (97), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 38/108 (35%), Positives = 53/108 (49%), Gaps = 11/108 (10%)
 Frame = -2

Query: 465 GRCIPTPGSYRCECNKGFQLDIRGEC-IDVDECEK--NPCTGGE-CINNQGSYTCHCRAG 520
           G+CI   G   C+C  G+   I   C +D+DEC    + C G   CIN  G Y C C  G
Sbjct: 405 GKCI---GPNTCQCRHGY---IGPNCELDIDECALGLSACRGNSVCINEPGWYHCDCLQG 244

Query: 521 YQSTLTRTE----CRDIDECLQNG--RICN-NGRCINTDGSFHCVCNA 561
           + S          C D++EC+  G    C+ + RC+NT+G + C C A
Sbjct: 243 FHSAWPDNHFGSLCLDVNECVGEGEGHTCHPSTRCVNTEGGYSCQCGA 100

 Score = 40.4 bits (93), Expect = 0.011,   Method: Compositional matrix adjust.
 Identities = 33/99 (33%), Positives = 42/99 (42%), Gaps = 8/99 (8%)
 Frame = -2

Query: 1303 GSFICHCDMGYSGKKGKTGCTDINECEIGAHNCGRHAVCTNTAGSFKCSCSPGWIGD--- 1359
            G   C C  GY G   +    DI+EC +G   C  ++VC N  G + C C  G+      
Sbjct: 393  GPNTCQCRHGYIGPNCEL---DIDECALGLSACRGNSVCINEPGWYHCDCLQGFHSAWPD 223

Query: 1360 ---GIKCTDLDEC--SNGTHMCSQHADCKNTMGSYRCLC 1393
               G  C D++EC      H C     C NT G Y C C
Sbjct: 222  NHFGSLCLDVNECVGEGEGHTCHPSTRCVNTEGGYSCQC 106

 Score = 40.0 bits (92), Expect = 0.014,   Method: Compositional matrix adjust.
 Identities = 32/78 (41%), Positives = 38/78 (48%), Gaps = 9/78 (11%)
 Frame = -2

Query: 1608 DIDECQELPGLCQGGK-CINTFGSFQCRCPTGYYL----NEDTRVCDDVNECETPG---I 1659
            DIDEC      C+G   CIN  G + C C  G++     N    +C DVNEC   G    
Sbjct: 339  DIDECALGLSACRGNSVCINEPGWYHCDCLQGFHSAWPDNHFGSLCLDVNECVGEGEGHT 160

Query: 1660 CGPGT-CYNTVGNYTCIC 1676
            C P T C NT G Y+C C
Sbjct: 159  CHPSTRCVNTEGGYSCQC 106

 Score = 39.3 bits (90), Expect = 0.022,   Method: Compositional matrix adjust.
 Identities = 38/110 (34%), Positives = 50/110 (45%), Gaps = 13/110 (11%)
 Frame = -2

Query: 1946 NGQCVNT---VGSFQCRCNEGYEVAPDGRTCVDINECVLDPGKC-APGTCQNLDGSYRCI 2001
            +G C+N    +G   C+C  GY + P+    +DI+EC L    C     C N  G Y C 
Sbjct: 426  HGDCLNGGKCIGPNTCQCRHGY-IGPNCE--LDIDECALGLSACRGNSVCINEPGWYHCD 256

Query: 2002 CPPGYSLQ------NDKCEDIDECVEEPE--ICALGT-CSNTEGSFKCLC 2042
            C  G+            C D++ECV E E   C   T C NTEG + C C
Sbjct: 255  CLQGFHSAWPDNHFGSLCLDVNECVGEGEGHTCHPSTRCVNTEGGYSCQC 106

 Score = 39.3 bits (90), Expect = 0.025,   Method: Compositional matrix adjust.
 Identities = 37/111 (33%), Positives = 53/111 (47%), Gaps = 14/111 (12%)
 Frame = -2

Query: 2417 NGECVNDR---GSYHCICKTGYTPDITGTAC-VDLNECNQAPKPC--NFICKNTEGSYQC 2470
            +G+C+N     G   C C+ GY     G  C +D++EC      C  N +C N  G Y C
Sbjct: 426  HGDCLNGGKCIGPNTCQCRHGYI----GPNCELDIDECALGLSACRGNSVCINEPGWYHC 259

Query: 2471 SCPKGYIL----QEDGRSCKDLDECATKQ--HNCQ--FLCVNTIGGFTCKC 2513
             C +G+         G  C D++EC  +   H C     CVNT GG++C+C
Sbjct: 258  DCLQGFHSAWPDNHFGSLCLDVNECVGEGEGHTCHPSTRCVNTEGGYSCQC 106

 Score = 38.9 bits (89), Expect = 0.034,   Method: Compositional matrix adjust.
 Identities = 40/147 (27%), Positives = 59/147 (40%), Gaps = 9/147 (6%)
 Frame = -2

Query: 1781 NGVCINM---VGSFRCECPVGFFYNDKLLVCEDIDECQNG-PVCQRNAECINTAGSYRCD 1836
            +G C+N    +G   C+C  G+   +  L   DIDEC  G   C+ N+ CIN  G Y CD
Sbjct: 426  HGDCLNGGKCIGPNTCQCRHGYIGPNCEL---DIDECALGLSACRGNSVCINEPGWYHCD 256

Query: 1837 CKPGYRLTSTGQCNDRNECQEIPNICSHGQCIDTVGSFYCLCHTGFKTNVDQTMCLDINE 1896
            C  G+                                     H+ +  N   ++CLD+NE
Sbjct: 255  CLQGF-------------------------------------HSAWPDNHFGSLCLDVNE 187

Query: 1897 CERDACGN-----GTCRNTIGSFNCRC 1918
            C  +  G+       C NT G ++C+C
Sbjct: 186  CVGEGEGHTCHPSTRCVNTEGGYSCQC 106

 Score = 38.1 bits (87), Expect = 0.050,   Method: Compositional matrix adjust.
 Identities = 35/99 (35%), Positives = 47/99 (47%), Gaps = 8/99 (8%)
 Frame = -2

Query: 1219 GSYECSCQPGFALMPDQRSCTDIDECEDNPNICDGGQ-CTNIPGEYRCLCYDGFMAS--- 1274
            G   C C+ G+ + P+     DIDEC    + C G   C N PG Y C C  GF ++   
Sbjct: 393  GPNTCQCRHGY-IGPNCE--LDIDECALGLSACRGNSVCINEPGWYHCDCLQGFHSAWPD 223

Query: 1275 -EDMKTCVDVNEC--DLNPNICLSGT-CENTKGSFICHC 1309
                  C+DVNEC  +   + C   T C NT+G + C C
Sbjct: 222  NHFGSLCLDVNECVGEGEGHTCHPSTRCVNTEGGYSCQC 106

 Score = 37.0 bits (84), Expect = 0.11,   Method: Compositional matrix adjust.
 Identities = 28/79 (35%), Positives = 37/79 (46%), Gaps = 11/79 (13%)
 Frame = -2

Query: 452 TDYCQLVRYLCQ-NGRCIPTPGSYRCECNKGFQL-----DIRGECIDVDEC----EKNPC 501
            D C L    C+ N  CI  PG Y C+C +GF            C+DV+EC    E + C
Sbjct: 336 IDECALGLSACRGNSVCINEPGWYHCDCLQGFHSAWPDNHFGSLCLDVNECVGEGEGHTC 157

Query: 502 T-GGECINNQGSYTCHCRA 519
                C+N +G Y+C C A
Sbjct: 156 HPSTRCVNTEGGYSCQCGA 100

 Score = 37.0 bits (84), Expect = 0.12,   Method: Compositional matrix adjust.
 Identities = 41/128 (32%), Positives = 55/128 (42%), Gaps = 12/128 (9%)
 Frame = -2

Query: 746 GTYKCICNSGYEVDITGKNC-VDINECVLNSLLC-DNGQCRNTPGSFVCTCPKGF-VYKP 802
           G   C C  GY     G NC +DI+EC L    C  N  C N PG + C C +GF    P
Sbjct: 393 GPNTCQCRHGY----IGPNCELDIDECALGLSACRGNSVCINEPGWYHCDCLQGFHSAWP 226

Query: 803 DLK---TCEDIDEC----ESSPCINGV-CKNSPGSFICEC-SPESTLDPTKTICIETIKG 853
           D      C D++EC    E   C     C N+ G + C+C + E+ L        E    
Sbjct: 225 DNHFGSLCLDVNECVGEGEGHTCHPSTRCVNTEGGYSCQCGARENCLHSCIFQGAEHKND 46

Query: 854 TCWQTVID 861
           + W + +D
Sbjct: 45  SHWVSAVD 22

 Score = 35.8 bits (81), Expect = 0.29,   Method: Compositional matrix adjust.
 Identities = 36/100 (36%), Positives = 47/100 (47%), Gaps = 7/100 (7%)
 Frame = -2

Query: 2228 GSYECKCPVGYVLREDRRMCKDEDECAEGKHDCTEKQMECKNLIGTYMCICGPGYQRR-P 2286
            G   C+C  GY+         D DECA G   C    + C N  G Y C C  G+    P
Sbjct: 393  GPNTCQCRHGYIGPNCEL---DIDECALGLSACRGNSV-CINEPGWYHCDCLQGFHSAWP 226

Query: 2287 D---GEGCIDENEC--QTKPGICE-NGRCLNTLGSYTCEC 2320
            D   G  C+D NEC  + +   C  + RC+NT G Y+C+C
Sbjct: 225  DNHFGSLCLDVNECVGEGEGHTCHPSTRCVNTEGGYSCQC 106

 Score = 35.4 bits (80), Expect = 0.38,   Method: Compositional matrix adjust.
 Identities = 30/97 (30%), Positives = 40/97 (41%), Gaps = 9/97 (9%)
 Frame = -2

Query: 1346 GSFKCSCSPGWIGDGIKCTDLDECSNGTHMCSQHADCKNTMGSYRCLCKDGYTGD----- 1400
            G   C C  G+IG   +  D+DEC+ G   C  ++ C N  G Y C C  G+        
Sbjct: 393  GPNTCQCRHGYIGPNCE-LDIDECALGLSACRGNSVCINEPGWYHCDCLQGFHSAWPDNH 217

Query: 1401 -GFTCTDLDEC---SEXXXXXXXXXXXXAPGGYRCEC 1433
             G  C D++EC    E              GGY C+C
Sbjct: 216  FGSLCLDVNECVGEGEGHTCHPSTRCVNTEGGYSCQC 106

 Score = 35.0 bits (79), Expect = 0.40,   Method: Compositional matrix adjust.
 Identities = 40/101 (39%), Positives = 45/101 (44%), Gaps = 11/101 (10%)
 Frame = -2

Query: 2587 IGGYRCSCPQGYLQHYQWNQCVDENEC-LSAHVCGGAS-CHNTLGSYKCMCPTGFQY--- 2641
            IG   C C  GY+     N  +D +EC L    C G S C N  G Y C C  GF     
Sbjct: 396  IGPNTCQCRHGYIGP---NCELDIDECALGLSACRGNSVCINEPGWYHCDCLQGFHSAWP 226

Query: 2642 -EQFSGGCQDINEC-----GSSQAPCSYGCSNTEGGYLCGC 2676
               F   C D+NEC     G +  P S  C NTEGGY C C
Sbjct: 225  DNHFGSLCLDVNECVGEGEGHTCHP-STRCVNTEGGYSCQC 106

 Score = 33.1 bits (74), Expect = 1.8,   Method: Compositional matrix adjust.
 Identities = 29/81 (35%), Positives = 41/81 (50%), Gaps = 9/81 (11%)
 Frame = -2

Query: 260 GNCINT---VGSFECKCPAGHKFNEVSQKCE-DIDECSTIPGVCDGGE-CTNTVSSYFCK 314
           G+C+N    +G   C+C  G+    +   CE DIDEC+     C G   C N    Y C 
Sbjct: 423 GDCLNGGKCIGPNTCQCRHGY----IGPNCELDIDECALGLSACRGNSVCINEPGWYHCD 256

Query: 315 CPPGFYTS-PD---GTRCVDV 331
           C  GF+++ PD   G+ C+DV
Sbjct: 255 CLQGFHSAWPDNHFGSLCLDV 193

 Score = 32.0 bits (71), Expect = 3.3,   Method: Compositional matrix adjust.
 Identities = 32/97 (32%), Positives = 41/97 (42%), Gaps = 12/97 (12%)
 Frame = -2

Query: 231 CRRGFI-PNIRTGACQDVDECQAIPGMCQGGN-CINTVGSFECKCPAGHKF----NEVSQ 284
           CR G+I PN       D+DEC      C+G + CIN  G + C C  G       N    
Sbjct: 375 CRHGYIGPNCEL----DIDECALGLSACRGNSVCINEPGWYHCDCLQGFHSAWPDNHFGS 208

Query: 285 KCEDIDECSTIPGVCDGG------ECTNTVSSYFCKC 315
            C D++EC    G  +G        C NT   Y C+C
Sbjct: 207 LCLDVNECV---GEGEGHTCHPSTRCVNTEGGYSCQC 106
>09271
          Length = 1047

 Score = 53.9 bits (128), Expect = 8e-07,   Method: Compositional matrix adjust.
 Identities = 36/95 (37%), Positives = 46/95 (48%), Gaps = 9/95 (9%)
 Frame = -2

Query: 93   FCSRPNMCTCPSGQISPSCGSRSIQH-----CSIRCMNGGSC-SDDHCLCQKGYIGTHCG 146
             C RPN+C C +    P C  R   H     C   C+NGG C + + C C  GY G  C 
Sbjct: 1046 LCVRPNVCACRNHHTGPRCQRRLPSHPEYSQCQPACLNGGQCVAYNRCRCPPGYRGRRCQ 867

Query: 147  ---QPVCESGCLNGGRCVAPNRCACTYGFTGPQCE 178
               +P C   C NGG C+  NRC C  G +G +C+
Sbjct: 866  HAFRPDCRPPCSNGGTCLHGNRCQCPEGTSGHRCQ 762
>14158
          Length = 668

 Score = 50.4 bits (119), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 69/226 (30%), Positives = 101/226 (44%), Gaps = 13/226 (5%)
 Frame = +3

Query: 1782 GVCINMVGSFRCECPVGFFYNDKLLVCE------DIDECQNGPVCQRNAECINTAGSYRC 1835
             VC++ VGS+ C CP GF        CE      D + C N   C  N +    +  Y C
Sbjct: 3    AVCVDGVGSYTCVCPPGF----NGTRCETPYNACDNNSCANNSTCTVNPD---VSRGYVC 161

Query: 1836 DCKPGYRLTSTGQCNDRNECQEIPN-ICSH-GQCIDTV-GSFYCLCHTGFKTNVDQTMCL 1892
            DC       S   CN   E +   + +C + G C D V  SF C C  G+  ++ ++   
Sbjct: 162  DCADSNY--SGDLCNINIENKSCADGLCQNPGSCTDDVNASFTCACAPGYTGSLCES--- 326

Query: 1893 DINECERDACGNGTCRN--TIGSFNCRCNHGFILSHNNDCIDVDECATGNGNLC-RNGQC 1949
             IN C    C NGTC++  ++ +F C C  GF     +   ++D+C T   N C   G C
Sbjct: 327  PINYCVDLPCNNGTCQSNASLQNFTCECVEGFTGDVCD--ANIDDCQT---NTCFYGGTC 491

Query: 1950 VNTVGSFQCRCNEGYEVAPDGRTCVD-INECVLDPGKCAPGTCQNL 1994
            V+ +  + C C EGY     G+ C   +N+C  D   C  G C+ +
Sbjct: 492  VDGIDHWSCICAEGYS----GQWCQKMVNQC--DNNMCQSGVCREI 611

 Score = 43.9 bits (102), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 51/203 (25%), Positives = 76/203 (37%), Gaps = 15/203 (7%)
 Frame = +3

Query: 1212 TFCTNSDGSYECSCQPGFALMP--------DQRSCTDIDECEDNPNICDGGQCTNIPGEY 1263
              C +  GSY C C PGF            D  SC +   C  NP++  G         Y
Sbjct: 3    AVCVDGVGSYTCVCPPGFNGTRCETPYNACDNNSCANNSTCTVNPDVSRG---------Y 155

Query: 1264 RCLCYDGFMASEDMKTCVDVNECDLNPNICLSGTCEN-------TKGSFICHCDMGYSGK 1316
             C C D   +        D+   ++    C  G C+N          SF C C  GY+G 
Sbjct: 156  VCDCADSNYSG-------DLCNINIENKSCADGLCQNPGSCTDDVNASFTCACAPGYTGS 314

Query: 1317 KGKTGCTDINECEIGAHNCGRHAVCTNTAGSFKCSCSPGWIGDGIKCTDLDECSNGTHMC 1376
              ++      +       C  +A   N    F C C  G+ GD     ++D+C   T+ C
Sbjct: 315  LCESPINYCVDLPCNNGTCQSNASLQN----FTCECVEGFTGDVCD-ANIDDCQ--TNTC 473

Query: 1377 SQHADCKNTMGSYRCLCKDGYTG 1399
                 C + +  + C+C +GY+G
Sbjct: 474  FYGGTCVDGIDHWSCICAEGYSG 542

 Score = 43.1 bits (100), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 68/254 (26%), Positives = 105/254 (41%), Gaps = 8/254 (3%)
 Frame = +3

Query: 1663 GTCYNTVGNYTCICPPDYMQVNGGNNCMDMRRSLCYRNYYADNQTCDGELLFNMTKKMCC 1722
              C + VG+YTC+CPP +     G  C +   + C  N  A+N TC              
Sbjct: 3    AVCVDGVGSYTCVCPPGF----NGTRC-ETPYNACDNNSCANNSTCT------------- 128

Query: 1723 CSYNIGRAWNKPCEQCPIPSTDEFATLCGSQRPGFVIDIYTGLPVDIDECREIPGVCEN- 1781
             + ++ R +      C    ++    LC                ++I+      G+C+N 
Sbjct: 129  VNPDVSRGY-----VCDCADSNYSGDLCN---------------INIENKSCADGLCQNP 248

Query: 1782 GVCINMV-GSFRCECPVGF---FYNDKLLVCEDIDECQNGPVCQRNAECINTAGSYRCDC 1837
            G C + V  SF C C  G+        +  C D+  C NG  CQ NA   N    + C+C
Sbjct: 249  GSCTDDVNASFTCACAPGYTGSLCESPINYCVDL-PCNNG-TCQSNASLQN----FTCEC 410

Query: 1838 KPGYRLTSTGQCNDRN--ECQEIPNICSH-GQCIDTVGSFYCLCHTGFKTNVDQTMCLDI 1894
              G+    TG   D N  +CQ   N C + G C+D +  + C+C  G+     Q M   +
Sbjct: 411  VEGF----TGDVCDANIDDCQT--NTCFYGGTCVDGIDHWSCICAEGYSGQWCQKM---V 563

Query: 1895 NECERDACGNGTCR 1908
            N+C+ + C +G CR
Sbjct: 564  NQCDNNMCQSGVCR 605

 Score = 38.9 bits (89), Expect = 0.031,   Method: Compositional matrix adjust.
 Identities = 55/204 (26%), Positives = 78/204 (38%), Gaps = 16/204 (7%)
 Frame = +3

Query: 1129 GICHNTEGSYRCECPPGHQLSPNISACIDINECELSANLCPHGRCVNLIGKYQCACNPGY 1188
             +C +  GSY C CPPG   +           CE   N C +  C N      C  NP  
Sbjct: 3    AVCVDGVGSYTCVCPPGFNGT----------RCETPYNACDNNSCAN---NSTCTVNPDV 143

Query: 1189 HPTH-----DRLFCVDIDECSIMNGGC-ETFCTN-------SDGSYECSCQPGFALMPDQ 1235
               +     D  +  D+   +I N  C +  C N        + S+ C+C PG+     +
Sbjct: 144  SRGYVCDCADSNYSGDLCNINIENKSCADGLCQNPGSCTDDVNASFTCACAPGYTGSLCE 323

Query: 1236 RSCTDIDECEDNPNICDGGQCTNIPG--EYRCLCYDGFMASEDMKTCVDVNECDLNPNIC 1293
               + I+ C D P  C+ G C +      + C C +GF          D N  D   N C
Sbjct: 324  ---SPINYCVDLP--CNNGTCQSNASLQNFTCECVEGFTGDV-----CDANIDDCQTNTC 473

Query: 1294 L-SGTCENTKGSFICHCDMGYSGK 1316
               GTC +    + C C  GYSG+
Sbjct: 474  FYGGTCVDGIDHWSCICAEGYSGQ 545

 Score = 37.0 bits (84), Expect = 0.12,   Method: Compositional matrix adjust.
 Identities = 56/188 (29%), Positives = 76/188 (40%), Gaps = 17/188 (9%)
 Frame = +3

Query: 506 CINNQGSYTCHCRAGYQSTLTRTECRDIDECLQNGRICNNGRC-INTDGSFHCVCNAGFH 564
           C++  GSYTC C  G+  T   T     D    N    NN  C +N D S   VC+    
Sbjct: 9   CVDGVGSYTCVCPPGFNGTRCETPYNACD----NNSCANNSTCTVNPDVSRGYVCDCA-- 170

Query: 565 VTRDGKNCEDMDECSIRNM-CLNGMCINE-------DGSFKCICKPGFQLA---SDGRYC 613
              D     D+   +I N  C +G+C N        + SF C C PG+  +   S   YC
Sbjct: 171 ---DSNYSGDLCNINIENKSCADGLCQNPGSCTDDVNASFTCACAPGYTGSLCESPINYC 341

Query: 614 KDINECETPGICMNGRCVNTDG--SYRCECFPGLAVGLDGRVC---VDTHMRSTCYGGYR 668
            D+        C NG C +     ++ CEC  G      G VC   +D    +TC+ G  
Sbjct: 342 VDL-------PCNNGTCQSNASLQNFTCECVEGFT----GDVCDANIDDCQTNTCFYG-- 482

Query: 669 RGQCVKPL 676
            G CV  +
Sbjct: 483 -GTCVDGI 503

 Score = 37.0 bits (84), Expect = 0.13,   Method: Compositional matrix adjust.
 Identities = 58/224 (25%), Positives = 94/224 (41%), Gaps = 7/224 (3%)
 Frame = +3

Query: 1296 GTCENTKGSFICHCDMGYSGKKGKTGCTDINECEIGAHNCGRHAVCT---NTAGSFKCSC 1352
              C +  GS+ C C  G++G + +T     N C+   ++C  ++ CT   + +  + C C
Sbjct: 3    AVCVDGVGSYTCVCPPGFNGTRCET---PYNACD--NNSCANNSTCTVNPDVSRGYVCDC 167

Query: 1353 SPGWIGDGIKCTDLDECSNGTHMCSQHADCKNTM-GSYRCLCKDGYTGDGFTCTDLDECS 1411
            +       +   +++  S    +C     C + +  S+ C C  GYTG     + ++ C 
Sbjct: 168  ADSNYSGDLCNINIENKSCADGLCQNPGSCTDDVNASFTCACAPGYTG-SLCESPINYCV 344

Query: 1412 EXXXXXXXXXXXXAPGGYRCECDMGFVPSADGKACE-DIDECSLPNICVFG-TCHNLPGL 1469
            +            +   + CEC  GF     G  C+ +ID+C   N C +G TC +    
Sbjct: 345  DLPCNNGTCQSNASLQNFTCECVEGFT----GDVCDANIDDCQT-NTCFYGGTCVDGIDH 509

Query: 1470 FRCECEIGYELDRSGGNCTD-VNECLDPTTCISGNCVNTPGSYT 1512
            + C C  GY    SG  C   VN+C D   C SG C   P S  
Sbjct: 510  WSCICAEGY----SGQWCQKMVNQC-DNNMCQSGVCREIPESLV 626

 Score = 36.6 bits (83), Expect = 0.14,   Method: Compositional matrix adjust.
 Identities = 58/209 (27%), Positives = 80/209 (38%), Gaps = 53/209 (25%)
 Frame = +3

Query: 2460 ICKNTEGSYQCSCPKGYILQE--------DGRSCKD--------------LDECATKQHN 2497
            +C +  GSY C CP G+            D  SC +              + +CA   ++
Sbjct: 6    VCVDGVGSYTCVCPPGFNGTRCETPYNACDNNSCANNSTCTVNPDVSRGYVCDCADSNYS 185

Query: 2498 CQF-------------LCVN-------TIGGFTCKCPPGFTQHHTACIDNNECTSDINLC 2537
                            LC N           FTC C PG+T           C S IN C
Sbjct: 186  GDLCNINIENKSCADGLCQNPGSCTDDVNASFTCACAPGYTGSL--------CESPINYC 341

Query: 2538 G----SKGVCQNTPG--SFTCECQRGFSLDQSGASCEDVDECEGNHRCQHG--CQNIIGG 2589
                 + G CQ+     +FTCEC  GF+ D   A   ++D+C+ N  C +G  C + I  
Sbjct: 342  VDLPCNNGTCQSNASLQNFTCECVEGFTGDVCDA---NIDDCQTN-TCFYGGTCVDGIDH 509

Query: 2590 YRCSCPQGYLQHY---QWNQCVDENECLS 2615
            + C C +GY   +     NQC D N C S
Sbjct: 510  WSCICAEGYSGQWCQKMVNQC-DNNMCQS 593

 Score = 35.8 bits (81), Expect = 0.24,   Method: Compositional matrix adjust.
 Identities = 54/224 (24%), Positives = 88/224 (39%), Gaps = 17/224 (7%)
 Frame = +3

Query: 926  GLCVNSRGSFKCECPNGMTLDATGRICLDIRLETCFLKYDDEEC----TLPIAGRHRMDA 981
             +CV+  GS+ C CP G             R ET +   D+  C    T  +        
Sbjct: 3    AVCVDGVGSYTCVCPPGFN---------GTRCETPYNACDNNSCANNSTCTVNPDVSRGY 155

Query: 982  CCCSVGAAWGTEECEECPLRNSREYEELCPRGPGFATKDIT-----------NGKPFFKD 1030
             C    + +  + C    + N    + LC + PG  T D+             G      
Sbjct: 156  VCDCADSNYSGDLCNI-NIENKSCADGLC-QNPGSCTDDVNASFTCACAPGYTGSLCESP 329

Query: 1031 INECKMIPSLCTHGKCRN--TIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQC 1088
            IN C  +P  C +G C++  ++ +F C C  GF  D  + N   ID+C+ +    G G C
Sbjct: 330  INYCVDLP--CNNGTCQSNASLQNFTCECVEGFTGDVCDAN---IDDCQTNTCFYG-GTC 491

Query: 1089 VNTPGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRGGICH 1132
            V+    + C C EGY   +        +++C  +  +C+ G+C 
Sbjct: 492  VDGIDHWSCICAEGYSGQWCQKM----VNQCDNN--MCQSGVCR 605

 Score = 35.0 bits (79), Expect = 0.49,   Method: Compositional matrix adjust.
 Identities = 58/251 (23%), Positives = 92/251 (36%), Gaps = 6/251 (2%)
 Frame = +3

Query: 587 GMCINEDGSFKCICKPGFQLASDGRYCKDINECETP-GICMNGRCVNTDGSYRCECFPGL 645
            +C++  GS+ C+C PGF              CETP   C N  C N      C   P +
Sbjct: 3   AVCVDGVGSYTCVCPPGFNGT----------RCETPYNACDNNSCANNS---TCTVNPDV 143

Query: 646 AVGLDGRVCVDTHMRSTCYGGYRRGQCVKPLFGAVTKSECCCASTEYAFGEPCQ-PCPAQ 704
           + G         +    C        C   L                     CQ P    
Sbjct: 144 SRGYVCDCADSNYSGDLCNINIENKSCADGL---------------------CQNPGSCT 260

Query: 705 NSAEYQALCSSGPGMTSA--GTDINECALDPDICPNGICENLRG--TYKCICNSGYEVDI 760
           +       C+  PG T +   + IN C   P  C NG C++      + C C  G+  D+
Sbjct: 261 DDVNASFTCACAPGYTGSLCESPINYCVDLP--CNNGTCQSNASLQNFTCECVEGFTGDV 434

Query: 761 TGKNCVDINECVLNSLLCDNGQCRNTPGSFVCTCPKGFVYKPDLKTCEDIDECESSPCIN 820
              N   I++C  N+     G C +    + C C +G+  +   K    +++C+++ C +
Sbjct: 435 CDAN---IDDCQTNTCF-YGGTCVDGIDHWSCICAEGYSGQWCQKM---VNQCDNNMCQS 593

Query: 821 GVCKNSPGSFI 831
           GVC+  P S +
Sbjct: 594 GVCREIPESLV 626

 Score = 34.7 bits (78), Expect = 0.61,   Method: Compositional matrix adjust.
 Identities = 53/200 (26%), Positives = 81/200 (40%), Gaps = 20/200 (10%)
 Frame = +3

Query: 2501 LCVNTIGGFTCKCPPGFTQHHTACIDNNECTSDINLCGSKGVCQNTPGSFTCECQRGFSL 2560
            +CV+ +G +TC CPPGF        +   C +  N C +     N+  +   +  RG+  
Sbjct: 6    VCVDGVGSYTCVCPPGF--------NGTRCETPYNACDNNSCANNSTCTVNPDVSRGYVC 161

Query: 2561 D-----QSGASCEDVDECEGNHRCQHG-CQN-------IIGGYRCSCPQGY---LQHYQW 2604
            D      SG  C    E   N  C  G CQN       +   + C+C  GY   L     
Sbjct: 162  DCADSNYSGDLCNINIE---NKSCADGLCQNPGSCTDDVNASFTCACAPGYTGSLCESPI 332

Query: 2605 NQCVDENECLSAHVCGGASCHN--TLGSYKCMCPTGFQYEQFSGGCQDINECGSSQAPCS 2662
            N CVD         C   +C +  +L ++ C C  GF  +       +I++C ++   C 
Sbjct: 333  NYCVD-------LPCNNGTCQSNASLQNFTCECVEGFTGDVCDA---NIDDCQTNT--CF 476

Query: 2663 YGCSNTEG--GYLCGCPPGY 2680
            YG +  +G   + C C  GY
Sbjct: 477  YGGTCVDGIDHWSCICAEGY 536

 Score = 34.3 bits (77), Expect = 0.73,   Method: Compositional matrix adjust.
 Identities = 53/192 (27%), Positives = 80/192 (41%), Gaps = 10/192 (5%)
 Frame = +3

Query: 1339 AVCTNTAGSFKCSCSPGWIGDGIKC-TDLDECSNGTHMCSQHADCK---NTMGSYRCLCK 1394
            AVC +  GS+ C C PG+  +G +C T  + C N +  C+ ++ C    +    Y C C 
Sbjct: 3    AVCVDGVGSYTCVCPPGF--NGTRCETPYNACDNNS--CANNSTCTVNPDVSRGYVCDCA 170

Query: 1395 DG-YTGDGFTC-TDLDECSEXXXXXXXXXXXXAPGGYRCECDMGFVPSADGKACED-IDE 1451
            D  Y+GD      +   C++                + C C  G+     G  CE  I+ 
Sbjct: 171  DSNYSGDLCNINIENKSCADGLCQNPGSCTDDVNASFTCACAPGYT----GSLCESPINY 338

Query: 1452 C-SLPNICVFGTCHNLPGL--FRCECEIGYELDRSGGNCTDVNECLDPTTCISGNCVNTP 1508
            C  LP  C  GTC +   L  F CEC  G+  D    N   +++C   T    G CV+  
Sbjct: 339  CVDLP--CNNGTCQSNASLQNFTCECVEGFTGDVCDAN---IDDCQTNTCFYGGTCVDGI 503

Query: 1509 GSYTCDCPPDFE 1520
              ++C C   + 
Sbjct: 504  DHWSCICAEGYS 539

 Score = 34.3 bits (77), Expect = 0.83,   Method: Compositional matrix adjust.
 Identities = 29/99 (29%), Positives = 49/99 (49%), Gaps = 3/99 (3%)
 Frame = +3

Query: 453 DYCQLVRYLCQNGRCIPTPG--SYRCECNKGFQLDIRGECIDVDECEKNPC-TGGECINN 509
           +YC  V   C NG C       ++ CEC +GF  D+     ++D+C+ N C  GG C++ 
Sbjct: 333 NYC--VDLPCNNGTCQSNASLQNFTCECVEGFTGDVCDA--NIDDCQTNTCFYGGTCVDG 500

Query: 510 QGSYTCHCRAGYQSTLTRTECRDIDECLQNGRICNNGRC 548
              ++C C  GY     +   + +++C  N  +C +G C
Sbjct: 501 IDHWSCICAEGYSGQWCQ---KMVNQCDNN--MCQSGVC 602

 Score = 33.1 bits (74), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 56/194 (28%), Positives = 82/194 (42%), Gaps = 17/194 (8%)
 Frame = +3

Query: 1504 CVNTPGSYTCDCPPDFELNPTRV----------GCVDTRSGNCYLDIRPRGDNGDTACSN 1553
            CV+  GSYTC CPP F  N TR            C +  +     D+  RG   D A SN
Sbjct: 9    CVDGVGSYTCVCPPGF--NGTRCETPYNACDNNSCANNSTCTVNPDVS-RGYVCDCADSN 179

Query: 1554 EIG----VGVSKASCCCSLGKAWGTPCELCPSVNTSEYKILCPGGEGFRPNPITVILEDI 1609
              G    + +   SC   L +    P      VN S      PG  G      ++    I
Sbjct: 180  YSGDLCNINIENKSCADGLCQ---NPGSCTDDVNASFTCACAPGYTG------SLCESPI 332

Query: 1610 DECQELPGLCQGGKCIN--TFGSFQCRCPTGYYLNEDTRVCD-DVNECETPGICGPGTCY 1666
            + C +LP  C  G C +  +  +F C C  G+  +    VCD ++++C+T      GTC 
Sbjct: 333  NYCVDLP--CNNGTCQSNASLQNFTCECVEGFTGD----VCDANIDDCQTNTCFYGGTCV 494

Query: 1667 NTVGNYTCICPPDY 1680
            + + +++CIC   Y
Sbjct: 495  DGIDHWSCICAEGY 536

 Score = 32.0 bits (71), Expect = 3.3,   Method: Compositional matrix adjust.
 Identities = 36/125 (28%), Positives = 50/125 (40%), Gaps = 22/125 (17%)
 Frame = +3

Query: 77  GNQCIVPICRHSCGDGFCSRPNMCT----------CPSGQISPSCGSRSIQHCSIRCMNG 126
           G+ C + I   SC DG C  P  CT          C  G     C S  I +C     N 
Sbjct: 186 GDLCNINIENKSCADGLCQNPGSCTDDVNASFTCACAPGYTGSLCES-PINYCVDLPCNN 362

Query: 127 GSCSDDH------CLCQKGYIGTHCGQPV--CESG-CLNGGRCV---APNRCACTYGFTG 174
           G+C  +       C C +G+ G  C   +  C++  C  GG CV       C C  G++G
Sbjct: 363 GTCQSNASLQNFTCECVEGFTGDVCDANIDDCQTNTCFYGGTCVDGIDHWSCICAEGYSG 542

Query: 175 PQCER 179
             C++
Sbjct: 543 QWCQK 557

 Score = 31.6 bits (70), Expect = 5.0,   Method: Compositional matrix adjust.
 Identities = 53/212 (25%), Positives = 77/212 (36%), Gaps = 48/212 (22%)
 Frame = +3

Query: 467 CIPTPGSYRCECNKGFQLDI---------RGECIDVDECEKNP----------------- 500
           C+   GSY C C  GF                C +   C  NP                 
Sbjct: 9   CVDGVGSYTCVCPPGFNGTRCETPYNACDNNSCANNSTCTVNPDVSRGYVCDCADSNYSG 188

Query: 501 -----------CTGGECIN-------NQGSYTCHCRAGYQSTLTRTECRDIDECLQNGRI 542
                      C  G C N          S+TC C  GY  +L  +    I+ C+     
Sbjct: 189 DLCNINIENKSCADGLCQNPGSCTDDVNASFTCACAPGYTGSLCESP---INYCVD--LP 353

Query: 543 CNNGRCINTDG--SFHCVCNAGFHVTRDGKNCE-DMDECSIRNMCLNGMCINEDGSFKCI 599
           CNNG C +     +F C C  GF     G  C+ ++D+C        G C++    + CI
Sbjct: 354 CNNGTCQSNASLQNFTCECVEGFT----GDVCDANIDDCQTNTCFYGGTCVDGIDHWSCI 521

Query: 600 CKPGFQLASDGRYC-KDINECETPGICMNGRC 630
           C  G+     G++C K +N+C+   +C +G C
Sbjct: 522 CAEGYS----GQWCQKMVNQCDN-NMCQSGVC 602

 Score = 31.2 bits (69), Expect = 5.6,   Method: Compositional matrix adjust.
 Identities = 66/254 (25%), Positives = 97/254 (38%), Gaps = 11/254 (4%)
 Frame = +3

Query: 2309 CLNTLGSYTCECNDGFTASPTQDECLDNREGYCFSEVLQNMCQIGSS-NRNPVTKSECCC 2367
            C++ +GSYTC C  GF  +  +           ++    N C   S+   NP        
Sbjct: 9    CVDGVGSYTCVCPPGFNGTRCETP---------YNACDNNSCANNSTCTVNP-------- 137

Query: 2368 DGGRGWGPHCEICPFEGTVAYKKLCPHGRGFMTNGADIDECKVIHDVCRN-GECVND-RG 2425
            D  RG+   C    + G      LC           +I+       +C+N G C +D   
Sbjct: 138  DVSRGYVCDCADSNYSG-----DLC---------NINIENKSCADGLCQNPGSCTDDVNA 275

Query: 2426 SYHCICKTGYTPDITGTA---CVDLNECNQAPKPCNFICKNTEGSYQCSCPKGYILQEDG 2482
            S+ C C  GYT  +  +    CVDL  CN      N   +N    + C C +G+     G
Sbjct: 276  SFTCACAPGYTGSLCESPINYCVDL-PCNNGTCQSNASLQN----FTCECVEGFT----G 428

Query: 2483 RSC-KDLDECATKQHNCQFLCVNTIGGFTCKCPPGFT----QHHTACIDNNECTSDINLC 2537
              C  ++D+C T        CV+ I  ++C C  G++    Q      DNN C S     
Sbjct: 429  DVCDANIDDCQTNTCFYGGTCVDGIDHWSCICAEGYSGQWCQKMVNQCDNNMCQS----- 593

Query: 2538 GSKGVCQNTPGSFT 2551
               GVC+  P S  
Sbjct: 594  ---GVCREIPESLV 626
>25877
          Length = 434

 Score = 48.5 bits (114), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 27/72 (37%), Positives = 37/72 (51%), Gaps = 2/72 (2%)
 Frame = -1

Query: 2417 NGECVNDRGSYHCICKTGYTPDITGTACV--DLNECNQAPKPCNFICKNTEGSYQCSCPK 2474
            NG C     S  C C TGY  D     C+  D++ C Q P PC+  C +T+G + C C K
Sbjct: 368  NGGCKIVGDSQECFCNTGYQLDGDNKTCIFIDVDWCLQDPSPCDQTCNSTDGKFTCGCFK 189

Query: 2475 GYILQEDGRSCK 2486
            G+ L    R+C+
Sbjct: 188  GFQLNPGNRTCR 153

 Score = 48.5 bits (114), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 30/79 (37%), Positives = 45/79 (56%), Gaps = 2/79 (2%)
 Frame = -1

Query: 731 LDPDICPNGICENLRGTYKCICNSGYEVDITGKNC--VDINECVLNSLLCDNGQCRNTPG 788
           LD D+  NG C+ +  + +C CN+GY++D   K C  +D++ C+ +   CD   C +T G
Sbjct: 386 LDCDL-DNGGCKIVGDSQECFCNTGYQLDGDNKTCIFIDVDWCLQDPSPCDQ-TCNSTDG 213

Query: 789 SFVCTCPKGFVYKPDLKTC 807
            F C C KGF   P  +TC
Sbjct: 212 KFTCGCFKGFQLNPGNRTC 156

 Score = 45.1 bits (105), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 41/130 (31%), Positives = 55/130 (42%), Gaps = 12/130 (9%)
 Frame = -1

Query: 1252 DGGQCTNIPGEYRCLCYDGFMASEDMKTC--VDVNECDLNPNICLSGTCENTKGSFICHC 1309
            D G C  +     C C  G+    D KTC  +DV+ C  +P+ C   TC +T G F C C
Sbjct: 371  DNGGCKIVGDSQECFCNTGYQLDGDNKTCIFIDVDWCLQDPSPC-DQTCNSTDGKFTCGC 195

Query: 1310 DMGYSGKKGKTGCTDINECEIGAHNCG----------RHAVCTNTAGSFKCSCSPGWIGD 1359
              G+    G   C     C  G++  G           H  C +T G  +C C  GW G+
Sbjct: 194  FKGFQLNPGNRTC---RACSPGSYGXGCEEKCXCTAVNHVGCNSTTG--ECECRSGWTGE 30

Query: 1360 GIKCTDLDEC 1369
                 D+DEC
Sbjct: 29   ECD-EDIDEC 3

 Score = 43.9 bits (102), Expect = 9e-04,   Method: Compositional matrix adjust.
 Identities = 32/95 (33%), Positives = 45/95 (47%), Gaps = 4/95 (4%)
 Frame = -1

Query: 1966 VAPDGRTCVDINECVLDPGKCAPGTCQNLDGSYRCICPPGYSLQNDKCE----DIDECVE 2021
            VA DG +C     C         G C+ +  S  C C  GY L  D       D+D C++
Sbjct: 434  VAMDGFSCETSTTCSELDCDLDNGGCKIVGDSQECFCNTGYQLDGDNKTCIFIDVDWCLQ 255

Query: 2022 EPEICALGTCSNTEGSFKCLCPEGFSLSSTGRRCQ 2056
            +P  C   TC++T+G F C C +GF L+   R C+
Sbjct: 254  DPSPCDQ-TCNSTDGKFTCGCFKGFQLNPGNRTCR 153

 Score = 43.5 bits (101), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 25/65 (38%), Positives = 36/65 (55%), Gaps = 2/65 (3%)
 Frame = -1

Query: 1946 NGQCVNTVGSFQCRCNEGYEVAPDGRTC--VDINECVLDPGKCAPGTCQNLDGSYRCICP 2003
            NG C     S +C CN GY++  D +TC  +D++ C+ DP  C   TC + DG + C C 
Sbjct: 368  NGGCKIVGDSQECFCNTGYQLDGDNKTCIFIDVDWCLQDPSPCDQ-TCNSTDGKFTCGCF 192

Query: 2004 PGYSL 2008
             G+ L
Sbjct: 191  KGFQL 177

 Score = 42.4 bits (98), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 27/79 (34%), Positives = 38/79 (48%), Gaps = 2/79 (2%)
 Frame = -1

Query: 1162 ELSANLCPHGRCVNLIGKYQCACNPGYHPTHDRLFCV--DIDECSIMNGGCETFCTNSDG 1219
            EL  +L  +G C  +    +C CN GY    D   C+  D+D C      C+  C ++DG
Sbjct: 389  ELDCDL-DNGGCKIVGDSQECFCNTGYQLDGDNKTCIFIDVDWCLQDPSPCDQTCNSTDG 213

Query: 1220 SYECSCQPGFALMPDQRSC 1238
             + C C  GF L P  R+C
Sbjct: 212  KFTCGCFKGFQLNPGNRTC 156

 Score = 39.3 bits (90), Expect = 0.022,   Method: Compositional matrix adjust.
 Identities = 33/94 (35%), Positives = 45/94 (47%), Gaps = 4/94 (4%)
 Frame = -1

Query: 565 VTRDGKNCEDMDECSIRNMCL-NGMCINEDGSFKCICKPGFQLASDGRYCK--DINEC-E 620
           V  DG +CE    CS  +  L NG C     S +C C  G+QL  D + C   D++ C +
Sbjct: 434 VAMDGFSCETSTTCSELDCDLDNGGCKIVGDSQECFCNTGYQLDGDNKTCIFIDVDWCLQ 255

Query: 621 TPGICMNGRCVNTDGSYRCECFPGLAVGLDGRVC 654
            P  C +  C +TDG + C CF G  +    R C
Sbjct: 254 DPSPC-DQTCNSTDGKFTCGCFKGFQLNPGNRTC 156

 Score = 38.1 bits (87), Expect = 0.059,   Method: Compositional matrix adjust.
 Identities = 26/73 (35%), Positives = 33/73 (45%), Gaps = 2/73 (2%)
 Frame = -1

Query: 544 NNGRCINTDGSFHCVCNAGFHVTRDGKNC--EDMDECSIRNMCLNGMCINEDGSFKCICK 601
           +NG C     S  C CN G+ +  D K C   D+D C       +  C + DG F C C 
Sbjct: 371 DNGGCKIVGDSQECFCNTGYQLDGDNKTCIFIDVDWCLQDPSPCDQTCNSTDGKFTCGCF 192

Query: 602 PGFQLASDGRYCK 614
            GFQL    R C+
Sbjct: 191 KGFQLNPGNRTCR 153

 Score = 36.6 bits (83), Expect = 0.15,   Method: Compositional matrix adjust.
 Identities = 34/93 (36%), Positives = 43/93 (46%), Gaps = 4/93 (4%)
 Frame = -1

Query: 1440 SADGKACEDIDECS-LPNICVFGTCHNLPGLFRCECEIGYELDRSGGNCT--DVNECL-D 1495
            + DG +CE    CS L      G C  +     C C  GY+LD     C   DV+ CL D
Sbjct: 431  AMDGFSCETSTTCSELDCDLDNGGCKIVGDSQECFCNTGYQLDGDNKTCIFIDVDWCLQD 252

Query: 1496 PTTCISGNCVNTPGSYTCDCPPDFELNPTRVGC 1528
            P+ C    C +T G +TC C   F+LNP    C
Sbjct: 251  PSPCDQ-TCNSTDGKFTCGCFKGFQLNPGNRTC 156

 Score = 35.0 bits (79), Expect = 0.44,   Method: Compositional matrix adjust.
 Identities = 26/72 (36%), Positives = 34/72 (47%), Gaps = 4/72 (5%)
 Frame = -1

Query: 464 NGRCIPTPGSYRCECNKGFQLDIRGEC---IDVDECEKNPCTGGE-CINNQGSYTCHCRA 519
           NG C     S  C CN G+QLD   +    IDVD C ++P    + C +  G +TC C  
Sbjct: 368 NGGCKIVGDSQECFCNTGYQLDGDNKTCIFIDVDWCLQDPSPCDQTCNSTDGKFTCGCFK 189

Query: 520 GYQSTLTRTECR 531
           G+Q       CR
Sbjct: 188 GFQLNPGNRTCR 153

 Score = 34.7 bits (78), Expect = 0.57,   Method: Compositional matrix adjust.
 Identities = 26/84 (30%), Positives = 39/84 (46%), Gaps = 3/84 (3%)
 Frame = -1

Query: 1848 QCNDRNECQEIPNICSHGQCIDTVGSFYCLCHTGFKTNVDQTMC--LDINECERDACG-N 1904
             C     C E+     +G C     S  C C+TG++ + D   C  +D++ C +D    +
Sbjct: 416  SCETSTTCSELDCDLDNGGCKIVGDSQECFCNTGYQLDGDNKTCIFIDVDWCLQDPSPCD 237

Query: 1905 GTCRNTIGSFNCRCNHGFILSHNN 1928
             TC +T G F C C  GF L+  N
Sbjct: 236  QTCNSTDGKFTCGCFKGFQLNPGN 165

 Score = 34.3 bits (77), Expect = 0.84,   Method: Compositional matrix adjust.
 Identities = 18/53 (33%), Positives = 30/53 (56%), Gaps = 2/53 (3%)
 Frame = -1

Query: 2630 SYKCMCPTGFQYEQFSGGCQ--DINECGSSQAPCSYGCSNTEGGYLCGCPPGY 2680
            S +C C TG+Q +  +  C   D++ C    +PC   C++T+G + CGC  G+
Sbjct: 341  SQECFCNTGYQLDGDNKTCIFIDVDWCLQDPSPCDQTCNSTDGKFTCGCFKGF 183

 Score = 33.9 bits (76), Expect = 0.92,   Method: Compositional matrix adjust.
 Identities = 26/77 (33%), Positives = 34/77 (44%), Gaps = 2/77 (2%)
 Frame = -1

Query: 2259 DCTEKQMECKNLIGTYMCICGPGYQRRPDGEGC--IDENECQTKPGICENGRCLNTLGSY 2316
            DC      CK +  +  C C  GYQ   D + C  ID + C   P  C+   C +T G +
Sbjct: 383  DCDLDNGGCKIVGDSQECFCNTGYQLDGDNKTCIFIDVDWCLQDPSPCDQ-TCNSTDGKF 207

Query: 2317 TCECNDGFTASPTQDEC 2333
            TC C  GF  +P    C
Sbjct: 206  TCGCFKGFQLNPGNRTC 156

 Score = 33.5 bits (75), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 22/61 (36%), Positives = 32/61 (52%), Gaps = 1/61 (1%)
 Frame = -1

Query: 1096 ECKCDEGYE-SGFMMMKNCMDIDECQRDPLLCRGGICHNTEGSYRCECPPGHQLSPNISA 1154
            EC C+ GY+  G       +D+D C +DP  C    C++T+G + C C  G QL+P    
Sbjct: 335  ECFCNTGYQLDGDNKTCIFIDVDWCLQDPSPCDQ-TCNSTDGKFTCGCFKGFQLNPGNRT 159

Query: 1155 C 1155
            C
Sbjct: 158  C 156

 Score = 32.3 bits (72), Expect = 3.1,   Method: Compositional matrix adjust.
 Identities = 26/73 (35%), Positives = 34/73 (46%), Gaps = 4/73 (5%)
 Frame = -1

Query: 779 DNGQCRNTPGSFVCTCPKGFVYKPDLKTC--EDIDEC--ESSPCINGVCKNSPGSFICEC 834
           DNG C+    S  C C  G+    D KTC   D+D C  + SPC +  C ++ G F C C
Sbjct: 371 DNGGCKIVGDSQECFCNTGYQLDGDNKTCIFIDVDWCLQDPSPC-DQTCNSTDGKFTCGC 195

Query: 835 SPESTLDPTKTIC 847
                L+P    C
Sbjct: 194 FKGFQLNPGNRTC 156

 Score = 31.2 bits (69), Expect = 5.7,   Method: Compositional matrix adjust.
 Identities = 30/79 (37%), Positives = 39/79 (49%), Gaps = 3/79 (3%)
 Frame = -1

Query: 1612 CQELPGLCQGGKCINTFGSFQCRCPTGYYLNEDTRVC--DDVNEC-ETPGICGPGTCYNT 1668
            C EL      G C     S +C C TGY L+ D + C   DV+ C + P  C   TC +T
Sbjct: 395  CSELDCDLDNGGCKIVGDSQECFCNTGYQLDGDNKTCIFIDVDWCLQDPSPCDQ-TCNST 219

Query: 1669 VGNYTCICPPDYMQVNGGN 1687
             G +TC C   + Q+N GN
Sbjct: 218  DGKFTCGCFKGF-QLNPGN 165

 Score = 30.8 bits (68), Expect = 8.5,   Method: Compositional matrix adjust.
 Identities = 20/59 (33%), Positives = 25/59 (42%)
 Frame = -1

Query: 1590 LCPGGEGFRPNPITVILEDIDECQELPGLCQGGKCINTFGSFQCRCPTGYYLNEDTRVC 1648
             C  G     +  T I  D+D C + P  C    C +T G F C C  G+ LN   R C
Sbjct: 329  FCNTGYQLDGDNKTCIFIDVDWCLQDPSPCDQ-TCNSTDGKFTCGCFKGFQLNPGNRTC 156

 Score = 30.8 bits (68), Expect = 9.1,   Method: Compositional matrix adjust.
 Identities = 26/94 (27%), Positives = 38/94 (40%), Gaps = 2/94 (2%)
 Frame = -1

Query: 243 ACQDVDECQAIPGMCQGGNCINTVGSFECKCPAGHKFNEVSQKC--EDIDECSTIPGVCD 300
           +C+    C  +      G C     S EC C  G++ +  ++ C   D+D C   P  CD
Sbjct: 416 SCETSTTCSELDCDLDNGGCKIVGDSQECFCNTGYQLDGDNKTCIFIDVDWCLQDPSPCD 237

Query: 301 GGECTNTVSSYFCKCPPGFYTSPDGTRCVDVRPG 334
              C +T   + C C  GF  +P    C    PG
Sbjct: 236 -QTCNSTDGKFTCGCFKGFQLNPGNRTCRACSPG 138
>06474
          Length = 2466

 Score = 43.9 bits (102), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 48/168 (28%), Positives = 63/168 (37%), Gaps = 5/168 (2%)
 Frame = -1

Query: 464  NGRCIPTPGSYRCECNKGFQLDIRGECIDVDECEKNPCTGGECINNQGSYTCHCRAGYQS 523
            +G C  T  SY  + +    L + G     D    NPC         GS TC C +   +
Sbjct: 2076 SGTCTCTSASYTAKSDNTQCLSLIGVACTTD----NPCVTTAETCTAGSGTCSCASTKAT 1909

Query: 524  TLTRTECRDI--DECLQNGRICNNGRCINTDGSFHCVCNAGFHVTRDGKNCEDMDE--CS 579
            T  +TEC D   D C        NG C     S  C C +GF  + D K C  + +  CS
Sbjct: 1908 TYDKTECVDKVGDACSSAATCPTNGACT----SSLCACASGFTASTDNKQCVKLIDAACS 1741

Query: 580  IRNMC-LNGMCINEDGSFKCICKPGFQLASDGRYCKDINECETPGICM 626
              + C LN  C     S  C C  G+     G+ C    E     + M
Sbjct: 1740 SNSECPLNAQCT----SSTCSCDTGYTSDDGGKICSGAAEITASVLLM 1609

 Score = 38.9 bits (89), Expect = 0.032,   Method: Compositional matrix adjust.
 Identities = 62/221 (28%), Positives = 77/221 (34%), Gaps = 9/221 (4%)
 Frame = -1

Query: 1116 IDECQRDPLLCRGGICHNTEGSYRCECPPGHQLSPNISACIDI--NECELSANLCPHGRC 1173
             DEC      C G       GS  C C   +    + +AC  +    C   A   P G  
Sbjct: 2250 TDECVAGSAACPG------SGSTVCACDTNNVAKSDNTACYTLVGQTCATDAPCVP-GTD 2092

Query: 1174 VNLIGKYQCAC-NPGYHPTHDRLFCVDI--DECSIMNGGCETFCTNSDGSYECSCQPGFA 1230
                G   C C +  Y    D   C+ +    C+  N    T  T + GS  CSC    A
Sbjct: 2091 SCTAGSGTCTCTSASYTAKSDNTQCLSLIGVACTTDNPCVTTAETCTAGSGTCSCASTKA 1912

Query: 1231 LMPDQRSCTDI--DECEDNPNICDGGQCTNIPGEYRCLCYDGFMASEDMKTCVDV--NEC 1286
               D+  C D   D C         G CT+      C C  GF AS D K CV +    C
Sbjct: 1911 TTYDKTECVDKVGDACSSAATCPTNGACTS----SLCACASGFTASTDNKQCVKLIDAAC 1744

Query: 1287 DLNPNICLSGTCENTKGSFICHCDMGYSGKKGKTGCTDINE 1327
              N    L+  C     S  C CD GY+   G   C+   E
Sbjct: 1743 SSNSECPLNAQCT----SSTCSCDTGYTSDDGGKICSGAAE 1633

 Score = 31.2 bits (69), Expect = 6.8,   Method: Compositional matrix adjust.
 Identities = 32/129 (24%), Positives = 45/129 (34%), Gaps = 11/129 (8%)
 Frame = -1

Query: 2226 TYGSYECKC-PVGYVLREDRR--------MCKDEDECAEGKHDCTEKQMECKNLIGTYMC 2276
            T GS  C C    Y  + D           C  ++ C      CT          G+  C
Sbjct: 2085 TAGSGTCTCTSASYTAKSDNTQCLSLIGVACTTDNPCVTTAETCTA---------GSGTC 1933

Query: 2277 ICGPGYQRRPDGEGCIDE--NECQTKPGICENGRCLNTLGSYTCECNDGFTASPTQDECL 2334
             C        D   C+D+  + C +      NG C ++L    C C  GFTAS    +C+
Sbjct: 1932 SCASTKATTYDKTECVDKVGDACSSAATCPTNGACTSSL----CACASGFTASTDNKQCV 1765

Query: 2335 DNREGYCFS 2343
               +  C S
Sbjct: 1764 KLIDAACSS 1738

 Score = 30.8 bits (68), Expect = 8.5,   Method: Compositional matrix adjust.
 Identities = 31/101 (30%), Positives = 37/101 (36%), Gaps = 2/101 (1%)
 Frame = -1

Query: 265  TVGSFECKCPAGHKFNEVSQKCEDI--DECSTIPGVCDGGECTNTVSSYFCKCPPGFYTS 322
            T GS  C C +         +C D   D CS+       G CT    S  C C  GF  S
Sbjct: 1953 TAGSGTCSCASTKATTYDKTECVDKVGDACSSAATCPTNGACT----SSLCACASGFTAS 1786

Query: 323  PDGTRCVDVRPGYCYTALANGRCSNQLPQSITKMQCCCDLG 363
             D  +CV +    C    +N  C   L    T   C CD G
Sbjct: 1785 TDNKQCVKLIDAACS---SNSEC--PLNAQCTSSTCSCDTG 1678
>09839
          Length = 1599

 Score = 39.3 bits (90), Expect = 0.021,   Method: Compositional matrix adjust.
 Identities = 25/76 (32%), Positives = 42/76 (55%), Gaps = 1/76 (1%)
 Frame = +1

Query: 1325 INECEIGAHNCGRHAVCT-NTAGSFKCSCSPGWIGDGIKCTDLDECSNGTHMCSQHADCK 1383
            I+ C+  A+ C  +A C+ +  G+ +CSC+  + GDG  CT + + + G   C   ADC 
Sbjct: 886  ISLCQTSANTCSTNAGCSVDNTGTVQCSCNANYQGDGTTCTHVCDVAGG--YCQNGADCV 1059

Query: 1384 NTMGSYRCLCKDGYTG 1399
              + +  C+CK  Y+G
Sbjct: 1060 KNLAA-PCVCKQFYSG 1104
>17529
          Length = 457

 Score = 38.9 bits (89), Expect = 0.031,   Method: Compositional matrix adjust.
 Identities = 24/58 (41%), Positives = 28/58 (48%)
 Frame = -1

Query: 83  PICRHSCGDGFCSRPNMCTCPSGQISPSCGSRSIQHCSIRCMNGGSCSDDHCLCQKGY 140
           P+C   CG G C  PN C C  G      GS    +C +RC NG   +   CLCQ GY
Sbjct: 448 PMCIPDCGYGHCVAPNQCECFPGFKKRMNGSSCEGNCYMRCENGFCANQTTCLCQNGY 275
>32228
          Length = 1295

 Score = 38.1 bits (87), Expect = 0.053,   Method: Compositional matrix adjust.
 Identities = 21/47 (44%), Positives = 28/47 (59%)
 Frame = -3

Query: 1970 GRTCVDINECVLDPGKCAPGTCQNLDGSYRCICPPGYSLQNDKCEDI 2016
            G+ C   N C  +P  C PGTC +  G +RC+CPPG  +   KCED+
Sbjct: 459  GQGCSAPNAC--EPNPCGPGTCVDEWGHHRCLCPPG--MIGPKCEDV 331

 Score = 33.9 bits (76), Expect = 0.94,   Method: Compositional matrix adjust.
 Identities = 16/34 (47%), Positives = 21/34 (61%)
 Frame = -3

Query: 1648 CDDVNECETPGICGPGTCYNTVGNYTCICPPDYM 1681
            C   N CE P  CGPGTC +  G++ C+CPP  +
Sbjct: 450  CSAPNACE-PNPCGPGTCVDEWGHHRCLCPPGMI 352

 Score = 32.3 bits (72), Expect = 3.1,   Method: Compositional matrix adjust.
 Identities = 21/65 (32%), Positives = 30/65 (46%)
 Frame = -3

Query: 566 TRDGKNCEDMDECSIRNMCLNGMCINEDGSFKCICKPGFQLASDGRYCKDINECETPGIC 625
           T  G+ C   + C   N C  G C++E G  +C+C PG         C++ N CE  G+C
Sbjct: 468 TNVGQGCSAPNACE-PNPCGPGTCVDEWGHHRCLCPPGMIGPKCEDVCREYNPCENWGVC 292

Query: 626 MNGRC 630
              R 
Sbjct: 291 ERPRA 277

 Score = 31.2 bits (69), Expect = 5.6,   Method: Compositional matrix adjust.
 Identities = 30/120 (25%), Positives = 49/120 (40%), Gaps = 7/120 (5%)
 Frame = -3

Query: 1710 GELLFNMTKKMCCCSYNIGRAWNKPCEQCPIPSTDEFATLCGSQRPGFVIDIYTGLPVDI 1769
            G++  ++T        +I R +     Q   P +D F+      R G  ++     PV+ 
Sbjct: 645  GQIEKSITLTQSVSGSDIQRIYVGGYRQGNEPISDGFSGCVKDIRVGNNMNALLNNPVET 466

Query: 1770 DECR--EIPGVCEN-----GVCINMVGSFRCECPVGFFYNDKLLVCEDIDECQNGPVCQR 1822
            +  +    P  CE      G C++  G  RC CP G        VC + + C+N  VC+R
Sbjct: 465  NVGQGCSAPNACEPNPCGPGTCVDEWGHHRCLCPPGMIGPKCEDVCREYNPCENWGVCER 286
>36274
          Length = 367

 Score = 37.0 bits (84), Expect = 0.11,   Method: Composition-based stats.
 Identities = 15/28 (53%), Positives = 16/28 (57%)
 Frame = +3

Query: 1820 CQRNAECINTAGSYRCDCKPGYRLTSTG 1847
            C RNA C NT GSY C C PG+   S  
Sbjct: 237  CGRNANCFNTEGSYLCVCHPGFDXNSAA 320

 Score = 35.4 bits (80), Expect = 0.31,   Method: Composition-based stats.
 Identities = 14/26 (53%), Positives = 18/26 (69%)
 Frame = +3

Query: 1331 GAHNCGRHAVCTNTAGSFKCSCSPGW 1356
            G + CGR+A C NT GS+ C C PG+
Sbjct: 225  GDNTCGRNANCFNTEGSYLCVCHPGF 302

 Score = 26.2 bits (56), Expect(2) = 1.5,   Method: Composition-based stats.
 Identities = 10/20 (50%), Positives = 12/20 (60%)
 Frame = +3

Query: 463 QNGRCIPTPGSYRCECNKGF 482
           +N  C  T GSY C C+ GF
Sbjct: 243 RNANCFNTEGSYLCVCHPGF 302

 Score = 25.4 bits (54), Expect(2) = 1.5,   Method: Compositional matrix adjust.
 Identities = 10/19 (52%), Positives = 14/19 (73%)
 Frame = +2

Query: 479 NKGFQLDIRGECIDVDECE 497
           + G    +RG+C+DVDECE
Sbjct: 290 SSGL*XKLRGDCVDVDECE 346

 Score = 33.1 bits (74), Expect = 1.8,   Method: Composition-based stats.
 Identities = 12/28 (42%), Positives = 20/28 (71%)
 Frame = +3

Query: 1370 SNGTHMCSQHADCKNTMGSYRCLCKDGY 1397
            ++G + C ++A+C NT GSY C+C  G+
Sbjct: 219  NDGDNTCGRNANCFNTEGSYLCVCHPGF 302

 Score = 32.0 bits (71), Expect = 3.6,   Method: Composition-based stats.
 Identities = 16/35 (45%), Positives = 19/35 (54%)
 Frame = +3

Query: 1488 TDVNECLDPTTCISGNCVNTPGSYTCDCPPDFELN 1522
            T+V    D T   + NC NT GSY C C P F+ N
Sbjct: 207  TNVANDGDNTCGRNANCFNTEGSYLCVCHPGFDXN 311

 Score = 28.9 bits (63), Expect(2) = 4.4,   Method: Composition-based stats.
 Identities = 10/16 (62%), Positives = 12/16 (75%)
 Frame = +3

Query: 1214 CTNSDGSYECSCQPGF 1229
            C N++GSY C C PGF
Sbjct: 255  CFNTEGSYLCVCHPGF 302

 Score = 21.2 bits (43), Expect(2) = 4.4,   Method: Compositional matrix adjust.
 Identities = 8/14 (57%), Positives = 10/14 (71%)
 Frame = +2

Query: 1238 CTDIDECEDNPNIC 1251
            C D+DECED  + C
Sbjct: 323  CVDVDECEDYSHKC 364

 Score = 31.6 bits (70), Expect = 5.2,   Method: Composition-based stats.
 Identities = 14/36 (38%), Positives = 19/36 (52%)
 Frame = +3

Query: 627 NGRCVNTDGSYRCECFPGLAVGLDGRVCVDTHMRST 662
           N  C NT+GSY C C PG        V + T +++T
Sbjct: 246 NANCFNTEGSYLCVCHPGFDXNSAATVSMWTSVKTT 353

 Score = 31.2 bits (69), Expect = 7.0,   Method: Composition-based stats.
 Identities = 13/34 (38%), Positives = 19/34 (55%), Gaps = 1/34 (2%)
 Frame = +3

Query: 1860 NICS-HGQCIDTVGSFYCLCHTGFKTNVDQTMCL 1892
            N C  +  C +T GS+ C+CH GF  N   T+ +
Sbjct: 231  NTCGRNANCFNTEGSYLCVCHPGFDXNSAATVSM 332

 Score = 30.8 bits (68), Expect = 8.6,   Method: Composition-based stats.
 Identities = 11/19 (57%), Positives = 14/19 (73%)
 Frame = +3

Query: 545 NGRCINTDGSFHCVCNAGF 563
           N  C NT+GS+ CVC+ GF
Sbjct: 246 NANCFNTEGSYLCVCHPGF 302

 Score = 30.8 bits (68), Expect = 9.1,   Method: Composition-based stats.
 Identities = 11/23 (47%), Positives = 14/23 (60%)
 Frame = +3

Query: 586 NGMCINEDGSFKCICKPGFQLAS 608
           N  C N +GS+ C+C PGF   S
Sbjct: 246 NANCFNTEGSYLCVCHPGFDXNS 314
>37574
          Length = 433

 Score = 37.0 bits (84), Expect = 0.13,   Method: Compositional matrix adjust.
 Identities = 30/88 (34%), Positives = 34/88 (38%)
 Frame = -3

Query: 73  TLPGGNQCIVPICRHSCGDGFCSRPNMCTCPSGQISPSCGSRSIQHCSIRCMNGGSCSDD 132
           T   G  C   +CR  C  G C R   C C  G     C       C  RC   G CS+ 
Sbjct: 263 TAFTGPDCETEVCRLVCVHGHC-RNQRCVCAQGWTGALCDQLQ---CDRRCHAHGFCSNG 96

Query: 133 HCLCQKGYIGTHCGQPVCESGCLNGGRC 160
            C+C KG+ G HC    C   C   G C
Sbjct: 95  SCVCDKGWNGKHCTINGCPKDCSGHGEC 12
>08033
          Length = 1035

 Score = 36.6 bits (83), Expect = 0.15,   Method: Compositional matrix adjust.
 Identities = 16/35 (45%), Positives = 23/35 (65%), Gaps = 2/35 (5%)
 Frame = -1

Query: 725  DINECALDPDICPNG--ICENLRGTYKCICNSGYE 757
            ++NEC    D+CPN   ICE+  G+Y+C+C S  E
Sbjct: 1011 NVNECFFSSDLCPNDFEICEDTEGSYRCVCTSQAE 907
>00070
          Length = 1809

 Score = 36.2 bits (82), Expect = 0.19,   Method: Compositional matrix adjust.
 Identities = 43/135 (31%), Positives = 56/135 (41%), Gaps = 13/135 (9%)
 Frame = +1

Query: 1934 DECATG---NGNLCRNGQCVNTVGSFQCRCNEGYEVAPDGRTCVDINECVLDPGKCAPGT 1990
            D CA+    NG  C        +  F+C C +GY     G TC   ++ V   G CA   
Sbjct: 139  DVCASSPCKNGAKCSVQVTRARLSLFKCTCAKGY----SGETC---DQSVDTSGACASRP 297

Query: 1991 CQN-------LDGSYRCICPPGYSLQNDKCEDIDECVEEP--EICALGTCSNTE-GSFKC 2040
            CQN         GS++C CP  Y  Q D CE     V  P  +     T +NT     KC
Sbjct: 298  CQNGGSCKPTSYGSFKCTCPALY--QGDSCEIKSAWVNSPCGDTGVACTGANTVCFKGKC 471

Query: 2041 LCPEGFSLSSTGRRC 2055
            LC  G+  S + + C
Sbjct: 472  LCTPGYHYSVSSQTC 516
>33353
          Length = 559

 Score = 34.3 bits (77), Expect = 0.74,   Method: Compositional matrix adjust.
 Identities = 18/35 (51%), Positives = 20/35 (57%), Gaps = 1/35 (2%)
 Frame = -2

Query: 488 GECIDVDECEKNPC-TGGECINNQGSYTCHCRAGY 521
             C D   C +NPC  GG CI   G+YTC CR GY
Sbjct: 555 ASCKDDGVCAENPCRNGGTCIPGIGTYTCQCRQGY 451
>14910
          Length = 1374

 Score = 33.9 bits (76), Expect = 0.88,   Method: Compositional matrix adjust.
 Identities = 28/75 (37%), Positives = 33/75 (44%), Gaps = 7/75 (9%)
 Frame = -3

Query: 1956 FQCRCNEGYEVAPDGRTCVDINECVLDPGKCAPGTCQN-------LDGSYRCICPPGYSL 2008
            F+C C EGY     G TC   ++ V   G C+   CQN         GSY+C CP  Y  
Sbjct: 307  FKCTCAEGYS----GETC---DQTVDTSGACSSRPCQNGGSCKPTSYGSYKCTCPALY-- 155

Query: 2009 QNDKCEDIDECVEEP 2023
            Q D CE     V  P
Sbjct: 154  QGDSCEIKSAWVNSP 110

 Score = 30.4 bits (67), Expect = 9.9,   Method: Compositional matrix adjust.
 Identities = 26/76 (34%), Positives = 39/76 (51%), Gaps = 3/76 (3%)
 Frame = -3

Query: 2590 YRCSCPQGYLQHYQWNQCVDENECLSAHVC-GGASCHNT-LGSYKCMCPTGFQYEQFSGG 2647
            ++C+C +GY      +Q VD +   S+  C  G SC  T  GSYKC CP  +Q +     
Sbjct: 307  FKCTCAEGYSGE-TCDQTVDTSGACSSRPCQNGGSCKPTSYGSYKCTCPALYQGDSCEIK 131

Query: 2648 CQDINE-CGSSQAPCS 2662
               +N  CG ++A C+
Sbjct: 130  SAWVNSPCGDAEAGCT 83
>05519
          Length = 1164

 Score = 33.1 bits (74), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 33/100 (33%), Positives = 41/100 (41%), Gaps = 10/100 (10%)
 Frame = -2

Query: 1934 DECATG---NGNLCRNGQCVNTVGSFQCRCNEGYEVAPDGRTCVDINECVLDPGKCAPGT 1990
            D CA+    NG  C        +  F+C C +GY     G TC   ++ V   G CA   
Sbjct: 308  DVCASSPCKNGAKCSVQVTRARLSLFKCTCAKGYS----GETC---DQSVDTSGACASRP 150

Query: 1991 CQN-------LDGSYRCICPPGYSLQNDKCEDIDECVEEP 2023
            CQN         GS++C CP  Y  Q D CE     V  P
Sbjct: 149  CQNGGSCKPTSYGSFKCTCPALY--QGDSCEIKSAWVNSP 36
>03995
          Length = 944

 Score = 33.1 bits (74), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 17/38 (44%), Positives = 23/38 (60%), Gaps = 2/38 (5%)
 Frame = -1

Query: 2461 CKNTEGSYQCSCPKGYILQEDGRSCKDLD--ECATKQH 2496
            C+N+ GS+ C+C  G  L EDG+SCK       AT +H
Sbjct: 932  CRNSVGSFACTCSAGSSLAEDGKSCKRSSCPTLATPRH 819

 Score = 32.0 bits (71), Expect = 3.5,   Method: Compositional matrix adjust.
 Identities = 14/27 (51%), Positives = 19/27 (70%)
 Frame = -1

Query: 1947 GQCVNTVGSFQCRCNEGYEVAPDGRTC 1973
            G C N+VGSF C C+ G  +A DG++C
Sbjct: 938  GGCRNSVGSFACTCSAGSSLAEDGKSC 858

 Score = 31.6 bits (70), Expect = 4.8,   Method: Compositional matrix adjust.
 Identities = 18/45 (40%), Positives = 23/45 (51%)
 Frame = -1

Query: 587 GMCINEDGSFKCICKPGFQLASDGRYCKDINECETPGICMNGRCV 631
           G C N  GSF C C  G  LA DG+ CK  + C T     +G+ +
Sbjct: 938 GGCRNSVGSFACTCSAGSSLAEDGKSCKR-SSCPTLATPRHGQVI 807

 Score = 31.6 bits (70), Expect = 5.0,   Method: Compositional matrix adjust.
 Identities = 31/109 (28%), Positives = 42/109 (38%), Gaps = 19/109 (17%)
 Frame = -1

Query: 1905 GTCRNTIGSFNCRCNHGFILSHNNDCIDVDECATGNGNLCRNGQCV-------------- 1950
            G CRN++GSF C C+ G  L+ +        C T      R+GQ +              
Sbjct: 938  GGCRNSVGSFACTCSAGSSLAEDGKSCKRSSCPTLATP--RHGQVIPVQCRMTPRAGQHA 765

Query: 1951 ----NTVGSFQCRCNEGYEVA-PDGRTCVDINECVLDPGKCAPGTCQNL 1994
                 TV S++CR   G+ +  P  RTC            C P TC  L
Sbjct: 764  WLTPETVCSYRCR--RGFTLTGPAYRTCQSNGTWTGSEPTCTPKTCGKL 624

 Score = 31.2 bits (69), Expect = 6.0,   Method: Compositional matrix adjust.
 Identities = 14/28 (50%), Positives = 19/28 (67%)
 Frame = -1

Query: 546 GRCINTDGSFHCVCNAGFHVTRDGKNCE 573
           G C N+ GSF C C+AG  +  DGK+C+
Sbjct: 938 GGCRNSVGSFACTCSAGSSLAEDGKSCK 855
>18717
          Length = 853

 Score = 32.0 bits (71), Expect = 4.1,   Method: Compositional matrix adjust.
 Identities = 30/106 (28%), Positives = 44/106 (41%), Gaps = 12/106 (11%)
 Frame = +3

Query: 1426 PGGYRCECDMGF-------VPSAD-GKACEDIDECSLPNICVFGTCHNLPGLFR----CE 1473
            P G RC CD+G+       +PS + GK C    +C     C+ G C      +R    C 
Sbjct: 276  PHGGRCTCDLGYYAAHHECLPSVEVGKPCSGKGQCITNAKCIAGQCRCTEDYYRYGKMCR 455

Query: 1474 CEIGYELDRSGGNCTDVNECLDPTTCISGNCVNTPGSYTCDCPPDF 1519
              +G     SG  CT + +C+  + C      ++P    C C  DF
Sbjct: 456  KRVG-----SGDTCTGLGQCVADSEC------SSPVRGKCQCGNDF 560
>09979
          Length = 1785

 Score = 31.6 bits (70), Expect = 5.0,   Method: Compositional matrix adjust.
 Identities = 24/75 (32%), Positives = 39/75 (52%), Gaps = 2/75 (2%)
 Frame = +3

Query: 1328 CEIGAHNCGRHAVCTNTAGSFKCSCSPGWIGDGIKCTDLDE--CSNGTHMCSQHADCKNT 1385
            C +G  +CG ++ C + AG+ KC+C   ++ +  +C    E  CS  +  C  +A+C  T
Sbjct: 276  CNVG--DCGVNSECKDDAGTKKCACKADFVDENGRCGMAAEGSCSINSD-CVTNAECTGT 446

Query: 1386 MGSYRCLCKDGYTGD 1400
                +C CK  YT D
Sbjct: 447  GNDKKCSCKADYTAD 491
>12472
          Length = 844

 Score = 31.6 bits (70), Expect = 5.2,   Method: Compositional matrix adjust.
 Identities = 32/110 (29%), Positives = 43/110 (39%), Gaps = 5/110 (4%)
 Frame = +2

Query: 1787 MVGSFRCECPVGFFYNDKLLVCEDIDECQNGPVCQRNAEC-INTAGSYRCDCKPGYRLTS 1845
              GS  C C  G   +D   +C  +     G  C   ++C  N A S  C C  G+  +S
Sbjct: 134  TAGSGTCSCASGKVASDDNKLCVILI----GSACSATSDCPTNAACSTBCGCNSGFTASS 301

Query: 1846 TGQCNDRNEC-QEIPNICSHGQCIDTVG---SFYCLCHTGFKTNVDQTMC 1891
                 D  +C ++I   CS        G   S  C C TG+  N D T C
Sbjct: 302  -----DNKQCVKKITEACSABSECPIFGVCTSSICACSTGYTANSDNTKC 436

 Score = 30.8 bits (68), Expect = 9.2,   Method: Compositional matrix adjust.
 Identities = 43/156 (27%), Positives = 53/156 (33%), Gaps = 10/156 (6%)
 Frame = +2

Query: 1178 GKYQCACNPGYHPTH-DRLFCVDI--DECSIMNGGCETFCTNSDGSYECSCQPGFALMPD 1234
            G   CAC    H    D   C+ +    C+  +    T  T + GS  CSC  G     D
Sbjct: 8    GSGTCACETTTHVAKXDNTQCLALIGQPCTTTHPCVXTADTCTAGSGTCSCASGKVASDD 187

Query: 1235 QRSCTDI-----DECEDNPNICDGGQCTNIPGEYRCLCYDGFMASEDMKTCVD--VNECD 1287
             + C  +         D P        TN      C C  GF AS D K CV      C 
Sbjct: 188  NKLCVILIGSACSATSDCP--------TNAACSTBCGCNSGFTASSDNKQCVKKITEACS 343

Query: 1288 LNPNICLSGTCENTKGSFICHCDMGYSGKKGKTGCT 1323
             +    + G C     S IC C  GY+     T C+
Sbjct: 344  ABSECPIFGVCT----SSICACSTGYTANSDNTKCS 439
>00974
          Length = 1935

 Score = 31.2 bits (69), Expect = 5.9,   Method: Compositional matrix adjust.
 Identities = 18/59 (30%), Positives = 25/59 (42%), Gaps = 1/59 (1%)
 Frame = +1

Query: 2098 CELCPTEPDEAFRQICPFGSGIIVGPDDSAVDMDECK-EPDVCRHGQCINTDGSYRCEC 2155
            CE+   E  EA    C     +I+  + S  D++ C  +PD C   QC    G    EC
Sbjct: 1510 CEVATYEWIEALWWGCILRETVIIHKNSSKYDVNYCACDPDYCHFVQCSLNTGIVHAEC 1686
>31203
          Length = 1813

 Score = 31.2 bits (69), Expect = 6.2,   Method: Compositional matrix adjust.
 Identities = 66/245 (26%), Positives = 91/245 (37%), Gaps = 52/245 (21%)
 Frame = -3

Query: 453 DYCQLVRYLCQNGRCIPTPGSYRCECNKGFQLDIRGECIDVDECEKNPCTGG-ECINNQ- 510
           D C  +R   +N  C    G   CECN GF +D + +CI   +   NPC    +C++N  
Sbjct: 857 DPCSGLRECVENAECTTAMGGL-CECNDGFYIDNK-KCIPSIKVH-NPCVETLQCVSNAV 687

Query: 511 ---GSYTCHCRAGYQSTLTRTECRDI--DECLQNGRICNNGRCINTDGSFHCVCNAGFH- 564
               + TC CR  Y       E +    + C   G+  +N  C +  G   C+C+ GF  
Sbjct: 686 CTPETGTCECRDDYFPLKGNCEKKKKASEPCGGYGQCVDNAECNSPQGGL-CLCHEGFFE 510

Query: 565 -------VTRDGKNCEDMDEC---------------------------------SIRNMC 584
                   T  GK C   +EC                                 S  +MC
Sbjct: 509 NDGACRTQTELGKACTGEEECTPNSVCVETCRCREGYFKDKGLCYEKKLVGDPCSFDDMC 330

Query: 585 -LNGMCINEDGSFKCICKPGF--QLASDGRYCKDINECETPGIC-MNGRCVNTDGSYRCE 640
            L  +C +E   F CIC+ GF  Q    G       EC+  G C +N  C N  G   C+
Sbjct: 329 SLWMICSSEINGF-CICQDGFFEQNRQCGGRIPPGEECQELGACVINAECSNPSGGI-CQ 156

Query: 641 CFPGL 645
           C P  
Sbjct: 155 CLPDF 141
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|13385270|ref|NP_080074.1| histidine triad nucleotide
binding protein 3 [Mus musculus]
         (165 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

15997                                                                 108   6e-26
09321                                                                  27   3.7  
04010                                                                  27   4.1  
26918                                                                  26   5.9  
01620                                                                  26   5.9  
38469                                                                  26   6.8  
>15997
          Length = 652

 Score =  108 bits (269), Expect(2) = 6e-26,   Method: Compositional matrix adjust.
 Identities = 52/113 (46%), Positives = 73/113 (64%)
 Frame = +2

Query: 31  CVFCRVAAGQEPKTELFHCENEDLVCFKDIKPAALYHYLVVPKKHIGSCKDLNKDHIEMV 90
           C+FCR+A G E  T L + + + +V FKDI+PAA +HYLVVPK HI   K L      ++
Sbjct: 155 CLFCRIANGXENSTRLLY-DQDGIVIFKDIRPAASHHYLVVPKTHIKDAKHLTVKDTPLL 331

Query: 91  ESMVAAGKTMLERNNFTDFTDVRMGFHVPPFCSISHLHLHVIAPVKEFGFLSK 143
           E +V  G   L++    D  + RMGFH PPF S++HLHLHVI+P  E G++++
Sbjct: 332 EQLVKVGTEFLQQQGGDD-KNARMGFHWPPFHSVAHLHLHVISPQSEMGWVAR 487

 Score = 25.0 bits (53), Expect(2) = 6e-26,   Method: Compositional matrix adjust.
 Identities = 9/19 (47%), Positives = 14/19 (73%)
 Frame = +3

Query: 145 VYRQDSYWFVTVDYLLEKL 163
           VY+ DS+WF T  ++L +L
Sbjct: 492 VYKSDSWWFKTPHWVLGRL 548
>09321
          Length = 1284

 Score = 26.9 bits (58), Expect = 3.7,   Method: Compositional matrix adjust.
 Identities = 19/54 (35%), Positives = 30/54 (55%), Gaps = 1/54 (1%)
 Frame = +3

Query: 104 NNFTDFTDVRMGFHVPPFCSISHLHLHVIAPVKEFGFLS-KLVYRQDSYWFVTV 156
           NNF  F+   +G       SI ++++ V A V E+  L  K+VY +DSY+ V +
Sbjct: 564 NNFVCFSG-HVGL*PKQL*SIFNIYVCVCACVCEYSVLVIKIVYHKDSYFLVIL 722
>04010
          Length = 1992

 Score = 26.9 bits (58), Expect = 4.1,   Method: Compositional matrix adjust.
 Identities = 12/34 (35%), Positives = 19/34 (55%)
 Frame = +3

Query: 81  DLNKDHIEMVESMVAAGKTMLERNNFTDFTDVRM 114
           D +  + EM ESM + GKT   +++   FTD  +
Sbjct: 486 DFSDSYPEMSESMGSVGKTEATQSSVISFTDANL 587
>26918
          Length = 555

 Score = 26.2 bits (56), Expect = 5.9,   Method: Compositional matrix adjust.
 Identities = 11/27 (40%), Positives = 15/27 (55%)
 Frame = -2

Query: 64  ALYHYLVVPKKHIGSCKDLNKDHIEMV 90
             +H+L V K  +  CK L +DHI  V
Sbjct: 428 VFFHFLTVGKSSLFVCKFLRRDHIHGV 348
>01620
          Length = 3837

 Score = 26.2 bits (56), Expect = 5.9,   Method: Compositional matrix adjust.
 Identities = 19/57 (33%), Positives = 28/57 (49%)
 Frame = -2

Query: 28   DSNCVFCRVAAGQEPKTELFHCENEDLVCFKDIKPAALYHYLVVPKKHIGSCKDLNK 84
             S C F  V +GQ    ELF C +E  V    +  A+L+  + + +  + SC  LNK
Sbjct: 2246 TSICTFPPVVSGQN---ELFECCSEVWVTMVXVDTASLWPSVCLLQFCLCSCL*LNK 2085
>38469
          Length = 528

 Score = 26.2 bits (56), Expect = 6.8,   Method: Compositional matrix adjust.
 Identities = 11/35 (31%), Positives = 17/35 (48%)
 Frame = -2

Query: 36  VAAGQEPKTELFHCENEDLVCFKDIKPAALYHYLV 70
           VA    P+  L HC  +  +C   +KP   +H +V
Sbjct: 308 VAFKHFPQLYLGHCSTKSCIC*TSLKPQLAWHNMV 204
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|9789913|ref|NP_062791.1| coatomer protein complex,
subunit zeta 1 [Mus musculus]
         (177 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

31373                                                                 112   6e-26
18687                                                                  50   7e-07
04375                                                                  35   0.018
18107                                                                  27   5.5  
>31373
          Length = 314

 Score =  112 bits (281), Expect = 6e-26,   Method: Compositional matrix adjust.
 Identities = 50/72 (69%), Positives = 64/72 (88%)
 Frame = -2

Query: 106 RKNVEKRALLENMEGLFLAVDEIVDGGVILESDPQQVVHRVALRGEDVPLTEQTVSQVLQ 165
           RKNVEKRALL+NM+ +FLA DEI DGG++LE++P  +V +VA+R +D+PL EQTV+QVLQ
Sbjct: 313 RKNVEKRALLDNMDAVFLAADEICDGGILLEAEPNAIVTKVAIRNDDIPLGEQTVAQVLQ 134

Query: 166 SAKEQIKWSLLR 177
           SAKEQIKWSLL+
Sbjct: 133 SAKEQIKWSLLK 98
>18687
          Length = 778

 Score = 49.7 bits (117), Expect = 7e-07,   Method: Compositional matrix adjust.
 Identities = 22/27 (81%), Positives = 26/27 (96%)
 Frame = +2

Query: 151 EDVPLTEQTVSQVLQSAKEQIKWSLLR 177
           +D+PL EQTV+QVLQSAKEQIKWSLL+
Sbjct: 5   DDIPLGEQTVAQVLQSAKEQIKWSLLK 85
>04375
          Length = 2667

 Score = 35.0 bits (79), Expect = 0.018,   Method: Compositional matrix adjust.
 Identities = 26/94 (27%), Positives = 44/94 (46%), Gaps = 4/94 (4%)
 Frame = +3

Query: 65  LTVVYKSSIDLYFYVIGSSYENELMLMAVLNCLFDSLSQMLRKNVEKRALLENMEGLFLA 124
           L VVYK    LYF       +NEL+ + +++   + L +      E   +  N E  F  
Sbjct: 264 LKVVYKRYASLYFCCAIEPEDNELLTLEIIHRYVELLDKYFGSVCELDIIF-NFEKAFFM 440

Query: 125 VDEIVDGGVILESDPQQVVHRVA----LRGEDVP 154
           +DE + GG + E+  + V+  +A    L+ E+ P
Sbjct: 441 LDEFMLGGEVQETSKKNVLKAIAAQDLLQEEETP 542
>18107
          Length = 668

 Score = 26.6 bits (57), Expect = 5.5,   Method: Compositional matrix adjust.
 Identities = 17/56 (30%), Positives = 27/56 (48%), Gaps = 11/56 (19%)
 Frame = -3

Query: 90  LMAVLNCLFDSLSQMLRKNVEKRALLENMEGLFLAVD-----------EIVDGGVI 134
           ++ VL+C  D+   ++  +V K  L + + GLF A D           E+ D GVI
Sbjct: 390 VILVLSCFEDTFDLLIGSDVSKPLLSKQISGLFRAKDIPASS*FKISFEVFDNGVI 223
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|11230782|ref|NP_068685.1| tubby [Mus musculus]
         (505 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

29211                                                                  69   7e-26
08961                                                                  29   3.9  
>29211
          Length = 396

 Score = 68.9 bits (167), Expect(3) = 7e-26,   Method: Composition-based stats.
 Identities = 34/58 (58%), Positives = 42/58 (72%)
 Frame = +2

Query: 326 SYIGKLRSNLMGTKFTVYDNGVNPQKASSSTLESGTLRQELAAVCYETNVLGFKGPRK 383
           S + KLRSN++GT FT+++NG NP+K +         RQEL AV YETNVLGFKGPRK
Sbjct: 104 SLLWKLRSNMLGTHFTLFNNGDNPKKNAQDA------RQELVAVAYETNVLGFKGPRK 259

 Score = 47.0 bits (110), Expect(3) = 7e-26,   Method: Compositional matrix adjust.
 Identities = 22/40 (55%), Positives = 30/40 (75%)
 Frame = +3

Query: 290 EDGKKVFLLAGRKRKKSKTSNYLISVDPTDLSRGGDSYIG 329
           EDGK     A  +++KS+TSNYL+S DPTDLSR G+++ G
Sbjct: 6   EDGKNP---ASGQKRKSRTSNYLMSTDPTDLSRNGEAFCG 116

 Score = 39.7 bits (91), Expect(3) = 7e-26,   Method: Compositional matrix adjust.
 Identities = 15/34 (44%), Positives = 24/34 (70%)
 Frame = +1

Query: 377 GFKGPRKMSVIVPGMNMVHERVCIRPRNEHETLL 410
           G +G +KM++I+PGM   H+RV I P+  H+ L+
Sbjct: 238 GLQGSKKMTIIIPGMTSDHKRVDITPKGNHDGLI 339
>08961
          Length = 2948

 Score = 29.3 bits (64), Expect = 3.9,   Method: Compositional matrix adjust.
 Identities = 14/49 (28%), Positives = 25/49 (51%)
 Frame = +3

Query: 429  PVWNDDTQSYVLNFHGRVTQASVKNFQIIHGNDPDYIVMQFGRVAEDVF 477
            P W++ + S VL++HGR     + +F + H     ++   F   AE +F
Sbjct: 2712 PSWSESSHSLVLDYHGRF----LLSFDVFHSCVTYFVASNFLGDAECLF 2846
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|188219614|ref|NP_035800.2| ubiquitin carboxy-terminal
hydrolase L1 [Mus musculus]
         (223 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

18699                                                                 113   7e-26
10106                                                                  61   4e-10
30672                                                                  29   1.3  
24758                                                                  27   5.0  
>18699
          Length = 601

 Score =  113 bits (282), Expect = 7e-26,   Method: Compositional matrix adjust.
 Identities = 54/121 (44%), Positives = 75/121 (61%)
 Frame = -3

Query: 10  PEMLNKVLAKLGVAGQWRFADVLGLEEETLGSVPSPACALLLLFPLTAQHENFRKKQIEE 69
           P +LNK L  LGV+ +W+F D+ GLE E L  VP P  A++LL+PLT   +     +I  
Sbjct: 593 PTVLNKYLGNLGVSKEWQFVDIYGLEPELLSMVPKPVAAVMLLYPLT---DKVDAAKIGT 423

Query: 70  LKGQEVSPKVYFMKQTIGNSCGTIGLIHAVANNQDKLEFEDGSVLKQFLSETEKLSPEDR 129
              +  +  VYFMKQ+I N+CGT+ L+HA+ANN+  + FED    K FL  T+ LSPE +
Sbjct: 422 EDAEYNAESVYFMKQSISNACGTVALVHALANNEKHIXFEDDKHFKVFLENTKGLSPEKK 243

Query: 130 A 130
            
Sbjct: 242 G 240

 Score = 75.1 bits (183), Expect = 2e-14,   Method: Compositional matrix adjust.
 Identities = 40/91 (43%), Positives = 55/91 (60%), Gaps = 3/91 (3%)
 Frame = -2

Query: 120 ETEKLSPEDRAKCFEKNEAIQAAHDSVAQEGQCRV---DDKVNFHFILFNNVDGHLYELD 176
           E + L    +    E++E + A H+  A EG  +    D KVN HFI F +VDG LYE+D
Sbjct: 273 EHQGLESRKKGAHLEQDEKMGAVHEENALEGDTQAPSRDTKVNPHFISFVHVDGTLYEMD 94

Query: 177 GRMPFPVNHGASSEDSLLQDAAKVCREFTER 207
           GR   PVNHG +S D+LL++AA V ++F  R
Sbjct: 93  GRKDAPVNHGPTSADNLLENAAAVAKKFMTR 1
>10106
          Length = 1115

 Score = 60.8 bits (146), Expect = 4e-10,   Method: Compositional matrix adjust.
 Identities = 50/227 (22%), Positives = 99/227 (43%), Gaps = 12/227 (5%)
 Frame = +2

Query: 6   MEINPEMLNKVLAKLGVAGQWRFADVLGLEEETLGSVPSPACALLLLFPLTAQHEN---- 61
           +E +P +  +++   G  G  +  ++  L++E+   +  P   L+ LF      E     
Sbjct: 14  IESDPGVFTELIKGFGCTGV-QVEEIWSLDKESF-ELLKPVHGLIFLFKWVPDKEPDGSV 187

Query: 62  FRKKQIEELKGQEVSPKVYFMKQTIGNSCGTIGLIHAVANNQDKLEFEDGSVLKQFLSET 121
            +  ++E         K++F KQ I N+C T  ++ ++  N    +   G  L  F    
Sbjct: 188 VQDSRLE---------KIFFAKQVINNACATQAIL-SILLNCSHADISLGDTLSSFKEFA 337

Query: 122 EKLSPEDRAKCFEKNEAIQAAHDSVAQEGQCRVDDKVN------FHFILFNNVDGHLYEL 175
           ++  P  R      ++ I+  H+S +++     D+K+       FHF+ +   DG LYEL
Sbjct: 338 QQFDPALRGLSLSNSDLIREVHNSFSRQQMFEFDEKMAKKDDDVFHFVGYIPFDGRLYEL 517

Query: 176 DGRMPFPVNHGASSEDSLLQDAAK--VCREFTEREQGEVRFSAVALC 220
           DG    PV+ GA   ++   D  +  + +   +    E+ F+ +A+ 
Sbjct: 518 DGLKDGPVDLGAIPTETEWTDVVRPVIEKRMQKYSADEIHFNLMAVV 658
>30672
          Length = 877

 Score = 29.3 bits (64), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 12/36 (33%), Positives = 20/36 (55%)
 Frame = -2

Query: 172 LYELDGRMPFPVNHGASSEDSLLQDAAKVCREFTER 207
           L+      P PV+H +    S+L  ++ +CR+ TER
Sbjct: 327 LFVTAASFPIPVHHLSXYPPSVLSSSSFLCRQKTER 220
>24758
          Length = 2094

 Score = 27.3 bits (59), Expect = 5.0,   Method: Compositional matrix adjust.
 Identities = 15/48 (31%), Positives = 22/48 (45%), Gaps = 1/48 (2%)
 Frame = +3

Query: 45  PACALLLLFPLTAQHENFRKKQIEELKGQEVSPKVY-FMKQTIGNSCG 91
           PAC L+  FP        RK    +L  Q  +P+ + F  Q++  SC 
Sbjct: 357 PACCLIAFFPQLGSETLCRK----QLTQQNATPRSFGFFSQSLSTSCS 488
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|47894398|ref|NP_001001491.1| tropomyosin 4 [Mus
musculus]
         (248 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

04603                                                                 113   7e-26
19700                                                                 111   2e-25
29815                                                                  35   0.025
05976                                                                  28   3.2  
27134                                                                  27   7.2  
>04603
          Length = 1101

 Score =  113 bits (283), Expect = 7e-26,   Method: Compositional matrix adjust.
 Identities = 76/215 (35%), Positives = 121/215 (56%)
 Frame = -2

Query: 31  LQRELDGERERREKAEGDAAALNRRIQLLEEELDRAQEQLATALQNLEEAEKAADESERG 90
           L+R++D ++    K E +   LNRRI LLEE+L+R++E+L TA + LEEA KAADESER 
Sbjct: 824 LKRDVDDKKSEIAKLESEMQGLNRRITLLEEDLERSEERLQTATEKLEEATKAADESERV 645

Query: 91  MKVIENRAMKDEEKMEILEMQLKEAKHITDEADRKYEEVARKLVILEGELKRAEERAEVS 150
            + +EN+    +E++E  E  L+ AK    E + +Y+E ARKLV +E +L+R EERAEV+
Sbjct: 644 RRTVENKLFAGDERLEECETDLRAAKQAAQEWEARYDESARKLVAMESDLERCEERAEVA 465

Query: 151 ELKCGDLEEELKNVTNNLXXXXXXXXXXXXXXXXXXXXXXXXSDKLKXXXXXXXXXXXXV 210
           E +  DLE++   +TN+L                        + +LK            V
Sbjct: 464 ERRVRDLEDQSHTLTNSLRSLELCEEKASQREDSYEETIRDLTQRLKDHESRAEVSEREV 285

Query: 211 SKLEKTIDDLEEKLAQAKEENVGLHQTLDQTLNEL 245
            +L+K ++ ++E L + +  N  L + +DQ + +L
Sbjct: 284 KRLQKLLEQMDEDLEEQRRANNCLQEEMDQCIGDL 180
>19700
          Length = 608

 Score =  111 bits (278), Expect = 2e-25,   Method: Compositional matrix adjust.
 Identities = 68/139 (48%), Positives = 96/139 (69%)
 Frame = -1

Query: 30  GLQRELDGERERREKAEGDAAALNRRIQLLEEELDRAQEQLATALQNLEEAEKAADESER 89
            L+RE +   E  ++ E D A LNRRIQLLEE+L+R++E+L TA + LEEA KAADESER
Sbjct: 443 SLKREKNKWSEEVQRLESDLAGLNRRIQLLEEDLERSEERLQTATEKLEEASKAADESER 264

Query: 90  GMKVIENRAMKDEEKMEILEMQLKEAKHITDEADRKYEEVARKLVILEGELKRAEERAEV 149
           G +  E +    EE++E +E +L+ AK    E + +YEEVAR+L +++ +L +AE RA+ 
Sbjct: 263 GRRTAEKKMFTGEERLEDVETELRTAKQAAREWESRYEEVARRLQVMDHDLGKAEYRADN 84

Query: 150 SELKCGDLEEELKNVTNNL 168
           SE K  +LEEE   +TNNL
Sbjct: 83  SERKARELEEESLTLTNNL 27
>29815
          Length = 337

 Score = 35.0 bits (79), Expect = 0.025,   Method: Compositional matrix adjust.
 Identities = 30/101 (29%), Positives = 45/101 (44%)
 Frame = +2

Query: 139 ELKRAEERAEVSELKCGDLEEELKNVTNNLXXXXXXXXXXXXXXXXXXXXXXXXSDKLKX 198
           +L+RAE R E +E KC +L+E+L  V NN+                        + +LK 
Sbjct: 2   DLERAETRLEAAESKCYELDEQLHVVGNNIKTLSIQNDQASQREDSYEETIRDLTQRLKD 181

Query: 199 XXXXXXXXXXXVSKLEKTIDDLEEKLAQAKEENVGLHQTLD 239
                      VSKL+K +D LE++L   KE+   +   LD
Sbjct: 182 CENRAQEAERTVSKLQKEVDRLEDELLVEKEKLKNISDELD 304
>05976
          Length = 1631

 Score = 28.1 bits (61), Expect = 3.2,   Method: Compositional matrix adjust.
 Identities = 13/20 (65%), Positives = 18/20 (90%)
 Frame = +3

Query: 51 ALNRRIQLLEEELDRAQEQL 70
           LNRRI LLEE+L+R++E+L
Sbjct: 3  GLNRRITLLEEDLERSEERL 62
>27134
          Length = 400

 Score = 26.9 bits (58), Expect = 7.2,   Method: Compositional matrix adjust.
 Identities = 12/28 (42%), Positives = 18/28 (64%)
 Frame = -2

Query: 115 AKHITDEADRKYEEVARKLVILEGELKR 142
           AKHIT   +RKY +  RK ++ + +L R
Sbjct: 105 AKHITKTKERKYTQNKRK*ILTQTKLTR 22
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|58037201|ref|NP_081630.1| WD repeat domain 51A [Mus
musculus]
         (405 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

30256                                                                 114   7e-26
02147                                                                 102   2e-22
19949                                                                  99   3e-21
00561                                                                  95   6e-20
13335                                                                  94   1e-19
17598                                                                  86   2e-17
12806                                                                  84   1e-16
02090                                                                  84   1e-16
27465                                                                  82   3e-16
01327                                                                  82   6e-16
12960                                                                  81   9e-16
12574                                                                  80   1e-15
17602                                                                  71   7e-13
03387                                                                  68   6e-12
00825                                                                  66   3e-11
03156                                                                  65   5e-11
19498                                                                  64   8e-11
15251                                                                  64   1e-10
35607                                                                  62   3e-10
17266                                                                  62   3e-10
13278                                                                  62   6e-10
03395                                                                  61   8e-10
26939                                                                  60   1e-09
24785                                                                  60   1e-09
01805                                                                  60   2e-09
31474                                                                  58   5e-09
02960                                                                  58   7e-09
15118                                                                  57   1e-08
14555                                                                  42   3e-08
01598                                                                  55   5e-08
16105                                                                  54   1e-07
21105                                                                  53   2e-07
01768                                                                  52   5e-07
18981                                                                  51   7e-07
11493                                                                  50   2e-06
01249                                                                  49   3e-06
16199                                                                  49   3e-06
31384                                                                  49   4e-06
15780                                                                  48   6e-06
15337                                                                  48   8e-06
37180                                                                  47   1e-05
30295                                                                  47   1e-05
31864                                                                  47   2e-05
10162                                                                  47   2e-05
21921                                                                  46   2e-05
21960                                                                  45   5e-05
27681                                                                  37   6e-05
19863                                                                  44   9e-05
17298                                                                  44   1e-04
19140                                                                  43   2e-04
39204                                                                  43   3e-04
04088                                                                  42   3e-04
27806                                                                  41   7e-04
03044                                                                  41   9e-04
02948                                                                  40   0.001
26107                                                                  40   0.001
29912                                                                  40   0.001
01462                                                                  40   0.002
38177                                                                  40   0.002
14500                                                                  39   0.003
15972                                                                  39   0.004
05393                                                                  39   0.005
30176                                                                  37   0.012
31118                                                                  36   0.036
06576                                                                  35   0.037
34005                                                                  35   0.063
10264                                                                  35   0.072
07665                                                                  35   0.072
20662                                                                  35   0.079
36111                                                                  34   0.091
11915                                                                  34   0.12 
27270                                                                  33   0.14 
13509                                                                  33   0.20 
31054                                                                  33   0.22 
30297                                                                  33   0.26 
04358                                                                  33   0.30 
04395                                                                  32   0.46 
07542                                                                  32   0.51 
20271                                                                  32   0.52 
27475                                                                  32   0.65 
35695                                                                  31   0.69 
34511                                                                  31   0.75 
25880                                                                  31   0.84 
20615                                                                  31   1.2  
07781                                                                  30   1.2  
04524                                                                  30   1.3  
07151                                                                  30   2.2  
30108                                                                  29   2.7  
18320                                                                  29   4.0  
27525                                                                  29   4.2  
38362                                                                  28   7.5  
30679                                                                  28   7.9  
37142                                                                  28   8.1  
03177                                                                  28   9.7  
>30256
          Length = 961

 Score =  114 bits (285), Expect = 7e-26,   Method: Compositional matrix adjust.
 Identities = 80/258 (31%), Positives = 124/258 (48%), Gaps = 3/258 (1%)
 Frame = +3

Query: 13  RHFKGHRDAVTCVDFSLNTKHLASGSMDSTLMIWHMKSQSRAYRFTGHKDAVTCVNFSPS 72
           ++  GH   V     + NT  + SGS D +L +W+  +    +   GH   V C   S S
Sbjct: 24  KNLIGHTGGVWSSQMTGNT--VISGSTDRSLKVWNADTGVCTHTLYGHSSTVRC--LSLS 191

Query: 73  GHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSLVTASDDKTVKVWST 132
           G  + SGSRD T+R+W         V   H A VR V +  DG+ +V+ + D TV+VW  
Sbjct: 192 GKKVVSGSRDATLRVWDIESGHCLNVLLGHMAAVRCVQY--DGKRVVSGAXDYTVRVWDP 365

Query: 133 HRQRFLFSLTQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKTSRECIHSYCEHGGFVTY 192
                L +L  H N V   +F  DG  +VS S D ++++WD    + +H+   H    + 
Sbjct: 366 DTASCLHTLQGHTNRVYSLQF--DGVYVVSGSLDTSIRVWDVRCGKLVHTLMGHQSLTSG 539

Query: 193 VDFHPSGTCIAAAGMDNTVKVWDARTHRLLQHY---QLHSAAVNALSFHPSGNYLITASS 249
           ++   +   + +   D+TVKVWD  T + LQ       H +AV  L F+    +++T S 
Sbjct: 540 LELKDN--LLVSGNADSTVKVWDVHTGKCLQTLLGPNKHRSAVTCLQFNKK--FVVTCSD 707

Query: 250 DSTLKILDLMEGRLLYTL 267
           D T+K+ DL  G  +  L
Sbjct: 708 DGTVKLWDLNTGDFIRNL 761

 Score = 93.2 bits (230), Expect = 2e-19,   Method: Compositional matrix adjust.
 Identities = 62/198 (31%), Positives = 99/198 (50%)
 Frame = +3

Query: 101 AHTATVRSVHFCSDGQSLVTASDDKTVKVWSTHRQRFLFSLTQHINWVRCAKFSPDGRLI 160
            HT  V S      G ++++ S D+++KVW+        +L  H + VRC   S  G+ +
Sbjct: 36  GHTGGVWSSQM--TGNTVISGSTDRSLKVWNADTGVCTHTLYGHSSTVRCLSLS--GKKV 203

Query: 161 VSASDDKTVKLWDKTSRECIHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDARTHR 220
           VS S D T+++WD  S  C++    H   V  V +   G  + +   D TV+VWD  T  
Sbjct: 204 VSGSRDATLRVWDIESGHCLNVLLGHMAAVRCVQY--DGKRVVSGAXDYTVRVWDPDTAS 377

Query: 221 LLQHYQLHSAAVNALSFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFS 280
            L   Q H+  V +L F   G Y+++ S D+++++ D+  G+L++TL GHQ  + T    
Sbjct: 378 CLHTLQGHTNRVYSLQF--DGVYVVSGSLDTSIRVWDVRCGKLVHTLMGHQ--SLTSGLE 545

Query: 281 RTGEYFASGGSDEQVMVW 298
                  SG +D  V VW
Sbjct: 546 LKDNLLVSGNADSTVKVW 599

 Score = 40.4 bits (93), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 26/83 (31%), Positives = 43/83 (51%)
 Frame = +3

Query: 216 ARTHRLLQHYQLHSAAVNALSFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPAT 275
           A T R +++   H+  V   S   +GN +I+ S+D +LK+ +   G   +TL+GH   +T
Sbjct: 3   AVTGRCIKNLIGHTGGV--WSSQMTGNTVISGSTDRSLKVWNADTGVCTHTLYGH--SST 170

Query: 276 TVAFSRTGEYFASGGSDEQVMVW 298
               S +G+   SG  D  + VW
Sbjct: 171 VRCLSLSGKKVVSGSRDATLRVW 239
>02147
          Length = 1547

 Score =  102 bits (255), Expect = 2e-22,   Method: Compositional matrix adjust.
 Identities = 75/253 (29%), Positives = 120/253 (47%), Gaps = 9/253 (3%)
 Frame = +2

Query: 57  FTGHKDAVTCVNFSPSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQ 116
           F GHK AV     +      A+G+ D + +IW    KGE     +H   V+SV F  DG 
Sbjct: 161 FEGHKGAVWGATLNREATRAATGAADFSAKIWDAE-KGEELQTFSHKHIVKSVDFSHDGT 337

Query: 117 SLVTASDDKTVKVWS-THRQRFLFSLTQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKT 175
           +L+T S++K +KV+   +      S   H + ++ A F  DG+ I+SASDDKTV+LW   
Sbjct: 338 ALLTGSNEKLLKVFDLVNTDAEPKSFAGHTSNIKGALFLSDGKRIISASDDKTVRLWSLE 517

Query: 176 SRECIHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKV--------WDARTHRLLQHYQL 227
           +       C+    V  + F    T +  +   NT+ V        + A T R ++ ++ 
Sbjct: 518 T-------CQE---VQQLTFDTPPTSLTLSPDKNTIIVTHSQNIAFYQADTLREMKKFEA 667

Query: 228 HSAAVNALSFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGEYFA 287
             A +++ S H S  + +    D  +   D   G+ + +  GH GP   V FS  GE +A
Sbjct: 668 E-APISSASLHQSERFFVAGGEDFKMYKFDYETGKEIESFKGHFGPVHCVRFSPDGELYA 844

Query: 288 SGGSDEQVMVWKS 300
           SG  D  + +W++
Sbjct: 845 SGSEDGTLRLWQT 883

 Score = 85.9 bits (211), Expect = 3e-17,   Method: Compositional matrix adjust.
 Identities = 66/252 (26%), Positives = 107/252 (42%), Gaps = 45/252 (17%)
 Frame = +2

Query: 15  FKGHRDAVTCVDFSLNTKHLASGSMDSTLMIWHMKSQSRAYRFTGHKDAVTCVNFSPSGH 74
           F+GH+ AV     +      A+G+ D +  IW  +       F+ HK  V  V+FS  G 
Sbjct: 161 FEGHKGAVWGATLNREATRAATGAADFSAKIWDAEKGEELQTFS-HKHIVKSVDFSHDGT 337

Query: 75  LLASGSRDKTVRIW-VPNVKGESTVFRAHTATVRSVHFCSDGQSLVTASDDKTVKVWS-- 131
            L +GS +K ++++ + N   E   F  HT+ ++   F SDG+ +++ASDDKTV++WS  
Sbjct: 338 ALLTGSNEKLLKVFDLVNTDAEPKSFAGHTSNIKGALFLSDGKRIISASDDKTVRLWSLE 517

Query: 132 ----------------------------THRQRFLFSLTQHINWVRCAKFSPDG------ 157
                                       TH Q   F     +  ++  KF  +       
Sbjct: 518 TCQEVQQLTFDTPPTSLTLSPDKNTIIVTHSQNIAFYQADTLREMK--KFEAEAPISSAS 691

Query: 158 -----RLIVSASDDKTVKLWDKTSRECIHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVK 212
                R  V+  +D  +  +D  + + I S+  H G V  V F P G   A+   D T++
Sbjct: 692 LHQSERFFVAGGEDFKMYKFDYETGKEIESFKGHFGPVHCVRFSPDGELYASGSEDGTLR 871

Query: 213 VWD---ARTHRL 221
           +W     RT+ L
Sbjct: 872 LWQTTIGRTYGL 907
>19949
          Length = 903

 Score = 99.0 bits (245), Expect = 3e-21,   Method: Compositional matrix adjust.
 Identities = 59/177 (33%), Positives = 89/177 (50%)
 Frame = +2

Query: 106 VRSVHFCSDGQSLVTASDDKTVKVWSTHRQRFLFSLTQHINWVRCAKFSPDGRLIVSASD 165
           V+S+ F   G    + S D  VK+W   R+  +++   H   V C +FSPDGR I SAS+
Sbjct: 2   VKSLDFHPYGAYTASGSMDCNVKLWDIRRKGCIYTYKGHTGCVCCLRFSPDGRWIASASE 181

Query: 166 DKTVKLWDKTSRECIHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDARTHRLLQHY 225
           D  VKLWD T+ + +     H   V  ++FHP    +A+   D TVK WD  T +L+   
Sbjct: 182 DGLVKLWDLTAGKLLTDLKLHRDAVNTIEFHPHEFLLASGSADRTVKFWDLETFQLISTT 361

Query: 226 QLHSAAVNALSFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRT 282
           +  + ++ ++ FHP G  L + S D TLK+       L  T+    G    ++ S T
Sbjct: 362 EPEANSIRSILFHPDGVCLYSGSKD-TLKVYHWEPLELYDTVSVPWGQVCDMSISNT 529

 Score = 92.4 bits (228), Expect = 3e-19,   Method: Compositional matrix adjust.
 Identities = 53/145 (36%), Positives = 70/145 (48%)
 Frame = +2

Query: 148 VRCAKFSPDGRLIVSASDDKTVKLWDKTSRECIHSYCEHGGFVTYVDFHPSGTCIAAAGM 207
           V+   F P G    S S D  VKLWD   + CI++Y  H G V  + F P G  IA+A  
Sbjct: 2   VKSLDFHPYGAYTASGSMDCNVKLWDIRRKGCIYTYKGHTGCVCCLRFSPDGRWIASASE 181

Query: 208 DNTVKVWDARTHRLLQHYQLHSAAVNALSFHPSGNYLITASSDSTLKILDLMEGRLLYTL 267
           D  VK+WD    +LL   +LH  AVN + FHP    L + S+D T+K  DL   +L+ T 
Sbjct: 182 DGLVKLWDLTAGKLLTDLKLHRDAVNTIEFHPHEFLLASGSADRTVKFWDLETFQLISTT 361

Query: 268 HGHQGPATTVAFSRTGEYFASGGSD 292
                   ++ F   G    SG  D
Sbjct: 362 EPEANSIRSILFHPDGVCLYSGSKD 436

 Score = 87.8 bits (216), Expect = 6e-18,   Method: Compositional matrix adjust.
 Identities = 50/151 (33%), Positives = 77/151 (50%)
 Frame = +2

Query: 64  VTCVNFSPSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSLVTASD 123
           V  ++F P G   ASGS D  V++W    KG    ++ HT  V  + F  DG+ + +AS+
Sbjct: 2   VKSLDFHPYGAYTASGSMDCNVKLWDIRRKGCIYTYKGHTGCVCCLRFSPDGRWIASASE 181

Query: 124 DKTVKVWSTHRQRFLFSLTQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKTSRECIHSY 183
           D  VK+W     + L  L  H + V   +F P   L+ S S D+TVK WD  + + I + 
Sbjct: 182 DGLVKLWDLTAGKLLTDLKLHRDAVNTIEFHPHEFLLASGSADRTVKFWDLETFQLISTT 361

Query: 184 CEHGGFVTYVDFHPSGTCIAAAGMDNTVKVW 214
                 +  + FHP G C+  +G  +T+KV+
Sbjct: 362 EPEANSIRSILFHPDGVCL-YSGSKDTLKVY 451

 Score = 82.0 bits (201), Expect = 3e-16,   Method: Compositional matrix adjust.
 Identities = 47/151 (31%), Positives = 72/151 (47%)
 Frame = +2

Query: 22  VTCVDFSLNTKHLASGSMDSTLMIWHMKSQSRAYRFTGHKDAVTCVNFSPSGHLLASGSR 81
           V  +DF     + ASGSMD  + +W ++ +   Y + GH   V C+ FSP G  +AS S 
Sbjct: 2   VKSLDFHPYGAYTASGSMDCNVKLWDIRRKGCIYTYKGHTGCVCCLRFSPDGRWIASASE 181

Query: 82  DKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSLVTASDDKTVKVWSTHRQRFLFSL 141
           D  V++W        T  + H   V ++ F      L + S D+TVK W     + + + 
Sbjct: 182 DGLVKLWDLTAGKLLTDLKLHRDAVNTIEFHPHEFLLASGSADRTVKFWDLETFQLISTT 361

Query: 142 TQHINWVRCAKFSPDGRLIVSASDDKTVKLW 172
               N +R   F PDG  + S S D T+K++
Sbjct: 362 EPEANSIRSILFHPDGVCLYSGSKD-TLKVY 451

 Score = 79.3 bits (194), Expect = 2e-15,   Method: Compositional matrix adjust.
 Identities = 40/109 (36%), Positives = 55/109 (50%)
 Frame = +2

Query: 190 VTYVDFHPSGTCIAAAGMDNTVKVWDARTHRLLQHYQLHSAAVNALSFHPSGNYLITASS 249
           V  +DFHP G   A+  MD  VK+WD R    +  Y+ H+  V  L F P G ++ +AS 
Sbjct: 2   VKSLDFHPYGAYTASGSMDCNVKLWDIRRKGCIYTYKGHTGCVCCLRFSPDGRWIASASE 181

Query: 250 DSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGEYFASGGSDEQVMVW 298
           D  +K+ DL  G+LL  L  H+    T+ F       ASG +D  V  W
Sbjct: 182 DGLVKLWDLTAGKLLTDLKLHRDAVNTIEFHPHEFLLASGSADRTVKFW 328

 Score = 70.1 bits (170), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 47/154 (30%), Positives = 72/154 (46%)
 Frame = +2

Query: 15  FKGHRDAVTCVDFSLNTKHLASGSMDSTLMIWHMKSQSRAYRFTGHKDAVTCVNFSPSGH 74
           +KGH   V C+ FS + + +AS S D  + +W + +         H+DAV  + F P   
Sbjct: 107 YKGHTGCVCCLRFSPDGRWIASASEDGLVKLWDLTAGKLLTDLKLHRDAVNTIEFHPHEF 286

Query: 75  LLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSLVTASDDKTVKVWSTHR 134
           LLASGS D+TV+ W        +       ++RS+ F  DG  L + S D T+KV+  H 
Sbjct: 287 LLASGSADRTVKFWDLETFQLISTTEPEANSIRSILFHPDGVCLYSGSKD-TLKVY--HW 457

Query: 135 QRFLFSLTQHINWVRCAKFSPDGRLIVSASDDKT 168
           +      T  + W +    S     ++ AS  KT
Sbjct: 458 EPLELYDTVSVPWGQVCDMSISNTQLIGASFYKT 559
>00561
          Length = 1003

 Score = 94.7 bits (234), Expect = 6e-20,   Method: Compositional matrix adjust.
 Identities = 70/233 (30%), Positives = 105/233 (45%), Gaps = 10/233 (4%)
 Frame = -3

Query: 76  LASGSRDKTVRIWV------PNVKGESTVFRAHTATVRSVHFCSDGQSLVTASDDKTVKV 129
           + S SRDKT+ +W        N          H+  +  V   SDG   ++ S D+T+++
Sbjct: 965 IISASRDKTLIVWKLTRDEDTNYGYPQKRLYGHSHFISDVVLSSDGNYALSGSWDQTLRL 786

Query: 130 WSTHRQRFLFSLTQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKTSRECIHSYCE--HG 187
           W     +       H   V    FS D R IVS S DKT+KLW+ T  EC  +  E  H 
Sbjct: 785 WDLAAGKTTRRFEGHTKDVLSVAFSADNRQIVSGSRDKTIKLWN-TLAECKFTIQEDGHT 609

Query: 188 GFVTYVDFHP--SGTCIAAAGMDNTVKVWDARTHRLLQHYQLHSAAVNALSFHPSGNYLI 245
            +V+ V F P  S   I + G D TVKVW+    +L  ++  H+  +N ++  P G+   
Sbjct: 608 DWVSCVRFSPNHSNPIIVSCGWDRTVKVWNLANCKLKNNHHGHNGYLNTVTVSPDGSLCT 429

Query: 246 TASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGEYFASGGSDEQVMVW 298
           +   DS   + DL +G+ LYTL  H      + FS    Y+        + +W
Sbjct: 428 SGGKDSKALLWDLNDGKNLYTLE-HNDIINALCFS-PNRYWLCVAYGPSIKIW 276

 Score = 87.4 bits (215), Expect = 9e-18,   Method: Compositional matrix adjust.
 Identities = 59/207 (28%), Positives = 96/207 (46%), Gaps = 3/207 (1%)
 Frame = -3

Query: 12  ERHFKGHRDAVTCVDFSLNTKHLASGSMDSTLMIWHMKSQSRAYRFTGHKDAVTCVNFSP 71
           ++   GH   ++ V  S +  +  SGS D TL +W + +     RF GH   V  V FS 
Sbjct: 887 QKRLYGHSHFISDVVLSSDGNYALSGSWDQTLRLWDLAAGKTTRRFEGHTKDVLSVAFSA 708

Query: 72  SGHLLASGSRDKTVRIWVPNVKGESTVFR-AHTATVRSVHFCSDGQS--LVTASDDKTVK 128
               + SGSRDKT+++W    + + T+    HT  V  V F  +  +  +V+   D+TVK
Sbjct: 707 DNRQIVSGSRDKTIKLWNTLAECKFTIQEDGHTDWVSCVRFSPNHSNPIIVSCGWDRTVK 528

Query: 129 VWSTHRQRFLFSLTQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKTSRECIHSYCEHGG 188
           VW+    +   +   H  ++     SPDG L  S   D    LWD    + +++  EH  
Sbjct: 527 VWNLANCKLKNNHHGHNGYLNTVTVSPDGSLCTSGGKDSKALLWDLNDGKNLYTL-EHND 351

Query: 189 FVTYVDFHPSGTCIAAAGMDNTVKVWD 215
            +  + F P+   +  A    ++K+WD
Sbjct: 350 IINALCFSPNRYWLCVA-YGPSIKIWD 273

 Score = 76.3 bits (186), Expect = 2e-14,   Method: Compositional matrix adjust.
 Identities = 55/200 (27%), Positives = 90/200 (45%), Gaps = 12/200 (6%)
 Frame = -3

Query: 114 DGQSLVTASDDKTVKVWSTHR---------QRFLFSLTQHINWVRCAKFSPDGRLIVSAS 164
           D  ++++AS DKT+ VW   R         Q+ L+    H +++     S DG   +S S
Sbjct: 977 DPDTIISASRDKTLIVWKLTRDEDTNYGYPQKRLYG---HSHFISDVVLSSDGNYALSGS 807

Query: 165 DDKTVKLWDKTSRECIHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDARTH-RLLQ 223
            D+T++LWD  + +    +  H   V  V F      I +   D T+K+W+     +   
Sbjct: 806 WDQTLRLWDLAAGKTTRRFEGHTKDVLSVAFSADNRQIVSGSRDKTIKLWNTLAECKFTI 627

Query: 224 HYQLHSAAVNALSFHP--SGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSR 281
               H+  V+ + F P  S   +++   D T+K+ +L   +L    HGH G   TV  S 
Sbjct: 626 QEDGHTDWVSCVRFSPNHSNPIIVSCGWDRTVKVWNLANCKLKNNHHGHNGYLNTVTVSP 447

Query: 282 TGEYFASGGSDEQVMVWKSN 301
            G    SGG D + ++W  N
Sbjct: 446 DGSLCTSGGKDSKALLWDLN 387

 Score = 32.7 bits (73), Expect(2) = 0.001,   Method: Compositional matrix adjust.
 Identities = 19/78 (24%), Positives = 34/78 (43%)
 Frame = -3

Query: 11  LERHFKGHRDAVTCVDFSLNTKHLASGSMDSTLMIWHMKSQSRAYRFTGHKDAVTCVNFS 70
           L+ +  GH   +  V  S +     SG  DS  ++W +      Y    H D +  + FS
Sbjct: 503 LKNNHHGHNGYLNTVTVSPDGSLCTSGGKDSKALLWDLNDGKNLYTLE-HNDIINALCFS 327

Query: 71  PSGHLLASGSRDKTVRIW 88
           P+ + L   +   +++IW
Sbjct: 326 PNRYWLCV-AYGPSIKIW 276

 Score = 26.9 bits (58), Expect(2) = 0.001,   Method: Compositional matrix adjust.
 Identities = 11/35 (31%), Positives = 18/35 (51%)
 Frame = -2

Query: 96  STVFRAHTATVRSVHFCSDGQSLVTASDDKTVKVW 130
           S   +A      S+ + +DGQ+L     D T++VW
Sbjct: 228 SPTSKAEQPQCLSLAWSTDGQTLFAGYSDNTIRVW 124
>13335
          Length = 863

 Score = 93.6 bits (231), Expect = 1e-19,   Method: Compositional matrix adjust.
 Identities = 64/220 (29%), Positives = 101/220 (45%), Gaps = 24/220 (10%)
 Frame = +1

Query: 19  RDAVTCVDFSLNTKHLASGSMDSTLMIWHMKSQSRAYRFTGHKDAVTCVNFSPSGHLLAS 78
           + ++    FS ++ HL SGS D T+ +W + +Q     + GH+D+V  + +SP+GH L S
Sbjct: 61  KSSIRVCKFSPSSSHLVSGSDDDTICMWEVATQKLVRSYVGHEDSVMALAYSPNGHYLVS 240

Query: 79  GSRDKTVRIW---VPNVKGESTVFRAHTATVRSVHF-------CSDGQS-----LVTASD 123
           GS +  + +W     + +  +    AH   V    F       C++  S     L T   
Sbjct: 241 GSPNGDLYVWDASFGHCRHLTLRVDAHDLGVTCCEFSPTFGTACAENSSTCNLLLATGGK 420

Query: 124 DKTVKVWSTHRQ--------RFLFSLTQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKT 175
           D  +K+W+   Q        +    L+ H + V    FSP   L+ S S DK+V+LWD  
Sbjct: 421 DNLIKLWTFSAQVGSPEVTLQCRDILSGHSDLVMACAFSPSSALLASGSFDKSVRLWDSV 600

Query: 176 SRECIHSY-CEHGGFVTYVDFHPSGTCIAAAGMDNTVKVW 214
               + S    H  FVT   F   GT +A+  MD  +K+W
Sbjct: 601 KGVALFSIEACHSRFVTCCAFSIDGTLLASGSMDRIIKIW 720

 Score = 86.7 bits (213), Expect = 1e-17,   Method: Compositional matrix adjust.
 Identities = 68/233 (29%), Positives = 104/233 (44%), Gaps = 24/233 (10%)
 Frame = +1

Query: 91  NVKGESTVFRAHTATVRSVHFCSDGQSLVTASDDKTVKVWSTHRQRFLFSLTQHINWVRC 150
           ++KGE     A  +++R   F      LV+ SDD T+ +W    Q+ + S   H + V  
Sbjct: 31  SIKGEYQ--HASKSSIRVCKFSPSSSHLVSGSDDDTICMWEVATQKLVRSYVGHEDSVMA 204

Query: 151 AKFSPDGRLIVSASDDKTVKLWDKTSRECIHSYCE---HGGFVTYVDFHP---------S 198
             +SP+G  +VS S +  + +WD +   C H       H   VT  +F P         S
Sbjct: 205 LAYSPNGHYLVSGSPNGDLYVWDASFGHCRHLTLRVDAHDLGVTCCEFSPTFGTACAENS 384

Query: 199 GTC---IAAAGMDNTVKVWD-----ARTHRLLQHYQL---HSAAVNALSFHPSGNYLITA 247
            TC   +A  G DN +K+W            LQ   +   HS  V A +F PS   L + 
Sbjct: 385 STCNLLLATGGKDNLIKLWTFSAQVGSPEVTLQCRDILSGHSDLVMACAFSPSSALLASG 564

Query: 248 SSDSTLKILDLMEGRLLYTLHG-HQGPATTVAFSRTGEYFASGGSDEQVMVWK 299
           S D ++++ D ++G  L+++   H    T  AFS  G   ASG  D  + +WK
Sbjct: 565 SFDKSVRLWDSVKGVALFSIEACHSRFVTCCAFSIDGTLLASGSMDRIIKIWK 723

 Score = 82.8 bits (203), Expect = 2e-16,   Method: Compositional matrix adjust.
 Identities = 56/189 (29%), Positives = 86/189 (45%), Gaps = 24/189 (12%)
 Frame = +1

Query: 11  LERHFKGHRDAVTCVDFSLNTKHLASGSMDSTLMIWHMK---SQSRAYRFTGHKDAVTCV 67
           L R + GH D+V  + +S N  +L SGS +  L +W       +    R   H   VTC 
Sbjct: 163 LVRSYVGHEDSVMALAYSPNGHYLVSGSPNGDLYVWDASFGHCRHLTLRVDAHDLGVTCC 342

Query: 68  NFSPS------------GHLLASGSRDKTVRIWV-------PNVKGES-TVFRAHTATVR 107
            FSP+              LLA+G +D  +++W        P V  +   +   H+  V 
Sbjct: 343 EFSPTFGTACAENSSTCNLLLATGGKDNLIKLWTFSAQVGSPEVTLQCRDILSGHSDLVM 522

Query: 108 SVHFCSDGQSLVTASDDKTVKVWSTHRQRFLFSLTQ-HINWVRCAKFSPDGRLIVSASDD 166
           +  F      L + S DK+V++W + +   LFS+   H  +V C  FS DG L+ S S D
Sbjct: 523 ACAFSPSSALLASGSFDKSVRLWDSVKGVALFSIEACHSRFVTCCAFSIDGTLLASGSMD 702

Query: 167 KTVKLWDKT 175
           + +K+W  T
Sbjct: 703 RIIKIWKLT 729

 Score = 58.5 bits (140), Expect = 5e-09,   Method: Compositional matrix adjust.
 Identities = 47/177 (26%), Positives = 71/177 (40%), Gaps = 24/177 (13%)
 Frame = +1

Query: 148 VRCAKFSPDGRLIVSASDDKTVKLWDKTSRECIHSYCEHGGFVTYVDFHPSGTCIAAAGM 207
           +R  KFSP    +VS SDD T+ +W+  +++ + SY  H   V  + + P+G  + +   
Sbjct: 70  IRVCKFSPSSSHLVSGSDDDTICMWEVATQKLVRSYVGHEDSVMALAYSPNGHYLVSGSP 249

Query: 208 DNTVKVWDA---RTHRLLQHYQLHSAAVNALSFHPSGNYLITASSDSTLKILDLMEGR-- 262
           +  + VWDA       L      H   V    F P+      A + ST  +L    G+  
Sbjct: 250 NGDLYVWDASFGHCRHLTLRVDAHDLGVTCCEFSPTFG-TACAENSSTCNLLLATGGKDN 426

Query: 263 --LLYT-----------------LHGHQGPATTVAFSRTGEYFASGGSDEQVMVWKS 300
              L+T                 L GH       AFS +    ASG  D+ V +W S
Sbjct: 427 LIKLWTFSAQVGSPEVTLQCRDILSGHSDLVMACAFSPSSALLASGSFDKSVRLWDS 597

 Score = 55.1 bits (131), Expect = 4e-08,   Method: Compositional matrix adjust.
 Identities = 27/93 (29%), Positives = 50/93 (53%), Gaps = 1/93 (1%)
 Frame = +1

Query: 211 VKVWDARTHRLLQHYQLHS-AAVNALSFHPSGNYLITASSDSTLKILDLMEGRLLYTLHG 269
           V VWD +T  +   YQ  S +++    F PS ++L++ S D T+ + ++   +L+ +  G
Sbjct: 4   VIVWDVKTGSIKGEYQHASKSSIRVCKFSPSSSHLVSGSDDDTICMWEVATQKLVRSYVG 183

Query: 270 HQGPATTVAFSRTGEYFASGGSDEQVMVWKSNF 302
           H+     +A+S  G Y  SG  +  + VW ++F
Sbjct: 184 HEDSVMALAYSPNGHYLVSGSPNGDLYVWDASF 282

 Score = 33.5 bits (75), Expect = 0.16,   Method: Compositional matrix adjust.
 Identities = 16/35 (45%), Positives = 20/35 (57%)
 Frame = +1

Query: 18  HRDAVTCVDFSLNTKHLASGSMDSTLMIWHMKSQS 52
           H   VTC  FS++   LASGSMD  + IW +   S
Sbjct: 634 HSRFVTCCAFSIDGTLLASGSMDRIIKIWKLTDTS 738
>17598
          Length = 875

 Score = 85.9 bits (211), Expect = 2e-17,   Method: Compositional matrix adjust.
 Identities = 64/239 (26%), Positives = 101/239 (42%), Gaps = 14/239 (5%)
 Frame = +1

Query: 74  HLLASGSRDKTVRIW--VPNVKGEST--------VFRAHTATVRSVHFCSDGQSLVTASD 123
             L  G RDK + +W  VP   G+            + H+  V  V   +D + ++++S 
Sbjct: 4   EFLIXGGRDKLLIVWDLVPRKDGDEDETWGGPRRTLQGHSHFVSDVSLSADSRYVLSSSW 183

Query: 124 DKTVKVWSTHRQRFLFSLTQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKTSRECIHSY 183
           D T+++W   +         H        FSPD R I S   DK +K+W+ T  EC  + 
Sbjct: 184 DATLRLWDIKKGNTTRRFISHTRDALAVAFSPDNRQIASGGRDKALKIWN-TVGECKFTV 360

Query: 184 --CEHGGFVTYVDFHPSGT--CIAAAGMDNTVKVWDARTHRLLQHYQLHSAAVNALSFHP 239
               H  +VT V FH       + +A MD T+KVWD +T  L   +  H   +NA+    
Sbjct: 361 DANSHQDWVTCVKFHQDAKSPLVVSASMDKTIKVWDNQTMTLKHTFVGHKTQINAIDLAL 540

Query: 240 SGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGEYFASGGSDEQVMVW 298
              YL + S D  +   ++  G  L  +         V FS   +Y+   G+ E + +W
Sbjct: 541 KTYYLASGSKDGIVMTWNIQNGTFLGKIDC-DCEVNAVKFS-PNKYWLFVGTSEGIQIW 711

 Score = 83.2 bits (204), Expect = 2e-16,   Method: Compositional matrix adjust.
 Identities = 73/256 (28%), Positives = 108/256 (42%), Gaps = 19/256 (7%)
 Frame = +1

Query: 13  RHFKGHRDAVTCVDFSLNTKHLASGSMDSTLMIWHMKSQSRAYRFTGHKDAVTCVNFSPS 72
           R  +GH   V+ V  S +++++ S S D+TL +W +K  +   RF  H      V FSP 
Sbjct: 103 RTLQGHSHFVSDVSLSADSRYVLSSSWDATLRLWDIKKGNTTRRFISHTRDALAVAFSPD 282

Query: 73  GHLLASGSRDKTVRIWVPNVKGESTV---FRAHTATVRSVHFCSDGQS--LVTASDDKTV 127
              +ASG RDK ++IW  N  GE        +H   V  V F  D +S  +V+AS DKT+
Sbjct: 283 NRQIASGGRDKALKIW--NTVGECKFTVDANSHQDWVTCVKFHQDAKSPLVVSASMDKTI 456

Query: 128 KVWSTHRQRFLFSLTQHINWVRCAKFSPDGRLIVSASDDKTVKLW---DKTSRECIHSYC 184
           KVW         +   H   +     +     + S S D  V  W   + T    I   C
Sbjct: 457 KVWDNQTMTLKHTFVGHKTQINAIDLALKTYYLASGSKDGIVMTWNIQNGTFLGKIDCDC 636

Query: 185 EHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDARTHRLL----------QHY-QLHSAAVN 233
           E    V  V F P+   +   G    +++WD    + +          QH  Q  S A  
Sbjct: 637 E----VNAVKFSPNKYWL-FVGTSEGIQIWDLPNQKKIKDIRASPIDAQHKSQKKSIACT 801

Query: 234 ALSFHPSGNYLITASS 249
           +L++  SG+ L    S
Sbjct: 802 SLAWDASGHTLFAGFS 849

 Score = 50.4 bits (119), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 30/88 (34%), Positives = 50/88 (56%), Gaps = 4/88 (4%)
 Frame = +1

Query: 10  SLERHFKGHRDAVTCVDFSLNTKHLASGSMDSTLMIWHMKSQSRAYRFTGHKDA---VTC 66
           +L+  F GH+  +  +D +L T +LASGS D  +M W++++ +    F G  D    V  
Sbjct: 481 TLKHTFVGHKTQINAIDLALKTYYLASGSKDGIVMTWNIQNGT----FLGKIDCDCEVNA 648

Query: 67  VNFSPSGHLLASGSRDKTVRIW-VPNVK 93
           V FSP+ + L  G+ +  ++IW +PN K
Sbjct: 649 VKFSPNKYWLFVGTSE-GIQIWDLPNQK 729

 Score = 47.0 bits (110), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 24/75 (32%), Positives = 39/75 (52%)
 Frame = +1

Query: 226 QLHSAAVNALSFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGEY 285
           Q HS  V+ +S      Y++++S D+TL++ D+ +G        H   A  VAFS     
Sbjct: 112 QGHSHFVSDVSLSADSRYVLSSSWDATLRLWDIKKGNTTRRFISHTRDALAVAFSPDNRQ 291

Query: 286 FASGGSDEQVMVWKS 300
            ASGG D+ + +W +
Sbjct: 292 IASGGRDKALKIWNT 336
>12806
          Length = 961

 Score = 84.0 bits (206), Expect = 1e-16,   Method: Compositional matrix adjust.
 Identities = 63/207 (30%), Positives = 91/207 (43%), Gaps = 5/207 (2%)
 Frame = +3

Query: 13  RHFKGHRDAVTCVDFSLNTKHLASGSMDSTLMIWHMKSQSRAYRFTGHKDAVTCVNFSPS 72
           +   GH   ++ +  S +++   S S D+TL +W +K  S   RF  H   V  V FSP 
Sbjct: 147 KTLTGHSHFISDLALSADSRFALSSSWDATLRLWDIKKGSTTSRFINHTRDVLTVAFSPD 326

Query: 73  GHLLASGSRDKTVRIWVPNVKGE---STVFRAHTATVRSVHFCSDGQS--LVTASDDKTV 127
              +ASG RDK ++IW  N+ GE   +    AHT  V  V F  D ++  +V+AS+DKT+
Sbjct: 327 NRQIASGGRDKNLKIW--NIMGECKYTVDANAHTDWVTCVRFHQDTKNPIVVSASNDKTI 500

Query: 128 KVWSTHRQRFLFSLTQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKTSRECIHSYCEHG 187
           KVW  H      +   H   +     S +   +VS S D     W+             G
Sbjct: 501 KVWDNHTMTLKNTFVGHKAQITALDMSTN--YLVSGSKDGIAMTWN----------VAEG 644

Query: 188 GFVTYVDFHPSGTCIAAAGMDNTVKVW 214
            FV  +D       I     +N  KVW
Sbjct: 645 SFVGKIDCDDQINAIKFNIENNKKKVW 725

 Score = 80.5 bits (197), Expect = 1e-15,   Method: Compositional matrix adjust.
 Identities = 52/222 (23%), Positives = 96/222 (43%), Gaps = 13/222 (5%)
 Frame = +3

Query: 34  LASGSMDSTLMIWHMKSQSRAYR----------FTGHKDAVTCVNFSPSGHLLASGSRDK 83
           L SG  D+ +++W +  +                TGH   ++ +  S       S S D 
Sbjct: 54  LISGGRDNNIIVWDL*PKKDGDEDQTWGVPRKTLTGHSHFISDLALSADSRFALSSSWDA 233

Query: 84  TVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSLVTASDDKTVKVWSTHRQ-RFLFSLT 142
           T+R+W       ++ F  HT  V +V F  D + + +   DK +K+W+   + ++     
Sbjct: 234 TLRLWDIKKGSTTSRFINHTRDVLTVAFSPDNRQIASGGRDKNLKIWNIMGECKYTVDAN 413

Query: 143 QHINWVRCAKFSPDGR--LIVSASDDKTVKLWDKTSRECIHSYCEHGGFVTYVDFHPSGT 200
            H +WV C +F  D +  ++VSAS+DKT+K+WD  +    +++  H   +T +D   S  
Sbjct: 414 AHTDWVTCVRFHQDTKNPIVVSASNDKTIKVWDNHTMTLKNTFVGHKAQITALDM--STN 587

Query: 201 CIAAAGMDNTVKVWDARTHRLLQHYQLHSAAVNALSFHPSGN 242
            + +   D     W+      +         +NA+ F+   N
Sbjct: 588 YLVSGSKDGIAMTWNVAEGSFVGKIDCDD-QINAIKFNIENN 710

 Score = 55.1 bits (131), Expect = 5e-08,   Method: Compositional matrix adjust.
 Identities = 40/171 (23%), Positives = 73/171 (42%), Gaps = 5/171 (2%)
 Frame = +3

Query: 15  FKGHRDAVTCVDFSLNTKHLASGSMDSTLMIWHMKSQSR-AYRFTGHKDAVTCVNF--SP 71
           F  H   V  V FS + + +ASG  D  L IW++  + +       H D VTCV F    
Sbjct: 279 FINHTRDVLTVAFSPDNRQIASGGRDKNLKIWNIMGECKYTVDANAHTDWVTCVRFHQDT 458

Query: 72  SGHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSLVTASDDKTVKVWS 131
              ++ S S DKT+++W  +       F  H A + ++   ++   LV+ S D     W+
Sbjct: 459 KNPIVVSASNDKTIKVWDNHTMTLKNTFVGHKAQITALDMSTN--YLVSGSKDGIAMTWN 632

Query: 132 THRQRFLFSL--TQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKTSRECI 180
                F+  +     IN ++    +   ++ +       +++WD +  + I
Sbjct: 633 VAEGSFVGKIDCDDQINAIKFNIENNKKKVWLFIGTQNGIQIWDYSGEKKI 785

 Score = 45.4 bits (106), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 28/107 (26%), Positives = 47/107 (43%), Gaps = 10/107 (9%)
 Frame = +3

Query: 202 IAAAGMDNTVKVWDARTHRLLQHYQL----------HSAAVNALSFHPSGNYLITASSDS 251
           + + G DN + VWD    +     Q           HS  ++ L+      + +++S D+
Sbjct: 54  LISGGRDNNIIVWDL*PKKDGDEDQTWGVPRKTLTGHSHFISDLALSADSRFALSSSWDA 233

Query: 252 TLKILDLMEGRLLYTLHGHQGPATTVAFSRTGEYFASGGSDEQVMVW 298
           TL++ D+ +G        H     TVAFS      ASGG D+ + +W
Sbjct: 234 TLRLWDIKKGSTTSRFINHTRDVLTVAFSPDNRQIASGGRDKNLKIW 374
>02090
          Length = 1841

 Score = 83.6 bits (205), Expect = 1e-16,   Method: Compositional matrix adjust.
 Identities = 48/179 (26%), Positives = 85/179 (47%), Gaps = 2/179 (1%)
 Frame = -3

Query: 126  TVKVW--STHRQRFLFSLTQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKTSRECIHSY 183
            T+ +W  +T   R    LT           SPDG++  S   D  + +WD  ++  +  +
Sbjct: 1689 TLSIWDLATPTPRIKAELTSSAPACYALAISPDGKVCFSCCSDGNIAVWDLHNQTLVRQF 1510

Query: 184  CEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDARTHRLLQHYQLHSAAVNALSFHPSGNY 243
              H    + +D  P GT +   G+DNTV+ WD R  R LQ +   S+ + +L + P+G +
Sbjct: 1509 QGHTDGASCIDISPDGTKLWTGGLDNTVRSWDLREGRQLQQHDF-SSQIFSLGYCPTGEW 1333

Query: 244  LITASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGEYFASGGSDEQVMVWKSNF 302
            L      S +++L   +    Y LH H+    ++ F+  G++F S G D  +  W++ +
Sbjct: 1332 LAVGMESSNVEVLHHSKPD-KYQLHLHESCVLSLKFAYCGKWFVSTGKDNLLNAWRTPY 1159

 Score = 60.8 bits (146), Expect = 9e-10,   Method: Compositional matrix adjust.
 Identities = 43/172 (25%), Positives = 74/172 (43%)
 Frame = -3

Query: 1    MAAPSQEDPSLERHFKGHRDAVTCVDFSLNTKHLASGSMDSTLMIWHMKSQSRAYRFTGH 60
            +A P+   P ++        A   +  S + K   S   D  + +W + +Q+   +F GH
Sbjct: 1671 LATPT---PRIKAELTSSAPACYALAISPDGKVCFSCCSDGNIAVWDLHNQTLVRQFQGH 1501

Query: 61   KDAVTCVNFSPSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSLVT 120
             D  +C++ SP G  L +G  D TVR W    +G        ++ + S+ +C  G+ L  
Sbjct: 1500 TDGASCIDISPDGTKLWTGGLDNTVRSWDLR-EGRQLQQHDFSSQIFSLGYCPTGEWLAV 1324

Query: 121  ASDDKTVKVWSTHRQRFLFSLTQHINWVRCAKFSPDGRLIVSASDDKTVKLW 172
              +   V+V   H +   + L  H + V   KF+  G+  VS   D  +  W
Sbjct: 1323 GMESSNVEV-LHHSKPDKYQLHLHESCVLSLKFAYCGKWFVSTGKDNLLNAW 1171
>27465
          Length = 658

 Score = 82.4 bits (202), Expect = 3e-16,   Method: Compositional matrix adjust.
 Identities = 45/121 (37%), Positives = 61/121 (50%), Gaps = 1/121 (0%)
 Frame = -1

Query: 98  VFRAHTATVRSVHFCSDGQSLVTASDDKTVKVWSTHRQRFLFSLTQHINWVRCAKFS-PD 156
           V RAH   + +V F   G S +T S D+T K+W T     L +L  H N V    F+ P 
Sbjct: 376 VLRAHILPLTNVAFNKSGSSFITGSYDRTCKIWDTASAEELHTLEGHRNVVYAIAFNNPF 197

Query: 157 GRLIVSASDDKTVKLWDKTSRECIHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDA 216
           G  +++ S DKT KLW     +C H+   H   +  V F+PS T IA   MD T ++WD 
Sbjct: 196 GDKVITGSFDKTCKLWSTADGKCYHTLRGHTAEIVCVSFNPSSTLIATGSMDTTCRLWDV 17

Query: 217 R 217
            
Sbjct: 16  E 14

 Score = 63.2 bits (152), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 42/161 (26%), Positives = 75/161 (46%), Gaps = 11/161 (6%)
 Frame = -1

Query: 113 SDGQSLVTASDDKTVKVWSTHRQR---------FLFS-LTQHINWVRCAKFSPDGRLIVS 162
           ++ + L+T S  + VK W    ++         +LF  L  HI  +    F+  G   ++
Sbjct: 487 AEKEQLITPSKQEHVKNWCFACRKTRPKDDHHFYLFKVLRAHILPLTNVAFNKSGSSFIT 308

Query: 163 ASDDKTVKLWDKTSRECIHSYCEHGGFVTYVDFH-PSGTCIAAAGMDNTVKVWDARTHRL 221
            S D+T K+WD  S E +H+   H   V  + F+ P G  +     D T K+W     + 
Sbjct: 307 GSYDRTCKIWDTASAEELHTLEGHRNVVYAIAFNNPFGDKVITGSFDKTCKLWSTADGKC 128

Query: 222 LQHYQLHSAAVNALSFHPSGNYLITASSDSTLKILDLMEGR 262
               + H+A +  +SF+PS   + T S D+T ++ D+ + +
Sbjct: 127 YHTLRGHTAEIVCVSFNPSSTLIATGSMDTTCRLWDVEKAQ 5

 Score = 57.4 bits (137), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 37/135 (27%), Positives = 58/135 (42%), Gaps = 7/135 (5%)
 Frame = -1

Query: 9   PSLERHF------KGHRDAVTCVDFSLNTKHLASGSMDSTLMIWHMKSQSRAYRFTGHKD 62
           P  + HF      + H   +T V F+ +     +GS D T  IW   S    +   GH++
Sbjct: 409 PKDDHHFYLFKVLRAHILPLTNVAFNKSGSSFITGSYDRTCKIWDTASAEELHTLEGHRN 230

Query: 63  AVTCVNF-SPSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSLVTA 121
            V  + F +P G  + +GS DKT ++W           R HTA +  V F      + T 
Sbjct: 229 VVYAIAFNNPFGDKVITGSFDKTCKLWSTADGKCYHTLRGHTAEIVCVSFNPSSTLIATG 50

Query: 122 SDDKTVKVWSTHRQR 136
           S D T ++W   + +
Sbjct: 49  SMDTTCRLWDVEKAQ 5

 Score = 44.3 bits (103), Expect = 9e-05,   Method: Compositional matrix adjust.
 Identities = 24/81 (29%), Positives = 40/81 (49%), Gaps = 1/81 (1%)
 Frame = -1

Query: 221 LLQHYQLHSAAVNALSFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFS 280
           L +  + H   +  ++F+ SG+  IT S D T KI D      L+TL GH+     +AF+
Sbjct: 385 LFKVLRAHILPLTNVAFNKSGSSFITGSYDRTCKIWDTASAEELHTLEGHRNVVYAIAFN 206

Query: 281 RT-GEYFASGGSDEQVMVWKS 300
              G+   +G  D+   +W +
Sbjct: 205 NPFGDKVITGSFDKTCKLWST 143

 Score = 35.0 bits (79), Expect = 0.057,   Method: Compositional matrix adjust.
 Identities = 13/39 (33%), Positives = 24/39 (61%)
 Frame = -1

Query: 15  FKGHRDAVTCVDFSLNTKHLASGSMDSTLMIWHMKSQSR 53
            +GH   + CV F+ ++  +A+GSMD+T  +W ++   R
Sbjct: 118 LRGHTAEIVCVSFNPSSTLIATGSMDTTCRLWDVEKAQR 2
>01327
          Length = 2215

 Score = 81.6 bits (200), Expect = 6e-16,   Method: Compositional matrix adjust.
 Identities = 58/232 (25%), Positives = 102/232 (43%), Gaps = 8/232 (3%)
 Frame = +3

Query: 36  SGSMDSTLMIWHMKSQSRAYRFTGHKDAVTCVNFSPSGHLLASGSRDKTVRIWVPNVKGE 95
           SGS D +++++  ++     R+TGH   +T V +  S + + S SRDKT+++W       
Sbjct: 90  SGSKDKSVVLYDYQNGRLEDRWTGHDREITKVCYGASCNGMFSASRDKTIKMWQRGNSHS 269

Query: 96  STVFRAHTATVRSVHFCSDGQSLVTASDDKTVKVWSTHRQRFLFSLTQHINWVRCAKFSP 155
              F  H   V ++H  +D   L + S D TV++W       L       N V   K+ P
Sbjct: 270 IRDFIGHDMVVTAIHLNTDNTLLCSGSRDNTVRIWDVETGACLRQNNIPQNLVTDVKWLP 449

Query: 156 DGRLIVSASDDKTVKLWDKTSRECIHSYCEHGGFVTYVDFHPSG----TCIAAAGMDNT- 210
              LI+ A +DK V+++D  +   + S+ +        D    G    TC    G +   
Sbjct: 450 GSHLIIQAGEDKEVRIYDSRTLGIVRSFTKKQYIQMSCDVTADGQFCLTCSNGFGGNGCE 629

Query: 211 VKVWDARTHRLLQHYQLHSAAVNALSFHPSGN---YLITASSDSTLKILDLM 259
             +W      +   ++ H  A+ A  F PS      + TAS D ++++ ++ 
Sbjct: 630 ATLWQLSDGSIQNEFKGHREAIEACLFLPSNQDMTLIATASRDCSVRVWNMF 785

 Score = 65.5 bits (158), Expect = 3e-11,   Method: Compositional matrix adjust.
 Identities = 53/233 (22%), Positives = 92/233 (39%), Gaps = 8/233 (3%)
 Frame = +3

Query: 75  LLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSLVTASDDKTVKVWSTHR 134
           L  SGS+DK+V ++          +  H   +  V + +    + +AS DKT+K+W    
Sbjct: 81  LCLSGSKDKSVVLYDYQNGRLEDRWTGHDREITKVCYGASCNGMFSASRDKTIKMWQRGN 260

Query: 135 QRFLFSLTQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKTSRECIHSYCEHGGFVTYVD 194
              +     H   V     + D  L+ S S D TV++WD  +  C+         VT V 
Sbjct: 261 SHSIRDFIGHDMVVTAIHLNTDNTLLCSGSRDNTVRIWDVETGACLRQNNIPQNLVTDVK 440

Query: 195 FHPSGTCIAAAGMDNTVKVWDARTHRLLQHYQLHSAAVNALSFHPSGNYLITAS-----S 249
           + P    I  AG D  V+++D+RT  +++ +        +      G + +T S     +
Sbjct: 441 WLPGSHLIIQAGEDKEVRIYDSRTLGIVRSFTKKQYIQMSCDVTADGQFCLTCSNGFGGN 620

Query: 250 DSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGE---YFASGGSDEQVMVWK 299
                +  L +G +     GH+       F  + +     A+   D  V VW 
Sbjct: 621 GCEATLWQLSDGSIQNEFKGHREAIEACLFLPSNQDMTLIATASRDCSVRVWN 779

 Score = 65.5 bits (158), Expect = 4e-11,   Method: Compositional matrix adjust.
 Identities = 54/224 (24%), Positives = 90/224 (40%), Gaps = 8/224 (3%)
 Frame = +3

Query: 7   EDPSLERHFKGHRDAVTCVDFSLNTKHLASGSMDSTLMIWHMKSQSRAYRFTGHKDAVTC 66
           ++  LE  + GH   +T V +  +   + S S D T+ +W   +      F GH   VT 
Sbjct: 129 QNGRLEDRWTGHDREITKVCYGASCNGMFSASRDKTIKMWQRGNSHSIRDFIGHDMVVTA 308

Query: 67  VNFSPSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSLVTASDDKT 126
           ++ +    LL SGSRD TVRIW                 V  V +      ++ A +DK 
Sbjct: 309 IHLNTDNTLLCSGSRDNTVRIWDVETGACLRQNNIPQNLVTDVKWLPGSHLIIQAGEDKE 488

Query: 127 VKVWSTHRQRFLFSLTQHINWVRCAKFSPDGRLIVSAS-----DDKTVKLWDKTSRECIH 181
           V+++ +     + S T+          + DG+  ++ S     +     LW  +     +
Sbjct: 489 VRIYDSRTLGIVRSFTKKQYIQMSCDVTADGQFCLTCSNGFGGNGCEATLWQLSDGSIQN 668

Query: 182 SYCEHGGFVTYVDFHPSG---TCIAAAGMDNTVKVWDARTHRLL 222
            +  H   +    F PS    T IA A  D +V+VW+  T   +
Sbjct: 669 EFKGHREAIEACLFLPSNQDMTLIATASRDCSVRVWNMFTKECV 800

 Score = 62.4 bits (150), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 49/182 (26%), Positives = 77/182 (42%), Gaps = 8/182 (4%)
 Frame = +3

Query: 13  RHFKGHRDAVTCVDFSLNTKHLASGSMDSTLMIWHMKSQSRAYRFTGHKDAVTCVNFSPS 72
           R F GH   VT +  + +   L SGS D+T+ IW +++ +   +    ++ VT V + P 
Sbjct: 273 RDFIGHDMVVTAIHLNTDNTLLCSGSRDNTVRIWDVETGACLRQNNIPQNLVTDVKWLPG 452

Query: 73  GHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSLVTASDD-----KTV 127
            HL+     DK VRI+     G    F        S    +DGQ  +T S+         
Sbjct: 453 SHLIIQAGEDKEVRIYDSRTLGIVRSFTKKQYIQMSCDVTADGQFCLTCSNGFGGNGCEA 632

Query: 128 KVWSTHRQRFLFSLTQHINWVRCAKFSP---DGRLIVSASDDKTVKLWDKTSRECIHSYC 184
            +W             H   +    F P   D  LI +AS D +V++W+  ++EC+   C
Sbjct: 633 TLWQLSDGSIQNEFKGHREAIEACLFLPSNQDMTLIATASRDCSVRVWNMFTKECV---C 803

Query: 185 EH 186
           E 
Sbjct: 804 EQ 809

 Score = 32.7 bits (73), Expect = 0.30,   Method: Compositional matrix adjust.
 Identities = 22/71 (30%), Positives = 36/71 (50%), Gaps = 3/71 (4%)
 Frame = +3

Query: 8   DPSLERHFKGHRDAVTCVDF---SLNTKHLASGSMDSTLMIWHMKSQSRAYRFTGHKDAV 64
           D S++  FKGHR+A+    F   + +   +A+ S D ++ +W+M        FT  K+ V
Sbjct: 651 DGSIQNEFKGHREAIEACLFLPSNQDMTLIATASRDCSVRVWNM--------FT--KECV 800

Query: 65  TCVNFSPSGHL 75
              NF  +G L
Sbjct: 801 CEQNFEGTGPL 833
>12960
          Length = 550

 Score = 80.9 bits (198), Expect = 9e-16,   Method: Compositional matrix adjust.
 Identities = 44/113 (38%), Positives = 63/113 (55%)
 Frame = +2

Query: 106 VRSVHFCSDGQSLVTASDDKTVKVWSTHRQRFLFSLTQHINWVRCAKFSPDGRLIVSASD 165
           VR+V F  D +  +T   DK+VK+W+ HR+ FL +   H + V  A+ S D   I S   
Sbjct: 182 VRAVRFSVDSRYCMTCGSDKSVKLWNPHRELFLKTYIGHGHEVLDAQGSGDNSQICSGGI 361

Query: 166 DKTVKLWDKTSRECIHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDART 218
           DKTV L+D  S + +  Y +H G V  V F+   T I +  +DNTV+ WD R+
Sbjct: 362 DKTVVLFDVASGQALRKYRDHAGTVNCVKFNEESTVILSGSLDNTVRAWDTRS 520

 Score = 61.6 bits (148), Expect = 6e-10,   Method: Compositional matrix adjust.
 Identities = 32/110 (29%), Positives = 57/110 (51%)
 Frame = +2

Query: 148 VRCAKFSPDGRLIVSASDDKTVKLWDKTSRECIHSYCEHGGFVTYVDFHPSGTCIAAAGM 207
           VR  +FS D R  ++   DK+VKLW+      + +Y  HG  V         + I + G+
Sbjct: 182 VRAVRFSVDSRYCMTCGSDKSVKLWNPHRELFLKTYIGHGHEVLDAQGSGDNSQICSGGI 361

Query: 208 DNTVKVWDARTHRLLQHYQLHSAAVNALSFHPSGNYLITASSDSTLKILD 257
           D TV ++D  + + L+ Y+ H+  VN + F+     +++ S D+T++  D
Sbjct: 362 DKTVVLFDVASGQALRKYRDHAGTVNCVKFNEESTVILSGSLDNTVRAWD 511

 Score = 53.1 bits (126), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 33/117 (28%), Positives = 51/117 (43%)
 Frame = +2

Query: 61  KDAVTCVNFSPSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSLVT 120
           + AV  V FS       +   DK+V++W P+ +     +  H   V       D   + +
Sbjct: 173 QQAVRAVRFSVDSRYCMTCGSDKSVKLWNPHRELFLKTYIGHGHEVLDAQGSGDNSQICS 352

Query: 121 ASDDKTVKVWSTHRQRFLFSLTQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKTSR 177
              DKTV ++     + L     H   V C KF+ +  +I+S S D TV+ WD  SR
Sbjct: 353 GGIDKTVVLFDVASGQALRKYRDHAGTVNCVKFNEESTVILSGSLDNTVRAWDTRSR 523

 Score = 44.7 bits (104), Expect = 7e-05,   Method: Compositional matrix adjust.
 Identities = 29/112 (25%), Positives = 50/112 (44%)
 Frame = +2

Query: 21  AVTCVDFSLNTKHLASGSMDSTLMIWHMKSQSRAYRFTGHKDAVTCVNFSPSGHLLASGS 80
           AV  V FS+++++  +   D ++ +W+   +     + GH   V     S     + SG 
Sbjct: 179 AVRAVRFSVDSRYCMTCGSDKSVKLWNPHRELFLKTYIGHGHEVLDAQGSGDNSQICSGG 358

Query: 81  RDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSLVTASDDKTVKVWST 132
            DKTV ++          +R H  TV  V F  +   +++ S D TV+ W T
Sbjct: 359 IDKTVVLFDVASGQALRKYRDHAGTVNCVKFNEESTVILSGSLDNTVRAWDT 514

 Score = 43.9 bits (102), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 22/74 (29%), Positives = 36/74 (48%)
 Frame = +2

Query: 15  FKGHRDAVTCVDFSLNTKHLASGSMDSTLMIWHMKSQSRAYRFTGHKDAVTCVNFSPSGH 74
           + GH   V     S +   + SG +D T++++ + S     ++  H   V CV F+    
Sbjct: 287 YIGHGHEVLDAQGSGDNSQICSGGIDKTVVLFDVASGQALRKYRDHAGTVNCVKFNEEST 466

Query: 75  LLASGSRDKTVRIW 88
           ++ SGS D TVR W
Sbjct: 467 VILSGSLDNTVRAW 508

 Score = 33.9 bits (76), Expect = 0.11,   Method: Compositional matrix adjust.
 Identities = 14/40 (35%), Positives = 24/40 (60%)
 Frame = +2

Query: 13  RHFKGHRDAVTCVDFSLNTKHLASGSMDSTLMIWHMKSQS 52
           R ++ H   V CV F+  +  + SGS+D+T+  W  +S+S
Sbjct: 407 RKYRDHAGTVNCVKFNEESTVILSGSLDNTVRAWDTRSRS 526

 Score = 30.0 bits (66), Expect = 1.9,   Method: Compositional matrix adjust.
 Identities = 19/59 (32%), Positives = 28/59 (47%), Gaps = 2/59 (3%)
 Frame = -1

Query: 74  HLLASG--SRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSLVTASDDKTVKVW 130
           HL+A      +K   +W+P +    T  R   +TV +   CSDG  L+ A D   + VW
Sbjct: 310 HLMAVSYVGLEKEFSVWIPQLDRLITAARHAVSTVNTEANCSDG--LLLAIDGNLLSVW 140
>12574
          Length = 521

 Score = 80.5 bits (197), Expect = 1e-15,   Method: Compositional matrix adjust.
 Identities = 44/111 (39%), Positives = 63/111 (56%), Gaps = 1/111 (0%)
 Frame = +3

Query: 55  YRFTGHKDAVTCVNFSPSGHLLASGSRDKTVRIW-VPNVKGESTVFRAHTATVRSVHFCS 113
           +   GH  A++ V FSP+G  LAS S DK ++IW   + K E T+   H   +  V + S
Sbjct: 168 FTLAGHTKALSAVKFSPNGDWLASSSADKLIKIWGAYDGKFEKTI-AGHKLGLSDVAWSS 344

Query: 114 DGQSLVTASDDKTVKVWSTHRQRFLFSLTQHINWVRCAKFSPDGRLIVSAS 164
           D + L +ASDDKT+K+W     + + +L  H N+V C  F+P   LIVS S
Sbjct: 345 DSKLLCSASDDKTLKIWEFSTGKCMKTLKGHSNYVFCCNFNPQSNLIVSGS 497

 Score = 67.0 bits (162), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 31/107 (28%), Positives = 59/107 (55%)
 Frame = +3

Query: 101 AHTATVRSVHFCSDGQSLVTASDDKTVKVWSTHRQRFLFSLTQHINWVRCAKFSPDGRLI 160
            HT  + +V F  +G  L ++S DK +K+W  +  +F  ++  H   +    +S D +L+
Sbjct: 180 GHTKALSAVKFSPNGDWLASSSADKLIKIWGAYDGKFEKTIAGHKLGLSDVAWSSDSKLL 359

Query: 161 VSASDDKTVKLWDKTSRECIHSYCEHGGFVTYVDFHPSGTCIAAAGM 207
            SASDDKT+K+W+ ++ +C+ +   H  +V   +F+P    I +  +
Sbjct: 360 CSASDDKTLKIWEFSTGKCMKTLKGHSNYVFCCNFNPQSNLIVSGSL 500

 Score = 55.1 bits (131), Expect = 5e-08,   Method: Compositional matrix adjust.
 Identities = 29/110 (26%), Positives = 55/110 (50%)
 Frame = +3

Query: 139 FSLTQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKTSRECIHSYCEHGGFVTYVDFHPS 198
           F+L  H   +   KFSP+G  + S+S DK +K+W     +   +   H   ++ V +   
Sbjct: 168 FTLAGHTKALSAVKFSPNGDWLASSSADKLIKIWGAYDGKFEKTIAGHKLGLSDVAWSSD 347

Query: 199 GTCIAAAGMDNTVKVWDARTHRLLQHYQLHSAAVNALSFHPSGNYLITAS 248
              + +A  D T+K+W+  T + ++  + HS  V   +F+P  N +++ S
Sbjct: 348 SKLLCSASDDKTLKIWEFSTGKCMKTLKGHSNYVFCCNFNPQSNLIVSGS 497

 Score = 50.4 bits (119), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 26/73 (35%), Positives = 38/73 (52%)
 Frame = +3

Query: 8   DPSLERHFKGHRDAVTCVDFSLNTKHLASGSMDSTLMIWHMKSQSRAYRFTGHKDAVTCV 67
           D   E+   GH+  ++ V +S ++K L S S D TL IW   +        GH + V C 
Sbjct: 279 DGKFEKTIAGHKLGLSDVAWSSDSKLLCSASDDKTLKIWEFSTGKCMKTLKGHSNYVFCC 458

Query: 68  NFSPSGHLLASGS 80
           NF+P  +L+ SGS
Sbjct: 459 NFNPQSNLIVSGS 497

 Score = 49.7 bits (117), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 27/104 (25%), Positives = 47/104 (45%)
 Frame = +3

Query: 186 HGGFVTYVDFHPSGTCIAAAGMDNTVKVWDARTHRLLQHYQLHSAAVNALSFHPSGNYLI 245
           H   ++ V F P+G  +A++  D  +K+W A   +  +    H   ++ +++      L 
Sbjct: 183 HTKALSAVKFSPNGDWLASSSADKLIKIWGAYDGKFEKTIAGHKLGLSDVAWSSDSKLLC 362

Query: 246 TASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGEYFASG 289
           +AS D TLKI +   G+ + TL GH        F+       SG
Sbjct: 363 SASDDKTLKIWEFSTGKCMKTLKGHSNYVFCCNFNPQSNLIVSG 494

 Score = 48.1 bits (113), Expect = 6e-06,   Method: Compositional matrix adjust.
 Identities = 21/72 (29%), Positives = 43/72 (59%)
 Frame = +3

Query: 228 HSAAVNALSFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGEYFA 287
           H+ A++A+ F P+G++L ++S+D  +KI    +G+   T+ GH+   + VA+S   +   
Sbjct: 183 HTKALSAVKFSPNGDWLASSSADKLIKIWGAYDGKFEKTIAGHKLGLSDVAWSSDSKLLC 362

Query: 288 SGGSDEQVMVWK 299
           S   D+ + +W+
Sbjct: 363 SASDDKTLKIWE 398

 Score = 32.7 bits (73), Expect = 0.30,   Method: Compositional matrix adjust.
 Identities = 13/36 (36%), Positives = 21/36 (58%)
 Frame = +3

Query: 263 LLYTLHGHQGPATTVAFSRTGEYFASGGSDEQVMVW 298
           L +TL GH    + V FS  G++ AS  +D+ + +W
Sbjct: 162 LKFTLAGHTKALSAVKFSPNGDWLASSSADKLIKIW 269
>17602
          Length = 481

 Score = 71.2 bits (173), Expect = 7e-13,   Method: Compositional matrix adjust.
 Identities = 43/134 (32%), Positives = 69/134 (51%), Gaps = 4/134 (2%)
 Frame = +3

Query: 86  RIWVPNVKGESTVFRAHTATVRSVHFCSDGQSLVTASDDKTVKVWSTHRQRFLFSLTQHI 145
           RIW            AH+  V +VHF  DG  +V++S D   ++W T   + L +L    
Sbjct: 3   RIWDVKTGKCLKTLPAHSDPVTAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLXTLIDDD 182

Query: 146 NW-VRCAKFSPDGRLIVSASDDKTVKLWDKTSRECIHSYCEHGG--FVTYVDFHPS-GTC 201
           N  V   KFSP+G+ I++A+ D T+KLWD +  +C+ +Y  H    +  + +F  + G  
Sbjct: 183 NPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYVGHRNEKYCIFANFSVTGGKW 362

Query: 202 IAAAGMDNTVKVWD 215
           I +   DN V +W+
Sbjct: 363 IVSGSEDNMVYIWN 404

 Score = 71.2 bits (173), Expect = 8e-13,   Method: Compositional matrix adjust.
 Identities = 42/144 (29%), Positives = 75/144 (52%), Gaps = 4/144 (2%)
 Frame = +3

Query: 170 KLWDKTSRECIHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDARTHRLLQHY-QLH 228
           ++WD  + +C+ +   H   VT V F+  G+ I ++  D   ++WD  + + L       
Sbjct: 3   RIWDVKTGKCLKTLPAHSDPVTAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLXTLIDDD 182

Query: 229 SAAVNALSFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATTV--AFSRT-GEY 285
           +  V+ + F P+G Y++ A+ D+TLK+ D  +G+ L T  GH+     +   FS T G++
Sbjct: 183 NPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYVGHRNEKYCIFANFSVTGGKW 362

Query: 286 FASGGSDEQVMVWKSNFDIVDYGD 309
             SG  D  V +W    +++D GD
Sbjct: 363 IVSGSEDNMVYIW----NLLDQGD 422

 Score = 62.0 bits (149), Expect = 4e-10,   Method: Compositional matrix adjust.
 Identities = 42/133 (31%), Positives = 64/133 (48%), Gaps = 4/133 (3%)
 Frame = +3

Query: 45  IWHMKSQSRAYRFTGHKDAVTCVNFSPSGHLLASGSRDKTVRIW-VPNVKGESTVFRAHT 103
           IW +K+         H D VT V+F+  G L+ S S D   RIW   + +   T+     
Sbjct: 6   IWDVKTGKCLKTLPAHSDPVTAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLXTLIDDDN 185

Query: 104 ATVRSVHFCSDGQSLVTASDDKTVKVWSTHRQRFLFSLTQHINWVRC--AKFS-PDGRLI 160
             V  V F  +G+ ++ A+ D T+K+W   + + L +   H N   C  A FS   G+ I
Sbjct: 186 PPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYVGHRNEKYCIFANFSVTGGKWI 365

Query: 161 VSASDDKTVKLWD 173
           VS S+D  V +W+
Sbjct: 366 VSGSEDNMVYIWN 404

 Score = 46.6 bits (109), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 27/79 (34%), Positives = 43/79 (54%), Gaps = 3/79 (3%)
 Frame = +3

Query: 22  VTCVDFSLNTKHLASGSMDSTLMIWHMKSQSRAYRFTGHKDAVTCV--NFSPSG-HLLAS 78
           V+ V FS N K++ + ++D+TL +W          + GH++   C+  NFS +G   + S
Sbjct: 192 VSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYVGHRNEKYCIFANFSVTGGKWIVS 371

Query: 79  GSRDKTVRIWVPNVKGEST 97
           GS D  V IW    +G+ST
Sbjct: 372 GSEDNMVYIWNLLDQGDST 428

 Score = 42.7 bits (99), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 32/131 (24%), Positives = 55/131 (41%), Gaps = 8/131 (6%)
 Frame = +3

Query: 13  RHFKGHRDAVTCVDFSLNTKHLASGSMDSTLMIWHMKS-QSRAYRFTGHKDAVTCVNFSP 71
           +    H D VT V F+ +   + S S D    IW   S Q            V+ V FSP
Sbjct: 36  KTLPAHSDPVTAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLXTLIDDDNPPVSFVKFSP 215

Query: 72  SGHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFC-------SDGQSLVTASDD 124
           +G  + + + D T+++W  +       +  H    R+  +C       + G+ +V+ S+D
Sbjct: 216 NGKYILAATLDNTLKLWDYSKGKCLKTYVGH----RNEKYCIFANFSVTGGKWIVSGSED 383

Query: 125 KTVKVWSTHRQ 135
             V +W+   Q
Sbjct: 384 NMVYIWNLLDQ 416

 Score = 31.6 bits (70), Expect = 0.59,   Method: Compositional matrix adjust.
 Identities = 19/60 (31%), Positives = 33/60 (55%), Gaps = 5/60 (8%)
 Frame = +3

Query: 13  RHFKGHRDAVTCV--DFSL-NTKHLASGSMDSTLMIWHMKSQSRAYRFTG--HKDAVTCV 67
           + + GHR+   C+  +FS+   K + SGS D+ + IW++  Q  +   TG   + AV C+
Sbjct: 291 KTYVGHRNEKYCIFANFSVTGGKWIVSGSEDNMVYIWNLLDQGDSTEATGSHRRGAVLCL 470
>03387
          Length = 1891

 Score = 68.2 bits (165), Expect = 6e-12,   Method: Compositional matrix adjust.
 Identities = 62/237 (26%), Positives = 111/237 (46%), Gaps = 31/237 (13%)
 Frame = +1

Query: 56  RFTGHKDAVTCVNFSPS--GHLLASGSRDKTVRIWVPN-------VKGESTVFRAHTATV 106
           R  GH+     ++++P+  GHLL S S D T+ +W  N       V    T+F  HT+ V
Sbjct: 346 RLKGHQKEGYGLSWNPNLNGHLL-SASDDHTICLWDINSTQRESRVVDAHTIFTGHTSVV 522

Query: 107 RSVHFCSDGQSLV-TASDDKTVKVWSTHRQ---RFLFSLTQHINWVRCAKFSPDGRLIVS 162
             V +    +SL  + +DD+ + +W T      +    +  H   V C  F+P    I++
Sbjct: 523 EDVAWHLLHESLFGSVADDQKLMIWDTRSNTTSKPSHVVDAHTAEVNCLSFNPYSEFILA 702

Query: 163 -ASDDKTVKLWD-KTSRECIHSYCEHGGFVTYVDFHP-SGTCIAAAGMDNTVKVWDART- 218
             S DKTV LWD +  +  +HS+  H   +  V + P + T +A++G D  + VWD    
Sbjct: 703 TGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLHVWDLSKI 882

Query: 219 -------------HRLLQHYQLHSAAVNALSFHPSGNYLI-TASSDSTLKILDLMEG 261
                          LL  +  H+A ++  S++P+  +++ + S D+ +++  + E 
Sbjct: 883 GEEQLPEDAEDGPPELLFIHGGHTAKISDFSWNPNEPWIVCSVSEDNIMQVWQMAEN 1053

 Score = 56.2 bits (134), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 47/153 (30%), Positives = 77/153 (50%), Gaps = 14/153 (9%)
 Frame = +1

Query: 160 IVSASDDKTVKLWD--KTSREC----IHS-YCEHGGFVTYVDFH-PSGTCIAAAGMDNTV 211
           ++SASDD T+ LWD   T RE      H+ +  H   V  V +H    +   +   D  +
Sbjct: 409 LLSASDDHTICLWDINSTQRESRVVDAHTIFTGHTSVVEDVAWHLLHESLFGSVADDQKL 588

Query: 212 KVWDARTHRLLQHYQL---HSAAVNALSFHPSGNYLI-TASSDSTLKILDLMEGRL-LYT 266
            +WD R++   +   +   H+A VN LSF+P   +++ T S+D T+ + DL   +L L++
Sbjct: 589 MIWDTRSNTTSKPSHVVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHS 768

Query: 267 LHGHQGPATTVAFSRTGE-YFASGGSDEQVMVW 298
              H+     V +S   E   AS G+D ++ VW
Sbjct: 769 FESHKDEIFQVQWSPHNETILASSGTDRRLHVW 867
>00825
          Length = 1821

 Score = 65.9 bits (159), Expect = 3e-11,   Method: Compositional matrix adjust.
 Identities = 60/271 (22%), Positives = 115/271 (42%), Gaps = 6/271 (2%)
 Frame = -2

Query: 36   SGSMDSTLMIWHMKSQSRAYRFTGHKDAVTCVNFSPSGHLLASGSRDKTVRIWVPNVKGE 95
            SG+ D  L+ W++  Q  A R   H   V  +    SG    S   DKT++ W  + +G 
Sbjct: 1820 SGACDGELICWNLPKQQMACRVQAHDGIVHGMAAHSSGQYFFSCGSDKTIKQWSLDPEGT 1641

Query: 96   STVFRAHTATVRSVHFCSD--GQSLVTASDDKTVKVWSTHRQRFLFSLTQHINWVRCAKF 153
                  +T   + ++   D   +  +  +    V VW   R   + S +  +  V   KF
Sbjct: 1640 IAPEPVNTLLAKCIYTSLDHHWKDDIFVTSGSRVDVWDEKRSEPMRSFSWGVESVHHVKF 1461

Query: 154  SP-DGRLIVSASDDKTVKLWDKTSRECIHSYCEHGGFVTYVDFHP-SGTCIAAAGMDNTV 211
            +P +  L+ +A+ D+++ L+D      +            + ++P     I +A  D  +
Sbjct: 1460 NPVETYLLGAAAHDRSILLYDMRGSAPLRKVVMKMR-TNALSWNPMEAFTITSANEDGNL 1284

Query: 212  KVWDARTHRL-LQHYQLHSAAVNALSFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGH 270
              +D R   + L  ++ H+AAV  + + P+G   ++A  D  ++I  + +G      H  
Sbjct: 1283 YTFDMRKLSMPLNMHRDHTAAVMDVDYCPTGREFVSAGYDKVIRIFPVDKGHSREVYHTK 1104

Query: 271  Q-GPATTVAFSRTGEYFASGGSDEQVMVWKS 300
            +     +V +SR  +Y  S   +  + VWK+
Sbjct: 1103 RMQRVGSVVWSRDSKYIFSASDEMNIRVWKA 1011

 Score = 43.5 bits (101), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 24/83 (28%), Positives = 44/83 (53%), Gaps = 2/83 (2%)
 Frame = -2

Query: 100  RAHTATVRSVHFCSDGQSLVTASDDKTVKVWSTHR--QRFLFSLTQHINWVRCAKFSPDG 157
            R HTA V  V +C  G+  V+A  DK ++++   +   R ++  T+ +  V    +S D 
Sbjct: 1238 RDHTAAVMDVDYCPTGREFVSAGYDKVIRIFPVDKGHSREVYH-TKRMQRVGSVVWSRDS 1062

Query: 158  RLIVSASDDKTVKLWDKTSRECI 180
            + I SASD+  +++W   + E +
Sbjct: 1061 KYIFSASDEMNIRVWKAVAWEAL 993
>03156
          Length = 1014

 Score = 65.1 bits (157), Expect = 5e-11,   Method: Compositional matrix adjust.
 Identities = 54/220 (24%), Positives = 88/220 (40%), Gaps = 8/220 (3%)
 Frame = +1

Query: 11  LERHFKGHRDAVTCVDFSLNTKHLASGSMDSTLMIWHMKSQSRAYRFTGHKDAVTCVNFS 70
           LE  + GH   +T V +  +   + S S D T+ +W   +      F GH   VT ++ +
Sbjct: 31  LEDRWTGHDREITKVCYGASCNGMFSASRDKTIKMWQRGNSHSIRDFIGHDMVVTAIHLN 210

Query: 71  PSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSLVTASDDKTVKVW 130
               LL SGSRD TVRIW                 V  V +      ++ A +DK V+++
Sbjct: 211 TDNTLLCSGSRDNTVRIWDVETGACLRQNNIPQNLVTDVKWLPGSHLIIQAGEDKEVRIY 390

Query: 131 STHRQRFLFSLTQHINWVRCAKFSPDGRLIVSAS-----DDKTVKLWDKTSRECIHSYCE 185
            +     + S T+          + DG+  ++ S     +     LW  +     + +  
Sbjct: 391 DSRTLGIVRSFTKKQYIQMSCDVTADGQFCLTCSNGFGGNGCEATLWQLSDGSIQNEFKG 570

Query: 186 HGGFVTYVDFHPSG---TCIAAAGMDNTVKVWDARTHRLL 222
           H   +    F PS    T IA A  D +V+VW+  T   +
Sbjct: 571 HREAIEACLFLPSNQDMTLIATASRDCSVRVWNMFTKECV 690

 Score = 62.4 bits (150), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 49/182 (26%), Positives = 77/182 (42%), Gaps = 8/182 (4%)
 Frame = +1

Query: 13  RHFKGHRDAVTCVDFSLNTKHLASGSMDSTLMIWHMKSQSRAYRFTGHKDAVTCVNFSPS 72
           R F GH   VT +  + +   L SGS D+T+ IW +++ +   +    ++ VT V + P 
Sbjct: 163 RDFIGHDMVVTAIHLNTDNTLLCSGSRDNTVRIWDVETGACLRQNNIPQNLVTDVKWLPG 342

Query: 73  GHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSLVTASDD-----KTV 127
            HL+     DK VRI+     G    F        S    +DGQ  +T S+         
Sbjct: 343 SHLIIQAGEDKEVRIYDSRTLGIVRSFTKKQYIQMSCDVTADGQFCLTCSNGFGGNGCEA 522

Query: 128 KVWSTHRQRFLFSLTQHINWVRCAKFSP---DGRLIVSASDDKTVKLWDKTSRECIHSYC 184
            +W             H   +    F P   D  LI +AS D +V++W+  ++EC+   C
Sbjct: 523 TLWQLSDGSIQNEFKGHREAIEACLFLPSNQDMTLIATASRDCSVRVWNMFTKECV---C 693

Query: 185 EH 186
           E 
Sbjct: 694 EQ 699

 Score = 60.1 bits (144), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 46/207 (22%), Positives = 80/207 (38%), Gaps = 8/207 (3%)
 Frame = +1

Query: 101 AHTATVRSVHFCSDGQSLVTASDDKTVKVWSTHRQRFLFSLTQHINWVRCAKFSPDGRLI 160
            H   +  V + +    + +AS DKT+K+W       +     H   V     + D  L+
Sbjct: 49  GHDREITKVCYGASCNGMFSASRDKTIKMWQRGNSHSIRDFIGHDMVVTAIHLNTDNTLL 228

Query: 161 VSASDDKTVKLWDKTSRECIHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDARTHR 220
            S S D TV++WD  +  C+         VT V + P    I  AG D  V+++D+RT  
Sbjct: 229 CSGSRDNTVRIWDVETGACLRQNNIPQNLVTDVKWLPGSHLIIQAGEDKEVRIYDSRTLG 408

Query: 221 LLQHYQLHSAAVNALSFHPSGNYLITAS-----SDSTLKILDLMEGRLLYTLHGHQGPAT 275
           +++ +        +      G + +T S     +     +  L +G +     GH+    
Sbjct: 409 IVRSFTKKQYIQMSCDVTADGQFCLTCSNGFGGNGCEATLWQLSDGSIQNEFKGHREAIE 588

Query: 276 TVAFSRTGE---YFASGGSDEQVMVWK 299
              F  + +     A+   D  V VW 
Sbjct: 589 ACLFLPSNQDMTLIATASRDCSVRVWN 669

 Score = 32.7 bits (73), Expect = 0.25,   Method: Compositional matrix adjust.
 Identities = 18/83 (21%), Positives = 32/83 (38%)
 Frame = +1

Query: 216 ARTHRLLQHYQLHSAAVNALSFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPAT 275
           ++  RL   +  H   +  + +  S N + +AS D T+K+        +    GH    T
Sbjct: 16  SKMGRLEDRWTGHDREITKVCYGASCNGMFSASRDKTIKMWQRGNSHSIRDFIGHDMVVT 195

Query: 276 TVAFSRTGEYFASGGSDEQVMVW 298
            +  +       SG  D  V +W
Sbjct: 196 AIHLNTDNTLLCSGSRDNTVRIW 264

 Score = 32.7 bits (73), Expect = 0.31,   Method: Compositional matrix adjust.
 Identities = 22/71 (30%), Positives = 36/71 (50%), Gaps = 3/71 (4%)
 Frame = +1

Query: 8   DPSLERHFKGHRDAVTCVDF---SLNTKHLASGSMDSTLMIWHMKSQSRAYRFTGHKDAV 64
           D S++  FKGHR+A+    F   + +   +A+ S D ++ +W+M        FT  K+ V
Sbjct: 541 DGSIQNEFKGHREAIEACLFLPSNQDMTLIATASRDCSVRVWNM--------FT--KECV 690

Query: 65  TCVNFSPSGHL 75
              NF  +G L
Sbjct: 691 CEQNFEGTGPL 723
>19498
          Length = 903

 Score = 64.3 bits (155), Expect = 8e-11,   Method: Compositional matrix adjust.
 Identities = 60/220 (27%), Positives = 87/220 (39%), Gaps = 31/220 (14%)
 Frame = -1

Query: 9   PSLERHFKGHRDAVTCVDFSLNTKHLASGSMDSTLMIWHMKSQSRAY------------- 55
           P +      H   V CV +S N K LASG  D  +MIW +   SR +             
Sbjct: 816 PRVLCQMDSHLGCVNCVRWSENGKFLASGGDDKLIMIWQI---SRGFGSGKSFGSNVTIL 646

Query: 56  -------RFTGHKDAVTCVNFSPSGHLLASGSRDKTVRIW-VPNVKGESTVFRAHTATVR 107
                     GH   V  + +SP    LAS S D T+ +W       +  V R H   V+
Sbjct: 645 EHWRSVATLRGHAGDVLDLAWSPQDLWLASCSVDNTIVVWNALKFSEQVAVIRGHAGMVK 466

Query: 108 SVHFCSDGQSLVTASDDKTVKVWSTHRQ------RFLFSLTQHINWVRCAKFSPDGRLIV 161
            V +   G+ L + SDDKT++VW T         +  F        V    +SPDG  +V
Sbjct: 465 GVTWDPVGRYLASQSDDKTLRVWRTSDWKEETCVKSCFKECGGTTHVLRLNWSPDGNHVV 286

Query: 162 SA----SDDKTVKLWDKTSRECIHSYCEHGGFVTYVDFHP 197
           SA    +   T ++ ++        +  H   +T V F+P
Sbjct: 285 SAHAMNNAXPTAQIIERNGWGTSLDFVGHRKAITVVRFNP 166

 Score = 60.1 bits (144), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 53/208 (25%), Positives = 86/208 (41%), Gaps = 28/208 (13%)
 Frame = -1

Query: 60  HKDAVTCVNFSPSGHLLASGSRDKTVRIW-VPNVKGESTVF----------------RAH 102
           H   V CV +S +G  LASG  DK + IW +    G    F                R H
Sbjct: 789 HLGCVNCVRWSENGKFLASGGDDKLIMIWQISRGFGSGKSFGSNVTILEHWRSVATLRGH 610

Query: 103 TATVRSVHFCSDGQSLVTASDDKTVKVWSTHR-QRFLFSLTQHINWVRCAKFSPDGRLIV 161
              V  + +      L + S D T+ VW+  +    +  +  H   V+   + P GR + 
Sbjct: 609 AGDVLDLAWSPQDLWLASCSVDNTIVVWNALKFSEQVAVIRGHAGMVKGVTWDPVGRYLA 430

Query: 162 SASDDKTVKLW---DKTSRECIHSYCEHGGFVTYV---DFHPSGT-CIAAAGMDN---TV 211
           S SDDKT+++W   D     C+ S  +  G  T+V   ++ P G   ++A  M+N   T 
Sbjct: 429 SQSDDKTLRVWRTSDWKEETCVKSCFKECGGTTHVLRLNWSPDGNHVVSAHAMNNAXPTA 250

Query: 212 KVWDARTHRLLQHYQLHSAAVNALSFHP 239
           ++ +         +  H  A+  + F+P
Sbjct: 249 QIIERNGWGTSLDFVGHRKAITVVRFNP 166

 Score = 57.4 bits (137), Expect = 9e-09,   Method: Compositional matrix adjust.
 Identities = 35/139 (25%), Positives = 64/139 (46%), Gaps = 19/139 (13%)
 Frame = -1

Query: 136 RFLFSLTQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKTSR------------------ 177
           R L  +  H+  V C ++S +G+ + S  DDK + +W + SR                  
Sbjct: 813 RVLCQMDSHLGCVNCVRWSENGKFLASGGDDKLIMIW-QISRGFGSGKSFGSNVTILEHW 637

Query: 178 ECIHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDA-RTHRLLQHYQLHSAAVNALS 236
             + +   H G V  + + P    +A+  +DNT+ VW+A +    +   + H+  V  ++
Sbjct: 636 RSVATLRGHAGDVLDLAWSPQDLWLASCSVDNTIVVWNALKFSEQVAVIRGHAGMVKGVT 457

Query: 237 FHPSGNYLITASSDSTLKI 255
           + P G YL + S D TL++
Sbjct: 456 WDPVGRYLASQSDDKTLRV 400

 Score = 48.5 bits (114), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 49/210 (23%), Positives = 84/210 (40%), Gaps = 30/210 (14%)
 Frame = -1

Query: 101 AHTATVRSVHFCSDGQSLVTASDDKTVKVWSTHR-----------------QRFLFSLTQ 143
           +H   V  V +  +G+ L +  DDK + +W   R                  R + +L  
Sbjct: 792 SHLGCVNCVRWSENGKFLASGGDDKLIMIWQISRGFGSGKSFGSNVTILEHWRSVATLRG 613

Query: 144 HINWVRCAKFSPDGRLIVSASDDKTVKLWDKTS-RECIHSYCEHGGFVTYVDFHPSGTCI 202
           H   V    +SP    + S S D T+ +W+     E +     H G V  V + P G  +
Sbjct: 612 HAGDVLDLAWSPQDLWLASCSVDNTIVVWNALKFSEQVAVIRGHAGMVKGVTWDPVGRYL 433

Query: 203 AAAGMDNTVKVWDARTHRLLQHYQLHSAA--------VNALSFHPSGNYLITA----SSD 250
           A+   D T++VW  RT    +   + S          V  L++ P GN++++A    ++ 
Sbjct: 432 ASQSDDKTLRVW--RTSDWKEETCVKSCFKECGGTTHVLRLNWSPDGNHVVSAHAMNNAX 259

Query: 251 STLKILDLMEGRLLYTLHGHQGPATTVAFS 280
            T +I++           GH+   T V F+
Sbjct: 258 PTAQIIERNGWGTSLDFVGHRKAITVVRFN 169

 Score = 37.4 bits (85), Expect = 0.010,   Method: Compositional matrix adjust.
 Identities = 14/38 (36%), Positives = 23/38 (60%)
 Frame = -1

Query: 262 RLLYTLHGHQGPATTVAFSRTGEYFASGGSDEQVMVWK 299
           R+L  +  H G    V +S  G++ ASGG D+ +M+W+
Sbjct: 813 RVLCQMDSHLGCVNCVRWSENGKFLASGGDDKLIMIWQ 700
>15251
          Length = 352

 Score = 63.5 bits (153), Expect = 1e-10,   Method: Composition-based stats.
 Identities = 32/64 (50%), Positives = 45/64 (70%)
 Frame = +3

Query: 342 SVQGEPQESISMPQTLTSTLEHIVGQLDILTQTVSILEQRLTLTEDRLKQCLENQQLIMQ 401
           S  G P+ S +M    +  +E I GQLDILTQTVS+LEQRLT+TE++L++C++ QQ I  
Sbjct: 48  SAAGGPRCSPAM----SKFMEQIAGQLDILTQTVSLLEQRLTMTENKLRECMDGQQEIRL 215

Query: 402 RTPP 405
           +  P
Sbjct: 216 QIKP 227
>35607
          Length = 475

 Score = 62.4 bits (150), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 32/106 (30%), Positives = 57/106 (53%)
 Frame = +2

Query: 197 PSGTCIAAAGMDNTVKVWDARTHRLLQHYQLHSAAVNALSFHPSGNYLITASSDSTLKIL 256
           P GT +   G+DNTV+ WD R  R LQ +   S+ + +L + P+G++L      S +++L
Sbjct: 8   PDGTKLWTGGLDNTVRSWDLREGRQLQQHDF-SSQIFSLGYCPTGDWLAVGMESSNVEVL 184

Query: 257 DLMEGRLLYTLHGHQGPATTVAFSRTGEYFASGGSDEQVMVWKSNF 302
              +    Y LH H+    ++ F+  G++F S G D  +  W++ +
Sbjct: 185 HHSKPD-KYQLHLHESCVLSLKFAYCGKWFVSTGKDNLLNAWRTPY 319

 Score = 33.1 bits (74), Expect = 0.20,   Method: Compositional matrix adjust.
 Identities = 27/102 (26%), Positives = 42/102 (41%)
 Frame = +2

Query: 71  PSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSLVTASDDKTVKVW 130
           P G  L +G  D TVR W    +G        ++ + S+ +C  G  L    +   V+V 
Sbjct: 8   PDGTKLWTGGLDNTVRSWDLR-EGRQLQQHDFSSQIFSLGYCPTGDWLAVGMESSNVEV- 181

Query: 131 STHRQRFLFSLTQHINWVRCAKFSPDGRLIVSASDDKTVKLW 172
             H +   + L  H + V   KF+  G+  VS   D  +  W
Sbjct: 182 LHHSKPDKYQLHLHESCVLSLKFAYCGKWFVSTGKDNLLNAW 307
>17266
          Length = 480

 Score = 62.4 bits (150), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 34/137 (24%), Positives = 61/137 (44%), Gaps = 2/137 (1%)
 Frame = -1

Query: 30  NTKHLASGSMDSTLMIWHMKSQSRAYRFTGHKDAVTCVNFSPSGHLLASGSRDKTVRIWV 89
           + +   SG+ D++  +W ++       F+GH+  +  + + P+GH  A+GS D T R++ 
Sbjct: 426 DMRTFVSGACDASAKLWDVRDGMCKQTFSGHESDINAITYFPNGHAFATGSDDATCRLFD 247

Query: 90  PNVKGESTVFRAHT--ATVRSVHFCSDGQSLVTASDDKTVKVWSTHRQRFLFSLTQHINW 147
                E  ++        + SV F   G+ L+   DD    +W   +Q     L  H N 
Sbjct: 246 IRADQEIGMYSHDNIICGITSVAFSKSGRLLLGGYDDFNCNIWDVLKQERTGVLAGHDNR 67

Query: 148 VRCAKFSPDGRLIVSAS 164
           V C   + DG  + + S
Sbjct: 66  VSCLGVTEDGSAVATGS 16

 Score = 57.4 bits (137), Expect = 9e-09,   Method: Compositional matrix adjust.
 Identities = 34/142 (23%), Positives = 61/142 (42%), Gaps = 2/142 (1%)
 Frame = -1

Query: 153 FSPDGRLIVSASDDKTVKLWDKTSRECIHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVK 212
            +PD R  VS + D + KLWD     C  ++  H   +  + + P+G   A    D T +
Sbjct: 435 LAPDMRTFVSGACDASAKLWDVRDGMCKQTFSGHESDINAITYFPNGHAFATGSDDATCR 256

Query: 213 VWDARTHRLLQHYQLHS--AAVNALSFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGH 270
           ++D R  + +  Y   +    + +++F  SG  L+    D    I D+++      L GH
Sbjct: 255 LFDIRADQEIGMYSHDNIICGITSVAFSKSGRLLLGGYDDFNCNIWDVLKQERTGVLAGH 76

Query: 271 QGPATTVAFSRTGEYFASGGSD 292
               + +  +  G   A+G  D
Sbjct: 75  DNRVSCLGVTEDGSAVATGSWD 10

 Score = 53.1 bits (126), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 30/104 (28%), Positives = 52/104 (50%), Gaps = 3/104 (2%)
 Frame = -1

Query: 198 SGTCIAAAGMDNTVKVWDARTHRLLQHYQLHSAAVNALSFHPSGNYLITASSDSTLKILD 257
           SG C A+A      K+WD R     Q +  H + +NA+++ P+G+   T S D+T ++ D
Sbjct: 408 SGACDASA------KLWDVRDGMCKQTFSGHESDINAITYFPNGHAFATGSDDATCRLFD 247

Query: 258 LMEGRLLYTLHGHQG---PATTVAFSRTGEYFASGGSDEQVMVW 298
           +   + +  ++ H       T+VAFS++G     G  D    +W
Sbjct: 246 IRADQEI-GMYSHDNIICGITSVAFSKSGRLLLGGYDDFNCNIW 118

 Score = 41.6 bits (96), Expect = 6e-04,   Method: Compositional matrix adjust.
 Identities = 34/143 (23%), Positives = 57/143 (39%), Gaps = 3/143 (2%)
 Frame = -1

Query: 114 DGQSLVTASDDKTVKVWSTHRQRFLFSLTQHINWVRCAKFSPDGRLIVSASDDKTVKLWD 173
           D ++ V+ + D + K+W         + + H + +    + P+G    + SDD T +L+D
Sbjct: 426 DMRTFVSGACDASAKLWDVRDGMCKQTFSGHESDINAITYFPNGHAFATGSDDATCRLFD 247

Query: 174 KTSRECIHSYCEHGGF---VTYVDFHPSGTCIAAAGMDNTVKVWDARTHRLLQHYQLHSA 230
             + + I  Y  H      +T V F  SG  +     D    +WD            H  
Sbjct: 246 IRADQEIGMY-SHDNIICGITSVAFSKSGRLLLGGYDDFNCNIWDVLKQERTGVLAGHDN 70

Query: 231 AVNALSFHPSGNYLITASSDSTL 253
            V+ L     G+ + T S DS L
Sbjct: 69  RVSCLGVTEDGSAVATGSWDSFL 1

 Score = 37.7 bits (86), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 20/62 (32%), Positives = 30/62 (48%)
 Frame = -1

Query: 21  AVTCVDFSLNTKHLASGSMDSTLMIWHMKSQSRAYRFTGHKDAVTCVNFSPSGHLLASGS 80
            +T V FS + + L  G  D    IW +  Q R     GH + V+C+  +  G  +A+GS
Sbjct: 195 GITSVAFSKSGRLLLGGYDDFNCNIWDVLKQERTGVLAGHDNRVSCLGVTEDGSAVATGS 16

Query: 81  RD 82
            D
Sbjct: 15  WD 10
>13278
          Length = 870

 Score = 61.6 bits (148), Expect = 6e-10,   Method: Compositional matrix adjust.
 Identities = 37/100 (37%), Positives = 54/100 (54%)
 Frame = +1

Query: 118 LVTASDDKTVKVWSTHRQRFLFSLTQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKTSR 177
           L +AS D TV++W   R   L +LT+H   V    FSPDG+ + S S DK V +W+  + 
Sbjct: 121 LASASFDSTVRLWEVERGLCLHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNVQTG 300

Query: 178 ECIHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDAR 217
             +HSY   GG +  V ++  G  + A+  D +V V D R
Sbjct: 301 SLVHSYKGTGG-IFEVCWNHRGDKVGASASDGSVFVLDLR 417

 Score = 57.8 bits (138), Expect = 8e-09,   Method: Compositional matrix adjust.
 Identities = 36/139 (25%), Positives = 67/139 (48%), Gaps = 9/139 (6%)
 Frame = +1

Query: 129 VWSTHRQRFLFSLTQHINWVRCAKFSPDG---------RLIVSASDDKTVKLWDKTSREC 179
           +WS  +   +  L      +   K+SP G          ++ SAS D TV+LW+     C
Sbjct: 1   IWSMGKDSCIHDLQLTTKEIYTIKWSPTGPGTSNPNTSLILASASFDSTVRLWEVERGLC 180

Query: 180 IHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDARTHRLLQHYQLHSAAVNALSFHP 239
           +H+  +H   V  V F P G  +A+   D  V +W+ +T  L+  Y+  +  +  + ++ 
Sbjct: 181 LHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNVQTGSLVHSYK-GTGGIFEVCWNH 357

Query: 240 SGNYLITASSDSTLKILDL 258
            G+ +  ++SD ++ +LDL
Sbjct: 358 RGDKVGASASDGSVFVLDL 414

 Score = 53.1 bits (126), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 30/96 (31%), Positives = 48/96 (50%), Gaps = 9/96 (9%)
 Frame = +1

Query: 213 VWDARTHRLLQHYQLHSAAVNALSFHPSGN---------YLITASSDSTLKILDLMEGRL 263
           +W       +   QL +  +  + + P+G           L +AS DST+++ ++  G  
Sbjct: 1   IWSMGKDSCIHDLQLTTKEIYTIKWSPTGPGTSNPNTSLILASASFDSTVRLWEVERGLC 180

Query: 264 LYTLHGHQGPATTVAFSRTGEYFASGGSDEQVMVWK 299
           L+TL  HQ P  +VAFS  G+Y ASG  D+ V +W 
Sbjct: 181 LHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWN 288

 Score = 51.2 bits (121), Expect = 8e-07,   Method: Compositional matrix adjust.
 Identities = 30/75 (40%), Positives = 39/75 (52%), Gaps = 7/75 (9%)
 Frame = +1

Query: 34  LASGSMDSTLMIWHMKSQSRAYRFTGHKDAVTCVNFSPSGHLLASGSRDKTVRIW----- 88
           LAS S DST+ +W ++     +  T H++ V  V FSP G  LASGS DK V IW     
Sbjct: 121 LASASFDSTVRLWEVERGLCLHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNVQTG 300

Query: 89  --VPNVKGESTVFRA 101
             V + KG   +F  
Sbjct: 301 SLVHSYKGTGGIFEV 345

 Score = 49.7 bits (117), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 33/136 (24%), Positives = 58/136 (42%), Gaps = 9/136 (6%)
 Frame = +1

Query: 171 LWDKTSRECIHSYCEHGGFVTYVDFHPSG---------TCIAAAGMDNTVKVWDARTHRL 221
           +W      CIH        +  + + P+G           +A+A  D+TV++W+      
Sbjct: 1   IWSMGKDSCIHDLQLTTKEIYTIKWSPTGPGTSNPNTSLILASASFDSTVRLWEVERGLC 180

Query: 222 LQHYQLHSAAVNALSFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSR 281
           L     H   V +++F P G YL + S D  + I ++  G L+++  G  G    V ++ 
Sbjct: 181 LHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNVQTGSLVHSYKG-TGGIFEVCWNH 357

Query: 282 TGEYFASGGSDEQVMV 297
            G+   +  SD  V V
Sbjct: 358 RGDKVGASASDGSVFV 405

 Score = 40.4 bits (93), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 30/105 (28%), Positives = 42/105 (40%), Gaps = 9/105 (8%)
 Frame = +1

Query: 45  IWHMKSQSRAYRFTGHKDAVTCVNFSPSGH---------LLASGSRDKTVRIWVPNVKGE 95
           IW M   S  +        +  + +SP+G          +LAS S D TVR+W       
Sbjct: 1   IWSMGKDSCIHDLQLTTKEIYTIKWSPTGPGTSNPNTSLILASASFDSTVRLWEVERGLC 180

Query: 96  STVFRAHTATVRSVHFCSDGQSLVTASDDKTVKVWSTHRQRFLFS 140
                 H   V SV F  DG+ L + S DK V +W+      + S
Sbjct: 181 LHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNVQTGSLVHS 315

 Score = 35.8 bits (81), Expect = 0.033,   Method: Compositional matrix adjust.
 Identities = 16/42 (38%), Positives = 27/42 (64%)
 Frame = +1

Query: 18  HRDAVTCVDFSLNTKHLASGSMDSTLMIWHMKSQSRAYRFTG 59
           H++ V  V FS + K+LASGS D  + IW++++ S  + + G
Sbjct: 199 HQEPVYSVAFSPDGKYLASGSFDKCVHIWNVQTGSLVHSYKG 324
>03395
          Length = 2795

 Score = 60.8 bits (146), Expect = 8e-10,   Method: Compositional matrix adjust.
 Identities = 40/154 (25%), Positives = 70/154 (45%), Gaps = 9/154 (5%)
 Frame = +2

Query: 157 GRLIVSASDDKTVKLWD--------KTSRECIHSYCEHGGFVTYVDFHPSGTCIAAAGMD 208
           G  +VS   +  V++WD        KT  + + +  EH G VT +  H +  C  +A  D
Sbjct: 32  GTKLVSGGGEGQVRVWDIVKDMLTGKTRGDLVANMKEHKGKVTAIQIHTNDRCCVSASTD 211

Query: 209 NTVKVWDARTHRLLQHYQLHSAAVNALSFHPSGNYLITASSDSTLKILDLMEGRLLYTLH 268
            +  +WD  T+   Q   L +     + F     +++T+ +D  +   ++ +G LL  L 
Sbjct: 212 GSTIIWDLITNTRSQ-IVLANTLFKCVCFGGKDLHILTSGTDHKIGYWEVGDGGLLRELE 388

Query: 269 GHQ-GPATTVAFSRTGEYFASGGSDEQVMVWKSN 301
           G Q G   T+   R G+   +GG D  + +W+ N
Sbjct: 389 GSQTGAINTIDIDRDGQTILTGGEDSLLKLWRYN 490

 Score = 60.5 bits (145), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 49/206 (23%), Positives = 81/206 (39%), Gaps = 12/206 (5%)
 Frame = +2

Query: 106 VRSVHFCSDGQSLVTASDDKTVKVW--------STHRQRFLFSLTQHINWVRCAKFSPDG 157
           V ++   S G  LV+   +  V+VW           R   + ++ +H   V   +   + 
Sbjct: 5   VTAIAVTSCGTKLVSGGGEGQVRVWDIVKDMLTGKTRGDLVANMKEHKGKVTAIQIHTND 184

Query: 158 RLIVSASDDKTVKLWD---KTSRECIHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVW 214
           R  VSAS D +  +WD    T  + + +          V F      I  +G D+ +  W
Sbjct: 185 RCCVSASTDGSTIIWDLITNTRSQIVLANT----LFKCVCFGGKDLHILTSGTDHKIGYW 352

Query: 215 DARTHRLLQHYQ-LHSAAVNALSFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGHQGP 273
           +     LL+  +   + A+N +     G  ++T   DS LK+    EG + +T  GH   
Sbjct: 353 EVGDGGLLRELEGSQTGAINTIDIDRDGQTILTGGEDSLLKLWRYNEGEVTHTGIGHSNQ 532

Query: 274 ATTVAFSRTGEYFASGGSDEQVMVWK 299
            T         Y  SGG D  + +WK
Sbjct: 533 ITKARICPNRHYIVSGGEDGALHIWK 610

 Score = 58.9 bits (141), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 40/167 (23%), Positives = 74/167 (44%), Gaps = 5/167 (2%)
 Frame = +2

Query: 11  LERHFKGHRDAVTCVDFSLNTKHLASGSMDSTLMIWHMKSQSRAYRFTGHKDAVTCVNFS 70
           L  + K H+  VT +    N +   S S D + +IW + + +R+     +     CV F 
Sbjct: 122 LVANMKEHKGKVTAIQIHTNDRCCVSASTDGSTIIWDLITNTRSQIVLANT-LFKCVCFG 298

Query: 71  PSG-HLLASGSRDKTVRIWVPNVKGESTVFR----AHTATVRSVHFCSDGQSLVTASDDK 125
               H+L SG+ D  +  W     G+  + R    + T  + ++    DGQ+++T  +D 
Sbjct: 299 GKDLHILTSGT-DHKIGYWEV---GDGGLLRELEGSQTGAINTIDIDRDGQTILTGGEDS 466

Query: 126 TVKVWSTHRQRFLFSLTQHINWVRCAKFSPDGRLIVSASDDKTVKLW 172
            +K+W  +      +   H N +  A+  P+   IVS  +D  + +W
Sbjct: 467 LLKLWRYNEGEVTHTGIGHSNQITKARICPNRHYIVSGGEDGALHIW 607
>26939
          Length = 388

 Score = 60.5 bits (145), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 25/61 (40%), Positives = 40/61 (65%)
 Frame = +2

Query: 157 GRLIVSASDDKTVKLWDKTSRECIHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDA 216
           G+ +VSASDDKT+++WD  ++ C+ +   H  F T +DFH +   + +  +D TVKVW+ 
Sbjct: 2   GKYLVSASDDKTIRVWDLRNKRCMKTLYAHQHFCTSIDFHKAHPYVISGSVDQTVKVWEC 181

Query: 217 R 217
           R
Sbjct: 182 R 184

 Score = 53.5 bits (127), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 23/59 (38%), Positives = 35/59 (59%)
 Frame = +2

Query: 241 GNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGEYFASGGSDEQVMVWK 299
           G YL++AS D T+++ DL   R + TL+ HQ   T++ F +   Y  SG  D+ V VW+
Sbjct: 2   GKYLVSASDDKTIRVWDLRNKRCMKTLYAHQHFCTSIDFHKAHPYVISGSVDQTVKVWE 178

 Score = 45.8 bits (107), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 22/59 (37%), Positives = 36/59 (61%)
 Frame = +2

Query: 115 GQSLVTASDDKTVKVWSTHRQRFLFSLTQHINWVRCAKFSPDGRLIVSASDDKTVKLWD 173
           G+ LV+ASDDKT++VW    +R + +L  H ++     F      ++S S D+TVK+W+
Sbjct: 2   GKYLVSASDDKTIRVWDLRNKRCMKTLYAHQHFCTSIDFHKAHPYVISGSVDQTVKVWE 178

 Score = 42.0 bits (97), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 18/57 (31%), Positives = 31/57 (54%)
 Frame = +2

Query: 199 GTCIAAAGMDNTVKVWDARTHRLLQHYQLHSAAVNALSFHPSGNYLITASSDSTLKI 255
           G  + +A  D T++VWD R  R ++    H     ++ FH +  Y+I+ S D T+K+
Sbjct: 2   GKYLVSASDDKTIRVWDLRNKRCMKTLYAHQHFCTSIDFHKAHPYVISGSVDQTVKV 172

 Score = 38.5 bits (88), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 17/57 (29%), Positives = 32/57 (56%)
 Frame = +2

Query: 32 KHLASGSMDSTLMIWHMKSQSRAYRFTGHKDAVTCVNFSPSGHLLASGSRDKTVRIW 88
          K+L S S D T+ +W ++++        H+   T ++F  +   + SGS D+TV++W
Sbjct: 5  KYLVSASDDKTIRVWDLRNKRCMKTLYAHQHFCTSIDFHKAHPYVISGSVDQTVKVW 175

 Score = 36.2 bits (82), Expect = 0.022,   Method: Compositional matrix adjust.
 Identities = 21/58 (36%), Positives = 28/58 (48%)
 Frame = +2

Query: 73  GHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSLVTASDDKTVKVW 130
           G  L S S DKT+R+W    K       AH     S+ F      +++ S D+TVKVW
Sbjct: 2   GKYLVSASDDKTIRVWDLRNKRCMKTLYAHQHFCTSIDFHKAHPYVISGSVDQTVKVW 175
>24785
          Length = 455

 Score = 60.5 bits (145), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 27/49 (55%), Positives = 39/49 (79%)
 Frame = +1

Query: 357 LTSTLEHIVGQLDILTQTVSILEQRLTLTEDRLKQCLENQQLIMQRTPP 405
           ++  +E I GQLDILTQTVS+LEQRLT+TE++L++C++ QQ I  +  P
Sbjct: 79  MSKFMEQIAGQLDILTQTVSLLEQRLTMTENKLRECMDGQQEIRLQIKP 225
>01805
          Length = 2124

 Score = 59.7 bits (143), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 48/173 (27%), Positives = 82/173 (47%), Gaps = 6/173 (3%)
 Frame = -1

Query: 17  GHRDAVTCVDFSLNTKH-LASGSMDSTLMIWHMKSQSRAYRFTGHKDAVTCVNFSP-SGH 74
           GH  AV  + ++ N +H LAS S D+T+ +W +     A  FT H   V C N+ P    
Sbjct: 582 GHTQAVLDLSWNRNARHVLASASADTTVALWDLSEGKMAMNFTQHSREVQCCNWHPQEEQ 403

Query: 75  LLASGSRDKTVRIWVPNVKGESTVFRAHTA---TVRSVHFCSDGQSLVTASDDKTVKVWS 131
            L +GS D TV+  V + +   T  ++ T      ++V    +   L+  +D   V  + 
Sbjct: 402 TLLTGSFDNTVK--VVDCRSAETCHKSWTVEGEVEKAVWNHHNPLQLLACTDKGMVYCFD 229

Query: 132 THRQRFLFSLTQHINWVRCAKFSPD-GRLIVSASDDKTVKLWDKTSRECIHSY 183
              ++ +FS+  H + V     S     L+++ S+DKT+K+WD    +  H +
Sbjct: 228 IRHEKPVFSVGAHSSCVTGVCLSSQIPGLMITTSEDKTMKVWDIQDDKPTHVF 70

 Score = 41.6 bits (96), Expect = 6e-04,   Method: Compositional matrix adjust.
 Identities = 25/98 (25%), Positives = 45/98 (45%), Gaps = 12/98 (12%)
 Frame = -1

Query: 202 IAAAGMDNTVKVWDARTHRLLQHYQLHSAAVNALSFHPSGNY-LITASSDSTLKILDL-- 258
           +A+A  D TV +WD    ++  ++  HS  V   ++HP     L+T S D+T+K++D   
Sbjct: 528 LASASADTTVALWDLSEGKMAMNFTQHSREVQCCNWHPQEEQTLLTGSFDNTVKVVDCRS 349

Query: 259 ---------MEGRLLYTLHGHQGPATTVAFSRTGEYFA 287
                    +EG +   +  H  P   +A +  G  + 
Sbjct: 348 AETCHKSWTVEGEVEKAVWNHHNPLQLLACTDKGMVYC 235
>31474
          Length = 403

 Score = 58.2 bits (139), Expect = 5e-09,   Method: Compositional matrix adjust.
 Identities = 34/109 (31%), Positives = 55/109 (50%), Gaps = 5/109 (4%)
 Frame = -3

Query: 179 CIHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDARTHRLLQHYQL---HSAAVNAL 235
           C+ ++ EH   V +   +P+GT +A+ G D  +K+W       +    L   H+  V +L
Sbjct: 320 CLSAHDEHAWCVAW---NPTGTLLASCGSDKIIKIWGKEGDNWVCKSTLTDAHTRTVRSL 150

Query: 236 SFHPSGNYLITASSDSTLKILDLMEGRL--LYTLHGHQGPATTVAFSRT 282
            + P GNYL +AS D+T  +     G    + TL GH+     VA++RT
Sbjct: 149 GWSPCGNYLSSASFDATTAVWSRKGGEFECIATLEGHENEVKAVAWART 3

 Score = 55.1 bits (131), Expect = 5e-08,   Method: Compositional matrix adjust.
 Identities = 37/103 (35%), Positives = 54/103 (52%), Gaps = 5/103 (4%)
 Frame = -3

Query: 57  FTGHKDAVTCVNFSPSGHLLASGSRDKTVRIWVP---NVKGESTVFRAHTATVRSVHFCS 113
            + H +   CV ++P+G LLAS   DK ++IW     N   +ST+  AHT TVRS+ +  
Sbjct: 317 LSAHDEHAWCVAWNPTGTLLASCGSDKIIKIWGKEGDNWVCKSTLTDAHTRTVRSLGWSP 138

Query: 114 DGQSLVTASDDKTVKVWSTHRQRF--LFSLTQHINWVRCAKFS 154
            G  L +AS D T  VWS     F  + +L  H N V+   ++
Sbjct: 137 CGNYLSSASFDATTAVWSRKGGEFECIATLEGHENEVKAVAWA 9

 Score = 35.0 bits (79), Expect = 0.051,   Method: Compositional matrix adjust.
 Identities = 26/91 (28%), Positives = 36/91 (39%), Gaps = 5/91 (5%)
 Frame = -3

Query: 95  ESTVFRAHTATVRSVHFCSDGQSLVTASDDKTVKVWSTHRQRFLFSLT---QHINWVRCA 151
           E     AH      V +   G  L +   DK +K+W      ++   T    H   VR  
Sbjct: 329 EVCCLSAHDEHAWCVAWNPTGTLLASCGSDKIIKIWGKEGDNWVCKSTLTDAHTRTVRSL 150

Query: 152 KFSPDGRLIVSASDDKTVKLWDKTSR--ECI 180
            +SP G  + SAS D T  +W +     ECI
Sbjct: 149 GWSPCGNYLSSASFDATTAVWSRKGGEFECI 57

 Score = 27.7 bits (60), Expect = 8.1,   Method: Compositional matrix adjust.
 Identities = 14/37 (37%), Positives = 19/37 (51%)
 Frame = -3

Query: 267 LHGHQGPATTVAFSRTGEYFASGGSDEQVMVWKSNFD 303
           L  H   A  VA++ TG   AS GSD+ + +W    D
Sbjct: 317 LSAHDEHAWCVAWNPTGTLLASCGSDKIIKIWGKEGD 207
>02960
          Length = 1577

 Score = 57.8 bits (138), Expect = 7e-09,   Method: Compositional matrix adjust.
 Identities = 73/303 (24%), Positives = 124/303 (40%), Gaps = 41/303 (13%)
 Frame = +2

Query: 36  SGSMDSTLMIWHMKSQSRAYRFTGHKDAVTCVNF-----SPSGHLLASGSRDKTVRIW-- 88
           SGS D+T+ +W  K ++      GH   V CV +     S       +GS D+T  +W  
Sbjct: 530 SGSYDNTVRLWSTKGEA-IMTIPGHTSPVKCVAWIKHDESSGVSTFVTGSHDQTALVWQW 706

Query: 89  --VPNVKGESTVFRAHTATVRSVHFCSDGQSLVTASDDKTVKVWS--------------- 131
               N        R H A+V  V    D Q + T S DK +K+WS               
Sbjct: 707 QRETNEVDCRLSCRGHAASVDCVAVSPDSQQMCTGSWDKMLKLWSTDCNVDGDQSEDTER 886

Query: 132 -----------THRQRFLFSLTQHINWVRCAKFSPDGRLIVSASDDKTVKLWD-KTSREC 179
                      T  +  + +L+ H   V   ++  D   +V++S D +++LWD  T+++ 
Sbjct: 887 PSKKKKSAKSTTQTRVPVLTLSGHAEAVSAVRW-LDPHRVVTSSWDHSLRLWDLHTAQQT 1063

Query: 180 IHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDARTHR---LLQHYQLHSAAVNALS 236
             S  +    V  V + P    +     D  V++ D R      +   +  H+  V  + 
Sbjct: 1064--SLIQGSKAVLDVAYSPLSHMLITGSADRHVRLVDPRCSEGETVKCAFTSHTGWVTGVD 1237

Query: 237 FHPSGNYL-ITASSDSTLKILDLMEGRL-LYTLHGHQGPATTVAFSRTGEYFASGGSDEQ 294
           + P+  +L ++ S D+ LK+ D    +  LY ++ H+     V +S   E   SGG D +
Sbjct: 1238WSPTREHLFLSGSYDNVLKLWDTRSPKATLYDMNWHEDRILAVDWS-IPELLLSGGVDNK 1414

Query: 295 VMV 297
           + V
Sbjct: 1415LHV 1423
>15118
          Length = 1074

 Score = 57.4 bits (137), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 44/161 (27%), Positives = 76/161 (47%), Gaps = 4/161 (2%)
 Frame = +3

Query: 144 HINWVRCAKFSPDGRLIVSASDDKTVKLWDKTSRE---CIHSYCEHGGFVTYVDFHPSGT 200
           H++ VR   F     L+++A  D  +K W   SR+    +    +    ++ +  H    
Sbjct: 189 HVSGVRGVAFDAFNCLLITAGGDCDIKFWRFGSRDRARVLLKELKMSEGISRILLHRDSN 368

Query: 201 CIAAAGMDNTVKVWDARTHRLLQHYQLHSAAVNALSFHPSGNYLITASSDSTLKILDLME 260
            +A    D TV V D  T R+++ +  HS ++  LSF   G +LITAS D T++   L+ 
Sbjct: 369 MLAVVLEDFTVSVIDVDTLRVVRVFSGHSNSITDLSFSGDGRWLITASMDCTVRTWSLVH 548

Query: 261 GRLLYTLHGHQGPATTVAFSRTGEYFA-SGGSDEQVMVWKS 300
           GRL+      +   T++  S + ++ A S   D  V +W +
Sbjct: 549 GRLIDCF-AVEAAVTSLTMSPSQDFLATSHVGDVGVYLWAN 668

 Score = 37.4 bits (85), Expect = 0.010,   Method: Compositional matrix adjust.
 Identities = 31/124 (25%), Positives = 51/124 (41%), Gaps = 3/124 (2%)
 Frame = +3

Query: 18  HRDAVTCVDFSLNTKHLASGSMDSTLMIWHMKSQSRA---YRFTGHKDAVTCVNFSPSGH 74
           H   V  V F      L +   D  +  W   S+ RA    +     + ++ +      +
Sbjct: 189 HVSGVRGVAFDAFNCLLITAGGDCDIKFWRFGSRDRARVLLKELKMSEGISRILLHRDSN 368

Query: 75  LLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSLVTASDDKTVKVWSTHR 134
           +LA    D TV +   +      VF  H+ ++  + F  DG+ L+TAS D TV+ WS   
Sbjct: 369 MLAVVLEDFTVSVIDVDTLRVVRVFSGHSNSITDLSFSGDGRWLITASMDCTVRTWSLVH 548

Query: 135 QRFL 138
            R +
Sbjct: 549 GRLI 560

 Score = 34.7 bits (78), Expect = 0.068,   Method: Compositional matrix adjust.
 Identities = 26/77 (33%), Positives = 38/77 (49%), Gaps = 1/77 (1%)
 Frame = +3

Query: 13  RHFKGHRDAVTCVDFSLNTKHLASGSMDSTLMIWHMKSQSRAYRFTGHKDAVTCVNFSPS 72
           R F GH +++T + FS + + L + SMD T+  W +    R       + AVT +  SPS
Sbjct: 435 RVFSGHSNSITDLSFSGDGRWLITASMDCTVRTWSLV-HGRLIDCFAVEAAVTSLTMSPS 611

Query: 73  GHLLA-SGSRDKTVRIW 88
              LA S   D  V +W
Sbjct: 612 QDFLATSHVGDVGVYLW 662
>14555
          Length = 627

 Score = 40.0 bits (92), Expect(2) = 3e-08,   Method: Compositional matrix adjust.
 Identities = 17/47 (36%), Positives = 24/47 (51%)
 Frame = -2

Query: 57  FTGHKDAVTCVNFSPSGHLLASGSRDKTVRIWVPNVKGESTVFRAHT 103
           F GH+  + CV F PSG   A+GS D T R++      E   +R  +
Sbjct: 611 FEGHEADINCVRFYPSGDAFATGSDDATCRLFDLRADREVNCYRKES 471

 Score = 35.8 bits (81), Expect(2) = 3e-08,   Method: Compositional matrix adjust.
 Identities = 18/52 (34%), Positives = 27/52 (51%)
 Frame = -3

Query: 121 ASDDKTVKVWSTHRQRFLFSLTQHINWVRCAKFSPDGRLIVSASDDKTVKLW 172
            ++D TV VW   +      L  H N V C + SPDG  + + S D T+++W
Sbjct: 412 VTNDYTVNVWDALKGMRSTILYGHDNRVSCLRISPDGTSLCTGSWDYTLRIW 257

 Score = 41.6 bits (96), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 19/49 (38%), Positives = 27/49 (55%)
 Frame = -3

Query: 40  DSTLMIWHMKSQSRAYRFTGHKDAVTCVNFSPSGHLLASGSRDKTVRIW 88
           D T+ +W      R+    GH + V+C+  SP G  L +GS D T+RIW
Sbjct: 403 DYTVNVWDALKGMRSTILYGHDNRVSCLRISPDGTSLCTGSWDYTLRIW 257

 Score = 38.9 bits (89), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 22/70 (31%), Positives = 32/70 (45%), Gaps = 2/70 (2%)
 Frame = -2

Query: 178 ECIHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDARTHRLLQHYQLHSA--AVNAL 235
           EC+  +  H   +  V F+PSG   A    D T +++D R  R +  Y+  S     NA+
Sbjct: 626 ECVQMFEGHEADINCVRFYPSGDAFATGSDDATCRLFDLRADREVNCYRKESIIFGCNAV 447

Query: 236 SFHPSGNYLI 245
            F  SG  L 
Sbjct: 446 DFSVSGRLLF 417

 Score = 36.2 bits (82), Expect = 0.027,   Method: Compositional matrix adjust.
 Identities = 21/67 (31%), Positives = 33/67 (49%), Gaps = 2/67 (2%)
 Frame = -2

Query: 15  FKGHRDAVTCVDFSLNTKHLASGSMDSTLMIWHMKS--QSRAYRFTGHKDAVTCVNFSPS 72
           F+GH   + CV F  +    A+GS D+T  ++ +++  +   YR          V+FS S
Sbjct: 611 FEGHEADINCVRFYPSGDAFATGSDDATCRLFDLRADREVNCYRKESIIFGCNAVDFSVS 432

Query: 73  GHLLASG 79
           G LL  G
Sbjct: 431 GRLLFGG 411

 Score = 29.6 bits (65), Expect = 2.1,   Method: Compositional matrix adjust.
 Identities = 12/32 (37%), Positives = 18/32 (56%), Gaps = 1/32 (3%)
 Frame = -2

Query: 148 VRCAKFSPDGRLIVSASDDKTVKLWD-KTSRE 178
           + C +F P G    + SDD T +L+D +  RE
Sbjct: 590 INCVRFYPSGDAFATGSDDATCRLFDLRADRE 495

 Score = 28.1 bits (61), Expect = 5.8,   Method: Compositional matrix adjust.
 Identities = 13/32 (40%), Positives = 18/32 (56%)
 Frame = -3

Query: 15  FKGHRDAVTCVDFSLNTKHLASGSMDSTLMIW 46
             GH + V+C+  S +   L +GS D TL IW
Sbjct: 352 LYGHDNRVSCLRISPDGTSLCTGSWDYTLRIW 257

 Score = 28.1 bits (61), Expect = 7.2,   Method: Compositional matrix adjust.
 Identities = 15/70 (21%), Positives = 29/70 (41%)
 Frame = -3

Query: 229 SAAVNALSFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGEYFAS 288
           S A     F    +  +  ++D T+ + D ++G     L+GH    + +  S  G    +
Sbjct: 466 SLAATLWIFLSVVDCCLGVTNDYTVNVWDALKGMRSTILYGHDNRVSCLRISPDGTSLCT 287

Query: 289 GGSDEQVMVW 298
           G  D  + +W
Sbjct: 286 GSWDYTLRIW 257
>01598
          Length = 1545

 Score = 55.1 bits (131), Expect = 5e-08,   Method: Compositional matrix adjust.
 Identities = 60/267 (22%), Positives = 113/267 (42%), Gaps = 28/267 (10%)
 Frame = +1

Query: 73  GHLLASGSRDKTVRIW------------VPNVKGESTVFRAHTATVRSVHFC-SDGQSLV 119
           G L+A+GS+D+T+R+W            +PN + E+    +      ++H+  S+ + LV
Sbjct: 100 GCLIATGSKDRTIRVWTLSQGKQIFMKKLPNQRREAGDTGSRFKVWLAIHWLKSNPEQLV 279

Query: 120 TASDDKTVKVWS---THRQRF-LFSLTQHINWVR-----CAKFSPDGRLIVSASDDKTVK 170
           ++S    + +WS   T  Q +  F  + +   +R     CA   PD + + + + D+ V 
Sbjct: 280 SSSSGGDLLLWSLRYTKGQAYQTFQTSDYRPHMRPVFNICAS-GPDSKTLCTFAQDRQVV 456

Query: 171 LWDKTSRECIHSYCEHGGFVTYVDFHPSGTCIAAAGM-DNTVKVWD----ARTHRLLQHY 225
           LWD  + E + S    GG V  V   P      A G+ D+ ++ W+       + +   +
Sbjct: 457 LWDLETMEAVASMATLGGHVYCVRTSPIDPGRVAVGVGDSMIRTWNMSNKTNPYDVTTLW 636

Query: 226 QLHSAAVNALSFHPSG-NYLITASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGE 284
           Q   + V A+++HP+   +L   + D  + + D++          H+ P  +  F     
Sbjct: 637 QGIKSKVTAVAWHPTKEGWLGFGTDDGRIGVFDVLS---------HKMPTLSNTFHHRTA 789

Query: 285 YFASGGSDEQVMVWKSNFDIVDYGDMK 311
           Y    G          +F +   GD K
Sbjct: 790 YVVCWGPASLSPTDGKSFSLYSVGDCK 870

 Score = 47.8 bits (112), Expect = 8e-06,   Method: Compositional matrix adjust.
 Identities = 78/337 (23%), Positives = 130/337 (38%), Gaps = 59/337 (17%)
 Frame = +1

Query: 22  VTCVDFS-LNTKHLASGSMDSTLMIWHMKSQSRAYRFT----GHKDAVTCVNFSPSGH-L 75
           V CV  S ++   +A G  DS +  W+M +++  Y  T    G K  VT V + P+    
Sbjct: 514 VYCVRTSPIDPGRVAVGVGDSMIRTWNMSNKTNPYDVTTLWQGIKSKVTAVAWHPTKEGW 693

Query: 76  LASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSLVTASDDKTVKVWSTHRQ 135
           L  G+ D   RI V +V        ++T   R+ +    G + ++ +D K+  ++S    
Sbjct: 694 LGFGTDDG--RIGVFDVLSHKMPTLSNTFHHRTAYVVCWGPASLSPTDGKSFSLYSVGDC 867

Query: 136 RFL----------------FSLTQHINWVRCAK----------FSPDGRLIVSASDDKTV 169
           + L                  +TQ I  V   +          +SPD       +D+ +V
Sbjct: 868 KILEHSSAVLSRGEKKANAIDITQKIGAVNSDQVKGLKATELSWSPDQNAAAVGTDEGSV 1047

Query: 170 KLWDKTSRECIHSYCEHGGFVTYVDFHP---------SGTC--IAAAGMDNTVKV----- 213
            +      + + +       +  V +HP         S  C  +AAAG D  + V     
Sbjct: 1048YVVTIQDLKIVAAIRTQQKLINCVRWHPRLTDQSPAGSPCCHWLAAAGNDQVIHVVDLAS 1227

Query: 214 ------WDARTHRLL---QHYQLHSAAVNALSFHPSGNY-LITASSDSTLKILDLMEGRL 263
                  D  T  +L   +    HS  V  +S+ P  +  L++   D+   + D+ +G  
Sbjct: 1228VFAEREGDKETSLILTSLRELSGHSQRVTDMSWSPHHDARLVSVGYDAEAFVWDVQKGTA 1407

Query: 264 LYTLHGHQGPATTVAFSRTG-EYFASGGSDEQVMVWK 299
           L    GH G   T  FS    +   +GGSD  V VW+
Sbjct: 1408LAQFKGHMGRLLTCQFSGLDPDLVMTGGSDASVHVWR 1518

 Score = 31.2 bits (69), Expect = 0.85,   Method: Compositional matrix adjust.
 Identities = 22/80 (27%), Positives = 34/80 (42%), Gaps = 4/80 (5%)
 Frame = +1

Query: 13   RHFKGHRDAVTCVDFSLNTKH---LASGSMDSTLMIWHMKSQSRAYRFTGHKDAVTCVNF 69
            R   GH   VT  D S +  H   L S   D+   +W ++  +   +F GH   +    F
Sbjct: 1282 RELSGHSQRVT--DMSWSPHHDARLVSVGYDAEAFVWDVQKGTALAQFKGHMGRLLTCQF 1455

Query: 70   SP-SGHLLASGSRDKTVRIW 88
            S     L+ +G  D +V +W
Sbjct: 1456 SGLDPDLVMTGGSDASVHVW 1515
>16105
          Length = 960

 Score = 53.5 bits (127), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 51/219 (23%), Positives = 87/219 (39%), Gaps = 6/219 (2%)
 Frame = -2

Query: 89  VPNVKGESTVFRAHTATVRSVHFCSDGQSLV-TASDDKTVKVWSTHRQRFLFSLTQHINW 147
           V  V  ++ +   H   V  + +C    +++ +ASDD TVKVW                 
Sbjct: 617 VGRVPVDNPLVAGHKGAVLDIQWCPHNDNVIASASDDCTVKVWQI--------------- 483

Query: 148 VRCAKFSPDGRLIVSASDDKTVKLWDKTSRECIHSYCEHGGFVTYVDFHPSG-TCIAAAG 206
                  PD  L+ + + D  V L     R C+            + +HPS    + +AG
Sbjct: 482 -------PDSGLVTNLT-DPVVDLVGHQKRCCL------------IVWHPSAQNVLVSAG 363

Query: 207 MDNTVKVWDARTHRLLQHYQLHSAAVNALSFHPSGNYLITASSDSTLKILDLMEGRLLYT 266
            DN +  W+  T   +    +    +  +SF+ +G+ L+    D  L+I+D   G +L  
Sbjct: 362 ADNKILFWNVGTGEPMLEVDVPD-MIYCMSFNFNGSRLVCTCKDKKLRIIDSHSGAVLKE 186

Query: 267 LHGHQGPATTVA-FSRTGEYFASG---GSDEQVMVWKSN 301
              H G     A + + G+ F +G    S+ Q  +W  N
Sbjct: 185 GKCHDGAKPAQACYLKDGKVFTTGFSRMSERQYAIWDEN 69
>21105
          Length = 650

 Score = 52.8 bits (125), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 26/100 (26%), Positives = 51/100 (51%), Gaps = 4/100 (4%)
 Frame = +1

Query: 119 VTASDDKTVKVWSTHRQRFLFSLTQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKTSRE 178
           +TA +D+ ++ +  +  + + ++  H++ V      P+G  ++S S D +++LW+  S+ 
Sbjct: 112 ITAHEDRHIRFFDNNTGKLIHAMVAHLDSVTSLAVDPNGLYLLSGSHDCSIRLWNLDSKT 291

Query: 179 CIHSYCEH----GGFVTYVDFHPSGTCIAAAGMDNTVKVW 214
           C+     H       +  V FHP    IA+AG D   KV+
Sbjct: 292 CVQEITSHRKKFDESIHDVAFHPQKPYIASAGADALAKVF 411

 Score = 47.0 bits (110), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 23/106 (21%), Positives = 56/106 (52%), Gaps = 4/106 (3%)
 Frame = +1

Query: 155 PDGRLIVSASDDKTVKLWDKTSRECIHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVW 214
           P   + ++A +D+ ++ +D  + + IH+   H   VT +   P+G  + +   D ++++W
Sbjct: 94  PTMPITITAHEDRHIRFFDNNTGKLIHAMVAHLDSVTSLAVDPNGLYLLSGSHDCSIRLW 273

Query: 215 --DART--HRLLQHYQLHSAAVNALSFHPSGNYLITASSDSTLKIL 256
             D++T    +  H +    +++ ++FHP   Y+ +A +D+  K+ 
Sbjct: 274 NLDSKTCVQEITSHRKKFDESIHDVAFHPQKPYIASAGADALAKVF 411

 Score = 41.6 bits (96), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 27/107 (25%), Positives = 49/107 (45%), Gaps = 4/107 (3%)
 Frame = +1

Query: 196 HPSGTCIAAAGMDNTVKVWDARTHRLLQHYQLHSAAVNALSFHPSGNYLITASSDSTLKI 255
           HP+      A  D  ++ +D  T +L+     H  +V +L+  P+G YL++ S D ++++
Sbjct: 91  HPTMPITITAHEDRHIRFFDNNTGKLIHAMVAHLDSVTSLAVDPNGLYLLSGSHDCSIRL 270

Query: 256 LDLMEGRLLYTLHGHQGPATT----VAFSRTGEYFASGGSDEQVMVW 298
            +L     +  +  H+         VAF     Y AS G+D    V+
Sbjct: 271 WNLDSKTCVQEITSHRKKFDESIHDVAFHPQKPYIASAGADALAKVF 411

 Score = 37.7 bits (86), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 21/77 (27%), Positives = 39/77 (50%), Gaps = 4/77 (5%)
 Frame = +1

Query: 17  GHRDAVTCVDFSLNTKHLASGSMDSTLMIWHMKSQSRAYRFTGHK----DAVTCVNFSPS 72
            H D+VT +    N  +L SGS D ++ +W++ S++     T H+    +++  V F P 
Sbjct: 184 AHLDSVTSLAVDPNGLYLLSGSHDCSIRLWNLDSKTCVQEITSHRKKFDESIHDVAFHPQ 363

Query: 73  GHLLASGSRDKTVRIWV 89
              +AS   D   +++V
Sbjct: 364 KPYIASAGADALAKVFV 414

 Score = 32.0 bits (71), Expect = 0.52,   Method: Compositional matrix adjust.
 Identities = 22/84 (26%), Positives = 37/84 (44%), Gaps = 4/84 (4%)
 Frame = +1

Query: 55  YRFTGHKDAVTCVNFSPSGHLLASGSRDKTVRIWVPNVKGESTVFRAH----TATVRSVH 110
           +    H D+VT +   P+G  L SGS D ++R+W  + K       +H      ++  V 
Sbjct: 172 HAMVAHLDSVTSLAVDPNGLYLLSGSHDCSIRLWNLDSKTCVQEITSHRKKFDESIHDVA 351

Query: 111 FCSDGQSLVTASDDKTVKVWSTHR 134
           F      + +A  D   KV+  H+
Sbjct: 352 FHPQKPYIASAGADALAKVFV*HQ 423

 Score = 28.9 bits (63), Expect = 3.8,   Method: Compositional matrix adjust.
 Identities = 22/106 (20%), Positives = 44/106 (41%), Gaps = 4/106 (3%)
 Frame = +1

Query: 71  PSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSLVTASDDKTVKVW 130
           P+  +  +   D+ +R +  N         AH  +V S+    +G  L++ S D ++++W
Sbjct: 94  PTMPITITAHEDRHIRFFDNNTGKLIHAMVAHLDSVTSLAVDPNGLYLLSGSHDCSIRLW 273

Query: 131 STHRQRFLFSLTQHINW----VRCAKFSPDGRLIVSASDDKTVKLW 172
           +   +  +  +T H       +    F P    I SA  D   K++
Sbjct: 274 NLDSKTCVQEITSHRKKFDESIHDVAFHPQKPYIASAGADALAKVF 411
>01768
          Length = 1424

 Score = 51.6 bits (122), Expect = 5e-07,   Method: Compositional matrix adjust.
 Identities = 43/149 (28%), Positives = 74/149 (49%), Gaps = 13/149 (8%)
 Frame = +3

Query: 1   MAAPSQEDPSLERH-FKGHRDAVTCVDFSLNTKHL-ASGSMDSTLMIWHMKSQ-SRAYRF 57
           ++ PS    + E+  +  H D+V  V +S N  ++ AS S+D TL IW+ + + S+A   
Sbjct: 780 ISQPSSSGWTTEKSSYAAHTDSVEDVQWSPNEGNVFASCSVDRTLRIWNTQQKPSKANVL 959

Query: 58  T---GHKDAVTCVNFSP-SGHLLASGSRDKTVRIWVPNVKGESTV-----FRAHTATVRS 108
           T    H   +  +N++P   HLLASG  D  ++IW   +     V     F+ H+  V S
Sbjct: 960 TVPEAHSRDINVINWNPIEKHLLASGGDDGIIKIWDLRMFRNKPVSAQASFKLHSQPVTS 1139

Query: 109 VHFCSDGQSLVTAS-DDKTVKVWSTHRQR 136
           + +     S++ AS +D  + +W    +R
Sbjct: 1140LEWNPQDSSVLAASGEDDQITIWDFSVER 1226

 Score = 48.1 bits (113), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 36/141 (25%), Positives = 70/141 (49%), Gaps = 12/141 (8%)
 Frame = +3

Query: 130 WSTHRQRFLFSLTQHINWVRCAKFSP-DGRLIVSASDDKTVKLWD---KTSRECIHSYCE 185
           W+T +  +      H + V   ++SP +G +  S S D+T+++W+   K S+  + +  E
Sbjct: 804 WTTEKSSY----AAHTDSVEDVQWSPNEGNVFASCSVDRTLRIWNTQQKPSKANVLTVPE 971

Query: 186 -HGGFVTYVDFHP-SGTCIAAAGMDNTVKVWDARTHR-----LLQHYQLHSAAVNALSFH 238
            H   +  ++++P     +A+ G D  +K+WD R  R         ++LHS  V +L ++
Sbjct: 972 AHSRDINVINWNPIEKHLLASGGDDGIIKIWDLRMFRNKPVSAQASFKLHSQPVTSLEWN 1151

Query: 239 PSGNYLITAS-SDSTLKILDL 258
           P  + ++ AS  D  + I D 
Sbjct: 1152PQDSSVLAASGEDDQITIWDF 1214
>18981
          Length = 407

 Score = 51.2 bits (121), Expect = 7e-07,   Method: Compositional matrix adjust.
 Identities = 32/109 (29%), Positives = 50/109 (45%)
 Frame = -2

Query: 34  LASGSMDSTLMIWHMKSQSRAYRFTGHKDAVTCVNFSPSGHLLASGSRDKTVRIWVPNVK 93
           + S + D TL +W +K+    +   GH D V CV     G  + SGS DKT+ +W  +  
Sbjct: 379 IISAATDRTLRVWCLKNTCLLHTLRGHNDDVECVCI--YGRRVVSGSWDKTLIVWEVDTG 206

Query: 94  GESTVFRAHTATVRSVHFCSDGQSLVTASDDKTVKVWSTHRQRFLFSLT 142
                   HT  + +V F  D    V+ S D  V+ W+    + L ++T
Sbjct: 205 RPVHQLHGHTEAITAVQF--DEGKAVSGSADGDVRTWALDTGQCLLTMT 65

 Score = 49.7 bits (117), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 27/82 (32%), Positives = 42/82 (51%)
 Frame = -2

Query: 7   EDPSLERHFKGHRDAVTCVDFSLNTKHLASGSMDSTLMIWHMKSQSRAYRFTGHKDAVTC 66
           ++  L    +GH D V CV   +  + + SGS D TL++W + +    ++  GH +A+T 
Sbjct: 334 KNTCLLHTLRGHNDDVECV--CIYGRRVVSGSWDKTLIVWEVDTGRPVHQLHGHTEAITA 161

Query: 67  VNFSPSGHLLASGSRDKTVRIW 88
           V F     +  SGS D  VR W
Sbjct: 160 VQFDEGKAV--SGSADGDVRTW 101

 Score = 42.0 bits (97), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 30/107 (28%), Positives = 48/107 (44%)
 Frame = -2

Query: 74  HLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSLVTASDDKTVKVWSTH 133
           +++ S + D+T+R+W           R H   V  V  C  G+ +V+ S DKT+ VW   
Sbjct: 385 NMIISAATDRTLRVWCLKNTCLLHTLRGHNDDVECV--CIYGRRVVSGSWDKTLIVWEVD 212

Query: 134 RQRFLFSLTQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKTSRECI 180
             R +  L  H   +   +F  D    VS S D  V+ W   + +C+
Sbjct: 211 TGRPVHQLHGHTEAITAVQF--DEGKAVSGSADGDVRTWALDTGQCL 77

 Score = 41.6 bits (96), Expect = 6e-04,   Method: Compositional matrix adjust.
 Identities = 30/105 (28%), Positives = 49/105 (46%)
 Frame = -2

Query: 118 LVTASDDKTVKVWSTHRQRFLFSLTQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKTSR 177
           +++A+ D+T++VW       L +L  H + V C      GR +VS S DKT+ +W+  + 
Sbjct: 379 IISAATDRTLRVWCLKNTCLLHTLRGHNDDVECVCIY--GRRVVSGSWDKTLIVWEVDTG 206

Query: 178 ECIHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDARTHRLL 222
             +H    H   +T V F        +A  D  V+ W   T + L
Sbjct: 205 RPVHQLHGHTEAITAVQFDEGKAVSGSA--DGDVRTWALDTGQCL 77

 Score = 38.5 bits (88), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 27/109 (24%), Positives = 53/109 (48%)
 Frame = -2

Query: 159 LIVSASDDKTVKLWDKTSRECIHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDART 218
           +I+SA+ D+T+++W   +   +H+   H   V  V  +  G  + +   D T+ VW+  T
Sbjct: 382 MIISAATDRTLRVWCLKNTCLLHTLRGHNDDVECVCIY--GRRVVSGSWDKTLIVWEVDT 209

Query: 219 HRLLQHYQLHSAAVNALSFHPSGNYLITASSDSTLKILDLMEGRLLYTL 267
            R +     H+ A+ A+ F       ++ S+D  ++   L  G+ L T+
Sbjct: 208 GRPVHQLHGHTEAITAVQFDEGKA--VSGSADGDVRTWALDTGQCLLTM 68
>11493
          Length = 535

 Score = 49.7 bits (117), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 26/109 (23%), Positives = 48/109 (44%), Gaps = 2/109 (1%)
 Frame = -2

Query: 106 VRSVHFCSDGQSLVTASDDKTVKVW--STHRQRFLFSLTQHINWVRCAKFSPDGRLIVSA 163
           +RSV    DG++L+   +   + +W  ++   R    LT           SPD ++  S 
Sbjct: 330 IRSVKLLPDGRTLIVGGEASNLSIWDLASPTPRIKAELTSAAPACYALAISPDSKVCFSC 151

Query: 164 SDDKTVKLWDKTSRECIHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVK 212
             D  + +WD  +   +  +  H    + +D  P G+ +   G+DNTV+
Sbjct: 150 CSDGNIAVWDLHNEILVRQFQGHTDGASCIDISPDGSRLWTGGLDNTVR 4

 Score = 47.0 bits (110), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 27/114 (23%), Positives = 48/114 (42%), Gaps = 2/114 (1%)
 Frame = -2

Query: 143 QHINWVRCAKFSPDGRLIVSASDDKTVKLWDKTSREC-IHSYCEHGGFVTY-VDFHPSGT 200
           Q  N++R  K  PDGR ++   +   + +WD  S    I +         Y +   P   
Sbjct: 345 QRDNYIRSVKLLPDGRTLIVGGEASNLSIWDLASPTPRIKAELTSAAPACYALAISPDSK 166

Query: 201 CIAAAGMDNTVKVWDARTHRLLQHYQLHSAAVNALSFHPSGNYLITASSDSTLK 254
              +   D  + VWD     L++ +Q H+   + +   P G+ L T   D+T++
Sbjct: 165 VCFSCCSDGNIAVWDLHNEILVRQFQGHTDGASCIDISPDGSRLWTGGLDNTVR 4

 Score = 45.8 bits (107), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 23/86 (26%), Positives = 41/86 (47%)
 Frame = -2

Query: 1   MAAPSQEDPSLERHFKGHRDAVTCVDFSLNTKHLASGSMDSTLMIWHMKSQSRAYRFTGH 60
           +A+P+   P ++        A   +  S ++K   S   D  + +W + ++    +F GH
Sbjct: 252 LASPT---PRIKAELTSAAPACYALAISPDSKVCFSCCSDGNIAVWDLHNEILVRQFQGH 82

Query: 61  KDAVTCVNFSPSGHLLASGSRDKTVR 86
            D  +C++ SP G  L +G  D TVR
Sbjct: 81  TDGASCIDISPDGSRLWTGGLDNTVR 4

 Score = 43.5 bits (101), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 26/109 (23%), Positives = 43/109 (39%), Gaps = 2/109 (1%)
 Frame = -2

Query: 189 FVTYVDFHPSGTCIAAAGMDNTVKVWD--ARTHRLLQHYQLHSAAVNALSFHPSGNYLIT 246
           ++  V   P G  +   G  + + +WD  + T R+       + A  AL+  P      +
Sbjct: 333 YIRSVKLLPDGRTLIVGGEASNLSIWDLASPTPRIKAELTSAAPACYALAISPDSKVCFS 154

Query: 247 ASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGEYFASGGSDEQV 295
             SD  + + DL    L+    GH   A+ +  S  G    +GG D  V
Sbjct: 153 CCSDGNIAVWDLHNEILVRQFQGHTDGASCIDISPDGSRLWTGGLDNTV 7
>01249
          Length = 1743

 Score = 49.3 bits (116), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 62/289 (21%), Positives = 110/289 (38%), Gaps = 31/289 (10%)
 Frame = -1

Query: 42   TLMIWHMKSQSRAYRFTGHKDAVTCVNFSPSGHLLASGSRDKTVRIWVPNVKGESTVFRA 101
            ++  W ++S+S    F G   A  C+       LL +      + +W  + K ES     
Sbjct: 1674 SVAAWDIQSRSSVRTFKGQALAAGCLCLRCGHTLLGAAQNKPVIHVWPLSKKDESQHKIV 1495

Query: 102  HTATVRSVHFCSDGQSLVTASDDKTVKVWSTHRQRFLFSLTQHINWVRCAKFSPDGRLIV 161
                V  +    DG     AS  + + +W       L  L    N     +F+ DG   V
Sbjct: 1494 CPGKVSVLVVSPDGL-FCLASISEKIYIWEMTGGS-LVGLLSDFNEATKIQFTDDGSQFV 1321

Query: 162  SASDDKTVKLWD------KTSREC--------IHSYCEHGGFVTYVDFHPSGTC--IAAA 205
             A+    + +WD       TS+          I+++ E    +T +     G    +A++
Sbjct: 1320 VATSSGHLNIWDFARVVTTTSQRARGLKPGRTINAHSEP---ITGLHVGCGGPAARVASS 1150

Query: 206  GMDNTVKVWDARTHRLLQHYQLHSAAVNALSFHPSGNYLITASSDSTLKILDLMEGRLLY 265
              D T K+WD  +  LL+   ++   V  L      ++L+ A  D+   +   + G++  
Sbjct: 1149 SSDGTCKLWDMLSGALLR-TMVYETGVGCLIMDKQEHFLL-AGLDNGDILCSPLFGQISQ 976

Query: 266  T---------------LHGHQGPATTVAFSRTGEYFASGGSDEQVMVWK 299
            +               L GH    T +AFS  G+  ASG  + +V++W 
Sbjct: 975  SEVFVSKHTTKAGERVLQGHSDAVTCLAFSSDGQRLASGSQNGKVIIWN 829

 Score = 47.0 bits (110), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 20/39 (51%), Positives = 29/39 (74%)
 Frame = -1

Query: 12  ERHFKGHRDAVTCVDFSLNTKHLASGSMDSTLMIWHMKS 50
           ER  +GH DAVTC+ FS + + LASGS +  ++IW+M+S
Sbjct: 936 ERVLQGHSDAVTCLAFSSDGQRLASGSQNGKVIIWNMES 820

 Score = 35.8 bits (81), Expect = 0.033,   Method: Compositional matrix adjust.
 Identities = 31/135 (22%), Positives = 52/135 (38%), Gaps = 16/135 (11%)
 Frame = -1

Query: 13   RHFKGHRDAVTCVDFSLN--TKHLASGSMDSTLMIWHMKSQSRAYRFTGHKDAVTCVNFS 70
            R    H + +T +          +AS S D T  +W M S +   R   ++  V C+   
Sbjct: 1230 RTINAHSEPITGLHVGCGGPAARVASSSSDGTCKLWDMLSGA-LLRTMVYETGVGCLIMD 1054

Query: 71   PSGHLLASGSRDKTV------------RIWVPN--VKGESTVFRAHTATVRSVHFCSDGQ 116
               H L +G  +  +             ++V     K    V + H+  V  + F SDGQ
Sbjct: 1053 KQEHFLLAGLDNGDILCSPLFGQISQSEVFVSKHTTKAGERVLQGHSDAVTCLAFSSDGQ 874

Query: 117  SLVTASDDKTVKVWS 131
             L + S +  V +W+
Sbjct: 873  RLASGSQNGKVIIWN 829

 Score = 28.1 bits (61), Expect = 5.9,   Method: Compositional matrix adjust.
 Identities = 13/38 (34%), Positives = 20/38 (52%)
 Frame = -1

Query: 141 LTQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKTSRE 178
           L  H + V C  FS DG+ + S S +  V +W+  S +
Sbjct: 927 LQGHSDAVTCLAFSSDGQRLASGSQNGKVIIWNMESGD 814
>16199
          Length = 694

 Score = 48.9 bits (115), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 22/52 (42%), Positives = 29/52 (55%)
 Frame = +2

Query: 231 AVNALSFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRT 282
           A+    FHP G    T + DS +KI DL E   +    GHQGP T+++FS T
Sbjct: 77  ALTCAQFHPDGLIFATGTEDSVIKIWDLKERANVANFQGHQGPVTSISFSET 232

 Score = 42.7 bits (99), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 17/53 (32%), Positives = 30/53 (56%)
 Frame = +2

Query: 148 VRCAKFSPDGRLIVSASDDKTVKLWDKTSRECIHSYCEHGGFVTYVDFHPSGT 200
           + CA+F PDG +  + ++D  +K+WD   R  + ++  H G VT + F  + T
Sbjct: 80  LTCAQFHPDGLIFATGTEDSVIKIWDLKERANVANFQGHQGPVTSISFSETDT 238

 Score = 42.7 bits (99), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 29/104 (27%), Positives = 51/104 (49%), Gaps = 1/104 (0%)
 Frame = +1

Query: 156 DGRLIVSASDDKTVKLWDKTSRECIHSYCEHGGF-VTYVDFHPSGTCIAAAGMDNTVKVW 214
           +G  + ++++D  VKLWD    +   +      + V  + F  SGT +A AG D  V+V+
Sbjct: 229 NGYYLATSAEDSVVKLWDLRKLKNFKTLQLGDKYEVKALCFDQSGTYLAVAGSD--VRVY 402

Query: 215 DARTHRLLQHYQLHSAAVNALSFHPSGNYLITASSDSTLKILDL 258
             +    L  +  H+A    + F  + N++ +AS D +LK   L
Sbjct: 403 LCKQWNELAVFNDHTATATGVRFGTNANFIASASMDRSLKFFGL 534

 Score = 42.0 bits (97), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 18/50 (36%), Positives = 29/50 (58%)
 Frame = +2

Query: 21  AVTCVDFSLNTKHLASGSMDSTLMIWHMKSQSRAYRFTGHKDAVTCVNFS 70
           A+TC  F  +    A+G+ DS + IW +K ++    F GH+  VT ++FS
Sbjct: 77  ALTCAQFHPDGLIFATGTEDSVIKIWDLKERANVANFQGHQGPVTSISFS 226

 Score = 40.4 bits (93), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 16/49 (32%), Positives = 25/49 (51%)
 Frame = +2

Query: 63  AVTCVNFSPSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHF 111
           A+TC  F P G + A+G+ D  ++IW    +     F+ H   V S+ F
Sbjct: 77  ALTCAQFHPDGLIFATGTEDSVIKIWDLKERANVANFQGHQGPVTSISF 223

 Score = 38.9 bits (89), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 18/63 (28%), Positives = 29/63 (46%), Gaps = 4/63 (6%)
 Frame = +2

Query: 179 CIHSYCEHGG----FVTYVDFHPSGTCIAAAGMDNTVKVWDARTHRLLQHYQLHSAAVNA 234
           C    C+  G     +T   FHP G   A    D+ +K+WD +    + ++Q H   V +
Sbjct: 35  C*PKVCDKSGPSVPALTCAQFHPDGLIFATGTEDSVIKIWDLKERANVANFQGHQGPVTS 214

Query: 235 LSF 237
           +SF
Sbjct: 215 ISF 223
>31384
          Length = 474

 Score = 48.5 bits (114), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 33/89 (37%), Positives = 45/89 (50%), Gaps = 6/89 (6%)
 Frame = -1

Query: 62  DAVTCVNFSPSG---HLLASGSRDKTVRIWVPNVKGESTVFRA---HTATVRSVHFCSDG 115
           D+V+C+ FSP       L SGS D  V  W     G+ T+ +A   HT  V  V +  DG
Sbjct: 273 DSVSCLKFSPGALPSTFLISGSWDNKVSCWEVQQSGQ-TIPKAQQTHTGPVLDVDWSDDG 97

Query: 116 QSLVTASDDKTVKVWSTHRQRFLFSLTQH 144
             + TAS DKT KVW  +  + +  + QH
Sbjct: 96  TKVFTASCDKTAKVWDLNSNQCM-QIAQH 13

 Score = 35.4 bits (80), Expect = 0.043,   Method: Compositional matrix adjust.
 Identities = 21/66 (31%), Positives = 31/66 (46%), Gaps = 2/66 (3%)
 Frame = -1

Query: 118 LVTASDDKTVKVWSTHR--QRFLFSLTQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKT 175
           L++ S D  V  W   +  Q    +   H   V    +S DG  + +AS DKT K+WD  
Sbjct: 222 LISGSWDNKVSCWEVQQSGQTIPKAQQTHTGPVLDVDWSDDGTKVFTASCDKTAKVWDLN 43

Query: 176 SRECIH 181
           S +C+ 
Sbjct: 42  SNQCMQ 25

 Score = 34.7 bits (78), Expect = 0.063,   Method: Compositional matrix adjust.
 Identities = 23/74 (31%), Positives = 38/74 (51%), Gaps = 5/74 (6%)
 Frame = -1

Query: 20  DAVTCVDFS---LNTKHLASGSMDSTLMIWHMK--SQSRAYRFTGHKDAVTCVNFSPSGH 74
           D+V+C+ FS   L +  L SGS D+ +  W ++   Q+       H   V  V++S  G 
Sbjct: 273 DSVSCLKFSPGALPSTFLISGSWDNKVSCWEVQQSGQTIPKAQQTHTGPVLDVDWSDDGT 94

Query: 75  LLASGSRDKTVRIW 88
            + + S DKT ++W
Sbjct: 93  KVFTASCDKTAKVW 52
>15780
          Length = 735

 Score = 48.1 bits (113), Expect = 6e-06,   Method: Compositional matrix adjust.
 Identities = 20/57 (35%), Positives = 33/57 (57%)
 Frame = -1

Query: 32  KHLASGSMDSTLMIWHMKSQSRAYRFTGHKDAVTCVNFSPSGHLLASGSRDKTVRIW 88
           K+L++   D T+++W + S +     T H D V  + FS  G +LASG  D ++R+W
Sbjct: 735 KYLSTAGADHTVIVWDIASGTAVAHLTAHTDTVYALCFSRDGTVLASGGMDNSIRLW 565

 Score = 41.2 bits (95), Expect = 8e-04,   Method: Compositional matrix adjust.
 Identities = 19/58 (32%), Positives = 31/58 (53%)
 Frame = -1

Query: 158 RLIVSASDDKTVKLWDKTSRECIHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWD 215
           + + +A  D TV +WD  S   +     H   V  + F   GT +A+ GMDN++++WD
Sbjct: 735 KYLSTAGADHTVIVWDIASGTAVAHLTAHTDTVYALCFSRDGTVLASGGMDNSIRLWD 562

 Score = 40.8 bits (94), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 20/56 (35%), Positives = 28/56 (50%)
 Frame = -1

Query: 243 YLITASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGEYFASGGSDEQVMVW 298
           YL TA +D T+ + D+  G  +  L  H      + FSR G   ASGG D  + +W
Sbjct: 732 YLSTAGADHTVIVWDIASGTAVAHLTAHTDTVYALCFSRDGTVLASGGMDNSIRLW 565

 Score = 32.0 bits (71), Expect = 0.44,   Method: Compositional matrix adjust.
 Identities = 18/61 (29%), Positives = 31/61 (50%), Gaps = 2/61 (3%)
 Frame = -1

Query: 76  LASGSRDKTVRIWVPNVKGESTV--FRAHTATVRSVHFCSDGQSLVTASDDKTVKVWSTH 133
           L++   D TV +W  ++   + V    AHT TV ++ F  DG  L +   D ++++W   
Sbjct: 729 LSTAGADHTVIVW--DIASGTAVAHLTAHTDTVYALCFSRDGTVLASGGMDNSIRLWDLA 556

Query: 134 R 134
           R
Sbjct: 555 R 553

 Score = 30.8 bits (68), Expect = 1.0,   Method: Compositional matrix adjust.
 Identities = 13/35 (37%), Positives = 20/35 (57%)
 Frame = -1

Query: 14  HFKGHRDAVTCVDFSLNTKHLASGSMDSTLMIWHM 48
           H   H D V  + FS +   LASG MD+++ +W +
Sbjct: 663 HLTAHTDTVYALCFSRDGTVLASGGMDNSIRLWDL 559
>15337
          Length = 860

 Score = 47.8 bits (112), Expect = 8e-06,   Method: Compositional matrix adjust.
 Identities = 22/81 (27%), Positives = 38/81 (46%)
 Frame = -1

Query: 218 THRLLQHYQLHSAAVNALSFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATTV 277
           T   L  + + + A++  +F P   YL     D  L++ +     L+ T+  + G    V
Sbjct: 362 TRNPLYRWVVGTGAISEFAFSPCSRYLAVVGQDGHLRVFNYNSMELIGTMKSYFGGLLCV 183

Query: 278 AFSRTGEYFASGGSDEQVMVW 298
            +S  G+Y  +GG D+ V VW
Sbjct: 182 CWSPDGKYIVTGGEDDLVTVW 120

 Score = 47.8 bits (112), Expect = 9e-06,   Method: Compositional matrix adjust.
 Identities = 31/136 (22%), Positives = 56/136 (41%)
 Frame = -1

Query: 18  HRDAVTCVDFSLNTKHLASGSMDSTLMIWHMKSQSRAYRFTGHKDAVTCVNFSPSGHLLA 77
           + + + C     N +    G   S        +++  YR+     A++   FSP    LA
Sbjct: 458 YNEELPCGQTPPNYQPFKQGEGYSVFTCKTKSTRNPLYRWVVGTGAISEFAFSPCSRYLA 279

Query: 78  SGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSLVTASDDKTVKVWSTHRQRF 137
              +D  +R++  N        +++   +  V +  DG+ +VT  +D  V VWS H +R 
Sbjct: 278 VVGQDGHLRVFNYNSMELIGTMKSYFGGLLCVCWSPDGKYIVTGGEDDLVTVWSFHEKRV 99

Query: 138 LFSLTQHINWVRCAKF 153
           +     H +WV    F
Sbjct: 98  VCRGHGHKSWVNVVAF 51

 Score = 47.4 bits (111), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 23/106 (21%), Positives = 49/106 (46%)
 Frame = -1

Query: 174 KTSRECIHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDARTHRLLQHYQLHSAAVN 233
           K++R  ++ +    G ++   F P    +A  G D  ++V++  +  L+   + +   + 
Sbjct: 368 KSTRNPLYRWVVGTGAISEFAFSPCSRYLAVVGQDGHLRVFNYNSMELIGTMKSYFGGLL 189

Query: 234 ALSFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATTVAF 279
            + + P G Y++T   D  + +    E R++   HGH+     VAF
Sbjct: 188 CVCWSPDGKYIVTGGEDDLVTVWSFHEKRVVCRGHGHKSWVNVVAF 51

 Score = 40.0 bits (92), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 23/85 (27%), Positives = 39/85 (45%)
 Frame = -1

Query: 153 FSPDGRLIVSASDDKTVKLWDKTSRECIHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVK 212
           FSP  R +     D  +++++  S E I +   + G +  V + P G  I   G D+ V 
Sbjct: 305 FSPCSRYLAVVGQDGHLRVFNYNSMELIGTMKSYFGGLLCVCWSPDGKYIVTGGEDDLVT 126

Query: 213 VWDARTHRLLQHYQLHSAAVNALSF 237
           VW     R++     H + VN ++F
Sbjct: 125 VWSFHEKRVVCRGHGHKSWVNVVAF 51

 Score = 31.2 bits (69), Expect = 0.74,   Method: Compositional matrix adjust.
 Identities = 15/54 (27%), Positives = 25/54 (46%)
 Frame = -1

Query: 16  KGHRDAVTCVDFSLNTKHLASGSMDSTLMIWHMKSQSRAYRFTGHKDAVTCVNF 69
           K +   + CV +S + K++ +G  D  + +W    +    R  GHK  V  V F
Sbjct: 212 KSYFGGLLCVCWSPDGKYIVTGGEDDLVTVWSFHEKRVVCRGHGHKSWVNVVAF 51
>37180
          Length = 681

 Score = 47.4 bits (111), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 28/81 (34%), Positives = 42/81 (51%), Gaps = 1/81 (1%)
 Frame = +1

Query: 57  FTGHKDAVTCVNFSPSGHLLASGSRDKTVRIW-VPNVKGESTVFRAHTATVRSVHFCSDG 115
             GH   ++ V+  P+  L+ + S+D T R+W   +      VF+ HT  V S  F S G
Sbjct: 7   LNGHDQELSDVHAHPTQRLVVTSSKDMTFRLWDFRDSALLVNVFQGHTQPVTSAVFAS-G 183

Query: 116 QSLVTASDDKTVKVWSTHRQR 136
             +V+ SDD+TV+VW     R
Sbjct: 184 DKVVSGSDDRTVRVWDMRNMR 246

 Score = 39.3 bits (90), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 26/78 (33%), Positives = 39/78 (50%), Gaps = 1/78 (1%)
 Frame = +1

Query: 97  TVFRAHTATVRSVHFCSDGQSLVTASDDKTVKVWSTHRQRFLFSLTQ-HINWVRCAKFSP 155
            V   H   +  VH     + +VT+S D T ++W       L ++ Q H   V  A F+ 
Sbjct: 1   NVLNGHDQELSDVHAHPTQRLVVTSSKDMTFRLWDFRDSALLVNVFQGHTQPVTSAVFAS 180

Query: 156 DGRLIVSASDDKTVKLWD 173
            G  +VS SDD+TV++WD
Sbjct: 181 -GDKVVSGSDDRTVRVWD 231

 Score = 37.7 bits (86), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 20/68 (29%), Positives = 37/68 (54%), Gaps = 1/68 (1%)
 Frame = +1

Query: 196 HPSGTCIAAAGMDNTVKVWDARTHRLLQH-YQLHSAAVNALSFHPSGNYLITASSDSTLK 254
           HP+   +  +  D T ++WD R   LL + +Q H+  V +  F  SG+ +++ S D T++
Sbjct: 46  HPTQRLVVTSSKDMTFRLWDFRDSALLVNVFQGHTQPVTSAVF-ASGDKVVSGSDDRTVR 222

Query: 255 ILDLMEGR 262
           + D+   R
Sbjct: 223 VWDMRNMR 246

 Score = 27.7 bits (60), Expect = 9.8,   Method: Compositional matrix adjust.
 Identities = 14/36 (38%), Positives = 21/36 (58%)
 Frame = +1

Query: 15  FKGHRDAVTCVDFSLNTKHLASGSMDSTLMIWHMKS 50
           F+GH   VT   F+   K + SGS D T+ +W M++
Sbjct: 136 FQGHTQPVTSAVFASGDK-VVSGSDDRTVRVWDMRN 240
>30295
          Length = 593

 Score = 47.0 bits (110), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 35/142 (24%), Positives = 65/142 (45%), Gaps = 4/142 (2%)
 Frame = +2

Query: 120 TASDDKTVKVWSTHRQRFLFSLTQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKTSREC 179
           TAS D   ++    + R   +L  H+  +    ++ D R +VSAS D  + +WD  +   
Sbjct: 182 TASYDSVGRI----QMRTRRTLRXHLAKIYAMHWATDSRNLVSASQDGKLIVWDGYTTNK 349

Query: 180 IHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDARTH----RLLQHYQLHSAAVNAL 235
           +H+      +V    + PSG  +A  G+DN   ++  +T     R+ +    H+  ++  
Sbjct: 350 VHAIPLRSSWVMTCAYAPSGGYVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCC 529

Query: 236 SFHPSGNYLITASSDSTLKILD 257
            F    N ++T+S D T  + D
Sbjct: 530 RF-IDDNQIVTSSGDMTCALWD 592

 Score = 46.2 bits (108), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 27/121 (22%), Positives = 54/121 (44%), Gaps = 4/121 (3%)
 Frame = +2

Query: 99  FRAHTATVRSVHFCSDGQSLVTASDDKTVKVWSTHRQRFLFSLTQHINWVRCAKFSPDGR 158
            R H A + ++H+ +D ++LV+AS D  + VW  +    + ++    +WV    ++P G 
Sbjct: 233 LRXHLAKIYAMHWATDSRNLVSASQDGKLIVWDGYTTNKVHAIPLRSSWVMTCAYAPSGG 412

Query: 159 LIVSASDDKTVKLWDKTSRE----CIHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVW 214
            +     D    ++   +RE           H G+++   F      + ++G D T  +W
Sbjct: 413 YVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFIDDNQIVTSSG-DMTCALW 589

Query: 215 D 215
           D
Sbjct: 590 D 592

 Score = 44.7 bits (104), Expect = 6e-05,   Method: Compositional matrix adjust.
 Identities = 30/123 (24%), Positives = 55/123 (44%), Gaps = 4/123 (3%)
 Frame = +2

Query: 12  ERHFKGHRDAVTCVDFSLNTKHLASGSMDSTLMIWHMKSQSRAYRFTGHKDAVTCVNFSP 71
            R  + H   +  + ++ ++++L S S D  L++W   + ++ +        V    ++P
Sbjct: 224 RRTLRXHLAKIYAMHWATDSRNLVSASQDGKLIVWDGYTTNKVHAIPLRSSWVMTCAYAP 403

Query: 72  SGHLLASGSRDKTVRIW-VPNVKGESTVFR---AHTATVRSVHFCSDGQSLVTASDDKTV 127
           SG  +A G  D    I+ +   +G   V R    HT  +    F  D Q +VT+S D T 
Sbjct: 404 SGGYVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFIDDNQ-IVTSSGDMTC 580

Query: 128 KVW 130
            +W
Sbjct: 581 ALW 589

 Score = 35.4 bits (80), Expect = 0.038,   Method: Compositional matrix adjust.
 Identities = 28/101 (27%), Positives = 41/101 (40%), Gaps = 4/101 (3%)
 Frame = +2

Query: 202 IAAAGMDNTVKVWDARTHRLLQHYQLHSAAVNALSFHPSGNYLITASSDSTLKILDLM-- 259
           + +A  D  + VWD  T   +    L S+ V   ++ PSG Y+     D+   I  L   
Sbjct: 290 LVSASQDGKLIVWDGYTTNKVHAIPLRSSWVMTCAYAPSGGYVACGGLDNICSIYSLKTR 469

Query: 260 EG--RLLYTLHGHQGPATTVAFSRTGEYFASGGSDEQVMVW 298
           EG  R+   L GH G  +   F    +   S G D    +W
Sbjct: 470 EGNVRVSRELPGHTGYLSCCRFIDDNQIVTSSG-DMTCALW 589
>31864
          Length = 545

 Score = 46.6 bits (109), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 35/141 (24%), Positives = 62/141 (43%), Gaps = 15/141 (10%)
 Frame = +2

Query: 172 WD-KTSRECIHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDARTHRLLQHYQLHSA 230
           WD +  ++ + S  +H G +  +     GT    A  D T K++D+ +   L+ Y+    
Sbjct: 2   WDVRKGQKVVDSGVDHTGGINDMQLSKDGTMFVTASKDTTAKLFDSESLMCLKTYKTERP 181

Query: 231 AVNALSFHPSGNYLITASSDSTLKI---------LDLMEGRLLYT-----LHGHQGPATT 276
            VN+ +  P  ++++       +++          D     L+Y      L GH GP  +
Sbjct: 182 -VNSAAISPILDHVVLGGGQDAMEVTTTSTKAGKFDSRFFHLIYEEEFARLKGHFGPINS 358

Query: 277 VAFSRTGEYFASGGSDEQVMV 297
           +AF   G+ +ASGG D  V V
Sbjct: 359 LAFHPDGKSYASGGEDGFVRV 421

 Score = 31.2 bits (69), Expect = 0.88,   Method: Compositional matrix adjust.
 Identities = 17/59 (28%), Positives = 25/59 (42%)
 Frame = +2

Query: 29  LNTKHLASGSMDSTLMIWHMKSQSRAYRFTGHKDAVTCVNFSPSGHLLASGSRDKTVRI 87
           + T    +G  DS    +H+  +    R  GH   +  + F P G   ASG  D  VR+
Sbjct: 251 VTTTSTKAGKFDSRF--FHLIYEEEFARLKGHFGPINSLAFHPDGKSYASGGEDGFVRV 421
>10162
          Length = 1629

 Score = 46.6 bits (109), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 55/252 (21%), Positives = 92/252 (36%), Gaps = 42/252 (16%)
 Frame = +3

Query: 4   PSQEDPSLERHFKGHRDAVTCVDFSLNTKHLASGSMDSTLMIWHMKSQSRAYRF------ 57
           PSQ D S  +  + H     C     N K++  G  D  + +W +K+ +  + +      
Sbjct: 117 PSQ-DYSKMKMLQSHGQPSLCGKILPNGKYVCVGYSDGVVKLWDLKTGTAVHTWQHSVMP 293

Query: 58  ----------------------TGHKDAVTCVNFSPSGHLLASGSRDKTVRIWVPNVKGE 95
                                      A+ CV+ S    L+ SG  D T +++  +    
Sbjct: 294 EEEMPERNSSDEEDGEEVEVEREEDTVAILCVDCSADNALIMSGCADATAKVFNVSSGKL 473

Query: 96  STVFRAHTA--------TVRSVHFCSDGQSLVTASDDKTVKVW----STHRQRFLFSLTQ 143
            + F    +        +V SV FC       TA++  +V+VW    S  R  F     Q
Sbjct: 474 XSAFNCAASQDSQDKDNSVESVAFCPVSPYAATATNSGSVQVWDLPTSVARHSF-----Q 638

Query: 144 HINWVRCAKFSPDGRLIVSASDDKTVKLWDKTSRECIHSYCEHGGFVTYVDFHPS--GTC 201
           H   V   ++S    L+ +A  D  +++WD  S         H      +DF  +  GTC
Sbjct: 639 HPEGVCKLQWSSSTALLYTACLDGVMRVWDARSGASKAVLTGHARNSCILDFDVTRDGTC 818

Query: 202 IAAAGMDNTVKV 213
           + +   D T +V
Sbjct: 819 LVSGSEDGTARV 854

 Score = 36.2 bits (82), Expect = 0.026,   Method: Compositional matrix adjust.
 Identities = 34/180 (18%), Positives = 66/180 (36%), Gaps = 39/180 (21%)
 Frame = +3

Query: 118 LVTASDDKTVKVWSTHRQRF--LFSLTQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKT 175
           L+  +    V +W    Q +  +  L  H     C K  P+G+ +     D  VKLWD  
Sbjct: 72  LLAGTQGGEVWLWQVPSQDYSKMKMLQSHGQPSLCGKILPNGKYVCVGYSDGVVKLWDLK 251

Query: 176 SRECIHSYCEHGGF-----------------------------VTYVDFHPSGTCIAAAG 206
           +   +H++ +H                                +  VD       I +  
Sbjct: 252 TGTAVHTW-QHSVMPEEEMPERNSSDEEDGEEVEVEREEDTVAILCVDCSADNALIMSGC 428

Query: 207 MDNTVKVWDARTHRLLQHYQLHSA--------AVNALSFHPSGNYLITASSDSTLKILDL 258
            D T KV++  + +L   +   ++        +V +++F P   Y  TA++  ++++ DL
Sbjct: 429 ADATAKVFNVSSGKLXSAFNCAASQDSQDKDNSVESVAFCPVSPYAATATNSGSVQVWDL 608
>21921
          Length = 1341

 Score = 46.2 bits (108), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 25/69 (36%), Positives = 41/69 (59%), Gaps = 1/69 (1%)
 Frame = -1

Query: 144 HINWVRCAKFSPDGRLIVSASDDKTVKLWDKTSRECIHSYCEHGGFVTYVDFHPSGT-CI 202
           H   VR     P G+ +VS SDD T++ W+ +S  C+ +  + GG VT V ++P+ + C+
Sbjct: 486 HTGIVRSICPDPTGQWLVSGSDDGTIRFWEVSSGRCMKT-LQVGGCVTSVAWNPNPSLCV 310

Query: 203 AAAGMDNTV 211
            AA ++ TV
Sbjct: 309 VAATLNTTV 283

 Score = 40.4 bits (93), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 33/100 (33%), Positives = 52/100 (52%), Gaps = 3/100 (3%)
 Frame = -1

Query: 75  LLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSD--GQSLVTASDDKTVKVWST 132
           LL    + K +R   P    ++ V++ HT  VRS+  C D  GQ LV+ SDD T++ W  
Sbjct: 558 LLPKLPKPKDLR---PFPTTQALVYKGHTGIVRSI--CPDPTGQWLVSGSDDGTIRFWEV 394

Query: 133 HRQRFLFSLTQHINWVRCAKFSPDGRL-IVSASDDKTVKL 171
              R + +L Q    V    ++P+  L +V+A+ + TV L
Sbjct: 393 SSGRCMKTL-QVGGCVTSVAWNPNPSLCVVAATLNTTVLL 277

 Score = 33.5 bits (75), Expect = 0.16,   Method: Compositional matrix adjust.
 Identities = 16/74 (21%), Positives = 39/74 (52%)
 Frame = -1

Query: 183 YCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDARTHRLLQHYQLHSAAVNALSFHPSGN 242
           Y  H G V  +   P+G  + +   D T++ W+  + R ++  Q+    V +++++P+ +
Sbjct: 495 YKGHTGIVRSICPDPTGQWLVSGSDDGTIRFWEVSSGRCMKTLQV-GGCVTSVAWNPNPS 319

Query: 243 YLITASSDSTLKIL 256
             + A++ +T  +L
Sbjct: 318 LCVVAATLNTTVLL 277

 Score = 32.7 bits (73), Expect = 0.27,   Method: Compositional matrix adjust.
 Identities = 14/37 (37%), Positives = 20/37 (54%)
 Frame = -1

Query: 52  SRAYRFTGHKDAVTCVNFSPSGHLLASGSRDKTVRIW 88
           ++A  + GH   V  +   P+G  L SGS D T+R W
Sbjct: 510 TQALVYKGHTGIVRSICPDPTGQWLVSGSDDGTIRFW 400

 Score = 27.7 bits (60), Expect = 9.6,   Method: Compositional matrix adjust.
 Identities = 32/136 (23%), Positives = 57/136 (41%), Gaps = 1/136 (0%)
 Frame = -1

Query: 15  FKGHRDAVTCVDFSLNTKHLASGSMDSTLMIWHMKSQSRAYRFTGHKDAVTCVNFSPSGH 74
           +KGH   V  +      + L SGS D T+  W + S  R  +       VT V ++P+  
Sbjct: 495 YKGHTGIVRSICPDPTGQWLVSGSDDGTIRFWEV-SSGRCMKTLQVGGCVTSVAWNPNPS 319

Query: 75  L-LASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSLVTASDDKTVKVWSTH 133
           L + + + + TV +  P +  +  V              S+   L+ AS+D+     S+ 
Sbjct: 318 LCVVAATLNTTVLLINPGLGDKLVV--------------SNTDKLLLASEDQASS--SSE 187

Query: 134 RQRFLFSLTQHINWVR 149
           ++       Q ++WVR
Sbjct: 186 KE-------QPVDWVR 160
>21960
          Length = 756

 Score = 45.1 bits (105), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 22/68 (32%), Positives = 37/68 (54%), Gaps = 2/68 (2%)
 Frame = +1

Query: 149 RCAKFSPDGRLIVSASDDKTVKLWDKTSRECIHSYC--EHGGFVTYVDFHPSGTCIAAAG 206
           R   F P    I+S SDD  +  WDK + E + ++   +  G V  ++ HP+   +A +G
Sbjct: 376 RVNFFGPHSEHIISGSDDGNIFYWDKNT-EAVTNFMKGDDAGVVNCLEQHPTMPVLATSG 552

Query: 207 MDNTVKVW 214
           +D+ VK+W
Sbjct: 553 LDHNVKIW 576

 Score = 42.4 bits (98), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 23/74 (31%), Positives = 38/74 (51%), Gaps = 2/74 (2%)
 Frame = +1

Query: 27  FSLNTKHLASGSMDSTLMIWHMKSQSRAYRFTGHKDA--VTCVNFSPSGHLLASGSRDKT 84
           F  +++H+ SGS D  +  W   +++    F    DA  V C+   P+  +LA+   D  
Sbjct: 388 FGPHSEHIISGSDDGNIFYWDKNTEA-VTNFMKGDDAGVVNCLEQHPTMPVLATSGLDHN 564

Query: 85  VRIWVPNVKGESTV 98
           V+IW P+ K E+ V
Sbjct: 565 VKIWTPSAKPETEV 606
>27681
          Length = 465

 Score = 34.7 bits (78), Expect(2) = 6e-05,   Method: Compositional matrix adjust.
 Identities = 29/91 (31%), Positives = 39/91 (42%), Gaps = 15/91 (16%)
 Frame = +2

Query: 69  FSPSGHLLASGSRDKTVRIW-----VPNVKGESTVFR----------AHTATVRSVHFCS 113
           ++P+  LLASGS D T RIW      PN      V R               V S+ + S
Sbjct: 17  WNPTNDLLASGSGDSTARIWNMTSETPN-NANQLVLRHCIQKGGTEVPSNKDVTSLDWNS 193

Query: 114 DGQSLVTASDDKTVKVWSTHRQRFLFSLTQH 144
           +G  L T S D   ++W T     + +L QH
Sbjct: 194 EGTLLATGSYDGYARLWRTDGH-LVNTLGQH 283

 Score = 29.6 bits (65), Expect(2) = 6e-05,   Method: Compositional matrix adjust.
 Identities = 12/32 (37%), Positives = 18/32 (56%)
 Frame = +3

Query: 152 KFSPDGRLIVSASDDKTVKLWDKTSRECIHSY 183
           K++  G  I+SA  DKT  +WD +S  C   +
Sbjct: 306 KWNKRGNYILSAGVDKTTIIWDASSGSCTQQF 401

 Score = 37.4 bits (85), Expect = 0.010,   Method: Compositional matrix adjust.
 Identities = 26/70 (37%), Positives = 34/70 (48%), Gaps = 15/70 (21%)
 Frame = +2

Query: 34  LASGSMDSTLMIWHMKS---------------QSRAYRFTGHKDAVTCVNFSPSGHLLAS 78
           LASGS DST  IW+M S               Q        +KD VT ++++  G LLA+
Sbjct: 38  LASGSGDSTARIWNMTSETPNNANQLVLRHCIQKGGTEVPSNKD-VTSLDWNSEGTLLAT 214

Query: 79  GSRDKTVRIW 88
           GS D   R+W
Sbjct: 215 GSYDGYARLW 244
>19863
          Length = 502

 Score = 44.3 bits (103), Expect = 9e-05,   Method: Compositional matrix adjust.
 Identities = 22/56 (39%), Positives = 31/56 (55%)
 Frame = +1

Query: 33 HLASGSMDSTLMIWHMKSQSRAYRFTGHKDAVTCVNFSPSGHLLASGSRDKTVRIW 88
           L SGS D ++++W +++  +  R  GH   V  V+FS     L S S D TVRIW
Sbjct: 13 QLVSGSSDMSIVVWDVENGVQKLRLQGHAGWVNDVHFSQDQCWLLSCSNDNTVRIW 180

 Score = 43.1 bits (100), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 24/73 (32%), Positives = 34/73 (46%)
 Frame = +1

Query: 114 DGQSLVTASDDKTVKVWSTHRQRFLFSLTQHINWVRCAKFSPDGRLIVSASDDKTVKLWD 173
           DG  LV+ S D ++ VW          L  H  WV    FS D   ++S S+D TV++W+
Sbjct: 4   DGLQLVSGSSDMSIVVWDVENGVQKLRLQGHAGWVNDVHFSQDQCWLLSCSNDNTVRIWN 183

Query: 174 KTSRECIHSYCEH 186
               + I    EH
Sbjct: 184 IEESDQIPIVMEH 222

 Score = 39.7 bits (91), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 20/72 (27%), Positives = 34/72 (47%)
 Frame = +1

Query: 73  GHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSLVTASDDKTVKVWST 132
           G  L SGS D ++ +W      +    + H   V  VHF  D   L++ S+D TV++W+ 
Sbjct: 7   GLQLVSGSSDMSIVVWDVENGVQKLRLQGHAGWVNDVHFSQDQCWLLSCSNDNTVRIWNI 186

Query: 133 HRQRFLFSLTQH 144
                +  + +H
Sbjct: 187 EESDQIPIVMEH 222

 Score = 35.8 bits (81), Expect = 0.034,   Method: Compositional matrix adjust.
 Identities = 18/59 (30%), Positives = 28/59 (47%)
 Frame = +1

Query: 241 GNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGEYFASGGSDEQVMVWK 299
           G  L++ SSD ++ + D+  G     L GH G    V FS+   +  S  +D  V +W 
Sbjct: 7   GLQLVSGSSDMSIVVWDVENGVQKLRLQGHAGWVNDVHFSQDQCWLLSCSNDNTVRIWN 183

 Score = 32.3 bits (72), Expect = 0.32,   Method: Compositional matrix adjust.
 Identities = 18/60 (30%), Positives = 29/60 (48%)
 Frame = +1

Query: 156 DGRLIVSASDDKTVKLWDKTSRECIHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWD 215
           DG  +VS S D ++ +WD  +         H G+V  V F      + +   DNTV++W+
Sbjct: 4   DGLQLVSGSSDMSIVVWDVENGVQKLRLQGHAGWVNDVHFSQDQCWLLSCSNDNTVRIWN 183
>17298
          Length = 476

 Score = 43.5 bits (101), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 28/105 (26%), Positives = 44/105 (41%), Gaps = 17/105 (16%)
 Frame = -1

Query: 167 KTVKLWDK-----------------TSRECIHSYCEHGGFVTYVDFHPSGTCIAAAGMDN 209
           KTVK+W +                  S + +  Y +H G V  V F+   T I +  +DN
Sbjct: 323 KTVKMWQRRQVCWHICDGVVVGNNVASGQALRKYRDHAGTVNCVKFNEESTVILSGSLDN 144

Query: 210 TVKVWDARTHRLLQHYQLHSAAVNALSFHPSGNYLITASSDSTLK 254
           TV+ WD R+        L  A  +  S   S   ++T S+D  ++
Sbjct: 143 TVRAWDTRSRSHTPIQVLDEATDSVTSIQVSDYEILTGSADGRVR 9

 Score = 35.8 bits (81), Expect = 0.036,   Method: Compositional matrix adjust.
 Identities = 23/76 (30%), Positives = 38/76 (50%), Gaps = 2/76 (2%)
 Frame = -1

Query: 13  RHFKGHRDAVTCVDFSLNTKHLASGSMDSTLMIWHMKSQSRA--YRFTGHKDAVTCVNFS 70
           R ++ H   V CV F+  +  + SGS+D+T+  W  +S+S           D+VT +  S
Sbjct: 230 RKYRDHAGTVNCVKFNEESTVILSGSLDNTVRAWDTRSRSHTPIQVLDEATDSVTSIQVS 51

Query: 71  PSGHLLASGSRDKTVR 86
              + + +GS D  VR
Sbjct: 50  D--YEILTGSADGRVR 9

 Score = 33.5 bits (75), Expect = 0.14,   Method: Compositional matrix adjust.
 Identities = 15/34 (44%), Positives = 20/34 (58%)
 Frame = -1

Query: 144 HINWVRCAKFSPDGRLIVSASDDKTVKLWDKTSR 177
           H   V C KF+ +  +I+S S D TV+ WD  SR
Sbjct: 215 HAGTVNCVKFNEESTVILSGSLDNTVRAWDTRSR 114

 Score = 32.0 bits (71), Expect = 0.40,   Method: Compositional matrix adjust.
 Identities = 16/36 (44%), Positives = 19/36 (52%)
 Frame = -1

Query: 53  RAYRFTGHKDAVTCVNFSPSGHLLASGSRDKTVRIW 88
           R YR   H   V CV F+    ++ SGS D TVR W
Sbjct: 230 RKYR--DHAGTVNCVKFNEESTVILSGSLDNTVRAW 129
>19140
          Length = 573

 Score = 43.1 bits (100), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 32/119 (26%), Positives = 50/119 (42%), Gaps = 3/119 (2%)
 Frame = -3

Query: 15  FKGHRDAVTCVDFSLNTKHLASGSMDSTLMIWHMKSQSRAYRFTGHKDAVTCVNFSPSGH 74
            KGH D V  +  + +     SGS D T+ +W +  Q     F  H + V  +  + S  
Sbjct: 499 LKGHTDNVKALVLNRDGTQCLSGSSDGTIRLWSLGQQRCVATFRVHDEGVWALQANESFT 320

Query: 75  LLASGSRDKTVRIWVPNVKGEST--VFRAHTATVRSVHFC-SDGQSLVTASDDKTVKVW 130
            L SG RD   ++W  ++K      +     A V  +    +D  SL  A+ D  +K W
Sbjct: 319 TLYSGGRDH--QVWATDIKNPDNRELICEEKAPVLKLELTPTDPPSLWVATTDSCIKNW 149

 Score = 37.7 bits (86), Expect = 0.009,   Method: Compositional matrix adjust.
 Identities = 27/120 (22%), Positives = 50/120 (41%), Gaps = 1/120 (0%)
 Frame = -3

Query: 99  FRAHTATVRSVHFCSDGQSLVTASDDKTVKVWSTHRQRFLFSLTQHINWVRCAKFSPDGR 158
            + HT  V+++    DG   ++ S D T+++WS  +QR + +   H   V   + +    
Sbjct: 499 LKGHTDNVKALVLNRDGTQCLSGSSDGTIRLWSLGQQRCVATFRVHDEGVWALQANESFT 320

Query: 159 LIVSASDDKTVKLWDKTSRECIHSYCEHGGFVTYVDFHPSG-TCIAAAGMDNTVKVWDAR 217
            + S   D  V   D  + +     CE    V  ++  P+    +  A  D+ +K W  R
Sbjct: 319 TLYSGGRDHQVWATDIKNPDNRELICEEKAPVLKLELTPTDPPSLWVATTDSCIKNWPVR 140

 Score = 34.7 bits (78), Expect = 0.077,   Method: Compositional matrix adjust.
 Identities = 32/135 (23%), Positives = 55/135 (40%), Gaps = 4/135 (2%)
 Frame = -3

Query: 53  RAYRFTGHKDAVTCVNFSPSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFC 112
           +  +  GH D V  +  +  G    SGS D T+R+W    +     FR H   V ++   
Sbjct: 511 KLMKLKGHTDNVKALVLNRDGTQCLSGSSDGTIRLWSLGQQRCVATFRVHDEGVWALQAN 332

Query: 113 SDGQSLVTASDDKTVKVWSTH----RQRFLFSLTQHINWVRCAKFSPDGRLIVSASDDKT 168
               +L +   D   +VW+T       R L           C + +P  +L ++ +D  +
Sbjct: 331 ESFTTLYSGGRDH--QVWATDIKNPDNRELI----------CEEKAPVLKLELTPTDPPS 188

Query: 169 VKLWDKTSRECIHSY 183
             LW  T+  CI ++
Sbjct: 187 --LWVATTDSCIKNW 149
>39204
          Length = 1684

 Score = 42.7 bits (99), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 48/190 (25%), Positives = 79/190 (41%), Gaps = 19/190 (10%)
 Frame = -2

Query: 142  TQHINWVRCAKFSP------DGRLIVSASDDKTVKLWDKTSR----ECIHSY-CEHGGF- 189
            T H   VRC +F P         ++VSA DD   KLW  T+R    + +  + CE  G  
Sbjct: 1278 TPHYKAVRCLRFKPVTDSESPAPMLVSAGDDGMFKLWTLTTRTHHGKPVERWTCESVGHY 1099

Query: 190  ----VTYVDFHPSGTCIAAAGMDNTVKVWDARTHRLLQHYQLHSAAVNALSF--HPSGNY 243
                 T   F   GT +A    D  + +W+  T+ L++     S  + A+ F      N+
Sbjct: 1098 RQKAATMARFSHDGTSLAVV-FDTALTLWNPDTNVLMETLSFGSDPILAVEFGGEKCANF 922

Query: 244  LITASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRT-GEYFASGGSDEQVMVWKSNF 302
            ++  S+ + + +L+      L TL  H       A   T G+   +  +D+ V  ++ N 
Sbjct: 921  VV-FSTPTCVNVLN------LSTLSVHMQVMLRRAILXTDGDLMCAVSADQDVYXFRPNE 763

Query: 303  DIVDYGDMKA 312
            D   +   KA
Sbjct: 762  DKPVFYKKKA 733
>04088
          Length = 511

 Score = 42.4 bits (98), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 30/118 (25%), Positives = 54/118 (45%), Gaps = 3/118 (2%)
 Frame = +3

Query: 187 GGFVTYVDFHPSGTCIAAAGMDNTVKVWDARTHRLLQHYQLHSAAVNALS--FHPSGNYL 244
           G  VT V F   G C   +  DNTV++ D  T  +L  +  H  +   +    +     +
Sbjct: 30  GKAVTSVTFTRDGQCSLVSSQDNTVRLMDKDTGEMLNEFTGHKHSQYKIDSCLNNEDTLV 209

Query: 245 ITASSDSTLKILDLMEGRLLYTL-HGHQGPATTVAFSRTGEYFASGGSDEQVMVWKSN 301
           ++ S D  +   DL+E +L+ TL H    P  +++F        +  +D +V +W+S+
Sbjct: 210 VSGSEDGKVYFWDLVEAKLVDTLDHKTTRPVHSLSFHHAELCLMTACAD-KVFLWRSS 380

 Score = 31.6 bits (70), Expect = 0.59,   Method: Compositional matrix adjust.
 Identities = 35/115 (30%), Positives = 52/115 (45%), Gaps = 5/115 (4%)
 Frame = +3

Query: 21  AVTCVDFSLNTKHLASGSMDSTLMIWHMKSQSRAYRFTGHKDAV----TCVNFSPSGHLL 76
           AVT V F+ + +     S D+T+ +    +      FTGHK +     +C+N   +  L+
Sbjct: 36  AVTSVTFTRDGQCSLVSSQDNTVRLMDKDTGEMLNEFTGHKHSQYKIDSCLNNEDT--LV 209

Query: 77  ASGSRDKTVRIW-VPNVKGESTVFRAHTATVRSVHFCSDGQSLVTASDDKTVKVW 130
            SGS D  V  W +   K   T+    T  V S+ F      L+TA  DK V +W
Sbjct: 210 VSGSEDGKVYFWDLVEAKLVDTLDHKTTRPVHSLSFHHAELCLMTACADK-VFLW 371

 Score = 28.5 bits (62), Expect = 5.2,   Method: Compositional matrix adjust.
 Identities = 20/81 (24%), Positives = 34/81 (41%), Gaps = 2/81 (2%)
 Frame = +3

Query: 63  AVTCVNFSPSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQS--LVT 120
           AVT V F+  G      S+D TVR+   +       F  H  +   +  C + +   +V+
Sbjct: 36  AVTSVTFTRDGQCSLVSSQDNTVRLMDKDTGEMLNEFTGHKHSQYKIDSCLNNEDTLVVS 215

Query: 121 ASDDKTVKVWSTHRQRFLFSL 141
            S+D  V  W     + + +L
Sbjct: 216 GSEDGKVYFWDLVEAKLVDTL 278
>27806
          Length = 419

 Score = 41.2 bits (95), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 21/63 (33%), Positives = 32/63 (50%)
 Frame = -1

Query: 155 PDGRLIVSASDDKTVKLWDKTSRECIHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVW 214
           P   +I +AS D T +++   +  C+ +Y  H G V  V FHP    +  A  D+T  VW
Sbjct: 395 PGHPIIGTASADHTARIYSIETGACVLTYGGHQGSVNAVRFHPGQDLVLTASGDHTAHVW 216

Query: 215 DAR 217
            A+
Sbjct: 215 RAQ 207

 Score = 39.7 bits (91), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 19/59 (32%), Positives = 30/59 (50%)
 Frame = -1

Query: 197 PSGTCIAAAGMDNTVKVWDARTHRLLQHYQLHSAAVNALSFHPSGNYLITASSDSTLKI 255
           P    I  A  D+T +++   T   +  Y  H  +VNA+ FHP  + ++TAS D T  +
Sbjct: 395 PGHPIIGTASADHTARIYSIETGACVLTYGGHQGSVNAVRFHPGQDLVLTASGDHTAHV 219

 Score = 35.4 bits (80), Expect = 0.045,   Method: Compositional matrix adjust.
 Identities = 19/64 (29%), Positives = 28/64 (43%)
 Frame = -1

Query: 239 PSGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGEYFASGGSDEQVMVW 298
           P    + TAS+D T +I  +  G  + T  GHQG    V F    +   +   D    VW
Sbjct: 395 PGHPIIGTASADHTARIYSIETGACVLTYGGHQGSVNAVRFHPGQDLVLTASGDHTAHVW 216

Query: 299 KSNF 302
           ++ F
Sbjct: 215 RAQF 204

 Score = 34.3 bits (77), Expect = 0.086,   Method: Compositional matrix adjust.
 Identities = 15/55 (27%), Positives = 28/55 (50%)
 Frame = -1

Query: 34  LASGSMDSTLMIWHMKSQSRAYRFTGHKDAVTCVNFSPSGHLLASGSRDKTVRIW 88
           + + S D T  I+ +++ +    + GH+ +V  V F P   L+ + S D T  +W
Sbjct: 380 IGTASADHTARIYSIETGACVLTYGGHQGSVNAVRFHPGQDLVLTASGDHTAHVW 216

 Score = 32.3 bits (72), Expect = 0.35,   Method: Compositional matrix adjust.
 Identities = 26/73 (35%), Positives = 35/73 (47%), Gaps = 2/73 (2%)
 Frame = -1

Query: 67  VNFSPSGH-LLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSLV-TASDD 124
           V+ S  GH ++ + S D T RI+          +  H  +V +V F   GQ LV TAS D
Sbjct: 410 VSVSRPGHPIIGTASADHTARIYSIETGACVLTYGGHQGSVNAVRF-HPGQDLVLTASGD 234

Query: 125 KTVKVWSTHRQRF 137
            T  VW   R +F
Sbjct: 233 HTAHVW---RAQF 204
>03044
          Length = 1952

 Score = 41.2 bits (95), Expect = 9e-04,   Method: Compositional matrix adjust.
 Identities = 59/254 (23%), Positives = 102/254 (40%), Gaps = 28/254 (11%)
 Frame = -2

Query: 39   MDSTLMIWHMKSQSRAYRFTGHKDAVTCVNFSPSGHLLASGSRDKTVRIWVPNVKG--ES 96
             DST++  +M     A + +    AVTC   S   + LA    D  V+I+  N     E+
Sbjct: 1837 FDSTVLTGNM-----AEKHSFGVKAVTCHAASGDRNGLALSLNDHEVKIYKKNGSKWQET 1673

Query: 97   TVFRAHTATVRSVHFCSDGQSLVTASDDKTVKVWSTHRQRFLFSLT-QHIN-WVRCAKFS 154
                 H   V  + +      +VT   D+   VW+    ++   L    IN    C K+S
Sbjct: 1672 DTLGEHGQRVTGIDWAPKSNRIVTCGADRNAYVWTYQDGKWQPHLVILRINRAATCVKWS 1493

Query: 155  PDGRLIVSASDDK--TVKLWDKTSRECIHSYCEHG--GFVTYVDFHPSGTCIAAAGMDNT 210
            P+       S  +  +V  +++  R  +  + +      VT +D+HP+   IAA   D  
Sbjct: 1492 PEENKFAVGSSARLISVSYYEEEHRWWVSKHIKKPIRSTVTCLDWHPNNILIAAGSTDFK 1313

Query: 211  VKV----------------WDART--HRLLQHYQLHSAA-VNALSFHPSGNYLITASSDS 251
             +V                W ++     L+  +       V+A+SF PSG  +   + DS
Sbjct: 1312 ARVFSGYVKETEAKPGPNSWGSKMTFAALMAEFSNGGGGWVHAVSFSPSGEKIAWVAHDS 1133

Query: 252  TLKILD-LMEGRLL 264
            ++ + D  M+ RL+
Sbjct: 1132 SVSVGDSTMQNRLV 1091

 Score = 33.9 bits (76), Expect = 0.12,   Method: Compositional matrix adjust.
 Identities = 39/171 (22%), Positives = 60/171 (35%), Gaps = 16/171 (9%)
 Frame = -2

Query: 21   AVTCVDFSLNTKHLASGSMDSTLMIWHMKSQSRAYRFTGH-----KDAVTCVNFSPSGHL 75
            A TCV +S      A GS    + + + + + R +  + H     +  VTC+++ P+  L
Sbjct: 1516 AATCVKWSPEENKFAVGSSARLISVSYYEEEHR-WWVSKHIKKPIRSTVTCLDWHPNNIL 1340

Query: 76   LASGSRDKTVRIWV-----------PNVKGESTVFRAHTATVRSVHFCSDGQSLVTASDD 124
            +A+GS D   R++            PN  G    F A  A      F + G         
Sbjct: 1339 IAAGSTDFKARVFSGYVKETEAKPGPNSWGSKMTFAALMA-----EFSNGGG-------- 1199

Query: 125  KTVKVWSTHRQRFLFSLTQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKT 175
                                  WV    FSP G  I   + D +V + D T
Sbjct: 1198 ---------------------GWVHAVSFSPSGEKIAWVAHDSSVSVGDST 1109
>02948
          Length = 1207

 Score = 40.4 bits (93), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 38/154 (24%), Positives = 60/154 (38%), Gaps = 4/154 (2%)
 Frame = -2

Query: 156 DGRLIVSASDDKTVKLWDKTSRECIHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVW- 214
           +GR I +             SR+      ++    T V  HP+  CIA       +  W 
Sbjct: 849 NGRYIAAVQGCDLTIFSCSKSRKPKKLKAQNNAAFTCVSCHPTDVCIATGHASGKITFWW 670

Query: 215 ---DARTHRLLQHYQLHSAAVNALSFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGHQ 271
                +T   + H+  HS  V  L+F P G+ L++   + TL +   M       L    
Sbjct: 669 NFDQDKTVLSVSHW--HSLPVTCLAFTPEGSCLLSGGHECTL-VRWQMNSEHKEFLPRLG 499

Query: 272 GPATTVAFSRTGEYFASGGSDEQVMVWKSNFDIV 305
            P   +  S  G +F +G SD  + V  S+F I+
Sbjct: 498 APLHNIVVSPDGVFFVTGHSDNVLQVITSSFSIM 397

 Score = 36.2 bits (82), Expect = 0.028,   Method: Compositional matrix adjust.
 Identities = 29/111 (26%), Positives = 46/111 (41%), Gaps = 2/111 (1%)
 Frame = -2

Query: 21  AVTCVDFSLNTKHLASGSMDSTLMIWHMKSQSRAYRFTGHKDA--VTCVNFSPSGHLLAS 78
           A TCV        +A+G     +  W    Q +      H  +  VTC+ F+P G  L S
Sbjct: 750 AFTCVSCHPTDVCIATGHASGKITFWWNFDQDKTVLSVSHWHSLPVTCLAFTPEGSCLLS 571

Query: 79  GSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSLVTASDDKTVKV 129
           G  + T+  W  N + +  + R   A + ++    DG   VT   D  ++V
Sbjct: 570 GGHECTLVRWQMNSEHKEFLPRL-GAPLHNIVVSPDGVFFVTGHSDNVLQV 421

 Score = 30.4 bits (67), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 19/72 (26%), Positives = 31/72 (43%), Gaps = 2/72 (2%)
 Frame = -2

Query: 18  HRDAVTCVDFSLNTKHLASGSMDSTLMIWHMKSQSRAY--RFTGHKDAVTCVNFSPSGHL 75
           H   VTC+ F+     L SG  + TL+ W M S+ + +  R       +     SP G  
Sbjct: 627 HSLPVTCLAFTPEGSCLLSGGHECTLVRWQMNSEHKEFLPRLGAPLHNIV---VSPDGVF 457

Query: 76  LASGSRDKTVRI 87
             +G  D  +++
Sbjct: 456 FVTGHSDNVLQV 421
>26107
          Length = 1338

 Score = 40.4 bits (93), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 62/263 (23%), Positives = 108/263 (41%), Gaps = 60/263 (22%)
 Frame = -3

Query: 15  FKGHRDAVTCVDFSLNT-KHLASGSMDSTLMIWHMK------------------------ 49
           F GH+ +V  V    ++    ASG+ D  +M+W  +                        
Sbjct: 973 FIGHKCSVRSVASCPSSPAQCASGARDGHIMLWDSRVNKKREHQPCSQVHQVCPQSGHQS 794

Query: 50  ---SQSRAYRFTGHK------DAVTCVNFSPSGHLLASGSRDKTVRIW------------ 88
                 R +R  G K       +VTCV +     +++SG+ D  V++W            
Sbjct: 793 KPAKHRRIHRAAGPKGVMDTQQSVTCVLYQTDNLIISSGANDGCVKMWDTRKWYTNTTTS 614

Query: 89  VPNVKGESTVFRAHTATVRS-VHFCSD---GQSLVTASDDKTVK--VWSTHRQRFLFSLT 142
           +P V   +  +  H   ++  V  C D    Q  V+ +D+K  +  +   +R+   +   
Sbjct: 613 LP-VPVHTFDYPGHMRRLKGIVTMCMDPWKSQLFVSYTDNKVYRYQLAGQYREPQEYVYA 437

Query: 143 QHIN---WVRCAKFSPDGRLIVSASDDKTVKLW--DKTSRECIHSYCEHGGFVTYVDFHP 197
            H N   +VRCA  SPDG+ ++S S   T  +W  DK ++  +     H   V+ VD+  
Sbjct: 436 GHRNDTFFVRCA-ISPDGKYLLSGSGRNTGVIWEVDKPNKRPLF-LIGHTEDVSAVDWCS 263

Query: 198 SGTC-IAAAGMDNTVKVW--DAR 217
           +  C +A    D ++++W  DAR
Sbjct: 262 TDVCKLATVSDDRSLRIWRPDAR 194

 Score = 33.5 bits (75), Expect = 0.15,   Method: Compositional matrix adjust.
 Identities = 22/83 (26%), Positives = 39/83 (46%), Gaps = 1/83 (1%)
 Frame = -3

Query: 222  LQHYQLHSAAVNALSFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATTVA-FS 280
            +  +  H+ AV   S+  + +  +TAS D T+ + D+     + T  GH+    +VA   
Sbjct: 1108 VHRWXAHNNAVFDYSWISNDSQCLTASGDQTVALWDVETTTKVTTFIGHKCSVRSVASCP 929

Query: 281  RTGEYFASGGSDEQVMVWKSNFD 303
             +    ASG  D  +M+W S  +
Sbjct: 928  SSPAQCASGARDGHIMLWDSRVN 860

 Score = 32.3 bits (72), Expect = 0.37,   Method: Compositional matrix adjust.
 Identities = 41/182 (22%), Positives = 71/182 (39%), Gaps = 24/182 (13%)
 Frame = -3

Query: 21  AVTCVDFSLNTKHLASGSMDSTLMIWHMKS-----------QSRAYRFTGH----KDAVT 65
           +VTCV +  +   ++SG+ D  + +W  +                + + GH    K  VT
Sbjct: 727 SVTCVLYQTDNLIISSGANDGCVKMWDTRKWYTNTTTSLPVPVHTFDYPGHMRRLKGIVT 548

Query: 66  CVNFSPSGHLLASGSRDKTVRIWVPNVKGESTVF-----RAHTATVRSVHFCSDGQSLVT 120
                    L  S + +K  R  +     E   +     R  T  VR      DG+ L++
Sbjct: 547 MCMDPWKSQLFVSYTDNKVYRYQLAGQYREPQEYVYAGHRNDTFFVRCA-ISPDGKYLLS 371

Query: 121 ASDDKTVKVWS----THRQRFLFSLTQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKTS 176
            S   T  +W       R  FL   T+ ++ V     S D   + + SDD+++++W   +
Sbjct: 370 GSGRNTGVIWEVDKPNKRPLFLIGHTEDVSAVDWC--STDVCKLATVSDDRSLRIWRPDA 197

Query: 177 RE 178
           RE
Sbjct: 196 RE 191
>29912
          Length = 510

 Score = 40.4 bits (93), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 30/118 (25%), Positives = 56/118 (47%), Gaps = 6/118 (5%)
 Frame = +3

Query: 189 FVTYVDFHPSGTCIAAAGMDNTVKVWDARTHRLLQHYQLHSAAVNALSFHPSGNYLITAS 248
           ++  V +   G  +A       V+VWD    + L+    H+A V +LS++   ++++++ 
Sbjct: 15  YIGAVSWIKEGNYLALGTSTGEVQVWDVTQQKKLRTMAGHAARVGSLSWN---SFIVSSG 185

Query: 249 SDST------LKILDLMEGRLLYTLHGHQGPATTVAFSRTGEYFASGGSDEQVMVWKS 300
           S S       +++ D   G    TL GH      + +S  G+Y ASG +D  + VW +
Sbjct: 186 SRSGNIHHHDVRVADHHVG----TLSGHSQEVCGLRWSPDGKYLASGANDNLLCVWPA 347

 Score = 40.4 bits (93), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 37/160 (23%), Positives = 68/160 (42%), Gaps = 15/160 (9%)
 Frame = +3

Query: 106 VRSVHFCSDGQSLVTASDDKTVKVWSTHRQRFLFSLTQHINWVRCAKFSPDGRLIVSASD 165
           + +V +  +G  L   +    V+VW   +Q+ L ++  H    R    S +  ++ S S 
Sbjct: 18  IGAVSWIKEGNYLALGTSTGEVQVWDVTQQKKLRTMAGHA--ARVGSLSWNSFIVSSGSR 191

Query: 166 DKTVKLWD-KTSRECIHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDAR-----TH 219
              +   D + +   + +   H   V  + + P G  +A+   DN + VW A+     + 
Sbjct: 192 SGNIHHHDVRVADHHVGTLSGHSQEVCGLRWSPDGKYLASGANDNLLCVWPAQVTGGNST 371

Query: 220 RLLQHYQLHSAAVNALSFHP---------SGNYLITASSD 250
           + L  +  H AAV AL++ P          G+ LI  SS+
Sbjct: 372 QPLHTFSQHQAAVKALAWCPWQPSXLASGGGDVLIVTSSN 491

 Score = 39.3 bits (90), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 19/61 (31%), Positives = 31/61 (50%), Gaps = 5/61 (8%)
 Frame = +3

Query: 57  FTGHKDAVTCVNFSPSGHLLASGSRDKTVRIWVPNVKGEST-----VFRAHTATVRSVHF 111
            +GH   V  + +SP G  LASG+ D  + +W   V G ++      F  H A V+++ +
Sbjct: 246 LSGHSQEVCGLRWSPDGKYLASGANDNLLCVWPAQVTGGNSTQPLHTFSQHQAAVKALAW 425

Query: 112 C 112
           C
Sbjct: 426 C 428

 Score = 32.0 bits (71), Expect = 0.42,   Method: Compositional matrix adjust.
 Identities = 30/149 (20%), Positives = 62/149 (41%), Gaps = 10/149 (6%)
 Frame = +3

Query: 17  GHRDAVTCVDFSLNTKHLASGSMDSTLMIWHMKSQSRAYRFTGHKDAVTCVNFSPSGHLL 76
           G  + +  V +     +LA G+    + +W +  Q +     GH   V  ++++    ++
Sbjct: 3   GPEEYIGAVSWIKEGNYLALGTSTGEVQVWDVTQQKKLRTMAGHAARVGSLSWNS--FIV 176

Query: 77  ASGSRDKT-----VRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSLVTASDDKTVKVW- 130
           +SGSR        VR+   +V         H+  V  + +  DG+ L + ++D  + VW 
Sbjct: 177 SSGSRSGNIHHHDVRVADHHVG----TLSGHSQEVCGLRWSPDGKYLASGANDNLLCVWP 344

Query: 131 ----STHRQRFLFSLTQHINWVRCAKFSP 155
                 +  + L + +QH   V+   + P
Sbjct: 345 AQVTGGNSTQPLHTFSQHQAAVKALAWCP 431
>01462
          Length = 995

 Score = 40.0 bits (92), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 19/65 (29%), Positives = 36/65 (55%), Gaps = 1/65 (1%)
 Frame = +2

Query: 118 LVTASDDKTVKVWSTHRQRFLFSLTQHINWVRCAKFSPDGRLIVSASDDKTVKLWD-KTS 176
           L   + D+ + VW     ++L ++  H +++       D +  VSAS+D TV++WD ++S
Sbjct: 242 LYAGAGDRKIHVWDIEAGQYLNAMEGHKDYIHKVVMKNDAQECVSASEDGTVRMWDIRSS 421

Query: 177 RECIH 181
            E +H
Sbjct: 422 TETVH 436

 Score = 37.7 bits (86), Expect = 0.009,   Method: Compositional matrix adjust.
 Identities = 19/64 (29%), Positives = 30/64 (46%)
 Frame = +2

Query: 25  VDFSLNTKHLASGSMDSTLMIWHMKSQSRAYRFTGHKDAVTCVNFSPSGHLLASGSRDKT 84
           VD  + T+ L +G+ D  + +W +++        GHKD +  V          S S D T
Sbjct: 215 VDEKMGTRRLYAGAGDRKIHVWDIEAGQYLNAMEGHKDYIHKVVMKNDAQECVSASEDGT 394

Query: 85  VRIW 88
           VR+W
Sbjct: 395 VRMW 406
>38177
          Length = 430

 Score = 39.7 bits (91), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 22/93 (23%), Positives = 42/93 (45%)
 Frame = +3

Query: 66  CVNFSPSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSLVTASDDK 125
           C+ ++P G  L +G+      +W        T+ +AH  +VR++ + +  Q +VTA    
Sbjct: 3   CLAWTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDVSVRAMRWSNHDQWMVTADHSG 182

Query: 126 TVKVWSTHRQRFLFSLTQHINWVRCAKFSPDGR 158
            +K W ++          H   +R  + +P GR
Sbjct: 183 YIKYWQSNMNNVKM-FQGHKEPIRGVRLAPPGR 278
>14500
          Length = 1238

 Score = 39.3 bits (90), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 22/73 (30%), Positives = 34/73 (46%)
 Frame = +3

Query: 16  KGHRDAVTCVDFSLNTKHLASGSMDSTLMIWHMKSQSRAYRFTGHKDAVTCVNFSPSGHL 75
           K HR+ ++   F+ N            L+IW   + SR    TGH   V  +  SP G  
Sbjct: 363 KEHRELISSHGFAQNQ-----------LIIWKYPAMSRVAELTGHTARVLHMAMSPDGET 509

Query: 76  LASGSRDKTVRIW 88
           + S + D+T+R+W
Sbjct: 510 VVSAAADETLRLW 548

 Score = 35.4 bits (80), Expect = 0.037,   Method: Compositional matrix adjust.
 Identities = 18/58 (31%), Positives = 29/58 (50%), Gaps = 5/58 (8%)
 Frame = +2

Query: 57  FTGHKDAVTCVNFSPSGHLLASGSRDKTVRIWVPNVKGEST-----VFRAHTATVRSV 109
            +GH   V  + +SP G  LASG+ D  + +W   V G ++      F  H A V+++
Sbjct: 47  LSGHSQEVCGLRWSPDGKYLASGANDNLLCVWPAQVTGGNSTQPLHTFSQHQAAVKAL 220

 Score = 32.0 bits (71), Expect = 0.50,   Method: Compositional matrix adjust.
 Identities = 16/44 (36%), Positives = 23/44 (52%)
 Frame = +3

Query: 129 VWSTHRQRFLFSLTQHINWVRCAKFSPDGRLIVSASDDKTVKLW 172
           +W       +  LT H   V     SPDG  +VSA+ D+T++LW
Sbjct: 417 IWKYPAMSRVAELTGHTARVLHMAMSPDGETVVSAAADETLRLW 548

 Score = 28.1 bits (61), Expect = 6.8,   Method: Compositional matrix adjust.
 Identities = 17/55 (30%), Positives = 28/55 (50%), Gaps = 5/55 (9%)
 Frame = +2

Query: 15  FKGHRDAVTCVDFSLNTKHLASGSMDSTLMIWHMK-----SQSRAYRFTGHKDAV 64
             GH   V  + +S + K+LASG+ D+ L +W  +     S    + F+ H+ AV
Sbjct: 47  LSGHSQEVCGLRWSPDGKYLASGANDNLLCVWPAQVTGGNSTQPLHTFSQHQAAV 211

 Score = 27.7 bits (60), Expect = 7.8,   Method: Compositional matrix adjust.
 Identities = 13/35 (37%), Positives = 19/35 (54%)
 Frame = +2

Query: 266 TLHGHQGPATTVAFSRTGEYFASGGSDEQVMVWKS 300
           TL GH      + +S  G+Y ASG +D  + VW +
Sbjct: 44  TLSGHSQEVCGLRWSPDGKYLASGANDNLLCVWPA 148
>15972
          Length = 1069

 Score = 38.9 bits (89), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 22/77 (28%), Positives = 40/77 (51%)
 Frame = +3

Query: 228 HSAAVNALSFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGEYFA 287
           H   V  L+ HPSG   +T S D TL++ + M GR+ + +   +  A +V ++  G Y+ 
Sbjct: 234 HKGPVRHLAVHPSGKLTLTVSQDRTLRLWNNMNGRIAF-ISNMKEAAESVRWAPGGLYY- 407

Query: 288 SGGSDEQVMVWKSNFDI 304
                  V+ ++S+ D+
Sbjct: 408 -------VVAFRSHLDV 437

 Score = 34.7 bits (78), Expect = 0.063,   Method: Compositional matrix adjust.
 Identities = 21/65 (32%), Positives = 30/65 (46%)
 Frame = +3

Query: 57  FTGHKDAVTCVNFSPSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQ 116
           F+GHK  V  +   PSG L  + S+D+T+R+W  N+ G             SV +   G 
Sbjct: 225 FSGHKGPVRHLAVHPSGKLTLTVSQDRTLRLW-NNMNGRIAFISNMKEAAESVRWAPGGL 401

Query: 117 SLVTA 121
             V A
Sbjct: 402 YYVVA 416

 Score = 33.9 bits (76), Expect = 0.13,   Method: Compositional matrix adjust.
 Identities = 17/66 (25%), Positives = 31/66 (46%)
 Frame = +3

Query: 182 SYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDARTHRLLQHYQLHSAAVNALSFHPSG 241
           ++  H G V ++  HPSG        D T+++W+    R+     +  AA  ++ + P G
Sbjct: 222 TFSGHKGPVRHLAVHPSGKLTLTVSQDRTLRLWNNMNGRIAFISNMKEAA-ESVRWAPGG 398

Query: 242 NYLITA 247
            Y + A
Sbjct: 399 LYYVVA 416

 Score = 30.4 bits (67), Expect = 1.4,   Method: Compositional matrix adjust.
 Identities = 28/109 (25%), Positives = 45/109 (41%), Gaps = 6/109 (5%)
 Frame = +3

Query: 61  KDAVTCVNFSPSGHLLASGSRDKTVRIWVPNVKGE------STVFRAHTATVRSVHFCSD 114
           K  +TC+ FS +    A       VR+  P V GE         F  H   VR +     
Sbjct: 114 KGTITCLQFS*TRTCSAP------VRMG-PCVCGECPPG*PERTFSGHKGPVRHLAVHPS 272

Query: 115 GQSLVTASDDKTVKVWSTHRQRFLFSLTQHINWVRCAKFSPDGRLIVSA 163
           G+  +T S D+T+++W+    R  F ++         +++P G   V A
Sbjct: 273 GKLTLTVSQDRTLRLWNNMNGRIAF-ISNMKEAAESVRWAPGGLYYVVA 416

 Score = 28.9 bits (63), Expect = 3.9,   Method: Compositional matrix adjust.
 Identities = 32/119 (26%), Positives = 53/119 (44%), Gaps = 2/119 (1%)
 Frame = +3

Query: 12  ERHFKGHRDAVTCVDFSLNTKHLASGSMDSTLMIWHMKSQSRAYRFTGHKDAVTCVNFSP 71
           ER F GH+  V  +    + K   + S D TL +W+  +   A+  +  K+A   V ++P
Sbjct: 216 ERTFSGHKGPVRHLAVHPSGKLTLTVSQDRTLRLWNNMNGRIAF-ISNMKEAAESVRWAP 392

Query: 72  SGHLLASGSRDKTVRIWVPNVKGESTVFRA--HTATVRSVHFCSDGQSLVTASDDKTVK 128
            G       R   + ++    KG   + R+   + TV SV F +D   LV   + K +K
Sbjct: 393 GGLYYVVAFRSH-LDVYSVESKG---LLRSIDTSQTVNSVGFVTD-TVLVYGGEGKVMK 554
>05393
          Length = 904

 Score = 38.5 bits (88), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 43/168 (25%), Positives = 75/168 (44%), Gaps = 11/168 (6%)
 Frame = +1

Query: 72  SGHLLASGSRDKTVRIWVPNVKGESTVFRAHTA---TVRSVHFCSDGQSLVTASDDKTVK 128
           S HLL +GS D TV+  V + +   T  ++ T      ++V    +   L+  +D   V 
Sbjct: 1   SRHLL-TGSFDNTVK--VVDCRSAETCHKSWTVEGEVEKAVWNHHNPLQLLACTDKGMVY 171

Query: 129 VWSTHRQRFLFSLTQHINWVR--CAKFSPDGRLIVSASDDKTVKLWDKTSRECIHSYCEH 186
            +    ++ +FS+  H + V   C      G L+++ S+DKT+K+WD    +  H +  +
Sbjct: 172 CFDIRHEKPVFSVGAHSSCVTGVCLSSQIPG-LMITTSEDKTMKVWDIQDDKPTHVFSRN 348

Query: 187 GGFVTYVDFHPSGTC------IAAAGMDNTVKVWDARTHRLLQHYQLH 228
              +   + H +G C       A  G     KVWD R    ++H  L+
Sbjct: 349 ---LKMKELHCTGCCPEAPFVFAVGGGRREPKVWDIRESAAVRHQFLN 483
>30176
          Length = 365

 Score = 37.4 bits (85), Expect = 0.012,   Method: Composition-based stats.
 Identities = 15/37 (40%), Positives = 24/37 (64%)
 Frame = +2

Query: 97  TVFRAHTATVRSVHFCSDGQSLVTASDDKTVKVWSTH 133
           T  ++HT+TV ++ F   G  L + SDDKT+K+W  +
Sbjct: 2   TTLKSHTSTVWNLTFDKTGTRLASCSDDKTIKIWQEY 112

 Score = 29.6 bits (65), Expect = 2.1,   Method: Composition-based stats.
 Identities = 22/85 (25%), Positives = 33/85 (38%), Gaps = 17/85 (20%)
 Frame = +2

Query: 140 SLTQHINWVRCAKFSPDGRLIVSASDDKTVKLWD------------KTSRECIHSYCEHG 187
           +L  H + V    F   G  + S SDDKT+K+W             K +       C  G
Sbjct: 5   TLKSHTSTVWNLTFDKTGTRLASCSDDKTIKIWQEYLPGNPEGIVTKDNEPTWKCVCTLG 184

Query: 188 GFVTYVDF-----HPSGTCIAAAGM 207
           G+ +   +     H +G  + A GM
Sbjct: 185 GYTSRALYDIDWSHLTGDIVTAGGM 259

 Score = 28.1 bits (61), Expect = 6.3,   Method: Composition-based stats.
 Identities = 13/29 (44%), Positives = 17/29 (58%)
 Frame = +2

Query: 60 HKDAVTCVNFSPSGHLLASGSRDKTVRIW 88
          H   V  + F  +G  LAS S DKT++IW
Sbjct: 17 HTSTVWNLTFDKTGTRLASCSDDKTIKIW 103
>31118
          Length = 390

 Score = 35.8 bits (81), Expect = 0.036,   Method: Compositional matrix adjust.
 Identities = 15/31 (48%), Positives = 21/31 (67%)
 Frame = -2

Query: 228 HSAAVNALSFHPSGNYLITASSDSTLKILDL 258
           HSA +  + F PS  Y++T S DST+K+ DL
Sbjct: 383 HSAEIRCIRFSPSAYYMLTCSYDSTIKLTDL 291

 Score = 30.0 bits (66), Expect = 1.9,   Method: Compositional matrix adjust.
 Identities = 11/26 (42%), Positives = 17/26 (65%)
 Frame = -2

Query: 148 VRCAKFSPDGRLIVSASDDKTVKLWD 173
           +RC +FSP    +++ S D T+KL D
Sbjct: 371 IRCIRFSPSAYYMLTCSYDSTIKLTD 294
>06576
          Length = 1547

 Score = 35.4 bits (80), Expect = 0.037,   Method: Compositional matrix adjust.
 Identities = 38/159 (23%), Positives = 70/159 (44%), Gaps = 16/159 (10%)
 Frame = -2

Query: 21   AVTCVDFSLNT------KHL--ASGSMDSTLMIW--HMKSQSRAYRFTGHKDAVTCVNFS 70
             V+C+ +S +T      KHL  A+   D ++ ++   +K+ ++ +   GH D V  V FS
Sbjct: 1234 GVSCLAWSPSTSLSSLDKHLCFAAACDDHSVRVFTSDLKTTNKTHVVKGHTDFVNSVTFS 1055

Query: 71   PSGH-LLASGSRDKTVRIWV-----PNVKGESTVFRAHTATVRSVHFCSDGQSLVTASDD 124
            P+    + S   D T R+W          GES +FR     +       +   L+    D
Sbjct: 1054 PTEEDQVXSTGDDLTCRVWTGKDGQDGRYGESVIFRLTAPGMAVCWHADEPLKLMVGQKD 875

Query: 125  KTVKVWSTHRQRFLFSLTQHINWVRCAKFSPDGRLIVSA 163
              ++ +S   Q+ + SL+  ++ +    +S    L+V A
Sbjct: 874  GIIRFFSLSNQQPIMSLSCGVSPLLDCDWSKHNCLLVGA 758
>34005
          Length = 456

 Score = 34.7 bits (78), Expect = 0.063,   Method: Compositional matrix adjust.
 Identities = 30/122 (24%), Positives = 47/122 (38%), Gaps = 7/122 (5%)
 Frame = +1

Query: 121 ASDDKTVKVWSTHRQRFLFSLTQHINWVRCA-KFSPDGRLIVSASDDKTVKLWDKT---S 176
           A+   T   W   R  F     Q +    C   +SPD   + S S+D +V +WD T    
Sbjct: 49  ATSTTTTYAWRATRWGFCPLTPQEV----CGLSWSPDATFLASGSNDNSVNIWDSTLGMD 216

Query: 177 RECIHSYCEHGGFVTYVDFHPSGTCIAAAG---MDNTVKVWDARTHRLLQHYQLHSAAVN 233
              +H+   H   V  V + P  T + A G    D  ++ W+  T   ++     S   +
Sbjct: 217 VPPLHTLTSHQAAVKAVAWCPWQTRMLATGGGTNDRHIRFWNTNTGACVKAVDTQSQVCS 396

Query: 234 AL 235
            L
Sbjct: 397 VL 402

 Score = 33.9 bits (76), Expect = 0.13,   Method: Compositional matrix adjust.
 Identities = 22/80 (27%), Positives = 40/80 (50%), Gaps = 10/80 (12%)
 Frame = +1

Query: 64  VTCVNFSPSGHLLASGSRDKTVRIW-------VPNVKGESTVFRAHTATVRSVHFCSDGQ 116
           V  +++SP    LASGS D +V IW       VP +        +H A V++V +C    
Sbjct: 121 VCGLSWSPDATFLASGSNDNSVNIWDSTLGMDVPPLH----TLTSHQAAVKAVAWCPWQT 288

Query: 117 SLVT---ASDDKTVKVWSTH 133
            ++     ++D+ ++ W+T+
Sbjct: 289 RMLATGGGTNDRHIRFWNTN 348

 Score = 30.4 bits (67), Expect = 1.4,   Method: Compositional matrix adjust.
 Identities = 30/106 (28%), Positives = 49/106 (46%), Gaps = 6/106 (5%)
 Frame = +1

Query: 22  VTCVDFSLNTKHLASGSMDSTLMIWHMK---SQSRAYRFTGHKDAVTCVNFSP-SGHLLA 77
           V  + +S +   LASGS D+++ IW           +  T H+ AV  V + P    +LA
Sbjct: 121 VCGLSWSPDATFLASGSNDNSVNIWDSTLGMDVPPLHTLTSHQAAVKAVAWCPWQTRMLA 300

Query: 78  S--GSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSLVTA 121
           +  G+ D+ +R W  N  G         + V SV +C + + LV+ 
Sbjct: 301 TGGGTNDRHIRFWNTNT-GACVKAVDTQSQVCSVLWCKEHRELVSG 435
>10264
          Length = 416

 Score = 34.7 bits (78), Expect = 0.072,   Method: Compositional matrix adjust.
 Identities = 24/80 (30%), Positives = 37/80 (46%), Gaps = 2/80 (2%)
 Frame = -1

Query: 222 LQHYQLHSAAVNALSFHPSGNY-LITASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFS 280
           L+    HS  V  +S+ P  +  L++   D+   + D+ +G  L    GH G   T  FS
Sbjct: 266 LRELSGHSQRVTDMSWSPHHDARLVSVGYDAEAFVWDVQKGTALAQFKGHMGRLLTCQFS 87

Query: 281 RTG-EYFASGGSDEQVMVWK 299
               +   +GGSD  V VW+
Sbjct: 86  GLDPDLVMTGGSDASVHVWR 27

 Score = 31.2 bits (69), Expect = 0.75,   Method: Compositional matrix adjust.
 Identities = 22/80 (27%), Positives = 34/80 (42%), Gaps = 4/80 (5%)
 Frame = -1

Query: 13  RHFKGHRDAVTCVDFSLNTKH---LASGSMDSTLMIWHMKSQSRAYRFTGHKDAVTCVNF 69
           R   GH   VT  D S +  H   L S   D+   +W ++  +   +F GH   +    F
Sbjct: 263 RELSGHSQRVT--DMSWSPHHDARLVSVGYDAEAFVWDVQKGTALAQFKGHMGRLLTCQF 90

Query: 70  SP-SGHLLASGSRDKTVRIW 88
           S     L+ +G  D +V +W
Sbjct: 89  SGLDPDLVMTGGSDASVHVW 30
>07665
          Length = 435

 Score = 34.7 bits (78), Expect = 0.072,   Method: Compositional matrix adjust.
 Identities = 27/112 (24%), Positives = 46/112 (41%), Gaps = 9/112 (8%)
 Frame = -2

Query: 28  SLNTKHLASGSMDSTLMIWHMKSQSRAYRFTGHKDAVTCVNFSPSGHLLASGSRDKTVRI 87
           SL   H + G        W +      Y    H D +  + FSP+ + L   +   +++I
Sbjct: 422 SLQPNHCSCG--------WDLNDGKNLYTLE-HNDIINALCFSPNRYWLCV-AYGPSIKI 273

Query: 88  W-------VPNVKGE--STVFRAHTATVRSVHFCSDGQSLVTASDDKTVKVW 130
           W       V  ++ E  S   +A      S+ + +DGQ+L     D T++VW
Sbjct: 272 WDLACKKTVEELRPEVVSPTSKAEQPQCLSLAWSTDGQTLFAGYSDNTIRVW 117
>20662
          Length = 1220

 Score = 34.7 bits (78), Expect = 0.079,   Method: Compositional matrix adjust.
 Identities = 25/112 (22%), Positives = 47/112 (41%), Gaps = 5/112 (4%)
 Frame = +2

Query: 114 DGQSLVTASDDKTVKVWSTHRQRFLFSL----TQHINWVRCAKFSPDGRLIVSASDDKTV 169
           D   ++   D   V +W    +  +FS+     +H +       + D    +SAS D  +
Sbjct: 281 DSHKVLVGLDTGGVALWELQDEDKMFSMLSSACEHDDMTASVSINSDXSHYLSASYDHGI 460

Query: 170 KLWDKTSRECIHSYCEHGGFVTYVDFHPSGTCI-AAAGMDNTVKVWDARTHR 220
           K+W+ T    +++Y  H   V  V  HP+   +  +   D  + +WD R  +
Sbjct: 461 KVWN-TDLTSLYTYRAHSDIVWDVQCHPTEPALFLSCSQDGKIVLWDVRESK 613

 Score = 33.1 bits (74), Expect = 0.19,   Method: Compositional matrix adjust.
 Identities = 27/112 (24%), Positives = 47/112 (41%), Gaps = 5/112 (4%)
 Frame = +2

Query: 156 DGRLIVSASDDKTVKLWDKTSRE----CIHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTV 211
           D   ++   D   V LW+    +     + S CEH      V  +   +   +A  D+ +
Sbjct: 281 DSHKVLVGLDTGGVALWELQDEDKMFSMLSSACEHDDMTASVSINSDXSHYLSASYDHGI 460

Query: 212 KVWDARTHRLLQHYQLHSAAVNALSFHPSGNYL-ITASSDSTLKILDLMEGR 262
           KVW+     L   Y+ HS  V  +  HP+   L ++ S D  + + D+ E +
Sbjct: 461 KVWNTDLTSLYT-YRAHSDIVWDVQCHPTEPALFLSCSQDGKIVLWDVRESK 613
>36111
          Length = 687

 Score = 34.3 bits (77), Expect = 0.091,   Method: Compositional matrix adjust.
 Identities = 19/60 (31%), Positives = 27/60 (45%)
 Frame = +2

Query: 190 VTYVDFHPSGTCIAAAGMDNTVKVWDARTHRLLQHYQLHSAAVNALSFHPSGNYLITASS 249
           V  V FH      A  G D  V +WD    + L  +  +  ++ +L+F   GN L  ASS
Sbjct: 239 VNAVAFHNVYNTFATGGSDGYVNIWDGFHKKRLCXFHRYPTSIASLAFSHDGNVLAIASS 418

 Score = 33.1 bits (74), Expect = 0.18,   Method: Compositional matrix adjust.
 Identities = 21/75 (28%), Positives = 31/75 (41%)
 Frame = +2

Query: 217 RTHRLLQHYQLHSAAVNALSFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATT 276
           + HR+ +        VNA++FH   N   T  SD  + I D    + L   H +     +
Sbjct: 194 KCHRIKEDSLEKIYPVNAVAFHNVYNTFATGGSDGYVNIWDGFHKKRLCXFHRYPTSIAS 373

Query: 277 VAFSRTGEYFASGGS 291
           +AFS  G   A   S
Sbjct: 374 LAFSHDGNVLAIASS 418

 Score = 29.3 bits (64), Expect = 3.3,   Method: Compositional matrix adjust.
 Identities = 12/26 (46%), Positives = 14/26 (53%)
 Frame = +2

Query: 273 PATTVAFSRTGEYFASGGSDEQVMVW 298
           P   VAF      FA+GGSD  V +W
Sbjct: 236 PVNAVAFHNVYNTFATGGSDGYVNIW 313
>11915
          Length = 737

 Score = 33.9 bits (76), Expect = 0.12,   Method: Compositional matrix adjust.
 Identities = 25/93 (26%), Positives = 41/93 (44%), Gaps = 4/93 (4%)
 Frame = +1

Query: 75  LLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQ-SLVTASDDKTVKVWSTH 133
           +LA+G     +++W             H ATV  +HF +D    L++AS D TVK+W   
Sbjct: 448 VLATGHVSGRIKLWNCETGKLLIEMMDHKATVHDLHFAADNSLCLMSASHDGTVKLWEFD 627

Query: 134 RQ---RFLFSLTQHINWVRCAKFSPDGRLIVSA 163
            Q       +L  +       ++S D R + +A
Sbjct: 628 DQGDCNMYLTLRTNAKHAFSCRWSHDRRYVATA 726

 Score = 32.3 bits (72), Expect = 0.32,   Method: Compositional matrix adjust.
 Identities = 21/64 (32%), Positives = 34/64 (53%), Gaps = 3/64 (4%)
 Frame = +1

Query: 113 SDGQSLVTASDDKT--VKVWSTHRQRFLFSLTQHINWVRCAKFSPDGRL-IVSASDDKTV 169
           +D  +LV A+   +  +K+W+    + L  +  H   V    F+ D  L ++SAS D TV
Sbjct: 430 NDSSTLVLATGHVSGRIKLWNCETGKLLIEMMDHKATVHDLHFAADNSLCLMSASHDGTV 609

Query: 170 KLWD 173
           KLW+
Sbjct: 610 KLWE 621
>27270
          Length = 1078

 Score = 33.5 bits (75), Expect = 0.14,   Method: Compositional matrix adjust.
 Identities = 25/94 (26%), Positives = 43/94 (45%), Gaps = 3/94 (3%)
 Frame = +2

Query: 16  KGHRDAVTCVDFSLNTKHLASGSMDSTLMIWHMKSQSRAYRF---TGHKDAVTCVNFSPS 72
           KGH  AVT + +  + + L S S+D  ++ W++ +     ++   +G    V CV    S
Sbjct: 263 KGHSKAVTDMCWRADGRTLYSSSLDGHVIGWNVNTLHMIEKWKATSGRHHGVHCVCLCSS 442

Query: 73  GHLLASGSRDKTVRIWVPNVKGESTVFRAHTATV 106
             LL +   D T+++W    K     F  H+  V
Sbjct: 443 SRLLTA---DHTIKMWDLTTKNVLQEFSGHSTEV 535

 Score = 33.1 bits (74), Expect = 0.19,   Method: Compositional matrix adjust.
 Identities = 34/117 (29%), Positives = 54/117 (46%), Gaps = 6/117 (5%)
 Frame = +2

Query: 34  LASGSMDSTLMIWHMKSQSRAYRFT-GHKDAVTCVNFSPSGHLLASGSRDKTVRIWVPNV 92
           +A GS D ++ ++ +++ +  +    GH  AVT + +   G  L S S D  V  W  N 
Sbjct: 188 VAVGSADGSVGLYSVETHTYTHMLNKGHSKAVTDMCWRADGRTLYSSSLDGHVIGWNVNT 367

Query: 93  -----KGESTVFRAHTATVRSVHFCSDGQSLVTASDDKTVKVWSTHRQRFLFSLTQH 144
                K ++T  R H   V  V  CS  + L+TA  D T+K+W    +  L   + H
Sbjct: 368 LHMIEKWKATSGRHHG--VHCVCLCSSSR-LLTA--DHTIKMWDLTTKNVLQEFSGH 523

 Score = 32.3 bits (72), Expect = 0.33,   Method: Compositional matrix adjust.
 Identities = 34/127 (26%), Positives = 53/127 (41%), Gaps = 4/127 (3%)
 Frame = +2

Query: 113 SDGQSLVTASDDKTVKVWSTHRQRFLFSLTQ-HINWVRCAKFSPDGRLIVSASDDKTVKL 171
           +D   +   S D +V ++S     +   L + H   V    +  DGR + S+S D  V  
Sbjct: 173 ADSAVVAVGSADGSVGLYSVETHTYTHMLNKGHSKAVTDMCWRADGRTLYSSSLDGHVIG 352

Query: 172 WDKTSRECIHSYCEHGG---FVTYVDFHPSGTCIAAAGMDNTVKVWDARTHRLLQHYQLH 228
           W+  +   I  +    G    V  V    S   + A   D+T+K+WD  T  +LQ +  H
Sbjct: 353 WNVNTLHMIEKWKATSGRHHGVHCVCLCSSSRLLTA---DHTIKMWDLTTKNVLQEFSGH 523

Query: 229 SAAVNAL 235
           S  V  L
Sbjct: 524 STEVIKL 544
>13509
          Length = 572

 Score = 33.1 bits (74), Expect = 0.20,   Method: Compositional matrix adjust.
 Identities = 22/61 (36%), Positives = 24/61 (39%)
 Frame = +2

Query: 231 AVNALSFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGEYFASGG 290
           AVN +SFHP    L T  SD      D      L T      P TT  F+  G  FA   
Sbjct: 365 AVNDISFHPVHGTLSTVGSDGRFSFWDKDARTKLKTSEQFDQPITTCNFNAQGNIFAYAS 544

Query: 291 S 291
           S
Sbjct: 545 S 547

 Score = 29.3 bits (64), Expect = 3.0,   Method: Compositional matrix adjust.
 Identities = 15/60 (25%), Positives = 23/60 (38%)
 Frame = +2

Query: 190 VTYVDFHPSGTCIAAAGMDNTVKVWDARTHRLLQHYQLHSAAVNALSFHPSGNYLITASS 249
           V  + FHP    ++  G D     WD      L+  +     +   +F+  GN    ASS
Sbjct: 368 VNDISFHPVHGTLSTVGSDGRFSFWDKDARTKLKTSEQFDQPITTCNFNAQGNIFAYASS 547
>31054
          Length = 392

 Score = 33.1 bits (74), Expect = 0.22,   Method: Compositional matrix adjust.
 Identities = 19/79 (24%), Positives = 34/79 (43%)
 Frame = -2

Query: 197 PSGTCIAAAGMDNTVKVWDARTHRLLQHYQLHSAAVNALSFHPSGNYLITASSDSTLKIL 256
           PS     A G  + VK W       +Q+   H+A +N L+ +  G  L++ + + T+ + 
Sbjct: 385 PSKAVHFAXGSPDXVKQWKFPDGNFIQNLSGHNAIINTLAVNSDG-VLVSGADNGTMHLW 209

Query: 257 DLMEGRLLYTLHGHQGPAT 275
           D   G     +H    P +
Sbjct: 208 DWRTGYNFQRIHAAVQPGS 152
>30297
          Length = 822

 Score = 32.7 bits (73), Expect = 0.26,   Method: Compositional matrix adjust.
 Identities = 12/46 (26%), Positives = 26/46 (56%)
 Frame = -1

Query: 1   MAAPSQEDPSLERHFKGHRDAVTCVDFSLNTKHLASGSMDSTLMIW 46
           +  P  + P + + ++GH ++V+C+D     K L + + D T+ +W
Sbjct: 282 LETPETDSPDVIQSWRGHVESVSCLDLVEQNKVLLTSAADCTVRMW 145

 Score = 27.7 bits (60), Expect = 8.3,   Method: Compositional matrix adjust.
 Identities = 10/32 (31%), Positives = 20/32 (62%)
 Frame = -1

Query: 57  FTGHKDAVTCVNFSPSGHLLASGSRDKTVRIW 88
           + GH ++V+C++      +L + + D TVR+W
Sbjct: 240 WRGHVESVSCLDLVEQNKVLLTSAADCTVRMW 145
>04358
          Length = 2430

 Score = 32.7 bits (73), Expect = 0.30,   Method: Compositional matrix adjust.
 Identities = 60/277 (21%), Positives = 102/277 (36%), Gaps = 32/277 (11%)
 Frame = +1

Query: 57   FTGHKDAVTCVNFSPSG-HLLASGSRDKTVRIWVP--NVKGESTVFRAHTATVRSVHFCS 113
             TGH D ++ + F  +   L+ + S D TVRIW P  +V  E   F     T  SV  C 
Sbjct: 1408 LTGHDDVISSIRFLHTDPGLIMTASHDHTVRIWDPRASVSKEVQRFSGEQNTKCSVLSCD 1587

Query: 114  DGQS-------LVTASDDKTVKVWSTHRQRFLFSLTQ-HINWVRCAKFSPDG-RLIVSAS 164
               S          ++DD  +  W   + + L      H + +    F P   + +++ S
Sbjct: 1588 VNISDRVLCAGTEMSNDDAYLLFWDRRKDKLLGCYEDSHHDDITQVHFGPTSEKTLLTGS 1767

Query: 165  DDKTVKLWD---KTSRECIHSYCEHGGFVTYVDF-HPSGTCIAAAGMDNTVKVWDARTHR 220
             D  V ++D    T  + + S       V    +  P    + A     +  VWD     
Sbjct: 1768 TDGLVNVFDVMQTTEDDALMSTYNTEATVERAGWCGPQSQQVYAITHMLSWHVWDTEKDE 1947

Query: 221  -------LLQHYQLHSAAVNALSFHPSGN-----YLITASSDSTLKILDLM---EGRLLY 265
                   L Q  Q    A   +   P+        L+  +    L +LDL    E +++ 
Sbjct: 1948 DVQQLTDLEQKLQGQCQADYLVDCIPANQSTSPPCLVAGTHTGDLHVLDLSDLEEVKVVR 2127

Query: 266  TLH-GHQGPATTVAFSRTGEYFASGGSDEQVMVWKSN 301
            +L  GH      + + +  +   +GG D  + +W S+
Sbjct: 2128 SLSGGHTDTVRCLHWDKQTQTLVTGGEDSMLCLWSSD 2238
>04395
          Length = 1145

 Score = 32.0 bits (71), Expect = 0.46,   Method: Compositional matrix adjust.
 Identities = 23/64 (35%), Positives = 31/64 (48%), Gaps = 3/64 (4%)
 Frame = +3

Query: 193 VDFHPSGTCIAAAG-MDNTVKVWDARTHRL-LQHYQLHSAAVNALSFHPSGN-YLITASS 249
           VD HP    I A G  D T+ VWD R HR  +     H +++  + FH     +L T S 
Sbjct: 492 VDKHPGQLHIVATGSQDGTLTVWDLRHHRFPMTTLDAHHSSMWEVRFHQQHTPHLFTCSE 671

Query: 250 DSTL 253
           D +L
Sbjct: 672 DGSL 683
>07542
          Length = 1027

 Score = 32.0 bits (71), Expect = 0.51,   Method: Compositional matrix adjust.
 Identities = 17/50 (34%), Positives = 24/50 (48%), Gaps = 1/50 (2%)
 Frame = +1

Query: 250 DSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGEY-FASGGSDEQVMVW 298
           +  + I D+  G L     G  G  T VAFS+ G Y FA G  D ++  +
Sbjct: 7   NGDVAIYDVPHGGLTAVFEGQPGGITHVAFSKDGNYLFAGGRKDPEINCF 156
>20271
          Length = 567

 Score = 32.0 bits (71), Expect = 0.52,   Method: Compositional matrix adjust.
 Identities = 15/48 (31%), Positives = 27/48 (56%)
 Frame = -1

Query: 118 LVTASDDKTVKVWSTHRQRFLFSLTQHINWVRCAKFSPDGRLIVSASD 165
            +TAS D TVK+W+   Q+++ S   + ++V   ++SP    + S  D
Sbjct: 222 FLTASFDWTVKLWNIKEQKYVCSFEDNSDYVSDVQWSPTNPALFSCVD 79

 Score = 27.7 bits (60), Expect = 7.9,   Method: Compositional matrix adjust.
 Identities = 17/58 (29%), Positives = 32/58 (55%), Gaps = 4/58 (6%)
 Frame = -1

Query: 153 FSPDGRLIVSASDDKTVKLWDKTSRECIHSYCEHGGFVTYVDFHPSG----TCIAAAG 206
           FSP     ++AS D TVKLW+   ++ + S+ ++  +V+ V + P+     +C+   G
Sbjct: 234 FSP---FFLTASFDWTVKLWNIKEQKYVCSFEDNSDYVSDVQWSPTNPALFSCVDIMG 70
>27475
          Length = 369

 Score = 31.6 bits (70), Expect = 0.65,   Method: Compositional matrix adjust.
 Identities = 15/33 (45%), Positives = 21/33 (63%), Gaps = 1/33 (3%)
 Frame = +2

Query: 57 FTGHKDAVTCVNFSPS-GHLLASGSRDKTVRIW 88
          FT H   VT V++SP+  HL  SGS D  +++W
Sbjct: 56 FTSHTGWVTGVDWSPTREHLFLSGSYDNVLKLW 154
>35695
          Length = 1651

 Score = 31.2 bits (69), Expect = 0.69,   Method: Compositional matrix adjust.
 Identities = 36/136 (26%), Positives = 59/136 (43%), Gaps = 7/136 (5%)
 Frame = -1

Query: 125  KTVKVWSTHRQRFLFSLTQHINWVRCAKFSPDG-RLIVSASDDKTVKLW--DKTSRECIH 181
            K + VW   +   + +L  H   +        G  +++S+S DKT+ +W  DK   E +H
Sbjct: 1645 KNLYVWDVKQGNMVKTLDAHFGRIIALTSVTVGCNMVISSSIDKTINVWNFDKILEE-VH 1469

Query: 182  SYCEHGGFVTYVDFHPSGT-CIAAAGMDNTVKVWDARTHRLLQHYQLHSAAVNALS---F 237
                    +  V    S + C+A     N   VWD  T RL++   + S+  N +S    
Sbjct: 1468 PLDRMERPIETVHMAASSSLCVATT--RNQTSVWDLETGRLVK-VLVGSSRSNXVSQAFI 1298

Query: 238  HPSGNYLITASSDSTL 253
               G +++TA S S L
Sbjct: 1297 TREGTHVLTAESPSLL 1250
>34511
          Length = 1037

 Score = 31.2 bits (69), Expect = 0.75,   Method: Compositional matrix adjust.
 Identities = 12/36 (33%), Positives = 22/36 (61%)
 Frame = +3

Query: 53 RAYRFTGHKDAVTCVNFSPSGHLLASGSRDKTVRIW 88
          R+    GH + V+C+  + +G  +A+GS D  +R+W
Sbjct: 48 RSGILAGHDNRVSCLGVTENGMSVATGSWDSFLRVW 155

 Score = 29.6 bits (65), Expect = 2.3,   Method: Compositional matrix adjust.
 Identities = 12/33 (36%), Positives = 20/33 (60%)
 Frame = +3

Query: 15 FKGHRDAVTCVDFSLNTKHLASGSMDSTLMIWH 47
            GH + V+C+  + N   +A+GS DS L +W+
Sbjct: 60 LAGHDNRVSCLGVTENGMSVATGSWDSFLRVWN 158
>25880
          Length = 423

 Score = 31.2 bits (69), Expect = 0.84,   Method: Compositional matrix adjust.
 Identities = 21/82 (25%), Positives = 40/82 (48%), Gaps = 1/82 (1%)
 Frame = +2

Query: 12  ERHFKGHRDAVTCVDFSLNTKHLASGSMDSTLMIWHMKS-QSRAYRFTGHKDAVTCVNFS 70
           E H   H+  V  V F  +++++ +GS +  + +++++   +    + GH  A+      
Sbjct: 35  EIHSFQHKHIVKSVAFDNSSENIVTGSNEKLVRVFNLEQPDAEPELYGGHTGAIKRA--- 205

Query: 71  PSGHLLASGSRDKTVRIWVPNV 92
               L ASGS D T+R+W   V
Sbjct: 206 ----LYASGSEDGTLRLWQTTV 259
>20615
          Length = 641

 Score = 30.8 bits (68), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 18/37 (48%), Positives = 23/37 (62%), Gaps = 1/37 (2%)
 Frame = +1

Query: 187 GGFVTYVDFHPSGTCIAAAGMDNTVKVWD-ARTHRLL 222
           GG+V  V F PSG  IA  G D++V V D A  +RL+
Sbjct: 163 GGWVHSVSFSPSGERIAWVGHDSSVSVADSANENRLV 273
>07781
          Length = 1269

 Score = 30.4 bits (67), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 24/73 (32%), Positives = 35/73 (47%), Gaps = 5/73 (6%)
 Frame = -2

Query: 20  DAVTCVDFSLNTKHLASGSMDSTLMIWHMKSQSRAY----RFTGHKDAVTCVNFSPS-GH 74
           +A  C     NT+ + SGS D  L +W ++  +       RFT     VT +   P   H
Sbjct: 788 EAWICAFDQWNTELIYSGSDDCKLKVWDLRVGTTPVLTNSRFTM---GVTSIQSCPQREH 618

Query: 75  LLASGSRDKTVRI 87
           LLA GS D+ +R+
Sbjct: 617 LLAVGSYDENLRL 579
>04524
          Length = 1340

 Score = 30.4 bits (67), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 21/80 (26%), Positives = 35/80 (43%), Gaps = 1/80 (1%)
 Frame = -1

Query: 17   GHRDAVTCVDFSLNTKHLASGSMDSTLMIWHMKSQSRAYRFT-GHKDAVTCVNFSPSGHL 75
            GH   V  V  +    H+ +   D  + +    +    + +  GH   V C+ +     +
Sbjct: 1034 GHLSMVLDVCLTGREGHVVTCDRDEKIRVSQFPNAYNIHTYCLGHTQFVNCLVYVEEFRV 855

Query: 76   LASGSRDKTVRIWVPNVKGE 95
            L SGS D TVR W  N++G+
Sbjct: 854  LISGSGDCTVRAW--NMEGK 801

 Score = 30.4 bits (67), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 21/81 (25%), Positives = 37/81 (45%), Gaps = 1/81 (1%)
 Frame = -1

Query: 73  GHLLASGSRDKTVRI-WVPNVKGESTVFRAHTATVRSVHFCSDGQSLVTASDDKTVKVWS 131
           GH++ +  RD+ +R+   PN     T    HT  V  + +  + + L++ S D TV+ W+
Sbjct: 989 GHVV-TCDRDEKIRVSQFPNAYNIHTYCLGHTQFVNCLVYVEEFRVLISGSGDCTVRAWN 813

Query: 132 THRQRFLFSLTQHINWVRCAK 152
              ++           V CAK
Sbjct: 812 MEGKQLCL--------VHCAK 774
>07151
          Length = 512

 Score = 29.6 bits (65), Expect = 2.2,   Method: Compositional matrix adjust.
 Identities = 10/26 (38%), Positives = 17/26 (65%)
 Frame = -1

Query: 148 VRCAKFSPDGRLIVSASDDKTVKLWD 173
           V+C  FS D  +IV+   D+ ++LW+
Sbjct: 155 VKCFDFSKDKNIIVTGGMDRIIRLWN 78

 Score = 28.9 bits (63), Expect = 4.0,   Method: Compositional matrix adjust.
 Identities = 16/60 (26%), Positives = 28/60 (46%), Gaps = 1/60 (1%)
 Frame = -1

Query: 6   QEDPSLERHFKGHRDAVTCVDFSLNTKHLASGSMDSTLMIWH-MKSQSRAYRFTGHKDAV 64
           + D ++ + +KG    V C DFS +   + +G MD  + +W+   SQ       GH   +
Sbjct: 191 EADQAVFKVYKG----VKCFDFSKDKNIIVTGGMDRIIRLWNPYVSQKPTAMLRGHNAPI 24
>30108
          Length = 1032

 Score = 29.3 bits (64), Expect = 2.7,   Method: Compositional matrix adjust.
 Identities = 20/73 (27%), Positives = 30/73 (41%), Gaps = 1/73 (1%)
 Frame = +1

Query: 144 HINWVRCAKFSPDGRLIVSASD-DKTVKLWDKTSRECIHSYCEHGGFVTYVDFHPSGTCI 202
           H+ W+      P   +++SAS  D  V  W      C       GG V+ +   P G+ +
Sbjct: 394 HLAWL------PSANILLSASPVDTAVMAWSVGGEACTALRYLGGGGVSLLACSPDGSKV 555

Query: 203 AAAGMDNTVKVWD 215
            AA      +VWD
Sbjct: 556 MAATPATLFRVWD 594
>18320
          Length = 450

 Score = 28.9 bits (63), Expect = 4.0,   Method: Compositional matrix adjust.
 Identities = 24/79 (30%), Positives = 37/79 (46%), Gaps = 11/79 (13%)
 Frame = -2

Query: 63  AVTCVNFSPSGHLLASGSRDKTVRIW--------VPNVKGE---STVFRAHTATVRSVHF 111
           AV  V+   +G LLA+GSRD+ + +          P  K +     + +AH+  +  +  
Sbjct: 278 AVDVVHLMQNGQLLAAGSRDRYLTLLDLTKYDPARPKSKKDMQLHCIDKAHSGWIWCM-- 105

Query: 112 CSDGQSLVTASDDKTVKVW 130
            S  Q L T S D  +KVW
Sbjct: 104 ASLNQHLYTGSWDTKIKVW 48
>27525
          Length = 828

 Score = 28.9 bits (63), Expect = 4.2,   Method: Compositional matrix adjust.
 Identities = 15/51 (29%), Positives = 25/51 (49%)
 Frame = +2

Query: 215 DARTHRLLQHYQLHSAAVNALSFHPSGNYLITASSDSTLKILDLMEGRLLY 265
           D R  R    +Q+  A +NA+SF P G+ L     D  + +  + E  L++
Sbjct: 32  DGREPR--NSFQVGQAQINAISFSPDGSQLAVGCHDGFVHVYVVHEDGLVF 178
>38362
          Length = 1255

 Score = 28.1 bits (61), Expect = 7.5,   Method: Compositional matrix adjust.
 Identities = 52/241 (21%), Positives = 95/241 (39%), Gaps = 43/241 (17%)
 Frame = -1

Query: 105  TVRSVHFCSD--GQSLVTASDDKTVKVWSTHRQRFLF----SLTQHINWVRCAKFSPD-- 156
            TVR V +     GQ L T S D+T  VW     +  F    SL      V   KF+P   
Sbjct: 1243 TVRVVSWAHPEFGQVLATCSFDRTAAVWEKEAGQNHFLKRTSLVDSRTSVTDVKFAPKHL 1064

Query: 157  GRLIVSASDDKTVKLWDKTSRECIHSYCEHGGF-----VTYVDFHPSGT--CIAAAGMDN 209
            G  + ++S D  +++++      + ++     F      + + ++PS     + A G D+
Sbjct: 1063 GLQLATSSADGIIRIYEAVDVMNLSNWSLQHEFNCRISCSCMTWNPSRVHPPMIATGSDD 884

Query: 210  T-------VKVWD----ARTHRLLQHYQLHSAAVNALSFHPS--GNYLITASSDSTLKIL 256
            +       V +++     R    ++     +  V+ + F P+   +Y + A +   L I+
Sbjct: 883  SNPSSGAKVGIYEYSDVNRKWNKVESLGTVTDPVHDIYFAPNVGRSYHLLAIASKELSIV 704

Query: 257  DL---------------MEGRLLYTLHGHQGPATTVAFSRTGEYFASGGSDEQVMVWKSN 301
             L                E R +     H      V+++ TG    S G+D  V +WK+N
Sbjct: 703  SLKPLRKEPSSGSSSSKFEIRQVGLFDSHDSQVWRVSWNVTGTILVSSGADGCVRIWKAN 524

Query: 302  F 302
            +
Sbjct: 523  Y 521
>30679
          Length = 1025

 Score = 27.7 bits (60), Expect = 7.9,   Method: Compositional matrix adjust.
 Identities = 13/57 (22%), Positives = 27/57 (47%)
 Frame = +1

Query: 34 LASGSMDSTLMIWHMKSQSRAYRFTGHKDAVTCVNFSPSGHLLASGSRDKTVRIWVP 90
          L S   D   ++W+++          H D +  ++++  G + A+ S+DK +R   P
Sbjct: 7  LLSAGFDYKCVVWNVEQAEPVNIVDCHTDTIFSMSWNRXGSMFATTSKDKKLRTIDP 177
>37142
          Length = 327

 Score = 27.7 bits (60), Expect = 8.1,   Method: Composition-based stats.
 Identities = 24/77 (31%), Positives = 37/77 (48%), Gaps = 6/77 (7%)
 Frame = +2

Query: 18  HRDAVTCVDFS-LNTKHLASGSMDSTLMIWHMKSQSRAYRFTGHK----DAVTCVNFSPS 72
           H  AV  +DF+   T  LASG+ +S + IW +          G K    + V+CV ++  
Sbjct: 101 HTGAVKALDFNPFQTNLLASGASESEIYIWDLNKPDNPMT-PGQKSQPPEEVSCVAWNRQ 277

Query: 73  -GHLLASGSRDKTVRIW 88
             H+LAS    + V +W
Sbjct: 278 VQHILASNFAARCV-VW 325
>03177
          Length = 1242

 Score = 27.7 bits (60), Expect = 9.7,   Method: Compositional matrix adjust.
 Identities = 19/45 (42%), Positives = 26/45 (57%)
 Frame = +1

Query: 330 LPVPPGRDRSLESVQGEPQESISMPQTLTSTLEHIVGQLDILTQT 374
           LP P   +R   +++     +IS+  TLTSTLEHI   +  LTQT
Sbjct: 922 LP-PESSERKNNNIKRTYSHTISLLITLTSTLEHI-NTIKQLTQT 1050
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31711997|ref|NP_853626.1| protein phosphatase 1,
regulatory (inhibitor) subunit 9A [Mus musculus]
         (1095 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

27345                                                                 115   8e-26
05388                                                                  68   2e-11
06047                                                                  67   4e-11
29705                                                                  48   3e-05
07218                                                                  42   0.002
20073                                                                  39   0.015
30588                                                                  38   0.023
12404                                                                  34   0.38 
31117                                                                  33   0.83 
37239                                                                  31   2.4  
>27345
          Length = 496

 Score =  115 bits (289), Expect = 8e-26,   Method: Compositional matrix adjust.
 Identities = 56/76 (73%), Positives = 65/76 (85%)
 Frame = +3

Query: 532 KLGIFVKTVTDGGAAQRDGRIQVNDQIVEVDGISLVGVTQNFAATVLRNTKGNVRFVIGR 591
           KLGIF+KT+TDGGAAQ+DGRIQVNDQI+EVDG SLVGVTQ +AA+VLRNT G V F IGR
Sbjct: 18  KLGIFIKTLTDGGAAQKDGRIQVNDQIIEVDGKSLVGVTQAYAASVLRNTSGQVTFHIGR 197

Query: 592 EKPGQVSEVAQLISQT 607
           +K    SEVA+LI Q+
Sbjct: 198 DKDPAKSEVARLIQQS 245
>05388
          Length = 879

 Score = 67.8 bits (164), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 34/78 (43%), Positives = 46/78 (58%), Gaps = 3/78 (3%)
 Frame = +2

Query: 965  IDDEILDDGQSPK---HTQSQNRAVHEWSVQQVSHWLMSLSLDQYVPEFSAQSISGEQLL 1021
            I +   +DG SP      Q Q   V EWS + V  WL+S+ L++Y   F  +SI+G QL 
Sbjct: 599  ISNAPAEDGASPSKRGQDQGQPSGVMEWSWESVCDWLISIDLEKYTDSFMEKSITGTQLF 778

Query: 1022 QLDGNKLKALGMTSSQDR 1039
             LD  KLK+LG+ SS+DR
Sbjct: 779  MLDSTKLKSLGIASSKDR 832
>06047
          Length = 445

 Score = 67.0 bits (162), Expect = 4e-11,   Method: Compositional matrix adjust.
 Identities = 33/72 (45%), Positives = 44/72 (61%), Gaps = 3/72 (4%)
 Frame = -2

Query: 971  DDGQSPK---HTQSQNRAVHEWSVQQVSHWLMSLSLDQYVPEFSAQSISGEQLLQLDGNK 1027
            +DG SP      Q Q   V EWS + V  WL+S+ L++Y   F  +SI+G QL  LD  K
Sbjct: 315  EDGASPSKRGQDQGQPSGVMEWSWESVCDWLISIDLEKYTDSFMEKSITGTQLFMLDSTK 136

Query: 1028 LKALGMTSSQDR 1039
            LK+LG+ SS+DR
Sbjct: 135  LKSLGIASSKDR 100
>29705
          Length = 674

 Score = 47.8 bits (112), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 25/68 (36%), Positives = 42/68 (61%)
 Frame = -1

Query: 534 GIFVKTVTDGGAAQRDGRIQVNDQIVEVDGISLVGVTQNFAATVLRNTKGNVRFVIGREK 593
           GIF+  V +GG+A++DGRI V D+++ V+  +L  VT   A   L++T   VR  I   K
Sbjct: 362 GIFITKVIEGGSAEQDGRIAVMDRLLAVNEHNLEDVTHEEAVAALKSTGDVVRLTIA--K 189

Query: 594 PGQVSEVA 601
           P  +++++
Sbjct: 188 PTYIADLS 165

 Score = 29.6 bits (65), Expect = 6.4,   Method: Compositional matrix adjust.
 Identities = 12/19 (63%), Positives = 16/19 (84%)
 Frame = -2

Query: 543 GGAAQRDGRIQVNDQIVEV 561
           GGAA  DGR+++ND IV+V
Sbjct: 622 GGAAAEDGRLRLNDIIVKV 566
>07218
          Length = 1715

 Score = 41.6 bits (96), Expect = 0.002,   Method: Composition-based stats.
 Identities = 20/49 (40%), Positives = 28/49 (57%)
 Frame = +1

Query: 986  VHEWSVQQVSHWLMSLSLDQYVPEFSAQSISGEQLLQLDGNKLKALGMT 1034
            +  W+  +V  WL SLSL +Y   F +  I G +LL L+   LK LG+T
Sbjct: 190  IRSWTTDEVGAWLESLSLGEYRANFISHEIRGAELLSLERRDLKDLGVT 336
>20073
          Length = 582

 Score = 38.5 bits (88), Expect = 0.015,   Method: Composition-based stats.
 Identities = 24/81 (29%), Positives = 43/81 (53%), Gaps = 1/81 (1%)
 Frame = +3

Query: 521 GMGVGADAGLEKLG-IFVKTVTDGGAAQRDGRIQVNDQIVEVDGISLVGVTQNFAATVLR 579
           G+G     G E+   I++  +  GG A R   ++  DQ++ V+G+S+ G     A  +L+
Sbjct: 3   GLGFNVMGGKEQSSPIYISRIIPGGVADRLNCLKRGDQLLSVNGVSVEGEYHEKAVELLK 182

Query: 580 NTKGNVRFVIGREKPGQVSEV 600
             +G+VR V+ R  P  + E+
Sbjct: 183 LAQGSVRLVV-RYTPQILEEM 242
>30588
          Length = 579

 Score = 37.7 bits (86), Expect = 0.023,   Method: Composition-based stats.
 Identities = 14/35 (40%), Positives = 24/35 (68%)
 Frame = +1

Query: 725 ENKERMLKLESYWIEAQTLCHTVNEHLKETQSQYQ 759
           E+  + +K+ + W+EA+ LC T+N HL E +S Y+
Sbjct: 376 ESCYKFVKMATSWMEAKVLCETMNSHLVEVESPYE 480
>12404
          Length = 1116

 Score = 33.9 bits (76), Expect = 0.38,   Method: Composition-based stats.
 Identities = 20/70 (28%), Positives = 37/70 (52%), Gaps = 2/70 (2%)
 Frame = -1

Query: 973  GQSPKHTQSQNRAVHEWSVQQVSHWLMSLSLDQYVPEFSA-QSISGEQLLQLDGNKL-KA 1030
            G+S  +  +    V +W+V  V+ WL +L   +   +F+  Q++ G  LL ++ + L  A
Sbjct: 1023 GKSDNNKGTSEIPVEKWAVSDVAQWLNTLGWARNYSQFAVNQTVDGLALLSMETSDLMNA 844

Query: 1031 LGMTSSQDRA 1040
            L +T S  R+
Sbjct: 843  LQVTDSYHRS 814
>31117
          Length = 856

 Score = 32.7 bits (73), Expect = 0.83,   Method: Composition-based stats.
 Identities = 13/46 (28%), Positives = 24/46 (52%)
 Frame = +3

Query: 989  WSVQQVSHWLMSLSLDQYVPEFSAQSISGEQLLQLDGNKLKALGMT 1034
            W+V QV+ W+  L    Y   F+   I G +L+ ++ +    +G+T
Sbjct: 90   WTVNQVAEWIEELGFPHYKSCFTTNMIDGRRLICIEASAFPNIGIT 227
>37239
          Length = 453

 Score = 31.2 bits (69), Expect = 2.4,   Method: Composition-based stats.
 Identities = 11/25 (44%), Positives = 20/25 (80%)
 Frame = -3

Query: 534 GIFVKTVTDGGAAQRDGRIQVNDQI 558
           GI+++ +T GGAA +DG++ V D++
Sbjct: 76  GIYIRHITIGGAAAKDGQLAVGDEL 2
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|45504359|ref|NP_031536.2| vacuolar H+ ATPase E1 [Mus
musculus]
         (226 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

05758                                                                 112   8e-26
23561                                                                  65   2e-11
>05758
          Length = 1666

 Score =  112 bits (281), Expect = 8e-26,   Method: Compositional matrix adjust.
 Identities = 56/100 (56%), Positives = 70/100 (70%), Gaps = 2/100 (2%)
 Frame = +3

Query: 129 EPRMIVRCRKQDFPLVKAAVQKAIPMYKIATK--KDVDVQIDQEAYLPEEIAGGVEIYNG 186
           EP +I+RCR QD  LVK  +  AI  YK ATK  K+V V +D E +L  E++GGVE+ N 
Sbjct: 33  EPVVILRCRAQDLELVKEVLGSAISSYKEATKGTKEVKVNLDTEHFLSSEVSGGVELLNR 212

Query: 187 DRKIKVSNTLESRLDLIAQQMMPEVRGALFGANANRKFLD 226
             KIKV NTL+SRLDL+ QQM+PE+R  LFG N NR+F D
Sbjct: 213 SEKIKVVNTLDSRLDLMYQQMLPELRDILFGHNPNRRFTD 332
>23561
          Length = 1175

 Score = 65.1 bits (157), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 30/47 (63%), Positives = 36/47 (76%)
 Frame = +1

Query: 180 GVEIYNGDRKIKVSNTLESRLDLIAQQMMPEVRGALFGANANRKFLD 226
           GVE+ N   KIKV NTL+SRLDL+ QQM+PE+R  LFG N NR+F D
Sbjct: 1   GVELLNRSEKIKVVNTLDSRLDLMYQQMLPELRDILFGHNPNRRFTD 141
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|51921285|ref|NP_001004144.1| G protein-coupled
receptor kinase-interactor 1 [Mus musculus]
         (770 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

02351                                                                 115   9e-26
06253                                                                  45   9e-05
05924                                                                  45   1e-04
00540                                                                  44   3e-04
08473                                                                  42   7e-04
13462                                                                  42   0.001
21532                                                                  42   0.001
14005                                                                  40   0.003
13900                                                                  40   0.003
09292                                                                  39   0.007
09180                                                                  39   0.009
19166                                                                  39   0.010
20036                                                                  38   0.013
30463                                                                  37   0.030
12417                                                                  37   0.031
11295                                                                  35   0.095
22305                                                                  35   0.15 
25470                                                                  35   0.16 
02114                                                                  34   0.23 
20884                                                                  34   0.24 
36879                                                                  33   0.36 
20792                                                                  33   0.42 
16585                                                                  33   0.50 
02055                                                                  33   0.51 
15772                                                                  32   0.72 
12886                                                                  32   1.2  
05396                                                                  31   1.7  
17893                                                                  30   5.2  
15359                                                                  29   6.1  
25464                                                                  29   7.2  
28113                                                                  28   9.4  
>02351
          Length = 939

 Score =  115 bits (287), Expect = 9e-26,   Method: Compositional matrix adjust.
 Identities = 68/213 (31%), Positives = 108/213 (50%), Gaps = 3/213 (1%)
 Frame = +3

Query: 10  VCADCSAPDPGWASISRGVLVCDECCSVHRSLGRHISIVKHLRHSAWPPTLLQMVHTLAS 69
           +C DC  P P WASI+ G ++C ECC VHR++G HIS V+ L    WPP + +++ ++ +
Sbjct: 30  ICVDCGTPSPSWASINLGAVMCIECCGVHRNIGTHISRVRSLDLDDWPPEVTKVMTSIGN 209

Query: 70  NGANSIWEHSLLDPAQVQSGRRKANPQDKVHPIKSEFIRAKYQMLAFVHKLPCRDDDGVT 129
             ANS+WE +         GR K          K ++I+AKY+   F+  LP  D     
Sbjct: 210 YVANSVWEAN-------TKGRSKPTSSSNREE-KEQWIKAKYEAKEFLPPLPYID----- 350

Query: 130 AKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFHP---EKGTTPLHVAAKAGQTLQAELL 186
              +++QL  ++   ++   + +L   A  +   P   + G T LH+AA  G  +  +LL
Sbjct: 351 -IPINQQLIDALVREDIRNIIIILGHAASDDINSPYGKDDGRTALHIAAALGNVVYVQLL 527

Query: 187 VVYGADPGSPDVNGRTPIDYARQAGHHELAERL 219
           + Y A+    D  GR  + YAR +G  E  + L
Sbjct: 528 LWYCANVKVVDHEGRNALWYARTSGSVECTDLL 626
>06253
          Length = 1049

 Score = 45.4 bits (106), Expect = 9e-05,   Method: Compositional matrix adjust.
 Identities = 38/115 (33%), Positives = 55/115 (47%), Gaps = 17/115 (14%)
 Frame = -1

Query: 123 RDDDGVTAKDLSK--------------QLHSSVRTGNLETCLRLLS-LGAQANFFHPEKG 167
           R+ DG TA DL+               +L  + R+GN E  + LL+ L       H   G
Sbjct: 761 RNTDGKTALDLADASAKAVLTGEYKKDELLEAARSGNEEQMMALLTPLNVNC---HASDG 591

Query: 168 --TTPLHVAAKAGQTLQAELLVVYGADPGSPDVNGRTPIDYARQAGHHELAERLV 220
             +TPLH+AA   +T   +LL+ +GAD  + D  G  P+  A   GH E+ E L+
Sbjct: 590 RKSTPLHLAAGYNRTRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHFEVTEMLL 426

 Score = 37.7 bits (86), Expect = 0.020,   Method: Compositional matrix adjust.
 Identities = 30/89 (33%), Positives = 43/89 (48%)
 Frame = -1

Query: 137 LHSSVRTGNLETCLRLLSLGAQANFFHPEKGTTPLHVAAKAGQTLQAELLVVYGADPGSP 196
           LH++   G+ E    LL  GA  N     +  TPLH AA   +     LL+ +GADP   
Sbjct: 476 LHNACSYGHFEVTEMLLXAGASVNAVDLWQ-FTPLHEAASKSRVEVCSLLLAHGADPNLV 300

Query: 197 DVNGRTPIDYARQAGHHELAERLVECQYE 225
           + + ++ ID A      EL ER+   Q+E
Sbjct: 299 NCHSKSIIDVAPT---RELQERI---QFE 231

 Score = 34.3 bits (77), Expect = 0.19,   Method: Compositional matrix adjust.
 Identities = 28/85 (32%), Positives = 39/85 (45%)
 Frame = -1

Query: 123 RDDDGVTAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFHPEKGTTPLHVAAKAGQTLQ 182
           RDD G+        LH++   G+ E    LL  GA  N        TPLH AA  G+   
Sbjct: 959 RDDGGLI------PLHNACSFGHAEVVQLLLRHGADPNA-RDNWNYTPLHEAAIKGKIDV 801

Query: 183 AELLVVYGADPGSPDVNGRTPIDYA 207
             +L+   ADP   + +G+T +D A
Sbjct: 800 CIVLLQQCADPNIRNTDGKTALDLA 726

 Score = 33.1 bits (74), Expect = 0.43,   Method: Compositional matrix adjust.
 Identities = 25/78 (32%), Positives = 34/78 (43%)
 Frame = -1

Query: 134  SKQLHSSVRTGNLETCLRLLSLGAQANFFHPEKGTTPLHVAAKAGQTLQAELLVVYGADP 193
            S  LH +   G  +    LL  GA  +    + G  PLH A   G     +LL+ +GADP
Sbjct: 1043 STPLHFAAGFGRKDVVEHLLENGANVHA-RDDGGLIPLHNACSFGHAEVVQLLLRHGADP 867

Query: 194  GSPDVNGRTPIDYARQAG 211
             + D    TP+  A   G
Sbjct: 866  NARDNWNYTPLHEAAIKG 813
>05924
          Length = 704

 Score = 44.7 bits (104), Expect = 1e-04,   Method: Composition-based stats.
 Identities = 28/87 (32%), Positives = 44/87 (50%)
 Frame = +1

Query: 134 SKQLHSSVRTGNLETCLRLLSLGAQANFFHPEKGTTPLHVAAKAGQTLQAELLVVYGADP 193
           S  LH +V   + +    L+  GA AN  + + G T LH+A + G T   ++L+  G D 
Sbjct: 67  STLLHEAVSMASEDLVQMLIKAGANANSTN-QDGRTALHLACRGGYTNIVQILIAAGTDV 243

Query: 194 GSPDVNGRTPIDYARQAGHHELAERLV 220
               V+G+T +  A   GH E+  +LV
Sbjct: 244 NRRTVDGKTCLHVAVWRGHTEVVVKLV 324

 Score = 35.4 bits (80), Expect = 0.096,   Method: Composition-based stats.
 Identities = 30/102 (29%), Positives = 44/102 (43%)
 Frame = +1

Query: 129 TAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFHPEKGTTPLHVAAKAGQTLQAELLVV 188
           T +D    LH + R G       L++ G   N      G T LHVA   G T     LV 
Sbjct: 151 TNQDGRTALHLACRGGYTNIVQILIAAGTDVNR-RTVDGKTCLHVAVWRGHTEVVVKLVN 327

Query: 189 YGADPGSPDVNGRTPIDYARQAGHHELAERLVECQYELTDRL 230
            GAD   PD  G +P+ +A ++ +  +   LV    ++  R+
Sbjct: 328 AGADVNIPDSVGCSPLYWAARSNYTAILTVLVNAGAKVNYRV 453
>00540
          Length = 3034

 Score = 43.5 bits (101), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 29/77 (37%), Positives = 42/77 (54%)
 Frame = -2

Query: 144  GNLETCLRLLSLGAQANFFHPEKGTTPLHVAAKAGQTLQAELLVVYGADPGSPDVNGRTP 203
            G+L+    LL LGAQ N     KG T LH +A++G+    +LL+  GA   + D  G+TP
Sbjct: 2838 GHLDVVEYLLYLGAQVNR-RSVKGNTALHDSAESGKLSIMKLLLSKGAKM-AKDAYGQTP 2665

Query: 204  IDYARQAGHHELAERLV 220
            +  A   GH E+   L+
Sbjct: 2664 LSAAAMTGHEEIVRYLI 2614
>08473
          Length = 942

 Score = 42.4 bits (98), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 29/81 (35%), Positives = 38/81 (46%)
 Frame = -1

Query: 137 LHSSVRTGNLETCLRLLSLGAQANFFHPEKGTTPLHVAAKAGQTLQAELLVVYGADPGSP 196
           L  +   G +  C  L+  GA  N    +   TPL VAA+ G     E L+  GA+P + 
Sbjct: 807 LFYAAHRGEISICKLLVDKGANVNAA-DKMLITPLMVAAREGNREAVEFLLKRGANPNTA 631

Query: 197 DVNGRTPIDYARQAGHHELAE 217
           D  G   + YA  AGH EL E
Sbjct: 630 DREGHLALYYAMAAGHPELRE 568

 Score = 29.6 bits (65), Expect = 5.0,   Method: Compositional matrix adjust.
 Identities = 24/85 (28%), Positives = 39/85 (45%)
 Frame = -1

Query: 137 LHSSVRTGNLETCLRLLSLGAQANFFHPEKGTTPLHVAAKAGQTLQAELLVVYGADPGSP 196
           +H+ ++ G   TC+ +              G TPL  AA  G+    +LLV  GA+  + 
Sbjct: 870 VHALLQGGANPTCMEM-------------GGKTPLFYAAHRGEISICKLLVDKGANVNAA 730

Query: 197 DVNGRTPIDYARQAGHHELAERLVE 221
           D    TP+  A + G+ E  E L++
Sbjct: 729 DKMLITPLMVAAREGNREAVEFLLK 655
>13462
          Length = 1388

 Score = 41.6 bits (96), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 31/101 (30%), Positives = 42/101 (41%)
 Frame = +3

Query: 144 GNLETCLRLLSLGAQANFFHPEKGTTPLHVAAKAGQTLQAELLVVYGADPGSPDVNGRTP 203
           GNL     LL+ GAQ N    E G T LH+A          LL+ +G D    D++  TP
Sbjct: 216 GNLGIVSMLLAYGAQPNV-QDEDGNTALHLACSESNVDVVRLLLEWGGDVAVADIDNETP 392

Query: 204 IDYARQAGHHELAERLVECQYELTDRLAFYLCGRKPDHKNG 244
           +  A  A   EL + L+               G  P+H +G
Sbjct: 393 LVRACLANSVELVDLLLH-------------AGSDPNHSHG 476

 Score = 31.2 bits (69), Expect = 1.7,   Method: Compositional matrix adjust.
 Identities = 24/92 (26%), Positives = 37/92 (40%)
 Frame = +3

Query: 113 MLAFVHKLPCRDDDGVTAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFHPEKGTTPLH 172
           M+  +H     D +G     L+   H+ +        +RLL L           G TPLH
Sbjct: 600 MMKVLHNYGV-DVNGTGRLGLTALHHACISQEATHDAVRLLLLWGSNPNLVTGTGDTPLH 776

Query: 173 VAAKAGQTLQAELLVVYGADPGSPDVNGRTPI 204
            A +     +  LL++YGAD    D    +P+
Sbjct: 777 FACQTFAVSKVRLLLMYGADVNQIDGTHTSPL 872
>21532
          Length = 460

 Score = 41.6 bits (96), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 31/103 (30%), Positives = 46/103 (44%), Gaps = 6/103 (5%)
 Frame = -1

Query: 123 RDDDGVTAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFHP------EKGTTPLHVAAK 176
           RD+ G T         ++   GNL     LL+ G   ++  P          TPLH+A++
Sbjct: 409 RDNTGCTP------FANACCLGNLAAVKALLTPGESPSWSKPMINVRDNSQNTPLHLASQ 248

Query: 177 AGQTLQAELLVVYGADPGSPDVNGRTPIDYARQAGHHELAERL 219
            G T   ELLV + AD  + + +G  P+  ARQ  H  +   L
Sbjct: 247 EGHTAIVELLVEHKADLAAKNDSGHNPLSLARQYKHENVVAVL 119

 Score = 33.1 bits (74), Expect = 0.45,   Method: Compositional matrix adjust.
 Identities = 28/85 (32%), Positives = 36/85 (42%), Gaps = 7/85 (8%)
 Frame = -1

Query: 152 LLSLGAQANFFHPEKGTTPLHVAAKAGQTLQAELLVVYGADPG--SPDVNGR-----TPI 204
           LLS GA  N      G TP   A   G     + L+  G  P    P +N R     TP+
Sbjct: 439 LLSHGADVNI-RDNTGCTPFANACCLGNLAAVKALLTPGESPSWSKPMINVRDNSQNTPL 263

Query: 205 DYARQAGHHELAERLVECQYELTDR 229
             A Q GH  + E LVE + +L  +
Sbjct: 262 HLASQEGHTAIVELLVEHKADLAAK 188
>14005
          Length = 1745

 Score = 40.4 bits (93), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 26/88 (29%), Positives = 43/88 (48%)
 Frame = -1

Query: 133  LSKQLHSSVRTGNLETCLRLLSLGAQANFFHPEKGTTPLHVAAKAGQTLQAELLVVYGAD 192
            L   L+ +    ++E   +L+  GA+ N +  E   TP H   K G    A  L+ +GA+
Sbjct: 1643 LRPALYFACMGNDIELVKQLVRYGARVNAYSTETWWTPFHACCKRGDPRIALYLLRHGAN 1464

Query: 193  PGSPDVNGRTPIDYARQAGHHELAERLV 220
              S  V+G+TP+  A +    E+A  L+
Sbjct: 1463 KESRTVDGKTPLVVACKNDKAEVALLLI 1380

 Score = 37.0 bits (84), Expect = 0.028,   Method: Compositional matrix adjust.
 Identities = 30/85 (35%), Positives = 41/85 (48%), Gaps = 1/85 (1%)
 Frame = -1

Query: 137  LHSSVRTGNLETCLRLLSLGAQANFFHPEKGTTPLHVAAKAGQTLQAELLVVYGADPG-S 195
             H+  + G+    L LL  GA         G TPL VA K  +   A LL+  GA+   S
Sbjct: 1529 FHACCKRGDPRIALYLLRHGANKES-RTVDGKTPLVVACKNDKAEVALLLIRSGANVNVS 1353

Query: 196  PDVNGRTPIDYARQAGHHELAERLV 220
             D+   TP+ +A Q  + EL +RLV
Sbjct: 1352 CDITANTPVHFACQRPNIELLKRLV 1278

 Score = 32.3 bits (72), Expect = 0.75,   Method: Compositional matrix adjust.
 Identities = 20/65 (30%), Positives = 28/65 (43%)
 Frame = -1

Query: 147  ETCLRLLSLGAQANFFHPEKGTTPLHVAAKAGQTLQAELLVVYGADPGSPDVNGRTPIDY 206
            E  L L+  GA  N        TP+H A +       + LV++GAD   P+  G T +  
Sbjct: 1400 EVALLLIRSGANVNVSCDITANTPVHFACQRPNIELLKRLVLHGADVDKPNAKGHTALHV 1221

Query: 207  ARQAG 211
            A   G
Sbjct: 1220 ASVRG 1206
>13900
          Length = 751

 Score = 40.0 bits (92), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 31/106 (29%), Positives = 50/106 (47%), Gaps = 1/106 (0%)
 Frame = +1

Query: 131 KDLSKQLHSSVRTGNLETCLRLLSL-GAQANFFHPEKGTTPLHVAAKAGQTLQAELLVVY 189
           +DL + + S    G++ T   L+ L   + N   P  G +PLH+A +     +A+ L+  
Sbjct: 178 RDLLRNIDSX---GSMVTFRFLIRLPWVRLNCQDPRSGQSPLHLAVRVNDFHKAKKLLKL 348

Query: 190 GADPGSPDVNGRTPIDYARQAGHHELAERLVECQYELTDRLAFYLC 235
           G+DP  PD +G TP+   R A  HE             + + FY+C
Sbjct: 349 GSDPLLPDFSGITPL---RMAQGHE------------YNAIVFYMC 441
>09292
          Length = 1486

 Score = 39.3 bits (90), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 29/119 (24%), Positives = 56/119 (47%), Gaps = 2/119 (1%)
 Frame = -2

Query: 94   NPQDKVH--PIKSEFIRAKYQMLAFVHKLPCRDDDGVTAKDLSKQLHSSVRTGNLETCLR 151
            N +DK H  P+ +  ++    ++ ++       + G  A   ++ +  +V+ G  E    
Sbjct: 1182 NAEDKDHLTPVFNACVKNDTDIVRYL------LESGARANTTARPIFHAVKYGYSEIVQL 1021

Query: 152  LLSLGAQANFFHPEKGTTPLHVAAKAGQTLQAELLVVYGADPGSPDVNGRTPIDYARQA 210
            LL  GA  N     K  +PLH+A + G    A  +++ GA+  + D +G TP+  + +A
Sbjct: 1020 LLVHGAAVNSLPGTK--SPLHIACRNGNIEMARTVIIAGANVNAVDKDGNTPLHISVRA 850

 Score = 34.7 bits (78), Expect = 0.15,   Method: Compositional matrix adjust.
 Identities = 35/115 (30%), Positives = 53/115 (46%), Gaps = 5/115 (4%)
 Frame = -2

Query: 127 GVTAKDLSKQL----HSSVRTGNLETCLRLLSLGAQANFFHPE-KGTTPLHVAAKAGQTL 181
           G  + +LS +L    H +V  GN++  +RL+ L   ++   P+ +   PLH+A       
Sbjct: 711 GSCSNELSSKLWTPLHYAVIGGNVDI-VRLV-LQGSSDVNSPDGRNNAPLHLACMKQCIG 538

Query: 182 QAELLVVYGADPGSPDVNGRTPIDYARQAGHHELAERLVECQYELTDRLAFYLCG 236
            A  L+ +GA+      NGRTP+  A    HH L         EL   L  Y+CG
Sbjct: 537 IARCLLRHGANVNVSGYNGRTPLHIA--ISHHNL---------ELV--LLLYMCG 412

 Score = 32.3 bits (72), Expect = 0.75,   Method: Compositional matrix adjust.
 Identities = 26/86 (30%), Positives = 38/86 (44%), Gaps = 2/86 (2%)
 Frame = -2

Query: 137  LHSSVRTGNLETCLRLLSLGAQANF--FHPEKGTTPLHVAAKAGQTLQAELLVVYGADPG 194
            LH + +  ++ET L  L +G   +    H E   T LH     G    A +L+ + AD  
Sbjct: 1449 LHCAXQLQDVETLLAYLDIGMHVDTRDSHHE---TALHAVCYVGSVKMASVLLKHXADVN 1279

Query: 195  SPDVNGRTPIDYARQAGHHELAERLV 220
            + +   RTP+      GH  L E LV
Sbjct: 1278 ARNNVDRTPLHIXAIEGHLGLVEELV 1201

 Score = 28.9 bits (63), Expect = 8.5,   Method: Compositional matrix adjust.
 Identities = 25/85 (29%), Positives = 38/85 (44%)
 Frame = -2

Query: 137  LHSSVRTGNLETCLRLLSLGAQANFFHPEKGTTPLHVAAKAGQTLQAELLVVYGADPGSP 196
            LH+    G+++    LL   A  N  +     TPLH+ A  G     E LV +GAD  + 
Sbjct: 1350 LHAVCYVGSVKMASVLLKHXADVNARN-NVDRTPLHIXAIEGHLGLVEELVRHGADFNAE 1174

Query: 197  DVNGRTPIDYARQAGHHELAERLVE 221
            D +  TP+  A      ++   L+E
Sbjct: 1173 DKDHLTPVFNACVKNDTDIVRYLLE 1099
>09180
          Length = 610

 Score = 38.5 bits (88), Expect = 0.009,   Method: Compositional matrix adjust.
 Identities = 25/100 (25%), Positives = 42/100 (42%)
 Frame = +3

Query: 163 HPEKGTTPLHVAAKAGQTLQAELLVVYGADPGSPDVNGRTPIDYARQAGHHELAERLVEC 222
           HP+ G T LHV+A  G      +L+  G D  + D +G T +  A   G  +  + LV+ 
Sbjct: 153 HPKTGATALHVSAAKGYINVMNVLLQAGVDINAQDADGWTSLHAAVHWGQEDSCQVLVD- 329

Query: 223 QYELTDRLAFYLCGRKPDHKNGHYIIPQMADRSRQKCMSQ 262
                     + C     +  GH +   +AD+   K + +
Sbjct: 330 ----------HFCDMDVKNNAGHTVFD-LADKEMLKVLEE 416
>19166
          Length = 447

 Score = 38.5 bits (88), Expect = 0.010,   Method: Compositional matrix adjust.
 Identities = 19/56 (33%), Positives = 29/56 (51%)
 Frame = +1

Query: 166 KGTTPLHVAAKAGQTLQAELLVVYGADPGSPDVNGRTPIDYARQAGHHELAERLVE 221
            G TPLH+A K  +    ELL+ YGA   +   +G TP+  +   GH  +   L++
Sbjct: 55  NGFTPLHIACKKNRIKVVELLLKYGASIDATTESGLTPLHVSSFMGHMNIVIYLIQ 222

 Score = 35.4 bits (80), Expect = 0.081,   Method: Compositional matrix adjust.
 Identities = 24/84 (28%), Positives = 39/84 (46%)
 Frame = +1

Query: 137 LHSSVRTGNLETCLRLLSLGAQANFFHPEKGTTPLHVAAKAGQTLQAELLVVYGADPGSP 196
           LH + +   ++    LL  GA  +    E G TPLHV++  G       L+ + A P +P
Sbjct: 70  LHIACKKNRIKVVELLLKYGASIDAT-TESGLTPLHVSSFMGHMNIVIYLIQHNAYPDTP 246

Query: 197 DVNGRTPIDYARQAGHHELAERLV 220
            V G T +  A +A   ++   L+
Sbjct: 247 TVRGETSLHLAARANQTDIIRILL 318
>20036
          Length = 1849

 Score = 38.1 bits (87), Expect = 0.013,   Method: Compositional matrix adjust.
 Identities = 26/83 (31%), Positives = 37/83 (44%), Gaps = 3/83 (3%)
 Frame = +3

Query: 150  LRLLSLGAQANFFHPEKGTTPLHVAAKAGQTLQAELLVVYGADPGSPDVNGRTPIDYARQ 209
            +R L L    N    + G T L +A    +T   ELL+  GAD    D +G T +  A +
Sbjct: 1050 IRQLFLAGDINACAEQTGQTALMLATSQCRTDMVELLLETGADCNQQDFDGSTALMCACE 1229

Query: 210  AGHHELAERLV---ECQYELTDR 229
             GH  + + L+    C   LTD 
Sbjct: 1230 HGHTAIVQLLLAQPHCDATLTDN 1298
>30463
          Length = 412

 Score = 37.0 bits (84), Expect = 0.030,   Method: Composition-based stats.
 Identities = 27/91 (29%), Positives = 43/91 (47%)
 Frame = -1

Query: 138 HSSVRTGNLETCLRLLSLGAQANFFHPEKGTTPLHVAAKAGQTLQAELLVVYGADPGSPD 197
           H +   G+    + L  +GA  +    +K  TPLH+A+ AG     + LV   A   + D
Sbjct: 373 HLAAMNGHSNAVMVLNIMGASIDCRTVDK-QTPLHLASSAGHIECVKCLVANKASLTAED 197

Query: 198 VNGRTPIDYARQAGHHELAERLVECQYELTD 228
              RT  D A Q G +++A+ L  C  +L +
Sbjct: 196 AFSRTAYDLADQYGQNDVADFLHHCLLDLDN 104

 Score = 35.0 bits (79), Expect = 0.100,   Method: Composition-based stats.
 Identities = 23/66 (34%), Positives = 32/66 (48%)
 Frame = -1

Query: 167 GTTPLHVAAKAGQTLQAELLVVYGADPGSPDVNGRTPIDYARQAGHHELAERLVECQYEL 226
           G T  H+AA  G +    +L + GA      V+ +TP+  A  AGH E  + LV  +  L
Sbjct: 388 GYTATHLAAMNGHSNAVMVLNIMGASIDCRTVDKQTPLHLASSAGHIECVKCLVANKASL 209

Query: 227 TDRLAF 232
           T   AF
Sbjct: 208 TAEDAF 191
>12417
          Length = 954

 Score = 37.0 bits (84), Expect = 0.031,   Method: Compositional matrix adjust.
 Identities = 24/63 (38%), Positives = 31/63 (49%)
 Frame = +2

Query: 149 CLRLLSLGAQANFFHPEKGTTPLHVAAKAGQTLQAELLVVYGADPGSPDVNGRTPIDYAR 208
           C +L+  GA  N    E G TPLH A+  G     +LL+  GAD  + D  G T +  A 
Sbjct: 281 CSQLIQTGADVNSA-TEHGRTPLHXASAQGHGHIVDLLLEKGADIDAEDDYGDTALSIAD 457

Query: 209 QAG 211
           Q G
Sbjct: 458 QFG 466

 Score = 35.8 bits (81), Expect = 0.060,   Method: Compositional matrix adjust.
 Identities = 24/86 (27%), Positives = 35/86 (40%), Gaps = 13/86 (15%)
 Frame = +2

Query: 165 EKGTTPLHVAAKAGQTLQAELLVVYGADPGSPDVNGRTPIDYARQAGHHELAERLVE--- 221
           E+ +  L +AA  G       L+  GAD  S   +GRTP+  A   GH  + + L+E   
Sbjct: 227 ERASVALAMAANRGLDKMCSQLIQTGADVNSATEHGRTPLHXASAQGHGHIVDLLLEKGA 406

Query: 222 ----------CQYELTDRLAFYLCGR 237
                         + D+  F  CGR
Sbjct: 407 DIDAEDDYGDTALSIADQFGFKSCGR 484
>11295
          Length = 1179

 Score = 35.4 bits (80), Expect = 0.095,   Method: Compositional matrix adjust.
 Identities = 30/103 (29%), Positives = 45/103 (43%), Gaps = 6/103 (5%)
 Frame = +1

Query: 152 LLSLGAQANF---FHPEKGTTPLHVAAKAGQTLQAELLVVYGADPGSPDVNGRTPIDYAR 208
           L+  GA  N    +H     TPLH  ++ G     +LL+   A+P   D  G TP+  A 
Sbjct: 631 LIKFGASVNCADHYH----YTPLHYISRRGHLTMLQLLLQGKAEPNVVDDEGITPLYIAS 798

Query: 209 QAGHHELAERLVECQYELTDRLAFYLCGRKPDH---KNGHYII 248
             GH  +   L++   ++     +  C R P H   K GH +I
Sbjct: 799 CEGHVTIVNILLQSGAKI-----YMPCARDPVHAACKAGHEVI 912

 Score = 33.1 bits (74), Expect = 0.44,   Method: Compositional matrix adjust.
 Identities = 32/106 (30%), Positives = 44/106 (41%), Gaps = 9/106 (8%)
 Frame = +1

Query: 124 DDDGV----TAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFHPEKGTTPLHVAAKAGQ 179
           + DG+    T+ D    LH +    + E    LL  GA A       G TPLHVA   G 
Sbjct: 136 NGDGIAVNATSNDHVTALHIACCLDDREMASLLLKYGAYAMAL-DVIGHTPLHVACWCGS 312

Query: 180 TLQAELLVVYGADPGSPDVN-----GRTPIDYARQAGHHELAERLV 220
                LL+    D    DVN     G+ P+  A + G H +  +L+
Sbjct: 313 EGVTRLLL----DRSDVDVNALDHDGKXPLRLASECGFHYIIRQLL 438
>22305
          Length = 426

 Score = 34.7 bits (78), Expect = 0.15,   Method: Composition-based stats.
 Identities = 24/73 (32%), Positives = 31/73 (42%)
 Frame = -3

Query: 140 SVRTGNLETCLRLLSLGAQANFFHPEKGTTPLHVAAKAGQTLQAELLVVYGADPGSPDVN 199
           SVR    +    LL  G  AN  +   G  PLH A          +L+ YGADP  P   
Sbjct: 364 SVRVNAADITTALLERGCSANERN-HWGILPLHEALCWENVEVGRVLLQYGADPNVPCET 188

Query: 200 GRTPIDYARQAGH 212
              P+ +A + GH
Sbjct: 187 NVVPLTFAARTGH 149
>25470
          Length = 400

 Score = 34.7 bits (78), Expect = 0.16,   Method: Composition-based stats.
 Identities = 28/85 (32%), Positives = 39/85 (45%)
 Frame = -3

Query: 123 RDDDGVTAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFHPEKGTTPLHVAAKAGQTLQ 182
           RDD G+        LH++   G+ E    LL  GA  N        TPLH AA  G+   
Sbjct: 311 RDDGGLIP------LHNACSFGHAEVVQLLLRHGADPNA-RDNWNYTPLHEAAIKGKIDV 153

Query: 183 AELLVVYGADPGSPDVNGRTPIDYA 207
             +L+   ADP   + +G+T +D A
Sbjct: 152 CIVLLQQCADPNIRNTDGKTALDLA 78

 Score = 30.8 bits (68), Expect = 2.3,   Method: Composition-based stats.
 Identities = 17/45 (37%), Positives = 22/45 (48%)
 Frame = -3

Query: 167 GTTPLHVAAKAGQTLQAELLVVYGADPGSPDVNGRTPIDYARQAG 211
           G  PLH A   G     +LL+ +GADP + D    TP+  A   G
Sbjct: 299 GLIPLHNACSFGHAEVVQLLLRHGADPNARDNWNYTPLHEAAIKG 165
>02114
          Length = 1072

 Score = 33.9 bits (76), Expect = 0.23,   Method: Compositional matrix adjust.
 Identities = 19/62 (30%), Positives = 28/62 (45%)
 Frame = +1

Query: 166 KGTTPLHVAAKAGQTLQAELLVVYGADPGSPDVNGRTPIDYARQAGHHELAERLVECQYE 225
           +G TP H+AA  GQ    + L   G    + D  G TP+  A   GH    + L+ C  +
Sbjct: 199 RGWTPAHIAAIRGQEGCIQALSNNGVSMSAKDTRGSTPLHLACAHGHSFCVQTLLRCGVD 378

Query: 226 LT 227
           + 
Sbjct: 379 VN 384

 Score = 32.7 bits (73), Expect = 0.53,   Method: Compositional matrix adjust.
 Identities = 26/87 (29%), Positives = 39/87 (44%), Gaps = 2/87 (2%)
 Frame = +1

Query: 128 VTAKDL--SKQLHSSVRTGNLETCLRLLSLGAQANFFHPEKGTTPLHVAAKAGQTLQAEL 185
           ++AKD   S  LH +   G+      LL  G   N    +   T +HV++  G+    ++
Sbjct: 280 MSAKDTRGSTPLHLACAHGHSFCVQTLLRCGVDVNSV-DKTSWTSVHVSSYHGRLGCLQM 456

Query: 186 LVVYGADPGSPDVNGRTPIDYARQAGH 212
           L+ +GA     D NG TP   A   GH
Sbjct: 457 LIKWGARYDDIDTNGNTPAHLAAMEGH 537

 Score = 31.6 bits (70), Expect = 1.4,   Method: Compositional matrix adjust.
 Identities = 18/65 (27%), Positives = 29/65 (44%)
 Frame = +1

Query: 147 ETCLRLLSLGAQANFFHPEKGTTPLHVAAKAGQTLQAELLVVYGADPGSPDVNGRTPIDY 206
           E C++ LS    +      +G+TPLH+A   G +   + L+  G D  S D    T +  
Sbjct: 241 EGCIQALSNNGVSMSAKDTRGSTPLHLACAHGHSFCVQTLLRCGVDVNSVDKTSWTSVHV 420

Query: 207 ARQAG 211
           +   G
Sbjct: 421 SSYHG 435

 Score = 30.8 bits (68), Expect = 2.1,   Method: Compositional matrix adjust.
 Identities = 34/125 (27%), Positives = 45/125 (36%), Gaps = 30/125 (24%)
 Frame = +1

Query: 118 HKLPCRDDDGVTAKDLSKQL-----------------------------HSSVRTGNLET 148
           H L  R+D G T +DL++Q                              H +   G L+ 
Sbjct: 583 HTLGARNDHGETPRDLAQQFYKENILEYIDHVQHEMDHPEQAENLAFPAHMAAYNGELDH 762

Query: 149 CLRLLSLGAQANFFH-PEKGTTPLHVAAKAGQTLQAELLVVYGADPGSPDVNGRTPIDYA 207
            LR+L      N     +KG T  H AA  G     + LV  GAD    +  G T  D A
Sbjct: 763 -LRILVENGVVNINERDDKGNTLAHRAAGQGHLNILQWLVEMGADVEISNGAGETARDIA 939

Query: 208 RQAGH 212
           R+  H
Sbjct: 940 RRFAH 954
>20884
          Length = 712

 Score = 33.9 bits (76), Expect = 0.24,   Method: Compositional matrix adjust.
 Identities = 30/114 (26%), Positives = 52/114 (45%), Gaps = 3/114 (2%)
 Frame = +1

Query: 117 VHKLPCRDDDGVTAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFHPEKGT--TPLHVA 174
           + +L  +D+DG         LH S+     +  L+++S+    ++ +       TPLH+A
Sbjct: 160 LEELYSQDEDG------DSYLHMSIIHLLPDVSLKVISVAPSPDYINIPNMLHQTPLHLA 321

Query: 175 AKAGQTLQAELLVVYGADPGSPDVNGRTPIDYARQAGHHELAERLVE-CQYELT 227
               Q      L+V GA   +PD  G T +  A + G  E+ + L+   QY+ T
Sbjct: 322 VATRQMWVVRRLMVAGAAMEAPDYCGNTALHIACREGMTEMVKLLLTPVQYQET 483

 Score = 29.3 bits (64), Expect = 7.1,   Method: Composition-based stats.
 Identities = 19/49 (38%), Positives = 25/49 (51%)
 Frame = +2

Query: 138 HSSVRTGNLETCLRLLSLGAQANFFHPEKGTTPLHVAAKAGQTLQAELL 186
           H +++TG+L     LL  GA  N    + G T LH+AA  G     ELL
Sbjct: 566 HLALQTGHLHILPLLLERGANINEQDGKSGRTLLHMAADLGYLQALELL 712
>36879
          Length = 583

 Score = 33.5 bits (75), Expect = 0.36,   Method: Composition-based stats.
 Identities = 20/53 (37%), Positives = 29/53 (54%)
 Frame = -3

Query: 167 GTTPLHVAAKAGQTLQAELLVVYGADPGSPDVNGRTPIDYARQAGHHELAERL 219
           G TPL +AAK GQ    E L+  GADP +  + G +   +A +    EL +R+
Sbjct: 464 GETPLMLAAKNGQDYVCERLLEAGADPLAIXLQGNSAFXHALEL---ELEQRV 315
>20792
          Length = 441

 Score = 33.1 bits (74), Expect = 0.42,   Method: Composition-based stats.
 Identities = 24/78 (30%), Positives = 34/78 (43%)
 Frame = +2

Query: 135 KQLHSSVRTGNLETCLRLLSLGAQANFFHPEKGTTPLHVAAKAGQTLQAELLVVYGADPG 194
           K LH + + G L+    LL  G Q +        TPL +A    Q     LL+ +GADP 
Sbjct: 83  KPLHETAQFGQLDCMNFLLQRGVQVDCLK-RADWTPLMLACTKCQLPVISLLLKHGADPA 259

Query: 195 SPDVNGRTPIDYARQAGH 212
             + +G      A + GH
Sbjct: 260 LVNKDGWNSFHIAAREGH 313
>16585
          Length = 352

 Score = 32.7 bits (73), Expect = 0.50,   Method: Composition-based stats.
 Identities = 15/29 (51%), Positives = 19/29 (65%)
 Frame = -1

Query: 53  HSAWPPTLLQMVHTLASNGANSIWEHSLL 81
           HS+W  TLL   HTL  N  +S W+H+LL
Sbjct: 244 HSSWQHTLLMATHTLDGN-THS*WQHTLL 161
>02055
          Length = 1740

 Score = 32.7 bits (73), Expect = 0.51,   Method: Compositional matrix adjust.
 Identities = 23/71 (32%), Positives = 30/71 (42%)
 Frame = +3

Query: 137 LHSSVRTGNLETCLRLLSLGAQANFFHPEKGTTPLHVAAKAGQTLQAELLVVYGADPGSP 196
           LH +    N E    L+  GA  N       +TPLHVA +     +  LL+  GA     
Sbjct: 435 LHIATVHANHEAMGALVRNGANVNARAKFLNSTPLHVACRLRGQQEVALLIQLGARIDVN 614

Query: 197 DVNGRTPIDYA 207
           D  G TP+  A
Sbjct: 615 DATGTTPLQMA 647
>15772
          Length = 1282

 Score = 32.3 bits (72), Expect = 0.72,   Method: Compositional matrix adjust.
 Identities = 26/93 (27%), Positives = 39/93 (41%)
 Frame = -3

Query: 137  LHSSVRTGNLETCLRLLSLGAQANFFHPEKGTTPLHVAAKAGQTLQAELLVVYGADPGSP 196
            LH + + G +E C+RLL           + G TP H AA+  +      L          
Sbjct: 1166 LHWACQKGFVE-CIRLLLDHGAKGTARTDTGWTPAHCAAECNRVTALRALHAALVPVDLT 990

Query: 197  DVNGRTPIDYARQAGHHELAERLVECQYELTDR 229
            D  G TP   A   GH + A  L++ + E+ +R
Sbjct: 989  DKYGDTPRRIATLYGHRDCARYLLQAEAEVAER 891
>12886
          Length = 2104

 Score = 31.6 bits (70), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 37/129 (28%), Positives = 57/129 (44%), Gaps = 4/129 (3%)
 Frame = +1

Query: 97  DKVHPIKSEFIRAKYQMLAFVHKLPCRD---DDGVTAKDLSKQLHSSVRTGNLETCLRLL 153
           DKVHP+  E+I AK + L+ V +L C     +DG+  K L    H  ++    E  L L 
Sbjct: 163 DKVHPLIEEYI-AKSESLSKVLRLICIQSICNDGLKPKVLDFYRHEILQVYGFEHMLTLH 339

Query: 154 SLGAQANFFHPEKGTTPLHVAAKAGQTLQAELLVVYGADPGSPDVNGRTPIDYAR-QAGH 212
            L  Q     P          A++ Q L+  L ++        +VN + P D A   +G+
Sbjct: 340 YL-EQVGLLRPH--------GARSYQVLRKSLKLI------VEEVNEQNPSDIAYVYSGY 474

Query: 213 HELAERLVE 221
             L+ RL +
Sbjct: 475 APLSVRLAQ 501
>05396
          Length = 1865

 Score = 31.2 bits (69), Expect = 1.7,   Method: Compositional matrix adjust.
 Identities = 27/93 (29%), Positives = 38/93 (40%), Gaps = 3/93 (3%)
 Frame = +3

Query: 143  TGNLETCLRLLSLGAQANFFHPEKGTTPLHVAAKAGQTLQAELLVVYGADPGSPDVNGRT 202
            T  L+ C+R + L  QAN          L  +A  G         + G D   PD +GRT
Sbjct: 1236 TRKLDPCVRHMEL--QAN------RIVDLLFSAYNGDVTAIRRCALSGMDMSQPDYDGRT 1391

Query: 203  PIDYARQAGHHELAERLVE---CQYELTDRLAF 232
             +  A   G  ++ E L++   C   L DR  F
Sbjct: 1392 ALHVASAEGQLQVVEFLLDRCKCSPFLVDRWGF 1490
>17893
          Length = 453

 Score = 29.6 bits (65), Expect = 5.2,   Method: Composition-based stats.
 Identities = 23/73 (31%), Positives = 32/73 (43%)
 Frame = -3

Query: 132 DLSKQLHSSVRTGNLETCLRLLSLGAQANFFHPEKGTTPLHVAAKAGQTLQAELLVVYGA 191
           D++   H   +  NL+    LL  GA  N      G T LH AA+A        L+ +G 
Sbjct: 220 DMADSPHEEAKI-NLDFVDSLLKNGASINIMD-RTGQTLLHEAARAWHVDVTRWLLDHGI 47

Query: 192 DPGSPDVNGRTPI 204
           +   PD  GRT +
Sbjct: 46  NIDQPDYYGRTAL 8
>15359
          Length = 780

 Score = 29.3 bits (64), Expect = 6.1,   Method: Compositional matrix adjust.
 Identities = 25/76 (32%), Positives = 35/76 (46%), Gaps = 2/76 (2%)
 Frame = +1

Query: 137 LHSSVRTGNLETCLRLLS-LGAQANFFHPEKGTTPLHVAAKAGQTLQAELLVV-YGADPG 194
           LH + + G  E    L + +G + N      G TPLH+AA  G     ELLV  Y AD  
Sbjct: 361 LHWAAKFGKPEVVKMLANKIGVEINQ-RSHGGYTPLHLAAIHGHEDIIELLVTGYKADAN 537

Query: 195 SPDVNGRTPIDYARQA 210
             D +G+    Y + +
Sbjct: 538 IRDYSGKKAKQYLKNS 585
>25464
          Length = 440

 Score = 28.9 bits (63), Expect = 7.2,   Method: Compositional matrix adjust.
 Identities = 17/52 (32%), Positives = 23/52 (44%)
 Frame = -3

Query: 192 DPGSPDVNGRTPIDYARQAGHHELAERLVECQYELTDRLAFYLCGRKPDHKN 243
           D   PD +G TPI +A  + +  +   L E         AFY  G  PD +N
Sbjct: 333 DINEPDNDGNTPIHHAAISANPNIVRMLAE---------AFYKFGLNPDKRN 205
>28113
          Length = 449

 Score = 28.5 bits (62), Expect = 9.4,   Method: Compositional matrix adjust.
 Identities = 26/75 (34%), Positives = 34/75 (45%), Gaps = 1/75 (1%)
 Frame = -3

Query: 137 LHSSVRTGNLETCLRLLSLGAQANFFHPEKGTTPLHVAAKAGQTLQAELLVVYGA-DPGS 195
           +H +   G+ +    LL  G   N  + E   TPLH+AAK G    AE LV   A D   
Sbjct: 222 IHYASWYGSADVVEILLDAGCSPNLTNSEL-LTPLHIAAKKGFPDVAEHLVQAEAIDLNL 46

Query: 196 PDVNGRTPIDYARQA 210
            D +G+  ID    A
Sbjct: 45  RDKDGKRAIDICTSA 1
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|25023734|ref|XP_203592.1| PREDICTED: HESB like domain
containing 1 isoform 1 [Mus musculus]
         (154 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

00806                                                                 111   1e-25
09698                                                                  82   1e-16
>00806
          Length = 1952

 Score =  111 bits (278), Expect = 1e-25,   Method: Compositional matrix adjust.
 Identities = 49/73 (67%), Positives = 63/73 (86%)
 Frame = +1

Query: 82  FQYKFSLDTVINPDDRVFEQGGARVVVDSDSLAFVKGAQVDFSQELIRSSFQVLNNPQAQ 141
           FQYKF LDT +  DDRVFE+ GARVV+D DSL +VKG+ VDF QELIRS+F++++NP A+
Sbjct: 328 FQYKFELDTEVGEDDRVFEKDGARVVIDKDSLDYVKGSTVDFYQELIRSAFRIVDNPLAE 507

Query: 142 QGCSCGSSFSVKV 154
           QGCSCG+SFS+K+
Sbjct: 508 QGCSCGASFSIKL 546
>09698
          Length = 412

 Score = 81.6 bits (200), Expect = 1e-16,   Method: Compositional matrix adjust.
 Identities = 35/54 (64%), Positives = 48/54 (88%)
 Frame = -1

Query: 101 QGGARVVVDSDSLAFVKGAQVDFSQELIRSSFQVLNNPQAQQGCSCGSSFSVKV 154
           + GARVV+D DSL +VKG+ VDF QELIRS+F++++NP A+QGCSCG+SFS+K+
Sbjct: 382 KDGARVVIDRDSLDYVKGSTVDFYQELIRSAFRIVDNPLAEQGCSCGASFSIKL 221
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|63712148|ref|XP_283480.3| PREDICTED: hypothetical
protein LOC320473 isoform 1 [Mus musculus]
         (2070 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

30334                                                                  84   1e-25
05976                                                                  31   4.3  
02545                                                                  30   7.8  
>30334
          Length = 834

 Score = 83.6 bits (205), Expect(2) = 1e-25,   Method: Compositional matrix adjust.
 Identities = 45/126 (35%), Positives = 73/126 (57%), Gaps = 1/126 (0%)
 Frame = +2

Query: 1855 DEVSTLTAIALFLWSASSEIIGVQSLQNGCMNRFKSALNSCDPWVQAKCYQLLLSVFQHS 1914
            DE   + A+ +F+ S   E  G  +LQ   ++ F+ A ++ +  V+ KC Q  +S+ QHS
Sbjct: 5    DEGVLVEALTVFIVSCPRETTGAANLQEPVLDCFRDAWDTNNFEVRLKCVQSFISIVQHS 184

Query: 1915 NRALSTPYIHSLAPLVVGKLKAVERH-RPASSTELLAVQEGIKVLETLVALGEEQNRVQL 1973
            +R ++ P+IH LAP ++  L A      P S  +L    E + ++ETLVAL E+  RV +
Sbjct: 185  DRQVAPPFIHGLAPRMMEHLHATASSASPPSDNDLQLTLEELTMMETLVALAEDNKRVTM 364

Query: 1974 LALLVP 1979
            +ALL+P
Sbjct: 365  VALLIP 382

 Score = 53.9 bits (128), Expect(2) = 1e-25,   Method: Compositional matrix adjust.
 Identities = 27/60 (45%), Positives = 38/60 (63%)
 Frame = +3

Query: 1979 PTLISYLLDENSFASASSISKDLHEFALQNLMHIGPLYPHAFKTVMGAAPELKARLETAV 2038
            P L+S LLDEN+ A+A++  + L + AL  L+ +G  Y   FK VMGA+  L+ RL  AV
Sbjct: 381  PILVSLLLDENTAATANANRRSLSDTALSKLLRLGQQYTDHFKQVMGASAHLRPRLAAAV 560
>05976
          Length = 1631

 Score = 31.2 bits (69), Expect = 4.3,   Method: Compositional matrix adjust.
 Identities = 18/51 (35%), Positives = 26/51 (50%)
 Frame = +3

Query: 1691 ESCPTLGEGGDTGGLIPGKSLVFATMELLMFILVRHMPHLSTKMLDSPSHT 1741
            +SCP       TG L PG  L  +    L+F+LV+H  H +  ++  PS T
Sbjct: 210  KSCPATEA---TGPLSPGSPLPRSITPPLLFLLVQHKSHCTVGLVQQPSST 353
>02545
          Length = 1281

 Score = 30.4 bits (67), Expect = 7.8,   Method: Composition-based stats.
 Identities = 14/33 (42%), Positives = 19/33 (57%)
 Frame = +2

Query: 1531 ILHAVALWLNSTGFISQESTEATTVSGVQKRSP 1563
            IL+  + WL+  G     STEAT V G+  +SP
Sbjct: 689  ILYVDSSWLDHLGRRRNHSTEATVVCGINSKSP 787
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|75677414|ref|NP_031829.2| cortactin [Mus musculus]
         (546 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

16716                                                                 114   1e-25
15115                                                                  70   3e-12
31183                                                                  67   1e-11
12324                                                                  64   2e-10
28095                                                                  52   4e-07
01494                                                                  51   1e-06
17286                                                                  50   3e-06
29687                                                                  48   1e-05
19469                                                                  41   0.001
26032                                                                  41   0.002
20131                                                                  40   0.002
13664                                                                  36   0.035
33143                                                                  35   0.055
31680                                                                  33   0.25 
11228                                                                  32   0.77 
36643                                                                  32   0.81 
30482                                                                  30   2.0  
29243                                                                  30   3.2  
11780                                                                  28   9.1  
>16716
          Length = 934

 Score =  114 bits (285), Expect = 1e-25,   Method: Compositional matrix adjust.
 Identities = 54/97 (55%), Positives = 68/97 (70%), Gaps = 11/97 (11%)
 Frame = -1

Query: 461 TSEPVYETTEAPG-HYQAEDDTYDGYESDL----------GITAIALYDYQAAGDDEISF 509
           +SE  YE +E P   ++ E+  Y+  + +           G TAIALYDYQAA DDE++F
Sbjct: 592 SSENPYEVSEEPAPQHEPEESPYEMADEEPAAPAQSQPGGGSTAIALYDYQAADDDELTF 413

Query: 510 DPDDIITNIEMIDDGWWRGVCKGRYGLFPANYVELRQ 546
           DPDD+IT+IEMIDDGWWRG C G+ GLFPANYVEL+Q
Sbjct: 412 DPDDVITDIEMIDDGWWRGSCHGKNGLFPANYVELQQ 302
>15115
          Length = 443

 Score = 69.7 bits (169), Expect = 3e-12,   Method: Compositional matrix adjust.
 Identities = 32/47 (68%), Positives = 38/47 (80%), Gaps = 1/47 (2%)
 Frame = -2

Query: 499 YQAAGDDEISFDPDDIITNIEMIDDGWWRGVCK-GRYGLFPANYVEL 544
           +QA  D EI+FDPDDIITNI+ ID+GWW+G    G YG+FPANYVEL
Sbjct: 433 HQAGDDTEITFDPDDIITNIDQIDEGWWQGFAPDGSYGMFPANYVEL 293
>31183
          Length = 923

 Score = 67.4 bits (163), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 28/35 (80%), Positives = 32/35 (91%)
 Frame = +1

Query: 512 DDIITNIEMIDDGWWRGVCKGRYGLFPANYVELRQ 546
           DD+IT+IEMIDDGWWRG C G+ GLFPANYVEL+Q
Sbjct: 1   DDVITDIEMIDDGWWRGSCHGKNGLFPANYVELQQ 105
>12324
          Length = 946

 Score = 63.9 bits (154), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 27/51 (52%), Positives = 35/51 (68%)
 Frame = +3

Query: 493 AIALYDYQAAGDDEISFDPDDIITNIEMIDDGWWRGVCKGRYGLFPANYVE 543
            +A+YDY+A  DDE++F  + +I  I   DDGWW GV  G  GLFP+NYVE
Sbjct: 696 VVAIYDYEAEKDDELTFSENSVIYVIRKNDDGWWEGVMDGVTGLFPSNYVE 848
>28095
          Length = 597

 Score = 52.4 bits (124), Expect = 4e-07,   Method: Compositional matrix adjust.
 Identities = 26/56 (46%), Positives = 36/56 (64%), Gaps = 2/56 (3%)
 Frame = +3

Query: 490 GITAIALYDYQAAGDDEISFDPDDIITNIEMIDDGWWRGVCK--GRYGLFPANYVE 543
           G+   A+YDYQAA  DE+SF+  D I   + +D GW  G  +  G+YG+ P+NYVE
Sbjct: 255 GMVCKAMYDYQAADSDEVSFNDGDTIIECQPVDAGWMTGRVERTGQYGMLPSNYVE 422
>01494
          Length = 2122

 Score = 50.8 bits (120), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 31/76 (40%), Positives = 39/76 (51%), Gaps = 5/76 (6%)
 Frame = +3

Query: 473 GHYQAEDDTYDGYESDLGITAIALYDYQAAGDDEISFDPDDIITNIEMIDDGWWRGVCKG 532
           G Y A D   +  +    +   AL+DY A  DDE+SF    IITN+   D GWWR    G
Sbjct: 252 GIYGAPDVYINPNDFTTKLRVKALHDYNANRDDELSFCKGAIITNVSRQDGGWWR----G 419

Query: 533 RYG-----LFPANYVE 543
            YG      FP+N+VE
Sbjct: 420 DYGAKKQHWFPSNFVE 467
>17286
          Length = 489

 Score = 49.7 bits (117), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 22/53 (41%), Positives = 31/53 (58%)
 Frame = +3

Query: 492 TAIALYDYQAAGDDEISFDPDDIITNIEMIDDGWWRGVCKGRYGLFPANYVEL 544
            A A+YD+    D E+ F   D+IT I  +D+ W+ G   G+ G FP NYVE+
Sbjct: 27  CARAIYDFLPESDGELGFQEGDMITLISQVDENWFEGSVHGKVGYFPINYVEV 185
>29687
          Length = 434

 Score = 48.1 bits (113), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 27/54 (50%), Positives = 32/54 (59%), Gaps = 5/54 (9%)
 Frame = -2

Query: 495 ALYDYQAAGDDEISFDPDDIITNIEMIDDGWWRGVCKGRYG-----LFPANYVE 543
           AL+DY A  +DE+SF    IITN+   D GWWR    G YG      FP+NYVE
Sbjct: 286 ALHDYNAKREDELSFCKGAIITNVSRQDGGWWR----GDYGTKKQHWFPSNYVE 137
>19469
          Length = 428

 Score = 41.2 bits (95), Expect = 0.001,   Method: Composition-based stats.
 Identities = 22/55 (40%), Positives = 31/55 (56%), Gaps = 3/55 (5%)
 Frame = -1

Query: 493 AIALYDYQAAGDDEISFDPDDIITNIEMID---DGWWRGVCKGRYGLFPANYVEL 544
           A ALYD  A   DE++F   D+IT +E      DGWW    +GR G+ P N +++
Sbjct: 359 AKALYDNIAETPDELAFRRGDVITILEQDTAGLDGWWLCSLRGRQGIAPGNRLKI 195
>26032
          Length = 465

 Score = 40.8 bits (94), Expect = 0.002,   Method: Composition-based stats.
 Identities = 20/47 (42%), Positives = 27/47 (57%)
 Frame = +2

Query: 498 DYQAAGDDEISFDPDDIITNIEMIDDGWWRGVCKGRYGLFPANYVEL 544
           D++   DDE+ F  +DIIT I   D+  W G   G  G FPA +VE+
Sbjct: 29  DFERHDDDELGFRKNDIITLISQKDEHCWIGELNGLRGWFPAKFVEV 169
>20131
          Length = 574

 Score = 40.4 bits (93), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 18/56 (32%), Positives = 30/56 (53%), Gaps = 5/56 (8%)
 Frame = -2

Query: 493 AIALYDYQAAGDDEISFDPDDIITNIEMIDDGWWRGVCKGR-----YGLFPANYVE 543
           A+ +  Y A G+ ++S +P ++I   +    GWW G  + R      G FPA+YV+
Sbjct: 276 AMVIAPYTATGNGQLSLEPGNLIHVRQKSPRGWWEGELQARGQRKKIGWFPADYVK 109

 Score = 38.9 bits (89), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 15/50 (30%), Positives = 29/50 (58%)
 Frame = -2

Query: 494 IALYDYQAAGDDEISFDPDDIITNIEMIDDGWWRGVCKGRYGLFPANYVE 543
           +A+Y Y +    +++F+  D+I  +   D+ WW G    + G+FP+ YV+
Sbjct: 471 VAMYSYVSGETADLTFNEGDMIL-VTKKDEDWWTGTLGEKTGMFPSTYVK 325
>13664
          Length = 507

 Score = 36.2 bits (82), Expect = 0.035,   Method: Compositional matrix adjust.
 Identities = 17/49 (34%), Positives = 26/49 (53%), Gaps = 5/49 (10%)
 Frame = +2

Query: 485 YESDLGIT-----AIALYDYQAAGDDEISFDPDDIITNIEMIDDGWWRG 528
           ++S LG T      +ALYDY+A   DE++    D+I  +    + WW G
Sbjct: 332 FQSPLGSTRKPKKVVALYDYKAQRSDELTILSGDVIMLLHKDSESWWMG 478
>33143
          Length = 1469

 Score = 35.4 bits (80), Expect = 0.055,   Method: Compositional matrix adjust.
 Identities = 21/56 (37%), Positives = 27/56 (48%), Gaps = 3/56 (5%)
 Frame = -2

Query: 492 TAIALYDYQAAGDDEISFDPDDIITNIEMIDD---GWWRGVCKGRYGLFPANYVEL 544
            A A+  Y A   DEIS    D ++ I+M       WWRG      G FPA+ VE+
Sbjct: 433 AAHAVKPYAAHASDEISLQVGDFVSVIDMPSSEGTKWWRGKKGFEVGFFPADCVEV 266
>31680
          Length = 388

 Score = 33.5 bits (75), Expect = 0.25,   Method: Composition-based stats.
 Identities = 27/85 (31%), Positives = 37/85 (43%), Gaps = 8/85 (9%)
 Frame = +2

Query: 403 PASPSPQPIEDRPPSSPIYEDAAPFKAEPSYRGS---EPEPEYSIEAAGIPEAGSQQGLT 459
           P    P+P   +P   P+Y     +KAEP Y+     +PEP Y+   +  P    Q   T
Sbjct: 134 PRGIRPRPSYHKPEPKPVYHPKPVYKAEPVYKAEPVYKPEPVYT---SPKPIYHPQPLYT 304

Query: 460 -----YTSEPVYETTEAPGHYQAED 479
                Y  EPVY TT  P ++   D
Sbjct: 305 TPKPVYHPEPVY-TTPKPVYHPKTD 376
>11228
          Length = 2155

 Score = 31.6 bits (70), Expect = 0.77,   Method: Compositional matrix adjust.
 Identities = 18/54 (33%), Positives = 28/54 (51%), Gaps = 3/54 (5%)
 Frame = -2

Query: 493  AIALYDYQAAGD-DEISFDPDDIITNIEMIDDGWWRGVCK--GRYGLFPANYVE 543
             +A+  Y+ A D DE+SF   D+      ++DGW    C+     GL PA +V+
Sbjct: 1665 VVAMLSYRKATDSDELSFCKGDVFVVQNEMEDGWLWVTCERTKESGLVPAPFVK 1504
>36643
          Length = 601

 Score = 31.6 bits (70), Expect = 0.81,   Method: Compositional matrix adjust.
 Identities = 18/71 (25%), Positives = 35/71 (49%), Gaps = 4/71 (5%)
 Frame = +1

Query: 478 EDDTYDGYESDLGITAIALYDYQAAGDDEISFDPDDIIT----NIEMIDDGWWRGVCKGR 533
           E++++   E+D  + A  L+ +   G++E+SF     +      ++    GW      GR
Sbjct: 154 EEESWAKGETD-HVVAQTLFSFTGQGEEELSFSAGQQLILAPKEVQPQVRGWLLASVGGR 330

Query: 534 YGLFPANYVEL 544
            GL P NY+++
Sbjct: 331 KGLVPYNYIKI 363
>30482
          Length = 610

 Score = 30.4 bits (67), Expect = 2.0,   Method: Compositional matrix adjust.
 Identities = 15/33 (45%), Positives = 21/33 (63%)
 Frame = +3

Query: 490 GITAIALYDYQAAGDDEISFDPDDIITNIEMID 522
           G+ A ALY ++A  D+ +SF+ DDII   E  D
Sbjct: 507 GLKAQALYQWKARQDNHLSFNKDDIIVVKEQED 605
>29243
          Length = 1147

 Score = 29.6 bits (65), Expect = 3.2,   Method: Compositional matrix adjust.
 Identities = 14/36 (38%), Positives = 19/36 (52%)
 Frame = +3

Query: 507 ISFDPDDIITNIEMIDDGWWRGVCKGRYGLFPANYV 542
           + FD D ++  I   D  W RG   G  G FP++YV
Sbjct: 54  LCFDKDHVVDVISDADTEWCRGRFNGEEGYFPSSYV 161
>11780
          Length = 1713

 Score = 28.1 bits (61), Expect = 9.1,   Method: Compositional matrix adjust.
 Identities = 14/40 (35%), Positives = 19/40 (47%), Gaps = 2/40 (5%)
 Frame = +3

Query: 509 FDPDDIITNIEMIDDGWWRGVC--KGRYGLFPANYVELRQ 546
           F   D++       D  W   C   GR G+ PANYV+ R+
Sbjct: 111 FQKGDLLVIRRATSDRMWYKACDSNGREGMIPANYVQPRK 230
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|100818161|ref|NP_001035780.1| RAP1, GTP-GDP
dissociation stimulator 1 isoform a [Mus musculus]
         (607 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

20715                                                                 113   2e-25
34479                                                                  33   0.45 
14069                                                                  33   0.47 
29610                                                                  31   1.6  
29389                                                                  30   2.9  
22653                                                                  29   5.4  
>20715
          Length = 767

 Score =  113 bits (283), Expect = 2e-25,   Method: Compositional matrix adjust.
 Identities = 54/113 (47%), Positives = 76/113 (67%)
 Frame = +1

Query: 396 AKMLSAGVTETVLKFLKSEMPPVQFKLLGTLRMLIDAQAEAAEQLGKNAKLVERLVEWCE 455
            ++L  GV   VL    +E+  V FKLLG LRMLID Q  AA  LG+    +  LV+WC 
Sbjct: 1   GRLLELGVMTAVLDIKHTEVMAVTFKLLGVLRMLIDGQETAATSLGQEKDFLNCLVDWCA 180

Query: 456 AKDHAGVMGESNRLLSALIRHSKSKDVIKTIVQSGGIKHLVTMATSEHVIMQN 508
             +HAGV GE+ RL++ +I++SK+  V + +V++ G++HLVTMATSEH +MQN
Sbjct: 181 VDEHAGVKGEATRLMAWIIKNSKASQVTRNMVRAEGMQHLVTMATSEHTVMQN 339
>34479
          Length = 414

 Score = 32.7 bits (73), Expect = 0.45,   Method: Compositional matrix adjust.
 Identities = 15/39 (38%), Positives = 25/39 (64%)
 Frame = +3

Query: 94  LVQLLNSKDQEVLLQTGRALGNICYDSHEGRSAVDQAGG 132
           L+QLL SK++E+ L  G AL    +++   + A+ +AGG
Sbjct: 153 LLQLLRSKNEEIRLHAGMALTIFAFNNTPQQFAIREAGG 269
>14069
          Length = 463

 Score = 32.7 bits (73), Expect = 0.47,   Method: Compositional matrix adjust.
 Identities = 14/29 (48%), Positives = 21/29 (72%)
 Frame = +3

Query: 64  CTAKVADIIAEVAKNEFMRIPCVDAGLIS 92
            TAK A +IAE+AK E +R+P V+ G++ 
Sbjct: 345 ITAKAAQVIAELAKAETVRVPLVNLGVVP 431
>29610
          Length = 904

 Score = 30.8 bits (68), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 18/60 (30%), Positives = 32/60 (53%)
 Frame = +1

Query: 63  SCTAKVADIIAEVAKNEFMRIPCVDAGLISPLVQLLNSKDQEVLLQTGRALGNICYDSHE 122
           +CT    ++ A+ ++  F+++ CVD GLISP    L + +  +L      L ++ Y  HE
Sbjct: 526 TCTTPETEVAAQASR--FIQLQCVDIGLISPRRSKL*NGNFYMLGMMQLGLESMAYSIHE 699
>29389
          Length = 1070

 Score = 30.0 bits (66), Expect = 2.9,   Method: Compositional matrix adjust.
 Identities = 21/71 (29%), Positives = 38/71 (53%), Gaps = 2/71 (2%)
 Frame = +2

Query: 34  LAQNNAETSEKIQGSGILQLFANLLT-PQASCTAKVADIIAEVAKNEFMRIPCV-DAGLI 91
           +   N   ++ +  SG LQ+F+ LL  P+AS   + A  ++ +      +I  V DAGL+
Sbjct: 5   IVTGNDTQTQVVLDSGALQVFSYLLRHPKASLQKEAAWTLSNITAGNRDQIQAVIDAGLV 184

Query: 92  SPLVQLLNSKD 102
             L++L++  D
Sbjct: 185 PLLIELMHRGD 217
>22653
          Length = 1347

 Score = 29.3 bits (64), Expect = 5.4,   Method: Compositional matrix adjust.
 Identities = 14/60 (23%), Positives = 32/60 (53%)
 Frame = +3

Query: 313 GKGSVFQRVLSWIPSNNHQLQLAGALAIANFARNDGNCIHMVDNGIVEKLMDLLDRHVED 372
           GK +    ++ ++ S +  +  + A A+   ++N  NCI M + G+V+ L+ ++    +D
Sbjct: 354 GKENAVAPLVRYLKSKDENVHRSTARALFQLSKNPENCITMHEAGVVQPLLKMVGSADDD 533

 Score = 28.9 bits (63), Expect = 6.8,   Method: Compositional matrix adjust.
 Identities = 22/70 (31%), Positives = 31/70 (44%), Gaps = 1/70 (1%)
 Frame = +3

Query: 45  IQGSGILQLFANL-LTPQASCTAKVADIIAEVAKNEFMRIPCVDAGLISPLVQLLNSKDQ 103
           I   G++ + A L LT        +A+ IA        R        ++PLV+ L SKD+
Sbjct: 228 ITDHGVVPMLAKLTLTTDDKLRQHLAEAIARCCNWGNNRTAFGKENAVAPLVRYLKSKDE 407

Query: 104 EVLLQTGRAL 113
            V   T RAL
Sbjct: 408 NVHRSTARAL 437
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|114205428|ref|NP_036122.2| reticulocalbin 2 [Mus
musculus]
         (320 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

07198                                                                  90   2e-25
11230                                                                  82   2e-23
08380                                                                 100   6e-22
15239                                                                  75   5e-14
03627                                                                  33   0.14 
00167                                                                  32   0.25 
26019                                                                  32   0.37 
14594                                                                  32   0.38 
32088                                                                  32   0.39 
13551                                                                  31   0.54 
17484                                                                  31   0.67 
01773                                                                  29   2.4  
15966                                                                  28   3.4  
14601                                                                  28   3.5  
11270                                                                  28   3.7  
05237                                                                  28   5.8  
39823                                                                  27   8.7  
08108                                                                  27   9.9  
>07198
          Length = 1675

 Score = 90.1 bits (222), Expect(2) = 2e-25,   Method: Compositional matrix adjust.
 Identities = 83/244 (34%), Positives = 127/244 (52%), Gaps = 16/244 (6%)
 Frame = -3

Query: 83  FLTENELSQWIQMSFKHYAMQEAKQQFVEYDKNSDGAVTWDEYNIQMYD-RVIDFDE--- 138
           F  + E+  WI  SF+    +EA ++F E D++ DG VTWDEY  ++Y    +D DE   
Sbjct: 731 FHHQKEMHDWIVESFQSLDREEAAERFEEEDEDKDGKVTWDEYLDKVYGFNKLDVDEMQK 552

Query: 139 --NTALD---DTEEGSFRQLHL--KDKKRFEKANQDSGPGLSLEEFIAFEHPEEVDYMTE 191
             N A D   D  + +   L L  +D+K F+ A+ +    L+ +E+ AF  P   +   +
Sbjct: 551 SVNEAKDKNTDEFKENVNNLELVDEDRKVFDAADANKDGSLNSKEYFAFFMP---NSFPQ 381

Query: 192 FVIQEALEEHDKNGDGFVSLEEFL-----GDYRRDPTANEDPEWILVEKDRFVNDYDKDN 246
             ++  + + DKN DG +S+EEF+     GD R   T++E+             +YDKD 
Sbjct: 380 LELERFMRQSDKNKDGTISMEEFMPEGATGDTR---TSSEES----------FKNYDKDK 240

Query: 247 DGRLDPQELLSWVVPNNQGIAQEEALHLIDEMDLNSDKKLSEEEILENQDLFLTSEATDY 306
           DG L  +E + W+ P++   A  E  HL    D+N D KLS++EIL   D F+ S ATDY
Sbjct: 239 DGSLSLEEAMEWINPSSDEHADVEVEHLFTIGDVNHDGKLSKDEILNKADQFVGSAATDY 60

Query: 307 GRQL 310
           G  +
Sbjct: 59  GNLI 48

 Score = 43.1 bits (100), Expect(2) = 2e-25,   Method: Compositional matrix adjust.
 Identities = 21/59 (35%), Positives = 35/59 (59%)
 Frame = -1

Query: 32  HYPQGEHRADYDREALLGVQEDVDEYVKLGHEEQQRRLQSIIKKIDSDSDGFLTENELS 90
           H   GEH  DYD +++LG +   D++  L  EE + RL++++ K D D D F+T+ + +
Sbjct: 883 HTADGEHNPDYDHQSILGSEALDDDFEGLSPEEAKXRLZNLVXKHDRDBDNFITKRKCT 707
>11230
          Length = 747

 Score = 82.4 bits (202), Expect(2) = 2e-23,   Method: Compositional matrix adjust.
 Identities = 49/117 (41%), Positives = 74/117 (63%), Gaps = 4/117 (3%)
 Frame = +3

Query: 202 DKNGDGFVSLEEFLGD-YRRDPTANEDPEWILVEKDRFVNDYDKDNDGRLDPQELLSWVV 260
           DK+ DG + LEE++ D +      +E+P+W+  E+ +F    D D DG+LDP E+  W++
Sbjct: 270 DKDKDGLIDLEEYIADMWPNRDNEDEEPDWVKSERKQFDTYRDLDKDGKLDPSEVKRWIL 449

Query: 261 PNNQGIAQEEALHLIDEMD-LNSDKKLSEEEILENQDLFLTSEATDYGRQL--HDDY 314
           P N   A+ E+ HLI E D  + D KLS +EIL+  DLF+ S+ATD+G  L  HD++
Sbjct: 450 PENFDHARAESKHLIFEADGGDKDGKLSYDEILDKYDLFVGSQATDFGEALTRHDEF 620

 Score = 44.3 bits (103), Expect(2) = 2e-23,   Method: Compositional matrix adjust.
 Identities = 23/63 (36%), Positives = 40/63 (63%)
 Frame = +1

Query: 137 DENTALDDTEEGSFRQLHLKDKKRFEKANQDSGPGLSLEEFIAFEHPEEVDYMTEFVIQE 196
           D NT    TE  ++ ++  +D++R+EKA+ +    LS EEF+ F HPE+ ++M + V+ E
Sbjct: 82  DPNTKGSRTE--AYAEMINRDRRRWEKADHNKDNRLSKEEFMDFLHPEDAEHMRDIVVME 255

Query: 197 ALE 199
            +E
Sbjct: 256 TVE 264
>08380
          Length = 1236

 Score =  100 bits (250), Expect = 6e-22,   Method: Compositional matrix adjust.
 Identities = 74/270 (27%), Positives = 132/270 (48%), Gaps = 21/270 (7%)
 Frame = -1

Query: 66  QRRLQSIIKKIDSDSDGFLTENELSQWIQMSFKHY---AMQEAKQQFVEYDKNSDGAVTW 122
           + +L+ I+ K+DSD DG L+  EL  W++   + +   A QE ++ F   D +++G V W
Sbjct: 888 ESKLKDIVYKVDSDKDGKLSVAELEAWVKDKMEEHFSEATQENEEIFKHLDPDNNGKVHW 709

Query: 123 DEYNIQMY-----------DRVIDFDENTALDDTEEGSFRQLHLKDKKRFEKANQDSGPG 171
            EY +                V+D+DZ     D +E   R        +F  ++ D  P 
Sbjct: 708 KEYYVHFLLAKGYKQDVASRHVVDYDZIQLDPDAKEEIIRY-------KFRWSDADGEPM 550

Query: 172 ---LSLEEFIAFEHPEEVDYMTEFVIQEALEEHDKNGDGFVSLEEF----LGDYRRDPTA 224
              L+ EEF++F HPE+ +     ++   L   D NGDG V+ EEF     G+   +   
Sbjct: 549 DNELTREEFMSFRHPEQSEKTLNNMVNGILGGIDTNGDGVVTEEEFSALPPGEVEGEEYQ 370

Query: 225 NEDPEWILVEKDRFVNDYDKDNDGRLDPQELLSWVVPNNQGIAQEEALHLIDEMDLNSDK 284
             D +W    ++ F    D D+DG++   E+  ++ P N   A  EA  L+  MD + D 
Sbjct: 369 AMDKQWQKERQEEFRTAIDLDHDGKVTKDEIKKYMDPRNPLQALLEAKSLVSYMDDDKDG 190

Query: 285 KLSEEEILENQDLFLTSEATDYGRQLHDDY 314
            +S+ E++ ++D+F++S+  ++   +HD++
Sbjct: 189 MISQAEVMRHKDIFISSKVMNFAANVHDEF 100
>15239
          Length = 913

 Score = 74.7 bits (182), Expect = 5e-14,   Method: Compositional matrix adjust.
 Identities = 38/88 (43%), Positives = 59/88 (67%), Gaps = 2/88 (2%)
 Frame = +2

Query: 229 EWILVEKDRFVNDYDKDNDGRLDPQELLSWVVPNNQGIAQEEALHLIDEMDLNSDKKLSE 288
           +W+  E+D+F    DK+NDG+LD  E+  W++P++   +  EA HLI + D + D KLS 
Sbjct: 2   DWVRSERDQFQQFRDKNNDGKLDANEVREWIIPDDYDHSSAEAKHLIGDSDGDKDGKLSY 181

Query: 289 EEILENQDLFLTSEATDYGRQL--HDDY 314
           +EIL+  DLF+ S+ATD+G  L  HD++
Sbjct: 182 DEILDKYDLFVGSQATDFGEALTRHDEF 265

 Score = 30.4 bits (67), Expect = 1.0,   Method: Compositional matrix adjust.
 Identities = 20/66 (30%), Positives = 35/66 (53%), Gaps = 4/66 (6%)
 Frame = +2

Query: 77  DSDSDGFLTENELSQWIQMSFKHYAMQEAKQQFVEYDKNSDGAVTWDE----YNIQMYDR 132
           D ++DG L  NE+ +WI      ++  EAK    + D + DG +++DE    Y++ +  +
Sbjct: 44  DKNNDGKLDANEVREWIIPDDYDHSSAEAKHLIGDSDGDKDGKLSYDEILDKYDLFVGSQ 223

Query: 133 VIDFDE 138
             DF E
Sbjct: 224 ATDFGE 241
>03627
          Length = 1099

 Score = 33.1 bits (74), Expect = 0.14,   Method: Compositional matrix adjust.
 Identities = 28/119 (23%), Positives = 57/119 (47%), Gaps = 14/119 (11%)
 Frame = +1

Query: 57  YVKLGHEEQQRRLQSIIKKIDSD----------SDGFLTENELSQWIQMS----FKHYAM 102
           ++K+G  +Q ++ + + +   SD          +DG      + +W   +    +K+   
Sbjct: 244 HLKVGSGKQAKKFRGVREGTISDNTSYYIFTQCADGAFEAFPVREWYNFTPMIRYKYLNS 423

Query: 103 QEAKQQFVEYDKNSDGAVTWDEYNIQMYDRVIDFDENTALDDTEEGSFRQLHLKDKKRF 161
            EA+++F   DK      T + +NI +  RV + D++T LDD E+ + ++L    K+R 
Sbjct: 424 DEAEEEFSRRDK------TLNYFNIMLKKRVKNEDKDTELDDEEKAAKKKLPNPRKQRL 582
>00167
          Length = 2176

 Score = 32.3 bits (72), Expect = 0.25,   Method: Compositional matrix adjust.
 Identities = 27/86 (31%), Positives = 38/86 (44%)
 Frame = +3

Query: 172 LSLEEFIAFEHPEEVDYMTEFVIQEALEEHDKNGDGFVSLEEFLGDYRRDPTANEDPEWI 231
           LS++EFI       +  MT   + E     DK+G G +  EEFL   R  P  NE    +
Sbjct: 780 LSVDEFIVGCRECRIAKMTSEELNEVFRRFDKDGTGTLDFEEFLLALR--PKMNEFRRKL 953

Query: 232 LVEKDRFVNDYDKDNDGRLDPQELLS 257
           +  K  F    DK  DG +   +L+ 
Sbjct: 954 V--KKAFAK-MDKTGDGIITADDLVG 1022
>26019
          Length = 1561

 Score = 32.0 bits (71), Expect = 0.37,   Method: Compositional matrix adjust.
 Identities = 32/109 (29%), Positives = 52/109 (47%), Gaps = 4/109 (3%)
 Frame = +2

Query: 159 KRFEKANQDSGPGLSLEEFIAFEHPEEVDYMTEFVIQEALEEHDKNGDGFVSLEEFLGDY 218
           KRF K + D+   LS++EF++    ++       ++Q  ++  D +G+G V  +EF+   
Sbjct: 110 KRFRKLDLDNSGSLSIDEFMSLPELQQ-----NPLVQRVIDIFDTDGNGEVDFKEFIEGI 274

Query: 219 RRDPTANEDPEWILVEKDRFV-NDYDKDNDGRLDPQEL---LSWVVPNN 263
            +  +   D E     K RF    YD D DG +   EL   L  +V NN
Sbjct: 275 SQ-FSVKGDKE----SKLRFAFKIYDMDKDGYISNGELFQVLKMMVGNN 406
>14594
          Length = 1014

 Score = 32.0 bits (71), Expect = 0.38,   Method: Compositional matrix adjust.
 Identities = 43/174 (24%), Positives = 77/174 (44%)
 Frame = +3

Query: 42  YDREALLGVQEDVDEYVKLGHEEQQRRLQSIIKKIDSDSDGFLTENELSQWIQMSFKHYA 101
           + R +LL + +   E++    +EQ    +      D D DG +T +EL   ++   ++  
Sbjct: 375 FVRHSLLIMSQ---EHIVTLTDEQVAEFKEAFSLFDKDGDGTITTSELGTVMRSLGQNPT 545

Query: 102 MQEAKQQFVEYDKNSDGAVTWDEYNIQMYDRVIDFDENTALDDTEEGSFRQLHLKDKKRF 161
             E +    E D + +G + ++E+   M  ++ D D    L +    +FR    KD   +
Sbjct: 546 ENELQDMINEVDADGNGTIDFEEFLHMMARKMKDTDCEEELRE----AFRVFD-KDGNGY 710

Query: 162 EKANQDSGPGLSLEEFIAFEHPEEVDYMTEFVIQEALEEHDKNGDGFVSLEEFL 215
             A +      +L E +     EEVD        E ++E D +GDG V+ EEF+
Sbjct: 711 ISAAELRHVMTNLGEKLT---DEEVD--------EMIKEADLDGDGMVNYEEFV 839
>32088
          Length = 1928

 Score = 31.6 bits (70), Expect = 0.39,   Method: Compositional matrix adjust.
 Identities = 17/63 (26%), Positives = 31/63 (49%)
 Frame = +1

Query: 63  EEQQRRLQSIIKKIDSDSDGFLTENELSQWIQMSFKHYAMQEAKQQFVEYDKNSDGAVTW 122
           E+Q   L+S+   ID D++G ++  EL    +    +    E +    +YD + DG +  
Sbjct: 931 EDQLTELRSVFDSIDDDNNGHISXGELDSAFRAVGLNIPGYELRTIMSKYDASGDGRLNM 1110

Query: 123 DEY 125
           DE+
Sbjct: 1111DEF 1119
>13551
          Length = 529

 Score = 31.2 bits (69), Expect = 0.54,   Method: Compositional matrix adjust.
 Identities = 30/119 (25%), Positives = 50/119 (42%), Gaps = 14/119 (11%)
 Frame = +1

Query: 188 YMTEFV----IQEALEEHDKNGDGFVSLEEFLGDY--RRDPTANEDPEWILVEKDRFVND 241
           +M E V    + + L E DKN DG +  EEF   Y  +R        E ++     F + 
Sbjct: 52  FMGEIVNEVKVTQWLREEDKNVDGCLDFEEFCALYKKKRQKEDKRKEELLMSVNQLFPSS 231

Query: 242 YDKDNDGRLDPQELLSWVVPNNQGIAQEEALHLID--------EMDLNSDKKLSEEEIL 292
              D+   LD    L   + N  G+  E  + L D        +++ N+D  +S+ E++
Sbjct: 232 QSGDDTISLDKMAGLLKQMNNMPGLCSEATMALTDTDIDSIIGKINRNNDNTISKSELV 408
>17484
          Length = 471

 Score = 30.8 bits (68), Expect = 0.67,   Method: Compositional matrix adjust.
 Identities = 14/53 (26%), Positives = 29/53 (54%)
 Frame = -3

Query: 41  DYDREALLGVQEDVDEYVKLGHEEQQRRLQSIIKKIDSDSDGFLTENELSQWI 93
           D + + ++ + E      K+G +     ++SII+ +D D DGF+   E +++I
Sbjct: 241 DQNGDGVISISELRQAMAKMGQKLSDADVESIIRDVDKDGDGFVNYEEFTKFI 83

 Score = 30.8 bits (68), Expect = 0.71,   Method: Compositional matrix adjust.
 Identities = 17/67 (25%), Positives = 32/67 (47%)
 Frame = -3

Query: 194 IQEALEEHDKNGDGFVSLEEFLGDYRRDPTANEDPEWILVEKDRFVNDYDKDNDGRLDPQ 253
           +++A    D+NGDG +S+ E      R   A    +    + +  + D DKD DG ++ +
Sbjct: 265 MRDAFRAFDQNGDGVISISEL-----RQAMAKMGQKLSDADVESIIRDVDKDGDGFVNYE 101

Query: 254 ELLSWVV 260
           E   ++ 
Sbjct: 100 EFTKFIA 80
>01773
          Length = 1950

 Score = 29.3 bits (64), Expect = 2.4,   Method: Compositional matrix adjust.
 Identities = 14/59 (23%), Positives = 28/59 (47%)
 Frame = +1

Query: 67  RRLQSIIKKIDSDSDGFLTENELSQWIQMSFKHYAMQEAKQQFVEYDKNSDGAVTWDEY 125
           ++L  + K  D   DG+L  +EL   +  S + +   +        DKN+D  + ++E+
Sbjct: 367 QKLAELFKAKDKSGDGYLDRDELKALLDESGQKFTADDVSAILKSADKNNDNKICFEEF 543
>15966
          Length = 362

 Score = 28.5 bits (62), Expect = 3.4,   Method: Compositional matrix adjust.
 Identities = 14/59 (23%), Positives = 28/59 (47%)
 Frame = +2

Query: 67  RRLQSIIKKIDSDSDGFLTENELSQWIQMSFKHYAMQEAKQQFVEYDKNSDGAVTWDEY 125
           ++L  + K  D   DG+L  +EL   +  S + +   +        DKN+D  + ++E+
Sbjct: 134 QKLAELFKAKDKSGDGYLDRDELKALLDESGQKFTADDVSAILKSADKNNDNKICFEEF 310
>14601
          Length = 472

 Score = 28.5 bits (62), Expect = 3.5,   Method: Compositional matrix adjust.
 Identities = 12/24 (50%), Positives = 16/24 (66%)
 Frame = +3

Query: 193 VIQEALEEHDKNGDGFVSLEEFLG 216
           V+ +  E  DK+ DGF+S EEF G
Sbjct: 141 VVSQIFEHEDKDKDGFISHEEFSG 212
>11270
          Length = 532

 Score = 28.5 bits (62), Expect = 3.7,   Method: Compositional matrix adjust.
 Identities = 28/78 (35%), Positives = 42/78 (53%), Gaps = 11/78 (14%)
 Frame = +2

Query: 117 DGAVTWDEYNIQMYD-RVIDFDE-----NTALD-DTEE--GSFRQLHL--KDKKRFEKAN 165
           DG VTWDEY  ++Y    +D DE     N A D +T+E   +   L L  +D+K F+ A+
Sbjct: 269 DGKVTWDEYLDKVYGFNKLDVDEMQKSVNEAKDKNTDEFKENVNNLELVDEDRKVFDAAD 448

Query: 166 QDSGPGLSLEEFIAFEHP 183
            +    L+ +E+ AF  P
Sbjct: 449 ANKDGSLNSKEYFAFFMP 502
>05237
          Length = 472

 Score = 27.7 bits (60), Expect = 5.8,   Method: Compositional matrix adjust.
 Identities = 18/68 (26%), Positives = 32/68 (47%)
 Frame = +3

Query: 194 IQEALEEHDKNGDGFVSLEEFLGDYRRDPTANEDPEWILVEKDRFVNDYDKDNDGRLDPQ 253
           ++EA    DK+G+GF+S  E      R    N   +    E D  + + D D DG+++ +
Sbjct: 33  LREAFRVFDKDGNGFISASEL-----RHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYE 197

Query: 254 ELLSWVVP 261
           E +  +  
Sbjct: 198 EFVKMMTT 221
>39823
          Length = 655

 Score = 27.3 bits (59), Expect = 8.7,   Method: Compositional matrix adjust.
 Identities = 33/120 (27%), Positives = 52/120 (43%), Gaps = 16/120 (13%)
 Frame = +3

Query: 107 QQFVEYDKNSDGAVTWDEYNIQMYDRVIDFDENTALDDTEEGSFRQLHLKDKK----RFE 162
           Q F E+DK+ D  VTW+EY         D    T+ D    G  R++    ++     F+
Sbjct: 69  QVFDEFDKDRDNQVTWEEYR--------DARSLTSKDPLARGQGRRMSEMTERVVRLEFQ 224

Query: 163 KANQDSGPGLSLEEF--IAFEH-------PEEVDYMTE---FVIQEALEEHDKNGDGFVS 210
            A+QD    L   EF  +A +H        E VD ++E     ++   +  D + DG V+
Sbjct: 225 MADQDEDQVLDWWEFLNLAAQHLLGRRSETELVDLLSEKEVVRLKVVFQGLDTDRDGVVT 404
>08108
          Length = 818

 Score = 26.9 bits (58), Expect = 9.9,   Method: Compositional matrix adjust.
 Identities = 15/55 (27%), Positives = 27/55 (49%)
 Frame = +2

Query: 72  IIKKIDSDSDGFLTENELSQWIQMSFKHYAMQEAKQQFVEYDKNSDGAVTWDEYN 126
           +IKK DSDS+G +  +E  + ++       + ++   F   D + DG +T  E  
Sbjct: 248 LIKKYDSDSNGDIDTDEFRKLVEGESDVARLAQSALMFKSLDADGDGQITASEIT 412
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|19527228|ref|NP_598768.1| CDGSH iron sulfur domain 1
[Mus musculus]
         (108 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

11077                                                                 110   2e-25
>11077
          Length = 921

 Score =  110 bits (274), Expect = 2e-25,   Method: Compositional matrix adjust.
 Identities = 45/66 (68%), Positives = 57/66 (86%)
 Frame = -1

Query: 43  AMVNLQIQKDNPKVVHAFDMEDLGDKAVYCRCWRSKKFPFCDGAHIKHNEETGDNVGPLI 102
            +VN+++QK++PKVV+  D+EDLGDK  YCRCWRSKKFP CDGAH KHNEET DNVGPL+
Sbjct: 630 VIVNMKVQKESPKVVNMVDIEDLGDKISYCRCWRSKKFPLCDGAHNKHNEETNDNVGPLV 451

Query: 103 IKKKET 108
           +++KE 
Sbjct: 450 LRRKEA 433
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|33468973|ref|NP_067453.1| tubby like protein 1 [Mus
musculus]
         (543 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

29211                                                                  67   2e-25
>29211
          Length = 396

 Score = 66.6 bits (161), Expect(3) = 2e-25,   Method: Compositional matrix adjust.
 Identities = 31/55 (56%), Positives = 40/55 (72%)
 Frame = +2

Query: 367 FIGKLRSNLLGNRFTVFDNGQNPQRGGGGDVGSLRQELAAVVYETNVLGFRGPRR 421
            + KLRSN+LG  FT+F+NG NP++    +    RQEL AV YETNVLGF+GPR+
Sbjct: 107 LLWKLRSNMLGTHFTLFNNGDNPKK----NAQDARQELVAVAYETNVLGFKGPRK 259

 Score = 44.3 bits (103), Expect(3) = 2e-25,   Method: Composition-based stats.
 Identities = 18/34 (52%), Positives = 26/34 (76%)
 Frame = +1

Query: 415 GFRGPRRMTVIIPGMNSDNERVPIRPRNASDGLL 448
           G +G ++MT+IIPGM SD++RV I P+   DGL+
Sbjct: 238 GLQGSKKMTIIIPGMTSDHKRVDITPKGNHDGLI 339

 Score = 43.1 bits (100), Expect(3) = 2e-25,   Method: Compositional matrix adjust.
 Identities = 20/31 (64%), Positives = 27/31 (87%)
 Frame = +3

Query: 339 AGRKRKRSKTANYLISSDPTNLSRGGENFIG 369
           +G+KRK S+T+NYL+S+DPT+LSR GE F G
Sbjct: 27  SGQKRK-SRTSNYLMSTDPTDLSRNGEAFCG 116
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|84579825|ref|NP_796307.2| exocyst complex component 3
[Mus musculus]
         (755 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

06935                                                                 113   2e-25
07992                                                                  57   3e-08
35576                                                                  31   1.8  
36840                                                                  29   7.2  
>06935
          Length = 1280

 Score =  113 bits (283), Expect = 2e-25,   Method: Compositional matrix adjust.
 Identities = 60/152 (39%), Positives = 95/152 (62%), Gaps = 1/152 (0%)
 Frame = +2

Query: 575 GSNAVDIICVTVEDYFNDFAKIKKPYKKRMTAEAHRRVVVEYLRAVMQKRISFRSAEERK 634
            SNAVD +C T  DY  DF  +K      +  E  RR++ EYLRA++ +++SF++ +ERK
Sbjct: 2   NSNAVDTVCATWADYAQDFVHMKPAMFDVLIHEGQRRILREYLRALLSRKLSFKNYDERK 181

Query: 635 EGAEKMVREAEQLRFLFRKLASGFGEDADG-HCDTIVAVAEVIKLTDPSLLYLEVSTLVS 693
             AEK+ +EA+Q++  FR++A     + DG   D + A+AEV++L D S+L LE++    
Sbjct: 182 ASAEKICKEAKQMKDQFREMAP----NQDGAQFDVLPALAEVLRLRDTSMLALEITGFAQ 349

Query: 694 KYPDIRDDHIGALLALRGDASRDMKQTIMETL 725
           KYPDIR D + +L+  RG  +  M  + ++TL
Sbjct: 350 KYPDIRMDQLISLILCRGIPAALMPNSWLKTL 445
>07992
          Length = 470

 Score = 56.6 bits (135), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 33/79 (41%), Positives = 47/79 (59%), Gaps = 1/79 (1%)
 Frame = +2

Query: 667 DTIVAVAEVIKLTDPSLLYLEVSTLVSKYPDIRDDHIGALLALRGDASR-DMKQTIMETL 725
           D + A+AEV++L D S+L LE++    KYPDIR D + +L+  RGD SR D KQ   +TL
Sbjct: 20  DVLPALAEVLRLRDTSMLALEITGFAQKYPDIRMDQLISLILCRGDTSRSDAKQLAQDTL 199

Query: 726 EQGPMQASPNYVPIFKEIV 744
               ++  P    IF +I 
Sbjct: 200 GDEELRHKPE--GIFSDIA 250
>35576
          Length = 339

 Score = 30.8 bits (68), Expect = 1.8,   Method: Compositional matrix adjust.
 Identities = 14/37 (37%), Positives = 22/37 (59%)
 Frame = -1

Query: 374 VSALEPLLSPNIVSELLDTYMSTLTSNIIAWLRKALE 410
            SAL P+L+P +  + + T   TLTS++I+ L   L 
Sbjct: 114 TSALTPMLTPTLTPKHIPTLTPTLTSSLISPLTSTLN 4
>36840
          Length = 559

 Score = 28.9 bits (63), Expect = 7.2,   Method: Compositional matrix adjust.
 Identities = 16/60 (26%), Positives = 29/60 (48%)
 Frame = -2

Query: 357 YTSAEMMGNVELAPEVDVSALEPLLSPNIVSELLDTYMSTLTSNIIAWLRKALETDKKDW 416
           +T  E  G+V+L   + +  L+P     +V+  L  YM+TL    +  +   + TD + W
Sbjct: 438 FTEEEETGDVQLQDHIRLQELDPEGKTCLVANSLKAYMTTLPEPELKRVASKINTDCQLW 259
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|110227381|ref|NP_033925.2| calpain, small subunit 1
[Mus musculus]
         (268 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

16109                                                                 111   3e-25
03732                                                                  91   4e-19
18677                                                                  89   2e-18
12214                                                                  80   1e-15
27864                                                                  53   1e-07
08108                                                                  52   2e-07
32241                                                                  39   0.003
07678                                                                  34   0.059
16554                                                                  33   0.086
14594                                                                  33   0.089
25291                                                                  32   0.33 
10283                                                                  31   0.53 
26849                                                                  30   1.3  
>16109
          Length = 1490

 Score =  111 bits (278), Expect = 3e-25,   Method: Compositional matrix adjust.
 Identities = 59/188 (31%), Positives = 93/188 (49%)
 Frame = +3

Query: 80  PPPPRSHYSNIEANESEEVRQFRKLFVQLAGDDMEVSATELMNILNKVVTRHPDLKTDGF 139
           P P        E  E E V    +LF +  G   +V A  L  IL++   R    K DG+
Sbjct: 759 PEPTEEPIGPTEEIEPEPVGLIERLFHKHQGPSSKVDAARLQRILDEA-KREEYNKEDGY 935

Query: 140 GIDTCRSMVAVMDSDTTGKLGFEEFKYLWNNIKKWQAIYKRFDTDRSGTIGSHELPGAFE 199
            ++TCR +++++D D TG+L  E  K +WN +K W   +   D  +   + + EL   F+
Sbjct: 936 SLETCRCLLSLLDRDITGRLSLEAVKTIWNYVKVWTKAFHTTDVSKDKLVDTFELKDLFK 1115

Query: 200 AAGFHLNEHLYSMIIRRYADESGNMDFDNFISCLVRLDAMFRAFKSLDKNGTGQIQVNIQ 259
             GF ++  +   I+ RY DE G +  D+F+    R+ A++  FK   K+  G I  N+ 
Sbjct: 1116KIGFTIDSEVLKRIVCRYGDEDGKIHEDDFLQSFCRVLALYHIFKK--KSSDGLITQNLS 1289

Query: 260 EWLQLTMY 267
           EWL  T+Y
Sbjct: 1290EWLSSTLY 1313
>03732
          Length = 1114

 Score = 91.3 bits (225), Expect = 4e-19,   Method: Compositional matrix adjust.
 Identities = 39/129 (30%), Positives = 76/129 (58%), Gaps = 1/129 (0%)
 Frame = -1

Query: 139  FGIDTCRSMVAVMDSDTTGKLGFEEFKYLWNNIKKWQAIYKRFDTDRSGTIGSHELPGAF 198
            F  +T R M+ + D D +G + F+EF+ LW  +  WQ  ++ +D D SG+I  +EL  A 
Sbjct: 1000 FNPETVRLMIGMFDRDNSGTINFQEFQALWKYVTDWQNCFRSYDRDNSGSIDRNELKNAL 821

Query: 199  EAAGFHLNEHLYSMIIRRYADES-GNMDFDNFISCLVRLDAMFRAFKSLDKNGTGQIQVN 257
               G+ L++  + ++++++  +  G + FD+FI C V L  +  +F++ D++  G IQ++
Sbjct: 820  TGFGYRLSDRFFDVLVKKFDRQGKGTVAFDDFIQCCVVLQTLTTSFRTHDQDQDGWIQIS 641

Query: 258  IQEWLQLTM 266
             +++L L  
Sbjct: 640  YEQFLTLVF 614
>18677
          Length = 754

 Score = 89.4 bits (220), Expect = 2e-18,   Method: Compositional matrix adjust.
 Identities = 44/151 (29%), Positives = 80/151 (52%), Gaps = 1/151 (0%)
 Frame = +2

Query: 104 LFVQLAGDDMEVSATELMNILNKVVTRHPDLKTD-GFGIDTCRSMVAVMDSDTTGKLGFE 162
           +F +  G D  +   EL   L  V     D+K    F I+ CRS++ +MD + +G+L F 
Sbjct: 305 IFHKHCGSDSRLDPGELQKFLEDVSDE--DVKQRLKFNIEQCRSLLPMMDENRSGRLEFP 478

Query: 163 EFKYLWNNIKKWQAIYKRFDTDRSGTIGSHELPGAFEAAGFHLNEHLYSMIIRRYADESG 222
           E K LW  IK ++ ++ +FD +RSG + ++EL   F   GF +   + + I+RRY D   
Sbjct: 479 EAKRLWKEIKAYREVFLQFDKNRSGLVDTYELGNMFSKLGFPVTRPVLTSIVRRYGDRRN 658

Query: 223 NMDFDNFISCLVRLDAMFRAFKSLDKNGTGQ 253
            +  ++F+  ++RL  ++  +   + N + +
Sbjct: 659 QISLEDFVVVILRLIQLYNIYVKQEGNSSKR 751
>12214
          Length = 654

 Score = 79.7 bits (195), Expect = 1e-15,   Method: Compositional matrix adjust.
 Identities = 37/126 (29%), Positives = 74/126 (58%), Gaps = 2/126 (1%)
 Frame = -3

Query: 143 TCRSMVAVMDSDTTGKLGFEEFKYLWNNIKKWQAIYKRFDTDRSGTIGSHELPGAFEAAG 202
           T R M+ + D D +G +   EF+ LW  I++W++ ++R+D++RSG+I  +EL  A++  G
Sbjct: 652 TSRLMIGMFDRDMSGTIDINEFQSLWQYIQQWRSTFERYDSNRSGSIEGNELQAAYQQMG 473

Query: 203 FHLNEHLYSMIIRRYADESG--NMDFDNFISCLVRLDAMFRAFKSLDKNGTGQIQVNIQE 260
           F+++      ++ ++ D  G  ++  DNFI   V L ++  AF+  D   TG + +  ++
Sbjct: 472 FNVSPRFVQTVLYKF-DHFGRRSLTLDNFIQSCVMLKSLTDAFRQRDTGSTGVVNMAYED 296

Query: 261 WLQLTM 266
           +L + +
Sbjct: 295 FLTMAV 278
>27864
          Length = 343

 Score = 53.1 bits (126), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 21/56 (37%), Positives = 34/56 (60%)
 Frame = +1

Query: 139 FGIDTCRSMVAVMDSDTTGKLGFEEFKYLWNNIKKWQAIYKRFDTDRSGTIGSHEL 194
           F  +T R M+ + D D +G + F+EF+ LW  +  WQ  ++ +D D SG+I  +EL
Sbjct: 115 FNPETVRLMIGMFDRDNSGTINFQEFQALWKYVTDWQNCFRSYDRDNSGSIDRNEL 282
>08108
          Length = 818

 Score = 52.0 bits (123), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 32/92 (34%), Positives = 49/92 (53%), Gaps = 7/92 (7%)
 Frame = +2

Query: 173 KWQAIYKRFDTDRSGTIGSHELPGAFEAAGFHLNEHLYSMIIRRY-ADESGNMDFDNFI- 230
           + Q  +  FDTD SG+I + EL  A  A G  + +   + +I++Y +D +G++D D F  
Sbjct: 128 ECQTAFAVFDTDGSGSISAGELGEALRAQGADITDDQTAELIKKYDSDSNGDIDTDEFRK 307

Query: 231 -----SCLVRLDAMFRAFKSLDKNGTGQIQVN 257
                S + RL      FKSLD +G GQI  +
Sbjct: 308 LVEGESDVARLAQSALMFKSLDADGDGQITAS 403

 Score = 28.5 bits (62), Expect = 2.8,   Method: Compositional matrix adjust.
 Identities = 20/100 (20%), Positives = 40/100 (40%), Gaps = 6/100 (6%)
 Frame = +2

Query: 142 DTCRSMVAVMDSDTTGKLGFEEFKYLWNN------IKKWQAIYKRFDTDRSGTIGSHELP 195
           D    ++   DSD+ G +  +EF+ L         + +   ++K  D D  G I + E+ 
Sbjct: 233 DQTAELIKKYDSDSNGDIDTDEFRKLVEGESDVARLAQSALMFKSLDADGDGQITASEIT 412

Query: 196 GAFEAAGFHLNEHLYSMIIRRYADESGNMDFDNFISCLVR 235
            A         +  ++ ++   A   G + F  F+ C  +
Sbjct: 413 EAQGKKTIGATDGQFAAMVEAAA--GGVLTFAAFLKCFAK 526
>32241
          Length = 328

 Score = 38.5 bits (88), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 20/71 (28%), Positives = 39/71 (54%), Gaps = 1/71 (1%)
 Frame = -2

Query: 175 QAIYKRFDTDRSGTIGSHELPGAFEAAGFHLNEHLYSMIIRRYAD-ESGNMDFDNFISCL 233
           +  ++R DT+RSG+I ++EL  A+   GF+++      ++ ++      ++  D FI   
Sbjct: 243 EGTFERIDTNRSGSIEANELVTAYRQMGFNVSPQFVQTVLYKFDHLARRSLSLDMFIQSC 64

Query: 234 VRLDAMFRAFK 244
           V L ++  AFK
Sbjct: 63  VMLRSLTDAFK 31
>07678
          Length = 958

 Score = 34.3 bits (77), Expect = 0.059,   Method: Compositional matrix adjust.
 Identities = 19/44 (43%), Positives = 25/44 (56%), Gaps = 6/44 (13%)
 Frame = +1

Query: 219 DESGNMDFDNFISCL------VRLDAMFRAFKSLDKNGTGQIQV 256
           DZSG +DFD F+  L      +R D + RAF+ LDK G G + V
Sbjct: 466 DZSGTIDFDEFLVKLRPPMSQMRKDLIQRAFQKLDKTGDGVVTV 597
>16554
          Length = 970

 Score = 33.5 bits (75), Expect = 0.086,   Method: Compositional matrix adjust.
 Identities = 17/57 (29%), Positives = 28/57 (49%)
 Frame = -2

Query: 198 FEAAGFHLNEHLYSMIIRRYADESGNMDFDNFISCLVRLDAMFRAFKSLDKNGTGQI 254
           F  A  HLN   + + I+ YA +     ++ F +CL R+  MF+    L K+   Q+
Sbjct: 243 FSTAS*HLNVBCFLLSIKXYAHQXSTTSYNYFHACL-RMPEMFKCLARLLKHDVVQL 76
>14594
          Length = 1014

 Score = 33.5 bits (75), Expect = 0.089,   Method: Compositional matrix adjust.
 Identities = 33/148 (22%), Positives = 68/148 (45%), Gaps = 9/148 (6%)
 Frame = +3

Query: 96  EEVRQFRKLFVQLAGD-DMEVSATELMNILNKVVTRHPDLKTDGFGIDTCRSMVAVMDSD 154
           E+V +F++ F     D D  ++ +EL  ++ + + ++P         +  + M+  +D+D
Sbjct: 432 EQVAEFKEAFSLFDKDGDGTITTSELGTVM-RSLGQNPTE-------NELQDMINEVDAD 587

Query: 155 TTGKLGFEEFKYLWNNIKK-------WQAIYKRFDTDRSGTIGSHELPGAFEAAGFHL-N 206
             G + FEEF ++     K        +  ++ FD D +G I + EL       G  L +
Sbjct: 588 GNGTIDFEEFLHMMARKMKDTDCEEELREAFRVFDKDGNGYISAAELRHVMTNLGEKLTD 767

Query: 207 EHLYSMIIRRYADESGNMDFDNFISCLV 234
           E +  MI     D  G ++++ F++ + 
Sbjct: 768 EEVDEMIKEADLDGDGMVNYEEFVTMMT 851
>25291
          Length = 1059

 Score = 31.6 bits (70), Expect = 0.33,   Method: Compositional matrix adjust.
 Identities = 17/61 (27%), Positives = 27/61 (44%)
 Frame = +2

Query: 198 FEAAGFHLNEHLYSMIIRRYADESGNMDFDNFISCLVRLDAMFRAFKSLDKNGTGQIQVN 257
           F  A  HLN   + + I+ YA +     ++ F +CL R+  MF+    L K        N
Sbjct: 596 FSTAS*HLNVBCFLLSIKPYAHQXSTTSYNYFHACL-RMLEMFKYLARLPKXACRLCLAN 772

Query: 258 I 258
           +
Sbjct: 773 L 775
>10283
          Length = 421

 Score = 30.8 bits (68), Expect = 0.53,   Method: Compositional matrix adjust.
 Identities = 16/52 (30%), Positives = 28/52 (53%)
 Frame = -3

Query: 198 FEAAGFHLNEHLYSMIIRRYADESGNMDFDNFISCLVRLDAMFRAFKSLDKN 249
           F  A  HLN + + + I+ YA ++    ++ F +CL R+  MF+    L K+
Sbjct: 365 FSTAS*HLNVNCFLLSIKPYAHQTSTTSYNYFHACL-RMLEMFKYLARLPKH 213
>26849
          Length = 649

 Score = 29.6 bits (65), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 12/22 (54%), Positives = 15/22 (68%)
 Frame = +3

Query: 235 RLDAMFRAFKSLDKNGTGQIQV 256
           RL+ + RAF  LD NG GQI +
Sbjct: 378 RLNVIHRAFDKLDANGDGQITI 443

 Score = 27.7 bits (60), Expect = 4.4,   Method: Compositional matrix adjust.
 Identities = 18/50 (36%), Positives = 25/50 (50%), Gaps = 6/50 (12%)
 Frame = +2

Query: 150 VMDSDTTGKLGFEEFK------YLWNNIKKWQAIYKRFDTDRSGTIGSHE 193
           VMD D +  L  EEFK      ++  N    + ++ RFD D +GTI   E
Sbjct: 191 VMDKDGSKVLSLEEFKKGILDMHIDINEADIEDMFYRFDNDGNGTINMTE 340
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|66773171|ref|NP_808346.3| actin-binding LIM protein 2
[Mus musculus]
         (612 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

11928                                                                 112   4e-25
09680                                                                  79   6e-15
07437                                                                  75   7e-14
14307                                                                  69   4e-12
05726                                                                  55   9e-08
34420                                                                  43   3e-04
05103                                                                  41   0.002
26762                                                                  39   0.007
30169                                                                  39   0.008
04349                                                                  37   0.018
35341                                                                  34   0.13 
29549                                                                  31   1.7  
24891                                                                  30   3.9  
01348                                                                  28   8.4  
>11928
          Length = 1623

 Score =  112 bits (280), Expect = 4e-25,   Method: Compositional matrix adjust.
 Identities = 75/233 (32%), Positives = 103/233 (44%), Gaps = 1/233 (0%)
 Frame = -2

Query: 23   LCNTCGNVCKGEVLRVQNKYFHIRCFVCKACGCDLAEGGFFVRQGEHICTRDYQRLYGTR 82
            +C  C     G+V+    + +H+  FVC  C   L    F+ R     C  DY  L+  R
Sbjct: 1601 VCAACNKPIVGQVIAALGRTWHVEHFVCAHCEQPLGTSNFYERDSVAYCEVDYHNLFAPR 1422

Query: 83   CFSCDRFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSPPTLLGN 142
            C  C+  I  + ++AL K +HP+ F CA C   F   D    NGK               
Sbjct: 1421 CAYCNGPIVDKCITALEKMWHPEHFFCAQCGRQFGDEDFHEKNGKA-----------YCR 1275

Query: 143  SAHVAQGLRSCGGCGLEIKNGQALVALDKHWHLGCFKCKTC-GKLLNAEYISKDGLPYCE 201
              +       CGGCG+ I     + AL++ WH  CF C  C        +   DGLPYCE
Sbjct: 1274 DDYFQMFAPKCGGCGMPIMENY-ISALNRQWHPQCFCCWECQAPFGTGSFYDHDGLPYCE 1098

Query: 202  ADYHSKFGIRCDGCEKYITGRVLEAGEKHYHPSCALCVRCGQMFSEGEEMYLQ 254
              YH+K G  C  C+K ITGR + A  K +HP    C+R   +    E+ +LQ
Sbjct: 1097 THYHAKKGSLCASCQKPITGRCITAMFKKFHPE-HFCLR--LLHQTAEQGHLQ 948
>09680
          Length = 878

 Score = 79.0 bits (193), Expect = 6e-15,   Method: Compositional matrix adjust.
 Identities = 55/184 (29%), Positives = 81/184 (44%), Gaps = 2/184 (1%)
 Frame = -2

Query: 82  RCFSCDRFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSPPTLLG 141
           +C  C+  I   VV ALGK YHP+ F+C  C       D       E +C          
Sbjct: 718 QCHKCNEAITSRVVFALGKNYHPEHFLCRDCDKQIK-DDIFNIQQGEPVC---------- 572

Query: 142 NSAHVAQGLRSCGGCGLEIKNGQALVALDKHWHLGCFKCKTCGK--LLNAEYISKDGLPY 199
           N+ ++ +   +C GC   I +G  + A+  +WH  CF C    K  L ++ +  ++G  Y
Sbjct: 571 NACYLERYTSTCAGCKEPI-HGTTISAMGNNWHEHCFVCDGACKQPLKDSSFFEREGKAY 395

Query: 200 CEADYHSKFGIRCDGCEKYITGRVLEAGEKHYHPSCALCVRCGQMFSEGEEMYLQGSSIW 259
           C  DY   F +RC  CEK IT   + A    +H  C  C RC     + +   ++G    
Sbjct: 394 CRQDYEDLFAVRCAKCEKPITENAIVAMNAKWHSDCFCCNRCDNPI-KTKTFTIEGDKPI 218

Query: 260 HPAC 263
            PAC
Sbjct: 217 CPAC 206

 Score = 65.1 bits (157), Expect = 8e-11,   Method: Compositional matrix adjust.
 Identities = 49/186 (26%), Positives = 72/186 (38%), Gaps = 7/186 (3%)
 Frame = -2

Query: 24  CNTCGNVCKGEVLRVQNKYFHIRCFVCKACGCDLAEGGFFVRQGEHICTRDYQRLYGTRC 83
           C+ C       V+    K +H   F+C+ C   + +  F ++QGE +C   Y   Y + C
Sbjct: 715 CHKCNEAITSRVVFALGKNYHPEHFLCRDCDKQIKDDIFNIQQGEPVCNACYLERYTSTC 536

Query: 84  FSCDRFIEGEVVSALGKTYHPDCFVC-AVCRLPFPPGDRVTFNGKECMCQKCSPPTLLGN 142
             C   I G  +SA+G  +H  CFVC   C+ P          GK               
Sbjct: 535 AGCKEPIHGTTISAMGNNWHEHCFVCDGACKQPLKDSSFFEREGK--------------- 401

Query: 143 SAHVAQGLRS-----CGGCGLEIKNGQALVALDKHWHLGCFKCKTCGKLLNAEYISKDG- 196
            A+  Q         C  C   I    A+VA++  WH  CF C  C   +  +  + +G 
Sbjct: 400 -AYCRQDYEDLFAVRCAKCEKPITEN-AIVAMNAKWHSDCFCCNRCDNPIKTKTFTIEGD 227

Query: 197 LPYCEA 202
            P C A
Sbjct: 226 KPICPA 209
>07437
          Length = 951

 Score = 75.5 bits (184), Expect = 7e-14,   Method: Compositional matrix adjust.
 Identities = 66/215 (30%), Positives = 91/215 (42%), Gaps = 10/215 (4%)
 Frame = +3

Query: 36  LRVQNKYFHIRCFVCKACGCDLAEGGFFVRQGEHIC--TRDYQRLYGT---RCFSCDRFI 90
           ++  N  +H +CF+C+ CG  +A+ GF    G  +C      ++  GT    C  C   I
Sbjct: 3   IKAMNSAWHPQCFLCQLCGTCMADSGFVKNAGRALCRECNAKEKARGTGKYVCHKCHDVI 182

Query: 91  EGE-VVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSPPTLLGNSAHVAQG 149
           E    +   G+ YHP  F C  C +      R      E  C +C          H   G
Sbjct: 183 EMNGHIKFRGEAYHPYHFNCHSCGVELNTEARE--KDSELYCLRC----------HDKMG 326

Query: 150 LRSCGGCGLEIKNGQALVALDKHWHLGCFKCKTCGK-LLNAEYISKDGLPYCEADYHSKF 208
           +  CG C   I+  + + AL K WH+  F C  C K  L   +  K GL YCE  YH  F
Sbjct: 327 IPICGACRRPIEE-RVVHALGKAWHVEHFVCAKCEKPFLGTRHYEKKGLAYCEIHYHQLF 503

Query: 209 GIRCDGCEKYITGRVLEAGEKHY---HPSCALCVR 240
           G  C  C   I G V  A  K +   H +C++C R
Sbjct: 504 GNICFVCNNIINGDVFSAFNKAWCVHHFACSICDR 608

 Score = 48.5 bits (114), Expect = 8e-06,   Method: Compositional matrix adjust.
 Identities = 48/171 (28%), Positives = 71/171 (41%), Gaps = 2/171 (1%)
 Frame = +3

Query: 36  LRVQNKYFHIRCFVCKACGCDLAEGGFFVRQGEHICTRDYQRLYGTRCFSCDRFIEGEVV 95
           ++ + + +H   F C +CG +L       +  E  C R + ++    C +C R IE  VV
Sbjct: 198 IKFRGEAYHPYHFNCHSCGVELNTEAR-EKDSELYCLRCHDKMGIPICGACRRPIEERVV 374

Query: 96  SALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSPPTLLGNSAHVAQGLRSCGG 155
            ALGK +H + FVCA C  PF  G R         C+      L GN   V         
Sbjct: 375 HALGKAWHVEHFVCAKCEKPF-LGTRHYEKKGLAYCEI-HYHQLFGNICFVCNN------ 530

Query: 156 CGLEIKNGQALVALDKHWHLGCFKCKTCGKLLN--AEYISKDGLPYCEADY 204
               I NG    A +K W +  F C  C + ++   ++   D  P C+  Y
Sbjct: 531 ----IINGDVFSAFNKAWCVHHFACSICDRKMSQKTKFFEFDQKPVCKNCY 671

 Score = 47.8 bits (112), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 26/90 (28%), Positives = 41/90 (45%)
 Frame = +3

Query: 23  LCNTCGNVCKGEVLRVQNKYFHIRCFVCKACGCDLAEGGFFVRQGEHICTRDYQRLYGTR 82
           +C  C    +  V+    K +H+  FVC  C         + ++G   C   Y +L+G  
Sbjct: 333 ICGACRRPIEERVVHALGKAWHVEHFVCAKCEKPFLGTRHYEKKGLAYCEIHYHQLFGNI 512

Query: 83  CFSCDRFIEGEVVSALGKTYHPDCFVCAVC 112
           CF C+  I G+V SA  K +    F C++C
Sbjct: 513 CFVCNNIINGDVFSAFNKAWCVHHFACSIC 602
>14307
          Length = 816

 Score = 69.3 bits (168), Expect = 4e-12,   Method: Compositional matrix adjust.
 Identities = 68/237 (28%), Positives = 91/237 (38%), Gaps = 16/237 (6%)
 Frame = +2

Query: 15  EKPASTAILCNTCGNVCKGEVLRVQ----------NKYFHIRCFVCKACGCDLAEGGFFV 64
           E P+ T   C      CKGE+ +++             +H  CFVC  C  +L     + 
Sbjct: 158 EAPSDTTCHC------CKGEIDKLELVVTAPKVGEGTVWHPACFVCSTCE-ELLVDLVYC 316

Query: 65  RQGEHI-CTRDYQRLYGTRCFSCDRFI-EGEVVSALGKTYHPDCFVCAVCRLPFPPGDRV 122
           +  +H+ C R Y  L   RC  CD  I  GE   A+ + YH D   C  C        R 
Sbjct: 317 QHDKHLYCQRHYAELIRPRCPGCDELIFSGEYTKAMEECYHKDHLACWQCDKQLVSC-RY 493

Query: 123 TFNGKECMCQKCSPPTLLGNSAHVAQGLRSCGGCGLEI-KNGQALVALDKHWHLGCFKCK 181
                   C  C    L  N          C  C   I  + + L   DKHWH  CFKC 
Sbjct: 494 IMRDDHPHCVPCYQ-ALFANK---------CEDCDKPIGPDYKDLSYKDKHWHEFCFKCT 643

Query: 182 TCGK-LLNAEYISKDGLPYCEADYHSKFGIRCDGCEKYITG--RVLEAGEKHYHPSC 235
            C K L++  +  K+   +C   Y + F  RCDGC     G  +  E   K +H  C
Sbjct: 644 MCDKSLVDQPFAPKNEKIFCSECYDNSFAARCDGCGNPFKGGMKKFEYKGKQWHDEC 814
>05726
          Length = 733

 Score = 55.1 bits (131), Expect = 9e-08,   Method: Compositional matrix adjust.
 Identities = 34/110 (30%), Positives = 49/110 (44%), Gaps = 5/110 (4%)
 Frame = +1

Query: 159 EIKNGQALVALDKHWHLGCFKCKTCGKLLNAE-YISKDGLPYCEADYHSKFGIRCDGCEK 217
           ++ N   +   +  WH  CF C  C K+L  E + SKD  PYC   +   F  +C  C+K
Sbjct: 88  QVINKGGISYKNTPWHRECFTCTHCDKMLAGEKFTSKDDQPYCGDCFGDLFAKKCCRCQK 267

Query: 218 YITG----RVLEAGEKHYHPSCALCVRCGQMFSEGEEMYLQGSSIWHPAC 263
            ITG    + +   E+H+H  C  C +C Q    G    +    I  P C
Sbjct: 268 AITGIGGTKFISFEERHWHSDCFTCFKC-QASMVGRGFLMNDDDIVCPDC 414

 Score = 42.7 bits (99), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 34/138 (24%), Positives = 50/138 (36%), Gaps = 7/138 (5%)
 Frame = +1

Query: 62  FFVRQGEHICTRDYQRLYGTRCFSCDRFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDR 121
           F  R    IC   Y+  Y  RCF C + I    +S     +H +CF C  C      G++
Sbjct: 10  FIPRDDRVICVPCYENNYAQRCFKCSQVINKGGISYKNTPWHRECFTCTHCD-KMLAGEK 186

Query: 122 VTFNGKECMCQKCSPPTLLGNSAHVAQGLRSCGGCGLEIKNGQALVALDKHWHLGCFKCK 181
            T    +  C  C             + +   GG        + +   ++HWH  CF C 
Sbjct: 187 FTSKDDQPYCGDCFGDLFAKKCCRCQKAITGIGG-------TKFISFEERHWHSDCFTCF 345

Query: 182 TC-------GKLLNAEYI 192
            C       G L+N + I
Sbjct: 346 KCQASMVGRGFLMNDDDI 399

 Score = 35.8 bits (81), Expect = 0.052,   Method: Compositional matrix adjust.
 Identities = 25/94 (26%), Positives = 39/94 (41%), Gaps = 4/94 (4%)
 Frame = +1

Query: 24  CNTCGNVCKGEVLRVQNKYFHIRCFVCKACGCDLAEGGFFVRQGEHICTRDYQRLYGTRC 83
           C  C  V     +  +N  +H  CF C  C   LA   F  +  +  C   +  L+  +C
Sbjct: 73  CFKCSQVINKGGISYKNTPWHRECFTCTHCDKMLAGEKFTSKDDQPYCGDCFGDLFAKKC 252

Query: 84  FSCDRFIEG----EVVSALGKTYHPDCFVCAVCR 113
             C + I G    + +S   + +H DCF C  C+
Sbjct: 253 CRCQKAITGIGGTKFISFEERHWHSDCFTCFKCQ 354
>34420
          Length = 719

 Score = 43.1 bits (100), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 26/78 (33%), Positives = 36/78 (46%), Gaps = 4/78 (5%)
 Frame = +2

Query: 190 EYISKDGLPYCEADYHSKFGIRCDGCEKYITG----RVLEAGEKHYHPSCALCVRCGQMF 245
           ++ SKD  PYC   +   F  RC  C + ITG    + +   E+H+H  C +C RC    
Sbjct: 5   KFTSKDEQPYCGDCFGELFAKRCIRCTQPITGIGGTKFISFEERHWHSDCFVCYRCNASM 184

Query: 246 SEGEEMYLQGSSIWHPAC 263
             G    +QG  I  P C
Sbjct: 185 V-GRGFLMQGEEILCPDC 235

 Score = 30.0 bits (66), Expect = 3.1,   Method: Compositional matrix adjust.
 Identities = 20/68 (29%), Positives = 29/68 (42%), Gaps = 4/68 (5%)
 Frame = +2

Query: 71  CTRDYQRLYGTRCFSCDRFIEG----EVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNG 126
           C   +  L+  RC  C + I G    + +S   + +H DCFVC  C      G      G
Sbjct: 35  CGDCFGELFAKRCIRCTQPITGIGGTKFISFEERHWHSDCFVCYRCNASM-VGRGFLMQG 211

Query: 127 KECMCQKC 134
           +E +C  C
Sbjct: 212 EEILCPDC 235
>05103
          Length = 1504

 Score = 40.8 bits (94), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 19/68 (27%), Positives = 35/68 (51%), Gaps = 6/68 (8%)
 Frame = +2

Query: 3   AVSQPQAAHAPLEKPAST------AILCNTCGNVCKGEVLRVQNKYFHIRCFVCKACGCD 56
           +VS  ++  AP+ KP         ++ C  C  +  G +++     +H+ CF C++C  +
Sbjct: 563 SVSGFRSVTAPVGKPPGEQKQQQPSMRCGGCDMLATGVIVKANGVPYHVACFKCESCSMN 742

Query: 57  LAEGGFFV 64
           L + GFFV
Sbjct: 743 LKQKGFFV 766

 Score = 34.3 bits (77), Expect = 0.14,   Method: Compositional matrix adjust.
 Identities = 15/39 (38%), Positives = 18/39 (46%)
 Frame = +2

Query: 76  QRLYGTRCFSCDRFIEGEVVSALGKTYHPDCFVCAVCRL 114
           Q+    RC  CD    G +V A G  YH  CF C  C +
Sbjct: 623 QQQPSMRCGGCDMLATGVIVKANGVPYHVACFKCESCSM 739

 Score = 33.9 bits (76), Expect = 0.20,   Method: Compositional matrix adjust.
 Identities = 19/57 (33%), Positives = 29/57 (50%), Gaps = 2/57 (3%)
 Frame = +2

Query: 153 CGGCGLEIKNGQALVALDKHWHLGCFKCKTCGKLLNAE--YISKDGLPYCEADYHSK 207
           CGGC + +  G  + A    +H+ CFKC++C   L  +  ++  D L YCE     K
Sbjct: 644 CGGCDM-LATGVIVKANGVPYHVACFKCESCSMNLKQKGFFVVDDKL-YCETHARQK 808

 Score = 30.8 bits (68), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 12/32 (37%), Positives = 18/32 (56%)
 Frame = +2

Query: 210 IRCDGCEKYITGRVLEAGEKHYHPSCALCVRC 241
           +RC GC+   TG +++A    YH +C  C  C
Sbjct: 638 MRCGGCDMLATGVIVKANGVPYHVACFKCESC 733
>26762
          Length = 399

 Score = 38.5 bits (88), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 25/79 (31%), Positives = 32/79 (40%), Gaps = 4/79 (5%)
 Frame = +1

Query: 191 YISKDGLPYCEADYHSKFGIRCDGCEKYITG----RVLEAGEKHYHPSCALCVRCGQMFS 246
           + S+D  PYC       F  RC  C K ITG    R +   E+H+H  C +C  C     
Sbjct: 7   FTSRDEKPYCAECLGELFAKRCTSCVKPITGIGGTRFISFEERHWHHDCFVCASCKASLV 186

Query: 247 EGEEMYLQGSSIWHPACRQ 265
            G      G  I  P C +
Sbjct: 187 -GRGFITDGPDILCPDCAK 240

 Score = 34.3 bits (77), Expect = 0.14,   Method: Compositional matrix adjust.
 Identities = 24/83 (28%), Positives = 37/83 (44%), Gaps = 4/83 (4%)
 Frame = +1

Query: 62  FFVRQGEHICTRDYQRLYGTRCFSCDRFIEG----EVVSALGKTYHPDCFVCAVCRLPFP 117
           F  R  +  C      L+  RC SC + I G      +S   + +H DCFVCA C+    
Sbjct: 7   FTSRDEKPYCAECLGELFAKRCTSCVKPITGIGGTRFISFEERHWHHDCFVCASCKASLV 186

Query: 118 PGDRVTFNGKECMCQKCSPPTLL 140
               +T +G + +C  C+   L+
Sbjct: 187 GRGFIT-DGPDILCPDCAKQKLM 252
>30169
          Length = 426

 Score = 38.5 bits (88), Expect = 0.008,   Method: Composition-based stats.
 Identities = 19/59 (32%), Positives = 33/59 (55%), Gaps = 2/59 (3%)
 Frame = -1

Query: 153 CGGCGLEIKNGQALVALDKHWHLGCFKCKTCGKLLNAEYIS--KDGLPYCEADYHSKFG 209
           C  CG  +   + +  + K +H  CFKC +C K+L++  ++  +D + YC+A Y   FG
Sbjct: 405 CAVCGKAVYFAERVAGMGKVYHKACFKCTSCRKILDSTLLTQHQDNI-YCKACYGKNFG 232

 Score = 29.3 bits (64), Expect = 4.9,   Method: Composition-based stats.
 Identities = 13/32 (40%), Positives = 17/32 (53%), Gaps = 1/32 (3%)
 Frame = -1

Query: 83  CFSCDRFIE-GEVVSALGKTYHPDCFVCAVCR 113
           C  C + +   E V+ +GK YH  CF C  CR
Sbjct: 405 CAVCGKAVYFAERVAGMGKVYHKACFKCTSCR 310
>04349
          Length = 1161

 Score = 37.4 bits (85), Expect = 0.018,   Method: Compositional matrix adjust.
 Identities = 19/71 (26%), Positives = 30/71 (42%), Gaps = 4/71 (5%)
 Frame = +3

Query: 16  KPASTAILCNTCG----NVCKGEVLRVQNKYFHIRCFVCKACGCDLAEGGFFVRQGEHIC 71
           K    A+    CG     V   E + ++   +H  CF C  C C L    F + +    C
Sbjct: 198 KSMRVAVQLEKCGACHKTVYAMEKIEIEKNAYHKSCFRCSHCHCVLTPKTFAINKNVMFC 377

Query: 72  TRDYQRLYGTR 82
           T  Y++L+ T+
Sbjct: 378 TNHYKQLFATK 410

 Score = 29.3 bits (64), Expect = 5.3,   Method: Compositional matrix adjust.
 Identities = 16/70 (22%), Positives = 27/70 (38%), Gaps = 1/70 (1%)
 Frame = +3

Query: 143 SAHVAQGLRSCGGCGLEIKNGQALVALDKHWHLGCFKCKTCGKLLNAE-YISKDGLPYCE 201
           S  VA  L  CG C   +   + +      +H  CF+C  C  +L  + +     + +C 
Sbjct: 201 SMRVAVQLEKCGACHKTVYAMEKIEIEKNAYHKSCFRCSHCHCVLTPKTFAINKNVMFCT 380

Query: 202 ADYHSKFGIR 211
             Y   F  +
Sbjct: 381 NHYKQLFATK 410
>35341
          Length = 641

 Score = 34.3 bits (77), Expect = 0.13,   Method: Compositional matrix adjust.
 Identities = 18/56 (32%), Positives = 27/56 (48%)
 Frame = +3

Query: 388 SRPGSESGRSTPSLSVHSDSRPPSSTYQQAPRHFHVPDTGVKDNIYRKPPIYKQHA 443
           +RP S S  +  +  V +  +PP    ++  R   + + GVKDN  RK  I K  A
Sbjct: 288 ARPTSTSLETMQTSEVKAVYKPPEQRSKKPLRRIEIEEIGVKDNTERKEAIAKVEA 455
>29549
          Length = 439

 Score = 30.8 bits (68), Expect = 1.7,   Method: Compositional matrix adjust.
 Identities = 11/44 (25%), Positives = 23/44 (52%)
 Frame = +3

Query: 89  FIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQ 132
           F+EG  +  + +T    C +C++ ++PF          K+C+C+
Sbjct: 279 FLEGHYLKIVIRTISNYCLLCSLIKVPFLKNGYYILKKKKCICR 410
>24891
          Length = 470

 Score = 29.6 bits (65), Expect = 3.9,   Method: Composition-based stats.
 Identities = 14/37 (37%), Positives = 23/37 (62%), Gaps = 1/37 (2%)
 Frame = -1

Query: 398 TPSLS-VHSDSRPPSSTYQQAPRHFHVPDTGVKDNIY 433
           TP+++  HSD    S TY Q   +F++ +TGV  N++
Sbjct: 446 TPTVTHTHSDIHTHSVTYTQICTNFYILETGVSCNVF 336
>01348
          Length = 1616

 Score = 28.5 bits (62), Expect = 8.4,   Method: Compositional matrix adjust.
 Identities = 23/63 (36%), Positives = 33/63 (52%), Gaps = 6/63 (9%)
 Frame = -3

Query: 1    MSAVSQPQAAHAPLEKPASTAILCNTCGNV-CKGEVLR-----VQNKYFHIRCFVCKACG 54
             SAVS    + A  +K  +  +L  TCG V C+   ++      Q+K  H  CF C+ACG
Sbjct: 1575 FSAVSDIYTSRAS-QKWQNGDLLQATCGLVKCRDTCIKDFGFMAQSKEDHFSCF-CRACG 1402

Query: 55   CDL 57
            CD+
Sbjct: 1401 CDV 1393
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|9789937|ref|NP_062768.1| DnaJ (Hsp40) homolog,
subfamily A, member 2 [Mus musculus]
         (412 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

12040                                                                 111   4e-25
14550                                                                 102   3e-22
10680                                                                  94   9e-20
20488                                                                  94   1e-19
02324                                                                  68   9e-12
07620                                                                  39   1e-08
13998                                                                  55   5e-08
26984                                                                  54   2e-07
02088                                                                  45   5e-05
22505                                                                  39   0.004
13422                                                                  36   0.031
38321                                                                  35   0.053
21879                                                                  30   1.6  
20155                                                                  28   5.9  
>12040
          Length = 1151

 Score =  111 bits (278), Expect = 4e-25,   Method: Compositional matrix adjust.
 Identities = 62/146 (42%), Positives = 85/146 (58%)
 Frame = -2

Query: 247  DIVLLLQEKEHEVFQRDGNDLHMTYKIGLVEALCGFQFTFKHLDARQIVVKYPPGKVIEP 306
            DI++LL EKEH  F   G DL M   + LVEALCGFQ   K +D R ++V   PG+VI  
Sbjct: 1150 DIIILLDEKEHSTFVHAGTDLMMKMPLQLVEALCGFQRIVKTMDDRDLLVATQPGEVIRH 971

Query: 307  GCVRVVRGEGMPQYRNPFEKGDLYIKFDVQFPENNWINPDKLSELEDLLPSRPEVPNVIG 366
               + +  EGMP ++NP EKG L I+F+V FP  + INP  +  L+  LP  PE+ ++  
Sbjct: 970  EMTKCIAEEGMPIFKNPMEKGTLIIQFEVIFP--DVINPSVIPTLKQCLPPAPEI-DIPI 800

Query: 367  ETEEVELQEFDSTRGSGGGQRREAYN 392
            E E   L++FD  +     QR  AY+
Sbjct: 799  EAEHTVLEDFDPKQRRQPNQRM-AYD 725
>14550
          Length = 1395

 Score =  102 bits (254), Expect = 3e-22,   Method: Compositional matrix adjust.
 Identities = 76/234 (32%), Positives = 111/234 (47%), Gaps = 1/234 (0%)
 Frame = -2

Query: 115 DMMHPLKVSLEDLYNGKTTKLQLSKNVLCSACSGQGGKSGAVQKCSACRGRGVRIMIRQL 174
           D++  L V+LE+LY+G   ++   K V   A     GK    +KC+ CR   +  + +QL
Sbjct: 809 DVVMDLDVTLEELYSGDFVEVLRYKPVSKPA----KGK----RKCN-CR---METVTQQL 666

Query: 175 APGMVQ-QMQSVCSDCNGEGEVINEKDRXXXXXXXXXXXXXXXLEVHVDKGMKHGQRITF 233
            PG  Q   Q VC +C     V  EK                 LEV ++ GM+ GQ   F
Sbjct: 665 GPGRFQMSQQQVCDECPNIKFVPEEK----------------VLEVEIEPGMRDGQEYPF 534

Query: 234 TGEADQAPGVEPGDIVLLLQEKEHEVFQRDGNDLHMTYKIGLVEALCGFQFTFKHLDARQ 293
             E +     EPGD+  ++++ +H  F+R G+DL+    + L +AL GF+    HLD  +
Sbjct: 533 VAEGEPHMDGEPGDLRFIIRQVKHARFERKGDDLYTNVTVSLQDALIGFEMDIVHLDGHK 354

Query: 294 IVVKYPPGKVIEPGCVRVVRGEGMPQYRNPFEKGDLYIKFDVQFPENNWINPDK 347
           + V     K+  PG       EGMP Y N   KG L+I FD+ FP+      DK
Sbjct: 353 VHVIR--DKITWPGARMRKSNEGMPNYENNNVKGSLFITFDIDFPKGTLSEEDK 198

 Score = 71.2 bits (173), Expect = 8e-13,   Method: Compositional matrix adjust.
 Identities = 34/64 (53%), Positives = 46/64 (71%), Gaps = 3/64 (4%)
 Frame = -1

Query: 9    LYDILGVPPGASENELKKAYRKLAKEYHPDKN---PNAGDKFKEISFAYEVLSNPEKREL 65
             Y ILGV   A   ++K+AYRK+AKE HPDKN   P A  +F+++  AYEVLS+ EKR++
Sbjct: 1131 FYKILGVSKSADTKQIKRAYRKIAKELHPDKNRDDPEAEQRFQDLGAAYEVLSDEEKRKV 952

Query: 66   YDRY 69
            YDR+
Sbjct: 951  YDRH 940

 Score = 35.0 bits (79), Expect = 0.053,   Method: Compositional matrix adjust.
 Identities = 16/33 (48%), Positives = 19/33 (57%)
 Frame = -1

Query: 315  EGMPQYRNPFEKGDLYIKFDVQFPENNWINPDK 347
            EGMP Y N   KG L+I FD+ FP+      DK
Sbjct: 1380 EGMPNYENNNVKGSLFITFDIDFPKGTLSEEDK 1282
>10680
          Length = 1093

 Score = 94.0 bits (232), Expect = 9e-20,   Method: Compositional matrix adjust.
 Identities = 66/224 (29%), Positives = 106/224 (47%), Gaps = 1/224 (0%)
 Frame = -3

Query: 118 HPLKVSLEDLYNGKTTKLQLSKNVLCSACSGQGGKSG-AVQKCSACRGRGVRIMIRQLAP 176
           +P KV   D + G     +    V      G GG  G   +K      R + + + ++  
Sbjct: 977 NPDKV-FRDFFGGDNPFQEFYDRVDGDLSMGFGGLHGRGSKKQDPPIERDLFLALEEVFH 801

Query: 177 GMVQQMQSVCSDCNGEGEVINEKDRXXXXXXXXXXXXXXXLEVHVDKGMKHGQRITFTGE 236
           G  ++M+      N +G   + +D+               L + V KG K G +ITF  E
Sbjct: 800 GCTKKMKISRRVMNEDGHTSSIRDKI--------------LTITVKKGWKPGTKITFPKE 663

Query: 237 ADQAPGVEPGDIVLLLQEKEHEVFQRDGNDLHMTYKIGLVEALCGFQFTFKHLDARQIVV 296
            DQ P   P DIV ++++K H  F+R+G +L  T  + L  AL G       LD R + +
Sbjct: 662 GDQGPNNVPADIVFIVKDKPHPRFRREGLNLIHTANVLLGRALTGTTVDIHTLDDRTLHI 483

Query: 297 KYPPGKVIEPGCVRVVRGEGMPQYRNPFEKGDLYIKFDVQFPEN 340
             P   +++PG  ++V GEGMP   +P +KGDL I+F+++FP +
Sbjct: 482 --PINDIVKPGYKKIVPGEGMPMSSDPTQKGDLIIEFNIEFPTS 357
>20488
          Length = 3281

 Score = 94.0 bits (232), Expect = 1e-19,   Method: Compositional matrix adjust.
 Identities = 49/124 (39%), Positives = 72/124 (58%)
 Frame = -2

Query: 217  LEVHVDKGMKHGQRITFTGEADQAPGVEPGDIVLLLQEKEHEVFQRDGNDLHMTYKIGLV 276
            L + V KG K G +ITF  E DQ P   P DIV ++++K H  F+R+G +L  T  + L 
Sbjct: 1579 LTITVKKGWKPGTKITFPKEGDQGPNNVPADIVFIVKDKPHPRFRREGLNLIHTANVLLG 1400

Query: 277  EALCGFQFTFKHLDARQIVVKYPPGKVIEPGCVRVVRGEGMPQYRNPFEKGDLYIKFDVQ 336
             AL G       LD R + +  P   +++PG  ++V GEGMP   +P ZKGDL I+F+++
Sbjct: 1399 RALTGTTVDIHTLDDRTLHI--PINDIVKPGYKKIVPGEGMPMSSDPTZKGDLIIEFNIE 1226

Query: 337  FPEN 340
            FP +
Sbjct: 1225 FPTS 1214
>02324
          Length = 2058

 Score = 67.8 bits (164), Expect = 9e-12,   Method: Compositional matrix adjust.
 Identities = 31/64 (48%), Positives = 47/64 (73%), Gaps = 4/64 (6%)
 Frame = +2

Query: 10  YDILGVPPGASENELKKAYRKLAKEYHPDKNPN----AGDKFKEISFAYEVLSNPEKREL 65
           Y++LGV   A  ++LKKAYRKLA ++HPDKNP+    A  +F+ +  AYE+L++P++R  
Sbjct: 110 YEVLGVERSADNDDLKKAYRKLALKFHPDKNPDSVEEATAQFRLVQQAYEILTDPQERSW 289

Query: 66  YDRY 69
           YDR+
Sbjct: 290 YDRH 301
>07620
          Length = 1775

 Score = 39.3 bits (90), Expect(2) = 1e-08,   Method: Compositional matrix adjust.
 Identities = 16/31 (51%), Positives = 23/31 (74%)
 Frame = +1

Query: 10  YDILGVPPGASENELKKAYRKLAKEYHPDKN 40
           Y++L V    +E+++KKAYRKLA + HPDK 
Sbjct: 106 YEVLDVKKDCTESDMKKAYRKLALQMHPDKT 198

 Score = 37.4 bits (85), Expect(2) = 1e-08,   Method: Compositional matrix adjust.
 Identities = 18/32 (56%), Positives = 22/32 (68%)
 Frame = +3

Query: 38  DKNPNAGDKFKEISFAYEVLSNPEKRELYDRY 69
           +K P A D FK+I  AY VLS+P+KR  YD Y
Sbjct: 195 NKAPGATDAFKKIGNAYSVLSDPDKRRKYDVY 290
>13998
          Length = 1075

 Score = 55.1 bits (131), Expect = 5e-08,   Method: Compositional matrix adjust.
 Identities = 29/66 (43%), Positives = 41/66 (62%), Gaps = 8/66 (12%)
 Frame = +1

Query: 10  YDILGVPPGASENELKKAYRKLAKEYHPDKNPNAGD--------KFKEISFAYEVLSNPE 61
           Y ILG+   A+E+E+KKAYRK A  +HPD++ N+          KFKE+  AY +LS+  
Sbjct: 211 YKILGISRNATEDEIKKAYRKKALVHHPDRHANSSADVRKDEELKFKEVGEAYAILSDGA 390

Query: 62  KRELYD 67
           K+  YD
Sbjct: 391 KKTRYD 408
>26984
          Length = 1107

 Score = 53.5 bits (127), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 26/62 (41%), Positives = 40/62 (64%), Gaps = 2/62 (3%)
 Frame = -2

Query: 10  YDILGVPPGASENELKKAYRKLAKEYHPDKN--PNAGDKFKEISFAYEVLSNPEKRELYD 67
           Y ILG+   AS+ ++K+ YR+ A   HPDKN  P A + FK +  A+E++ +P KR+ YD
Sbjct: 509 YSILGLRADASDEDIKRYYRRQAVLVHPDKNQEPGAEEAFKILGHAFEMIGDPTKRKEYD 330

Query: 68  RY 69
            +
Sbjct: 329 TH 324
>02088
          Length = 1062

 Score = 45.1 bits (105), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 24/66 (36%), Positives = 37/66 (56%), Gaps = 5/66 (7%)
 Frame = +3

Query: 7   TKLYDILGVPPGASENELKKAYRKLAKEYHPDK-----NPNAGDKFKEISFAYEVLSNPE 61
           T LY+++G+   A+  E+KK Y K++   HPD+        A  KF+ +   Y VLS+ +
Sbjct: 105 TDLYEVIGIRREATPQEVKKGYHKVSLAVHPDQVSAAEKETATRKFQTLGKVYTVLSDKD 284

Query: 62  KRELYD 67
           KR  YD
Sbjct: 285 KRAXYD 302
>22505
          Length = 784

 Score = 38.9 bits (89), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 21/50 (42%), Positives = 30/50 (60%)
 Frame = -1

Query: 3   NVADTKLYDILGVPPGASENELKKAYRKLAKEYHPDKNPNAGDKFKEISF 52
           ++    LY ILGV P A+E ++ KAYRK A + HPDK        K+++F
Sbjct: 667 DIMKMDLYGILGVGPEANEKQIVKAYRKKALKCHPDKTQTI---LKQLNF 527

 Score = 30.8 bits (68), Expect = 0.94,   Method: Compositional matrix adjust.
 Identities = 15/32 (46%), Positives = 21/32 (65%)
 Frame = -3

Query: 36  HPDKNPNAGDKFKEISFAYEVLSNPEKRELYD 67
           +PD NP A + F E+S A EVL++P  +  YD
Sbjct: 557 NPD-NPKAAELFHELSKALEVLTDPSAKAAYD 465
>13422
          Length = 930

 Score = 35.8 bits (81), Expect = 0.031,   Method: Compositional matrix adjust.
 Identities = 24/69 (34%), Positives = 35/69 (50%), Gaps = 11/69 (15%)
 Frame = +1

Query: 10  YDILGVPP---GASENELKKAYRKLAKEYHPDKNPNAG--------DKFKEISFAYEVLS 58
           Y +LG+      A+ + +K+ YR+    +HPDK    G        D F  IS AYE+L 
Sbjct: 343 YAVLGLSKLRYKATADHIKRIYRQKVLLHHPDKRRARGLHVENGENDYFLCISRAYEILG 522

Query: 59  NPEKRELYD 67
           +P KR  +D
Sbjct: 523 DPVKRRSFD 549
>38321
          Length = 1059

 Score = 35.0 bits (79), Expect = 0.053,   Method: Compositional matrix adjust.
 Identities = 16/33 (48%), Positives = 19/33 (57%)
 Frame = -1

Query: 315  EGMPQYRNPFEKGDLYIKFDVQFPENNWINPDK 347
            EGMP Y N   KG L+I FD+ FP+      DK
Sbjct: 1044 EGMPNYENNNVKGSLFITFDIDFPKGTLSEEDK 946
>21879
          Length = 353

 Score = 30.0 bits (66), Expect = 1.6,   Method: Composition-based stats.
 Identities = 12/26 (46%), Positives = 18/26 (69%)
 Frame = -3

Query: 3   NVADTKLYDILGVPPGASENELKKAY 28
           ++ D KLY ++ VPPGA ++E  K Y
Sbjct: 135 HIQDAKLYTLVSVPPGAWQHEGSKHY 58
>20155
          Length = 484

 Score = 28.5 bits (62), Expect = 5.9,   Method: Compositional matrix adjust.
 Identities = 12/28 (42%), Positives = 20/28 (71%)
 Frame = +1

Query: 12  ILGVPPGASENELKKAYRKLAKEYHPDK 39
           ILGV P AS+ ++K A++++    HPD+
Sbjct: 151 ILGVSPSASKVKIKDAHKRIMLLNHPDR 234
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|34610235|ref|NP_918943.1| reticulon 4 isoform A [Mus
musculus]
         (1162 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

19825                                                                 113   6e-25
>19825
          Length = 642

 Score =  113 bits (282), Expect = 6e-25,   Method: Compositional matrix adjust.
 Identities = 47/127 (37%), Positives = 75/127 (59%)
 Frame = +3

Query: 975  VVDLLYWRDIKKTGXXXXXXXXXXXXXXXXXXXXXTAYIALALLSVTISFRIYKGVIQAI 1034
            V+DL+YWRD++KTG                      AY++LA+L+VT+SFR+YK ++ A+
Sbjct: 258  VLDLIYWRDVRKTGVVFGCMMLVLLSLACFSLMSVLAYLSLAVLTVTLSFRLYKNIMAAV 437

Query: 1035 QKSDEGHPFRAYLESEVAISEELVQKYSNSALGHVNSTIKEXXXXXXXXXXXXXXKFAVL 1094
            QKS++GHPF+ YL+ ++ + EE V + + + L HVN ++ E              KF +L
Sbjct: 438  QKSNDGHPFKQYLDLDITLKEERVSRVTQTVLQHVNRSLLELRRLFLIEDLVDSIKFGLL 617

Query: 1095 MWVFTYV 1101
            +WV TY+
Sbjct: 618  LWVLTYI 638
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|94386155|ref|XP_986298.1| PREDICTED: myosin IXa
isoform 2 [Mus musculus]
         (2631 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

25922                                                                 114   6e-25
12558                                                                  85   4e-16
29397                                                                  77   1e-13
17428                                                                  74   7e-13
03745                                                                  67   9e-11
17558                                                                  63   1e-09
19361                                                                  63   1e-09
11945                                                                  52   8e-09
21189                                                                  53   2e-06
35187                                                                  49   4e-05
11353                                                                  47   8e-05
25445                                                                  46   3e-04
22804                                                                  43   0.002
30605                                                                  41   0.007
20840                                                                  31   6.1  
>25922
          Length = 422

 Score =  114 bits (285), Expect = 6e-25,   Method: Composition-based stats.
 Identities = 58/142 (40%), Positives = 85/142 (59%)
 Frame = -2

Query: 464 EMLFEALVTRKTVTVGEKLILPYKLAEAVTVRNSMAKSLYSALFDWIVFRINHALLNSKD 523
           + L  AL+ R     G+ +     ++E+   R+++ K+LYS +F W+V RIN    +S  
Sbjct: 415 DTLAHALMHRTVAVKGDMVTTDLSVSESSYARDALCKALYSRMFSWLVHRIN----DSIK 248

Query: 524 LEQDTKTLSIGVLDIFGFEDYENNSFEQFCINFANERLQHYFNQHIFKLEQEEYRTEGIS 583
           +    +T  +GVLDI+GFE +ENNSFEQF IN+ NE+LQ  F +   K EQEEY  EGI 
Sbjct: 247 VRGAQRTKVMGVLDIYGFEVFENNSFEQFIINYCNEKLQQIFIELTLKEEQEEYIKEGIE 68

Query: 584 WHNIDYIDNTCCINLISKKPTG 605
           W +++Y +N     LI K  +G
Sbjct: 67  WIHVEYFNNAVICELIEKSVSG 2
>12558
          Length = 720

 Score = 84.7 bits (208), Expect = 4e-16,   Method: Compositional matrix adjust.
 Identities = 49/132 (37%), Positives = 77/132 (58%), Gaps = 5/132 (3%)
 Frame = -1

Query: 2166 TEGIYRKSGSTNKIKELRQGLDTDAESVNLDD-----YNIHVIASVFKQWLRDLPNPLMT 2220
             +G+YR SG T+ I++LR   D D ++  L D      +IH I+S+ K + R+LPNPL+T
Sbjct: 717  VDGLYRLSGVTSNIQKLRVAFDED-QAPELSDNVQYLQDIHSISSLLKMYFRELPNPLLT 541

Query: 2221 FELYEEFLRAMGLQERKETIRGVYSVIDQLSRTHLNTLERLIFHLVRIALQEDTNRMSAN 2280
            ++LY +F  A  +++    +  ++ V+ QL   H  TLE L+ HL  +A       M + 
Sbjct: 540  YQLYTQF--ADAVKDEDNRLLRIHDVVQQLPPPHYRTLEYLVRHLACVASYGLQTGMHSK 367

Query: 2281 ALAIVFAPCILR 2292
             LAIV+AP +LR
Sbjct: 366  NLAIVWAPNLLR 331
>29397
          Length = 401

 Score = 76.6 bits (187), Expect = 1e-13,   Method: Compositional matrix adjust.
 Identities = 35/87 (40%), Positives = 58/87 (66%)
 Frame = -2

Query: 2267 RIALQEDTNRMSANALAIVFAPCILRCPDTTDPLQSVQDISKTTTCVELIVVEQMNKYKA 2326
            ++A+ E++ +MS N LAI+FAPC+LR        +S+  + K T C+E+I+ E++   KA
Sbjct: 400  KVAMHEESTKMSVNGLAIIFAPCLLRSNKEMQAQESLNQVPKQTRCMEVILSEELATVKA 221

Query: 2327 RLKDISSLEFAENKAKTRLSLIRRSMK 2353
            +L DI++LE AE  A+ RL  +R S++
Sbjct: 220  KLADITTLESAEQTAEERLFHVRASLR 140
>17428
          Length = 623

 Score = 74.3 bits (181), Expect = 7e-13,   Method: Compositional matrix adjust.
 Identities = 45/154 (29%), Positives = 89/154 (57%), Gaps = 2/154 (1%)
 Frame = +1

Query: 2167 EGIYRKSGSTNKIKELRQGLDTDAESVNLDDY--NIHVIASVFKQWLRDLPNPLMTFELY 2224
            EG++R S  + K ++L+   D  A  V+++++  + + +A V KQ+LR+LP P++TF+LY
Sbjct: 1    EGLFRFSRISFKDEKLKACFD--ARLVDMEEFSNDPNTVAGVMKQYLRELPEPMLTFDLY 174

Query: 2225 EEFLRAMGLQERKETIRGVYSVIDQLSRTHLNTLERLIFHLVRIALQEDTNRMSANALAI 2284
             +F+RA  L   ++  + +Y+++++L  ++ N    LI  L  +A +   N+M+ + LAI
Sbjct: 175  PDFMRAAQLGHDQKC-QSLYTLVNRLPPSNFNNFRYLIKFLALLAEKSHVNKMTPSNLAI 351

Query: 2285 VFAPCILRCPDTTDPLQSVQDISKTTTCVELIVV 2318
            V  P +L       P  ++   S  ++ +E  V+
Sbjct: 352  VMGPNLLWARGENTP--NMMTASTVSSIIETFVL 447
>03745
          Length = 1266

 Score = 67.0 bits (162), Expect = 9e-11,   Method: Compositional matrix adjust.
 Identities = 41/131 (31%), Positives = 70/131 (53%), Gaps = 2/131 (1%)
 Frame = +1

Query: 1912 VKISSVALDSMHWQNDSVQIIASASDLKSMDEFLLKKMNDLDNEDSKKDTLVDVVFKKAL 1971
            VKIS  +     WQ      I    DL  +DEF+ +K  +L  + +  DTL D +FK +L
Sbjct: 826  VKISRTS----EWQYADDLKITDVLDLHQLDEFISQKGRELFKDGAHSDTLFDKIFKGSL 993

Query: 1972 KEFRQNIFSSYSSALAMDDGKSIRYKDLYALFEQILEKTMRLEQ--RDWNESPVRVWVNT 2029
             EF + + +  +  +  ++   ++Y+DL+  F Q+L   M+ +Q      E+PV + +N 
Sbjct: 994  DEFGRELKTVIAIEMQHEE-VLVKYRDLFDKFRQVLTAEMKKQQSHEQQTEAPVVMALNA 1170

Query: 2030 FKVFLDEYMNE 2040
            F+ FLDE+M +
Sbjct: 1171 FRGFLDEFMKQ 1203
>17558
          Length = 671

 Score = 63.2 bits (152), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 38/153 (24%), Positives = 72/153 (47%), Gaps = 2/153 (1%)
 Frame = +3

Query: 2148 VPLVVEKLINYIEMHGLYTEGIYRKSGSTNKIKELRQGLDT--DAESVNLDDYNIHVIAS 2205
            +PL+++  I  I ++GL+ +G++R SG+  +I   +   ++  DA    +D  +++ IA 
Sbjct: 102  IPLIIKGCIRVINLYGLHHQGVFRVSGAQVEINHFKNVFESGDDALVDVVDASDMNSIAG 281

Query: 2206 VFKQWLRDLPNPLMTFELYEEFLRAMGLQERKETIRGVYSVIDQLSRTHLNTLERLIFHL 2265
            V K + R+L  PL    L++  +      +    +  +  ++  L R+    +  L   L
Sbjct: 282  VLKLYFRELREPLFPLHLFDALVECTRENDVHRRLERIKDLLATLPRSVFVVMRYLFAFL 461

Query: 2266 VRIALQEDTNRMSANALAIVFAPCILRCPDTTD 2298
              ++   D N M    LAI F P +L  P   D
Sbjct: 462  NHLSEYSDENMMDPYNLAICFGPTLLPIPPDRD 560
>19361
          Length = 685

 Score = 63.2 bits (152), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 36/116 (31%), Positives = 62/116 (53%), Gaps = 4/116 (3%)
 Frame = -1

Query: 2065 DLVEEHNGHIFKATQYSIPTYCEYCSSLIW-IMDRASVCKLCKYACHKKCCLKTTAKC-- 2121
            D  +    H+FK   ++   +CE C++ +W ++ +   C+ C    HKKC  +   +C  
Sbjct: 340  DWTQYEKPHVFKVQNFNGLNWCELCANFMWGLIAQGVKCQDCGVQTHKKCSERMPNECMP 161

Query: 2122 SKKYDPELSSRQFGVELSRLTSEDRAV-PLVVEKLINYIEMHGLYTEGIYRKSGST 2176
            + KY      R +GV+L+ +T  ++ + P+VVE  I  IE  G+  EG+YR + ST
Sbjct: 160  NMKY----VKRLYGVDLTTVTKANKQILPIVVEXCIKEIEKRGVEPEGLYRLAXST 5
>11945
          Length = 1161

 Score = 52.0 bits (123), Expect(2) = 8e-09,   Method: Compositional matrix adjust.
 Identities = 34/126 (26%), Positives = 64/126 (50%), Gaps = 2/126 (1%)
 Frame = -1

Query: 2171 RKSGSTNKIKELRQGLDTD--AESVNLDDYNIHVIASVFKQWLRDLPNPLMTFELYEEFL 2228
            R  GS  ++K+LR  L+      + N  +   +  A++ KQ+LR+LP PL+T++  E F 
Sbjct: 417  RVPGSVTRVKQLRHELEEKFYQNTFNWGEVMPNDCAALLKQFLRELPTPLLTYDYLEAFP 238

Query: 2229 RAMGLQERKETIRGVYSVIDQLSRTHLNTLERLIFHLVRIALQEDTNRMSANALAIVFAP 2288
            +   + +  E ++ +  ++  L   H + L+ L+  L  I    DTN+M  N + ++ A 
Sbjct: 237  QVENIPKTLEQLKALNLLVLLLPTEHRDVLKVLLRFLRNIVSHSDTNKMGLNNICMIMAQ 58

Query: 2289 CILRCP 2294
             +   P
Sbjct: 57   ILFIAP 40

 Score = 28.5 bits (62), Expect(2) = 8e-09,   Method: Composition-based stats.
 Identities = 16/42 (38%), Positives = 23/42 (54%), Gaps = 6/42 (14%)
 Frame = -3

Query: 2134 FGVELSRLTSEDRA------VPLVVEKLINYIEMHGLYTEGI 2169
            FGV L  L   D+       VPL  +KL++++E  G+  EGI
Sbjct: 547  FGVPLPVLLEHDQKHXPGVRVPLFFQKLVDHLEREGVGMEGI 422
>21189
          Length = 461

 Score = 53.1 bits (126), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 31/103 (30%), Positives = 56/103 (54%), Gaps = 2/103 (1%)
 Frame = +3

Query: 2127 PELSSRQ-FGVELSR-LTSEDRAVPLVVEKLINYIEMHGLYTEGIYRKSGSTNKIKELRQ 2184
            P+ S +  FGV  +  L    + +P  V   + Y+        GI+RKSG  ++I +LR 
Sbjct: 153  PQFSDKNVFGVPFTVILQRTGQPLPQCVLYAMRYLRKTSHDAVGIFRKSGVRSRIHKLRD 332

Query: 2185 GLDTDAESVNLDDYNIHVIASVFKQWLRDLPNPLMTFELYEEF 2227
             +++  ++VN D+   + +A + KQ+ R+LP  L+T +L + F
Sbjct: 333  MVESCPDTVNFDELQPYDVADLLKQYFRELPECLLTTKLSDTF 461
>35187
          Length = 593

 Score = 48.5 bits (114), Expect = 4e-05,   Method: Composition-based stats.
 Identities = 16/53 (30%), Positives = 29/53 (54%), Gaps = 1/53 (1%)
 Frame = -3

Query: 2071 NGHIFKATQYSIPTYCEYCSSLIW-IMDRASVCKLCKYACHKKCCLKTTAKCS 2122
            +GH F    +  PTYC +C+ ++W ++    VC++C +  H +C     + CS
Sbjct: 321  HGHFFTKKTFHKPTYCHHCTDILWGLIGVGYVCEVCNFVVHDRCMKTVVSPCS 163
>11353
          Length = 454

 Score = 47.4 bits (111), Expect = 8e-05,   Method: Compositional matrix adjust.
 Identities = 25/74 (33%), Positives = 34/74 (45%), Gaps = 1/74 (1%)
 Frame = +1

Query: 2073 HIFKATQYSIPTYCEYCSSLIWIMDRASV-CKLCKYACHKKCCLKTTAKCSKKYDPELSS 2131
            H F+   Y+ PTYC++C  L+W   +    C  C Y CH KC       CSK      +S
Sbjct: 142  HRFEKYTYTTPTYCDFCQQLLWGFSKTGTHCVDCGYNCHDKCQPLVPKTCSKLKSVSDTS 321

Query: 2132 RQFGVELSRLTSED 2145
             Q  V ++R    D
Sbjct: 322  AQSAVIVTRSGVSD 363
>25445
          Length = 460

 Score = 45.8 bits (107), Expect = 3e-04,   Method: Composition-based stats.
 Identities = 18/44 (40%), Positives = 27/44 (61%), Gaps = 1/44 (2%)
 Frame = -1

Query: 2071 NGHIFKATQYSIPTYCEYCSSLIW-IMDRASVCKLCKYACHKKC 2113
            N H FKA  Y  PT+C++C SL++ ++ +   C  C   CHK+C
Sbjct: 403  NLHKFKAHTYGSPTFCDHCGSLLYGLIHQGLKCDSCDMNCHKRC 272
>22804
          Length = 967

 Score = 43.1 bits (100), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 20/52 (38%), Positives = 26/52 (50%), Gaps = 1/52 (1%)
 Frame = -3

Query: 2073 HIFKATQYSIPTYCEYCSSLIWIMDRASV-CKLCKYACHKKCCLKTTAKCSK 2123
            H F+   Y+ PTYC++C  L+W   +    C  C Y CH KC       CSK
Sbjct: 830  HRFEKYTYTTPTYCDFCQQLLWGFSKTGTHCVDCGYNCHDKCQPLVPKTCSK 675
>30605
          Length = 336

 Score = 40.8 bits (94), Expect = 0.007,   Method: Composition-based stats.
 Identities = 34/113 (30%), Positives = 59/113 (52%), Gaps = 8/113 (7%)
 Frame = -3

Query: 393 EDLRHDFERLQLAMEMVGFLPKTRRQIFSLLSAILHLGNISYKKKTYRDDSIDICN---- 448
           +D+R DF+    AM  +G     +  IF L++A+LHLGNI+++     DD+   C     
Sbjct: 331 DDVR-DFKVCDEAMTRMGVSDADKMAIFMLVAAVLHLGNIAFEDD--HDDTKGGCKVLEE 161

Query: 449 -PEVLPIVSELLEVKEEMLFEALVTRKTVTVGEK---LILPYKLAEAVTVRNS 497
             + L   + LL V +  L ++L +R   + G K   + +P K +EA + R++
Sbjct: 160 AEDSLATAAVLLGVDKMELRDSLTSRIMQSGGIKGSAIKVPLKPSEASSARDA 2
>20840
          Length = 861

 Score = 31.2 bits (69), Expect = 6.1,   Method: Compositional matrix adjust.
 Identities = 15/40 (37%), Positives = 26/40 (65%)
 Frame = +1

Query: 1119 AATCIQSRWRGYRQRKKYKEQRNKIILLQSIYRGFRARQR 1158
            AA  IQS +R Y+Q   YK+  +  +L+Q+ +R + A++R
Sbjct: 28   AAVLIQSYYRRYKQYAYYKKMTHAAVLIQNQFRSYSAQKR 147
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|21314824|ref|NP_079657.1| ATPase, H+ transporting,
lysosomal V1 subunit F [Mus musculus]
         (119 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

31996                                                                 108   7e-25
01608                                                                  26   3.5  
01203                                                                  26   3.5  
21491                                                                  25   8.1  
>31996
          Length = 595

 Score =  108 bits (269), Expect = 7e-25,   Method: Compositional matrix adjust.
 Identities = 52/93 (55%), Positives = 66/93 (70%)
 Frame = +1

Query: 5   GKLIAVIGDEDTVTGFLLGGIGELNKNRHPNFLVVEKDTTINEIEDTFRQFLNRDDIGII 64
           GKLI+VIGDEDT TGF++GGIGELNK+R PN++VV KDT   EIE+TF+ F         
Sbjct: 313 GKLISVIGDEDTCTGFIVGGIGELNKHRVPNYMVVNKDTPAMEIEETFKSFSET*RHCHN 492

Query: 65  LINQYIAEMVRHALDAHQRSIPAVLEIPSKEHP 97
           LINQ+IAE++RH +D H   IPA    P++  P
Sbjct: 493 LINQHIAELIRHVIDQHSSPIPACWRSPARTVP 591

 Score = 26.9 bits (58), Expect = 2.0,   Method: Compositional matrix adjust.
 Identities = 11/16 (68%), Positives = 13/16 (81%)
 Frame = +3

Query: 83  RSIPAVLEIPSKEHPY 98
           +S P VLEIPSK+ PY
Sbjct: 546 QSYPGVLEIPSKDCPY 593
>01608
          Length = 1644

 Score = 26.2 bits (56), Expect = 3.5,   Method: Composition-based stats.
 Identities = 10/21 (47%), Positives = 16/21 (76%)
 Frame = +2

Query: 28  LNKNRHPNFLVVEKDTTINEI 48
           LN+N++  F+VV KDT + +I
Sbjct: 632 LNENKYKQFVVVTKDTLLKQI 694
>01203
          Length = 1520

 Score = 26.2 bits (56), Expect = 3.5,   Method: Compositional matrix adjust.
 Identities = 10/21 (47%), Positives = 16/21 (76%)
 Frame = +3

Query: 28   LNKNRHPNFLVVEKDTTINEI 48
            LN+N++  F+VV KDT + +I
Sbjct: 1269 LNENKYKQFVVVTKDTLLKQI 1331
>21491
          Length = 376

 Score = 25.0 bits (53), Expect = 8.1,   Method: Compositional matrix adjust.
 Identities = 15/57 (26%), Positives = 26/57 (45%)
 Frame = -2

Query: 35  NFLVVEKDTTINEIEDTFRQFLNRDDIGIILINQYIAEMVRHALDAHQRSIPAVLEI 91
           N L   K   ++E+ DT   F+N D    +++ QY+     H   +HQR   +   +
Sbjct: 210 NVLGFSKLARLSELFDTVN*FMNADST*PVIMAQYLTTNSTH---SHQRVFLSAFSV 49
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|84781690|ref|NP_001028526.1| IQ motif and Sec7 domain
3 [Mus musculus]
         (1195 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

30249                                                                 112   7e-25
17498                                                                  32   1.1  
04641                                                                  32   1.5  
02977                                                                  30   6.8  
>30249
          Length = 822

 Score =  112 bits (281), Expect = 7e-25,   Method: Compositional matrix adjust.
 Identities = 59/151 (39%), Positives = 89/151 (58%), Gaps = 10/151 (6%)
 Frame = -2

Query: 751 EAQKVERLIEAFSQRYCMCNPEVVQQFHNPDTXXXXXXXXXXXNTDMYSPNIKPDRKMML 810
           EAQK+ERL+EAF++RYC CNP+ V+ F   DT           NTD+++ ++KP+RKM L
Sbjct: 821 EAQKIERLMEAFAERYCQCNPDQVKNFKTFDTVFLLAFAIIMLNTDLHNSSVKPERKMKL 642

Query: 811 EDFIRNLRGVDDGADIPRELVVGIYERIQQKELKSNE----------DHVTYVTKVEKSI 860
           EDF+RNLRG+DDG D+  +L          ++L++N+           H  +  + +   
Sbjct: 641 EDFVRNLRGIDDGEDVDGDLA--------SRDLRANQAAGVQGRGRPGHAGHEGRTD-HC 489

Query: 861 VGMKTVLSMPHRRLVCCSRLFEVTDVNKLQK 891
              +  L++ HRRLVC  RL+EV D NK ++
Sbjct: 488 GWQEPQLALSHRRLVCYCRLYEVHDPNKRKR 396

 Score = 92.4 bits (228), Expect = 1e-18,   Method: Compositional matrix adjust.
 Identities = 68/194 (35%), Positives = 100/194 (51%), Gaps = 8/194 (4%)
 Frame = -3

Query: 815  RNLRGVDDGADIPR----ELVVGIYERIQQKELKSNEDHVTYVTKVEKSIVGMKT----V 866
            + L G  +G    R      + GIYERI+Q+E K+  D VT V KVE++IVG K      
Sbjct: 640  KTLSGTSEGLTTGRMWTGTWLAGIYERIKQQEFKAGVDQVTQVMKVEQTIVGGKNPNWPC 461

Query: 867  LSMPHRRLVCCSRLFEVTDVNKLQKQAAHQREVFLFNDLLVILKLCPKKKSSFTYTFCKA 926
            L+      V C+R    T   K +  +A  R + +         L  +KK+  TY F  +
Sbjct: 460  LTGAWCATVACTRSMTPT---KGKDWSAPTRSLPV*RHSSGDENL-QQKKTGITYNFKIS 293

Query: 927  VGLLGMRFHLFENEYYSHGITLATPLSGSEKKQVLHFCALGSDEMQKFVEDLKESIAEVT 986
            + L GM+ +LFE  +Y +G+ L   +   + K ++ F A    + QKFVEDLKESI E  
Sbjct: 292  LSLCGMQVYLFETPHYHYGVQLTNNI---DSKPLITFNARNDHDRQKFVEDLKESILETN 122

Query: 987  ELEQIRIEWELEKQ 1000
             +EQ+RIE E+ + 
Sbjct: 121  GMEQLRIEEEMHRH 80
>17498
          Length = 494

 Score = 32.3 bits (72), Expect = 1.1,   Method: Composition-based stats.
 Identities = 13/39 (33%), Positives = 24/39 (61%), Gaps = 5/39 (12%)
 Frame = -1

Query: 918 SFTYTFCKAVGLLGMRFHL-----FENEYYSHGITLATP 951
           SFT++FC ++G LG++ HL     F+N ++      ++P
Sbjct: 323 SFTWSFCLSLGFLGLKLHLLFVV*FKNFHFMRSDGFSSP 207
>04641
          Length = 845

 Score = 32.0 bits (71), Expect = 1.5,   Method: Composition-based stats.
 Identities = 16/40 (40%), Positives = 24/40 (60%)
 Frame = -3

Query: 856 VEKSIVGMKTVLSMPHRRLVCCSRLFEVTDVNKLQKQAAH 895
           VE S V +  +LS+P   LVCC   + V +V K +K+ A+
Sbjct: 441 VESSFVFVIVLLSLPVPYLVCCQIYYPVINVGK*KKKTAY 322
>02977
          Length = 2336

 Score = 29.6 bits (65), Expect = 6.8,   Method: Compositional matrix adjust.
 Identities = 13/39 (33%), Positives = 24/39 (61%), Gaps = 5/39 (12%)
 Frame = -2

Query: 918  SFTYTFCKAVGLLGMRFHL-----FENEYYSHGITLATP 951
            SFT++FC ++G LG++ HL     F+N ++      ++P
Sbjct: 1186 SFTWSFCLSLGFLGLKLHLLFVV*FKNFHFMRSDGFSSP 1070
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|139948827|ref|NP_001008498.2| WD repeat domain 34
[Mus musculus]
         (537 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

12841                                                                 111   9e-25
14105                                                                  55   7e-08
01768                                                                  54   1e-07
07741                                                                  50   2e-06
13278                                                                  45   6e-05
20662                                                                  44   1e-04
08355                                                                  40   0.003
02960                                                                  37   0.016
00825                                                                  37   0.018
01598                                                                  35   0.066
37142                                                                  35   0.093
03387                                                                  35   0.10 
01748                                                                  33   0.27 
12780                                                                  32   0.91 
04395                                                                  31   0.97 
19949                                                                  31   1.0  
13890                                                                  31   1.4  
07474                                                                  30   2.0  
23118                                                                  28   7.2  
30295                                                                  28   8.9  
>12841
          Length = 1364

 Score =  111 bits (277), Expect = 9e-25,   Method: Compositional matrix adjust.
 Identities = 96/345 (27%), Positives = 156/345 (45%), Gaps = 14/345 (4%)
 Frame = +1

Query: 150 LHTLVYPLAQGQGLHVTGISWNSTG-SVLACAYGRLDDGDWSTLKS-YVCTWNLDRQGLN 207
           L + V PL +G+  +V+ ++WN +   ++A  YG+ D   ++  KS  +C W+L     N
Sbjct: 370 LWSYVCPLTKGR--NVSCLAWNKSNPDLVAVGYGQFD---FTNQKSGLICCWSLK----N 522

Query: 208 XXXXXXXXXXXXXXMCLAFHPTQPSHIAGGLYSGEVLVWDMSRPEDPLLWRTGLTDDTHT 267
                           L F     + +A G Y G V ++++    D  +     T   H 
Sbjct: 523 PEYPERVYTSTHGVTSLDFSVANANILAAGYYDGGVAIYNVRSTSDEPILDNQETHGKHL 702

Query: 268 DPVYQVLWLPEPRHS--HRFQVL-SAATDGKVLLWRGSGAGQLRLTKGFA----LAVQQL 320
            PV+Q+ W+ + R S   R +VL S +TDG+V  W         + KGF     + +++L
Sbjct: 703 GPVWQIQWIEKERGSGEERAEVLISISTDGRVTQWS--------IRKGFESNNIMRLKKL 858

Query: 321 P-RSTKLKKPPRGETEV----GVTSVAFSSFDSSLFVLGTEGGFPLKCSLASEVAALTRM 375
           P R     +  +GE  +    G     F S D ++++ GTE G+  KCS +     L   
Sbjct: 859 PTRMAGKAREKKGEAFISRHAGGLCFDFHSRDLNVYLAGTEEGYIHKCSCSYNEQYLE-- 1032

Query: 376 PSSVPLRAPVQFTFSPHGGPVYSVSCSPFHRNLFLSAGTDGHVHLYSMLQAQPLTSLQLS 435
                       T+S H  PVY +  SPF  ++FLS   D  + L+   +  P+ +   S
Sbjct: 1033------------TYSGHTAPVYHIRWSPFVSDIFLSCSADWSIRLWHQDRTTPILTFHSS 1176

Query: 436 HKYLFAVRWSPVRPLVFAAASGEGDVQLFDLQKSSQKPTVSITQT 480
            K +  V WSP    VFA    EG V+++DL +S+    ++IT T
Sbjct: 1177TKTVHDVCWSPRSSTVFACVH-EGAVEVWDLAQSTLDAVITITPT 1308
>14105
          Length = 429

 Score = 55.1 bits (131), Expect = 7e-08,   Method: Compositional matrix adjust.
 Identities = 30/95 (31%), Positives = 50/95 (52%)
 Frame = +3

Query: 420 LYSMLQAQPLTSLQLSHKYLFAVRWSPVRPLVFAAASGEGDVQLFDLQKSSQKPTVSITQ 479
           L+S+   +PL S + +  Y+  V WSPV P +FAA  G G + L++L + ++ PT SI  
Sbjct: 3   LWSLKDTKPLYSFEDNSDYVMDVAWSPVHPALFAAVDGSGRLDLWNLNQDTEVPTASI-- 176

Query: 480 TQDGSPVYCLEFNSQQTQLLAAGDAKGMVKVWQLS 514
             DG+P       +     +  GD  G + V+ ++
Sbjct: 177 VVDGAPALNRVSWTPSGLHVTIGDESGKLYVYDVA 281
>01768
          Length = 1424

 Score = 54.3 bits (129), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 32/132 (24%), Positives = 61/132 (46%), Gaps = 5/132 (3%)
 Frame = +3

Query: 388 TFSPHGGPVYSVSCSPFHRNLFLSAGTDGHVHLYSMLQ----AQPLTSLQLSHKYLFAVR 443
           +++ H   V  V  SP   N+F S   D  + +++  Q    A  LT  +   + +  + 
Sbjct: 822 SYAAHTDSVEDVQWSPNEGNVFASCSVDRTLRIWNTQQKPSKANVLTVPEAHSRDINVIN 1001

Query: 444 WSPVRPLVFAAASGEGDVQLFDLQKSSQKPTVSITQTQ-DGSPVYCLEFNSQQTQLLAAG 502
           W+P+   + A+   +G ++++DL+    KP  +    +    PV  LE+N Q + +LAA 
Sbjct: 1002WNPIEKHLLASGGDDGIIKIWDLRMFRNKPVSAQASFKLHSQPVTSLEWNPQDSSVLAAS 1181

Query: 503 DAKGMVKVWQLS 514
                + +W  S
Sbjct: 1182GEDDQITIWDFS 1217

 Score = 44.7 bits (104), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 30/137 (21%), Positives = 62/137 (45%), Gaps = 8/137 (5%)
 Frame = +3

Query: 385 VQFTFSPHGGPVYSVSCSPFHRNLFLSAGTDGHVHLYSMLQAQPLTSLQLSHKYLFA--- 441
           +  T + H    +++  SP  +   ++    G +++     +QP +S   + K  +A   
Sbjct: 675 IVHTVTHHTTEGFAIDWSPAAKGWLVTGDCTGAIYI-----SQPSSSGWTTEKSSYAAHT 839

Query: 442 -----VRWSPVRPLVFAAASGEGDVQLFDLQKSSQKPTVSITQTQDGSPVYCLEFNSQQT 496
                V+WSP    VFA+ S +  +++++ Q+   K  V          +  + +N  + 
Sbjct: 840 DSVEDVQWSPNEGNVFASCSVDRTLRIWNTQQKPSKANVLTVPEAHSRDINVINWNPIEK 1019

Query: 497 QLLAAGDAKGMVKVWQL 513
            LLA+G   G++K+W L
Sbjct: 1020HLLASGGDDGIIKIWDL 1070
>07741
          Length = 2119

 Score = 50.1 bits (118), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 46/188 (24%), Positives = 78/188 (41%), Gaps = 12/188 (6%)
 Frame = +1

Query: 339 TSVAFSSFDSSLFVLGTEGGFPLKCSLASEVAALTRMPSSVPLRAPVQFTFSPHGGPVYS 398
           T+  F      LF++GTE G    CS A     +               T   H   VY 
Sbjct: 121 TAFDFHKQKDYLFLVGTEEGKVHVCSKAYTSHFID--------------TLDSHNMAVYK 258

Query: 399 VSCSPFHRNLFLSAGTDGHVHLY-----------SMLQAQPLTSLQLSHKYLFAVRWSPV 447
           V+ + +H  ++ +   D +V ++             L  +PL S  L++  +  V W+P 
Sbjct: 259 VAWNHYHPKIYATCSADWNVKIWENGGKPTDTGXDSLSRKPLFSFDLNNS-VGDVAWAPY 435

Query: 448 RPLVFAAASGEGDVQLFDLQKSSQKPTVS-ITQTQDGSPVYCLEFNSQQTQLLAAGDAKG 506
              VFAA + +G V ++DL  +  +P    +   +  + +  +EFN     +L  GD +G
Sbjct: 436 SSTVFAAVTADGKVCVYDLSVNKYEPLCEQMVAQKKKTKLTHIEFNPSY-PILIVGDDRG 612

Query: 507 MVKVWQLS 514
            V   +LS
Sbjct: 613 NVTSLKLS 636
>13278
          Length = 870

 Score = 45.4 bits (106), Expect = 6e-05,   Method: Compositional matrix adjust.
 Identities = 29/105 (27%), Positives = 54/105 (51%), Gaps = 8/105 (7%)
 Frame = +1

Query: 420 LYSMLQAQPLTSLQLSHKYLFAVRWSPVRP--------LVFAAASGEGDVQLFDLQKSSQ 471
           ++SM +   +  LQL+ K ++ ++WSP  P        L+ A+AS +  V+L+++++   
Sbjct: 1   IWSMGKDSCIHDLQLTTKEIYTIKWSPTGPGTSNPNTSLILASASFDSTVRLWEVERGLC 180

Query: 472 KPTVSITQTQDGSPVYCLEFNSQQTQLLAAGDAKGMVKVWQLSTA 516
             T+    T+   PVY + F S   + LA+G     V +W + T 
Sbjct: 181 LHTL----TKHQEPVYSVAF-SPDGKYLASGSFDKCVHIWNVQTG 300
>20662
          Length = 1220

 Score = 44.3 bits (103), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 32/117 (27%), Positives = 55/117 (47%), Gaps = 2/117 (1%)
 Frame = +2

Query: 387 FTFSPHGGPVYSVSCSPFHRNLFLSAGTDGHVHLYSMLQAQPLTSL-QLSHKYL-FAVRW 444
           +T+  H   V+ V C P    LFLS   DG + L+ + +++P T L + S  +    V+W
Sbjct: 491 YTYRAHSDIVWDVQCHPTEPALFLSCSQDGKIVLWDVRESKPATCLPKCSSGFKPTCVQW 670

Query: 445 SPVRPLVFAAASGEGDVQLFDLQKSSQKPTVSITQTQDGSPVYCLEFNSQQTQLLAA 501
            P    ++A     G V + DL+   +K   +++       V  L F  Q+  +LA+
Sbjct: 671 QPNARNMYAVGDEGGHVSVQDLRMVVEK---NVSYQSHNRVVTRLAFCPQRPSMLAS 832
>08355
          Length = 498

 Score = 39.7 bits (91), Expect = 0.003,   Method: Composition-based stats.
 Identities = 40/190 (21%), Positives = 75/190 (39%), Gaps = 6/190 (3%)
 Frame = -1

Query: 238 LYSGEVLVWDMSRPEDPLLWRTGLTDDTHTDPVYQVLWLPEPRHSHRFQVLSAATDGKVL 297
            Y G V +++     +  + R    +  HTDPV+QV W  +   ++     S ++DG+++
Sbjct: 498 FYDGSVALFNTIEKHNNPVQRCTADNGKHTDPVWQVRWQKDDSDNN-MNFFSISSDGRIV 322

Query: 298 LWRGSGAGQLRLTKGFALAVQQLPRSTKLKKPPRGETEVGV------TSVAFSSFDSSLF 351
            W         + K   +  Q + + T    P  G   + +      T+  F      LF
Sbjct: 321 HW--------TIVKN-EMIYQDIIQLTIPGPPAEGPDGIRMEVTGCGTAFDFHKHKDYLF 169

Query: 352 VLGTEGGFPLKCSLASEVAALTRMPSSVPLRAPVQFTFSPHGGPVYSVSCSPFHRNLFLS 411
           ++GTE G    CS A     +               +   H   +Y V+ + FH N++ +
Sbjct: 168 LVGTEEGKMHVCSKAYTSHFIG--------------SGDAHNMAIYKVAWNRFHPNVYAT 31

Query: 412 AGTDGHVHLY 421
              D +V ++
Sbjct: 30  CSADWNVKIW 1
>02960
          Length = 1577

 Score = 37.4 bits (85), Expect = 0.016,   Method: Compositional matrix adjust.
 Identities = 60/259 (23%), Positives = 105/259 (40%), Gaps = 12/259 (4%)
 Frame = +2

Query: 266 HTDPVYQVLWLPEPRHSHRFQVLSAATDGKVLLW---RGSGAGQLRLT-KGFALAVQQLP 321
           HT PV  V W+     S     ++ + D   L+W   R +     RL+ +G A +V  + 
Sbjct: 599 HTSPVKCVAWIKHDESSGVSTFVTGSHDQTALVWQWQRETNEVDCRLSCRGHAASVDCVA 778

Query: 322 RSTKLKKPPRGETEVGVTSVAFSSFDSSLFVLGTEGGFPLKCSLASEVAALTRMP----- 376
            S   ++   G            S+D  L +  T+      C++  + +  T  P     
Sbjct: 779 VSPDSQQMCTG------------SWDKMLKLWSTD------CNVDGDQSEDTERPSKKKK 904

Query: 377 ---SSVPLRAPVQFTFSPHGGPVYSVSCSPFHRNLFLSAGTDGHVHLYSMLQAQPLTSLQ 433
              S+   R PV  T S H   V +V     HR   +++  D  + L+ +  AQ  TSL 
Sbjct: 905 SAKSTTQTRVPV-LTLSGHAEAVSAVRWLDPHR--VVTSSWDHSLRLWDLHTAQQ-TSLI 1072

Query: 434 LSHKYLFAVRWSPVRPLVFAAASGEGDVQLFDLQKSSQKPTVSITQTQDGSPVYCLEFNS 493
              K +  V +SP+  ++    S +  V+L D  + S+  TV    T     V  ++++ 
Sbjct: 1073QGSKAVLDVAYSPLSHMLI-TGSADRHVRLVD-PRCSEGETVKCAFTSHTGWVTGVDWSP 1246

Query: 494 QQTQLLAAGDAKGMVKVWQ 512
            +  L  +G    ++K+W 
Sbjct: 1247TREHLFLSGSYDNVLKLWD 1303
>00825
          Length = 1821

 Score = 37.0 bits (84), Expect = 0.018,   Method: Compositional matrix adjust.
 Identities = 25/93 (26%), Positives = 45/93 (48%)
 Frame = -2

Query: 378  SVPLRAPVQFTFSPHGGPVYSVSCSPFHRNLFLSAGTDGHVHLYSMLQAQPLTSLQLSHK 437
            S P+R     +FS     V+ V  +P    L  +A  D  + LY M  + PL  + +  +
Sbjct: 1517 SEPMR-----SFSWGVESVHHVKFNPVETYLLGAAAHDRSILLYDMRGSAPLRKVVMKMR 1353

Query: 438  YLFAVRWSPVRPLVFAAASGEGDVQLFDLQKSS 470
               A+ W+P+      +A+ +G++  FD++K S
Sbjct: 1352 -TNALSWNPMEAFTITSANEDGNLYTFDMRKLS 1257
>01598
          Length = 1545

 Score = 35.4 bits (80), Expect = 0.066,   Method: Compositional matrix adjust.
 Identities = 23/125 (18%), Positives = 52/125 (41%)
 Frame = +1

Query: 389 FSPHGGPVYSVSCSPFHRNLFLSAGTDGHVHLYSMLQAQPLTSLQLSHKYLFAVRWSPVR 448
           + PH  PV+++  S        +   D  V L+ +   + + S+     +++ VR SP+ 
Sbjct: 364 YRPHMRPVFNICASGPDSKTLCTFAQDRQVVLWDLETMEAVASMATLGGHVYCVRTSPID 543

Query: 449 PLVFAAASGEGDVQLFDLQKSSQKPTVSITQTQDGSPVYCLEFNSQQTQLLAAGDAKGMV 508
           P   A   G+  ++ +++   +    V+       S V  + ++  +   L  G   G +
Sbjct: 544 PGRVAVGVGDSMIRTWNMSNKTNPYDVTTLWQGIKSKVTAVAWHPTKEGWLGFGTDDGRI 723

Query: 509 KVWQL 513
            V+ +
Sbjct: 724 GVFDV 738
>37142
          Length = 327

 Score = 34.7 bits (78), Expect = 0.093,   Method: Compositional matrix adjust.
 Identities = 11/32 (34%), Positives = 22/32 (68%)
 Frame = +2

Query: 224 LAFHPTQPSHIAGGLYSGEVLVWDMSRPEDPL 255
           L F+P Q + +A G    E+ +WD+++P++P+
Sbjct: 122 LDFNPFQTNLLASGASESEIYIWDLNKPDNPM 217

 Score = 30.4 bits (67), Expect = 2.1,   Method: Compositional matrix adjust.
 Identities = 20/66 (30%), Positives = 32/66 (48%), Gaps = 2/66 (3%)
 Frame = +2

Query: 451 VFAAASGEGDVQLFDLQKS-SQKPTVSITQ-TQDGSPVYCLEFNSQQTQLLAAGDAKGMV 508
           V    +  G V ++  QK        S+ Q T+    V  L+FN  QT LLA+G ++  +
Sbjct: 2   VIVGGADNGSVLVYSAQKMIDGDADCSVLQLTKHTGAVKALDFNPFQTNLLASGASESEI 181

Query: 509 KVWQLS 514
            +W L+
Sbjct: 182 YIWDLN 199
>03387
          Length = 1891

 Score = 34.7 bits (78), Expect = 0.10,   Method: Compositional matrix adjust.
 Identities = 25/88 (28%), Positives = 43/88 (48%), Gaps = 1/88 (1%)
 Frame = +1

Query: 223 CLAFHPTQPSHIAGGLYSGEVLVWDMSRPEDPLLWRTGLTDDTHTDPVYQVLWLPEPRHS 282
           CL+F+P     +A G     V +WD+   +  L      + ++H D ++QV W P     
Sbjct: 664 CLSFNPYSEFILATGSADKTVALWDLRNLKLKL-----HSFESHKDEIFQVQWSP----- 813

Query: 283 HRFQVL-SAATDGKVLLWRGSGAGQLRL 309
           H   +L S+ TD ++ +W  S  G+ +L
Sbjct: 814 HNETILASSGTDRRLHVWDLSKIGEEQL 897

 Score = 33.1 bits (74), Expect = 0.31,   Method: Compositional matrix adjust.
 Identities = 26/124 (20%), Positives = 49/124 (39%), Gaps = 7/124 (5%)
 Frame = +1

Query: 397 YSVSCSPFHRNLFLSAGTDGHVHLYSMLQAQPLTSLQLSHKYLFA-------VRWSPVRP 449
           Y +S +P      LSA  D  + L+ +   Q  + +  +H            V W  +  
Sbjct: 373 YGLSWNPNLNGHLLSASDDHTICLWDINSTQRESRVVDAHTIFTGHTSVVEDVAWHLLHE 552

Query: 450 LVFAAASGEGDVQLFDLQKSSQKPTVSITQTQDGSPVYCLEFNSQQTQLLAAGDAKGMVK 509
            +F + + +  + ++D + ++      +      + V CL FN     +LA G A   V 
Sbjct: 553 SLFGSVADDQKLMIWDTRSNTTSKPSHVVDAH-TAEVNCLSFNPYSEFILATGSADKTVA 729

Query: 510 VWQL 513
           +W L
Sbjct: 730 LWDL 741
>01748
          Length = 998

 Score = 33.1 bits (74), Expect = 0.27,   Method: Compositional matrix adjust.
 Identities = 18/43 (41%), Positives = 23/43 (53%)
 Frame = +1

Query: 374 RMPSSVPLRAPVQFTFSPHGGPVYSVSCSPFHRNLFLSAGTDG 416
            M  + P+  P  F F PH   V S+S S  H N+F+SA T G
Sbjct: 154 EMAFNNPILTPKIFHFVPHTWKVSSLSXSHTHTNIFISAYTQG 282
>12780
          Length = 598

 Score = 31.6 bits (70), Expect = 0.91,   Method: Compositional matrix adjust.
 Identities = 19/58 (32%), Positives = 31/58 (53%), Gaps = 5/58 (8%)
 Frame = -3

Query: 365 LASEVAALTR--MPSSVPLRAPVQ---FTFSPHGGPVYSVSCSPFHRNLFLSAGTDGH 417
           + S V+   R  +P  +P  A V+   +T +P   PV  + C P H+N+ ++AG  GH
Sbjct: 239 IRSRVSQFVRHHLPWLIPTPAIVETCMYTNTPDNNPV--IDCLPKHKNIIVAAGFSGH 72
>04395
          Length = 1145

 Score = 31.2 bits (69), Expect = 0.97,   Method: Compositional matrix adjust.
 Identities = 39/170 (22%), Positives = 59/170 (34%), Gaps = 5/170 (2%)
 Frame = +3

Query: 222 MCLAFHPTQPSHIAGGLYSGEVLVWDMSRPEDPLLWRTGLTDDTHTDPVYQVLWLPEPRH 281
           +C+  HP Q   +A G   G + VWD+     P+         T  D  +  +W      
Sbjct: 486 LCVDKHPGQLHIVATGSQDGTLTVWDLRHHRFPM---------TTLDAHHSSMWEVRFHQ 638

Query: 282 SHRFQVLSAATDGKVLLWRGSGAGQLRLTKGFALAVQQLPRSTKLKKPPRGETEVGVTSV 341
            H   + + + DG +  W  S      L        QQ P    L+  P+ E    + + 
Sbjct: 639 QHTPHLFTCSEDGSLWHWDASAHAASLLKSAGGGEGQQSPW-LGLETSPKLEINSLICNK 815

Query: 342 AFSSFDSSLFVLGTEGGFPLKCSLASEVAALTRMP-----SSVPLRAPVQ 386
           +      S+  L  + G  L C   SE      +P     SSV    P Q
Sbjct: 816 SL-----SVNSLDVQAG-RLLCGTDSENIYTINLPQLA*SSSVSFSLPCQ 947
>19949
          Length = 903

 Score = 31.2 bits (69), Expect = 1.0,   Method: Compositional matrix adjust.
 Identities = 30/105 (28%), Positives = 53/105 (50%)
 Frame = +2

Query: 411 SAGTDGHVHLYSMLQAQPLTSLQLSHKYLFAVRWSPVRPLVFAAASGEGDVQLFDLQKSS 470
           S   D +V L+ + +   + + +     +  +R+SP    + A+AS +G V+L+DL  ++
Sbjct: 44  SGSMDCNVKLWDIRRKGCIYTYKGHTGCVCCLRFSPDGRWI-ASASEDGLVKLWDL--TA 214

Query: 471 QKPTVSITQTQDGSPVYCLEFNSQQTQLLAAGDAKGMVKVWQLST 515
            K    +   +D   V  +EF+  +  LLA+G A   VK W L T
Sbjct: 215 GKLLTDLKLHRDA--VNTIEFHPHEF-LLASGSADRTVKFWDLET 340
>13890
          Length = 630

 Score = 30.8 bits (68), Expect = 1.4,   Method: Compositional matrix adjust.
 Identities = 17/58 (29%), Positives = 30/58 (51%)
 Frame = +1

Query: 407 NLFLSAGTDGHVHLYSMLQAQPLTSLQLSHKYLFAVRWSPVRPLVFAAASGEGDVQLF 464
           ++  S  +DG +H YS    + + +L    + +  V   P+ P V AAA+ +GD+  F
Sbjct: 445 SIVYSGSSDGKLHCYSFNTTKKIRTLHCG-QVVMDVTSHPLLPSVVAAATWDGDLVFF 615
>07474
          Length = 365

 Score = 30.4 bits (67), Expect = 2.0,   Method: Composition-based stats.
 Identities = 15/37 (40%), Positives = 19/37 (51%)
 Frame = +1

Query: 380 PLRAPVQFTFSPHGGPVYSVSCSPFHRNLFLSAGTDG 416
           P+  P  F F PH   V  +S    H N+F+SA T G
Sbjct: 172 PILTPKIFHFVPHTWKVSFLSLCHTHTNIFISAYTQG 282
>23118
          Length = 651

 Score = 28.5 bits (62), Expect = 7.2,   Method: Compositional matrix adjust.
 Identities = 21/66 (31%), Positives = 30/66 (45%), Gaps = 1/66 (1%)
 Frame = +1

Query: 406 RNLFLSAG-TDGHVHLYSMLQAQPLTSLQLSHKYLFAVRWSPVRPLVFAAASGEGDVQLF 464
           R++ L  G  DG +  +S+   QP+ SL      L    WS    L+  A +G  D  +F
Sbjct: 82  RSVKLMVGQKDGIIRFFSLSNQQPIMSLSCGVSPLLDCDWSKHNCLLVGAVAG-ADWIVF 258

Query: 465 DLQKSS 470
           D   SS
Sbjct: 259 DTSVSS 276
>30295
          Length = 593

 Score = 28.1 bits (61), Expect = 8.9,   Method: Compositional matrix adjust.
 Identities = 14/44 (31%), Positives = 24/44 (54%)
 Frame = +2

Query: 258 RTGLTDDTHTDPVYQVLWLPEPRHSHRFQVLSAATDGKVLLWRG 301
           RT  T   H   +Y + W  + R+     ++SA+ DGK+++W G
Sbjct: 218 RTRRTLRXHLAKIYAMHWATDSRN-----LVSASQDGKLIVWDG 334
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|167234433|ref|NP_955760.3| echinoderm microtubule
associated protein like 4 3 [Mus musculus]
         (876 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

18461                                                                 112   9e-25
27525                                                                  81   2e-15
15972                                                                  45   1e-04
03387                                                                  43   7e-04
15780                                                                  38   0.015
13335                                                                  38   0.016
31384                                                                  37   0.027
12806                                                                  37   0.042
03044                                                                  36   0.071
19498                                                                  35   0.14 
19863                                                                  35   0.15 
00561                                                                  35   0.19 
27270                                                                  34   0.20 
12574                                                                  34   0.20 
17598                                                                  34   0.26 
25930                                                                  34   0.30 
02147                                                                  34   0.33 
29912                                                                  33   0.33 
01768                                                                  33   0.44 
14500                                                                  33   0.54 
10264                                                                  33   0.58 
02960                                                                  33   0.68 
26107                                                                  33   0.73 
01598                                                                  32   0.80 
30295                                                                  32   1.2  
20662                                                                  32   1.5  
19949                                                                  31   1.7  
03156                                                                  31   1.8  
06563                                                                  31   2.1  
01327                                                                  31   2.4  
01249                                                                  31   2.6  
05408                                                                  30   3.3  
12841                                                                  30   3.3  
34005                                                                  30   3.5  
03395                                                                  30   4.2  
27475                                                                  30   4.8  
04524                                                                  30   5.1  
27681                                                                  27   5.5  
01805                                                                  30   5.8  
>18461
          Length = 456

 Score =  112 bits (279), Expect = 9e-25,   Method: Compositional matrix adjust.
 Identities = 61/148 (41%), Positives = 90/148 (60%), Gaps = 1/148 (0%)
 Frame = +1

Query: 547 VAIGTHSGRWFVLDAETRDLVSIHTDGNEQLSVMRYSVD-GTLLAVGSHDNFIYLYTVLE 605
           +A+G   G + VL++ET + ++      E++S +++S D G  LAV SHDNF+ LY+V  
Sbjct: 7   LAVGLKDGSFVVLNSETLEEIAGFHHRKEEISDIKFSPDVGKYLAVASHDNFVDLYSVA- 183

Query: 606 NGRKYSRYGKCTGHSSYITHLDWSPDNKHIMSNSGDYEILYWDIENGCKLIRNRSDCKDI 665
            G K  R G C G SSYITH+DW    K +M NSG  E L+++   G ++    ++ +  
Sbjct: 184 -GVK--RVGTCKGASSYITHIDWDTRGKVLMVNSGAKEQLFFEAPRGKRITLRNTEIEKF 354

Query: 666 DWTTYTCVLGFQVFGVWPEGSDGTDINA 693
           +W ++TCVLG    GVWP  SD TD+NA
Sbjct: 355 NWASWTCVLGVTCEGVWPAKSDVTDVNA 438
>27525
          Length = 828

 Score = 81.3 bits (199), Expect = 2e-15,   Method: Compositional matrix adjust.
 Identities = 41/137 (29%), Positives = 83/137 (60%), Gaps = 2/137 (1%)
 Frame = +2

Query: 560 DAETRDLVSIHTDGNEQLSVMRYSVDGTLLAVGSHDNFIYLYTVLENGRKYSRYGKCTGH 619
           D + R+  +    G  Q++ + +S DG+ LAVG HD F+++Y V E+G  + +      +
Sbjct: 26  DMDGREPRNSFQVGQAQINAISFSPDGSQLAVGCHDGFVHVYVVHEDGLVFRQKSAALRY 205

Query: 620 -SSYITHLDWSPDNKHIMSNSGDYEILYWDIENGCKLIRNRSDCKDIDWTTYTCVLGF-Q 677
            S++I HLDWS D +++    GDYE+++W+++N  K  ++    +D++W+T++  +G+  
Sbjct: 206 NSTFIMHLDWSSDCRYLQCTLGDYELVFWEVQNMKK--QSGRALRDVNWSTFSSPVGYPP 379

Query: 678 VFGVWPEGSDGTDINAL 694
            + +  +G+ G+D + L
Sbjct: 380 CWALADDGARGSDQHGL 430

 Score = 50.4 bits (119), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 25/94 (26%), Positives = 46/94 (48%)
 Frame = +3

Query: 673 VLGFQVFGVWPEGSDGTDINALVRSHNRRVIAVADDFCKVHLFQYPCSKAKAPSHKYSAH 732
           +L   + G W     G  IN   RS     I   D   ++ LF+YP + +K    +   +
Sbjct: 363 LLDTPLVGPWQMMERGEVINMACRSKYLDFILTGDSRGRIRLFKYPSTGSKVECQETKPY 542

Query: 733 SSHVTNVSFTHNDSHLISTGGKDMSIIQWKLVEK 766
           SS+ T      +DS ++ +GG+D +++ + LV++
Sbjct: 543 SSNTTAAEILSDDSGILVSGGRDAALMYFALVDR 644
>15972
          Length = 1069

 Score = 45.4 bits (106), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 33/128 (25%), Positives = 60/128 (46%), Gaps = 9/128 (7%)
 Frame = +3

Query: 489 GHTDELWGLATHPFKDLLLTCAQDRQVCMWNSVEHRLEWTRLVDEPGHCADFHPSGT--V 546
           GH   +  LA HP   L LT +QDR + +WN++  R+ +   + E      + P G   V
Sbjct: 231 GHKGPVRHLAVHPSGKLTLTVSQDRTLRLWNNMNGRIAFISNMKEAAESVRWAPGGLYYV 410

Query: 547 VAIGTHSGRWFVLDAETRDLV-------SIHTDGNEQLSVMRYSVDGTLLAVGSHDNFIY 599
           VA  +H     V   E++ L+       ++++ G    +V+ Y  +G ++  G  ++   
Sbjct: 411 VAFRSH---LDVYSVESKGLLRSIDTSQTVNSVGFVTDTVLVYGGEGKVMKNGEREHASL 581

Query: 600 LYTVLENG 607
            +T + NG
Sbjct: 582 FFTDILNG 605
>03387
          Length = 1891

 Score = 42.7 bits (99), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 48/178 (26%), Positives = 76/178 (42%), Gaps = 7/178 (3%)
 Frame = +1

Query: 593 SHDNFIYLYTVLENGRKYSRYGKC------TGHSSYITHLDWSPD-NKHIMSNSGDYEIL 645
           S D  ++ YT  ++  K    G+C       GH      L W+P+ N H++S S D+ I 
Sbjct: 268 SSDVLVFDYT--KHPSKPDPSGECIPELRLKGHQKEGYGLSWNPNLNGHLLSASDDHTIC 441

Query: 646 YWDIENGCKLIRNRSDCKDIDWTTYTCVLGFQVFGVWPEGSDGTDINALVRSHNRRVIAV 705
            WDI N  +      D   I +T +T V+               D+ A    H     +V
Sbjct: 442 LWDI-NSTQRESRVVDAHTI-FTGHTSVV--------------EDV-AWHLLHESLFGSV 570

Query: 706 ADDFCKVHLFQYPCSKAKAPSHKYSAHSSHVTNVSFTHNDSHLISTGGKDMSIIQWKL 763
           ADD  K+ ++    +    PSH   AH++ V  +SF      +++TG  D ++  W L
Sbjct: 571 ADD-QKLMIWDTRSNTTSKPSHVVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDL 741
>15780
          Length = 735

 Score = 38.1 bits (87), Expect = 0.015,   Method: Compositional matrix adjust.
 Identities = 19/47 (40%), Positives = 25/47 (53%)
 Frame = -1

Query: 403 QIKAHDGSVFTLCQMRNGMLLTGGGKDRKIILWDHDLNLEREIEVPD 449
            + AH  +V+ LC  R+G +L  GG D  I LWD    L R +E  D
Sbjct: 663 HLTAHTDTVYALCFSRDGTVLASGGMDNSIRLWD----LARVMEEQD 535
>13335
          Length = 863

 Score = 38.1 bits (87), Expect = 0.016,   Method: Compositional matrix adjust.
 Identities = 52/233 (22%), Positives = 81/233 (34%), Gaps = 25/233 (10%)
 Frame = +1

Query: 399 QINRQIKAHDGSVFTLCQMRNGMLLTGGGKDRKIILWD---------------HDLNLER 443
           ++ R    H+ SV  L    NG  L  G  +  + +WD               HDL +  
Sbjct: 160 KLVRSYVGHEDSVMALAYSPNGHYLVSGSPNGDLYVWDASFGHCRHLTLRVDAHDLGVTC 339

Query: 444 EIEVPDQYGTIRAVAEGRAEQFLV-GTSRNFILRGTFNDGF---QIEVQ------GHTDE 493
             E    +GT  A         L  G   N I   TF+      ++ +Q      GH+D 
Sbjct: 340 -CEFSPTFGTACAENSSTCNLLLATGGKDNLIKLWTFSAQVGSPEVTLQCRDILSGHSDL 516

Query: 494 LWGLATHPFKDLLLTCAQDRQVCMWNSVEHRLEWTRLVDEPGHCADFHPSGTVVAIGTHS 553
           +   A  P   LL + + D+ V +W+SV+                     G         
Sbjct: 517 VMACAFSPSSALLASGSFDKSVRLWDSVK---------------------GVA------- 612

Query: 554 GRWFVLDAETRDLVSIHTDGNEQLSVMRYSVDGTLLAVGSHDNFIYLYTVLEN 606
                       L SI    +  ++   +S+DGTLLA GS D  I ++ + + 
Sbjct: 613 ------------LFSIEACHSRFVTCCAFSIDGTLLASGSMDRIIKIWKLTDT 735

 Score = 36.6 bits (83), Expect = 0.041,   Method: Compositional matrix adjust.
 Identities = 42/177 (23%), Positives = 67/177 (37%), Gaps = 21/177 (11%)
 Frame = +1

Query: 501 PFKDLLLTCAQDRQVCMWNSVEHRLEWTRLVDEPGHCA-DFHPSGTVVAIGTHSGRWFVL 559
           P    L++ + D  +CMW     +L  + +  E    A  + P+G  +  G+ +G  +V 
Sbjct: 91  PSSSHLVSGSDDDTICMWEVATQKLVRSYVGHEDSVMALAYSPNGHYLVSGSPNGDLYVW 270

Query: 560 DAE---TRDLVSIHTDGNE-------------QLSVMRYSVDGTLLAVGSHDNFIYLYTV 603
           DA     R L ++  D ++                    S    LLA G  DN I L+T 
Sbjct: 271 DASFGHCRHL-TLRVDAHDLGVTCCEFSPTFGTACAENSSTCNLLLATGGKDNLIKLWTF 447

Query: 604 LENGRKYSRYGKC----TGHSSYITHLDWSPDNKHIMSNSGDYEILYWDIENGCKLI 656
                      +C    +GHS  +    +SP +  + S S D  +  WD   G  L 
Sbjct: 448 SAQVGSPEVTLQCRDILSGHSDLVMACAFSPSSALLASGSFDKSVRLWDSVKGVALF 618

 Score = 35.0 bits (79), Expect = 0.14,   Method: Compositional matrix adjust.
 Identities = 48/214 (22%), Positives = 85/214 (39%), Gaps = 6/214 (2%)
 Frame = +1

Query: 574 NEQLSVMRYSVDGTLLAVGSHDNFIYLYTVLENG--RKYSRYGKCTGHSSYITHLDWSPD 631
              + V ++S   + L  GS D+ I ++ V      R Y       GH   +  L +SP+
Sbjct: 61  KSSIRVCKFSPSSSHLVSGSDDDTICMWEVATQKLVRSY------VGHEDSVMALAYSPN 222

Query: 632 NKHIMSNSGDYEILYWDIENG-CKLIRNRSDCKDIDWTTYTCVLGFQVFGVWPEGSDGTD 690
             +++S S + ++  WD   G C+ +  R D  D+     TC      FG      + + 
Sbjct: 223 GHYLVSGSPNGDLYVWDASFGHCRHLTLRVDAHDLG---VTCCEFSPTFGT-ACAENSST 390

Query: 691 INALVRSHNRRVIAVADDFCKVHLFQYPCSKAKAPSHK---YSAHSSHVTNVSFTHNDSH 747
            N L+ +  +      D+  K+  F       +         S HS  V   +F+ + S 
Sbjct: 391 CNLLLATGGK------DNLIKLWTFSAQVGSPEVTLQCRDILSGHSDLVMACAFSPS-SA 549

Query: 748 LISTGGKDMSIIQWKLVEKLPVPQNEVITDASVT 781
           L+++G  D S+  W  V+ + +   E      VT
Sbjct: 550 LLASGSFDKSVRLWDSVKGVALFSIEACHSRFVT 651

 Score = 34.3 bits (77), Expect = 0.21,   Method: Compositional matrix adjust.
 Identities = 43/206 (20%), Positives = 82/206 (39%), Gaps = 19/206 (9%)
 Frame = +1

Query: 198 ERTQRHYLGHTDCVRCLAVHPDKIRIATGQIAGVDKDGRPLQPHVRVWDSVSLTTLHV-I 256
           ++  R Y+GH D V  LA  P+   + +G   G           + VWD+      H+ +
Sbjct: 157 QKLVRSYVGHEDSVMALAYSPNGHYLVSGSPNG----------DLYVWDASFGHCRHLTL 306

Query: 257 GLGTFERGVGCLDFS--------KADSGVHLCVIDDSNEHMLTVWDWQKKSKIAEIKTT- 307
            +   + GV C +FS        +  S  +L +     ++++ +W +  +    E+    
Sbjct: 307 RVDAHDLGVTCCEFSPTFGTACAENSSTCNLLLATGGKDNLIKLWTFSAQVGSPEVTLQC 486

Query: 308 -------NEVVLAVEFHPTDANTIITCGKSHIFFW-TWSGNSLTRKQGIFGKYEKPKFVQ 359
                  +++V+A  F P+ A          +  W +  G +L   +         +FV 
Sbjct: 487 RDILSGHSDLVMACAFSPSSALLASGSFDKSVRLWDSVKGVALFSIEAC-----HSRFVT 651

Query: 360 CLAFLGNGDVL-TGDSGGVMLIWSKT 384
           C AF  +G +L +G    ++ IW  T
Sbjct: 652 CCAFSIDGTLLASGSMDRIIKIWKLT 729
>31384
          Length = 474

 Score = 37.4 bits (85), Expect = 0.027,   Method: Compositional matrix adjust.
 Identities = 22/92 (23%), Positives = 44/92 (47%), Gaps = 4/92 (4%)
 Frame = -1

Query: 569 IHTDGNEQLSVMRYS---VDGTLLAVGSHDNFIYLYTVLENGRKYSRYGKCTGHSSYITH 625
           + +  ++ +S +++S   +  T L  GS DN +  + V ++G+   +  +   H+  +  
Sbjct: 291 VTSPPDDSVSCLKFSPGALPSTFLISGSWDNKVSCWEVQQSGQTIPKAQQ--THTGPVLD 118

Query: 626 LDWSPDNKHIMSNSGDYEILYWDIE-NGCKLI 656
           +DWS D   + + S D     WD+  N C  I
Sbjct: 117 VDWSDDGTKVFTASCDKTAKVWDLNSNQCMQI 22
>12806
          Length = 961

 Score = 36.6 bits (83), Expect = 0.042,   Method: Compositional matrix adjust.
 Identities = 29/100 (29%), Positives = 49/100 (49%), Gaps = 12/100 (12%)
 Frame = +3

Query: 578 SVMRYS---VDGT---LLAVGSHDNFIYLYTV--LENGRKYSRYG----KCTGHSSYITH 625
           + M+Y    VDG     L  G  DN I ++ +   ++G +   +G      TGHS +I+ 
Sbjct: 3   TTMQYGEQVVDGATKPFLISGGRDNNIIVWDL*PKKDGDEDQTWGVPRKTLTGHSHFISD 182

Query: 626 LDWSPDNKHIMSNSGDYEILYWDIENGCKLIRNRSDCKDI 665
           L  S D++  +S+S D  +  WDI+ G    R  +  +D+
Sbjct: 183 LALSADSRFALSSSWDATLRLWDIKKGSTTSRFINHTRDV 302

 Score = 32.3 bits (72), Expect = 0.78,   Method: Compositional matrix adjust.
 Identities = 44/189 (23%), Positives = 74/189 (39%)
 Frame = +3

Query: 577 LSVMRYSVDGTLLAVGSHDNFIYLYTVLENGRKYSRYGKCTGHSSYITHLDWSPDNKHIM 636
           +S +  S D       S D  + L+ + + G   SR+     H+  +  + +SPDN+ I 
Sbjct: 174 ISDLALSADSRFALSSSWDATLRLWDI-KKGSTTSRF---INHTRDVLTVAFSPDNRQIA 341

Query: 637 SNSGDYEILYWDIENGCKLIRNRSDCKDIDWTTYTCVLGFQVFGVWPEGSDGTDINALVR 696
           S   D  +  W+I   CK   + +     DW   TCV   Q           T    +V 
Sbjct: 342 SGGRDKNLKIWNIMGECKYTVDAN--AHTDWV--TCVRFHQ----------DTKNPIVVS 479

Query: 697 SHNRRVIAVADDFCKVHLFQYPCSKAKAPSHKYSAHSSHVTNVSFTHNDSHLISTGGKDM 756
           + N + I V D+    H             + +  H + +T +  + N  +L+S G KD 
Sbjct: 480 ASNDKTIKVWDN----HTMTL--------KNTFVGHKAQITALDMSTN--YLVS-GSKDG 614

Query: 757 SIIQWKLVE 765
             + W + E
Sbjct: 615 IAMTWNVAE 641

 Score = 30.8 bits (68), Expect = 2.8,   Method: Compositional matrix adjust.
 Identities = 47/206 (22%), Positives = 78/206 (37%), Gaps = 22/206 (10%)
 Frame = +3

Query: 422 LLTGGGKDRKIILWD----HDLNLEREIEVPDQYGT-----IRAVAEGRAEQFLVGTSRN 472
            L  GG+D  II+WD     D + ++   VP +  T     I  +A     +F + +S +
Sbjct: 51  FLISGGRDNNIIVWDL*PKKDGDEDQTWGVPRKTLTGHSHFISDLALSADSRFALSSSWD 230

Query: 473 FILR------GTFNDGFQIEVQGHTDELWGLATHPFKDLLLTCAQDRQVCMWNSVEHRLE 526
             LR      G+    F      HT ++  +A  P    + +  +D+ + +WN +    E
Sbjct: 231 ATLRLWDIKKGSTTSRF----INHTRDVLTVAFSPDNRQIASGGRDKNLKIWNIMG---E 389

Query: 527 WTRLVDEPGH-----CADFH--PSGTVVAIGTHSGRWFVLDAETRDLVSIHTDGNEQLSV 579
               VD   H     C  FH      +V   ++     V D  T  L +       Q++ 
Sbjct: 390 CKYTVDANAHTDWVTCVRFHQDTKNPIVVSASNDKTIKVWDNHTMTLKNTFVGHKAQITA 569

Query: 580 MRYSVDGTLLAVGSHDNFIYLYTVLE 605
           +  S +   L  GS D     + V E
Sbjct: 570 LDMSTN--YLVSGSKDGIAMTWNVAE 641
>03044
          Length = 1952

 Score = 35.8 bits (81), Expect = 0.071,   Method: Compositional matrix adjust.
 Identities = 21/90 (23%), Positives = 42/90 (46%)
 Frame = -2

Query: 563  TRDLVSIHTDGNEQLSVMRYSVDGTLLAVGSHDNFIYLYTVLENGRKYSRYGKCTGHSSY 622
            T ++   H+ G + ++    S D   LA+  +D+ + +Y   +NG K+        H   
Sbjct: 1819 TGNMAEKHSFGVKAVTCHAASGDRNGLALSLNDHEVKIYK--KNGSKWQETDTLGEHGQR 1646

Query: 623  ITHLDWSPDNKHIMSNSGDYEILYWDIENG 652
            +T +DW+P +  I++   D     W  ++G
Sbjct: 1645 VTGIDWAPKSNRIVTCGADRNAYVWTYQDG 1556
>19498
          Length = 903

 Score = 35.0 bits (79), Expect = 0.14,   Method: Compositional matrix adjust.
 Identities = 23/88 (26%), Positives = 39/88 (44%), Gaps = 16/88 (18%)
 Frame = -1

Query: 577 LSVMRYSVDGTLLAVGSHDNFIYLY----------------TVLENGRKYSRYGKCTGHS 620
           ++ +R+S +G  LA G  D  I ++                T+LE+ R  +      GH+
Sbjct: 777 VNCVRWSENGKFLASGGDDKLIMIWQISRGFGSGKSFGSNVTILEHWRSVATL---RGHA 607

Query: 621 SYITHLDWSPDNKHIMSNSGDYEILYWD 648
             +  L WSP +  + S S D  I+ W+
Sbjct: 606 GDVLDLAWSPQDLWLASCSVDNTIVVWN 523
>19863
          Length = 502

 Score = 35.0 bits (79), Expect = 0.15,   Method: Compositional matrix adjust.
 Identities = 22/66 (33%), Positives = 34/66 (51%)
 Frame = +1

Query: 585 DGTLLAVGSHDNFIYLYTVLENGRKYSRYGKCTGHSSYITHLDWSPDNKHIMSNSGDYEI 644
           DG  L  GS D  I ++ V ENG +  R     GH+ ++  + +S D   ++S S D  +
Sbjct: 4   DGLQLVSGSSDMSIVVWDV-ENGVQKLRL---QGHAGWVNDVHFSQDQCWLLSCSNDNTV 171

Query: 645 LYWDIE 650
             W+IE
Sbjct: 172 RIWNIE 189
>00561
          Length = 1003

 Score = 34.7 bits (78), Expect = 0.19,   Method: Compositional matrix adjust.
 Identities = 49/252 (19%), Positives = 105/252 (41%), Gaps = 20/252 (7%)
 Frame = -3

Query: 423 LTGGGKDRKIILWDHDLNLEREIEVPDQ--YGTIRAVAEGRAEQFLVGTSRNFILRGTFN 480
           +    +D+ +I+W    + +     P +  YG    +++      ++ +  N+ L G+++
Sbjct: 965 IISASRDKTLIVWKLTRDEDTNYGYPQKRLYGHSHFISD-----VVLSSDGNYALSGSWD 801

Query: 481 DGFQI----------EVQGHTDELWGLATHPFKDLLLTCAQDRQVCMWNSVEHRLEWTRL 530
              ++            +GHT ++  +A       +++ ++D+ + +WN++    E    
Sbjct: 800 QTLRLWDLAAGKTTRRFEGHTKDVLSVAFSADNRQIVSGSRDKTIKLWNTLA---ECKFT 630

Query: 531 VDEPGH-----CADFHPSGT---VVAIGTHSGRWFVLDAETRDLVSIHTDGNEQLSVMRY 582
           + E GH     C  F P+ +   +V+ G       V +     L + H   N  L+ +  
Sbjct: 629 IQEDGHTDWVSCVRFSPNHSNPIIVSCGWDRTV-KVWNLANCKLKNNHHGHNGYLNTVTV 453

Query: 583 SVDGTLLAVGSHDNFIYLYTVLENGRKYSRYGKCTGHSSYITHLDWSPDNKHIMSNSGDY 642
           S DG+L   G  D+   L+ + +    Y+       H+  I  L +SP N++ +  +   
Sbjct: 452 SPDGSLCTSGGKDSKALLWDLNDGKNLYT-----LEHNDIINALCFSP-NRYWLCVAYGP 291

Query: 643 EILYWDIENGCK 654
            I  WD+   CK
Sbjct: 290 SIKIWDL--ACK 261

 Score = 32.0 bits (71), Expect = 0.98,   Method: Compositional matrix adjust.
 Identities = 14/31 (45%), Positives = 19/31 (61%)
 Frame = -3

Query: 406 AHDGSVFTLCQMRNGMLLTGGGKDRKIILWD 436
            H+G + T+    +G L T GGKD K +LWD
Sbjct: 485 GHNGYLNTVTVSPDGSLCTSGGKDSKALLWD 393
>27270
          Length = 1078

 Score = 34.3 bits (77), Expect = 0.20,   Method: Compositional matrix adjust.
 Identities = 21/67 (31%), Positives = 35/67 (52%)
 Frame = +2

Query: 583 SVDGTLLAVGSHDNFIYLYTVLENGRKYSRYGKCTGHSSYITHLDWSPDNKHIMSNSGDY 642
           + D  ++AVGS D  + LY+V E         K  GHS  +T + W  D + + S+S D 
Sbjct: 170 AADSAVVAVGSADGSVGLYSV-ETHTYTHMLNK--GHSKAVTDMCWRADGRTLYSSSLDG 340

Query: 643 EILYWDI 649
            ++ W++
Sbjct: 341 HVIGWNV 361
>12574
          Length = 521

 Score = 34.3 bits (77), Expect = 0.20,   Method: Composition-based stats.
 Identities = 21/76 (27%), Positives = 37/76 (48%)
 Frame = +3

Query: 577 LSVMRYSVDGTLLAVGSHDNFIYLYTVLENGRKYSRYGKCTGHSSYITHLDWSPDNKHIM 636
           LS +++S +G  LA  S D  I ++   +   K+ +     GH   ++ + WS D+K + 
Sbjct: 195 LSAVKFSPNGDWLASSSADKLIKIWGAYDG--KFEK--TIAGHKLGLSDVAWSSDSKLLC 362

Query: 637 SNSGDYEILYWDIENG 652
           S S D  +  W+   G
Sbjct: 363 SASDDKTLKIWEFSTG 410
>17598
          Length = 875

 Score = 33.9 bits (76), Expect = 0.26,   Method: Compositional matrix adjust.
 Identities = 52/260 (20%), Positives = 99/260 (38%), Gaps = 18/260 (6%)
 Frame = +1

Query: 422 LLTGGGKDRKIILWDHDLNLEREIEVPDQYGTIRAVAEGR----AEQFLVGTSRNFILRG 477
            L  GG+D+ +I+W  DL   ++ +  + +G  R   +G     ++  L   SR ++L  
Sbjct: 7   FLIXGGRDKLLIVW--DLVPRKDGDEDETWGGPRRTLQGHSHFVSDVSLSADSR-YVLSS 177

Query: 478 TFNDGFQI----------EVQGHTDELWGLATHPFKDLLLTCAQDRQVCMWNSVEHRLEW 527
           +++   ++              HT +   +A  P    + +  +D+ + +WN+V      
Sbjct: 178 SWDATLRLWDIKKGNTTRRFISHTRDALAVAFSPDNRQIASGGRDKALKIWNTV------ 339

Query: 528 TRLVDEPGHCADFHPSGTVVAIGTHSGRWFVLDAETRD----LVSIHTDGNEQLSVMRYS 583
                  G C                   F +DA +       V  H D    L V+  S
Sbjct: 340 -------GECK------------------FTVDANSHQDWVTCVKFHQDAKSPL-VVSAS 441

Query: 584 VDGTLLAVGSHDNFIYLYTVLENGRKYSRYGKCTGHSSYITHLDWSPDNKHIMSNSGDYE 643
           +D T + V  +      +T +             GH + I  +D +    ++ S S D  
Sbjct: 442 MDKT-IKVWDNQTMTLKHTFV-------------GHKTQINAIDLALKTYYLASGSKDGI 579

Query: 644 ILYWDIENGCKLIRNRSDCK 663
           ++ W+I+NG  L +   DC+
Sbjct: 580 VMTWNIQNGTFLGKIDCDCE 639

 Score = 33.5 bits (75), Expect = 0.43,   Method: Compositional matrix adjust.
 Identities = 20/83 (24%), Positives = 42/83 (50%), Gaps = 6/83 (7%)
 Frame = +1

Query: 588 LLAVGSHDNFIYLYTVL--ENGRKYSRYG----KCTGHSSYITHLDWSPDNKHIMSNSGD 641
            L  G  D  + ++ ++  ++G +   +G       GHS +++ +  S D+++++S+S D
Sbjct: 7   FLIXGGRDKLLIVWDLVPRKDGDEDETWGGPRRTLQGHSHFVSDVSLSADSRYVLSSSWD 186

Query: 642 YEILYWDIENGCKLIRNRSDCKD 664
             +  WDI+ G    R  S  +D
Sbjct: 187 ATLRLWDIKKGNTTRRFISHTRD 255
>25930
          Length = 419

 Score = 33.9 bits (76), Expect = 0.30,   Method: Compositional matrix adjust.
 Identities = 19/63 (30%), Positives = 29/63 (46%)
 Frame = +1

Query: 588 LLAVGSHDNFIYLYTVLENGRKYSRYGKCTGHSSYITHLDWSPDNKHIMSNSGDYEILYW 647
            +AVGS    I +Y V     + +R     G    I +L+WS D   ++S S    +  W
Sbjct: 100 FVAVGSVRGDILIYDVRLEPWRLARIAPSNGQDDSIKNLNWSLDATRLISVSESGTLQVW 279

Query: 648 DIE 650
           D+E
Sbjct: 280 DLE 288
>02147
          Length = 1547

 Score = 33.9 bits (76), Expect = 0.33,   Method: Compositional matrix adjust.
 Identities = 43/196 (21%), Positives = 81/196 (41%), Gaps = 15/196 (7%)
 Frame = +2

Query: 582 YSVDGTLLAVGSHDNFIYLYTVLENGRKYSRYGKCTGHSSYITHLDWSPDNKHIMSNSGD 641
           +S DGT L  GS++  + ++ ++    +   +    GH+S I    +  D K I+S S D
Sbjct: 320 FSHDGTALLTGSNEKLLKVFDLVNTDAEPKSFA---GHTSNIKGALFLSDGKRIISASDD 490

Query: 642 YEILYWDIENGCKLIRN-----------RSDCKDIDWTTYTCVLGFQVFGVWPE----GS 686
             +  W +E  C+ ++             S  K+    T++  + F       E     +
Sbjct: 491 KTVRLWSLET-CQEVQQLTFDTPPTSLTLSPDKNTIIVTHSQNIAFYQADTLREMKKFEA 667

Query: 687 DGTDINALVRSHNRRVIAVADDFCKVHLFQYPCSKAKAPSHKYSAHSSHVTNVSFTHNDS 746
           +    +A +    R  +A  +DF K++ F Y   K       +  H   V  V F+  D 
Sbjct: 668 EAPISSASLHQSERFFVAGGEDF-KMYKFDYETGK---EIESFKGHFGPVHCVRFS-PDG 832

Query: 747 HLISTGGKDMSIIQWK 762
            L ++G +D ++  W+
Sbjct: 833 ELYASGSEDGTLRLWQ 880
>29912
          Length = 510

 Score = 33.5 bits (75), Expect = 0.33,   Method: Compositional matrix adjust.
 Identities = 27/107 (25%), Positives = 45/107 (42%)
 Frame = +3

Query: 544 GTVVAIGTHSGRWFVLDAETRDLVSIHTDGNEQLSVMRYSVDGTLLAVGSHDNFIYLYTV 603
           G  +A+GT +G   V D   +    + T       V   S +  +++ GS    I+ + V
Sbjct: 45  GNYLALGTSTGEVQVWDVTQQK--KLRTMAGHAARVGSLSWNSFIVSSGSRSGNIHHHDV 218

Query: 604 LENGRKYSRYGKCTGHSSYITHLDWSPDNKHIMSNSGDYEILYWDIE 650
                     G  +GHS  +  L WSPD K++ S + D  +  W  +
Sbjct: 219 RVADH---HVGTLSGHSQEVCGLRWSPDGKYLASGANDNLLCVWPAQ 350
>01768
          Length = 1424

 Score = 33.1 bits (74), Expect = 0.44,   Method: Compositional matrix adjust.
 Identities = 24/91 (26%), Positives = 43/91 (47%), Gaps = 1/91 (1%)
 Frame = +3

Query: 570 HTDGNEQLSVMRYSVDGTLLAVGSHDNFIYLYTVLENGRKYSRYGKCTGHSSYITHLDWS 629
           HTD  E   V     +G + A  S D  + ++   +   K +       HS  I  ++W+
Sbjct: 834 HTDSVE--DVQWSPNEGNVFASCSVDRTLRIWNTQQKPSKANVLTVPEAHSRDINVINWN 1007

Query: 630 PDNKHIMSNSGDYEIL-YWDIENGCKLIRNR 659
           P  KH++++ GD  I+  WD+    ++ RN+
Sbjct: 1008PIEKHLLASGGDDGIIKIWDL----RMFRNK 1088
>14500
          Length = 1238

 Score = 33.1 bits (74), Expect = 0.54,   Method: Composition-based stats.
 Identities = 13/34 (38%), Positives = 19/34 (55%)
 Frame = +2

Query: 614 GKCTGHSSYITHLDWSPDNKHIMSNSGDYEILYW 647
           G  +GHS  +  L WSPD K++ S + D  +  W
Sbjct: 41  GTLSGHSQEVCGLRWSPDGKYLASGANDNLLCVW 142

 Score = 32.0 bits (71), Expect = 0.99,   Method: Compositional matrix adjust.
 Identities = 20/86 (23%), Positives = 34/86 (39%)
 Frame = +3

Query: 562 ETRDLVSIHTDGNEQLSVMRYSVDGTLLAVGSHDNFIYLYTVLENGRKYSRYGKCTGHSS 621
           E R+L+S H     QL + +Y                            SR  + TGH++
Sbjct: 366 EHRELISSHGFAQNQLIIWKYPA-------------------------MSRVAELTGHTA 470

Query: 622 YITHLDWSPDNKHIMSNSGDYEILYW 647
            + H+  SPD + ++S + D  +  W
Sbjct: 471 RVLHMAMSPDGETVVSAAADETLRLW 548
>10264
          Length = 416

 Score = 32.7 bits (73), Expect = 0.58,   Method: Compositional matrix adjust.
 Identities = 14/46 (30%), Positives = 25/46 (54%), Gaps = 1/46 (2%)
 Frame = -1

Query: 615 KCTGHSSYITHLDWSP-DNKHIMSNSGDYEILYWDIENGCKLIRNR 659
           + +GHS  +T + WSP  +  ++S   D E   WD++ G  L + +
Sbjct: 260 ELSGHSQRVTDMSWSPHHDARLVSVGYDAEAFVWDVQKGTALAQFK 123

 Score = 30.4 bits (67), Expect = 3.2,   Method: Compositional matrix adjust.
 Identities = 17/69 (24%), Positives = 33/69 (47%)
 Frame = -1

Query: 698 HNRRVIAVADDFCKVHLFQYPCSKAKAPSHKYSAHSSHVTNVSFTHNDSHLISTGGKDMS 757
           H+ R+++V  D      F +   K  A + ++  H   +    F+  D  L+ TGG D S
Sbjct: 209 HDARLVSVGYD---AEAFVWDVQKGTALA-QFKGHMGRLLTCQFSGLDPDLVMTGGSDAS 42

Query: 758 IIQWKLVEK 766
           +  W++ ++
Sbjct: 41  VHVWRVSQQ 15
>02960
          Length = 1577

 Score = 32.7 bits (73), Expect = 0.68,   Method: Compositional matrix adjust.
 Identities = 31/114 (27%), Positives = 52/114 (45%), Gaps = 4/114 (3%)
 Frame = +2

Query: 542  PSGTVVAIGTHSGR-WFVLDAETRDLVSIHTDGNEQLSVMRYSVDGTLLAVGSHDNFIYL 600
            P   V +   HS R W +  A+   L+     G++ +  + YS    +L  GS D  + L
Sbjct: 992  PHRVVTSSWDHSLRLWDLHTAQQTSLIQ----GSKAVLDVAYSPLSHMLITGSADRHVRL 1159

Query: 601  YTVLENGRKYSRYGKC--TGHSSYITHLDWSPDNKHI-MSNSGDYEILYWDIEN 651
               ++         KC  T H+ ++T +DWSP  +H+ +S S D  +  WD  +
Sbjct: 1160 ---VDPRCSEGETVKCAFTSHTGWVTGVDWSPTREHLFLSGSYDNVLKLWDTRS 1312
>26107
          Length = 1338

 Score = 32.7 bits (73), Expect = 0.73,   Method: Compositional matrix adjust.
 Identities = 27/94 (28%), Positives = 42/94 (44%), Gaps = 7/94 (7%)
 Frame = -3

Query: 589 LAVGSHDNFIYLYTVLENGRKYSRYGKCTGH--SSYITHLDWSPDNKHIMSNSGDYEILY 646
           L V   DN +Y Y +    R+   Y    GH   ++      SPD K+++S SG    + 
Sbjct: 520 LFVSYTDNKVYRYQLAGQYREPQEYVY-AGHRNDTFFVRCAISPDGKYLLSGSGRNTGVI 344

Query: 647 WDIENGCK----LIRNRSDCKDIDW-TTYTCVLG 675
           W+++   K    LI +  D   +DW +T  C L 
Sbjct: 343 WEVDKPNKRPLFLIGHTEDVSAVDWCSTDVCKLA 242
>01598
          Length = 1545

 Score = 32.3 bits (72), Expect = 0.80,   Method: Compositional matrix adjust.
 Identities = 29/140 (20%), Positives = 57/140 (40%), Gaps = 22/140 (15%)
 Frame = +1

Query: 540  FHPSGTVVAIGTHSGRWFVLDAETRDLVSIHTDGNEQLSVMRY-------SVDGT----L 588
            + P     A+GT  G  +V+  +   +V+      + ++ +R+       S  G+     
Sbjct: 997  WSPDQNAAAVGTDEGSVYVVTIQDLKIVAAIRTQQKLINCVRWHPRLTDQSPAGSPCCHW 1176

Query: 589  LAVGSHDNFIYLYTVL----------ENGRKYSRYGKCTGHSSYITHLDWSP-DNKHIMS 637
            LA   +D  I++  +           E     +   + +GHS  +T + WSP  +  ++S
Sbjct: 1177 LAAAGNDQVIHVVDLASVFAEREGDKETSLILTSLRELSGHSQRVTDMSWSPHHDARLVS 1356

Query: 638  NSGDYEILYWDIENGCKLIR 657
               D E   WD++ G  L +
Sbjct: 1357 VGYDAEAFVWDVQKGTALAQ 1416

 Score = 30.4 bits (67), Expect = 3.3,   Method: Compositional matrix adjust.
 Identities = 17/69 (24%), Positives = 33/69 (47%)
 Frame = +1

Query: 698  HNRRVIAVADDFCKVHLFQYPCSKAKAPSHKYSAHSSHVTNVSFTHNDSHLISTGGKDMS 757
            H+ R+++V  D      F +   K  A + ++  H   +    F+  D  L+ TGG D S
Sbjct: 1336 HDARLVSVGYD---AEAFVWDVQKGTALA-QFKGHMGRLLTCQFSGLDPDLVMTGGSDAS 1503

Query: 758  IIQWKLVEK 766
            +  W++ ++
Sbjct: 1504 VHVWRVSQQ 1530
>30295
          Length = 593

 Score = 32.0 bits (71), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 26/101 (25%), Positives = 46/101 (45%), Gaps = 2/101 (1%)
 Frame = +2

Query: 550 GTHSGRWFVLDAETRDLVSIHTDGNEQLSVMRYSVDGTLLAVGSHDNFIYLYTV--LENG 607
            +  G+  V D  T + V      +  +    Y+  G  +A G  DN   +Y++   E  
Sbjct: 299 ASQDGKLIVWDGYTTNKVHAIPLRSSWVMTCAYAPSGGYVACGGLDNICSIYSLKTREGN 478

Query: 608 RKYSRYGKCTGHSSYITHLDWSPDNKHIMSNSGDYEILYWD 648
            + SR  +  GH+ Y++   +  DN+ I+++SGD     WD
Sbjct: 479 VRVSR--ELPGHTGYLSCCRFIDDNQ-IVTSSGDMTCALWD 592
>20662
          Length = 1220

 Score = 31.6 bits (70), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 12/38 (31%), Positives = 24/38 (63%), Gaps = 1/38 (2%)
 Frame = +2

Query: 488 QGHTDELWGLATHPFKD-LLLTCAQDRQVCMWNSVEHR 524
           + H+D +W +  HP +  L L+C+QD ++ +W+  E +
Sbjct: 500 RAHSDIVWDVQCHPTEPALFLSCSQDGKIVLWDVRESK 613
>19949
          Length = 903

 Score = 31.2 bits (69), Expect = 1.7,   Method: Compositional matrix adjust.
 Identities = 21/67 (31%), Positives = 31/67 (46%)
 Frame = +2

Query: 586 GTLLAVGSHDNFIYLYTVLENGRKYSRYGKCTGHSSYITHLDWSPDNKHIMSNSGDYEIL 645
           G   A GS D  + L+ +   G  Y+      GH+  +  L +SPD + I S S D  + 
Sbjct: 29  GAYTASGSMDCNVKLWDIRRKGCIYTY----KGHTGCVCCLRFSPDGRWIASASEDGLVK 196

Query: 646 YWDIENG 652
            WD+  G
Sbjct: 197 LWDLTAG 217
>03156
          Length = 1014

 Score = 31.2 bits (69), Expect = 1.8,   Method: Compositional matrix adjust.
 Identities = 36/186 (19%), Positives = 65/186 (34%), Gaps = 32/186 (17%)
 Frame = +1

Query: 618 GHSSYITHLDWSPDNKHIMSNSGDYEILYWDIENGCKLIRN---RSDCKDIDWTTYTCVL 674
           GH   +T +  + DN  + S S D  +  WD+E G  L +N   ++   D+ W   + + 
Sbjct: 175 GHDMVVTAIHLNTDNTLLCSGSRDNTVRIWDVETGACLRQNNIPQNLVTDVKWLPGSHL- 351

Query: 675 GFQVFGVWPEGSDGTDINALVRSHNRRVIAVADDFCKVHLFQYPCSKAK----------- 723
                 +   G D       VR ++ R + +   F K    Q  C               
Sbjct: 352 ------IIQAGEDKE-----VRIYDSRTLGIVRSFTKKQYIQMSCDVTADGQFCLTCSNG 498

Query: 724 ----------------APSHKYSAHSSHVTNVSF--THNDSHLISTGGKDMSIIQWKLVE 765
                           +  +++  H   +    F  ++ D  LI+T  +D S+  W +  
Sbjct: 499 FGGNGCEATLWQLSDGSIQNEFKGHREAIEACLFLPSNQDMTLIATASRDCSVRVWNMFT 678

Query: 766 KLPVPQ 771
           K  V +
Sbjct: 679 KECVCE 696
>06563
          Length = 2303

 Score = 31.2 bits (69), Expect = 2.1,   Method: Compositional matrix adjust.
 Identities = 22/90 (24%), Positives = 36/90 (40%)
 Frame = -2

Query: 167  RGKDCRANVYLLPTGEIVYFIASVVVLFNYEERTQRHYLGHTDCVRCLAVHPDKIRIATG 226
            +GK C+A  Y      + +  A  V +      T +  L  T     L   P    +AT 
Sbjct: 2215 QGKTCKAMAYSADGRLLAWATADCVYVMXVSTYTVKQQLQQTRVAE-LMFSPRGSVLATW 2039

Query: 227  QIAGVDKDGRPLQPHVRVWDSVSLTTLHVI 256
                +D+DG+  +P++ +WD  S   L   
Sbjct: 2038 GPFYMDRDGKGGEPNMVIWDXASGNVLKTF 1949
>01327
          Length = 2215

 Score = 30.8 bits (68), Expect = 2.4,   Method: Compositional matrix adjust.
 Identities = 36/186 (19%), Positives = 65/186 (34%), Gaps = 32/186 (17%)
 Frame = +3

Query: 618 GHSSYITHLDWSPDNKHIMSNSGDYEILYWDIENGCKLIRN---RSDCKDIDWTTYTCVL 674
           GH   +T +  + DN  + S S D  +  WD+E G  L +N   ++   D+ W   + + 
Sbjct: 285 GHDMVVTAIHLNTDNTLLCSGSRDNTVRIWDVETGACLRQNNIPQNLVTDVKWLPGSHL- 461

Query: 675 GFQVFGVWPEGSDGTDINALVRSHNRRVIAVADDFCKVHLFQYPCSKAK----------- 723
                 +   G D       VR ++ R + +   F K    Q  C               
Sbjct: 462 ------IIQAGEDKE-----VRIYDSRTLGIVRSFTKKQYIQMSCDVTADGQFCLTCSNG 608

Query: 724 ----------------APSHKYSAHSSHVTNVSF--THNDSHLISTGGKDMSIIQWKLVE 765
                           +  +++  H   +    F  ++ D  LI+T  +D S+  W +  
Sbjct: 609 FGGNGCEATLWQLSDGSIQNEFKGHREAIEACLFLPSNQDMTLIATASRDCSVRVWNMFT 788

Query: 766 KLPVPQ 771
           K  V +
Sbjct: 789 KECVCE 806
>01249
          Length = 1743

 Score = 30.8 bits (68), Expect = 2.6,   Method: Compositional matrix adjust.
 Identities = 12/35 (34%), Positives = 23/35 (65%)
 Frame = -1

Query: 618 GHSSYITHLDWSPDNKHIMSNSGDYEILYWDIENG 652
           GHS  +T L +S D + + S S + +++ W++E+G
Sbjct: 921 GHSDAVTCLAFSSDGQRLASGSQNGKVIIWNMESG 817

 Score = 29.6 bits (65), Expect = 5.4,   Method: Compositional matrix adjust.
 Identities = 18/57 (31%), Positives = 29/57 (50%)
 Frame = -1

Query: 201 QRHYLGHTDCVRCLAVHPDKIRIATGQIAGVDKDGRPLQPHVRVWDSVSLTTLHVIG 257
           +R   GH+D V CLA   D  R+A+G      ++G+ +  ++   DS SL     +G
Sbjct: 936 ERVLQGHSDAVTCLAFSSDGQRLASGS-----QNGKVIIWNMESGDSTSLDISGAVG 781
>05408
          Length = 931

 Score = 30.4 bits (67), Expect = 3.3,   Method: Compositional matrix adjust.
 Identities = 28/81 (34%), Positives = 40/81 (49%), Gaps = 9/81 (11%)
 Frame = +3

Query: 701 RVIAVADDFCKVHLFQYPCSKAKAPSHKYSAHSSH--VTNVSFTHNDSH-LISTG----- 752
           +VI    DF + HL    C K+K  +  +S  S+H  VT+ S TH D H L+ T      
Sbjct: 90  KVILFTTDFNQPHL--R*CLKSKYLASTFSIFSAHKTVTDYSVTHKDGHRLVKTQRLW*N 263

Query: 753 -GKDMSIIQWKLVEKLPVPQN 772
             +D +I +W  V  L + QN
Sbjct: 264 LTEDQAICEWHAV--LRITQN 320
>12841
          Length = 1364

 Score = 30.4 bits (67), Expect = 3.3,   Method: Compositional matrix adjust.
 Identities = 29/117 (24%), Positives = 50/117 (42%), Gaps = 9/117 (7%)
 Frame = +1

Query: 566  LVSIHTDGNEQLSVMRYSVDGTLLAVGSHDNFIYLYTVLENGRKYSRYGKCTGHSSYITH 625
             +S H  G   L    +S D  +   G+ + +I+  +   N +    Y   +GH++ + H
Sbjct: 904  FISRHAGG---LCFDFHSRDLNVYLAGTEEGYIHKCSCSYNEQYLETY---SGHTAPVYH 1065

Query: 626  LDWSPDNKHI-MSNSGDYEILYWDIENGCKLIRNRSDCK---DIDW-----TTYTCV 673
            + WSP    I +S S D+ I  W  +    ++   S  K   D+ W     T + CV
Sbjct: 1066 IRWSPFVSDIFLSCSADWSIRLWHQDRTTPILTFHSSTKTVHDVCWSPRSSTVFACV 1236
>34005
          Length = 456

 Score = 30.4 bits (67), Expect = 3.5,   Method: Compositional matrix adjust.
 Identities = 13/40 (32%), Positives = 19/40 (47%)
 Frame = +1

Query: 609 KYSRYGKCTGHSSYITHLDWSPDNKHIMSNSGDYEILYWD 648
           + +R+G C      +  L WSPD   + S S D  +  WD
Sbjct: 79  RATRWGFCPLTPQEVCGLSWSPDATFLASGSNDNSVNIWD 198
>03395
          Length = 2795

 Score = 30.0 bits (66), Expect = 4.2,   Method: Compositional matrix adjust.
 Identities = 26/101 (25%), Positives = 41/101 (40%), Gaps = 1/101 (0%)
 Frame = +2

Query: 554 GRWFVLDAET-RDLVSIHTDGNEQLSVMRYSVDGTLLAVGSHDNFIYLYTVLENGRKYSR 612
           G W V D    R+L    T     + + R   DG  +  G  D+ + L+   E    ++ 
Sbjct: 344 GYWEVGDGGLLRELEGSQTGAINTIDIDR---DGQTILTGGEDSLLKLWRYNEGEVTHTG 514

Query: 613 YGKCTGHSSYITHLDWSPDNKHIMSNSGDYEILYWDIENGC 653
            G    HS+ IT     P+  +I+S   D  +  W   +GC
Sbjct: 515 IG----HSNQITKARICPNRHYIVSGGEDGALHIWKFPDGC 625
>27475
          Length = 369

 Score = 29.6 bits (65), Expect = 4.8,   Method: Compositional matrix adjust.
 Identities = 15/40 (37%), Positives = 24/40 (60%), Gaps = 3/40 (7%)
 Frame = +2

Query: 615 KC--TGHSSYITHLDWSPDNKHI-MSNSGDYEILYWDIEN 651
           KC  T H+ ++T +DWSP  +H+ +S S D  +  WD  +
Sbjct: 47  KCAFTSHTGWVTGVDWSPTREHLFLSGSYDNVLKLWDTRS 166
>04524
          Length = 1340

 Score = 29.6 bits (65), Expect = 5.1,   Method: Compositional matrix adjust.
 Identities = 11/41 (26%), Positives = 24/41 (58%)
 Frame = -1

Query: 610 YSRYGKCTGHSSYITHLDWSPDNKHIMSNSGDYEILYWDIE 650
           Y+ +  C GH+ ++  L +  + + ++S SGD  +  W++E
Sbjct: 929 YNIHTYCLGHTQFVNCLVYVEEFRVLISGSGDCTVRAWNME 807
>27681
          Length = 465

 Score = 26.9 bits (58), Expect(2) = 5.5,   Method: Compositional matrix adjust.
 Identities = 10/28 (35%), Positives = 20/28 (71%)
 Frame = +2

Query: 574 NEQLSVMRYSVDGTLLAVGSHDNFIYLY 601
           N+ ++ + ++ +GTLLA GS+D +  L+
Sbjct: 161 NKDVTSLDWNSEGTLLATGSYDGYARLW 244

 Score = 21.2 bits (43), Expect(2) = 5.5,   Method: Composition-based stats.
 Identities = 9/30 (30%), Positives = 14/30 (46%)
 Frame = +3

Query: 623 ITHLDWSPDNKHIMSNSGDYEILYWDIENG 652
           I  L W+    +I+S   D   + WD  +G
Sbjct: 294 IFALKWNKRGNYILSAGVDKTTIIWDASSG 383
>01805
          Length = 2124

 Score = 29.6 bits (65), Expect = 5.8,   Method: Compositional matrix adjust.
 Identities = 35/173 (20%), Positives = 62/173 (35%), Gaps = 21/173 (12%)
 Frame = -1

Query: 617 TGHSSYITHLDWSPDNKHIM-SNSGDYEILYWDIENG---CKLIRNRSDCKDIDW----- 667
           TGH+  +  L W+ + +H++ S S D  +  WD+  G       ++  + +  +W     
Sbjct: 585 TGHTQAVLDLSWNRNARHVLASASADTTVALWDLSEGKMAMNFTQHSREVQCCNWHPQEE 406

Query: 668 ------------TTYTCVLGFQVFGVWPEGSDGTDINALVRSHNRRVIAVADDFCKVHLF 715
                           C         W    +G    A+   HN   +    D   V+ F
Sbjct: 405 QTLLTGSFDNTVKVVDCRSAETCHKSWT--VEGEVEKAVWNHHNPLQLLACTDKGMVYCF 232

Query: 716 QYPCSKAKAPSHKYSAHSSHVTNVSFTHNDSHLISTGGKDMSIIQWKLVEKLP 768
                + + P     AHSS VT V  +     L+ T  +D ++  W + +  P
Sbjct: 231 DI---RHEKPVFSVGAHSSCVTGVCLSSQIPGLMITTSEDKTMKVWDIQDDKP 82
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|19527256|ref|NP_598801.1| DEAD (Asp-Glu-Ala-Asp) box
polypeptide 1 [Mus musculus]
         (740 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

00621                                                                 111   9e-25
09316                                                                 108   6e-24
00739                                                                 102   8e-22
01517                                                                  99   8e-21
09327                                                                  92   7e-19
01062                                                                  90   3e-18
34295                                                                  86   7e-17
00162                                                                  83   3e-16
19640                                                                  82   7e-16
00617                                                                  81   1e-15
07310                                                                  81   1e-15
02054                                                                  78   1e-14
03733                                                                  78   1e-14
09819                                                                  74   2e-13
04883                                                                  72   5e-13
22006                                                                  71   1e-12
11624                                                                  70   2e-12
39583                                                                  70   4e-12
12995                                                                  69   1e-11
14337                                                                  67   2e-11
02498                                                                  61   2e-09
19525                                                                  56   4e-08
17708                                                                  56   6e-08
19151                                                                  54   3e-07
08036                                                                  54   3e-07
33025                                                                  53   5e-07
17544                                                                  50   4e-06
11160                                                                  49   7e-06
10649                                                                  49   1e-05
31220                                                                  46   7e-05
12121                                                                  44   3e-04
19172                                                                  43   5e-04
33083                                                                  41   0.001
11423                                                                  38   0.014
06438                                                                  38   0.015
30136                                                                  38   0.015
31899                                                                  36   0.066
33543                                                                  35   0.16 
03381                                                                  34   0.21 
34134                                                                  32   0.89 
>00621
          Length = 2263

 Score =  111 bits (278), Expect = 9e-25,   Method: Compositional matrix adjust.
 Identities = 89/348 (25%), Positives = 153/348 (43%), Gaps = 2/348 (0%)
 Frame = +1

Query: 285 NAPKALIVEPSRELAEQTLNNVKQFKKYIDNPKLRELLIIGGVAARDQLSVLDNGVDIVV 344
             P A+I+ P+RELA+Q     ++F + +    +R + +IGG++  +Q   L  G ++V+
Sbjct: 481 QGPYAVILAPTRELAQQIEEETRKFGEGLG---IRVVSVIGGISREEQGFKLQQGCEVVI 651

Query: 345 GTPGRLDDLVSTGKLNLSQVRFLVLDEADGLLSQGYSDFINRMHNQIPQITCDGKRLQVI 404
            TPGR+ D++    L L+Q  ++V+DEAD +++ G+   + ++ + +P            
Sbjct: 652 ATPGRMIDVLENRYLVLNQCTYVVMDEADRMINMGFEPEVRKILDYLPVSNQKPDNDDAE 831

Query: 405 VCSATLHSFDVK-KLSEKIMHFPTWVDLKGEDSXXXXXXXXXXXXNPKTDKLWERLGKNH 463
                L +F  K K  + +M   T                      P+     ERL +  
Sbjct: 832 DDLKMLQNFKSKHKYRQTVMFTAT--------------------MPPQV----ERLARTF 939

Query: 464 IRTDDVHAKDNT-RPGANSPEMWSEAIKILKGEYAVRAIKEHKMDQAIIFCRTKIDCDNL 522
           +R   V    N  +P     ++     +  K +  +  +        IIF   K   D L
Sbjct: 940 LRRPTVVYIGNVGKPVERVEQIVYMLTESEKRKKLIEVLNAGVDPPIIIFVNQKKGADVL 1119

Query: 523 EQYFMQQGGGPDKKGHQFSCVCLHGDRKPHERKQNLERFKKGDVRFLICTDVAARGIDIH 582
            +   + G         F+   LHG +   +R+  L   K G    ++ TDVA RGIDI 
Sbjct: 1120AKSLEKMG---------FNATTLHGGKGQEQREYALASLKGGAKDIMVATDVAGRGIDIK 1272

Query: 583 GVPYVINVTLPDEKQNYVHRIGRVGRAERMGLAISLVATEKEKVWYHV 630
            V  V+N  +    ++Y HRIGR GRA + G +I+ +  E   V+Y +
Sbjct: 1273DVSLVLNYDMARTIEDYTHRIGRTGRAGKEGTSITFLTKEDSMVFYDL 1416

 Score = 47.4 bits (111), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 23/57 (40%), Positives = 38/57 (66%)
 Frame = +1

Query: 5   SEMGVMPEIAQAVEEMDWLLPTDIQAESIPLILGGGDVLMAAETGSGKTGAFSIPVI 61
           S++G   +I + ++ + +  PT IQ ++IP+ L   D++  AETGSGKT AF IP++
Sbjct: 268 SDLGA--DIMEVIDRVGYKEPTPIQMQAIPIGLQNRDIIGVAETGSGKTAAFLIPLL 432
>09316
          Length = 2312

 Score =  108 bits (271), Expect = 6e-24,   Method: Compositional matrix adjust.
 Identities = 96/340 (28%), Positives = 156/340 (45%), Gaps = 4/340 (1%)
 Frame = +2

Query: 289  ALIVEPSRELAEQTLNNVKQFKKYIDNPKLRELLIIGGVAARDQLSVLD-NGVDIVVGTP 347
             L++  +RELA Q     ++F KY++N K+   +  GG++ +    VL  N   IVVGTP
Sbjct: 1058 VLVMAHTRELAFQISKEYERFSKYMNNVKIA--VFFGGMSVKKDEEVLSKNCPHIVVGTP 1231

Query: 348  GRLDDLVSTGKLNLSQVRFLVLDEADGLLSQGYSDF-INRMHNQIPQITCDGKRLQVIVC 406
            GRL  L     LNL +++  +LDE D +L+    D  + R   +I ++T   K  QV++ 
Sbjct: 1232 GRLHALAKANNLNLKKIKHFILDECDKMLA----DLDMRRDVQEIFRLTPHEK--QVMMF 1393

Query: 407  SATLHSFDVKKLSEKIMHFP--TWVDLKGEDSXXXXXXXXXXXXNPKTDKLWERLGKNHI 464
            SATL S +++ + +K M  P   +VD   +DS                     +L  + +
Sbjct: 1394 SATL-SKEIRPICKKFMQDPMEVYVD---DDS---------------------KLTLHGL 1498

Query: 465  RTDDVHAKDNTRPGANSPEMWSEAIKILKGEYAVRAIKEHKMDQAIIFCRTKIDCDNLEQ 524
            +      KDN +          E + +L+             +Q IIF ++   C  L Q
Sbjct: 1499 QQHYCKLKDNEKNRK-----LFELLDVLE------------FNQVIIFVKSVPRCMALSQ 1627

Query: 525  YFMQQGGGPDKKGHQFSCVCLHGDRKPHERKQNLERFKKGDVRFLICTDVAARGIDIHGV 584
              ++Q          F  + +H      ER    ++FK    R L+ T++  RG+DI  V
Sbjct: 1628 LLLEQN---------FPAIAIHRQMTQEERLSRYQQFKDFQKRILVATNLFGRGMDIERV 1780

Query: 585  PYVINVTLPDEKQNYVHRIGRVGRAERMGLAISLVATEKE 624
              V N  +P++   Y+HR+ R GR    GLAI+ V+ E +
Sbjct: 1781 NIVFNYDMPEDSDTYLHRVARAGRFGTKGLAITFVSDEND 1900

 Score = 42.0 bits (97), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 19/61 (31%), Positives = 35/61 (57%)
 Frame = +2

Query: 2   AAFSEMGVMPEIAQAVEEMDWLLPTDIQAESIPLILGGGDVLMAAETGSGKTGAFSIPVI 61
           + F +  + PE+ +A+ +  +  P+++Q E IP  +   DVL  A++G GKT  F +  +
Sbjct: 845 SGFRDFLLKPELLRAIIDCGFEHPSEVQHECIPQAILSMDVLCQAKSGMGKTAVFVLATL 1024

Query: 62  Q 62
           Q
Sbjct: 1025Q 1027
>00739
          Length = 1313

 Score =  102 bits (253), Expect = 8e-22,   Method: Compositional matrix adjust.
 Identities = 89/285 (31%), Positives = 127/285 (44%), Gaps = 6/285 (2%)
 Frame = +3

Query: 342 IVVGTPGRLDDLV-STGKLNLSQVRFLVLDEADGLLSQGYSDFINRMHNQIPQITCDGKR 400
           IV+ TPGRL D + S    +L +V+FLV+DEAD LL   +   +  +  ++P        
Sbjct: 48  IVISTPGRLADHIDSCDTFSLKRVKFLVMDEADRLLDDNFGAQLEPILTRLPSAR----- 212

Query: 401 LQVIVCSATLHSFDVKKLSEKIMHFP-TWVDLKGEDSXXXXXXXXXXXXNPKTDKLWERL 459
            Q ++ SATL S  V  L + +++ P  W+                        +  ER 
Sbjct: 213 -QTLLFSATL-SPTVNALRDSVLNKPFVWI------------------------QQSERA 314

Query: 460 GKNHIRTDDVHAKDNTRPGANSPEMWSEAIKILKGEYAVRAI----KEHKMDQAIIFCRT 515
             + ++ D V       P +            +K  Y V  +    K+H     IIF  T
Sbjct: 315 TVDELQEDYVLV-----PAS------------MKDAYMVHILDHWLKDHPRSSLIIFTXT 443

Query: 516 KIDCDNLEQYFMQQGGGPDKKGHQFSCVCLHGDRKPHERKQNLERFKKGDVRFLICTDVA 575
              C    +Y    G   +K   QFSC  LH       R  +L RFK    R LI TDVA
Sbjct: 444 ---C----KYAQILGMMLEKL--QFSCAVLHSMIPQRFRLSSLSRFKSNQTRILISTDVA 596

Query: 576 ARGIDIHGVPYVINVTLPDEKQNYVHRIGRVGRAERMGLAISLVA 620
           +RG+DI  V  +IN  +P+  ++YVHR+GR  RA R G +ISLV 
Sbjct: 597 SRGLDIPTVDLIINHNIPNRPRDYVHRVGRTARAGRCGQSISLVT 731
>01517
          Length = 2605

 Score = 98.6 bits (244), Expect = 8e-21,   Method: Compositional matrix adjust.
 Identities = 78/267 (29%), Positives = 117/267 (43%)
 Frame = +2

Query: 352 DLVSTGKLNLSQVRFLVLDEADGLLSQGYSDFINRMHNQIPQITCDGKRLQVIVCSATLH 411
           D++  GK+ +    +LVLDEAD +L  G+   I R+  +   +   G+R Q ++ SAT  
Sbjct: 5   DMMERGKIGMDHCNYLVLDEADRMLDMGFEPQIRRIVEK-DTMPPTGQR-QTLMFSAT-- 172

Query: 412 SFDVKKLSEKIMHFPTWVDLKGEDSXXXXXXXXXXXXNPKTDKLWERLGKNHIRTDDVHA 471
                        FP  + L   D                 + ++  +G+    ++++  
Sbjct: 173 -------------FPKEIQLLARDFL--------------DNYIFLAVGRVGSTSENITQ 271

Query: 472 KDNTRPGANSPEMWSEAIKILKGEYAVRAIKEHKMDQAIIFCRTKIDCDNLEQYFMQQGG 531
           K         PE  S  + +L       A         ++F  TK   D+LEQ+ M +  
Sbjct: 272 K---VVWVEEPEKRSFLLDLLM------ASGTGPESLTLVFVETKKGADSLEQFLMYE-- 418

Query: 532 GPDKKGHQFSCVCLHGDRKPHERKQNLERFKKGDVRFLICTDVAARGIDIHGVPYVINVT 591
                   +    +HGDR   ER+  L  FK GD   L+ T VAARG+DI  V +VIN  
Sbjct: 419 -------NYPATSIHGDRSQREREDALRVFKNGDRPILVATAVAARGLDIPNVRHVINFD 577

Query: 592 LPDEKQNYVHRIGRVGRAERMGLAISL 618
           LP + + YVHRIGR GR   +GLA S 
Sbjct: 578 LPSDIEEYVHRIGRTGRVGNLGLATSF 658
>09327
          Length = 1087

 Score = 92.0 bits (227), Expect = 7e-19,   Method: Compositional matrix adjust.
 Identities = 82/294 (27%), Positives = 136/294 (46%), Gaps = 5/294 (1%)
 Frame = +2

Query: 291 IVEPSRELAEQTLNNVKQFKKYIDNPKLRELLIIGGVAARDQLSVLDNGVDIVVGTPGRL 350
           ++ P+RELA+Q      +F     + ++R + + GG     QL  LD G +I + TPGRL
Sbjct: 20  LLVPTRELAQQVQEVAVEFGH---SSRVRSVCVYGGAQRGPQLRELDRGAEICIATPGRL 190

Query: 351 DDLVSTGKLNLSQVRFLVLDEADGLLSQGYSDFINRMHNQIPQITCDGKRLQVIVCSATL 410
            D + + + NL +  +LVLDEAD +L  G+   I ++   + QI  D    Q ++ SAT 
Sbjct: 191 IDFLESNRTNLRRCTYLVLDEADRMLDMGFEPQIRKI---VEQIRPDR---QTLMWSATW 352

Query: 411 HSFDVKKLSEKIMHFPTWVDLKGEDSXXXXXXXXXXXXNPKTDKLWERLGKNH--IRTDD 468
              +V+KL+E  +   T +++                          +L  NH  ++  D
Sbjct: 353 PK-EVRKLAEDFIMEYTQINIGA-----------------------LQLTANHNILQIID 460

Query: 469 V---HAKDNTRPGANSPEMWSEAIKILKGEYAVRAIKEHKMDQAIIFCRTKIDCDNLEQY 525
           V   H K+             + +K+L        I + K ++ +IF  TK  CD++ + 
Sbjct: 461 VCMDHEKE------------EKLVKLLN------EIMQEKENRTLIFVETKRKCDDIHRR 586

Query: 526 FMQQGGGPDKKGHQFSCVCLHGDRKPHERKQNLERFKKGDVRFLICTDVAARGI 579
            M++ G P         +C+HGD+   ER   L  F+ G    L+ TDVA+RG+
Sbjct: 587 -MKRDGWP--------VLCIHGDKSQQERDWVLNDFRNGRCPVLLATDVASRGL 721
>01062
          Length = 2138

 Score = 90.1 bits (222), Expect = 3e-18,   Method: Compositional matrix adjust.
 Identities = 51/140 (36%), Positives = 76/140 (54%)
 Frame = -3

Query: 506  MDQAIIFCRTKIDCDNLEQYFMQQGGGPDKKGHQFSCVCLHGDRKPHERKQNLERFKKGD 565
            + QA+IFC TK   D L +           +   F+   +HGD    ER+  ++ F+ GD
Sbjct: 1362 ITQAVIFCNTKRKVDWLTEKM---------REANFTVSSMHGDMPQKEREAIMKVFRAGD 1210

Query: 566  VRFLICTDVAARGIDIHGVPYVINVTLPDEKQNYVHRIGRVGRAERMGLAISLVATEKEK 625
             R LI TDV ARGID+  V  VIN  LP+ ++ Y+HRIGR GR  R G+AI+ V  +  +
Sbjct: 1209 SRVLITTDVWARGIDVQQVSLVINYDLPNNRELYIHRIGRSGRFGRKGVAINFVKNDDIR 1030

Query: 626  VWYHVCSNRGKGCYNTRLKE 645
            +   +     +  Y+T++ E
Sbjct: 1029 ILRDI-----EQYYSTQIDE 985

 Score = 68.2 bits (165), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 46/148 (31%), Positives = 81/148 (54%)
 Frame = -3

Query: 288  KALIVEPSRELAEQTLNNVKQFKKYIDNPKLRELLIIGGVAARDQLSVLDNGVDIVVGTP 347
            +ALI+ P+RELA Q    +     Y++   ++    IGG    + +  LD G  IV GTP
Sbjct: 1869 QALILSPTRELATQIQKVMLALGDYMN---VQCHSCIGGTNIGEDIRKLDYGQHIVSGTP 1699

Query: 348  GRLDDLVSTGKLNLSQVRFLVLDEADGLLSQGYSDFINRMHNQIPQITCDGKRLQVIVCS 407
            GR+ D++    L    ++ ++LDEAD +L++G+ + I  ++  +P  T      QVI+ S
Sbjct: 1698 GRVFDMIKRRNLRTRSIKMMILDEADEMLNKGFKEQIYDVYRYLPPAT------QVILIS 1537

Query: 408  ATLHSFDVKKLSEKIMHFPTWVDLKGED 435
            ATL   ++ +++ K M  P  + +K ++
Sbjct: 1536 ATL-PHEILEMTNKFMTDPIRILVKRDE 1456

 Score = 47.0 bits (110), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 23/70 (32%), Positives = 40/70 (57%)
 Frame = -3

Query: 3    AFSEMGVMPEIAQAVEEMDWLLPTDIQAESIPLILGGGDVLMAAETGSGKTGAFSIPVIQ 62
             F  MG+  E+ + +    +  P+ IQ  ++  I+ G DV+  A++G+GKT  FSI V+Q
Sbjct: 2076 TFDNMGIREELLRGIYAYGFEKPSAIQQRAVKPIVKGRDVIAQAQSGTGKTATFSISVLQ 1897

Query: 63   IVYETLKDQQ 72
             +   L++ Q
Sbjct: 1896 CLDIQLRETQ 1867
>34295
          Length = 694

 Score = 85.5 bits (210), Expect = 7e-17,   Method: Compositional matrix adjust.
 Identities = 49/116 (42%), Positives = 60/116 (51%)
 Frame = -1

Query: 503 EHKMDQAIIFCRTKIDCDNLEQYFMQQGGGPDKKGHQFSCVCLHGDRKPHERKQNLERFK 562
           E K+   +IF  TK  C  L                +   VCLHG  +  ER   L RFK
Sbjct: 553 E*KIPNVMIFTNTKKYCQLLSMTLTNM---------EIENVCLHGFMRQKERVSALSRFK 401

Query: 563 KGDVRFLICTDVAARGIDIHGVPYVINVTLPDEKQNYVHRIGRVGRAERMGLAISL 618
              +R LI TDVAARG+DI  V  VIN  LP   + Y+HR+GR  RA R G+AIS+
Sbjct: 400 SNHIRTLIATDVAARGLDIPSVQLVINHMLPRTPKEYIHRVGRTARAGRKGVAISI 233
>00162
          Length = 2322

 Score = 83.2 bits (204), Expect = 3e-16,   Method: Compositional matrix adjust.
 Identities = 89/343 (25%), Positives = 151/343 (44%), Gaps = 6/343 (1%)
 Frame = +3

Query: 288 KALIVEPSRELAEQ---TLNNVKQFKKYIDNPKLRELLIIGGVAARDQLSVLDNGVDIVV 344
           +ALI+ P+RELA Q    LN ++ F  +  N      L+IGG     +  ++    +IV+
Sbjct: 141 EALIITPTRELAFQIYEVLNKIRTFHDFSAN------LVIGGKFMWRETHLM-GKTNIVI 299

Query: 345 GTPGRL-DDLVSTGKLNLSQVRFLVLDEADGLLSQGYSDFINRMHNQIPQITCDGKRLQV 403
            T GRL   L ST   ++S+++ LVLDEAD ++   ++  ++ + + +P         Q 
Sbjct: 300 CTVGRLLHHLESTQAFDVSELKVLVLDEADRIMDSKFAQDMDSIMSHLPP-------RQT 458

Query: 404 IVCSATLHSFDVKKLSEKIMHFPTWVDLKGEDSXXXXXXXXXXXXNPKTDKLWERLGKNH 463
           ++ SAT  +  VK L+   +  P++V +                                
Sbjct: 459 LLFSAT-QTMSVKTLARLSLKDPSYVSV-------------------------------- 539

Query: 464 IRTDDVHAKDNTRPGANSPEMWSEAIKILKGEYAVRAIKEHKMDQAIIFCRTKIDCDNLE 523
               D HA+  T  G     +  E  + L   Y+   +K H  ++ ++F +T      + 
Sbjct: 540 ----DRHAEYVTPTGLEQSYIVCELHEKLSLLYSF--LKNHPNNKIMVFLQTCKQARYVH 701

Query: 524 QYFMQQGGGPDKKGHQFSCVCLHGDRKPHERKQNLER-FKKGDVRFLICTDVAARGIDIH 582
               ++  G        S + LHG   P  R+ ++ R F +     LI TD+A RG+D  
Sbjct: 702 TVIKRERPG-------MSVLVLHGG-IPQLRRLDIYREFCRKQHVILITTDLACRGLDFP 857

Query: 583 GVPYVINVTLPDEKQNYVHRIGRVGRAERMGLA-ISLVATEKE 624
            V +VI +  P +   Y+HR GR  R E  G A + L+ +E+E
Sbjct: 858 AVNWVIQLDCPVDVNTYIHRAGRTARFECNGQALLVLLPSEEE 986

 Score = 35.4 bits (80), Expect = 0.087,   Method: Composition-based stats.
 Identities = 20/33 (60%), Positives = 23/33 (69%)
 Frame = +2

Query: 39 GGDVLMAAETGSGKTGAFSIPVIQIVYETLKDQ 71
          G DVL AA+TGSGKT AF IP++    ETL  Q
Sbjct: 32 GLDVLGAAKTGSGKTLAFLIPIL----ETLSKQ 118
>19640
          Length = 456

 Score = 82.0 bits (201), Expect = 7e-16,   Method: Composition-based stats.
 Identities = 39/97 (40%), Positives = 55/97 (56%)
 Frame = -1

Query: 511 IFCRTKIDCDNLEQYFMQQGGGPDKKGHQFSCVCLHGDRKPHERKQNLERFKKGDVRFLI 570
           IFC T+   D L Q         +   H F+   +HGD +  +R+  +++F+ G  R LI
Sbjct: 456 IFCNTRRKVDQLTQ---------EMSSHNFTVSAMHGDMEQRDREVIMKQFRSGSSRVLI 304

Query: 571 CTDVAARGIDIHGVPYVINVTLPDEKQNYVHRIGRVG 607
            TD+ ARGID+  V  VIN  LP  ++NY+HRIGR G
Sbjct: 303 TTDLLARGIDVQQVSLVINYDLPSNRENYIHRIGRGG 193
>00617
          Length = 1505

 Score = 81.3 bits (199), Expect = 1e-15,   Method: Compositional matrix adjust.
 Identities = 40/82 (48%), Positives = 50/82 (60%)
 Frame = -3

Query: 539  QFSCVCLHGDRKPHERKQNLERFKKGDVRFLICTDVAARGIDIHGVPYVINVTLPDEKQN 598
            QFSC  LH       R  +L RFK    R LI TDVA+RG+DI  V  +IN  +P+  ++
Sbjct: 1485 QFSCAVLHSMIPQRFRLSSLSRFKSNQTRILISTDVASRGLDIPTVDLIINHNIPNRPRD 1306

Query: 599  YVHRIGRVGRAERMGLAISLVA 620
            YVHR+GR  RA R G +ISLV 
Sbjct: 1305 YVHRVGRTARAGRCGQSISLVT 1240
>07310
          Length = 712

 Score = 81.3 bits (199), Expect = 1e-15,   Method: Compositional matrix adjust.
 Identities = 68/274 (24%), Positives = 118/274 (43%)
 Frame = +2

Query: 349 RLDDLVSTGKLNLSQVRFLVLDEADGLLSQGYSDFINRMHNQIPQITCDGKRLQVIVCSA 408
           R+ DL++   +       LVLDEAD LLSQ +   ++ +   +P       + Q+++ SA
Sbjct: 2   RILDLMNKRLVKPDTCGILVLDEADKLLSQDFKGMLDNIIAHLP------PQRQILLYSA 163

Query: 409 TLHSFDVKKLSEKIMHFPTWVDLKGEDSXXXXXXXXXXXXNPKTDKLWERLGKNHIRTDD 468
           T     V++  +K +  P  ++L                                   ++
Sbjct: 164 TF-PLSVEQFMKKYLKNPYEINL----------------------------------MEE 238

Query: 469 VHAKDNTRPGANSPEMWSEAIKILKGEYAVRAIKEHKMDQAIIFCRTKIDCDNLEQYFMQ 528
           +  K  T+  A   E   + +  L   ++     + +++Q+IIFC +    + L +   +
Sbjct: 239 LTLKGVTQYYAFVQE--KQKVHCLNTLFS-----KLQINQSIIFCNSTQRVELLAKKITE 397

Query: 529 QGGGPDKKGHQFSCVCLHGDRKPHERKQNLERFKKGDVRFLICTDVAARGIDIHGVPYVI 588
            G         +SC  +H       R +    F++G  R L+C+D+  RGIDI  V  VI
Sbjct: 398 LG---------YSCYYIHAKMNQQHRNRVFHDFRQGLCRNLVCSDLFTRGIDIQAVNVVI 550

Query: 589 NVTLPDEKQNYVHRIGRVGRAERMGLAISLVATE 622
           N   P   + Y+HRIGR GR   +G+AI+L+  E
Sbjct: 551 NFDFPKHAETYLHRIGRSGRYGHLGVAINLITFE 652
>02054
          Length = 1110

 Score = 77.8 bits (190), Expect = 1e-14,   Method: Compositional matrix adjust.
 Identities = 45/130 (34%), Positives = 69/130 (53%), Gaps = 2/130 (1%)
 Frame = -3

Query: 493 KGEYAVRAIKEHKMDQAIIFCRTKIDCDNLEQ--YFMQQGGGPDKKGHQFSCVCLHGDRK 550
           K  Y V  + E   +  ++FC T   C N ++    ++  G        F+ + LHG   
Sbjct: 679 KDAYLVSILNELAGNSFMVFCST---CANTQRVALLLRNLG--------FTAIPLHGQMS 533

Query: 551 PHERKQNLERFKKGDVRFLICTDVAARGIDIHGVPYVINVTLPDEKQNYVHRIGRVGRAE 610
             +R  +L +FK  D   LI TDVA+RG+DI  V  V+N+ +P   ++Y+HR+GR  RA 
Sbjct: 532 QAKRLGSLNKFKSKDRSILIATDVASRGLDIPHVDVVLNLDIPTHSKDYMHRVGRTARAG 353

Query: 611 RMGLAISLVA 620
           R G AI+ V+
Sbjct: 352 RSGRAITFVS 323

 Score = 45.1 bits (105), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 24/72 (33%), Positives = 42/72 (58%), Gaps = 1/72 (1%)
 Frame = -2

Query: 323  IIGGVAARDQLSVLDNGVDIVVGTPGRL-DDLVSTGKLNLSQVRFLVLDEADGLLSQGYS 381
            ++ G+    Q  +L     I++ TPGRL D L +T   +L  ++FLV+DEAD +L   + 
Sbjct: 1052 LLVGIDMSTQALMLGKKPHIIIATPGRLVDHLENTKGFSLRALKFLVMDEADRILDMNFQ 873

Query: 382  DFINRMHNQIPQ 393
            D ++++   IP+
Sbjct: 872  DEVDKILKVIPR 837
>03733
          Length = 1281

 Score = 77.8 bits (190), Expect = 1e-14,   Method: Compositional matrix adjust.
 Identities = 54/157 (34%), Positives = 71/157 (45%), Gaps = 17/157 (10%)
 Frame = +1

Query: 119 WHGCRGTRGLLKGKHYYEVSC-------------HDQGLCRVGWSTMQASXXXXXXXXXX 165
           W G R   G+  GK  YEV                +  + RVGWS    S          
Sbjct: 382 WAGARAMFGVKSGKFAYEVKLLEHLNVDHLPSDESNPHVLRVGWSVDDTSMQLGEEALSY 561

Query: 166 XXXXXXXXSHNKQFDNYGEEFTMHDTIGCYLDIDKGHV--KFSKNGKDLGLAFEIPA-HI 222
                   S   +F +YGE+FT  D I  YLD+D   V   F+KNG DLG  +E+    +
Sbjct: 562 GYGGTGKASTECKFKDYGEKFTSGDVITAYLDMDSDPVVLSFAKNGTDLGACYEVEKEQL 741

Query: 223 KNQALFPACVLKNAELKFNFG-EEEFKFPPKDGFVAL 258
            ++ALFP  + KN E + NFG +EE  FP K+ F  L
Sbjct: 742 GDRALFPHILTKNTEFECNFGAKEEPYFPLKEEFAFL 852
>09819
          Length = 1877

 Score = 74.3 bits (181), Expect = 2e-13,   Method: Compositional matrix adjust.
 Identities = 51/154 (33%), Positives = 68/154 (44%), Gaps = 17/154 (11%)
 Frame = +2

Query: 119 WHGCRGTRGLLKGKHYYEVSCHDQ-------------GLCRVGWSTMQASXXXXXXXXXX 165
           W G R   G+  GK  +EV   +               + RVGWS    S          
Sbjct: 212 WSGARAMYGVKAGKVAFEVKLTENLSVDHLPSDESHPHVLRVGWSADDTSMQLGEEALSY 391

Query: 166 XXXXXXXXSHNKQFDNYGEEFTMHDTIGCYLDIDKGHV--KFSKNGKDLGLAFEIPAH-I 222
                   S   QF +YGE FT  D I  YLD+D   V   F+KNG DLG  + +    +
Sbjct: 392 GYGGTGKASTECQFKDYGESFTAGDVITAYLDMDSDPVTMSFAKNGTDLGECYSVEKEKL 571

Query: 223 KNQALFPACVLKNAELKFNFG-EEEFKFPPKDGF 255
           +++ALFP  + KN E + NFG  EE  FP  +G+
Sbjct: 572 EDKALFPHILSKNTEFECNFGSREEPFFPLNEGY 673
>04883
          Length = 1155

 Score = 72.4 bits (176), Expect = 5e-13,   Method: Compositional matrix adjust.
 Identities = 47/139 (33%), Positives = 75/139 (53%)
 Frame = +3

Query: 285 NAPKALIVEPSRELAEQTLNNVKQFKKYIDNPKLRELLIIGGVAARDQLSVLDNGVDIVV 344
           + P  L + P+RELA+Q     ++F       ++R + + GG     QL  L+ G +I +
Sbjct: 576 DGPIVLALVPTRELAQQVQEVAQEFGHA---SRVRSVCVYGGAPRGPQLRDLERGAEICI 746

Query: 345 GTPGRLDDLVSTGKLNLSQVRFLVLDEADGLLSQGYSDFINRMHNQIPQITCDGKRLQVI 404
            TPGRL D + + + NL +  +LVLDEAD +L  G+   I ++   I QI  D    Q +
Sbjct: 747 ATPGRLIDFLESNRTNLRRCTYLVLDEADRMLDMGFEPQIRKI---IEQIRPD---RQTL 908

Query: 405 VCSATLHSFDVKKLSEKIM 423
           + SAT    +V+KL+E  +
Sbjct: 909 MWSATWPK-EVRKLAEDFI 962

 Score = 50.1 bits (118), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 23/59 (38%), Positives = 34/59 (57%)
 Frame = +3

Query: 3   AFSEMGVMPEIAQAVEEMDWLLPTDIQAESIPLILGGGDVLMAAETGSGKTGAFSIPVI 61
            F+E+     +   V    W  PT IQ++S P+ + G D++  A+TGSGKT AF +P I
Sbjct: 363 TFTEVNFPDYVMNQVRRNSWTAPTPIQSQSWPVAMAGKDLVGIAQTGSGKTLAFMLPAI 539
>22006
          Length = 3414

 Score = 71.2 bits (173), Expect = 1e-12,   Method: Compositional matrix adjust.
 Identities = 39/88 (44%), Positives = 55/88 (62%)
 Frame = +2

Query: 288  KALIVEPSRELAEQTLNNVKQFKKYIDNPKLRELLIIGGVAARDQLSVLDNGVDIVVGTP 347
            +ALI+ P+RELA QTL   K+  K++D   LR  +I+GG    DQ S L    DI++ TP
Sbjct: 3149 RALILSPTRELALQTLKFTKELGKFLD---LRAAVILGGDRMEDQFSALHQNPDIIIATP 3319

Query: 348  GRLDDLVSTGKLNLSQVRFLVLDEADGL 375
            GRL  ++   K +L +V ++V DEAD L
Sbjct: 3320 GRLLHVLVEMKKSLKEVIYVVFDEADRL 3403

 Score = 48.1 bits (113), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 20/39 (51%), Positives = 30/39 (76%)
 Frame = +2

Query: 24   LPTDIQAESIPLILGGGDVLMAAETGSGKTGAFSIPVIQ 62
            LPT IQ ++IP+I+ G D++  A TGSGKT AF +P+++
Sbjct: 3002 LPTPIQRKTIPVIMEGKDMVAMARTGSGKTAAFLVPMLE 3118
>11624
          Length = 2257

 Score = 70.5 bits (171), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 35/84 (41%), Positives = 53/84 (63%), Gaps = 1/84 (1%)
 Frame = -1

Query: 547 GDRKPHERKQN-LERFKKGDVRFLICTDVAARGIDIHGVPYVINVTLPDEKQNYVHRIGR 605
             R P ER++  L++F KG +  L+C+D  ARG+D+  V YVI+   P   + Y+HR+GR
Sbjct: 808 SSRLPGERRKKILKQFSKGKIDLLVCSDAMARGMDVDNVKYVISYDNPPYIKTYIHRVGR 629

Query: 606 VGRAERMGLAISLVATEKEKVWYH 629
             RA R G AISL+   ++K ++H
Sbjct: 628 TARAGRAGTAISLL---EKKEFFH 566

 Score = 53.1 bits (126), Expect = 4e-07,   Method: Compositional matrix adjust.
 Identities = 40/120 (33%), Positives = 66/120 (55%), Gaps = 10/120 (8%)
 Frame = -3

Query: 276  QVSQTKFLPNAPKALIVEPSRELAEQTLNNVKQFKKYIDNPKLRELLIIGGVA---ARDQ 332
            Q  + + +P+  +A+IV P R+LAEQ     + F  Y  +  L+  +++G       +D 
Sbjct: 1748 QCLKQRMVPHV-RAVIVLPVRDLAEQVY---QVFCHYCADTPLKVGIVVGKTVFNVEQDT 1581

Query: 333  L------SVLDNGVDIVVGTPGRL-DDLVSTGKLNLSQVRFLVLDEADGLLSQGYSDFIN 385
            L       V  + +DI+V TPGRL D + ST   +LS +RFLV+DEAD ++     D+++
Sbjct: 1580 LVKKRYGGVYHSVIDILVATPGRLVDHINSTPGFDLSHLRFLVIDEADRMMEDIKLDWLS 1401

 Score = 32.0 bits (71), Expect = 0.89,   Method: Compositional matrix adjust.
 Identities = 12/28 (42%), Positives = 22/28 (78%)
 Frame = -3

Query: 41   DVLMAAETGSGKTGAFSIPVIQIVYETL 68
            D+ ++A TGSGKT A+++P+IQ + + +
Sbjct: 1811 DICVSAPTGSGKTLAYTLPIIQCLKQRM 1728
>39583
          Length = 234

 Score = 69.7 bits (169), Expect = 4e-12,   Method: Composition-based stats.
 Identities = 29/57 (50%), Positives = 43/57 (75%)
 Frame = -3

Query: 553 ERKQNLERFKKGDVRFLICTDVAARGIDIHGVPYVINVTLPDEKQNYVHRIGRVGRA 609
           +R + L+RFK+G++  L+ TD+A+RG+DI GV  VIN T+P   ++YVHR+GR  RA
Sbjct: 175 QRLEALKRFKEGEIDVLLATDLASRGLDIEGVKTVINFTMPSTLKHYVHRVGRTARA 5
>12995
          Length = 1072

 Score = 68.6 bits (166), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 38/117 (32%), Positives = 60/117 (51%)
 Frame = +3

Query: 507 DQAIIFCRTKIDCDNLEQYFMQQGGGPDKKGHQFSCVCLHGDRKPHERKQNLERFKKGDV 566
           D  ++F  TK   + L     + G          +C  ++       RK ++ +F    V
Sbjct: 132 DLTVVFVATKHHVEYLNTLLTKCG---------IACTYIYSSLDQTARKIHVAKFTHKQV 284

Query: 567 RFLICTDVAARGIDIHGVPYVINVTLPDEKQNYVHRIGRVGRAERMGLAISLVATEK 623
           + ++ TD+AARGIDI  +  V+N   P + + +VHR+GRV RA R G A SLVA ++
Sbjct: 285 KVMLVTDLAARGIDIPQLDNVVNFHFPAKAKLFVHRVGRVARAGRSGTAYSLVAMDE 455
>14337
          Length = 693

 Score = 67.4 bits (163), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 40/108 (37%), Positives = 56/108 (51%), Gaps = 6/108 (5%)
 Frame = +2

Query: 544 CLHGDRKPHERKQNLERFKKGDVRFLICTDVAARGIDIHGVPYVINVTLPDEKQNYVHRI 603
            +H D+   ER   +  F +G V  L+CT++  RGID  G+  VIN   P    +Y+HRI
Sbjct: 143 AIHADKPQAERDATVRAFTEGRVWVLVCTELMGRGIDFKGINLVINYDFPTNAVSYIHRI 322

Query: 604 GRVGRAERMGLAISLVATEKEKVWYHVCSN--RGKGC----YNTRLKE 645
           GR GRA   G AI+   TE++       +N  +  GC    Y  RLK+
Sbjct: 323 GRTGRAGVPGRAITFF-TEQDVTHLRSIANIIKEAGCEVPEYMLRLKK 463
>02498
          Length = 1955

 Score = 61.2 bits (147), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 32/81 (39%), Positives = 50/81 (61%), Gaps = 6/81 (7%)
 Frame = +3

Query: 545  LHGDRKPHERKQNLERFKKGDVRFLICTDVAARGIDIHGVPYVINVTLPDEK------QN 598
            L G+    +R   ++RF++G  + LI T+V+ARGID+  V  V+N  LP  +      + 
Sbjct: 948  LTGELTIEQRAAIIKRFREGKEKVLITTNVSARGIDVEMVTVVVNFDLPVTQDWRPDCET 1127

Query: 599  YVHRIGRVGRAERMGLAISLV 619
            Y+HRIGR GR  + G+AI++V
Sbjct: 1128 YLHRIGRTGRFGKNGIAINMV 1190

 Score = 43.9 bits (102), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 44/145 (30%), Positives = 71/145 (48%), Gaps = 9/145 (6%)
 Frame = +1

Query: 256 VALSKAPDNYIVKSQH-TGNA------QVSQTKFLPNAPKALIVEPSRELAEQTLNNVKQ 308
           + L+  P N I +SQ  TG         +S+       P+ L + P+ ELA Q    +++
Sbjct: 232 ILLADPPVNMIAQSQSGTGKTAAFVLTMLSRVDISQTFPQCLCLAPTYELALQIGEVIEK 411

Query: 309 FKKYIDNPKLRELLIIGGVAARDQLSVLDNGVDIVVGTPGRLDDLVSTGK-LNLSQVRFL 367
             K++   ++R   + G    R +  VL     IV+GTPG + D     K L L ++R  
Sbjct: 412 MSKHMTGLEIR-YAVRGERVNRGE--VLSE--QIVIGTPGTVMDWSHRFKALPLEKLRVF 576

Query: 368 VLDEADGLLS-QGYSDFINRMHNQI 391
           VLDEAD ++S QG+ D   R+  ++
Sbjct: 577 VLDEADVMISMQGHQDQSTRIQKRL 651
>19525
          Length = 585

 Score = 56.2 bits (134), Expect = 4e-08,   Method: Composition-based stats.
 Identities = 43/126 (34%), Positives = 67/126 (53%), Gaps = 3/126 (2%)
 Frame = +2

Query: 288 KALIVEPSRELAEQTLNNVKQFKKYIDNPKLRELLIIGGVAARDQLSVLDNGVDIVVGTP 347
           + L++ P+RELA Q     +Q  +Y    K+   L  GG+  + Q + L    DIVV TP
Sbjct: 17  RVLVLVPTRELAVQVYQVGQQISQYT---KISICLAAGGLDIKGQEAALRLCPDIVVATP 187

Query: 348 GRL-DDLVSTGKLNLSQVRFLVLDEADGLLSQGYSDFINRMHNQIPQI--TCDGKRLQVI 404
           GRL D L +     ++ V  LVLDEAD +L + ++        Q+ +I   C+ +R Q +
Sbjct: 188 GRLIDHLHNAPNFTIAHVEILVLDEADRMLDEYFA-------AQMTEIIRMCNFQR-QTM 343

Query: 405 VCSATL 410
           + SAT+
Sbjct: 344 LFSATM 361
>17708
          Length = 882

 Score = 55.8 bits (133), Expect = 6e-08,   Method: Compositional matrix adjust.
 Identities = 31/75 (41%), Positives = 45/75 (60%), Gaps = 1/75 (1%)
 Frame = +1

Query: 279 QTKFLP-NAPKALIVEPSRELAEQTLNNVKQFKKYIDNPKLRELLIIGGVAARDQLSVLD 337
           + KF+P N    +I+ P+REL+ QT N + +  KY  +      LI+GGV   D++  L 
Sbjct: 631 KLKFMPRNGTGCIIISPTRELSMQTFNVLTELLKYHHH---TFGLIMGGVNRHDEVKKLK 801

Query: 338 NGVDIVVGTPGRLDD 352
            GV+I+V TPGRL D
Sbjct: 802 KGVNIIVATPGRLLD 846

 Score = 35.4 bits (80), Expect = 0.092,   Method: Compositional matrix adjust.
 Identities = 15/26 (57%), Positives = 22/26 (84%)
 Frame = +1

Query: 41  DVLMAAETGSGKTGAFSIPVIQIVYE 66
           D++ AA+TGSGKT AF IP I+++Y+
Sbjct: 556 DLMGAAKTGSGKTLAFLIPAIELMYK 633
>19151
          Length = 625

 Score = 53.5 bits (127), Expect = 3e-07,   Method: Composition-based stats.
 Identities = 30/63 (47%), Positives = 40/63 (63%), Gaps = 6/63 (9%)
 Frame = -3

Query: 567 RFLICTDVAARGIDIHGVPYVINVTLP-DEKQN-----YVHRIGRVGRAERMGLAISLVA 620
           + LI T+V +RGIDI  V  V+N  LP D + N     Y+HRIGR GR  + G+AI+L+ 
Sbjct: 623 KVLITTNVLSRGIDIEQVTIVVNFDLPIDLRGNADCETYLHRIGRTGRFGKSGIAINLID 444

Query: 621 TEK 623
            EK
Sbjct: 443 GEK 435
>08036
          Length = 1226

 Score = 53.5 bits (127), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 34/90 (37%), Positives = 51/90 (56%)
 Frame = +1

Query: 343 VVGTPGRLDDLVSTGKLNLSQVRFLVLDEADGLLSQGYSDFINRMHNQIPQITCDGKRLQ 402
           VVGTP R+   +  G L L  V+ LV+DEAD + S G+   + ++  ++P+I       Q
Sbjct: 1   VVGTPSRILAHLRAGHLELHTVQMLVVDEADLVFSFGHEADMKKLMEELPRIY------Q 162

Query: 403 VIVCSATLHSFDVKKLSEKIMHFPTWVDLK 432
             + SATL S DVK L + ++H P  + LK
Sbjct: 163 AFLMSATL-SEDVKALKKMVLHNPVILKLK 249

 Score = 48.9 bits (115), Expect = 7e-06,   Method: Compositional matrix adjust.
 Identities = 20/45 (44%), Positives = 27/45 (60%)
 Frame = +3

Query: 576 ARGIDIHGVPYVINVTLPDEKQNYVHRIGRVGRAERMGLAISLVA 620
           ARGID   V  VIN   P     Y+HR+GR  R ++ G A+SL++
Sbjct: 612 ARGIDFQNVSNVINFEFPKTVDAYIHRVGRTARGDKQGCALSLIS 746
>33025
          Length = 558

 Score = 52.8 bits (125), Expect = 5e-07,   Method: Compositional matrix adjust.
 Identities = 32/106 (30%), Positives = 58/106 (54%), Gaps = 3/106 (2%)
 Frame = +3

Query: 322 LIIGGVAARDQLSVLDNGVDIVVGTPGRLDDLVSTGKLNLSQVRFLVLDEADGLLSQGYS 381
           ++ G    R Q S +  G ++VVGTPGRL D +    ++L + ++L+LDEAD +L  G+ 
Sbjct: 54  VVYGATDRRYQKSRIMKGANLVVGTPGRLLDFIGDQTISLGKCQYLILDEADRMLDMGFE 233

Query: 382 DFINRM---HNQIPQITCDGKRLQVIVCSATLHSFDVKKLSEKIMH 424
             I ++   H   P+      + Q ++ SAT    D+++L+   ++
Sbjct: 234 PEIRKLVDTHGMPPK-----TQRQTLMFSATFKE-DIQRLAGDFLN 353
>17544
          Length = 1047

 Score = 50.1 bits (118), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 20/43 (46%), Positives = 31/43 (72%)
 Frame = +2

Query: 25  PTDIQAESIPLILGGGDVLMAAETGSGKTGAFSIPVIQIVYET 67
           PT +Q  ++P++LG  D++  A+TGSGKT AF +P++  VYE 
Sbjct: 701 PTPVQKFALPIVLGKRDLMACAQTGSGKTAAFLLPILNQVYEN 829

 Score = 33.9 bits (76), Expect = 0.22,   Method: Compositional matrix adjust.
 Identities = 19/53 (35%), Positives = 28/53 (52%)
 Frame = +2

Query: 287 PKALIVEPSRELAEQTLNNVKQFKKYIDNPKLRELLIIGGVAARDQLSVLDNG 339
           P ALI+ P+RELA Q  +  ++F       +LR  ++ GG     Q+  LD G
Sbjct: 890 PIALILAPTRELASQIYDEARKFAY---RSRLRPCVVYGGADIGAQMRDLDKG 1039
>11160
          Length = 646

 Score = 48.9 bits (115), Expect = 7e-06,   Method: Compositional matrix adjust.
 Identities = 31/81 (38%), Positives = 45/81 (55%), Gaps = 7/81 (8%)
 Frame = -1

Query: 325 GGVAARDQLS-VLDNGVDIVVGTPGRLDDLVSTGK--LNLSQ----VRFLVLDEADGLLS 377
           GGV+    +S  + +G  I++ TPGRLDDL S  +   NL+     +  LVLDEAD LL 
Sbjct: 646 GGVSCSHDISKFMKSGGSILIATPGRLDDLFSRKESGFNLAASVKALEVLVLDEADRLLD 467

Query: 378 QGYSDFINRMHNQIPQITCDG 398
            G+   IN +   +P++   G
Sbjct: 466 MGFEASINTILGHLPKLRRTG 404
>10649
          Length = 472

 Score = 48.5 bits (114), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 30/87 (34%), Positives = 46/87 (52%), Gaps = 1/87 (1%)
 Frame = +1

Query: 540 FSCVCLHGDRKPHERKQNLER-FKKGDVRFLICTDVAARGIDIHGVPYVINVTLPDEKQN 598
            S + LHG   P  R+ ++ R F +     LI TD+A RG+D   V +VI +  P +   
Sbjct: 67  MSVLVLHGG-IPQLRRLDIYREFCRKQHVILITTDLACRGLDFPAVNWVIQLDCPVDVNT 243

Query: 599 YVHRIGRVGRAERMGLAISLVATEKEK 625
           Y+HR GR  R E  G A+ ++   +E+
Sbjct: 244 YIHRAGRTARFECNGQALLVLLPSEEE 324
>31220
          Length = 818

 Score = 45.8 bits (107), Expect = 7e-05,   Method: Compositional matrix adjust.
 Identities = 23/65 (35%), Positives = 32/65 (49%)
 Frame = +2

Query: 575 AARGIDIHGVPYVINVTLPDEKQNYVHRIGRVGRAERMGLAISLVATEKEKVWYHVCSNR 634
           A+RGID  GV  VIN   P +  +Y+HR GR  R    G  +S V+  KE         +
Sbjct: 161 ASRGIDFQGVNNVINFDFPLDVTSYIHRAGRTARGNNTGSVLSFVSV-KELPINQAVEEK 337

Query: 635 GKGCY 639
            + C+
Sbjct: 338 LRSCF 352
>12121
          Length = 465

 Score = 43.5 bits (101), Expect = 3e-04,   Method: Composition-based stats.
 Identities = 18/39 (46%), Positives = 26/39 (66%)
 Frame = -3

Query: 342 IVVGTPGRLDDLVSTGKLNLSQVRFLVLDEADGLLSQGY 380
           I + TPGRL D + + + NL +  +LVLDEAD +L  G+
Sbjct: 463 ICIATPGRLIDFLESNRTNLRRCTYLVLDEADRMLDMGF 347
>19172
          Length = 484

 Score = 42.7 bits (99), Expect = 5e-04,   Method: Composition-based stats.
 Identities = 29/93 (31%), Positives = 41/93 (44%)
 Frame = -1

Query: 487 EAIKILKGEYAVRAIKEHKMDQAIIFCRTKIDCDNLEQYFMQQGGGPDKKGHQFSCVCLH 546
           E+ KI K    +  I      + IIF  TK   D + +   +QG         +    +H
Sbjct: 394 ESEKIAKLIQLLTQISGENETKTIIFVETKKRVDEITRNISRQG---------WRACAIH 242

Query: 547 GDRKPHERKQNLERFKKGDVRFLICTDVAARGI 579
           GD+   ER   L  F+ G    L+ TDVAARG+
Sbjct: 241 GDKSQQERDFVLSSFRNGRHSILVATDVAARGL 143
>33083
          Length = 1931

 Score = 41.2 bits (95), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 19/48 (39%), Positives = 29/48 (60%), Gaps = 1/48 (2%)
 Frame = +1

Query: 577 RGIDIHGVPYVINVTLPDEKQNYVHRIGRVGRAE-RMGLAISLVATEK 623
           RG+DI  V +++    PDE + Y+HR+GR  R E   G A+ L+  E+
Sbjct: 1   RGLDIPQVDWIVQYDPPDESKEYIHRVGRTARGEGSSGKALLLLQPEE 144
>11423
          Length = 1434

 Score = 38.1 bits (87), Expect = 0.014,   Method: Compositional matrix adjust.
 Identities = 17/34 (50%), Positives = 22/34 (64%)
 Frame = -2

Query: 586  YVINVTLPDEKQNYVHRIGRVGRAERMGLAISLV 619
            YVI+   P   + Y+HR+GR  RA R G AISL+
Sbjct: 1394 YVISYDNPPYIKTYIHRVGRTARAGRAGTAISLL 1293
>06438
          Length = 989

 Score = 37.7 bits (86), Expect = 0.015,   Method: Compositional matrix adjust.
 Identities = 20/56 (35%), Positives = 31/56 (55%), Gaps = 1/56 (1%)
 Frame = +1

Query: 570 ICTDVAARGIDIHGVPYVINVTLPDEKQNYVHRIGRVGRAERMGLA-ISLVATEKE 624
           +   +A RG+D   V +VI +  P +   Y+HR GR  R E  G A + L+ +E+E
Sbjct: 25  LTVTLACRGLDFPAVNWVIQLDCPVDVNTYIHRAGRTARFECNGQALLVLLPSEEE 192
>30136
          Length = 524

 Score = 37.7 bits (86), Expect = 0.015,   Method: Composition-based stats.
 Identities = 18/58 (31%), Positives = 32/58 (55%)
 Frame = +2

Query: 4   FSEMGVMPEIAQAVEEMDWLLPTDIQAESIPLILGGGDVLMAAETGSGKTGAFSIPVI 61
           F+E  +   + + +    +  PT IQA+  P+ + G + +  A+TGSGKT  + +P I
Sbjct: 137 FAEAYLPDYVIKEIRRQGYKSPTPIQAQGWPIAMSGANFVGIAKTGSGKTLGYILPAI 310

 Score = 35.4 bits (80), Expect = 0.092,   Method: Composition-based stats.
 Identities = 23/76 (30%), Positives = 34/76 (44%)
 Frame = +2

Query: 271 HTGNAQVSQTKFLPNAPKALIVEPSRELAEQTLNNVKQFKKYIDNPKLRELLIIGGVAAR 330
           H  N Q  Q       P AL++ P+RELA+Q      +F     +  +R   + GG    
Sbjct: 314 HINNQQPLQRG---EGPIALVLAPTRELAQQIQQVATEFGS---SSYVRNTCVFGGAPKG 475

Query: 331 DQLSVLDNGVDIVVGT 346
            Q+  L  G +IV+ T
Sbjct: 476 GQMRDLQRGCEIVIAT 523
>31899
          Length = 453

 Score = 35.8 bits (81), Expect = 0.066,   Method: Compositional matrix adjust.
 Identities = 17/48 (35%), Positives = 31/48 (64%)
 Frame = -1

Query: 25  PTDIQAESIPLILGGGDVLMAAETGSGKTGAFSIPVIQIVYETLKDQQ 72
           P+ IQ ++IPL   G D+++ A++G+GKT  FS+  ++ +  T +  Q
Sbjct: 276 PSPIQLKAIPLGRCGLDLIVQAKSGTGKTCVFSVVALEGIETTARSTQ 133
>33543
          Length = 471

 Score = 34.7 bits (78), Expect = 0.16,   Method: Composition-based stats.
 Identities = 14/26 (53%), Positives = 18/26 (69%)
 Frame = +3

Query: 599 YVHRIGRVGRAERMGLAISLVATEKE 624
           Y+HR+GR GR    GLAI+ V+ E E
Sbjct: 6   YLHRVGRAGRFGTRGLAITFVSNETE 83
>03381
          Length = 1206

 Score = 34.3 bits (77), Expect = 0.21,   Method: Compositional matrix adjust.
 Identities = 22/83 (26%), Positives = 40/83 (48%), Gaps = 3/83 (3%)
 Frame = +3

Query: 579 IDIHGVPYVINVTLPDEKQNYVHRIGRVGRAERMGLAISLVATEKEKVWYHVCSNRGKGC 638
           +DI  +  V+N  +  +   + HR+GR GRA   G A +L+ T+K+K +  +     +G 
Sbjct: 3   LDIPHIRTVVNYDVARDIDTHTHRVGRTGRAGEKGSAYTLI-TDKDKEFAPLLVRNLEGA 179

Query: 639 YNT---RLKEDGGCTIWYNEMQL 658
             T    L +      W+N+ + 
Sbjct: 180 NQTPPPALLDLANQCPWFNKTRF 248
>34134
          Length = 271

 Score = 32.0 bits (71), Expect = 0.89,   Method: Composition-based stats.
 Identities = 13/29 (44%), Positives = 20/29 (68%)
 Frame = +3

Query: 33  IPLILGGGDVLMAAETGSGKTGAFSIPVI 61
           +P+ + G D +  A+TGSGKT +F +P I
Sbjct: 84  VPIAMSGRDCVGIAQTGSGKTLSFILPAI 170
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|54291704|ref|NP_694769.2| phosphofurin acidic cluster
sorting protein 1 [Mus musculus]
         (961 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

12294                                                                  79   9e-25
>12294
          Length = 454

 Score = 79.0 bits (193), Expect(2) = 9e-25,   Method: Compositional matrix adjust.
 Identities = 40/83 (48%), Positives = 60/83 (72%), Gaps = 5/83 (6%)
 Frame = +3

Query: 197 RYKNRTILGYKTLAVGLINMAEVMQHPNEGALVLGLHSNVKDVSVPVAEIKIYSLSSQPI 256
           +YKNRTILG+KTLA+G +NM++V+Q   +    L L+S+ K+   PVA++ ++ LSSQP+
Sbjct: 87  KYKNRTILGFKTLAIGHVNMSQVLQRSVDNR--LNLYSDAKERINPVAQLAVFGLSSQPV 260

Query: 257 DHE--GIKSKLS---DRSPDIDN 274
           DH+  G + + S   DRSPD+DN
Sbjct: 261 DHDDNGHRKQASSDVDRSPDVDN 329

 Score = 53.9 bits (128), Expect(2) = 9e-25,   Method: Composition-based stats.
 Identities = 23/31 (74%), Positives = 26/31 (83%)
 Frame = +1

Query: 169 LQLTFSLQYPHFLKRDANKLQIMLQRRKRYK 199
           L L+FSLQYPHFLKRD NK+ +MLQRRK  K
Sbjct: 4   LDLSFSLQYPHFLKRDGNKMLVMLQRRKNTK 96
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|110625717|ref|NP_081277.1| hypothetical protein
LOC69239 [Mus musculus]
         (1238 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

29521                                                                  59   2e-24
38751                                                                  52   1e-06
13952                                                                  40   0.004
03831                                                                  40   0.005
01502                                                                  39   0.015
02951                                                                  38   0.030
27925                                                                  36   0.10 
26948                                                                  33   0.55 
>29521
          Length = 903

 Score = 58.5 bits (140), Expect(3) = 2e-24,   Method: Compositional matrix adjust.
 Identities = 25/57 (43%), Positives = 34/57 (59%)
 Frame = +3

Query: 1105 VTVHNSSLPPLAIKHPECLGLLHQLERSTDVWIQHYCILKDGCLYFYASIRSTQASG 1161
            V+ HN  LP L ++ PEC G L ++      W + YCILKD CLY+Y ++ S  A G
Sbjct: 264  VSSHNVGLPALEVRRPECTGYLLKVGNRRRTWHRRYCILKDACLYYYKNMNSLSALG 434

 Score = 50.1 bits (118), Expect(3) = 2e-24,   Method: Compositional matrix adjust.
 Identities = 22/66 (33%), Positives = 36/66 (54%)
 Frame = +2

Query: 1157 TQASGGLYLQGYSVSEQTHGFEQPVIELKPSSEEFKTFYFCAENKTENQRWIAALKTSIK 1216
            +Q  G  +L GY V       ++    + P  +  +TF F AEN T+ QRW+ A+  SI+
Sbjct: 419  SQCFGVAHLHGYKVDPSISVGKKHAFGVVPPVDALRTFQFSAENDTDRQRWVDAMIRSIQ 598

Query: 1217 KWLPLD 1222
            +W+ +D
Sbjct: 599  RWIQID 616

 Score = 43.9 bits (102), Expect(3) = 2e-24,   Method: Composition-based stats.
 Identities = 26/80 (32%), Positives = 36/80 (45%)
 Frame = +1

Query: 1014 RWFVLKHDGFLLYYKHRKDEGKWPPLDMIKLEGAEVDIDNSLGKPFVFNCMPQSGSRILC 1073
            R+F+L+ D  L YYK R+D     PL  I L G         G+ F F    + G+R   
Sbjct: 1    RYFILRQDSCLYYYKQREDSD---PLGAIPLAGYTFSRHLDSGRDFCFKA-EKYGARTYY 168

Query: 1074 LCATSNQEMKRWLEAMQRAA 1093
                S  +M  W+ A+  AA
Sbjct: 169  FMTESRDDMTEWVGALSEAA 228

 Score = 38.9 bits (89), Expect = 0.012,   Method: Composition-based stats.
 Identities = 19/80 (23%), Positives = 35/80 (43%)
 Frame = +1

Query: 1138 QHYCILKDGCLYFYASIRSTQASGGLYLQGYSVSEQTHGFEQPVIELKPSSEEFKTFYFC 1197
            +++ + +D CLY+Y     +   G + L GY+ S             K      +T+YF 
Sbjct: 1    RYFILRQDSCLYYYKQREDSDPLGAIPLAGYTFSRHLDSGRD--FCFKAEKYGARTYYFM 174

Query: 1198 AENKTENQRWIAALKTSIKK 1217
             E++ +   W+ AL  +  K
Sbjct: 175  TESRDDMTEWVGALSEAAAK 234
>38751
          Length = 329

 Score = 52.4 bits (124), Expect = 1e-06,   Method: Composition-based stats.
 Identities = 25/69 (36%), Positives = 39/69 (56%)
 Frame = +3

Query: 922 QFSKPIVVTEVDTNSAAEEAGLQIGDVVLSVNGTEVTSVEHAEAVHLAKKGLDILTMVVA 981
           ++  PIVV  ++    AE+ GL IGD +L VNGT+ T + HAEAV + +   +++  V  
Sbjct: 24  EYGTPIVVYVIEEGCQAEQQGLNIGDRILDVNGTDFTHLTHAEAVTIMRNAWNVIMTV-- 197

Query: 982 SDISRCPNT 990
                CP +
Sbjct: 198 ---QPCPES 215
>13952
          Length = 577

 Score = 40.4 bits (93), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 34/142 (23%), Positives = 63/142 (44%), Gaps = 22/142 (15%)
 Frame = -3

Query: 993  PTCRGYLHKRTHSGFVKGWRKRWFVLKHDGFLLYYKHRKDEGKWPPLDMIKLEGAEV-DI 1051
            P   G+L K+   G  K W++RWF+L +D  L Y+++  D+    P  +I LE  +V ++
Sbjct: 422  PVKEGWLMKQ--GGRYKNWKRRWFIL-NDNCLYYFQYTADK---EPKGIIPLENIQVREL 261

Query: 1052 DNSLGKPFVFNCMPQSGSRILCLC-------------------ATSNQEMKRWLEAMQRA 1092
                 +   F     SGS ++  C                   A+S +EM  W+ +++  
Sbjct: 260  SEKSSRSNAFELYSVSGSDVIKACKVDSDGKVVEGRHSVYRMSASSAEEMDAWISSIRYG 81

Query: 1093 A--RPVHQNHVWEDVTVHNSSL 1112
                 +H++H + D     ++L
Sbjct: 80   I*EDQLHKSHNYFDYIQIQTTL 15
>03831
          Length = 1143

 Score = 40.4 bits (93), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 23/67 (34%), Positives = 35/67 (52%), Gaps = 3/67 (4%)
 Frame = +3

Query: 917 WGFRIQFSKPIV---VTEVDTNSAAEEAGLQIGDVVLSVNGTEVTSVEHAEAVHLAKKGL 973
           +GF +   K      + +VD  S AE AGL+ GD ++ VNGT + +  H + V   K G 
Sbjct: 171 YGFNLHAEKGKAGQFIGKVDEGSPAEAAGLKAGDRIVEVNGTNIGNENHQQVVGRIKAGG 350

Query: 974 DILTMVV 980
           D   ++V
Sbjct: 351 DETRLLV 371
>01502
          Length = 1949

 Score = 38.9 bits (89), Expect = 0.015,   Method: Composition-based stats.
 Identities = 25/66 (37%), Positives = 35/66 (53%)
 Frame = +1

Query: 915 YPWGFRIQFSKPIVVTEVDTNSAAEEAGLQIGDVVLSVNGTEVTSVEHAEAVHLAKKGLD 974
           YP    +   K I VT +  NS A   GLQ+ D +L +NG + T V H +AV   +K   
Sbjct: 1   YPDKIILYPDKGIYVTFIYENSPAARCGLQLHDKILQLNGKDFTVVTHKQAVENIRKK-P 177

Query: 975 ILTMVV 980
           +L M+V
Sbjct: 178 VLKMLV 195
>02951
          Length = 1076

 Score = 37.7 bits (86), Expect = 0.030,   Method: Composition-based stats.
 Identities = 23/56 (41%), Positives = 32/56 (57%)
 Frame = +2

Query: 925 KPIVVTEVDTNSAAEEAGLQIGDVVLSVNGTEVTSVEHAEAVHLAKKGLDILTMVV 980
           K I VT +  NS A   GLQ+ D +L +NG + T V H +AV   +K   +L M+V
Sbjct: 17  KGIYVTFIYENSPAARCGLQLHDKILQLNGKDFTVVTHKQAVENIRKK-PVLKMLV 181
>27925
          Length = 370

 Score = 35.8 bits (81), Expect = 0.10,   Method: Composition-based stats.
 Identities = 22/55 (40%), Positives = 27/55 (49%), Gaps = 2/55 (3%)
 Frame = +3

Query: 1009 KGWRKRWFVLKHDGFLLYYKHRKDEGKWPPLDMIK--LEGAEVDIDNSLGKPFVF 1061
            K W +RWF L+ D  L YYK   D      + M K  +E   +DI    GKPF F
Sbjct: 21   KKWVRRWFSLRPDNCLYYYKTEDDSQPVGAMIMAKHTVELCPIDI----GKPFGF 173
>26948
          Length = 2380

 Score = 33.5 bits (75), Expect = 0.55,   Method: Compositional matrix adjust.
 Identities = 10/34 (29%), Positives = 24/34 (70%)
 Frame = -2

Query: 917  WGFRIQFSKPIVVTEVDTNSAAEEAGLQIGDVVL 950
            +GF ++   P++V +++ +S A  +G+++GD V+
Sbjct: 1563 FGFSVRGDSPVIVADIELDSVAGRSGMKVGDFVV 1462
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|168480120|ref|NP_084444.3| RIKEN cDNA 4921505C17 [Mus
musculus]
         (1708 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

26300                                                                  71   2e-24
>26300
          Length = 452

 Score = 70.9 bits (172), Expect(2) = 2e-24,   Method: Composition-based stats.
 Identities = 32/66 (48%), Positives = 44/66 (66%)
 Frame = -1

Query: 134 DIQQSNEVERTQALRLVRKMITVNASLFPSSVANSLIAVGNDGLQERDRMVRACIAIICE 193
           D+   NE+ER  A+RL+R++  V     P S+  S+IAVGNDG  ERDR VR C+A +CE
Sbjct: 200 DVCLDNEIERVHAIRLIRQINAVAPKQMPLSLVYSIIAVGNDGASERDRFVRICLATLCE 21

Query: 194 LALQNP 199
           + L +P
Sbjct: 20  IMLCSP 3

 Score = 61.6 bits (148), Expect(2) = 2e-24,   Method: Composition-based stats.
 Identities = 29/57 (50%), Positives = 41/57 (71%)
 Frame = -3

Query: 77  LGFNYEDIIICLRLALLNEAKEVRAAGLRALRYLIQDSSILQKVLKLKVDYLIARCI 133
           LG +  +I+ CL++ LL+EAKEVRAA LR LR+L+Q   +L   L L +DYL+ RC+
Sbjct: 372 LGLSSVEILACLQIGLLHEAKEVRAAVLRVLRHLLQTEDMLHAFLALHMDYLVMRCL 202
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|171460960|ref|NP_083907.3| abhydrolase domain
containing 14b [Mus musculus]
         (210 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

01296                                                                  79   2e-24
25689                                                                  97   4e-21
36649                                                                  28   2.8  
05344                                                                  27   8.0  
>01296
          Length = 1409

 Score = 79.0 bits (193), Expect(2) = 2e-24,   Method: Compositional matrix adjust.
 Identities = 55/141 (39%), Positives = 73/141 (51%), Gaps = 5/141 (3%)
 Frame = +2

Query: 70  PGLGRSKXXXXXXXXXXXXXXSFLAAVVDTLELGPPVVISPSLSGMYSLPFLVAPGSQLR 129
           PG GRSK               F+ A+V ++   PPV+ISPS+SG +SLP+L    S+  
Sbjct: 311 PGYGRSKDVSLGKISNE----EFVTALVKSIG-APPVIISPSMSGGFSLPYLFTQPSERT 475

Query: 130 ----GFVPVAPICTDKINAVDYASVKTPALIVYGDQDP-MGSSSFQHLKQLPNHRVLVME 184
               GF+PVAP+ T K     YA    P LIVYG  D  +G  S   L+ LP   V  + 
Sbjct: 476 QLAVGFMPVAPVMTRKFRE-QYAKSSLPTLIVYGATDEVLGFGSRDDLQLLPRSTVAEIP 652

Query: 185 GAGHPCYLDKPDEWHKGLLDF 205
            AGH CY+++P  +H  L  F
Sbjct: 653 DAGHACYMNQPALFHNVLHYF 715

 Score = 49.7 bits (117), Expect(2) = 2e-24,   Method: Compositional matrix adjust.
 Identities = 28/57 (49%), Positives = 37/57 (64%)
 Frame = +1

Query: 10  TIKVQGQNLFFRETRPGSGQPVRFSVLLLHGIRFSSETWQNLGTLQRLAEAGYRAVA 66
           ++K Q   +F ++  P S  P + +VLLLHG RF+S  WQ + TLQ LA  GYRAVA
Sbjct: 139 SVKNQTIQIFSQQASP-STNP-KLTVLLLHGQRFTSSDWQGINTLQLLALWGYRAVA 303
>25689
          Length = 546

 Score = 97.1 bits (240), Expect = 4e-21,   Method: Compositional matrix adjust.
 Identities = 54/123 (43%), Positives = 73/123 (59%), Gaps = 5/123 (4%)
 Frame = +3

Query: 92  FLAAVVDTLELGPPVVISPSLSGMYSLPFLVAPG----SQLRGFVPVAPICTDKINAVDY 147
           FL+A++ TL   P V++SPS+SG +SLP+L         +  GFVP+AP  +  + A +Y
Sbjct: 39  FLSALIKTLATKP-VIVSPSMSGSFSLPYLFKEADAGLEKAAGFVPIAP-TSSSLFAANY 212

Query: 148 ASVKTPALIVYGDQDP-MGSSSFQHLKQLPNHRVLVMEGAGHPCYLDKPDEWHKGLLDFL 206
              K P L+VYG QD  +G  S +HLK LPN  + V+  AGH CYLD P  +H  L  FL
Sbjct: 213 PKSKIPTLVVYGAQDENLGKQSAEHLKALPNANMEVIANAGHACYLDXPQHFHSLLQHFL 392

Query: 207 QGL 209
             L
Sbjct: 393 DTL 401
>36649
          Length = 712

 Score = 28.1 bits (61), Expect = 2.8,   Method: Compositional matrix adjust.
 Identities = 11/20 (55%), Positives = 14/20 (70%)
 Frame = +3

Query: 113 SGMYSLPFLVAPGSQLRGFV 132
           + MYS+PF V PGS L G +
Sbjct: 264 TSMYSMPFTVVPGSSLSGLM 323
>05344
          Length = 1178

 Score = 26.6 bits (57), Expect = 8.0,   Method: Compositional matrix adjust.
 Identities = 21/52 (40%), Positives = 24/52 (46%), Gaps = 4/52 (7%)
 Frame = -2

Query: 28  GQPVRFSVLLLHGIRFSSETWQ-NLGTLQRLAE---AGYRAVAIDLPGLGRS 75
           G   R  +L LHG       WQ N G+  RL     A    +AIDLPG G S
Sbjct: 982 GSRNRQPILALHG-------WQDNCGSFDRLCPLLPADCSVLAIDLPGHGNS 848
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|7242138|ref|NP_038201.1| Na+/K+ -ATPase beta 2
subunit [Mus musculus]
         (290 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

06574                                                                 108   2e-24
07572                                                                  31   0.55 
33546                                                                  28   4.5  
>06574
          Length = 2012

 Score =  108 bits (270), Expect = 2e-24,   Method: Compositional matrix adjust.
 Identities = 85/300 (28%), Positives = 136/300 (45%), Gaps = 34/300 (11%)
 Frame = -3

Query: 20   FVWNPRTHQFMGRTGTSWAFILLFYLVFYGFLTAMFSLTMWVMLQTVSDHTPKYQDRLA- 78
            F+WN      +GR G SWA I  FYL++Y  L   F   + +  QTV +  PK     + 
Sbjct: 1836 FLWNSEEKTVLGRGGRSWAEIGFFYLIYYICLAGFFVGMLAIFYQTVDEKRPKLTGESSL 1657

Query: 79   ---TPGLMIRPKTENLDVIVNI-SDTESWGQHVQKLNKFLEPYNDSIQAQ--KNDVCRPG 132
                PG+  +P  +    +V    D +S+  HV+ ++K L+PY D+  A+  K  VC   
Sbjct: 1656 LKGNPGMGFQPIPDVEYTLVRFRRDPDSYKPHVKSISKILQPYLDAEVAEDKKGKVCSAT 1477

Query: 133  RYYEQPDNGVLNYPKRACQFNRTQLGDCSGIGDPTHYGYS-----TGQPCVFIKMNRVIN 187
               + P  G       AC+ +   L     I +   +GY+     +GQPCV +++N++ +
Sbjct: 1476 ---DLPGEG------EACRVDVASLTQSCNIDN--KFGYNETSTLSGQPCVLLRLNKIFD 1330

Query: 188  FY-----------AGANQSMN-----------VTCVGKRDEDAENLGHFVMFPANGSIDL 225
            +            +GA++ +            + CVG+   D +N+G    +P  G    
Sbjct: 1329 WMPEKYTKENIKNSGASEELQQKILDDPEMIYIDCVGENPADRDNIGPIQYYPEQG-FRH 1153

Query: 226  MYFPYYGKKFHVNYTQPLVAVKFLNVTPNVEVNVECRINAANIATDDERDKFAGRVAFKL 285
             Y+P+  +    +Y  PLV V+F     NV + VECR  A NI  D  R +  G V F+L
Sbjct: 1152 YYYPFTNQP---DYMSPLVFVQFTKPAENVALMVECRALAPNINYD--RTEKEGGVHFEL 988
>07572
          Length = 1496

 Score = 31.2 bits (69), Expect = 0.55,   Method: Compositional matrix adjust.
 Identities = 14/36 (38%), Positives = 20/36 (55%), Gaps = 2/36 (5%)
 Frame = +3

Query: 10   CGQVVEEWKEF--VWNPRTHQFMGRTGTSWAFILLF 43
            CG  +EEWK +    + +T  F+ RT T W  +L F
Sbjct: 1104 CGHSMEEWKNYNCFRDTKTFSFLNRTATFWNALLPF 1211
>33546
          Length = 735

 Score = 28.1 bits (61), Expect = 4.5,   Method: Compositional matrix adjust.
 Identities = 10/30 (33%), Positives = 17/30 (56%)
 Frame = +3

Query: 3   IQKEKKSCGQVVEEWKEFVWNPRTHQFMGR 32
           I+  K SCG+ V  W E +W P + + + +
Sbjct: 198 IRLIKTSCGRKVLSWHERIWEPISSELVAK 287
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|9790125|ref|NP_062728.1| transgelin 3 [Mus musculus]
         (199 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

03735                                                                 108   2e-24
04399                                                                  36   0.011
>03735
          Length = 2383

 Score =  108 bits (270), Expect = 2e-24,   Method: Compositional matrix adjust.
 Identities = 75/213 (35%), Positives = 105/213 (49%), Gaps = 17/213 (7%)
 Frame = +2

Query: 4   RGPSYGLSREVQEKIEQKYDADLENKLVDWIILQCAE-----DIEHPPPGRAHFQKWLMD 58
           R P  G +R+ Q KI+  +D D   K + WI     E     D ++      +F + L D
Sbjct: 215 RAPKAGSNRDAQNKIDASFDCDDAKKALYWIQAATGERVPITDSDNKAEVMNNFHQVLQD 394

Query: 59  GTVLCKLINSLYPPGQE---------PIPKISESKMAF---KQMEQISQFLKAAEVYGVR 106
           G +LCKL N+  PP Q+         P       K  F   ++ E+I  F    + +GV 
Sbjct: 395 GFLLCKLANAFLPPDQQFDMRTRTFRPPQNQDGLKSNFESARERERIDLFNMKIQDFGVS 574

Query: 107 TTDIFQTVDLWEGKDMAAVQRTLMALGSVAVTKDDGCYRGEPSWFHRKAQQNRRGFSEEQ 166
             D FQT  L+E  +++ V  T+   G     +    Y G+  W  RK++ N R FSEE+
Sbjct: 575 EQDTFQTDCLYERTNLSKVISTIRVFGITVEAQ--PSYTGQKIW-PRKSEANPRHFSEEK 745

Query: 167 LRQGQNVIGLQMGSNKGASQAGMTGYGMPRQIM 199
           LR  QNVI LQ G+NKGASQAGM  +G  R I+
Sbjct: 746 LRASQNVISLQYGTNKGASQAGM-NFGKKRMIL 841
>04399
          Length = 1562

 Score = 35.8 bits (81), Expect = 0.011,   Method: Compositional matrix adjust.
 Identities = 19/36 (52%), Positives = 24/36 (66%)
 Frame = -1

Query: 163  SEEQLRQGQNVIGLQMGSNKGASQAGMTGYGMPRQI 198
            +++  R+   VIGLQ GSNKGASQ GM+  G  R I
Sbjct: 1496 ADDASRESSGVIGLQAGSNKGASQXGMS-MGAVRHI 1392
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|13384710|ref|NP_080854.1| nucleolar protein family A,
member 1 [Mus musculus]
         (231 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

05434                                                                 107   3e-24
21002                                                                 102   2e-22
33190                                                                  77   7e-15
>05434
          Length = 1240

 Score =  107 bits (268), Expect = 3e-24,   Method: Compositional matrix adjust.
 Identities = 52/78 (66%), Positives = 62/78 (79%)
 Frame = +1

Query: 74  DQGPPERVVLLGEFMHPCEDDIVCKCTTEENKVPYFNAPVYLENKEQVGKVDEIFGQLRD 133
           D GPP  V  +G   H CEDD+VCK   EE K+PYFNA +YLENKEQVGKVDEIFG +RD
Sbjct: 577 DSGPPSYVEEIGFMTHTCEDDLVCKSVMEE-KIPYFNADIYLENKEQVGKVDEIFGGVRD 753

Query: 134 FYFSVKLSENMKASSFKK 151
           +YFSVKLS+++KA+SF K
Sbjct: 754 YYFSVKLSDSVKAASFSK 807
>21002
          Length = 391

 Score =  102 bits (253), Expect = 2e-22,   Method: Compositional matrix adjust.
 Identities = 49/76 (64%), Positives = 60/76 (78%)
 Frame = -2

Query: 72  FQDQGPPERVVLLGEFMHPCEDDIVCKCTTEENKVPYFNAPVYLENKEQVGKVDEIFGQL 131
           + D GPP  V  +G   H CEDD+VCK   EE K+PYFNA +YLENKEQVGKVDEIFG +
Sbjct: 318 YYDSGPPSYVEEIGFMTHTCEDDLVCKSVMEE-KIPYFNADIYLENKEQVGKVDEIFGGV 142

Query: 132 RDFYFSVKLSENMKAS 147
           RD+YFSVKLS+++KA+
Sbjct: 141 RDYYFSVKLSDSVKAA 94
>33190
          Length = 669

 Score = 76.6 bits (187), Expect = 7e-15,   Method: Compositional matrix adjust.
 Identities = 37/57 (64%), Positives = 43/57 (75%)
 Frame = -1

Query: 78  PERVVLLGEFMHPCEDDIVCKCTTEENKVPYFNAPVYLENKEQVGKVDEIFGQLRDF 134
           P  V  +G   H CEDD+VCK   EE K+PYFNA +YLENKEQVGKVDEIFG +RD+
Sbjct: 630 PSYVEEIGFMTHTCEDDLVCKSVMEE-KIPYFNADIYLENKEQVGKVDEIFGGVRDY 463
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31981237|ref|NP_073144.2| thimet oligopeptidase 1
[Mus musculus]
         (687 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

11707                                                                 109   3e-24
>11707
          Length = 863

 Score =  109 bits (273), Expect = 3e-24,   Method: Compositional matrix adjust.
 Identities = 77/277 (27%), Positives = 125/277 (45%), Gaps = 10/277 (3%)
 Frame = -3

Query: 408 IGKFYLDLYPREGKYGHAACFGLQPGCLRQDGSRQLAVAAMVANFTKPTPDAPSLLQHDE 467
           +G  Y D   R GK      F ++ G   + G  QL V  +  N   P  + P+LL    
Sbjct: 855 LGYIYCDSL-RAGKPNQDCHFTIRGGRQCEGGEYQLPVVVLQLNLPAPAGNTPTLLTPGM 679

Query: 468 VETYFHEFGHVMHQLCSQAEFAMFSGTHVERDFVEAPSQMLENWVWEKEPLMRMSQHYRT 527
           +E  FHEFGH MH +  + ++   +GT    DF E PS ++E +  +   +   ++HY+T
Sbjct: 678 MENLFHEFGHAMHSMLGRTKYQHVTGTRCSTDFAEVPSVLMEFFATDPRVISSFARHYKT 499

Query: 528 GSEAPQDLLEKLIKSRQANAGLFNLRQIVLAKVDQVLH----------TQTDADPAEEYA 577
           G    + +++ +  ++   A     +Q   + +DQV H          T   AD  + Y+
Sbjct: 498 GEPLSESVVQDMSAAKHLFAASDLQQQTFYSALDQVYHGPHPLPGXSTTSILADVQQXYS 319

Query: 578 RLCQEILGVPATPGTNMPATFGHLAGGYDAQYYGYLWSEVYSMDMFHTRFKQEGVLSPKV 637
            L       P    T     FGHL  GY A+YY YL S   +  ++HT F+ +   +  +
Sbjct: 318 CL-------PYVRDTAWQLRFGHLV-GYGARYYAYLISRAVAARLWHTCFRDD-PFNRAM 166

Query: 638 GMDYRTSILRPGGSEDASAMLKQFLGRDPKQDAFLLS 674
           G  YR  +L+ GG    + +++  LG  P  D  + S
Sbjct: 165 GQRYREEMLQHGGGIHPTVLVEGMLGEKPGVDNLVDS 55
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|8567402|ref|NP_038691.1| splicing factor,
arginine/serine-rich 3 (SRp20) [Mus musculus]
         (164 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

02347                                                                 107   3e-24
20169                                                                 102   1e-22
02809                                                                  91   2e-19
23720                                                                  61   2e-10
04988                                                                  61   3e-10
01065                                                                  55   1e-08
00738                                                                  55   2e-08
29364                                                                  52   8e-08
16427                                                                  50   3e-07
00029                                                                  50   3e-07
31310                                                                  50   6e-07
03059                                                                  49   7e-07
15503                                                                  41   2e-04
02140                                                                  39   8e-04
39789                                                                  39   0.001
17775                                                                  39   0.001
17681                                                                  37   0.004
11579                                                                  36   0.006
11687                                                                  35   0.017
12350                                                                  34   0.030
11126                                                                  34   0.033
12506                                                                  33   0.040
24794                                                                  33   0.075
25950                                                                  31   0.22 
00781                                                                  30   0.31 
08816                                                                  29   1.1  
17175                                                                  28   1.9  
08876                                                                  26   6.1  
12593                                                                  26   6.4  
>02347
          Length = 928

 Score =  107 bits (266), Expect = 3e-24,   Method: Compositional matrix adjust.
 Identities = 53/83 (63%), Positives = 63/83 (75%)
 Frame = -3

Query: 1   MHRDSCPLDCKVYVGNLGNNGNKTELERAFGYYGPLRSVWVARNPPGFAFVEFEDPRDAA 60
           M R    ++ K+YVG+L  + ++ E+ERAF YYG LR+VWVARNPPGFAFVEFED RDA 
Sbjct: 773 MSRYGSSVEGKIYVGDLPPDASEKEVERAFNYYGHLRNVWVARNPPGFAFVEFEDTRDAD 594

Query: 61  DAVRELDGRTLCGCRVRVELSNG 83
           DAVR LDG  +CG RVRVE S G
Sbjct: 593 DAVRALDGTVVCGNRVRVEHSTG 525
>20169
          Length = 1364

 Score =  102 bits (253), Expect = 1e-22,   Method: Compositional matrix adjust.
 Identities = 53/81 (65%), Positives = 59/81 (72%)
 Frame = -1

Query: 2    HRDSCPLDCKVYVGNLGNNGNKTELERAFGYYGPLRSVWVARNPPGFAFVEFEDPRDAAD 61
            HRD   LDCKVYVG LG+   K ELE  F  YGPL++VWVAR P GFAFVEFED RDA D
Sbjct: 1091 HRDFS-LDCKVYVGELGHGCAKQELEDKFAKYGPLKNVWVARRPAGFAFVEFEDNRDAED 915

Query: 62   AVRELDGRTLCGCRVRVELSN 82
            AV+ LDG  + G R RVE+SN
Sbjct: 914  AVQALDGARINGRRARVEMSN 852
>02809
          Length = 1475

 Score = 90.9 bits (224), Expect = 2e-19,   Method: Compositional matrix adjust.
 Identities = 46/67 (68%), Positives = 50/67 (74%)
 Frame = -1

Query: 2    HRDSCPLDCKVYVGNLGNNGNKTELERAFGYYGPLRSVWVARNPPGFAFVEFEDPRDAAD 61
            HRD   LDCKVYVG LG+   K ELE  F  YGPL++VWVAR P GFAFVEFED RDA D
Sbjct: 1355 HRDF-SLDCKVYVGELGHGCAKQELEDKFAKYGPLKNVWVARRPAGFAFVEFEDNRDAED 1179

Query: 62   AVRELDG 68
            AV+ LDG
Sbjct: 1178 AVQALDG 1158
>23720
          Length = 739

 Score = 60.8 bits (146), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 33/79 (41%), Positives = 47/79 (59%)
 Frame = -1

Query: 5   SCPLDCKVYVGNLGNNGNKTELERAFGYYGPLRSVWVARNPPGFAFVEFEDPRDAADAVR 64
           S  +  +VY+G L     + ++ER F  YG +  + +     G+ FVEFED RDA DAV 
Sbjct: 700 SNRMGTRVYIGRLPYQAREKDIERFFRGYGRVNDIML---KNGYGFVEFEDFRDADDAVY 530

Query: 65  ELDGRTLCGCRVRVELSNG 83
           EL+G+ LCG RV +E + G
Sbjct: 529 ELNGKDLCGERVIIEHARG 473
>04988
          Length = 705

 Score = 60.8 bits (146), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 33/79 (41%), Positives = 47/79 (59%)
 Frame = -3

Query: 5   SCPLDCKVYVGNLGNNGNKTELERAFGYYGPLRSVWVARNPPGFAFVEFEDPRDAADAVR 64
           S  +  +VY+G L     + ++ER F  YG +  + +     G+ FVEFED RDA DAV 
Sbjct: 667 SNRMGTRVYIGRLPYQAREKDIERFFRGYGRVNDIML---KNGYGFVEFEDFRDADDAVY 497

Query: 65  ELDGRTLCGCRVRVELSNG 83
           EL+G+ LCG RV +E + G
Sbjct: 496 ELNGKDLCGERVIIEHARG 440
>01065
          Length = 1033

 Score = 55.5 bits (132), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 24/74 (32%), Positives = 43/74 (58%)
 Frame = +2

Query: 8  LDCKVYVGNLGNNGNKTELERAFGYYGPLRSVWVARNPPGFAFVEFEDPRDAADAVRELD 67
          +  +++VG+L ++ +  E+   F  +G +  +W+ R  P  AFV +    DA  A+R +D
Sbjct: 8  VGTRIHVGSLSSSTSTREIREEFKRFGDIIDLWMPRTQPTIAFVVYRYEEDAEKAIRRMD 187

Query: 68 GRTLCGCRVRVELS 81
          G ++ G RVRV L+
Sbjct: 188GESMHGRRVRVSLA 229
>00738
          Length = 1559

 Score = 55.1 bits (131), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 24/74 (32%), Positives = 43/74 (58%)
 Frame = -2

Query: 8    LDCKVYVGNLGNNGNKTELERAFGYYGPLRSVWVARNPPGFAFVEFEDPRDAADAVRELD 67
            +  +++VG+L ++ +  E+   F  +G +  +W+ R  P  AFV +    DA  A+R +D
Sbjct: 1273 VGTRIHVGSLSSSTSTREIREEFKRFGDIIDLWMPRTQPTIAFVVYRYEEDAEKAIRRMD 1094

Query: 68   GRTLCGCRVRVELS 81
            G ++ G RVRV L+
Sbjct: 1093 GESMHGRRVRVSLA 1052
>29364
          Length = 1126

 Score = 52.4 bits (124), Expect = 8e-08,   Method: Compositional matrix adjust.
 Identities = 30/59 (50%), Positives = 37/59 (62%)
 Frame = +1

Query: 25 ELERAFGYYGPLRSVWVARNPPGFAFVEFEDPRDAADAVRELDGRTLCGCRVRVELSNG 83
          +LER F  YG  R + +     G+ FVEFED RDA DAV EL+G+ L G RV VE + G
Sbjct: 13 DLERFFKGYGRTRDILIKN---GYGFVEFEDYRDADDAVYELNGKELLGERVVVEPARG 180
>16427
          Length = 1313

 Score = 50.4 bits (119), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 26/74 (35%), Positives = 42/74 (56%), Gaps = 5/74 (6%)
 Frame = +1

Query: 11  KVYVGNLGNNGNKTELERAFGYYGPLRSVWVARNPP-----GFAFVEFEDPRDAADAVRE 65
           K++VG L    ++  LER F  +G +    V R+       GF FV +E+P DA +AV+ 
Sbjct: 139 KLFVGGLAEEIDEKVLEREFSKFGRITESMVIRDKVRQVSRGFGFVTYENPMDAEEAVKH 318

Query: 66  LDGRTLCGCRVRVE 79
           +DG+ + G ++ VE
Sbjct: 319 MDGKEILGKKLHVE 360
>00029
          Length = 2204

 Score = 50.4 bits (119), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 28/76 (36%), Positives = 42/76 (55%)
 Frame = -3

Query: 8    LDCKVYVGNLGNNGNKTELERAFGYYGPLRSVWVARNPPGFAFVEFEDPRDAADAVRELD 67
            +  K+++GNLG++ +  EL   F  YG +    V +N   F FV      +A DA+  L+
Sbjct: 2142 MTIKIFIGNLGDDTDPEELRALFEKYGSVAECDVLKN---FGFVHMVKKGEADDAISNLN 1972

Query: 68   GRTLCGCRVRVELSNG 83
            G  + G R+RVELS G
Sbjct: 1971 GYNIGGQRMRVELSTG 1924
>31310
          Length = 469

 Score = 49.7 bits (117), Expect = 6e-07,   Method: Compositional matrix adjust.
 Identities = 22/81 (27%), Positives = 49/81 (60%), Gaps = 5/81 (6%)
 Frame = -3

Query: 3   RDSCPLDCKVYVGNLGNNGNKTELERAFGYYGPLRSVWVARNP-----PGFAFVEFEDPR 57
           + +  L C++YVG++     +  +++AF  +GP++SV ++ +P      GF+F+E++ P 
Sbjct: 344 QQALALMCRIYVGSINFEIREDTIKQAFLPFGPIKSVNLSWDPITNKHKGFSFIEYDVPE 165

Query: 58  DAADAVRELDGRTLCGCRVRV 78
            A  A+ +++G  + G  ++V
Sbjct: 164 AAQLALEQMNGVMIGGRNIKV 102
>03059
          Length = 1154

 Score = 49.3 bits (116), Expect = 7e-07,   Method: Compositional matrix adjust.
 Identities = 25/77 (32%), Positives = 40/77 (51%), Gaps = 6/77 (7%)
 Frame = -2

Query: 6   CPLDCKVYVGNLGNNGNKTELERAFGYYGPLRSVWVARN------PPGFAFVEFEDPRDA 59
            P   KV+VG L  N NK  ++  F  YG ++ + +  +        G A+VE+E+P DA
Sbjct: 682 TPKPTKVHVGRLTRNVNKDHIQEIFSLYGTIKFIDLPNDRIHPNTSKGHAYVEYENPEDA 503

Query: 60  ADAVRELDGRTLCGCRV 76
             AV+ +DG  + G  +
Sbjct: 502 EKAVKYMDGGQIDGQEI 452
>15503
          Length = 570

 Score = 41.2 bits (95), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 24/63 (38%), Positives = 31/63 (49%), Gaps = 2/63 (3%)
 Frame = +1

Query: 12  VYVGNLGNNGNKTELERAFGYYGPLRSVWVARNP--PGFAFVEFEDPRDAADAVRELDGR 69
           +YV NL       E+   FG YG +R + V   P   G AFV +ED  DA +A   L G 
Sbjct: 154 LYVKNLPYKITAEEMYDIFGKYGAIRQIRVGNTPETKGTAFVVYEDIFDAKNACDHLSGF 333

Query: 70  TLC 72
            +C
Sbjct: 334 NVC 342
>02140
          Length = 1796

 Score = 39.3 bits (90), Expect = 8e-04,   Method: Compositional matrix adjust.
 Identities = 25/85 (29%), Positives = 39/85 (45%), Gaps = 5/85 (5%)
 Frame = +3

Query: 4   DSCPLDCKVYVGNLGNNGNKTELERAFGYYGPLRSVWVARNPPG-----FAFVEFEDPRD 58
           D+ P D  ++V  L       +LE  F  +GP+ S  V R+        +AFVEFE P  
Sbjct: 783 DTKPPDNVLFVCKLNPVTTDEDLEMIFSRFGPITSCEVIRDHKTKESLQYAFVEFEKPEH 962

Query: 59  AADAVRELDGRTLCGCRVRVELSNG 83
             +A  ++D   +   R+ V+ S  
Sbjct: 963 CENAYFKMDNVLIDDRRIHVDFSQS 1037
>39789
          Length = 361

 Score = 38.9 bits (89), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 24/66 (36%), Positives = 34/66 (51%), Gaps = 6/66 (9%)
 Frame = +1

Query: 12  VYVGNLGNNGNKTELERAF--GYYGPLRSVWVARNPPGFAFVEFEDPRDAADAV----RE 65
           ++VGNL  + ++  L+ AF       +      + P GF FVEF  P DAA A     RE
Sbjct: 94  LFVGNLSYDTDQYSLKDAFPGATAARIAKFQDTQKPRGFGFVEFSTPDDAASAFDSGERE 273

Query: 66  LDGRTL 71
           +DGR +
Sbjct: 274 VDGRQV 291
>17775
          Length = 1282

 Score = 38.5 bits (88), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 24/83 (28%), Positives = 41/83 (49%), Gaps = 5/83 (6%)
 Frame = -2

Query: 5    SCPLDCKVYVGNLGNNGNKTELERAFGYYGPLRSV-----WVARNPPGFAFVEFEDPRDA 59
            S P+   +YVG+L  +  +  L   F   GP+ S+      + R   G+A+V F+ P DA
Sbjct: 1206 SYPM-ASLYVGDLHPDVTEAMLFEKFSTAGPVLSIRVCRDMITRRSLGYAYVNFQQPADA 1030

Query: 60   ADAVRELDGRTLCGCRVRVELSN 82
              A+  ++  T+ G  +R+  S 
Sbjct: 1029 ERALDTMNFDTVKGRPIRIMWSQ 961
>17681
          Length = 964

 Score = 37.0 bits (84), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 19/76 (25%), Positives = 37/76 (48%), Gaps = 5/76 (6%)
 Frame = +2

Query: 12  VYVGNLGNNGNKTELERAFGYYGPLRSVWVARNPP-----GFAFVEFEDPRDAADAVREL 66
           ++VG+L        L  AF  +G + +  + R+P      G+AFV F    +A +A++ +
Sbjct: 38  IFVGDLSPEIETETLREAFAPFGEISNCRIVRDPQTMKSKGYAFVSFVKKAEAENAIQAM 217

Query: 67  DGRTLCGCRVRVELSN 82
           +G+ +    +R   S 
Sbjct: 218 NGQWIGSRSIRTNWST 265
>11579
          Length = 1307

 Score = 36.2 bits (82), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 18/35 (51%), Positives = 23/35 (65%)
 Frame = +3

Query: 47 GFAFVEFEDPRDAADAVRELDGRTLCGCRVRVELS 81
          GFAFV F D RDA DA+  +DG  L G  VR +++
Sbjct: 9  GFAFVRFYDRRDAEDAMDSMDGALLDGREVRCQMA 113
>11687
          Length = 676

 Score = 34.7 bits (78), Expect = 0.017,   Method: Compositional matrix adjust.
 Identities = 20/61 (32%), Positives = 31/61 (50%), Gaps = 5/61 (8%)
 Frame = +3

Query: 11  KVYVGNLGNNGNKTELERAFGYYGPLRSVWVARN-----PPGFAFVEFEDPRDAADAVRE 65
           K++VG +  N ++ EL + F  YGP+ S+ + R+       G  FV F   + A DA   
Sbjct: 153 KMFVGQIPRNMDENELRKMFEDYGPVHSLNILRDKNTGQSKGCCFVTFFTRKAALDAQNA 332

Query: 66  L 66
           L
Sbjct: 333 L 335
>12350
          Length = 975

 Score = 33.9 bits (76), Expect = 0.030,   Method: Compositional matrix adjust.
 Identities = 16/49 (32%), Positives = 26/49 (53%)
 Frame = -2

Query: 11  KVYVGNLGNNGNKTELERAFGYYGPLRSVWVARNPPGFAFVEFEDPRDA 59
           K++VG   ++    +L + F  +G +  V++ R    FAFV F DP  A
Sbjct: 359 KIFVGRCTDDMTADDLRQFFSKFGEVVDVFIPRPFRAFAFVSFADPEVA 213
>11126
          Length = 1061

 Score = 33.9 bits (76), Expect = 0.033,   Method: Compositional matrix adjust.
 Identities = 19/49 (38%), Positives = 26/49 (53%), Gaps = 5/49 (10%)
 Frame = -3

Query: 12  VYVGNLGNNGNKTELERAFGYYGPLRSVWV-----ARNPPGFAFVEFED 55
           VYVGN+       ELE+ F   G +  V +     + +P GFA+VEF D
Sbjct: 624 VYVGNVDYGATAEELEQHFHGCGSVNRVTILCDKYSGHPKGFAYVEFAD 478
>12506
          Length = 1056

 Score = 33.5 bits (75), Expect = 0.040,   Method: Compositional matrix adjust.
 Identities = 16/35 (45%), Positives = 22/35 (62%)
 Frame = -3

Query: 47  GFAFVEFEDPRDAADAVRELDGRTLCGCRVRVELS 81
           GFAF+EFE   DAA A+  ++   L G  +RV L+
Sbjct: 937 GFAFIEFELAEDAAAAIDNMNESELFGRTIRVNLA 833
>24794
          Length = 622

 Score = 32.7 bits (73), Expect = 0.075,   Method: Compositional matrix adjust.
 Identities = 15/36 (41%), Positives = 21/36 (58%)
 Frame = -2

Query: 46  PGFAFVEFEDPRDAADAVRELDGRTLCGCRVRVELS 81
           P   FV +    DA  A+R +DG ++ G RVRV L+
Sbjct: 501 PPLLFVVYRYEEDAEKAIRRMDGESMHGRRVRVSLA 394
>25950
          Length = 417

 Score = 31.2 bits (69), Expect = 0.22,   Method: Compositional matrix adjust.
 Identities = 18/47 (38%), Positives = 24/47 (51%), Gaps = 5/47 (10%)
 Frame = -2

Query: 12  VYVGNLGNNGNKTELERAFGYYGPLRSVWVARN-----PPGFAFVEF 53
           VYVGN+    +  ELE  F   G +  V +  N     P GFA++EF
Sbjct: 275 VYVGNVDYGASAEELEAHFHGCGTINRVTILCNKADGHPKGFAYIEF 135
>00781
          Length = 3170

 Score = 30.4 bits (67), Expect = 0.31,   Method: Compositional matrix adjust.
 Identities = 19/60 (31%), Positives = 28/60 (46%), Gaps = 5/60 (8%)
 Frame = -1

Query: 12   VYVGNLGNNGNKTELERAFGYYGPLRSVWV-----ARNPPGFAFVEFEDPRDAADAVREL 66
            VYV       ++  + R F   G +  V +      R   G+AFVEF+ P +A  AV+ L
Sbjct: 2714 VYVEGFHKFTSREWISRMFSKCGTVTYVSLPCFKTTREIKGYAFVEFQSPEEAVKAVQML 2535
>08816
          Length = 566

 Score = 28.9 bits (63), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 24/76 (31%), Positives = 33/76 (43%), Gaps = 3/76 (3%)
 Frame = +1

Query: 10  CKVYVGNLGNNGNKTELERAFGYYGPLRSVWVARN---PPGFAFVEFEDPRDAADAVREL 66
           C V V N+  +    EL   F   G ++   +  +   P G A V F    DA  A+  +
Sbjct: 49  CTVTVRNVPFSLTWQELRERFQDIGDVKFSEILMDQGRPSGDAVVRFGTSADAMRAINLV 228

Query: 67  DGRTLCGCRVRVELSN 82
           DG  + G  VRV L N
Sbjct: 229 DGTRIDGRTVRVVLRN 276
>17175
          Length = 512

 Score = 28.1 bits (61), Expect = 1.9,   Method: Compositional matrix adjust.
 Identities = 11/30 (36%), Positives = 19/30 (63%)
 Frame = -3

Query: 10 CKVYVGNLGNNGNKTELERAFGYYGPLRSV 39
           K++VG +  N ++ EL + F  YGP+ S+
Sbjct: 90 IKMFVGQIPRNMDENELRKMFEDYGPVHSL 1
>08876
          Length = 1026

 Score = 26.2 bits (56), Expect = 6.1,   Method: Compositional matrix adjust.
 Identities = 12/19 (63%), Positives = 15/19 (78%)
 Frame = +2

Query: 67 DGRTLCGCRVRVELSNGEK 85
          DG  + G RVRVELSNG++
Sbjct: 2  DGARINGGRVRVELSNGKR 58
>12593
          Length = 462

 Score = 26.2 bits (56), Expect = 6.4,   Method: Compositional matrix adjust.
 Identities = 10/17 (58%), Positives = 13/17 (76%)
 Frame = +2

Query: 47  GFAFVEFEDPRDAADAV 63
           GFA+VEFEDP    +A+
Sbjct: 128 GFAYVEFEDPDSLQEAL 178
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|158937308|ref|NP_835171.2| vacuolar protein sorting
33B [Mus musculus]
         (617 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

12886                                                                 108   4e-24
13186                                                                  42   0.001
02853                                                                  33   0.25 
30144                                                                  28   8.9  
>12886
          Length = 2104

 Score =  108 bits (271), Expect = 4e-24,   Method: Compositional matrix adjust.
 Identities = 87/305 (28%), Positives = 139/305 (45%), Gaps = 13/305 (4%)
 Frame = +1

Query: 322 QMKNFVSQELKGLKQEHRLLSLHIGACESIMKKKTKQDFQELIKTEHALLEGFNIRESTS 381
           +MK FVS+ L  L+   + L+ H    E + +     DF + ++ +   + G    +   
Sbjct: 1   EMKQFVSK-LPHLQASRQSLATHTSIAELVKEFTDTDDFIDALRCQQEFINGLETDKVHP 177

Query: 382 YIEEHIDRQVSPIESLRLMCLLSITENGLIPKDYRSLKTQYLQSYGPEHLLTFSNLRRAG 441
            IEE+I +  S  + LRL+C+ SI  +GL PK     + + LQ YG EH+LT   L + G
Sbjct: 178 LIEEYIAKSESLSKVLRLICIQSICNDGLKPKVLDFYRHEILQVYGFEHMLTLHYLEQVG 357

Query: 442 LLTEQAPGDTLTAVESKVSKLVTDKAAGKITDAFSSLAKRSNFRAISKKLNLIPRVDGEY 501
           LL                                       +++ + K L LI     E 
Sbjct: 358 LLRPHGA---------------------------------RSYQVLRKSLKLIVE---EV 429

Query: 502 DLKVPRDMAYVFSGAYVPLSCRIIEQVLDRRSWQGLDEVVRLLNCSEFAFTD-------- 553
           + + P D+AYV+SG Y PLS R + Q L R  W+ + EV+ LL                 
Sbjct: 430 NEQNPSDIAYVYSG-YAPLSVR-LAQYLARPGWRSITEVLNLLPGPRVEEVQQIPPALRK 603

Query: 554 ---TAKEDKASSESLRLILVVFLGGCTFSEISALRFLGREK--GYRFIFLTTAVTNSARL 608
              +    ++SS   +L LV FLGG TF+EI+ALRFL ++   G  ++  T+ + +  RL
Sbjct: 604 RRASITSTQSSSGEQKLTLVYFLGGVTFAEIAALRFLAQQDDGGTDYVVATSNLMSGHRL 783

Query: 609 MEAMS 613
           ++ ++
Sbjct: 784 LDCLT 798
>13186
          Length = 777

 Score = 41.6 bits (96), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 22/62 (35%), Positives = 38/62 (61%), Gaps = 7/62 (11%)
 Frame = -2

Query: 559 KASSESLRLILVVFLGGCTFSEISALRFLGRE-------KGYRFIFLTTAVTNSARLMEA 611
           ++SS   +L LV FLGG TF+EI+ALRFL ++        G  ++  T+ + +  RL++ 
Sbjct: 752 QSSSGEQKLTLVYFLGGVTFAEIAALRFLAQQDDEDCFSGGTDYVVATSNLMSGHRLLDC 573

Query: 612 MS 613
           ++
Sbjct: 572 LT 567
>02853
          Length = 1234

 Score = 33.5 bits (75), Expect = 0.25,   Method: Compositional matrix adjust.
 Identities = 17/57 (29%), Positives = 31/57 (54%)
 Frame = -3

Query: 174 NTVAQALHLLSTLYGPFPNCYGIGRCAKMSYDLWRKLEEEEDSETKGRKPEIGHIFL 230
           +T +++LH+ + L   +   +GIG   K+    W + EE E S   G+ P++ H+ L
Sbjct: 956 STXSRSLHIGNLLIAIYQAGWGIGEDKKLXKKRWGRGEERESSGA-GKAPDVLHVLL 789
>30144
          Length = 420

 Score = 28.5 bits (62), Expect = 8.9,   Method: Composition-based stats.
 Identities = 11/32 (34%), Positives = 20/32 (62%)
 Frame = +1

Query: 401 CLLSITENGLIPKDYRSLKTQYLQSYGPEHLL 432
           C++  T++G+   +YR+L T Y   Y  EH++
Sbjct: 304 CIIQNTKHGMQNSEYRTLTT*YRLYYNTEHII 399
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|13384756|ref|NP_079656.1| eukaryotic translation
elongation factor 1 epsilon 1 [Mus musculus]
         (174 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

17387                                                                 106   5e-24
10621                                                                  52   1e-07
20405                                                                  47   4e-06
28739                                                                  38   0.002
23211                                                                  35   0.012
11001                                                                  30   0.56 
01299                                                                  27   3.9  
02672                                                                  27   4.1  
34367                                                                  27   6.2  
>17387
          Length = 493

 Score =  106 bits (264), Expect = 5e-24,   Method: Compositional matrix adjust.
 Identities = 56/135 (41%), Positives = 83/135 (61%)
 Frame = +1

Query: 37  NGPSLMGLSTIATHLVKQASKEHLLGSTAEEKAMVQQWLEFRVTRVDGHSSKEDTQTLLK 96
           NG ++ G +T+A HL +  +    L  T E++A V QWLE+ VT++   S  +    +L+
Sbjct: 28  NGKTITGFTTVARHLSQAGNVPCDL--TLEQQAAVDQWLEYCVTQITHCSQAQHATHVLQ 201

Query: 97  DLNSYLEDKVYLAGHNITLADILLYYGLHRFIVDLTVQEKEKYLNVSRWFCHIQHYPDIR 156
           +LNSYL DKVY   H+ T+ADI++Y+GL      L   EKEKY+++SRWF +IQ    IR
Sbjct: 202 ELNSYLSDKVYFVTHHPTVADIVIYHGLFNVFTKLAYSEKEKYIHLSRWFDNIQQDQRIR 381

Query: 157 QHLSSIVFIKNRLYA 171
           Q L  + F +  LY+
Sbjct: 382 QSLQRLPFSRTALYS 426
>10621
          Length = 1304

 Score = 52.4 bits (124), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 38/149 (25%), Positives = 63/149 (42%), Gaps = 21/149 (14%)
 Frame = +2

Query: 29  QIPVLQTNNGPSLMGLSTIATHLVKQASKEHLLGSTAEEKAMVQQWLEF----------- 77
           ++P     NG +L   + IA ++      + L G TAE  A V QW++F           
Sbjct: 173 KVPAFSAKNGLNLSESNAIAQYV----GNKKLQGETAEAAAQVSQWIDFADNEILPSVCT 340

Query: 78  ---------RVTRVDGHSSKEDTQTLLKDLNSYLEDKVYLAGHNITLADILLYYGLHRFI 128
                    +  + +   +K      L  LN YL  + YL G ++T ADI L   L    
Sbjct: 341 WVFPCLGITQFNKQETERAKAQVTKALTVLNDYLLTRTYLVGESVTQADISLACNLIMLY 520

Query: 129 VDLTVQE-KEKYLNVSRWFCHIQHYPDIR 156
             +   E ++ + NV+RWF  + + P+ +
Sbjct: 521 EQVMDPEFRKPFQNVNRWFTTLVNQPNFK 607
>20405
          Length = 766

 Score = 47.0 bits (110), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 37/159 (23%), Positives = 67/159 (42%), Gaps = 21/159 (13%)
 Frame = -1

Query: 29  QIPVLQTNNGPSLMGLSTIATHLVKQASKEHLLGSTAEEKAMVQQWLEF----------- 77
           ++P  ++ +G  L+  S    + V  A+   L GS    +A + QW  +           
Sbjct: 619 KVPAYESADGKVLLTESNAIAYYVANAT---LRGSDVATQAAIYQWASWADSELLPASCA 449

Query: 78  ---------RVTRVDGHSSKEDTQTLLKDLNSYLEDKVYLAGHNITLADILLYYGL-HRF 127
                    +  + +   +K D    LK L+ +L  + +L    ITLADI+++  L H F
Sbjct: 448 WVFPYLGIMQFNKQNVERAKNDLLAALKVLDGHLLTRTFLVTERITLADIIVFTTLIHAF 269

Query: 128 IVDLTVQEKEKYLNVSRWFCHIQHYPDIRQHLSSIVFIK 166
              L    +   +NV RWF  + + P +   + +IV  +
Sbjct: 268 QNVLDASIRSSLVNVQRWFLTLANQPQVASVVGNIVLCE 152
>28739
          Length = 461

 Score = 38.1 bits (87), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 23/72 (31%), Positives = 33/72 (45%)
 Frame = -2

Query: 50  HLVKQASKEHLLGSTAEEKAMVQQWLEFRVTRVDGHSSKEDTQTLLKDLNSYLEDKVYLA 109
           +L +      L G T  EK  V  WL F   ++   S   D    L  L+S L+   +L 
Sbjct: 262 YLARAFPSAKLQGETILEKTEVDHWLNFAYGQL---SCASDFTVALDYLDSVLKPSTFLV 92

Query: 110 GHNITLADILLY 121
           GH +TLAD  ++
Sbjct: 91  GHALTLADFAVW 56
>23211
          Length = 1156

 Score = 35.4 bits (80), Expect = 0.012,   Method: Compositional matrix adjust.
 Identities = 20/60 (33%), Positives = 32/60 (53%), Gaps = 1/60 (1%)
 Frame = +1

Query: 98  LNSYLEDKVYLAGHNITLADILLYYGLHRFIVDLTVQE-KEKYLNVSRWFCHIQHYPDIR 156
           LN YL  + YL G ++T ADI L   L      +   E ++ + NV+RWF  + + P+ +
Sbjct: 10  LNDYLLTRTYLVGESVTQADISLACNLIMLYEQVMDPEFRKPFQNVNRWFXTLVNQPNFK 189
>11001
          Length = 752

 Score = 30.0 bits (66), Expect = 0.56,   Method: Compositional matrix adjust.
 Identities = 23/81 (28%), Positives = 33/81 (40%)
 Frame = -3

Query: 80  TRVDGHSSKEDTQTLLKDLNSYLEDKVYLAGHNITLADILLYYGLHRFIVDLTVQEKEKY 139
           TR  G  S + T  LL      L  K ++   N+  A   L +  H         EK + 
Sbjct: 618 TRSSGVISSDKTIGLLVFDQDALIVKFFVEARNVHTAWFRLIFSYHD------EPEKPEQ 457

Query: 140 LNVSRWFCHIQHYPDIRQHLS 160
            +   W C   ++PD RQHL+
Sbjct: 456 FSDGSWNCSGVNWPDFRQHLN 394
>01299
          Length = 1544

 Score = 26.9 bits (58), Expect = 3.9,   Method: Compositional matrix adjust.
 Identities = 10/24 (41%), Positives = 16/24 (66%)
 Frame = -1

Query: 136 KEKYLNVSRWFCHIQHYPDIRQHL 159
           + + +NV RW+C   H P I++HL
Sbjct: 80  RWRCMNVIRWYCLCLHNPVIKEHL 9
>02672
          Length = 2522

 Score = 26.9 bits (58), Expect = 4.1,   Method: Compositional matrix adjust.
 Identities = 12/32 (37%), Positives = 18/32 (56%)
 Frame = +3

Query: 143  SRWFCHIQHYPDIRQHLSSIVFIKNRLYANSH 174
            S + CH +H+PD R+    +  I NR  A+ H
Sbjct: 1884 SHFTCHTKHFPDGREDSVFLSNIFNRFEAHKH 1979
>34367
          Length = 905

 Score = 26.6 bits (57), Expect = 6.2,   Method: Compositional matrix adjust.
 Identities = 10/24 (41%), Positives = 14/24 (58%)
 Frame = -2

Query: 144 RWFCHIQHYPDIRQHLSSIVFIKN 167
           +WFCHIQH  ++    SS  F+  
Sbjct: 703 KWFCHIQHLFNMSTLYSSYEFLST 632
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|13385294|ref|NP_080099.1| prenylcysteine oxidase 1
[Mus musculus]
         (505 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

00636                                                                 108   5e-24
23441                                                                  79   4e-15
36257                                                                  73   3e-13
07940                                                                  33   0.34 
32695                                                                  28   5.9  
>00636
          Length = 1237

 Score =  108 bits (270), Expect = 5e-24,   Method: Compositional matrix adjust.
 Identities = 80/256 (31%), Positives = 123/256 (48%), Gaps = 12/256 (4%)
 Frame = +1

Query: 191 YVRLLNQTLRENLKKAGFSETFLNEMIAPVMKVNYGQSTDINAFVGAVSLTAADSNLWAV 250
           +V     +L   ++ AGFS+ F++E++   M+ NYGQ+   + FVG+V +   +  LWAV
Sbjct: 19  FVNYTRHSLTTIMRDAGFSDIFIDELVTGAMRENYGQTPQTHGFVGSVCMAGVEPGLWAV 198

Query: 251 EGGNKIVCSGLLQASSSNLISGSVMSIEEKTRTKQTGNPTKMYEVVY-------KTGSET 303
           +GGNK V   LL+AS + LI G+V  + +     ++   T  YEV Y       K   +T
Sbjct: 199 KGGNKNVPEKLLKASGAKLIRGTVTHVFQ----AKSDGGTVSYEVQYDKADVKGKDEDKT 366

Query: 304 HSDFYDIVLVAAPLNRKMS-NITFRNFDPPIEEFNDPYQQLVTTFIKGELNSTLFSSRPK 362
            S  YD++++A PL       I F +F   I+  + PY  L   F+ G  N + F     
Sbjct: 367 GSREYDLLIMATPLKSGSKLKIQFEDFPSQIQMPDIPYHTLDAMFVHGRPNVSFFGVDSV 546

Query: 363 DQFGLSAILVTDDSDMFINSLSIVASVRQKEGPPP---AVDGMHVWKTFSRDILTKEQIS 419
           + F   A+L+T D+D+  NS+     V +K   P       GM   K FS   L     S
Sbjct: 547 EDF--PALLMTTDTDVMFNSIGKQTPVVKKITWPENQMMWRGMQCGKLFSTKSLQNHS*S 720

Query: 420 K-LFLSYDYAVRKPWL 434
           + L ++  Y     WL
Sbjct: 721 RYLTVAKIYVWSTGWL 768

 Score = 95.1 bits (235), Expect = 6e-20,   Method: Compositional matrix adjust.
 Identities = 46/101 (45%), Positives = 63/101 (62%)
 Frame = +3

Query: 394 GPPPAVDGMHVWKTFSRDILTKEQISKLFLSYDYAVRKPWLSYPHYEPPQKCPSIILHDR 453
           G P  V+G  VWKTF   + ++ Q+ ++F S        WL+YP Y    + PS +LHDR
Sbjct: 642 GKPDDVEGYAVWKTFLNKVPSESQLKQIFDSRKDLRLVNWLAYPKYSANMELPSFVLHDR 821

Query: 454 LYYLNGIEFAASCMEMSAIAGYNAALLAYHRWNGNEDMIDQ 494
           LY++N IE AA+ MEMS I   N ALLAY++W G+ D ID+
Sbjct: 822 LYFINAIETAAAAMEMSVIGAKNVALLAYNQWFGHFDKIDE 944
>23441
          Length = 447

 Score = 79.0 bits (193), Expect = 4e-15,   Method: Compositional matrix adjust.
 Identities = 35/62 (56%), Positives = 45/62 (72%)
 Frame = +1

Query: 433 WLSYPHYEPPQKCPSIILHDRLYYLNGIEFAASCMEMSAIAGYNAALLAYHRWNGNEDMI 492
           WL+YP Y    + PS +LHDRLY++N IE AA+ MEMSAI   N ALLAY++W G+ D I
Sbjct: 64  WLAYPKYSANMELPSFVLHDRLYFINAIETAAAAMEMSAIGAKNVALLAYNQWFGHFDKI 243

Query: 493 DQ 494
           D+
Sbjct: 244 DE 249
>36257
          Length = 335

 Score = 72.8 bits (177), Expect = 3e-13,   Method: Compositional matrix adjust.
 Identities = 45/114 (39%), Positives = 59/114 (51%), Gaps = 2/114 (1%)
 Frame = -3

Query: 87  AGGSVIHPLNLHMKRFVKELGLSSVPASGG--LVGVYNGKSLVFEESSWFVINVIKLVWR 144
           AG   IHP N +M  F + LGLS      G  L  +     +V E S W  + V K  WR
Sbjct: 333 AGAPXIHPRNQYMVNFTRSLGLSEREREPGRRLGSLQ**GRIVLESSKWTTVTVAKXFWR 154

Query: 145 YGFQSLRMHMWVEDLLDKFMRIYRYQSHDYAFSSVEKLMHAIGGDDYVRLLNQT 198
           YG+   R+  WV D+L  F RIY YQ    +F++VE L+ A+  DD  R +N T
Sbjct: 153 YGWDMRRIVDWVGDMLQDFDRIYEYQHRGMSFTTVEDLLRAM--DD--RFVNYT 4
>07940
          Length = 1336

 Score = 32.7 bits (73), Expect = 0.34,   Method: Compositional matrix adjust.
 Identities = 24/77 (31%), Positives = 38/77 (49%)
 Frame = -1

Query: 242  AADSNLWAVEGGNKIVCSGLLQASSSNLISGSVMSIEEKTRTKQTGNPTKMYEVVYKTGS 301
            ++ ++LW  +GG +++C  LL   SS  + GS  S  E T ++   +P+ + E     G 
Sbjct: 1327 SSPTSLWRTQGGTRVLCPTLLV--SSMAVPGSPSSWTEPTSSR-VWDPSGVSE-----GP 1172

Query: 302  ETHSDFYDIVLVAAPLN 318
             T S      L AAPL 
Sbjct: 1171 ATTSSIKTHALSAAPLG 1121
>32695
          Length = 504

 Score = 28.5 bits (62), Expect = 5.9,   Method: Composition-based stats.
 Identities = 9/19 (47%), Positives = 14/19 (73%)
 Frame = +1

Query: 421 LFLSYDYAVRKPWLSYPHY 439
           LF+SY+  ++  WL +PHY
Sbjct: 223 LFISYNTLIKSLWLHFPHY 279
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31543942|ref|NP_033528.3| vinculin [Mus musculus]
         (1066 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

25886                                                                 109   5e-24
>25886
          Length = 419

 Score =  109 bits (273), Expect = 5e-24,   Method: Compositional matrix adjust.
 Identities = 52/122 (42%), Positives = 89/122 (72%), Gaps = 3/122 (2%)
 Frame = -3

Query: 428 RDDILRSLGEIAALTSKLGDLRRQGKGDSPEARALAKQVATALQNLQTKTNRAVANSRPA 487
           RD I++ +G+I ++++ L +LR+QGKG SP+A +LA+++ + L+ LQ +T  A+A++  +
Sbjct: 417 RDAIVKCVGDIESMSNALSELRQQGKGSSPQAMSLAREIQSKLRELQGQTANAIASTERS 238

Query: 488 ---KAAVHLEGKIEQAQRWIDNPTVDDRGVGQAAIRGLVAEGHRLANVMMGPYRQDLLAK 544
              K A  ++GK+EQA++W+ NP +DD+G+G++A R +V EG R+A+   GP RQ+LL  
Sbjct: 237 GIRKPAPTVDGKVEQARQWLANPGLDDKGLGESATRLVVDEGRRVASCCTGPQRQELLRL 58

Query: 545 CD 546
           CD
Sbjct: 57  CD 52

 Score = 61.2 bits (147), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 35/107 (32%), Positives = 58/107 (54%)
 Frame = -3

Query: 237 MSAEINEIIRVLQLTSWDEDAWASKDTEAMKRALASIDSKLNQAKGWLRDPNASPGDAGE 296
           ++ EI   +R LQ      +A AS +   +++   ++D K+ QA+ WL +P       GE
Sbjct: 315 LAREIQSKLRELQ--GQTANAIASTERSGIRKPAPTVDGKVEQARQWLANPGLDDKGLGE 142

Query: 297 QAIRQILDEAGKVGELCAGKERREILGTCKMLGQMTDQVADLRARGQ 343
            A R ++DE  +V   C G +R+E+L  C     +T+Q++DL  RGQ
Sbjct: 141 SATRLVVDEGRRVASCCTGPQRQELLRLCDETEILTNQLSDLCRRGQ 1

 Score = 29.6 bits (65), Expect = 6.0,   Method: Compositional matrix adjust.
 Identities = 13/30 (43%), Positives = 21/30 (70%)
 Frame = -3

Query: 562 GEGESPQARALASQLQDSLKDLKAQMQEAM 591
           G+G SPQA +LA ++Q  L++L+ Q   A+
Sbjct: 345 GKGSSPQAMSLAREIQSKLRELQGQTANAI 256
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|21313614|ref|NP_079621.1| hypothetical protein
LOC66086 [Mus musculus]
         (174 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

15210                                                                 106   6e-24
31034                                                                  29   0.95 
20111                                                                  28   1.6  
>15210
          Length = 729

 Score =  106 bits (264), Expect = 6e-24,   Method: Compositional matrix adjust.
 Identities = 51/89 (57%), Positives = 68/89 (76%)
 Frame = +3

Query: 31  EVFNALDDDREPRPSLSHENLLINELIREYLEFNKYKYTASVLIAESGQPVVPLDRQFLI 90
           EV++A+D   + RP +S+EN+LINELIREYLEFNKY+YT+SVL AESG    PLDR+FL 
Sbjct: 3   EVYSAIDRPADNRPVVSNENILINELIREYLEFNKYQYTSSVLQAESGMAKEPLDREFLR 182

Query: 91  RELNAFEESKDNSIPLLYGILAHFLRGPP 119
            ELN  E++   S+PLLY I++H+ +  P
Sbjct: 183 TELNVVEDAPSRSVPLLYSIVSHYTQKGP 269
>31034
          Length = 397

 Score = 29.3 bits (64), Expect = 0.95,   Method: Compositional matrix adjust.
 Identities = 13/34 (38%), Positives = 18/34 (52%)
 Frame = -2

Query: 51  LLINELIREYLEFNKYKYTASVLIAESGQPVVPL 84
           LL   LI  YL+   +K T ++ +  SGQ V  L
Sbjct: 240 LLCTTLISAYLQLAGFKTTINITLTHSGQSVFSL 139
>20111
          Length = 1004

 Score = 28.5 bits (62), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 17/40 (42%), Positives = 19/40 (47%), Gaps = 2/40 (5%)
 Frame = +2

Query: 114 FLRGPPDGA--QNVLLTESTLHPATKHLSWKPSRRPDDDH 151
           F R P  GA  QN  LT   L  A   L W+  RR + DH
Sbjct: 428 FRRLPWRGAACQNSCLTAGLLLAAPSLLDWRQGRRAESDH 547
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|41351529|ref|NP_958808.1| phosphatidylinositol glycan
anchor biosynthesis, class S [Mus musculus]
         (555 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

30063                                                                  83   9e-24
07370                                                                  32   0.74 
>30063
          Length = 642

 Score = 82.8 bits (203), Expect(2) = 9e-24,   Method: Compositional matrix adjust.
 Identities = 44/104 (42%), Positives = 69/104 (66%)
 Frame = +2

Query: 251 VQRFVQPFLNRLSVAGNFSVDSQILYYAMLGVNPRFDPASSSYSLAMHSLPHVINPVESR 310
           V+ +++PF+ +++     SV SQ+L++  L    R D +S SY      LPH+INP+E++
Sbjct: 2   VEGYLKPFMRKVADFVTISVTSQVLHFVGLVAPARKDSSSKSYFYTEQDLPHLINPLEAK 181

Query: 311 LGSSAASLYPVLHFLLYVPELAHSPLYIQDKDGAPVATNAFHSP 354
           LGS A++  P L+F++YVP  A SPLY++D +   VA+NAF SP
Sbjct: 182 LGSHASN-KPALNFVVYVPAKASSPLYLRDSNXDAVASNAFLSP 310

 Score = 45.8 bits (107), Expect(2) = 9e-24,   Method: Compositional matrix adjust.
 Identities = 38/112 (33%), Positives = 47/112 (41%), Gaps = 3/112 (2%)
 Frame = +3

Query: 357 GGIMVYNVD-PKIYNASELPXXXXXXXXXXXXXFLAQLRLLFGI-AQPQVPPKCL-LSGP 413
           G IM+YN + P   N++ LP             FL QLRLL  +  Q Q   K +  S  
Sbjct: 315 GWIMIYNAEIPS--NSTALPTINVDMKRMMEV-FLTQLRLLLNMHVQVQTSNKQVSFSDL 485

Query: 414 KSEGLMTWELDRLLWARSVENXXXXXXXXXXXXXXXGKISNIVIKDDVASEV 465
             + L  WEL   L  R VEN                +I NIVI DD+  EV
Sbjct: 486 GKDALTEWELAGWLRCRCVENLATAKASLQSLAQLLDQIGNIVINDDIGREV 641
>07370
          Length = 3144

 Score = 32.0 bits (71), Expect = 0.74,   Method: Compositional matrix adjust.
 Identities = 14/46 (30%), Positives = 25/46 (54%)
 Frame = -2

Query: 308  ESRLGSSAASLYPVLHFLLYVPELAHSPLYIQDKDGAPVATNAFHS 353
             +RL S   +  P+ H ++ +   AH+ +YIQ+    P+   AFH+
Sbjct: 2843 HNRLQSQTCTYIPIFHKVMCMQTHAHTHIYIQE-S*TPIHIRAFHT 2709
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31981041|ref|NP_062760.2| TANK-binding kinase 1 [Mus
musculus]
         (729 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

00300                                                                 107   1e-23
13592                                                                 100   2e-21
18921                                                                  84   2e-16
01707                                                                  81   1e-15
01756                                                                  79   8e-15
14126                                                                  76   5e-14
14420                                                                  75   1e-13
15910                                                                  73   3e-13
31885                                                                  73   4e-13
19301                                                                  68   2e-11
21079                                                                  67   2e-11
12721                                                                  65   7e-11
00392                                                                  65   9e-11
09606                                                                  65   1e-10
12786                                                                  59   7e-09
17253                                                                  58   1e-08
04591                                                                  58   1e-08
03240                                                                  57   2e-08
06405                                                                  57   3e-08
30755                                                                  55   1e-07
01392                                                                  55   1e-07
09007                                                                  54   2e-07
01060                                                                  54   2e-07
26711                                                                  54   3e-07
19761                                                                  53   3e-07
21808                                                                  52   8e-07
13212                                                                  52   1e-06
19094                                                                  51   2e-06
29581                                                                  50   3e-06
18484                                                                  50   3e-06
17975                                                                  49   5e-06
26560                                                                  49   9e-06
01966                                                                  42   2e-05
28157                                                                  47   2e-05
11780                                                                  45   7e-05
13066                                                                  44   3e-04
21433                                                                  43   5e-04
32359                                                                  36   8e-04
03508                                                                  42   8e-04
27274                                                                  42   0.001
27405                                                                  41   0.002
37602                                                                  41   0.002
07833                                                                  40   0.004
27546                                                                  39   0.008
12672                                                                  38   0.011
28638                                                                  38   0.012
11185                                                                  37   0.022
00486                                                                  37   0.031
29360                                                                  37   0.033
21800                                                                  37   0.042
07940                                                                  36   0.051
07836                                                                  35   0.080
36481                                                                  35   0.15 
01106                                                                  34   0.20 
32957                                                                  33   0.34 
18481                                                                  33   0.53 
16708                                                                  32   0.66 
00715                                                                  32   0.88 
21210                                                                  31   1.4  
18996                                                                  31   1.5  
26156                                                                  31   1.7  
15741                                                                  31   1.9  
31489                                                                  30   2.6  
26009                                                                  30   4.4  
38560                                                                  29   5.5  
16350                                                                  29   6.3  
>00300
          Length = 2318

 Score =  107 bits (268), Expect = 1e-23,   Method: Compositional matrix adjust.
 Identities = 77/248 (31%), Positives = 121/248 (48%), Gaps = 10/248 (4%)
 Frame = -1

Query: 6    NHLWLLSDILGQGATANVFRGRHKKTGDLYAVKVFNNISFLRPVDVQM-----REFEVLK 60
            N  W   + +G+G    V+   +  TG+L A+K        +P D+Q       E ++ +
Sbjct: 1661 NFRWQRGNKIGEGQFGKVYTAVNMSTGELMALKEMK----FQPNDLQQLREMCDEIKIFE 1494

Query: 61   KLNHKNIVKLFAIEEETTTRHKVLIMEFCPCGSLYTVLEEPSNAYGLPESEFLIVLRDVV 120
             + H+N+VK + +E        ++ ME+C  G++     E +   GLPE       R++V
Sbjct: 1493 GIQHENLVKYYGVE--VHKDEMLMFMEYCDTGTI-----EEAAKMGLPEYLIRRYTREIV 1335

Query: 121  GGMNHLRENGIVHRDIKPGNIMRVIGEDGQSVYKLTDFGAARELEDDE----QFVSLYGT 176
              +NHL EN IVHRDIK  NI   +  +G    KL DFG + +L+       +F +L GT
Sbjct: 1334 LAVNHLHENSIVHRDIKGANIF--LTSNGH--VKLGDFGCSVKLKSHTTMPGEFHNLVGT 1167

Query: 177  EEYLHPDMYERAVLRKDHQKKYGATVDLWSVGVTFYHAATGSLPFRPFEGPRRNKEVMYK 236
              Y+ P+     V  ++ Q  YG   D+WS+G      ATG    RP+     N ++MYK
Sbjct: 1166 TAYMAPE-----VFTQNDQGGYGRAADIWSLGCVVIEMATGK---RPWHDLDNNYQIMYK 1011

Query: 237  IITG-KPS 243
            +  G KP+
Sbjct: 1010 VGIGHKPA 987
>13592
          Length = 980

 Score =  100 bits (250), Expect = 2e-21,   Method: Compositional matrix adjust.
 Identities = 74/235 (31%), Positives = 119/235 (50%), Gaps = 7/235 (2%)
 Frame = +2

Query: 15  LGQGATANVFRGRHKKTGDLYAVK-VFNNISFLRPVDVQMREFEVLKKLNHKNIVKLFAI 73
           +GQG    V+   +  TG+L A+K +       R +     E ++L+ + HKN+V+ + I
Sbjct: 8   IGQGRFGKVYTAVNNNTGELMAMKEIAIQPGETRALKNVAEELKILEGIKHKNLVRYYGI 187

Query: 74  EEETTTRHKVLI-MEFCPCGSLYTVLEEPSNAYGLPESEFLIVLRDVVGGMNHLRENGIV 132
           E     R ++LI ME C  G+L +++E      GLPE+        ++ G+  L ++GIV
Sbjct: 188 E---VHREELLIFMELCSEGTLESLVELTG---GLPEALSRRFTAQLLSGVAELHKHGIV 349

Query: 133 HRDIKPGNIMRVIGEDGQSVYKLTDFGAARELEDDE----QFVSLYGTEEYLHPDMYERA 188
           HRDIK  NI  V   DG +  KL DFG+A +++       +     GT+ Y+ P+     
Sbjct: 350 HRDIKTANIFLV---DGSNSLKLGDFGSAVKIQAHTTVPGELQGYVGTQAYMAPE----- 505

Query: 189 VLRKDHQKKYGATVDLWSVGVTFYHAATGSLPFRPFEGPRRNKEVMYKIITG-KP 242
           V  K +   +G   D+WSVG      A+G  P+  F+    N ++M+K+  G KP
Sbjct: 506 VFTKTNSDGHGRLADIWSVGCVVVEMASGKRPWAQFD---SNFQIMFKVGMGEKP 661
>18921
          Length = 697

 Score = 83.6 bits (205), Expect = 2e-16,   Method: Compositional matrix adjust.
 Identities = 60/211 (28%), Positives = 105/211 (49%), Gaps = 5/211 (2%)
 Frame = +2

Query: 15  LGQGATANVFRGRHKKTGDLYAVKVFNNISFLRPVDVQM----REFEVLKKLNHKNIVKL 70
           LG+G+  +VF+  HK+TG + A+K         PVD  +    +E  ++++ + K IVK 
Sbjct: 53  LGEGSYGSVFKSLHKETGQVLAIKQV-------PVDTDLQEIIKEISIMQQCDSKYIVKY 211

Query: 71  FAIEEETTTRHKVLIMEFCPCGSLYTVLEEPSNAYGLPESEFLIVLRDVVGGMNHLRENG 130
           +    + T     ++ME+C  GS+  ++   +    L E E   +L   + G+ +L    
Sbjct: 212 YGSYFKNTDLW--IVMEYCGAGSVSDIMRLRNKT--LVEREIATILYYTLKGLXYLHSRR 379

Query: 131 IVHRDIKPGNIMRVIGEDGQSVYKLTDFGAARELEDD-EQFVSLYGTEEYLHPDMYERAV 189
            +HRDIK GNI+  +  +G +  KL DFG A +L D   +  ++ GT  ++ P++ +   
Sbjct: 380 KIHRDIKAGNIL--LNNEGHA--KLADFGVAGQLTDTMAKRNTVIGTPYWMAPEVIQ--- 538

Query: 190 LRKDHQKKYGATVDLWSVGVTFYHAATGSLP 220
                +  Y    D+WS+G+T    A G  P
Sbjct: 539 -----EIGYDCVADIWSLGITALEMAEGKPP 616
>01707
          Length = 757

 Score = 81.3 bits (199), Expect = 1e-15,   Method: Compositional matrix adjust.
 Identities = 66/208 (31%), Positives = 101/208 (48%), Gaps = 4/208 (1%)
 Frame = +1

Query: 15  LGQGATANVFRGRHKKTGDLYAVKVFNNISFLRPV--DVQMREFEVLKKLNHKNIVKLFA 72
           +G+G+   VF+ R+K+T  L A+K F   S   P+   + MRE  +LK+L H N+V+L  
Sbjct: 88  IGEGSYGVVFKCRNKETSQLVAIKKFVE-SEDDPLIKKIAMREIRMLKQLKHPNLVRLIE 264

Query: 73  IEEETTTRHKVLIMEFCPCGSLYTVLEEPSN-AYGLPESEFLIVLRDVVGGMNHLRENGI 131
           +       H  L+ ++      +T+L E      GLPE     ++   +  +N   +   
Sbjct: 265 VFRRKKRLH--LVFDYVD----HTLLNELDRYPRGLPEPMVKRIIYQTLLAVNFCHQYNT 426

Query: 132 VHRDIKPGNIMRVIGEDGQSVYKLTDFGAARELE-DDEQFVSLYGTEEYLHPDMYERAVL 190
           +HRD+KP NI+  I   GQ   KL DFG AR L    +++     T  Y  P++     L
Sbjct: 427 IHRDVKPENIL--ITRQGQV--KLCDFGFARILTGPGDEYTDYVATRWYRAPEL-----L 579

Query: 191 RKDHQKKYGATVDLWSVGVTFYHAATGS 218
             D Q  YG  VD+W++G  F    TG 
Sbjct: 580 VGDTQ--YGPPVDVWAIGCVFAELLTGQ 657
>01756
          Length = 1858

 Score = 78.6 bits (192), Expect = 8e-15,   Method: Compositional matrix adjust.
 Identities = 64/206 (31%), Positives = 101/206 (49%), Gaps = 12/206 (5%)
 Frame = -3

Query: 15   LGQGATANVFRGRHKKTGDLYAVK--VFNNISFLRPVDVQMREFEVLKKLNHKNIVKLFA 72
            +GQG    VF+ R KKT  + A+K  + +N     P+   +RE ++L+ LNH+N+V L  
Sbjct: 1718 IGQGTFGEVFKARCKKTKQVVAMKKVLMDNEKEGFPITA-LREIKILQLLNHENVVDLIE 1542

Query: 73   I---EEETTTRHK---VLIMEFCPCGSLYTVLEEPSNAYGLPESEFLIVLRDVVGGMNHL 126
            I   +  +  R+K    L+ EFC    L  +L   S  + LPE +   V++ ++ G+ ++
Sbjct: 1541 ICSTKATSANRYKSMFYLVFEFCE-HDLAGLLSNMSVVFNLPEIK--EVMKQLMNGLYYI 1371

Query: 127  RENGIVHRDIKPGNIMRVIGEDGQSVYKLTDFGAAR----ELEDDEQFVSLYGTEEYLHP 182
              N I+HRD+K  NI+       Q V KL DFG AR     L    ++ +   T  Y  P
Sbjct: 1370 HRNKILHRDMKAANILIT----KQGVLKLADFGLARAFSVNLRQPNRYTNRVVTLWYRPP 1203

Query: 183  DMYERAVLRKDHQKKYGATVDLWSVG 208
            ++     L  D  + Y   +D W  G
Sbjct: 1202 EL-----LLGD--RNYSTAIDQWGAG 1146
>14126
          Length = 1265

 Score = 75.9 bits (185), Expect = 5e-14,   Method: Compositional matrix adjust.
 Identities = 61/207 (29%), Positives = 101/207 (48%), Gaps = 9/207 (4%)
 Frame = +3

Query: 14  ILGQGATANVFRGRH-KKTGDLYAVKV--FNNISFLRPVDVQMREFEVLKKLN---HKNI 67
           ++G GA   V++ R  +  G+  A+K    NN     P+ + +RE  +LK+L    H N+
Sbjct: 210 VIGNGAYGTVYKARDLRNQGEFVAMKRIRLNNTEEGMPM-MAIREISMLKQLEQYEHPNV 386

Query: 68  VKLFAIEEETTTRHKV---LIMEFCPCGSLYTVLEEPSNAYGLPESEFLIVLRDVVGGMN 124
           V+L  +   T T  ++   L+ E+        + + PS   G    + L++   ++ G++
Sbjct: 387 VRLLDVSHNTITDREIRLNLVFEYIEHDLATYLAKCPSPGLGPDRIKDLML--QLLNGVD 560

Query: 125 HLRENGIVHRDIKPGNIMRVIGEDGQSVYKLTDFGAARELEDDEQFVSLYGTEEYLHPDM 184
            L  N IVHRD+KP N++  I +DG+   KL DFG AR         ++  T  Y  P++
Sbjct: 561 FLHSNRIVHRDLKPQNLL--ISKDGR--LKLADFGLARIYSFHMALTTVVVTLWYRSPEV 728

Query: 185 YERAVLRKDHQKKYGATVDLWSVGVTF 211
                     Q +YG +VD+WS G  F
Sbjct: 729 L--------MQAEYGTSVDIWSCGCIF 785
>14420
          Length = 528

 Score = 74.7 bits (182), Expect = 1e-13,   Method: Compositional matrix adjust.
 Identities = 52/170 (30%), Positives = 85/170 (50%), Gaps = 1/170 (0%)
 Frame = +2

Query: 53  MREFEVLKKLNHKNIVKLFAIEEETTTRHKVLIMEFCPCGSLYTVLEEPSNAYGLPESEF 112
           + E  V+++  + NIV    ++         ++MEF   GSL  V+ E      + E + 
Sbjct: 44  INEILVMRENQNPNIVNY--LDSYLVGEELWVVMEFLAGGSLTDVVTETC----MDEGQI 205

Query: 113 LIVLRDVVGGMNHLRENGIVHRDIKPGNIMRVIGEDGQSVYKLTDFGAARELEDDE-QFV 171
             V R+ +  +  L EN ++HRDIK  NI+  +G DG    KLTDFG   +L  ++ +  
Sbjct: 206 AAVCRECLQALEFLHENQVIHRDIKSDNIL--LGMDGS--VKLTDFGFCAQLSPEQSKRS 373

Query: 172 SLYGTEEYLHPDMYERAVLRKDHQKKYGATVDLWSVGVTFYHAATGSLPF 221
           ++ GT  ++ P++  R        K+YG TVD+WS+GV       G  P+
Sbjct: 374 TMVGTPYWMAPEVVTR--------KQYGPTVDIWSLGVMCIEMIEGEPPY 499
>15910
          Length = 1361

 Score = 73.2 bits (178), Expect = 3e-13,   Method: Compositional matrix adjust.
 Identities = 41/106 (38%), Positives = 60/106 (56%)
 Frame = +2

Query: 116 LRDVVGGMNHLRENGIVHRDIKPGNIMRVIGEDGQSVYKLTDFGAARELEDDEQFVSLYG 175
           + D++ G+ ++  NG+VHRD+KP N++     D  S  KL DFG +R +E + Q  ++ G
Sbjct: 482 ISDILHGVQYIHANGVVHRDLKPENLLYECMTD-DSKLKLADFGLSRIIEPEVQMSTVCG 658

Query: 176 TEEYLHPDMYERAVLRKDHQKKYGATVDLWSVGVTFYHAATGSLPF 221
           T  Y  P+     VL+ D   KY  +VD+WSVGV  Y    G  PF
Sbjct: 659 TPGYCAPE-----VLKGD---KYTPSVDMWSVGVIAYILLCGYEPF 772
>31885
          Length = 529

 Score = 73.2 bits (178), Expect = 4e-13,   Method: Compositional matrix adjust.
 Identities = 40/99 (40%), Positives = 56/99 (56%)
 Frame = -2

Query: 123 MNHLRENGIVHRDIKPGNIMRVIGEDGQSVYKLTDFGAARELEDDEQFVSLYGTEEYLHP 182
           +++LR   IVHRDIKP NI+     D Q    +TDF  A +LEDDE   S  GT  Y+ P
Sbjct: 333 LDYLRSQKIVHRDIKPDNILL----DEQGHCHVTDFNIATQLEDDELATSTSGTRPYMAP 166

Query: 183 DMYERAVLRKDHQKKYGATVDLWSVGVTFYHAATGSLPF 221
           ++Y  A+   + ++ YG  VD WS+GV+ +       PF
Sbjct: 165 EVYGVAI---NERRGYGFPVDWWSLGVSLFELLKKRRPF 58
>19301
          Length = 712

 Score = 67.8 bits (164), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 46/147 (31%), Positives = 71/147 (48%)
 Frame = +2

Query: 15  LGQGATANVFRGRHKKTGDLYAVKVFNNISFLRPVDVQMREFEVLKKLNHKNIVKLFAIE 74
           LG GA   VF G  K   +  AVK           D++  +   L+KLNH NI+    + 
Sbjct: 329 LGSGAQGAVFLG--KLCAEEVAVKKVR--------DIKETDIRNLRKLNHPNIISFKGVC 478

Query: 75  EETTTRHKVLIMEFCPCGSLYTVLEEPSNAYGLPESEFLIVLRDVVGGMNHLRENGIVHR 134
            +       +IME+CP G LY VL +      +P +  L   + +  GMN+L  + I+HR
Sbjct: 479 TQAPCY--CIIMEYCPYGQLYEVLRDGKE---IPPALVLDWSKQIASGMNYLHSHKIIHR 643

Query: 135 DIKPGNIMRVIGEDGQSVYKLTDFGAA 161
           D+K  N++    +    V K++DFG +
Sbjct: 644 DLKSPNVLVAKND----VVKISDFGTS 712
>21079
          Length = 878

 Score = 67.0 bits (162), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 46/166 (27%), Positives = 79/166 (47%), Gaps = 2/166 (1%)
 Frame = +1

Query: 80  RHKVLIMEFCPCGSLYTVLEEPSNAYGLPESEFLIVLRDVVGGMNHLRENGIVHRDIKPG 139
           R  VL+MEF   G L+  +    + + L E + +  +R +  G+ ++    I+H D+KP 
Sbjct: 43  RTMVLVMEFVGAGELFERVIR--DDFVLTERDCVHFVRQICSGVGYMHTQSILHLDLKPE 216

Query: 140 NIMRVIGEDGQSVYKLTDFGAARELEDDEQFVSLYGTEEYLHPDMYERAVLRKDHQKKYG 199
           N++ V   D  +  K+ DFG AR  +  +    L+GT E++ P++         +  +  
Sbjct: 217 NVLCV--SDNSNQIKIIDFGLARFYKPGDSLQVLFGTPEFIAPEVV--------NYDEIN 366

Query: 200 ATVDLWSVGVTFYHAATGSLPFR--PFEGPRRNKEVMYKIITGKPS 243
            T D+WS+GV  Y   +G  P R      P    +V+   +T  PS
Sbjct: 367 FTTDMWSIGVICYILLSGLSPSRVTTMLRPWPTSQVVTTTLTMIPS 504
>12721
          Length = 821

 Score = 65.5 bits (158), Expect = 7e-11,   Method: Compositional matrix adjust.
 Identities = 50/183 (27%), Positives = 86/183 (46%), Gaps = 4/183 (2%)
 Frame = +1

Query: 55  EFEVLKKLNHKNIVKLFAIEEETTTRHKVLIMEFCPCGSLYTVLEEPSNAYGLPESEFLI 114
           E  V++  +H NIV+++            ++MEF   G+L  ++        + E +   
Sbjct: 226 EVVVMRDYHHPNIVEMY--NSYLVNDELWVVMEFMEGGALTDIVTN----NRMDEVQIAT 387

Query: 115 VLRDVVGGMNHLRENGIVHRDIKPGNIMRVIGEDGQSVYKLTDFG-AARELEDDEQFVSL 173
           V R  +  +  L  NG++HRDIK  +I+  +  DG+   KL DFG  A+  +D ++  SL
Sbjct: 388 VCRACLKALAFLHANGVIHRDIKSDSIL--LSHDGK--VKLXDFGFCAQVTQDLQKRKSL 555

Query: 174 YGTEEYLHPDMYERAVLRKDHQKKYGATVDLWSVGVTFYHAATGSLPF---RPFEGPRRN 230
            GT  ++ P++  R          YG  VD+WS+G+          PF    P +  RR 
Sbjct: 556 VGTPYWMAPEVISRL--------PYGPEVDIWSLGIMVMEMIDAEPPFFNEPPLQAMRRI 711

Query: 231 KEV 233
           +++
Sbjct: 712 RDM 720
>00392
          Length = 668

 Score = 65.1 bits (157), Expect = 9e-11,   Method: Compositional matrix adjust.
 Identities = 53/173 (30%), Positives = 84/173 (48%), Gaps = 6/173 (3%)
 Frame = +3

Query: 55  EFEVLKKLNHKNIVKLFAIEEETTTRHK---VLIMEFCPCGSLYTVLEEPSNAYGLPESE 111
           E E+LK+L H NIV+ F   EE   R++   +L+ E    G+L T L+     +  P  +
Sbjct: 81  EAEMLKELQHPNIVRFFDYWEEHNHRNRKVIILVTELMTSGTLKTYLKR----FKKPNVK 248

Query: 112 FLI-VLRDVVGGMN--HLRENGIVHRDIKPGNIMRVIGEDGQSVYKLTDFGAARELEDDE 168
            L    R V+ G+   H R   ++HRD+K  NI  + G  G    K+ D G A  L++  
Sbjct: 249 ILKNWCRQVLKGLYFLHTRTPPVIHRDLKCDNIF-ITGPTGS--VKIGDLGLA-TLKNQS 416

Query: 169 QFVSLYGTEEYLHPDMYERAVLRKDHQKKYGATVDLWSVGVTFYHAATGSLPF 221
              S+ GT E++ P+MYE         + Y   VD+++ G+     A+   P+
Sbjct: 417 FAKSVIGTPEFMAPEMYE---------EHYDEAVDVYAFGMCMLEMASSEYPY 548
>09606
          Length = 1300

 Score = 64.7 bits (156), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 58/237 (24%), Positives = 105/237 (44%), Gaps = 24/237 (10%)
 Frame = -3

Query: 9    WLLSDILGQGATANVFRGRHKKTGDLYAVKVFNNISFLRP-VDVQMREFEVLKKLNHKNI 67
            ++L + LG+G  + +++GR K T +  A+         RP V   +R   +   ++H N+
Sbjct: 1109 FVLYEELGKGEHSIIYKGRRKGTINFVAIHCIEKCK--RPEVTNTVR---MTHDISHPNV 945

Query: 68   VKLFAIEEETTTRHKVLIMEFCPCGSLYTVLEEPSNAYGLPESEFLIVLRDVVGGMNHLR 127
            V+     E  T+ H  L++E C  GSL  +L   +  + LPE+        +V G++++ 
Sbjct: 944  VQFHEWYE--TSNHLWLVVELCTGGSLADIL---AQDHHLPETSIRDFGIHLVTGLHYIH 780

Query: 128  ENGIVHRDIKPGNIMRVIGEDGQSVYKLTDFGAAR-ELEDDEQF---------------- 170
              GI+  D++P  ++     D   V K  DFG ++ E E+ E+                 
Sbjct: 779  SLGILFHDLRPSKVLL----DTSGVLKFADFGLSKVEGENLEELFFKFAEAGDQWNIQSA 612

Query: 171  ------VSLYGTEEYLHPDMYERAVLRKDHQKKYGATVDLWSVGVTFYHAATGSLPF 221
                  V   G+  Y+ P++++ A        +     DLW++G  FY   +G  PF
Sbjct: 611  EEMMKQVPTSGSPTYMAPEVFQGA--------EPSIMSDLWALGCVFYEMFSGHPPF 465
>12786
          Length = 460

 Score = 58.9 bits (141), Expect = 7e-09,   Method: Compositional matrix adjust.
 Identities = 40/132 (30%), Positives = 55/132 (41%), Gaps = 15/132 (11%)
 Frame = -3

Query: 106 GLPESEFLIVLRDVVGGMNHLRENGIVHRDIKPGNIMRVIGEDGQSVYKLTDFGAARELE 165
           GL         R+++  +  L   G++H D+KP N M V G       KL DFG A  L+
Sbjct: 422 GLDRMMIKFYWREMLRAVKALHNEGVIHSDLKPANFMLVAGN-----LKLIDFGIANTLQ 258

Query: 166 DDEQFV---SLYGTEEYLHP------------DMYERAVLRKDHQKKYGATVDLWSVGVT 210
            D+  V   S  GT  Y+ P            D  E    R   + K G   D+WS+G  
Sbjct: 257 QDKTSVLKDSRVGTPSYMSPEAIMAACDDSADDSMEEDGHRTKPKYKVGVRSDVWSLGCI 78

Query: 211 FYHAATGSLPFR 222
            Y+   G  PF+
Sbjct: 77  LYNMVYGRTPFQ 42
>17253
          Length = 483

 Score = 58.2 bits (139), Expect = 1e-08,   Method: Composition-based stats.
 Identities = 45/149 (30%), Positives = 69/149 (46%), Gaps = 10/149 (6%)
 Frame = -1

Query: 28  HKKTGDLYAVKVFNNISFLRPVDVQMREFEVLKKL-NHKNIVKLFAIEEETTTRHKVLIM 86
           H +  D  AVK  N  +        +RE  +++KL  H N+V        T +   +++M
Sbjct: 480 HARQWDTVAVKTHNEAATDAEKSEFLRELSIMRKLPRHPNVVSFMGCC--TMSDPALILM 307

Query: 87  EFCPCGSLYTVLEE---------PSNAYGLPESEFLIVLRDVVGGMNHLRENGIVHRDIK 137
           EFC  G L + L +          S A  L   +F      V  GM H+  N IVHRD+ 
Sbjct: 306 EFCCHGDLLSFLRKRRPDRTVFLTSTANDLTARDFFSFALHVARGMAHVANNKIVHRDVA 127

Query: 138 PGNIMRVIGEDGQSVYKLTDFGAARELED 166
             N++  I E  ++V K++DFG +R + D
Sbjct: 126 ARNVL--ISE--RNVCKVSDFGLSRRVGD 52
>04591
          Length = 1117

 Score = 58.2 bits (139), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 46/165 (27%), Positives = 81/165 (49%), Gaps = 6/165 (3%)
 Frame = -2

Query: 53   MREFEVLKKLNHKNIVKLFAI---EEETTTRHK---VLIMEFCPCGSLYTVLEEPSNAYG 106
            +RE ++L++L H+N+V+L  I   +     R+K    LI E+C    L  +L      + 
Sbjct: 1077 LREIKILQQLEHENVVQLQEICHTQAGPYNRYKSTFYLIFEYCDY-DLAGLLNNLRVKFS 901

Query: 107  LPESEFLIVLRDVVGGMNHLRENGIVHRDIKPGNIMRVIGEDGQSVYKLTDFGAARELED 166
            L + + L  +  ++ G+ ++    I+HRDIK  NI+  +  DG  V KL DFG +R    
Sbjct: 900  LADKKNL--MSQLLNGLFYIHTKQILHRDIKAANIL--LTRDG--VLKLADFGLSRPWVK 739

Query: 167  DEQFVSLYGTEEYLHPDMYERAVLRKDHQKKYGATVDLWSVGVTF 211
             ++  +   T  Y  P++          +++YG  +D+W VG   
Sbjct: 738  SKRLTNRVVTLWYRPPELLL-------GEREYGPEIDMWGVGCIM 625
>03240
          Length = 1683

 Score = 57.0 bits (136), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 72/280 (25%), Positives = 106/280 (37%), Gaps = 53/280 (18%)
 Frame = -3

Query: 15   LGQGATANVFRGRHKKTGDLYAVKVFNNISFLRPVDVQ--MREFEVLKKLNHKNIVKLFA 72
            LG GA   V   R   TG LYA+K       L+   V     E ++L + +++ +VKL+ 
Sbjct: 1267 LGVGAFGEVSLCRKNDTGMLYAMKTLRKSDVLKRNQVAHVKAERDILAEADNEWVVKLYY 1088

Query: 73   IEEETTTRHKVLIMEFCPCGSLY------TVLEEPSNAYGLPESEFLIVLRDVVGGMNHL 126
              ++    +   +M++ P G L        +L+EP   + + E         +V  +  +
Sbjct: 1087 SFQDHN--YLYFVMDYVPGGDLMGLLIRMEILDEPLARFYVAE---------LVQAIESV 941

Query: 127  RENGIVHRDIKPGNIMRVIGEDGQSVYKLTDFGA-------------------ARE---- 163
               G +HRDIKP NI+  I  +G    KLTDFG                    AR+    
Sbjct: 940  HRMGFIHRDIKPDNIL--IDRNGH--IKLTDFGLCTGFRWTHNSKYYQRDGTHARQDSME 773

Query: 164  --LEDDEQFV--------------------SLYGTEEYLHPDMYERAVLRKDHQKKYGAT 201
               + DEQ                      SL GT  Y+ P++  R          Y + 
Sbjct: 772  VKCQLDEQCQCEILKPLERRRKREQRCLAHSLVGTPNYIAPEVLSRL-------GGYTSV 614

Query: 202  VDLWSVGVTFYHAATGSLPFRPFEGPRRNKEVMYKIITGK 241
             D WSVGV  +    G  PF          E  YK+I  K
Sbjct: 613  CDWWSVGVILFEMLVGHPPFY----ANTPAETQYKVINWK 506
>06405
          Length = 1965

 Score = 57.0 bits (136), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 48/214 (22%), Positives = 91/214 (42%), Gaps = 2/214 (0%)
 Frame = +1

Query: 15  LGQGATANVFRGRHKKTGDLYAVKVFNNISFLRPVDVQMREFEVLKKLNHKNIVKLFAIE 74
           LG G   +V+    K+   + AVK     +    ++  + E  ++K++ H N+V+L  + 
Sbjct: 283 LGGGQYGDVYEAMWKRYNKIVAVKTLKEDTMA--LNDFLEEAAIMKEMKHPNLVQLLGV- 453

Query: 75  EETTTRHKV--LIMEFCPCGSLYTVLEEPSNAYGLPESEFLIVLRDVVGGMNHLRENGIV 132
               TR     ++ EF P G+L   L   +     P +  + +   +  GM +L     +
Sbjct: 454 ---CTREPPFYIVTEFMPHGNLLDYLRSSTREENGP-TALMYMATQIASGMAYLETKNFI 621

Query: 133 HRDIKPGNIMRVIGEDGQSVYKLTDFGAARELEDDEQFVSLYGTEEYLHPDMYERAVLRK 192
           HRD+   N +        ++ K+ DFG AR ++DD  + +  G +  +     E      
Sbjct: 622 HRDLAARNCLVA----DSNMVKVADFGLARLMKDD-TYTAHIGAKFPIKWTAPEGLAF-- 780

Query: 193 DHQKKYGATVDLWSVGVTFYHAATGSLPFRPFEG 226
               ++    D+W+ GV  +  AT  +   P+ G
Sbjct: 781 ---NRFSTRSDIWAFGVLLWELATYGM--SPYPG 867
>30755
          Length = 1137

 Score = 55.1 bits (131), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 35/122 (28%), Positives = 59/122 (48%), Gaps = 1/122 (0%)
 Frame = +2

Query: 118 DVVGGMNHLRENGIVHRDIKPGNIMRVIGEDGQSVYKLTDFGAARE-LEDDEQFVSLYGT 176
           +++  + +L   GI++RD+K  N++  + +DG    K+ DFG  +E +       +  GT
Sbjct: 56  EIISALGYLHSQGIIYRDLKLENLL--LDKDGH--IKVADFGLCKEDITYGRTTKTFCGT 223

Query: 177 EEYLHPDMYERAVLRKDHQKKYGATVDLWSVGVTFYHAATGSLPFRPFEGPRRNKEVMYK 236
            EYL P++ +           YG  VD W  GV  Y    G LPF       R+ +V++ 
Sbjct: 224 PEYLAPEVLD--------DNDYGRAVDWWGTGVVMYEMICGRLPFY-----NRDHDVLFT 364

Query: 237 II 238
           +I
Sbjct: 365 LI 370
>01392
          Length = 1806

 Score = 55.1 bits (131), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 37/121 (30%), Positives = 57/121 (47%), Gaps = 6/121 (4%)
 Frame = -1

Query: 107  LPESEFLIVLRDVVGGMNHLRENGIVHRDIKPGNIMRVIGEDGQSVYKLTDFGAARELED 166
            L E E  +V+R +   ++ L   GI HRD+KP NI+    +D   V K+ DF  A  +  
Sbjct: 1800 LCEREASLVVRHIARALDFLHSKGIAHRDLKPENILCEHLDDVVPV-KICDFDLASGISC 1624

Query: 167  D------EQFVSLYGTEEYLHPDMYERAVLRKDHQKKYGATVDLWSVGVTFYHAATGSLP 220
            D       + ++  G+ EY+ P++ +  V        Y    DLWS+G+  Y    G  P
Sbjct: 1623 DGDGTKTPELLTPVGSAEYMAPEVVDAWV---GDSFSYDKRCDLWSLGIILYIMLCGYPP 1453

Query: 221  F 221
            F
Sbjct: 1452 F 1450
>09007
          Length = 1440

 Score = 53.9 bits (128), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 51/225 (22%), Positives = 95/225 (42%), Gaps = 9/225 (4%)
 Frame = -1

Query: 11  LSDILGQGATANVFRG-RHKKTGD--LYAVKVFNNISFLRPVDVQMREFEVLKKLNHKNI 67
           LS  LGQG    V +     ++G+    AVK  +     +     ++E  +++ L+H+NI
Sbjct: 867 LSKSLGQGHFGTVRQAIWTAESGEKVQVAVKCLSKDKIHKDGQEFLKETAIMQMLDHENI 688

Query: 68  VKLFAIEEETTTRHKVLIMEFCPCGSLYTVLEEPSNAYGLPESEFLIVLRDVVGGMNHLR 127
           V+++ +  +      +L+ E  P  SL   ++E S              + V  GM++L 
Sbjct: 687 VRVYGVVMDNGA-DIMLVTELAPMRSLLECVKEVSARVDFSVPRLCDFSQQVCDGMSYLE 511

Query: 128 ENGIVHRDIKPGNIMRVIGEDGQSVYKLTD------FGAARELEDDEQFVSLYGTEEYLH 181
              +VHRD+   NI+       +S  K++D       GA +E    +Q + L     +  
Sbjct: 510 SKRLVHRDLAARNILLF----SKSKVKISDVGVSGALGAGKEYYQSQQTIHLQNAVAWCA 343

Query: 182 PDMYERAVLRKDHQKKYGATVDLWSVGVTFYHAATGSLPFRPFEG 226
           P+ +            + +  D+W+ GV  +   T    F+P+ G
Sbjct: 342 PESFRNLC--------FSSASDVWAFGVLLWEFFTHG--FQPWAG 238
>01060
          Length = 1800

 Score = 53.9 bits (128), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 58/209 (27%), Positives = 90/209 (43%), Gaps = 12/209 (5%)
 Frame = +1

Query: 15  LGQGATANVFRGRHKKTGDLYAVKVFNNISFLRPVD-----VQMREFEVLKKLNHKNIVK 69
           +G+G    V++ RH+ TG   A+K       LR  +       +RE  +L++L H NIV 
Sbjct: 97  IGEGTYGVVYKCRHRATGRKLAMKKIR----LRGSEDGVPSSAIREIAMLRELRHTNIVC 264

Query: 70  L--FAIEEETTTRHKVLIMEFCPCGSLYTVLEEPSNAYGLPESEFLIVLRDVVGGMNHLR 127
           L    +E+E       L+ EF     L   +++      L        +  +V G+    
Sbjct: 265 LEDVIMEDE----RLFLVFEFLSM-DLKMYIDKFPEGVVLDRRLVKSYVFQIVTGIXFCH 429

Query: 128 ENGIVHRDIKPGNIMRVIGEDGQSVYKLTDFGAAREL-----EDDEQFVSLYGTEEYLHP 182
           +  IVHRD+KP N++  I   G    K+ DFG AR           + V+L+    Y  P
Sbjct: 430 QRRIVHRDLKPQNLL--INHTG--AIKIADFGMARTFALPVRAYTHEVVTLW----YRAP 585

Query: 183 DMYERAVLRKDHQKKYGATVDLWSVGVTF 211
           ++   A        KY   VD+WS+G  F
Sbjct: 586 EILMGA-------SKYSTPVDVWSIGTIF 651
>26711
          Length = 405

 Score = 53.5 bits (127), Expect = 3e-07,   Method: Composition-based stats.
 Identities = 33/108 (30%), Positives = 55/108 (50%)
 Frame = -2

Query: 115 VLRDVVGGMNHLRENGIVHRDIKPGNIMRVIGEDGQSVYKLTDFGAARELEDDEQFVSLY 174
           V++ V+  + H+   G+VH D+KP N++ + G+   SV +L DFG AR+L   ++    +
Sbjct: 401 VVKQVLDILQHVHAQGVVHMDLKPSNLL-LSGDKLDSV-QLIDFGLARKLYPPQETFLNH 228

Query: 175 GTEEYLHPDMYERAVLRKDHQKKYGATVDLWSVGVTFYHAATGSLPFR 222
           GT  +  P+  +         K      D+W VGV  Y   +G  PF+
Sbjct: 227 GTPGFTSPEALD--------VKPISTASDVWGVGVLAYILLSGQSPFQ 108
>19761
          Length = 473

 Score = 53.1 bits (126), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 37/110 (33%), Positives = 53/110 (48%), Gaps = 3/110 (2%)
 Frame = -3

Query: 106 GLPESEFLIVLRDVVGGMNHLRENG--IVHRDIKPGNIMRVIGEDGQSVYKLTDFGAARE 163
           GLPE   +  L      +N++  +   I+HRD+KP NI   + E G    +L D G AR+
Sbjct: 435 GLPERLIVCWLMQTASALNYMHTHTPVILHRDLKPQNI--YVTEKGD--VRLGDLGLARK 268

Query: 164 LEDDEQFV-SLYGTEEYLHPDMYERAVLRKDHQKKYGATVDLWSVGVTFY 212
           L     F  S  GT  YL P++          Q+ Y +  D+WS+G  FY
Sbjct: 267 LTGPADFATSQVGTIMYLSPEILS--------QQPYNSKSDIWSLGCVFY 142
>21808
          Length = 1011

 Score = 52.0 bits (123), Expect = 8e-07,   Method: Compositional matrix adjust.
 Identities = 48/189 (25%), Positives = 85/189 (44%), Gaps = 1/189 (0%)
 Frame = +1

Query: 53  MREFEVLKKLNHKNIVKLFAIEEETTTRHKVLIMEFCPCGSLYTVLEEPSNAYGLPESEF 112
           + E +++KKL H  +++L+A+   T      +I E    GSL   L+       LP    
Sbjct: 76  LAEAQIMKKLRHPKLIQLYAVC--TQDDPIFIITELMKNGSLLEFLQGKGRVLKLPA--L 243

Query: 113 LIVLRDVVGGMNHLRENGIVHRDIKPGNIMRVIGEDGQSVYKLTDFGAARELEDDEQFVS 172
           + +   +  GM +L     +HRD+   NI+     D  +V K+ DFG AR +++DE + +
Sbjct: 244 IDIGAQIACGMAYLESQNYIHRDLAARNILV---SDNNTV-KIADFGLARVIKEDE-YEA 408

Query: 173 LYGTEEYLHPDMYERAVLRKDHQKKYGATVDLWSVGVTFYHAAT-GSLPFRPFEGPRRNK 231
             G    +     E A     +  ++    D+WS G+      T G +P+        N 
Sbjct: 409 RVGARFPIKWTAPEAA-----NYNRFTIKSDVWSFGILLTETVTYGRVPYPGMT----NA 561

Query: 232 EVMYKIITG 240
           EV++++  G
Sbjct: 562 EVLHQVEHG 588
>13212
          Length = 1067

 Score = 51.6 bits (122), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 36/130 (27%), Positives = 64/130 (49%), Gaps = 1/130 (0%)
 Frame = -1

Query: 92   GSLYTVLEEPSNAYGLPESEFLIVLRDVVGGMNHLRENGIVHRDIKPGNIMRVIGEDGQS 151
             S+   LE+P     + E++   V  ++   ++ L  + ++HRDIK GN++  I  DG+ 
Sbjct: 1019 DSIMVDLEKP-----MTEAQICYVCHEMCMALDFLHRHHVIHRDIKAGNVLLTI--DGE- 864

Query: 152  VYKLTDFG-AARELEDDEQFVSLYGTEEYLHPDMYERAVLRKDHQKKYGATVDLWSVGVT 210
              KL DFG +A+  +  ++  +  GT  ++ P++     L+      Y    D+WS+GVT
Sbjct: 863  -VKLADFGVSAKNTQTQQKRDTFIGTPYWMAPEVVLCETLK---DTPYDFKADIWSLGVT 696

Query: 211  FYHAATGSLP 220
                A    P
Sbjct: 695  LIEFAQIEPP 666
>19094
          Length = 898

 Score = 50.8 bits (120), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 35/114 (30%), Positives = 58/114 (50%), Gaps = 1/114 (0%)
 Frame = +1

Query: 107 LPESEFLIVLRDVVGGMNHLRENGIVHRDIKPGNIMRVIGEDGQSVYKLTDFGAARELED 166
           L E E   +L   + G+ +L     +HRDIK GNI+  +  +G +  KL DFG A +L D
Sbjct: 49  LVEREIATILYYTLKGL*YLHSRRKIHRDIKAGNIL--LNNEGHA--KLADFGVAGQLTD 216

Query: 167 D-EQFVSLYGTEEYLHPDMYERAVLRKDHQKKYGATVDLWSVGVTFYHAATGSL 219
              +  ++ GT  ++ P++ +        +  Y    D+WS+G+T    A G+L
Sbjct: 217 TMAKRNTVIGTPYWMAPEVIQ--------EIGYDCVADIWSLGITALEMAEGNL 354
>29581
          Length = 1278

 Score = 50.1 bits (118), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 47/192 (24%), Positives = 85/192 (44%), Gaps = 4/192 (2%)
 Frame = -2

Query: 59   LKKLNHKNIVKLFAIEEETTTRHKVLIMEFCPCGSLYTVLEEPSNAYGLPESEFLIVLRD 118
            L  L H+NIV+L  +    +     L+ME+C    L ++L+     +   ES+   ++  
Sbjct: 1193 LLNLRHQNIVQLQEVVVGKSLDSLFLVMEYCE-QDLASLLDNMPAPFS--ESQVKCIVLQ 1023

Query: 119  VVGGMNHLRENGIVHRDIKPGNIMRVIGEDGQSVYKLTDFGAARELEDDEQFVSLYG-TE 177
            ++ G+ +L E  I+HRD+K  N++       +   K+ DFG AR           YG  +
Sbjct: 1022 LLKGLRYLHEAFIIHRDLKVSNLLMT----DKGCVKIADFGLARN----------YGKPQ 885

Query: 178  EYLHPD---MYERAVLRKDHQKKYGATVDLWSVGVTFYHAATGSLPFRPFEGPRRNKEVM 234
            + + P    ++ RA       K +   +D+WS G        G  P  P     +  E++
Sbjct: 884  KPMTPKVVTLWYRAPELLFGSKTHSTAIDMWSAGCIL-GELLGHKPLMPGRSDLQQIELI 708

Query: 235  YKIITGKPSGAI 246
             +++ G P+  I
Sbjct: 707  MELL-GTPNDTI 675
>18484
          Length = 635

 Score = 50.1 bits (118), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 31/105 (29%), Positives = 53/105 (50%), Gaps = 1/105 (0%)
 Frame = +1

Query: 118 DVVGGMNHLRENGIVHRDIKPGNIMRVIGEDGQSVYKLTDFGAARE-LEDDEQFVSLYGT 176
           ++  G+  L + GI++RD+K  N+M     D +   K+ DFG  +E +  D    +  GT
Sbjct: 67  EIAVGLFFLHDQGIIYRDLKLDNVML----DSEGHIKIADFGMCKEGMTGDATTRTFCGT 234

Query: 177 EEYLHPDMYERAVLRKDHQKKYGATVDLWSVGVTFYHAATGSLPF 221
            +Y+ P++    VL + + K    +VD W+ GV  +    G  PF
Sbjct: 235 PDYIAPEI----VLYQPYSK----SVDWWAYGVLLFEMLAGQPPF 345
>17975
          Length = 449

 Score = 49.3 bits (116), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 40/135 (29%), Positives = 65/135 (48%), Gaps = 1/135 (0%)
 Frame = +3

Query: 26  GRHKKTGDLYAVKVFNNISFLRPVDVQM-REFEVLKKLNHKNIVKLFAIEEETTTRHKVL 84
            RH  TG+  AVKV +           + +E   +K + H N+V+L+ + +  T  +  L
Sbjct: 24  ARHVFTGEKVAVKVIDKTKLDEVSRSHLFQEVRCMKLVQHPNVVRLYEVIDTQTKLY--L 197

Query: 85  IMEFCPCGSLYTVLEEPSNAYGLPESEFLIVLRDVVGGMNHLRENGIVHRDIKPGNIMRV 144
           I+E    G +Y  +   S   GL E       R +V  +++  +  +VHRD+KP N   V
Sbjct: 198 ILELGDGGDMYDYIMRHSG--GLEEKLAKRYFRQIVEAISYCHKLHVVHRDLKPEN---V 362

Query: 145 IGEDGQSVYKLTDFG 159
           +  +   + KLTDFG
Sbjct: 363 VFFEKPGLVKLTDFG 407
>26560
          Length = 398

 Score = 48.5 bits (114), Expect = 9e-06,   Method: Compositional matrix adjust.
 Identities = 34/114 (29%), Positives = 55/114 (48%)
 Frame = -1

Query: 109 ESEFLIVLRDVVGGMNHLRENGIVHRDIKPGNIMRVIGEDGQSVYKLTDFGAARELEDDE 168
           E E      +V+ G+ H+    +V+RD+KP NI+  + E+G    +++D G A +     
Sbjct: 359 EKEVRFYAAEVMLGLEHMHSRFVVYRDLKPANIL--LDENGH--VRISDLGLACDFSKKR 192

Query: 169 QFVSLYGTEEYLHPDMYERAVLRKDHQKKYGATVDLWSVGVTFYHAATGSLPFR 222
              S+ GT  Y+ P+     VL K   + Y ++ D +S G   Y    G  PFR
Sbjct: 191 PHASV-GTHGYMAPE-----VLMKG--QSYDSSADWFSFGCMLYKLLKGHSPFR 54
>01966
          Length = 1735

 Score = 42.0 bits (97), Expect(2) = 2e-05,   Method: Compositional matrix adjust.
 Identities = 47/151 (31%), Positives = 68/151 (45%), Gaps = 10/151 (6%)
 Frame = -1

Query: 22   NVFRG---RHKKTGDLYAVKVFNNISFLRPVD-----VQMREFEVLKKLNHKNIVKL--F 71
            NV RG   RH+ TG   A+K       LR  +       +RE  +L++L H NIV L   
Sbjct: 1675 NVRRGL*CRHRATGRKLAMKKIR----LRGSEDGVPSSAIREIAMLRELRHTNIVCLEDV 1508

Query: 72   AIEEETTTRHKVLIMEFCPCGSLYTVLEEPSNAYGLPESEFLIVLRDVVGGMNHLRENGI 131
             +E+E       L+ EF     L   +++      L        +  +V G+N   +  I
Sbjct: 1507 IMEDERL----FLVFEFLSM-DLKMYIDKFPEGVVLDRRLVKSYVFQIVTGINFCHQRRI 1343

Query: 132  VHRDIKPGNIMRVIGEDGQSVYKLTDFGAAR 162
            VHRD+KP N++  I   G    K+ DFG AR
Sbjct: 1342 VHRDLKPQNLL--INHTG--AIKIADFGMAR 1262

 Score = 24.6 bits (52), Expect(2) = 2e-05,   Method: Compositional matrix adjust.
 Identities = 8/15 (53%), Positives = 10/15 (66%)
 Frame = -3

Query: 197  KYGATVDLWSVGVTF 211
            KY   VD+WS+G  F
Sbjct: 1178 KYSTPVDVWSIGTIF 1134
>28157
          Length = 400

 Score = 47.0 bits (110), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 33/115 (28%), Positives = 60/115 (52%), Gaps = 3/115 (2%)
 Frame = +3

Query: 53  MREFEVLKKLNHKNIVKLFAIEEETTTRHKVLIMEFCPCGSLYTVL--EEPSNAYGLPES 110
           M+E + L +++H NIV L+    +       L+ME+   GSLY VL    P   Y    +
Sbjct: 54  MQELKQLSRVSHPNIVCLYGACRDHPV---CLVMEYAEGGSLYNVLHGSGPQPQYTAAHA 224

Query: 111 -EFLIVLRDVVGGMNHLRENGIVHRDIKPGNIMRVIGEDGQSVYKLTDFGAAREL 164
             +L+     V  ++ ++   ++HRD+KP N++ +  + G  + K+ DFG A ++
Sbjct: 225 MNWLLQCALGVEYLHGMKPKALIHRDLKPPNLLLI--QCGTKL-KICDFGTACDI 380
>11780
          Length = 1713

 Score = 45.4 bits (106), Expect = 7e-05,   Method: Compositional matrix adjust.
 Identities = 37/152 (24%), Positives = 73/152 (48%)
 Frame = +3

Query: 11  LSDILGQGATANVFRGRHKKTGDLYAVKVFNNISFLRPVDVQMREFEVLKKLNHKNIVKL 70
           + + +G+G   +V++G ++  G   A+K   +    R     ++E  V+  L H N+V+L
Sbjct: 609 IGEAIGKGDFGDVYKGMYR--GQPVAIKQLKDKD--RGEQSFLQEASVMTSLRHDNLVRL 776

Query: 71  FAIEEETTTRHKVLIMEFCPCGSLYTVLEEPSNAYGLPESEFLIVLRDVVGGMNHLRENG 130
             +    T     L+ EF   G+L   L     +  + + + +    D    M +L    
Sbjct: 777 IGVVLGETI---FLVTEFMGKGNLVEYLRSRGRSV-ITKKDQINFATDTCAAMEYLESKR 944

Query: 131 IVHRDIKPGNIMRVIGEDGQSVYKLTDFGAAR 162
           +VHRD+   N++  + +DG++  K++DFG A+
Sbjct: 945 LVHRDLAARNVL--VHDDGKA--KVSDFGLAK 1028
>13066
          Length = 551

 Score = 43.9 bits (102), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 43/164 (26%), Positives = 69/164 (42%), Gaps = 9/164 (5%)
 Frame = +3

Query: 54  REFEVLKKLNHKNIVKLFAIEEETTTRHKVLIMEFCPCGSLYTVLEEPSNAYGLPESEFL 113
           RE ++L KL+H  I+++ +I +        + M F   G L T ++E      + E +  
Sbjct: 123 RELDLLTKLDHPYIIQIHSILQRXPKN--FIFMRFAERGDLLTYIQEVGF---VKEKQAK 287

Query: 114 IVLRDVVGGMNHLRENGIVHRDIKPGNIMRVIGEDGQSVYKLTDFGAAREL--EDDEQFV 171
           I    +   +N+L    + HRD+K  NI+           KL DFG A     E  E+++
Sbjct: 288 IWFYQMTTALNYLHSYDVAHRDLKCENILL----SSHFNVKLADFGFACACITESGEKYM 455

Query: 172 S--LYGTEEYLHPDMYERAVLRKDHQKKYGA-----TVDLWSVG 208
           S    G+  Y  P++             YGA       D WS+G
Sbjct: 456 SRTYCGSAAYAAPEIV------------YGAPYAPKVADAWSLG 551
>21433
          Length = 590

 Score = 42.7 bits (99), Expect = 5e-04,   Method: Composition-based stats.
 Identities = 31/97 (31%), Positives = 48/97 (49%)
 Frame = +2

Query: 125 HLRENGIVHRDIKPGNIMRVIGEDGQSVYKLTDFGAARELEDDEQFVSLYGTEEYLHPDM 184
           H R+  ++HRDIKP N++  +    +   K+ DFG +       +  ++ GT +YL P+M
Sbjct: 218 HYRK--VIHRDIKPENLLLGL----KGDLKIADFGWSVHAPSSRR-TTMCGTLDYLPPEM 376

Query: 185 YERAVLRKDHQKKYGATVDLWSVGVTFYHAATGSLPF 221
            E         K +   VDLWS+GV  Y    G+ P 
Sbjct: 377 VE--------GKTHDENVDLWSLGVLCYEFLVGTPPL 463
>32359
          Length = 928

 Score = 35.8 bits (81), Expect(2) = 8e-04,   Method: Compositional matrix adjust.
 Identities = 23/83 (27%), Positives = 44/83 (53%), Gaps = 4/83 (4%)
 Frame = -1

Query: 12  SDILGQGATANVFRGRHKKTGDLYAVKVFNNISFLRPVDVQMREFEVLKKLNHKNIVKL- 70
           + ++G G+   V++ +   T +L A+K       L+    + RE ++++KL H+NIVKL 
Sbjct: 415 AKVIGNGSFGVVYQAKLVDTSELVAIK-----KVLQDKRFKNRELQIMRKLEHQNIVKLK 251

Query: 71  FAIEEETTTRHKV---LIMEFCP 90
           F        + +V   L++E+ P
Sbjct: 250 FFFYSSGEKKDEVFLNLVLEYVP 182

 Score = 25.4 bits (54), Expect(2) = 8e-04,   Method: Composition-based stats.
 Identities = 8/13 (61%), Positives = 11/13 (84%)
 Frame = -3

Query: 130 GIVHRDIKPGNIM 142
           G+ HRDIKP N++
Sbjct: 65  GVCHRDIKPQNLL 27
>03508
          Length = 1463

 Score = 42.0 bits (97), Expect = 8e-04,   Method: Compositional matrix adjust.
 Identities = 38/168 (22%), Positives = 68/168 (40%), Gaps = 10/168 (5%)
 Frame = +1

Query: 66  NIVKLFAIEEETTTRHKVLIMEFCPCGSLYTVLEEPSNAYGLPESEFLIVLRDVVGGMNH 125
           N++ L AI ++  +R   LI E         + +         + +    L +++  ++ 
Sbjct: 757 NVITLLAIVKDPVSRTPALIFEHVNNTDFKQLYQT------FTDYDIRFYLYELMKALDF 918

Query: 126 LRENGIVHRDIKPGNIMRVIGEDGQSVYKLTDFGAARELEDDEQFVSLYGTEEYLHPDM- 184
               GI+HRD+KP N+M  I  + + + +L D+G A                E+ HP M 
Sbjct: 919 CHSMGIMHRDVKPHNVM--IDHENKKL-RLIDWGLA----------------EFYHPGME 1041

Query: 185 ---------YERAVLRKDHQKKYGATVDLWSVGVTFYHAATGSLPFRP 223
                    ++   L  D+Q  Y  ++D+WS+G  F        P  P
Sbjct: 1042YNVRVASRYFKGPELLLDYQ-MYDYSLDMWSLGCMFASMIFRKEPLLP 1182
>27274
          Length = 396

 Score = 42.0 bits (97), Expect = 0.001,   Method: Composition-based stats.
 Identities = 21/64 (32%), Positives = 35/64 (54%), Gaps = 4/64 (6%)
 Frame = -1

Query: 196 KKYGATVDLWSVGVTFYHAATGSLPFRPFEGPR---RNKEVMY-KIITGKPSGAISGVQK 251
           +++G TVD+WS+G+  +   +G +PF P  G R   RN   +Y +II G       G+  
Sbjct: 360 QQHGPTVDMWSLGILLHELLSGHVPFEPERGSRQMARNMMAVYAQIIRGSSRDVCDGLAL 181

Query: 252 AENG 255
           + +G
Sbjct: 180 STHG 169
>27405
          Length = 532

 Score = 40.8 bits (94), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 41/175 (23%), Positives = 76/175 (43%), Gaps = 11/175 (6%)
 Frame = -3

Query: 21  ANVFRGRHKKTGDLYAVKVFNNISFLRPVDVQMREFEVLKKLNHKNIVKLFAIEEET--- 77
             V+  R   TG +YA+K  +         ++M+  E L  LN + ++ L +  E +   
Sbjct: 524 GEVYGCRKADTGKMYAMKCLDKKR------IKMKGGETLA-LNERIMLSLVSTGEGSPFI 366

Query: 78  --------TTRHKVLIMEFCPCGSLYTVLEEPSNAYGLPESEFLIVLRDVVGGMNHLREN 129
                   T      I++    G L+  L +        E E      +V+ G+ H+   
Sbjct: 365 VCMTYAFQTPEKLCFILDLMNGGDLHYHLSQHGV---FTEKEVRFYAAEVMLGLEHMHSR 195

Query: 130 GIVHRDIKPGNIMRVIGEDGQSVYKLTDFGAARELEDDEQFVSLYGTEEYLHPDM 184
            +V+RD+KP NI+  + E+G    +++D G A +    +   S+ GT  Y+ P++
Sbjct: 194 FVVYRDLKPANIL--LDENGH--VRISDLGLACDFSKKKPHASV-GTHGYMAPEV 45
>37602
          Length = 804

 Score = 40.8 bits (94), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 30/94 (31%), Positives = 45/94 (47%), Gaps = 1/94 (1%)
 Frame = -1

Query: 66  NIVKLFAIEEETTTRHKVLI-MEFCPCGSLYTVLEEPSNAYGLPESEFLIVLRDVVGGMN 124
           NI       +    R K+ I ME+C  GS+  +         L E +   V R+ + G++
Sbjct: 345 NIQTFVGYFDSYLRREKLWIAMEYCGGGSMQDIYHVTGP---LTEPQIAFVCRETLKGLH 175

Query: 125 HLRENGIVHRDIKPGNIMRVIGEDGQSVYKLTDF 158
           +L   G +HRDIK  NI+  + E+G    KL DF
Sbjct: 174 YLHRRGKMHRDIKGANIL--LTEEGDV--KLADF 85
>07833
          Length = 1504

 Score = 39.7 bits (91), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 43/171 (25%), Positives = 74/171 (43%), Gaps = 2/171 (1%)
 Frame = -3

Query: 53   MREFEVLKKLNHKNIVKLFAIEEETTTRHKVLIMEFCPCGSLYTVLEEPSNAYGLPESEF 112
            M EF  L+  NH N++ + A   +    + VLI +F P GSLY  L   S    + +++ 
Sbjct: 1475 MEEFPRLRIFNHPNVLPVLACCNQPP--NLVLISQFMPFGSLYNTLHGESGIV-VDQNQS 1305

Query: 113  LIVLRDVVGGMN--HLRENGIVHRDIKPGNIMRVIGEDGQSVYKLTDFGAARELEDDEQF 170
            L    D+  GM   H  E  I +  +   ++M  I ED  +   + D+  +   E  + +
Sbjct: 1304 LRFAMDIARGMEFLHSMEPTIPNFLLTSKHVM--IDEDLTARINMADYCFSFH-EKGKVY 1134

Query: 171  VSLYGTEEYLHPDMYERAVLRKDHQKKYGATVDLWSVGVTFYHAATGSLPF 221
                 +  ++ P+  +R   R D      A  D+WS  +  +   T  +PF
Sbjct: 1133 -----SPAWMAPEALQR---RPDDINTRAA--DMWSFAILMWELETREVPF 1011
>27546
          Length = 426

 Score = 38.9 bits (89), Expect = 0.008,   Method: Composition-based stats.
 Identities = 29/114 (25%), Positives = 56/114 (49%), Gaps = 1/114 (0%)
 Frame = -1

Query: 54  REFEVLKKLNHKNIVKLFAIEEETTTRHKVLI-MEFCPCGSLYTVLEEPSNAYGLPESEF 112
           RE E+L +L+H NI+++ +I +      K+ I M +   G + + +++      + E++ 
Sbjct: 333 RELEILTRLDHPNIIQIHSILQRGP---KIFIFMRYAEKGDMLSHIKKTGP---IDEAQT 172

Query: 113 LIVLRDVVGGMNHLRENGIVHRDIKPGNIMRVIGEDGQSVYKLTDFGAARELED 166
            +    +   + +L  + I HRD+K  NI+       +   K+ DFG AR   D
Sbjct: 171 KVWFFQMAKALQYLHSHDIAHRDLKCENILL----SKRLNVKIADFGFARYCRD 22
>12672
          Length = 773

 Score = 38.1 bits (87), Expect = 0.011,   Method: Compositional matrix adjust.
 Identities = 32/108 (29%), Positives = 45/108 (41%), Gaps = 5/108 (4%)
 Frame = +3

Query: 115 VLRDVVGGMNHLRENGIVHRDIKPGNIMRVIGEDGQSVYKLTDFGAARELEDDE----QF 170
           +++    G+ +L +NG VHRDIK  NI+     D +   K+ DF         E    Q 
Sbjct: 6   IVKGTASGIQYLNDNGHVHRDIKTANILL----DSEYTAKVGDFATVVSAPSGEGKTVQN 173

Query: 171 VSLY-GTEEYLHPDMYERAVLRKDHQKKYGATVDLWSVGVTFYHAATG 217
            S+  GT  YL P+     V  K         +D +S GV      TG
Sbjct: 174 ASVVIGTAAYLAPEAIHFDVSTK---------LDSYSFGVVLLEVITG 290
>28638
          Length = 1458

 Score = 38.1 bits (87), Expect = 0.012,   Method: Compositional matrix adjust.
 Identities = 24/94 (25%), Positives = 41/94 (43%)
 Frame = -1

Query: 128 ENGIVHRDIKPGNIMRVIGEDGQSVYKLTDFGAARELEDDEQFVSLYGTEEYLHPDMYER 187
           E  I+H D+KP NI+  +    +S  K+ DFG++ +L   ++      +  Y  P++   
Sbjct: 777 EMNIIHCDLKPENIL--LCNPKRSAIKIVDFGSSCQL--GQRIYQYIQSRFYRSPEVLLG 610

Query: 188 AVLRKDHQKKYGATVDLWSVGVTFYHAATGSLPF 221
                     Y   +D+WS+G       TG  P 
Sbjct: 609 V--------PYDLAIDMWSLGCILVEMHTGEPPL 532
>11185
          Length = 473

 Score = 37.4 bits (85), Expect = 0.022,   Method: Compositional matrix adjust.
 Identities = 28/123 (22%), Positives = 52/123 (42%), Gaps = 23/123 (18%)
 Frame = +1

Query: 119 VVGGMNHLRENGIVHRDIKPGNIMRVIGEDGQSVYKLTDFGAAR-ELEDDEQF------- 170
           +V G++++   GI+  D++P  ++     D   V K  DFG ++ E E+ E+        
Sbjct: 28  LVTGLHYIHSLGILFHDLRPSKVLL----DTSGVLKFADFGLSKVEGENLEELFFKFAEA 195

Query: 171 ---------------VSLYGTEEYLHPDMYERAVLRKDHQKKYGATVDLWSVGVTFYHAA 215
                          V   G+  Y+ P++++ A        +     DLW++G  FY   
Sbjct: 196 GDQWNIQSAEEMMKQVPTSGSPTYMAPEVFQGA--------EPSIMSDLWALGCVFYEMF 351

Query: 216 TGS 218
           +GS
Sbjct: 352 SGS 360
>00486
          Length = 797

 Score = 37.0 bits (84), Expect = 0.031,   Method: Compositional matrix adjust.
 Identities = 23/70 (32%), Positives = 32/70 (45%)
 Frame = -2

Query: 172 SLYGTEEYLHPDMYERAVLRKDHQKKYGATVDLWSVGVTFYHAATGSLPFRPFEGPRRNK 231
           +  GT EY+ P++  R          +G  VD WS+G   Y   TGS PF         K
Sbjct: 781 TFCGTIEYMAPEILTRT--------GHGKAVDWWSLGALMYDMLTGSPPFT----AENRK 638

Query: 232 EVMYKIITGK 241
           + + KI+ GK
Sbjct: 637 KTIDKILKGK 608
>29360
          Length = 363

 Score = 36.6 bits (83), Expect = 0.033,   Method: Compositional matrix adjust.
 Identities = 32/122 (26%), Positives = 60/122 (49%), Gaps = 6/122 (4%)
 Frame = +3

Query: 29  KKTGDLYAVKVF-NNISFLRPVDVQMREFEVLKKLNHK-----NIVKLFAIEEETTTRHK 82
           K T ++ A+K+  N+ S+ R   +   E  +L++L+ +     N V+ F   +     H 
Sbjct: 18  KGTSEIVAIKILKNHPSYARQGQI---EVSILQRLSQESADDYNFVRAFECFQHKN--HT 182

Query: 83  VLIMEFCPCGSLYTVLEEPSNAYGLPESEFLIVLRDVVGGMNHLRENGIVHRDIKPGNIM 142
            L+ E     +LY  L++ +    LP      + + V+  +  L++ G++H D+KP NIM
Sbjct: 183 CLVFEMLE-QNLYDFLKQ-NKFQPLPLKYIRPITQQVLTALRKLKQLGLIHADLKPENIM 356

Query: 143 RV 144
            V
Sbjct: 357 LV 362
>21800
          Length = 855

 Score = 36.6 bits (83), Expect = 0.042,   Method: Compositional matrix adjust.
 Identities = 17/48 (35%), Positives = 29/48 (60%), Gaps = 1/48 (2%)
 Frame = +2

Query: 102 SNAYGLPESEFLIVLRDVVGGMNHLREN-GIVHRDIKPGNIMRVIGED 148
           SN  G+P     +++R V+ G+N+L     I+H DIKP NI+  + ++
Sbjct: 608 SNYQGIPVHNVKLIIRQVLEGLNYLHAKCNIIHTDIKPENILICVDDN 751
>07940
          Length = 1336

 Score = 36.2 bits (82), Expect = 0.051,   Method: Compositional matrix adjust.
 Identities = 32/106 (30%), Positives = 48/106 (45%), Gaps = 3/106 (2%)
 Frame = -3

Query: 119 VVGGMNHLRENGIVHRDIKPGNIMRVIGEDGQSVYKLTDFGAARELEDDEQFVSLYGTEE 178
           V  GM +L     +HRD+   N++  + E  + V K+ DFG  R L+   QF     T +
Sbjct: 320 VARGMEYLASKQCIHRDLAARNVL--VAE--EYVLKIADFGLTRNLQ---QFDYYRKTTD 162

Query: 179 YLHPD--MYERAVLRKDHQKKYGATVDLWSVGVTFYHAAT-GSLPF 221
              P   M   A+      +KY +  D+WS GV  +   T G  P+
Sbjct: 161 GRLPVKWMAPEALF----DRKYTSKSDVWSYGVLLWEIFTLGGNPY 36
>07836
          Length = 1478

 Score = 35.4 bits (80), Expect = 0.080,   Method: Compositional matrix adjust.
 Identities = 51/201 (25%), Positives = 85/201 (42%), Gaps = 17/201 (8%)
 Frame = -1

Query: 32   GDLYAVKVFNNISFLRPVDVQMREFEVLKK--LNHKNIVKLFA--IEEETTTRHKVLIME 87
            G+  AVK+F    F        RE E+ +   L H+NI+   A  I+   +     LI +
Sbjct: 1478 GENVAVKIF----FTTEEASWFRETELYQTVLLRHENILGFIAADIKGTGSWTQLFLITD 1311

Query: 88   FCPCGSLYTVLEEPSNAYGLPESEFLIVLRDVVGGMNHLR--------ENGIVHRDIKPG 139
            +   GSL+  L     +  L  SE L +    + G+ HL         +  I HRDIK  
Sbjct: 1310 YHENGSLHDYLL----SRVLDSSEMLALAHSAICGLAHLHIEIFGTRGKPAIAHRDIKSK 1143

Query: 140  NIMRVIGEDGQSVYKLTDFGAARELEDDEQFVSLY-----GTEEYLHPDMYERAVLRKDH 194
            NI+  + ++G     + D G A     +   V +      GT+ Y+ P++ E  +  K+ 
Sbjct: 1142 NIL--VKKNGTCC--IADLGLAVRYISESNEVDVAPNPRQGTKRYMAPEVLEMLLNVKNF 975

Query: 195  QKKYGATVDLWSVGVTFYHAA 215
                 A  D+++ G+  +  A
Sbjct: 974  DAFKQA--DMYAFGLVMWEIA 918
>36481
          Length = 806

 Score = 34.7 bits (78), Expect = 0.15,   Method: Compositional matrix adjust.
 Identities = 36/133 (27%), Positives = 62/133 (46%), Gaps = 4/133 (3%)
 Frame = +2

Query: 16  GQGATANVFRGRHKKTGDLYAVKVFNNISFLRPVDVQMREFEVLKKLNHKNI-VKLFAIE 74
           G+G    V + +    GD  A+K+  N+   R  +    E  VL+KL  K+   K   ++
Sbjct: 389 GEGTFGKVVQCKDLLKGDDIALKIIKNVDKYR--EAAKLEINVLEKLREKDPHAKHMCVQ 562

Query: 75  E-ETTTRHKVLIMEFCPCG-SLYTVLEEPSNAYG-LPESEFLIVLRDVVGGMNHLRENGI 131
             +    H  + + F   G S++  L++  N+YG  P  +   +   +   +N L EN +
Sbjct: 563 MLDWFDYHGHVCISFHMLGLSVFDFLKD--NSYGAYPIEQVRHISYQLCYAVNFLHENQL 736

Query: 132 VHRDIKPGNIMRV 144
            H D+KP NI+ V
Sbjct: 737 THTDLKPENILFV 775
>01106
          Length = 878

 Score = 34.3 bits (77), Expect = 0.20,   Method: Compositional matrix adjust.
 Identities = 16/47 (34%), Positives = 28/47 (59%), Gaps = 1/47 (2%)
 Frame = +3

Query: 102 SNAYGLPESEFLIVLRDVVGGMNHLRENG-IVHRDIKPGNIMRVIGE 147
           SN  G+P     +++R V+ G++++     I+H DIKP NI+  + E
Sbjct: 621 SNYQGIPIHNVKLIIRQVLEGLSYMHAKCRIIHTDIKPENILICVDE 761
>32957
          Length = 645

 Score = 33.5 bits (75), Expect = 0.34,   Method: Composition-based stats.
 Identities = 14/38 (36%), Positives = 22/38 (57%)
 Frame = +3

Query: 175 GTEEYLHPDMYERAVLRKDHQKKYGATVDLWSVGVTFY 212
           GT EY+ P+++ER        K+YG  VD W +G+  +
Sbjct: 51  GTREYMAPEVHER--------KEYGKEVDWWGLGILLH 140
>18481
          Length = 437

 Score = 32.7 bits (73), Expect = 0.53,   Method: Compositional matrix adjust.
 Identities = 14/56 (25%), Positives = 30/56 (53%)
 Frame = -1

Query: 113 LIVLRDVVGGMNHLRENGIVHRDIKPGNIMRVIGEDGQSVYKLTDFGAARELEDDE 168
           L+V   ++  +  + +   +HRD+KP N +  +G     +Y + DFG ++  +D +
Sbjct: 188 LMVSDQLLSRLEFIHQKCFIHRDLKPDNFLMGLGRHCHRLY-IIDFGLSKRYKDTQ 24
>16708
          Length = 1397

 Score = 32.3 bits (72), Expect = 0.66,   Method: Compositional matrix adjust.
 Identities = 16/43 (37%), Positives = 24/43 (55%)
 Frame = -1

Query: 120  VGGMNHLRENGIVHRDIKPGNIMRVIGEDGQSVYKLTDFGAAR 162
            V  + H+ E G+VH D+K  N++     D     KLTD+G A+
Sbjct: 1064 VCALEHIHELGVVHMDVKADNVLV----DAHGNCKLTDYGIAQ 948
>00715
          Length = 1788

 Score = 32.0 bits (71), Expect = 0.88,   Method: Compositional matrix adjust.
 Identities = 47/200 (23%), Positives = 85/200 (42%), Gaps = 22/200 (11%)
 Frame = +1

Query: 62  LNHKNIVKLFAIEEETTTRHKV-----LIMEFCPCGSLYTVLEEPSNAYGLPESEFLIVL 116
           L H N+V +       T+ H+      L ME+    +L T+L +  +   +  S  L + 
Sbjct: 97  LRHVNVVSILG----ATSLHRFEDGAWLAMEYVGPLNLQTILND--HQQDIDSSMRLSLA 258

Query: 117 RDVVGGMNHLRENGIVHRDIKPGNIMRVIGEDGQSVYKLTDFGAARE-----LEDDEQFV 171
             +  G+++L    IVH D+KP N +  +  D +   ++ DFG   +     L+  E+  
Sbjct: 259 LQMARGLHYLHSINIVHLDLKPANCL--LTRDLK--LRIADFGCCHQLTPTGLDMGEREG 426

Query: 172 SLYGTEEYLHPDM------------YERAVLRKDHQKKYGATVDLWSVGVTFYHAATGSL 219
            + G E  L P              Y    L K  Q    +  D++S+G+T +   T   
Sbjct: 427 GMAGNELELTPVQGAWKNELAGTLAYRAPELLKGLQPSVRS--DVYSLGITLWQMCTRQ- 597

Query: 220 PFRPFEGPRRNKEVMYKIIT 239
              P+EG   +  V+Y++++
Sbjct: 598 --GPYEGVPAHA-VVYQVVS 648
>21210
          Length = 518

 Score = 31.2 bits (69), Expect = 1.4,   Method: Compositional matrix adjust.
 Identities = 17/48 (35%), Positives = 22/48 (45%)
 Frame = +3

Query: 175 GTEEYLHPDMYERAVLRKDHQKKYGATVDLWSVGVTFYHAATGSLPFR 222
           G   Y+ P   ER   R      Y    D+WS+G+T    ATG  P+R
Sbjct: 6   GCRPYMAP---ERIDPRASSHG-YDVRSDVWSLGITLMELATGRFPYR 137
>18996
          Length = 491

 Score = 31.2 bits (69), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 23/93 (24%), Positives = 42/93 (45%), Gaps = 4/93 (4%)
 Frame = +2

Query: 132 VHRDIKPGNIMRVIGEDGQSVYKLTDFGAARELEDDEQFVSLYGTE---EYLHPDMYERA 188
           +HRD+   NI+       +S  K++DFG A+    D  +  +   +   ++  P+  E  
Sbjct: 2   IHRDLAARNILV-----DRSCVKISDFGLAQFANADGYYYGISQRDIPIKWYSPEAIETC 166

Query: 189 VLRKDHQKKYGATVDLWSVGVTFYHA-ATGSLP 220
                   K+ +  D+WS GVT +   + G +P
Sbjct: 167 --------KFSSYSDVWSYGVTLFEMFSRGEIP 241
>26156
          Length = 479

 Score = 31.2 bits (69), Expect = 1.7,   Method: Compositional matrix adjust.
 Identities = 13/31 (41%), Positives = 22/31 (70%)
 Frame = -1

Query: 9   WLLSDILGQGATANVFRGRHKKTGDLYAVKV 39
           +LL  ++G+G+ A V +  HK+T  +YA+KV
Sbjct: 383 FLLLRVIGRGSYAKVLQVEHKRTKRIYAMKV 291
>15741
          Length = 402

 Score = 30.8 bits (68), Expect = 1.9,   Method: Composition-based stats.
 Identities = 15/41 (36%), Positives = 20/41 (48%)
 Frame = -3

Query: 102 SNAYGLPESEFLIVLRDVVGGMNHLRENGIVHRDIKPGNIM 142
           S A  L   +F      V  GM H+  N IVHRD+   N++
Sbjct: 124 STANDLTARDFFSFALHVARGMAHVANNKIVHRDVAARNVL 2
>31489
          Length = 329

 Score = 30.4 bits (67), Expect = 2.6,   Method: Composition-based stats.
 Identities = 20/91 (21%), Positives = 41/91 (45%), Gaps = 5/91 (5%)
 Frame = +3

Query: 57  EVLKKLNHKNIVKLFAIEEETTTRHKVLIMEFCPCGSLYTVLEEP-----SNAYGLPESE 111
           ++LK   H NI+ +  I +   + H     +F     ++ ++E        +   L E  
Sbjct: 6   KILKHFKHDNIISIREILKPKDSYH-----DFKDIHVVFDLMESDLHRIIYSDQPLTEEH 170

Query: 112 FLIVLRDVVGGMNHLRENGIVHRDIKPGNIM 142
               L  ++ G+ ++    +VHRD+KP N++
Sbjct: 171 IRYFLYQILRGLKYIHSANVVHRDLKPSNLL 263
>26009
          Length = 886

 Score = 29.6 bits (65), Expect = 4.4,   Method: Compositional matrix adjust.
 Identities = 10/28 (35%), Positives = 19/28 (67%)
 Frame = +3

Query: 115 VLRDVVGGMNHLRENGIVHRDIKPGNIM 142
           V++ +V  ++ +    +VHRDIKP N++
Sbjct: 726 VMKQLVSALDFMHSKQLVHRDIKPENVL 809
>38560
          Length = 479

 Score = 29.3 bits (64), Expect = 5.5,   Method: Composition-based stats.
 Identities = 11/23 (47%), Positives = 14/23 (60%)
 Frame = -3

Query: 199 GATVDLWSVGVTFYHAATGSLPF 221
           G+  D+WS+GV  Y    G LPF
Sbjct: 348 GSEADIWSMGVLLYALLCGYLPF 280
>16350
          Length = 1108

 Score = 29.3 bits (64), Expect = 6.3,   Method: Compositional matrix adjust.
 Identities = 11/29 (37%), Positives = 13/29 (44%)
 Frame = +2

Query: 198 YGATVDLWSVGVTFYHAATGSLPFRPFEG 226
           YG   D+WS     +  ATG   F P  G
Sbjct: 461 YGTPADIWSTACMAFELATGDYLFEPHSG 547
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|40254525|ref|NP_071709.2| tropomyosin 3, gamma [Mus
musculus]
         (284 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

04603                                                                 106   1e-23
29815                                                                  74   6e-14
19700                                                                  66   2e-11
>04603
          Length = 1101

 Score =  106 bits (265), Expect = 1e-23,   Method: Compositional matrix adjust.
 Identities = 68/198 (34%), Positives = 111/198 (56%)
 Frame = -2

Query: 87  SLNRRIQLVEEELDRAQERXXXXXXXXXXXXXXXXXXXRGMKVIENRALKDEEKMELQEI 146
            LNRRI L+EE+L+R++ER                   R  + +EN+    +E++E  E 
Sbjct: 764 GLNRRITLLEEDLERSEERLQTATEKLEEATKAADESERVRRTVENKLFAGDERLEECET 585

Query: 147 QLKEAKHIAEEADRKYEEVARKLVIIEGDXXXXXXXXXXXXSRCREMDEQIRLMDQNLKC 206
            L+ AK  A+E + +Y+E ARKLV +E D             R R++++Q   +  +L+ 
Sbjct: 584 DLRAAKQAAQEWEARYDESARKLVAMESDLERCEERAEVAERRVRDLEDQSHTLTNSLRS 405

Query: 207 LSAAEEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDKLKCTKEE 266
           L   EEK SQ+ED YEE I+ LT +LK+ E+RAE +ER V +L+K ++ +++ L+  +  
Sbjct: 404 LELCEEKASQREDSYEETIRDLTQRLKDHESRAEVSEREVKRLQKLLEQMDEDLEEQRRA 225

Query: 267 HLCTQRMLDQTLLDLNEM 284
           + C Q  +DQ + DL  +
Sbjct: 224 NNCLQEEMDQCIGDLQNL 171
>29815
          Length = 337

 Score = 73.9 bits (180), Expect = 6e-14,   Method: Compositional matrix adjust.
 Identities = 39/78 (50%), Positives = 57/78 (73%)
 Frame = +2

Query: 188 SRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVA 247
           S+C E+DEQ+ ++  N+K LS   ++ SQ+ED YEE I+ LT +LK+ E RA+ AER+V+
Sbjct: 41  SKCYELDEQLHVVGNNIKTLSIQNDQASQREDSYEETIRDLTQRLKDCENRAQEAERTVS 220

Query: 248 KLEKTIDDLEDKLKCTKE 265
           KL+K +D LED+L   KE
Sbjct: 221 KLQKEVDRLEDELLVEKE 274
>19700
          Length = 608

 Score = 66.2 bits (160), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 40/123 (32%), Positives = 64/123 (52%)
 Frame = -1

Query: 85  VASLNRRIQLVEEELDRAQERXXXXXXXXXXXXXXXXXXXRGMKVIENRALKDEEKMELQ 144
           +A LNRRIQL+EE+L+R++ER                   RG +  E +    EE++E  
Sbjct: 386 LAGLNRRIQLLEEDLERSEERLQTATEKLEEASKAADESERGRRTAEKKMFTGEERLEDV 207

Query: 145 EIQLKEAKHIAEEADRKYEEVARKLVIIEGDXXXXXXXXXXXXSRCREMDEQIRLMDQNL 204
           E +L+ AK  A E + +YEEVAR+L +++ D             + RE++E+   +  NL
Sbjct: 206 ETELRTAKQAAREWESRYEEVARRLQVMDHDLGKAEYRADNSERKARELEEESLTLTNNL 27

Query: 205 KCL 207
           + L
Sbjct: 26  RSL 18
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6680229|ref|NP_032278.1| high mobility group box 2
[Mus musculus]
         (210 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

11933                                                                 105   1e-23
33187                                                                  74   4e-14
24607                                                                  52   2e-07
14405                                                                  47   8e-06
21088                                                                  39   0.001
30503                                                                  29   1.6  
04411                                                                  28   2.6  
>11933
          Length = 1516

 Score =  105 bits (262), Expect = 1e-23,   Method: Compositional matrix adjust.
 Identities = 61/159 (38%), Positives = 91/159 (57%)
 Frame = +2

Query: 5   DPNKPRGKMSSYAFFVQTCREEHKKKHPDSSVNFAEFSKKCSERWKTMSAKEKSKFEDLA 64
           D NKP+   S+Y +F+  CRE   K+    S   AEF+K+CS +W+ M   +K  FE+ A
Sbjct: 632 DANKPKRSTSAYXYFLAHCREVSAKQGKTIS-RIAEFTKECSAKWREMGGAQKKPFEESA 808

Query: 65  KSDKARYDREMKNYVXXXXXXXXXXXXXNAPKRPPSAFFLFCSENRPKIKIEHPGLSIGD 124
             DKARYD+EM  Y              N PKRP +A+FLF  + R  IK+++ G+   +
Sbjct: 809 AKDKARYDKEMALY-------KGKSTDPNKPKRPMTAYFLFLGDFR--IKMKNRGVDHKE 961

Query: 125 TAKKLGEMWSEQSAKDKQPYEQKAAKLKEKYEKDIAAYR 163
             +  GE W   SA+DK+PYE+++ +  +KYE ++  YR
Sbjct: 962 ILRLAGEEWRNMSAEDKKPYEKRSVEAGKKYEVEMEEYR 1078
>33187
          Length = 644

 Score = 73.9 bits (180), Expect = 4e-14,   Method: Compositional matrix adjust.
 Identities = 40/103 (38%), Positives = 57/103 (55%), Gaps = 6/103 (5%)
 Frame = +3

Query: 71  YDREMKNYV------XXXXXXXXXXXXXNAPKRPPSAFFLFCSENRPKIKIEHPGLSIGD 124
           Y++EM+NYV                   NAPKR  SAFF FC++ R K+K  +P   +GD
Sbjct: 6   YEQEMQNYVPPKGTVVGRGKKRKQIKDPNAPKRSLSAFFWFCNDERNKVKALNPEFGVGD 185

Query: 125 TAKKLGEMWSEQSAKDKQPYEQKAAKLKEKYEKDIAAYRAKGK 167
            AK+LG  WS+   + KQ YE  A + K +YE+++  Y+  GK
Sbjct: 186 IAKELGRKWSDVDPEVKQKYESMAERDKARYEREMTEYKTSGK 314

 Score = 50.4 bits (119), Expect = 5e-07,   Method: Compositional matrix adjust.
 Identities = 25/74 (33%), Positives = 43/74 (58%)
 Frame = +3

Query: 5   DPNKPRGKMSSYAFFVQTCREEHKKKHPDSSVNFAEFSKKCSERWKTMSAKEKSKFEDLA 64
           DPN P+  +S++ +F    R + K  +P+  V   + +K+   +W  +  + K K+E +A
Sbjct: 84  DPNAPKRSLSAFFWFCNDERNKVKALNPEFGV--GDIAKELGRKWSDVDPEVKQKYESMA 257

Query: 65  KSDKARYDREMKNY 78
           + DKARY+REM  Y
Sbjct: 258 ERDKARYEREMTEY 299
>24607
          Length = 1354

 Score = 51.6 bits (122), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 22/66 (33%), Positives = 37/66 (56%)
 Frame = -2

Query: 96  KRPPSAFFLFCSENRPKIKIEHPGLSIGDTAKKLGEMWSEQSAKDKQPYEQKAAKLKEKY 155
           +R P+A+ L+C+  RPK+  E PG+     ++ LG MW   S K+K  + +K+ K+  K 
Sbjct: 393 RRAPTAYMLYCNSQRPKVVAESPGIDFAQISRTLGVMWQCLSKKEKMMWRRKSKKMAGKG 214

Query: 156 EKDIAA 161
              I+ 
Sbjct: 213 STLIST 196
>14405
          Length = 600

 Score = 46.6 bits (109), Expect = 8e-06,   Method: Compositional matrix adjust.
 Identities = 15/38 (39%), Positives = 24/38 (63%)
 Frame = -2

Query: 96  KRPPSAFFLFCSENRPKIKIEHPGLSIGDTAKKLGEMW 133
           +R P+A+ L+C+  RPK+  E PG+     ++ LG MW
Sbjct: 254 RRAPTAYMLYCNSQRPKVVAESPGIDFAQISRTLGVMW 141
>21088
          Length = 490

 Score = 39.3 bits (90), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 26/95 (27%), Positives = 45/95 (47%)
 Frame = -3

Query: 93  NAPKRPPSAFFLFCSENRPKIKIEHPGLSIGDTAKKLGEMWSEQSAKDKQPYEQKAAKLK 152
            A KRP +AF +F    R ++    P L     +K LG++W +     + PY+Q A  LK
Sbjct: 335 GAVKRPMNAFMVFAKMERRQMMAAQPELHNARISKHLGDVWRQCPQPLQDPYKQLAQCLK 156

Query: 153 EKYEKDIAAYRAKGKSEAGKKGPGRPTGSKKKNEP 187
           + + ++   Y+ + +     +GP   T  K  + P
Sbjct: 155 DLHRQEHPEYKYQPRKGRRLQGPLCVTILKMPSRP 51
>30503
          Length = 739

 Score = 28.9 bits (63), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 39/180 (21%), Positives = 71/180 (39%), Gaps = 29/180 (16%)
 Frame = +1

Query: 13  MSSYAFFVQTCREEHKKKHPDSSVNFAEFSKKCSERWKTMSAKEKSKFEDLAKSDKARYD 72
           ++ Y  F+++    + +KHP+  +   E  KK   ++  +SA++K K+   A +    +D
Sbjct: 16  LTPYNMFLKSKMPPYLQKHPE--LPRIEVQKKMKAKYMKLSAEKKKKWIQKAHNAVPEFD 189

Query: 73  REMKNYVX----------------------------XXXXXXXXXXXXNAPKRPP-SAFF 103
            E++ Y                                          +AP +PP SAF 
Sbjct: 190 EEVRQYQVYHPDYEPPAKKVRLTKEEAVLNGDDDGHTTSTGSKKSKFPDAPAKPPISAFH 369

Query: 104 LFCSENRPKIKIEHPGLSIGDTAKKLGEMWSEQSAKDKQPYEQKAAKLKEKYEKDIAAYR 163
           L+      K K       + D    LG  W +   K  + Y +K AKL+ +YE+D+  ++
Sbjct: 370 LYV-----KKKFGDMXGXMKDKMTVLGVHWKQLGPKQDK-YCKKLAKLRLQYEQDLEKFK 531
>04411
          Length = 1247

 Score = 28.1 bits (61), Expect = 2.6,   Method: Compositional matrix adjust.
 Identities = 8/42 (19%), Positives = 22/42 (52%)
 Frame = +1

Query: 37  NFAEFSKKCSERWKTMSAKEKSKFEDLAKSDKARYDREMKNY 78
           N+  + K C + W+++ A +++  E + + D   +   ++ Y
Sbjct: 148 NYTFYDKSCGKIWQSIEALDRAGMEIIERMDPVSFTNYLREY 273
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|9790225|ref|NP_062743.1| calcium binding protein P22
[Mus musculus]
         (195 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

26019                                                                 104   2e-23
16289                                                                  77   6e-15
14594                                                                  54   6e-08
14366                                                                  45   2e-05
05237                                                                  42   1e-04
01019                                                                  35   0.017
14945                                                                  34   0.040
22063                                                                  33   0.058
07385                                                                  30   0.50 
03266                                                                  30   0.55 
22273                                                                  30   0.56 
16255                                                                  30   0.90 
06694                                                                  29   0.96 
20251                                                                  28   2.0  
35350                                                                  28   2.6  
17977                                                                  27   5.2  
11230                                                                  27   6.0  
>26019
          Length = 1561

 Score =  104 bits (260), Expect = 2e-23,   Method: Compositional matrix adjust.
 Identities = 65/169 (38%), Positives = 92/169 (54%), Gaps = 7/169 (4%)
 Frame = +2

Query: 30  RLYSRFTSLDKGENGTLSREDFQRIPELAINPLGDRIINAFFSEGEDQVNFRGFMRTLAH 89
           RL  RF  LD   +G+LS ++F  +PEL  NPL  R+I+ F ++G  +V+F+ F+  ++ 
Sbjct: 101 RLGKRFRKLDLDNSGSLSIDEFMSLPELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGISQ 280

Query: 90  FRPIEDNEKSKDVNGPEPLNSRSNKLHFAFRLYDLDKDDKISRDELLQVLRMMVGVNISD 149
           F    D E               +KL FAF++YD+DKD  IS  EL QVL+MMVG N+ D
Sbjct: 281 FSVKGDKE---------------SKLRFAFKIYDMDKDGYISNGELFQVLKMMVGNNLKD 415

Query: 150 EQLGSIADR-------TIQEADQDGDSAISFTEFVKVLEKVDVEQKMSI 191
            QL  I D+       T+ E        ISF EF  V+  +DV +KM +
Sbjct: 416 TQLQQIVDKPSSMRTPTVME--------ISFEEFCAVVGTMDVHKKMVV 538
>16289
          Length = 522

 Score = 76.6 bits (187), Expect = 6e-15,   Method: Compositional matrix adjust.
 Identities = 39/62 (62%), Positives = 46/62 (74%)
 Frame = +3

Query: 134 ELLQVLRMMVGVNISDEQLGSIADRTIQEADQDGDSAISFTEFVKVLEKVDVEQKMSIRF 193
           ELL +L MMVG NIS +QL SIA+RTI EAD      ISF +F K LE+ DV+QKMSIRF
Sbjct: 3   ELLSILHMMVGANISQDQLVSIAERTILEADLCCQGKISFEDFCKALERTDVDQKMSIRF 182

Query: 194 LH 195
           L+
Sbjct: 183 LN 188
>14594
          Length = 1014

 Score = 53.5 bits (127), Expect = 6e-08,   Method: Compositional matrix adjust.
 Identities = 44/158 (27%), Positives = 75/158 (47%), Gaps = 4/158 (2%)
 Frame = +3

Query: 27  QITRLYSRFTSLDKGENGTLSREDFQRIP-ELAINPLGDRI---INAFFSEGEDQVNFRG 82
           Q+      F+  DK  +GT++  +   +   L  NP  + +   IN   ++G   ++F  
Sbjct: 435 QVAEFKEAFSLFDKDGDGTITTSELGTVMRSLGQNPTENELQDMINEVDADGNGTIDFEE 614

Query: 83  FMRTLAHFRPIEDNEKSKDVNGPEPLNSRSNKLHFAFRLYDLDKDDKISRDELLQVLRMM 142
           F+  +A         K KD +  E L         AFR++D D +  IS  EL  V+  +
Sbjct: 615 FLHMMAR--------KMKDTDCEEELRE-------AFRVFDKDGNGYISAAELRHVMTNL 749

Query: 143 VGVNISDEQLGSIADRTIQEADQDGDSAISFTEFVKVL 180
            G  ++DE++    D  I+EAD DGD  +++ EFV ++
Sbjct: 750 -GEKLTDEEV----DEMIKEADLDGDGMVNYEEFVTMM 848
>14366
          Length = 499

 Score = 45.4 bits (106), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 28/70 (40%), Positives = 43/70 (61%)
 Frame = -3

Query: 112 SNKLHFAFRLYDLDKDDKISRDELLQVLRMMVGVNISDEQLGSIADRTIQEADQDGDSAI 171
           S+ L  AFR++D + +  I+  EL  VL  + G  +SDE++    D  I+EAD  GD  +
Sbjct: 254 SDNLREAFRIFDKEGNGMINAAELRHVLTHL-GEKLSDEEV----DEMIREADISGDGQV 90

Query: 172 SFTEFVKVLE 181
           S+ +FVKV+E
Sbjct: 89  SYNDFVKVME 60
>05237
          Length = 472

 Score = 42.4 bits (98), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 26/68 (38%), Positives = 43/68 (63%)
 Frame = +3

Query: 113 NKLHFAFRLYDLDKDDKISRDELLQVLRMMVGVNISDEQLGSIADRTIQEADQDGDSAIS 172
           ++L  AFR++D D +  IS  EL  V+  + G  ++DE++    D  I+EAD DGD  ++
Sbjct: 27  DELREAFRVFDKDGNGFISASELRHVMTNL-GEKLTDEEV----DEMIREADIDGDGQVN 191

Query: 173 FTEFVKVL 180
           + EFVK++
Sbjct: 192 YEEFVKMM 215
>01019
          Length = 1705

 Score = 35.0 bits (79), Expect = 0.017,   Method: Compositional matrix adjust.
 Identities = 25/72 (34%), Positives = 41/72 (56%), Gaps = 2/72 (2%)
 Frame = +1

Query: 111 RSNKLHFAFRLYDLDKDDK--ISRDELLQVLRMMVGVNISDEQLGSIADRTIQEADQDGD 168
           RS+ ++  + L   DKD    IS  EL  V+  + G  ++DE++    D  I+EAD DGD
Sbjct: 7   RSSGINAEWPLLVFDKDGNGFISAAELRHVMTNL-GEKLTDEEV----DEMIREADIDGD 171

Query: 169 SAISFTEFVKVL 180
             +++ EFV ++
Sbjct: 172 GQVNYEEFVTMM 207
>14945
          Length = 1337

 Score = 33.9 bits (76), Expect = 0.040,   Method: Compositional matrix adjust.
 Identities = 26/75 (34%), Positives = 42/75 (56%)
 Frame = +2

Query: 111 RSNKLHFAFRLYDLDKDDKISRDELLQVLRMMVGVNISDEQLGSIADRTIQEADQDGDSA 170
           RS KL     +    K  KIS   L +V + + G N++DE+L  + D    EAD+DGD  
Sbjct: 335 RS*KLSVCLTMM---KPAKISFRNLKRVAKEL-GENLTDEELQEMID----EADRDGDGE 490

Query: 171 ISFTEFVKVLEKVDV 185
           I+  EF+++++K  +
Sbjct: 491 INQEEFLRIMKKTSL 535
>22063
          Length = 688

 Score = 33.5 bits (75), Expect = 0.058,   Method: Compositional matrix adjust.
 Identities = 16/43 (37%), Positives = 29/43 (67%)
 Frame = +1

Query: 143 VGVNISDEQLGSIADRTIQEADQDGDSAISFTEFVKVLEKVDV 185
           +G N++DE+L  + D    EAD+DGD  I+  EF+++++K  +
Sbjct: 478 LGENLTDEELQEMID----EADRDGDGEINQEEFLRIMKKTSL 594
>07385
          Length = 1292

 Score = 30.4 bits (67), Expect = 0.50,   Method: Compositional matrix adjust.
 Identities = 14/34 (41%), Positives = 24/34 (70%)
 Frame = +3

Query: 147 ISDEQLGSIADRTIQEADQDGDSAISFTEFVKVL 180
           ++DE++    D  I+EAD DGD  +++ EFVK++
Sbjct: 153 LTDEEV----DEMIREADIDGDGQVNYEEFVKMM 242
>03266
          Length = 758

 Score = 30.0 bits (66), Expect = 0.55,   Method: Compositional matrix adjust.
 Identities = 12/23 (52%), Positives = 14/23 (60%)
 Frame = +3

Query: 99  SKDVNGPEPLNSRSNKLHFAFRL 121
           SK V GP P NS  N LH++  L
Sbjct: 312 SKRVTGPRPFNSXZNXLHYSIML 380
>22273
          Length = 297

 Score = 30.0 bits (66), Expect = 0.56,   Method: Compositional matrix adjust.
 Identities = 12/25 (48%), Positives = 18/25 (72%)
 Frame = +1

Query: 156 ADRTIQEADQDGDSAISFTEFVKVL 180
            D  I+EAD DGD  +++ EFVK++
Sbjct: 1   VDEMIREADIDGDGQVNYEEFVKMM 75
>16255
          Length = 767

 Score = 29.6 bits (65), Expect = 0.90,   Method: Compositional matrix adjust.
 Identities = 14/38 (36%), Positives = 25/38 (65%)
 Frame = -2

Query: 143 VGVNISDEQLGSIADRTIQEADQDGDSAISFTEFVKVL 180
           +G  ++DE++    D  I+EAD DGD  +++ EFV ++
Sbjct: 757 LGEKLTDEEV----DEMIREADIDGDGQVNYEEFVTMM 656
>06694
          Length = 1535

 Score = 29.3 bits (64), Expect = 0.96,   Method: Compositional matrix adjust.
 Identities = 12/23 (52%), Positives = 14/23 (60%)
 Frame = -1

Query: 99   SKDVNGPEPLNSRSNKLHFAFRL 121
            SK V GP P NS  N LH++  L
Sbjct: 1529 SKRVTGPTPFNSSQNLLHYSIML 1461
>20251
          Length = 2203

 Score = 28.5 bits (62), Expect = 2.0,   Method: Compositional matrix adjust.
 Identities = 36/160 (22%), Positives = 60/160 (37%), Gaps = 1/160 (0%)
 Frame = +3

Query: 23  FSHSQITRLYSRFTSLDKGENGTLSREDF-QRIPELAINPLGDRIINAFFSEGEDQVNFR 81
           F  SQI      F  +D+  +G + +ED    +  L  NP   + ++   +     +NF 
Sbjct: 141 FDQSQIQEFKEAFNMIDQNRDGFIDKEDLGDMLASLGKNPTEGQ-LDEMMNXAPGPINFT 317

Query: 82  GFMRTLAHFRPIEDNEKSKDVNGPEPLNSRSNKLHFAFRLYDLDKDDKISRDELLQVLRM 141
            F+                 +NG +P +   N    AF  +D D    I  D L ++L  
Sbjct: 318 MFLTMFGD-----------KLNGTDPEDVIKN----AFACFDEDGKGVIQEDRLRELLTT 452

Query: 142 MVGVNISDEQLGSIADRTIQEADQDGDSAISFTEFVKVLE 181
           M      DE      D  I+  + D      + EF ++L+
Sbjct: 453 MGDRFTDDEVDEMFRDAPIKRGNFD------YLEFTRILK 554
>35350
          Length = 339

 Score = 28.1 bits (61), Expect = 2.6,   Method: Compositional matrix adjust.
 Identities = 16/43 (37%), Positives = 21/43 (48%)
 Frame = +2

Query: 141 MMVGVNISDEQLGSIADRTIQEADQDGDSAISFTEFVKVLEKV 183
           MM  +      LG    + I E D+D DS ISF EF+ +  K 
Sbjct: 23  MMEKLGAPQTHLG--LKKMIAEVDEDHDSKISFREFLLIYRKA 145
>17977
          Length = 445

 Score = 26.9 bits (58), Expect = 5.2,   Method: Compositional matrix adjust.
 Identities = 18/64 (28%), Positives = 29/64 (45%), Gaps = 1/64 (1%)
 Frame = +3

Query: 118 AFRLYDLDKDDKISRDELLQVLRMM-VGVNISDEQLGSIADRTIQEADQDGDSAISFTEF 176
           AFR YD D   KI  D+L +  R   V +++       + ++     D++ D  I + EF
Sbjct: 234 AFRFYDKDGKGKIDIDDLREACRKFDVPIDV------WLLEQVFDYCDENRDGQIDYLEF 395

Query: 177 VKVL 180
              L
Sbjct: 396 ANFL 407
>11230
          Length = 747

 Score = 26.6 bits (57), Expect = 6.0,   Method: Compositional matrix adjust.
 Identities = 14/41 (34%), Positives = 21/41 (51%)
 Frame = +3

Query: 109 NSRSNKLHFAFRLYDLDKDDKISRDELLQVLRMMVGVNISD 149
           ++R+   H  F     DKD K+S DE+L    + VG   +D
Sbjct: 465 HARAESKHLIFEADGGDKDGKLSYDEILDKYDLFVGSQATD 587
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|119120859|ref|NP_700448.2| synaptic nuclear envelope
1 isoform 1 [Mus musculus]
         (1431 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

19002                                                                 107   3e-23
29446                                                                  91   4e-18
05733                                                                  59   1e-08
19147                                                                  57   4e-08
09100                                                                  47   4e-05
09711                                                                  45   2e-04
17613                                                                  44   5e-04
32088                                                                  42   0.001
32371                                                                  31   0.019
34417                                                                  37   0.056
04951                                                                  33   1.1  
25483                                                                  30   5.5  
>19002
          Length = 842

 Score =  107 bits (268), Expect = 3e-23,   Method: Compositional matrix adjust.
 Identities = 85/306 (27%), Positives = 133/306 (43%), Gaps = 18/306 (5%)
 Frame = -2

Query: 59  DGIKLLALLEVLSGQKLPCEQGHRVKRIHAVANIGTALKFLEGRKSMYRGSPIKLVNINA 118
           DG  L+ LLEV    ++  +   ++ RIH + N+  AL FL  ++       + L N+ A
Sbjct: 841 DGKMLMKLLEVRVRGEIASDXKGKM-RIHCLENVDKALTFLHEQR-------VHLENMGA 686

Query: 119 TDIADGRPSIVLGLMWTIILYFQIEEXXXXXXXXXXXXXXXXXXXXXXXTETASPPSKRK 178
            DI DG   + LGL+WTIIL FQI++                       +ET S      
Sbjct: 685 HDIVDGSSRLTLGLIWTIILRFQIQDIMIEEVDN---------------SETKS------ 569

Query: 179 VAAKIQGNAKKTLLKWVQHTAGKQMGIEVKDFGKSWRTGLAFHSVIHAIQPELVDLEKVK 238
                   AK  LL W Q        + V++F  SWR GLAF+++IH  +P+LV  +++ 
Sbjct: 568 --------AKDALLLWCQMKTAGYPNVNVRNFTTSWRDGLAFNAIIHKHRPDLVQYDRLH 413

Query: 239 TRSNRENLEDAFTIAETQLGIPRXXXXXXXXXXXXXXXSIMTYVAQFLTQYPDIHGAGCD 298
             S  +NL++AFT+AE +LG+                 SI+TYV  +   +  +      
Sbjct: 412 KSSAIQNLQNAFTVAEDKLGLTALLEPEDVNVEYPDEKSIITYVVTYYHYFSKMKADSVQ 233

Query: 299 GQEDDR-DDRLILKETKV------------WIEQF-----ERDFTRAQMTESSLQDKYQA 340
           G+   +  D  I  E  +            WIEQ      +R F  +    + +Q +  A
Sbjct: 232 GKRIGKVIDNAINTENSIEEYETLTSDLLEWIEQTIVILRDRQFANSL---TGVQQQLAA 62

Query: 341 FKHFRV 346
           F  +R+
Sbjct: 61  FNTYRI 44
>29446
          Length = 1445

 Score = 90.5 bits (223), Expect = 4e-18,   Method: Compositional matrix adjust.
 Identities = 52/134 (38%), Positives = 79/134 (58%), Gaps = 1/134 (0%)
 Frame = +3

Query: 10   SHRDITNVMQRLQDEQ-EIVQKRTFTKWINSHLAKRKPPMVVDDLFEDMKDGIKLLALLE 68
            + RD +   +  +D Q +I+QK TFT+W N HL  R     + DL  D  DG++L+AL+E
Sbjct: 942  TRRDASTERELAEDAQWKIIQKNTFTRWANEHL--RTVNKAIADLESDFSDGLRLVALIE 1115

Query: 69   VLSGQKLPCEQGHRVKRIHAVANIGTALKFLEGRKSMYRGSPIKLVNINATDIADGRPSI 128
            VLSG+K          R   + N+   LKFLE  +       I++VNI++TDI D +  +
Sbjct: 1116 VLSGKKFKHVNKRPNFRTQKLENVTLTLKFLEDDEG------IRIVNIDSTDIVDKKLKL 1277

Query: 129  VLGLMWTIILYFQI 142
            +LGL+WT+IL++ I
Sbjct: 1278 ILGLIWTLILHYSI 1319
>05733
          Length = 1021

 Score = 59.3 bits (142), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 31/99 (31%), Positives = 51/99 (51%), Gaps = 3/99 (3%)
 Frame = +2

Query: 190 TLLKWVQHT--AGKQMGIEVKDFGKSWRTGLAFHSVIHAIQPELVDLEKVKTRSNRENLE 247
           +LL+W Q     G   G+ + DF  SWR+GLAF ++IHA +P L+    +      +N +
Sbjct: 467 SLLRWCQRVLNXGTYRGVHIIDFTSSWRSGLAFCALIHAFRPHLISPASLMECETVKNNQ 646

Query: 248 DAFTIAETQLGI-PRXXXXXXXXXXXXXXXSIMTYVAQF 285
            AF +A+ +LGI P                +++ Y++QF
Sbjct: 647 LAFDVAQKELGIAPVMRGEDMAACAVPDKLTMVAYLSQF 763
>19147
          Length = 474

 Score = 57.4 bits (137), Expect = 4e-08,   Method: Compositional matrix adjust.
 Identities = 38/132 (28%), Positives = 56/132 (42%)
 Frame = +1

Query: 102 RKSMYRGSPIKLVNINATDIADGRPSIVLGLMWTIILYFQIEEXXXXXXXXXXXXXXXXX 161
           R S      +KLV+I A +I DG   + LG++WTIIL F I++                 
Sbjct: 40  RWSYIASKGVKLVSIGAEEIVDGNVKMTLGMIWTIILRFAIQDITVEEL----------- 186

Query: 162 XXXXXXTETASPPSKRKVAAKIQGNAKKTLLKWVQHTAGKQMGIEVKDFGKSWRTGLAFH 221
                                    AK+ LL W Q        + V++F  S++ GLAF 
Sbjct: 187 ------------------------TAKEGLLLWCQRKTAPYKNVNVQNFHLSFKDGLAFC 294

Query: 222 SVIHAIQPELVD 233
           ++IH  +PEL+D
Sbjct: 295 ALIHRHRPELID 330
>09100
          Length = 930

 Score = 47.4 bits (111), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 28/113 (24%), Positives = 54/113 (47%)
 Frame = +1

Query: 29  QKRTFTKWINSHLAKRKPPMVVDDLFEDMKDGIKLLALLEVLSGQKLPCEQGHRVKRIHA 88
           Q   +  WINS L K+    +++DL  DM+DG+    ++ ++S Q++P  Q         
Sbjct: 463 QLSAYMAWINSQLKKKPGAHLIEDLRHDMRDGVVFADVIHIVSKQQIPGIQNVPTTLDEM 642

Query: 89  VANIGTALKFLEGRKSMYRGSPIKLVNINATDIADGRPSIVLGLMWTIILYFQ 141
             N+   L F+   +       IK+  I++ DI +G    V+ L+  +  +++
Sbjct: 643 RQNVDRVLHFMTQNR-------IKMHRISSRDIVEGNLKAVMRLILALAAHYK 780
>09711
          Length = 3041

 Score = 45.1 bits (105), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 37/129 (28%), Positives = 52/129 (40%), Gaps = 20/129 (15%)
 Frame = +1

Query: 29  QKRTFTKWINSHLA-----KRKPPMVVDD--LFEDMKDGIKLLALLEVLSGQKLPCEQGH 81
           +++ F +WIN HL+     K   P+  D   LF  M DG+ L  L+              
Sbjct: 52  EQKAFAEWINRHLSDXPDCKHLLPLDADGTQLFGQMADGVLLCKLIN------------- 192

Query: 82  RVKRIHAVANIGTALKFLEGRKSMYR-------------GSPIKLVNINATDIADGRPSI 128
                H+V+N        +   S+YR                   VNI   D+A GRP +
Sbjct: 193 -----HSVSNTIDERTINKQNLSLYRRHENLTLAVNSAGAIGCTTVNIGPEDLAAGRPHL 357

Query: 129 VLGLMWTII 137
           VLGL+W II
Sbjct: 358 VLGLLWQII 384

 Score = 37.7 bits (86), Expect = 0.035,   Method: Compositional matrix adjust.
 Identities = 47/244 (19%), Positives = 89/244 (36%), Gaps = 11/244 (4%)
 Frame = +1

Query: 29   QKRTFTKWINSHLAKRKPPMVVDDLFEDMKDGIKLLALLEVL-----------SGQKLPC 77
            +++T+  W+NS      P   V  L+ D+ DG+ +  L + +                  
Sbjct: 850  EEKTYRNWMNS--LGVSP--FVHHLYSDLYDGLIIFQLYDYIQPGLVDWSKVKKKFNKLK 1017

Query: 78   EQGHRVKRIHAVANIGTALKFLEGRKSMYRGSPIKLVNINATDIADGRPSIVLGLMWTII 137
             +  R++  +    +G  +K ++          +KLV I   DI DG P + LGL+W ++
Sbjct: 1018 ARFERIENCNYAVELGPQVKLVK----------VKLVGIAGQDILDGNPVLTLGLVWQLM 1167

Query: 138  LYFQIEEXXXXXXXXXXXXXXXXXXXXXXXTETASPPSKRKVAAKIQGNAKKTLLKWVQH 197
              + +                         TE   P S  ++   +    KK        
Sbjct: 1168 RAYTL-------------------AILSKITENNKPISDNEIITWVNSKIKKD-----DR 1275

Query: 198  TAGKQMGIEVKDFGKSWRTGLAFHSVIHAIQPELVDLEKVKTRSNRENLEDAFTIAETQL 257
             +G Q         +    G+    VI AI+P +V+ + +   +   + +D  T A   +
Sbjct: 1276 ISGFQ--------DRKLNDGVIVARVIEAIKPGIVNWDNIDCSA--RDYQDRLTNARYAI 1425

Query: 258  GIPR 261
            G+ R
Sbjct: 1426 GLAR 1437
>17613
          Length = 1108

 Score = 43.9 bits (102), Expect = 5e-04,   Method: Composition-based stats.
 Identities = 22/56 (39%), Positives = 33/56 (58%)
 Frame = +1

Query: 205 IEVKDFGKSWRTGLAFHSVIHAIQPELVDLEKVKTRSNRENLEDAFTIAETQLGIP 260
           + V++F  S++ GLAF ++IH  +PEL+D   +   +  ENL  AF IAE     P
Sbjct: 241 VNVQNFHLSFKDGLAFCALIHRHRPELIDYHSLSKDNPLENLNTAFDIAENTWTSP 408

 Score = 40.0 bits (92), Expect(2) = 0.002,   Method: Composition-based stats.
 Identities = 17/34 (50%), Positives = 25/34 (73%)
 Frame = +2

Query: 111 IKLVNINATDIADGRPSIVLGLMWTIILYFQIEE 144
           +KLV+I A +I DG   + LG++WTIIL F I++
Sbjct: 65  VKLVSIGAEEIVDGNVKMTLGMIWTIILRFAIQD 166

 Score = 20.8 bits (42), Expect(2) = 0.002,   Method: Composition-based stats.
 Identities = 8/26 (30%), Positives = 16/26 (61%), Gaps = 3/26 (11%)
 Frame = +1

Query: 85  RIHAVANIGTALKFLE---GRKSMYR 107
           R H +AN+  AL +++   G+  ++R
Sbjct: 7   RFHKIANVNKALDYIDLQRGQTGLHR 84
>32088
          Length = 1928

 Score = 42.4 bits (98), Expect = 0.001,   Method: Composition-based stats.
 Identities = 39/129 (30%), Positives = 54/129 (41%), Gaps = 20/129 (15%)
 Frame = +1

Query: 29   QKRTFTKWINSHLAKR---KPPMVV----DDLFEDMKDGIKLLALLEVLSGQKLPCEQGH 81
            +++ F  WIN HL      K  M V    DDLF+ + DGI L  L+              
Sbjct: 1264 EQKAFAAWINRHLKDDPDCKHLMEVNEEGDDLFKKVGDGILLCKLIN------------- 1404

Query: 82   RVKRIHAVANIGTALKFLEGRKSMY-RGSPIKL------------VNINATDIADGRPSI 128
                 H+V+N        +   ++Y R   + L            VNI   D+A GRP +
Sbjct: 1405 -----HSVSNTIDERAINKSNLNVYHRHENLTLAVNSAGSIGCTTVNIGPEDLAAGRPHL 1569

Query: 129  VLGLMWTII 137
            VLGL+W II
Sbjct: 1570 VLGLLWQII 1596
>32371
          Length = 625

 Score = 31.2 bits (69), Expect(2) = 0.019,   Method: Composition-based stats.
 Identities = 11/21 (52%), Positives = 16/21 (76%)
 Frame = -1

Query: 205 IEVKDFGKSWRTGLAFHSVIH 225
           +++KD   SWR GLAF ++IH
Sbjct: 622 VDIKDLLVSWRNGLAFCAIIH 560

 Score = 26.6 bits (57), Expect(2) = 0.019,   Method: Compositional matrix adjust.
 Identities = 12/32 (37%), Positives = 19/32 (59%)
 Frame = -2

Query: 229 PELVDLEKVKTRSNRENLEDAFTIAETQLGIP 260
           P+L+D + +   +   N   AFT+AE +L IP
Sbjct: 549 PDLIDYDSLSKENVLYNNNLAFTVAEQELDIP 454
>34417
          Length = 1096

 Score = 37.0 bits (84), Expect = 0.056,   Method: Composition-based stats.
 Identities = 23/79 (29%), Positives = 32/79 (40%), Gaps = 1/79 (1%)
 Frame = +2

Query: 214 WRTGLAFHSVIHAIQPELVDLEKVKTRSNRENLEDAFTIAETQLGI-PRXXXXXXXXXXX 272
           W  GLAF ++IH   P+  D  +++ ++ R N E AF  AE    I P            
Sbjct: 47  WNNGLAFCALIHHFYPDAFDYSQLQPQNRRYNFELAFDTAEKLADISPLLDVEDMIKMKN 226

Query: 273 XXXXSIMTYVAQFLTQYPD 291
                + TYV  F     D
Sbjct: 227 PDWKCVFTYVQSFYRHLRD 283
>04951
          Length = 2852

 Score = 32.7 bits (73), Expect = 1.1,   Method: Composition-based stats.
 Identities = 13/27 (48%), Positives = 18/27 (66%)
 Frame = +1

Query: 111 IKLVNINATDIADGRPSIVLGLMWTII 137
           +KLV I   DI DG P + LGL+W ++
Sbjct: 61  MKLVGIGGKDIHDGNPVLTLGLVWQLM 141
>25483
          Length = 438

 Score = 30.4 bits (67), Expect = 5.5,   Method: Compositional matrix adjust.
 Identities = 34/120 (28%), Positives = 56/120 (46%), Gaps = 4/120 (3%)
 Frame = -2

Query: 649 AMNDAGNFLIETCDEIVSRDLKQQLLLLNGRWRELFMEV---KQYA-RADEMDRMKKEYI 704
           +MN AGN ++       +  L+Q+   +N RW+ L  EV   ++YA R +E      ++ 
Sbjct: 410 SMNSAGNEMLRQMSAPQADLLRQRQDSINQRWKALCSEVFERQKYAGRVEEGSTRTSDFT 231

Query: 705 DVTTTLFGFATEAHRKLSEPLEVSFINVKLLIQDLEDLEKRVPVMDAQYKMIAKKAHLFA 764
           D    LF +  E    L+  L       KL  Q L DL ++V   D Q  + +++ +L A
Sbjct: 230 DDMDELFFWIDETENILASTL-------KLETQYLSDLLEKVK--DRQEDVASRQQNLTA 78
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|29244176|ref|NP_808385.1| hypothetical protein
4732456N10 [Mus musculus]
         (538 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

11243                                                                 106   3e-23
02016                                                                  79   4e-15
26996                                                                  46   4e-05
22014                                                                  45   8e-05
15079                                                                  28   8.1  
>11243
          Length = 828

 Score =  106 bits (264), Expect = 3e-23,   Method: Compositional matrix adjust.
 Identities = 71/225 (31%), Positives = 130/225 (57%), Gaps = 1/225 (0%)
 Frame = -2

Query: 241 AENEFVVLKKDVDAAYMNKVELEAKVEALMDEINFLRAFFEAELAQLQAQISETSVVLSM 300
           AE++ V L++ +D   +NK +LE ++E+L +E+ +L+   E ELA +++  +  +V + +
Sbjct: 827 AESDIVGLRRVLDELTLNKTDLELEIESLKEELIYLKKNHEEELAVVRSS-ARGNVDVQV 651

Query: 301 DNNRSLNLDSIIAEVKAQYEDIANRSRAEAESWYQTKYEELQRSAGQRGDDLRTTKMEIS 360
           D+   ++L  I+ +V++QYE +  ++R E E+ Y+ + E L          L+T+K  I+
Sbjct: 650 DSAPPVDLAQIMXDVRSQYESMMEKNRQELEACYKGQSENLNHEVATNTAALQTSKTAIT 471

Query: 361 ELNRAMQRLRSEIDNLKKQCATLQASIADAEQRGELALKDAKNKLAELEDALQKAKQDMA 420
           +L R +Q L  E+ +L      L+ ++A+ E +    L   +  + ++E  LQ  + D  
Sbjct: 470 DLKRTIQSLEIELQSLLSMKGALEGTLAETEAQYGAQLNHLQAMITQVEMELQNLRSDAD 291

Query: 421 RQLREYQELMNVKLALDIEIATYRKLLEGEECRLT-GEGVGAVNI 464
            Q  EY+ L++ K  L++EIATYR+LLEGE+ R +  E   AV I
Sbjct: 290 HQSLEYKRLLDAKTRLEMEIATYRRLLEGEDTRFSQTETQKAVTI 156
>02016
          Length = 3061

 Score = 79.3 bits (194), Expect = 4e-15,   Method: Compositional matrix adjust.
 Identities = 63/222 (28%), Positives = 119/222 (53%), Gaps = 9/222 (4%)
 Frame = +3

Query: 242 ENEFVVLKKDVDAAYMNKVELEAKVEALMDEINFLRAFFEAEL--AQLQAQISETSVVLS 299
           E +   LKK ++   + +V+LE ++++L +EINF    +E EL  ++++  +    V   
Sbjct: 141 EKQLAKLKKQLEEETLLRVDLENRLQSLKEEINFKSQVYEQELEESRVRTTVEIEQVDGR 320

Query: 300 MDNNRSLNLDSIIAEVKAQYEDIANRSRAEAESWYQTKYEELQRSA-------GQRGDDL 352
           +++     L   + E++AQ+E      R E E+ Y+ K  +L+  A       G   ++L
Sbjct: 321 LEHEYEQRLLEALREIRAQHESDLQTVRVELETLYENKIADLKAQANRSNSASGSAWEEL 500

Query: 353 RTTKMEISELNRAMQRLRSEIDNLKKQCATLQASIADAEQRGELALKDAKNKLAELEDAL 412
           R T+    +L   + +L++E    + + + L++ +A   +R E  L+     LA+ +D L
Sbjct: 501 RITRKRADDLGAELAKLKAETAGFELRISDLESQLA--REREEFRLR-----LAQKDDEL 659

Query: 413 QKAKQDMARQLREYQELMNVKLALDIEIATYRKLLEGEECRL 454
            + +  +  Q++EY +L+++K+ LD EI  YRKLLE EE RL
Sbjct: 660 AELRLTLEEQMQEYSDLLDIKIRLDREIDAYRKLLESEESRL 785
>26996
          Length = 386

 Score = 46.2 bits (108), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 28/86 (32%), Positives = 54/86 (62%), Gaps = 2/86 (2%)
 Frame = -1

Query: 131 EIDPSLQR-VRKEEKEQIKTLNNKFASFIDKVRFLEQQNKVLETKWSLLQE-HKTTRTNL 188
           E  PS  R  R++E+E ++ LN++ A++ID+VRFLE +N  L T+    +E  K   +++
Sbjct: 263 ERPPSPTRSTRQQEQESLQGLNDRLANYIDRVRFLEAENSRLSTQVQSTEEIVKREVSSV 84

Query: 189 EPMFEAYITNLRRQLECLGGERSRLE 214
           + ++E  + + RR L+    E++R++
Sbjct: 83  KNLYETELADARRLLDDTAREKARIQ 6
>22014
          Length = 353

 Score = 45.1 bits (105), Expect = 8e-05,   Method: Compositional matrix adjust.
 Identities = 26/58 (44%), Positives = 39/58 (67%)
 Frame = -1

Query: 399 KDAKNKLAELEDALQKAKQDMARQLREYQELMNVKLALDIEIATYRKLLEGEECRLTG 456
           +D   ++ +L++ + K + +M   L E Q LM+ KL+L++EIA YRKLLE EE R TG
Sbjct: 230 QDHTLEVNQLKEEMNKLRAEMEAMLVELQTLMDAKLSLELEIAAYRKLLETEESR-TG 60
>15079
          Length = 809

 Score = 28.5 bits (62), Expect = 8.1,   Method: Compositional matrix adjust.
 Identities = 16/72 (22%), Positives = 33/72 (45%)
 Frame = -3

Query: 286 QLQAQISETSVVLSMDNNRSLNLDSIIAEVKAQYEDIANRSRAEAESWYQTKYEELQRSA 345
           +  A+  E +V     +NR  N   +    + Q      +SR    +W+ ++Y E  +  
Sbjct: 282 RFDARGQEPTVRRGSISNRKCNYSIVHLFRQ*QSXHSLRKSREGGRAWWGSRYVERGKRV 103

Query: 346 GQRGDDLRTTKM 357
           G+RG  +R+ ++
Sbjct: 102 GERGQSIRSGRV 67
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|209977074|ref|NP_001028778.2| acyl-CoA synthetase
long-chain family member 3 isoform a [Mus musculus]
         (720 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

02291                                                                 106   4e-23
34113                                                                  97   2e-20
03756                                                                  96   4e-20
20450                                                                  59   6e-09
14024                                                                  57   2e-08
26510                                                                  55   9e-08
13327                                                                  46   7e-05
22123                                                                  37   0.029
14264                                                                  33   0.30 
37217                                                                  33   0.44 
01013                                                                  30   3.0  
20248                                                                  30   4.6  
>02291
          Length = 3161

 Score =  106 bits (264), Expect = 4e-23,   Method: Compositional matrix adjust.
 Identities = 95/345 (27%), Positives = 158/345 (45%), Gaps = 16/345 (4%)
 Frame = -1

Query: 278  PSDIAVIMYTSGSTGIPKGVMISHSNIIASI-----TGMARRIPRLGEEDVYIGYLPLAH 332
            P+   V++YTSG+TG PKGVM+SH NI  ++     + M +   + G++   I YLPL+H
Sbjct: 2867 PNKCCVLIYTSGTTGTPKGVMLSHDNITYTVAVNMSSTMQQLNTKFGQQS-GISYLPLSH 2691

Query: 333  VLELSAEL-VCLSHGCRIGYSSPQTLADQSSKIKKGSKGDT-SVLKPTLMAAVPEIMDRI 390
            +     ++ V +  G    ++ P  L        KGS G T   ++P +   VP + +++
Sbjct: 2690 IAAQMMDIYVXIGFGGTTYFAQPDAL--------KGSLGATLREVRPHIFLGVPRVWEKM 2535

Query: 391  YKNVMNKVNEMSAFQRNLFI------LAYNYK-MEQISKGCSTPLCDRFVFXXXXXXXXX 443
             + +      ++  ++ +        L  NY  ME  S     PL +  VF         
Sbjct: 2534 QETMQTAARSVTGMKKKIGAWAKGVGLKANYAIMEGRSPPAXXPLANALVFKKVRGLLGL 2355

Query: 444  XX-XXXXXXXAPLSATTQRFMNICFCCPVGQGYGLTESTGAGTITEVWDYNTGRVGAPLV 502
                      AP++  T  +  +    P+ + YG++E +G  T+          VG  L 
Sbjct: 2354 DRCLMQLSGAAPIAKETLEYF-MSLNVPICEVYGMSECSGPHTVGFPKVNRVNSVGRELN 2178

Query: 503  CCEIKLKNWEEGGYFNTDKPHPRGEILIGGQNVTMGYYKNEAKTKTDFFEDENGQRWLCT 562
             C  +L N +E G          GE+++ G++V MGY  +E KTK +  +D  G   L +
Sbjct: 2177 GCTTELANQDEDG---------NGEVVMHGRHVFMGYLNDEEKTK-EALDDAGG---LHS 2037

Query: 563  GDIGEFDPDGCLKIIDRKKDLVKLQAGEYVSLGKVEAALKN-LPL 606
            GD+G+ D DG L I  R K+L+    GE +    +E  +K  LP+
Sbjct: 2036 GDVGKKDKDGFLFITGRIKELIITAGGENIPPVAIEDRVKEALPV 1902
>34113
          Length = 694

 Score = 97.4 bits (241), Expect = 2e-20,   Method: Compositional matrix adjust.
 Identities = 65/190 (34%), Positives = 105/190 (55%), Gaps = 4/190 (2%)
 Frame = -3

Query: 147 FGNGLQMLGQKP--KANIAIFCETRAEWMIAAQACFMYNFQLVTLYATLGGPAIVHGLNE 204
           FG+GL  LG KP    N  IF +  +EW+IA QAC MY+   V LY TLG  A+ + +N 
Sbjct: 560 FGSGLFALGVKPGQDTNFGIFTQNSSEWVIADQACQMYSMVTVALYDTLGVEAVKYVVNL 381

Query: 205 TEVTNIITSKELLQTKLKDIVSLVPRLRHIITVDGKPPTWSEFPK--GVIVHTMAAVQAL 262
            E+  ++  KE+    L +  S +P L+ I+  +       +  +  GV +   + V+ L
Sbjct: 380 AEIGTVVCDKEVRAKILLEGKSELPCLKLIVMXEEITEELQQKAQRAGVKIIRFSEVEDL 201

Query: 263 GVKANVEKKAHSKPLPSDIAVIMYTSGSTGIPKGVMISHSNIIASITGMARRIPRLGEED 322
           G K N+ +     P PSD+  I +TSG+TG PKGV+++H+N++A+++ +      L +  
Sbjct: 200 G-KKNIREPLL--PKPSDVCTICFTSGTTGNPKGVVLTHANLVANVSSVKV---SLKDTM 39

Query: 323 VYIGYLPLAH 332
           V+I  L + H
Sbjct: 38  VWIQPLLICH 9
>03756
          Length = 992

 Score = 96.3 bits (238), Expect = 4e-20,   Method: Compositional matrix adjust.
 Identities = 60/188 (31%), Positives = 99/188 (52%), Gaps = 8/188 (4%)
 Frame = +2

Query: 132 YNWLSYEDVFIRALDFGNGLQMLGQKPKAN--IAIFCETRAEWMIAAQACFMYNFQLVTL 189
           ++W+SY  V  RA  FG+GL   G +P  +  + I+     EW +A   C MY+   V L
Sbjct: 275 FSWMSYRQVLDRAHCFGSGLISKGVQPSNSSFVGIYSGNCVEWSLADLGCHMYSMVPVPL 454

Query: 190 YATLGGPAIVHGLNETEVTNIITSKELLQTKLKDIVSLVPRLRHIITVDGKPPTWSE--- 246
           Y TLG  A V+ +N+T++  ++        +L +I   VP L+  I   GK  TW +   
Sbjct: 455 YDTLGPQACVYIINQTKLCTVVCDDVNKAKRLLEIADQVPSLKRFI-FTGK--TWPQDIR 625

Query: 247 ---FPKGVIVHTMAAVQALGVKANVEKKAHSKPLPSDIAVIMYTSGSTGIPKGVMISHSN 303
                + V + T   ++++G K   + +    P P D+A + YTSG+TG PKGVM++H+N
Sbjct: 626 DLANERKVELLTFKEIESIGTK---DTRDPIPPKPDDLATLCYTSGTTGDPKGVMLTHAN 796

Query: 304 IIASITGM 311
            +  ++ +
Sbjct: 797 FLIMLSSV 820
>20450
          Length = 775

 Score = 58.9 bits (141), Expect = 6e-09,   Method: Compositional matrix adjust.
 Identities = 40/118 (33%), Positives = 60/118 (50%)
 Frame = -3

Query: 492 YNTGRVGAPLVCCEIKLKNWEEGGYFNTDKPHPRGEILIGGQNVTMGYYKNEAKTKTDFF 551
           Y  G  G P    E K+ + E G     ++    G++   G  +  GY+KN   T     
Sbjct: 644 YELGSCGFPTPNAEFKVIDSETGKCLGVNQ---AGDLYKRGPLIMRGYHKNPQATADTI- 477

Query: 552 EDENGQRWLCTGDIGEFDPDGCLKIIDRKKDLVKLQAGEYVSLGKVEAALKNLPLIDN 609
              + Q WL TGD+G+FD +G L I+DRKK+L+K + GE V+   +E  L + P I +
Sbjct: 476 ---DAQGWLKTGDVGQFDSNGFLYIVDRKKELIKYK-GEQVAPAMLEDVLLSHPGISD 315
>14024
          Length = 655

 Score = 57.4 bits (137), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 40/150 (26%), Positives = 72/150 (48%)
 Frame = +3

Query: 453 APLSATTQRFMNICFCCPVGQGYGLTESTGAGTITEVWDYNTGRVGAPLVCCEIKLKNWE 512
           AP+S  T+++  +     +   +G++E++G  T+ +        +G  L  CE K+ N +
Sbjct: 60  APMSPETKKYF-LSLDMKILDAFGMSETSGCHTLCQPDSTLLNSIGKSLPGCESKIINQD 236

Query: 513 EGGYFNTDKPHPRGEILIGGQNVTMGYYKNEAKTKTDFFEDENGQRWLCTGDIGEFDPDG 572
             G+         GE+ I G++V MGY  N+ KT+    +D     WL +GD+   D  G
Sbjct: 237 ANGH---------GELCIRGRHVFMGYISNKEKTEESLDDD----CWLHSGDLAYIDDKG 377

Query: 573 CLKIIDRKKDLVKLQAGEYVSLGKVEAALK 602
            + +  R K+L+    GE +    +E  +K
Sbjct: 378 YVCLTGRLKELIITAGGENIPPVHIENIIK 467
>26510
          Length = 1692

 Score = 55.1 bits (131), Expect = 9e-08,   Method: Compositional matrix adjust.
 Identities = 37/124 (29%), Positives = 64/124 (51%)
 Frame = +1

Query: 279 SDIAVIMYTSGSTGIPKGVMISHSNIIASITGMARRIPRLGEEDVYIGYLPLAHVLELSA 338
           +D+  + Y+SG+TG+PKGVM+SH NI+A+I    R +     ED  +G LP  H+  L+ 
Sbjct: 697 TDVLFLPYSSGTTGLPKGVMLSHRNIVANILQF-RELANTQPEDRTLGLLPFFHIYGLT- 870

Query: 339 ELVCLSHGCRIGYSSPQTLADQSSKIKKGSKGDTSVLKPTLMAAVPEIMDRIYKNVMNKV 398
              C+  G     +   T+     ++   S  D  +   TL+ AVP ++  + ++ M   
Sbjct: 871 ---CVQFGTLYDGAELVTVPRFEPELFLKSLHDRKI---TLLQAVPPVVLFLARHPMVSQ 1032

Query: 399 NEMS 402
            ++S
Sbjct: 1033FDLS 1044

 Score = 42.0 bits (97), Expect = 8e-04,   Method: Compositional matrix adjust.
 Identities = 38/113 (33%), Positives = 56/113 (49%)
 Frame = +2

Query: 526  GEILIGGQNVTMGYYKNEAKTKTDFFEDENGQRWLCTGDIGEFDPDGCLKIIDRKKDLVK 585
            GE  + G    +GY  N+    TD   D +G  WL TGD+G    DG + I DR K+L+K
Sbjct: 1277 GEYCMDGPQKMLGYLHNQ--QATDDMIDRDG--WLHTGDLGYMREDGMIIIEDRLKELIK 1444

Query: 586  LQAGEYVSLGKVEAALKNLPLIDNICAYANSYHSYVIGFVVPNQKELTELART 638
             + G  V   ++E+ L + P + +         + VIG  +P+Q E  EL R 
Sbjct: 1445 YK-GFQVPPAELESLLLSHPAVQD---------AGVIG--IPDQ-EAGELPRA 1564
>13327
          Length = 549

 Score = 45.8 bits (107), Expect = 7e-05,   Method: Composition-based stats.
 Identities = 24/51 (47%), Positives = 32/51 (62%)
 Frame = +3

Query: 559 WLCTGDIGEFDPDGCLKIIDRKKDLVKLQAGEYVSLGKVEAALKNLPLIDN 609
           WL +GD+G FD DG L I+DRKK+L+K +A E V    +E  L   P I +
Sbjct: 3   WLDSGDVGYFDSDGFLYIVDRKKELIKFKA-EQVPPAMLEDVLLTHPGISD 152
>22123
          Length = 347

 Score = 37.0 bits (84), Expect = 0.029,   Method: Composition-based stats.
 Identities = 34/123 (27%), Positives = 48/123 (39%)
 Frame = +3

Query: 457 ATTQRFMNICFCCPVGQGYGLTESTGAGTITEVWDYNTGRVGAPLVCCEIKLKNWEEGGY 516
           A  QRF   C      QGYG+TE   A   T   +   G  G P    E K+ + E G  
Sbjct: 18  AFYQRFGVRCL-----QGYGMTEYPVASVATPAKN-ELGSCGFPTPNAEFKVIDSETGKC 179

Query: 517 FNTDKPHPRGEILIGGQNVTMGYYKNEAKTKTDFFEDENGQRWLCTGDIGEFDPDGCLKI 576
              ++         G       +++   +            R L TGD+G+FD +G L I
Sbjct: 180 LGVNQAG-------GSLQARTSHHERLPQESPGHRRHH*CSRVLKTGDVGQFDSNGFLYI 338

Query: 577 IDR 579
           +DR
Sbjct: 339 VDR 347
>14264
          Length = 1790

 Score = 33.5 bits (75), Expect = 0.30,   Method: Compositional matrix adjust.
 Identities = 26/98 (26%), Positives = 42/98 (42%)
 Frame = -3

Query: 248  PKGVIVHTMAAVQALGVKANVEKKAHSKPLPSDIAVIMYTSGSTGIPKGVMISHSNIIAS 307
            P G+    M    AL V+   +    S+     I V +YTSG+TG+PK V  +   +   
Sbjct: 1128 PAGMXDLDMLMTDALPVRP--DPSLRSQMTDDTIGVYIYTSGTTGLPKPVYYNQKKLKMF 955

Query: 308  ITGMARRIPRLGEEDVYIGYLPLAHVLELSAELVCLSH 345
             T    ++  +  +D+    LPL H+       + L H
Sbjct: 954  TT--TAQLLDVTTQDIVYTVLPLYHISAFGVGFMGLLH 847
>37217
          Length = 548

 Score = 33.1 bits (74), Expect = 0.44,   Method: Compositional matrix adjust.
 Identities = 32/112 (28%), Positives = 51/112 (45%), Gaps = 1/112 (0%)
 Frame = -2

Query: 453 APLSATTQRFMNICFCCP-VGQGYGLTESTGAGTITEVWDYNTGRVGAPLVCCEIKLKNW 511
           APLS  T+  +      P + QGYGL+EST +  +        G V    V    K+ + 
Sbjct: 313 APLSRETEDQIKERLGIPFIRQGYGLSESTLSVLVQNDEHCKPGSVXVLNVGVYAKVIDP 134

Query: 512 EEGGYFNTDKPHPRGEILIGGQNVTMGYYKNEAKTKTDFFEDENGQRWLCTG 563
           + G +   ++   RGE+   G  +  GY  ++  T+T     ++G  WL TG
Sbjct: 133 DTGKHLGANE---RGELCFKGPGIMKGYIGDKRSTQTTI---KDG--WLHTG 2
>01013
          Length = 514

 Score = 30.0 bits (66), Expect = 3.0,   Method: Composition-based stats.
 Identities = 13/37 (35%), Positives = 21/37 (56%)
 Frame = +1

Query: 5   VSSTPSTMKLKQTINPILLYFIHFIISLYTILTYIPF 41
           V++ PS ++ K  +  +L+YF  F I   +I   IPF
Sbjct: 397 VANNPSLIETKTILTNVLIYFTRFNIRRSSIFANIPF 507
>20248
          Length = 607

 Score = 29.6 bits (65), Expect = 4.6,   Method: Composition-based stats.
 Identities = 18/62 (29%), Positives = 32/62 (51%), Gaps = 2/62 (3%)
 Frame = +3

Query: 312 ARRIPRLGEEDVYIG--YLPLAHVLELSAELVCLSHGCRIGYSSPQTLADQSSKIKKGSK 369
           AR +P +  + ++IG   LP+ H + +S+    +SH C       QT+  Q+   K+  K
Sbjct: 291 ARLLPVI--QQIHIGERQLPVIHQIHISSHQDRVSHTCLKAIHWTQTIGSQTGLRKRAQK 464

Query: 370 GD 371
           G+
Sbjct: 465 GE 470
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6671495|ref|NP_031404.1| ATP-binding cassette,
sub-family A, member 4 [Mus musculus]
         (2310 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

26534                                                                 107   4e-23
27295                                                                  99   2e-21
01623                                                                  74   5e-13
26643                                                                  69   2e-11
05764                                                                  62   3e-09
20400                                                                  61   6e-09
34140                                                                  60   9e-09
02301                                                                  57   8e-08
22529                                                                  44   0.001
30281                                                                  43   0.002
20290                                                                  37   0.14 
03538                                                                  37   0.14 
22801                                                                  34   0.71 
33849                                                                  33   1.7  
18248                                                                  32   2.4  
38795                                                                  30   9.0  
06007                                                                  30   9.2  
>26534
          Length = 931

 Score =  107 bits (268), Expect = 4e-23,   Method: Compositional matrix adjust.
 Identities = 92/329 (27%), Positives = 137/329 (41%), Gaps = 32/329 (9%)
 Frame = +1

Query: 1113 IIMSTHHMDEADLLGDRIAIISQGRLYCSGTPLFLKNCFGTGFYLTLVRKMKNIQSQRGG 1172
            +++STH MDEADLLGDRIAI+++G + C GT +FLK  +G G+++ +V+           
Sbjct: 13   LLLSTHFMDEADLLGDRIAIMAEGVVKCCGTSMFLKKLYGAGYHMVMVK----------- 159

Query: 1173 CEGVCSCTSKGFSTRCPTRVDEITEEQVLDGDVQELMDLVYHHVPEAKLVECIGQELIFL 1232
                          +C               DV  +   V   +P A+L   IG EL FL
Sbjct: 160  ------------GPQC---------------DVATVTAAVQAQLPGAQLESEIGAELSFL 258

Query: 1233 LPNKNFKQRAYASLFRELEETLADLGLSSFGISDTPLEEIFLKV------TEDAG----- 1281
            LP +   +  +A LFR +E    +LG++SFG + T +EE+FLKV       ED G     
Sbjct: 259  LPEEEAPK--FADLFRVMESQSDELGITSFGATATTMEEVFLKVGASGVSEEDNGRVQSL 432

Query: 1282 -------AGSMFVGGAQQKREQAGLRHPCSAPTEKLRQYAQAPHTCSPGQVDPPKGQPSP 1334
                     S+ V G    + Q G      A T         P   S  +V       +P
Sbjct: 433  SSEKTTTVSSLVVNG----KPQVGTSESSEAYT---NPSFNGPAAHSGAKVTVEMNGATP 591

Query: 1335 EPEDPGVPFNTGARLILQ-----------HVQ---ALLVKRFHHTIRSRKDFVAQIVLPA 1380
                   PF +   + L            H+     + +K+  HT R+R     Q+ LP 
Sbjct: 592  SESSAVDPFASIENMALDSSYERLSDFALHMSRFWGMFMKKAIHTFRNRLISAVQLALPV 771

Query: 1381 TFVFLALMLSIIVPPFGEFPALTLHPWMY 1409
             F   AL +  ++P     P +TL   M+
Sbjct: 772  IFTIAALTVDKVLPKDFNGPPVTLDLGMF 858

 Score = 67.8 bits (164), Expect = 4e-11,   Method: Compositional matrix adjust.
 Identities = 48/163 (29%), Positives = 79/163 (48%), Gaps = 3/163 (1%)
 Frame = +1

Query: 2122 VVLTSHSMEECEALCTRLAIMVKGTFQCLGTIQHLKYKFGDGYIVTMKIKSPKDDLLPDL 2181
            ++L++H M+E + L  R+AIM +G  +C GT   LK  +G GY + M +K P+     D+
Sbjct: 13   LLLSTHFMDEADLLGDRIAIMAEGVVKCCGTSMFLKKLYGAGYHMVM-VKGPQ----CDV 177

Query: 2182 NPVEQFFQGNFPGSVQRERHHSMLQFQVP---SSSLARIFQLLISHKDSLLIEEYSVTQT 2238
              V    Q   PG+       + L F +P   +   A +F+++ S  D L I  +  T T
Sbjct: 178  ATVTAAVQAQLPGAQLESEIGAELSFLLPEEEAPKFADLFRVMESQSDELGITSFGATAT 357

Query: 2239 TLDQVFVNFAKQQTETYDLPLHPRAAGASWQAKLEEKSGRLQT 2281
            T+++VF+                 A+G S     EE +GR+Q+
Sbjct: 358  TMEEVFLKVG--------------ASGVS-----EEDNGRVQS 429
>27295
          Length = 384

 Score = 99.4 bits (246), Expect(2) = 2e-21,   Method: Compositional matrix adjust.
 Identities = 49/101 (48%), Positives = 64/101 (63%)
 Frame = +1

Query: 967  AGKTTTLSILTGLLPPTSGTVLIGGKDIETNLDVVRQSLGMCPQHNILFHHLTVAEHILF 1026
             GKTTT+S+LTG +PPTSGT  + G DI T+++ VR +LG+CPQHNILF  LTV EH+ F
Sbjct: 1    GGKTTTMSMLTGFIPPTSGTAFVNGYDIRTDINNVRSNLGLCPQHNILFDTLTVDEHLQF 180

Query: 1027 YAQLKGRSWXXXXXXXXXXXXDTGLHHKRNEEAQDLSGGMQ 1067
            +A+LKG               +  L  KR+  A  LSGG +
Sbjct: 181  FARLKGCPRDEIPGAVAEMAKEVDLESKRSALAGTLSGGTE 303

 Score = 23.5 bits (49), Expect(2) = 2e-21,   Method: Composition-based stats.
 Identities = 11/23 (47%), Positives = 17/23 (73%)
 Frame = +3

Query: 1071 SVAIAFVGDSKVVVLDEPTSGVD 1093
            S +++ V D ++  LDEPTSG+D
Sbjct: 318  SASLSLV-DPRL*YLDEPTSGMD 383

 Score = 77.8 bits (190), Expect(2) = 1e-15,   Method: Compositional matrix adjust.
 Identities = 45/101 (44%), Positives = 55/101 (54%)
 Frame = +1

Query: 1975 AGKTTTFKMLTGDTTVTSGDATVAGKSILTSISDVHQNMGYCPQFDAIDDLLTGREHLYL 2034
             GKTTT  MLTG    TSG A V G  I T I++V  N+G CPQ + + D LT  EHL  
Sbjct: 1    GGKTTTMSMLTGFIPPTSGTAFVNGYDIRTDINNVRSNLGLCPQHNILFDTLTVDEHLQF 180

Query: 2035 YARLRGVPSKEIEKVANWGIQSLGLSLYADRLAGTYSGGNK 2075
            +ARL+G P  EI        + + L      LAGT SGG +
Sbjct: 181  FARLKGCPRDEIPGAVAEMAKEVDLESKRSALAGTLSGGTE 303

 Score = 25.8 bits (55), Expect(2) = 1e-15,   Method: Composition-based stats.
 Identities = 11/15 (73%), Positives = 11/15 (73%)
 Frame = +2

Query: 2072 GGNKRKLSTAIALTG 2086
            GG KRKLS  IAL G
Sbjct: 293  GGQKRKLSVGIALIG 337
>01623
          Length = 1414

 Score = 74.3 bits (181), Expect = 5e-13,   Method: Compositional matrix adjust.
 Identities = 61/211 (28%), Positives = 101/211 (47%), Gaps = 12/211 (5%)
 Frame = +3

Query: 938  FEPSGRPAV---DRLNITFYENQITAFLGHNGAGKTTTLSILTGLLPPTSGTVLIGGKDI 994
            F   GRP V      N+     Q+TA +G +G+GK+T   +L     P +G V++ G++I
Sbjct: 48   FAYPGRPDVAIFKGFNLQARAGQVTAVVGPSGSGKSTVCGLLLRYYDPNAGQVMLDGQNI 227

Query: 995  -ETNLDVVRQSLGMCPQHNILFHHLTVAEHILFYAQ-----LKGRSWXXXXXXXXXXXXD 1048
             E +   +R  +G   Q  ILF   +VAE+I + A        G+               
Sbjct: 228  AELDPTWLRSHIGTVSQEPILFS-CSVAENIAYGAVNPDAVTLGQIEDAARKANAFNFVS 404

Query: 1049 T---GLHHKRNEEAQDLSGGMQRKLSVAIAFVGDSKVVVLDEPTSGVDPYSRRSIWDLLL 1105
            T   GL     E    LSGG ++++++A A + + ++++LDE TS +D  S   + D L 
Sbjct: 405  TFPLGLDTMVGERGMMLSGGQRQRIAIARAILKNPEILLLDEATSALDAESEYLVQDALE 584

Query: 1106 KYRSGRTIIMSTHHMDEADLLGDRIAIISQG 1136
            K   GRT+I   H +       ++IA+++ G
Sbjct: 585  KLMGGRTVITIAHRLSTIK-TANQIAVLTDG 674

 Score = 45.8 bits (107), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 25/100 (25%), Positives = 52/100 (52%)
 Frame = +3

Query: 2057 LGLSLYADRLAGTYSGGNKRKLSTAIALTGCPPLLLLDEPTTGMDPQARRMLWNTIVSII 2116
            LGL           SGG +++++ A A+   P +LLLDE T+ +D ++  ++ + +  ++
Sbjct: 414  LGLDTMVGERGMMLSGGQRQRIAIARAILKNPEILLLDEATSALDAESEYLVQDALEKLM 593

Query: 2117 REGRAVVLTSHSMEECEALCTRLAIMVKGTFQCLGTIQHL 2156
              GR V+  +H +   +    ++A++  G    +G+ Q L
Sbjct: 594  -GGRTVITIAHRLSTIKT-ANQIAVLTDGVVAEMGSYQDL 707
>26643
          Length = 440

 Score = 69.3 bits (168), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 29/75 (38%), Positives = 47/75 (62%), Gaps = 1/75 (1%)
 Frame = -1

Query: 370 CNSLIQSLESNPLTKIAWRAAKPLLMGKILFTPDSPAARRIMKNANSTFEELDRVRKLVK 429
           C ++  SL+ +  T+I WR  KP+++G I + PD+PA R+I+K AN TFE L  +  +  
Sbjct: 230 CKAIFNSLDGSAYTRILWRQIKPIVLGVIPYAPDTPAVRKIIKEANRTFESLGAIIGISD 51

Query: 430 AW-EEVGPQIWYFFE 443
            W  ++ PQ++ F E
Sbjct: 50  QWLNDISPQLYSFLE 6
>05764
          Length = 1395

 Score = 62.0 bits (149), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 44/179 (24%), Positives = 84/179 (46%), Gaps = 7/179 (3%)
 Frame = -2

Query: 949  LNITFYENQITAFLGHNGAGKTTTLSILTGLLPPTSGTVLIGGKDI-ETNLDVVRQSLGM 1007
            +++     Q  A +G +G GK+T +S+L     P+ G +L+ G D+ + N+  +R  L +
Sbjct: 1070 ISLEISAGQTAALVGISGCGKSTIISLLQRYYDPSKGRLLVDGTDVRDYNITALRSLLSV 891

Query: 1008 CPQHNILFHHLTVAEHILFYAQLKG------RSWXXXXXXXXXXXXDTGLHHKRNEEAQD 1061
              Q  ILF   ++ ++I +  +          +               G   +   +   
Sbjct: 890  VSQEPILFD-CSIRDNIQYGLESDVPMPDIIAACKTANIHEFIASLPQGYDTQVGGKGTQ 714

Query: 1062 LSGGMQRKLSVAIAFVGDSKVVVLDEPTSGVDPYSRRSIWDLLLKYRSGRTIIMSTHHM 1120
            LSGG ++++++A A V +  +++LDE TS +D  S + +   L   R GRT I+  H +
Sbjct: 713  LSGGQKQRVAIARALVRNPIILLLDEATSALDTESEKLVQAALDNAREGRTCIVIAHRL 537

 Score = 48.9 bits (115), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 42/189 (22%), Positives = 84/189 (44%), Gaps = 20/189 (10%)
 Frame = -2

Query: 1961 VRPGECFGLLGVNGAGKTTTFKMLTGDTTVTSGDATVAG-----------KSILTSIS-- 2007
            +  G+   L+G++G GK+T   +L      + G   V G           +S+L+ +S  
Sbjct: 1058 ISAGQTAALVGISGCGKSTIISLLQRYYDPSKGRLLVDGTDVRDYNITALRSLLSVVSQE 879

Query: 2008 ------DVHQNMGYCPQFDA-IDDLLTGREHLYLYARLRGVPSKEIEKVANWGIQSLGLS 2060
                   +  N+ Y  + D  + D++   +   ++  +  +P     +V   G Q     
Sbjct: 878  PILFDCSIRDNIQYGLESDVPMPDIIAACKTANIHEFIASLPQGYDTQVGGKGTQ----- 714

Query: 2061 LYADRLAGTYSGGNKRKLSTAIALTGCPPLLLLDEPTTGMDPQARRMLWNTIVSIIREGR 2120
                      SGG K++++ A AL   P +LLLDE T+ +D ++ +++   + +  REGR
Sbjct: 713  ---------LSGGQKQRVAIARALVRNPIILLLDEATSALDTESEKLVQAALDN-AREGR 564

Query: 2121 AVVLTSHSM 2129
              ++ +H +
Sbjct: 563  TCIVIAHRL 537
>20400
          Length = 409

 Score = 60.8 bits (146), Expect = 6e-09,   Method: Composition-based stats.
 Identities = 31/76 (40%), Positives = 48/76 (63%)
 Frame = -3

Query: 1205 VQELMDLVYHHVPEAKLVECIGQELIFLLPNKNFKQRAYASLFRELEETLADLGLSSFGI 1264
            V+ +   +  HVP A L     +EL ++LP +  K+  +  LF+ L+ +L DL ++S+G+
Sbjct: 254  VEAVSKFIQKHVPSAYLAADGQRELQYILPFEEAKKGNFRKLFQGLDASLPDLHINSYGV 75

Query: 1265 SDTPLEEIFLKVTEDA 1280
             DT LEEIFLK+TE A
Sbjct: 74   MDTNLEEIFLKITEAA 27

 Score = 30.4 bits (67), Expect = 9.8,   Method: Composition-based stats.
 Identities = 21/84 (25%), Positives = 36/84 (42%), Gaps = 6/84 (7%)
 Frame = -3

Query: 2172 SPKDDLLP-DLNPVEQFFQGNFPGSVQRERHHSMLQFQVP-----SSSLARIFQLLISHK 2225
            SPK    P  +  V +F Q + P +         LQ+ +P       +  ++FQ L +  
Sbjct: 284  SPKQACSPCSVEAVSKFIQKHVPSAYLAADGQRELQYILPFEEAKKGNFRKLFQGLDASL 105

Query: 2226 DSLLIEEYSVTQTTLDQVFVNFAK 2249
              L I  Y V  T L+++F+   +
Sbjct: 104  PDLHINSYGVMDTNLEEIFLKITE 33
>34140
          Length = 452

 Score = 60.5 bits (145), Expect = 9e-09,   Method: Compositional matrix adjust.
 Identities = 27/85 (31%), Positives = 44/85 (51%), Gaps = 1/85 (1%)
 Frame = +3

Query: 370 CNSLIQSLESNPLTKIAWRAAKPLLMGKILFTPDSPAARRIMKNANSTFEELDRVRKLVK 429
           C  +  +L  + +T   W+  +P+++G I + PD+PA R+I+K AN TFE L  V  L  
Sbjct: 141 CEMIFSALNQSSMTSALWKQIQPIVLGNISYAPDTPAVRKIIKQANRTFESLGSVMDLAD 320

Query: 430 AW-EEVGPQIWYFFEKSTQMTVIRD 453
            W   + P    F E    +  +R+
Sbjct: 321 QWLTTLSPDFNSFLESGPAVQFLRN 395
>02301
          Length = 1098

 Score = 57.0 bits (136), Expect = 8e-08,   Method: Compositional matrix adjust.
 Identities = 47/200 (23%), Positives = 90/200 (45%), Gaps = 6/200 (3%)
 Frame = -2

Query: 969  KTTTLSILTGLLPPTSGTVLIGGKDI-ETNLDVVRQSLGMCPQHNILFHHLTVAEHILFY 1027
            K+T +S+L     P+SG VL+ G  + +     +   + +  Q  +LF   ++ ++I + 
Sbjct: 980  KSTCVSLLQNFYQPSSGLVLLDGVPVHQYQHHCLHSKMALVGQEPVLFSR-SIKDNIGYG 804

Query: 1028 AQLKGRSWXXXXXXXXXX-----XXDTGLHHKRNEEAQDLSGGMQRKLSVAIAFVGDSKV 1082
             +    S                    G      E    LSGG +++L++A A V    +
Sbjct: 803  PEQYNDSDIVTAAMKANAHDFIRALPRGYDTSVGERGLLLSGGQKQRLAIARALVRQPAI 624

Query: 1083 VVLDEPTSGVDPYSRRSIWDLLLKYRSGRTIIMSTHHMDEADLLGDRIAIISQGRLYCSG 1142
            ++LDE TS +D  S   +   + +   GRT+++  H +   +   DR+ +I++GR+   G
Sbjct: 623  LLLDEATSALDTQSESLVQSAINECTRGRTVVIIAHRLTTVE-KADRVLVINKGRVVEEG 447

Query: 1143 TPLFLKNCFGTGFYLTLVRK 1162
            +P  L      G + +L R+
Sbjct: 446  SPSHLLKL--GGMFTSLARQ 393

 Score = 56.2 bits (134), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 54/198 (27%), Positives = 89/198 (44%), Gaps = 5/198 (2%)
 Frame = -2

Query: 1995 ATVAGKSILTSISDVHQNMGYCPQFDAIDDLLTGREHLYLYARLRGVPSKEIEKVANWGI 2054
            A V  + +L S S +  N+GY P+     D++T       +  +R +P      V   G+
Sbjct: 866  ALVGQEPVLFSRS-IKDNIGYGPEQYNDSDIVTAAMKANAHDFIRALPRGYDTSVGERGL 690

Query: 2055 QSLGLSLYADRLAGTYSGGNKRKLSTAIALTGCPPLLLLDEPTTGMDPQARRMLWNTIVS 2114
                            SGG K++L+ A AL   P +LLLDE T+ +D Q+  ++ + I  
Sbjct: 689  --------------LLSGGQKQRLAIARALVRQPAILLLDEATSALDTQSESLVQSAINE 552

Query: 2115 IIREGRAVVLTSHSMEECEALCTRLAIMVKGTFQCLGTIQHLKYKFGDGYIVTMK---IK 2171
              R GR VV+ +H +   E    R+ ++ KG     G+  HL  K G  +    +   I 
Sbjct: 551  CTR-GRTVVIIAHRLTTVEK-ADRVLVINKGRVVEEGSPSHL-LKLGGMFTSLARQQLIG 381

Query: 2172 SPKDDLLP--DLNPVEQF 2187
            + K+ L P   +NP ++ 
Sbjct: 380  TXKNSLSPLYYINPADEV 327
>22529
          Length = 312

 Score = 43.5 bits (101), Expect = 0.001,   Method: Composition-based stats.
 Identities = 29/90 (32%), Positives = 44/90 (48%)
 Frame = +3

Query: 1076 FVGDSKVVVLDEPTSGVDPYSRRSIWDLLLKYRSGRTIIMSTHHMDEADLLGDRIAIISQ 1135
             V + K+++LDE TS +D  S +++ D L K R GRT I+  H +       D I    +
Sbjct: 3    LVRNPKILLLDEATSALDMESEKTVQDALDKARQGRTTIVIAHRLSTIK-TADIIISFKE 179

Query: 1136 GRLYCSGTPLFLKNCFGTGFYLTLVRKMKN 1165
            G+++  GT   L +    G Y  LV    N
Sbjct: 180  GKVFEQGTHADLMS--KQGIYYQLVMNQTN 263
>30281
          Length = 821

 Score = 42.7 bits (99), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 27/91 (29%), Positives = 51/91 (56%), Gaps = 3/91 (3%)
 Frame = -2

Query: 1056 NEEAQDLSGGMQRKLSVAIAFVGDSKVVVLDEPTSGVDPYSRRSIWDLLLKYRS---GRT 1112
             E+  +LSGG ++++SVA A   DS V +LD+P S VD +  ++I+  ++       G T
Sbjct: 652  GEKGINLSGGQKQRVSVARAVYSDSDVYLLDDPLSAVDSHVGKAIFSKVIGPNGLLRGTT 473

Query: 1113 IIMSTHHMDEADLLGDRIAIISQGRLYCSGT 1143
             ++ TH +    ++ D I ++  G++   G+
Sbjct: 472  RVLVTHGVHWLPMV-DEILVLMDGKISERGS 383

 Score = 32.7 bits (73), Expect = 1.8,   Method: Compositional matrix adjust.
 Identities = 20/89 (22%), Positives = 45/89 (50%), Gaps = 3/89 (3%)
 Frame = -2

Query: 2071 SGGNKRKLSTAIALTGCPPLLLLDEPTTGMDPQARRMLWNTIV---SIIREGRAVVLTSH 2127
            SGG K+++S A A+     + LLD+P + +D    + +++ ++    ++R G   VL +H
Sbjct: 631  SGGQKQRVSVARAVYSDSDVYLLDDPLSAVDSHVGKAIFSKVIGPNGLLR-GTTRVLVTH 455

Query: 2128 SMEECEALCTRLAIMVKGTFQCLGTIQHL 2156
             +     +   + +++ G     G+ + L
Sbjct: 454  GVHWL-PMVDEILVLMDGKISERGSYEEL 371
>20290
          Length = 1550

 Score = 36.6 bits (83), Expect = 0.14,   Method: Compositional matrix adjust.
 Identities = 20/81 (24%), Positives = 43/81 (53%), Gaps = 2/81 (2%)
 Frame = +3

Query: 1056 NEEAQDLSGGMQRKLSVAIAFVGDSKVVVLDEPTSGVDPYSRRSIWDLLLKY--RSGRTI 1113
            ++E Q+LSGG  +++++ +     + V ++DEP++ +D   R     ++ +Y   + +T 
Sbjct: 1029 DQEVQNLSGGELQRVALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRYILHAKKTG 1208

Query: 1114 IMSTHHMDEADLLGDRIAIIS 1134
             +  H    A  L DR+ +I 
Sbjct: 1209 FVVEHDFIMATYLADRVIVIE 1271
>03538
          Length = 1974

 Score = 36.6 bits (83), Expect = 0.14,   Method: Compositional matrix adjust.
 Identities = 40/154 (25%), Positives = 66/154 (42%), Gaps = 1/154 (0%)
 Frame = -1

Query: 966  GAGKTTTLSILTGLLPPTSGTVLIGGKDIETNLDVVRQSLGMCPQHNILFHHLTVAEHIL 1025
            G GK+T L +L G L P+ G   +            R  +G   QH+     L + E  +
Sbjct: 1971 GVGKSTLLKLLMGDLQPSQGEKRMNH----------RLRVGKYDQHSA--DQLNLDESPV 1828

Query: 1026 FYAQLKGRSWXXXXXXXXXXXXDTGL-HHKRNEEAQDLSGGMQRKLSVAIAFVGDSKVVV 1084
             Y +   R +              GL  H      +DLSGG + ++++A        V+V
Sbjct: 1827 EYLK---RLFDLQYQDARKMLGRVGLASHAHTILNRDLSGGQRARVALAELSCRAPDVLV 1657

Query: 1085 LDEPTSGVDPYSRRSIWDLLLKYRSGRTIIMSTH 1118
            LDEPT+ +D  S  ++ D +  +  G  +I+ +H
Sbjct: 1656 LDEPTNNLDIESIDALADAIKNFTGG--VIIVSH 1561

 Score = 33.5 bits (75), Expect = 1.0,   Method: Compositional matrix adjust.
 Identities = 38/156 (24%), Positives = 67/156 (42%), Gaps = 1/156 (0%)
 Frame = -1

Query: 1974 GAGKTTTFKMLTGDTTVTSGDATVAGKSILTSISDVHQNMGYCPQFDAIDDLLTGREHLY 2033
            G GK+T  K+L GD   + G+  +  +            +G   Q  A D L      + 
Sbjct: 1971 GVGKSTLLKLLMGDLQPSQGEKRMNHRL----------RVGKYDQHSA-DQLNLDESPVE 1825

Query: 2034 LYARLRGVPSKEIEKVANWGIQSLGLSLYADR-LAGTYSGGNKRKLSTAIALTGCPPLLL 2092
               RL  +  ++  K+    +  +GL+ +A   L    SGG + +++ A      P +L+
Sbjct: 1824 YLKRLFDLQYQDARKM----LGRVGLASHAHTILNRDLSGGQRARVALAELSCRAPDVLV 1657

Query: 2093 LDEPTTGMDPQARRMLWNTIVSIIREGRAVVLTSHS 2128
            LDEPT  +D ++   L + I +       V++ SH 
Sbjct: 1656 LDEPTNNLDIESIDALADAIKNFT---GGVIIVSHD 1558
>22801
          Length = 753

 Score = 33.9 bits (76), Expect = 0.71,   Method: Composition-based stats.
 Identities = 18/55 (32%), Positives = 32/55 (58%)
 Frame = -1

Query: 1060 QDLSGGMQRKLSVAIAFVGDSKVVVLDEPTSGVDPYSRRSIWDLLLKYRSGRTII 1114
            +DLSGG + ++++A        V+VLDEPT+ +D  S  ++ D +  +  G  I+
Sbjct: 738  RDLSGGQRARVALAELSCRAPDVLVLDEPTNNLDIESIDALADAIKNFTGGVIIV 574
>33849
          Length = 266

 Score = 32.7 bits (73), Expect = 1.7,   Method: Composition-based stats.
 Identities = 13/27 (48%), Positives = 19/27 (70%)
 Frame = +1

Query: 42 LRNANPLYSQHECHFPNKAMPSAGLLP 68
          LR+ +PL+ QHE H  ++A P  G+LP
Sbjct: 25 LRSPHPLFLQHELHHAHRAAPLRGVLP 105
>18248
          Length = 466

 Score = 32.3 bits (72), Expect = 2.4,   Method: Compositional matrix adjust.
 Identities = 39/131 (29%), Positives = 51/131 (38%), Gaps = 23/131 (17%)
 Frame = +3

Query: 1961 VRPGE-----CFGLLGVNGAGKTTTFKMLTGDTTVTSGDAT----VAGKSILTSISDVHQ 2011
            V PGE        +LG NG GKTT  KML G      G  T    V+ K     IS  HQ
Sbjct: 75   VHPGEFTDSEIIVMLGENGTGKTTFIKMLAGKLEPDEGGPTPVLNVSYKP--QKISPKHQ 248

Query: 2012 NM-----------GYC-PQF--DAIDDLLTGREHLYLYARLRGVPSKEIEKVANWGIQSL 2057
                          Y  PQF  D +  L    EH++          +E++K+  W   + 
Sbjct: 249  GTVRQLLHERIRDAYIHPQFVTDVVKPLQI--EHIF---------DQEVQKLVRW*AATC 395

Query: 2058 GLSLYADRLAG 2068
            GL L   + +G
Sbjct: 396  GLDLVPGKTSG 428
>38795
          Length = 792

 Score = 30.4 bits (67), Expect = 9.0,   Method: Compositional matrix adjust.
 Identities = 36/121 (29%), Positives = 54/121 (44%), Gaps = 1/121 (0%)
 Frame = +1

Query: 2032 LYLYARLRGVPSKEIEKVANWGIQSLGLSLYADRL-AGTYSGGNKRKLSTAIALTGCPPL 2090
            L +Y RL  + S +    A + +  LG S          +SGG + ++  A AL   P L
Sbjct: 16   LAVYDRLDELDSTKALAKAGFILHGLGFSKDMQHTKVKNFSGGWRMRIGLARALYLRPSL 195

Query: 2091 LLLDEPTTGMDPQARRMLWNTIVSIIREGRAVVLTSHSMEECEALCTRLAIMVKGTFQCL 2150
            LLLDEPT  +D  A   L   + +     R +V+ SHS +    +C  +  M +   Q  
Sbjct: 196  LLLDEPTNHLDLNACVWLEEELKNY---PRILVIISHSQDFLNGVCNSIIHMNQKKLQYY 366

Query: 2151 G 2151
            G
Sbjct: 367  G 369
>06007
          Length = 516

 Score = 30.4 bits (67), Expect = 9.2,   Method: Composition-based stats.
 Identities = 20/72 (27%), Positives = 30/72 (41%), Gaps = 1/72 (1%)
 Frame = -2

Query: 2185 EQFFQGNFPGSVQRE-RHHSMLQFQVPSSSLARIFQLLISHKDSLLIEEYSVTQTTLDQV 2243
            +QF+   F G  +    HH  L   V S  +  I   +ISH       + SV   TL Q 
Sbjct: 422  QQFYLSTFSGVNEHSWNHHDALTRHVGSEQVNHINLNVISHHIETKPHQKSVKSLTLSQA 243

Query: 2244 FVNFAKQQTETY 2255
            ++   K+  + Y
Sbjct: 242  YITTNKKSLQFY 207
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|13386276|ref|NP_082279.1| RNA polymerase II
associated protein 3 [Mus musculus]
         (660 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

35341                                                                 105   5e-23
35264                                                                  76   5e-14
35348                                                                  72   5e-13
01124                                                                  67   2e-11
30337                                                                  65   1e-10
00888                                                                  63   3e-10
08670                                                                  62   1e-09
04645                                                                  58   1e-08
23484                                                                  52   1e-06
22027                                                                  46   5e-05
13560                                                                  37   0.037
13998                                                                  35   0.12 
11978                                                                  34   0.24 
17595                                                                  32   0.77 
19619                                                                  30   3.3  
18089                                                                  28   9.4  
>35341
          Length = 641

 Score =  105 bits (262), Expect = 5e-23,   Method: Compositional matrix adjust.
 Identities = 63/133 (47%), Positives = 83/133 (62%), Gaps = 4/133 (3%)
 Frame = +3

Query: 314 DRTNALLPANRAMAYLKIQRYEEAERDCTQAIVLDGSYSKAFARRGTARTFLGKINEAKQ 373
           D TNALLPANRAMA +K+++Y  AE DCT AI LD  Y KA+ RR  AR  + ++  A +
Sbjct: 12  DPTNALLPANRAMALIKMEKYGVAEVDCTTAITLDPLYVKAYLRRAAARVGMQRLQPALE 191

Query: 374 DFETVLLLEPGNKQAATELSRIKKEL---IEKGHWDDVFLDSTQRHHVVKAVDNPP-RGS 429
           D+E VL LEP +KQA  E+ R++KEL    E        L++ Q    VKAV  PP + S
Sbjct: 192 DYERVLQLEPNSKQAQKEVDRLRKELDREKEDARPTSTSLETMQTSE-VKAVYKPPEQRS 368

Query: 430 PKALKKVFIEETG 442
            K L+++ IEE G
Sbjct: 369 KKPLRRIEIEEIG 407

 Score = 94.0 bits (232), Expect = 2e-19,   Method: Compositional matrix adjust.
 Identities = 43/89 (48%), Positives = 61/89 (68%)
 Frame = +3

Query: 161 MDADPYNPVLPTNRASAYFRLKKFAVAESDCNLAIALSRTYTKAYARRGAARFALQKLED 220
           MD DP N +LP NRA A  +++K+ VAE DC  AI L   Y KAY RR AAR  +Q+L+ 
Sbjct: 3   MDLDPTNALLPANRAMALIKMEKYGVAEVDCTTAITLDPLYVKAYLRRAAARVGMQRLQP 182

Query: 221 ARKDYEKVLELEPDNFEATNELRKINQAL 249
           A +DYE+VL+LEP++ +A  E+ ++ + L
Sbjct: 183 ALEDYERVLQLEPNSKQAQKEVDRLRKEL 269
>35264
          Length = 867

 Score = 75.9 bits (185), Expect = 5e-14,   Method: Compositional matrix adjust.
 Identities = 65/235 (27%), Positives = 100/235 (42%), Gaps = 24/235 (10%)
 Frame = +3

Query: 278 QQGRQKAIAEKDLGNGFFKEGKYEQAIECYTRGIAADRTNALLPANRAMAYLKIQRYEEA 337
           Q+GR++ +          +  KY++A+ECYT  I    + A    NRA  Y+ +++Y E 
Sbjct: 48  QEGRRQRV---------LQAAKYKEALECYTCAINLCPSCAAYYGNRAATYMMLKKYREG 200

Query: 338 ERDCTQAIVLDGSYSKAFARRGTARTFLGKINEAKQDFETVLLLEPGNKQAATELSRIKK 397
            +D  QA+ LD ++ K + R G     LG    A  +F  VL L+ GN  A TEL R+K 
Sbjct: 201 LKDAQQAVQLDPTFVKGYIREGKCHLMLGNSMAASSNFNRVLELDAGNSTAVTELKRVKT 380

Query: 398 ----------ELIEKGHWDDVF-LDSTQRHH-------VVKA------VDNPPRGSPKAL 433
                       +   H   ++ LD    H        V+KA      VD   R  P+ L
Sbjct: 381 LQELETKVDLNFVRGEHRTALYCLDRCLEHSPASLRFKVLKAEALSFWVD---RQRPRNL 551

Query: 434 KKVFIEETGNLIETVDAPDSSATVPESDRATAAVGTGTKKNPSEGVSLPAGDRPR 488
           +  F  +TG +       D + T+             T++ PS   S+P  D P+
Sbjct: 552 QMTFYRKTG*MRTLCT*GD*ACTIRT-----------TQRKPSSIFSMPC-DWPQ 680

 Score = 64.3 bits (155), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 34/103 (33%), Positives = 50/103 (48%)
 Frame = +3

Query: 143 KYFKQGKYDEAIECYTKGMDADPYNPVLPTNRASAYFRLKKFAVAESDCNLAIALSRTYT 202
           +  +  KY EA+ECYT  ++  P       NRA+ Y  LKK+     D   A+ L  T+ 
Sbjct: 66  RVLQAAKYKEALECYTCAINLCPSCAAYYGNRAATYMMLKKYREGLKDAQQAVQLDPTFV 245

Query: 203 KAYARRGAARFALQKLEDARKDYEKVLELEPDNFEATNELRKI 245
           K Y R G     L     A  ++ +VLEL+  N  A  EL+++
Sbjct: 246 KGYIREGKCHLMLGNSMAASSNFNRVLELDAGNSTAVTELKRV 374
>35348
          Length = 627

 Score = 72.4 bits (176), Expect = 5e-13,   Method: Compositional matrix adjust.
 Identities = 44/119 (36%), Positives = 69/119 (57%), Gaps = 8/119 (6%)
 Frame = -2

Query: 134 ALVLKEKGNKYFKQGKYDEAIECYTKGMDADPYN-----PVLPTNRASAYFRLKKFAVAE 188
           A+ +K +GN  FK G+Y EA+E Y++G+D  P        V+ +NRA+   + + +  A 
Sbjct: 584 AVKVKVRGNDTFKSGQYAEALELYSEGLDICPLKYVQQRSVMLSNRAACRIKKEDYQKAV 405

Query: 189 SDCNLAIALSRTYTKAYARRGAARFALQKLEDARKDYEKVLEL---EPDNFEATNELRK 244
            DC  +I L+  Y KAY RR  A   L+KL+DA KD+ +V+E+   + D+ +A   L K
Sbjct: 404 GDCTKSIDLNPAYIKAYFRRADAYEKLEKLDDALKDHRQVVEMDRSQIDSIQACLRLEK 228

 Score = 60.5 bits (145), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 38/124 (30%), Positives = 70/124 (56%), Gaps = 5/124 (4%)
 Frame = -2

Query: 284 AIAEKDLGNGFFKEGKYEQAIECYTRGIAAD-----RTNALLPANRAMAYLKIQRYEEAE 338
           A+  K  GN  FK G+Y +A+E Y+ G+        +  +++ +NRA   +K + Y++A 
Sbjct: 584 AVKVKVRGNDTFKSGQYAEALELYSEGLDICPLKYVQQRSVMLSNRAACRIKKEDYQKAV 405

Query: 339 RDCTQAIVLDGSYSKAFARRGTARTFLGKINEAKQDFETVLLLEPGNKQAATELSRIKKE 398
            DCT++I L+ +Y KA+ RR  A   L K+++A +D   V+ ++     +     R++KE
Sbjct: 404 GDCTKSIDLNPAYIKAYFRRADAYEKLEKLDDALKDHRQVVEMDRSQIDSIQACLRLEKE 225

Query: 399 LIEK 402
           + E+
Sbjct: 224 IEER 213
>01124
          Length = 1372

 Score = 67.0 bits (162), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 37/121 (30%), Positives = 62/121 (51%), Gaps = 8/121 (6%)
 Frame = -3

Query: 137 LKEKGNKYFKQGKYDEAIECYTKGMDADPYNPVLPTNRASAYFRLKKFAVAESDCNLAIA 196
           L++KGN +F  G Y  A+  YT  +  +P  P L +NRA+ + +L+       DC+ A+ 
Sbjct: 746 LRDKGNGFFASGNYQAAVNVYTHALRLNPKMPSLYSNRAACHLKLRNLFKCIEDCSKAMD 567

Query: 197 L--------SRTYTKAYARRGAARFALQKLEDARKDYEKVLELEPDNFEATNELRKINQA 248
           L        + +  KA  RRG A   L+   +  +DYE  L+L+P+N +   +  K+ Q 
Sbjct: 566 LLSPPVPQNAASRVKAMVRRGTAFCQLEMYVEGLQDYEAALKLDPNNQQLKEDAEKMRQI 387

Query: 249 L 249
           +
Sbjct: 386 I 384

 Score = 65.5 bits (158), Expect = 7e-11,   Method: Compositional matrix adjust.
 Identities = 41/111 (36%), Positives = 57/111 (51%), Gaps = 11/111 (9%)
 Frame = -3

Query: 288 KDLGNGFFKEGKYEQAIECYTRGIAADRTNALLP---ANRAMAYLKIQRYEEAERDCTQA 344
           +D GNGFF  G Y+ A+  YT  +   R N  +P   +NRA  +LK++   +   DC++A
Sbjct: 743 RDKGNGFFASGNYQAAVNVYTHAL---RLNPKMPSLYSNRAACHLKLRNLFKCIEDCSKA 573

Query: 345 IVL--------DGSYSKAFARRGTARTFLGKINEAKQDFETVLLLEPGNKQ 387
           + L          S  KA  RRGTA   L    E  QD+E  L L+P N+Q
Sbjct: 572 MDLLSPPVPQNAASRVKAMVRRGTAFCQLEMYVEGLQDYEAALKLDPNNQQ 420
>30337
          Length = 493

 Score = 64.7 bits (156), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 36/101 (35%), Positives = 51/101 (50%)
 Frame = -1

Query: 134 ALVLKEKGNKYFKQGKYDEAIECYTKGMDADPYNPVLPTNRASAYFRLKKFAVAESDCNL 193
           A+ LK +GNK F   KY++AI CYTK +  +P      TNRA  Y +L+ + +A  DC  
Sbjct: 331 AIDLKNQGNKLFAARKYEDAIHCYTKAIMKNPNTATYFTNRALCYIKLRNWELASQDCQR 152

Query: 194 AIALSRTYTKAYARRGAARFALQKLEDARKDYEKVLELEPD 234
           A+ L R   K +   G A   L   ++A     K  +L  D
Sbjct: 151 ALELDRNLVKGHFFLGQALVELAMYDEAITHLMKAHDLAKD 29

 Score = 62.8 bits (151), Expect = 4e-10,   Method: Compositional matrix adjust.
 Identities = 35/93 (37%), Positives = 49/93 (52%)
 Frame = -1

Query: 279 QGRQKAIAEKDLGNGFFKEGKYEQAIECYTRGIAADRTNALLPANRAMAYLKIQRYEEAE 338
           Q +  AI  K+ GN  F   KYE AI CYT+ I  +   A    NRA+ Y+K++ +E A 
Sbjct: 346 QRKMSAIDLKNQGNKLFAARKYEDAIHCYTKAIMKNPNTATYFTNRALCYIKLRNWELAS 167

Query: 339 RDCTQAIVLDGSYSKAFARRGTARTFLGKINEA 371
           +DC +A+ LD +  K     G A   L   +EA
Sbjct: 166 QDCQRALELDRNLVKGHFFLGQALVELAMYDEA 68
>00888
          Length = 970

 Score = 63.2 bits (152), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 43/124 (34%), Positives = 61/124 (49%), Gaps = 16/124 (12%)
 Frame = -3

Query: 281 RQKAIAEKDLGNGFFKEGKYEQAIECYTRGIA--------------ADRTNALLPA--NR 324
           + K I EK  G   FK+GKY++A+  Y + ++              +D+   ++ A  N 
Sbjct: 743 QSKIIKEK--GTAAFKKGKYQRALTNYEKIVSFLEHESTGLSDSELSDKHQLMVAAFLNI 570

Query: 325 AMAYLKIQRYEEAERDCTQAIVLDGSYSKAFARRGTARTFLGKINEAKQDFETVLLLEPG 384
           AM  LK+  Y +AE  C + + +  +  KA  RRG AR       EA  DF  VL LEPG
Sbjct: 569 AMCQLKLLDYRQAEETCNKVLAMSTNNVKALFRRGQARLECADYTEAASDFSKVLELEPG 390

Query: 385 NKQA 388
           NK A
Sbjct: 389 NKAA 378

 Score = 60.8 bits (146), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 42/122 (34%), Positives = 58/122 (47%), Gaps = 16/122 (13%)
 Frame = -3

Query: 136 VLKEKGNKYFKQGKYDEAIECYTK----------GMD----ADPYNPVLPT--NRASAYF 179
           ++KEKG   FK+GKY  A+  Y K          G+     +D +  ++    N A    
Sbjct: 734 IIKEKGTAAFKKGKYQRALTNYEKIVSFLEHESTGLSDSELSDKHQLMVAAFLNIAMCQL 555

Query: 180 RLKKFAVAESDCNLAIALSRTYTKAYARRGAARFALQKLEDARKDYEKVLELEPDNFEAT 239
           +L  +  AE  CN  +A+S    KA  RRG AR       +A  D+ KVLELEP N  A 
Sbjct: 554 KLLDYRQAEETCNKVLAMSTNNVKALFRRGQARLECADYTEAASDFSKVLELEPGNKAAK 375

Query: 240 NE 241
           N+
Sbjct: 374 NQ 369
>08670
          Length = 1307

 Score = 61.6 bits (148), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 41/141 (29%), Positives = 71/141 (50%), Gaps = 1/141 (0%)
 Frame = +3

Query: 291 GNGFFKEGKYEQAIECYTRGIAADRTNALLPANRAMAYLKIQRYEEAERDCTQAIVLDGS 350
           GN   +  +Y  AI+ +T  IA D  +     NR+  Y ++Q+YE+A +D  +AI L   
Sbjct: 393 GNEMAQVEEYSAAIQLFTEAIALDPKDFRFLGNRSYCYDRLQQYEKALKDAEKAIKLSKD 572

Query: 351 YSKAFARRGTARTFLGKINEAKQDFETVLLLEPGNKQAATELSRIK-KELIEKGHWDDVF 409
           + K + R+G A   L K +EA++ F  VL L+   ++A  EL +++ ++L + G      
Sbjct: 573 WPKGYFRKGRALAGLCKFSEAEESFLQVLKLDKNCEEAVQELQQVRTRQLTDMGF----- 737

Query: 410 LDSTQRHHVVKAVDNPPRGSP 430
                    + A+ N P+  P
Sbjct: 738 ----SHGQALAAIKNTPQCPP 788
>04645
          Length = 1075

 Score = 58.2 bits (139), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 31/86 (36%), Positives = 48/86 (55%)
 Frame = +3

Query: 297 EGKYEQAIECYTRGIAADRTNALLPANRAMAYLKIQRYEEAERDCTQAIVLDGSYSKAFA 356
           EG+ E AI  +T  I ++ T+ALL A R  AYLK+ + ++A  DC++AI L+   ++ + 
Sbjct: 483 EGRLEDAIGFFTDAIKSNPTSALLYAKRGSAYLKMGKPKKAIHDCSKAIELNPDSAQGYK 662

Query: 357 RRGTARTFLGKINEAKQDFETVLLLE 382
            RG A   LG   E+  D      L+
Sbjct: 663 WRGKAHKLLGHWEESYHDLTLACKLD 740

 Score = 45.4 bits (106), Expect = 7e-05,   Method: Compositional matrix adjust.
 Identities = 26/89 (29%), Positives = 46/89 (51%)
 Frame = +3

Query: 147 QGKYDEAIECYTKGMDADPYNPVLPTNRASAYFRLKKFAVAESDCNLAIALSRTYTKAYA 206
           +G+ ++AI  +T  + ++P + +L   R SAY ++ K   A  DC+ AI L+    + Y 
Sbjct: 483 EGRLEDAIGFFTDAIKSNPTSALLYAKRGSAYLKMGKPKKAIHDCSKAIELNPDSAQGYK 662

Query: 207 RRGAARFALQKLEDARKDYEKVLELEPDN 235
            RG A   L   E++  D     +L+ D+
Sbjct: 663 WRGKAHKLLGHWEESYHDLTLACKLDYDD 749

 Score = 37.7 bits (86), Expect = 0.015,   Method: Compositional matrix adjust.
 Identities = 27/91 (29%), Positives = 44/91 (48%)
 Frame = +3

Query: 323 NRAMAYLKIQRYEEAERDCTQAIVLDGSYSKAFARRGTARTFLGKINEAKQDFETVLLLE 382
           N+AM  +   R E+A    T AI  + + +  +A+RG+A   +GK  +A  D    + L 
Sbjct: 459 NQAMDAMAEGRLEDAIGFFTDAIKSNPTSALLYAKRGSAYLKMGKPKKAIHDCSKAIELN 638

Query: 383 PGNKQAATELSRIKKELIEKGHWDDVFLDST 413
           P + Q      +  K L   GHW++ + D T
Sbjct: 639 PDSAQGYKWRGKAHKLL---GHWEESYHDLT 722
>23484
          Length = 1647

 Score = 51.6 bits (122), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 31/100 (31%), Positives = 47/100 (47%), Gaps = 4/100 (4%)
 Frame = +1

Query: 291 GNGFFKEGKYEQAIECYTRGIAADR----TNALLPANRAMAYLKIQRYEEAERDCTQAIV 346
           GN  FK+  Y  A++ Y  GI ++      NA+L  NRA A+  +  Y  A  DC  A  
Sbjct: 520 GNDLFKKKDYRLAVDNYXEGIKSNSPQRLQNAVLYTNRAAAHFHLGNYRSAFNDCFAARK 699

Query: 347 LDGSYSKAFARRGTARTFLGKINEAKQDFETVLLLEPGNK 386
               + KA  R       + K N+  +  +  L++EPG+K
Sbjct: 700 FKPDHLKALVRGAMCCDKMNKHNDTLRWCDAGLMVEPGHK 819

 Score = 46.6 bits (109), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 33/112 (29%), Positives = 55/112 (49%), Gaps = 4/112 (3%)
 Frame = +1

Query: 133 KALVLKEKGNKYFKQGKYDEAIECYTKGMDADP----YNPVLPTNRASAYFRLKKFAVAE 188
           +A   +E+GN  FK+  Y  A++ Y +G+ ++      N VL TNRA+A+F L  +  A 
Sbjct: 496 RAESYREEGNDLFKKKDYRLAVDNYXEGIKSNSPQRLQNAVLYTNRAAAHFHLGNYRSAF 675

Query: 189 SDCNLAIALSRTYTKAYARRGAARFALQKLEDARKDYEKVLELEPDNFEATN 240
           +DC  A      + KA  R       + K  D  +  +  L +EP + + T+
Sbjct: 676 NDCFAARKFKPDHLKALVRGAMCCDKMNKHNDTLRWCDAGLMVEPGHKDLTD 831
>22027
          Length = 692

 Score = 45.8 bits (107), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 22/69 (31%), Positives = 38/69 (55%), Gaps = 10/69 (14%)
 Frame = -3

Query: 132 QKALVLKEKGNKYFKQGKYDEAIECYTKGMDADPYN----------PVLPTNRASAYFRL 181
           ++A  L+  GN++FK GKYD+A+ CY   +   P++           +   NR++A+F L
Sbjct: 282 EQAEALRTTGNEHFKCGKYDKALSCYNNAVRYAPHSTLDINSCNVLALCFGNRSAAFFHL 103

Query: 182 KKFAVAESD 190
           K+F    +D
Sbjct: 102 KQFHSCLAD 76

 Score = 37.0 bits (84), Expect = 0.027,   Method: Compositional matrix adjust.
 Identities = 24/84 (28%), Positives = 40/84 (47%), Gaps = 12/84 (14%)
 Frame = -3

Query: 274 PTGGQQGR--QKAIAEKDLGNGFFKEGKYEQAIECY----------TRGIAADRTNALLP 321
           P   +QG+  ++A A +  GN  FK GKY++A+ CY          T  I +    AL  
Sbjct: 312 PELSRQGKSVEQAEALRTTGNEHFKCGKYDKALSCYNNAVRYAPHSTLDINSCNVLALCF 133

Query: 322 ANRAMAYLKIQRYEEAERDCTQAI 345
            NR+ A+  ++++     D   A+
Sbjct: 132 GNRSAAFFHLKQFHSCLADIDNAL 61
>13560
          Length = 978

 Score = 36.6 bits (83), Expect = 0.037,   Method: Compositional matrix adjust.
 Identities = 36/135 (26%), Positives = 53/135 (39%), Gaps = 19/135 (14%)
 Frame = +1

Query: 134 ALVLKEKGNKYFKQGKYDEAIECYTKG----MDADPY----NPVLPTNR----ASAYFRL 181
           A V KEKG +YFK G    A   +       +   PY    + V  T+        Y  L
Sbjct: 190 ASVHKEKGAQYFKTGNIFAAFSHFRTAIRLLLSVLPYSFSDDEVASTSHLQLLCQCYLNL 369

Query: 182 KKFAVAE-------SDCNLAIALSRTYTKAYARRGAARFALQKLEDARKDYEKVLELEPD 234
               +         ++C  A+ L     KA  RR +A   L  L  A +D E  L+ EP+
Sbjct: 370 AACQIKSGHHKHVITNCTHALNLDPANVKALYRRASANVNLGNLLHAHEDLETGLQKEPN 549

Query: 235 NFEATNELRKINQAL 249
           N    + ++ +N  L
Sbjct: 550 NRALLDLMQNVNARL 594
>13998
          Length = 1075

 Score = 34.7 bits (78), Expect = 0.12,   Method: Compositional matrix adjust.
 Identities = 19/46 (41%), Positives = 25/46 (54%)
 Frame = +1

Query: 187 AESDCNLAIALSRTYTKAYARRGAARFALQKLEDARKDYEKVLELE 232
           A +DCN  + L+  Y KA   R      L+K E+A  DYE  L+LE
Sbjct: 1   AVADCNRVLDLNSQYLKALLLRARCNNDLEKFEEAVADYETALQLE 138

 Score = 32.7 bits (73), Expect = 0.43,   Method: Compositional matrix adjust.
 Identities = 17/43 (39%), Positives = 21/43 (48%)
 Frame = +1

Query: 340 DCTQAIVLDGSYSKAFARRGTARTFLGKINEAKQDFETVLLLE 382
           DC + + L+  Y KA   R      L K  EA  D+ET L LE
Sbjct: 10  DCNRVLDLNSQYLKALLLRARCNNDLEKFEEAVADYETALQLE 138
>11978
          Length = 921

 Score = 33.9 bits (76), Expect = 0.24,   Method: Compositional matrix adjust.
 Identities = 28/119 (23%), Positives = 53/119 (44%), Gaps = 24/119 (20%)
 Frame = -1

Query: 132 QKALVLKEKGNKYFKQGKYDEAIE---------------------CYTKGMDADPYNPVL 170
           ++A  L+  GN++FK GKYD+A+                      C+   +  D    ++
Sbjct: 909 EQAEALRTTGNEHFKCGKYDKALRLRTTTLYATLLTPPWTSTVATCWLCALATD---VMV 739

Query: 171 PTNRASAYFRLKKFAVAESDCNLAIAL---SRTYTKAYARRGAARFALQKLEDARKDYE 226
              R++A+F LK+F    +D + A+     + +  K   RRG     L++ + A + +E
Sbjct: 738 CGCRSAAFFHLKQFHSCLADIDNALQAGFPATSLHKLLDRRGKCCLFLKRKQAAVQAFE 562
>17595
          Length = 483

 Score = 32.0 bits (71), Expect = 0.77,   Method: Compositional matrix adjust.
 Identities = 17/48 (35%), Positives = 26/48 (54%)
 Frame = -2

Query: 291 GNGFFKEGKYEQAIECYTRGIAADRTNALLPANRAMAYLKIQRYEEAE 338
           G  F K G+YEQA+  Y R ++ D   +    N A +  ++ R+ EAE
Sbjct: 275 GIVFHKTGQYEQAVASYERAVSLDNKFSHAMTNAAASLRELGRHREAE 132
>19619
          Length = 577

 Score = 30.0 bits (66), Expect = 3.3,   Method: Compositional matrix adjust.
 Identities = 15/60 (25%), Positives = 27/60 (45%)
 Frame = +3

Query: 136 VLKEKGNKYFKQGKYDEAIECYTKGMDADPYNPVLPTNRASAYFRLKKFAVAESDCNLAI 195
            L+++G  +    +Y  AIE +TK ++  P +      RA  +  L     A +D   A+
Sbjct: 174 TLRDEGEHFVHVKQYQRAIESFTKALEMKPGDKTCLVARAKCFLNLGNSEAALADSESAL 353
>18089
          Length = 438

 Score = 28.5 bits (62), Expect = 9.4,   Method: Compositional matrix adjust.
 Identities = 11/23 (47%), Positives = 17/23 (73%)
 Frame = -1

Query: 137 LKEKGNKYFKQGKYDEAIECYTK 159
           LK KGN++ K  K+ +A+E YT+
Sbjct: 69  LKNKGNEFMKAEKFSDALESYTQ 1
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|146134336|ref|NP_081093.2| RAB, member of RAS
oncogene family-like 2A [Mus musculus]
         (223 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

08428                                                                 103   6e-23
34468                                                                  95   3e-20
17511                                                                  91   3e-19
14456                                                                  88   2e-18
33374                                                                  66   3e-15
01972                                                                  72   3e-15
13901                                                                  77   7e-15
26083                                                                  76   9e-15
07465                                                                  75   2e-14
05468                                                                  70   5e-13
19006                                                                  69   2e-12
11728                                                                  68   4e-12
35581                                                                  67   5e-12
11257                                                                  65   2e-11
34359                                                                  65   2e-11
33794                                                                  62   1e-10
19656                                                                  60   8e-10
13745                                                                  59   2e-09
12339                                                                  58   3e-09
32723                                                                  56   1e-08
01398                                                                  55   3e-08
07580                                                                  54   7e-08
30760                                                                  54   7e-08
00858                                                                  51   4e-07
31291                                                                  50   6e-07
13750                                                                  50   9e-07
33380                                                                  48   3e-06
27191                                                                  46   2e-05
00552                                                                  45   2e-05
26536                                                                  44   5e-05
09204                                                                  42   2e-04
36482                                                                  42   2e-04
29380                                                                  40   7e-04
08153                                                                  38   0.003
33605                                                                  38   0.004
09827                                                                  37   0.006
14775                                                                  35   0.026
32770                                                                  32   0.18 
01095                                                                  32   0.19 
10708                                                                  31   0.35 
18509                                                                  29   1.9  
11704                                                                  27   5.1  
35363                                                                  27   5.4  
02929                                                                  27   6.2  
>08428
          Length = 1109

 Score =  103 bits (256), Expect = 6e-23,   Method: Compositional matrix adjust.
 Identities = 58/162 (35%), Positives = 89/162 (54%), Gaps = 6/162 (3%)
 Frame = -3

Query: 21   NVKIICLGDSAVGKSKLMERFLMDGFQPQQLSTYALTLYKHTATVDGKTILVDFWDTAGQ 80
            +VK+  LGDS VGKS ++ RF+   ++P Q ST   +    +  VDG       WDTAGQ
Sbjct: 1071 DVKVCLLGDSGVGKSSIVLRFVTGSYRPSQESTIGASFMSKSLVVDGAGYRFQIWDTAGQ 892

Query: 81   ERFQSMHASYYHKAHACIMVFDVQRKITYKNLGTWYAELREFRPEIPCILVA---NKIDA 137
            E+F+++   YY  A A ++V+DV R  T+K++ +W  ELR F P  P I++A   NK D 
Sbjct: 891  EKFRALAPMYYRGAAAAVIVYDVTRPRTFKSVKSWIQELRSFGP--PNIVLAIAGNKCDL 718

Query: 138  D--IQMTQKNF-SFAKKFSLPLYFVSAADGTNVVKLFNDAIR 176
            +   ++ +K+   +A   S      SA    NV ++F +  R
Sbjct: 717  EELREVVEKDAQEYASSISAIFGETSAMTAVNVEEMFTELAR 592
>34468
          Length = 1502

 Score = 94.7 bits (234), Expect = 3e-20,   Method: Compositional matrix adjust.
 Identities = 63/182 (34%), Positives = 96/182 (52%), Gaps = 8/182 (4%)
 Frame = +1

Query: 23  KIICLGDSAVGKSKLMERFLMDGFQPQQLSTYALTLYKHTATVDGKTILVDFWDTAGQER 82
           KII +GDS VGK+ L  RF +  F  +  +T  +   + +  VD + + +  WDTAGQER
Sbjct: 499 KIIVIGDSNVGKTCLTYRFCLGKFPDKTEATIGVDFREKSIQVDSEHLKLQLWDTAGQER 678

Query: 83  FQ-SMHASYYHKAHACIMVFDVQRKITYKNLGTWYAEL--REFRPEIPCILVANKIDADI 139
           F+ SM   YY   HA + V+D+ +  +++N+  W  E         IP ILV NK D  +
Sbjct: 679 FRKSMVQHYYRNVHAVVFVYDMTKMSSFENMPAWIEECDRHNLTKYIPRILVGNKCDV-V 855

Query: 140 QMTQKNFSFAKKFS----LPLYFVSAADGTNVVKLFNDAIRLAVAYK-ESSQDFMDEVLQ 194
           +    N + A+KF+    +PL+  SA D      +  DAI + VA+K + S+  M   L 
Sbjct: 856 ERIAVNTNLAQKFADAHNMPLFETSAKDDEKANHV--DAIFMTVAHKLKXSKPMMPAHLS 1029

Query: 195 EL 196
           E+
Sbjct: 1030EM 1035
>17511
          Length = 483

 Score = 91.3 bits (225), Expect = 3e-19,   Method: Compositional matrix adjust.
 Identities = 45/120 (37%), Positives = 68/120 (56%), Gaps = 5/120 (4%)
 Frame = -3

Query: 22  VKIICLGDSAVGKSKLMERFLMDGFQPQQLSTYALTLYKHTATVDGKTILVDFWDTAGQE 81
           +K+I LGDS VGK+ LM +++   F  Q  +T           VD + + +  WDTAGQE
Sbjct: 364 LKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQIWDTAGQE 185

Query: 82  RFQSMHASYYHKAHACIMVFDVQRKITYKNLGTWYAE-LREFRPE----IPCILVANKID 136
           RFQS+  ++Y  A  C++VFDV    T+++L +W  E L +  P      P +++ NKID
Sbjct: 184 RFQSLGVAFYRGADCCVLVFDVTMPNTFRSLDSWRDEFLIQASPRDPENFPFVVIGNKID 5
>14456
          Length = 1867

 Score = 88.2 bits (217), Expect = 2e-18,   Method: Compositional matrix adjust.
 Identities = 53/160 (33%), Positives = 82/160 (51%), Gaps = 10/160 (6%)
 Frame = -1

Query: 27   LGDSAVGKSKLMERFLMDGFQPQQLSTYALTLYKHTATVDGKTILVDFWDTAGQERFQSM 86
            L    VGKS LM RF+ + F  Q   T  +        VD +T  +  WDTAGQERF+S+
Sbjct: 1123 LKQGGVGKSSLMNRFVSNKFDAQSFHTIGVEFLNKDVVVDDETYTMQIWDTAGQERFKSL 944

Query: 87   HASYYHKAHACIMVFDVQRKITYKNLGTW------YAELREFRPEIPCILVANKIDAD-I 139
               +Y  A  C++ F V    +++NL  W      YA++++     P +++ NKID +  
Sbjct: 943  RTPFYRGADCCLLTFSVDSMQSFRNLSMWRKEFLYYADIQD-GVTFPFVVLGNKIDVEGR 767

Query: 140  QMTQ---KNFSFAKKFSLPLYFVSAADGTNVVKLFNDAIR 176
            Q+T    +++  A   + P +  SA D TNV K F  A++
Sbjct: 766  QVTNEEARSWCTANS-NAPYFETSAKDATNVEKAFLAAVQ 650
>33374
          Length = 489

 Score = 65.9 bits (159), Expect(2) = 3e-15,   Method: Compositional matrix adjust.
 Identities = 40/111 (36%), Positives = 59/111 (53%), Gaps = 4/111 (3%)
 Frame = +1

Query: 61  HTATVDGKTILVDFWDTAGQERFQSMHASYYHKAHACIMVFDVQRKITYKNLGTWYAEL- 119
            T  +D  T+  + WDTAGQER+ S+   YY  A A I+V+D+  + T+    TW  EL 
Sbjct: 148 QTVCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNQDTFGRAKTWVKELQ 327

Query: 120 REFRPEIPCILVANKID-ADIQMT--QKNFSFAKKFSLPLYFVSAADGTNV 167
           R+  P I   L  NK D A+ +M   ++  ++A++ SL     SA    NV
Sbjct: 328 RQASPNIVIALAGNKADLANKRMVEFEEAQAYAEENSLLFMETSAKTAMNV 480

 Score = 32.3 bits (72), Expect(2) = 3e-15,   Method: Compositional matrix adjust.
 Identities = 16/33 (48%), Positives = 21/33 (63%)
 Frame = +2

Query: 23 KIICLGDSAVGKSKLMERFLMDGFQPQQLSTYA 55
          K++ LG+SAVGKS L+ RF+   F   Q ST  
Sbjct: 35 KLVLLGESAVGKSSLVLRFVKGQFHEYQESTIG 133
>01972
          Length = 2359

 Score = 72.4 bits (176), Expect(2) = 3e-15,   Method: Compositional matrix adjust.
 Identities = 36/100 (36%), Positives = 55/100 (55%), Gaps = 1/100 (1%)
 Frame = +3

Query: 73  DFWDTAGQERFQSMHASYYHKAHACIMVFDVQRKITYKNLGTWYAELREFRPEIPCILVA 132
           + WDTAGQE+F  +   YY +    +++FDV  ++TYKN+  W+ +L      IP +L  
Sbjct: 456 NVWDTAGQEKFGGLRDGYYIQGQCAVIMFDVTSRVTYKNVPNWHRDLVRVCENIPIVLCG 635

Query: 133 NKIDA-DIQMTQKNFSFAKKFSLPLYFVSAADGTNVVKLF 171
           NK+D  D ++  K   F +K +L  Y +SA    N  K F
Sbjct: 636 NKVDIKDRKVKAKAIVFHRKKNLQYYDISAKSNYNFEKPF 755

 Score = 25.4 bits (54), Expect(2) = 3e-15,   Method: Compositional matrix adjust.
 Identities = 13/48 (27%), Positives = 24/48 (50%)
 Frame = +1

Query: 7   RHCELEQEKYDTHENVKIICLGDSAVGKSKLMERFLMDGFQPQQLSTY 54
           R+  +EQE        K++ +GD  VGK+  ++R +   F+   L  +
Sbjct: 274 RNQRMEQE-----PTFKLVLVGDGGVGKTTFVKRHVTGEFEKNMLPHW 402
>13901
          Length = 962

 Score = 76.6 bits (187), Expect = 7e-15,   Method: Compositional matrix adjust.
 Identities = 43/116 (37%), Positives = 64/116 (55%), Gaps = 6/116 (5%)
 Frame = -3

Query: 6   NRHCELEQEKYDTHENV--KIICLGDSAVGKSKLMERFLMDGFQPQQLST----YALTLY 59
           N+  +L  +     E V  K+I +GD  VGK+  ++R++ D F+     T    +AL + 
Sbjct: 339 NKQSKLRTQNLIMSEEVLFKVIIIGDPTVGKTSFVQRYVNDSFRRDYKMTIGVDFALKVI 160

Query: 60  KHTATVDGKTILVDFWDTAGQERFQSMHASYYHKAHACIMVFDVQRKITYKNLGTW 115
           + +   D   I +  WD AGQERF SM   YY  AHACI++FD+ +K TY+N   W
Sbjct: 159 RWS---DKCNIKLQLWDIAGQERFTSMTRVYYKDAHACIVMFDLTQKNTYQNAIRW 1
>26083
          Length = 432

 Score = 76.3 bits (186), Expect = 9e-15,   Method: Compositional matrix adjust.
 Identities = 36/113 (31%), Positives = 63/113 (55%), Gaps = 1/113 (0%)
 Frame = +1

Query: 23  KIICLGDSAVGKSKLMERFLMDGFQPQQLSTYALTLYKHTATVDGKTILVDFWDTAGQER 82
           K++ LG+ +VGK+ L+ RF+ D F     +T  +     T  ++ +TI +  WDTAGQER
Sbjct: 82  KLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTIRLQLWDTAGQER 261

Query: 83  FQSMHASYYHKAHACIMVFDVQRKITYKNLGTWYAELREFR-PEIPCILVANK 134
           F+S+  SY   +   ++V+D+    ++     W  ++R  R  ++  +LV NK
Sbjct: 262 FRSLIPSYIRDSSVAVVVYDITNANSFHQTSKWIDDVRTERGSDVIIMLVGNK 420
>07465
          Length = 1103

 Score = 75.5 bits (184), Expect = 2e-14,   Method: Compositional matrix adjust.
 Identities = 55/199 (27%), Positives = 91/199 (45%), Gaps = 10/199 (5%)
 Frame = +3

Query: 35  SKLMERFLMDGFQPQQLSTYALTLYKHTATVDGKTILVDFWDTAGQERFQSMHASYYHKA 94
           S +++R+    F      T  +   +    V G+ + +  WDTAGQE F ++  +YY  A
Sbjct: 240 SSMIQRYCKGIFTKDYKKTIGVDFLERQIEVGGEDVRLMLWDTAGQEEFDAITKAYYRGA 419

Query: 95  HACIMVFDVQRKITYKNLGTWYAELREFRPEIPCILVANKIDA---DIQMTQKNFSFAKK 151
            AC++ F    + +++ L TW  ++ +   EI  ++V NKID     +   ++  + AKK
Sbjct: 420 QACVLAFSTVDRDSFEALETWKRKVEDEVGEIGMVIVQNKIDLIDDAVVRPEEAENLAKK 599

Query: 152 FSLPLYFVSAADGTNVVKLFNDAIRLAVAYKESSQDFMDEV-------LQELENFKLEQK 204
             L  Y  S  +  NV ++F     LA  Y       MDEV        Q L   + +  
Sbjct: 600 LRLRFYRTSVKENMNVDEVFR---YLADKYLHQLNTGMDEVNLTPQKIGQGLIQTETKNH 770

Query: 205 EEDTSGQEQSDTTKSPSPS 223
            +D SG+ + + T S  PS
Sbjct: 771 IKDRSGKHRHEGTISLQPS 827
>05468
          Length = 1558

 Score = 70.5 bits (171), Expect = 5e-13,   Method: Compositional matrix adjust.
 Identities = 38/121 (31%), Positives = 62/121 (51%), Gaps = 7/121 (5%)
 Frame = -3

Query: 23   KIICLGDSAVGKSKLMERFLMDGFQPQQLSTYALTLYKHTATVDGKTIL-VDFWDTAGQE 81
            KI+ +G+   GK+ +++R++   F     +T  +         D  T++ +  WD AGQE
Sbjct: 1535 KILVIGELGTGKTSIIKRYVHQFFSQHYRATIGVDFALKVLNWDADTLIRLQLWDIAGQE 1356

Query: 82   RFQSMHASYYHKAHACIMVFDVQRKITYKNLGTW------YAELREFRPEIPCILVANKI 135
            RF +M   YY +A    +VFDV R  T+  +  W        +L +  P +PC+L+ANK 
Sbjct: 1355 RFGNMTRVYYKEAVGAFVVFDVTRASTFDAVTKWKNDLDSKVQLADGSP-VPCVLLANKC 1179

Query: 136  D 136
            D
Sbjct: 1178 D 1176
>19006
          Length = 568

 Score = 68.9 bits (167), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 38/115 (33%), Positives = 55/115 (47%), Gaps = 1/115 (0%)
 Frame = -2

Query: 23  KIICLGDSAVGKSKLMERFLMDGFQPQQLSTYALTLYKHTATVDGKTILVDFWDTAGQER 82
           K++ +GD A GK+ L+  F  D F P+         Y     VD K + +  WDTAGQE 
Sbjct: 432 KLVIVGDGACGKTCLLIVFSKDQF-PEVYVPTVFENYVADIEVDSKQVELALWDTAGQED 256

Query: 83  FQSMHASYYHKAHACIMVFDVQRKITYKNLG-TWYAELREFRPEIPCILVANKID 136
           +  +    Y      +M F +    + +N+   W  E+R F P +P ILV NK D
Sbjct: 255 YDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVRHFCPNVPIILVGNKKD 91
>11728
          Length = 635

 Score = 67.8 bits (164), Expect = 4e-12,   Method: Compositional matrix adjust.
 Identities = 35/118 (29%), Positives = 58/118 (49%), Gaps = 1/118 (0%)
 Frame = -1

Query: 20  ENVKIICLGDSAVGKSKLMERFLMDGFQPQQLSTYALTLYKHTATVDGKTILVDFWDTAG 79
           + +K + +GD AVGK+ L+  +  + F  + + T     Y     VD K I +  WDTAG
Sbjct: 494 QAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPT-VFDNYSANVMVDSKPINLGLWDTAG 318

Query: 80  QERFQSMHASYYHKAHACIMVFDVQRKITYKNL-GTWYAELREFRPEIPCILVANKID 136
           QE +  +    Y +    ++ F +    +++N+   WY E+    P  P ILV  K+D
Sbjct: 317 QEDYDRLRPLSYPQTDVFLICFSLISPASFENVKAKWYPEVSHHCPNTPIILVGTKLD 144
>35581
          Length = 364

 Score = 67.0 bits (162), Expect = 5e-12,   Method: Compositional matrix adjust.
 Identities = 33/86 (38%), Positives = 49/86 (56%), Gaps = 1/86 (1%)
 Frame = +2

Query: 23  KIICLGDSAVGKSKLMERFLMDGFQPQQLSTYALTLYKHTATV-DGKTILVDFWDTAGQE 81
           K + LGD+ VGK+ L+ R   D F    L++        T T+  G    VD WDTAGQE
Sbjct: 50  KCVLLGDAGVGKTCLLNRLATDKFLDSPLTSLTTASLLTTVTLTSGVMASVDLWDTAGQE 229

Query: 82  RFQSMHASYYHKAHACIMVFDVQRKI 107
           R++S+ +SYY    A ++V+D + K+
Sbjct: 230 RYRSLTSSYYRDTKAVLIVYDAEHKL 307
>11257
          Length = 1102

 Score = 65.5 bits (158), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 34/122 (27%), Positives = 61/122 (50%), Gaps = 8/122 (6%)
 Frame = -2

Query: 63   ATVDGKTILVDFWDTAGQERFQSMHASYYHKAHACIMVFDVQRKITYKNLGTWYAELREF 122
              VDG+T  +  WDTAGQER++S+   +Y     C++ F V    + ++L  WY E   +
Sbjct: 1047 VVVDGETFTMQIWDTAGQERYKSLRTPFYRGTDCCLLTFSVDNLKSLQSLSDWYDEFVNY 868

Query: 123  -----RPEIPCILVANKIDADIQ--MTQKNFSFAKKF-SLPLYFVSAADGTNVVKLFNDA 174
                     P +++ NK D + +   ++  +++ +   +LP +  SA D  NV + F   
Sbjct: 867  ADIQDSASFPFVIIGNKADIEEREVSSEDAYNWCRTHGNLPYFETSAKDSLNVQQAFLAV 688

Query: 175  IR 176
            +R
Sbjct: 687  VR 682
>34359
          Length = 1042

 Score = 65.1 bits (157), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 30/80 (37%), Positives = 46/80 (57%), Gaps = 1/80 (1%)
 Frame = +3

Query: 73  DFWDTAGQERFQSMHASYYHKAHACIMVFDVQRKITYKNLGTWYAELREFRPEIPCILVA 132
           + WDTAGQE+F  +   YY +    I++FDV  ++TYKN+  W+ +L      IP +L  
Sbjct: 204 NVWDTAGQEKFGGLRDGYYIQGTCAIIMFDVTSRVTYKNVPNWHRDLVRVCENIPIVLCG 383

Query: 133 NKIDA-DIQMTQKNFSFAKK 151
           NK+D  D ++  K   F +K
Sbjct: 384 NKVDIKDRKVKAKAIVFHRK 443
>33794
          Length = 779

 Score = 62.4 bits (150), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 32/121 (26%), Positives = 64/121 (52%), Gaps = 3/121 (2%)
 Frame = -1

Query: 62  TATVDGKTILVDFWDTAGQERFQSMHASYYHKAHACIMVFDVQRKITYKNLGTWYAELRE 121
           T  ++GK + +  WDT+GQ RF ++  SY   A   I+V+D+  K ++  +  W  E+ E
Sbjct: 674 TILLEGKRVKLQIWDTSGQGRFCTIIRSYSRGAQGIILVYDITNKWSFDGIDRWLKEVEE 495

Query: 122 FRPEIPCILVANKIDADIQ---MTQKNFSFAKKFSLPLYFVSAADGTNVVKLFNDAIRLA 178
             P IP +LV N++    +     ++  ++A + ++  + +S     N+ + F +  R+A
Sbjct: 494 HAPGIPKVLVGNRLHLAYKRQVAAKQAETYASRNNMSCFEISPLCDFNIRESFCELARMA 315

Query: 179 V 179
           +
Sbjct: 314 L 312
>19656
          Length = 428

 Score = 59.7 bits (143), Expect = 8e-10,   Method: Compositional matrix adjust.
 Identities = 29/104 (27%), Positives = 51/104 (49%), Gaps = 1/104 (0%)
 Frame = +3

Query: 22  VKIICLGDSAVGKSKLMERFLMDGFQPQQLSTYALTLYKHTATVDGKTILVDFWDTAGQE 81
           +K + +GD AVGK+ L+  +  + F  + + T     Y     VDG+ + +  WDTAGQE
Sbjct: 114 IKCVVVGDGAVGKTCLLISYTTNAFPGEYIPT-VFDNYSANVMVDGRPVNLGLWDTAGQE 290

Query: 82  RFQSMHASYYHKAHACIMVFDVQRKITYKNL-GTWYAELREFRP 124
            +  +    Y +    ++ F V    +++N+   WY E+    P
Sbjct: 291 DYDRLRPLSYPQTDVFLLCFSVASPASFENIRAKWYPEVNHHCP 422
>13745
          Length = 1045

 Score = 58.9 bits (141), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 40/130 (30%), Positives = 68/130 (52%), Gaps = 11/130 (8%)
 Frame = +2

Query: 80  QERFQSMHASYYHKAHACIMVFDVQRKITYKNLGTWYAE-LREFRPE----IPCILVANK 134
           QERFQS+  ++Y  A  C++V+DV    ++KNL +W  E L +  P      P +++ NK
Sbjct: 2   QERFQSLGVAFYRGADCCVLVYDVTAPNSFKNLDSWRDEFLIQASPRDPEHFPFVVLGNK 181

Query: 135 IDADIQM--TQKNFSFAK-KFSLPLYFVSAADGTNVVKLFNDAIRLAVAYKESSQ---DF 188
           +D D +   T++   + + K  +P Y  SA +G NV   F    + A+  +  ++   DF
Sbjct: 182 VDLDNRQVSTRRAQQWCQSKNDIPYYETSAKEGINVEMAFQTIAKNALEQETEAELINDF 361

Query: 189 MDEVLQELEN 198
            D++    EN
Sbjct: 362 PDQIRLNSEN 391
>12339
          Length = 578

 Score = 57.8 bits (138), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 37/123 (30%), Positives = 61/123 (49%), Gaps = 10/123 (8%)
 Frame = -2

Query: 80  QERFQSMHASYYHKAHACIMVFDVQRKITYKNLGTWYAE-LREFRPE----IPCILVANK 134
           QERFQS+  ++Y  A  CI+V+DV    T+ +L +W  E L +  P      P +++ NK
Sbjct: 577 QERFQSLGVAFYRGADCCILVYDVTEXKTFDSLDSWQREFLNQASPRDPEHFPFVVIGNK 398

Query: 135 IDAD---IQMTQKNFSFAKKFSLPLYFVSAADGTNVVKLFNDAIRLAVAYKESSQ--DFM 189
           ID D   +   +     + K  +P +  SA +  NV + F    + A+A +   +  DF 
Sbjct: 397 IDLDNRVVTAKRGQGWCSTKGGIPYFETSAKEAINVEQAFQTVAKNALAQESEVEIDDFP 218

Query: 190 DEV 192
            E+
Sbjct: 217 SEI 209
>32723
          Length = 384

 Score = 55.8 bits (133), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 37/111 (33%), Positives = 61/111 (54%), Gaps = 4/111 (3%)
 Frame = +2

Query: 80  QERFQSMHASYYHKAHACIMVFDVQRKITYKNLGTWYAELREFR-PEIPCILVANKIDAD 138
           QERF+S+  SYY  A+A I+V+DV  + +Y++L  W  E+  +   ++   LV NKID  
Sbjct: 2   QERFRSITQSYYRSANALILVYDVCSQQSYESLPQWIHEIELYAGTKVLAFLVGNKIDQT 181

Query: 139 IQM---TQKNFSFAKKFSLPLYFVSAADGTNVVKLFNDAIRLAVAYKESSQ 186
            +    T     FA+++ +     SA +  NV KLF+      +AY+ ++Q
Sbjct: 182 DKREIPTHIGKEFAERYEMRFLETSAKEADNVEKLFS-----TIAYQLTAQ 319
>01398
          Length = 1421

 Score = 54.7 bits (130), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 31/97 (31%), Positives = 50/97 (51%), Gaps = 5/97 (5%)
 Frame = -2

Query: 80   QERFQSMHASYYHKAHACIMVFDVQRKITYKNLGTWYAELR-EFRPEIPCILV----ANK 134
            QERF+S+  SYY  +   I+V+D+ ++ T++NL  WY E R    P     LV    +++
Sbjct: 1420 QERFRSITRSYYRNSVGVIIVYDITKRSTFENLKQWYEEARNHIEPHKAIFLVLGHKSDR 1241

Query: 135  IDADIQMTQKNFSFAKKFSLPLYFVSAADGTNVVKLF 171
             DA     ++   FA+   L  +  SA  G N+  +F
Sbjct: 1240 EDARQVTAREGRRFAEMHGLKFFETSAKSGHNIEDVF 1130
>07580
          Length = 921

 Score = 53.5 bits (127), Expect = 7e-08,   Method: Compositional matrix adjust.
 Identities = 30/123 (24%), Positives = 57/123 (46%), Gaps = 5/123 (4%)
 Frame = +3

Query: 59  YKHTATVDGKTILVDFWDTAGQERFQSMHASYYHKAHACIMVFDVQRKITYKNLGTWYAE 118
           Y+    VDG+  +++  DTAG E+F +M   Y       ++ + +  + T+ +L     +
Sbjct: 171 YRKQVEVDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFLLAYSITAQSTFNDLQELREQ 350

Query: 119 LREFR--PEIPCILVANKIDAD---IQMTQKNFSFAKKFSLPLYFVSAADGTNVVKLFND 173
           +   +   ++P +LV NK D +   +    +    A+ FS      SA    NV ++F D
Sbjct: 351 ILRVKDTDDVPMLLVGNKCDLEDERVVGKDQGQGLARSFSCAFLETSAKARINVNEIFMD 530

Query: 174 AIR 176
            +R
Sbjct: 531 LVR 539
>30760
          Length = 596

 Score = 53.5 bits (127), Expect = 7e-08,   Method: Compositional matrix adjust.
 Identities = 36/122 (29%), Positives = 59/122 (48%), Gaps = 6/122 (4%)
 Frame = -1

Query: 23  KIICLGDSAVGKSKLMERFLMDGFQ-PQQ--LSTYALTLYKHTATVDGK-TILVDFWDTA 78
           K I  GDS VGKS + + F  D    P+   ++T    L K     D +  + +  +D+A
Sbjct: 524 KCIVTGDSGVGKSSICQVFHSDSAHFPKNYSMTTGVEVLVKLVNIPDSRDQVELYLFDSA 345

Query: 79  GQERFQSMHASYYHKAHACIMVFDVQRKITYKNLGTWYAELREFRPE--IPCILVANKID 136
           G+E F      ++ +    ++V+DV  + ++     W   +R  +P   IP +LVANK D
Sbjct: 344 GKEIFSENVTKFWDQPSVVMVVYDVTDETSFSGCVRWLERVRAAKPNTVIPGVLVANKTD 165

Query: 137 AD 138
            D
Sbjct: 164 LD 159
>00858
          Length = 1658

 Score = 50.8 bits (120), Expect = 4e-07,   Method: Compositional matrix adjust.
 Identities = 30/121 (24%), Positives = 56/121 (46%), Gaps = 4/121 (3%)
 Frame = -2

Query: 60   KHTATVDGKTILVDFWDTAGQERFQSMHASYYHKAHACIMVFDVQRKITYKNLGTWYAEL 119
            +    +DG+T L+D  DTAGQE   +M           + VF V    +++++  +  ++
Sbjct: 1477 RKQVVIDGETCLLDILDTAGQEEXSAMRDQCMRTGEGFLCVFAVXNLKSFEDINQYREQI 1298

Query: 120  REFR--PEIPCILVANKIDADIQMTQKNFS--FAKKFSLPLYFVSAADGTNVVKLFNDAI 175
            +  +   E+P +LV NK+D  I+  ++      A+ + +P    SA     V   F   +
Sbjct: 1297 KRVKDADEVPMVLVGNKVDLPIRNVEQRQGKHMAELYHIPYVETSAKTRQGVDDAFYTLV 1118

Query: 176  R 176
            R
Sbjct: 1117 R 1115
>31291
          Length = 446

 Score = 50.4 bits (119), Expect = 6e-07,   Method: Compositional matrix adjust.
 Identities = 21/66 (31%), Positives = 34/66 (51%), Gaps = 1/66 (1%)
 Frame = -1

Query: 72  VDFWDTAGQERFQSMHASYYHKAHACIMVFDVQRKITYKNLGT-WYAELREFRPEIPCIL 130
           +  WDTAGQE +  +    Y      ++ F +  + + KN+   WY E+R   P +P +L
Sbjct: 446 LQLWDTAGQEDYDRLRPLAYPNTDVFMLXFSLMSEASMKNVKVKWYPEIRHHDPHVPIVL 267

Query: 131 VANKID 136
           V  K+D
Sbjct: 266 VGTKLD 249
>13750
          Length = 503

 Score = 49.7 bits (117), Expect = 9e-07,   Method: Compositional matrix adjust.
 Identities = 35/143 (24%), Positives = 67/143 (46%), Gaps = 5/143 (3%)
 Frame = -2

Query: 34  KSKLMERFLMDGFQPQQLSTYALTLYK-HTATVDGKTILVDFWDTAGQERFQSMHASYYH 92
           K+ L+ R+    F  + + T A+   + + +  D   +    WDT G E ++S+  S++ 
Sbjct: 502 KTCLLRRYQKGFFMDRTMPTIAVLCSEFNESRTDPLNVRYTLWDTGGAETYRSLWVSHFR 323

Query: 93  KAHACIMVFDVQRKITYKNLGT-WYAELREFRPEIPCILVANKIDAD---IQMTQKNFSF 148
            A   ++V+DV  + ++    T W   L +  PE   I V +K D +   +  T++  +F
Sbjct: 322 GAQVALLVYDVTCEWSFLTATTVWRKALMKNIPEAQVIFVGSKTDLEENRVISTERGQAF 143

Query: 149 AKKFSLPLYFVSAADGTNVVKLF 171
           A +     +  S+  G NV  +F
Sbjct: 142 ATQCGYTFFETSSVTGKNVDAVF 74
>33380
          Length = 282

 Score = 48.1 bits (113), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 21/70 (30%), Positives = 41/70 (58%), Gaps = 1/70 (1%)
 Frame = +3

Query: 68  KTILVDFWDTAGQERFQSMHASYYHKAHACIMVFDVQRKITYKNLGTWYAELREFRPE-I 126
           K + +  WDTAGQER++++  +YY  A   I+++DV  + ++  +  W  +++ +  +  
Sbjct: 54  KRVKLQIWDTAGQERYRTITTAYYRGAMGFILMYDVTNEESFNAVQDWCTQIKTYSWDNA 233

Query: 127 PCILVANKID 136
             +LV NK D
Sbjct: 234 QVVLVGNKCD 263
>27191
          Length = 443

 Score = 45.8 bits (107), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 24/92 (26%), Positives = 42/92 (45%), Gaps = 1/92 (1%)
 Frame = +1

Query: 45  GFQPQQLSTYALTLYKHTATVDGKTILVDFWDTAGQERFQSMHASYYHKAHACIMVFDVQ 104
           G+QP     Y   +     TV+G  + V  WD +G   +  +    Y  + A  +VFDV 
Sbjct: 46  GYQPTVGVDYGFKI----QTVNGVDMRVHMWDLSGSNEYLDVRNELYTGSDAIFIVFDVS 213

Query: 105 RKITYKNLGTWYAELREFRPEIPC-ILVANKI 135
              +++ L +W  E+  F    P  ++V N++
Sbjct: 214 NTPSFEALDSWLREINRFATGSPLNVIVGNRV 309
>00552
          Length = 455

 Score = 45.4 bits (106), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 17/48 (35%), Positives = 27/48 (56%)
 Frame = -3

Query: 75  WDTAGQERFQSMHASYYHKAHACIMVFDVQRKITYKNLGTWYAELREF 122
           WDTAGQER++S+   +Y     C++ F V    + ++L  WY E   +
Sbjct: 144 WDTAGQERYKSLRTPFYRGTDCCLLTFSVDNLKSLQSLSDWYDEFVNY 1

 Score = 42.7 bits (99), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 19/48 (39%), Positives = 26/48 (54%)
 Frame = -1

Query: 22  VKIICLGDSAVGKSKLMERFLMDGFQPQQLSTYALTLYKHTATVDGKT 69
           +K++ LGD  VGKS LM RF+ + F  Q   T  +        VDG+T
Sbjct: 443 LKVVLLGDGGVGKSSLMNRFVSNKFDAQSFHTIGVEFLTKDVVVDGET 300
>26536
          Length = 829

 Score = 43.9 bits (102), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 30/108 (27%), Positives = 52/108 (48%), Gaps = 5/108 (4%)
 Frame = +2

Query: 74  FWDTAGQERFQSMHASYYHKAHACIMVFDVQRKITYKNLGTWYAELREFRPE--IPCILV 131
           F DTAGQE + SM   Y       I+V+ V    +++     +  L  F+ E  I  +L 
Sbjct: 140 FLDTAGQEEYSSMREHYTRSGDGFIVVYSVTDVTSFQEAEAVFRWLTRFQDETSIHAVLC 319

Query: 132 ANKID--ADIQMT-QKNFSFAKKFSLPLYFVSAADGTNVVKLFNDAIR 176
            NK D  +D ++T ++    A +  +  +  SA  G NV ++++  +R
Sbjct: 320 GNKTDLTSDRKVTPEEGRKMADRLGMLYFETSAKTGDNVSQVYHGLLR 463
>09204
          Length = 1051

 Score = 42.4 bits (98), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 28/98 (28%), Positives = 43/98 (43%), Gaps = 7/98 (7%)
 Frame = -3

Query: 82   RFQSMHASYYHKAHACIMVFDVQRKITYKNLGTWYAELREFRPEIPCILVANKIDA---D 138
            R+++M   YY  A A I+ FD+  K ++  +  W  ELR+   E    +   K D    D
Sbjct: 1049 RYEAMSRIYYRGAKAAILCFDLTDKSSFDRIRFWIGELRQHEEECKLYICGTKFDLVHDD 870

Query: 139  IQMTQKNFSFAKKFS----LPLYFVSAADGTNVVKLFN 172
             +      S AK  +      +Y  S+  G N+ KLF 
Sbjct: 869  PERRAVPRSVAKALADDCMAEIYETSSMTGDNIEKLFT 756
>36482
          Length = 686

 Score = 42.0 bits (97), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 39/148 (26%), Positives = 68/148 (45%), Gaps = 8/148 (5%)
 Frame = +2

Query: 37  LMERFLMDGFQPQQLSTYALTLYKHTATVDGKTILVDFWDTAGQERFQSMHASYYHKAHA 96
           L  RFL   F  +   T   ++YK+   ++   + ++  DTAGQ  +      Y   A  
Sbjct: 2   LTVRFLTRRFIGEYCPTLE-SVYKYHTVIEDDDVRLEILDTAGQGTY-PWKEGYALWADC 175

Query: 97  CIMVFDVQRKITYKNLGTWYAELREFR--PEIPCILVANKIDA--DIQMTQKNFS-FAKK 151
            + V+ +  + +Y+ L     ++   R    +  +L ANK D   D Q+TQK     A++
Sbjct: 176 FVFVYSINDRQSYEELVQVKRQVESVRKSTSLTAVLAANKTDLLHDRQVTQKEGEDLAEE 355

Query: 152 FSLPLYFVSAADGTN---VVKLFNDAIR 176
               LY VSA++G+    +  +F+D  R
Sbjct: 356 IGCRLYEVSASEGSQMEAITSMFHDLYR 439
>29380
          Length = 853

 Score = 40.0 bits (92), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 29/83 (34%), Positives = 40/83 (48%), Gaps = 5/83 (6%)
 Frame = -2

Query: 94  AHACIMVFDVQRKITYKNLGTWYAELREFRPE-IPCILVANKIDADIQMTQKNF----SF 148
           A A I+V+DV    T+     W  ELR+   E +  IL  NK+D   Q    +F    SF
Sbjct: 852 ASAAIIVYDVNIADTFSRALAWVKELRQQNTESVLIILAGNKVDLATQHRAVSFEDAQSF 673

Query: 149 AKKFSLPLYFVSAADGTNVVKLF 171
           A++  L    VSA  G  V ++F
Sbjct: 672 ARENGLLFAEVSAKTGMAVNEIF 604
>08153
          Length = 1703

 Score = 38.1 bits (87), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 20/81 (24%), Positives = 38/81 (46%)
 Frame = +1

Query: 22  VKIICLGDSAVGKSKLMERFLMDGFQPQQLSTYALTLYKHTATVDGKTILVDFWDTAGQE 81
           V+I+ +G  A GK+ ++ +  +      ++ T   T+  +  TV+ K I    WD  GQ+
Sbjct: 85  VRILMVGLDAAGKTTILYKLKLG-----EIVTTIPTIGFNVETVEYKNISFTVWDVGGQD 249

Query: 82  RFQSMHASYYHKAHACIMVFD 102
           + + +   Y+      I V D
Sbjct: 250 KIRPLWRHYFQNTQGLIFVVD 312
>33605
          Length = 888

 Score = 37.7 bits (86), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 18/81 (22%), Positives = 40/81 (49%)
 Frame = +1

Query: 22  VKIICLGDSAVGKSKLMERFLMDGFQPQQLSTYALTLYKHTATVDGKTILVDFWDTAGQE 81
           V+++ LG    GK+ ++++F       + + T + TL  +  T++ +   ++ WD  GQ+
Sbjct: 499 VRLLMLGLDNAGKTTILKKF-----NGEDIDTISPTLGFNIKTLEHRGFKLNVWDVGGQQ 663

Query: 82  RFQSMHASYYHKAHACIMVFD 102
             +S   +Y+      + V D
Sbjct: 664 SLRSYWRNYFESTDGLVWVVD 726
>09827
          Length = 1201

 Score = 37.0 bits (84), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 19/83 (22%), Positives = 40/83 (48%)
 Frame = -3

Query: 20   ENVKIICLGDSAVGKSKLMERFLMDGFQPQQLSTYALTLYKHTATVDGKTILVDFWDTAG 79
            ++++I+ +G  A GK+ ++ +  +      ++ T   T+  +  TV+ K I    WD  G
Sbjct: 1118 KDMRILMVGLDAAGKTTILYKLKLG-----EIVTTIPTIGFNVETVEYKNISFTVWDVGG 954

Query: 80   QERFQSMHASYYHKAHACIMVFD 102
            Q++ + +   Y+      I V D
Sbjct: 953  QDKIRPLWRHYFQNTQGLIFVVD 885
>14775
          Length = 380

 Score = 35.0 bits (79), Expect = 0.026,   Method: Compositional matrix adjust.
 Identities = 18/71 (25%), Positives = 36/71 (50%), Gaps = 1/71 (1%)
 Frame = -2

Query: 34  KSKLMERFLMDGFQPQQLSTYALTLYK-HTATVDGKTILVDFWDTAGQERFQSMHASYYH 92
           K+ L+ R+    F  + + T A+   + + +  D   +    WDT G E ++S+  S++ 
Sbjct: 379 KTCLLRRYQKGFFMDRTMPTIAVLCSEFNESRTDPLNVRYTLWDTGGAETYRSLWVSHFR 200

Query: 93  KAHACIMVFDV 103
            A   ++V+DV
Sbjct: 199 GAQVALLVYDV 167
>32770
          Length = 387

 Score = 32.0 bits (71), Expect = 0.18,   Method: Compositional matrix adjust.
 Identities = 22/72 (30%), Positives = 32/72 (44%), Gaps = 10/72 (13%)
 Frame = +2

Query: 118 ELREFRPEIPCILVANKID---------ADIQMTQKNFSFAKKFSLPLYF-VSAADGTNV 167
           ELR++RP  P ILV  + D          D+    K    A+K     YF  SA  G+ +
Sbjct: 5   ELRDYRPGTPFILVGTQADLRHHSQPASKDMVPAHKGKKLARKVGALGYFECSALIGSGL 184

Query: 168 VKLFNDAIRLAV 179
            ++F   +  AV
Sbjct: 185 DRVFRQVVTCAV 220
>01095
          Length = 1745

 Score = 32.0 bits (71), Expect = 0.19,   Method: Compositional matrix adjust.
 Identities = 28/88 (31%), Positives = 44/88 (50%), Gaps = 4/88 (4%)
 Frame = -1

Query: 99   MVFDVQRKITYKNLGTWYAEL-REFRPEIPCILVANKID-ADIQMT--QKNFSFAKKFSL 154
            +V+D+  + T+    TW  EL R+  P I   L  NK D A+ +M   ++  ++A++ SL
Sbjct: 1745 VVYDITNQDTFGRAKTWVKELQRQASPNIVIALAGNKADLANKRMVEFEEAQAYAEENSL 1566

Query: 155  PLYFVSAADGTNVVKLFNDAIRLAVAYK 182
                 SA    NV  +F     LA+A K
Sbjct: 1565 LFMETSAKTAMNVNDIF-----LAIAKK 1497
>10708
          Length = 2775

 Score = 31.2 bits (69), Expect = 0.35,   Method: Compositional matrix adjust.
 Identities = 11/39 (28%), Positives = 18/39 (46%)
 Frame = -2

Query: 74   FWDTAGQERFQSMHASYYHKAHACIMVFDVQRKITYKNL 112
             WDTAGQE +  +    Y      +M F +    + +N+
Sbjct: 2711 LWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENI 2595
>18509
          Length = 625

 Score = 28.9 bits (63), Expect = 1.9,   Method: Compositional matrix adjust.
 Identities = 18/61 (29%), Positives = 28/61 (45%), Gaps = 2/61 (3%)
 Frame = -3

Query: 125 EIPCILVANKIDADIQMTQKNFS--FAKKFSLPLYFVSAADGTNVVKLFNDAIRLAVAYK 182
           E+P +LV NK+D  I+  ++      A+ + +P    SA     V   F   +R    YK
Sbjct: 530 EVPMVLVGNKVDLPIRNVEQRQGKHMAELYHIPYVETSAKTRQGVDDAFYTLVREIRKYK 351

Query: 183 E 183
           E
Sbjct: 350 E 348
>11704
          Length = 708

 Score = 27.3 bits (59), Expect = 5.1,   Method: Compositional matrix adjust.
 Identities = 10/19 (52%), Positives = 14/19 (73%)
 Frame = -1

Query: 5   RNRHCELEQEKYDTHENVK 23
           RNRHC+LE  +Y  H ++K
Sbjct: 426 RNRHCKLENNQYGRHCHIK 370
>35363
          Length = 407

 Score = 27.3 bits (59), Expect = 5.4,   Method: Compositional matrix adjust.
 Identities = 12/30 (40%), Positives = 16/30 (53%)
 Frame = -2

Query: 146 FSFAKKFSLPLYFVSAADGTNVVKLFNDAI 175
           ++F   FSLP Y++       V  LFND I
Sbjct: 361 YNFLPSFSLPCYYLGLVKVEYVFSLFNDII 272
>02929
          Length = 1353

 Score = 26.9 bits (58), Expect = 6.2,   Method: Compositional matrix adjust.
 Identities = 15/25 (60%), Positives = 19/25 (76%)
 Frame = +2

Query: 176 RLAVAYKESSQDFMDEVLQELENFK 200
           R+AV  K++ QD   E+LQELENFK
Sbjct: 47  RMAVERKKALQDAY-EMLQELENFK 118
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|188528894|ref|NP_542123.3| transmembrane 9
superfamily member 2 [Mus musculus]
         (662 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

28645                                                                 105   6e-23
00631                                                                  37   0.020
24115                                                                  32   1.1  
>28645
          Length = 703

 Score =  105 bits (262), Expect = 6e-23,   Method: Compositional matrix adjust.
 Identities = 65/204 (31%), Positives = 103/204 (50%), Gaps = 8/204 (3%)
 Frame = +3

Query: 148 NYQHHWIVDNMPVTWCYEVEDSQKFCNPGFPIGCYITDKGHAKDACVISSEFHERDTFYI 207
           +Y  H IVDN+P    +E+E+ +     GF +G                  F      Y+
Sbjct: 159 DYYVHLIVDNLPCATKFEMENKEPQVEQGFKLG------------------FVAGSDVYL 284

Query: 208 FNHVDIKIYYHVVETGSMGARLVAAKLEPKSFKHTHIDKPDCSGPAMDISNKA------- 260
            NH+ + + YH     +   R+V  ++EP+S     + K +  G      NK        
Sbjct: 285 NNHLKLILSYHT--ENNQDHRVVGFEVEPQSVSMNQL-KREADGTCTVNDNKKPVPQKLN 455

Query: 261 -SGEIKIAYTYSISFEEEKNIRWASRWDYILESMPHTHIQWFSIMNSLVIVLFLSGMVAM 319
             GE ++ ++Y + +   + +RWASRWD  L +M    I WFSI+NS+V+V FLSG++ M
Sbjct: 456 DKGETEVMFSYEVEWRPSE-VRWASRWDIYL-AMTDVQIHWFSIINSVVVVFFLSGILTM 629

Query: 320 IMLRTLHKDIARYNQMDSTEDAQE 343
           IM+RTL +DIA+YN+ D  ++  E
Sbjct: 630 IMVRTLRRDIAQYNKDDDLDETVE 701

 Score = 33.5 bits (75), Expect = 0.29,   Method: Compositional matrix adjust.
 Identities = 20/67 (29%), Positives = 33/67 (49%), Gaps = 3/67 (4%)
 Frame = +1

Query: 96  GQVLFGERIEPSPYKFTFNKKETCKLVCTKT--YNTEKAEDKQKLDFLKK-SMLLNYQHH 152
           G+VL G+RI  +PYK    K   C+++C     + + K    Q   F++K SM+      
Sbjct: 1   GEVLRGDRIVNTPYKVKMAKNVKCQMMCQTNAEFKSVKLTQTQAQTFIEK*SMITTST*L 180

Query: 153 WIVDNMP 159
           W +  +P
Sbjct: 181 WTICRVP 201
>00631
          Length = 1314

 Score = 37.4 bits (85), Expect = 0.020,   Method: Compositional matrix adjust.
 Identities = 23/65 (35%), Positives = 31/65 (47%)
 Frame = +2

Query: 598 TAVYFLIYAIHYFFSKLQITGTASTILYFGYTMIMVXXXXXXXXXXXXXACFWFVTKIYS 657
           TA Y  +Y+++YFF K ++ G   T  YFGY  +                   FV KIYS
Sbjct: 5   TAGYIYLYSVYYFFFKTKMYGLFQTSFYFGYMALFSLALGIMCGTVGYAGTKMFVRKIYS 184

Query: 658 VVKVD 662
            VK+D
Sbjct: 185 TVKID 199
>24115
          Length = 1058

 Score = 31.6 bits (70), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 12/54 (22%), Positives = 29/54 (53%)
 Frame = -1

Query: 31  RPGSAFYLPGLAPVNFCAEEKSNECKADIELFVNRLDSVESVLPYEYTAFDFCQ 84
           R G   +     P+N+  E+K+N+C  +  L +  +  + + +P++++  DF +
Sbjct: 962 RQGGVSWRQYYTPINYSYEKKTNKCNTNGSL-LGSIHKLHARIPHDFSQIDFVK 804
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6679557|ref|NP_033006.1| protein tyrosine
phosphatase, receptor type, A [Mus musculus]
         (829 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

30741                                                                 105   6e-23
17840                                                                 100   2e-21
19962                                                                  92   9e-19
15655                                                                  87   2e-17
29613                                                                  80   3e-15
17631                                                                  76   7e-14
14634                                                                  62   9e-10
07196                                                                  52   8e-07
19713                                                                  52   8e-07
30215                                                                  44   2e-04
02498                                                                  29   8.5  
>30741
          Length = 506

 Score =  105 bits (263), Expect = 6e-23,   Method: Composition-based stats.
 Identities = 55/133 (41%), Positives = 75/133 (56%), Gaps = 1/133 (0%)
 Frame = -3

Query: 394 VSVEDVTVLVDYTVRKFCIQQVGDVTNRKPQRLITQFHFTSWPDFGVPFTPIGMLKFLKK 453
           V V   +VL DY +R      V D+      R+I  FHF  WPD G P     +L F+  
Sbjct: 498 VQVRSQSVLPDYNIR------VIDIKLGSQSRMIKHFHFMRWPDHGCPERTSMLLNFVSS 337

Query: 454 VKACNPQY-AGAIVVHCSAGVGRTGTFVVIDAMLDMMHSERKVDVYGFVSRIRAQRCQMV 512
           V+A  P   AG  +VHCSAGVGRTGTF+ +D +L  +  + +VD++  V  +R  R  MV
Sbjct: 336 VRAHMPHTGAGPTLVHCSAGVGRTGTFIALDRLLLQIRQQTEVDIFNLVLTMRDNRMYMV 157

Query: 513 QTDMQYVFIYQAL 525
           QT+ QYV+I+  L
Sbjct: 156 QTENQYVYIHDCL 118

 Score = 93.6 bits (231), Expect = 3e-19,   Method: Composition-based stats.
 Identities = 43/133 (32%), Positives = 76/133 (57%)
 Frame = -3

Query: 685 ITVELKKEEECESYTVRDLLVTNTRENKSRQIRQFHFHGWPEVGIPSDGKGMINIIAAVQ 744
           + V+++ +     Y +R  ++     ++SR I+ FHF  WP+ G P     ++N +++V+
Sbjct: 504 LMVQVRSQSVLPDYNIR--VIDIKLGSQSRMIKHFHFMRWPDHGCPERTSMLLNFVSSVR 331

Query: 745 KQQQQSGNHPITVHCSAGAGRTGTFCALSTVLERVKAEGILDVFQTVKSLRLQRPHMVQT 804
                +G  P  VHCSAG GRTGTF AL  +L +++ +  +D+F  V ++R  R +MVQT
Sbjct: 330 AHMPHTGAGPTLVHCSAGVGRTGTFIALDRLLLQIRQQTEVDIFNLVLTMRDNRMYMVQT 151

Query: 805 LEQYEFCYKVVQE 817
             QY + +  + +
Sbjct: 150 ENQYVYIHDCLSD 112
>17840
          Length = 437

 Score =  100 bits (250), Expect = 2e-21,   Method: Compositional matrix adjust.
 Identities = 50/105 (47%), Positives = 72/105 (68%)
 Frame = +1

Query: 436 PDFGVPFTPIGMLKFLKKVKACNPQYAGAIVVHCSAGVGRTGTFVVIDAMLDMMHSERKV 495
           PD+ +P     +L+F++K  ACNP   G IVVHCSAGVGRTGT+++ID+M+  +  +  V
Sbjct: 4   PDYTLP-----VLEFVQKSAACNPPDGGPIVVHCSAGVGRTGTYILIDSMIRQIGDKHTV 168

Query: 496 DVYGFVSRIRAQRCQMVQTDMQYVFIYQALLEHYLYGDTELEVTS 540
           ++ GF   IR QR  +VQT+ QY+FI+  L+E YL G  + EVT+
Sbjct: 169 NIPGFTLHIRRQRNLLVQTEDQYMFIHDVLVE-YLMGGGQTEVTN 300

 Score = 56.6 bits (135), Expect = 4e-08,   Method: Compositional matrix adjust.
 Identities = 25/66 (37%), Positives = 42/66 (63%)
 Frame = +1

Query: 754 PITVHCSAGAGRTGTFCALSTVLERVKAEGILDVFQTVKSLRLQRPHMVQTLEQYEFCYK 813
           PI VHCSAG GRTGT+  + +++ ++  +  +++      +R QR  +VQT +QY F + 
Sbjct: 73  PIVVHCSAGVGRTGTYILIDSMIRQIGDKHTVNIPGFTLHIRRQRNLLVQTEDQYMFIHD 252

Query: 814 VVQEYI 819
           V+ EY+
Sbjct: 253 VLVEYL 270
>19962
          Length = 410

 Score = 92.0 bits (227), Expect = 9e-19,   Method: Composition-based stats.
 Identities = 51/134 (38%), Positives = 70/134 (52%), Gaps = 1/134 (0%)
 Frame = +1

Query: 388 TYGNVRVSVEDVTVLVDYTVRKFCIQQVGDV-TNRKPQRLITQFHFTSWPDFGVPFTPIG 446
           T G   V+   V     +  R   + Q  D  T     R +   HFT+WPD GVP  P+ 
Sbjct: 10  TLGRYTVTSTKVFHRAHFVHRLLTVSQATDQNTGGGVSREVHLLHFTAWPDHGVP-CPVT 186

Query: 447 MLKFLKKVKACNPQYAGAIVVHCSAGVGRTGTFVVIDAMLDMMHSERKVDVYGFVSRIRA 506
           +++F   V     Q +G ++VHCSAG+GRTGT++ +D +     +  KV V+  V RIR 
Sbjct: 187 LVRFWSYVTRQPAQLSGPLLVHCSAGIGRTGTYIALDMLTHQAETTGKVSVFPTVRRIRG 366

Query: 507 QRCQMVQTDMQYVF 520
           QR  MVQT  QY F
Sbjct: 367 QRVNMVQTISQYRF 408

 Score = 82.4 bits (202), Expect = 7e-16,   Method: Composition-based stats.
 Identities = 46/113 (40%), Positives = 64/113 (56%), Gaps = 1/113 (0%)
 Frame = +1

Query: 699 TVRDLLVTNTRENKSRQIRQFHFHGWPEVGIPSDGKGMINIIAAVQKQQQQ-SGNHPITV 757
           TV      NT    SR++   HF  WP+ G+P     ++   + V +Q  Q SG  P+ V
Sbjct: 79  TVSQATDQNTGGGVSREVHLLHFTAWPDHGVPCPVT-LVRFWSYVTRQPAQLSG--PLLV 249

Query: 758 HCSAGAGRTGTFCALSTVLERVKAEGILDVFQTVKSLRLQRPHMVQTLEQYEF 810
           HCSAG GRTGT+ AL  +  + +  G + VF TV+ +R QR +MVQT+ QY F
Sbjct: 250 HCSAGIGRTGTYIALDMLTHQAETTGKVSVFPTVRRIRGQRVNMVQTISQYRF 408
>15655
          Length = 467

 Score = 87.4 bits (215), Expect = 2e-17,   Method: Compositional matrix adjust.
 Identities = 58/158 (36%), Positives = 76/158 (48%), Gaps = 15/158 (9%)
 Frame = +1

Query: 371 ERKECKCAQYWP--DQGCWTYGNVRVSVEDVTVLVDYTVRKFCIQQVGDVTNRKPQRLIT 428
           ER+  KC QYWP  +Q    +    V  + V    +Y   K  ++     T     R +T
Sbjct: 7   ERQRMKCGQYWPFEEQSDEQFEEFLVDNKSVQTYKNYVETKLILRN----TETDEWREVT 174

Query: 429 QFHFTSWPDFGVPFTPIGMLKFL---KKVKACNPQYAGA----------IVVHCSAGVGR 475
              F SWPD+G+P    G L FL   ++V+A      GA          IVVHCSAG+GR
Sbjct: 175 HLQFISWPDYGIP-PATGFLDFLFHVREVQASATTKMGASWAGHPLGPPIVVHCSAGIGR 351

Query: 476 TGTFVVIDAMLDMMHSERKVDVYGFVSRIRAQRCQMVQ 513
           TGTF+ ID  L  +     VDV   V RIR+QR   +Q
Sbjct: 352 TGTFITIDISLRRLEDTGTVDVPVTVRRIRSQRAFSIQ 465

 Score = 84.7 bits (208), Expect = 1e-16,   Method: Compositional matrix adjust.
 Identities = 50/154 (32%), Positives = 78/154 (50%), Gaps = 14/154 (9%)
 Frame = +1

Query: 664 ERGQEKCAQYWPSDGLVS--YGDITVELKKEEECESYTVRDLLVTNTRENKSRQIRQFHF 721
           ER + KC QYWP +      + +  V+ K  +  ++Y    L++ NT  ++ R++    F
Sbjct: 7   ERQRMKCGQYWPFEEQSDEQFEEFLVDNKSVQTYKNYVETKLILRNTETDEWREVTHLQF 186

Query: 722 HGWPEVGIPSDGKGMINIIAAVQKQQQQS--------GNHP----ITVHCSAGAGRTGTF 769
             WP+ GIP    G ++ +  V++ Q  +          HP    I VHCSAG GRTGTF
Sbjct: 187 ISWPDYGIPP-ATGFLDFLFHVREVQASATTKMGASWAGHPLGPPIVVHCSAGIGRTGTF 363

Query: 770 CALSTVLERVKAEGILDVFQTVKSLRLQRPHMVQ 803
             +   L R++  G +DV  TV+ +R QR   +Q
Sbjct: 364 ITIDISLRRLEDTGTVDVPVTVRRIRSQRAFSIQ 465
>29613
          Length = 425

 Score = 80.5 bits (197), Expect = 3e-15,   Method: Compositional matrix adjust.
 Identities = 41/120 (34%), Positives = 64/120 (53%), Gaps = 3/120 (2%)
 Frame = -2

Query: 405 YTVRKFCIQQVGDVTNRKPQRLITQFHFTSWPDFGVPFTPIGMLKFLKKVKACNPQYAGA 464
           YT+R F I +          R + Q+    W D+    +P  +L F+  V+  +    G 
Sbjct: 352 YTIRTFTIYKED---QEDESRQVKQYFIPGWEDYSANLSPDDVLDFISSVRLESRGCQGP 182

Query: 465 IVVHCSAGVGRTGTFVVIDAMLDMMHSE---RKVDVYGFVSRIRAQRCQMVQTDMQYVFI 521
           +VVHCSAGVGRTGTF+ +D ++  +       +VD+Y  V  +R  R  MVQ++ QY++I
Sbjct: 181 MVVHCSAGVGRTGTFIALDFLMQFVRDHDLNDEVDIYNLVLNMRHNRPYMVQSEKQYIYI 2

 Score = 76.6 bits (187), Expect = 3e-14,   Method: Compositional matrix adjust.
 Identities = 38/115 (33%), Positives = 69/115 (60%), Gaps = 4/115 (3%)
 Frame = -2

Query: 698 YTVRDLLV-TNTRENKSRQIRQFHFHGWPEVGIPSDGKGMINIIAAVQKQQQQSGNHPIT 756
           YT+R   +    +E++SRQ++Q+   GW +         +++ I++V + + +    P+ 
Sbjct: 352 YTIRTFTIYKEDQEDESRQVKQYFIPGWEDYSANLSPDDVLDFISSV-RLESRGCQGPMV 176

Query: 757 VHCSAGAGRTGTFCALSTVLERVKAEGI---LDVFQTVKSLRLQRPHMVQTLEQY 808
           VHCSAG GRTGTF AL  +++ V+   +   +D++  V ++R  RP+MVQ+ +QY
Sbjct: 175 VHCSAGVGRTGTFIALDFLMQFVRDHDLNDEVDIYNLVLNMRHNRPYMVQSEKQY 11
>17631
          Length = 442

 Score = 75.9 bits (185), Expect = 7e-14,   Method: Composition-based stats.
 Identities = 44/141 (31%), Positives = 74/141 (52%), Gaps = 3/141 (2%)
 Frame = +2

Query: 682 YGDITVELKKEEECESYTVRDLLVTNTRENKSRQIRQFHFHGWPEVGIPSDGKGMINIIA 741
           +GD+TV LK   +    TVR L V     ++   +   H HGW   G     + ++ +++
Sbjct: 23  HGDVTVVLKSRRDLGHCTVRSLSVA-MMLHEPLHVTHVHMHGWLTEGDTVAPEDLLKVVS 199

Query: 742 AVQKQQQQSGNHPITVHCSAGAGRTGTFCALSTVLERVKAEGI---LDVFQTVKSLRLQR 798
            V +Q  +    PITVHCS+G GRTG + A+  +   V    +   +DVF    +L   R
Sbjct: 200 LV-RQAARHCQGPITVHCSSGTGRTGVYIAVDILHGLVSENSLDSEIDVFSLCHTLMTCR 376

Query: 799 PHMVQTLEQYEFCYKVVQEYI 819
           P+++Q+ +QYE+ ++ V+  I
Sbjct: 377 PNIIQSQDQYEYVHESVKVMI 439

 Score = 57.4 bits (137), Expect = 3e-08,   Method: Composition-based stats.
 Identities = 26/102 (25%), Positives = 51/102 (50%), Gaps = 3/102 (2%)
 Frame = +2

Query: 427 ITQFHFTSWPDFGVPFTPIGMLKFLKKVKACNPQYAGAIVVHCSAGVGRTGTFVVIDAML 486
           +T  H   W   G    P  +LK +  V+       G I VHCS+G GRTG ++ +D + 
Sbjct: 122 VTHVHMHGWLTEGDTVAPEDLLKVVSLVRQAARHCQGPITVHCSSGTGRTGVYIAVDILH 301

Query: 487 DMMHS---ERKVDVYGFVSRIRAQRCQMVQTDMQYVFIYQAL 525
            ++     + ++DV+     +   R  ++Q+  QY ++++++
Sbjct: 302 GLVSENSLDSEIDVFSLCHTLMTCRPNIIQSQDQYEYVHESV 427
>14634
          Length = 462

 Score = 62.0 bits (149), Expect = 9e-10,   Method: Compositional matrix adjust.
 Identities = 33/112 (29%), Positives = 58/112 (51%), Gaps = 2/112 (1%)
 Frame = +2

Query: 552 IPGTSNNGLEEEFKKLTSIK--IQNDKMRTGNLPANMKKNRVLQIIPYEFNRVIIPVKRG 609
           +P       E++FK+L  ++  +  +   +     N  KNR   I+P E  RV +     
Sbjct: 77  LPAAIIQSSEDQFKRLEELRPILSKEDTTSALEDKNAGKNRSSDILPVEQFRVCLSTA-N 253

Query: 610 EENTDYVNASFIDGYRQKDSYIASQGPLLHTIEDFWRMIWEWKSCSIVMLTE 661
            E+ DY+NA F+    ++  Y  +Q PL +T+ DFWRM+ +W+  ++V  T+
Sbjct: 254 REDGDYINAVFLPSLNRQQGYAMTQLPLHNTVVDFWRMVRDWRVSTVVRFTD 409

 Score = 51.2 bits (121), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 35/114 (30%), Positives = 53/114 (46%), Gaps = 9/114 (7%)
 Frame = +2

Query: 264 NILPFLSLAVSKDAVKALNKTTPLL---------ERRFIGKSNSRGCLSDDHSRVHLTPV 314
           ++LP   +  S+D  K L +  P+L         E +  GK+ S   L  +  RV L+  
Sbjct: 71  SVLPAAIIQSSEDQFKRLEELRPILSKEDTTSALEDKNAGKNRSSDILPVEQFRVCLSTA 250

Query: 315 EGVPDSDYINASFINGYQEKNKFIAAQGPKEETVNDFWRMIWEQNTATIVMVTN 368
               D DYINA F+     +  +   Q P   TV DFWRM+ +   +T+V  T+
Sbjct: 251 -NREDGDYINAVFLPSLNRQQGYAMTQLPLHNTVVDFWRMVRDWRVSTVVRFTD 409
>07196
          Length = 849

 Score = 52.4 bits (124), Expect = 8e-07,   Method: Compositional matrix adjust.
 Identities = 34/152 (22%), Positives = 69/152 (45%), Gaps = 4/152 (2%)
 Frame = -1

Query: 668 EKCAQYWPSDGL---VSYGDITVELKKE-EECESYTVRDLLVTNTRENKSRQIRQFHFHG 723
           E+   +WP  G    V  G+  + ++ E EE   Y VR+ ++ + + +     +      
Sbjct: 840 EEEPMFWPERGEIVEVDAGNFKLSMRDETEEHPGYIVREFILESIQYDYIFMTKVVTVLE 661

Query: 724 WPEVGIPSDGKGMINIIAAVQKQQQQSGNHPITVHCSAGAGRTGTFCALSTVLERVKAEG 783
           WP+         + +++       + +   P+ V    G  RTG FC L  + +++  + 
Sbjct: 660 WPDFSPVQ--HSVFSMVELTVDWLKTNDIGPVIVMDKYGGVRTGRFCGLWALRDQLLMDK 487

Query: 784 ILDVFQTVKSLRLQRPHMVQTLEQYEFCYKVV 815
            +DV+Q  K   L+RP ++ +LE  +F Y+ +
Sbjct: 486 AVDVYQLAKLYHLKRPGIIGSLEDLQFLYEAM 391

 Score = 38.5 bits (88), Expect = 0.011,   Method: Compositional matrix adjust.
 Identities = 37/152 (24%), Positives = 68/152 (44%), Gaps = 5/152 (3%)
 Frame = -1

Query: 380 YWPDQGCWT---YGNVRVSVEDVTV-LVDYTVRKFCIQQVGDVTNRKPQRLITQFHFTSW 435
           +WP++G       GN ++S+ D T     Y VR+F ++ +         +++T      W
Sbjct: 825 FWPERGEIVEVDAGNFKLSMRDETEEHPGYIVREFILESI-QYDYIFMTKVVTVL---EW 658

Query: 436 PDFG-VPFTPIGMLKFLKKVKACNPQYAGAIVVHCSAGVGRTGTFVVIDAMLDMMHSERK 494
           PDF  V  +   M++    V        G ++V    G  RTG F  + A+ D +  ++ 
Sbjct: 657 PDFSPVQHSVFSMVEL--TVDWLKTNDIGPVIVMDKYGGVRTGRFCGLWALRDQLLMDKA 484

Query: 495 VDVYGFVSRIRAQRCQMVQTDMQYVFIYQALL 526
           VDVY        +R  ++ +     F+Y+A++
Sbjct: 483 VDVYQLAKLYHLKRPGIIGSLEDLQFLYEAMV 388
>19713
          Length = 417

 Score = 52.4 bits (124), Expect = 8e-07,   Method: Compositional matrix adjust.
 Identities = 32/91 (35%), Positives = 51/91 (56%), Gaps = 1/91 (1%)
 Frame = +3

Query: 588 KNRVLQIIPYEFNRVIIPVKRGEENTDYVNASFIDGYRQK-DSYIASQGPLLHTIEDFWR 646
           KNR   I+PY+  RV++   +     DY+NAS+I+        ++A+Q PL  T+ DFW 
Sbjct: 99  KNRDPDIMPYDETRVVLSTTKD----DYINASWINDLAPSCPKFVATQAPLNVTMMDFWD 266

Query: 647 MIWEWKSCSIVMLTELEERGQEKCAQYWPSD 677
           M++E  S  IV +T  E    +K   Y+P++
Sbjct: 267 MVYELGSEVIVQITS-EYETSKKFPVYYPTE 356

 Score = 50.1 bits (118), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 34/103 (33%), Positives = 52/103 (50%), Gaps = 1/103 (0%)
 Frame = +3

Query: 281 LNKTTPLLERRFIGKSNSRGCLSDDHSRVHLTPVEGVPDSDYINASFINGYQEK-NKFIA 339
           L K +  + R +  K+     +  D +RV L+  +     DYINAS+IN       KF+A
Sbjct: 57  LKKQSIAIARCYPMKNRDPDIMPYDETRVVLSTTKD----DYINASWINDLAPSCPKFVA 224

Query: 340 AQGPKEETVNDFWRMIWEQNTATIVMVTNLKERKECKCAQYWP 382
            Q P   T+ DFW M++E  +  IV +T+  E  + K   Y+P
Sbjct: 225 TQAPLNVTMMDFWDMVYELGSEVIVQITSEYETSK-KFPVYYP 350
>30215
          Length = 389

 Score = 43.9 bits (102), Expect = 2e-04,   Method: Composition-based stats.
 Identities = 20/47 (42%), Positives = 27/47 (57%)
 Frame = +1

Query: 771 ALSTVLERVKAEGILDVFQTVKSLRLQRPHMVQTLEQYEFCYKVVQE 817
           A+ T L R++    LD+F  V  +R QR  M+QT +QY FCY    E
Sbjct: 10  AVDTALARIETGDELDLFDIVSEMRQQRYGMIQTQDQYLFCYTACME 150

 Score = 40.4 bits (93), Expect = 0.003,   Method: Composition-based stats.
 Identities = 18/52 (34%), Positives = 30/52 (57%)
 Frame = +1

Query: 479 FVVIDAMLDMMHSERKVDVYGFVSRIRAQRCQMVQTDMQYVFIYQALLEHYL 530
            + +D  L  + +  ++D++  VS +R QR  M+QT  QY+F Y A +E  L
Sbjct: 4   LMAVDTALARIETGDELDLFDIVSEMRQQRYGMIQTQDQYLFCYTACMEALL 159
>02498
          Length = 1955

 Score = 28.9 bits (63), Expect = 8.5,   Method: Compositional matrix adjust.
 Identities = 13/31 (41%), Positives = 20/31 (64%)
 Frame = +3

Query: 602 VIIPVKRGEENTDYVNASFIDGYRQKDSYIA 632
           VII +KR EE+ D +   +ID   Q++ Y+A
Sbjct: 738 VIISLKREEESLDNIKQYYIDCNSQEEKYVA 830
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|24418925|ref|NP_722498.1| galactosidase, beta 1-like
2 [Mus musculus]
         (652 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

33681                                                                 105   7e-23
27766                                                                  78   1e-14
35004                                                                  28   7.8  
>33681
          Length = 524

 Score =  105 bits (261), Expect = 7e-23,   Method: Compositional matrix adjust.
 Identities = 52/135 (38%), Positives = 81/135 (60%), Gaps = 1/135 (0%)
 Frame = +2

Query: 513 IDSQRKGLIGNLYLNNKALKNFKIYSLDMTKQFLQRFDMDN-WSVIPKELTFPAFFLGAL 571
           ++ QRKGL G++ ++ K + ++ + +LD  + F+ R    N W     +   P  +   L
Sbjct: 23  LNKQRKGLEGDVTIDGKFVTDWAVLALDFDEDFIFRVSQANEWKSYVPQKNSPTLYRAYL 202

Query: 572 SVGIYPSDTFLKLEGWVKGVVFVNGHNLGRYWNVGPQETLYLPGVWLDKGINKVIIFEET 631
           ++   P DTF+ ++GW KG+V VNG NLGRYWN+GPQ TL+LP  +L  G N+V++FEE 
Sbjct: 203 NIEGTPEDTFINMKGWKKGIVIVNGINLGRYWNIGPQLTLFLPAPFLKAGRNEVLVFEEF 382

Query: 632 MSGSMVQSTDIPHLG 646
            +G  +     P LG
Sbjct: 383 AAGEHMFFQTEPQLG 427
>27766
          Length = 487

 Score = 77.8 bits (190), Expect = 1e-14,   Method: Compositional matrix adjust.
 Identities = 55/162 (33%), Positives = 78/162 (48%), Gaps = 9/162 (5%)
 Frame = -1

Query: 345 AMHFNDYKADVTSYDYDAILTEAGDYTAKYTKLREL-----FGTVSGIXXXXXXELTAKM 399
           A  F  YK DVTSYDYDA L+EAGD T KY K RE+     +  +  +        T K 
Sbjct: 487 ANEFKHYKPDVTSYDYDAPLSEAGDITEKYLKTREIILEKVYKPLGIMELPAIPPNTPKK 308

Query: 400 VYEPMSPALYLSLWDAIQYMDKPVTSETPINMENLPVNNGNGQAFGYVLYETTIFSSGVL 459
            Y+ +    Y+        + K   S+T   ME   + +G GQ++GY++Y     S   L
Sbjct: 307 AYDKLKMEEYMDWNQLTSLIMKKANSDTVHPMETYKLAHGVGQSYGYIIYRKQCGSGNTL 128

Query: 460 S--GLVRDRGQVFLNR--VSIGFLDYKTTKITIPLTQGYTIL 497
              G VRDR QV LN   +++   D K  K+ +  +Q +  L
Sbjct: 127 QLPGQVRDRVQVLLNSWFITVFDSDSKPMKVDMHASQPHNQL 2
>35004
          Length = 285

 Score = 28.5 bits (62), Expect = 7.8,   Method: Composition-based stats.
 Identities = 13/31 (41%), Positives = 18/31 (58%), Gaps = 3/31 (9%)
 Frame = -3

Query: 291 VMEYWT---GWFDSWGGSHNILDSSEVLQTV 318
           +M  WT   GW DS GG +  +D +E  QT+
Sbjct: 253 IMNRWTVVDGWCDSEGGKYGSVDETETGQTI 161
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31982757|ref|NP_035946.2| Ras-GTPase-activating
protein (GAP120) SH3-domain binding protein 2 isoform a [Mus musculus]
         (482 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

26656                                                                 104   7e-23
17775                                                                  48   8e-06
03406                                                                  47   2e-05
26197                                                                  46   4e-05
03744                                                                  45   7e-05
20488                                                                  44   1e-04
02415                                                                  42   5e-04
11687                                                                  40   0.002
15371                                                                  40   0.002
14637                                                                  39   0.006
08958                                                                  38   0.007
24983                                                                  38   0.011
10194                                                                  37   0.012
13457                                                                  35   0.013
16427                                                                  37   0.022
00556                                                                  36   0.042
17175                                                                  35   0.048
12350                                                                  35   0.065
25691                                                                  33   0.17 
33504                                                                  33   0.31 
11108                                                                  32   0.71 
39789                                                                  30   3.2  
05273                                                                  29   3.8  
>26656
          Length = 458

 Score =  104 bits (260), Expect = 7e-23,   Method: Compositional matrix adjust.
 Identities = 45/76 (59%), Positives = 59/76 (77%)
 Frame = -2

Query: 11  VGREFVRQYYTLLNKAPEYLHRFYGRNSSYVHGGVDASGKPQEAVYGQNDIHHKVLSLNF 70
           VGREFVRQYYTL+++AP++LHRFY + S +VHGGV+  G+    V GQ+ IH ++L LNF
Sbjct: 232 VGREFVRQYYTLMHEAPQHLHRFYSQKSCFVHGGVEKPGEENAPVCGQHAIHQRILELNF 53

Query: 71  SECHTKIRHVDAHATL 86
            +CH KIR VD+H TL
Sbjct: 52  HDCHAKIRQVDSHPTL 5
>17775
          Length = 1282

 Score = 48.1 bits (113), Expect = 8e-06,   Method: Compositional matrix adjust.
 Identities = 29/80 (36%), Positives = 42/80 (52%), Gaps = 8/80 (10%)
 Frame = -2

Query: 323 RIIRYPDSHQLFVGNLPHDIDENELKEFFMSFGNVVELRINTKGVGGKLPNFGFVVFDDS 382
           RI RY   + L+V NL   ID+  L++ F +FG +   +I T+G  G+   FGFV F   
Sbjct: 363 RINRYQGVN-LYVKNLDDSIDDERLRKEFSNFGTITSAKIMTEG--GRSKGFGFVCFSSP 193

Query: 383 EPVQ--------RILIAKPI 394
           E           RI++AKP+
Sbjct: 192 EEATKAVTEMNGRIIVAKPL 133
>03406
          Length = 1292

 Score = 46.6 bits (109), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 27/86 (31%), Positives = 40/86 (46%)
 Frame = +3

Query: 313 DMEQNDSDNRRIIRYPDSHQLFVGNLPHDIDENELKEFFMSFGNVVELRINTKGVGGKLP 372
           D E+ + D+R+I         FVG L  +     L+E+F  FG V    + T    GK  
Sbjct: 213 DAEEENEDDRKI---------FVGGLSWETXSKHLREYFEKFGEVTSCTLKTDLDSGKSR 365

Query: 373 NFGFVVFDDSEPVQRILIAKPIMFRG 398
            FGFVVF ++  V  ++  K    +G
Sbjct: 366 GFGFVVFKEAATVDAVVKNKEHKLQG 443
>26197
          Length = 1365

 Score = 45.8 bits (107), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 23/71 (32%), Positives = 34/71 (47%)
 Frame = -2

Query: 328  PDSHQLFVGNLPHDIDENELKEFFMSFGNVVELRINTKGVGGKLPNFGFVVFDDSEPVQR 387
             D  ++FVG L  +     L+E+F  FG V    + T    GK   FGFVVF ++  V  
Sbjct: 1307 EDDRKIFVGGLSWETSSKHLREYFEKFGEVTSCTLKTDLDSGKSRGFGFVVFKEAVTVDA 1128

Query: 388  ILIAKPIMFRG 398
            ++  K    +G
Sbjct: 1127 VVKNKEHKLQG 1095
>03744
          Length = 3486

 Score = 45.1 bits (105), Expect = 7e-05,   Method: Compositional matrix adjust.
 Identities = 25/81 (30%), Positives = 38/81 (46%)
 Frame = -1

Query: 328  PDSHQLFVGNLPHDIDENELKEFFMSFGNVVELRINTKGVGGKLPNFGFVVFDDSEPVQR 387
            PD   LF+ +LP +  + +L + FM FGNVV  ++           FGFV +D     Q 
Sbjct: 3225 PDGANLFIYHLPQEFGDQDLMQMFMPFGNVVSAKVFIDKQTNLSKCFGFVSYDSPLAAQA 3046

Query: 388  ILIAKPIMFRGEVRLNVEEKK 408
             + +      G  RL V+ K+
Sbjct: 3045 AITSMNGFQIGMKRLKVQLKR 2983
>20488
          Length = 3281

 Score = 44.3 bits (103), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 25/81 (30%), Positives = 38/81 (46%)
 Frame = +2

Query: 328  PDSHQLFVGNLPHDIDENELKEFFMSFGNVVELRINTKGVGGKLPNFGFVVFDDSEPVQR 387
            PD   LF+ +LP +  + +L + FM FGNVV  ++           FGFV +D     Q 
Sbjct: 2699 PDGANLFIYHLPQEFGDQDLMQMFMPFGNVVSAKVFIDKQTNLSKCFGFVSYDSPLAAQA 2878

Query: 388  ILIAKPIMFRGEVRLNVEEKK 408
             + +      G  RL V+ K+
Sbjct: 2879 AITSMNGFQIGMKRLKVQLKR 2941
>02415
          Length = 2763

 Score = 42.0 bits (97), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 19/56 (33%), Positives = 30/56 (53%)
 Frame = -1

Query: 332  QLFVGNLPHDIDENELKEFFMSFGNVVELRINTKGVGGKLPNFGFVVFDDSEPVQR 387
            ++FVG LP+   ++ L+E+F  FG++ E  + T    GK   +GFV   D     R
Sbjct: 1923 KIFVGGLPYHTTDHSLREYFDKFGDIDEAVVITDRQTGKSRGYGFVTMADRTGADR 1756
>11687
          Length = 676

 Score = 40.4 bits (93), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 20/51 (39%), Positives = 29/51 (56%)
 Frame = +3

Query: 329 DSHQLFVGNLPHDIDENELKEFFMSFGNVVELRINTKGVGGKLPNFGFVVF 379
           DS ++FVG +P ++DENEL++ F  +G V  L I      G+     FV F
Sbjct: 144 DSIKMFVGQIPRNMDENELRKMFEDYGPVHSLNILRDKNTGQSKGCCFVTF 296

 Score = 34.7 bits (78), Expect = 0.098,   Method: Compositional matrix adjust.
 Identities = 19/66 (28%), Positives = 33/66 (50%)
 Frame = +3

Query: 314 MEQNDSDNRRIIRYPDSHQLFVGNLPHDIDENELKEFFMSFGNVVELRINTKGVGGKLPN 373
           M+  DS+ R   R  +  +LFVG L   + EN+++  F SFG++ +  +  +   G    
Sbjct: 378 MKPADSEKRNGERNVEERKLFVGMLSKKLSENDVRMLFESFGSIDDCTV-LRDSNGTSRG 554

Query: 374 FGFVVF 379
             F+ F
Sbjct: 555 CAFITF 572
>15371
          Length = 383

 Score = 40.0 bits (92), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 19/53 (35%), Positives = 28/53 (52%)
 Frame = -2

Query: 328 PDSHQLFVGNLPHDIDENELKEFFMSFGNVVELRINTKGVGGKLPNFGFVVFD 380
           PD   LF+ +LP +  + +L + FM FGNVV  ++           FGFV +D
Sbjct: 166 PDGANLFIYHLPQEFGDQDLMQMFMPFGNVVSAKVFIDKQTNLSKCFGFVSYD 8
>14637
          Length = 455

 Score = 38.5 bits (88), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 18/53 (33%), Positives = 28/53 (52%)
 Frame = -1

Query: 328 PDSHQLFVGNLPHDIDENELKEFFMSFGNVVELRINTKGVGGKLPNFGFVVFD 380
           PD   LF+ +LP +  + +L + FM FGNV+  ++           FGFV +D
Sbjct: 212 PDGSNLFIYHLPQEFGDQDLMQMFMPFGNVISAKVFIDKQTNLSKCFGFVSYD 54
>08958
          Length = 680

 Score = 38.1 bits (87), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 22/58 (37%), Positives = 32/58 (55%)
 Frame = +2

Query: 323 RIIRYPDSHQLFVGNLPHDIDENELKEFFMSFGNVVELRINTKGVGGKLPNFGFVVFD 380
           R  ++    +LFVGNL  D+ E++ K+ F  FG V E  +N+ G G     FGF+  D
Sbjct: 44  RRKKFTGRCRLFVGNLTPDVSEDDFKKLFSPFGEVSEAYVNS-GRG-----FGFIRLD 199
>24983
          Length = 433

 Score = 37.7 bits (86), Expect = 0.011,   Method: Composition-based stats.
 Identities = 19/57 (33%), Positives = 29/57 (50%)
 Frame = -2

Query: 331 HQLFVGNLPHDIDENELKEFFMSFGNVVELRINTKGVGGKLPNFGFVVFDDSEPVQR 387
           HQ  +G LP+   ++ L+E+F  FG++ E  + T    GK   +GFV   D     R
Sbjct: 315 HQDLLGGLPYHTTDHSLREYFDKFGDIDEAVVITDRQTGKSRGYGFVTMADRTGADR 145
>10194
          Length = 1278

 Score = 37.4 bits (85), Expect = 0.012,   Method: Compositional matrix adjust.
 Identities = 20/65 (30%), Positives = 33/65 (50%), Gaps = 4/65 (6%)
 Frame = -3

Query: 329 DSHQLFVGNLPHDIDENELKEFFMSFGNVVELRINTKGVGGKLPNFG----FVVFDDSEP 384
           D   +FVGNLP DI+E  ++  F   G+V  +R+    V  +  N G    +++F  ++ 
Sbjct: 412 DKRSVFVGNLPFDIEEESVRSHFEDCGDVENIRV----VRDRKTNLGKGICYILFKSADS 245

Query: 385 VQRIL 389
           V   L
Sbjct: 244 VSLAL 230

 Score = 34.7 bits (78), Expect = 0.079,   Method: Compositional matrix adjust.
 Identities = 15/46 (32%), Positives = 23/46 (50%)
 Frame = -3

Query: 323 RIIRYPDSHQLFVGNLPHDIDENELKEFFMSFGNVVELRINTKGVG 368
           R+ R  +   +FVGN+P   D+ +L   F  FG +  +R     VG
Sbjct: 736 RLQRANEKRTVFVGNVPLKTDKKKLARLFKQFGKIENVRFRCAPVG 599
>13457
          Length = 4857

 Score = 35.0 bits (79), Expect(2) = 0.013,   Method: Compositional matrix adjust.
 Identities = 13/37 (35%), Positives = 22/37 (59%)
 Frame = -3

Query: 326  RYPDSHQLFVGNLPHDIDENELKEFFMSFGNVVELRI 362
            R P+   LF+ +LP    + EL + F+ FGNV+  ++
Sbjct: 2437 RGPEGCNLFIYHLPQXXGDAELAQMFVPFGNVISAKV 2327

 Score = 21.2 bits (43), Expect(2) = 0.013,   Method: Compositional matrix adjust.
 Identities = 13/35 (37%), Positives = 17/35 (48%)
 Frame = -2

Query: 374  FGFVVFDDSEPVQRILIAKPIMFRGEVRLNVEEKK 408
            FGFV FD+    Q  + A      G  RL V+ K+
Sbjct: 2294 FGFVSFDNPASAQAAIQAMNGFQIGMKRLKVQLKR 2190
>16427
          Length = 1313

 Score = 36.6 bits (83), Expect = 0.022,   Method: Compositional matrix adjust.
 Identities = 25/78 (32%), Positives = 40/78 (51%), Gaps = 3/78 (3%)
 Frame = +1

Query: 332 QLFVGNLPHDIDENELKEFFMSFGNVVELRINTKGVGGKLPNFGFVVFD---DSEPVQRI 388
           +LFVG L  +IDE  L+  F  FG + E  +    V      FGFV ++   D+E   + 
Sbjct: 139 KLFVGGLAEEIDEKVLEREFSKFGRITESMVIRDKVRQVSRGFGFVTYENPMDAEEAVKH 318

Query: 389 LIAKPIMFRGEVRLNVEE 406
           +  K I+ +   +L+VE+
Sbjct: 319 MDGKEILGK---KLHVED 363
>00556
          Length = 2189

 Score = 35.8 bits (81), Expect = 0.042,   Method: Compositional matrix adjust.
 Identities = 15/51 (29%), Positives = 26/51 (50%)
 Frame = +3

Query: 331 HQLFVGNLPHDIDENELKEFFMSFGNVVELRINTKGVGGKLPNFGFVVFDD 381
           H++F+G LP  + E+++KE  +SFG +    +      G    F F  + D
Sbjct: 759 HKIFMGGLPSYLSEDQMKELLLSFGPLKSFNLVRDNATGLSKGFAFCEYLD 911
>17175
          Length = 512

 Score = 35.4 bits (80), Expect = 0.048,   Method: Compositional matrix adjust.
 Identities = 13/27 (48%), Positives = 21/27 (77%)
 Frame = -3

Query: 329 DSHQLFVGNLPHDIDENELKEFFMSFG 355
           DS ++FVG +P ++DENEL++ F  +G
Sbjct: 96  DSIKMFVGQIPRNMDENELRKMFEDYG 16
>12350
          Length = 975

 Score = 35.0 bits (79), Expect = 0.065,   Method: Compositional matrix adjust.
 Identities = 19/59 (32%), Positives = 30/59 (50%)
 Frame = -2

Query: 330 SHQLFVGNLPHDIDENELKEFFMSFGNVVELRINTKGVGGKLPNFGFVVFDDSEPVQRI 388
           + ++FVG    D+  ++L++FF  FG VV++ I           F FV F D E  Q +
Sbjct: 365 NRKIFVGRCTDDMTADDLRQFFSKFGEVVDVFIPR-----PFRAFAFVSFADPEVAQSL 204

 Score = 33.9 bits (76), Expect = 0.15,   Method: Compositional matrix adjust.
 Identities = 15/63 (23%), Positives = 33/63 (52%)
 Frame = -2

Query: 333 LFVGNLPHDIDENELKEFFMSFGNVVELRINTKGVGGKLPNFGFVVFDDSEPVQRILIAK 392
           L V  LP    E++L+ +F  FG+++ +++      G+   FGF+ F + E   + +  +
Sbjct: 614 LIVLGLPWKSTEDDLRSYFSQFGDLLMVQVKKDPKTGQSKGFGFIRFAEYESQLKCMAQR 435

Query: 393 PIM 395
            ++
Sbjct: 434 HMI 426
>25691
          Length = 768

 Score = 33.5 bits (75), Expect = 0.17,   Method: Compositional matrix adjust.
 Identities = 15/57 (26%), Positives = 26/57 (45%)
 Frame = -2

Query: 333 LFVGNLPHDIDENELKEFFMSFGNVVELRINTKGVGGKLPNFGFVVFDDSEPVQRIL 389
           L++  LP  + + +L+  F   GN++  RI      G     GF+ FD     +R +
Sbjct: 254 LYISGLPKSLTQLDLENLFTDCGNIITSRILYDQTTGLSKGVGFIRFDQRIEAERAI 84
>33504
          Length = 282

 Score = 32.7 bits (73), Expect = 0.31,   Method: Composition-based stats.
 Identities = 12/36 (33%), Positives = 22/36 (61%)
 Frame = +1

Query: 327 YPDSHQLFVGNLPHDIDENELKEFFMSFGNVVELRI 362
           Y DS  +F+G LP+D+ E ++   F  +G +V + +
Sbjct: 157 YKDSAWVFIGGLPYDLTEGDIICVFSQYGEIVNINL 264
>11108
          Length = 493

 Score = 31.6 bits (70), Expect = 0.71,   Method: Compositional matrix adjust.
 Identities = 17/69 (24%), Positives = 36/69 (52%)
 Frame = -1

Query: 323 RIIRYPDSHQLFVGNLPHDIDENELKEFFMSFGNVVELRINTKGVGGKLPNFGFVVFDDS 382
           R++ Y  S ++F+G +P DI E  L + F  FG++       +    +   + +++F+  
Sbjct: 310 RMLNY--SPKVFLGGIPWDISEQSLIQIFKPFGSIKVEWPGKEQQAAQPKGYVYIIFESD 137

Query: 383 EPVQRILIA 391
           + V+ +L A
Sbjct: 136 KQVKALLSA 110
>39789
          Length = 361

 Score = 29.6 bits (65), Expect = 3.2,   Method: Compositional matrix adjust.
 Identities = 19/47 (40%), Positives = 23/47 (48%)
 Frame = +1

Query: 333 LFVGNLPHDIDENELKEFFMSFGNVVELRINTKGVGGKLPNFGFVVF 379
           LFVGNL +D D+  LK+   +F      RI       K   FGFV F
Sbjct: 94  LFVGNLSYDTDQYSLKD---AFPGATAARIAKFQDTQKPRGFGFVEF 225
>05273
          Length = 1009

 Score = 29.3 bits (64), Expect = 3.8,   Method: Compositional matrix adjust.
 Identities = 13/38 (34%), Positives = 21/38 (55%)
 Frame = -1

Query: 344 ENELKEFFMSFGNVVELRINTKGVGGKLPNFGFVVFDD 381
           ++ L+E+F  FG++ E  + T    GK   +GFV   D
Sbjct: 160 DHSLREYFDKFGDIDEAVVITDRQTGKSRGYGFVTMAD 47
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|50872159|ref|NP_001002896.1| beaded filament
structural protein 2, phakinin [Mus musculus]
         (416 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

11243                                                                 104   7e-23
02016                                                                  66   3e-11
19956                                                                  35   0.076
28049                                                                  33   0.28 
21757                                                                  28   9.7  
>11243
          Length = 828

 Score =  104 bits (259), Expect = 7e-23,   Method: Compositional matrix adjust.
 Identities = 72/212 (33%), Positives = 121/212 (57%)
 Frame = -2

Query: 203 AEEEVSSLYKVIDEANLTKTDLEHQIESLKEELGFLSRSYEEDVKVLYKQLAGSELEQAD 262
           AE ++  L +V+DE  L KTDLE +IESLKEEL +L +++EE++ V+     G+   Q D
Sbjct: 827 AESDIVGLRRVLDELTLNKTDLELEIESLKEELIYLKKNHEEELAVVRSSARGNVDVQVD 648

Query: 263 VPMGTGLDDVLETIRVQWERDVEKNRAEAGALLQAKQQTEVVHVSQTQEEKLAAALSVEL 322
                 L  ++  +R Q+E  +EKNR E  A  +  Q   + H   T    L  + +  +
Sbjct: 647 SAPPVDLAQIMXDVRSQYESMMEKNRQELEACYKG-QSENLNHEVATNTAALQTSKTA-I 474

Query: 323 HDTSRQVQSLQAETESLRALKRGLENSLHDAQHWHDMELQNLGAVVGRLEAELAEIRSET 382
            D  R +QSL+ E +SL ++K  LE +L + +  +  +L +L A++ ++E EL  +RS+ 
Sbjct: 473 TDLKRTIQSLEIELQSLLSMKGALEGTLAETEAQYGAQLNHLQAMITQVEMELQNLRSDA 294

Query: 383 EQQQQERAHLLACKSQLQKDVASYHALLDREE 414
           + Q  E   LL  K++L+ ++A+Y  LL+ E+
Sbjct: 293 DHQSLEYKRLLDAKTRLEMEIATYRRLLEGED 198
>02016
          Length = 3061

 Score = 65.9 bits (159), Expect = 3e-11,   Method: Compositional matrix adjust.
 Identities = 64/218 (29%), Positives = 111/218 (50%), Gaps = 6/218 (2%)
 Frame = +3

Query: 204 EEEVSSLYKVIDEANLTKTDLEHQIESLKEELGFLSRSYEEDVKVLYKQLAGSELEQADV 263
           E++++ L K ++E  L + DLE++++SLKEE+ F S+ YE++++   +     E+EQ D 
Sbjct: 141 EKQLAKLKKQLEEETLLRVDLENRLQSLKEEINFKSQVYEQELEE-SRVRTTVEIEQVDG 317

Query: 264 PM----GTGLDDVLETIRVQWERDVEKNRAEAGALLQAKQQTEVVHVSQTQEEKLAAALS 319
            +       L + L  IR Q E D++  R E   L + K    +  +        +A+ S
Sbjct: 318 RLEHEYEQRLLEALREIRAQHESDLQTVRVELETLYENK----IADLKAQANRSNSASGS 485

Query: 320 V--ELHDTSRQVQSLQAETESLRALKRGLENSLHDAQHWHDMELQNLGAVVGRLEAELAE 377
              EL  T ++   L AE   L+A   G E  + D +     E +     + + + ELAE
Sbjct: 486 AWEELRITRKRADDLGAELAKLKAETAGFELRISDLESQLAREREEFRLRLAQKDDELAE 665

Query: 378 IRSETEQQQQERAHLLACKSQLQKDVASYHALLDREEN 415
           +R   E+Q QE + LL  K +L +++ +Y  LL+ EE+
Sbjct: 666 LRLTLEEQMQEYSDLLDIKIRLDREIDAYRKLLESEES 779
>19956
          Length = 536

 Score = 34.7 bits (78), Expect = 0.076,   Method: Compositional matrix adjust.
 Identities = 15/33 (45%), Positives = 26/33 (78%)
 Frame = -3

Query: 214 IDEANLTKTDLEHQIESLKEELGFLSRSYEEDV 246
           I+E  L + DLE++++SLKEEL F ++ YE+++
Sbjct: 135 IEEETLLRVDLENRVQSLKEELQFKAQLYEQEL 37
>28049
          Length = 358

 Score = 32.7 bits (73), Expect = 0.28,   Method: Compositional matrix adjust.
 Identities = 18/43 (41%), Positives = 29/43 (67%)
 Frame = -2

Query: 192 RYENEQPFRKAAEEEVSSLYKVIDEANLTKTDLEHQIESLKEE 234
           ++E  Q  R+ AEEE++ L KV++++   K  L+ QIE +KEE
Sbjct: 132 QFEEAQAERQHAEEELNRLKKVLEKSYTEKDQLQSQIEEIKEE 4
>21757
          Length = 684

 Score = 27.7 bits (60), Expect = 9.7,   Method: Compositional matrix adjust.
 Identities = 15/43 (34%), Positives = 22/43 (51%)
 Frame = +2

Query: 315 AAALSVELHDTSRQVQSLQAETESLRALKRGLENSLHDAQHWH 357
           +A    EL+DT   ++   AE + LR+  +  ENSLH     H
Sbjct: 278 SATTEEELYDTQIMIRVKDAELQKLRSQVKNFENSLHRTTEEH 406
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|29244458|ref|NP_808529.1| meckelin [Mus musculus]
         (995 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

38650                                                                 105   8e-23
27227                                                                 100   6e-21
18215                                                                  35   0.18 
31203                                                                  33   0.52 
02486                                                                  32   0.91 
25187                                                                  30   4.8  
19637                                                                  30   6.0  
21572                                                                  30   6.1  
06027                                                                  30   6.7  
04249                                                                  29   7.3  
23368                                                                  29   9.0  
>38650
          Length = 655

 Score =  105 bits (262), Expect = 8e-23,   Method: Compositional matrix adjust.
 Identities = 70/219 (31%), Positives = 103/219 (47%), Gaps = 6/219 (2%)
 Frame = +2

Query: 367 AYAFGTTYQQNCEISLSKLLVDFSSPV-FYDVYLEYTDEEQHRYLWPIPVLNLNLQHNKL 425
           AY FGT Y  +C I    L      P+ F+D+YL+YTD  Q R L+ IP++  +L+    
Sbjct: 2   AYVFGTYYSYSCSIKALGLWDTVKHPLEFFDIYLKYTDAGQQR-LFKIPLVMTDLRDASD 178

Query: 426 FVNQDSSSSKWLLTRRIFLVD----AVSGRENDLGNQPRVIRVATQISLSIRLVPNTKNG 481
                     W +TRR+FLVD      SG           +R A  I+L+I+L   TK+G
Sbjct: 179 NEINTGVMPDWRITRRMFLVDNQMNIPSGASGSTSQVATHVRYAKSITLNIQLQDETKDG 358

Query: 482 NIYTPLLTIAYSDIDIKNAHSQ-SAKISFSVKYEMNQGDASVHTDIXXXXXXXXXXXXXX 540
            I  P  TI Y DI  + A +  + ++SF+  Y M+         I              
Sbjct: 359 KIQIPYFTIKYDDISREAALANATVQVSFTTTYSMSWETYRRDFQIATGTLGTLATLYAG 538

Query: 541 XKTAGWKRRVGSPMIDLQTVMKFLLYYAGDLANVFFIIT 579
            +T  W +R G P ID  +++ FL + A  L+N FF+I+
Sbjct: 539 YRTWVWSKRAGRPSIDFPSIINFLFFAADSLSNTFFVIS 655
>27227
          Length = 379

 Score = 99.8 bits (247), Expect = 6e-21,   Method: Compositional matrix adjust.
 Identities = 49/114 (42%), Positives = 67/114 (58%)
 Frame = -1

Query: 591 KAQKSVSVLLPMPVQEERFVTYVGCAFAMKALQFLHKXXXXXXXXXXXXXWERPKGKVLK 650
           K Q  V ++ P  +  E ++  +G AFA++ L  LH              WERP+G    
Sbjct: 331 KRQDVVYLVHPEGLAVEEWLGLLGAAFALRCLSLLHLMVMQCSADIFLIDWERPRG---- 164

Query: 651 AVEGEGGVRSATVPVSIWRTYFVANEWNEIQTVRKINPLFQVLTTLFFLEVVGF 704
               + G ++ + PVSIWRTYFVANEWNEIQT RK+NP+ Q+++  FFL VVGF
Sbjct: 163 ISSTQDGKKTTSSPVSIWRTYFVANEWNEIQTTRKVNPVLQIISVCFFLVVVGF 2
>18215
          Length = 466

 Score = 34.7 bits (78), Expect = 0.18,   Method: Composition-based stats.
 Identities = 30/108 (27%), Positives = 41/108 (37%), Gaps = 4/108 (3%)
 Frame = +2

Query: 97  SIICKKCPENMKGVTKDGWDCISCPSGLTAEGK----CHCPTGHILVERNVSGSLLAQAT 152
           S  C  CP        D    ++CP+G  + G+      CPTG        S +   Q T
Sbjct: 89  STTCTNCPAGFACPHTDSDTKVACPAGSYSTGQQTSCTTCPTGRAC----PSTTAGPQET 256

Query: 153 CELCDESENSFTKANALGTRCVRCEPTFVNTSRSCSCSEPHTLTGGLC 200
           C        S T A++  T CV+C   F        C +P+T T   C
Sbjct: 257 C-------GSGTFADSNSTSCVQCPAGF-------ECPDPNTATQQAC 358
>31203
          Length = 1813

 Score = 33.1 bits (74), Expect = 0.52,   Method: Composition-based stats.
 Identities = 24/94 (25%), Positives = 40/94 (42%), Gaps = 6/94 (6%)
 Frame = -3

Query: 100  CKKCPENM-KGVTKDGWDCIS-----CPSGLTAEGKCHCPTGHILVERNVSGSLLAQATC 153
            C +C  +M +G  +  W  +S     C       GKC CP+ H   +    G  +   +C
Sbjct: 1790 CFRCAGSMSRGQRR--WSAVSEFG*VCRRSCV*RGKCACPSDHYTRDGKCHGRKVVGESC 1617

Query: 154  ELCDESENSFTKANALGTRCVRCEPTFVNTSRSC 187
            +  +  +NS   +N  G  C +C P F   ++ C
Sbjct: 1616 KGGECGQNSLC-SNFFGGVC-QCVPGFFEDNQQC 1521
>02486
          Length = 2075

 Score = 32.3 bits (72), Expect = 0.91,   Method: Compositional matrix adjust.
 Identities = 22/77 (28%), Positives = 38/77 (49%), Gaps = 3/77 (3%)
 Frame = -1

Query: 731  LRYAVATAIWLVIGIIQVVFFAAFYERFIEDKIRQFVDLCSMSNVSVFLLSHRCFGYYIH 790
            L Y VA  +WL+I  +++ F   FY+  + + +    DL S    S+F   H C   Y+H
Sbjct: 2060 LYYCVA--LWLLIYCLKICFLYMFYQDLM*NVVES--DLVSGDCFSLFWFVHVCTHTYMH 1893

Query: 791  GRS---VHGHADTNMEE 804
              +   +H H+ T+  +
Sbjct: 1892 AHTYSYMHTHSHTHTSQ 1842
>25187
          Length = 826

 Score = 30.0 bits (66), Expect = 4.8,   Method: Compositional matrix adjust.
 Identities = 19/54 (35%), Positives = 29/54 (53%), Gaps = 2/54 (3%)
 Frame = +3

Query: 164 TKANALGTRCVRCEPT--FVNTSRSCSCSEPHTLTGGLCFSNTGNFHQRVISTA 215
           + A  LG  C+RC+ +  F+   + CS   PH L    CFSNT +F   ++S+ 
Sbjct: 189 SPAFLLGVLCLRCQLSCLFLGLGQVCS-QAPHVL-ACCCFSNTSSFSLVMVSSC 344
>19637
          Length = 522

 Score = 29.6 bits (65), Expect = 6.0,   Method: Composition-based stats.
 Identities = 30/118 (25%), Positives = 43/118 (36%), Gaps = 6/118 (5%)
 Frame = -3

Query: 67  PCG-ANQRRDALGTSCVCLPGYHMISNNGGPSII--CKKCPENMKGVTKDGWDCISCPSG 123
           PCG  N  R       +C PGY+  SN    + +   + CP  M+           C +G
Sbjct: 427 PCGKGNYSRPGADICSICEPGYYCDSNTTSFTYMSTSRVCPAGME-----------CLAG 281

Query: 124 LTAEGKC---HCPTGHILVERNVSGSLLAQATCELCDESENSFTKANALGTRCVRCEP 178
           +  +       C TGH  +  NVS      AT   C +   +      +   CV C P
Sbjct: 280 MDRQPDLISDQCRTGHYCLFGNVS------ATPIPCPKGTYNGDIGRKMLADCVDCTP 125
>21572
          Length = 439

 Score = 29.6 bits (65), Expect = 6.1,   Method: Composition-based stats.
 Identities = 17/40 (42%), Positives = 22/40 (55%)
 Frame = +2

Query: 668 WRTYFVANEWNEIQTVRKINPLFQVLTTLFFLEVVGFKNL 707
           W + F++ E NEIQ   KI P+ Q L    FLE +  K L
Sbjct: 5   WTSIFLSRE-NEIQNKHKIYPVSQTLIWF*FLERINKKEL 121
>06027
          Length = 2155

 Score = 29.6 bits (65), Expect = 6.7,   Method: Composition-based stats.
 Identities = 11/29 (37%), Positives = 17/29 (58%)
 Frame = +1

Query: 88   HMISNNGGPSIICKKCPENMKGVTKDGWD 116
            H +S   G   I K+CPE+ +G  + GW+
Sbjct: 1783 HRMSRRWGVLFILKECPESQRGWKRGGWN 1869
>04249
          Length = 397

 Score = 29.3 bits (64), Expect = 7.3,   Method: Composition-based stats.
 Identities = 15/42 (35%), Positives = 26/42 (61%)
 Frame = -2

Query: 245 NLTSCQALGNMCVMNMNSYDSTTLDACRLFHYIFESTAGLIS 286
           ++ +C A+  +CV ++N   STTL   RL+  + E+ A +IS
Sbjct: 378 DIEACDAISLLCVAHINGLSSTTL--IRLYQ*LAENKATVIS 259
>23368
          Length = 941

 Score = 29.3 bits (64), Expect = 9.0,   Method: Compositional matrix adjust.
 Identities = 15/35 (42%), Positives = 21/35 (60%)
 Frame = -3

Query: 754 FYERFIEDKIRQFVDLCSMSNVSVFLLSHRCFGYY 788
           FYE FI  ++  F  LC+M NVS    ++ C GY+
Sbjct: 291 FYENFI-TRVATFP*LCAMINVSAVSAANYCTGYF 190
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|12963569|ref|NP_075689.1| protein phosphatase-1
regulatory subunit 7 [Mus musculus]
         (361 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

30747                                                                 103   1e-22
32760                                                                  61   8e-10
19955                                                                  59   2e-09
17623                                                                  52   3e-07
14078                                                                  49   4e-06
34576                                                                  45   4e-05
15929                                                                  44   1e-04
20802                                                                  44   1e-04
27897                                                                  39   0.002
08106                                                                  39   0.003
31609                                                                  35   0.047
18918                                                                  30   2.1  
24482                                                                  29   3.2  
01034                                                                  29   3.6  
>30747
          Length = 1168

 Score =  103 bits (256), Expect = 1e-22,   Method: Compositional matrix adjust.
 Identities = 81/258 (31%), Positives = 133/258 (51%), Gaps = 4/258 (1%)
 Frame = +3

Query: 81  DVDLTHYRIGKIEGLEVLKKVKSLCLRQNLIKCIENLEELQSLRELDLYDNQIKKIENLE 140
           +VDL    I  +  LE  +K++ L +  N I  I++LE  Q LR+L LYDN++ +++ LE
Sbjct: 207 EVDLHGTEITAVPDLEKFRKLRVLDVSGNYITKIQHLEFTQDLRDLKLYDNKVSQVQGLE 386

Query: 141 ALTELEVLDISFNMLRNI-EGIDKLTQLKKLFLVXXXXXXXXXXXXLH--QLQMLELGSN 197
           +L EL  L + +N + ++ +G++ L +LK L L             L    +  L+L +N
Sbjct: 387 SLKELCSLQLQYNQIESLGKGLNALKKLKCLRLDSNRLTKLDTNELLSCVNISTLDLSNN 566

Query: 198 RIRAIENIDTLTNLESLFLGKNKITKLQNLDALTNLTVLSVQSNRLAKIEGLQSLVNLRE 257
            I  +  +  L NLE LF+  N I KL +L     L+ L +  NRL  I G+  L  L+ 
Sbjct: 567 HITNLSALSYLPNLEELFVSGNSIQKLTDLHRCKKLSELDLSRNRLVDISGISGLPALQT 746

Query: 258 LYLSNNGIEVIEGLENNNKLTMLDIASNRIKKIENI-SHLTELQEFWMNDNLLESWSDLD 316
           L +S+N ++ +  L     L  L++  N+I ++    S   +LQ   + DN++ +W  + 
Sbjct: 747 LDMSDNRLKSVTSLGKLKSLETLNLNGNQISELLGWGSCFPKLQILKLCDNMVTAWKQVC 926

Query: 317 ELKGARSLETVYLERNPL 334
            LK    L  VYL  NP+
Sbjct: 927 CLKELGDLNEVYLAGNPV 980

 Score = 92.8 bits (229), Expect = 2e-19,   Method: Compositional matrix adjust.
 Identities = 71/218 (32%), Positives = 116/218 (53%), Gaps = 3/218 (1%)
 Frame = +3

Query: 118 EELQSLRELDLYDNQIKKIENLEALTELEVLDISFNMLRNIEGIDKLTQLKKLFLVXXXX 177
           E+   + E+DL+  +I  + +LE   +L VLD+S N +  I+ ++    L+ L L     
Sbjct: 186 EDFYKVYEVDLHGTEITAVPDLEKFRKLRVLDVSGNYITKIQHLEFTQDLRDLKLYDNKV 365

Query: 178 XXXXXXXXLHQLQMLELGSNRIRAI-ENIDTLTNLESLFLGKNKITKLQN--LDALTNLT 234
                   L +L  L+L  N+I ++ + ++ L  L+ L L  N++TKL    L +  N++
Sbjct: 366 SQVQGLESLKELCSLQLQYNQIESLGKGLNALKKLKCLRLDSNRLTKLDTNELLSCVNIS 545

Query: 235 VLSVQSNRLAKIEGLQSLVNLRELYLSNNGIEVIEGLENNNKLTMLDIASNRIKKIENIS 294
            L + +N +  +  L  L NL EL++S N I+ +  L    KL+ LD++ NR+  I  IS
Sbjct: 546 TLDLSNNHITNLSALSYLPNLEELFVSGNSIQKLTDLHRCKKLSELDLSRNRLVDISGIS 725

Query: 295 HLTELQEFWMNDNLLESWSDLDELKGARSLETVYLERN 332
            L  LQ   M+DN L+S + L +LK   SLET+ L  N
Sbjct: 726 GLPALQTLDMSDNRLKSVTSLGKLK---SLETLNLNGN 830
>32760
          Length = 556

 Score = 60.8 bits (146), Expect = 8e-10,   Method: Compositional matrix adjust.
 Identities = 28/57 (49%), Positives = 38/57 (66%), Gaps = 8/57 (14%)
 Frame = +3

Query: 309 LESWSDLDELKGARSLETVYLERNPL--------QKDPQYRRKVMLALPSVRQIDAT 357
           L +W DL + +  + L+TVY ERNP+        ++DP YRRKV LA+P +RQIDAT
Sbjct: 6   LAAWDDLRQFEPLKKLDTVYFERNPIWFDSSDSAKQDPSYRRKVKLAIPWIRQIDAT 176
>19955
          Length = 634

 Score = 59.3 bits (142), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 35/81 (43%), Positives = 53/81 (65%)
 Frame = -2

Query: 219 NKITKLQNLDALTNLTVLSVQSNRLAKIEGLQSLVNLRELYLSNNGIEVIEGLENNNKLT 278
           N IT++ +L++L  L  L +  N++ +I GL SL +LR L L  N I+ IE L+   KL 
Sbjct: 267 NAITRINHLNSLRRLIFLDLYDNQIEQIAGLSSLKSLRVLMLGKNRIKRIENLDTLIKLD 88

Query: 279 MLDIASNRIKKIENISHLTEL 299
           +LD+  N+I +IEN++HL EL
Sbjct: 87  VLDLHGNQITRIENLNHLGEL 25

 Score = 56.6 bits (135), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 46/135 (34%), Positives = 66/135 (48%)
 Frame = -2

Query: 107 RQNLIKCIENLEELQSLRELDLYDNQIKKIENLEALTELEVLDISFNMLRNIEGIDKLTQ 166
           R+ L  C   LE    LR L+   N I +I +L +L  L  LD+  N +  I G+  L  
Sbjct: 336 RRKLTVC-PILEGEDQLRLLNYQHNAITRINHLNSLRRLIFLDLYDNQIEQIAGLSSLKS 160

Query: 167 LKKLFLVXXXXXXXXXXXXLHQLQMLELGSNRIRAIENIDTLTNLESLFLGKNKITKLQN 226
           L+                      +L LG NRI+ IEN+DTL  L+ L L  N+IT+++N
Sbjct: 159 LR----------------------VLMLGKNRIKRIENLDTLIKLDVLDLHGNQITRIEN 46

Query: 227 LDALTNLTVLSVQSN 241
           L+ L  L VL++  N
Sbjct: 45  LNHLGELLVLNLAGN 1

 Score = 55.1 bits (131), Expect = 4e-08,   Method: Compositional matrix adjust.
 Identities = 35/72 (48%), Positives = 47/72 (65%)
 Frame = -2

Query: 82  VDLTHYRIGKIEGLEVLKKVKSLCLRQNLIKCIENLEELQSLRELDLYDNQIKKIENLEA 141
           +DL   +I +I GL  LK ++ L L +N IK IENL+ L  L  LDL+ NQI +IENL  
Sbjct: 216 LDLYDNQIEQIAGLSSLKSLRVLMLGKNRIKRIENLDTLIKLDVLDLHGNQITRIENLNH 37

Query: 142 LTELEVLDISFN 153
           L EL VL+++ N
Sbjct: 36  LGELLVLNLAGN 1

 Score = 53.9 bits (128), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 45/137 (32%), Positives = 70/137 (51%), Gaps = 13/137 (9%)
 Frame = -2

Query: 44  LSEQSLKDGVDRGAEDPEEEHELAVDMETINLDR---------DAED----VDLTHYRIG 90
            +E     G+      P+E    A + + +NLDR         + ED    ++  H  I 
Sbjct: 426 FAESPSAPGIPVVYRTPDER---ASNPDRLNLDRRKLTVCPILEGEDQLRLLNYQHNAIT 256

Query: 91  KIEGLEVLKKVKSLCLRQNLIKCIENLEELQSLRELDLYDNQIKKIENLEALTELEVLDI 150
           +I  L  L+++  L L  N I+ I  L  L+SLR L L  N+IK+IENL+ L +L+VLD+
Sbjct: 255 RINHLNSLRRLIFLDLYDNQIEQIAGLSSLKSLRVLMLGKNRIKRIENLDTLIKLDVLDL 76

Query: 151 SFNMLRNIEGIDKLTQL 167
             N +  IE ++ L +L
Sbjct: 75  HGNQITRIENLNHLGEL 25

 Score = 50.8 bits (120), Expect = 8e-07,   Method: Compositional matrix adjust.
 Identities = 31/78 (39%), Positives = 46/78 (58%)
 Frame = -2

Query: 186 LHQLQMLELGSNRIRAIENIDTLTNLESLFLGKNKITKLQNLDALTNLTVLSVQSNRLAK 245
           L +L  L+L  N+I  I  + +L +L  L LGKN+I +++NLD L  L VL +  N++ +
Sbjct: 234 LRRLIFLDLYDNQIEQIAGLSSLKSLRVLMLGKNRIKRIENLDTLIKLDVLDLHGNQITR 55

Query: 246 IEGLQSLVNLRELYLSNN 263
           IE L  L  L  L L+ N
Sbjct: 54  IENLNHLGELLVLNLAGN 1

 Score = 47.0 bits (110), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 41/125 (32%), Positives = 60/125 (48%)
 Frame = -2

Query: 95  LEVLKKVKSLCLRQNLIKCIENLEELQSLRELDLYDNQIKKIENLEALTELEVLDISFNM 154
           LE   +++ L  + N I  I +L  L+ L  LDLYDNQI++I  L +L  L VL +  N 
Sbjct: 309 LEGEDQLRLLNYQHNAITRINHLNSLRRLIFLDLYDNQIEQIAGLSSLKSLRVLMLGKNR 130

Query: 155 LRNIEGIDKLTQLKKLFLVXXXXXXXXXXXXLHQLQMLELGSNRIRAIENIDTLTNLESL 214
           ++ IE +D L                       +L +L+L  N+I  IEN++ L  L  L
Sbjct: 129 IKRIENLDTLI----------------------KLDVLDLHGNQITRIENLNHLGELLVL 16

Query: 215 FLGKN 219
            L  N
Sbjct: 15  NLAGN 1

 Score = 46.2 bits (108), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 37/110 (33%), Positives = 58/110 (52%)
 Frame = -2

Query: 209 TNLESLFLGKNKITKLQNLDALTNLTVLSVQSNRLAKIEGLQSLVNLRELYLSNNGIEVI 268
           +N + L L + K+T    L+    L +L+ Q N + +I  L SL  L  L L +N IE I
Sbjct: 363 SNPDRLNLDRRKLTVCPILEGEDQLRLLNYQHNAITRINHLNSLRRLIFLDLYDNQIEQI 184

Query: 269 EGLENNNKLTMLDIASNRIKKIENISHLTELQEFWMNDNLLESWSDLDEL 318
            GL +   L +L +  NRIK+IEN+  L +L    ++ N +    +L+ L
Sbjct: 183 AGLSSLKSLRVLMLGKNRIKRIENLDTLIKLDVLDLHGNQITRIENLNHL 34
>17623
          Length = 687

 Score = 52.0 bits (123), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 27/90 (30%), Positives = 50/90 (55%)
 Frame = +1

Query: 221 ITKLQNLDALTNLTVLSVQSNRLAKIEGLQSLVNLRELYLSNNGIEVIEGLENNNKLTML 280
             +L  L    N+  +++    +  + GL +L NL+EL+++   I+ IEGLE    +  L
Sbjct: 31  FPRLIGLHHFPNIHTMTIIGQSIPTLSGLNTLTNLKELWVAECQIKKIEGLEKCVLVEKL 210

Query: 281 DIASNRIKKIENISHLTELQEFWMNDNLLE 310
            +  N+I  I+N+  L +L+  W+N NL++
Sbjct: 211 YLYGNQISHIDNLHMLRQLKALWLNSNLIK 300

 Score = 39.7 bits (91), Expect(2) = 4e-07,   Method: Compositional matrix adjust.
 Identities = 26/79 (32%), Positives = 42/79 (53%)
 Frame = +1

Query: 94  GLEVLKKVKSLCLRQNLIKCIENLEELQSLRELDLYDNQIKKIENLEALTELEVLDISFN 153
           GL     + ++ +    I  +  L  L +L+EL + + QIKKIE LE    +E L +  N
Sbjct: 46  GLHHFPNIHTMTIIGQSIPTLSGLNTLTNLKELWVAECQIKKIEGLEKCVLVEKLYLYGN 225

Query: 154 MLRNIEGIDKLTQLKKLFL 172
            + +I+ +  L QLK L+L
Sbjct: 226 QISHIDNLHMLRQLKALWL 282

 Score = 31.6 bits (70), Expect(2) = 4e-07,   Method: Compositional matrix adjust.
 Identities = 22/61 (36%), Positives = 38/61 (62%), Gaps = 1/61 (1%)
 Frame = +2

Query: 199 IRAIENIDTLTNLESLFLGKNKITKL-QNLDALTNLTVLSVQSNRLAKIEGLQSLVNLRE 257
           ++ IEN+  L NL+ L L +NKI KL  +LD+  +L  L++  N ++ +  + +LV L +
Sbjct: 296 LKNIENLTHLVNLKELNLAENKIEKLGHSLDSNIHLEDLNLSGNPISSLRDVTNLVRLPQ 475

Query: 258 L 258
           L
Sbjct: 476 L 478

 Score = 42.4 bits (98), Expect(2) = 6e-06,   Method: Compositional matrix adjust.
 Identities = 34/91 (37%), Positives = 48/91 (52%)
 Frame = +1

Query: 199 IRAIENIDTLTNLESLFLGKNKITKLQNLDALTNLTVLSVQSNRLAKIEGLQSLVNLREL 258
           +    NI T+T      +G++ I  L  L+ LTNL  L V   ++ KIEGL+  V + +L
Sbjct: 49  LHHFPNIHTMT-----IIGQS-IPTLSGLNTLTNLKELWVAECQIKKIEGLEKCVLVEKL 210

Query: 259 YLSNNGIEVIEGLENNNKLTMLDIASNRIKK 289
           YL  N I  I+ L    +L  L + SN IKK
Sbjct: 211 YLYGNQISHIDNLHMLRQLKALWLNSNLIKK 303

 Score = 25.0 bits (53), Expect(2) = 6e-06,   Method: Compositional matrix adjust.
 Identities = 21/74 (28%), Positives = 30/74 (40%), Gaps = 19/74 (25%)
 Frame = +2

Query: 287 IKKIENISHLTELQEFWMNDNLLESWSDLDELKGARSLETVYLERNPLQ----------- 335
           +K IEN++HL  L+E  + +N +E       L     LE + L  NP+            
Sbjct: 296 LKNIENLTHLVNLKELNLAENKIEKLG--HSLDSNIHLEDLNLSGNPISSLRDVTNLVRL 469

Query: 336 --------KDPQYR 341
                   KDP YR
Sbjct: 470 PQLQSVSMKDPLYR 511

 Score = 33.9 bits (76), Expect = 0.10,   Method: Compositional matrix adjust.
 Identities = 29/77 (37%), Positives = 36/77 (46%)
 Frame = +1

Query: 88  RIGKIEGLEVLKKVKSLCLRQNLIKCIENLEELQSLRELDLYDNQIKKIENLEALTELEV 147
           +I KIEGLE    V+ L L  N I  I+NL  L+ L+ L L  N IKK    +   E E 
Sbjct: 160 QIKKIEGLEKCVLVEKLYLYGNQISHIDNLHMLRQLKALWLNSNLIKKH*EFDTFGESEG 339

Query: 148 LDISFNMLRNIEGIDKL 164
            + S    R I     L
Sbjct: 340 TEFS*KQNREIRSFSGL 390
>14078
          Length = 1045

 Score = 48.5 bits (114), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 32/105 (30%), Positives = 58/105 (55%), Gaps = 1/105 (0%)
 Frame = -1

Query: 252 LVNLRELYLSNNGIEVIEGLENNNKLTMLDIASNRIKKIENISH-LTELQEFWMNDNLLE 310
           L   ++L L+ N I+ IEGL     LT L +  N+++ ++  +  L ELQ   +  NL+ 
Sbjct: 370 LTQHQKLVLAANVIKRIEGLGRCAGLTTLHLRDNQLESLDGFTDDLKELQYVNLRGNLMS 191

Query: 311 SWSDLDELKGARSLETVYLERNPLQKDPQYRRKVMLALPSVRQID 355
           S  ++ +LK    L  + L  NP+  +  YR +V++AL ++ ++D
Sbjct: 190 SVKEMTKLKCLSFLRALALSENPVADEDDYRMEVLIALRTLERLD 56
>34576
          Length = 1496

 Score = 45.1 bits (105), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 56/201 (27%), Positives = 99/201 (49%), Gaps = 8/201 (3%)
 Frame = +2

Query: 115 ENLEELQSLRELDLYDNQIKKI-ENLEALTELEVLDISFNMLRNIE-GIDKLTQLKKLFL 172
           E++ EL  L+E+    NQ+  I E++   + LE+L +  N L  +      L ++ +L L
Sbjct: 29  EDIAELFELKEVYCGSNQLTLIPESICWCSNLEILSLHKNHLERLPVEFANLRKITRLIL 208

Query: 173 V-XXXXXXXXXXXXLHQLQMLELGSNRIRAI-ENIDTLTNLESLFLGKNKITKL-QNLDA 229
                         L +L+ L L  N +  I + + TL  L  L LG+N   +  +   +
Sbjct: 209 SDNNFTSVPVAIGSLTELEALLLDGNSLHEIPQELGTLKKLTHLSLGRNAFKEFPRPACS 388

Query: 230 LTNLTVLSVQSNRLAKIEG-LQSLVNLRELYLSNNGIEVIEG-LENNNKLTMLDIASNRI 287
           +T+L +L +  N++ +I   +  L++LRELY+  N + V    L    KL M D ++N +
Sbjct: 389 ITSLEILDLSDNKITEIPSDIAQLLSLRELYMKKNAVSVFCAELCALQKLQMADFSNNGL 568

Query: 288 KKI-ENISHLTELQEFWMNDN 307
             + E +S L  LQE  +++N
Sbjct: 569 LDLPEEVSVLGCLQELDLSNN 631
>15929
          Length = 1074

 Score = 43.5 bits (101), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 36/128 (28%), Positives = 63/128 (49%), Gaps = 3/128 (2%)
 Frame = +3

Query: 236 LSVQSNRLAKIEGLQSLVN-LRELYLSNNGIEVIEGLENNNKLTMLDIASNRIKKI-ENI 293
           L ++  R+  IE L + ++    +  S+N I  ++G     +L  L + +NRI +I EN+
Sbjct: 261 LDLRGYRIPVIENLGATLDQFDTIDFSDNDIRKLDGFPLLKRLKSLLLNNNRIVRIVENL 440

Query: 294 SH-LTELQEFWMNDNLLESWSDLDELKGARSLETVYLERNPLQKDPQYRRKVMLALPSVR 352
              +  +    + +N +    DLD L     LE + L RNP+     YR  V+  +PS+R
Sbjct: 441 GEVIPNINTVVLTNNNIHELGDLDPLASFTKLEYLSLMRNPVNAKKHYRLYVIFKIPSLR 620

Query: 353 QIDATYVR 360
            +D   +R
Sbjct: 621 VLDFQRIR 644

 Score = 33.1 bits (74), Expect = 0.16,   Method: Compositional matrix adjust.
 Identities = 37/116 (31%), Positives = 57/116 (49%), Gaps = 3/116 (2%)
 Frame = +3

Query: 124 RELDLYDNQIKKIENLEA-LTELEVLDISFNMLRNIEGIDKLTQLKKLFLVXXXXXXXXX 182
           RELDL   +I  IENL A L + + +D S N +R ++G   L                  
Sbjct: 255 RELDLRGYRIPVIENLGATLDQFDTIDFSDNDIRKLDGFPLLK----------------- 383

Query: 183 XXXLHQLQMLELGSNRI-RAIENI-DTLTNLESLFLGKNKITKLQNLDALTNLTVL 236
                +L+ L L +NRI R +EN+ + + N+ ++ L  N I +L +LD L + T L
Sbjct: 384 -----RLKSLLLNNNRIVRIVENLGEVIPNINTVVLTNNNIHELGDLDPLASFTKL 536
>20802
          Length = 526

 Score = 43.5 bits (101), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 32/86 (37%), Positives = 51/86 (59%), Gaps = 1/86 (1%)
 Frame = +2

Query: 80  EDVDLTHYRIGKIEGLE-VLKKVKSLCLRQNLIKCIENLEELQSLRELDLYDNQIKKIEN 138
           E+V L    I +IE L+   +++K L L+ NLI  IEN+  L+ L  L+L  N ++K+EN
Sbjct: 191 EEVTLHQQDIERIEYLDKWCRELKILYLQSNLIPKIENVSRLKKLEYLNLALNNVEKVEN 370

Query: 139 LEALTELEVLDISFNMLRNIEGIDKL 164
           LE    L+ LD++ N +  +  I+ L
Sbjct: 371 LEGCESLKKLDLTVNFVGELTSIECL 448

 Score = 36.2 bits (82), Expect = 0.023,   Method: Compositional matrix adjust.
 Identities = 23/74 (31%), Positives = 42/74 (56%)
 Frame = +2

Query: 255 LRELYLSNNGIEVIEGLENNNKLTMLDIASNRIKKIENISHLTELQEFWMNDNLLESWSD 314
           L+ LYL +N I  IE +    KL  L++A N ++K+EN+     L++  +  N +   + 
Sbjct: 257 LKILYLQSNLIPKIENVSRLKKLEYLNLALNNVEKVENLEGCESLKKLDLTVNFVGELTS 436

Query: 315 LDELKGARSLETVY 328
           ++ LKG  +LE ++
Sbjct: 437 IECLKGNYNLEELF 478

 Score = 32.0 bits (71), Expect = 0.35,   Method: Compositional matrix adjust.
 Identities = 25/68 (36%), Positives = 40/68 (58%), Gaps = 1/68 (1%)
 Frame = +2

Query: 104 LCLRQNLIKCIENLEE-LQSLRELDLYDNQIKKIENLEALTELEVLDISFNMLRNIEGID 162
           + L Q  I+ IE L++  + L+ L L  N I KIEN+  L +LE L+++ N +  +E ++
Sbjct: 197 VTLHQQDIERIEYLDKWCRELKILYLQSNLIPKIENVSRLKKLEYLNLALNNVEKVENLE 376

Query: 163 KLTQLKKL 170
               LKKL
Sbjct: 377 GCESLKKL 400
>27897
          Length = 774

 Score = 39.3 bits (90), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 24/72 (33%), Positives = 42/72 (58%), Gaps = 1/72 (1%)
 Frame = +1

Query: 196 SNRIRAIENIDTLTNLESLFLGKNKITKLQNLDALTN-LTVLSVQSNRLAKIEGLQSLVN 254
           +N I  I N++ L +L+ L L +N I     L+A+ + L  L +  N + K++GL  L  
Sbjct: 4   TNCIEKIANLNGLKHLKILSLARNNIKSFTGLEAVADTLEQLWISYNNIEKLKGLNVLKK 183

Query: 255 LRELYLSNNGIE 266
           L+ LY++NN ++
Sbjct: 184 LKVLYMANNSVK 219
>08106
          Length = 997

 Score = 39.3 bits (90), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 31/116 (26%), Positives = 53/116 (45%)
 Frame = +2

Query: 240 SNRLAKIEGLQSLVNLRELYLSNNGIEVIEGLENNNKLTMLDIASNRIKKIENISHLTEL 299
           +N + +IEGL   V+L  L+L +N +E ++G                         L EL
Sbjct: 5   ANVIKRIEGLGRCVSLATLHLRDNQLENLDGF---------------------TEELKEL 121

Query: 300 QEFWMNDNLLESWSDLDELKGARSLETVYLERNPLQKDPQYRRKVMLALPSVRQID 355
           Q   +  NLL S  +  +LK    L  + L  NP+  +  YR ++++AL  + ++D
Sbjct: 122 QYVNVRGNLLTSIKEAAKLKDLPLLRALSLAENPVADEDDYRLEILIALRCLERLD 289
>31609
          Length = 841

 Score = 35.0 bits (79), Expect = 0.047,   Method: Compositional matrix adjust.
 Identities = 31/88 (35%), Positives = 40/88 (45%), Gaps = 12/88 (13%)
 Frame = +1

Query: 255 LRELYLSNNGI------EVIEGLENNNKLTMLDIASNR------IKKIENISHLTELQEF 302
           L+ L L+NNGI         E L NN+ L  LDIASNR      +    NI H   LQ  
Sbjct: 370 LKRLLLANNGIGDPGCMAAGEMLANNSTLLELDIASNRVLDSGLVALANNIKHNETLQTL 549

Query: 303 WMNDNLLESWSDLDELKGARSLETVYLE 330
            + DNL          KGA+++    L+
Sbjct: 550 KLGDNLATG-------KGAQAVGDAILQ 612

 Score = 28.1 bits (61), Expect = 6.1,   Method: Compositional matrix adjust.
 Identities = 18/53 (33%), Positives = 31/53 (58%), Gaps = 6/53 (11%)
 Frame = +2

Query: 255 LRELYLSNN------GIEVIEGLENNNKLTMLDIASNRIKKIENISHLTELQE 301
           LREL LS+N       ++  EGL NN+ L +LD++ N I+    ++ +  ++E
Sbjct: 203 LRELDLSHNELSDGAAVQFGEGLVNNDILEVLDLSWNHIRPRGGVAIMHGVKE 361
>18918
          Length = 833

 Score = 29.6 bits (65), Expect = 2.1,   Method: Compositional matrix adjust.
 Identities = 22/71 (30%), Positives = 32/71 (45%), Gaps = 4/71 (5%)
 Frame = +3

Query: 104 LC-LRQNLIKCIENLEELQSLRELDLYDNQIKKIEN---LEALTELEVLDISFNMLRNIE 159
           +C L  N +  I+ L   Q L +LDL+ NQ+  I       AL +L  L +  N L   E
Sbjct: 15  ICILANNFLTKIDALSSCQQLVKLDLHGNQLTAIPGPSFWSALRKLRALYLHDNPLGKFE 194

Query: 160 GIDKLTQLKKL 170
            +  L+    L
Sbjct: 195 TLQSLSACPCL 227
>24482
          Length = 507

 Score = 28.9 bits (63), Expect = 3.2,   Method: Compositional matrix adjust.
 Identities = 17/39 (43%), Positives = 24/39 (61%), Gaps = 1/39 (2%)
 Frame = +2

Query: 124 RELDLYDNQIKKIENLEA-LTELEVLDISFNMLRNIEGI 161
           RELDL   +I  IENL A L + + +D S N +R ++G 
Sbjct: 344 RELDLRGYRIPVIENLGATLDQFDTIDFSDNDIRKLDGF 460
>01034
          Length = 522

 Score = 28.9 bits (63), Expect = 3.6,   Method: Compositional matrix adjust.
 Identities = 14/31 (45%), Positives = 20/31 (64%), Gaps = 1/31 (3%)
 Frame = +1

Query: 70 METINLDRDAEDVDLTHYRIGK-IEGLEVLK 99
          +   NLD + ++V+L HYRI K + GL V K
Sbjct: 46 LHVANLDANQQEVNLAHYRILKMVFGLVVFK 138
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31560030|ref|NP_077745.2| tropomyosin 1, alpha [Mus
musculus]
         (284 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

04603                                                                 102   1e-22
19700                                                                  76   2e-14
29815                                                                  73   1e-13
>04603
          Length = 1101

 Score =  102 bits (255), Expect = 1e-22,   Method: Compositional matrix adjust.
 Identities = 66/203 (32%), Positives = 116/203 (57%)
 Frame = -2

Query: 82  EADVASLNRRIQLVEEELDRAQERXXXXXXXXXXXXXXXXXXXRGMKVIESRAQKDEEKM 141
           E+++  LNRRI L+EE+L+R++ER                   R  + +E++    +E++
Sbjct: 779 ESEMQGLNRRITLLEEDLERSEERLQTATEKLEEATKAADESERVRRTVENKLFAGDERL 600

Query: 142 EIQEIQLKEAKHIAEDADRKYEEVARKLVIIXXXXXXXXXXXXXXXGKCAELEEELKTVT 201
           E  E  L+ AK  A++ + +Y+E ARKLV +                +  +LE++  T+T
Sbjct: 599 EECETDLRAAKQAAQEWEARYDESARKLVAMESDLERCEERAEVAERRVRDLEDQSHTLT 420

Query: 202 NNLKSLEAQAEKYSQKEDKYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVA 261
           N+L+SLE   EK SQ+ED YEE I+ L+ +LK+ E+RAE +ER V +L+K ++ ++E + 
Sbjct: 419 NSLRSLELCEEKASQREDSYEETIRDLTQRLKDHESRAEVSEREVKRLQKLLEQMDEDLE 240

Query: 262 HAKEENLSMHQMLDQTLLELNNM 284
             +  N  + + +DQ + +L N+
Sbjct: 239 EQRRANNCLQEEMDQCIGDLQNL 171
>19700
          Length = 608

 Score = 75.9 bits (185), Expect = 2e-14,   Method: Compositional matrix adjust.
 Identities = 48/127 (37%), Positives = 69/127 (54%)
 Frame = -1

Query: 82  EADVASLNRRIQLVEEELDRAQERXXXXXXXXXXXXXXXXXXXRGMKVIESRAQKDEEKM 141
           E+D+A LNRRIQL+EE+L+R++ER                   RG +  E +    EE++
Sbjct: 395 ESDLAGLNRRIQLLEEDLERSEERLQTATEKLEEASKAADESERGRRTAEKKMFTGEERL 216

Query: 142 EIQEIQLKEAKHIAEDADRKYEEVARKLVIIXXXXXXXXXXXXXXXGKCAELEEELKTVT 201
           E  E +L+ AK  A + + +YEEVAR+L ++                K  ELEEE  T+T
Sbjct: 215 EDVETELRTAKQAAREWESRYEEVARRLQVMDHDLGKAEYRADNSERKARELEEESLTLT 36

Query: 202 NNLKSLE 208
           NNL+SLE
Sbjct: 35  NNLRSLE 15
>29815
          Length = 337

 Score = 73.2 bits (178), Expect = 1e-13,   Method: Compositional matrix adjust.
 Identities = 38/78 (48%), Positives = 57/78 (73%)
 Frame = +2

Query: 188 GKCAELEEELKTVTNNLKSLEAQAEKYSQKEDKYEEEIKVLSDKLKEAETRAEFAERSVT 247
            KC EL+E+L  V NN+K+L  Q ++ SQ+ED YEE I+ L+ +LK+ E RA+ AER+V+
Sbjct: 41  SKCYELDEQLHVVGNNIKTLSIQNDQASQREDSYEETIRDLTQRLKDCENRAQEAERTVS 220

Query: 248 KLEKSIDDLEEKVAHAKE 265
           KL+K +D LE+++   KE
Sbjct: 221 KLQKEVDRLEDELLVEKE 274
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6677995|ref|NP_033222.1| solute carrier family 16,
member 1 [Mus musculus]
         (493 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

01833                                                                 103   1e-22
34413                                                                  37   0.015
05685                                                                  30   2.9  
29889                                                                  29   3.6  
>01833
          Length = 2427

 Score =  103 bits (257), Expect = 1e-22,   Method: Compositional matrix adjust.
 Identities = 63/190 (33%), Positives = 100/190 (52%), Gaps = 4/190 (2%)
 Frame = +2

Query: 13  PPDGGWGWAV----LVGAFISIGFSYAFPKSITVFFKEIEVIFSATTSEVSWISSIMLAV 68
           PPDGGWGW +    L+   I  G +Y F     +F  + E  F      ++   S+ +  
Sbjct: 629 PPDGGWGWVIVLASLLANIIVDGITYTF----GIFLPKFEEAFQQPKRTIALAGSLQVGT 796

Query: 69  MYAGGPISSILVNKYGSRPVMIAGGCLSGCGLIAASFCNTVQELYLCIGVIGGLGLAFNL 128
               GPI S L N++G + V + G  ++  G + + F  +   L L  G+IGG G     
Sbjct: 797 YLCAGPIVSALTNRFGCKMVTMVGSVVATAGFVLSVFAPSADILILTYGIIGGFGFGMMY 976

Query: 129 NPALTMIGKYFYKKRPLANGLAMAGSPVFLSTLAPLNQAFFDIFDWRGSFLILGGLLLNC 188
            PA+ ++G YF K+R LA G+A+ GS + +  +APL+      F ++G+ LIL G++ N 
Sbjct: 977 LPAIVIVGYYFEKRRALATGIAVCGSGIGMFIMAPLSDLLLHEFGYKGALLILAGIVFNG 1156

Query: 189 CVAGSLMRPI 198
            + G+LMRP+
Sbjct: 1157TICGALMRPL 1186

 Score = 71.2 bits (173), Expect = 8e-13,   Method: Compositional matrix adjust.
 Identities = 51/199 (25%), Positives = 88/199 (44%), Gaps = 3/199 (1%)
 Frame = +2

Query: 237  SVFQTINKFLDLSLFTHRGFLLYLSGNVVMFFGLFTPLVFLSSYGKSKDFSSEKSAFLLS 296
            S   T+ + LD S+  ++ ++L L GN+    G + P VF+         +  K+A LLS
Sbjct: 1754 SARDTLMQMLDFSIMKNKAYVLILVGNIFAMLGFYVPFVFMPEKALGLGIAEGKAAILLS 1933

Query: 297  ILAFVDMVARPSMGLAANTKWIRPRIQYFFAASVVANGVCHLLAPLSTTYVGFCVYAGVF 356
            I+   + V R   G+ AN   I   +    A  V   GV   + P    ++  CV A VF
Sbjct: 1934 IIGITNTVGRVLTGVLANMNKIDSLVINNIAMFVC--GVATFITPFCNNFILLCVIAAVF 2107

Query: 357  GF---AFGWLSSVLFETLMDLIGPQRFSSAVGLVTIVECCPVXXXXXXXXXXNDMYGDYK 413
            G    A+  LSS+L   L D++G ++ ++A G +T+                 D   D  
Sbjct: 2108 GLCVAAYISLSSIL---LCDMLGVEQLTNAFGFLTLARGVSSCAGSPMAGAIIDATQDVD 2278

Query: 414  YTYWACGVILIIAGIYLFI 432
              ++  G +++   ++ F+
Sbjct: 2279 LAFYVGGALIMFGSLFHFM 2335
>34413
          Length = 475

 Score = 37.4 bits (85), Expect = 0.015,   Method: Compositional matrix adjust.
 Identities = 24/83 (28%), Positives = 42/83 (50%)
 Frame = -3

Query: 243 NKFLDLSLFTHRGFLLYLSGNVVMFFGLFTPLVFLSSYGKSKDFSSEKSAFLLSILAFVD 302
           +KF DLSL +   +L+ L  N          ++ L S+G  + F    SA+LLS+++  D
Sbjct: 305 SKFFDLSLLSDPMYLVILISNSTNAISYTNFIILLPSFGLDRGFDKSLSAYLLSVVSTTD 126

Query: 303 MVARPSMGLAANTKWIRPRIQYF 325
           ++ R      ++  +I P+  YF
Sbjct: 125 LIGRIGGSALSDMGFI-PKTWYF 60
>05685
          Length = 733

 Score = 29.6 bits (65), Expect = 2.9,   Method: Compositional matrix adjust.
 Identities = 23/78 (29%), Positives = 35/78 (44%), Gaps = 14/78 (17%)
 Frame = +2

Query: 94  CLSGCGLIAASF-CNTVQELYLC-----------IGVIGGL-GLA-FNLNPALTMIGKYF 139
           C SGC  + +S  C+ + E+Y+C            GV   L  LA F++NP      KY+
Sbjct: 341 CASGCSAVESSRQCSPIAEMYICKHDVLNSFHGACGVFAALINLAVFSVNPLTLP**KYW 520

Query: 140 YKKRPLANGLAMAGSPVF 157
            K  P ++   +   P F
Sbjct: 521 IKTNPFSDDFFLPTQPFF 574
>29889
          Length = 438

 Score = 29.3 bits (64), Expect = 3.6,   Method: Compositional matrix adjust.
 Identities = 20/65 (30%), Positives = 30/65 (46%)
 Frame = +3

Query: 327 AASVVANGVCHLLAPLSTTYVGFCVYAGVFGFAFGWLSSVLFETLMDLIGPQRFSSAVGL 386
             S   +G C  + P  +T+  F V   + G AFG +  +L   L+DLIGP      +G 
Sbjct: 21  CGSEYCDGCCVAVCPFGSTFGEFAVILIIAGLAFGVVLGLLVVVLIDLIGPNNLGDGLGY 200

Query: 387 VTIVE 391
           V +  
Sbjct: 201 VMLAN 215
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|7305295|ref|NP_038635.1| myosin, heavy polypeptide
11, smooth muscle [Mus musculus]
         (1938 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

25944                                                                 106   1e-22
25922                                                                 105   2e-22
01074                                                                  94   6e-19
01284                                                                  87   6e-17
31878                                                                  59   3e-15
20566                                                                  52   2e-06
30605                                                                  35   0.28 
38905                                                                  31   6.3  
10536                                                                  30   8.0  
19956                                                                  30   9.9  
>25944
          Length = 417

 Score =  106 bits (264), Expect = 1e-22,   Method: Compositional matrix adjust.
 Identities = 63/138 (45%), Positives = 88/138 (63%)
 Frame = -3

Query: 1548 LEESEDDVQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELED 1607
            +EE ED++QA ED KLRLEVNM AL+ +++ ++  R+EQ EE +R L RQL E E ELED
Sbjct: 415  IEELEDELQAAEDGKLRLEVNMNALREKYKNEVAGREEQEEESKRSLLRQLREMEAELED 236

Query: 1608 EXXXXXXXXXXXXXXXXXXXXXXXXADSAIKGREEAIKQLRKLQAQMKDFQRELDDARAS 1667
            E                         + A K +E+A+KQ +K+ AQMKDFQ EL+DAR +
Sbjct: 235  ERKQRALAVNARNKLQGDVQGMEQQLEMATKVKEDAVKQYKKIFAQMKDFQHELEDARIA 56

Query: 1668 RDEIFATSKENEKKAKSL 1685
            R+++ A +K+NEKK K+L
Sbjct: 55   REDMAAQAKDNEKKVKNL 2
>25922
          Length = 422

 Score =  105 bits (261), Expect = 2e-22,   Method: Compositional matrix adjust.
 Identities = 54/132 (40%), Positives = 79/132 (59%)
 Frame = -2

Query: 394 RAILTPRIKVGRDVVQKAQTKEQADFAIEALAKATYERLFRWILSRVNKALDKTHRQGAS 453
            A++   + V  D+V    +  ++ +A +AL KA Y R+F W++ R+N ++     Q   
Sbjct: 403 HALMHRTVAVKGDMVTTDLSVSESSYARDALCKALYSRMFSWLVHRINDSIKVRGAQRTK 224

Query: 454 FLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGL 513
            +G+LDI GFE+FE NSFEQ  INY NEKLQQ+F       EQEEY +EGIEW  +++  
Sbjct: 223 VMGVLDIYGFEVFENNSFEQFIINYCNEKLQQIFIELTLKEEQEEYIKEGIEWIHVEY-F 47

Query: 514 DLQPSIELIERP 525
           +     ELIE+ 
Sbjct: 46  NNAVICELIEKS 11
>01074
          Length = 2584

 Score = 93.6 bits (231), Expect = 6e-19,   Method: Compositional matrix adjust.
 Identities = 61/150 (40%), Positives = 85/150 (56%)
 Frame = -2

Query: 1776 ERSTAQKNESARQQLERQNKELRSKLQEVEGAVKAKLKSTVAALEAKIAQLEEQVEQEAR 1835
            ERS +QK E+ R  LERQNKE+R KLQE+EG  +A+ K+T+     +  Q         +
Sbjct: 2583 ERSVSQKLENQRLALERQNKEMREKLQELEGQSRARTKATIGRTGGQDCQPGRTTGPGGQ 2404

Query: 1836 EKQAATKSXXXXXXXXXXXXXXXXXERKMAEQYKEQAEKGNTKVKQLKRQLEEAEEESQC 1895
               +                     ER+ A+QYKEQ +K N +VK LKRQ++EAEEE   
Sbjct: 2403 GASSPGSHEPQDGQASQRLQIQAEDERRSADQYKEQLDKMNNRVKALKRQVDEAEEECAR 2224

Query: 1896 INANRRKLQRELDEATESNEAMGREVNALK 1925
            INA +RK+QRELD+  E N+ + RE  +L+
Sbjct: 2223 INAQKRKVQRELDDQMEQNDVLVRETQSLR 2134
>01284
          Length = 1603

 Score = 87.0 bits (214), Expect = 6e-17,   Method: Compositional matrix adjust.
 Identities = 43/131 (32%), Positives = 72/131 (54%)
 Frame = +2

Query: 650 FRTVGQLYKEQLGKLMATLRNTTANFVRCIIPNHEKRSGKLDAFLVLEQLRCNGVLEGIR 709
           F +VG  +++QL  LM  L++T  NF+RCI PN +      +   +L QL+C G++  + 
Sbjct: 11  FISVGTKFRKQLLVLMDKLKSTGTNFIRCIKPNVKMVDHLFEGANILSQLQCAGMVSVLE 190

Query: 710 ICRQGFPNRIVFQEFRQRYEILAANAIPKGFMDGKQACILMIKALELDPNLYRIGQSKIF 769
           + +QGFP+R  F E    Y+      + +  +D +  C  + KAL LD   ++ G +K+F
Sbjct: 191 LMQQGFPSRTPFSELYNMYKKYLPPELSR--LDPRLFCKSLFKALGLDDKDFKFGLTKVF 364

Query: 770 FRTGVLAHLEE 780
           FR G  A  ++
Sbjct: 365 FRPGKFAEFDQ 397
>31878
          Length = 1178

 Score = 58.5 bits (140), Expect(2) = 3e-15,   Method: Compositional matrix adjust.
 Identities = 21/38 (55%), Positives = 28/38 (73%)
 Frame = -1

Query: 812  QLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTR 849
            Q  A++ IQRN   Y+K+R W WW+L+TKVKP+L V R
Sbjct: 1064 QHLAVRCIQRNVQKYMKIREWSWWKLYTKVKPILNVHR 951

 Score = 43.1 bits (100), Expect(2) = 3e-15,   Method: Composition-based stats.
 Identities = 18/31 (58%), Positives = 23/31 (74%)
 Frame = -2

Query: 774  VLAHLEEERDLKITDVIMAFQAMCRGYLARK 804
            VL+ LE  RD K+T ++  FQA+CRGYL RK
Sbjct: 1177 VLSQLEAGRDEKLTGIVTQFQALCRGYLGRK 1085
>20566
          Length = 911

 Score = 52.4 bits (124), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 50/178 (28%), Positives = 88/178 (49%)
 Frame = +3

Query: 1750 GNMEAMSDRVRKATLQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLQEVEGAVK 1809
            G +    DR +KA   A +L++EL  E+  + + E  R+ +E Q K+++ +L E E    
Sbjct: 12   GELRGAEDRSKKAMADAARLADELRQEQEHSMQVEKLRKGMEGQIKDMQVRLDEAEAQAL 191

Query: 1810 AKLKSTVAALEAKIAQLEEQVEQEAREKQAATKSXXXXXXXXXXXXXXXXXERKMAEQYK 1869
               K  +  LE ++ +LE +++ E R      K+                 +RK  E+ +
Sbjct: 192  KGGKKIIQKLEQRVRELEMELDGEQRRHAETQKNMRKADRRLKELAFQSDEDRKNQERIQ 371

Query: 1870 EQAEKGNTKVKQLKRQLEEAEEESQCINANRRKLQRELDEATESNEAMGREVNALKSK 1927
            +  +K   K+K  KRQ+EEAEE +    A  RK+Q EL++A E  +     ++ L++K
Sbjct: 372  DLVDKLQAKIKTYKRQVEEAEEIAAVNLAKFRKVQNELEDAEERADTAEGTLSKLRAK 545
>30605
          Length = 336

 Score = 35.0 bits (79), Expect = 0.28,   Method: Composition-based stats.
 Identities = 16/41 (39%), Positives = 29/41 (70%)
 Frame = -3

Query: 326 FQETLEAMSIMGFNEEEQLAILKVVSSVLQLGNIVFKKERN 366
           F+   EAM+ MG ++ +++AI  +V++VL LGNI F+ + +
Sbjct: 316 FKVCDEAMTRMGVSDADKMAIFMLVAAVLHLGNIAFEDDHD 194
>38905
          Length = 686

 Score = 30.8 bits (68), Expect = 6.3,   Method: Compositional matrix adjust.
 Identities = 32/108 (29%), Positives = 53/108 (49%)
 Frame = -3

Query: 1249 EVEHKKKKLEVQLQDLQSKCSDGERARAELSDKVHKLQNEVESVTGMLNEAEGKAIKLAK 1308
            EV+  K +L  Q   L+ +    ++ R +L++K  +LQ E ES T +  E   K  +LA+
Sbjct: 285  EVQLLKTQLAAQTVKLEQELKSSDQLRDQLAEKARQLQKESESDTDLQKELTQKDGQLAE 106

Query: 1309 DVASLGSXXXXXXXXXXXXXXXKLNVSTKLRQLEDERNSLQDQLDEEM 1356
            +  SL                    ++ K+RQLE++RN+   QL EE+
Sbjct: 105  ERQSLAQLQE--------------EMTEKMRQLEEQRNT-HAQLQEEL 7
>10536
          Length = 1110

 Score = 30.4 bits (67), Expect = 8.0,   Method: Compositional matrix adjust.
 Identities = 42/152 (27%), Positives = 77/152 (50%), Gaps = 9/152 (5%)
 Frame = -3

Query: 1142 RDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKH 1201
            ++L  E+E +K +LE   D     + L+ K+E+ +T       E+T   E+Q+ +M +KH
Sbjct: 1006 KELQNEMEDVKKQLEAVSDENKVFKRLQRKQERALTKF-----EDT---ESQLPQMLRKH 851

Query: 1202 TQAVEELTEQL----EQFKRAKANLDKSKQTLEKENADLA-----GELRVLGQAKQEVEH 1252
               V  L EQL    E+F R    L  ++  LEK  + +       E + LG+ + +++ 
Sbjct: 850  NNEVRALKEQLRHAREKFDRTDRYLHDAEDELEKATSQMKKYRALTEKKNLGE-RSDLDR 674

Query: 1253 KKKKLEVQLQDLQSKCSDGERARAELSDKVHK 1284
            +   +E+ L++  S+ ++ ER   EL  K H+
Sbjct: 673  RLNNVELTLEEKSSRIAELER-HVELVKKNHR 581
>19956
          Length = 536

 Score = 30.0 bits (66), Expect = 9.9,   Method: Compositional matrix adjust.
 Identities = 19/46 (41%), Positives = 29/46 (63%)
 Frame = -3

Query: 1246 AKQEVEHKKKKLEVQLQDLQSKCSDGERARAELSDKVHKLQNEVES 1291
            A+Q VE+    LEVQL DL +K +D + ARA L   +  L++++ S
Sbjct: 294  AEQRVEN----LEVQLADLSAKLNDADAARARLQKDMSGLRSQLSS 169
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|19526481|ref|NP_035595.2| spectrin alpha 1 [Mus
musculus]
         (2415 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

28965                                                                 105   3e-22
34010                                                                  71   4e-12
38533                                                                  68   5e-11
01375                                                                  65   2e-10
22703                                                                  56   2e-07
11641                                                                  50   8e-06
16716                                                                  47   6e-05
26578                                                                  47   7e-05
17567                                                                  45   3e-04
29243                                                                  41   0.005
13664                                                                  41   0.005
12324                                                                  40   0.008
17286                                                                  40   0.010
26032                                                                  36   0.18 
05206                                                                  35   0.32 
30740                                                                  33   1.1  
28095                                                                  32   3.0  
17613                                                                  32   3.4  
20131                                                                  31   5.1  
18822                                                                  30   9.8  
>28965
          Length = 421

 Score =  105 bits (261), Expect = 3e-22,   Method: Compositional matrix adjust.
 Identities = 55/138 (39%), Positives = 86/138 (62%)
 Frame = +2

Query: 202 QEELTARKGKVDRVNQYANECAQEKHPKLPEIKAKQDEVNAAWDRLWSLALKRRESLSNA 261
           Q++L   + KV  VN  A +   + HP+   I+ KQ+EVN AW RL  L+L R+E L  A
Sbjct: 2   QKDLQNHEDKVVEVNTLAEQLVTDGHPEEETIRQKQEEVNEAWKRLRQLSLLRQERLYGA 181

Query: 262 ADLQRFKRDVNEAIQWMEEKEPQLTSEDYGKDLVSSEALFHNHKRLERNLAVMDDKVKEL 321
            ++QRF RD +E I W++EK+  L+++DYG+DL S + L   H+ +ER+LA +++KV  L
Sbjct: 182 HEIQRFNRDADETIAWIQEKDAVLSTDDYGRDLASVQTLQRKHEGVERDLAALEEKVNAL 361

Query: 322 CAKADKLMISHSADAPQI 339
             ++ +L   H   + QI
Sbjct: 362 GTESVRLQGIHGDQSEQI 415

 Score = 84.0 bits (206), Expect = 7e-16,   Method: Compositional matrix adjust.
 Identities = 53/140 (37%), Positives = 84/140 (60%), Gaps = 3/140 (2%)
 Frame = +2

Query: 1122 QRDLKSNEPRLKDINKVADELLFEELLTPEGAHIRQ---ELNTRWNSLKRLADEQYQLLS 1178
            Q+DL+++E ++ ++N +A++L+ +    PE   IRQ   E+N  W  L++L+  + + L 
Sbjct: 2    QKDLQNHEDKVVEVNTLAEQLVTDG--HPEEETIRQKQEEVNEAWKRLRQLSLLRQERLY 175

Query: 1179 SAHAVEMFHREADDVKEQIDKKCRALNAADPGSDLLSVQALQRQHEVFERDIIPLGEKVT 1238
             AH ++ F+R+AD+    I +K   L+  D G DL SVQ LQR+HE  ERD+  L EKV 
Sbjct: 176  GAHEIQRFNRDADETIAWIQEKDAVLSTDDYGRDLASVQTLQRKHEGVERDLAALEEKVN 355

Query: 1239 TLGETAERLCESHPDATEDL 1258
             LG  + RL   H D +E +
Sbjct: 356  ALGTESVRLQGIHGDQSEQI 415

 Score = 72.8 bits (177), Expect = 1e-12,   Method: Compositional matrix adjust.
 Identities = 47/121 (38%), Positives = 75/121 (61%)
 Frame = +2

Query: 1658 EDPLKDLNDLAQELISSGTFNIDQIEEKMNGVNERFENVQSLAAAHHEKLKETYALFQFF 1717
            ED + ++N LA++L++ G    + I +K   VNE ++ ++ L+    E+L   + + +F 
Sbjct: 23   EDKVVEVNTLAEQLVTDGHPEEETIRQKQEEVNEAWKRLRQLSLLRQERLYGAHEIQRFN 202

Query: 1718 QDLDDEEAWIEEKLLRVSSQDYGRDLQSVQNLLKKHKRLEGELVAHEPAVQNVLDTAESL 1777
            +D D+  AWI+EK   +S+ DYGRDL SVQ L +KH+ +E +L A E  V N L T ES+
Sbjct: 203  RDADETIAWIQEKDAVLSTDDYGRDLASVQTLQRKHEGVERDLAALEEKV-NALGT-ESV 376

Query: 1778 R 1778
            R
Sbjct: 377  R 379

 Score = 63.5 bits (153), Expect = 9e-10,   Method: Compositional matrix adjust.
 Identities = 35/117 (29%), Positives = 67/117 (57%)
 Frame = +2

Query: 642 GQEMIEDGHYASEAVAARLSEVANLWKELLEATAQKGTQLYEANQLLQFENNAEDLKRWL 701
            ++++ DGH   E +  +  EV   WK L + +  +  +LY A+++ +F  +A++   W+
Sbjct: 53  AEQLVTDGHPEEETIRQKQEEVNEAWKRLRQLSLLRQERLYGAHEIQRFNRDADETIAWI 232

Query: 702 EEVEWQVTSEDYGKGLADVQNLLRKHGLLESDVTARQNQVDTLTDMAAHFEEIGHPD 758
           +E +  ++++DYG+ LA VQ L RKH  +E D+ A + +V+ L   +   + I H D
Sbjct: 233 QEKDAVLSTDDYGRDLASVQTLQRKHEGVERDLAALEEKVNALGTESVRLQGI-HGD 400

 Score = 58.5 bits (140), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 34/118 (28%), Positives = 61/118 (51%)
 Frame = +2

Query: 839 DIASHEPRIQVITERGNKMVEEGHFAAEDIASRVESLNKNMESLHARAIRRENDLKANVQ 898
           D+ +HE ++  +     ++V +GH   E I  + E +N+  + L   ++ R+  L    +
Sbjct: 8   DLQNHEDKVVEVNTLAEQLVTDGHPEEETIRQKQEEVNEAWKRLRQLSLLRQERLYGAHE 187

Query: 899 LQQYLADLHEAEAWIKEKEPIVDNKNYGADEEAAGALLKKHEAFLVDLNAFENSIKAL 956
           +Q++  D  E  AWI+EK+ ++   +YG D  +   L +KHE    DL A E  + AL
Sbjct: 188 IQRFNRDADETIAWIQEKDAVLSTDDYGRDLASVQTLQRKHEGVERDLAALEEKVNAL 361

 Score = 54.7 bits (130), Expect = 5e-07,   Method: Compositional matrix adjust.
 Identities = 30/104 (28%), Positives = 59/104 (56%)
 Frame = +2

Query: 308 ERNLAVMDDKVKELCAKADKLMISHSADAPQIQQMKLDLVSNWERIRALATNRYAKLKAS 367
           +++L   +DKV E+   A++L+     +   I+Q + ++   W+R+R L+  R  +L  +
Sbjct: 2   QKDLQNHEDKVVEVNTLAEQLVTDGHPEEETIRQKQEEVNEAWKRLRQLSLLRQERLYGA 181

Query: 368 YGYHRFLSDYDELSGWMKEKTALINADELPTDVASGEALLARHQ 411
           +   RF  D DE   W++EK A+++ D+   D+AS + L  +H+
Sbjct: 182 HEIQRFNRDADETIAWIQEKDAVLSTDDYGRDLASVQTLQRKHE 313

 Score = 52.4 bits (124), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 31/125 (24%), Positives = 61/125 (48%)
 Frame = +2

Query: 416 EIDSYDDRFQSADATGQELLDGNHEASEEIREKMTILANDWAALLELWDKCQHQYRQCLD 475
           ++ +++D+    +   ++L+   H   E IR+K   +   W  L +L    Q +     +
Sbjct: 8   DLQNHEDKVVEVNTLAEQLVTDGHPEEETIRQKQEEVNEAWKRLRQLSLLRQERLYGAHE 187

Query: 476 FHLFYRDSEQVDSWMSRQEAFLENEDLGNSVGSVEALLQKHDDFEEAFTAQEEKIITLDE 535
              F RD+++  +W+  ++A L  +D G  + SV+ L +KH+  E    A EEK+  L  
Sbjct: 188 IQRFNRDADETIAWIQEKDAVLSTDDYGRDLASVQTLQRKHEGVERDLAALEEKVNALGT 367

Query: 536 TATKL 540
            + +L
Sbjct: 368 ESVRL 382

 Score = 51.2 bits (121), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 39/133 (29%), Positives = 71/133 (53%), Gaps = 2/133 (1%)
 Frame = +2

Query: 1554 DGVINLGNSLIERRVCDG--DEENMQEQLDKLKENWDYLLERTTDKGQKLNEASRQQRFN 1611
            D V+ + N+L E+ V DG  +EE ++++ +++ E W  L + +  + ++L  A   QRFN
Sbjct: 26   DKVVEV-NTLAEQLVTDGHPEEETIRQKQEEVNEAWKRLRQLSLLRQERLYGAHEIQRFN 202

Query: 1612 TSIRDFEFWLSEAEGLLAMKDQARDLTSAGNLLKKHQLLEAEMLAREDPLKDLNDLAQEL 1671
                +   W+ E + +L+  D  RDL S   L +KH+ +E ++ A E+    +N L  E 
Sbjct: 203  RDADETIAWIQEKDAVLSTDDYGRDLASVQTLQRKHEGVERDLAALEEK---VNALGTES 373

Query: 1672 ISSGTFNIDQIEE 1684
            +     + DQ E+
Sbjct: 374  VRLQGIHGDQSEQ 412

 Score = 47.0 bits (110), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 28/120 (23%), Positives = 59/120 (49%)
 Frame = +2

Query: 731 ESDVTARQNQVDTLTDMAAHFEEIGHPDSGDIRARQESLLSRFEALKEPLAIRXXXXXXX 790
           + D+   +++V  +  +A      GHP+   IR +QE +   ++ L++   +R       
Sbjct: 2   QKDLQNHEDKVVEVNTLAEQLVTDGHPEEETIRQKQEEVNEAWKRLRQLSLLRQERLYGA 181

Query: 791 XXXXXXCRDSEDEEAWIQETEPSAASTHLGKDLVAAKNLLNRHEVILADIASHEPRIQVI 850
                  RD+++  AWIQE +   ++   G+DL + + L  +HE +  D+A+ E ++  +
Sbjct: 182 HEIQRFNRDADETIAWIQEKDAVLSTDDYGRDLASVQTLQRKHEGVERDLAALEEKVNAL 361

 Score = 46.6 bits (109), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 36/121 (29%), Positives = 62/121 (51%), Gaps = 1/121 (0%)
 Frame = +2

Query: 1235 EKVTTLGETAERLC-ESHPDATEDLQKQRTELNEAWDTLQGLTSDRKESLNEAHKFFLFL 1293
            +KV  +   AE+L  + HP+  E +++++ E+NEAW  L+ L+  R+E L  AH+   F 
Sbjct: 26   DKVVEVNTLAEQLVTDGHPEE-ETIRQKQEEVNEAWKRLRQLSLLRQERLYGAHEIQRFN 202

Query: 1294 SKASDLENWIKTIGGVISSPELAEDLTGTEILLERHQEHHDDIKREDPTFQALEDFGTEL 1353
              A +   WI+    V+S+ +   DL   + L  +H+    D+   +    AL   GTE 
Sbjct: 203  RDADETIAWIQEKDAVLSTDDYGRDLASVQTLQRKHEGVERDLAALEEKVNAL---GTES 373

Query: 1354 I 1354
            +
Sbjct: 374  V 376

 Score = 41.6 bits (96), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 31/116 (26%), Positives = 54/116 (46%)
 Frame = +2

Query: 1863 ENDFAVHKNRVQDVCAQGEDILNKEETQNKDKISTKIQVLNEKTXXXXXXXXXXXXQLDD 1922
            + D   H+++V +V    E ++     + ++ I  K + +NE              +L  
Sbjct: 2    QKDLQNHEDKVVEVNTLAEQLVTDGHPE-EETIRQKQEEVNEAWKRLRQLSLLRQERLYG 178

Query: 1923 VHAFQQFNWKADVVESWIGEKEASLKTKSNGADLTAFLTLLAKHDTLDASLQSFQQ 1978
             H  Q+FN  AD   +WI EK+A L T   G DL +  TL  KH+ ++  L + ++
Sbjct: 179  AHEIQRFNRDADETIAWIQEKDAVLSTDDYGRDLASVQTLQRKHEGVERDLAALEE 346

 Score = 41.6 bits (96), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 32/136 (23%), Positives = 66/136 (48%), Gaps = 1/136 (0%)
 Frame = +2

Query: 1439 KAITAQEGKISDLENVATRLIDNDHYAKEEIAARLQRVLDRWKALKEQLLTELGKLGDYA 1498
            K +   E K+ ++  +A +L+ + H  +E I  + + V + WK L++  L    +L    
Sbjct: 5    KDLQNHEDKVVEVNTLAEQLVTDGHPEEETIRQKQEEVNEAWKRLRQLSLLRQERLYGAH 184

Query: 1499 DLKQFYRDLEDLEEWINEMLPIACDESY-KDPTNIQRKYLKHQAFENEVNGRAEQVDGVI 1557
            ++++F RD ++   WI E   +   + Y +D  ++Q    KH+  E ++    E+V+   
Sbjct: 185  EIQRFNRDADETIAWIQEKDAVLSTDDYGRDLASVQTLQRKHEGVERDLAALEEKVNA-- 358

Query: 1558 NLGNSLIERRVCDGDE 1573
             LG   +  +   GD+
Sbjct: 359  -LGTESVRLQGIHGDQ 403

 Score = 34.3 bits (77), Expect = 0.62,   Method: Compositional matrix adjust.
 Identities = 29/112 (25%), Positives = 53/112 (47%), Gaps = 2/112 (1%)
 Frame = +2

Query: 1349 FGTELIDSGHRNRREIDNTLQNINSKRDNLEKSWENRKKMLDQCLELQLFRGKCDQVESW 1408
               +L+  GH     I    + +N     L +    R++ L    E+Q F    D+  +W
Sbjct: 50   LAEQLVTDGHPEEETIRQKQEEVNEAWKRLRQLSLLRQERLYGAHEIQRFNRDADETIAW 229

Query: 1409 MVARENSLRSDD--RDHLNSLQALMKKRDDLDKAITAQEGKISDLENVATRL 1458
            +  ++  L +DD  RD L S+Q L +K + +++ + A E K++ L   + RL
Sbjct: 230  IQEKDAVLSTDDYGRD-LASVQTLQRKHEGVERDLAALEEKVNALGTESVRL 382

 Score = 31.2 bits (69), Expect = 5.0,   Method: Compositional matrix adjust.
 Identities = 22/77 (28%), Positives = 38/77 (49%), Gaps = 2/77 (2%)
 Frame = +2

Query: 21  EEIQHRRAEVLNQYQRFKDRVAERGQKLEESYHYQVFRRDADDLEKWIMEKLEIAKDKTY 80
           E I+ ++ EV   ++R +     R ++L  ++  Q F RDAD+   WI EK  +     Y
Sbjct: 89  ETIRQKQEEVNEAWKRLRQLSLLRQERLYGAHEIQRFNRDADETIAWIQEKDAVLSTDDY 268

Query: 81  --EPTNIQGKYQKHESF 95
             +  ++Q   +KHE  
Sbjct: 269 GRDLASVQTLQRKHEGV 319
>34010
          Length = 832

 Score = 71.2 bits (173), Expect = 4e-12,   Method: Compositional matrix adjust.
 Identities = 43/140 (30%), Positives = 74/140 (52%)
 Frame = +3

Query: 397 PTDVASGEALLARHQQHKHEIDSYDDRFQSADATGQELLDGNHEASEEIREKMTILANDW 456
           P DV+  E L+  HQ  K EID+ ++ F      G++LL+  H   EE+REK+  L  + 
Sbjct: 87  PRDVSGVELLMNNHQSLKAEIDAREENFAICINLGRDLLNRKHYRQEEVREKLIQLTLER 266

Query: 457 AALLELWDKCQHQYRQCLDFHLFYRDSEQVDSWMSRQEAFLENEDLGNSVGSVEALLQKH 516
             + +LW       +  L+ + F RD+   ++W+  QE +  N+DLG+++ +VE L++  
Sbjct: 267 LDMTDLWKDRWEHLQLILEVYQFARDAAVAEAWLVAQEQYFLNQDLGDTLDAVENLIKSM 446

Query: 517 DDFEEAFTAQEEKIITLDET 536
              +    A+  KI  L +T
Sbjct: 447 KPLKSCCHAR-RKICCLRKT 503

 Score = 47.0 bits (110), Expect = 8e-05,   Method: Compositional matrix adjust.
 Identities = 33/128 (25%), Positives = 62/128 (48%), Gaps = 1/128 (0%)
 Frame = +3

Query: 1318 DLTGTEILLERHQEHHDDIKREDPTFQALEDFGTELIDSGHRNRREIDNTLQNINSKRDN 1377
            D++G E+L+  HQ    +I   +  F    + G +L++  H  + E+   L  +  +R +
Sbjct: 93   DVSGVELLMNNHQSLKAEIDAREENFAICINLGRDLLNRKHYRQEEVREKLIQLTLERLD 272

Query: 1378 LEKSWENRKKMLDQCLELQLFRGKCDQVESWMVARENS-LRSDDRDHLNSLQALMKKRDD 1436
            +   W++R + L   LE+  F       E+W+VA+E   L  D  D L++++ L+K    
Sbjct: 273  MTDLWKDRWEHLQLILEVYQFARDAAVAEAWLVAQEQYFLNQDLGDTLDAVENLIKSMKP 452

Query: 1437 LDKAITAQ 1444
            L     A+
Sbjct: 453  LKSCCHAR 476

 Score = 47.0 bits (110), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 34/126 (26%), Positives = 65/126 (51%)
 Frame = +3

Query: 1633 QARDLTSAGNLLKKHQLLEAEMLAREDPLKDLNDLAQELISSGTFNIDQIEEKMNGVNER 1692
            + RD++    L+  HQ L+AE+ ARE+      +L ++L++   +  +++ EK+  +   
Sbjct: 84   KPRDVSGVELLMNNHQSLKAEIDAREENFAICINLGRDLLNRKHYRQEEVREKLIQLTLE 263

Query: 1693 FENVQSLAAAHHEKLKETYALFQFFQDLDDEEAWIEEKLLRVSSQDYGRDLQSVQNLLKK 1752
              ++  L     E L+    ++QF +D    EAW+  +     +QD G  L +V+NL+K 
Sbjct: 264  RLDMTDLWKDRWEHLQLILEVYQFARDAAVAEAWLVAQEQYFLNQDLGDTLDAVENLIKS 443

Query: 1753 HKRLEG 1758
             K L+ 
Sbjct: 444  MKPLKS 461
>38533
          Length = 380

 Score = 67.8 bits (164), Expect = 5e-11,   Method: Compositional matrix adjust.
 Identities = 35/119 (29%), Positives = 62/119 (52%), Gaps = 1/119 (0%)
 Frame = +1

Query: 801 EDEEAWIQ-ETEPSAASTHLGKDLVAAKNLLNRHEVILADIASHEPRIQVITERGNKMVE 859
           EDE +W   + +P A ST LG  L A +NL+ +H+ + ++I +HEP I  +     +M+ 
Sbjct: 4   EDELSWYY*DRKPIAESTDLGNSLTAVQNLMKKHQALESEIVAHEPLIDAVATSAQQMIR 183

Query: 860 EGHFAAEDIASRVESLNKNMESLHARAIRRENDLKANVQLQQYLADLHEAEAWIKEKEP 918
             HFA  DI +R++ L    +      +  + +       Q++  +++E E W+ EK P
Sbjct: 184 TKHFATADIQTRLDDLTSPAQRSQVFYLL*KVETAGCFGAQKFYMEVNEVELWMNEKIP 360

 Score = 51.6 bits (122), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 25/57 (43%), Positives = 34/57 (59%)
 Frame = +1

Query: 1736 SQDYGRDLQSVQNLLKKHKRLEGELVAHEPAVQNVLDTAESLRDKAAVGKEEIQERL 1792
            S D G  L +VQNL+KKH+ LE E+VAHEP +  V  +A+ +         +IQ RL
Sbjct: 52   STDLGNSLTAVQNLMKKHQALESEIVAHEPLIDAVATSAQQMIRTKHFATADIQTRL 222

 Score = 45.4 bits (106), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 32/121 (26%), Positives = 55/121 (45%), Gaps = 1/121 (0%)
 Frame = +1

Query: 165 CEDILEWVK-EKEAIVTLVELGDDWERTEVLHKKFEEFQEELTARKGKVDRVNQYANECA 223
            ED L W   +++ I    +LG+     + L KK +  + E+ A +  +D V   A +  
Sbjct: 1   VEDELSWYY*DRKPIAESTDLGNSLTAVQNLMKKHQALESEIVAHEPLIDAVATSAQQMI 180

Query: 224 QEKHPKLPEIKAKQDEVNAAWDRLWSLALKRRESLSNAADLQRFKRDVNEAIQWMEEKEP 283
           + KH    +I+ + D++ +   R     L  +   +     Q+F  +VNE   WM EK P
Sbjct: 181 RTKHFATADIQTRLDDLTSPAQRSQVFYLL*KVETAGCFGAQKFYMEVNEVELWMNEKIP 360

Query: 284 Q 284
           Q
Sbjct: 361 Q 363

 Score = 45.1 bits (105), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 31/105 (29%), Positives = 54/105 (51%), Gaps = 3/105 (2%)
 Frame = +1

Query: 1418 SDDRDHLNSLQALMKKRDDLDKAITAQEGKISDLENVATRLIDNDHYAKEEIAARLQRVL 1477
            +D  + L ++Q LMKK   L+  I A E  I  +   A ++I   H+A  +I  RL  + 
Sbjct: 55   TDLGNSLTAVQNLMKKHQALESEIVAHEPLIDAVATSAQQMIRTKHFATADIQTRLDDLT 234

Query: 1478 DRWKALKEQLLTELGKL---GDYADLKQFYRDLEDLEEWINEMLP 1519
                A + Q+   L K+   G +   ++FY ++ ++E W+NE +P
Sbjct: 235  S--PAQRSQVFYLL*KVETAGCFGA-QKFYMEVNEVELWMNEKIP 360

 Score = 41.2 bits (95), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 22/62 (35%), Positives = 32/62 (51%)
 Frame = +1

Query: 710 SEDYGKGLADVQNLLRKHGLLESDVTARQNQVDTLTDMAAHFEEIGHPDSGDIRARQESL 769
           S D G  L  VQNL++KH  LES++ A +  +D +   A       H  + DI+ R + L
Sbjct: 52  STDLGNSLTAVQNLMKKHQALESEIVAHEPLIDAVATSAQQMIRTKHFATADIQTRLDDL 231

Query: 770 LS 771
            S
Sbjct: 232 TS 237

 Score = 40.0 bits (92), Expect = 0.011,   Method: Compositional matrix adjust.
 Identities = 25/100 (25%), Positives = 45/100 (45%)
 Frame = +1

Query: 1844 DSGDTLAATQSLLKKHEALENDFAVHKNRVQDVCAQGEDILNKEETQNKDKISTKIQVLN 1903
            D G++L A Q+L+KKH+ALE++   H+  +  V    + ++  +     D I T++  L 
Sbjct: 58   DLGNSLTAVQNLMKKHQALESEIVAHEPLIDAVATSAQQMIRTKHFATAD-IQTRLDDLT 234

Query: 1904 EKTXXXXXXXXXXXXQLDDVHAFQQFNWKADVVESWIGEK 1943
                           +       Q+F  + + VE W+ EK
Sbjct: 235  SPAQRSQVFYLL*KVETAGCFGAQKFYMEVNEVELWMNEK 354

 Score = 37.4 bits (85), Expect = 0.071,   Method: Compositional matrix adjust.
 Identities = 18/54 (33%), Positives = 31/54 (57%)
 Frame = +1

Query: 498 ENEDLGNSVGSVEALLQKHDDFEEAFTAQEEKIITLDETATKLIDNDHYDSENI 551
           E+ DLGNS+ +V+ L++KH   E    A E  I  +  +A ++I   H+ + +I
Sbjct: 49  ESTDLGNSLTAVQNLMKKHQALESEIVAHEPLIDAVATSAQQMIRTKHFATADI 210

 Score = 32.3 bits (72), Expect = 2.2,   Method: Compositional matrix adjust.
 Identities = 21/114 (18%), Positives = 54/114 (47%)
 Frame = +1

Query: 378 DELSGWMKEKTALINADELPTDVASGEALLARHQQHKHEIDSYDDRFQSADATGQELLDG 437
           DELS +  ++  +  + +L   + + + L+ +HQ  + EI +++    +   + Q+++  
Sbjct: 7   DELSWYY*DRKPIAESTDLGNSLTAVQNLMKKHQALESEIVAHEPLIDAVATSAQQMIRT 186

Query: 438 NHEASEEIREKMTILANDWAALLELWDKCQHQYRQCLDFHLFYRDSEQVDSWMS 491
            H A+ +I+ ++  L +        +   + +   C     FY +  +V+ WM+
Sbjct: 187 KHFATADIQTRLDDLTSPAQRSQVFYLL*KVETAGCFGAQKFYMEVNEVELWMN 348
>01375
          Length = 2323

 Score = 65.5 bits (158), Expect = 2e-10,   Method: Composition-based stats.
 Identities = 32/73 (43%), Positives = 46/73 (63%), Gaps = 1/73 (1%)
 Frame = +1

Query: 2344 SENIKTSDDIESAFQALAEG-KAYITKEDMKQALTPEQVSFCTIHMQQYMDPRGRSQPAG 2402
            +EN+++S ++E AF+AL  G K +IT +++   LT EQ  +C   MQ Y+D  GR+ P  
Sbjct: 4    TENVQSSSEVEQAFRALTSGEKPFITAQELYANLTKEQADYCIGRMQPYVDKTGRTIPDA 183

Query: 2403 YDYVGFTNSFFGN 2415
            YDYV FT   F N
Sbjct: 184  YDYVDFTRQLFVN 222
>22703
          Length = 906

 Score = 55.8 bits (133), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 32/112 (28%), Positives = 60/112 (53%)
 Frame = -3

Query: 422 DRFQSADATGQELLDGNHEASEEIREKMTILANDWAALLELWDKCQHQYRQCLDFHLFYR 481
           D+F+    TG+  +   H  S+EI EK+  L      L+   +  +  ++Q L+      
Sbjct: 877 DKFRK---TGRSFIANGHFLSKEIEEKIKQLDQSLEGLIRNLEHRRKLHQQNLEAQQLRH 707

Query: 482 DSEQVDSWMSRQEAFLENEDLGNSVGSVEALLQKHDDFEEAFTAQEEKIITL 533
           + EQ+++WM+ +E  L+ +  G S+   E +L++HD F +  TAQE+++  L
Sbjct: 706 EMEQIEAWMNLREPLLKEKKFGESIEGAEEMLRRHD*F*KTVTAQEDRVNAL 551

 Score = 53.9 bits (128), Expect = 8e-07,   Method: Compositional matrix adjust.
 Identities = 28/103 (27%), Positives = 57/103 (55%)
 Frame = -3

Query: 854 GNKMVEEGHFAAEDIASRVESLNKNMESLHARAIRRENDLKANVQLQQYLADLHEAEAWI 913
           G   +  GHF +++I  +++ L++++E L      R    + N++ QQ   ++ + EAW+
Sbjct: 859 GRSFIANGHFLSKEIEEKIKQLDQSLEGLIRNLEHRRKLHQQNLEAQQLRHEMEQIEAWM 680

Query: 914 KEKEPIVDNKNYGADEEAAGALLKKHEAFLVDLNAFENSIKAL 956
             +EP++  K +G   E A  +L++H+ F   + A E+ + AL
Sbjct: 679 NLREPLLKEKKFGESIEGAEEMLRRHD*F*KTVTAQEDRVNAL 551

 Score = 48.9 bits (115), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 30/112 (26%), Positives = 60/112 (53%), Gaps = 1/112 (0%)
 Frame = -3

Query: 1342 TFQALEDFGTELIDSGHRNRREIDNTLQNINSKRDNLEKSWENRKKMLDQCLELQLFRGK 1401
             F      G   I +GH   +EI+  ++ ++   + L ++ E+R+K+  Q LE Q  R +
Sbjct: 883  PFDKFRKTGRSFIANGHFLSKEIEEKIKQLDQSLEGLIRNLEHRRKLHQQNLEAQQLRHE 704

Query: 1402 CDQVESWMVARENSLRSDD-RDHLNSLQALMKKRDDLDKAITAQEGKISDLE 1452
             +Q+E+WM  RE  L+     + +   + ++++ D   K +TAQE +++ L+
Sbjct: 703  MEQIEAWMNLREPLLKEKKFGESIEGAEEMLRRHD*F*KTVTAQEDRVNALQ 548

 Score = 38.1 bits (87), Expect = 0.046,   Method: Compositional matrix adjust.
 Identities = 23/111 (20%), Positives = 57/111 (51%), Gaps = 1/111 (0%)
 Frame = -3

Query: 635 LNNLEKTGQEMIEDGHYASEAVAARLSEVANLWKELLEATAQKGTQLYEAN-QLLQFENN 693
            +   KTG+  I +GH+ S+ +  ++ ++    + L+     +  +L++ N +  Q  + 
Sbjct: 880 FDKFRKTGRSFIANGHFLSKEIEEKIKQLDQSLEGLIRNLEHR-RKLHQQNLEAQQLRHE 704

Query: 694 AEDLKRWLEEVEWQVTSEDYGKGLADVQNLLRKHGLLESDVTARQNQVDTL 744
            E ++ W+   E  +  + +G+ +   + +LR+H      VTA++++V+ L
Sbjct: 703 MEQIEAWMNLREPLLKEKKFGESIEGAEEMLRRHD*F*KTVTAQEDRVNAL 551
>11641
          Length = 2509

 Score = 50.4 bits (119), Expect = 8e-06,   Method: Composition-based stats.
 Identities = 28/79 (35%), Positives = 44/79 (55%), Gaps = 7/79 (8%)
 Frame = -1

Query: 961  EVCQQQQAAPV---DEAGREARVIALYDFEARSRREVSMKKNDVLTLLSSI----NKDWW 1013
            +V Q   A PV   + A +     A + F+ARS  EV++    V+ +L+      N +WW
Sbjct: 895  QVSQPDPAQPVSSAEPASQHEYYCADFPFQARSSNEVTLFAGQVVVVLNRQDLDGNTEWW 716

Query: 1014 KVEADDHQGFVPAVYVRKL 1032
             V+AD +QG+ PA Y+RK+
Sbjct: 715  LVDADGYQGYAPASYLRKM 659
>16716
          Length = 934

 Score = 47.4 bits (111), Expect = 6e-05,   Method: Compositional matrix adjust.
 Identities = 23/70 (32%), Positives = 37/70 (52%), Gaps = 1/70 (1%)
 Frame = -1

Query: 961  EVCQQQQAAPV-DEAGREARVIALYDFEARSRREVSMKKNDVLTLLSSINKDWWKVEADD 1019
            E+  ++ AAP   + G  +  IALYD++A    E++   +DV+T +  I+  WW+     
Sbjct: 523  EMADEEPAAPAQSQPGGGSTAIALYDYQAADDDELTFDPDDVITDIEMIDDGWWRGSCHG 344

Query: 1020 HQGFVPAVYV 1029
              G  PA YV
Sbjct: 343  KNGLFPANYV 314
>26578
          Length = 430

 Score = 47.4 bits (111), Expect = 7e-05,   Method: Compositional matrix adjust.
 Identities = 32/131 (24%), Positives = 61/131 (46%), Gaps = 1/131 (0%)
 Frame = +1

Query: 147 EKSDVLLRALKFYQYSQECEDILEWVKEKEAIVTLVELGDDWERTEVLHKKFEEFQEEL- 205
           E+   L    K Y   +E  D+L+W+ EK  +    + G D+E   +L ++F+EF  +  
Sbjct: 1   ERRGKLEEVFKLYTLHREIYDLLQWIAEKSLVAGSNDPGQDYEHVSMLKEQFKEFARDTE 180

Query: 206 TARKGKVDRVNQYANECAQEKHPKLPEIKAKQDEVNAAWDRLWSLALKRRESLSNAADLQ 265
           +  + +V   N+  ++     H     I   +D VN AW  L  L   R + L ++ +L 
Sbjct: 181 SMGQERVASANEICDQLIALDHSDSASIAEWKDNVNEAWADLLELIDTRTQLLQSSWELH 360

Query: 266 RFKRDVNEAIQ 276
           +F  +  + ++
Sbjct: 361 KFLYECKDTLE 393

 Score = 45.1 bits (105), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 32/114 (28%), Positives = 52/114 (45%), Gaps = 1/114 (0%)
 Frame = +1

Query: 1186 FHREADDVKEQIDKKCRALNAADPGSDLLSVQALQRQHEVFERDIIPLG-EKVTTLGETA 1244
             HRE  D+ + I +K     + DPG D   V  L+ Q + F RD   +G E+V +  E  
Sbjct: 43   LHREIYDLLQWIAEKSLVAGSNDPGQDYEHVSMLKEQFKEFARDTESMGQERVASANEIC 222

Query: 1245 ERLCESHPDATEDLQKQRTELNEAWDTLQGLTSDRKESLNEAHKFFLFLSKASD 1298
            ++L       +  + + +  +NEAW  L  L   R + L  + +   FL +  D
Sbjct: 223  DQLIALDHSDSASIAEWKDNVNEAWADLLELIDTRTQLLQSSWELHKFLYECKD 384

 Score = 39.3 bits (90), Expect = 0.021,   Method: Compositional matrix adjust.
 Identities = 32/125 (25%), Positives = 53/125 (42%), Gaps = 4/125 (3%)
 Frame = +1

Query: 254 RRESLSNAADLQRFKRDVNEAIQWMEEKEPQLTSEDYGKDLVSSEALFHNHKRLERNLAV 313
           RR  L     L    R++ + +QW+ EK     S D G+D      L    K   R+   
Sbjct: 4   RRGKLEEVFKLYTLHREIYDLLQWIAEKSLVAGSNDPGQDYEHVSMLKEQFKEFARDTES 183

Query: 314 MDDK----VKELCAKADKLMISHSADAPQIQQMKLDLVSNWERIRALATNRYAKLKASYG 369
           M  +      E+C   D+L+    +D+  I + K ++   W  +  L   R   L++S+ 
Sbjct: 184 MGQERVASANEIC---DQLIALDHSDSASIAEWKDNVNEAWADLLELIDTRTQLLQSSWE 354

Query: 370 YHRFL 374
            H+FL
Sbjct: 355 LHKFL 369

 Score = 34.7 bits (78), Expect = 0.42,   Method: Compositional matrix adjust.
 Identities = 24/80 (30%), Positives = 35/80 (43%)
 Frame = +1

Query: 1939 WIGEKEASLKTKSNGADLTAFLTLLAKHDTLDASLQSFQQERLSEIAELKDQLVAGEHSQ 1998
            WI EK     +   G D      L  +        +S  QER++   E+ DQL+A +HS 
Sbjct: 73   WIAEKSLVAGSNDPGQDYEHVSMLKEQFKEFARDTESMGQERVASANEICDQLIALDHSD 252

Query: 1999 AKAIEEQHAALLRHWEQLLE 2018
            + +I E    +   W  LLE
Sbjct: 253  SASIAEWKDNVNEAWADLLE 312

 Score = 32.0 bits (71), Expect = 3.0,   Method: Compositional matrix adjust.
 Identities = 35/126 (27%), Positives = 57/126 (45%), Gaps = 8/126 (6%)
 Frame = +1

Query: 1706 KLKETYALFQFFQDLDDEEAWIEEKLLRVSSQDYGRDLQSVQNLLKKHKRL--EGELVAH 1763
            KL+E + L+   +++ D   WI EK L   S D G+D + V  L ++ K    + E +  
Sbjct: 13   KLEEVFKLYTLHREIYDLLQWIAEKSLVAGSNDPGQDYEHVSMLKEQFKEFARDTESMGQ 192

Query: 1764 E--PAVQNVLDTAESL--RDKAAVG--KEEIQERLAQFVQHWEKLKELAKTRGVNLEESL 1817
            E   +   + D   +L   D A++   K+ + E        W  L EL  TR   L+ S 
Sbjct: 193  ERVASANEICDQLIALDHSDSASIAEWKDNVNEA-------WADLLELIDTRTQLLQSSW 351

Query: 1818 EYLQFM 1823
            E  +F+
Sbjct: 352  ELHKFL 369
>17567
          Length = 448

 Score = 45.4 bits (106), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 29/122 (23%), Positives = 62/122 (50%)
 Frame = -3

Query: 1621 LSEAEGLLAMKDQARDLTSAGNLLKKHQLLEAEMLAREDPLKDLNDLAQELISSGTFNID 1680
            L E +  +  +D  + L +  ++L++H L EA++ A    ++ LN  +Q           
Sbjct: 350  LKEVQSKVVGEDYGKHLQATQDMLEQHSLQEAQLQALTRRVRKLNRKSQ------GAQEQ 189

Query: 1681 QIEEKMNGVNERFENVQSLAAAHHEKLKETYALFQFFQDLDDEEAWIEEKLLRVSSQDYG 1740
             +++++  +N +  NVQ+ +    + L+     +QF QD ++E+ W+ E++  V S   G
Sbjct: 188  SLDKRLEALNAQLNNVQAQSDKRRQGLETAQQYYQFLQDTEEEDRWVGERIDAVRSPSLG 9

Query: 1741 RD 1742
            +D
Sbjct: 8    KD 3

 Score = 44.7 bits (104), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 42/160 (26%), Positives = 67/160 (41%), Gaps = 7/160 (4%)
 Frame = -3

Query: 670 LLEATAQKGTQLYEANQLLQFENNAEDLKRWLEEVEWQVTSEDYGKGLADVQNLLRKHGL 729
           LL     + + L   N L+      E ++  L+EV+ +V  EDYGK L   Q++L +H L
Sbjct: 443 LLAKLESRKSTLSGYNNLMAMFREIESIQEELKEVQSKVVGEDYGKHLQATQDMLEQHSL 264

Query: 730 LESDVTARQNQVDTLTDMAAHFEEIGHPDSGDIRARQESLLSRFEALKEPLA-------I 782
            E+ + A          +     ++     G   A+++SL  R EAL   L         
Sbjct: 263 QEAQLQA----------LTRRVRKLNRKSQG---AQEQSLDKRLEALNAQLNNVQAQSDK 123

Query: 783 RXXXXXXXXXXXXXCRDSEDEEAWIQETEPSAASTHLGKD 822
           R              +D+E+E+ W+ E   +  S  LGKD
Sbjct: 122 RRQGLETAQQYYQFLQDTEEEDRWVGERIDAVRSPSLGKD 3

 Score = 38.9 bits (89), Expect = 0.025,   Method: Compositional matrix adjust.
 Identities = 29/128 (22%), Positives = 59/128 (46%)
 Frame = -3

Query: 1713 LFQFFQDLDDEEAWIEEKLLRVSSQDYGRDLQSVQNLLKKHKRLEGELVAHEPAVQNVLD 1772
            L   F++++  +  ++E   +V  +DYG+ LQ+ Q++L++H   E +L A    V+ +  
Sbjct: 392  LMAMFREIESIQEELKEVQSKVVGEDYGKHLQATQDMLEQHSLQEAQLQALTRRVRKLN- 216

Query: 1773 TAESLRDKAAVGKEEIQERLAQFVQHWEKLKELAKTRGVNLEESLEYLQFMXXXXXXXXW 1832
                 R      ++ + +RL         ++  +  R   LE + +Y QF+        W
Sbjct: 215  -----RKSQGAQEQSLDKRLEALNAQLNNVQAQSDKRRQGLETAQQYYQFLQDTEEEDRW 51

Query: 1833 LGEKCALV 1840
            +GE+   V
Sbjct: 50   VGERIDAV 27

 Score = 35.0 bits (79), Expect = 0.33,   Method: Compositional matrix adjust.
 Identities = 39/133 (29%), Positives = 63/133 (47%), Gaps = 3/133 (2%)
 Frame = -3

Query: 164 ECEDILEWVKEKEAIVTLVELGDDWERTEVL---HKKFEEFQEELTARKGKVDRVNQYAN 220
           E E I E +KE ++ V   + G   + T+ +   H   E   + LT R  K++R +Q A 
Sbjct: 374 EIESIQEELKEVQSKVVGEDYGKHLQATQDMLEQHSLQEAQLQALTRRVRKLNRKSQGAQ 195

Query: 221 ECAQEKHPKLPEIKAKQDEVNAAWDRLWSLALKRRESLSNAADLQRFKRDVNEAIQWMEE 280
           E + +K  +L  + A+ + V A  D       KRR+ L  A    +F +D  E  +W+ E
Sbjct: 194 EQSLDK--RLEALNAQLNNVQAQSD-------KRRQGLETAQQYYQFLQDTEEEDRWVGE 42

Query: 281 KEPQLTSEDYGKD 293
           +   + S   GKD
Sbjct: 41  RIDAVRSPSLGKD 3
>29243
          Length = 1147

 Score = 41.2 bits (95), Expect = 0.005,   Method: Composition-based stats.
 Identities = 22/53 (41%), Positives = 31/53 (58%), Gaps = 4/53 (7%)
 Frame = +2

Query: 981  IALYDFEARSRREVSMKKNDVLTLLSSINKD--WWKVEADDHQ--GFVPAVYV 1029
            +A+YD+ A S  ++SMK ND + +LS   +D  WWK E    Q  G+ P  YV
Sbjct: 641  VAVYDYAATSTSQLSMKLNDRIAILSKNGQDKGWWKGENLRTQKIGYFPLAYV 799
>13664
          Length = 507

 Score = 41.2 bits (95), Expect = 0.005,   Method: Composition-based stats.
 Identities = 19/56 (33%), Positives = 33/56 (58%), Gaps = 1/56 (1%)
 Frame = +2

Query: 969  APVDEAGREARVIALYDFEARSRREVSMKKNDVLTLLSSINKDWWKVE-ADDHQGF 1023
            +P+    +  +V+ALYD++A+   E+++   DV+ LL   ++ WW  E  D  QGF
Sbjct: 338  SPLGSTRKPKKVVALYDYKAQRSDELTILSGDVIMLLHKDSESWWMGELLDGQQGF 505
>12324
          Length = 946

 Score = 40.4 bits (93), Expect = 0.008,   Method: Composition-based stats.
 Identities = 16/51 (31%), Positives = 29/51 (56%)
 Frame = +3

Query: 979  RVIALYDFEARSRREVSMKKNDVLTLLSSINKDWWKVEADDHQGFVPAVYV 1029
            +V+A+YD+EA    E++  +N V+ ++   +  WW+   D   G  P+ YV
Sbjct: 693  KVVAIYDYEAEKDDELTFSENSVIYVIRKNDDGWWEGVMDGVTGLFPSNYV 845
>17286
          Length = 489

 Score = 40.4 bits (93), Expect = 0.010,   Method: Composition-based stats.
 Identities = 16/53 (30%), Positives = 31/53 (58%)
 Frame = +3

Query: 982  ALYDFEARSRREVSMKKNDVLTLLSSINKDWWKVEADDHQGFVPAVYVRKLAP 1034
            A+YDF   S  E+  ++ D++TL+S ++++W++       G+ P  YV  + P
Sbjct: 36   AIYDFLPESDGELGFQEGDMITLISQVDENWFEGSVHGKVGYFPINYVEVVVP 194
>26032
          Length = 465

 Score = 36.2 bits (82), Expect = 0.18,   Method: Compositional matrix adjust.
 Identities = 17/48 (35%), Positives = 28/48 (58%)
 Frame = +2

Query: 985  DFEARSRREVSMKKNDVLTLLSSINKDWWKVEADDHQGFVPAVYVRKL 1032
            DFE     E+  +KND++TL+S  ++  W  E +  +G+ PA +V  L
Sbjct: 29   DFERHDDDELGFRKNDIITLISQKDEHCWIGELNGLRGWFPAKFVEVL 172
>05206
          Length = 1075

 Score = 35.0 bits (79), Expect = 0.32,   Method: Composition-based stats.
 Identities = 20/51 (39%), Positives = 29/51 (56%), Gaps = 2/51 (3%)
 Frame = +1

Query: 982  ALYDFEARSRREVSMKKNDVLTLLSSINKDWWK--VEADDHQGFVPAVYVR 1030
            ALY FEA +   V M +N+ + +L     D W    +AD  +GFVP+ YV+
Sbjct: 103  ALYPFEAMNEGSVPMGENEEMQILEEDQGDGWTRVRKADGSEGFVPSSYVQ 255
>30740
          Length = 488

 Score = 33.5 bits (75), Expect = 1.1,   Method: Composition-based stats.
 Identities = 18/51 (35%), Positives = 27/51 (52%)
 Frame = +2

Query: 974  AGREARVIALYDFEARSRREVSMKKNDVLTLLSSINKDWWKVEADDHQGFV 1024
            A RE +++  YDF  R   ++   K D+L L+S   ++WW   A D  G V
Sbjct: 176  APRE-KLMGKYDFSGRDPEDLPFSKGDILELISKDEEEWWT--ARDKHGRV 319
>28095
          Length = 597

 Score = 32.0 bits (71), Expect = 3.0,   Method: Composition-based stats.
 Identities = 21/74 (28%), Positives = 31/74 (41%), Gaps = 13/74 (17%)
 Frame = +3

Query: 982  ALYDFEARSRREVSMKKNDVLTLLSSINKDWW--KVEADDHQGFVPAVYVRK-------- 1031
            A+YD++A    EVS    D +     ++  W   +VE     G +P+ YV +        
Sbjct: 270  AMYDYQAADSDEVSFNDGDTIIECQPVDAGWMTGRVERTGQYGMLPSNYVERIN*TSLFS 449

Query: 1032 ---LAPDELPGFPQ 1042
               LAP    GF Q
Sbjct: 450  LCLLAPPRKVGFLQ 491
>17613
          Length = 1108

 Score = 32.0 bits (71), Expect = 3.4,   Method: Compositional matrix adjust.
 Identities = 18/55 (32%), Positives = 31/55 (56%), Gaps = 2/55 (3%)
 Frame = +2

Query: 1396 QLFRGKCDQVESWMVARENSLRSDD--RDHLNSLQALMKKRDDLDKAITAQEGKI 1448
            Q FR KC+  E W   +E+ L+S D  +  LN L+A+ KK +  +  + A + ++
Sbjct: 938  QKFRHKCEIHEEWSQGKEDMLQSRDFKQCRLNELKAMKKKHEAFESDLAAHQDRV 1102

 Score = 31.6 bits (70), Expect = 4.5,   Method: Compositional matrix adjust.
 Identities = 18/51 (35%), Positives = 27/51 (52%), Gaps = 1/51 (1%)
 Frame = +2

Query: 2044 FAHKASAFNNWCENAEEDL-SEPVHCVSLNEIRQLQKEHEAFLASLAGAQE 2093
            F HK      W +  E+ L S       LNE++ ++K+HEAF + LA  Q+
Sbjct: 944  FRHKCEIHEEWSQGKEDMLQSRDFKQCRLNELKAMKKKHEAFESDLAAHQD 1096
>20131
          Length = 574

 Score = 31.2 bits (69), Expect = 5.1,   Method: Composition-based stats.
 Identities = 12/52 (23%), Positives = 30/52 (57%)
 Frame = -2

Query: 981  IALYDFEARSRREVSMKKNDVLTLLSSINKDWWKVEADDHQGFVPAVYVRKL 1032
            +A+Y + +    +++  + D++ L++  ++DWW     +  G  P+ YV+K+
Sbjct: 471  VAMYSYVSGETADLTFNEGDMI-LVTKKDEDWWTGTLGEKTGMFPSTYVKKV 319
>18822
          Length = 474

 Score = 30.4 bits (67), Expect = 9.8,   Method: Compositional matrix adjust.
 Identities = 35/124 (28%), Positives = 64/124 (51%), Gaps = 10/124 (8%)
 Frame = -2

Query: 840 IASHEPRIQVITERGNKMVEEGHFAAEDIAS-RVESLNKNMESLHARAIRREND-----L 893
           IA  E   +V T+    +V++   +++D+ +  +E+LN   E++    +RRE       L
Sbjct: 401 IAQVESDFKVTTKTAQSLVQD---SSQDVVTVMLETLNTQKEAI--VKLRREIPERIKYL 237

Query: 894 KA---NVQ-LQQYLADLHEAEAWIKEKEPIVDNKNYGADEEAAGALLKKHEAFLVDLNAF 949
           KA   NV+ L+  + DL   EAW+   E ++ +    +  EAA A L++H+ F  +   +
Sbjct: 236 KAVLPNVESLETGVLDL---EAWLSSGEELLGSHKLDSTAEAAEARLERHKGFFAE-TTY 69

Query: 950 ENSI 953
           + SI
Sbjct: 68  QKSI 57
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|116089347|ref|NP_031406.2| spectrin SH3 domain
binding protein 1 isoform 3 [Mus musculus]
         (475 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

12324                                                                 102   4e-22
16716                                                                  61   1e-09
17286                                                                  54   1e-07
01494                                                                  54   1e-07
29687                                                                  51   1e-06
20131                                                                  50   1e-06
13664                                                                  41   0.001
11228                                                                  41   0.001
28095                                                                  41   0.001
26032                                                                  39   0.005
31183                                                                  37   0.012
15115                                                                  35   0.065
19469                                                                  34   0.099
29243                                                                  34   0.10 
38574                                                                  34   0.15 
>12324
          Length = 946

 Score =  102 bits (253), Expect = 4e-22,   Method: Compositional matrix adjust.
 Identities = 48/78 (61%), Positives = 56/78 (71%), Gaps = 6/78 (7%)
 Frame = +3

Query: 400 DPYADGDPA------WAPKNYIEKVVAIYDYTKDKDDELSFKEGAIIYVIKKNDDGWFEG 453
           DPYA   P       + P  YIEKVVAIYDY  +KDDEL+F E ++IYVI+KNDDGW+EG
Sbjct: 624 DPYAATGPGFLGPDEYMPATYIEKVVAIYDYEAEKDDELTFSENSVIYVIRKNDDGWWEG 803

Query: 454 VCNRVTGLFPGNYVESIM 471
           V + VTGLFP NYVE  M
Sbjct: 804 VMDGVTGLFPSNYVEPCM 857
>16716
          Length = 934

 Score = 60.8 bits (146), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 25/51 (49%), Positives = 32/51 (62%)
 Frame = -1

Query: 418 VVAIYDYTKDKDDELSFKEGAIIYVIKKNDDGWFEGVCNRVTGLFPGNYVE 468
            +A+YDY    DDEL+F    +I  I+  DDGW+ G C+   GLFP NYVE
Sbjct: 463 AIALYDYQAADDDELTFDPDDVITDIEMIDDGWWRGSCHGKNGLFPANYVE 311
>17286
          Length = 489

 Score = 54.3 bits (129), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 24/52 (46%), Positives = 34/52 (65%)
 Frame = +3

Query: 420 AIYDYTKDKDDELSFKEGAIIYVIKKNDDGWFEGVCNRVTGLFPGNYVESIM 471
           AIYD+  + D EL F+EG +I +I + D+ WFEG  +   G FP NYVE ++
Sbjct: 36  AIYDFLPESDGELGFQEGDMITLISQVDENWFEGSVHGKVGYFPINYVEVVV 191
>01494
          Length = 2122

 Score = 54.3 bits (129), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 25/60 (41%), Positives = 38/60 (63%), Gaps = 1/60 (1%)
 Frame = +3

Query: 417 KVVAIYDYTKDKDDELSFKEGAIIYVIKKNDDGWFEG-VCNRVTGLFPGNYVESIMHYTD 475
           +V A++DY  ++DDELSF +GAII  + + D GW+ G    +    FP N+VE I  ++D
Sbjct: 309 RVKALHDYNANRDDELSFCKGAIITNVSRQDGGWWRGDYGAKKQHWFPSNFVEEIETHSD 488
>29687
          Length = 434

 Score = 50.8 bits (120), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 26/60 (43%), Positives = 36/60 (60%), Gaps = 1/60 (1%)
 Frame = -2

Query: 417 KVVAIYDYTKDKDDELSFKEGAIIYVIKKNDDGWFEG-VCNRVTGLFPGNYVESIMHYTD 475
           +V A++DY   ++DELSF +GAII  + + D GW+ G    +    FP NYVE I   TD
Sbjct: 295 RVKALHDYNAKREDELSFCKGAIITNVSRQDGGWWRGDYGTKKQHWFPSNYVEEIDTQTD 116
>20131
          Length = 574

 Score = 50.4 bits (119), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 22/55 (40%), Positives = 33/55 (60%)
 Frame = -2

Query: 416 EKVVAIYDYTKDKDDELSFKEGAIIYVIKKNDDGWFEGVCNRVTGLFPGNYVESI 470
           E  VA+Y Y   +  +L+F EG +I V KK++D W+ G     TG+FP  YV+ +
Sbjct: 480 EYYVAMYSYVSGETADLTFNEGDMILVTKKDED-WWTGTLGEKTGMFPSTYVKKV 319
>13664
          Length = 507

 Score = 41.2 bits (95), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 15/38 (39%), Positives = 25/38 (65%)
 Frame = +2

Query: 416 EKVVAIYDYTKDKDDELSFKEGAIIYVIKKNDDGWFEG 453
           +KVVA+YDY   + DEL+   G +I ++ K+ + W+ G
Sbjct: 365 KKVVALYDYKAQRSDELTILSGDVIMLLHKDSESWWMG 478
>11228
          Length = 2155

 Score = 41.2 bits (95), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 22/57 (38%), Positives = 32/57 (56%), Gaps = 3/57 (5%)
 Frame = -2

Query: 417  KVVAIYDYTKDKD-DELSFKEGAIIYVIKKNDDGWFEGVCNRV--TGLFPGNYVESI 470
            +VVA+  Y K  D DELSF +G +  V  + +DGW    C R   +GL P  +V+ +
Sbjct: 1668 RVVAMLSYRKATDSDELSFCKGDVFVVQNEMEDGWLWVTCERTKESGLVPAPFVKDL 1498
>28095
          Length = 597

 Score = 40.8 bits (94), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 22/53 (41%), Positives = 27/53 (50%), Gaps = 2/53 (3%)
 Frame = +3

Query: 420 AIYDYTKDKDDELSFKEGAIIYVIKKNDDGWFEGVCNRVT--GLFPGNYVESI 470
           A+YDY     DE+SF +G  I   +  D GW  G   R    G+ P NYVE I
Sbjct: 270 AMYDYQAADSDEVSFNDGDTIIECQPVDAGWMTGRVERTGQYGMLPSNYVERI 428
>26032
          Length = 465

 Score = 38.9 bits (89), Expect = 0.005,   Method: Composition-based stats.
 Identities = 17/46 (36%), Positives = 27/46 (58%)
 Frame = +2

Query: 423 DYTKDKDDELSFKEGAIIYVIKKNDDGWFEGVCNRVTGLFPGNYVE 468
           D+ +  DDEL F++  II +I + D+  + G  N + G FP  +VE
Sbjct: 29  DFERHDDDELGFRKNDIITLISQKDEHCWIGELNGLRGWFPAKFVE 166
>31183
          Length = 923

 Score = 37.4 bits (85), Expect = 0.012,   Method: Compositional matrix adjust.
 Identities = 16/30 (53%), Positives = 20/30 (66%)
 Frame = +1

Query: 439 IIYVIKKNDDGWFEGVCNRVTGLFPGNYVE 468
           +I  I+  DDGW+ G C+   GLFP NYVE
Sbjct: 7   VITDIEMIDDGWWRGSCHGKNGLFPANYVE 96
>15115
          Length = 443

 Score = 35.0 bits (79), Expect = 0.065,   Method: Composition-based stats.
 Identities = 17/41 (41%), Positives = 25/41 (60%), Gaps = 1/41 (2%)
 Frame = -2

Query: 429 DDELSFKEGAIIYVIKKNDDGWFEGVC-NRVTGLFPGNYVE 468
           D E++F    II  I + D+GW++G   +   G+FP NYVE
Sbjct: 418 DTEITFDPDDIITNIDQIDEGWWQGFAPDGSYGMFPANYVE 296
>19469
          Length = 428

 Score = 34.3 bits (77), Expect = 0.099,   Method: Compositional matrix adjust.
 Identities = 16/49 (32%), Positives = 28/49 (57%), Gaps = 3/49 (6%)
 Frame = -1

Query: 420 AIYDYTKDKDDELSFKEGAIIYVIKKND---DGWFEGVCNRVTGLFPGN 465
           A+YD   +  DEL+F+ G +I +++++    DGW+        G+ PGN
Sbjct: 353 ALYDNIAETPDELAFRRGDVITILEQDTAGLDGWWLCSLRGRQGIAPGN 207
>29243
          Length = 1147

 Score = 34.3 bits (77), Expect = 0.10,   Method: Compositional matrix adjust.
 Identities = 21/54 (38%), Positives = 28/54 (51%), Gaps = 4/54 (7%)
 Frame = +2

Query: 419 VAIYDYTKDKDDELSFKEGAIIYVIKKN--DDGWFEGVCNRV--TGLFPGNYVE 468
           VA+YDY      +LS K    I ++ KN  D GW++G   R    G FP  YV+
Sbjct: 641 VAVYDYAATSTSQLSMKLNDRIAILSKNGQDKGWWKGENLRTQKIGYFPLAYVD 802
>38574
          Length = 408

 Score = 33.9 bits (76), Expect = 0.15,   Method: Composition-based stats.
 Identities = 16/36 (44%), Positives = 24/36 (66%), Gaps = 2/36 (5%)
 Frame = -1

Query: 435 KEGAIIYVIKKNDDGWFEGVCNRV--TGLFPGNYVE 468
           + G   +V K+ +DGW++G   R   TGLFPG++VE
Sbjct: 303 RNGRHSHVHKRREDGWYKGTQERTSKTGLFPGSFVE 196
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|39204499|ref|NP_035040.1| neurofilament, light
polypeptide [Mus musculus]
         (543 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

11243                                                                 102   4e-22
02016                                                                  65   5e-11
22014                                                                  51   1e-06
16684                                                                  29   6.1  
>11243
          Length = 828

 Score =  102 bits (254), Expect = 4e-22,   Method: Compositional matrix adjust.
 Identities = 66/194 (34%), Positives = 110/194 (56%), Gaps = 2/194 (1%)
 Frame = -2

Query: 213 IDSLMDEIAFLKKVHXXXXXXXXXXXXXXXXSVEMDVSSKP--DLSAALKDIRAQYEKLA 270
           I+SL +E+ +LKK H                +V++ V S P  DL+  + D+R+QYE + 
Sbjct: 752 IESLKEELIYLKKNHEEELAVVRSSARG---NVDVQVDSAPPVDLAQIMXDVRSQYESMM 582

Query: 271 AKNMQNAEEWFKSRFTVLTESAAKNTDAVRAAKDEVSESRRLLKAKTLEIEACRGMNEAL 330
            KN Q  E  +K +   L    A NT A++ +K  +++ +R +++  +E+++   M  AL
Sbjct: 581 EKNRQELEACYKGQSENLNHEVATNTAALQTSKTAITDLKRTIQSLEIELQSLLSMKGAL 402

Query: 331 EKQLQELEDKQNADISAMQDTINKLENELRSTKSEMARYLKEYQDLLNVKMALDIEIAAY 390
           E  L E E +  A ++ +Q  I ++E EL++ +S+      EY+ LL+ K  L++EIA Y
Sbjct: 401 EGTLAETEAQYGAQLNHLQAMITQVEMELQNLRSDADHQSLEYKRLLDAKTRLEMEIATY 222

Query: 391 RKLLEGEETRLSFT 404
           R+LLEGE+TR S T
Sbjct: 221 RRLLEGEDTRFSQT 180
>02016
          Length = 3061

 Score = 65.5 bits (158), Expect = 5e-11,   Method: Compositional matrix adjust.
 Identities = 75/287 (26%), Positives = 131/287 (45%), Gaps = 2/287 (0%)
 Frame = +3

Query: 143 IRDLRLAAEDATNEKQALQGEREGLEETLRNLQARYEEEVLSREDAEGRLMXXXXXXXXX 202
           + D  + +++   E  AL+ E  GLE+ L  L+ + EEE L R D E RL          
Sbjct: 66  LNDAEVPSQETGKENAALRAEVAGLEKQLAKLKKQLEEETLLRVDLENRLQ--------- 218

Query: 203 XXXXXXXXXXIDSLMDEIAFLKKVHXXXXXXXXXXXXXXXXSVE--MDVSSKPDLSAALK 260
                       SL +EI F  +V+                 V+  ++   +  L  AL+
Sbjct: 219 ------------SLKEEINFKSQVYEQELEESRVRTTVEIEQVDGRLEHEYEQRLLEALR 362

Query: 261 DIRAQYEKLAAKNMQNAEEWFKSRFTVLTESAAKNTDAVRAAKDEVSESRRLLKAKTLEI 320
           +IRAQ+E          E  ++++   L   A ++  A  +A +E+  +R+       E+
Sbjct: 363 EIRAQHESDLQTVRVELETLYENKIADLKAQANRSNSASGSAWEELRITRKRADDLGAEL 542

Query: 321 EACRGMNEALEKQLQELEDKQNADISAMQDTINKLENELRSTKSEMARYLKEYQDLLNVK 380
              +      E ++ +LE +   +    +  + + ++EL   +  +   ++EY DLL++K
Sbjct: 543 AKLKAETAGFELRISDLESQLAREREEFRLRLAQKDDELAELRLTLEEQMQEYSDLLDIK 722

Query: 381 MALDIEIAAYRKLLEGEETRLSFTSVGSITSGYSQSSQVFGRSAYSG 427
           + LD EI AYRKLLE EE+RL+ +   S +   SQ+S+   R+  SG
Sbjct: 723 IRLDREIDAYRKLLESEESRLNISLDASQS---SQTSRSPARATPSG 854
>22014
          Length = 353

 Score = 50.8 bits (120), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 24/54 (44%), Positives = 37/54 (68%)
 Frame = -1

Query: 352 INKLENELRSTKSEMARYLKEYQDLLNVKMALDIEIAAYRKLLEGEETRLSFTS 405
           +N+L+ E+   ++EM   L E Q L++ K++L++EIAAYRKLLE EE+R     
Sbjct: 212 VNQLKEEMNKLRAEMEAMLVELQTLMDAKLSLELEIAAYRKLLETEESRTGLPP 51
>16684
          Length = 1773

 Score = 28.9 bits (63), Expect = 6.1,   Method: Compositional matrix adjust.
 Identities = 18/56 (32%), Positives = 30/56 (53%)
 Frame = +2

Query: 98  NDRFASFIERVHELEQQNKVLEAELLVLRQKHSEPSRFRALYEQEIRDLRLAAEDA 153
           N R    I++ HELE  NK L+ ++ +L+++ +  +R R  Y+Q    LR     A
Sbjct: 635 NCRSKRMIQK-HELESTNKTLQQQISMLKRQLTVMTRERDFYKQRCEMLRTGVARA 799
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|42741690|ref|NP_075719.1| ubiquitin-conjugating
enzyme E2 variant 1 [Mus musculus]
         (147 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

20166                                                                  99   5e-22
02313                                                                  43   4e-05
37111                                                                  42   8e-05
21443                                                                  37   0.003
39424                                                                  35   0.009
04905                                                                  35   0.010
02740                                                                  35   0.014
31099                                                                  34   0.025
38163                                                                  32   0.074
12485                                                                  32   0.084
14380                                                                  32   0.096
18592                                                                  30   0.26 
05633                                                                  29   0.84 
19311                                                                  28   1.6  
26740                                                                  27   2.2  
>20166
          Length = 446

 Score = 99.4 bits (246), Expect = 5e-22,   Method: Compositional matrix adjust.
 Identities = 51/116 (43%), Positives = 67/116 (57%)
 Frame = +1

Query: 30  DGTVSWGLEDDEDMTLTRWTGMIIGPPRTIYENRIYSLKIECGPKYPEAPPSVRFVTRXX 89
           DGT+SWGL  D+D  L  W G IIGP +T YE RIY+L++ C   YP  PPSVRF T+  
Sbjct: 1   DGTISWGLVRDDDRNLESWQGTIIGPMKTPYEGRIYTLRMSCPMSYPRHPPSVRFETKIN 180

Query: 90  XXXXXXXXXXXDPRATAVLAKWQNSHSIKVILQELRRLMMSKENMKLPQPPEGQCY 145
                        R     A W ++ ++KVIL+E+R  M SK+N KL QP +G  +
Sbjct: 181 LSCVEDNGTVDLKRLGRKFA-WDSNTTLKVILEEIRNCMASKDNAKLQQPNDGSFF 345
>02313
          Length = 891

 Score = 43.1 bits (100), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 18/46 (39%), Positives = 26/46 (56%)
 Frame = -1

Query: 42  DMTLTRWTGMIIGPPRTIYENRIYSLKIECGPKYPEAPPSVRFVTR 87
           D  +  W   I GPP T+YE   +   ++    YP +PPSVRF+T+
Sbjct: 687 DDNIFEWEVAIFGPPGTLYEGGYFKAHMKFPADYPYSPPSVRFITK 550
>37111
          Length = 611

 Score = 42.4 bits (98), Expect = 8e-05,   Method: Compositional matrix adjust.
 Identities = 32/118 (27%), Positives = 49/118 (41%), Gaps = 9/118 (7%)
 Frame = -1

Query: 39  DDEDMTLTRWTGMIIGPPRTIYENRIYSLKIECGPKYPEAPPSVRFVTRXXXXXXXXXXX 98
           D  D  LT   G I+GPP T YE   + L I     YP  PP V+F+T+           
Sbjct: 416 DFVDGMLTHLKGEIMGPPETPYEGGRFELDIRIPETYPFNPPLVKFLTKIWH-------- 261

Query: 99  XXDPRATAVLA---------KWQNSHSIKVILQELRRLMMSKENMKLPQPPEGQCYSN 147
              P  ++V           +W  + +++ +L  L+ LM + E    P  P+    +N
Sbjct: 260 ---PNVSSVTGAICLDILKDQWAAAMTLRTVLLSLQALMAAAE----PDDPQDAVVAN 108
>21443
          Length = 610

 Score = 37.0 bits (84), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 19/47 (40%), Positives = 24/47 (51%)
 Frame = -1

Query: 41  EDMTLTRWTGMIIGPPRTIYENRIYSLKIECGPKYPEAPPSVRFVTR 87
           EDM   +W   I+GP  + YE  ++ L I     YP  PP V F TR
Sbjct: 454 EDMF--QWQATIMGPRDSAYEGGVFFLTISFPTDYPFKPPKVSFTTR 320
>39424
          Length = 1749

 Score = 35.4 bits (80), Expect = 0.009,   Method: Compositional matrix adjust.
 Identities = 21/64 (32%), Positives = 34/64 (53%)
 Frame = -1

Query: 17   LLEELEEGQKGVGDGTVSWGLEDDEDMTLTRWTGMIIGPPRTIYENRIYSLKIECGPKYP 76
            L ++L E  K   +G  S GL DD+D+   +W  +I GPP T+++   +   +    +YP
Sbjct: 1671 LRKQLAELSKSGTEG-FSAGLIDDDDVY--KWEVLIYGPPETLFDGGYFKAHLIFPKEYP 1501

Query: 77   EAPP 80
              PP
Sbjct: 1500 NRPP 1489
>04905
          Length = 1868

 Score = 35.4 bits (80), Expect = 0.010,   Method: Compositional matrix adjust.
 Identities = 14/43 (32%), Positives = 24/43 (55%)
 Frame = -1

Query: 45   LTRWTGMIIGPPRTIYENRIYSLKIECGPKYPEAPPSVRFVTR 87
            L  +T    GPP T YE  ++ ++++   +YP   PS+ F+ R
Sbjct: 1691 LNEFTVKFFGPPSTPYEGGVWKVRVDLPERYPFKSPSIGFINR 1563
>02740
          Length = 2287

 Score = 34.7 bits (78), Expect = 0.014,   Method: Compositional matrix adjust.
 Identities = 18/42 (42%), Positives = 21/42 (50%)
 Frame = -1

Query: 45   LTRWTGMIIGPPRTIYENRIYSLKIECGPKYPEAPPSVRFVT 86
            L +W G I G   T+YE   Y L +E    YP    SVRF T
Sbjct: 1918 LFKWVGTIEGAKGTVYEGLQYKLVLEFPSGYPYQAVSVRFST 1793
>31099
          Length = 748

 Score = 33.9 bits (76), Expect = 0.025,   Method: Compositional matrix adjust.
 Identities = 14/43 (32%), Positives = 21/43 (48%)
 Frame = +2

Query: 45  LTRWTGMIIGPPRTIYENRIYSLKIECGPKYPEAPPSVRFVTR 87
              W   I+GP ++ Y+  ++ L I     YP  PP V F T+
Sbjct: 179 FFHWQATIMGPNKSPYQGGVFFLTITFPADYPFKPPKVAFTTK 307
>38163
          Length = 2214

 Score = 32.3 bits (72), Expect = 0.074,   Method: Compositional matrix adjust.
 Identities = 21/70 (30%), Positives = 34/70 (48%), Gaps = 1/70 (1%)
 Frame = -3

Query: 16   RLLEELEEGQKGVGDGTVSWGLED-DEDMTLTRWTGMIIGPPRTIYENRIYSLKIECGPK 74
            RL EE +  +K    G V+   ++ D  + L  W   I G   T++E  ++SL++     
Sbjct: 1765 RLAEERKSWRKDHPFGFVAKPTKNPDGTLNLFNWECKIPGKKGTMWEGGLFSLRMLFKED 1586

Query: 75   YPEAPPSVRF 84
            YP  PP  +F
Sbjct: 1585 YPSTPPKCKF 1556
>12485
          Length = 652

 Score = 32.3 bits (72), Expect = 0.084,   Method: Compositional matrix adjust.
 Identities = 14/43 (32%), Positives = 23/43 (53%)
 Frame = +1

Query: 45 LTRWTGMIIGPPRTIYENRIYSLKIECGPKYPEAPPSVRFVTR 87
          L  +     GPP T YE  ++ ++++   KYP   PS+ F+ R
Sbjct: 4  LNEFLVKFYGPPSTPYEGGVWKVRVDLPEKYPFKSPSIGFMNR 132
>14380
          Length = 1522

 Score = 32.0 bits (71), Expect = 0.096,   Method: Compositional matrix adjust.
 Identities = 24/84 (28%), Positives = 35/84 (41%)
 Frame = +3

Query: 4   TTGSGVKVPRNFRLLEELEEGQKGVGDGTVSWGLEDDEDMTLTRWTGMIIGPPRTIYENR 63
           TT     V R+   L E   G K            +DED+T  + T  I GP  T Y   
Sbjct: 108 TTSYSSSVERDIFPLPECARGNKI---------FTNDEDITDIQAT--IEGPAGTPYAGG 254

Query: 64  IYSLKIECGPKYPEAPPSVRFVTR 87
           ++ +K+     +P  PP   F+T+
Sbjct: 255 LFRMKLVLSKSFPSEPPKAFFITK 326
>18592
          Length = 475

 Score = 30.4 bits (67), Expect = 0.26,   Method: Compositional matrix adjust.
 Identities = 19/81 (23%), Positives = 39/81 (48%)
 Frame = +2

Query: 7   SGVKVPRNFRLLEELEEGQKGVGDGTVSWGLEDDEDMTLTRWTGMIIGPPRTIYENRIYS 66
           S  K+    RL +EL++ +K       ++ ++D ++  +  W  +++ P    Y    ++
Sbjct: 74  SFTKMAATRRLTKELQDIRKEASQK--AFRIKDQDESNILHW-EVVLVPENPPYNKGTFT 244

Query: 67  LKIECGPKYPEAPPSVRFVTR 87
           + I    +YP  PP V F T+
Sbjct: 245 VDINFPAEYPFKPPKVTFKTK 307
>05633
          Length = 1150

 Score = 28.9 bits (63), Expect = 0.84,   Method: Compositional matrix adjust.
 Identities = 14/41 (34%), Positives = 19/41 (46%)
 Frame = +3

Query: 45 LTRWTGMIIGPPRTIYENRIYSLKIECGPKYPEAPPSVRFV 85
          L  W   + G   T+YE   + L  + G KYP   P V F+
Sbjct: 36 LNEWIVDLEGATGTLYEGEKFQLHFKFGAKYPFDSPQVTFL 158
>19311
          Length = 1071

 Score = 27.7 bits (60), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 16/54 (29%), Positives = 24/54 (44%), Gaps = 7/54 (12%)
 Frame = -2

Query: 41  EDMTLTRWTGMII-------GPPRTIYENRIYSLKIECGPKYPEAPPSVRFVTR 87
           E +  T WTG +        GP     +   + L ++    YP  PP VRF+T+
Sbjct: 545 EGIQATHWTGTVATGRPPSQGPRAVRXKGGWFLLYLQIPHSYPMRPPKVRFITK 384
>26740
          Length = 404

 Score = 27.3 bits (59), Expect = 2.2,   Method: Compositional matrix adjust.
 Identities = 13/43 (30%), Positives = 21/43 (48%)
 Frame = +2

Query: 39  DDEDMTLTRWTGMIIGPPRTIYENRIYSLKIECGPKYPEAPPS 81
           DDE + + +   +I GP  T Y N  +   +     YP +PP+
Sbjct: 272 DDERLDIMKV--LITGPSDTPYANGAFEFDVYFPQDYPNSPPT 394
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|112807168|ref|NP_001036800.1| echinoderm microtubule
associated protein like 1 isoform 1 [Mus musculus]
         (814 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

18461                                                                 102   6e-22
27525                                                                  75   1e-13
12574                                                                  43   6e-04
00561                                                                  38   0.014
13335                                                                  38   0.018
03387                                                                  38   0.019
20662                                                                  37   0.041
15780                                                                  36   0.061
15972                                                                  35   0.099
29912                                                                  35   0.11 
19498                                                                  35   0.15 
13278                                                                  34   0.19 
02090                                                                  34   0.21 
14500                                                                  33   0.48 
25930                                                                  33   0.59 
34005                                                                  33   0.59 
19949                                                                  32   0.75 
37142                                                                  32   0.91 
02147                                                                  32   1.4  
00825                                                                  31   1.9  
01598                                                                  30   4.4  
10264                                                                  30   5.5  
03044                                                                  29   6.9  
02948                                                                  29   7.8  
17266                                                                  29   8.2  
17598                                                                  29   8.3  
>18461
          Length = 456

 Score =  102 bits (254), Expect = 6e-22,   Method: Compositional matrix adjust.
 Identities = 59/148 (39%), Positives = 85/148 (57%), Gaps = 2/148 (1%)
 Frame = +1

Query: 598 VAVGTLTGRWFVFDTETKDLVTVHTDGNEQLSVMRYSPD-GNFLAIGSHDNCIYIYGVTD 656
           +AVG   G + V ++ET + +       E++S +++SPD G +LA+ SHDN + +Y V  
Sbjct: 7   LAVGLKDGSFVVLNSETLEEIAGFHHRKEEISDIKFSPDVGKYLAVASHDNFVDLYSVA- 183

Query: 657 NGRKYTRVGKCSGHSSFITHLDWSVNSQFLVSNSGDYEILYWVPSACKQVVSVET-TRDI 715
            G K  RVG C G SS+ITH+DW    + L+ NSG  E L++     K++    T     
Sbjct: 184 -GVK--RVGTCKGASSYITHIDWDTRGKVLMVNSGAKEQLFFEAPRGKRITLRNTEIEKF 354

Query: 716 EWATYTCTLGFHVFGVWPEGSDGTDINA 743
            WA++TC LG    GVWP  SD TD+NA
Sbjct: 355 NWASWTCVLGVTCEGVWPAKSDVTDVNA 438
>27525
          Length = 828

 Score = 74.7 bits (182), Expect = 1e-13,   Method: Compositional matrix adjust.
 Identities = 40/120 (33%), Positives = 73/120 (60%), Gaps = 3/120 (2%)
 Frame = +2

Query: 624 GNEQLSVMRYSPDGNFLAIGSHDNCIYIYGVTDNGRKY-TRVGKCSGHSSFITHLDWSVN 682
           G  Q++ + +SPDG+ LA+G HD  +++Y V ++G  +  +      +S+FI HLDWS +
Sbjct: 65  GQAQINAISFSPDGSQLAVGCHDGFVHVYVVHEDGLVFRQKSAALRYNSTFIMHLDWSSD 244

Query: 683 SQFLVSNSGDYEILYW-VPSACKQVVSVETTRDIEWATYTCTLGF-HVFGVWPEGSDGTD 740
            ++L    GDYE+++W V +  KQ  S    RD+ W+T++  +G+   + +  +G+ G+D
Sbjct: 245 CRYLQCTLGDYELVFWEVQNMKKQ--SGRALRDVNWSTFSSPVGYPPCWALADDGARGSD 418

 Score = 56.2 bits (134), Expect = 5e-08,   Method: Compositional matrix adjust.
 Identities = 25/87 (28%), Positives = 45/87 (51%)
 Frame = +3

Query: 728 VFGVWPEGSDGTDINAVCRAHERKLLCTGDDFGKVHLFSYPCSQFRAPSHIYSGHSSHVT 787
           + G W     G  IN  CR+     + TGD  G++ LF YP +  +        +SS+ T
Sbjct: 378 LVGPWQMMERGEVINMACRSKYLDFILTGDSRGRIRLFKYPSTGSKVECQETKPYSSNTT 557

Query: 788 NVDFLCEDSHLISTGGKDTSIMQWRVI 814
             + L +DS ++ +GG+D ++M + ++
Sbjct: 558 AAEILSDDSGILVSGGRDAALMYFALV 638
>12574
          Length = 521

 Score = 42.7 bits (99), Expect = 6e-04,   Method: Composition-based stats.
 Identities = 24/71 (33%), Positives = 39/71 (54%)
 Frame = +3

Query: 628 LSVMRYSPDGNFLAIGSHDNCIYIYGVTDNGRKYTRVGKCSGHSSFITHLDWSVNSQFLV 687
           LS +++SP+G++LA  S D  I I+G  D   + T     +GH   ++ + WS +S+ L 
Sbjct: 195 LSAVKFSPNGDWLASSSADKLIKIWGAYDGKFEKT----IAGHKLGLSDVAWSSDSKLLC 362

Query: 688 SNSGDYEILYW 698
           S S D  +  W
Sbjct: 363 SASDDKTLKIW 395
>00561
          Length = 1003

 Score = 38.1 bits (87), Expect = 0.014,   Method: Compositional matrix adjust.
 Identities = 34/150 (22%), Positives = 60/150 (40%), Gaps = 3/150 (2%)
 Frame = -3

Query: 343 AVDDSNDHVLSVWDWQKEERLADVKCSNEAVFAADFHPTDTNIIVTCGKSHLYFWTLEGN 402
           A+  S D  L +WD    +     +   + V +  F   +  I+       +  W    N
Sbjct: 821 ALSGSWDQTLRLWDLAAGKTTRRFEGHTKDVLSVAFSADNRQIVSGSRDKTIKLW----N 654

Query: 403 SLNKKQGLFEKQEKPKFVLCVTFSENGDTITGDSSG---NILVWGKGTNRISYAVQGAHE 459
           +L + +   ++     +V CV FS N       S G    + VW     ++     G H 
Sbjct: 653 TLAECKFTIQEDGHTDWVSCVRFSPNHSNPIIVSCGWDRTVKVWNLANCKLKNNHHG-HN 477

Query: 460 GGIFALCMLRDGTLVSGGGKDRRLISWNGN 489
           G +  + +  DG+L + GGKD + + W+ N
Sbjct: 476 GYLNTVTVSPDGSLCTSGGKDSKALLWDLN 387

 Score = 35.0 bits (79), Expect = 0.12,   Method: Compositional matrix adjust.
 Identities = 55/241 (22%), Positives = 87/241 (36%), Gaps = 18/241 (7%)
 Frame = -3

Query: 469 RDGTLVSGGGKDRRLISW------NGNYQKLHKAEIPEQFGPIRTVAEGKGNVILIGT-T 521
           +D   +    +D+ LI W      + NY    K            V    GN  L G+  
Sbjct: 980 KDPDTIISASRDKTLIVWKLTRDEDTNYGYPQKRLYGHSHFISDVVLSSDGNYALSGSWD 801

Query: 522 RNFVLQGTLSGDFTPITQGHTDELWGLAIHASKPQFLTCGHDKHATLWDAVGHRPVWDKI 581
           +   L    +G  T   +GHT ++  +A  A   Q ++   DK   LW+ +        I
Sbjct: 800 QTLRLWDLAAGKTTRRFEGHTKDVLSVAFSADNRQIVSGSRDKTIKLWNTLAECKF--TI 627

Query: 582 IED-------PAQSSGFHPSGSVVAVGTLTGRW----FVFDTETKDLVTVHTDGNEQLSV 630
            ED         + S  H +  +V+ G     W     V++     L   H   N  L+ 
Sbjct: 626 QEDGHTDWVSCVRFSPNHSNPIIVSCG-----WDRTVKVWNLANCKLKNNHHGHNGYLNT 462

Query: 631 MRYSPDGNFLAIGSHDNCIYIYGVTDNGRKYTRVGKCSGHSSFITHLDWSVNSQFLVSNS 690
           +  SPDG+    G  D+   ++ + D    YT       H+  I  L +S N  +L    
Sbjct: 461 VTVSPDGSLCTSGGKDSKALLWDLNDGKNLYTL-----EHNDIINALCFSPNRYWLCVAY 297

Query: 691 G 691
           G
Sbjct: 296 G 294
>13335
          Length = 863

 Score = 37.7 bits (86), Expect = 0.018,   Method: Compositional matrix adjust.
 Identities = 47/213 (22%), Positives = 85/213 (39%), Gaps = 22/213 (10%)
 Frame = +1

Query: 253 VVLYNVEEQ-LQRHYAGHNDDVKCLAVHPDRITIATGQVAGTSKDGKQLPPHVRIWDSVT 311
           + ++ V  Q L R Y GH D V  LA  P+   + +G   G           + +WD+  
Sbjct: 133 ICMWEVATQKLVRSYVGHEDSVMALAYSPNGHYLVSGSPNGD----------LYVWDASF 282

Query: 312 LNTLHV-IGIGFFDRAVTCIAFSKSNGGGHLCAVDDS----------NDHVLSVWDWQKE 360
            +  H+ + +   D  VTC  FS + G    CA + S           D+++ +W +  +
Sbjct: 283 GHCRHLTLRVDAHDLGVTCCEFSPTFGTA--CAENSSTCNLLLATGGKDNLIKLWTFSAQ 456

Query: 361 ERLADV--KCSN------EAVFAADFHPTDTNIIVTCGKSHLYFW-TLEGNSLNKKQGLF 411
               +V  +C +      + V A  F P+   +        +  W +++G +L   +   
Sbjct: 457 VGSPEVTLQCRDILSGHSDLVMACAFSPSSALLASGSFDKSVRLWDSVKGVALFSIEAC- 633

Query: 412 EKQEKPKFVLCVTFSENGDTITGDSSGNIL-VW 443
                 +FV C  FS +G  +   S   I+ +W
Sbjct: 634 ----HSRFVTCCAFSIDGTLLASGSMDRIIKIW 720

 Score = 35.4 bits (80), Expect = 0.095,   Method: Compositional matrix adjust.
 Identities = 49/196 (25%), Positives = 78/196 (39%), Gaps = 9/196 (4%)
 Frame = +1

Query: 625 NEQLSVMRYSPDGNFLAIGSHDNCIYIYGVTDNGRKYTRVGKCSGHSSFITHLDWSVNSQ 684
              + V ++SP  + L  GS D+ I ++ V       + VG    H   +  L +S N  
Sbjct: 61  KSSIRVCKFSPSSSHLVSGSDDDTICMWEVATQKLVRSYVG----HEDSVMALAYSPNGH 228

Query: 685 FLVSNSGDYEILYWVPS--ACKQVVSVETTRDIEWATYTCTLGFHVFG-VWPEGSDGTDI 741
           +LVS S + ++  W  S   C+ +       D+     TC      FG    E S   ++
Sbjct: 229 YLVSGSPNGDLYVWDASFGHCRHLTLRVDAHDLG---VTCCEFSPTFGTACAENSSTCNL 399

Query: 742 NAVCRAHERKLLCTGDDFGKVHLFSYPCSQFRAPS------HIYSGHSSHVTNVDFLCED 795
                     LL TG     + L+++  +Q  +P        I SGHS  V    F    
Sbjct: 400 ----------LLATGGKDNLIKLWTFS-AQVGSPEVTLQCRDILSGHSDLVMACAF-SPS 543

Query: 796 SHLISTGGKDTSIMQW 811
           S L+++G  D S+  W
Sbjct: 544 SALLASGSFDKSVRLW 591
>03387
          Length = 1891

 Score = 37.7 bits (86), Expect = 0.019,   Method: Compositional matrix adjust.
 Identities = 39/176 (22%), Positives = 73/176 (41%), Gaps = 11/176 (6%)
 Frame = +1

Query: 336 NGGGHLCAVDDSNDHVLSVWDW---QKEERLADVKC----SNEAVFAADFHPTDTNIIVT 388
           N  GHL +  D  DH + +WD    Q+E R+ D           V    +H    ++  +
Sbjct: 394 NLNGHLLSASD--DHTICLWDINSTQRESRVVDAHTIFTGHTSVVEDVAWHLLHESLFGS 567

Query: 389 CGKSH-LYFWTLEGNSLNKKQGLFEKQEKPKFVLCVTFSENGDTI--TGDSSGNILVWGK 445
                 L  W    N+ +K   + +       V C++F+   + I  TG +   + +W  
Sbjct: 568 VADDQKLMIWDTRSNTTSKPSHVVDAHTAE--VNCLSFNPYSEFILATGSADKTVALWDL 741

Query: 446 GTNRISYAVQGAHEGGIFAL-CMLRDGTLVSGGGKDRRLISWNGNYQKLHKAEIPE 500
              ++      +H+  IF +     + T+++  G DRRL  W  +  K+ + ++PE
Sbjct: 742 RNLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLHVW--DLSKIGEEQLPE 903
>20662
          Length = 1220

 Score = 36.6 bits (83), Expect = 0.041,   Method: Compositional matrix adjust.
 Identities = 19/57 (33%), Positives = 28/57 (49%), Gaps = 1/57 (1%)
 Frame = +2

Query: 539 QGHTDELWGLAIHASKPQ-FLTCGHDKHATLWDAVGHRPVWDKIIEDPAQSSGFHPS 594
           + H+D +W +  H ++P  FL+C  D    LWD    +P        P  SSGF P+
Sbjct: 500 RAHSDIVWDVQCHPTEPALFLSCSQDGKIVLWDVRESKPA----TCLPKCSSGFKPT 658
>15780
          Length = 735

 Score = 36.2 bits (82), Expect = 0.061,   Method: Compositional matrix adjust.
 Identities = 23/89 (25%), Positives = 43/89 (48%), Gaps = 1/89 (1%)
 Frame = -1

Query: 433 TGDSSGNILVWGKGTNRISYAVQGAHEGGIFALCMLRDGTLVSGGGKDRRLISWNGNYQK 492
           T  +   ++VW   +   + A   AH   ++ALC  RDGT+++ GG D  +  W  +  +
Sbjct: 723 TAGADHTVIVWDIASGT-AVAHLTAHTDTVYALCFSRDGTVLASGGMDNSIRLW--DLAR 553

Query: 493 LHKAEIPEQFGPIRTVAEGKGN-VILIGT 520
           + + + PE    + +      N  +L+GT
Sbjct: 552 VMEEQDPETDSNVPSSLSVNTNPALLLGT 466
>15972
          Length = 1069

 Score = 35.4 bits (80), Expect = 0.099,   Method: Compositional matrix adjust.
 Identities = 30/126 (23%), Positives = 53/126 (42%), Gaps = 7/126 (5%)
 Frame = +3

Query: 540 GHTDELWGLAIHASKPQFLTCGHDKHATLWDAVGHRPVWDKIIEDPAQSSGFHPSGSVVA 599
           GH   +  LA+H S    LT   D+   LW+ +  R  +   +++ A+S  + P G    
Sbjct: 231 GHKGPVRHLAVHPSGKLTLTVSQDRTLRLWNNMNGRIAFISNMKEAAESVRWAPGGLYYV 410

Query: 600 VGTLTGRWFVFDTETKDLV-------TVHTDGNEQLSVMRYSPDGNFLAIGSHDNCIYIY 652
           V        V+  E+K L+       TV++ G    +V+ Y  +G  +  G  ++    +
Sbjct: 411 VA-FRSHLDVYSVESKGLLRSIDTSQTVNSVGFVTDTVLVYGGEGKVMKNGEREHASLFF 587

Query: 653 GVTDNG 658
               NG
Sbjct: 588 TDILNG 605
>29912
          Length = 510

 Score = 35.0 bits (79), Expect = 0.11,   Method: Compositional matrix adjust.
 Identities = 28/103 (27%), Positives = 47/103 (45%), Gaps = 3/103 (2%)
 Frame = +3

Query: 597 VVAVGTLTGRWFVFDTETKDLVTVHTDGNEQ-LSVMRYSPDGNFLAIGSHDNCIYIYGVT 655
           +V+ G+ +G     D    D       G+ Q +  +R+SPDG +LA G++DN + ++   
Sbjct: 171 IVSSGSRSGNIHHHDVRVADHHVGTLSGHSQEVCGLRWSPDGKYLASGANDNLLCVWPAQ 350

Query: 656 DNGRKYTR-VGKCSGHSSFITHLDWSV-NSQFLVSNSGDYEIL 696
             G   T+ +   S H + +  L W       L S  GD  I+
Sbjct: 351 VTGGNSTQPLHTFSQHQAAVKALAWCPWQPSXLASGGGDVLIV 479

 Score = 32.7 bits (73), Expect = 0.53,   Method: Compositional matrix adjust.
 Identities = 31/105 (29%), Positives = 48/105 (45%), Gaps = 1/105 (0%)
 Frame = +3

Query: 595 GSVVAVGTLTGRWFVFD-TETKDLVTVHTDGNEQLSVMRYSPDGNFLAIGSHDNCIYIYG 653
           G+ +A+GT TG   V+D T+ K L T+         V   S +   ++ GS    I+ + 
Sbjct: 45  GNYLALGTSTGEVQVWDVTQQKKLRTM---AGHAARVGSLSWNSFIVSSGSRSGNIHHHD 215

Query: 654 VTDNGRKYTRVGKCSGHSSFITHLDWSVNSQFLVSNSGDYEILYW 698
           V         VG  SGHS  +  L WS + ++L S + D  +  W
Sbjct: 216 VRVADH---HVGTLSGHSQEVCGLRWSPDGKYLASGANDNLLCVW 341
>19498
          Length = 903

 Score = 34.7 bits (78), Expect = 0.15,   Method: Compositional matrix adjust.
 Identities = 23/84 (27%), Positives = 38/84 (45%), Gaps = 13/84 (15%)
 Frame = -1

Query: 628 LSVMRYSPDGNFLAIGSHDNCIYIYGVT---DNGRKY----------TRVGKCSGHSSFI 674
           ++ +R+S +G FLA G  D  I I+ ++    +G+ +            V    GH+  +
Sbjct: 777 VNCVRWSENGKFLASGGDDKLIMIWQISRGFGSGKSFGSNVTILEHWRSVATLRGHAGDV 598

Query: 675 THLDWSVNSQFLVSNSGDYEILYW 698
             L WS    +L S S D  I+ W
Sbjct: 597 LDLAWSPQDLWLASCSVDNTIVVW 526
>13278
          Length = 870

 Score = 34.3 bits (77), Expect = 0.19,   Method: Compositional matrix adjust.
 Identities = 14/33 (42%), Positives = 21/33 (63%)
 Frame = +1

Query: 622 TDGNEQLSVMRYSPDGNFLAIGSHDNCIYIYGV 654
           T   E +  + +SPDG +LA GS D C++I+ V
Sbjct: 193 TKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNV 291
>02090
          Length = 1841

 Score = 34.3 bits (77), Expect = 0.21,   Method: Compositional matrix adjust.
 Identities = 37/164 (22%), Positives = 64/164 (39%), Gaps = 5/164 (3%)
 Frame = -3

Query: 539  QGHTDELWGLAIHASKPQFLTCGHDKHATLWDAVGHRPVWDKIIEDPAQSSGFHPSGSVV 598
            QGHTD    + I     +  T G D     WD    R +          S G+ P+G  +
Sbjct: 1509 QGHTDGASCIDISPDGTKLWTGGLDNTVRSWDLREGRQLQQHDFSSQIFSLGYCPTGEWL 1330

Query: 599  AVGTLTGRWFVFDTETKDLVTVHTDGNEQLSVMRYSPDGNFLAIGSHDNCIYIYGVTDNG 658
            AVG  +    V      D   +H   +  LS ++++  G +      DN +  +      
Sbjct: 1329 AVGMESSNVEVLHHSKPDKYQLHLHESCVLS-LKFAYCGKWFVSTGKDNLLNAWRTPYGA 1153

Query: 659  RKYTRVGKCSGHSSFITHLDWSVNSQFLVSNSGD-----YEILY 697
              +      S  SS +   D + + +++V+ SGD     YE+++
Sbjct: 1152 SIFQ-----SKESSSVLSCDIAADDKYIVTGSGDKKATLYEVIF 1036
>14500
          Length = 1238

 Score = 33.1 bits (74), Expect = 0.48,   Method: Compositional matrix adjust.
 Identities = 17/58 (29%), Positives = 30/58 (51%), Gaps = 1/58 (1%)
 Frame = +2

Query: 607 WFVFDTETKDLVTVHTDGNEQ-LSVMRYSPDGNFLAIGSHDNCIYIYGVTDNGRKYTR 663
           WF++     D       G+ Q +  +R+SPDG +LA G++DN + ++     G   T+
Sbjct: 2   WFLYYGRVADHHVGTLSGHSQEVCGLRWSPDGKYLASGANDNLLCVWPAQVTGGNSTQ 175
>25930
          Length = 419

 Score = 32.7 bits (73), Expect = 0.59,   Method: Composition-based stats.
 Identities = 18/60 (30%), Positives = 30/60 (50%)
 Frame = +1

Query: 639 FLAIGSHDNCIYIYGVTDNGRKYTRVGKCSGHSSFITHLDWSVNSQFLVSNSGDYEILYW 698
           F+A+GS    I IY V     +  R+   +G    I +L+WS+++  L+S S    +  W
Sbjct: 100 FVAVGSVRGDILIYDVRLEPWRLARIAPSNGQDDSIKNLNWSLDATRLISVSESGTLQVW 279
>34005
          Length = 456

 Score = 32.7 bits (73), Expect = 0.59,   Method: Compositional matrix adjust.
 Identities = 22/93 (23%), Positives = 43/93 (46%), Gaps = 3/93 (3%)
 Frame = +1

Query: 626 EQLSVMRYSPDGNFLAIGSHDNCIYIYGVTDNGRKYTRVGKCSGHSSFITHLDWSVNSQF 685
           +++  + +SPD  FLA GS+DN + I+  T  G     +   + H + +  + W      
Sbjct: 115 QEVCGLSWSPDATFLASGSNDNSVNIWDSTL-GMDVPPLHTLTSHQAAVKAVAWCPWQTR 291

Query: 686 LVSNSG---DYEILYWVPSACKQVVSVETTRDI 715
           +++  G   D  I +W  +    V +V+T   +
Sbjct: 292 MLATGGGTNDRHIRFWNTNTGACVKAVDTQSQV 390
>19949
          Length = 903

 Score = 32.3 bits (72), Expect = 0.75,   Method: Compositional matrix adjust.
 Identities = 21/74 (28%), Positives = 34/74 (45%)
 Frame = +2

Query: 327 VTCIAFSKSNGGGHLCAVDDSNDHVLSVWDWQKEERLADVKCSNEAVFAADFHPTDTNII 386
           V C+ FS    G  + +   S D ++ +WD    + L D+K   +AV   +FHP +  + 
Sbjct: 128 VCCLRFSPD--GRWIASA--SEDGLVKLWDLTAGKLLTDLKLHRDAVNTIEFHPHEFLLA 295

Query: 387 VTCGKSHLYFWTLE 400
                  + FW LE
Sbjct: 296 SGSADRTVKFWDLE 337
>37142
          Length = 327

 Score = 32.0 bits (71), Expect = 0.91,   Method: Compositional matrix adjust.
 Identities = 21/74 (28%), Positives = 36/74 (48%), Gaps = 2/74 (2%)
 Frame = +2

Query: 372 AVFAADFHPTDTNIIVT-CGKSHLYFWTLEGNSLNKKQGLFEKQEKPKFVLCVTFSENGD 430
           AV A DF+P  TN++ +   +S +Y W L  N  +      +K + P+ V CV ++    
Sbjct: 110 AVKALDFNPFQTNLLASGASESEIYIWDL--NKPDNPMTPGQKSQPPEEVSCVAWNRQVQ 283

Query: 431 TITGDS-SGNILVW 443
            I   + +   +VW
Sbjct: 284 HILASNFAARCVVW 325
>02147
          Length = 1547

 Score = 31.6 bits (70), Expect = 1.4,   Method: Compositional matrix adjust.
 Identities = 54/298 (18%), Positives = 106/298 (35%), Gaps = 15/298 (5%)
 Frame = +2

Query: 531 SGDFTPITQGHTDELWGLAIHASKPQFLTCGHDKHATLWDAVGHRPVWDKIIEDPAQSSG 590
           +GD+    +GH   +WG  ++    +  T   D  A +WDA           E   +   
Sbjct: 140 TGDWIGTFEGHKGAVWGATLNREATRAATGAADFSAKIWDA-----------EKGEELQT 286

Query: 591 FHPSGSVVAVGTLTGRWFVFDTETKDLVTVHTDGNEQLSVMRYSPDGNFLAIGSHDNCIY 650
           F     V +V                                +S DG  L  GS++  + 
Sbjct: 287 FSHKHIVKSV-------------------------------DFSHDGTALLTGSNEKLLK 373

Query: 651 IYGVTDNGRKYTRVGKCSGHSSFITHLDWSVNSQFLVSNSGDYEILYWVPSACKQV---- 706
           ++ + +           +GH+S I    +  + + ++S S D  +  W    C++V    
Sbjct: 374 VFDLVNTD---AEPKSFAGHTSNIKGALFLSDGKRIISASDDKTVRLWSLETCQEVQQLT 544

Query: 707 -------VSVETTRDIEWATYTCTLGFHVFGVWPE----GSDGTDINAVCRAHERKLLCT 755
                  +++   ++    T++  + F+      E     ++    +A     ER  +  
Sbjct: 545 FDTPPTSLTLSPDKNTIIVTHSQNIAFYQADTLREMKKFEAEAPISSASLHQSERFFVAG 724

Query: 756 GDDFGKVHLFSYPCSQFRAPSHIYSGHSSHVTNVDFLCEDSHLISTGGKDTSIMQWRV 813
           G+DF K++ F Y   +       + GH   V  V F   D  L ++G +D ++  W+ 
Sbjct: 725 GEDF-KMYKFDYETGK---EIESFKGHFGPVHCVRF-SPDGELYASGSEDGTLRLWQT 883
>00825
          Length = 1821

 Score = 31.2 bits (69), Expect = 1.9,   Method: Compositional matrix adjust.
 Identities = 35/166 (21%), Positives = 66/166 (39%), Gaps = 6/166 (3%)
 Frame = -2

Query: 538  TQGHTDELWGLAIHASKPQFLTCGHDKHATLWD-----AVGHRPVWDKIIEDPAQSSGFH 592
             Q H   + G+A H+S   F +CG DK    W       +   PV   + +    S   H
Sbjct: 1757 VQAHDGIVHGMAAHSSGQYFFSCGSDKTIKQWSLDPEGTIAPEPVNTLLAKCIYTSLDHH 1578

Query: 593  PSGSVVAVGTLTGRWFVFDTETKDLVTVHTDGNEQLSVMRYSP-DGNFLAIGSHDNCIYI 651
                +    T   R  V+D +  + +   + G E +  ++++P +   L   +HD  I +
Sbjct: 1577 WKDDIFV--TSGSRVDVWDEKRSEPMRSFSWGVESVHHVKFNPVETYLLGAAAHDRSILL 1404

Query: 652  YGVTDNGRKYTRVGKCSGHSSFITHLDWSVNSQFLVSNSGDYEILY 697
            Y +  +      V K   ++     L W+    F ++++ +   LY
Sbjct: 1403 YDMRGSAPLRKVVMKMRTNA-----LSWNPMEAFTITSANEDGNLY 1281
>01598
          Length = 1545

 Score = 30.0 bits (66), Expect = 4.4,   Method: Compositional matrix adjust.
 Identities = 19/66 (28%), Positives = 29/66 (43%)
 Frame = +1

Query: 748  HERKLLCTGDDFGKVHLFSYPCSQFRAPSHIYSGHSSHVTNVDFLCEDSHLISTGGKDTS 807
            H+ +L+  G D      F +   +  A +  + GH   +    F   D  L+ TGG D S
Sbjct: 1336 HDARLVSVGYD---AEAFVWDVQKGTALAQ-FKGHMGRLLTCQFSGLDPDLVMTGGSDAS 1503

Query: 808  IMQWRV 813
            +  WRV
Sbjct: 1504 VHVWRV 1521

 Score = 29.6 bits (65), Expect = 5.2,   Method: Compositional matrix adjust.
 Identities = 32/142 (22%), Positives = 55/142 (38%), Gaps = 22/142 (15%)
 Frame = +1

Query: 579  DKIIEDPAQSSGFHPSGSVVAVGTLTGRWFVFDTETKDLVTVHTDGNEQLSVMRY----- 633
            D++    A    + P  +  AVGT  G  +V   +   +V       + ++ +R+     
Sbjct: 961  DQVKGLKATELSWSPDQNAAAVGTDEGSVYVVTIQDLKIVAAIRTQQKLINCVRWHPRLT 1140

Query: 634  ------SPDGNFLAIGSHDNCIYIY----------GVTDNGRKYTRVGKCSGHSSFITHL 677
                  SP  ++LA   +D  I++           G  +     T + + SGHS  +T +
Sbjct: 1141 DQSPAGSPCCHWLAAAGNDQVIHVVDLASVFAEREGDKETSLILTSLRELSGHSQRVTDM 1320

Query: 678  DWSVNSQF-LVSNSGDYEILYW 698
             WS +    LVS   D E   W
Sbjct: 1321 SWSPHHDARLVSVGYDAEAFVW 1386
>10264
          Length = 416

 Score = 29.6 bits (65), Expect = 5.5,   Method: Compositional matrix adjust.
 Identities = 19/66 (28%), Positives = 29/66 (43%)
 Frame = -1

Query: 748 HERKLLCTGDDFGKVHLFSYPCSQFRAPSHIYSGHSSHVTNVDFLCEDSHLISTGGKDTS 807
           H+ +L+  G D      F +   +  A +  + GH   +    F   D  L+ TGG D S
Sbjct: 209 HDARLVSVGYD---AEAFVWDVQKGTALAQ-FKGHMGRLLTCQFSGLDPDLVMTGGSDAS 42

Query: 808 IMQWRV 813
           +  WRV
Sbjct: 41  VHVWRV 24
>03044
          Length = 1952

 Score = 29.3 bits (64), Expect = 6.9,   Method: Compositional matrix adjust.
 Identities = 17/70 (24%), Positives = 32/70 (45%)
 Frame = -2

Query: 625  NEQLSVMRYSPDGNFLAIGSHDNCIYIYGVTDNGRKYTRVGKCSGHSSFITHLDWSVNSQ 684
            N   + +++SP+ N  A+GS    I +    +  R +          S +T LDW  N+ 
Sbjct: 1522 NRAATCVKWSPEENKFAVGSSARLISVSYYEEEHRWWVSKHIKKPIRSTVTCLDWHPNNI 1343

Query: 685  FLVSNSGDYE 694
             + + S D++
Sbjct: 1342 LIAAGSTDFK 1313
>02948
          Length = 1207

 Score = 28.9 bits (63), Expect = 7.8,   Method: Compositional matrix adjust.
 Identities = 23/87 (26%), Positives = 34/87 (39%), Gaps = 9/87 (10%)
 Frame = -2

Query: 267 AGHNDDVKCLAVHPDRITIATGQVAGTSKDGKQLPPHVRIW-----DSVTLNTLHVIGIG 321
           A +N    C++ HP  + IATG  +G           +  W     D   L+  H     
Sbjct: 765 AQNNAAFTCVSCHPTDVCIATGHASGK----------ITFWWNFDQDKTVLSVSH----- 631

Query: 322 FFDRAVTCIAFSKSN----GGGHLCAV 344
           +    VTC+AF+        GGH C +
Sbjct: 630 WHSLPVTCLAFTPEGSCLLSGGHECTL 550
>17266
          Length = 480

 Score = 28.9 bits (63), Expect = 8.2,   Method: Compositional matrix adjust.
 Identities = 30/109 (27%), Positives = 50/109 (45%), Gaps = 1/109 (0%)
 Frame = -1

Query: 255 LYNVEEQL-QRHYAGHNDDVKCLAVHPDRITIATGQVAGTSKDGKQLPPHVRIWDSVTLN 313
           L++V + + ++ ++GH  D+  +   P+    ATG     S D       +R    + + 
Sbjct: 381 LWDVRDGMCKQTFSGHESDINAITYFPNGHAFATG-----SDDATCRLFDIRADQEIGMY 217

Query: 314 TLHVIGIGFFDRAVTCIAFSKSNGGGHLCAVDDSNDHVLSVWDWQKEER 362
           +   I  G     +T +AFSKS G   L   DD N    ++WD  K+ER
Sbjct: 216 SHDNIICG-----ITSVAFSKS-GRLLLGGYDDFN---CNIWDVLKQER 97
>17598
          Length = 875

 Score = 28.9 bits (63), Expect = 8.3,   Method: Compositional matrix adjust.
 Identities = 40/195 (20%), Positives = 72/195 (36%), Gaps = 17/195 (8%)
 Frame = +1

Query: 477 GGKDRRLISWNGNYQKLHKAEIPEQFGPIRTVAEGKGNVIL---IGTTRNFVLQGTL--- 530
           GG+D+ LI W+   +K    +  E +G  R   +G  + +    +     +VL  +    
Sbjct: 19  GGRDKLLIVWDLVPRK--DGDEDETWGGPRRTLQGHSHFVSDVSLSADSRYVLSSSWDAT 192

Query: 531 -------SGDFTPITQGHTDELWGLAIHASKPQFLTCGHDKHATLWDAVGH--RPVWDKI 581
                   G+ T     HT +   +A      Q  + G DK   +W+ VG     V    
Sbjct: 193 LRLWDIKKGNTTRRFISHTRDALAVAFSPDNRQIASGGRDKALKIWNTVGECKFTVDANS 372

Query: 582 IEDPAQSSGFHPSGS--VVAVGTLTGRWFVFDTETKDLVTVHTDGNEQLSVMRYSPDGNF 639
            +D      FH      +V   ++     V+D +T  L         Q++ +  +    +
Sbjct: 373 HQDWVTCVKFHQDAKSPLVVSASMDKTIKVWDNQTMTLKHTFVGHKTQINAIDLALKTYY 552

Query: 640 LAIGSHDNCIYIYGV 654
           LA GS D  +  + +
Sbjct: 553 LASGSKDGIVMTWNI 597
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|21703888|ref|NP_663420.1| eukaryotic translation
initiation factor 2B, subunit 2 beta [Mus musculus]
         (351 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

03417                                                                 101   6e-22
13316                                                                  51   6e-07
25770                                                                  29   2.7  
>03417
          Length = 1133

 Score =  101 bits (251), Expect = 6e-22,   Method: Compositional matrix adjust.
 Identities = 70/226 (30%), Positives = 108/226 (47%), Gaps = 6/226 (2%)
 Frame = -3

Query: 126  FAPLKANIIEAINELLVELEGTMENIAAQALEHIHSNEVIMTIGYSRTV-EAFLKEAARK 184
            F   + N+I+   + +  +    + IA  A   I +N +++T  YSR V E F K   + 
Sbjct: 1020 FERSRQNMIQLGRKWVNNMANARQTIARLAEPFIPNNTILLTHSYSRVVMEVFRKAVEKG 841

Query: 185  RKFHVIVAECAPFCQGHEMAVNLSKEGIETTVMTDAAIFAVMSRVNKVIIGTKTILANGS 244
            + F V V E  P   G   A  L   G++ T++ DA++  +M  V  V++G + +L NG 
Sbjct: 840  KTFKVYVCESQPDQAGRRTAKELRDMGLKCTIILDASVGYIMETVTMVVVGAENLLKNGG 661

Query: 245  LRAVAGTHTLALAAKHHSTPLIVCAPMFKLSPQFPSEEDSFHKFVAPEEVLPFTEGDILE 304
            +    GT+++A+AAK +  PL V A   K    FP E+DS      P + L F + D+ +
Sbjct: 660  IFNKIGTYSIAIAAKKYHRPLYVFAESLKYMEYFPLEQDSI-----PSD-LKFKKADVED 499

Query: 305  K-----VSVHCPVFDYVPPDLITLFISNIGGNAPSYIYRLMSELYH 345
                  +    P+ DY PP  I   IS+IG      I   M  LYH
Sbjct: 498  AEEEGLMEDEHPLIDYTPPKYINRLISDIGVLPSHAICDEMMSLYH 361
>13316
          Length = 1362

 Score = 51.2 bits (121), Expect = 6e-07,   Method: Compositional matrix adjust.
 Identities = 38/136 (27%), Positives = 64/136 (47%), Gaps = 5/136 (3%)
 Frame = +2

Query: 212 IETTVMTD--AAIFAVMSRVNKVIIGTKTILANGSLRAVAGTHTLALAAKHHSTPLIVCA 269
           ++ T++ D  AAI     +++ V++G   ++ANG      GT+ LA+ AKHH  P  V  
Sbjct: 764 MDATLVCDSMAAILMKQKKISAVVVGADRVVANGDTANKVGTYQLAIVAKHHKVPFYVAC 943

Query: 270 PMFKLSPQFPSEEDSFHKFVAPEEVLPFTEGDILEKVSVHC--PVFDYVPPDLIT-LFIS 326
           P+        S +D   +   P   +   +G  L    + C  P FD  P +LIT   I+
Sbjct: 944 PLTTYDGSKASGDDIIIEE-RPAVEMTSIKGVRLAAEGIKCWNPAFDVTPAELITGGIIT 1120

Query: 327 NIGGNAPSYIYRLMSE 342
             G   PS + + +++
Sbjct: 1121EFGVFPPSKLSQALAQ 1168
>25770
          Length = 653

 Score = 29.3 bits (64), Expect = 2.7,   Method: Compositional matrix adjust.
 Identities = 12/27 (44%), Positives = 18/27 (66%)
 Frame = -1

Query: 264 PLIVCAPMFKLSPQFPSEEDSFHKFVA 290
           PLI+  P+F  +P FP+ E +F  FV+
Sbjct: 227 PLILICPIFSYNPCFPNNEHNFMCFVS 147
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|113680352|ref|NP_031646.2| carbonyl reductase 1 [Mus
musculus]
         (277 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

05023                                                                 100   7e-22
03060                                                                  63   2e-10
30930                                                                  55   3e-08
03983                                                                  48   5e-06
27168                                                                  45   3e-05
11922                                                                  44   1e-04
35613                                                                  43   1e-04
23588                                                                  38   0.005
12758                                                                  37   0.010
28229                                                                  28   0.50 
36378                                                                  31   0.52 
12677                                                                  30   1.0  
30783                                                                  30   1.4  
26417                                                                  30   1.4  
>05023
          Length = 1171

 Score =  100 bits (248), Expect = 7e-22,   Method: Compositional matrix adjust.
 Identities = 46/82 (56%), Positives = 64/82 (78%)
 Frame = +1

Query: 196 VTKIGVTVLSRILARKLNEQRRGDKILLNACCPGWVRTDMAGPKATKSPEEGAETPVYLA 255
           V+KIGVTVLS +  R+++ + + D I++NACCPG+V TDM+  K TK+ ++GAETPV LA
Sbjct: 1   VSKIGVTVLSILQQRQMDAEXK-DDIIVNACCPGYVDTDMSSHKGTKTIDQGAETPVMLA 177

Query: 256 LLPPDAEGPHGQFVQDKKVEPW 277
           LLPP+A+ P G FV +KKV+ W
Sbjct: 178 LLPPNADSPRGNFVSEKKVQKW 243
>03060
          Length = 1893

 Score = 62.8 bits (151), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 42/143 (29%), Positives = 77/143 (53%), Gaps = 8/143 (5%)
 Frame = -1

Query: 7    VALVTGANKGIGFAITRDLCRKFSGDVVLAARDEERGQTAVQKL-----QAEGLSPRFHQ 61
            V LVTGA+ G+G A  +    +    V+LA R  ER       L     + +   P    
Sbjct: 1683 VVLVTGASSGLGKACAKVF-HQHGCQVILAGRSVERLNAVKDYLTKSEGEVKACEPSVLA 1507

Query: 62   LDIDNPQSIRALRDFLLKEYGGLDVLVNNAGIAFK-VNDDTPFHIQAEVTMKTNFFGTRD 120
            +D+++  S++ L +  ++ +G +DV++NNAGI+++   +DT   +  ++ M  N+FG   
Sbjct: 1506 MDLEDLNSLQQLAERAVELFGKVDVVINNAGISYRGCIEDTSIQVDQKL-MAVNYFGHVA 1330

Query: 121  VCKELLPLIKPQ--GRVVNVSSM 141
            + K LLP ++ +  G +V +SS+
Sbjct: 1329 LIKGLLPHMQARNSGHIVGISSV 1261
>30930
          Length = 1452

 Score = 55.1 bits (131), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 49/162 (30%), Positives = 75/162 (46%), Gaps = 4/162 (2%)
 Frame = -3

Query: 1    MSSSRPVALVTGANKGIGFAITRDLCRKFSGDVVLAARDEERGQTAVQKLQAEGLSPRFH 60
            +SS+    L+TG ++G GF   + L     G  V A   +  G+ A Q L+    +    
Sbjct: 1369 LSSTGKAVLITGCDRGFGFLSAQRLSSL--GYRVFAGCFDATGEGAAQ-LRLTSPNIDVI 1199

Query: 61   QLDIDNPQSIRALRDFL---LKEYGGLDVLVNNAGIAFKVNDDTPFHIQAEVTMKTNFFG 117
            QLD+ N   +   R F    L+ YG L  +VNNAG  F    +     + +  M  N+ G
Sbjct: 1198 QLDVTNDGQVEEARRFXDEQLQGYG-LWAIVNNAGTLFGAEVEWCSLSRXQRMMDVNWLG 1022

Query: 118  TRDVCKELLPLIKP-QGRVVNVSSMVSLRALKNCRLELQQKF 158
            T  + +  LP ++  +GRV+NV+S+    AL    L    KF
Sbjct: 1021 TVRITQAFLPYVRSVKGRVINVASLSGRVALPGYALYSSTKF 896
>03983
          Length = 1099

 Score = 47.8 bits (112), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 57/223 (25%), Positives = 97/223 (43%), Gaps = 9/223 (4%)
 Frame = +2

Query: 9   LVTGANKGIGFAITRDLCRKFSG---DVVLAARDEERGQTAVQKLQAEGLSPRFHQLDID 65
           L+TGA  G+G    + +  +F G   D+VL   + E  + A+++   + +S + + +D+ 
Sbjct: 188 LITGAGSGLG----KLMAYRFMGLGCDLVLWDINTEAIE-AMERDMGQQVSCKAYTVDLS 352

Query: 66  NPQSIRALRDFLLKEYGGLDVLVNNAGIA----FKVNDDTPFHIQAEVTMKTNFFGTRDV 121
           + + I    D + +E GG+D+LVNNAGI     F    D+      EV    +F+     
Sbjct: 353 SREQIYKAADQVKREVGGVDILVNNAGIVTGRKFLDCPDSLIEKTMEVNSNAHFWTV--- 523

Query: 122 CKELLP--LIKPQGRVVNVSSMVSLRALKNCRLELQQKFRSETITEEELVGLMNKFVEDT 179
            K  LP  L + +G +++++S   L  +         KF +    E     L  +     
Sbjct: 524 -KAFLPNMLAQNKGHIISIASSAGLFGVTGLADYCASKFAAVGFDES----LRFELEAMG 688

Query: 180 KKGVHAEEGWPNSAYGVTKIGVTVLSRILARKLNEQRRGDKIL 222
           K GVH     P         GV     ++   LN +R  DKI+
Sbjct: 689 KTGVHTTVVCPYFINTGMFDGVKTRFPLILPILNPERTVDKIM 817
>27168
          Length = 665

 Score = 45.1 bits (105), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 28/91 (30%), Positives = 47/91 (51%), Gaps = 4/91 (4%)
 Frame = +3

Query: 7   VALVTGANKGIGFAITRDLCRKFSGDVVLAARDEERGQTAVQKLQAEGLSPRFH----QL 62
           VAL+TGAN GIGF   R L      +++LA R+    Q A+ ++  E  + R       L
Sbjct: 192 VALITGANCGIGFETARSLALH-GCEIILACRNLATAQEAIDRIAVERPAARARCRTASL 368

Query: 63  DIDNPQSIRALRDFLLKEYGGLDVLVNNAGI 93
           D+ +   ++   + + +  G +D L+ NAG+
Sbjct: 369 DLGSLSDVKKFVEQIRQSVGHIDYLILNAGV 461
>11922
          Length = 2153

 Score = 43.5 bits (101), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 43/185 (23%), Positives = 80/185 (43%), Gaps = 25/185 (13%)
 Frame = +1

Query: 9   LVTGANKGIGFAITRDLCRKFSGDVVLAARDEERG-------QTAVQKLQAEGLSPRFHQ 61
            +TGA++GIG AI   L +    ++V+AA+  E          TA ++++  G       
Sbjct: 112 FITGASRGIGKAIAVKLAKD-GANIVIAAKTAEAHPKLPGTIYTAAKEVEEAGGKALPCI 288

Query: 62  LDIDNPQSIRALRDFLLKEYGGLDVLVNNA-GIAFKVNDDTPFHIQAEVTMKTNFFGTRD 120
           +DI N   ++        ++GG+D+LVNNA  I+      TP   + ++    N  GT  
Sbjct: 289 VDIRNEDQVKVAVKAAADKFGGIDILVNNASAISLTGTLQTPMK-RYDLMNGINARGTYL 465

Query: 121 VCKELLPLI--KPQGRVVNVSSMVSLRA---------------LKNCRLELQQKFRSETI 163
             +  LP +       ++N+S  +++ A               +  C L + ++FR + +
Sbjct: 466 CSQVCLPYLLRGSNPHILNISPPLNMSAKWFQGHVAYTMAKYGMSMCALGMAEEFRDDGV 645

Query: 164 TEEEL 168
               L
Sbjct: 646 AVNAL 660
>35613
          Length = 977

 Score = 43.1 bits (100), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 37/136 (27%), Positives = 63/136 (46%), Gaps = 3/136 (2%)
 Frame = +1

Query: 9   LVTGANKGIGFAITRDLCRKFSGDVVLAARDEERGQTAVQKLQAEGLSPRFHQLDIDNPQ 68
           L+TG + G G A+ + L       +    + +  G   ++ +  + ++     LD+ +  
Sbjct: 97  LITGCDTGFGHALAKSLHEDGCHVIATVYQPDGDGAKRLRDVSTDRMT--VIPLDVSSDD 270

Query: 69  SI-RALRDF-LLKEYGGLDVLVNNAGIAFKVNDDTPFHIQAEVTMKTNFFGTRDVCKELL 126
           S+ + LR    L E+ GL  LVNNAG  F    +     Q  +    N FG     +  L
Sbjct: 271 SVEKCLRHVKQLCEHSGLWGLVNNAGHNFVGEVELTTMRQYLMVANINIFGMVRTTRAFL 450

Query: 127 PLIK-PQGRVVNVSSM 141
           PL++   GR+VNV+S+
Sbjct: 451 PLLRHATGRIVNVTSI 498
>23588
          Length = 611

 Score = 37.7 bits (86), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 33/115 (28%), Positives = 52/115 (45%), Gaps = 4/115 (3%)
 Frame = +3

Query: 35  LAARDEERGQTAVQKLQAEGLSPR---FHQLDIDNPQSIRALRDFLLKEYGGLDVLVNNA 91
           L  RD  + +  VQK  A G+ P        D+ +    + L    + ++G +DVLVNNA
Sbjct: 54  LTGRDATKLENVVQKCVAAGVKPTDVVTVAGDLTDETFRQQLVASTVDKFGQIDVLVNNA 233

Query: 92  GIAFKVNDDTPFHIQAEVTMKTNFFGTRDVCKELLP-LIKPQGRVVNVSSMVSLR 145
           G A       P           N      + K  +P L++ +G +VN+SS +S+R
Sbjct: 234 GFANPGLLSBPGMENLLNVFSLNLNAHVAMSKLCVPHLLQSKGNIVNISSNLSMR 398
>12758
          Length = 804

 Score = 37.0 bits (84), Expect = 0.010,   Method: Compositional matrix adjust.
 Identities = 24/73 (32%), Positives = 38/73 (52%), Gaps = 1/73 (1%)
 Frame = -1

Query: 78  LKEYGGLDVLVNNAGIAFKVNDDTPFHIQAEVTMKTNFFGTRDVCKELLP-LIKPQGRVV 136
           +K++G L++LVN AGI    N +     Q +    TN      +    +P L+  QG +V
Sbjct: 672 VKQFGRLNILVNCAGIIELGNIENTSLDQYDRMFNTNVRSVYHLTMLAVPHLVNTQGNIV 493

Query: 137 NVSSMVSLRALKN 149
           NVSS+  +R+  N
Sbjct: 492 NVSSVNGMRSFPN 454
>28229
          Length = 633

 Score = 27.7 bits (60), Expect(2) = 0.50,   Method: Compositional matrix adjust.
 Identities = 27/82 (32%), Positives = 39/82 (47%), Gaps = 1/82 (1%)
 Frame = -2

Query: 13  ANKGIGFAITRDLCRKFSGDVV-LAARDEERGQTAVQKLQAEGLSPRFHQLDIDNPQSIR 71
           A+ GIG AI + L R+  G V+ L  R+    +     LQ +    +   +  D      
Sbjct: 632 ASSGIGVAIAQVLARE--GAVLSLVGRNVTNLEATRTTLQQQTTGVQVLNVVADVTTDSA 459

Query: 72  ALRDFLLKEYGGLDVLVNNAGI 93
           A+    +  YG +DVLVNNAGI
Sbjct: 458 AIIQQTINHYGRIDVLVNNAGI 393

 Score = 21.9 bits (45), Expect(2) = 0.50,   Method: Compositional matrix adjust.
 Identities = 12/23 (52%), Positives = 15/23 (65%), Gaps = 1/23 (4%)
 Frame = -1

Query: 123 KELLP-LIKPQGRVVNVSSMVSL 144
           K  LP L+K +G VVNVSS   +
Sbjct: 306 KAALPHLLKTKGAVVNVSSCAGI 238
>36378
          Length = 552

 Score = 31.2 bits (69), Expect = 0.52,   Method: Compositional matrix adjust.
 Identities = 17/59 (28%), Positives = 33/59 (55%), Gaps = 1/59 (1%)
 Frame = -3

Query: 77  LLKEYGGLDVLVNNAGIAFKVN-DDTPFHIQAEVTMKTNFFGTRDVCKELLPLIKPQGR 134
           +L+ +G +D+LVNNAG + +     T   +  ++ ++ N  G   + K +LP +  +GR
Sbjct: 385 VLQHFGQIDILVNNAGRSQRAEWVKTSLDVDRQM-LELNVLGVLSLTKAVLPHMMQRGR 212
>12677
          Length = 1101

 Score = 30.0 bits (66), Expect = 1.0,   Method: Compositional matrix adjust.
 Identities = 20/63 (31%), Positives = 31/63 (49%), Gaps = 2/63 (3%)
 Frame = -2

Query: 33   VVLAARDEERGQTAVQKLQAEGLSPRFHQLDIDNP--QSIRALRDFLLKEYGGLDVLVNN 90
            + LA R++ R  TA Q LQA         + ID    +S+    + + K+Y  +D L  N
Sbjct: 1076 LCLACRNKHRADTARQSLQASYPDATIDVVIIDTSSVKSVLEAAEVMKKKYIHIDFLYLN 897

Query: 91   AGI 93
            AG+
Sbjct: 896  AGV 888
>30783
          Length = 765

 Score = 29.6 bits (65), Expect = 1.4,   Method: Compositional matrix adjust.
 Identities = 19/53 (35%), Positives = 31/53 (58%), Gaps = 4/53 (7%)
 Frame = +2

Query: 78  LKEYGGLDVLVNNAGIA--FKVNDDTP--FHIQAEVTMKTNFFGTRDVCKELL 126
           +  +G LD+LVNNAG+A   K  D T   +    ++ MK+ FF ++ +  EL+
Sbjct: 14  ISTFGRLDILVNNAGVARFVKPCDTTEEQYDEIMDINMKSVFFLSKLLAPELI 172
>26417
          Length = 929

 Score = 29.6 bits (65), Expect = 1.4,   Method: Compositional matrix adjust.
 Identities = 51/215 (23%), Positives = 88/215 (40%), Gaps = 22/215 (10%)
 Frame = +1

Query: 84  LDVLVNNAGI---AFKVNDDTPFHIQAEVTMKTNFFGTRDVCKELLPLIKPQG--RVVNV 138
           +D+L+NNAG+    + + +D       E    TN FG   +   LL  +K     R++NV
Sbjct: 10  VDILINNAGVIGLPYALTED-----GLETNFATNHFGPFLLTNLLLDKLKSSAPSRIINV 174

Query: 139 SSMVSLRALKNCRLELQQKFRSETITEEELVGLMNKFVEDTKKGVHAEEGWPNSAYGVTK 198
           SS+V     K  +++L    ++E   +E  +                        Y  +K
Sbjct: 175 SSVVQ----KAGKIDLDN-LKAEKYFKEHKI------------------------YFNSK 267

Query: 199 IGVTVLSRILARKLNEQRRGDKILLNACCPGWVRTDM---------AGPKATK----SPE 245
           +   + +R LAR+L      D + ++   PG  +TD+          G K  +    SP 
Sbjct: 268 LANVLFTRELARRLVATGVTD-VTVHCLHPGSXKTDLLNNMPWYVRYGMKLVRVFLLSPL 444

Query: 246 EGAETPVYLALLPPDAEGPHGQFVQ----DKKVEP 276
           EGA+T ++ A+     +     F Q    D++V P
Sbjct: 445 EGAQTTLFCAMAEEVKDMSGKYFAQCQLADRQVNP 549
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|28077027|ref|NP_083009.1| protein kinase C and casein
kinase substrate in neurons 3 [Mus musculus]
         (424 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

14893                                                                 100   8e-22
17800                                                                  94   1e-19
29687                                                                  47   1e-05
28095                                                                  47   1e-05
01494                                                                  45   5e-05
12324                                                                  43   3e-04
16716                                                                  42   6e-04
30482                                                                  38   0.006
13664                                                                  38   0.007
15115                                                                  37   0.014
30740                                                                  33   0.31 
19469                                                                  32   0.34 
05206                                                                  30   1.5  
31183                                                                  29   4.0  
>14893
          Length = 403

 Score =  100 bits (250), Expect = 8e-22,   Method: Compositional matrix adjust.
 Identities = 50/118 (42%), Positives = 74/118 (62%), Gaps = 2/118 (1%)
 Frame = +1

Query: 220 YMEDMEQAFESCQAAERQRLLFFKDVLLTLHQHLDLSSSDKFHELHRDLQQSIEAASDEE 279
           Y+EDM + ++ CQ  ER R+ FFK     LH+ LDLS   ++  ++ DL  +I     + 
Sbjct: 1   YIEDMTEVYDKCQEFERTRIEFFKATFFKLHKCLDLSVESEYARVYTDLHATITNTDPDR 180

Query: 280 DLRWWRSTHGPGMAMNWPQFEEWSLDTQRAISRKEKGGRSPDE--VTLTSIVPTRDGT 335
           DL++W ++HG  MAM WPQFEE+S + Q AIS+K KG  S  E  +T+TSI  +R+ +
Sbjct: 181 DLKYWSTSHGIDMAMAWPQFEEYSPELQ-AISKKGKGAVSTGEGGITITSIRHSRESS 351
>17800
          Length = 451

 Score = 93.6 bits (231), Expect = 1e-19,   Method: Compositional matrix adjust.
 Identities = 36/91 (39%), Positives = 54/91 (59%)
 Frame = +2

Query: 213 LNRYTPRYMEDMEQAFESCQAAERQRLLFFKDVLLTLHQHLDLSSSDKFHELHRDLQQSI 272
           + +Y   Y+EDM   FE CQ  E+ RL FFK+VL  +H  LD +      +++ +   +I
Sbjct: 2   ITKYNSVYIEDMTSVFEKCQTMEKTRLQFFKEVLFNVHSTLDTTKVQSLPQIYDEFYHTI 181

Query: 273 EAASDEEDLRWWRSTHGPGMAMNWPQFEEWS 303
             A  ++DL+WW + HG  MAMNWP F E++
Sbjct: 182 NNADQQKDLKWWSNNHGINMAMNWPAFVEYT 274
>29687
          Length = 434

 Score = 47.0 bits (110), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 24/63 (38%), Positives = 37/63 (58%)
 Frame = -2

Query: 358 SPRKVATGVRVRALYDYAGQEADELSFRAGEELLKMSEEDEQGWCQGQLQSGRIGLYPAN 417
           +P    T +RV+AL+DY  +  DELSF  G  +  +S +D  GW +G   + +   +P+N
Sbjct: 322 NPNDFTTKLRVKALHDYNAKREDELSFCKGAIITNVSRQD-GGWWRGDYGTKKQHWFPSN 146

Query: 418 YVE 420
           YVE
Sbjct: 145 YVE 137
>28095
          Length = 597

 Score = 47.0 bits (110), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 21/57 (36%), Positives = 38/57 (66%), Gaps = 1/57 (1%)
 Frame = +3

Query: 365 GVRVRALYDYAGQEADELSFRAGEELLKMSEEDEQGWCQGQLQ-SGRIGLYPANYVE 420
           G+  +A+YDY   ++DE+SF  G+ +++    D  GW  G+++ +G+ G+ P+NYVE
Sbjct: 255 GMVCKAMYDYQAADSDEVSFNDGDTIIECQPVD-AGWMTGRVERTGQYGMLPSNYVE 422
>01494
          Length = 2122

 Score = 45.4 bits (106), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 23/63 (36%), Positives = 36/63 (57%)
 Frame = +3

Query: 358 SPRKVATGVRVRALYDYAGQEADELSFRAGEELLKMSEEDEQGWCQGQLQSGRIGLYPAN 417
           +P    T +RV+AL+DY     DELSF  G  +  +S +D  GW +G   + +   +P+N
Sbjct: 282 NPNDFTTKLRVKALHDYNANRDDELSFCKGAIITNVSRQD-GGWWRGDYGAKKQHWFPSN 458

Query: 418 YVE 420
           +VE
Sbjct: 459 FVE 467
>12324
          Length = 946

 Score = 42.7 bits (99), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 22/57 (38%), Positives = 36/57 (63%), Gaps = 1/57 (1%)
 Frame = +3

Query: 367 RVRALYDYAGQEADELSFRAGEELLKMSEEDEQGWCQGQLQSGRIGLYPANYVE-CV 422
           +V A+YDY  ++ DEL+F     +  + + D+ GW +G +  G  GL+P+NYVE C+
Sbjct: 693 KVVAIYDYEAEKDDELTFSENSVIYVIRKNDD-GWWEG-VMDGVTGLFPSNYVEPCM 857
>16716
          Length = 934

 Score = 41.6 bits (96), Expect = 6e-04,   Method: Compositional matrix adjust.
 Identities = 23/56 (41%), Positives = 32/56 (57%)
 Frame = -1

Query: 365 GVRVRALYDYAGQEADELSFRAGEELLKMSEEDEQGWCQGQLQSGRIGLYPANYVE 420
           G    ALYDY   + DEL+F   + +  +   D+ GW +G    G+ GL+PANYVE
Sbjct: 472 GSTAIALYDYQAADDDELTFDPDDVITDIEMIDD-GWWRGSCH-GKNGLFPANYVE 311
>30482
          Length = 610

 Score = 38.1 bits (87), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 17/58 (29%), Positives = 30/58 (51%), Gaps = 3/58 (5%)
 Frame = +3

Query: 366 VRVRALYDYAGQEADELSFRAGEELLKMSEEDEQG---WCQGQLQSGRIGLYPANYVE 420
            R RAL+ +  +  DEL+   G+++       E G   W +G+ + G++G +P  Y E
Sbjct: 123 TRYRALFPFESRSEDELNINTGDDIWVWDVPSEPGMEEWFKGETKDGKVGWFPQAYAE 296
>13664
          Length = 507

 Score = 38.1 bits (87), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 17/47 (36%), Positives = 29/47 (61%)
 Frame = +2

Query: 367 RVRALYDYAGQEADELSFRAGEELLKMSEEDEQGWCQGQLQSGRIGL 413
           +V ALYDY  Q +DEL+  +G+ ++ +  +D + W  G+L  G+ G 
Sbjct: 368 KVVALYDYKAQRSDELTILSGDVIMLL-HKDSESWWMGELLDGQQGF 505
>15115
          Length = 443

 Score = 37.0 bits (84), Expect = 0.014,   Method: Compositional matrix adjust.
 Identities = 16/42 (38%), Positives = 25/42 (59%)
 Frame = -2

Query: 381 ELSFRAGEELLKMSEEDEQGWCQGQLQSGRIGLYPANYVECV 422
           E++F   + +  + + DE GW QG    G  G++PANYVE +
Sbjct: 412 EITFDPDDIITNIDQIDE-GWWQGFAPDGSYGMFPANYVELL 290
>30740
          Length = 488

 Score = 32.7 bits (73), Expect = 0.31,   Method: Compositional matrix adjust.
 Identities = 14/46 (30%), Positives = 30/46 (65%)
 Frame = +2

Query: 372 YDYAGQEADELSFRAGEELLKMSEEDEQGWCQGQLQSGRIGLYPAN 417
           YD++G++ ++L F  G+ +L++  +DE+ W   + + GR+G  P +
Sbjct: 203 YDFSGRDPEDLPFSKGD-ILELISKDEEEWWTARDKHGRVGQDPLS 337
>19469
          Length = 428

 Score = 32.3 bits (72), Expect = 0.34,   Method: Compositional matrix adjust.
 Identities = 20/57 (35%), Positives = 33/57 (57%), Gaps = 3/57 (5%)
 Frame = -1

Query: 369 RALYDYAGQEADELSFRAGEELLKMSEEDE---QGWCQGQLQSGRIGLYPANYVECV 422
           +ALYD   +  DEL+FR G +++ + E+D     GW    L+ GR G+ P N ++ +
Sbjct: 356 KALYDNIAETPDELAFRRG-DVITILEQDTAGLDGWWLCSLR-GRQGIAPGNRLKIL 192
>05206
          Length = 1075

 Score = 30.4 bits (67), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 15/53 (28%), Positives = 25/53 (47%)
 Frame = +1

Query: 369 RALYDYAGQEADELSFRAGEELLKMSEEDEQGWCQGQLQSGRIGLYPANYVEC 421
           RALY +       +     EE+  + E+   GW + +   G  G  P++YV+C
Sbjct: 100 RALYPFEAMNEGSVPMGENEEMQILEEDQGDGWTRVRKADGSEGFVPSSYVQC 258
>31183
          Length = 923

 Score = 28.9 bits (63), Expect = 4.0,   Method: Compositional matrix adjust.
 Identities = 13/33 (39%), Positives = 21/33 (63%)
 Frame = +1

Query: 388 EELLKMSEEDEQGWCQGQLQSGRIGLYPANYVE 420
           ++++   E  + GW +G    G+ GL+PANYVE
Sbjct: 1   DDVITDIEMIDDGWWRGSCH-GKNGLFPANYVE 96
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31560792|ref|NP_062408.2| SH3-domain GRB2-like 2 [Mus
musculus]
         (352 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

17286                                                                 100   8e-22
16716                                                                  60   1e-09
12324                                                                  54   7e-08
26032                                                                  54   1e-07
28095                                                                  46   2e-05
15115                                                                  44   9e-05
20131                                                                  44   1e-04
31183                                                                  43   2e-04
13664                                                                  40   0.002
19469                                                                  39   0.003
29687                                                                  39   0.003
13641                                                                  39   0.004
01494                                                                  38   0.006
08480                                                                  35   0.049
18050                                                                  34   0.088
27252                                                                  33   0.15 
29636                                                                  31   0.69 
30740                                                                  30   1.3  
05206                                                                  28   4.1  
26037                                                                  28   5.9  
>17286
          Length = 489

 Score =  100 bits (249), Expect = 8e-22,   Method: Compositional matrix adjust.
 Identities = 40/65 (61%), Positives = 55/65 (84%)
 Frame = +3

Query: 286 PGVQMDQPCCRALYDFEPENEGELGFKEGDIITLTNQIDENWYEGMLHGQSGFFPINYVE 345
           P   + QPC RA+YDF PE++GELGF+EGD+ITL +Q+DENW+EG +HG+ G+FPINYVE
Sbjct: 3   PTAGVKQPCARAIYDFLPESDGELGFQEGDMITLISQVDENWFEGSVHGKVGYFPINYVE 182

Query: 346 ILVAL 350
           ++V +
Sbjct: 183 VVVPI 197
>16716
          Length = 934

 Score = 60.5 bits (145), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 24/55 (43%), Positives = 34/55 (61%)
 Frame = -1

Query: 297 ALYDFEPENEGELGFKEGDIITLTNQIDENWYEGMLHGQSGFFPINYVEILVALP 351
           ALYD++  ++ EL F   D+IT    ID+ W+ G  HG++G FP NYVE+    P
Sbjct: 457 ALYDYQAADDDELTFDPDDVITDIEMIDDGWWRGSCHGKNGLFPANYVELQQ*FP 293
>12324
          Length = 946

 Score = 54.3 bits (129), Expect = 7e-08,   Method: Compositional matrix adjust.
 Identities = 22/49 (44%), Positives = 33/49 (67%)
 Frame = +3

Query: 297 ALYDFEPENEGELGFKEGDIITLTNQIDENWYEGMLHGQSGFFPINYVE 345
           A+YD+E E + EL F E  +I +  + D+ W+EG++ G +G FP NYVE
Sbjct: 702 AIYDYEAEKDDELTFSENSVIYVIRKNDDGWWEGVMDGVTGLFPSNYVE 848
>26032
          Length = 465

 Score = 53.5 bits (127), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 25/52 (48%), Positives = 36/52 (69%)
 Frame = +2

Query: 296 RALYDFEPENEGELGFKEGDIITLTNQIDENWYEGMLHGQSGFFPINYVEIL 347
           R   DFE  ++ ELGF++ DIITL +Q DE+ + G L+G  G+FP  +VE+L
Sbjct: 17  RLF*DFERHDDDELGFRKNDIITLISQKDEHCWIGELNGLRGWFPAKFVEVL 172
>28095
          Length = 597

 Score = 46.2 bits (108), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 20/53 (37%), Positives = 29/53 (54%), Gaps = 2/53 (3%)
 Frame = +3

Query: 295 CRALYDFEPENEGELGFKEGDIITLTNQIDENWYEGMLH--GQSGFFPINYVE 345
           C+A+YD++  +  E+ F +GD I     +D  W  G +   GQ G  P NYVE
Sbjct: 264 CKAMYDYQAADSDEVSFNDGDTIIECQPVDAGWMTGRVERTGQYGMLPSNYVE 422
>15115
          Length = 443

 Score = 43.9 bits (102), Expect = 9e-05,   Method: Compositional matrix adjust.
 Identities = 21/44 (47%), Positives = 28/44 (63%), Gaps = 1/44 (2%)
 Frame = -2

Query: 305 NEGELGFKEGDIITLTNQIDENWYEGML-HGQSGFFPINYVEIL 347
           ++ E+ F   DIIT  +QIDE W++G    G  G FP NYVE+L
Sbjct: 421 DDTEITFDPDDIITNIDQIDEGWWQGFAPDGSYGMFPANYVELL 290
>20131
          Length = 574

 Score = 43.9 bits (102), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 19/49 (38%), Positives = 30/49 (61%)
 Frame = -2

Query: 297 ALYDFEPENEGELGFKEGDIITLTNQIDENWYEGMLHGQSGFFPINYVE 345
           A+Y +      +L F EGD+I +T + DE+W+ G L  ++G FP  YV+
Sbjct: 468 AMYSYVSGETADLTFNEGDMILVTKK-DEDWWTGTLGEKTGMFPSTYVK 325
>31183
          Length = 923

 Score = 42.7 bits (99), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 16/32 (50%), Positives = 22/32 (68%)
 Frame = +1

Query: 315 DIITLTNQIDENWYEGMLHGQSGFFPINYVEI 346
           D+IT    ID+ W+ G  HG++G FP NYVE+
Sbjct: 4   DVITDIEMIDDGWWRGSCHGKNGLFPANYVEL 99
>13664
          Length = 507

 Score = 39.7 bits (91), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 18/43 (41%), Positives = 27/43 (62%), Gaps = 1/43 (2%)
 Frame = +2

Query: 297 ALYDFEPENEGELGFKEGDIITLTNQIDENWYEG-MLHGQSGF 338
           ALYD++ +   EL    GD+I L ++  E+W+ G +L GQ GF
Sbjct: 377 ALYDYKAQRSDELTILSGDVIMLLHKDSESWWMGELLDGQQGF 505
>19469
          Length = 428

 Score = 38.9 bits (89), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 21/58 (36%), Positives = 31/58 (53%), Gaps = 3/58 (5%)
 Frame = -1

Query: 296 RALYDFEPENEGELGFKEGDIITLTNQID---ENWYEGMLHGQSGFFPINYVEILVAL 350
           +ALYD   E   EL F+ GD+IT+  Q     + W+   L G+ G  P N ++IL  +
Sbjct: 356 KALYDNIAETPDELAFRRGDVITILEQDTAGLDGWWLCSLRGRQGIAPGNRLKILSGM 183
>29687
          Length = 434

 Score = 38.9 bits (89), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 20/51 (39%), Positives = 30/51 (58%), Gaps = 1/51 (1%)
 Frame = -2

Query: 296 RALYDFEPENEGELGFKEGDIITLTNQIDENWYEGMLHGQS-GFFPINYVE 345
           +AL+D+  + E EL F +G IIT  ++ D  W+ G    +   +FP NYVE
Sbjct: 289 KALHDYNAKREDELSFCKGAIITNVSRQDGGWWRGDYGTKKQHWFPSNYVE 137
>13641
          Length = 2081

 Score = 38.5 bits (88), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 22/83 (26%), Positives = 40/83 (48%), Gaps = 13/83 (15%)
 Frame = +2

Query: 271 TQPNGGLSHTGTP--KPPGVQMDQPCCRALYDFE-------PENEGELGFKEGDIITLTN 321
           ++ +G L+    P  + PG +  +   +A++ F        P  E  L F++GDI+ + N
Sbjct: 80  SKTSGSLTLKLVPSRRTPGSKKREMVVKAMFSFNSKLDDNIPCKEAGLSFQQGDILHIVN 259

Query: 322 QIDENWYEGMLHG----QSGFFP 340
           Q D  W++   HG    ++G  P
Sbjct: 260 QEDAIWWQAYKHGDAKKRAGLIP 328
>01494
          Length = 2122

 Score = 38.1 bits (87), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 18/51 (35%), Positives = 29/51 (56%), Gaps = 1/51 (1%)
 Frame = +3

Query: 296 RALYDFEPENEGELGFKEGDIITLTNQIDENWYEGMLHGQS-GFFPINYVE 345
           +AL+D+    + EL F +G IIT  ++ D  W+ G    +   +FP N+VE
Sbjct: 315 KALHDYNANRDDELSFCKGAIITNVSRQDGGWWRGDYGAKKQHWFPSNFVE 467
>08480
          Length = 698

 Score = 35.0 bits (79), Expect = 0.049,   Method: Compositional matrix adjust.
 Identities = 15/40 (37%), Positives = 23/40 (57%), Gaps = 5/40 (12%)
 Frame = -1

Query: 295 CRALYDFEPENEGEL-----GFKEGDIITLTNQIDENWYE 329
            RAL+D+EP  +  L      F  GDI+ +TN  D+ W++
Sbjct: 446 VRALFDYEPSKDSGLPSRGLWFHYGDILHVTNASDDEWWQ 327
>18050
          Length = 448

 Score = 34.3 bits (77), Expect = 0.088,   Method: Compositional matrix adjust.
 Identities = 17/60 (28%), Positives = 32/60 (53%), Gaps = 2/60 (3%)
 Frame = +3

Query: 290 MDQPCCRALYDFEPENEGELGFKEGDIITLTNQIDENWYEG--MLHGQSGFFPINYVEIL 347
            D P   A + +E +    L  + GD++ ++ ++ + WY+G  +  G  G+FP +Y E L
Sbjct: 9   WDCPQVIAKHSYESDEPDVLQLELGDVVNVSRKLPDGWYQGERIRDGAVGWFPGSYTEEL 188
>27252
          Length = 378

 Score = 33.5 bits (75), Expect = 0.15,   Method: Compositional matrix adjust.
 Identities = 20/57 (35%), Positives = 30/57 (52%), Gaps = 3/57 (5%)
 Frame = +2

Query: 294 CCRALYDFEPE--NEGELGFKEGDII-TLTNQIDENWYEGMLHGQSGFFPINYVEIL 347
             R + D  P   +  +L  K+G+ I  L   ID  W EG ++G++G FP  +VE L
Sbjct: 122 LARVILDRTPSAYDRTQLKLKQGETIKVLAINIDGQW-EGEINGRTGKFPFTHVEFL 289
>29636
          Length = 354

 Score = 31.2 bits (69), Expect = 0.69,   Method: Compositional matrix adjust.
 Identities = 18/57 (31%), Positives = 30/57 (52%), Gaps = 12/57 (21%)
 Frame = +1

Query: 296 RALYDFEPENEG-----ELG--FKEGDIITLTNQIDENWYEGMLHGQ-----SGFFP 340
           RAL++++PE++      ELG  F +GDI+      D NW++    G+     +G  P
Sbjct: 79  RALFNYDPEDDPYIPCRELGISFLKGDILHAIQLSDSNWWQAHREGEDAHMLAGLIP 249
>30740
          Length = 488

 Score = 30.0 bits (66), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 15/45 (33%), Positives = 26/45 (57%), Gaps = 1/45 (2%)
 Frame = +2

Query: 299 YDFEPENEGELGFKEGDIITLTNQIDENWYEGM-LHGQSGFFPIN 342
           YDF   +  +L F +GDI+ L ++ +E W+     HG+ G  P++
Sbjct: 203 YDFSGRDPEDLPFSKGDILELISKDEEEWWTARDKHGRVGQDPLS 337
>05206
          Length = 1075

 Score = 28.5 bits (62), Expect = 4.1,   Method: Compositional matrix adjust.
 Identities = 19/57 (33%), Positives = 29/57 (50%), Gaps = 5/57 (8%)
 Frame = +1

Query: 295 CRALYDFEPENEGELGFKEGDIITLTNQIDENWYEGMLH-----GQSGFFPINYVEI 346
           CRALY FE  NEG +   E + + +   ++E+  +G        G  GF P +YV+ 
Sbjct: 97  CRALYPFEAMNEGSVPMGENEEMQI---LEEDQGDGWTRVRKADGSEGFVPSSYVQC 258
>26037
          Length = 439

 Score = 28.1 bits (61), Expect = 5.9,   Method: Compositional matrix adjust.
 Identities = 26/71 (36%), Positives = 30/71 (42%), Gaps = 15/71 (21%)
 Frame = +3

Query: 80  QEKGPGYPQAEALLAEAMLKFG-------------RELGDD-C-NFGPALGEVGEAMREL 124
           Q K     QAEA LAE+  KFG             +E  D  C      L E  +AM EL
Sbjct: 120 QAKSTSLEQAEAKLAESTEKFGQLKAEAKTKISGLKEKYDQLCEKHKEELSEKDKAMEEL 299

Query: 125 SEVKDSLDMEV 135
           S  KDS+   V
Sbjct: 300 SREKDSMAASV 332
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|167234411|ref|NP_084036.2| nucleotide binding
protein-like [Mus musculus]
         (319 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

33369                                                                 100   1e-21
>33369
          Length = 830

 Score = 99.8 bits (247), Expect = 1e-21,   Method: Compositional matrix adjust.
 Identities = 45/92 (48%), Positives = 64/92 (69%)
 Frame = -3

Query: 222 AEMFRKVNVPVLGLVQNMSVFQCPKCKHKTHIFGADGARKLAQTLDLDVLGDVPLHLSIR 281
           A MF KV+VPVLG+++NMSVF CP C H  HIFG  GA+KLAQ   + +LG++PL   I 
Sbjct: 828 AAMFSKVDVPVLGVIENMSVFLCPNCGHAHHIFGQKGAQKLAQETGIHILGEIPLDGRIC 649

Query: 282 EASDMGQPVVFSQPGSDEAKAYLHIASEVVRR 313
           E SD GQP++ ++P S +A  + +IA ++  +
Sbjct: 648 ELSDAGQPIMVAEPESPQAAVFKNIAKKIXEK 553
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|29336026|ref|NP_082297.1| myosin, heavy polypeptide
14 [Mus musculus]
         (1992 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

25922                                                                 103   1e-21
01284                                                                  84   5e-16
31878                                                                  55   1e-12
25944                                                                  50   1e-05
01074                                                                  35   0.45 
20566                                                                  32   1.9  
33313                                                                  30   9.6  
>25922
          Length = 422

 Score =  103 bits (256), Expect = 1e-21,   Method: Composition-based stats.
 Identities = 55/133 (41%), Positives = 79/133 (59%)
 Frame = -2

Query: 407 FSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRALDRSPRQG 466
            + AL+   + V  D V    +  ++ +A +AL KA Y R+F WLV R+N ++     Q 
Sbjct: 409 LAHALMHRTVAVKGDMVTTDLSVSESSYARDALCKALYSRMFSWLVHRINDSIKVRGAQR 230

Query: 467 ASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPWTFLDF 526
              +G+LDI GFE+F+ NSFEQ  INY NEKLQQ+F       EQEEY +EGI W  +++
Sbjct: 229 TKVMGVLDIYGFEVFENNSFEQFIINYCNEKLQQIFIELTLKEEQEEYIKEGIEWIHVEY 50

Query: 527 GLDLQPCIDLIER 539
             +   C +LIE+
Sbjct: 49  FNNAVIC-ELIEK 14
>01284
          Length = 1603

 Score = 84.3 bits (207), Expect = 5e-16,   Method: Compositional matrix adjust.
 Identities = 42/131 (32%), Positives = 73/131 (55%)
 Frame = +2

Query: 663 FRTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEGIR 722
           F +VG  +++ L  LM  L +T  +F+RCI PN +      E   +L QL+C G++  + 
Sbjct: 11  FISVGTKFRKQLLVLMDKLKSTGTNFIRCIKPNVKMVDHLFEGANILSQLQCAGMVSVLE 190

Query: 723 ICRQGFPNRILFQEFRQRYEILTPNAIPKGFMDGKQACEKMIQALELDPNLYRVGQSKIF 782
           + +QGFP+R  F E    Y+   P  + +  +D +  C+ + +AL LD   ++ G +K+F
Sbjct: 191 LMQQGFPSRTPFSELYNMYKKYLPPELSR--LDPRLFCKSLFKALGLDDKDFKFGLTKVF 364

Query: 783 FRAGVLAQLEE 793
           FR G  A+ ++
Sbjct: 365 FRPGKFAEFDQ 397
>31878
          Length = 1178

 Score = 55.1 bits (131), Expect(2) = 1e-12,   Method: Compositional matrix adjust.
 Identities = 21/41 (51%), Positives = 32/41 (78%), Gaps = 1/41 (2%)
 Frame = -1

Query: 832  MQRNCAAYLKLRNWQWWRLFIKVKPLLQVTR-QDEVLQARA 871
            +QRN   Y+K+R W WW+L+ KVKP+L V R ++E+L+A+A
Sbjct: 1043 IQRNVQKYMKIREWSWWKLYTKVKPILNVHRTEEELLEAQA 921

 Score = 38.1 bits (87), Expect(2) = 1e-12,   Method: Compositional matrix adjust.
 Identities = 17/28 (60%), Positives = 20/28 (71%)
 Frame = -2

Query: 787  VLAQLEEERDLKVTDIIVSFQAAARGYL 814
            VL+QLE  RD K+T I+  FQA  RGYL
Sbjct: 1177 VLSQLEAGRDEKLTGIVTQFQALCRGYL 1094
>25944
          Length = 417

 Score = 49.7 bits (117), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 36/124 (29%), Positives = 62/124 (50%)
 Frame = -3

Query: 1575 KLRLEVTVQALKAQHERDLQGRDDAGEERRRQLAKQLRDAEVERDEEXXXXXXXXXXXXX 1634
            KLRLEV + AL+ +++ ++ GR++  EE +R L +QLR+ E E ++E             
Sbjct: 373  KLRLEVNMNALREKYKNEVAGREEQEEESKRSLLRQLREMEAELEDERKQRALAVNARNK 194

Query: 1635 XXXXXXXXXXQTSAAGQGKEEAXXXXXXXXXXXXELWREVEETRSSRDEMFTLSRENEKK 1694
                      Q   A + KE+A            +   E+E+ R +R++M   +++NEKK
Sbjct: 193  LQGDVQGMEQQLEMATKVKEDAVKQYKKIFAQMKDFQHELEDARIAREDMAAQAKDNEKK 14

Query: 1695 LKGL 1698
            +K L
Sbjct: 13   VKNL 2
>01074
          Length = 2584

 Score = 34.7 bits (78), Expect = 0.45,   Method: Compositional matrix adjust.
 Identities = 22/70 (31%), Positives = 33/70 (47%)
 Frame = -2

Query: 1869 LQVDEERRVADQVRDQLEKSNLRXXXXXXXXXXXXXXXXXXXXXXXXLQRELEDVTESAE 1928
            +Q ++ERR ADQ ++QL+K N R                        +QREL+D  E  +
Sbjct: 2343 IQAEDERRSADQYKEQLDKMNNRVKALKRQVDEAEEECARINAQKRKVQRELDDQMEQND 2164

Query: 1929 SMNREVTTLR 1938
             + RE  +LR
Sbjct: 2163 VLVRETQSLR 2134
>20566
          Length = 911

 Score = 32.3 bits (72), Expect = 1.9,   Method: Compositional matrix adjust.
 Identities = 22/84 (26%), Positives = 41/84 (48%)
 Frame = +3

Query: 1855 KLVRRAEKRLKEVVLQVDEERRVADQVRDQLEKSNLRXXXXXXXXXXXXXXXXXXXXXXX 1914
            K +R+A++RLKE+  Q DE+R+  ++++D ++K   +                       
Sbjct: 288  KNMRKADRRLKELAFQSDEDRKNQERIQDLVDKLQAKIKTYKRQVEEAEEIAAVNLAKFR 467

Query: 1915 XLQRELEDVTESAESMNREVTTLR 1938
             +Q ELED  E A++    ++ LR
Sbjct: 468  KVQNELEDAEERADTAEGTLSKLR 539
>33313
          Length = 566

 Score = 30.0 bits (66), Expect = 9.6,   Method: Composition-based stats.
 Identities = 11/25 (44%), Positives = 19/25 (76%)
 Frame = -3

Query: 1916 LQRELEDVTESAESMNREVTTLRNR 1940
            L+ E+E+ T+SAE + RE+ + RN+
Sbjct: 306  LKEEMEEATQSAEEIRREIQSFRNK 232
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6754208|ref|NP_034569.1| high mobility group box 1
[Mus musculus]
         (215 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

11933                                                                  99   1e-21
33187                                                                  81   3e-16
14405                                                                  48   3e-06
24607                                                                  48   4e-06
21088                                                                  31   0.38 
04411                                                                  28   3.5  
>11933
          Length = 1516

 Score = 99.4 bits (246), Expect = 1e-21,   Method: Compositional matrix adjust.
 Identities = 57/159 (35%), Positives = 86/159 (54%)
 Frame = +2

Query: 5   DPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMA 64
           D  KP+   S+Y +F+  CRE   K+    S   +EF+K+CS +W+ M   +K  FE+ A
Sbjct: 632 DANKPKRSTSAYXYFLAHCREVSAKQGKTIS-RIAEFTKECSAKWREMGGAQKKPFEESA 808

Query: 65  KADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGD 124
             DKARY++EM  Y       K K  DPN PKRP +A+FLF  ++R K+K  + G+   +
Sbjct: 809 AKDKARYDKEMALY-------KGKSTDPNKPKRPMTAYFLFLGDFRIKMK--NRGVDHKE 961

Query: 125 VAKKLGEMWNNTAADDKQPXXXXXXXXXXXXXXDIAAYR 163
           + +  GE W N +A+DK+P              ++  YR
Sbjct: 962 ILRLAGEEWRNMSAEDKKPYEKRSVEAGKKYEVEMEEYR 1078

 Score = 37.0 bits (84), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 24/79 (30%), Positives = 40/79 (50%)
 Frame = +2

Query: 5   DPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMA 64
           DP KP+  M++Y  F+   R + K +     V+  E  +   E W+ MSA++K  +E  +
Sbjct: 866 DPNKPKRPMTAYFLFLGDFRIKMKNR----GVDHKEILRLAGEEWRNMSAEDKKPYEKRS 1033

Query: 65  KADKARYEREMKTYIPPKG 83
                +YE EM+ Y   +G
Sbjct: 1034VEAGKKYEVEMEEYRKNEG 1090

 Score = 28.1 bits (61), Expect = 2.6,   Method: Compositional matrix adjust.
 Identities = 19/80 (23%), Positives = 31/80 (38%), Gaps = 1/80 (1%)
 Frame = +2

Query: 87  KKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLS-IGDVAKKLGEMWNNTAADDKQPXX 145
           ++ KD N PKR  SA+  F +  R     +   +S I +  K+    W       K+P  
Sbjct: 620 QEVKDANKPKRSTSAYXYFLAHCREVSAKQGKTISRIAEFTKECSAKWREMGGAQKKPFE 799

Query: 146 XXXXXXXXXXXXDIAAYRAK 165
                       ++A Y+ K
Sbjct: 800 ESAAKDKARYDKEMALYKGK 859
>33187
          Length = 644

 Score = 81.3 bits (199), Expect = 3e-16,   Method: Compositional matrix adjust.
 Identities = 40/103 (38%), Positives = 58/103 (56%), Gaps = 6/103 (5%)
 Frame = +3

Query: 71  YEREMKTYIPPKGET------KKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGD 124
           YE+EM+ Y+PPKG        +K+ KDPNAPKR  SAFF FC++ R K+K  +P   +GD
Sbjct: 6   YEQEMQNYVPPKGTVVGRGKKRKQIKDPNAPKRSLSAFFWFCNDERNKVKALNPEFGVGD 185

Query: 125 VAKKLGEMWNNTAADDKQPXXXXXXXXXXXXXXDIAAYRAKGK 167
           +AK+LG  W++   + KQ               ++  Y+  GK
Sbjct: 186 IAKELGRKWSDVDPEVKQKYESMAERDKARYEREMTEYKTSGK 314

 Score = 48.5 bits (114), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 26/74 (35%), Positives = 42/74 (56%)
 Frame = +3

Query: 5   DPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMA 64
           DP  P+  +S++ +F    R + K  +P+  V   + +K+   +W  +  + K K+E MA
Sbjct: 84  DPNAPKRSLSAFFWFCNDERNKVKALNPEFGV--GDIAKELGRKWSDVDPEVKQKYESMA 257

Query: 65  KADKARYEREMKTY 78
           + DKARYEREM  Y
Sbjct: 258 ERDKARYEREMTEY 299
>14405
          Length = 600

 Score = 48.1 bits (113), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 15/39 (38%), Positives = 25/39 (64%)
 Frame = -2

Query: 96  KRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWN 134
           +R P+A+ L+C+  RPK+  E PG+    +++ LG MW 
Sbjct: 254 RRAPTAYMLYCNSQRPKVVAESPGIDFAQISRTLGVMWQ 138
>24607
          Length = 1354

 Score = 47.8 bits (112), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 17/54 (31%), Positives = 30/54 (55%)
 Frame = -2

Query: 88  KFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDK 141
           + K     +R P+A+ L+C+  RPK+  E PG+    +++ LG MW   +  +K
Sbjct: 417 RIKRKGPSRRAPTAYMLYCNSQRPKVVAESPGIDFAQISRTLGVMWQCLSKKEK 256
>21088
          Length = 490

 Score = 30.8 bits (68), Expect = 0.38,   Method: Compositional matrix adjust.
 Identities = 14/44 (31%), Positives = 22/44 (50%)
 Frame = -3

Query: 93  NAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNT 136
            A KRP +AF +F    R ++    P L    ++K LG++W   
Sbjct: 335 GAVKRPMNAFMVFAKMERRQMMAAQPELHNARISKHLGDVWRQC 204
>04411
          Length = 1247

 Score = 27.7 bits (60), Expect = 3.5,   Method: Compositional matrix adjust.
 Identities = 8/42 (19%), Positives = 22/42 (52%)
 Frame = +1

Query: 37  NFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTY 78
           N++ + K C + W+++ A ++   E + + D   +   ++ Y
Sbjct: 148 NYTFYDKSCGKIWQSIEALDRAGMEIIERMDPVSFTNYLREY 273
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|148747585|ref|NP_001034773.2| Meckel syndrome, type 1
[Mus musculus]
         (561 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

21016                                                                 100   2e-21
>21016
          Length = 499

 Score =  100 bits (249), Expect = 2e-21,   Method: Compositional matrix adjust.
 Identities = 52/140 (37%), Positives = 80/140 (57%), Gaps = 4/140 (2%)
 Frame = -2

Query: 77  VIGWQEKLFSQFEVDLYQNESACQSPLDHQYRQEILKLENSGGRKNRRIFTYTDSDRYTD 136
           V  WQEK++SQ EV++Y  +  C   L+ +Y +E+  +  + GR   R+F++ D D Y+ 
Sbjct: 417 VFLWQEKVYSQREVEMYSKQENCSXILEQKYNEEVAAI-VAKGRPTNRLFSFVDHDPYSH 241

Query: 137 LEEYCQKITTSASEVPSFLAERMANVXXXXXXXXGVEGSKL----KSRIVTWEPSEDFIK 192
            +E    +TTS  E PS LAE+MA+V         ++  ++    K+ IV  EP+ED + 
Sbjct: 240 QDETVHYMTTSXKEKPSVLAEKMAHVRCRRVGGRQLKEKEMGIIPKTNIVELEPTEDMVN 61

Query: 193 NNHAINTPLQTMYIMADLGP 212
            +H    P+Q MYIMADL P
Sbjct: 60  KSHIEPPPMQVMYIMADLSP 1
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|23956076|ref|NP_038879.1| ATP-binding cassette,
sub-family A (ABC1), member 8b [Mus musculus]
         (1620 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

26534                                                                 102   2e-21
27295                                                                  72   6e-17
01623                                                                  69   2e-11
05764                                                                  68   3e-11
20400                                                                  60   1e-08
02301                                                                  47   4e-05
30281                                                                  43   0.001
03538                                                                  39   0.014
29130                                                                  39   0.020
20290                                                                  37   0.048
38795                                                                  33   0.97 
09986                                                                  33   1.1  
18248                                                                  32   1.9  
>26534
          Length = 931

 Score =  102 bits (253), Expect = 2e-21,   Method: Compositional matrix adjust.
 Identities = 52/132 (39%), Positives = 82/132 (62%), Gaps = 1/132 (0%)
 Frame = +1

Query: 667 VLFSTQFMDEADILADRKVFISNGRLKCAGSSLFLKKKWGVGYHLSLQLKEVCVPENITS 726
           +L ST FMDEAD+L DR   ++ G +KC G+S+FLKK +G GYH+ +     C    +T+
Sbjct: 13  LLLSTHFMDEADLLGDRIAIMAEGVVKCCGTSMFLKKLYGAGYHMVMVKGPQCDVATVTA 192

Query: 727 LVKQHIPAAKLSAEGEGKLLYTLPLETTYRFPELCQSLDS-CPGLGIENYGVSMTTLNEV 785
            V+  +P A+L +E   +L + LP E   +F +L + ++S    LGI ++G + TT+ EV
Sbjct: 193 AVQAQLPGAQLESEIGAELSFLLPEEEAPKFADLFRVMESQSDELGITSFGATATTMEEV 372

Query: 786 FLKLEGKASIDE 797
           FLK+ G + + E
Sbjct: 373 FLKV-GASGVSE 405

 Score = 62.0 bits (149), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 33/123 (26%), Positives = 60/123 (48%)
 Frame = +1

Query: 1470 LLTTHYMAEAEALCDRVAILVSGRLRCIGSIQHLKSKFGKDYLLEMKVKTLEQVEPLNTE 1529
            LL+TH+M EA+ L DR+AI+  G ++C G+   LK  +G  Y + M       V  +   
Sbjct: 16   LLSTHFMDEADLLGDRIAIMAEGVVKCCGTSMFLKKLYGAGYHMVMVKGPQCDVATVTAA 195

Query: 1530 ILRLFPQASRQERYSSLMAYKLPVEAVQPLSQAFFKLEKVKQTFDLEEYSLSQSTLEQVF 1589
            +    P A  +    + +++ LP E     +  F  +E       +  +  + +T+E+VF
Sbjct: 196  VQAQLPGAQLESEIGAELSFLLPEEEAPKFADLFRVMESQSDELGITSFGATATTMEEVF 375

Query: 1590 LEL 1592
            L++
Sbjct: 376  LKV 384
>27295
          Length = 384

 Score = 72.4 bits (176), Expect(3) = 6e-17,   Method: Compositional matrix adjust.
 Identities = 36/103 (34%), Positives = 62/103 (60%)
 Frame = +1

Query: 519 AGKSTLLNILSGLSVPTKGSVTIYNNNLSEMADLENILRIAGVCPQANVQFDFLTVRENL 578
            GK+T +++L+G   PT G  T + N      D+ N+    G+CPQ N+ FD LTV E+L
Sbjct: 1   GGKTTTMSMLTGFIPPTSG--TAFVNGYDIRTDINNVRSNLGLCPQHNILFDTLTVDEHL 174

Query: 579 RLFAKIRGIPPQDVEKEVQRVLLELEMKNIQNILAQNLSGGQK 621
           + FA+++G P  ++   V  +  E+++++ ++ LA  LSGG +
Sbjct: 175 QFFARLKGCPRDEIPGAVAEMAKEVDLESKRSALAGTLSGGTE 303

 Score = 31.6 bits (70), Expect(3) = 6e-17,   Method: Compositional matrix adjust.
 Identities = 13/21 (61%), Positives = 18/21 (85%)
 Frame = +2

Query: 618 GGQKRKLTFGIAILGDSQIFL 638
           GGQKRKL+ GIA++G S+I +
Sbjct: 293 GGQKRKLSVGIALIGGSKIVI 355

 Score = 23.1 bits (48), Expect(3) = 6e-17,   Method: Composition-based stats.
 Identities = 9/17 (52%), Positives = 13/17 (76%)
 Frame = +3

Query: 631 LGDSQIFLLDEPTAGLD 647
           L D ++  LDEPT+G+D
Sbjct: 333 LVDPRL*YLDEPTSGMD 383

 Score = 55.8 bits (133), Expect(2) = 2e-08,   Method: Compositional matrix adjust.
 Identities = 31/101 (30%), Positives = 52/101 (51%), Gaps = 4/101 (3%)
 Frame = +1

Query: 1325 AGKSTSLKMISGDTKVTAGQVLLKG----SREGDTPGFLGYCPQENALWPNLTVKEHLEI 1380
             GK+T++ M++G    T+G   + G    +   +    LG CPQ N L+  LTV EHL+ 
Sbjct: 1    GGKTTTMSMLTGFIPPTSGTAFVNGYDIRTDINNVRSNLGLCPQHNILFDTLTVDEHLQF 180

Query: 1381 FAAVRGLRKSHAAVAITRLADALKLQDQLKSPVKTLSEGVK 1421
            FA ++G  +     A+  +A  + L+ +  +   TLS G +
Sbjct: 181  FARLKGCPRDEIPGAVAEMAKEVDLESKRSALAGTLSGGTE 303

 Score = 22.7 bits (47), Expect(2) = 2e-08,   Method: Composition-based stats.
 Identities = 8/17 (47%), Positives = 13/17 (76%)
 Frame = +3

Query: 1431 LGNPSILLLDEPSTGLD 1447
            L +P +  LDEP++G+D
Sbjct: 333  LVDPRL*YLDEPTSGMD 383
>01623
          Length = 1414

 Score = 68.6 bits (166), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 57/199 (28%), Positives = 93/199 (46%), Gaps = 8/199 (4%)
 Frame = +3

Query: 478 SIRIRNISKEYKGKPNKIEALKDLTLDIYEGQITAVLGHSGAGKSTLLNILSGLSVPTKG 537
           +I  R+I   Y G+P+ +   K   L    GQ+TAV+G SG+GKST+  +L     P  G
Sbjct: 24  NIEFRDIHFAYPGRPD-VAIFKGFNLQARAGQVTAVVGPSGSGKSTVCGLLLRYYDPNAG 200

Query: 538 SVTIYNNNLSEMADLENILRIAGVCPQANVQFDFLTVRENLRLFA-KIRGIPPQDVEKEV 596
            V +   N++E+ D   +    G   Q  + F   +V EN+   A     +    +E   
Sbjct: 201 QVMLDGQNIAEL-DPTWLRSHIGTVSQEPILFS-CSVAENIAYGAVNPDAVTLGQIEDAA 374

Query: 597 QRV-------LLELEMKNIQNILAQNLSGGQKRKLTFGIAILGDSQIFLLDEPTAGLDPF 649
           ++           L +  +       LSGGQ++++    AIL + +I LLDE T+ LD  
Sbjct: 375 RKANAFNFVSTFPLGLDTMVGERGMMLSGGQRQRIAIARAILKNPEILLLDEATSALDAE 554

Query: 650 SRHRVWNLLKERRADRVVL 668
           S + V + L++    R V+
Sbjct: 555 SEYLVQDALEKLMGGRTVI 611

 Score = 48.9 bits (115), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 55/212 (25%), Positives = 94/212 (44%), Gaps = 19/212 (8%)
 Frame = +3

Query: 1311 VRKGEILGLLGHNGAGKSTSLKMISGDTKVTAGQVLLKGSREGD-TPGFL----GYCPQE 1365
             R G++  ++G +G+GKST   ++       AGQV+L G    +  P +L    G   QE
Sbjct: 102  ARAGQVTAVVGPSGSGKSTVCGLLLRYYDPNAGQVMLDGQNIAELDPTWLRSHIGTVSQE 281

Query: 1366 NALWPNLTVKEHLEIFAAVRGLRKSHAAVAITRLADA--------------LKLQDQLKS 1411
              L+ + +V E++  + AV     +  AV + ++ DA              L L   +  
Sbjct: 282  PILF-SCSVAENIA-YGAV-----NPDAVTLGQIEDAARKANAFNFVSTFPLGLDTMVGE 440

Query: 1412 PVKTLSEGVKRKLCFVLSILGNPSILLLDEPSTGLDPEGXXXXXXXXXXXXKNTDRGALL 1471
                LS G ++++    +IL NP ILLLDE ++ LD E                 R  + 
Sbjct: 441  RGMMLSGGQRQRIAIARAILKNPEILLLDEATSALDAESEYLVQDALEKLMGG--RTVIT 614

Query: 1472 TTHYMAEAEALCDRVAILVSGRLRCIGSIQHL 1503
              H ++  +   +++A+L  G +  +GS Q L
Sbjct: 615  IAHRLSTIKT-ANQIAVLTDGVVAEMGSYQDL 707
>05764
          Length = 1395

 Score = 68.2 bits (165), Expect = 3e-11,   Method: Compositional matrix adjust.
 Identities = 57/222 (25%), Positives = 106/222 (47%), Gaps = 17/222 (7%)
 Frame = -2

Query: 476  KESIRIRNISKEYKGKPNKIEALKDLTLDIYEGQITAVLGHSGAGKSTLLNILSGLSVPT 535
            K +I++  +   Y  +P +I+ LK ++L+I  GQ  A++G SG GKST++++L     P+
Sbjct: 1142 KGNIKVEKVEFCYPTRP-EIQVLKGISLEISAGQTAALVGISGCGKSTIISLLQRYYDPS 966

Query: 536  KGSVTIYNNNLSEMADLENILRIAGVCPQANVQFDFLTVRENLRLFAKIRGIPPQDVEKE 595
            KG + +   ++ +  ++  +  +  V  Q  + FD  ++R+N++ +     +P  D    
Sbjct: 965  KGRLLVDGTDVRDY-NITALRSLLSVVSQEPILFD-CSIRDNIQ-YGLESDVPMPD---- 807

Query: 596  VQRVLLELEMKNIQNILAQ--------------NLSGGQKRKLTFGIAILGDSQIFLLDE 641
               ++   +  NI   +A                LSGGQK+++    A++ +  I LLDE
Sbjct: 806  ---IIAACKTANIHEFIASLPQGYDTQVGGKGTQLSGGQKQRVAIARALVRNPIILLLDE 636

Query: 642  PTAGLDPFSRHRVWNLLKERRADR---VVLFSTQFMDEADIL 680
             T+ LD  S   V   L   R  R   V+      +  AD++
Sbjct: 635  ATSALDTESEKLVQAALDNAREGRTCIVIAHRLSTIQNADVI 510

 Score = 39.7 bits (91), Expect = 0.009,   Method: Compositional matrix adjust.
 Identities = 42/188 (22%), Positives = 82/188 (43%), Gaps = 21/188 (11%)
 Frame = -2

Query: 1283 LRKEYAG-----KQKHCLSKKKAKIATRNVSFCVRKGEILGLLGHNGAGKSTSLKMISGD 1337
            +RK+  G     K + C   +      + +S  +  G+   L+G +G GKST + ++   
Sbjct: 1157 IRKDAKGNIKVEKVEFCYPTRPEIQVLKGISLEISAGQTAALVGISGCGKSTIISLLQRY 978

Query: 1338 TKVTAGQVLLKGSREGDTP-----GFLGYCPQENALWPNLTVKEHLE-----------IF 1381
               + G++L+ G+   D         L    QE  L+ + +++++++           I 
Sbjct: 977  YDPSKGRLLVDGTDVRDYNITALRSLLSVVSQEPILF-DCSIRDNIQYGLESDVPMPDII 801

Query: 1382 AAVRGLRKSHAAVAITRLADALKLQDQLKSPVKTLSEGVKRKLCFVLSILGNPSILLLDE 1441
            AA +         ++ +  D      Q+      LS G K+++    +++ NP ILLLDE
Sbjct: 800  AACKTANIHEFIASLPQGYDT-----QVGGKGTQLSGGQKQRVAIARALVRNPIILLLDE 636

Query: 1442 PSTGLDPE 1449
             ++ LD E
Sbjct: 635  ATSALDTE 612
>20400
          Length = 409

 Score = 59.7 bits (143), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 35/88 (39%), Positives = 53/88 (60%), Gaps = 6/88 (6%)
 Frame = -3

Query: 716 KEVCVP---ENITSLVKQHIPAAKLSAEGEGKLLYTLPLETTYR--FPELCQSLD-SCPG 769
           K+ C P   E ++  +++H+P+A L+A+G+ +L Y LP E   +  F +L Q LD S P 
Sbjct: 278 KQACSPCSVEAVSKFIQKHVPSAYLAADGQRELQYILPFEEAKKGNFRKLFQGLDASLPD 99

Query: 770 LGIENYGVSMTTLNEVFLKLEGKASIDE 797
           L I +YGV  T L E+FLK+   A  +E
Sbjct: 98  LHINSYGVMDTNLEEIFLKITEAACQEE 15
>02301
          Length = 1098

 Score = 47.4 bits (111), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 34/99 (34%), Positives = 49/99 (49%)
 Frame = -2

Query: 616 LSGGQKRKLTFGIAILGDSQIFLLDEPTAGLDPFSRHRVWNLLKERRADRVVLFSTQFMD 675
           LSGGQK++L    A++    I LLDE T+ LD  S   V + + E    R V+     + 
Sbjct: 686 LSGGQKQRLAIARALVRQPAILLLDEATSALDTQSESLVQSAINECTRGRTVVIIAHRLT 507

Query: 676 EADILADRKVFISNGRLKCAGSSLFLKKKWGVGYHLSLQ 714
             +  ADR + I+ GR+   GS   L K  G+   L+ Q
Sbjct: 506 TVE-KADRVLVINKGRVVEEGSPSHLLKLGGMFTSLARQ 393

 Score = 39.3 bits (90), Expect = 0.014,   Method: Compositional matrix adjust.
 Identities = 26/88 (29%), Positives = 42/88 (47%)
 Frame = -2

Query: 1416 LSEGVKRKLCFVLSILGNPSILLLDEPSTGLDPEGXXXXXXXXXXXXKNTDRGALLTTHY 1475
            LS G K++L    +++  P+ILLLDE ++ LD +             +   R  ++  H 
Sbjct: 686  LSGGQKQRLAIARALVRQPAILLLDEATSALDTQSESLVQSAINECTRG--RTVVIIAHR 513

Query: 1476 MAEAEALCDRVAILVSGRLRCIGSIQHL 1503
            +   E   DRV ++  GR+   GS  HL
Sbjct: 512  LTTVEK-ADRVLVINKGRVVEEGSPSHL 432
>30281
          Length = 821

 Score = 42.7 bits (99), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 35/96 (36%), Positives = 56/96 (58%), Gaps = 5/96 (5%)
 Frame = -2

Query: 557 RIAGVCPQANVQFDFLTVRENLRLFAK--IRGIPPQDVEK-EVQRVLLELEMKNIQNILA 613
           RIA V  QA +Q    TVR+N+ LF    IR      +E+ E++R +  L   ++  I  
Sbjct: 817 RIAYVPQQAWIQN--ATVRDNI-LFGSPYIRSKYKAILEQCELERDVAMLPGGDLTQIGE 647

Query: 614 Q--NLSGGQKRKLTFGIAILGDSQIFLLDEPTAGLD 647
           +  NLSGGQK++++   A+  DS ++LLD+P + +D
Sbjct: 646 KGINLSGGQKQRVSVARAVYSDSDVYLLDDPLSAVD 539
>03538
          Length = 1974

 Score = 39.3 bits (90), Expect = 0.014,   Method: Composition-based stats.
 Identities = 38/131 (29%), Positives = 60/131 (45%), Gaps = 1/131 (0%)
 Frame = -1

Query: 518  GAGKSTLLNILSGLSVPTKGSVTIYNNNLSEMADLENILRIAGVCPQANVQFDFLTVREN 577
            G GKSTLL +L G   P++G              + + LR+ G   Q +   D L + E+
Sbjct: 1971 GVGKSTLLKLLMGDLQPSQGE-----------KRMNHRLRV-GKYDQHSA--DQLNLDES 1834

Query: 578  -LRLFAKIRGIPPQDVEKEVQRVLLELEMKNIQNILAQNLSGGQKRKLTFGIAILGDSQI 636
             +    ++  +  QD  K + RV L     +   IL ++LSGGQ+ ++           +
Sbjct: 1833 PVEYLKRLFDLQYQDARKMLGRVGLA---SHAHTILNRDLSGGQRARVALAELSCRAPDV 1663

Query: 637  FLLDEPTAGLD 647
             +LDEPT  LD
Sbjct: 1662 LVLDEPTNNLD 1630
>29130
          Length = 436

 Score = 38.5 bits (88), Expect = 0.020,   Method: Composition-based stats.
 Identities = 28/81 (34%), Positives = 42/81 (51%), Gaps = 2/81 (2%)
 Frame = +3

Query: 491 KPNKIEALKDLTLDIYEGQITAVLGHSGAGKSTLLNILSGLSVPTKGSVTIYNNNLSEMA 550
           +P     L+DLT +I  G+   ++G +GAGKS+L   L  L     G++ I + ++S + 
Sbjct: 21  RPGLDLVLRDLTYEINPGEKVGIVGRTGAGKSSLTLALFRLIEAAGGAIIIDDVDVSSLG 200

Query: 551 --DLENILRIAGVCPQANVQF 569
             DL N L I    PQ  V F
Sbjct: 201 LHDLRNKLNI---LPQDPVIF 254
>20290
          Length = 1550

 Score = 37.4 bits (85), Expect = 0.048,   Method: Compositional matrix adjust.
 Identities = 28/97 (28%), Positives = 51/97 (52%), Gaps = 7/97 (7%)
 Frame = +3

Query: 599  VLLELEMKNIQNILAQNLSGGQKRKLTFGIAILGDSQIFLLDEPTAGLDPFSRHRVWNLL 658
            V+  ++++ I +   QNLSGG+ +++   + +   + ++L+DEP+A LD   R     L+
Sbjct: 996  VMKPMKIEEIMDQEVQNLSGGELQRVALVLCLGKPADVYLIDEPSAYLDSEQR-----LV 1160

Query: 659  KERRADRVVLFS--TQFMDEADI-----LADRKVFIS 688
              +   R +L +  T F+ E D      LADR + I 
Sbjct: 1161 AAKVIKRYILHAKKTGFVVEHDFIMATYLADRVIVIE 1271

 Score = 32.3 bits (72), Expect = 1.8,   Method: Compositional matrix adjust.
 Identities = 13/23 (56%), Positives = 19/23 (82%)
 Frame = +1

Query: 1315 EILGLLGHNGAGKSTSLKMISGD 1337
            EIL LLG NG GK+T ++M++G+
Sbjct: 781  EILVLLGENGTGKTTFIRMLAGN 849
>38795
          Length = 792

 Score = 33.1 bits (74), Expect = 0.97,   Method: Compositional matrix adjust.
 Identities = 16/33 (48%), Positives = 23/33 (69%)
 Frame = +1

Query: 1305 RNVSFCVRKGEILGLLGHNGAGKSTSLKMISGD 1337
            +N+ F +     + L+G NGAGKST LK+ISG+
Sbjct: 688  QNLDFGIDLDTRVALVGPNGAGKSTLLKLISGE 786
>09986
          Length = 2844

 Score = 32.7 bits (73), Expect = 1.1,   Method: Composition-based stats.
 Identities = 24/71 (33%), Positives = 35/71 (49%), Gaps = 1/71 (1%)
 Frame = -3

Query: 694  CAGSSLFLKKKWGVGYHLSLQLK-EVCVPENITSLVKQHIPAAKLSAEGEGKLLYTLPLE 752
            C  SS F +K+W   Y  SL L   V  P  +TS+V+QH+ +A ++   +G        E
Sbjct: 1270 CTQSSRFSEKRWSNIYD-SLNLTVRVSSPLTVTSVVQQHL-SATVTPXTQGTSAMAFLFE 1097

Query: 753  TTYRFPELCQS 763
             T + P L  S
Sbjct: 1096 XTGQXPHLSPS 1064
>18248
          Length = 466

 Score = 32.0 bits (71), Expect = 1.9,   Method: Composition-based stats.
 Identities = 12/34 (35%), Positives = 24/34 (70%)
 Frame = +1

Query: 614 QNLSGGQKRKLTFGIAILGDSQIFLLDEPTAGLD 647
           +NLSGG+ +++   + +   + ++L+DEP+A LD
Sbjct: 364 KNLSGGELQRVALTLCLGKPADVYLIDEPSAYLD 465
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|7305307|ref|NP_038893.1| N-myc downstream regulated
gene 3 [Mus musculus]
         (375 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

34081                                                                  99   2e-21
29933                                                                  51   7e-07
>34081
          Length = 315

 Score = 99.4 bits (246), Expect = 2e-21,   Method: Compositional matrix adjust.
 Identities = 47/99 (47%), Positives = 63/99 (63%)
 Frame = +2

Query: 53  NRPVILTYHDIGLNHKSCFNTFFNFEDMQEITQHFAVCHVDAPGQQEAAPSFPTGYQYPT 112
           ++P ILT+HDIGLNH +CF  FF+F DMQ I +HF V HV+APGQ+E+A      + YPT
Sbjct: 8   SKPAILTFHDIGLNHVTCFQGFFSFSDMQPILRHFCVFHVNAPGQEESALYLKPEFVYPT 187

Query: 113 MDELAEMLPPVLTHLSMKSXXXXXXXXXXXXLSRFALNH 151
           MD+LAE +  V+ H  +KS            L+R+ L H
Sbjct: 188 MDQLAEGVHHVVEHYGLKSIIGFGVGAGANVLTRYELAH 304
>29933
          Length = 346

 Score = 51.2 bits (121), Expect = 7e-07,   Method: Composition-based stats.
 Identities = 32/108 (29%), Positives = 50/108 (46%), Gaps = 6/108 (5%)
 Frame = +3

Query: 93  DAPGQQEAAPSFPTGYQYPTMDELAEMLPPVLTHLSMKSXXXXXXXXXXXXLSRFALNHP 152
           DA G  +   S  + + YPTM++LAE +  V+ H  +K             L+R+ L H 
Sbjct: 27  DALGNPQ---SLGSRFVYPTMEQLAEAVHAVVEHYDLKCIIGFGVGAGANVLARYELAHH 197

Query: 153 ELVEGLVLINIDPCAKGWIDWAASK------LSGFTTNIVDIILAHHF 194
           + ++ LVL+N      GW++W   K      L G  TN  +  L  H+
Sbjct: 198 DRLDSLVLVNPLATQAGWVEWGYQKMNSWYLLGGQVTNFTEEYLLWHW 341
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|19526794|ref|NP_598416.1| CD 81 antigen [Mus
musculus]
         (236 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

31078                                                                  98   3e-21
25023                                                                  80   8e-16
11991                                                                  79   2e-15
16993                                                                  65   3e-11
21300                                                                  56   1e-08
34300                                                                  29   1.3  
>31078
          Length = 592

 Score = 97.8 bits (242), Expect = 3e-21,   Method: Compositional matrix adjust.
 Identities = 65/203 (32%), Positives = 98/203 (48%), Gaps = 2/203 (0%)
 Frame = +3

Query: 33  LWLRHDPQTTSLLYLELGNKPAPNTFYVGIYILIAVGAVMMFVGFLGCYGAIQESQCLLG 92
           +WLR DP     +     +  A N FY   Y+L+ +G ++M +GFLGC GAI+ESQC+L 
Sbjct: 6   IWLRVDPNVAKYV----NHAEAINIFYTMAYVLMVIGIIIMVIGFLGCCGAIRESQCMLA 173

Query: 93  TFFTCLVILFACEVAAGIWGFVNKDQIAKDVKQFYDQALQQAVMDDDANNAKAVVKTFHE 152
            FF  L I+FA  +  GIW    KD +   V    + A+      ++   ++  + T  E
Sbjct: 174 VFFVLLFIIFATLLGFGIWAVEEKDTLKVKVTSIMEVAVNTY---ENDKGSQQFMDTIQE 344

Query: 153 TLNCCGS--NALTTLTTTILRNSLCPSGGNILTPLLQQDCHQKIDELFSGKLYLIGXXXX 210
           +  CCGS  +A     T ++  S  P   +       + C +K  E  +  L ++     
Sbjct: 345 SFKCCGSSNSAQDYEKTMVVPESCIPEYRD-------EACDKKFFEWIAEHLVIVAGVAI 503

Query: 211 XXXXXMIFEMILSMVLCCGIRNS 233
                +I  MI SMVLCC IRN+
Sbjct: 504 AISIVLILGMIFSMVLCCAIRNT 572
>25023
          Length = 893

 Score = 80.1 bits (196), Expect = 8e-16,   Method: Compositional matrix adjust.
 Identities = 56/158 (35%), Positives = 81/158 (51%), Gaps = 3/158 (1%)
 Frame = -3

Query: 9   CIKYLLFVFNFVFWLAGGVILGVALWLRHDPQTTSLLYLELGNKPAPNTFYVGIYILIAV 68
           C+K L+ VFNF+FW+ G VIL + +W + D       YLEL +   P   YV    LI V
Sbjct: 756 CMKTLMMVFNFIFWVTGIVILAIGIWTKVDLYK----YLELSSIYQPEAPYV----LIGV 601

Query: 69  GAVMMFVGFLGCYGAIQESQCLLGTFFTCLVILFACEVAAGIWGFVNKDQIAKDVKQFYD 128
           GAV++ VG LGC   I+    LL  +   L ++F  E++AGI   V K ++ K  K    
Sbjct: 600 GAVIVLVGSLGCCCTIKGHAFLLYMYCGVLFLVFIMELSAGITLLVYKGKLEKGFK---- 433

Query: 129 QALQQAVMDDDANNAKAVVKTFHE---TLNCCGSNALT 163
           + L  A+   D    + +   F E    L+CCG N+ +
Sbjct: 432 EGLGSAIDRYDQKGEEEITAAFDELQQKLSCCGINSYS 319
>11991
          Length = 881

 Score = 78.6 bits (192), Expect = 2e-15,   Method: Compositional matrix adjust.
 Identities = 62/236 (26%), Positives = 105/236 (44%), Gaps = 9/236 (3%)
 Frame = -2

Query: 8   KCIKYLLFVFNFVFWLAGGVILGVALWLRHDPQTTSLLYLE----LGNKPAPNTFYVGIY 63
           K I+ L    NF+     G+++G+A+         + LY+E    L   P  +   V   
Sbjct: 877 KIIRGLFLFCNFL-----GIVMGIAM-----VAIGAYLYVEKNDFLNLMPKYDDINVTA- 731

Query: 64  ILIAVGAVMMFVGFLGCYGAIQESQCLLGTFFTCLVILFACEVAAGIWGFVNKDQIAKDV 123
           ++IA G V++ +  +G  GA  ESQC+L  FFT + I+FA E+A GI GF+ +D I  ++
Sbjct: 730 VMIAAGIVVLVIACIGFCGAWMESQCMLIMFFTAIFIIFAMEIAVGIIGFIYRDDIDSEL 551

Query: 124 KQFYDQALQQAVMDDDANNAKAVVKTFHETLNCCGSNALTTLTTTILR---NSLCPSGGN 180
                + L++           +      +  +CCG +      T ++    +S C     
Sbjct: 550 NTQLKEGLKEP-------KRHSTWDVIQKEYDCCGVDTYQDWFTVLVNRVPDSCCSHTNC 392

Query: 181 ILTPLLQQD--CHQKIDELFSGKLYLIGXXXXXXXXXMIFEMILSMVLCCGIRNSS 234
              P L  D  C+ K+ E      Y++G          I  ++++MVL C IR + 
Sbjct: 391 GTNPQLASDXGCYSKVKEEIEDHFYVLGAAGIALGVLQILLLVMTMVLICAIRRTR 224
>16993
          Length = 2290

 Score = 64.7 bits (156), Expect = 3e-11,   Method: Compositional matrix adjust.
 Identities = 51/166 (30%), Positives = 80/166 (48%), Gaps = 1/166 (0%)
 Frame = -2

Query: 3    VEGCTKCIKYLLFVFNFVFWLAGGVILGVALWLRHDPQTTSLLYLELGNK-PAPNTFYVG 61
            VEG  KC+KYLLF FN +F +A   ++    +++      S  Y   GN+   P      
Sbjct: 2205 VEGGMKCVKYLLFGFNLIFVIAAIGLIAAGAYVQ---IKLSDYYDFFGNEYTGPGI---- 2047

Query: 62   IYILIAVGAVMMFVGFLGCYGAIQESQCLLGTFFTCLVILFACEVAAGIWGFVNKDQIAK 121
              +LI VGA +  + F GC GA++E+ CL  +F   L ++F   +A GI  +V +D++  
Sbjct: 2046 --LLICVGAFIFIIAFFGCMGALKENYCLTMSFAVLLAVIFILMIAGGIAAYVLRDKVES 1873

Query: 122  DVKQFYDQALQQAVMDDDANNAKAVVKTFHETLNCCGSNALTTLTT 167
            +V      A ++   DDD+   K         +NC  S+     TT
Sbjct: 1872 EVLTILKDAEKR--YDDDSGVKKL-------GINCRQSSPAVVHTT 1762
>21300
          Length = 843

 Score = 55.8 bits (133), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 45/189 (23%), Positives = 76/189 (40%), Gaps = 20/189 (10%)
 Frame = -2

Query: 64  ILIAVGAVMMFVGFLGCYGAIQESQCLLGTFFTCLVILFACEVAAGIWGFVNKDQIAKDV 123
           I++ V   M  +G LGC    +ES+ LL  +F  ++++F  EV AG+ G+  ++++ K V
Sbjct: 752 IVLGVAVFMFLIGLLGCIAVCKESKILLSFYFCLILVVFLGEVVAGVLGYAYRNEVEKAV 573

Query: 124 KQFYDQAL---QQAVMDDDANNAKAVVKTFHETLNCCG---------SNALTTLTTTILR 171
                +A+    + VM D  N  +         L+CCG         S A +   T  + 
Sbjct: 572 SDGLTKAVDNWNETVMQDQMNYVQT-------QLHCCGVQNSSDWATSAAWSVNHTNTVP 414

Query: 172 NSLCPSGGNIL--------TPLLQQDCHQKIDELFSGKLYLIGXXXXXXXXXMIFEMILS 223
            S C    N+           +  Q C   ++  F+  L  I           I  +I +
Sbjct: 413 TSCCIDQANLTLCDTTIGSKQIYNQGCLPALEHKFTTNLVYIASVTLAFALIQILGLIST 234

Query: 224 MVLCCGIRN 232
            +L C  R 
Sbjct: 233 CILICRTRE 207
>34300
          Length = 336

 Score = 29.3 bits (64), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 23/84 (27%), Positives = 40/84 (47%)
 Frame = -3

Query: 56  NTFYVGIYILIAVGAVMMFVGFLGCYGAIQESQCLLGTFFTCLVILFACEVAAGIWGFVN 115
           + +  G+Y+LIA GAV + +     +G   E    LGT F  +++L    +A  I GFV 
Sbjct: 280 DLYKAGVYLLIAGGAVTVLIPLWLLWGRHGEPLS-LGTDFAVMLVLTIFFIAVCIIGFVF 104

Query: 116 KDQIAKDVKQFYDQALQQAVMDDD 139
           +  I   +++  +  L     +D 
Sbjct: 103 RGNITGHLQREAETTLIYKYGEDS 32
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|71061458|ref|NP_690029.2| dynamin 1-like isoform a
[Mus musculus]
         (712 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

29522                                                                 100   3e-21
38072                                                                  35   0.15 
>29522
          Length = 698

 Score = 99.8 bits (247), Expect = 3e-21,   Method: Compositional matrix adjust.
 Identities = 55/154 (35%), Positives = 88/154 (57%)
 Frame = -3

Query: 361 IEGTAKYIETSELCGGARICYIFHETFGRTLESVDPLGGLNTIDILTAIRNATGPRPALF 420
           IEG    + T +L GGA+I  IFHE F   L  ++        +I   IRN  G R  LF
Sbjct: 696 IEGFGAQVSTEDLSGGAKINRIFHERFPFELVKMEFDERELRKEIGITIRNIHGIRTGLF 517

Query: 421 VPEVSFELLVKRQIKRLEEPSLRCVELVHEEMQRIIQHCSNYSTQELLRFPKLHDAIVEV 480
            P+++FE +V +QI+RL+EPSL CV+LV  E+ ++++       +++ R+P+L +    +
Sbjct: 516 TPDMAFESIVVKQIERLKEPSLHCVDLVITELSQVVRKAG----EKMSRYPRLREETERI 349

Query: 481 VTCLLRKRLPVTNEMVHNLVAIELAYINTKHPDF 514
           V   +R++     E +  L+  +LAY+NT H DF
Sbjct: 348 VNSRIREQEQRAKEQILTLIDFQLAYMNTNHEDF 247
>38072
          Length = 513

 Score = 34.7 bits (78), Expect = 0.15,   Method: Compositional matrix adjust.
 Identities = 15/40 (37%), Positives = 23/40 (57%)
 Frame = -3

Query: 617 QRDCEVIERLIKSYFLIVRKNIQDSVPKAVMHFLVNHVKD 656
           +R  E I  L+ SY  IV K  +D +PK +MH +V   ++
Sbjct: 397 ERQVETIRNLVDSYMKIVNKTQRDLIPKTIMHIIVKKCEE 278
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6679066|ref|NP_032724.1| 4-nitrophenylphosphatase
domain and non-neuronal SNAP25-like protein homolog 1 [Mus musculus]
         (284 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

08476                                                                  98   4e-21
06725                                                                  45   4e-05
39349                                                                  28   3.1  
>08476
          Length = 2241

 Score = 98.2 bits (243), Expect = 4e-21,   Method: Compositional matrix adjust.
 Identities = 45/72 (62%), Positives = 55/72 (76%), Gaps = 1/72 (1%)
 Frame = -3

Query: 214  NQEAVGGFFSQIGELYV-VHHLWAYKDLQSREETRNAAWRKRGWDENVYYTVPLVRHMES 272
            N E V GFFSQ G   + VHH+WAY DL++R+ TR AAW++ GWDE V YTVPL+RHM+S
Sbjct: 2236 NNEPVAGFFSQDGGTCIWVHHIWAYTDLETRKITREAAWQRPGWDECVAYTVPLIRHMQS 2057

Query: 273  RIMIPLKISPLQ 284
            RI+IP   SPLQ
Sbjct: 2056 RILIPTPFSPLQ 2021
>06725
          Length = 739

 Score = 44.7 bits (104), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 28/118 (23%), Positives = 54/118 (45%), Gaps = 1/118 (0%)
 Frame = -1

Query: 160 LSRRNQLLLEFSFWNEPQPRAGPNIYELRTYKLKPGTMIEWGNNWARAIKYRQENQEAVG 219
           L+R+ Q     S  N P+   G ++YELR Y +KP     +    A     R    + +G
Sbjct: 712 LARQQQTRNYSSSNNGPESSQG-SVYELRIYSIKPDMFGTFRQLMADKFHLRFPYSKPIG 536

Query: 220 GFFSQIGELYVVHHLWAYKDLQSREETRNAAWRKRGWDENVYYT-VPLVRHMESRIMI 276
            + + +G ++   H+W Y+ +  R   R A    + W +  +   +P +  M++ +M+
Sbjct: 535 YWIADLGGIFQAVHIWPYESVSERGRIRQAMAVDQEWQQEFFLKFMPCLIRMDNSMMV 362

 Score = 30.0 bits (66), Expect = 1.0,   Method: Compositional matrix adjust.
 Identities = 16/64 (25%), Positives = 32/64 (50%)
 Frame = -1

Query: 65  KKETSNLYKIQFHNVKPECLDAYNSLTEAVLPKLHLDEDYPCSLVGNWNTWYGEQDQAVH 124
           +    ++Y+++ +++KP   D + +  + +  K HL   Y    +G W    G   QAVH
Sbjct: 661 ESSQGSVYELRIYSIKP---DMFGTFRQLMADKFHLRFPY-SKPIGYWIADLGGIFQAVH 494

Query: 125 LWRF 128
           +W +
Sbjct: 493 IWPY 482
>39349
          Length = 592

 Score = 28.5 bits (62), Expect = 3.1,   Method: Compositional matrix adjust.
 Identities = 12/16 (75%), Positives = 13/16 (81%)
 Frame = -3

Query: 269 HMESRIMIPLKISPLQ 284
           HMESRI+IP   SPLQ
Sbjct: 590 HMESRILIPTPFSPLQ 543
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|189458800|ref|NP_032409.3| centrosomal protein 2
isoform 1 [Mus musculus]
         (2414 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

35266                                                                 100   5e-21
26041                                                                  48   5e-05
27823                                                                  35   0.30 
>35266
          Length = 601

 Score =  100 bits (250), Expect = 5e-21,   Method: Compositional matrix adjust.
 Identities = 47/92 (51%), Positives = 65/92 (70%)
 Frame = +1

Query: 123 MEKADVVNKALQEDVEKLTVDWSRARDELVRKESQWRMEQEFFKGYLRGEHGRLLNLWRE 182
           ++ A+ VN+ L  D+ KLT DW RAR+EL  KE++WR E++ F  Y   EHGRLL LWR 
Sbjct: 7   LDHANEVNQQLTSDIHKLTQDWQRAREELEAKEAEWRDEEKSFNEYFSAEHGRLLTLWRA 186

Query: 183 VVTFRRHFLKMKSATDRDLTELKAEHARLSGS 214
           VV FRR F +MK+AT+RDL+ ++A+  + S S
Sbjct: 187 VVAFRRQFSEMKTATERDLSHVRADVTKASRS 282
>26041
          Length = 418

 Score = 48.1 bits (113), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 26/52 (50%), Positives = 38/52 (73%)
 Frame = -3

Query: 22  QVLALQQQMAENQAASWRKLKNSQEAQKRQATLVRKLQAKVLQYRSWCQDLE 73
           Q L L++++ E  +   RKL++ Q+ Q+RQA LV+KLQAK+LQY+  C DLE
Sbjct: 329 QNLELRRKLEEEHSNYKRKLQSYQDGQQRQAQLVQKLQAKLLQYKQKCLDLE 174
>27823
          Length = 537

 Score = 35.4 bits (80), Expect = 0.30,   Method: Compositional matrix adjust.
 Identities = 21/45 (46%), Positives = 30/45 (66%)
 Frame = -3

Query: 22  QVLALQQQMAENQAASWRKLKNSQEAQKRQATLVRKLQAKVLQYR 66
           Q L L+ ++ E  +   RKL + QE Q RQA LV+KLQ+K+ QY+
Sbjct: 145 QNLELRHRLEEEHSLYKRKLLSYQEGQHRQAQLVQKLQSKLHQYK 11
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31543701|ref|NP_062632.2| soc-2 (suppressor of clear)
homolog [Mus musculus]
         (582 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

34576                                                                  99   6e-21
09309                                                                  79   4e-15
19531                                                                  76   3e-14
20480                                                                  67   2e-11
05532                                                                  55   6e-08
15446                                                                  41   0.002
30747                                                                  37   0.018
20775                                                                  36   0.033
17298                                                                  35   0.095
14078                                                                  33   0.35 
>34576
          Length = 1496

 Score = 98.6 bits (244), Expect = 6e-21,   Method: Compositional matrix adjust.
 Identities = 100/377 (26%), Positives = 160/377 (42%)
 Frame = +2

Query: 114 ILPPSVKELTQLTELYLYSNKLQSLPAEVGCLVNLMTLALSENSLTSLPDSLDNLKKLRM 173
           +LP  + EL +L E+Y  SN+L  +P  +    NL  L+L +N L  LP    NL+K+  
Sbjct: 20  VLPEDIAELFELKEVYCGSNQLTLIPESICWCSNLEILSLHKNHLERLPVEFANLRKITR 199

Query: 174 LDLRHNKLREIPSVVYRLDSLTTLYLRFNRITTVEKDIKNLPKLSMLSIRENKIKQLPAE 233
           L L  N    +P  +  L  L  L L  N +  + +++  L KL+ LS+  N  K+ P  
Sbjct: 200 LILSDNNFTSVPVAIGSLTELEALLLDGNSLHEIPQELGTLKKLTHLSLGRNAFKEFPRP 379

Query: 234 IGELCNLITLDVAHNQLEHLPKEIGNCTQITNXXXXXXXXXXXXXTIGNLSSLNRLGLRY 293
              + +L  LD++ N++  +P +                       I  L SL  L ++ 
Sbjct: 380 ACSITSLEILDLSDNKITEIPSD-----------------------IAQLLSLRELYMKK 490

Query: 294 NRLSAIPRSLAKCSAXXXXXXXXXXISTLPEXXXXXXXXXXXXXXARNCFQLYPVGGPSQ 353
           N +S     L               +  LPE                 C Q   +   +Q
Sbjct: 491 NAVSVFCAELCALQKLQMADFSNNGLLDLPE-----------EVSVLGCLQELDLSN-NQ 634

Query: 354 FSTIYSLNMEHNRINKIPFGIFSRAKVLSKLNMKDNQLTSLPLDFGTWTSMVELNLATNQ 413
           F            ++K+   +FS+ + L        ++ SLP D   ++S+ EL L+ N 
Sbjct: 635 FFEFPKTACSIPHLHKL---VFSQQEGL--------KVPSLP-DEIEFSSVAELVLSHNT 778

Query: 414 LTKIPEDVSGLVSLEVLILSNNLLKKLPHGLGNLRKLRELDLEENKLESLPNEIAYLKDL 473
           L  +P  +S + +L VL   +N +  LP  L ++  L+ L L +N L +LP E   LK L
Sbjct: 779 LRTLPRTISAMKNLVVLKADHNEICVLPDALCDMTALQVLHLNDNLLPTLPLEFDQLKGL 958

Query: 474 QKLVLTNNQLSTLPRGI 490
           Q L L NN L + P  +
Sbjct: 959 QDLCLHNNPLRSPPMDV 1009

 Score = 88.2 bits (217), Expect = 8e-18,   Method: Compositional matrix adjust.
 Identities = 83/320 (25%), Positives = 127/320 (39%), Gaps = 2/320 (0%)
 Frame = +2

Query: 104 RLDLSKRSIHILPPSVKELTQLTELYLYSNKLQSLPAEVGCLVNLMTLALSENSLTSLPD 163
           RL LS  +   +P ++  LT+L  L L  N L  +P E+G L  L  L+L  N+    P 
Sbjct: 197 RLILSDNNFTSVPVAIGSLTELEALLLDGNSLHEIPQELGTLKKLTHLSLGRNAFKEFPR 376

Query: 164 SLDNLKKLRMLDLRHNKLREIPSVVYRLDSLTTLYLRFNRITTVEKDIKNLPKLSMLSIR 223
              ++  L +LDL  NK+ EIPS + +L SL  LY++ N ++    ++  L KL M    
Sbjct: 377 PACSITSLEILDLSDNKITEIPSDIAQLLSLRELYMKKNAVSVFCAELCALQKLQMADFS 556

Query: 224 ENKIKQLPAEIGELCNLITLDVAHNQLEHLPKEIGNCTQITNXXXXXXXXXXXXXTIGNL 283
            N +  LP E+  L  L  LD+++NQ    PK   +   +                   +
Sbjct: 557 NNGLLDLPEEVSVLGCLQELDLSNNQFFEFPKTACSIPHLHKLVFSQQEGLKVPSLPDEI 736

Query: 284 --SSLNRLGLRYNRLSAIPRSLAKCSAXXXXXXXXXXISTLPEXXXXXXXXXXXXXXARN 341
             SS+  L L +N L  +PR++                                      
Sbjct: 737 EFSSVAELVLSHNTLRTLPRTI-------------------------------------- 802

Query: 342 CFQLYPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRAKVLSKLNMKDNQLTSLPLDFGTW 401
                     S    +  L  +HN I  +P  +      L  L++ DN L +LPL+F   
Sbjct: 803 ----------SAMKNLVVLKADHNEICVLPDAL-CDMTALQVLHLNDNLLPTLPLEFDQL 949

Query: 402 TSMVELNLATNQLTKIPEDV 421
             + +L L  N L   P DV
Sbjct: 950 KGLQDLCLHNNPLRSPPMDV 1009

 Score = 87.4 bits (215), Expect = 1e-17,   Method: Compositional matrix adjust.
 Identities = 95/381 (24%), Positives = 143/381 (37%), Gaps = 3/381 (0%)
 Frame = +2

Query: 97  CREENSMRLDLSKRSIHILPPSVKELTQLTELYLYSNKLQSLPAEVGCLVNLMTLALSEN 156
           C   N   L L K  +  LP     L ++T L L  N   S+P  +G L  L  L L  N
Sbjct: 107 CWCSNLEILSLHKNHLERLPVEFANLRKITRLILSDNNFTSVPVAIGSLTELEALLLDGN 286

Query: 157 SLTSLPDSLDNLKKLRMLDLRHNKLREIPSVVYRLDSLTTLYLRFNRITTVEKDIKNLPK 216
           SL  +P  L  LKKL  L L  N  +E P     + SL  L L  N+IT +  DI  L  
Sbjct: 287 SLHEIPQELGTLKKLTHLSLGRNAFKEFPRPACSITSLEILDLSDNKITEIPSDIAQLLS 466

Query: 217 LSMLSIRENKIKQLPAEIGELCNLITLDVAHNQLEHLPKEIGNCTQITNXXXXXXXXXXX 276
           L  L +++N +    AE+  L  L   D ++N L  LP+E                    
Sbjct: 467 LRELYMKKNAVSVFCAELCALQKLQMADFSNNGLLDLPEE-------------------- 586

Query: 277 XXTIGNLSSLNRLGLRYNRLSAIPR---SLAKCSAXXXXXXXXXXISTLPEXXXXXXXXX 333
              +  L  L  L L  N+    P+   S+               + +LP+         
Sbjct: 587 ---VSVLGCLQELDLSNNQFFEFPKTACSIPHLHKLVFSQQEGLKVPSLPDEI------- 736

Query: 334 XXXXXARNCFQLYPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRAKVLSKLNMKDNQLTS 393
                              +FS++  L + HN +  +P  I                   
Sbjct: 737 -------------------EFSSVAELVLSHNTLRTLPRTI------------------- 802

Query: 394 LPLDFGTWTSMVELNLATNQLTKIPEDVSGLVSLEVLILSNNLLKKLPHGLGNLRKLREL 453
                    ++V L    N++  +P+ +  + +L+VL L++NLL  LP     L+ L++L
Sbjct: 803 -----SAMKNLVVLKADHNEICVLPDALCDMTALQVLHLNDNLLPTLPLEFDQLKGLQDL 967

Query: 454 DLEENKLESLPNEIAYLKDLQ 474
            L  N L S P ++     LQ
Sbjct: 968 CLHNNPLRSPPMDVCVSGVLQ 1030

 Score = 70.5 bits (171), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 81/315 (25%), Positives = 119/315 (37%), Gaps = 26/315 (8%)
 Frame = +2

Query: 202 NRITTVEKDIKNLPKLSMLSIRENKIKQLPAEIGELCNLITLDVAHNQLEHLPKEIGNCT 261
           N +T + +DI  L +L  +    N++  +P  I    NL  L +  N LE LP E  N  
Sbjct: 8   NCLTVLPEDIAELFELKEVYCGSNQLTLIPESICWCSNLEILSLHKNHLERLPVEFANLR 187

Query: 262 QITNXXXXXXXXXXXXXTIGNLSSLNRLGLRYNRLSAIPRSLAKCSAXXXXXXXXXXIST 321
           +IT               IG+L+ L  L L  N L  IP+ L                  
Sbjct: 188 KITRLILSDNNFTSVPVAIGSLTELEALLLDGNSLHEIPQELG----------------- 316

Query: 322 LPEXXXXXXXXXXXXXXARNCFQLYPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRAKVL 381
                             RN F+ +P    S    I SL +                   
Sbjct: 317 -------TLKKLTHLSLGRNAFKEFPRPACS----ITSLEI------------------- 406

Query: 382 SKLNMKDNQLTSLPLDFGTWTSMVELNLATNQLTKIPEDVSGLVSLEVLILSNNLLKKLP 441
             L++ DN++T +P D     S+ EL +  N ++    ++  L  L++   SNN L  LP
Sbjct: 407 --LDLSDNKITEIPSDIAQLLSLRELYMKKNAVSVFCAELCALQKLQMADFSNNGLLDLP 580

Query: 442 HGLGNLRKLRELDLEEN--------------------------KLESLPNEIAYLKDLQK 475
             +  L  L+ELDL  N                          K+ SLP+EI +   + +
Sbjct: 581 EEVSVLGCLQELDLSNNQFFEFPKTACSIPHLHKLVFSQQEGLKVPSLPDEIEF-SSVAE 757

Query: 476 LVLTNNQLSTLPRGI 490
           LVL++N L TLPR I
Sbjct: 758 LVLSHNTLRTLPRTI 802

 Score = 67.0 bits (162), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 39/102 (38%), Positives = 57/102 (55%)
 Frame = +2

Query: 387 KDNQLTSLPLDFGTWTSMVELNLATNQLTKIPEDVSGLVSLEVLILSNNLLKKLPHGLGN 446
           ++N LT LP D      + E+   +NQLT IPE +    +LE+L L  N L++LP    N
Sbjct: 2   ENNCLTVLPEDIAELFELKEVYCGSNQLTLIPESICWCSNLEILSLHKNHLERLPVEFAN 181

Query: 447 LRKLRELDLEENKLESLPNEIAYLKDLQKLVLTNNQLSTLPR 488
           LRK+  L L +N   S+P  I  L +L+ L+L  N L  +P+
Sbjct: 182 LRKITRLILSDNNFTSVPVAIGSLTELEALLLDGNSLHEIPQ 307
>09309
          Length = 1508

 Score = 79.3 bits (194), Expect = 4e-15,   Method: Compositional matrix adjust.
 Identities = 55/167 (32%), Positives = 89/167 (53%), Gaps = 2/167 (1%)
 Frame = +3

Query: 84  KSSNAEVIKELNKCREENSMRLDLSKRSIHILPPSVKELTQ-LTELYLYSNKLQSLPAEV 142
           K++NA       K +E     +++SK     LP ++  L   LTEL +  NKL  L  ++
Sbjct: 384 KNANAVPADMWEKAQEAAVTSVNISKNQFTQLPSNLFLLVNSLTELNMGFNKLTGLSPDI 563

Query: 143 GCLVNLMTLALSENSLTSLPDSLDNLKKLRMLDLRHNKLREIPSVVYRLDSLTTLYLRFN 202
           G  + L  L L  N L+SLP  L +++ LR + L  N+  EIP  +Y L  L  L+L  N
Sbjct: 564 GLFLKLTCLDLRNNGLSSLPAELCSMQALREVILSCNRFTEIPQALYELKKLEILFLNDN 743

Query: 203 RITTVE-KDIKNLPKLSMLSIRENKIKQLPAEIGELCNLITLDVAHN 248
           +++T+E   ++ L  L+ L ++ N I Q+P E+G   +L +L +  N
Sbjct: 744 QVSTIEPSGLQRLGVLATLDLQNNNISQVPPELGNCTSLRSLQLGGN 884

 Score = 79.0 bits (193), Expect = 6e-15,   Method: Compositional matrix adjust.
 Identities = 57/193 (29%), Positives = 100/193 (51%), Gaps = 6/193 (3%)
 Frame = +3

Query: 77  PAPGTRKKSSNAEVIKELNKCREENSMR-LDLSKRSIHILPPSVKELTQ---LTELYLYS 132
           PAP T K+S       +  +  E    + +D S ++ + +P  + E  Q   +T + +  
Sbjct: 282 PAPVTSKESVLPTGSGDTQQAHEMQQFKTMDFSGKNANAVPADMWEKAQEAAVTSVNISK 461

Query: 133 NKLQSLPAEVGCLVNLMT-LALSENSLTSLPDSLDNLKKLRMLDLRHNKLREIPSVVYRL 191
           N+   LP+ +  LVN +T L +  N LT L   +    KL  LDLR+N L  +P+ +  +
Sbjct: 462 NQFTQLPSNLFLLVNSLTELNMGFNKLTGLSPDIGLFLKLTCLDLRNNGLSSLPAELCSM 641

Query: 192 DSLTTLYLRFNRITTVEKDIKNLPKLSMLSIRENKIKQL-PAEIGELCNLITLDVAHNQL 250
            +L  + L  NR T + + +  L KL +L + +N++  + P+ +  L  L TLD+ +N +
Sbjct: 642 QALREVILSCNRFTEIPQALYELKKLEILFLNDNQVSTIEPSGLQRLGVLATLDLQNNNI 821

Query: 251 EHLPKEIGNCTQI 263
             +P E+GNCT +
Sbjct: 822 SQVPPELGNCTSL 860

 Score = 58.5 bits (140), Expect = 8e-09,   Method: Compositional matrix adjust.
 Identities = 66/288 (22%), Positives = 119/288 (41%), Gaps = 8/288 (2%)
 Frame = +3

Query: 211 IKNLPKLSMLSIRENKIKQLPAEIGELCNLITLDVAHNQLEHLPKEIGNCTQITNXXXXX 270
           +++L  L+ L +R+NK+ +LP EI  L NL  LD+++N +  LP                
Sbjct: 6   LQHLSTLNFLDVRDNKLAKLPDEITLLENLERLDLSNNDISMLP---------------- 137

Query: 271 XXXXXXXXTIGNLSSLNRLGLRYNRLSAIPRSLAKCSAXXXXXXXXXXISTLPEXXXXXX 330
                   ++G ++SL  + L  N + +I R +               I   PE      
Sbjct: 138 -------YSLGTINSLKSVILDGNPMKSIRRDIIMRGTMELKKYLRSRIEE-PESRPAPV 293

Query: 331 XXXXXXXXARNCFQLYPVG-GPSQ----FSTIYSLNMEHNRINKIPFGIFSRAK--VLSK 383
                         + P G G +Q         +++      N +P  ++ +A+   ++ 
Sbjct: 294 TSKE---------SVLPTGSGDTQQAHEMQQFKTMDFSGKNANAVPADMWEKAQEAAVTS 446

Query: 384 LNMKDNQLTSLPLD-FGTWTSMVELNLATNQLTKIPEDVSGLVSLEVLILSNNLLKKLPH 442
           +N+  NQ T LP + F    S+ ELN+  N+LT +  D+                     
Sbjct: 447 VNISKNQFTQLPSNLFLLVNSLTELNMGFNKLTGLSPDI--------------------- 563

Query: 443 GLGNLRKLRELDLEENKLESLPNEIAYLKDLQKLVLTNNQLSTLPRGI 490
             G   KL  LDL  N L SLP E+  ++ L++++L+ N+ + +P+ +
Sbjct: 564 --GLFLKLTCLDLRNNGLSSLPAELCSMQALREVILSCNRFTEIPQAL 701

 Score = 58.2 bits (139), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 42/154 (27%), Positives = 76/154 (49%), Gaps = 24/154 (15%)
 Frame = +3

Query: 352 SQFSTIYSLNMEHNRINKIPFGIFSRAKVLSKLNM-----------------------KD 388
           +Q + + S+N+  N+  ++P  +F     L++LNM                       ++
Sbjct: 423 AQEAAVTSVNISKNQFTQLPSNLFLLVNSLTELNMGFNKLTGLSPDIGLFLKLTCLDLRN 602

Query: 389 NQLTSLPLDFGTWTSMVELNLATNQLTKIPEDVSGLVSLEVLILSNNLLKKL-PHGLGNL 447
           N L+SLP +  +  ++ E+ L+ N+ T+IP+ +  L  LE+L L++N +  + P GL  L
Sbjct: 603 NGLSSLPAELCSMQALREVILSCNRFTEIPQALYELKKLEILFLNDNQVSTIEPSGLQRL 782

Query: 448 RKLRELDLEENKLESLPNEIAYLKDLQKLVLTNN 481
             L  LDL+ N +  +P E+     L+ L L  N
Sbjct: 783 GVLATLDLQNNNISQVPPELGNCTSLRSLQLGGN 884

 Score = 47.0 bits (110), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 35/140 (25%), Positives = 71/140 (50%), Gaps = 5/140 (3%)
 Frame = +3

Query: 174 LDLRHNKLREIPSVVYRL-DSLTTLYLRFNRITTVEKDIKNLPKLSMLSIRENKIKQLPA 232
           +++  N+  ++PS ++ L +SLT L + FN++T +  DI    KL+ L +R N +  LPA
Sbjct: 447 VNISKNQFTQLPSNLFLLVNSLTELNMGFNKLTGLSPDIGLFLKLTCLDLRNNGLSSLPA 626

Query: 233 EIGELCNLITLDVAHNQLEHLPKEIGNCTQIT----NXXXXXXXXXXXXXTIGNLSSLNR 288
           E+  +  L  + ++ N+   +P+ +    ++     N              +G L++L+ 
Sbjct: 627 ELCSMQALREVILSCNRFTEIPQALYELKKLEILFLNDNQVSTIEPSGLQRLGVLATLD- 803

Query: 289 LGLRYNRLSAIPRSLAKCSA 308
             L+ N +S +P  L  C++
Sbjct: 804 --LQNNNISQVPPELGNCTS 857

 Score = 38.5 bits (88), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 63/315 (20%), Positives = 117/315 (37%), Gaps = 47/315 (14%)
 Frame = +3

Query: 145 LVNLMTLALSENSLTSLPDSLDNLKKLRMLDLRHNKLREIPSVVYRLDSLTTLYLRFNRI 204
           L  L  L + +N L  LPD +  L+ L  LDL +N +  +P  +  ++SL ++ L  N +
Sbjct: 15  LSTLNFLDVRDNKLAKLPDEITLLENLERLDLSNNDISMLPYSLGTINSLKSVILDGNPM 194

Query: 205 TTVEKDI------------------------------KNLPKLSMLSIRENKIKQ----- 229
            ++ +DI                                LP  S  + + ++++Q     
Sbjct: 195 KSIRRDIIMRGTMELKKYLRSRIEEPESRPAPVTSKESVLPTGSGDTQQAHEMQQFKTMD 374

Query: 230 --------LPAEIGELCN---LITLDVAHNQLEHLPKEIG-NCTQITNXXXXXXXXXXXX 277
                   +PA++ E      + +++++ NQ   LP  +      +T             
Sbjct: 375 FSGKNANAVPADMWEKAQEAAVTSVNISKNQFTQLPSNLFLLVNSLTELNMGFNKLTGLS 554

Query: 278 XTIGNLSSLNRLGLRYNRLSAIPRSLAKCSAXXXXXXXXXXISTLPEXXXXXXXXXXXXX 337
             IG    L  L LR N LS++P  L    A           + +P+             
Sbjct: 555 PDIGLFLKLTCLDLRNNGLSSLPAELCSMQALREVILSCNRFTEIPQA------------ 698

Query: 338 XARNCFQLYPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRAKVLSKLNMKDNQLTSLPLD 397
                  LY      +   +  L +  N+++ I      R  VL+ L++++N ++ +P +
Sbjct: 699 -------LY------ELKKLEILFLNDNQVSTIEPSGLQRLGVLATLDLQNNNISQVPPE 839

Query: 398 FGTWTSMVELNLATN 412
            G  TS+  L L  N
Sbjct: 840 LGNCTSLRSLQLGGN 884
>19531
          Length = 415

 Score = 76.3 bits (186), Expect = 3e-14,   Method: Compositional matrix adjust.
 Identities = 47/126 (37%), Positives = 74/126 (58%)
 Frame = -2

Query: 121 ELTQLTELYLYSNKLQSLPAEVGCLVNLMTLALSENSLTSLPDSLDNLKKLRMLDLRHNK 180
           E T LT+L L SN L SL   +  L  L  L + +N L SLP++L  L+ L+ L++ HN+
Sbjct: 378 EQTDLTKLILASNALTSLGEGLAQLPALTVLDVHDNHLQSLPNALGELENLQKLNISHNQ 199

Query: 181 LREIPSVVYRLDSLTTLYLRFNRITTVEKDIKNLPKLSMLSIRENKIKQLPAEIGELCNL 240
           L E+PS + RL +L +++   N++T +  D+ +  KL  L +  N + +LP  IG L  +
Sbjct: 198 LVELPSCIGRLSNLVSVHAEHNKLTLICPDLVDCRKLEELDVSNNDLAELPKYIGLLSRM 19

Query: 241 ITLDVA 246
             L+VA
Sbjct: 18  FRLNVA 1

 Score = 54.3 bits (129), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 32/116 (27%), Positives = 58/116 (50%)
 Frame = -2

Query: 189 YRLDSLTTLYLRFNRITTVEKDIKNLPKLSMLSIRENKIKQLPAEIGELCNLITLDVAHN 248
           +    LT L L  N +T++ + +  LP L++L + +N ++ LP  +GEL NL  L+++HN
Sbjct: 381 WEQTDLTKLILASNALTSLGEGLAQLPALTVLDVHDNHLQSLPNALGELENLQKLNISHN 202

Query: 249 QLEHLPKEIGNCTQITNXXXXXXXXXXXXXTIGNLSSLNRLGLRYNRLSAIPRSLA 304
           QL  LP  IG  + + +              + +   L  L +  N L+ +P+ + 
Sbjct: 201 QLVELPSCIGRLSNLVSVHAEHNKLTLICPDLVDCRKLEELDVSNNDLAELPKYIG 34

 Score = 47.8 bits (112), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 35/110 (31%), Positives = 60/110 (54%)
 Frame = -2

Query: 381 LSKLNMKDNQLTSLPLDFGTWTSMVELNLATNQLTKIPEDVSGLVSLEVLILSNNLLKKL 440
           L+KL +  N LTSL        ++  L++  N L  +P  +  L +L+ L +S+N L +L
Sbjct: 366 LTKLILASNALTSLGEGLAQLPALTVLDVHDNHLQSLPNALGELENLQKLNISHNQLVEL 187

Query: 441 PHGLGNLRKLRELDLEENKLESLPNEIAYLKDLQKLVLTNNQLSTLPRGI 490
           P  +G L  L  +  E NKL  +  ++   + L++L ++NN L+ LP+ I
Sbjct: 186 PSCIGRLSNLVSVHAEHNKLTLICPDLVDCRKLEELDVSNNDLAELPKYI 37

 Score = 47.4 bits (111), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 33/102 (32%), Positives = 54/102 (52%)
 Frame = -2

Query: 375 FSRAKVLSKLNMKDNQLTSLPLDFGTWTSMVELNLATNQLTKIPEDVSGLVSLEVLILSN 434
            ++   L+ L++ DN L SLP   G   ++ +LN++ NQL ++P  +  L +L  +   +
Sbjct: 315 LAQLPALTVLDVHDNHLQSLPNALGELENLQKLNISHNQLVELPSCIGRLSNLVSVHAEH 136

Query: 435 NLLKKLPHGLGNLRKLRELDLEENKLESLPNEIAYLKDLQKL 476
           N L  +   L + RKL ELD+  N L  LP  I  L  + +L
Sbjct: 135 NKLTLICPDLVDCRKLEELDVSNNDLAELPKYIGLLSRMFRL 10

 Score = 46.6 bits (109), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 39/145 (26%), Positives = 69/145 (47%)
 Frame = -2

Query: 147 NLMTLALSENSLTSLPDSLDNLKKLRMLDLRHNKLREIPSVVYRLDSLTTLYLRFNRITT 206
           +L  L L+ N+LTSL + L  L  L +LD+  N L+ +P+ +                  
Sbjct: 369 DLTKLILASNALTSLGEGLAQLPALTVLDVHDNHLQSLPNAL------------------ 244

Query: 207 VEKDIKNLPKLSMLSIRENKIKQLPAEIGELCNLITLDVAHNQLEHLPKEIGNCTQITNX 266
              +++NL KL+   I  N++ +LP+ IG L NL+++   HN+L  +  ++ +C ++   
Sbjct: 243 --GELENLQKLN---ISHNQLVELPSCIGRLSNLVSVHAEHNKLTLICPDLVDCRKLEEL 79

Query: 267 XXXXXXXXXXXXTIGNLSSLNRLGL 291
                        IG LS + RL +
Sbjct: 78  DVSNNDLAELPKYIGLLSRMFRLNV 4

 Score = 45.4 bits (106), Expect = 6e-05,   Method: Compositional matrix adjust.
 Identities = 33/106 (31%), Positives = 56/106 (52%)
 Frame = -2

Query: 350 GPSQFSTIYSLNMEHNRINKIPFGIFSRAKVLSKLNMKDNQLTSLPLDFGTWTSMVELNL 409
           G +Q   +  L++  N +  +P  +    + L KLN+  NQL  LP   G  +++V ++ 
Sbjct: 318 GLAQLPALTVLDVHDNHLQSLPNAL-GELENLQKLNISHNQLVELPSCIGRLSNLVSVHA 142

Query: 410 ATNQLTKIPEDVSGLVSLEVLILSNNLLKKLPHGLGNLRKLRELDL 455
             N+LT I  D+     LE L +SNN L +LP  +G L ++  L++
Sbjct: 141 EHNKLTLICPDLVDCRKLEELDVSNNDLAELPKYIGLLSRMFRLNV 4
>20480
          Length = 638

 Score = 66.6 bits (161), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 38/110 (34%), Positives = 62/110 (56%)
 Frame = -1

Query: 105 LDLSKRSIHILPPSVKELTQLTELYLYSNKLQSLPAEVGCLVNLMTLALSENSLTSLPDS 164
           LDLS   I  +   +  L  L +L L  NK++++P  +G +  L  L ++EN L  +PDS
Sbjct: 419 LDLSNNDIEAVSSELSGLQTLRQLILNGNKMEAIPGSIGFMKELRVLGVNENRLREVPDS 240

Query: 165 LDNLKKLRMLDLRHNKLREIPSVVYRLDSLTTLYLRFNRITTVEKDIKNL 214
           + NL+ L +L L  N L  +  VV +L+ L  L L  N +T + ++++NL
Sbjct: 239 IGNLENLEILGLERNCLEFLNPVVCKLEGLLRLGLSGNHMTNLPREVENL 90

 Score = 54.7 bits (130), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 39/126 (30%), Positives = 64/126 (50%)
 Frame = -1

Query: 134 KLQSLPAEVGCLVNLMTLALSENSLTSLPDSLDNLKKLRMLDLRHNKLREIPSVVYRLDS 193
           +LQ++   V  L  L  L LS N + ++   L  L+ LR L L  NK+  IP  +  +  
Sbjct: 470 QLQAVNRSVFRLPKLQILDLSNNDIEAVSSELSGLQTLRQLILNGNKMEAIPGSIGFMKE 291

Query: 194 LTTLYLRFNRITTVEKDIKNLPKLSMLSIRENKIKQLPAEIGELCNLITLDVAHNQLEHL 253
           L  L +  NR+  V   I NL  L +L +  N ++ L   + +L  L+ L ++ N + +L
Sbjct: 290 LRVLGVNENRLREVPDSIGNLENLEILGLERNCLEFLNPVVCKLEGLLRLGLSGNHMTNL 111

Query: 254 PKEIGN 259
           P+E+ N
Sbjct: 110 PREVEN 93

 Score = 50.1 bits (118), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 36/124 (29%), Positives = 55/124 (44%)
 Frame = -1

Query: 180 KLREIPSVVYRLDSLTTLYLRFNRITTVEKDIKNLPKLSMLSIRENKIKQLPAEIGELCN 239
           +L+ +   V+RL  L  L L  N I  V  ++  L  L  L +  NK++ +P  IG +  
Sbjct: 470 QLQAVNRSVFRLPKLQILDLSNNDIEAVSSELSGLQTLRQLILNGNKMEAIPGSIGFMKE 291

Query: 240 LITLDVAHNQLEHLPKEIGNCTQITNXXXXXXXXXXXXXTIGNLSSLNRLGLRYNRLSAI 299
           L  L V  N+L  +P  IGN   +                +  L  L RLGL  N ++ +
Sbjct: 290 LRVLGVNENRLREVPDSIGNLENLEILGLERNCLEFLNPVVCKLEGLLRLGLSGNHMTNL 111

Query: 300 PRSL 303
           PR +
Sbjct: 110 PREV 99

 Score = 48.9 bits (115), Expect = 6e-06,   Method: Compositional matrix adjust.
 Identities = 28/80 (35%), Positives = 50/80 (62%)
 Frame = -1

Query: 407 LNLATNQLTKIPEDVSGLVSLEVLILSNNLLKKLPHGLGNLRKLRELDLEENKLESLPNE 466
           L+L+ N +  +  ++SGL +L  LIL+ N ++ +P  +G +++LR L + EN+L  +P+ 
Sbjct: 419 LDLSNNDIEAVSSELSGLQTLRQLILNGNKMEAIPGSIGFMKELRVLGVNENRLREVPDS 240

Query: 467 IAYLKDLQKLVLTNNQLSTL 486
           I  L++L+ L L  N L  L
Sbjct: 239 IGNLENLEILGLERNCLEFL 180

 Score = 46.2 bits (108), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 28/78 (35%), Positives = 46/78 (58%)
 Frame = -1

Query: 413 QLTKIPEDVSGLVSLEVLILSNNLLKKLPHGLGNLRKLRELDLEENKLESLPNEIAYLKD 472
           QL  +   V  L  L++L LSNN ++ +   L  L+ LR+L L  NK+E++P  I ++K+
Sbjct: 470 QLQAVNRSVFRLPKLQILDLSNNDIEAVSSELSGLQTLRQLILNGNKMEAIPGSIGFMKE 291

Query: 473 LQKLVLTNNQLSTLPRGI 490
           L+ L +  N+L  +P  I
Sbjct: 290 LRVLGVNENRLREVPDSI 237

 Score = 39.7 bits (91), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 22/51 (43%), Positives = 34/51 (66%)
 Frame = -2

Query: 385 NMKDNQLTSLPLDFGTWTSMVELNLATNQLTKIPEDVSGLVSLEVLILSNN 435
           +M D QLT +P        +V L+L+ N++T+IP+ +S L +LEVL+LS N
Sbjct: 622 DMGDLQLTQMPDPVFDLEQLVCLSLSNNKITEIPDAISHLDNLEVLVLSGN 470

 Score = 36.6 bits (83), Expect = 0.026,   Method: Compositional matrix adjust.
 Identities = 19/45 (42%), Positives = 28/45 (62%)
 Frame = -2

Query: 158 LTSLPDSLDNLKKLRMLDLRHNKLREIPSVVYRLDSLTTLYLRFN 202
           LT +PD + +L++L  L L +NK+ EIP  +  LD+L  L L  N
Sbjct: 604 LTQMPDPVFDLEQLVCLSLSNNKITEIPDAISHLDNLEVLVLSGN 470

 Score = 33.5 bits (75), Expect = 0.22,   Method: Compositional matrix adjust.
 Identities = 16/45 (35%), Positives = 29/45 (64%)
 Frame = -2

Query: 437 LKKLPHGLGNLRKLRELDLEENKLESLPNEIAYLKDLQKLVLTNN 481
           L ++P  + +L +L  L L  NK+  +P+ I++L +L+ LVL+ N
Sbjct: 604 LTQMPDPVFDLEQLVCLSLSNNKITEIPDAISHLDNLEVLVLSGN 470

 Score = 30.4 bits (67), Expect = 1.8,   Method: Compositional matrix adjust.
 Identities = 18/47 (38%), Positives = 26/47 (55%)
 Frame = -2

Query: 413 QLTKIPEDVSGLVSLEVLILSNNLLKKLPHGLGNLRKLRELDLEENK 459
           QLT++P+ V  L  L  L LSNN + ++P  + +L  L  L L  N 
Sbjct: 607 QLTQMPDPVFDLEQLVCLSLSNNKITEIPDAISHLDNLEVLVLSGNS 467
>05532
          Length = 1607

 Score = 55.5 bits (132), Expect = 6e-08,   Method: Compositional matrix adjust.
 Identities = 31/85 (36%), Positives = 46/85 (54%)
 Frame = +3

Query: 181 LREIPSVVYRLDSLTTLYLRFNRITTVEKDIKNLPKLSMLSIRENKIKQLPAEIGELCNL 240
           +R I   ++R   LT LYL  NR+  +   +  L  L  L +  N++  LP+EIG+L  L
Sbjct: 144 VRNISPELFRFQHLTCLYLNDNRLDHISPHVSQLHHLVCLDLSSNQLSSLPSEIGDLTEL 323

Query: 241 ITLDVAHNQLEHLPKEIGNCTQITN 265
             L + +NQL  LP E+G   Q+ N
Sbjct: 324 RELLLYNNQLTSLPFELGRLFQLQN 398

 Score = 53.1 bits (126), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 37/110 (33%), Positives = 58/110 (52%)
 Frame = +3

Query: 377 RAKVLSKLNMKDNQLTSLPLDFGTWTSMVELNLATNQLTKIPEDVSGLVSLEVLILSNNL 436
           R + L+ L + DN+L  +         +V L+L++NQL+ +P ++  L  L  L+L NN 
Sbjct: 171 RFQHLTCLYLNDNRLDHISPHVSQLHHLVCLDLSSNQLSSLPSEIGDLTELRELLLYNNQ 350

Query: 437 LKKLPHGLGNLRKLRELDLEENKLESLPNEIAYLKDLQKLVLTNNQLSTL 486
           L  LP  LG L +L+ LD++ N L        Y+   Q +  TN+ LS L
Sbjct: 351 LTSLPFELGRLFQLQNLDIKGNPLSQ-----DYMHFYQGMNGTNDLLSFL 485

 Score = 50.8 bits (120), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 38/87 (43%), Positives = 47/87 (54%)
 Frame = +3

Query: 97  CREENSMRLDLSKRSIHILPPSVKELTQLTELYLYSNKLQSLPAEVGCLVNLMTLALSEN 156
           C   N  RLD      HI  P V +L  L  L L SN+L SLP+E+G L  L  L L  N
Sbjct: 189 CLYLNDNRLD------HI-SPHVSQLHHLVCLDLSSNQLSSLPSEIGDLTELRELLLYNN 347

Query: 157 SLTSLPDSLDNLKKLRMLDLRHNKLRE 183
            LTSLP  L  L +L+ LD++ N L +
Sbjct: 348 QLTSLPFELGRLFQLQNLDIKGNPLSQ 428

 Score = 48.1 bits (113), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 32/88 (36%), Positives = 48/88 (54%)
 Frame = +3

Query: 115 LPPSVKELTQLTELYLYSNKLQSLPAEVGCLVNLMTLALSENSLTSLPDSLDNLKKLRML 174
           + P +     LT LYL  N+L  +   V  L +L+ L LS N L+SLP  + +L +LR L
Sbjct: 153 ISPELFRFQHLTCLYLNDNRLDHISPHVSQLHHLVCLDLSSNQLSSLPSEIGDLTELREL 332

Query: 175 DLRHNKLREIPSVVYRLDSLTTLYLRFN 202
            L +N+L  +P  + RL  L  L ++ N
Sbjct: 333 LLYNNQLTSLPFELGRLFQLQNLDIKGN 416

 Score = 46.6 bits (109), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 31/78 (39%), Positives = 44/78 (56%), Gaps = 11/78 (14%)
 Frame = +3

Query: 421 VSGLV-----------SLEVLILSNNLLKKLPHGLGNLRKLRELDLEENKLESLPNEIAY 469
           +SGLV            L  L L++N L  +   +  L  L  LDL  N+L SLP+EI  
Sbjct: 132 ISGLVRNISPELFRFQHLTCLYLNDNRLDHISPHVSQLHHLVCLDLSSNQLSSLPSEIGD 311

Query: 470 LKDLQKLVLTNNQLSTLP 487
           L +L++L+L NNQL++LP
Sbjct: 312 LTELRELLLYNNQLTSLP 365

 Score = 41.6 bits (96), Expect = 9e-04,   Method: Compositional matrix adjust.
 Identities = 23/94 (24%), Positives = 45/94 (47%)
 Frame = +3

Query: 204 ITTVEKDIKNLPKLSMLSIRENKIKQLPAEIGELCNLITLDVAHNQLEHLPKEIGNCTQI 263
           +  +  ++     L+ L + +N++  +   + +L +L+ LD++ NQL  LP EIG+ T++
Sbjct: 144 VRNISPELFRFQHLTCLYLNDNRLDHISPHVSQLHHLVCLDLSSNQLSSLPSEIGDLTEL 323

Query: 264 TNXXXXXXXXXXXXXTIGNLSSLNRLGLRYNRLS 297
                           +G L  L  L ++ N LS
Sbjct: 324 RELLLYNNQLTSLPFELGRLFQLQNLDIKGNPLS 425

 Score = 39.7 bits (91), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 27/83 (32%), Positives = 43/83 (51%)
 Frame = +3

Query: 168 LKKLRMLDLRHNKLREIPSVVYRLDSLTTLYLRFNRITTVEKDIKNLPKLSMLSIRENKI 227
            + L  L L  N+L  I   V +L  L  L L  N+++++  +I +L +L  L +  N++
Sbjct: 174 FQHLTCLYLNDNRLDHISPHVSQLHHLVCLDLSSNQLSSLPSEIGDLTELRELLLYNNQL 353

Query: 228 KQLPAEIGELCNLITLDVAHNQL 250
             LP E+G L  L  LD+  N L
Sbjct: 354 TSLPFELGRLFQLQNLDIKGNPL 422

 Score = 37.4 bits (85), Expect = 0.018,   Method: Compositional matrix adjust.
 Identities = 28/98 (28%), Positives = 50/98 (51%)
 Frame = +3

Query: 132 SNKLQSLPAEVGCLVNLMTLALSENSLTSLPDSLDNLKKLRMLDLRHNKLREIPSVVYRL 191
           S  ++++  E+    +L  L L++N L  +   +  L  L  LDL  N+L  +PS +  L
Sbjct: 135 SGLVRNISPELFRFQHLTCLYLNDNRLDHISPHVSQLHHLVCLDLSSNQLSSLPSEIGDL 314

Query: 192 DSLTTLYLRFNRITTVEKDIKNLPKLSMLSIRENKIKQ 229
             L  L L  N++T++  ++  L +L  L I+ N + Q
Sbjct: 315 TELRELLLYNNQLTSLPFELGRLFQLQNLDIKGNPLSQ 428
>15446
          Length = 401

 Score = 40.8 bits (94), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 38/108 (35%), Positives = 57/108 (52%), Gaps = 2/108 (1%)
 Frame = -3

Query: 105 LDLSKRSIHILPPSVKELTQLTELYLYSNKLQSLPA-EVGCLVNLMTLALSENSLTSLPD 163
           +D S+R +  +P  ++  +  T L L SN + SL A +   L  L  L LS N +T +  
Sbjct: 321 IDCSERGLVEVPNDLQLRSWGTRLELQSNGITSLEAGDFKGLHMLEELYLSHNDITFING 142

Query: 164 SL-DNLKKLRMLDLRHNKLREIPSVVYRLDSLTTLYLRFNRITTVEKD 210
           S+  +L KL  L + HNKL E+P V  R  ++T L L  N I T+  +
Sbjct: 141 SIFQDLIKLHTLKITHNKLTEMP-VFPRHLNITELSLAHNMIHTISHE 1
>30747
          Length = 1168

 Score = 37.4 bits (85), Expect = 0.018,   Method: Compositional matrix adjust.
 Identities = 57/181 (31%), Positives = 91/181 (50%), Gaps = 9/181 (4%)
 Frame = +3

Query: 92  KELNKCREENSMRLDLSKRSIHILPPSVKELTQLTELYLYSNKLQSLPAEVGCLVNLMTL 151
           K LN  ++   +RLD S R   +    +     ++ L L +N + +L A +  L NL  L
Sbjct: 444 KGLNALKKLKCLRLD-SNRLTKLDTNELLSCVNISTLDLSNNHITNLSA-LSYLPNLEEL 617

Query: 152 ALSENSLTSLPDSLDNLKKLRMLDLRHNKLREIPSVVYRLDSLTTLYLRFNRITTVEKDI 211
            +S NS+  L D L   KKL  LDL  N+L +I S +  L +L TL +  NR+ +V   +
Sbjct: 618 FVSGNSIQKLTD-LHRCKKLSELDLSRNRLVDI-SGISGLPALQTLDMSDNRLKSVTS-L 788

Query: 212 KNLPKLSMLSIRENKIKQLPA--------EIGELC-NLITLDVAHNQLEHLPKEIGNCTQ 262
             L  L  L++  N+I +L          +I +LC N++T   A  Q+  L KE+G+  +
Sbjct: 789 GKLKSLETLNLNGNQISELLGWGSCFPKLQILKLCDNMVT---AWKQVCCL-KELGDLNE 956

Query: 263 I 263
           +
Sbjct: 957 V 959

 Score = 33.9 bits (76), Expect = 0.21,   Method: Compositional matrix adjust.
 Identities = 81/343 (23%), Positives = 139/343 (40%), Gaps = 9/343 (2%)
 Frame = +3

Query: 104 RLDLSKRSIHILPPS-VKELTQLTELYLYSNKLQSLPAEVGCLVNLMTLALSENSLTSLP 162
           R D   R + I+ P+ + EL Q  + Y                  +  + L    +T++P
Sbjct: 117 RPDAKPRDVKIVSPAEILELCQEEDFY-----------------KVYEVDLHGTEITAVP 245

Query: 163 DSLDNLKKLRMLDLRHNKLREIPSVVYRLDSLTTLYLRFNRITTVEKDIKNLPKLSMLSI 222
           D L+  +KLR+LD+  N + +I  + +  D L  L L  N+++ V+  +++L +L  L +
Sbjct: 246 D-LEKFRKLRVLDVSGNYITKIQHLEFTQD-LRDLKLYDNKVSQVQ-GLESLKELCSLQL 416

Query: 223 RENKIKQLPAEIGELCNLITLDVAHNQLEHL-PKEIGNCTQITNXXXXXXXXXXXXXTIG 281
           + N+I+ L   +  L  L  L +  N+L  L   E+ +C                     
Sbjct: 417 QYNQIESLGKGLNALKKLKCLRLDSNRLTKLDTNELLSCV-------------------- 536

Query: 282 NLSSLNRLGLRYNRLSAIPRSLAKCSAXXXXXXXXXXISTLPEXXXXXXXXXXXXXXARN 341
           N+S+L+        LSA+                    S LP                 N
Sbjct: 537 NISTLDLSNNHITNLSAL--------------------SYLP-----------------N 605

Query: 342 CFQLYPVGGPSQFST-------IYSLNMEHNRINKIPFGIFSRAKVLSKLNMKDNQLTSL 394
             +L+  G   Q  T       +  L++  NR+  I  GI S    L  L+M DN+L S+
Sbjct: 606 LEELFVSGNSIQKLTDLHRCKKLSELDLSRNRLVDIS-GI-SGLPALQTLDMSDNRLKSV 779

Query: 395 PLDFGTWTSMVELNLATNQLTKIPEDVSGLVSLEVLILSNNLL 437
               G   S+  LNL  NQ++++    S    L++L L +N++
Sbjct: 780 T-SLGKLKSLETLNLNGNQISELLGWGSCFPKLQILKLCDNMV 905

 Score = 31.2 bits (69), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 42/151 (27%), Positives = 72/151 (47%), Gaps = 23/151 (15%)
 Frame = +3

Query: 359 SLNMEHNRINKIPFGIFSRAKVLSKLNMKDNQLTSLPLDFGTWTSMVELNLATNQLTKIP 418
            L +  N+++++  G+ S  K L  L ++ NQ+ SL         +  L L +N+LTK+ 
Sbjct: 339 DLKLYDNKVSQVQ-GLES-LKELCSLQLQYNQIESLGKGLNALKKLKCLRLDSNRLTKLD 512

Query: 419 ED-----------------------VSGLVSLEVLILSNNLLKKLPHGLGNLRKLRELDL 455
            +                       +S L +LE L +S N ++KL   L   +KL ELDL
Sbjct: 513 TNELLSCVNISTLDLSNNHITNLSALSYLPNLEELFVSGNSIQKLTD-LHRCKKLSELDL 689

Query: 456 EENKLESLPNEIAYLKDLQKLVLTNNQLSTL 486
             N+L  +   I+ L  LQ L +++N+L ++
Sbjct: 690 SRNRLVDISG-ISGLPALQTLDMSDNRLKSV 779
>20775
          Length = 1020

 Score = 36.2 bits (82), Expect = 0.033,   Method: Compositional matrix adjust.
 Identities = 46/182 (25%), Positives = 76/182 (41%), Gaps = 34/182 (18%)
 Frame = -3

Query: 103 MRLDLSKRSIHILPPSVKELTQLTELYLYSNKLQSLPAEVGCLVNLMTLALSENSLTSLP 162
           + LDLS  ++  LP +      +  L L +N   +LP  +  + +   L +S ++L S  
Sbjct: 580 INLDLSGNNLSTLPDNFLNGEIIDSLILKNNNFTALPVALTKVEHXRRLDVSFSALVSFS 401

Query: 163 -DSLDNLKKLRMLDLRHNKLREIPSV----------------------------VYRLDS 193
            D L+N+  L M+D+  NKL    +V                              R+D 
Sbjct: 400 FDILENVSGLEMVDMSSNKLLYASTVGESSAGVMLGXKELNLASNAIDRIEDGFFSRMDK 221

Query: 194 LTTLYLRFNRITTVEKDI-----KNLPKLSMLSIRENKIKQLPAEIGELCNLITLDVAHN 248
           LTTL L  N ++ V +       ++L  L + +   NK+  L  +   L  + TL +AHN
Sbjct: 220 LTTLNLSDNHLSQVTQTTFSGLAQSLSTLDLSNTSLNKVHNLGFQ--SLQQIRTLKLAHN 47

Query: 249 QL 250
            L
Sbjct: 46  DL 41
>17298
          Length = 476

 Score = 34.7 bits (78), Expect = 0.095,   Method: Compositional matrix adjust.
 Identities = 16/39 (41%), Positives = 26/39 (66%)
 Frame = +3

Query: 225 NKIKQLPAEIGELCNLITLDVAHNQLEHLPKEIGNCTQI 263
           N I  +PA++  L +L  L++A NQ+E LP E+  CT++
Sbjct: 267 NAITDVPADLSSLPHLNCLNLADNQIEELPNELCECTRL 383

 Score = 34.7 bits (78), Expect = 0.098,   Method: Compositional matrix adjust.
 Identities = 19/54 (35%), Positives = 34/54 (62%)
 Frame = +3

Query: 430 LILSNNLLKKLPHGLGNLRKLRELDLEENKLESLPNEIAYLKDLQKLVLTNNQL 483
           +I +NN +  +P  L +L  L  L+L +N++E LPNE+     L++L L+ N++
Sbjct: 252 IIANNNAITDVPADLSSLPHLNCLNLADNQIEELPNELCECTRLKELKLSGNKI 413

 Score = 31.6 bits (70), Expect = 0.97,   Method: Compositional matrix adjust.
 Identities = 18/65 (27%), Positives = 34/65 (52%)
 Frame = +3

Query: 374 IFSRAKVLSKLNMKDNQLTSLPLDFGTWTSMVELNLATNQLTKIPEDVSGLVSLEVLILS 433
           + ++    S +   +N +T +P D  +   +  LNLA NQ+ ++P ++     L+ L LS
Sbjct: 222 VLAKCLTGSDIIANNNAITDVPADLSSLPHLNCLNLADNQIEELPNELCECTRLKELKLS 401

Query: 434 NNLLK 438
            N +K
Sbjct: 402 GNKIK 416
>14078
          Length = 1045

 Score = 33.1 bits (74), Expect = 0.35,   Method: Compositional matrix adjust.
 Identities = 30/99 (30%), Positives = 48/99 (48%), Gaps = 6/99 (6%)
 Frame = -1

Query: 395 PLDFGTWTSMVELNLATNQLTKIPEDVSG------LVSLEVLILSNNLLKKLPHGLGNLR 448
           P D+  W  +V     T+  T      +G      L   + L+L+ N++K++  GLG   
Sbjct: 460 PGDWSGWHQVV-----TSPYTGAQRQ*TGDYRWYLLTQHQKLVLAANVIKRIE-GLGRCA 299

Query: 449 KLRELDLEENKLESLPNEIAYLKDLQKLVLTNNQLSTLP 487
            L  L L +N+LESL      LK+LQ + L  N +S++ 
Sbjct: 298 GLTTLHLRDNQLESLDGFTDDLKELQYVNLRGNLMSSVK 182
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|61098122|ref|NP_080853.2| ADP-ribosylation
factor-like 13B [Mus musculus]
         (427 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

09827                                                                  98   6e-21
08153                                                                  96   2e-20
11378                                                                  94   1e-19
18208                                                                  90   2e-18
33605                                                                  84   9e-17
10862                                                                  74   4e-16
18949                                                                  74   1e-13
32860                                                                  60   2e-09
15973                                                                  53   2e-07
34468                                                                  47   1e-05
01398                                                                  38   0.006
26083                                                                  36   0.029
11965                                                                  35   0.081
06991                                                                  32   0.44 
19506                                                                  30   1.4  
29196                                                                  28   9.0  
>09827
          Length = 1201

 Score = 98.2 bits (243), Expect = 6e-21,   Method: Compositional matrix adjust.
 Identities = 56/163 (34%), Positives = 89/163 (54%)
 Frame = -3

Query: 24   LVMVGLDNAGKTATAKGIQGEHPEDVAPTVGFSKIDLRQGKFQVTIFDLGGGKRIRGIWK 83
            ++MVGLD AGKT     ++        PT+GF+   +       T++D+GG  +IR +W+
Sbjct: 1106 ILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNISFTVWDVGGQDKIRPLWR 927

Query: 84   NYYAESYGVIFVVDSSDEERMEETKETMSEVLRHPRISGKPILVLANKQDKEGALGEADV 143
            +Y+  + G+IFVVDS+D+ER++E +E ++ +L    +    +LV ANKQD   A+  A++
Sbjct: 926  HYFQNTQGLIFVVDSNDKERVQEAREELTRMLNEDELRDAVLLVFANKQDLPHAMATAEI 747

Query: 144  IECLSLEKLVNEHKCLCQIEPCSAVLGYGKKIDKSIKKGLYWL 186
             E L L  L N       I+   A  G G      + +GL WL
Sbjct: 746  TEKLGLHGLRNRT---WYIQSTCATTGDG------LYEGLDWL 645
>08153
          Length = 1703

 Score = 96.3 bits (238), Expect = 2e-20,   Method: Compositional matrix adjust.
 Identities = 54/150 (36%), Positives = 82/150 (54%)
 Frame = +1

Query: 3   SLMANCCNLFKRWREPVRKVTLVMVGLDNAGKTATAKGIQGEHPEDVAPTVGFSKIDLRQ 62
           S M    +LFK      ++V ++MVGLD AGKT     ++        PT+GF+   +  
Sbjct: 31  STMGGFVSLFKNLFGK-KEVRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEY 207

Query: 63  GKFQVTIFDLGGGKRIRGIWKNYYAESYGVIFVVDSSDEERMEETKETMSEVLRHPRISG 122
                T++D+GG  +IR +W++Y+  + G+IFVVDS+D ER+ E KE ++ +L    +  
Sbjct: 208 KNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERINEAKEELARMLNEDDLRD 387

Query: 123 KPILVLANKQDKEGALGEADVIECLSLEKL 152
             ILV ANKQD   A   ++V   L L  L
Sbjct: 388 AIILVFANKQDLPNAYSASEVTAHLGLANL 477
>11378
          Length = 1688

 Score = 93.6 bits (231), Expect = 1e-19,   Method: Compositional matrix adjust.
 Identities = 47/131 (35%), Positives = 72/131 (54%)
 Frame = +3

Query: 24  LVMVGLDNAGKTATAKGIQGEHPEDVAPTVGFSKIDLRQGKFQVTIFDLGGGKRIRGIWK 83
           LV +GLDNAGKT     ++ +      PT+  +  +L  G  + T FDLGG ++ R +WK
Sbjct: 330 LVFLGLDNAGKTTLLHMLKDDKMAQHVPTLHPTSEELSMGGMRFTTFDLGGHRQARRVWK 509

Query: 84  NYYAESYGVIFVVDSSDEERMEETKETMSEVLRHPRISGKPILVLANKQDKEGALGEADV 143
           +Y+    G++F+VD  D ER+ E K  +  ++   +++  PILVL NK DK GA  E ++
Sbjct: 510 DYFPAVDGIVFLVDVHDRERLVEAKAELDSLMTDEQVANAPILVLGNKIDKPGAASEEEI 689

Query: 144 IECLSLEKLVN 154
                L  L  
Sbjct: 690 RHWFGLNSLTT 722
>18208
          Length = 458

 Score = 89.7 bits (221), Expect = 2e-18,   Method: Compositional matrix adjust.
 Identities = 39/90 (43%), Positives = 62/90 (68%)
 Frame = -1

Query: 18  PVRKVTLVMVGLDNAGKTATAKGIQGEHPEDVAPTVGFSKIDLRQGKFQVTIFDLGGGKR 77
           P R++ ++++GLDNAGKT   K +  E P  + PT GF+   ++   F++ ++D+GG +R
Sbjct: 311 PDRELRILLLGLDNAGKTTLLKQLASEDPSHITPTQGFNIKSVQSKGFKLNVWDIGGQRR 132

Query: 78  IRGIWKNYYAESYGVIFVVDSSDEERMEET 107
           IR  WKNY+  +  +I+V+DSSD +RMEET
Sbjct: 131 IRPYWKNYFENTDLLIYVIDSSDTKRMEET 42
>33605
          Length = 888

 Score = 84.3 bits (207), Expect = 9e-17,   Method: Compositional matrix adjust.
 Identities = 36/98 (36%), Positives = 65/98 (66%)
 Frame = +1

Query: 11  LFKRWREPVRKVTLVMVGLDNAGKTATAKGIQGEHPEDVAPTVGFSKIDLRQGKFQVTIF 70
           + K+ ++  ++V L+M+GLDNAGKT   K   GE  + ++PT+GF+   L    F++ ++
Sbjct: 466 ILKKMKQKEKEVRLLMLGLDNAGKTTILKKFNGEDIDTISPTLGFNIKTLEHRGFKLNVW 645

Query: 71  DLGGGKRIRGIWKNYYAESYGVIFVVDSSDEERMEETK 108
           D+GG + +R  W+NY+  + G+++VVDS+D  R+ + K
Sbjct: 646 DVGGQQSLRSYWRNYFESTDGLVWVVDSADRMRIADCK 759
>10862
          Length = 2896

 Score = 73.9 bits (180), Expect(2) = 4e-16,   Method: Compositional matrix adjust.
 Identities = 41/134 (30%), Positives = 73/134 (54%), Gaps = 3/134 (2%)
 Frame = -3

Query: 56   SKIDLRQGKFQ---VTIFDLGGGKRIRGIWKNYYAESYGVIFVVDSSDEERMEETKETMS 112
            S+I  R  + Q     ++D+GG  +IR +W++YY  + G+IFVVD +D +R++E ++ + 
Sbjct: 2522 SRIQCRNCQLQECQFNVWDVGGQDKIRPLWRHYYTGTQGLIFVVDCADRDRIDEARQELH 2343

Query: 113  EVLRHPRISGKPILVLANKQDKEGALGEADVIECLSLEKLVNEHKCLCQIEPCSAVLGYG 172
             ++    +    IL+ ANKQD   A+   ++ E L L +L + +     ++P  A  G G
Sbjct: 2342 RIINDREMRDAIILIFANKQDLPDAMKPHEIQEKLGLTRLRDRNW---YVQPSCATTGDG 2172

Query: 173  KKIDKSIKKGLYWL 186
                  + +GL WL
Sbjct: 2171 ------LCEGLTWL 2148

 Score = 28.1 bits (61), Expect(2) = 4e-16,   Method: Compositional matrix adjust.
 Identities = 17/60 (28%), Positives = 29/60 (48%), Gaps = 6/60 (10%)
 Frame = -1

Query: 3    SLMANCCNLFKRWREPVRKVT------LVMVGLDNAGKTATAKGIQGEHPEDVAPTVGFS 56
            +++A C N      + + K+       ++M+GLD AGKT     ++        PTVGF+
Sbjct: 2689 TVLAGCTN*HITMGKLLSKIFGNKEMRILMLGLDAAGKTTLLYKMKLGQSVTXIPTVGFN 2510
>18949
          Length = 414

 Score = 73.9 bits (180), Expect = 1e-13,   Method: Composition-based stats.
 Identities = 33/80 (41%), Positives = 49/80 (61%)
 Frame = +3

Query: 59  DLRQGKFQVTIFDLGGGKRIRGIWKNYYAESYGVIFVVDSSDEERMEETKETMSEVLRHP 118
           +L  G    T FDLGG ++ R +WK+Y+    G++F+VD  D ER+ E K  +  +LR  
Sbjct: 39  ELSMGGMTFTTFDLGGHRQARRVWKDYFPAVDGIVFIVDVHDTERITEAKAELDSLLRDD 218

Query: 119 RISGKPILVLANKQDKEGAL 138
           +I+  P+LVL NK DK G +
Sbjct: 219 QIADIPVLVLGNKMDKHGVV 278
>32860
          Length = 330

 Score = 60.1 bits (144), Expect = 2e-09,   Method: Composition-based stats.
 Identities = 32/91 (35%), Positives = 50/91 (54%)
 Frame = +2

Query: 82  WKNYYAESYGVIFVVDSSDEERMEETKETMSEVLRHPRISGKPILVLANKQDKEGALGEA 141
           W  YY+ S  +I V+DS+D ER+  TKE +  +L    +    +LV ANKQD +G +  A
Sbjct: 8   WNTYYSNSEFIIMVIDSTDRERLSITKEELCRMLATEELRXAALLVFANKQDIKGCMSAA 187

Query: 142 DVIECLSLEKLVNEHKCLCQIEPCSAVLGYG 172
           ++   L+L   V +H  +  I+ C  + G G
Sbjct: 188 EISXQLNLTS-VKDH--VWHIQACCGLTGEG 271
>15973
          Length = 493

 Score = 53.1 bits (126), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 21/68 (30%), Positives = 46/68 (67%)
 Frame = -1

Query: 91  GVIFVVDSSDEERMEETKETMSEVLRHPRISGKPILVLANKQDKEGALGEADVIECLSLE 150
            ++++VD++D++++E ++  +  +L  P++ G P+LVL NK+D  GAL E ++I+ ++L 
Sbjct: 469 AIVYMVDAADQDKLEASRNELHNLLDKPQLQGVPVLVLGNKRDLPGALDEKELIDRMNLS 290

Query: 151 KLVNEHKC 158
            + +   C
Sbjct: 289 AIQDREIC 266
>34468
          Length = 1502

 Score = 47.0 bits (110), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 33/123 (26%), Positives = 56/123 (45%), Gaps = 9/123 (7%)
 Frame = +1

Query: 20  RKVTLVMVGLDNAGKTA-TAKGIQGEHPEDVAPTVGFSKIDLRQGKFQV-------TIFD 71
           R   ++++G  N GKT  T +   G+ P+    T+G   +D R+   QV        ++D
Sbjct: 490 RIFKIIVIGDSNVGKTCLTYRFCLGKFPDKTEATIG---VDFREKSIQVDSEHLKLQLWD 660

Query: 72  LGGGKRIR-GIWKNYYAESYGVIFVVDSSDEERMEETKETMSEVLRHPRISGKPILVLAN 130
             G +R R  + ++YY   + V+FV D +     E     + E  RH      P +++ N
Sbjct: 661 TAGQERFRKSMVQHYYRNVHAVVFVYDMTKMSSFENMPAWIEECDRHNLTKYIPRILVGN 840

Query: 131 KQD 133
           K D
Sbjct: 841 KCD 849
>01398
          Length = 1421

 Score = 38.1 bits (87), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 22/62 (35%), Positives = 29/62 (46%)
 Frame = -2

Query: 76   KRIRGIWKNYYAESYGVIFVVDSSDEERMEETKETMSEVLRHPRISGKPILVLANKQDKE 135
            +R R I ++YY  S GVI V D +     E  K+   E   H        LVL +K D+E
Sbjct: 1417 ERFRSITRSYYRNSVGVIIVYDITKRSTFENLKQWYEEARNHIEPHKAIFLVLGHKSDRE 1238

Query: 136  GA 137
             A
Sbjct: 1237 DA 1232
>26083
          Length = 432

 Score = 36.2 bits (82), Expect = 0.029,   Method: Compositional matrix adjust.
 Identities = 28/119 (23%), Positives = 54/119 (45%), Gaps = 5/119 (4%)
 Frame = +1

Query: 18  PVRKVTLVMVGLDNAGKTA-TAKGIQGEHPEDVAPTVGFSKID----LRQGKFQVTIFDL 72
           P+RK  LV +G  + GKT+   + +          T+G   +     L     ++ ++D 
Sbjct: 67  PLRKFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTIRLQLWDT 246

Query: 73  GGGKRIRGIWKNYYAESYGVIFVVDSSDEERMEETKETMSEVLRHPRISGKPILVLANK 131
            G +R R +  +Y  +S   + V D ++     +T + + +V R  R S   I+++ NK
Sbjct: 247 AGQERFRSLIPSYIRDSSVAVVVYDITNANSFHQTSKWIDDV-RTERGSDVIIMLVGNK 420
>11965
          Length = 3256

 Score = 34.7 bits (78), Expect = 0.081,   Method: Compositional matrix adjust.
 Identities = 19/94 (20%), Positives = 39/94 (41%), Gaps = 10/94 (10%)
 Frame = +1

Query: 50  APTVGFSKIDLRQGKFQVTIFDLGGGKRIRGIWKNYYAESYGVIFVVDSSDEE------- 102
             T G  ++          +FD+GG +  R  W + + +   +IF V  S+ +       
Sbjct: 139 VKTTGIVEVHFSFKNLNFKLFDVGGQRSERKKWIHCFEDVTAIIFCVAMSEYDQVLHEDE 318

Query: 103 ---RMEETKETMSEVLRHPRISGKPILVLANKQD 133
              RM+E+ +    +  +   +   I++  NK+D
Sbjct: 319 TTNRMQESLKLFDSICNNKWFTDTSIILFLNKKD 420
>06991
          Length = 1860

 Score = 32.0 bits (71), Expect = 0.44,   Method: Compositional matrix adjust.
 Identities = 25/78 (32%), Positives = 35/78 (44%)
 Frame = -2

Query: 115  LRHPRISGKPILVLANKQDKEGALGEADVIECLSLEKLVNEHKCLCQIEPCSAVLGYGKK 174
            L    +    ++V ANKQD EGA+   +V   L L  L N      QI   SAV G G  
Sbjct: 1859 LEEDELKKSILMVFANKQDIEGAMTVTEVANSLGLPGLKNRK---YQIFKTSAVKGEG-- 1695

Query: 175  IDKSIKKGLYWLLHIIAK 192
                + + + WL + + K
Sbjct: 1694 ----LDEAMEWLSNSLTK 1653
>19506
          Length = 421

 Score = 30.4 bits (67), Expect = 1.4,   Method: Composition-based stats.
 Identities = 16/48 (33%), Positives = 25/48 (52%)
 Frame = -3

Query: 9   CNLFKRWREPVRKVTLVMVGLDNAGKTATAKGIQGEHPEDVAPTVGFS 56
           C LF++     + VT++  GLD AGKT     ++        PT+GF+
Sbjct: 158 CTLFRQ-----KPVTVIYFGLDAAGKTTLLYNLKLGEVVTTIPTIGFN 30
>29196
          Length = 431

 Score = 27.7 bits (60), Expect = 9.0,   Method: Compositional matrix adjust.
 Identities = 15/51 (29%), Positives = 28/51 (54%), Gaps = 3/51 (5%)
 Frame = -2

Query: 69  IFDLGGGKRIRGIWKNYYAESYGVIFVVDSSDEERM---EETKETMSEVLR 116
           +FD+GG +  R  W + + +   +IF V  S+ +++   +ET   M E L+
Sbjct: 211 LFDVGGQRSERKKWIHCFEDVTAIIFCVAMSEYDQVLHEDETTNRMQESLK 59
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|7305339|ref|NP_038643.1| outer dense fiber of sperm
tails 2 isoform c [Mus musculus]
         (638 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

14387                                                                  99   6e-21
38550                                                                  31   1.6  
26175                                                                  30   3.2  
>14387
          Length = 910

 Score = 99.0 bits (245), Expect = 6e-21,   Method: Compositional matrix adjust.
 Identities = 57/151 (37%), Positives = 91/151 (60%)
 Frame = +1

Query: 469 DSLVERLHRQTAEYSAFKLENERLKASFAPMEDKLNQAHLEVQQLKASVKNYEGMIDNYK 528
           +SL  RLH + AE ++ KLENERLK+S A  E +L     E   L++S+ + E + D +K
Sbjct: 184 ESLTARLHDKCAEVTSLKLENERLKSSAASTESRLKSLEEESSHLRSSLHHSEHLADEFK 363

Query: 529 SQVMKTRLEADEVAAQLERCDKENKMLKDEMNKEIEAARRQFQSQLADLQQLPDILKITE 588
            Q+ ++R EADE    LE   KE   L+     E+E  + +   +L +L+ LP++L+ TE
Sbjct: 364 GQMDRSRREADESMVLLEEHQKETSRLQHSSEMELEKVKVRLHQRLQELEPLPELLRTTE 543

Query: 589 AKLAECQDQLQGYERKNIDLTAIISDLRSRV 619
            +L E  ++L  YER+N D T +I++L ++V
Sbjct: 544 LRLHEANEKLLQYERRNSDNTKLIAELTAKV 636
>38550
          Length = 438

 Score = 30.8 bits (68), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 16/45 (35%), Positives = 27/45 (60%)
 Frame = +3

Query: 334 LRCKEAENSRLCMQIKNLERSGNQHKAEVEAIMEQLKELKQKGDR 378
           ++C E  NS+L  +I+ LER  N+HK+E+  +   L + K+   R
Sbjct: 39  VQCAEDHNSKLQAKIQELERVMNEHKSELSTLRAALHQNKRSAGR 173
>26175
          Length = 409

 Score = 30.0 bits (66), Expect = 3.2,   Method: Compositional matrix adjust.
 Identities = 18/65 (27%), Positives = 34/65 (52%)
 Frame = +1

Query: 502 KLNQAHLEVQQLKASVKNYEGMIDNYKSQVMKTRLEADEVAAQLERCDKENKMLKDEMNK 561
           +L    ++  Q  +S+ N +   +NY ++V   R+ A E AA ++R D       DE+ +
Sbjct: 79  QLQTPPIQSPQQPSSISNKQTK-NNYVTEVFVHRVGAGEKAASVDRTDGGEDTRLDELTR 255

Query: 562 EIEAA 566
            ++AA
Sbjct: 256 SLKAA 270
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|94390061|ref|XP_913185.2| PREDICTED: enthoprotin
isoform 3 [Mus musculus]
         (732 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

20172                                                                  99   7e-21
27508                                                                  39   0.008
>20172
          Length = 479

 Score = 99.0 bits (245), Expect = 7e-21,   Method: Compositional matrix adjust.
 Identities = 48/89 (53%), Positives = 60/89 (67%)
 Frame = +2

Query: 184 GSERVVTSAREHIYDLRSLENYHFVDEHGKDQGINIRQKVKELVEFAQXXXXXXXXXXXX 243
           GSERVVTS+REH+YDLR LE+Y F DE+GKDQG+N+R KVKEL+EF Q            
Sbjct: 2   GSERVVTSSREHLYDLRGLESYSFTDENGKDQGLNVRHKVKELIEFIQDDDRLREERKKA 181

Query: 244 XXXXXXYVGVSSDSVGGFRYNERYDPEPK 272
                 + GVSSD  GG +Y++RY  EP+
Sbjct: 182 KKNKDKFTGVSSDFHGGPKYSDRYGDEPR 268
>27508
          Length = 1285

 Score = 38.9 bits (89), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 21/47 (44%), Positives = 30/47 (63%)
 Frame = -1

Query: 576 ASKTLPSTWSDPSVNISLDNLLPGMQPSKPQQPSLNTMIQQQNMQQP 622
           A K +P+TW+D  V+I+LD L PG + +K   P++N M  QQN   P
Sbjct: 613 AQKGMPTTWTDTGVDINLDVLGPGGRQNKAATPTMNQM--QQNRPAP 479
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|157057145|ref|NP_848803.3| actin-binding LIM protein
1 isoform 1 [Mus musculus]
         (861 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

11928                                                                  99   8e-21
09680                                                                  84   3e-16
07437                                                                  67   4e-11
14307                                                                  64   3e-10
05726                                                                  61   2e-09
34420                                                                  51   2e-06
05103                                                                  43   5e-04
30169                                                                  41   0.002
26762                                                                  39   0.006
04349                                                                  36   0.078
03731                                                                  33   0.41 
27368                                                                  31   1.7  
01348                                                                  30   5.6  
39894                                                                  29   8.1  
38905                                                                  29   9.0  
04322                                                                  29   9.3  
>11928
          Length = 1623

 Score = 99.0 bits (245), Expect = 8e-21,   Method: Compositional matrix adjust.
 Identities = 69/213 (32%), Positives = 97/213 (45%), Gaps = 5/213 (2%)
 Frame = -2

Query: 99   CHKCGEPCKGEVLRVQTKHFHIKCFTCKVCGCDLAQGGFFIKNGDYLCTLDYQRMYGTRC 158
            C  C +P  G+V+    + +H++ F C  C   L    F+ ++    C +DY  ++  RC
Sbjct: 1598 CAACNKPIVGQVIAALGRTWHVEHFVCAHCEQPLGTSNFYERDSVAYCEVDYHNLFAPRC 1419

Query: 159  HGCGEFVEGEVVTALGKTYHPNCFACTICKRPFPPGDRVTFNG----RDCLCQLCAQPMS 214
              C   +  + +TAL K +HP  F C  C R F   D    NG    RD   Q+      
Sbjct: 1418 AYCNGPIVDKCITALEKMWHPEHFFCAQCGRQFGDEDFHEKNGKAYCRDDYFQM------ 1257

Query: 215  SSPKEASCSSNCAGCGRDIKNGQALLALDKQWHLGCFKCKSCGKVL-TGEYISKDGSPYC 273
             +PK       C GCG  I     + AL++QWH  CF C  C     TG +   DG PYC
Sbjct: 1256 FAPK-------CGGCGMPIMENY-ISALNRQWHPQCFCCWECQAPFGTGSFYDHDGLPYC 1101

Query: 274  EKDYQGLFGVKCEACHQFITGKVLEAGDKHYHP 306
            E  Y    G  C +C + ITG+ + A  K +HP
Sbjct: 1100 ETHYHAKKGSLCASCQKPITGRCITAMFKKFHP 1002

 Score = 71.2 bits (173), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 55/194 (28%), Positives = 84/194 (43%), Gaps = 1/194 (0%)
 Frame = -2

Query: 55   GTVIHLVYLYSAGCGPPELRFSSYD-PSVAHPQDPHHSSEKPVIHCHKCGEPCKGEVLRV 113
            G   H+ +   A C  P    + Y+  SVA+ +  +H+   P   C  C  P   + +  
Sbjct: 1550 GRTWHVEHFVCAHCEQPLGTSNFYERDSVAYCEVDYHNLFAP--RCAYCNGPIVDKCITA 1377

Query: 114  QTKHFHIKCFTCKVCGCDLAQGGFFIKNGDYLCTLDYQRMYGTRCHGCGEFVEGEVVTAL 173
              K +H + F C  CG       F  KNG   C  DY +M+  +C GCG  +    ++AL
Sbjct: 1376 LEKMWHPEHFFCAQCGRQFGDEDFHEKNGKAYCRDDYFQMFAPKCGGCGMPIMENYISAL 1197

Query: 174  GKTYHPNCFACTICKRPFPPGDRVTFNGRDCLCQLCAQPMSSSPKEASCSSNCAGCGRDI 233
             + +HP CF C  C+ PF  G     +G          P   +   A   S CA C + I
Sbjct: 1196 NRQWHPQCFCCWECQAPFGTGSFYDHDGL---------PYCETHYHAKKGSLCASCQKPI 1044

Query: 234  KNGQALLALDKQWH 247
              G+ + A+ K++H
Sbjct: 1043 -TGRCITAMFKKFH 1005

 Score = 70.5 bits (171), Expect = 3e-12,   Method: Compositional matrix adjust.
 Identities = 49/165 (29%), Positives = 72/165 (43%), Gaps = 1/165 (0%)
 Frame = -2

Query: 158  CHGCGEFVEGEVVTALGKTYHPNCFACTICKRPFPPGDRVTFNGRDCLCQLCAQPMSSSP 217
            C  C + + G+V+ ALG+T+H   F C  C++P    +   F  RD      +       
Sbjct: 1598 CAACNKPIVGQVIAALGRTWHVEHFVCAHCEQPLGTSN---FYERD------SVAYCEVD 1446

Query: 218  KEASCSSNCAGCGRDIKNGQALLALDKQWHLGCFKCKSCGKVLTGE-YISKDGSPYCEKD 276
                 +  CA C   I + + + AL+K WH   F C  CG+    E +  K+G  YC  D
Sbjct: 1445 YHNLFAPRCAYCNGPIVD-KCITALEKMWHPEHFFCAQCGRQFGDEDFHEKNGKAYCRDD 1269

Query: 277  YQGLFGVKCEACHQFITGKVLEAGDKHYHPSCARCSRCNQMFTEG 321
            Y  +F  KC  C   I    + A ++ +HP C  C  C   F  G
Sbjct: 1268 YFQMFAPKCGGCGMPIMENYISALNRQWHPQCFCCWECQAPFGTG 1134

 Score = 44.7 bits (104), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 24/85 (28%), Positives = 36/85 (42%)
 Frame = -2

Query: 99   CHKCGEPCKGEVLRVQTKHFHIKCFTCKVCGCDLAQGGFFIKNGDYLCTLDYQRMYGTRC 158
            C  CG P     +    + +H +CF C  C      G F+  +G   C   Y    G+ C
Sbjct: 1244 CGGCGMPIMENYISALNRQWHPQCFCCWECQAPFGTGSFYDHDGLPYCETHYHAKKGSLC 1065

Query: 159  HGCGEFVEGEVVTALGKTYHPNCFA 183
              C + + G  +TA+ K +HP  F 
Sbjct: 1064 ASCQKPITGRCITAMFKKFHPEHFC 990
>09680
          Length = 878

 Score = 83.6 bits (205), Expect = 3e-16,   Method: Compositional matrix adjust.
 Identities = 51/161 (31%), Positives = 76/161 (47%), Gaps = 2/161 (1%)
 Frame = -2

Query: 157 RCHGCGEFVEGEVVTALGKTYHPNCFACTICKRPFPPGDRVTFNGRDCLCQLCAQPMSSS 216
           +CH C E +   VV ALGK YHP  F C  C +         FN +        +P+ ++
Sbjct: 718 QCHKCNEAITSRVVFALGKNYHPEHFLCRDCDKQIKDD---IFNIQQ------GEPVCNA 566

Query: 217 PKEASCSSNCAGCGRDIKNGQALLALDKQWHLGCFKCKSCGK--VLTGEYISKDGSPYCE 274
                 +S CAGC   I +G  + A+   WH  CF C    K  +    +  ++G  YC 
Sbjct: 565 CYLERYTSTCAGCKEPI-HGTTISAMGNNWHEHCFVCDGACKQPLKDSSFFEREGKAYCR 389

Query: 275 KDYQGLFGVKCEACHQFITGKVLEAGDKHYHPSCARCSRCN 315
           +DY+ LF V+C  C + IT   + A +  +H  C  C+RC+
Sbjct: 388 QDYEDLFAVRCAKCEKPITENAIVAMNAKWHSDCFCCNRCD 266

 Score = 70.9 bits (172), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 51/182 (28%), Positives = 79/182 (43%), Gaps = 2/182 (1%)
 Frame = -2

Query: 94  KPVIHCHKCGEPCKGEVLRVQTKHFHIKCFTCKVCGCDLAQGGFFIKNGDYLCTLDYQRM 153
           K    CHKC E     V+    K++H + F C+ C   +    F I+ G+ +C   Y   
Sbjct: 730 KQQYQCHKCNEAITSRVVFALGKNYHPEHFLCRDCDKQIKDDIFNIQQGEPVCNACYLER 551

Query: 154 YGTRCHGCGEFVEGEVVTALGKTYHPNCFACT-ICKRPFPPGDRVTFNGRDCLCQLCAQP 212
           Y + C GC E + G  ++A+G  +H +CF C   CK+P          G+      C Q 
Sbjct: 550 YTSTCAGCKEPIHGTTISAMGNNWHEHCFVCDGACKQPLKDSSFFEREGK----AYCRQD 383

Query: 213 MSSSPKEASCSSNCAGCGRDIKNGQALLALDKQWHLGCFKCKSCGK-VLTGEYISKDGSP 271
                 E   +  CA C + I    A++A++ +WH  CF C  C   + T  +  +   P
Sbjct: 382 Y-----EDLFAVRCAKCEKPITEN-AIVAMNAKWHSDCFCCNRCDNPIKTKTFTIEGDKP 221

Query: 272 YC 273
            C
Sbjct: 220 IC 215
>07437
          Length = 951

 Score = 66.6 bits (161), Expect = 4e-11,   Method: Compositional matrix adjust.
 Identities = 64/213 (30%), Positives = 88/213 (41%), Gaps = 10/213 (4%)
 Frame = +3

Query: 111 LRVQTKHFHIKCFTCKVCGCDLAQGGFFIKNGDYLC--TLDYQRMYGT---RCHGCGEFV 165
           ++     +H +CF C++CG  +A  GF    G  LC      ++  GT    CH C + +
Sbjct: 3   IKAMNSAWHPQCFLCQLCGTCMADSGFVKNAGRALCRECNAKEKARGTGKYVCHKCHDVI 182

Query: 166 EGEV-VTALGKTYHPNCFACTICKRPFPPGDRVTFNGRDCLCQLCAQPMSSSPKEASCSS 224
           E    +   G+ YHP  F C  C        R   +   CL   C   M           
Sbjct: 183 EMNGHIKFRGEAYHPYHFNCHSCGVELNTEAREKDSELYCL--RCHDKMGIPI------- 335

Query: 225 NCAGCGRDIKNGQALLALDKQWHLGCFKCKSCGKVLTG-EYISKDGSPYCEKDYQGLFGV 283
            C  C R I+  + + AL K WH+  F C  C K   G  +  K G  YCE  Y  LFG 
Sbjct: 336 -CGACRRPIEE-RVVHALGKAWHVEHFVCAKCEKPFLGTRHYEKKGLAYCEIHYHQLFGN 509

Query: 284 KCEACHQFITGKVLEAGDKHY---HPSCARCSR 313
            C  C+  I G V  A +K +   H +C+ C R
Sbjct: 510 ICFVCNNIINGDVFSAFNKAWCVHHFACSICDR 608

 Score = 45.1 bits (105), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 26/91 (28%), Positives = 42/91 (46%)
 Frame = +3

Query: 99  CHKCGEPCKGEVLRVQTKHFHIKCFTCKVCGCDLAQGGFFIKNGDYLCTLDYQRMYGTRC 158
           C  C  P +  V+    K +H++ F C  C         + K G   C + Y +++G  C
Sbjct: 336 CGACRRPIEERVVHALGKAWHVEHFVCAKCEKPFLGTRHYEKKGLAYCEIHYHQLFGNIC 515

Query: 159 HGCGEFVEGEVVTALGKTYHPNCFACTICKR 189
             C   + G+V +A  K +  + FAC+IC R
Sbjct: 516 FVCNNIINGDVFSAFNKAWCVHHFACSICDR 608

 Score = 43.5 bits (101), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 38/149 (25%), Positives = 59/149 (39%)
 Frame = +3

Query: 170 VTALGKTYHPNCFACTICKRPFPPGDRVTFNGRDCLCQLCAQPMSSSPKEASCSSNCAGC 229
           + A+   +HP CF C +C         V   GR     LC +  +      +    C  C
Sbjct: 3   IKAMNSAWHPQCFLCQLCGTCMADSGFVKNAGR----ALCRECNAKEKARGTGKYVCHKC 170

Query: 230 GRDIKNGQALLALDKQWHLGCFKCKSCGKVLTGEYISKDGSPYCEKDYQGLFGVKCEACH 289
              I+    +    + +H   F C SCG  L  E   KD   YC + +  +    C AC 
Sbjct: 171 HDVIEMNGHIKFRGEAYHPYHFNCHSCGVELNTEAREKDSELYCLRCHDKMGIPICGACR 350

Query: 290 QFITGKVLEAGDKHYHPSCARCSRCNQMF 318
           + I  +V+ A  K +H     C++C + F
Sbjct: 351 RPIEERVVHALGKAWHVEHFVCAKCEKPF 437

 Score = 38.5 bits (88), Expect = 0.010,   Method: Compositional matrix adjust.
 Identities = 40/157 (25%), Positives = 62/157 (39%), Gaps = 2/157 (1%)
 Frame = +3

Query: 123 FTCKVCGCDLAQGGFFIKNGDYLCTLDYQRMYGTRCHGCGEFVEGEVVTALGKTYHPNCF 182
           F C  CG +L       K+ +  C   + +M    C  C   +E  VV ALGK +H   F
Sbjct: 234 FNCHSCGVELNTEAR-EKDSELYCLRCHDKMGIPICGACRRPIEERVVHALGKAWHVEHF 410

Query: 183 ACTICKRPFPPGDRVTFNGRDCLCQLCAQPMSSSPKEASCSSNCAGCGRDIKNGQALLAL 242
            C  C++PF         G    C++    +  +         C  C  +I NG    A 
Sbjct: 411 VCAKCEKPFLGTRHYEKKGLA-YCEIHYHQLFGNI--------CFVCN-NIINGDVFSAF 560

Query: 243 DKQWHLGCFKCKSCGKVLT--GEYISKDGSPYCEKDY 277
           +K W +  F C  C + ++   ++   D  P C+  Y
Sbjct: 561 NKAWCVHHFACSICDRKMSQKTKFFEFDQKPVCKNCY 671
>14307
          Length = 816

 Score = 63.9 bits (154), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 52/176 (29%), Positives = 78/176 (44%), Gaps = 11/176 (6%)
 Frame = +2

Query: 156 TRCHGC-GEFVEGEVVTAL-----GKTYHPNCFACTICKRPFPPGDRVTFNGRDCLCQLC 209
           T CH C GE  + E+V        G  +HP CF C+ C+      D V        CQ  
Sbjct: 173 TTCHCCKGEIDKLELVVTAPKVGEGTVWHPACFVCSTCEELLV--DLV-------YCQHD 325

Query: 210 AQPMSSSPKEASCSSNCAGCGRDIKNGQALLALDKQWH---LGCFKCKSCGKVLTGEYIS 266
                           C GC   I +G+   A+++ +H   L C++C    ++++  YI 
Sbjct: 326 KHLYCQRHYAELIRPRCPGCDELIFSGEYTKAMEECYHKDHLACWQCDK--QLVSCRYIM 499

Query: 267 KDGSPYCEKDYQGLFGVKCEACHQFI--TGKVLEAGDKHYHPSCARCSRCNQMFTE 320
           +D  P+C   YQ LF  KCE C + I    K L   DKH+H  C +C+ C++   +
Sbjct: 500 RDDHPHCVPCYQALFANKCEDCDKPIGPDYKDLSYKDKHWHEFCFKCTMCDKSLVD 667

 Score = 60.8 bits (146), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 56/218 (25%), Positives = 84/218 (38%), Gaps = 15/218 (6%)
 Frame = +2

Query: 106 CKGEVLRVQT----------KHFHIKCFTCKVCGCDLAQGGFFIKNGDYLCTLDYQRMYG 155
           CKGE+ +++             +H  CF C  C   L    +   +    C   Y  +  
Sbjct: 188 CKGEIDKLELVVTAPKVGEGTVWHPACFVCSTCEELLVDLVYCQHDKHLYCQRHYAELIR 367

Query: 156 TRCHGCGEFV-EGEVVTALGKTYHPNCFACTICKRPFPPGDRVTFNGRDCLCQLCAQPMS 214
            RC GC E +  GE   A+ + YH +  AC  C +         +  RD        P  
Sbjct: 368 PRCPGCDELIFSGEYTKAMEECYHKDHLACWQCDKQLVS---CRYIMRD------DHPHC 520

Query: 215 SSPKEASCSSNCAGCGRDIK-NGQALLALDKQWHLGCFKCKSCGKVLTGE-YISKDGSPY 272
               +A  ++ C  C + I  + + L   DK WH  CFKC  C K L  + +  K+   +
Sbjct: 521 VPCYQALFANKCEDCDKPIGPDYKDLSYKDKHWHEFCFKCTMCDKSLVDQPFAPKNEKIF 700

Query: 273 CEKDYQGLFGVKCEACHQFITG--KVLEAGDKHYHPSC 308
           C + Y   F  +C+ C     G  K  E   K +H  C
Sbjct: 701 CSECYDNSFAARCDGCGNPFKGGMKKFEYKGKQWHDEC 814
>05726
          Length = 733

 Score = 60.8 bits (146), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 35/99 (35%), Positives = 48/99 (48%), Gaps = 5/99 (5%)
 Frame = +1

Query: 246 WHLGCFKCKSCGKVLTGE-YISKDGSPYCEKDYQGLFGVKCEACHQFITG----KVLEAG 300
           WH  CF C  C K+L GE + SKD  PYC   +  LF  KC  C + ITG    K +   
Sbjct: 130 WHRECFTCTHCDKMLAGEKFTSKDDQPYCGDCFGDLFAKKCCRCQKAITGIGGTKFISFE 309

Query: 301 DKHYHPSCARCSRCNQMFTEGEEMYLQGSTVWHPDCKQS 339
           ++H+H  C  C +C Q    G    +    +  PDC ++
Sbjct: 310 ERHWHSDCFTCFKC-QASMVGRGFLMNDDDIVCPDCGRT 423

 Score = 34.7 bits (78), Expect = 0.15,   Method: Compositional matrix adjust.
 Identities = 30/133 (22%), Positives = 50/133 (37%), Gaps = 4/133 (3%)
 Frame = +1

Query: 145 LCTLDYQRMYGTRCHGCGEFVEGEVVTALGKTYHPNCFACTICKRPFPPGDRVTFNGRDC 204
           +C   Y+  Y  RC  C + +    ++     +H  CF CT C +    G++  F  +D 
Sbjct: 34  ICVPCYENNYAQRCFKCSQVINKGGISYKNTPWHRECFTCTHCDKML-AGEK--FTSKD- 201

Query: 205 LCQLCAQPMSSSPKEASCSSNCAGCGRDIK--NGQALLAL-DKQWHLGCFKCKSCGKVLT 261
                 QP          +  C  C + I    G   ++  ++ WH  CF C  C   + 
Sbjct: 202 -----DQPYCGDCFGDLFAKKCCRCQKAITGIGGTKFISFEERHWHSDCFTCFKCQASMV 366

Query: 262 GE-YISKDGSPYC 273
           G  ++  D    C
Sbjct: 367 GRGFLMNDDDIVC 405
>34420
          Length = 719

 Score = 50.8 bits (120), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 29/81 (35%), Positives = 40/81 (49%), Gaps = 4/81 (4%)
 Frame = +2

Query: 263 EYISKDGSPYCEKDYQGLFGVKCEACHQFITG----KVLEAGDKHYHPSCARCSRCNQMF 318
           ++ SKD  PYC   +  LF  +C  C Q ITG    K +   ++H+H  C  C RCN   
Sbjct: 5   KFTSKDEQPYCGDCFGELFAKRCIRCTQPITGIGGTKFISFEERHWHSDCFVCYRCNASM 184

Query: 319 TEGEEMYLQGSTVWHPDCKQS 339
             G    +QG  +  PDC +S
Sbjct: 185 V-GRGFLMQGEEILCPDCGRS 244

 Score = 29.3 bits (64), Expect = 7.1,   Method: Compositional matrix adjust.
 Identities = 14/52 (26%), Positives = 25/52 (48%), Gaps = 4/52 (7%)
 Frame = +2

Query: 99  CHKCGEPCKG----EVLRVQTKHFHIKCFTCKVCGCDLAQGGFFIKNGDYLC 146
           C +C +P  G    + +  + +H+H  CF C  C   +   GF ++  + LC
Sbjct: 71  CIRCTQPITGIGGTKFISFEERHWHSDCFVCYRCNASMVGRGFLMQGEEILC 226
>05103
          Length = 1504

 Score = 43.1 bits (100), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 15/58 (25%), Positives = 27/58 (46%)
 Frame = +2

Query: 89  HHSSEKPVIHCHKCGEPCKGEVLRVQTKHFHIKCFTCKVCGCDLAQGGFFIKNGDYLC 146
               ++P + C  C     G +++     +H+ CF C+ C  +L Q GFF+ +    C
Sbjct: 614 EQKQQQPSMRCGGCDMLATGVIVKANGVPYHVACFKCESCSMNLKQKGFFVVDDKLYC 787

 Score = 34.3 bits (77), Expect = 0.20,   Method: Compositional matrix adjust.
 Identities = 15/37 (40%), Positives = 17/37 (45%)
 Frame = +2

Query: 151 QRMYGTRCHGCGEFVEGEVVTALGKTYHPNCFACTIC 187
           Q+    RC GC     G +V A G  YH  CF C  C
Sbjct: 623 QQQPSMRCGGCDMLATGVIVKANGVPYHVACFKCESC 733

 Score = 32.0 bits (71), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 19/58 (32%), Positives = 27/58 (46%), Gaps = 1/58 (1%)
 Frame = +2

Query: 218 KEASCSSNCAGCGRDIKNGQALLALDKQWHLGCFKCKSCGKVLTGE-YISKDGSPYCE 274
           K+   S  C GC   +  G  + A    +H+ CFKC+SC   L  + +   D   YCE
Sbjct: 620 KQQQPSMRCGGCDM-LATGVIVKANGVPYHVACFKCESCSMNLKQKGFFVVDDKLYCE 790
>30169
          Length = 426

 Score = 41.2 bits (95), Expect = 0.002,   Method: Composition-based stats.
 Identities = 20/60 (33%), Positives = 32/60 (53%), Gaps = 1/60 (1%)
 Frame = -1

Query: 226 CAGCGRDIKNGQALLALDKQWHLGCFKCKSCGKVLTGEYISK-DGSPYCEKDYQGLFGVK 284
           CA CG+ +   + +  + K +H  CFKC SC K+L    +++   + YC+  Y   FG K
Sbjct: 405 CAVCGKAVYFAERVAGMGKVYHKACFKCTSCRKILDSTLLTQHQDNIYCKACYGKNFGPK 226

 Score = 34.7 bits (78), Expect = 0.16,   Method: Composition-based stats.
 Identities = 15/33 (45%), Positives = 19/33 (57%), Gaps = 1/33 (3%)
 Frame = -1

Query: 158 CHGCGEFVE-GEVVTALGKTYHPNCFACTICKR 189
           C  CG+ V   E V  +GK YH  CF CT C++
Sbjct: 405 CAVCGKAVYFAERVAGMGKVYHKACFKCTSCRK 307
>26762
          Length = 399

 Score = 39.3 bits (90), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 22/79 (27%), Positives = 36/79 (45%), Gaps = 4/79 (5%)
 Frame = +1

Query: 264 YISKDGSPYCEKDYQGLFGVKCEACHQFITG----KVLEAGDKHYHPSCARCSRCNQMFT 319
           + S+D  PYC +    LF  +C +C + ITG    + +   ++H+H  C  C+ C     
Sbjct: 7   FTSRDEKPYCAECLGELFAKRCTSCVKPITGIGGTRFISFEERHWHHDCFVCASCKASLV 186

Query: 320 EGEEMYLQGSTVWHPDCKQ 338
            G      G  +  PDC +
Sbjct: 187 -GRGFITDGPDILCPDCAK 240

 Score = 28.9 bits (63), Expect = 8.1,   Method: Compositional matrix adjust.
 Identities = 21/56 (37%), Positives = 24/56 (42%), Gaps = 4/56 (7%)
 Frame = +1

Query: 243 DKQWHLGCFKCKSCGKVLTGEYISKDG----SPYCEKDYQGLFGVKCEACHQFITG 294
           ++ WH  CF C SC   L G     DG     P C K  Q L    CE+    ITG
Sbjct: 130 ERHWHHDCFVCASCKASLVGRGFITDGPDILCPDCAK--QKLM*KSCESKAPKITG 291

 Score = 28.9 bits (63), Expect = 9.9,   Method: Compositional matrix adjust.
 Identities = 22/77 (28%), Positives = 28/77 (36%), Gaps = 4/77 (5%)
 Frame = +1

Query: 74  RFSSYDPSVAHPQDPHHSSEKPVIHCHKCGEPCKG----EVLRVQTKHFHIKCFTCKVCG 129
           RF+S D     P       E     C  C +P  G      +  + +H+H  CF C  C 
Sbjct: 4   RFTSRDEK---PYCAECLGELFAKRCTSCVKPITGIGGTRFISFEERHWHHDCFVCASCK 174

Query: 130 CDLAQGGFFIKNGDYLC 146
             L   GF     D LC
Sbjct: 175 ASLVGRGFITDGPDILC 225
>04349
          Length = 1161

 Score = 35.8 bits (81), Expect = 0.078,   Method: Compositional matrix adjust.
 Identities = 22/80 (27%), Positives = 34/80 (42%), Gaps = 4/80 (5%)
 Frame = +3

Query: 92  SEKPVIHCHKCGEPCKG----EVLRVQTKHFHIKCFTCKVCGCDLAQGGFFIKNGDYLCT 147
           S +  +   KCG   K     E + ++   +H  CF C  C C L    F I      CT
Sbjct: 201 SMRVAVQLEKCGACHKTVYAMEKIEIEKNAYHKSCFRCSHCHCVLTPKTFAINKNVMFCT 380

Query: 148 LDYQRMYGTRCHGCGEFVEG 167
             Y++++ T+    G + EG
Sbjct: 381 NHYKQLFATK----GNYDEG 428

 Score = 31.2 bits (69), Expect = 1.9,   Method: Compositional matrix adjust.
 Identities = 15/37 (40%), Positives = 21/37 (56%), Gaps = 1/37 (2%)
 Frame = +3

Query: 284 KCEACHQFITG-KVLEAGDKHYHPSCARCSRCNQMFT 319
           KC ACH+ +   + +E     YH SC RCS C+ + T
Sbjct: 228 KCGACHKTVYAMEKIEIEKNAYHKSCFRCSHCHCVLT 338

 Score = 31.2 bits (69), Expect = 1.9,   Method: Compositional matrix adjust.
 Identities = 18/72 (25%), Positives = 28/72 (38%), Gaps = 1/72 (1%)
 Frame = +3

Query: 214 SSSPKEASCSSNCAGCGRDIKNGQALLALDKQWHLGCFKCKSCGKVLT-GEYISKDGSPY 272
           S S + A     C  C + +   + +      +H  CF+C  C  VLT   +       +
Sbjct: 195 SKSMRVAVQLEKCGACHKTVYAMEKIEIEKNAYHKSCFRCSHCHCVLTPKTFAINKNVMF 374

Query: 273 CEKDYQGLFGVK 284
           C   Y+ LF  K
Sbjct: 375 CTNHYKQLFATK 410
>03731
          Length = 728

 Score = 33.5 bits (75), Expect = 0.41,   Method: Composition-based stats.
 Identities = 15/37 (40%), Positives = 21/37 (56%), Gaps = 1/37 (2%)
 Frame = +2

Query: 284 KCEACHQFITG-KVLEAGDKHYHPSCARCSRCNQMFT 319
           KC ACH+ +   + +E     YH SC RCS C+ + T
Sbjct: 584 KCGACHKTVYAMEKIEIEKNAYHKSCFRCSHCHCVLT 694
>27368
          Length = 394

 Score = 31.2 bits (69), Expect = 1.7,   Method: Composition-based stats.
 Identities = 19/44 (43%), Positives = 21/44 (47%), Gaps = 1/44 (2%)
 Frame = +1

Query: 203 DCLCQLCAQPMSSSPKEASCSSN-CAGCGRDIKNGQALLALDKQ 245
           D LCQLC QP+   P E  C    C  C +     QAL   DKQ
Sbjct: 1   DLLCQLCHQPL-VDPLETKCGHTFCTSCLKSHLAVQALCPEDKQ 129
>01348
          Length = 1616

 Score = 29.6 bits (65), Expect = 5.6,   Method: Composition-based stats.
 Identities = 14/33 (42%), Positives = 18/33 (54%), Gaps = 1/33 (3%)
 Frame = -3

Query: 101  KCGEPC-KGEVLRVQTKHFHIKCFTCKVCGCDL 132
            KC + C K      Q+K  H  CF C+ CGCD+
Sbjct: 1488 KCRDTCIKDFGFMAQSKEDHFSCF-CRACGCDV 1393
>39894
          Length = 458

 Score = 28.9 bits (63), Expect = 8.1,   Method: Compositional matrix adjust.
 Identities = 18/53 (33%), Positives = 25/53 (47%), Gaps = 2/53 (3%)
 Frame = +2

Query: 739 LPGYGKNGLHRPVS--TDFAQYNSYGDISGGVRDYQTLPDGHMPAVRMDRGVS 789
           LP  G+ G  +  S  T    Y  Y  +   +RD+ TLPD  + A  +D  VS
Sbjct: 278 LPSRGRRGHSQQFSLITGRTDYRKYSFLPRTIRDWNTLPDNVVEANTIDTLVS 436
>38905
          Length = 686

 Score = 28.9 bits (63), Expect = 9.0,   Method: Composition-based stats.
 Identities = 13/36 (36%), Positives = 20/36 (55%)
 Frame = -2

Query: 196 RVTFNGRDCLCQLCAQPMSSSPKEASCSSNCAGCGR 231
           RVTF  R   C   A   S++ ++++CS+NC    R
Sbjct: 337 RVTFTNRRLRCIRGASK*SAAAEDSACSANCQAGAR 230
>04322
          Length = 374

 Score = 28.9 bits (63), Expect = 9.3,   Method: Composition-based stats.
 Identities = 16/37 (43%), Positives = 22/37 (59%), Gaps = 1/37 (2%)
 Frame = -1

Query: 112 RVQTKHFHIKC-FTCKVCGCDLAQGGFFIKNGDYLCT 147
           +V+TK FH KC + C +C C   +    IKN DY C+
Sbjct: 329 KVKTKKFHFKCVYKCDIC*C*TIE----IKN-DYACS 234
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6755204|ref|NP_035316.1| proteasome (prosome,
macropain) subunit, beta type 5 [Mus musculus]
         (264 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

06516                                                                  97   8e-21
07622                                                                  76   2e-14
09425                                                                  64   6e-11
20771                                                                  55   4e-08
19360                                                                  51   6e-07
01337                                                                  47   1e-05
28971                                                                  30   1.4  
>06516
          Length = 835

 Score = 96.7 bits (239), Expect = 8e-21,   Method: Compositional matrix adjust.
 Identities = 59/207 (28%), Positives = 100/207 (48%), Gaps = 3/207 (1%)
 Frame = +1

Query: 55  EMLHGTTTLAFKFLHGVIVAADSRATAGAYIASQTVKKVIEINPYLLGTMAGGAADCSFW 114
           E+  GTT +A ++  GV++ ADSR T GAYIA++   K+ ++   +    +G AAD    
Sbjct: 109 EVTTGTTIMAVEYEDGVVIGADSRTTTGAYIANRVTDKLTKVTDRIYCCRSGSAADTQAI 288

Query: 115 ERLLARQCRIYELRNKERISVAAASKLLANMVYQYKGMGLSMGTMICGWDKRGPGLYYVD 174
             ++      Y +   E   V  A+ +   + Y  +   L+ G ++ GWDKR  G  Y  
Sbjct: 289 ADIVKYHLDFYRMEMGEEPQVQTAANVFRELCYDNRD-SLTAGIIVAGWDKRTGGQVYSV 465

Query: 175 SEGNRISGTAFSV-GSGSVYAYGVMDRGYSYDLKVEEAYDLARRAIYQATYRDAYSGGAV 233
             G  +    F++ GSGS Y YG +D  +   +K ++      +A+  A  RD  SGG +
Sbjct: 466 PIGGMLQRQPFAIGGSGSTYLYGYVDAQFKPSMKKDDCLKFVSQAVSLAINRDGSSGGII 645

Query: 234 NLYHVREDGWIRV--SSDNVADLHDKY 258
            +  + ++G  RV  + D +    + Y
Sbjct: 646 RMAVINKEGVERVTLTGDQLPKFFEDY 726
>07622
          Length = 2072

 Score = 75.9 bits (185), Expect = 2e-14,   Method: Compositional matrix adjust.
 Identities = 45/93 (48%), Positives = 59/93 (63%), Gaps = 8/93 (8%)
 Frame = -1

Query: 171  YYVDSEGNRISGTAFSVGSGSVYAYGVMDRGYSYDLKV--------EEAYDLARRAIYQA 222
            Y++DS  + + GT+ S    SV ++GV    +S  L V        EEAYDL +RAIY A
Sbjct: 1136 YFLDSSED-VHGTSTSRSRNSV-SFGVR-HFFSLVLDVFVPKYKSXEEAYDLGKRAIYHA 966

Query: 223  TYRDAYSGGAVNLYHVREDGWIRVSSDNVADLH 255
            T+RDAYSGG VNLYH++E GWI+ S  +  DLH
Sbjct: 965  THRDAYSGGVVNLYHMKETGWIKESQTDTQDLH 867
>09425
          Length = 1898

 Score = 63.9 bits (154), Expect = 6e-11,   Method: Compositional matrix adjust.
 Identities = 49/187 (26%), Positives = 86/187 (45%), Gaps = 3/187 (1%)
 Frame = -3

Query: 58   HGTTTLAFKFLHGVIVAADSRATAGAYIASQTVKKVIEINPYLLGTMAGGAADCSFWERL 117
            +G   +A K    V +AAD R    A   S    KV E+ P+L   + G A D     + 
Sbjct: 1818 NGAAIIAMKGKDCVAIAADRRFGVQAQTVSMDFDKVFEMGPHLFIGLPGLATDVQTVSQR 1639

Query: 118  LARQCRIYELRNKERISVAAASKLLANMVYQYKGMGLSMGTMICGWDKR--GPGLYYVDS 175
            L  +  +YELR   RI       +++N++Y+ +     +  +I G + +   P +  +D 
Sbjct: 1638 LKFRLNLYELRENRRIKPQTFMSMVSNLLYERRFGPYFVEPVIAGLEPKTFKPYIASMDL 1459

Query: 176  EGNRISGTAFSV-GSGSVYAYGVMDRGYSYDLKVEEAYDLARRAIYQATYRDAYSGGAVN 234
             G  +    F V G+ S   YG+ +  +  DL+ ++ ++   +A+  A  RDA SG    
Sbjct: 1458 IGCPMVTEDFVVSGTCSEQMYGMCESLWEPDLEPDDLFETISQALMNAFDRDAVSGWGGV 1279

Query: 235  LYHVRED 241
            +Y + +D
Sbjct: 1278 VYIIEKD 1258
>20771
          Length = 674

 Score = 54.7 bits (130), Expect = 4e-08,   Method: Compositional matrix adjust.
 Identities = 42/167 (25%), Positives = 81/167 (48%), Gaps = 14/167 (8%)
 Frame = +2

Query: 59  GTTTLAFKFLHGVIVAADSRATAGAYIASQTVKKVIEINPYLLGTMAGGAADCSFWERLL 118
           G+T +  +   GV++A + R T+ + I   +++K++E++ ++   M+G  AD     R L
Sbjct: 179 GSTAIGIQTNEGVVLAVEKRVTS-SLIEPTSIEKIMEVDKHIGCAMSGLIAD----SRTL 343

Query: 119 ARQCRIYELRN-----KERISVAAASKLLANMVYQYKGMGLSMGTM---------ICGWD 164
             + R+ E +N      E +SV + ++ ++N+   +       G M         I G D
Sbjct: 344 IDRARV-EAQNHWFTYNENMSVESVTQAVSNLALAFGDDDPDPGAMSRPFGVALLIAGVD 520

Query: 165 KRGPGLYYVDSEGNRISGTAFSVGSGSVYAYGVMDRGYSYDLKVEEA 211
             GP L+++D  G  I   A ++GSGS  A   +   Y   + +++A
Sbjct: 521 SNGPRLFHMDPSGTFIQYDAKAIGSGSEGAQQALQEQYHKSITLKDA 661
>19360
          Length = 569

 Score = 50.8 bits (120), Expect = 6e-07,   Method: Compositional matrix adjust.
 Identities = 35/118 (29%), Positives = 58/118 (49%), Gaps = 1/118 (0%)
 Frame = +2

Query: 129 NKERISVAAASKLLANMVYQYKGMGLSMGTMICGWDKRGPGLYYVDSEGNRISGTAFSVG 188
           +KE +   AAS+   N  Y Y+   L  G ++ GWD+   G  Y    G  ++  + ++G
Sbjct: 71  SKEPLVWEAASEF-RNFCYNYRD-SLLAGIIVAGWDEERGGQVYSVPLGGMLTRESCTIG 244

Query: 189 -SGSVYAYGVMDRGYSYDLKVEEAYDLARRAIYQATYRDAYSGGAVNLYHVREDGWIR 245
            SGS + YG +   Y   +  EE  +  ++A+  A + D  SGG V +  + +DG  R
Sbjct: 245 GSGSSFIYGFVREHYRPGMPKEECIEFVKKAVQHAIFHDGSSGGVVRIGIIDKDGIER 418
>01337
          Length = 2947

 Score = 46.6 bits (109), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 31/126 (24%), Positives = 63/126 (50%), Gaps = 5/126 (3%)
 Frame = -3

Query: 105  AGGAADCSFWERLLARQCRIYELRNKERISVAAASKL----LANMVYQYKGMGLSMGTMI 160
            AG   D   +   +++  ++Y++RN   +S  AA+      +A+ +   +   +++  ++
Sbjct: 1223 AGEPGDTVQFSEYISKNIQLYKMRNGYELSAKAAANFTRRNVADALRSQRPKFVNI--LM 1050

Query: 161  CGWDKRGPGLYYVDSEGNRISGTAFSV-GSGSVYAYGVMDRGYSYDLKVEEAYDLARRAI 219
             G D  GP L+++D  G  I    F+V G G ++   +MDR Y  D+  +EA  L ++ +
Sbjct: 1049 AGMDDSGPALFFLDYLGALIQ-VPFAVHGYGGMFTLSIMDRYYKKDMNKDEAVTLLQQCV 873

Query: 220  YQATYR 225
             +   R
Sbjct: 872  TEIQKR 855
>28971
          Length = 437

 Score = 29.6 bits (65), Expect = 1.4,   Method: Compositional matrix adjust.
 Identities = 15/41 (36%), Positives = 22/41 (53%)
 Frame = +1

Query: 152 MGLSMGTMICGWDKRGPGLYYVDSEGNRISGTAFSVGSGSV 192
            G+S+  +ICGWD   P LY  D  G   +  A ++G  +V
Sbjct: 37  FGVSL--LICGWDNERPYLYQSDPSGAYFAWKATAMGKNAV 153
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|110625755|ref|NP_081565.1| 5'-nucleotidase domain
containing 2 [Mus musculus]
         (390 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

37567                                                                  97   1e-20
13144                                                                  74   8e-14
20143                                                                  39   0.003
08583                                                                  31   0.76 
26278                                                                  30   1.3  
26019                                                                  28   4.3  
>37567
          Length = 545

 Score = 97.1 bits (240), Expect = 1e-20,   Method: Compositional matrix adjust.
 Identities = 46/103 (44%), Positives = 74/103 (71%)
 Frame = +2

Query: 1   MKIDAFHYVQLGTAYRGLKPVPDDEVIDLYGGTQHIPLYQMSGFYGKGPSIKQFMDIFSL 60
           MKID+FH +QLGT YRG +PV  +EV  LYGGT HI L  M+ +YG GP + Q +D+F++
Sbjct: 242 MKIDSFHNIQLGTVYRGKQPVEPEEVKALYGGT-HISLDYMNTYYGTGP-MHQMIDLFAI 415

Query: 61  PEMALLSCVVDYFLGHGLEFDQVHLYKDVTDAIRDVHVKGLMY 103
           PE++L++ + +YF  H L +D  +++ D+ +A++ +H  GL++
Sbjct: 416 PEISLIAHITEYFNQHSLVYDPEYVFYDIRNAVQGIHNSGLLH 544
>13144
          Length = 457

 Score = 74.3 bits (181), Expect = 8e-14,   Method: Compositional matrix adjust.
 Identities = 51/145 (35%), Positives = 74/145 (51%), Gaps = 13/145 (8%)
 Frame = -2

Query: 103 YQWIEQDMEKYILRGD-ETFAVLSRLVAHGKQLFLITNSPFSFVDKGMRHMVGPDWRQLF 161
           ++ +  D ++Y+L    +    L +L A GK+LFL+T S   F +      +G DWRQ F
Sbjct: 429 FKAMRADPQRYVLPSSVKLLEWLQQLRAMGKKLFLLTGSNIDFANLTATQAMGADWRQQF 250

Query: 162 DVVIVQADKPNFFTDRRKPFRKLDEKG--SLHWDRIT---RLEKGKIYRQGNLFDFLRLT 216
           D ++  A KP FFT +R PF ++DE     L    I+    L  G +Y QGN +  L LT
Sbjct: 249 DFIVTYAKKPGFFTLQR-PFMRVDENAQKELAGSEISLQADLHSGDVYSQGN-WQQLHLT 76

Query: 217 -------EWRGPRVLYFGDHLYSDL 234
                  +    R LYFGD+L  D+
Sbjct: 75  MAKLLNKDASAARALYFGDNLIQDI 1
>20143
          Length = 404

 Score = 39.3 bits (90), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 35/143 (24%), Positives = 62/143 (43%), Gaps = 8/143 (5%)
 Frame = +2

Query: 202 KIYRQGNLFDFLRLTEWRGPRVLYFGDHLYSDLADLMLRHGWRTGAXXXXXXXXXXXXNT 261
           ++Y  G+   F +    +G  VLY GDH++ D+       GWRT                
Sbjct: 2   QVYSGGSCELFTKFINAKGKDVLYVGDHIFGDILKSKKIRGWRT---------FLIVPEL 154

Query: 262 EQYMHSLTWQQALTGLLERMQT-----YQDAESR-QVLATWMKERQELRCITKA--LFNA 313
            + +H  T +  L   L+ +       Y+D +S  +V     + R  +R +T    +   
Sbjct: 155 VRELHVWTDKCQLFAELQNLDIKLGDLYRDLDSSAKVKPDISQLRTCIRDVTHKMDMSYG 334

Query: 314 QFGSIFRTFHNPTYFSRRLVRFS 336
             GS+FR+    T+FS ++VR++
Sbjct: 335 MMGSLFRSGSRQTFFSSQVVRYA 403
>08583
          Length = 1276

 Score = 31.2 bits (69), Expect = 0.76,   Method: Compositional matrix adjust.
 Identities = 22/62 (35%), Positives = 29/62 (46%), Gaps = 1/62 (1%)
 Frame = -2

Query: 319  FRTFHNPTYFSRRLVRFSDLYMAS-LSCLLNYRVDFTFYPRRTPLQHEAPLWMDQLCTGC 377
            FRT HN T  S R +    L+  S LS ++  RV    Y  RT L H   +  D + + C
Sbjct: 1233 FRTEHNDTSSSSRFMSCGPLWAISRLSTMIQVRVH--VYVLRTALGHIGTVHNDTISSSC 1060

Query: 378  MK 379
             K
Sbjct: 1059 FK 1054
>26278
          Length = 407

 Score = 30.4 bits (67), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 19/51 (37%), Positives = 27/51 (52%), Gaps = 3/51 (5%)
 Frame = +3

Query: 334 RFSDLYMASLSCLLNYRVDFTFYPRRTPLQHEA---PLWMDQLCTGCMKTP 381
           R+S L+ A+ +CL      +T+YPRRTP    A   PL +     G + TP
Sbjct: 81  RYSMLWQAAHTCL------YTWYPRRTPAASRALNMPL*LQGSLGGWISTP 215
>26019
          Length = 1561

 Score = 28.5 bits (62), Expect = 4.3,   Method: Compositional matrix adjust.
 Identities = 32/106 (30%), Positives = 48/106 (45%), Gaps = 12/106 (11%)
 Frame = +2

Query: 50  SIKQFMDIFSLPEMALLSCVVDYF--LGHGLEFDQVHLYKDVTDAIRDVHVKG------- 100
           SI +FM +  L +  L+  V+D F   G+G E D    +K+  + I    VKG       
Sbjct: 152 SIDEFMSLPELQQNPLVQRVIDIFDTDGNG-EVD----FKEFIEGISQFSVKGDKESKLR 316

Query: 101 LMYQWIEQDMEKYILRGDETFAVLSRLVAHG---KQLFLITNSPFS 143
             ++  + D + YI  G E F VL  +V +     QL  I + P S
Sbjct: 317 FAFKIYDMDKDGYISNG-ELFQVLKMMVGNNLKDTQLQQIVDKPSS 451
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|12963517|ref|NP_075625.1| deoxythymidylate kinase
isoform 2 [Mus musculus]
         (80 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

25661                                                                  94   1e-20
18316                                                                  53   4e-08
16667                                                                  29   0.57 
23984                                                                  26   3.1  
20144                                                                  25   6.1  
>25661
          Length = 786

 Score = 94.0 bits (232), Expect = 1e-20,   Method: Composition-based stats.
 Identities = 39/76 (51%), Positives = 60/76 (78%)
 Frame = +2

Query: 3   SRRGALIVLEGVDRAGKTTQGLKLVTALCASGHRAELLRFPERSTEIGKLLNSYLEKKTE 62
           ++RG  IV EG D++GK+TQ  +LV  L  +G  A+L++FP+R+T IG ++NSYL++  +
Sbjct: 56  NKRGVFIVFEGCDKSGKSTQCSRLVDRLNENGVPAQLMKFPDRTTAIGTMINSYLQQSCQ 235

Query: 63  LEDHSVHLLFSANRWE 78
           +EDH++HLLF+ANRWE
Sbjct: 236 VEDHAIHLLFAANRWE 283
>18316
          Length = 1913

 Score = 52.8 bits (125), Expect = 4e-08,   Method: Composition-based stats.
 Identities = 19/33 (57%), Positives = 29/33 (87%)
 Frame = -3

Query: 46   STEIGKLLNSYLEKKTELEDHSVHLLFSANRWE 78
            +T IG ++NSYL++  ++EDH++HLLF+ANRWE
Sbjct: 1839 TTAIGTMINSYLQQSCQVEDHAIHLLFAANRWE 1741
>16667
          Length = 1824

 Score = 28.9 bits (63), Expect = 0.57,   Method: Compositional matrix adjust.
 Identities = 23/77 (29%), Positives = 32/77 (41%)
 Frame = +2

Query: 4    RRGALIVLEGVDRAGKTTQGLKLVTALCASGHRAELLRFPERSTEIGKLLNSYLEKKTEL 63
            RRG L V  G   +GKTT        LC  G       F   +  +GK++ +    +T L
Sbjct: 941  RRGELTVFTGPTGSGKTTFMSDYSLDLCMQGVNTLWGSFEINNVRLGKMMLTQF-AQTNL 1117

Query: 64   EDHSVHLLFSANRWEQV 80
                 H    ANR+E +
Sbjct: 1118 SKQLEHFDEWANRFEDL 1168
>23984
          Length = 411

 Score = 26.2 bits (56), Expect = 3.1,   Method: Compositional matrix adjust.
 Identities = 11/34 (32%), Positives = 17/34 (50%)
 Frame = +2

Query: 46  STEIGKLLNSYLEKKTELEDHSVHLLFSANRWEQ 79
           S +I    N  + KKT    HS +  +  N+W+Q
Sbjct: 164 SQQISTKNNKLMRKKTRWSSHSNNSFYKKNKWKQ 265
>20144
          Length = 1326

 Score = 25.4 bits (54), Expect = 6.1,   Method: Composition-based stats.
 Identities = 14/34 (41%), Positives = 18/34 (52%)
 Frame = -3

Query: 17   AGKTTQGLKLVTALCASGHRAELLRFPERSTEIG 50
            A KTTQ LK VT    +G+  E +     + EIG
Sbjct: 1258 AVKTTQRLKTVTVHVGTGNLKESIELARHAGEIG 1157
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|13385060|ref|NP_079881.1| hypothetical protein
LOC66508 [Mus musculus]
         (161 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

22784                                                                  95   1e-20
14207                                                                  44   2e-05
10203                                                                  27   2.8  
05405                                                                  26   6.2  
17857                                                                  26   8.3  
>22784
          Length = 1633

 Score = 94.7 bits (234), Expect = 1e-20,   Method: Compositional matrix adjust.
 Identities = 59/167 (35%), Positives = 96/167 (57%), Gaps = 6/167 (3%)
 Frame = +3

Query: 1   MGCCYSSENEDSDQ---DREERKLLLDPS--STPTKALNGAEPNYHSLPSARTDEQALLS 55
           MGCC+SSE +D D    + +ER  LLDP+  S+  ++L   +   ++  + + D Q++++
Sbjct: 33  MGCCFSSE-DDKDSGFPEPDERTRLLDPTLGSSSAQSLGNQQSQQYTQGNEKGDHQSVMA 209

Query: 56  SILAKTASNIIDVSAADSQGMEQHEYIDRARQYSTRLAVL-SSSLTHWKKLPPLPSLTSQ 114
            IL   A  +IDV++ D+  + QHEY DRARQYSTRL +L  +S         LP+ ++ 
Sbjct: 210 RILEVNAREVIDVASTDTP-IGQHEYHDRARQYSTRLKMLLGNSGKRGVYKMALPNGSTS 386

Query: 115 PHQVLASEPIPFSDLQQVSRIAAYAYSALSQIRVDAKEELVVQFGIP 161
              VLA+ PI  ++   +   A     A+  +R+  +E+LVV FG+P
Sbjct: 387 GLSVLAAPPISSAEAHLICNTAEKMGKAMRDVRIQHREDLVVSFGVP 527
>14207
          Length = 458

 Score = 44.3 bits (103), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 25/76 (32%), Positives = 44/76 (57%), Gaps = 1/76 (1%)
 Frame = +3

Query: 87  QYSTRL-AVLSSSLTHWKKLPPLPSLTSQPHQVLASEPIPFSDLQQVSRIAAYAYSALSQ 145
           QYS+RL ++L++S         LP   + PH VLA+ P+  +++Q +   +     A+ +
Sbjct: 6   QYSSRLKSLLAASDKQGTYRMALPGGLTTPHSVLAAPPVSPAEIQLICNASDRFSKAMKE 185

Query: 146 IRVDAKEELVVQFGIP 161
           + V  +E+LVV FG+P
Sbjct: 186 VHVHHREDLVVSFGVP 233
>10203
          Length = 2103

 Score = 27.3 bits (59), Expect = 2.8,   Method: Compositional matrix adjust.
 Identities = 15/44 (34%), Positives = 22/44 (50%)
 Frame = -2

Query: 63  SNIIDVSAADSQGMEQHEYIDRARQYSTRLAVLSSSLTHWKKLP 106
           +NI+D  AA +Q    H +   A +Y + L   S  +TH   LP
Sbjct: 920 ANIVDPPAAGNQATTNHFFHFDASRYVSWLPSFSVEVTHHSLLP 789
>05405
          Length = 715

 Score = 26.2 bits (56), Expect = 6.2,   Method: Compositional matrix adjust.
 Identities = 11/29 (37%), Positives = 18/29 (62%)
 Frame = +1

Query: 8   ENEDSDQDREERKLLLDPSSTPTKALNGA 36
           +N +SD+DR     ++DP++TP   L  A
Sbjct: 130 QNFNSDKDRTASVKIIDPANTPQTGLKRA 216
>17857
          Length = 1642

 Score = 25.8 bits (55), Expect = 8.3,   Method: Compositional matrix adjust.
 Identities = 15/26 (57%), Positives = 17/26 (65%)
 Frame = -3

Query: 91   RLAVLSSSLTHWKKLPPLPSLTSQPH 116
             +AVL SS +  KK P LPS TS PH
Sbjct: 1235 NVAVLESSFSI*KKFPTLPSFTS-PH 1161
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|21450169|ref|NP_659055.1| phosphoribosyl
pyrophosphate synthetase-associated protein 2 [Mus musculus]
         (369 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

21831                                                                  97   1e-20
23212                                                                  28   8.4  
>21831
          Length = 1374

 Score = 97.1 bits (240), Expect = 1e-20,   Method: Compositional matrix adjust.
 Identities = 42/53 (79%), Positives = 51/53 (96%)
 Frame = -1

Query: 317 EVVVTNTIPHEIQKLQCPKIKTVDISMILSEAIRRIHNGESMSYLFRNIGLDD 369
           +VVVTNT+PHE++K+QC KIKTVDIS +L+EAIRRIH+GESMSYLFRNIG+DD
Sbjct: 807 QVVVTNTVPHEVKKMQCHKIKTVDISSLLAEAIRRIHHGESMSYLFRNIGVDD 649
>23212
          Length = 1398

 Score = 27.7 bits (60), Expect = 8.4,   Method: Compositional matrix adjust.
 Identities = 12/20 (60%), Positives = 13/20 (65%)
 Frame = -3

Query: 220 DLVDGRHSPPMVRSVAAIHP 239
           DL  GRHSP +  S A IHP
Sbjct: 538 DLFRGRHSPSVPHSAAQIHP 479
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6755296|ref|NP_035382.1| RNA binding motif protein,
X-linked [Mus musculus]
         (391 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

16427                                                                  97   1e-20
00302                                                                  74   7e-14
19868                                                                  64   8e-11
33516                                                                  64   2e-10
00817                                                                  62   5e-10
16016                                                                  62   5e-10
32386                                                                  62   6e-10
03000                                                                  60   2e-09
17681                                                                  59   3e-09
12506                                                                  59   4e-09
31618                                                                  57   1e-08
02415                                                                  56   3e-08
11019                                                                  56   3e-08
03059                                                                  55   6e-08
23322                                                                  55   6e-08
02347                                                                  55   6e-08
00029                                                                  53   2e-07
26197                                                                  53   2e-07
03744                                                                  53   2e-07
31310                                                                  52   4e-07
03406                                                                  52   4e-07
04988                                                                  52   4e-07
23720                                                                  52   4e-07
20488                                                                  52   4e-07
01937                                                                  50   2e-06
14637                                                                  50   2e-06
24983                                                                  49   2e-06
14258                                                                  48   5e-06
01278                                                                  48   7e-06
17775                                                                  47   1e-05
30672                                                                  47   1e-05
13822                                                                  47   1e-05
00556                                                                  46   3e-05
10194                                                                  45   6e-05
09968                                                                  44   8e-05
02502                                                                  44   9e-05
03856                                                                  41   8e-04
25691                                                                  40   0.001
28455                                                                  40   0.002
03200                                                                  40   0.002
11687                                                                  40   0.002
05273                                                                  39   0.003
11579                                                                  39   0.004
28652                                                                  39   0.004
23655                                                                  38   0.009
15503                                                                  36   0.028
15371                                                                  36   0.032
00781                                                                  35   0.073
35767                                                                  34   0.090
28372                                                                  33   0.14 
12350                                                                  33   0.16 
33504                                                                  32   0.33 
32733                                                                  32   0.47 
25950                                                                  31   0.74 
23250                                                                  29   2.5  
>16427
          Length = 1313

 Score = 96.7 bits (239), Expect = 1e-20,   Method: Compositional matrix adjust.
 Identities = 43/84 (51%), Positives = 60/84 (71%)
 Frame = +1

Query: 3   EADRPGKLFIGGLNTETNEKALEAVFGKYGRIVEVLLMKDRETNKSRGFAFVTFESPADA 62
           E DRPGKLF+GGL  E +EK LE  F K+GRI E ++++D+    SRGF FVT+E+P DA
Sbjct: 121 EKDRPGKLFVGGLAEEIDEKVLEREFSKFGRITESMVIRDKVRQVSRGFGFVTYENPMDA 300

Query: 63  KDAARDMNGKSLDGKAIKVEQATK 86
           ++A + M+GK + GK + VE A +
Sbjct: 301 EEAVKHMDGKEILGKKLHVEDAVR 372
>00302
          Length = 927

 Score = 74.3 bits (181), Expect = 7e-14,   Method: Compositional matrix adjust.
 Identities = 36/73 (49%), Positives = 49/73 (67%)
 Frame = -1

Query: 10  LFIGGLNTETNEKALEAVFGKYGRIVEVLLMKDRETNKSRGFAFVTFESPADAKDAARDM 69
           L I GL+  T E+ L  VFG+YG I EV ++ DR+T +SRGFAFV F+S  DA +A    
Sbjct: 459 LGIFGLSLYTQERGLREVFGRYGHISEVQVVYDRQTGRSRGFAFVYFKSSEDAHEAKDRC 280

Query: 70  NGKSLDGKAIKVE 82
           NG  +DG+ I+V+
Sbjct: 279 NGIEIDGRKIRVD 241
>19868
          Length = 434

 Score = 64.3 bits (155), Expect = 8e-11,   Method: Compositional matrix adjust.
 Identities = 31/74 (41%), Positives = 47/74 (63%), Gaps = 4/74 (5%)
 Frame = +2

Query: 9  KLFIGGLNTETNEKALEAVFGKYGRIVEVLLMKDRETNKSRGFAFVTFESPADA----KD 64
          K+F+GGL+ +T+ ++L   F K+G I EV++MKD  T +SRGF F+TF  PA        
Sbjct: 2  KMFVGGLSWQTSPESLRDYFNKFGEITEVMVMKDPTTRRSRGFGFITFGDPASVDKVLAQ 181

Query: 65 AARDMNGKSLDGKA 78
          A  +++GK +D K 
Sbjct: 182ATHELDGKKIDPKV 223

 Score = 47.0 bits (110), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 21/52 (40%), Positives = 34/52 (65%)
 Frame = +2

Query: 4   ADRPGKLFIGGLNTETNEKALEAVFGKYGRIVEVLLMKDRETNKSRGFAFVT 55
             R  K+F+GGL+  T  + ++  F ++G I + +LM D++TN+ RGF FVT
Sbjct: 254 VTRTKKIFVGGLSAPTTLEDVKNYFEQFGPIEDAMLMFDKQTNRHRGFGFVT 409
>33516
          Length = 449

 Score = 63.5 bits (153), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 23/56 (41%), Positives = 43/56 (76%)
 Frame = +1

Query: 5   DRPGKLFIGGLNTETNEKALEAVFGKYGRIVEVLLMKDRETNKSRGFAFVTFESPA 60
           + PGK+F+GGL+ +T++ +L+  F ++G I + ++M +++T KSRGF FV+F+ P+
Sbjct: 145 EEPGKIFVGGLSWDTDQDSLQGYFSQFGEITDCIVMMNQQTGKSRGFGFVSFKDPS 312
>00817
          Length = 2606

 Score = 61.6 bits (148), Expect = 5e-10,   Method: Compositional matrix adjust.
 Identities = 29/81 (35%), Positives = 54/81 (66%)
 Frame = -2

Query: 4    ADRPGKLFIGGLNTETNEKALEAVFGKYGRIVEVLLMKDRETNKSRGFAFVTFESPADAK 63
            A+R  K+FIGG++ +T+E +L + F KYG I E +++KD  T +SR F+F+TF +  +  
Sbjct: 2563 AERNRKVFIGGMHPDTDESSLRSYFEKYGDIRECIVVKDPATKRSRCFSFITFGNAENVD 2384

Query: 64   DAARDMNGKSLDGKAIKVEQA 84
            +  +D    ++DG+ ++ ++A
Sbjct: 2383 EVQKD-RPHTIDGRTVETKRA 2324
>16016
          Length = 1364

 Score = 61.6 bits (148), Expect = 5e-10,   Method: Compositional matrix adjust.
 Identities = 29/81 (35%), Positives = 54/81 (66%)
 Frame = -2

Query: 4    ADRPGKLFIGGLNTETNEKALEAVFGKYGRIVEVLLMKDRETNKSRGFAFVTFESPADAK 63
            A+R  K+FIGG++ +T+E +L + F KYG I E +++KD  T +SR F+F+TF +  +  
Sbjct: 1321 AERNRKVFIGGMHPDTDESSLRSYFEKYGDIRECIVVKDPATKRSRCFSFITFGNAENVD 1142

Query: 64   DAARDMNGKSLDGKAIKVEQA 84
            +  +D    ++DG+ ++ ++A
Sbjct: 1141 EVQKD-RPHTIDGRTVETKRA 1082

 Score = 33.9 bits (76), Expect(2) = 8e-04,   Method: Compositional matrix adjust.
 Identities = 15/52 (28%), Positives = 30/52 (57%)
 Frame = -1

Query: 37  VLLMKDRETNKSRGFAFVTFESPADAKDAARDMNGKSLDGKAIKVEQATKPS 88
           + ++KD+ T K RGF FV+F+   D  D         ++G+ ++ ++A++ S
Sbjct: 965 INMIKDKSTGKFRGFCFVSFDD-CDTVDKHAIHKCFKINGRHVEAKKASQQS 813

 Score = 26.2 bits (56), Expect(2) = 8e-04,   Method: Compositional matrix adjust.
 Identities = 12/29 (41%), Positives = 18/29 (62%)
 Frame = -2

Query: 9    KLFIGGLNTETNEKALEAVFGKYGRIVEV 37
            K+F+GGL  +T E+ L   F   G+I E+
Sbjct: 1042 KMFVGGLKDDTTEEMLRKEFT--GKITEL 962
>32386
          Length = 674

 Score = 61.6 bits (148), Expect = 6e-10,   Method: Compositional matrix adjust.
 Identities = 30/81 (37%), Positives = 54/81 (66%)
 Frame = +1

Query: 4   ADRPGKLFIGGLNTETNEKALEAVFGKYGRIVEVLLMKDRETNKSRGFAFVTFESPADAK 63
           A++  KLFIGGL+ ET+E +L + F  +G IV+ ++M+D  + +SRGF F+T++  A++ 
Sbjct: 289 AEQFRKLFIGGLSYETDEDSLRSHFETWGEIVDCIVMRDSNSKRSRGFGFITYKD-AESI 465

Query: 64  DAARDMNGKSLDGKAIKVEQA 84
           D A+      +DG+ +  ++A
Sbjct: 466 DQAQANRPHKIDGREVDTKRA 528
>03000
          Length = 778

 Score = 60.1 bits (144), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 30/81 (37%), Positives = 54/81 (66%)
 Frame = +3

Query: 4   ADRPGKLFIGGLNTETNEKALEAVFGKYGRIVEVLLMKDRETNKSRGFAFVTFESPADAK 63
           A++  KLFIGGL+ ET+E +L + F  +G IV+ ++M+D  + +SRGF F+T++  A++ 
Sbjct: 75  AEQFRKLFIGGLSYETDEDSLRSHFETWGEIVDCIVMRDSNSKRSRGFGFITYK-DAESI 251

Query: 64  DAARDMNGKSLDGKAIKVEQA 84
           D A+      +DG+ +  ++A
Sbjct: 252 DQAQANRPHKIDGREVDTKRA 314

 Score = 55.8 bits (133), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 28/76 (36%), Positives = 46/76 (60%)
 Frame = +3

Query: 9   KLFIGGLNTETNEKALEAVFGKYGRIVEVLLMKDRETNKSRGFAFVTFESPADAKDAARD 68
           K+F+GG+  +T E  +   F ++G I  V L++D+ T K+RGF FVTF    D+ D A  
Sbjct: 363 KMFVGGVKEDTTEDMIRDTFNEFGEITGVDLIQDKGTGKNRGFCFVTF-GDHDSVDKAVL 539

Query: 69  MNGKSLDGKAIKVEQA 84
                L+G+ ++V++A
Sbjct: 540 KKRHDLNGRQVEVKKA 587
>17681
          Length = 964

 Score = 58.9 bits (141), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 25/77 (32%), Positives = 48/77 (62%)
 Frame = +2

Query: 10  LFIGGLNTETNEKALEAVFGKYGRIVEVLLMKDRETNKSRGFAFVTFESPADAKDAARDM 69
           +F+G L+ E   + L   F  +G I    +++D +T KS+G+AFV+F   A+A++A + M
Sbjct: 38  IFVGDLSPEIETETLREAFAPFGEISNCRIVRDPQTMKSKGYAFVSFVKKAEAENAIQAM 217

Query: 70  NGKSLDGKAIKVEQATK 86
           NG+ +  ++I+   +T+
Sbjct: 218 NGQWIGSRSIRTNWSTR 268
>12506
          Length = 1056

 Score = 58.5 bits (140), Expect = 4e-09,   Method: Compositional matrix adjust.
 Identities = 33/77 (42%), Positives = 43/77 (55%)
 Frame = -3

Query: 8    GKLFIGGLNTETNEKALEAVFGKYGRIVEVLLMKDRETNKSRGFAFVTFESPADAKDAAR 67
            G LF  G   E ++K L A F  +G IV++ +  D ET K RGFAF+ FE   DA  A  
Sbjct: 1054 GSLFTAG---EVDDKVLHAAFLPFGDIVDIQIPLDYETEKHRGFAFIEFELAEDAAAAID 884

Query: 68   DMNGKSLDGKAIKVEQA 84
            +MN   L G+ I+V  A
Sbjct: 883  NMNESELFGRTIRVNLA 833
>31618
          Length = 716

 Score = 57.0 bits (136), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 33/73 (45%), Positives = 44/73 (60%), Gaps = 4/73 (5%)
 Frame = +1

Query: 9   KLFIGGLNTETNEKALEAVFGKYGRIVEVLLMKDRETNKSRGFAFVTFES--PADAKDAA 66
           KLF+GGL+ ET EK L   FGKYG I  + +  D +T +SRGFAF+ F +    D   AA
Sbjct: 295 KLFVGGLSWETTEKELRDHFGKYGEIESINVKTDPQTGRSRGFAFIVFTNTEAIDQVSAA 474

Query: 67  RD--MNGKSLDGK 77
            +  +N K +D K
Sbjct: 475 EEHIINSKKVDPK 513

 Score = 32.0 bits (71), Expect(2) = 0.002,   Method: Compositional matrix adjust.
 Identities = 11/28 (39%), Positives = 21/28 (75%)
 Frame = +3

Query: 6   RPGKLFIGGLNTETNEKALEAVFGKYGR 33
           R GK+F+GGL TE +++ ++  F ++G+
Sbjct: 528 RHGKIFVGGLTTEISDEEIKTYFSQFGQ 611

 Score = 26.6 bits (57), Expect(2) = 0.002,   Method: Compositional matrix adjust.
 Identities = 12/34 (35%), Positives = 20/34 (58%)
 Frame = +1

Query: 34  IVEVLLMKDRETNKSRGFAFVTFESPADAKDAAR 67
           IVEV +  D++ +  +GF F+TF+S     D  +
Sbjct: 613 IVEVEMPFDKQKSHRKGFXFITFDSEQVVTDLLK 714
>02415
          Length = 2763

 Score = 55.8 bits (133), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 30/76 (39%), Positives = 43/76 (56%)
 Frame = -1

Query: 9    KLFIGGLNTETNEKALEAVFGKYGRIVEVLLMKDRETNKSRGFAFVTFESPADAKDAARD 68
            K+F+GGL   T + +L   F K+G I E +++ DR+T KSRG+ FVT      A  A +D
Sbjct: 1923 KIFVGGLPYHTTDHSLREYFDKFGDIDEAVVITDRQTGKSRGYGFVTMADRTGADRACKD 1744

Query: 69   MNGKSLDGKAIKVEQA 84
             N   +DG+   V  A
Sbjct: 1743 PN-PIIDGRKANVNLA 1699
>11019
          Length = 552

 Score = 55.8 bits (133), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 26/81 (32%), Positives = 49/81 (60%)
 Frame = -1

Query: 4   ADRPGKLFIGGLNTETNEKALEAVFGKYGRIVEVLLMKDRETNKSRGFAFVTFESPADAK 63
             +  K+F+GGL++ T  + ++  F  YG I E  LM D+ T++ RGFAFVTF++ +   
Sbjct: 246 VTKTKKIFVGGLSSSTTVEDIKNYFKAYGTIEEATLMFDKVTSRHRGFAFVTFDNESTV- 70

Query: 64  DAARDMNGKSLDGKAIKVEQA 84
           D   +++   ++ K ++ ++A
Sbjct: 69  DKVCEIHFHEINSKMVETKKA 7

 Score = 51.6 bits (122), Expect = 6e-07,   Method: Compositional matrix adjust.
 Identities = 27/75 (36%), Positives = 43/75 (57%), Gaps = 1/75 (1%)
 Frame = -1

Query: 12  IGGLNTETNEKALEAVFGKYGRIVEVLLMKDRETNKSRGFAFVTFESPADAKDAARDMNG 71
           IGGL+ +T  + L + F K+G I E ++MKD  + +SRGF FVT++ P++  +     NG
Sbjct: 552 IGGLSWQTTTETLRSYFEKFGEIKESMVMKDPTSKRSRGFGFVTYKDPSNVDNVLA--NG 379

Query: 72  -KSLDGKAIKVEQAT 85
              +D K +     T
Sbjct: 378 PHCIDSKTLNFSNMT 334
>03059
          Length = 1154

 Score = 54.7 bits (130), Expect = 6e-08,   Method: Compositional matrix adjust.
 Identities = 27/75 (36%), Positives = 44/75 (58%), Gaps = 1/75 (1%)
 Frame = -2

Query: 6   RPGKLFIGGLNTETNEKALEAVFGKYGRIVEVLLMKDR-ETNKSRGFAFVTFESPADAKD 64
           +P K+ +G L    N+  ++ +F  YG I  + L  DR   N S+G A+V +E+P DA+ 
Sbjct: 676 KPTKVHVGRLTRNVNKDHIQEIFSLYGTIKFIDLPNDRIHPNTSKGHAYVEYENPEDAEK 497

Query: 65  AARDMNGKSLDGKAI 79
           A + M+G  +DG+ I
Sbjct: 496 AVKYMDGGQIDGQEI 452
>23322
          Length = 471

 Score = 54.7 bits (130), Expect = 6e-08,   Method: Compositional matrix adjust.
 Identities = 28/76 (36%), Positives = 46/76 (60%)
 Frame = -2

Query: 9   KLFIGGLNTETNEKALEAVFGKYGRIVEVLLMKDRETNKSRGFAFVTFESPADAKDAARD 68
           K+F+GG+  +T E  +   F ++G I  V L++D+ T K+RGF FVTF    D+ D A  
Sbjct: 407 KMFVGGVKEDTTEDMIRDTFNEFGEITGVDLIQDKGTGKNRGFCFVTF-GDHDSVDKAVL 231

Query: 69  MNGKSLDGKAIKVEQA 84
                L+G+ ++V++A
Sbjct: 230 KKRHDLNGRQVEVKKA 183
>02347
          Length = 928

 Score = 54.7 bits (130), Expect = 6e-08,   Method: Compositional matrix adjust.
 Identities = 28/78 (35%), Positives = 44/78 (56%)
 Frame = -3

Query: 8   GKLFIGGLNTETNEKALEAVFGKYGRIVEVLLMKDRETNKSRGFAFVTFESPADAKDAAR 67
           GK+++G L  + +EK +E  F  YG +  V + ++       GFAFV FE   DA DA R
Sbjct: 746 GKIYVGDLPPDASEKEVERAFNYYGHLRNVWVARN-----PPGFAFVEFEDTRDADDAVR 582

Query: 68  DMNGKSLDGKAIKVEQAT 85
            ++G  + G  ++VE +T
Sbjct: 581 ALDGTVVCGNRVRVEHST 528
>00029
          Length = 2204

 Score = 53.1 bits (126), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 26/77 (33%), Positives = 44/77 (57%)
 Frame = -3

Query: 9    KLFIGGLNTETNEKALEAVFGKYGRIVEVLLMKDRETNKSRGFAFVTFESPADAKDAARD 68
            K+FIG L  +T+ + L A+F KYG + E  ++K+        F FV      +A DA  +
Sbjct: 2133 KIFIGNLGDDTDPEELRALFEKYGSVAECDVLKN--------FGFVHMVKKGEADDAISN 1978

Query: 69   MNGKSLDGKAIKVEQAT 85
            +NG ++ G+ ++VE +T
Sbjct: 1977 LNGYNIGGQRMRVELST 1927
>26197
          Length = 1365

 Score = 53.1 bits (126), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 29/77 (37%), Positives = 42/77 (54%), Gaps = 4/77 (5%)
 Frame = -2

Query: 3    EADRPGKLFIGGLNTETNEKALEAVFGKYGRIVEVLLMKDRETNKSRGFAFVTFESP--- 59
            E DR  K+F+GGL+ ET+ K L   F K+G +    L  D ++ KSRGF FV F+     
Sbjct: 1307 EDDR--KIFVGGLSWETSSKHLREYFEKFGEVTSCTLKTDLDSGKSRGFGFVVFKEAVTV 1134

Query: 60   -ADAKDAARDMNGKSLD 75
             A  K+    + G+ +D
Sbjct: 1133 DAVVKNKEHKLQGRKID 1083

 Score = 39.7 bits (91), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 20/74 (27%), Positives = 41/74 (55%)
 Frame = -3

Query: 8    GKLFIGGLNTETNEKALEAVFGKYGRIVEVLLMKDRETNKSRGFAFVTFESPADAKDAAR 67
            G+ F+G L+    ++ +E+ F K+G++V V L  D+  ++ R F FV F++    K    
Sbjct: 1051 GRFFVGKLDPGVPQEDVESYFAKFGKVVNVELPYDKVKDQRRAFCFVEFDNDKTVKKVLE 872

Query: 68   DMNGKSLDGKAIKV 81
              + K + G+ +++
Sbjct: 871  QTSHK-IGGQEVRI 833
>03744
          Length = 3486

 Score = 52.8 bits (125), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 26/75 (34%), Positives = 42/75 (56%)
 Frame = -1

Query: 8    GKLFIGGLNTETNEKALEAVFGKYGRIVEVLLMKDRETNKSRGFAFVTFESPADAKDAAR 67
              LFI  L  E  ++ L  +F  +G +V   +  D++TN S+ F FV+++SP  A+ A  
Sbjct: 3216 ANLFIYHLPQEFGDQDLMQMFMPFGNVVSAKVFIDKQTNLSKCFGFVSYDSPLAAQAAIT 3037

Query: 68   DMNGKSLDGKAIKVE 82
             MNG  +  K +KV+
Sbjct: 3036 SMNGFQIGMKRLKVQ 2992
>31310
          Length = 469

 Score = 52.0 bits (123), Expect = 4e-07,   Method: Compositional matrix adjust.
 Identities = 26/73 (35%), Positives = 42/73 (57%)
 Frame = -3

Query: 9   KLFIGGLNTETNEKALEAVFGKYGRIVEVLLMKDRETNKSRGFAFVTFESPADAKDAARD 68
           ++++G +N E  E  ++  F  +G I  V L  D  TNK +GF+F+ ++ P  A+ A   
Sbjct: 320 RIYVGSINFEIREDTIKQAFLPFGPIKSVNLSWDPITNKHKGFSFIEYDVPEAAQLALEQ 141

Query: 69  MNGKSLDGKAIKV 81
           MNG  + G+ IKV
Sbjct: 140 MNGVMIGGRNIKV 102
>03406
          Length = 1292

 Score = 52.0 bits (123), Expect = 4e-07,   Method: Compositional matrix adjust.
 Identities = 29/77 (37%), Positives = 41/77 (53%), Gaps = 4/77 (5%)
 Frame = +3

Query: 3   EADRPGKLFIGGLNTETNEKALEAVFGKYGRIVEVLLMKDRETNKSRGFAFVTFESPAD- 61
           E DR  K+F+GGL+ ET  K L   F K+G +    L  D ++ KSRGF FV F+  A  
Sbjct: 231 EDDR--KIFVGGLSWETXSKHLREYFEKFGEVTSCTLKTDLDSGKSRGFGFVVFKEAATV 404

Query: 62  ---AKDAARDMNGKSLD 75
               K+    + G+ +D
Sbjct: 405 DAVVKNKEHKLQGRKID 455

 Score = 43.5 bits (101), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 23/77 (29%), Positives = 44/77 (57%)
 Frame = +3

Query: 9   KLFIGGLNTETNEKALEAVFGKYGRIVEVLLMKDRETNKSRGFAFVTFESPADAKDAARD 68
           K+F+G L+    ++ +E+ F K+G++V V L  D+  ++ R F FV F++    K     
Sbjct: 489 KIFVGKLDPGVPQEDVESYFAKFGKVVNVELPYDKVKDQRRAFCFVEFDNDKTVKKVLEQ 668

Query: 69  MNGKSLDGKAIKVEQAT 85
            + K + G+ + V++AT
Sbjct: 669 TSHK-IGGQEVDVKKAT 716
>04988
          Length = 705

 Score = 52.0 bits (123), Expect = 4e-07,   Method: Compositional matrix adjust.
 Identities = 27/76 (35%), Positives = 42/76 (55%)
 Frame = -3

Query: 9   KLFIGGLNTETNEKALEAVFGKYGRIVEVLLMKDRETNKSRGFAFVTFESPADAKDAARD 68
           +++IG L  +  EK +E  F  YGR+ +++L          G+ FV FE   DA DA  +
Sbjct: 649 RVYIGRLPYQAREKDIERFFRGYGRVNDIML--------KNGYGFVEFEDFRDADDAVYE 494

Query: 69  MNGKSLDGKAIKVEQA 84
           +NGK L G+ + +E A
Sbjct: 493 LNGKDLCGERVIIEHA 446
>23720
          Length = 739

 Score = 52.0 bits (123), Expect = 4e-07,   Method: Compositional matrix adjust.
 Identities = 27/76 (35%), Positives = 42/76 (55%)
 Frame = -1

Query: 9   KLFIGGLNTETNEKALEAVFGKYGRIVEVLLMKDRETNKSRGFAFVTFESPADAKDAARD 68
           +++IG L  +  EK +E  F  YGR+ +++L          G+ FV FE   DA DA  +
Sbjct: 682 RVYIGRLPYQAREKDIERFFRGYGRVNDIML--------KNGYGFVEFEDFRDADDAVYE 527

Query: 69  MNGKSLDGKAIKVEQA 84
           +NGK L G+ + +E A
Sbjct: 526 LNGKDLCGERVIIEHA 479
>20488
          Length = 3281

 Score = 52.0 bits (123), Expect = 4e-07,   Method: Compositional matrix adjust.
 Identities = 30/91 (32%), Positives = 48/91 (52%), Gaps = 9/91 (9%)
 Frame = +2

Query: 1    MVEADRPGK---------LFIGGLNTETNEKALEAVFGKYGRIVEVLLMKDRETNKSRGF 51
            M +A+  GK         LFI  L  E  ++ L  +F  +G +V   +  D++TN S+ F
Sbjct: 2660 MQQANSAGKHSEGPDGANLFIYHLPQEFGDQDLMQMFMPFGNVVSAKVFIDKQTNLSKCF 2839

Query: 52   AFVTFESPADAKDAARDMNGKSLDGKAIKVE 82
             FV+++SP  A+ A   MNG  +  K +KV+
Sbjct: 2840 GFVSYDSPLAAQAAITSMNGFQIGMKRLKVQ 2932
>01937
          Length = 1320

 Score = 49.7 bits (117), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 23/63 (36%), Positives = 37/63 (58%)
 Frame = -1

Query: 6    RPGKLFIGGLNTETNEKALEAVFGKYGRIVEVLLMKDRETNKSRGFAFVTFESPADAKDA 65
            +  K+F+GGL++ T  +  +  F  YG I E  LM D+ T++ RGFAFVTF++ +     
Sbjct: 1221 KTSKIFVGGLSSSTTVEDXKNYFKAYGTIEEATLMFDKVTSRHRGFAFVTFDNESTVDKV 1042

Query: 66   ARD 68
              +
Sbjct: 1041 CEN 1033
>14637
          Length = 455

 Score = 49.7 bits (117), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 24/66 (36%), Positives = 38/66 (57%)
 Frame = -1

Query: 9   KLFIGGLNTETNEKALEAVFGKYGRIVEVLLMKDRETNKSRGFAFVTFESPADAKDAARD 68
            LFI  L  E  ++ L  +F  +G ++   +  D++TN S+ F FV+++SP  A+DA   
Sbjct: 200 NLFIYHLPQEFGDQDLMQMFMPFGNVISAKVFIDKQTNLSKCFGFVSYDSPMSAQDAISS 21

Query: 69  MNGKSL 74
           MNG  L
Sbjct: 20  MNGFRL 3
>24983
          Length = 433

 Score = 49.3 bits (116), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 28/74 (37%), Positives = 40/74 (54%)
 Frame = -2

Query: 11  FIGGLNTETNEKALEAVFGKYGRIVEVLLMKDRETNKSRGFAFVTFESPADAKDAARDMN 70
            +GGL   T + +L   F K+G I E +++ DR+T KSRG+ FVT      A  A +D N
Sbjct: 306 LLGGLPYHTTDHSLREYFDKFGDIDEAVVITDRQTGKSRGYGFVTMADRTGADRACKDPN 127

Query: 71  GKSLDGKAIKVEQA 84
              +DG+   V  A
Sbjct: 126 -PIIDGRKANVNLA 88
>14258
          Length = 1063

 Score = 48.1 bits (113), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 21/59 (35%), Positives = 36/59 (61%)
 Frame = +2

Query: 24  LEAVFGKYGRIVEVLLMKDRETNKSRGFAFVTFESPADAKDAARDMNGKSLDGKAIKVE 82
           L  +F  +G ++   +  D++TN S+ F FV+++SP  A+DA   MNG  +  K +KV+
Sbjct: 110 LMQMFMPFGNVISAKVFIDKQTNLSKCFGFVSYDSPMSAQDAISSMNGFQIGMKRLKVQ 286
>01278
          Length = 1082

 Score = 47.8 bits (112), Expect = 7e-06,   Method: Compositional matrix adjust.
 Identities = 29/84 (34%), Positives = 44/84 (52%)
 Frame = +2

Query: 5   DRPGKLFIGGLNTETNEKALEAVFGKYGRIVEVLLMKDRETNKSRGFAFVTFESPADAKD 64
           D    + +  L+ +T E  L+ +F  +G I  + L KD+ T +S+GFAF+ F    DA  
Sbjct: 626 DEAATIRVTNLSEDTRESDLQELFRPFGPISRIYLAKDKVTGQSKGFAFINFHRREDASR 805

Query: 65  AARDMNGKSLDGKAIKVEQATKPS 88
           A   ++G   D   + VE A KPS
Sbjct: 806 AIAGVSGFGYDHLILNVEWA-KPS 874
>17775
          Length = 1282

 Score = 47.4 bits (111), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 23/72 (31%), Positives = 42/72 (58%)
 Frame = -2

Query: 10   LFIGGLNTETNEKALEAVFGKYGRIVEVLLMKDRETNKSRGFAFVTFESPADAKDAARDM 69
            L++G L+ +  E  L   F   G ++ + + +D  T +S G+A+V F+ PADA+ A   M
Sbjct: 1188 LYVGDLHPDVTEAMLFEKFSTAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDTM 1009

Query: 70   NGKSLDGKAIKV 81
            N  ++ G+ I++
Sbjct: 1008 NFDTVKGRPIRI 973

 Score = 43.1 bits (100), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 24/78 (30%), Positives = 40/78 (51%)
 Frame = -2

Query: 10  LFIGGLNTETNEKALEAVFGKYGRIVEVLLMKDRETNKSRGFAFVTFESPADAKDAARDM 69
           L++  L+   +++ L   F  +G I    +M   E  +S+GF FV F SP +A  A  +M
Sbjct: 336 LYVKNLDDSIDDERLRKEFSNFGTITSAKIMT--EGGRSKGFGFVCFSSPEEATKAVTEM 163

Query: 70  NGKSLDGKAIKVEQATKP 87
           NG+ +  K + V  A + 
Sbjct: 162 NGRIIVAKPLYVALAQRK 109

 Score = 39.3 bits (90), Expect(2) = 6e-04,   Method: Compositional matrix adjust.
 Identities = 19/43 (44%), Positives = 26/43 (60%)
 Frame = -2

Query: 44  ETNKSRGFAFVTFESPADAKDAARDMNGKSLDGKAIKVEQATK 86
           E  KSRGF FV+FE P  A+ A  ++NG  + G+ I   +A K
Sbjct: 546 EDGKSRGFGFVSFEEPEGAEKAVDEINGTEVSGRIIYCGRAQK 418

 Score = 21.2 bits (43), Expect(2) = 6e-04,   Method: Compositional matrix adjust.
 Identities = 7/18 (38%), Positives = 13/18 (72%)
 Frame = -3

Query: 18  ETNEKALEAVFGKYGRIV 35
           E ++  L  +FGK+G+I+
Sbjct: 623 ELDDDRLRDLFGKHGKII 570
>30672
          Length = 877

 Score = 47.4 bits (111), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 31/89 (34%), Positives = 48/89 (53%), Gaps = 1/89 (1%)
 Frame = +3

Query: 3   EADRPGKLFIGGLNTETNEKALEAVFGKYGRIVEVLLMKDRETNKSRGFAFVTFESPADA 62
           E  +  +L I  L  +  E  + + FGK+G I EV +   ++ ++SRGFAFV F     A
Sbjct: 390 ELGKRCRLIIRNLAFKCKEADIRSHFGKFGTISEVTI-PLKQGDRSRGFAFVQFTEVKAA 566

Query: 63  KDAARDMNGKSLDGKAIKVEQAT-KPSFE 90
           + A  DMNG ++  + + V+ A  K  FE
Sbjct: 567 QKAISDMNGTAIMDRPVAVDWAVAKDRFE 653

 Score = 35.4 bits (80), Expect = 0.039,   Method: Compositional matrix adjust.
 Identities = 25/69 (36%), Positives = 35/69 (50%), Gaps = 4/69 (5%)
 Frame = +3

Query: 10 LFIGGLNTET-NEKALEAVFGKYGRIVEVLLMKDRETNKSRGFAFVTF---ESPADAKDA 65
          LF+  L  ET NEK LEA F + G +    ++  +E  K RGF +V F   E    AKD 
Sbjct: 18 LFVRNLPFETSNEKLLEA-FEQVGPLKTAFVVAGKEPGKCRGFGYVQFSMLEDAIKAKDT 194

Query: 66 ARDMNGKSL 74
              +G+ +
Sbjct: 195VTHCSGRKI 221
>13822
          Length = 963

 Score = 47.0 bits (110), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 27/80 (33%), Positives = 44/80 (55%), Gaps = 1/80 (1%)
 Frame = -1

Query: 7   PGKLFIGGLNTETNEKALEAVFGKYGRIVEV-LLMKDRETNKSRGFAFVTFESPADAKDA 65
           P +L +  +     E  L  + G +G I++V ++  +R    S+GF FVTF   A+A+ A
Sbjct: 345 PKRLHVSNIPFRFREADLRQLLGPFGTILDVEIIFNER---GSKGFGFVTFAHSAEAERA 175

Query: 66  ARDMNGKSLDGKAIKVEQAT 85
              MNG  ++G+ I+V  AT
Sbjct: 174 RDKMNGTVVEGRKIEVNNAT 115
>00556
          Length = 2189

 Score = 45.8 bits (107), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 25/84 (29%), Positives = 44/84 (52%)
 Frame = +3

Query: 2   VEADRPGKLFIGGLNTETNEKALEAVFGKYGRIVEVLLMKDRETNKSRGFAFVTFESPAD 61
           V  D   K+F+GGL +  +E  ++ +   +G +    L++D  T  S+GFAF  +  P+ 
Sbjct: 741 VVQDSDHKIFMGGLPSYLSEDQMKELLLSFGPLKSFNLVRDNATGLSKGFAFCEYLDPSV 920

Query: 62  AKDAARDMNGKSLDGKAIKVEQAT 85
              A   +NG  L  K + V++A+
Sbjct: 921 TDQACAGLNGMQLGDKKLIVQRAS 992
>10194
          Length = 1278

 Score = 44.7 bits (104), Expect = 6e-05,   Method: Compositional matrix adjust.
 Identities = 20/75 (26%), Positives = 44/75 (58%)
 Frame = -3

Query: 10  LFIGGLNTETNEKALEAVFGKYGRIVEVLLMKDRETNKSRGFAFVTFESPADAKDAARDM 69
           +F+G L  +  E+++ + F   G +  + +++DR+TN  +G  ++ F+S AD+   A  +
Sbjct: 400 VFVGNLPFDIEEESVRSHFEDCGDVENIRVVRDRKTNLGKGICYILFKS-ADSVSLALKL 224

Query: 70  NGKSLDGKAIKVEQA 84
           N   L+ + I+V++ 
Sbjct: 223 NNSELEKRQIRVQRC 179
>09968
          Length = 2913

 Score = 44.3 bits (103), Expect = 8e-05,   Method: Compositional matrix adjust.
 Identities = 20/74 (27%), Positives = 40/74 (54%)
 Frame = -1

Query: 10   LFIGGLNTETNEKALEAVFGKYGRIVEVLLMKDRETNKSRGFAFVTFESPADAKDAARDM 69
            L++ GL++ T    L+++FGK+G+++   ++ +  +     F FVT  S  +     + +
Sbjct: 1386 LWVSGLSSSTRATDLKSLFGKHGKVIGAKVVTNTRSPGRLCFGFVTMASADETTKCIQHL 1207

Query: 70   NGKSLDGKAIKVEQ 83
            +   L GK I VE+
Sbjct: 1206 HRTELHGKMISVER 1165
>02502
          Length = 1557

 Score = 44.3 bits (103), Expect = 9e-05,   Method: Compositional matrix adjust.
 Identities = 19/72 (26%), Positives = 38/72 (52%)
 Frame = -3

Query: 10   LFIGGLNTETNEKALEAVFGKYGRIVEVLLMKDRETNKSRGFAFVTFESPADAKDAARDM 69
            ++ GG+N    E+ +   F  +G I+EV + KD      +GFAF+ F +   A +A   +
Sbjct: 1435 VYCGGVNNGLTEELMHNTFKDFGSILEVRIFKD------KGFAFIRFNNKDAATNAICTI 1274

Query: 70   NGKSLDGKAIKV 81
            +G  ++ + ++ 
Sbjct: 1273 HGTVINDQVVRC 1238
>03856
          Length = 1292

 Score = 41.2 bits (95), Expect = 8e-04,   Method: Compositional matrix adjust.
 Identities = 27/80 (33%), Positives = 38/80 (47%)
 Frame = +1

Query: 7    PGKLFIGGLNTETNEKALEAVFGKYGRIVEVLLMKDRETNKSRGFAFVTFESPADAKDAA 66
            P +L+I G  +E  E+ L  +F K   I   + MKD   N   G+AF TF +P   KDA 
Sbjct: 937  PLRLYITGFGSELKEQELYKLFPKAQEITVPVRMKD---NLPIGYAFATFATPEQCKDAH 1107

Query: 67   RDMNGKSLDGKAIKVEQATK 86
                G  +   ++ V  A K
Sbjct: 1108 NKGQGARVQSYSLVVLYAKK 1167
>25691
          Length = 768

 Score = 40.4 bits (93), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 21/52 (40%), Positives = 30/52 (57%)
 Frame = -2

Query: 39  LMKDRETNKSRGFAFVTFESPADAKDAARDMNGKSLDGKAIKVEQATKPSFE 90
           L++D+ T +S G+ FV ++   DA  A   +NG  L  K IKV  A +PS E
Sbjct: 425 LIRDKPTGQSLGYGFVNYKRQEDADKAIHTLNGLRLQNKTIKVSLA-RPSCE 273
>28455
          Length = 573

 Score = 40.0 bits (92), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 23/73 (31%), Positives = 39/73 (53%)
 Frame = -1

Query: 9   KLFIGGLNTETNEKALEAVFGKYGRIVEVLLMKDRETNKSRGFAFVTFESPADAKDAARD 68
           KLF+  L    + +ALE +F ++G++ +V L+  R +  S+G A+V FE+   A  A   
Sbjct: 537 KLFVKNLPFTCSAEALETIFKEHGKVKDVRLVTYR-SGASKGLAYVEFETEEMATQAVMK 361

Query: 69  MNGKSLDGKAIKV 81
            +G  +    I V
Sbjct: 360 TDGLQVGDHMISV 322
>03200
          Length = 657

 Score = 39.7 bits (91), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 23/71 (32%), Positives = 35/71 (49%), Gaps = 1/71 (1%)
 Frame = -1

Query: 21  EKALEAVFGKYGRIVEVLLMKDRETNKSRGFAFVTFESPADAKDAARDMNGKSLDGKAIK 80
           E  L++ F  +G IV + + ++R         FVTFE    A  A  +MNG  +    +K
Sbjct: 453 EDILKSAFSNFGNIVNINIERERNN------GFVTFEKMESADQAIANMNGSMISNVQLK 292

Query: 81  VEQA-TKPSFE 90
           V  A  +PSF+
Sbjct: 291 VMMARRQPSFD 259
>11687
          Length = 676

 Score = 39.7 bits (91), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 21/69 (30%), Positives = 41/69 (59%), Gaps = 1/69 (1%)
 Frame = +3

Query: 9   KLFIGGLNTETNEKALEAVFGKYGRIVEVLLMKDRETNKSRGFAFVTFESPADAKDAARD 68
           KLF+G L+ + +E  +  +F  +G I +  +++D     SRG AF+TF S   A ++ + 
Sbjct: 432 KLFVGMLSKKLSENDVRMLFESFGSIDDCTVLRD-SNGTSRGCAFITFASRQCAMNSIKG 608

Query: 69  M-NGKSLDG 76
           M + ++++G
Sbjct: 609 MHHSQTMEG 635
>05273
          Length = 1009

 Score = 38.9 bits (89), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 17/38 (44%), Positives = 25/38 (65%)
 Frame = -1

Query: 19  TNEKALEAVFGKYGRIVEVLLMKDRETNKSRGFAFVTF 56
           T + +L   F K+G I E +++ DR+T KSRG+ FVT 
Sbjct: 166 TTDHSLREYFDKFGDIDEAVVITDRQTGKSRGYGFVTM 53
>11579
          Length = 1307

 Score = 38.9 bits (89), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 18/37 (48%), Positives = 24/37 (64%)
 Frame = +3

Query: 48 SRGFAFVTFESPADAKDAARDMNGKSLDGKAIKVEQA 84
          SRGFAFV F    DA+DA   M+G  LDG+ ++ + A
Sbjct: 3  SRGFAFVRFYDRRDAEDAMDSMDGALLDGREVRCQMA 113
>28652
          Length = 918

 Score = 38.5 bits (88), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 23/74 (31%), Positives = 40/74 (54%), Gaps = 1/74 (1%)
 Frame = -2

Query: 9   KLFIGGLNTETNEKALEAVFGKYGRIVEVLLMKDRETNKSRGFAFVTFESPADAKDAARD 68
           ++F G +  +  E  L  +F   G I ++ LM D  +N +RG+ FVT+ +   A +A + 
Sbjct: 728 EVFCGKIPRDIFEDELIPLFEDCGTIWDLRLMMDPVSNLNRGYCFVTYTTKEAAAEAVKQ 549

Query: 69  MNGKSL-DGKAIKV 81
            +G  +  GK +KV
Sbjct: 548 HDGYEIRKGKKLKV 507
>23655
          Length = 929

 Score = 37.7 bits (86), Expect = 0.009,   Method: Compositional matrix adjust.
 Identities = 16/44 (36%), Positives = 27/44 (61%)
 Frame = -1

Query: 9   KLFIGGLNTETNEKALEAVFGKYGRIVEVLLMKDRETNKSRGFA 52
           K+F+GG+  +T E  +   F ++G I  V L++D+ T K+R F 
Sbjct: 902 KMFVGGVKEDTTEDMIRDTFNEFGEITGVDLIQDKGTGKNRDFV 771
>15503
          Length = 570

 Score = 35.8 bits (81), Expect = 0.028,   Method: Compositional matrix adjust.
 Identities = 21/72 (29%), Positives = 39/72 (54%)
 Frame = +1

Query: 10  LFIGGLNTETNEKALEAVFGKYGRIVEVLLMKDRETNKSRGFAFVTFESPADAKDAARDM 69
           L++  L  +   + +  +FGKYG I ++ +    ET   +G AFV +E   DAK+A   +
Sbjct: 154 LYVKNLPYKITAEEMYDIFGKYGAIRQIRVGNTPET---KGTAFVVYEDIFDAKNACDHL 324

Query: 70  NGKSLDGKAIKV 81
           +G ++  + + V
Sbjct: 325 SGFNVCNRYLVV 360
>15371
          Length = 383

 Score = 35.8 bits (81), Expect = 0.032,   Method: Composition-based stats.
 Identities = 18/50 (36%), Positives = 30/50 (60%)
 Frame = -2

Query: 10  LFIGGLNTETNEKALEAVFGKYGRIVEVLLMKDRETNKSRGFAFVTFESP 59
           LFI  L  E  ++ L  +F  +G +V   +  D++TN S+ F FV+++SP
Sbjct: 151 LFIYHLPQEFGDQDLMQMFMPFGNVVSAKVFIDKQTNLSKCFGFVSYDSP 2
>00781
          Length = 3170

 Score = 34.7 bits (78), Expect = 0.073,   Method: Compositional matrix adjust.
 Identities = 18/61 (29%), Positives = 35/61 (57%)
 Frame = -1

Query: 10   LFIGGLNTETNEKALEAVFGKYGRIVEVLLMKDRETNKSRGFAFVTFESPADAKDAARDM 69
            +++ G +  T+ + +  +F K G +  V L   + T + +G+AFV F+SP +A  A + +
Sbjct: 2714 VYVEGFHKFTSREWISRMFSKCGTVTYVSLPCFKTTREIKGYAFVEFQSPEEAVKAVQML 2535

Query: 70   N 70
            N
Sbjct: 2534 N 2532
>35767
          Length = 564

 Score = 34.3 bits (77), Expect = 0.090,   Method: Compositional matrix adjust.
 Identities = 29/80 (36%), Positives = 37/80 (46%)
 Frame = +1

Query: 10  LFIGGLNTETNEKALEAVFGKYGRIVEVLLMKDRETNKSRGFAFVTFESPADAKDAARDM 69
           LFI  L  ETNE  L  +F ++    EV L+  R        AFV FE+   A  AA+D 
Sbjct: 268 LFITNLPEETNEMMLSMLFNQFPGFKEVRLVPGR-----HDIAFVEFETDVQA-GAAKD- 426

Query: 70  NGKSLDGKAIKVEQATKPSF 89
              +L G  I    A K +F
Sbjct: 427 ---ALQGFKITPSNAMKITF 477
>28372
          Length = 398

 Score = 33.5 bits (75), Expect = 0.14,   Method: Compositional matrix adjust.
 Identities = 15/33 (45%), Positives = 22/33 (66%)
 Frame = -2

Query: 49  RGFAFVTFESPADAKDAARDMNGKSLDGKAIKV 81
           +GF FVTF   A+A+ A   MNG  ++G+ I+V
Sbjct: 259 QGFGFVTFAHSAEAERARDKMNGTVVEGRKIEV 161
>12350
          Length = 975

 Score = 33.5 bits (75), Expect = 0.16,   Method: Compositional matrix adjust.
 Identities = 17/55 (30%), Positives = 27/55 (49%)
 Frame = -2

Query: 9   KLFIGGLNTETNEKALEAVFGKYGRIVEVLLMKDRETNKSRGFAFVTFESPADAK 63
           K+F+G    +     L   F K+G +V+V + +       R FAFV+F  P  A+
Sbjct: 359 KIFVGRCTDDMTADDLRQFFSKFGEVVDVFIPR-----PFRAFAFVSFADPEVAQ 210
>33504
          Length = 282

 Score = 32.3 bits (72), Expect = 0.33,   Method: Composition-based stats.
 Identities = 14/34 (41%), Positives = 22/34 (64%)
 Frame = +1

Query: 10  LFIGGLNTETNEKALEAVFGKYGRIVEVLLMKDR 43
           +FIGGL  +  E  +  VF +YG IV + L++D+
Sbjct: 175 VFIGGLPYDLTEGDIICVFSQYGEIVNINLVRDK 276
>32733
          Length = 709

 Score = 32.0 bits (71), Expect = 0.47,   Method: Compositional matrix adjust.
 Identities = 17/62 (27%), Positives = 33/62 (53%)
 Frame = +1

Query: 9   KLFIGGLNTETNEKALEAVFGKYGRIVEVLLMKDRETNKSRGFAFVTFESPADAKDAARD 68
           +   G L+ + +E  +  +F  +G I +  +++D     SRG AF+TF S   A ++ + 
Sbjct: 469 RCLWGMLSKKLSENDVRMLFESFGSIDDCTVLRD-SNGTSRGCAFITFASRQCAMNSIKG 645

Query: 69  MN 70
           M+
Sbjct: 646 MH 651
>25950
          Length = 417

 Score = 31.2 bits (69), Expect = 0.74,   Method: Compositional matrix adjust.
 Identities = 20/72 (27%), Positives = 37/72 (51%)
 Frame = -2

Query: 10  LFIGGLNTETNEKALEAVFGKYGRIVEVLLMKDRETNKSRGFAFVTFESPADAKDAARDM 69
           +++G ++   + + LEA F   G I  V ++ ++     +GFA++ F S  +  + A  M
Sbjct: 275 VYVGNVDYGASAEELEAHFHGCGTINRVTILCNKADGHPKGFAYIEFGSK-EYVETALAM 99

Query: 70  NGKSLDGKAIKV 81
           N     G+ IKV
Sbjct: 98  NETLFRGRQIKV 63
>23250
          Length = 1617

 Score = 29.3 bits (64), Expect = 2.5,   Method: Compositional matrix adjust.
 Identities = 16/66 (24%), Positives = 35/66 (53%)
 Frame = -1

Query: 3    EADRPGKLFIGGLNTETNEKALEAVFGKYGRIVEVLLMKDRETNKSRGFAFVTFESPADA 62
            ++DR G +++G +     E  ++  F ++GR+  + L +  +T  S+G+AF+ F +    
Sbjct: 1347 KSDR-GVVYLGHIPAGFYEPQMKRFFSQFGRVTRLRLSRSTKTGGSKGYAFLEF*TRGCG 1171

Query: 63   KDAARD 68
            +   R 
Sbjct: 1170 QGGGRH 1153
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|94397961|ref|XP_983767.1| PREDICTED: similar to FERM
and PDZ domain containing 2 isoform 3 [Mus musculus]
         (1481 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

00990                                                                  99   1e-20
20073                                                                  56   8e-08
17332                                                                  49   1e-05
29705                                                                  48   3e-05
03499                                                                  45   2e-04
27345                                                                  44   7e-04
18811                                                                  42   0.002
01502                                                                  42   0.003
02951                                                                  41   0.003
03831                                                                  40   0.010
08480                                                                  39   0.013
39267                                                                  35   0.24 
38751                                                                  33   0.70 
37239                                                                  33   0.72 
30100                                                                  31   3.3  
00162                                                                  31   4.6  
13951                                                                  30   6.7  
03584                                                                  30   9.2  
>00990
          Length = 3161

 Score = 99.0 bits (245), Expect = 1e-20,   Method: Compositional matrix adjust.
 Identities = 83/297 (27%), Positives = 126/297 (42%), Gaps = 5/297 (1%)
 Frame = +3

Query: 332 VVLLNGRCLEVKCDMESTAGAVFNAVMSFANLEETTYFGLAYVEGEEFFFLDKDTRLCKV 391
           VVLL+G  +  + D  +    +F+ V    +L E  YFGL +V+      L      C +
Sbjct: 270 VVLLDGEHVNFELDRNAEGRELFDKVCQHLDLIEKDYFGLQFVDERISNHLK-----CWL 434

Query: 392 APEGWREQHPKGSVDTFTLFLRIRFFVGHYRLLRHSLTRHQFYLQLRKDILEERLYCNDE 451
           +P+    +  KG    F   L+  F+      LR SLTR    LQ R+DIL  +L     
Sbjct: 435 SPDKRISKQKKGGPWLFDFALK--FYPPDPTQLRESLTRWLVVLQTRRDILSGKLPATYL 608

Query: 452 TLLQLGVLALQAEFGSYPKEQVEGKAYFRIQDYIPARLIERMTAIRVQVEVSEMHRLSSA 511
           T   LG   +QA+ G Y   +  G  Y R   + P + I+ +  I       E+HR    
Sbjct: 609 TQAMLGSYCVQADVGDYDPNEHRGVEYIRDTPFAPNQTIDLLEKI------VELHRQHKG 770

Query: 512 PWGEDAELEFLEIVQQLPEYGVLVHRVSPEKKRPEGKMALGVCTKGIIVYEVRGSRRIAT 571
              ++AE  FLE  ++L  YGV +H            + LGVC  G+ VY      ++  
Sbjct: 771 QTPDEAETNFLENAKKLAMYGVDLHAAQDVNN---VDIMLGVCASGLQVYR----EKLRI 929

Query: 572 SQFPWRETGMISTHRKKLTIT-----SSTTGKKYTFVTNSSKTCKYLLGLCSSQHWF 623
           S+F W +   IS  R++  I      +S     + F   + +  K L  +C   H F
Sbjct: 930 SRFVWPKILKISYKRRQFYIKVRPSDNSAMENSFCFKLATHRLAKRLWKICVEHHAF 1100
>20073
          Length = 582

 Score = 56.2 bits (134), Expect = 8e-08,   Method: Composition-based stats.
 Identities = 36/82 (43%), Positives = 48/82 (58%)
 Frame = +3

Query: 942  LGFSVTGGINTSVPHGGIYVKSIIPGGPAAKEGQILQGDRLLQVDGVSLCGLTHKQAVQC 1001
            LGF+V GG   S P   IY+  IIPGG A +   + +GD+LL V+GVS+ G  H++AV+ 
Sbjct: 6    LGFNVMGGKEQSSP---IYISRIIPGGVADRLNCLKRGDQLLSVNGVSVEGEYHEKAVEL 176

Query: 1002 LKGPGQVARLVLERRGPRAAPQ 1023
            LK      RLV+     R  PQ
Sbjct: 177  LKLAQGSVRLVV-----RYTPQ 227

 Score = 43.5 bits (101), Expect = 6e-04,   Method: Compositional matrix adjust.
 Identities = 32/100 (32%), Positives = 52/100 (52%)
 Frame = +3

Query: 1070 GLGFSFVQMERGNCIHTKSDLVRIKRLFPGQPAEEHGAIAAGDIILAVNGKPIEGLAFQE 1129
            GLGF+ +  +       +S  + I R+ PG  A+    +  GD +L+VNG  +EG   ++
Sbjct: 3    GLGFNVMGGK------EQSSPIYISRIIPGGVADRLNCLKRGDQLLSVNGVSVEGEYHEK 164

Query: 1130 VLHLLRGAPEEVTLLLCRPPPGILPEMEPGWQTPELSGDQ 1169
             + LL+ A   V L++ R  P IL EME  ++  + S  Q
Sbjct: 165  AVELLKLAQGSVRLVV-RYTPQILEEMEARFERQKNSRKQ 281
>17332
          Length = 473

 Score = 48.9 bits (115), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 34/121 (28%), Positives = 59/121 (48%), Gaps = 2/121 (1%)
 Frame = +2

Query: 357 VMSFANLEETTYFGLAYVEGE-EFFFLDKDTRLCKVAPEGWREQHPKGSVDTFTLFLRIR 415
           V    NL E  YFGL +++   +  +LD +  L             KG      L+  ++
Sbjct: 65  VCELLNLHEKDYFGLRFIDASGQTHWLDGNKSL---------SSQLKGCQTPHKLYFGVK 217

Query: 416 FFVGHYRLLRHSLTRHQFYLQLRKDILEERLYCNDETLLQLGVLALQAEFGSY-PKEQVE 474
           F+      LR  +TR+ F+LQ+++DIL+ RL    +   +L   A+Q+E G + P++  +
Sbjct: 218 FYAADPCKLREEITRYLFFLQVKQDILQGRLPVTFDEASELCAYAVQSELGDFDPRQHTD 397

Query: 475 G 475
           G
Sbjct: 398 G 400
>29705
          Length = 674

 Score = 48.1 bits (113), Expect = 3e-05,   Method: Composition-based stats.
 Identities = 31/83 (37%), Positives = 45/83 (54%), Gaps = 1/83 (1%)
 Frame = -1

Query: 948  GGINTSVP-HGGIYVKSIIPGGPAAKEGQILQGDRLLQVDGVSLCGLTHKQAVQCLKGPG 1006
            G  N  +P   GI++  +I GG A ++G+I   DRLL V+  +L  +TH++AV  LK  G
Sbjct: 395  GKGNQHIPGDNGIFITKVIEGGSAEQDGRIAVMDRLLAVNEHNLEDVTHEEAVAALKSTG 216

Query: 1007 QVARLVLERRGPRAAPQCPSADD 1029
             V RL + +  P       S DD
Sbjct: 215  DVVRLTIAK--PTYIADLSSHDD 153

 Score = 32.7 bits (73), Expect = 1.1,   Method: Composition-based stats.
 Identities = 18/56 (32%), Positives = 30/56 (53%)
 Frame = -1

Query: 1093 IKRLFPGQPAEEHGAIAAGDIILAVNGKPIEGLAFQEVLHLLRGAPEEVTLLLCRP 1148
            I ++  G  AE+ G IA  D +LAVN   +E +  +E +  L+   + V L + +P
Sbjct: 353  ITKVIEGGSAEQDGRIAVMDRLLAVNEHNLEDVTHEEAVAALKSTGDVVRLTIAKP 186
>03499
          Length = 1247

 Score = 45.1 bits (105), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 74/277 (26%), Positives = 114/277 (41%), Gaps = 24/277 (8%)
 Frame = -3

Query: 765  VHGFGFVINEGEDAEQTRSGIFISSLIPGGPAERAKKIKPGGKILALNHISLEGFTFSMA 824
            V GFGF I  G D   T   + I +++P GPA    K+K G  I+ +N   + G+T    
Sbjct: 954  VRGFGFTI-VGSDHPDTEF-LQIKNVVPNGPAYLNGKLKTGDVIVFVNTTCVLGYTHQDV 781

Query: 825  VRMIQN-------------------SPDD--MELIISQPKGVCGTIHSEEKNSTASSGMF 863
            V + Q                     PDD   E++ +    +    HS E  S   S + 
Sbjct: 780  VSLFQTISPGETVTLEICRGYPLHFDPDDPNTEIVTTLAVNMPQDGHSSE--SAPFSTLG 607

Query: 864  CTDILSNRCQGRQSPHIHDQDRSVRGTEMAQVQSSPPRQGPHLPLXXXICGAGSCPPSPL 923
             +D+ S+    +  P   D  RS      A V S+       +P        G+ PP  +
Sbjct: 606  GSDLNSSNRSLKSLP---DLARS------ANVHSNMSFSQHSMPGDLKSLSQGNGPPDLV 454

Query: 924  Q-TNTGEIYFVELVKEDGTLGFSVTGGINTSVPHGGIYVKSIIPGGPAAKEGQILQGDRL 982
              T+  EI  + +V+     GF++        P+G   VK I+  G      + LQ + L
Sbjct: 453  TVTSKPEILSINIVRGQMGFGFTIADS-----PYGQ-KVKQILDKG----RCKTLQENDL 304

Query: 983  LQ-VDGVSLCGLTHKQAVQCLKG-PGQVARLVLERRG 1017
            LQ ++ V +  +TH Q VQ LK  P  V   ++ +RG
Sbjct: 303  LQEINRVDVKRMTHAQIVQVLKDCPIGVDTQIIVQRG 193

 Score = 43.1 bits (100), Expect = 9e-04,   Method: Compositional matrix adjust.
 Identities = 26/93 (27%), Positives = 44/93 (47%), Gaps = 2/93 (2%)
 Frame = -3

Query: 928  GEIYFVELVKEDGTLGFSVTGGINTSVPHGGIYVKSIIPGGPAAKEGQILQGDRLLQVDG 987
            GE     LVK     GF++ G  +       + +K+++P GPA   G++  GD ++ V+ 
Sbjct: 987  GEFVKTSLVKSVRGFGFTIVGSDHPDTEF--LQIKNVVPNGPAYLNGKLKTGDVIVFVNT 814

Query: 988  VSLCGLTHKQAVQCLK--GPGQVARLVLERRGP 1018
              + G TH+  V   +   PG+   L + R  P
Sbjct: 813  TCVLGYTHQDVVSLFQTISPGETVTLEICRGYP 715
>27345
          Length = 496

 Score = 43.5 bits (101), Expect = 7e-04,   Method: Composition-based stats.
 Identities = 22/52 (42%), Positives = 34/52 (65%), Gaps = 1/52 (1%)
 Frame = +3

Query: 958  GIYVKSIIPGGPAAKEGQILQGDRLLQVDGVSLCGLTHKQAVQCLKG-PGQV 1008
            GI++K++  GG A K+G+I   D++++VDG SL G+T   A   L+   GQV
Sbjct: 24   GIFIKTLTDGGAAQKDGRIQVNDQIIEVDGKSLVGVTQAYAASVLRNTSGQV 179
>18811
          Length = 478

 Score = 42.0 bits (97), Expect = 0.002,   Method: Composition-based stats.
 Identities = 29/91 (31%), Positives = 45/91 (49%)
 Frame = -2

Query: 501 EVSEMHRLSSAPWGEDAELEFLEIVQQLPEYGVLVHRVSPEKKRPEGKMALGVCTKGIIV 560
           ++ E+HR       ++AE+ +LE  ++L  YGV +H            + LGVC+ G+ V
Sbjct: 339 KIVELHRQHKGQTPDEAEVNYLENAKKLSMYGVDLHAAQDVNNV---DIMLGVCSSGLQV 169

Query: 561 YEVRGSRRIATSQFPWRETGMISTHRKKLTI 591
           Y  R   RI  S+F W +   IS  RK   +
Sbjct: 168 Y--RDKLRI--SRFVWPKIIKISYKRKHFYV 88
>01502
          Length = 1949

 Score = 41.6 bits (96), Expect = 0.003,   Method: Composition-based stats.
 Identities = 25/69 (36%), Positives = 37/69 (53%)
 Frame = +1

Query: 955  PHGGIYVKSIIPGGPAAKEGQILQGDRLLQVDGVSLCGLTHKQAVQCLKGPGQVARLVLE 1014
            P  GIYV  I    PAA+ G  L  D++LQ++G     +THKQAV+ ++    +  LV  
Sbjct: 25   PDKGIYVTFIYENSPAARCGLQLH-DKILQLNGKDFTVVTHKQAVENIRKKPVLKMLVYR 201

Query: 1015 RRGPRAAPQ 1023
            +  P+   Q
Sbjct: 202  KGVPQLQKQ 228
>02951
          Length = 1076

 Score = 41.2 bits (95), Expect = 0.003,   Method: Composition-based stats.
 Identities = 25/69 (36%), Positives = 37/69 (53%)
 Frame = +2

Query: 955  PHGGIYVKSIIPGGPAAKEGQILQGDRLLQVDGVSLCGLTHKQAVQCLKGPGQVARLVLE 1014
            P  GIYV  I    PAA+ G  L  D++LQ++G     +THKQAV+ ++    +  LV  
Sbjct: 11   PDKGIYVTFIYENSPAARCGLQLH-DKILQLNGKDFTVVTHKQAVENIRKKPVLKMLVYR 187

Query: 1015 RRGPRAAPQ 1023
            +  P+   Q
Sbjct: 188  KGVPQLQKQ 214
>03831
          Length = 1143

 Score = 39.7 bits (91), Expect = 0.010,   Method: Compositional matrix adjust.
 Identities = 49/217 (22%), Positives = 89/217 (41%), Gaps = 28/217 (12%)
 Frame = +3

Query: 958  GIYVKSIIPGGPAAKEGQILQGDRLLQVDGVSLCGLTHKQAVQCLKGPGQVARLVLERRG 1017
            G ++  +  G PA   G +  GDR+++V+G ++    H+Q V  +K  G   RL++    
Sbjct: 207  GQFIGKVDEGSPAEAAG-LKAGDRIVEVNGTNIGNENHQQVVGRIKAGGDETRLLVV--- 374

Query: 1018 PRAAPQCPSADDRM--GDVHMAVSLVTARPGRP---------ASSVSVTDGPKFEVKLKK 1066
             +   Q    + R+  GD+     +  AR  +          A+ V  T+G + E +   
Sbjct: 375  DQETDQHYKEEKRVVRGDLPETRFMTAAREQKDNXENQEAEIAAVVEATNGTEPEPQSLP 554

Query: 1067 NSRGL---------------GFSFVQMERGNCIHTKSDL--VRIKRLFPGQPAEEHGAIA 1109
            +   L               G+ F        +H + D     I  + P  PAE  G + 
Sbjct: 555  DESSLYAPRLCHLCKWADFDGYGF-------NLHAEKDKPGQYIGSVDPNSPAET-GGLK 710

Query: 1110 AGDIILAVNGKPIEGLAFQEVLHLLRGAPEEVTLLLC 1146
             GD I+ VNG+ IE      V+  ++   ++ ++L+ 
Sbjct: 711  EGDRIIEVNGENIETTNHTAVIQNIKSRGDKTSMLVV 821
>08480
          Length = 698

 Score = 39.3 bits (90), Expect = 0.013,   Method: Compositional matrix adjust.
 Identities = 17/45 (37%), Positives = 26/45 (57%)
 Frame = -1

Query: 968  GPAAKEGQILQGDRLLQVDGVSLCGLTHKQAVQCLKGPGQVARLV 1012
            GPA   G + +GD++L V+ V +   TH+QA Q LK  G    ++
Sbjct: 698  GPADLSGDLRRGDKILSVNDVDVERATHEQAAQALKRAGDTVEII 564

 Score = 32.7 bits (73), Expect = 0.98,   Method: Compositional matrix adjust.
 Identities = 14/45 (31%), Positives = 28/45 (62%)
 Frame = -1

Query: 794 GPAERAKKIKPGGKILALNHISLEGFTFSMAVRMIQNSPDDMELI 838
           GPA+ +  ++ G KIL++N + +E  T   A + ++ + D +E+I
Sbjct: 698 GPADLSGDLRRGDKILSVNDVDVERATHEQAAQALKRAGDTVEII 564
>39267
          Length = 456

 Score = 35.0 bits (79), Expect = 0.24,   Method: Compositional matrix adjust.
 Identities = 19/61 (31%), Positives = 34/61 (55%)
 Frame = +1

Query: 942  LGFSVTGGINTSVPHGGIYVKSIIPGGPAAKEGQILQGDRLLQVDGVSLCGLTHKQAVQC 1001
            LGF+++G +       GIYV  +   GPA++ G+I  GDR+  V  ++   + ++ A+  
Sbjct: 118  LGFNISGNMRD-----GIYVSQLHNRGPASESGKIHVGDRIQSVT-IAYDNIVYEDALTI 279

Query: 1002 L 1002
            L
Sbjct: 280  L 282
>38751
          Length = 329

 Score = 33.5 bits (75), Expect = 0.70,   Method: Composition-based stats.
 Identities = 24/84 (28%), Positives = 35/84 (41%)
 Frame = +3

Query: 949  GINTSVPHGGIYVKSIIPGGPAAKEGQILQGDRLLQVDGVSLCGLTHKQAVQCLKGPGQV 1008
            GI     +G   V  +I  G  A++  +  GDR+L V+G     LTH +AV  ++    V
Sbjct: 6    GIKGGKEYGTPIVVYVIEEGCQAEQQGLNIGDRILDVNGTDFTHLTHAEAVTIMRNAWNV 185

Query: 1009 ARLVLERRGPRAAPQCPSADDRMG 1032
               V           CP +D   G
Sbjct: 186  IMTV---------QPCPESDSGQG 230
>37239
          Length = 453

 Score = 33.5 bits (75), Expect = 0.72,   Method: Composition-based stats.
 Identities = 14/25 (56%), Positives = 18/25 (72%)
 Frame = -3

Query: 958 GIYVKSIIPGGPAAKEGQILQGDRL 982
           GIY++ I  GG AAK+GQ+  GD L
Sbjct: 76  GIYIRHITIGGAAAKDGQLAVGDEL 2
>30100
          Length = 526

 Score = 31.2 bits (69), Expect = 3.3,   Method: Composition-based stats.
 Identities = 12/26 (46%), Positives = 16/26 (61%)
 Frame = -2

Query: 585 HRKKLTITSSTTGKKYTFVTNSSKTC 610
           H++K+T      G KYTFV+N   TC
Sbjct: 321 HKEKIT*KQINIGTKYTFVSNQQSTC 244
>00162
          Length = 2322

 Score = 30.8 bits (68), Expect = 4.6,   Method: Compositional matrix adjust.
 Identities = 23/61 (37%), Positives = 28/61 (45%), Gaps = 6/61 (9%)
 Frame = -1

Query: 238  TAHSRNSFVNSTFAGAGPC-----DCEE-SPWYGSEPMLLAEAESSQPATSSPRNFLQRK 291
            TA S  S       G GPC      CEE +  +   P L+     SQP  +SPR  L+RK
Sbjct: 2214 TALSSTSKTRVLPGGXGPCRELPYPCEEGTVIFRFPPTLMPIKPLSQPLMTSPRPSLKRK 2035

Query: 292  G 292
            G
Sbjct: 2034 G 2032
>13951
          Length = 720

 Score = 30.0 bits (66), Expect = 6.7,   Method: Composition-based stats.
 Identities = 15/44 (34%), Positives = 24/44 (54%)
 Frame = -2

Query: 332 VVLLNGRCLEVKCDMESTAGAVFNAVMSFANLEETTYFGLAYVE 375
           VVLL+G  +  + D  +    +F+ V    +L E  YFGL +V+
Sbjct: 380 VVLLDGEHVNFELDRNAEGRELFDKVCQHLDLIEKDYFGLQFVD 249
>03584
          Length = 1178

 Score = 29.6 bits (65), Expect = 9.2,   Method: Composition-based stats.
 Identities = 14/45 (31%), Positives = 21/45 (46%), Gaps = 1/45 (2%)
 Frame = -3

Query: 1232 MHPMESHPHVCKLHPEPETPALATSLEK-DMRQNCYSVCDIRRLG 1275
            +HP+ +H H+C       TP     L K D  +N Y  C +  +G
Sbjct: 702  LHPLNTHTHIC-------TPTKGWQLHKVDXXENFYHACXVTGMG 589
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|21312570|ref|NP_081676.1| lectin, mannose-binding, 1
[Mus musculus]
         (517 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

27616                                                                  97   2e-20
31479                                                                  59   5e-09
25759                                                                  50   3e-06
28871                                                                  44   5e-06
19172                                                                  30   3.2  
>27616
          Length = 686

 Score = 96.7 bits (239), Expect = 2e-20,   Method: Compositional matrix adjust.
 Identities = 54/142 (38%), Positives = 78/142 (54%), Gaps = 3/142 (2%)
 Frame = +1

Query: 145 VFGSADTWNGVGIFFDSFDNDGKKNN---PAIVVIGNNGQINYDHQNDGATQALASCQRD 201
           VFG+ D + G+GI  D++ N    +N   P I  + NNG + YDH  DG    +A C+  
Sbjct: 7   VFGNRDGFTGLGISLDTYSNHNGPHNHQHPYISAMINNGTLQYDHDTDGTHTQIAGCEAQ 186

Query: 202 FRNKPYPVRAKITYYQKTLTVMINNGFTPDKNDYEFCAKVENMVIPTQGHFGISAATGGL 261
           FRNK Y     + Y  +TL V ++     +KN +  C KV  + +P   +FG SAATG L
Sbjct: 187 FRNKDYDTHMAVRYEGETLKVSVD---VDNKNGWRECFKVHGVKLPVGYYFGASAATGDL 357

Query: 262 ADDHDVLSFLTFQLTEPGKEPP 283
           AD+HD++S   ++L E  K  P
Sbjct: 358 ADNHDIISIKFYEL-ETDKNVP 420
>31479
          Length = 371

 Score = 58.9 bits (141), Expect = 5e-09,   Method: Composition-based stats.
 Identities = 28/81 (34%), Positives = 45/81 (55%), Gaps = 2/81 (2%)
 Frame = +3

Query: 92  PSLKSQRGSVWTKAKAAFENWEVEVTFRVTGRGRIGA--DGLAIWYTENQGLDGPVFGSA 149
           P+L S++G++W   K    NWEV V F+V G  +  +    L   YT+ +   GPVFG+ 
Sbjct: 111 PNLPSKQGAIWNNVKCMVSNWEVHVQFKVHGGSKKTSLETALHFGYTKERTQMGPVFGNK 290

Query: 150 DTWNGVGIFFDSFDNDGKKNN 170
           + + G+ IF D++ N    +N
Sbjct: 291 NGFTGLAIFLDTYSNHNGPHN 353
>25759
          Length = 772

 Score = 49.7 bits (117), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 25/70 (35%), Positives = 39/70 (55%)
 Frame = -1

Query: 198 CQRDFRNKPYPVRAKITYYQKTLTVMINNGFTPDKNDYEFCAKVENMVIPTQGHFGISAA 257
           C+  FRN  Y     I Y    L+V  +     ++N+++ C  V N+ +PT  +FG+SA 
Sbjct: 772 CEVRFRNVDYETFISIRYENDVLSVSTD---LENRNEWKNCFVVTNVELPTGYYFGLSAT 602

Query: 258 TGGLADDHDV 267
           TG L+D HD+
Sbjct: 601 TGDLSDAHDI 572
>28871
          Length = 516

 Score = 44.3 bits (103), Expect(2) = 5e-06,   Method: Compositional matrix adjust.
 Identities = 20/51 (39%), Positives = 32/51 (62%)
 Frame = +1

Query: 231 DKNDYEFCAKVENMVIPTQGHFGISAATGGLADDHDVLSFLTFQLTEPGKE 281
           +KN +E C  V+ + +P   +FG SAATG L D+HD++S   ++L    K+
Sbjct: 136 NKNQWEECFIVKGIKLPVGYYFGASAATGELTDNHDIISIKFYELESQNKD 288

 Score = 24.3 bits (51), Expect(2) = 5e-06,   Method: Composition-based stats.
 Identities = 9/24 (37%), Positives = 12/24 (50%)
 Frame = +2

Query: 192 TQALASCQRDFRNKPYPVRAKITY 215
           T  +A C+  FRNK Y     + Y
Sbjct: 29  TTQIAGCEAQFRNKDYDTLMAVRY 100
>19172
          Length = 484

 Score = 29.6 bits (65), Expect = 3.2,   Method: Composition-based stats.
 Identities = 18/52 (34%), Positives = 25/52 (48%)
 Frame = -1

Query: 352 EIKQLNRQLDMILDEQRRYVSSLTEEISRRGAGTPGQPGQVSQQELDTVVKS 403
           +I   N    +I  E ++ V  +T  ISR+G       G  SQQE D V+ S
Sbjct: 355 QISGENETKTIIFVETKKRVDEITRNISRQGWRACAIHGDKSQQERDFVLSS 200
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|26006861|ref|NP_742146.1| pyridoxal (pyridoxine,
vitamin B6) kinase [Mus musculus]
         (312 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

07186                                                                  96   2e-20
14596                                                                  28   4.2  
00983                                                                  28   4.3  
22725                                                                  28   6.4  
>07186
          Length = 727

 Score = 95.5 bits (236), Expect = 2e-20,   Method: Compositional matrix adjust.
 Identities = 46/79 (58%), Positives = 62/79 (78%)
 Frame = +3

Query: 231 VGTGDLFAAMLLAWTHKHPDNLKVACEKTVSAMQHVLQRTIRCAKAEAGEGQKPSPAQLE 290
           VGTGDLFAA LL W H+  D LKVA EKT++ +Q V+++T+  A+ +AGEG+KP+PAQ E
Sbjct: 3   VGTGDLFAASLLGWMHRDRD-LKVALEKTIATVQGVIKKTLAYAQKQAGEGKKPTPAQSE 179

Query: 291 LRMVQSKRDIEDPEIVVQA 309
           LR++QSK+ IE P I +QA
Sbjct: 180 LRLIQSKKIIESPHIDIQA 236
>14596
          Length = 405

 Score = 28.1 bits (61), Expect = 4.2,   Method: Compositional matrix adjust.
 Identities = 21/64 (32%), Positives = 27/64 (42%), Gaps = 11/64 (17%)
 Frame = +2

Query: 166 EEAFEVMDMLHCMGPDTVVITSSDLPSS-----------QGSDYLIALGSQRMRKPDGST 214
             AF +   LHC  P T+V+     PS+           +GSD     G  R  KPD S 
Sbjct: 203 PSAFCLSYSLHC*TP-TIVVLQKVFPSAFSLSYNALLGNKGSDLTHNQGGHRKTKPDSSP 379

Query: 215 VTQR 218
            T+R
Sbjct: 380 PTRR 391
>00983
          Length = 819

 Score = 28.1 bits (61), Expect = 4.3,   Method: Compositional matrix adjust.
 Identities = 10/24 (41%), Positives = 17/24 (70%)
 Frame = -2

Query: 46  HTGYAHWKGQVLKSQELHELYEGL 69
           + G+AH   Q++K Q LH +Y+G+
Sbjct: 809 YRGFAHGISQIIKEQGLHGVYQGV 738
>22725
          Length = 391

 Score = 27.7 bits (60), Expect = 6.4,   Method: Compositional matrix adjust.
 Identities = 12/37 (32%), Positives = 25/37 (67%)
 Frame = +2

Query: 72  NDVNKYDYVLTGYTRDKSFLAMVVDIVRELKQQNSRL 108
           +D N Y ++ T YT+ +S + + +DI+ + K++NS +
Sbjct: 101 DDTNVYSFITTVYTKGQSCIHISIDIILK-KEENSCI 208
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31543250|ref|NP_032626.2| major intrinsic protein of
eye lens fiber [Mus musculus]
         (263 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

17581                                                                  95   2e-20
20627                                                                  49   2e-06
>17581
          Length = 466

 Score = 95.1 bits (235), Expect = 2e-20,   Method: Compositional matrix adjust.
 Identities = 49/136 (36%), Positives = 70/136 (51%), Gaps = 2/136 (1%)
 Frame = +2

Query: 105 YSVTPPAVRGNLALNTLH--AGVSVGQATTVEIFLTLQFVLCIFATYDERRNGRMGSVAL 162
           Y +TP   RG L    +    GV+  Q   VE+ +T  FV+  FA+ D  R+   GS  L
Sbjct: 56  YGLTPEGRRGTLGATVISDAGGVTAAQGFGVEMLITFIFVMAFFASRDSNRSDLAGSYPL 235

Query: 163 AVGFSLTLGHLFGMYYTGAGMNPARSFAPAILTRNFSNHWVYWVGPIIXXXXXXXXYDFL 222
            VG ++ +  LF + YT AGMN ARSF PA++   + +HWVYWVGP+         YD++
Sbjct: 236 TVGLAVVVCQLFAIDYTAAGMNCARSFGPAVIMGIWDDHWVYWVGPLSGGITAGLLYDYI 415

Query: 223 LFPRLKSVSERLSILK 238
                     R  +L+
Sbjct: 416 FSAGATVTKARKCLLR 463
>20627
          Length = 566

 Score = 49.3 bits (116), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 24/54 (44%), Positives = 35/54 (64%), Gaps = 5/54 (9%)
 Frame = -2

Query: 162 LAVGFSLTLGHLFGMYYTGAGMNPARSFAPAI-----LTRNFSNHWVYWVGPII 210
           LA+G ++    L G+  TGA MNPARSF PA+      +  ++ H+VYWVGP++
Sbjct: 448 LAIGLAVAADILAGVTITGASMNPARSFGPAVTISFATSDYWTYHYVYWVGPLV 287
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|7305075|ref|NP_038744.1| ras-GTPase-activating
protein SH3-domain  binding protein [Mus musculus]
         (465 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

26656                                                                  96   2e-20
32386                                                                  49   4e-06
03000                                                                  48   7e-06
26197                                                                  47   1e-05
03406                                                                  47   2e-05
03744                                                                  42   4e-04
20488                                                                  42   4e-04
17775                                                                  42   5e-04
19868                                                                  39   0.003
08958                                                                  37   0.014
13457                                                                  34   0.015
15503                                                                  36   0.030
14637                                                                  36   0.037
02415                                                                  36   0.037
10194                                                                  36   0.042
04988                                                                  35   0.047
11687                                                                  35   0.049
23720                                                                  35   0.055
03200                                                                  35   0.084
15371                                                                  35   0.090
16427                                                                  33   0.21 
21096                                                                  33   0.35 
24983                                                                  32   0.53 
11108                                                                  31   1.3  
30672                                                                  30   1.9  
00556                                                                  30   2.0  
39789                                                                  29   3.5  
36115                                                                  29   3.9  
33504                                                                  28   7.0  
>26656
          Length = 458

 Score = 96.3 bits (238), Expect = 2e-20,   Method: Compositional matrix adjust.
 Identities = 41/76 (53%), Positives = 55/76 (72%)
 Frame = -2

Query: 11  VGREFVRQYYTLLNQAPDMLHRFYGKNSSYAHGGLDSNGKPADAVYGQKEIHRKVMSQNF 70
           VGREFVRQYYTL+++AP  LHRFY + S + HGG++  G+    V GQ  IH++++  NF
Sbjct: 232 VGREFVRQYYTLMHEAPQHLHRFYSQKSCFVHGGVEKPGEENAPVCGQHAIHQRILELNF 53

Query: 71  TNCHTKIRHVDAHATL 86
            +CH KIR VD+H TL
Sbjct: 52  HDCHAKIRQVDSHPTL 5
>32386
          Length = 674

 Score = 48.9 bits (115), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 20/62 (32%), Positives = 38/62 (61%), Gaps = 3/62 (4%)
 Frame = +1

Query: 339 QLFIGNLPHEVDKSELKDFFQNFGNVVE---LRINSGGKLPNFGFVVFDDSEPVQKVLSN 395
           +LFIG L +E D+  L+  F+ +G +V+   +R ++  +   FGF+ + D+E + +  +N
Sbjct: 304 KLFIGGLSYETDEDSLRSHFETWGEIVDCIVMRDSNSKRSRGFGFITYKDAESIDQAQAN 483

Query: 396 RP 397
           RP
Sbjct: 484 RP 489
>03000
          Length = 778

 Score = 48.1 bits (113), Expect = 7e-06,   Method: Compositional matrix adjust.
 Identities = 20/62 (32%), Positives = 38/62 (61%), Gaps = 3/62 (4%)
 Frame = +3

Query: 339 QLFIGNLPHEVDKSELKDFFQNFGNVVE---LRINSGGKLPNFGFVVFDDSEPVQKVLSN 395
           +LFIG L +E D+  L+  F+ +G +V+   +R ++  +   FGF+ + D+E + +  +N
Sbjct: 90  KLFIGGLSYETDEDSLRSHFETWGEIVDCIVMRDSNSKRSRGFGFITYKDAESIDQAQAN 269

Query: 396 RP 397
           RP
Sbjct: 270 RP 275
>26197
          Length = 1365

 Score = 47.0 bits (110), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 22/71 (30%), Positives = 36/71 (50%), Gaps = 3/71 (4%)
 Frame = -2

Query: 335  PDSHQLFIGNLPHEVDKSELKDFFQNFGNVVELRINS---GGKLPNFGFVVFDDSEPVQK 391
             D  ++F+G L  E     L+++F+ FG V    + +    GK   FGFVVF ++  V  
Sbjct: 1307 EDDRKIFVGGLSWETSSKHLREYFEKFGEVTSCTLKTDLDSGKSRGFGFVVFKEAVTVDA 1128

Query: 392  VLSNRPIMFRG 402
            V+ N+    +G
Sbjct: 1127 VVKNKEHKLQG 1095

 Score = 30.0 bits (66), Expect = 1.9,   Method: Compositional matrix adjust.
 Identities = 18/60 (30%), Positives = 31/60 (51%), Gaps = 3/60 (5%)
 Frame = -3

Query: 339  QLFIGNLPHEVDKSELKDFFQNFGNVVELRI---NSGGKLPNFGFVVFDDSEPVQKVLSN 395
            + F+G L   V + +++ +F  FG VV + +       +   F FV FD+ + V+KVL  
Sbjct: 1048 RFFVGKLDPGVPQEDVESYFAKFGKVVNVELPYDKVKDQRRAFCFVEFDNDKTVKKVLEQ 869
>03406
          Length = 1292

 Score = 46.6 bits (109), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 25/82 (30%), Positives = 40/82 (48%), Gaps = 3/82 (3%)
 Frame = +3

Query: 324 GDVEPRRMVRHPDSHQLFIGNLPHEVDKSELKDFFQNFGNVVELRINS---GGKLPNFGF 380
           GD E      + D  ++F+G L  E     L+++F+ FG V    + +    GK   FGF
Sbjct: 210 GDAEEE----NEDDRKIFVGGLSWETXSKHLREYFEKFGEVTSCTLKTDLDSGKSRGFGF 377

Query: 381 VVFDDSEPVQKVLSNRPIMFRG 402
           VVF ++  V  V+ N+    +G
Sbjct: 378 VVFKEAATVDAVVKNKEHKLQG 443

 Score = 33.1 bits (74), Expect = 0.25,   Method: Compositional matrix adjust.
 Identities = 22/75 (29%), Positives = 39/75 (52%), Gaps = 3/75 (4%)
 Frame = +3

Query: 322 EPGDVEPRRMVRHPDSHQLFIGNLPHEVDKSELKDFFQNFGNVVELRI---NSGGKLPNF 378
           +P    PR+ +R     ++F+G L   V + +++ +F  FG VV + +       +   F
Sbjct: 453 DPKPANPRKGMR-----KIFVGKLDPGVPQEDVESYFAKFGKVVNVELPYDKVKDQRRAF 617

Query: 379 GFVVFDDSEPVQKVL 393
            FV FD+ + V+KVL
Sbjct: 618 CFVEFDNDKTVKKVL 662
>03744
          Length = 3486

 Score = 42.4 bits (98), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 31/101 (30%), Positives = 46/101 (45%), Gaps = 3/101 (2%)
 Frame = -1

Query: 317  IREAGEPGDVEPRRMVRHPDSHQLFIGNLPHEVDKSELKDFFQNFGNVVELR--INSGGK 374
            +++A   G       V  PD   LFI +LP E    +L   F  FGNVV  +  I+    
Sbjct: 3279 MQQANSAGKHSEGPRVPGPDGANLFIYHLPQEFGDQDLMQMFMPFGNVVSAKVFIDKQTN 3100

Query: 375  LPN-FGFVVFDDSEPVQKVLSNRPIMFRGAVRLNVEEKKTR 414
            L   FGFV +D     Q  +++      G  RL V+ K+++
Sbjct: 3099 LSKCFGFVSYDSPLAAQAAITSMNGFQIGMKRLKVQLKRSK 2977
>20488
          Length = 3281

 Score = 42.4 bits (98), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 28/83 (33%), Positives = 40/83 (48%), Gaps = 3/83 (3%)
 Frame = +2

Query: 335  PDSHQLFIGNLPHEVDKSELKDFFQNFGNVVELR--INSGGKLPN-FGFVVFDDSEPVQK 391
            PD   LFI +LP E    +L   F  FGNVV  +  I+    L   FGFV +D     Q 
Sbjct: 2699 PDGANLFIYHLPQEFGDQDLMQMFMPFGNVVSAKVFIDKQTNLSKCFGFVSYDSPLAAQA 2878

Query: 392  VLSNRPIMFRGAVRLNVEEKKTR 414
             +++      G  RL V+ K+++
Sbjct: 2879 AITSMNGFQIGMKRLKVQLKRSK 2947
>17775
          Length = 1282

 Score = 42.0 bits (97), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 19/56 (33%), Positives = 28/56 (50%), Gaps = 1/56 (1%)
 Frame = -2

Query: 340 LFIGNLPHEVDKSELKDFFQNFGNVVELRI-NSGGKLPNFGFVVFDDSEPVQKVLS 394
           L++ NL   +D   L+  F NFG +   +I   GG+   FGFV F   E   K ++
Sbjct: 336 LYVKNLDDSIDDERLRKEFSNFGTITSAKIMTEGGRSKGFGFVCFSSPEEATKAVT 169
>19868
          Length = 434

 Score = 39.3 bits (90), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 18/60 (30%), Positives = 31/60 (51%), Gaps = 3/60 (5%)
 Frame = +2

Query: 339 QLFIGNLPHEVDKSELKDFFQNFGNVVELRIN---SGGKLPNFGFVVFDDSEPVQKVLSN 395
           ++F+G L  +     L+D+F  FG + E+ +    +  +   FGF+ F D   V KVL+ 
Sbjct: 2   KMFVGGLSWQTSPESLRDYFNKFGEITEVMVMKDPTTRRSRGFGFITFGDPASVDKVLAQ 181
>08958
          Length = 680

 Score = 37.4 bits (85), Expect = 0.014,   Method: Compositional matrix adjust.
 Identities = 21/59 (35%), Positives = 30/59 (50%)
 Frame = +2

Query: 326 VEPRRMVRHPDSHQLFIGNLPHEVDKSELKDFFQNFGNVVELRINSGGKLPNFGFVVFD 384
           V+  R  +     +LF+GNL  +V + + K  F  FG V E  +NSG     FGF+  D
Sbjct: 32  VKEYRRKKFTGRCRLFVGNLTPDVSEDDFKKLFSPFGEVSEAYVNSG---RGFGFIRLD 199
>13457
          Length = 4857

 Score = 34.3 bits (77), Expect(2) = 0.015,   Method: Compositional matrix adjust.
 Identities = 14/37 (37%), Positives = 20/37 (54%)
 Frame = -3

Query: 333  RHPDSHQLFIGNLPHEVDKSELKDFFQNFGNVVELRI 369
            R P+   LFI +LP     +EL   F  FGNV+  ++
Sbjct: 2437 RGPEGCNLFIYHLPQXXGDAELAQMFVPFGNVISAKV 2327

 Score = 21.6 bits (44), Expect(2) = 0.015,   Method: Compositional matrix adjust.
 Identities = 13/39 (33%), Positives = 18/39 (46%)
 Frame = -2

Query: 378  FGFVVFDDSEPVQKVLSNRPIMFRGAVRLNVEEKKTRAA 416
            FGFV FD+    Q  +        G  RL V+ K+ + A
Sbjct: 2294 FGFVSFDNPASAQAAIQAMNGFQIGMKRLKVQLKRPKDA 2178
>15503
          Length = 570

 Score = 36.2 bits (82), Expect = 0.030,   Method: Compositional matrix adjust.
 Identities = 13/46 (28%), Positives = 28/46 (60%)
 Frame = +1

Query: 340 LFIGNLPHEVDKSELKDFFQNFGNVVELRINSGGKLPNFGFVVFDD 385
           L++ NLP+++   E+ D F  +G + ++R+ +  +     FVV++D
Sbjct: 154 LYVKNLPYKITAEEMYDIFGKYGAIRQIRVGNTPETKGTAFVVYED 291
>14637
          Length = 455

 Score = 35.8 bits (81), Expect = 0.037,   Method: Compositional matrix adjust.
 Identities = 23/63 (36%), Positives = 30/63 (47%), Gaps = 3/63 (4%)
 Frame = -1

Query: 335 PDSHQLFIGNLPHEVDKSELKDFFQNFGNVVELR--INSGGKLPN-FGFVVFDDSEPVQK 391
           PD   LFI +LP E    +L   F  FGNV+  +  I+    L   FGFV +D     Q 
Sbjct: 212 PDGSNLFIYHLPQEFGDQDLMQMFMPFGNVISAKVFIDKQTNLSKCFGFVSYDSPMSAQD 33

Query: 392 VLS 394
            +S
Sbjct: 32  AIS 24
>02415
          Length = 2763

 Score = 35.8 bits (81), Expect = 0.037,   Method: Compositional matrix adjust.
 Identities = 15/50 (30%), Positives = 27/50 (54%), Gaps = 3/50 (6%)
 Frame = -1

Query: 339  QLFIGNLPHEVDKSELKDFFQNFGNVVELRINS---GGKLPNFGFVVFDD 385
            ++F+G LP+      L+++F  FG++ E  + +    GK   +GFV   D
Sbjct: 1923 KIFVGGLPYHTTDHSLREYFDKFGDIDEAVVITDRQTGKSRGYGFVTMAD 1774
>10194
          Length = 1278

 Score = 35.8 bits (81), Expect = 0.042,   Method: Compositional matrix adjust.
 Identities = 16/50 (32%), Positives = 26/50 (52%), Gaps = 2/50 (4%)
 Frame = -3

Query: 325 DVEPRR--MVRHPDSHQLFIGNLPHEVDKSELKDFFQNFGNVVELRINSG 372
           D  PRR  + R  +   +F+GN+P + DK +L   F+ FG +  +R    
Sbjct: 757 DKRPRRDRLQRANEKRTVFVGNVPLKTDKKKLARLFKQFGKIENVRFRCA 608

 Score = 34.7 bits (78), Expect = 0.094,   Method: Compositional matrix adjust.
 Identities = 16/66 (24%), Positives = 37/66 (56%), Gaps = 4/66 (6%)
 Frame = -3

Query: 332 VRHPDSHQLFIGNLPHEVDKSELKDFFQNFGNVVELRINSGGKLPNFG----FVVFDDSE 387
           +++ D   +F+GNLP ++++  ++  F++ G+V  +R+    K  N G    +++F  ++
Sbjct: 424 LKNLDKRSVFVGNLPFDIEEESVRSHFEDCGDVENIRVVRDRKT-NLGKGICYILFKSAD 248

Query: 388 PVQKVL 393
            V   L
Sbjct: 247 SVSLAL 230
>04988
          Length = 705

 Score = 35.4 bits (80), Expect = 0.047,   Method: Compositional matrix adjust.
 Identities = 14/47 (29%), Positives = 31/47 (65%)
 Frame = -3

Query: 339 QLFIGNLPHEVDKSELKDFFQNFGNVVELRINSGGKLPNFGFVVFDD 385
           +++IG LP++  + +++ FF+ +G V ++ + +G     +GFV F+D
Sbjct: 649 RVYIGRLPYQAREKDIERFFRGYGRVNDIMLKNG-----YGFVEFED 524
>11687
          Length = 676

 Score = 35.4 bits (80), Expect = 0.049,   Method: Compositional matrix adjust.
 Identities = 16/64 (25%), Positives = 36/64 (56%), Gaps = 2/64 (3%)
 Frame = +3

Query: 322 EPGDVEPRRMVRHPDSHQLFIGNLPHEVDKSELKDFFQNFGNVVELRI--NSGGKLPNFG 379
           +P D E R   R+ +  +LF+G L  ++ +++++  F++FG++ +  +  +S G      
Sbjct: 381 KPADSEKRNGERNVEERKLFVGMLSKKLSENDVRMLFESFGSIDDCTVLRDSNGTSRGCA 560

Query: 380 FVVF 383
           F+ F
Sbjct: 561 FITF 572
>23720
          Length = 739

 Score = 35.4 bits (80), Expect = 0.055,   Method: Compositional matrix adjust.
 Identities = 14/47 (29%), Positives = 31/47 (65%)
 Frame = -1

Query: 339 QLFIGNLPHEVDKSELKDFFQNFGNVVELRINSGGKLPNFGFVVFDD 385
           +++IG LP++  + +++ FF+ +G V ++ + +G     +GFV F+D
Sbjct: 682 RVYIGRLPYQAREKDIERFFRGYGRVNDIMLKNG-----YGFVEFED 557
>03200
          Length = 657

 Score = 34.7 bits (78), Expect = 0.084,   Method: Compositional matrix adjust.
 Identities = 22/65 (33%), Positives = 33/65 (50%)
 Frame = -1

Query: 354 LKDFFQNFGNVVELRINSGGKLPNFGFVVFDDSEPVQKVLSNRPIMFRGAVRLNVEEKKT 413
           LK  F NFGN+V + I    +  N GFV F+  E   + ++N      G++  NV+ K  
Sbjct: 444 LKSAFSNFGNIVNINIE---RERNNGFVTFEKMESADQAIAN----MNGSMISNVQLKVM 286

Query: 414 RAARE 418
            A R+
Sbjct: 285 MARRQ 271
>15371
          Length = 383

 Score = 34.7 bits (78), Expect = 0.090,   Method: Compositional matrix adjust.
 Identities = 22/53 (41%), Positives = 27/53 (50%), Gaps = 3/53 (5%)
 Frame = -2

Query: 335 PDSHQLFIGNLPHEVDKSELKDFFQNFGNVVELR--INSGGKLPN-FGFVVFD 384
           PD   LFI +LP E    +L   F  FGNVV  +  I+    L   FGFV +D
Sbjct: 166 PDGANLFIYHLPQEFGDQDLMQMFMPFGNVVSAKVFIDKQTNLSKCFGFVSYD 8
>16427
          Length = 1313

 Score = 33.1 bits (74), Expect = 0.21,   Method: Compositional matrix adjust.
 Identities = 23/78 (29%), Positives = 40/78 (51%), Gaps = 6/78 (7%)
 Frame = +1

Query: 339 QLFIGNLPHEVDKSELKDFFQNFGNVVE---LRINSGGKLPNFGFVVFD---DSEPVQKV 392
           +LF+G L  E+D+  L+  F  FG + E   +R         FGFV ++   D+E   K 
Sbjct: 139 KLFVGGLAEEIDEKVLEREFSKFGRITESMVIRDKVRQVSRGFGFVTYENPMDAEEAVKH 318

Query: 393 LSNRPIMFRGAVRLNVEE 410
           +  + I+ +   +L+VE+
Sbjct: 319 MDGKEILGK---KLHVED 363
>21096
          Length = 1186

 Score = 32.7 bits (73), Expect = 0.35,   Method: Compositional matrix adjust.
 Identities = 17/55 (30%), Positives = 29/55 (52%)
 Frame = +3

Query: 339 QLFIGNLPHEVDKSELKDFFQNFGNVVELRINSGGKLPNFGFVVFDDSEPVQKVL 393
           +LF+   P  V +  L+D F  FGN++ + + SG    N+G+  + + E   K L
Sbjct: 75  RLFVVCQPGSVPERVLRDAFSRFGNLISVYLLSG---RNYGYAKYANHESAMKAL 230
>24983
          Length = 433

 Score = 32.0 bits (71), Expect = 0.53,   Method: Composition-based stats.
 Identities = 16/51 (31%), Positives = 25/51 (49%), Gaps = 3/51 (5%)
 Frame = -2

Query: 338 HQLFIGNLPHEVDKSELKDFFQNFGNVVELRI---NSGGKLPNFGFVVFDD 385
           HQ  +G LP+      L+++F  FG++ E  +      GK   +GFV   D
Sbjct: 315 HQDLLGGLPYHTTDHSLREYFDKFGDIDEAVVITDRQTGKSRGYGFVTMAD 163
>11108
          Length = 493

 Score = 30.8 bits (68), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 19/76 (25%), Positives = 42/76 (55%), Gaps = 5/76 (6%)
 Frame = -1

Query: 324 GDVEPR--RMVRHPDSHQLFIGNLPHEVDKSELKDFFQNFGNV-VEL--RINSGGKLPNF 378
           G + PR  RM+ +  S ++F+G +P ++ +  L   F+ FG++ VE   +     +   +
Sbjct: 334 GQLPPRSHRMLNY--SPKVFLGGIPWDISEQSLIQIFKPFGSIKVEWPGKEQQAAQPKGY 161

Query: 379 GFVVFDDSEPVQKVLS 394
            +++F+  + V+ +LS
Sbjct: 160 VYIIFESDKQVKALLS 113
>30672
          Length = 877

 Score = 30.0 bits (66), Expect = 1.9,   Method: Compositional matrix adjust.
 Identities = 17/50 (34%), Positives = 25/50 (50%), Gaps = 3/50 (6%)
 Frame = +3

Query: 337 SHQLFIGNLPHEVDKSELKDFFQNFGNVVELRINSG---GKLPNFGFVVF 383
           S  LF+ NLP E    +L + F+  G +    + +G   GK   FG+V F
Sbjct: 9   SKTLFVRNLPFETSNEKLLEAFEQVGPLKTAFVVAGKEPGKCRGFGYVQF 158
>00556
          Length = 2189

 Score = 30.0 bits (66), Expect = 2.0,   Method: Compositional matrix adjust.
 Identities = 19/81 (23%), Positives = 36/81 (44%), Gaps = 3/81 (3%)
 Frame = +3

Query: 338 HQLFIGNLPHEVDKSELKDFFQNFGNVVE---LRINSGGKLPNFGFVVFDDSEPVQKVLS 394
           H++F+G LP  + + ++K+   +FG +     +R N+ G    F F  + D     +  +
Sbjct: 759 HKIFMGGLPSYLSEDQMKELLLSFGPLKSFNLVRDNATGLSKGFAFCEYLDPSVTDQACA 938

Query: 395 NRPIMFRGAVRLNVEEKKTRA 415
               M  G  +L V+     A
Sbjct: 939 GLNGMQLGDKKLIVQRASIGA 1001
>39789
          Length = 361

 Score = 29.3 bits (64), Expect = 3.5,   Method: Compositional matrix adjust.
 Identities = 16/44 (36%), Positives = 21/44 (47%)
 Frame = +1

Query: 340 LFIGNLPHEVDKSELKDFFQNFGNVVELRINSGGKLPNFGFVVF 383
           LF+GNL ++ D+  LKD F         +     K   FGFV F
Sbjct: 94  LFVGNLSYDTDQYSLKDAFPGATAARIAKFQDTQKPRGFGFVEF 225
>36115
          Length = 396

 Score = 29.3 bits (64), Expect = 3.9,   Method: Composition-based stats.
 Identities = 17/44 (38%), Positives = 25/44 (56%), Gaps = 2/44 (4%)
 Frame = -3

Query: 317 IREAGEPGDVEPRRMVRHPDSHQLFIGNLPHEVDKS--ELKDFF 358
           ++E  +  DVE RRM++H  +  L IG   H + +S   LK FF
Sbjct: 241 LKELQDLHDVEQRRMLKHGCTRWLSIGRCIHRLLESWDPLKQFF 110
>33504
          Length = 282

 Score = 28.1 bits (61), Expect = 7.0,   Method: Composition-based stats.
 Identities = 10/36 (27%), Positives = 22/36 (61%)
 Frame = +1

Query: 334 HPDSHQLFIGNLPHEVDKSELKDFFQNFGNVVELRI 369
           + DS  +FIG LP+++ + ++   F  +G +V + +
Sbjct: 157 YKDSAWVFIGGLPYDLTEGDIICVFSQYGEIVNINL 264
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|35215309|ref|NP_874385.1| neurofascin [Mus musculus]
         (1240 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

35419                                                                  67   3e-20
19544                                                                  72   2e-12
25455                                                                  65   1e-10
06028                                                                  65   2e-10
29990                                                                  62   1e-09
08294                                                                  59   1e-08
13135                                                                  58   2e-08
20110                                                                  55   3e-08
26757                                                                  55   2e-07
17229                                                                  54   3e-07
36498                                                                  43   6e-07
36700                                                                  53   1e-06
11855                                                                  50   6e-06
37675                                                                  45   2e-04
17530                                                                  44   4e-04
34369                                                                  41   0.003
19356                                                                  40   0.004
38127                                                                  40   0.005
18345                                                                  40   0.006
27666                                                                  39   0.010
25766                                                                  34   0.010
32888                                                                  32   0.013
17679                                                                  38   0.027
07945                                                                  37   0.040
12764                                                                  36   0.090
20244                                                                  28   0.091
29932                                                                  34   0.28 
10921                                                                  33   0.93 
29881                                                                  32   1.1  
11732                                                                  32   2.3  
07940                                                                  31   2.5  
05091                                                                  30   6.8  
>35419
          Length = 623

 Score = 67.4 bits (163), Expect(2) = 3e-20,   Method: Compositional matrix adjust.
 Identities = 47/147 (31%), Positives = 71/147 (48%), Gaps = 5/147 (3%)
 Frame = -2

Query: 516 LEVKDPTRIYRMPEDQVAKRGTTVQLECRVKHDPS--LKLTVSWLKDDEPL-YIGNRMKK 572
           L V+  T+I + P D     GT  +  C    DP     L + W+KD++ +  +  RM  
Sbjct: 592 LLVRRKTQIEQAPMDLEVNAGTDAKFTCSGTTDPEEVHMLKIKWMKDNKEISTVEQRMTT 413

Query: 573 --EDDSLTIFGVAERDQGSYTCMASTELDQDLAKAYLTVLADQATPTNRLAALPKGRPDR 630
             +D+SLTI G   RD G+YTC+++  LD   A A LTV               K RPD 
Sbjct: 412 NIQDNSLTISGTIVRDSGTYTCISTNGLDSAEASAMLTV---------------KDRPDV 278

Query: 631 PRDLELTDLAERSVRLTWIPGDDNNSP 657
             ++++    + +  L W+PG  NN+P
Sbjct: 277 ASEVKIEKCDDNATIL-WMPGSYNNAP 200

 Score = 50.4 bits (119), Expect(2) = 3e-20,   Method: Compositional matrix adjust.
 Identities = 27/60 (45%), Positives = 35/60 (58%)
 Frame = -1

Query: 657 PITDYVVQFEEDQFQPGVWHDHSRFPGSVNSAVLHLSPYVNYQFRVIAVNEVGSSHPSLP 716
           P+  YV+Q+    F P  W    +      SA + LSP+VNY FRVIA N++G S PSLP
Sbjct: 203 PVQYYVIQYNTS-FNPDTWTFAVQVDSIFTSANVSLSPWVNYTFRVIAYNKIGESDPSLP 27

 Score = 36.2 bits (82), Expect = 0.093,   Method: Compositional matrix adjust.
 Identities = 21/60 (35%), Positives = 30/60 (50%), Gaps = 1/60 (1%)
 Frame = -2

Query: 462 LRWFK-NGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKD 520
           ++W K N + S ++       ++ SL I      D G YTC++TN L  AE    L VKD
Sbjct: 469 IKWMKDNKEISTVEQRMTTNIQDNSLTISGTIVRDSGTYTCISTNGLDSAEASAMLTVKD 290

 Score = 33.1 bits (74), Expect = 0.68,   Method: Compositional matrix adjust.
 Identities = 17/91 (18%), Positives = 38/91 (41%), Gaps = 4/91 (4%)
 Frame = -2

Query: 343 PKNLILAPGEDGRLVCRANGNPKPT----VQWMVNGEPLQSAPPNPNREVAGDTIIFRDT 398
           P +L +  G D +  C    +P+      ++WM + + + +        +  +++    T
Sbjct: 556 PMDLEVNAGTDAKFTCSGTTDPEEVHMLKIKWMKDNKEISTVEQRMTTNIQDNSLTISGT 377

Query: 399 QISSRAVYQCNTSNEHGYLLANAFVSVLDVP 429
            +     Y C ++N      A+A ++V D P
Sbjct: 376 IVRDSGTYTCISTNGLDSAEASAMLTVKDRP 284
>19544
          Length = 1421

 Score = 71.6 bits (174), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 54/215 (25%), Positives = 101/215 (46%), Gaps = 5/215 (2%)
 Frame = +2

Query: 697 NYQFRVIAVNEVGSSHPSLPSERYRTSGAPPESNPSDVKGEGTRKNNMEITWT-PMNATS 755
            Y+ +V+AVN  G   PS P+  Y    AP E  PS+V+      +++++TW  P   T 
Sbjct: 17  TYEVQVLAVNGKGRGPPSTPATIYVGEAAPTE-GPSNVQAVNKSASSIQVTWVAPPPETQ 193

Query: 756 AFGPNLRYIVKWRRRETRETWNNVTVWGSRYVVGQTPVYVPYEIRVQAENDFGKGPEPDT 815
             G +   ++ +++  + E         +  ++     +  Y I VQ  N  G+GP    
Sbjct: 194 NGGLSGYKVLYYKQSSSAEEELTRITAETHILLESLETFTVYFIAVQPYNLAGEGPRSAL 373

Query: 816 IIGYSGEDLPSAPRRFRVRQPNLETINLEWDHPEHPNGILIGYILRYVPFNGTKLG---- 871
           +   + E +PSAP+  R     +  + + +D P  PNG ++ Y ++Y P + ++ G    
Sbjct: 374 VSAQTSEGVPSAPQSIRFTNITMRQLMVHFDPPTTPNGHILLYEMQYFPKDESRYGFLAP 553

Query: 872 KQMVENFSPNQTKFSVQRADPVSRYRFSLSARTQV 906
           K+++     N+T+  V   +    Y+F +SA T +
Sbjct: 554 KRILRA---NETRVVVTELEKRVWYKFIISANTSI 649

 Score = 37.0 bits (84), Expect = 0.045,   Method: Compositional matrix adjust.
 Identities = 18/31 (58%), Positives = 22/31 (70%)
 Frame = +2

Query: 692 LSPYVNYQFRVIAVNEVGSSHPSLPSERYRT 722
           L+P   YQFRV+A+N+ G S  SLPSER  T
Sbjct: 896 LNPNTGYQFRVMAINDDGISDESLPSERVVT 988
>25455
          Length = 444

 Score = 65.5 bits (158), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 36/122 (29%), Positives = 57/122 (46%), Gaps = 9/122 (7%)
 Frame = +1

Query: 314 YFCLASNKMGSIR---HTISVRVKAAPYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQW 370
           Y C A + +  I      + V V++AP W+  P+   +  GE   + C A   P P   W
Sbjct: 1   YRCWAESTVHHINFPLREMRVVVQSAPSWVVAPQVTEVEVGETAEITCNATAIPDPVTNW 180

Query: 371 MVNGEPLQSAPPNPNR------EVAGDTIIFRDTQISSRAVYQCNTSNEHGYLLANAFVS 424
            VNG  +     +  R      ++  D +I R+  I  R V QCN +N +G+L A+  ++
Sbjct: 181 FVNGREISDVVEHDVRFQSGRFDLTSDRLILRNVTIEGRMVVQCNVTNRYGHLWADVSLN 360

Query: 425 VL 426
           VL
Sbjct: 361 VL 366
>06028
          Length = 1358

 Score = 64.7 bits (156), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 71/270 (26%), Positives = 113/270 (41%), Gaps = 27/270 (10%)
 Frame = +1

Query: 173 IFWMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQTD---YSC-----NARFHFTHTIQ 224
           I WM  + EPI+ D++  Q    D Y   ++   ++ D   Y C      A+   +H + 
Sbjct: 4   IQWMKGT-EPISNDEKYQQVDQADGYSKLIIHNPVEKDSGVYFCVASNEGAQNKISHQVD 180

Query: 225 QKNPFTLKVLTTRGVAERTPS---FMYPQGTSSSQMVLRGMDLLL--ECIASGVPTPDIA 279
            K      +  T G   R P+   F+ P G   +Q V  G  + +  E + S  P  ++ 
Sbjct: 181 FKGRERFTLEKTAGFFHRDPNKPHFLNPLG---NQTVCHGGTVAISAEFMQSSTPI-EVK 348

Query: 280 WYKKGGDLPSNKAKFENFNK----ALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKA 335
           W +     P +    + FN+     L I N  EE  G Y CLASN  G I   +++ V  
Sbjct: 349 WLRN--RRPVDGPSVQTFNERGIYTLAIMNAGEEHEGTYTCLASNAFGRIESHVNIDVAV 522

Query: 336 A-------PYWLDEPKN-LILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNRE 387
                   P +L  P+  + +A G+   L  R  G+PKP + +M  G    +     ++E
Sbjct: 523 GVEKEVRPPLFLSRPETEMKIAVGDPFSLSFRIAGDPKPRLVFM-KGTKDITQSDRVSKE 699

Query: 388 VAGDTIIF--RDTQISSRAVYQCNTSNEHG 415
           V+ D   F  + +QIS    Y     N+ G
Sbjct: 700 VSDDYTRFTVQKSQISDSGTYFVVARNDFG 789

 Score = 47.4 bits (111), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 63/278 (22%), Positives = 108/278 (38%), Gaps = 32/278 (11%)
 Frame = +1

Query: 278 IAWYKKGGDLPSNKAKFENFNKA-----LRITNVSEEDSGEYFCLASNK--MGSIRHTIS 330
           I W K G +  SN  K++  ++A     L I N  E+DSG YFC+ASN+     I H + 
Sbjct: 4   IQWMK-GTEPISNDEKYQQVDQADGYSKLIIHNPVEKDSGVYFCVASNEGAQNKISHQVD 180

Query: 331 VRVKA----------------APYWLDEPKNLILAPGEDGRLVCRANGNPKPT-VQWMVN 373
            + +                  P++L+   N  +  G    +      +  P  V+W+ N
Sbjct: 181 FKGRERFTLEKTAGFFHRDPNKPHFLNPLGNQTVCHGGTVAISAEFMQSSTPIEVKWLRN 360

Query: 374 GEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVL-----DV 428
             P+         E    T+   +        Y C  SN  G + ++  + V      +V
Sbjct: 361 RRPVDGPSVQTFNERGIYTLAIMNAGEEHEGTYTCLASNAFGRIESHVNIDVAVGVEKEV 540

Query: 429 -PPRMLSARNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQG-SNLDGGNYHVYENGS- 485
            PP  LS     +++ + +   L     G P P L + K  +  +  D  +  V ++ + 
Sbjct: 541 RPPLFLSRPETEMKIAVGDPFSLSFRIAGDPKPRLVFMKGTKDITQSDRVSKEVSDDYTR 720

Query: 486 LEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTR 523
             ++  +  D G Y  VA N  G     V + +K P +
Sbjct: 721 FTVQKSQISDSGTYFVVARNDFGTDRIFVTITIKTPKK 834

 Score = 38.1 bits (87), Expect = 0.020,   Method: Compositional matrix adjust.
 Identities = 41/159 (25%), Positives = 63/159 (39%), Gaps = 16/159 (10%)
 Frame = +1

Query: 49  KDHIVDPRDN--------ILIECEAKGNPAP-SFHWTRNSRFFNIAKDPRVSMRRRSGTL 99
           K H ++P  N        + I  E   +  P    W RN R       P V      G  
Sbjct: 244 KPHFLNPLGNQTVCHGGTVAISAEFMQSSTPIEVKWLRNRR---PVDGPSVQTFNERGIY 414

Query: 100 VIDFRSGGRPEEYEGEYQCFARNKFGTALSNRIRLQVS-------KSPLWPKENLDPVVV 152
            +   + G  EE+EG Y C A N FG  + + + + V+       + PL+       + +
Sbjct: 415 TLAIMNAG--EEHEGTYTCLASNAFGR-IESHVNIDVAVGVEKEVRPPLFLSRPETEMKI 585

Query: 153 QEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQ 191
             G P +L      G P P + +M  + + ITQ  RVS+
Sbjct: 586 AVGDPFSLSFR-IAGDPKPRLVFMKGTKD-ITQSDRVSK 696

 Score = 35.8 bits (81), Expect = 0.10,   Method: Compositional matrix adjust.
 Identities = 30/129 (23%), Positives = 55/129 (42%), Gaps = 23/129 (17%)
 Frame = +1

Query: 493 KEDQGIYTCVATNILGKAENQVRLEV------------------KDPTRIYRMP--EDQV 532
           ++D G+Y CVA+N    A+N++  +V                  +DP + + +    +Q 
Sbjct: 106 EKDSGVYFCVASN--EGAQNKISHQVDFKGRERFTLEKTAGFFHRDPNKPHFLNPLGNQT 279

Query: 533 AKRGTTVQLECRVKHDPSLKLTVSWLKDDEPL---YIGNRMKKEDDSLTIFGVAERDQGS 589
              G TV +        S  + V WL++  P+    +    ++   +L I    E  +G+
Sbjct: 280 VCHGGTVAISAEFMQS-STPIEVKWLRNRRPVDGPSVQTFNERGIYTLAIMNAGEEHEGT 456

Query: 590 YTCMASTEL 598
           YTC+AS   
Sbjct: 457 YTCLASNAF 483

 Score = 32.0 bits (71), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 20/85 (23%), Positives = 35/85 (41%), Gaps = 5/85 (5%)
 Frame = +1

Query: 555 VSWLKDDEPLYIGNRMKKEDDS-----LTIFGVAERDQGSYTCMASTELDQDLAKAYLTV 609
           + W+K  EP+    + ++ D +     L I    E+D G Y C+AS E  Q+     +  
Sbjct: 4   IQWMKGTEPISNDEKYQQVDQADGYSKLIIHNPVEKDSGVYFCVASNEGAQNKISHQVDF 183

Query: 610 LADQATPTNRLAALPKGRPDRPRDL 634
              +     + A      P++P  L
Sbjct: 184 KGRERFTLEKTAGFFHRDPNKPHFL 258
>29990
          Length = 434

 Score = 62.4 bits (150), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 37/125 (29%), Positives = 61/125 (48%), Gaps = 7/125 (5%)
 Frame = +3

Query: 272 GVPTPDIAWYKKGGDLP-SNKAKFENFNKA-LRITNVSEEDSGEYFCLASNKMGSIRHTI 329
           G P P+I W      +  S  ++F   +   L I +  ++D G Y C+A N  G   H+ 
Sbjct: 6   GKPVPEIVWMHNNNRVEISGDSRFSLLHDGTLMIEDAQDDDRGVYECIARNVAGET-HSN 182

Query: 330 SVRVK-----AAPYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNP 384
            V ++      AP +   P++++   G+  +LVC+A+G+P+PT  W  N E L S   +P
Sbjct: 183 QVELRYFGERVAPXFTQRPQDIVTVEGQTVQLVCQASGHPRPTFSWTRNLEQLGSTLVSP 362

Query: 385 NREVA 389
               A
Sbjct: 363 TTRTA 377

 Score = 58.2 bits (139), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 38/115 (33%), Positives = 59/115 (51%), Gaps = 6/115 (5%)
 Frame = +3

Query: 456 GSPIPTLRWFKNGQGSNLDGGN-YHVYENGSLEIKMIRKEDQGIYTCVATNILGKAE-NQ 513
           G P+P + W  N     + G + + +  +G+L I+  + +D+G+Y C+A N+ G+   NQ
Sbjct: 6   GKPVPEIVWMHNNNRVEISGDSRFSLLHDGTLMIEDAQDDDRGVYECIARNVAGETHSNQ 185

Query: 514 VRL----EVKDPTRIYRMPEDQVAKRGTTVQLECRVKHDPSLKLTVSWLKDDEPL 564
           V L    E   P    R P+D V   G TVQL C+    P  + T SW ++ E L
Sbjct: 186 VELRYFGERVAPXFTQR-PQDIVTVEGQTVQLVCQASGHP--RPTFSWTRNLEQL 341

 Score = 48.1 bits (113), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 34/112 (30%), Positives = 49/112 (43%), Gaps = 2/112 (1%)
 Frame = +3

Query: 66  KGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQCFARNKFG 125
           +G P P   W  N+    I+ D R S+    GTL+I+       ++  G Y+C ARN  G
Sbjct: 3   EGKPVPEIVWMHNNNRVEISGDSRFSLLH-DGTLMIE----DAQDDDRGVYECIARNVAG 167

Query: 126 TALSNRIRLQVSKSPLWPKENLDP--VVVQEGAPLTLQCNPPPGLPSPVIFW 175
              SN++ L+     + P     P  +V  EG  + L C    G P P   W
Sbjct: 168 ETHSNQVELRYFGERVAPXFTQRPQDIVTVEGQTVQLVCQ-ASGHPRPTFSW 320

 Score = 38.1 bits (87), Expect(2) = 4e-04,   Method: Compositional matrix adjust.
 Identities = 40/129 (31%), Positives = 52/129 (40%), Gaps = 6/129 (4%)
 Frame = +3

Query: 167 GLPSPVIFWMSSSME-PITQDKRVSQGHNGDLYFSNVMLQDMQTD----YSCNARFHFTH 221
           G P P I WM ++    I+ D R S  H+G L     M++D Q D    Y C AR     
Sbjct: 6   GKPVPEIVWMHNNNRVEISGDSRFSLLHDGTL-----MIEDAQDDDRGVYECIARNVAGE 170

Query: 222 TIQQKNPFTLKVLTTRGVAERTPSFMY-PQGTSSSQMVLRGMDLLLECIASGVPTPDIAW 280
           T    N   L+    R      P F   PQ      + + G  + L C ASG P P  +W
Sbjct: 171 T--HSNQVELRYFGER----VAPXFTQRPQDI----VTVEGQTVQLVCQASGHPRPTFSW 320

Query: 281 YKKGGDLPS 289
            +    L S
Sbjct: 321 TRNLEQLGS 347

 Score = 25.0 bits (53), Expect(2) = 4e-04,   Method: Compositional matrix adjust.
 Identities = 10/24 (41%), Positives = 14/24 (58%)
 Frame = +2

Query: 295 ENFNKALRITNVSEEDSGEYFCLA 318
           ++ +  L I NV E D G+Y C A
Sbjct: 362 DHEDGTLTIRNVQESDRGDYQCYA 433

 Score = 39.7 bits (91), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 29/109 (26%), Positives = 45/109 (41%), Gaps = 3/109 (2%)
 Frame = +3

Query: 362 GNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHGYLLANA 421
           G P P + WM N   ++ +  +    +   T++  D Q   R VY+C   N  G   +N 
Sbjct: 6   GKPVPEIVWMHNNNRVEISGDSRFSLLHDGTLMIEDAQDDDRGVYECIARNVAGETHSNQ 185

Query: 422 FVSVLDVPPRM---LSARNQLIRVILYNRTRLDCPFFGSPIPTLRWFKN 467
            V +     R+    + R Q I  +     +L C   G P PT  W +N
Sbjct: 186 -VELRYFGERVAPXFTQRPQDIVTVEGQTVQLVCQASGHPRPTFSWTRN 329

 Score = 31.6 bits (70), Expect = 1.8,   Method: Compositional matrix adjust.
 Identities = 13/31 (41%), Positives = 19/31 (61%), Gaps = 7/31 (22%)
 Frame = +3

Query: 55  PRDNILIE-------CEAKGNPAPSFHWTRN 78
           P+D + +E       C+A G+P P+F WTRN
Sbjct: 237 PQDIVTVEGQTVQLVCQASGHPRPTFSWTRN 329
>08294
          Length = 1849

 Score = 58.9 bits (141), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 37/119 (31%), Positives = 58/119 (48%), Gaps = 1/119 (0%)
 Frame = +2

Query: 253 SSSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSNKAKFENF-NKALRITNVSEEDS 311
           S++  V  G   +L C+A G P+PDIAWY+    +  N  ++  F N  ++I  V  ED+
Sbjct: 95  SNNITVFEGHSAILHCVAKGSPSPDIAWYRDSQPILPNARRYTLFKNGTMKIRQVFMEDN 274

Query: 312 GEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQW 370
           G Y C+A+N  G +  T S  ++   +W     +    P      +C A   P PT+ W
Sbjct: 275 GMYACVANNTAGPLAGTSSFALRTM-HWRRMKTSTW*RPSSS---LCVA---PAPTLPW 430

 Score = 55.1 bits (131), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 30/104 (28%), Positives = 54/104 (51%), Gaps = 1/104 (0%)
 Frame = +2

Query: 406 YQCNTSN-EHGYLLANAFVSVLDVPPRMLSARNQLIRVILYNRTRLDCPFFGSPIPTLRW 464
           Y C  ++   G + A   +S+++ P   + + N  I V   +   L C   GSP P + W
Sbjct: 5   YTCVATHPRQGVINATIHISIVEWPAITVKSNN--ITVFEGHSAILHCVAKGSPSPDIAW 178

Query: 465 FKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILG 508
           +++ Q    +   Y +++NG+++I+ +  ED G+Y CVA N  G
Sbjct: 179 YRDSQPILPNARRYTLFKNGTMKIRQVFMEDNGMYACVANNTAG 310

 Score = 42.0 bits (97), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 28/108 (25%), Positives = 47/108 (43%), Gaps = 3/108 (2%)
 Frame = +2

Query: 313 EYFCLASN-KMGSIRHTISVRVKAAPYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWM 371
           +Y C+A++ + G I  TI + +   P    +  N+ +  G    L C A G+P P + W 
Sbjct: 2   DYTCVATHPRQGVINATIHISIVEWPAITVKSNNITVFEGHSAILHCVAKGSPSPDIAWY 181

Query: 372 VNGEPLQSAPPNPNREV--AGDTIIFRDTQISSRAVYQCNTSNEHGYL 417
            + +P+    PN  R       T+  R   +    +Y C  +N  G L
Sbjct: 182 RDSQPIL---PNARRYTLFKNGTMKIRQVFMEDNGMYACVANNTAGPL 316

 Score = 35.0 bits (79), Expect = 0.21,   Method: Compositional matrix adjust.
 Identities = 29/99 (29%), Positives = 45/99 (45%), Gaps = 2/99 (2%)
 Frame = +2

Query: 29  MDPSIQNELTQPPTITKQSVKDHIVDPRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDP 88
           ++ +I   + + P IT +S    + +    IL  C AKG+P+P   W R+S+   I  + 
Sbjct: 41  INATIHISIVEWPAITVKSNNITVFEGHSAIL-HCVAKGSPSPDIAWYRDSQ--PILPNA 211

Query: 89  RVSMRRRSGTLVID--FRSGGRPEEYEGEYQCFARNKFG 125
           R     ++GT+ I   F       E  G Y C A N  G
Sbjct: 212 RRYTLFKNGTMKIRQVFM------EDNGMYACVANNTAG 310

 Score = 32.7 bits (73), Expect = 1.0,   Method: Compositional matrix adjust.
 Identities = 26/103 (25%), Positives = 43/103 (41%), Gaps = 2/103 (1%)
 Frame = +2

Query: 115 EYQCFARNKFGTALSNRIRLQVSKSPLWPKENL--DPVVVQEGAPLTLQCNPPPGLPSPV 172
           +Y C A +     ++  I + + +   WP   +  + + V EG    L C    G PSP 
Sbjct: 2   DYTCVATHPRQGVINATIHISIVE---WPAITVKSNNITVFEGHSAILHC-VAKGSPSPD 169

Query: 173 IFWMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNA 215
           I W   S   +   +R +   NG +    V ++D    Y+C A
Sbjct: 170 IAWYRDSQPILPNARRYTLFKNGTMKIRQVFMED-NGMYACVA 295
>13135
          Length = 849

 Score = 58.2 bits (139), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 40/115 (34%), Positives = 51/115 (44%)
 Frame = -1

Query: 252 TSSSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSNKAKFENFNKALRITNVSEEDS 311
           TSS      G  L+L C ASG PTP + W +  G+L  +  + E+    L I  +  E +
Sbjct: 363 TSSDVSKSEGQSLVLRCHASGRPTPSVKWTRMAGELLPSGGR-EHLESDLVIPQLKPEHA 187

Query: 312 GEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNLILAPGEDGRLVCRANGNPKP 366
           G Y C +SN  GS    I V V  AP        +  A G    LVC   G P P
Sbjct: 186 GIYKCSSSNSAGSDFRNIRVTVNFAPVLSSANTVVQQAQGYVKELVCVVKGYPTP 22

 Score = 48.1 bits (113), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 44/164 (26%), Positives = 70/164 (42%), Gaps = 4/164 (2%)
 Frame = -1

Query: 301 LRITNVSEEDSGEYFC---LASNKMGSIRHTISVRVKAAPYWLDEPKNLILAPGEDGRLV 357
           LRI N    D G Y C   L++       H + +        LD   ++  + G+   L 
Sbjct: 495 LRIQNGQVTDEGVYTCQVQLSNQNYAKAFHQLVIIQMPQISDLDTSSDVSKSEGQSLVLR 316

Query: 358 CRANGNPKPTVQWM-VNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHGY 416
           C A+G P P+V+W  + GE L    P+  RE     ++    +     +Y+C++SN  G 
Sbjct: 315 CHASGRPTPSVKWTRMAGELL----PSGGREHLESDLVIPQLKPEHAGIYKCSSSNSAGS 148

Query: 417 LLANAFVSVLDVPPRMLSARNQLIRVILYNRTRLDCPFFGSPIP 460
              N  V+V   P  +LS+ N +++        L C   G P P
Sbjct: 147 DFRNIRVTVNFAP--VLSSANTVVQQAQGYVKELVCVVKGYPTP 22

 Score = 36.2 bits (82), Expect = 0.080,   Method: Compositional matrix adjust.
 Identities = 27/103 (26%), Positives = 43/103 (41%)
 Frame = -1

Query: 450 LDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGK 509
           L C   G P P+++W +        GG  H+  +  L I  ++ E  GIY C ++N  G 
Sbjct: 321 LRCHASGRPTPSVKWTRMAGELLPSGGREHLESD--LVIPQLKPEHAGIYKCSSSNSAGS 148

Query: 510 AENQVRLEVKDPTRIYRMPEDQVAKRGTTVQLECRVKHDPSLK 552
               +R+ V     +          +G   +L C VK  P+ K
Sbjct: 147 DFRNIRVTVNFAPVLSSANTVVQQAQGYVKELVCVVKGYPTPK 19

 Score = 35.4 bits (80), Expect = 0.16,   Method: Compositional matrix adjust.
 Identities = 30/110 (27%), Positives = 44/110 (40%), Gaps = 12/110 (10%)
 Frame = -1

Query: 58  NILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPE------- 110
           ++++ C A G P PS  WT                 R +G L     SGGR         
Sbjct: 330 SLVLRCHASGRPTPSVKWT-----------------RMAGEL---LPSGGREHLESDLVI 211

Query: 111 -----EYEGEYQCFARNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQEG 155
                E+ G Y+C + N  G+   N IR+ V+ +P+    N    VVQ+ 
Sbjct: 210 PQLKPEHAGIYKCSSSNSAGSDFRN-IRVTVNFAPVLSSAN---TVVQQA 73
>20110
          Length = 820

 Score = 54.7 bits (130), Expect(2) = 3e-08,   Method: Compositional matrix adjust.
 Identities = 40/130 (30%), Positives = 61/130 (46%), Gaps = 2/130 (1%)
 Frame = -1

Query: 211 YSCNARFHFTHTIQQKNPFTLKVLTTRGVAERTPSFMYPQGTSSSQMVLRGMDLLLECIA 270
           Y+C  R   T    ++ P  +  LT +      P  + P  T++   + +G +  L C A
Sbjct: 634 YTCTVRI--TAVSYEEWPTKIGNLTVQ-----VPPSIKPGDTTAVLQIEQGQNSTLVCAA 476

Query: 271 SGVPTPDIAWYKK-GGDLPSNKAKFENFNKALRITNVSEEDSGEYFCLASNKMG-SIRHT 328
           SG+P P+I W +  GG LP   A+F   +  L + NV+  D G Y C+A N +     H 
Sbjct: 475 SGIPAPNITWTRSDGGFLPIGVAQFR--SATLPMNNVTVRDMGVYRCVADNNIKPPAEHL 302

Query: 329 ISVRVKAAPY 338
             V V  AP+
Sbjct: 301 AEVLVFHAPF 272

 Score = 22.7 bits (47), Expect(2) = 3e-08,   Method: Compositional matrix adjust.
 Identities = 8/15 (53%), Positives = 10/15 (66%)
 Frame = -3

Query: 356 LVCRANGNPKPTVQW 370
           L C   G+P+PTV W
Sbjct: 215 LECIVKGHPEPTVTW 171

 Score = 30.8 bits (68), Expect = 3.3,   Method: Compositional matrix adjust.
 Identities = 20/71 (28%), Positives = 28/71 (39%), Gaps = 17/71 (23%)
 Frame = -3

Query: 266 LECIASGVPTPDIAW----------YKKGGDLPSNKAKFENFN-------KALRITNVSE 308
           LECI  G P P + W               D   NK   +N N         L++ NV  
Sbjct: 215 LECIVKGHPEPTVTWEMAINNGRFPITDHDDFVINKLTTDNQNLKAGEQWYTLKVKNVLG 36

Query: 309 EDSGEYFCLAS 319
            D  +Y+C+A+
Sbjct: 35  NDFTDYYCIAT 3

 Score = 30.8 bits (68), Expect = 3.9,   Method: Compositional matrix adjust.
 Identities = 17/60 (28%), Positives = 27/60 (45%), Gaps = 4/60 (6%)
 Frame = -1

Query: 450 LDCPFFGSPIPTLRWFKNGQGSNLDGGNYHV----YENGSLEIKMIRKEDQGIYTCVATN 505
           L C   G P P + W ++      DGG   +    + + +L +  +   D G+Y CVA N
Sbjct: 490 LVCAASGIPAPNITWTRS------DGGFLPIGVAQFRSATLPMNNVTVRDMGVYRCVADN 329

 Score = 30.0 bits (66), Expect = 6.4,   Method: Compositional matrix adjust.
 Identities = 20/80 (25%), Positives = 33/80 (41%), Gaps = 10/80 (12%)
 Frame = -1

Query: 301 LRITNVSEEDSGEYFCLAS----------NKMGSIRHTISVRVKAAPYWLDEPKNLILAP 350
           L +  + E D+G Y C              K+G++   +   +K      D    L +  
Sbjct: 673 LVVRRLVETDAGIYTCTVRITAVSYEEWPTKIGNLTVQVPPSIKPG----DTTAVLQIEQ 506

Query: 351 GEDGRLVCRANGNPKPTVQW 370
           G++  LVC A+G P P + W
Sbjct: 505 GQNSTLVCAASGIPAPNITW 446
>26757
          Length = 392

 Score = 55.1 bits (131), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 35/114 (30%), Positives = 53/114 (46%), Gaps = 3/114 (2%)
 Frame = -2

Query: 1102 QADIATQGWFIGLMCXXXXXXXXXXXXCFIKRSRGGKYPVREKKDVPLGPEDPKEEDGSF 1161
            +  + + GWFIG+M             C +KR+RG +Y    +KD         E  G F
Sbjct: 346  KGSVLSAGWFIGMMVAIAILLLILIIVCIVKRNRGKEYKFPPEKDTT------DETPGHF 185

Query: 1162 DYSDEDNKPLQGSQTSLD---GTIKQQESDDSLVDYGEGGEGQFNEDGSFIGQY 1212
            +   +  K    +  S +     +  ++  DSL +YG+    +FNEDGSFIGQY
Sbjct: 184  NEMAKSEKNGLNTSASFERDPEKVPLEDETDSLEEYGDVDPAKFNEDGSFIGQY 23
>17229
          Length = 487

 Score = 54.3 bits (129), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 36/115 (31%), Positives = 55/115 (47%), Gaps = 6/115 (5%)
 Frame = +1

Query: 797 YEIRVQAENDFGKGPEPDTIIGYSGEDLPSAPRRFRVRQPNLETINLEWDHPEHPNGILI 856
           Y I+V A+   G+GP   TI   +   LP  PR+ R    N   I +EWD P+   G + 
Sbjct: 91  YYIQVSAKTVHGEGPRTPTIQTKTLPFLPGEPRKLRAETINSTGIFVEWDEPKDSRGKIR 270

Query: 857 GYILRYVPFNGTK------LGKQMVENFSPNQTKFSVQRADPVSRYRFSLSARTQ 905
           GY + YV  NG++      L +Q+ +  S    +  +   D  SRYR  ++  T+
Sbjct: 271 GYYVYYVKVNGSRDEPPSGLTEQVHDTVSGRVKEAVIIGLDADSRYRVQVAGYTR 435
>36498
          Length = 478

 Score = 42.7 bits (99), Expect(2) = 6e-07,   Method: Compositional matrix adjust.
 Identities = 25/75 (33%), Positives = 35/75 (46%), Gaps = 4/75 (5%)
 Frame = +3

Query: 300 ALRITNVSEEDSGEYFCLASNKMGSIRHTISV---RVKAAPYW-LDEPKNLILAPGEDGR 355
            LR   VSE D+G Y C+A N+ G     + +   R   AP   +D P   +L  G+   
Sbjct: 228 GLRFDPVSEGDAGRYVCVARNERGITEENVDLTVTRTGVAPQVNIDGPGRQMLVDGQSVE 407

Query: 356 LVCRANGNPKPTVQW 370
           L C A G   P ++W
Sbjct: 408 LSCSARGLRNPLIRW 452

 Score = 30.0 bits (66), Expect(2) = 6e-07,   Method: Composition-based stats.
 Identities = 17/52 (32%), Positives = 26/52 (50%)
 Frame = +1

Query: 234 LTTRGVAERTPSFMYPQGTSSSQMVLRGMDLLLECIASGVPTPDIAWYKKGG 285
           LT   V +  P+     GT  + +V   +D+  EC+A G PTP + W +  G
Sbjct: 22  LTASLVIQGPPTVTVTPGTRITALVGDRVDI--ECVAEGDPTPTVFWRRIEG 171

 Score = 30.8 bits (68), Expect = 3.4,   Method: Composition-based stats.
 Identities = 14/38 (36%), Positives = 19/38 (50%)
 Frame = +1

Query: 40 PPTITKQSVKDHIVDPRDNILIECEAKGNPAPSFHWTR 77
          PPT+T            D + IEC A+G+P P+  W R
Sbjct: 49 PPTVTVTPGTRITALVGDRVDIECVAEGDPTPTVFWRR 162
>36700
          Length = 595

 Score = 52.8 bits (125), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 38/131 (29%), Positives = 58/131 (44%), Gaps = 12/131 (9%)
 Frame = +1

Query: 266 LECIASGVPT------PDIAWYKKGGDLPSNKAKF--ENFNKALRITNVSEEDSGEYFCL 317
           LEC+ SG  +      P I W++   D  S   +F  E+  + L I NV E+D   Y C 
Sbjct: 19  LECVFSGYSSTPNNQVPAITWWETSTDQISTGGRFSIEDNGRVLVIDNVDEQDEKTYTCK 198

Query: 318 ASNKMGSIRHTISVRVKAAPYWLDEPKNLILAPGEDGRLVC---RANGNPKPT-VQWMVN 373
             N  GS    + + V + P ++   ++L +  G+D    C    A+G   P    W  N
Sbjct: 199 GENPAGSHSGNLHLNVTSPPIFMQHLQSLTVPQGKDAYFNCVTRSASGEKPPNPPTWYRN 378

Query: 374 GEPLQSAPPNP 384
           G  L + P +P
Sbjct: 379 GLRLDNTPLSP 411

 Score = 41.6 bits (96), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 24/109 (22%), Positives = 44/109 (40%), Gaps = 7/109 (6%)
 Frame = +1

Query: 445 YNRTRLDCPFFG------SPIPTLRWFKNGQGSNLDGGNYHVYENGS-LEIKMIRKEDQG 497
           ++  RL+C F G      + +P + W++        GG + + +NG  L I  + ++D+ 
Sbjct: 4   HSTARLECVFSGYSSTPNNQVPAITWWETSTDQISTGGRFSIEDNGRVLVIDNVDEQDEK 183

Query: 498 IYTCVATNILGKAENQVRLEVKDPTRIYRMPEDQVAKRGTTVQLECRVK 546
            YTC   N  G     + L V  P    +  +     +G      C  +
Sbjct: 184 TYTCKGENPAGSHSGNLHLNVTSPPIFMQHLQSLTVPQGKDAYFNCVTR 330
>11855
          Length = 1574

 Score = 50.1 bits (118), Expect = 6e-06,   Method: Compositional matrix adjust.
 Identities = 36/95 (37%), Positives = 49/95 (51%), Gaps = 3/95 (3%)
 Frame = +1

Query: 255 SQMVLRGMDLLLECIASGVPTPDIAWYK-KGGDLPSNKAKFE-NFNKALRITNVS-EEDS 311
           S++ L    + L C ASG P P I WY  +   LP N  +F    N  L I ++S  E+ 
Sbjct: 340 SRLELETTTVQLFCRASGYPEPTITWYDGRNNSLPDNSGQFSIAVNGDLIIRDISWSENM 519

Query: 312 GEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNL 346
           G Y C+A N++GS  H  SV+    P  LDEP + 
Sbjct: 520 GVYRCVAENELGS--H--SVQAFLYPTTLDEPDSF 612

 Score = 49.3 bits (116), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 52/203 (25%), Positives = 79/203 (38%), Gaps = 48/203 (23%)
 Frame = +1

Query: 362 GNPKPTVQWMVNG------------------EPLQSAPPNPNREVAGDTIIFRDTQISSR 403
           G+P PT+ W+ +G                  E L S P  P           R +   SR
Sbjct: 1   GSPVPTIHWLKDGVRLTQSTYETVDDESALYEDLASDPGQPR---------LRLSSTKSR 153

Query: 404 AVYQCNTSNEHGYLLANAFV--------SVLDVPPRMLS----------ARNQLIRVILY 445
               C TS + G     A          +++ V  R  S          +R +  RV ++
Sbjct: 154 LYLDCPTSQDEGEYTCVAETPFKRRVQSTIVKVDTRHYSPDVTCMSKRGSRGEPARVYMW 333

Query: 446 NRTRLD---------CPFFGSPIPTLRWFKNGQGSNL--DGGNYHVYENGSLEIKMIR-K 493
             +RL+         C   G P PT+ W+ +G+ ++L  + G + +  NG L I+ I   
Sbjct: 334 TVSRLELETTTVQLFCRASGYPEPTITWY-DGRNNSLPDNSGQFSIAVNGDLIIRDISWS 510

Query: 494 EDQGIYTCVATNILGKAENQVRL 516
           E+ G+Y CVA N LG    Q  L
Sbjct: 511 ENMGVYRCVAENELGSHSVQAFL 579

 Score = 43.9 bits (102), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 51/203 (25%), Positives = 73/203 (35%), Gaps = 45/203 (22%)
 Frame = +1

Query: 272 GVPTPDIAWYKKG------------------GDLPSN----KAKFENFNKALRITNVSEE 309
           G P P I W K G                   DL S+    + +  +    L +   + +
Sbjct: 1   GSPVPTIHWLKDGVRLTQSTYETVDDESALYEDLASDPGQPRLRLSSTKSRLYLDCPTSQ 180

Query: 310 DSGEYFCLASNKMGSIRHTISVRVKAAPYWLD-----------EPKNLIL-------APG 351
           D GEY C+A         +  V+V    Y  D           EP  + +          
Sbjct: 181 DEGEYTCVAETPFKRRVQSTIVKVDTRHYSPDVTCMSKRGSRGEPARVYMWTVSRLELET 360

Query: 352 EDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNR---EVAGDTIIFRDTQISSRAVYQC 408
              +L CRA+G P+PT+ W        S P N  +    V GD II   +   +  VY+C
Sbjct: 361 TTVQLFCRASGYPEPTITWYDGRN--NSLPDNSGQFSIAVNGDLIIRDISWSENMGVYRC 534

Query: 409 NTSNEHGYLLANAFV--SVLDVP 429
              NE G     AF+  + LD P
Sbjct: 535 VAENELGSHSVQAFLYPTTLDEP 603

 Score = 40.4 bits (93), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 45/197 (22%), Positives = 71/197 (36%), Gaps = 45/197 (22%)
 Frame = +1

Query: 456 GSPIPTLRWFKNGQGSNLDGGNYHVYENGS-----------------------LEIKMIR 492
           GSP+PT+ W K+G    L    Y   ++ S                       L +    
Sbjct: 1   GSPVPTIHWLKDG--VRLTQSTYETVDDESALYEDLASDPGQPRLRLSSTKSRLYLDCPT 174

Query: 493 KEDQGIYTCVATNILGKAENQVRLEVK------------------DPTRIYRMPEDQVAK 534
            +D+G YTCVA     +      ++V                   +P R+Y     ++  
Sbjct: 175 SQDEGEYTCVAETPFKRRVQSTIVKVDTRHYSPDVTCMSKRGSRGEPARVYMWTVSRLEL 354

Query: 535 RGTTVQLECRVKHDPSLKLTVSWL---KDDEPLYIGNRMKKEDDSLTIFGVA-ERDQGSY 590
             TTVQL CR    P  + T++W     +  P   G      +  L I  ++   + G Y
Sbjct: 355 ETTTVQLFCRASGYP--EPTITWYDGRNNSLPDNSGQFSIAVNGDLIIRDISWSENMGVY 528

Query: 591 TCMASTELDQDLAKAYL 607
            C+A  EL     +A+L
Sbjct: 529 RCVAENELGSHSVQAFL 579

 Score = 32.7 bits (73), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 42/199 (21%), Positives = 71/199 (35%), Gaps = 41/199 (20%)
 Frame = +1

Query: 67  GNPAPSFHWTRN----------------SRFFNIAKD---PRVSMRRRSGTLVIDFRSGG 107
           G+P P+ HW ++                + + ++A D   PR+ +      L +D  +  
Sbjct: 1   GSPVPTIHWLKDGVRLTQSTYETVDDESALYEDLASDPGQPRLRLSSTKSRLYLDCPTS- 177

Query: 108 RPEEYEGEYQCFARNKFG-------------------TALSNR-IRLQVSKSPLWPKENL 147
              + EGEY C A   F                    T +S R  R + ++  +W    L
Sbjct: 178 ---QDEGEYTCVAETPFKRRVQSTIVKVDTRHYSPDVTCMSKRGSRGEPARVYMWTVSRL 348

Query: 148 DPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQDK-RVSQGHNGDLYFSNVMLQD 206
           +     E   + L C    G P P I W       +  +  + S   NGDL   ++   +
Sbjct: 349 E----LETTTVQLFCR-ASGYPEPTITWYDGRNNSLPDNSGQFSIAVNGDLIIRDISWSE 513

Query: 207 MQTDYSCNARFHF-THTIQ 224
               Y C A     +H++Q
Sbjct: 514 NMGVYRCVAENELGSHSVQ 570
>37675
          Length = 741

 Score = 45.1 bits (105), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 24/95 (25%), Positives = 44/95 (46%)
 Frame = +2

Query: 314 YFCLASNKMGSIRHTISVRVKAAPYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMVN 373
           Y C  S    S++   +++V+  P     P +LI     + ++ C A G PKPT+ W+ N
Sbjct: 5   YSCEDSTDPSSLQ-VHALKVQMPPVVKVSPHSLIYPARLNAKMKCHAEGVPKPTISWLFN 181

Query: 374 GEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQC 408
             P+   P + + E A + ++  +        Y+C
Sbjct: 182 NVPISEDPQHYDLESANELLVVYNAGDQDTGAYKC 286

 Score = 39.3 bits (90), Expect = 0.010,   Method: Compositional matrix adjust.
 Identities = 24/87 (27%), Positives = 42/87 (48%)
 Frame = +2

Query: 38  TQPPTITKQSVKDHIVDPRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSG 97
            Q P + K S    I   R N  ++C A+G P P+  W  N+    I++DP+      + 
Sbjct: 59  VQMPPVVKVSPHSLIYPARLNAKMKCHAEGVPKPTISWLFNN--VPISEDPQHYDLESAN 232

Query: 98  TLVIDFRSGGRPEEYEGEYQCFARNKF 124
            L++ + +G   ++  G Y+C AR + 
Sbjct: 233 ELLVVYNAG---DQDTGAYKCVARIRL 304

 Score = 35.4 bits (80), Expect = 0.16,   Method: Composition-based stats.
 Identities = 17/59 (28%), Positives = 32/59 (54%), Gaps = 2/59 (3%)
 Frame = +2

Query: 266 LECIASGVPTPDIAWYKKGGDLPSNKAKF--ENFNKALRITNVSEEDSGEYFCLASNKM 322
           ++C A GVP P I+W      +  +   +  E+ N+ L + N  ++D+G Y C+A  ++
Sbjct: 128 MKCHAEGVPKPTISWLFNNVPISEDPQHYDLESANELLVVYNAGDQDTGAYKCVARIRL 304

 Score = 33.1 bits (74), Expect = 0.70,   Method: Compositional matrix adjust.
 Identities = 19/86 (22%), Positives = 42/86 (48%), Gaps = 3/86 (3%)
 Frame = +2

Query: 516 LEVKDPTRIYRMPEDQVAKRGTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNR---MKK 572
           L+V+ P  +   P   +       +++C  +  P  K T+SWL ++ P+    +   ++ 
Sbjct: 53  LKVQMPPVVKVSPHSLIYPARLNAKMKCHAEGVP--KPTISWLFNNVPISEDPQHYDLES 226

Query: 573 EDDSLTIFGVAERDQGSYTCMASTEL 598
            ++ L ++   ++D G+Y C+A   L
Sbjct: 227 ANELLVVYNAGDQDTGAYKCVARIRL 304
>17530
          Length = 503

 Score = 43.9 bits (102), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 36/141 (25%), Positives = 60/141 (42%), Gaps = 15/141 (10%)
 Frame = +2

Query: 40  PPTITKQSVKDHIVDPRDNILIECEAKG-NPAPSFHWTRNS-RFFNIAKDPRVSMRRRSG 97
           PP+IT     D + +    +   C + G NP P+  WT+N  +  N  +   V     SG
Sbjct: 62  PPSITSDITGD-VFEEGQRVRFTCSSSGGNPPPTITWTKNGVQLINGVQQIGVGQTSTSG 238

Query: 98  -------TLVIDFRSGGRPEEYEGEYQCFARNK--FGTALSNRIRLQVSKSPLWPKENLD 148
                  ++V+D        +++  Y CF  N+    ++L+  + L V  SP+   E   
Sbjct: 239 GSTRNTVSVVMDH------SDHQANYTCFVYNQVNINSSLTASVVLNVRYSPIITFEPFS 400

Query: 149 PVVVQEGAPLTLQC----NPP 165
           P +V+   P  + C    NPP
Sbjct: 401 PYIVRLDRPANITCQVDANPP 463
>34369
          Length = 300

 Score = 40.8 bits (94), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 28/82 (34%), Positives = 40/82 (48%), Gaps = 1/82 (1%)
 Frame = +3

Query: 639 LAERSVRLTWIPG-DDNNSPITDYVVQFEEDQFQPGVWHDHSRFPGSVNSAVLHLSPYVN 697
           +  R V + W    DDNNSPIT Y VQ  E +    V  +      +    + +L+PY  
Sbjct: 15  IESREVTVYWTTSRDDNNSPITSYTVQVNECENDTTV-RELVTGGSTFQITIPNLTPYTC 191

Query: 698 YQFRVIAVNEVGSSHPSLPSER 719
           Y  +V+A N VG S P   S++
Sbjct: 192 YAIQVLAQNSVGFSDPGPQSDQ 257
>19356
          Length = 451

 Score = 40.4 bits (93), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 27/87 (31%), Positives = 35/87 (40%), Gaps = 4/87 (4%)
 Frame = -2

Query: 518 VKDPTRIYRMPEDQVAKRGTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMKKEDDS- 576
           ++ P  +  MP     + G +V LE RV       L + W K+  PL  G R     D  
Sbjct: 291 IRPPQFVKPMPGLYNLQGGQSVHLETRVIPITDSSLVIEWFKNGRPLNNGCRFNIVFDRG 112

Query: 577 ---LTIFGVAERDQGSYTCMASTELDQ 600
              L I GV   D G Y C A  +  Q
Sbjct: 111 FAILDIIGVISEDTGDYFCFARNKAGQ 31

 Score = 37.4 bits (85), Expect = 0.043,   Method: Compositional matrix adjust.
 Identities = 24/64 (37%), Positives = 31/64 (48%)
 Frame = -2

Query: 73  FHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNRI 132
             W +N R  N     R ++    G  ++D    G   E  G+Y CFARNK G A SN +
Sbjct: 180 IEWFKNGRPLN--NGCRFNIVFDRGFAILDII--GVISEDTGDYFCFARNKAGQAQSNVV 13

Query: 133 RLQV 136
           RL V
Sbjct: 12  RLLV 1

 Score = 37.0 bits (84), Expect = 0.043,   Method: Compositional matrix adjust.
 Identities = 21/56 (37%), Positives = 30/56 (53%), Gaps = 4/56 (7%)
 Frame = -2

Query: 278 IAWYKKGGDLPSNKAKFE-NFNKA---LRITNVSEEDSGEYFCLASNKMGSIRHTI 329
           I W+K G  L +N  +F   F++    L I  V  ED+G+YFC A NK G  +  +
Sbjct: 180 IEWFKNGRPL-NNGCRFNIVFDRGFAILDIIGVISEDTGDYFCFARNKAGQAQSNV 16
>38127
          Length = 860

 Score = 40.0 bits (92), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 37/139 (26%), Positives = 62/139 (44%), Gaps = 16/139 (11%)
 Frame = -1

Query: 473 LDGGNYHV-YENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYRMPEDQ 531
           +DG   ++ + NG+LEI+  R+   G+YTCVA       ++ + ++V        +P D+
Sbjct: 839 VDGKERYIQHNNGTLEIQHPRRNFAGMYTCVAEYEEAGVKSSISVDVPFYAHPKVLPFDK 660

Query: 532 VAK--RGTTVQLECRVKHDPSLKLTVSWLKDDEPLYIG-------------NRMKKEDDS 576
                +  ++ +EC+V   P  K  VSW  D+  +  G             +    E   
Sbjct: 659 SKNLVQDESLVIECKVLGYP--KPVVSWYMDNVEIVDGADSRYSLKPANSYDGASIEGAK 486

Query: 577 LTIFGVAERDQGSYTCMAS 595
           L I  V   D G YTCM++
Sbjct: 485 LVIEEVQFDDAGEYTCMSN 429

 Score = 40.0 bits (92), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 35/129 (27%), Positives = 54/129 (41%), Gaps = 18/129 (13%)
 Frame = -1

Query: 298 NKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRV------KAAPYWLDEPKNLILAPG 351
           N  L I +     +G Y C+A  +   ++ +ISV V      K  P+  D+ KNL+    
Sbjct: 806 NGTLEIQHPRRNFAGMYTCVAEYEEAGVKSSISVDVPFYAHPKVLPF--DKSKNLV---- 645

Query: 352 EDGRLV--CRANGNPKPTVQW------MVNGE----PLQSAPPNPNREVAGDTIIFRDTQ 399
           +D  LV  C+  G PKP V W      +V+G      L+ A       + G  ++  + Q
Sbjct: 644 QDESLVIECKVLGYPKPVVSWYMDNVEIVDGADSRYSLKPANSYDGASIEGAKLVIEEVQ 465

Query: 400 ISSRAVYQC 408
                 Y C
Sbjct: 464 FDDAGEYTC 438

 Score = 33.9 bits (76), Expect = 0.38,   Method: Compositional matrix adjust.
 Identities = 26/113 (23%), Positives = 49/113 (43%), Gaps = 16/113 (14%)
 Frame = -1

Query: 243 TPSFMYPQGT--SSSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDL-----------PS 289
            P + +P+      S+ +++   L++EC   G P P ++WY    ++           P+
Sbjct: 701 VPFYAHPKVLPFDKSKNLVQDESLVIECKVLGYPKPVVSWYMDNVEIVDGADSRYSLKPA 522

Query: 290 NKAKFENFNKA-LRITNVSEEDSGEYFCLA--SNKMGSIRHTISVRVKAAPYW 339
           N     +   A L I  V  +D+GEY C++  ++K      T  + V+    W
Sbjct: 521 NSYDGASIEGAKLVIEEVQFDDAGEYTCMSNYTDKWPQFNSTQVILVRVKTSW 363
>18345
          Length = 461

 Score = 40.0 bits (92), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 24/74 (32%), Positives = 36/74 (48%), Gaps = 2/74 (2%)
 Frame = +1

Query: 266 LECIASGVPTPDIAWYKKGG-DLPSNKAKFENFNKALRITNVSEEDSGEYFCLASNKM-G 323
           L C  +GVP+PD+ WYK+    L + K +  +    L + NV+      Y C A N +  
Sbjct: 172 LVCNVTGVPSPDVTWYKRNTRQLDAQKERVGSTGPVLVMYNVTRHCDDIYECYADNGVPP 351

Query: 324 SIRHTISVRVKAAP 337
           ++   I V V  AP
Sbjct: 352 AVTKAIRVTVDYAP 393

 Score = 29.6 bits (65), Expect = 8.3,   Method: Compositional matrix adjust.
 Identities = 20/71 (28%), Positives = 28/71 (39%), Gaps = 1/71 (1%)
 Frame = +1

Query: 301 LRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLD-EPKNLILAPGEDGRLVCR 359
           L I +V   D+G Y C  + +   I+    V         +  P  + L  G+   LVC 
Sbjct: 4   LLIRHVRLNDTGVYECRINTQPSQIKQVTLVVQVPPVVLSEGSPDRVSLKEGDTATLVCN 183

Query: 360 ANGNPKPTVQW 370
             G P P V W
Sbjct: 184 VTGVPSPDVTW 216
>27666
          Length = 873

 Score = 39.3 bits (90), Expect = 0.010,   Method: Compositional matrix adjust.
 Identities = 39/154 (25%), Positives = 69/154 (44%), Gaps = 5/154 (3%)
 Frame = +1

Query: 189 VSQGHNGDLYFSNVMLQDMQTD---YSCNARFHFTHTIQQKNPFTLKVLTTRGVAERTPS 245
           V  G    L F+ V+ +  Q D   Y C  +      IQ +N  + +V     +  + P 
Sbjct: 358 VQHGPPDRLTFTLVIRRLRQQDAGTYVCQVK------IQNENILS-QVQKIGTLTVQVPP 516

Query: 246 FMYPQGTSSSQMVLRGMDLLLECIASGVPTPDIAWYK-KGGDLPSNKAKFENFNKALRIT 304
            + P  T++   + +  +  L C ++G+P P+I W +  G  LP+  ++F    + L + 
Sbjct: 517 KIRPGETTTLVEIDQNQNSSLVCSSTGIPAPNITWTRLDGRALPTGYSQFR--GRELPLN 690

Query: 305 NVSEEDSGEYFCLASNKMG-SIRHTISVRVKAAP 337
             + +  G Y C+A+N +     H   VRV  AP
Sbjct: 691 GATVDHMGVYRCVANNNIKPPDDHLCEVRVFHAP 792

 Score = 31.2 bits (69), Expect = 2.5,   Method: Compositional matrix adjust.
 Identities = 26/119 (21%), Positives = 49/119 (41%), Gaps = 7/119 (5%)
 Frame = +1

Query: 301 LRITNVSEEDSGEYFCLAS----NKMGSIRHTISVRVKAAPYWL-DEPKNLI-LAPGEDG 354
           L I  + ++D+G Y C       N +  ++   ++ V+  P     E   L+ +   ++ 
Sbjct: 394 LVIRRLRQQDAGTYVCQVKIQNENILSQVQKIGTLTVQVPPKIRPGETTTLVEIDQNQNS 573

Query: 355 RLVCRANGNPKPTVQWM-VNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSN 412
            LVC + G P P + W  ++G  L    P    +  G  +      +    VY+C  +N
Sbjct: 574 SLVCSSTGIPAPNITWTRLDGRAL----PTGYSQFRGRELPLNGATVDHMGVYRCVANN 738

 Score = 29.6 bits (65), Expect = 7.7,   Method: Compositional matrix adjust.
 Identities = 27/122 (22%), Positives = 46/122 (37%), Gaps = 8/122 (6%)
 Frame = +1

Query: 392 TIIFRDTQISSRAVYQCNTSNEHGYLLANA---FVSVLDVPPRMLSARNQLIRVILYNR- 447
           T++ R  +      Y C    ++  +L+         + VPP++       +  I  N+ 
Sbjct: 391 TLVIRRLRQQDAGTYVCQVKIQNENILSQVQKIGTLTVQVPPKIRPGETTTLVEIDQNQN 570

Query: 448 TRLDCPFFGSPIPTLRWFKNGQGSNLDG----GNYHVYENGSLEIKMIRKEDQGIYTCVA 503
           + L C   G P P + W      + LDG      Y  +    L +     +  G+Y CVA
Sbjct: 571 SSLVCSSTGIPAPNITW------TRLDGRALPTGYSQFRGRELPLNGATVDHMGVYRCVA 732

Query: 504 TN 505
            N
Sbjct: 733 NN 738
>25766
          Length = 469

 Score = 30.8 bits (68), Expect(2) = 0.010,   Method: Composition-based stats.
 Identities = 16/42 (38%), Positives = 22/42 (52%)
 Frame = +3

Query: 479 HVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKD 520
           H   NG L +  I+KED+G Y C A++  G   +   L V D
Sbjct: 309 HQIRNGILTLYNIQKEDEGRYICTASSENGVDRDYSNLRVSD 434

 Score = 27.7 bits (60), Expect(2) = 0.010,   Method: Compositional matrix adjust.
 Identities = 13/62 (20%), Positives = 29/62 (46%)
 Frame = +1

Query: 406 YQCNTSNEHGYLLANAFVSVLDVPPRMLSARNQLIRVILYNRTRLDCPFFGSPIPTLRWF 465
           Y+C  ++  G + +  F ++    P ++S + +     + +  +  C   G P+P +RW 
Sbjct: 106 YRCVITSSEG-ITSEGFATLRISSPPVVSVKQRNENRQVGSSVKFHCDVSGDPVPQVRWE 282

Query: 466 KN 467
           K 
Sbjct: 283 KK 288

 Score = 34.3 bits (77), Expect = 0.32,   Method: Compositional matrix adjust.
 Identities = 18/80 (22%), Positives = 37/80 (46%), Gaps = 1/80 (1%)
 Frame = +1

Query: 292 AKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTIS-VRVKAAPYWLDEPKNLILAP 350
            +   ++  L+I  V+  D+G Y C+ ++  G      + +R+ + P    + +N     
Sbjct: 40  GRVREYDGILQIPRVTAADAGRYRCVITSSEGITSEGFATLRISSPPVVSVKQRNENRQV 219

Query: 351 GEDGRLVCRANGNPKPTVQW 370
           G   +  C  +G+P P V+W
Sbjct: 220 GSSVKFHCDVSGDPVPQVRW 279
>32888
          Length = 418

 Score = 30.0 bits (66), Expect(2) = 0.013,   Method: Compositional matrix adjust.
 Identities = 17/43 (39%), Positives = 21/43 (48%), Gaps = 2/43 (4%)
 Frame = -3

Query: 449 RLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGS--LEIK 489
           RLDC   G P P + W+KNG          H+  NG   +EIK
Sbjct: 221 RLDCRAKGKPSPKVTWYKNG----------HIITNGDDRVEIK 123

 Score = 27.7 bits (60), Expect(2) = 0.013,   Method: Composition-based stats.
 Identities = 11/26 (42%), Positives = 17/26 (65%)
 Frame = -2

Query: 486 LEIKMIRKEDQGIYTCVATNILGKAE 511
           L IK +  ED+G YTC+ +N  G+ +
Sbjct: 114 LTIKSLGAEDKGNYTCIVSNTEGQID 37

 Score = 31.6 bits (70), Expect = 1.9,   Method: Compositional matrix adjust.
 Identities = 11/24 (45%), Positives = 15/24 (62%)
 Frame = -3

Query: 261 GMDLLLECIASGVPTPDIAWYKKG 284
           G  + L+C A G P+P + WYK G
Sbjct: 233 GQTVRLDCRAKGKPSPKVTWYKNG 162

 Score = 31.2 bits (69), Expect = 2.9,   Method: Compositional matrix adjust.
 Identities = 13/24 (54%), Positives = 14/24 (58%)
 Frame = -3

Query: 351 GEDGRLVCRANGNPKPTVQWMVNG 374
           G+  RL CRA G P P V W  NG
Sbjct: 233 GQTVRLDCRAKGKPSPKVTWYKNG 162
>17679
          Length = 509

 Score = 37.7 bits (86), Expect = 0.027,   Method: Compositional matrix adjust.
 Identities = 17/37 (45%), Positives = 22/37 (59%)
 Frame = +3

Query: 826 SAPRRFRVRQPNLETINLEWDHPEHPNGILIGYILRY 862
           +APR  R R  +  TI + W  PE PNGI+ GY + Y
Sbjct: 132 TAPRNVRARAASSTTIVVSWSEPEIPNGIIQGYRVFY 242
>07945
          Length = 2023

 Score = 37.4 bits (85), Expect = 0.040,   Method: Compositional matrix adjust.
 Identities = 39/131 (29%), Positives = 54/131 (41%), Gaps = 5/131 (3%)
 Frame = -3

Query: 593  MASTELDQDLAKA----YLTVLADQATPTNRLAALPKGRPDRPRDLELTDLAERSVRLTW 648
            M +T+  +D  +     Y   + D A  +    A P+G+P  P     TD+   S+ L+W
Sbjct: 1823 MGTTQSHRDPGRGRGDLYGAEVTDHALNSKDKPAPPRGKPCPPSQPVATDITHNSLTLSW 1644

Query: 649  IPGDDNNS-PITDYVVQFEEDQFQPGVWHDHSRFPGSVNSAVLHLSPYVNYQFRVIAVNE 707
             P   N+S  I  Y V+        G W   +         V  LSP   Y FRV A N 
Sbjct: 1643 QPPRRNSSDTIYAYTVEKTXPSDXKG-WTIVTTSCQGNQYQVKKLSPSSQYVFRVRAENI 1467

Query: 708  VGSSHPSLPSE 718
             G S  S PS+
Sbjct: 1466 HGVSKGSRPSD 1434
>12764
          Length = 1055

 Score = 36.2 bits (82), Expect = 0.090,   Method: Compositional matrix adjust.
 Identities = 26/90 (28%), Positives = 39/90 (43%), Gaps = 3/90 (3%)
 Frame = +1

Query: 245 SFMYPQGTS---SSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSNKAKFENFNKAL 301
           S  YP   S    +Q    G++L L CI  G P P +  +++ G+           N  L
Sbjct: 214 SVQYPVTVSVTPDTQQREEGLNLDLTCITQGNPLPFLVEWRQEGE----NTTLATGN-TL 378

Query: 302 RITNVSEEDSGEYFCLASNKMGSIRHTISV 331
            +TN+S  D+G Y C   N +  +  T S 
Sbjct: 379 TLTNLSLSDTGTYTCTGYNTVVGVNKTNSA 468

 Score = 33.1 bits (74), Expect = 0.73,   Method: Compositional matrix adjust.
 Identities = 20/80 (25%), Positives = 37/80 (46%)
 Frame = +1

Query: 515 RLEVKDPTRIYRMPEDQVAKRGTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMKKED 574
           ++ V+ P  +   P+ Q  + G  + L C  + +P L   V W ++ E     N      
Sbjct: 208 QISVQYPVTVSVTPDTQQREEGLNLDLTCITQGNP-LPFLVEWRQEGE-----NTTLATG 369

Query: 575 DSLTIFGVAERDQGSYTCMA 594
           ++LT+  ++  D G+YTC  
Sbjct: 370 NTLTLTNLSLSDTGTYTCTG 429
>20244
          Length = 452

 Score = 28.1 bits (61), Expect(2) = 0.091,   Method: Composition-based stats.
 Identities = 13/34 (38%), Positives = 18/34 (52%)
 Frame = -1

Query: 259 LRGMDLLLECIASGVPTPDIAWYKKGGDLPSNKA 292
           L G   +L C A+G P P+I W  K   + + KA
Sbjct: 404 LNGGIAVLRCFATGNPAPNITWSLKNVVIDTTKA 303

 Score = 26.9 bits (58), Expect(2) = 0.091,   Method: Compositional matrix adjust.
 Identities = 22/62 (35%), Positives = 28/62 (45%), Gaps = 5/62 (8%)
 Frame = -2

Query: 314 YFCL-ASNKMGS-IRHTISVRVKA---APYWLDEPKNLILAPGEDGRLVCRANGNPKPTV 368
           Y CL ASN +G  +R  + ++V     A   LD P+N    PG      C   G P P V
Sbjct: 241 YLCLLASNGLGEPVRREVELQVTVNAEAVIGLD-PQN-SYTPGSTIAFNCSVQGYPTPNV 68

Query: 369 QW 370
            W
Sbjct: 67  TW 62
>29932
          Length = 748

 Score = 34.3 bits (77), Expect = 0.28,   Method: Compositional matrix adjust.
 Identities = 15/47 (31%), Positives = 26/47 (55%)
 Frame = +3

Query: 299 KALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKN 345
           + LR   ++  D+G Y C ASNK G+   T  V V+   ++  +P++
Sbjct: 246 QILRFVAITPADAGGYSCTASNKYGTNSKTAQVVVRPPTFYTQQPQS 386
>10921
          Length = 525

 Score = 32.7 bits (73), Expect = 0.93,   Method: Compositional matrix adjust.
 Identities = 33/124 (26%), Positives = 57/124 (45%), Gaps = 12/124 (9%)
 Frame = -2

Query: 393 IIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVLDVPPRMLSARNQLIRVILYNRTRLDC 452
           +I  +  ++ +A Y C   +E  +     F++V+D+P + L+ + +       + + L C
Sbjct: 416 LIIVNVTLNDQAEYTCKAGSESYF----GFLTVIDLP-QNLTVQWETTPTP-SSTSNLSC 255

Query: 453 -PFFGSPIPTLRWFKNGQGSNLDGGNYHVYEN----------GSLEIKMIRKEDQG-IYT 500
                 P P L WFKNG    LDG   H Y             +L ++  R ED+G ++T
Sbjct: 254 VASRAHPPPPLSWFKNGV--RLDGSRAHYYATTDHSGYGDAVSTLPLET-RGEDEGSVFT 84

Query: 501 CVAT 504
           C A+
Sbjct: 83  CEAS 72
>29881
          Length = 416

 Score = 32.3 bits (72), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 17/54 (31%), Positives = 27/54 (50%), Gaps = 4/54 (7%)
 Frame = -3

Query: 276 PDIAWYKKGGDL----PSNKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSI 325
            D+  ++K GD+    P  +    N+   L ++NV E D+G+Y C A N  G  
Sbjct: 366 ADVTMWRKDGDMFTQGPRKRMLVNNY---LMVSNVVETDAGQYTCAARNSEGCF 214
>11732
          Length = 640

 Score = 31.6 bits (70), Expect = 2.3,   Method: Compositional matrix adjust.
 Identities = 22/88 (25%), Positives = 37/88 (42%)
 Frame = +2

Query: 301 LRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNLILAPGEDGRLVCRA 360
           L  +++S +D+G Y C +++ M  +   I++ V   P          +  G     VC A
Sbjct: 50  LSFSDLSMDDAGLYQCKSTSGMEQVIRNITLFVVLEPQIKRNMSTFTMLDGI-AEAVCVA 226

Query: 361 NGNPKPTVQWMVNGEPLQSAPPNPNREV 388
            G+P PT  +  N   L       + EV
Sbjct: 227 EGDPAPTFLFRGNHVELSDDSEGHDIEV 310
>07940
          Length = 1336

 Score = 31.2 bits (69), Expect = 2.5,   Method: Compositional matrix adjust.
 Identities = 14/38 (36%), Positives = 21/38 (55%)
 Frame = -3

Query: 577  LTIFGVAERDQGSYTCMASTELDQDLAKAYLTVLADQA 614
            L I  +   D G YTC+ S  +  +   A+LTV+ D+A
Sbjct: 1331 LIISNITVEDAGWYTCVVSNAIGVEYGSAWLTVVLDRA 1218
>05091
          Length = 1556

 Score = 30.0 bits (66), Expect = 6.8,   Method: Compositional matrix adjust.
 Identities = 32/85 (37%), Positives = 43/85 (50%), Gaps = 5/85 (5%)
 Frame = -1

Query: 1137 GKYPVREKKDVPLG--PEDPKEEDGSFDYSDEDNKPL-QGSQTSLDGTIKQQESDDSLV- 1192
            G YPV ++K+V  G  PE   ++ G  + S  D   L +  Q +LD        DDS   
Sbjct: 1103 GAYPV-DRKEVAAGLDPEKEMKDSGFNELSRADYDFLPEKKQPNLDFDEIPMGDDDSFAS 927

Query: 1193 -DYGEGGEGQFNEDGSFIGQYTVKK 1216
             +YG+  +  FNEDGSFIG Y   K
Sbjct: 926  DEYGDE-DACFNEDGSFIGVYAKGK 855
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|161168996|ref|NP_082213.2| CASK interacting protein 1
[Mus musculus]
         (1431 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

06253                                                                  97   4e-20
02114                                                                  87   4e-17
34970                                                                  81   3e-15
11295                                                                  77   5e-14
09292                                                                  75   2e-13
19166                                                                  72   2e-12
05924                                                                  69   1e-11
13462                                                                  67   4e-11
14005                                                                  65   2e-10
20036                                                                  65   3e-10
21532                                                                  65   3e-10
25470                                                                  64   3e-10
28691                                                                  61   3e-09
00540                                                                  61   4e-09
20792                                                                  53   3e-08
08473                                                                  56   1e-07
09180                                                                  55   1e-07
02055                                                                  54   4e-07
15359                                                                  54   5e-07
28113                                                                  54   5e-07
28494                                                                  52   1e-06
15772                                                                  49   1e-05
25464                                                                  49   1e-05
20884                                                                  40   1e-05
12417                                                                  48   3e-05
16561                                                                  47   5e-05
30463                                                                  47   8e-05
38834                                                                  46   9e-05
33144                                                                  45   2e-04
17893                                                                  44   6e-04
27067                                                                  42   0.002
14754                                                                  41   0.003
30978                                                                  41   0.004
13622                                                                  40   0.005
02351                                                                  40   0.007
20121                                                                  40   0.008
30217                                                                  39   0.022
33484                                                                  38   0.029
22305                                                                  38   0.036
07218                                                                  37   0.049
27252                                                                  37   0.067
05396                                                                  36   0.14 
03590                                                                  35   0.15 
13900                                                                  33   0.57 
21751                                                                  33   0.70 
28491                                                                  33   0.74 
28539                                                                  33   0.93 
36917                                                                  32   1.4  
27108                                                                  30   5.2  
36879                                                                  30   5.4  
18050                                                                  30   6.2  
18216                                                                  30   6.6  
>06253
          Length = 1049

 Score = 97.1 bits (240), Expect = 4e-20,   Method: Compositional matrix adjust.
 Identities = 75/220 (34%), Positives = 112/220 (50%), Gaps = 14/220 (6%)
 Frame = -1

Query: 53   LHHAALNGNTELISLLLEAQAAVDIKDNKGMRPLHYAAWQGRKEPMKLVLKAGSAVNVPS 112
            LH AA  G  +++  LLE  A V  +D+ G+ PLH A   G  E ++L+L+ G+  N   
Sbjct: 1034 LHFAAGFGRKDVVEHLLENGANVHARDDGGLIPLHNACSFGHAEVVQLLLRHGADPNARD 855

Query: 113  DEGHIPLHLAAQHGHYDVSEMLLQHQSNPCMVDNSGKTPLDLA---------CEFGRVGV 163
            +  + PLH AA  G  DV  +LLQ  ++P + +  GKT LDLA          E+ +  +
Sbjct: 854  NWNYTPLHEAAIKGKIDVCIVLLQQCADPNIRNTDGKTALDLADASAKAVLTGEYKKDEL 675

Query: 164  VQLLLSSN--MCAALLEPRPGDTTDPNG--TSPLHLAAKNGHIDIIRLLLQAGIDINRQT 219
            ++   S N     ALL P   +    +G  ++PLHLAA      I++LLLQ G D++ + 
Sbjct: 674  LEAARSGNEEQMMALLTPLNVNCHASDGRKSTPLHLAAGYNRTRIVQLLLQHGADVHAKD 495

Query: 220  KSGTA-LHEAALCGKTEVVRLLLDSGINAQVRNTYSQTAL 258
            K G   LH A   G  EV  +LL +G +    + +  T L
Sbjct: 494  KGGLVPLHNACSYGHFEVTEMLLXAGASVNAVDLWQFTPL 375

 Score = 85.5 bits (210), Expect = 1e-16,   Method: Compositional matrix adjust.
 Identities = 73/242 (30%), Positives = 107/242 (44%), Gaps = 22/242 (9%)
 Frame = -1

Query: 41  NVNFQDPDGFSALHHAALNGNTELISLLLEAQAAVDIKDNKGMRPLHYAAWQGRKEPMKL 100
           NV+ +D  G   LH+A   G+ E++ LLL   A  + +DN    PLH AA +G+ +   +
Sbjct: 971 NVHARDDGGLIPLHNACSFGHAEVVQLLLRHGADPNARDNWNYTPLHEAAIKGKIDVCIV 792

Query: 101 VLKAGSAVNVPSDEGHIPLHL------AAQHGHYDVSEMLLQHQS--------------- 139
           +L+  +  N+ + +G   L L      A   G Y   E+L   +S               
Sbjct: 791 LLQQCADPNIRNTDGKTALDLADASAKAVLTGEYKKDELLEAARSGNEEQMMALLTPLNV 612

Query: 140 NPCMVDNSGKTPLDLACEFGRVGVVQLLLSSNMCAALLEPRPGDTTDPNGTSPLHLAAKN 199
           N    D    TPL LA  + R  +VQLLL                 D  G  PLH A   
Sbjct: 611 NCHASDGRKSTPLHLAAGYNRTRIVQLLLQHGA--------DVHAKDKGGLVPLHNACSY 456

Query: 200 GHIDIIRLLLQAGIDINR-QTKSGTALHEAALCGKTEVVRLLLDSGINAQVRNTYSQTAL 258
           GH ++  +LL AG  +N       T LHEAA   + EV  LLL  G +  + N +S++ +
Sbjct: 455 GHFEVTEMLLXAGASVNAVDLWQFTPLHEAASKSRVEVCSLLLAHGADPNLVNCHSKSII 276

Query: 259 DI 260
           D+
Sbjct: 275 DV 270

 Score = 70.1 bits (170), Expect = 6e-12,   Method: Compositional matrix adjust.
 Identities = 66/221 (29%), Positives = 103/221 (46%), Gaps = 21/221 (9%)
 Frame = -1

Query: 22  LLQRPRPG-KAKLLGSTKKINVNFQDPDGFSA--LHHAALNGNTELISLLLEAQAAVDIK 78
           LL+  R G + +++     +NVN    DG  +  LH AA    T ++ LLL+  A V  K
Sbjct: 677 LLEAARSGNEEQMMALLTPLNVNCHASDGRKSTPLHLAAGYNRTRIVQLLLQHGADVHAK 498

Query: 79  DNKGMRPLHYAAWQGRKEPMKLVLKAGSAVNVPSDEGHIPLHLAAQHGHYDVSEMLLQHQ 138
           D  G+ PLH A   G  E  +++L AG++VN        PLH AA     +V  +LL H 
Sbjct: 497 DKGGLVPLHNACSYGHFEVTEMLLXAGASVNAVDLWQFTPLHEAASKSRVEVCSLLLAHG 318

Query: 139 SNPCMVDNSGKTPLDLA--------CEFGRVGVVQLLLSSNMCAALLEPRPGDTTD---- 186
           ++P +V+   K+ +D+A         +F   G    LL     A L   +     D    
Sbjct: 317 ADPNLVNCHSKSIIDVAPTRELQERIQFEYKG--HSLLEGARQADLARVKKYLAVDIVNF 144

Query: 187 ---PNGTSPLHLAAKN---GHIDIIRLLLQAGIDINRQTKS 221
               NG + LH AA +       ++ LL++ G ++N +TK+
Sbjct: 143 KHPYNGDTALHCAAASPFPKRKQVVELLVRKGGNLNEKTKT 21

 Score = 67.8 bits (164), Expect = 3e-11,   Method: Compositional matrix adjust.
 Identities = 46/112 (41%), Positives = 62/112 (55%), Gaps = 1/112 (0%)
 Frame = -1

Query: 150  TPLDLACEFGRVGVVQLLLSSNMCAALLEPRPGDTTDPNGTSPLHLAAKNGHIDIIRLLL 209
            TPL  A  FGR  VV+ LL +    A +  R     D  G  PLH A   GH ++++LLL
Sbjct: 1040 TPLHFAAGFGRKDVVEHLLEN---GANVHAR-----DDGGLIPLHNACSFGHAEVVQLLL 885

Query: 210  QAGIDIN-RQTKSGTALHEAALCGKTEVVRLLLDSGINAQVRNTYSQTALDI 260
            + G D N R   + T LHEAA+ GK +V  +LL    +  +RNT  +TALD+
Sbjct: 884  RHGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQQCADPNIRNTDGKTALDL 729
>02114
          Length = 1072

 Score = 87.4 bits (215), Expect = 4e-17,   Method: Compositional matrix adjust.
 Identities = 62/235 (26%), Positives = 119/235 (50%), Gaps = 6/235 (2%)
 Frame = +1

Query: 36  STKKINVNFQDPDGFSALHHAALNGNTELISLLLEAQAAVDIKDNKGMRPLHYAAWQGRK 95
           S   ++++ +D  G + LH A  +G++  +  LL     V+  D      +H +++ GR 
Sbjct: 262 SNNGVSMSAKDTRGSTPLHLACAHGHSFCVQTLLRCGVDVNSVDKTSWTSVHVSSYHGRL 441

Query: 96  EPMKLVLKAGSAVNVPSDEGHIPLHLAAQHGHYDVSEMLLQHQSNPCMV----DNSGKTP 151
             +++++K G+  +     G+ P HLAA  GH    + L+  +  P       ++ G+TP
Sbjct: 442 GCLQMLIKWGARYDDIDTNGNTPAHLAAMEGHLPCLKFLVSSEGCPEHTLGARNDHGETP 621

Query: 152 LDLACEFGRVGVVQLLLSSNMCAALLEPRPGDTTDPNGTSPLHLAAKNGHIDIIRLLLQA 211
            DLA +F +  +++ +   ++   +  P   +    N   P H+AA NG +D +R+L++ 
Sbjct: 622 RDLAQQFYKENILEYI--DHVQHEMDHPEQAE----NLAFPAHMAAYNGELDHLRILVEN 783

Query: 212 G-IDIN-RQTKSGTALHEAALCGKTEVVRLLLDSGINAQVRNTYSQTALDIVHQF 264
           G ++IN R  K  T  H AA  G   +++ L++ G + ++ N   +TA DI  +F
Sbjct: 784 GVVNINERDDKGNTLAHRAAGQGHLNILQWLVEMGADVEISNGAGETARDIARRF 948

 Score = 47.8 bits (112), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 45/176 (25%), Positives = 75/176 (42%), Gaps = 7/176 (3%)
 Frame = +1

Query: 111 PSDEGHIPLHLAAQHGHYDVSEMLLQHQSNPCMVDNSGKTPLDLACEFGRVGVVQLLLSS 170
           P+  G  P H+AA  G     + L  +  +    D  G TPL LAC  G    VQ LL  
Sbjct: 190 PTPRGWTPAHIAAIRGQEGCIQALSNNGVSMSAKDTRGSTPLHLACAHGHSFCVQTLLRC 369

Query: 171 NMCAALLEPRPGDTTDPNGTSPLHLAAKNGHIDIIRLLLQAGI---DINRQTKSGTALHE 227
            +          ++ D    + +H+++ +G +  +++L++ G    DI+  T   T  H 
Sbjct: 370 GV--------DVNSVDKTSWTSVHVSSYHGRLGCLQMLIKWGARYDDID--TNGNTPAHL 519

Query: 228 AALCGKTEVVRLLLDS-GI---NAQVRNTYSQTALDIVHQFTTSQASKEIKQLLRE 279
           AA+ G    ++ L+ S G        RN + +T  D+  QF      + I  +  E
Sbjct: 520 AAMEGHLPCLKFLVSSEGCPEHTLGARNDHGETPRDLAQQFYKENILEYIDHVQHE 687

 Score = 43.5 bits (101), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 23/84 (27%), Positives = 48/84 (57%), Gaps = 1/84 (1%)
 Frame = +1

Query: 85  PLHYAAWQGRKEPMKLVLKAGSA-VNVPSDEGHIPLHLAAQHGHYDVSEMLLQHQSNPCM 143
           P H AA+ G  + ++++++ G   +N   D+G+   H AA  GH ++ + L++  ++  +
Sbjct: 724 PAHMAAYNGELDHLRILVENGVVNINERDDKGNTLAHRAAGQGHLNILQWLVEMGADVEI 903

Query: 144 VDNSGKTPLDLACEFGRVGVVQLL 167
            + +G+T  D+A  F  +  V+LL
Sbjct: 904 SNGAGETARDIARRFAHLACVKLL 975
>34970
          Length = 505

 Score = 81.3 bits (199), Expect = 3e-15,   Method: Compositional matrix adjust.
 Identities = 36/62 (58%), Positives = 44/62 (70%)
 Frame = -1

Query: 551 AVWLSMIGLAQYYKVLVDNGYENIDFITDITWEDLQEIGITKLGHQKKLMLAVRKLAELQ 610
           A WL   GL  Y   L   GY+NID++TDITWEDL+EIGI KLGHQKK+MLAV ++  + 
Sbjct: 505 ATWL---GLGMYLDTLASQGYDNIDYVTDITWEDLEEIGIKKLGHQKKIMLAVDRMKRIT 335

Query: 611 KA 612
            A
Sbjct: 334 SA 329

 Score = 37.7 bits (86), Expect = 0.032,   Method: Compositional matrix adjust.
 Identities = 20/55 (36%), Positives = 29/55 (52%), Gaps = 1/55 (1%)
 Frame = -1

Query: 484 WLATFQLQLYAPNFTSAGYD-LPTISRMTPEDLTAIGVTKPGHRKKITAEISGLN 537
           WL    L +Y     S GYD +  ++ +T EDL  IG+ K GH+KKI   +  + 
Sbjct: 499 WLG---LGMYLDTLASQGYDNIDYVTDITWEDLEEIGIKKLGHQKKIMLAVDRMK 344
>11295
          Length = 1179

 Score = 77.0 bits (188), Expect = 5e-14,   Method: Composition-based stats.
 Identities = 71/250 (28%), Positives = 107/250 (42%), Gaps = 27/250 (10%)
 Frame = +1

Query: 40  INVNFQDPDGFSALHHAALNGNTELISLLLEAQAAVDIKDNKGMRPLHYAAWQGRKEPMK 99
           I VN    D  +ALH A    + E+ SLLL+  A     D  G  PLH A W G +   +
Sbjct: 148 IAVNATSNDHVTALHIACCLDDREMASLLLKYGAYAMALDVIGHTPLHVACWCGSEGVTR 327

Query: 100 LVL-KAGSAVNVPSDEGHIPLHLAAQHGHYDVSEMLLQHQSNPCMVDNSGKTPLDLACEF 158
           L+L ++   VN    +G  PL LA++ G + +   LL H ++  + D +  TP   A  +
Sbjct: 328 LLLDRSDVDVNALDHDGKXPLRLASECGFHYIIRQLLYHNADHTIRDAAEFTPFHCAIRY 507

Query: 159 GRVGVVQLLL------------------------SSNMCAALLEPRPG-DTTDPNGTSPL 193
            RV  V+  L                           M + L++     +  D    +PL
Sbjct: 508 CRVLAVKTFLVWFPDLIHSFYNDLSPTFMACLQCDKEMLSLLIKFGASVNCADHYHYTPL 687

Query: 194 HLAAKNGHIDIIRLLLQAGIDINRQTKSG-TALHEAALCGKTEVVRLLLDSGINAQVRNT 252
           H  ++ GH+ +++LLLQ   + N     G T L+ A+  G   +V +LL SG        
Sbjct: 688 HYISRRGHLTMLQLLLQGKAEPNVVDDEGITPLYIASCEGHVTIVNILLQSGA-----KI 852

Query: 253 YSQTALDIVH 262
           Y   A D VH
Sbjct: 853 YMPCARDPVH 882

 Score = 70.1 bits (170), Expect = 6e-12,   Method: Composition-based stats.
 Identities = 58/206 (28%), Positives = 84/206 (40%), Gaps = 33/206 (16%)
 Frame = +1

Query: 29  GKAKLLGSTKKINVNFQDPDGFSALHHAALNGNTELISLLLEAQAAVDIKDNKGMRPLHY 88
           G  +LL     ++VN  D DG   L  A+  G   +I  LL   A   I+D     P H 
Sbjct: 316 GVTRLLLDRSDVDVNALDHDGKXPLRLASECGFHYIIRQLLYHNADHTIRDAAEFTPFHC 495

Query: 89  A-------------AW--------------------QGRKEPMKLVLKAGSAVNVPSDEG 115
           A              W                    Q  KE + L++K G++VN      
Sbjct: 496 AIRYCRVLAVKTFLVWFPDLIHSFYNDLSPTFMACLQCDKEMLSLLIKFGASVNCADHYH 675

Query: 116 HIPLHLAAQHGHYDVSEMLLQHQSNPCMVDNSGKTPLDLACEFGRVGVVQLLLSSNMCAA 175
           + PLH  ++ GH  + ++LLQ ++ P +VD+ G TPL +A   G V +V +LL S     
Sbjct: 676 YTPLHYISRRGHLTMLQLLLQGKAEPNVVDDEGITPLYIASCEGHVTIVNILLQSGAKIY 855

Query: 176 LLEPRPGDTTDPNGTSPLHLAAKNGH 201
           +          P    P+H A K GH
Sbjct: 856 M----------PCARDPVHAACKAGH 903

 Score = 67.8 bits (164), Expect = 3e-11,   Method: Composition-based stats.
 Identities = 78/297 (26%), Positives = 124/297 (41%), Gaps = 12/297 (4%)
 Frame = +1

Query: 42  VNFQDPDGFSALHHAALNGNTELISLLLEA----QAAVDIKDNKGMRPLHYAAWQGRKEP 97
           + + D  G SALHHA +  NTE+  LLL+       AV+   N  +  LH A     +E 
Sbjct: 43  IYWTDHRGLSALHHACIGRNTEVAELLLDGWNGDGIAVNATSNDHVTALHIACCLDDREM 222

Query: 98  MKLVLKAGSAVNVPSDEGHIPLHLAAQHGHYDVSEMLLQHQS-NPCMVDNSGKTPLDLAC 156
             L+LK G+        GH PLH+A   G   V+ +LL     +   +D+ GK PL LA 
Sbjct: 223 ASLLLKYGAYAMALDVIGHTPLHVACWCGSEGVTRLLLDRSDVDVNALDHDGKXPLRLAS 402

Query: 157 EFGRVGVVQLLLSSNMCAALLEPRPGDTT--DPNGTSPLHLAAKNGHIDIIRLLLQAGID 214
           E G   +++ LL  N           D T  D    +P H A +   +  ++  L    D
Sbjct: 403 ECGFHYIIRQLLYHN----------ADHTIRDAAEFTPFHCAIRYCRVLAVKTFLVWFPD 552

Query: 215 -INRQTKSGTALHEAALCGKTEVVRLLLDSGINAQVRNTYSQTALDIVHQFTTSQASKEI 273
            I+      +    A L    E++ LL+  G +    + Y  T L     + + +    +
Sbjct: 553 LIHSFYNDLSPTFMACLQCDKEMLSLLIKFGASVNCADHYHYTPL----HYISRRGHLTM 720

Query: 274 KQLLREASAALQVRATKDYCNNYDLTSLNVKAGD----IITVLEQHPDGRWKGCIHD 326
            QLL      LQ +A  +  ++  +T L + + +    I+ +L Q     +  C  D
Sbjct: 721 LQLL------LQGKAEPNVVDDEGITPLYIASCEGHVTIVNILLQSGAKIYMPCARD 873
>09292
          Length = 1486

 Score = 75.1 bits (183), Expect = 2e-13,   Method: Compositional matrix adjust.
 Identities = 66/249 (26%), Positives = 109/249 (43%), Gaps = 22/249 (8%)
 Frame = -2

Query: 45   QDPDGFSALHHAALNGNTELISLLLEAQAAVDIKDNKGMRPLHYAAWQGRKEPMKLVLKA 104
            Q P  F ALH A    + E +   L+    VD +D+     LH   + G  +   ++LK 
Sbjct: 1473 QQPASFCALHCAXQLQDVETLLAYLDIGMHVDTRDSHHETALHAVCYVGSVKMASVLLKH 1294

Query: 105  GSAVNVPSDEGHIPLHLAAQHGHYDVSEMLLQHQSNPCMVDNSGKTPLDLACEFGRVGVV 164
             + VN  ++    PLH+ A  GH  + E L++H ++    D    TP+  AC      +V
Sbjct: 1293 XADVNARNNVDRTPLHIXAIEGHLGLVEELVRHGADFNAEDKDHLTPVFNACVKNDTDIV 1114

Query: 165  QLLLS--------------------SNMCAALLEPRPGDTTDPNGTSPLHLAAKNGHIDI 204
            + LL                     S +   LL       + P   SPLH+A +NG+I++
Sbjct: 1113 RYLLESGARANTTARPIFHAVKYGYSEIVQLLLVHGAAVNSLPGTKSPLHIACRNGNIEM 934

Query: 205  IRLLLQAGIDINRQTKSG-TALHEAALC-GKTEVVRLLLDSGINAQVRNTYSQTALDIVH 262
             R ++ AG ++N   K G T LH +       ++VRLL+  G N +  N   Q  L +  
Sbjct: 933  ARTVIIAGANVNAVDKDGNTPLHISVRAPSSAQLVRLLIRFGANVKWGNDNQQIPLHLAC 754

Query: 263  QFTTSQASK 271
             ++  + ++
Sbjct: 753  LYSNLETAR 727

 Score = 68.2 bits (165), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 53/176 (30%), Positives = 82/176 (46%), Gaps = 4/176 (2%)
 Frame = -2

Query: 41  NVNFQDPDGFSALHHAALN-GNTELISLLLEAQAAVDIKDNKGMRPLHYAAWQGRKEPMK 99
           NVN  D DG + LH +     + +L+ LL+   A V   ++    PLH A      E  +
Sbjct: 906 NVNAVDKDGNTPLHISVRAPSSAQLVRLLIRFGANVKWGNDNQQIPLHLACLYSNLETAR 727

Query: 100 LVLKAGSAVNVPSDEGHIPLHLAAQHGHYDVSEMLLQHQSNPCMVDNSGKTPLDLACEFG 159
           L+L  GS  N  S +   PLH A   G+ D+  ++LQ  S+    D     PL LAC   
Sbjct: 726 LLLHCGSCSNELSSKLWTPLHYAVIGGNVDIVRLVLQGSSDVNSPDGRNNAPLHLACMKQ 547

Query: 160 RVGVVQLLLSSNMCAALLEPRPG---DTTDPNGTSPLHLAAKNGHIDIIRLLLQAG 212
            +G+ + LL           R G   + +  NG +PLH+A  + +++++ LL   G
Sbjct: 546 CIGIARCLL-----------RHGANVNVSGYNGRTPLHIAISHHNLELVLLLYMCG 412

 Score = 65.5 bits (158), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 47/143 (32%), Positives = 68/143 (47%)
 Frame = -2

Query: 53  LHHAALNGNTELISLLLEAQAAVDIKDNKGMRPLHYAAWQGRKEPMKLVLKAGSAVNVPS 112
           LH A L  N E   LLL   +  +   +K   PLHYA   G  + ++LVL+  S VN P 
Sbjct: 768 LHLACLYSNLETARLLLHCGSCSNELSSKLWTPLHYAVIGGNVDIVRLVLQGSSDVNSPD 589

Query: 113 DEGHIPLHLAAQHGHYDVSEMLLQHQSNPCMVDNSGKTPLDLACEFGRVGVVQLLLSSNM 172
              + PLHLA       ++  LL+H +N  +   +G+TPL +A     + +V LL    M
Sbjct: 588 GRNNAPLHLACMKQCIGIARCLLRHGANVNVSGYNGRTPLHIAISHHNLELVLLLY---M 418

Query: 173 CAALLEPRPGDTTDPNGTSPLHL 195
           C A  +    D   P+  S  H+
Sbjct: 417 CGANDQLVDFDGNFPSCYSMCHI 349

 Score = 56.6 bits (135), Expect = 7e-08,   Method: Compositional matrix adjust.
 Identities = 30/102 (29%), Positives = 54/102 (52%)
 Frame = -2

Query: 50  FSALHHAALNGNTELISLLLEAQAAVDIKDNKGMRPLHYAAWQGRKEPMKLVLKAGSAVN 109
           ++ LH+A + GN +++ L+L+  + V+  D +   PLH A  +      + +L+ G+ VN
Sbjct: 678 WTPLHYAVIGGNVDIVRLVLQGSSDVNSPDGRNNAPLHLACMKQCIGIARCLLRHGANVN 499

Query: 110 VPSDEGHIPLHLAAQHGHYDVSEMLLQHQSNPCMVDNSGKTP 151
           V    G  PLH+A  H + ++  +L    +N  +VD  G  P
Sbjct: 498 VSGYNGRTPLHIAISHHNLELVLLLYMCGANDQLVDFDGNFP 373
>19166
          Length = 447

 Score = 71.6 bits (174), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 44/149 (29%), Positives = 79/149 (53%), Gaps = 3/149 (2%)
 Frame = +1

Query: 67  LLLEAQAAVDIKDNKGMRPLHYAAWQGRKEPMKLVLKAGSAVNVPSDEGHIPLHLAAQHG 126
           LLL+ +   + +   G  PLH A  + R + ++L+LK G++++  ++ G  PLH+++  G
Sbjct: 13  LLLDRKCEPNSRALNGFTPLHIACKKNRIKVVELLLKYGASIDATTESGLTPLHVSSFMG 192

Query: 127 HYDVSEMLLQHQSNPCMVDNSGKTPLDLACEFGRVGVVQLLLSSNMCAALLEPRPGDTTD 186
           H ++   L+QH + P      G+T L LA    +  ++++LL           R G   D
Sbjct: 193 HMNIVIYLIQHNAYPDTPTVRGETSLHLAARANQTDIIRILL-----------RNGAAVD 339

Query: 187 PNG---TSPLHLAAKNGHIDIIRLLLQAG 212
                  +PLH+A++ G++D + LLLQ G
Sbjct: 340 ARAREQQTPLHIASRLGNVDNVVLLLQHG 426

 Score = 62.8 bits (151), Expect = 9e-10,   Method: Compositional matrix adjust.
 Identities = 50/150 (33%), Positives = 74/150 (49%), Gaps = 1/150 (0%)
 Frame = +1

Query: 99  KLVLKAGSAVNVPSDEGHIPLHLAAQHGHYDVSEMLLQHQSNPCMVDNSGKTPLDLACEF 158
           KL+L      N  +  G  PLH+A +     V E+LL++ ++      SG TPL ++   
Sbjct: 10  KLLLDRKCEPNSRALNGFTPLHIACKKNRIKVVELLLKYGASIDATTESGLTPLHVSSFM 189

Query: 159 GRVGVVQLLLSSNMCAALLEPRPGDTTDPNGTSPLHLAAKNGHIDIIRLLLQAGIDIN-R 217
           G + +V  L+  N         P DT    G + LHLAA+    DIIR+LL+ G  ++ R
Sbjct: 190 GHMNIVIYLIQHN-------AYP-DTPTVRGETSLHLAARANQTDIIRILLRNGAAVDAR 345

Query: 218 QTKSGTALHEAALCGKTEVVRLLLDSGINA 247
             +  T LH A+  G  + V LLL  G +A
Sbjct: 346 AREQQTPLHIASRLGNVDNVVLLLQHGASA 435

 Score = 61.2 bits (147), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 44/141 (31%), Positives = 71/141 (50%), Gaps = 3/141 (2%)
 Frame = +1

Query: 31  AKLLGSTKKINVNFQDPDGFSALHHAALNGNTELISLLLEAQAAVDIKDNKGMRPLHYAA 90
           AKLL   +K   N +  +GF+ LH A      +++ LLL+  A++D     G+ PLH ++
Sbjct: 7   AKLLLD-RKCEPNSRALNGFTPLHIACKKNRIKVVELLLKYGASIDATTESGLTPLHVSS 183

Query: 91  WQGRKEPMKLVLKAGSAVNVPSDEGHIPLHLAAQHGHYDVSEMLLQHQSNPCMVDNSGK- 149
           + G    +  +++  +  + P+  G   LHLAA+    D+  +LL+   N   VD   + 
Sbjct: 184 FMGHMNIVIYLIQHNAYPDTPTVRGETSLHLAARANQTDIIRILLR---NGAAVDARARE 354

Query: 150 --TPLDLACEFGRVGVVQLLL 168
             TPL +A   G V  V LLL
Sbjct: 355 QQTPLHIASRLGNVDNVVLLL 417

 Score = 43.5 bits (101), Expect = 6e-04,   Method: Compositional matrix adjust.
 Identities = 30/97 (30%), Positives = 47/97 (48%), Gaps = 1/97 (1%)
 Frame = +1

Query: 188 NGTSPLHLAAKNGHIDIIRLLLQAGIDINRQTKSG-TALHEAALCGKTEVVRLLLDSGIN 246
           NG +PLH+A K   I ++ LLL+ G  I+  T+SG T LH ++  G   +V  L+     
Sbjct: 55  NGFTPLHIACKKNRIKVVELLLKYGASIDATTESGLTPLHVSSFMGHMNIVIYLIQHNAY 234

Query: 247 AQVRNTYSQTALDIVHQFTTSQASKEIKQLLREASAA 283
                   +T+L   H    +  +  I+ LLR  +A 
Sbjct: 235 PDTPTVRGETSL---HLAARANQTDIIRILLRNGAAV 336

 Score = 36.6 bits (83), Expect = 0.082,   Method: Compositional matrix adjust.
 Identities = 21/61 (34%), Positives = 36/61 (59%)
 Frame = +1

Query: 49  GFSALHHAALNGNTELISLLLEAQAAVDIKDNKGMRPLHYAAWQGRKEPMKLVLKAGSAV 108
           G ++LH AA    T++I +LL   AAVD +  +   PLH A+  G  + + L+L+ G++ 
Sbjct: 256 GETSLHLAARANQTDIIRILLRNGAAVDARAREQQTPLHIASRLGNVDNVVLLLQHGASA 435

Query: 109 N 109
           +
Sbjct: 436 D 438
>05924
          Length = 704

 Score = 69.3 bits (168), Expect = 1e-11,   Method: Composition-based stats.
 Identities = 42/128 (32%), Positives = 65/128 (50%)
 Frame = +1

Query: 41  NVNFQDPDGFSALHHAALNGNTELISLLLEAQAAVDIKDNKGMRPLHYAAWQGRKEPMKL 100
           N N  + DG +ALH A   G T ++ +L+ A   V+ +   G   LH A W+G  E +  
Sbjct: 139 NANSTNQDGRTALHLACRGGYTNIVQILIAAGTDVNRRTVDGKTCLHVAVWRGHTEVVVK 318

Query: 101 VLKAGSAVNVPSDEGHIPLHLAAQHGHYDVSEMLLQHQSNPCMVDNSGKTPLDLACEFGR 160
           ++ AG+ VN+P   G  PL+ AA+  +  +  +L+   +       S  TPL  A   G 
Sbjct: 319 LVNAGADVNIPDSVGCSPLYWAARSNYTAILTVLVNAGAKVNYRVKSKWTPLHAALHLGH 498

Query: 161 VGVVQLLL 168
           +GVV+ LL
Sbjct: 499 MGVVRYLL 522

 Score = 66.6 bits (161), Expect = 7e-11,   Method: Composition-based stats.
 Identities = 49/167 (29%), Positives = 83/167 (49%), Gaps = 3/167 (1%)
 Frame = +1

Query: 86  LHYAAWQGRKEPMKLVLKAGSAVNVPSDEGHIPLHLAAQHGHYDVSEMLLQHQSNPCMVD 145
           LH A     ++ +++++KAG+  N  + +G   LHLA + G+ ++ ++L+   ++     
Sbjct: 76  LHEAVSMASEDLVQMLIKAGANANSTNQDGRTALHLACRGGYTNIVQILIAAGTDVNRRT 255

Query: 146 NSGKTPLDLACEFGRVGVVQLLLSSNMCAALLEPRPGDTTDPN--GTSPLHLAAKNGHID 203
             GKT L +A   G   VV  L+++            D   P+  G SPL+ AA++ +  
Sbjct: 256 VDGKTCLHVAVWRGHTEVVVKLVNAG----------ADVNIPDSVGCSPLYWAARSNYTA 405

Query: 204 IIRLLLQAGIDINRQTKSG-TALHEAALCGKTEVVRLLLDSGINAQV 249
           I+ +L+ AG  +N + KS  T LH A   G   VVR LL  G    +
Sbjct: 406 ILTVLVNAGAKVNYRVKSKWTPLHAALHLGHMGVVRYLLLQGAETNI 546

 Score = 61.2 bits (147), Expect = 3e-09,   Method: Composition-based stats.
 Identities = 49/191 (25%), Positives = 89/191 (46%)
 Frame = +1

Query: 53  LHHAALNGNTELISLLLEAQAAVDIKDNKGMRPLHYAAWQGRKEPMKLVLKAGSAVNVPS 112
           LH A    + +L+ +L++A A  +  +  G   LH A   G    +++++ AG+ VN  +
Sbjct: 76  LHEAVSMASEDLVQMLIKAGANANSTNQDGRTALHLACRGGYTNIVQILIAAGTDVNRRT 255

Query: 113 DEGHIPLHLAAQHGHYDVSEMLLQHQSNPCMVDNSGKTPLDLACEFGRVGVVQLLLSSNM 172
            +G   LH+A   GH +V   L+   ++  + D+ G +PL  A       ++ +L+++  
Sbjct: 256 VDGKTCLHVAVWRGHTEVVVKLVNAGADVNIPDSVGCSPLYWAARSNYTAILTVLVNA-- 429

Query: 173 CAALLEPRPGDTTDPNGTSPLHLAAKNGHIDIIRLLLQAGIDINRQTKSGTALHEAALCG 232
             A +  R       +  +PLH A   GH+ ++R LL  G + N   +  T         
Sbjct: 430 -GAKVNYRV-----KSKWTPLHAALHLGHMGVVRYLLLQGAETNITVQDKT--------- 564

Query: 233 KTEVVRLLLDS 243
              VV LL+D+
Sbjct: 565 ---VVSLLMDN 588

 Score = 36.2 bits (82), Expect = 0.091,   Method: Composition-based stats.
 Identities = 19/57 (33%), Positives = 33/57 (57%), Gaps = 1/57 (1%)
 Frame = +1

Query: 205 IRLLLQAGIDIN-RQTKSGTALHEAALCGKTEVVRLLLDSGINAQVRNTYSQTALDI 260
           ++ L++ G+D+N R     T LHEA      ++V++L+ +G NA   N   +TAL +
Sbjct: 13  VQRLVKGGVDVNARFWYDSTLLHEAVSMASEDLVQMLIKAGANANSTNQDGRTALHL 183
>13462
          Length = 1388

 Score = 67.4 bits (163), Expect = 4e-11,   Method: Compositional matrix adjust.
 Identities = 75/273 (27%), Positives = 121/273 (44%), Gaps = 25/273 (9%)
 Frame = +3

Query: 42  VNFQDPDGFSALHHAALNGNTELISLLLEAQAAVDIKD---NKGMRPLHYAAWQ--GRKE 96
           VN    +G + L  A      +L+ +LL+  A  D+     NK  RPLHYA+    G   
Sbjct: 54  VNGLCGNGLTLLCVACKLNRADLVPVLLQRGALPDLPSLYLNK--RPLHYASHHSNGNLG 227

Query: 97  PMKLVLKAGSAVNVPSDEGHIPLHLAAQHGHYDVSEMLLQHQSNPCMVDNSGKTPLDLAC 156
            + ++L  G+  NV  ++G+  LHLA    + DV  +LL+   +  + D   +TPL  AC
Sbjct: 228 IVSMLLAYGAQPNVQDEDGNTALHLACSESNVDVVRLLLEWGGDVAVADIDNETPLVRAC 407

Query: 157 EFGRVGVVQLLLSSNMCAALLEPRP-----------------GDTTDPNGTSPLHLAAKN 199
               V +V LLL +         RP                 G      G + L  A+++
Sbjct: 408 LANSVELVDLLLHAGSDPNHSHGRPLEIVVRAPSLESLKLLIGAGAQVTGNTYLSFASEH 587

Query: 200 GHIDIIRLLLQAGIDINRQTKSG-TALHEAALCGKT--EVVRLLLDSGINAQVRNTYSQT 256
            ++D++++L   G+D+N   + G TALH A +  +   + VRLLL  G N  +      T
Sbjct: 588 NYLDMMKVLHNYGVDVNGTGRLGLTALHHACISQEATHDAVRLLLLWGSNPNLVTGTGDT 767

Query: 257 ALDIVHQFTTSQASKEIKQLLREASAALQVRAT 289
            L   H    + A  +++ LL   +   Q+  T
Sbjct: 768 PL---HFACQTFAVSKVRLLLMYGADVNQIDGT 857

 Score = 60.1 bits (144), Expect = 6e-09,   Method: Compositional matrix adjust.
 Identities = 74/271 (27%), Positives = 113/271 (41%), Gaps = 36/271 (13%)
 Frame = +3

Query: 43  NFQDPDGFSALHHAALNGNTELISLLLEAQAAVDIKDNKGMRPLHYAAWQGRKEPMKLVL 102
           N QD DG +ALH A    N +++ LLLE    V + D     PL  A      E + L+L
Sbjct: 264 NVQDEDGNTALHLACSESNVDVVRLLLEWGGDVAVADIDNETPLVRACLANSVELVDLLL 443

Query: 103 KAGS------------AVNVPSDE-------------GHIPLHLAAQHGHYDVSEMLLQH 137
            AGS             V  PS E             G+  L  A++H + D+ ++L  +
Sbjct: 444 HAGSDPNHSHGRPLEIVVRAPSLESLKLLIGAGAQVTGNTYLSFASEHNYLDMMKVLHNY 623

Query: 138 QSNPCMVDNSGKTPLDLAC--EFGRVGVVQLLLSSNMCAALLEPRPGDTTDPNGTSPLHL 195
             +       G T L  AC  +      V+LLL       L    P   T   G +PLH 
Sbjct: 624 GVDVNGTGRLGLTALHHACISQEATHDAVRLLL-------LWGSNPNLVTG-TGDTPLHF 779

Query: 196 AAKNGHIDIIRLLLQAGIDINRQTKSGTALHEAALCGK---------TEVVRLLLDSGIN 246
           A +   +  +RLLL  G D+N+   + T+   AAL  +          +++RLLL +G  
Sbjct: 780 ACQTFAVSKVRLLLMYGADVNQIDGTHTSPLIAALTTRRQPQNDASYLDLIRLLLAAGAR 959

Query: 247 AQVRNTYSQTALDIVHQFTTSQASKEIKQLL 277
                   +  + IV+  +++   +E+ QLL
Sbjct: 960 LS-SAVLERIKVLIVYLQSSATDKEELFQLL 1049
>14005
          Length = 1745

 Score = 65.1 bits (157), Expect = 2e-10,   Method: Composition-based stats.
 Identities = 55/191 (28%), Positives = 97/191 (50%), Gaps = 4/191 (2%)
 Frame = -1

Query: 56   AALNGNTELISLLLEAQAAVDIKD-NKGMRPLHYAAWQGRK-EPMKLVLKAGSAVNVPSD 113
            A+  G+  ++S LL+    +D+ + ++ +RP  Y A  G   E +K +++ G+ VN  S 
Sbjct: 1724 ASRMGHLAVVSELLKV-PGIDVNERDEKLRPALYFACMGNDIELVKQLVRYGARVNAYST 1548

Query: 114  EGH-IPLHLAAQHGHYDVSEMLLQHQSNPCMVDNSGKTPLDLACEFGRVGVVQLLLSSNM 172
            E    P H   + G   ++  LL+H +N       GKTPL +AC+  +  V  LL+ S  
Sbjct: 1547 ETWWTPFHACCKRGDPRIALYLLRHGANKESRTVDGKTPLVVACKNDKAEVALLLIRSGA 1368

Query: 173  CAALLEPRPGDTTDPNGTSPLHLAAKNGHIDIIRLLLQAGIDINRQTKSG-TALHEAALC 231
               +       + D    +P+H A +  +I++++ L+  G D+++    G TALH A++ 
Sbjct: 1367 NVNV-------SCDITANTPVHFACQRPNIELLKRLVLHGADVDKPNAKGHTALHVASVR 1209

Query: 232  GKTEVVRLLLD 242
            G  + V  LLD
Sbjct: 1208 GFKQHVIYLLD 1176

 Score = 52.0 bits (123), Expect = 2e-06,   Method: Composition-based stats.
 Identities = 45/141 (31%), Positives = 70/141 (49%), Gaps = 1/141 (0%)
 Frame = -1

Query: 33   LLGSTKKINVNFQDPDGFSALHHAALNGNTELISLLLEAQAAVDIKDNKGMRPLHYAAWQ 92
            L+ S   +NV+  D    + +H A    N EL+  L+   A VD  + KG   LH A+ +
Sbjct: 1385 LIRSGANVNVSC-DITANTPVHFACQRPNIELLKRLVLHGADVDKPNAKGHTALHVASVR 1209

Query: 93   GRKEPMKLVLKAGSA-VNVPSDEGHIPLHLAAQHGHYDVSEMLLQHQSNPCMVDNSGKTP 151
            G K+ +  +L    A VN  + +G+  LH+A +  H D+ E+LL   +NP   +  G TP
Sbjct: 1208 GFKQHVIYLLDFCDAEVNAATLKGNNALHIACRGKHADLVELLLHKGANPAQRNQRGWTP 1029

Query: 152  LDLACEFGRVGVVQLLLSSNM 172
             + A   GR   V  +L S +
Sbjct: 1028 RNSA---GRCXEVLDILDSRI 975

 Score = 51.2 bits (121), Expect = 3e-06,   Method: Composition-based stats.
 Identities = 50/198 (25%), Positives = 90/198 (45%), Gaps = 2/198 (1%)
 Frame = -1

Query: 50   FSALHHAALNGNTELISLLLEAQAAVDIKDNKGMRPLHYAAWQGRKEPMKLVLKAGSAVN 109
            ++  H     G+  +   LL   A  + +   G  PL  A    + E   L++++G+ VN
Sbjct: 1538 WTPFHACCKRGDPRIALYLLRHGANKESRTVDGKTPLVVACKNDKAEVALLLIRSGANVN 1359

Query: 110  VPSD-EGHIPLHLAAQHGHYDVSEMLLQHQSNPCMVDNSGKTPLDLACEFG-RVGVVQLL 167
            V  D   + P+H A Q  + ++ + L+ H ++    +  G T L +A   G +  V+ LL
Sbjct: 1358 VSCDITANTPVHFACQRPNIELLKRLVLHGADVDKPNAKGHTALHVASVRGFKQHVIYLL 1179

Query: 168  LSSNMCAALLEPRPGDTTDPNGTSPLHLAAKNGHIDIIRLLLQAGIDINRQTKSGTALHE 227
               + C A +     +     G + LH+A +  H D++ LLL  G +  ++ + G     
Sbjct: 1178 ---DFCDAEV-----NAATLKGNNALHIACRGKHADLVELLLHKGANPAQRNQRGWTPRN 1023

Query: 228  AALCGKTEVVRLLLDSGI 245
            +A  G+   V  +LDS I
Sbjct: 1022 SA--GRCXEVLDILDSRI 975
>20036
          Length = 1849

 Score = 64.7 bits (156), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 49/170 (28%), Positives = 77/170 (45%), Gaps = 7/170 (4%)
 Frame = +3

Query: 42   VNFQDPDGFSALHHAALNGNTELISLLLEAQAAVDIK--DNKGMRP-----LHYAAWQGR 94
            VN  D +G SA+H+   + N +++ LLL+ +   D+K  +  G  P     L +      
Sbjct: 864  VNLVDSNGNSAIHYCVSHCNFDIVGLLLDTEVC-DVKRPNKAGYTPTMLASLAFIQNDDH 1040

Query: 95   KEPMKLVLKAGSAVNVPSDEGHIPLHLAAQHGHYDVSEMLLQHQSNPCMVDNSGKTPLDL 154
            ++ ++ +  AG         G   L LA      D+ E+LL+  ++    D  G T L  
Sbjct: 1041 RDIIRQLFLAGDINACAEQTGQTALMLATSQCRTDMVELLLETGADCNQQDFDGSTALMC 1220

Query: 155  ACEFGRVGVVQLLLSSNMCAALLEPRPGDTTDPNGTSPLHLAAKNGHIDI 204
            ACE G   +VQLLL+   C A L       TD   ++ L +A +  H DI
Sbjct: 1221 ACEHGHTAIVQLLLAQPHCDATL-------TDNENSTALSIAMEASHKDI 1349

 Score = 45.4 bits (106), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 40/132 (30%), Positives = 64/132 (48%), Gaps = 2/132 (1%)
 Frame = +3

Query: 129 DVSEMLLQHQSNPCMVDNSGKTPLDLACEFGRVGVVQLLLSSNMCAALLEPRPGDTTDPN 188
           ++S  LL++  N  +VD++G + +          +V LLL + +C      + G T  P 
Sbjct: 834 EISHRLLEYIVN--LVDSNGNSAIHYCVSHCNFDIVGLLLDTEVCDVKRPNKAGYT--PT 1001

Query: 189 GTSPLHLAAKNGHIDIIRLLLQAGIDINR--QTKSGTALHEAALCGKTEVVRLLLDSGIN 246
             + L     + H DIIR L  AG DIN   +    TAL  A    +T++V LLL++G +
Sbjct: 1002MLASLAFIQNDDHRDIIRQLFLAG-DINACAEQTGQTALMLATSQCRTDMVELLLETGAD 1178

Query: 247 AQVRNTYSQTAL 258
              ++    TAL
Sbjct: 1179CNQQDFDGSTAL 1214

 Score = 44.3 bits (103), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 38/142 (26%), Positives = 65/142 (45%), Gaps = 7/142 (4%)
 Frame = +3

Query: 75  VDIKDNKGMRPLHYAAWQGRKEPMKLVLKAGSA-VNVPSDEGHIPLHLAA-----QHGHY 128
           V++ D+ G   +HY       + + L+L      V  P+  G+ P  LA+        H 
Sbjct: 864 VNLVDSNGNSAIHYCVSHCNFDIVGLLLDTEVCDVKRPNKAGYTPTMLASLAFIQNDDHR 1043

Query: 129 DV-SEMLLQHQSNPCMVDNSGKTPLDLACEFGRVGVVQLLLSSNMCAALLEPRPGDTTDP 187
           D+  ++ L    N C  + +G+T L LA    R  +V+LLL +            +  D 
Sbjct: 1044DIIRQLFLAGDINAC-AEQTGQTALMLATSQCRTDMVELLLETG--------ADCNQQDF 1196

Query: 188 NGTSPLHLAAKNGHIDIIRLLL 209
           +G++ L  A ++GH  I++LLL
Sbjct: 1197DGSTALMCACEHGHTAIVQLLL 1262
>21532
          Length = 460

 Score = 64.7 bits (156), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 38/114 (33%), Positives = 61/114 (53%), Gaps = 7/114 (6%)
 Frame = -1

Query: 61  NTELISLLLEAQAAVDIKDNKGMRPLHYAAWQGRKEPMKLVLKAGSA-------VNVPSD 113
           N  +I+ LL   A V+I+DN G  P   A   G    +K +L  G +       +NV  +
Sbjct: 460 NVPIINTLLSHGADVNIRDNTGCTPFANACCLGNLAAVKALLTPGESPSWSKPMINVRDN 281

Query: 114 EGHIPLHLAAQHGHYDVSEMLLQHQSNPCMVDNSGKTPLDLACEFGRVGVVQLL 167
             + PLHLA+Q GH  + E+L++H+++    ++SG  PL LA ++    VV +L
Sbjct: 280 SQNTPLHLASQEGHTAIVELLVEHKADLAAKNDSGHNPLSLARQYKHENVVAVL 119

 Score = 48.1 bits (113), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 29/93 (31%), Positives = 49/93 (52%)
 Frame = -1

Query: 130 VSEMLLQHQSNPCMVDNSGKTPLDLACEFGRVGVVQLLLSSNMCAALLEPRPGDTTDPNG 189
           +   LL H ++  + DN+G TP   AC  G +  V+ LL+     +  +P   +  D + 
Sbjct: 451 IINTLLSHGADVNIRDNTGCTPFANACCLGNLAAVKALLTPGESPSWSKPMI-NVRDNSQ 275

Query: 190 TSPLHLAAKNGHIDIIRLLLQAGIDINRQTKSG 222
            +PLHLA++ GH  I+ LL++   D+  +  SG
Sbjct: 274 NTPLHLASQEGHTAIVELLVEHKADLAAKNDSG 176

 Score = 47.4 bits (111), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 29/103 (28%), Positives = 53/103 (51%), Gaps = 7/103 (6%)
 Frame = -1

Query: 41  NVNFQDPDGFSALHHAALNGNTELISLLLE-------AQAAVDIKDNKGMRPLHYAAWQG 93
           +VN +D  G +   +A   GN   +  LL        ++  ++++DN    PLH A+ +G
Sbjct: 421 DVNIRDNTGCTPFANACCLGNLAAVKALLTPGESPSWSKPMINVRDNSQNTPLHLASQEG 242

Query: 94  RKEPMKLVLKAGSAVNVPSDEGHIPLHLAAQHGHYDVSEMLLQ 136
               ++L+++  + +   +D GH PL LA Q+ H +V  +L Q
Sbjct: 241 HTAIVELLVEHKADLAAKNDSGHNPLSLARQYKHENVVAVLQQ 113
>25470
          Length = 400

 Score = 64.3 bits (155), Expect = 3e-10,   Method: Composition-based stats.
 Identities = 39/100 (39%), Positives = 57/100 (57%)
 Frame = -3

Query: 56  AALNGNTELISLLLEAQAAVDIKDNKGMRPLHYAAWQGRKEPMKLVLKAGSAVNVPSDEG 115
           AA  G  +++  LLE  A V  +D+ G+ PLH A   G  E ++L+L+ G+  N   +  
Sbjct: 377 AAGFGRKDVVEHLLENGANVHARDDGGLIPLHNACSFGHAEVVQLLLRHGADPNARDNWN 198

Query: 116 HIPLHLAAQHGHYDVSEMLLQHQSNPCMVDNSGKTPLDLA 155
           + PLH AA  G  DV  +LLQ  ++P + +  GKT LDLA
Sbjct: 197 YTPLHEAAIKGKIDVCIVLLQQCADPNIRNTDGKTALDLA 78

 Score = 62.0 bits (149), Expect = 2e-09,   Method: Composition-based stats.
 Identities = 46/112 (41%), Positives = 62/112 (55%), Gaps = 1/112 (0%)
 Frame = -3

Query: 150 TPLDLACEFGRVGVVQLLLSSNMCAALLEPRPGDTTDPNGTSPLHLAAKNGHIDIIRLLL 209
           TP  LA  FGR  VV+ LL +    A +  R     D  G  PLH A   GH ++++LLL
Sbjct: 389 TP-SLAAGFGRKDVVEHLLEN---GANVHAR-----DDGGLIPLHNACSFGHAEVVQLLL 237

Query: 210 QAGIDIN-RQTKSGTALHEAALCGKTEVVRLLLDSGINAQVRNTYSQTALDI 260
           + G D N R   + T LHEAA+ GK +V  +LL    +  +RNT  +TALD+
Sbjct: 236 RHGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQQCADPNIRNTDGKTALDL 81

 Score = 57.4 bits (137), Expect = 4e-08,   Method: Composition-based stats.
 Identities = 52/132 (39%), Positives = 60/132 (45%), Gaps = 6/132 (4%)
 Frame = -3

Query: 108 VNVPSDEGHIPLHLAAQHGHYDVSEMLLQHQSNPCMVDNSGKTPLDLACEFGRVGVVQLL 167
           +N PS        LAA  G  DV E LL++ +N    D+ G  PL  AC FG   VVQLL
Sbjct: 395 INTPS--------LAAGFGRKDVVEHLLENGANVHARDDGGLIPLHNACSFGHAEVVQLL 240

Query: 168 LSSNMCAALLEPRPGDTTDPNGT-----SPLHLAAKNGHIDIIRLLLQAGIDIN-RQTKS 221
           L           R G   DPN       +PLH AA  G ID+  +LLQ   D N R T  
Sbjct: 239 L-----------RHG--ADPNARDNWNYTPLHEAAIKGKIDVCIVLLQQCADPNIRNTDG 99

Query: 222 GTALHEAALCGK 233
            TAL  A    K
Sbjct: 98  KTALDLADASAK 63

 Score = 54.7 bits (130), Expect = 2e-07,   Method: Composition-based stats.
 Identities = 32/80 (40%), Positives = 48/80 (60%)
 Frame = -3

Query: 89  AAWQGRKEPMKLVLKAGSAVNVPSDEGHIPLHLAAQHGHYDVSEMLLQHQSNPCMVDNSG 148
           AA  GRK+ ++ +L+ G+ V+   D G IPLH A   GH +V ++LL+H ++P   DN  
Sbjct: 377 AAGFGRKDVVEHLLENGANVHARDDGGLIPLHNACSFGHAEVVQLLLRHGADPNARDNWN 198

Query: 149 KTPLDLACEFGRVGVVQLLL 168
            TPL  A   G++ V  +LL
Sbjct: 197 YTPLHEAAIKGKIDVCIVLL 138

 Score = 44.7 bits (104), Expect = 3e-04,   Method: Composition-based stats.
 Identities = 27/82 (32%), Positives = 45/82 (54%)
 Frame = -3

Query: 41  NVNFQDPDGFSALHHAALNGNTELISLLLEAQAAVDIKDNKGMRPLHYAAWQGRKEPMKL 100
           NV+ +D  G   LH+A   G+ E++ LLL   A  + +DN    PLH AA +G+ +   +
Sbjct: 323 NVHARDDGGLIPLHNACSFGHAEVVQLLLRHGADPNARDNWNYTPLHEAAIKGKIDVCIV 144

Query: 101 VLKAGSAVNVPSDEGHIPLHLA 122
           +L+  +  N+ + +G   L LA
Sbjct: 143 LLQQCADPNIRNTDGKTALDLA 78
>28691
          Length = 562

 Score = 61.2 bits (147), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 38/105 (36%), Positives = 55/105 (52%), Gaps = 15/105 (14%)
 Frame = +1

Query: 189 GTSPLHLAAKNGHIDIIRLLLQAGIDINRQ----TKSGTALHEAALCGKTEV--VRLLLD 242
           G   LHLAAKN H+D I +L+QAG D+N +     K  TALHEA   G + V  V  LL 
Sbjct: 118 GLPALHLAAKNKHVDCIPVLVQAGADVNAKGPSTIKGNTALHEAVSVGASNVDSVDALLS 297

Query: 243 SGINAQVRNTYSQTALD---------IVHQFTTSQASKEIKQLLR 278
            G +  + N   +TA D         IV +F  +    ++++++R
Sbjct: 298 CGADQNIXNEKGETAYDLASKAGYENIVKRFAAAMGQSQLQKMIR 432
>00540
          Length = 3034

 Score = 60.8 bits (146), Expect = 4e-09,   Method: Compositional matrix adjust.
 Identities = 42/137 (30%), Positives = 69/137 (50%)
 Frame = -2

Query: 105  GSAVNVPSDEGHIPLHLAAQHGHYDVSEMLLQHQSNPCMVDNSGKTPLDLACEFGRVGVV 164
            G+ VN  +     PL  A   GH +V + L++H++   + ++ G T L +AC  G + VV
Sbjct: 3000 GAEVNQTTRSNSTPLRAACYDGHLEVVQFLVEHKAEIEIANSHGHTCLMIACYRGHLDVV 2821

Query: 165  QLLLSSNMCAALLEPRPGDTTDPNGTSPLHLAAKNGHIDIIRLLLQAGIDINRQTKSGTA 224
            + LL      A +  R        G + LH +A++G + I++LLL  G  + +     T 
Sbjct: 2820 EYLL---YLGAQVNRRS-----VKGNTALHDSAESGKLSIMKLLLSKGAKMAKDAYGQTP 2665

Query: 225  LHEAALCGKTEVVRLLL 241
            L  AA+ G  E+VR L+
Sbjct: 2664 LSAAAMTGHEEIVRYLI 2614

 Score = 55.8 bits (133), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 37/125 (29%), Positives = 59/125 (47%)
 Frame = -2

Query: 85   PLHYAAWQGRKEPMKLVLKAGSAVNVPSDEGHIPLHLAAQHGHYDVSEMLLQHQSNPCMV 144
            PL  A + G  E ++ +++  + + + +  GH  L +A   GH DV E LL   +     
Sbjct: 2961 PLRAACYDGHLEVVQFLVEHKAEIEIANSHGHTCLMIACYRGHLDVVEYLLYLGAQVNRR 2782

Query: 145  DNSGKTPLDLACEFGRVGVVQLLLSSNMCAALLEPRPGDTTDPNGTSPLHLAAKNGHIDI 204
               G T L  + E G++ +++LLLS     A          D  G +PL  AA  GH +I
Sbjct: 2781 SVKGNTALHDSAESGKLSIMKLLLSKGAKMA---------KDAYGQTPLSAAAMTGHEEI 2629

Query: 205  IRLLL 209
            +R L+
Sbjct: 2628 VRYLI 2614

 Score = 42.4 bits (98), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 32/91 (35%), Positives = 44/91 (48%), Gaps = 16/91 (17%)
 Frame = -2

Query: 185  TDPNGTSPLHLAA----------KNGH---IDIIRLLLQAGIDIN-RQTKSGTALHEAAL 230
            TDP+G SPLHLA           +  H   + + R+L++ G D N R ++   ALH A++
Sbjct: 1857 TDPDGASPLHLACMENISSFGRVRMSHFPSLSVTRILIKVGADTNARDSQGNVALHFASM 1678

Query: 231  CGKTE--VVRLLLDSGINAQVRNTYSQTALD 259
              K    VV  LL  G +A V N    T  D
Sbjct: 1677 GKKVRMAVVEALLAGGAHADVCNKNHLTLFD 1585

 Score = 31.2 bits (69), Expect = 3.5,   Method: Compositional matrix adjust.
 Identities = 21/61 (34%), Positives = 33/61 (54%)
 Frame = -2

Query: 42   VNFQDPDGFSALHHAALNGNTELISLLLEAQAAVDIKDNKGMRPLHYAAWQGRKEPMKLV 101
            VN +   G +ALH +A +G   ++ LLL   A +  KD  G  PL  AA  G +E ++ +
Sbjct: 2793 VNRRSVKGNTALHDSAESGKLSIMKLLLSKGAKM-AKDAYGQTPLSAAAMTGHEEIVRYL 2617

Query: 102  L 102
            +
Sbjct: 2616 I 2614
>20792
          Length = 441

 Score = 52.8 bits (125), Expect(2) = 3e-08,   Method: Composition-based stats.
 Identities = 32/93 (34%), Positives = 46/93 (49%)
 Frame = +2

Query: 114 EGHIPLHLAAQHGHYDVSEMLLQHQSNPCMVDNSGKTPLDLACEFGRVGVVQLLLSSNMC 173
           EG  PLH  AQ G  D    LLQ       +  +  TPL LAC   ++ V+ LLL     
Sbjct: 74  EGKKPLHETAQFGQLDCMNFLLQRGVQVDCLKRADWTPLMLACTKCQLPVISLLLKHGAD 253

Query: 174 AALLEPRPGDTTDPNGTSPLHLAAKNGHIDIIR 206
            AL+        + +G +  H+AA+ GH+DI++
Sbjct: 254 PALV--------NKDGWNSFHIAAREGHVDILK 328

 Score = 24.6 bits (52), Expect(2) = 3e-08,   Method: Composition-based stats.
 Identities = 12/21 (57%), Positives = 14/21 (66%)
 Frame = +3

Query: 221 SGTALHEAALCGKTEVVRLLL 241
           S T LH AAL G +E VR +L
Sbjct: 378 SRTPLHTAALHGHSEAVRFML 440

 Score = 38.5 bits (88), Expect = 0.021,   Method: Composition-based stats.
 Identities = 23/92 (25%), Positives = 44/92 (47%)
 Frame = +2

Query: 39  KINVNFQDPDGFSALHHAALNGNTELISLLLEAQAAVDIKDNKGMRPLHYAAWQGRKEPM 98
           ++++   + +G   LH  A  G  + ++ LL+    VD        PL  A  + +   +
Sbjct: 47  EVDLQIGNFEGKKPLHETAQFGQLDCMNFLLQRGVQVDCLKRADWTPLMLACTKCQLPVI 226

Query: 99  KLVLKAGSAVNVPSDEGHIPLHLAAQHGHYDV 130
            L+LK G+   + + +G    H+AA+ GH D+
Sbjct: 227 SLLLKHGADPALVNKDGWNSFHIAAREGHVDI 322

 Score = 32.3 bits (72), Expect = 1.4,   Method: Composition-based stats.
 Identities = 20/64 (31%), Positives = 32/64 (50%), Gaps = 1/64 (1%)
 Frame = +2

Query: 189 GTSPLHLAAKNGHIDIIRLLLQAGIDINRQTKSG-TALHEAALCGKTEVVRLLLDSGINA 247
           G  PLH  A+ G +D +  LLQ G+ ++   ++  T L  A    +  V+ LLL  G + 
Sbjct: 77  GKKPLHETAQFGQLDCMNFLLQRGVQVDCLKRADWTPLMLACTKCQLPVISLLLKHGADP 256

Query: 248 QVRN 251
            + N
Sbjct: 257 ALVN 268
>08473
          Length = 942

 Score = 55.8 bits (133), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 37/120 (30%), Positives = 56/120 (46%)
 Frame = -1

Query: 41  NVNFQDPDGFSALHHAALNGNTELISLLLEAQAAVDIKDNKGMRPLHYAAWQGRKEPMKL 100
           +V+ +D +  +ALHHA    +   +  LL+  A     +  G  PL YAA +G     KL
Sbjct: 942 DVDMRDSNDMTALHHACAGLHYGCVHALLQGGANPTCMEMGGKTPLFYAAHRGEISICKL 763

Query: 101 VLKAGSAVNVPSDEGHIPLHLAAQHGHYDVSEMLLQHQSNPCMVDNSGKTPLDLACEFGR 160
           ++  G+ VN        PL +AA+ G+ +  E LL+  +NP   D  G   L  A   G 
Sbjct: 762 LVDKGANVNAADKMLITPLMVAAREGNREAVEFLLKRGANPNTADREGHLALYYAMAAGH 583
>09180
          Length = 610

 Score = 55.5 bits (132), Expect = 1e-07,   Method: Composition-based stats.
 Identities = 34/99 (34%), Positives = 55/99 (55%), Gaps = 2/99 (2%)
 Frame = +3

Query: 183 DTTDP-NGTSPLHLAAKNGHIDIIRLLLQAGIDINRQTKSG-TALHEAALCGKTEVVRLL 240
           D   P  G + LH++A  G+I+++ +LLQAG+DIN Q   G T+LH A   G+ +  ++L
Sbjct: 144 DNAHPKTGATALHVSAAKGYINVMNVLLQAGVDINAQDADGWTSLHAAVHWGQEDSCQVL 323

Query: 241 LDSGINAQVRNTYSQTALDIVHQFTTSQASKEIKQLLRE 279
           +D   +  V+N    T  D+        A KE+ ++L E
Sbjct: 324 VDHFCDMDVKNNAGHTVFDL--------ADKEMLKVLEE 416

 Score = 42.7 bits (99), Expect = 0.001,   Method: Composition-based stats.
 Identities = 27/84 (32%), Positives = 43/84 (51%), Gaps = 4/84 (4%)
 Frame = +3

Query: 76  DIKDN----KGMRPLHYAAWQGRKEPMKLVLKAGSAVNVPSDEGHIPLHLAAQHGHYDVS 131
           +I+DN     G   LH +A +G    M ++L+AG  +N    +G   LH A   G  D  
Sbjct: 135 NIEDNAHPKTGATALHVSAAKGYINVMNVLLQAGVDINAQDADGWTSLHAAVHWGQEDSC 314

Query: 132 EMLLQHQSNPCMVDNSGKTPLDLA 155
           ++L+ H  +  + +N+G T  DLA
Sbjct: 315 QVLVDHFCDMDVKNNAGHTVFDLA 386

 Score = 32.7 bits (73), Expect = 1.2,   Method: Composition-based stats.
 Identities = 25/84 (29%), Positives = 40/84 (47%), Gaps = 3/84 (3%)
 Frame = +3

Query: 40  INVNFQDPDGFSALHHAALNGNTELISLLLEAQAAVDIKDNKGMRPLHYAAWQGRK---E 96
           +++N QD DG+++LH A   G  +   +L++    +D+K+N G      A  +  K   E
Sbjct: 237 VDINAQDADGWTSLHAAVHWGQEDSCQVLVDHFCDMDVKNNAGHTVFDLADKEMLKVLEE 416

Query: 97  PMKLVLKAGSAVNVPSDEGHIPLH 120
             K   K  +A    SD  H P H
Sbjct: 417 LKKKQAKLRTASESNSDIIHTPGH 488
>02055
          Length = 1740

 Score = 54.3 bits (129), Expect = 4e-07,   Method: Composition-based stats.
 Identities = 44/153 (28%), Positives = 73/153 (47%), Gaps = 2/153 (1%)
 Frame = +3

Query: 68  LLEAQAAVDIKDNKGMRPLHYAAWQGRKEPMKLVLKAGSAVNVPSD-EGHIPLHLAAQ-H 125
           L+   A VD  +  G  PLH A      E M  +++ G+ VN  +      PLH+A +  
Sbjct: 381 LIRCGADVDFCNMFGDTPLHIATVHANHEAMGALVRNGANVNARAKFLNSTPLHVACRLR 560

Query: 126 GHYDVSEMLLQHQSNPCMVDNSGKTPLDLACEFGRVGVVQLLLSSNMCAALLEPRPGDTT 185
           G  +V+ +L+Q  +   + D +G TPL +AC+     VV +LL S       +P    T 
Sbjct: 561 GQQEVA-LLIQLGARIDVNDATGTTPLQMACKRADPAVVNILLRS-------QPSIVRTE 716

Query: 186 DPNGTSPLHLAAKNGHIDIIRLLLQAGIDINRQ 218
           D N       A +   + I+++L +AG+ +N +
Sbjct: 717 DANKL--FKYAIQKRQLHIVKMLCEAGVAVNYE 809
>15359
          Length = 780

 Score = 53.9 bits (128), Expect = 5e-07,   Method: Compositional matrix adjust.
 Identities = 34/90 (37%), Positives = 52/90 (57%), Gaps = 3/90 (3%)
 Frame = +1

Query: 63  ELISLLLEAQAAVDIKD-NKGMRPLHYAAWQGRKEPMKLVL-KAGSAVNVPSDEGHIPLH 120
           E+  LL +      +KD   G   LH+AA  G+ E +K++  K G  +N  S  G+ PLH
Sbjct: 289 EMFRLLNKNARLAKVKDIANGYTALHWAAKFGKPEVVKMLANKIGVEINQRSHGGYTPLH 468

Query: 121 LAAQHGHYDVSEMLLQ-HQSNPCMVDNSGK 149
           LAA HGH D+ E+L+  ++++  + D SGK
Sbjct: 469 LAAIHGHEDIIELLVTGYKADANIRDYSGK 558

 Score = 41.2 bits (95), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 31/85 (36%), Positives = 43/85 (50%), Gaps = 4/85 (4%)
 Frame = +1

Query: 129 DVSEM--LLQHQSNPCMVDN--SGKTPLDLACEFGRVGVVQLLLSSNMCAALLEPRPGDT 184
           D  EM  LL   +    V +  +G T L  A +FG+  VV++L  +N     +  R    
Sbjct: 280 DYHEMFRLLNKNARLAKVKDIANGYTALHWAAKFGKPEVVKML--ANKIGVEINQR---- 441

Query: 185 TDPNGTSPLHLAAKNGHIDIIRLLL 209
               G +PLHLAA +GH DII LL+
Sbjct: 442 -SHGGYTPLHLAAIHGHEDIIELLV 513
>28113
          Length = 449

 Score = 53.5 bits (127), Expect = 5e-07,   Method: Compositional matrix adjust.
 Identities = 33/104 (31%), Positives = 57/104 (54%), Gaps = 1/104 (0%)
 Frame = -3

Query: 53  LHHAALNGNTELISLLLEAQAAVDIKDNKGMRPLHYAAWQGRKEPMKLVLKAGSAVNVPS 112
           LH +A  G+   +  LL        KD+     +HYA+W G  + ++++L AG + N+ +
Sbjct: 321 LHASAAQGDVHHVQSLLNHGHHHSKKDSIAWAAIHYASWYGSADVVEILLDAGCSPNLTN 142

Query: 113 DEGHIPLHLAAQHGHYDVSEMLLQHQS-NPCMVDNSGKTPLDLA 155
            E   PLH+AA+ G  DV+E L+Q ++ +  + D  GK  +D+ 
Sbjct: 141 SELLTPLHIAAKKGFPDVAEHLVQAEAIDLNLRDKDGKRAIDIC 10

 Score = 43.9 bits (102), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 33/106 (31%), Positives = 49/106 (46%), Gaps = 1/106 (0%)
 Frame = -3

Query: 118 PLHLAAQHGHYDVSEMLLQHQSNPCMVDNSGKTPLDLACEFGRVGVVQLLLSSNMCAALL 177
           PLH +A  G     + LL H  +    D+     +  A  +G   VV++LL +     L 
Sbjct: 324 PLHASAAQGDVHHVQSLLNHGHHHSKKDSIAWAAIHYASWYGSADVVEILLDAGCSPNL- 148

Query: 178 EPRPGDTTDPNGTSPLHLAAKNGHIDIIRLLLQA-GIDINRQTKSG 222
                  T+    +PLH+AAK G  D+   L+QA  ID+N + K G
Sbjct: 147 -------TNSELLTPLHIAAKKGFPDVAEHLVQAEAIDLNLRDKDG 31

 Score = 36.6 bits (83), Expect = 0.068,   Method: Compositional matrix adjust.
 Identities = 26/85 (30%), Positives = 44/85 (51%), Gaps = 1/85 (1%)
 Frame = -3

Query: 177 LEPRPGDTTDPNGTSPLHLAAKNGHIDIIRLLLQAGIDINRQ-TKSGTALHEAALCGKTE 235
           +EPR  D        PLH +A  G +  ++ LL  G   +++ + +  A+H A+  G  +
Sbjct: 351 VEPRWRDKY------PLHASAAQGDVHHVQSLLNHGHHHSKKDSIAWAAIHYASWYGSAD 190

Query: 236 VVRLLLDSGINAQVRNTYSQTALDI 260
           VV +LLD+G +  + N+   T L I
Sbjct: 189 VVEILLDAGCSPNLTNSELLTPLHI 115

 Score = 33.5 bits (75), Expect = 0.68,   Method: Compositional matrix adjust.
 Identities = 14/49 (28%), Positives = 34/49 (69%)
 Frame = -3

Query: 45  QDPDGFSALHHAALNGNTELISLLLEAQAAVDIKDNKGMRPLHYAAWQG 93
           +D   ++A+H+A+  G+ +++ +LL+A  + ++ +++ + PLH AA +G
Sbjct: 246 KDSIAWAAIHYASWYGSADVVEILLDAGCSPNLTNSELLTPLHIAAKKG 100
>28494
          Length = 463

 Score = 52.4 bits (124), Expect = 1e-06,   Method: Composition-based stats.
 Identities = 24/66 (36%), Positives = 40/66 (60%)
 Frame = -1

Query: 41  NVNFQDPDGFSALHHAALNGNTELISLLLEAQAAVDIKDNKGMRPLHYAAWQGRKEPMKL 100
           ++N  + DG +ALH A ++ N +++  L+E  A VD+ DN+G  PLH  A  G  E  + 
Sbjct: 244 DINTANVDGLTALHQACIDDNLDMVEFLVEQNADVDVCDNEGWTPLHATASCGFTEIARY 65

Query: 101 VLKAGS 106
           +L+ G+
Sbjct: 64  LLENGA 47

 Score = 45.8 bits (107), Expect = 1e-04,   Method: Composition-based stats.
 Identities = 23/69 (33%), Positives = 39/69 (56%), Gaps = 1/69 (1%)
 Frame = -1

Query: 183 DTTDPNGTSPLHLAAKNGHIDIIRLLLQAGIDINRQTKSG-TALHEAALCGKTEVVRLLL 241
           +T + +G + LH A  + ++D++  L++   D++     G T LH  A CG TE+ R LL
Sbjct: 238 NTANVDGLTALHQACIDDNLDMVEFLVEQNADVDVCDNEGWTPLHATASCGFTEIARYLL 59

Query: 242 DSGINAQVR 250
           ++G N   R
Sbjct: 58  ENGANGGCR 32

 Score = 33.1 bits (74), Expect = 0.90,   Method: Composition-based stats.
 Identities = 32/106 (30%), Positives = 46/106 (43%), Gaps = 2/106 (1%)
 Frame = -1

Query: 179 PRPGDTTDPNGTSPLHLAA-KNGHIDIIRLLLQAGIDINRQTKSG-TALHEAALCGKTEV 236
           PRP           + LAA  +G  D ++ LL+ G DIN     G TALH+A +    ++
Sbjct: 352 PRPSAKKVKFQDGCVFLAACSSGDRDEVKKLLERGADINTANVDGLTALHQACIDDNLDM 173

Query: 237 VRLLLDSGINAQVRNTYSQTALDIVHQFTTSQASKEIKQLLREASA 282
           V  L++   +  V +    T L      T S    EI + L E  A
Sbjct: 172 VEFLVEQNADVDVCDNEGWTPL----HATASCGFTEIARYLLENGA 47
>15772
          Length = 1282

 Score = 49.3 bits (116), Expect = 1e-05,   Method: Composition-based stats.
 Identities = 33/101 (32%), Positives = 49/101 (48%), Gaps = 2/101 (1%)
 Frame = -3

Query: 41   NVNFQDPDG--FSALHHAALNGNTELISLLLEAQAAVDIKDNKGMRPLHYAAWQGRKEPM 98
            +VN +DPD    +ALH A   G  E I LLL+  A    + + G  P H AA   R   +
Sbjct: 1208 DVNLKDPDAGNKTALHWACQKGFVECIRLLLDHGAKGTARTDTGWTPAHCAAECNRVTAL 1029

Query: 99   KLVLKAGSAVNVPSDEGHIPLHLAAQHGHYDVSEMLLQHQS 139
            + +  A   V++    G  P  +A  +GH D +  LLQ ++
Sbjct: 1028 RALHAALVPVDLTDKYGDTPRRIATLYGHRDCARYLLQAEA 906

 Score = 38.5 bits (88), Expect = 0.022,   Method: Composition-based stats.
 Identities = 39/134 (29%), Positives = 53/134 (39%), Gaps = 28/134 (20%)
 Frame = -3

Query: 117  IPLHLAAQHGHYDVSEMLLQ---HQSNPCMVDNSGKTPLDLACEFGRVGVVQLLL----- 168
            + LH AA  G YD  E  ++   +  N    D   KT L  AC+ G V  ++LLL     
Sbjct: 1280 LELHDAASTGDYDALEDYVKSGIYDVNLKDPDAGNKTALHWACQKGFVECIRLLLDHGAK 1101

Query: 169  ---------SSNMCAALLEP-----------RPGDTTDPNGTSPLHLAAKNGHIDIIRLL 208
                     +   CAA                P D TD  G +P  +A   GH D  R L
Sbjct: 1100 GTARTDTGWTPAHCAAECNRVTALRALHAALVPVDLTDKYGDTPRRIATLYGHRDCARYL 921

Query: 209  LQAGIDINRQTKSG 222
            LQA  ++  + + G
Sbjct: 920  LQAEAEVAERRRKG 879

 Score = 34.3 bits (77), Expect = 0.37,   Method: Composition-based stats.
 Identities = 24/62 (38%), Positives = 31/62 (50%), Gaps = 4/62 (6%)
 Frame = -3

Query: 193  LHLAAKNGHIDIIRLLLQAGI-DINRQTKSG---TALHEAALCGKTEVVRLLLDSGINAQ 248
            LH AA  G  D +   +++GI D+N +       TALH A   G  E +RLLLD G    
Sbjct: 1274 LHDAASTGDYDALEDYVKSGIYDVNLKDPDAGNKTALHWACQKGFVECIRLLLDHGAKGT 1095

Query: 249  VR 250
             R
Sbjct: 1094 AR 1089
>25464
          Length = 440

 Score = 49.3 bits (116), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 31/103 (30%), Positives = 54/103 (52%), Gaps = 5/103 (4%)
 Frame = -3

Query: 73  AAVDIKDNKGMRPLHYAAWQGRKEPMKLVLKAGSA-VNVPSDEGHIPLHLAAQHGHYDVS 131
           A ++++D+ G   L YA   GR++ ++ +LK     +N P ++G+ P+H AA   + ++ 
Sbjct: 438 AYLNVRDSMGRTALSYACLNGRQDIVRCILKEDVLDINEPDNDGNTPIHHAAISANPNIV 259

Query: 132 EML----LQHQSNPCMVDNSGKTPLDLACEFGRVGVVQLLLSS 170
            ML     +   NP   +  G TPL LAC+ G       LL++
Sbjct: 258 RMLAEAFYKFGLNPDKRNKLGYTPLLLACKGGNYVSAYTLLTT 130
>20884
          Length = 712

 Score = 38.9 bits (89), Expect(2) = 1e-05,   Method: Compositional matrix adjust.
 Identities = 25/54 (46%), Positives = 33/54 (61%), Gaps = 2/54 (3%)
 Frame = +2

Query: 189 GTSPLHLAAKNGHIDIIRLLLQAGIDINRQT-KSG-TALHEAALCGKTEVVRLL 240
           G +  HLA + GH+ I+ LLL+ G +IN Q  KSG T LH AA  G  + + LL
Sbjct: 551 GYTCAHLALQTGHLHILPLLLERGANINEQDGKSGRTLLHMAADLGYLQALELL 712

 Score = 29.6 bits (65), Expect(2) = 1e-05,   Method: Compositional matrix adjust.
 Identities = 20/62 (32%), Positives = 29/62 (46%)
 Frame = +1

Query: 108 VNVPSDEGHIPLHLAAQHGHYDVSEMLLQHQSNPCMVDNSGKTPLDLACEFGRVGVVQLL 167
           +N+P+     PLHLA       V   L+   +     D  G T L +AC  G   +V+LL
Sbjct: 277 INIPNMLHQTPLHLAVATRQMWVVRRLMVAGAAMEAPDYCGNTALHIACREGMTEMVKLL 456

Query: 168 LS 169
           L+
Sbjct: 457 LT 462

 Score = 39.7 bits (91), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 28/87 (32%), Positives = 43/87 (49%), Gaps = 3/87 (3%)
 Frame = +1

Query: 158 FGRVGVVQLLLSSNMCAALLEPRPGDTTDPNGT--SPLHLAAKNGHIDIIRLLLQAGIDI 215
           +  + ++ LL   ++    + P P     PN    +PLHLA     + ++R L+ AG  +
Sbjct: 199 YLHMSIIHLLPDVSLKVISVAPSPDYINIPNMLHQTPLHLAVATRQMWVVRRLMVAGAAM 378

Query: 216 NRQTKSG-TALHEAALCGKTEVVRLLL 241
                 G TALH A   G TE+V+LLL
Sbjct: 379 EAPDYCGNTALHIACREGMTEMVKLLL 459

 Score = 34.3 bits (77), Expect = 0.35,   Method: Composition-based stats.
 Identities = 20/55 (36%), Positives = 31/55 (56%), Gaps = 1/55 (1%)
 Frame = +2

Query: 114 EGHIPLHLAAQHGHYDVSEMLLQHQSNPCMVD-NSGKTPLDLACEFGRVGVVQLL 167
           EG+   HLA Q GH  +  +LL+  +N    D  SG+T L +A + G +  ++LL
Sbjct: 548 EGYTCAHLALQTGHLHILPLLLERGANINEQDGKSGRTLLHMAADLGYLQALELL 712

 Score = 33.9 bits (76), Expect = 0.49,   Method: Compositional matrix adjust.
 Identities = 26/95 (27%), Positives = 50/95 (52%), Gaps = 4/95 (4%)
 Frame = +1

Query: 45  QDPDGFSALHHAALNGNTELISLLLEAQA----AVDIKDNKGMRPLHYAAWQGRKEPMKL 100
           QD DG S LH + ++   + +SL + + A     ++I +     PLH A    +   ++ 
Sbjct: 178 QDEDGDSYLHMSIIHLLPD-VSLKVISVAPSPDYINIPNMLHQTPLHLAVATRQMWVVRR 354

Query: 101 VLKAGSAVNVPSDEGHIPLHLAAQHGHYDVSEMLL 135
           ++ AG+A+  P   G+  LH+A + G  ++ ++LL
Sbjct: 355 LMVAGAAMEAPDYCGNTALHIACREGMTEMVKLLL 459

 Score = 30.8 bits (68), Expect = 4.7,   Method: Compositional matrix adjust.
 Identities = 28/100 (28%), Positives = 51/100 (51%), Gaps = 3/100 (3%)
 Frame = +1

Query: 113 DEGHIPLHLAAQHGHYDVSEMLLQHQSNPCMVDNSG---KTPLDLACEFGRVGVVQLLLS 169
           ++G   LH++  H   DVS  ++    +P  ++      +TPL LA    ++ VV+ L+ 
Sbjct: 184 EDGDSYLHMSIIHLLPDVSLKVISVAPSPDYINIPNMLHQTPLHLAVATRQMWVVRRLMV 363

Query: 170 SNMCAALLEPRPGDTTDPNGTSPLHLAAKNGHIDIIRLLL 209
           +   AA+  P      D  G + LH+A + G  ++++LLL
Sbjct: 364 AG--AAMEAP------DYCGNTALHIACREGMTEMVKLLL 459
>12417
          Length = 954

 Score = 48.1 bits (113), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 28/73 (38%), Positives = 38/73 (52%), Gaps = 1/73 (1%)
 Frame = +2

Query: 193 LHLAAKNGHIDIIRLLLQAGIDINRQTKSG-TALHEAALCGKTEVVRLLLDSGINAQVRN 251
           L +AA  G   +   L+Q G D+N  T+ G T LH A+  G   +V LLL+ G +    +
Sbjct: 245 LAMAANRGLDKMCSQLIQTGADVNSATEHGRTPLHXASAQGHGHIVDLLLEKGADIDAED 424

Query: 252 TYSQTALDIVHQF 264
            Y  TAL I  QF
Sbjct: 425 DYGDTALSIADQF 463

 Score = 42.0 bits (97), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 23/74 (31%), Positives = 41/74 (55%)
 Frame = +2

Query: 86  LHYAAWQGRKEPMKLVLKAGSAVNVPSDEGHIPLHLAAQHGHYDVSEMLLQHQSNPCMVD 145
           L  AA +G  +    +++ G+ VN  ++ G  PLH A+  GH  + ++LL+  ++    D
Sbjct: 245 LAMAANRGLDKMCSQLIQTGADVNSATEHGRTPLHXASAQGHGHIVDLLLEKGADIDAED 424

Query: 146 NSGKTPLDLACEFG 159
           + G T L +A +FG
Sbjct: 425 DYGDTALSIADQFG 466

 Score = 37.7 bits (86), Expect = 0.030,   Method: Compositional matrix adjust.
 Identities = 28/85 (32%), Positives = 43/85 (50%), Gaps = 7/85 (8%)
 Frame = +2

Query: 164 VQLLLSSN-----MCAALLEPRPG-DTTDPNGTSPLHLAAKNGHIDIIRLLLQAGIDINR 217
           V L +++N     MC+ L++     ++   +G +PLH A+  GH  I+ LLL+ G DI+ 
Sbjct: 239 VALAMAANRGLDKMCSQLIQTGADVNSATEHGRTPLHXASAQGHGHIVDLLLEKGADIDA 418

Query: 218 QTKSG-TALHEAALCGKTEVVRLLL 241
           +   G TAL  A   G     R L 
Sbjct: 419 EDDYGDTALSIADQFGFKSCGRXLF 493
>16561
          Length = 2029

 Score = 47.0 bits (110), Expect = 5e-05,   Method: Composition-based stats.
 Identities = 31/98 (31%), Positives = 49/98 (50%), Gaps = 3/98 (3%)
 Frame = -3

Query: 68   LLEAQAAVDIKDNKGMRPLHYAAWQGRKEPMKLVLKAGSAVNVPSDEGHIPLHLAAQH-- 125
            LL  +A VDI++N+   PL  A  QG    ++L++ A + +NV  ++G   LHLA     
Sbjct: 1553 LLRNRAEVDIRNNRQQTPLLLAVSQGHSSLIELLVHAQADINVSDEDGDTCLHLALMRQT 1374

Query: 126  -GHYDVSEMLLQHQSNPCMVDNSGKTPLDLACEFGRVG 162
                D S ML   +S   M ++  +T   +AC   + G
Sbjct: 1373 VATEDSSRMLDSIRSQLGMGEDEAQTGAAIACYLAQQG 1260

 Score = 45.8 bits (107), Expect = 1e-04,   Method: Composition-based stats.
 Identities = 60/226 (26%), Positives = 93/226 (41%), Gaps = 30/226 (13%)
 Frame = -3

Query: 48   DGFSALHHAALNGNTELISLLLEAQAAVDIKDNKGMRPLHYAAWQGRKEPMKLVLKAGSA 107
            DG +ALH++A     +++ LLL   A ++  +N G   LH A  +   + + ++L  G  
Sbjct: 2015 DGDTALHYSAFGNQPDVLQLLLSKGAKINALNNGGCSTLHVAVNKQHIKCVHVLLNXGCD 1836

Query: 108  VNVPSDEGHIPLHLA------------------AQHGHYDVSEM--LLQHQSNPCMVDNS 147
            VN     G   LH A                         V+ M  ++Q     C+  ++
Sbjct: 1835 VNXQDAYGDTALHDAIGKRAVKSLTSLSITLALISPSETSVASMSSIMQP*RAMCLPRSA 1656

Query: 148  GKTPLDLACEFGR-VGVVQ----LLLSSNMCAA-LLEPRPG-DTTDPNGTSPLHLAAKNG 200
              T +D     G+ +G +     L + + M    LL  R   D  +    +PL LA   G
Sbjct: 1655 SCTNVDRLWT*GKMMGFLHFTWLL*MDTRMLQQHLLRNRAEVDIRNNRQQTPLLLAVSQG 1476

Query: 201  HIDIIRLLLQAGIDINRQTKSG-TALHEAAL--CGKTEVVRLLLDS 243
            H  +I LL+ A  DIN   + G T LH A +     TE    +LDS
Sbjct: 1475 HSSLIELLVHAQADINVSDEDGDTCLHLALMRQTVATEDSSRMLDS 1338

 Score = 45.1 bits (105), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 23/68 (33%), Positives = 37/68 (54%), Gaps = 1/68 (1%)
 Frame = -2

Query: 40   INVNFQDPDGFSALHHAALNGNTELISLLL-EAQAAVDIKDNKGMRPLHYAAWQGRKEPM 98
            I+  F++  GF+ LHHAAL GN      +L + +  VD++ + G   LH AA  G K+  
Sbjct: 1740 IDFTFRNKRGFNVLHHAALKGNVFATERVLHKCRQIVDLRKDDGFSALHLAALNGHKDVA 1561

Query: 99   KLVLKAGS 106
              +++  S
Sbjct: 1560 AALIEESS 1537

 Score = 38.1 bits (87), Expect = 0.025,   Method: Composition-based stats.
 Identities = 31/104 (29%), Positives = 51/104 (49%)
 Frame = -3

Query: 76   DIKDNKGMRPLHYAAWQGRKEPMKLVLKAGSAVNVPSDEGHIPLHLAAQHGHYDVSEMLL 135
            DI+D  G   LHY+A+  + + ++L+L  G+ +N  ++ G   LH+A    H     +LL
Sbjct: 2024 DIRD--GDTALHYSAFGNQPDVLQLLLSKGAKINALNNGGCSTLHVAVNKQHIKCVHVLL 1851

Query: 136  QHQSNPCMVDNSGKTPLDLACEFGRVGVVQLLLSSNMCAALLEP 179
                +    D  G T L  A   G+   V+ L S ++  AL+ P
Sbjct: 1850 NXGCDVNXQDAYGDTALHDA--IGKRA-VKSLTSLSITLALISP 1728
>30463
          Length = 412

 Score = 46.6 bits (109), Expect = 8e-05,   Method: Composition-based stats.
 Identities = 26/79 (32%), Positives = 41/79 (51%), Gaps = 1/79 (1%)
 Frame = -1

Query: 187 PNGTSPLHLAAKNGHIDIIRLLLQAGIDIN-RQTKSGTALHEAALCGKTEVVRLLLDSGI 245
           P G +  HLAA NGH + + +L   G  I+ R     T LH A+  G  E V+ L+ +  
Sbjct: 394 PTGYTATHLAAMNGHSNAVMVLNIMGASIDCRTVDKQTPLHLASSAGHIECVKCLVANKA 215

Query: 246 NAQVRNTYSQTALDIVHQF 264
           +    + +S+TA D+  Q+
Sbjct: 214 SLTAEDAFSRTAYDLADQY 158

 Score = 46.2 bits (108), Expect = 9e-05,   Method: Composition-based stats.
 Identities = 27/102 (26%), Positives = 51/102 (50%)
 Frame = -1

Query: 44  FQDPDGFSALHHAALNGNTELISLLLEAQAAVDIKDNKGMRPLHYAAWQGRKEPMKLVLK 103
            + P G++A H AA+NG++  + +L    A++D +      PLH A+  G  E +K ++ 
Sbjct: 403 LETPTGYTATHLAAMNGHSNAVMVLNIMGASIDCRTVDKQTPLHLASSAGHIECVKCLVA 224

Query: 104 AGSAVNVPSDEGHIPLHLAAQHGHYDVSEMLLQHQSNPCMVD 145
             +++            LA Q+G  DV++ L     + C++D
Sbjct: 223 NKASLTAEDAFSRTAYDLADQYGQNDVADFL-----HHCLLD 113

 Score = 40.8 bits (94), Expect = 0.004,   Method: Composition-based stats.
 Identities = 22/86 (25%), Positives = 43/86 (50%)
 Frame = -1

Query: 82  GMRPLHYAAWQGRKEPMKLVLKAGSAVNVPSDEGHIPLHLAAQHGHYDVSEMLLQHQSNP 141
           G    H AA  G    + ++   G++++  + +   PLHLA+  GH +  + L+ ++++ 
Sbjct: 388 GYTATHLAAMNGHSNAVMVLNIMGASIDCRTVDKQTPLHLASSAGHIECVKCLVANKASL 209

Query: 142 CMVDNSGKTPLDLACEFGRVGVVQLL 167
              D   +T  DLA ++G+  V   L
Sbjct: 208 TAEDAFSRTAYDLADQYGQNDVADFL 131
>38834
          Length = 496

 Score = 46.2 bits (108), Expect = 9e-05,   Method: Composition-based stats.
 Identities = 28/96 (29%), Positives = 50/96 (52%)
 Frame = -1

Query: 121 LAAQHGHYDVSEMLLQHQSNPCMVDNSGKTPLDLACEFGRVGVVQLLLSSNMCAALLEPR 180
           +A   GH D++EML +      +V+ +G TP  L+  F +  +   L+  N  A +    
Sbjct: 496 IACSSGHLDIAEMLHRRGVQINVVNINGYTPXHLSVYFNKFDITHFLVKIN--AEI---- 335

Query: 181 PGDTTDPNGTSPLHLAAKNGHIDIIRLLLQAGIDIN 216
             +T +  G +P++LAA  G+  I+ L++ AG  +N
Sbjct: 334 --NTVNNAGQTPVYLAALRGNSKILALMVNAGCKVN 233

 Score = 41.2 bits (95), Expect = 0.003,   Method: Composition-based stats.
 Identities = 20/82 (24%), Positives = 45/82 (54%)
 Frame = -1

Query: 89  AAWQGRKEPMKLVLKAGSAVNVPSDEGHIPLHLAAQHGHYDVSEMLLQHQSNPCMVDNSG 148
           A   G  +  +++ + G  +NV +  G+ P HL+     +D++  L++  +    V+N+G
Sbjct: 493 ACSSGHLDIAEMLHRRGVQINVVNINGYTPXHLSVYFNKFDITHFLVKINAEINTVNNAG 314

Query: 149 KTPLDLACEFGRVGVVQLLLSS 170
           +TP+ LA   G   ++ L++++
Sbjct: 313 QTPVYLAALRGNSKILALMVNA 248

 Score = 32.0 bits (71), Expect = 1.8,   Method: Composition-based stats.
 Identities = 14/80 (17%), Positives = 40/80 (50%)
 Frame = -1

Query: 56  AALNGNTELISLLLEAQAAVDIKDNKGMRPLHYAAWQGRKEPMKLVLKAGSAVNVPSDEG 115
           A  +G+ ++  +L      +++ +  G  P H + +  + +    ++K  + +N  ++ G
Sbjct: 493 ACSSGHLDIAEMLHRRGVQINVVNINGYTPXHLSVYFNKFDITHFLVKINAEINTVNNAG 314

Query: 116 HIPLHLAAQHGHYDVSEMLL 135
             P++LAA  G+  +  +++
Sbjct: 313 QTPVYLAALRGNSKILALMV 254
>33144
          Length = 272

 Score = 45.4 bits (106), Expect = 2e-04,   Method: Composition-based stats.
 Identities = 28/72 (38%), Positives = 36/72 (50%), Gaps = 1/72 (1%)
 Frame = +3

Query: 85  PLHYAAWQGRKEPMKLVLKAGS-AVNVPSDEGHIPLHLAAQHGHYDVSEMLLQHQSNPCM 143
           PLH AA  GR     +++K G  AVNV       PLH A Q     + ++LL   +NP +
Sbjct: 21  PLHLAAMNGRTAIAGVLVKKGEVAVNVVDKHKRTPLHYAVQTCELTIIDLLLGRDANPNI 200

Query: 144 VDNSGKTPLDLA 155
            D  G TP  LA
Sbjct: 201 QDVDGNTPTHLA 236

 Score = 40.8 bits (94), Expect = 0.004,   Method: Composition-based stats.
 Identities = 24/76 (31%), Positives = 41/76 (53%), Gaps = 1/76 (1%)
 Frame = +3

Query: 48  DGFSALHHAALNGNTELISLLLE-AQAAVDIKDNKGMRPLHYAAWQGRKEPMKLVLKAGS 106
           + ++ LH AA+NG T +  +L++  + AV++ D     PLHYA        + L+L   +
Sbjct: 9   ENWAPLHLAAMNGRTAIAGVLVKKGEVAVNVVDKHKRTPLHYAVQTCELTIIDLLLGRDA 188

Query: 107 AVNVPSDEGHIPLHLA 122
             N+   +G+ P HLA
Sbjct: 189 NPNIQDVDGNTPTHLA 236

 Score = 32.7 bits (73), Expect = 1.1,   Method: Composition-based stats.
 Identities = 24/84 (28%), Positives = 41/84 (48%), Gaps = 1/84 (1%)
 Frame = +3

Query: 114 EGHIPLHLAAQHGHYDVSEMLLQH-QSNPCMVDNSGKTPLDLACEFGRVGVVQLLLSSNM 172
           E   PLHLAA +G   ++ +L++  +    +VD   +TPL  A +   + ++ LLL  + 
Sbjct: 9   ENWAPLHLAAMNGRTAIAGVLVKKGEVAVNVVDKHKRTPLHYAVQTCELTIIDLLLGRDA 188

Query: 173 CAALLEPRPGDTTDPNGTSPLHLA 196
                     +  D +G +P HLA
Sbjct: 189 NP--------NIQDVDGNTPTHLA 236
>17893
          Length = 453

 Score = 43.5 bits (101), Expect = 6e-04,   Method: Composition-based stats.
 Identities = 25/61 (40%), Positives = 35/61 (57%), Gaps = 1/61 (1%)
 Frame = -3

Query: 201 HIDIIRLLLQAGIDINRQTKSG-TALHEAALCGKTEVVRLLLDSGINAQVRNTYSQTALD 259
           ++D +  LL+ G  IN   ++G T LHEAA     +V R LLD GIN    + Y +TAL 
Sbjct: 184 NLDFVDSLLKNGASINIMDRTGQTLLHEAARAWHVDVTRWLLDHGINIDQPDYYGRTALH 5

Query: 260 I 260
           +
Sbjct: 4   V 2

 Score = 36.6 bits (83), Expect = 0.073,   Method: Composition-based stats.
 Identities = 20/52 (38%), Positives = 28/52 (53%)
 Frame = -3

Query: 101 VLKAGSAVNVPSDEGHIPLHLAAQHGHYDVSEMLLQHQSNPCMVDNSGKTPL 152
           +LK G+++N+    G   LH AA+  H DV+  LL H  N    D  G+T L
Sbjct: 163 LLKNGASINIMDRTGQTLLHEAARAWHVDVTRWLLDHGINIDQPDYYGRTAL 8
>27067
          Length = 409

 Score = 42.0 bits (97), Expect = 0.002,   Method: Composition-based stats.
 Identities = 27/72 (37%), Positives = 40/72 (55%), Gaps = 2/72 (2%)
 Frame = +1

Query: 189 GTSPLHLAAKNGHIDIIRLLLQA-GIDINRQTKS-GTALHEAALCGKTEVVRLLLDSGIN 246
           G+S +H A K  + DI+R LL   G++ N    S  T + EAA  G+ E + +LLD G N
Sbjct: 25  GSSAVHEAIKVNNTDILRYLLTVPGLECNAVNASQKTPVMEAASRGRIECLTMLLDHGCN 204

Query: 247 AQVRNTYSQTAL 258
            +  N   +TA+
Sbjct: 205 TEGENIRGKTAM 240

 Score = 29.6 bits (65), Expect = 8.2,   Method: Composition-based stats.
 Identities = 35/121 (28%), Positives = 50/121 (41%), Gaps = 5/121 (4%)
 Frame = +1

Query: 81  KGMRPLHYAAWQGRKEPMKLVLKA-GSAVNVPSDEGHIPLHLAAQHGHYDVSEMLLQHQS 139
           KG   +H A      + ++ +L   G   N  +     P+  AA  G  +   MLL H  
Sbjct: 22  KGSSAVHEAIKVNNTDILRYLLTVPGLECNAVNASQKTPVMEAASRGRIECLTMLLDHGC 201

Query: 140 NPCMVDNSGKTPLDLACEFGRVGVVQLLLSSNM--CAALLEPRPG--DTTDPNGTSPLHL 195
           N    +  GKT +   C     G V++    +M  C  L+    G  +  D  GTSPLHL
Sbjct: 202 NTEGENIRGKTAMH-HCLLSCGGFVEI---EDMVTCMDLVYKAGGNINAQDWFGTSPLHL 369

Query: 196 A 196
           A
Sbjct: 370 A 372
>14754
          Length = 564

 Score = 41.2 bits (95), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 17/63 (26%), Positives = 34/63 (53%)
 Frame = +1

Query: 546 KPANLAVWLSMIGLAQYYKVLVDNGYENIDFITDITWEDLQEIGITKLGHQKKLMLAVRK 605
           KP ++   ++ IGL    KV +DNG++ ++   ++   DL  +GI +   + K++ A   
Sbjct: 124 KPRSVEDLMARIGLEHLTKVFMDNGFDTLEIFAEVDEGDLNTLGILQAEQRAKVLTAAEL 303

Query: 606 LAE 608
           L +
Sbjct: 304 LLD 312
>30978
          Length = 566

 Score = 40.8 bits (94), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 25/79 (31%), Positives = 40/79 (50%), Gaps = 2/79 (2%)
 Frame = -2

Query: 144 VDNSGKTPLDLACEFGRVGVVQLLLSSNMCAALLEPRPGDTTDPNGTSPLHLAAKNGHID 203
           +D +G TPL  A   G +  +Q+LLS   C   ++ + GDT        LH AA   H++
Sbjct: 484 LDKAGSTPLHWAGHGGHMDCLQVLLSEPKCEVNVQNKLGDTA-------LHSAAWKNHVE 326

Query: 204 IIRLLLQAG--IDINRQTK 220
            +++LL  G  +D+    K
Sbjct: 325 AVKMLLGKGARVDLRNNEK 269

 Score = 35.0 bits (79), Expect = 0.22,   Method: Compositional matrix adjust.
 Identities = 25/92 (27%), Positives = 44/92 (47%), Gaps = 1/92 (1%)
 Frame = -2

Query: 64  LISLLLEAQAAVDIKDNKGMRPLHYAAWQGRKEPMKLVLKA-GSAVNVPSDEGHIPLHLA 122
            ++  L  + +V+  D  G  PLH+A   G  + ++++L      VNV +  G   LH A
Sbjct: 526 FLTECLSNRVSVNGLDKAGSTPLHWAGHGGHMDCLQVLLSEPKCEVNVQNKLGDTALHSA 347

Query: 123 AQHGHYDVSEMLLQHQSNPCMVDNSGKTPLDL 154
           A   H +  +MLL   +   + +N  K  ++L
Sbjct: 346 AWKNHVEAVKMLLGKGARVDLRNNEKKLAVEL 251
>13622
          Length = 1144

 Score = 40.4 bits (93), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 24/64 (37%), Positives = 36/64 (56%), Gaps = 2/64 (3%)
 Frame = +1

Query: 545 HKPANLAVWLSMIGLAQYYKVLVDNGYENIDFITDITW--EDLQEIGITKLGHQKKLMLA 602
           HK  +LA   S +GL +Y  +      + IDF T +T   EDL+E+GI   G ++K+ML 
Sbjct: 508 HK-TDLAELFSKLGLGKYIDIFQQ---QEIDFSTFLTLNEEDLKELGIGTFGARRKMMLV 675

Query: 603 VRKL 606
           +  L
Sbjct: 676 IADL 687
>02351
          Length = 939

 Score = 40.0 bits (92), Expect = 0.007,   Method: Composition-based stats.
 Identities = 34/101 (33%), Positives = 48/101 (47%)
 Frame = +3

Query: 5   QELVQAVKAEDVGTAQRLLQRPRPGKAKLLGSTKKINVNFQDPDGFSALHHAALNGNTEL 64
           Q+L+ A+  ED+     +L     G A    ++  IN  +   DG +ALH AA  GN   
Sbjct: 363 QQLIDALVREDIRNIIIIL-----GHA----ASDDINSPYGKDDGRTALHIAAALGNVVY 515

Query: 65  ISLLLEAQAAVDIKDNKGMRPLHYAAWQGRKEPMKLVLKAG 105
           + LLL   A V + D++G   L YA   G  E   L+  AG
Sbjct: 516 VQLLLWYCANVKVVDHEGRNALWYARTSGSVECTDLLAAAG 638

 Score = 35.4 bits (80), Expect = 0.18,   Method: Compositional matrix adjust.
 Identities = 28/101 (27%), Positives = 47/101 (46%), Gaps = 6/101 (5%)
 Frame = +3

Query: 94  RKEPMKLVLKAGSA----VNVP--SDEGHIPLHLAAQHGHYDVSEMLLQHQSNPCMVDNS 147
           R++   +++  G A    +N P   D+G   LH+AA  G+    ++LL + +N  +VD+ 
Sbjct: 387 REDIRNIIIILGHAASDDINSPYGKDDGRTALHIAAALGNVVYVQLLLWYCANVKVVDHE 566

Query: 148 GKTPLDLACEFGRVGVVQLLLSSNMCAALLEPRPGDTTDPN 188
           G+  L  A   G V    LL ++        PR   +  PN
Sbjct: 567 GRNALWYARTSGSVECTDLLAAAGCPDTATLPRRRGSLQPN 689
>20121
          Length = 454

 Score = 39.7 bits (91), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 21/60 (35%), Positives = 34/60 (56%), Gaps = 1/60 (1%)
 Frame = -1

Query: 183 DTTDPNGTSPLHLAAKNGHIDIIRLLLQAGIDINRQTK-SGTALHEAALCGKTEVVRLLL 241
           +T DP G + LHL+   GH++  R+LL+ G +   +     + LHE    G  E+V+L+L
Sbjct: 268 ETKDPRGRTALHLSVSLGHLESTRVLLRHGAEAGTENNGCWSVLHEGVCSGDPELVQLIL 89

 Score = 30.0 bits (66), Expect = 7.3,   Method: Compositional matrix adjust.
 Identities = 22/72 (30%), Positives = 37/72 (51%)
 Frame = -1

Query: 32  KLLGSTKKINVNFQDPDGFSALHHAALNGNTELISLLLEAQAAVDIKDNKGMRPLHYAAW 91
           +LLG  K+ ++  +DP G +ALH +   G+ E   +LL   A    ++N     LH    
Sbjct: 298 RLLG-LKEHDIETKDPRGRTALHLSVSLGHLESTRVLLRHGAEAGTENNGCWSVLHEGVC 122

Query: 92  QGRKEPMKLVLK 103
            G  E ++L+L+
Sbjct: 121 SGDPELVQLILQ 86
>30217
          Length = 412

 Score = 38.5 bits (88), Expect = 0.022,   Method: Composition-based stats.
 Identities = 20/60 (33%), Positives = 36/60 (60%), Gaps = 3/60 (5%)
 Frame = -3

Query: 112 SDEGHIPLHLAAQHGHYDVSEMLLQHQSNPCMV---DNSGKTPLDLACEFGRVGVVQLLL 168
           +D+G  PLHLA   G+ DV   L++   +PC++   ++  +TPL LA    +  ++++LL
Sbjct: 215 NDDGDTPLHLACISGYVDVVAALIRMAPHPCLLNIQNDVAQTPLHLAALTAQPTILRMLL 36

 Score = 37.0 bits (84), Expect = 0.054,   Method: Composition-based stats.
 Identities = 26/72 (36%), Positives = 36/72 (50%), Gaps = 2/72 (2%)
 Frame = -3

Query: 145 DNSGKTPLDLACEFGRVGVVQLLLSSNMCAALLEPRPG--DTTDPNGTSPLHLAAKNGHI 202
           ++ G TPL LAC  G V VV  L+        + P P   +  +    +PLHLAA     
Sbjct: 215 NDDGDTPLHLACISGYVDVVAALIR-------MAPHPCLLNIQNDVAQTPLHLAALTAQP 57

Query: 203 DIIRLLLQAGID 214
            I+R+LL AG +
Sbjct: 56  TILRMLLLAGAE 21

 Score = 29.6 bits (65), Expect = 8.8,   Method: Composition-based stats.
 Identities = 19/71 (26%), Positives = 33/71 (46%), Gaps = 3/71 (4%)
 Frame = -3

Query: 78  KDNKGMRPLHYAAWQGRKEPMKLVLKAGS---AVNVPSDEGHIPLHLAAQHGHYDVSEML 134
           +++ G  PLH A   G  + +  +++       +N+ +D    PLHLAA      +  ML
Sbjct: 218 QNDDGDTPLHLACISGYVDVVAALIRMAPHPCLLNIQNDVAQTPLHLAALTAQPTILRML 39

Query: 135 LQHQSNPCMVD 145
           L   + P + D
Sbjct: 38  LLAGAEPTVRD 6
>33484
          Length = 436

 Score = 38.1 bits (87), Expect = 0.029,   Method: Compositional matrix adjust.
 Identities = 26/64 (40%), Positives = 35/64 (54%), Gaps = 2/64 (3%)
 Frame = -2

Query: 148 GKTPLDLACEFGRVGVVQLLLSSNMCAALLEPR--PGDTTDPNGTSPLHLAAKNGHIDII 205
           G++ L LAC  G   + Q+LL+ N   A +E R   GD T      PL  AA  G +DI+
Sbjct: 177 GESLLSLACSAGYYELAQVLLAMN---ANVEDRGIKGDCT------PLMEAASGGFVDIV 25

Query: 206 RLLL 209
           RLL+
Sbjct: 24  RLLI 13

 Score = 32.3 bits (72), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 21/61 (34%), Positives = 35/61 (57%), Gaps = 4/61 (6%)
 Frame = -2

Query: 112 SDEGHIPLHLAAQHGHYDVSEMLLQHQSNPCMVDNSG----KTPLDLACEFGRVGVVQLL 167
           ++EG   L LA   G+Y+++++LL   +N   V++ G     TPL  A   G V +V+LL
Sbjct: 186 TEEGESLLSLACSAGYYELAQVLLAMNAN---VEDRGIKGDCTPLMEAASGGFVDIVRLL 16

Query: 168 L 168
           +
Sbjct: 15  I 13

 Score = 31.2 bits (69), Expect = 2.9,   Method: Compositional matrix adjust.
 Identities = 22/61 (36%), Positives = 34/61 (55%), Gaps = 2/61 (3%)
 Frame = -2

Query: 183 DTTDPNGTSPLHLAAKNGHIDIIRLLLQAGIDINRQTKSG--TALHEAALCGKTEVVRLL 240
           DTT+  G S L LA   G+ ++ ++LL    ++  +   G  T L EAA  G  ++VRLL
Sbjct: 192 DTTE-EGESLLSLACSAGYYELAQVLLAMNANVEDRGIKGDCTPLMEAASGGFVDIVRLL 16

Query: 241 L 241
           +
Sbjct: 15  I 13
>22305
          Length = 426

 Score = 37.7 bits (86), Expect = 0.036,   Method: Composition-based stats.
 Identities = 20/65 (30%), Positives = 37/65 (56%)
 Frame = -3

Query: 63  ELISLLLEAQAAVDIKDNKGMRPLHYAAWQGRKEPMKLVLKAGSAVNVPSDEGHIPLHLA 122
           ++ + LLE   + + +++ G+ PLH A      E  +++L+ G+  NVP +   +PL  A
Sbjct: 343 DITTALLERGCSANERNHWGILPLHEALCWENVEVGRVLLQYGADPNVPCETNVVPLTFA 164

Query: 123 AQHGH 127
           A+ GH
Sbjct: 163 ARTGH 149
>07218
          Length = 1715

 Score = 37.4 bits (85), Expect = 0.049,   Method: Compositional matrix adjust.
 Identities = 23/60 (38%), Positives = 30/60 (50%), Gaps = 3/60 (5%)
 Frame = +1

Query: 481 VSQWLATFQLQLYAPNFTSA---GYDLPTISRMTPEDLTAIGVTKPGHRKKITAEISGLN 537
           V  WL +  L  Y  NF S    G +L ++ R    DL  +GVTK GH K+I   I  L+
Sbjct: 214 VGAWLESLSLGEYRANFISHEIRGAELLSLER---RDLKDLGVTKVGHLKRIQQAIKELH 384

 Score = 34.3 bits (77), Expect = 0.39,   Method: Compositional matrix adjust.
 Identities = 16/71 (22%), Positives = 37/71 (52%)
 Frame = +1

Query: 536 LNIPDWLPEHKPANLAVWLSMIGLAQYYKVLVDNGYENIDFITDITWEDLQEIGITKLGH 595
            +I  W  +     +  WL  + L +Y    + +     + ++ +   DL+++G+TK+GH
Sbjct: 184 FDIRSWTTD----EVGAWLESLSLGEYRANFISHEIRGAELLS-LERRDLKDLGVTKVGH 348

Query: 596 QKKLMLAVRKL 606
            K++  A+++L
Sbjct: 349 LKRIQQAIKEL 381
>27252
          Length = 378

 Score = 36.6 bits (83), Expect = 0.067,   Method: Compositional matrix adjust.
 Identities = 20/50 (40%), Positives = 27/50 (54%)
 Frame = +2

Query: 296 YDLTSLNVKAGDIITVLEQHPDGRWKGCIHDNRTGNDRVGYFPSSLGEAI 345
           YD T L +K G+ I VL  + DG+W+G I      N R G FP +  E +
Sbjct: 158 YDRTQLKLKQGETIKVLAINIDGQWEGEI------NGRTGKFPFTHVEFL 289
>05396
          Length = 1865

 Score = 35.8 bits (81), Expect = 0.14,   Method: Composition-based stats.
 Identities = 26/89 (29%), Positives = 48/89 (53%), Gaps = 2/89 (2%)
 Frame = +3

Query: 193  LHLAAKNGHIDIIRLLLQAGIDINRQTKSG-TALHEAALCGKTEVVRLLLDS-GINAQVR 250
            L  +A NG +  IR    +G+D+++    G TALH A+  G+ +VV  LLD    +  + 
Sbjct: 1296 LLFSAYNGDVTAIRRCALSGMDMSQPDYDGRTALHVASAEGQLQVVEFLLDRCKCSPFLV 1475

Query: 251  NTYSQTALDIVHQFTTSQASKEIKQLLRE 279
            + +  T LD   +F   +A++ +K+ + +
Sbjct: 1476 DRWGFTPLDDAVRFEKHEAAELLKERMMQ 1562
>03590
          Length = 1068

 Score = 35.4 bits (80), Expect = 0.15,   Method: Compositional matrix adjust.
 Identities = 27/83 (32%), Positives = 38/83 (45%), Gaps = 5/83 (6%)
 Frame = +3

Query: 59  NGNTELISLLLEAQAAVDIKDNKGMRPLHYAAWQGRKEPMKLVLKAGSA-----VNVPSD 113
           N +T L   LLE +A V  K++ G  P+H        +P++L+    +A     V+ P  
Sbjct: 813 NDSTALEEFLLEHKADVFAKNDDGYMPIHCVFVGCGPDPIELLSLLTAAMKDQQVDEPVL 992

Query: 114 EGHIPLHLAAQHGHYDVSEMLLQ 136
            G  PLH AA  G       LLQ
Sbjct: 993 SGFSPLHFAAARGATICCMHLLQ 1061
>13900
          Length = 751

 Score = 33.5 bits (75), Expect = 0.57,   Method: Composition-based stats.
 Identities = 17/41 (41%), Positives = 25/41 (60%)
 Frame = +1

Query: 115 GHIPLHLAAQHGHYDVSEMLLQHQSNPCMVDNSGKTPLDLA 155
           G  PLHLA +   +  ++ LL+  S+P + D SG TPL +A
Sbjct: 280 GQSPLHLAVRVNDFHKAKKLLKLGSDPLLPDFSGITPLRMA 402
>21751
          Length = 643

 Score = 33.5 bits (75), Expect = 0.70,   Method: Composition-based stats.
 Identities = 13/27 (48%), Positives = 20/27 (74%)
 Frame = +3

Query: 191 SPLHLAAKNGHIDIIRLLLQAGIDINR 217
           SP+H A +N  +D+I LL++ G D+NR
Sbjct: 186 SPIHQAVRNLDLDMINLLIEFGADLNR 266

 Score = 31.2 bits (69), Expect = 2.9,   Method: Composition-based stats.
 Identities = 17/56 (30%), Positives = 32/56 (57%), Gaps = 2/56 (3%)
 Frame = +3

Query: 191 SPLHLAAKNGHIDIIRLLLQAGIDINRQTKSG--TALHEAALCGKTEVVRLLLDSG 244
           SPLH+A    ++ + RLLL+ G D+N+       + +H+A      +++ LL++ G
Sbjct: 84  SPLHVAILRKNVHLGRLLLEHGEDVNQTFNDSLESPIHQAVRNLDLDMINLLIEFG 251

 Score = 30.8 bits (68), Expect = 4.4,   Method: Composition-based stats.
 Identities = 24/77 (31%), Positives = 36/77 (46%), Gaps = 1/77 (1%)
 Frame = +3

Query: 51  SALHHAALNGNTELISLLLEAQAAVDIKDNKGMR-PLHYAAWQGRKEPMKLVLKAGSAVN 109
           S LH A L  N  L  LLLE    V+   N  +  P+H A      + + L+++ G+ +N
Sbjct: 84  SPLHVAILRKNVHLGRLLLEHGEDVNQTFNDSLESPIHQAVRNLDLDMINLLIEFGADLN 263

Query: 110 VPSDEGHIPLHLAAQHG 126
            P+     P  + A HG
Sbjct: 264 RPNF*TTYPGRVVADHG 314
>28491
          Length = 394

 Score = 33.1 bits (74), Expect = 0.74,   Method: Composition-based stats.
 Identities = 26/76 (34%), Positives = 40/76 (52%), Gaps = 6/76 (7%)
 Frame = +3

Query: 172 MCAALLEPRPGDTTDPNGTSPLHLA---AKNGH-IDIIRLLLQAGIDINRQTKSG--TAL 225
           + A L E R  +  + +  +PL  A   AK  H I +I+LLL+ G D+N Q  +G  + +
Sbjct: 147 LSALLSEARSMEIRNEHSCTPLLYASRYAKGDHGIYLIKLLLRQGSDVNAQDDAGMTSLM 326

Query: 226 HEAALCGKTEVVRLLL 241
           H  A  G  + VR L+
Sbjct: 327 HVIAEGGSVDAVRPLI 374
>28539
          Length = 513

 Score = 33.1 bits (74), Expect = 0.93,   Method: Compositional matrix adjust.
 Identities = 24/74 (32%), Positives = 36/74 (48%), Gaps = 3/74 (4%)
 Frame = -2

Query: 550 LAVWLSMIGLAQYYKVLVDNGYENIDFITDITWED---LQEIGITKLGHQKKLMLAVRKL 606
           L  WL   GL  YY+  V +G   +  I  ++  D     E+ IT  GH+++   AV  L
Sbjct: 506 LVCWLRENGLDHYYEGFVQSGRVLLMDIAQLSLPDEDVYDELEITLPGHKRRFERAVHAL 327

Query: 607 AELQKAEYSKYEGG 620
            + Q +E S+ E G
Sbjct: 326 RKRQXSEDSQREEG 285
>36917
          Length = 443

 Score = 32.3 bits (72), Expect = 1.4,   Method: Composition-based stats.
 Identities = 16/40 (40%), Positives = 24/40 (60%), Gaps = 1/40 (2%)
 Frame = -1

Query: 190 TSPLHLAAKNGHIDIIRLLLQAGIDINRQT-KSGTALHEA 228
           T  LH+AA NG+I++   LL   + ++RQ  +S   LH A
Sbjct: 122 TQQLHIAAANGYIEVAEFLLDNHVSVDRQDHESWQPLHAA 3
>27108
          Length = 449

 Score = 30.4 bits (67), Expect = 5.2,   Method: Composition-based stats.
 Identities = 25/90 (27%), Positives = 43/90 (47%), Gaps = 21/90 (23%)
 Frame = -3

Query: 183 DTTDPNGTSPLHLAAKNGHIDIIRLLL------------QAG--------IDINRQTKSG 222
           ++ D  G + LH A  +GH++  R LL            Q+G        +D++   + G
Sbjct: 303 NSQDYAGWTALHEACNHGHLECARALLKFVPSATLDSFFQSGKNRGKVRKVDMHLANQEG 124

Query: 223 -TALHEAALCGKTEVVRLLLDSGINAQVRN 251
            TALH+A       VV+LLL  G ++ +++
Sbjct: 123 ITALHDAVSMNHVSVVKLLLKYGGSSLLKD 34
>36879
          Length = 583

 Score = 30.4 bits (67), Expect = 5.4,   Method: Composition-based stats.
 Identities = 15/29 (51%), Positives = 18/29 (62%)
 Frame = -3

Query: 186 DPNGTSPLHLAAKNGHIDIIRLLLQAGID 214
           D  G +PL LAAKNG   +   LL+AG D
Sbjct: 473 DDVGETPLMLAAKNGQDYVCERLLEAGAD 387
>18050
          Length = 448

 Score = 30.0 bits (66), Expect = 6.2,   Method: Compositional matrix adjust.
 Identities = 15/45 (33%), Positives = 25/45 (55%)
 Frame = +3

Query: 301 LNVKAGDIITVLEQHPDGRWKGCIHDNRTGNDRVGYFPSSLGEAI 345
           L ++ GD++ V  + PDG ++G     R  +  VG+FP S  E +
Sbjct: 66  LQLELGDVVNVSRKLPDGWYQG----ERIRDGAVGWFPGSYTEEL 188
>18216
          Length = 472

 Score = 30.0 bits (66), Expect = 6.6,   Method: Composition-based stats.
 Identities = 16/41 (39%), Positives = 24/41 (58%), Gaps = 3/41 (7%)
 Frame = +2

Query: 183 DTTDPNGTSPLHLAAKNGHIDIIRLLLQAGID---INRQTK 220
           +  DP G +    AA  GH+ +++ LL+AG D   INRQ +
Sbjct: 287 NAVDPFGWTAAMSAAFEGHLAVVQTLLEAGADLSVINRQGR 409
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|82949228|ref|XP_484214.3| PREDICTED: hypothetical
protein LOC208440 isoform 1 [Mus musculus]
         (1556 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

36633                                                                  97   5e-20
01835                                                                  32   2.9  
02291                                                                  31   4.1  
03756                                                                  31   4.9  
14096                                                                  30   6.2  
>36633
          Length = 355

 Score = 97.1 bits (240), Expect = 5e-20,   Method: Compositional matrix adjust.
 Identities = 48/82 (58%), Positives = 62/82 (75%), Gaps = 1/82 (1%)
 Frame = +2

Query: 669 SNQPPGRGVLSMHGLTYGVIRVDSEEKLSVLTVQDVGLVMPGAIMCSVKPDGIPQLCRTD 728
           S+   GRG+LSM GL++GV+RVD+E  L+ LT+QD G VMPGA+M  +K DG P +C+TD
Sbjct: 8   SSSATGRGILSMQGLSHGVVRVDNENSLTSLTLQDCGQVMPGALMVVIKLDGSPTVCKTD 187

Query: 729 EIGELCVCAVAT-GTSYYGLSG 749
           E+G  CVC  AT GTSY+GL G
Sbjct: 188 EVGS-CVCVRATRGTSYWGLQG 250

 Score = 39.3 bits (90), Expect = 0.012,   Method: Compositional matrix adjust.
 Identities = 23/65 (35%), Positives = 35/65 (53%), Gaps = 7/65 (10%)
 Frame = +1

Query: 718 PDGIPQLCRT------DEIGELCVCAVATGTSYYGLSGMTKN-TFEVFPMTSSGAPISEY 770
           PDG  Q  R          GELCVC+  TG    G +G + + TF+V P+++ G P+ + 
Sbjct: 136 PDGGDQAGRQPHGVQDGRGGELCVCSGYTGHQLLGPAGQSPSPTFQVQPLSADGRPLGDK 315

Query: 771 PFIRT 775
            ++RT
Sbjct: 316 LYVRT 330
>01835
          Length = 967

 Score = 31.6 bits (70), Expect = 2.9,   Method: Composition-based stats.
 Identities = 15/46 (32%), Positives = 20/46 (43%)
 Frame = +1

Query: 290 PDPNQPKPEGAQMLATRGEQLGVVTNWPPSLEAALQRWGTISPKAP 335
           P P QP+P     + + G  L   T WP S      RW +  P +P
Sbjct: 529 PGPLQPRPSNEHWM-S*GSNLKTCTRWPFSWTIPWSRWNSKGPPSP 663
>02291
          Length = 3161

 Score = 30.8 bits (68), Expect = 4.1,   Method: Compositional matrix adjust.
 Identities = 32/129 (24%), Positives = 51/129 (39%), Gaps = 20/129 (15%)
 Frame = -1

Query: 1046 GCLYAGCVPITVRPPHPQNIATTLPTVKMIVEVSRSACLM---TTQLICKLLRSR----- 1097
            GC+YAG +   +         T  P     V  S  A ++    +Q + K+L+ R     
Sbjct: 3161 GCIYAGGLATGI-------YTTNSPEACEFVAASSQANVIVAENSQQLKKILQVRHNLPH 3003

Query: 1098 -----------EAAAAVDVRTWPLILDT-DDLPKKRPAQIYKPSNPDTLAYLDFSVSTTG 1145
                       + A A DV +W   +   DD+P     +  K  +P+    L ++  TTG
Sbjct: 3002 LKAIVQYTGQVDEAHAKDVLSWEQFMKAGDDVPDSVLDERIKALSPNKCCVLIYTSGTTG 2823

Query: 1146 MLAGVKMSH 1154
               GV +SH
Sbjct: 2822 TPKGVMLSH 2796
>03756
          Length = 992

 Score = 30.8 bits (68), Expect = 4.9,   Method: Compositional matrix adjust.
 Identities = 23/81 (28%), Positives = 34/81 (41%), Gaps = 16/81 (19%)
 Frame = +2

Query: 1106 RTWPLILDTDDLPKKRPAQIYK----------------PSNPDTLAYLDFSVSTTGMLAG 1149
            +TWP   D  DL  +R  ++                  P  PD LA L ++  TTG   G
Sbjct: 602  KTWPQ--DIRDLANERKVELLTFKEIESIGTKDTRDPIPPKPDDLATLCYTSGTTGDPKG 775

Query: 1150 VKMSHAATSAFCRSIKLQCEL 1170
            V ++HA       S+ LQ ++
Sbjct: 776  VMLTHANFLIMLSSVYLQAKV 838
>14096
          Length = 983

 Score = 30.4 bits (67), Expect = 6.2,   Method: Compositional matrix adjust.
 Identities = 17/65 (26%), Positives = 26/65 (40%)
 Frame = -3

Query: 330 ISPKAPCLTTMDTNGKPLYILTYGKLWTRSMKVAYNILHKLGTKQEPMVRPGDRVALVFP 389
             P  P  T     GKP+ +  +  LW + + +    L     K   +   G+R+A V  
Sbjct: 342 FKPSRPQRTKSRLRGKPVLVFVFRTLWNKLIXMHMTCLLCSWAKSARVTEKGERIACVTV 163

Query: 390 NNDPA 394
            N PA
Sbjct: 162 FNYPA 148
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|209862776|ref|NP_705817.2| anoctamin 2 [Mus musculus]
         (1002 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

30769                                                                  96   7e-20
08265                                                                  33   0.57 
11901                                                                  31   2.4  
22170                                                                  30   4.6  
>30769
          Length = 460

 Score = 95.9 bits (237), Expect = 7e-20,   Method: Composition-based stats.
 Identities = 56/172 (32%), Positives = 86/172 (50%), Gaps = 2/172 (1%)
 Frame = -3

Query: 390 TIEEDIPSKEMCDHQNA--FTMCPLCDKSCDYWNLSSACGTARASHLFDNPATVFFSIFM 447
           T  +D  S ++C+   +  F MCP+CDK C YW L  +C  +  ++LFDN ATV F+ FM
Sbjct: 458 TFSDDDTSNDICNKTGSGQFVMCPVCDKRCPYWELYRSCTYSTITYLFDNEATVIFAAFM 279

Query: 448 ALWATMFLENWKRLQMRLGYFWDLTGIXXXXXXXXXXXXXXYETKVREKLLKESGKSAVQ 507
           ALWA  F+E WKR    + Y WD+                       E+ ++   +++V+
Sbjct: 278 ALWAEFFIEMWKRRTAEIEYDWDVADFE------------------EEETVRPEFEASVK 153

Query: 508 KLEANSPEDDEDDEDKLTWKDRFPGYLMNFASILFMIALTFSIVFGVIVYRI 559
           K   N     E  E  L +  R   YL +   ++ M+ +  + VFGVI+YR+
Sbjct: 152 KRRTNPVNMSE--EPYLGFLSRVIRYLSSLTVVVVMLCVVLAAVFGVIIYRM 3
>08265
          Length = 494

 Score = 33.1 bits (74), Expect = 0.57,   Method: Composition-based stats.
 Identities = 17/59 (28%), Positives = 30/59 (50%), Gaps = 1/59 (1%)
 Frame = +2

Query: 850 LSFFNVSQLKEGTQPENSQFDQEVQFCRFKDYRE-PPWAPNPYEFSKQYWSVLSARLAF 907
           L++F+    K+ T   NS  + +  FC+ +D+R  P     PYE S+  + +L+    F
Sbjct: 26  LTYFDTHAHKKNTSYTNSNSNSKTLFCKDEDFRHMPSLTICPYEMSQSNYYILAHSHTF 202
>11901
          Length = 656

 Score = 31.2 bits (69), Expect = 2.4,   Method: Composition-based stats.
 Identities = 21/66 (31%), Positives = 29/66 (43%), Gaps = 2/66 (3%)
 Frame = -1

Query: 388 CATIEEDIPSKEMCDHQNAFTMCPLCDKSCDYWNLSSACGTARASHLFDNPATVFFSIF- 446
           C  I    P+      + A T CPLC  + D W  +  CG  RA+ L +      FS F 
Sbjct: 506 CCRINXMGPTLSDPSQRRARTSCPLC--AMDKWVTARFCGETRATALLNR-----FSSF* 348

Query: 447 -MALWA 451
             A+W+
Sbjct: 347 PSAIWS 330
>22170
          Length = 495

 Score = 30.0 bits (66), Expect = 4.6,   Method: Composition-based stats.
 Identities = 12/35 (34%), Positives = 21/35 (60%)
 Frame = +1

Query: 526 WKDRFPGYLMNFASILFMIALTFSIVFGVIVYRIT 560
           W     G L +F S+L +I++ F ++ GV+  R+T
Sbjct: 61  WHPSLSGPLFSFGSLLTVISILFVLLCGVVTARVT 165
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|26986557|ref|NP_758469.1| eukaryotic translation
initiation factor 2B, subunit 5 epsilon [Mus musculus]
         (717 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

15705                                                                  96   7e-20
01971                                                                  42   0.001
00981                                                                  40   0.002
16948                                                                  35   0.094
02310                                                                  30   2.9  
25327                                                                  29   5.1  
27529                                                                  29   6.8  
14839                                                                  28   9.5  
>15705
          Length = 2141

 Score = 95.5 bits (236), Expect = 7e-20,   Method: Compositional matrix adjust.
 Identities = 56/170 (32%), Positives = 97/170 (57%), Gaps = 5/170 (2%)
 Frame = +1

Query: 542 QLDDIRVFQNEVLGTLQRGREENISCENLVLEINSLKHAYNISLKEVMQVLTLVVLEFPL 601
           ++D+   F +E+  TL+R +EENI  +NL+LE+NSLKHA+NI +K+V Q +  V++E PL
Sbjct: 592 EVDEYGSFYSELTATLKRAKEENIGLDNLILEVNSLKHAFNIDIKDVHQAVVKVLVEMPL 771

Query: 602 QQVDGLLDP----NRYCALLLPLLKAWSPVLRNYIKRAADHLEALAAIEDFFLEHETLVT 657
                 L+P          +L  +++   +L++Y K      + L  +EDF +E E +++
Sbjct: 772 N-----LNPKAQGKELITAVLRHVESHKGLLKHYTKNKEAQWDCLHTLEDFAVESERMLS 936

Query: 658 SMAKVLMAFYQLEILAEETILSWFSQRDTTDEGQQLRK-NQQLQRFIQWL 706
            + KV+   Y  +I+ E  I++W       DE ++  K  +Q+Q F+ WL
Sbjct: 937 VLGKVVQYLYDKDIIDERIIIAWHHTEAEEDEEEEHGKIRRQMQAFVTWL 1086

 Score = 95.1 bits (235), Expect = 8e-20,   Method: Compositional matrix adjust.
 Identities = 50/123 (40%), Positives = 68/123 (55%)
 Frame = +3

Query: 336 HNIYRGPEVSLGHGSVLEENVLLGAGTVIGSNCSITNSVIGPNCHIGDNVVLDQAYLWQG 395
            N+Y  P VSL   + L+ NV++G GT I +   I +SVIG NC IG NV +   YLW  
Sbjct: 3   RNVYISPHVSLASSAELKNNVVVGKGTTIDAKTEIQSSVIGENCIIGANVTMRNCYLWGS 182

Query: 396 VRVAAGAQIHQSLLCDRAEVKERVKLKPYCVLTSQVVVGPDITLPEGSVISLHPPDAEED 455
           VR+  G  +   ++CD   V     ++P+ VL+  V VGPDITLPE   +   P   E  
Sbjct: 183 VRIEEGCVLSDCIVCDGVTVFANTTVQPHSVLSWNVKVGPDITLPEAVRLQDTPQKDEFA 362

Query: 456 EDD 458
           +DD
Sbjct: 363 DDD 371
>01971
          Length = 1169

 Score = 41.6 bits (96), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 22/86 (25%), Positives = 49/86 (56%)
 Frame = +1

Query: 621 LKAWSPVLRNYIKRAADHLEALAAIEDFFLEHETLVTSMAKVLMAFYQLEILAEETILSW 680
           L+ ++ +L    K A   L  +  ++++  E+   + S  K+++  Y+ ++L+EETIL W
Sbjct: 16  LRMYTSLLATTAKSARAELALMLRVQEYCYENMNFLKSFQKIIIMLYKTDVLSEETILRW 195

Query: 681 FSQRDTTDEGQQLRKNQQLQRFIQWL 706
           + Q   + +G+ +  + Q++ F+ WL
Sbjct: 196 YKQAH-SPKGKSVFLD-QMKTFVDWL 267
>00981
          Length = 1528

 Score = 40.4 bits (93), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 19/81 (23%), Positives = 37/81 (45%)
 Frame = +2

Query: 342 PEVSLGHGSVLEENVLLGAGTVIGSNCSITNSVIGPNCHIGDNVVLDQAYLWQGVRVAAG 401
           P V +   + +  +  +G  + +G    +  SV+G NC + D   +  + L  GV V   
Sbjct: 605 PSVKVPRTTQMGPDCFIGDNSRVGEKMVMKKSVVGANCVLHDKAKISNSILMDGVEVGES 784

Query: 402 AQIHQSLLCDRAEVKERVKLK 422
             +  S+LC    + E+ ++K
Sbjct: 785 CLVMNSILCSGVVLAEKCEIK 847
>16948
          Length = 1465

 Score = 35.0 bits (79), Expect = 0.094,   Method: Compositional matrix adjust.
 Identities = 22/60 (36%), Positives = 34/60 (56%), Gaps = 4/60 (6%)
 Frame = +3

Query: 654 TLVTSMAKVLMAFYQLEILAEETILSW---FSQRDTTDE-GQQLRKNQQLQRFIQWLREA 709
            L+  +  VL  FY L+IL EE I+ W    S++  + E  QQ+R  ++ + FI WL +A
Sbjct: 12  ALMPRVPHVLKTFYDLDILDEEIIIDWAKKMSKKYVSKEIAQQMR--EKAKPFIDWLEQA 185
>02310
          Length = 1065

 Score = 30.4 bits (67), Expect = 2.9,   Method: Compositional matrix adjust.
 Identities = 24/71 (33%), Positives = 35/71 (49%)
 Frame = +2

Query: 92  CWKAAQIKEHLQKSKWCHPTSPNVVRIITSELYRSLGDVLRDVDAKALVRSDFLLIYGDV 151
           C+ A Q+K   +  KW    SP  V   +    RS+ D  R ++ + +VR   L  YGD+
Sbjct: 836 CY*AFQVKMRKRVVKWL-AYSPLRVLTHSDRWSRSVDD--RSINGEIIVR--ILHTYGDI 1000

Query: 152 ISNINICRALE 162
            SNI  C +L 
Sbjct: 1001CSNITNCASLS 1033
>25327
          Length = 480

 Score = 29.3 bits (64), Expect = 5.1,   Method: Composition-based stats.
 Identities = 24/82 (29%), Positives = 40/82 (48%), Gaps = 3/82 (3%)
 Frame = -3

Query: 249 SPQVAQLFTDNFDYQTRDDFV-RGILMNEEVLGNQIHLHVTTREYGARVSNLHMYSAVCA 307
           SP +   +T+N    +   FV + +++N+ V  + I+L   T+        LH Y+ VC 
Sbjct: 454 SPHIIISYTNNIP*ASYC*FVLKYLILNKTVSTHTINLFNATQNL-----KLHTYTYVCI 290

Query: 308 DVIRRWVYPLTP--EVNFTDST 327
             I    + LTP   +N TD+T
Sbjct: 289 I*IHSCTHTLTPNDRINVTDTT 224
>27529
          Length = 788

 Score = 28.9 bits (63), Expect = 6.8,   Method: Compositional matrix adjust.
 Identities = 15/52 (28%), Positives = 27/52 (51%), Gaps = 1/52 (1%)
 Frame = -1

Query: 195 DNVVMAVD-SATNRVLHFQKTQGLRRFSFPLSLFQGSGDGVEIRYDLLDCHI 245
           D+++ AV    TNR  HF  +  + + S    L + + + + IRYD L  ++
Sbjct: 644 DDIITAVKLVKTNRQCHFSVSSNISKISESPLLNKDNNNSITIRYDTLQTYL 489
>14839
          Length = 340

 Score = 28.5 bits (62), Expect = 9.5,   Method: Composition-based stats.
 Identities = 21/77 (27%), Positives = 36/77 (46%), Gaps = 4/77 (5%)
 Frame = +3

Query: 638 HLEALAAIEDFFLEHETLVTSMAKVLMAFYQLEILAEETILSWFSQRDTTDE----GQQL 693
            + AL A++ F   H      + +  +  Y  EI+ EE  L W  + +  DE    G+ L
Sbjct: 15  QVSALYAVQVFCHSHHFPKGMLLRFFVNLYDQEIIEEEAFLHW--KEEVNDEFPGKGKAL 188

Query: 694 RKNQQLQRFIQWLREAE 710
               Q+ +++ WL +AE
Sbjct: 189 F---QVNQWLTWLEQAE 230
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|29243896|ref|NP_808229.1| ubiquitin specific
peptidase 46 [Mus musculus]
         (366 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

11884                                                                  94   7e-20
08419                                                                  52   5e-07
04261                                                                  49   3e-06
35122                                                                  35   0.045
34092                                                                  30   1.9  
06607                                                                  28   4.1  
>11884
          Length = 952

 Score = 94.4 bits (233), Expect = 7e-20,   Method: Compositional matrix adjust.
 Identities = 56/198 (28%), Positives = 95/198 (47%), Gaps = 1/198 (0%)
 Frame = +3

Query: 166 TWVHEIFQGTLTNETRCLNCETVSSKDEDFLDLSVDVEQNTSITHCLRDFSNTETLCSEQ 225
           T +H++F G L ++ +CL C   S+  E F+DLS++++   ++   L  +   ETL +  
Sbjct: 6   TVIHQVFGGFLRSQVQCLKCGARSNTFEPFMDLSLNLKDVNTVEAALGKYVKPETLDAAN 185

Query: 226 KYYCETCCSKQEAQKRMRVKKLPMILALHLKRFKYMEQLHRYTKLSYRVVFPLELRLFNT 285
            Y C+ C  K +A+KR  + K+P +L + L RF +        K++  + FP +L +   
Sbjct: 186 AYDCQKCRKKTQARKRFSLHKIPNVLTIQLNRFGFTRAA---GKINKHIQFPEKLNVRQY 356

Query: 286 SSDAVNLDRMYDLVAVVVHCGSGPNRGHYITIVKSHG-FWLLFDDDIVEKIDAQAIEEFY 344
            S        Y L  V++H G   N GHY   V+S    W + +D  V ++ A  +   +
Sbjct: 357 MSRRQGDPEYYHLYGVLIHSGHHCNMGHYYCYVRSPANSWYIMNDSSVHQVSASRV---F 527

Query: 345 GLTSDISKNSESGYILFY 362
           G            Y+LFY
Sbjct: 528 G---------SQAYLLFY 554
>08419
          Length = 731

 Score = 51.6 bits (122), Expect = 5e-07,   Method: Compositional matrix adjust.
 Identities = 43/144 (29%), Positives = 70/144 (48%), Gaps = 14/144 (9%)
 Frame = +1

Query: 234 SKQEAQKRMRVKKLPMILALHLKRFKYMEQLHRYTKLSYRVVFPLE-LRLFNTSSDAV-- 290
           +  + Q+R  + +LP  L + L RF+Y  Q    TKL   V   L+ L L +   D V  
Sbjct: 97  TPSDIQRRCLLSQLPECLIIQLMRFQYNAQQGCSTKLRAPVSIRLKGLNLQDLMCDTVTQ 276

Query: 291 ---------NLDRMYDLVAVVVHCGS-GPNRGHYITI-VKSHGFWLLFDDDIVEKIDAQA 339
                    N  +MYDL  + +H G+   + GHYI+  + S   W  +DD+ V +++   
Sbjct: 277 REDCVSPGQNSSQMYDLYGLCLHIGADSTHHGHYISYSLASDSRWYRYDDEAVTEVNI-- 450

Query: 340 IEEFYGLTSDISKNSESGYILFYQ 363
             E+   T ++ +N+   YILFY+
Sbjct: 451 --EYELTTKEVRQNA---YILFYK 507
>04261
          Length = 1792

 Score = 49.3 bits (116), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 39/128 (30%), Positives = 63/128 (49%), Gaps = 4/128 (3%)
 Frame = +2

Query: 170 EIFQGTLTNETRCLNC----ETVSSKDEDFLDLSVDVEQNTSITHCLRDFSNTETLCSEQ 225
           E+ QGT     +CL+C    +T+       LD+  D   + S+   ++++  TE    E 
Sbjct: 266 EVVQGT-----KCLSCHGYVQTIIPLSNLILDIP-DKPLSPSLKDAVKNYFKTE----EI 415

Query: 226 KYYCETCCSKQEAQKRMRVKKLPMILALHLKRFKYMEQLHRYTKLSYRVVFPLELRLFNT 285
           +Y CE C    +A+   R KKLP IL L+LKRF+Y  ++ +  K       PL L  F +
Sbjct: 416 EYSCEFCHQHTKAELSSRFKKLPRILILYLKRFEYKGKMSKILK-------PLSLPAFIS 574

Query: 286 SSDAVNLD 293
             D  +++
Sbjct: 575 VQDHCDIN 598
>35122
          Length = 1031

 Score = 35.0 bits (79), Expect = 0.045,   Method: Compositional matrix adjust.
 Identities = 22/76 (28%), Positives = 30/76 (39%)
 Frame = -3

Query: 32  EHYFGLVNFGNTCYCNSVLQALYFCRPFRENVLAYKAQQKKKENLLTCLADLFHSIATQK 91
           E   GL N GNTCY N+ +Q L      R+ + +Y                      T  
Sbjct: 777 EMPAGLANLGNTCYMNATIQCLRAVPELRDALKSY----------------------TGN 664

Query: 92  KKVGVIPPKKFISRLR 107
             +GV PP + +S LR
Sbjct: 663 MTLGVPPPHQTLSLLR 616
>34092
          Length = 1009

 Score = 29.6 bits (65), Expect = 1.9,   Method: Compositional matrix adjust.
 Identities = 33/113 (29%), Positives = 53/113 (46%), Gaps = 13/113 (11%)
 Frame = -1

Query: 36  GLVNFG-NTCYCNSVLQALYFCRPFRENVLAYKAQQKKKENL-----LTCLADLFHSIAT 89
           GL N G N C+ N+VLQ L    P+    LA  A ++ +  +     L+ L++L   +  
Sbjct: 958 GLRNKGQNHCFMNAVLQCLSRS-PYLVPCLAVDAAKELEGTVSESLFLSTLSELMDLLTA 782

Query: 90  QKKKV--GVIPPKKF---ISRLRKE--NDLFDNYMQQDAHEFLNYLLNTIADI 135
           + + +   V+ P  F    S L K     +     QQDA EFL ++L+ +  I
Sbjct: 781 EPETLDSSVLDPTAFRHAASSLNKNLVAPVGQQQCQQDAAEFLMWMLDMVHRI 623
>06607
          Length = 723

 Score = 28.5 bits (62), Expect = 4.1,   Method: Compositional matrix adjust.
 Identities = 16/46 (34%), Positives = 24/46 (52%)
 Frame = +1

Query: 180 TRCLNCETVSSKDEDFLDLSVDVEQNTSITHCLRDFSNTETLCSEQ 225
           T CL C  +SS D   L +     +  +I  CL DFS   ++CS++
Sbjct: 322 TNCLRCIVISSSDGQVL-VRDSCSKRCNIBQCLSDFSKERSVCSDR 456
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|161484656|ref|NP_034353.2| FK506 binding protein 8
isoform b [Mus musculus]
         (402 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

00888                                                                  94   8e-20
03857                                                                  66   2e-11
26568                                                                  56   1e-10
13560                                                                  54   2e-07
23484                                                                  49   2e-06
00011                                                                  47   2e-05
32109                                                                  42   3e-04
01124                                                                  39   0.003
35348                                                                  34   0.14 
20302                                                                  32   0.47 
04645                                                                  31   1.1  
08670                                                                  31   1.1  
>00888
          Length = 970

 Score = 94.4 bits (233), Expect = 8e-20,   Method: Compositional matrix adjust.
 Identities = 63/218 (28%), Positives = 104/218 (47%), Gaps = 1/218 (0%)
 Frame = -3

Query: 142 VIQALDLSVPLMDVGETAMVTADSKYCYGPQGRSPY-IPPHAALCLEVTLKTAEDGPDLE 200
           +I  ++L+   M  GE   +T  SKY YG +G   + IP +A L   V +   E      
Sbjct: 950 IIAGIELATLKMKKGERDQLTVASKYAYGEEGCXRFNIPSNATLVYNVEMVNFEKAKQSW 771

Query: 201 MLSGQERVALANRKRECGNAHYQRADFVLAANSYDLAIKAITSNTKVDMTCXXXXXXXQL 260
            +   E++  +   +E G A +++  +  A  +Y+  I +   +    ++        QL
Sbjct: 770 EMDVGEKIEQSKIIKEKGTAAFKKGKYQRALTNYE-KIVSFLEHESTGLSDSELSDKHQL 594

Query: 261 KVKCLNNLAASQLKLDHYRAALRSCSQVLEHQPDNIKALFRKGKVLAQQGEYSEAIPILR 320
            V    N+A  QLKL  YR A  +C++VL    +N+KALFR+G+   +  +Y+EA     
Sbjct: 593 MVAAFLNIAMCQLKLLDYRQAEETCNKVLAMSTNNVKALFRRGQARLECADYTEAASDFS 414

Query: 321 AALKLEPSNKTIHAELSKLVKKRAAQRSTETALYRKML 358
             L+LEP NK    +    ++K+ A  + E ALY  M 
Sbjct: 413 KVLELEPGNKAAKNQHIVCLQKQKADYAKEKALYTNMF 300
>03857
          Length = 1696

 Score = 66.2 bits (160), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 73/277 (26%), Positives = 110/277 (39%), Gaps = 7/277 (2%)
 Frame = +1

Query: 89  NGLLRMKTLVPGPK-GSSRPLKGQVVTVH-LQMSLENGTRVQEEPELAFTLGDCDVIQAL 146
           NG     T VP P       + G+V+  H +   LEN  +  E P    ++ DC  + A 
Sbjct: 169 NGSQFFITTVPTPHLDGKHVVFGEVIAGHNVVRELENVDKDGETPTKTCSIADCGEL-AA 345

Query: 147 DLSVPLMDVGETAMVTADSKYCYGPQGRSPYIPPHAALCLEVTLKTAEDGPDLEMLSGQE 206
           D  V   +  ++  V AD      P   S  I   A  C E   K   D           
Sbjct: 346 DCDVTTFNKDDSGDVHADY-----PGDSS--IDFTADSCGEEVRKVVLD----------- 471

Query: 207 RVALANRKRECGNAHYQRADFVLAANSYDLAIKAITSNTKVDMTCXXXXXXXQLKVKCLN 266
                   ++ GN  ++   F  A   Y  A++ +    K+D          +   K L+
Sbjct: 472 -------VKQAGNTLFKAGKFGPANRKYKKALRYLQ---KLDEEQKMSEDQQKAMEKELH 621

Query: 267 -----NLAASQLKLDHYRAALRSCSQVLEHQPDNIKALFRKGKVLAQQGEYSEAIPILRA 321
                N AA  LKL+ Y  AL  C +VLE  PDN KA +R+G+  A   +Y  A+   + 
Sbjct: 622 IPVSLNAAACCLKLNKYNEALEYCQEVLEADPDNSKAQYRQGQAHAGNKDYETALASFQK 801

Query: 322 ALKLEPSNKTIHAELSKLVKKRAAQRSTETALYRKML 358
           AL   P +K I  E+ K+ +    ++  E  +Y +M 
Sbjct: 802 ALAANPDDKGIKLEIQKVKRTVEEEKKREKQMYSRMF 912
>26568
          Length = 398

 Score = 56.2 bits (134), Expect(2) = 1e-10,   Method: Compositional matrix adjust.
 Identities = 39/120 (32%), Positives = 61/120 (50%), Gaps = 7/120 (5%)
 Frame = +1

Query: 176 PYIPPHAALCLEVTLKTAEDGPDLEMLSGQERVALANRKRECGNAHYQRADFVLAANSYD 235
           P IP  A+L L + L   +  P +  L+ ++R+    +KRE GN  + + ++  + NSY 
Sbjct: 1   PDIPGDASLTLTLELLEVKPAPVISQLTAEDRLVFGEQKRERGNQLFSQEEYHSSINSYT 180

Query: 236 LAIK-------AITSNTKVDMTCXXXXXXXQLKVKCLNNLAASQLKLDHYRAALRSCSQV 288
           LA+K        +T NT V             K+KC NN+AA+QLK+    AA+ SC + 
Sbjct: 181 LALKYLDASFGGLTGNTSVLQNIVDS------KLKCYNNMAAAQLKIGANDAAIHSCKEF 342

 Score = 27.3 bits (59), Expect(2) = 1e-10,   Method: Compositional matrix adjust.
 Identities = 10/18 (55%), Positives = 16/18 (88%)
 Frame = +3

Query: 287 QVLEHQPDNIKALFRKGK 304
           +VL+ QP+N+KAL+R+ K
Sbjct: 336 RVLKSQPENVKALYRQAK 389
>13560
          Length = 978

 Score = 53.5 bits (127), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 38/153 (24%), Positives = 72/153 (47%), Gaps = 2/153 (1%)
 Frame = +1

Query: 202 LSGQERVALANRKRECGNAHYQRADFVLAANSYDLAIKAITSNTKVDMTCXXXXXXXQLK 261
           L+  E+ + A+  +E G  +++  +   A + +  AI+ + S      +         L+
Sbjct: 163 LTPLEKYSSASVHKEKGAQYFKTGNIFAAFSHFRTAIRLLLSVLPYSFSDDEVASTSHLQ 342

Query: 262 V--KCLNNLAASQLKLDHYRAALRSCSQVLEHQPDNIKALFRKGKVLAQQGEYSEAIPIL 319
           +  +C  NLAA Q+K  H++  + +C+  L   P N+KAL+R+       G    A   L
Sbjct: 343 LLCQCYLNLAACQIKSGHHKHVITNCTHALNLDPANVKALYRRASANVNLGNLLHAHEDL 522

Query: 320 RAALKLEPSNKTIHAELSKLVKKRAAQRSTETA 352
              L+ EP+N+ +  +L + V  R A   ++ A
Sbjct: 523 ETGLQKEPNNRAL-LDLMQNVNARLAPSQSQMA 618
>23484
          Length = 1647

 Score = 49.3 bits (116), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 38/144 (26%), Positives = 65/144 (45%), Gaps = 1/144 (0%)
 Frame = +1

Query: 208 VALANRKRECGNAHYQRADFVLAANSYDLAIKAITSNTKVDMTCXXXXXXXQLKVKCL-N 266
           VA A   RE GN  +++ D+ LA ++Y   IK+ +                +L+   L  
Sbjct: 490 VARAESYREEGNDLFKKKDYRLAVDNYXEGIKSNSPQ--------------RLQNAVLYT 627

Query: 267 NLAASQLKLDHYRAALRSCSQVLEHQPDNIKALFRKGKVLAQQGEYSEAIPILRAALKLE 326
           N AA+   L +YR+A   C    + +PD++KAL R      +  ++++ +    A L +E
Sbjct: 628 NRAAAHFHLGNYRSAFNDCFAARKFKPDHLKALVRGAMCCDKMNKHNDTLRWCDAGLMVE 807

Query: 327 PSNKTIHAELSKLVKKRAAQRSTE 350
           P +K +     K  K +  Q   E
Sbjct: 808 PGHKDLTDLKVKATKAKRIQERDE 879
>00011
          Length = 1711

 Score = 46.6 bits (109), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 25/58 (43%), Positives = 31/58 (53%)
 Frame = +1

Query: 133 LAFTLGDCDVIQALDLSVPLMDVGETAMVTADSKYCYGPQGRSPYIPPHAALCLEVTL 190
           + F +G   VI+A D  V  M VGE A +TA   Y YG  G    IPP+A L  +V L
Sbjct: 241 ICFKIGTGQVIKAWDEGVMKMSVGERATLTASPDYAYGRNGIGDIIPPNATLIFDVEL 414
>32109
          Length = 576

 Score = 42.4 bits (98), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 26/76 (34%), Positives = 41/76 (53%), Gaps = 3/76 (3%)
 Frame = +2

Query: 285 CSQVLEHQPDNIKALFRKGKVLAQQGEYSEAIPILRAALKLEPSNKTIHAELSKL---VK 341
           C + L  QP+N+KAL+ K + L    E+ +A  +   A +L+ +NK I   L +L   +K
Sbjct: 11  CHKALALQPNNVKALYHKAQALHFMSEFEQARGVYLRAQRLDSTNKAIATSLKRLDQDIK 190

Query: 342 KRAAQRSTETALYRKM 357
           K A Q    +  Y+KM
Sbjct: 191 KFAIQ----SVDYKKM 226
>01124
          Length = 1372

 Score = 38.9 bits (89), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 32/133 (24%), Positives = 56/133 (42%), Gaps = 8/133 (6%)
 Frame = -3

Query: 215 RECGNAHYQRADFVLAANSYDLAIKAITSNTKVDMTCXXXXXXXQLKVKCLNNLAASQLK 274
           R+ GN  +   ++  A N Y  A++    N K+                  +N AA  LK
Sbjct: 743 RDKGNGFFASGNYQAAVNVYTHALRL---NPKM--------------PSLYSNRAACHLK 615

Query: 275 LDHYRAALRSCSQVL--------EHQPDNIKALFRKGKVLAQQGEYSEAIPILRAALKLE 326
           L +    +  CS+ +        ++    +KA+ R+G    Q   Y E +    AALKL+
Sbjct: 614 LRNLFKCIEDCSKAMDLLSPPVPQNAASRVKAMVRRGTAFCQLEMYVEGLQDYEAALKLD 435

Query: 327 PSNKTIHAELSKL 339
           P+N+ +  +  K+
Sbjct: 434 PNNQQLKEDAEKM 396
>35348
          Length = 627

 Score = 33.9 bits (76), Expect = 0.14,   Method: Compositional matrix adjust.
 Identities = 17/65 (26%), Positives = 36/65 (55%)
 Frame = -2

Query: 265 LNNLAASQLKLDHYRAALRSCSQVLEHQPDNIKALFRKGKVLAQQGEYSEAIPILRAALK 324
           L+N AA ++K + Y+ A+  C++ ++  P  IKA FR+     +  +  +A+   R  ++
Sbjct: 458 LSNRAACRIKKEDYQKAVGDCTKSIDLNPAYIKAYFRRADAYEKLEKLDDALKDHRQVVE 279

Query: 325 LEPSN 329
           ++ S 
Sbjct: 278 MDRSQ 264
>20302
          Length = 653

 Score = 32.0 bits (71), Expect = 0.47,   Method: Compositional matrix adjust.
 Identities = 16/41 (39%), Positives = 24/41 (58%)
 Frame = +2

Query: 191 KTAEDGPDLEMLSGQERVALANRKRECGNAHYQRADFVLAA 231
           +  EDG    + +G++ V L  RK EC N H   +DF++AA
Sbjct: 470 RMKEDG---RLENGEDGVNLKGRKSECXNVHXDLSDFLVAA 583
>04645
          Length = 1075

 Score = 30.8 bits (68), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 31/127 (24%), Positives = 52/127 (40%), Gaps = 17/127 (13%)
 Frame = +3

Query: 269 AASQLKLDHYRAALRSCSQVLEHQPDNIKALFRKGKVLAQQGEYSEAIPILRAALKL--- 325
            ++ LK+   + A+  CS+ +E  PD+ +    +GK     G + E+   L  A KL   
Sbjct: 567 GSAYLKMGKPKKAIHDCSKAIELNPDSAQGYKWRGKAHKLLGHWEESYHDLTLACKLDYD 746

Query: 326 EPSNKTIH---AELSKLVK-KRAAQRSTE----------TALYRKMLGNPSRLPAKCPGK 371
           + +N  +H   A   K+++ KR  +R  E              R+      R      G+
Sbjct: 747 DDANTALHDVTANAKKIMEHKRKYERQQEERELTKRKERIRKAREEYEKQKRSRVMRRGR 926

Query: 372 GAWSIPW 378
             W IPW
Sbjct: 927 PHWWIPW 947
>08670
          Length = 1307

 Score = 30.8 bits (68), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 20/67 (29%), Positives = 32/67 (47%)
 Frame = +3

Query: 262 VKCLNNLAASQLKLDHYRAALRSCSQVLEHQPDNIKALFRKGKVLAQQGEYSEAIPILRA 321
            + L N +    +L  Y  AL+   + ++   D  K  FRKG+ LA   ++SEA      
Sbjct: 474 FRFLGNRSYCYDRLQQYEKALKDAEKAIKLSKDWPKGYFRKGRALAGLCKFSEAEESFLQ 653

Query: 322 ALKLEPS 328
            LKL+ +
Sbjct: 654 VLKLDKN 674
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|85701644|ref|NP_001028308.1| family with sequence
similarity 82, member A2 [Mus musculus]
         (470 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

01906                                                                  94   8e-20
09819                                                                  31   1.2  
19049                                                                  29   3.8  
00470                                                                  29   4.9  
>01906
          Length = 1186

 Score = 94.4 bits (233), Expect = 8e-20,   Method: Compositional matrix adjust.
 Identities = 48/135 (35%), Positives = 73/135 (54%)
 Frame = -1

Query: 336  HEGISKRIQSGFSFKEHVDKAIELQPEDPRGHFLLGRWCYQVSHLNWLEKKTATALFESP 395
            +EG   RI + +  KEH  KA EL P+D    + LG WC+  + + W ++K A ALF SP
Sbjct: 1186 YEGTKARISNAYVVKEHFMKATELNPKDATTLYTLGVWCFLFADMPWYQRKIAGALFASP 1007

Query: 396  LSATVQDALQSFLKAEELQPGFSKAGRVYISKCYRELGKNSEARKWMKLAQELPDVTNED 455
             ++T  +AL+ F KAEE +P F     + + K Y  LG    A   +  A++ P VT +D
Sbjct: 1006 PTSTYAEALEFFQKAEETEPNFFSKNTMMLGKTYLRLGDKKLAMLHLTRARDFPLVTPDD 827

Query: 456  SAFQKDLEELEVILG 470
            +   K+  +L   +G
Sbjct: 826  TEAHKEATDLLTKMG 782
>09819
          Length = 1877

 Score = 30.8 bits (68), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 17/55 (30%), Positives = 26/55 (47%)
 Frame = +2

Query: 271 YGSRQDFLWRLARAYSDMSDLTEEESGKKSYALNGKEEAEAALKKGDESAACHLW 325
           +GSR++  + L   YS M  + +EE  + S     KEE E  +  G   A   +W
Sbjct: 629 FGSREEPFFPLNEGYSFMETVDQEERVRGSLPPTAKEECEILMMVGLPGAGKTVW 793
>19049
          Length = 963

 Score = 29.3 bits (64), Expect = 3.8,   Method: Compositional matrix adjust.
 Identities = 13/32 (40%), Positives = 18/32 (56%)
 Frame = -2

Query: 28  CVLYSQRWKRTQRHGRSHSLPNSLDYAQASER 59
           C  YSQRWK +  H R  SL + L +   ++R
Sbjct: 482 CPAYSQRWKYSNDHPRHRSLNSRLSWTLRNKR 387
>00470
          Length = 1314

 Score = 28.9 bits (63), Expect = 4.9,   Method: Compositional matrix adjust.
 Identities = 15/35 (42%), Positives = 18/35 (51%)
 Frame = +3

Query: 419 KAGRVYISKCYRELGKNSEARKWMKLAQELPDVTN 453
           K G  +  KC R LGKN E R  ++L  E    TN
Sbjct: 219 KKGTQFTRKCRRSLGKNCELRSNVQLFSEXSH*TN 323
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|23956202|ref|NP_081484.1| 3-hydroxybutyrate
dehydrogenase, type 2 [Mus musculus]
         (245 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

12758                                                                  93   9e-20
03983                                                                  93   9e-20
03060                                                                  74   5e-14
28229                                                                  48   4e-13
18534                                                                  64   7e-11
05690                                                                  61   4e-10
18041                                                                  56   2e-08
20818                                                                  52   2e-07
36857                                                                  52   3e-07
30783                                                                  50   6e-07
21038                                                                  50   9e-07
36378                                                                  41   5e-04
05235                                                                  41   5e-04
31234                                                                  40   0.001
23588                                                                  38   0.004
35662                                                                  37   0.009
12661                                                                  31   0.44 
31385                                                                  27   8.1  
>12758
          Length = 804

 Score = 93.2 bits (230), Expect = 9e-20,   Method: Compositional matrix adjust.
 Identities = 64/195 (32%), Positives = 101/195 (51%), Gaps = 8/195 (4%)
 Frame = -1

Query: 56  VLDVTK----KRQIDQFASEIERIDVLFNVAGFVHHGTILDCEEKDWDFSMNLNVRSMFL 111
           V D+TK    KR +++   +  R+++L N AG +  G I +     +D   N NVRS++ 
Sbjct: 723 VGDLTKEDDTKRVVEETVKQFGRLNILVNCAGIIELGNIENTSLDQYDRMFNTNVRSVYH 544

Query: 112 MIKAFLPKMLAQKSGNIINMSSVASSIKGVENRCVYSATKAAVIGLTKSVAADFIQQGIR 171
           +    +P  L    GNI+N+SSV + ++   N   Y   K+A+   T+ VA +   + +R
Sbjct: 543 LTMLAVPH-LVNTQGNIVNVSSV-NGMRSFPNVLAYCMAKSAIDQFTRCVALELAPKKVR 370

Query: 172 CNCVCPGTVDTPSLQERIQARDNPKEALKTFLNRQKT----GRFASAEEVALLCVYLASD 227
            N V PG +    LQ+R    D   EA   FL R K     GR    EEVA    +LAS+
Sbjct: 369 VNGVNPGVI-ISELQKRGGLDD---EAYAKFLERSKETHALGRPGQPEEVARXIAFLASE 202

Query: 228 ESAYVTGNPVIIDGG 242
           +++++TG  + +DGG
Sbjct: 201 DASFITGASLPVDGG 157
>03983
          Length = 1099

 Score = 93.2 bits (230), Expect = 9e-20,   Method: Compositional matrix adjust.
 Identities = 58/190 (30%), Positives = 100/190 (52%), Gaps = 11/190 (5%)
 Frame = +2

Query: 4   LDGKVIVLTAAAQGIGRASALAFAREGAKVIATDINESKLQELESYRGIQT----RVLDV 59
           ++G+ +++T A  G+G+  A  F   G  ++  DIN   ++ +E   G Q       +D+
Sbjct: 170 VEGQRVLITGAGSGLGKLMAYRFMGLGCDLVLWDINTEAIEAMERDMGQQVSCKAYTVDL 349

Query: 60  TKKRQI----DQFASEIERIDVLFNVAGFVHHGTILDCEEKDWDFSMNLNVRSMFLMIKA 115
           + + QI    DQ   E+  +D+L N AG V     LDC +   + +M +N  + F  +KA
Sbjct: 350 SSREQIYKAADQVKREVGGVDILVNNAGIVTGRKFLDCPDSLIEKTMEVNSNAHFWTVKA 529

Query: 116 FLPKMLAQKSGNIINMSSVASSIKGVENRCVYSATKAAVIGLTKSVAADFI---QQGIRC 172
           FLP MLAQ  G+II+++S ++ + GV     Y A+K A +G  +S+  +     + G+  
Sbjct: 530 FLPNMLAQNKGHIISIAS-SAGLFGVTGLADYCASKFAAVGFDESLRFELEAMGKTGVHT 706

Query: 173 NCVCPGTVDT 182
             VCP  ++T
Sbjct: 707 TVVCPYFINT 736
>03060
          Length = 1893

 Score = 73.9 bits (180), Expect = 5e-14,   Method: Compositional matrix adjust.
 Identities = 55/193 (28%), Positives = 95/193 (49%), Gaps = 14/193 (7%)
 Frame = -1

Query: 4    LDGKVIVLTAAAQGIGRASALAFAREGAKVIATDINESKLQELESY--------RGIQTR 55
            + GKV+++T A+ G+G+A A  F + G +VI    +  +L  ++ Y        +  +  
Sbjct: 1695 IQGKVVLVTGASSGLGKACAKVFHQHGCQVILAGRSVERLNAVKDYLTKSEGEVKACEPS 1516

Query: 56   VL-----DVTKKRQIDQFASEI-ERIDVLFNVAGFVHHGTILDCEEKDWDFSMNLNVRSM 109
            VL     D+   +Q+ + A E+  ++DV+ N AG  + G I D   +     M +N    
Sbjct: 1515 VLAMDLEDLNSLQQLAERAVELFGKVDVVINNAGISYRGCIEDTSIQVDQKLMAVNYFGH 1336

Query: 110  FLMIKAFLPKMLAQKSGNIINMSSVASSIKGVENRCVYSATKAAVIGLTKSVAADFIQQG 169
              +IK  LP M A+ SG+I+ +SSV   I  +  R  YSA+K A+      + A+     
Sbjct: 1335 VALIKGLLPHMQARNSGHIVGISSVQGKIS-IPYRSAYSASKHALQAFFDCLRAELSCTK 1159

Query: 170  IRCNCVCPGTVDT 182
            I+ + + PG + T
Sbjct: 1158 IKVSLLSPGYIKT 1120
>28229
          Length = 633

 Score = 48.1 bits (113), Expect(2) = 4e-13,   Method: Compositional matrix adjust.
 Identities = 36/108 (33%), Positives = 55/108 (50%), Gaps = 9/108 (8%)
 Frame = -2

Query: 14  AAQGIGRASALAFAREGAKVIATDINESKLQE-----LESYRGIQTR--VLDVTKKRQ-- 64
           A+ GIG A A   AREGA +     N + L+       +   G+Q    V DVT      
Sbjct: 632 ASSGIGVAIAQVLAREGAVLSLVGRNVTNLEATRTTLQQQTTGVQVLNVVADVTTDSAAI 453

Query: 65  IDQFASEIERIDVLFNVAGFVHHGTILDCEEKDWDFSMNLNVRSMFLM 112
           I Q  +   RIDVL N AG + +G ++D +  ++D  +N N+R++ L+
Sbjct: 452 IQQTINHYGRIDVLVNNAGILGNGPLIDLDIAEFDAVLNTNLRAIVLL 309

 Score = 43.1 bits (100), Expect(2) = 4e-13,   Method: Compositional matrix adjust.
 Identities = 37/101 (36%), Positives = 50/101 (49%), Gaps = 4/101 (3%)
 Frame = -1

Query: 114 KAFLPKMLAQKSGNIINMSSVASSIKGVENRCVYSATKAAVIGLTKSVAADFIQQGIRCN 173
           KA LP +L  K G ++N+SS A  I        Y  +KAA+   TK V+ +   QG+R N
Sbjct: 306 KAALPHLLKTK-GAVVNVSSCAG-ICHFPGALSYGISKAALDQFTKIVSLELAPQGVRVN 133

Query: 174 CVCPGTVDTPSLQERIQARDNPKEALKTF----LNRQKTGR 210
            V PG V T ++  RI   D   EA K+     +N    GR
Sbjct: 132 SVNPGFVVT-NIHSRIGIVD---EAYKSLHERAINSHPMGR 22
>18534
          Length = 406

 Score = 63.5 bits (153), Expect = 7e-11,   Method: Compositional matrix adjust.
 Identities = 42/136 (30%), Positives = 68/136 (50%), Gaps = 14/136 (10%)
 Frame = -2

Query: 56  VLDVTKKRQIDQFASEI----ERIDVLFNVAGFVHHGTILDCEEKDWDF-------SMNL 104
           V+D++ + QI Q A+++      +DVL N AG V       C +  W+        + N+
Sbjct: 390 VVDISDREQIYQRAAQVIDDVGHVDVLINNAGIV-------CCKPFWELHDRVIQNTYNI 232

Query: 105 NVRSMFLMIKAFLPKMLAQKSGNIINMSSVASSIKGVENRCVYSATKAAVIGLTKSVAAD 164
           N+ S +  +KAFLP M+    G+I+ + SV + + G      Y+ATK A IG  +S+  D
Sbjct: 231 NIISHYWTVKAFLPHMMRHNRGHIVTVGSV-TGMLGTYGCSDYAATKYACIGFHESLLTD 55

Query: 165 FIQQG---IRCNCVCP 177
               G   I  + +CP
Sbjct: 54  LKAHGYDQIHMSLICP 7
>05690
          Length = 1192

 Score = 60.8 bits (146), Expect = 4e-10,   Method: Compositional matrix adjust.
 Identities = 56/197 (28%), Positives = 91/197 (46%), Gaps = 11/197 (5%)
 Frame = +2

Query: 5   DGKVIVLTAAAQGIGRASALAFAREGAKVIATDI-----NESKLQELESYRGIQTRVLDV 59
           +GK + +T    G+G   A+   + G KV A  +      E  L+   S R + T  LDV
Sbjct: 170 EGKAVFITGCDAGLGHLLAIHLDKLGVKVFAGCLFPGGEGEQTLKAKCSQR-LCTVPLDV 346

Query: 60  TKKRQIDQFASEIER------IDVLFNVAGFVHHGTILDCEEKDWDFSMNLNVRSMFLMI 113
                +   A  ++R      +  + N AG +H G +    + D D  +++N R    +I
Sbjct: 347 CSLEIVTTAADTVKRELDGQELWGVVNNAGIMHIGCLEVMGQADVDKILDVNYRGQVNVI 526

Query: 114 KAFLPKMLAQKSGNIINMSSVASSIKGVENRCVYSATKAAVIGLTKSVAADFIQQGIRCN 173
           +AFLP  L +  G ++N++S  + I  V    VY A+KAAV  LT+S+  +    G+R +
Sbjct: 527 RAFLP-FLRRSRGRLVNVAS-NTGIAPVPYHAVYCASKAAVAALTESLRLELQPFGVRVS 700

Query: 174 CVCPGTVDTPSLQERIQ 190
            + P    T   Q   Q
Sbjct: 701 TIIPSGYRTGIQQHNTQ 751
>18041
          Length = 547

 Score = 55.8 bits (133), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 48/183 (26%), Positives = 86/183 (46%), Gaps = 13/183 (7%)
 Frame = -2

Query: 13  AAAQGIGRASALAFAREGAKVIATDINESKL----QELESYRGIQTRVL--DVTKKRQID 66
            +  GIG+  AL  A +G  ++    N  KL    +E+     +  +V+  D       D
Sbjct: 546 GSTDGIGKCFALQLAEKGLDIVLISRNPEKLSAVAKEIVDQHKVSVKVITADFKNADIYD 367

Query: 67  QFASEIERIDV--LFNVAGFVHH-GTILDCEEKDWD-FS---MNLNVRSMFLMIKAFLPK 119
               ++  +D+  L N  G ++       CE  D++ F    +N+N+ +   M    LP+
Sbjct: 366 NIKRQLTGLDIGILVNNVGMLNRRNPGYFCEADDFEQFHQDIINVNILACVQMTGIVLPE 187

Query: 120 MLAQKSGNIINMSSVASSIKGVENRCVYSATKAAVIGLTKSVAADFIQQGIRCNCVCPGT 179
           ML +K G IIN++S  ++I+ +    VYS TKA +   T+++  ++  QG+    + P  
Sbjct: 186 MLERKRGLIINIAS-GAAIRPLPFFSVYSGTKAFISHFTQALNMEYSSQGVTIQLLIPNL 10

Query: 180 VDT 182
           V T
Sbjct: 9   VAT 1
>20818
          Length = 613

 Score = 52.0 bits (123), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 31/95 (32%), Positives = 47/95 (49%)
 Frame = +1

Query: 151 KAAVIGLTKSVAADFIQQGIRCNCVCPGTVDTPSLQERIQARDNPKEALKTFLNRQKTGR 210
           +A V  LTKS++ ++   G+R NCV PG+       E   A     +     L      R
Sbjct: 22  RAGVENLTKSLSIEWASDGVRINCVAPGS---SIYSETAAANYGSLDIFSKNLESVPLNR 192

Query: 211 FASAEEVALLCVYLASDESAYVTGNPVIIDGGWSL 245
           F + EEV+    +L S  +A++TG  + +DGG SL
Sbjct: 193 FGTTEEVSAAVCFLLSPAAAFITGETIKVDGGSSL 297
>36857
          Length = 697

 Score = 51.6 bits (122), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 39/110 (35%), Positives = 58/110 (52%), Gaps = 2/110 (1%)
 Frame = +3

Query: 122 AQKSGNIINMSSVASSIKGVENRCVYSATKAAVIGLTKSVAA--DFIQQGIRCNCVCPGT 179
            ++  +IIN+SS A  ++      VY  TKA V+  ++SVAA  D+I  GIR N +CP  
Sbjct: 249 GERGASIINISS-AGGLRPQPVGPVYCGTKAGVMMFSRSVAAHKDYIDNGIRVNTLCPAF 425

Query: 180 VDTPSLQERIQARDNPKEALKTFLNRQKTGRFASAEEVALLCVYLASDES 229
           VDTP + +      +   A K+    ++ G   S EEVA     L +D+S
Sbjct: 426 VDTPLVAKLASGLSDDTAAAKSL---EEIG-IMSVEEVAKGFYELITDDS 563
>30783
          Length = 765

 Score = 50.4 bits (119), Expect = 6e-07,   Method: Compositional matrix adjust.
 Identities = 41/120 (34%), Positives = 61/120 (50%), Gaps = 4/120 (3%)
 Frame = +1

Query: 126 GNIINMSSVASSIKGVENRCVYSATKAAVIGLTKSVAADFIQQGIRCNCVCPGTVDTPSL 185
           G I+N+SS+ +S + +    VY  +KAA+   T+ +A +    G+R N V PG+V   S+
Sbjct: 181 GCIVNVSSICAS-RPMAEVGVYCMSKAAMDMFTQCLALELAPHGVRVNSVNPGSVV--SM 351

Query: 186 QERIQARDNPKEALKTFLNRQK----TGRFASAEEVALLCVYLASDESAYVTGNPVIIDG 241
             R        E    FL  QK     G  A  E+VA    +LAS+ S +V+G  + IDG
Sbjct: 352 IYRRGPSGYNDEDYAKFLESQKGKHPLGDVAVPEDVANSIAFLASNMSRFVSGTGLFIDG 531
>21038
          Length = 377

 Score = 50.1 bits (118), Expect = 9e-07,   Method: Compositional matrix adjust.
 Identities = 32/122 (26%), Positives = 57/122 (46%), Gaps = 10/122 (8%)
 Frame = +3

Query: 24  LAFAREGAKVIATDINESKLQELESYRGIQTRVL------DVTKKRQIDQFASEIER--- 74
           L  AR G KV   D+N     E         R        DV+  R++   A  +E+   
Sbjct: 9   LELARRGCKVAVVDVNSKGCYETVELLSKIPRCTAKAYKNDVSSPRELQLMAVRVEKELG 188

Query: 75  -IDVLFNVAGFVHHGTILDCEEKDWDFSMNLNVRSMFLMIKAFLPKMLAQKSGNIINMSS 133
            +++L N A  +   +    +  + D  + LN+ S  +  K FLPKM+ +KSG+++ +++
Sbjct: 189 PVEILVNNASLMPMTSTPHLKSDEIDTILQLNLGSYIMTTKEFLPKMITRKSGHLVAVNA 368

Query: 134 VA 135
           +A
Sbjct: 369 LA 374
>36378
          Length = 552

 Score = 40.8 bits (94), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 31/108 (28%), Positives = 51/108 (47%), Gaps = 4/108 (3%)
 Frame = -3

Query: 74  RIDVLFNVAGFVHHG----TILDCEEKDWDFSMNLNVRSMFLMIKAFLPKMLAQKSGNII 129
           +ID+L N AG         T LD + +     + LNV  +  + KA LP M+ +  G+++
Sbjct: 367 QIDILVNNAGRSQRAEWVKTSLDVDRQ----MLELNVLGVLSLTKAVLPHMMQRGRGHMV 200

Query: 130 NMSSVASSIKGVENRCVYSATKAAVIGLTKSVAADFIQQGIRCNCVCP 177
            MSS+A    G      Y+ +K A+ G  +S+  +     +R  C  P
Sbjct: 199 VMSSIAGKC-GAPMSGSYTGSKHALHGWFESLRVEGHADTLR*PCCVP 59
>05235
          Length = 944

 Score = 40.8 bits (94), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 49/190 (25%), Positives = 77/190 (40%), Gaps = 12/190 (6%)
 Frame = -2

Query: 6   GKVIVLTAAAQGIGRASALAFAREGAK--VIATDI-NESKLQELE--------SYRGIQT 54
           GK I+  A   GIG  +     + G K  VI   I N + + EL+        SY     
Sbjct: 871 GKNIIFVAGLGGIGLDTNHEIVKSGPKNLVILDRIENPAAIAELKAINPKVTISYYPYDV 692

Query: 55  RVLDVTKKRQIDQFASEIERIDVLFNVAGFVHHGTILDCEEKDWDFSMNLN-VRSMFLMI 113
            V      + +    ++++++D+L N AG      ILD  + +   ++N     +    I
Sbjct: 691 TVSVAESVKLLKTVFAQLKKVDLLINGAG------ILDDHQIERTIAVNFTGTVNTTTAI 530

Query: 114 KAFLPKMLAQKSGNIINMSSVASSIKGVENRCVYSATKAAVIGLTKSVAADFIQQGIRCN 173
             F  K      G I N+ SV +    +    VYSA+KA  +  T S+A      G+   
Sbjct: 529 MEFWDKRKGGPGGVIANICSV-TGFNSIYQVPVYSASKAXALSFTNSLAKLAHITGVTVY 353

Query: 174 CVCPGTVDTP 183
            + PG   TP
Sbjct: 352 SINPGITHTP 323
>31234
          Length = 476

 Score = 39.7 bits (91), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 22/56 (39%), Positives = 33/56 (58%), Gaps = 2/56 (3%)
 Frame = +2

Query: 147 YSATKAAVIGLTK--SVAADFIQQGIRCNCVCPGTVDTPSLQERIQARDNPKEALK 200
           Y+A+K A+ GLT+  S+     + G+R  C+CP   DTP  Q + ++   PKEA K
Sbjct: 32  YTASKFAISGLTQCWSLNPHIKEMGLRFACLCPAFTDTPMXQNK-ESLLYPKEAEK 196
>23588
          Length = 611

 Score = 37.7 bits (86), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 24/69 (34%), Positives = 38/69 (55%)
 Frame = +3

Query: 65  IDQFASEIERIDVLFNVAGFVHHGTILDCEEKDWDFSMNLNVRSMFLMIKAFLPKMLAQK 124
           +D+F     +IDVL N AGF + G + B   ++     +LN+ +   M K  +P +L Q 
Sbjct: 192 VDKFG----QIDVLVNNAGFANPGLLSBPGMENLLNVFSLNLNAHVAMSKLCVPHLL-QS 356

Query: 125 SGNIINMSS 133
            GNI+N+SS
Sbjct: 357 KGNIVNISS 383
>35662
          Length = 242

 Score = 36.6 bits (83), Expect = 0.009,   Method: Composition-based stats.
 Identities = 16/47 (34%), Positives = 26/47 (55%)
 Frame = +2

Query: 199 LKTFLNRQKTGRFASAEEVALLCVYLASDESAYVTGNPVIIDGGWSL 245
            + F +R    R+ + EEV+    +L S  +A++TG  V +DGG  L
Sbjct: 23  FEVFRDRVPAKRYGTVEEVSATVCFLLSPAAAFITGETVYVDGGGKL 163
>12661
          Length = 484

 Score = 31.2 bits (69), Expect = 0.44,   Method: Compositional matrix adjust.
 Identities = 20/49 (40%), Positives = 25/49 (51%), Gaps = 4/49 (8%)
 Frame = -1

Query: 197 EALKTFLNRQK----TGRFASAEEVALLCVYLASDESAYVTGNPVIIDG 241
           E    FL  QK     G  A  E+VA    +LASD S +V+G  + IDG
Sbjct: 475 EDYAKFLESQKGKHPLGBVAVPEDVANSIAFLASDMSRFVSGTGLFIDG 329
>31385
          Length = 424

 Score = 26.9 bits (58), Expect = 8.1,   Method: Compositional matrix adjust.
 Identities = 13/24 (54%), Positives = 15/24 (62%)
 Frame = -3

Query: 160 SVAADFIQQGIRCNCVCPGTVDTP 183
           S  A F+QQG RC C  PGT+  P
Sbjct: 74  STIALFLQQG-RCPCTPPGTLAAP 6
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|40254247|ref|NP_766383.2| sterile alpha and
HEAT/Armadillo motif containing 1 [Mus musculus]
         (724 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

19986                                                                  95   9e-20
07218                                                                  36   0.050
31117                                                                  31   1.9  
>19986
          Length = 444

 Score = 95.1 bits (235), Expect = 9e-20,   Method: Compositional matrix adjust.
 Identities = 61/144 (42%), Positives = 80/144 (55%), Gaps = 2/144 (1%)
 Frame = +1

Query: 249 RAAEWLFPLAFSKEDELLRLHACLAVAVLATNKEVEREVEHSGTLALVEPLVASLDPGRF 308
           R   WLFPLAF  +D  +R +ACLA+AVL +NKE+E  V  SGTL+LV P + S DP  F
Sbjct: 31  RHQRWLFPLAFV-DDHSIRYYACLAIAVLVSNKEIETCVLKSGTLSLVLPFIDSHDPQEF 207

Query: 309 ARCLVDASDTS--QGRGPXXXXXXXXXXXXXXXEAQCIGAFYLCAEAAIKSLQGKTKVFS 366
           A     A DTS   GR                 EAQ + AF++  EA IK+ Q + +V  
Sbjct: 208 A-----AMDTSHQHGRSSGWLRRLVPVLSSKREEAQALAAFHMAMEAGIKAEQDRKEVLY 372

Query: 367 DIGAIQSLKRLVSYSTNGTTSALA 390
           ++ A+ +LK L S + N T S LA
Sbjct: 373 EVDAVDTLKWLAS-TPNSTASRLA 441
>07218
          Length = 1715

 Score = 36.2 bits (82), Expect = 0.050,   Method: Compositional matrix adjust.
 Identities = 21/65 (32%), Positives = 32/65 (49%)
 Frame = +1

Query: 409 VASWKEAEVQTWLQQIGFSQYCENFREQQVDGDLLLRLTDEELQTDLGMKSSITRKRFFR 468
           + SW   EV  WL+ +   +Y  NF   ++ G  LL L   +L+ DLG+      KR  +
Sbjct: 190 IRSWTTDEVGAWLESLSLGEYRANFISHEIRGAELLSLERRDLK-DLGVTKVGHLKRIQQ 366

Query: 469 ELTEL 473
            + EL
Sbjct: 367 AIKEL 381
>31117
          Length = 856

 Score = 30.8 bits (68), Expect = 1.9,   Method: Compositional matrix adjust.
 Identities = 11/39 (28%), Positives = 19/39 (48%)
 Frame = +3

Query: 406 LPCVASWKEAEVQTWLQQIGFSQYCENFREQQVDGDLLL 444
           +P    W   +V  W++++GF  Y   F    +DG  L+
Sbjct: 72  IPNAMYWTVNQVAEWIEELGFPHYKSCFTTNMIDGRRLI 188
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|158518433|ref|NP_075550.2| LIM domain and actin
binding 1 isoform b [Mus musculus]
         (593 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

04349                                                                  94   1e-19
30169                                                                  49   5e-06
03731                                                                  49   8e-06
05825                                                                  44   1e-04
05103                                                                  35   0.085
11928                                                                  33   0.24 
23209                                                                  33   0.26 
24984                                                                  31   0.27 
14307                                                                  33   0.31 
20032                                                                  28   8.4  
>04349
          Length = 1161

 Score = 94.4 bits (233), Expect = 1e-19,   Method: Compositional matrix adjust.
 Identities = 40/86 (46%), Positives = 53/86 (61%)
 Frame = +3

Query: 226 ESCVECQKTVYPMERLLANQQVFHISCFRCSYCNNKLSLGTYASLHGRIYCKPHFNQLFK 285
           E C  C KTVY ME++   +  +H SCFRCS+C+  L+  T+A     ++C  H+ QLF 
Sbjct: 225 EKCGACHKTVYAMEKIEIEKNAYHKSCFRCSHCHCVLTPKTFAINKNVMFCTNHYKQLFA 404

Query: 286 SKGNYDEGFGHKQHKDLWASKSDNEE 311
           +KGNYDEGFGH QHK  W      +E
Sbjct: 405 TKGNYDEGFGHSQHKKRWTMDVSGQE 482
>30169
          Length = 426

 Score = 48.9 bits (115), Expect = 5e-06,   Method: Composition-based stats.
 Identities = 24/72 (33%), Positives = 32/72 (44%), Gaps = 1/72 (1%)
 Frame = -1

Query: 226 ESCVECQKTVYPMERLLANQQVFHISCFRCSYCNNKLSLGTYASLHGRIYCKPHFNQLFK 285
           E C  C K VY  ER+    +V+H +CF+C+ C   L           IYCK  + + F 
Sbjct: 411 EMCAVCGKAVYFAERVAGMGKVYHKACFKCTSCRKILDSTLLTQHQDNIYCKACYGKNFG 232

Query: 286 SKG-NYDEGFGH 296
            KG  Y     H
Sbjct: 231 PKGFGYGSALAH 196
>03731
          Length = 728

 Score = 48.5 bits (114), Expect = 8e-06,   Method: Compositional matrix adjust.
 Identities = 20/43 (46%), Positives = 28/43 (65%)
 Frame = +2

Query: 226 ESCVECQKTVYPMERLLANQQVFHISCFRCSYCNNKLSLGTYA 268
           E C  C KTVY ME++   +  +H SCFRCS+C+  L+  T+A
Sbjct: 581 EKCGACHKTVYAMEKIEIEKNAYHKSCFRCSHCHCVLTPKTFA 709
>05825
          Length = 1225

 Score = 44.3 bits (103), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 18/30 (60%), Positives = 23/30 (76%)
 Frame = -2

Query: 279  HFNQLFKSKGNYDEGFGHKQHKDLWASKSD 308
            H+ QLF +KGNYDEGFG  QHK  W S+++
Sbjct: 1137 HYKQLFATKGNYDEGFGRDQHKKRWKSETN 1048

 Score = 29.3 bits (64), Expect = 5.3,   Method: Compositional matrix adjust.
 Identities = 15/44 (34%), Positives = 22/44 (50%)
 Frame = -1

Query: 251  SCFRCSYCNNKLSLGTYASLHGRIYCKPHFNQLFKSKGNYDEGF 294
            SCFRCS+C+  L+  T+A     +YC      +   +G    GF
Sbjct: 1222 SCFRCSHCHCILTPKTFAINKNVMYCTKPLQAVICHQGQLRRGF 1091
>05103
          Length = 1504

 Score = 35.0 bits (79), Expect = 0.085,   Method: Compositional matrix adjust.
 Identities = 12/40 (30%), Positives = 22/40 (55%)
 Frame = +2

Query: 243 ANQQVFHISCFRCSYCNNKLSLGTYASLHGRIYCKPHFNQ 282
           AN   +H++CF+C  C+  L    +  +  ++YC+ H  Q
Sbjct: 686 ANGVPYHVACFKCESCSMNLKQKGFFVVDDKLYCETHARQ 805
>11928
          Length = 1623

 Score = 33.5 bits (75), Expect = 0.24,   Method: Compositional matrix adjust.
 Identities = 20/70 (28%), Positives = 34/70 (48%)
 Frame = -3

Query: 215  KTAKKFQAPAKESCVECQKTVYPMERLLANQQVFHISCFRCSYCNNKLSLGTYASLHGRI 274
            +TA+    P +  CV+  +       L    + F  S F C++C  +L+ GT+   + + 
Sbjct: 1108 RTARLTITPRRALCVQVARNQSRGAALRPCSRSFTRSIFVCAFCIKQLNKGTFKEQNDKP 929

Query: 275  YCKPHFNQLF 284
            YC P F +LF
Sbjct: 928  YCHPCFVKLF 899
>23209
          Length = 1559

 Score = 33.5 bits (75), Expect = 0.26,   Method: Compositional matrix adjust.
 Identities = 25/66 (37%), Positives = 34/66 (51%), Gaps = 4/66 (6%)
 Frame = +3

Query: 219 KFQAPAK----ESCVECQKTVYPMERLLANQQVFHISCFRCSYCNNKLSLGTYASLHGRI 274
           +++ P K    E C  C KTVY  ER+ A    FH  CF+C  C   L++  Y    G +
Sbjct: 177 RYKMPPKFGGGEKCGICSKTVYQQERVEAGGIPFHKLCFKCKCCKMSLTMNNYGQAEGVL 356

Query: 275 YCKPHF 280
           YCK H+
Sbjct: 357 YCKKHY 374
>24984
          Length = 1528

 Score = 31.2 bits (69), Expect(2) = 0.27,   Method: Compositional matrix adjust.
 Identities = 11/28 (39%), Positives = 15/28 (53%)
 Frame = +1

Query: 252 CFRCSYCNNKLSLGTYASLHGRIYCKPH 279
           CF+C  C   L++  Y    G +YCK H
Sbjct: 199 CFKCKNCKTSLAMNGYGQEEGALYCKKH 282

 Score = 20.4 bits (41), Expect(2) = 0.27,   Method: Compositional matrix adjust.
 Identities = 12/26 (46%), Positives = 13/26 (50%)
 Frame = +3

Query: 224 AKESCVECQKTVYPMERLLANQQVFH 249
           A E C    KTVY  ER+ A    FH
Sbjct: 114 AAEKCGIXTKTVYQQERVDAGGIPFH 191
>14307
          Length = 816

 Score = 33.1 bits (74), Expect = 0.31,   Method: Compositional matrix adjust.
 Identities = 24/100 (24%), Positives = 41/100 (41%), Gaps = 15/100 (15%)
 Frame = +2

Query: 221 QAPAKESCVECQKTVYPMERLL-----ANQQVFHISCFRCSYCNNKLSLGTYASLHGRIY 275
           +AP+  +C  C+  +  +E ++         V+H +CF CS C   L    Y      +Y
Sbjct: 158 EAPSDTTCHCCKGEIDKLELVVTAPKVGEGTVWHPACFVCSTCEELLVDLVYCQHDKHLY 337

Query: 276 CKPHFNQLFKSK----------GNYDEGFGHKQHKDLWAS 305
           C+ H+ +L + +          G Y +      HKD  A 
Sbjct: 338 CQRHYAELIRPRCPGCDELIFSGEYTKAMEECYHKDHLAC 457

 Score = 29.3 bits (64), Expect = 5.3,   Method: Compositional matrix adjust.
 Identities = 17/71 (23%), Positives = 37/71 (52%), Gaps = 1/71 (1%)
 Frame = +2

Query: 220 FQAPAKESCVECQKTVYPMERLLANQ-QVFHISCFRCSYCNNKLSLGTYASLHGRIYCKP 278
           +QA     C +C K + P  + L+ + + +H  CF+C+ C+  L    +A  + +I+C  
Sbjct: 530 YQALFANKCEDCDKPIGPDYKDLSYKDKHWHEFCFKCTMCDKSLVDQPFAPKNEKIFCSE 709

Query: 279 HFNQLFKSKGN 289
            ++  F ++ +
Sbjct: 710 CYDNSFAARCD 742
>20032
          Length = 363

 Score = 28.5 bits (62), Expect = 8.4,   Method: Composition-based stats.
 Identities = 19/60 (31%), Positives = 30/60 (50%)
 Frame = +2

Query: 221 QAPAKESCVECQKTVYPMERLLANQQVFHISCFRCSYCNNKLSLGTYASLHGRIYCKPHF 280
           Q+ AK+S +  QK V+ + +     Q+F    F CSY    LS GT      ++ CK ++
Sbjct: 122 QSVAKQSTLFHQK*VWLILQ*W*RSQMFGSDFFICSYLGRSLSEGTSVGPKLKLLCKYNY 301
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|160707901|ref|NP_038708.3| synapsin I isoform a [Mus
musculus]
         (706 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

11472                                                                  62   1e-19
>11472
          Length = 1283

 Score = 62.0 bits (149), Expect(2) = 1e-19,   Method: Compositional matrix adjust.
 Identities = 29/52 (55%), Positives = 39/52 (75%), Gaps = 2/52 (3%)
 Frame = -2

Query: 173  KVVRSLKPDFVLIRQHAFSMARNG--DYRSLVIGLQYAGIPSVNSLHSVYNF 222
            +V RS +PDFVLIRQ      R+G  D+RS ++GL+Y G+PS+NSLHS+Y F
Sbjct: 1222 QVARSFRPDFVLIRQPP----RDGSSDFRSTILGLKYGGVPSINSLHSIYQF 1079

 Score = 53.1 bits (126), Expect(2) = 1e-19,   Method: Compositional matrix adjust.
 Identities = 19/37 (51%), Positives = 32/37 (86%)
 Frame = -1

Query: 224  DKPWVFAQMVRLHKKLGTEEFPLIDQTFYPNHKEMLS 260
            DKPWVF+ +++L ++LG + FPLI+QTF+PN ++++S
Sbjct: 1007 DKPWVFSHLLQLQRRLGRDGFPLIEQTFFPNPRDLVS 897
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|84781781|ref|NP_001028485.1| PDGFA associated protein
1 [Mus musculus]
         (181 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

12360                                                                  92   1e-19
>12360
          Length = 1201

 Score = 92.0 bits (227), Expect = 1e-19,   Method: Compositional matrix adjust.
 Identities = 48/76 (63%), Positives = 61/76 (80%), Gaps = 2/76 (2%)
 Frame = +1

Query: 73  KRKGVEGLIDIENPNRVA-QTTKKVTQL-DLDGPKELSRREREEIEKQKAKERYMKMHLA 130
           K KGVE LI +ENPNR A +  KKV+++ D   P  LSRREREE+EKQ+A+ RY +MHLA
Sbjct: 268 KAKGVEHLISVENPNRAAGKRNKKVSEIGDAPAPTNLSRREREELEKQEARRRYQQMHLA 447

Query: 131 GKTEQAKADLARLAII 146
           GKTE+A++D+ARLAII
Sbjct: 448 GKTEEAQSDMARLAII 495
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|118601013|ref|NP_033828.2| adenine phosphoribosyl
transferase [Mus musculus]
         (180 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

19988                                                                  92   2e-19
>19988
          Length = 418

 Score = 91.7 bits (226), Expect = 2e-19,   Method: Compositional matrix adjust.
 Identities = 44/78 (56%), Positives = 58/78 (74%)
 Frame = -2

Query: 17  PDFPIPGVLFRDISPLLKDPDSFRASIRLLASHLKSTHSGKIDYIAGLDSRGFLFGPSLA 76
           PDFP PG+ FRDI P+L+DP +FR  I +L  H++   + K++ I GL+SRGFLFGP +A
Sbjct: 231 PDFPKPGINFRDIFPVLRDPKAFRNLIDILCKHVQK-FAPKVEVIVGLESRGFLFGPMMA 55

Query: 77  QELGVGCVLIRKQGKLPG 94
           ++LGV  V IRK GKLPG
Sbjct: 54  EQLGVSFVPIRKAGKLPG 1
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|124430578|ref|NP_076357.2| ryanodine receptor 2,
cardiac [Mus musculus]
         (4966 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

18861                                                                  97   2e-19
09819                                                                  40   0.016
14594                                                                  37   0.16 
01491                                                                  35   0.53 
21365                                                                  35   0.89 
05237                                                                  35   0.90 
12533                                                                  32   7.6  
03733                                                                  32   8.7  
>18861
          Length = 443

 Score = 97.1 bits (240), Expect = 2e-19,   Method: Compositional matrix adjust.
 Identities = 52/139 (37%), Positives = 72/139 (51%), Gaps = 1/139 (0%)
 Frame = -2

Query: 4805 CDDMLTCYMFHMYVGVRAGGGIGDEIEDPAGDEYEIY-RXXXXXXXXXXXXXXXXXXXQG 4863
            CD ++ C +  +  G+R GGGIGD +  P+  E   + R                    G
Sbjct: 421  CDSLIMCIVTTLNQGLRNGGGIGDVLRKPSSREPLFFARVIYDLLFFFIVIIIVLNLIFG 242

Query: 4864 LIIDAFGELRDQQEQVKEDMETKCFICGIGNDYFDTVPHGFETHTLQEHNLANYLFFLMY 4923
            +IID F +LR +++Q  E +   CFICG+  D FD     FE H   EHN+ +YLFF++ 
Sbjct: 241  VIIDTFADLRSEKQQKDEILRNSCFICGLERDKFDNRSVSFEEHIKSEHNMWHYLFFIVL 62

Query: 4924 LINKDETEHTGQESYVWKM 4942
            +  KD TE TG ESYV  M
Sbjct: 61   VNVKDSTEFTGPESYVHSM 5
>09819
          Length = 1877

 Score = 40.4 bits (93), Expect = 0.016,   Method: Compositional matrix adjust.
 Identities = 37/129 (28%), Positives = 53/129 (41%), Gaps = 15/129 (11%)
 Frame = +2

Query: 1069 QDHASRAEVCSGTGERFRIFRAEKTYAVKAGRWYFEFEAVT-------AGD------MRV 1115
            QD   +A   +  G  F    A   Y VKAG+  FE +            D      +RV
Sbjct: 158  QDGGLKANPLTVEGFAFMWSGARAMYGVKAGKVAFEVKLTENLSVDHLPSDESHPHVLRV 337

Query: 1116 GWSRPGCQPDLELGSDDRAFAFDGFKAQRWHQGNEHYGRSWQAGDVVGCMVDMNEH--TM 1173
            GWS       ++LG +  ++ + G          + YG S+ AGDV+   +DM+    TM
Sbjct: 338  GWSAD--DTSMQLGEEALSYGYGGTGKASTECQFKDYGESFTAGDVITAYLDMDSDPVTM 511

Query: 1174 MFTLNGEIL 1182
             F  NG  L
Sbjct: 512  SFAKNGTDL 538
>14594
          Length = 1014

 Score = 37.4 bits (85), Expect = 0.16,   Method: Composition-based stats.
 Identities = 19/65 (29%), Positives = 35/65 (53%), Gaps = 1/65 (1%)
 Frame = +3

Query: 4029 DTFKEYDPDGKGVISKRDFHKAMES-HKHYTQSETEFLLSCAETDENETLDYEEFVKRFH 4087
            + F  +D DG G I+  +    M S  ++ T++E + +++  + D N T+D+EEF+    
Sbjct: 453  EAFSLFDKDGDGTITTSELGTVMRSLGQNPTENELQDMINEVDADGNGTIDFEEFLHMMA 632

Query: 4088 EPAKD 4092
               KD
Sbjct: 633  RKMKD 647

 Score = 33.5 bits (75), Expect = 2.2,   Method: Composition-based stats.
 Identities = 21/71 (29%), Positives = 35/71 (49%), Gaps = 5/71 (7%)
 Frame = +3

Query: 4018 MFLKLKDLTSSDTFKE----YDPDGKGVISKRDFHKAMES-HKHYTQSETEFLLSCAETD 4072
            M  K+KD    +  +E    +D DG G IS  +    M +  +  T  E + ++  A+ D
Sbjct: 627  MARKMKDTDCEEELREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIKEADLD 806

Query: 4073 ENETLDYEEFV 4083
             +  ++YEEFV
Sbjct: 807  GDGMVNYEEFV 839
>01491
          Length = 1707

 Score = 35.4 bits (80), Expect = 0.53,   Method: Composition-based stats.
 Identities = 29/94 (30%), Positives = 44/94 (46%), Gaps = 1/94 (1%)
 Frame = +1

Query: 4031 FKEYDPDGKGVISKRDFHKAMES-HKHYTQSETEFLLSCAETDENETLDYEEFVKRFHEP 4089
            F+  D   KGVI   D    ++S     T+ E E ++   +TD + T+DYEEF    +  
Sbjct: 364  FRVLDKGNKGVIPVEDLRWLLKSLGDDLTEDEIEDMIVETDTDGSGTVDYEEFRTLMNSA 543

Query: 4090 AKDIGFNVAVLLTNLSEHMPNDTRLQTFLELAES 4123
             +        L T +S H+P+D  + T   LA S
Sbjct: 544  *RH-------LPTRVSHHIPDDV-IITVARLASS 621
>21365
          Length = 486

 Score = 34.7 bits (78), Expect = 0.89,   Method: Composition-based stats.
 Identities = 20/71 (28%), Positives = 36/71 (50%), Gaps = 4/71 (5%)
 Frame = -3

Query: 1112 DMRVGWSRPGCQPDLELGSDDRAFAFDGFKAQRWH-QGNEHYGRS---WQAGDVVGCMVD 1167
            D  +G  R        LG DD+A++      + W    +EH  R+    + G V+G ++D
Sbjct: 277  DPSIGICRFDVDKTTMLGKDDKAWSMYIDDKRSWFIHRDEHTNRTDGGIKRGTVIGLLLD 98

Query: 1168 MNEHTMMFTLN 1178
            +N+HT+ + +N
Sbjct: 97   LNQHTLSYFIN 65
>05237
          Length = 472

 Score = 34.7 bits (78), Expect = 0.90,   Method: Composition-based stats.
 Identities = 18/57 (31%), Positives = 31/57 (54%), Gaps = 1/57 (1%)
 Frame = +3

Query: 4029 DTFKEYDPDGKGVISKRDFHKAMES-HKHYTQSETEFLLSCAETDENETLDYEEFVK 4084
            + F+ +D DG G IS  +    M +  +  T  E + ++  A+ D +  ++YEEFVK
Sbjct: 39   EAFRVFDKDGNGFISASELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVK 209
>12533
          Length = 1094

 Score = 31.6 bits (70), Expect = 7.6,   Method: Composition-based stats.
 Identities = 22/68 (32%), Positives = 32/68 (47%), Gaps = 5/68 (7%)
 Frame = -1

Query: 2518 YLCTAVLP-LLTRC----APLFAGTEHHASLIDSLLHTVYRLSKGCSLTKAQRDSIEVCL 2572
            YLC  V P L+  C      L+     +  ++DS+   VYRL  GC L  A +DS    L
Sbjct: 692  YLCMNVCP*LVNECLCLHVILYDNERXYQLVLDSIGFCVYRLCLGCKLD*AXKDSRSXYL 513

Query: 2573 LSICGQLR 2580
            +    ++R
Sbjct: 512  MMTLVRVR 489
>03733
          Length = 1281

 Score = 31.6 bits (70), Expect = 8.7,   Method: Compositional matrix adjust.
 Identities = 28/129 (21%), Positives = 54/129 (41%), Gaps = 15/129 (11%)
 Frame = +1

Query: 1069 QDHASRAEVCSGTGERFRIFRAEKTYAVKAGRWYFEFEAVTAGD-------------MRV 1115
            Q+   +A   +  G  F    A   + VK+G++ +E + +   +             +RV
Sbjct: 328  QESGLKAHPLTVEGFAFMWAGARAMFGVKSGKFAYEVKLLEHLNVDHLPSDESNPHVLRV 507

Query: 1116 GWSRPGCQPDLELGSDDRAFAFDGFKAQRWHQGNEHYGRSWQAGDVVGCMVDMNEHTMM- 1174
            GWS       ++LG +  ++ + G          + YG  + +GDV+   +DM+   ++ 
Sbjct: 508  GWSVD--DTSMQLGEEALSYGYGGTGKASTECKFKDYGEKFTSGDVITAYLDMDSDPVVL 681

Query: 1175 -FTLNGEIL 1182
             F  NG  L
Sbjct: 682  SFAKNGTDL 708
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|149262515|ref|XP_181343.6| PREDICTED: similar to
likely ortholog of H. sapiens phosphoribosyl pyrophosphate
synthetase-associated protein 1 (PRPSAP1) [Mus musculus]
         (546 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

21831                                                                  93   2e-19
>21831
          Length = 1374

 Score = 93.2 bits (230), Expect = 2e-19,   Method: Compositional matrix adjust.
 Identities = 42/53 (79%), Positives = 50/53 (94%)
 Frame = -1

Query: 494 EVVVTNTVPHELQKLQCPKIKTVDISLILSEAIRRIHNGESMAYLFRNITVDD 546
           +VVVTNTVPHE++K+QC KIKTVDIS +L+EAIRRIH+GESM+YLFRNI VDD
Sbjct: 807 QVVVTNTVPHEVKKMQCHKIKTVDISSLLAEAIRRIHHGESMSYLFRNIGVDD 649
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|15617197|ref|NP_077135.1| vacuolar H+ ATPase G1 [Mus
musculus]
         (118 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

27393                                                                  91   2e-19
28262                                                                  48   1e-14
24837                                                                  25   5.8  
03948                                                                  25   8.6  
>27393
          Length = 556

 Score = 90.5 bits (223), Expect = 2e-19,   Method: Compositional matrix adjust.
 Identities = 48/115 (41%), Positives = 67/115 (58%)
 Frame = +2

Query: 2   ASQSQGIQQLLQAEKRAAEKVSEARKRKNRRLXXXXXXXXXXXXXYRLQRXXXXXXXXXX 61
           ASQ+QGIQQLL AEK+AAEKV+EAR++K  RL             Y+ +R          
Sbjct: 2   ASQTQGIQQLLAAEKKAAEKVAEARRKKANRLKAAKKEADTDINNYKAERERQYKDYEAR 181

Query: 62  XLGSHGSCSSEVEKETREKMTVLQNYFEQNRDEVLDNLLAFVCDIRPEIHENYRI 116
            LGS G   +++E  TR K+  L    ++N++E L  LL  V +I+PE+HEN R+
Sbjct: 182 ILGSKGDMEAKIEASTRLKIKELNANVDKNKEEALSKLLNIVLEIKPELHENLRL 346
>28262
          Length = 1418

 Score = 48.1 bits (113), Expect(2) = 1e-14,   Method: Compositional matrix adjust.
 Identities = 25/70 (35%), Positives = 36/70 (51%)
 Frame = +2

Query: 47  YRLQRXXXXXXXXXXXLGSHGSCSSEVEKETREKMTVLQNYFEQNRDEVLDNLLAFVCDI 106
           Y+ QR           LGS G   S++E  TR+K+  L      +++E L  LL  V +I
Sbjct: 494 YKTQRESQYQSYEAQILGSRGDMESKIESSTRQKIKELNMNVSSHKEEALRKLLDIVLNI 673

Query: 107 RPEIHENYRI 116
            PE+HEN R+
Sbjct: 674 TPELHENLRL 703

 Score = 46.2 bits (108), Expect(2) = 1e-14,   Method: Compositional matrix adjust.
 Identities = 22/28 (78%), Positives = 26/28 (92%)
 Frame = +3

Query: 1   MASQSQGIQQLLQAEKRAAEKVSEARKR 28
           MASQ+QGIQQLL AEK+AAEKV +AR+R
Sbjct: 357 MASQTQGIQQLLAAEKKAAEKVGDARRR 440
>24837
          Length = 919

 Score = 25.4 bits (54), Expect = 5.8,   Method: Compositional matrix adjust.
 Identities = 11/31 (35%), Positives = 17/31 (54%)
 Frame = +1

Query: 63  LGSHGSCSSEVEKETREKMTVLQNYFEQNRD 93
           LG+HG C + +     EK   + N+  +NRD
Sbjct: 334 LGAHGRCRNSLNSTKLEK---IWNFLTKNRD 417
>03948
          Length = 2007

 Score = 25.0 bits (53), Expect = 8.6,   Method: Composition-based stats.
 Identities = 11/14 (78%), Positives = 12/14 (85%)
 Frame = +3

Query: 92   RDEVLDNLLAFVCD 105
            RDEV D+LL FVCD
Sbjct: 1257 RDEV*DSLLLFVCD 1298
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|166295210|ref|NP_001001602.2| disabled homolog 2
interacting protein isoform 3 [Mus musculus]
         (1124 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

27553                                                                  94   2e-19
11228                                                                  59   1e-08
28193                                                                  51   3e-06
28867                                                                  38   0.025
15210                                                                  30   4.6  
05916                                                                  30   6.1  
>27553
          Length = 506

 Score = 94.4 bits (233), Expect = 2e-19,   Method: Compositional matrix adjust.
 Identities = 42/79 (53%), Positives = 60/79 (75%)
 Frame = +3

Query: 329 TDLMMSEVDRCGDNEHLIFRENTLATKAIEEYLKLVGQKYLQDALGEFIKALYESDENCE 388
           TD++M+E+DR  DNEHL FR N++ATKA+E Y+KLVG++YL D LG+F++ L  +D++CE
Sbjct: 24  TDIVMAEIDRL-DNEHLTFRGNSIATKAMEAYMKLVGERYLHDTLGDFVQNLVRADDDCE 200

Query: 389 VDPSKCSSADLPEHQGNLK 407
           VDP+K S+   P H    K
Sbjct: 201 VDPTKVST---PTHSSASK 248

 Score = 69.7 bits (169), Expect(2) = 1e-18,   Method: Compositional matrix adjust.
 Identities = 32/40 (80%), Positives = 37/40 (92%)
 Frame = +1

Query: 450 RLISASLFLRFLCPAIMSPSLFNLLQEYPDDRTARTLTLI 489
           +LISAS+FLRFLCPAI+SPSLFNL QEYP++R AR LTLI
Sbjct: 385 QLISASIFLRFLCPAILSPSLFNLTQEYPEERAARNLTLI 504

 Score = 42.4 bits (98), Expect(2) = 1e-18,   Method: Composition-based stats.
 Identities = 25/62 (40%), Positives = 32/62 (51%), Gaps = 7/62 (11%)
 Frame = +2

Query: 395 SSADLPEH-------QGNLKMCCELAFCKIINSYCVFPRELKEVFASWRQECSSRGRPDI 447
           S  D  EH       Q NL M   +A+ KIINSYC FP EL+EV   +    S +G   +
Sbjct: 200 SGPDQSEHPHTLKCQQDNLVMYANMAWVKIINSYCYFPNELREVLHLFPGPLSGQGEGGV 379

Query: 448 SE 449
           S+
Sbjct: 380 SD 385
>11228
          Length = 2155

 Score = 58.9 bits (141), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 41/171 (23%), Positives = 79/171 (46%)
 Frame = -3

Query: 219 KKERNSYLGLVSLPAASVAGRQFVEKWYPVVTXXXXXXXXXXXMIRIKARYQTVSILPME 278
           K+ R+ ++G V++  AS+  ++ V++ YP+V             +R +A Y+   +LP  
Sbjct: 512 KRNRDMFIGSVTVQLASLENQENVDEHYPMVAVGGALSKGEVGSLRFRAHYKHQVLLPQA 333

Query: 279 MYKEFAEHITNHYLGLCAALEPILSAKTKEEMASALVHILQSTGKVKDFLTDLMMSEVDR 338
            Y    E +          L  +   +    +A AL+ I  S  K    L  L   E+D+
Sbjct: 332 EYTSLKELLIEEGYENLLTLAQLCPKQEWSTLARALLRIFSSDRKEVVLLRTLNDHEIDK 153

Query: 339 CGDNEHLIFRENTLATKAIEEYLKLVGQKYLQDALGEFIKALYESDENCEV 389
             +   L FR  TLAT  +++Y+K+    +++ A+   ++ + E   +CE+
Sbjct: 152 EVEVSTL-FRATTLATTLMDQYMKMTSSDFVRQAVLRGVQKVMEMKHSCEL 3

 Score = 36.2 bits (82), Expect = 0.082,   Method: Compositional matrix adjust.
 Identities = 42/150 (28%), Positives = 60/150 (40%), Gaps = 26/150 (17%)
 Frame = -2

Query: 92  IKPVHSSILGQDYCFEV--TTSSGSKCFSCRSAAERDKWMENLRRAVHPNK--------- 140
           I P+H S  G+  CF +  T  + SK   C   AE     E +RR VH  K         
Sbjct: 912 IYPMHDSWFGRPNCFLLMSTYDNHSKTL-CYINAES---TEVIRRWVHILKASCVNTSTA 745

Query: 141 --DNSRRVEHILKLWVIEAKDLPAK--KKYLCELCLDDVLYARTTSKLKTDNVFWGEHFE 196
                 R  H L + +  A  +P K      C   L+    ART +  ++ + FWGE F 
Sbjct: 744 PPGKGLRSLHSLSVTIFSAHHVPVKLLSHPACIFSLNQHRVARTQT-CESGDPFWGEEFT 568

Query: 197 FHNLPP-----------LRTVTVHLYRETD 215
             ++PP            +T   H+YR +D
Sbjct: 567 LDDIPPRCGEFHSVSHQXQTQQGHVYRVSD 478
>28193
          Length = 457

 Score = 50.8 bits (120), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 22/48 (45%), Positives = 33/48 (68%)
 Frame = -3

Query: 346 IFRENTLATKAIEEYLKLVGQKYLQDALGEFIKALYESDENCEVDPSK 393
           +FR N+L +K I+E +KLVG  YL D L  FI ++ +  + CE+DPS+
Sbjct: 239 LFRGNSLLSKMIDELMKLVGLPYLHDTLKVFIDSVCDEPKPCEIDPSR 96
>28867
          Length = 345

 Score = 37.7 bits (86), Expect = 0.025,   Method: Composition-based stats.
 Identities = 19/60 (31%), Positives = 34/60 (56%)
 Frame = -3

Query: 56  RSHLMPRLKXXXXXXXXXXXXXAVEALDLSMEEEVIIKPVHSSILGQDYCFEVTTSSGSK 115
           RS +  RL+             A++A+D++   +V +K VH +++ +D+CF +TT  GSK
Sbjct: 181 RSLISSRLRAARSHESLLSNPSAMQAVDVT-GRDVQVKAVHHTLVSRDHCFHITTPQGSK 5
>15210
          Length = 729

 Score = 30.4 bits (67), Expect = 4.6,   Method: Compositional matrix adjust.
 Identities = 14/42 (33%), Positives = 21/42 (50%)
 Frame = +3

Query: 332 MMSEVDRCGDNEHLIFRENTLATKAIEEYLKLVGQKYLQDAL 373
           + S +DR  DN  ++  EN L  + I EYL+    +Y    L
Sbjct: 6   VYSAIDRPADNRPVVSNENILINELIREYLEFNKYQYTSSVL 131
>05916
          Length = 1120

 Score = 30.0 bits (66), Expect = 6.1,   Method: Composition-based stats.
 Identities = 18/47 (38%), Positives = 28/47 (59%)
 Frame = +1

Query: 328 LTDLMMSEVDRCGDNEHLIFRENTLATKAIEEYLKLVGQKYLQDALG 374
           L  ++ S+VD C  N+ L+    +++T    E +KLV QK + DALG
Sbjct: 217 LAFVVHSQVDVCAGNQSLMHLLPSIST----ETVKLVKQKSIADALG 345
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31542873|ref|NP_080969.2| gamma-aminobutyric acid
(GABA-A) receptor-associated protein-like 2 [Mus musculus]
         (117 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

26955                                                                  90   2e-19
26956                                                                  87   2e-18
>26955
          Length = 863

 Score = 90.1 bits (222), Expect = 2e-19,   Method: Compositional matrix adjust.
 Identities = 42/102 (41%), Positives = 70/102 (68%), Gaps = 2/102 (1%)
 Frame = -1

Query: 17  ESAKIRAKYPDRVPVIVEKVSGSQIV-DIDKRKYLVPSDITVAQFMWIIRKRIQLPSEKA 75
           E   IR K+P ++PVIVE+    +++  +DK K+LVP ++T++QF+ IIR R+ L S ++
Sbjct: 320 EVEGIRNKFPTKIPVIVERYHKEKVLATLDKTKFLVPQELTMSQFLTIIRNRMSLTSNQS 141

Query: 76  IFLFV-DKTVPQSSLTMGQLYEKEKDEDGFLYVAYSGENTFG 116
           I+L V +K++   S T+ ++Y  +KD DGFLY+ Y+ +  FG
Sbjct: 140 IYLLVNNKSLSSMSSTIAEVYRDDKDPDGFLYMTYASQEMFG 15
>26956
          Length = 450

 Score = 86.7 bits (213), Expect = 2e-18,   Method: Compositional matrix adjust.
 Identities = 44/106 (41%), Positives = 71/106 (66%), Gaps = 2/106 (1%)
 Frame = -2

Query: 5   FKEDHSLEHRCVESAKIRAKYPDRVPVIVEKVSGSQIV-DIDKRKYLVPSDITVAQFMWI 63
           FK+  SL  R  E   IR K+P ++PVIVE+    +++  +DK K+LVP ++T++QF+ I
Sbjct: 320 FKQRKSLAVRKEEVEGIRNKFPTKIPVIVERYHKEKVLATLDKTKFLVPQELTMSQFLTI 141

Query: 64  IRKRIQLPSEKAIFLFV-DKTVPQSSLTMGQLYEKEKDEDGFLYVA 108
           IR R+ L S ++I+L V +K++   S T+ ++Y  +KD DGFLY+ 
Sbjct: 140 IRNRMSLTSNQSIYLLVNNKSLSSMSSTIAEVYRDDKDPDGFLYMT 3
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|149254556|ref|XP_132325.9| PREDICTED: hypothetical
protein LOC269700 isoform 1 [Mus musculus]
         (4188 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

27369                                                                  96   3e-19
02386                                                                  73   3e-12
05501                                                                  58   7e-08
05524                                                                  57   2e-07
21239                                                                  52   3e-06
33148                                                                  50   2e-05
19738                                                                  37   0.002
32927                                                                  42   0.007
25869                                                                  38   0.11 
18677                                                                  31   8.8  
>27369
          Length = 420

 Score = 96.3 bits (238), Expect = 3e-19,   Method: Compositional matrix adjust.
 Identities = 45/121 (37%), Positives = 80/121 (66%)
 Frame = +1

Query: 1083 FRPSIKEVIQPDVMEEMVVSCVIKHLNLVDALQSLINFQYQEEHAEEYDLLCKIMGETFK 1142
            + P+ +     +++EE V+S V+KHL+L+D ++ L     Q+  +E+Y LL  ++ E ++
Sbjct: 58   YVPASRMYYSQELLEEHVMSVVVKHLSLMDTVRHLSAVAQQQ--SEDYVLLSSVVEEVYR 231

Query: 1143 KLNAMERQLQSVAELEQKWQSEAEDAMQGKLENNMPFFYDYHFNENKMKELELLCSMKEV 1202
            + + + RQLQ++A+LEQ+W++E E+  Q  + +  PFF+DYH  E + KEL +LCS + V
Sbjct: 232  RYDVLLRQLQTMADLEQRWKNEVEEHSQQNVSSTTPFFHDYHLQELRHKELAMLCSXRTV 411

Query: 1203 S 1203
            S
Sbjct: 412  S 414

 Score = 32.0 bits (71), Expect = 5.9,   Method: Composition-based stats.
 Identities = 14/29 (48%), Positives = 19/29 (65%)
 Frame = +3

Query: 1065 PPGIMIKLREISGRARPQFRPSIKEVIQP 1093
            P  IM  LR+++ R   + RPSIK V+QP
Sbjct: 3    PADIMTHLRKLAKRQTLRLRPSIKNVLQP 89
>02386
          Length = 2222

 Score = 72.8 bits (177), Expect = 3e-12,   Method: Compositional matrix adjust.
 Identities = 84/353 (23%), Positives = 137/353 (38%), Gaps = 1/353 (0%)
 Frame = +2

Query: 3828 FNIRFTGEEVHGTSGSFRHFLWQVCKEXXXXXXXXXXXXXXXAVNKNKGKYILTPSP-IT 3886
            F I F GEE     G  R +   + +E                V      Y + PS    
Sbjct: 416  FYIVFEGEEGQDAGGLLREWYLIISREIFNENYVLFKRYPRDGVT-----YTINPSSHFN 580

Query: 3887 YGEEQLLHFLGQLLGIAIRADVPLPLDLLPSFWKTLVGEPLDPDQDLQEADILTYNYVKK 3946
                    F+G+++  AI  +  L      SF+K ++G P+    D++  DI+ Y  +  
Sbjct: 581  SNHLSYFKFVGRIIAKAIYDNKLLECYFTRSFYKHVLGLPVKY-TDMECEDIMFYQSLV- 754

Query: 3947 FESINDESELEALCAEIASQHLATESPEGPKPCCRFTYLTMTGEEVELCSRGRHIPVAWE 4006
            F   ND +++ A   ++        S E  +   R        E  +L   G +I V  E
Sbjct: 755  FLLENDITDMGAALGDLNF------SAEVEEFGVR--------ETRDLIENGSNIGVTEE 892

Query: 4007 NKDIYAAAIRSLRLRELQNMECVTAVRAGLGSIIPLQLLTTLSPLEMELRTCGLPYINLE 4066
            NK  Y   +  +++      + + A   G   IIP +L+   +  E+EL   GLP I+++
Sbjct: 893  NKREYVKLVCQMKMTGAIRQQ-LNAFLEGFYDIIPKKLVAIFTEQELELLISGLPTIDID 1069

Query: 4067 FLKAHTMYQVGLMETDQHIELFWGALEMFTQEELCKFIKFACNQERIPFTCPCKDGGPDT 4126
             LKA+T Y      T   I+ FW AL  F Q E   F++F     ++P        G + 
Sbjct: 1070 DLKANTEYH-KYQPTSLQIQWFWRALRSFDQAERANFLQFVTGTSKVPLQGFATLEGMNG 1246

Query: 4127 AHVPPYPMKIAPPDGTAGPPDSRYIRVETCMFMIKLPQYSSLETMLEKLRCAI 4179
                    +I   D +      R     TC   + LP Y + + + + L  A+
Sbjct: 1247 HQ----KFQIHRDDRST----DRLPSAHTCFNQLDLPAYETYDKLRKMLLLAV 1381
>05501
          Length = 1740

 Score = 58.2 bits (139), Expect = 7e-08,   Method: Compositional matrix adjust.
 Identities = 53/205 (25%), Positives = 81/205 (39%), Gaps = 4/205 (1%)
 Frame = -1

Query: 3979 CCRFTYLTMTGEEVELCSRGRHIPVAWENKDIYAAAIRSLRL-RELQNMECVTAVRAGLG 4037
            C  F  L    E  EL   G  I V  ENK+ Y   +   R  R ++  E   A   G  
Sbjct: 1239 CADFEVLGKV-ENHELKPGGSEIKVTEENKEEYLNLMTQWRFSRGVE--EQTKAFLEGFN 1069

Query: 4038 SIIPLQLLTTLSPLEMELRTCGLPYINLEFLKAHTMYQVGLMETDQHIELFWGALEMFTQ 4097
             ++PLQ L      E+EL  CG+  ++++  + +T+Y+       + +  FW  +     
Sbjct: 1068 EVVPLQWLQYFDERELELMLCGMQEVDVDDWERNTIYR-HYQRNSKQVTWFWKFVREIDN 892

Query: 4098 EELCKFIKFACNQERIP---FTCPCKDGGPDTAHVPPYPMKIAPPDGTAGPPDSRYIRVE 4154
            E+  + ++F     R+P   F       GP    +     +   P            R  
Sbjct: 891  EKRTRLLQFVTGTCRLPVGGFAELMGSNGPQRFCIEKVGKETWLP------------RSH 748

Query: 4155 TCMFMIKLPQYSSLETMLEKLRCAI 4179
            TC   I LP Y S E ++EKL  AI
Sbjct: 747  TCFNRIDLPPYRSYEQLVEKLNLAI 673
>05524
          Length = 2623

 Score = 57.0 bits (136), Expect = 2e-07,   Method: Composition-based stats.
 Identities = 40/124 (32%), Positives = 60/124 (48%)
 Frame = +2

Query: 4058 CGLPYINLEFLKAHTMYQVGLMETDQHIELFWGALEMFTQEELCKFIKFACNQERIPFTC 4117
            CG P I L  LK+   Y+ G+  T   ++ FW  ++ F+  E   F++F   + R+P T 
Sbjct: 491  CGSPDIPLTLLKSVATYK-GIEATAPLVQWFWEVMDEFSTAERSLFLRFVWGRTRLPRTI 667

Query: 4118 PCKDGGPDTAHVPPYPMKIAPPDGTAGPPDSRYIRVETCMFMIKLPQYSSLETMLEKLRC 4177
                G      V     K  PPD     P+S      TC F++K+P+YS    + EKL+ 
Sbjct: 668  ADFRGRDFVLQVLD---KYNPPDHFL--PESY-----TCFFLLKMPRYSDKLVLKEKLKY 817

Query: 4178 AIHY 4181
            AIH+
Sbjct: 818  AIHF 829

 Score = 46.2 bits (108), Expect = 3e-04,   Method: Composition-based stats.
 Identities = 26/64 (40%), Positives = 35/64 (54%)
 Frame = +3

Query: 3874 NKGKYILTPSPITYGEEQLLHFLGQLLGIAIRADVPLPLDLLPSFWKTLVGEPLDPDQDL 3933
            N+  ++L PS  +   + +  FLG L+GIAIR+  PL L +    WK L G PL    DL
Sbjct: 15   NRDCFLLNPSLSSPLHQNMFRFLGILMGIAIRSGSPLSLSIAEPAWKQLAGMPLSI-SDL 191

Query: 3934 QEAD 3937
             E D
Sbjct: 192  TEMD 203
>21239
          Length = 1264

 Score = 52.4 bits (124), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 52/198 (26%), Positives = 78/198 (39%), Gaps = 3/198 (1%)
 Frame = +1

Query: 3984 YLTMTGEEVELCSRGRHIPVAWENKDIYAAAIRSLRLRELQNMECVTAVRAGLGSIIPLQ 4043
            Y  + G  +EL   G+ IPV   N   Y   +    L E  + +   A R G  S+  L 
Sbjct: 94   YFHLPGYNIELKKGGKDIPVTLHNLHEYLQLVIHWSLVEGVSRQ-FEAFREGFESVFSLS 270

Query: 4044 LLTTLSPLEMELRTCGLPY--INLEFLKAHTMYQVGLMETDQHIELFWGALEMFTQEELC 4101
             L    P E+E   CG  +    ++ L  +     G     + +   +  L  F  ++  
Sbjct: 271  SLQCFYPEELEQLFCGSQWGPWEVKMLMENCRPDHGYTHDSKAVVFLYQLLASFDLQQQR 450

Query: 4102 KFIKFACNQERIPFTCPCKDGGPDTAHVPPYPMKIAPPDGTAGP-PDSRYIRVETCMFMI 4160
             F++F     R+P        G   +  PP  + I      AG  PD     V TC+  +
Sbjct: 451  HFLQFVTGSPRLPV-------GGFRSLTPP--LTIVRKTFEAGENPDDFLPSVMTCVNYL 603

Query: 4161 KLPQYSSLETMLEKLRCA 4178
            KLP YSS++ M  KL  A
Sbjct: 604  KLPDYSSIDIMRHKLHTA 657
>33148
          Length = 687

 Score = 50.1 bits (118), Expect = 2e-05,   Method: Composition-based stats.
 Identities = 32/111 (28%), Positives = 47/111 (42%)
 Frame = +3

Query: 4070 AHTMYQVGLMETDQHIELFWGALEMFTQEELCKFIKFACNQERIPFTCPCKDGGPDTAHV 4129
            + T Y   L ETD  ++ FW A++ F+ E+  +F++F   + R+P       G  DT   
Sbjct: 21   SKTTYYDDLEETDIRVKYFWEAMKAFSNEDRSRFLRFVTGRRRLPAPLVISTGKGDTIDS 200

Query: 4130 PPYPMKIAPPDGTAGPPDSRYIRVETCMFMIKLPQYSSLETMLEKLRCAIH 4180
             P                       TC  M+ LP YSS +   EKLR A +
Sbjct: 201  LP--------------------ESSTCANMLYLPYYSSAKVAEEKLRYAAY 293
>19738
          Length = 375

 Score = 36.6 bits (83), Expect(2) = 0.002,   Method: Composition-based stats.
 Identities = 27/80 (33%), Positives = 37/80 (46%)
 Frame = +2

Query: 3992 VELCSRGRHIPVAWENKDIYAAAIRSLRLRELQNMECVTAVRAGLGSIIPLQLLTTLSPL 4051
            VEL   G +I V  +NK  Y   +   RL      E  + +R GL  +IP  LL+     
Sbjct: 5    VELMPGGGNIRVTNKNKLSYLDCLAQYRLATSVKEEVESFLR-GLNELIPDNLLSIFDEY 181

Query: 4052 EMELRTCGLPYINLEFLKAH 4071
            E+EL  CG+   +L   K H
Sbjct: 182  ELELLMCGMGTYSLADFKIH 241

 Score = 25.8 bits (55), Expect(2) = 0.002,   Method: Compositional matrix adjust.
 Identities = 7/33 (21%), Positives = 20/33 (60%)
 Frame = +1

Query: 4082 DQHIELFWGALEMFTQEELCKFIKFACNQERIP 4114
            ++ ++ FW  +  FT+E++ + ++F     ++P
Sbjct: 271  NKVLDWFWTVIASFTEEQMARLLQFTTGCSQLP 369
>32927
          Length = 514

 Score = 41.6 bits (96), Expect = 0.007,   Method: Composition-based stats.
 Identities = 17/37 (45%), Positives = 24/37 (64%)
 Frame = +3

Query: 4145 PPDSRYIRVETCMFMIKLPQYSSLETMLEKLRCAIHY 4181
            PPD       TC F++K+P+YS    +LEKL+ AIH+
Sbjct: 36   PPDHFLPESYTCFFLLKMPRYSCKTVLLEKLKYAIHF 146
>25869
          Length = 438

 Score = 37.7 bits (86), Expect = 0.11,   Method: Compositional matrix adjust.
 Identities = 26/84 (30%), Positives = 40/84 (47%), Gaps = 1/84 (1%)
 Frame = +2

Query: 3872 NKNKGKYILTPSPITYGEEQLLHFLGQLLGIAIRADVPLPLDLLPSF-WKTLVGEPLDPD 3930
            N N+  Y+   S   + +     ++G+L+G   R+   L L L PSF WK LVGE +   
Sbjct: 113  NLNRDVYVPCSSSQDWDK---FEWIGKLMGACFRSKENLVLSL-PSFVWKKLVGEAIAWT 280

Query: 3931 QDLQEADILTYNYVKKFESINDES 3954
            +D Q  D           S+++ES
Sbjct: 281  RDFQSVDSAEVQLTDSISSMDEES 352
>18677
          Length = 754

 Score = 31.2 bits (69), Expect = 8.8,   Method: Compositional matrix adjust.
 Identities = 18/63 (28%), Positives = 28/63 (44%)
 Frame = +2

Query: 1580 LLNDLSRSHIGKAILSQPACVSKLLSLLLDQRPSPKLVLIILQLCRAALPLMSVEDCGNV 1639
             ++D+   H G      P  + K L  + D+    +L   I Q CR+ LP+M     G +
Sbjct: 293  FVSDIFHKHCGSDSRLDPGELQKFLEDVSDEDVKQRLKFNIEQ-CRSLLPMMDENRSGRL 469

Query: 1640 ELP 1642
            E P
Sbjct: 470  EFP 478
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|65301464|ref|NP_034156.2| ArfGAP with SH# domain,
ankyrin repeat and PH domain1 [Mus musculus]
         (1147 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

02351                                                                  94   3e-19
16716                                                                  42   0.002
12324                                                                  41   0.003
02114                                                                  40   0.005
12417                                                                  39   0.011
16561                                                                  35   0.13 
01494                                                                  35   0.13 
28113                                                                  35   0.14 
26032                                                                  33   0.46 
17286                                                                  33   0.56 
21814                                                                  32   1.8  
11295                                                                  30   5.6  
29687                                                                  30   5.9  
15115                                                                  29   9.4  
>02351
          Length = 939

 Score = 94.4 bits (233), Expect = 3e-19,   Method: Composition-based stats.
 Identities = 61/207 (29%), Positives = 90/207 (43%)
 Frame = +3

Query: 465 GNDICCDCGSSEPTWLSTNLGILTCIECSGIHREMGVHISRIQSLELDKLGTSELLLAKN 524
           GN IC DCG+  P+W S NLG + CIEC G+HR +G HISR++SL+LD        +  +
Sbjct: 21  GNTICVDCGTPSPSWASINLGAVMCIECCGVHRNIGTHISRVRSLDLDDWPPEVTKVMTS 200

Query: 525 VGNNSFNDIMEANLXXXXXXXXXXXDMTVRKEYITAKYVDHRFSRKTCASSSAKLNELLE 584
           +GN   N + EAN            +   ++++I AKY    F             +L++
Sbjct: 201 IGNYVANSVWEAN-TKGRSKPTSSSNREEKEQWIKAKYEAKEFLPPLPYIDIPINQQLID 377

Query: 585 AIKSRDLLALIQVYAEGVXXXXXXXXXXXXXXXTALHLAVRTADQTSLHLVDFLVQNCGN 644
           A+   D+  +I +                    TALH+A    +   + L   L+  C N
Sbjct: 378 ALVREDIRNIIIILGHAA-SDDINSPYGKDDGRTALHIAAALGNVVYVQL---LLWYCAN 545

Query: 645 LDKQTSVGNTVLHYCSMYGKPECLKLL 671
           +      G   L Y    G  EC  LL
Sbjct: 546 VKVVDHEGRNALWYARTSGSVECTDLL 626
>16716
          Length = 934

 Score = 41.6 bits (96), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 19/53 (35%), Positives = 26/53 (49%)
 Frame = -1

Query: 1092 TIYDCQADNDDELTFXXXXXXXXXXXXDQEWWIGHIEGQPERKGVFPVSFVHI 1144
             +YD QA +DDELTF            D  WW G   G   + G+FP ++V +
Sbjct: 457  ALYDYQAADDDELTFDPDDVITDIEMIDDGWWRGSCHG---KNGLFPANYVEL 308
>12324
          Length = 946

 Score = 40.8 bits (94), Expect = 0.003,   Method: Composition-based stats.
 Identities = 20/56 (35%), Positives = 29/56 (51%)
 Frame = +3

Query: 1087 VRRVKTIYDCQADNDDELTFXXXXXXXXXXXXDQEWWIGHIEGQPERKGVFPVSFV 1142
            + +V  IYD +A+ DDELTF            D  WW G ++G     G+FP ++V
Sbjct: 687  IEKVVAIYDYEAEKDDELTFSENSVIYVIRKNDDGWWEGVMDGV---TGLFPSNYV 845
>02114
          Length = 1072

 Score = 40.0 bits (92), Expect = 0.005,   Method: Composition-based stats.
 Identities = 28/85 (32%), Positives = 42/85 (49%), Gaps = 1/85 (1%)
 Frame = +1

Query: 621 HLAVRTADQTSLHLVDFLVQN-CGNLDKQTSVGNTVLHYCSMYGKPECLKLLLRSKPTVD 679
           H+A    +   L +   LV+N   N++++   GNT+ H  +  G    L+ L+     V+
Sbjct: 730 HMAAYNGELDHLRI---LVENGVVNINERDDKGNTLAHRAAGQGHLNILQWLVEMGADVE 900

Query: 680 IVNQNGETALDIAKRLKATQCEDLL 704
           I N  GETA DIA+R     C  LL
Sbjct: 901 ISNGAGETARDIARRFAHLACVKLL 975

 Score = 32.0 bits (71), Expect = 1.6,   Method: Composition-based stats.
 Identities = 21/68 (30%), Positives = 33/68 (48%), Gaps = 4/68 (5%)
 Frame = +1

Query: 632 LHLVDFLVQNCGNLDKQTSVGNTVLHYCSMYGKPECLKLLLRSKP----TVDIVNQNGET 687
           L  +  L++     D   + GNT  H  +M G   CLK L+ S+     T+   N +GET
Sbjct: 439 LGCLQMLIKWGARYDDIDTNGNTPAHLAAMEGHLPCLKFLVSSEGCPEHTLGARNDHGET 618

Query: 688 ALDIAKRL 695
             D+A++ 
Sbjct: 619 PRDLAQQF 642
>12417
          Length = 954

 Score = 38.9 bits (89), Expect = 0.011,   Method: Compositional matrix adjust.
 Identities = 20/63 (31%), Positives = 29/63 (46%)
 Frame = +2

Query: 638 LVQNCGNLDKQTSVGNTVLHYCSMYGKPECLKLLLRSKPTVDIVNQNGETALDIAKRLKA 697
           L+Q   +++  T  G T LH  S  G    + LLL     +D  +  G+TAL IA +   
Sbjct: 290 LIQTGADVNSATEHGRTPLHXASAQGHGHIVDLLLEKGADIDAEDDYGDTALSIADQFGF 469

Query: 698 TQC 700
             C
Sbjct: 470 KSC 478
>16561
          Length = 2029

 Score = 35.4 bits (80), Expect = 0.13,   Method: Composition-based stats.
 Identities = 16/53 (30%), Positives = 29/53 (54%)
 Frame = -3

Query: 652  GNTVLHYCSMYGKPECLKLLLRSKPTVDIVNQNGETALDIAKRLKATQCEDLL 704
            G+T LHY +   +P+ L+LLL     ++ +N  G + L +A   +  +C  +L
Sbjct: 2012 GDTALHYSAFGNQPDVLQLLLSKGAKINALNNGGCSTLHVAVNKQHIKCVHVL 1854
>01494
          Length = 2122

 Score = 35.4 bits (80), Expect = 0.13,   Method: Compositional matrix adjust.
 Identities = 18/54 (33%), Positives = 26/54 (48%)
 Frame = +3

Query: 1089 RVKTIYDCQADNDDELTFXXXXXXXXXXXXDQEWWIGHIEGQPERKGVFPVSFV 1142
            RVK ++D  A+ DDEL+F            D  WW G    +  ++  FP +FV
Sbjct: 309  RVKALHDYNANRDDELSFCKGAIITNVSRQDGGWWRGDYGAK--KQHWFPSNFV 464
>28113
          Length = 449

 Score = 35.4 bits (80), Expect = 0.14,   Method: Composition-based stats.
 Identities = 23/88 (26%), Positives = 43/88 (48%)
 Frame = -3

Query: 626 TADQTSLHLVDFLVQNCGNLDKQTSVGNTVLHYCSMYGKPECLKLLLRSKPTVDIVNQNG 685
           +A Q  +H V  L+ +  +  K+ S+    +HY S YG  + +++LL +  + ++ N   
Sbjct: 312 SAAQGDVHHVQSLLNHGHHHSKKDSIAWAAIHYASWYGSADVVEILLDAGCSPNLTNSEL 133

Query: 686 ETALDIAKRLKATQCEDLLSQAKSGKFN 713
            T L IA +       + L QA++   N
Sbjct: 132 LTPLHIAAKKGFPDVAEHLVQAEAIDLN 49
>26032
          Length = 465

 Score = 33.5 bits (75), Expect = 0.46,   Method: Composition-based stats.
 Identities = 17/53 (32%), Positives = 24/53 (45%)
 Frame = +2

Query: 1095 DCQADNDDELTFXXXXXXXXXXXXDQEWWIGHIEGQPERKGVFPVSFVHILSD 1147
            D +  +DDEL F            D+  WIG + G    +G FP  FV +L +
Sbjct: 29   DFERHDDDELGFRKNDIITLISQKDEHCWIGELNGL---RGWFPAKFVEVLDE 178
>17286
          Length = 489

 Score = 33.5 bits (75), Expect = 0.56,   Method: Composition-based stats.
 Identities = 15/55 (27%), Positives = 27/55 (49%)
 Frame = +3

Query: 1091 KTIYDCQADNDDELTFXXXXXXXXXXXXDQEWWIGHIEGQPERKGVFPVSFVHIL 1145
            + IYD   ++D EL F            D+ W+ G + G   + G FP+++V ++
Sbjct: 33   RAIYDFLPESDGELGFQEGDMITLISQVDENWFEGSVHG---KVGYFPINYVEVV 188
>21814
          Length = 415

 Score = 31.6 bits (70), Expect = 1.8,   Method: Composition-based stats.
 Identities = 16/54 (29%), Positives = 28/54 (51%), Gaps = 2/54 (3%)
 Frame = +3

Query: 395 EDKKSFDLISHNRTYHFQAEDEQDYIAWISVLTNS--KEEALTMAFRGEQSTGE 446
           ED  +F +   ++T+HFQA D  +   WI+ L  +  ++   T   RG+  + E
Sbjct: 42  EDDSTFTITVDHKTFHFQARDGDERERWINALQRAIDRQHFSTAGVRGQLVSPE 203
>11295
          Length = 1179

 Score = 30.0 bits (66), Expect = 5.6,   Method: Composition-based stats.
 Identities = 20/61 (32%), Positives = 30/61 (49%)
 Frame = +1

Query: 654 TVLHYCSMYGKPECLKLLLRSKPTVDIVNQNGETALDIAKRLKATQCEDLLSQAKSGKFN 713
           T LHY S  G    L+LLL+ K   ++V+  G T L IA         ++L Q+ +  + 
Sbjct: 679 TPLHYISRRGHLTMLQLLLQGKAEPNVVDDEGITPLYIASCEGHVTIVNILLQSGAKIYM 858

Query: 714 P 714
           P
Sbjct: 859 P 861
>29687
          Length = 434

 Score = 30.0 bits (66), Expect = 5.9,   Method: Compositional matrix adjust.
 Identities = 16/54 (29%), Positives = 26/54 (48%)
 Frame = -2

Query: 1089 RVKTIYDCQADNDDELTFXXXXXXXXXXXXDQEWWIGHIEGQPERKGVFPVSFV 1142
            RVK ++D  A  +DEL+F            D  WW G  +   +++  FP ++V
Sbjct: 295  RVKALHDYNAKREDELSFCKGAIITNVSRQDGGWWRG--DYGTKKQHWFPSNYV 140
>15115
          Length = 443

 Score = 29.3 bits (64), Expect = 9.4,   Method: Composition-based stats.
 Identities = 16/50 (32%), Positives = 24/50 (48%), Gaps = 1/50 (2%)
 Frame = -2

Query: 1097 QADNDDELTFXXXXXXXXXXXXDQEWWIGHIEGQPERK-GVFPVSFVHIL 1145
            QA +D E+TF            D+ WW G     P+   G+FP ++V +L
Sbjct: 430  QAGDDTEITFDPDDIITNIDQIDEGWWQGF---APDGSYGMFPANYVELL 290
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6680083|ref|NP_032189.1| growth factor receptor bound
protein 2 [Mus musculus]
         (217 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

11780                                                                  91   3e-19
29243                                                                  64   3e-11
17286                                                                  64   5e-11
11228                                                                  63   9e-11
16716                                                                  55   3e-08
12324                                                                  55   3e-08
14257                                                                  48   3e-06
06405                                                                  44   6e-05
20131                                                                  43   9e-05
29636                                                                  42   2e-04
06462                                                                  42   2e-04
26032                                                                  42   3e-04
19469                                                                  41   4e-04
31183                                                                  41   4e-04
13664                                                                  40   5e-04
30740                                                                  40   7e-04
13641                                                                  39   0.001
10546                                                                  39   0.002
28095                                                                  38   0.003
00341                                                                  38   0.003
08480                                                                  38   0.003
15115                                                                  37   0.006
18881                                                                  37   0.006
37260                                                                  34   0.045
01494                                                                  33   0.078
04627                                                                  33   0.12 
30231                                                                  32   0.15 
29687                                                                  32   0.22 
21187                                                                  31   0.43 
18050                                                                  30   0.77 
33143                                                                  30   0.96 
17679                                                                  29   1.7  
>11780
          Length = 1713

 Score = 90.9 bits (224), Expect = 3e-19,   Method: Compositional matrix adjust.
 Identities = 45/100 (45%), Positives = 65/100 (65%), Gaps = 7/100 (7%)
 Frame = +3

Query: 19  FKRGDILKVLNEECDQNWYKA-ELNGKDGFIPKNYIE------MKPHPWFFGKIPRAKAE 71
           F++GD+L +     D+ WYKA + NG++G IP NY++      +   PWF GKI R +AE
Sbjct: 111 FQKGDLLVIRRATSDRMWYKACDSNGREGMIPANYVQPRKVVTLHAMPWFHGKITRQQAE 290

Query: 72  EMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVL 111
           E+L K R DG FLIRES + PGD++L V     V+H+++L
Sbjct: 291 ELL-KPREDGLFLIRESSNYPGDYTLCVCHLGKVEHYRIL 407
>29243
          Length = 1147

 Score = 64.3 bits (155), Expect = 3e-11,   Method: Compositional matrix adjust.
 Identities = 45/172 (26%), Positives = 83/172 (48%), Gaps = 14/172 (8%)
 Frame = +2

Query: 53  IEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESA--PGDFSLSVKFGNDVQHFKV 110
             ++ + W+ G + R  A++ L     DG FLIR + +    G+ SLS+K+ N V+H KV
Sbjct: 287 CSLESYNWYVGIMERPVAQKXLDTC-PDGTFLIRVTNNPLRRGELSLSIKYANAVRHIKV 463

Query: 111 LRDGAGKYFLWVVK-FNSLNELVDYHRSTS-------VSRNQQIFLRDIEQMPQQPTYVQ 162
            R+  G+++L   + F+++  LVD++ +         V+   +   +D+        +  
Sbjct: 464 NRNPQGRFYLADGRYFDNIQSLVDHYENNELADSFPDVTTTLRFPYKDVATXACILGFAV 643

Query: 163 ALFDFDPQEDGELGFRRGDFIHVM--DNSDPNWWKGAC--HGQTGMFPRNYV 210
           A++D+      +L  +  D I ++  +  D  WWKG      + G FP  YV
Sbjct: 644 AVYDYAATSTSQLSMKLNDRIAILSKNGQDKGWWKGENLRTQKIGYFPLAYV 799
>17286
          Length = 489

 Score = 63.9 bits (154), Expect = 5e-11,   Method: Compositional matrix adjust.
 Identities = 28/58 (48%), Positives = 40/58 (68%)
 Frame = +3

Query: 156 QQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPV 213
           +QP   +A++DF P+ DGELGF+ GD I ++   D NW++G+ HG+ G FP NYV  V
Sbjct: 18  KQPC-ARAIYDFLPESDGELGFQEGDMITLISQVDENWFEGSVHGKVGYFPINYVEVV 188

 Score = 50.4 bits (119), Expect = 5e-07,   Method: Compositional matrix adjust.
 Identities = 21/53 (39%), Positives = 37/53 (69%)
 Frame = +3

Query: 3  AIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEM 55
          A A YDF   +D EL F+ GD++ ++++  D+NW++  ++GK G+ P NY+E+
Sbjct: 30 ARAIYDFLPESDGELGFQEGDMITLISQ-VDENWFEGSVHGKVGYFPINYVEV 185
>11228
          Length = 2155

 Score = 62.8 bits (151), Expect = 9e-11,   Method: Compositional matrix adjust.
 Identities = 42/132 (31%), Positives = 71/132 (53%), Gaps = 9/132 (6%)
 Frame = -2

Query: 10   KATADDELSFKRGDILKVLNEECDQ-NWYKAELNGKDGFIPKNYIE--------MKPHPW 60
            KAT  DELSF +GD+  V NE  D   W   E   + G +P  +++        ++  P+
Sbjct: 1641 KATDSDELSFCKGDVFVVQNEMEDGWLWVTCERTKESGLVPAPFVKDLDGDYEPVESLPY 1462

Query: 61   FFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFL 120
            F   + + +A E L     +G+FL+R+SE+ PGD+SL      DV+ F++ R G  ++ +
Sbjct: 1461 FHSCLSKEEAVEKLMLA-GEGSFLVRQSENYPGDYSLFFLCEKDVRRFRIERRG-NQFLV 1288

Query: 121  WVVKFNSLNELV 132
                F+SL+ ++
Sbjct: 1287 GGRLFDSLDGVI 1252

 Score = 40.4 bits (93), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 20/39 (51%), Positives = 27/39 (69%)
 Frame = -1

Query: 60   WFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLS 98
            W+ G++ RA AEE+L  Q   G++L+RESES  G F LS
Sbjct: 1972 WYHGRLGRAGAEELLRDQ-DAGSYLVRESESKLGSFVLS 1859
>16716
          Length = 934

 Score = 54.7 bits (130), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 22/48 (45%), Positives = 31/48 (64%)
 Frame = -1

Query: 163 ALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYV 210
           AL+D+   +D EL F   D I  ++  D  WW+G+CHG+ G+FP NYV
Sbjct: 457 ALYDYQAADDDELTFDPDDVITDIEMIDDGWWRGSCHGKNGLFPANYV 314

 Score = 48.9 bits (115), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 22/54 (40%), Positives = 35/54 (64%)
 Frame = -1

Query: 3   AIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMK 56
           AIA YD++A  DDEL+F   D++  + E  D  W++   +GK+G  P NY+E++
Sbjct: 463 AIALYDYQAADDDELTFDPDDVITDI-EMIDDGWWRGSCHGKNGLFPANYVELQ 305
>12324
          Length = 946

 Score = 54.7 bits (130), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 28/70 (40%), Positives = 41/70 (58%), Gaps = 3/70 (4%)
 Frame = +3

Query: 147 FLRDIEQMPQQPTYVQ---ALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTG 203
           FL   E MP   TY++   A++D++ ++D EL F     I+V+  +D  WW+G   G TG
Sbjct: 651 FLGPDEYMPA--TYIEKVVAIYDYEAEKDDELTFSENSVIYVIRKNDDGWWEGVMDGVTG 824

Query: 204 MFPRNYVTPV 213
           +FP NYV P 
Sbjct: 825 LFPSNYVEPC 854

 Score = 44.7 bits (104), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 18/51 (35%), Positives = 31/51 (60%)
 Frame = +3

Query: 4   IAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIE 54
           +A YD++A  DDEL+F    ++ V+ +  D  W++  ++G  G  P NY+E
Sbjct: 699 VAIYDYEAEKDDELTFSENSVIYVIRKN-DDGWWEGVMDGVTGLFPSNYVE 848
>14257
          Length = 919

 Score = 47.8 bits (112), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 28/81 (34%), Positives = 47/81 (58%)
 Frame = -3

Query: 60  WFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYF 119
           W+ GKI R +AE++L     DG FL+RE+ ++   F LS +   +V+H  +L D  G   
Sbjct: 890 WYHGKIGRKEAEKLLEL---DGDFLVREASNSAAQFVLSGRQNGNVRHL-LLVDPDGIVR 723

Query: 120 LWVVKFNSLNELVDYHRSTSV 140
                F+S++ L++YHR  ++
Sbjct: 722 TKDFIFDSVSHLINYHRQNAL 660
>06405
          Length = 1965

 Score = 43.5 bits (101), Expect = 6e-05,   Method: Compositional matrix adjust.
 Identities = 20/49 (40%), Positives = 30/49 (61%)
 Frame = +1

Query: 87  ESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYH 135
           ESES+PG  S+SV+F   V H+++  D    +     +FN+L ELV +H
Sbjct: 1   ESESSPGQRSISVRFEGRVYHYRITEDDGKVFVTQEHRFNTLAELVHHH 147
>20131
          Length = 574

 Score = 43.1 bits (100), Expect = 9e-05,   Method: Compositional matrix adjust.
 Identities = 21/54 (38%), Positives = 27/54 (50%)
 Frame = -2

Query: 160 YVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPV 213
           Y  A++ +   E  +L F  GD I V    D +WW G    +TGMFP  YV  V
Sbjct: 477 YYVAMYSYVSGETADLTFNEGDMILVTKK-DEDWWTGTLGEKTGMFPSTYVKKV 319

 Score = 39.7 bits (91), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 20/81 (24%), Positives = 34/81 (41%), Gaps = 10/81 (12%)
 Frame = -2

Query: 146 IFLRDIEQMPQQ-----PTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHG 200
            +++ +E  P Q     P     +  +    +G+L    G+ IHV   S   WW+G    
Sbjct: 336 TYVKKVEIQPGQKSAKKPEIAMVIAPYTATGNGQLSLEPGNLIHVRQKSPRGWWEGELQA 157

Query: 201 -----QTGMFPRNYVTPVNRN 216
                + G FP +YV P+  +
Sbjct: 156 RGQRKKIGWFPADYVKPLGSS 94
>29636
          Length = 354

 Score = 42.0 bits (97), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 23/71 (32%), Positives = 37/71 (52%), Gaps = 12/71 (16%)
 Frame = +1

Query: 148 LRDIEQMPQQPTYVQALFDFDPQEDG-----ELG--FRRGDFIHVMDNSDPNWWKGACHG 200
           + D    P    +++ALF++DP++D      ELG  F +GD +H +  SD NWW+    G
Sbjct: 37  VEDTTAKPGDIMHLRALFNYDPEDDPYIPCRELGISFLKGDILHAIQLSDSNWWQAHREG 216

Query: 201 Q-----TGMFP 206
           +      G+ P
Sbjct: 217 EDAHMLAGLIP 249

 Score = 27.7 bits (60), Expect = 3.5,   Method: Compositional matrix adjust.
 Identities = 14/40 (35%), Positives = 22/40 (55%)
 Frame = +1

Query: 17  LSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMK 56
           +SF +GDIL  + +  D NW++A   G+D  +    I  K
Sbjct: 139 ISFLKGDILHAI-QLSDSNWWQAHREGEDAHMLAGLIPSK 255
>06462
          Length = 1511

 Score = 41.6 bits (96), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 28/76 (36%), Positives = 39/76 (51%)
 Frame = +1

Query: 60   WFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYF 119
            W+ GK+ R +AE++L K   DG FL+RES      F LS K      H  +L D  G   
Sbjct: 1096 WYHGKMSRREAEKLLGK---DGDFLVRESGHNXSQFVLSGKHHGQFIHL-LLVDPDGIVR 1263

Query: 120  LWVVKFNSLNELVDYH 135
                 F++++ LV YH
Sbjct: 1264 TKDYIFDNISHLVSYH 1311
>26032
          Length = 465

 Score = 41.6 bits (96), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 18/49 (36%), Positives = 28/49 (57%)
 Frame = +2

Query: 166 DFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVN 214
           DF+  +D ELGFR+ D I ++   D + W G  +G  G FP  +V  ++
Sbjct: 29  DFERHDDDELGFRKNDIITLISQKDEHCWIGELNGLRGWFPAKFVEVLD 175

 Score = 38.5 bits (88), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 17/48 (35%), Positives = 33/48 (68%)
 Frame = +2

Query: 8  DFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEM 55
          DF+   DDEL F++ DI+ +++++ D++ +  ELNG  G+ P  ++E+
Sbjct: 29 DFERHDDDELGFRKNDIITLISQK-DEHCWIGELNGLRGWFPAKFVEV 169
>19469
          Length = 428

 Score = 41.2 bits (95), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 19/55 (34%), Positives = 31/55 (56%), Gaps = 2/55 (3%)
 Frame = -1

Query: 3   AIAKYDFKATADDELSFKRGDILKVLNEECD--QNWYKAELNGKDGFIPKNYIEM 55
           A A YD  A   DEL+F+RGD++ +L ++      W+   L G+ G  P N +++
Sbjct: 359 AKALYDNIAETPDELAFRRGDVITILEQDTAGLDGWWLCSLRGRQGIAPGNRLKI 195

 Score = 36.2 bits (82), Expect = 0.011,   Method: Compositional matrix adjust.
 Identities = 17/50 (34%), Positives = 26/50 (52%), Gaps = 3/50 (6%)
 Frame = -1

Query: 162 QALFDFDPQEDGELGFRRGDFIHVMDNSDP---NWWKGACHGQTGMFPRN 208
           +AL+D   +   EL FRRGD I +++        WW  +  G+ G+ P N
Sbjct: 356 KALYDNIAETPDELAFRRGDVITILEQDTAGLDGWWLCSLRGRQGIAPGN 207
>31183
          Length = 923

 Score = 40.8 bits (94), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 15/30 (50%), Positives = 21/30 (70%)
 Frame = +1

Query: 181 DFIHVMDNSDPNWWKGACHGQTGMFPRNYV 210
           D I  ++  D  WW+G+CHG+ G+FP NYV
Sbjct: 4   DVITDIEMIDDGWWRGSCHGKNGLFPANYV 93

 Score = 31.2 bits (69), Expect = 0.36,   Method: Compositional matrix adjust.
 Identities = 10/27 (37%), Positives = 17/27 (62%)
 Frame = +1

Query: 30 EECDQNWYKAELNGKDGFIPKNYIEMK 56
          E  D  W++   +GK+G  P NY+E++
Sbjct: 22 EMIDDGWWRGSCHGKNGLFPANYVELQ 102
>13664
          Length = 507

 Score = 40.4 bits (93), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 16/46 (34%), Positives = 29/46 (63%)
 Frame = +2

Query: 2   EAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGF 47
           + +A YD+KA   DEL+   GD++ +L+++ +  W    L+G+ GF
Sbjct: 368 KVVALYDYKAQRSDELTILSGDVIMLLHKDSESWWMGELLDGQQGF 505

 Score = 33.9 bits (76), Expect = 0.050,   Method: Compositional matrix adjust.
 Identities = 17/49 (34%), Positives = 24/49 (48%), Gaps = 1/49 (2%)
 Frame = +2

Query: 156 QQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKG-ACHGQTG 203
           ++P  V AL+D+  Q   EL    GD I ++     +WW G    GQ G
Sbjct: 356 RKPKKVVALYDYKAQRSDELTILSGDVIMLLHKDSESWWMGELLDGQQG 502
>30740
          Length = 488

 Score = 40.0 bits (92), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 29/128 (22%), Positives = 57/128 (44%), Gaps = 4/128 (3%)
 Frame = +2

Query: 94  DFSLSVKFGNDVQHFKVLR---DGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRD 150
           DF L VK  + V H+ + R    G  ++ +   +FN +  L+++++S  +     I    
Sbjct: 2   DFVLCVKEDSKVSHYIINRIQVGGLTRFKIGDKEFNDIPSLLNFYKSHYLDTTTLI---- 169

Query: 151 IEQMPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGA-CHGQTGMFPRNY 209
               P     +   +DF  ++  +L F +GD + ++   +  WW     HG+ G  P + 
Sbjct: 170 ---RPAPREKLMGKYDFSGRDPEDLPFSKGDILELISKDEEEWWTARDKHGRVGQDPLSS 340

Query: 210 VTPVNRNV 217
              V R++
Sbjct: 341 TPHVFRSL 364

 Score = 32.7 bits (73), Expect = 0.11,   Method: Compositional matrix adjust.
 Identities = 16/55 (29%), Positives = 32/55 (58%)
 Frame = +2

Query: 4   IAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPH 58
           + KYDF     ++L F +GDIL++++++ ++ W   + +G+ G  P   +   PH
Sbjct: 194 MGKYDFSGRDPEDLPFSKGDILELISKDEEEWWTARDKHGRVGQDP---LSSTPH 349
>13641
          Length = 2081

 Score = 39.3 bits (90), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 19/61 (31%), Positives = 34/61 (55%), Gaps = 12/61 (19%)
 Frame = +2

Query: 161 VQALFDFD-------PQEDGELGFRRGDFIHVMDNSDPNWWKGACHG----QTGMFP-RN 208
           V+A+F F+       P ++  L F++GD +H+++  D  WW+   HG    + G+ P R+
Sbjct: 158 VKAMFSFNSKLDDNIPCKEAGLSFQQGDILHIVNQEDAIWWQAYKHGDAKKRAGLIPSRH 337

Query: 209 Y 209
           Y
Sbjct: 338 Y 340

 Score = 32.0 bits (71), Expect = 0.19,   Method: Compositional matrix adjust.
 Identities = 21/63 (33%), Positives = 33/63 (52%), Gaps = 11/63 (17%)
 Frame = +2

Query: 1   MEAIAKYDFKATADDE-------LSFKRGDILKVLNEECDQNWYKAELNG----KDGFIP 49
           M   A + F +  DD        LSF++GDIL ++N+E D  W++A  +G    + G IP
Sbjct: 152 MVVKAMFSFNSKLDDNIPCKEAGLSFQQGDILHIVNQE-DAIWWQAYKHGDAKKRAGLIP 328

Query: 50  KNY 52
             +
Sbjct: 329 SRH 337
>10546
          Length = 790

 Score = 38.5 bits (88), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 29/117 (24%), Positives = 56/117 (47%), Gaps = 12/117 (10%)
 Frame = +2

Query: 60  WFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPG-DFSLSVKFGNDVQHFKVLRDGAGKY 118
           W+ G I R+K E ++     DG FL+R S+  P   ++L V     V + ++      K 
Sbjct: 326 WYHGHIERSKGENLVKHVGKDGTFLVRVSDKDPKFPYTLVVYHKGSVNNLRIRLRPDDKV 505

Query: 119 FL-----WVVKFNSLNELVDYHRSTSVSR--NQQIFLRDIEQMPQQ----PTYVQAL 164
            L       + F  +  ++++H+  +V    N Q  ++ ++ MPQ+    PT++ A+
Sbjct: 506 ALGDEKKGEIAFQDVAAMIEHHKQNNVVLLGNNQSQVK-LQHMPQKS*VPPTHLSAV 673
>28095
          Length = 597

 Score = 38.1 bits (87), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 20/56 (35%), Positives = 30/56 (53%), Gaps = 2/56 (3%)
 Frame = +3

Query: 1   MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWY--KAELNGKDGFIPKNYIE 54
           M   A YD++A   DE+SF  GD + +  +  D  W   + E  G+ G +P NY+E
Sbjct: 258 MVCKAMYDYQAADSDEVSFNDGDTI-IECQPVDAGWMTGRVERTGQYGMLPSNYVE 422
>00341
          Length = 1915

 Score = 38.1 bits (87), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 21/61 (34%), Positives = 30/61 (49%)
 Frame = -1

Query: 8    DFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPR 67
            D++A    EL+F  GDIL V  E     +Y  E NG+ G +P  ++E   H     + P 
Sbjct: 1804 DYRAC---ELAFHAGDILLVYGEARQDGFYHGERNGQRGLVPACFVEPVVHGAKSSQKPS 1634

Query: 68   A 68
            A
Sbjct: 1633 A 1631
>08480
          Length = 698

 Score = 38.1 bits (87), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 17/46 (36%), Positives = 27/46 (58%), Gaps = 5/46 (10%)
 Frame = -1

Query: 156 QQPTYVQALFDFDPQEDGELG-----FRRGDFIHVMDNSDPNWWKG 196
           ++  +V+ALFD++P +D  L      F  GD +HV + SD  WW+ 
Sbjct: 461 KRTMFVRALFDYEPSKDSGLPSRGLWFHYGDILHVTNASDDEWWQA 324
>15115
          Length = 443

 Score = 37.0 bits (84), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 19/41 (46%), Positives = 23/41 (56%), Gaps = 1/41 (2%)
 Frame = -2

Query: 171 EDGELGFRRGDFIHVMDNSDPNWWKG-ACHGQTGMFPRNYV 210
           +D E+ F   D I  +D  D  WW+G A  G  GMFP NYV
Sbjct: 421 DDTEITFDPDDIITNIDQIDEGWWQGFAPDGSYGMFPANYV 299
>18881
          Length = 762

 Score = 37.0 bits (84), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 35/143 (24%), Positives = 66/143 (46%), Gaps = 12/143 (8%)
 Frame = -3

Query: 80  DGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVK-FNSLNELVDYHRST 138
           DG FLIR + ++  +      + N V+H KV R+  G+++L     F+S+ +LV+++   
Sbjct: 745 DGTFLIRVTNTSARESCPQY*YANAVRHIKVNRNPQGRFYLADGHYFDSVQQLVEHYEKN 566

Query: 139 S-------VSRNQQIFLRDIEQMPQQPTYVQALFDFDPQEDGELGFRRGDFIHVM--DNS 189
                   V+   +I  + +    +   Y  A++D+      ++  +  D I ++  +  
Sbjct: 565 ELVDSFPDVATTLRIPYKTVASGVRILGYAIAVYDYAATSTTQVTLKLNDRISILSKNGQ 386

Query: 190 DPNWWKGAC--HGQTGMFPRNYV 210
           D  WWKG      + G FP  YV
Sbjct: 385 DKGWWKGENLRTKKVGYFPLAYV 317
>37260
          Length = 401

 Score = 33.9 bits (76), Expect = 0.045,   Method: Compositional matrix adjust.
 Identities = 19/57 (33%), Positives = 32/57 (56%)
 Frame = -1

Query: 54  EMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKV 110
           ++K   W++G +   +AE  L  +R DG+FL+R+S +     SLS K    V H ++
Sbjct: 200 QLKDCGWYWGPLSYEEAESKLMDKR-DGSFLVRDSSNENYILSLSFKSMGHVHHTRI 33
>01494
          Length = 2122

 Score = 33.1 bits (74), Expect = 0.078,   Method: Compositional matrix adjust.
 Identities = 17/51 (33%), Positives = 30/51 (58%), Gaps = 1/51 (1%)
 Frame = +3

Query: 5   AKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNG-KDGFIPKNYIE 54
           A +D+ A  DDELSF +G I+  ++ + D  W++ +    K  + P N++E
Sbjct: 318 ALHDYNANRDDELSFCKGAIITNVSRQ-DGGWWRGDYGAKKQHWFPSNFVE 467
>04627
          Length = 572

 Score = 32.7 bits (73), Expect = 0.12,   Method: Compositional matrix adjust.
 Identities = 16/52 (30%), Positives = 27/52 (51%), Gaps = 1/52 (1%)
 Frame = +3

Query: 60  WFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPG-DFSLSVKFGNDVQHFKV 110
           W+ G I R+K E ++     DG FL+R S+  P   ++L V     V + ++
Sbjct: 357 WYHGHIERSKGENLVKHVGKDGTFLVRVSDKDPKFPYTLVVYHKGSVNNLRI 512
>30231
          Length = 340

 Score = 32.3 bits (72), Expect = 0.15,   Method: Compositional matrix adjust.
 Identities = 14/38 (36%), Positives = 23/38 (60%)
 Frame = -2

Query: 80  DGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGK 117
           DG+FL+R+SES    + L + F   V  +++L D  G+
Sbjct: 252 DGSFLVRDSESVSNAYVLCLLFQLRVHQYRILPDKDGR 139
>29687
          Length = 434

 Score = 32.0 bits (71), Expect = 0.22,   Method: Compositional matrix adjust.
 Identities = 17/55 (30%), Positives = 31/55 (56%), Gaps = 1/55 (1%)
 Frame = -2

Query: 1   MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAEL-NGKDGFIPKNYIE 54
           +   A +D+ A  +DELSF +G I+  ++ + D  W++ +    K  + P NY+E
Sbjct: 298 LRVKALHDYNAKREDELSFCKGAIITNVSRQ-DGGWWRGDYGTKKQHWFPSNYVE 137
>21187
          Length = 1206

 Score = 30.8 bits (68), Expect = 0.43,   Method: Compositional matrix adjust.
 Identities = 14/46 (30%), Positives = 23/46 (50%), Gaps = 3/46 (6%)
 Frame = +2

Query: 175 LGFRRGDFIHVMDNSD---PNWWKGACHGQTGMFPRNYVTPVNRNV 217
           L   RGD + +   S    P+ W G  +G+ G FP+ +V   + N+
Sbjct: 173 LTLNRGDIVEIKSKSAGNRPDLWGGEVNGRKGYFPKAFVKEFHINI 310
>18050
          Length = 448

 Score = 30.0 bits (66), Expect = 0.77,   Method: Compositional matrix adjust.
 Identities = 17/55 (30%), Positives = 30/55 (54%), Gaps = 2/55 (3%)
 Frame = +3

Query: 2  EAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAE--LNGKDGFIPKNYIE 54
          + IAK+ +++   D L  + GD++ V  +  D  WY+ E   +G  G+ P +Y E
Sbjct: 21 QVIAKHSYESDEPDVLQLELGDVVNVSRKLPD-GWYQGERIRDGAVGWFPGSYTE 182
>33143
          Length = 1469

 Score = 29.6 bits (65), Expect = 0.96,   Method: Compositional matrix adjust.
 Identities = 14/47 (29%), Positives = 23/47 (48%), Gaps = 3/47 (6%)
 Frame = -2

Query: 174 ELGFRRGDFIHVMD---NSDPNWWKGACHGQTGMFPRNYVTPVNRNV 217
           E+  + GDF+ V+D   +    WW+G    + G FP + V  +   V
Sbjct: 391 EISLQVGDFVSVIDMPSSEGTKWWRGKKGFEVGFFPADCVEVIRDKV 251
>17679
          Length = 509

 Score = 28.9 bits (63), Expect = 1.7,   Method: Compositional matrix adjust.
 Identities = 10/27 (37%), Positives = 12/27 (44%)
 Frame = -3

Query: 187 DNSDPNWWKGACHGQTGMFPRNYVTPV 213
              DP WW G CH    + PR    P+
Sbjct: 333 SGPDPIWWSGGCHSSPLVVPRKTRAPL 253
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6680231|ref|NP_032279.1| high mobility group box 3
[Mus musculus]
         (200 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

11933                                                                  91   4e-19
33187                                                                  65   3e-11
24607                                                                  47   7e-06
14405                                                                  43   9e-05
21088                                                                  33   0.077
18345                                                                  29   1.3  
>11933
          Length = 1516

 Score = 90.5 bits (223), Expect = 4e-19,   Method: Compositional matrix adjust.
 Identities = 52/157 (33%), Positives = 82/157 (52%)
 Frame = +2

Query: 5   DPKKPKGKMSAYAFFVQTCREEHKKKNPEVPVNFAEFSKKCSERWKTMSSKEKSKFDEMA 64
           D  KPK   SAY +F+  CRE   K+   +    AEF+K+CS +W+ M   +K  F+E A
Sbjct: 632 DANKPKRSTSAYXYFLAHCREVSAKQGKTIS-RIAEFTKECSAKWREMGGAQKKPFEESA 808

Query: 65  KADKVRYDREMXXXXXXXXXXXXXXXXXXXXXXSGFFLFCSEFRPKIKSTNPGISIGDVA 124
             DK RYD+EM                      + +FLF  +FR K+K  N G+   ++ 
Sbjct: 809 AKDKARYDKEM-----ALYKGKSTDPNKPKRPMTAYFLFLGDFRIKMK--NRGVDHKEIL 967

Query: 125 KKLGEMWNNLSDNEKQPYVTKAAKLKEKYEKDVADYK 161
           +  GE W N+S  +K+PY  ++ +  +KYE ++ +Y+
Sbjct: 968 RLAGEEWRNMSAEDKKPYEKRSVEAGKKYEVEMEEYR 1078
>33187
          Length = 644

 Score = 64.7 bits (156), Expect = 3e-11,   Method: Compositional matrix adjust.
 Identities = 28/69 (40%), Positives = 46/69 (66%)
 Frame = +3

Query: 98  SGFFLFCSEFRPKIKSTNPGISIGDVAKKLGEMWNNLSDNEKQPYVTKAAKLKEKYEKDV 157
           S FF FC++ R K+K+ NP   +GD+AK+LG  W+++    KQ Y + A + K +YE+++
Sbjct: 111 SAFFWFCNDERNKVKALNPEFGVGDIAKELGRKWSDVDPEVKQKYESMAERDKARYEREM 290

Query: 158 ADYKSKGKF 166
            +YK+ GK 
Sbjct: 291 TEYKTSGKI 317

 Score = 48.1 bits (113), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 26/71 (36%), Positives = 40/71 (56%)
 Frame = +3

Query: 5   DPKKPKGKMSAYAFFVQTCREEHKKKNPEVPVNFAEFSKKCSERWKTMSSKEKSKFDEMA 64
           DP  PK  +SA+ +F    R + K  NPE  V   + +K+   +W  +  + K K++ MA
Sbjct: 84  DPNAPKRSLSAFFWFCNDERNKVKALNPEFGV--GDIAKELGRKWSDVDPEVKQKYESMA 257

Query: 65  KADKVRYDREM 75
           + DK RY+REM
Sbjct: 258 ERDKARYEREM 290
>24607
          Length = 1354

 Score = 46.6 bits (109), Expect = 7e-06,   Method: Compositional matrix adjust.
 Identities = 18/52 (34%), Positives = 31/52 (59%)
 Frame = -2

Query: 98  SGFFLFCSEFRPKIKSTNPGISIGDVAKKLGEMWNNLSDNEKQPYVTKAAKL 149
           + + L+C+  RPK+ + +PGI    +++ LG MW  LS  EK  +  K+ K+
Sbjct: 381 TAYMLYCNSQRPKVVAESPGIDFAQISRTLGVMWQCLSKKEKMMWRRKSKKM 226
>14405
          Length = 600

 Score = 42.7 bits (99), Expect = 9e-05,   Method: Compositional matrix adjust.
 Identities = 14/38 (36%), Positives = 24/38 (63%)
 Frame = -2

Query: 98  SGFFLFCSEFRPKIKSTNPGISIGDVAKKLGEMWNNLS 135
           + + L+C+  RPK+ + +PGI    +++ LG MW  LS
Sbjct: 242 TAYMLYCNSQRPKVVAESPGIDFAQISRTLGVMWQCLS 129
>21088
          Length = 490

 Score = 33.1 bits (74), Expect = 0.077,   Method: Compositional matrix adjust.
 Identities = 15/64 (23%), Positives = 31/64 (48%)
 Frame = -3

Query: 98  SGFFLFCSEFRPKIKSTNPGISIGDVAKKLGEMWNNLSDNEKQPYVTKAAKLKEKYEKDV 157
           + F +F    R ++ +  P +    ++K LG++W       + PY   A  LK+ + ++ 
Sbjct: 314 NAFMVFAKMERRQMMAAQPELHNARISKHLGDVWRQCPQPLQDPYKQLAQCLKDLHRQEH 135

Query: 158 ADYK 161
            +YK
Sbjct: 134 PEYK 123
>18345
          Length = 461

 Score = 28.9 bits (63), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 13/48 (27%), Positives = 26/48 (54%)
 Frame = +1

Query: 110 KIKSTNPGISIGDVAKKLGEMWNNLSDNEKQPYVTKAAKLKEKYEKDV 157
           ++ ST P + + +V +   +++   +DN   P VTKA ++   Y  +V
Sbjct: 256 RVGSTGPVLVMYNVTRHCDDIYECYADNGVPPAVTKAIRVTVDYAPEV 399
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|86262151|ref|NP_033836.2| Rho GTPase activating
protein 5 [Mus musculus]
         (1503 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

17558                                                                  94   4e-19
17428                                                                  87   5e-17
12558                                                                  72   2e-12
30765                                                                  69   1e-11
20879                                                                  63   1e-09
02134                                                                  57   5e-08
11945                                                                  35   7e-04
15260                                                                  37   0.063
19079                                                                  37   0.078
19361                                                                  35   0.25 
05468                                                                  34   0.35 
34597                                                                  33   0.90 
08428                                                                  32   2.6  
08348                                                                  30   6.7  
09025                                                                  30   8.5  
>17558
          Length = 671

 Score = 94.0 bits (232), Expect = 4e-19,   Method: Compositional matrix adjust.
 Identities = 58/206 (28%), Positives = 108/206 (52%), Gaps = 2/206 (0%)
 Frame = +3

Query: 1249 NPPTRRNWESNYFGMPLQDLVTAE-KPIPLFVEKCVEFIEDTGLCTEGLYRVSGNKTDQD 1307
             PP     +   FG  L++ + A  + IPL ++ C+  I   GL  +G++RVSG + + +
Sbjct: 30   TPPV---GQPKLFGGSLEEYIEATGEEIPLIIKGCIRVINLYGLHHQGVFRVSGAQVEIN 200

Query: 1308 NIQKQFDQDHNINLASMEVT-VNAVAGALKAFFADLPDPLIPYSLHPELLEAAKIPDKTE 1366
            + +  F+   +  +  ++ + +N++AG LK +F +L +PL P  L   L+E  +  D   
Sbjct: 201  HFKNVFESGDDALVDVVDASDMNSIAGVLKLYFRELREPLFPLHLFDALVECTRENDVHR 380

Query: 1367 RFHALKEIVKKFHPVNYDVFRYVITHLNRVSQQNKINLMTADNLSICFWPTLMRPDFENR 1426
            R   +K+++       + V RY+   LN +S+ +  N+M   NL+ICF PTL+ P   +R
Sbjct: 381  RLERIKDLLATLPRSVFVVMRYLFAFLNHLSEYSDENMMDPYNLAICFGPTLL-PIPPDR 557

Query: 1427 EFLSTTKIHQSVVETFIQQCQFFFYN 1452
            + +    + Q +++T I   +  F N
Sbjct: 558  DQVVLPGLRQRIIKTIIVHQEEIFPN 635
>17428
          Length = 623

 Score = 87.0 bits (214), Expect = 5e-17,   Method: Compositional matrix adjust.
 Identities = 45/157 (28%), Positives = 86/157 (54%)
 Frame = +1

Query: 1294 EGLYRVSGNKTDQDNIQKQFDQDHNINLASMEVTVNAVAGALKAFFADLPDPLIPYSLHP 1353
            EGL+R S      + ++  FD    +++       N VAG +K +  +LP+P++ + L+P
Sbjct: 1    EGLFRFSRISFKDEKLKACFDA-RLVDMEEFSNDPNTVAGVMKQYLRELPEPMLTFDLYP 177

Query: 1354 ELLEAAKIPDKTERFHALKEIVKKFHPVNYDVFRYVITHLNRVSQQNKINLMTADNLSIC 1413
            + + AA++    ++  +L  +V +  P N++ FRY+I  L  +++++ +N MT  NL+I 
Sbjct: 178  DFMRAAQL-GHDQKCQSLYTLVNRLPPSNFNNFRYLIKFLALLAEKSHVNKMTPSNLAIV 354

Query: 1414 FWPTLMRPDFENREFLSTTKIHQSVVETFIQQCQFFF 1450
              P L+    EN   + T     S++ETF+   ++FF
Sbjct: 355  MGPNLLWARGENTPNMMTASTVSSIIETFVLHAEYFF 465
>12558
          Length = 720

 Score = 72.0 bits (175), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 45/165 (27%), Positives = 80/165 (48%), Gaps = 7/165 (4%)
 Frame = -1

Query: 1293 TEGLYRVSGNKTDQDNIQKQFDQDHNINLA---SMEVTVNAVAGALKAFFADLPDPLIPY 1349
             +GLYR+SG  ++   ++  FD+D    L+        +++++  LK +F +LP+PL+ Y
Sbjct: 717  VDGLYRLSGVTSNIQKLRVAFDEDQAPELSDNVQYLQDIHSISSLLKMYFRELPNPLLTY 538

Query: 1350 SLHPELLEAAKIPDKTERFHALKEIVKKFHPVNYDVFRYVITHLNRVSQQNKINLMTADN 1409
             L+ +  +A K  D+  R   + ++V++  P +Y    Y++ HL  V+       M + N
Sbjct: 537  QLYTQFADAVK--DEDNRLLRIHDVVQQLPPPHYRTLEYLVRHLACVASYGLQTGMHSKN 364

Query: 1410 LSICFWPTLMRP-DFE---NREFLSTTKIHQSVVETFIQQCQFFF 1450
            L+I + P L+R  + E       L    I   V E  I  C   F
Sbjct: 363  LAIVWAPNLLRSKELEQGGGAAALRGVGIQAVVTECLICYCDLIF 229
>30765
          Length = 635

 Score = 69.3 bits (168), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 41/116 (35%), Positives = 65/116 (56%), Gaps = 1/116 (0%)
 Frame = +2

Query: 1261 FGMPLQDLVTAEK-PIPLFVEKCVEFIEDTGLCTEGLYRVSGNKTDQDNIQKQFDQDHNI 1319
            FG  LQ     +K P+P FV +C+  +E  GL  +GLYRVSGN  +   ++   D+D + 
Sbjct: 278  FGSTLQAQCDKDKAPVPNFVLECIAAVEKKGLDQDGLYRVSGNLAEIQRLRYVVDKDDDH 457

Query: 1320 NLASMEVTVNAVAGALKAFFADLPDPLIPYSLHPELLEAAKIPDKTERFHALKEIV 1375
            NL   +  ++ + GALK FF +L +PL P+    + + A+K   K E+  A K+ +
Sbjct: 458  NLTEDQWDIHTLTGALKLFFRELKEPLFPWKCIDKFINASKKEFKKEKMKAFKDAI 625
>20879
          Length = 1019

 Score = 62.8 bits (151), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 32/97 (32%), Positives = 56/97 (57%), Gaps = 1/97 (1%)
 Frame = -2

Query: 1265 LQDLVTAEKP-IPLFVEKCVEFIEDTGLCTEGLYRVSGNKTDQDNIQKQFDQDHNINLAS 1323
            L D    ++P IP  V  C   IE  GL   G+YRV G+  D  +++++F +  + NL++
Sbjct: 598  LADFAPTQRPMIPRLVVNCANEIERRGLSEVGIYRVPGSDRDSKDLKEKFLKGKSPNLSN 419

Query: 1324 MEVTVNAVAGALKAFFADLPDPLIPYSLHPELLEAAK 1360
            + + ++ V G LK F  +L +PL+ ++L P+L E  +
Sbjct: 418  I-IDIHTVCGCLKDFLRNLKEPLVTFALWPQLCEVQR 311
>02134
          Length = 1512

 Score = 57.0 bits (136), Expect = 5e-08,   Method: Compositional matrix adjust.
 Identities = 58/203 (28%), Positives = 92/203 (45%), Gaps = 2/203 (0%)
 Frame = -1

Query: 346 FNTLLPDLEEIEHLNWLEALKLMEKRADFQLCFVVLEKTPWDETDHIDKINDRRIPFDLL 405
           FN L+ DL       W E  K +  R D +          WD TD +DK +         
Sbjct: 753 FNALMADLVRNCESTWRETRKQL--RKDHR----------WDLTDQLDKED--------- 637

Query: 406 STLEAEKVYQNHVQHLISEKRRIEMKEKFKKTLEKIQFISPGQPWEEVMCFVMEDEAFKY 465
                EK+++ H+++L   KR  +M   F K L++ + IS    W+EV   + ED  +  
Sbjct: 636 ----KEKLFEVHIENLT--KRNKDM---FHKLLDETE-ISLTSTWKEVKKIIKEDPRYSK 487

Query: 466 ITEADSK--EVYGRHQREIVEKAKEEFQEMLFEHSELFYDLDLNATPSSDKMSEIHTVLS 523
            + +D K  + Y  +  E    AK EF+E+L E   + +   +    +   + EIH +L 
Sbjct: 486 FSSSDRKREKEYSEYMSEKFVTAKTEFRELLKETKAITFRSRMMMEENPAHLDEIHKILE 307

Query: 524 EEPRYKALQKLAPDRESLLLKHI 546
            + RY  L+ +  DRE +LL HI
Sbjct: 306 NDKRYLTLECVPEDREKILLLHI 238
>11945
          Length = 1161

 Score = 34.7 bits (78), Expect(2) = 7e-04,   Method: Compositional matrix adjust.
 Identities = 29/116 (25%), Positives = 50/116 (43%), Gaps = 1/116 (0%)
 Frame = -1

Query: 1298 RVSGNKTDQDNIQKQFDQDHNINLASM-EVTVNAVAGALKAFFADLPDPLIPYSLHPELL 1356
            RV G+ T    ++ + ++    N  +  EV  N  A  LK F  +LP PL+ Y       
Sbjct: 417  RVPGSVTRVKQLRHELEEKFYQNTFNWGEVMPNDCAALLKQFLRELPTPLLTYDYLEAFP 238

Query: 1357 EAAKIPDKTERFHALKEIVKKFHPVNYDVFRYVITHLNRVSQQNKINLMTADNLSI 1412
            +   IP   E+  AL  +V      + DV + ++  L  +   +  N M  +N+ +
Sbjct: 237  QVENIPKTLEQLKALNLLVLLLPTEHRDVLKVLLRFLRNIVSHSDTNKMGLNNICM 70

 Score = 27.7 bits (60), Expect(2) = 7e-04,   Method: Composition-based stats.
 Identities = 14/42 (33%), Positives = 24/42 (57%), Gaps = 6/42 (14%)
 Frame = -3

Query: 1261 FGMPLQDLVTAEKP------IPLFVEKCVEFIEDTGLCTEGL 1296
            FG+PL  L+  ++       +PLF +K V+ +E  G+  EG+
Sbjct: 547  FGVPLPVLLEHDQKHXPGVRVPLFFQKLVDHLEREGVGMEGI 422
>15260
          Length = 455

 Score = 37.0 bits (84), Expect = 0.063,   Method: Compositional matrix adjust.
 Identities = 21/61 (34%), Positives = 33/61 (54%)
 Frame = +3

Query: 486 AKEEFQEMLFEHSELFYDLDLNATPSSDKMSEIHTVLSEEPRYKALQKLAPDRESLLLKH 545
           AK EF+E+L E   + +   +    +   + EIH +L  + RY  L+ +  DRE +LL H
Sbjct: 27  AKTEFRELLKETKAITFRSRMMMEENPAHLDEIHKILENDKRYLTLECVPEDREKILLLH 206

Query: 546 I 546
           I
Sbjct: 207 I 209
>19079
          Length = 436

 Score = 36.6 bits (83), Expect = 0.078,   Method: Composition-based stats.
 Identities = 23/90 (25%), Positives = 45/90 (50%), Gaps = 4/90 (4%)
 Frame = -1

Query: 1303 KTDQDNIQKQFDQDHNINLASMEVT----VNAVAGALKAFFADLPDPLIPYSLHPELLEA 1358
            + D +N +  F+   +   A ++VT    +N+VAG LK +F +L +PL P  L   L+E 
Sbjct: 379  QVDINNFKAVFESGED---ALVDVTDASEMNSVAGVLKLYFRELREPLFPLHLFDALVEC 209

Query: 1359 AKIPDKTERFHALKEIVKKFHPVNYDVFRY 1388
             +      R  ++++++       + V R+
Sbjct: 208  TREISVQRRLDSIRDLLASLPRAIFVVMRW 119
>19361
          Length = 685

 Score = 35.0 bits (79), Expect = 0.25,   Method: Compositional matrix adjust.
 Identities = 18/45 (40%), Positives = 28/45 (62%), Gaps = 1/45 (2%)
 Frame = -1

Query: 1261 FGMPLQDLVTAEKPI-PLFVEKCVEFIEDTGLCTEGLYRVSGNKT 1304
            +G+ L  +  A K I P+ VE C++ IE  G+  EGLYR++ + T
Sbjct: 136  YGVDLTTVTKANKQILPIVVEXCIKEIEKRGVEPEGLYRLAXSTT 2
>05468
          Length = 1558

 Score = 34.3 bits (77), Expect = 0.35,   Method: Compositional matrix adjust.
 Identities = 32/101 (31%), Positives = 52/101 (51%), Gaps = 7/101 (6%)
 Frame = -3

Query: 158  GFLLCIDVSQGCNRKFDDQLKFVNNL--FVQLS-KSKKPVIIAATKCDECVDHYLR---E 211
            G  +  DV++     FD   K+ N+L   VQL+  S  P ++ A KCD+  +  +    +
Sbjct: 1313 GAFVVFDVTRAST--FDAVTKWKNDLDSKVQLADGSPVPCVLLANKCDQAKEGLVNNTSQ 1140

Query: 212  VQAFASNKKNLLVVETSARFNVNIETCFTALV-QMLDKTRG 251
            +  F S K  +   ETSA+ N+NI+     LV ++L+K R 
Sbjct: 1139 MDEFCSEKGFIGWYETSAKENINIDEAARFLVTRILEKDRA 1017
>34597
          Length = 773

 Score = 33.1 bits (74), Expect = 0.90,   Method: Composition-based stats.
 Identities = 23/84 (27%), Positives = 48/84 (57%), Gaps = 2/84 (2%)
 Frame = -2

Query: 171 RKFDDQLKFVNNLFVQLSKSKKPVIIAATKCDECVDHYLREVQAFA-SNKKNLLVVETSA 229
           + F++ +K++ N+    ++  + +I+   KCD      + + +  A + + ++  +ETSA
Sbjct: 712 KSFENIVKWLRNIDEHANEDVEKMILG-NKCDMTDKRVVSKERGEAIAREHSIRFMETSA 536

Query: 230 RFNVNIETCFTALVQ-MLDKTRGK 252
           + N+NIE  F  L + +LDKT G+
Sbjct: 535 KSNINIERAFCELAEAILDKTAGR 464
>08428
          Length = 1109

 Score = 31.6 bits (70), Expect = 2.6,   Method: Compositional matrix adjust.
 Identities = 25/75 (33%), Positives = 35/75 (46%), Gaps = 5/75 (6%)
 Frame = -3

Query: 177 LKFVNNLFVQLSKSKKPVIIAATKCDECVDHYLREV-----QAFASNKKNLLVVETSARF 231
            K V +   +L     P I+ A   ++C    LREV     Q +AS+   +   ETSA  
Sbjct: 807 FKSVKSWIQELRSFGPPNIVLAIAGNKCDLEELREVVEKDAQEYASSISAIFG-ETSAMT 631

Query: 232 NVNIETCFTALVQML 246
            VN+E  FT L + L
Sbjct: 630 AVNVEEMFTELARQL 586
>08348
          Length = 1550

 Score = 30.0 bits (66), Expect = 6.7,   Method: Composition-based stats.
 Identities = 15/58 (25%), Positives = 33/58 (56%), Gaps = 2/58 (3%)
 Frame = -1

Query: 62   FGGRVVNNDHFLYWGDITQNGEDGVECKIHVIEQTE--FIDDQTFLPHRSTNLQPYIK 117
            + G V+   H  + G + QNGE  + C++H+++ +    + +++    +S+NL  Y+K
Sbjct: 1364 YPGDVIYTQHGRHTGQVGQNGEHVIGCEVHLVQLSSGNIVHEES--QGQSSNLVCYVK 1197
>09025
          Length = 1044

 Score = 29.6 bits (65), Expect = 8.5,   Method: Composition-based stats.
 Identities = 15/56 (26%), Positives = 32/56 (57%), Gaps = 2/56 (3%)
 Frame = -3

Query: 64  GRVVNNDHFLYWGDITQNGEDGVECKIHVIEQTE--FIDDQTFLPHRSTNLQPYIK 117
           G V+   H  + G + QNGE  + C++H+++ +    + +++    +S+NL  Y+K
Sbjct: 205 GDVIYTQHGRHTGQVGQNGEHVIGCEVHLVQLSSGNIVHEES--QGQSSNLVCYVK 44
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|145699097|ref|NP_067383.3| usherin [Mus musculus]
         (5193 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

08188                                                                  96   5e-19
19544                                                                  51   1e-05
34444                                                                  50   2e-05
17679                                                                  50   2e-05
17229                                                                  49   6e-05
32228                                                                  49   7e-05
29742                                                                  48   1e-04
26039                                                                  45   6e-04
27883                                                                  44   0.002
23938                                                                  39   0.041
18367                                                                  39   0.055
25554                                                                  37   0.17 
26607                                                                  36   0.49 
35879                                                                  35   0.64 
11667                                                                  35   1.2  
31203                                                                  33   4.2  
11044                                                                  32   7.7  
>08188
          Length = 786

 Score = 95.5 bits (236), Expect = 5e-19,   Method: Compositional matrix adjust.
 Identities = 64/153 (41%), Positives = 81/153 (52%), Gaps = 2/153 (1%)
 Frame = -3

Query: 638 CDCNRAGTRNGSLHCDPIGGQCDCKRRVSGRQCLQCQDGFYDLQALDPDGCRPCNCNPSG 697
           CDC+  G+   SL CD  G +C CK  V GR+C QC  G Y      PDGC+PCNC+  G
Sbjct: 427 CDCDPMGSV--SLECDTSGCKCPCKTNVVGRRCDQCAPGTY---GFGPDGCQPCNCHEIG 263

Query: 698 TVDGDITCHQNSGQCSCKANVIGLRCNRCNFGF-KFLQSFNGDGCEPCQCNLHGSVNQLC 756
             D    C++ SGQC+C  NV    C++C  GF  F Q      C PCQCN +      C
Sbjct: 262 ARDN--FCNEQSGQCTCIQNVGQRTCDQCRDGFWGFPQ------CRPCQCNGNADT---C 116

Query: 757 DPLSGQCA-CKKEAKGLKCDSCRENFYGLPWSA 788
           DPL+G C  C+    G  C  C +N+YG P + 
Sbjct: 115 DPLTGACQDCRDHTDGDFCKRCEDNYYGDPRAG 17

 Score = 94.7 bits (234), Expect = 8e-19,   Method: Compositional matrix adjust.
 Identities = 66/177 (37%), Positives = 94/177 (53%), Gaps = 1/177 (0%)
 Frame = -3

Query: 824 SQCKAGYFNLYQNDSHLCLTCNCEKMGTVNGSLRCDKSTGQCPCKLGVTGLRCHQCKPHR 883
            +CK   F++    ++  LTC+C+ MG+V  SL CD S  +CPCK  V G RC QC P  
Sbjct: 487 EECKRHTFSISSVLNNGALTCDCDPMGSV--SLECDTSGCKCPCKTNVVGRRCDQCAPGT 314

Query: 884 FNLTMDNPQGCQACDCDSLGTLPGSMCDPISGQCLCLPHRQGRRCEQCQPGFYSSPSNAT 943
           +      P GCQ C+C  +G    + C+  SGQC C+ +   R C+QC+ GF+  P    
Sbjct: 313 YGF---GPDGCQPCNCHEIGAR-DNFCNEQSGQCTCIQNVGQRTCDQCRDGFWGFPQ--- 155

Query: 944 GCLPCLCHTAGAVSHICNSVTGQC-SCHDPSTTGRSCHQCQESYFRFDPLTGRCRPC 999
            C PC C+     +  C+ +TG C  C D  T G  C +C+++Y+  DP  G   PC
Sbjct: 154 -CRPCQCN---GNADTCDPLTGACQDCRD-HTDGDFCKRCEDNYYG-DPRAGVRIPC 2

 Score = 83.6 bits (205), Expect = 2e-15,   Method: Compositional matrix adjust.
 Identities = 52/161 (32%), Positives = 82/161 (50%), Gaps = 1/161 (0%)
 Frame = -3

Query: 672 QCQDGFYDLQALDPDGCRPCNCNPSGTVDGDITCHQNSGQCSCKANVIGLRCNRCNFGFK 731
           +C+   + + ++  +G   C+C+P G+V   + C  +  +C CK NV+G RC++C  G  
Sbjct: 484 ECKRHTFSISSVLNNGALTCDCDPMGSVS--LECDTSGCKCPCKTNVVGRRCDQCAPG-- 317

Query: 732 FLQSFNGDGCEPCQCNLHGSVNQLCDPLSGQCACKKEAKGLKCDSCRENFYGLPWSACEV 791
               F  DGC+PC C+  G+ +  C+  SGQC C +      CD CR+ F+G P   C  
Sbjct: 316 -TYGFGPDGCQPCNCHEIGARDNFCNEQSGQCTCIQNVGQRTCDQCRDGFWGFP--QCRP 146

Query: 792 CDCSKAGSQPGTVCDTETGQCV-CKPNVGGRQCSQCKAGYF 831
           C C+         CD  TG C  C+ +  G  C +C+  Y+
Sbjct: 145 CQCNGNAD----TCDPLTGACQDCRDHTDGDFCKRCEDNYY 35

 Score = 78.6 bits (192), Expect = 7e-14,   Method: Compositional matrix adjust.
 Identities = 51/144 (35%), Positives = 71/144 (49%), Gaps = 15/144 (10%)
 Frame = -3

Query: 877  HQCKPHRFNLTMDNPQGCQACDCDSLGTLPGSMCDPISGQCLCLPHRQGRRCEQCQPGFY 936
             +CK H F+++     G   CDCD +G++    CD    +C C  +  GRRC+QC PG Y
Sbjct: 487  EECKRHTFSISSVLNNGALTCDCDPMGSV-SLECDTSGCKCPCKTNVVGRRCDQCAPGTY 311

Query: 937  SSPSNATGCLPCLCHTAGAVSHICNSVTGQCSCHDPSTTGRSCHQCQESYFRF------- 989
                   GC PC CH  GA  + CN  +GQC+C   +   R+C QC++ ++ F       
Sbjct: 310  GF--GPDGCQPCNCHEIGARDNFCNEQSGQCTCIQ-NVGQRTCDQCRDGFWGFPQCRPCQ 140

Query: 990  --------DPLTGRCRPCHCHVAG 1005
                    DPLTG C+ C  H  G
Sbjct: 139  CNGNADTCDPLTGACQDCRDHTDG 68

 Score = 70.1 bits (170), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 48/143 (33%), Positives = 69/143 (48%), Gaps = 2/143 (1%)
 Frame = -3

Query: 744 CQCNLHGSVNQLCDPLSGQCACKKEAKGLKCDSCRENFYGLPWSACEVCDCSKAGSQPGT 803
           C C+  GSV+  CD    +C CK    G +CD C    YG     C+ C+C + G++   
Sbjct: 427 CDCDPMGSVSLECDTSGCKCPCKTNVVGRRCDQCAPGTYGFGPDGCQPCNCHEIGAR-DN 251

Query: 804 VCDTETGQCVCKPNVGGRQCSQCKAGYFNLYQNDSHLCLTCNCEKMGTVNGSLR-CDKST 862
            C+ ++GQC C  NVG R C QC+ G++   Q     C  C C      NG+   CD  T
Sbjct: 250 FCNEQSGQCTCIQNVGQRTCDQCRDGFWGFPQ-----CRPCQC------NGNADTCDPLT 104

Query: 863 GQC-PCKLGVTGLRCHQCKPHRF 884
           G C  C+    G  C +C+ + +
Sbjct: 103 GACQDCRDHTDGDFCKRCEDNYY 35

 Score = 57.0 bits (136), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 43/123 (34%), Positives = 57/123 (46%), Gaps = 1/123 (0%)
 Frame = -3

Query: 605 CQHHTTGRHCESCQDYFYRPVGADPAAPDACKLCDCNRAGTRNGSLHCDPIGGQCDCKRR 664
           C+ +  GR C+ C    Y         PD C+ C+C+  G R+    C+   GQC C + 
Sbjct: 364 CKTNVVGRRCDQCAPGTYG------FGPDGCQPCNCHEIGARDN--FCNEQSGQCTCIQN 209

Query: 665 VSGRQCLQCQDGFYDLQALDPDGCRPCNCNPSGTVDGDITCHQNSGQC-SCKANVIGLRC 723
           V  R C QC+DGF+         CRPC CN  G  D   TC   +G C  C+ +  G  C
Sbjct: 208 VGQRTCDQCRDGFWGFPQ-----CRPCQCN--GNAD---TCDPLTGACQDCRDHTDGDFC 59

Query: 724 NRC 726
            RC
Sbjct: 58  KRC 50

 Score = 55.1 bits (131), Expect = 8e-07,   Method: Compositional matrix adjust.
 Identities = 34/93 (36%), Positives = 46/93 (49%)
 Frame = -3

Query: 943  TGCLPCLCHTAGAVSHICNSVTGQCSCHDPSTTGRSCHQCQESYFRFDPLTGRCRPCHCH 1002
             G L C C   G+VS  C++   +C C   +  GR C QC    + F P    C+PC+CH
Sbjct: 442  NGALTCDCDPMGSVSLECDTSGCKCPCK-TNVVGRRCDQCAPGTYGFGP--DGCQPCNCH 272

Query: 1003 VAGASNGTCDAVTGQCFCKEFVTGSKCDTCVPG 1035
              GA +  C+  +GQC C + V    CD C  G
Sbjct: 271  EIGARDNFCNEQSGQCTCIQNVGQRTCDQCRDG 173

 Score = 42.4 bits (98), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 24/63 (38%), Positives = 32/63 (50%)
 Frame = -3

Query: 569 CKPCQCHGHASSCHYDASVDPFPLEHNRGGGGVCDDCQHHTTGRHCESCQDYFYRPVGAD 628
           C+PCQC+G+A +C      DP          G C DC+ HT G  C+ C+D +Y     D
Sbjct: 154 CRPCQCNGNADTC------DPLT--------GACQDCRDHTDGDFCKRCEDNYY----GD 29

Query: 629 PAA 631
           P A
Sbjct: 28  PRA 20

 Score = 36.6 bits (83), Expect = 0.29,   Method: Compositional matrix adjust.
 Identities = 54/222 (24%), Positives = 84/222 (37%), Gaps = 10/222 (4%)
 Frame = -3

Query: 467 FYNSSVLQEFMRATQIRLHFHGQYYPAGHTV---DWRHQYYAVDEIIVSGR--CQCHGHA 521
            Y    L E+M    +R       YP+       + +   +++  ++ +G   C C    
Sbjct: 586 IYQGPGLPEYMLNEFLRFRCQQLQYPSIKQELPEECKRHTFSISSVLNNGALTCDCDPMG 407

Query: 522 ET---CDRTRRPYRCLCSPHSFTEGPQCDRCSP-LYNDKPFRSGDNVNAFNCKPCQCHGH 577
                CD +     C C   +   G +CD+C+P  Y   P           C+PC CH  
Sbjct: 406 SVSLECDTSG----CKCPCKTNVVGRRCDQCAPGTYGFGP---------DGCQPCNCHEI 266

Query: 578 ASSCHYDASVDPFPLEHNRGGGGVCDDCQHHTTGRHCESCQDYFYRPVGADPAAPDACKL 637
            +        D F  E +    G C  C  +   R C+ C+D F+         P  C+ 
Sbjct: 265 GAR-------DNFCNEQS----GQC-TCIQNVGQRTCDQCRDGFW-------GFP-QCRP 146

Query: 638 CDCNRAGTRNGSLHCDPIGGQC-DCKRRVSGRQCLQCQDGFY 678
           C CN       +  CDP+ G C DC+    G  C +C+D +Y
Sbjct: 145 CQCN-----GNADTCDPLTGACQDCRDHTDGDFCKRCEDNYY 35
>19544
          Length = 1421

 Score = 50.8 bits (120), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 54/168 (32%), Positives = 73/168 (43%), Gaps = 11/168 (6%)
 Frame = +2

Query: 4700 YEYQVWAVNSAGKA--ASNWTRCRTGPAPPEG---LQAPTFHTVSSTRAVVNISVPSRPN 4754
            YE QV AVN  G+   ++  T      AP EG   +QA    + SS +       P   N
Sbjct: 20   YEVQVLAVNGKGRGPPSTPATIYVGEAAPTEGPSNVQA-VNKSASSIQVTWVAPPPETQN 196

Query: 4755 GNISLFRV--FSNSSGTHVTLSEGTA-TQQTLHDLSPFTTYTIGVEACTCFNCCSRGPTA 4811
            G +S ++V  +  SS     L+  TA T   L  L  FT Y I V+    +N    GP +
Sbjct: 197  GGLSGYKVLYYKQSSSAEEELTRITAETHILLESLETFTVYFIAVQP---YNLAGEGPRS 367

Query: 4812 EL---RTHPAPPSGLSPPQVQTLGSRMASVHWTPPLLPNGVIHSYELQ 4856
             L   +T    PS     +   +  R   VH+ PP  PNG I  YE+Q
Sbjct: 368  ALVSAQTSEGVPSAPQSIRFTNITMRQLMVHFDPPTTPNGHILLYEMQ 511

 Score = 37.4 bits (85), Expect = 0.17,   Method: Compositional matrix adjust.
 Identities = 35/124 (28%), Positives = 52/124 (41%), Gaps = 15/124 (12%)
 Frame = +2

Query: 4451 SIEITWT--PPRNPHGLIRSY-------------ELRRDGAIVYVGLETRYHDFTLAPGV 4495
            SI++TW   PP   +G +  Y             EL R  A  ++ LE+    FT+    
Sbjct: 152  SIQVTWVAPPPETQNGGLSGYKVLYYKQSSSAEEELTRITAETHILLES-LETFTVYFIA 328

Query: 4496 EYSYSVTATNSRGSVLSPLVKGQTSPSAPSGLQPPKLHSGDALELLADWDPPVRTNGKII 4555
               Y++     R    S LV  QTS   PS  Q  +  +    +L+  +DPP   NG I+
Sbjct: 329  VQPYNLAGEGPR----SALVSAQTSEGVPSAPQSIRFTNITMRQLMVHFDPPTTPNGHIL 496

Query: 4556 NYTL 4559
             Y +
Sbjct: 497  LYEM 508

 Score = 35.0 bits (79), Expect = 0.83,   Method: Compositional matrix adjust.
 Identities = 36/140 (25%), Positives = 58/140 (41%), Gaps = 8/140 (5%)
 Frame = +2

Query: 4253 APPDGLSPPEISYVSMSPLQLLISWL--PPRHSNGVIQGYRL----QRDGVLPALN-FNA 4305
            AP +G  P  +  V+ S   + ++W+  PP   NG + GY++    Q       L    A
Sbjct: 101  APTEG--PSNVQAVNKSASSIQVTWVAPPPETQNGGLSGYKVLYYKQSSSAEEELTRITA 274

Query: 4306 STFSYMDSQLLPFSTYSYAILACT-GGGCCTSEPTNITTXXXXXXXXXXXXLWDISAHQM 4364
             T   ++S L  F+ Y  A+      G    S   +  T              +I+  Q+
Sbjct: 275  ETHILLES-LETFTVYFIAVQPYNLAGEGPRSALVSAQTSEGVPSAPQSIRFTNITMRQL 451

Query: 4365 NVSWSPPSIPNGKIVKYLLQ 4384
             V + PP+ PNG I+ Y +Q
Sbjct: 452  MVHFDPPTTPNGHILLYEMQ 511

 Score = 35.0 bits (79), Expect = 0.83,   Method: Compositional matrix adjust.
 Identities = 42/176 (23%), Positives = 71/176 (40%), Gaps = 12/176 (6%)
 Frame = +2

Query: 4030 TYHIGVVAVNSAGK--VSSPWTLIKTLESAPSGLMNFTVEQREKGRALLLQWSEP--VKT 4085
            TY + V+AVN  G+   S+P T I   E+AP+   +      +   ++ + W  P     
Sbjct: 17   TYEVQVLAVNGKGRGPPSTPAT-IYVGEAAPTEGPSNVQAVNKSASSIQVTWVAPPPETQ 193

Query: 4086 NGVIKAYNI--FNDGVLEYSGLGR-----QFLFRRLAPFTLYTLILEACTTAGCA-HSVP 4137
            NG +  Y +  +         L R       L   L  FT+Y + ++    AG    S  
Sbjct: 194  NGGLSGYKVLYYKQSSSAEEELTRITAETHILLESLETFTVYFIAVQPYNLAGEGPRSAL 373

Query: 4138 QPLWTEEAPPDTQMAPTIQSVGPTNVRLHWSQPASPNGKIIHYEVIRRRSEEEDWG 4193
                T E  P    +    ++    + +H+  P +PNG I+ YE+     +E  +G
Sbjct: 374  VSAQTSEGVPSAPQSIRFTNITMRQLMVHFDPPTTPNGHILLYEMQYFPKDESRYG 541
>34444
          Length = 403

 Score = 50.4 bits (119), Expect = 2e-05,   Method: Composition-based stats.
 Identities = 24/61 (39%), Positives = 29/61 (47%)
 Frame = +1

Query: 996  CRPCHCHVAGASNGTCDAVTGQCFCKEFVTGSKCDTCVPGASHLDVNNLLGCSKTPSQQP 1055
            C+ C CH  GA    C+  TGQC CK+ VTG  CD C  G      + +  C K P    
Sbjct: 52   CKACKCHPVGALGKMCNQTTGQCPCKDGVTGLTCDRCAKGYQQ-SKSPIAPCIKIPKPTS 228

Query: 1056 P 1056
            P
Sbjct: 229  P 231

 Score = 49.3 bits (116), Expect = 4e-05,   Method: Composition-based stats.
 Identities = 24/56 (42%), Positives = 31/56 (55%), Gaps = 3/56 (5%)
 Frame = +1

Query: 827 KAGYF---NLYQNDSHLCLTCNCEKMGTVNGSLRCDKSTGQCPCKLGVTGLRCHQC 879
           K GY+   N    D   C  C C  +G +     C+++TGQCPCK GVTGL C +C
Sbjct: 1   KEGYYRDGNKLITDRRACKACKCHPVGALGK--MCNQTTGQCPCKDGVTGLTCDRC 162

 Score = 48.5 bits (114), Expect = 6e-05,   Method: Composition-based stats.
 Identities = 20/48 (41%), Positives = 28/48 (58%)
 Frame = +1

Query: 684 DPDGCRPCNCNPSGTVDGDITCHQNSGQCSCKANVIGLRCNRCNFGFK 731
           D   C+ C C+P G +     C+Q +GQC CK  V GL C+RC  G++
Sbjct: 40  DRRACKACKCHPVGALGK--MCNQTTGQCPCKDGVTGLTCDRCAKGYQ 177

 Score = 47.4 bits (111), Expect = 1e-04,   Method: Composition-based stats.
 Identities = 19/47 (40%), Positives = 26/47 (55%)
 Frame = +1

Query: 940 SNATGCLPCLCHTAGAVSHICNSVTGQCSCHDPSTTGRSCHQCQESY 986
           ++   C  C CH  GA+  +CN  TGQC C D   TG +C +C + Y
Sbjct: 37  TDRRACKACKCHPVGALGKMCNQTTGQCPCKD-GVTGLTCDRCAKGY 174

 Score = 45.4 bits (106), Expect = 5e-04,   Method: Composition-based stats.
 Identities = 21/62 (33%), Positives = 32/62 (51%)
 Frame = +1

Query: 885 NLTMDNPQGCQACDCDSLGTLPGSMCDPISGQCLCLPHRQGRRCEQCQPGFYSSPSNATG 944
           N  + + + C+AC C  +G L G MC+  +GQC C     G  C++C  G+  S S    
Sbjct: 25  NKLITDRRACKACKCHPVGAL-GKMCNQTTGQCPCKDGVTGLTCDRCAKGYQQSKSPIAP 201

Query: 945 CL 946
           C+
Sbjct: 202 CI 207

 Score = 44.7 bits (104), Expect = 9e-04,   Method: Composition-based stats.
 Identities = 15/42 (35%), Positives = 26/42 (61%)
 Frame = +1

Query: 740 GCEPCQCNLHGSVNQLCDPLSGQCACKKEAKGLKCDSCRENF 781
            C+ C+C+  G++ ++C+  +GQC CK    GL CD C + +
Sbjct: 49  ACKACKCHPVGALGKMCNQTTGQCPCKDGVTGLTCDRCAKGY 174

 Score = 44.3 bits (103), Expect = 0.001,   Method: Composition-based stats.
 Identities = 19/43 (44%), Positives = 24/43 (55%)
 Frame = +1

Query: 788 ACEVCDCSKAGSQPGTVCDTETGQCVCKPNVGGRQCSQCKAGY 830
           AC+ C C   G+  G +C+  TGQC CK  V G  C +C  GY
Sbjct: 49  ACKACKCHPVGAL-GKMCNQTTGQCPCKDGVTGLTCDRCAKGY 174

 Score = 36.6 bits (83), Expect = 0.29,   Method: Composition-based stats.
 Identities = 18/44 (40%), Positives = 24/44 (54%)
 Frame = +1

Query: 634 ACKLCDCNRAGTRNGSLHCDPIGGQCDCKRRVSGRQCLQCQDGF 677
           ACK C C+  G   G + C+   GQC CK  V+G  C +C  G+
Sbjct: 49  ACKACKCHPVGAL-GKM-CNQTTGQCPCKDGVTGLTCDRCAKGY 174
>17679
          Length = 509

 Score = 50.1 bits (118), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 31/93 (33%), Positives = 49/93 (52%), Gaps = 3/93 (3%)
 Frame = +3

Query: 3953 LEAP---PRGLPAPRVQATSAHSAMLNWTEPEAPNGLISQYHVIYQERPDAAAPGSSTVH 4009
            +EAP   PR +   R +A S+ + +++W+EPE PNG+I  Y V Y  +P+          
Sbjct: 117  VEAPGTAPRNV---RARAASSTTIVVSWSEPEIPNGIIQGYRVFYTRKPEEPV---FFWE 278

Query: 4010 AFTVTGTSRQAHLFGLEPFTTYHIGVVAVNSAG 4042
               V   +R   + GL+P  TY I ++A +S G
Sbjct: 279  QQEVKNDNRLTTISGLDPNQTYTISILAYSSIG 377

 Score = 40.0 bits (92), Expect = 0.025,   Method: Compositional matrix adjust.
 Identities = 26/101 (25%), Positives = 54/101 (53%)
 Frame = +3

Query: 1942 GTAPQSVPTPSRAQSINGSSVEVAWNEPAVVKGVLEKYVLKAYSEDSSQPRVPSASTELH 2001
            GTAP++V    RA++ + +++ V+W+EP +  G+++ Y +  Y+    +P       E+ 
Sbjct: 129  GTAPRNV----RARAASSTTIVVSWSEPEIPNGIIQGYRV-FYTRKPEEPVFFWEQQEVK 293

Query: 2002 DTSTHSGVLIGLHPFHSYTVTLTACSRAGCTESSQALSIST 2042
            + +  +  + GL P  +YT+++ A S  G    S  + + T
Sbjct: 294  NDNRLT-TISGLDPNQTYTISILAYSSIGPGPMSHPIQVLT 413

 Score = 38.5 bits (88), Expect = 0.077,   Method: Compositional matrix adjust.
 Identities = 27/94 (28%), Positives = 44/94 (46%), Gaps = 13/94 (13%)
 Frame = +3

Query: 2224 QALMEE--TIPEGVPAPRAHSYSPDSFNISWTEPEYPNGVITTYELYL-----------D 2270
            Q L+E   T P  V   RA + S  +  +SW+EPE PNG+I  Y ++            +
Sbjct: 108  QVLVEAPGTAPRNV---RARAASSTTIVVSWSEPEIPNGIIQGYRVFYTRKPEEPVFFWE 278

Query: 2271 DTLIHNSSGLSCHAYGFDPGSLHTFQVQACTAKG 2304
               + N + L+  + G DP   +T  + A ++ G
Sbjct: 279  QQEVKNDNRLTTIS-GLDPNQTYTISILAYSSIG 377

 Score = 36.6 bits (83), Expect = 0.23,   Method: Compositional matrix adjust.
 Identities = 21/71 (29%), Positives = 35/71 (49%), Gaps = 1/71 (1%)
 Frame = +3

Query: 4838 VHWTPPLLPNGVIHSYELQLQRACPPDSAPRCPPSHTERKYWGPGHR-ASLAGLQPNTAY 4896
            V W+ P +PNG+I  Y +   R       P  P    E++     +R  +++GL PN  Y
Sbjct: 183  VSWSEPEIPNGIIQGYRVFYTR------KPEEPVFFWEQQEVKNDNRLTTISGLDPNQTY 344

Query: 4897 GVQVVAYNEAG 4907
             + ++AY+  G
Sbjct: 345  TISILAYSSIG 377

 Score = 34.7 bits (78), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 30/100 (30%), Positives = 43/100 (43%), Gaps = 5/100 (5%)
 Frame = +3

Query: 3847 SPGTYVRTLEAAPVGLMPPLLKALGSSCIEVKWMPPTRPNGIITSYVVH--RRPADTEEE 3904
            +PGT  R + A          +A  S+ I V W  P  PNGII  Y V   R+P     E
Sbjct: 123  APGTAPRNVRA----------RAASSTTIVVSWSEPEIPNGIIQGYRVFYTRKP-----E 257

Query: 3905 SLLFVWSEGALEFTDDTGT---LRPFTLYEYRVRAWNSQG 3941
              +F W +  ++  +   T   L P   Y   + A++S G
Sbjct: 258  EPVFFWEQQEVKNDNRLTTISGLDPNQTYTISILAYSSIG 377

 Score = 33.5 bits (75), Expect = 2.0,   Method: Compositional matrix adjust.
 Identities = 19/46 (41%), Positives = 23/46 (50%)
 Frame = +3

Query: 1058 RGWVQSSSTINVSWSPPECPNAHWLTYTLFRNGSEIYTTEDEHPYY 1103
            R    SS+TI VSWS PE PN     Y +F      YT + E P +
Sbjct: 150  RARAASSTTIVVSWSEPEIPNGIIQGYRVF------YTRKPEEPVF 269

 Score = 33.5 bits (75), Expect = 2.4,   Method: Compositional matrix adjust.
 Identities = 26/89 (29%), Positives = 37/89 (41%)
 Frame = +3

Query: 1252 SPTELRIEWSPPVDSNGIIISYELYMRRWLSTEESLVFESHGLVSSHSALQSVNPSKNLL 1311
            S T + + WS P   NGII  Y ++  R    EE + F     V + + L          
Sbjct: 165  SSTTIVVSWSEPEIPNGIIQGYRVFYTR--KPEEPVFFWEQQEVKNDNRL---------- 308

Query: 1312 QQPQASTFISGLEPHTEYAFRVLAVNMAG 1340
                  T ISGL+P+  Y   +LA +  G
Sbjct: 309  ------TTISGLDPNQTYTISILAYSSIG 377

 Score = 33.1 bits (74), Expect = 3.0,   Method: Compositional matrix adjust.
 Identities = 27/93 (29%), Positives = 42/93 (45%), Gaps = 7/93 (7%)
 Frame = +3

Query: 4247 VVRTLQAPPDGLSPPEISYVSMSPLQLLISWLPPRHSNGVIQGYRL--QRDGVLPALNFN 4304
            +V+ L   P G +P  +   + S   +++SW  P   NG+IQGYR+   R    P   + 
Sbjct: 102  IVQVLVEAP-GTAPRNVRARAASSTTIVVSWSEPEIPNGIIQGYRVFYTRKPEEPVFFWE 278

Query: 4305 ASTFSYMD-----SQLLPFSTYSYAILACTGGG 4332
                   +     S L P  TY+ +ILA +  G
Sbjct: 279  QQEVKNDNRLTTISGLDPNQTYTISILAYSSIG 377

 Score = 32.0 bits (71), Expect = 5.8,   Method: Compositional matrix adjust.
 Identities = 31/117 (26%), Positives = 46/117 (39%), Gaps = 2/117 (1%)
 Frame = +3

Query: 4125 EACTTAGCAHSVPQPLWTEEAPPDTQMAPTIQSVGPTNVRLHWSQPASPNGKIIHYEVIR 4184
            EA +  G    + Q L   EAP         ++   T + + WS+P  PNG I  Y V  
Sbjct: 69   EASSDLGNIERIVQVLV--EAPGTAPRNVRARAASSTTIVVSWSEPEIPNGIIQGYRVFY 242

Query: 4185 RRSEEEDWGNTTWQADGNTVF--TEYNTQGNAWVYNDTGLQPWRQYAYRICAWNSAG 4239
             R  EE             VF   +   + +  +   +GL P + Y   I A++S G
Sbjct: 243  TRKPEE------------PVFFWEQQEVKNDNRLTTISGLDPNQTYTISILAYSSIG 377
>17229
          Length = 487

 Score = 48.5 bits (114), Expect = 6e-05,   Method: Composition-based stats.
 Identities = 41/136 (30%), Positives = 64/136 (47%), Gaps = 5/136 (3%)
 Frame = +1

Query: 1912 LQPFTEYLYRVTA-SHEGGAVSSDWSRGRTLGTAPQSVPTPSRAQSINGSSVEVAWNEPA 1970
            L P T Y  +V+A +  G    +   + +TL   P   P   RA++IN + + V W+EP 
Sbjct: 73   LTPDTIYYIQVSAKTVHGEGPRTPTIQTKTLPFLPGE-PRKLRAETINSTGIFVEWDEPK 249

Query: 1971 VVKGVLEKYVLKAYSEDSSQPRVPSASTE-LHDTST---HSGVLIGLHPFHSYTVTLTAC 2026
              +G +  Y +     + S+   PS  TE +HDT +      V+IGL     Y V +   
Sbjct: 250  DSRGKIRGYYVYYVKVNGSRDEPPSGLTEQVHDTVSGRVKEAVIIGLDADSRYRVQVAGY 429

Query: 2027 SRAGCTESSQALSIST 2042
            +R G    S++L I T
Sbjct: 430  TRKGDGRRSKSLVIDT 477

 Score = 39.3 bits (90), Expect = 0.037,   Method: Composition-based stats.
 Identities = 38/129 (29%), Positives = 58/129 (44%), Gaps = 10/129 (7%)
 Frame = +1

Query: 3924 LRPFTLYEYRVRAWNSQGAVDSPWS-TIQTLEAP-----PRGLPAPRVQATSAHSAMLNW 3977
            L P T+Y  +V A    G  + P + TIQT   P     PR L A  + +T      + W
Sbjct: 73   LTPDTIYYIQVSAKTVHG--EGPRTPTIQTKTLPFLPGEPRKLRAETINSTGI---FVEW 237

Query: 3978 TEPEAPNGLISQYHVIYQE----RPDAAAPGSSTVHAFTVTGTSRQAHLFGLEPFTTYHI 4033
             EP+   G I  Y+V Y +    R +  +  +  VH  TV+G  ++A + GL+  + Y +
Sbjct: 238  DEPKDSRGKIRGYYVYYVKVNGSRDEPPSGLTEQVHD-TVSGRVKEAVIIGLDADSRYRV 414

Query: 4034 GVVAVNSAG 4042
             V      G
Sbjct: 415  QVAGYTRKG 441

 Score = 34.7 bits (78), Expect = 1.1,   Method: Composition-based stats.
 Identities = 23/75 (30%), Positives = 38/75 (50%), Gaps = 2/75 (2%)
 Frame = +1

Query: 3457 DLKPSTVYEYRISAWNSYGRG-FSQSVRASTREDVPEGVKAPRWARTGK-HEDVIFLQWE 3514
            DL P T+Y  ++SA   +G G  + +++  T   +P     PR  R    +   IF++W+
Sbjct: 70   DLTPDTIYYIQVSAKTVHGEGPRTPTIQTKTLPFLP---GEPRKLRAETINSTGIFVEWD 240

Query: 3515 EPMQSNGPIIHYILF 3529
            EP  S G I  Y ++
Sbjct: 241  EPKDSRGKIRGYYVY 285

 Score = 32.3 bits (72), Expect = 4.7,   Method: Composition-based stats.
 Identities = 35/146 (23%), Positives = 55/146 (37%), Gaps = 17/146 (11%)
 Frame = +1

Query: 2477 FPIPSASLSYEVTGLQPFTVYEFRLVATNGFGTAYSAWTPLMTTEDKPGPIDAPILI--- 2533
            F I     +Y +  L P T+Y  ++ A    G      TP + T+  P     P  +   
Sbjct: 31   FSIRPPVNNYRLHDLTPDTIYYIQVSAKTVHGEG--PRTPTIQTKTLPFLPGEPRKLRAE 204

Query: 2534 NVKARMLSVIWRQPAKCNGAITHYNIY--------------LHGRLYLTVSGRVTNYTVV 2579
             + +  + V W +P    G I  Y +Y              L  +++ TVSGRV    ++
Sbjct: 205  TINSTGIFVEWDEPKDSRGKIRGYYVYYVKVNGSRDEPPSGLTEQVHDTVSGRVKEAVII 384

Query: 2580 PLHPYKAYHFQVEACTSQGCSKSPSS 2605
             L     Y  QV   T +G  +   S
Sbjct: 385  GLDADSRYRVQVAGYTRKGDGRRSKS 462

 Score = 32.3 bits (72), Expect = 5.5,   Method: Composition-based stats.
 Identities = 20/77 (25%), Positives = 35/77 (45%), Gaps = 1/77 (1%)
 Frame = +1

Query: 4485 RYHDFTLAPGVEYSYSVTATNSRGS-VLSPLVKGQTSPSAPSGLQPPKLHSGDALELLAD 4543
            R HD T  P   Y   V+A    G    +P ++ +T P  P   +  +  + ++  +  +
Sbjct: 61   RLHDLT--PDTIYYIQVSAKTVHGEGPRTPTIQTKTLPFLPGEPRKLRAETINSTGIFVE 234

Query: 4544 WDPPVRTNGKIINYTLF 4560
            WD P  + GKI  Y ++
Sbjct: 235  WDEPKDSRGKIRGYYVY 285
>32228
          Length = 1295

 Score = 48.5 bits (114), Expect = 7e-05,   Method: Compositional matrix adjust.
 Identities = 44/177 (24%), Positives = 69/177 (38%), Gaps = 6/177 (3%)
 Frame = -3

Query: 1499 KKSSLPAATAAVTKGTRFVGHGYCRFPRTAHAD-----FIGIKASFRTRVPEG-LILLAL 1552
            +K+     +  +    +  G+GY  F  T+        + GI  SFRTR  EG L+ + L
Sbjct: 978  EKTGGKDCSQVIESSRQLSGNGYLTFSSTSQNTVHYPWYNGI--SFRTRXKEGTLMQIIL 805

Query: 1553 SPGDQEEYFTLQLKNGRPYFLYNSQGTLVEVTPTDDPSQGYRDGEWHEIIAVRHQAFGQI 1612
            + G    + T+QL  G   + +      ++  P  D       G WH I A  +     +
Sbjct: 804  NTG----HVTIQLVRGFVQYTFEDSTVTLDAVPVSD-------GHWHYIEARWNHGRLNL 658

Query: 1613 TLDGQYTXXXXXXXXXXXXXXYTGLFVGGVPQGHSVLQKRLEIIQRGFVGCLKDVFI 1669
             LD                     ++VGG  QG+       E I  GF GC+KD+ +
Sbjct: 657  LLDYGQIEKSITLTQSVSGSDIQRIYVGGYRQGN-------EPISDGFSGCVKDIRV 508
>29742
          Length = 351

 Score = 47.8 bits (112), Expect = 1e-04,   Method: Composition-based stats.
 Identities = 27/85 (31%), Positives = 38/85 (44%), Gaps = 2/85 (2%)
 Frame = +3

Query: 701 GDITCHQNSGQCSCKANVIGLRCNRCNFGFKFLQSFNGDGCEPCQC--NLHGSVNQLCDP 758
           G +TC Q      C+    G  C+ C +G+   Q F    C PC C  N + S   +CD 
Sbjct: 3   GFLTCDQ------CEVGYTGNICHMCAYGYYLHQKF----CVPCHCHNNHNRSRPFMCDM 152

Query: 759 LSGQCACKKEAKGLKCDSCRENFYG 783
           ++G C C     GL C+ C   + G
Sbjct: 153 VTGACHCTYNTSGLNCEICHMGYEG 227

 Score = 45.4 bits (106), Expect = 6e-04,   Method: Composition-based stats.
 Identities = 28/98 (28%), Positives = 40/98 (40%)
 Frame = +3

Query: 648 GSLHCDPIGGQCDCKRRVSGRQCLQCQDGFYDLQALDPDGCRPCNCNPSGTVDGDITCHQ 707
           G L CD       C+   +G  C  C  G+Y  Q      C PC+C+ +        C  
Sbjct: 3   GFLTCD------QCEVGYTGNICHMCAYGYYLHQKF----CVPCHCHNNHNRSRPFMCDM 152

Query: 708 NSGQCSCKANVIGLRCNRCNFGFKFLQSFNGDGCEPCQ 745
            +G C C  N  GL C  C+ G++   + +   C P Q
Sbjct: 153 VTGACHCTYNTSGLNCEICHMGYEG-DALHLKNCAPIQ 263

 Score = 45.1 bits (105), Expect = 7e-04,   Method: Composition-based stats.
 Identities = 27/81 (33%), Positives = 34/81 (41%), Gaps = 2/81 (2%)
 Frame = +3

Query: 975  TGRSCHQCQESYFRFDPLTGRCRPCHCHVAGASNG--TCDAVTGQCFCKEFVTGSKCDTC 1032
            TG  CH C   Y+        C PCHCH     +    CD VTG C C    +G  C+ C
Sbjct: 39   TGNICHMCAYGYYLHQKF---CVPCHCHNNHNRSRPFMCDMVTGACHCTYNTSGLNCEIC 209

Query: 1033 VPGASHLDVNNLLGCSKTPSQ 1053
              G    D  +L  C+   S+
Sbjct: 210  HMGYEG-DALHLKNCAPIQSK 269

 Score = 43.9 bits (102), Expect = 0.002,   Method: Composition-based stats.
 Identities = 27/89 (30%), Positives = 33/89 (37%)
 Frame = +3

Query: 602 CDDCQHHTTGRHCESCQDYFYRPVGADPAAPDACKLCDCNRAGTRNGSLHCDPIGGQCDC 661
           CD C+   TG  C  C   +Y            C  C C+    R+    CD + G C C
Sbjct: 15  CDQCEVGYTGNICHMCAYGYY-------LHQKFCVPCHCHNNHNRSRPFMCDMVTGACHC 173

Query: 662 KRRVSGRQCLQCQDGFYDLQALDPDGCRP 690
               SG  C  C  G Y+  AL    C P
Sbjct: 174 TYNTSGLNCEICHMG-YEGDALHLKNCAP 257

 Score = 42.4 bits (98), Expect = 0.005,   Method: Composition-based stats.
 Identities = 21/66 (31%), Positives = 28/66 (42%)
 Frame = +3

Query: 814 CKPNVGGRQCSQCKAGYFNLYQNDSHLCLTCNCEKMGTVNGSLRCDKSTGQCPCKLGVTG 873
           C+    G  C  C  GY+ L+Q     C+ C+C      +    CD  TG C C    +G
Sbjct: 24  CEVGYTGNICHMCAYGYY-LHQK---FCVPCHCHNNHNRSRPFMCDMVTGACHCTYNTSG 191

Query: 874 LRCHQC 879
           L C  C
Sbjct: 192 LNCEIC 209

 Score = 42.0 bits (97), Expect = 0.007,   Method: Composition-based stats.
 Identities = 28/95 (29%), Positives = 42/95 (44%), Gaps = 1/95 (1%)
 Frame = +3

Query: 854 GSLRCDKSTGQCPCKLGVTGLRCHQCKPHRFNLTMDNPQGCQACDC-DSLGTLPGSMCDP 912
           G L CD+      C++G TG  CH C  + + L   + + C  C C ++       MCD 
Sbjct: 3   GFLTCDQ------CEVGYTGNICHMCA-YGYYL---HQKFCVPCHCHNNHNRSRPFMCDM 152

Query: 913 ISGQCLCLPHRQGRRCEQCQPGFYSSPSNATGCLP 947
           ++G C C  +  G  CE C  G+     +   C P
Sbjct: 153 VTGACHCTYNTSGLNCEICHMGYEGDALHLKNCAP 257

 Score = 38.5 bits (88), Expect = 0.063,   Method: Composition-based stats.
 Identities = 22/64 (34%), Positives = 30/64 (46%), Gaps = 2/64 (3%)
 Frame = +3

Query: 925 GRRCEQCQPGFYSSPSNATGCLPCLCHTAGAVSH--ICNSVTGQCSCHDPSTTGRSCHQC 982
           G  C  C  G+Y    +   C+PC CH     S   +C+ VTG C C   +T+G +C  C
Sbjct: 42  GNICHMCAYGYYL---HQKFCVPCHCHNNHNRSRPFMCDMVTGACHC-TYNTSGLNCEIC 209

Query: 983 QESY 986
              Y
Sbjct: 210 HMGY 221

 Score = 34.7 bits (78), Expect = 1.0,   Method: Composition-based stats.
 Identities = 23/68 (33%), Positives = 28/68 (41%), Gaps = 2/68 (2%)
 Frame = +3

Query: 765 CKKEAKGLKCDSCRENFYGLPWSACEVCDC--SKAGSQPGTVCDTETGQCVCKPNVGGRQ 822
           C+    G  C  C   +Y L    C  C C  +   S+P  +CD  TG C C  N  G  
Sbjct: 24  CEVGYTGNICHMCAYGYY-LHQKFCVPCHCHNNHNRSRP-FMCDMVTGACHCTYNTSGLN 197

Query: 823 CSQCKAGY 830
           C  C  GY
Sbjct: 198 CEICHMGY 221
>26039
          Length = 441

 Score = 45.4 bits (106), Expect = 6e-04,   Method: Compositional matrix adjust.
 Identities = 41/110 (37%), Positives = 53/110 (48%), Gaps = 3/110 (2%)
 Frame = -1

Query: 863 GQCPCKLGVTGLRCHQ-CKPHRFNLTMDNPQGCQACDCDSLGTLPGSMCDPISGQCLCLP 921
           G+C CK G TG+RC + C+P  F     +      C C   G      CDP++G C+C  
Sbjct: 375 GRCICKPGWTGMRCSEHCRPGTFGAECKH-----NCSCSQHGE-----CDPVTGACICQR 226

Query: 922 HRQGRRCEQ-CQPGFYSSPSNATGCL-PCLCHTAGAVSHICNSVTGQCSC 969
             +G  C Q CQ G+Y       GC   CLC     VS  C+ VTG C+C
Sbjct: 225 GYRGTTCNQTCQAGWY-----GIGCRHQCLCEEHNTVS--CDHVTGVCTC 97

 Score = 38.9 bits (89), Expect = 0.051,   Method: Compositional matrix adjust.
 Identities = 44/137 (32%), Positives = 63/137 (45%), Gaps = 10/137 (7%)
 Frame = -1

Query: 810 GQCVCKPNVGGRQCSQ-CKAGYFNLYQNDSHLCLTCNCEKMGTVNGSLRCDKSTGQCPCK 868
           G+C+CKP   G +CS+ C+ G F      +     C+C + G       CD  TG C C+
Sbjct: 375 GRCICKPGWTGMRCSEHCRPGTFGAECKHN-----CSCSQHG------ECDPVTGACICQ 229

Query: 869 LGVTGLRCHQ-CKPHRFNLTMDNPQGCQ-ACDCDSLGTLPGSMCDPISGQCLC----LPH 922
            G  G  C+Q C+   + +      GC+  C C+   T+    CD ++G C C       
Sbjct: 228 RGYRGTTCNQTCQAGWYGI------GCRHQCLCEEHNTVS---CDHVTGVCTCKHLYTVS 76

Query: 923 RQGRRCEQ---CQPGFY 936
             G RCE+   C PGFY
Sbjct: 75  CSGLRCEEKASCPPGFY 25

 Score = 37.4 bits (85), Expect = 0.15,   Method: Compositional matrix adjust.
 Identities = 34/110 (30%), Positives = 54/110 (49%), Gaps = 2/110 (1%)
 Frame = -1

Query: 708 NSGQCSCKANVIGLRCNR-CNFGFKFLQSFNGDGCEPCQCNLHGSVNQLCDPLSGQCACK 766
           ++G+C CK    G+RC+  C  G     +F  +    C C+ HG     CDP++G C C+
Sbjct: 381 HNGRCICKPGWTGMRCSEHCRPG-----TFGAECKHNCSCSQHGE----CDPVTGACICQ 229

Query: 767 KEAKGLKCD-SCRENFYGLPWSACEVCDCSKAGSQPGTVCDTETGQCVCK 815
           +  +G  C+ +C+  +YG+       C C +  +     CD  TG C CK
Sbjct: 228 RGYRGTTCNQTCQAGWYGIGCR--HQCLCEEHNT---VSCDHVTGVCTCK 94

 Score = 33.9 bits (76), Expect = 1.8,   Method: Compositional matrix adjust.
 Identities = 30/78 (38%), Positives = 38/78 (48%), Gaps = 6/78 (7%)
 Frame = -1

Query: 652 CDPIGGQCDCKRRVSGRQCLQ-CQDGFYDLQALDPDGCR-PCNCNPSGTVDGDITCHQNS 709
           CDP+ G C C+R   G  C Q CQ G+Y +      GCR  C C    TV    +C   +
Sbjct: 261 CDPVTGACICQRGYRGTTCNQTCQAGWYGI------GCRHQCLCEEHNTV----SCDHVT 112

Query: 710 GQCSCK----ANVIGLRC 723
           G C+CK     +  GLRC
Sbjct: 111 GVCTCKHLYTVSCSGLRC 58

 Score = 31.6 bits (70), Expect = 9.5,   Method: Compositional matrix adjust.
 Identities = 36/115 (31%), Positives = 49/115 (42%), Gaps = 3/115 (2%)
 Frame = -1

Query: 914  SGQCLCLPHRQGRRC-EQCQPGFYSSPSNATGCLPCLCHTAGAVSH-ICNSVTGQCSCHD 971
            +G+C+C P   G RC E C+PG + +            H      H  C+ VTG C C  
Sbjct: 378  NGRCICKPGWTGMRCSEHCRPGTFGAECK---------HNCSCSQHGECDPVTGACICQR 226

Query: 972  PSTTGRSCHQ-CQESYFRFDPLTGRCRPCHCHVAGASNGTCDAVTGQCFCKEFVT 1025
                G +C+Q CQ  ++        CR   C     +  +CD VTG C CK   T
Sbjct: 225  -GYRGTTCNQTCQAGWYGIG-----CRH-QCLCEEHNTVSCDHVTGVCTCKHLYT 82
>27883
          Length = 862

 Score = 43.9 bits (102), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 47/201 (23%), Positives = 88/201 (43%), Gaps = 14/201 (6%)
 Frame = -1

Query: 329 MSRLNPEAHPLSFINDDDVATSWISHVFTN----ITQLYEGVAISIDLENGQYQVLKVIT 384
           + R N E+H +     +++ +S+  H   N         E V+I + LE  ++    +I 
Sbjct: 565 IERQNEESHLV-----ENIVSSFRGHRRRNRWWQAVNGEENVSIQLKLE-AEFHFTHLIM 404

Query: 385 QFSSLQPVAIRIQRKKADSSPWEDWQYFARNC--SVWGMKDNEDLENPNSVNCLQLPDFI 442
            F + +P A+ I+R       W  ++YFA NC  S  G+         + +   +  +  
Sbjct: 403 TFKTFRPKAMLIERSYDFGKTWAVYRYFAENCARSFPGVSVGPVHSLADVICEEKYSEET 224

Query: 443 PFSHGNVTFDLLTSGQKHRPGY---NDFYNSSVLQEFMRATQIRLHFHGQYYPAGHTVDW 499
           P S G V F +L       P +    D Y+ +V Q+ ++ T +R++F   +      +D 
Sbjct: 223 PSSGGEVIFRVL-------PPFIPIADPYSEAV-QDLLKLTDLRVNFTELHTLGDTLLDS 68

Query: 500 RHQ-----YYAVDEIIVSGRC 515
           R +     YY++ ++ V G C
Sbjct: 67  RSEIKEKYYYSLYDMTVRGSC 5
>23938
          Length = 774

 Score = 39.3 bits (90), Expect = 0.041,   Method: Composition-based stats.
 Identities = 24/73 (32%), Positives = 33/73 (45%), Gaps = 1/73 (1%)
 Frame = -2

Query: 3257 ACCGTMPYATSGSQVCCAGRLQ-DGYRQQCCGGEMVSQDFQCCGGGEEGMVYSYLPGMLC 3315
            ACCG   Y T   ++CCAG++   G    CC  E  ++  Q C  GE   V+       C
Sbjct: 773  ACCGNEAYNTR-REICCAGKVNLKGRSNACCKTEAYTRGRQICCDGE---VHLKGRNNAC 606

Query: 3316 CGQDYVNMSETIC 3328
            CG    N   ++C
Sbjct: 605  CGTQPYNTRRSVC 567

 Score = 38.5 bits (88), Expect = 0.079,   Method: Composition-based stats.
 Identities = 25/76 (32%), Positives = 35/76 (46%), Gaps = 1/76 (1%)
 Frame = -2

Query: 3228 CSGHYARILPGEICCPDERHNRVSVGFGDACCGTMPYATSGSQVCCAGRLQ-DGYRQQCC 3286
            C G+ A     EICC  + + +   G  +ACC T  Y T G Q+CC G +   G    CC
Sbjct: 770  CCGNEAYNTRREICCAGKVNLK---GRSNACCKTEAY-TRGRQICCDGEVHLKGRNNACC 603

Query: 3287 GGEMVSQDFQCCGGGE 3302
            G +  +     C  G+
Sbjct: 602  GTQPYNTRRSVCREGQ 555

 Score = 38.1 bits (87), Expect = 0.091,   Method: Composition-based stats.
 Identities = 24/67 (35%), Positives = 33/67 (49%)
 Frame = -2

Query: 3212 VCCGGRMWEAQPDHQCCSGHYARILPGEICCPDERHNRVSVGFGDACCGTMPYATSGSQV 3271
            +CC G++      + CC    A     +ICC  E H +   G  +ACCGT PY T  S V
Sbjct: 734  ICCAGKVNLKGRSNACCKTE-AYTRGRQICCDGEVHLK---GRNNACCGTQPYNTRRS-V 570

Query: 3272 CCAGRLQ 3278
            C  G++ 
Sbjct: 569  CREGQVH 549
>18367
          Length = 460

 Score = 38.9 bits (89), Expect = 0.055,   Method: Compositional matrix adjust.
 Identities = 33/104 (31%), Positives = 42/104 (40%), Gaps = 11/104 (10%)
 Frame = +1

Query: 601 VCDDCQHHTTGRHCESCQDYFYRPVGADP--AAPDACKLCDCN--------RAGTRNGSL 650
            C  C+H+T G +CE CQ  FY     DP       C+ C C             R    
Sbjct: 1   ACQACKHNTMGHNCELCQPGFY----GDPRQGTDKDCQTCACPLMTGNNFFAESCRANPT 168

Query: 651 HCDPIGGQC-DCKRRVSGRQCLQCQDGFYDLQALDPDGCRPCNC 693
             D  G QC +C++   G  C +C  G+Y        GCR CNC
Sbjct: 169 ATDRAGYQCVNCQQGYEGDHCQRCSTGYYGNPLQPGGGCRRCNC 300

 Score = 37.7 bits (86), Expect = 0.13,   Method: Compositional matrix adjust.
 Identities = 38/122 (31%), Positives = 48/122 (39%), Gaps = 19/122 (15%)
 Frame = +1

Query: 661 CKRRVSGRQCLQCQDGFYD--LQALDPDGCRPCNC---------------NPSGTVDGDI 703
           CK    G  C  CQ GFY    Q  D D C+ C C               NP+ T     
Sbjct: 13  CKHNTMGHNCELCQPGFYGDPRQGTDKD-CQTCACPLMTGNNFFAESCRANPTATDRAGY 189

Query: 704 TCHQNSGQCSCKANVIGLRCNRCNFGFKFLQSFNGDGCEPCQC--NLHGSVNQLCDPLSG 761
            C       +C+    G  C RC+ G+       G GC  C C  N++ SV   CDP++G
Sbjct: 190 QCV------NCQQGYEGDHCQRCSTGYYGNPLQPGGGCRRCNCGGNINLSVPGSCDPVTG 351

Query: 762 QC 763
            C
Sbjct: 352 AC 357

 Score = 37.0 bits (84), Expect = 0.21,   Method: Compositional matrix adjust.
 Identities = 37/121 (30%), Positives = 50/121 (41%), Gaps = 20/121 (16%)
 Frame = +1

Query: 919  CLPHRQGRRCEQCQPGFYSSPSNAT--GCLPCLCHTAGAVSHICNSVTGQCSCHDPSTTG 976
            C  +  G  CE CQPGFY  P   T   C  C C      +    S        +P+ T 
Sbjct: 13   CKHNTMGHNCELCQPGFYGDPRQGTDKDCQTCACPLMTGNNFFAESCRA-----NPTATD 177

Query: 977  RS---CHQCQESY-----------FRFDPLT--GRCRPCHC--HVAGASNGTCDAVTGQC 1018
            R+   C  CQ+ Y           +  +PL   G CR C+C  ++  +  G+CD VTG C
Sbjct: 178  RAGYQCVNCQQGYEGDHCQRCSTGYYGNPLQPGGGCRRCNCGGNINLSVPGSCDPVTGAC 357

Query: 1019 F 1019
             
Sbjct: 358  V 360

 Score = 36.6 bits (83), Expect = 0.29,   Method: Compositional matrix adjust.
 Identities = 37/118 (31%), Positives = 52/118 (44%), Gaps = 12/118 (10%)
 Frame = +1

Query: 813 VCKPNVGGRQCSQCKAGYF-NLYQNDSHLCLTCNCEKMGTVN---GSLRC-----DKSTG 863
            CK N  G  C  C+ G++ +  Q     C TC C  M   N    S R      D++  
Sbjct: 10  ACKHNTMGHNCELCQPGFYGDPRQGTDKDCQTCACPLMTGNNFFAESCRANPTATDRAGY 189

Query: 864 QC-PCKLGVTGLRCHQCKPHRFNLTMDNPQGCQACDCDSLGTL--PGSMCDPISGQCL 918
           QC  C+ G  G  C +C    +   +    GC+ C+C     L  PGS CDP++G C+
Sbjct: 190 QCVNCQQGYEGDHCQRCSTGYYGNPLQPGGGCRRCNCGGNINLSVPGS-CDPVTGACV 360

 Score = 36.2 bits (82), Expect = 0.36,   Method: Compositional matrix adjust.
 Identities = 36/118 (30%), Positives = 47/118 (39%), Gaps = 16/118 (13%)
 Frame = +1

Query: 764 ACKKEAKGLKCDSCRENFYGLPWSA----CEVCDC---------SKAGSQPGTVCDTETG 810
           ACK    G  C+ C+  FYG P       C+ C C         +++     T  D    
Sbjct: 10  ACKHNTMGHNCELCQPGFYGDPRQGTDKDCQTCACPLMTGNNFFAESCRANPTATDRAGY 189

Query: 811 QCV-CKPNVGGRQCSQCKAGYFNLYQNDSHLCLTCNCEKMGTVNGSL--RCDKSTGQC 865
           QCV C+    G  C +C  GY+         C  CNC   G +N S+   CD  TG C
Sbjct: 190 QCVNCQQGYEGDHCQRCSTGYYGNPLQPGGGCRRCNCG--GNINLSVPGSCDPVTGAC 357

 Score = 35.0 bits (79), Expect = 0.88,   Method: Compositional matrix adjust.
 Identities = 35/122 (28%), Positives = 51/122 (41%), Gaps = 3/122 (2%)
 Frame = +1

Query: 541 TEGPQCDRCSPLYNDKPFRSGDNVNAFNCKPCQCHGHASSCHYDASVDPFPLEHNRGGGG 600
           T G  C+ C P +   P +  D     +C+ C C     +  +  S    P   +R G  
Sbjct: 25  TMGHNCELCQPGFYGDPRQGTDK----DCQTCACPLMTGNNFFAESCRANPTATDRAGY- 189

Query: 601 VCDDCQHHTTGRHCESCQDYFYRPVGADPAAP-DACKLCDCNRAGTRNGSL--HCDPIGG 657
            C +CQ    G HC+ C   +Y     +P  P   C+ C+C   G  N S+   CDP+ G
Sbjct: 190 QCVNCQQGYEGDHCQRCSTGYY----GNPLQPGGGCRRCNC--GGNINLSVPGSCDPVTG 351

Query: 658 QC 659
            C
Sbjct: 352 AC 357
>25554
          Length = 435

 Score = 37.4 bits (85), Expect = 0.17,   Method: Composition-based stats.
 Identities = 34/126 (26%), Positives = 44/126 (34%), Gaps = 25/126 (19%)
 Frame = -3

Query: 4810 TAELRTHPAPPSGLSPPQVQTLGSRMASVHWTPPLLPNGVIHSYELQL--QRAC------ 4861
            T   R    P   +S   +   GSR  +V W  P  PNG I  Y +QL     C      
Sbjct: 406  TDRFRVQTKPAGVVSSLTLNKFGSRWINVTWRKPDNPNGNISGYTIQLLSNNVCKSGVTV 227

Query: 4862 --------PPDSAPRCPP-SHTERKYWGPGHRAS--------LAGLQPNTAYGVQVVAYN 4904
                    P + AP      H E   +     A+        +  L+P+  Y   V AYN
Sbjct: 226  NCSDCFGDPKEMAPNITSCEHNETMVFTKDQLANGDFNVTIYVTELKPDVVYTTIVTAYN 47

Query: 4905 EAGSTA 4910
            E G  A
Sbjct: 46   EQGGGA 29

 Score = 32.0 bits (71), Expect = 6.6,   Method: Composition-based stats.
 Identities = 15/42 (35%), Positives = 21/42 (50%), Gaps = 1/42 (2%)
 Frame = -3

Query: 3855 LEAAPVGLMPPL-LKALGSSCIEVKWMPPTRPNGIITSYVVH 3895
            ++  P G++  L L   GS  I V W  P  PNG I+ Y + 
Sbjct: 391  VQTKPAGVVSSLTLNKFGSRWINVTWRKPDNPNGNISGYTIQ 266
>26607
          Length = 405

 Score = 35.8 bits (81), Expect = 0.49,   Method: Compositional matrix adjust.
 Identities = 18/70 (25%), Positives = 33/70 (47%), Gaps = 2/70 (2%)
 Frame = +2

Query: 1790 KWNTVSIKKEGSVVSVRVNALKKSTSQAGGQP--LLVNSPVYLGGIPRELQDAYRHLTLE 1847
            +W  V + +      +RV    +  ++A G P  L + +P+Y+GG  R      R + + 
Sbjct: 50   RWTRVELLRRQGESILRVGDEAEQRAKAAGAPRTLSLKTPLYIGGYDRANVKINRDVNIT 229

Query: 1848 PGFRGCVKEV 1857
             GF GC+  +
Sbjct: 230  DGFDGCISRL 259
>35879
          Length = 389

 Score = 35.4 bits (80), Expect = 0.64,   Method: Compositional matrix adjust.
 Identities = 20/49 (40%), Positives = 27/49 (55%)
 Frame = +2

Query: 1902 GSQQSVYESGLQPFTEYLYRVTASHEGGAVSSDWSRGRTLGTAPQSVPT 1950
            GS +S   +GL PFT Y+  + A    G+     + GRTL   PQ+VPT
Sbjct: 80   GSMRSYNLTGLLPFTTYVVTIRAFSPKGSSIHYSAEGRTLEGVPQAVPT 226

 Score = 32.0 bits (71), Expect = 6.1,   Method: Compositional matrix adjust.
 Identities = 16/50 (32%), Positives = 24/50 (48%)
 Frame = +2

Query: 3627 TDTSDRRQHTVTGLQPYTNYSFTLAVCTSVGCTSSEPCVGQTLQAAPQGV 3676
            T     R + +TGL P+T Y  T+   +  G +      G+TL+  PQ V
Sbjct: 71   TVVGSMRSYNLTGLLPFTTYVVTIRAFSPKGSSIHYSAEGRTLEGVPQAV 220
>11667
          Length = 1227

 Score = 34.7 bits (78), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 22/54 (40%), Positives = 28/54 (51%), Gaps = 2/54 (3%)
 Frame = +3

Query: 914 SGQCLCLPHRQGRRCEQCQPGFYSSPSNATGCLPCLCHTAGAVSHI-C-NSVTG 965
           SG+C C    +G+ C+ C+ G+Y S  N T       HT   V HI C NS TG
Sbjct: 309 SGKCKCTAGYEGKLCDSCKAGYYQSEKNDT-------HTVCKVCHISCKNSCTG 449

 Score = 33.9 bits (76), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 19/53 (35%), Positives = 29/53 (54%), Gaps = 1/53 (1%)
 Frame = +3

Query: 794 CSKAGSQPGTVCDTETGQCVCKPNVGGRQCSQCKAGYFNLYQNDSH-LCLTCN 845
           C  AG++ G+      G+C C     G+ C  CKAGY+   +ND+H +C  C+
Sbjct: 282 CLGAGTREGS------GKCKCTAGYEGKLCDSCKAGYYQSEKNDTHTVCKVCH 422
>31203
          Length = 1813

 Score = 32.7 bits (73), Expect = 4.2,   Method: Composition-based stats.
 Identities = 94/414 (22%), Positives = 136/414 (32%), Gaps = 101/414 (24%)
 Frame = -3

Query: 617  CQDYFYRPVGADPAAPDACKLCDCNRAGTRNGSLHCD-PIGGQCDCK------------- 662
            CQ  FY+  G      DA +   C   G  N +  C  P GG C C              
Sbjct: 1298 CQTGFYKDKGKCEQLKDAGE--KCTGLGQCNLNAECSTPYGGLCTCDDTFYNSNGQCKPL 1125

Query: 663  ----RRVSGR-QCL-------------QCQDGFYDLQALDPDGCRPCN-CNPSGTVDGDI 703
                R  +G+ QCL              C  GFYD   +     +P   C+  G     +
Sbjct: 1124 EKAGRPCTGKGQCLGKAECSSNIKGVCTCIIGFYDQDGICLKAKKPQERCDAPGNALSTL 945

Query: 704  TCHQNSGQCSCKANVI-----------------GLR-------CN-------RCNFGF-- 730
                  G C C+ + +                 GLR       C         CN GF  
Sbjct: 944  LVLLPQGICECRPSFVEKKGECVPAIPAGDPCSGLRECVENAECTTAMGGLCECNDGFYI 765

Query: 731  ---KFLQSFNGDGCEPCQCNLHGSVNQLCDPLSGQCACKKEAKGLKCDSCRENFYGLPWS 787
               K + S       PC   L    N +C P +G C C+ +   LK +  ++     P  
Sbjct: 764  DNKKCIPSIKVH--NPCVETLQCVSNAVCTPETGTCECRDDYFPLKGNCEKKKKASEPCG 591

Query: 788  ACEVC-DCSKAGSQPGTVC---------------DTE-----TGQCVCKPNVGGRQCSQC 826
                C D ++  S  G +C                TE     TG+  C PN    +  +C
Sbjct: 590  GYGQCVDNAECNSPQGGLCLCHEGFFENDGACRTQTELGKACTGEEECTPNSVCVETCRC 411

Query: 827  KAGYFNLYQNDSHLCLT-------CNCEKMGTVNGSLRCDKSTGQCPCKLGVTGLRCHQC 879
            + GYF     D  LC         C+ + M ++   +   +  G C C+ G    +  QC
Sbjct: 410  REGYF----KDKGLCYEKKLVGDPCSFDDMCSL-WMICSSEINGFCICQDGFFE-QNRQC 249

Query: 880  KPHRFNLTMDNPQGCQACDCDSLGT--LPGSMCDPISGQCLCLP--HRQGRRCE 929
                       P G +   C  LG   +     +P  G C CLP  +R+ + C+
Sbjct: 248  GGRI-------PPGEE---CQELGACVINAECSNPSGGICQCLPDFYREDKECK 117
>11044
          Length = 501

 Score = 31.6 bits (70), Expect = 7.7,   Method: Composition-based stats.
 Identities = 12/20 (60%), Positives = 13/20 (65%)
 Frame = -1

Query: 711 QCSCKANVIGLRCNRCNFGF 730
           QCSCK N  GL C RC  G+
Sbjct: 501 QCSCKGNFAGLDCRRCAAGY 442
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|19527116|ref|NP_598661.1| phosphoserine phosphatase
[Mus musculus]
         (225 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

38655                                                                  90   6e-19
25866                                                                  27   4.7  
29946                                                                  27   5.4  
>38655
          Length = 265

 Score = 90.1 bits (222), Expect = 6e-19,   Method: Compositional matrix adjust.
 Identities = 38/59 (64%), Positives = 48/59 (81%)
 Frame = -2

Query: 166 KEKFHFKKIIMIGDGATDMEACPPADAFIGFGGNVIRQQVKDNAKWYITDFVELLGELE 224
           KEK+ F+ + MIGDGATDMEA PPADAFIG+GGNV+R+ VK  A W++TDF EL+  L+
Sbjct: 264 KEKYGFQTLTMIGDGATDMEAAPPADAFIGYGGNVVRESVKQKAAWFVTDFKELISALK 88
>25866
          Length = 422

 Score = 27.3 bits (59), Expect = 4.7,   Method: Compositional matrix adjust.
 Identities = 17/64 (26%), Positives = 29/64 (45%)
 Frame = +3

Query: 86  HLTPGIRELVSRLQERNVQVFLISGGFRSIVEHVAAKLNIPTTNVFANRLKFYFNGEYAG 145
            LTP +R+LV     R   V  ++   +   +HV+ +  +P        +    NG+ A 
Sbjct: 216 QLTPMLRDLVLTRMGRYNDVATVAEAKKRFQQHVSGEKTLPADLRGPVYITVLTNGDAAV 395

Query: 146 FDEM 149
           FD+M
Sbjct: 396 FDQM 407
>29946
          Length = 1192

 Score = 27.3 bits (59), Expect = 5.4,   Method: Compositional matrix adjust.
 Identities = 21/65 (32%), Positives = 31/65 (47%), Gaps = 7/65 (10%)
 Frame = -1

Query: 58  FKDALTQRLALIQPSRD-QVQRLLAE-----HPPHLTPGIRELVSRLQERNVQVFLIS-G 110
             DA  Q L    P  D Q+   ++E     HPPHL    +E++  + ER +QV L   G
Sbjct: 994 LYDATAQHLQPAAPVLDLQLPGRVSEGEVLVHPPHLYVMSKEMLGEIHERLLQVVLQQFG 815

Query: 111 GFRSI 115
           G  ++
Sbjct: 814 GLHAV 800
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|15808988|ref|NP_291039.1| eukaryotic translation
initiation factor 4H [Mus musculus]
         (248 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

12593                                                                  66   7e-19
10194                                                                  56   1e-08
00673                                                                  55   3e-08
04730                                                                  54   5e-08
31310                                                                  42   3e-04
28455                                                                  40   7e-04
16016                                                                  40   0.001
23322                                                                  38   0.004
03000                                                                  38   0.004
02140                                                                  38   0.004
11687                                                                  38   0.005
26197                                                                  37   0.008
25950                                                                  37   0.008
03406                                                                  36   0.014
17681                                                                  36   0.019
11126                                                                  35   0.020
02343                                                                  31   0.37 
39789                                                                  31   0.40 
30672                                                                  31   0.43 
33504                                                                  31   0.54 
01278                                                                  31   0.54 
12506                                                                  30   0.71 
00556                                                                  30   0.83 
>12593
          Length = 462

 Score = 66.2 bits (160), Expect(2) = 7e-19,   Method: Compositional matrix adjust.
 Identities = 29/45 (64%), Positives = 37/45 (82%)
 Frame = +1

Query: 41 PYTAYVGNLPFNTVQGDIDAIFKDLSIRSVRLVRDKDTDKFKGFC 85
           YTAYVGNLP   VQGD++ IFKDL +++VRLVRD++TD+FK  C
Sbjct: 1  SYTAYVGNLPDGLVQGDLELIFKDLKVKTVRLVRDRETDRFKRVC 135

 Score = 44.7 bits (104), Expect(2) = 7e-19,   Method: Compositional matrix adjust.
 Identities = 20/30 (66%), Positives = 26/30 (86%)
 Frame = +2

Query: 82  KGFCYVEFDEVDSLKEALTYDGALLGDRSL 111
           KGF YVEF++ DSL+EALTY+GAL  D++L
Sbjct: 125 KGFAYVEFEDPDSLQEALTYNGALFEDKNL 214

 Score = 51.6 bits (122), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 27/52 (51%), Positives = 35/52 (67%), Gaps = 2/52 (3%)
 Frame = +3

Query: 193 SNMDFREPTEEERAQRPRLQLKPRTVATPLNQVANP--NSAIFGGARPREEV 242
           ++ + REP+ E   +RPRL+L PRTVA PLN  A    NS+IFG  RPR+E 
Sbjct: 210 TSQELREPSPESATRRPRLKLLPRTVAAPLNTPAETSRNSSIFGKGRPRDEA 365
>10194
          Length = 1278

 Score = 56.2 bits (134), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 26/72 (36%), Positives = 44/72 (61%), Gaps = 1/72 (1%)
 Frame = -3

Query: 43  TAYVGNLPFNTVQGDIDAIFKDLS-IRSVRLVRDKDTDKFKGFCYVEFDEVDSLKEALTY 101
           + +VGNLPF+  +  + + F+D   + ++R+VRD+ T+  KG CY+ F   DS+  AL  
Sbjct: 403 SVFVGNLPFDIEEESVRSHFEDCGDVENIRVVRDRKTNLGKGICYILFKSADSVSLALKL 224

Query: 102 DGALLGDRSLRV 113
           + + L  R +RV
Sbjct: 223 NNSELEKRQIRV 188

 Score = 35.8 bits (81), Expect = 0.016,   Method: Compositional matrix adjust.
 Identities = 25/93 (26%), Positives = 42/93 (45%), Gaps = 18/93 (19%)
 Frame = -3

Query: 43  TAYVGNLPFNTVQGDIDAIFKDL-SIRSVR-----------------LVRDKDTDKFKGF 84
           T +VGN+P  T +  +  +FK    I +VR                 + +D    +    
Sbjct: 709 TVFVGNVPLKTDKKKLARLFKQFGKIENVRFRCAPVGDPTTKKRVAVITKDFHEKRHNIS 530

Query: 85  CYVEFDEVDSLKEALTYDGALLGDRSLRVDIAE 117
            Y+ F E ++ K+ALT +G ++    LRVD A+
Sbjct: 529 AYICFKEDEAAKQALTLNGHVIDGLHLRVDSAK 431
>00673
          Length = 3471

 Score = 55.1 bits (131), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 28/52 (53%), Positives = 37/52 (71%), Gaps = 2/52 (3%)
 Frame = -3

Query: 192  GSNMDFREPTEEERAQRPRLQLKPRTVATPLNQVANP--NSAIFGGARPREE 241
            G++ + REP+ E  A+RPRL+L PRTVA P N  A+   NS+IFG  +PREE
Sbjct: 3238 GASQELREPSPESAARRPRLKLLPRTVAAPANAPADGSRNSSIFGSGKPREE 3083
>04730
          Length = 3883

 Score = 53.9 bits (128), Expect = 5e-08,   Method: Compositional matrix adjust.
 Identities = 28/53 (52%), Positives = 36/53 (67%), Gaps = 2/53 (3%)
 Frame = +3

Query: 192 GSNMDFREPTEEERAQRPRLQLKPRTVATPLNQVANP--NSAIFGGARPREEV 242
           G++ + REP+ E   +RPRL+L PRTVA PLN  A    NS+IFG  RPR+E 
Sbjct: 144 GASQELREPSPESATRRPRLKLLPRTVAAPLNTPAETSRNSSIFGKGRPRDEA 302
>31310
          Length = 469

 Score = 41.6 bits (96), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 24/71 (33%), Positives = 41/71 (57%), Gaps = 2/71 (2%)
 Frame = -3

Query: 45  YVGNLPFNTVQGDIDAIFKDLS-IRSVRLVRDKDTDKFKGFCYVEFDEVDSLKEAL-TYD 102
           YVG++ F   +  I   F     I+SV L  D  T+K KGF ++E+D  ++ + AL   +
Sbjct: 314 YVGSINFEIREDTIKQAFLPFGPIKSVNLSWDPITNKHKGFSFIEYDVPEAAQLALEQMN 135

Query: 103 GALLGDRSLRV 113
           G ++G R+++V
Sbjct: 134 GVMIGGRNIKV 102
>28455
          Length = 573

 Score = 40.4 bits (93), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 25/74 (33%), Positives = 40/74 (54%), Gaps = 2/74 (2%)
 Frame = -1

Query: 45  YVGNLPFNTVQGDIDAIFKDL-SIRSVRLVRDKDTDKFKGFCYVEFDEVDSLKEA-LTYD 102
           +V NLPF      ++ IFK+   ++ VRLV  + +   KG  YVEF+  +   +A +  D
Sbjct: 531 FVKNLPFTCSAEALETIFKEHGKVKDVRLVTYR-SGASKGLAYVEFETEEMATQAVMKTD 355

Query: 103 GALLGDRSLRVDIA 116
           G  +GD  + V I+
Sbjct: 354 GLQVGDHMISVAIS 313
>16016
          Length = 1364

 Score = 39.7 bits (91), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 14/47 (29%), Positives = 27/47 (57%)
 Frame = -1

Query: 70  VRLVRDKDTDKFKGFCYVEFDEVDSLKEALTYDGALLGDRSLRVDIA 116
           + +++DK T KF+GFC+V FD+ D++ +   +    +  R +    A
Sbjct: 965 INMIKDKSTGKFRGFCFVSFDDCDTVDKHAIHKCFKINGRHVEAKKA 825
>23322
          Length = 471

 Score = 38.1 bits (87), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 24/76 (31%), Positives = 40/76 (52%), Gaps = 1/76 (1%)
 Frame = -2

Query: 45  YVGNLPFNTVQGDIDAIFKDLS-IRSVRLVRDKDTDKFKGFCYVEFDEVDSLKEALTYDG 103
           +VG +  +T +  I   F +   I  V L++DK T K +GFC+V F + DS+ +A+    
Sbjct: 401 FVGGVKEDTTEDMIRDTFNEFGEITGVDLIQDKGTGKNRGFCFVTFGDHDSVDKAVLKKR 222

Query: 104 ALLGDRSLRVDIAEGR 119
             L  R + V  A+ +
Sbjct: 221 HDLNGRQVEVKKAQSK 174
>03000
          Length = 778

 Score = 37.7 bits (86), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 24/76 (31%), Positives = 40/76 (52%), Gaps = 1/76 (1%)
 Frame = +3

Query: 45  YVGNLPFNTVQGDIDAIFKDL-SIRSVRLVRDKDTDKFKGFCYVEFDEVDSLKEALTYDG 103
           +VG +  +T +  I   F +   I  V L++DK T K +GFC+V F + DS+ +A+    
Sbjct: 369 FVGGVKEDTTEDMIRDTFNEFGEITGVDLIQDKGTGKNRGFCFVTFGDHDSVDKAVLKKR 548

Query: 104 ALLGDRSLRVDIAEGR 119
             L  R + V  A+ +
Sbjct: 549 HDLNGRQVEVKKAQSK 596
>02140
          Length = 1796

 Score = 37.7 bits (86), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 28/100 (28%), Positives = 48/100 (48%), Gaps = 3/100 (3%)
 Frame = +3

Query: 38  TEPP-YTAYVGNLPFNTVQGDIDAIFKDLS-IRSVRLVRDKDTDKFKGFCYVEFDEVDSL 95
           T+PP    +V  L   T   D++ IF     I S  ++RD  T +   + +VEF++ +  
Sbjct: 786 TKPPDNVLFVCKLNPVTTDEDLEMIFSRFGPITSCEVIRDHKTKESLQYAFVEFEKPEHC 965

Query: 96  KEA-LTYDGALLGDRSLRVDIAEGRKQDKGGFGFRKGGPD 134
           + A    D  L+ DR + VD ++   + +   G +KG  D
Sbjct: 966 ENAYFKMDNVLIDDRRIHVDFSQSVSKIRPMDGQKKGEED 1085
>11687
          Length = 676

 Score = 37.7 bits (86), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 21/68 (30%), Positives = 39/68 (57%), Gaps = 1/68 (1%)
 Frame = +3

Query: 45  YVGNLPFNTVQGDIDAIFKDLS-IRSVRLVRDKDTDKFKGFCYVEFDEVDSLKEALTYDG 103
           +VG +P N  + ++  +F+D   + S+ ++RDK+T + KG C+V F    + K AL    
Sbjct: 159 FVGQIPRNMDENELRKMFEDYGPVHSLNILRDKNTGQSKGCCFVTF---FTRKAALDAQN 329

Query: 104 ALLGDRSL 111
           AL   +++
Sbjct: 330 ALHNVKTM 353
>26197
          Length = 1365

 Score = 37.0 bits (84), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 21/70 (30%), Positives = 37/70 (52%), Gaps = 1/70 (1%)
 Frame = -3

Query: 45   YVGNLPFNTVQGDIDAIFKDL-SIRSVRLVRDKDTDKFKGFCYVEFDEVDSLKEALTYDG 103
            +VG L     Q D+++ F     + +V L  DK  D+ + FC+VEFD   ++K+ L    
Sbjct: 1042 FVGKLDPGVPQEDVESYFAKFGKVVNVELPYDKVKDQRRAFCFVEFDNDKTVKKVLEQTS 863

Query: 104  ALLGDRSLRV 113
              +G + +R+
Sbjct: 862  HKIGGQEVRI 833
>25950
          Length = 417

 Score = 37.0 bits (84), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 20/72 (27%), Positives = 37/72 (51%), Gaps = 1/72 (1%)
 Frame = -2

Query: 43  TAYVGNLPFNTVQGDIDAIFKDL-SIRSVRLVRDKDTDKFKGFCYVEFDEVDSLKEALTY 101
           + YVGN+ +     +++A F    +I  V ++ +K     KGF Y+EF   + ++ AL  
Sbjct: 278 SVYVGNVDYGASAEELEAHFHGCGTINRVTILCNKADGHPKGFAYIEFGSKEYVETALAM 99

Query: 102 DGALLGDRSLRV 113
           +  L   R ++V
Sbjct: 98  NETLFRGRQIKV 63
>03406
          Length = 1292

 Score = 36.2 bits (82), Expect = 0.014,   Method: Compositional matrix adjust.
 Identities = 22/73 (30%), Positives = 37/73 (50%), Gaps = 1/73 (1%)
 Frame = +3

Query: 45  YVGNLPFNTVQGDIDAIFKDL-SIRSVRLVRDKDTDKFKGFCYVEFDEVDSLKEALTYDG 103
           +VG L     Q D+++ F     + +V L  DK  D+ + FC+VEFD   ++K+ L    
Sbjct: 495 FVGKLDPGVPQEDVESYFAKFGKVVNVELPYDKVKDQRRAFCFVEFDNDKTVKKVLEQTS 674

Query: 104 ALLGDRSLRVDIA 116
             +G + + V  A
Sbjct: 675 HKIGGQEVDVKKA 713
>17681
          Length = 964

 Score = 35.8 bits (81), Expect = 0.019,   Method: Compositional matrix adjust.
 Identities = 17/49 (34%), Positives = 28/49 (57%), Gaps = 1/49 (2%)
 Frame = +2

Query: 67  IRSVRLVRDKDTDKFKGFCYVEFDEVDSLKEAL-TYDGALLGDRSLRVD 114
           I + R+VRD  T K KG+ +V F +    + A+   +G  +G RS+R +
Sbjct: 110 ISNCRIVRDPQTMKSKGYAFVSFVKKAEAENAIQAMNGQWIGSRSIRTN 256
>11126
          Length = 1061

 Score = 35.4 bits (80), Expect = 0.020,   Method: Compositional matrix adjust.
 Identities = 23/73 (31%), Positives = 38/73 (52%), Gaps = 2/73 (2%)
 Frame = -3

Query: 43  TAYVGNLPFNTVQGDIDAIFKDL-SIRSVRLVRDKDTDKFKGFCYVEFDEVDSLKEA-LT 100
           + YVGN+ +     +++  F    S+  V ++ DK +   KGF YVEF + DS+  A  T
Sbjct: 627 SVYVGNVDYGATAEELEQHFHGCGSVNRVTILCDKYSGHPKGFAYVEFADKDSVVTAKCT 448

Query: 101 YDGALLGDRSLRV 113
              +L   R ++V
Sbjct: 447 GMDSLFRGRQIKV 409
>02343
          Length = 1715

 Score = 31.2 bits (69), Expect = 0.37,   Method: Compositional matrix adjust.
 Identities = 20/79 (25%), Positives = 42/79 (53%), Gaps = 1/79 (1%)
 Frame = -2

Query: 45   YVGNLPFNTVQGDIDAIFKDL-SIRSVRLVRDKDTDKFKGFCYVEFDEVDSLKEALTYDG 103
            Y+  L  NT   D+  + +   +I S + + D+ T+K KG+ +V+FD   + + A+    
Sbjct: 1255 YIRGLSPNTTDKDLVNLCQHFGTITSTKAIIDQTTNKCKGYGFVDFDAPGAAERAV---- 1088

Query: 104  ALLGDRSLRVDIAEGRKQD 122
              L  + ++  +A+ ++QD
Sbjct: 1087 QALQAQGIQAQMAKQQEQD 1031

 Score = 30.4 bits (67), Expect = 0.68,   Method: Compositional matrix adjust.
 Identities = 17/58 (29%), Positives = 32/58 (55%), Gaps = 3/58 (5%)
 Frame = -2

Query: 41   PYTAYVGNLPFNTVQGDIDAIFKDL-SIRSVRLVRDKD-TDKFKGFCYVEF-DEVDSL 95
            P   Y+ NLP +  +  ++ +FKD  ++ S R++R  D   +  GF  +E  D+ D++
Sbjct: 1030 PTNLYIANLPLHFTEKHLEGLFKDYGTVISTRILRKPDGISRCVGFARMESRDKCDTV 857
>39789
          Length = 361

 Score = 31.2 bits (69), Expect = 0.40,   Method: Compositional matrix adjust.
 Identities = 18/55 (32%), Positives = 29/55 (52%)
 Frame = +1

Query: 45  YVGNLPFNTVQGDIDAIFKDLSIRSVRLVRDKDTDKFKGFCYVEFDEVDSLKEAL 99
           +VGNL ++T Q  +   F   +  + R+ + +DT K +GF +VEF   D    A 
Sbjct: 97  FVGNLSYDTDQYSLKDAFPGAT--AARIAKFQDTQKPRGFGFVEFSTPDDAASAF 255
>30672
          Length = 877

 Score = 31.2 bits (69), Expect = 0.43,   Method: Compositional matrix adjust.
 Identities = 24/91 (26%), Positives = 45/91 (49%), Gaps = 8/91 (8%)
 Frame = +3

Query: 43  TAYVGNLPFNTVQGDIDAIFKDLS-IRSVRLVRDKDTDKFKGFCYVEFDEVD---SLKEA 98
           T +V NLPF T    +   F+ +  +++  +V  K+  K +GF YV+F  ++     K+ 
Sbjct: 15  TLFVRNLPFETSNEKLLEAFEQVGPLKTAFVVAGKEPGKCRGFGYVQFSMLEDAIKAKDT 194

Query: 99  LTYDGALLGDRSLRVDIAEGRK----QDKGG 125
           +T+       R + +  A+ +K    + KGG
Sbjct: 195 VTH----CSGRKISLSFADTKKSWKTKQKGG 275
>33504
          Length = 282

 Score = 30.8 bits (68), Expect = 0.54,   Method: Compositional matrix adjust.
 Identities = 13/34 (38%), Positives = 21/34 (61%), Gaps = 1/34 (2%)
 Frame = +1

Query: 44  AYVGNLPFNTVQGDIDAIFKDLS-IRSVRLVRDK 76
            ++G LP++  +GDI  +F     I ++ LVRDK
Sbjct: 175 VFIGGLPYDLTEGDIICVFSQYGEIVNINLVRDK 276
>01278
          Length = 1082

 Score = 30.8 bits (68), Expect = 0.54,   Method: Compositional matrix adjust.
 Identities = 20/71 (28%), Positives = 33/71 (46%), Gaps = 7/71 (9%)
 Frame = +2

Query: 43  TAYVGNLPFNTVQGDIDAIFKDLS-IRSVRLVRDKDTDKFKGFCYVEFDEVDSLKEALT- 100
           T  V NL  +T + D+  +F+    I  + L +DK T + KGF ++ F   +    A+  
Sbjct: 638 TIRVTNLSEDTRESDLQELFRPFGPISRIYLAKDKVTGQSKGFAFINFHRREDASRAIAG 817

Query: 101 -----YDGALL 106
                YD  +L
Sbjct: 818 VSGFGYDHLIL 850
>12506
          Length = 1056

 Score = 30.4 bits (67), Expect = 0.71,   Method: Compositional matrix adjust.
 Identities = 17/61 (27%), Positives = 35/61 (57%), Gaps = 2/61 (3%)
 Frame = -3

Query: 67  IRSVRLVRDKDTDKFKGFCYVEFDEVDSLKEAL--TYDGALLGDRSLRVDIAEGRKQDKG 124
           I  +++  D +T+K +GF ++EF+  +    A+    +  L G R++RV++A+  K  +G
Sbjct: 985 IVDIQIPLDYETEKHRGFAFIEFELAEDAAAAIDNMNESELFG-RTIRVNLAKPMKVKEG 809

Query: 125 G 125
            
Sbjct: 808 A 806
>00556
          Length = 2189

 Score = 30.0 bits (66), Expect = 0.83,   Method: Compositional matrix adjust.
 Identities = 20/74 (27%), Positives = 34/74 (45%), Gaps = 2/74 (2%)
 Frame = +3

Query: 42  YTAYVGNLPFNTVQGDIDAIFKDLS-IRSVRLVRDKDTDKFKGFCYVEFDEVDSLKEALT 100
           +  ++G LP    +  +  +      ++S  LVRD  T   KGF + E+ +     +A  
Sbjct: 759 HKIFMGGLPSYLSEDQMKELLLSFGPLKSFNLVRDNATGLSKGFAFCEYLDPSVTDQACA 938

Query: 101 -YDGALLGDRSLRV 113
             +G  LGD+ L V
Sbjct: 939 GLNGMQLGDKKLIV 980
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|170671704|ref|NP_083546.2| Rho GTPase activating
protein 24 isoform 1 [Mus musculus]
         (747 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

17558                                                                  92   8e-19
12558                                                                  89   9e-18
17428                                                                  85   1e-16
20879                                                                  65   7e-15
13952                                                                  61   1e-09
30765                                                                  58   1e-08
11945                                                                  49   7e-06
29521                                                                  43   6e-04
15376                                                                  41   0.002
27925                                                                  40   0.003
19079                                                                  38   0.013
21189                                                                  37   0.038
13073                                                                  36   0.055
29522                                                                  34   0.17 
19361                                                                  33   0.32 
18916                                                                  31   1.9  
13698                                                                  31   1.9  
05879                                                                  30   2.7  
28896                                                                  30   3.4  
19246                                                                  29   5.7  
11228                                                                  29   8.7  
>17558
          Length = 671

 Score = 92.0 bits (227), Expect = 8e-19,   Method: Composition-based stats.
 Identities = 56/207 (27%), Positives = 106/207 (51%), Gaps = 6/207 (2%)
 Frame = +3

Query: 130 IFGQKLEDTVRYEKRYGNRLAPMLVEQCVDFIRQRGLKEEGLFRLPGQANLVKELQDAFD 189
           +FG  LE+   Y +  G  + P++++ C+  I   GL  +G+FR+ G    +   ++ F+
Sbjct: 54  LFGGSLEE---YIEATGEEI-PLIIKGCIRVINLYGLHHQGVFRVSGAQVEINHFKNVFE 221

Query: 190 CGEKPSFD--SNTDVHTVASLLKLYLRELPEPVVPYAKYEDFLSCATLLSKEEEAGVKEL 247
            G+    D    +D++++A +LKLY REL EP+ P   ++  + C        E  V   
Sbjct: 222 SGDDALVDVVDASDMNSIAGVLKLYFRELREPLFPLHLFDALVECT------RENDVHRR 383

Query: 248 MKQVK----SLPVVNYNLLKYICRFLDEVQSYSGVNKMSAQNLATVFGPNILRPKVEDPL 303
           ++++K    +LP   + +++Y+  FL+ +  YS  N M   NLA  FGP +L    +   
Sbjct: 384 LERIKDLLATLPRSVFVVMRYLFAFLNHLSEYSDENMMDPYNLAICFGPTLLPIPPDRDQ 563

Query: 304 TIMEGTVVVQQLMSVMISKHDRLFPKD 330
            ++ G  + Q+++  +I   + +FP D
Sbjct: 564 VVLPG--LRQRIIKTIIVHQEEIFPND 638
>12558
          Length = 720

 Score = 88.6 bits (218), Expect = 9e-18,   Method: Compositional matrix adjust.
 Identities = 49/134 (36%), Positives = 76/134 (56%), Gaps = 4/134 (2%)
 Frame = -1

Query: 169 EGLFRLPGQANLVKELQDAFDCGEKPSFDSNT----DVHTVASLLKLYLRELPEPVVPYA 224
           +GL+RL G  + +++L+ AFD  + P    N     D+H+++SLLK+Y RELP P++ Y 
Sbjct: 714 DGLYRLSGVTSNIQKLRVAFDEDQAPELSDNVQYLQDIHSISSLLKMYFRELPNPLLTYQ 535

Query: 225 KYEDFLSCATLLSKEEEAGVKELMKQVKSLPVVNYNLLKYICRFLDEVQSYSGVNKMSAQ 284
            Y  F        K+E+  +  +   V+ LP  +Y  L+Y+ R L  V SY     M ++
Sbjct: 534 LYTQFADAV----KDEDNRLLRIHDVVQQLPPPHYRTLEYLVRHLACVASYGLQTGMHSK 367

Query: 285 NLATVFGPNILRPK 298
           NLA V+ PN+LR K
Sbjct: 366 NLAIVWAPNLLRSK 325
>17428
          Length = 623

 Score = 84.7 bits (208), Expect = 1e-16,   Method: Compositional matrix adjust.
 Identities = 54/165 (32%), Positives = 85/165 (51%)
 Frame = +1

Query: 169 EGLFRLPGQANLVKELQDAFDCGEKPSFDSNTDVHTVASLLKLYLRELPEPVVPYAKYED 228
           EGLFR    +   ++L+  FD       + + D +TVA ++K YLRELPEP++ +  Y D
Sbjct: 1   EGLFRFSRISFKDEKLKACFDARLVDMEEFSNDPNTVAGVMKQYLRELPEPMLTFDLYPD 180

Query: 229 FLSCATLLSKEEEAGVKELMKQVKSLPVVNYNLLKYICRFLDEVQSYSGVNKMSAQNLAT 288
           F+  A L     +   + L   V  LP  N+N  +Y+ +FL  +   S VNKM+  NLA 
Sbjct: 181 FMRAAQL---GHDQKCQSLYTLVNRLPPSNFNNFRYLIKFLALLAEKSHVNKMTPSNLAI 351

Query: 289 VFGPNILRPKVEDPLTIMEGTVVVQQLMSVMISKHDRLFPKDTEP 333
           V GPN+L  + E+   +M  +  V  ++   +   +  FP +  P
Sbjct: 352 VMGPNLLWARGENTPNMMTAS-TVSSIIETFVLHAEYFFPGELXP 483
>20879
          Length = 1019

 Score = 64.7 bits (156), Expect(2) = 7e-15,   Method: Compositional matrix adjust.
 Identities = 31/78 (39%), Positives = 48/78 (61%)
 Frame = -2

Query: 149 LAPMLVEQCVDFIRQRGLKEEGLFRLPGQANLVKELQDAFDCGEKPSFDSNTDVHTVASL 208
           + P LV  C + I +RGL E G++R+PG     K+L++ F  G+ P+  +  D+HTV   
Sbjct: 568 MIPRLVVNCANEIERRGLSEVGIYRVPGSDRDSKDLKEKFLKGKSPNLSNIIDIHTVCGC 389

Query: 209 LKLYLRELPEPVVPYAKY 226
           LK +LR L EP+V +A +
Sbjct: 388 LKDFLRNLKEPLVTFALW 335

 Score = 34.3 bits (77), Expect(2) = 7e-15,   Method: Compositional matrix adjust.
 Identities = 19/56 (33%), Positives = 30/56 (53%)
 Frame = -1

Query: 247 LMKQVKSLPVVNYNLLKYICRFLDEVQSYSGVNKMSAQNLATVFGPNILRPKVEDP 302
           + + + +LP  N + L ++ + L +V S S   KM A NLA VFGP  +     +P
Sbjct: 281 VCEAINNLPTANRDTLAFLVQHLQKV-SESTATKMPASNLAKVFGPTAVGYSCPEP 117
>13952
          Length = 577

 Score = 61.2 bits (147), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 37/114 (32%), Positives = 51/114 (44%), Gaps = 10/114 (8%)
 Frame = -3

Query: 19  TKCGWLRKQGGFVKTWHTRWFVLKGDQLYYFKDEDETKPLGTIFLHGNKVIEHPCNEENP 78
            K GWL KQGG  K W  RWF+L  + LYYF+   + +P G I L   +V E        
Sbjct: 419 VKEGWLMKQGGRYKNWKRRWFILNDNCLYYFQYTADKEPKGIIPLENIQVRELSEKSSRS 240

Query: 79  GKFLFEVVPGGERDR----------MTANHESYLLMASTQNDMEDWVKSIRRVI 122
             F    V G +  +          +   H  Y + AS+  +M+ W+ SIR  I
Sbjct: 239 NAFELYSVSGSDVIKACKVDSDGKVVEGRHSVYRMSASSAEEMDAWISSIRYGI 78
>30765
          Length = 635

 Score = 58.2 bits (139), Expect = 1e-08,   Method: Composition-based stats.
 Identities = 38/147 (25%), Positives = 67/147 (45%), Gaps = 1/147 (0%)
 Frame = +2

Query: 88  GGERDRMTANHESYLLMASTQNDMEDWVKSIRRVIWGPFGGGIFGQKLEDTVRYEKRYGN 147
           G ER RM       L     +   ED +K       G     +FG  L+     +K    
Sbjct: 167 GAERVRMAGIKSKLLSFLIRRPTQEDLIKQ------GIIKDAVFGSTLQAQCDKDKA--- 319

Query: 148 RLAPMLVEQCVDFIRQRGLKEEGLFRLPGQANLVKELQDAFDCGEKPSFDSNT-DVHTVA 206
              P  V +C+  + ++GL ++GL+R+ G    ++ L+   D  +  +   +  D+HT+ 
Sbjct: 320 -PVPNFVLECIAAVEKKGLDQDGLYRVSGNLAEIQRLRYVVDKDDDHNLTEDQWDIHTLT 496

Query: 207 SLLKLYLRELPEPVVPYAKYEDFLSCA 233
             LKL+ REL EP+ P+   + F++ +
Sbjct: 497 GALKLFFRELKEPLFPWKCIDKFINAS 577
>11945
          Length = 1161

 Score = 48.9 bits (115), Expect = 7e-06,   Method: Compositional matrix adjust.
 Identities = 39/130 (30%), Positives = 57/130 (43%), Gaps = 9/130 (6%)
 Frame = -1

Query: 171 LFRLPGQANLVKEL---------QDAFDCGEKPSFDSNTDVHTVASLLKLYLRELPEPVV 221
             R+PG    VK+L         Q+ F+ GE    D        A+LLK +LRELP P++
Sbjct: 423 FLRVPGSVTRVKQLRHELEEKFYQNTFNWGEVMPNDC-------AALLKQFLRELPTPLL 265

Query: 222 PYAKYEDFLSCATLLSKEEEAGVKELMKQVKSLPVVNYNLLKYICRFLDEVQSYSGVNKM 281
            Y   E F     +    E+         V  LP  + ++LK + RFL  + S+S  NKM
Sbjct: 264 TYDYLEAFPQVENIPKTLEQLKALN--LLVLLLPTEHRDVLKVLLRFLRNIVSHSDTNKM 91

Query: 282 SAQNLATVFG 291
              N+  +  
Sbjct: 90  GLNNICMIMA 61
>29521
          Length = 903

 Score = 42.7 bits (99), Expect = 6e-04,   Method: Compositional matrix adjust.
 Identities = 25/83 (30%), Positives = 42/83 (50%), Gaps = 1/83 (1%)
 Frame = +1

Query: 37  RWFVLKGDQ-LYYFKDEDETKPLGTIFLHGNKVIEHPCNEENPGKFLFEVVPGGERDRMT 95
           R+F+L+ D  LYY+K  +++ PLG I L G     H    ++   F F+    G R    
Sbjct: 1   RYFILRQDSCLYYYKQREDSDPLGAIPLAGYTFSRHL---DSGRDFCFKAEKYGAR---- 159

Query: 96  ANHESYLLMASTQNDMEDWVKSI 118
               +Y  M  +++DM +WV ++
Sbjct: 160 ----TYYFMTESRDDMTEWVGAL 216

 Score = 37.4 bits (85), Expect = 0.023,   Method: Compositional matrix adjust.
 Identities = 18/49 (36%), Positives = 27/49 (55%)
 Frame = +3

Query: 11  PQGQGRQNTKCGWLRKQGGFVKTWHTRWFVLKGDQLYYFKDEDETKPLG 59
           P  + R+    G+L K G   +TWH R+ +LK   LYY+K+ +    LG
Sbjct: 288 PALEVRRPECTGYLLKVGNRRRTWHRRYCILKDACLYYYKNMNSLSALG 434
>15376
          Length = 712

 Score = 40.8 bits (94), Expect = 0.002,   Method: Composition-based stats.
 Identities = 27/96 (28%), Positives = 41/96 (42%), Gaps = 10/96 (10%)
 Frame = +1

Query: 37  RWFVLKGDQLYYFKDEDETKPLGTIFLHGNKVIEHPCNEENPGKFLFEVVPGGERDR--- 93
           RWF+L  + LYYF+   + +P G I L   +V E          F    V G +  +   
Sbjct: 1   RWFILNDNCLYYFQYTADKEPKGIIPLENIQVRELSEKSSRSNAFELYSVSGSDVIKACK 180

Query: 94  -------MTANHESYLLMASTQNDMEDWVKSIRRVI 122
                  +   H  Y + AS+  +M+ W+ SIR  I
Sbjct: 181 VDSDGKVVEGRHSVYRMSASSAEEMDAWISSIRSSI 288
>27925
          Length = 370

 Score = 40.4 bits (93), Expect = 0.003,   Method: Composition-based stats.
 Identities = 20/54 (37%), Positives = 30/54 (55%), Gaps = 1/54 (1%)
 Frame = +3

Query: 32 KTWHTRWFVLKGDQ-LYYFKDEDETKPLGTIFLHGNKVIEHPCNEENPGKFLFE 84
          K W  RWF L+ D  LYY+K ED+++P+G + +  + V   P +   P  F  E
Sbjct: 21 KKWVRRWFSLRPDNCLYYYKTEDDSQPVGAMIMAKHTVELCPIDIGKPFGFKVE 182
>19079
          Length = 436

 Score = 38.1 bits (87), Expect = 0.013,   Method: Composition-based stats.
 Identities = 24/92 (26%), Positives = 49/92 (53%), Gaps = 3/92 (3%)
 Frame = -1

Query: 176 GQANLVKELQDAFDCGEKPSFDSN--TDVHTVASLLKLYLRELPEPVVPYAKYEDFLSCA 233
           GQ + +   +  F+ GE    D    +++++VA +LKLY REL EP+ P   ++  + C 
Sbjct: 382 GQVD-INNFKAVFESGEDALVDVTDASEMNSVAGVLKLYFRELREPLFPLHLFDALVECT 206

Query: 234 TLLSKEEEA-GVKELMKQVKSLPVVNYNLLKY 264
             +S +     +++L+    SLP   + ++++
Sbjct: 205 REISVQRRLDSIRDLL---ASLPRAIFVVMRW 119
>21189
          Length = 461

 Score = 36.6 bits (83), Expect = 0.038,   Method: Compositional matrix adjust.
 Identities = 28/91 (30%), Positives = 41/91 (45%), Gaps = 1/91 (1%)
 Frame = +3

Query: 132 GQKLEDTVRYEKRYGNRLAPMLVEQCVDFIRQRGLKEEGLFRLPGQANLVKELQDAFD-C 190
           GQ L   V Y  RY               +R+      G+FR  G  + + +L+D  + C
Sbjct: 213 GQPLPQCVLYAMRY---------------LRKTSHDAVGIFRKSGVRSRIHKLRDMVESC 347

Query: 191 GEKPSFDSNTDVHTVASLLKLYLRELPEPVV 221
            +  +FD     + VA LLK Y RELPE ++
Sbjct: 348 PDTVNFD-ELQPYDVADLLKQYFRELPECLL 437
>13073
          Length = 490

 Score = 36.2 bits (82), Expect = 0.055,   Method: Composition-based stats.
 Identities = 28/99 (28%), Positives = 41/99 (41%), Gaps = 2/99 (2%)
 Frame = -2

Query: 22  GWLRKQGGFVKTWHTRWFVLKGDQLYYFKDEDETK--PLGTIFLHGNKVIEHPCNEENPG 79
           G L K   ++  W  R+ VLK   L Y+K EDET     G + L    V  H  +E    
Sbjct: 264 GTLSKWTNYLHGWQDRYIVLKDGTLSYYKSEDETAFGCRGAVSLTRATVTPHQFDE---- 97

Query: 80  KFLFEVVPGGERDRMTANHESYLLMASTQNDMEDWVKSI 118
                      R  ++ N   + L +ST  + + WV S+
Sbjct: 96  ----------CRFDVSVNDSVWYLRSSTLEERQRWVDSV 10
>29522
          Length = 698

 Score = 34.3 bits (77), Expect = 0.17,   Method: Compositional matrix adjust.
 Identities = 21/63 (33%), Positives = 31/63 (49%), Gaps = 2/63 (3%)
 Frame = -3

Query: 2   EERCESTESPQGQGRQNTKCGWLRKQG-GFVKTWHT-RWFVLKGDQLYYFKDEDETKPLG 59
           +++ ES  S +  G Q  + GWL      F+K      WFVL  + L +FKDE+ +  L 
Sbjct: 228 QQKAESQSSKRKMGNQVIRKGWLSLHNISFIKGGSKDFWFVLTAESLSWFKDEEVSFLLS 49

Query: 60  TIF 62
             F
Sbjct: 48  VAF 40
>19361
          Length = 685

 Score = 33.5 bits (75), Expect = 0.32,   Method: Compositional matrix adjust.
 Identities = 12/27 (44%), Positives = 21/27 (77%)
 Frame = -1

Query: 148 RLAPMLVEQCVDFIRQRGLKEEGLFRL 174
           ++ P++VE C+  I +RG++ EGL+RL
Sbjct: 97  QILPIVVEXCIKEIEKRGVEPEGLYRL 17
>18916
          Length = 574

 Score = 30.8 bits (68), Expect = 1.9,   Method: Compositional matrix adjust.
 Identities = 15/34 (44%), Positives = 19/34 (55%)
 Frame = -3

Query: 22  GWLRKQGGFVKTWHTRWFVLKGDQLYYFKDEDET 55
           G L K   ++  W  R+ VLK   L Y+K EDET
Sbjct: 404 GTLSKWTNYLHGWQDRYIVLKDGTLSYYKSEDET 303
>13698
          Length = 951

 Score = 30.8 bits (68), Expect = 1.9,   Method: Compositional matrix adjust.
 Identities = 16/33 (48%), Positives = 22/33 (66%)
 Frame = +1

Query: 223 YAKYEDFLSCATLLSKEEEAGVKELMKQVKSLP 255
           +AK  DF++ AT L +  E  VKE MK+VK +P
Sbjct: 241 HAKLNDFVAAATKLGEGRE*NVKEQMKRVKLVP 339
>05879
          Length = 713

 Score = 30.4 bits (67), Expect = 2.7,   Method: Compositional matrix adjust.
 Identities = 14/34 (41%), Positives = 19/34 (55%), Gaps = 3/34 (8%)
 Frame = +2

Query: 33  TWHTRWFVLKGDQLYYFK---DEDETKPLGTIFL 63
           +WH RW  L  ++L Y+K   DE    P+G I L
Sbjct: 206 SWHRRWCALSSNKLQYWKYPDDETRKDPMGYIDL 307
>28896
          Length = 415

 Score = 30.0 bits (66), Expect = 3.4,   Method: Composition-based stats.
 Identities = 16/43 (37%), Positives = 20/43 (46%)
 Frame = +3

Query: 285 NLATVFGPNILRPKVEDPLTIMEGTVVVQQLMSVMISKHDRLF 327
           NLA V  PN LR + +DP  I E T      +  +I   D  F
Sbjct: 9   NLAMVMAPNCLRCESQDPRIIFENTRKEMGFLRTLIQSLDTSF 137
>19246
          Length = 440

 Score = 29.3 bits (64), Expect = 5.7,   Method: Compositional matrix adjust.
 Identities = 23/94 (24%), Positives = 37/94 (39%), Gaps = 6/94 (6%)
 Frame = +2

Query: 32  KTWHTRWFVLKGDQLYYFKDEDETKPLGTIFLHGNKVIEHPCNEENPGKFLFEVVPGGER 91
           ++W   W VL+G  L+  KD  +     T       +    C        L ++     R
Sbjct: 62  RSWKQVWAVLRGHALFLIKDRRDGSTHPTFSFEEPPISIKSC--------LVDIAHDYSR 217

Query: 92  D-----RMTANHES-YLLMASTQNDMEDWVKSIR 119
                 R+T   ES YLL A  +  M  W+++I+
Sbjct: 218 KRKHVFRLTTYSESVYLLQAEDKGTMMSWIQAIK 319
>11228
          Length = 2155

 Score = 28.9 bits (63), Expect = 8.7,   Method: Compositional matrix adjust.
 Identities = 15/44 (34%), Positives = 26/44 (59%), Gaps = 2/44 (4%)
 Frame = -2

Query: 22   GWLRKQGGFVKTWHTRWFVLKG--DQLYYFKDEDETKPLGTIFL 63
            G+L  +   +K +   +FVL G  + LY+F++E  +KP G + L
Sbjct: 1056 GYLHYRNEKMKKFKPYYFVLNGTENMLYFFENEKRSKPKGLVEL 925
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|30840992|ref|NP_083916.1| trafficking protein
particle complex 9 isoform 1 [Mus musculus]
         (960 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

29230                                                                  92   8e-19
25006                                                                  31   2.0  
20627                                                                  30   5.6  
>29230
          Length = 766

 Score = 92.4 bits (228), Expect = 8e-19,   Method: Compositional matrix adjust.
 Identities = 36/61 (59%), Positives = 52/61 (85%)
 Frame = +1

Query: 7   RHYKKRCQGRMRKHVGDLCLQAGMLQDALVHYHMSVELLRSVNDFLWLGAALEGLCSASV 66
           + +K++C GR+RKH+GDLCLQA +  +A++HY  +++LLR+VNDFLW+GA  EGLCSASV
Sbjct: 451 KSFKRKCMGRLRKHLGDLCLQASLPGEAILHYQTALDLLRTVNDFLWMGACYEGLCSASV 630

Query: 67  I 67
           +
Sbjct: 631 V 633
>25006
          Length = 803

 Score = 31.2 bits (69), Expect = 2.0,   Method: Composition-based stats.
 Identities = 20/66 (30%), Positives = 33/66 (50%), Gaps = 3/66 (4%)
 Frame = -2

Query: 331 EPITLPDGLTLPPVPFTKLPIVRCVKLLSLPTSLRPHKVKSLLGQSMSTKSP---FIYSP 387
           +P+ + +  T+    FTK PI+   K L L    + H  K++  Q  ST S    F +SP
Sbjct: 748 KPLQVRNCDTIQCFAFTKCPIIYTSKRLWLAALRQKHHSKNVYSQPGSTSSTSTIFFFSP 569

Query: 388 IIAHNR 393
             +H++
Sbjct: 568 YSSHHQ 551
>20627
          Length = 566

 Score = 29.6 bits (65), Expect = 5.6,   Method: Compositional matrix adjust.
 Identities = 19/58 (32%), Positives = 28/58 (48%)
 Frame = +2

Query: 611 SCQENLLQDLSDDGISVSGFPLSSPFRQVVRPRVESRPTNPSEGSKTGDLGHVKTLEA 668
           +CQE+ + D S +G     +  S P   V+RP V  R T+ + GSK     H  T + 
Sbjct: 242 TCQEHSVPDASHNGA----Y*RSHPVYVVIRPVVGGRKTDGNGGSKATSRVHGSTCDG 403
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|7242142|ref|NP_036133.1| COP9 (constitutive
photomorphogenic) homolog, subunit 7a [Mus musculus]
         (275 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

00822                                                                  90   8e-19
33779                                                                  29   2.4  
02347                                                                  28   3.3  
02735                                                                  28   3.3  
>00822
          Length = 1294

 Score = 90.1 bits (222), Expect = 8e-19,   Method: Compositional matrix adjust.
 Identities = 52/124 (41%), Positives = 72/124 (58%), Gaps = 2/124 (1%)
 Frame = +2

Query: 150 QRLEVDYSIGRDIQRQDLSAIAQTLQEWCVGCEVVLSGIEEQVSRANQHKEQQLGLKQQI 209
           Q+LEVDY IGRDI+   ++ +   L EWC GC+ VL GIE Q+S+AN ++E QL     +
Sbjct: 2   QQLEVDYVIGRDIRPTAINQMMTVLSEWCKGCDAVLLGIETQISKANHNRESQLRTVANM 181

Query: 210 ESEVANLKKTIKVXXXXXXXXXSQDPEQHLTELREPASGTNQRQPSKKASKGKGLRG--S 267
           E E+  +KK IKV          +  EQ +T++       +     KK S+GKGLRG  S
Sbjct: 182 EQEITAIKKNIKV------TLGQEGEEQMVTDM-------DHHDKPKKPSRGKGLRGSTS 322

Query: 268 AKIW 271
           AK+W
Sbjct: 323 AKLW 334
>33779
          Length = 360

 Score = 28.9 bits (63), Expect = 2.4,   Method: Compositional matrix adjust.
 Identities = 18/52 (34%), Positives = 27/52 (51%)
 Frame = +1

Query: 73  GTYADYLAEARNLPPLTDAQKNKLRHLSVVTLAAKVKCIPYAVLLEALALRN 124
           GT   +  +A NLP     Q+NKL   +V T   K+K IP+   +  + +RN
Sbjct: 94  GTNHSFF-KAYNLP--IGKQQNKLTTTTVYTSGEKLKTIPFLKNIHVIIMRN 240
>02347
          Length = 928

 Score = 28.5 bits (62), Expect = 3.3,   Method: Compositional matrix adjust.
 Identities = 14/32 (43%), Positives = 20/32 (62%), Gaps = 4/32 (12%)
 Frame = +1

Query: 74  TYADYLAEARNLPPLTDAQKNKLR----HLSV 101
           T +D   EAR L P+T A K+++R    HLS+
Sbjct: 106 TMSDVFTEARRLKPVTQAMKDQVRDEQSHLSL 201
>02735
          Length = 970

 Score = 28.5 bits (62), Expect = 3.3,   Method: Compositional matrix adjust.
 Identities = 14/32 (43%), Positives = 20/32 (62%), Gaps = 4/32 (12%)
 Frame = +2

Query: 74  TYADYLAEARNLPPLTDAQKNKLR----HLSV 101
           T +D   EAR L P+T A K+++R    HLS+
Sbjct: 104 TMSDVFTEARRLKPVTQAMKDQVRDEQSHLSL 199
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|165377150|ref|NP_001004357.2| contactin associated
protein-like 2 isoform a [Mus musculus]
         (1332 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

29854                                                                  92   9e-19
18680                                                                  75   2e-13
06395                                                                  44   4e-04
13401                                                                  40   0.009
05519                                                                  35   0.15 
00070                                                                  34   0.46 
08472                                                                  33   1.1  
13645                                                                  33   1.1  
12576                                                                  33   1.1  
13514                                                                  32   1.8  
32228                                                                  31   3.1  
14158                                                                  30   7.5  
>29854
          Length = 417

 Score = 92.4 bits (228), Expect = 9e-19,   Method: Compositional matrix adjust.
 Identities = 50/133 (37%), Positives = 73/133 (54%), Gaps = 4/133 (3%)
 Frame = -1

Query: 568 KCSQTWDSFKCTCDETGYSGATCHNSIYEPSCEAYKHLG--QTSNYYWIDPDGSGPLGPL 625
           KC+Q+W++F C C  TGY G  CH S +  SCE +K     + +    IDPDGSGPL P 
Sbjct: 417 KCTQSWNTFDCDCQNTGYKGEMCHISAHHISCEMHKQYSNIEGAELAVIDPDGSGPLPPF 238

Query: 626 KVYCNMTEDK-VWTIVSHDLQMQTTVVGYNPEKYSVTQLIY-SASMDQISAITSSAEYCE 683
           +V C+   D+ + T + HD Q    V G++     V ++ Y + +M  +  I   A+ C 
Sbjct: 237 EVTCDRDADRTIMTSIGHDSQDYILVNGFSEPGSYVRKIHYVTDNMLALEDIIERADTCR 58

Query: 684 QYVSYFCRMSRLL 696
           QY+ Y C  S+LL
Sbjct: 57  QYIDYRCNNSKLL 19

 Score = 30.4 bits (67), Expect = 5.1,   Method: Compositional matrix adjust.
 Identities = 10/24 (41%), Positives = 15/24 (62%)
 Frame = -1

Query: 979  KCIEKYHGYSCDCSNTAYDGTFCN 1002
            KC + ++ + CDC NT Y G  C+
Sbjct: 417  KCTQSWNTFDCDCQNTGYKGEMCH 346
>18680
          Length = 451

 Score = 75.1 bits (183), Expect = 2e-13,   Method: Compositional matrix adjust.
 Identities = 52/165 (31%), Positives = 81/165 (49%), Gaps = 6/165 (3%)
 Frame = -3

Query: 974  CENGGKCIEKYHGYSCDCSNTAYDGTFCNKDVGAFFEEGMWLRYNFQAPAVTARDTGSRA 1033
            C NGG C E Y  Y+CDCS T + G  C ++VG   ++   ++Y F              
Sbjct: 431  CFNGGTCREGYSRYTCDCSYTPWRGWNCGREVGVNLKQNYMIQYEF-------------- 294

Query: 1034 ENSADQQQHLAPDLAQEQIHFSFSTTKAPCILLYVSSLTT-DFLAVLVKPTGNLQIRYNL 1092
                +QQ   A D     I FS    +   IL+ + S+TT D+++V +   G +++ +++
Sbjct: 293  ---TEQQGLSATDFQYATIGFSTKVKQG--ILMQMKSVTTSDYISVEMNNNGGVKVVFDV 129

Query: 1093 GGTREPFN---IDVDHRNMANGQPHSVNITRHE--RTIILKLDHY 1132
            G  RE  N   IDVD    AN Q H V I R    R +++++D+Y
Sbjct: 128  GFQREEVNTPEIDVD---FANTQVHVVTIRRSNKGRRVVVQVDNY 3

 Score = 30.8 bits (68), Expect = 4.3,   Method: Compositional matrix adjust.
 Identities = 11/38 (28%), Positives = 18/38 (47%)
 Frame = -3

Query: 557 RCVPNHCEHGGKCSQTWDSFKCTCDETGYSGATCHNSI 594
           +C  N C +GG C + +  + C C  T + G  C   +
Sbjct: 449 KCASNPCFNGGTCREGYSRYTCDCSYTPWRGWNCGREV 336
>06395
          Length = 914

 Score = 43.9 bits (102), Expect = 4e-04,   Method: Composition-based stats.
 Identities = 43/166 (25%), Positives = 70/166 (42%), Gaps = 6/166 (3%)
 Frame = -2

Query: 187 VINFDGHGVLPYRFR----NKKMKTLKDVIALKFKTSESEGVL-LHGEGQQGDYITLELK 241
           +I  DG   + + F     +  ++T ++  +  F T++ EG++  H E ++  Y  L +K
Sbjct: 658 IIRLDGSSYVKFDFSRLPPDTLVRTQEEEFSFYFLTNKPEGLIWYHEEPRRNLY--LAMK 485

Query: 242 KAKLVLSLNLGSNQLGPIYGHTSVTSGSLLDDHHWHSVLIERQGRSINLTLDRSMQHFRT 301
              LV   +  S    P        SG   DD+ WH + I R GR I LT+D        
Sbjct: 484 DGHLVFVNDDKSGT--PEQVIIGERSGKRFDDYRWHKLKIRRNGRRIRLTVDDKYPQDYI 311

Query: 302 NGEFDYLDLDYEITFGGIPFS-GKPSSSNRKNFKGCMESINYNGVN 346
             E        ++  GGI  + G+   + R NF G +  + Y   N
Sbjct: 310 FSEDVQFITPAQVWLGGILDTLGRTKGNIRNNFDGGVAEVIYVSTN 173
>13401
          Length = 497

 Score = 39.7 bits (91), Expect = 0.009,   Method: Compositional matrix adjust.
 Identities = 18/36 (50%), Positives = 24/36 (66%)
 Frame = -3

Query: 555 IDRCVPNHCEHGGKCSQTWDSFKCTCDETGYSGATC 590
            D C  + C++GG CSQ  + F+CTC +TGY G TC
Sbjct: 108 TDECASSPCKNGGNCSQGNNKFQCTCTDTGYRGDTC 1

 Score = 33.9 bits (76), Expect = 0.47,   Method: Compositional matrix adjust.
 Identities = 14/32 (43%), Positives = 19/32 (59%)
 Frame = -3

Query: 974  CENGGKCIEKYHGYSCDCSNTAYDGTFCNKDV 1005
            CENG  C++    Y C+C+ T Y+G FC  D 
Sbjct: 201  CENGAPCVDGIRQYFCNCTGTGYEGEFCQTDT 106
>05519
          Length = 1164

 Score = 35.4 bits (80), Expect = 0.15,   Method: Compositional matrix adjust.
 Identities = 20/47 (42%), Positives = 26/47 (55%), Gaps = 5/47 (10%)
 Frame = -2

Query: 553 AIIDRCVPNHCEHGGKCS-----QTWDSFKCTCDETGYSGATCHNSI 594
           +I D C  + C++G KCS          FKCTC + GYSG TC  S+
Sbjct: 317 SIPDVCASSPCKNGAKCSVQVTRARLSLFKCTCAK-GYSGETCDQSV 180
>00070
          Length = 1809

 Score = 33.9 bits (76), Expect = 0.46,   Method: Compositional matrix adjust.
 Identities = 20/47 (42%), Positives = 26/47 (55%), Gaps = 5/47 (10%)
 Frame = +1

Query: 553 AIIDRCVPNHCEHGGKCS-----QTWDSFKCTCDETGYSGATCHNSI 594
           +I D C  + C++G KCS          FKCTC + GYSG TC  S+
Sbjct: 130 SIPDVCASSPCKNGAKCSVQVTRARLSLFKCTCAK-GYSGETCDQSV 267
>08472
          Length = 537

 Score = 32.7 bits (73), Expect = 1.1,   Method: Composition-based stats.
 Identities = 32/131 (24%), Positives = 53/131 (40%), Gaps = 2/131 (1%)
 Frame = +3

Query: 349 DLARRKKLEPSNMGNLSFSCVEPYTVPVF--FNATSYLEVPGRLNQDLFSVSFQFRTWNP 406
           ++A  K   PS  GN S+  + P  +P+       S    P    ++   +S  F T  P
Sbjct: 15  EIALSKPTTPSFRGN-SYLILPPPRIPMKDKRRGPSLYVRP----REAIQISLNFSTIEP 179

Query: 407 SGLLLFSHFADNLGNVEIDLVESKVGVHINNTQTKTSQIDISSGSGLNDGQWHEVRFLAK 466
            GLLL+S   + L  + + L    + +  N   +    +   +   + DG WH    L  
Sbjct: 180 DGLLLWSQH-NQLKFLGLGLENGHLKLASNLLGSNNDTVQAPASGFIADGAWHGTSVLLD 356

Query: 467 ENFAVLTIDGD 477
            N   L +DG+
Sbjct: 357 RNRLELQLDGE 389
>13645
          Length = 2160

 Score = 32.7 bits (73), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 16/55 (29%), Positives = 28/55 (50%), Gaps = 1/55 (1%)
 Frame = +1

Query: 587 GATC-HNSIYEPSCEAYKHLGQTSNYYWIDPDGSGPLGPLKVYCNMTEDKVWTIV 640
           G TC H ++ +P+         ++  YWIDP+G      ++V+C M  +K  T +
Sbjct: 442 GRTCRHIALADPTV--------SNGMYWIDPNGGSSHDAIRVFCKMNAEKTMTCL 582
>12576
          Length = 1682

 Score = 32.7 bits (73), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 16/39 (41%), Positives = 21/39 (53%)
 Frame = -2

Query: 552  CAIIDRCVPNHCEHGGKCSQTWDSFKCTCDETGYSGATC 590
            C  I  C  N C++GG+C     SF C+C   G+SG  C
Sbjct: 1678 CTPITACDSNPCQNGGQCQPNGGSFTCSCVN-GFSGVNC 1565

 Score = 31.6 bits (70), Expect = 2.2,   Method: Compositional matrix adjust.
 Identities = 17/38 (44%), Positives = 24/38 (63%)
 Frame = -1

Query: 560  PNHCEHGGKCSQTWDSFKCTCDETGYSGATCHNSIYEP 597
            PN C +GG+C++   SF C C   GY+G TC  S+ +P
Sbjct: 1427 PNPCRNGGRCNRNGASFSCVC-VGGYNGLTCA-SLSDP 1320

 Score = 31.2 bits (69), Expect = 2.8,   Method: Compositional matrix adjust.
 Identities = 19/41 (46%), Positives = 23/41 (56%), Gaps = 4/41 (9%)
 Frame = -1

Query: 554  IIDRCVPNHCEHGGKCSQTWD----SFKCTCDETGYSGATC 590
            + D C PN C++GG CS T      +FKC C   GY G TC
Sbjct: 1205 LADPCKPNPCKNGGLCSTTVVGGALTFKCFC-SAGYDGKTC 1086
>13514
          Length = 1135

 Score = 32.0 bits (71), Expect = 1.8,   Method: Compositional matrix adjust.
 Identities = 16/34 (47%), Positives = 21/34 (61%)
 Frame = -2

Query: 563 CEHGGKCSQTWDSFKCTCDETGYSGATCHNSIYE 596
           CEHGG C     S++C C  TG++G  C N+I E
Sbjct: 567 CEHGGTCQNLNGSYQCNC-PTGFTGRRCENNINE 469
>32228
          Length = 1295

 Score = 31.2 bits (69), Expect = 3.1,   Method: Compositional matrix adjust.
 Identities = 11/25 (44%), Positives = 15/25 (60%)
 Frame = -3

Query: 558  CVPNHCEHGGKCSQTWDSFKCTCDE 582
            C  + C  GGKC + W++F C C E
Sbjct: 1050 CQSSPCTLGGKCKEGWNTFTCDCPE 976
>14158
          Length = 668

 Score = 29.6 bits (65), Expect = 7.5,   Method: Compositional matrix adjust.
 Identities = 21/50 (42%), Positives = 26/50 (52%), Gaps = 1/50 (2%)
 Frame = +3

Query: 548 TIDMC-AIIDRCVPNHCEHGGKCSQTWDSFKCTCDETGYSGATCHNSIYE 596
           T D+C A ID C  N C +GG C    D + C C E GYSG  C   + +
Sbjct: 423 TGDVCDANIDDCQTNTCFYGGTCVDGIDHWSCICAE-GYSGQWCQKMVNQ 569
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|21312062|ref|NP_081051.1| transmembrane emp24
domain-containing protein 10 [Mus musculus]
         (219 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

03595                                                                  90   9e-19
19964                                                                  60   6e-10
38580                                                                  39   0.001
08616                                                                  27   5.3  
31320                                                                  27   5.7  
06122                                                                  27   6.5  
>03595
          Length = 1492

 Score = 89.7 bits (221), Expect = 9e-19,   Method: Compositional matrix adjust.
 Identities = 50/138 (36%), Positives = 79/138 (57%), Gaps = 2/138 (1%)
 Frame = +3

Query: 83  ILYAKEDATKGKFAFTTEDYDMFEVCFESKGTGRI-PDQL-VILDMKHGVEAKNYEEIAK 140
           I+ ++  A +G+F FT+       +C  S  T  +   QL V LD+  G  A +Y+++  
Sbjct: 45  IVMSRTYAAEGRFTFTSHSAGEHIICLNSNSTAWLYAGQLRVHLDISVGEHAVDYQQVQA 224

Query: 141 VEKLKPLEVELRRLEDLSESIVNDFAYMKKREEEMRDTNESTNTRVLYFSIFSMFCLIGL 200
            +KL  L++ +R+L D  E I  +  Y + REE  R T+ESTN RVL++SI     L+  
Sbjct: 225 KDKLSELQLRIRQLLDQVEQITKEQNYQRYREERFRQTSESTNHRVLWWSIAQTLILLLT 404

Query: 201 ATWQVFYLRRFFKAKKLI 218
             WQ+ +L+ FF+AKKL+
Sbjct: 405 GFWQMQHLKSFFQAKKLV 458
>19964
          Length = 901

 Score = 60.5 bits (145), Expect = 6e-10,   Method: Compositional matrix adjust.
 Identities = 37/153 (24%), Positives = 77/153 (50%), Gaps = 1/153 (0%)
 Frame = +2

Query: 67  AGGLRTHLKITDSAGHILYAKEDATKGKFAFTTEDYDMFEVCFESKGTGRIPDQLVILDM 126
            G L   +KI      +++  E  + GK+ F      +++ CF ++ +   P ++V+  M
Sbjct: 56  GGFLDIDVKIYGPDNKVIHQGERESNGKYTFAAHMDGIYKYCFSNQMSTMTP-KVVMFSM 232

Query: 127 KHGVEAKNYEEIAKVEKLK-PLEVELRRLEDLSESIVNDFAYMKKREEEMRDTNESTNTR 185
             G + K+ +     +     LE  + +L        ++  YM+ RE   R  N++TN+R
Sbjct: 233 DVGEKPKDQDGDKDSDASHGKLEEMVNQLSTALTGAKHEQEYMEVRERIHRAINDNTNSR 412

Query: 186 VLYFSIFSMFCLIGLATWQVFYLRRFFKAKKLI 218
           V+ ++ F    L+ ++  QV+YL+RFF+ ++++
Sbjct: 413 VVLWAFFEALVLVAMSLGQVYYLKRFFEVRRVV 511
>38580
          Length = 727

 Score = 39.3 bits (90), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 37/165 (22%), Positives = 68/165 (41%), Gaps = 8/165 (4%)
 Frame = +1

Query: 32  ISFHLPVNSRKCLREEIHKDLLVTGAYEITDQSGGAGGLRTHLKITDSAGHILYAKEDAT 91
           ++F LP N + C  E + K +  T  Y++       G     +++T   G +LY +    
Sbjct: 151 LTFELPDNEKMCFHELVDKGVKATIEYQVV----MGGNYDVDMELTAPTGQVLYKEVKKQ 318

Query: 92  KGKFAFTTEDYDMFEVCFESKGTGRIPDQLVILDMKHG----VEAKNYEEIAKVEKLKPL 147
              F +T +   +   CF S        ++V  D++ G    V   + + +  +  ++  
Sbjct: 319 YDSFTWTADVKGIHAFCF-SNEFSTFTHKVVYFDLQVGDDKPVGDTDGDHVTAMTSIENS 495

Query: 148 EV----ELRRLEDLSESIVNDFAYMKKREEEMRDTNESTNTRVLY 188
            V    EL+R+ DL         + + RE + R   E  N RVL+
Sbjct: 496 AVNLFEELKRVLDLQ-------THFRLREAQGRAFAEDVNERVLF 609
>08616
          Length = 2833

 Score = 27.3 bits (59), Expect = 5.3,   Method: Compositional matrix adjust.
 Identities = 13/33 (39%), Positives = 20/33 (60%)
 Frame = +1

Query: 36  LPVNSRKCLREEIHKDLLVTGAYEITDQSGGAG 68
           +P+ ++K  RE  H+ L V G   +TD +GG G
Sbjct: 136 VPLQTQKLCRESSHQ-LRVAGLVTVTDGAGGTG 231
>31320
          Length = 820

 Score = 26.9 bits (58), Expect = 5.7,   Method: Compositional matrix adjust.
 Identities = 24/92 (26%), Positives = 41/92 (44%)
 Frame = -3

Query: 98  TTEDYDMFEVCFESKGTGRIPDQLVILDMKHGVEAKNYEEIAKVEKLKPLEVELRRLEDL 157
           T   + MF+ CFES  + +    +    +K G+  +N  +     K    +V+ +R   L
Sbjct: 608 TLSIFVMFQACFESMVSNQTLKNIFYACVKVGLGHQNGGKSRTESKFNFFKVKYKR-PKL 432

Query: 158 SESIVNDFAYMKKREEEMRDTNESTNTRVLYF 189
           SE +V+ ++   +    M  T E T T   YF
Sbjct: 431 SEMLVSGWSLTLEMTNSMWSTVE-TKTDKTYF 339
>06122
          Length = 826

 Score = 26.9 bits (58), Expect = 6.5,   Method: Compositional matrix adjust.
 Identities = 13/24 (54%), Positives = 17/24 (70%), Gaps = 1/24 (4%)
 Frame = -2

Query: 179 NESTNTR-VLYFSIFSMFCLIGLA 201
           NEST T  +LY+SIFS++ LI   
Sbjct: 225 NESTTTEALLYYSIFSLYSLISFV 154
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|23821025|ref|NP_062739.2| restin [Mus musculus]
         (1391 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

18826                                                                  93   9e-19
10547                                                                  83   6e-16
26691                                                                  83   8e-16
20779                                                                  77   4e-14
20604                                                                  73   7e-13
07561                                                                  33   0.59 
24037                                                                  32   1.3  
11942                                                                  31   3.6  
33875                                                                  30   7.4  
>18826
          Length = 490

 Score = 92.8 bits (229), Expect = 9e-19,   Method: Composition-based stats.
 Identities = 41/70 (58%), Positives = 51/70 (72%)
 Frame = +3

Query: 56  DDFRVGERVWVNGNKPGFIQFLGETQFAPGQWAGIVLDEPIGKNDGSVAGVRYFQCEPLK 115
           + F +G+RVWV G + G I ++GET FAPG WAGIVLDEP GK      G RYFQCEP +
Sbjct: 246 EQFIIGQRVWVGGLRSGQIAYIGETHFAPGDWAGIVLDEPNGKKRWMRFGQRYFQCEPKR 425

Query: 116 GIFTRPSKLT 125
           GIF+R ++LT
Sbjct: 426 GIFSRLTRLT 455

 Score = 76.3 bits (186), Expect = 9e-14,   Method: Composition-based stats.
 Identities = 32/66 (48%), Positives = 46/66 (69%)
 Frame = +3

Query: 213 VGDRVLVGGTKAGVVRFLGETDFAKGEWCGVELDEPLGKNDGAVAGTRYFQCQPKYGLFA 272
           +G RV VGG ++G + ++GET FA G+W G+ LDEP GK      G RYFQC+PK G+F+
Sbjct: 258 IGQRVWVGGLRSGQIAYIGETHFAPGDWAGIVLDEPNGKKRWMRFGQRYFQCEPKRGIFS 437

Query: 273 PVHKVT 278
            + ++T
Sbjct: 438 RLTRLT 455
>10547
          Length = 856

 Score = 83.2 bits (204), Expect = 6e-16,   Method: Composition-based stats.
 Identities = 35/61 (57%), Positives = 42/61 (68%)
 Frame = +2

Query: 223 KAGVVRFLGETDFAKGEWCGVELDEPLGKNDGAVAGTRYFQCQPKYGLFAPVHKVTKIGF 282
           + G VR++GETDF  G W G++ DEP GKNDG+VAG RYF+CQPKYG F     V    F
Sbjct: 2   RRGTVRYVGETDFKPGMWVGIQYDEPHGKNDGSVAGKRYFECQPKYGGFVKPSNVEVGDF 181

Query: 283 P 283
           P
Sbjct: 182 P 184

 Score = 77.0 bits (188), Expect = 5e-14,   Method: Composition-based stats.
 Identities = 31/53 (58%), Positives = 39/53 (73%)
 Frame = +2

Query: 72  GFIQFLGETQFAPGQWAGIVLDEPIGKNDGSVAGVRYFQCEPLKGIFTRPSKL 124
           G ++++GET F PG W GI  DEP GKNDGSVAG RYF+C+P  G F +PS +
Sbjct: 8   GTVRYVGETDFKPGMWVGIQYDEPHGKNDGSVAGKRYFECQPKYGGFVKPSNV 166
>26691
          Length = 395

 Score = 82.8 bits (203), Expect = 8e-16,   Method: Composition-based stats.
 Identities = 40/80 (50%), Positives = 54/80 (67%)
 Frame = +2

Query: 198 LSEAGSVKKGERELKVGDRVLVGGTKAGVVRFLGETDFAKGEWCGVELDEPLGKNDGAVA 257
           L+E  S+   E+ L VG R+L+ G K GV+RF+G+T  A G WCG+EL +  G +DG V 
Sbjct: 92  LTEKESIPGAEK-LTVGKRILISGVKPGVLRFVGQTSLAPGYWCGIELFDASGLHDGEVD 268

Query: 258 GTRYFQCQPKYGLFAPVHKV 277
           G RYF C+P  G+FAP+ KV
Sbjct: 269 GRRYFTCKPFRGIFAPLDKV 328

 Score = 70.1 bits (170), Expect = 6e-12,   Method: Composition-based stats.
 Identities = 30/63 (47%), Positives = 43/63 (68%)
 Frame = +2

Query: 56  DDFRVGERVWVNGNKPGFIQFLGETQFAPGQWAGIVLDEPIGKNDGSVAGVRYFQCEPLK 115
           +   VG+R+ ++G KPG ++F+G+T  APG W GI L +  G +DG V G RYF C+P +
Sbjct: 122 EKLTVGKRILISGVKPGVLRFVGQTSLAPGYWCGIELFDASGLHDGEVDGRRYFTCKPFR 301

Query: 116 GIF 118
           GIF
Sbjct: 302 GIF 310
>20779
          Length = 490

 Score = 77.4 bits (189), Expect = 4e-14,   Method: Composition-based stats.
 Identities = 32/50 (64%), Positives = 40/50 (80%)
 Frame = +3

Query: 229 FLGETDFAKGEWCGVELDEPLGKNDGAVAGTRYFQCQPKYGLFAPVHKVT 278
           +LGET FA G WCGVELDE  GKNDG V G RYF+C+P++G+F P+ KV+
Sbjct: 3   YLGETQFAPGNWCGVELDEGSGKNDGTVDGIRYFECKPRFGVFVPIAKVS 152

 Score = 68.6 bits (166), Expect = 2e-11,   Method: Composition-based stats.
 Identities = 29/50 (58%), Positives = 39/50 (78%)
 Frame = +3

Query: 76  FLGETQFAPGQWAGIVLDEPIGKNDGSVAGVRYFQCEPLKGIFTRPSKLT 125
           +LGETQFAPG W G+ LDE  GKNDG+V G+RYF+C+P  G+F   +K++
Sbjct: 3   YLGETQFAPGNWCGVELDEGSGKNDGTVDGIRYFECKPRFGVFVPIAKVS 152
>20604
          Length = 678

 Score = 73.2 bits (178), Expect = 7e-13,   Method: Composition-based stats.
 Identities = 41/98 (41%), Positives = 50/98 (51%), Gaps = 2/98 (2%)
 Frame = +3

Query: 78  GETQFAPGQWAGIVLDEPIGKNDGSVAGVRYFQCEPLKGIFTRPSKLTRKVQAEDEANGL 137
           G   FA G W G+ LD+P GKNDGSV G+RYF C    GIF RP KL    + +      
Sbjct: 114 GTCAFAVGNWIGVELDQPEGKNDGSVKGIRYFNCRGRHGIFVRPDKLIWDKKRKGSRKST 293

Query: 138 QAAPGRTASPLSTAAATMVSSSPATPSNIP--HKPSQS 173
           QA   R     STA  +   S+ + PS  P  H P+ S
Sbjct: 294 QAGARR-----STANLSSSLSNLSAPSAAPSSHTPTSS 392

 Score = 60.5 bits (145), Expect = 4e-09,   Method: Composition-based stats.
 Identities = 24/41 (58%), Positives = 30/41 (73%)
 Frame = +3

Query: 231 GETDFAKGEWCGVELDEPLGKNDGAVAGTRYFQCQPKYGLF 271
           G   FA G W GVELD+P GKNDG+V G RYF C+ ++G+F
Sbjct: 114 GTCAFAVGNWIGVELDQPEGKNDGSVKGIRYFNCRGRHGIF 236
>07561
          Length = 1234

 Score = 33.5 bits (75), Expect = 0.59,   Method: Composition-based stats.
 Identities = 29/105 (27%), Positives = 52/105 (49%), Gaps = 2/105 (1%)
 Frame = +1

Query: 117 IFTRPSKLTRKVQAEDEANGLQAAPGRTASPLSTAAATMVSSSPATPSNIPHKPSQSTAK 176
           +FTR  +L+  +Q    +     APG  AS  ST+ A++  SSP+ PS    + S  T  
Sbjct: 766 LFTRRRRLS--LQCPPFSYRAGQAPGSPASQFSTSHASISESSPSQPST---RESSVTPD 930

Query: 177 EPSATPQISNLTKTASES--ISNLSEAGSVKKGERELKVGDRVLV 219
           +P  +P+ ++   + ++   I  + E   V+   +E  +  R+LV
Sbjct: 931 DPRPSPEQASGVSSDNQGPLIPFVRENLGVELTHQEYDLAVRLLV 1065
>24037
          Length = 2006

 Score = 32.3 bits (72), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 15/35 (42%), Positives = 24/35 (68%)
 Frame = +2

Query: 540 EIKALHTATEKLSKENESLRSKLDHANKENSDVIA 574
           E+  L T ++KLSK+NE++  KL  A+   ++VIA
Sbjct: 233 EVHVLRTESQKLSKQNEAIHRKLRQADDHRAEVIA 337
>11942
          Length = 2252

 Score = 30.8 bits (68), Expect = 3.6,   Method: Compositional matrix adjust.
 Identities = 27/100 (27%), Positives = 49/100 (49%)
 Frame = +1

Query: 334  LLTETSSRYARKISGTTALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELAL 393
            L+   + ++AR++   T LQ+ L E Q  + QL ++    RA    + + V E++Q+L  
Sbjct: 1234 LVAAAADKHARQM---TLLQDDLDEAQNRVSQLESKLQEARASTGSSDARVAELQQQL-- 1398

Query: 394  ARDGHDQHVLELEAKMDQLRTMVEAADREKVELLNQLEEE 433
                     +  + K D LRT   A  +   + ++QLE+E
Sbjct: 1399 ------DDSIGFKDKYDNLRTQATAMKQRYEDRISQLEQE 1500
>33875
          Length = 624

 Score = 30.0 bits (66), Expect = 7.4,   Method: Compositional matrix adjust.
 Identities = 25/97 (25%), Positives = 40/97 (41%), Gaps = 15/97 (15%)
 Frame = -3

Query: 122 SKLTRKVQAEDEAN--GLQAAPGRTASPLSTAAATMVSSSP-------------ATPSNI 166
           S + R +   ++AN   L+ A GR AS +    ++  S+S              A   +I
Sbjct: 343 SXVARNIPLYNKANWTALRQAVGRIASDIQNLXSSKNSASTEQLWDCFKTQLLNAVQEHI 164

Query: 167 PHKPSQSTAKEPSATPQISNLTKTASESISNLSEAGS 203
           PHK + S   +P  TP+I  L      +     + GS
Sbjct: 163 PHKQATSKTHQPWITPEICRLMNRRDRAYKKWKKTGS 53
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|10092608|ref|NP_038569.1| glutathione S-transferase,
pi 1 [Mus musculus]
         (210 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

35754                                                                  89   1e-18
02955                                                                  67   6e-12
06833                                                                  67   8e-12
28643                                                                  30   0.65 
23210                                                                  29   1.6  
25671                                                                  28   3.6  
00841                                                                  27   7.3  
>35754
          Length = 581

 Score = 89.0 bits (219), Expect = 1e-18,   Method: Compositional matrix adjust.
 Identities = 51/172 (29%), Positives = 93/172 (54%), Gaps = 2/172 (1%)
 Frame = -2

Query: 37  DTWMQGLLKPTCLYGQLPKFEDGDLTLYQSNAILRHLGRSLGLYGKNQREAAQMDMVNDG 96
           D W++        +  LP + DGD+ L QSNAILR++ R   L G+   E+A+++M+ + 
Sbjct: 529 DAWLKVKSSLGLDFPNLPYYIDGDIKLTQSNAILRYIARKHNLMGETPLESARVEMMLEN 350

Query: 97  VEDLRGKYVTLIYT-NYENGKNDYVKALPGHLKPFETLLSQNQGGKAFIVGDQISFADYN 155
             D R   V ++Y   Y +   +Y   +   L  F   L+     K +  GD+++ AD++
Sbjct: 349 AMDFRNGVVRMVYNPKYTDLLEEYKPKVKETLAGFNKYLAD----KKWFAGDKVTVADFH 182

Query: 156 LLDLLLIHQVL-APGCLDNFPLLSAYVARLSARPKIKAFLSSPEHVNRPING 206
           + +LL  H+++     L ++P L+A++A   A P IK +++S + + RP+N 
Sbjct: 181 MYELLDQHRLMIGADVLKDYPKLTAFMAAFEALPAIKKYMASDKFMKRPVNN 26
>02955
          Length = 1322

 Score = 66.6 bits (161), Expect = 6e-12,   Method: Compositional matrix adjust.
 Identities = 55/203 (27%), Positives = 89/203 (43%), Gaps = 7/203 (3%)
 Frame = +1

Query: 1   MPPYTIVYFPVRGRCEAMRMLLADQGQSWKEEVVTIDTW-MQGLLKPTCLYGQLPKFEDG 59
           M    + YF VRG+ E +R+L    G  ++++ +    W      K    YGQ+P     
Sbjct: 16  MSDIKLYYFNVRGKGEFLRLLFRAAGVQFEDKRIERADWGPDSDAKKATPYGQVPYVIYQ 195

Query: 60  DLTLYQSNAILRHLGRSLGLYGKNQREAAQMDMVNDGVEDL-RGKYVTLIYTNYENGKND 118
                QS A+  +  R  G YGK   +A + + +   ++DL  G             K +
Sbjct: 196 GKKRGQSIAMGTYFARKFGFYGKTDEDAWKQEEIMHLIDDLIVGPNRAWFLEQDPQKKAE 375

Query: 119 YVKAL-----PGHLKPFETLLSQNQGGKAFIVGDQISFADYNLLDLLLIHQVLAPGCLDN 173
             + L     P +L  FE LL++N G + + VGD ++ AD  L D+L     + P  L +
Sbjct: 376 RTRELTEVQYPRYLSSFERLLAEN-GDQGYSVGDSVTLADLCLHDVLETVLGVDPRALXS 552

Query: 174 FPLLSAYVARLSARPKIKAFLSS 196
           FPL     A +   P +K +L+ 
Sbjct: 553 FPLQRKLRANVENLPALKEYLAK 621
>06833
          Length = 882

 Score = 66.6 bits (161), Expect = 8e-12,   Method: Compositional matrix adjust.
 Identities = 59/210 (28%), Positives = 90/210 (42%), Gaps = 12/210 (5%)
 Frame = +3

Query: 1   MPPYTIVYFPVRGRCEAMRMLLADQGQSWKEEVVTIDTWMQGLLKPTCLYGQLP--KFED 58
           M    + YF  RG  E  R+LLA  GQ +++     + W Q   K    +GQ P   F D
Sbjct: 90  MEDVKLYYFDSRGFGEVSRLLLALAGQDYQDVRFDREEWAQ-TYKAEAPFGQGPFLAFTD 266

Query: 59  GDL----TLYQSNAILRHLGRSLGLYGKNQREAAQMDMVNDGVEDLRGKYVTLIYTNYEN 114
                   + QS+AI   L R  GLYG + ++ A +D V     D+   +  ++ T   +
Sbjct: 267 SKTKKLKKIGQSSAIACFLAREFGLYGSSNQDGAVIDQVVHLYRDMVVAWQKVMLTEDAD 446

Query: 115 GKNDYVKAL-----PGHLKPFETLLSQNQGGKAFIVGDQISFADYNLLDLLL-IHQVLAP 168
            K +  K L     P     F  LL +N     F VG+ I+ AD    D +  + +V   
Sbjct: 447 KKTEAHKKLMEEEFPKFFGHFNKLLEEN-SDSPFFVGNSITLADVYXYDXIFQVKKVTGY 623

Query: 169 GCLDNFPLLSAYVARLSARPKIKAFLSSPE 198
               N P L     +++  P IKA+++  E
Sbjct: 624 DPCANHPSLQTLYDQVAEIPNIKAYVAQEE 713
>28643
          Length = 748

 Score = 30.0 bits (66), Expect = 0.65,   Method: Compositional matrix adjust.
 Identities = 13/23 (56%), Positives = 17/23 (73%)
 Frame = +2

Query: 51  GQLPKFEDGDLTLYQSNAILRHL 73
           GQLP F+DGDL + +S AI  +L
Sbjct: 122 GQLPTFKDGDLVVNESGAICDYL 190
>23210
          Length = 944

 Score = 28.9 bits (63), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 20/75 (26%), Positives = 33/75 (44%)
 Frame = -3

Query: 121 KALPGHLKPFETLLSQNQGGKAFIVGDQISFADYNLLDLLLIHQVLAPGCLDNFPLLSAY 180
           +  P        +L++N     F VG  +S AD  L D++     +       +P L A 
Sbjct: 450 ETFPNAFGXXNKMLTENBPNGVF-VGKXLSLADLCLXDIMFXLTPMYDAG-TXYPALKAL 277

Query: 181 VARLSARPKIKAFLS 195
             ++   PKIKA+L+
Sbjct: 276 REKVETNPKIKAYLA 232
>25671
          Length = 441

 Score = 27.7 bits (60), Expect = 3.6,   Method: Compositional matrix adjust.
 Identities = 24/62 (38%), Positives = 29/62 (46%), Gaps = 2/62 (3%)
 Frame = +2

Query: 89  QMDMVNDGVEDLRGKYVTLIYTNYENGKNDYVKALPG--HLKPFETLLSQNQGGKAFIVG 146
           QMD V    +D     + L  TN+  G    ++A PG  HL P  T LS   GG A   G
Sbjct: 251 QMDGVGVTNDDPSKAVMVLAATNFPLGHRRGLEAPPGETHLHP--TALS---GGPACAAG 415

Query: 147 DQ 148
           DQ
Sbjct: 416 DQ 421
>00841
          Length = 1359

 Score = 26.6 bits (57), Expect = 7.3,   Method: Compositional matrix adjust.
 Identities = 11/38 (28%), Positives = 18/38 (47%)
 Frame = -2

Query: 140 GKAFIVGDQISFADYNLLDLLLIHQVLAPGCLDNFPLL 177
           G   I G  +    YN +D+  ++ V    CL  FP++
Sbjct: 986 GSCVIKGKFVPCVSYNYIDISFVYFVSXXXCLLKFPII 873
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|125661048|ref|NP_919444.2| A kinase (PRKA) anchor
protein (yotiao) 9 [Mus musculus]
         (3779 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

12039                                                                  94   1e-18
>12039
          Length = 1726

 Score = 93.6 bits (231), Expect = 1e-18,   Method: Compositional matrix adjust.
 Identities = 63/148 (42%), Positives = 85/148 (57%), Gaps = 4/148 (2%)
 Frame = +2

Query: 3522 SEKEVWNREKLSLQKALKRAEAKVYKLKAELRNDALLRN---LGPDTDHAALQKIYNKYL 3578
             E+ +W  E+ +LQ AL  AE ++ +L+ ELR      N      D D   +Q+IY KYL
Sbjct: 569  GERSLWASERSNLQLALDSAEHEIDRLRKELRAFRGRFNSEGFMVDADGDKMQRIYGKYL 748

Query: 3579 RASSFRKALIYQKKYXXXXXXXFQECEDVTLGVLARMGGHLALK-DSKTITNHPKAFSRF 3637
            RA SFRKAL+YQKKY       +Q+ E  TL V+A MGG  +   D      H + +S F
Sbjct: 749  RAESFRKALVYQKKYLLLLLGGYQDSEQETLAVIATMGGQPSSTLDLAMRRRHHRLYSMF 928

Query: 3638 RSAVRVSIAISRMKFLVRRWQQVTSTSS 3665
            RSA R+ +AI RMK+LVRRW++     S
Sbjct: 929  RSAARMVVAIFRMKYLVRRWKRAMRIGS 1012
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|149251219|ref|XP_203999.8| PREDICTED: Rap guanine
nucleotide exchange factor (GEF) 2 [Mus musculus]
         (1668 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

27307                                                                  92   1e-18
12552                                                                  89   1e-17
27562                                                                  49   2e-09
32091                                                                  52   3e-06
38751                                                                  46   1e-04
26155                                                                  43   0.001
03831                                                                  41   0.005
20073                                                                  38   0.032
01502                                                                  34   0.49 
02951                                                                  34   0.53 
25998                                                                  30   7.0  
>27307
          Length = 415

 Score = 92.4 bits (228), Expect = 1e-18,   Method: Compositional matrix adjust.
 Identities = 47/100 (47%), Positives = 67/100 (67%)
 Frame = -1

Query: 755 SSSNPDLLQSHHRILDFSTTPDLPDQVLRVFKADQQSRYIMISKDTTAKEVVIQAIREFA 814
           S+SNPDL      +L      D P+ V++V++ADQ  +++ I K+TTAKEVV+ A++EF+
Sbjct: 292 SASNPDL---SSMMLGPDDRSDFPEHVVKVYRADQSFKFLQIHKETTAKEVVLWAMQEFS 122

Query: 815 VTATPEQYSLCEVSVTPEGVIKQRRLPDQLSKLADRIQLS 854
           +      YSLCEV+V  E  IKQRRLPD LS L +R+ L+
Sbjct: 121 LADNTGDYSLCEVTVESEMFIKQRRLPDTLSNLTERLNLN 2
>12552
          Length = 1266

 Score = 89.4 bits (220), Expect = 1e-17,   Method: Compositional matrix adjust.
 Identities = 53/169 (31%), Positives = 86/169 (50%), Gaps = 1/169 (0%)
 Frame = -3

Query: 885  LLQLSTVEVATQLSMRNFELFRNIEPTEYIDDLFKLKSKTSCA-NLKKFEEVINQETFWV 943
            +L++S  E A+Q+ + +  +F++I+P E     +  K K   A N+  F    N   FWV
Sbjct: 979  VLRVSPEEFASQIXLMDLPVFKSIQPDELTSCAWTTKEKLIKAPNVVAFTRRFNHVNFWV 800

Query: 944  ASEILRETNQLKRMKIIKHFIKIALHCRECKNFNSMFAIISGLNLAPVARLRTTWEKLPN 1003
              EIL       R  ++ HFIKIA    E  N +++ A+IS L  A + RL  TW  L  
Sbjct: 799  QREILNCQTLKTRADVLAHFIKIAKKLLELNNLHAVMAVISALQSAAIFRLSGTWMMLSK 620

Query: 1004 KYEKLFQDLQDLFDPSRNMAKYRNVLSGQNLQPPVIPLFPVIKKDLTFL 1052
            K + +++ + D+F    N  K R+V+   N++ P IP   +   DL ++
Sbjct: 619  KDKLMYERMADMFSECNNRQKLRDVM--DNVKLPCIPYLGLYLTDLIYI 479
>27562
          Length = 399

 Score = 49.3 bits (116), Expect(2) = 2e-09,   Method: Compositional matrix adjust.
 Identities = 21/42 (50%), Positives = 31/42 (73%)
 Frame = -1

Query: 284 EKDPIDRTDDDIEQLLEFMHQLPAFANMTMSVRRELCAVMVF 325
           +KDP +RT++DIE L++FM    AFA+++   R+ LC VMVF
Sbjct: 126 KKDPSERTENDIEILMDFMQHFQAFASLSHMTRQALCTVMVF 1

 Score = 32.3 bits (72), Expect(2) = 2e-09,   Method: Compositional matrix adjust.
 Identities = 21/47 (44%), Positives = 23/47 (48%)
 Frame = -3

Query: 246 DLSGLPETAVXXXXXXXXXXXXRASDPLMSRDIVRDCLEKDPIDRTD 292
           DL+GL E+ V             A      RD VRDCLEK PI RTD
Sbjct: 241 DLTGLMESVVDSDEEEGYADSTEALFQFPVRDTVRDCLEKRPI-RTD 104
>32091
          Length = 348

 Score = 51.6 bits (122), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 35/102 (34%), Positives = 57/102 (55%), Gaps = 1/102 (0%)
 Frame = +3

Query: 878 LRESQISLLQLSTVEVATQLSMRNFELFRNIEPTEYIDDLF-KLKSKTSCANLKKFEEVI 936
           L  S   LL   T+++A Q+++ + +LF+ IE  E +  L+ K +S+    NL  F E  
Sbjct: 45  LSSSTPDLLSFKTLDIAEQMTLLDAQLFQKIEIPEVL--LWAKEQSEELSPNLTTFTEHF 218

Query: 937 NQETFWVASEILRETNQLKRMKIIKHFIKIALHCRECKNFNS 978
           N+ ++W  + IL + +  +R K +  FIKI    R+ KNFNS
Sbjct: 219 NKMSYWCRTRILTQEDPKEREKYLMKFIKIMRCLRKLKNFNS 344
>38751
          Length = 329

 Score = 46.2 bits (108), Expect = 1e-04,   Method: Composition-based stats.
 Identities = 23/62 (37%), Positives = 40/62 (64%)
 Frame = +3

Query: 575 GGSEKGFGIFVDSVDSCSKATEAGLKRGDQILEVNGQNFENIQLSKAMEILRNNTHLSIT 634
           GG E G  I V  ++   +A + GL  GD+IL+VNG +F ++  ++A+ I+RN  ++ +T
Sbjct: 15  GGKEYGTPIVVYVIEEGCQAEQQGLNIGDRILDVNGTDFTHLTHAEAVTIMRNAWNVIMT 194

Query: 635 VK 636
           V+
Sbjct: 195 VQ 200
>26155
          Length = 693

 Score = 42.7 bits (99), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 19/40 (47%), Positives = 27/40 (67%), Gaps = 1/40 (2%)
 Frame = -1

Query: 1038 VIPLFPVIKKDLTFLHEGNDSK-VDGLVNFEKLRMIAKEI 1076
            VIP F +  KDL FL+EG  ++  DG +NFEK  ++AK +
Sbjct: 633  VIPFFSLFVKDLYFLNEGCSNRHCDGNINFEKCWVLAKHV 514
>03831
          Length = 1143

 Score = 40.8 bits (94), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 18/45 (40%), Positives = 28/45 (62%)
 Frame = +3

Query: 582 GIFVDSVDSCSKATEAGLKRGDQILEVNGQNFENIQLSKAMEILR 626
           G ++ SVD  S A   GLK GD+I+EVNG+N E    +  ++ ++
Sbjct: 654 GQYIGSVDPNSPAETGGLKEGDRIIEVNGENIETTNHTAVIQNIK 788

 Score = 40.8 bits (94), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 22/40 (55%), Positives = 26/40 (65%), Gaps = 1/40 (2%)
 Frame = +3

Query: 577 SEKG-FGIFVDSVDSCSKATEAGLKRGDQILEVNGQNFEN 615
           +EKG  G F+  VD  S A  AGLK GD+I+EVNG N  N
Sbjct: 189 AEKGKAGQFIGKVDEGSPAEAAGLKAGDRIVEVNGTNIGN 308
>20073
          Length = 582

 Score = 38.1 bits (87), Expect = 0.032,   Method: Composition-based stats.
 Identities = 26/89 (29%), Positives = 45/89 (50%), Gaps = 2/89 (2%)
 Frame = +3

Query: 569 LPFILLGGSEKGFGIFVDSVDSCSKATEAG-LKRGDQILEVNGQNFENIQLSKAMEILR- 626
           L F ++GG E+   I++  +     A     LKRGDQ+L VNG + E     KA+E+L+ 
Sbjct: 6   LGFNVMGGKEQSSPIYISRIIPGGVADRLNCLKRGDQLLSVNGVSVEGEYHEKAVELLKL 185

Query: 627 NNTHLSITVKTNLFVFKELLTRLSEEKRN 655
               + + V+    + +E+  R   +K +
Sbjct: 186 AQGSVRLVVRYTPQILEEMEARFERQKNS 272
>01502
          Length = 1949

 Score = 34.3 bits (77), Expect = 0.49,   Method: Composition-based stats.
 Identities = 18/54 (33%), Positives = 31/54 (57%)
 Frame = +1

Query: 582 GIFVDSVDSCSKATEAGLKRGDQILEVNGQNFENIQLSKAMEILRNNTHLSITV 635
           GI+V  +   S A   GL+  D+IL++NG++F  +   +A+E +R    L + V
Sbjct: 34  GIYVTFIYENSPAARCGLQLHDKILQLNGKDFTVVTHKQAVENIRKKPVLKMLV 195
>02951
          Length = 1076

 Score = 33.9 bits (76), Expect = 0.53,   Method: Composition-based stats.
 Identities = 18/54 (33%), Positives = 31/54 (57%)
 Frame = +2

Query: 582 GIFVDSVDSCSKATEAGLKRGDQILEVNGQNFENIQLSKAMEILRNNTHLSITV 635
           GI+V  +   S A   GL+  D+IL++NG++F  +   +A+E +R    L + V
Sbjct: 20  GIYVTFIYENSPAARCGLQLHDKILQLNGKDFTVVTHKQAVENIRKKPVLKMLV 181
>25998
          Length = 439

 Score = 30.4 bits (67), Expect = 7.0,   Method: Compositional matrix adjust.
 Identities = 14/50 (28%), Positives = 27/50 (54%)
 Frame = +1

Query: 615 NIQLSKAMEILRNNTHLSITVKTNLFVFKELLTRLSEEKRNGAPHLPKIG 664
           ++ ++  + I++   HL  TVK  +   ++L+ ++   K N APH P  G
Sbjct: 253 SVAMAPLVPIVQRQDHLEKTVKGCVKRMEDLVHQIKSHKPNSAPHHPSTG 402
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|163644277|ref|NP_031485.3| adaptor protein complex
AP-2, alpha 2 subunit [Mus musculus]
         (938 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

35332                                                                  91   2e-18
>35332
          Length = 396

 Score = 90.9 bits (224), Expect = 2e-18,   Method: Composition-based stats.
 Identities = 43/50 (86%), Positives = 47/50 (94%)
 Frame = -1

Query: 1   MPAVSKGDGMRGLAVFISDIRNCKSKEAEIKRINKELANIRSKFKGDKAL 50
           MPA +KGDGMRGLAVFISDIRNCKSKEAE+KRINKELANIRSKFKG + +
Sbjct: 285 MPA-AKGDGMRGLAVFISDIRNCKSKEAEVKRINKELANIRSKFKGKRTV 139
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|21703770|ref|NP_663360.1| myeloid leukemia factor 2
homolog [Mus musculus]
         (247 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

24413                                                                  89   2e-18
06896                                                                  85   3e-17
07626                                                                  28   4.9  
>24413
          Length = 488

 Score = 88.6 bits (218), Expect = 2e-18,   Method: Compositional matrix adjust.
 Identities = 37/72 (51%), Positives = 56/72 (77%)
 Frame = -2

Query: 116 APKVYQETSEMRSAPGGIRETRRTVRDSDSGLEQMSIGHHIRDRAHILQRSRNHRTGDQE 175
           +P+  + +S     PGG+RETR+TVR+S+SG+E+M++G HI +R H+++R RN RTGD E
Sbjct: 217 SPRCTRSSSSTTQGPGGVRETRKTVRNSESGVEKMAVGRHIGNRGHVVERQRNRRTGDHE 38

Query: 176 ERQDYINLDESE 187
           E Q++IN+DE E
Sbjct: 37  ENQEFINIDEEE 2
>06896
          Length = 610

 Score = 84.7 bits (208), Expect = 3e-17,   Method: Compositional matrix adjust.
 Identities = 43/79 (54%), Positives = 59/79 (74%)
 Frame = -3

Query: 97  NCQTFSSSTVISYSNTGDGAPKVYQETSEMRSAPGGIRETRRTVRDSDSGLEQMSIGHHI 156
           N Q FS S+ +SYS+ G   PKVYQ +S     PGG+RETR+TVR+S+SG+E+M++G HI
Sbjct: 239 NGQMFSQSSFVSYSSMGGAQPKVYQASSSTTQGPGGVRETRKTVRNSESGVEKMAVGRHI 60

Query: 157 RDRAHILQRSRNHRTGDQE 175
            +R H+++R RN RTGD E
Sbjct: 59  GNRGHVVERQRNRRTGDHE 3
>07626
          Length = 1423

 Score = 27.7 bits (60), Expect = 4.9,   Method: Compositional matrix adjust.
 Identities = 16/43 (37%), Positives = 21/43 (48%)
 Frame = -2

Query: 120 YQETSEMRSAPGGIRETRRTVRDSDSGLEQMSIGHHIRDRAHI 162
           YQ      ++PG + E           LEQM +G H+RD AHI
Sbjct: 237 YQFVDGTDTSPGQLAEQDHAF--DVVVLEQMDVGAHLRDGAHI 115
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|8567410|ref|NP_038709.1| synapsin II isoform IIb [Mus
musculus]
         (479 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

11472                                                                  60   2e-18
19672                                                                  32   0.55 
14870                                                                  30   2.9  
02108                                                                  28   6.6  
>11472
          Length = 1283

 Score = 60.5 bits (145), Expect(2) = 2e-18,   Method: Compositional matrix adjust.
 Identities = 29/50 (58%), Positives = 36/50 (72%)
 Frame = -2

Query: 174  KVVRSFRPDFVLIRQHAFGMAENEDFRHLVIGMQYAGLPSINSLESIYNF 223
            +V RSFRPDFVLIRQ       + DFR  ++G++Y G+PSINSL SIY F
Sbjct: 1222 QVARSFRPDFVLIRQPP--RDGSSDFRSTILGLKYGGVPSINSLHSIYQF 1079

 Score = 49.7 bits (117), Expect(2) = 2e-18,   Method: Compositional matrix adjust.
 Identities = 18/38 (47%), Positives = 31/38 (81%)
 Frame = -1

Query: 225  DKPWVFAQMVAIFKTLGGEKFPLIEQTYYPNHREMLTL 262
            DKPWVF+ ++ + + LG + FPLIEQT++PN R+++++
Sbjct: 1007 DKPWVFSHLLQLQRRLGRDGFPLIEQTFFPNPRDLVSV 894
>19672
          Length = 458

 Score = 32.0 bits (71), Expect = 0.55,   Method: Composition-based stats.
 Identities = 13/34 (38%), Positives = 21/34 (61%)
 Frame = +3

Query: 421 RTPALSPQRPLTTQQPQSGTLKEPDSSKTPPQRP 454
           R+PAL P  P++   PQ  + +   + ++PPQRP
Sbjct: 33  RSPALPPG-PVSPSAPQRSSPQRSSTXRSPPQRP 131
>14870
          Length = 1128

 Score = 29.6 bits (65), Expect = 2.9,   Method: Compositional matrix adjust.
 Identities = 13/40 (32%), Positives = 20/40 (50%)
 Frame = -1

Query: 224 CDKPWVFAQMVAIFKTLGGEKFPLIEQTYYPNHREMLTLP 263
           CD PW   Q + IF       FP++E+T+    R +  +P
Sbjct: 891 CDAPWTLCQALFIF-------FPILEKTFPVFFRTLFIMP 793
>02108
          Length = 1087

 Score = 28.5 bits (62), Expect = 6.6,   Method: Compositional matrix adjust.
 Identities = 16/42 (38%), Positives = 22/42 (52%)
 Frame = -3

Query: 205 GMQYAGLPSINSLESIYNFCDKPWVFAQMVAIFKTLGGEKFP 246
           G Q A L S  SL +  N CD+P  ++Q V  +   G  +FP
Sbjct: 953 GSQIAPLVSTYSLSNKINHCDEP-FWSQSVVTWSQAGISRFP 831
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|9790121|ref|NP_062704.1| non-metastatic cells 3,
protein expressed in [Mus musculus]
         (169 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

32935                                                                  87   2e-18
02656                                                                  75   1e-14
02733                                                                  70   6e-13
14087                                                                  33   0.072
31902                                                                  33   0.081
>32935
          Length = 1188

 Score = 87.4 bits (215), Expect = 2e-18,   Method: Compositional matrix adjust.
 Identities = 51/133 (38%), Positives = 75/133 (56%), Gaps = 3/133 (2%)
 Frame = +2

Query: 22  ERTFLAVKPDGVQRRLVGEIVRRFERKGFKLVALKLVQASEELLREHYVELREKPFYSRL 81
           ERT   +KPD V++  +G+++ +  +KGF +  L++ +       E Y E R KPF + L
Sbjct: 278 ERTLGLIKPDAVEK--LGQVLDKILQKGFLISRLRMCKLDRNTALEFYQEHRSKPFLNAL 451

Query: 82  VKYMSSGPVVAMVWQWLDVVHASRALIGATDPGDA---MPGTIRGDFCMEVGKNVIHGSD 138
           + Y++SGPVVA      + V A R  IG TDP  A    P +IR  +  +V  N +HGSD
Sbjct: 452 LDYVTSGPVVAFEIVGENAVGAWREAIGPTDPSLARKEAPTSIRAQYGTDVTCNAVHGSD 631

Query: 139 SVESAHREIALWF 151
           S  SA RE+  +F
Sbjct: 632 SPGSAAREVEFFF 670

 Score = 41.6 bits (96), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 36/147 (24%), Positives = 64/147 (43%), Gaps = 12/147 (8%)
 Frame = +1

Query: 18  SGVNERTFLAVKPDGVQRRLVGEIVRRFERKGFKLVA---LKLVQASEELLREHYVELRE 74
           + +   T   +KP   +  + G+I+      GF++ +     L +A+ E   E Y  +  
Sbjct: 700 ASIGNCTCCIIKPSAFKAGVAGKIINAITEAGFRVGSAEMFTLEKANAEEFLEVYKGVVH 879

Query: 75  KPFYSRLVKYMSSGPVVAMVWQWLDVVHAS------RALIGATDPGDA---MPGTIRGDF 125
           +  Y  +V  ++SGP +A+        +AS      R L G  DP  A    P T+R  F
Sbjct: 880 E--YPAMVTELTSGPCLALEIVGGSGTNASLLAPAFRELAGPVDPEIARHLRPRTLRAMF 1053

Query: 126 CMEVGKNVIHGSDSVESAHREIALWFR 152
             +  KN +H +D  +    E+  +F+
Sbjct: 1054GTDKIKNAVHCTDLPDDGPLEVEYFFK 1134
>02656
          Length = 2642

 Score = 75.5 bits (184), Expect = 1e-14,   Method: Composition-based stats.
 Identities = 42/133 (31%), Positives = 69/133 (51%), Gaps = 3/133 (2%)
 Frame = +3

Query: 22   ERTFLAVKPDGVQRRLVGEIVRRFERKGFKLVALKLVQASEELLREHYVELREKPFYSRL 81
            E+T   +KPDG   +    I+ +  + GF++ A K    + ++    Y + ++K +Y  L
Sbjct: 1074 EQTVAMIKPDGYGTK--DAIIEKIHQAGFRIAARKETTITRDIAESFYDDQKDKDYYESL 1247

Query: 82   VKYMSSGPVVAMVWQWLDVVHASRALIGATDPGDAM---PGTIRGDFCMEVGKNVIHGSD 138
            V++M+SGP + MV      V   R  IG TDP  A    P ++R  F  +V +N +HG+ 
Sbjct: 1248 VEHMTSGPTMFMVLSREGAVDGWREEIGPTDPTKAKEQNPNSLRAQFGTDVLQNAVHGAS 1427

Query: 139  SVESAHREIALWF 151
            S E A ++I   F
Sbjct: 1428 SSEEAKKKIKAVF 1466

 Score = 70.5 bits (171), Expect = 3e-13,   Method: Composition-based stats.
 Identities = 42/134 (31%), Positives = 68/134 (50%), Gaps = 4/134 (2%)
 Frame = +3

Query: 22  ERTFLAVKPDGVQRRLVGEIVRRFERKGFKLVALKLVQASEELLREHYVELREKPFYSRL 81
           +RT   ++PD         I+ + +  GF++   K V  ++E   E Y E   +P+Y  L
Sbjct: 669 QRTLALIRPDAFANN-KDAILEKIKEAGFQIALHKEVSLTKEQAEEFYKEHAGQPYYDEL 845

Query: 82  VKYMSSGPVVAMVWQWLDVVHASRALIGATDPGD---AMPGTIRGDFCME-VGKNVIHGS 137
              MSSGP++A+     D V   R ++G TD  +   A P  +R  F ++    N +HGS
Sbjct: 846 TDRMSSGPLLALGLAREDAVENWREMLGPTDVEEAKTAAPDCLRAQFAVDSTAINQLHGS 1025

Query: 138 DSVESAHREIALWF 151
           DS +SA +E+  +F
Sbjct: 1026DSTQSAKKELEFFF 1067

 Score = 61.6 bits (148), Expect = 1e-10,   Method: Composition-based stats.
 Identities = 49/156 (31%), Positives = 79/156 (50%), Gaps = 9/156 (5%)
 Frame = +3

Query: 5   VLTIFANLFPS-AYSGVNE-RTFLAVKPDGVQRRLVGEIVRRFERKGFKLVALKLVQASE 62
           V+    +L P+ +Y  V E  T   +KP+ V    V EI+   + +G  + A +  Q +E
Sbjct: 156 VVNYGGDLTPAGSYEEVEEGYTVAIIKPNVVANGKVDEILAEMKARGINVKAQEERQLTE 335

Query: 63  ELLREHYVELREKPFYSRLVKYMSSGPVVAMVW---QWLD-VVHASRALIG---ATDPGD 115
           +  RE Y  L+ + ++  LV +M+SGP   +V    Q  D VV   R ++G     D  +
Sbjct: 336 DEAREFYSHLQGEEYFEDLVAFMASGPSHVLVLTEGQEDDSVVKDWRDMLGPPTVEDAKE 515

Query: 116 AMPGTIRGDFCMEVGKNVIHGSDSVESAHREIALWF 151
             P ++R  +      N +HGSDS E+A RE+A +F
Sbjct: 516 QAPESLRARYGQGGLMNAVHGSDSKETAARELAFFF 623
>02733
          Length = 853

 Score = 69.7 bits (169), Expect = 6e-13,   Method: Compositional matrix adjust.
 Identities = 36/112 (32%), Positives = 59/112 (52%), Gaps = 3/112 (2%)
 Frame = -1

Query: 43  RRFERKGFKLVALKLVQASEELLREHYVELREKPFYSRLVKYMSSGPVVAMVWQWLDVVH 102
           R+  + GF++ A K    + ++    Y + ++K +Y  LV++M+SGP + MV      V 
Sbjct: 748 RKIHQAGFRIAARKETTITRDIAESFYDDQKDKDYYESLVEHMTSGPTMFMVLSREGAVD 569

Query: 103 ASRALIGATDPGDAM---PGTIRGDFCMEVGKNVIHGSDSVESAHREIALWF 151
             R  IG TDP  A    P ++R  F  +V +N +HG+ S E A ++I   F
Sbjct: 568 GWREEIGPTDPTKAKEQNPNSLRAQFGTDVLQNAVHGASSSEEAKKKIKAVF 413
>14087
          Length = 2025

 Score = 32.7 bits (73), Expect = 0.072,   Method: Compositional matrix adjust.
 Identities = 16/37 (43%), Positives = 21/37 (56%)
 Frame = +2

Query: 77  FYSRLVKYMSSGPVVAMVWQWLDVVHASRALIGATDP 113
           +Y  LV++M+SGP + MV      V   R  IG TDP
Sbjct: 2   YYESLVEHMTSGPTMFMVLSREGAVDGWREEIGPTDP 112
>31902
          Length = 546

 Score = 32.7 bits (73), Expect = 0.081,   Method: Compositional matrix adjust.
 Identities = 17/38 (44%), Positives = 21/38 (55%), Gaps = 3/38 (7%)
 Frame = +1

Query: 105 RALIGATDPGDA---MPGTIRGDFCMEVGKNVIHGSDS 139
           R  IG TDP  A    P +IR  +  +V  N +HGSDS
Sbjct: 391 REAIGPTDPSLARKEAPTSIRAQYGTDVTCNAVHGSDS 504
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|21313438|ref|NP_079864.1| exocyst complex component 2
[Mus musculus]
         (924 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

27926                                                                  91   3e-18
27299                                                                  40   0.003
24977                                                                  32   1.1  
>27926
          Length = 428

 Score = 90.5 bits (223), Expect = 3e-18,   Method: Composition-based stats.
 Identities = 45/105 (42%), Positives = 69/105 (65%)
 Frame = -3

Query: 180 FEQLKMAVTNLKRQANKKSEGSLAYVKGGLSTFFEAQDALSAIHQKLEADGTEKVEGSMT 239
           FE LK  +  +KR+++++SEG +  V+  L+   +  D+L+  +QK  +D    + G+  
Sbjct: 318 FEDLKAGLDYMKRRSSQRSEGPITVVRSNLTPILDCLDSLTTTYQKFASD---DIRGNCM 148

Query: 240 QKLENVLNRASNTADTLFQEVLGRKDKADSTRNALNVLQRFKFLF 284
                +L +A + AD LF+EVLGRKDKADSTRNAL+VL +F+FLF
Sbjct: 147 DSYAVLLMQAKSCADGLFREVLGRKDKADSTRNALSVLTKFRFLF 13

 Score = 33.5 bits (75), Expect = 0.42,   Method: Composition-based stats.
 Identities = 13/32 (40%), Positives = 19/32 (59%)
 Frame = -1

Query: 157 SADFTSENFSAAWYLIENHSTTSFEQLKMAVT 188
           S + + ENF+  WYL+ENH   S    ++A T
Sbjct: 386 SGNMSLENFAPGWYLLENHHNASLRT*RLAWT 291
>27299
          Length = 864

 Score = 40.4 bits (93), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 22/72 (30%), Positives = 38/72 (52%), Gaps = 2/72 (2%)
 Frame = -3

Query: 5   RQPPLVTGISPNEGI--PWTKVTIRGENLGTGPTDLIGLTICGHNCLLTAEWMSASKIVC 62
           R  P+VT + PN       T++ + G+NLG G +D++   +CG + L T ++ S ++I  
Sbjct: 850 RDIPIVTNLIPNMATVHGGTRLCVEGKNLGLGKSDIMEFMLCGSDLLDTIDFESETRIYV 671

Query: 63  RVGQAKNDKGDI 74
                   KGD+
Sbjct: 670 TTKPNTPGKGDL 635
>24977
          Length = 623

 Score = 32.0 bits (71), Expect = 1.1,   Method: Composition-based stats.
 Identities = 19/67 (28%), Positives = 34/67 (50%)
 Frame = -2

Query: 805 NIIAVHAEVFTISKELVPRVLARVVEAVSEELSRLMQCVSSFSRNGALQARLEICALRDT 864
           + + V   +  ISK + PRV + + + +++ L+RL  CV S S +G     +  C L  +
Sbjct: 433 SFVRVAIYIILISKVIEPRVTSHIWKLLTKPLARL*PCVRSESSDGLSNITILACKLSTS 254

Query: 865 VAIYLTS 871
            A  + S
Sbjct: 253 AASLMRS 233
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31981562|ref|NP_035229.2| pyruvate kinase, muscle
[Mus musculus]
         (531 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

21749                                                                  89   3e-18
07523                                                                  31   1.3  
>21749
          Length = 352

 Score = 89.4 bits (220), Expect = 3e-18,   Method: Composition-based stats.
 Identities = 44/99 (44%), Positives = 60/99 (60%)
 Frame = +3

Query: 24  DTFLEHMCRLDIDSAPITARNTGIICTIGPASRSVEMLKEMIKSGMNVARLNFSHGTHEY 83
           D+ L  +C LDID      R T +ICTIGPA   ++ +++MI+ GMN+ RLN +H T EY
Sbjct: 6   DSRLAQICSLDIDKGIRPFRMTSVICTIGPACDDIDTIEQMIQGGMNICRLNMAHNTLEY 185

Query: 84  HAETIKNVREATESFASDPILYRPVAVALDTKGPEIRTG 122
           H +TI N+REA     S      PVA+A++  G  IR G
Sbjct: 186 HLQTIHNIREAVHKTNSP----SPVAIAVEIAGQGIRLG 290
>07523
          Length = 1299

 Score = 30.8 bits (68), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 15/45 (33%), Positives = 26/45 (57%), Gaps = 4/45 (8%)
 Frame = +2

Query: 380  LIAREAEAAIYHLQLFEELRRLAPITSD----PTEAAAVGAVEAS 420
             +A++ E  I+  Q+F  LRRL P+T+     P  A+++G +  S
Sbjct: 1082 FVAQKIEVLIFSKQVFSRLRRLKPLTAHYEVCPKVASSLGWIPIS 1216
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|37700232|ref|NP_032730.1| nucleoside-diphosphate
kinase 1 [Mus musculus]
         (152 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

32935                                                                  87   3e-18
02656                                                                  82   8e-17
02733                                                                  70   5e-13
31902                                                                  28   1.0  
14087                                                                  28   1.3  
>32935
          Length = 1188

 Score = 86.7 bits (213), Expect = 3e-18,   Method: Compositional matrix adjust.
 Identities = 47/136 (34%), Positives = 75/136 (55%), Gaps = 3/136 (2%)
 Frame = +2

Query: 2   ANSERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLVGLKFLQASEDLLKEHYTDLKDRPFF 61
           +  ERT   IKPD V++  +G+++ +  QKGF +  L+  +   +   E Y + + +PF 
Sbjct: 269 SKRERTLGLIKPDAVEK--LGQVLDKILQKGFLISRLRMCKLDRNTALEFYQEHRSKPFL 442

Query: 62  TGLVKYMHSGPVVAMVWEGLNVVKTGRVMLGETNPADSK---PGTIRGDFCIQVGRNIIH 118
             L+ Y+ SGPVVA    G N V   R  +G T+P+ ++   P +IR  +   V  N +H
Sbjct: 443 NALLDYVTSGPVVAFEIVGENAVGAWREAIGPTDPSLARKEAPTSIRAQYGTDVTCNAVH 622

Query: 119 GSDSVKSAEKEISLWF 134
           GSDS  SA +E+  +F
Sbjct: 623 GSDSPGSAAREVEFFF 670

 Score = 37.4 bits (85), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 32/142 (22%), Positives = 61/142 (42%), Gaps = 13/142 (9%)
 Frame = +1

Query: 7   TFIAIKPDGVQRGLVGEIIKRFEQKGFRLVGLKFLQA----SEDLLKEHYTDLKDRPFFT 62
           T   IKP   + G+ G+II    + GFR+   +        +E+ L+ +   + + P   
Sbjct: 718 TCCIIKPSAFKAGVAGKIINAITEAGFRVGSAEMFTLEKANAEEFLEVYKGVVHEYP--- 888

Query: 63  GLVKYMHSGPVVAMVWEGLN------VVKTGRVMLGETNPADS---KPGTIRGDFCIQVG 113
            +V  + SGP +A+   G +      +    R + G  +P  +   +P T+R  F     
Sbjct: 889 AMVTELTSGPCLALEIVGGSGTNASLLAPAFRELAGPVDPEIARHLRPRTLRAMFGTDKI 1068

Query: 114 RNIIHGSDSVKSAEKEISLWFQ 135
           +N +H +D       E+  +F+
Sbjct: 1069KNAVHCTDLPDDGPLEVEYFFK 1134
>02656
          Length = 2642

 Score = 82.4 bits (202), Expect = 8e-17,   Method: Compositional matrix adjust.
 Identities = 46/133 (34%), Positives = 70/133 (52%), Gaps = 3/133 (2%)
 Frame = +3

Query: 5    ERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLVGLKFLQASEDLLKEHYTDLKDRPFFTGL 64
            E+T   IKPDG   G    II++  Q GFR+   K    + D+ +  Y D KD+ ++  L
Sbjct: 1074 EQTVAMIKPDGY--GTKDAIIEKIHQAGFRIAARKETTITRDIAESFYDDQKDKDYYESL 1247

Query: 65   VKYMHSGPVVAMVWEGLNVVKTGRVMLGETNPADSK---PGTIRGDFCIQVGRNIIHGSD 121
            V++M SGP + MV      V   R  +G T+P  +K   P ++R  F   V +N +HG+ 
Sbjct: 1248 VEHMTSGPTMFMVLSREGAVDGWREEIGPTDPTKAKEQNPNSLRAQFGTDVLQNAVHGAS 1427

Query: 122  SVKSAEKEISLWF 134
            S + A+K+I   F
Sbjct: 1428 SSEEAKKKIKAVF 1466

 Score = 68.9 bits (167), Expect = 7e-13,   Method: Compositional matrix adjust.
 Identities = 45/135 (33%), Positives = 70/135 (51%), Gaps = 7/135 (5%)
 Frame = +3

Query: 7   TFIAIKPDGVQRGLVGEIIKRFEQKGFRLVGLKFLQASEDLLKEHYTDLKDRPFFTGLVK 66
           T   IKP+ V  G V EI+   + +G  +   +  Q +ED  +E Y+ L+   +F  LV 
Sbjct: 219 TVAIIKPNVVANGKVDEILAEMKARGINVKAQEERQLTEDEAREFYSHLQGEEYFEDLVA 398

Query: 67  YMHSGPVVAMV----WEGLNVVKTGRVMLGETNPADSK---PGTIRGDFCIQVGRNIIHG 119
           +M SGP   +V     E  +VVK  R MLG     D+K   P ++R  +      N +HG
Sbjct: 399 FMASGPSHVLVLTEGQEDDSVVKDWRDMLGPPTVEDAKEQAPESLRARYGQGGLMNAVHG 578

Query: 120 SDSVKSAEKEISLWF 134
           SDS ++A +E++ +F
Sbjct: 579 SDSKETAARELAFFF 623

 Score = 68.9 bits (167), Expect = 8e-13,   Method: Compositional matrix adjust.
 Identities = 41/140 (29%), Positives = 75/140 (53%), Gaps = 4/140 (2%)
 Frame = +3

Query: 5   ERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLVGLKFLQASEDLLKEHYTDLKDRPFFTGL 64
           +RT   I+PD         I+++ ++ GF++   K +  +++  +E Y +   +P++  L
Sbjct: 669 QRTLALIRPDAFANNKDA-ILEKIKEAGFQIALHKEVSLTKEQAEEFYKEHAGQPYYDEL 845

Query: 65  VKYMHSGPVVAMVWEGLNVVKTGRVMLGETNPADSK---PGTIRGDFCI-QVGRNIIHGS 120
              M SGP++A+     + V+  R MLG T+  ++K   P  +R  F +     N +HGS
Sbjct: 846 TDRMSSGPLLALGLAREDAVENWREMLGPTDVEEAKTAAPDCLRAQFAVDSTAINQLHGS 1025

Query: 121 DSVKSAEKEISLWFQPEELV 140
           DS +SA+KE+  +F  E+ V
Sbjct: 1026DSTQSAKKELEFFFPVEQTV 1085
>02733
          Length = 853

 Score = 69.7 bits (169), Expect = 5e-13,   Method: Compositional matrix adjust.
 Identities = 36/112 (32%), Positives = 59/112 (52%), Gaps = 3/112 (2%)
 Frame = -1

Query: 26  KRFEQKGFRLVGLKFLQASEDLLKEHYTDLKDRPFFTGLVKYMHSGPVVAMVWEGLNVVK 85
           ++  Q GFR+   K    + D+ +  Y D KD+ ++  LV++M SGP + MV      V 
Sbjct: 748 RKIHQAGFRIAARKETTITRDIAESFYDDQKDKDYYESLVEHMTSGPTMFMVLSREGAVD 569

Query: 86  TGRVMLGETNPADSK---PGTIRGDFCIQVGRNIIHGSDSVKSAEKEISLWF 134
             R  +G T+P  +K   P ++R  F   V +N +HG+ S + A+K+I   F
Sbjct: 568 GWREEIGPTDPTKAKEQNPNSLRAQFGTDVLQNAVHGASSSEEAKKKIKAVF 413
>31902
          Length = 546

 Score = 28.5 bits (62), Expect = 1.0,   Method: Compositional matrix adjust.
 Identities = 14/38 (36%), Positives = 22/38 (57%), Gaps = 3/38 (7%)
 Frame = +1

Query: 88  RVMLGETNPADSK---PGTIRGDFCIQVGRNIIHGSDS 122
           R  +G T+P+ ++   P +IR  +   V  N +HGSDS
Sbjct: 391 REAIGPTDPSLARKEAPTSIRAQYGTDVTCNAVHGSDS 504
>14087
          Length = 2025

 Score = 28.5 bits (62), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 14/41 (34%), Positives = 22/41 (53%)
 Frame = +2

Query: 60  FFTGLVKYMHSGPVVAMVWEGLNVVKTGRVMLGETNPADSK 100
           ++  LV++M SGP + MV      V   R  +G T+P  S+
Sbjct: 2   YYESLVEHMTSGPTMFMVLSREGAVDGWREEIGPTDPTKSQ 124
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6671561|ref|NP_031484.1| adaptor protein complex
AP-2, alpha 1 subunit isoform a [Mus musculus]
         (977 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

35332                                                                  91   3e-18
32748                                                                  33   0.62 
03307                                                                  33   0.83 
>35332
          Length = 396

 Score = 90.5 bits (223), Expect = 3e-18,   Method: Composition-based stats.
 Identities = 43/50 (86%), Positives = 47/50 (94%)
 Frame = -1

Query: 1   MPAVSKGDGMRGLAVFISDIRNCKSKEAEIKRINKELANIRSKFKGDKAL 50
           MPA +KGDGMRGLAVFISDIRNCKSKEAE+KRINKELANIRSKFKG + +
Sbjct: 285 MPA-AKGDGMRGLAVFISDIRNCKSKEAEVKRINKELANIRSKFKGKRTV 139
>32748
          Length = 429

 Score = 33.1 bits (74), Expect = 0.62,   Method: Compositional matrix adjust.
 Identities = 42/169 (24%), Positives = 74/169 (43%), Gaps = 8/169 (4%)
 Frame = -3

Query: 190 ARVVHLLNDQHMGVVTAAVSLITCLCKKNPDDFKTCISLAVSRLSRIVSSASTDLQDYTY 249
           +R    L D   GV +AAV++I  L +KNP ++   +SLA      + +S +        
Sbjct: 418 SRXKEKLEDPDPGVQSAAVNVICELARKNPKNY---LSLAPLFFKLMTTSTNN------- 269

Query: 250 YFVPAPWLSVKLLRLLQCYPPPEDAAVKGRLVECLETVLNKAQEPPKSKKVQHSNAKNAI 309
                 W+ +K+++L     P E    K +L+E L  ++             HS +  ++
Sbjct: 268 ------WVLIKIIKLFGALTPLEPRLGK-KLIEPLTNLI-------------HSTSAMSL 149

Query: 310 LFETISLIIHY-----DSEPN--LLVRACNQ-LGQFLQHRETNLRYLAL 350
           L+E I+ +I          PN    ++ C Q L   ++  + NL+YL L
Sbjct: 148 LYECINTVIAVLVSISSGIPNHSASIQLCVQKLRILIEDSDQNLKYLGL 2
>03307
          Length = 1328

 Score = 32.7 bits (73), Expect = 0.83,   Method: Compositional matrix adjust.
 Identities = 17/53 (32%), Positives = 27/53 (50%), Gaps = 4/53 (7%)
 Frame = -2

Query: 750 KNSGVLFEN----QLLQIGVKSEFRQNLGRMYLFYGNKTSVQFQNFLPTVVHP 798
           +NSG   +N      ++ GV+  FRQ   R YL+  N   + F++F   V+ P
Sbjct: 958 RNSGKCSDN*TXPGAIKHGVRPNFRQGNSRGYLYRTNXRDIMFRSFASDVIPP 800
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|24429570|ref|NP_082474.1| exportin 5 [Mus musculus]
         (1204 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

25569                                                                  91   4e-18
01462                                                                  32   1.1  
27334                                                                  31   3.6  
>25569
          Length = 432

 Score = 90.5 bits (223), Expect = 4e-18,   Method: Compositional matrix adjust.
 Identities = 44/114 (38%), Positives = 73/114 (64%)
 Frame = +2

Query: 868 LASQLLGSAFVNLNNIPDFRLRSMLRVFVKPLVLFCPSEHYETLISPILGPLFTYLHMRL 927
           L   L+ S F N+ ++PD+RL+ ++R F+KP V+ CP+++Y +   P+L  L   +  RL
Sbjct: 2   LGQVLVTSVFSNVQHLPDYRLKPVIRAFIKPYVMNCPAKYYASSAVPVLVALCPAMFQRL 181

Query: 928 SQKWHVINQRSILCGEDEIAEDNPESQEMLEEQLVRMLTREAMDLIMACCVSKK 981
           S KW  I+QR     ++ + ED  ESQE+LE+QL R LTRE ++L+    ++++
Sbjct: 182 SAKWVHIDQRV----DEGLDEDETESQEVLEDQLTRQLTREYLELLGTVLIARQ 331
>01462
          Length = 995

 Score = 32.3 bits (72), Expect = 1.1,   Method: Composition-based stats.
 Identities = 14/41 (34%), Positives = 19/41 (46%)
 Frame = +3

Query: 479 VNSCSTAGTGEGGFCSIFSPSYVQWEAMTFFLESVINQMFR 519
           ++ C   G   GG    FSP  + W  +  FLE   +QM R
Sbjct: 78  LDQCGRTGRYRGGDGQTFSPRLLNWPGLCRFLEVEFSQMLR 200
>27334
          Length = 603

 Score = 30.8 bits (68), Expect = 3.6,   Method: Composition-based stats.
 Identities = 19/54 (35%), Positives = 28/54 (51%)
 Frame = +3

Query: 716 LNRARMSFCVYSILGVMRRTSWPSDLEEAKAGGFVVGYTPSGNPIFRNPCTEQI 769
           LNR+  S CV ++LGV+     P      +A   VVG+   G   FR P T+++
Sbjct: 135 LNRSDWSICVTALLGVLSTHGDP-----CRAEWLVVGWR-GGQFFFRPPLTDEV 278
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31980859|ref|NP_059098.2| PAK-interacting exchange
factor beta isoform c [Mus musculus]
         (646 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

27166                                                                  89   4e-18
12324                                                                  60   4e-09
01494                                                                  58   1e-08
29687                                                                  57   2e-08
11641                                                                  53   3e-07
16716                                                                  53   4e-07
17286                                                                  47   2e-05
20131                                                                  47   2e-05
13641                                                                  45   1e-04
18050                                                                  43   3e-04
26032                                                                  43   3e-04
30482                                                                  43   4e-04
27252                                                                  42   8e-04
15115                                                                  37   0.021
11228                                                                  35   0.074
21187                                                                  35   0.092
19469                                                                  35   0.12 
30740                                                                  34   0.18 
31183                                                                  34   0.19 
36643                                                                  34   0.23 
29636                                                                  33   0.28 
38272                                                                  32   0.59 
33143                                                                  32   0.95 
08480                                                                  31   1.2  
13664                                                                  29   5.1  
21573                                                                  29   7.5  
11780                                                                  28   9.7  
>27166
          Length = 405

 Score = 89.4 bits (220), Expect = 4e-18,   Method: Compositional matrix adjust.
 Identities = 49/100 (49%), Positives = 70/100 (70%)
 Frame = -2

Query: 531 EDAQILKVIEAYCTSAKTRQTLNSSSRKESAPQVLLPEEEKIIVEETKSNGQTVIEEKSL 590
           EDA IL+VIEAYC S KTR T+NS     + P +L+PE+EKI+           +EEK+L
Sbjct: 350 EDAFILQVIEAYCNSTKTRHTVNSYVL--NHPSLLVPEDEKIL-------NTDDLEEKTL 198

Query: 591 VDTVYALKDEVQELRQDNKKMKKSLEEEQRARKDLEKLVR 630
           VDTVY+LKD+V++L Q+ +++++ L+EE+RAR  LE   R
Sbjct: 197 VDTVYSLKDKVRQLEQEQRRLRQDLDEERRARLQLETTFR 78
>12324
          Length = 946

 Score = 59.7 bits (143), Expect = 4e-09,   Method: Compositional matrix adjust.
 Identities = 25/50 (50%), Positives = 35/50 (70%)
 Frame = +3

Query: 11  VRAKFNFQQTNEDELSFSKGDVIHVTRVEEGGWWEGTHNGRTGWFPSNYV 60
           V A ++++   +DEL+FS+  VI+V R  + GWWEG  +G TG FPSNYV
Sbjct: 696 VVAIYDYEAEKDDELTFSENSVIYVIRKNDDGWWEGVMDGVTGLFPSNYV 845
>01494
          Length = 2122

 Score = 57.8 bits (138), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 24/63 (38%), Positives = 39/63 (61%), Gaps = 1/63 (1%)
 Frame = +3

Query: 3   DNTNSQLVVRAKFNFQQTNEDELSFSKGDVIHVTRVEEGGWWEGTHNGRT-GWFPSNYVR 61
           ++  ++L V+A  ++    +DELSF KG +I     ++GGWW G +  +   WFPSN+V 
Sbjct: 288 NDFTTKLRVKALHDYNANRDDELSFCKGAIITNVSRQDGGWWRGDYGAKKQHWFPSNFVE 467

Query: 62  EIK 64
           EI+
Sbjct: 468 EIE 476
>29687
          Length = 434

 Score = 57.0 bits (136), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 26/62 (41%), Positives = 38/62 (61%), Gaps = 1/62 (1%)
 Frame = -2

Query: 3   DNTNSQLVVRAKFNFQQTNEDELSFSKGDVIHVTRVEEGGWWEGTHNGRT-GWFPSNYVR 61
           ++  ++L V+A  ++    EDELSF KG +I     ++GGWW G +  +   WFPSNYV 
Sbjct: 316 NDFTTKLRVKALHDYNAKREDELSFCKGAIITNVSRQDGGWWRGDYGTKKQHWFPSNYVE 137

Query: 62  EI 63
           EI
Sbjct: 136 EI 131
>11641
          Length = 2509

 Score = 53.1 bits (126), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 31/102 (30%), Positives = 51/102 (50%), Gaps = 5/102 (4%)
 Frame = -1

Query: 183  YLAYCANHPSAVSVLTEHSE--DLGEFMETK---GASSPGILVLTTGLSKPFMRLDKYPT 237
            Y  YC +H   +SV+ ++ E  +  ++   K         I  +   L KP  R+ KYP 
Sbjct: 2500 YAPYCRHHDDVISVMDKYHELPEACQYFAAKVEEMRRRTNIFDVEAMLIKPVQRILKYPL 2321

Query: 238  LLKELERHMEDYHPDRQDIQKSMTAFKNLSAQCQEVRKRKEL 279
            LL EL +  ED HPD+  I  ++ A  +++    E ++RK+L
Sbjct: 2320 LLNELFKSTEDDHPDKTAIGNAIRAMTDVATAINEYKRRKDL 2195

 Score = 32.7 bits (73), Expect = 0.47,   Method: Compositional matrix adjust.
 Identities = 17/55 (30%), Positives = 30/55 (54%), Gaps = 4/55 (7%)
 Frame = -1

Query: 13  AKFNFQQTNEDELSFSKGDVIHV-TRVEEGG---WWEGTHNGRTGWFPSNYVREI 63
           A F FQ  + +E++   G V+ V  R +  G   WW    +G  G+ P++Y+R++
Sbjct: 823 ADFPFQARSSNEVTLFAGQVVVVLNRQDLDGNTEWWLVDADGYQGYAPASYLRKM 659
>16716
          Length = 934

 Score = 52.8 bits (125), Expect = 4e-07,   Method: Compositional matrix adjust.
 Identities = 20/48 (41%), Positives = 32/48 (66%)
 Frame = -1

Query: 13  AKFNFQQTNEDELSFSKGDVIHVTRVEEGGWWEGTHNGRTGWFPSNYV 60
           A +++Q  ++DEL+F   DVI    + + GWW G+ +G+ G FP+NYV
Sbjct: 457 ALYDYQAADDDELTFDPDDVITDIEMIDDGWWRGSCHGKNGLFPANYV 314
>17286
          Length = 489

 Score = 47.4 bits (111), Expect = 2e-05,   Method: Composition-based stats.
 Identities = 21/58 (36%), Positives = 35/58 (60%)
 Frame = +3

Query: 8  QLVVRAKFNFQQTNEDELSFSKGDVIHVTRVEEGGWWEGTHNGRTGWFPSNYVREIKP 65
          Q   RA ++F   ++ EL F +GD+I +    +  W+EG+ +G+ G+FP NYV  + P
Sbjct: 21 QPCARAIYDFLPESDGELGFQEGDMITLISQVDENWFEGSVHGKVGYFPINYVEVVVP 194
>20131
          Length = 574

 Score = 47.4 bits (111), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 24/58 (41%), Positives = 38/58 (65%), Gaps = 2/58 (3%)
 Frame = -2

Query: 13  AKFNFQQTNEDELSFSKGDVIHVTRVEEGGWWEGTHNGRTGWFPSNYVR--EIKPSEK 68
           A +++      +L+F++GD+I VT+ +E  WW GT   +TG FPS YV+  EI+P +K
Sbjct: 468 AMYSYVSGETADLTFNEGDMILVTKKDED-WWTGTLGEKTGMFPSTYVKKVEIQPGQK 298

 Score = 44.7 bits (104), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 21/61 (34%), Positives = 31/61 (50%), Gaps = 5/61 (8%)
 Frame = -2

Query: 17  FQQTNEDELSFSKGDVIHVTRVEEGGWWEGTHNGR-----TGWFPSNYVREIKPSEKPVS 71
           +  T   +LS   G++IHV +    GWWEG    R      GWFP++YV+ +  S    +
Sbjct: 258 YTATGNGQLSLEPGNLIHVRQKSPRGWWEGELQARGQRKKIGWFPADYVKPLGSSSARST 79

Query: 72  P 72
           P
Sbjct: 78  P 76
>13641
          Length = 2081

 Score = 44.7 bits (104), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 21/66 (31%), Positives = 34/66 (51%), Gaps = 11/66 (16%)
 Frame = +2

Query: 8   QLVVRAKFNFQQTNEDE-------LSFSKGDVIHVTRVEEGGWWEGTHNG----RTGWFP 56
           ++VV+A F+F    +D        LSF +GD++H+   E+  WW+   +G    R G  P
Sbjct: 149 EMVVKAMFSFNSKLDDNIPCKEAGLSFQQGDILHIVNQEDAIWWQAYKHGDAKKRAGLIP 328

Query: 57  SNYVRE 62
           S +  E
Sbjct: 329 SRHYHE 346
>18050
          Length = 448

 Score = 43.1 bits (100), Expect = 3e-04,   Method: Composition-based stats.
 Identities = 20/58 (34%), Positives = 32/58 (55%), Gaps = 2/58 (3%)
 Frame = +3

Query: 11 VRAKFNFQQTNEDELSFSKGDVIHVTRVEEGGWWEG--THNGRTGWFPSNYVREIKPS 66
          V AK +++    D L    GDV++V+R    GW++G    +G  GWFP +Y  E+  +
Sbjct: 24 VIAKHSYESDEPDVLQLELGDVVNVSRKLPDGWYQGERIRDGAVGWFPGSYTEELNSA 197
>26032
          Length = 465

 Score = 43.1 bits (100), Expect = 3e-04,   Method: Composition-based stats.
 Identities = 19/56 (33%), Positives = 31/56 (55%)
 Frame = +2

Query: 16 NFQQTNEDELSFSKGDVIHVTRVEEGGWWEGTHNGRTGWFPSNYVREIKPSEKPVS 71
          +F++ ++DEL F K D+I +   ++   W G  NG  GWFP+ +V  +    K  S
Sbjct: 29 DFERHDDDELGFRKNDIITLISQKDEHCWIGELNGLRGWFPAKFVEVLDERSKNYS 196
>30482
          Length = 610

 Score = 42.7 bits (99), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 27/66 (40%), Positives = 39/66 (59%), Gaps = 5/66 (7%)
 Frame = +3

Query: 12  RAKFNFQQTNEDELSFSKGDVIHVTRV-EEGG---WWEG-THNGRTGWFPSNYVREIKPS 66
           RA F F+  +EDEL+ + GD I V  V  E G   W++G T +G+ GWFP  Y    +P+
Sbjct: 132 RALFPFESRSEDELNINTGDDIWVWDVPSEPGMEEWFKGETKDGKVGWFPQAYA---EPN 302

Query: 67  EKPVSP 72
            +P +P
Sbjct: 303 PEPAAP 320
>27252
          Length = 378

 Score = 42.0 bits (97), Expect = 8e-04,   Method: Compositional matrix adjust.
 Identities = 19/48 (39%), Positives = 27/48 (56%)
 Frame = +2

Query: 24  ELSFSKGDVIHVTRVEEGGWWEGTHNGRTGWFPSNYVREIKPSEKPVS 71
           +L   +G+ I V  +   G WEG  NGRTG FP  +V  +   E+PV+
Sbjct: 170 QLKLKQGETIKVLAINIDGQWEGEINGRTGKFPFTHVEFLSEDEQPVT 313
>15115
          Length = 443

 Score = 37.4 bits (85), Expect = 0.021,   Method: Composition-based stats.
 Identities = 17/45 (37%), Positives = 30/45 (66%), Gaps = 2/45 (4%)
 Frame = -2

Query: 18  QQTNEDELSFSKGDVI-HVTRVEEGGWWEG-THNGRTGWFPSNYV 60
           Q  ++ E++F   D+I ++ +++EG WW+G   +G  G FP+NYV
Sbjct: 430 QAGDDTEITFDPDDIITNIDQIDEG-WWQGFAPDGSYGMFPANYV 299
>11228
          Length = 2155

 Score = 35.4 bits (80), Expect = 0.074,   Method: Compositional matrix adjust.
 Identities = 20/55 (36%), Positives = 30/55 (54%), Gaps = 2/55 (3%)
 Frame = -2

Query: 18   QQTNEDELSFSKGDVIHVTRVEEGGW-WEGTHNGR-TGWFPSNYVREIKPSEKPV 70
            + T+ DELSF KGDV  V    E GW W      + +G  P+ +V+++    +PV
Sbjct: 1641 KATDSDELSFCKGDVFVVQNEMEDGWLWVTCERTKESGLVPAPFVKDLDGDYEPV 1477
>21187
          Length = 1206

 Score = 35.0 bits (79), Expect = 0.092,   Method: Compositional matrix adjust.
 Identities = 14/42 (33%), Positives = 23/42 (54%), Gaps = 3/42 (7%)
 Frame = +2

Query: 25  LSFSKGDVIHVTRVEEGG---WWEGTHNGRTGWFPSNYVREI 63
           L+ ++GD++ +     G     W G  NGR G+FP  +V+E 
Sbjct: 173 LTLNRGDIVEIKSKSAGNRPDLWGGEVNGRKGYFPKAFVKEF 298
>19469
          Length = 428

 Score = 34.7 bits (78), Expect = 0.12,   Method: Compositional matrix adjust.
 Identities = 17/56 (30%), Positives = 28/56 (50%), Gaps = 3/56 (5%)
 Frame = -1

Query: 9   LVVRAKFNFQQTNEDELSFSKGDVIHVTRVEEG---GWWEGTHNGRTGWFPSNYVR 61
            + +A ++      DEL+F +GDVI +   +     GWW  +  GR G  P N ++
Sbjct: 365 FLAKALYDNIAETPDELAFRRGDVITILEQDTAGLDGWWLCSLRGRQGIAPGNRLK 198
>30740
          Length = 488

 Score = 34.3 bits (77), Expect = 0.18,   Method: Compositional matrix adjust.
 Identities = 14/42 (33%), Positives = 24/42 (57%), Gaps = 1/42 (2%)
 Frame = +2

Query: 13  AKFNFQQTNEDELSFSKGDVIHVTRVEEGGWWEG-THNGRTG 53
            K++F   + ++L FSKGD++ +   +E  WW     +GR G
Sbjct: 197 GKYDFSGRDPEDLPFSKGDILELISKDEEEWWTARDKHGRVG 322
>31183
          Length = 923

 Score = 33.9 bits (76), Expect = 0.19,   Method: Compositional matrix adjust.
 Identities = 14/30 (46%), Positives = 20/30 (66%)
 Frame = +1

Query: 31 DVIHVTRVEEGGWWEGTHNGRTGWFPSNYV 60
          DVI    + + GWW G+ +G+ G FP+NYV
Sbjct: 4  DVITDIEMIDDGWWRGSCHGKNGLFPANYV 93
>36643
          Length = 601

 Score = 33.9 bits (76), Expect = 0.23,   Method: Composition-based stats.
 Identities = 23/78 (29%), Positives = 34/78 (43%), Gaps = 12/78 (15%)
 Frame = +1

Query: 8   QLVVRAKFNFQQTNEDELSFSKGDVIHVTRVEEG----GWWEGTHNGRTGWFPSNYV--- 60
            +V +  F+F    E+ELSFS G  + +   E      GW   +  GR G  P NY+   
Sbjct: 187 HVVAQTLFSFTGQGEEELSFSAGQQLILAPKEVQPQVRGWLLASVGGRKGLVPYNYIKIL 366

Query: 61  -----REIKPSEKPVSPK 73
                R+   S  P +P+
Sbjct: 367 GKRRGRQQNASASPTAPQ 420
>29636
          Length = 354

 Score = 33.5 bits (75), Expect = 0.28,   Method: Composition-based stats.
 Identities = 19/68 (27%), Positives = 31/68 (45%), Gaps = 12/68 (17%)
 Frame = +1

Query: 11  VRAKFNFQQTN-------EDELSFSKGDVIHVTRVEEGGWWEGTHNGR-----TGWFPSN 58
           +RA FN+   +       E  +SF KGD++H  ++ +  WW+    G       G  PS 
Sbjct: 76  LRALFNYDPEDDPYIPCRELGISFLKGDILHAIQLSDSNWWQAHREGEDAHMLAGLIPSK 255

Query: 59  YVREIKPS 66
             +E + S
Sbjct: 256 AFQEQRES 279
>38272
          Length = 749

 Score = 32.3 bits (72), Expect = 0.59,   Method: Compositional matrix adjust.
 Identities = 16/64 (25%), Positives = 31/64 (48%)
 Frame = +2

Query: 181 TLYLAYCANHPSAVSVLTEHSEDLGEFMETKGASSPGILVLTTGLSKPFMRLDKYPTLLK 240
           T+Y  +C+N P +  ++ EH +   +  +  G  +     L+  +  P  R+ KY  L+ 
Sbjct: 5   TMYYYFCSNKPLSEFIVNEHYQYFDQIRQKLGHRND----LSALIITPVQRITKYVLLIN 172

Query: 241 ELER 244
           E+ R
Sbjct: 173 EILR 184
>33143
          Length = 1469

 Score = 31.6 bits (70), Expect = 0.95,   Method: Compositional matrix adjust.
 Identities = 18/52 (34%), Positives = 26/52 (50%), Gaps = 3/52 (5%)
 Frame = -2

Query: 23  DELSFSKGDVIHVTRV---EEGGWWEGTHNGRTGWFPSNYVREIKPSEKPVS 71
           DE+S   GD + V  +   E   WW G      G+FP++ V  I+  + PVS
Sbjct: 394 DEISLQVGDFVSVIDMPSSEGTKWWRGKKGFEVGFFPADCVEVIR-DKVPVS 242
>08480
          Length = 698

 Score = 31.2 bits (69), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 13/42 (30%), Positives = 23/42 (54%), Gaps = 5/42 (11%)
 Frame = -1

Query: 9   LVVRAKFNFQQTNEDELS-----FSKGDVIHVTRVEEGGWWE 45
           + VRA F+++ + +  L      F  GD++HVT   +  WW+
Sbjct: 452 MFVRALFDYEPSKDSGLPSRGLWFHYGDILHVTNASDDEWWQ 327
>13664
          Length = 507

 Score = 29.3 bits (64), Expect = 5.1,   Method: Compositional matrix adjust.
 Identities = 12/36 (33%), Positives = 19/36 (52%)
 Frame = +2

Query: 11  VRAKFNFQQTNEDELSFSKGDVIHVTRVEEGGWWEG 46
           V A ++++    DEL+   GDVI +   +   WW G
Sbjct: 371 VVALYDYKAQRSDELTILSGDVIMLLHKDSESWWMG 478
>21573
          Length = 1471

 Score = 28.9 bits (63), Expect = 7.5,   Method: Compositional matrix adjust.
 Identities = 12/35 (34%), Positives = 22/35 (62%)
 Frame = -2

Query: 381 SCTSQQDLHEWVEHLQKQTKVTSVSNPTIKPHSVP 415
           SC++Q+DL EW+ H+     +    +P+I+P + P
Sbjct: 207 SCSNQKDLDEWMGHIDFTG*IHLSIHPSIQPSTSP 103
>11780
          Length = 1713

 Score = 28.5 bits (62), Expect = 9.7,   Method: Compositional matrix adjust.
 Identities = 14/37 (37%), Positives = 19/37 (51%), Gaps = 2/37 (5%)
 Frame = +3

Query: 27  FSKGDVIHVTRVEEGGWWEGT--HNGRTGWFPSNYVR 61
           F KGD++ + R      W      NGR G  P+NYV+
Sbjct: 111 FQKGDLLVIRRATSDRMWYKACDSNGREGMIPANYVQ 221
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|7305061|ref|NP_038930.1| FK506 binding protein 3,
25kDa [Mus musculus]
         (224 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

00011                                                                  71   5e-18
00162                                                                  63   9e-11
00888                                                                  47   7e-06
37162                                                                  39   0.001
>00011
          Length = 1711

 Score = 70.9 bits (172), Expect(2) = 5e-18,   Method: Compositional matrix adjust.
 Identities = 31/62 (50%), Positives = 44/62 (70%)
 Frame = +1

Query: 160 KPLSFKVGVGKVIRGWDEALLTMSKGEKARLEIEPEWAYGKKGQPDAKIPPNTKLIFEVE 219
           + + FK+G G+VI+ WDE ++ MS GE+A L   P++AYG+ G  D  IPPN  LIF+VE
Sbjct: 235 QAICFKIGTGQVIKAWDEGVMKMSVGERATLTASPDYAYGRNGIGDI-IPPNATLIFDVE 411

Query: 220 LV 221
           L+
Sbjct: 412 LL 417

 Score = 36.6 bits (83), Expect(2) = 5e-18,   Method: Compositional matrix adjust.
 Identities = 18/51 (35%), Positives = 27/51 (52%)
 Frame = +2

Query: 116 LKKGDKTNFPKKGDVVHCWYTGTLPDGTVFDTNIQTSSKKKKNAKPLSFKV 166
           + +GD + +PK GD V   YTGTL +G  FD++       +   KP   K+
Sbjct: 125 ITEGDGSTYPKAGDSVQVHYTGTLTNGKKFDSS-------RDRGKPFVLKL 256
>00162
          Length = 2322

 Score = 63.2 bits (152), Expect = 9e-11,   Method: Compositional matrix adjust.
 Identities = 35/96 (36%), Positives = 52/96 (54%), Gaps = 1/96 (1%)
 Frame = +2

Query: 126  KKGDVVHCWYTGTLP-DGTVFDTNIQTSSKKKKNAKPLSFKVGVGKVIRGWDEALLTMSK 184
            K G +V  +Y+GTL  +   FD+ ++         KP  FK+G G+VI+GWD  L+ M  
Sbjct: 1949 KPGHLVSVYYSGTLAKNNKRFDSCLK--------GKPFRFKLGRGEVIKGWDNGLIGMRV 2104

Query: 185  GEKARLEIEPEWAYGKKGQPDAKIPPNTKLIFEVEL 220
            G K ++ +     YG   Q    IPP + L+F+VEL
Sbjct: 2105 GGKRKITVPSSQGYGNSRQ--GPIPPGSTLVFDVEL 2206
>00888
          Length = 970

 Score = 47.0 bits (110), Expect = 7e-06,   Method: Compositional matrix adjust.
 Identities = 20/54 (37%), Positives = 34/54 (62%)
 Frame = -3

Query: 171 VIRGWDEALLTMSKGEKARLEIEPEWAYGKKGQPDAKIPPNTKLIFEVELVDID 224
           +I G + A L M KGE+ +L +  ++AYG++G     IP N  L++ VE+V+ +
Sbjct: 950 IIAGIELATLKMKKGERDQLTVASKYAYGEEGCXRFNIPSNATLVYNVEMVNFE 789
>37162
          Length = 601

 Score = 39.3 bits (90), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 26/77 (33%), Positives = 37/77 (48%), Gaps = 6/77 (7%)
 Frame = -2

Query: 126 KKGDVVHCWYTGTLPDGTVFDTNIQTSSKKKKNAKPLSFKVGVGKVIRGWDEALLTMSKG 185
           + GD V   YTG L  G VFD+++Q         +PL F +G  KVI GW+        G
Sbjct: 588 RDGDGVAVHYTGYLETGAVFDSSVQAGR------EPLEFLLGERKVIPGWEMGX*RNVCG 427

Query: 186 EKARLE------IEPEW 196
            KA+++        P+W
Sbjct: 426 RKAQVDHSSPSGJRPDW 376
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|21312564|ref|NP_082320.1| calponin 3, acidic [Mus
musculus]
         (330 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

03735                                                                  87   6e-18
04399                                                                  59   3e-09
20103                                                                  59   4e-09
34796                                                                  30   1.8  
09711                                                                  28   6.8  
02050                                                                  28   7.6  
>03735
          Length = 2383

 Score = 87.4 bits (215), Expect = 6e-18,   Method: Compositional matrix adjust.
 Identities = 62/209 (29%), Positives = 96/209 (45%), Gaps = 26/209 (12%)
 Frame = +2

Query: 6   KGPSYGLSAEVKNKIASKYDQQAEEDLRNWIEEVTG-----------LGIGTNFQLGLKD 54
           + P  G + + +NKI + +D    +    WI+  TG             +  NF   L+D
Sbjct: 215 RAPKAGSNRDAQNKIDASFDCDDAKKALYWIQAATGERVPITDSDNKAEVMNNFHQVLQD 394

Query: 55  GIILCELINK-LQPGSVKKVNESSLNWPQ--------------LENIGNFIKAIQAYGMK 99
           G +LC+L N  L P     +   +   PQ               E I  F   IQ +G+ 
Sbjct: 395 GFLLCKLANAFLPPDQQFDMRTRTFRPPQNQDGLKSNFESARERERIDLFNMKIQDFGVS 574

Query: 100 PHDIFEANDLFENGNMTQVQTTLVALAGLAKTKGFHTTIDIGVKYAEKQTRRFDEGKLKA 159
             D F+ + L+E  N+++V +T+       + +  +T   I  + +E   R F E KL+A
Sbjct: 575 EQDTFQTDCLYERTNLSKVISTIRVFGITVEAQPSYTGQKIWPRKSEANPRHFSEEKLRA 754

Query: 160 GQSVIGLQMGTNKCASQAGMTAYGTRRHL 188
            Q+VI LQ GTNK ASQAGM  +G +R +
Sbjct: 755 SQNVISLQYGTNKGASQAGMN-FGKKRMI 838

 Score = 28.1 bits (61), Expect = 5.7,   Method: Compositional matrix adjust.
 Identities = 15/27 (55%), Positives = 19/27 (70%)
 Frame = +2

Query: 241 STISLQMGTNKVASQKGMSVYGLGRQV 267
           + ISLQ GTNK ASQ GM+ +G  R +
Sbjct: 761 NVISLQYGTNKGASQAGMN-FGKKRMI 838
>04399
          Length = 1562

 Score = 58.5 bits (140), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 33/66 (50%), Positives = 45/66 (68%)
 Frame = -1

Query: 163  VIGLQMGTNKCASQAGMTAYGTRRHLYDPKMQTDKPFDQTTISLQMGTNKGASQAGMLAP 222
            VIGLQ G+NK ASQ GM+  G  RH+ D  ++      Q+ I+LQ G+N+GA+Q+GM + 
Sbjct: 1466 VIGLQAGSNKGASQXGMS-MGAVRHIADIPVEEMSAGSQSAINLQYGSNQGANQSGM-SY 1293

Query: 223  GTRRDI 228
            G RRDI
Sbjct: 1292 GGRRDI 1275

 Score = 58.5 bits (140), Expect = 4e-09,   Method: Compositional matrix adjust.
 Identities = 42/99 (42%), Positives = 55/99 (55%), Gaps = 1/99 (1%)
 Frame = -1

Query: 170  TNKCASQAGMTAYGTRRHLYDPKMQTDKPFDQTTISLQMGTNKGASQAGMLAPGTRRDIY 229
            +NK ASQAGM+  G  RH+ D +           I LQ G+NKGASQ GM + G  R I 
Sbjct: 1562 SNKGASQAGMS-MGAVRHIADIRADDASRESSGVIGLQAGSNKGASQXGM-SMGAVRHIA 1389

Query: 230  DQKL-TLQPVDNSTISLQMGTNKVASQKGMSVYGLGRQV 267
            D  +  +     S I+LQ G+N+ A+Q GMS YG  R +
Sbjct: 1388 DIPVEEMSAGSQSAINLQYGSNQGANQSGMS-YGGRRDI 1275
>20103
          Length = 484

 Score = 58.5 bits (140), Expect = 4e-09,   Method: Compositional matrix adjust.
 Identities = 31/102 (30%), Positives = 51/102 (50%), Gaps = 6/102 (5%)
 Frame = -2

Query: 30  EDLRNWIEEVTGLGIGTNFQLGLKDGIILCELINKLQPGSVKKVNESSLNWPQL------ 83
           E LR  IE    + +  N    L+DG++LC L N+++P SV  ++  S   P+L      
Sbjct: 306 EMLRQTIESRLKVTLPDNLAEALRDGVVLCHLANQIRPRSVASIHVPSPAVPKLTSAKCR 127

Query: 84  ENIGNFIKAIQAYGMKPHDIFEANDLFENGNMTQVQTTLVAL 125
            N+ NF+ A +  G+    +  A D+ E   + +V  T+ AL
Sbjct: 126 RNVENFLDACRKIGVDQEQVCVATDIMEERGVQRVAITVAAL 1
>34796
          Length = 620

 Score = 29.6 bits (65), Expect = 1.8,   Method: Compositional matrix adjust.
 Identities = 12/35 (34%), Positives = 21/35 (60%)
 Frame = +2

Query: 109 LFENGNMTQVQTTLVALAGLAKTKGFHTTIDIGVK 143
           LF   ++  V   +++L+GL  ++GF   IDI V+
Sbjct: 266 LFSGQHILHVTVAIMSLSGLPLSRGFSRKIDIAVR 370
>09711
          Length = 3041

 Score = 27.7 bits (60), Expect = 6.8,   Method: Compositional matrix adjust.
 Identities = 18/67 (26%), Positives = 34/67 (50%)
 Frame = +1

Query: 4   FNKGPSYGLSAEVKNKIASKYDQQAEEDLRNWIEEVTGLGIGTNFQLGLKDGIILCELIN 63
           FN  P+   + +V+ +   K + + E+  RNW+  +       +    L DG+I+ +L +
Sbjct: 781 FNNYPALD-TPQVEVEDVMKEESREEKTYRNWMNSLGVSPFVHHLYSDLYDGLIIFQLYD 957

Query: 64  KLQPGSV 70
            +QPG V
Sbjct: 958 YIQPGLV 978
>02050
          Length = 2483

 Score = 27.7 bits (60), Expect = 7.6,   Method: Compositional matrix adjust.
 Identities = 13/34 (38%), Positives = 18/34 (52%)
 Frame = -3

Query: 260  VYGLGRQVYDPKYCAAPTEPVIHNGSQGTGTNGS 293
            + GLG Q +  ++C A  +PV    S G G  GS
Sbjct: 1539 LCGLGLQSHSQRHCQAQCQPVR*ERSSGQGWQGS 1438
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|27777683|ref|NP_766356.1| GRAM domain containing 1B
[Mus musculus]
         (878 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

09079                                                                  89   6e-18
12261                                                                  41   0.002
>09079
          Length = 1987

 Score = 89.4 bits (220), Expect = 6e-18,   Method: Compositional matrix adjust.
 Identities = 44/105 (41%), Positives = 62/105 (59%)
 Frame = +3

Query: 577 TLTNPLAPKTATVRETQTMYKASQESECYVIDAEVLTHDVPYHDYFYTINRYTLTRVARN 636
           TL+ P  P T    E Q  YK S+  + Y +D E+    +PY D FY + RY LTRV+  
Sbjct: 372 TLSAPHLPST----EKQVCYKDSKPGKLYCVDCEICNGGIPYGDSFYVMLRYCLTRVSMT 539

Query: 637 KSRLRVSTELRYRKQPWGFVKTFIEKNFWSGLEDYFRHLETELTK 681
             R+RV++EL++RK   G  K+ IEK+  +GL DYFR+L   L +
Sbjct: 540 TCRVRVTSELKFRKSVMGMFKSMIEKSAVNGLTDYFRNLSAHLRR 674

 Score = 68.6 bits (166), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 38/93 (40%), Positives = 56/93 (60%), Gaps = 3/93 (3%)
 Frame = +3

Query: 782  NMMLFYKLWMLEYTTQTLTAWQGLRLQERL---PQSQTEWAQLLESQQKYHDTELQKWRE 838
            N +LFYKL  +E +T+ L +       + L   P+SQ +WA L+  Q+  H  E+ KW+E
Sbjct: 933  NAILFYKLRAIEASTRGLYSMYTDEEIDNLIQHPRSQEDWAHLIRQQRHLHQDEMSKWQE 1112

Query: 839  IIKSSVLLLDQMKDSLINLQNGIRSRDYTAESD 871
            I+ +SV LLDQMK SL+ LQ  ++ R  T  S+
Sbjct: 1113 ILHTSVQLLDQMKQSLVTLQTSLQVRTQTFASE 1211

 Score = 62.8 bits (151), Expect = 6e-10,   Method: Compositional matrix adjust.
 Identities = 34/91 (37%), Positives = 53/91 (58%), Gaps = 4/91 (4%)
 Frame = +2

Query: 518 RQYVNEVFNFSVDKLYDLLFTNSPFLRDFMEQRRFSDIIFHPWKKE--ENGNQSRVILYT 575
           + Y++EVFN +VDK+++ +FT+S F R F+  R   D+   PW  E  ++G++ R I YT
Sbjct: 179 KLYLDEVFNLNVDKVFENVFTDSAFFRVFVGSRSTFDLNLAPWDDELDDDGHRVRNISYT 358

Query: 576 ITLTNPLAPKTATVRETQTMYK--ASQESEC 604
           +TL N + P     RET  + +  A Q   C
Sbjct: 359 LTLNNSIGPAPPLHRETGVLQRQQAGQAVLC 451
>12261
          Length = 488

 Score = 41.2 bits (95), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 16/21 (76%), Positives = 18/21 (85%)
 Frame = -1

Query: 227 WYNVLSPTYKQRNEDFRKLFK 247
           WY +LSPTYK R+EDFRK FK
Sbjct: 65  WYTMLSPTYKSRSEDFRKTFK 3
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|170172546|ref|NP_852065.2| WD repeat domain 47 [Mus
musculus]
         (920 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

31118                                                                  82   7e-18
02960                                                                  61   2e-09
19949                                                                  61   2e-09
17266                                                                  59   1e-08
13335                                                                  55   2e-07
30256                                                                  54   2e-07
02147                                                                  53   7e-07
27465                                                                  53   7e-07
00561                                                                  52   1e-06
01805                                                                  49   1e-05
04358                                                                  48   2e-05
02090                                                                  47   5e-05
03387                                                                  46   8e-05
01327                                                                  46   9e-05
18981                                                                  45   1e-04
03156                                                                  45   1e-04
13278                                                                  45   2e-04
17598                                                                  44   2e-04
16199                                                                  44   2e-04
03395                                                                  42   0.001
07781                                                                  42   0.001
29912                                                                  42   0.001
14500                                                                  41   0.002
17602                                                                  41   0.002
12574                                                                  41   0.003
14555                                                                  41   0.003
19498                                                                  39   0.007
03044                                                                  39   0.010
21105                                                                  39   0.010
34005                                                                  37   0.043
12806                                                                  37   0.048
31474                                                                  36   0.072
15337                                                                  36   0.086
21921                                                                  36   0.091
27681                                                                  35   0.095
19140                                                                  35   0.12 
35607                                                                  35   0.13 
15780                                                                  35   0.13 
01598                                                                  34   0.30 
37180                                                                  33   0.48 
01462                                                                  33   0.68 
30727                                                                  33   0.71 
25880                                                                  32   0.93 
26939                                                                  32   0.99 
20662                                                                  31   1.7  
21164                                                                  31   2.2  
08355                                                                  31   2.4  
25400                                                                  31   2.8  
21763                                                                  31   2.8  
18320                                                                  31   2.9  
31384                                                                  30   3.3  
31054                                                                  30   3.6  
12960                                                                  30   3.8  
05420                                                                  30   5.1  
17298                                                                  29   7.4  
>31118
          Length = 390

 Score = 81.6 bits (200), Expect(2) = 7e-18,   Method: Composition-based stats.
 Identities = 34/66 (51%), Positives = 46/66 (69%)
 Frame = -2

Query: 840 HPHSSDVRSVRFSPGAHYLLTGSYDMKIKVTDLQGDLTKQLPLMVVGEHKDKVIQCRWHT 899
           +PHS+++R +RFSP A+Y+LT SYD  IK+TDLQGDL   +  +VV +HKDK I  RWH 
Sbjct: 389 YPHSAEIRCIRFSPSAYYMLTCSYDSTIKLTDLQGDLANDIASVVVAKHKDKAITIRWHP 210

Query: 900 QDLSFL 905
            +    
Sbjct: 209 TEFPLF 192

 Score = 28.1 bits (61), Expect(2) = 7e-18,   Method: Composition-based stats.
 Identities = 10/18 (55%), Positives = 15/18 (83%)
 Frame = -1

Query: 899 TQDLSFLSSSADRTVTLW 916
           +  +SF+S+SAD+T TLW
Sbjct: 213 SNGVSFISTSADKTATLW 160
>02960
          Length = 1577

 Score = 61.2 bits (147), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 69/263 (26%), Positives = 105/263 (39%), Gaps = 4/263 (1%)
 Frame = +2

Query: 661 HKGSIYCVAWSPCGQLLATGSNDKYVKVLPFNAETCNATGPDLEFSMHDGTIRDLAFMEG 720
           H  S+ CVA SP  Q + TGS DK +K+   +   CN  G   E +            E 
Sbjct: 752 HAASVDCVAVSPDSQQMCTGSWDKMLKLWSTD---CNVDGDQSEDT------------ER 886

Query: 721 PEXXXXXXXXXXXXDCNIYTTDCQRGQGLHALSGHTGHILALYTWSGWMIASGSQDKTVR 780
           P                + T           LSGH   + A+       + + S D ++R
Sbjct: 887 PSKKKKSAKSTTQTRVPVLT-----------LSGHAEAVSAVRWLDPHRVVTSSWDHSLR 1033

Query: 781 FWDLRVPSCVRVVGTTFHGTGSAVASVAVDPSGRLLATGQEDSSCMLYDIR---GGRMVQ 837
            WDL          T+      AV  VA  P   +L TG  D    L D R   G  +  
Sbjct: 1034LWDLHTAQ-----QTSLIQGSKAVLDVAYSPLSHMLITGSADRHVRLVDPRCSEGETVKC 1198

Query: 838 SYHPHSSDVRSVRFSPG-AHYLLTGSYDMKIKVTDLQGDLTKQLPLMVVGEHKDKVIQCR 896
           ++  H+  V  V +SP   H  L+GSYD  +K+ D +   + +  L  +  H+D+++   
Sbjct: 1199AFTSHTGWVTGVDWSPTREHLFLSGSYDNVLKLWDTR---SPKATLYDMNWHEDRILAVD 1369

Query: 897 WHTQDLSFLSSSADRTVTLWTYS 919
           W   +L  LS   D  + +++YS
Sbjct: 1370WSIPEL-LLSGGVDNKLHVFSYS 1435

 Score = 36.6 bits (83), Expect = 0.045,   Method: Compositional matrix adjust.
 Identities = 44/173 (25%), Positives = 74/173 (42%), Gaps = 28/173 (16%)
 Frame = +2

Query: 772 SGSQDKTVRFWDLRVPSCVRVVGTTFHGTGSAVASVAVDPSGRL--LATGQEDSSCMLYD 829
           SGS D TVR W  +  + + + G T       VA +  D S  +    TG  D + +++ 
Sbjct: 530 SGSYDNTVRLWSTKGEAIMTIPGHT--SPVKCVAWIKHDESSGVSTFVTGSHDQTALVWQ 703

Query: 830 I-RGGRMVQ---SYHPHSSDVRSVRFSPGAHYLLTGSYD--MKIKVTD--LQGDLTK--- 878
             R    V    S   H++ V  V  SP +  + TGS+D  +K+  TD  + GD ++   
Sbjct: 704 WQRETNEVDCRLSCRGHAASVDCVAVSPDSQQMCTGSWDKMLKLWSTDCNVDGDQSEDTE 883

Query: 879 ---------------QLPLMVVGEHKDKVIQCRWHTQDLSFLSSSADRTVTLW 916
                          ++P++ +  H + V   RW       ++SS D ++ LW
Sbjct: 884 RPSKKKKSAKSTTQTRVPVLTLSGHAEAVSAVRW-LDPHRVVTSSWDHSLRLW 1039
>19949
          Length = 903

 Score = 61.2 bits (147), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 39/114 (34%), Positives = 55/114 (48%), Gaps = 1/114 (0%)
 Frame = +2

Query: 804 VASVAVDPSGRLLATGQEDSSCMLYDIRGGRMVQSYHPHSSDVRSVRFSPGAHYLLTGSY 863
           V S+   P G   A+G  D +  L+DIR    + +Y  H+  V  +RFSP   ++ + S 
Sbjct: 2   VKSLDFHPYGAYTASGSMDCNVKLWDIRRKGCIYTYKGHTGCVCCLRFSPDGRWIASASE 181

Query: 864 DMKIKVTDLQ-GDLTKQLPLMVVGEHKDKVIQCRWHTQDLSFLSSSADRTVTLW 916
           D  +K+ DL  G L   L L     H+D V    +H  +    S SADRTV  W
Sbjct: 182 DGLVKLWDLTAGKLLTDLKL-----HRDAVNTIEFHPHEFLLASGSADRTVKFW 328

 Score = 38.5 bits (88), Expect = 0.011,   Method: Compositional matrix adjust.
 Identities = 40/153 (26%), Positives = 66/153 (43%), Gaps = 1/153 (0%)
 Frame = +2

Query: 672 PCGQLLATGSNDKYVKVLPFNAETCNATGPDLEFSMHDGTIRDLAFMEGPEXXXXXXXXX 731
           P G   A+GS D  VK+     + C  T     +  H G +  L F   P+         
Sbjct: 23  PYGAYTASGSMDCNVKLWDIRRKGCIYT-----YKGHTGCVCCLRF--SPDGRWIASASE 181

Query: 732 XXXDCNIYTTDCQRGQGLHALSGHTGHILAL-YTWSGWMIASGSQDKTVRFWDLRVPSCV 790
              D  +   D   G+ L  L  H   +  + +    +++ASGS D+TV+FWDL      
Sbjct: 182 ---DGLVKLWDLTAGKLLTDLKLHRDAVNTIEFHPHEFLLASGSADRTVKFWDLET---F 343

Query: 791 RVVGTTFHGTGSAVASVAVDPSGRLLATGQEDS 823
           +++ TT     +++ S+   P G  L +G +D+
Sbjct: 344 QLISTT-EPEANSIRSILFHPDGVCLYSGSKDT 439
>17266
          Length = 480

 Score = 58.5 bits (140), Expect = 1e-08,   Method: Composition-based stats.
 Identities = 41/140 (29%), Positives = 68/140 (48%), Gaps = 2/140 (1%)
 Frame = -1

Query: 772 SGSQDKTVRFWDLRVPSCVRVVGTTFHGTGSAVASVAVDPSGRLLATGQEDSSCMLYDIR 831
           SG+ D + + WD+R   C +    TF G  S + ++   P+G   ATG +D++C L+DIR
Sbjct: 408 SGACDASAKLWDVRDGMCKQ----TFSGHESDINAITYFPNGHAFATGSDDATCRLFDIR 241

Query: 832 GGRMVQSYHPHS--SDVRSVRFSPGAHYLLTGSYDMKIKVTDLQGDLTKQLPLMVVGEHK 889
             + +  Y   +    + SV FS     LL G  D    +     D+ KQ    V+  H 
Sbjct: 240 ADQEIGMYSHDNIICGITSVAFSKSGRLLLGGYDDFNCNIW----DVLKQERTGVLAGHD 73

Query: 890 DKVIQCRWHTQDLSFLSSSA 909
           ++V  C   T+D S +++ +
Sbjct: 72  NRV-SCLGVTEDGSAVATGS 16

 Score = 50.4 bits (119), Expect = 4e-06,   Method: Composition-based stats.
 Identities = 21/69 (30%), Positives = 38/69 (55%)
 Frame = -1

Query: 807 VAVDPSGRLLATGQEDSSCMLYDIRGGRMVQSYHPHSSDVRSVRFSPGAHYLLTGSYDMK 866
           +++ P  R   +G  D+S  L+D+R G   Q++  H SD+ ++ + P  H   TGS D  
Sbjct: 441 LSLAPDMRTFVSGACDASAKLWDVRDGMCKQTFSGHESDINAITYFPNGHAFATGSDDAT 262

Query: 867 IKVTDLQGD 875
            ++ D++ D
Sbjct: 261 CRLFDIRAD 235
>13335
          Length = 863

 Score = 54.7 bits (130), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 39/154 (25%), Positives = 68/154 (44%), Gaps = 12/154 (7%)
 Frame = +1

Query: 779 VRFWDLRVPSCVRVVGTTFHGTGSAVASVAVDPSGRLLATGQEDSSCMLYDIRGGRMVQS 838
           V  WD++  S   + G   H + S++      PS   L +G +D +  ++++   ++V+S
Sbjct: 4   VIVWDVKTGS---IKGEYQHASKSSIRVCKFSPSSSHLVSGSDDDTICMWEVATQKLVRS 174

Query: 839 YHPHSSDVRSVRFSPGAHYLLTGSYDMKIKVTDLQGDLTKQLPLMVVGEHKDKVIQCRW- 897
           Y  H   V ++ +SP  HYL++GS +  + V D      + L L  V  H   V  C + 
Sbjct: 175 YVGHEDSVMALAYSPNGHYLVSGSPNGDLYVWDASFGHCRHLTLR-VDAHDLGVTCCEFS 351

Query: 898 -----------HTQDLSFLSSSADRTVTLWTYSG 920
                       T +L   +   D  + LWT+S 
Sbjct: 352 PTFGTACAENSSTCNLLLATGGKDNLIKLWTFSA 453

 Score = 38.5 bits (88), Expect = 0.012,   Method: Compositional matrix adjust.
 Identities = 49/192 (25%), Positives = 78/192 (40%), Gaps = 29/192 (15%)
 Frame = +1

Query: 754 GHTGHILAL-YTWSGWMIASGSQDKTVRFWDLRVPSC----VRV----VGTT---FHGTG 801
           GH   ++AL Y+ +G  + SGS +  +  WD     C    +RV    +G T   F  T 
Sbjct: 181 GHEDSVMALAYSPNGHYLVSGSPNGDLYVWDASFGHCRHLTLRVDAHDLGVTCCEFSPTF 360

Query: 802 SAVASVAVDPSGRLLATGQEDSSCMLY----------------DIRGGRMVQSYHPHSSD 845
               +        LLATG +D+   L+                DI  G        HS  
Sbjct: 361 GTACAENSSTCNLLLATGGKDNLIKLWTFSAQVGSPEVTLQCRDILSG--------HSDL 516

Query: 846 VRSVRFSPGAHYLLTGSYDMKIKVTDLQGDLTKQLPLMVVGEHKDKVIQCRWHTQDLSFL 905
           V +  FSP +  L +GS+D  +++     D  K + L  +     + + C   + D + L
Sbjct: 517 VMACAFSPSSALLASGSFDKSVRL----WDSVKGVALFSIEACHSRFVTCCAFSIDGTLL 684

Query: 906 SS-SADRTVTLW 916
           +S S DR + +W
Sbjct: 685 ASGSMDRIIKIW 720

 Score = 37.0 bits (84), Expect = 0.034,   Method: Compositional matrix adjust.
 Identities = 64/233 (27%), Positives = 91/233 (39%), Gaps = 18/233 (7%)
 Frame = +1

Query: 608 QAVRAVAFHPSGSLYAVGSNSKTLRVCAYPEKMDASAHDNPKQPVVRFKRNKHHKGSIYC 667
            ++R   F PS S    GS+  T  +C +         +   Q +VR      H+ S+  
Sbjct: 64  SSIRVCKFSPSSSHLVSGSDDDT--ICMW---------EVATQKLVRSYVG--HEDSVMA 204

Query: 668 VAWSPCGQLLATGS--NDKYVKVLPFNA---ETCNATGPDL-----EFSMHDGTIRDLAF 717
           +A+SP G  L +GS   D YV    F      T      DL     EFS   GT    A 
Sbjct: 205 LAYSPNGHYLVSGSPNGDLYVWDASFGHCRHLTLRVDAHDLGVTCCEFSPTFGT----AC 372

Query: 718 MEGPEXXXXXXXXXXXXD-CNIYTTDCQRG------QGLHALSGHTGHILAL-YTWSGWM 769
            E               +   ++T   Q G      Q    LSGH+  ++A  ++ S  +
Sbjct: 373 AENSSTCNLLLATGGKDNLIKLWTFSAQVGSPEVTLQCRDILSGHSDLVMACAFSPSSAL 552

Query: 770 IASGSQDKTVRFWDLRVPSCVRVVGTTFHGTGSAVASVAVDPSGRLLATGQED 822
           +ASGS DK+VR WD  V           H       + ++D  G LLA+G  D
Sbjct: 553 LASGSFDKSVRLWD-SVKGVALFSIEACHSRFVTCCAFSID--GTLLASGSMD 702

 Score = 33.1 bits (74), Expect = 0.48,   Method: Compositional matrix adjust.
 Identities = 45/192 (23%), Positives = 73/192 (38%), Gaps = 16/192 (8%)
 Frame = +1

Query: 609 AVRAVAFHPSGSLYAVGSNSKTLRVCAYPEKMDASAHDNPKQPVVRFKRNKHHKGSIYCV 668
           +V A+A+ P+G     GS +  L V       DAS   + +   +R      H   + C 
Sbjct: 193 SVMALAYSPNGHYLVSGSPNGDLYV------WDAS-FGHCRHLTLRVDA---HDLGVTCC 342

Query: 669 AWSP------------CGQLLATGSNDKYVKVLPFNAETCNATGPDLEFSMHD--GTIRD 714
            +SP            C  LLATG  D  +K+  F+A+      P++     D      D
Sbjct: 343 EFSPTFGTACAENSSTCNLLLATGGKDNLIKLWTFSAQV---GSPEVTLQCRDILSGHSD 513

Query: 715 LAFMEGPEXXXXXXXXXXXXDCNIYTTDCQRGQGLHALSGHTGHILALYTWS--GWMIAS 772
           L  M                D ++   D  +G  L ++       +    +S  G ++AS
Sbjct: 514 LV-MACAFSPSSALLASGSFDKSVRLWDSVKGVALFSIEACHSRFVTCCAFSIDGTLLAS 690

Query: 773 GSQDKTVRFWDL 784
           GS D+ ++ W L
Sbjct: 691 GSMDRIIKIWKL 726
>30256
          Length = 961

 Score = 54.3 bits (129), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 48/172 (27%), Positives = 80/172 (46%), Gaps = 5/172 (2%)
 Frame = +3

Query: 750 HALSGHTGHILALYTWSGWMIASGSQDKTVRFWDLRVPSCVRVVGTTFHGTGSAVASVAV 809
           H L GH+  +  L + SG  + SGS+D T+R WD+    C+ V+       G   A   V
Sbjct: 144 HTLYGHSSTVRCL-SLSGKKVVSGSRDATLRVWDIESGHCLNVL------LGHMAAVRCV 302

Query: 810 DPSGRLLATGQEDSSCMLYDIRGGRMVQSYHPHSSDVRSVRFSPGAHYLLTGSYDMKIKV 869
              G+ + +G  D +  ++D      + +   H++ V S++F     Y+++GS D  I+V
Sbjct: 303 QYDGKRVVSGAXDYTVRVWDPDTASCLHTLQGHTNRVYSLQFD--GVYVVSGSLDTSIRV 476

Query: 870 TDLQ-GDLTKQL----PLMVVGEHKDKVIQCRWHTQDLSFLSSSADRTVTLW 916
            D++ G L   L     L    E KD ++           +S +AD TV +W
Sbjct: 477 WDVRCGKLVHTLMGHQSLTSGLELKDNLL-----------VSGNADSTVKVW 599
>02147
          Length = 1547

 Score = 52.8 bits (125), Expect = 7e-07,   Method: Compositional matrix adjust.
 Identities = 58/247 (23%), Positives = 92/247 (37%), Gaps = 38/247 (15%)
 Frame = +2

Query: 661 HKGSIYCVAWSPCGQLLATGSNDKYVKVLPFNAETCNATGPDLEFSMHDGTIRDLAFMEG 720
           HKG+++    +      ATG+ D   K+  ++AE     G +L+   H   ++ + F   
Sbjct: 170 HKGAVWGATLNREATRAATGAADFSAKI--WDAEK----GEELQTFSHKHIVKSVDFSHD 331

Query: 721 PEXXXXXXXXXXXXDCNIYTTDCQRGQGLHALSGHTGHIL-ALYTWSGWMIASGSQDKTV 779
                           ++  TD +      + +GHT +I  AL+   G  I S S DKTV
Sbjct: 332 GTALLTGSNEKLLKVFDLVNTDAEP----KSFAGHTSNIKGALFLSDGKRIISASDDKTV 499

Query: 780 RFWDLRVPSCVRVVGTTF-------------------HGTGSA----------------- 803
           R W L   +C  V   TF                   H    A                 
Sbjct: 500 RLWSLE--TCQEVQQLTFDTPPTSLTLSPDKNTIIVTHSQNIAFYQADTLREMKKFEAEA 673

Query: 804 -VASVAVDPSGRLLATGQEDSSCMLYDIRGGRMVQSYHPHSSDVRSVRFSPGAHYLLTGS 862
            ++S ++  S R    G ED     +D   G+ ++S+  H   V  VRFSP      +GS
Sbjct: 674 PISSASLHQSERFFVAGGEDFKMYKFDYETGKEIESFKGHFGPVHCVRFSPDGELYASGS 853

Query: 863 YDMKIKV 869
            D  +++
Sbjct: 854 EDGTLRL 874

 Score = 50.4 bits (119), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 39/122 (31%), Positives = 56/122 (45%)
 Frame = +2

Query: 796 TFHGTGSAVASVAVDPSGRLLATGQEDSSCMLYDIRGGRMVQSYHPHSSDVRSVRFSPGA 855
           TF G   AV    ++      ATG  D S  ++D   G  +Q++  H   V+SV FS   
Sbjct: 158 TFEGHKGAVWGATLNREATRAATGAADFSAKIWDAEKGEELQTF-SHKHIVKSVDFSHDG 334

Query: 856 HYLLTGSYDMKIKVTDLQGDLTKQLPLMVVGEHKDKVIQCRWHTQDLSFLSSSADRTVTL 915
             LLTGS +  +KV DL    T   P    G H   +    + +     +S+S D+TV L
Sbjct: 335 TALLTGSNEKLLKVFDLVN--TDAEPKSFAG-HTSNIKGALFLSDGKRIISASDDKTVRL 505

Query: 916 WT 917
           W+
Sbjct: 506 WS 511

 Score = 33.9 bits (76), Expect = 0.33,   Method: Compositional matrix adjust.
 Identities = 56/265 (21%), Positives = 97/265 (36%), Gaps = 34/265 (12%)
 Frame = +2

Query: 556 HEDSPCGSQNSSEHSVIKPSPGDSSGNL-SRSKGEEDDKSKKQFVCINTLEDTQAVRAVA 614
           H+ +  G+  + E +       D S  +    KGEE          + T      V++V 
Sbjct: 170 HKGAVWGATLNREATRAATGAADFSAKIWDAEKGEE----------LQTFSHKHIVKSVD 319

Query: 615 FHPSGSLYAVGSNSKTLRVCAYPEKMDASAHDNPKQPVVRFKRNKHHKGSIYCVAWSPCG 674
           F   G+    GSN K L+V       D    D   +P        + KG+++       G
Sbjct: 320 FSHDGTALLTGSNEKLLKV------FDLVNTD--AEPKSFAGHTSNIKGALFL----SDG 463

Query: 675 QLLATGSNDKYVKVLPFNAETCNAT--------------GPD-----------LEFSMHD 709
           + + + S+DK V++  ++ ETC                  PD           + F   D
Sbjct: 464 KRIISASDDKTVRL--WSLETCQEVQQLTFDTPPTSLTLSPDKNTIIVTHSQNIAFYQAD 637

Query: 710 GTIRDLAFMEGPEXXXXXXXXXXX-------XDCNIYTTDCQRGQGLHALSGHTGHILAL 762
            T+R++   E                      D  +Y  D + G+ + +  GH G +  +
Sbjct: 638 -TLREMKKFEAEAPISSASLHQSERFFVAGGEDFKMYKFDYETGKEIESFKGHFGPVHCV 814

Query: 763 -YTWSGWMIASGSQDKTVRFWDLRV 786
            ++  G + ASGS+D T+R W   +
Sbjct: 815 RFSPDGELYASGSEDGTLRLWQTTI 889

 Score = 29.6 bits (65), Expect = 5.8,   Method: Compositional matrix adjust.
 Identities = 17/46 (36%), Positives = 20/46 (43%), Gaps = 13/46 (28%)
 Frame = +2

Query: 610 VRAVAFHPSGSLYAVGSNSKTLRV-------------CAYPEKMDA 642
           V  V F P G LYA GS   TLR+             C  P++ DA
Sbjct: 803 VHCVRFSPDGELYASGSEDGTLRLWQTTIGRTYGLWKCVIPDEADA 940
>27465
          Length = 658

 Score = 52.8 bits (125), Expect = 7e-07,   Method: Compositional matrix adjust.
 Identities = 33/122 (27%), Positives = 58/122 (47%), Gaps = 5/122 (4%)
 Frame = -1

Query: 757 GHILAL----YTWSGWMIASGSQDKTVRFWDLRVPSCVRVVGTTFHGTGSAVASVAVD-P 811
            HIL L    +  SG    +GS D+T + WD      +     T  G  + V ++A + P
Sbjct: 367 AHILPLTNVAFNKSGSSFITGSYDRTCKIWDTASAEELH----TLEGHRNVVYAIAFNNP 200

Query: 812 SGRLLATGQEDSSCMLYDIRGGRMVQSYHPHSSDVRSVRFSPGAHYLLTGSYDMKIKVTD 871
            G  + TG  D +C L+    G+   +   H++++  V F+P +  + TGS D   ++ D
Sbjct: 199 FGDKVITGSFDKTCKLWSTADGKCYHTLRGHTAEIVCVSFNPSSTLIATGSMDTTCRLWD 20

Query: 872 LQ 873
           ++
Sbjct: 19  VE 14

 Score = 34.7 bits (78), Expect = 0.20,   Method: Compositional matrix adjust.
 Identities = 42/174 (24%), Positives = 64/174 (36%), Gaps = 2/174 (1%)
 Frame = -1

Query: 613 VAFHPSGSLYAVGSNSKTLRVCAYPEKMDASAHDNPKQPVVRFKRNKHHKGSIYCVAW-S 671
           VAF+ SGS +  GS  +T ++        ASA +            + H+  +Y +A+ +
Sbjct: 343 VAFNKSGSSFITGSYDRTCKIWD-----TASAEE--------LHTLEGHRNVVYAIAFNN 203

Query: 672 PCGQLLATGSNDKYVKVLPFNAETCNATGPDLEFSMHDGTIRDLAFMEGPEXXXXXXXXX 731
           P G  + TGS DK  K+                +S  DG                     
Sbjct: 202 PFGDKVITGSFDKTCKL----------------WSTADG--------------------- 134

Query: 732 XXXDCNIYTTDCQRGQGLHALSGHTGHILAL-YTWSGWMIASGSQDKTVRFWDL 784
                          +  H L GHT  I+ + +  S  +IA+GS D T R WD+
Sbjct: 133 ---------------KCYHTLRGHTAEIVCVSFNPSSTLIATGSMDTTCRLWDV 17

 Score = 29.6 bits (65), Expect = 5.7,   Method: Compositional matrix adjust.
 Identities = 26/85 (30%), Positives = 37/85 (43%), Gaps = 2/85 (2%)
 Frame = -1

Query: 601 INTLEDTQ-AVRAVAFH-PSGSLYAVGSNSKTLRVCAYPEKMDASAHDNPKQPVVRFKRN 658
           ++TLE  +  V A+AF+ P G     GS  KT   C      D   +   +         
Sbjct: 256 LHTLEGHRNVVYAIAFNNPFGDKVITGSFDKT---CKLWSTADGKCYHTLRG-------- 110

Query: 659 KHHKGSIYCVAWSPCGQLLATGSND 683
             H   I CV+++P   L+ATGS D
Sbjct: 109 --HTAEIVCVSFNPSSTLIATGSMD 41
>00561
          Length = 1003

 Score = 51.6 bits (122), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 31/104 (29%), Positives = 55/104 (52%)
 Frame = -3

Query: 769 MIASGSQDKTVRFWDLRVPSCVRVVGTTFHGTGSAVASVAVDPSGRLLATGQEDSSCMLY 828
           +I S   D+TV+ W+L   +C   +    HG    + +V V P G L  +G +DS  +L+
Sbjct: 563 IIVSCGWDRTVKVWNLA--NCK--LKNNHHGHNGYLNTVTVSPDGSLCTSGGKDSKALLW 396

Query: 829 DIRGGRMVQSYHPHSSDVRSVRFSPGAHYLLTGSYDMKIKVTDL 872
           D+  G+ + +   H+  + ++ FSP  ++L   +Y   IK+ DL
Sbjct: 395 DLNDGKNLYTLE-HNDIINALCFSPNRYWLCV-AYGPSIKIWDL 270

 Score = 43.1 bits (100), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 31/104 (29%), Positives = 47/104 (45%), Gaps = 3/104 (2%)
 Frame = -3

Query: 772 SGSQDKTVRFWDLRVPSCVRVVGTTFHGTGSAVASVAVDPSGRLLATGQEDSSCMLYD-I 830
           SGS D+T+R WDL      R     F G    V SVA     R + +G  D +  L++ +
Sbjct: 815 SGSWDQTLRLWDLAAGKTTR----RFEGHTKDVLSVAFSADNRQIVSGSRDKTIKLWNTL 648

Query: 831 RGGRMVQSYHPHSSDVRSVRFSPGAH--YLLTGSYDMKIKVTDL 872
              +       H+  V  VRFSP      +++  +D  +KV +L
Sbjct: 647 AECKFTIQEDGHTDWVSCVRFSPNHSNPIIVSCGWDRTVKVWNL 516

 Score = 34.7 bits (78), Expect = 0.20,   Method: Compositional matrix adjust.
 Identities = 25/89 (28%), Positives = 42/89 (47%), Gaps = 1/89 (1%)
 Frame = -3

Query: 829 DIRGGRMVQSYHPHSSDVRSVRFSPGAHYLLTGSYDMKIKVTDLQ-GDLTKQLPLMVVGE 887
           D   G   +  + HS  +  V  S   +Y L+GS+D  +++ DL  G  T++      G 
Sbjct: 908 DTNYGYPQKRLYGHSHFISDVVLSSDGNYALSGSWDQTLRLWDLAAGKTTRRFE----GH 741

Query: 888 HKDKVIQCRWHTQDLSFLSSSADRTVTLW 916
            KD V+   +   +   +S S D+T+ LW
Sbjct: 740 TKD-VLSVAFSADNRQIVSGSRDKTIKLW 657
>01805
          Length = 2124

 Score = 48.9 bits (115), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 37/139 (26%), Positives = 61/139 (43%), Gaps = 18/139 (12%)
 Frame = -1

Query: 767 GWMIASGSQDKTVRFWDLRVPSCVRVVGT----------------TFHGTGSAVASVAVD 810
           G  +A GS +  +  WDL +   V    T                +  G   AV  ++ +
Sbjct: 726 GNFVAIGSMEPVIEIWDLDIMESVGPTLTLGSKPKKTKKKMKQKESVTGHTQAVLDLSWN 547

Query: 811 PSGR-LLATGQEDSSCMLYDIRGGRMVQSYHPHSSDVRSVRFSPGA-HYLLTGSYDMKIK 868
            + R +LA+   D++  L+D+  G+M  ++  HS +V+   + P     LLTGS+D  +K
Sbjct: 546 RNARHVLASASADTTVALWDLSEGKMAMNFTQHSREVQCCNWHPQEEQTLLTGSFDNTVK 367

Query: 869 VTDLQGDLTKQLPLMVVGE 887
           V D +   T      V GE
Sbjct: 366 VVDCRSAETCHKSWTVEGE 310
>04358
          Length = 2430

 Score = 47.8 bits (112), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 45/133 (33%), Positives = 62/133 (46%), Gaps = 12/133 (9%)
 Frame = +1

Query: 752  LSGH---TGHILALYTWSGWMIASGSQDKTVRFWDLRVPSCVRVVGTTFHG---TGSAVA 805
            L+GH      I  L+T  G +I + S D TVR WD R      V    F G   T  +V 
Sbjct: 1408 LTGHDDVISSIRFLHTDPG-LIMTASHDHTVRIWDPRASVSKEV--QRFSGEQNTKCSVL 1578

Query: 806  SVAVDPSGRLLATGQE----DSSCMLYDIRGGRMVQSYH-PHSSDVRSVRFSPGAH-YLL 859
            S  V+ S R+L  G E    D+  + +D R  +++  Y   H  D+  V F P +   LL
Sbjct: 1579 SCDVNISDRVLCAGTEMSNDDAYLLFWDRRKDKLLGCYEDSHHDDITQVHFGPTSEKTLL 1758

Query: 860  TGSYDMKIKVTDL 872
            TGS D  + V D+
Sbjct: 1759 TGSTDGLVNVFDV 1797
>02090
          Length = 1841

 Score = 46.6 bits (109), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 36/141 (25%), Positives = 59/141 (41%)
 Frame = -3

Query: 776  DKTVRFWDLRVPSCVRVVGTTFHGTGSAVASVAVDPSGRLLATGQEDSSCMLYDIRGGRM 835
            D  +  WDL   + VR     F G     + + + P G  L TG  D++   +D+R GR 
Sbjct: 1563 DGNIAVWDLHNQTLVR----QFQGHTDGASCIDISPDGTKLWTGGLDNTVRSWDLREGRQ 1396

Query: 836  VQSYHPHSSDVRSVRFSPGAHYLLTGSYDMKIKVTDLQGDLTKQLPLMVVGEHKDKVIQC 895
            +Q  H  SS + S+ + P   +L  G     ++V         QL L     H+  V+  
Sbjct: 1395 LQQ-HDFSSQIFSLGYCPTGEWLAVGMESSNVEVLHHSKPDKYQLHL-----HESCVLSL 1234

Query: 896  RWHTQDLSFLSSSADRTVTLW 916
            ++      F+S+  D  +  W
Sbjct: 1233 KFAYCGKWFVSTGKDNLLNAW 1171
>03387
          Length = 1891

 Score = 45.8 bits (107), Expect = 8e-05,   Method: Compositional matrix adjust.
 Identities = 40/162 (24%), Positives = 73/162 (45%), Gaps = 14/162 (8%)
 Frame = +1

Query: 769 MIASGSQDKTVRFWDLRVPSCVRVVGTTFHGTGSAVASVAVDP-SGRLLATGQEDSSCML 827
           +  S + D+ +  WD R  +  +        T + V  ++ +P S  +LATG  D +  L
Sbjct: 556 LFGSVADDQKLMIWDTRSNTTSKPSHVVDAHT-AEVNCLSFNPYSEFILATGSADKTVAL 732

Query: 828 YDIRGGRM-VQSYHPHSSDVRSVRFSPGAHYLLTGS-YDMKIKVTDLQGDLTKQLP---- 881
           +D+R  ++ + S+  H  ++  V++SP    +L  S  D ++ V DL     +QLP    
Sbjct: 733 WDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLHVWDLSKIGEEQLPEDAE 912

Query: 882 ------LMVVGEHKDKVIQCRWHTQDLSFL-SSSADRTVTLW 916
                 L + G H  K+    W+  +   + S S D  + +W
Sbjct: 913 DGPPELLFIHGGHTAKISDFSWNPNEPWIVCSVSEDNIMQVW 1038

 Score = 38.1 bits (87), Expect = 0.016,   Method: Compositional matrix adjust.
 Identities = 42/184 (22%), Positives = 77/184 (41%), Gaps = 10/184 (5%)
 Frame = +1

Query: 657 RNKHHKGSIYCVAWSPC--GQLLATGSNDKYVKVLPFNAETCNATGPDLE--FSMHDGTI 712
           R K H+   Y ++W+P   G LL + S+D  + +   N+    +   D    F+ H   +
Sbjct: 346 RLKGHQKEGYGLSWNPNLNGHLL-SASDDHTICLWDINSTQRESRVVDAHTIFTGHTSVV 522

Query: 713 RDLAFMEGPEXXXXXXXXXXXXDCNIYTTDCQRG---QGLHALSGHTGHI--LALYTWSG 767
            D+A+                 D  +   D +     +  H +  HT  +  L+   +S 
Sbjct: 523 EDVAW----HLLHESLFGSVADDQKLMIWDTRSNTTSKPSHVVDAHTAEVNCLSFNPYSE 690

Query: 768 WMIASGSQDKTVRFWDLRVPSCVRVVGTTFHGTGSAVASVAVDPSGR-LLATGQEDSSCM 826
           +++A+GS DKTV  WDLR    +++   +F      +  V   P    +LA+   D    
Sbjct: 691 FILATGSADKTVALWDLR---NLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLH 861

Query: 827 LYDI 830
           ++D+
Sbjct: 862 VWDL 873
>01327
          Length = 2215

 Score = 45.8 bits (107), Expect = 9e-05,   Method: Compositional matrix adjust.
 Identities = 32/138 (23%), Positives = 65/138 (47%), Gaps = 1/138 (0%)
 Frame = +3

Query: 735 DCNIYTTDCQRGQGLHALSGHTGHILAL-YTWSGWMIASGSQDKTVRFWDLRVPSCVRVV 793
           D ++   D Q G+     +GH   I  + Y  S   + S S+DKT++ W       +R  
Sbjct: 102 DKSVVLYDYQNGRLEDRWTGHDREITKVCYGASCNGMFSASRDKTIKMWQRGNSHSIR-- 275

Query: 794 GTTFHGTGSAVASVAVDPSGRLLATGQEDSSCMLYDIRGGRMVQSYHPHSSDVRSVRFSP 853
              F G    V ++ ++    LL +G  D++  ++D+  G  ++  +   + V  V++ P
Sbjct: 276 --DFIGHDMVVTAIHLNTDNTLLCSGSRDNTVRIWDVETGACLRQNNIPQNLVTDVKWLP 449

Query: 854 GAHYLLTGSYDMKIKVTD 871
           G+H ++    D ++++ D
Sbjct: 450 GSHLIIQAGEDKEVRIYD 503

 Score = 38.5 bits (88), Expect = 0.011,   Method: Compositional matrix adjust.
 Identities = 26/94 (27%), Positives = 40/94 (42%)
 Frame = +3

Query: 769 MIASGSQDKTVRFWDLRVPSCVRVVGTTFHGTGSAVASVAVDPSGRLLATGQEDSSCMLY 828
           ++ SGS+D TVR WD+   +C+R          + V  V   P   L+    ED    +Y
Sbjct: 333 LLCSGSRDNTVRIWDVETGACLRQNNI----PQNLVTDVKWLPGSHLIIQAGEDKEVRIY 500

Query: 829 DIRGGRMVQSYHPHSSDVRSVRFSPGAHYLLTGS 862
           D R   +V+S+        S   +    + LT S
Sbjct: 501 DSRTLGIVRSFTKKQYIQMSCDVTADGQFCLTCS 602

 Score = 35.0 bits (79), Expect = 0.15,   Method: Compositional matrix adjust.
 Identities = 25/102 (24%), Positives = 44/102 (43%)
 Frame = +3

Query: 815 LLATGQEDSSCMLYDIRGGRMVQSYHPHSSDVRSVRFSPGAHYLLTGSYDMKIKVTDLQG 874
           L  +G +D S +LYD + GR+   +  H  ++  V +    + + + S D  IK+   Q 
Sbjct: 81  LCLSGSKDKSVVLYDYQNGRLEDRWTGHDREITKVCYGASCNGMFSASRDKTIKM--WQR 254

Query: 875 DLTKQLPLMVVGEHKDKVIQCRWHTQDLSFLSSSADRTVTLW 916
             +  +   +   H   V     +T +    S S D TV +W
Sbjct: 255 GNSHSIRDFI--GHDMVVTAIHLNTDNTLLCSGSRDNTVRIW 374

 Score = 30.4 bits (67), Expect = 3.0,   Method: Compositional matrix adjust.
 Identities = 16/50 (32%), Positives = 25/50 (50%)
 Frame = +3

Query: 769 MIASGSQDKTVRFWDLRVPSCVRVVGTTFHGTGSAVASVAVDPSGRLLAT 818
           +IA+ S+D +VR W++    C  V    F GTG   + +A      L+ T
Sbjct: 735 LIATASRDCSVRVWNMFTKEC--VCEQNFEGTGPLTSMIAYGDGSVLVGT 878
>18981
          Length = 407

 Score = 45.4 bits (106), Expect = 1e-04,   Method: Composition-based stats.
 Identities = 36/134 (26%), Positives = 65/134 (48%)
 Frame = -2

Query: 769 MIASGSQDKTVRFWDLRVPSCVRVVGTTFHGTGSAVASVAVDPSGRLLATGQEDSSCMLY 828
           MI S + D+T+R W L+  +C+     T  G    V  V +   GR + +G  D + +++
Sbjct: 382 MIISAATDRTLRVWCLK-NTCLL---HTLRGHNDDVECVCI--YGRRVVSGSWDKTLIVW 221

Query: 829 DIRGGRMVQSYHPHSSDVRSVRFSPGAHYLLTGSYDMKIKVTDLQGDLTKQLPLMVVGEH 888
           ++  GR V   H H+  + +V+F  G    ++GS D  ++   L  D  + L  M  G+ 
Sbjct: 220 EVDTGRPVHQLHGHTEAITAVQFDEGK--AVSGSADGDVRTWAL--DTGQCLLTMTTGQ- 56

Query: 889 KDKVIQCRWHTQDL 902
            D  + C  + Q++
Sbjct: 55  -DIEVYCVVYNQEV 17

 Score = 30.0 bits (66), Expect = 4.8,   Method: Composition-based stats.
 Identities = 19/62 (30%), Positives = 28/62 (45%)
 Frame = -2

Query: 749 LHALSGHTGHILALYTWSGWMIASGSQDKTVRFWDLRVPSCVRVVGTTFHGTGSAVASVA 808
           LH L GH   +  +  + G  + SGS DKT+  W++     V       HG   A+ +V 
Sbjct: 319 LHTLRGHNDDVECVCIY-GRRVVSGSWDKTLIVWEVDTGRPVH----QLHGHTEAITAVQ 155

Query: 809 VD 810
            D
Sbjct: 154 FD 149
>03156
          Length = 1014

 Score = 45.1 bits (105), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 23/100 (23%), Positives = 50/100 (50%)
 Frame = +1

Query: 772 SGSQDKTVRFWDLRVPSCVRVVGTTFHGTGSAVASVAVDPSGRLLATGQEDSSCMLYDIR 831
           S S+DKT++ W       +R     F G    V ++ ++    LL +G  D++  ++D+ 
Sbjct: 106 SASRDKTIKMWQRGNSHSIR----DFIGHDMVVTAIHLNTDNTLLCSGSRDNTVRIWDVE 273

Query: 832 GGRMVQSYHPHSSDVRSVRFSPGAHYLLTGSYDMKIKVTD 871
            G  ++  +   + V  V++ PG+H ++    D ++++ D
Sbjct: 274 TGACLRQNNIPQNLVTDVKWLPGSHLIIQAGEDKEVRIYD 393

 Score = 38.5 bits (88), Expect = 0.013,   Method: Compositional matrix adjust.
 Identities = 26/94 (27%), Positives = 40/94 (42%)
 Frame = +1

Query: 769 MIASGSQDKTVRFWDLRVPSCVRVVGTTFHGTGSAVASVAVDPSGRLLATGQEDSSCMLY 828
           ++ SGS+D TVR WD+   +C+R          + V  V   P   L+    ED    +Y
Sbjct: 223 LLCSGSRDNTVRIWDVETGACLRQNNI----PQNLVTDVKWLPGSHLIIQAGEDKEVRIY 390

Query: 829 DIRGGRMVQSYHPHSSDVRSVRFSPGAHYLLTGS 862
           D R   +V+S+        S   +    + LT S
Sbjct: 391 DSRTLGIVRSFTKKQYIQMSCDVTADGQFCLTCS 492

 Score = 30.4 bits (67), Expect = 3.3,   Method: Compositional matrix adjust.
 Identities = 16/50 (32%), Positives = 25/50 (50%)
 Frame = +1

Query: 769 MIASGSQDKTVRFWDLRVPSCVRVVGTTFHGTGSAVASVAVDPSGRLLAT 818
           +IA+ S+D +VR W++    C  V    F GTG   + +A      L+ T
Sbjct: 625 LIATASRDCSVRVWNMFTKEC--VCEQNFEGTGPLTSMIAYGDGSVLVGT 768
>13278
          Length = 870

 Score = 44.7 bits (104), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 24/71 (33%), Positives = 37/71 (52%)
 Frame = +1

Query: 769 MIASGSQDKTVRFWDLRVPSCVRVVGTTFHGTGSAVASVAVDPSGRLLATGQEDSSCMLY 828
           ++AS S D TVR W++    C+     T       V SVA  P G+ LA+G  D    ++
Sbjct: 118 ILASASFDSTVRLWEVERGLCLH----TLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIW 285

Query: 829 DIRGGRMVQSY 839
           +++ G +V SY
Sbjct: 286 NVQTGSLVHSY 318

 Score = 41.2 bits (95), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 19/59 (32%), Positives = 33/59 (55%)
 Frame = +1

Query: 815 LLATGQEDSSCMLYDIRGGRMVQSYHPHSSDVRSVRFSPGAHYLLTGSYDMKIKVTDLQ 873
           +LA+   DS+  L+++  G  + +   H   V SV FSP   YL +GS+D  + + ++Q
Sbjct: 118 ILASASFDSTVRLWEVERGLCLHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNVQ 294

 Score = 37.7 bits (86), Expect = 0.021,   Method: Compositional matrix adjust.
 Identities = 34/125 (27%), Positives = 57/125 (45%), Gaps = 2/125 (1%)
 Frame = +1

Query: 735 DCNIYTTDCQRGQGLHALSGHTGHILAL-YTWSGWMIASGSQDKTVRFWDLRVPSCVRVV 793
           D  +   + +RG  LH L+ H   + ++ ++  G  +ASGS DK V  W+++  S V   
Sbjct: 139 DSTVRLWEVERGLCLHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNVQTGSLVH-- 312

Query: 794 GTTFHGTGSAVASVAVDPSGRLLATGQEDSSCMLYDIRG-GRMVQSYHPHSSDVRSVRFS 852
             ++ GTG  +  V  +  G  +     D S  + D+R   +   S+H       S +F 
Sbjct: 313 --SYKGTG-GIFEVCWNHRGDKVGASASDGSVFVLDLRK*DKCSNSWHMLLLPPLSPKFL 483

Query: 853 PGAHY 857
           P A Y
Sbjct: 484 PCAGY 498
>17598
          Length = 875

 Score = 44.3 bits (103), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 27/104 (25%), Positives = 54/104 (51%)
 Frame = +1

Query: 769 MIASGSQDKTVRFWDLRVPSCVRVVGTTFHGTGSAVASVAVDPSGRLLATGQEDSSCMLY 828
           ++ S S DKT++ WD +  +    +  TF G  + + ++ +      LA+G +D   M +
Sbjct: 424 LVVSASMDKTIKVWDNQTMT----LKHTFVGHKTQINAIDLALKTYYLASGSKDGIVMTW 591

Query: 829 DIRGGRMVQSYHPHSSDVRSVRFSPGAHYLLTGSYDMKIKVTDL 872
           +I+ G  +        +V +V+FSP  ++L  G+ +  I++ DL
Sbjct: 592 NIQNGTFLGKIDC-DCEVNAVKFSPNKYWLFVGTSE-GIQIWDL 717

 Score = 40.0 bits (92), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 29/140 (20%), Positives = 58/140 (41%), Gaps = 1/140 (0%)
 Frame = +1

Query: 735 DCNIYTTDCQRGQGLHALSGHTGHILAL-YTWSGWMIASGSQDKTVRFWDLRVPSCVRVV 793
           D  +   D ++G        HT   LA+ ++     IASG +DK ++ W+  V  C   V
Sbjct: 184 DATLRLWDIKKGNTTRRFISHTRDALAVAFSPDNRQIASGGRDKALKIWNT-VGECKFTV 360

Query: 794 GTTFHGTGSAVASVAVDPSGRLLATGQEDSSCMLYDIRGGRMVQSYHPHSSDVRSVRFSP 853
               H           D    L+ +   D +  ++D +   +  ++  H + + ++  + 
Sbjct: 361 DANSHQDWVTCVKFHQDAKSPLVVSASMDKTIKVWDNQTMTLKHTFVGHKTQINAIDLAL 540

Query: 854 GAHYLLTGSYDMKIKVTDLQ 873
             +YL +GS D  +   ++Q
Sbjct: 541 KTYYLASGSKDGIVMTWNIQ 600
>16199
          Length = 694

 Score = 44.3 bits (103), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 36/131 (27%), Positives = 60/131 (45%), Gaps = 1/131 (0%)
 Frame = +1

Query: 743 CQRGQGLHALSGHTG-HILALYTWSGWMIASGSQDKTVRFWDLRVPSCVRVVGTTFHGTG 801
           C+RGQ    L G  G   L L   +G+ +A+ ++D  V+ WDLR    ++   T   G  
Sbjct: 169 CERGQ----LPGPPGTRHLHLLL*NGYYLATSAEDSVVKLWDLRK---LKNFKTLQLGDK 327

Query: 802 SAVASVAVDPSGRLLATGQEDSSCMLYDIRGGRMVQSYHPHSSDVRSVRFSPGAHYLLTG 861
             V ++  D SG  LA    D    +Y  +    +  ++ H++    VRF   A+++ + 
Sbjct: 328 YEVKALCFDQSGTYLAVAGSD--VRVYLCKQWNELAVFNDHTATATGVRFGTNANFIASA 501

Query: 862 SYDMKIKVTDL 872
           S D  +K   L
Sbjct: 502 SMDRSLKFFGL 534

 Score = 33.9 bits (76), Expect = 0.33,   Method: Composition-based stats.
 Identities = 16/50 (32%), Positives = 25/50 (50%)
 Frame = +2

Query: 803 AVASVAVDPSGRLLATGQEDSSCMLYDIRGGRMVQSYHPHSSDVRSVRFS 852
           A+      P G + ATG EDS   ++D++    V ++  H   V S+ FS
Sbjct: 77  ALTCAQFHPDGLIFATGTEDSVIKIWDLKERANVANFQGHQGPVTSISFS 226

 Score = 29.6 bits (65), Expect = 5.9,   Method: Compositional matrix adjust.
 Identities = 17/78 (21%), Positives = 30/78 (38%), Gaps = 2/78 (2%)
 Frame = +2

Query: 599 VCINTLEDTQAVRAVAFHPSGSLYAVGSNSKTLRVCAYPEKMDASAHDNPKQPV--VRFK 656
           VC  +     A+    FHP G ++A G+    +++    E+ + +     + PV  + F 
Sbjct: 47  VCDKSGPSVPALTCAQFHPDGLIFATGTEDSVIKIWDLKERANVANFQGHQGPVTSISFS 226

Query: 657 RNKHHKGSIYCVAWSPCG 674
                        WS CG
Sbjct: 227 ETDTTWPRQQKTLWSNCG 280
>03395
          Length = 2795

 Score = 42.0 bits (97), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 23/100 (23%), Positives = 47/100 (47%)
 Frame = +2

Query: 770 IASGSQDKTVRFWDLRVPSCVRVVGTTFHGTGSAVASVAVDPSGRLLATGQEDSSCMLYD 829
           I +   D  + +W++     +R +  +  G   A+ ++ +D  G+ + TG EDS   L+ 
Sbjct: 314 ILTSGTDHKIGYWEVGDGGLLRELEGSQTG---AINTIDIDRDGQTILTGGEDSLLKLWR 484

Query: 830 IRGGRMVQSYHPHSSDVRSVRFSPGAHYLLTGSYDMKIKV 869
              G +  +   HS+ +   R  P  HY+++G  D  + +
Sbjct: 485 YNEGEVTHTGIGHSNQITKARICPNRHYIVSGGEDGALHI 604

 Score = 31.2 bits (69), Expect = 2.2,   Method: Compositional matrix adjust.
 Identities = 20/80 (25%), Positives = 37/80 (46%), Gaps = 9/80 (11%)
 Frame = +2

Query: 846 VRSVRFSPGAHYLLTGSYDMKIKVTDL---------QGDLTKQLPLMVVGEHKDKVIQCR 896
           V ++  +     L++G  + +++V D+         +GDL   +      EHK KV   +
Sbjct: 5   VTAIAVTSCGTKLVSGGGEGQVRVWDIVKDMLTGKTRGDLVANMK-----EHKGKVTAIQ 169

Query: 897 WHTQDLSFLSSSADRTVTLW 916
            HT D   +S+S D +  +W
Sbjct: 170 IHTNDRCCVSASTDGSTIIW 229
>07781
          Length = 1269

 Score = 42.0 bits (97), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 35/115 (30%), Positives = 50/115 (43%), Gaps = 2/115 (1%)
 Frame = -2

Query: 759 ILALYTWSGWMIASGSQDKTVRFWDLRVPSCVRVVGTTFHGTGSAVASVAVDPSGR-LLA 817
           I A   W+  +I SGS D  ++ WDLRV +   +  + F      V S+   P    LLA
Sbjct: 779 ICAFDQWNTELIYSGSDDCKLKVWDLRVGTTPVLTNSRF---TMGVTSIQSCPQREHLLA 609

Query: 818 TGQEDSSCMLYDIRGGRMVQSYHPHSSDVRSVRFSP-GAHYLLTGSYDMKIKVTD 871
            G  D +  L+D R  R   S       V  V++ P  A Y+LT +      + D
Sbjct: 608 VGSYDENLRLFDTRHMRQPLSTTALEGGVWRVKWDPFXARYVLTATMHNGFHIVD 444
>29912
          Length = 510

 Score = 41.6 bits (96), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 20/57 (35%), Positives = 30/57 (52%)
 Frame = +3

Query: 661 HKGSIYCVAWSPCGQLLATGSNDKYVKVLPFNAETCNATGPDLEFSMHDGTIRDLAF 717
           H   +  + WSP G+ LA+G+ND  + V P      N+T P   FS H   ++ LA+
Sbjct: 255 HSQEVCGLRWSPDGKYLASGANDNLLCVWPAQVTGGNSTQPLHTFSQHQAAVKALAW 425

 Score = 37.4 bits (85), Expect = 0.025,   Method: Compositional matrix adjust.
 Identities = 30/121 (24%), Positives = 58/121 (47%), Gaps = 5/121 (4%)
 Frame = +3

Query: 738 IYTTDCQRGQGLHALSGHTGHILALYTWSGWMIASGSQDKTVRFWDLRVPSCVRVVGTTF 797
           +   D  + + L  ++GH   + +L +W+ ++++SGS+   +   D+RV      VG T 
Sbjct: 81  VQVWDVTQQKKLRTMAGHAARVGSL-SWNSFIVSSGSRSGNIHHHDVRVAD--HHVG-TL 248

Query: 798 HGTGSAVASVAVDPSGRLLATGQEDSSCMLY--DIRGGRMVQSYHP---HSSDVRSVRFS 852
            G    V  +   P G+ LA+G  D+   ++   + GG   Q  H    H + V+++ + 
Sbjct: 249 SGHSQEVCGLRWSPDGKYLASGANDNLLCVWPAQVTGGNSTQPLHTFSQHQAAVKALAWC 428

Query: 853 P 853
           P
Sbjct: 429 P 431
>14500
          Length = 1238

 Score = 41.2 bits (95), Expect = 0.002,   Method: Composition-based stats.
 Identities = 20/56 (35%), Positives = 29/56 (51%)
 Frame = +2

Query: 661 HKGSIYCVAWSPCGQLLATGSNDKYVKVLPFNAETCNATGPDLEFSMHDGTIRDLA 716
           H   +  + WSP G+ LA+G+ND  + V P      N+T P   FS H   ++ LA
Sbjct: 56  HSQEVCGLRWSPDGKYLASGANDNLLCVWPAQVTGGNSTQPLHTFSQHQAAVKALA 223
>17602
          Length = 481

 Score = 41.2 bits (95), Expect = 0.002,   Method: Composition-based stats.
 Identities = 23/93 (24%), Positives = 42/93 (45%), Gaps = 1/93 (1%)
 Frame = +3

Query: 780 RFWDLRVPSCVRVVGTTFHGTGSAVASVAVDPSGRLLATGQEDSSCMLYDIRGGRMVQSY 839
           R WD++   C++    T       V +V  +  G L+ +   D  C ++D   G+ + + 
Sbjct: 3   RIWDVKTGKCLK----TLPAHSDPVTAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLXTL 170

Query: 840 -HPHSSDVRSVRFSPGAHYLLTGSYDMKIKVTD 871
               +  V  V+FSP   Y+L  + D  +K+ D
Sbjct: 171 IDDDNPPVSFVKFSPNGKYILAATLDNTLKLWD 269
>12574
          Length = 521

 Score = 40.8 bits (94), Expect = 0.003,   Method: Composition-based stats.
 Identities = 27/112 (24%), Positives = 57/112 (50%), Gaps = 1/112 (0%)
 Frame = +3

Query: 752 LSGHTGHILAL-YTWSGWMIASGSQDKTVRFWDLRVPSCVRVVGTTFHGTGSAVASVAVD 810
           L+GHT  + A+ ++ +G  +AS S DK ++ W        +    T  G    ++ VA  
Sbjct: 174 LAGHTKALSAVKFSPNGDWLASSSADKLIKIWGAYDGKFEK----TIAGHKLGLSDVAWS 341

Query: 811 PSGRLLATGQEDSSCMLYDIRGGRMVQSYHPHSSDVRSVRFSPGAHYLLTGS 862
              +LL +  +D +  +++   G+ +++   HS+ V    F+P ++ +++GS
Sbjct: 342 SDSKLLCSASDDKTLKIWEFSTGKCMKTLKGHSNYVFCCNFNPQSNLIVSGS 497

 Score = 35.0 bits (79), Expect = 0.15,   Method: Composition-based stats.
 Identities = 21/78 (26%), Positives = 37/78 (47%)
 Frame = +3

Query: 842 HSSDVRSVRFSPGAHYLLTGSYDMKIKVTDLQGDLTKQLPLMVVGEHKDKVIQCRWHTQD 901
           H+  + +V+FSP   +L + S D  IK+    G    +    + G HK  +    W +  
Sbjct: 183 HTKALSAVKFSPNGDWLASSSADKLIKI---WGAYDGKFEKTIAG-HKLGLSDVAWSSDS 350

Query: 902 LSFLSSSADRTVTLWTYS 919
               S+S D+T+ +W +S
Sbjct: 351 KLLCSASDDKTLKIWEFS 404
>14555
          Length = 627

 Score = 40.8 bits (94), Expect = 0.003,   Method: Composition-based stats.
 Identities = 27/78 (34%), Positives = 38/78 (48%), Gaps = 2/78 (2%)
 Frame = -2

Query: 789 CVRVVGTTFHGTGSAVASVAVDPSGRLLATGQEDSSCMLYDIRGGRMVQSYHPHS--SDV 846
           CV++    F G  + +  V   PSG   ATG +D++C L+D+R  R V  Y   S     
Sbjct: 623 CVQM----FEGHEADINCVRFYPSGDAFATGSDDATCRLFDLRADREVNCYRKESIIFGC 456

Query: 847 RSVRFSPGAHYLLTGSYD 864
            +V FS     LL G Y+
Sbjct: 455 NAVDFSVSGR-LLFGGYE 405

 Score = 33.9 bits (76), Expect = 0.27,   Method: Composition-based stats.
 Identities = 15/40 (37%), Positives = 21/40 (52%)
 Frame = -2

Query: 836 VQSYHPHSSDVRSVRFSPGAHYLLTGSYDMKIKVTDLQGD 875
           VQ +  H +D+  VRF P      TGS D   ++ DL+ D
Sbjct: 620 VQMFEGHEADINCVRFYPSGDAFATGSDDATCRLFDLRAD 501
>19498
          Length = 903

 Score = 39.3 bits (90), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 53/219 (24%), Positives = 85/219 (38%), Gaps = 26/219 (11%)
 Frame = -1

Query: 661 HKGSIYCVAWSPCGQLLATGSNDKYVKVLPFN-----AETCNATGPDLE-------FSMH 708
           H G + CV WS  G+ LA+G +DK + +   +      ++  +    LE          H
Sbjct: 789 HLGCVNCVRWSENGKFLASGGDDKLIMIWQISRGFGSGKSFGSNVTILEHWRSVATLRGH 610

Query: 709 DGTIRDLAFMEGPEXXXXXXXXXXXXDCNIYTTDCQR-GQGLHALSGHTGHILALYTWS- 766
            G + DLA+   P+            D  I   +  +  + +  + GH G +  + TW  
Sbjct: 609 AGDVLDLAW--SPQDLWLASCSV---DNTIVVWNALKFSEQVAVIRGHAGMVKGV-TWDP 448

Query: 767 -GWMIASGSQDKTVRFW---DLR----VPSCVRVVGTTFHGTGSAVASVAVDPSGRLL-- 816
            G  +AS S DKT+R W   D +    V SC +  G T H     V  +   P G  +  
Sbjct: 447 VGRYLASQSDDKTLRVWRTSDWKEETCVKSCFKECGGTTH-----VLRLNWSPDGNHVVS 283

Query: 817 --ATGQEDSSCMLYDIRGGRMVQSYHPHSSDVRSVRFSP 853
             A      +  + +  G      +  H   +  VRF+P
Sbjct: 282 AHAMNNAXPTAQIIERNGWGTSLDFVGHRKAITVVRFNP 166

 Score = 30.0 bits (66), Expect = 4.4,   Method: Compositional matrix adjust.
 Identities = 26/115 (22%), Positives = 47/115 (40%), Gaps = 14/115 (12%)
 Frame = -1

Query: 769 MIASGSQDKTVRFWDL-RVPSCVRVVGT------------TFHGTGSAVASVAVDPSGRL 815
            +ASG  DK +  W + R     +  G+            T  G    V  +A  P    
Sbjct: 744 FLASGGDDKLIMIWQISRGFGSGKSFGSNVTILEHWRSVATLRGHAGDVLDLAWSPQDLW 565

Query: 816 LATGQEDSSCMLYD-IRGGRMVQSYHPHSSDVRSVRFSPGAHYLLTGSYDMKIKV 869
           LA+   D++ ++++ ++    V     H+  V+ V + P   YL + S D  ++V
Sbjct: 564 LASCSVDNTIVVWNALKFSEQVAVIRGHAGMVKGVTWDPVGRYLASQSDDKTLRV 400
>03044
          Length = 1952

 Score = 38.9 bits (89), Expect = 0.010,   Method: Compositional matrix adjust.
 Identities = 26/100 (26%), Positives = 46/100 (46%), Gaps = 1/100 (1%)
 Frame = -2

Query: 604  LEDTQAVRAVAFHPSGSLYAVGSNSKTLRVCAYPEKMDASAHDNPKQPVVRFKRNKHHKG 663
            L   +A   V + P  + +AVGS+++ + V  Y E+       + K+P+         + 
Sbjct: 1531 LRINRAATCVKWSPEENKFAVGSSARLISVSYYEEEHRWWVSKHIKKPI---------RS 1379

Query: 664  SIYCVAWSPCGQLLATGSNDKYVKVLP-FNAETCNATGPD 702
            ++ C+ W P   L+A GS D   +V   +  ET    GP+
Sbjct: 1378 TVTCLDWHPNNILIAAGSTDFKARVFSGYVKETEAKPGPN 1259
>21105
          Length = 650

 Score = 38.9 bits (89), Expect = 0.010,   Method: Compositional matrix adjust.
 Identities = 26/102 (25%), Positives = 43/102 (42%), Gaps = 4/102 (3%)
 Frame = +1

Query: 772 SGSQDKTVRFWDLRVPSCVRVVGTTFHGTGSAVASVAVDPSGRLLATGQEDSSCMLYDIR 831
           +  +D+ +RF+D      +  +         +V S+AVDP+G  L +G  D S  L+++ 
Sbjct: 115 TAHEDRHIRFFDNNTGKLIHAMVAHL----DSVTSLAVDPNGLYLLSGSHDCSIRLWNLD 282

Query: 832 GGRMVQSYHPH----SSDVRSVRFSPGAHYLLTGSYDMKIKV 869
               VQ    H       +  V F P   Y+ +   D   KV
Sbjct: 283 SKTCVQEITSHRKKFDESIHDVAFHPQKPYIASAGADALAKV 408

 Score = 38.1 bits (87), Expect = 0.016,   Method: Compositional matrix adjust.
 Identities = 23/95 (24%), Positives = 45/95 (47%), Gaps = 1/95 (1%)
 Frame = +1

Query: 735 DCNIYTTDCQRGQGLHALSGHTGHILALYTW-SGWMIASGSQDKTVRFWDLRVPSCVRVV 793
           D +I   D   G+ +HA+  H   + +L    +G  + SGS D ++R W+L   +CV+ +
Sbjct: 127 DRHIRFFDNNTGKLIHAMVAHLDSVTSLAVDPNGLYLLSGSHDCSIRLWNLDSKTCVQEI 306

Query: 794 GTTFHGTGSAVASVAVDPSGRLLATGQEDSSCMLY 828
            +       ++  VA  P    +A+   D+   ++
Sbjct: 307 TSHRKKFDESIHDVAFHPQKPYIASAGADALAKVF 411
>34005
          Length = 456

 Score = 36.6 bits (83), Expect = 0.043,   Method: Composition-based stats.
 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 5/77 (6%)
 Frame = +1

Query: 749 LHALSGHTGHILALYTWSGW---MIASG--SQDKTVRFWDLRVPSCVRVVGTTFHGTGSA 803
           LH L+ H   + A+  W  W   M+A+G  + D+ +RFW+    +CV+ V T      S 
Sbjct: 226 LHTLTSHQAAVKAV-AWCPWQTRMLATGGGTNDRHIRFWNTNTGACVKAVDTQ-----SQ 387

Query: 804 VASVAVDPSGRLLATGQ 820
           V SV      R L +G 
Sbjct: 388 VCSVLWCKEHRELVSGH 438
>12806
          Length = 961

 Score = 36.6 bits (83), Expect = 0.048,   Method: Compositional matrix adjust.
 Identities = 26/131 (19%), Positives = 55/131 (41%), Gaps = 1/131 (0%)
 Frame = +3

Query: 735 DCNIYTTDCQRGQGLHALSGHTGHILAL-YTWSGWMIASGSQDKTVRFWDLRVPSCVRVV 793
           D  +   D ++G        HT  +L + ++     IASG +DK ++ W++ +  C   V
Sbjct: 228 DATLRLWDIKKGSTTSRFINHTRDVLTVAFSPDNRQIASGGRDKNLKIWNI-MGECKYTV 404

Query: 794 GTTFHGTGSAVASVAVDPSGRLLATGQEDSSCMLYDIRGGRMVQSYHPHSSDVRSVRFSP 853
               H           D    ++ +   D +  ++D     +  ++  H + + ++  S 
Sbjct: 405 DANAHTDWVTCVRFHQDTKNPIVVSASNDKTIKVWDNHTMTLKNTFVGHKAQITALDMS- 581

Query: 854 GAHYLLTGSYD 864
             +YL++GS D
Sbjct: 582 -TNYLVSGSKD 611

 Score = 33.9 bits (76), Expect = 0.32,   Method: Compositional matrix adjust.
 Identities = 19/68 (27%), Positives = 33/68 (48%)
 Frame = +3

Query: 769 MIASGSQDKTVRFWDLRVPSCVRVVGTTFHGTGSAVASVAVDPSGRLLATGQEDSSCMLY 828
           ++ S S DKT++ WD    +    +  TF G  + +   A+D S   L +G +D   M +
Sbjct: 468 IVVSASNDKTIKVWD----NHTMTLKNTFVGHKAQI--TALDMSTNYLVSGSKDGIAMTW 629

Query: 829 DIRGGRMV 836
           ++  G  V
Sbjct: 630 NVAEGSFV 653
>31474
          Length = 403

 Score = 35.8 bits (81), Expect = 0.072,   Method: Composition-based stats.
 Identities = 20/59 (33%), Positives = 30/59 (50%), Gaps = 2/59 (3%)
 Frame = -3

Query: 661 HKGSIYCVAWSPCGQLLATGSNDKYVKVLPFNAE--TCNATGPDLEFSMHDGTIRDLAF 717
           H    +CVAW+P G LLA+  +DK +K+     +   C +T  D     H  T+R L +
Sbjct: 308 HDEHAWCVAWNPTGTLLASCGSDKIIKIWGKEGDNWVCKSTLTD----AHTRTVRSLGW 144

 Score = 32.7 bits (73), Expect = 0.74,   Method: Composition-based stats.
 Identities = 22/71 (30%), Positives = 34/71 (47%), Gaps = 3/71 (4%)
 Frame = -3

Query: 807 VAVDPSGRLLATGQEDSSCMLYDIRGGRMVQS---YHPHSSDVRSVRFSPGAHYLLTGSY 863
           VA +P+G LLA+   D    ++   G   V        H+  VRS+ +SP  +YL + S+
Sbjct: 287 VAWNPTGTLLASCGSDKIIKIWGKEGDNWVCKSTLTDAHTRTVRSLGWSPCGNYLSSASF 108

Query: 864 DMKIKVTDLQG 874
           D    V   +G
Sbjct: 107 DATTAVWSRKG 75

 Score = 31.6 bits (70), Expect = 1.7,   Method: Composition-based stats.
 Identities = 24/90 (26%), Positives = 39/90 (43%)
 Frame = -3

Query: 599 VCINTLEDTQAVRAVAFHPSGSLYAVGSNSKTLRVCAYPEKMDASAHDNPKQPVVRFKRN 658
           VC  +  D  A   VA++P+G+L A   + K +++            DN    V +    
Sbjct: 326 VCCLSAHDEHA-WCVAWNPTGTLLASCGSDKIIKIWG-------KEGDNW---VCKSTLT 180

Query: 659 KHHKGSIYCVAWSPCGQLLATGSNDKYVKV 688
             H  ++  + WSPCG  L++ S D    V
Sbjct: 179 DAHTRTVRSLGWSPCGNYLSSASFDATTAV 90
>15337
          Length = 860

 Score = 35.8 bits (81), Expect = 0.086,   Method: Compositional matrix adjust.
 Identities = 38/145 (26%), Positives = 53/145 (36%)
 Frame = -1

Query: 548 GSTNHIPFHEDSPCGSQNSSEHSVIKPSPGDSSGNLSRSKGEEDDKSKKQFVCINTLEDT 607
           GS     ++E+ PCG Q    +   K   G S   +   K +       ++V       T
Sbjct: 479 GSGQMYAYNEELPCG-QTPPNYQPFKQGEGYS---VFTCKTKSTRNPLYRWVV-----GT 327

Query: 608 QAVRAVAFHPSGSLYAVGSNSKTLRVCAYPEKMDASAHDNPKQPVVRFKRNKHHKGSIYC 667
            A+   AF P     AV      LRV  Y   M+                 K + G + C
Sbjct: 326 GAISEFAFSPCSRYLAVVGQDGHLRVFNY-NSMEL------------IGTMKSYFGGLLC 186

Query: 668 VAWSPCGQLLATGSNDKYVKVLPFN 692
           V WSP G+ + TG  D  V V  F+
Sbjct: 185 VCWSPDGKYIVTGGEDDLVTVWSFH 111
>21921
          Length = 1341

 Score = 35.8 bits (81), Expect = 0.091,   Method: Compositional matrix adjust.
 Identities = 22/75 (29%), Positives = 38/75 (50%), Gaps = 1/75 (1%)
 Frame = -1

Query: 754 GHTGHILALYT-WSGWMIASGSQDKTVRFWDLRVPSCVRVVGTTFHGTGSAVASVAVDPS 812
           GHTG + ++    +G  + SGS D T+RFW++    C++ +       G  V SVA +P+
Sbjct: 489 GHTGIVRSICPDPTGQWLVSGSDDGTIRFWEVSSGRCMKTL-----QVGGCVTSVAWNPN 325

Query: 813 GRLLATGQEDSSCML 827
             L       ++ +L
Sbjct: 324 PSLCVVAATLNTTVL 280
>27681
          Length = 465

 Score = 35.4 bits (80), Expect = 0.095,   Method: Compositional matrix adjust.
 Identities = 28/103 (27%), Positives = 43/103 (41%), Gaps = 9/103 (8%)
 Frame = +2

Query: 614 AFHPSGSLYAVGSNSKTLRVCAYPEKMDASAHDNPKQPVVRFKRNKH-----HKGSIYCV 668
           A++P+  L A GS   T R+      M +   +N  Q V+R    K          +  +
Sbjct: 14  AWNPTNDLLASGSGDSTARIW----NMTSETPNNANQLVLRHCIQKGGTEVPSNKDVTSL 181

Query: 669 AWSPCGQLLATGSNDKYVKVLPFNAETCNA----TGPDLEFSM 707
            W+  G LLATGS D Y ++   +    N      GP+L   +
Sbjct: 182 DWNSEGTLLATGSYDGYARLWRTDGHLVNTLGQHKGPNLRLEV 310

 Score = 32.0 bits (71), Expect = 1.0,   Method: Compositional matrix adjust.
 Identities = 23/75 (30%), Positives = 33/75 (44%), Gaps = 11/75 (14%)
 Frame = +2

Query: 769 MIASGSQDKTVRFWD-----------LRVPSCVRVVGTTFHGTGSAVASVAVDPSGRLLA 817
           ++ASGS D T R W+           L +  C++  GT    +   V S+  +  G LLA
Sbjct: 35  LLASGSGDSTARIWNMTSETPNNANQLVLRHCIQKGGTEV-PSNKDVTSLDWNSEGTLLA 211

Query: 818 TGQEDSSCMLYDIRG 832
           TG  D    L+   G
Sbjct: 212 TGSYDGYARLWRTDG 256

 Score = 31.6 bits (70), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 12/33 (36%), Positives = 19/33 (57%)
 Frame = +2

Query: 665 IYCVAWSPCGQLLATGSNDKYVKVLPFNAETCN 697
           ++  AW+P   LLA+GS D   ++    +ET N
Sbjct: 2   VFICAWNPTNDLLASGSGDSTARIWNMTSETPN 100
>19140
          Length = 573

 Score = 35.4 bits (80), Expect = 0.12,   Method: Compositional matrix adjust.
 Identities = 27/84 (32%), Positives = 35/84 (41%), Gaps = 1/84 (1%)
 Frame = -3

Query: 749 LHALSGHTGHILAL-YTWSGWMIASGSQDKTVRFWDLRVPSCVRVVGTTFHGTGSAVASV 807
           L  L GHT ++ AL     G    SGS D T+R W L    CV     TF      V ++
Sbjct: 508 LMKLKGHTDNVKALVLNRDGTQCLSGSSDGTIRLWSLGQQRCV----ATFRVHDEGVWAL 341

Query: 808 AVDPSGRLLATGQEDSSCMLYDIR 831
             + S   L +G  D      DI+
Sbjct: 340 QANESFTTLYSGGRDHQVWATDIK 269
>35607
          Length = 475

 Score = 35.0 bits (79), Expect = 0.13,   Method: Compositional matrix adjust.
 Identities = 28/106 (26%), Positives = 46/106 (43%)
 Frame = +2

Query: 811 PSGRLLATGQEDSSCMLYDIRGGRMVQSYHPHSSDVRSVRFSPGAHYLLTGSYDMKIKVT 870
           P G  L TG  D++   +D+R GR +Q  H  SS + S+ + P   +L  G     ++V 
Sbjct: 8   PDGTKLWTGGLDNTVRSWDLREGRQLQQ-HDFSSQIFSLGYCPTGDWLAVGMESSNVEVL 184

Query: 871 DLQGDLTKQLPLMVVGEHKDKVIQCRWHTQDLSFLSSSADRTVTLW 916
                   QL L     H+  V+  ++      F+S+  D  +  W
Sbjct: 185 HHSKPDKYQLHL-----HESCVLSLKFAYCGKWFVSTGKDNLLNAW 307

 Score = 34.3 bits (77), Expect = 0.26,   Method: Compositional matrix adjust.
 Identities = 38/148 (25%), Positives = 61/148 (41%), Gaps = 1/148 (0%)
 Frame = +2

Query: 770 IASGSQDKTVRFWDLRVPSCVRVVGTTFHGTGSAVASVAVDPSGRLLATGQEDSSCMLYD 829
           + +G  D TVR WDLR    ++      H   S + S+   P+G  LA G E S+  +  
Sbjct: 23  LWTGGLDNTVRSWDLREGRQLQQ-----HDFSSQIFSLGYCPTGDWLAVGMESSNVEVLH 187

Query: 830 IRGGRMVQSYHPHSSDVRSVRFSP-GAHYLLTGSYDMKIKVTDLQGDLTKQLPLMVVGEH 888
                  Q  H H S V S++F+  G  ++ TG  ++      L    T     +   + 
Sbjct: 188 HSKPDKYQ-LHLHESCVLSLKFAYCGKWFVSTGKDNL------LNAWRTPYGASIFQSKE 346

Query: 889 KDKVIQCRWHTQDLSFLSSSADRTVTLW 916
              V+ C     D   ++ S D+  TL+
Sbjct: 347 SSSVLSCDIAADDKYIVTGSGDKKATLY 430
>15780
          Length = 735

 Score = 35.0 bits (79), Expect = 0.13,   Method: Composition-based stats.
 Identities = 17/51 (33%), Positives = 27/51 (52%), Gaps = 1/51 (1%)
 Frame = -1

Query: 735 DCNIYTTDCQRGQGLHALSGHTGHILAL-YTWSGWMIASGSQDKTVRFWDL 784
           D  +   D   G  +  L+ HT  + AL ++  G ++ASG  D ++R WDL
Sbjct: 711 DHTVIVWDIASGTAVAHLTAHTDTVYALCFSRDGTVLASGGMDNSIRLWDL 559
>01598
          Length = 1545

 Score = 33.9 bits (76), Expect = 0.30,   Method: Compositional matrix adjust.
 Identities = 46/218 (21%), Positives = 85/218 (38%), Gaps = 14/218 (6%)
 Frame = +1

Query: 579  SSGNLSRSKGEEDDKSKKQFVCINTLEDTQAVRA--VAFHPSGSLYAVGSNSKTLRVCAY 636
            SS  LSR + + +     Q +     +  + ++A  +++ P  +  AVG++  ++ V   
Sbjct: 883  SSAVLSRGEKKANAIDITQKIGAVNSDQVKGLKATELSWSPDQNAAAVGTDEGSVYVVTI 1062

Query: 637  PEKMDASAHDNPKQPVVRFKRNKHHKGSIYCVAWSPCGQLLATGSNDKYVKVLPF----- 691
             + +   A    +Q ++   R  H + +    A SPC   LA   ND+ + V+       
Sbjct: 1063 -QDLKIVAAIRTQQKLINCVR-WHPRLTDQSPAGSPCCHWLAAAGNDQVIHVVDLASVFA 1236

Query: 692  ----NAETCNATGPDLEFSMHDGTIRDLAFMEGPEXXXXXXXXXXXXDCNIYTTDCQRGQ 747
                + ET        E S H   + D+++                 D   +  D Q+G 
Sbjct: 1237 EREGDKETSLILTSLRELSGHSQRVTDMSW----SPHHDARLVSVGYDAEAFVWDVQKGT 1404

Query: 748  GLHALSGHTGHILALYTWSGW---MIASGSQDKTVRFW 782
             L    GH G +L    +SG    ++ +G  D +V  W
Sbjct: 1405 ALAQFKGHMGRLLTC-QFSGLDPDLVMTGGSDASVHVW 1515

 Score = 29.6 bits (65), Expect = 5.4,   Method: Compositional matrix adjust.
 Identities = 31/124 (25%), Positives = 56/124 (45%), Gaps = 17/124 (13%)
 Frame = +1

Query: 767 GWMIASGSQDKTVRFWDL---------RVPSCVRVVGTTFHGTGSAVASVAVDPSGRLLA 817
           G +IA+GS+D+T+R W L         ++P+  R  G T       +A   +  +   L 
Sbjct: 100 GCLIATGSKDRTIRVWTLSQGKQIFMKKLPNQRREAGDTGSRFKVWLAIHWLKSNPEQLV 279

Query: 818 TGQEDSSCMLYDIR--GGRMVQS-----YHPHSSDVRSVRFS-PGAHYLLTGSYDMKIKV 869
           +       +L+ +R   G+  Q+     Y PH   V ++  S P +  L T + D ++ +
Sbjct: 280 SSSSGGDLLLWSLRYTKGQAYQTFQTSDYRPHMRPVFNICASGPDSKTLCTFAQDRQVVL 459

Query: 870 TDLQ 873
            DL+
Sbjct: 460 WDLE 471
>37180
          Length = 681

 Score = 33.1 bits (74), Expect = 0.48,   Method: Compositional matrix adjust.
 Identities = 15/37 (40%), Positives = 22/37 (59%)
 Frame = +1

Query: 749 LHALSGHTGHILALYTWSGWMIASGSQDKTVRFWDLR 785
           ++   GHT  + +    SG  + SGS D+TVR WD+R
Sbjct: 127 VNVFQGHTQPVTSAVFASGDKVVSGSDDRTVRVWDMR 237
>01462
          Length = 995

 Score = 32.7 bits (73), Expect = 0.68,   Method: Compositional matrix adjust.
 Identities = 19/52 (36%), Positives = 28/52 (53%), Gaps = 1/52 (1%)
 Frame = +2

Query: 735 DCNIYTTDCQRGQGLHALSGHTGHILALYTWS-GWMIASGSQDKTVRFWDLR 785
           D  I+  D + GQ L+A+ GH  +I  +   +      S S+D TVR WD+R
Sbjct: 260 DRKIHVWDIEAGQYLNAMEGHKDYIHKVVMKNDAQECVSASEDGTVRMWDIR 415
>30727
          Length = 402

 Score = 32.7 bits (73), Expect = 0.71,   Method: Compositional matrix adjust.
 Identities = 20/98 (20%), Positives = 37/98 (37%), Gaps = 13/98 (13%)
 Frame = +1

Query: 768 WMIASGSQDKTVRFWDLRVPSCVRVVGTT-FHGTGSAVASVAVDP----------SGRLL 816
           W + SG  D  +  WD   P C+        H T S  ++  ++P           G ++
Sbjct: 103 WEVLSGGMDSRLVHWDFSKPKCLNQFNMQELHSTTSDASAYMINPPFIHHLAKNSDGSII 282

Query: 817 ATGQEDSSCMLYDIRGGRMVQSY--HPHSSDVRSVRFS 852
           A   E+    +++     + + +  H H   V  V F+
Sbjct: 283 ACALENGLIAVFNSTAKHLQEKFCLHAHQQGVSQVHFT 396
>25880
          Length = 423

 Score = 32.3 bits (72), Expect = 0.93,   Method: Composition-based stats.
 Identities = 22/63 (34%), Positives = 33/63 (52%)
 Frame = +2

Query: 660 HHKGSIYCVAWSPCGQLLATGSNDKYVKVLPFNAETCNATGPDLEFSMHDGTIRDLAFME 719
            HK  +  VA+    + + TGSN+K V+V  FN E  +A  P+L +  H G I+   +  
Sbjct: 50  QHKHIVKSVAFDNSSENIVTGSNEKLVRV--FNLEQPDAE-PEL-YGGHTGAIKRALYAS 217

Query: 720 GPE 722
           G E
Sbjct: 218 GSE 226
>26939
          Length = 388

 Score = 32.3 bits (72), Expect = 0.99,   Method: Composition-based stats.
 Identities = 18/54 (33%), Positives = 25/54 (46%), Gaps = 8/54 (14%)
 Frame = +2

Query: 767 GWMIASGSQDKTVRFWDLRVPSCVRVV--------GTTFHGTGSAVASVAVDPS 812
           G  + S S DKT+R WDLR   C++ +           FH     V S +VD +
Sbjct: 2   GKYLVSASDDKTIRVWDLRNKRCMKTLYAHQHFCTSIDFHKAHPYVISGSVDQT 163
>20662
          Length = 1220

 Score = 31.2 bits (69), Expect = 1.7,   Method: Compositional matrix adjust.
 Identities = 28/83 (33%), Positives = 36/83 (43%), Gaps = 1/83 (1%)
 Frame = +2

Query: 835 MVQSYHPHSSDVRSVRFSPGAHYLLTGSYDMKIKVTDLQGDLTKQLPLMVVGEHKDKVIQ 894
           M+ S   H     SV  +    + L+ SYD  IKV +   DLT    L     H D V  
Sbjct: 362 MLSSACEHDDMTASVSINSDXSHYLSASYDHGIKVWNT--DLTS---LYTYRAHSDIVWD 526

Query: 895 CRWH-TQDLSFLSSSADRTVTLW 916
            + H T+   FLS S D  + LW
Sbjct: 527 VQCHPTEPALFLSCSQDGKIVLW 595
>21164
          Length = 609

 Score = 31.2 bits (69), Expect = 2.2,   Method: Composition-based stats.
 Identities = 17/42 (40%), Positives = 25/42 (59%), Gaps = 3/42 (7%)
 Frame = -3

Query: 64  VLQFIQPLECMEKFDKKRF---RYIILKQKFLEALCVNNAMS 102
           VLQF+   +CM K+DK+ F    +I +  KF +   VNN +S
Sbjct: 538 VLQFLIYSQCMNKYDKQAFCPVVFIHMS*KFNQDFIVNNLIS 413
>08355
          Length = 498

 Score = 30.8 bits (68), Expect = 2.4,   Method: Composition-based stats.
 Identities = 14/36 (38%), Positives = 19/36 (52%), Gaps = 4/36 (11%)
 Frame = -1

Query: 886 GEHKDKVIQCRWHTQD----LSFLSSSADRTVTLWT 917
           G+H D V Q RW   D    ++F S S+D  +  WT
Sbjct: 420 GKHTDPVWQVRWQKDDSDNNMNFFSISSDGRIVHWT 313
>25400
          Length = 462

 Score = 30.8 bits (68), Expect = 2.8,   Method: Composition-based stats.
 Identities = 20/62 (32%), Positives = 29/62 (46%)
 Frame = +3

Query: 857 YLLTGSYDMKIKVTDLQGDLTKQLPLMVVGEHKDKVIQCRWHTQDLSFLSSSADRTVTLW 916
           Y+ +G     I + DL   LT ++   + G H+  V    WH    + +SSS D TV  W
Sbjct: 3   YVYSGCATGTILIYDL---LTGRVVRKLDGGHRSCVRDVSWHPYTNTLISSSWDGTVGKW 173

Query: 917 TY 918
            Y
Sbjct: 174 DY 179
>21763
          Length = 923

 Score = 30.8 bits (68), Expect = 2.8,   Method: Compositional matrix adjust.
 Identities = 23/89 (25%), Positives = 43/89 (48%)
 Frame = +1

Query: 827 LYDIRGGRMVQSYHPHSSDVRSVRFSPGAHYLLTGSYDMKIKVTDLQGDLTKQLPLMVVG 886
           +Y++   + V+    +   + S+   PG   ++ GSYD K    DL  DL+ + P  ++ 
Sbjct: 394 IYNLLTQQFVKKLQTNCKWISSMDVHPGGDNVIIGSYDCKSCWFDL--DLSTK-PYKILR 564

Query: 887 EHKDKVIQCRWHTQDLSFLSSSADRTVTL 915
            HK  V    +H +   F S+S D ++ +
Sbjct: 565 HHKRAVRHVSYHHRYPLFASASDDGSIIV 651
>18320
          Length = 450

 Score = 30.8 bits (68), Expect = 2.9,   Method: Compositional matrix adjust.
 Identities = 27/87 (31%), Positives = 36/87 (41%), Gaps = 12/87 (13%)
 Frame = -2

Query: 802 SAVASVAVDPSGRLLATGQEDSSCMLYDIRGGRMVQSYHPHSSDVRSVRFSPGAH----- 856
           +AV  V +  +G+LLA G  D    L D+          P S     +     AH     
Sbjct: 281 AAVDVVHLMQNGQLLAAGSRDRYLTLLDLTK---YDPARPKSKKDMQLHCIDKAHSGWIW 111

Query: 857 -------YLLTGSYDMKIKVTDLQGDL 876
                  +L TGS+D KIKV DL  D+
Sbjct: 110 CMASLNQHLYTGSWDTKIKVWDLGQDM 30
>31384
          Length = 474

 Score = 30.4 bits (67), Expect = 3.3,   Method: Compositional matrix adjust.
 Identities = 17/57 (29%), Positives = 25/57 (43%)
 Frame = -1

Query: 656 KRNKHHKGSIYCVAWSPCGQLLATGSNDKYVKVLPFNAETCNATGPDLEFSMHDGTI 712
           K  + H G +  V WS  G  + T S DK  KV   N+  C      ++ + HD  +
Sbjct: 153 KAQQTHTGPVLDVDWSDDGTKVFTASCDKTAKVWDLNSNQC------MQIAQHDAPV 1

 Score = 30.0 bits (66), Expect = 4.3,   Method: Compositional matrix adjust.
 Identities = 19/53 (35%), Positives = 28/53 (52%), Gaps = 3/53 (5%)
 Frame = -1

Query: 744 QRGQGL-HALSGHTGHILALYTWS--GWMIASGSQDKTVRFWDLRVPSCVRVV 793
           Q GQ +  A   HTG +L +  WS  G  + + S DKT + WDL    C+++ 
Sbjct: 174 QSGQTIPKAQQTHTGPVLDV-DWSDDGTKVFTASCDKTAKVWDLNSNQCMQIA 19
>31054
          Length = 392

 Score = 30.4 bits (67), Expect = 3.6,   Method: Compositional matrix adjust.
 Identities = 23/94 (24%), Positives = 36/94 (38%)
 Frame = -2

Query: 746 GQGLHALSGHTGHILALYTWSGWMIASGSQDKTVRFWDLRVPSCVRVVGTTFHGTGSAVA 805
           G  +  LSGH   I  L   S  ++ SG+ + T+  WD R        G  F    +AV 
Sbjct: 319 GNFIQNLSGHNAIINTLAVNSDGVLVSGADNGTMHLWDWR-------TGYNFQRIHAAVQ 161

Query: 806 SVAVDPSGRLLATGQEDSSCMLYDIRGGRMVQSY 839
             ++D      A   + S   L      + ++ Y
Sbjct: 160 PGSLDSESGFFACTFDQSESRLITAEADKTIKVY 59
>12960
          Length = 550

 Score = 30.4 bits (67), Expect = 3.8,   Method: Compositional matrix adjust.
 Identities = 19/55 (34%), Positives = 24/55 (43%), Gaps = 1/55 (1%)
 Frame = +2

Query: 735 DCNIYTTDCQRGQGLHALSGHTGHILAL-YTWSGWMIASGSQDKTVRFWDLRVPS 788
           D  +   D   GQ L     H G +  + +     +I SGS D TVR WD R  S
Sbjct: 362 DKTVVLFDVASGQALRKYRDHAGTVNCVKFNEESTVILSGSLDNTVRAWDTRSRS 526
>05420
          Length = 371

 Score = 29.6 bits (65), Expect = 5.1,   Method: Composition-based stats.
 Identities = 12/21 (57%), Positives = 15/21 (71%)
 Frame = -2

Query: 459 GVNQEDGPDQQQNLTEQFLNR 479
           G  Q+ GP + QNLT+Q LNR
Sbjct: 319 GPKQQHGPKETQNLTKQILNR 257
>17298
          Length = 476

 Score = 29.3 bits (64), Expect = 7.4,   Method: Composition-based stats.
 Identities = 17/44 (38%), Positives = 21/44 (47%), Gaps = 1/44 (2%)
 Frame = -1

Query: 746 GQGLHALSGHTGHILAL-YTWSGWMIASGSQDKTVRFWDLRVPS 788
           GQ L     H G +  + +     +I SGS D TVR WD R  S
Sbjct: 242 GQALRKYRDHAGTVNCVKFNEESTVILSGSLDNTVRAWDTRSRS 111
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|29611654|ref|NP_776113.1| hypothetical protein
LOC216551 [Mus musculus]
         (172 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

03566                                                                  86   7e-18
09957                                                                  74   4e-14
30609                                                                  32   0.10 
08011                                                                  32   0.14 
>03566
          Length = 1893

 Score = 86.3 bits (212), Expect = 7e-18,   Method: Compositional matrix adjust.
 Identities = 46/128 (35%), Positives = 73/128 (57%)
 Frame = +3

Query: 44  IKGGMRPGKKVLVMGIVDLNPESFAISLTCGDSEDPPADVAIELKAVFTDRQLLRNSCIS 103
           I GGM PG+ V + G+   N + F I+L  G  E    D+A+          ++RNS  +
Sbjct: 12  IPGGMTPGRMVAISGVPFPNAQGFTINLQSGTYEG--CDIALHFNVRIPINTIVRNSFQN 185

Query: 104 GERGEEQSAIPYFPFIPDQPFRVEILCEHPRFRVFVDGHQLFDFYHRIQTLSAIDTIKIN 163
           G  G E+   P FPF+P+  F + IL E   F+V V+   L +F HR+  L A++T++++
Sbjct: 186 GGWGGEERNAPCFPFMPNANFDIMILAEPQAFKVAVNNQHLLEFRHRL-PLQAVNTMRVD 362

Query: 164 GDLQITKL 171
           GDL+IT++
Sbjct: 363 GDLRITQV 386
>09957
          Length = 865

 Score = 73.6 bits (179), Expect = 4e-14,   Method: Compositional matrix adjust.
 Identities = 41/118 (34%), Positives = 60/118 (50%)
 Frame = +3

Query: 35  RLIVPFCGHIKGGMRPGKKVLVMGIVDLNPESFAISLTCGDSEDPPADVAIELKAVFTDR 94
           RL  PF   + G + PG  V++ G  D + + FAI+L CG S D   D+A      F D 
Sbjct: 258 RLDEPFTDSVPGNLEPGNWVVMYGAPDDDADGFAINLQCGPSSDS-DDIAFHFNPRFNDG 434

Query: 95  QLLRNSCISGERGEEQSAIPYFPFIPDQPFRVEILCEHPRFRVFVDGHQLFDFYHRIQ 152
           + +RN+   G+ G E+   PYFPF P+  F +  +      RVFV+  +  D+  RI 
Sbjct: 435 ETVRNTREGGDWGGEERDQPYFPFEPEDRFELAYVMLPHGIRVFVNRRRYIDYNFRIN 608
>30609
          Length = 411

 Score = 32.3 bits (72), Expect = 0.10,   Method: Compositional matrix adjust.
 Identities = 17/54 (31%), Positives = 27/54 (50%)
 Frame = +2

Query: 97  LRNSCISGERGEEQSAIPYFPFIPDQPFRVEILCEHPRFRVFVDGHQLFDFYHR 150
           +RN+   G+  +E+    +FPF  +  F +  +  H   RVFV+     DF HR
Sbjct: 5   IRNTREGGDWQDEERDQDFFPFEEEDRFELAFVILHHGIRVFVNHRHFTDFKHR 166
>08011
          Length = 731

 Score = 32.0 bits (71), Expect = 0.14,   Method: Compositional matrix adjust.
 Identities = 21/72 (29%), Positives = 34/72 (47%), Gaps = 3/72 (4%)
 Frame = +2

Query: 84  AIELKAVFTDRQL---LRNSCISGERGEEQSAIPYFPFIPDQPFRVEILCEHPRFRVFVD 140
           +  + A  T+RQ    ++     G RG++    PYFPF P+  F +  +      RVFV+
Sbjct: 32  STSIPASMTERQCATHVKAGTGEGRRGDQ----PYFPFEPEDRFELAYVMLPHGIRVFVN 199

Query: 141 GHQLFDFYHRIQ 152
             +  D+  RI 
Sbjct: 200 RRRYIDYNFRIN 235
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|85662410|ref|NP_034120.2| cytoplasmic linker 2
isoform a [Mus musculus]
         (1047 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

18826                                                                  89   8e-18
26691                                                                  83   5e-16
10547                                                                  80   3e-15
20779                                                                  80   5e-15
20604                                                                  65   1e-10
02533                                                                  29   9.0  
>18826
          Length = 490

 Score = 89.4 bits (220), Expect = 8e-18,   Method: Composition-based stats.
 Identities = 37/71 (52%), Positives = 51/71 (71%)
 Frame = +3

Query: 80  FVVGERVWVNGVKPGVVQYLGETQFAPGQWAGVVLDDPVGKNDGAVGGVRYFECPALQGI 139
           F++G+RVWV G++ G + Y+GET FAPG WAG+VLD+P GK      G RYF+C   +GI
Sbjct: 252 FIIGQRVWVGGLRSGQIAYIGETHFAPGDWAGIVLDEPNGKKRWMRFGQRYFQCEPKRGI 431

Query: 140 FTRPSKLTRQP 150
           F+R ++LT  P
Sbjct: 432 FSRLTRLTTYP 464

 Score = 73.9 bits (180), Expect = 3e-13,   Method: Composition-based stats.
 Identities = 32/65 (49%), Positives = 44/65 (67%)
 Frame = +3

Query: 222 LGDRVLVGGTKTGVVRYVGETDFAKGEWCGVELDEPLGKNDGAVAGTRYFQCPPKFGLFA 281
           +G RV VGG ++G + Y+GET FA G+W G+ LDEP GK      G RYFQC PK G+F+
Sbjct: 258 IGQRVWVGGLRSGQIAYIGETHFAPGDWAGIVLDEPNGKKRWMRFGQRYFQCEPKRGIFS 437

Query: 282 PIHKV 286
            + ++
Sbjct: 438 RLTRL 452
>26691
          Length = 395

 Score = 83.2 bits (204), Expect = 5e-16,   Method: Compositional matrix adjust.
 Identities = 36/72 (50%), Positives = 49/72 (68%)
 Frame = +2

Query: 216 GDKDLHLGDRVLVGGTKTGVVRYVGETDFAKGEWCGVELDEPLGKNDGAVAGTRYFQCPP 275
           G + L +G R+L+ G K GV+R+VG+T  A G WCG+EL +  G +DG V G RYF C P
Sbjct: 116 GAEKLTVGKRILISGVKPGVLRFVGQTSLAPGYWCGIELFDASGLHDGEVDGRRYFTCKP 295

Query: 276 KFGLFAPIHKVI 287
             G+FAP+ KV+
Sbjct: 296 FRGIFAPLDKVV 331

 Score = 73.9 bits (180), Expect = 3e-13,   Method: Compositional matrix adjust.
 Identities = 30/60 (50%), Positives = 42/60 (70%)
 Frame = +2

Query: 81  VVGERVWVNGVKPGVVQYLGETQFAPGQWAGVVLDDPVGKNDGAVGGVRYFECPALQGIF 140
            VG+R+ ++GVKPGV++++G+T  APG W G+ L D  G +DG V G RYF C   +GIF
Sbjct: 131 TVGKRILISGVKPGVLRFVGQTSLAPGYWCGIELFDASGLHDGEVDGRRYFTCKPFRGIF 310
>10547
          Length = 856

 Score = 80.5 bits (197), Expect = 3e-15,   Method: Composition-based stats.
 Identities = 35/61 (57%), Positives = 41/61 (67%)
 Frame = +2

Query: 232 KTGVVRYVGETDFAKGEWCGVELDEPLGKNDGAVAGTRYFQCPPKFGLFAPIHKVIRIGF 291
           + G VRYVGETDF  G W G++ DEP GKNDG+VAG RYF+C PK+G F     V    F
Sbjct: 2   RRGTVRYVGETDFKPGMWVGIQYDEPHGKNDGSVAGKRYFECQPKYGGFVKPSNVEVGDF 181

Query: 292 P 292
           P
Sbjct: 182 P 184

 Score = 71.2 bits (173), Expect = 2e-12,   Method: Composition-based stats.
 Identities = 29/53 (54%), Positives = 36/53 (67%)
 Frame = +2

Query: 94  GVVQYLGETQFAPGQWAGVVLDDPVGKNDGAVGGVRYFECPALQGIFTRPSKL 146
           G V+Y+GET F PG W G+  D+P GKNDG+V G RYFEC    G F +PS +
Sbjct: 8   GTVRYVGETDFKPGMWVGIQYDEPHGKNDGSVAGKRYFECQPKYGGFVKPSNV 166
>20779
          Length = 490

 Score = 80.1 bits (196), Expect = 5e-15,   Method: Composition-based stats.
 Identities = 40/66 (60%), Positives = 46/66 (69%)
 Frame = +3

Query: 238 YVGETDFAKGEWCGVELDEPLGKNDGAVAGTRYFQCPPKFGLFAPIHKVIRIGFPSTSPA 297
           Y+GET FA G WCGVELDE  GKNDG V G RYF+C P+FG+F PI KV      S SP+
Sbjct: 3   YLGETQFAPGNWCGVELDEGSGKNDGTVDGIRYFECKPRFGVFVPIAKV------SLSPS 164

Query: 298 KAKKTK 303
             KKT+
Sbjct: 165 -TKKTR 179

 Score = 73.9 bits (180), Expect = 3e-13,   Method: Composition-based stats.
 Identities = 38/71 (53%), Positives = 48/71 (67%), Gaps = 1/71 (1%)
 Frame = +3

Query: 98  YLGETQFAPGQWAGVVLDDPVGKNDGAVGGVRYFECPALQGIFTRPSKLTRQPTAEGSG- 156
           YLGETQFAPG W GV LD+  GKNDG V G+RYFEC    G+F   +K++  P+ + +  
Sbjct: 3   YLGETQFAPGNWCGVELDEGSGKNDGTVDGIRYFECKPRFGVFVPIAKVSLSPSTKKTRL 182

Query: 157 SDTHSVESLTA 167
           S T S ESLT+
Sbjct: 183 SRTGSRESLTS 215
>20604
          Length = 678

 Score = 65.5 bits (158), Expect = 1e-10,   Method: Composition-based stats.
 Identities = 31/62 (50%), Positives = 35/62 (56%)
 Frame = +3

Query: 100 GETQFAPGQWAGVVLDDPVGKNDGAVGGVRYFECPALQGIFTRPSKLTRQPTAEGSGSDT 159
           G   FA G W GV LD P GKNDG+V G+RYF C    GIF RP KL      +GS   T
Sbjct: 114 GTCAFAVGNWIGVELDQPEGKNDGSVKGIRYFNCRGRHGIFVRPDKLIWDKKRKGSRKST 293

Query: 160 HS 161
            +
Sbjct: 294 QA 299

 Score = 58.2 bits (139), Expect(2) = 5e-09,   Method: Composition-based stats.
 Identities = 30/67 (44%), Positives = 40/67 (59%), Gaps = 4/67 (5%)
 Frame = +3

Query: 240 GETDFAKGEWCGVELDEPLGKNDGAVAGTRYFQCPPKFGLFAPIHKVI----RIGFPSTS 295
           G   FA G W GVELD+P GKNDG+V G RYF C  + G+F    K+I    R G   ++
Sbjct: 114 GTCAFAVGNWIGVELDQPEGKNDGSVKGIRYFNCRGRHGIFVRPDKLIWDKKRKGSRKST 293

Query: 296 PAKAKKT 302
            A A+++
Sbjct: 294 QAGARRS 314

 Score = 21.6 bits (44), Expect(2) = 5e-09,   Method: Composition-based stats.
 Identities = 8/12 (66%), Positives = 10/12 (83%)
 Frame = +1

Query: 229 GGTKTGVVRYVG 240
           G +KTG VR+VG
Sbjct: 82  GPSKTGXVRFVG 117
>02533
          Length = 961

 Score = 29.3 bits (64), Expect = 9.0,   Method: Compositional matrix adjust.
 Identities = 24/61 (39%), Positives = 33/61 (54%), Gaps = 9/61 (14%)
 Frame = +2

Query: 174 SGTATPPLTGRVIPLRESVLNSSVKTGNESGS-----NLSDSGS----VKRGDKDLHLGD 224
           +G+AT P+ G  +PL+ SVL+  V +G ES S     + SDS S    V+R    LH   
Sbjct: 695 TGSATVPVPGEALPLQRSVLH--VDSGPESRSAHARPHSSDSPSVETLVQRPHSSLHQAT 868

Query: 225 R 225
           R
Sbjct: 869 R 871
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|86262142|ref|NP_063922.2| RNA binding motif protein
14 [Mus musculus]
         (669 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

00029                                                                  89   8e-18
25632                                                                  66   5e-11
16427                                                                  54   2e-07
17775                                                                  52   6e-07
20169                                                                  50   3e-06
28652                                                                  49   6e-06
17681                                                                  48   1e-05
10194                                                                  47   2e-05
00738                                                                  46   5e-05
11687                                                                  45   1e-04
01065                                                                  45   1e-04
13457                                                                  45   1e-04
31265                                                                  43   4e-04
04988                                                                  42   7e-04
23720                                                                  42   8e-04
28605                                                                  42   0.001
29364                                                                  40   0.003
19868                                                                  40   0.003
19824                                                                  38   0.013
26197                                                                  37   0.031
02809                                                                  37   0.033
03744                                                                  35   0.069
03406                                                                  35   0.077
32386                                                                  35   0.099
20488                                                                  35   0.10 
15994                                                                  35   0.13 
00817                                                                  35   0.14 
03000                                                                  34   0.16 
12506                                                                  34   0.19 
16016                                                                  34   0.21 
25691                                                                  33   0.41 
03903                                                                  33   0.49 
30786                                                                  32   0.63 
30672                                                                  30   3.3  
31618                                                                  29   4.9  
03200                                                                  28   8.3  
>00029
          Length = 2204

 Score = 88.6 bits (218), Expect = 8e-18,   Method: Compositional matrix adjust.
 Identities = 39/77 (50%), Positives = 53/77 (68%)
 Frame = -3

Query: 78   TWKIFVGNVSAACTSQELRSLFERRGRVIECDVVKDYAFVHMEKEADAKAAIAQLNGKEV 137
            T KIF+GN+      +ELR+LFE+ G V ECDV+K++ FVHM K+ +A  AI+ LNG  +
Sbjct: 2139 TIKIFIGNLGDDTDPEELRALFEKYGSVAECDVLKNFGFVHMVKKGEADDAISNLNGYNI 1960

Query: 138  KGKRINVELSTKGQKKG 154
             G+R+ VELST   K G
Sbjct: 1959 GGQRMRVELSTGAGKGG 1909

 Score = 71.2 bits (173), Expect = 1e-12,   Method: Compositional matrix adjust.
 Identities = 35/71 (49%), Positives = 47/71 (66%)
 Frame = -3

Query: 1    MKIFVGNVDGADTTPEELAALFAPYGTVMSCAVMKQFAFVHMRENAGAVRAIEALHGHEL 60
            +KIF+GN+ G DT PEEL ALF  YG+V  C V+K F FVHM +   A  AI  L+G+ +
Sbjct: 2136 IKIFIGNL-GDDTDPEELRALFEKYGSVAECDVLKNFGFVHMVKKGEADDAISNLNGYNI 1960

Query: 61   RPGRALVVEMS 71
              G+ + VE+S
Sbjct: 1959 G-GQRMRVELS 1930
>25632
          Length = 864

 Score = 65.9 bits (159), Expect = 5e-11,   Method: Compositional matrix adjust.
 Identities = 35/72 (48%), Positives = 47/72 (65%), Gaps = 8/72 (11%)
 Frame = -2

Query: 91  TSQELRSL------FERRGRVIECDVVKDYAFVHMEKEADAKAAIAQLNGKEVKGKRINV 144
           TS  +R+L       E+ G V ECDV+K+Y FVHM  +++A AAI  LNG  +KG+R+ V
Sbjct: 749 TSVMIRNLMTFVCCLEKYGTVEECDVLKNYGFVHMPTKSEASAAITNLNGYNIKGQRMRV 570

Query: 145 ELST--KGQKKG 154
           ELST  +G  KG
Sbjct: 569 ELSTNKRGNPKG 534

 Score = 43.1 bits (100), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 20/54 (37%), Positives = 30/54 (55%)
 Frame = -2

Query: 18  LAALFAPYGTVMSCAVMKQFAFVHMRENAGAVRAIEALHGHELRPGRALVVEMS 71
                  YGTV  C V+K + FVHM   + A  AI  L+G+ ++ G+ + VE+S
Sbjct: 719 FVCCLEKYGTVEECDVLKNYGFVHMPTKSEASAAITNLNGYNIK-GQRMRVELS 561
>16427
          Length = 1313

 Score = 53.9 bits (128), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 25/79 (31%), Positives = 44/79 (55%), Gaps = 8/79 (10%)
 Frame = +1

Query: 80  KIFVGNVSAACTSQELRSLFERRGRVIECDVVKD--------YAFVHMEKEADAKAAIAQ 131
           K+FVG ++     + L   F + GR+ E  V++D        + FV  E   DA+ A+  
Sbjct: 139 KLFVGGLAEEIDEKVLEREFSKFGRITESMVIRDKVRQVSRGFGFVTYENPMDAEEAVKH 318

Query: 132 LNGKEVKGKRINVELSTKG 150
           ++GKE+ GK+++VE + +G
Sbjct: 319 MDGKEILGKKLHVEDAVRG 375
>17775
          Length = 1282

 Score = 52.4 bits (124), Expect = 6e-07,   Method: Compositional matrix adjust.
 Identities = 41/160 (25%), Positives = 76/160 (47%), Gaps = 18/160 (11%)
 Frame = -2

Query: 3    IFVGNVDGADTTPEELAALFAPYGTVMSCAVMKQ--------FAFVHMRENAGAVRAIEA 54
            ++VG++   D T   L   F+  G V+S  V +         +A+V+ ++ A A RA++ 
Sbjct: 1188 LYVGDLH-PDVTEAMLFEKFSTAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDT 1012

Query: 55   LHGHELRPGRALVVEMSR----PRPLNTWKIFVGNVSAACTSQELRSLFERRGRVIECDV 110
            ++   ++ GR + +  S+     R      +F+ N+     ++ L   F   G ++ C +
Sbjct: 1011 MNFDTVK-GRPIRIMWSQRDPSVRKSGVGNVFIKNLDKTIDNKALYDTFSAFGNILSCKI 835

Query: 111  VKD------YAFVHMEKEADAKAAIAQLNGKEVKGKRINV 144
              D      Y FVH E E  A+ AI ++NG  + GK++ V
Sbjct: 834  ACDEQGSKGYGFVHFETEEAARQAIDKVNGMLLNGKKVYV 715
>20169
          Length = 1364

 Score = 50.1 bits (118), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 29/84 (34%), Positives = 43/84 (51%), Gaps = 4/84 (4%)
 Frame = -1

Query: 69   EMSRPRPLN-TWKIFVGNVSAACTSQELRSLFERRGRVIECDVVKD---YAFVHMEKEAD 124
            EMSR R  +   K++VG +   C  QEL   F + G +    V +    +AFV  E   D
Sbjct: 1103 EMSRHRDFSLDCKVYVGELGHGCAKQELEDKFAKYGPLKNVWVARRPAGFAFVEFEDNRD 924

Query: 125  AKAAIAQLNGKEVKGKRINVELST 148
            A+ A+  L+G  + G+R  VE+S 
Sbjct: 923  AEDAVQALDGARINGRRARVEMSN 852
>28652
          Length = 918

 Score = 48.9 bits (115), Expect = 6e-06,   Method: Compositional matrix adjust.
 Identities = 30/108 (27%), Positives = 51/108 (47%), Gaps = 8/108 (7%)
 Frame = -2

Query: 2   KIFVGNVDGADTTPEELAALFAPYGTVMSCAVM--------KQFAFVHMRENAGAVRAIE 53
           ++F G +   D   +EL  LF   GT+    +M        + + FV       A  A++
Sbjct: 728 EVFCGKI-PRDIFEDELIPLFEDCGTIWDLRLMMDPVSNLNRGYCFVTYTTKEAAAEAVK 552

Query: 54  ALHGHELRPGRALVVEMSRPRPLNTWKIFVGNVSAACTSQELRSLFER 101
              G+E+R G+ L V +S P      ++FVGN+  + T +E+   FE+
Sbjct: 551 QHDGYEIRKGKKLKVNISIP----NLRLFVGNIPKSKTKEEILKEFEK 420

 Score = 44.7 bits (104), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 39/162 (24%), Positives = 66/162 (40%), Gaps = 18/162 (11%)
 Frame = -2

Query: 1   MKIFVGNVDGADTTPEELAALFAPYGTVMSCAVM----------KQFAFVHMRENAGAVR 50
           +++FVGN+  + T  E L         +M   V           + FAF+    +  A  
Sbjct: 488 LRLFVGNIPKSKTKEEILKEFEKHSEGLMDVIVYGSADNPKLKNRGFAFLEYDTHKNASA 309

Query: 51  AIEALHGHELRPGRALVV-------EMSRPRPLNTWKI-FVGNVSAACTSQELRSLFERR 102
           A         R  +  V+       E      ++  K+ +V N++   T  +L+  F   
Sbjct: 308 AKRRFTTGRFRVWQCDVIVDWADLQEEPNEETMSKVKVLYVRNLTGDVTEDDLKEKFGAY 129

Query: 103 GRVIECDVVKDYAFVHMEKEADAKAAIAQLNGKEVKGKRINV 144
           G+V     +KDY FVH E   DA  A+  L+G+++    I+V
Sbjct: 128 GKVERVKKIKDYGFVHYEDREDALKALDDLHGEKIGNLEIDV 3

 Score = 34.3 bits (77), Expect = 0.19,   Method: Compositional matrix adjust.
 Identities = 24/88 (27%), Positives = 41/88 (46%), Gaps = 9/88 (10%)
 Frame = -2

Query: 70  MSRPRPLNTWKIFVGNVSAACTSQELRSLFERRGRVIECDVVKD--------YAFVHMEK 121
            + P+P +  ++F G +       EL  LFE  G + +  ++ D        Y FV    
Sbjct: 758 WTDPQPGSGHEVFCGKIPRDIFEDELIPLFEDCGTIWDLRLMMDPVSNLNRGYCFVTYTT 579

Query: 122 EADAKAAIAQLNGKEV-KGKRINVELST 148
           +  A  A+ Q +G E+ KGK++ V +S 
Sbjct: 578 KEAAAEAVKQHDGYEIRKGKKLKVNISI 495
>17681
          Length = 964

 Score = 48.1 bits (113), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 26/77 (33%), Positives = 41/77 (53%), Gaps = 8/77 (10%)
 Frame = +2

Query: 81  IFVGNVSAACTSQELRSLFERRGRVIECDVVKD--------YAFVHMEKEADAKAAIAQL 132
           IFVG++S    ++ LR  F   G +  C +V+D        YAFV   K+A+A+ AI  +
Sbjct: 38  IFVGDLSPEIETETLREAFAPFGEISNCRIVRDPQTMKSKGYAFVSFVKKAEAENAIQAM 217

Query: 133 NGKEVKGKRINVELSTK 149
           NG+ +  + I    ST+
Sbjct: 218 NGQWIGSRSIRTNWSTR 268
>10194
          Length = 1278

 Score = 47.0 bits (110), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 47/178 (26%), Positives = 83/178 (46%), Gaps = 35/178 (19%)
 Frame = -3

Query: 3   IFVGNVDGADTTPEELAALFAPYGTVMS----CA-------------VMKQF-------- 37
           +FVGNV    T  ++LA LF  +G + +    CA             + K F        
Sbjct: 706 VFVGNV-PLKTDKKKLARLFKQFGKIENVRFRCAPVGDPTTKKRVAVITKDFHEKRHNIS 530

Query: 38  AFVHMRENAGAVRAIEALHGHELRPGRALVVEMSRP--RPLNTWKIFVGNVSAACTSQEL 95
           A++  +E+  A +A+  L+GH +  G  L V+ ++   + L+   +FVGN+      + +
Sbjct: 529 AYICFKEDEAAKQAL-TLNGHVI-DGLHLRVDSAKLSLKNLDKRSVFVGNLPFDIEEESV 356

Query: 96  RSLFERRGRVIECDVVKD--------YAFVHMEKEADAKAAIAQLNGKEVKGKRINVE 145
           RS FE  G V    VV+D          ++ + K AD+ +   +LN  E++ ++I V+
Sbjct: 355 RSHFEDCGDVENIRVVRDRKTNLGKGICYI-LFKSADSVSLALKLNNSELEKRQIRVQ 185
>00738
          Length = 1559

 Score = 46.2 bits (108), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 23/71 (32%), Positives = 46/71 (64%), Gaps = 3/71 (4%)
 Frame = -2

Query: 80   KIFVGNVSAACTSQELRSLFERRGRVIECDVVKD---YAFVHMEKEADAKAAIAQLNGKE 136
            +I VG++S++ +++E+R  F+R G +I+  + +     AFV    E DA+ AI +++G+ 
Sbjct: 1264 RIHVGSLSSSTSTREIREEFKRFGDIIDLWMPRTQPTIAFVVYRYEEDAEKAIRRMDGES 1085

Query: 137  VKGKRINVELS 147
            + G+R+ V L+
Sbjct: 1084 MHGRRVRVSLA 1052
>11687
          Length = 676

 Score = 45.1 bits (105), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 37/130 (28%), Positives = 58/130 (44%), Gaps = 17/130 (13%)
 Frame = +3

Query: 1   MKIFVGNVDGADTTPEELAALFAPYGTVMSCAVM--------KQFAFVHMRENAGAVRAI 52
           +K+FVG +   +    EL  +F  YG V S  ++        K   FV       A+ A 
Sbjct: 150 IKMFVGQI-PRNMDENELRKMFEDYGPVHSLNILRDKNTGQSKGCCFVTFFTRKAALDAQ 326

Query: 53  EALHGHELRPGRALVVEMSRP---------RPLNTWKIFVGNVSAACTSQELRSLFERRG 103
            ALH  +  P     V+M +P         R +   K+FVG +S   +  ++R LFE  G
Sbjct: 327 NALHNVKTMPMMHHPVQM-KPADSEKRNGERNVEERKLFVGMLSKKLSENDVRMLFESFG 503

Query: 104 RVIECDVVKD 113
            + +C V++D
Sbjct: 504 SIDDCTVLRD 533
>01065
          Length = 1033

 Score = 45.1 bits (105), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 23/71 (32%), Positives = 46/71 (64%), Gaps = 3/71 (4%)
 Frame = +2

Query: 80  KIFVGNVSAACTSQELRSLFERRGRVIECDVVKD---YAFVHMEKEADAKAAIAQLNGKE 136
           +I VG++S++ +++E+R  F+R G +I+  + +     AFV    E DA+ AI +++G+ 
Sbjct: 17  RIHVGSLSSSTSTREIREEFKRFGDIIDLWMPRTQPTIAFVVYRYEEDAEKAIRRMDGES 196

Query: 137 VKGKRINVELS 147
           + G+R+ V L+
Sbjct: 197 MHGRRVRVSLA 229
>13457
          Length = 4857

 Score = 44.7 bits (104), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 28/79 (35%), Positives = 42/79 (53%), Gaps = 9/79 (11%)
 Frame = -1

Query: 2    KIFVGNVDGADTTPEELAALFAPYGTVMSCAVM-------KQFAFVHMRENAGAVRAIEA 54
            K+FVG ++    T E++  LF PYG +  C ++       K  AFV    ++ A  AI A
Sbjct: 3405 KLFVGMLN-KQQTEEDVRQLFHPYGAIEECTILRDQNGNSKGCAFVKYSTHSEAQAAINA 3229

Query: 55   LHGHELRPG--RALVVEMS 71
            LHG +  PG   +LVV+ +
Sbjct: 3228 LHGSQTMPGASSSLVVKFA 3172

 Score = 41.2 bits (95), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 21/64 (32%), Positives = 36/64 (56%), Gaps = 7/64 (10%)
 Frame = -1

Query: 80   KIFVGNVSAACTSQELRSLFERRGRVIECDVVKD-------YAFVHMEKEADAKAAIAQL 132
            K+FVG ++   T +++R LF   G + EC +++D        AFV     ++A+AAI  L
Sbjct: 3405 KLFVGMLNKQQTEEDVRQLFHPYGAIEECTILRDQNGNSKGCAFVKYSTHSEAQAAINAL 3226

Query: 133  NGKE 136
            +G +
Sbjct: 3225 HGSQ 3214

 Score = 29.6 bits (65), Expect = 3.7,   Method: Compositional matrix adjust.
 Identities = 13/33 (39%), Positives = 21/33 (63%)
 Frame = -2

Query: 114  YAFVHMEKEADAKAAIAQLNGKEVKGKRINVEL 146
            + FV  +  A A+AAI  +NG ++  KR+ V+L
Sbjct: 2294 FGFVSFDNPASAQAAIQAMNGFQIGMKRLKVQL 2196
>31265
          Length = 540

 Score = 42.7 bits (99), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 40/138 (28%), Positives = 61/138 (44%), Gaps = 16/138 (11%)
 Frame = +2

Query: 37  FAFVHMRENAGAVRAIEALHGHELRPGRA------LVVEMSRPR------PLNTWKIF-V 83
           FAFV    +  A     A+   +L PGR       + V+ + P        ++  KI  V
Sbjct: 8   FAFVEYTSHRAA-----AMARRKLIPGRIQLWGHQIAVDWAEPEQDVDEDTMSQVKILXV 172

Query: 84  GNVSAACTSQELRSLFERR--GRVIE-CDVVKDYAFVHMEKEADAKAAIAQLNGKEVKGK 140
            N+    T + L+ +F R   GR IE    ++DYAFVH     DA  A+   +G  ++G 
Sbjct: 173 RNLMLTTTEETLKDVFSRAAGGREIERVKKIRDYAFVHFRSREDAIKAMDVTDGSTIEGS 352

Query: 141 RINVELSTKGQKKGPALA 158
           ++ V L+    K    LA
Sbjct: 353 QVEVVLAKPVDKTDIRLA 406
>04988
          Length = 705

 Score = 42.0 bits (97), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 19/66 (28%), Positives = 36/66 (54%)
 Frame = -3

Query: 80  KIFVGNVSAACTSQELRSLFERRGRVIECDVVKDYAFVHMEKEADAKAAIAQLNGKEVKG 139
           ++++G +      +++   F   GRV +  +   Y FV  E   DA  A+ +LNGK++ G
Sbjct: 649 RVYIGRLPYQAREKDIERFFRGYGRVNDIMLKNGYGFVEFEDFRDADDAVYELNGKDLCG 470

Query: 140 KRINVE 145
           +R+ +E
Sbjct: 469 ERVIIE 452
>23720
          Length = 739

 Score = 42.0 bits (97), Expect = 8e-04,   Method: Compositional matrix adjust.
 Identities = 19/66 (28%), Positives = 36/66 (54%)
 Frame = -1

Query: 80  KIFVGNVSAACTSQELRSLFERRGRVIECDVVKDYAFVHMEKEADAKAAIAQLNGKEVKG 139
           ++++G +      +++   F   GRV +  +   Y FV  E   DA  A+ +LNGK++ G
Sbjct: 682 RVYIGRLPYQAREKDIERFFRGYGRVNDIMLKNGYGFVEFEDFRDADDAVYELNGKDLCG 503

Query: 140 KRINVE 145
           +R+ +E
Sbjct: 502 ERVIIE 485
>28605
          Length = 697

 Score = 41.6 bits (96), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 19/58 (32%), Positives = 32/58 (55%), Gaps = 1/58 (1%)
 Frame = -3

Query: 2   KIFVGNVDGADTTPEELAALFAPYGTVMSCAV-MKQFAFVHMRENAGAVRAIEALHGH 58
           ++FV N+   +T+  EL  LF+ YG V+   V   ++ FV         RA+EA++G+
Sbjct: 566 RVFVANLSSDETSEAELQELFSKYGNVLDTLVHHNRYGFVQFSTEEEGRRAVEAMNGY 393

 Score = 41.2 bits (95), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 24/74 (32%), Positives = 42/74 (56%), Gaps = 2/74 (2%)
 Frame = -3

Query: 73  PRPLNTWKIFVGNVSAACTSQ-ELRSLFERRGRVIECDVVKD-YAFVHMEKEADAKAAIA 130
           P+ LN+ ++FV N+S+  TS+ EL+ LF + G V++  V  + Y FV    E + + A+ 
Sbjct: 584 PKFLNS-RVFVANLSSDETSEAELQELFSKYGNVLDTLVHHNRYGFVQFSTEEEGRRAVE 408

Query: 131 QLNGKEVKGKRINV 144
            +NG     K++  
Sbjct: 407 AMNGYMFYRKKLKC 366
>29364
          Length = 1126

 Score = 40.4 bits (93), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 20/56 (35%), Positives = 30/56 (53%)
 Frame = +1

Query: 90  CTSQELRSLFERRGRVIECDVVKDYAFVHMEKEADAKAAIAQLNGKEVKGKRINVE 145
              ++L   F+  GR  +  +   Y FV  E   DA  A+ +LNGKE+ G+R+ VE
Sbjct: 1   VRERDLERFFKGYGRTRDILIKNGYGFVEFEDYRDADDAVYELNGKELLGERVVVE 168
>19868
          Length = 434

 Score = 40.0 bits (92), Expect = 0.003,   Method: Composition-based stats.
 Identities = 35/117 (29%), Positives = 55/117 (47%), Gaps = 13/117 (11%)
 Frame = +2

Query: 2   KIFVGNVDGADTTPEELAALFAPYGTVMSCAVMKQ--------FAFVHMRENAGA----V 49
           K+FVG +    T+PE L   F  +G +    VMK         F F+   + A       
Sbjct: 2   KMFVGGLSW-QTSPESLRDYFNKFGEITEVMVMKDPTTRRSRGFGFITFGDPASVDKVLA 178

Query: 50  RAIEALHGHELRPGRALVVEMSRPRPLN-TWKIFVGNVSAACTSQELRSLFERRGRV 105
           +A   L G ++ P  A     + PR +  T KIFVG +SA  T +++++ FE+ G +
Sbjct: 179 QATHELDGKKIDPKVAF-PRRAHPRMVTRTKKIFVGGLSAPTTLEDVKNYFEQFGPI 346
>19824
          Length = 724

 Score = 37.7 bits (86), Expect = 0.013,   Method: Compositional matrix adjust.
 Identities = 21/60 (35%), Positives = 32/60 (53%)
 Frame = +1

Query: 103 GRVIECDVVKDYAFVHMEKEADAKAAIAQLNGKEVKGKRINVELSTKGQKKGPALAIQSG 162
           G V+E D+V ++ F H E   +AKAA   LNG    G  + VE+S    ++ P +  + G
Sbjct: 4   GNVVEFDIVSNFGFAHFEDANEAKAAADALNGFNYNGSDLRVEISHSKVRQRPGMGNREG 183
>26197
          Length = 1365

 Score = 36.6 bits (83), Expect = 0.031,   Method: Compositional matrix adjust.
 Identities = 23/72 (31%), Positives = 38/72 (52%), Gaps = 8/72 (11%)
 Frame = -2

Query: 80   KIFVGNVSAACTSQELRSLFERRGRVIECDVVKD--------YAFVHMEKEADAKAAIAQ 131
            KIFVG +S   +S+ LR  FE+ G V  C +  D        + FV + KEA    A+ +
Sbjct: 1295 KIFVGGLSWETSSKHLREYFEKFGEVTSCTLKTDLDSGKSRGFGFV-VFKEAVTVDAVVK 1119

Query: 132  LNGKEVKGKRIN 143
                +++G++I+
Sbjct: 1118 NKEHKLQGRKID 1083
>02809
          Length = 1475

 Score = 36.6 bits (83), Expect = 0.033,   Method: Compositional matrix adjust.
 Identities = 23/69 (33%), Positives = 34/69 (49%), Gaps = 4/69 (5%)
 Frame = -1

Query: 70   MSRPRPLN-TWKIFVGNVSAACTSQELRSLFERRGRVIECDVVK---DYAFVHMEKEADA 125
            MSR R  +   K++VG +   C  QEL   F + G +    V +    +AFV  E   DA
Sbjct: 1364 MSRHRDFSLDCKVYVGELGHGCAKQELEDKFAKYGPLKNVWVARRPAGFAFVEFEDNRDA 1185

Query: 126  KAAIAQLNG 134
            + A+  L+G
Sbjct: 1184 EDAVQALDG 1158
>03744
          Length = 3486

 Score = 35.4 bits (80), Expect = 0.069,   Method: Compositional matrix adjust.
 Identities = 20/75 (26%), Positives = 35/75 (46%), Gaps = 8/75 (10%)
 Frame = -1

Query: 80   KIFVGNVSAACTSQELRSLFERRGRVIECDVVKD--------YAFVHMEKEADAKAAIAQ 131
             +F+ ++      Q+L  +F   G V+   V  D        + FV  +    A+AAI  
Sbjct: 3213 NLFIYHLPQEFGDQDLMQMFMPFGNVVSAKVFIDKQTNLSKCFGFVSYDSPLAAQAAITS 3034

Query: 132  LNGKEVKGKRINVEL 146
            +NG ++  KR+ V+L
Sbjct: 3033 MNGFQIGMKRLKVQL 2989
>03406
          Length = 1292

 Score = 35.4 bits (80), Expect = 0.077,   Method: Compositional matrix adjust.
 Identities = 23/72 (31%), Positives = 36/72 (50%), Gaps = 8/72 (11%)
 Frame = +3

Query: 80  KIFVGNVSAACTSQELRSLFERRGRVIECDVVKD--------YAFVHMEKEADAKAAIAQ 131
           KIFVG +S    S+ LR  FE+ G V  C +  D        + FV   KEA    A+ +
Sbjct: 243 KIFVGGLSWETXSKHLREYFEKFGEVTSCTLKTDLDSGKSRGFGFVVF-KEAATVDAVVK 419

Query: 132 LNGKEVKGKRIN 143
               +++G++I+
Sbjct: 420 NKEHKLQGRKID 455
>32386
          Length = 674

 Score = 35.0 bits (79), Expect = 0.099,   Method: Compositional matrix adjust.
 Identities = 21/74 (28%), Positives = 36/74 (48%), Gaps = 12/74 (16%)
 Frame = +1

Query: 80  KIFVGNVSAACTSQELRSLFERRGRVIECDVVKD--------YAFVHMEKEADAKAAIA- 130
           K+F+G +S       LRS FE  G +++C V++D        + F+  +       A A 
Sbjct: 304 KLFIGGLSYETDEDSLRSHFETWGEIVDCIVMRDSNSKRSRGFGFITYKDAESIDQAQAN 483

Query: 131 ---QLNGKEVKGKR 141
              +++G+EV  KR
Sbjct: 484 RPHKIDGREVDTKR 525
>20488
          Length = 3281

 Score = 35.0 bits (79), Expect = 0.10,   Method: Compositional matrix adjust.
 Identities = 20/75 (26%), Positives = 35/75 (46%), Gaps = 8/75 (10%)
 Frame = +2

Query: 80   KIFVGNVSAACTSQELRSLFERRGRVIECDVVKD--------YAFVHMEKEADAKAAIAQ 131
             +F+ ++      Q+L  +F   G V+   V  D        + FV  +    A+AAI  
Sbjct: 2711 NLFIYHLPQEFGDQDLMQMFMPFGNVVSAKVFIDKQTNLSKCFGFVSYDSPLAAQAAITS 2890

Query: 132  LNGKEVKGKRINVEL 146
            +NG ++  KR+ V+L
Sbjct: 2891 MNGFQIGMKRLKVQL 2935
>15994
          Length = 891

 Score = 34.7 bits (78), Expect = 0.13,   Method: Compositional matrix adjust.
 Identities = 16/51 (31%), Positives = 28/51 (54%)
 Frame = +3

Query: 2   KIFVGNVDGADTTPEELAALFAPYGTVMSCAVMKQFAFVHMRENAGAVRAI 52
           ++FVGN++    + E++  +F  YG V   ++ K +AFV       A RA+
Sbjct: 306 RVFVGNLNTFTLSKEDVDRIFGAYGAVTGISMHKGYAFVQYNHPGEARRAV 458
>00817
          Length = 2606

 Score = 34.7 bits (78), Expect = 0.14,   Method: Compositional matrix adjust.
 Identities = 16/41 (39%), Positives = 21/41 (51%)
 Frame = -2

Query: 73   PRPLNTWKIFVGNVSAACTSQELRSLFERRGRVIECDVVKD 113
            P      K+F+G +        LRS FE+ G + EC VVKD
Sbjct: 2569 PNAERNRKVFIGGMHPDTDESSLRSYFEKYGDIRECIVVKD 2447
>03000
          Length = 778

 Score = 34.3 bits (77), Expect = 0.16,   Method: Compositional matrix adjust.
 Identities = 21/74 (28%), Positives = 36/74 (48%), Gaps = 12/74 (16%)
 Frame = +3

Query: 80  KIFVGNVSAACTSQELRSLFERRGRVIECDVVKD--------YAFVHMEKEADAKAAIA- 130
           K+F+G +S       LRS FE  G +++C V++D        + F+  +       A A 
Sbjct: 90  KLFIGGLSYETDEDSLRSHFETWGEIVDCIVMRDSNSKRSRGFGFITYKDAESIDQAQAN 269

Query: 131 ---QLNGKEVKGKR 141
              +++G+EV  KR
Sbjct: 270 RPHKIDGREVDTKR 311
>12506
          Length = 1056

 Score = 33.9 bits (76), Expect = 0.19,   Method: Compositional matrix adjust.
 Identities = 21/61 (34%), Positives = 34/61 (55%), Gaps = 1/61 (1%)
 Frame = -3

Query: 114 YAFVHMEKEADAKAAIAQLNGKEVKGKRINVELSTKGQ-KKGPALAIQSGDKTKKPGAGD 172
           +AF+  E   DA AAI  +N  E+ G+ I V L+   + K+G + A+ + D   +  AG+
Sbjct: 934 FAFIEFELAEDAAAAIDNMNESELFGRTIRVNLAKPMKVKEGASRAVWADDTWLQQHAGE 755

Query: 173 T 173
           T
Sbjct: 754 T 752
>16016
          Length = 1364

 Score = 33.9 bits (76), Expect = 0.21,   Method: Compositional matrix adjust.
 Identities = 15/34 (44%), Positives = 20/34 (58%)
 Frame = -2

Query: 80   KIFVGNVSAACTSQELRSLFERRGRVIECDVVKD 113
            K+F+G +        LRS FE+ G + EC VVKD
Sbjct: 1306 KVFIGGMHPDTDESSLRSYFEKYGDIRECIVVKD 1205
>25691
          Length = 768

 Score = 33.1 bits (74), Expect = 0.41,   Method: Compositional matrix adjust.
 Identities = 16/48 (33%), Positives = 26/48 (54%), Gaps = 8/48 (16%)
 Frame = -2

Query: 108 CDVVKD--------YAFVHMEKEADAKAAIAQLNGKEVKGKRINVELS 147
           C +++D        Y FV+ +++ DA  AI  LNG  ++ K I V L+
Sbjct: 431 CKLIRDKPTGQSLGYGFVNYKRQEDADKAIHTLNGLRLQNKTIKVSLA 288
>03903
          Length = 983

 Score = 32.7 bits (73), Expect = 0.49,   Method: Compositional matrix adjust.
 Identities = 31/118 (26%), Positives = 49/118 (41%), Gaps = 22/118 (18%)
 Frame = -1

Query: 59  ELRPGRALVVEMSRPRPLNTWK-------IFVGNVSAACTSQELRSLF--------ERRG 103
           ELR GR    EM        +K       +++ N+S   T ++L  +F        E   
Sbjct: 539 ELRKGRLSXREMEEISVFRNYKEGEPSRRLYIKNLSKQVTEEDLHWVFGRYVNWDKEEEK 360

Query: 104 RVIECDVVKD-----YAFVHMEKEADAKAAIAQLNGKEVKGKRINVEL--STKGQKKG 154
            + +  ++K+      AFV +  E  A+ A+   N    KGK I V    S K Q++G
Sbjct: 359 SIFDIRLMKEGRMKGQAFVTLGTEEQARKAVKDTNAFVFKGKPIAVHFARSAKQQEEG 186
>30786
          Length = 524

 Score = 32.3 bits (72), Expect = 0.63,   Method: Composition-based stats.
 Identities = 15/43 (34%), Positives = 22/43 (51%)
 Frame = +3

Query: 129 IAQLNGKEVKGKRINVELSTKGQKKGPALAIQSGDKTKKPGAG 171
           I  ++ +EVK K+  +    KGQ  G A+  Q G +   PG G
Sbjct: 339 INDMDAREVKNKKAYLNTDKKGQGLGAAVGPQVGPRVNTPGVG 467
>30672
          Length = 877

 Score = 30.0 bits (66), Expect = 3.3,   Method: Compositional matrix adjust.
 Identities = 17/73 (23%), Positives = 36/73 (49%), Gaps = 7/73 (9%)
 Frame = +3

Query: 80  KIFVGNVSAACTSQELRSLFERRGRVIEC-------DVVKDYAFVHMEKEADAKAAIAQL 132
           ++ + N++  C   ++RS F + G + E        D  + +AFV   +   A+ AI+ +
Sbjct: 408 RLIIRNLAFKCKEADIRSHFGKFGTISEVTIPLKQGDRSRGFAFVQFTEVKAAQKAISDM 587

Query: 133 NGKEVKGKRINVE 145
           NG  +  + + V+
Sbjct: 588 NGTAIMDRPVAVD 626
>31618
          Length = 716

 Score = 29.3 bits (64), Expect = 4.9,   Method: Compositional matrix adjust.
 Identities = 24/78 (30%), Positives = 38/78 (48%), Gaps = 12/78 (15%)
 Frame = +1

Query: 76  LNTWKIFVGNVSAACTSQELRSLFERRGRVIECDVVKD--------YAF-VHMEKEADAK 126
           + T K+FVG +S   T +ELR  F + G +   +V  D        +AF V    EA  +
Sbjct: 283 MMTEKLFVGGLSWETTEKELRDHFGKYGEIESINVKTDPQTGRSRGFAFIVFTNTEAIDQ 462

Query: 127 AAIAQ---LNGKEVKGKR 141
            + A+   +N K+V  K+
Sbjct: 463 VSAAEEHIINSKKVDPKK 516
>03200
          Length = 657

 Score = 28.5 bits (62), Expect = 8.3,   Method: Composition-based stats.
 Identities = 19/69 (27%), Positives = 32/69 (46%), Gaps = 2/69 (2%)
 Frame = -1

Query: 91  TSQELRSLFERRGRVIECDVVKDY--AFVHMEKEADAKAAIAQLNGKEVKGKRINVELST 148
           T   L+S F   G ++  ++ ++    FV  EK   A  AIA +NG  +     NV+L  
Sbjct: 456 TEDILKSAFSNFGNIVNINIERERNNGFVTFEKMESADQAIANMNGSMIS----NVQLKV 289

Query: 149 KGQKKGPAL 157
              ++ P+ 
Sbjct: 288 MMARRQPSF 262
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|13385084|ref|NP_079899.1| nipsnap homolog 3A [Mus
musculus]
         (247 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

06725                                                                  86   1e-17
08476                                                                  34   0.046
>06725
          Length = 739

 Score = 86.3 bits (212), Expect = 1e-17,   Method: Compositional matrix adjust.
 Identities = 43/125 (34%), Positives = 64/125 (51%), Gaps = 3/125 (2%)
 Frame = -1

Query: 27  TGPRQSNGTFYEFRTYFLKPSKTNEFLENFKNSVHLRTAHSEMIGYWTVEFGGRTNRVFH 86
            GP  S G+ YE R Y +KP     F +   +  HLR  +S+ IGYW  + GG    V H
Sbjct: 670 NGPESSQGSVYELRIYSIKPDMFGTFRQLMADKFHLRFPYSKPIGYWIADLGGIFQAV-H 494

Query: 87  IWKYDNFAHRTAVRKALAKDKEWQERFLIPNLAFIDKQEVEITYLVPWCKIGT---PPKE 143
           IW Y++ + R  +R+A+A D+EWQ+ F +  +  + + +  +  L P   I T   P   
Sbjct: 493 IWPYESVSERGRIRQAMAVDQEWQQEFFLKFMPCLIRMDNSMMVLSPGASINTDFAPSPT 314

Query: 144 GVYEL 148
             YEL
Sbjct: 313 AAYEL 299
>08476
          Length = 2241

 Score = 34.3 bits (77), Expect = 0.046,   Method: Compositional matrix adjust.
 Identities = 20/68 (29%), Positives = 31/68 (45%)
 Frame = -3

Query: 180  LVGVFHTEYGALNRVHVLWWNESADSRAAGRHWSHEDPRVVAAVRESVSYLESQQNTFLI 239
            + G F  + G    VH +W     ++R   R  + + P     V  +V  +   Q+  LI
Sbjct: 2224 VAGFFSQDGGTCIWVHHIWAYTDLETRKITREAAWQRPGWDECVAYTVPLIRHMQSRILI 2045

Query: 240  PTSFSPLK 247
            PT FSPL+
Sbjct: 2044 PTPFSPLQ 2021
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|161353502|ref|NP_033955.2| serine (or cysteine)
proteinase inhibitor, clade H, member 1 [Mus musculus]
         (417 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

06284                                                                  73   1e-17
22564                                                                  45   5e-05
17346                                                                  33   0.15 
28968                                                                  31   1.1  
>06284
          Length = 1414

 Score = 72.8 bits (177), Expect(2) = 1e-17,   Method: Compositional matrix adjust.
 Identities = 76/287 (26%), Positives = 133/287 (46%), Gaps = 19/287 (6%)
 Frame = +1

Query: 85  KATTASQAKAVLSAEKLRDEEVHTGLGELLRSLSNSTARNVTWKL---GSRLYGPSSVSF 141
           ++ TA Q K VL   K   +    G G  L  L  +  +     +     R+Y    ++ 
Sbjct: 226 RSDTAKQMKHVL---KWSXDLPQDGFGSYLSLLKEAEDKETPGYILVGAQRVYVDKKLTL 396

Query: 142 ADDFVRSSKQHYNCEHSKINF-RDKRSALQSINEWASQTTDGK----LPEVTKDVERTDG 196
             +F   +K+ +  E +  +F ++  +  ++IN+W S  T  K    LPE + D      
Sbjct: 397 KPEFSAVTKEKFASEATAADFAQNAEAERKTINDWISGKTRSKIQNLLPEGSLD--PLTA 570

Query: 197 ALLVNAMFFKPHWDEKFHHKMVDNRGFMVTRSYTVGVTMMHRTGLYNYYDDEKEKLQMVE 256
            +LV A++FK +W  KF  +  +   F   +   + V MM +   +++   +      VE
Sbjct: 571 MVLVQALYFKGNWMHKFDTRRTNPADFYSPQG-KITVNMMXQERKFSFSVSDDLDCAAVE 747

Query: 257 MPLA--------HKLSSLIILMPHHVEPLERLEKLLTKEQLKAWMGKMQKKAVAISLPKG 308
           +P A        H LS ++IL+P+  + + +LE+ LT ++L      M +  V   LP+ 
Sbjct: 748 LPYASNTQNASDHDLS-MLILLPNKRDGVVKLEEDLTAKKLDQLRSSMHQVKVDXQLPRF 924

Query: 309 VVEVTHDLQKHLAGLGLTEAIDKNKADLSRM-SGKK--DLYLASVFH 352
            +E +  L+K L+ LG+  A   N AD S + SG +   LY++ VFH
Sbjct: 925 SMESSVGLKKVLSSLGMPLAFG-NNADFSGLVSGPEADQLYISEVFH 1062

 Score = 35.0 bits (79), Expect(2) = 1e-17,   Method: Compositional matrix adjust.
 Identities = 16/38 (42%), Positives = 24/38 (63%), Gaps = 1/38 (2%)
 Frame = +2

Query: 381  FYADHPFIFLVRDNQSGSLLFIGRLVRPKGDKM-RDEL 417
            F ADHPF+  + D ++  +LF GR+ +P G    +DEL
Sbjct: 1157 FIADHPFLVFLVDKRADVVLFAGRVSKPNGAAAPKDEL 1270
>22564
          Length = 569

 Score = 45.1 bits (105), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 43/129 (33%), Positives = 63/129 (48%), Gaps = 7/129 (5%)
 Frame = +3

Query: 296 MQKKAVAISLPKGVVEVTHDLQKHLAGLGLTEAIDKNKADLSRM-SGKK--DLYLASVFH 352
           M +  V + LP+  +E +  L+K L+ LG+  A   N AD S + SG +   LY++ VFH
Sbjct: 3   MHQVKVDVQLPRFSMESSVGLKKVLSSLGMPLAFGNN-ADFSGLVSGPEADQLYISEVFH 179

Query: 353 ATAFEWDTEGNPFDQDIYGREELRSPKL---FYADHPFIFLVRDNQSGSLLFIGRLVRPK 409
               E + EG             RS  +   F ADHPF+  + D ++  +LF GR   P 
Sbjct: 180 KAMIEVNEEGAEAAAATAVVMMKRSIPIIHPFIADHPFLVFLVDKRADVVLFAGRXSNPS 359

Query: 410 GDKM-RDEL 417
           G    +DEL
Sbjct: 360 GAAAPKDEL 386
>17346
          Length = 980

 Score = 33.5 bits (75), Expect = 0.15,   Method: Compositional matrix adjust.
 Identities = 37/143 (25%), Positives = 61/143 (42%), Gaps = 6/143 (4%)
 Frame = +1

Query: 171 SINEWASQTTDGKLPEVTKD--VERTDGALLVNAMFFKPHWDEKFHHKMVDNRGFMVTRS 228
           S+N W    T   +P++     V +    +LV+A+ F   W   F  +      F     
Sbjct: 514 SVNLWVDAVTRATIPDMLXPGAVSQHTLLVLVSALSFWGQWQSNFDERETIPLDF*-NPG 690

Query: 229 YTVG---VTMMHRTGLYNYYDDEKEKLQMVEMPLAHKLSSLIILMPHHVEPLERLEKLLT 285
           +  G   V + HR  L    D  +   +++E+P A+   SL IL+PH    L  LE+ L 
Sbjct: 691 WGHGDGSVHVSHRQLLRE--DGGQGGGKVLEVPYANTRYSLFILLPHSPAGLPGLEQSLD 864

Query: 286 KEQLKAWMGKM-QKKAVAISLPK 307
              L++ +  M   +   + LPK
Sbjct: 865 SVGLQSLLQDMPDPRLTVLLLPK 933
>28968
          Length = 383

 Score = 30.8 bits (68), Expect = 1.1,   Method: Composition-based stats.
 Identities = 12/29 (41%), Positives = 19/29 (65%)
 Frame = +2

Query: 381 FYADHPFIFLVRDNQSGSLLFIGRLVRPK 409
           F  + PF+F++RD +    LFIGR+  P+
Sbjct: 113 FRVNRPFMFVLRDKELRINLFIGRVTDPR 199
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|17933768|ref|NP_525028.1| glyoxylate
reductase/hydroxypyruvate reductase [Mus musculus]
         (328 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

25533                                                                  87   1e-17
12358                                                                  84   8e-17
05955                                                                  57   1e-11
18814                                                                  29   2.6  
03791                                                                  29   2.9  
>25533
          Length = 437

 Score = 86.7 bits (213), Expect = 1e-17,   Method: Compositional matrix adjust.
 Identities = 54/149 (36%), Positives = 78/149 (52%), Gaps = 2/149 (1%)
 Frame = +2

Query: 124 RRLPEAIEEVKNGGWSSWSPLWMCGYGLSQSTVGIVGLGRIGQAIARRLKPFGVQRFLYT 183
           R L  A + +K G W   + +   G  L+  T+ I+GLGRIG+ +A R++ FG+    Y 
Sbjct: 2   RDLARAAQSMKEGRWDRKAFM---GIELNGKTLAIIGLGRIGREVALRMQSFGMTTIGY- 169

Query: 184 GRQP--RPQEAAEFQAEFVPIAQLAAESDFIVVSCSLTPDTMGLCSKDFFQKMKNTAIFI 241
              P      AAEF  E++P+ Q+   +DFI V   L P T  L +   F K K     +
Sbjct: 170 --DPIIGADVAAEFDTEWLPLEQIWQRADFITVHTPLIPATTNLINDAVFAKCKKGIRVV 343

Query: 242 NISRGDVVNQEDLYQALASGQIAAAGLDV 270
           N +RG ++ +  L +AL SGQ   AGLDV
Sbjct: 344 NCARGGIIEEAALLRALESGQCGGAGLDV 430
>12358
          Length = 598

 Score = 84.0 bits (206), Expect = 8e-17,   Method: Compositional matrix adjust.
 Identities = 37/62 (59%), Positives = 47/62 (75%)
 Frame = -2

Query: 245 RGDVVNQEDLYQALASGQIAAAGLDVTTPEPLPPSHPLLTLKNCVILPHIGSATYKTRNT 304
           RG V+N + L  AL +G I  AGLDVT PEPLPP+HPL+ L NCV+ PH+GS T+ +RN+
Sbjct: 549 RGGVINHDHLAVALKTGVIGGAGLDVTEPEPLPPTHPLVHLPNCVVTPHMGSNTWDSRNS 370

Query: 305 MS 306
           MS
Sbjct: 369 MS 364
>05955
          Length = 1009

 Score = 57.0 bits (136), Expect(2) = 1e-11,   Method: Compositional matrix adjust.
 Identities = 34/107 (31%), Positives = 52/107 (48%)
 Frame = -3

Query: 155 TVGIVGLGRIGQAIARRLKPFGVQRFLYTGRQPRPQEAAEFQAEFVPIAQLAAESDFIVV 214
           T+GIVGLGR+G A+A R K FG     Y        E +        + +L  +SD + +
Sbjct: 323 TLGIVGLGRVGTAVAVRAKVFGFNVIFYDPYLADGIEKSLGITRVYTLQELLFQSDCVSL 144

Query: 215 SCSLTPDTMGLCSKDFFQKMKNTAIFINISRGDVVNQEDLYQALASG 261
            C+L      L +    ++M+  A  IN +RG +V++  L  AL  G
Sbjct: 143 HCTLNEHNHHLINDYTIKQMRPGAFLINTARGGLVDEHALAVALKDG 3

 Score = 29.6 bits (65), Expect(2) = 1e-11,   Method: Compositional matrix adjust.
 Identities = 36/138 (26%), Positives = 52/138 (37%), Gaps = 13/138 (9%)
 Frame = -1

Query: 12  TGPLPAEGRAALAQAADCEVE-------------QWNSDDPIPRKDLEQGVVGAHGLLCR 58
            GP+      AL    DC VE                S   I  K L + V    G L  
Sbjct: 787 NGPMHPRPLVALLDGRDCSVEMPILKDVATVAFCDAQSTQEIHEKVLNEAV----GALMW 620

Query: 59  LSDRVDKKLLDAAGANLRVISTLSVGVDHLALDEIKKRGIRVGYTPGVLTDATAELAVSL 118
            +  + K+ LD   + LRVI  +  G D++ +    + GI V   PG   +  A+  + L
Sbjct: 619 HTITLTKEDLDKFKS-LRVIIRIGSGFDNVDVKAAGEMGIAVCNVPGYGVEEVADSTLCL 443

Query: 119 LLTTCRRLPEAIEEVKNG 136
           +L   RR       V+ G
Sbjct: 442 ILNLYRRTYWLANMVREG 389
>18814
          Length = 1135

 Score = 29.3 bits (64), Expect = 2.6,   Method: Compositional matrix adjust.
 Identities = 16/56 (28%), Positives = 25/56 (44%)
 Frame = +3

Query: 123 CRRLPEAIEEVKNGGWSSWSPLWMCGYGLSQSTVGIVGLGRIGQAIARRLKPFGVQ 178
           C  +PE ++  +    S ++P  +C + L      IVG  +   AI      FGVQ
Sbjct: 480 CTHIPEPLDSTETNNASQFNPFTLCSFPLKIGNDTIVGHRKCETAI------FGVQ 629
>03791
          Length = 1679

 Score = 28.9 bits (63), Expect = 2.9,   Method: Compositional matrix adjust.
 Identities = 21/59 (35%), Positives = 29/59 (49%), Gaps = 5/59 (8%)
 Frame = -1

Query: 234  MKNTAIFINISRG---DVVNQE--DLYQALASGQIAAAGLDVTTPEPLPPSHPLLTLKN 287
            M N  +F  I  G    V NQ+   ++ + AS  + +  LD+    PLPPSH LL  K 
Sbjct: 1265 MLNQTVFR*IWDGCKTQVQNQDCSIVFSSFASDPLPSIYLDICIKHPLPPSHTLLLEKK 1089
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31981400|ref|NP_035941.2| phenylalanyl-tRNA
synthetase, beta subunit [Mus musculus]
         (589 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

11378                                                                  88   1e-17
14691                                                                  30   3.7  
>11378
          Length = 1688

 Score = 87.8 bits (216), Expect = 1e-17,   Method: Compositional matrix adjust.
 Identities = 38/59 (64%), Positives = 46/59 (77%)
 Frame = -3

Query: 507 GFEIIHGLLDRIMQLLDVPPGEESGGYMIKASAGSAFFPGRCAEIFVGGQSIGKLGVLH 565
           GFE+IHGLLDR+MQLL++PPG    GY ++AS  + FFPGRCA+I   GQ IG LGVLH
Sbjct: 177 GFEVIHGLLDRVMQLLELPPGGGDTGYCLRASDDATFFPGRCADIMARGQKIGTLGVLH 1
>14691
          Length = 406

 Score = 29.6 bits (65), Expect = 3.7,   Method: Composition-based stats.
 Identities = 18/50 (36%), Positives = 21/50 (42%)
 Frame = -2

Query: 204 DNHLKHYLHIIESKPLYPVIYDSNGVVLSMPPIINGNHSKITVNTRNIFI 253
           D HL HY+H+I                 SMP   N N S I   TR +FI
Sbjct: 180 DYHLNHYIHVIMLNA-------------SMPKSKNSNRSIIVGRTRYLFI 70
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|8393988|ref|NP_058577.1| phosphomannomutase 2 [Mus
musculus]
         (242 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

30728                                                                  86   1e-17
13505                                                                  28   4.7  
>30728
          Length = 457

 Score = 85.9 bits (211), Expect = 1e-17,   Method: Compositional matrix adjust.
 Identities = 38/69 (55%), Positives = 52/69 (75%)
 Frame = -3

Query: 173 QISIDVFPEGWDKRYCLRHLEHAGYKTIYFFGDKTMPGGNDHEIFTDPRTVGYTVTAPED 232
           +ISIDV+P+GWDKR+CL+ ++    +TI+FFGDKT  GGNDHEI+ D  T+G+ VT PED
Sbjct: 455 EISIDVYPKGWDKRFCLQFIKKDNIQTIHFFGDKTDEGGNDHEIYEDAGTIGHKVTNPED 276

Query: 233 TRRICEGLF 241
           T +    +F
Sbjct: 275 TVQQLTDMF 249
>13505
          Length = 460

 Score = 27.7 bits (60), Expect = 4.7,   Method: Compositional matrix adjust.
 Identities = 10/18 (55%), Positives = 14/18 (77%)
 Frame = -3

Query: 102 YIANIKLPKKRGTFIEFR 119
           Y+A+I +P+ R TFI FR
Sbjct: 440 YLADITIPRLRNTFIRFR 387
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|86198335|ref|NP_079815.2| nudix-type motif 2 [Mus
musculus]
         (147 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

31274                                                                  57   1e-17
00810                                                                  30   0.45 
>31274
          Length = 993

 Score = 57.0 bits (136), Expect(3) = 1e-17,   Method: Compositional matrix adjust.
 Identities = 25/50 (50%), Positives = 34/50 (68%)
 Frame = +1

Query: 93  YWLAEVKDYNVEIRLSQEHQAYRWLGLEEACQLAQFKEMKATLQEGHQFL 142
           +WL+EVKD N  + LS EH  Y+W GLEEAC+L  F++M   L+E   F+
Sbjct: 169 FWLSEVKDPNCPVILSYEHTEYKWAGLEEACKLLAFEDMIKALREADTFI 318

 Score = 33.9 bits (76), Expect(3) = 1e-17,   Method: Compositional matrix adjust.
 Identities = 14/28 (50%), Positives = 20/28 (71%)
 Frame = +2

Query: 66  EASQLTIIEGFRRELNYVARQKPKTVIY 93
           E  QL I++GF+ EL+Y A  KPK V++
Sbjct: 89  EKEQLCILDGFQTELHYTAFSKPKRVVF 172

 Score = 33.5 bits (75), Expect(3) = 1e-17,   Method: Compositional matrix adjust.
 Identities = 12/15 (80%), Positives = 13/15 (86%)
 Frame = +3

Query: 37 HWTPPKGHVDPGEND 51
          HW  PKGHVDPGE+D
Sbjct: 3  HWGTPKGHVDPGESD 47
>00810
          Length = 1431

 Score = 29.6 bits (65), Expect = 0.45,   Method: Compositional matrix adjust.
 Identities = 13/49 (26%), Positives = 23/49 (46%)
 Frame = +1

Query: 1   MALRACGLIIFRRHLIPKMDNSTIEFLLLQASDGIHHWTPPKGHVDPGE 49
            +L AC      +H +     +  ++  +Q ++  H +TPPK H  PG 
Sbjct: 295 TSLHAC------KHYVLSFYTTQTKYSFVQRNNPTHPFTPPKQHTKPGN 423
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|9789999|ref|NP_062806.1| G kinase anchoring protein 1
[Mus musculus]
         (366 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

16966                                                                  87   1e-17
04732                                                                  29   2.4  
09899                                                                  29   2.9  
>16966
          Length = 1953

 Score = 87.0 bits (214), Expect = 1e-17,   Method: Compositional matrix adjust.
 Identities = 83/258 (32%), Positives = 131/258 (50%), Gaps = 14/258 (5%)
 Frame = -1

Query: 109  ENWQEWRQKDEQLTSEMFEADLEKALLLSKLEYEEHKQDYENAE-------TASTQTKGI 161
            E+W EW+++D ++T +M++ DL++ALL SKLE E  KQ     E        + T + G 
Sbjct: 1623 EDWDEWQRRDVEVTEDMYQHDLQQALLDSKLEAEHQKQARREMEAEMLASGVSVTASAGQ 1444

Query: 162  NKKDKRKNHQG------KDKPV-TVSLKDFQCEDHISKKAEESNSAQTLSHDGGFFNRLE 214
             KK K+   Q       K  PV TV   D + ED                 D  +F  + 
Sbjct: 1443 KKKKKKDKPQAMSLDQFKQMPVETVPGSDDENEDPAPPPVH--TRVPVACQDKQYFESVA 1270

Query: 215  DDVHKILIREKRREQLTEHNGTDNSPAPEHNQEVGLKDGRIERLKLELERKDAEIQKLKA 274
             +  KIL +E+ +EQ  +    +++   ++  ++  K   I++LK +LE + AE+     
Sbjct: 1269 TESSKILQKERIQEQYQKAYAHESAMQSKYQDDIEKKVKEIKKLKTQLEEQGAEL----- 1105

Query: 275  VITQWEAKYKEVKARNGQLLKMLQEGEMKDKAEILLQVDESQSIKNELTVQVSSLHAALE 334
                     K VK RN +L K+L +GEMK+K  IL+QV+E  S K +LT Q++++ A LE
Sbjct: 1104 ---------KSVKGRNARLCKILADGEMKEKTSILMQVEELTSDKEDLTAQLAAMTAELE 952

Query: 335  QERSKVKVLQAELAKYQG 352
            +ERSK    + E  K +G
Sbjct: 951  KERSKNHAFKLENDKLKG 898

 Score = 45.8 bits (107), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 19/38 (50%), Positives = 30/38 (78%)
 Frame = -2

Query: 109 ENWQEWRQKDEQLTSEMFEADLEKALLLSKLEYEEHKQ 146
           E+W EW+++D ++T +M++ DL++ALL SKLE E  KQ
Sbjct: 383 EDWDEWQRRDVEVTEDMYQHDLQQALLDSKLEAEHQKQ 270
>04732
          Length = 963

 Score = 29.3 bits (64), Expect = 2.4,   Method: Compositional matrix adjust.
 Identities = 18/40 (45%), Positives = 23/40 (57%), Gaps = 4/40 (10%)
 Frame = -2

Query: 331 AALEQERSKVKV----LQAELAKYQGGRKGKRNFEPDHCR 366
           A  E ERS+ +V    LQA +A  QG RKG+ N + D  R
Sbjct: 860 ARFEMERSQWEVERAELQARIAFLQGERKGQENLKQDLVR 741
>09899
          Length = 1401

 Score = 29.3 bits (64), Expect = 2.9,   Method: Compositional matrix adjust.
 Identities = 18/40 (45%), Positives = 23/40 (57%), Gaps = 4/40 (10%)
 Frame = +1

Query: 331 AALEQERSKVKV----LQAELAKYQGGRKGKRNFEPDHCR 366
           A  E ERS+ +V    LQA +A  QG RKG+ N + D  R
Sbjct: 103 ARFEMERSQWEVERAELQARIAFLQGERKGQENLKQDLVR 222
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|116063560|ref|NP_058062.2| contactin associated
protein 1 [Mus musculus]
         (1385 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

29854                                                                  88   2e-17
18680                                                                  49   1e-05
13401                                                                  35   0.21 
12576                                                                  34   0.42 
18458                                                                  33   1.1  
03304                                                                  32   2.5  
03449                                                                  31   4.2  
32228                                                                  30   4.9  
>29854
          Length = 417

 Score = 88.2 bits (217), Expect = 2e-17,   Method: Composition-based stats.
 Identities = 49/133 (36%), Positives = 67/133 (50%), Gaps = 3/133 (2%)
 Frame = -1

Query: 555 RCYQSWDDFICYCELTGYKGVTCHEPLYKESCEAYRLSGKYSGN--YTIDPDGSGPLKPF 612
           +C QSW+ F C C+ TGYKG  CH   +  SCE ++      G     IDPDGSGPL PF
Sbjct: 417 KCTQSWNTFDCDCQNTGYKGEMCHISAHHISCEMHKQYSNIEGAELAVIDPDGSGPLPPF 238

Query: 613 VVYCDIRENRA-WTVVRHDRLWTTRVTGSSMDRPFLGAIQYWNASWEEVSALANASQHCE 671
            V CD   +R   T + HD      V G S    ++  I Y   +   +  +   +  C 
Sbjct: 237 EVTCDRDADRTIMTSIGHDSQDYILVNGFSEPGSYVRKIHYVTDNMLALEDIIERADTCR 58

Query: 672 QWIEFSCYNSRLL 684
           Q+I++ C NS+LL
Sbjct: 57  QYIDYRCNNSKLL 19
>18680
          Length = 451

 Score = 48.9 bits (115), Expect = 1e-05,   Method: Composition-based stats.
 Identities = 21/60 (35%), Positives = 31/60 (51%)
 Frame = -3

Query: 968  PCFHGGRCVERYSYYTCDCDLTAFDGPYCNHDIGGFFETGTWMRYNLQSALRSAAREFSH 1027
            PCF+GG C E YS YTCDC  T + G  C  ++G   +    ++Y        +A +F +
Sbjct: 434  PCFNGGTCREGYSRYTCDCSYTPWRGWNCGREVGVNLKQNYMIQYEFTEQQGLSATDFQY 255

 Score = 31.6 bits (70), Expect = 2.5,   Method: Composition-based stats.
 Identities = 10/34 (29%), Positives = 18/34 (52%)
 Frame = -3

Query: 544 RCSPNMCEHDGRCYQSWDDFICYCELTGYKGVTC 577
           +C+ N C + G C + +  + C C  T ++G  C
Sbjct: 449 KCASNPCFNGGTCREGYSRYTCDCSYTPWRGWNC 348
>13401
          Length = 497

 Score = 35.0 bits (79), Expect = 0.21,   Method: Compositional matrix adjust.
 Identities = 32/107 (29%), Positives = 42/107 (39%), Gaps = 15/107 (14%)
 Frame = -3

Query: 486 GGCPKPASRWGCHSNQTAFHG--CMELLK-------------VDGQLVNLTLVEFRKLGY 530
           G C    S + CH + T F G  C E +              VDG  +          GY
Sbjct: 306 GRCQDTVSGFTCHCSGTGFQGNRCEENVDDCVNHRCENGAPCVDG--IRQYFCNCTGTGY 133

Query: 531 FAEVLFDTCGITDRCSPNMCEHDGRCYQSWDDFICYCELTGYKGVTC 577
             E        TD C+ + C++ G C Q  + F C C  TGY+G TC
Sbjct: 132 EGEFCQTD---TDECASSPCKNGGNCSQGNNKFQCTCTDTGYRGDTC 1

 Score = 32.3 bits (72), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 14/33 (42%), Positives = 19/33 (57%)
 Frame = -3

Query: 968  PCFHGGRCVERYSYYTCDCDLTAFDGPYCNHDI 1000
            PCF+ GRC +  S +TC C  T F G  C  ++
Sbjct: 321  PCFNAGRCQDTVSGFTCHCSGTGFQGNRCEENV 223
>12576
          Length = 1682

 Score = 33.9 bits (76), Expect = 0.42,   Method: Composition-based stats.
 Identities = 14/31 (45%), Positives = 19/31 (61%)
 Frame = -1

Query: 547  PNMCEHDGRCYQSWDDFICYCELTGYKGVTC 577
            PN C + GRC ++   F C C + GY G+TC
Sbjct: 1427 PNPCRNGGRCNRNGASFSCVC-VGGYNGLTC 1338

 Score = 32.0 bits (71), Expect = 1.6,   Method: Composition-based stats.
 Identities = 20/58 (34%), Positives = 26/58 (44%), Gaps = 8/58 (13%)
 Frame = -1

Query: 538  TC-GITDRCSPNMCEHDGRCYQSWD----DFICYCELTGYKGVTCHE---PLYKESCE 587
            TC G+ D CS N C + GRC          F C C + GY G  C +   P   + C+
Sbjct: 1091 TCTGLNDPCSSNPCRNGGRCSSVAQGGALTFSCXC-INGYTGXDCSQTADPCSSKPCK 921

 Score = 31.2 bits (69), Expect = 3.3,   Method: Composition-based stats.
 Identities = 19/58 (32%), Positives = 27/58 (46%), Gaps = 8/58 (13%)
 Frame = -1

Query: 537  DTC-GITDRCSPNMCEHDGRCYQSWD----DFICYCELTGYKGVTC---HEPLYKESC 586
            +TC  + D C PN C++ G C  +       F C+C   GY G TC   ++P     C
Sbjct: 1220 NTCQTLADPCKPNPCKNGGLCSTTVVGGALTFKCFCS-AGYDGKTCTGLNDPCSSNPC 1050

 Score = 30.8 bits (68), Expect = 4.0,   Method: Composition-based stats.
 Identities = 18/46 (39%), Positives = 24/46 (52%), Gaps = 5/46 (10%)
 Frame = -1

Query: 538  TCG-ITDRCSPNMCEHDGRCYQ--SWDDFI--CYCELTGYKGVTCH 578
            TC  ++D C+PN C + G C    S    +  CYC   GY+G TC 
Sbjct: 1343 TCASLSDPCNPNPCRNGGVCSTEVSGGKLVSKCYCA-NGYEGNTCQ 1209
>18458
          Length = 1885

 Score = 32.7 bits (73), Expect = 1.1,   Method: Composition-based stats.
 Identities = 16/39 (41%), Positives = 22/39 (56%)
 Frame = +1

Query: 199  VFAFSFKTEEKDGLLLHTEGSQGDYVTLELQGAHLLLHM 237
            VF+   +T+  D   LHT+ SQ  YV + LQ  H  LH+
Sbjct: 1633 VFSLILQTDCNDNRKLHTQYSQSGYVYINLQRGHQSLHI 1749
>03304
          Length = 1471

 Score = 31.6 bits (70), Expect = 2.5,   Method: Composition-based stats.
 Identities = 17/56 (30%), Positives = 28/56 (50%)
 Frame = +3

Query: 901 PMPLQTYIWLVYDQPLYVGSAELKRRPFVGCLRAMRLNGVTLNLEGRANASEGTFP 956
           PMP+++  WL    P+Y+ +A  +R   +  L   R N V LN   + + +   FP
Sbjct: 264 PMPVKSATWL*IPMPVYITAAASQR*AQLVDLSTARXNRVPLNFTHQHSQTFHIFP 431
>03449
          Length = 1720

 Score = 30.8 bits (68), Expect = 4.2,   Method: Compositional matrix adjust.
 Identities = 14/31 (45%), Positives = 18/31 (58%), Gaps = 1/31 (3%)
 Frame = -1

Query: 724  CVDPALHCNCDADQPQWRTDKGL-LTFVDHL 753
            C+ PA  C+C    P+W  D GL  +FV HL
Sbjct: 1120 CIPPAGRCSCTTPGPKWPLDPGLSSSFVFHL 1028
>32228
          Length = 1295

 Score = 30.4 bits (67), Expect = 4.9,   Method: Compositional matrix adjust.
 Identities = 14/32 (43%), Positives = 19/32 (59%), Gaps = 1/32 (3%)
 Frame = -3

Query: 956  PNCTGHCTHPRF-PCFHGGRCVERYSYYTCDC 986
            P C    TH +  PC  GG+C E ++ +TCDC
Sbjct: 1077 PGCPQKHTHCQSSPCTLGGKCKEGWNTFTCDC 982
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|165932375|ref|NP_080090.2| SERPINE1 mRNA binding
protein 1 isoform 1 [Mus musculus]
         (407 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

03497                                                                  86   2e-17
23925                                                                  55   4e-08
23248                                                                  55   6e-08
>03497
          Length = 1094

 Score = 86.3 bits (212), Expect = 2e-17,   Method: Compositional matrix adjust.
 Identities = 56/137 (40%), Positives = 73/137 (53%), Gaps = 2/137 (1%)
 Frame = +2

Query: 192 EFDRHSGSDRSSFSHYSGLKHEDKRGGSGSHNWGTVKDELTESPKYIQKQISYNCSDLDQ 251
           EFDRHSG+DRS      G+K  DKR GSG+HNWG+ +D++ +  +        N +D   
Sbjct: 2   EFDRHSGTDRS------GVKPTDKRDGSGAHNWGSYRDDVEDQGQ------GTNPADT-- 139

Query: 252 SNVTEETPEGEEHPVAD-TXXXXXXXXXXXXXGPKEMTLDEWKAIQNKDRAKVEFNIRKP 310
               E  P   + P A+ T              PKEMTLDEWKA Q++ R K ++NIR+ 
Sbjct: 140 --SGEWAPPAADQPEAEQTEGGETAAPPKEDEEPKEMTLDEWKAQQDQRRMKAQYNIRRA 313

Query: 311 NEGAD-GQWKKGFVLHK 326
            EG D  QWKKG    K
Sbjct: 314 GEGVDSNQWKKGVAYKK 364
>23925
          Length = 736

 Score = 55.5 bits (132), Expect = 4e-08,   Method: Compositional matrix adjust.
 Identities = 26/44 (59%), Positives = 31/44 (70%), Gaps = 1/44 (2%)
 Frame = +3

Query: 284 PKEMTLDEWKAIQNKDRAKVEFNIRKPNEGAD-GQWKKGFVLHK 326
           PKEMTLDEWKA Q++ R K ++NIR+  EG D  QWKKG    K
Sbjct: 99  PKEMTLDEWKAQQDQRRMKAQYNIRRAGEGVDSNQWKKGVAYKK 230
>23248
          Length = 1524

 Score = 54.7 bits (130), Expect = 6e-08,   Method: Compositional matrix adjust.
 Identities = 26/44 (59%), Positives = 31/44 (70%), Gaps = 1/44 (2%)
 Frame = +2

Query: 284 PKEMTLDEWKAIQNKDRAKVEFNIRKPNEGAD-GQWKKGFVLHK 326
           PKEMTLDEWKA++++ R K  +NIRK  EG D  QWKKG    K
Sbjct: 80  PKEMTLDEWKALEDQRRLKASYNIRKAGEGVDNNQWKKGVAYKK 211
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6679805|ref|NP_032046.1| FK506 binding protein 2,
13kDa [Mus musculus]
         (140 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

00162                                                                  84   2e-17
00011                                                                  62   2e-16
37162                                                                  44   6e-15
00888                                                                  44   2e-05
19167                                                                  25   8.3  
>00162
          Length = 2322

 Score = 83.6 bits (205), Expect = 2e-17,   Method: Compositional matrix adjust.
 Identities = 47/100 (47%), Positives = 67/100 (67%), Gaps = 1/100 (1%)
 Frame = +2

Query: 36   RVDHCPIKSRKGDVLHMHYTGKL-EDGTEFDSSLPQNQPFVFSLGTGQVIKGWDQGLLGM 94
            +V H P +++ G ++ ++Y+G L ++   FDS L + +PF F LG G+VIKGWD GL+GM
Sbjct: 1925 KVGHGP-EAKPGHLVSVYYSGTLAKNNKRFDSCL-KGKPFRFKLGRGEVIKGWDNGLIGM 2098

Query: 95   CEGEKRKLVIPSELGYGERGAPPKIPGGATLVFEVELLKI 134
              G KRK+ +PS  GYG     P IP G+TLVF+VEL  +
Sbjct: 2099 RVGGKRKITVPSSQGYGNSRQGP-IPPGSTLVFDVELKAV 2215
>00011
          Length = 1711

 Score = 62.0 bits (149), Expect(2) = 2e-16,   Method: Compositional matrix adjust.
 Identities = 29/62 (46%), Positives = 37/62 (59%)
 Frame = +1

Query: 72  QPFVFSLGTGQVIKGWDQGLLGMCEGEKRKLVIPSELGYGERGAPPKIPGGATLVFEVEL 131
           Q   F +GTGQVIK WD+G++ M  GE+  L    +  YG  G    IP  ATL+F+VEL
Sbjct: 235 QAICFKIGTGQVIKAWDEGVMKMSVGERATLTASPDYAYGRNGIGDIIPPNATLIFDVEL 414

Query: 132 LK 133
           L 
Sbjct: 415 LS 420

 Score = 38.9 bits (89), Expect(2) = 2e-16,   Method: Compositional matrix adjust.
 Identities = 16/34 (47%), Positives = 23/34 (67%)
 Frame = +2

Query: 45  RKGDVLHMHYTGKLEDGTEFDSSLPQNQPFVFSL 78
           + GD + +HYTG L +G +FDSS  + +PFV  L
Sbjct: 155 KAGDSVQVHYTGTLTNGKKFDSSRDRGKPFVLKL 256
>37162
          Length = 601

 Score = 43.5 bits (101), Expect(3) = 6e-15,   Method: Compositional matrix adjust.
 Identities = 23/47 (48%), Positives = 29/47 (61%), Gaps = 1/47 (2%)
 Frame = -2

Query: 45  RKGDVLHMHYTGKLEDGTEFDSSLPQ-NQPFVFSLGTGQVIKGWDQG 90
           R GD + +HYTG LE G  FDSS+    +P  F LG  +VI GW+ G
Sbjct: 588 RDGDGVAVHYTGYLETGAVFDSSVQAGREPLEFLLGERKVIPGWEMG 448

 Score = 40.8 bits (94), Expect(3) = 6e-15,   Method: Compositional matrix adjust.
 Identities = 17/25 (68%), Positives = 19/25 (76%)
 Frame = -3

Query: 93  GMCEGEKRKLVIPSELGYGERGAPP 117
           GMC GEKRKL+IP  L YG+ G PP
Sbjct: 440 GMCVGEKRKLIIPPHLAYGQTGYPP 366

 Score = 31.2 bits (69), Expect(3) = 6e-15,   Method: Compositional matrix adjust.
 Identities = 11/24 (45%), Positives = 17/24 (70%)
 Frame = -1

Query: 114 GAPPKIPGGATLVFEVELLKIERR 137
             PP IP  ATL FE EL++++++
Sbjct: 376 ATPPAIPEDATLTFETELIRLDKK 305
>00888
          Length = 970

 Score = 44.3 bits (103), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 21/55 (38%), Positives = 32/55 (58%), Gaps = 1/55 (1%)
 Frame = -3

Query: 83  VIKGWDQGLLGMCEGEKRKLVIPSELGYGERGAPP-KIPGGATLVFEVELLKIER 136
           +I G +   L M +GE+ +L + S+  YGE G     IP  ATLV+ VE++  E+
Sbjct: 950 IIAGIELATLKMKKGERDQLTVASKYAYGEEGCXRFNIPSNATLVYNVEMVNFEK 786
>19167
          Length = 608

 Score = 25.4 bits (54), Expect = 8.3,   Method: Compositional matrix adjust.
 Identities = 13/40 (32%), Positives = 22/40 (55%)
 Frame = -1

Query: 22  GAEGKRKLQIGVKKRVDHCPIKSRKGDVLHMHYTGKLEDG 61
            A+G  ++ I V ++V    I+  +GD + +  T  LEDG
Sbjct: 512 AADGNIRIVIAVNRQVPGPLIEVCEGDTVEVRVTNMLEDG 393
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6680946|ref|NP_031731.1| cold inducible RNA binding
protein [Mus musculus]
         (172 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

16427                                                                  85   2e-17
00302                                                                  81   3e-16
19868                                                                  71   2e-13
00817                                                                  70   6e-13
16016                                                                  69   1e-12
32386                                                                  67   4e-12
02415                                                                  66   6e-12
03000                                                                  66   7e-12
33516                                                                  63   6e-11
02347                                                                  62   8e-11
31618                                                                  62   2e-10
24983                                                                  60   4e-10
20169                                                                  59   7e-10
11019                                                                  59   1e-09
23322                                                                  56   6e-09
02140                                                                  56   7e-09
26197                                                                  56   9e-09
03406                                                                  55   1e-08
39789                                                                  54   3e-08
30672                                                                  53   5e-08
12506                                                                  53   6e-08
01937                                                                  53   6e-08
04988                                                                  53   7e-08
03059                                                                  53   7e-08
10194                                                                  53   7e-08
23720                                                                  53   7e-08
31310                                                                  52   1e-07
01278                                                                  52   1e-07
00029                                                                  51   2e-07
08958                                                                  50   4e-07
13822                                                                  50   4e-07
02809                                                                  50   6e-07
20488                                                                  47   4e-06
03744                                                                  47   4e-06
28455                                                                  47   4e-06
05273                                                                  47   5e-06
14637                                                                  46   7e-06
28605                                                                  45   1e-05
11108                                                                  45   1e-05
14258                                                                  45   2e-05
17775                                                                  45   2e-05
29364                                                                  44   3e-05
12350                                                                  44   3e-05
21527                                                                  44   3e-05
02502                                                                  44   4e-05
09968                                                                  42   1e-04
02343                                                                  42   2e-04
11579                                                                  41   3e-04
03200                                                                  41   3e-04
11126                                                                  40   4e-04
00556                                                                  39   0.001
25691                                                                  39   0.001
25950                                                                  39   0.001
28652                                                                  39   0.001
23655                                                                  38   0.002
33504                                                                  37   0.003
19556                                                                  37   0.005
28372                                                                  35   0.019
25431                                                                  32   0.12 
35379                                                                  32   0.13 
25632                                                                  32   0.13 
13457                                                                  32   0.14 
38650                                                                  30   0.66 
02064                                                                  29   0.76 
35767                                                                  29   0.91 
19980                                                                  29   1.1  
12096                                                                  29   1.3  
15752                                                                  28   2.4  
30934                                                                  27   5.0  
09736                                                                  27   5.0  
>16427
          Length = 1313

 Score = 84.7 bits (208), Expect = 2e-17,   Method: Compositional matrix adjust.
 Identities = 39/78 (50%), Positives = 61/78 (78%)
 Frame = +1

Query: 5   EGKLFVGGLSFDTNEQALEQVFSKYGQISEVVVVKDRETQRSRGFGFVTFENIDDAKDAM 64
            GKLFVGGL+ + +E+ LE+ FSK+G+I+E +V++D+  Q SRGFGFVT+EN  DA++A+
Sbjct: 133 PGKLFVGGLAEEIDEKVLEREFSKFGRITESMVIRDKVRQVSRGFGFVTYENPMDAEEAV 312

Query: 65  MAMNGKSVDGRQIRVDQA 82
             M+GK + G+++ V+ A
Sbjct: 313 KHMDGKEILGKKLHVEDA 366
>00302
          Length = 927

 Score = 80.9 bits (198), Expect = 3e-16,   Method: Compositional matrix adjust.
 Identities = 40/73 (54%), Positives = 51/73 (69%)
 Frame = -1

Query: 8   LFVGGLSFDTNEQALEQVFSKYGQISEVVVVKDRETQRSRGFGFVTFENIDDAKDAMMAM 67
           L + GLS  T E+ L +VF +YG ISEV VV DR+T RSRGF FV F++ +DA +A    
Sbjct: 459 LGIFGLSLYTQERGLREVFGRYGHISEVQVVYDRQTGRSRGFAFVYFKSSEDAHEAKDRC 280

Query: 68  NGKSVDGRQIRVD 80
           NG  +DGR+IRVD
Sbjct: 279 NGIEIDGRKIRVD 241
>19868
          Length = 434

 Score = 70.9 bits (172), Expect = 2e-13,   Method: Compositional matrix adjust.
 Identities = 33/71 (46%), Positives = 53/71 (74%)
 Frame = +2

Query: 7  KLFVGGLSFDTNEQALEQVFSKYGQISEVVVVKDRETQRSRGFGFVTFENIDDAKDAMMA 66
          K+FVGGLS+ T+ ++L   F+K+G+I+EV+V+KD  T+RSRGFGF+TF +   + D ++A
Sbjct: 2  KMFVGGLSWQTSPESLRDYFNKFGEITEVMVMKDPTTRRSRGFGFITFGD-PASVDKVLA 178

Query: 67 MNGKSVDGRQI 77
               +DG++I
Sbjct: 179QATHELDGKKI 211

 Score = 49.7 bits (117), Expect = 6e-07,   Method: Compositional matrix adjust.
 Identities = 22/53 (41%), Positives = 35/53 (66%)
 Frame = +2

Query: 1   MASDEGKLFVGGLSFDTNEQALEQVFSKYGQISEVVVVKDRETQRSRGFGFVT 53
           M +   K+FVGGLS  T  + ++  F ++G I + +++ D++T R RGFGFVT
Sbjct: 251 MVTRTKKIFVGGLSAPTTLEDVKNYFEQFGPIEDAMLMFDKQTNRHRGFGFVT 409
>00817
          Length = 2606

 Score = 69.7 bits (169), Expect = 6e-13,   Method: Compositional matrix adjust.
 Identities = 33/74 (44%), Positives = 50/74 (67%), Gaps = 4/74 (5%)
 Frame = -2

Query: 7    KLFVGGLSFDTNEQALEQVFSKYGQISEVVVVKDRETQRSRGFGFVTF---ENIDDA-KD 62
            K+F+GG+  DT+E +L   F KYG I E +VVKD  T+RSR F F+TF   EN+D+  KD
Sbjct: 2548 KVFIGGMHPDTDESSLRSYFEKYGDIRECIVVKDPATKRSRCFSFITFGNAENVDEVQKD 2369

Query: 63   AMMAMNGKSVDGRQ 76
                ++G++V+ ++
Sbjct: 2368 RPHTIDGRTVETKR 2327
>16016
          Length = 1364

 Score = 68.9 bits (167), Expect = 1e-12,   Method: Compositional matrix adjust.
 Identities = 33/74 (44%), Positives = 50/74 (67%), Gaps = 4/74 (5%)
 Frame = -2

Query: 7    KLFVGGLSFDTNEQALEQVFSKYGQISEVVVVKDRETQRSRGFGFVTF---ENIDDA-KD 62
            K+F+GG+  DT+E +L   F KYG I E +VVKD  T+RSR F F+TF   EN+D+  KD
Sbjct: 1306 KVFIGGMHPDTDESSLRSYFEKYGDIRECIVVKDPATKRSRCFSFITFGNAENVDEVQKD 1127

Query: 63   AMMAMNGKSVDGRQ 76
                ++G++V+ ++
Sbjct: 1126 RPHTIDGRTVETKR 1085

 Score = 30.8 bits (68), Expect(2) = 2e-04,   Method: Compositional matrix adjust.
 Identities = 15/53 (28%), Positives = 29/53 (54%)
 Frame = -1

Query: 35  VVVVKDRETQRSRGFGFVTFENIDDAKDAMMAMNGKSVDGRQIRVDQAGKSSD 87
           + ++KD+ T + RGF FV+F++ D   D         ++GR +   +A + S+
Sbjct: 965 INMIKDKSTGKFRGFCFVSFDDCDTV-DKHAIHKCFKINGRHVEAKKASQQSE 810

 Score = 29.6 bits (65), Expect(2) = 2e-04,   Method: Compositional matrix adjust.
 Identities = 14/30 (46%), Positives = 21/30 (70%)
 Frame = -2

Query: 7    KLFVGGLSFDTNEQALEQVFSKYGQISEVV 36
            K+FVGGL  DT E+ L + F+  G+I+E+ 
Sbjct: 1042 KMFVGGLKDDTTEEMLRKEFT--GKITELT 959
>32386
          Length = 674

 Score = 67.0 bits (162), Expect = 4e-12,   Method: Compositional matrix adjust.
 Identities = 32/79 (40%), Positives = 53/79 (67%), Gaps = 3/79 (3%)
 Frame = +1

Query: 7   KLFVGGLSFDTNEQALEQVFSKYGQISEVVVVKDRETQRSRGFGFVTF---ENIDDAKDA 63
           KLF+GGLS++T+E +L   F  +G+I + +V++D  ++RSRGFGF+T+   E+ID A+  
Sbjct: 304 KLFIGGLSYETDEDSLRSHFETWGEIVDCIVMRDSNSKRSRGFGFITYKDAESIDQAQ-- 477

Query: 64  MMAMNGKSVDGRQIRVDQA 82
             A     +DGR++   +A
Sbjct: 478 --ANRPHKIDGREVDTKRA 528
>02415
          Length = 2763

 Score = 66.2 bits (160), Expect = 6e-12,   Method: Compositional matrix adjust.
 Identities = 33/76 (43%), Positives = 47/76 (61%)
 Frame = -1

Query: 7    KLFVGGLSFDTNEQALEQVFSKYGQISEVVVVKDRETQRSRGFGFVTFENIDDAKDAMMA 66
            K+FVGGL + T + +L + F K+G I E VV+ DR+T +SRG+GFVT  +   A  A   
Sbjct: 1923 KIFVGGLPYHTTDHSLREYFDKFGDIDEAVVITDRQTGKSRGYGFVTMADRTGADRACKD 1744

Query: 67   MNGKSVDGRQIRVDQA 82
             N   +DGR+  V+ A
Sbjct: 1743 PN-PIIDGRKANVNLA 1699
>03000
          Length = 778

 Score = 66.2 bits (160), Expect = 7e-12,   Method: Compositional matrix adjust.
 Identities = 29/76 (38%), Positives = 52/76 (68%)
 Frame = +3

Query: 7   KLFVGGLSFDTNEQALEQVFSKYGQISEVVVVKDRETQRSRGFGFVTFENIDDAKDAMMA 66
           KLF+GGLS++T+E +L   F  +G+I + +V++D  ++RSRGFGF+T+++  ++ D   A
Sbjct: 90  KLFIGGLSYETDEDSLRSHFETWGEIVDCIVMRDSNSKRSRGFGFITYKDA-ESIDQAQA 266

Query: 67  MNGKSVDGRQIRVDQA 82
                +DGR++   +A
Sbjct: 267 NRPHKIDGREVDTKRA 314

 Score = 55.8 bits (133), Expect = 8e-09,   Method: Compositional matrix adjust.
 Identities = 29/81 (35%), Positives = 51/81 (62%)
 Frame = +3

Query: 7   KLFVGGLSFDTNEQALEQVFSKYGQISEVVVVKDRETQRSRGFGFVTFENIDDAKDAMMA 66
           K+FVGG+  DT E  +   F+++G+I+ V +++D+ T ++RGF FVTF + D    A++ 
Sbjct: 363 KMFVGGVKEDTTEDMIRDTFNEFGEITGVDLIQDKGTGKNRGFCFVTFGDHDSVDKAVLK 542

Query: 67  MNGKSVDGRQIRVDQAGKSSD 87
                ++GRQ+ V +A   +D
Sbjct: 543 KR-HDLNGRQVEVKKAQSKND 602
>33516
          Length = 449

 Score = 63.2 bits (152), Expect = 6e-11,   Method: Compositional matrix adjust.
 Identities = 25/53 (47%), Positives = 46/53 (86%)
 Frame = +1

Query: 4   DEGKLFVGGLSFDTNEQALEQVFSKYGQISEVVVVKDRETQRSRGFGFVTFEN 56
           + GK+FVGGLS+DT++ +L+  FS++G+I++ +V+ +++T +SRGFGFV+F++
Sbjct: 148 EPGKIFVGGLSWDTDQDSLQGYFSQFGEITDCIVMMNQQTGKSRGFGFVSFKD 306
>02347
          Length = 928

 Score = 62.4 bits (150), Expect = 8e-11,   Method: Compositional matrix adjust.
 Identities = 31/81 (38%), Positives = 50/81 (61%)
 Frame = -3

Query: 2   ASDEGKLFVGGLSFDTNEQALEQVFSKYGQISEVVVVKDRETQRSRGFGFVTFENIDDAK 61
           +S EGK++VG L  D +E+ +E+ F+ YG +  V V ++       GF FV FE+  DA 
Sbjct: 758 SSVEGKIYVGDLPPDASEKEVERAFNYYGHLRNVWVARN-----PPGFAFVEFEDTRDAD 594

Query: 62  DAMMAMNGKSVDGRQIRVDQA 82
           DA+ A++G  V G ++RV+ +
Sbjct: 593 DAVRALDGTVVCGNRVRVEHS 531
>31618
          Length = 716

 Score = 61.6 bits (148), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 34/75 (45%), Positives = 46/75 (61%), Gaps = 5/75 (6%)
 Frame = +1

Query: 7   KLFVGGLSFDTNEQALEQVFSKYGQISEVVVVKDRETQRSRGFGFVTFENIDDAKDAMMA 66
           KLFVGGLS++T E+ L   F KYG+I  + V  D +T RSRGF F+ F N  +A D + A
Sbjct: 295 KLFVGGLSWETTEKELRDHFGKYGEIESINVKTDPQTGRSRGFAFIVFTN-TEAIDQVSA 471

Query: 67  -----MNGKSVDGRQ 76
                +N K VD ++
Sbjct: 472 AEEHIINSKKVDPKK 516

 Score = 29.3 bits (64), Expect(2) = 0.093,   Method: Compositional matrix adjust.
 Identities = 11/26 (42%), Positives = 21/26 (80%)
 Frame = +3

Query: 6   GKLFVGGLSFDTNEQALEQVFSKYGQ 31
           GK+FVGGL+ + +++ ++  FS++GQ
Sbjct: 534 GKIFVGGLTTEISDEEIKTYFSQFGQ 611

 Score = 21.9 bits (45), Expect(2) = 0.093,   Method: Compositional matrix adjust.
 Identities = 9/25 (36%), Positives = 16/25 (64%)
 Frame = +1

Query: 32  ISEVVVVKDRETQRSRGFGFVTFEN 56
           I EV +  D++    +GF F+TF++
Sbjct: 613 IVEVEMPFDKQKSHRKGFXFITFDS 687
>24983
          Length = 433

 Score = 60.5 bits (145), Expect = 4e-10,   Method: Compositional matrix adjust.
 Identities = 30/74 (40%), Positives = 44/74 (59%)
 Frame = -2

Query: 9   FVGGLSFDTNEQALEQVFSKYGQISEVVVVKDRETQRSRGFGFVTFENIDDAKDAMMAMN 68
            +GGL + T + +L + F K+G I E VV+ DR+T +SRG+GFVT  +   A  A    N
Sbjct: 306 LLGGLPYHTTDHSLREYFDKFGDIDEAVVITDRQTGKSRGYGFVTMADRTGADRACKDPN 127

Query: 69  GKSVDGRQIRVDQA 82
              +DGR+  V+ A
Sbjct: 126 -PIIDGRKANVNLA 88
>20169
          Length = 1364

 Score = 59.3 bits (142), Expect = 7e-10,   Method: Compositional matrix adjust.
 Identities = 30/74 (40%), Positives = 45/74 (60%)
 Frame = -1

Query: 7    KLFVGGLSFDTNEQALEQVFSKYGQISEVVVVKDRETQRSRGFGFVTFENIDDAKDAMMA 66
            K++VG L     +Q LE  F+KYG +  V V +     R  GF FV FE+  DA+DA+ A
Sbjct: 1067 KVYVGELGHGCAKQELEDKFAKYGPLKNVWVAR-----RPAGFAFVEFEDNRDAEDAVQA 903

Query: 67   MNGKSVDGRQIRVD 80
            ++G  ++GR+ RV+
Sbjct: 902  LDGARINGRRARVE 861
>11019
          Length = 552

 Score = 58.9 bits (141), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 26/68 (38%), Positives = 44/68 (64%)
 Frame = -1

Query: 10  VGGLSFDTNEQALEQVFSKYGQISEVVVVKDRETQRSRGFGFVTFENIDDAKDAMMAMNG 69
           +GGLS+ T  + L   F K+G+I E +V+KD  ++RSRGFGFVT+++  +  D ++A   
Sbjct: 552 IGGLSWQTTTETLRSYFEKFGEIKESMVMKDPTSKRSRGFGFVTYKDPSNV-DNVLANGP 376

Query: 70  KSVDGRQI 77
             +D + +
Sbjct: 375 HCIDSKTL 352

 Score = 55.5 bits (132), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 27/82 (32%), Positives = 45/82 (54%)
 Frame = -1

Query: 1   MASDEGKLFVGGLSFDTNEQALEQVFSKYGQISEVVVVKDRETQRSRGFGFVTFENIDDA 60
           M +   K+FVGGLS  T  + ++  F  YG I E  ++ D+ T R RGF FVTF+N +  
Sbjct: 249 MVTKTKKIFVGGLSSSTTVEDIKNYFKAYGTIEEATLMFDKVTSRHRGFAFVTFDN-EST 73

Query: 61  KDAMMAMNGKSVDGRQIRVDQA 82
            D +  ++   ++ + +   +A
Sbjct: 72  VDKVCEIHFHEINSKMVETKKA 7
>23322
          Length = 471

 Score = 56.2 bits (134), Expect = 6e-09,   Method: Compositional matrix adjust.
 Identities = 29/81 (35%), Positives = 51/81 (62%)
 Frame = -2

Query: 7   KLFVGGLSFDTNEQALEQVFSKYGQISEVVVVKDRETQRSRGFGFVTFENIDDAKDAMMA 66
           K+FVGG+  DT E  +   F+++G+I+ V +++D+ T ++RGF FVTF + D    A++ 
Sbjct: 407 KMFVGGVKEDTTEDMIRDTFNEFGEITGVDLIQDKGTGKNRGFCFVTFGDHDSVDKAVLK 228

Query: 67  MNGKSVDGRQIRVDQAGKSSD 87
                ++GRQ+ V +A   +D
Sbjct: 227 KR-HDLNGRQVEVKKAQSKND 168
>02140
          Length = 1796

 Score = 56.2 bits (134), Expect = 7e-09,   Method: Compositional matrix adjust.
 Identities = 26/73 (35%), Positives = 44/73 (60%)
 Frame = +3

Query: 8   LFVGGLSFDTNEQALEQVFSKYGQISEVVVVKDRETQRSRGFGFVTFENIDDAKDAMMAM 67
           LFV  L+  T ++ LE +FS++G I+   V++D +T+ S  + FV FE  +  ++A   M
Sbjct: 807 LFVCKLNPVTTDEDLEMIFSRFGPITSCEVIRDHKTKESLQYAFVEFEKPEHCENAYFKM 986

Query: 68  NGKSVDGRQIRVD 80
           +   +D R+I VD
Sbjct: 987 DNVLIDDRRIHVD 1025
>26197
          Length = 1365

 Score = 55.8 bits (133), Expect = 9e-09,   Method: Compositional matrix adjust.
 Identities = 27/74 (36%), Positives = 47/74 (63%)
 Frame = -2

Query: 4    DEGKLFVGGLSFDTNEQALEQVFSKYGQISEVVVVKDRETQRSRGFGFVTFENIDDAKDA 63
            D+ K+FVGGLS++T+ + L + F K+G+++   +  D ++ +SRGFGFV F+      DA
Sbjct: 1304 DDRKIFVGGLSWETSSKHLREYFEKFGEVTSCTLKTDLDSGKSRGFGFVVFKEAVTV-DA 1128

Query: 64   MMAMNGKSVDGRQI 77
            ++      + GR+I
Sbjct: 1127 VVKNKEHKLQGRKI 1086

 Score = 40.0 bits (92), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 20/74 (27%), Positives = 39/74 (52%)
 Frame = -3

Query: 6    GKLFVGGLSFDTNEQALEQVFSKYGQISEVVVVKDRETQRSRGFGFVTFENIDDAKDAMM 65
            G+ FVG L     ++ +E  F+K+G++  V +  D+   + R F FV F+N D     ++
Sbjct: 1051 GRFFVGKLDPGVPQEDVESYFAKFGKVVNVELPYDKVKDQRRAFCFVEFDN-DKTVKKVL 875

Query: 66   AMNGKSVDGRQIRV 79
                  + G+++R+
Sbjct: 874  EQTSHKIGGQEVRI 833
>03406
          Length = 1292

 Score = 55.5 bits (132), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 27/74 (36%), Positives = 46/74 (62%)
 Frame = +3

Query: 4   DEGKLFVGGLSFDTNEQALEQVFSKYGQISEVVVVKDRETQRSRGFGFVTFENIDDAKDA 63
           D+ K+FVGGLS++T  + L + F K+G+++   +  D ++ +SRGFGFV F+      DA
Sbjct: 234 DDRKIFVGGLSWETXSKHLREYFEKFGEVTSCTLKTDLDSGKSRGFGFVVFKEAATV-DA 410

Query: 64  MMAMNGKSVDGRQI 77
           ++      + GR+I
Sbjct: 411 VVKNKEHKLQGRKI 452

 Score = 38.9 bits (89), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 21/76 (27%), Positives = 40/76 (52%)
 Frame = +3

Query: 7   KLFVGGLSFDTNEQALEQVFSKYGQISEVVVVKDRETQRSRGFGFVTFENIDDAKDAMMA 66
           K+FVG L     ++ +E  F+K+G++  V +  D+   + R F FV F+N D     ++ 
Sbjct: 489 KIFVGKLDPGVPQEDVESYFAKFGKVVNVELPYDKVKDQRRAFCFVEFDN-DKTVKKVLE 665

Query: 67  MNGKSVDGRQIRVDQA 82
                + G+++ V +A
Sbjct: 666 QTSHKIGGQEVDVKKA 713
>39789
          Length = 361

 Score = 53.9 bits (128), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 29/72 (40%), Positives = 44/72 (61%)
 Frame = +1

Query: 8   LFVGGLSFDTNEQALEQVFSKYGQISEVVVVKDRETQRSRGFGFVTFENIDDAKDAMMAM 67
           LFVG LS+DT++ +L+  F      +   + K ++TQ+ RGFGFV F   DDA  A  + 
Sbjct: 94  LFVGNLSYDTDQYSLKDAFPG---ATAARIAKFQDTQKPRGFGFVEFSTPDDAASAFDSG 264

Query: 68  NGKSVDGRQIRV 79
             + VDGRQ+++
Sbjct: 265 E-REVDGRQVKL 297
>30672
          Length = 877

 Score = 53.1 bits (126), Expect = 5e-08,   Method: Compositional matrix adjust.
 Identities = 28/76 (36%), Positives = 42/76 (55%)
 Frame = +3

Query: 7   KLFVGGLSFDTNEQALEQVFSKYGQISEVVVVKDRETQRSRGFGFVTFENIDDAKDAMMA 66
           +L +  L+F   E  +   F K+G ISEV +   ++  RSRGF FV F  +  A+ A+  
Sbjct: 408 RLIIRNLAFKCKEADIRSHFGKFGTISEVTI-PLKQGDRSRGFAFVQFTEVKAAQKAISD 584

Query: 67  MNGKSVDGRQIRVDQA 82
           MNG ++  R + VD A
Sbjct: 585 MNGTAIMDRPVAVDWA 632

 Score = 48.1 bits (113), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 23/68 (33%), Positives = 38/68 (55%), Gaps = 3/68 (4%)
 Frame = +3

Query: 8  LFVGGLSFDTNEQALEQVFSKYGQISEVVVVKDRETQRSRGFGFVTFENIDD---AKDAM 64
          LFV  L F+T+ + L + F + G +    VV  +E  + RGFG+V F  ++D   AKD +
Sbjct: 18 LFVRNLPFETSNEKLLEAFEQVGPLKTAFVVAGKEPGKCRGFGYVQFSMLEDAIKAKDTV 197

Query: 65 MAMNGKSV 72
             +G+ +
Sbjct: 198THCSGRKI 221
>12506
          Length = 1056

 Score = 53.1 bits (126), Expect = 6e-08,   Method: Compositional matrix adjust.
 Identities = 28/77 (36%), Positives = 43/77 (55%)
 Frame = -3

Query: 6    GKLFVGGLSFDTNEQALEQVFSKYGQISEVVVVKDRETQRSRGFGFVTFENIDDAKDAMM 65
            G LF  G   + +++ L   F  +G I ++ +  D ET++ RGF F+ FE  +DA  A+ 
Sbjct: 1054 GSLFTAG---EVDDKVLHAAFLPFGDIVDIQIPLDYETEKHRGFAFIEFELAEDAAAAID 884

Query: 66   AMNGKSVDGRQIRVDQA 82
             MN   + GR IRV+ A
Sbjct: 883  NMNESELFGRTIRVNLA 833
>01937
          Length = 1320

 Score = 53.1 bits (126), Expect = 6e-08,   Method: Compositional matrix adjust.
 Identities = 25/56 (44%), Positives = 33/56 (58%)
 Frame = -1

Query: 1    MASDEGKLFVGGLSFDTNEQALEQVFSKYGQISEVVVVKDRETQRSRGFGFVTFEN 56
            M +   K+FVGGLS  T  +  +  F  YG I E  ++ D+ T R RGF FVTF+N
Sbjct: 1230 MVTKTSKIFVGGLSSSTTVEDXKNYFKAYGTIEEATLMFDKVTSRHRGFAFVTFDN 1063
>04988
          Length = 705

 Score = 52.8 bits (125), Expect = 7e-08,   Method: Compositional matrix adjust.
 Identities = 23/80 (28%), Positives = 48/80 (60%)
 Frame = -3

Query: 7   KLFVGGLSFDTNEQALEQVFSKYGQISEVVVVKDRETQRSRGFGFVTFENIDDAKDAMMA 66
           ++++G L +   E+ +E+ F  YG+++++++          G+GFV FE+  DA DA+  
Sbjct: 649 RVYIGRLPYQAREKDIERFFRGYGRVNDIML--------KNGYGFVEFEDFRDADDAVYE 494

Query: 67  MNGKSVDGRQIRVDQAGKSS 86
           +NGK + G ++ ++ A  +S
Sbjct: 493 LNGKDLCGERVIIEHARGTS 434
>03059
          Length = 1154

 Score = 52.8 bits (125), Expect = 7e-08,   Method: Compositional matrix adjust.
 Identities = 25/72 (34%), Positives = 45/72 (62%), Gaps = 1/72 (1%)
 Frame = -2

Query: 7   KLFVGGLSFDTNEQALEQVFSKYGQISEVVVVKDR-ETQRSRGFGFVTFENIDDAKDAMM 65
           K+ VG L+ + N+  ++++FS YG I  + +  DR     S+G  +V +EN +DA+ A+ 
Sbjct: 667 KVHVGRLTRNVNKDHIQEIFSLYGTIKFIDLPNDRIHPNTSKGHAYVEYENPEDAEKAVK 488

Query: 66  AMNGKSVDGRQI 77
            M+G  +DG++I
Sbjct: 487 YMDGGQIDGQEI 452
>10194
          Length = 1278

 Score = 52.8 bits (125), Expect = 7e-08,   Method: Compositional matrix adjust.
 Identities = 26/83 (31%), Positives = 46/83 (55%)
 Frame = -3

Query: 4   DEGKLFVGGLSFDTNEQALEQVFSKYGQISEVVVVKDRETQRSRGFGFVTFENIDDAKDA 63
           D+  +FVG L FD  E+++   F   G +  + VV+DR+T   +G  ++ F++ D    A
Sbjct: 412 DKRSVFVGNLPFDIEEESVRSHFEDCGDVENIRVVRDRKTNLGKGICYILFKSADSVSLA 233

Query: 64  MMAMNGKSVDGRQIRVDQAGKSS 86
            + +N   ++ RQIRV +   +S
Sbjct: 232 -LKLNNSELEKRQIRVQRCKDAS 167

 Score = 45.1 bits (105), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 28/104 (26%), Positives = 51/104 (49%), Gaps = 17/104 (16%)
 Frame = -3

Query: 2   ASDEGKLFVGGLSFDTNEQALEQVFSKYGQISEV-----------------VVVKDRETQ 44
           A+++  +FVG +   T+++ L ++F ++G+I  V                 V+ KD   +
Sbjct: 724 ANEKRTVFVGNVPLKTDKKKLARLFKQFGKIENVRFRCAPVGDPTTKKRVAVITKDFHEK 545

Query: 45  RSRGFGFVTFENIDDAKDAMMAMNGKSVDGRQIRVDQAGKSSDN 88
           R     ++ F+  + AK A+  +NG  +DG  +RVD A  S  N
Sbjct: 544 RHNISAYICFKEDEAAKQALT-LNGHVIDGLHLRVDSAKLSLKN 416
>23720
          Length = 739

 Score = 52.8 bits (125), Expect = 7e-08,   Method: Compositional matrix adjust.
 Identities = 23/80 (28%), Positives = 48/80 (60%)
 Frame = -1

Query: 7   KLFVGGLSFDTNEQALEQVFSKYGQISEVVVVKDRETQRSRGFGFVTFENIDDAKDAMMA 66
           ++++G L +   E+ +E+ F  YG+++++++          G+GFV FE+  DA DA+  
Sbjct: 682 RVYIGRLPYQAREKDIERFFRGYGRVNDIML--------KNGYGFVEFEDFRDADDAVYE 527

Query: 67  MNGKSVDGRQIRVDQAGKSS 86
           +NGK + G ++ ++ A  +S
Sbjct: 526 LNGKDLCGERVIIEHARGTS 467
>31310
          Length = 469

 Score = 52.4 bits (124), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 25/81 (30%), Positives = 47/81 (58%)
 Frame = -3

Query: 7   KLFVGGLSFDTNEQALEQVFSKYGQISEVVVVKDRETQRSRGFGFVTFENIDDAKDAMMA 66
           +++VG ++F+  E  ++Q F  +G I  V +  D  T + +GF F+ ++  + A+ A+  
Sbjct: 320 RIYVGSINFEIREDTIKQAFLPFGPIKSVNLSWDPITNKHKGFSFIEYDVPEAAQLALEQ 141

Query: 67  MNGKSVDGRQIRVDQAGKSSD 87
           MNG  + GR I+V   G+ S+
Sbjct: 140 MNGVMIGGRNIKV---GRPSN 87
>01278
          Length = 1082

 Score = 52.4 bits (124), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 27/76 (35%), Positives = 43/76 (56%)
 Frame = +2

Query: 10  VGGLSFDTNEQALEQVFSKYGQISEVVVVKDRETQRSRGFGFVTFENIDDAKDAMMAMNG 69
           V  LS DT E  L+++F  +G IS + + KD+ T +S+GF F+ F   +DA  A+  ++G
Sbjct: 647 VTNLSEDTRESDLQELFRPFGPISRIYLAKDKVTGQSKGFAFINFHRREDASRAIAGVSG 826

Query: 70  KSVDGRQIRVDQAGKS 85
              D   + V+ A  S
Sbjct: 827 FGYDHLILNVEWAKPS 874
>00029
          Length = 2204

 Score = 51.2 bits (121), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 26/74 (35%), Positives = 44/74 (59%)
 Frame = -3

Query: 7    KLFVGGLSFDTNEQALEQVFSKYGQISEVVVVKDRETQRSRGFGFVTFENIDDAKDAMMA 66
            K+F+G L  DT+ + L  +F KYG ++E  V+K+        FGFV      +A DA+  
Sbjct: 2133 KIFIGNLGDDTDPEELRALFEKYGSVAECDVLKN--------FGFVHMVKKGEADDAISN 1978

Query: 67   MNGKSVDGRQIRVD 80
            +NG ++ G+++RV+
Sbjct: 1977 LNGYNIGGQRMRVE 1936
>08958
          Length = 680

 Score = 50.4 bits (119), Expect = 4e-07,   Method: Compositional matrix adjust.
 Identities = 27/76 (35%), Positives = 43/76 (56%)
 Frame = +2

Query: 7   KLFVGGLSFDTNEQALEQVFSKYGQISEVVVVKDRETQRSRGFGFVTFENIDDAKDAMMA 66
           +LFVG L+ D +E   +++FS +G++SE  V         RGFGF+  +   +A+ A  A
Sbjct: 71  RLFVGNLTPDVSEDDFKKLFSPFGEVSEAYV------NSGRGFGFIRLDYRHNAEAAKAA 232

Query: 67  MNGKSVDGRQIRVDQA 82
           ++G    GR +RV  A
Sbjct: 233 LDGLQRKGRSLRVRYA 280
>13822
          Length = 963

 Score = 50.4 bits (119), Expect = 4e-07,   Method: Compositional matrix adjust.
 Identities = 31/82 (37%), Positives = 47/82 (57%), Gaps = 2/82 (2%)
 Frame = -1

Query: 3   SDEG--KLFVGGLSFDTNEQALEQVFSKYGQISEVVVVKDRETQRSRGFGFVTFENIDDA 60
           S EG  +L V  + F   E  L Q+   +G I +V ++ +   + S+GFGFVTF +  +A
Sbjct: 357 SPEGPKRLHVSNIPFRFREADLRQLLGPFGTILDVEIIFNE--RGSKGFGFVTFAHSAEA 184

Query: 61  KDAMMAMNGKSVDGRQIRVDQA 82
           + A   MNG  V+GR+I V+ A
Sbjct: 183 ERARDKMNGTVVEGRKIEVNNA 118
>02809
          Length = 1475

 Score = 49.7 bits (117), Expect = 6e-07,   Method: Compositional matrix adjust.
 Identities = 29/69 (42%), Positives = 40/69 (57%)
 Frame = -1

Query: 7    KLFVGGLSFDTNEQALEQVFSKYGQISEVVVVKDRETQRSRGFGFVTFENIDDAKDAMMA 66
            K++VG L     +Q LE  F+KYG +  V V +     R  GF FV FE+  DA+DA+ A
Sbjct: 1331 KVYVGELGHGCAKQELEDKFAKYGPLKNVWVAR-----RPAGFAFVEFEDNRDAEDAVQA 1167

Query: 67   MNGKSVDGR 75
            ++G S D R
Sbjct: 1166 LDG-SADXR 1143
>20488
          Length = 3281

 Score = 47.0 bits (110), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 23/77 (29%), Positives = 44/77 (57%)
 Frame = +2

Query: 3    SDEGKLFVGGLSFDTNEQALEQVFSKYGQISEVVVVKDRETQRSRGFGFVTFENIDDAKD 62
             D   LF+  L  +  +Q L Q+F  +G +    V  D++T  S+ FGFV++++   A+ 
Sbjct: 2699 PDGANLFIYHLPQEFGDQDLMQMFMPFGNVVSAKVFIDKQTNLSKCFGFVSYDSPLAAQA 2878

Query: 63   AMMAMNGKSVDGRQIRV 79
            A+ +MNG  +  ++++V
Sbjct: 2879 AITSMNGFQIGMKRLKV 2929
>03744
          Length = 3486

 Score = 47.0 bits (110), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 23/77 (29%), Positives = 44/77 (57%)
 Frame = -1

Query: 3    SDEGKLFVGGLSFDTNEQALEQVFSKYGQISEVVVVKDRETQRSRGFGFVTFENIDDAKD 62
             D   LF+  L  +  +Q L Q+F  +G +    V  D++T  S+ FGFV++++   A+ 
Sbjct: 3225 PDGANLFIYHLPQEFGDQDLMQMFMPFGNVVSAKVFIDKQTNLSKCFGFVSYDSPLAAQA 3046

Query: 63   AMMAMNGKSVDGRQIRV 79
            A+ +MNG  +  ++++V
Sbjct: 3045 AITSMNGFQIGMKRLKV 2995
>28455
          Length = 573

 Score = 47.0 bits (110), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 26/76 (34%), Positives = 43/76 (56%)
 Frame = -1

Query: 4   DEGKLFVGGLSFDTNEQALEQVFSKYGQISEVVVVKDRETQRSRGFGFVTFENIDDAKDA 63
           ++ KLFV  L F  + +ALE +F ++G++ +V +V  R +  S+G  +V FE  + A  A
Sbjct: 546 EKNKLFVKNLPFTCSAEALETIFKEHGKVKDVRLVTYR-SGASKGLAYVEFETEEMATQA 370

Query: 64  MMAMNGKSVDGRQIRV 79
           +M  +G  V    I V
Sbjct: 369 VMKTDGLQVGDHMISV 322
>05273
          Length = 1009

 Score = 46.6 bits (109), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 19/40 (47%), Positives = 28/40 (70%)
 Frame = -1

Query: 17  TNEQALEQVFSKYGQISEVVVVKDRETQRSRGFGFVTFEN 56
           T + +L + F K+G I E VV+ DR+T +SRG+GFVT  +
Sbjct: 166 TTDHSLREYFDKFGDIDEAVVITDRQTGKSRGYGFVTMAD 47
>14637
          Length = 455

 Score = 46.2 bits (108), Expect = 7e-06,   Method: Compositional matrix adjust.
 Identities = 23/67 (34%), Positives = 39/67 (58%)
 Frame = -1

Query: 3   SDEGKLFVGGLSFDTNEQALEQVFSKYGQISEVVVVKDRETQRSRGFGFVTFENIDDAKD 62
            D   LF+  L  +  +Q L Q+F  +G +    V  D++T  S+ FGFV++++   A+D
Sbjct: 212 PDGSNLFIYHLPQEFGDQDLMQMFMPFGNVISAKVFIDKQTNLSKCFGFVSYDSPMSAQD 33

Query: 63  AMMAMNG 69
           A+ +MNG
Sbjct: 32  AISSMNG 12
>28605
          Length = 697

 Score = 45.4 bits (106), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 25/78 (32%), Positives = 45/78 (57%), Gaps = 1/78 (1%)
 Frame = -3

Query: 7   KLFVGGLSFD-TNEQALEQVFSKYGQISEVVVVKDRETQRSRGFGFVTFENIDDAKDAMM 65
           ++FV  LS D T+E  L+++FSKYG + + +V  +R       +GFV F   ++ + A+ 
Sbjct: 566 RVFVANLSSDETSEAELQELFSKYGNVLDTLVHHNR-------YGFVQFSTEEEGRRAVE 408

Query: 66  AMNGKSVDGRQIRVDQAG 83
           AMNG     ++++ + A 
Sbjct: 407 AMNGYMFYRKKLKCNXAA 354
>11108
          Length = 493

 Score = 45.1 bits (105), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 22/76 (28%), Positives = 43/76 (56%)
 Frame = -1

Query: 1   MASDEGKLFVGGLSFDTNEQALEQVFSKYGQISEVVVVKDRETQRSRGFGFVTFENIDDA 60
           M +   K+F+GG+ +D +EQ+L Q+F  +G I      K+++  + +G+ ++ FE+ D  
Sbjct: 307 MLNYSPKVFLGGIPWDISEQSLIQIFKPFGSIKVEWPGKEQQAAQPKGYVYIIFES-DKQ 131

Query: 61  KDAMMAMNGKSVDGRQ 76
             A+++     VD  Q
Sbjct: 130 VKALLSACVLQVDDSQ 83
>14258
          Length = 1063

 Score = 44.7 bits (104), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 20/61 (32%), Positives = 39/61 (63%)
 Frame = +2

Query: 19  EQALEQVFSKYGQISEVVVVKDRETQRSRGFGFVTFENIDDAKDAMMAMNGKSVDGRQIR 78
           +Q L Q+F  +G +    V  D++T  S+ FGFV++++   A+DA+ +MNG  +  ++++
Sbjct: 101 DQDLMQMFMPFGNVISAKVFIDKQTNLSKCFGFVSYDSPMSAQDAISSMNGFQIGMKRLK 280

Query: 79  V 79
           V
Sbjct: 281 V 283
>17775
          Length = 1282

 Score = 44.7 bits (104), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 25/80 (31%), Positives = 44/80 (55%)
 Frame = -2

Query: 8   LFVGGLSFDTNEQALEQVFSKYGQISEVVVVKDRETQRSRGFGFVTFENIDDAKDAMMAM 67
           L+V  L    +++ L + FS +G I+   ++   E  RS+GFGFV F + ++A  A+  M
Sbjct: 336 LYVKNLDDSIDDERLRKEFSNFGTITSAKIMT--EGGRSKGFGFVCFSSPEEATKAVTEM 163

Query: 68  NGKSVDGRQIRVDQAGKSSD 87
           NG+ +  + + V  A +  D
Sbjct: 162 NGRIIVAKPLYVALAQRKED 103

 Score = 42.7 bits (99), Expect = 7e-05,   Method: Compositional matrix adjust.
 Identities = 24/74 (32%), Positives = 41/74 (55%)
 Frame = -2

Query: 6   GKLFVGGLSFDTNEQALEQVFSKYGQISEVVVVKDRETQRSRGFGFVTFENIDDAKDAMM 65
           G +F+  L    + +AL   FS +G I    +  D   Q S+G+GFV FE  + A+ A+ 
Sbjct: 930 GNVFIKNLDKTIDNKALYDTFSAFGNILSCKIACDE--QGSKGYGFVHFETEEAARQAID 757

Query: 66  AMNGKSVDGRQIRV 79
            +NG  ++G+++ V
Sbjct: 756 KVNGMLLNGKKVYV 715

 Score = 38.9 bits (89), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 19/43 (44%), Positives = 28/43 (65%)
 Frame = -2

Query: 45  RSRGFGFVTFENIDDAKDAMMAMNGKSVDGRQIRVDQAGKSSD 87
           +SRGFGFV+FE  + A+ A+  +NG  V GR I   +A K ++
Sbjct: 537 KSRGFGFVSFEEPEGAEKAVDEINGTEVSGRIIYCGRAQKRAE 409
>29364
          Length = 1126

 Score = 44.3 bits (103), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 22/64 (34%), Positives = 37/64 (57%)
 Frame = +1

Query: 19 EQALEQVFSKYGQISEVVVVKDRETQRSRGFGFVTFENIDDAKDAMMAMNGKSVDGRQIR 78
          E+ LE+ F  YG+  ++++          G+GFV FE+  DA DA+  +NGK + G ++ 
Sbjct: 7  ERDLERFFKGYGRTRDILI--------KNGYGFVEFEDYRDADDAVYELNGKELLGERVV 162

Query: 79 VDQA 82
          V+ A
Sbjct: 163VEPA 174
>12350
          Length = 975

 Score = 43.9 bits (102), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 25/72 (34%), Positives = 37/72 (51%)
 Frame = -2

Query: 8   LFVGGLSFDTNEQALEQVFSKYGQISEVVVVKDRETQRSRGFGFVTFENIDDAKDAMMAM 67
           L V GL + + E  L   FS++G +  V V KD +T +S+GFGF+ F   +     M   
Sbjct: 614 LIVLGLPWKSTEDDLRSYFSQFGDLLMVQVKKDPKTGQSKGFGFIRFAEYESQLKCMAQR 435

Query: 68  NGKSVDGRQIRV 79
           +   +DGR   V
Sbjct: 434 H--MIDGRWCDV 405

 Score = 33.9 bits (76), Expect = 0.037,   Method: Compositional matrix adjust.
 Identities = 18/55 (32%), Positives = 30/55 (54%)
 Frame = -2

Query: 7   KLFVGGLSFDTNEQALEQVFSKYGQISEVVVVKDRETQRSRGFGFVTFENIDDAK 61
           K+FVG  + D     L Q FSK+G++ +V + +       R F FV+F + + A+
Sbjct: 359 KIFVGRCTDDMTADDLRQFFSKFGEVVDVFIPRP-----FRAFAFVSFADPEVAQ 210
>21527
          Length = 416

 Score = 43.9 bits (102), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 24/72 (33%), Positives = 43/72 (59%)
 Frame = -3

Query: 16  DTNEQALEQVFSKYGQISEVVVVKDRETQRSRGFGFVTFENIDDAKDAMMAMNGKSVDGR 75
           D  +++L  +FS++GQI ++V +K   T + RG  FV F+ I+ A +A+ +M G     +
Sbjct: 408 DELKKSLYAIFSQFGQILDIVAMK---TLKMRGQAFVIFKEINSAANALRSMQGFPFYDK 238

Query: 76  QIRVDQAGKSSD 87
            +R+  + K SD
Sbjct: 237 PMRIQFSKKDSD 202
>02502
          Length = 1557

 Score = 43.5 bits (101), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 21/80 (26%), Positives = 42/80 (52%)
 Frame = -3

Query: 8    LFVGGLSFDTNEQALEQVFSKYGQISEVVVVKDRETQRSRGFGFVTFENIDDAKDAMMAM 67
            ++ GG++    E+ +   F  +G I EV + KD      +GF F+ F N D A +A+  +
Sbjct: 1435 VYCGGVNNGLTEELMHNTFKDFGSILEVRIFKD------KGFAFIRFNNKDAATNAICTI 1274

Query: 68   NGKSVDGRQIRVDQAGKSSD 87
            +G  ++ + +R     +S++
Sbjct: 1273 HGTVINDQVVRCSWGKESNE 1214
>09968
          Length = 2913

 Score = 42.0 bits (97), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 21/74 (28%), Positives = 38/74 (51%)
 Frame = -1

Query: 8    LFVGGLSFDTNEQALEQVFSKYGQISEVVVVKDRETQRSRGFGFVTFENIDDAKDAMMAM 67
            L+V GLS  T    L+ +F K+G++    VV +  +     FGFVT  + D+    +  +
Sbjct: 1386 LWVSGLSSSTRATDLKSLFGKHGKVIGAKVVTNTRSPGRLCFGFVTMASADETTKCIQHL 1207

Query: 68   NGKSVDGRQIRVDQ 81
            +   + G+ I V++
Sbjct: 1206 HRTELHGKMISVER 1165
>02343
          Length = 1715

 Score = 41.6 bits (96), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 18/71 (25%), Positives = 39/71 (54%)
 Frame = -2

Query: 8    LFVGGLSFDTNEQALEQVFSKYGQISEVVVVKDRETQRSRGFGFVTFENIDDAKDAMMAM 67
            L++ GLS +T ++ L  +   +G I+    + D+ T + +G+GFV F+    A+ A+ A+
Sbjct: 1258 LYIRGLSPNTTDKDLVNLCQHFGTITSTKAIIDQTTNKCKGYGFVDFDAPGAAERAVQAL 1079

Query: 68   NGKSVDGRQIR 78
              + +  +  +
Sbjct: 1078 QAQGIQAQMAK 1046
>11579
          Length = 1307

 Score = 40.8 bits (94), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 19/37 (51%), Positives = 26/37 (70%)
 Frame = +3

Query: 46 SRGFGFVTFENIDDAKDAMMAMNGKSVDGRQIRVDQA 82
          SRGF FV F +  DA+DAM +M+G  +DGR++R   A
Sbjct: 3  SRGFAFVRFYDRRDAEDAMDSMDGALLDGREVRCQMA 113
>03200
          Length = 657

 Score = 40.8 bits (94), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 24/75 (32%), Positives = 38/75 (50%)
 Frame = -1

Query: 8   LFVGGLSFDTNEQALEQVFSKYGQISEVVVVKDRETQRSRGFGFVTFENIDDAKDAMMAM 67
           ++V G+     E  L+  FS +G I  + +      +R R  GFVTFE ++ A  A+  M
Sbjct: 480 VYVHGIG--VTEDILKSAFSNFGNIVNINI------ERERNNGFVTFEKMESADQAIANM 325

Query: 68  NGKSVDGRQIRVDQA 82
           NG  +   Q++V  A
Sbjct: 324 NGSMISNVQLKVMMA 280
>11126
          Length = 1061

 Score = 40.0 bits (92), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 20/72 (27%), Positives = 35/72 (48%)
 Frame = -3

Query: 8   LFVGGLSFDTNEQALEQVFSKYGQISEVVVVKDRETQRSRGFGFVTFENIDDAKDAMMAM 67
           ++VG + +    + LEQ F   G ++ V ++ D+ +   +GF +V F + D    A    
Sbjct: 624 VYVGNVDYGATAEELEQHFHGCGSVNRVTILCDKYSGHPKGFAYVEFADKDSVVTAKCTG 445

Query: 68  NGKSVDGRQIRV 79
                 GRQI+V
Sbjct: 444 MDSLFRGRQIKV 409
>00556
          Length = 2189

 Score = 39.3 bits (90), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 19/76 (25%), Positives = 39/76 (51%)
 Frame = +3

Query: 7   KLFVGGLSFDTNEQALEQVFSKYGQISEVVVVKDRETQRSRGFGFVTFENIDDAKDAMMA 66
           K+F+GGL    +E  ++++   +G +    +V+D  T  S+GF F  + +      A   
Sbjct: 762 KIFMGGLPSYLSEDQMKELLLSFGPLKSFNLVRDNATGLSKGFAFCEYLDPSVTDQACAG 941

Query: 67  MNGKSVDGRQIRVDQA 82
           +NG  +  +++ V +A
Sbjct: 942 LNGMQLGDKKLIVQRA 989
>25691
          Length = 768

 Score = 38.9 bits (89), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 16/52 (30%), Positives = 32/52 (61%)
 Frame = -2

Query: 37  VVKDRETQRSRGFGFVTFENIDDAKDAMMAMNGKSVDGRQIRVDQAGKSSDN 88
           +++D+ T +S G+GFV ++  +DA  A+  +NG  +  + I+V  A  S ++
Sbjct: 425 LIRDKPTGQSLGYGFVNYKRQEDADKAIHTLNGLRLQNKTIKVSLARPSCES 270
>25950
          Length = 417

 Score = 38.9 bits (89), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 24/90 (26%), Positives = 46/90 (51%), Gaps = 5/90 (5%)
 Frame = -2

Query: 4   DEGKLFVGGLSFDTNEQALEQVFSKYGQISEVVVVKDRETQRSRGFGFVTFENIDDAKDA 63
           D   ++VG + +  + + LE  F   G I+ V ++ ++     +GF ++ F + +  + A
Sbjct: 287 DTRSVYVGNVDYGASAEELEAHFHGCGTINRVTILCNKADGHPKGFAYIEFGSKEYVETA 108

Query: 64  MMAMNGKSVDGRQIRV-----DQAGKSSDN 88
            +AMN     GRQI+V     ++ G S+ N
Sbjct: 107 -LAMNETLFRGRQIKVMTKRTNRPGLSTTN 21
>28652
          Length = 918

 Score = 38.5 bits (88), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 22/72 (30%), Positives = 39/72 (54%)
 Frame = -2

Query: 8   LFVGGLSFDTNEQALEQVFSKYGQISEVVVVKDRETQRSRGFGFVTFENIDDAKDAMMAM 67
           L+V  L+ D  E  L++ F  YG++  V  +KD        +GFV +E+ +DA  A+  +
Sbjct: 194 LYVRNLTGDVTEDDLKEKFGAYGKVERVKKIKD--------YGFVHYEDREDALKALDDL 39

Query: 68  NGKSVDGRQIRV 79
           +G+ +   +I V
Sbjct: 38  HGEKIGNLEIDV 3

 Score = 35.0 bits (79), Expect = 0.016,   Method: Compositional matrix adjust.
 Identities = 19/74 (25%), Positives = 40/74 (54%), Gaps = 1/74 (1%)
 Frame = -2

Query: 8   LFVGGLSFDTNEQALEQVFSKYGQISEVVVVKDRETQRSRGFGFVTFENIDDAKDAMMAM 67
           +F G +  D  E  L  +F   G I ++ ++ D  +  +RG+ FVT+   + A +A+   
Sbjct: 725 VFCGKIPRDIFEDELIPLFEDCGTIWDLRLMMDPVSNLNRGYCFVTYTTKEAAAEAVKQH 546

Query: 68  NGKSV-DGRQIRVD 80
           +G  +  G++++V+
Sbjct: 545 DGYEIRKGKKLKVN 504
>23655
          Length = 929

 Score = 37.7 bits (86), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 16/43 (37%), Positives = 30/43 (69%)
 Frame = -1

Query: 7   KLFVGGLSFDTNEQALEQVFSKYGQISEVVVVKDRETQRSRGF 49
           K+FVGG+  DT E  +   F+++G+I+ V +++D+ T ++R F
Sbjct: 902 KMFVGGVKEDTTEDMIRDTFNEFGEITGVDLIQDKGTGKNRDF 774
>33504
          Length = 282

 Score = 37.4 bits (85), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 15/38 (39%), Positives = 25/38 (65%)
 Frame = +1

Query: 4   DEGKLFVGGLSFDTNEQALEQVFSKYGQISEVVVVKDR 41
           D   +F+GGL +D  E  +  VFS+YG+I  + +V+D+
Sbjct: 163 DSAWVFIGGLPYDLTEGDIICVFSQYGEIVNINLVRDK 276
>19556
          Length = 917

 Score = 36.6 bits (83), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 24/79 (30%), Positives = 38/79 (48%), Gaps = 1/79 (1%)
 Frame = -1

Query: 9   FVGGLSFDTNEQALEQVFSKYGQISEVVVVKDRETQRSRGFGFVTFENIDDA-KDAMMAM 67
           F+GGL     E+ L + FS++GQ+S V +        SR F +V     ++  K    A 
Sbjct: 821 FIGGLVKGVTEEELMEKFSRFGQVSNVDIKTRTNGIDSRTFAYVNLTAEENGFKKCFTAY 642

Query: 68  NGKSVDGRQIRVDQAGKSS 86
           N     G Q+++  A +SS
Sbjct: 641 NNTKWKGGQLKLQYAKESS 585
>28372
          Length = 398

 Score = 34.7 bits (78), Expect = 0.019,   Method: Compositional matrix adjust.
 Identities = 17/34 (50%), Positives = 23/34 (67%)
 Frame = -2

Query: 47  RGFGFVTFENIDDAKDAMMAMNGKSVDGRQIRVD 80
           +GFGFVTF +  +A+ A   MNG  V+GR+I V 
Sbjct: 259 QGFGFVTFAHSAEAERARDKMNGTVVEGRKIEVP 158
>25431
          Length = 1623

 Score = 32.0 bits (71), Expect = 0.12,   Method: Compositional matrix adjust.
 Identities = 16/52 (30%), Positives = 26/52 (50%)
 Frame = +2

Query: 21  ALEQVFSKYGQISEVVVVKDRETQRSRGFGFVTFENIDDAKDAMMAMNGKSV 72
            +  + S YGQ+  +V+ K    Q       V F+N++ AK A  ++NG  V
Sbjct: 101 VMHTICSPYGQVLRIVIFKKNGVQT-----MVEFDNLESAKRAKQSLNGADV 241
>35379
          Length = 534

 Score = 32.0 bits (71), Expect = 0.13,   Method: Compositional matrix adjust.
 Identities = 19/43 (44%), Positives = 24/43 (55%), Gaps = 5/43 (11%)
 Frame = +1

Query: 23 EQVFSKYGQISEVVVVKD-----RETQRSRGFGFVTFENIDDA 60
          E VFS +G       VKD      E +  +G+GFVTFEN +DA
Sbjct: 37 EAVFSAFGP------VKDAK**QTELECPKGYGFVTFENQEDA 147
>25632
          Length = 864

 Score = 32.0 bits (71), Expect = 0.13,   Method: Compositional matrix adjust.
 Identities = 16/56 (28%), Positives = 29/56 (51%)
 Frame = -2

Query: 25  VFSKYGQISEVVVVKDRETQRSRGFGFVTFENIDDAKDAMMAMNGKSVDGRQIRVD 80
              KYG + E  V+K+        +GFV      +A  A+  +NG ++ G+++RV+
Sbjct: 710 CLEKYGTVEECDVLKN--------YGFVHMPTKSEASAAITNLNGYNIKGQRMRVE 567
>13457
          Length = 4857

 Score = 32.0 bits (71), Expect = 0.14,   Method: Compositional matrix adjust.
 Identities = 14/36 (38%), Positives = 24/36 (66%)
 Frame = -2

Query: 44   QRSRGFGFVTFENIDDAKDAMMAMNGKSVDGRQIRV 79
            Q  + FGFV+F+N   A+ A+ AMNG  +  ++++V
Sbjct: 2309 QPEQMFGFVSFDNPASAQAAIQAMNGFQIGMKRLKV 2202
>38650
          Length = 655

 Score = 29.6 bits (65), Expect = 0.66,   Method: Compositional matrix adjust.
 Identities = 12/29 (41%), Positives = 17/29 (58%)
 Frame = -2

Query: 53  TFENIDDAKDAMMAMNGKSVDGRQIRVDQ 81
            FE +  AK   + M GKS++GR  R+D 
Sbjct: 639 VFERLSAAKKRKLMMEGKSMEGRPARLDH 553
>02064
          Length = 1195

 Score = 29.3 bits (64), Expect = 0.76,   Method: Compositional matrix adjust.
 Identities = 25/79 (31%), Positives = 36/79 (45%), Gaps = 2/79 (2%)
 Frame = +1

Query: 3   SDEGKLFVGGLSFDTNEQALEQVFSKYGQI--SEVVVVKDRETQRSRGFGFVTFENIDDA 60
            D   + V  L +    Q L + F + G +  SE+ + K R T    G G V F   DDA
Sbjct: 70  PDNCTVQVKNLPYAITWQDLRERFQEIGVVKYSEITMDKGRST----GQGLVRFATEDDA 237

Query: 61  KDAMMAMNGKSVDGRQIRV 79
             A+ +M+    +GR I V
Sbjct: 238 VRAINSMDRTRYEGRTIGV 294
>35767
          Length = 564

 Score = 29.3 bits (64), Expect = 0.91,   Method: Compositional matrix adjust.
 Identities = 20/60 (33%), Positives = 28/60 (46%), Gaps = 3/60 (5%)
 Frame = +1

Query: 8   LFVGGLSFDTNEQALEQVFSKYGQISEVVVVKDRETQRSRGFGFVTFEN---IDDAKDAM 64
           LF+  L  +TNE  L  +F+++    EV +V  R         FV FE       AKDA+
Sbjct: 268 LFITNLPEETNEMMLSMLFNQFPGFKEVRLVPGRHD-----IAFVEFETDVQAGAAKDAL 432
>19980
          Length = 450

 Score = 28.9 bits (63), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 18/47 (38%), Positives = 26/47 (55%)
 Frame = -2

Query: 17  TNEQALEQVFSKYGQISEVVVVKDRETQRSRGFGFVTFENIDDAKDA 63
           TNE+ L  +FSK G I++   +K     + R F FV F   ++AK A
Sbjct: 152 TNEKMLRDLFSKKGTITD-CSLKHTADGKFRRFAFVGFSCEEEAKTA 15
>12096
          Length = 1585

 Score = 28.9 bits (63), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 21/65 (32%), Positives = 31/65 (47%)
 Frame = -3

Query: 8    LFVGGLSFDTNEQALEQVFSKYGQISEVVVVKDRETQRSRGFGFVTFENIDDAKDAMMAM 67
            + + GLS    E  + Q   + G   + V    R T  SRGFGFV F++  +A+  M   
Sbjct: 1217 ILLRGLSNTLVENDIIQELIRIGMPPKDVRFMRRVTGASRGFGFVEFQSQSEAQRWMDHN 1038

Query: 68   NGKSV 72
             G+ V
Sbjct: 1037 QGQVV 1023
>15752
          Length = 728

 Score = 27.7 bits (60), Expect = 2.4,   Method: Compositional matrix adjust.
 Identities = 12/39 (30%), Positives = 23/39 (58%)
 Frame = +3

Query: 18  NEQALEQVFSKYGQISEVVVVKDRETQRSRGFGFVTFEN 56
           +E  L  +FS+YGQIS +++     + + +G   + FE+
Sbjct: 171 DEDDLSVLFSRYGQISNIII-----SSKKKGAAIIEFES 272
>30934
          Length = 809

 Score = 26.6 bits (57), Expect = 5.0,   Method: Compositional matrix adjust.
 Identities = 14/52 (26%), Positives = 28/52 (53%)
 Frame = +1

Query: 28 KYGQISEVVVVKDRETQRSRGFGFVTFENIDDAKDAMMAMNGKSVDGRQIRV 79
          K G ++++ +  D  T++ +GF  VTF   + A  A M ++ +   GR + +
Sbjct: 22 KGGPVTDLDLPVDPITKKIKGFAHVTFMFPEHAVKARMELDRQGFRGRMLHI 177
>09736
          Length = 1319

 Score = 26.6 bits (57), Expect = 5.0,   Method: Compositional matrix adjust.
 Identities = 15/39 (38%), Positives = 24/39 (61%), Gaps = 1/39 (2%)
 Frame = -2

Query: 45   RSRGFGFVTFENIDDAKDAMMAMNGKSVDGRQ-IRVDQA 82
            +S+GFGFV F   +D + A++ M   +  GR+ I+V  A
Sbjct: 1273 KSKGFGFVRFSEENDQQRALVEMQHMTGIGRRPIKVGLA 1157
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|70778810|ref|NP_001020529.1| kinesin light chain 1
isoform 1B [Mus musculus]
         (550 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

29651                                                                  87   2e-17
25956                                                                  30   2.1  
>29651
          Length = 414

 Score = 86.7 bits (213), Expect = 2e-17,   Method: Compositional matrix adjust.
 Identities = 44/75 (58%), Positives = 62/75 (82%), Gaps = 1/75 (1%)
 Frame = -3

Query: 15  KLENVTQDEIISKTKQVIQGLEALKNEHNSILQSLLETLKCLKKDD-ESNLVEEKSSMIR 73
           K+  V+QDEI + TK V+QGLE LKNEH+ IL SLL +LK +++++ +S+LVEEK++++R
Sbjct: 229 KMTAVSQDEIATNTKTVVQGLETLKNEHHQILNSLLSSLKTIQQENGDSSLVEEKTNILR 50

Query: 74  KSLEMLELGLSEAQV 88
            SLE LELG+SEAQV
Sbjct: 49  ASLETLELGVSEAQV 5
>25956
          Length = 823

 Score = 30.4 bits (67), Expect = 2.1,   Method: Compositional matrix adjust.
 Identities = 11/26 (42%), Positives = 18/26 (69%)
 Frame = -2

Query: 384 NNLASCYLKQGKFKQAETLYKEILTR 409
           N  A+C++ QG+F  AET+ +E L +
Sbjct: 546 NGQAACFMAQGRFDDAETVLQEALDK 469
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|7305305|ref|NP_038892.1| N-myc downstream regulated
gene 2 isoform 1 [Mus musculus]
         (371 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

34081                                                                  86   2e-17
29933                                                                  48   7e-06
11512                                                                  32   0.37 
37884                                                                  28   4.2  
36643                                                                  28   7.6  
>34081
          Length = 315

 Score = 85.9 bits (211), Expect = 2e-17,   Method: Compositional matrix adjust.
 Identities = 39/101 (38%), Positives = 60/101 (59%)
 Frame = +2

Query: 61  KRPAIFTYHDVGLNYKSCFQPLFRFGDMQEIIQNFVRVHVDAPGMEEGAPVFPLGYQYPS 120
            +PAI T+HD+GLN+ +CFQ  F F DMQ I+++F   HV+APG EE A      + YP+
Sbjct: 8   SKPAILTFHDIGLNHVTCFQGFFSFSDMQPILRHFCVFHVNAPGQEESALYLKPEFVYPT 187

Query: 121 LDQLADMIPCILQYLNFSTXXXXXXXXXXYILSRYALNHPD 161
           +DQLA+ +  ++++    +           +L+RY L H D
Sbjct: 188 MDQLAEGVHHVVEHYGLKSIIGFGVGAGANVLTRYELAHQD 310
>29933
          Length = 346

 Score = 47.8 bits (112), Expect = 7e-06,   Method: Compositional matrix adjust.
 Identities = 23/94 (24%), Positives = 46/94 (48%), Gaps = 7/94 (7%)
 Frame = +3

Query: 116 YQYPSLDQLADMIPCILQYLNFSTXXXXXXXXXXYILSRYALNHPDTVEGLVLINIDPNA 175
           + YP+++QLA+ +  ++++ +              +L+RY L H D ++ LVL+N     
Sbjct: 63  FVYPTMEQLAEAVHAVVEHYDLKCIIGFGVGAGANVLARYELAHHDRLDSLVLVNPLATQ 242

Query: 176 KGWMDWAAHKLTG-------LTSSIPDMILGHLF 202
            GW++W   K+         +T+   + +L H F
Sbjct: 243 AGWVEWGYQKMNSWYLLGGQVTNFTEEYLLWHWF 344
>11512
          Length = 1006

 Score = 32.0 bits (71), Expect = 0.37,   Method: Compositional matrix adjust.
 Identities = 18/58 (31%), Positives = 28/58 (48%)
 Frame = -3

Query: 172 DPNAKGWMDWAAHKLTGLTSSIPDMILGHLFSQEELSGNSELIQKYRGIIQHAPNLEN 229
           + NA+ + D     +   T  I D   GH F  E ++G  EL+  +  ++QH   LEN
Sbjct: 728 EANARSFTDEEFEDMIKSTXRI-DFTYGHFFDVEIVNG--ELLAAFEXLVQHVQRLEN 564
>37884
          Length = 690

 Score = 28.5 bits (62), Expect = 4.2,   Method: Compositional matrix adjust.
 Identities = 13/23 (56%), Positives = 17/23 (73%)
 Frame = -1

Query: 117 QYPSLDQLADMIPCILQYLNFST 139
           Q+PS DQL + IP I Q+L+F T
Sbjct: 372 QFPSKDQLHEKIPLINQFLSFMT 304
>36643
          Length = 601

 Score = 27.7 bits (60), Expect = 7.6,   Method: Compositional matrix adjust.
 Identities = 20/62 (32%), Positives = 26/62 (41%)
 Frame = -2

Query: 60  PKRPAIFTYHDVGLNYKSCFQPLFRFGDMQEIIQNFVRVHVDAPGMEEGAPVFPLGYQYP 119
           P RPA F        + S  +    F D     ++  + H D PG   G PVFP G+   
Sbjct: 177 PLRPAFF--------FLSV*ERRNEFPDEPGSTKDDAKEHEDGPGTLLGTPVFPCGHSSC 22

Query: 120 SL 121
           SL
Sbjct: 21  SL 16
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|7657357|ref|NP_056596.1| nucleosome assembly protein
1-like 1 isoform 2 [Mus musculus]
         (391 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

10418                                                                  87   2e-17
25304                                                                  47   1e-05
28559                                                                  28   7.8  
>10418
          Length = 974

 Score = 86.7 bits (213), Expect = 2e-17,   Method: Compositional matrix adjust.
 Identities = 53/135 (39%), Positives = 58/135 (42%), Gaps = 3/135 (2%)
 Frame = +1

Query: 212 FVLEFHFEPNDYFTNEVLTKTYRMRSEXXXXXXXXXXGPEIMGCTGCQIDWXXXXXXXXX 271
           F LEFHFEPN+YFT  VLTK Y MR E          GPEI+ C GC I W         
Sbjct: 1   FTLEFHFEPNEYFTESVLTKQYTMRFEQDPTDPFSYEGPEIIKCVGCPITWNKGKNVTVK 180

Query: 272 XXXXXXXXXXXXXXXXXXXXXSNDSFFNFF---APPEVPENGXXXXXXXXXXXXXXXXGH 328
                                 NDSFFNFF     PE                     GH
Sbjct: 181 VVKKKQKHKGKGLTRTVTKTVQNDSFFNFFDPPEVPEPENEDDVDEDMEQLLATDFEIGH 360

Query: 329 FLRERIIPRSVLYFT 343
           F+RERI+PR+VLYFT
Sbjct: 361 FIRERIVPRAVLYFT 405
>25304
          Length = 525

 Score = 47.4 bits (111), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 41/169 (24%), Positives = 69/169 (40%), Gaps = 1/169 (0%)
 Frame = -2

Query: 68  ESLPKVVKRRVNALKNLQVKCAQIEAKFYEEVHDLERKYAVLYQPLFDKRFEIINAIYXX 127
           E   K  +  +  +  +Q    ++  +  EE+  +E+KY  L QP F KR ++I+     
Sbjct: 476 EQADKDQQEAIERIDEVQNDIDRLNEQASEEILTVEQKYNKLRQPFFKKRQDLIS----- 312

Query: 128 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGIPEFWLTVFKNVDLLSDMVQE 187
                                                  IP FW+T F N   +S ++ E
Sbjct: 311 --------------------------------------KIPNFWVTSFVNHPQVSALLTE 246

Query: 188 HDEPILKHLKDIKVK-FSDAGQPMSFVLEFHFEPNDYFTNEVLTKTYRM 235
            DE  L+ L  ++V+ F D      + ++FHFE N +F NEV+ K + +
Sbjct: 245 DDEEALQFLSVVEVQEFEDIK--SGYTIKFHFESNPFFDNEVICKEFHL 105
>28559
          Length = 927

 Score = 27.7 bits (60), Expect = 7.8,   Method: Compositional matrix adjust.
 Identities = 13/35 (37%), Positives = 21/35 (60%)
 Frame = -3

Query: 168 PEFWLTVFKNVDLLSDMVQEHDEPILKHLKDIKVK 202
           P FW+T F N   +S ++ E DE  L+ L  ++V+
Sbjct: 754 PNFWVTSFVNHPQVSALLTEDDEEALQFLSMVEVQ 650
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6755364|ref|NP_035424.1| RNA polymerase II
transcriptional coactivator [Mus musculus]
         (127 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

08804                                                                  83   3e-17
>08804
          Length = 930

 Score = 83.2 bits (204), Expect = 3e-17,   Method: Compositional matrix adjust.
 Identities = 34/65 (52%), Positives = 54/65 (83%)
 Frame = -1

Query: 63  MFQIGKMRYVSVRDFKGKILIDIREYWMDSEGEMKPGRKGISLNMEQWSQLKEQISDIDD 122
           MFQ+ +MR+ +V +F+GK+L+ +REY+ + +G M PG+KGISL++EQW+ LK+ I +ID+
Sbjct: 927 MFQLARMRFATVSEFRGKVLVSVREYY-EKDGNMLPGKKGISLSLEQWNALKDHIDNIDE 751

Query: 123 AVRKL 127
           AVRK+
Sbjct: 750 AVRKM 736
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|159032014|ref|NP_666224.3| GRB10 interacting GYF
protein 2 isoform a [Mus musculus]
         (1291 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

01923                                                                  87   4e-17
02468                                                                  84   4e-16
32485                                                                  36   0.095
>01923
          Length = 1390

 Score = 87.0 bits (214), Expect = 4e-17,   Method: Compositional matrix adjust.
 Identities = 52/154 (33%), Positives = 76/154 (49%), Gaps = 3/154 (1%)
 Frame = +1

Query: 1138 QDGFTQWCEQMLHALNTANNLDVPTFVSFLKEVESPYEVHDYTRAYLGDTSEAKEFAKQF 1197
            +D FT WCE  L  +N    +D+ TFVSFL+ V+SP E+ DY R+YLG+   A+EFAKQF
Sbjct: 811  KDDFTVWCEAFLEGINA--QIDIETFVSFLQAVDSPSEIQDYVRSYLGEGKHAREFAKQF 984

Query: 1198 LERRAKQKVNXXXXXXXXXXXXXDSVWG--MNHSTLHSVFXXXXXXXXXXXFEAVQSGXX 1255
            +E+R    +              +S+WG     +T                  A ++   
Sbjct: 985  MEKRT---MYRNKAASELQAEEEESIWGPAPARNTAAPAMRLLHPAQPVMGDTAPKAKGG 1155

Query: 1256 XXXXXMVRAD-PSLLGFSVNASSERLNMGEIETL 1288
                 M + D  SLLGF+V+    R N G+IE++
Sbjct: 1156 KKKKKMQKLDGSSLLGFTVHKDPNRTNAGDIESI 1257
>02468
          Length = 2514

 Score = 84.0 bits (206), Expect = 4e-16,   Method: Compositional matrix adjust.
 Identities = 40/96 (41%), Positives = 52/96 (54%)
 Frame = -3

Query: 496  AEKMVAYLQDSALDDERLTSKLQEHRAKGVSIPLMHEAMQKWYYKDPQGEIQGPFNNQEM 555
            A  M +  Q   L D     K +   A   S  +  E    W+Y DPQ EIQGPF  ++M
Sbjct: 1360 ASAMPSMPQGVTLSDIFSNEKTEAKNATATS--MTDENALMWFYTDPQDEIQGPFTGEKM 1187

Query: 556  AEWFQAGYFTMSLLVKRACDESFQPLGDIMKMWGRV 591
            A WF AG+F  +LLVKR CD  FQP+ D++K  G +
Sbjct: 1186 ANWFSAGFFNENLLVKRGCDNLFQPIEDLIKQCGYI 1079

 Score = 58.9 bits (141), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 31/61 (50%), Positives = 37/61 (60%)
 Frame = -1

Query: 5    TQTLNFGPEWLRALSSGGSITSPPLSPALPKYKLADYRYGREEMLALFLKDYKIPFDLLE 64
            T T+NFGPEWLR  +  G   +        K+KLA+YRYGREEMLALF   Y+ P   L 
Sbjct: 2397 TDTMNFGPEWLRTHAESGQAVASS-----SKFKLAEYRYGREEMLALFQDRYE-PAAFLR 2236

Query: 65   K 65
            K
Sbjct: 2235 K 2233
>32485
          Length = 694

 Score = 36.2 bits (82), Expect = 0.095,   Method: Compositional matrix adjust.
 Identities = 19/49 (38%), Positives = 23/49 (46%), Gaps = 9/49 (18%)
 Frame = +1

Query: 286 LPEWCLEDAEEEMGTFDSSGAF---------LSLKKVQKEPIPEEQEMD 325
           LPEW +E+  E  GTFDSSGAF         L +K +       E   D
Sbjct: 277 LPEWAMENPSEMGGTFDSSGAFHGETVDSEQLQVKNINNNSKTSEHAAD 423
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|16945962|ref|NP_035416.1| rabphilin 3A [Mus musculus]
         (681 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

29179                                                                  86   4e-17
30040                                                                  73   4e-13
31935                                                                  65   8e-11
16549                                                                  61   1e-09
01494                                                                  49   7e-06
14539                                                                  47   3e-05
26525                                                                  47   4e-05
25445                                                                  37   0.036
30757                                                                  35   0.087
17357                                                                  34   0.15 
13896                                                                  34   0.25 
26304                                                                  33   0.32 
34631                                                                  30   2.8  
14132                                                                  30   2.9  
01053                                                                  28   8.6  
>29179
          Length = 1113

 Score = 86.3 bits (212), Expect = 4e-17,   Method: Compositional matrix adjust.
 Identities = 47/116 (40%), Positives = 63/116 (54%)
 Frame = -3

Query: 380 LGALEFSLLYDQDNSNLQCTIIRAKGLKPMDSNGLADPYVKLHLLPGASKSNKLRTKTLR 439
           LG ++F L+YD  N  L   IIRA  L   D  G +DPYVK+ LLP   K +KL TK  +
Sbjct: 541 LGRIQFGLMYDFQNLTLTLRIIRAVDLPAKDVTGTSDPYVKILLLP--DKKHKLLTKVKK 368

Query: 440 NTRNPVWNETLQYHGITEEDMQRKTLRISVCDEDKFGHNEFIGETRFSLKKLKANQ 495
              NP WNE   + G     +  KTL + V D D+F  ++ IGET   L ++  +Q
Sbjct: 367 RNLNPHWNECFLFEGWPHNKLLEKTLYLQVIDYDRFSRDDPIGETYLPLNEIDLSQ 200

 Score = 65.5 bits (158), Expect = 6e-11,   Method: Compositional matrix adjust.
 Identities = 41/109 (37%), Positives = 55/109 (50%), Gaps = 1/109 (0%)
 Frame = -3

Query: 539 GKILVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGXXXXXXXXXXXX 598
           G+I   LMY  Q   L + IIR V L A D  G SDP+VK+ L PD              
Sbjct: 538 GRIQFGLMYDFQNLTLTLRIIRAVDLPAKDVTGTSDPYVKILLLPD--KKHKLLTKVKKR 365

Query: 599 TLNPEFNEEFFYD-IKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGIS 646
            LNP +NE F ++   H+ L +K+L + V DYD    +D IG   L ++
Sbjct: 364 NLNPHWNECFLFEGWPHNKLLEKTLYLQVIDYDRFSRDDPIGETYLPLN 218

 Score = 31.2 bits (69), Expect = 1.4,   Method: Compositional matrix adjust.
 Identities = 16/43 (37%), Positives = 22/43 (51%)
 Frame = -1

Query: 539 GKILVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWL 581
           G      + S   G L V +++   L A D  G SDP+VK+WL
Sbjct: 144 GSCCCPCVISPNIGRLTVIVMKAKELKAKDITGSSDPYVKIWL 16

 Score = 28.5 bits (62), Expect = 8.5,   Method: Compositional matrix adjust.
 Identities = 13/28 (46%), Positives = 18/28 (64%)
 Frame = -1

Query: 396 LQCTIIRAKGLKPMDSNGLADPYVKLHL 423
           L   +++AK LK  D  G +DPYVK+ L
Sbjct: 99  LTVIVMKAKELKAKDITGSSDPYVKIWL 16
>30040
          Length = 652

 Score = 73.2 bits (178), Expect = 4e-13,   Method: Composition-based stats.
 Identities = 39/133 (29%), Positives = 67/133 (50%)
 Frame = -3

Query: 541 ILVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGXXXXXXXXXXXXTL 600
           +L+SL Y      L V +++   L    ++  +DPFV++ L  +              ++
Sbjct: 650 VLISLSYLPAAERLTVVLMKAKDLKMSTSHPSADPFVRVSLLVEGKKVKRKKTSVRRASI 471

Query: 601 NPEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISAKGERLKHWYECLK 660
           NP +NE   +++    L K +L++SV D+D+    D +G C LG    G+ L HW E + 
Sbjct: 470 NPVWNEALAFNVPAEVLPKVTLEVSVLDHDLIGHGDVLGTCVLGAGCGGDELGHWNEMML 291

Query: 661 NKDKKIERWHQLQ 673
           ++ K I RWH L+
Sbjct: 290 HQRKTIARWHTLK 252

 Score = 63.5 bits (153), Expect = 3e-10,   Method: Composition-based stats.
 Identities = 35/97 (36%), Positives = 53/97 (54%)
 Frame = -3

Query: 386 SLLYDQDNSNLQCTIIRAKGLKPMDSNGLADPYVKLHLLPGASKSNKLRTKTLRNTRNPV 445
           SL Y      L   +++AK LK   S+  ADP+V++ LL    K  + +T   R + NPV
Sbjct: 641 SLSYLPAAERLTVVLMKAKDLKMSTSHPSADPFVRVSLLVEGKKVKRKKTSVRRASINPV 462

Query: 446 WNETLQYHGITEEDMQRKTLRISVCDEDKFGHNEFIG 482
           WNE L ++ +  E + + TL +SV D D  GH + +G
Sbjct: 461 WNEALAFN-VPAEVLPKVTLEVSVLDHDLIGHGDVLG 354
>31935
          Length = 554

 Score = 65.1 bits (157), Expect = 8e-11,   Method: Composition-based stats.
 Identities = 31/96 (32%), Positives = 55/96 (57%)
 Frame = -3

Query: 380 LGALEFSLLYDQDNSNLQCTIIRAKGLKPMDSNGLADPYVKLHLLPGASKSNKLRTKTLR 439
           LG ++ ++ Y      L  TI +   +   D + + DPYVKLHLLPG SK +K +T  ++
Sbjct: 540 LGRIQLTITYSAQRQKLDVTIHKIMNIPLRDPSSIPDPYVKLHLLPGRSKESKRKTSIIK 361

Query: 440 NTRNPVWNETLQYHGITEEDMQRKTLRISVCDEDKF 475
           +  NPV++ + +Y  I+  +++   L ++VC +  F
Sbjct: 360 DNCNPVYDASFEYL-ISISELRHTELEVTVCTQKGF 256

 Score = 42.7 bits (99), Expect = 5e-04,   Method: Composition-based stats.
 Identities = 25/88 (28%), Positives = 42/88 (47%)
 Frame = -3

Query: 539 GKILVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGXXXXXXXXXXXX 598
           G+I +++ YS Q+  L V I + +++   D +   DP+VKL L P               
Sbjct: 537 GRIQLTITYSAQRQKLDVTIHKIMNIPLRDPSSIPDPYVKLHLLPGRSKESKRKTSIIKD 358

Query: 599 TLNPEFNEEFFYDIKHSDLAKKSLDISV 626
             NP ++  F Y I  S+L    L+++V
Sbjct: 357 NCNPVYDASFEYLISISELRHTELEVTV 274
>16549
          Length = 607

 Score = 61.2 bits (147), Expect = 1e-09,   Method: Composition-based stats.
 Identities = 30/82 (36%), Positives = 48/82 (58%)
 Frame = +2

Query: 411 SNGLADPYVKLHLLPGASKSNKLRTKTLRNTRNPVWNETLQYHGITEEDMQRKTLRISVC 470
           S  L  PYVK +LLP   K  K +TK ++++ +P +NE LQY  + E + + +TL+++V 
Sbjct: 47  SAELPSPYVKTYLLPDPEKQTKRKTKIVKHSVHPTFNEVLQYR-MKETETRHRTLQVTVW 223

Query: 471 DEDKFGHNEFIGETRFSLKKLK 492
           D D    N F+G     L+ L+
Sbjct: 224 DHDMLKENNFLGAVYLRLRDLE 289

 Score = 50.1 bits (118), Expect = 3e-06,   Method: Composition-based stats.
 Identities = 21/69 (30%), Positives = 38/69 (55%)
 Frame = +2

Query: 575 PFVKLWLKPDMGXXXXXXXXXXXXTLNPEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKS 634
           P+VK +L PD              +++P FNE   Y +K ++   ++L ++VWD+D+ K 
Sbjct: 65  PYVKTYLLPDPEKQTKRKTKIVKHSVHPTFNEVLQYRMKETETRHRTLQVTVWDHDMLKE 244

Query: 635 NDYIGGCQL 643
           N+++G   L
Sbjct: 245 NNFLGAVYL 271
>01494
          Length = 2122

 Score = 48.9 bits (115), Expect = 7e-06,   Method: Compositional matrix adjust.
 Identities = 32/102 (31%), Positives = 50/102 (49%), Gaps = 1/102 (0%)
 Frame = +1

Query: 396  LQCTIIRAKGLKPMDSNGLADPYVKLHLLPGASKSNKLRTKT-LRNTRNPVWNETLQYHG 454
            L  TI+ A+ L      G+A P+V++ +      + K +T T + N  NPVWNE   +  
Sbjct: 1165 LTLTIVGARHLVK-SGRGIASPFVEIEVTGXECDNQKFKTGTRVDNGLNPVWNENCVFDV 1341

Query: 455  ITEEDMQRKTLRISVCDEDKFGHNEFIGETRFSLKKLKANQR 496
            +  E      LR +V DED FG   F+G+  F +  ++   R
Sbjct: 1342 LCPE---MALLRFAVMDEDIFGDPNFLGQAXFPVPCIRPGYR 1458
>14539
          Length = 436

 Score = 47.0 bits (110), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 26/85 (30%), Positives = 45/85 (52%), Gaps = 1/85 (1%)
 Frame = +3

Query: 413 GLADPYVKLHLLPGASKSNKLRTKT-LRNTRNPVWNETLQYHGITEEDMQRKTLRISVCD 471
           G+A P++++ +      + K +T+T + N  NPVWN+   +  +  E      LR +V D
Sbjct: 72  GIASPFLEIEIAGIECDNQKFKTETRVDNGLNPVWNKNCVFDVLCPE---LALLRFAVMD 242

Query: 472 EDKFGHNEFIGETRFSLKKLKANQR 496
           ED FG   F+G+  F +  +K+  R
Sbjct: 243 EDTFGDPNFLGQGCFPVPCIKSGFR 317
>26525
          Length = 455

 Score = 46.6 bits (109), Expect = 4e-05,   Method: Composition-based stats.
 Identities = 27/64 (42%), Positives = 36/64 (56%), Gaps = 1/64 (1%)
 Frame = +1

Query: 406 LKPMD-SNGLADPYVKLHLLPGASKSNKLRTKTLRNTRNPVWNETLQYHGITEEDMQRKT 464
           L P D S G  DPYVKL LLP   K +K +T+ +R T NP ++ET  + G+    M   T
Sbjct: 4   LPPRDPSLGGCDPYVKLQLLP--EKKHKCKTRVVRKTLNPKYDETFTFFGVNANQMGSIT 177

Query: 465 LRIS 468
           L  +
Sbjct: 178 LHFA 189
>25445
          Length = 460

 Score = 36.6 bits (83), Expect = 0.036,   Method: Compositional matrix adjust.
 Identities = 21/44 (47%), Positives = 26/44 (59%)
 Frame = -3

Query: 406 LKPMDSNGLADPYVKLHLLPGASKSNKLRTKTLRNTRNPVWNET 449
           L PMD NGLADPY K+ L+P  S       KT RN  + V +E+
Sbjct: 152 LCPMDPNGLADPYTKVKLIPYDS------NKTNRNKDHQVLSES 39
>30757
          Length = 496

 Score = 35.4 bits (80), Expect = 0.087,   Method: Composition-based stats.
 Identities = 28/109 (25%), Positives = 46/109 (42%), Gaps = 5/109 (4%)
 Frame = -2

Query: 166 PMPIKKTKPQQPAGEPATQEQPTPESRHPARAPA-----RGDMEDRRPPGQKPGPDLTSA 220
           P+  +   PQ  A  P + + PTP+   P R+PA           + P G+ P   L ++
Sbjct: 429 PLLKRSLAPQSKAATPVSSKTPTPKKASPKRSPAGVGKSPSPAAKKSPKGKSPAV-LAAS 253

Query: 221 PGRGSHGPPTRRASEARMSTAARDSEGWDHAHGGGTGDTSRSPAGLRRA 269
           P      P +R +S A +  A + S G   +         +SP+  RR+
Sbjct: 252 PRSPKSAPSSRNSSPASVKKAGK-SPGRPASPTAAPSSAKKSPSLGRRS 109
>17357
          Length = 482

 Score = 34.3 bits (77), Expect = 0.15,   Method: Compositional matrix adjust.
 Identities = 14/45 (31%), Positives = 24/45 (53%)
 Frame = +2

Query: 628 DYDIGKSNDYIGGCQLGISAKGERLKHWYECLKNKDKKIERWHQL 672
           D+D    N+ +G  ++G+   G+   HW E +    K+I  WH+L
Sbjct: 2   DWDRMTKNEVVGRLEIGVKCGGQEANHWNEVINCPRKQIAEWHKL 136
>13896
          Length = 827

 Score = 33.9 bits (76), Expect = 0.25,   Method: Compositional matrix adjust.
 Identities = 19/55 (34%), Positives = 28/55 (50%)
 Frame = +2

Query: 394 SNLQCTIIRAKGLKPMDSNGLADPYVKLHLLPGASKSNKLRTKTLRNTRNPVWNE 448
           ++ Q T++RA+ L     +G  D YV + L        K +T T+RN  NP W E
Sbjct: 152 THAQFTVLRARNLISKGKSGNNDVYVTIQL-----GKEKYQTSTIRNAHNPEWFE 301
>26304
          Length = 1290

 Score = 33.5 bits (75), Expect = 0.32,   Method: Compositional matrix adjust.
 Identities = 33/134 (24%), Positives = 57/134 (42%), Gaps = 18/134 (13%)
 Frame = +3

Query: 416  DPYVKLHLLPGASKSNK------LRTKTLRNTRNPVW-NETLQYHGITEEDMQRKTLRIS 468
            DPYVKL ++P  S   K      LR+    +T NPVW NET        + ++ +     
Sbjct: 906  DPYVKLTVVPSKSYPEKPHHHRELRSSVCPSTTNPVWDNETFTLEAYVTDLVELEI---- 1073

Query: 469  VCDEDKFGH-----NEFIGETRFSLKKLKANQRKN-----FNICLERVIPMKR-AGTTGS 517
               +DKF       + F+G+   +++++     ++     F++ L R  P    +GT   
Sbjct: 1074 ---KDKFSKSRPTMSRFLGKVVIAVQRIMDKVLQDQGCSQFHMDLNRRNPSDSVSGTLKF 1244

Query: 518  ARGMALYEEEQVER 531
              GM +      +R
Sbjct: 1245 KSGMEMVLNAHADR 1286
>34631
          Length = 651

 Score = 30.0 bits (66), Expect = 2.8,   Method: Composition-based stats.
 Identities = 16/34 (47%), Positives = 20/34 (58%)
 Frame = +3

Query: 192 RHPARAPARGDMEDRRPPGQKPGPDLTSAPGRGS 225
           R P  A AR  +E+R   G  PGP  +S+P RGS
Sbjct: 390 RPPTDAGARSRVEERS--GVIPGPQYSSSPARGS 485
>14132
          Length = 422

 Score = 30.0 bits (66), Expect = 2.9,   Method: Composition-based stats.
 Identities = 22/74 (29%), Positives = 38/74 (51%), Gaps = 10/74 (13%)
 Frame = -2

Query: 405 GLKPMDSNGLADPYVKLHLLPGASKSNKLRTKTLRNTRNPVWNETLQYHGIT-------- 456
           GLKP+D   +   + K++++P  +K++ L     R  +  + NE  Q H I         
Sbjct: 259 GLKPLDVEFMKRLHDKVNIIPLVAKADTLTPDECREFKKTILNEIAQ-HKIKIYEFPDCD 83

Query: 457 -EEDMQ-RKTLRIS 468
            EE+M+ +K LR+S
Sbjct: 82  DEEEMKIQKRLRVS 41
>01053
          Length = 396

 Score = 28.5 bits (62), Expect = 8.6,   Method: Compositional matrix adjust.
 Identities = 15/47 (31%), Positives = 24/47 (51%)
 Frame = +1

Query: 134 VWLCKICLEQREVWKRSGAWFFKGFPKQVLPQPMPIKKTKPQQPAGE 180
           ++ C++  E RE+ KR+G W     P  V+ Q   +   +P  PA E
Sbjct: 163 LFHCEVISETREIDKRAGVWLGLSVPTLVMGQ---LTVKEPANPAQE 294
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|21312314|ref|NP_082483.1| dual specificity
phosphatase 3 (vaccinia virus phosphatase VH1-related) [Mus musculus]
         (185 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

06234                                                                  84   4e-17
20614                                                                  72   1e-13
17534                                                                  69   1e-12
06977                                                                  58   2e-09
20242                                                                  36   0.009
14057                                                                  33   0.073
25697                                                                  30   0.60 
13427                                                                  26   9.0  
>06234
          Length = 540

 Score = 83.6 bits (205), Expect = 4e-17,   Method: Compositional matrix adjust.
 Identities = 55/141 (39%), Positives = 75/141 (53%), Gaps = 1/141 (0%)
 Frame = -3

Query: 31  NEVVPRVYVGNASVAQDITQLQKLGITHVLNAAEGRSFMHVNTSASFYEDSGITYLGIKA 90
           +E+VP++Y+G  +   D   L K GITHVL      S M           +G  Y  + A
Sbjct: 529 DEIVPKLYLGGITGIFDPAVLHKKGITHVL------SLMDRPLPDELM--TGFKYEHVFA 374

Query: 91  NDTQEFNLSAYFERATDFIDQALAHKNGRVLVHCREGYSRSPTLVIAYLMMRQKMDVKSA 150
            D  + +L    E+   F++Q    + G VLVHC+ G SRS T+VIAY+M  Q ++  +A
Sbjct: 373 LDLYDHDLLQDLEKCLTFVEQG--RQQGSVLVHCQAGASRSATVVIAYVMRTQALNKDTA 200

Query: 151 LSTVRQNREI-GPNDGFLAQL 170
           L  VR  R I  PNDGFL QL
Sbjct: 199 LEFVRTRRSIVRPNDGFLQQL 137
>20614
          Length = 646

 Score = 72.0 bits (175), Expect = 1e-13,   Method: Compositional matrix adjust.
 Identities = 42/101 (41%), Positives = 56/101 (55%), Gaps = 1/101 (0%)
 Frame = -2

Query: 81  SGITYLGIKANDTQEFNLSAYFERATDFIDQALAHKNGRVLVHCREGYSRSPTLVIAYLM 140
           S   YL I  ND+   +LS +F  A  FID+ +  + GRVLVHC  G SRS T+ +AYL+
Sbjct: 453 SHFRYLHIPVNDSASEDLSQWFPVANQFIDE-VRQQGGRVLVHCHAGRSRSATICLAYLI 277

Query: 141 MRQKMDVKSALSTVRQNRE-IGPNDGFLAQLCQLNDRLAKE 180
             +   ++SA   VR  RE I PN  F+ QL     R+  E
Sbjct: 276 NTRHYTLESAFEHVRSRREVIDPNLNFMRQLQDYQHRVDXE 154
>17534
          Length = 419

 Score = 68.9 bits (167), Expect = 1e-12,   Method: Compositional matrix adjust.
 Identities = 46/130 (35%), Positives = 66/130 (50%)
 Frame = +3

Query: 31  NEVVPRVYVGNASVAQDITQLQKLGITHVLNAAEGRSFMHVNTSASFYEDSGITYLGIKA 90
           +E+VP++Y+G  +   D   L K GITHVL      S M           +G  Y  + A
Sbjct: 27  DEIVPKLYLGGITGIFDPAVLHKKGITHVL------SLMDRPLPDELM--TGFKYEHVFA 182

Query: 91  NDTQEFNLSAYFERATDFIDQALAHKNGRVLVHCREGYSRSPTLVIAYLMMRQKMDVKSA 150
            D  + +L    E+   F++Q    + G VLVHC+ G SRS T+VIAY+M    ++  +A
Sbjct: 183 LDLYDHDLLQDLEKCLTFVEQG--RQQGSVLVHCQAGASRSATVVIAYVMRTXALNKDTA 356

Query: 151 LSTVRQNREI 160
           L  VR  R I
Sbjct: 357 LEFVRTRRSI 386
>06977
          Length = 1144

 Score = 57.8 bits (138), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 32/87 (36%), Positives = 46/87 (52%)
 Frame = +3

Query: 32  EVVPRVYVGNASVAQDITQLQKLGITHVLNAAEGRSFMHVNTSASFYEDSGITYLGIKAN 91
           +V+P +Y+GNA  + D+ QL+K GI ++LN          N    F +D    YL I  N
Sbjct: 903 KVLPYLYLGNAKNSADLNQLKKNGIHYILNVTP-------NVPNLFEDDGDFKYLQIPIN 1061

Query: 92  DTQEFNLSAYFERATDFIDQALAHKNG 118
           D    NLS++F  A  FID+A   + G
Sbjct: 1062DHWSQNLSSFFPDAIAFIDEARHRQQG 1142
>20242
          Length = 580

 Score = 36.2 bits (82), Expect = 0.009,   Method: Compositional matrix adjust.
 Identities = 19/57 (33%), Positives = 30/57 (52%)
 Frame = -3

Query: 32  EVVPRVYVGNASVAQDITQLQKLGITHVLNAAEGRSFMHVNTSASFYEDSGITYLGI 88
           EV+P +Y+GNA  + D+ QL++ GI ++LN          N    F ++    YL I
Sbjct: 155 EVLPYLYLGNAKNSADLNQLKQNGIHYILNVTP-------NVPNMFEDNDDFKYLQI 6
>14057
          Length = 1377

 Score = 33.1 bits (74), Expect = 0.073,   Method: Compositional matrix adjust.
 Identities = 33/128 (25%), Positives = 51/128 (39%), Gaps = 10/128 (7%)
 Frame = +2

Query: 41  NASVAQDITQLQKLGITHVLNAAEGRSFMHVNTSASFYEDSGITYLGIKANDTQE----- 95
           ++++ + I +LQK G  HV+   +         S    + +GI  L  + +D        
Sbjct: 737 DSTIDKYIEELQKHGAKHVVRVCDP------TYSREVLQKAGIDVLDWQFDDGSPPPNEV 898

Query: 96  ----FNL-SAYFERATDFIDQALAHKNGRVLVHCREGYSRSPTLVIAYLMMRQKMDVKSA 150
               FNL  A F+                V VHC  G  R+P LV A  +M   M  + A
Sbjct: 899 VGNWFNLLKARFKEEPGCC----------VAVHCVAGLGRAPVLV-AIALMEAGMKYEDA 1045

Query: 151 LSTVRQNR 158
           +  +RQ R
Sbjct: 1046VELIRQKR 1069
>25697
          Length = 470

 Score = 30.0 bits (66), Expect = 0.60,   Method: Compositional matrix adjust.
 Identities = 18/51 (35%), Positives = 25/51 (49%)
 Frame = +1

Query: 120 VLVHCREGYSRSPTLVIAYLMMRQKMDVKSALSTVRQNREIGPNDGFLAQL 170
           V VHC  G  R+P LV A  +M   M  + A+  +R+ R    N   L+ L
Sbjct: 247 VAVHCVAGLGRAPVLV-AIALMEAGMKYEDAVELIRRKRRGAINSKQLSYL 396
>13427
          Length = 1075

 Score = 26.2 bits (56), Expect = 9.0,   Method: Compositional matrix adjust.
 Identities = 9/25 (36%), Positives = 14/25 (56%)
 Frame = -1

Query: 120 VLVHCREGYSRSPTLVIAYLMMRQK 144
           VLV C   Y + P L + YL+ + +
Sbjct: 286 VLVQCEHAYIKQPLLAVQYLLSKHR 212
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|38371755|ref|NP_081269.1| dimethylarginine
dimethylaminohydrolase 1 [Mus musculus]
         (285 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

11730                                                                  85   4e-17
26117                                                                  28   2.9  
38516                                                                  27   8.0  
>11730
          Length = 1441

 Score = 84.7 bits (208), Expect = 4e-17,   Method: Compositional matrix adjust.
 Identities = 47/114 (41%), Positives = 68/114 (59%), Gaps = 1/114 (0%)
 Frame = +1

Query: 38  VDFARAERQHELYVGVLGSKLGLQVVQLPADESLPDCVFVEDVAVVCEETALITRPGAPS 97
           +D  +A  ++E+   VL     + +++L  DE+ PDC FVED AVV    AL+TRPG  S
Sbjct: 1   LDVEKACEEYEVIKDVL-KNCEVNLIELEEDENYPDCCFVEDCAVVIGGVALVTRPGHAS 177

Query: 98  RRKEVDMMKEALEK-LQLNIVEMKDENATLDGGDVLFTGREFFVGLSKRTNQRG 150
           R+ EV  ++  L++ L+L + E++D  ATLDGGDVLFTG+E            G
Sbjct: 178 RQGEVGEIRRVLKQDLRLVVQEVRDAKATLDGGDVLFTGKEILWAWGSEPTSSG 339

 Score = 58.2 bits (139), Expect = 4e-09,   Method: Compositional matrix adjust.
 Identities = 43/130 (33%), Positives = 67/130 (51%), Gaps = 2/130 (1%)
 Frame = +3

Query: 139 FVGLSKRTNQRGAEILADTFKDYAVSTVPV--ADSLHLKSFCSMAGPNLIAIGSSESAQK 196
           FVG+ KRTN  GA+ +AD F DY+VS + +  +D  HLK   SMAG  ++A+        
Sbjct: 303 FVGVGKRTNFLGAKAVADAFCDYSVSLLDISASDLGHLKDGFSMAGREIMAVAPGTDCAV 482

Query: 197 ALKIMQQMSDHRYDKLTVPDDMAANCIYLNIPSKGHVLLHRTPEEYPESAKVYEKLKDHL 256
            LK MQ+++  +Y  + +    A + +Y+N    G ++ H   E    S   Y KL +  
Sbjct: 483 LLKKMQEVASCQYKVMQLDSRRAVDMMYIN----GRLIHHVRSEMGDHS---YGKLDEK- 638

Query: 257 LIPVSNSEME 266
            IP +   +E
Sbjct: 639 -IPYTRHHIE 665
>26117
          Length = 792

 Score = 28.5 bits (62), Expect = 2.9,   Method: Compositional matrix adjust.
 Identities = 14/42 (33%), Positives = 25/42 (59%)
 Frame = +1

Query: 201 MQQMSDHRYDKLTVPDDMAANCIYLNIPSKGHVLLHRTPEEY 242
           + Q+ D ++  L V  D+   C+YL++ S   VL  RTP+++
Sbjct: 469 LPQIIDRQFALLFVFADIL--CLYLHLKSAAFVLTMRTPDKF 588
>38516
          Length = 642

 Score = 27.3 bits (59), Expect = 8.0,   Method: Compositional matrix adjust.
 Identities = 11/32 (34%), Positives = 18/32 (56%)
 Frame = +2

Query: 197 ALKIMQQMSDHRYDKLTVPDDMAANCIYLNIP 228
            L  +  +  HR+D LT  +   ANC+ L++P
Sbjct: 398 VLNWLLFLCYHRHDXLTTHNSKYANCLCLSLP 493
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6679078|ref|NP_032731.1| nucleoside-diphosphate
kinase 2 [Mus musculus]
         (152 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

32935                                                                  83   4e-17
02656                                                                  81   1e-16
02733                                                                  69   1e-12
14087                                                                  29   0.89 
31902                                                                  28   1.1  
05501                                                                  28   2.1  
>32935
          Length = 1188

 Score = 83.2 bits (204), Expect = 4e-17,   Method: Compositional matrix adjust.
 Identities = 45/133 (33%), Positives = 73/133 (54%), Gaps = 3/133 (2%)
 Frame = +2

Query: 5   ERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLVAMKFLRASEEHLKQHYIDLKDRPFFPGL 64
           ERT   IKPD V++  +G+++ +  QKGF +  ++  +       + Y + + +PF   L
Sbjct: 278 ERTLGLIKPDAVEK--LGQVLDKILQKGFLISRLRMCKLDRNTALEFYQEHRSKPFLNAL 451

Query: 65  VKYMNSGPVVAMVWEGLNVVKTGRVMLGETNPADSK---PGTIRGDFCIQVGRNIIHGSD 121
           + Y+ SGPVVA    G N V   R  +G T+P+ ++   P +IR  +   V  N +HGSD
Sbjct: 452 LDYVTSGPVVAFEIVGENAVGAWREAIGPTDPSLARKEAPTSIRAQYGTDVTCNAVHGSD 631

Query: 122 SVESAEKEIHLWF 134
           S  SA +E+  +F
Sbjct: 632 SPGSAAREVEFFF 670

 Score = 44.7 bits (104), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 34/141 (24%), Positives = 63/141 (44%), Gaps = 12/141 (8%)
 Frame = +1

Query: 7   TFIAIKPDGVQRGLVGEIIKRFEQKGFRLVAMKFL---RASEEHLKQHYIDLKDRPFFPG 63
           T   IKP   + G+ G+II    + GFR+ + +     +A+ E   + Y  +     +P 
Sbjct: 718 TCCIIKPSAFKAGVAGKIINAITEAGFRVGSAEMFTLEKANAEEFLEVYKGVVHE--YPA 891

Query: 64  LVKYMNSGPVVAMVWEGLN------VVKTGRVMLGETNPADS---KPGTIRGDFCIQVGR 114
           +V  + SGP +A+   G +      +    R + G  +P  +   +P T+R  F     +
Sbjct: 892 MVTELTSGPCLALEIVGGSGTNASLLAPAFRELAGPVDPEIARHLRPRTLRAMFGTDKIK 1071

Query: 115 NIIHGSDSVESAEKEIHLWFK 135
           N +H +D  +    E+  +FK
Sbjct: 1072NAVHCTDLPDDGPLEVEYFFK 1134
>02656
          Length = 2642

 Score = 81.3 bits (199), Expect = 1e-16,   Method: Compositional matrix adjust.
 Identities = 47/134 (35%), Positives = 71/134 (52%), Gaps = 3/134 (2%)
 Frame = +3

Query: 4    LERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLVAMKFLRASEEHLKQHYIDLKDRPFFPG 63
            +E+T   IKPDG   G    II++  Q GFR+ A K    + +  +  Y D KD+ ++  
Sbjct: 1071 VEQTVAMIKPDGY--GTKDAIIEKIHQAGFRIAARKETTITRDIAESFYDDQKDKDYYES 1244

Query: 64   LVKYMNSGPVVAMVWEGLNVVKTGRVMLGETNPADSK---PGTIRGDFCIQVGRNIIHGS 120
            LV++M SGP + MV      V   R  +G T+P  +K   P ++R  F   V +N +HG+
Sbjct: 1245 LVEHMTSGPTMFMVLSREGAVDGWREEIGPTDPTKAKEQNPNSLRAQFGTDVLQNAVHGA 1424

Query: 121  DSVESAEKEIHLWF 134
             S E A+K+I   F
Sbjct: 1425 SSSEEAKKKIKAVF 1466

 Score = 70.9 bits (172), Expect = 2e-13,   Method: Compositional matrix adjust.
 Identities = 40/141 (28%), Positives = 77/141 (54%), Gaps = 4/141 (2%)
 Frame = +3

Query: 4   LERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLVAMKFLRASEEHLKQHYIDLKDRPFFPG 63
           ++RT   I+PD         I+++ ++ GF++   K +  ++E  ++ Y +   +P++  
Sbjct: 666 VQRTLALIRPDAFANNKDA-ILEKIKEAGFQIALHKEVSLTKEQAEEFYKEHAGQPYYDE 842

Query: 64  LVKYMNSGPVVAMVWEGLNVVKTGRVMLGETNPADSK---PGTIRGDFCI-QVGRNIIHG 119
           L   M+SGP++A+     + V+  R MLG T+  ++K   P  +R  F +     N +HG
Sbjct: 843 LTDRMSSGPLLALGLAREDAVENWREMLGPTDVEEAKTAAPDCLRAQFAVDSTAINQLHG 1022

Query: 120 SDSVESAEKEIHLWFKPEELI 140
           SDS +SA+KE+  +F  E+ +
Sbjct: 1023SDSTQSAKKELEFFFPVEQTV 1085

 Score = 65.9 bits (159), Expect = 7e-12,   Method: Compositional matrix adjust.
 Identities = 44/135 (32%), Positives = 69/135 (51%), Gaps = 7/135 (5%)
 Frame = +3

Query: 7   TFIAIKPDGVQRGLVGEIIKRFEQKGFRLVAMKFLRASEEHLKQHYIDLKDRPFFPGLVK 66
           T   IKP+ V  G V EI+   + +G  + A +  + +E+  ++ Y  L+   +F  LV 
Sbjct: 219 TVAIIKPNVVANGKVDEILAEMKARGINVKAQEERQLTEDEAREFYSHLQGEEYFEDLVA 398

Query: 67  YMNSGPVVAMV----WEGLNVVKTGRVMLGETNPADSK---PGTIRGDFCIQVGRNIIHG 119
           +M SGP   +V     E  +VVK  R MLG     D+K   P ++R  +      N +HG
Sbjct: 399 FMASGPSHVLVLTEGQEDDSVVKDWRDMLGPPTVEDAKEQAPESLRARYGQGGLMNAVHG 578

Query: 120 SDSVESAEKEIHLWF 134
           SDS E+A +E+  +F
Sbjct: 579 SDSKETAARELAFFF 623
>02733
          Length = 853

 Score = 68.6 bits (166), Expect = 1e-12,   Method: Compositional matrix adjust.
 Identities = 37/112 (33%), Positives = 59/112 (52%), Gaps = 3/112 (2%)
 Frame = -1

Query: 26  KRFEQKGFRLVAMKFLRASEEHLKQHYIDLKDRPFFPGLVKYMNSGPVVAMVWEGLNVVK 85
           ++  Q GFR+ A K    + +  +  Y D KD+ ++  LV++M SGP + MV      V 
Sbjct: 748 RKIHQAGFRIAARKETTITRDIAESFYDDQKDKDYYESLVEHMTSGPTMFMVLSREGAVD 569

Query: 86  TGRVMLGETNPADSK---PGTIRGDFCIQVGRNIIHGSDSVESAEKEIHLWF 134
             R  +G T+P  +K   P ++R  F   V +N +HG+ S E A+K+I   F
Sbjct: 568 GWREEIGPTDPTKAKEQNPNSLRAQFGTDVLQNAVHGASSSEEAKKKIKAVF 413
>14087
          Length = 2025

 Score = 28.9 bits (63), Expect = 0.89,   Method: Compositional matrix adjust.
 Identities = 14/41 (34%), Positives = 22/41 (53%)
 Frame = +2

Query: 60  FFPGLVKYMNSGPVVAMVWEGLNVVKTGRVMLGETNPADSK 100
           ++  LV++M SGP + MV      V   R  +G T+P  S+
Sbjct: 2   YYESLVEHMTSGPTMFMVLSREGAVDGWREEIGPTDPTKSQ 124
>31902
          Length = 546

 Score = 28.5 bits (62), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 14/38 (36%), Positives = 22/38 (57%), Gaps = 3/38 (7%)
 Frame = +1

Query: 88  RVMLGETNPADSK---PGTIRGDFCIQVGRNIIHGSDS 122
           R  +G T+P+ ++   P +IR  +   V  N +HGSDS
Sbjct: 391 REAIGPTDPSLARKEAPTSIRAQYGTDVTCNAVHGSDS 504
>05501
          Length = 1740

 Score = 27.7 bits (60), Expect = 2.1,   Method: Compositional matrix adjust.
 Identities = 13/55 (23%), Positives = 27/55 (49%), Gaps = 12/55 (21%)
 Frame = -1

Query: 109  CIQVGRNIIHGSDSVESA------------EKEIHLWFKPEELIDYKSCAHDWVY 151
            C+ + ++++HG  S E +             + +++ FK EE +DY   A +W +
Sbjct: 1725 CMVMSKSMLHGKISYEDSFAQIMRLQPFDLRRRLYIIFKGEEGLDYGGVAREWFF 1561
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|7304993|ref|NP_038838.1| drebrin-like isoform 2 [Mus
musculus]
         (433 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

16716                                                                  86   4e-17
15115                                                                  81   6e-16
28095                                                                  54   2e-07
17286                                                                  52   6e-07
01494                                                                  51   9e-07
12324                                                                  51   1e-06
29687                                                                  49   3e-06
31183                                                                  46   3e-05
20131                                                                  36   0.034
13664                                                                  32   0.70 
29636                                                                  31   0.98 
19661                                                                  31   1.1  
19334                                                                  31   1.2  
29243                                                                  30   1.9  
30899                                                                  29   4.8  
>16716
          Length = 934

 Score = 85.5 bits (210), Expect = 4e-17,   Method: Compositional matrix adjust.
 Identities = 39/63 (61%), Positives = 48/63 (76%)
 Frame = -1

Query: 369 SQGFSGQGLCARALYDYQAADDTEISFDPENLITGIEVIDEGWWRGYGPDGHFGMFPANY 428
           +Q   G G  A ALYDYQAADD E++FDP+++IT IE+ID+GWWRG    G  G+FPANY
Sbjct: 493 AQSQPGGGSTAIALYDYQAADDDELTFDPDDVITDIEMIDDGWWRG-SCHGKNGLFPANY 317

Query: 429 VEL 431
           VEL
Sbjct: 316 VEL 308
>15115
          Length = 443

 Score = 81.3 bits (199), Expect = 6e-16,   Method: Compositional matrix adjust.
 Identities = 33/48 (68%), Positives = 43/48 (89%)
 Frame = -2

Query: 385 YQAADDTEISFDPENLITGIEVIDEGWWRGYGPDGHFGMFPANYVELI 432
           +QA DDTEI+FDP+++IT I+ IDEGWW+G+ PDG +GMFPANYVEL+
Sbjct: 433 HQAGDDTEITFDPDDIITNIDQIDEGWWQGFAPDGSYGMFPANYVELL 290
>28095
          Length = 597

 Score = 53.5 bits (127), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 26/59 (44%), Positives = 37/59 (62%), Gaps = 1/59 (1%)
 Frame = +3

Query: 375 QGLCARALYDYQAADDTEISFDPENLITGIEVIDEGWWRG-YGPDGHFGMFPANYVELI 432
           +G+  +A+YDYQAAD  E+SF+  + I   + +D GW  G     G +GM P+NYVE I
Sbjct: 252 RGMVCKAMYDYQAADSDEVSFNDGDTIIECQPVDAGWMTGRVERTGQYGMLPSNYVERI 428
>17286
          Length = 489

 Score = 51.6 bits (122), Expect = 6e-07,   Method: Compositional matrix adjust.
 Identities = 24/55 (43%), Positives = 33/55 (60%)
 Frame = +3

Query: 378 CARALYDYQAADDTEISFDPENLITGIEVIDEGWWRGYGPDGHFGMFPANYVELI 432
           CARA+YD+    D E+ F   ++IT I  +DE W+ G    G  G FP NYVE++
Sbjct: 27  CARAIYDFLPESDGELGFQEGDMITLISQVDENWFEG-SVHGKVGYFPINYVEVV 188
>01494
          Length = 2122

 Score = 51.2 bits (121), Expect = 9e-07,   Method: Compositional matrix adjust.
 Identities = 30/71 (42%), Positives = 40/71 (56%), Gaps = 1/71 (1%)
 Frame = +3

Query: 364 DNYMQSQGFSGQGLCARALYDYQAADDTEISFDPENLITGIEVIDEGWWRG-YGPDGHFG 422
           D Y+    F+ + L  +AL+DY A  D E+SF    +IT +   D GWWRG YG      
Sbjct: 270 DVYINPNDFTTK-LRVKALHDYNANRDDELSFCKGAIITNVSRQDGGWWRGDYGAKKQH- 443

Query: 423 MFPANYVELIE 433
            FP+N+VE IE
Sbjct: 444 WFPSNFVEEIE 476
>12324
          Length = 946

 Score = 50.8 bits (120), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 24/50 (48%), Positives = 33/50 (66%)
 Frame = +3

Query: 381 ALYDYQAADDTEISFDPENLITGIEVIDEGWWRGYGPDGHFGMFPANYVE 430
           A+YDY+A  D E++F   ++I  I   D+GWW G   DG  G+FP+NYVE
Sbjct: 702 AIYDYEAEKDDELTFSENSVIYVIRKNDDGWWEGVM-DGVTGLFPSNYVE 848
>29687
          Length = 434

 Score = 49.3 bits (116), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 29/72 (40%), Positives = 41/72 (56%), Gaps = 1/72 (1%)
 Frame = -2

Query: 363 IDNYMQSQGFSGQGLCARALYDYQAADDTEISFDPENLITGIEVIDEGWWRG-YGPDGHF 421
           +D Y+    F+ + L  +AL+DY A  + E+SF    +IT +   D GWWRG YG     
Sbjct: 337 VDLYINPNDFTTK-LRVKALHDYNAKREDELSFCKGAIITNVSRQDGGWWRGDYGTKKQH 161

Query: 422 GMFPANYVELIE 433
             FP+NYVE I+
Sbjct: 160 -WFPSNYVEEID 128
>31183
          Length = 923

 Score = 45.8 bits (107), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 21/34 (61%), Positives = 27/34 (79%)
 Frame = +1

Query: 398 ENLITGIEVIDEGWWRGYGPDGHFGMFPANYVEL 431
           +++IT IE+ID+GWWRG    G  G+FPANYVEL
Sbjct: 1   DDVITDIEMIDDGWWRG-SCHGKNGLFPANYVEL 99
>20131
          Length = 574

 Score = 35.8 bits (81), Expect = 0.034,   Method: Compositional matrix adjust.
 Identities = 19/57 (33%), Positives = 27/57 (47%), Gaps = 4/57 (7%)
 Frame = -2

Query: 378 CARALYDYQAADDTEISFDPENLITGIEVIDEGWWRG----YGPDGHFGMFPANYVE 430
            A  +  Y A  + ++S +P NLI   +    GWW G     G     G FPA+YV+
Sbjct: 279 IAMVIAPYTATGNGQLSLEPGNLIHVRQKSPRGWWEGELQARGQRKKIGWFPADYVK 109
>13664
          Length = 507

 Score = 31.6 bits (70), Expect = 0.70,   Method: Compositional matrix adjust.
 Identities = 15/43 (34%), Positives = 21/43 (48%)
 Frame = +2

Query: 381 ALYDYQAADDTEISFDPENLITGIEVIDEGWWRGYGPDGHFGM 423
           ALYDY+A    E++    ++I  +    E WW G   DG  G 
Sbjct: 377 ALYDYKAQRSDELTILSGDVIMLLHKDSESWWMGELLDGQQGF 505
>29636
          Length = 354

 Score = 30.8 bits (68), Expect = 0.98,   Method: Composition-based stats.
 Identities = 18/58 (31%), Positives = 29/58 (50%), Gaps = 11/58 (18%)
 Frame = +1

Query: 380 RALYDYQAADDTEI-------SFDPENLITGIEVIDEGWWRGY--GPDGHF--GMFPA 426
           RAL++Y   DD  I       SF   +++  I++ D  WW+ +  G D H   G+ P+
Sbjct: 79  RALFNYDPEDDPYIPCRELGISFLKGDILHAIQLSDSNWWQAHREGEDAHMLAGLIPS 252
>19661
          Length = 684

 Score = 30.8 bits (68), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 14/48 (29%), Positives = 26/48 (54%)
 Frame = +1

Query: 128 IMEKVAKASGANYSFHKESTSFQDVGPQAPVGSVYQKTNAISEIKRVG 175
           ++ + +  S A+Y+    +   QDV   +PV    + T+ +SE+ RVG
Sbjct: 88  LVLRASDVSSASYADMHLTVILQDVNDNSPVFESLRYTHTVSEVARVG 231
>19334
          Length = 923

 Score = 30.8 bits (68), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 14/48 (29%), Positives = 26/48 (54%)
 Frame = +2

Query: 128 IMEKVAKASGANYSFHKESTSFQDVGPQAPVGSVYQKTNAISEIKRVG 175
           ++ + +  S A+Y+    +   QDV   +PV    + T+ +SE+ RVG
Sbjct: 737 LVLRASDVSSASYADMHLTVILQDVNDNSPVFESLRYTHTVSEVARVG 880
>29243
          Length = 1147

 Score = 30.0 bits (66), Expect = 1.9,   Method: Compositional matrix adjust.
 Identities = 18/55 (32%), Positives = 27/55 (49%), Gaps = 3/55 (5%)
 Frame = +2

Query: 379 ARALYDYQAADDTEISFDPENLITGIEVI--DEGWWRGYGPDGH-FGMFPANYVE 430
           A A+YDY A   +++S    + I  +     D+GWW+G        G FP  YV+
Sbjct: 638 AVAVYDYAATSTSQLSMKLNDRIAILSKNGQDKGWWKGENLRTQKIGYFPLAYVD 802
>30899
          Length = 698

 Score = 28.9 bits (63), Expect = 4.8,   Method: Compositional matrix adjust.
 Identities = 10/16 (62%), Positives = 15/16 (93%)
 Frame = -2

Query: 380 RALYDYQAADDTEISF 395
           RALYD++AA+D E++F
Sbjct: 55  RALYDFEAAEDNELTF 8
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|20270297|ref|NP_620097.1| trimethyllysine
hydroxylase, epsilon [Mus musculus]
         (421 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

19899                                                                  85   5e-17
17907                                                                  77   1e-14
28693                                                                  38   0.006
11233                                                                  30   1.2  
04817                                                                  30   1.7  
07764                                                                  30   1.9  
03717                                                                  28   9.1  
>19899
          Length = 944

 Score = 85.1 bits (209), Expect = 5e-17,   Method: Compositional matrix adjust.
 Identities = 76/269 (28%), Positives = 117/269 (43%), Gaps = 8/269 (2%)
 Frame = -1

Query: 23  AQGLHLSNFKSLFSSSIHWCHTTSKSVNCTWHQHEDHLELQYAGTVMRFDYVWLRDHCRS 82
           AQG  L NF+          + T K +  TW            G V  F  +WLR  C  
Sbjct: 734 AQG-QLDNFE---------LNNTGKLLTVTWED----------GQVSNFHSLWLRYSCHC 615

Query: 83  ASCYNSKTHQR-----SLDTASVDLCIKPKTVHLDETMLFFTWPDGHVTRYDLDWLVKNS 137
            +C    T QR      LD A+V   ++      D  ++ F   + H     +++L +  
Sbjct: 614 KNCLEEHTGQRLYLCEDLDPAAV---LESVERDGDNLVVQFAGKERHRGYVPINFLQEYD 444

Query: 138 YEGQKQKVIQPRILWNSKLYQQAQVPSVDFQCFLETNEGLKKFLQNFLLYGIAFVENVPP 197
           Y        +  I  N  +Y + ++P V +Q   E  EGL  +++N   YG   ++ VP 
Sbjct: 443 YSKAALMKKKAAIDVN--IYAK-KIPEVSYQDLTEKEEGLYWWVKNLSDYGFCVIKGVPT 273

Query: 198 TEEHTEKLAERISLIRETIYGRMW-YFTSDFSRGDTAYTKLALDRHTDTTYFQEPCGIQV 256
            E    K+AE I  I++TIY  ++    SD    + AY+   L  H D  Y++ P G+Q 
Sbjct: 272 EEFMVLKMAEMIGPIQDTIYDDVFDVHVSDHQLTNVAYSADGLIYHQDLLYYESPPGLQF 93

Query: 257 FHCLKHEG--TGGRTLLVDGFYAAQQVLQ 283
            H LK++    GG +L+VD F  A +  Q
Sbjct: 92  LHTLKYDDCVMGGESLIVDMFKVAAEFRQ 6
>17907
          Length = 540

 Score = 77.4 bits (189), Expect = 1e-14,   Method: Compositional matrix adjust.
 Identities = 43/142 (30%), Positives = 74/142 (52%), Gaps = 3/142 (2%)
 Frame = +2

Query: 162 VPSVDFQCFLETNEGLKKFLQNFLLYGIAFVENVPPTEEHTEKLAERIS-LIRETIYGRM 220
           +P V ++  + +  G+ K+++     G+  V+ VP  E   +K+  R++   + TIYG  
Sbjct: 50  IPRVSYEDVMASKAGVYKWVKALSETGLTIVDGVPCEEGMVKKVCTRVADYPQHTIYGET 229

Query: 221 WYFTSDFSRGDTAYTKLALDRHTDTTYFQEPCGIQVFHCLK--HEGTGGRTLLVDGFYAA 278
           +   +     + AY+   L  H D   ++ P GIQ  HC++   E TGG +  VD F  A
Sbjct: 230 FDVVASDQPLNAAYSAGDLKLHMDLCMYEAPPGIQALHCIQFDKEITGGDSFFVDLFQVA 409

Query: 279 QQVLQKAPEEFELLSKVPLKHE 300
           +   +K P++F+LL KVP+  E
Sbjct: 410 ETFREKFPQDFDLLCKVPITLE 475
>28693
          Length = 703

 Score = 38.1 bits (87), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 21/68 (30%), Positives = 35/68 (51%), Gaps = 3/68 (4%)
 Frame = -1

Query: 353 YTAHRTLTTELRRPENELWVKLKPGKVLFIDNWRVLHGRESF---TGYRQLCGCYLTRDD 409
           Y A +     +    N  W +L+PG+++  +N RVLH R +F    G R L GCY+   +
Sbjct: 607 YQAVKKFYVLINNYPNMFWHRLQPGEMVAFNNRRVLHARTAFDSNGGQRFLQGCYIEMSE 428

Query: 410 VLNTARLL 417
             +  ++L
Sbjct: 427 FRSCVQVL 404
>11233
          Length = 1312

 Score = 30.4 bits (67), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 14/37 (37%), Positives = 22/37 (59%)
 Frame = -3

Query: 287 EEFELLSKVPLKHEYIENVGQCHNHMIGVGPILNIYP 323
           +E+ELL  +      +  VG  H+H+IG   +LNI+P
Sbjct: 914 QEYELLKHLKKSTLLVMFVGSSHDHIIGSFVVLNIFP 804
>04817
          Length = 519

 Score = 30.0 bits (66), Expect = 1.7,   Method: Compositional matrix adjust.
 Identities = 11/37 (29%), Positives = 20/37 (54%)
 Frame = +3

Query: 216 IYGRMWYFTSDFSRGDTAYTKLALDRHTDTTYFQEPC 252
           IYG +WY+ +  + G +    L +   +D  +F+ PC
Sbjct: 279 IYGHIWYWITP*NGGGSQVYVLVIQSVSDCGWFRNPC 389
>07764
          Length = 543

 Score = 30.0 bits (66), Expect = 1.9,   Method: Compositional matrix adjust.
 Identities = 18/60 (30%), Positives = 28/60 (46%)
 Frame = +2

Query: 156 LYQQAQVPSVDFQCFLETNEGLKKFLQNFLLYGIAFVENVPPTEEHTEKLAERISLIRET 215
           L QQA   S+ + C  + +   K+ +QN     I F E V  T E T  L+   +  ++T
Sbjct: 239 LSQQAPTHSISWPCLNQLDSKTKRVMQNSQSQCIVFTEIVESTRESTSVLSSMAAPSKKT 418
>03717
          Length = 1705

 Score = 27.7 bits (60), Expect = 9.1,   Method: Compositional matrix adjust.
 Identities = 16/49 (32%), Positives = 25/49 (51%)
 Frame = -1

Query: 291 LLSKVPLKHEYIENVGQCHNHMIGVGPILNIYPWNKELYLIRYNNYDRA 339
           LL ++P K EY+  V  C+N  +G   I ++YP     Y+    N+ R 
Sbjct: 529 LLHRLPTK-EYLHTVEVCYNESLGTFKIDSLYPEYXLSYMSVITNFSRP 386
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6680924|ref|NP_031713.1| cofilin 1, non-muscle [Mus
musculus]
         (166 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

16094                                                                  83   5e-17
20812                                                                  27   3.9  
>16094
          Length = 1173

 Score = 83.2 bits (204), Expect = 5e-17,   Method: Compositional matrix adjust.
 Identities = 52/149 (34%), Positives = 79/149 (53%), Gaps = 6/149 (4%)
 Frame = +2

Query: 1   MASGVAVSDGVIKVFNDMKVRKSSTPEEVKKRKKAVLFCLSEDKKNIILE------EGKE 54
           M+SG+ VSD V +V+  +K+   +       +++  LF L++DK  I+L+      E K 
Sbjct: 125 MSSGIQVSDEVKQVYEQVKMNGPN-------KRQFALFKLNDDKTEIVLDYMADKCESKS 283

Query: 55  ILVGDVGQTVDDPYTTFVKMLPDKDCRYALYDATYETKESKKEDLVFIFWAPENAPLKSK 114
               + GQ     +   +  LP KD RY L+D  YE K      LV I W PE   +  K
Sbjct: 284 NETKEKGQA--KHFQEVINTLPKKDGRYLLFDYEYEGKHGPASKLVLIMWCPEILSVNMK 457

Query: 115 MIYASSKDAIKKKLTGIKHELQANCYEEV 143
           M+YASSKDA+KK    I  ++QA+C +++
Sbjct: 458 MLYASSKDALKKTCKDIGADIQADCLDDL 544
>20812
          Length = 424

 Score = 26.9 bits (58), Expect = 3.9,   Method: Compositional matrix adjust.
 Identities = 22/67 (32%), Positives = 32/67 (47%), Gaps = 1/67 (1%)
 Frame = -3

Query: 99  LVFIFWAPENAPLKSKMIYASSKDAI-KKKLTGIKHELQANCYEEVKDRCTLAEKLGGSA 157
           L+FI W+  N PL     Y     +I K +L  I +E+    YE  KD+ TL  +   S 
Sbjct: 287 LIFILWSLWNRPLMKLKFYEHR*ISIYKTELVCILYEI----YETEKDKHTL*IRRN*SC 120

Query: 158 VISLEGK 164
           + + E K
Sbjct: 119 IHTYETK 99
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|225735645|ref|NP_035309.3| prosaposin isoform B
preproprotein [Mus musculus]
         (557 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

31874                                                                  86   6e-17
04994                                                                  68   1e-11
01365                                                                  51   1e-06
06528                                                                  45   1e-04
09010                                                                  30   2.9  
11272                                                                  29   5.9  
07739                                                                  28   9.2  
>31874
          Length = 460

 Score = 85.5 bits (210), Expect = 6e-17,   Method: Compositional matrix adjust.
 Identities = 52/172 (30%), Positives = 90/172 (52%), Gaps = 4/172 (2%)
 Frame = -1

Query: 348 CALLPDPARTKCQEVVGTFGPSLLDIFIHEVNPSSLCGVIGLCAARPELVEALEQPAPAI 407
           C+ LP    T+C+  V  +GP + ++ + E++P ++C  +GLC A        +  APA+
Sbjct: 457 CSYLPANLSTECKSYVSQYGPLVFEVLVAELDPDTICQTLGLCNAT-------KTQAPAL 299

Query: 408 VSALLXXXXXXXXXXXXXXXXXXXHVPP----QKNGGFCEVCKKLVLYLEHNLEKNSTKE 463
               +                   H+ P    +KNG  C +C+ +V  LE  + +N+T++
Sbjct: 298 THVXVGSSLGTV------------HILPADHKEKNGASCSMCQLIVGELESLIPENATEQ 155

Query: 464 EILAALEKGCSFLPDPYQKQCDDFVAEYEPLLLEILVEVMDPGFVCSKIGVC 515
           E+ AAL+K C  +PD  +K+CD FV +Y P+L+++L+       VC  +GVC
Sbjct: 154 EVEAALDKVCDEVPDILKKECDTFVTQYTPVLVKLLLNGALKE-VCVVLGVC 2

 Score = 62.0 bits (149), Expect = 6e-10,   Method: Compositional matrix adjust.
 Identities = 49/165 (29%), Positives = 76/165 (46%), Gaps = 3/165 (1%)
 Frame = -1

Query: 229 CDRLGPGVSDICKNYVDQYSEVCVQMLMHMQDQQPKEICVLAGFCNEVK-RVPMKTLVPA 287
           C  L   +S  CK+YV QY  +  ++L+   D  P  IC   G CN  K + P  T V  
Sbjct: 457 CSYLPANLSTECKSYVSQYGPLVFEVLVAELD--PDTICQTLGLCNATKTQAPALTHVXV 284

Query: 288 TETIK--NILPALEMMDPYEQNLVQAHNVILCQTCQFVMNKFSELIVNNATEELLVKGLS 345
             ++   +ILPA    D  E+N         C  CQ ++ +   LI  NATE+ +   L 
Sbjct: 283 GSSLGTVHILPA----DHKEKNGAS------CSMCQLIVGELESLIPENATEQEVEAALD 134

Query: 346 NACALLPDPARTKCQEVVGTFGPSLLDIFIHEVNPSSLCGVIGLC 390
             C  +PD  + +C   V  + P L+ + ++      +C V+G+C
Sbjct: 133 KVCDEVPDILKKECDTFVTQYTPVLVKLLLNGA-LKEVCVVLGVC 2

 Score = 41.6 bits (96), Expect = 8e-04,   Method: Compositional matrix adjust.
 Identities = 25/77 (32%), Positives = 43/77 (55%), Gaps = 1/77 (1%)
 Frame = -1

Query: 63  CDICKTVVTEAGNLLKDNATQEEILHYLEKTCEWIHDSSLSASCKEVVDSYLPVILD-MI 121
           C +C+ +V E  +L+ +NAT++E+   L+K C+ + D  L   C   V  Y PV++  ++
Sbjct: 220 CSMCQLIVGELESLIPENATEQEVEAALDKVCDEVPD-ILKKECDTFVTQYTPVLVKLLL 44

Query: 122 KGEMSNPGEVCSALNLC 138
            G +    EVC  L +C
Sbjct: 43  NGALK---EVCVVLGVC 2
>04994
          Length = 969

 Score = 67.8 bits (164), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 35/117 (29%), Positives = 56/117 (47%), Gaps = 6/117 (5%)
 Frame = -1

Query: 441 FCEVCKKLVLYLEHNLEKNSTKEEILAALEKGCSFLPDPYQKQCDDFVAEYEPLLLEILV 500
            C +C+ L  Y    L   +T+ +I   LE  C+ LP+     C   V ++ P +L+ L 
Sbjct: 966 MCIICQTLANYAAEGLSDPATESQIEKLLEDACTVLPENRVSDCKAMVKQFTPEVLQHLA 787

Query: 501 EVMDPGFVCSKIGVCP------SAYKLLLGTEKCVWGPSYWCQNMETAARCNAVDHC 551
           E  +P  +C  + VCP         +  LG + C  GP +WC +M+ A +C  V+ C
Sbjct: 786 EKDNPLELCQSLKVCPPEVTEEKTTQTNLGEDPCTHGPGFWCASMDNAKQCGMVEEC 616

 Score = 46.6 bits (109), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 27/83 (32%), Positives = 44/83 (53%)
 Frame = -1

Query: 316 LCQTCQFVMNKFSELIVNNATEELLVKGLSNACALLPDPARTKCQEVVGTFGPSLLDIFI 375
           +C  CQ + N  +E + + ATE  + K L +AC +LP+   + C+ +V  F P +L    
Sbjct: 966 MCIICQTLANYAAEGLSDPATESQIEKLLEDACTVLPENRVSDCKAMVKQFTPEVLQHLA 787

Query: 376 HEVNPSSLCGVIGLCAARPELVE 398
            + NP  LC  + +C   PE+ E
Sbjct: 786 EKDNPLELCQSLKVCP--PEVTE 724

 Score = 43.9 bits (102), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 26/76 (34%), Positives = 41/76 (53%)
 Frame = -1

Query: 63  CDICKTVVTEAGNLLKDNATQEEILHYLEKTCEWIHDSSLSASCKEVVDSYLPVILDMIK 122
           C IC+T+   A   L D AT+ +I   LE  C  + ++ +S  CK +V  + P +L  + 
Sbjct: 963 CIICQTLANYAAEGLSDPATESQIEKLLEDACTVLPENRVS-DCKAMVKQFTPEVLQHL- 790

Query: 123 GEMSNPGEVCSALNLC 138
            E  NP E+C +L +C
Sbjct: 789 AEKDNPLELCQSLKVC 742
>01365
          Length = 978

 Score = 51.2 bits (121), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 44/174 (25%), Positives = 63/174 (36%), Gaps = 3/174 (1%)
 Frame = +1

Query: 345 SNACALLPDPARTKCQEVVGTFGPSLLDIFIHEVNPSSLCGVIGLCAARPELVEALEQPA 404
           S  C LLP     KCQ  V   GP + DI    + P  +C  IGLC+A   +    E   
Sbjct: 343 SRMCPLLPS-GELKCQLEVQFLGPLVFDIISKGLTPRKVCIRIGLCSATVSIQGGGEHYR 519

Query: 405 PAIVSALLXXXXXXXXXXXXXXXXXXXHVPPQKNGGF---CEVCKKLVLYLEHNLEKNST 461
              +                         PPQ   G    C VC   V  +   L  N T
Sbjct: 520 STALQQ-----------------------PPQAXAGLDVHCRVCTFFVDSVITILTSNQT 630

Query: 462 KEEILAALEKGCSFLPDPYQKQCDDFVAEYEPLLLEILVEVMDPGFVCSKIGVC 515
            + +   ++  C   P     QCD F+ +Y  +L ++ ++   P  VC  +  C
Sbjct: 631 XKAVSQVVDALCPMAPHGLSAQCDAFLHQYAFMLGKMTMQHFIPHQVCHFLNQC 792
>06528
          Length = 969

 Score = 44.7 bits (104), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 37/161 (22%), Positives = 66/161 (40%), Gaps = 1/161 (0%)
 Frame = +2

Query: 358 KCQEVVGTFGPSLLDIFIHEVNPSSLCGVIGLCAARPELVEALEQPAPAIVSALLXXXXX 417
           +C ++V  F P +L + +   NP + C +I LC AR EL  A E   P            
Sbjct: 332 ECIQIVSEFLPKILYV-VASTNPRTFCEIINLCDAR-ELQSAPESLVP----------ED 475

Query: 418 XXXXXXXXXXXXXXHVPPQKNGGFCEVCKKLVLYLEHNLEKNSTKEEILAALEKGCSFLP 477
                         HV        C+ C          +  N+T++ +       C  LP
Sbjct: 476 AQFSVQTVGAADAQHV-------HCDACMLFAKLAVTFVTSNATEKGLSKLFNPACQTLP 634

Query: 478 DPYQKQCDDFVAEYEPLLLEILV-EVMDPGFVCSKIGVCPS 517
              Q++C   +AE+E  ++ ++V ++++P  +C  +  CP+
Sbjct: 635 SQLQQECKVLLAEHESAIVNMIVKKLINPEHICPFLDFCPT 757

 Score = 37.7 bits (86), Expect = 0.013,   Method: Compositional matrix adjust.
 Identities = 21/81 (25%), Positives = 38/81 (46%)
 Frame = +2

Query: 58  AKSLPCDICKTVVTEAGNLLKDNATQEEILHYLEKTCEWIHDSSLSASCKEVVDSYLPVI 117
           A+ + CD C      A   +  NAT++ +       C+ +  S L   CK ++  +   I
Sbjct: 512 AQHVHCDACMLFAKLAVTFVTSNATEKGLSKLFNPACQTL-PSQLQQECKVLLAEHESAI 688

Query: 118 LDMIKGEMSNPGEVCSALNLC 138
           ++MI  ++ NP  +C  L+ C
Sbjct: 689 VNMIVKKLINPEHICPFLDFC 751
>09010
          Length = 918

 Score = 29.6 bits (65), Expect = 2.9,   Method: Compositional matrix adjust.
 Identities = 14/40 (35%), Positives = 21/40 (52%)
 Frame = -1

Query: 33  CRDVKTAVDCGAVKHCQQMVWSKPTAKSLPCDICKTVVTE 72
           CR ++    C  +   QQ VW +P  +S PCD   + +TE
Sbjct: 144 CRHLEEPWRCHRL---QQRVWWRPGRRSAPCDEANSPLTE 34
>11272
          Length = 1530

 Score = 28.9 bits (63), Expect = 5.9,   Method: Compositional matrix adjust.
 Identities = 13/37 (35%), Positives = 20/37 (54%)
 Frame = -1

Query: 211  VKTNSSFIQGFVDHVKEDCDRLGPGVSDICKNYVDQY 247
             K   SFI  ++   K +  ++ P   DI ++YVDQY
Sbjct: 1287 TKGRKSFIDQYLQLYKSEHSKMSPQNVDIVEHYVDQY 1177
>07739
          Length = 858

 Score = 28.1 bits (61), Expect = 9.2,   Method: Compositional matrix adjust.
 Identities = 18/85 (21%), Positives = 34/85 (40%), Gaps = 9/85 (10%)
 Frame = +1

Query: 131 VCSALNLCQSLQEYL-AEQNQKQLESNKIPEVDMAR--------VVAPFMSNIPLLLYPQ 181
           +C+    CQS      A +       +K+  +   R        V  P    +PL    +
Sbjct: 514 ICTXRTTCQSATAASPAGRXNSSRADDKVAAISRTRPGXTIAVWVALPLPCRLPLYAEMK 693

Query: 182 DHPRSQPQPKANEDVCQDCMKLVSD 206
           +H +  P+P    ++C DC +L+ +
Sbjct: 694 EHQQKAPRPTFLGNICLDCWRLIEE 768
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|21362303|ref|NP_653104.1| synaptosomal-associated
protein, 47 [Mus musculus]
         (413 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

07328                                                                  85   7e-17
>07328
          Length = 1336

 Score = 84.7 bits (208), Expect = 7e-17,   Method: Compositional matrix adjust.
 Identities = 58/188 (30%), Positives = 93/188 (49%), Gaps = 27/188 (14%)
 Frame = -2

Query: 13   SYYLDLEKQWVSGKLTLTPHSLKFIVE----------------------KTEEVLVGLPL 50
            SYY + +++W+ G L   P  +KF+ +                        +   V L  
Sbjct: 1329 SYYHNDQRKWLYGHLVCCPLMVKFLTDTEGQRSRCADSNNDQGRDDHAPDNDSHEVVLQY 1150

Query: 51   SSIIEIRKESSLFIFGAITVLEKGQTKHWFSSLQPSRNVVFNVIEHFWRELLLSQPGTAA 110
             ++  ++K  S+ IF A+TV  +  T HWFSSL   R+ V+N +++F R+ LL    ++A
Sbjct: 1149 CNMKRVQKTRSMLIFHAVTVEMQDGTVHWFSSL-SDRHSVYNSLDYFSRQNLL--ENSSA 979

Query: 111  NIPSHVTR-----GQELIGLMANSQKRMEDTAKDLQQQSEQLDSVLKGLEKMESDLDVAD 165
            + P+H +      GQ L+    +S++ +   A DL  Q  QLD     L ++  DLDVAD
Sbjct: 978  HKPNHNSSTHTEIGQRLLQSAEDSERTLAAAAADLHGQGRQLDRAGVKLIELHEDLDVAD 799

Query: 166  RLLTELET 173
            RLL+ L T
Sbjct: 798  RLLSGLNT 775

 Score = 44.3 bits (103), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 55/204 (26%), Positives = 80/204 (39%), Gaps = 15/204 (7%)
 Frame = -1

Query: 225 KLGKLTVLVSALEIYDSCSLLLHRFEKEDVDDIKVHSPYEVSIRQRFIGKPDVAYQLISA 284
           +L  L V  + L +      LLH     ++  + V SP+EV + +    +P V+  ++SA
Sbjct: 640 RLCVLRVTRTGLTLMTLHQRLLHSXSWMELARVFVVSPWEVVLTRHVARRPAVSVSVVSA 461

Query: 285 KMPEVIPILEVQFSSKIELLEDALVLRNKVFASSAERHAASR-----PKGCTP------- 332
            +  V+ +L      K+  L D     +   A   E H ASR     PK  TP       
Sbjct: 460 GLLSVLQLL----XRKVSHLMDYQTPPDT--ACVGESHTASRESTMHPKHSTPSLQDHSQ 299

Query: 333 ---HRXXXXXXXXXXXXXXXKNLPLFSEGEAQELTQILSKMKGLALDTEAELERQDAALD 389
               R               K     S+ E   L   L  +K +A     EL  Q+ ALD
Sbjct: 298 SQQQRTVTPQDSTNVQLXQGKKSEEXSQEELAALCSKLGALKSMAGAVGEELTNQNQALD 119

Query: 390 GITVAVDRATLNVDKQNRRMRKLM 413
            +  +VD A   V    RR +KLM
Sbjct: 118 NMIHSVDHAESRVRDATRRTKKLM 47
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31980629|ref|NP_058074.2| vesicle-associated membrane
protein 8 [Mus musculus]
         (101 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

04498                                                                  82   7e-17
02964                                                                  82   8e-17
16746                                                                  48   9e-07
31401                                                                  25   7.4  
>04498
          Length = 1353

 Score = 81.6 bits (200), Expect = 7e-17,   Method: Compositional matrix adjust.
 Identities = 35/69 (50%), Positives = 55/69 (79%)
 Frame = +3

Query: 8   AGNDRVRNLQSEVEGVKNIMTQNVERILARGENLDHLRNKTEDLEATSEHFKTTSQKVAR 67
           AG+D V  LQS+V  VK +MTQN+E+++ RG+ L+ L +KTE+LEA++ +F+ TS+++ +
Sbjct: 78  AGSDNVSKLQSQVNEVKGVMTQNIEKVMERGDRLEDLMDKTEELEASAHNFQKTSRRIRK 257

Query: 68  KFWWKNVKM 76
           KFWW+N KM
Sbjct: 258 KFWWRNKKM 284
>02964
          Length = 832

 Score = 81.6 bits (200), Expect = 8e-17,   Method: Compositional matrix adjust.
 Identities = 35/69 (50%), Positives = 55/69 (79%)
 Frame = -3

Query: 8   AGNDRVRNLQSEVEGVKNIMTQNVERILARGENLDHLRNKTEDLEATSEHFKTTSQKVAR 67
           AG+D V  LQS+V  VK +MTQN+E+++ RG+ L+ L +KTE+LEA++ +F+ TS+++ +
Sbjct: 752 AGSDNVSKLQSQVNEVKGVMTQNIEKVMERGDRLEDLMDKTEELEASAHNFQKTSRRIRK 573

Query: 68  KFWWKNVKM 76
           KFWW+N KM
Sbjct: 572 KFWWRNKKM 546
>16746
          Length = 340

 Score = 48.1 bits (113), Expect = 9e-07,   Method: Compositional matrix adjust.
 Identities = 19/54 (35%), Positives = 35/54 (64%)
 Frame = +1

Query: 23 VKNIMTQNVERILARGENLDHLRNKTEDLEATSEHFKTTSQKVARKFWWKNVKM 76
          V  IM  NV R+  RG+ L+ L++K++ L ++++ F++ S+ +    WWKN +M
Sbjct: 1  VMGIMRDNVNRVAERGDRLEDLQDKSDSLSSSADMFRSRSKSLHHNMWWKNCRM 162
>31401
          Length = 647

 Score = 25.0 bits (53), Expect = 7.4,   Method: Compositional matrix adjust.
 Identities = 12/33 (36%), Positives = 19/33 (57%)
 Frame = -1

Query: 44  LRNKTEDLEATSEHFKTTSQKVARKFWWKNVKM 76
           + ++T      S HF TT+QKV  +   KN+K+
Sbjct: 491 IHHETFPFNPKSSHFSTTNQKVKCQQQPKNIKV 393
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|34328204|ref|NP_035820.2| valyl-tRNA synthetase [Mus
musculus]
         (1263 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

10621                                                                  86   7e-17
20405                                                                  65   1e-10
23211                                                                  52   1e-06
14979                                                                  37   0.039
18652                                                                  31   2.5  
08903                                                                  30   5.3  
>10621
          Length = 1304

 Score = 86.3 bits (212), Expect = 7e-17,   Method: Composition-based stats.
 Identities = 44/121 (36%), Positives = 62/121 (51%), Gaps = 1/121 (0%)
 Frame = +2

Query: 90  SRAAVLVQQWVSYADTELIPAACGATLPALGL-RGPGQDPQAALGALGKALNPLEDWLRL 148
           + AA  V QW+ +AD E++P+ C    P LG+ +   Q+ + A   + KAL  L D+L  
Sbjct: 269 AEAAAQVSQWIDFADNEILPSVCTWVFPCLGITQFNKQETERAKAQVTKALTVLNDYLLT 448

Query: 149 HTYLAGXXXXXXXXXXXXXXXXXFRYVLDPSARRIWGNVTRWFNTCVRQPEFRAVLGEVA 208
            TYL G                 +  V+DP  R+ + NV RWF T V QP F+AV G+V 
Sbjct: 449 RTYLVGESVTQADISLACNLIMLYEQVMDPEFRKPFQNVNRWFTTLVNQPNFKAVAGDVT 628

Query: 209 L 209
           L
Sbjct: 629 L 631
>20405
          Length = 766

 Score = 65.5 bits (158), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 39/115 (33%), Positives = 55/115 (47%), Gaps = 1/115 (0%)
 Frame = -1

Query: 96  VQQWVSYADTELIPAACGATLPALG-LRGPGQDPQAALGALGKALNPLEDWLRLHTYLAG 154
           + QW S+AD+EL+PA+C    P LG ++   Q+ + A   L  AL  L+  L   T+L  
Sbjct: 502 IYQWASWADSELLPASCAWVFPYLGIMQFNKQNVERAKNDLLAALKVLDGHLLTRTFLVT 323

Query: 155 XXXXXXXXXXXXXXXXXFRYVLDPSARRIWGNVTRWFNTCVRQPEFRAVLGEVAL 209
                            F+ VLD S R    NV RWF T   QP+  +V+G + L
Sbjct: 322 ERITLADIIVFTTLIHAFQNVLDASIRSSLVNVQRWFLTLANQPQVASVVGNIVL 158
>23211
          Length = 1156

 Score = 52.4 bits (124), Expect = 1e-06,   Method: Composition-based stats.
 Identities = 27/71 (38%), Positives = 34/71 (47%)
 Frame = +1

Query: 139 LNPLEDWLRLHTYLAGXXXXXXXXXXXXXXXXXFRYVLDPSARRIWGNVTRWFNTCVRQP 198
           L  L D+L   TYL G                 +  V+DP  R+ + NV RWF T V QP
Sbjct: 1   LTVLNDYLLTRTYLVGESVTQADISLACNLIMLYEQVMDPEFRKPFQNVNRWFXTLVNQP 180

Query: 199 EFRAVLGEVAL 209
            F+AV G+V L
Sbjct: 181 NFKAVAGDVTL 213
>14979
          Length = 1133

 Score = 37.4 bits (85), Expect = 0.039,   Method: Compositional matrix adjust.
 Identities = 35/148 (23%), Positives = 65/148 (43%), Gaps = 1/148 (0%)
 Frame = -1

Query: 325 PSVSAPNPRGVFMMCIPPPNVTGSLHLGHALTNAIQ-DSLTRWHRMRGETTLWNPGCDHA 383
           P +   N R + ++    P V    HLG+ +   +  D  +R+ R+R    L+  G D  
Sbjct: 926 PVLPKKNKRNI-LITSALPYVNNVPHLGNIIGCVLSADVFSRFCRLRNYNVLYVCGTDEY 750

Query: 384 GIATQVVVEKKLWKERGLNRHQLGREAFLEEVWKWKAEKGDRIYHQLKKLGSSLDWDRAC 443
           G AT+    K L  E G+   Q+              +K ++++ ++ +   ++D+D   
Sbjct: 749 GTATET---KAL--EEGVTPQQI-------------CDKYNKLHTEIYQW-FNIDFDYFG 627

Query: 444 FTMDPKLSATVTEAFVRLHEEGVIYRST 471
            T  P+ +    + F RLHE G I + +
Sbjct: 626 RTTTPQQTEIAQDIFWRLHERGFILKDS 543
>18652
          Length = 759

 Score = 31.2 bits (69), Expect = 2.5,   Method: Compositional matrix adjust.
 Identities = 31/113 (27%), Positives = 48/113 (42%)
 Frame = +1

Query: 983  DRWIRSRLTEAVRLSNEGFQAYDFPAITTAQYSFWLYELCDVYLECLKPVLNGVDQVAAE 1042
            DR+I+ R  E+V   +EGF    +  +  A     L+++    L+ L PVL       A 
Sbjct: 442  DRFIQIRGFESVDDGSEGFPVDHWCIMGQATDDGRLHKV-SWPLDWLAPVL-----YLAA 603

Query: 1043 CARQTLYTCLDVGLRLLSPFMPFVTEELFQRLPRRTPKAPASLCVTPYPEPSE 1095
                  +  L+ G   L      V   L Q +P R  + P+S+C  P+  PS 
Sbjct: 604  LGHSVSHCLLEQG-HALGAV*GAVVHSLVQXIPIRAERTPSSVCPQPHRAPSH 759
>08903
          Length = 1766

 Score = 30.4 bits (67), Expect = 5.3,   Method: Compositional matrix adjust.
 Identities = 24/76 (31%), Positives = 33/76 (43%)
 Frame = -2

Query: 543  DVAVAVHPKDPRYQHLKGKCVVHPFLSRSLPIVFDDFVDMEFGTGAVKITPAHDQNDYEV 602
            DVA  VHP  PRY    G C V  +      +V  D   ++  T AV+ T  +       
Sbjct: 1150 DVASYVHPHKPRY----GTCGV-QYTKDGASMVGSDVYRVDGQTTAVEATXGY------- 1007

Query: 603  GQRHRLEAISIMDSKG 618
            GQRH  + + +   KG
Sbjct: 1006 GQRHTQQCVVVALHKG 959
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|83816905|ref|NP_001033027.1| peroxisomal short-chain
alcohol dehydrogenase isoform 1 [Mus musculus]
         (279 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

12758                                                                  84   7e-17
03060                                                                  75   4e-14
30783                                                                  45   5e-11
28229                                                                  45   6e-11
18041                                                                  57   1e-08
20818                                                                  52   3e-07
11922                                                                  48   4e-06
35613                                                                  47   7e-06
03983                                                                  45   3e-05
05194                                                                  40   0.001
27168                                                                  37   0.013
12878                                                                  31   0.47 
>12758
          Length = 804

 Score = 84.0 bits (206), Expect = 7e-17,   Method: Compositional matrix adjust.
 Identities = 55/192 (28%), Positives = 102/192 (53%), Gaps = 4/192 (2%)
 Frame = -1

Query: 87  IVCHVGKAEDREKLITTALKRHRGIDILVSNAAVNPFFGNLMDVTEEVWDKVLSINVTAT 146
           +V  + K +D ++++   +K+   ++ILV+ A +    GN+ + + + +D++ + NV + 
Sbjct: 726 LVGDLTKEDDTKRVVEETVKQFGRLNILVNCAGIIEL-GNIENTSLDQYDRMFNTNVRSV 550

Query: 147 AMMIKAVVPEMEKRXXXXXXXXXXXAGFTRFPSLGPYNVSKTALLGLTKNFAAELAPKNI 206
             +    VP +               G   FP++  Y ++K+A+   T+  A ELAPK +
Sbjct: 549 YHLTMLAVPHL-VNTQGNIVNVSSVNGMRSFPNVLAYCMAKSAIDQFTRCVALELAPKKV 373

Query: 207 RVNCLAPGLIKTRFSSVL-WEEKAREDFI---KEAMQIRRLGKPEDCAGIVSFLCSEDAS 262
           RVN + PG+I +        +++A   F+   KE   + R G+PE+ A  ++FL SEDAS
Sbjct: 372 RVNGVNPGVIISELQKRGGLDDEAYAKFLERSKETHALGRPGQPEEVARXIAFLASEDAS 193

Query: 263 YINGETVVVGGG 274
           +I G ++ V GG
Sbjct: 192 FITGASLPVDGG 157
>03060
          Length = 1893

 Score = 74.7 bits (182), Expect = 4e-14,   Method: Compositional matrix adjust.
 Identities = 53/213 (24%), Positives = 99/213 (46%), Gaps = 5/213 (2%)
 Frame = -1

Query: 15   WMSVRMASSGLTRRNPLSNKVALVTASTDGIGFAIARRLAEDGAHVVVSSRKQQNVDRAV 74
            W  +R      TR   +  KV LVT ++ G+G A A+   + G  V+++ R  + ++   
Sbjct: 1743 WHRIRTFIKLRTRAADIQGKVVLVTGASSGLGKACAKVFHQHGCQVILAGRSVERLNAVK 1564

Query: 75   ATL---QGE--GLSVTGIVCHVGKAEDREKLITTALKRHRGIDILVSNAAVNPFFGNLMD 129
              L   +GE      + +   +      ++L   A++    +D++++NA ++ + G + D
Sbjct: 1563 DYLTKSEGEVKACEPSVLAMDLEDLNSLQQLAERAVELFGKVDVVINNAGIS-YRGCIED 1387

Query: 130  VTEEVWDKVLSINVTATAMMIKAVVPEMEKRXXXXXXXXXXXAGFTRFPSLGPYNVSKTA 189
             + +V  K++++N      +IK ++P M+ R            G    P    Y+ SK A
Sbjct: 1386 TSIQVDQKLMAVNYFGHVALIKGLLPHMQARNSGHIVGISSVQGKISIPYRSAYSASKHA 1207

Query: 190  LLGLTKNFAAELAPKNIRVNCLAPGLIKTRFSS 222
            L        AEL+   I+V+ L+PG IKT  S+
Sbjct: 1206 LQAFFDCLRAELSCTKIKVSLLSPGYIKTNLSN 1108
>30783
          Length = 765

 Score = 45.4 bits (106), Expect(2) = 5e-11,   Method: Compositional matrix adjust.
 Identities = 29/100 (29%), Positives = 50/100 (50%), Gaps = 6/100 (6%)
 Frame = +1

Query: 180 LGPYNVSKTALLGLTKNFAAELAPKNIRVNCLAPGLIKT---RFSSVLWEEKAREDFIKE 236
           +G Y +SK A+   T+  A ELAP  +RVN + PG + +   R     + ++    F++ 
Sbjct: 232 VGVYCMSKAAMDMFTQCLALELAPHGVRVNSVNPGSVVSMIYRRGPSGYNDEDYAKFLES 411

Query: 237 AMQIRRLGK---PEDCAGIVSFLCSEDASYINGETVVVGG 273
                 LG    PED A  ++FL S  + +++G  + + G
Sbjct: 412 QKGKHPLGDVAVPEDVANSIAFLASNMSRFVSGTGLFIDG 531

 Score = 38.9 bits (89), Expect(2) = 5e-11,   Method: Compositional matrix adjust.
 Identities = 20/50 (40%), Positives = 31/50 (62%)
 Frame = +2

Query: 111 IDILVSNAAVNPFFGNLMDVTEEVWDKVLSINVTATAMMIKAVVPEMEKR 160
           +DILV+NA V  F     D TEE +D+++ IN+ +   + K + PE+ KR
Sbjct: 32  LDILVNNAGVARFVKPC-DTTEEQYDEIMDINMKSVFFLSKLLAPELIKR 178
>28229
          Length = 633

 Score = 45.1 bits (105), Expect(2) = 6e-11,   Method: Compositional matrix adjust.
 Identities = 29/96 (30%), Positives = 45/96 (46%), Gaps = 1/96 (1%)
 Frame = -1

Query: 151 KAVVPEMEKRXXXXXXXXXXXAGFTRFPSLGPYNVSKTALLGLTKNFAAELAPKNIRVNC 210
           KA +P + K            AG   FP    Y +SK AL   TK  + ELAP+ +RVN 
Sbjct: 306 KAALPHLLK-TKGAVVNVSSCAGICHFPGALSYGISKAALDQFTKIVSLELAPQGVRVNS 130

Query: 211 LAPGLIKTRFSS-VLWEEKAREDFIKEAMQIRRLGK 245
           + PG + T   S +   ++A +   + A+    +G+
Sbjct: 129 VNPGFVVTNIHSRIGIVDEAYKSLHERAINSHPMGR 22

 Score = 38.9 bits (89), Expect(2) = 6e-11,   Method: Compositional matrix adjust.
 Identities = 35/113 (30%), Positives = 58/113 (51%), Gaps = 4/113 (3%)
 Frame = -2

Query: 41  STDGIGFAIARRLAEDGAHVVVSSRKQQNVD--RAVATLQGEGLSVTGIVCHVGKAEDRE 98
           ++ GIG AIA+ LA +GA + +  R   N++  R     Q  G+ V  +V  V    D  
Sbjct: 632 ASSGIGVAIAQVLAREGAVLSLVGRNVTNLEATRTTLQQQTTGVQVLNVVADV--TTDSA 459

Query: 99  KLITTALKRHRGIDILVSNAAVNPFFGN--LMDVTEEVWDKVLSINVTATAMM 149
            +I   +  +  ID+LV+NA +    GN  L+D+    +D VL+ N+ A  ++
Sbjct: 458 AIIQQTINHYGRIDVLVNNAGI---LGNGPLIDLDIAEFDAVLNTNLRAIVLL 309
>18041
          Length = 547

 Score = 56.6 bits (135), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 51/185 (27%), Positives = 82/185 (44%), Gaps = 7/185 (3%)
 Frame = -2

Query: 41  STDGIGFAIARRLAEDGAHVVVSSRKQQNVDRAVATLQGEGLSVTGIVCHVGKAEDREKL 100
           STDGIG   A +LAE G  +V+ SR  + +  AVA    E +    +   V  A+ +   
Sbjct: 543 STDGIGKCFALQLAEKGLDIVLISRNPEKL-SAVAK---EIVDQHKVSVKVITADFKNAD 376

Query: 101 ITTALKRH-RGID--ILVSNAAV----NPFFGNLMDVTEEVWDKVLSINVTATAMMIKAV 153
           I   +KR   G+D  ILV+N  +    NP +    D  E+    ++++N+ A   M   V
Sbjct: 375 IYDNIKRQLTGLDIGILVNNVGMLNRRNPGYFCEADDFEQFHQDIINVNILACVQMTGIV 196

Query: 154 VPEMEKRXXXXXXXXXXXAGFTRFPSLGPYNVSKTALLGLTKNFAAELAPKNIRVNCLAP 213
           +PEM +R           A     P    Y+ +K  +   T+    E + + + +  L P
Sbjct: 195 LPEMLERKRGLIINIASGAAIRPLPFFSVYSGTKAFISHFTQALNMEYSSQGVTIQLLIP 16

Query: 214 GLIKT 218
            L+ T
Sbjct: 15  NLVAT 1
>20818
          Length = 613

 Score = 51.6 bits (122), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 30/91 (32%), Positives = 48/91 (52%), Gaps = 8/91 (8%)
 Frame = +1

Query: 193 LTKNFAAELAPKNIRVNCLAPGLIKTRFSSVLWEEKAREDFIK--------EAMQIRRLG 244
           LTK+ + E A   +R+NC+APG       S ++ E A  ++          E++ + R G
Sbjct: 40  LTKSLSIEWASDGVRINCVAPG-------SSIYSETAAANYGSLDIFSKNLESVPLNRFG 198

Query: 245 KPEDCAGIVSFLCSEDASYINGETVVVGGGT 275
             E+ +  V FL S  A++I GET+ V GG+
Sbjct: 199 TTEEVSAAVCFLLSPAAAFITGETIKVDGGS 291
>11922
          Length = 2153

 Score = 47.8 bits (112), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 38/134 (28%), Positives = 67/134 (50%), Gaps = 7/134 (5%)
 Frame = +1

Query: 31  LSNKVALVTASTDGIGFAIARRLAEDGAHVVVSSRKQQNVDRAVATLQGEGLSV-----T 85
           L  K   +T ++ GIG AIA +LA+DGA++V++++  +   +   T+      V      
Sbjct: 94  LVGKTVFITGASRGIGKAIAVKLAKDGANIVIAAKTAEAHPKLPGTIYTAAKEVEEAGGK 273

Query: 86  GIVCHVG-KAEDREKL-ITTALKRHRGIDILVSNAAVNPFFGNLMDVTEEVWDKVLSINV 143
            + C V  + ED+ K+ +  A  +  GIDILV+NA+     G L    +  +D +  IN 
Sbjct: 274 ALPCIVDIRNEDQVKVAVKAAADKFGGIDILVNNASAISLTGTLQTPMKR-YDLMNGINA 450

Query: 144 TATAMMIKAVVPEM 157
             T +  +  +P +
Sbjct: 451 RGTYLCSQVCLPYL 492
>35613
          Length = 977

 Score = 47.4 bits (111), Expect = 7e-06,   Method: Compositional matrix adjust.
 Identities = 48/186 (25%), Positives = 78/186 (41%), Gaps = 2/186 (1%)
 Frame = +1

Query: 31  LSNKVALVTASTDGIGFAIARRLAEDGAHVVVSSRKQQNVDRAVATLQGEGLSVTGIVCH 90
           L +K  L+T    G G A+A+ L EDG H V+++  Q + D A          +T I   
Sbjct: 79  LRDKTVLITGCDTGFGHALAKSLHEDGCH-VIATVYQPDGDGAKRLRDVSTDRMTVIPLD 255

Query: 91  VGKAEDREKLI--TTALKRHRGIDILVSNAAVNPFFGNLMDVTEEVWDKVLSINVTATAM 148
           V   +  EK +     L  H G+  LV+NA  N F G +   T   +  V +IN+     
Sbjct: 256 VSSDDSVEKCLRHVKQLCEHSGLWGLVNNAGHN-FVGEVELTTMRQYLMVANINIFGMVR 432

Query: 149 MIKAVVPEMEKRXXXXXXXXXXXAGFTRFPSLGPYNVSKTALLGLTKNFAAELAPKNIRV 208
             +A +P + +             G    P    YN++K A    ++    E+    ++V
Sbjct: 433 TTRAFLP-LLRHATGRIVNVTSIKGQLSTPMNAAYNITKYAGETFSEITQMEMKQFGVKV 609

Query: 209 NCLAPG 214
           + + PG
Sbjct: 610 SIVEPG 627
>03983
          Length = 1099

 Score = 45.1 bits (105), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 50/231 (21%), Positives = 90/231 (38%), Gaps = 12/231 (5%)
 Frame = +2

Query: 6   RLLGGWTQAWMSVRMASSGLTRRNPLSNKVALVTASTDGIGFAIARRLAEDGAHVVVSSR 65
           +++  W +A +   + S     R  +  +  L+T +  G+G  +A R    G  +V+   
Sbjct: 101 KVMYYWCEAIVKCILPSKFF--RKSVEGQRVLITGAGSGLGKLMAYRFMGLGCDLVLWDI 274

Query: 66  KQQNVDRAVATLQGEGLSVTGIVCHVGKAEDREKLITTALKRHRGIDILVSNAAVNPFFG 125
             + ++ A+    G+ +S       +   E   K      +   G+DILV+NA +    G
Sbjct: 275 NTEAIE-AMERDMGQQVSCKAYTVDLSSREQIYKAADQVKREVGGVDILVNNAGIVT--G 445

Query: 126 -NLMDVTEEVWDKVLSINVTATAMMIKAVVPEMEKRXXXXXXXXXXXAGFTRFPSLGPYN 184
              +D  + + +K + +N  A    +KA +P M  +           AG      L  Y 
Sbjct: 446 RKFLDCPDSLIEKTMEVNSNAHFWTVKAFLPNMLAQNKGHIISIASSAGLFGVTGLADYC 625

Query: 185 VSKTALLGLTKNFAAEL---APKNIRVNCLAPGLI--------KTRFSSVL 224
            SK A +G  ++   EL       +    + P  I        KTRF  +L
Sbjct: 626 ASKFAAVGFDESLRFELEAMGKTGVHTTVVCPYFINTGMFDGVKTRFPLIL 778
>05194
          Length = 1075

 Score = 39.7 bits (91), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 23/77 (29%), Positives = 37/77 (48%)
 Frame = +1

Query: 157 MEKRXXXXXXXXXXXAGFTRFPSLGPYNVSKTALLGLTKNFAAELAPKNIRVNCLAPGLI 216
           M KR           AG   FP L  Y+ SK  + GL++   +E+A   ++V C+ PG +
Sbjct: 22  MVKRESGHIINISSDAGRKGFPGLAVYSGSKFFVEGLSQAMRSEVADSGVKVTCIQPGDV 201

Query: 217 KTRFSSVLWEEKAREDF 233
           KT    +  + +A E +
Sbjct: 202 KTPLFGLSTDREAIEKY 252
>27168
          Length = 665

 Score = 36.6 bits (83), Expect = 0.013,   Method: Compositional matrix adjust.
 Identities = 27/94 (28%), Positives = 41/94 (43%), Gaps = 4/94 (4%)
 Frame = +3

Query: 31  LSNKVALVTASTDGIGFAIARRLAEDGAHVVVSSRK----QQNVDRAVATLQGEGLSVTG 86
           L  +VAL+T +  GIGF  AR LA  G  ++++ R     Q+ +DR              
Sbjct: 180 LHGRVALITGANCGIGFETARSLALHGCEIILACRNLATAQEAIDRIAVERPAARARCRT 359

Query: 87  IVCHVGKAEDREKLITTALKRHRGIDILVSNAAV 120
               +G   D +K +    +    ID L+ NA V
Sbjct: 360 ASLDLGSLSDVKKFVEQIRQSVGHIDYLILNAGV 461
>12878
          Length = 847

 Score = 31.2 bits (69), Expect = 0.47,   Method: Compositional matrix adjust.
 Identities = 22/68 (32%), Positives = 33/68 (48%), Gaps = 2/68 (2%)
 Frame = +3

Query: 191 LGLTK-NFAAELAPKNI-RVNCLAPGLIKTRFSSVLWEEKAREDFIKEAMQIRRLGKPED 248
            GL+  N+A + A  +I R  C     IK   S   W++  REDF    ++I  LG P  
Sbjct: 117 FGLSHFNWAVQGANYHILRTGCFP--YIKYHCSRRPWQDLEREDFFFTCLKIVNLGIPTL 290

Query: 249 CAGIVSFL 256
             G+ S++
Sbjct: 291 AYGVGSWM 314
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|26986583|ref|NP_758478.1| coiled-coil and C2 domain
containing 2A [Mus musculus]
         (1633 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

17289                                                                  87   8e-17
14385                                                                  30   6.3  
>17289
          Length = 1007

 Score = 86.7 bits (213), Expect = 8e-17,   Method: Composition-based stats.
 Identities = 38/74 (51%), Positives = 53/74 (71%)
 Frame = -3

Query: 1555 IEDDHRAELLKQLGDYRFSGFPLHMPYSEVKPLVEAVYSTGVHNIDLPNVEFALAVYIHP 1614
            I+     EL +    Y+ SGFP+++P+ ++  + EAV+STGVH+ +  NVEFALAVY+H 
Sbjct: 1005 IDQQDLVELEESFKSYKVSGFPINVPFVDLNTITEAVFSTGVHSQETSNVEFALAVYVHG 826

Query: 1615 YPKNVLSVWIYVAS 1628
            Y  NVLS+WIYVAS
Sbjct: 825  YSNNVLSIWIYVAS 784
>14385
          Length = 676

 Score = 30.4 bits (67), Expect = 6.3,   Method: Composition-based stats.
 Identities = 13/29 (44%), Positives = 18/29 (62%)
 Frame = +1

Query: 1462 PLRINFDVTKPKLWKSFFSRSLPYPGLSS 1490
            PL +NF +  P  ++SF S  +P PGL S
Sbjct: 481  PLHLNFSL*TPTFFQSFLSLPIPQPGLGS 567
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|33469980|ref|NP_081551.2| pentatricopeptide repeat
domain 3 [Mus musculus]
         (685 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

26149                                                                  74   8e-17
29956                                                                  31   1.6  
>26149
          Length = 437

 Score = 74.3 bits (181), Expect(2) = 8e-17,   Method: Compositional matrix adjust.
 Identities = 41/98 (41%), Positives = 62/98 (63%), Gaps = 4/98 (4%)
 Frame = +1

Query: 352 ALQILREMKHIGIEPSLATYHHIIHLFYPRDLSAIKMPSLIIYDIMNELEGRTF---SPQ 408
            L+ L EMK +GIEPSLA++ H++ +FYP +++     S I+Y I++ LEG+     SPQ
Sbjct: 7   VLKTLNEMKSVGIEPSLASWKHVLTVFYPNEMA----DSNILYKIVDYLEGKDLTLTSPQ 174

Query: 409 DLDDGRFFQLAMS-VCSSLRDLELAYQVHRLLNTGDNR 445
           DLD   FF  AM   C +L D+ELA ++  ++N+  N 
Sbjct: 175 DLD---FFAHAMKRCCQNLHDVELALRIDNIVNSNQNN 279

 Score = 31.2 bits (69), Expect(2) = 8e-17,   Method: Compositional matrix adjust.
 Identities = 14/49 (28%), Positives = 24/49 (48%)
 Frame = +3

Query: 442 GDNRKLVGHDPLRKVYYSKFFSLICSLEQIDVTLKWYKDLIPSVFLPHY 490
           GDNR          +YYS     +C+ E +D  ++ Y+ + P V+ P +
Sbjct: 288 GDNRA-------SNIYYSFLLQAVCTFESLDKIMEVYQRVTPHVWAPDF 413
>29956
          Length = 348

 Score = 31.2 bits (69), Expect = 1.6,   Method: Composition-based stats.
 Identities = 13/27 (48%), Positives = 15/27 (55%)
 Frame = +3

Query: 540 HPPELQVAFADCAADIKSTYEDQSARQ 566
           H P LQ  F DCAAD+  + E    RQ
Sbjct: 147 H*PNLQEGFKDCAADVSKSAEQCDVRQ 227
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6755763|ref|NP_035698.1| THO complex 4 [Mus musculus]
         (255 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

23225                                                                  83   9e-17
13822                                                                  49   2e-06
30672                                                                  48   3e-06
00302                                                                  47   7e-06
08958                                                                  45   4e-05
01278                                                                  43   1e-04
17775                                                                  43   2e-04
02064                                                                  42   2e-04
08816                                                                  42   3e-04
03059                                                                  39   0.002
28605                                                                  34   0.056
03406                                                                  31   0.40 
25691                                                                  31   0.59 
28652                                                                  30   0.80 
26197                                                                  29   1.5  
37645                                                                  28   3.7  
31265                                                                  28   4.7  
>23225
          Length = 1278

 Score = 83.2 bits (204), Expect = 9e-17,   Method: Compositional matrix adjust.
 Identities = 54/135 (40%), Positives = 69/135 (51%), Gaps = 13/135 (9%)
 Frame = +2

Query: 132 KKAAVHYDRSGRSLGTADVHFERKADALKAMKQYNGVPLDGRPMNIQLV-TSQIDT---Q 187
           ++AAVHYDRSGRSLGTA+V + R+ DA+KAMKQYN VPLDGR M+IQLV  + + +    
Sbjct: 464 EQAAVHYDRSGRSLGTAEVIYVRRTDAVKAMKQYNNVPLDGRAMSIQLVGATDVGSSLQN 643

Query: 188 RRP---------AQSIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKQQLSA 238
           RRP         +Q                                        K   S 
Sbjct: 644 RRPNIGGGGGGFSQRGSSRGRGGSGGGDRGGFSRGRGGSRGRGRGGRGRGGRSDKTTPSL 823

Query: 239 EELDAQLDAYNARMD 253
           EEL+AQLDAYN++M+
Sbjct: 824 EELNAQLDAYNSKME 868

 Score = 60.5 bits (145), Expect = 7e-10,   Method: Compositional matrix adjust.
 Identities = 35/85 (41%), Positives = 43/85 (50%), Gaps = 19/85 (22%)
 Frame = +1

Query: 76  YSRPKQLPDKWQHDLFDSX-----------XXXXXXXXXXXKLLVSNLDFGVSDADIQEL 124
           Y RPK+LPD WQHD+FD                        KLLVSNLDFGV+D+DIQEL
Sbjct: 265 YQRPKELPDVWQHDMFDGSDGGYRRGPGPMRSASGVASTSGKLLVSNLDFGVNDSDIQEL 444

Query: 125 FAEF------GTLK--KAAVHYDRS 141
                     G+L+  +  + Y RS
Sbjct: 445 LQSLVS*TSSGSLRQVRKVIGYRRS 519

 Score = 27.3 bits (59), Expect = 6.3,   Method: Compositional matrix adjust.
 Identities = 11/14 (78%), Positives = 13/14 (92%)
 Frame = +1

Query: 1  MADKMDMSLDDIIK 14
          M DK+D+SLDDIIK
Sbjct: 61 MGDKLDLSLDDIIK 102
>13822
          Length = 963

 Score = 48.9 bits (115), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 28/89 (31%), Positives = 50/89 (56%)
 Frame = -1

Query: 106 KLLVSNLDFGVSDADIQELFAEFGTLKKAAVHYDRSGRSLGTADVHFERKADALKAMKQY 165
           +L VSN+ F   +AD+++L   FGT+    + ++  G S G   V F   A+A +A  + 
Sbjct: 339 RLHVSNIPFRFREADLRQLLGPFGTILDVEIIFNERG-SKGFGFVTFAHSAEAERARDKM 163

Query: 166 NGVPLDGRPMNIQLVTSQIDTQRRPAQSI 194
           NG  ++GR + +   T+++ T++  A SI
Sbjct: 162 NGTVVEGRKIEVNNATARVMTKKVAAPSI 76
>30672
          Length = 877

 Score = 48.1 bits (113), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 24/72 (33%), Positives = 38/72 (52%)
 Frame = +3

Query: 106 KLLVSNLDFGVSDADIQELFAEFGTLKKAAVHYDRSGRSLGTADVHFERKADALKAMKQY 165
           +L++ NL F   +ADI+  F +FGT+ +  +   +  RS G A V F     A KA+   
Sbjct: 408 RLIIRNLAFKCKEADIRSHFGKFGTISEVTIPLKQGDRSRGFAFVQFTEVKAAQKAISDM 587

Query: 166 NGVPLDGRPMNI 177
           NG  +  RP+ +
Sbjct: 588 NGTAIMDRPVAV 623
>00302
          Length = 927

 Score = 47.0 bits (110), Expect = 7e-06,   Method: Compositional matrix adjust.
 Identities = 24/78 (30%), Positives = 43/78 (55%), Gaps = 1/78 (1%)
 Frame = -1

Query: 107 LLVSNLDFGVSDADIQELFAEFGTLKKAAVHYDR-SGRSLGTADVHFERKADALKAMKQY 165
           L +  L     +  ++E+F  +G + +  V YDR +GRS G A V+F+   DA +A  + 
Sbjct: 459 LGIFGLSLYTQERGLREVFGRYGHISEVQVVYDRQTGRSRGFAFVYFKSSEDAHEAKDRC 280

Query: 166 NGVPLDGRPMNIQLVTSQ 183
           NG+ +DGR + +    ++
Sbjct: 279 NGIEIDGRKIRVDFSITE 226
>08958
          Length = 680

 Score = 44.7 bits (104), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 29/76 (38%), Positives = 44/76 (57%), Gaps = 4/76 (5%)
 Frame = +2

Query: 107 LLVSNLDFGVSDADIQELFAEFGTLKKAAVHYDRSGRSLGTADVHFERKADALKAMKQYN 166
           L V NL   VS+  +++ F +FG L++A V  D  GRS G   V F RK  A +A+++ N
Sbjct: 296 LKVKNLHPYVSNELLEQAFTQFGDLERAIVIVDERGRSTGEGVVEFVRKPGAQQALRRIN 475

Query: 167 -GVPLDG---RPMNIQ 178
            GV L G   +P+ ++
Sbjct: 476 EGVFLFGADPKPIEVE 523
>01278
          Length = 1082

 Score = 42.7 bits (99), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 23/73 (31%), Positives = 43/73 (58%), Gaps = 1/73 (1%)
 Frame = +2

Query: 107 LLVSNLDFGVSDADIQELFAEFGTLKKAAVHYDR-SGRSLGTADVHFERKADALKAMKQY 165
           + V+NL     ++D+QELF  FG + +  +  D+ +G+S G A ++F R+ DA +A+   
Sbjct: 641 IRVTNLSEDTRESDLQELFRPFGPISRIYLAKDKVTGQSKGFAFINFHRREDASRAIAGV 820

Query: 166 NGVPLDGRPMNIQ 178
           +G   D   +N++
Sbjct: 821 SGFGYDHLILNVE 859
>17775
          Length = 1282

 Score = 42.7 bits (99), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 25/79 (31%), Positives = 41/79 (51%)
 Frame = -2

Query: 107 LLVSNLDFGVSDADIQELFAEFGTLKKAAVHYDRSGRSLGTADVHFERKADALKAMKQYN 166
           L V NLD  + D  +++ F+ FGT+  A +  +  GRS G   V F    +A KA+ + N
Sbjct: 336 LYVKNLDDSIDDERLRKEFSNFGTITSAKIMTE-GGRSKGFGFVCFSSPEEATKAVTEMN 160

Query: 167 GVPLDGRPMNIQLVTSQID 185
           G  +  +P+ + L   + D
Sbjct: 159 GRIIVAKPLYVALAQRKED 103

 Score = 38.9 bits (89), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 20/71 (28%), Positives = 38/71 (53%)
 Frame = -2

Query: 107 LLVSNLDFGVSDADIQELFAEFGTLKKAAVHYDRSGRSLGTADVHFERKADALKAMKQYN 166
           + + NLD  + +  + + F+ FG +    +  D  G S G   VHFE +  A +A+ + N
Sbjct: 924 VFIKNLDKTIDNKALYDTFSAFGNILSCKIACDEQG-SKGYGFVHFETEEAARQAIDKVN 748

Query: 167 GVPLDGRPMNI 177
           G+ L+G+ + +
Sbjct: 747 GMLLNGKKVYV 715

 Score = 35.0 bits (79), Expect = 0.027,   Method: Compositional matrix adjust.
 Identities = 26/72 (36%), Positives = 40/72 (55%), Gaps = 1/72 (1%)
 Frame = -2

Query: 107  LLVSNLDFGVSDADIQELFAEFGTLKKAAVHYDR-SGRSLGTADVHFERKADALKAMKQY 165
            L V +L   V++A + E F+  G +    V  D  + RSLG A V+F++ ADA +A+   
Sbjct: 1188 LYVGDLHPDVTEAMLFEKFSTAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDTM 1009

Query: 166  NGVPLDGRPMNI 177
            N   + GRP+ I
Sbjct: 1008 NFDTVKGRPIRI 973
>02064
          Length = 1195

 Score = 42.0 bits (97), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 21/71 (29%), Positives = 40/71 (56%)
 Frame = +1

Query: 109 VSNLDFGVSDADIQELFAEFGTLKKAAVHYDRSGRSLGTADVHFERKADALKAMKQYNGV 168
           V NL + ++  D++E F E G +K + +  D+ GRS G   V F  + DA++A+   +  
Sbjct: 91  VKNLPYAITWQDLRERFQEIGVVKYSEITMDK-GRSTGQGLVRFATEDDAVRAINSMDRT 267

Query: 169 PLDGRPMNIQL 179
             +GR + +++
Sbjct: 268 RYEGRTIGVKM 300
>08816
          Length = 566

 Score = 41.6 bits (96), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 23/73 (31%), Positives = 42/73 (57%)
 Frame = +1

Query: 107 LLVSNLDFGVSDADIQELFAEFGTLKKAAVHYDRSGRSLGTADVHFERKADALKAMKQYN 166
           + V N+ F ++  +++E F + G +K + +  D+ GR  G A V F   ADA++A+   +
Sbjct: 55  VTVRNVPFSLTWQELRERFQDIGDVKFSEILMDQ-GRPSGDAVVRFGTSADAMRAINLVD 231

Query: 167 GVPLDGRPMNIQL 179
           G  +DGR + + L
Sbjct: 232 GTRIDGRTVRVVL 270
>03059
          Length = 1154

 Score = 38.9 bits (89), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 26/70 (37%), Positives = 38/70 (54%), Gaps = 2/70 (2%)
 Frame = -2

Query: 106 KLLVSNLDFGVSDADIQELFAEFGTLKKAAVHYDR--SGRSLGTADVHFERKADALKAMK 163
           K+ V  L   V+   IQE+F+ +GT+K   +  DR     S G A V +E   DA KA+K
Sbjct: 667 KVHVGRLTRNVNKDHIQEIFSLYGTIKFIDLPNDRIHPNTSKGHAYVEYENPEDAEKAVK 488

Query: 164 QYNGVPLDGR 173
             +G  +DG+
Sbjct: 487 YMDGGQIDGQ 458
>28605
          Length = 697

 Score = 34.3 bits (77), Expect = 0.056,   Method: Compositional matrix adjust.
 Identities = 19/64 (29%), Positives = 36/64 (56%), Gaps = 1/64 (1%)
 Frame = -3

Query: 106 KLLVSNLDFG-VSDADIQELFAEFGTLKKAAVHYDRSGRSLGTADVHFERKADALKAMKQ 164
           ++ V+NL     S+A++QELF+++G +    VH++R G       V F  + +  +A++ 
Sbjct: 566 RVFVANLSSDETSEAELQELFSKYGNVLDTLVHHNRYGF------VQFSTEEEGRRAVEA 405

Query: 165 YNGV 168
            NG 
Sbjct: 404 MNGY 393
>03406
          Length = 1292

 Score = 31.2 bits (69), Expect = 0.40,   Method: Compositional matrix adjust.
 Identities = 13/35 (37%), Positives = 20/35 (57%)
 Frame = +3

Query: 106 KLLVSNLDFGVSDADIQELFAEFGTLKKAAVHYDR 140
           K+ V  LD GV   D++  FA+FG +    + YD+
Sbjct: 489 KIFVGKLDPGVPQEDVESYFAKFGKVVNVELPYDK 593
>25691
          Length = 768

 Score = 30.8 bits (68), Expect = 0.59,   Method: Compositional matrix adjust.
 Identities = 14/39 (35%), Positives = 25/39 (64%)
 Frame = -2

Query: 141 SGRSLGTADVHFERKADALKAMKQYNGVPLDGRPMNIQL 179
           +G+SLG   V+++R+ DA KA+   NG+ L  + + + L
Sbjct: 407 TGQSLGYGFVNYKRQEDADKAIHTLNGLRLQNKTIKVSL 291
>28652
          Length = 918

 Score = 30.4 bits (67), Expect = 0.80,   Method: Compositional matrix adjust.
 Identities = 19/61 (31%), Positives = 31/61 (50%)
 Frame = -2

Query: 107 LLVSNLDFGVSDADIQELFAEFGTLKKAAVHYDRSGRSLGTADVHFERKADALKAMKQYN 166
           L V NL   V++ D++E F  +G +++     D          VH+E + DALKA+   +
Sbjct: 194 LYVRNLTGDVTEDDLKEKFGAYGKVERVKKIKD-------YGFVHYEDREDALKALDDLH 36

Query: 167 G 167
           G
Sbjct: 35  G 33
>26197
          Length = 1365

 Score = 29.3 bits (64), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 12/35 (34%), Positives = 19/35 (54%)
 Frame = -3

Query: 106  KLLVSNLDFGVSDADIQELFAEFGTLKKAAVHYDR 140
            +  V  LD GV   D++  FA+FG +    + YD+
Sbjct: 1048 RFFVGKLDPGVPQEDVESYFAKFGKVVNVELPYDK 944
>37645
          Length = 1070

 Score = 28.1 bits (61), Expect = 3.7,   Method: Compositional matrix adjust.
 Identities = 11/38 (28%), Positives = 23/38 (60%)
 Frame = -2

Query: 142 GRSLGTADVHFERKADALKAMKQYNGVPLDGRPMNIQL 179
           GRS+G   V F  + DA++A+   +    +GR +++++
Sbjct: 970 GRSMGQGLVRFATEDDAVRAINSMDRTRFEGRTIDVKM 857
>31265
          Length = 540

 Score = 27.7 bits (60), Expect = 4.7,   Method: Compositional matrix adjust.
 Identities = 18/73 (24%), Positives = 34/73 (46%)
 Frame = +2

Query: 107 LLVSNLDFGVSDADIQELFAEFGTLKKAAVHYDRSGRSLGTADVHFERKADALKAMKQYN 166
           L V NL    ++  ++++F+            +R  +    A VHF  + DA+KAM   +
Sbjct: 164 LXVRNLMLTTTEETLKDVFSR----AAGGREIERVKKIRDYAFVHFRSREDAIKAMDVTD 331

Query: 167 GVPLDGRPMNIQL 179
           G  ++G  + + L
Sbjct: 332 GSTIEGSQVEVVL 370
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|22094115|ref|NP_035616.1| signal transducer and
activator of transcription 3 isoform 3 [Mus musculus]
         (722 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

11920                                                                  84   1e-16
27851                                                                  51   1e-06
22001                                                                  45   1e-04
27860                                                                  30   3.2  
>11920
          Length = 931

 Score = 84.3 bits (207), Expect = 1e-16,   Method: Compositional matrix adjust.
 Identities = 70/221 (31%), Positives = 100/221 (45%), Gaps = 18/221 (8%)
 Frame = +3

Query: 501 WDQVAEVLSWQFSSTTKRGLSIEQLTTLAEKLLGPGVNYSG-CQITWAKFCKENMAGKGF 559
           WD++A  L       T + LS   L  LA KLLG   N S    +++A+FC+  +     
Sbjct: 30  WDKLARELDLTCRYITCQPLSPNHLGLLASKLLGTHWNVSNNSYVSFAEFCENILPNHPC 209

Query: 560 -----------------SFWVWLDNIIDLVKKYILALWNEGYIMGFISKERERAILSTKP 602
                            +FW WL + + L+K ++  LW+   I GFIS+ +    L  + 
Sbjct: 210 REEEKEKKSGKKSKSRCTFWDWLSDALYLIKNHLQELWDNRLIEGFISRNQAAERLMGQD 389

Query: 603 PGTFLLRFSESSKEGGVTFTWVEKDISGKTQIQSVEPYTKQQLNNMSFAEIIMGYKIMDA 662
            GTFL+RFS+ SK G +T  +V  D  G   I  +EP     L     A+ I        
Sbjct: 390 VGTFLIRFSD-SKCGAITIAFV--DTPGALPIH-LEPMDAAFLQATRLADFI------KT 539

Query: 663 TNILVSPLVYLYPDIPKEEAFGKYCRPESQEHPEADPGSAA 703
           +N L +    LYP+IPK  AF KY     Q  P+A   SA+
Sbjct: 540 SNKLKT----LYPNIPKHTAFAKYYSQPKQPDPQARYHSAS 650
>27851
          Length = 663

 Score = 51.2 bits (121), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 28/120 (23%), Positives = 59/120 (49%), Gaps = 4/120 (3%)
 Frame = +2

Query: 1   MAQWNQLQQLDTRYLEQLHQLYSDSFPMELRQFLAPWIESQDW----AYAASKESHATLV 56
           M +W+ + Q ++    QL + Y   FP+E+R FL+ W ESQ+W        + E+   ++
Sbjct: 5   MPRWSHIVQ-NSDXFSQLQEFYQPRFPIEVRYFLSQWFESQNWQGIDPDNPTNEAIGAML 181

Query: 57  FHNLLGEIDQQYSRFLQESNVLYQHNLRRIKQFLQSRYLEKPMEIARIVARCLWEESRLL 116
              L G ++++      E  ++ +  L + +Q  +S +   P+   +++  C  +E  L+
Sbjct: 182 LKELCGLLNERVQELSGEDFMIIRIRLDQTRQNFESTFQNSPLGFLKVMKECAQKEEELM 361
>22001
          Length = 528

 Score = 45.1 bits (105), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 36/128 (28%), Positives = 61/128 (47%), Gaps = 2/128 (1%)
 Frame = +3

Query: 202 QLEQMLTALDQMRRSIVSELAGLLSAMEYVQKTLTDEELADWKRRQQIACIGGPPNIC-L 260
           QL ++   L Q+R    S    ++  ++ +Q+++ D+EL  WK+RQQ++  GG  +   L
Sbjct: 18  QLSELGQQLLQLRVQNASMYQEIIEQLQVLQRSVLDDELIGWKKRQQLSGNGGILDSAEL 197

Query: 261 DRLENWITSLAESQLQTRXXXXXXXXXXXXVSYKGDPIVQH-RPMLEERIVELFRNLMKS 319
           + L+ W   LAE     R            +       VQ   P L + I  +  +L+ S
Sbjct: 198 NDLQMWCEHLAEIIWNIRQQIKRTSILRAQLPINLPTGVQDLLPELNDIITGMLSSLVTS 377

Query: 320 AFVVERQP 327
            F+VE+QP
Sbjct: 378 TFIVEQQP 401
>27860
          Length = 845

 Score = 30.0 bits (66), Expect = 3.2,   Method: Compositional matrix adjust.
 Identities = 16/44 (36%), Positives = 21/44 (47%)
 Frame = -3

Query: 403 SLSAEFKHLTLREQRCGNGGRANCDASLIVTEELHLITFETEVY 446
           S+S  FKH+        NGGR    +       LHLIT++ E Y
Sbjct: 714 SISFRFKHMR------SNGGRTAASSHFENERALHLITYQIEKY 601
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|22122695|ref|NP_666277.1| JTV1 [Mus musculus]
         (280 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

20465                                                                  83   1e-16
12716                                                                  60   1e-09
17387                                                                  37   0.006
06860                                                                  33   0.17 
06833                                                                  30   0.93 
21882                                                                  29   2.4  
30446                                                                  28   3.2  
>20465
          Length = 842

 Score = 83.2 bits (204), Expect = 1e-16,   Method: Compositional matrix adjust.
 Identities = 46/97 (47%), Positives = 65/97 (67%), Gaps = 3/97 (3%)
 Frame = +2

Query: 167 IEGEGNIARFLFSLFGQKHN---AVTLTLIDSWVDIAMFQLREGSSKEKAAVFRSMNSAL 223
           I+GE NIAR+L  L    ++    VT T ID  +D+A  QL +G++KEK+AV R++N+ L
Sbjct: 32  IQGEANIARYLSRLLQPAYDDVDIVTATHIDEVLDMAQQQLIQGNNKEKSAVLRTLNARL 211

Query: 224 GRSPWLVGNELTVADVVLWSVLQQTGGSSGAAPTNVQ 260
           G+  WLVG  L++ADVV+WS LQ    +S  AP NV+
Sbjct: 212 GKGSWLVGANLSLADVVVWSALQGAKIAS-EAPANVK 319
>12716
          Length = 548

 Score = 59.7 bits (143), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 37/148 (25%), Positives = 72/148 (48%), Gaps = 3/148 (2%)
 Frame = +1

Query: 8   SEPSLQALESRQDDILKRLYELKAAVDGLSKMIHTPDADLDVTNILQADEPTTLATNTLD 67
           +E  L  L+ RQ  +L  L +L+ ++  L++              L A  P+ ++ +   
Sbjct: 130 AEDRLSKLQQRQQLVLTDLQQLQKSIQLLAQQRGIS---------LTATPPSNISASAAS 282

Query: 68  LNSVLGKDYG---ALKDIVINANPASPPXXXXXXXXXXCERYRVLSTVHTHSSVKNVPEN 124
           ++++     G   AL+D+VI+A+P+ PP            +++VL++   HSS  + P+ 
Sbjct: 283 VSNMSAAKMGSGQALQDLVISADPSCPPLSLLVLLKQLSNQHQVLTSTFVHSSAVDTPQE 462

Query: 125 LVKCFGEQARKQSRHEYQLGFTLIWKNV 152
           L          ++R ++QLG TL+WK +
Sbjct: 463 LRSFLPSSRSCEARCKFQLGLTLVWKKI 546
>17387
          Length = 493

 Score = 37.4 bits (85), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 23/92 (25%), Positives = 42/92 (45%), Gaps = 5/92 (5%)
 Frame = +1

Query: 193 IDSWVDIAMFQLREGSSKEKAA-VFRSMNSALGRSPWLVGNELTVADVV----LWSVLQQ 247
           +D W++  + Q+   S  + A  V + +NS L    + V +  TVAD+V    L++V  +
Sbjct: 124 VDQWLEYCVTQITHCSQAQHATHVLQELNSYLSDKVYFVTHHPTVADIVIYHGLFNVFTK 303

Query: 248 TGGSSGAAPTNVQRWLKSCENLAPFSTALQLL 279
              S      ++ RW  + +       +LQ L
Sbjct: 304 LAYSEKEKYIHLSRWFDNIQQDQRIRQSLQRL 399
>06860
          Length = 498

 Score = 32.7 bits (73), Expect = 0.17,   Method: Compositional matrix adjust.
 Identities = 18/56 (32%), Positives = 26/56 (46%), Gaps = 6/56 (10%)
 Frame = +1

Query: 207 GSSKEKAAV------FRSMNSALGRSPWLVGNELTVADVVLWSVLQQTGGSSGAAP 256
           GSS +  AV      F  +      SP+ VGN +T+ADV  +  + Q    +G  P
Sbjct: 103 GSSNQDGAVIDQVVHFNKLLEENSDSPFFVGNSITLADVYTYDFIFQVKKVTGYDP 270
>06833
          Length = 882

 Score = 30.4 bits (67), Expect = 0.93,   Method: Compositional matrix adjust.
 Identities = 12/31 (38%), Positives = 18/31 (58%)
 Frame = +3

Query: 226 SPWLVGNELTVADVVLWSVLQQTGGSSGAAP 256
           SP+ VGN +T+ADV  +  + Q    +G  P
Sbjct: 537 SPFFVGNSITLADVYXYDXIFQVKKVTGYDP 629
>21882
          Length = 431

 Score = 28.9 bits (63), Expect = 2.4,   Method: Compositional matrix adjust.
 Identities = 17/62 (27%), Positives = 24/62 (38%), Gaps = 11/62 (17%)
 Frame = -1

Query: 164 MCPI--EGEGNIARFLFSLFGQKHNAVTLTLIDSWVDI---------AMFQLREGSSKEK 212
           MCPI  E   +   FL   F  +H  + L  +D+W+            M Q+  G    K
Sbjct: 353 MCPIDLENRNHYHVFLLLTFPHQHILIALCFVDAWMHA*NILFX*APDMLQVIHGQCMRK 174

Query: 213 AA 214
            A
Sbjct: 173 MA 168
>30446
          Length = 489

 Score = 28.5 bits (62), Expect = 3.2,   Method: Compositional matrix adjust.
 Identities = 15/47 (31%), Positives = 25/47 (53%), Gaps = 1/47 (2%)
 Frame = -3

Query: 108 VLSTVHTHSSVKNVPENLVKCFGEQARKQSRHEYQLGFTLI-WKNVP 153
           V  TVH   + + +  +L++    Q R+QSRH +Q   T+  W+  P
Sbjct: 142 VWPTVHHPQARQCMSHDLIQFLQRQNRRQSRHRFQSHHTVRSWRRQP 2
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|27370224|ref|NP_766407.1| DIP2 disco-interacting
protein 2 homolog B [Mus musculus]
         (1340 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

36633                                                                  86   1e-16
02291                                                                  37   0.063
14096                                                                  33   0.88 
03181                                                                  32   1.4  
14024                                                                  32   1.5  
03756                                                                  31   3.1  
04867                                                                  31   3.4  
>36633
          Length = 355

 Score = 85.5 bits (210), Expect = 1e-16,   Method: Compositional matrix adjust.
 Identities = 49/115 (42%), Positives = 68/115 (59%), Gaps = 5/115 (4%)
 Frame = +2

Query: 457 GRAILSMNGLSYGVIRVNTEDKNSALTVQDVGHVMPGGMMCIVKPDGLPQLCRTDEIGEI 516
           GR ILSM GLS+GV+RV+ E+  ++LT+QD G VMPG +M ++K DG P +C+TDE+G  
Sbjct: 23  GRGILSMQGLSHGVVRVDNENSLTSLTLQDCGQVMPGALMVVIKLDGSPTVCKTDEVGSC 202

Query: 517 CVSSRTGGMMYFGLAGVTKNTFEVIPVTSSGSPVGDVPFIRSGL-----LGFVGP 566
                T G  Y+GL G   +     P   S SP+ +  +  S +     L FVGP
Sbjct: 203 VCVRATRGTSYWGLQGSHPHP----PSRCSPSPLTEDRWETSSMSAPVSLDFVGP 355
>02291
          Length = 3161

 Score = 36.6 bits (83), Expect = 0.063,   Method: Compositional matrix adjust.
 Identities = 33/132 (25%), Positives = 51/132 (38%), Gaps = 20/132 (15%)
 Frame = -1

Query: 829  GCLYAGCIPV---TVRPPHAQNLTATLPTVRMVVDVSKAACVLTTQTLMRLLKSR----- 880
            GC+YAG +     T   P A    A      ++V          +Q L ++L+ R     
Sbjct: 3161 GCIYAGGLATGIYTTNSPEACEFVAASSQANVIV-------AENSQQLKKILQVRHNLPH 3003

Query: 881  -----------EAAAAVDVKTWPAIIDT-DDLPRKRLPQLYKPPTPEMLAYLDFSVSTTG 928
                       + A A DV +W   +   DD+P   L +  K  +P     L ++  TTG
Sbjct: 3002 LKAIVQYTGQVDEAHAKDVLSWEQFMKAGDDVPDSVLDERIKALSPNKCCVLIYTSGTTG 2823

Query: 929  MLTGVKMSHSAV 940
               GV +SH  +
Sbjct: 2822 TPKGVMLSHDNI 2787
>14096
          Length = 983

 Score = 33.1 bits (74), Expect = 0.88,   Method: Compositional matrix adjust.
 Identities = 19/61 (31%), Positives = 29/61 (47%)
 Frame = -3

Query: 118 PCLTGLDVTGKPVYTLTYGKLWSRSLKLAYTLLNKLGTKNEPVLKPGDRVALVYPNNDPV 177
           P  T   + GKPV    +  LW++ + +  T L     K+  V + G+R+A V   N P 
Sbjct: 327 PQRTKSRLRGKPVLVFVFRTLWNKLIXMHMTCLLCSWAKSARVTEKGERIACVTVFNYPA 148

Query: 178 M 178
           M
Sbjct: 147 M 145
>03181
          Length = 700

 Score = 32.3 bits (72), Expect = 1.4,   Method: Composition-based stats.
 Identities = 14/31 (45%), Positives = 20/31 (64%), Gaps = 2/31 (6%)
 Frame = +3

Query: 232 LPKTQNGEIV--QFKGWPRLKWVVTDSKYLS 260
           +PK +N +I+  QF  W R  W V+D+K LS
Sbjct: 216 MPKIRNEKIMFWQFPAWSRWSWQVSDTKTLS 308
>14024
          Length = 655

 Score = 32.3 bits (72), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 26/106 (24%), Positives = 39/106 (36%)
 Frame = +3

Query: 1121 PQSLLLSESGKILPGVKVVIVNPETKGPVGDSHLGEIWVNSPHTASGYYTIYDSETLQAD 1180
            P S LL+  GK LPG +  I+N +  G       GE+ +   H   GY +         +
Sbjct: 165  PDSTLLNSIGKSLPGCESKIINQDANGH------GELCIRGRHVFMGYIS---------N 299

Query: 1181 HFNTRLSFGDAAQTLWARTGYLGFVRRTELTAATGERHDALYVVGA 1226
               T  S  D     W  +G L ++        TG   + +   G 
Sbjct: 300  KEKTEESLDDDC---WLHSGDLAYIDDKGYVCLTGRLKELIITAGG 428
>03756
          Length = 992

 Score = 31.2 bits (69), Expect = 3.1,   Method: Compositional matrix adjust.
 Identities = 23/81 (28%), Positives = 36/81 (44%), Gaps = 16/81 (19%)
 Frame = +2

Query: 889 KTWPAIIDTDDLPRKRLPQLYK----------------PPTPEMLAYLDFSVSTTGMLTG 932
           KTWP   D  DL  +R  +L                  PP P+ LA L ++  TTG   G
Sbjct: 602 KTWPQ--DIRDLANERKVELLTFKEIESIGTKDTRDPIPPKPDDLATLCYTSGTTGDPKG 775

Query: 933 VKMSHSAVNALCRAIKLQCEL 953
           V ++H+    +  ++ LQ ++
Sbjct: 776 VMLTHANFLIMLSSVYLQAKV 838
>04867
          Length = 1835

 Score = 30.8 bits (68), Expect = 3.4,   Method: Compositional matrix adjust.
 Identities = 15/38 (39%), Positives = 22/38 (57%)
 Frame = +3

Query: 564 VGPGSLVFVVGKMDGLLMVSGRRHNADDIVATGLAVES 601
           +GP S+  V+ K   L  V+ +RHN D+ V   LA+ S
Sbjct: 714 LGPSSIAVVLSKFPNLEKVTLQRHNVDEAVLKQLALTS 827
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|58037191|ref|NP_081571.1| RAB28, member RAS oncogene
family [Mus musculus]
         (221 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

17511                                                                  82   1e-16
26083                                                                  80   6e-16
05468                                                                  80   7e-16
34468                                                                  75   2e-14
13901                                                                  74   3e-14
08428                                                                  72   2e-13
33794                                                                  69   2e-12
14456                                                                  68   3e-12
33374                                                                  65   2e-11
07465                                                                  63   1e-10
33380                                                                  62   1e-10
27191                                                                  58   3e-09
01398                                                                  55   2e-08
13745                                                                  55   3e-08
01972                                                                  51   4e-08
13750                                                                  53   8e-08
07580                                                                  52   2e-07
19006                                                                  52   3e-07
12339                                                                  50   1e-06
01095                                                                  49   2e-06
24619                                                                  49   2e-06
11728                                                                  48   2e-06
19046                                                                  48   4e-06
29380                                                                  47   9e-06
34359                                                                  46   1e-05
26536                                                                  44   4e-05
19656                                                                  44   4e-05
32723                                                                  44   4e-05
00552                                                                  42   3e-04
14119                                                                  41   3e-04
35581                                                                  41   5e-04
25618                                                                  40   7e-04
08153                                                                  36   0.012
09827                                                                  36   0.012
14775                                                                  34   0.042
34597                                                                  34   0.045
18208                                                                  34   0.047
10862                                                                  33   0.094
16653                                                                  30   0.69 
12440                                                                  28   2.4  
33605                                                                  28   2.5  
07059                                                                  27   5.1  
>17511
          Length = 483

 Score = 82.4 bits (202), Expect = 1e-16,   Method: Compositional matrix adjust.
 Identities = 45/123 (36%), Positives = 69/123 (56%), Gaps = 2/123 (1%)
 Frame = -3

Query: 13  LKIVVLGDGTSGKTSLATCFAQETFGKQYKQTIGLDFFLRRITLPGNLNVTLQVWDIGGQ 72
           LK+++LGD   GKTSL   +  + F  QYK TIG DF  + + +   L VT+Q+WD  GQ
Sbjct: 364 LKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRL-VTMQIWDTAGQ 188

Query: 73  TIGGKMLDKYIYGAQGILLVYDITNYQSFENLEDWYS--VVKTVSEESETQPLVALVGNK 130
                +   +  GA   +LV+D+T   +F +L+ W    +++    + E  P V ++GNK
Sbjct: 187 ERFQSLGVAFYRGADCCVLVFDVTMPNTFRSLDSWRDEFLIQASPRDPENFPFV-VIGNK 11

Query: 131 IDL 133
           IDL
Sbjct: 10  IDL 2
>26083
          Length = 432

 Score = 80.1 bits (196), Expect = 6e-16,   Method: Compositional matrix adjust.
 Identities = 45/120 (37%), Positives = 67/120 (55%)
 Frame = +1

Query: 11  RQLKIVVLGDGTSGKTSLATCFAQETFGKQYKQTIGLDFFLRRITLPGNLNVTLQVWDIG 70
           R+ K+V LG+ + GKTSL T F  ++F   Y+ TIG+DF  + + L  +  + LQ+WD  
Sbjct: 73  RKFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLE-DRTIRLQLWDTA 249

Query: 71  GQTIGGKMLDKYIYGAQGILLVYDITNYQSFENLEDWYSVVKTVSEESETQPLVALVGNK 130
           GQ     ++  YI  +   ++VYDITN  SF     W   V+T   E  +  ++ LVGNK
Sbjct: 250 GQERFRSLIPSYIRDSSVAVVVYDITNANSFHQTSKWIDDVRT---ERGSDVIIMLVGNK 420
>05468
          Length = 1558

 Score = 80.1 bits (196), Expect = 7e-16,   Method: Compositional matrix adjust.
 Identities = 45/149 (30%), Positives = 77/149 (51%), Gaps = 2/149 (1%)
 Frame = -3

Query: 7    ESQDRQLKIVVLGDGTSGKTSLATCFAQETFGKQYKQTIGLDFFLRRITLPGNLNVTLQV 66
            E ++   KI+V+G+  +GKTS+   +  + F + Y+ TIG+DF L+ +    +  + LQ+
Sbjct: 1556 EKKEHLYKILVIGELGTGKTSIIKRYVHQFFSQHYRATIGVDFALKVLNWDADTLIRLQL 1377

Query: 67   WDIGGQTIGGKMLDKYIYGAQGILLVYDITNYQSFENLEDWYSVVKTVSEESETQPL-VA 125
            WDI GQ   G M   Y   A G  +V+D+T   +F+ +  W + + +  + ++  P+   
Sbjct: 1376 WDIAGQERFGNMTRVYYKEAVGAFVVFDVTRASTFDAVTKWKNDLDSKVQLADGSPVPCV 1197

Query: 126  LVGNKIDLEHMRTVKADKHL-RFCQENGF 153
            L+ NK D      V     +  FC E GF
Sbjct: 1196 LLANKCDQAKEGLVNNTSQMDEFCSEKGF 1110
>34468
          Length = 1502

 Score = 74.7 bits (182), Expect = 2e-14,   Method: Compositional matrix adjust.
 Identities = 55/180 (30%), Positives = 81/180 (45%), Gaps = 12/180 (6%)
 Frame = +1

Query: 1   MSDSEEESQDRQLKIVVLGDGTSGKTSLATCFAQETFGKQYKQTIGLDFFLRRITLPGNL 60
           M   E+++Q R  KI+V+GD   GKT L   F    F  + + TIG+DF  + I +    
Sbjct: 460 MKVVEKQTQRRIFKIIVIGDSNVGKTCLTYRFCLGKFPDKTEATIGVDFREKSIQVDSE- 636

Query: 61  NVTLQVWDIGGQTIGGK-MLDKYIYGAQGILLVYDITNYQSFENLEDWYSVVKTVSEESE 119
           ++ LQ+WD  GQ    K M+  Y      ++ VYD+T   SFEN+  W        EE +
Sbjct: 637 HLKLQLWDTAGQERFRKSMVQHYYRNVHAVVFVYDMTKMSSFENMPAWI-------EECD 795

Query: 120 TQPLVA-----LVGNKIDLEHMRTVKADKHLRFCQENGFSSHFVSAKTG------DSVFL 168
              L       LVGNK D+     V  +   +F   +       SAK        D++F+
Sbjct: 796 RHNLTKYIPRILVGNKCDVVERIAVNTNLAQKFADAHNMPLFETSAKDDEKANHVDAIFM 975
>13901
          Length = 962

 Score = 74.3 bits (181), Expect = 3e-14,   Method: Compositional matrix adjust.
 Identities = 34/100 (34%), Positives = 56/100 (56%)
 Frame = -3

Query: 8   SQDRQLKIVVLGDGTSGKTSLATCFAQETFGKQYKQTIGLDFFLRRITLPGNLNVTLQVW 67
           S++   K++++GD T GKTS    +  ++F + YK TIG+DF L+ I      N+ LQ+W
Sbjct: 300 SEEVLFKVIIIGDPTVGKTSFVQRYVNDSFRRDYKMTIGVDFALKVIRWSDKCNIKLQLW 121

Query: 68  DIGGQTIGGKMLDKYIYGAQGILLVYDITNYQSFENLEDW 107
           DI GQ     M   Y   A   ++++D+T   +++N   W
Sbjct: 120 DIAGQERFTSMTRVYYKDAHACIVMFDLTQKNTYQNAIRW 1
>08428
          Length = 1109

 Score = 72.0 bits (175), Expect = 2e-13,   Method: Compositional matrix adjust.
 Identities = 38/131 (29%), Positives = 68/131 (51%)
 Frame = -3

Query: 9    QDRQLKIVVLGDGTSGKTSLATCFAQETFGKQYKQTIGLDFFLRRITLPGNLNVTLQVWD 68
            Q R +K+ +LGD   GK+S+   F   ++    + TIG  F  + + + G      Q+WD
Sbjct: 1080 QMRDVKVCLLGDSGVGKSSIVLRFVTGSYRPSQESTIGASFMSKSLVVDG-AGYRFQIWD 904

Query: 69   IGGQTIGGKMLDKYIYGAQGILLVYDITNYQSFENLEDWYSVVKTVSEESETQPLVALVG 128
              GQ     +   Y  GA   ++VYD+T  ++F++++ W   +++    +    ++A+ G
Sbjct: 903  TAGQEKFRALAPMYYRGAAAAVIVYDVTRPRTFKSVKSWIQELRSFGPPNI---VLAIAG 733

Query: 129  NKIDLEHMRTV 139
            NK DLE +R V
Sbjct: 732  NKCDLEELREV 700
>33794
          Length = 779

 Score = 68.6 bits (166), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 39/98 (39%), Positives = 54/98 (55%)
 Frame = -1

Query: 62  VTLQVWDIGGQTIGGKMLDKYIYGAQGILLVYDITNYQSFENLEDWYSVVKTVSEESETQ 121
           V LQ+WD  GQ     ++  Y  GAQGI+LVYDITN  SF+ ++ W   +K V E +   
Sbjct: 650 VKLQIWDTSGQGRFCTIIRSYSRGAQGIILVYDITNKWSFDGIDRW---LKEVEEHAPGI 480

Query: 122 PLVALVGNKIDLEHMRTVKADKHLRFCQENGFSSHFVS 159
           P V LVGN++ L + R V A +   +   N  S   +S
Sbjct: 479 PKV-LVGNRLHLAYKRQVAAKQAETYASRNNMSCFEIS 369
>14456
          Length = 1867

 Score = 68.2 bits (165), Expect = 3e-12,   Method: Compositional matrix adjust.
 Identities = 64/212 (30%), Positives = 92/212 (43%), Gaps = 3/212 (1%)
 Frame = -1

Query: 10   DRQLKIVVLGDGTSGKTSLATCFAQETFGKQYKQTIGLDFFLRRITLPGNLNVTLQVWDI 69
            D+QLK      G  GK+SL   F    F  Q   TIG++F L +  +  +   T+Q+WD 
Sbjct: 1132 DKQLK-----QGGVGKSSLMNRFVSNKFDAQSFHTIGVEF-LNKDVVVDDETYTMQIWDT 971

Query: 70   GGQTIGGKMLDKYIYGAQGILLVYDITNYQSFENLEDWYSVVKTVSE--ESETQPLVALV 127
             GQ     +   +  GA   LL + + + QSF NL  W       ++  +  T P V L 
Sbjct: 970  AGQERFKSLRTPFYRGADCCLLTFSVDSMQSFRNLSMWRKEFLYYADIQDGVTFPFVVL- 794

Query: 128  GNKIDLEHMRTVKADKHLRFCQENGFSSHF-VSAKTGDSVFLCFQKVAAEILGIKLNKAE 186
            GNKID+E  R V  ++   +C  N  + +F  SAK   +V   F      +        E
Sbjct: 793  GNKIDVEG-RQVTNEEARSWCTANSNAPYFETSAKDATNVEKAFLAAVQRL-------RE 638

Query: 187  IEQSQRVVKADIVNYNQEPLSRTVNPPRSSMC 218
            +E  Q V  A   + N   L+R      SS C
Sbjct: 637  VEDQQEVKTA---HGNTVDLNRAARGKSSSCC 551
>33374
          Length = 489

 Score = 64.7 bits (156), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 37/117 (31%), Positives = 58/117 (49%)
 Frame = +1

Query: 50  FLRRITLPGNLNVTLQVWDIGGQTIGGKMLDKYIYGAQGILLVYDITNYQSFENLEDWYS 109
           FL +     +  V  ++WD  GQ     +   Y  GAQ  ++VYDITN  +F   + W  
Sbjct: 139 FLTQTVCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNQDTFGRAKTW-- 312

Query: 110 VVKTVSEESETQPLVALVGNKIDLEHMRTVKADKHLRFCQENGFSSHFVSAKTGDSV 166
            VK +  ++    ++AL GNK DL + R V+ ++   + +EN       SAKT  +V
Sbjct: 313 -VKELQRQASPNIVIALAGNKADLANKRMVEFEEAQAYAEENSLLFMETSAKTAMNV 480
>07465
          Length = 1103

 Score = 62.8 bits (151), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 38/108 (35%), Positives = 56/108 (51%)
 Frame = +3

Query: 26  TSLATCFAQETFGKQYKQTIGLDFFLRRITLPGNLNVTLQVWDIGGQTIGGKMLDKYIYG 85
           +S+   + +  F K YK+TIG+DF  R+I + G  +V L +WD  GQ     +   Y  G
Sbjct: 240 SSMIQRYCKGIFTKDYKKTIGVDFLERQIEVGGE-DVRLMLWDTAGQEEFDAITKAYYRG 416

Query: 86  AQGILLVYDITNYQSFENLEDWYSVVKTVSEESETQPLVALVGNKIDL 133
           AQ  +L +   +  SFE LE W   V    E+   +  + +V NKIDL
Sbjct: 417 AQACVLAFSTVDRDSFEALETWKRKV----EDEVGEIGMVIVQNKIDL 548
>33380
          Length = 282

 Score = 62.4 bits (150), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 33/76 (43%), Positives = 45/76 (59%)
 Frame = +3

Query: 62  VTLQVWDIGGQTIGGKMLDKYIYGAQGILLVYDITNYQSFENLEDWYSVVKTVSEESETQ 121
           V LQ+WD  GQ     +   Y  GA G +L+YD+TN +SF  ++DW + +KT S ++   
Sbjct: 60  VKLQIWDTAGQERYRTITTAYYRGAMGFILMYDVTNEESFNAVQDWCTQIKTYSWDN--- 230

Query: 122 PLVALVGNKIDLEHMR 137
             V LVGNK DLE  R
Sbjct: 231 AQVVLVGNKCDLEDER 278
>27191
          Length = 443

 Score = 58.2 bits (139), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 29/107 (27%), Positives = 60/107 (56%)
 Frame = +1

Query: 25  KTSLATCFAQETFGKQYKQTIGLDFFLRRITLPGNLNVTLQVWDIGGQTIGGKMLDKYIY 84
           KT L   F +  F + Y+ T+G+D+  +  T+ G +++ + +WD+ G      + ++   
Sbjct: 1   KTCLIKHFCESKFNQGYQPTVGVDYGFKIQTVNG-VDMRVHMWDLSGSNEYLDVRNELYT 177

Query: 85  GAQGILLVYDITNYQSFENLEDWYSVVKTVSEESETQPLVALVGNKI 131
           G+  I +V+D++N  SFE L+ W   ++ ++  +   PL  +VGN++
Sbjct: 178 GSDAIFIVFDVSNTPSFEALDSW---LREINRFATGSPLNVIVGNRV 309
>01398
          Length = 1421

 Score = 55.1 bits (131), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 32/95 (33%), Positives = 51/95 (53%)
 Frame = -2

Query: 82   YIYGAQGILLVYDITNYQSFENLEDWYSVVKTVSEESETQPLVALVGNKIDLEHMRTVKA 141
            Y   + G+++VYDIT   +FENL+ WY   +   E  +   LV  +G+K D E  R V A
Sbjct: 1390 YYRNSVGVIIVYDITKRSTFENLKQWYEEARNHIEPHKAIFLV--LGHKSDREDARQVTA 1217

Query: 142  DKHLRFCQENGFSSHFVSAKTGDSVFLCFQKVAAE 176
             +  RF + +G      SAK+G ++   F ++A +
Sbjct: 1216 REGRRFAEMHGLKFFETSAKSGHNIEDVFAQIAKD 1112
>13745
          Length = 1045

 Score = 55.1 bits (131), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 35/100 (35%), Positives = 55/100 (55%), Gaps = 3/100 (3%)
 Frame = +2

Query: 82  YIYGAQGILLVYDITNYQSFENLEDWYS--VVKTVSEESETQPLVALVGNKIDLEHMRTV 139
           +  GA   +LVYD+T   SF+NL+ W    +++    + E  P V L GNK+DL++ R V
Sbjct: 32  FYRGADCCVLVYDVTAPNSFKNLDSWRDEFLIQASPRDPEHFPFVVL-GNKVDLDN-RQV 205

Query: 140 KADKHLRFCQ-ENGFSSHFVSAKTGDSVFLCFQKVAAEIL 178
              +  ++CQ +N    +  SAK G +V + FQ +A   L
Sbjct: 206 STRRAQQWCQSKNDIPYYETSAKEGINVEMAFQTIAKNAL 325
>01972
          Length = 2359

 Score = 50.8 bits (120), Expect(2) = 4e-08,   Method: Compositional matrix adjust.
 Identities = 41/142 (28%), Positives = 75/142 (52%), Gaps = 1/142 (0%)
 Frame = +3

Query: 39  KQYKQTIGLDFF-LRRITLPGNLNVTLQVWDIGGQTIGGKMLDKYIYGAQGILLVYDITN 97
           K+Y  T+G++   L   T  G L     VWD  GQ   G + D Y    Q  ++++D+T+
Sbjct: 381 KKYVATLGVEVHPLLFHTSRGKLK--FNVWDTAGQEKFGGLRDGYYIQGQCAVIMFDVTS 554

Query: 98  YQSFENLEDWYSVVKTVSEESETQPLVALVGNKIDLEHMRTVKADKHLRFCQENGFSSHF 157
             +++N+ +W+   + +    E  P+V L GNK+D++  R VKA K + F ++     + 
Sbjct: 555 RVTYKNVPNWH---RDLVRVCENIPIV-LCGNKVDIKD-RKVKA-KAIVFHRKKNLQYYD 716

Query: 158 VSAKTGDSVFLCFQKVAAEILG 179
           +SAK+  +    F  +A +++G
Sbjct: 717 ISAKSNYNFEKPFLWLARKLVG 782

 Score = 23.5 bits (49), Expect(2) = 4e-08,   Method: Compositional matrix adjust.
 Identities = 9/26 (34%), Positives = 16/26 (61%)
 Frame = +1

Query: 4   SEEESQDRQLKIVVLGDGTSGKTSLA 29
           ++   Q+   K+V++GDG  GKT+  
Sbjct: 277 NQRMEQEPTFKLVLVGDGGVGKTTFV 354
>13750
          Length = 503

 Score = 53.1 bits (126), Expect = 8e-08,   Method: Compositional matrix adjust.
 Identities = 41/135 (30%), Positives = 62/135 (45%)
 Frame = -2

Query: 60  LNVTLQVWDIGGQTIGGKMLDKYIYGAQGILLVYDITNYQSFENLEDWYSVVKTVSEESE 119
           LNV   +WD GG      +   +  GAQ  LLVYD+T   SF       +V +    ++ 
Sbjct: 397 LNVRYTLWDTGGAETYRSLWVSHFRGAQVALLVYDVTCEWSFLTAT---TVWRKALMKNI 227

Query: 120 TQPLVALVGNKIDLEHMRTVKADKHLRFCQENGFSSHFVSAKTGDSVFLCFQKVAAEILG 179
            +  V  VG+K DLE  R +  ++   F  + G++    S+ TG +V   F ++A  IL 
Sbjct: 226 PEAQVIFVGSKTDLEENRVISTERGQAFATQCGYTFFETSSVTGKNVDAVFWEIAF-ILA 50

Query: 180 IKLNKAEIEQSQRVV 194
                A +E S   V
Sbjct: 49  RLQRSAHLELSMDTV 5
>07580
          Length = 921

 Score = 51.6 bits (122), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 49/162 (30%), Positives = 76/162 (46%), Gaps = 2/162 (1%)
 Frame = +3

Query: 37  FGKQYKQTIGLDFFLRRITLPGNLNVTLQVWDIGGQTIGGKMLDKYIYGAQGILLVYDIT 96
           F ++Y  TI  D + +++ + G     L++ D  G      M D Y+   QG LL Y IT
Sbjct: 135 FVEKYDPTIE-DSYRKQVEVDGQ-QCMLEILDTAGTEQFTAMRDLYMKNGQGFLLAYSIT 308

Query: 97  NYQSFENLEDWYSVVKTVSEESETQPLVALVGNKIDLEHMRTVKADKHLRFCQENGFSSH 156
              +F +L++    +  V +  +  P++ LVGNK DLE  R V  D+     +   FS  
Sbjct: 309 AQSTFNDLQELREQILRVKDTDDV-PML-LVGNKCDLEDERVVGKDQGQGLAR--SFSCA 476

Query: 157 FV--SAKTGDSVFLCFQKVAAEILGIKLNKAEIEQSQRVVKA 196
           F+  SAK   +V   F  +  +I     NK   EQS +  K+
Sbjct: 477 FLETSAKARINVNEIFMDLVRQI-----NKKSPEQSGKRTKS 587
>19006
          Length = 568

 Score = 51.6 bits (122), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 37/128 (28%), Positives = 60/128 (46%), Gaps = 1/128 (0%)
 Frame = -2

Query: 14  KIVVLGDGTSGKTSLATCFAQETFGKQYKQTIGLDFFLRRITLPGNLNVTLQVWDIGGQT 73
           K+V++GDG  GKT L   F+++ F + Y  T+  + ++  I +  +  V L +WD  GQ 
Sbjct: 432 KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTV-FENYVADIEV-DSKQVELALWDTAGQE 259

Query: 74  IGGKMLDKYIYGAQGILLVYDITNYQSFENL-EDWYSVVKTVSEESETQPLVALVGNKID 132
              ++          IL+ + I +  S EN+ E W   V+           + LVGNK D
Sbjct: 258 DYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVRHFCPNVP----IILVGNKKD 91

Query: 133 LEHMRTVK 140
           L +    K
Sbjct: 90  LRNDENTK 67
>12339
          Length = 578

 Score = 49.7 bits (117), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 39/130 (30%), Positives = 64/130 (49%), Gaps = 3/130 (2%)
 Frame = -2

Query: 82  YIYGAQGILLVYDITNYQSFENLEDWYS--VVKTVSEESETQPLVALVGNKIDLEHMRTV 139
           +  GA   +LVYD+T  ++F++L+ W    + +    + E  P V ++GNKIDL++ R V
Sbjct: 547 FYRGADCCILVYDVTEXKTFDSLDSWQREFLNQASPRDPEHFPFV-VIGNKIDLDN-RVV 374

Query: 140 KADKHLRFCQENGFSSHF-VSAKTGDSVFLCFQKVAAEILGIKLNKAEIEQSQRVVKADI 198
            A +   +C   G   +F  SAK   +V   FQ VA   L     ++E+E      +  +
Sbjct: 373 TAKRGQGWCSTKGGIPYFETSAKEAINVEQAFQTVAKNALA---QESEVEIDDFPSEIRL 203

Query: 199 VNYNQEPLSR 208
            N +  P  R
Sbjct: 202 SNDDSRPRER 173
>01095
          Length = 1745

 Score = 48.9 bits (115), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 33/114 (28%), Positives = 56/114 (49%), Gaps = 13/114 (11%)
 Frame = -1

Query: 91   LVYDITNYQSFENLEDWYSVVKTVSEESETQPLVALVGNKIDLEHMRTVKADKHLRFCQE 150
            +VYDITN  +F   + W   VK +  ++    ++AL GNK DL + R V+ ++   + +E
Sbjct: 1745 VVYDITNQDTFGRAKTW---VKELQRQASPNIVIALAGNKADLANKRMVEFEEAQAYAEE 1575

Query: 151  NGFSSHFVSAKTGDSVFLCFQKVAAEIL-------------GIKLNKAEIEQSQ 191
            N       SAKT  +V   F  +A ++              G++LN  + +QS+
Sbjct: 1574 NSLLFMETSAKTAMNVNDIFLAIAKKLPKNEGGGGSQPRQQGVRLNNEQSQQSE 1413
>24619
          Length = 509

 Score = 48.5 bits (114), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 23/66 (34%), Positives = 43/66 (65%)
 Frame = -2

Query: 78  MLDKYIYGAQGILLVYDITNYQSFENLEDWYSVVKTVSEESETQPLVALVGNKIDLEHMR 137
           M ++Y+    G LLV+ + +YQSFEN+ ++++ +  V ++ +T P++ L  NK+DL H R
Sbjct: 490 MREQYMRKGDGFLLVFSVIDYQSFENMVNFHTQILRV-KDRDTYPMI-LCANKVDLVHQR 317

Query: 138 TVKADK 143
            V  ++
Sbjct: 316 KVSEEQ 299
>11728
          Length = 635

 Score = 48.1 bits (113), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 35/124 (28%), Positives = 58/124 (46%), Gaps = 1/124 (0%)
 Frame = -1

Query: 11  RQLKIVVLGDGTSGKTSLATCFAQETFGKQYKQTIGLDFFLRRITLPGNLNVTLQVWDIG 70
           + +K VV+GDG  GKT L   +    F  +Y  T+  D +   + +  +  + L +WD  
Sbjct: 494 QAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTV-FDNYSANVMV-DSKPINLGLWDTA 321

Query: 71  GQTIGGKMLDKYIYGAQGILLVYDITNYQSFENLE-DWYSVVKTVSEESETQPLVALVGN 129
           GQ    ++           L+ + + +  SFEN++  WY     VS      P++ LVG 
Sbjct: 320 GQEDYDRLRPLSYPQTDVFLICFSLISPASFENVKAKWYP---EVSHHCPNTPII-LVGT 153

Query: 130 KIDL 133
           K+DL
Sbjct: 152 KLDL 141
>19046
          Length = 445

 Score = 47.8 bits (112), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 21/66 (31%), Positives = 44/66 (66%)
 Frame = -2

Query: 78  MLDKYIYGAQGILLVYDITNYQSFENLEDWYSVVKTVSEESETQPLVALVGNKIDLEHMR 137
           M ++Y+    G LLV+ +T+++SFEN+ ++++ +  V ++ ++ P++ L  NK+DL H R
Sbjct: 426 MREQYMRKGDGFLLVFSVTDFRSFENMANFHTQILRV-KDRDSYPMI-LCANKVDLVHQR 253

Query: 138 TVKADK 143
            V  ++
Sbjct: 252 KVSEEQ 235
>29380
          Length = 853

 Score = 46.6 bits (109), Expect = 9e-06,   Method: Compositional matrix adjust.
 Identities = 35/116 (30%), Positives = 54/116 (46%), Gaps = 11/116 (9%)
 Frame = -2

Query: 86  AQGILLVYDITNYQSFENLEDWYSVVKTVSEESETQPLVALVGNKIDLE-HMRTVKADKH 144
           A   ++VYD+    +F     W   VK + +++    L+ L GNK+DL    R V  +  
Sbjct: 852 ASAAIIVYDVNIADTFSRALAW---VKELRQQNTESVLIILAGNKVDLATQHRAVSFEDA 682

Query: 145 LRFCQENGFSSHFVSAKTGDSVFLCFQKVAAEIL----------GIKLNKAEIEQS 190
             F +ENG     VSAKTG +V   F  +A +++          G+ LN+   E S
Sbjct: 681 QSFARENGLLFAEVSAKTGMAVNEIFMTLANQLIQQEIDGSRNRGVTLNRENGEAS 514
>34359
          Length = 1042

 Score = 45.8 bits (107), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 29/103 (28%), Positives = 54/103 (52%)
 Frame = +3

Query: 39  KQYKQTIGLDFFLRRITLPGNLNVTLQVWDIGGQTIGGKMLDKYIYGAQGILLVYDITNY 98
           K+Y  T+G++    +      L +   VWD  GQ   G + D Y       ++++D+T+ 
Sbjct: 129 KKYVATLGVEVHPLQFNTSRGL-LRFNVWDTAGQEKFGGLRDGYYIQGTCAIIMFDVTSR 305

Query: 99  QSFENLEDWYSVVKTVSEESETQPLVALVGNKIDLEHMRTVKA 141
            +++N+ +W+   + +    E  P+V L GNK+D++  R VKA
Sbjct: 306 VTYKNVPNWH---RDLVRVCENIPIV-LCGNKVDIKD-RKVKA 419
>26536
          Length = 829

 Score = 44.3 bits (103), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 33/118 (27%), Positives = 51/118 (43%), Gaps = 1/118 (0%)
 Frame = +2

Query: 61  NVTLQVWDIGGQTIGGKMLDKYIYGAQGILLVYDITNYQSFENLEDWYSVVKTVSE-ESE 119
            V+    D  GQ     M + Y     G ++VY +T+  SF+  E   +V + ++  + E
Sbjct: 125 RVSWTFLDTAGQEEYSSMREHYTRSGDGFIVVYSVTDVTSFQEAE---AVFRWLTRFQDE 295

Query: 120 TQPLVALVGNKIDLEHMRTVKADKHLRFCQENGFSSHFVSAKTGDSVFLCFQKVAAEI 177
           T     L GNK DL   R V  ++  +     G      SAKTGD+V   +  +   I
Sbjct: 296 TSIHAVLCGNKTDLTSDRKVTPEEGRKMADRLGMLYFETSAKTGDNVSQVYHGLLRSI 469

 Score = 32.7 bits (73), Expect = 0.11,   Method: Compositional matrix adjust.
 Identities = 17/32 (53%), Positives = 20/32 (62%)
 Frame = +2

Query: 14  KIVVLGDGTSGKTSLATCFAQETFGKQYKQTI 45
           KIV+LG G  GK+SL   F Q+TF   Y  TI
Sbjct: 491 KIVMLGSGGVGKSSLTIRFTQDTFLDVYDPTI 586
>19656
          Length = 428

 Score = 44.3 bits (103), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 30/103 (29%), Positives = 46/103 (44%), Gaps = 1/103 (0%)
 Frame = +3

Query: 11  RQLKIVVLGDGTSGKTSLATCFAQETFGKQYKQTIGLDFFLRRITLPGNLNVTLQVWDIG 70
           + +K VV+GDG  GKT L   +    F  +Y  T+  D +   + + G   V L +WD  
Sbjct: 108 QAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTV-FDNYSANVMVDGR-PVNLGLWDTA 281

Query: 71  GQTIGGKMLDKYIYGAQGILLVYDITNYQSFENLE-DWYSVVK 112
           GQ    ++           LL + + +  SFEN+   WY  V 
Sbjct: 282 GQEDYDRLRPLSYPQTDVFLLCFSVASPASFENIRAKWYPEVN 410
>32723
          Length = 384

 Score = 44.3 bits (103), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 29/96 (30%), Positives = 45/96 (46%)
 Frame = +2

Query: 82  YIYGAQGILLVYDITNYQSFENLEDWYSVVKTVSEESETQPLVALVGNKIDLEHMRTVKA 141
           Y   A  ++LVYD+ + QS+E+L  W   +  +   + T+ L  LVGNKID    R +  
Sbjct: 32  YYRSANALILVYDVCSQQSYESLPQW---IHEIELYAGTKVLAFLVGNKIDQTDKREIPT 202

Query: 142 DKHLRFCQENGFSSHFVSAKTGDSVFLCFQKVAAEI 177
                F +         SAK  D+V   F  +A ++
Sbjct: 203 HIGKEFAERYEMRFLETSAKEADNVEKLFSTIAYQL 310
>00552
          Length = 455

 Score = 41.6 bits (96), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 20/50 (40%), Positives = 29/50 (58%)
 Frame = -1

Query: 9   QDRQLKIVVLGDGTSGKTSLATCFAQETFGKQYKQTIGLDFFLRRITLPG 58
           + R LK+V+LGDG  GK+SL   F    F  Q   TIG++F  + + + G
Sbjct: 455 KSRLLKVVLLGDGGVGKSSLMNRFVSNKFDAQSFHTIGVEFLTKDVVVDG 306

 Score = 32.3 bits (72), Expect = 0.15,   Method: Compositional matrix adjust.
 Identities = 13/43 (30%), Positives = 21/43 (48%)
 Frame = -3

Query: 66  VWDIGGQTIGGKMLDKYIYGAQGILLVYDITNYQSFENLEDWY 108
           +WD  GQ     +   +  G    LL + + N +S ++L DWY
Sbjct: 147 IWDTAGQERYKSLRTPFYRGTDCCLLTFSVDNLKSLQSLSDWY 19
>14119
          Length = 602

 Score = 41.2 bits (95), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 27/70 (38%), Positives = 39/70 (55%), Gaps = 2/70 (2%)
 Frame = +1

Query: 111 VKTVSEESETQPLVALVGNKIDL--EHMRTVKADKHLRFCQENGFSSHFVSAKTGDSVFL 168
           VK + +++    L+ L GNK DL  EH R V AD    F ++NG     VSAKTG +V  
Sbjct: 25  VKELRQQNAGSVLIVLAGNKADLASEH-RAVSADDARTFAEDNGLIFAEVSAKTGMAVSE 201

Query: 169 CFQKVAAEIL 178
            F  +A +++
Sbjct: 202 VFMTIAHKLV 231
>35581
          Length = 364

 Score = 40.8 bits (94), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 26/95 (27%), Positives = 40/95 (42%)
 Frame = +2

Query: 13  LKIVVLGDGTSGKTSLATCFAQETFGKQYKQTIGLDFFLRRITLPGNLNVTLQVWDIGGQ 72
            K V+LGD   GKT L    A + F      ++     L  +TL   +  ++ +WD  GQ
Sbjct: 47  FKCVLLGDAGVGKTCLLNRLATDKFLDSPLTSLTTASLLTTVTLTSGVMASVDLWDTAGQ 226

Query: 73  TIGGKMLDKYIYGAQGILLVYDITNYQSFENLEDW 107
                +   Y    + +L+VYD    +    L DW
Sbjct: 227 ERYRSLTSSYYRDTKAVLIVYDA---EHKLKLTDW 322
>25618
          Length = 475

 Score = 40.0 bits (92), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 27/71 (38%), Positives = 39/71 (54%), Gaps = 2/71 (2%)
 Frame = +3

Query: 110 VVKTVSEESETQPLVALVGNKIDL--EHMRTVKADKHLRFCQENGFSSHFVSAKTGDSVF 167
           V K + +++    L+ L GNK DL  EH R V AD    F ++NG     VSAKTG +V 
Sbjct: 42  VGKELRQQNAGSVLIVLAGNKADLASEH-RAVSADDARTFAEDNGLIFAEVSAKTGMAVS 218

Query: 168 LCFQKVAAEIL 178
             F  +A +++
Sbjct: 219 EVFMTIAHKLV 251
>08153
          Length = 1703

 Score = 36.2 bits (82), Expect = 0.012,   Method: Compositional matrix adjust.
 Identities = 31/160 (19%), Positives = 69/160 (43%), Gaps = 3/160 (1%)
 Frame = +1

Query: 11  RQLKIVVLGDGTSGKTSLATCFAQETFGKQYKQTIGLDFFLRRITLPGNLNVTLQVWDIG 70
           ++++I+++G   +GKT   T   +   G+       + F +  +      N++  VWD+G
Sbjct: 79  KEVRILMVGLDAAGKT---TILYKLKLGEIVTTIPTIGFNVETVEYK---NISFTVWDVG 240

Query: 71  GQTIGGKMLDKYIYGAQGILLVYDITNYQSFENLEDWYSVVKTVSEESETQPLVALVGNK 130
           GQ     +   Y    QG++ V D  + +     ++   + + ++E+     ++ +  NK
Sbjct: 241 GQDKIRPLWRHYFQNTQGLIFVVDSNDRERINEAKE--ELARMLNEDDLRDAIILVFANK 414

Query: 131 IDLEHMRTV-KADKHLRFCQENGFSSHF--VSAKTGDSVF 167
            DL +  +  +   HL      G   +     A +GD ++
Sbjct: 415 QDLPNAYSASEVTAHLGLANLKGRKWYMQATCATSGDGMY 534
>09827
          Length = 1201

 Score = 36.2 bits (82), Expect = 0.012,   Method: Compositional matrix adjust.
 Identities = 25/110 (22%), Positives = 49/110 (44%), Gaps = 3/110 (2%)
 Frame = -3

Query: 61  NVTLQVWDIGGQTIGGKMLDKYIYGAQGILLVYDITNYQSFENLEDWYSVVKTVSEESET 120
           N++  VWD+GGQ     +   Y    QG++ V D  + +  +   +   + + ++E+   
Sbjct: 986 NISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDKERVQEARE--ELTRMLNEDELR 813

Query: 121 QPLVALVGNKIDLEH-MRTVKADKHLRF--CQENGFSSHFVSAKTGDSVF 167
             ++ +  NK DL H M T +  + L     +   +      A TGD ++
Sbjct: 812 DAVLLVFANKQDLPHAMATAEITEKLGLHGLRNRTWYIQSTCATTGDGLY 663
>14775
          Length = 380

 Score = 34.3 bits (77), Expect = 0.042,   Method: Compositional matrix adjust.
 Identities = 16/37 (43%), Positives = 20/37 (54%)
 Frame = -2

Query: 60  LNVTLQVWDIGGQTIGGKMLDKYIYGAQGILLVYDIT 96
           LNV   +WD GG      +   +  GAQ  LLVYD+T
Sbjct: 274 LNVRYTLWDTGGAETYRSLWVSHFRGAQVALLVYDVT 164
>34597
          Length = 773

 Score = 34.3 bits (77), Expect = 0.045,   Method: Compositional matrix adjust.
 Identities = 27/107 (25%), Positives = 49/107 (45%)
 Frame = -2

Query: 99  QSFENLEDWYSVVKTVSEESETQPLVALVGNKIDLEHMRTVKADKHLRFCQENGFSSHFV 158
           +SFEN+  W   ++ + E +       ++GNK D+   R V  ++     +E+       
Sbjct: 712 KSFENIVKW---LRNIDEHANEDVEKMILGNKCDMTDKRVVSKERGEAIAREHSIRFMET 542

Query: 159 SAKTGDSVFLCFQKVAAEILGIKLNKAEIEQSQRVVKADIVNYNQEP 205
           SAK+  ++   F ++A  IL     +   E  +RVV  D  N ++ P
Sbjct: 541 SAKSNINIERAFCELAEAILDKTAGRESAENPERVV-IDRGNSDKAP 404
>18208
          Length = 458

 Score = 33.9 bits (76), Expect = 0.047,   Method: Compositional matrix adjust.
 Identities = 24/63 (38%), Positives = 33/63 (52%)
 Frame = -1

Query: 10  DRQLKIVVLGDGTSGKTSLATCFAQETFGKQYKQTIGLDFFLRRITLPGNLNVTLQVWDI 69
           DR+L+I++LG   +GKT+L    A E        T G  F ++ +   G     L VWDI
Sbjct: 308 DRELRILLLGLDNAGKTTLLKQLASED-PSHITPTQG--FNIKSVQSKG---FKLNVWDI 147

Query: 70  GGQ 72
           GGQ
Sbjct: 146 GGQ 138
>10862
          Length = 2896

 Score = 33.1 bits (74), Expect = 0.094,   Method: Compositional matrix adjust.
 Identities = 16/68 (23%), Positives = 30/68 (44%)
 Frame = -3

Query: 66   VWDIGGQTIGGKMLDKYIYGAQGILLVYDITNYQSFENLEDWYSVVKTVSEESETQPLVA 125
            VWD+GGQ     +   Y  G QG++ V D  +    +       + + +++      ++ 
Sbjct: 2474 VWDVGGQDKIRPLWRHYYTGTQGLIFVVDCADRDRIDEARQ--ELHRIINDREMRDAIIL 2301

Query: 126  LVGNKIDL 133
            +  NK DL
Sbjct: 2300 IFANKQDL 2277
>16653
          Length = 322

 Score = 30.0 bits (66), Expect = 0.69,   Method: Compositional matrix adjust.
 Identities = 16/52 (30%), Positives = 25/52 (48%), Gaps = 7/52 (13%)
 Frame = +1

Query: 158 VSAKTGDSVFLCFQKVAAEILGIKLNKAEIEQSQRVV-------KADIVNYN 202
           +S    D +F C+ K+   ILGI      IE+ +RV        K  ++NY+
Sbjct: 106 ISVIWFDHIFYCWNKMIISILGINEYTFYIERGRRVC**FA*LRKYHLINYH 261
>12440
          Length = 794

 Score = 28.5 bits (62), Expect = 2.4,   Method: Compositional matrix adjust.
 Identities = 13/44 (29%), Positives = 25/44 (56%)
 Frame = -1

Query: 104 LEDWYSVVKTVSEESETQPLVALVGNKIDLEHMRTVKADKHLRF 147
           LE W    + VS  ++ + +V+LVG+ +++ H+ +     H RF
Sbjct: 782 LETWSQNNRLVSIRADPRLVVSLVGDAVNMSHVSSPVTISHSRF 651
>33605
          Length = 888

 Score = 28.5 bits (62), Expect = 2.5,   Method: Compositional matrix adjust.
 Identities = 22/88 (25%), Positives = 42/88 (47%)
 Frame = +1

Query: 7   ESQDRQLKIVVLGDGTSGKTSLATCFAQETFGKQYKQTIGLDFFLRRITLPGNLNVTLQV 66
           + +++++++++LG   +GKT++   F  E        T+G  F ++ +   G     L V
Sbjct: 481 KQKEKEVRLLMLGLDNAGKTTILKKFNGEDI-DTISPTLG--FNIKTLEHRG---FKLNV 642

Query: 67  WDIGGQTIGGKMLDKYIYGAQGILLVYD 94
           WD+GGQ         Y     G++ V D
Sbjct: 643 WDVGGQQSLRSYWRNYFESTDGLVWVVD 726
>07059
          Length = 2866

 Score = 27.3 bits (59), Expect = 5.1,   Method: Compositional matrix adjust.
 Identities = 23/66 (34%), Positives = 31/66 (46%), Gaps = 11/66 (16%)
 Frame = +3

Query: 94  DITNYQSFEN--------LEDWYSVVKTVSE---ESETQPLVALVGNKIDLEHMRTVKAD 142
           DI N +S EN        L+D YS+  T+S     + T  L   + N I L H+RT    
Sbjct: 423 DIRNLKSSENSIRCTQIYLKDNYSLKLTLSCLKIVTHTHRLKINLKN*ICLNHIRTNIPQ 602

Query: 143 KHLRFC 148
            H+ FC
Sbjct: 603 AHIYFC 620
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|82883034|ref|XP_891381.1| PREDICTED: BAT2 domain
containing 1 isoform 2 [Mus musculus]
         (2846 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

39617                                                                  60   1e-16
03298                                                                  60   1e-08
12387                                                                  53   2e-06
35013                                                                  42   0.004
24047                                                                  36   0.022
33744                                                                  32   4.9  
>39617
          Length = 332

 Score = 60.5 bits (145), Expect(2) = 1e-16,   Method: Compositional matrix adjust.
 Identities = 34/64 (53%), Positives = 42/64 (65%), Gaps = 2/64 (3%)
 Frame = -1

Query: 1   MSEKSGQSTKAKDGK-KYATLSLFNTYKGKSLETQKTTVAARHGLQSLGKV-GISRRMPP 58
           MS  SG   K +  K K+  + +   Y+GKS+ETQK+TV  +HGLQSLGKV    RRMPP
Sbjct: 284 MSSISGLGAKGEKNKGKFKGIDINTIYRGKSVETQKSTVPRQHGLQSLGKVPSAPRRMPP 105

Query: 59  PANL 62
           PAN 
Sbjct: 104 PANF 93

 Score = 46.6 bits (109), Expect(2) = 1e-16,   Method: Compositional matrix adjust.
 Identities = 17/31 (54%), Positives = 27/31 (87%)
 Frame = -3

Query: 62 LPSLKAENKGNDPNVNIVPKDGTGWASKQEQ 92
           PSLK+E+ GNDP++++VP  G+GWASK+++
Sbjct: 96 FPSLKSEHSGNDPSISLVPAGGSGWASKEKE 4
>03298
          Length = 2006

 Score = 60.1 bits (144), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 37/74 (50%), Positives = 51/74 (68%), Gaps = 2/74 (2%)
 Frame = +3

Query: 1615 KVDALSQFDLNNYASVVIIDDHPEVTVIEDPQSNL-NDDGFTEVVSKKQQK-RLQDEERR 1672
            K DAL+  D+NNYASVV+IDD PEVT I+DP     ++DGF EV SKK  K +L+ E  +
Sbjct: 1665 KKDALANIDINNYASVVVIDDQPEVT-IDDPAFLFESNDGFQEVTSKKALKIKLKQEAEQ 1841

Query: 1673 KKEEQVVQVWSKKN 1686
            +K+    ++ S+KN
Sbjct: 1842 QKKLNSSRISSRKN 1883

 Score = 50.8 bits (120), Expect = 7e-06,   Method: Compositional matrix adjust.
 Identities = 32/67 (47%), Positives = 41/67 (61%)
 Frame = +2

Query: 1466 EEWETASESSDFNERRERDEKKNADKSSQAVVKAGESVLPPKREIAKRSFSSQRPGVDRQ 1525
            EEWETASE+SDF E+  RD K ++                 +R+ +K+SFS+QRP  DRQ
Sbjct: 1223 EEWETASENSDFLEK-GRDSKNDS--------------ADNRRDSSKKSFSNQRPFNDRQ 1357

Query: 1526 NRRGNNG 1532
            NRRG NG
Sbjct: 1358 NRRGGNG 1378
>12387
          Length = 1083

 Score = 52.8 bits (125), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 41/107 (38%), Positives = 55/107 (51%), Gaps = 12/107 (11%)
 Frame = +2

Query: 242 YRAMMPPYMFQQYP-RMAYPP-LHG-PMRFPPSL--------SEANKSLRGRGPPPSWAS 290
           YR +MP YMF + P    YPP   G P R+PP +            +   G         
Sbjct: 347 YRGIMPHYMFGRLPPGGGYPPNFPGFPPRYPPEVRFRSPMPPMPPQRQQEGD------DD 508

Query: 291 EPERPSILSASELKELDKFDNLDAE-ADEGWAGAQMEVDYTEQLNFS 336
            P+RP+I+S  +LKE D+   L +E  D GWAGAQ E+DY+ +L FS
Sbjct: 509 GPKRPAIVSEKDLKEFDEI--LRSETGDGGWAGAQGEIDYSAKLVFS 643

 Score = 33.1 bits (74), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 14/21 (66%), Positives = 17/21 (80%)
 Frame = +2

Query: 157 KEKEANDENYGPGPSLRPPNV 177
           KE+++ D  YGPGPSLRP NV
Sbjct: 2   KEEDSKDTQYGPGPSLRPQNV 64
>35013
          Length = 462

 Score = 42.0 bits (97), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 16/25 (64%), Positives = 19/25 (76%)
 Frame = +2

Query: 160 EANDENYGPGPSLRPPNVACWRDGG 184
           ++ D  YGPGPSLRP NV  WR+GG
Sbjct: 200 DSKDTQYGPGPSLRPQNVGSWREGG 274
>24047
          Length = 452

 Score = 36.2 bits (82), Expect(2) = 0.022,   Method: Compositional matrix adjust.
 Identities = 27/70 (38%), Positives = 38/70 (54%)
 Frame = +3

Query: 1451 KTPDLSNQNSSDQANEEWETASESSDFNERRERDEKKNADKSSQAVVKAGESVLPPKREI 1510
            K P L  Q S++   EEWETASE+SDF E+    +  +AD                +R+ 
Sbjct: 162  KKPPLQKQASNE--GEEWETASENSDFLEKGRDSKNDSADN---------------RRDS 290

Query: 1511 AKRSFSSQRP 1520
            +K+SFS+QRP
Sbjct: 291  SKKSFSNQRP 320

 Score = 21.9 bits (45), Expect(2) = 0.022,   Method: Compositional matrix adjust.
 Identities = 9/10 (90%), Positives = 9/10 (90%)
 Frame = +2

Query: 1523 DRQNRRGNNG 1532
            DRQNRRG NG
Sbjct: 329  DRQNRRGGNG 358
>33744
          Length = 511

 Score = 31.6 bits (70), Expect = 4.9,   Method: Compositional matrix adjust.
 Identities = 19/43 (44%), Positives = 24/43 (55%)
 Frame = -1

Query: 2371 GLSQPTSVQQIPIPIYAPLQGQHQAQLSLGAGPAVSQAQELFS 2413
            G SQP S  Q P+P +AP  G+H       +G  VSQA  L+S
Sbjct: 472  GNSQPASSSQNPVPRWAPGGGEHGQ-----SGSTVSQAPGLYS 359
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|92110037|ref|NP_064411.2| HLA-B associated transcript
2 [Mus musculus]
         (2158 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

39617                                                                  60   1e-16
12387                                                                  49   3e-05
35013                                                                  44   6e-04
03298                                                                  39   0.019
24047                                                                  32   2.1  
>39617
          Length = 332

 Score = 59.7 bits (143), Expect(2) = 1e-16,   Method: Compositional matrix adjust.
 Identities = 35/64 (54%), Positives = 43/64 (67%), Gaps = 2/64 (3%)
 Frame = -1

Query: 1   MSDRSGPTAKGKDGK-KYSSLNLFDTYKGKSLEIQKPAVAPRHGLQSLGKVAIA-RRMPP 58
           MS  SG  AKG+  K K+  +++   Y+GKS+E QK  V  +HGLQSLGKV  A RRMPP
Sbjct: 284 MSSISGLGAKGEKNKGKFKGIDINTIYRGKSVETQKSTVPRQHGLQSLGKVPSAPRRMPP 105

Query: 59  PANL 62
           PAN 
Sbjct: 104 PANF 93

 Score = 47.4 bits (111), Expect(2) = 1e-16,   Method: Compositional matrix adjust.
 Identities = 19/31 (61%), Positives = 27/31 (87%)
 Frame = -3

Query: 62 LPSLKAENKGNDPNVSLVPKDGTGWASKQEQ 92
           PSLK+E+ GNDP++SLVP  G+GWASK+++
Sbjct: 96 FPSLKSEHSGNDPSISLVPAGGSGWASKEKE 4
>12387
          Length = 1083

 Score = 48.5 bits (114), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 22/42 (52%), Positives = 30/42 (71%), Gaps = 2/42 (4%)
 Frame = +2

Query: 303 RPSILKEDNLKEFDQL--DQENDDGWAGAHEEVDYTEKLKFS 342
           RP+I+ E +LKEFD++   +  D GWAGA  E+DY+ KL FS
Sbjct: 518 RPAIVSEKDLKEFDEILRSETGDGGWAGAQGEIDYSAKLVFS 643

 Score = 29.3 bits (64), Expect(2) = 2.3,   Method: Compositional matrix adjust.
 Identities = 13/20 (65%), Positives = 15/20 (75%)
 Frame = +2

Query: 184 KERESAEQSSGPGPSLRPQN 203
           KE +S +   GPGPSLRPQN
Sbjct: 2   KEEDSKDTQYGPGPSLRPQN 61

 Score = 21.6 bits (44), Expect(2) = 2.3,   Method: Compositional matrix adjust.
 Identities = 7/9 (77%), Positives = 9/9 (100%)
 Frame = +1

Query: 206 TWRDGGGRG 214
           +WR+GGGRG
Sbjct: 67  SWREGGGRG 93
>35013
          Length = 462

 Score = 43.9 bits (102), Expect = 6e-04,   Method: Compositional matrix adjust.
 Identities = 31/78 (39%), Positives = 41/78 (52%)
 Frame = +2

Query: 137 SGVKSWAQASVTHGAHGDGGRASNLLSRFSREEFPTLQAAGDQDKAAKERESAEQSSGPG 196
           SG +SW+  +V   A G     S+   R  R+ F          +  KE +S +   GPG
Sbjct: 59  SGARSWSSVTVGSNAQGVL*VTSH---RHFRKSFHP*HQRKKGKETKKEEDSKDTQYGPG 229

Query: 197 PSLRPQNSTTWRDGGGRG 214
           PSLRPQN  +WR+GGGRG
Sbjct: 230 PSLRPQNVGSWREGGGRG 283
>03298
          Length = 2006

 Score = 39.3 bits (90), Expect = 0.019,   Method: Compositional matrix adjust.
 Identities = 33/93 (35%), Positives = 42/93 (45%)
 Frame = +2

Query: 1301 KSPDLSNQNSDQANEEWETASESSDFASERRGDKETPPAALMTSKXXXXXXXXXXXXXXX 1360
            K P L  Q S++  EEWETASE+SDF  + R                             
Sbjct: 1184 KKPPLQKQASNEG-EEWETASENSDFLEKGRD---------------------------- 1276

Query: 1361 ISAMSRGDLSQRAKDLSKRSFSSQRPGMDRQNR 1393
                S+ D +   +D SK+SFS+QRP  DRQNR
Sbjct: 1277 ----SKNDSADNRRDSSKKSFSNQRPFNDRQNR 1363
>24047
          Length = 452

 Score = 32.3 bits (72), Expect = 2.1,   Method: Compositional matrix adjust.
 Identities = 28/86 (32%), Positives = 37/86 (43%)
 Frame = +3

Query: 1301 KSPDLSNQNSDQANEEWETASESSDFASERRGDKETPPAALMTSKXXXXXXXXXXXXXXX 1360
            K P L  Q S++  EEWETASE+SDF  + R                             
Sbjct: 162  KKPPLQKQASNEG-EEWETASENSDFLEKGRD---------------------------- 254

Query: 1361 ISAMSRGDLSQRAKDLSKRSFSSQRP 1386
                S+ D +   +D SK+SFS+QRP
Sbjct: 255  ----SKNDSADNRRDSSKKSFSNQRP 320
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|30425330|ref|NP_780757.1| limbic system-associated
membrane protein [Mus musculus]
         (341 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

13135                                                                  82   2e-16
27666                                                                  63   2e-10
18345                                                                  55   3e-08
20110                                                                  51   5e-07
08294                                                                  43   2e-04
37675                                                                  42   3e-04
29990                                                                  42   4e-04
11855                                                                  39   0.002
19356                                                                  38   0.007
25455                                                                  37   0.010
38127                                                                  37   0.015
32888                                                                  31   0.017
17530                                                                  35   0.035
25766                                                                  29   0.038
06028                                                                  35   0.046
36498                                                                  32   0.057
07940                                                                  32   0.29 
35419                                                                  32   0.45 
34811                                                                  32   0.45 
12764                                                                  31   0.90 
32174                                                                  30   1.1  
29932                                                                  30   2.0  
09405                                                                  28   7.7  
>13135
          Length = 849

 Score = 82.4 bits (202), Expect = 2e-16,   Method: Compositional matrix adjust.
 Identities = 68/221 (30%), Positives = 105/221 (47%), Gaps = 20/221 (9%)
 Frame = -1

Query: 51  LRCVVEDK--NSKVAWLN---RSGI---IFAGHDKWSLDP-RVELEKRHALEYSLRIQKV 101
           L CVVE+K  + +V W+    R+G    I       S DP +  ++      + LRIQ  
Sbjct: 657 LXCVVENKPIDKEVQWVGTVVRNGTTRTIPVSIATRSYDPFKYSIDLPSPTSWRLRIQNG 478

Query: 102 DVYDEGSYTCSVQ--TQHEPKTSQVYLIVQVPPKISNI--SSDVTVNEGSNVTLVCMANG 157
            V DEG YTC VQ   Q+  K     +I+Q+P +IS++  SSDV+ +EG ++ L C A+G
Sbjct: 477 QVTDEGVYTCQVQLSNQNYAKAFHQLVIIQMP-QISDLDTSSDVSKSEGQSLVLRCHASG 301

Query: 158 RPEPVITWRHLTPXXXXXXXXXXXXXXXXITR---EQSGKYECKAANEVSSADVKQVKVT 214
           RP P + W  +                  I +   E +G Y+C ++N   S D + ++VT
Sbjct: 300 RPTPSVKWTRMAGELLPSGGREHLESDLVIPQLKPEHAGIYKCSSSNSAGS-DFRNIRVT 124

Query: 215 VNYPPTITESKS-NEATTGRQASLKCEASAVPAP---DFEW 251
           VN+ P ++ + +  +   G    L C     P P   D  W
Sbjct: 123 VNFAPVLSSANTVVQQAQGYVKELVCVVKGYPTPKADDITW 1

 Score = 38.9 bits (89), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 20/66 (30%), Positives = 30/66 (45%)
 Frame = -1

Query: 232 GRQASLKCEASAVPAPDFEWYRDDTRINSANGLEIKSTEGQSSLTVTNVTEEHYGNYTCV 291
           G+   L+C AS  P P  +W R    +  + G E      +S L +  +  EH G Y C 
Sbjct: 336 GQSLVLRCHASGRPTPSVKWTRMAGELLPSGGRE----HLESDLVIPQLKPEHAGIYKCS 169

Query: 292 AANKLG 297
           ++N  G
Sbjct: 168 SSNSAG 151
>27666
          Length = 873

 Score = 62.8 bits (151), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 56/202 (27%), Positives = 85/202 (42%), Gaps = 27/202 (13%)
 Frame = +1

Query: 46  GDTAILRCVVEDKNSK-VAWLNRSGIIFAGHDKWSLDPRVELEKRHA------------- 91
           G TA + C V +K +  V W+++        +  S+D  V L+                 
Sbjct: 205 GGTARINCTVANKQTNNVFWIHQDT-----GELISMDKAVTLQINQMIGGLRKFEIVQHG 369

Query: 92  ----LEYSLRIQKVDVYDEGSYTCSVQTQHEPKTSQVY----LIVQVPPKI--SNISSDV 141
               L ++L I+++   D G+Y C V+ Q+E   SQV     L VQVPPKI     ++ V
Sbjct: 370 PPDRLTFTLVIRRLRQQDAGTYVCQVKIQNENILSQVQKIGTLTVQVPPKIRPGETTTLV 549

Query: 142 TVNEGSNVTLVCMANGRPEPVITWRHLTPXXXXXXXXXXXXXXXXI---TREQSGKYECK 198
            +++  N +LVC + G P P ITW  L                  +   T +  G Y C 
Sbjct: 550 EIDQNQNSSLVCSSTGIPAPNITWTRLDGRALPTGYSQFRGRELPLNGATVDHMGVYRCV 729

Query: 199 AANEVSSADVKQVKVTVNYPPT 220
           A N +   D    +V V + PT
Sbjct: 730 ANNNIKPPDDHLCEVRVFHAPT 795

 Score = 49.7 bits (117), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 33/116 (28%), Positives = 55/116 (47%), Gaps = 6/116 (5%)
 Frame = +1

Query: 187 ITREQSGKYEC--KAANEVSSADVKQVK-VTVNYPPTITESKSN---EATTGRQASLKCE 240
           + ++ +G Y C  K  NE   + V+++  +TV  PP I   ++    E    + +SL C 
Sbjct: 409 LRQQDAGTYVCQVKIQNENILSQVQKIGTLTVQVPPKIRPGETTTLVEIDQNQNSSLVCS 588

Query: 241 ASAVPAPDFEWYRDDTRINSANGLEIKSTEGQSSLTVTNVTEEHYGNYTCVAANKL 296
           ++ +PAP+  W R D R       + +  E    L +   T +H G Y CVA N +
Sbjct: 589 STGIPAPNITWTRLDGRALPTGYSQFRGRE----LPLNGATVDHMGVYRCVANNNI 744
>18345
          Length = 461

 Score = 55.5 bits (132), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 42/133 (31%), Positives = 57/133 (42%), Gaps = 6/133 (4%)
 Frame = +1

Query: 95  SLRIQKVDVYDEGSYTCSVQTQHEPKTSQVYLIVQVPPKISNISSD-VTVNEGSNVTLVC 153
           +L I+ V + D G Y C + TQ         ++   P  +S  S D V++ EG   TLVC
Sbjct: 1   NLLIRHVRLNDTGVYECRINTQPSQIKQVTLVVQVPPVVLSEGSPDRVSLKEGDTATLVC 180

Query: 154 MANGRPEPVITW-----RHLTPXXXXXXXXXXXXXXXXITREQSGKYECKAANEVSSADV 208
              G P P +TW     R L                  +TR     YEC A N V  A  
Sbjct: 181 NVTGVPSPDVTWYKRNTRQLDAQKERVGSTGPVLVMYNVTRHCDDIYECYADNGVPPAVT 360

Query: 209 KQVKVTVNYPPTI 221
           K ++VTV+Y P +
Sbjct: 361 KAIRVTVDYAPEV 399

 Score = 40.0 bits (92), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 42/146 (28%), Positives = 65/146 (44%), Gaps = 5/146 (3%)
 Frame = +1

Query: 192 SGKYECKAANEVSSADVKQVKVTVNYPPTITESKSNEATT---GRQASLKCEASAVPAPD 248
           +G YEC+   + S   +KQV + V  PP +    S +  +   G  A+L C  + VP+PD
Sbjct: 34  TGVYECRINTQPSQ--IKQVTLVVQVPPVVLSEGSPDRVSLKEGDTATLVCNVTGVPSPD 207

Query: 249 FEWYRDDTRINSANGLEIKSTEGQSSLTVTNVTEEHYGNYTCVAANKL--GVTNASLVLF 306
             WY+ +TR   A    + ST     L + NVT      Y C A N +   VT A  V  
Sbjct: 208 VTWYKRNTRQLDAQKERVGST--GPVLVMYNVTRHCDDIYECYADNGVPPAVTKAIRVTV 381

Query: 307 SKYAKTEPDSMQVIEFLHIDLKSIRH 332
               +    + ++ + L  +   +RH
Sbjct: 382 DYAPEVHLPTKRIGQALAKNHLGLRH 459
>20110
          Length = 820

 Score = 51.2 bits (121), Expect = 5e-07,   Method: Compositional matrix adjust.
 Identities = 43/150 (28%), Positives = 66/150 (44%), Gaps = 13/150 (8%)
 Frame = -1

Query: 83  RVELEKRHALE---YSLRIQKVDVYDEGSYTCSVQ----TQHEPKTSQVYLIVQVPPKI- 134
           + E++KR + +   Y L ++++   D G YTC+V+    +  E  T    L VQVPP I 
Sbjct: 721 KYEVQKRLSGDRETYMLVVRRLVETDAGIYTCTVRITAVSYEEWPTKIGNLTVQVPPSIK 542

Query: 135 -SNISSDVTVNEGSNVTLVCMANGRPEPVITWRH----LTPXXXXXXXXXXXXXXXXITR 189
             + ++ + + +G N TLVC A+G P P ITW        P                  R
Sbjct: 541 PGDTTAVLQIEQGQNSTLVCAASGIPAPNITWTRSDGGFLPIGVAQFRSATLPMNNVTVR 362

Query: 190 EQSGKYECKAANEVSSADVKQVKVTVNYPP 219
           +  G Y C A N +        +V V + P
Sbjct: 361 DM-GVYRCVADNNIKPPAEHLAEVLVFHAP 275

 Score = 47.0 bits (110), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 32/111 (28%), Positives = 49/111 (44%), Gaps = 6/111 (5%)
 Frame = -1

Query: 192 SGKYECKAANEVSSADVKQVKV---TVNYPPTITESKSN---EATTGRQASLKCEASAVP 245
           +G Y C       S +    K+   TV  PP+I    +    +   G+ ++L C AS +P
Sbjct: 643 AGIYTCTVRITAVSYEEWPTKIGNLTVQVPPSIKPGDTTAVLQIEQGQNSTLVCAASGIP 464

Query: 246 APDFEWYRDDTRINSANGLEIKSTEGQSSLTVTNVTEEHYGNYTCVAANKL 296
           AP+  W R D         + +S    ++L + NVT    G Y CVA N +
Sbjct: 463 APNITWTRSDGGFLPIGVAQFRS----ATLPMNNVTVRDMGVYRCVADNNI 323
>08294
          Length = 1849

 Score = 43.1 bits (100), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 34/107 (31%), Positives = 45/107 (42%), Gaps = 4/107 (3%)
 Frame = +2

Query: 195 YECKAANEVSSADVKQVKVTVNYPPTITESKSNEATT--GRQASLKCEASAVPAPDFEWY 252
           Y C A +         + +++   P IT  KSN  T   G  A L C A   P+PD  WY
Sbjct: 5   YTCVATHPRQGVINATIHISIVEWPAIT-VKSNNITVFEGHSAILHCVAKGSPSPDIAWY 181

Query: 253 RDDTRI--NSANGLEIKSTEGQSSLTVTNVTEEHYGNYTCVAANKLG 297
           RD   I  N+      K+     ++ +  V  E  G Y CVA N  G
Sbjct: 182 RDSQPILPNARRYTLFKN----GTMKIRQVFMEDNGMYACVANNTAG 310

 Score = 34.7 bits (78), Expect = 0.060,   Method: Compositional matrix adjust.
 Identities = 24/85 (28%), Positives = 39/85 (45%), Gaps = 3/85 (3%)
 Frame = +2

Query: 38  TDNITVRQGDTAILRCVVEDKNS-KVAWLNRSGIIFAGHDKWSLDPRVELEKRHAL--EY 94
           ++NITV +G +AIL CV +   S  +AW   S             P +   +R+ L    
Sbjct: 95  SNNITVFEGHSAILHCVAKGSPSPDIAWYRDS------------QPILPNARRYTLFKNG 238

Query: 95  SLRIQKVDVYDEGSYTCSVQTQHEP 119
           +++I++V + D G Y C       P
Sbjct: 239 TMKIRQVFMEDNGMYACVANNTAGP 313

 Score = 33.9 bits (76), Expect = 0.092,   Method: Compositional matrix adjust.
 Identities = 33/126 (26%), Positives = 46/126 (36%), Gaps = 6/126 (4%)
 Frame = +2

Query: 132 PKISNISSDVTVNEGSNVTLVCMANGRPEPVITWRH-----LTPXXXXXXXXXXXXXXXX 186
           P I+  S+++TV EG +  L C+A G P P I W       L                  
Sbjct: 77  PAITVKSNNITVFEGHSAILHCVAKGSPSPDIAWYRDSQPILPNARRYTLFKNGTMKIRQ 256

Query: 187 ITREQSGKYECKAANEVSS-ADVKQVKVTVNYPPTITESKSNEATTGRQASLKCEASAVP 245
           +  E +G Y C A N     A      +      T+   +   +T  R +S  C A   P
Sbjct: 257 VFMEDNGMYACVANNTAGPLAGTSSFALR-----TMHWRRMKTSTW*RPSSSLCVA---P 412

Query: 246 APDFEW 251
           AP   W
Sbjct: 413 APTLPW 430
>37675
          Length = 741

 Score = 42.0 bits (97), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 30/103 (29%), Positives = 44/103 (42%), Gaps = 1/103 (0%)
 Frame = +2

Query: 195 YECKAANEVSSADVKQVKVTVNYPPTITESKSNEATTGR-QASLKCEASAVPAPDFEWYR 253
           Y C+ + + SS  V  +KV +  PP +  S  +     R  A +KC A  VP P   W  
Sbjct: 5   YSCEDSTDPSSLQVHALKVQM--PPVVKVSPHSLIYPARLNAKMKCHAEGVPKPTISWLF 178

Query: 254 DDTRINSANGLEIKSTEGQSSLTVTNVTEEHYGNYTCVAANKL 296
           ++  I S +            L V N  ++  G Y CVA  +L
Sbjct: 179 NNVPI-SEDPQHYDLESANELLVVYNAGDQDTGAYKCVARIRL 304

 Score = 32.0 bits (71), Expect = 0.33,   Method: Compositional matrix adjust.
 Identities = 19/59 (32%), Positives = 30/59 (50%), Gaps = 1/59 (1%)
 Frame = +2

Query: 108 SYTCSVQTQHEPKTSQVY-LIVQVPPKISNISSDVTVNEGSNVTLVCMANGRPEPVITW 165
           +Y+C   T  +P + QV+ L VQ+PP +      +      N  + C A G P+P I+W
Sbjct: 2   NYSCEDST--DPSSLQVHALKVQMPPVVKVSPHSLIYPARLNAKMKCHAEGVPKPTISW 172
>29990
          Length = 434

 Score = 41.6 bits (96), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 29/91 (31%), Positives = 43/91 (47%), Gaps = 8/91 (8%)
 Frame = +3

Query: 83  RVEL--EKRHALEY--SLRIQKVDVYDEGSYTCSVQ-TQHEPKTSQV---YLIVQVPPKI 134
           RVE+  + R +L +  +L I+     D G Y C  +    E  ++QV   Y   +V P  
Sbjct: 48  RVEISGDSRFSLLHDGTLMIEDAQDDDRGVYECIARNVAGETHSNQVELRYFGERVAPXF 227

Query: 135 SNISSDVTVNEGSNVTLVCMANGRPEPVITW 165
           +    D+   EG  V LVC A+G P P  +W
Sbjct: 228 TQRPQDIVTVEGQTVQLVCQASGHPRPTFSW 320

 Score = 36.2 bits (82), Expect = 0.018,   Method: Compositional matrix adjust.
 Identities = 28/114 (24%), Positives = 41/114 (35%), Gaps = 10/114 (8%)
 Frame = +3

Query: 157 GRPEPVITWRH------LTPXXXXXXXXXXXXXXXXITREQSGKYECKAANEVSSADVKQ 210
           G+P P I W H      ++                    +  G YEC A N        Q
Sbjct: 6   GKPVPEIVWMHNNNRVEISGDSRFSLLHDGTLMIEDAQDDDRGVYECIARNVAGETHSNQ 185

Query: 211 VKVTV---NYPPTITESKSNEATT-GRQASLKCEASAVPAPDFEWYRDDTRINS 260
           V++        P  T+   +  T  G+   L C+AS  P P F W R+  ++ S
Sbjct: 186 VELRYFGERVAPXFTQRPQDIVTVEGQTVQLVCQASGHPRPTFSWTRNLEQLGS 347
>11855
          Length = 1574

 Score = 39.3 bits (90), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 31/90 (34%), Positives = 37/90 (41%), Gaps = 7/90 (7%)
 Frame = +1

Query: 237 LKCEASAVPAPDFEWYRDDTRINSANGLEIKSTEGQSSLTVTN-------VTEEHYGNYT 289
           L C AS  P P   WY  D R NS     +    GQ S+ V            E+ G Y 
Sbjct: 373 LFCRASGYPEPTITWY--DGRNNS-----LPDNSGQFSIAVNGDLIIRDISWSENMGVYR 531

Query: 290 CVAANKLGVTNASLVLFSKYAKTEPDSMQV 319
           CVA N+LG  +    L+      EPDS  V
Sbjct: 532 CVAENELGSHSVQAFLYPT-TLDEPDSFPV 618

 Score = 37.4 bits (85), Expect = 0.009,   Method: Compositional matrix adjust.
 Identities = 47/167 (28%), Positives = 62/167 (37%), Gaps = 34/167 (20%)
 Frame = +1

Query: 105 DEGSYTCSVQTQHEPKTSQVYLIVQVPPKISNISSDVTVN-------------------- 144
           DEG YTC  +T  + +      IV+V  +  + S DVT                      
Sbjct: 181 DEGEYTCVAETPFKRRVQST--IVKVDTR--HYSPDVTCMSKRGSRGEPARVYMWTVSRL 348

Query: 145 --EGSNVTLVCMANGRPEPVITW---RHLTPXXXXXXXXXXXXXXXXIT----REQSGKY 195
             E + V L C A+G PEP ITW   R+ +                 I      E  G Y
Sbjct: 349 ELETTTVQLFCRASGYPEPTITWYDGRNNSLPDNSGQFSIAVNGDLIIRDISWSENMGVY 528

Query: 196 ECKAANEVSSADVKQVKVTVNYPPTITESKS-----NEATTGRQASL 237
            C A NE+ S  V+       YP T+ E  S     +  TTGR+  L
Sbjct: 529 RCVAENELGSHSVQAFL----YPTTLDEPDSFPV*THPMTTGREVLL 657
>19356
          Length = 451

 Score = 37.7 bits (86), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 22/91 (24%), Positives = 36/91 (39%), Gaps = 4/91 (4%)
 Frame = -2

Query: 218 PPTITESKSNEATTGRQASLKCEASAVPAPD----FEWYRDDTRINSANGLEIKSTEGQS 273
           PP   +            S+  E   +P  D     EW+++   +N+     I    G +
Sbjct: 285 PPQFVKPMPGLYNLQGGQSVHLETRVIPITDSSLVIEWFKNGRPLNNGCRFNIVFDRGFA 106

Query: 274 SLTVTNVTEEHYGNYTCVAANKLGVTNASLV 304
            L +  V  E  G+Y C A NK G   +++V
Sbjct: 105 ILDIIGVISEDTGDYFCFARNKAGQAQSNVV 13
>25455
          Length = 444

 Score = 37.4 bits (85), Expect = 0.010,   Method: Compositional matrix adjust.
 Identities = 27/111 (24%), Positives = 49/111 (44%), Gaps = 8/111 (7%)
 Frame = +1

Query: 195 YECKAANEVSSAD--VKQVKVTVNYPPT-ITESKSNEATTGRQASLKCEASAVPAPDFEW 251
           Y C A + V   +  +++++V V   P+ +   +  E   G  A + C A+A+P P   W
Sbjct: 1   YRCWAESTVHHINFPLREMRVVVQSAPSWVVAPQVTEVEVGETAEITCNATAIPDPVTNW 180

Query: 252 YRDDTRINSANGLEIKSTEGQSSLT-----VTNVTEEHYGNYTCVAANKLG 297
           + +   I+     +++   G+  LT     + NVT E      C   N+ G
Sbjct: 181 FVNGREISDVVEHDVRFQSGRFDLTSDRLILRNVTIEGRMVVQCNVTNRYG 333
>38127
          Length = 860

 Score = 36.6 bits (83), Expect = 0.015,   Method: Compositional matrix adjust.
 Identities = 32/118 (27%), Positives = 46/118 (38%), Gaps = 14/118 (11%)
 Frame = -1

Query: 189 REQSGKYECKAANEVSSADVKQ-VKVTVNY---PPTITESKSNEATTGRQASLKCEASAV 244
           R  +G Y C A  E   A VK  + V V +   P  +   KS          ++C+    
Sbjct: 776 RNFAGMYTCVA--EYEEAGVKSSISVDVPFYAHPKVLPFDKSKNLVQDESLVIECKVLGY 603

Query: 245 PAPDFEWYRDDTRI----------NSANGLEIKSTEGQSSLTVTNVTEEHYGNYTCVA 292
           P P   WY D+  I            AN  +  S EG + L +  V  +  G YTC++
Sbjct: 602 PKPVVSWYMDNVEIVDGADSRYSLKPANSYDGASIEG-AKLVIEEVQFDDAGEYTCMS 432

 Score = 27.3 bits (59), Expect = 8.7,   Method: Compositional matrix adjust.
 Identities = 16/63 (25%), Positives = 29/63 (46%), Gaps = 4/63 (6%)
 Frame = -1

Query: 107 GSYTCSVQTQHEPKTSQVYLIVQVP----PKISNISSDVTVNEGSNVTLVCMANGRPEPV 162
           G YTC    ++E    +  + V VP    PK+        + +  ++ + C   G P+PV
Sbjct: 764 GMYTCV--AEYEEAGVKSSISVDVPFYAHPKVLPFDKSKNLVQDESLVIECKVLGYPKPV 591

Query: 163 ITW 165
           ++W
Sbjct: 590 VSW 582
>32888
          Length = 418

 Score = 28.5 bits (62), Expect(2) = 0.017,   Method: Compositional matrix adjust.
 Identities = 15/39 (38%), Positives = 21/39 (53%), Gaps = 1/39 (2%)
 Frame = -3

Query: 232 GRQASLKCEASAVPAPDFEWYRDDTRI-NSANGLEIKST 269
           G+   L C A   P+P   WY++   I N  + +EIKST
Sbjct: 233 GQTVRLDCRAKGKPSPKVTWYKNGHIITNGDDRVEIKST 117

 Score = 26.6 bits (57), Expect(2) = 0.017,   Method: Compositional matrix adjust.
 Identities = 11/31 (35%), Positives = 19/31 (61%)
 Frame = -2

Query: 267 KSTEGQSSLTVTNVTEEHYGNYTCVAANKLG 297
           +S + +  LT+ ++  E  GNYTC+ +N  G
Sbjct: 138 QSGDQKYKLTIKSLGAEDKGNYTCIVSNTEG 46

 Score = 30.8 bits (68), Expect = 0.89,   Method: Compositional matrix adjust.
 Identities = 12/25 (48%), Positives = 15/25 (60%)
 Frame = -3

Query: 141 VTVNEGSNVTLVCMANGRPEPVITW 165
           V  +EG  V L C A G+P P +TW
Sbjct: 248 VLEDEGQTVRLDCRAKGKPSPKVTW 174
>17530
          Length = 503

 Score = 35.4 bits (80), Expect = 0.035,   Method: Compositional matrix adjust.
 Identities = 32/119 (26%), Positives = 54/119 (45%), Gaps = 14/119 (11%)
 Frame = +2

Query: 218 PPTITESKSNEATT-GRQASLKCEASAV-PAPDFEWYRDDTR-INSAN--GLEIKSTEGQ 272
           PP+IT   + +    G++    C +S   P P   W ++  + IN     G+   ST G 
Sbjct: 62  PPSITSDITGDVFEEGQRVRFTCSSSGGNPPPTITWTKNGVQLINGVQQIGVGQTSTSGG 241

Query: 273 SSLTVTNVT---EEHYGNYTCVAANKLGVTN---ASLVLFSKYAKT---EPDSMQVIEF 322
           S+    +V     +H  NYTC   N++ + +   AS+VL  +Y+     EP S  ++  
Sbjct: 242 STRNTVSVVMDHSDHQANYTCFVYNQVNINSSLTASVVLNVRYSPIITFEPFSPYIVRL 418

 Score = 32.3 bits (72), Expect = 0.26,   Method: Compositional matrix adjust.
 Identities = 21/59 (35%), Positives = 31/59 (52%), Gaps = 4/59 (6%)
 Frame = +2

Query: 111 CSVQTQHEPKTSQVYLIVQVPPKISNISSDVT---VNEGSNVTLVCMAN-GRPEPVITW 165
           C+VQ   +  ++   L V +PP   +I+SD+T     EG  V   C ++ G P P ITW
Sbjct: 2   CNVQ---DFGSASANLTVLLPPGPPSITSDITGDVFEEGQRVRFTCSSSGGNPPPTITW 169
>25766
          Length = 469

 Score = 29.3 bits (64), Expect(2) = 0.038,   Method: Compositional matrix adjust.
 Identities = 17/83 (20%), Positives = 34/83 (40%), Gaps = 3/83 (3%)
 Frame = +1

Query: 187 ITREQSGKYECKAANEVSSADVKQVKVTVNYPPTITESKSNE-ATTGRQASLKCEASAVP 245
           +T   +G+Y C   +           + ++ PP ++  + NE    G      C+ S  P
Sbjct: 82  VTAADAGRYRCVITSSEGITSEGFATLRISSPPVVSVKQRNENRQVGSSVKFHCDVSGDP 261

Query: 246 APDFEWYR--DDTRINSANGLEI 266
            P   W +  D+ + N+ + +E 
Sbjct: 262 VPQVRWEKKVDNCQRNTRSEMEF 330

 Score = 25.0 bits (53), Expect(2) = 0.038,   Method: Compositional matrix adjust.
 Identities = 10/24 (41%), Positives = 16/24 (66%)
 Frame = +3

Query: 275 LTVTNVTEEHYGNYTCVAANKLGV 298
           LT+ N+ +E  G Y C A+++ GV
Sbjct: 330 LTLYNIQKEDEGRYICTASSENGV 401
>06028
          Length = 1358

 Score = 35.0 bits (79), Expect = 0.046,   Method: Compositional matrix adjust.
 Identities = 15/48 (31%), Positives = 27/48 (56%)
 Frame = +1

Query: 250 EWYRDDTRINSANGLEIKSTEGQSSLTVTNVTEEHYGNYTCVAANKLG 297
           +W R+   ++  + ++  +  G  +L + N  EEH G YTC+A+N  G
Sbjct: 346 KWLRNRRPVDGPS-VQTFNERGIYTLAIMNAGEEHEGTYTCLASNAFG 486
>36498
          Length = 478

 Score = 29.3 bits (64), Expect(2) = 0.057,   Method: Compositional matrix adjust.
 Identities = 14/41 (34%), Positives = 21/41 (51%)
 Frame = +3

Query: 265 EIKSTEGQSSLTVTNVTEEHYGNYTCVAANKLGVTNASLVL 305
           E +   G + L    V+E   G Y CVA N+ G+T  ++ L
Sbjct: 201 EYEPAPGTAGLRFDPVSEGDAGRYVCVARNERGITEENVDL 323

 Score = 24.3 bits (51), Expect(2) = 0.057,   Method: Compositional matrix adjust.
 Identities = 12/44 (27%), Positives = 19/44 (43%), Gaps = 2/44 (4%)
 Frame = +1

Query: 212 KVTVNYPPTITESKSNE--ATTGRQASLKCEASAVPAPDFEWYR 253
            + +  PPT+T +      A  G +  ++C A   P P   W R
Sbjct: 31  SLVIQGPPTVTVTPGTRITALVGDRVDIECVAEGDPTPTVFWRR 162

 Score = 31.6 bits (70), Expect = 0.44,   Method: Compositional matrix adjust.
 Identities = 14/44 (31%), Positives = 24/44 (54%), Gaps = 1/44 (2%)
 Frame = +1

Query: 126 LIVQVPPKIS-NISSDVTVNEGSNVTLVCMANGRPEPVITWRHL 168
           L++Q PP ++    + +T   G  V + C+A G P P + WR +
Sbjct: 34  LVIQGPPTVTVTPGTRITALVGDRVDIECVAEGDPTPTVFWRRI 165
>07940
          Length = 1336

 Score = 32.3 bits (72), Expect = 0.29,   Method: Compositional matrix adjust.
 Identities = 17/42 (40%), Positives = 23/42 (54%), Gaps = 2/42 (4%)
 Frame = -3

Query: 275  LTVTNVTEEHYGNYTCVAANKLGVTNAS--LVLFSKYAKTEP 314
            L ++N+T E  G YTCV +N +GV   S  L +    A  EP
Sbjct: 1331 LIISNITVEDAGWYTCVVSNAIGVEYGSAWLTVVLDRADLEP 1206
>35419
          Length = 623

 Score = 31.6 bits (70), Expect = 0.45,   Method: Compositional matrix adjust.
 Identities = 23/92 (25%), Positives = 37/92 (40%), Gaps = 4/92 (4%)
 Frame = -2

Query: 228 EATTGRQASLKCEASAVPAP----DFEWYRDDTRINSANGLEIKSTEGQSSLTVTNVTEE 283
           E   G  A   C  +  P        +W +D+  I++     + +    +SLT++     
Sbjct: 544 EVNAGTDAKFTCSGTTDPEEVHMLKIKWMKDNKEISTVEQ-RMTTNIQDNSLTISGTIVR 368

Query: 284 HYGNYTCVAANKLGVTNASLVLFSKYAKTEPD 315
             G YTC++ N L    AS +L     K  PD
Sbjct: 367 DSGTYTCISTNGLDSAEASAML---TVKDRPD 281
>34811
          Length = 613

 Score = 31.6 bits (70), Expect = 0.45,   Method: Compositional matrix adjust.
 Identities = 13/40 (32%), Positives = 23/40 (57%)
 Frame = +3

Query: 126 LIVQVPPKISNISSDVTVNEGSNVTLVCMANGRPEPVITW 165
           ++ Q+P +I+      T++    +TL C   GRP+P+I W
Sbjct: 477 MLEQLPEEITR-----TISNTQPLTLTCRGQGRPQPIIEW 581

 Score = 28.5 bits (62), Expect = 4.0,   Method: Compositional matrix adjust.
 Identities = 14/44 (31%), Positives = 20/44 (45%)
 Frame = +3

Query: 212 KVTVNYPPTITESKSNEATTGRQASLKCEASAVPAPDFEWYRDD 255
           K+    P  IT + SN     +  +L C     P P  EW++DD
Sbjct: 474 KMLEQLPEEITRTISN----TQPLTLTCRGQGRPQPIIEWFKDD 593
>12764
          Length = 1055

 Score = 30.8 bits (68), Expect = 0.90,   Method: Compositional matrix adjust.
 Identities = 26/96 (27%), Positives = 43/96 (44%), Gaps = 4/96 (4%)
 Frame = +1

Query: 205 SADVKQV--KVTVNYPPTITES-KSNEATTGRQASLKCEASAVPAPDF-EWYRDDTRINS 260
           SAD  Q+  +++V YP T++ +  + +   G    L C     P P   EW ++      
Sbjct: 181 SADYCQMSPQISVQYPVTVSVTPDTQQREEGLNLDLTCITQGNPLPFLVEWRQEGENTTL 360

Query: 261 ANGLEIKSTEGQSSLTVTNVTEEHYGNYTCVAANKL 296
           A G         ++LT+TN++    G YTC   N +
Sbjct: 361 ATG---------NTLTLTNLSLSDTGTYTCTGYNTV 441
>32174
          Length = 293

 Score = 30.4 bits (67), Expect = 1.1,   Method: Composition-based stats.
 Identities = 10/32 (31%), Positives = 19/32 (59%)
 Frame = +2

Query: 34  FNRGTDNITVRQGDTAILRCVVEDKNSKVAWL 65
           F     N +V +G T +L+CV+ D+  ++ W+
Sbjct: 95  FQERPQNTSVIEGQTVVLKCVILDRVGRIQWV 190
>29932
          Length = 748

 Score = 29.6 bits (65), Expect = 2.0,   Method: Compositional matrix adjust.
 Identities = 28/108 (25%), Positives = 43/108 (39%), Gaps = 3/108 (2%)
 Frame = +3

Query: 193 GKYECKAANEVSSADVKQVKVTVNYP-PTIT--ESKSNEATTGRQASLKCEASAVPAPDF 249
           G+Y C A +   S     V+  V  P P IT   +   E    R   + C+ +     + 
Sbjct: 12  GQYRCNAIDPRGSIVTFVVRELVLLPLPQITFRPNIPLEVEADRNIEIYCDVTNARPENV 191

Query: 250 EWYRDDTRINSANGLEIKSTEGQSSLTVTNVTEEHYGNYTCVAANKLG 297
           +W  D+ R    +       +GQ  L    +T    G Y+C A+NK G
Sbjct: 192 QWATDNNRPLPGS----VHIDGQI-LRFVAITPADAGGYSCTASNKYG 320
>09405
          Length = 1043

 Score = 27.7 bits (60), Expect = 7.7,   Method: Compositional matrix adjust.
 Identities = 12/46 (26%), Positives = 24/46 (52%)
 Frame = -2

Query: 273 SSLTVTNVTEEHYGNYTCVAANKLGVTNASLVLFSKYAKTEPDSMQ 318
           ++LTV N+ ++ + N +CV A    + N ++ LF         S++
Sbjct: 178 TTLTVVNILKDPFLNCSCVLATLFAIFNVTVSLFCVLLFCNLCSLK 41
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6680744|ref|NP_031528.1| Na+/K+ -ATPase beta 3
subunit [Mus musculus]
         (278 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

06574                                                                  82   2e-16
13469                                                                  40   8e-04
12755                                                                  30   0.83 
10435                                                                  27   8.0  
12780                                                                  27   8.5  
11258                                                                  27   9.1  
>06574
          Length = 2012

 Score = 82.0 bits (201), Expect = 2e-16,   Method: Compositional matrix adjust.
 Identities = 77/293 (26%), Positives = 121/293 (41%), Gaps = 37/293 (12%)
 Frame = -3

Query: 19   FIYNPSSGEFLGRTSKSWGLILLFYLVFYGFLAALFTFTMWAMLQTLNDEVPKYRDQIP- 77
            F++N      LGR  +SW  I  FYL++Y  LA  F   +    QT++++ PK   +   
Sbjct: 1836 FLWNSEEKTVLGRGGRSWAEIGFFYLIYYICLAGFFVGMLAIFYQTVDEKRPKLTGESSL 1657

Query: 78   ---SPGLMVFPKPQTALEYTFSMSEPQTYKKLVEDLESFLKPY---SVEEQKNLTSCPDG 131
               +PG+   P P           +P +YK  V+ +   L+PY    V E K    C   
Sbjct: 1656 LKGNPGMGFQPIPDVEYTLVRFRRDPDSYKPHVKSISKILQPYLDAEVAEDKKGKVC-SA 1480

Query: 132  APFIQHGPDYRACQFPVSLLEECSGVTDANFGYSK-----GQPCILVKMNRIIDLIPDGY 186
                  G    AC+  V+ L +   + D  FGY++     GQPC+L+++N+I D +P+ Y
Sbjct: 1479 TDLPGEG---EACRVDVASLTQSCNI-DNKFGYNETSTLSGQPCVLLRLNKIFDWMPEKY 1312

Query: 187  P----QISCLPKEENATIATYPEFGVLD--------------LKYFP-------YYGKKR 221
                 + S   +E    I   PE   +D              ++Y+P       YY    
Sbjct: 1311 TKENIKNSGASEELQQKILDDPEMIYIDCVGENPADRDNIGPIQYYPEQGFRHYYYPFTN 1132

Query: 222  HVGYRQPLVAVQVKFDSGLNKKEVTVECHIAGTRNLKNKNERDKFLGRVSFKV 274
               Y  PLV VQ  F        + VEC         ++ E++   G V F++
Sbjct: 1131 QPDYMSPLVFVQ--FTKPAENVALMVECRALAPNINYDRTEKE---GGVHFEL 988
>13469
          Length = 521

 Score = 40.4 bits (93), Expect = 8e-04,   Method: Compositional matrix adjust.
 Identities = 45/177 (25%), Positives = 80/177 (45%), Gaps = 11/177 (6%)
 Frame = -1

Query: 7   KSFHQSLAEWKLFIYNPS-SGEF--LGRTSKSWGLILLFYLVFYGFLAALFTFTMWAMLQ 63
           K+F   + +WK ++      G    +GR+   W L++  YL F+  L  +F   M     
Sbjct: 521 KTFEDRIKQWKNWLLGTDYEGNVVCMGRSLMDWLLLIGGYLAFFSVLVVMFVVFMALFYW 342

Query: 64  TLNDEVPKYRDQ---IPSPGLMVFPKPQTALEYT-FSMSEPQTYKKLVEDLESFLKPYSV 119
            ++   P  ++    + +PG+   P+P        F   +  TY   ++ +E++LK Y  
Sbjct: 341 IIDWNFPTIQNPNSILQTPGIGFRPQPNIHNTIVRFVKGDGATYVHHLDHIEAYLKYYEN 162

Query: 120 EEQK--NLTSCPDGAPFIQHGPDY-RACQFP-VSLLEECSGVTDANFGYSKGQPCIL 172
           + Q+  N   C +     +   D  + C+F  ++L  +C  V   NFG+  GQPCIL
Sbjct: 161 QNQQGENYIDCNEIRE--RRTSDLNKVCRFDLINLGPDC--VKQQNFGFDDGQPCIL 3
>12755
          Length = 1062

 Score = 30.4 bits (67), Expect = 0.83,   Method: Compositional matrix adjust.
 Identities = 11/36 (30%), Positives = 21/36 (58%)
 Frame = +2

Query: 170 CILVKMNRIIDLIPDGYPQISCLPKEENATIATYPE 205
           C L+KM++I++ + +    + CLP+E    +   PE
Sbjct: 944 CFLLKMSKIVNFLAEQKKHVCCLPREITLFMILCPE 1051
>10435
          Length = 1164

 Score = 26.9 bits (58), Expect = 8.0,   Method: Compositional matrix adjust.
 Identities = 17/50 (34%), Positives = 24/50 (48%)
 Frame = +3

Query: 75  QIPSPGLMVFPKPQTALEYTFSMSEPQTYKKLVEDLESFLKPYSVEEQKN 124
           ++P+P L +F K      Y F  S  QTY       +S+L  Y  E+Q N
Sbjct: 3   KVPTPTLRIFQKQHKNHAYDFHPSTVQTYN--THTWKSYL*LY*EEKQXN 146
>12780
          Length = 598

 Score = 26.9 bits (58), Expect = 8.5,   Method: Compositional matrix adjust.
 Identities = 15/37 (40%), Positives = 17/37 (45%)
 Frame = -3

Query: 183 PDGYPQISCLPKEENATIATYPEFGVLDLKYFPYYGK 219
           PD  P I CLPK +N  +A    F     K  P  GK
Sbjct: 146 PDNNPVIDCLPKHKNIIVAA--GFSGHGFKLAPAVGK 42
>11258
          Length = 1044

 Score = 26.9 bits (58), Expect = 9.1,   Method: Compositional matrix adjust.
 Identities = 10/20 (50%), Positives = 14/20 (70%)
 Frame = +3

Query: 248 ECHIAGTRNLKNKNERDKFL 267
            CH+ G RNLKN ++R  F+
Sbjct: 798 HCHVLGHRNLKNPDDRCVFV 857
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|9790017|ref|NP_062740.1| prostaglandin E synthase 3
(cytosolic) [Mus musculus]
         (160 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

06220                                                                  81   2e-16
14232                                                                  73   5e-14
17525                                                                  40   3e-04
11395                                                                  28   1.5  
>06220
          Length = 1052

 Score = 81.3 bits (199), Expect = 2e-16,   Method: Compositional matrix adjust.
 Identities = 43/114 (37%), Positives = 63/114 (55%), Gaps = 1/114 (0%)
 Frame = -3

Query: 3   PASAKWYDRRDYVFIEFCVEDSKDVNVNFEKSKLTFSCLGGSDNFKHLNEIDLFHCIDPN 62
           PA   W  R+D V+I   +E+ KD      +   +F   GG++N KH  ++ LF  I P+
Sbjct: 975 PAPLLWAQRKDKVWITVVLENCKDGAHALTEQTFSFKGTGGTENLKHEVDLTLFGEIVPD 796

Query: 63  DSKHKRTDRSILCCLRKGES-GQSWPRLTKERAKLNWLSVDFNNWKDWEDDSDE 115
            S  +++DR     L K ++    WPRL KE+ KL++L  DFN WKD +D  DE
Sbjct: 795 KSTCQKSDRQAFYTLAKKDTDAPYWPRLIKEQKKLHYLKTDFNRWKDEDDSEDE 634
>14232
          Length = 930

 Score = 73.2 bits (178), Expect = 5e-14,   Method: Compositional matrix adjust.
 Identities = 36/95 (37%), Positives = 57/95 (60%), Gaps = 1/95 (1%)
 Frame = -1

Query: 21  VEDSKDVNVNFEKSKLTFSCLGGSDNFKHLNEIDLFHCIDPNDSKHKRTDR-SILCCLRK 79
           +E+    N+  ++  L FS  GG++N  H   +D F  I+P  S+H+  DR + L  ++ 
Sbjct: 927 LENCPHPNIELKEQSLHFSGKGGTENLAHDVTVDFFDKINPETSRHQSNDRHTTLVLMKA 748

Query: 80  GESGQSWPRLTKERAKLNWLSVDFNNWKDWEDDSD 114
            ++   WPRLTKE+ K +++  DFN WKD EDD+D
Sbjct: 747 DQTAPFWPRLTKEKIKCHYIKTDFNKWKD-EDDTD 646
>17525
          Length = 458

 Score = 40.4 bits (93), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 18/43 (41%), Positives = 31/43 (72%)
 Frame = -1

Query: 64  SKHKRTDRSILCCLRKGESGQSWPRLTKERAKLNWLSVDFNNW 106
           S+++RTD  +   ++K  S ++WPRLT++R KL WL +DF+ +
Sbjct: 245 SRYRRTDACVEFQIKKSVS-ETWPRLTEQRLKLPWLKIDFDKF 120
>11395
          Length = 1342

 Score = 28.1 bits (61), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 19/59 (32%), Positives = 28/59 (47%), Gaps = 2/59 (3%)
 Frame = +3

Query: 19   FCVEDSKDVNVNFEKSKLTFSCLGGSDNFKHLNEIDLFHCI--DPNDSKHKRTDRSILC 75
            +C+ DS    + F  S++T      +D  + +N  DLF  I  D N + H RT  S  C
Sbjct: 1044 YCITDSIPQGIGFVTSEVTPQSDTSADGKELVNAEDLFGAIGDDHNSNPHHRTLNSGKC 1220
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|225543103|ref|NP_780647.3| aldehyde dehydrogenase 4
family, member A1 [Mus musculus]
         (562 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

11245                                                                  83   3e-16
31624                                                                  74   2e-13
27685                                                                  62   5e-10
31982                                                                  50   2e-06
18652                                                                  40   0.002
01811                                                                  35   0.10 
25921                                                                  33   0.23 
>11245
          Length = 993

 Score = 82.8 bits (203), Expect = 3e-16,   Method: Compositional matrix adjust.
 Identities = 73/298 (24%), Positives = 126/298 (42%), Gaps = 2/298 (0%)
 Frame = +2

Query: 250 EAGLPPNIIQFVPADGPT-FGDTVTSSEHLCGINFTGSVPTFKHLWRQVAQNLDRFRTFP 308
           EAG+P  +I  V        G+    S  + GI+FTGS    K L+R  A  +       
Sbjct: 2   EAGIPRGVINVVTTKKAAPIGELFCKSPDVRGISFTGSTQVGKLLFRNCADGI------K 163

Query: 309 RLAGECGGKNFHFXXXXXXXXXXXXGTLRSAFEYGGQKCSACSRLYVPKSLWPQIKGRLL 368
           R+  E GG                 G + S F   GQ C + +R +V + ++ +   +L 
Sbjct: 164 RVCLELGGNAPFIVFDSANVEKAVDGAMASKFRNCGQTCVSANRFFVQEGVYDKFVSQLK 343

Query: 369 EEHSRIKVGDPAEDFGTFFSAVIDAKAFARIKKWLEHARSSPSLSILAGGQCNESVGYYV 428
           +    +K+GD  +        +I+   F ++  ++E ARS  +  I+ G    E    + 
Sbjct: 344 QRVEALKIGD-GKSSDVQIGPLINKMQFDKVSGFVEDARSKKANVIVGGKALQEFGSLFY 520

Query: 429 EPCIIESKDPQEPIMKEEIFGPVLTVYVYPDDKYRETLQLVDSTTSYGLTGAVFAQDKAI 488
            P I+    P   +  EE+FGPV+++  + D+      Q  D  T  GL G  ++ +   
Sbjct: 521 APTIVTDVPPSAQLYTEEVFGPVVSIIKFKDEA-EAVXQAND--TQRGLAGYFYSDN--- 682

Query: 489 VQEATRML-RNAAGNFYINDKSTGSVVGQQPFGGARASGTNDKPGGPHYILRWTSPQV 545
           +Q+  R+  R   G   +N+    +   + PFGG + SG   + G  H I  +   ++
Sbjct: 683 LQQVFRVAKRLEVGMVGVNEGIISAP--EAPFGGVKESGIG-REGSHHGIDDYVDIKI 847
>31624
          Length = 2324

 Score = 73.9 bits (180), Expect = 2e-13,   Method: Compositional matrix adjust.
 Identities = 82/316 (25%), Positives = 133/316 (42%), Gaps = 10/316 (3%)
 Frame = +1

Query: 196 YRGLEGFVAAISPFNFTA-IGGNLAGAPALMGNVVLWKPSDTAMLASYAVYRILREAGLP 254
           YR   G VA I+PFNF A I   +    A+ GN  + KPS+    A+  +  +L+EAG+P
Sbjct: 37  YRLPLGVVAGITPFNFPAMIPLWMFPMAAVCGNTCILKPSERDPGATMILMELLQEAGMP 216

Query: 255 PNIIQFVPA--DGPTFGDTVTSSEHLCGINFTGSVPTFKHLWRQVAQNLDRFRTFPRLAG 312
           P I+  +    D   F   +  +  +  I+F GS    ++++ + ++N  R +       
Sbjct: 217 PGIVNVIHGRHDSVNF---ICDNPDIKAISFVGSDQAGEYIYERGSKNGKRVQA------ 369

Query: 313 ECGGKNFHFXXXXXXXXXXXXGTLRSAFEYGGQKCSACSR-LYV--PKSLWPQIKGRLLE 369
             G KN                 + +AF   GQ+C A S  ++V   K   P+    L+E
Sbjct: 370 NMGAKNHGVIMPDANKESTLTQLVGAAFGAAGQRCMALSTAVFVGEAKKWIPE----LVE 537

Query: 370 EHSRIKVGDPAEDFGTFFSAVIDAKAFARIKKWLEHARSSPSLSILAGGQCNESVGY--- 426
               +KV    E  G     +I  ++  R+   ++ A       +L  G+  +  GY   
Sbjct: 538 RAKALKVTGGTEK-GADLGPLISPESKKRVCDLVQ-AGVDAGADLLLDGRGVQVPGYEKG 711

Query: 427 -YVEPCIIESKDPQEPIMKEEIFGPVLTVYVYPDDKYRETLQLVDSTTSYGLTGAVFAQD 485
            +V P I+   DP      EEIFGPVL       D   E + +V++   YG   A+F  +
Sbjct: 712 NFVGPTILHQVDPNMKCYTEEIFGPVLVSMEV--DTLDEAIDIVNA-NPYGNGTAIFTTN 882

Query: 486 KAIVQEATRMLRNAAG 501
                +    +R   G
Sbjct: 883 GGHGPQVHHGVRXGTG 930
>27685
          Length = 735

 Score = 62.4 bits (150), Expect = 5e-10,   Method: Compositional matrix adjust.
 Identities = 65/250 (26%), Positives = 103/250 (41%), Gaps = 1/250 (0%)
 Frame = +2

Query: 125 QVFLKAADMLSGPRRAEVLAKTMVGQGKTVIQAEIDAAAELIDFFRFNAKFAVELEGEQP 184
           QV  +AA ++   R  E+    ++  GK + +A  D      D  ++       L GE  
Sbjct: 2   QVLTRAAILIQ-EREEELARMEVLDTGKPIWEARYDIQG-CADTIQYYGGIVPTLVGEHT 175

Query: 185 ISVPPSTNHTVYRGLEGFVAAISPFNFTAIGGNLAGAPAL-MGNVVLWKPSDTAMLASYA 243
                S  +T+   L G V AI  +N+         +PAL  GN +++KPS    L +  
Sbjct: 176 KLSGGSFAYTLREPL-GVVGAIGAWNYPFQMAAWKSSPALACGNTMVFKPSPFTPLTAVM 352

Query: 244 VYRILREAGLPPNIIQFVPADGPTFGDTVTSSEHLCGINFTGSVPTFKHLWRQVAQNLDR 303
           +  I REAGLP      +  +G T G  ++  + +  ++FTGSV T   +    AQ +  
Sbjct: 353 LGEIYREAGLPDGCYNVIQGEGET-GQLISHHDDIAKMSFTGSVATGSKIMAACAQGIKH 529

Query: 304 FRTFPRLAGECGGKNFHFXXXXXXXXXXXXGTLRSAFEYGGQKCSACSRLYVPKSLWPQI 363
                    E GGK+               G + + F   GQ CS  +R++V +      
Sbjct: 530 VTL------ELGGKSPLIIFEDADLDNAVKGAMLANFLSQGQVCSNGTRVFVQRHC---- 679

Query: 364 KGRLLEEHSR 373
            G + E  SR
Sbjct: 680 -GEVCEASSR 706
>31982
          Length = 555

 Score = 50.1 bits (118), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 33/108 (30%), Positives = 55/108 (50%)
 Frame = +2

Query: 423 SVGYYVEPCIIESKDPQEPIMKEEIFGPVLTVYVYPDDKYRETLQLVDSTTSYGLTGAVF 482
           S G Y+ PCI+        +++EE+FG VL+V  +  D   E ++  +  T  GL G +F
Sbjct: 59  SGGIYLSPCILTGCHDDMTVVQEEVFGSVLSVLTF--DTQEEVVRRANB-TELGLAGGIF 229

Query: 483 AQDKAIVQEATRMLRNAAGNFYINDKSTGSVVGQQPFGGARASGTNDK 530
            +D     +  + L   AG+ YIN+ +   V    PFGG ++  ++ K
Sbjct: 230 TKDLKRAHQVAQQLE--AGSLYINNYNVYPV--GVPFGGYKSLASDVK 361
>18652
          Length = 759

 Score = 40.4 bits (93), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 32/117 (27%), Positives = 54/117 (46%), Gaps = 5/117 (4%)
 Frame = -1

Query: 417 GGQCNESVGYYVEPCIIESKDPQEPIMKEEIFGPVLTVYVYPDDKYRETLQLVDSTTSYG 476
           GG+  E  G +VEP II       P++  E F P+  VY        E +   ++    G
Sbjct: 585 GGKPIERPGNFVEPTIISGLSHDAPVVHRETFAPI--VYALKTTNLDEAIAW-NNEVKQG 415

Query: 477 LTGAVFAQDKAIVQEATRMLRNAAGNFYINDKSTGSVV-----GQQPFGGARASGTN 528
           LT ++F +D A V +      +  G   +N  ++G+ +     G++  GG R SG++
Sbjct: 414 LTSSLFTKDLANVFKWIGPKGSDCGIVNVNIPTSGAEIGGAFGGEKHTGGGRESGSD 244
>01811
          Length = 1288

 Score = 34.7 bits (78), Expect = 0.10,   Method: Compositional matrix adjust.
 Identities = 25/88 (28%), Positives = 42/88 (47%)
 Frame = +2

Query: 445 EEIFGPVLTVYVYPDDKYRETLQLVDSTTSYGLTGAVFAQDKAIVQEATRMLRNAAGNFY 504
           EE+FGP+L + V  D  + E +Q++ +     L   VF+ +  +V+  T    +++G   
Sbjct: 2   EEVFGPLLPIMVVKD--HHEAVQVI-TDKEKPLAMYVFSNNSDVVR--TLKEGSSSGAIL 166

Query: 505 INDKSTGSVVGQQPFGGARASGTNDKPG 532
           +ND      +   PFGG   SG     G
Sbjct: 167 VNDTIMHGGLCTLPFGGVGESGMGSYHG 250
>25921
          Length = 425

 Score = 33.5 bits (75), Expect = 0.23,   Method: Composition-based stats.
 Identities = 25/104 (24%), Positives = 42/104 (40%)
 Frame = +2

Query: 257 IIQFVPADGPTFGDTVTSSEHLCGINFTGSVPTFKHLWRQVAQNLDRFRTFPRLAGECGG 316
           +I  +   GPT G  ++    +  + FTGSV   + +    A++        R++ E GG
Sbjct: 2   VINVINGFGPTAGAAISEHPDINKVAFTGSVDVGRIIMEAAAKS-----NLKRISLELGG 166

Query: 317 KNFHFXXXXXXXXXXXXGTLRSAFEYGGQKCSACSRLYVPKSLW 360
           K+                   + F   GQ C A SR YV + ++
Sbjct: 167 KSPVVVFDDADIDFAVETXHEALFSNHGQSCCAGSRTYVHEKIY 298
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|23957688|ref|NP_082496.2| WD repeat domain 17 [Mus
musculus]
         (1273 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

30256                                                                  84   3e-16
27465                                                                  64   5e-10
01768                                                                  62   2e-09
03387                                                                  61   3e-09
02960                                                                  56   1e-07
13278                                                                  55   1e-07
01805                                                                  54   3e-07
19949                                                                  54   6e-07
19140                                                                  51   4e-06
12841                                                                  51   4e-06
17602                                                                  50   4e-06
26939                                                                  50   5e-06
12574                                                                  50   5e-06
16105                                                                  50   6e-06
13335                                                                  49   9e-06
01598                                                                  49   1e-05
12806                                                                  47   5e-05
10264                                                                  47   6e-05
20662                                                                  47   7e-05
27475                                                                  47   7e-05
02147                                                                  46   8e-05
29912                                                                  46   1e-04
04358                                                                  46   1e-04
06576                                                                  46   1e-04
37180                                                                  45   2e-04
03156                                                                  45   2e-04
00561                                                                  45   2e-04
25880                                                                  45   2e-04
01327                                                                  45   3e-04
31474                                                                  43   7e-04
12960                                                                  42   0.001
05393                                                                  42   0.002
17266                                                                  42   0.002
17598                                                                  42   0.002
27270                                                                  42   0.002
18981                                                                  41   0.002
34005                                                                  41   0.003
19498                                                                  40   0.005
21105                                                                  40   0.005
10162                                                                  40   0.006
33180                                                                  32   0.009
21921                                                                  39   0.010
00825                                                                  39   0.011
26107                                                                  38   0.022
25400                                                                  37   0.041
19863                                                                  37   0.051
27681                                                                  37   0.052
15745                                                                  37   0.060
21960                                                                  37   0.073
15780                                                                  36   0.11 
07781                                                                  36   0.12 
11915                                                                  35   0.18 
01557                                                                  35   0.24 
14500                                                                  35   0.24 
37142                                                                  34   0.29 
27806                                                                  34   0.30 
16199                                                                  34   0.32 
38362                                                                  34   0.40 
07741                                                                  34   0.48 
38039                                                                  34   0.49 
04395                                                                  33   0.50 
03395                                                                  33   0.66 
04524                                                                  33   0.72 
31054                                                                  33   0.95 
03044                                                                  33   1.1  
14105                                                                  32   1.1  
04088                                                                  32   1.3  
12140                                                                  31   2.7  
01462                                                                  29   2.9  
31384                                                                  31   3.6  
32214                                                                  31   3.7  
30295                                                                  30   4.3  
02090                                                                  30   4.4  
30428                                                                  30   4.4  
14555                                                                  30   5.9  
05642                                                                  30   6.5  
30297                                                                  30   6.9  
06338                                                                  30   8.7  
20271                                                                  29   9.4  
>30256
          Length = 961

 Score = 84.3 bits (207), Expect = 3e-16,   Method: Composition-based stats.
 Identities = 76/278 (27%), Positives = 119/278 (42%), Gaps = 2/278 (0%)
 Frame = +3

Query: 366 NVLATASFDGTIKVWDINTLTAVYTSPGNEGVIFALSWAPGDLNCIAGATSRNGAF-IWD 424
           N + + S D ++KVW+ +T    +T  G+   +  LS +   +  ++G  SR+    +WD
Sbjct: 75  NTVISGSTDRSLKVWNADTGVCTHTLYGHSSTVRCLSLSGKKV--VSG--SRDATLRVWD 242

Query: 425 IQKGKIIQRFNEHGKNGIFYIAWSHKDSKRIATCSGDGFCIIRTVDGKLLHKYKHPAAVF 484
           I+ G  +             +   H  + R         C+    DGK            
Sbjct: 243 IESGHCLN------------VLLGHMAAVR---------CV--QYDGK------------ 317

Query: 485 GCDWSQNNKDMIATGCEDKNIRVFYVATSSNQPLKVFSGHTARVFHVKWSPLREGI-LCS 543
                      + +G  D  +RV+   T+S   L    GHT RV+ +++    +G+ + S
Sbjct: 318 ----------RVVSGAXDYTVRVWDPDTASC--LHTLQGHTNRVYSLQF----DGVYVVS 449

Query: 544 GSDDGSVRIWDYTQDACVSTLNGHTAPVRGLMWNTEIPYLLISGSWDYTIKVWDTRGGVC 603
           GS D S+R+WD      V TL GH +   GL        LL+SG+ D T+KVWD   G C
Sbjct: 450 GSLDTSIRVWDVRCGKLVHTLMGHQSLTSGLELKDN---LLVSGNADSTVKVWDVHTGKC 620

Query: 604 LDTVYDHGADVYGLTCHPSRPFTMASCSRDSTVRLWSL 641
           L T+         +TC       + +CS D TV+LW L
Sbjct: 621 LQTLLGPNKHRSAVTCLQFNKKFVVTCSDDGTVKLWDL 734

 Score = 64.3 bits (155), Expect = 3e-10,   Method: Composition-based stats.
 Identities = 43/123 (34%), Positives = 63/123 (51%), Gaps = 1/123 (0%)
 Frame = +3

Query: 518 LKVFSGHTARVFHVKWSPLREG-ILCSGSDDGSVRIWDYTQDACVSTLNGHTAPVRGLMW 576
           +K   GHT  V    WS    G  + SGS D S+++W+     C  TL GH++ VR L  
Sbjct: 21  IKNLIGHTGGV----WSSQMTGNTVISGSTDRSLKVWNADTGVCTHTLYGHSSTVRCLSL 188

Query: 577 NTEIPYLLISGSWDYTIKVWDTRGGVCLDTVYDHGADVYGLTCHPSRPFTMASCSRDSTV 636
           + +    ++SGS D T++VWD   G CL+ +  H A V  +     R   + S + D TV
Sbjct: 189 SGK---KVVSGSRDATLRVWDIESGHCLNVLLGHMAAVRCVQYDGKR---VVSGAXDYTV 350

Query: 637 RLW 639
           R+W
Sbjct: 351 RVW 359

 Score = 54.7 bits (130), Expect = 2e-07,   Method: Composition-based stats.
 Identities = 30/83 (36%), Positives = 49/83 (59%), Gaps = 1/83 (1%)
 Frame = +3

Query: 560 CVSTLNGHTAPVRGLMWNTEIP-YLLISGSWDYTIKVWDTRGGVCLDTVYDHGADVYGLT 618
           C+  L GHT    G +W++++    +ISGS D ++KVW+   GVC  T+Y H + V  L+
Sbjct: 18  CIKNLIGHT----GGVWSSQMTGNTVISGSTDRSLKVWNADTGVCTHTLYGHSSTVRCLS 185

Query: 619 CHPSRPFTMASCSRDSTVRLWSL 641
               +   + S SRD+T+R+W +
Sbjct: 186 LSGKK---VVSGSRDATLRVWDI 245

 Score = 33.5 bits (75), Expect = 0.54,   Method: Composition-based stats.
 Identities = 22/57 (38%), Positives = 32/57 (56%), Gaps = 5/57 (8%)
 Frame = +3

Query: 368 LATASFDGTIKVWDINT---LTAVYTSP--GNEGVIFALSWAPGDLNCIAGATSRNG 419
           + T S DGT+K+WD+NT   +  + T P  G+ GV++ L      + C  G  SRNG
Sbjct: 690 VVTCSDDGTVKLWDLNTGDFIRNLITLPSGGSGGVVWRLRCNNTKMVCAVG--SRNG 854

 Score = 30.0 bits (66), Expect = 6.8,   Method: Composition-based stats.
 Identities = 48/249 (19%), Positives = 91/249 (36%), Gaps = 7/249 (2%)
 Frame = +3

Query: 218 ITTFNLPSAAVSVQCLAWVPSAPGMFITGDSQVGVLRIWNVSRTTPIDNFKLKKTGFHCF 277
           + T  L   + +V+CL    S  G  +   S+   LR+W++     ++          C 
Sbjct: 135 VCTHTLYGHSSTVRCL----SLSGKKVVSGSRDATLRVWDIESGHCLNVLLGHMAAVRCV 302

Query: 278 H-----VVNSPPKKKFSVQSPNKNHYISSTSEAVPPPNLTQNQAFSLPPG--HVVCCFLD 330
                 VV+        V  P+       T+  +       N+ +SL     +VV   LD
Sbjct: 303 QYDGKRVVSGAXDYTVRVWDPD-------TASCLHTLQGHTNRVYSLQFDGVYVVSGSLD 461

Query: 331 GGVGLYDMGAKKWDFLRELGHVETIFDCKFKPDDPNVLATASFDGTIKVWDINTLTAVYT 390
             + ++D+   K      +GH       + K    N+L + + D T+KVWD++T   + T
Sbjct: 462 TSIRVWDVRCGKL-VHTLMGHQSLTSGLELKD---NLLVSGNADSTVKVWDVHTGKCLQT 629

Query: 391 SPGNEGVIFALSWAPGDLNCIAGATSRNGAFIWDIQKGKIIQRFNEHGKNGIFYIAWSHK 450
             G      A++    +   +   +      +WD+  G  I+        G   + W  +
Sbjct: 630 LLGPNKHRSAVTCLQFNKKFVVTCSDDGTVKLWDLNTGDFIRNLITLPSGGSGGVVWRLR 809

Query: 451 DSKRIATCS 459
            +     C+
Sbjct: 810 CNNTKMVCA 836
>27465
          Length = 658

 Score = 63.5 bits (153), Expect = 5e-10,   Method: Compositional matrix adjust.
 Identities = 42/157 (26%), Positives = 76/157 (48%), Gaps = 8/157 (5%)
 Frame = -1

Query: 493 KDMIATGCEDKNIRVFYVATSSNQP--------LKVFSGHTARVFHVKWSPLREGILCSG 544
           K+ + T  + ++++ +  A    +P         KV   H   + +V ++      + +G
Sbjct: 481 KEQLITPSKQEHVKNWCFACRKTRPKDDHHFYLFKVLRAHILPLTNVAFNKSGSSFI-TG 305

Query: 545 SDDGSVRIWDYTQDACVSTLNGHTAPVRGLMWNTEIPYLLISGSWDYTIKVWDTRGGVCL 604
           S D + +IWD      + TL GH   V  + +N      +I+GS+D T K+W T  G C 
Sbjct: 304 SYDRTCKIWDTASAEELHTLEGHRNVVYAIAFNNPFGDKVITGSFDKTCKLWSTADGKCY 125

Query: 605 DTVYDHGADVYGLTCHPSRPFTMASCSRDSTVRLWSL 641
            T+  H A++  ++ +PS    +A+ S D+T RLW +
Sbjct: 124 HTLRGHTAEIVCVSFNPSSTL-IATGSMDTTCRLWDV 17

 Score = 37.4 bits (85), Expect = 0.035,   Method: Compositional matrix adjust.
 Identities = 28/103 (27%), Positives = 42/103 (40%), Gaps = 6/103 (5%)
 Frame = -1

Query: 333 VGLYDMGAKKWDFL--REL----GHVETIFDCKFKPDDPNVLATASFDGTIKVWDINTLT 386
            G YD   K WD     EL    GH   ++   F     + + T SFD T K+W      
Sbjct: 310 TGSYDRTCKIWDTASAEELHTLEGHRNVVYAIAFNNPFGDKVITGSFDKTCKLWSTADGK 131

Query: 387 AVYTSPGNEGVIFALSWAPGDLNCIAGATSRNGAFIWDIQKGK 429
             +T  G+   I  +S+ P     IA  +      +WD++K +
Sbjct: 130 CYHTLRGHTAEIVCVSFNPSS-TLIATGSMDTTCRLWDVEKAQ 5

 Score = 34.7 bits (78), Expect = 0.25,   Method: Compositional matrix adjust.
 Identities = 28/101 (27%), Positives = 45/101 (44%), Gaps = 1/101 (0%)
 Frame = -1

Query: 411 IAGATSRNGAFIWDIQKGKIIQRFNEHGKNGIFYIAWSHKDSKRIATCSGDGFCII-RTV 469
           I G+  R    IWD    + +     H +N ++ IA+++    ++ T S D  C +  T 
Sbjct: 313 ITGSYDRTCK-IWDTASAEELHTLEGH-RNVVYAIAFNNPFGDKVITGSFDKTCKLWSTA 140

Query: 470 DGKLLHKYKHPAAVFGCDWSQNNKDMIATGCEDKNIRVFYV 510
           DGK  H  +   A   C     +  +IATG  D   R++ V
Sbjct: 139 DGKCYHTLRGHTAEIVCVSFNPSSTLIATGSMDTTCRLWDV 17

 Score = 33.1 bits (74), Expect = 0.76,   Method: Compositional matrix adjust.
 Identities = 27/102 (26%), Positives = 47/102 (46%), Gaps = 1/102 (0%)
 Frame = -1

Query: 370 TASFDGTIKVWDINTLTAVYTSPGNEGVIFALSW-APGDLNCIAGATSRNGAFIWDIQKG 428
           T S+D T K+WD  +   ++T  G+  V++A+++  P     I G+  +    +W    G
Sbjct: 310 TGSYDRTCKIWDTASAEELHTLEGHRNVVYAIAFNNPFGDKVITGSFDKTCK-LWSTADG 134

Query: 429 KIIQRFNEHGKNGIFYIAWSHKDSKRIATCSGDGFCIIRTVD 470
           K       H    I  ++++   S  IAT S D  C +  V+
Sbjct: 133 KCYHTLRGHTAE-IVCVSFN-PSSTLIATGSMDTTCRLWDVE 14
>01768
          Length = 1424

 Score = 62.0 bits (149), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 49/187 (26%), Positives = 81/187 (43%), Gaps = 12/187 (6%)
 Frame = +3

Query: 423 WDIQKGKIIQRFNEHGKNGIFYIAWSHKDSKRIAT--CSGDGFCIIRTVDGKLLHKYK-- 478
           +D  +  I+     H   G F I WS      + T  C+G  +    +  G    K    
Sbjct: 654 YDSTQKSIVHTVTHHTTEG-FAIDWSPAAKGWLVTGDCTGAIYISQPSSSGWTTEKSSYA 830

Query: 479 -HPAAVFGCDWSQNNKDMIATGCEDKNIRVFYVAT--SSNQPLKVFSGHTARVFHVKWSP 535
            H  +V    WS N  ++ A+   D+ +R++      S    L V   H+  +  + W+P
Sbjct: 831 AHTDSVEDVQWSPNEGNVFASCSVDRTLRIWNTQQKPSKANVLTVPEAHSRDINVINWNP 1010

Query: 536 LREGILCSGSDDGSVRIWDYT--QDACVS---TLNGHTAPVRGLMWNTEIPYLLISGSWD 590
           + + +L SG DDG ++IWD    ++  VS   +   H+ PV  L WN +   +L +   D
Sbjct: 1011IEKHLLASGGDDGIIKIWDLRMFRNKPVSAQASFKLHSQPVTSLEWNPQDSSVLAASGED 1190

Query: 591 YTIKVWD 597
             I +WD
Sbjct: 1191DQITIWD 1211

 Score = 57.4 bits (137), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 46/173 (26%), Positives = 70/173 (40%), Gaps = 10/173 (5%)
 Frame = +3

Query: 479 HPAAVFGCDWSQNNKDMIATGCEDKNIRVFYVATSSNQPLKV-FSGHTARVFHVKWSPLR 537
           H    F  DWS   K  + TG     I +   ++S     K  ++ HT  V  V+WSP  
Sbjct: 696 HTTEGFAIDWSPAAKGWLVTGDCTGAIYISQPSSSGWTTEKSSYAAHTDSVEDVQWSPNE 875

Query: 538 EGILCSGSDDGSVRIWDYTQDACVSTL----NGHTAPVRGLMWNTEIPYLLISGSWDYTI 593
             +  S S D ++RIW+  Q    + +      H+  +  + WN    +LL SG  D  I
Sbjct: 876 GNVFASCSVDRTLRIWNTQQKPSKANVLTVPEAHSRDINVINWNPIEKHLLASGGDDGII 1055

Query: 594 KVWDTR----GGVCLDTVYD-HGADVYGLTCHPSRPFTMASCSRDSTVRLWSL 641
           K+WD R      V     +  H   V  L  +P     +A+   D  + +W  
Sbjct: 1056KIWDLRMFRNKPVSAQASFKLHSQPVTSLEWNPQDSSVLAASGEDDQITIWDF 1214

 Score = 46.6 bits (109), Expect = 6e-05,   Method: Compositional matrix adjust.
 Identities = 51/247 (20%), Positives = 95/247 (38%), Gaps = 29/247 (11%)
 Frame = +3

Query: 369 ATASFDGTIKVWDINTLTAVYTSPGNEGVIFALSWAPGDLNCIAGATSRNGAFI------ 422
           A   +D T K     ++    T    EG  FA+ W+P     +         +I      
Sbjct: 642 AAGKYDSTQK-----SIVHTVTHHTTEG--FAIDWSPAAKGWLVTGDCTGAIYISQPSSS 800

Query: 423 -WDIQKGKIIQRFNEHGKNGIFYIAWSHKDSKRIATCSGDGFCIIRTVDGK------LLH 475
            W  +K      +  H  + +  + WS  +    A+CS D    I     K      L  
Sbjct: 801 GWTTEKSS----YAAH-TDSVEDVQWSPNEGNVFASCSVDRTLRIWNTQQKPSKANVLTV 965

Query: 476 KYKHPAAVFGCDWSQNNKDMIATGCEDKNIRVFYVATSSNQPLKV---FSGHTARVFHVK 532
              H   +   +W+   K ++A+G +D  I+++ +    N+P+     F  H+  V  ++
Sbjct: 966 PEAHSRDINVINWNPIEKHLLASGGDDGIIKIWDLRMFRNKPVSAQASFKLHSQPVTSLE 1145

Query: 533 WSPLREGILCSGSDDGSVRIWDYTQ-----------DACVSTLNGH--TAPVRGLMWNTE 579
           W+P    +L +  +D  + IWD++            D     L  H     ++ + W+ +
Sbjct: 1146WNPQDSSVLAASGEDDQITIWDFSVERDEGEGEEELDVPAQLLFQHCGQTDIKEVHWHPQ 1325

Query: 580 IPYLLIS 586
           +P +LIS
Sbjct: 1326LPGVLIS 1346

 Score = 39.7 bits (91), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 48/224 (21%), Positives = 76/224 (33%), Gaps = 27/224 (12%)
 Frame = +3

Query: 58   HKKTITAISWCPHNPDLFASSSTDNLVIIWNVAEQKVIAKLDNIKETPACLGWCWNTHDA 117
            H  ++  + W P+  ++FAS S D  + IWN  ++   A   N+   P            
Sbjct: 834  HTDSVEDVQWSPNEGNVFASCSVDRTLRIWNTQQKPSKA---NVLTVP------------ 968

Query: 118  VAFVSQKGPLLIWTISGPDSGVSVHKEAHSFASDICIFRWHTQKKGKVAFGHIDGSISIF 177
                                      EAHS   DI +  W+  +K  +A G  DG I I+
Sbjct: 969  --------------------------EAHS--RDINVINWNPIEKHLLASGGDDGIIKIW 1064

Query: 178  QPD---------------EEDPVTALEWDPLSTDYLLVANLHFGIRLLD----SESLYCI 218
                                 PVT+LEW+P  +  L  +     I + D     +     
Sbjct: 1065 DLRMFRNKPVSAQASFKLHSQPVTSLEWNPQDSSVLAASGEDDQITIWDFSVERDEGEGE 1244

Query: 219  TTFNLPSAAVSVQC-------LAWVPSAPGMFI-TGDSQVGVLR 254
               ++P+  +   C       + W P  PG+ I T  S   + R
Sbjct: 1245 EELDVPAQLLFQHCGQTDIKEVHWHPQLPGVLISTAKSDFNIFR 1376

 Score = 33.5 bits (75), Expect = 0.55,   Method: Compositional matrix adjust.
 Identities = 25/114 (21%), Positives = 47/114 (41%), Gaps = 6/114 (5%)
 Frame = +3

Query: 26  GDRFAYCAT-LAIYIYQLDHRYNEFKLHAIMSEHKKTITAISWCPHNPDLFASSSTDNLV 84
           G+ FA C+    + I+    + ++  +  +   H + I  I+W P    L AS   D ++
Sbjct: 876 GNVFASCSVDRTLRIWNTQQKPSKANVLTVPEAHSRDINVINWNPIEKHLLASGGDDGII 1055

Query: 85  IIWNV---AEQKVIAKLDNIKETPACLGWCWNTHDA--VAFVSQKGPLLIWTIS 133
            IW++     + V A+      +       WN  D+  +A   +   + IW  S
Sbjct: 1056KIWDLRMFRNKPVSAQASFKLHSQPVTSLEWNPQDSSVLAASGEDDQITIWDFS 1217

 Score = 30.8 bits (68), Expect = 3.8,   Method: Compositional matrix adjust.
 Identities = 27/104 (25%), Positives = 44/104 (42%), Gaps = 3/104 (2%)
 Frame = +3

Query: 553 WDYTQDACVSTLNGHTAPVRGLMWNTEIPYLLISGSWDYTIKVWD--TRGGVCLDTVYD- 609
           +D TQ + V T+  HT     + W+      L++G     I +    + G     + Y  
Sbjct: 654 YDSTQKSIVHTVTHHTTEGFAIDWSPAAKGWLVTGDCTGAIYISQPSSSGWTTEKSSYAA 833

Query: 610 HGADVYGLTCHPSRPFTMASCSRDSTVRLWSLIPLITPLQINIL 653
           H   V  +   P+     ASCS D T+R+W+      P + N+L
Sbjct: 834 HTDSVEDVQWSPNEGNVFASCSVDRTLRIWNTQQ--KPSKANVL 959
>03387
          Length = 1891

 Score = 61.2 bits (147), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 50/184 (27%), Positives = 74/184 (40%), Gaps = 18/184 (9%)
 Frame = +1

Query: 476 KYKHPAAVFGCDWSQNNKDMIATGCEDKNIRVFYVATSSNQPLKV--------FSGHTAR 527
           K  H   V    +   N  +IAT     ++ VF      ++P             GH   
Sbjct: 190 KINHEGEVNRARYMPQNPCIIATKTPSSDVLVFDYTKHPSKPDPSGECIPELRLKGHQKE 369

Query: 528 VFHVKWSPLREGILCSGSDDGSVRIWDYTQDACVSTL-------NGHTAPVRGLMWNTEI 580
            + + W+P   G L S SDD ++ +WD       S +        GHT+ V  + W+   
Sbjct: 370 GYGLSWNPNLNGHLLSASDDHTICLWDINSTQRESRVVDAHTIFTGHTSVVEDVAWHLLH 549

Query: 581 PYLLISGSWDYTIKVWDTRGGVCLD---TVYDHGADVYGLTCHPSRPFTMASCSRDSTVR 637
             L  S + D  + +WDTR          V  H A+V  L+ +P   F +A+ S D TV 
Sbjct: 550 ESLFGSVADDQKLMIWDTRSNTTSKPSHVVDAHTAEVNCLSFNPYSEFILATGSADKTVA 729

Query: 638 LWSL 641
           LW L
Sbjct: 730 LWDL 741

 Score = 60.8 bits (146), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 69/316 (21%), Positives = 123/316 (38%), Gaps = 41/316 (12%)
 Frame = +1

Query: 331 GGVGLYDMGAKKWDFLRELGHVETIFDCKFKPDDPNVLATASFDGTIKVWDINTLTAVYT 390
           G  G +   + K +   ++ H   +   ++ P +P ++AT +    + V+D    T   +
Sbjct: 139 GEFGGFGSVSGKIEIEIKINHEGEVNRARYMPQNPCIIATKTPSSDVLVFD---YTKHPS 309

Query: 391 SP-------------GNEGVIFALSWAPGDLNCIAGATSRNGAFIWDIQKGKIIQR---- 433
            P             G++   + LSW P     +  A+  +   +WDI   +   R    
Sbjct: 310 KPDPSGECIPELRLKGHQKEGYGLSWNPNLNGHLLSASDDHTICLWDINSTQRESRVVDA 489

Query: 434 ---FNEHGKNGIFYIAWSHKDSKRIATCSGDGFCIIRTVDGKLLHKYKH-----PAAVFG 485
              F  H  + +  +AW         + + D   +I         K  H      A V  
Sbjct: 490 HTIFTGH-TSVVEDVAWHLLHESLFGSVADDQKLMIWDTRSNTTSKPSHVVDAHTAEVNC 666

Query: 486 CDWSQNNKDMIATGCEDKNIRVFYVATSSNQPLKV--FSGHTARVFHVKWSPLREGILCS 543
             ++  ++ ++ATG  DK + ++ +    N  LK+  F  H   +F V+WSP  E IL S
Sbjct: 667 LSFNPYSEFILATGSADKTVALWDL---RNLKLKLHSFESHKDEIFQVQWSPHNETILAS 837

Query: 544 GSDDGSVRIWDYT--------QDA------CVSTLNGHTAPVRGLMWNTEIPYLLISGSW 589
              D  + +WD +        +DA       +    GHTA +    WN   P+++ S S 
Sbjct: 838 SGTDRRLHVWDLSKIGEEQLPEDAEDGPPELLFIHGGHTAKISDFSWNPNEPWIVCSVSE 1017

Query: 590 DYTIKVWDTRGGVCLD 605
           D  ++VW     +  D
Sbjct: 1018DNIMQVWQMAENIYSD 1065

 Score = 39.7 bits (91), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 19/49 (38%), Positives = 29/49 (59%)
 Frame = +1

Query: 43  DHRYNEFKLHAIMSEHKKTITAISWCPHNPDLFASSSTDNLVIIWNVAE 91
           D R  + KLH+  S HK  I  + W PHN  + ASS TD  + +W++++
Sbjct: 736 DLRNLKLKLHSFES-HKDEIFQVQWSPHNETILASSGTDRRLHVWDLSK 879

 Score = 32.0 bits (71), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 26/80 (32%), Positives = 40/80 (50%), Gaps = 4/80 (5%)
 Frame = +1

Query: 16  PWNKDVCAANG-DRFAYCATLA-IYIYQL--DHRYNEFKLHAIMSEHKKTITAISWCPHN 71
           P N+ + A++G DR  +   L+ I   QL  D      +L  I   H   I+  SW P+ 
Sbjct: 811 PHNETILASSGTDRRLHVWDLSKIGEEQLPEDAEDGPPELLFIHGGHTAKISDFSWNPNE 990

Query: 72  PDLFASSSTDNLVIIWNVAE 91
           P +  S S DN++ +W +AE
Sbjct: 991 PWIVCSVSEDNIMQVWQMAE 1050
>02960
          Length = 1577

 Score = 55.8 bits (133), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 35/103 (33%), Positives = 55/103 (53%), Gaps = 2/103 (1%)
 Frame = +2

Query: 495  MIATGCEDKNIRVFYVATSSNQPLK-VFSGHTARVFHVKWSPLREGILCSGSDDGSVRIW 553
            M+ TG  D+++R+     S  + +K  F+ HT  V  V WSP RE +  SGS D  +++W
Sbjct: 1121 MLITGSADRHVRLVDPRCSEGETVKCAFTSHTGWVTGVDWSPTREHLFLSGSYDNVLKLW 1300

Query: 554  D-YTQDACVSTLNGHTAPVRGLMWNTEIPYLLISGSWDYTIKV 595
            D  +  A +  +N H   +  + W+  IP LL+SG  D  + V
Sbjct: 1301 DTRSPKATLYDMNWHEDRILAVDWS--IPELLLSGGVDNKLHV 1423

 Score = 52.4 bits (124), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 65/277 (23%), Positives = 112/277 (40%), Gaps = 37/277 (13%)
 Frame = +2

Query: 370 TASFDGTIKVWDINTLTAVYTSPGNEGVIFALSWAPGD----LNCIAGATSRNGAFIWDI 425
           + S+D T+++W      A+ T PG+   +  ++W   D    ++     +    A +W  
Sbjct: 530 SGSYDNTVRLWSTKG-EAIMTIPGHTSPVKCVAWIKHDESSGVSTFVTGSHDQTALVWQW 706

Query: 426 QK--GKIIQRFNEHGKNGIFYIAWSHKDSKRIATCSGDGFCIIRT----VDGK------- 472
           Q+   ++  R +  G            DS+++ T S D    + +    VDG        
Sbjct: 707 QRETNEVDCRLSCRGHAASVDCVAVSPDSQQMCTGSWDKMLKLWSTDCNVDGDQSEDTER 886

Query: 473 -----------------LLHKYKHPAAVFGCDWSQNNKDMIATGCEDKNIRVFYVATSSN 515
                            +L    H  AV    W   ++  + T   D ++R++ + T+  
Sbjct: 887 PSKKKKSAKSTTQTRVPVLTLSGHAEAVSAVRWLDPHR--VVTSSWDHSLRLWDLHTA-- 1054

Query: 516 QPLKVFSGHTARVFHVKWSPLREGILCSGSDDGSVRIWD---YTQDACVSTLNGHTAPVR 572
           Q   +  G  A V  V +SPL   +L +GS D  VR+ D      +        HT  V 
Sbjct: 1055QQTSLIQGSKA-VLDVAYSPLSH-MLITGSADRHVRLVDPRCSEGETVKCAFTSHTGWVT 1228

Query: 573 GLMWNTEIPYLLISGSWDYTIKVWDTRGGVCLDTVYD 609
           G+ W+    +L +SGS+D  +K+WDTR      T+YD
Sbjct: 1229GVDWSPTREHLFLSGSYDNVLKLWDTRSPKA--TLYD 1333

 Score = 39.7 bits (91), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 34/110 (30%), Positives = 51/110 (46%), Gaps = 8/110 (7%)
 Frame = +2

Query: 539 GILCSGSDDGSVRIWDYTQDACVSTLNGHTAPVRGLMW----NTEIPYLLISGSWDYTIK 594
           G   SGS D +VR+W  T+   + T+ GHT+PV+ + W     +      ++GS D T  
Sbjct: 518 GXXLSGSYDNTVRLWS-TKGEAIMTIPGHTSPVKCVAWIKHDESSGVSTFVTGSHDQTAL 694

Query: 595 VW----DTRGGVCLDTVYDHGADVYGLTCHPSRPFTMASCSRDSTVRLWS 640
           VW    +T    C  +   H A V  +   P     M + S D  ++LWS
Sbjct: 695 VWQWQRETNEVDCRLSCRGHAASVDCVAVSPDSQ-QMCTGSWDKMLKLWS 841

 Score = 33.9 bits (76), Expect = 0.45,   Method: Compositional matrix adjust.
 Identities = 41/207 (19%), Positives = 82/207 (39%)
 Frame = +2

Query: 350  GHVETIFDCKFKPDDPNVLATASFDGTIKVWDINTLTAVYTSPGNEGVIFALSWAPGDLN 409
            GH E +   ++   DP+ + T+S+D ++++WD++T        G++ V+  ++++P    
Sbjct: 953  GHAEAVSAVRWL--DPHRVVTSSWDHSLRLWDLHTAQQTSLIQGSKAVL-DVAYSPLSHM 1123

Query: 410  CIAGATSRNGAFIWDIQKGKIIQRFNEHGKNGIFYIAWSHKDSKRIATCSGDGFCIIRTV 469
             I G+  R+            ++  +     G         ++ + A  S  G+      
Sbjct: 1124 LITGSADRH------------VRLVDPRCSEG---------ETVKCAFTSHTGW------ 1222

Query: 470  DGKLLHKYKHPAAVFGCDWSQNNKDMIATGCEDKNIRVFYVATSSNQPLKVFSGHTARVF 529
                         V G DWS   + +  +G  D N+   +   S    L   + H  R+ 
Sbjct: 1223 -------------VTGVDWSPTREHLFLSGSYD-NVLKLWDTRSPKATLYDMNWHEDRIL 1360

Query: 530  HVKWSPLREGILCSGSDDGSVRIWDYT 556
             V WS     +L SG  D  + ++ Y+
Sbjct: 1361 AVDWSIPE--LLLSGGVDNKLHVFSYS 1435

 Score = 30.0 bits (66), Expect = 5.8,   Method: Compositional matrix adjust.
 Identities = 15/57 (26%), Positives = 28/57 (49%), Gaps = 1/57 (1%)
 Frame = +2

Query: 38   YIYQLDHRYNEFK-LHAIMSEHKKTITAISWCPHNPDLFASSSTDNLVIIWNVAEQK 93
            ++  +D R +E + +    + H   +T + W P    LF S S DN++ +W+    K
Sbjct: 1148 HVRLVDPRCSEGETVKCAFTSHTGWVTGVDWSPTREHLFLSGSYDNVLKLWDTRSPK 1318
>13278
          Length = 870

 Score = 55.5 bits (132), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 31/120 (25%), Positives = 63/120 (52%), Gaps = 8/120 (6%)
 Frame = +1

Query: 355 IFDCKFKPDDPN--------VLATASFDGTIKVWDINTLTAVYTSPGNEGVIFALSWAPG 406
           I+  K+ P  P         +LA+ASFD T+++W++     ++T   ++  +++++++P 
Sbjct: 58  IYTIKWSPTGPGTSNPNTSLILASASFDSTVRLWEVERGLCLHTLTKHQEPVYSVAFSP- 234

Query: 407 DLNCIAGATSRNGAFIWDIQKGKIIQRFNEHGKNGIFYIAWSHKDSKRIATCSGDGFCII 466
           D   +A  +      IW++Q G ++  +   G  GIF + W+H+  K  A+ S DG   +
Sbjct: 235 DGKYLASGSFDKCVHIWNVQTGSLVHSYK--GTGGIFEVCWNHRGDKVGASAS-DGSVFV 405

 Score = 52.0 bits (123), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 39/148 (26%), Positives = 65/148 (43%), Gaps = 19/148 (12%)
 Frame = +1

Query: 525 TARVFHVKWSPLREG--------ILCSGSDDGSVRIWDYTQDACVSTLNGHTAPVRGLMW 576
           T  ++ +KWSP   G        IL S S D +VR+W+  +  C+ TL  H  PV  + +
Sbjct: 49  TKEIYTIKWSPTGPGTSNPNTSLILASASFDSTVRLWEVERGLCLHTLTKHQEPVYSVAF 228

Query: 577 NTEIPYLLISGSWDYTIKVWDTR-----------GGVCLDTVYDHGADVYGLTCHPSRPF 625
           + +  YL  SGS+D  + +W+ +           GG+  +  ++H  D  G +      F
Sbjct: 229 SPDGKYL-ASGSFDKCVHIWNVQTGSLVHSYKGTGGI-FEVCWNHRGDKVGASASDGSVF 402

Query: 626 TMASCSRDSTVRLWSLIPLITPLQINIL 653
            +     D     W ++ L+ PL    L
Sbjct: 403 VLDLRK*DKCSNSWHML-LLPPLSPKFL 483

 Score = 48.5 bits (114), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 28/98 (28%), Positives = 47/98 (47%), Gaps = 8/98 (8%)
 Frame = +1

Query: 552 IWDYTQDACVSTLNGHTAPVRGLMW--------NTEIPYLLISGSWDYTIKVWDTRGGVC 603
           IW   +D+C+  L   T  +  + W        N     +L S S+D T+++W+   G+C
Sbjct: 1   IWSMGKDSCIHDLQLTTKEIYTIKWSPTGPGTSNPNTSLILASASFDSTVRLWEVERGLC 180

Query: 604 LDTVYDHGADVYGLTCHPSRPFTMASCSRDSTVRLWSL 641
           L T+  H   VY +   P   + +AS S D  V +W++
Sbjct: 181 LHTLTKHQEPVYSVAFSPDGKY-LASGSFDKCVHIWNV 291
>01805
          Length = 2124

 Score = 54.3 bits (129), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 49/255 (19%), Positives = 95/255 (37%), Gaps = 21/255 (8%)
 Frame = -1

Query: 366 NVLATASFDGTIKVWDINTLTAV--------------------YTSPGNEGVIFALSWAP 405
           N +A  S +  I++WD++ + +V                     +  G+   +  LSW  
Sbjct: 723 NFVAIGSMEPVIEIWDLDIMESVGPTLTLGSKPKKTKKKMKQKESVTGHTQAVLDLSWNR 544

Query: 406 GDLNCIAGATSRNGAFIWDIQKGKIIQRFNEHGKNGIFYIAWSHKDSKRIATCSGDGFCI 465
              + +A A++     +WD+ +GK+   F                               
Sbjct: 543 NARHVLASASADTTVALWDLSEGKMAMNFT------------------------------ 454

Query: 466 IRTVDGKLLHKYKHPAAVFGCDWSQNNKDMIATGCEDKNIRVFYVATSSN-QPLKVFSGH 524
                       +H   V  C+W    +  + TG  D  ++V    ++          G 
Sbjct: 453 ------------QHSREVQCCNWHPQEEQTLLTGSFDNTVKVVDCRSAETCHKSWTVEGE 310

Query: 525 TARVFHVKWSPLREGILCSGSDDGSVRIWDYTQDACVSTLNGHTAPVRGLMWNTEIPYLL 584
             +      +PL+   L + +D G V  +D   +  V ++  H++ V G+  +++IP L+
Sbjct: 309 VEKAVWNHHNPLQ---LLACTDKGMVYCFDIRHEKPVFSVGAHSSCVTGVCLSSQIPGLM 139

Query: 585 ISGSWDYTIKVWDTR 599
           I+ S D T+KVWD +
Sbjct: 138 ITTSEDKTMKVWDIQ 94

 Score = 50.1 bits (118), Expect = 6e-06,   Method: Compositional matrix adjust.
 Identities = 28/115 (24%), Positives = 50/115 (43%)
 Frame = -1

Query: 522 SGHTARVFHVKWSPLREGILCSGSDDGSVRIWDYTQDACVSTLNGHTAPVRGLMWNTEIP 581
           +GHT  V  + W+     +L S S D +V +WD ++         H+  V+   W+ +  
Sbjct: 585 TGHTQAVLDLSWNRNARHVLASASADTTVALWDLSEGKMAMNFTQHSREVQCCNWHPQEE 406

Query: 582 YLLISGSWDYTIKVWDTRGGVCLDTVYDHGADVYGLTCHPSRPFTMASCSRDSTV 636
             L++GS+D T+KV D R        +    +V     +   P  + +C+    V
Sbjct: 405 QTLLTGSFDNTVKVVDCRSAETCHKSWTVEGEVEKAVWNHHNPLQLLACTDKGMV 241

 Score = 44.7 bits (104), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 24/76 (31%), Positives = 36/76 (47%)
 Frame = -1

Query: 563 TLNGHTAPVRGLMWNTEIPYLLISGSWDYTIKVWDTRGGVCLDTVYDHGADVYGLTCHPS 622
           ++ GHT  V  L WN    ++L S S D T+ +WD   G        H  +V     HP 
Sbjct: 591 SVTGHTQAVLDLSWNRNARHVLASASADTTVALWDLSEGKMAMNFTQHSREVQCCNWHPQ 412

Query: 623 RPFTMASCSRDSTVRL 638
              T+ + S D+TV++
Sbjct: 411 EEQTLLTGSFDNTVKV 364

 Score = 35.8 bits (81), Expect = 0.11,   Method: Compositional matrix adjust.
 Identities = 26/109 (23%), Positives = 43/109 (39%)
 Frame = -1

Query: 330 DGGVGLYDMGAKKWDFLRELGHVETIFDCKFKPDDPNVLATASFDGTIKVWDINTLTAVY 389
           D  V L+D+   K   +    H   +  C + P +   L T SFD T+KV D  +    +
Sbjct: 510 DTTVALWDLSEGKM-AMNFTQHSREVQCCNWHPQEEQTLLTGSFDNTVKVVDCRSAETCH 334

Query: 390 TSPGNEGVIFALSWAPGDLNCIAGATSRNGAFIWDIQKGKIIQRFNEHG 438
            S   EG +    W   +   +   T +   + +DI+  K +     H 
Sbjct: 333 KSWTVEGEVEKAVWNHHNPLQLLACTDKGMVYCFDIRHEKPVFSVGAHS 187

 Score = 30.4 bits (67), Expect = 4.5,   Method: Compositional matrix adjust.
 Identities = 13/53 (24%), Positives = 24/53 (45%)
 Frame = -1

Query: 58  HKKTITAISWCPHNPDLFASSSTDNLVIIWNVAEQKVIAKLDNIKETPACLGW 110
           H + +  +SW  +   + AS+S D  V +W+++E K+            C  W
Sbjct: 579 HTQAVLDLSWNRNARHVLASASADTTVALWDLSEGKMAMNFTQHSREVQCCNW 421
>19949
          Length = 903

 Score = 53.5 bits (127), Expect = 6e-07,   Method: Compositional matrix adjust.
 Identities = 35/100 (35%), Positives = 51/100 (51%)
 Frame = +2

Query: 542 CSGSDDGSVRIWDYTQDACVSTLNGHTAPVRGLMWNTEIPYLLISGSWDYTIKVWDTRGG 601
            SGS D +V++WD  +  C+ T  GHT  V  L ++ +  + + S S D  +K+WD   G
Sbjct: 41  ASGSMDCNVKLWDIRRKGCIYTYKGHTGCVCCLRFSPDGRW-IASASEDGLVKLWDLTAG 217

Query: 602 VCLDTVYDHGADVYGLTCHPSRPFTMASCSRDSTVRLWSL 641
             L  +  H   V  +  HP   F +AS S D TV+ W L
Sbjct: 218 KLLTDLKLHRDAVNTIEFHPHE-FLLASGSADRTVKFWDL 334

 Score = 48.5 bits (114), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 45/169 (26%), Positives = 79/169 (46%)
 Frame = +2

Query: 497 ATGCEDKNIRVFYVATSSNQPLKVFSGHTARVFHVKWSPLREGILCSGSDDGSVRIWDYT 556
           A+G  D N++++ +       +  + GHT  V  +++SP    I  S S+DG V++WD T
Sbjct: 41  ASGSMDCNVKLWDIRRKGC--IYTYKGHTGCVCCLRFSPDGRWI-ASASEDGLVKLWDLT 211

Query: 557 QDACVSTLNGHTAPVRGLMWNTEIPYLLISGSWDYTIKVWDTRGGVCLDTVYDHGADVYG 616
               ++ L  H   V  + ++    +LL SGS D T+K WD      + T       +  
Sbjct: 212 AGKLLTDLKLHRDAVNTIEFHPH-EFLLASGSADRTVKFWDLETFQLISTTEPEANSIRS 388

Query: 617 LTCHPSRPFTMASCSRDSTVRLWSLIPLITPLQINILADRSWDEVIGNT 665
           +  HP     + S S+D T++++   PL     +++   +  D  I NT
Sbjct: 389 ILFHPD-GVCLYSGSKD-TLKVYHWEPLELYDTVSVPWGQVCDMSISNT 529

 Score = 42.4 bits (98), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 22/69 (31%), Positives = 35/69 (50%)
 Frame = +2

Query: 369 ATASFDGTIKVWDINTLTAVYTSPGNEGVIFALSWAPGDLNCIAGATSRNGAFIWDIQKG 428
           A+ S D  +K+WDI     +YT  G+ G +  L ++P D   IA A+      +WD+  G
Sbjct: 41  ASGSMDCNVKLWDIRRKGCIYTYKGHTGCVCCLRFSP-DGRWIASASEDGLVKLWDLTAG 217

Query: 429 KIIQRFNEH 437
           K++     H
Sbjct: 218 KLLTDLKLH 244

 Score = 37.4 bits (85), Expect = 0.039,   Method: Compositional matrix adjust.
 Identities = 26/96 (27%), Positives = 47/96 (48%), Gaps = 1/96 (1%)
 Frame = +2

Query: 330 DGGVGLYDMGAKKWDFLRELG-HVETIFDCKFKPDDPNVLATASFDGTIKVWDINTLTAV 388
           DG V L+D+ A K   L +L  H + +   +F P +  +LA+ S D T+K WD+ T   +
Sbjct: 182 DGLVKLWDLTAGK--LLTDLKLHRDAVNTIEFHPHE-FLLASGSADRTVKFWDLETFQLI 352

Query: 389 YTSPGNEGVIFALSWAPGDLNCIAGATSRNGAFIWD 424
            T+      I ++ + P  +   +G+      + W+
Sbjct: 353 STTEPEANSIRSILFHPDGVCLYSGSKDTLKVYHWE 460
>19140
          Length = 573

 Score = 50.8 bits (120), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 38/145 (26%), Positives = 63/145 (43%), Gaps = 1/145 (0%)
 Frame = -3

Query: 498 TGCEDKNIRVFYVATSSNQPLKVFSGHTARVFHVKWSPLREGILC-SGSDDGSVRIWDYT 556
           + C+D+      +   +   L    GHT  V  +  +  R+G  C SGS DG++R+W   
Sbjct: 568 SSCQDQRKSSACLGPRTCHKLMKLKGHTDNVKALVLN--RDGTQCLSGSSDGTIRLWSLG 395

Query: 557 QDACVSTLNGHTAPVRGLMWNTEIPYLLISGSWDYTIKVWDTRGGVCLDTVYDHGADVYG 616
           Q  CV+T   H   V  L  N      L SG  D+ +   D +     + + +  A V  
Sbjct: 394 QQRCVATFRVHDEGVWALQANESF-TTLYSGGRDHQVWATDIKNPDNRELICEEKAPVLK 218

Query: 617 LTCHPSRPFTMASCSRDSTVRLWSL 641
           L   P+ P ++   + DS ++ W +
Sbjct: 217 LELTPTDPPSLWVATTDSCIKNWPV 143
>12841
          Length = 1364

 Score = 50.8 bits (120), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 23/64 (35%), Positives = 36/64 (56%)
 Frame = +1

Query: 514  SNQPLKVFSGHTARVFHVKWSPLREGILCSGSDDGSVRIWDYTQDACVSTLNGHTAPVRG 573
            + Q L+ +SGHTA V+H++WSP    I  S S D S+R+W   +   + T +  T  V  
Sbjct: 1015 NEQYLETYSGHTAPVYHIRWSPFVSDIFLSCSADWSIRLWHQDRTTPILTFHSSTKTVHD 1194

Query: 574  LMWN 577
            + W+
Sbjct: 1195 VCWS 1206

 Score = 37.4 bits (85), Expect = 0.035,   Method: Compositional matrix adjust.
 Identities = 61/295 (20%), Positives = 109/295 (36%), Gaps = 46/295 (15%)
 Frame = +1

Query: 14  CQPWNK---DVCAANGDRFAYCATLAIYIYQLDHRYNEFKLHAIMSEHKKTITAISWCPH 70
           C  WNK   D+ A    +F +    +  I     +  E+      S H   +T++ +   
Sbjct: 415 CLAWNKSNPDLVAVGYGQFDFTNQKSGLICCWSLKNPEYPERVYTSTHG--VTSLDFSVA 588

Query: 71  NPDLFASSSTDNLVIIWNVAEQKVIAKLDNIKETPACLGWCWNTH-------------DA 117
           N ++ A+   D  V I+NV        LDN +     LG  W                + 
Sbjct: 589 NANILAAGYYDGGVAIYNVRSTSDEPILDNQETHGKHLGPVWQIQWIEKERGSGEERAEV 768

Query: 118 VAFVSQKGPLLIWTI-SGPDS--------------GVSVHKEAHSF----ASDICIFRWH 158
           +  +S  G +  W+I  G +S              G +  K+  +F    A  +C F +H
Sbjct: 769 LISISTDGRVTQWSIRKGFESNNIMRLKKLPTRMAGKAREKKGEAFISRHAGGLC-FDFH 945

Query: 159 TQKKGKVAFGHIDGSISIFQPDEED-----------PVTALEWDPLSTDYLLVANLHFGI 207
           ++       G  +G I        +           PV  + W P  +D  L  +  + I
Sbjct: 946 SRDLNVYLAGTEEGYIHKCSCSYNEQYLETYSGHTAPVYHIRWSPFVSDIFLSCSADWSI 1125

Query: 208 RLLDSESLYCITTFNLPSAAVSVQCLAWVPSAPGMFITGDSQVGVLRIWNVSRTT 262
           RL   +    I TF+  S+  +V  + W P +  +F       G + +W+++++T
Sbjct: 1126RLWHQDRTTPILTFH--SSTKTVHDVCWSPRSSTVFAC--VHEGAVEVWDLAQST 1278

 Score = 30.4 bits (67), Expect = 5.0,   Method: Compositional matrix adjust.
 Identities = 14/81 (17%), Positives = 34/81 (41%)
 Frame = +1

Query: 350  GHVETIFDCKFKPDDPNVLATASFDGTIKVWDINTLTAVYTSPGNEGVIFALSWAPGDLN 409
            GH   ++  ++ P   ++  + S D +I++W  +  T + T   +   +  + W+P    
Sbjct: 1042 GHTAPVYHIRWSPFVSDIFLSCSADWSIRLWHQDRTTPILTFHSSTKTVHDVCWSPRSST 1221

Query: 410  CIAGATSRNGAFIWDIQKGKI 430
              A         +WD+ +  +
Sbjct: 1222 VFA-CVHEGAVEVWDLAQSTL 1281
>17602
          Length = 481

 Score = 50.4 bits (119), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 30/90 (33%), Positives = 50/90 (55%), Gaps = 1/90 (1%)
 Frame = +3

Query: 551 RIWDYTQDACVSTLNGHTAPVRGLMWNTEIPYLLISGSWDYTIKVWDTRGGVCLDT-VYD 609
           RIWD     C+ TL  H+ PV  + +N +   L++S S+D   ++WDT  G CL T + D
Sbjct: 3   RIWDVKTGKCLKTLPAHSDPVTAVHFNRD-GSLIVSSSYDGLCRIWDTASGQCLXTLIDD 179

Query: 610 HGADVYGLTCHPSRPFTMASCSRDSTVRLW 639
               V  +   P+  + +A+ + D+T++LW
Sbjct: 180 DNPPVSFVKFSPNGKYILAA-TLDNTLKLW 266

 Score = 47.8 bits (112), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 43/141 (30%), Positives = 70/141 (49%), Gaps = 4/141 (2%)
 Frame = +3

Query: 506 RVFYVATSSNQPLKVFSGHTARVFHVKWSPLREG-ILCSGSDDGSVRIWDYTQDACVSTL 564
           R++ V T   + LK    H+  V  V ++  R+G ++ S S DG  RIWD     C+ TL
Sbjct: 3   RIWDVKTG--KCLKTLPAHSDPVTAVHFN--RDGSLIVSSSYDGLCRIWDTASGQCLXTL 170

Query: 565 -NGHTAPVRGLMWNTEIPYLLISGSWDYTIKVWDTRGGVCLDTVYDHGADVYGLTCHPSR 623
            +    PV  + ++    Y+L + + D T+K+WD   G CL T   H  + Y +  + S 
Sbjct: 171 IDDDNPPVSFVKFSPNGKYIL-AATLDNTLKLWDYSKGKCLKTYVGHRNEKYCIFANFSV 347

Query: 624 PFT--MASCSRDSTVRLWSLI 642
                + S S D+ V +W+L+
Sbjct: 348 TGGKWIVSGSEDNMVYIWNLL 410

 Score = 30.4 bits (67), Expect = 4.7,   Method: Compositional matrix adjust.
 Identities = 17/74 (22%), Positives = 35/74 (47%)
 Frame = +3

Query: 364 DPNVLATASFDGTIKVWDINTLTAVYTSPGNEGVIFALSWAPGDLNCIAGATSRNGAFIW 423
           D +++ ++S+DG  ++WD  +   + T   ++    +      +   I  AT  N   +W
Sbjct: 87  DGSLIVSSSYDGLCRIWDTASGQCLXTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLW 266

Query: 424 DIQKGKIIQRFNEH 437
           D  KGK ++ +  H
Sbjct: 267 DYSKGKCLKTYVGH 308
>26939
          Length = 388

 Score = 50.4 bits (119), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 30/85 (35%), Positives = 43/85 (50%), Gaps = 7/85 (8%)
 Frame = +2

Query: 541 LCSGSDDGSVRIWDYTQDACVSTLNGHTAPVRGLMWNTEIPYLLISGSWDYTIKVWDTR- 599
           L S SDD ++R+WD     C+ TL  H      + ++   PY +ISGS D T+KVW+ R 
Sbjct: 11  LVSASDDKTIRVWDLRNKRCMKTLYAHQHFCTSIDFHKAHPY-VISGSVDQTVKVWECR* 187

Query: 600 ----GGVCLDTVYD--HGADVYGLT 618
                 +CL    +  H  + Y LT
Sbjct: 188 EHSANNICLFLNLNIIHKNNTYNLT 262

 Score = 42.7 bits (99), Expect = 8e-04,   Method: Compositional matrix adjust.
 Identities = 22/56 (39%), Positives = 32/56 (57%)
 Frame = +2

Query: 584 LISGSWDYTIKVWDTRGGVCLDTVYDHGADVYGLTCHPSRPFTMASCSRDSTVRLW 639
           L+S S D TI+VWD R   C+ T+Y H      +  H + P+ + S S D TV++W
Sbjct: 11  LVSASDDKTIRVWDLRNKRCMKTLYAHQHFCTSIDFHKAHPYVI-SGSVDQTVKVW 175
>12574
          Length = 521

 Score = 50.1 bits (118), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 31/97 (31%), Positives = 53/97 (54%)
 Frame = +3

Query: 492 NKDMIATGCEDKNIRVFYVATSSNQPLKVFSGHTARVFHVKWSPLREGILCSGSDDGSVR 551
           N D +A+   DK I+++       +  K  +GH   +  V WS   + +LCS SDD +++
Sbjct: 219 NGDWLASSSADKLIKIW--GAYDGKFEKTIAGHKLGLSDVAWSSDSK-LLCSASDDKTLK 389

Query: 552 IWDYTQDACVSTLNGHTAPVRGLMWNTEIPYLLISGS 588
           IW+++   C+ TL GH+  V    +N +   L++SGS
Sbjct: 390 IWEFSTGKCMKTLKGHSNYVFCCNFNPQ-SNLIVSGS 497

 Score = 47.8 bits (112), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 31/102 (30%), Positives = 50/102 (49%)
 Frame = +3

Query: 520 VFSGHTARVFHVKWSPLREGILCSGSDDGSVRIWDYTQDACVSTLNGHTAPVRGLMWNTE 579
             +GHT  +  VK+SP  +  L S S D  ++IW         T+ GH   +  + W+++
Sbjct: 171 TLAGHTKALSAVKFSPNGD-WLASSSADKLIKIWGAYDGKFEKTIAGHKLGLSDVAWSSD 347

Query: 580 IPYLLISGSWDYTIKVWDTRGGVCLDTVYDHGADVYGLTCHP 621
              LL S S D T+K+W+   G C+ T+  H   V+    +P
Sbjct: 348 -SKLLCSASDDKTLKIWEFSTGKCMKTLKGHSNYVFCCNFNP 470

 Score = 32.3 bits (72), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 16/45 (35%), Positives = 25/45 (55%)
 Frame = +3

Query: 49  FKLHAIMSEHKKTITAISWCPHNPDLFASSSTDNLVIIWNVAEQK 93
           + L   ++ H K ++A+ + P N D  ASSS D L+ IW   + K
Sbjct: 156 YTLKFTLAGHTKALSAVKFSP-NGDWLASSSADKLIKIWGAYDGK 287
>16105
          Length = 960

 Score = 50.1 bits (118), Expect = 6e-06,   Method: Compositional matrix adjust.
 Identities = 35/136 (25%), Positives = 64/136 (47%), Gaps = 7/136 (5%)
 Frame = -2

Query: 350 GHVETIFDCKFKPDDPNVLATASFDGTIKVWDI--NTLTAVYTSP-----GNEGVIFALS 402
           GH   + D ++ P + NV+A+AS D T+KVW I  + L    T P     G++     + 
Sbjct: 581 GHKGAVLDIQWCPHNDNVIASASDDCTVKVWQIPDSGLVTNLTDPVVDLVGHQKRCCLIV 402

Query: 403 WAPGDLNCIAGATSRNGAFIWDIQKGKIIQRFNEHGKNGIFYIAWSHKDSKRIATCSGDG 462
           W P   N +  A + N    W++  G+ +   +    + I+ ++++   S+ + TC    
Sbjct: 401 WHPSAQNVLVSAGADNKILFWNVGTGEPMLEVDV--PDMIYCMSFNFNGSRLVCTCKDKK 228

Query: 463 FCIIRTVDGKLLHKYK 478
             II +  G +L + K
Sbjct: 227 LRIIDSHSGAVLKEGK 180

 Score = 43.1 bits (100), Expect = 6e-04,   Method: Compositional matrix adjust.
 Identities = 22/89 (24%), Positives = 39/89 (43%), Gaps = 7/89 (7%)
 Frame = -2

Query: 520 VFSGHTARVFHVKWSPLREGILCSGSDDGSVRIWDYTQDACVSTLN-------GHTAPVR 572
           + +GH   V  ++W P  + ++ S SDD +V++W       V+ L        GH     
Sbjct: 590 LVAGHKGAVLDIQWCPHNDNVIASASDDCTVKVWQIPDSGLVTNLTDPVVDLVGHQKRCC 411

Query: 573 GLMWNTEIPYLLISGSWDYTIKVWDTRGG 601
            ++W+     +L+S   D  I  W+   G
Sbjct: 410 LIVWHPSAQNVLVSAGADNKILFWNVGTG 324

 Score = 41.2 bits (95), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 15/45 (33%), Positives = 27/45 (60%)
 Frame = -2

Query: 54  IMSEHKKTITAISWCPHNPDLFASSSTDNLVIIWNVAEQKVIAKL 98
           +++ HK  +  I WCPHN ++ AS+S D  V +W + +  ++  L
Sbjct: 590 LVAGHKGAVLDIQWCPHNDNVIASASDDCTVKVWQIPDSGLVTNL 456

 Score = 40.0 bits (92), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 20/81 (24%), Positives = 36/81 (44%), Gaps = 5/81 (6%)
 Frame = -2

Query: 479 HPAAVFGCDWSQNNKDMIATGCEDKNIRVFYV-----ATSSNQPLKVFSGHTARVFHVKW 533
           H  AV    W  +N ++IA+  +D  ++V+ +      T+   P+    GH  R   + W
Sbjct: 578 HKGAVLDIQWCPHNDNVIASASDDCTVKVWQIPDSGLVTNLTDPVVDLVGHQKRCCLIVW 399

Query: 534 SPLREGILCSGSDDGSVRIWD 554
            P  + +L S   D  +  W+
Sbjct: 398 HPSAQNVLVSAGADNKILFWN 336

 Score = 32.3 bits (72), Expect = 1.4,   Method: Compositional matrix adjust.
 Identities = 19/77 (24%), Positives = 36/77 (46%)
 Frame = -2

Query: 58  HKKTITAISWCPHNPDLFASSSTDNLVIIWNVAEQKVIAKLDNIKETPACLGWCWNTHDA 117
           H+K    I W P   ++  S+  DN ++ WNV   + + ++D + +   C+ + +N    
Sbjct: 428 HQKRCCLIVWHPSAQNVLVSAGADNKILFWNVGTGEPMLEVD-VPDMIYCMSFNFNGSRL 252

Query: 118 VAFVSQKGPLLIWTISG 134
           V     K   +I + SG
Sbjct: 251 VCTCKDKKLRIIDSHSG 201

 Score = 30.4 bits (67), Expect = 5.1,   Method: Compositional matrix adjust.
 Identities = 20/83 (24%), Positives = 33/83 (39%), Gaps = 7/83 (8%)
 Frame = -2

Query: 566 GHTAPVRGLMWNTEIPYLLISGSWDYTIKVWDTRGGVCLDTVYDHGADVYG-------LT 618
           GH   V  + W      ++ S S D T+KVW       +  + D   D+ G       + 
Sbjct: 581 GHKGAVLDIQWCPHNDNVIASASDDCTVKVWQIPDSGLVTNLTDPVVDLVGHQKRCCLIV 402

Query: 619 CHPSRPFTMASCSRDSTVRLWSL 641
            HPS    + S   D+ +  W++
Sbjct: 401 WHPSAQNVLVSAGADNKILFWNV 333
>13335
          Length = 863

 Score = 49.3 bits (116), Expect = 9e-06,   Method: Compositional matrix adjust.
 Identities = 50/242 (20%), Positives = 98/242 (40%), Gaps = 21/242 (8%)
 Frame = +1

Query: 421 FIWDIQKGKIIQRFNEHGKNGIFYIAWSHKDSKRIATCSGDGFCIIRTVDGKLLHKY-KH 479
            +WD++ G I   +    K+ I    +S   S  ++    D  C+      KL+  Y  H
Sbjct: 7   IVWDVKTGSIKGEYQHASKSSIRVCKFSPSSSHLVSGSDDDTICMWEVATQKLVRSYVGH 186

Query: 480 PAAVFGCDWSQNNKDMIATGCEDKNIRVFYVATSSNQPLKV-FSGHTARVFHVKWSPLRE 538
             +V    +S N   ++ +G  + ++ V+  +    + L +    H   V   ++SP   
Sbjct: 187 EDSVMALAYSPNGHYLV-SGSPNGDLYVWDASFGHCRHLTLRVDAHDLGVTCCEFSPTFG 363

Query: 539 G-----------ILCSGSDDGSVRIWDYTQDA--------CVSTLNGHTAPVRGLMWNTE 579
                       +L +G  D  +++W ++           C   L+GH+  V    ++  
Sbjct: 364 TACAENSSTCNLLLATGGKDNLIKLWTFSAQVGSPEVTLQCRDILSGHSDLVMACAFSPS 543

Query: 580 IPYLLISGSWDYTIKVWDTRGGVCLDTVYDHGADVYGLTCHPSRPFTMASCSRDSTVRLW 639
              LL SGS+D ++++WD+  GV L ++    +              +AS S D  +++W
Sbjct: 544 -SALLASGSFDKSVRLWDSVKGVALFSIEACHSRFVTCCAFSIDGTLLASGSMDRIIKIW 720

Query: 640 SL 641
            L
Sbjct: 721 KL 726

 Score = 32.7 bits (73), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 13/41 (31%), Positives = 24/41 (58%)
 Frame = +1

Query: 350 GHVETIFDCKFKPDDPNVLATASFDGTIKVWDINTLTAVYT 390
           GH + +  C F P    +LA+ SFD ++++WD     A+++
Sbjct: 502 GHSDLVMACAFSPSSA-LLASGSFDKSVRLWDSVKGVALFS 621
>01598
          Length = 1545

 Score = 48.9 bits (115), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 52/213 (24%), Positives = 92/213 (43%), Gaps = 25/213 (11%)
 Frame = +1

Query: 367 VLATASFDGTIKVWDINTLTAVYT--------SPGNEGVIF----ALSWAPGDLNCIAGA 414
           ++AT S D TI+VW ++    ++           G+ G  F    A+ W   +   +  +
Sbjct: 106 LIATGSKDRTIRVWTLSQGKQIFMKKLPNQRREAGDTGSRFKVWLAIHWLKSNPEQLVSS 285

Query: 415 TSRNGAFIWDIQ--KGKIIQRFNEHG----KNGIFYIAWSHKDSKRIATCSGDGFCIIRT 468
           +S     +W ++  KG+  Q F           +F I  S  DSK + T + D   ++  
Sbjct: 286 SSGGDLLLWSLRYTKGQAYQTFQTSDYRPHMRPVFNICASGPDSKTLCTFAQDRQVVLW- 462

Query: 469 VDGKLLHKYKHPAAVFGCDW----SQNNKDMIATGCEDKNIRVFYVATSSNQPLKV---F 521
            D + +      A + G  +    S  +   +A G  D  IR + ++  +N P  V   +
Sbjct: 463 -DLETMEAVASMATLGGHVYCVRTSPIDPGRVAVGVGDSMIRTWNMSNKTN-PYDVTTLW 636

Query: 522 SGHTARVFHVKWSPLREGILCSGSDDGSVRIWD 554
            G  ++V  V W P +EG L  G+DDG + ++D
Sbjct: 637 QGIKSKVTAVAWHPTKEGWLGFGTDDGRIGVFD 735

 Score = 45.4 bits (106), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 84/392 (21%), Positives = 144/392 (36%), Gaps = 2/392 (0%)
 Frame = +1

Query: 207 IRLLDSESLYCITTFNLPSAAVSVQCLAWVPSAPGMFITGDSQVGVLRIWNVS-RTTPID 265
           + L D E++  + +  + +    V C+   P  PG    G     ++R WN+S +T P D
Sbjct: 451 VVLWDLETMEAVAS--MATLGGHVYCVRTSPIDPGRVAVGVGD-SMIRTWNMSNKTNPYD 621

Query: 266 NFKLKKTGFHCFHVVNSPPKKKFSVQSPNKNHYISSTSEAVPPPNLTQNQAFSLPPGHVV 325
              L +        V   P K+  +     +  I    + +     T +  F     +VV
Sbjct: 622 VTTLWQGIKSKVTAVAWHPTKEGWLGFGTDDGRIG-VFDVLSHKMPTLSNTFHHRTAYVV 798

Query: 326 CCFLDGGVGLYDMGAKKWDFLRELGHVETIFDCKFKPDDPNVLATASFDGTIKVWDINTL 385
           C    G   L     K +          ++ DCK       VL+    +      DI   
Sbjct: 799 CW---GPASLSPTDGKSFSLY-------SVGDCKILEHSSAVLSRG--EKKANAIDITQK 942

Query: 386 TAVYTSPGNEGV-IFALSWAPGDLNCIAGATSRNGAFIWDIQKGKIIQRFNEHGKNGIFY 444
                S   +G+    LSW+P D N  A  T     ++  IQ  KI+       K  I  
Sbjct: 943 IGAVNSDQVKGLKATELSWSP-DQNAAAVGTDEGSVYVVTIQDLKIVAAIRTQQKL-INC 1116

Query: 445 IAWSHKDSKRIATCSGDGFCIIRTVDGKLLHKYKHPAAVFGCDWSQNNKDMIATGCEDKN 504
           + W  + + +  + +G   C              H  A  G D   +  D+ +   E + 
Sbjct: 1117VRWHPRLTDQ--SPAGSPCC--------------HWLAAAGNDQVIHVVDLASVFAEREG 1248

Query: 505 IRVFYVATSSNQPLKVFSGHTARVFHVKWSPLREGILCSGSDDGSVRIWDYTQDACVSTL 564
            +   +  +S   L+  SGH+ RV  + WSP  +  L S   D    +WD  +   ++  
Sbjct: 1249DKETSLILTS---LRELSGHSQRVTDMSWSPHHDARLVSVGYDAEAFVWDVQKGTALAQF 1419

Query: 565 NGHTAPVRGLMWNTEIPYLLISGSWDYTIKVW 596
            GH   +    ++   P L+++G  D ++ VW
Sbjct: 1420KGHMGRLLTCQFSGLDPDLVMTGGSDASVHVW 1515

 Score = 37.0 bits (84), Expect = 0.047,   Method: Compositional matrix adjust.
 Identities = 105/509 (20%), Positives = 177/509 (34%), Gaps = 8/509 (1%)
 Frame = +1

Query: 60  KTITAISWCPHNPDLFASSSTDNLVIIWNVAEQKVIAKLDNIKETPACLGWCWNTHDAVA 119
           K   AI W   NP+   SSS+   +++W++   K               G  + T     
Sbjct: 229 KVWLAIHWLKSNPEQLVSSSSGGDLLLWSLRYTK---------------GQAYQTFQTSD 363

Query: 120 FVSQKGPLLIWTISGPDSGVSVHKEAHSFASDICIFRWHTQKKGKVA-FGHIDGSISIFQ 178
           +     P+     SGPDS     K   +FA D  +  W  +    VA    + G +   +
Sbjct: 364 YRPHMRPVFNICASGPDS-----KTLCTFAQDRQVVLWDLETMEAVASMATLGGHVYCVR 528

Query: 179 PDEEDPVTALEWDPLSTDYLLVANLHFGIR---LLDSESLYCITTFNLPSAAVSVQCLAW 235
               DP             + V      IR   + +  + Y +TT         V  +AW
Sbjct: 529 TSPIDP-----------GRVAVGVGDSMIRTWNMSNKTNPYDVTTL-WQGIKSKVTAVAW 672

Query: 236 VPSAPGM--FITGDSQVGVLRIWNVSRTTPIDNFKLKKTGFHCFHVVNSPPK--KKFSVQ 291
            P+  G   F T D ++GV  + +    T  + F  +     C+   +  P   K FS+ 
Sbjct: 673 HPTKEGWLGFGTDDGRIGVFDVLSHKMPTLSNTFHHRTAYVVCWGPASLSPTDGKSFSLY 852

Query: 292 SPNKNHYISSTSEAVPPPNLTQNQAFSLPPGHVVCCFLDGGVGLYDMGAKKWDFLRELGH 351
           S      +  +S AV      +  A  +                  +GA   D ++ L  
Sbjct: 853 SVGDCKILEHSS-AVLSRGEKKANAIDI---------------TQKIGAVNSDQVKGLKA 984

Query: 352 VETIFDCKFKPDDPNVLATASFDGTIKVWDINTLTAVYTSPGNEGVIFALSWAPGDLNCI 411
            E      + PD  N  A  + +G++ V  I  L  V      + +I  + W P  L   
Sbjct: 985 TE----LSWSPDQ-NAAAVGTDEGSVYVVTIQDLKIVAAIRTQQKLINCVRWHP-RLTDQ 1146

Query: 412 AGATSRNGAFIWDIQKGKIIQRFNEHGKNGIFYIAWSHKDSKRIATCSGDGFCIIRTVDG 471
           + A S    ++      ++I   +      +F      K++  I T        +R + G
Sbjct: 1147SPAGSPCCHWLAAAGNDQVIHVVD---LASVFAEREGDKETSLILTS-------LRELSG 1296

Query: 472 KLLHKYKHPAAVFGCDWSQNNKDMIATGCEDKNIRVFYVATSSNQPLKVFSGHTARVFHV 531
                  H   V    WS ++   + +   D    V+ V   +   L  F GH  R+   
Sbjct: 1297-------HSQRVTDMSWSPHHDARLVSVGYDAEAFVWDVQKGT--ALAQFKGHMGRLLTC 1449

Query: 532 KWSPLREGILCSGSDDGSVRIWDYTQDAC 560
           ++S L   ++ +G  D SV +W  +Q A 
Sbjct: 1450QFSGLDPDLVMTGGSDASVHVWRVSQQAA 1536

 Score = 32.7 bits (73), Expect = 0.95,   Method: Compositional matrix adjust.
 Identities = 69/345 (20%), Positives = 125/345 (36%), Gaps = 33/345 (9%)
 Frame = +1

Query: 241 GMFITGDSQVGVLRIWNVSRTTPIDNFKL----KKTG--------FHCFHVVNSPPKKKF 288
           G  I   S+   +R+W +S+   I   KL    ++ G        +   H + S P++  
Sbjct: 100 GCLIATGSKDRTIRVWTLSQGKQIFMKKLPNQRREAGDTGSRFKVWLAIHWLKSNPEQLV 279

Query: 289 SVQS------------PNKNHYISSTSEAVPPPNLTQNQAFSLPPGHVVCCFL-DGGVGL 335
           S  S              + +    TS+  P      N   S P    +C F  D  V L
Sbjct: 280 SSSSGGDLLLWSLRYTKGQAYQTFQTSDYRPHMRPVFNICASGPDSKTLCTFAQDRQVVL 459

Query: 336 YDMGAKKWDFLRELGHVET----IFDCKFKPDDPNVLATASFDGTIKVWDINTLTAVYTS 391
           +D+     + +  +  + T    ++  +  P DP  +A    D  I+ W+++  T  Y  
Sbjct: 460 WDL-----ETMEAVASMATLGGHVYCVRTSPIDPGRVAVGVGDSMIRTWNMSNKTNPYDV 624

Query: 392 P----GNEGVIFALSWAPGDLNCIAGATSRNGAFIWDIQKGKIIQRFNEHGKNGIFYIAW 447
                G +  + A++W P     +   T      ++D+   K+    N       + + W
Sbjct: 625 TTLWQGIKSKVTAVAWHPTKEGWLGFGTDDGRIGVFDVLSHKMPTLSNTFHHRTAYVVCW 804

Query: 448 SHKDSKRIATCSGDGFCIIRTVDGKLLHKYKHPAAVFGCDWSQNNKDMIATGCEDKNIRV 507
                  ++   G  F +    D K+L   +H +AV     S+  K   A    D   ++
Sbjct: 805 G---PASLSPTDGKSFSLYSVGDCKIL---EHSSAVL----SRGEKKANAI---DITQKI 945

Query: 508 FYVATSSNQPLKVFSGHTARVFHVKWSPLREGILCSGSDDGSVRI 552
             V +   + LK           + WSP  +     G+D+GSV +
Sbjct: 946 GAVNSDQVKGLK--------ATELSWSP-DQNAAAVGTDEGSVYV 1053

 Score = 32.3 bits (72), Expect = 1.4,   Method: Compositional matrix adjust.
 Identities = 18/81 (22%), Positives = 37/81 (45%), Gaps = 3/81 (3%)
 Frame = +1

Query: 21   VCAANGDRFAYCATLA-IYIYQLDHRYNEFKLHAI--MSEHKKTITAISWCPHNPDLFAS 77
            + AA  D+  +   LA ++  +   +     L ++  +S H + +T +SW PH+     S
Sbjct: 1177 LAAAGNDQVIHVVDLASVFAEREGDKETSLILTSLRELSGHSQRVTDMSWSPHHDARLVS 1356

Query: 78   SSTDNLVIIWNVAEQKVIAKL 98
               D    +W+V +   +A+ 
Sbjct: 1357 VGYDAEAFVWDVQKGTALAQF 1419

 Score = 32.0 bits (71), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 23/86 (26%), Positives = 37/86 (43%), Gaps = 2/86 (2%)
 Frame = +1

Query: 564  LNGHTAPVRGLMWNTEIPYLLISGSWDYTIKVWDTRGGVCLDTVYDHGADVYGLTCHPS- 622
            L+GH+  V  + W+      L+S  +D    VWD + G  L     H   +  LTC  S 
Sbjct: 1288 LSGHSQRVTDMSWSPHHDARLVSVGYDAEAFVWDVQKGTALAQFKGHMGRL--LTCQFSG 1461

Query: 623  -RPFTMASCSRDSTVRLWSLIPLITP 647
              P  + +   D++V +W +     P
Sbjct: 1462 LDPDLVMTGGSDASVHVWRVSQQAAP 1539
>12806
          Length = 961

 Score = 47.0 bits (110), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 30/113 (26%), Positives = 51/113 (45%), Gaps = 10/113 (8%)
 Frame = +3

Query: 540 ILCSGSDDGSVRIWDY----------TQDACVSTLNGHTAPVRGLMWNTEIPYLLISGSW 589
            L SG  D ++ +WD           T      TL GH+  +  L  + +  + L S SW
Sbjct: 51  FLISGGRDNNIIVWDL*PKKDGDEDQTWGVPRKTLTGHSHFISDLALSADSRFAL-SSSW 227

Query: 590 DYTIKVWDTRGGVCLDTVYDHGADVYGLTCHPSRPFTMASCSRDSTVRLWSLI 642
           D T+++WD + G       +H  DV  +   P     +AS  RD  +++W+++
Sbjct: 228 DATLRLWDIKKGSTTSRFINHTRDVLTVAFSPDNR-QIASGGRDKNLKIWNIM 383

 Score = 43.5 bits (101), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 38/128 (29%), Positives = 57/128 (44%), Gaps = 7/128 (5%)
 Frame = +3

Query: 521 FSGHTARVFHVKWSPLREGILCSGSDDGSVRIWD------YTQDACVSTLNGHTAPVRGL 574
           F  HT  V  V +SP    I  SG  D +++IW+      YT DA     N HT  V  +
Sbjct: 279 FINHTRDVLTVAFSPDNRQI-ASGGRDKNLKIWNIMGECKYTVDA-----NAHTDWVTCV 440

Query: 575 MWNTEIPY-LLISGSWDYTIKVWDTRGGVCLDTVYDHGADVYGLTCHPSRPFTMASCSRD 633
            ++ +    +++S S D TIKVWD       +T   H A +  L    +    + S S+D
Sbjct: 441 RFHQDTKNPIVVSASNDKTIKVWDNHTMTLKNTFVGHKAQITALDMSTNY---LVSGSKD 611

Query: 634 STVRLWSL 641
                W++
Sbjct: 612 GIAMTWNV 635

 Score = 41.2 bits (95), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 33/124 (26%), Positives = 58/124 (46%), Gaps = 1/124 (0%)
 Frame = +3

Query: 479 HPAAVFGCDWSQNNKDMIATGCEDKNIRVFYVATSSNQPLKVFSGHTARVFHVKW-SPLR 537
           H   V    +S +N+  IA+G  DKN++++ +       +   + HT  V  V++    +
Sbjct: 288 HTRDVLTVAFSPDNR-QIASGGRDKNLKIWNIMGECKYTVDA-NAHTDWVTCVRFHQDTK 461

Query: 538 EGILCSGSDDGSVRIWDYTQDACVSTLNGHTAPVRGLMWNTEIPYLLISGSWDYTIKVWD 597
             I+ S S+D ++++WD       +T  GH A +  L  +T     L+SGS D     W+
Sbjct: 462 NPIVVSASNDKTIKVWDNHTMTLKNTFVGHKAQITALDMSTN---YLVSGSKDGIAMTWN 632

Query: 598 TRGG 601
              G
Sbjct: 633 VAEG 644

 Score = 40.0 bits (92), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 32/111 (28%), Positives = 55/111 (49%), Gaps = 9/111 (8%)
 Frame = +3

Query: 334 GLYDMGAKKWDFLREL-------GHVETIFDCKFKPDDPN-VLATASFDGTIKVWDINTL 385
           G  D   K W+ + E         H + +   +F  D  N ++ +AS D TIKVWD +T+
Sbjct: 345 GGRDKNLKIWNIMGECKYTVDANAHTDWVTCVRFHQDTKNPIVVSASNDKTIKVWDNHTM 524

Query: 386 TAVYTSPGNEGVIFALSWAPGDLNCIAGATSRNG-AFIWDIQKGKIIQRFN 435
           T   T  G++  I AL  +   L  ++G  S++G A  W++ +G  + + +
Sbjct: 525 TLKNTFVGHKAQITALDMSTNYL--VSG--SKDGIAMTWNVAEGSFVGKID 665

 Score = 32.7 bits (73), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 21/84 (25%), Positives = 36/84 (42%)
 Frame = +3

Query: 58  HKKTITAISWCPHNPDLFASSSTDNLVIIWNVAEQKVIAKLDNIKETPACLGWCWNTHDA 117
           HK  ITA+     + +   S S D + + WNVAE   + K+D           C +  +A
Sbjct: 549 HKAQITALD---MSTNYLVSGSKDGIAMTWNVAEGSFVGKID-----------CDDQINA 686

Query: 118 VAFVSQKGPLLIWTISGPDSGVSV 141
           + F  +     +W   G  +G+ +
Sbjct: 687 IKFNIENNKKKVWLFIGTQNGIQI 758
>10264
          Length = 416

 Score = 46.6 bits (109), Expect = 6e-05,   Method: Composition-based stats.
 Identities = 22/79 (27%), Positives = 38/79 (48%)
 Frame = -1

Query: 518 LKVFSGHTARVFHVKWSPLREGILCSGSDDGSVRIWDYTQDACVSTLNGHTAPVRGLMWN 577
           L+  SGH+ RV  + WSP  +  L S   D    +WD  +   ++   GH   +    ++
Sbjct: 266 LRELSGHSQRVTDMSWSPHHDARLVSVGYDAEAFVWDVQKGTALAQFKGHMGRLLTCQFS 87

Query: 578 TEIPYLLISGSWDYTIKVW 596
              P L+++G  D ++ VW
Sbjct: 86  GLDPDLVMTGGSDASVHVW 30

 Score = 33.5 bits (75), Expect = 0.62,   Method: Composition-based stats.
 Identities = 21/81 (25%), Positives = 35/81 (43%)
 Frame = -1

Query: 479 HPAAVFGCDWSQNNKDMIATGCEDKNIRVFYVATSSNQPLKVFSGHTARVFHVKWSPLRE 538
           H   V    WS ++   + +   D    V+ V   +   L  F GH  R+   ++S L  
Sbjct: 248 HSQRVTDMSWSPHHDARLVSVGYDAEAFVWDVQKGT--ALAQFKGHMGRLLTCQFSGLDP 75

Query: 539 GILCSGSDDGSVRIWDYTQDA 559
            ++ +G  D SV +W  +Q A
Sbjct: 74  DLVMTGGSDASVHVWRVSQQA 12

 Score = 33.1 bits (74), Expect = 0.81,   Method: Composition-based stats.
 Identities = 16/58 (27%), Positives = 27/58 (46%), Gaps = 6/58 (10%)
 Frame = -1

Query: 336 YDMGAKKWDFLREL------GHVETIFDCKFKPDDPNVLATASFDGTIKVWDINTLTA 387
           YD  A  WD  +        GH+  +  C+F   DP+++ T   D ++ VW ++   A
Sbjct: 182 YDAEAFVWDVQKGTALAQFKGHMGRLLTCQFSGLDPDLVMTGGSDASVHVWRVSQQAA 9

 Score = 32.7 bits (73), Expect = 0.87,   Method: Composition-based stats.
 Identities = 23/86 (26%), Positives = 37/86 (43%), Gaps = 2/86 (2%)
 Frame = -1

Query: 564 LNGHTAPVRGLMWNTEIPYLLISGSWDYTIKVWDTRGGVCLDTVYDHGADVYGLTCHPS- 622
           L+GH+  V  + W+      L+S  +D    VWD + G  L     H   +  LTC  S 
Sbjct: 257 LSGHSQRVTDMSWSPHHDARLVSVGYDAEAFVWDVQKGTALAQFKGHMGRL--LTCQFSG 84

Query: 623 -RPFTMASCSRDSTVRLWSLIPLITP 647
             P  + +   D++V +W +     P
Sbjct: 83  LDPDLVMTGGSDASVHVWRVSQQAAP 6

 Score = 32.7 bits (73), Expect = 0.97,   Method: Composition-based stats.
 Identities = 15/53 (28%), Positives = 26/53 (49%)
 Frame = -1

Query: 385 LTAVYTSPGNEGVIFALSWAPGDLNCIAGATSRNGAFIWDIQKGKIIQRFNEH 437
           LT++    G+   +  +SW+P     +        AF+WD+QKG  + +F  H
Sbjct: 275 LTSLRELSGHSQRVTDMSWSPHHDARLVSVGYDAEAFVWDVQKGTALAQFKGH 117

 Score = 31.6 bits (70), Expect = 2.0,   Method: Composition-based stats.
 Identities = 12/44 (27%), Positives = 22/44 (50%)
 Frame = -1

Query: 55  MSEHKKTITAISWCPHNPDLFASSSTDNLVIIWNVAEQKVIAKL 98
           +S H + +T +SW PH+     S   D    +W+V +   +A+ 
Sbjct: 257 LSGHSQRVTDMSWSPHHDARLVSVGYDAEAFVWDVQKGTALAQF 126
>20662
          Length = 1220

 Score = 46.6 bits (109), Expect = 7e-05,   Method: Compositional matrix adjust.
 Identities = 33/102 (32%), Positives = 50/102 (49%), Gaps = 4/102 (3%)
 Frame = +2

Query: 544 GSDDGSVRIWDYT-QDACVSTLNG---HTAPVRGLMWNTEIPYLLISGSWDYTIKVWDTR 599
           G D G V +W+   +D   S L+    H      +  N++  + L S S+D+ IKVW+T 
Sbjct: 302 GLDTGGVALWELQDEDKMFSMLSSACEHDDMTASVSINSDXSHYL-SASYDHGIKVWNTD 478

Query: 600 GGVCLDTVYDHGADVYGLTCHPSRPFTMASCSRDSTVRLWSL 641
               L T   H   V+ + CHP+ P    SCS+D  + LW +
Sbjct: 479 L-TSLYTYRAHSDIVWDVQCHPTEPALFLSCSQDGKIVLWDV 601

 Score = 32.0 bits (71), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 58/277 (20%), Positives = 103/277 (37%), Gaps = 6/277 (2%)
 Frame = +2

Query: 323 HVVCCFLD-GGVGLYDMGAKKWDFL---RELGHVETIFDCKFKPDDPNVLATASFDGTIK 378
           H V   LD GGV L+++  +   F        H +         D  + L +AS+D  IK
Sbjct: 287 HKVLVGLDTGGVALWELQDEDKMFSMLSSACEHDDMTASVSINSDXSHYL-SASYDHGIK 463

Query: 379 VWDINTLTAVYTSPGNEGVIFALSWAPGDLNCIAGATSRNGAFIWDIQKGKIIQRFNEHG 438
           VW+ + LT++YT   +  +++ +   P +       +      +WD+++           
Sbjct: 464 VWNTD-LTSLYTYRAHSDIVWDVQCHPTEPALFLSCSQDGKIVLWDVRES---------- 610

Query: 439 KNGIFYIAWSHKDSKRIATCSGDGFCIIRTVDGKLLHKYKHPAAVFGCDWSQNNKDMIAT 498
                      K +  +  CS  GF                P  V    W  N ++M A 
Sbjct: 611 -----------KPATCLPKCSS-GF---------------KPTCV---QWQPNARNMYAV 700

Query: 499 GCEDKNIRVFYVATSSNQPLKVFSGHTARVFHVKWSPLREGILCSGSDD--GSVRIWDYT 556
           G E  ++ V  +     + +  +  H   V  + + P R  +L S  +D          +
Sbjct: 701 GDEGGHVSVQDLRMVVEKNVS-YQSHNRVVTRLAFCPQRPSMLASIGEDCKAVATSVTSS 877

Query: 557 QDACVSTLNGHTAPVRGLMWNTEIPYLLISGSWDYTI 593
             + +   + HT  VRGL W  E   + ++ +WD  I
Sbjct: 878 SSSSLYESSEHTDCVRGLTWAGE--NMFLTSAWDGKI 982
>27475
          Length = 369

 Score = 46.6 bits (109), Expect = 7e-05,   Method: Compositional matrix adjust.
 Identities = 28/77 (36%), Positives = 41/77 (53%), Gaps = 1/77 (1%)
 Frame = +2

Query: 520 VFSGHTARVFHVKWSPLREGILCSGSDDGSVRIWD-YTQDACVSTLNGHTAPVRGLMWNT 578
            F+ HT  V  V WSP RE +  SGS D  +++WD  +  A +  +N H   +  + W+ 
Sbjct: 53  AFTSHTGWVTGVDWSPTREHLFLSGSYDNVLKLWDTRSPKATLYDMNWHEDRILAVDWS- 229

Query: 579 EIPYLLISGSWDYTIKV 595
            IP LL+SG  D  + V
Sbjct: 230 -IPELLLSGGVDNKLHV 277

 Score = 34.7 bits (78), Expect = 0.24,   Method: Compositional matrix adjust.
 Identities = 15/36 (41%), Positives = 22/36 (61%)
 Frame = +2

Query: 564 LNGHTAPVRGLMWNTEIPYLLISGSWDYTIKVWDTR 599
              HT  V G+ W+    +L +SGS+D  +K+WDTR
Sbjct: 56  FTSHTGWVTGVDWSPTREHLFLSGSYDNVLKLWDTR 163

 Score = 30.8 bits (68), Expect = 3.3,   Method: Compositional matrix adjust.
 Identities = 12/40 (30%), Positives = 19/40 (47%)
 Frame = +2

Query: 55 MSEHKKTITAISWCPHNPDLFASSSTDNLVIIWNVAEQKV 94
           + H   +T + W P    LF S S DN++ +W+    K 
Sbjct: 56 FTSHTGWVTGVDWSPTREHLFLSGSYDNVLKLWDTRSPKA 175
>02147
          Length = 1547

 Score = 46.2 bits (108), Expect = 8e-05,   Method: Compositional matrix adjust.
 Identities = 55/242 (22%), Positives = 95/242 (39%), Gaps = 40/242 (16%)
 Frame = +2

Query: 438 GKNGIFYIAWSHKDSKRIATCSGDGFCIIRTVD-GKLLHKYKHPAAVFGCDWSQNNKDMI 496
           G  G  + A  ++++ R AT + D    I   + G+ L  + H   V   D+S +   ++
Sbjct: 167 GHKGAVWGATLNREATRAATGAADFSAKIWDAEKGEELQTFSHKHIVKSVDFSHDGTALL 346

Query: 497 ATGCEDKNIRVFYVATSSNQPLKVFSGHTARVFHVKWSPLREGI-LCSGSDDGSVRIWDY 555
            TG  +K ++VF +  +  +P K F+GHT+ +    +  L +G  + S SDD +VR+W  
Sbjct: 347 -TGSNEKLLKVFDLVNTDAEP-KSFAGHTSNIKGALF--LSDGKRIISASDDKTVRLWSL 514

Query: 556 TQDACVSTLNGHTAPVRGLM----------------------------WNTEIP------ 581
                V  L   T P    +                            +  E P      
Sbjct: 515 ETCQEVQQLTFDTPPTSLTLSPDKNTIIVTHSQNIAFYQADTLREMKKFEAEAPISSASL 694

Query: 582 ----YLLISGSWDYTIKVWDTRGGVCLDTVYDHGADVYGLTCHPSRPFTMASCSRDSTVR 637
                  ++G  D+ +  +D   G  +++   H   V+ +   P      AS S D T+R
Sbjct: 695 HQSERFFVAGGEDFKMYKFDYETGKEIESFKGHFGPVHCVRFSPDGEL-YASGSEDGTLR 871

Query: 638 LW 639
           LW
Sbjct: 872 LW 877

 Score = 40.8 bits (94), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 49/234 (20%), Positives = 94/234 (40%), Gaps = 10/234 (4%)
 Frame = +2

Query: 333 VGLYDMGAKKWDF-----LRELGHVETIFDCKFKPDDPNVLATASFDGTIKVWD-INTLT 386
            G  D  AK WD      L+   H   +    F  D   +L T S +  +KV+D +NT  
Sbjct: 224 TGAADFSAKIWDAEKGEELQTFSHKHIVKSVDFSHDGTALL-TGSNEKLLKVFDLVNTDA 400

Query: 387 AVYTSPGN----EGVIFALSWAPGDLNCIAGATSRNGAFIWDIQKGKIIQRFNEHGKNGI 442
              +  G+    +G +F       D   I  A+      +W ++  + +Q+         
Sbjct: 401 EPKSFAGHTSNIKGALFL-----SDGKRIISASDDKTVRLWSLETCQEVQQLTFDTPPTS 565

Query: 443 FYIAWSHKDSKRIATCSGDGFCIIRTVDGKLLHKYKHPAAVFGCDWSQNNKDMIATGCED 502
             ++    D   I           +    + + K++  A +      Q+ +  +A G   
Sbjct: 566 LTLS---PDKNTIIVTHSQNIAFYQADTLREMKKFEAEAPISSASLHQSERFFVAGG--- 727

Query: 503 KNIRVFYVATSSNQPLKVFSGHTARVFHVKWSPLREGILCSGSDDGSVRIWDYT 556
           ++ +++     + + ++ F GH   V  V++SP  E +  SGS+DG++R+W  T
Sbjct: 728 EDFKMYKFDYETGKEIESFKGHFGPVHCVRFSPDGE-LYASGSEDGTLRLWQTT 886

 Score = 35.4 bits (80), Expect = 0.16,   Method: Compositional matrix adjust.
 Identities = 52/263 (19%), Positives = 94/263 (35%), Gaps = 49/263 (18%)
 Frame = +2

Query: 388 VYTSPGNEGVIFALSWAPGDLNCIAGATSRNGAFIWDIQKGKIIQRFNEHGKNGIFYIAW 447
           + T  G++G ++  +          GA   + A IWD +KG+ +Q F             
Sbjct: 152 IGTFEGHKGAVWGATLNREATRAATGAADFS-AKIWDAEKGEELQTF------------- 289

Query: 448 SHKDSKRIATCSGDGFCIIRTVDGKLLHKYK-------------HPAAVFGCDWSQNNKD 494
           SHK   +    S DG  ++   + KLL  +              H + + G  +  + K 
Sbjct: 290 SHKHIVKSVDFSHDGTALLTGSNEKLLKVFDLVNTDAEPKSFAGHTSNIKGALFLSDGKR 469

Query: 495 MIATGCEDKNIRVFYVATSSNQPLKVFSG-----------------HTARVFHVKWSPLR 537
           +I+   +DK +R++ + T        F                   H+  +   +   LR
Sbjct: 470 IIS-ASDDKTVRLWSLETCQEVQQLTFDTPPTSLTLSPDKNTIIVTHSQNIAFYQADTLR 646

Query: 538 E-------------------GILCSGSDDGSVRIWDYTQDACVSTLNGHTAPVRGLMWNT 578
           E                       +G +D  +  +DY     + +  GH  PV  + ++ 
Sbjct: 647 EMKKFEAEAPISSASLHQSERFFVAGGEDFKMYKFDYETGKEIESFKGHFGPVHCVRFSP 826

Query: 579 EIPYLLISGSWDYTIKVWDTRGG 601
           +   L  SGS D T+++W T  G
Sbjct: 827 D-GELYASGSEDGTLRLWQTTIG 892
>29912
          Length = 510

 Score = 45.8 bits (107), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 45/161 (27%), Positives = 70/161 (43%), Gaps = 6/161 (3%)
 Frame = +3

Query: 393 GNEGVIFALSWAPGDLNCIAGATSRNGAFIWDIQKGKIIQRFNEHGKNGIFYIAWSHKDS 452
           G E  I A+SW   + N +A  TS     +WD+ + K ++    H    +  ++W   +S
Sbjct: 3   GPEEYIGAVSWIK-EGNYLALGTSTGEVQVWDVTQQKKLRTMAGHAAR-VGSLSW---NS 167

Query: 453 KRIATCSGDG---FCIIRTVDGKLLHKYKHPAAVFGCDWSQNNKDMIATGCEDKNIRVF- 508
             +++ S  G      +R  D  +     H   V G  WS + K  +A+G  D  + V+ 
Sbjct: 168 FIVSSGSRSGNIHHHDVRVADHHVGTLSGHSQEVCGLRWSPDGK-YLASGANDNLLCVWP 344

Query: 509 --YVATSSNQPLKVFSGHTARVFHVKWSPLREGILCSGSDD 547
                 +S QPL  FS H A V  + W P +   L SG  D
Sbjct: 345 AQVTGGNSTQPLHTFSQHQAAVKALAWCPWQPSXLASGGGD 467

 Score = 45.8 bits (107), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 36/111 (32%), Positives = 56/111 (50%), Gaps = 2/111 (1%)
 Frame = +3

Query: 531 VKWSPLREG-ILCSGSDDGSVRIWDYTQDACVSTLNGHTAPVRGLMWNTEIPYLLISGSW 589
           V W  ++EG  L  G+  G V++WD TQ   + T+ GH A V  L WN+   +++ SGS 
Sbjct: 27  VSW--IKEGNYLALGTSTGEVQVWDVTQQKKLRTMAGHAARVGSLSWNS---FIVSSGSR 191

Query: 590 DYTIKVWDTR-GGVCLDTVYDHGADVYGLTCHPSRPFTMASCSRDSTVRLW 639
              I   D R     + T+  H  +V GL   P   + +AS + D+ + +W
Sbjct: 192 SGNIHHHDVRVADHHVGTLSGHSQEVCGLRWSPDGKY-LASGANDNLLCVW 341

 Score = 33.1 bits (74), Expect = 0.83,   Method: Compositional matrix adjust.
 Identities = 15/51 (29%), Positives = 26/51 (50%)
 Frame = +3

Query: 35  LAIYIYQLDHRYNEFKLHAIMSEHKKTITAISWCPHNPDLFASSSTDNLVI 85
           L ++  Q+    +   LH   S+H+  + A++WCP  P   AS   D L++
Sbjct: 330 LCVWPAQVTGGNSTQPLH-TFSQHQAAVKALAWCPWQPSXLASGGGDVLIV 479
>04358
          Length = 2430

 Score = 45.8 bits (107), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 59/275 (21%), Positives = 105/275 (38%), Gaps = 26/275 (9%)
 Frame = +1

Query: 350  GHVETIFDCKFKPDDPNVLATASFDGTIKVWDINTLTAVYTSPGNEGVIFALSWAPGDLN 409
            GH + I   +F   DP ++ TAS D T+++WD     +      +       S    D+N
Sbjct: 1414 GHDDVISSIRFLHTDPGLIMTASHDHTVRIWDPRASVSKEVQRFSGEQNTKCSVLSCDVN 1593

Query: 410  ------CIAGATSRNGAFI--WDIQKGKIIQRFNEHGKNGIFYIAWSHKDSKRIATCSGD 461
                  C     S + A++  WD +K K++  + +   + I  + +     K + T S D
Sbjct: 1594 ISDRVLCAGTEMSNDDAYLLFWDRRKDKLLGCYEDSHHDDITQVHFGPTSEKTLLTGSTD 1773

Query: 462  G----FCIIRTV-DGKLLHKYKHPAAVFGCDWSQNNKDMIATGCEDKNIRVFYVATSSN- 515
            G    F +++T  D  L+  Y   A V    W       +       +  V+      + 
Sbjct: 1774 GLVNVFDVMQTTEDDALMSTYNTEATVERAGWCGPQSQQVYAITHMLSWHVWDTEKDEDV 1953

Query: 516  QPL----KVFSGHTARVFHVKWSPLREGI----LCSGSDDGSVRIWDYTQDACVSTLN-- 565
            Q L    +   G     + V   P  +      L +G+  G + + D +    V  +   
Sbjct: 1954 QQLTDLEQKLQGQCQADYLVDCIPANQSTSPPCLVAGTHTGDLHVLDLSDLEEVKVVRSL 2133

Query: 566  --GHTAPVRGLMWNTEIPYLLISGSWDYTIKVWDT 598
              GHT  VR L W+ +    L++G  D  + +W +
Sbjct: 2134 SGGHTDTVRCLHWDKQTQ-TLVTGGEDSMLCLWSS 2235

 Score = 37.4 bits (85), Expect = 0.044,   Method: Compositional matrix adjust.
 Identities = 17/65 (26%), Positives = 36/65 (55%)
 Frame = +1

Query: 538  EGILCSGSDDGSVRIWDYTQDACVSTLNGHTAPVRGLMWNTEIPYLLISGSWDYTIKVWD 597
            + ++ + S +  VR++   + A  +TL GH   +  + +    P L+++ S D+T+++WD
Sbjct: 1330 DSLVAAASSNFMVRLYSRCRLAQTNTLTGHDDVISSIRFLHTDPGLIMTASHDHTVRIWD 1509

Query: 598  TRGGV 602
             R  V
Sbjct: 1510 PRASV 1524
>06576
          Length = 1547

 Score = 45.8 bits (107), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 32/103 (31%), Positives = 46/103 (44%), Gaps = 4/103 (3%)
 Frame = -2

Query: 496  IATGCEDKNIRVFYVATSSNQPLKVFSGHTARVFHVKWSPLREGILCSGSDDGSVRIWDY 555
             A  C+D ++RVF     +     V  GHT  V  V +SP  E  + S  DD + R+W  
Sbjct: 1171 FAAACDDHSVRVFTSDLKTTNKTHVVKGHTDFVNSVTFSPTEEDQVXSTGDDLTCRVWTG 992

Query: 556  T--QDACV--STLNGHTAPVRGLMWNTEIPYLLISGSWDYTIK 594
               QD     S +   TAP   + W+ + P  L+ G  D  I+
Sbjct: 991  KDGQDGRYGESVIFRLTAPGMAVCWHADEPLKLMVGQKDGIIR 863
>37180
          Length = 681

 Score = 45.4 bits (106), Expect = 2e-04,   Method: Composition-based stats.
 Identities = 27/81 (33%), Positives = 43/81 (53%), Gaps = 1/81 (1%)
 Frame = +1

Query: 520 VFSGHTARVFHVKWSPLREGILCSGSDDGSVRIWDYTQDAC-VSTLNGHTAPVRGLMWNT 578
           V +GH   +  V   P +  ++ S S D + R+WD+   A  V+   GHT PV   ++ +
Sbjct: 4   VLNGHDQELSDVHAHPTQRLVVTS-SKDMTFRLWDFRDSALLVNVFQGHTQPVTSAVFAS 180

Query: 579 EIPYLLISGSWDYTIKVWDTR 599
                ++SGS D T++VWD R
Sbjct: 181 GDK--VVSGSDDRTVRVWDMR 237

 Score = 30.4 bits (67), Expect = 4.4,   Method: Composition-based stats.
 Identities = 19/60 (31%), Positives = 32/60 (53%)
 Frame = +1

Query: 495 MIATGCEDKNIRVFYVATSSNQPLKVFSGHTARVFHVKWSPLREGILCSGSDDGSVRIWD 554
           ++ T  +D   R++    S+   + VF GHT  V    ++   +  + SGSDD +VR+WD
Sbjct: 61  LVVTSSKDMTFRLWDFRDSA-LLVNVFQGHTQPVTSAVFASGDK--VVSGSDDRTVRVWD 231
>03156
          Length = 1014

 Score = 45.4 bits (106), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 55/219 (25%), Positives = 95/219 (43%), Gaps = 13/219 (5%)
 Frame = +1

Query: 364 DPNVLATASFDGTIKVWDINTLTAVYTSPGNEGVIFALSWAPGDLNCIAGATSRNGAFIW 423
           D  +L + S D T+++WD+ T   +  +   + ++  + W PG  + I  A       I+
Sbjct: 214 DNTLLCSGSRDNTVRIWDVETGACLRQNNIPQNLVTDVKWLPGS-HLIIQAGEDKEVRIY 390

Query: 424 DIQKGKIIQRFNEHGKNGIFYIAWS---HKDSKRIATCSGDGF-------CIIRTVDGKL 473
           D +   I++ F +       YI  S     D +   TCS +GF        + +  DG +
Sbjct: 391 DSRTLGIVRSFTKKQ-----YIQMSCDVTADGQFCLTCS-NGFGGNGCEATLWQLSDGSI 552

Query: 474 LHKYK-HPAAVFGCDWSQNNKDM--IATGCEDKNIRVFYVATSSNQPLKVFSGHTARVFH 530
            +++K H  A+  C +  +N+DM  IAT   D ++RV+ + T      + F G       
Sbjct: 553 QNEFKGHREAIEACLFLPSNQDMTLIATASRDCSVRVWNMFTKECVCEQNFEGT------ 714

Query: 531 VKWSPLREGILCSGSDDGSVRIWDYTQDACVSTLNGHTA 569
               PL   I      DGSV +  +     V +LNG ++
Sbjct: 715 ---GPLTSMI---AYGDGSVLVGTFNLGVQVMSLNGQSS 813

 Score = 43.5 bits (101), Expect = 6e-04,   Method: Compositional matrix adjust.
 Identities = 25/84 (29%), Positives = 40/84 (47%)
 Frame = +1

Query: 521 FSGHTARVFHVKWSPLREGILCSGSDDGSVRIWDYTQDACVSTLNGHTAPVRGLMWNTEI 580
           ++GH   +  V +     G+  S S D ++++W       +    GH   V  +  NT+ 
Sbjct: 43  WTGHDREITKVCYGASCNGMF-SASRDKTIKMWQRGNSHSIRDFIGHDMVVTAIHLNTD- 216

Query: 581 PYLLISGSWDYTIKVWDTRGGVCL 604
             LL SGS D T+++WD   G CL
Sbjct: 217 NTLLCSGSRDNTVRIWDVETGACL 288

 Score = 42.4 bits (98), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 30/101 (29%), Positives = 49/101 (48%), Gaps = 2/101 (1%)
 Frame = +1

Query: 501 EDKNIRVFYVATSSNQPLKVFSGHTARVFHVKWSPLREGILCSGSDDGSVRIWDYTQDAC 560
            DK I+++    S    ++ F GH   V  +  +     +LCSGS D +VRIWD    AC
Sbjct: 115 RDKTIKMWQRGNS--HSIRDFIGHDMVVTAIHLNT-DNTLLCSGSRDNTVRIWDVETGAC 285

Query: 561 VSTLNGHTAPVRGLMWNTEIP--YLLISGSWDYTIKVWDTR 599
           +   N     V  + W   +P  +L+I    D  ++++D+R
Sbjct: 286 LRQNNIPQNLVTDVKW---LPGSHLIIQAGEDKEVRIYDSR 399
>00561
          Length = 1003

 Score = 45.1 bits (105), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 42/148 (28%), Positives = 72/148 (48%), Gaps = 4/148 (2%)
 Frame = -3

Query: 498 TGCEDKNIRVFYVATSSNQPLKVFSGHTARVFHVKWSPLREGILCSGSDDGSVRIWDYTQ 557
           +G  D+ +R++ +A  + +  + F GHT  V  V +S     I+ SGS D ++++W+ T 
Sbjct: 815 SGSWDQTLRLWDLA--AGKTTRRFEGHTKDVLSVAFSADNRQIV-SGSRDKTIKLWN-TL 648

Query: 558 DACVSTL--NGHTAPVRGLMW--NTEIPYLLISGSWDYTIKVWDTRGGVCLDTVYDHGAD 613
             C  T+  +GHT  V  + +  N   P +++S  WD T+KVW+       +  + H   
Sbjct: 647 AECKFTIQEDGHTDWVSCVRFSPNHSNP-IIVSCGWDRTVKVWNLANCKLKNNHHGHNGY 471

Query: 614 VYGLTCHPSRPFTMASCSRDSTVRLWSL 641
           +  +T  P       S  +DS   LW L
Sbjct: 470 LNTVTVSPDGSL-CTSGGKDSKALLWDL 390

 Score = 43.9 bits (102), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 28/115 (24%), Positives = 55/115 (47%), Gaps = 1/115 (0%)
 Frame = -3

Query: 316 AFSLPPGHVVCCFLDGGVGLYDMGAKKWDFLRELGHVETIFDCKFKPDDPN-VLATASFD 374
           AFS     +V    D  + L++  A+    ++E GH + +   +F P+  N ++ +  +D
Sbjct: 719 AFSADNRQIVSGSRDKTIKLWNTLAECKFTIQEDGHTDWVSCVRFSPNHSNPIIVSCGWD 540

Query: 375 GTIKVWDINTLTAVYTSPGNEGVIFALSWAPGDLNCIAGATSRNGAFIWDIQKGK 429
            T+KVW++          G+ G +  ++ +P    C +G    + A +WD+  GK
Sbjct: 539 RTVKVWNLANCKLKNNHHGHNGYLNTVTVSPDGSLCTSGGKD-SKALLWDLNDGK 378

 Score = 42.7 bits (99), Expect = 9e-04,   Method: Compositional matrix adjust.
 Identities = 31/115 (26%), Positives = 54/115 (46%), Gaps = 6/115 (5%)
 Frame = -3

Query: 534 SPLREGILCSGSDDGSVRIWDYTQDACVS------TLNGHTAPVRGLMWNTEIPYLLISG 587
           +P     + S S D ++ +W  T+D   +       L GH+  +  ++ +++  Y L SG
Sbjct: 986 NPKDPDTIISASRDKTLIVWKLTRDEDTNYGYPQKRLYGHSHFISDVVLSSDGNYAL-SG 810

Query: 588 SWDYTIKVWDTRGGVCLDTVYDHGADVYGLTCHPSRPFTMASCSRDSTVRLWSLI 642
           SWD T+++WD   G        H  DV  +         + S SRD T++LW+ +
Sbjct: 809 SWDQTLRLWDLAAGKTTRRFEGHTKDVLSVAFSADN-RQIVSGSRDKTIKLWNTL 648
>25880
          Length = 423

 Score = 45.1 bits (105), Expect = 2e-04,   Method: Composition-based stats.
 Identities = 25/88 (28%), Positives = 45/88 (51%)
 Frame = +2

Query: 469 VDGKLLHKYKHPAAVFGCDWSQNNKDMIATGCEDKNIRVFYVATSSNQPLKVFSGHTARV 528
           V G  +H ++H   V    +  N+ + I TG  +K +RVF +     +P +++ GHT  +
Sbjct: 23  VSGAEIHSFQHKHIVKSVAFD-NSSENIVTGSNEKLVRVFNLEQPDAEP-ELYGGHTGAI 196

Query: 529 FHVKWSPLREGILCSGSDDGSVRIWDYT 556
                   +  +  SGS+DG++R+W  T
Sbjct: 197 --------KRALYASGSEDGTLRLWQTT 256
>01327
          Length = 2215

 Score = 44.7 bits (104), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 55/219 (25%), Positives = 95/219 (43%), Gaps = 13/219 (5%)
 Frame = +3

Query: 364 DPNVLATASFDGTIKVWDINTLTAVYTSPGNEGVIFALSWAPGDLNCIAGATSRNGAFIW 423
           D  +L + S D T+++WD+ T   +  +   + ++  + W PG  + I  A       I+
Sbjct: 324 DNTLLCSGSRDNTVRIWDVETGACLRQNNIPQNLVTDVKWLPGS-HLIIQAGEDKEVRIY 500

Query: 424 DIQKGKIIQRFNEHGKNGIFYIAWS---HKDSKRIATCSGDGF-------CIIRTVDGKL 473
           D +   I++ F +       YI  S     D +   TCS +GF        + +  DG +
Sbjct: 501 DSRTLGIVRSFTKKQ-----YIQMSCDVTADGQFCLTCS-NGFGGNGCEATLWQLSDGSI 662

Query: 474 LHKYK-HPAAVFGCDWSQNNKDM--IATGCEDKNIRVFYVATSSNQPLKVFSGHTARVFH 530
            +++K H  A+  C +  +N+DM  IAT   D ++RV+ + T      + F G       
Sbjct: 663 QNEFKGHREAIEACLFLPSNQDMTLIATASRDCSVRVWNMFTKECVCEQNFEGT------ 824

Query: 531 VKWSPLREGILCSGSDDGSVRIWDYTQDACVSTLNGHTA 569
               PL   I      DGSV +  +     V +LNG ++
Sbjct: 825 ---GPLTSMI---AYGDGSVLVGTFNLGVQVMSLNGQSS 923

 Score = 43.1 bits (100), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 25/84 (29%), Positives = 40/84 (47%)
 Frame = +3

Query: 521 FSGHTARVFHVKWSPLREGILCSGSDDGSVRIWDYTQDACVSTLNGHTAPVRGLMWNTEI 580
           ++GH   +  V +     G+  S S D ++++W       +    GH   V  +  NT+ 
Sbjct: 153 WTGHDREITKVCYGASCNGMF-SASRDKTIKMWQRGNSHSIRDFIGHDMVVTAIHLNTD- 326

Query: 581 PYLLISGSWDYTIKVWDTRGGVCL 604
             LL SGS D T+++WD   G CL
Sbjct: 327 NTLLCSGSRDNTVRIWDVETGACL 398

 Score = 42.4 bits (98), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 30/101 (29%), Positives = 49/101 (48%), Gaps = 2/101 (1%)
 Frame = +3

Query: 501 EDKNIRVFYVATSSNQPLKVFSGHTARVFHVKWSPLREGILCSGSDDGSVRIWDYTQDAC 560
            DK I+++    S    ++ F GH   V  +  +     +LCSGS D +VRIWD    AC
Sbjct: 225 RDKTIKMWQRGNS--HSIRDFIGHDMVVTAIHLNT-DNTLLCSGSRDNTVRIWDVETGAC 395

Query: 561 VSTLNGHTAPVRGLMWNTEIP--YLLISGSWDYTIKVWDTR 599
           +   N     V  + W   +P  +L+I    D  ++++D+R
Sbjct: 396 LRQNNIPQNLVTDVKW---LPGSHLIIQAGEDKEVRIYDSR 509

 Score = 38.5 bits (88), Expect = 0.018,   Method: Compositional matrix adjust.
 Identities = 34/123 (27%), Positives = 49/123 (39%), Gaps = 3/123 (2%)
 Frame = +3

Query: 533 WSPLRE---GILCSGSDDGSVRIWDYTQDACVSTLNGHTAPVRGLMWNTEIPYLLISGSW 589
           WS  R    G+  SGS D SV ++DY          GH   +  + +      +  S S 
Sbjct: 51  WSA*RSIQPGLCLSGSKDKSVVLYDYQNGRLEDRWTGHDREITKVCYGASCNGMF-SASR 227

Query: 590 DYTIKVWDTRGGVCLDTVYDHGADVYGLTCHPSRPFTMASCSRDSTVRLWSLIPLITPLQ 649
           D TIK+W       +     H   V  +  +      + S SRD+TVR+W +       Q
Sbjct: 228 DKTIKMWQRGNSHSIRDFIGHDMVVTAIHLNTDNTL-LCSGSRDNTVRIWDVETGACLRQ 404

Query: 650 INI 652
            NI
Sbjct: 405 NNI 413
>31474
          Length = 403

 Score = 43.1 bits (100), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 36/113 (31%), Positives = 54/113 (47%), Gaps = 5/113 (4%)
 Frame = -3

Query: 510 VATSSNQPLKVFSGHTARVFHVKWSPLREGILCSGSDDGSVRIWDYTQD--ACVSTL-NG 566
           +A ++ + +   S H    + V W+P    +L S   D  ++IW    D   C STL + 
Sbjct: 350 MAMATLEEVCCLSAHDEHAWCVAWNPTGT-LLASCGSDKIIKIWGKEGDNWVCKSTLTDA 174

Query: 567 HTAPVRGLMWNTEIPYLLISGSWDYTIKVWDTRGG--VCLDTVYDHGADVYGL 617
           HT  VR L W+    YL  S S+D T  VW  +GG   C+ T+  H  +V  +
Sbjct: 173 HTRTVRSLGWSPCGNYL-SSASFDATTAVWSRKGGEFECIATLEGHENEVKAV 18

 Score = 30.8 bits (68), Expect = 3.9,   Method: Compositional matrix adjust.
 Identities = 18/55 (32%), Positives = 26/55 (47%), Gaps = 2/55 (3%)
 Frame = -3

Query: 524 HTARVFHVKWSPLREGILCSGSDDGSVRIWDYT--QDACVSTLNGHTAPVRGLMW 576
           HT  V  + WSP     L S S D +  +W     +  C++TL GH   V+ + W
Sbjct: 173 HTRTVRSLGWSPCGN-YLSSASFDATTAVWSRKGGEFECIATLEGHENEVKAVAW 12

 Score = 29.6 bits (65), Expect = 8.0,   Method: Compositional matrix adjust.
 Identities = 18/56 (32%), Positives = 27/56 (48%), Gaps = 2/56 (3%)
 Frame = -3

Query: 351 HVETIFDCKFKPDDPNVLATASFDGTIKVWDI--NTLTAVYTSPGNEGVIFALSWA 404
           H  T+    + P   N L++ASFD T  VW         + T  G+E  + A++WA
Sbjct: 173 HTRTVRSLGWSPCG-NYLSSASFDATTAVWSRKGGEFECIATLEGHENEVKAVAWA 9
>12960
          Length = 550

 Score = 42.4 bits (98), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 26/82 (31%), Positives = 39/82 (47%)
 Frame = +2

Query: 518 LKVFSGHTARVFHVKWSPLREGILCSGSDDGSVRIWDYTQDACVSTLNGHTAPVRGLMWN 577
           LK + GH   V   + S     I CSG  D +V ++D      +     H   V  + +N
Sbjct: 278 LKTYIGHGHEVLDAQGSGDNSQI-CSGGIDKTVVLFDVASGQALRKYRDHAGTVNCVKFN 454

Query: 578 TEIPYLLISGSWDYTIKVWDTR 599
            E   +++SGS D T++ WDTR
Sbjct: 455 EE-STVILSGSLDNTVRAWDTR 517
>05393
          Length = 904

 Score = 42.0 bits (97), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 35/146 (23%), Positives = 63/146 (43%), Gaps = 17/146 (11%)
 Frame = +1

Query: 513 SSNQPLKVFSGHTARVFHVKWS--------------PLREGILCSGSDDGSVRIWDYTQD 558
           S +  +KV    +A   H  W+              PL+   L + +D G V  +D   +
Sbjct: 22  SFDNTVKVVDCRSAETCHKSWTVEGEVEKAVWNHHNPLQ---LLACTDKGMVYCFDIRHE 192

Query: 559 ACVSTLNGHTAPVRGLMWNTEIPYLLISGSWDYTIKVWDTRGGVCLDTVYDHG---ADVY 615
             V ++  H++ V G+  +++IP L+I+ S D T+KVWD +       V+       +++
Sbjct: 193 KPVFSVGAHSSCVTGVCLSSQIPGLMITTSEDKTMKVWDIQDDK-PTHVFSRNLKMKELH 369

Query: 616 GLTCHPSRPFTMASCSRDSTVRLWSL 641
              C P  PF  A        ++W +
Sbjct: 370 CTGCCPEAPFVFAVGGGRREPKVWDI 447
>17266
          Length = 480

 Score = 41.6 bits (96), Expect = 0.002,   Method: Composition-based stats.
 Identities = 20/58 (34%), Positives = 33/58 (56%)
 Frame = -1

Query: 584 LISGSWDYTIKVWDTRGGVCLDTVYDHGADVYGLTCHPSRPFTMASCSRDSTVRLWSL 641
            +SG+ D + K+WD R G+C  T   H +D+  +T  P+     A+ S D+T RL+ +
Sbjct: 414 FVSGACDASAKLWDVRDGMCKQTFSGHESDINAITYFPN-GHAFATGSDDATCRLFDI 244

 Score = 35.0 bits (79), Expect = 0.19,   Method: Composition-based stats.
 Identities = 22/78 (28%), Positives = 38/78 (48%), Gaps = 2/78 (2%)
 Frame = -1

Query: 543 SGSDDGSVRIWDYTQDACVSTLNGHTAPVRGLMWNTEIP--YLLISGSWDYTIKVWDTRG 600
           SG+ D S ++WD     C  T +GH + +  +   T  P  +   +GS D T +++D R 
Sbjct: 408 SGACDASAKLWDVRDGMCKQTFSGHESDINAI---TYFPNGHAFATGSDDATCRLFDIRA 238

Query: 601 GVCLDTVYDHGADVYGLT 618
              +  +Y H   + G+T
Sbjct: 237 DQEIG-MYSHDNIICGIT 187

 Score = 31.2 bits (69), Expect = 2.9,   Method: Compositional matrix adjust.
 Identities = 27/100 (27%), Positives = 43/100 (43%), Gaps = 1/100 (1%)
 Frame = -1

Query: 492 NKDMIATGCEDKNIRVFYVATSSNQPLKVFSGHTARVFHVKWSPLREG-ILCSGSDDGSV 550
           N    ATG +D   R+F +   ++Q + ++S           +  + G +L  G DD + 
Sbjct: 300 NGHAFATGSDDATCRLFDI--RADQEIGMYSHDNIICGITSVAFSKSGRLLLGGYDDFNC 127

Query: 551 RIWDYTQDACVSTLNGHTAPVRGLMWNTEIPYLLISGSWD 590
            IWD  +      L GH   V   +  TE    + +GSWD
Sbjct: 126 NIWDVLKQERTGVLAGHDNRVS-CLGVTEDGSAVATGSWD 10
>17598
          Length = 875

 Score = 41.6 bits (96), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 23/80 (28%), Positives = 39/80 (48%)
 Frame = +1

Query: 563 TLNGHTAPVRGLMWNTEIPYLLISGSWDYTIKVWDTRGGVCLDTVYDHGADVYGLTCHPS 622
           TL GH+  V  +  + +  Y+L S SWD T+++WD + G        H  D   +   P 
Sbjct: 106 TLQGHSHFVSDVSLSADSRYVL-SSSWDATLRLWDIKKGNTTRRFISHTRDALAVAFSPD 282

Query: 623 RPFTMASCSRDSTVRLWSLI 642
               +AS  RD  +++W+ +
Sbjct: 283 NR-QIASGGRDKALKIWNTV 339

 Score = 40.8 bits (94), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 36/126 (28%), Positives = 58/126 (46%), Gaps = 3/126 (2%)
 Frame = +1

Query: 519 KVFSGHTARVFHVKWSPLREGILCSGSDDGSVRIWDYTQDACVSTL--NGHTAPVRGLMW 576
           + F  HT     V +SP    I  SG  D +++IW+ T   C  T+  N H   V  + +
Sbjct: 229 RRFISHTRDALAVAFSPDNRQI-ASGGRDKALKIWN-TVGECKFTVDANSHQDWVTCVKF 402

Query: 577 NTEIPY-LLISGSWDYTIKVWDTRGGVCLDTVYDHGADVYGLTCHPSRPFTMASCSRDST 635
           + +    L++S S D TIKVWD +      T   H   +  +     + + +AS S+D  
Sbjct: 403 HQDAKSPLVVSASMDKTIKVWDNQTMTLKHTFVGHKTQINAIDL-ALKTYYLASGSKDGI 579

Query: 636 VRLWSL 641
           V  W++
Sbjct: 580 VMTWNI 597

 Score = 36.6 bits (83), Expect = 0.068,   Method: Compositional matrix adjust.
 Identities = 27/87 (31%), Positives = 45/87 (51%), Gaps = 2/87 (2%)
 Frame = +1

Query: 351 HVETIFDCKFKPDDPN-VLATASFDGTIKVWDINTLTAVYTSPGNEGVIFALSWAPGDLN 409
           H + +   KF  D  + ++ +AS D TIKVWD  T+T  +T  G++  I A+  A     
Sbjct: 373 HQDWVTCVKFHQDAKSPLVVSASMDKTIKVWDNQTMTLKHTFVGHKTQINAIDLALKTYY 552

Query: 410 CIAGATSRNG-AFIWDIQKGKIIQRFN 435
             +G  S++G    W+IQ G  + + +
Sbjct: 553 LASG--SKDGIVMTWNIQNGTFLGKID 627
>27270
          Length = 1078

 Score = 41.6 bits (96), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 30/117 (25%), Positives = 52/117 (44%), Gaps = 4/117 (3%)
 Frame = +2

Query: 330 DGGVGLYDMGAKKWDFLRELGHVETIFDCKFKPDDPNVLATASFDGTIKVWDINTLTAV- 388
           DG VGLY +    +  +   GH + + D  ++ D    L ++S DG +  W++NTL  + 
Sbjct: 206 DGSVGLYSVETHTYTHMLNKGHSKAVTDMCWRADG-RTLYSSSLDGHVIGWNVNTLHMIE 382

Query: 389 ---YTSPGNEGVIFALSWAPGDLNCIAGATSRNGAFIWDIQKGKIIQRFNEHGKNGI 442
               TS  + GV      +   L      T+ +   +WD+    ++Q F+ H    I
Sbjct: 383 KWKATSGRHHGVHCVCLCSSSRL-----LTADHTIKMWDLTTKNVLQEFSGHSTEVI 538
>18981
          Length = 407

 Score = 41.2 bits (95), Expect = 0.002,   Method: Composition-based stats.
 Identities = 27/107 (25%), Positives = 49/107 (45%), Gaps = 1/107 (0%)
 Frame = -2

Query: 536 LREGILCSGSDDGSVRIWDYTQDACVSTLNGHTAPVRGL-MWNTEIPYLLISGSWDYTIK 594
           L + ++ S + D ++R+W       + TL GH   V  + ++   +    +SGSWD T+ 
Sbjct: 394 LLDNMIISAATDRTLRVWCLKNTCLLHTLRGHNDDVECVCIYGRRV----VSGSWDKTLI 227

Query: 595 VWDTRGGVCLDTVYDHGADVYGLTCHPSRPFTMASCSRDSTVRLWSL 641
           VW+   G  +  ++ H   +  +     +     S S D  VR W+L
Sbjct: 226 VWEVDTGRPVHQLHGHTEAITAVQFDEGKA---VSGSADGDVRTWAL 95

 Score = 39.3 bits (90), Expect = 0.010,   Method: Composition-based stats.
 Identities = 27/86 (31%), Positives = 42/86 (48%), Gaps = 1/86 (1%)
 Frame = -2

Query: 496 IATGCEDKNIRVFYVATSSNQPLKVFSGHTARVFHVKWSPLREGILCSGSDDGSVRIWDY 555
           + +G  DK + V+ V T   +P+    GHT  +  V++    EG   SGS DG VR W  
Sbjct: 259 VVSGSWDKTLIVWEVDTG--RPVHQLHGHTEAITAVQFD---EGKAVSGSADGDVRTWAL 95

Query: 556 TQDACVSTL-NGHTAPVRGLMWNTEI 580
               C+ T+  G    V  +++N E+
Sbjct: 94  DTGQCLLTMTTGQDIEVYCVVYNQEV 17

 Score = 35.0 bits (79), Expect = 0.20,   Method: Composition-based stats.
 Identities = 30/114 (26%), Positives = 51/114 (44%)
 Frame = -2

Query: 494 DMIATGCEDKNIRVFYVATSSNQPLKVFSGHTARVFHVKWSPLREGILCSGSDDGSVRIW 553
           +MI +   D+ +RV+ +  +    L    GH   V  V     R   + SGS D ++ +W
Sbjct: 385 NMIISAATDRTLRVWCLKNTC--LLHTLRGHNDDVECVCIYGRR---VVSGSWDKTLIVW 221

Query: 554 DYTQDACVSTLNGHTAPVRGLMWNTEIPYLLISGSWDYTIKVWDTRGGVCLDTV 607
           +      V  L+GHT  +  + ++       +SGS D  ++ W    G CL T+
Sbjct: 220 EVDTGRPVHQLHGHTEAITAVQFDEGKA---VSGSADGDVRTWALDTGQCLLTM 68
>34005
          Length = 456

 Score = 41.2 bits (95), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 31/85 (36%), Positives = 40/85 (47%), Gaps = 5/85 (5%)
 Frame = +1

Query: 528 VFHVKWSPLREGILCSGSDDGSVRIWDYTQDACV---STLNGHTAPVRGLMWNTEIPYLL 584
           V  + WSP     L SGS+D SV IWD T    V    TL  H A V+ + W      +L
Sbjct: 121 VCGLSWSP-DATFLASGSNDNSVNIWDSTLGMDVPPLHTLTSHQAAVKAVAWCPWQTRML 297

Query: 585 ISGSW--DYTIKVWDTRGGVCLDTV 607
            +G    D  I+ W+T  G C+  V
Sbjct: 298 ATGGGTNDRHIRFWNTNTGACVKAV 372

 Score = 39.3 bits (90), Expect = 0.011,   Method: Compositional matrix adjust.
 Identities = 24/89 (26%), Positives = 42/89 (47%), Gaps = 3/89 (3%)
 Frame = +1

Query: 480 PAAVFGCDWSQNNKDMIATGCEDKNIRVFYVATSSN-QPLKVFSGHTARVFHVKWSPLRE 538
           P  V G  WS +    +A+G  D ++ ++      +  PL   + H A V  V W P + 
Sbjct: 112 PQEVCGLSWSPD-ATFLASGSNDNSVNIWDSTLGMDVPPLHTLTSHQAAVKAVAWCPWQT 288

Query: 539 GILCSG--SDDGSVRIWDYTQDACVSTLN 565
            +L +G  ++D  +R W+    ACV  ++
Sbjct: 289 RMLATGGGTNDRHIRFWNTNTGACVKAVD 375

 Score = 30.8 bits (68), Expect = 3.5,   Method: Compositional matrix adjust.
 Identities = 16/63 (25%), Positives = 29/63 (46%), Gaps = 2/63 (3%)
 Frame = +1

Query: 51  LHAIMSEHKKTITAISWCPHNPDLFAS--SSTDNLVIIWNVAEQKVIAKLDNIKETPACL 108
           LH + S H+  + A++WCP    + A+   + D  +  WN      +  +D   +  + L
Sbjct: 226 LHTLTS-HQAAVKAVAWCPWQTRMLATGGGTNDRHIRFWNTNTGACVKAVDTQSQVCSVL 402

Query: 109 GWC 111
            WC
Sbjct: 403 -WC 408
>19498
          Length = 903

 Score = 40.4 bits (93), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 31/112 (27%), Positives = 50/112 (44%), Gaps = 6/112 (5%)
 Frame = -1

Query: 479 HPAAVFGCDWSQNNKDMIATGCEDKNIRVFYVATSSNQPLKVFSGHTARVFHVKWSPLRE 538
           H   V    WS   +D+    C   N  V + A   ++ + V  GH   V  V W P+  
Sbjct: 612 HAGDVLDLAWSP--QDLWLASCSVDNTIVVWNALKFSEQVAVIRGHAGMVKGVTWDPVGR 439

Query: 539 GILCSGSDDGSVRIW---DYTQDACVSTL---NGHTAPVRGLMWNTEIPYLL 584
             L S SDD ++R+W   D+ ++ CV +     G T  V  L W+ +  +++
Sbjct: 438 -YLASQSDDKTLRVWRTSDWKEETCVKSCFKECGGTTHVLRLNWSPDGNHVV 286
>21105
          Length = 650

 Score = 40.0 bits (92), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 24/104 (23%), Positives = 47/104 (45%), Gaps = 4/104 (3%)
 Frame = +1

Query: 540 ILCSGSDDGSVRIWDYTQDACVSTLNGHTAPVRGLMWNTEIPYLLISGSWDYTIKVWDTR 599
           I  +  +D  +R +D      +  +  H   V  L  +    YLL SGS D +I++W+  
Sbjct: 106 ITITAHEDRHIRFFDNNTGKLIHAMVAHLDSVTSLAVDPNGLYLL-SGSHDCSIRLWNLD 282

Query: 600 GGVCLDTVYDH----GADVYGLTCHPSRPFTMASCSRDSTVRLW 639
              C+  +  H       ++ +  HP +P+ +AS   D+  +++
Sbjct: 283 SKTCVQEITSHRKKFDESIHDVAFHPQKPY-IASAGADALAKVF 411

 Score = 35.0 bits (79), Expect = 0.20,   Method: Compositional matrix adjust.
 Identities = 27/104 (25%), Positives = 48/104 (46%), Gaps = 5/104 (4%)
 Frame = +1

Query: 498 TGCEDKNIRVFYVATSSNQPLKVFSGHTARVFHVKWSPLREGI-LCSGSDDGSVRIWDYT 556
           T  ED++IR F    ++ + +     H   V  +   P   G+ L SGS D S+R+W+  
Sbjct: 115 TAHEDRHIRFF--DNNTGKLIHAMVAHLDSVTSLAVDP--NGLYLLSGSHDCSIRLWNLD 282

Query: 557 QDACVSTLNGHTA----PVRGLMWNTEIPYLLISGSWDYTIKVW 596
              CV  +  H       +  + ++ + PY+  +G+ D   KV+
Sbjct: 283 SKTCVQEITSHRKKFDESIHDVAFHPQKPYIASAGA-DALAKVF 411
>10162
          Length = 1629

 Score = 40.0 bits (92), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 61/269 (22%), Positives = 108/269 (40%), Gaps = 39/269 (14%)
 Frame = +3

Query: 323 HVVCCFLDGG-VGLYDMGAKKWDFLREL-GHVETIFDCKFKPDDPNVLATASFDGTIKVW 380
           HV+     GG V L+ + ++ +  ++ L  H +     K  P+   V    S DG +K+W
Sbjct: 66  HVLLAGTQGGEVWLWQVPSQDYSKMKMLQSHGQPSLCGKILPNGKYVCVGYS-DGVVKLW 242

Query: 381 DINTLTAVYT-----SPGNE-----------------------GVIFALSWAPGDLNCIA 412
           D+ T TAV+T      P  E                         I  +     D   I 
Sbjct: 243 DLKTGTAVHTWQHSVMPEEEMPERNSSDEEDGEEVEVEREEDTVAILCVD-CSADNALIM 419

Query: 413 GATSRNGAFIWDIQKGKIIQRFN-------EHGKNGIFYIAWSHKDSKRIATCSGDGFCI 465
              +   A ++++  GK+   FN       +   N +  +A+    S   AT +  G   
Sbjct: 420 SGCADATAKVFNVSSGKLXSAFNCAASQDSQDKDNSVESVAFC-PVSPYAATATNSGSVQ 596

Query: 466 IRTVDGKLL-HKYKHPAAVFGCDWSQNNKDMIATGCEDKNIRVFYVATSSNQPLKVFSGH 524
           +  +   +  H ++HP  V    WS +   ++ T C D  +RV+   + +++   V +GH
Sbjct: 597 VWDLPTSVARHSFQHPEGVCKLQWSSSTA-LLYTACLDGVMRVWDARSGASKA--VLTGH 767

Query: 525 TARVFHVKWSPLREGI-LCSGSDDGSVRI 552
                 + +   R+G  L SGS+DG+ R+
Sbjct: 768 ARNSCILDFDVTRDGTCLVSGSEDGTARV 854
>33180
          Length = 460

 Score = 32.0 bits (71), Expect(2) = 0.009,   Method: Compositional matrix adjust.
 Identities = 22/77 (28%), Positives = 35/77 (45%)
 Frame = -2

Query: 478 KHPAAVFGCDWSQNNKDMIATGCEDKNIRVFYVATSSNQPLKVFSGHTARVFHVKWSPLR 537
           +H   +F   +S +N +++  G  D  + V+     SNQ       H   V  V ++   
Sbjct: 459 EHSFCIFSLMFSSDNTEIVG-GANDGCLYVY--DRESNQRTLKIDAHDDDVNAVAFADDS 289

Query: 538 EGILCSGSDDGSVRIWD 554
             IL SG DDG  ++WD
Sbjct: 288 SQILYSGGDDGLCKVWD 238

 Score = 26.2 bits (56), Expect(2) = 0.009,   Method: Composition-based stats.
 Identities = 11/17 (64%), Positives = 13/17 (76%)
 Frame = -1

Query: 583 LLISGSWDYTIKVWDTR 599
           LL+S S D TIK+WD R
Sbjct: 142 LLLSNSKDQTIKLWDVR 92
>21921
          Length = 1341

 Score = 39.3 bits (90), Expect = 0.010,   Method: Compositional matrix adjust.
 Identities = 28/101 (27%), Positives = 50/101 (49%)
 Frame = -1

Query: 493 KDMIATGCEDKNIRVFYVATSSNQPLKVFSGHTARVFHVKWSPLREGILCSGSDDGSVRI 552
           +D++    + K++R F     + Q L V+ GHT  V  +   P  +  L SGSDDG++R 
Sbjct: 564 QDLLPKLPKPKDLRPF----PTTQAL-VYKGHTGIVRSICPDPTGQW-LVSGSDDGTIRF 403

Query: 553 WDYTQDACVSTLNGHTAPVRGLMWNTEIPYLLISGSWDYTI 593
           W+ +   C+ TL      V  + WN      +++ + + T+
Sbjct: 402 WEVSSGRCMKTLQVGGC-VTSVAWNPNPSLCVVAATLNTTV 283

 Score = 31.2 bits (69), Expect = 2.7,   Method: Compositional matrix adjust.
 Identities = 22/74 (29%), Positives = 38/74 (51%)
 Frame = -1

Query: 565 NGHTAPVRGLMWNTEIPYLLISGSWDYTIKVWDTRGGVCLDTVYDHGADVYGLTCHPSRP 624
            GHT  VR +  +    +L +SGS D TI+ W+   G C+ T+   G  V  +  +P+  
Sbjct: 492 KGHTGIVRSICPDPTGQWL-VSGSDDGTIRFWEVSSGRCMKTL-QVGGCVTSVAWNPNPS 319

Query: 625 FTMASCSRDSTVRL 638
             + + + ++TV L
Sbjct: 318 LCVVAATLNTTVLL 277
>00825
          Length = 1821

 Score = 39.3 bits (90), Expect = 0.011,   Method: Compositional matrix adjust.
 Identities = 48/215 (22%), Positives = 81/215 (37%), Gaps = 13/215 (6%)
 Frame = -2

Query: 352  VETIFDCKFKPDDPNVLATASFDGTIKVWDINTLTAVYTSPGNEGVIF----ALSWAPGD 407
            VE++   KF P +  +L  A+ D +I ++D+       ++P  + V+     ALSW P +
Sbjct: 1487 VESVHHVKFNPVETYLLGAAAHDRSILLYDMRG-----SAPLRKVVMKMRTNALSWNPME 1323

Query: 408  LNCIAGATSRNGAFIWDIQKGKIIQRFNEHGKNGIFYIAWSHKDSKRIATCSGDGFCIIR 467
               I  A      + +D++K  +                  H+D                
Sbjct: 1322 AFTITSANEDGNLYTFDMRKLSMPLNM--------------HRD---------------- 1233

Query: 468  TVDGKLLHKYKHPAAVFGCDWSQNNKDMIATGCEDKNIRVFYVATSSNQPLKVFSGHTAR 527
                       H AAV   D+    ++ ++ G  DK IR+F           V  GH+  
Sbjct: 1232 -----------HTAAVMDVDYCPTGREFVSAGY-DKVIRIF----------PVDKGHSRE 1119

Query: 528  VFHVK---------WSPLREGILCSGSDDGSVRIW 553
            V+H K         WS   + I  S SD+ ++R+W
Sbjct: 1118 VYHTKRMQRVGSVVWSRDSKYIF-SASDEMNIRVW 1017

 Score = 35.4 bits (80), Expect = 0.15,   Method: Compositional matrix adjust.
 Identities = 27/112 (24%), Positives = 49/112 (43%)
 Frame = -2

Query: 540  ILCSGSDDGSVRIWDYTQDACVSTLNGHTAPVRGLMWNTEIPYLLISGSWDYTIKVWDTR 599
             + SGS    V +WD  +   + + +     V  + +N    YLL + + D +I ++D R
Sbjct: 1562 FVTSGS---RVDVWDEKRSEPMRSFSWGVESVHHVKFNPVETYLLGAAAHDRSILLYDMR 1392

Query: 600  GGVCLDTVYDHGADVYGLTCHPSRPFTMASCSRDSTVRLWSLIPLITPLQIN 651
            G   L  V         L+ +P   FT+ S + D  +  + +  L  PL ++
Sbjct: 1391 GSAPLRKVV-MKMRTNALSWNPMEAFTITSANEDGNLYTFDMRKLSMPLNMH 1239

 Score = 32.0 bits (71), Expect = 1.7,   Method: Compositional matrix adjust.
 Identities = 22/70 (31%), Positives = 31/70 (44%), Gaps = 2/70 (2%)
 Frame = -2

Query: 586  SGSWDYTIKVWDTRGGVCLDTVYDHGADVYGLTCHPSRPFTMASCSRDSTVRLWSLIP-- 643
            SG+ D  +  W+         V  H   V+G+  H S  +   SC  D T++ WSL P  
Sbjct: 1820 SGACDGELICWNLPKQQMACRVQAHDGIVHGMAAHSSGQYFF-SCGSDKTIKQWSLDPEG 1644

Query: 644  LITPLQINIL 653
             I P  +N L
Sbjct: 1643 TIAPEPVNTL 1614
>26107
          Length = 1338

 Score = 38.1 bits (87), Expect = 0.022,   Method: Compositional matrix adjust.
 Identities = 47/199 (23%), Positives = 82/199 (41%), Gaps = 17/199 (8%)
 Frame = -3

Query: 347  RELGHVETIFDCKFKPDDPNVLATASFDGTIKVWDINTLTAVYTSPGNEGVIFALSWAPG 406
            R   H   +FD  +  +D   L TAS D T+ +WD+ T T V T  G++  + +++  P 
Sbjct: 1102 RWXAHNNAVFDYSWISNDSQCL-TASGDQTVALWDVETTTKVTTFIGHKCSVRSVASCPS 926

Query: 407  D-LNCIAGATSRNGA-FIWDIQKGKIIQRFNEHGKNGIFYIAWSHKDSKRIATCSGDGFC 464
                C +GA  R+G   +WD +    + +  EH              S+    C   G  
Sbjct: 925  SPAQCASGA--RDGHIMLWDSR----VNKKREH-----------QPCSQVHQVCPQSGH- 800

Query: 465  IIRTVDGKLLHKYKHPAAVFG------CDWSQNNKDMIATGCEDK-----NIRVFYVATS 513
              +    + +H+   P  V        C   Q +  +I++G  D      + R +Y  T+
Sbjct: 799  QSKPAKHRRIHRAAGPKGVMDTQQSVTCVLYQTDNLIISSGANDGCVKMWDTRKWYTNTT 620

Query: 514  SNQPLKV----FSGHTARV 528
            ++ P+ V    + GH  R+
Sbjct: 619  TSLPVPVHTFDYPGHMRRL 563

 Score = 35.8 bits (81), Expect = 0.13,   Method: Compositional matrix adjust.
 Identities = 24/79 (30%), Positives = 33/79 (41%)
 Frame = -3

Query: 521  FSGHTARVFHVKWSPLREGILCSGSDDGSVRIWDYTQDACVSTLNGHTAPVRGLMWNTEI 580
            +  H   VF   W       L + S D +V +WD      V+T  GH   VR +      
Sbjct: 1099 WXAHNNAVFDYSWISNDSQCL-TASGDQTVALWDVETTTKVTTFIGHKCSVRSVASCPSS 923

Query: 581  PYLLISGSWDYTIKVWDTR 599
            P    SG+ D  I +WD+R
Sbjct: 922  PAQCASGARDGHIMLWDSR 866
>25400
          Length = 462

 Score = 37.4 bits (85), Expect = 0.041,   Method: Composition-based stats.
 Identities = 23/58 (39%), Positives = 31/58 (53%), Gaps = 3/58 (5%)
 Frame = +3

Query: 543 SGSDDGSVRIWDYTQDACVSTLNG-HTAPVRGLMWNTEIPYL--LISGSWDYTIKVWD 597
           SG   G++ I+D      V  L+G H + VR + W+   PY   LIS SWD T+  WD
Sbjct: 12  SGCATGTILIYDLLTGRVVRKLDGGHRSCVRDVSWH---PYTNTLISSSWDGTVGKWD 176

 Score = 29.3 bits (64), Expect = 9.9,   Method: Composition-based stats.
 Identities = 20/60 (33%), Positives = 28/60 (46%)
 Frame = +3

Query: 496 IATGCEDKNIRVFYVATSSNQPLKVFSGHTARVFHVKWSPLREGILCSGSDDGSVRIWDY 555
           + +GC    I ++ + T      K+  GH + V  V W P     L S S DG+V  WDY
Sbjct: 6   VYSGCATGTILIYDLLTG-RVVRKLDGGHRSCVRDVSWHPY-TNTLISSSWDGTVGKWDY 179
>19863
          Length = 502

 Score = 37.0 bits (84), Expect = 0.051,   Method: Compositional matrix adjust.
 Identities = 23/67 (34%), Positives = 36/67 (53%), Gaps = 5/67 (7%)
 Frame = +1

Query: 584 LISGSWDYTIKVWDTRGGVCLDTVYDHGADVYGLTCHPSRPFTMASCSRDSTVRLWSL-- 641
           L+SGS D +I VWD   GV    +  H   V  +     + + + SCS D+TVR+W++  
Sbjct: 16  LVSGSSDMSIVVWDVENGVQKLRLQGHAGWVNDVHFSQDQCWLL-SCSNDNTVRIWNIEE 192

Query: 642 ---IPLI 645
              IP++
Sbjct: 193 SDQIPIV 213

 Score = 33.1 bits (74), Expect = 0.72,   Method: Compositional matrix adjust.
 Identities = 29/111 (26%), Positives = 47/111 (42%), Gaps = 4/111 (3%)
 Frame = +1

Query: 541 LCSGSDDGSVRIWDYTQDACVSTLNGHTAPVRGLMWNTEIPYLLISGSWDYTIKVWDTRG 600
           L SGS D S+ +WD         L GH   V  + ++ +  +LL S S D T+++W+   
Sbjct: 16  LVSGSSDMSIVVWDVENGVQKLRLQGHAGWVNDVHFSQDQCWLL-SCSNDNTVRIWNIEE 192

Query: 601 GVCLDTVYDHGADVYGLTCHP----SRPFTMASCSRDSTVRLWSLIPLITP 647
              +  V +H     GL         +PF+M+       V +     L +P
Sbjct: 193 SDQIPIVMEHKR-AQGLKVTKCSKCGKPFSMSEVENFKDVTVCVFCRLQSP 342
>27681
          Length = 465

 Score = 37.0 bits (84), Expect = 0.052,   Method: Compositional matrix adjust.
 Identities = 29/88 (32%), Positives = 41/88 (46%), Gaps = 15/88 (17%)
 Frame = +2

Query: 528 VFHVKWSPLREGILCSGSDDGSVRIWDYTQDA-----------CVSTLNGHTAP----VR 572
           VF   W+P  + +L SGS D + RIW+ T +            C+    G   P    V 
Sbjct: 2   VFICAWNPTND-LLASGSGDSTARIWNMTSETPNNANQLVLRHCIQK-GGTEVPSNKDVT 175

Query: 573 GLMWNTEIPYLLISGSWDYTIKVWDTRG 600
            L WN+E   LL +GS+D   ++W T G
Sbjct: 176 SLDWNSE-GTLLATGSYDGYARLWRTDG 256

 Score = 29.6 bits (65), Expect = 9.0,   Method: Composition-based stats.
 Identities = 14/35 (40%), Positives = 18/35 (51%)
 Frame = +3

Query: 569 APVRGLMWNTEIPYLLISGSWDYTIKVWDTRGGVC 603
           AP+  L WN    Y+L +G  D T  +WD   G C
Sbjct: 288 APIFALKWNKRGNYILSAGV-DKTTIIWDASSGSC 389
>15745
          Length = 1183

 Score = 36.6 bits (83), Expect = 0.060,   Method: Compositional matrix adjust.
 Identities = 37/138 (26%), Positives = 55/138 (39%), Gaps = 11/138 (7%)
 Frame = +2

Query: 531 VKWSPLREGILCSGSDDGSVRIWDYT------QDACVSTLNGHTAP-VRGLMWNTEIPYL 583
           + W P  +     G  +  V +WD        Q   + TL G   P +    WN      
Sbjct: 446 ILWHPTGDSQTVLGVCEDRVIMWDLNVASSSAQQTDMITLEGKGQPRLTCGRWNPHHNCA 625

Query: 584 LISGSWDYTIKVWDTRGGVCLDTVYD----HGADVYGLTCHPSRPFTMASCSRDSTVRLW 639
            I+ + + TI+ WD R        Y     HG  V  L  +P+R + +ASC  D  V+ W
Sbjct: 626 QIATANEATIRGWDLRSK---QQTYQMEGAHGQLVRDLDFNPNRQYYLASCGDDCRVKFW 796

Query: 640 SLIPLITPLQINILADRS 657
                  PL+  +L+D S
Sbjct: 797 DTRNCSEPLK--VLSDHS 844
>21960
          Length = 756

 Score = 36.6 bits (83), Expect = 0.073,   Method: Compositional matrix adjust.
 Identities = 23/65 (35%), Positives = 35/65 (53%), Gaps = 1/65 (1%)
 Frame = +1

Query: 533 WSPLREGILCSGSDDGSVRIWDYTQDACVSTLNGHTAPVRG-LMWNTEIPYLLISGSWDY 591
           + P  E I+ SGSDDG++  WD   +A  + + G  A V   L  +  +P L  SG  D+
Sbjct: 388 FGPHSEHII-SGSDDGNIFYWDKNTEAVTNFMKGDDAGVVNCLEQHPTMPVLATSG-LDH 561

Query: 592 TIKVW 596
            +K+W
Sbjct: 562 NVKIW 576
>15780
          Length = 735

 Score = 35.8 bits (81), Expect = 0.11,   Method: Compositional matrix adjust.
 Identities = 21/60 (35%), Positives = 31/60 (51%)
 Frame = -1

Query: 582 YLLISGSWDYTIKVWDTRGGVCLDTVYDHGADVYGLTCHPSRPFTMASCSRDSTVRLWSL 641
           YL  +G+ D+T+ VWD   G  +  +  H   VY L C       +AS   D+++RLW L
Sbjct: 732 YLSTAGA-DHTVIVWDIASGTAVAHLTAHTDTVYAL-CFSRDGTVLASGGMDNSIRLWDL 559

 Score = 32.3 bits (72), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 18/57 (31%), Positives = 29/57 (50%)
 Frame = -1

Query: 541 LCSGSDDGSVRIWDYTQDACVSTLNGHTAPVRGLMWNTEIPYLLISGSWDYTIKVWD 597
           L +   D +V +WD      V+ L  HT  V  L ++ +   +L SG  D +I++WD
Sbjct: 729 LSTAGADHTVIVWDIASGTAVAHLTAHTDTVYALCFSRD-GTVLASGGMDNSIRLWD 562

 Score = 31.2 bits (69), Expect = 2.8,   Method: Compositional matrix adjust.
 Identities = 19/60 (31%), Positives = 31/60 (51%)
 Frame = -1

Query: 368 LATASFDGTIKVWDINTLTAVYTSPGNEGVIFALSWAPGDLNCIAGATSRNGAFIWDIQK 427
           L+TA  D T+ VWDI + TAV     +   ++AL ++  D   +A     N   +WD+ +
Sbjct: 729 LSTAGADHTVIVWDIASGTAVAHLTAHTDTVYALCFSR-DGTVLASGGMDNSIRLWDLAR 553
>07781
          Length = 1269

 Score = 35.8 bits (81), Expect = 0.12,   Method: Compositional matrix adjust.
 Identities = 29/87 (33%), Positives = 39/87 (44%), Gaps = 3/87 (3%)
 Frame = -2

Query: 575 MWNTEIPYLLISGSWDYTIKVWDTRGG---VCLDTVYDHGADVYGLTCHPSRPFTMASCS 631
            WNTE+ Y   SGS D  +KVWD R G   V  ++ +  G  V  +   P R   +A  S
Sbjct: 764 QWNTELIY---SGSDDCKLKVWDLRVGTTPVLTNSRFTMG--VTSIQSCPQREHLLAVGS 600

Query: 632 RDSTVRLWSLIPLITPLQINILADRSW 658
            D  +RL+    +  PL    L    W
Sbjct: 599 YDENLRLFDTRHMRQPLSTTALEGGVW 519

 Score = 33.9 bits (76), Expect = 0.40,   Method: Compositional matrix adjust.
 Identities = 24/97 (24%), Positives = 46/97 (47%), Gaps = 1/97 (1%)
 Frame = -2

Query: 504 NIRVFYVATSSNQPLKVFSGHTARVFHVKWSPLREGILCSGSDDGSVRIWDYTQDAC-VS 562
           N+ VF V +++ +    +  H    +   +      ++ SGSDD  +++WD       V 
Sbjct: 857 NLTVFEVESTTVRETSQWRAHDFEAWICAFDQWNTELIYSGSDDCKLKVWDLRVGTTPVL 678

Query: 563 TLNGHTAPVRGLMWNTEIPYLLISGSWDYTIKVWDTR 599
           T +  T  V  +    +  +LL  GS+D  ++++DTR
Sbjct: 677 TNSRFTMGVTSIQSCPQREHLLAVGSYDENLRLFDTR 567

 Score = 33.1 bits (74), Expect = 0.81,   Method: Compositional matrix adjust.
 Identities = 25/118 (21%), Positives = 47/118 (39%), Gaps = 14/118 (11%)
 Frame = -2

Query: 334 GLYDMGAKKWDFLRELGHVETIFDCKFK---------PDDPNVLATASFDGTIKVWDINT 384
           G  D   K WD    +G    + + +F          P   ++LA  S+D  ++++D   
Sbjct: 737 GSDDCKLKVWDL--RVGTTPVLTNSRFTMGVTSIQSCPQREHLLAVGSYDENLRLFDTRH 564

Query: 385 LTAVYTSPGNEGVIFALSWAPGDLNCIAGATSRNGAFIWDIQKG-----KIIQRFNEH 437
           +    ++   EG ++ + W P     +  AT  NG  I D  K      +++  +  H
Sbjct: 563 MRQPLSTTALEGGVWRVKWDPFXARYVLTATMHNGFHIVDSSKPEEDCLRVVSHYTNH 390

 Score = 32.7 bits (73), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 19/63 (30%), Positives = 31/63 (49%), Gaps = 10/63 (15%)
 Frame = -2

Query: 160 QKKGKVAFGHIDGSISIF------QPDE----EDPVTALEWDPLSTDYLLVANLHFGIRL 209
           Q++  +A G  D ++ +F      QP      E  V  ++WDP    Y+L A +H G  +
Sbjct: 629 QREHLLAVGSYDENLRLFDTRHMRQPLSTTALEGGVWRVKWDPFXARYVLTATMHNGFHI 450

Query: 210 LDS 212
           +DS
Sbjct: 449 VDS 441
>11915
          Length = 737

 Score = 35.0 bits (79), Expect = 0.18,   Method: Compositional matrix adjust.
 Identities = 20/65 (30%), Positives = 32/65 (49%)
 Frame = +1

Query: 319 LPPGHVVCCFLDGGVGLYDMGAKKWDFLRELGHVETIFDCKFKPDDPNVLATASFDGTIK 378
           L  GHV      G + L++    K   +  + H  T+ D  F  D+   L +AS DGT+K
Sbjct: 451 LATGHV-----SGRIKLWNCETGKL-LIEMMDHKATVHDLHFAADNSLCLMSASHDGTVK 612

Query: 379 VWDIN 383
           +W+ +
Sbjct: 613 LWEFD 627

 Score = 34.3 bits (77), Expect = 0.30,   Method: Compositional matrix adjust.
 Identities = 23/81 (28%), Positives = 34/81 (41%)
 Frame = +1

Query: 561 VSTLNGHTAPVRGLMWNTEIPYLLISGSWDYTIKVWDTRGGVCLDTVYDHGADVYGLTCH 620
           +ST N +    +    N     +L +G     IK+W+   G  L  + DH A V+ L   
Sbjct: 382 ISTNNCYKQRWKRQQQNDSSTLVLATGHVSGRIKLWNCETGKLLIEMMDHKATVHDLHFA 561

Query: 621 PSRPFTMASCSRDSTVRLWSL 641
                 + S S D TV+LW  
Sbjct: 562 ADNSLCLMSASHDGTVKLWEF 624

 Score = 30.4 bits (67), Expect = 4.8,   Method: Compositional matrix adjust.
 Identities = 15/58 (25%), Positives = 29/58 (50%)
 Frame = +1

Query: 540 ILCSGSDDGSVRIWDYTQDACVSTLNGHTAPVRGLMWNTEIPYLLISGSWDYTIKVWD 597
           +L +G   G +++W+      +  +  H A V  L +  +    L+S S D T+K+W+
Sbjct: 448 VLATGHVSGRIKLWNCETGKLLIEMMDHKATVHDLHFAADNSLCLMSASHDGTVKLWE 621
>01557
          Length = 953

 Score = 34.7 bits (78), Expect = 0.24,   Method: Compositional matrix adjust.
 Identities = 24/80 (30%), Positives = 32/80 (40%), Gaps = 4/80 (5%)
 Frame = +2

Query: 566 GHTAPVRGLMWNTEIPYLLISGSWDYTIKVWDTRGGVCLDTVYD----HGADVYGLTCHP 621
            H AP+  L      P   +S   D T+ VWD  G   L +VY     H   + GL    
Sbjct: 215 AHKAPINQLCVFKSRPQQAVSTCLDNTLNVWDLSGAD-LCSVYRARAAHTNKLTGLALSA 391

Query: 622 SRPFTMASCSRDSTVRLWSL 641
           +    + +C R    RLW L
Sbjct: 392 TTAAQLITCDRGGCARLWDL 451
>14500
          Length = 1238

 Score = 34.7 bits (78), Expect = 0.24,   Method: Compositional matrix adjust.
 Identities = 17/66 (25%), Positives = 42/66 (63%)
 Frame = +3

Query: 488 WSQNNKDMIATGCEDKNIRVFYVATSSNQPLKVFSGHTARVFHVKWSPLREGILCSGSDD 547
           WS+ ++++I++    +N  + +   + ++  ++ +GHTARV H+  SP  E ++ + +D+
Sbjct: 357 WSKEHRELISSHGFAQNQLIIWKYPAMSRVAEL-TGHTARVLHMAMSPDGETVVSAAADE 533

Query: 548 GSVRIW 553
            ++R+W
Sbjct: 534 -TLRLW 548
>37142
          Length = 327

 Score = 34.3 bits (77), Expect = 0.29,   Method: Compositional matrix adjust.
 Identities = 21/64 (32%), Positives = 32/64 (50%), Gaps = 6/64 (9%)
 Frame = +2

Query: 540 ILCSGSDDGSVRIW------DYTQDACVSTLNGHTAPVRGLMWNTEIPYLLISGSWDYTI 593
           ++  G+D+GSV ++      D   D  V  L  HT  V+ L +N     LL SG+ +  I
Sbjct: 2   VIVGGADNGSVLVYSAQKMIDGDADCSVLQLTKHTGAVKALDFNPFQTNLLASGASESEI 181

Query: 594 KVWD 597
            +WD
Sbjct: 182 YIWD 193

 Score = 33.1 bits (74), Expect = 0.81,   Method: Compositional matrix adjust.
 Identities = 17/69 (24%), Positives = 33/69 (47%), Gaps = 3/69 (4%)
 Frame = +2

Query: 521 FSGHTARVFHVKWSPLREGILCSGSDDGSVRIWDYTQDACVSTLNGHTAP---VRGLMWN 577
            + HT  V  + ++P +  +L SG+ +  + IWD  +     T    + P   V  + WN
Sbjct: 92  LTKHTGAVKALDFNPFQTNLLASGASESEIYIWDLNKPDNPMTPGQKSQPPEEVSCVAWN 271

Query: 578 TEIPYLLIS 586
            ++ ++L S
Sbjct: 272 RQVQHILAS 298
>27806
          Length = 419

 Score = 34.3 bits (77), Expect = 0.30,   Method: Compositional matrix adjust.
 Identities = 20/66 (30%), Positives = 36/66 (54%)
 Frame = -1

Query: 361 KPDDPNVLATASFDGTIKVWDINTLTAVYTSPGNEGVIFALSWAPGDLNCIAGATSRNGA 420
           +P  P ++ TAS D T +++ I T   V T  G++G + A+ + PG  + +  A+  + A
Sbjct: 398 RPGHP-IIGTASADHTARIYSIETGACVLTYGGHQGSVNAVRFHPGQ-DLVLTASGDHTA 225

Query: 421 FIWDIQ 426
            +W  Q
Sbjct: 224 HVWRAQ 207

 Score = 31.6 bits (70), Expect = 2.4,   Method: Compositional matrix adjust.
 Identities = 18/57 (31%), Positives = 29/57 (50%)
 Frame = -1

Query: 540 ILCSGSDDGSVRIWDYTQDACVSTLNGHTAPVRGLMWNTEIPYLLISGSWDYTIKVW 596
           I+ + S D + RI+     ACV T  GH   V  + ++     L+++ S D+T  VW
Sbjct: 383 IIGTASADHTARIYSIETGACVLTYGGHQGSVNAVRFHPGQD-LVLTASGDHTAHVW 216
>16199
          Length = 694

 Score = 34.3 bits (77), Expect = 0.32,   Method: Composition-based stats.
 Identities = 12/38 (31%), Positives = 22/38 (57%)
 Frame = +2

Query: 540 ILCSGSDDGSVRIWDYTQDACVSTLNGHTAPVRGLMWN 577
           I  +G++D  ++IWD  + A V+   GH  PV  + ++
Sbjct: 113 IFATGTEDSVIKIWDLKERANVANFQGHQGPVTSISFS 226
>38362
          Length = 1255

 Score = 33.9 bits (76), Expect = 0.40,   Method: Compositional matrix adjust.
 Identities = 22/63 (34%), Positives = 32/63 (50%), Gaps = 3/63 (4%)
 Frame = -1

Query: 516 QPLKVFSGHTARVFHVKWSPLREGILCSGSDDGSVRIW--DYTQD-ACVSTLNGHTAPVR 572
           + + +F  H ++V+ V W+ +   IL S   DG VRIW  +Y    AC+S L G   P  
Sbjct: 643 RQVGLFDSHDSQVWRVSWN-VTGTILVSSGADGCVRIWKANYLGSWACISVLKGDGTPGD 467

Query: 573 GLM 575
             M
Sbjct: 466 SAM 458
>07741
          Length = 2119

 Score = 33.9 bits (76), Expect = 0.48,   Method: Compositional matrix adjust.
 Identities = 25/87 (28%), Positives = 42/87 (48%), Gaps = 2/87 (2%)
 Frame = +1

Query: 525 TARVFHVKWSPLREGILCSGSDDGSVRIWD--YTQDACVSTLNGHTAPVRGLMWNTEIPY 582
           TA  FH +    ++ +   G+++G V +    YT    + TL+ H   V  + WN   P 
Sbjct: 121 TAFDFHKQ----KDYLFLVGTEEGKVHVCSKAYTSH-FIDTLDSHNMAVYKVAWNHYHPK 285

Query: 583 LLISGSWDYTIKVWDTRGGVCLDTVYD 609
           +  + S D+ +K+W+  GG   DT  D
Sbjct: 286 IYATCSADWNVKIWE-NGGKPTDTGXD 363

 Score = 30.0 bits (66), Expect = 6.4,   Method: Compositional matrix adjust.
 Identities = 28/125 (22%), Positives = 52/125 (41%), Gaps = 15/125 (12%)
 Frame = +1

Query: 441 GIFYIAWSHKDSKRIATCSGDGFCII------------RTVDGKLLHKYKHPAAVFGCDW 488
            ++ +AW+H   K  ATCS D    I             ++  K L  +    +V    W
Sbjct: 247 AVYKVAWNHYHPKIYATCSADWNVKIWENGGKPTDTGXDSLSRKPLFSFDLNNSVGDVAW 426

Query: 489 SQNNKDMIATGCEDKNIRVFYVATSSNQPL---KVFSGHTARVFHVKWSPLREGILCSGS 545
           +  +  + A    D  + V+ ++ +  +PL    V      ++ H++++P    IL  G 
Sbjct: 427 APYSSTVFAAVTADGKVCVYDLSVNKYEPLCEQMVAQKKKTKLTHIEFNP-SYPILIVGD 603

Query: 546 DDGSV 550
           D G+V
Sbjct: 604 DRGNV 618
>38039
          Length = 816

 Score = 33.9 bits (76), Expect = 0.49,   Method: Compositional matrix adjust.
 Identities = 22/78 (28%), Positives = 36/78 (46%)
 Frame = -1

Query: 52  HAIMSEHKKTITAISWCPHNPDLFASSSTDNLVIIWNVAEQKVIAKLDNIKETPACLGWC 111
           H    +H   IT ++ C     LFASSS D  + +WN  E+  + ++  +   P  +G+C
Sbjct: 528 HKPDDDHVDLITGLTSCS-RMKLFASSSMDGTIRVWN--EENRLVRVLRLNAIPNSIGFC 358

Query: 112 WNTHDAVAFVSQKGPLLI 129
                     S +G LL+
Sbjct: 357 ----------SSRGDLLV 334
>04395
          Length = 1145

 Score = 33.5 bits (75), Expect = 0.50,   Method: Compositional matrix adjust.
 Identities = 23/97 (23%), Positives = 50/97 (51%), Gaps = 3/97 (3%)
 Frame = +3

Query: 504 NIRVFYVATSSNQPLKVFSGHTAR--VFHVKWSPLREGILCSGSDDGSVRIWDYTQDAC- 560
            +++F V  +S++P ++FS       +  V   P +  I+ +GS DG++ +WD       
Sbjct: 405 QLKLFDVRQNSDEPAQIFSATDDHWSLLCVDKHPGQLHIVATGSQDGTLTVWDLRHHRFP 584

Query: 561 VSTLNGHTAPVRGLMWNTEIPYLLISGSWDYTIKVWD 597
           ++TL+ H + +  + ++ +    L + S D ++  WD
Sbjct: 585 MTTLDAHHSSMWEVRFHQQHTPHLFTCSEDGSLWHWD 695

 Score = 29.3 bits (64), Expect = 9.8,   Method: Compositional matrix adjust.
 Identities = 18/101 (17%), Positives = 46/101 (45%), Gaps = 4/101 (3%)
 Frame = +3

Query: 366 NVLATASFDGTIKVWDI----NTLTAVYTSPGNEGVIFALSWAPGDLNCIAGATSRNGAF 421
            VL   SF G +K++D+    +    ++++  +   +  +   PG L+ +A  +      
Sbjct: 378 QVLTVNSF-GQLKLFDVRQNSDEPAQIFSATDDHWSLLCVDKHPGQLHIVATGSQDGTLT 554

Query: 422 IWDIQKGKIIQRFNEHGKNGIFYIAWSHKDSKRIATCSGDG 462
           +WD++  +      +   + ++ + +  + +  + TCS DG
Sbjct: 555 VWDLRHHRFPMTTLDAHHSSMWEVRFHQQHTPHLFTCSEDG 677
>03395
          Length = 2795

 Score = 33.1 bits (74), Expect = 0.66,   Method: Compositional matrix adjust.
 Identities = 46/207 (22%), Positives = 90/207 (43%), Gaps = 14/207 (6%)
 Frame = +2

Query: 368 LATASFDGTIKVWDI--NTLTA------VYTSPGNEGVIFALSWAPGDLNCIAGATSRNG 419
           L +   +G ++VWDI  + LT       V     ++G + A+     D  C++ A++   
Sbjct: 41  LVSGGGEGQVRVWDIVKDMLTGKTRGDLVANMKEHKGKVTAIQIHTNDRCCVS-ASTDGS 217

Query: 420 AFIWDI---QKGKIIQRFNEHGKNGIFY-IAWSHKDSKRIATCSGDGFCIIRTVDGKLLH 475
             IWD+    + +I+        N +F  + +  KD   + + +          DG LL 
Sbjct: 218 TIIWDLITNTRSQIVL------ANTLFKCVCFGGKDLHILTSGTDHKIGYWEVGDGGLLR 379

Query: 476 KYK--HPAAVFGCDWSQNNKDMIATGCEDKNIRVFYVATSSNQPLKVFSGHTARVFHVKW 533
           + +     A+   D  ++ +  I TG ED  ++++    +  +      GH+ ++   + 
Sbjct: 380 ELEGSQTGAINTIDIDRDGQ-TILTGGEDSLLKLWRY--NEGEVTHTGIGHSNQITKARI 550

Query: 534 SPLREGILCSGSDDGSVRIWDYTQDAC 560
            P R  I+ SG +DG++ IW +  D C
Sbjct: 551 CPNRHYIV-SGGEDGALHIWKF-PDGC 625
>04524
          Length = 1340

 Score = 33.1 bits (74), Expect = 0.72,   Method: Compositional matrix adjust.
 Identities = 27/88 (30%), Positives = 44/88 (50%), Gaps = 2/88 (2%)
 Frame = -1

Query: 519  KVFSGHTARVFHVKWSPLREGILCSGSDDGSVRIWDYTQDACVSTLN-GHTAPVRGLMWN 577
            ++  GH + V  V  +  REG + +   D  +R+  +     + T   GHT  V  L++ 
Sbjct: 1046 QLLLGHLSMVLDVCLTG-REGHVVTCDRDEKIRVSQFPNAYNIHTYCLGHTQFVNCLVYV 870

Query: 578  TEIPYLLISGSWDYTIKVWDTRGG-VCL 604
             E   +LISGS D T++ W+  G  +CL
Sbjct: 869  EEF-RVLISGSGDCTVRAWNMEGKQLCL 789
>31054
          Length = 392

 Score = 32.7 bits (73), Expect = 0.95,   Method: Compositional matrix adjust.
 Identities = 20/75 (26%), Positives = 37/75 (49%)
 Frame = -2

Query: 534 SPLREGILCSGSDDGSVRIWDYTQDACVSTLNGHTAPVRGLMWNTEIPYLLISGSWDYTI 593
           +P +      GS D  V+ W +     +  L+GH A +  L  N++   +L+SG+ + T+
Sbjct: 388 TPSKAVHFAXGSPD-XVKQWKFPDGNFIQNLSGHNAIINTLAVNSD--GVLVSGADNGTM 218

Query: 594 KVWDTRGGVCLDTVY 608
            +WD R G     ++
Sbjct: 217 HLWDWRTGYNFQRIH 173
>03044
          Length = 1952

 Score = 32.7 bits (73), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 19/89 (21%), Positives = 36/89 (40%)
 Frame = -2

Query: 471  GKLLHKYKHPAAVFGCDWSQNNKDMIATGCEDKNIRVFYVATSSNQPLKVFSGHTARVFH 530
            G +  K+        C  +  +++ +A    D  ++++    S  Q       H  RV  
Sbjct: 1816 GNMAEKHSFGVKAVTCHAASGDRNGLALSLNDHEVKIYKKNGSKWQETDTLGEHGQRVTG 1637

Query: 531  VKWSPLREGILCSGSDDGSVRIWDYTQDA 559
            + W+P    I+  G+D  +  +W Y QD 
Sbjct: 1636 IDWAPKSNRIVTCGADRNAY-VWTY-QDG 1556
>14105
          Length = 429

 Score = 32.3 bits (72), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 14/48 (29%), Positives = 23/48 (47%)
 Frame = +3

Query: 516 QPLKVFSGHTARVFHVKWSPLREGILCSGSDDGSVRIWDYTQDACVST 563
           +PL  F  ++  V  V WSP+   +  +    G + +W+  QD  V T
Sbjct: 24  KPLYSFEDNSDYVMDVAWSPVHPALFAAVDGSGRLDLWNLNQDTEVPT 167
>04088
          Length = 511

 Score = 32.3 bits (72), Expect = 1.3,   Method: Composition-based stats.
 Identities = 23/79 (29%), Positives = 37/79 (46%), Gaps = 2/79 (2%)
 Frame = +3

Query: 501 EDKNIRVFYVATSSNQPLKVFSGHTARVFHVKWSPLREGILC-SGSDDGSVRIWDYTQDA 559
           +D  +R+  +   + + L  F+GH    + +      E  L  SGS+DG V  WD  +  
Sbjct: 90  QDNTVRL--MDKDTGEMLNEFTGHKHSQYKIDSCLNNEDTLVVSGSEDGKVYFWDLVEAK 263

Query: 560 CVSTLNGHTA-PVRGLMWN 577
            V TL+  T  PV  L ++
Sbjct: 264 LVDTLDHKTTRPVHSLSFH 320
>12140
          Length = 727

 Score = 31.2 bits (69), Expect = 2.7,   Method: Compositional matrix adjust.
 Identities = 41/143 (28%), Positives = 58/143 (40%), Gaps = 23/143 (16%)
 Frame = +2

Query: 521 FSGHTARVFHVKWSPLREG-ILCSGSDDGSVRIWDYTQDACVSTL---NGHTAPVRGLMW 576
           +S H + V  V ++P   G IL  GS DGS+ I   T D    +    N HT     + W
Sbjct: 26  YSNHDSSVNSVCFAPHELGLILACGSSDGSLSIISTTGDGNWDSKKINNAHTIGCNAVSW 205

Query: 577 N-TEIPYLL-------------ISGSWDYTIKVW--DTRGGVCLDTVYDHGADVYGLTCH 620
             +  P  L             +SG  D  +K+W  D  G V    +  H   V  +   
Sbjct: 206 APSTAPNALFDQSARQQPVKRFVSGGCDNLVKIWREDETGWVEDQKLEGHSDWVRDVAWA 385

Query: 621 PSRPF---TMASCSRDSTVRLWS 640
           PS       +ASCS+D  V +W+
Sbjct: 386 PSIGLPRNVIASCSQDCRVIIWT 454
>01462
          Length = 995

 Score = 28.9 bits (63), Expect(2) = 2.9,   Method: Compositional matrix adjust.
 Identities = 18/57 (31%), Positives = 31/57 (54%)
 Frame = +2

Query: 330 DGGVGLYDMGAKKWDFLRELGHVETIFDCKFKPDDPNVLATASFDGTIKVWDINTLT 386
           D  + ++D+ A ++    E GH + I     K +D     +AS DGT+++WDI + T
Sbjct: 260 DRKIHVWDIEAGQYLNAME-GHKDYIHKVVMK-NDAQECVSASEDGTVRMWDIRSST 424

 Score = 20.8 bits (42), Expect(2) = 2.9,   Method: Compositional matrix adjust.
 Identities = 7/28 (25%), Positives = 14/28 (50%)
 Frame = +3

Query: 402 SWAPGDLNCIAGATSRNGAFIWDIQKGK 429
           +W+P  ++C       NG  +W + + K
Sbjct: 438 AWSPAKMSCAVDRCWGNGYAVWHLTQRK 521
>31384
          Length = 474

 Score = 30.8 bits (68), Expect = 3.6,   Method: Compositional matrix adjust.
 Identities = 20/77 (25%), Positives = 32/77 (41%)
 Frame = -1

Query: 495 MIATGCEDKNIRVFYVATSSNQPLKVFSGHTARVFHVKWSPLREGILCSGSDDGSVRIWD 554
            + +G  D  +  + V  S     K    HT  V  V WS     +  + S D + ++WD
Sbjct: 225 FLISGSWDNKVSCWEVQQSGQTIPKAQQTHTGPVLDVDWSDDGTKVF-TASCDKTAKVWD 49

Query: 555 YTQDACVSTLNGHTAPV 571
              + C+  +  H APV
Sbjct: 48  LNSNQCMQ-IAQHDAPV 1
>32214
          Length = 335

 Score = 30.8 bits (68), Expect = 3.7,   Method: Composition-based stats.
 Identities = 20/51 (39%), Positives = 29/51 (56%), Gaps = 2/51 (3%)
 Frame = -3

Query: 330 DGGVGLYDMGAKKWDFLRELGHVETIFD--CKFKPDDPNVLATASFDGTIK 378
           D G G+ ++  K+W ++ E G V   FD  C+ + D  NV  T+ FDG IK
Sbjct: 282 DIGEGIREVVVKEW-YVAE-GDVVHQFDPICEVQSDKANVTITSRFDGVIK 136
>30295
          Length = 593

 Score = 30.4 bits (67), Expect = 4.3,   Method: Compositional matrix adjust.
 Identities = 29/117 (24%), Positives = 46/117 (39%), Gaps = 1/117 (0%)
 Frame = +2

Query: 351 HVETIFDCKFKPDDPNVLATASFDGTIKVWDINTLTAVYTSPGNEGVIFALSWAP-GDLN 409
           H+  I+   +  D  N L +AS DG + VWD  T   V+  P     +   ++AP G   
Sbjct: 242 HLAKIYAMHWATDSRN-LVSASQDGKLIVWDGYTTNKVHAIPLRSSWVMTCAYAPSGGYV 418

Query: 410 CIAGATSRNGAFIWDIQKGKIIQRFNEHGKNGIFYIAWSHKDSKRIATCSGDGFCII 466
              G  +    +    ++G +       G  G +       D  +I T SGD  C +
Sbjct: 419 ACGGLDNICSIYSLKTREGNVRVSRELPGHTG-YLSCCRFIDDNQIVTSSGDMTCAL 586
>02090
          Length = 1841

 Score = 30.4 bits (67), Expect = 4.4,   Method: Compositional matrix adjust.
 Identities = 23/86 (26%), Positives = 39/86 (45%), Gaps = 1/86 (1%)
 Frame = -3

Query: 538  EGILC-SGSDDGSVRIWDYTQDACVSTLNGHTAPVRGLMWNTEIPYLLISGSWDYTIKVW 596
            +G +C S   DG++ +WD      V    GHT     +  + +   L  +G  D T++ W
Sbjct: 1593 DGKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISPDGTKLW-TGGLDNTVRSW 1417

Query: 597  DTRGGVCLDTVYDHGADVYGLTCHPS 622
            D R G  L   +D  + ++ L   P+
Sbjct: 1416 DLREGRQLQQ-HDFSSQIFSLGYCPT 1342
>30428
          Length = 385

 Score = 30.4 bits (67), Expect = 4.4,   Method: Composition-based stats.
 Identities = 19/58 (32%), Positives = 27/58 (46%)
 Frame = -3

Query: 251 GVLRIWNVSRTTPIDNFKLKKTGFHCFHVVNSPPKKKFSVQSPNKNHYISSTSEAVPP 308
           G +++ NV R    + F+L  T   CFH +       F V SPN N  + S+    PP
Sbjct: 194 GRIKLGNVDRFLNKNLFRL--TLNICFHFIPFSVLFSFQVISPNHNRRVKSSKNYFPP 27
>14555
          Length = 627

 Score = 30.0 bits (66), Expect = 5.9,   Method: Compositional matrix adjust.
 Identities = 17/52 (32%), Positives = 29/52 (55%)
 Frame = -3

Query: 545 SDDGSVRIWDYTQDACVSTLNGHTAPVRGLMWNTEIPYLLISGSWDYTIKVW 596
           ++D +V +WD  +    + L GH   V  L  + +    L +GSWDYT+++W
Sbjct: 409 TNDYTVNVWDALKGMRSTILYGHDNRVSCLRISPD-GTSLCTGSWDYTLRIW 257
>05642
          Length = 445

 Score = 30.0 bits (66), Expect = 6.5,   Method: Compositional matrix adjust.
 Identities = 20/59 (33%), Positives = 28/59 (47%), Gaps = 2/59 (3%)
 Frame = -1

Query: 521 FSGHTARVFHVKWSPLREGILC-SGSDDGSVRIWDYTQDACVSTLNGHTA-PVRGLMWN 577
           F+GH    + +      E  L  SGS+DG V  WD  +   V TL+  T  PV  L ++
Sbjct: 427 FTGHKHSQYKIDSCLNNEDTLVVSGSEDGKVYFWDLVEAKLVDTLDHKTTRPVHSLSFH 251
>30297
          Length = 822

 Score = 30.0 bits (66), Expect = 6.9,   Method: Compositional matrix adjust.
 Identities = 11/18 (61%), Positives = 16/18 (88%)
 Frame = -3

Query: 365 PNVLATASFDGTIKVWDI 382
           PN+LATAS+DG + VW++
Sbjct: 667 PNLLATASYDGEVIVWNM 614
>06338
          Length = 1199

 Score = 29.6 bits (65), Expect = 8.7,   Method: Composition-based stats.
 Identities = 22/73 (30%), Positives = 32/73 (43%)
 Frame = -2

Query: 1016 EEINDLHKKCNLPPAEECTQLAETARADGNVFETIKYYLLSQEPEKALPIGIDFVKGCIS 1075
            E IN     CN       +QLA   RA+   F+TIKY  L ++  K        +   I 
Sbjct: 325  E*INPHITGCNAGKEN*SSQLASITRANSACFQTIKYNCLVKK*NKEQ*KKFHIILSQIK 146

Query: 1076 NSNWTLDTVYPVL 1088
            + N TL+T+   +
Sbjct: 145  SRNCTLNTILSTM 107
>20271
          Length = 567

 Score = 29.3 bits (64), Expect = 9.4,   Method: Compositional matrix adjust.
 Identities = 13/36 (36%), Positives = 20/36 (55%)
 Frame = -1

Query: 370 TASFDGTIKVWDINTLTAVYTSPGNEGVIFALSWAP 405
           TASFD T+K+W+I     V +   N   +  + W+P
Sbjct: 216 TASFDWTVKLWNIKEQKYVCSFEDNSDYVSDVQWSP 109
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31982044|ref|NP_758494.2| neurotrimin [Mus musculus]
         (344 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

13135                                                                  82   3e-16
27666                                                                  65   5e-11
18345                                                                  55   5e-08
20110                                                                  52   3e-07
08294                                                                  47   1e-05
37675                                                                  40   0.001
29990                                                                  38   0.005
25766                                                                  29   0.007
17678                                                                  38   0.008
35419                                                                  37   0.009
25455                                                                  36   0.017
36498                                                                  36   0.024
32888                                                                  31   0.027
34811                                                                  35   0.036
32174                                                                  35   0.040
29932                                                                  35   0.041
17530                                                                  35   0.046
36700                                                                  35   0.047
06028                                                                  33   0.11 
38127                                                                  33   0.14 
11855                                                                  33   0.19 
12764                                                                  32   0.27 
11732                                                                  30   2.0  
29881                                                                  29   2.3  
19453                                                                  28   3.8  
16597                                                                  28   4.1  
20244                                                                  28   7.1  
>13135
          Length = 849

 Score = 82.4 bits (202), Expect = 3e-16,   Method: Compositional matrix adjust.
 Identities = 52/139 (37%), Positives = 78/139 (56%), Gaps = 6/139 (4%)
 Frame = -1

Query: 96  TQYSIEIQNVDVYDEGPYTCSVQTDNHPKTSRVH-LIVQVSPKI--VEISSDISINEGNN 152
           T + + IQN  V DEG YTC VQ  N       H L++   P+I  ++ SSD+S +EG +
Sbjct: 507 TSWRLRIQNGQVTDEGVYTCQVQLSNQNYAKAFHQLVIIQMPQISDLDTSSDVSKSEGQS 328

Query: 153 ISLTCIATGRPEPTVTWRHISPKAV---GFVSEDEYLEIQGITREQSGEYECSASNDVAA 209
           + L C A+GRP P+V W  ++ + +   G    +  L I  +  E +G Y+CS+SN  A 
Sbjct: 327 LVLRCHASGRPTPSVKWTRMAGELLPSGGREHLESDLVIPQLKPEHAGIYKCSSSNS-AG 151

Query: 210 PVVRRVKVTVNYPPYISEA 228
              R ++VTVN+ P +S A
Sbjct: 150 SDFRNIRVTVNFAPVLSSA 94
>27666
          Length = 873

 Score = 64.7 bits (156), Expect = 5e-11,   Method: Compositional matrix adjust.
 Identities = 55/201 (27%), Positives = 90/201 (44%), Gaps = 27/201 (13%)
 Frame = +1

Query: 50  GESATLRCTIDNRVTR-VAWLNRSTILYAGNDKWCLDPRVVLLSNT-------------- 94
           G +A + CT+ N+ T  V W+++ T      +   +D  V L  N               
Sbjct: 205 GGTARINCTVANKQTNNVFWIHQDT-----GELISMDKAVTLQINQMIGGLRKFEIVQHG 369

Query: 95  ---QTQYSIEIQNVDVYDEGPYTCSVQTDNHPKTSRVH----LIVQVSPKIV--EISSDI 145
              +  +++ I+ +   D G Y C V+  N    S+V     L VQV PKI   E ++ +
Sbjct: 370 PPDRLTFTLVIRRLRQQDAGTYVCQVKIQNENILSQVQKIGTLTVQVPPKIRPGETTTLV 549

Query: 146 SINEGNNISLTCIATGRPEPTVTWRHISPKAV--GFVS-EDEYLEIQGITREQSGEYECS 202
            I++  N SL C +TG P P +TW  +  +A+  G+       L + G T +  G Y C 
Sbjct: 550 EIDQNQNSSLVCSSTGIPAPNITWTRLDGRALPTGYSQFRGRELPLNGATVDHMGVYRCV 729

Query: 203 ASNDVAAPVVRRVKVTVNYPP 223
           A+N++  P     +V V + P
Sbjct: 730 ANNNIKPPDDHLCEVRVFHAP 792
>18345
          Length = 461

 Score = 55.1 bits (131), Expect = 5e-08,   Method: Compositional matrix adjust.
 Identities = 39/133 (29%), Positives = 61/133 (45%), Gaps = 6/133 (4%)
 Frame = +1

Query: 99  SIEIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVSPKIVEISSD-ISINEGNNISLTC 157
           ++ I++V + D G Y C + T          ++      + E S D +S+ EG+  +L C
Sbjct: 1   NLLIRHVRLNDTGVYECRINTQPSQIKQVTLVVQVPPVVLSEGSPDRVSLKEGDTATLVC 180

Query: 158 IATGRPEPTVTW-----RHISPKAVGFVSEDEYLEIQGITREQSGEYECSASNDVAAPVV 212
             TG P P VTW     R +  +     S    L +  +TR     YEC A N V   V 
Sbjct: 181 NVTGVPSPDVTWYKRNTRQLDAQKERVGSTGPVLVMYNVTRHCDDIYECYADNGVPPAVT 360

Query: 213 RRVKVTVNYPPYI 225
           + ++VTV+Y P +
Sbjct: 361 KAIRVTVDYAPEV 399

 Score = 38.5 bits (88), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 20/64 (31%), Positives = 29/64 (45%)
 Frame = +1

Query: 236 GQKGTLQCEASAVPSAEFQWFKDDKRLVEGKKGVKVENRPFLSKLTFFNVSEHDYGNYTC 295
           G   TL C  + VPS +  W+K + R ++ +K       P    L  +NV+ H    Y C
Sbjct: 157 GDTATLVCNVTGVPSPDVTWYKRNTRQLDAQKERVGSTGPV---LVMYNVTRHCDDIYEC 327

Query: 296 VASN 299
            A N
Sbjct: 328 YADN 339
>20110
          Length = 820

 Score = 52.0 bits (123), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 41/147 (27%), Positives = 66/147 (44%), Gaps = 13/147 (8%)
 Frame = -1

Query: 91  LSNTQTQYSIEIQNVDVYDEGPYTCSVQT-----DNHPKTSRVHLIVQVSPKIV--EISS 143
           LS  +  Y + ++ +   D G YTC+V+      +  P T   +L VQV P I   + ++
Sbjct: 700 LSGDRETYMLVVRRLVETDAGIYTCTVRITAVSYEEWP-TKIGNLTVQVPPSIKPGDTTA 524

Query: 144 DISINEGNNISLTCIATGRPEPTVTWRHISPKAVGFVS------EDEYLEIQGITREQSG 197
            + I +G N +L C A+G P P +TW        GF+           L +  +T    G
Sbjct: 523 VLQIEQGQNSTLVCAASGIPAPNITWTR---SDGGFLPIGVAQFRSATLPMNNVTVRDMG 353

Query: 198 EYECSASNDVAAPVVRRVKVTVNYPPY 224
            Y C A N++  P     +V V + P+
Sbjct: 352 VYRCVADNNIKPPAEHLAEVLVFHAPF 272

 Score = 30.0 bits (66), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 11/16 (68%), Positives = 12/16 (75%)
 Frame = -3

Query: 154 SLTCIATGRPEPTVTW 169
           +L CI  G PEPTVTW
Sbjct: 218 NLECIVKGHPEPTVTW 171
>08294
          Length = 1849

 Score = 47.0 bits (110), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 31/108 (28%), Positives = 56/108 (51%), Gaps = 9/108 (8%)
 Frame = +2

Query: 113 YTCSVQTDNHPKTSRVHLIVQVS----PKIVEISSDISINEGNNISLTCIATGRPEPTVT 168
           YTC      HP+   ++  + +S    P I   S++I++ EG++  L C+A G P P + 
Sbjct: 5   YTC---VATHPRQGVINATIHISIVEWPAITVKSNNITVFEGHSAILHCVAKGSPSPDIA 175

Query: 169 W----RHISPKAVGF-VSEDEYLEIQGITREQSGEYECSASNDVAAPV 211
           W    + I P A  + + ++  ++I+ +  E +G Y C A N+ A P+
Sbjct: 176 WYRDSQPILPNARRYTLFKNGTMKIRQVFMEDNGMYACVA-NNTAGPL 316

 Score = 37.0 bits (84), Expect = 0.011,   Method: Compositional matrix adjust.
 Identities = 24/107 (22%), Positives = 45/107 (42%), Gaps = 2/107 (1%)
 Frame = +2

Query: 198 EYECSASNDVAAPVVRRVKVT-VNYPPYISEAKGTGVPVGQKGTLQCEASAVPSAEFQWF 256
           +Y C A++     +   + ++ V +P    ++    V  G    L C A   PS +  W+
Sbjct: 2   DYTCVATHPRQGVINATIHISIVEWPAITVKSNNITVFEGHSAILHCVAKGSPSPDIAWY 181

Query: 257 KDDKRLV-EGKKGVKVENRPFLSKLTFFNVSEHDYGNYTCVASNKLG 302
           +D + ++   ++    +N     +  F      D G Y CVA+N  G
Sbjct: 182 RDSQPILPNARRYTLFKNGTMKIRQVFM----EDNGMYACVANNTAG 310
>37675
          Length = 741

 Score = 40.4 bits (93), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 29/98 (29%), Positives = 46/98 (46%), Gaps = 7/98 (7%)
 Frame = +2

Query: 113 YTCSVQTDNHPKTSRVHLIVQVSPKIVEISSDISINEGN-NISLTCIATGRPEPTVTWRH 171
           Y+C   TD  P + +VH +    P +V++S    I     N  + C A G P+PT++W  
Sbjct: 5   YSCEDSTD--PSSLQVHALKVQMPPVVKVSPHSLIYPARLNAKMKCHAEGVPKPTISWLF 178

Query: 172 ----IS--PKAVGFVSEDEYLEIQGITREQSGEYECSA 203
               IS  P+     S +E L +     + +G Y+C A
Sbjct: 179 NNVPISEDPQHYDLESANELLVVYNAGDQDTGAYKCVA 292
>29990
          Length = 434

 Score = 38.1 bits (87), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 29/112 (25%), Positives = 48/112 (42%), Gaps = 5/112 (4%)
 Frame = +3

Query: 63  VTRVAWL-NRSTILYAGNDKWCLDPRVVLLSNTQTQYSIEIQNVDVYDEGPYTC---SVQ 118
           V  + W+ N + +  +G      D R  LL +     ++ I++    D G Y C   +V 
Sbjct: 15  VPEIVWMHNNNRVEISG------DSRFSLLHDG----TLMIEDAQDDDRGVYECIARNVA 164

Query: 119 TDNHPKTSRVHLIVQ-VSPKIVEISSDISINEGNNISLTCIATGRPEPTVTW 169
            + H     +    + V+P   +   DI   EG  + L C A+G P PT +W
Sbjct: 165 GETHSNQVELRYFGERVAPXFTQRPQDIVTVEGQTVQLVCQASGHPRPTFSW 320

 Score = 35.8 bits (81), Expect = 0.024,   Method: Compositional matrix adjust.
 Identities = 30/114 (26%), Positives = 45/114 (39%), Gaps = 12/114 (10%)
 Frame = +3

Query: 161 GRPEPTVTWRH------ISPKAVGFVSEDEYLEIQGITREQSGEYECSASNDVAAPVVRR 214
           G+P P + W H      IS  +   +  D  L I+    +  G YEC A N   A     
Sbjct: 6   GKPVPEIVWMHNNNRVEISGDSRFSLLHDGTLMIEDAQDDDRGVYECIARN--VAGETHS 179

Query: 215 VKVTVNY------PPYISEAKGTGVPVGQKGTLQCEASAVPSAEFQWFKDDKRL 262
            +V + Y      P +    +      GQ   L C+AS  P   F W ++ ++L
Sbjct: 180 NQVELRYFGERVAPXFTQRPQDIVTVEGQTVQLVCQASGHPRPTFSWTRNLEQL 341
>25766
          Length = 469

 Score = 29.3 bits (64), Expect(2) = 0.007,   Method: Compositional matrix adjust.
 Identities = 23/91 (25%), Positives = 38/91 (41%), Gaps = 2/91 (2%)
 Frame = +1

Query: 169 WRHISPKAVGFVSE-DEYLEIQGITREQSGEYECSASNDVAAPVVRRVKVTVNYPPYIS- 226
           WR    +A G V E D  L+I  +T   +G Y C  ++           + ++ PP +S 
Sbjct: 25  WR----RAAGRVREYDGILQIPRVTAADAGRYRCVITSSEGITSEGFATLRISSPPVVSV 192

Query: 227 EAKGTGVPVGQKGTLQCEASAVPSAEFQWFK 257
           + +     VG      C+ S  P  + +W K
Sbjct: 193 KQRNENRQVGSSVKFHCDVSGDPVPQVRWEK 285

 Score = 27.3 bits (59), Expect(2) = 0.007,   Method: Compositional matrix adjust.
 Identities = 10/23 (43%), Positives = 15/23 (65%)
 Frame = +3

Query: 280 LTFFNVSEHDYGNYTCVASNKLG 302
           LT +N+ + D G Y C AS++ G
Sbjct: 330 LTLYNIQKEDEGRYICTASSENG 398
>17678
          Length = 876

 Score = 37.7 bits (86), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 17/35 (48%), Positives = 22/35 (62%)
 Frame = -3

Query: 280 LTFFNVSEHDYGNYTCVASNKLGHTNASIMLFGPG 314
           L    VSE D+G+YTC ASN LG  + ++ LF  G
Sbjct: 856 LIIMRVSELDFGSYTCEASNLLGKDSETMTLFDYG 752
>35419
          Length = 623

 Score = 37.4 bits (85), Expect = 0.009,   Method: Compositional matrix adjust.
 Identities = 33/118 (27%), Positives = 48/118 (40%), Gaps = 9/118 (7%)
 Frame = -2

Query: 211 VVRRVKVTVNYPPYISEAKGTGVPVGQKGTLQCEASAVPSA----EFQWFKDDKRL--VE 264
           +VRR K  +   P   E     V  G      C  +  P      + +W KD+K +  VE
Sbjct: 589 LVRR-KTQIEQAPMDLE-----VNAGTDAKFTCSGTTDPEEVHMLKIKWMKDNKEISTVE 428

Query: 265 GKKGVKVENRPFLSKLTFFNVSEHDYGNYTCVASNKLGHTNASIMLF---GPGAVSEV 319
            +    +++    + LT       D G YTC+++N L    AS ML     P   SEV
Sbjct: 427 QRMTTNIQD----NSLTISGTIVRDSGTYTCISTNGLDSAEASAMLTVKDRPDVASEV 266
>25455
          Length = 444

 Score = 36.2 bits (82), Expect = 0.017,   Method: Compositional matrix adjust.
 Identities = 25/104 (24%), Positives = 49/104 (47%), Gaps = 5/104 (4%)
 Frame = +1

Query: 212 VRRVKVTV-NYPPYISEAKGTGVPVGQKGTLQCEASAVPSAEFQWFKDDKRLVE-GKKGV 269
           +R ++V V + P ++   + T V VG+   + C A+A+P     WF + + + +  +  V
Sbjct: 46  LREMRVVVQSAPSWVVAPQVTEVEVGETAEITCNATAIPDPVTNWFVNGREISDVVEHDV 225

Query: 270 KVENRPF---LSKLTFFNVSEHDYGNYTCVASNKLGHTNASIML 310
           + ++  F     +L   NV+        C  +N+ GH  A + L
Sbjct: 226 RFQSGRFDLTSDRLILRNVTIEGRMVVQCNVTNRYGHLWADVSL 357
>36498
          Length = 478

 Score = 35.8 bits (81), Expect = 0.024,   Method: Compositional matrix adjust.
 Identities = 18/50 (36%), Positives = 28/50 (56%), Gaps = 1/50 (2%)
 Frame = +1

Query: 130 LIVQVSPKI-VEISSDISINEGNNISLTCIATGRPEPTVTWRHISPKAVG 178
           L++Q  P + V   + I+   G+ + + C+A G P PTV WR I   A+G
Sbjct: 34  LVIQGPPTVTVTPGTRITALVGDRVDIECVAEGDPTPTVFWRRIEGSALG 183

 Score = 33.9 bits (76), Expect = 0.11,   Method: Compositional matrix adjust.
 Identities = 17/39 (43%), Positives = 21/39 (53%)
 Frame = +3

Query: 272 ENRPFLSKLTFFNVSEHDYGNYTCVASNKLGHTNASIML 310
           E  P  + L F  VSE D G Y CVA N+ G T  ++ L
Sbjct: 207 EPAPGTAGLRFDPVSEGDAGRYVCVARNERGITEENVDL 323

 Score = 28.1 bits (61), Expect = 4.9,   Method: Compositional matrix adjust.
 Identities = 17/67 (25%), Positives = 30/67 (44%), Gaps = 4/67 (5%)
 Frame = +3

Query: 109 DEGPYTCSVQTDNHPKTSRVHLIVQ---VSPKI-VEISSDISINEGNNISLTCIATGRPE 164
           D G Y C  + +       V L V    V+P++ ++      + +G ++ L+C A G   
Sbjct: 258 DAGRYVCVARNERGITEENVDLTVTRTGVAPQVNIDGPGRQMLVDGQSVELSCSARGLRN 437

Query: 165 PTVTWRH 171
           P + WR 
Sbjct: 438 PLIRWRR 458
>32888
          Length = 418

 Score = 28.9 bits (63), Expect(2) = 0.027,   Method: Compositional matrix adjust.
 Identities = 12/32 (37%), Positives = 18/32 (56%)
 Frame = -2

Query: 279 KLTFFNVSEHDYGNYTCVASNKLGHTNASIML 310
           KLT  ++   D GNYTC+ SN  G  + +  +
Sbjct: 117 KLTIKSLGAEDKGNYTCIVSNTEGQIDWTFYV 22

 Score = 25.8 bits (55), Expect(2) = 0.027,   Method: Compositional matrix adjust.
 Identities = 11/38 (28%), Positives = 19/38 (50%)
 Frame = -3

Query: 236 GQKGTLQCEASAVPSAEFQWFKDDKRLVEGKKGVKVEN 273
           GQ   L C A   PS +  W+K+   +  G   V++++
Sbjct: 233 GQTVRLDCRAKGKPSPKVTWYKNGHIITNGDDRVEIKS 120

 Score = 30.8 bits (68), Expect = 0.83,   Method: Compositional matrix adjust.
 Identities = 11/22 (50%), Positives = 14/22 (63%)
 Frame = -3

Query: 148 NEGNNISLTCIATGRPEPTVTW 169
           +EG  + L C A G+P P VTW
Sbjct: 239 DEGQTVRLDCRAKGKPSPKVTW 174
>34811
          Length = 613

 Score = 35.4 bits (80), Expect = 0.036,   Method: Compositional matrix adjust.
 Identities = 27/90 (30%), Positives = 38/90 (42%), Gaps = 12/90 (13%)
 Frame = +1

Query: 181 SEDEYLEIQGITREQSGEYECSASNDVAAPVVRRVK---------VTVNYPP-YISEAKG 230
           S  E L    I R  +G Y C AS+ +  P V   +         + V Y P   S  K 
Sbjct: 58  SNSEVLSFPQIRRADAGNYSCKASSLLKVPGVGSTETVFGQGFTTINVQYAPGAASIDKI 237

Query: 231 TGVPVGQKGTLQCEAS--AVPSAEFQWFKD 258
             + VGQ+  L C A+    P A F+W ++
Sbjct: 238 DNIDVGQRLQLTCSAAPQGFPEARFKWHRN 327

 Score = 29.6 bits (65), Expect = 1.9,   Method: Compositional matrix adjust.
 Identities = 14/38 (36%), Positives = 24/38 (63%), Gaps = 3/38 (7%)
 Frame = +3

Query: 135 SPKIVE-ISSDIS--INEGNNISLTCIATGRPEPTVTW 169
           SPK++E +  +I+  I+    ++LTC   GRP+P + W
Sbjct: 468 SPKMLEQLPEEITRTISNTQPLTLTCRGQGRPQPIIEW 581
>32174
          Length = 293

 Score = 35.0 bits (79), Expect = 0.040,   Method: Composition-based stats.
 Identities = 15/49 (30%), Positives = 25/49 (51%)
 Frame = +2

Query: 21 AALCLFQGVPVRSGDATFPKAMDNVTVRQGESATLRCTIDNRVTRVAWL 69
          A  C    +   SG   F +   N +V +G++  L+C I +RV R+ W+
Sbjct: 44 AFFCFVLMITAVSGQQRFQERPQNTSVIEGQTVVLKCVILDRVGRIQWV 190
>29932
          Length = 748

 Score = 35.0 bits (79), Expect = 0.041,   Method: Compositional matrix adjust.
 Identities = 29/109 (26%), Positives = 48/109 (44%), Gaps = 3/109 (2%)
 Frame = +3

Query: 197 GEYECSASNDVAAPVVRRVKVTVNYP-PYISEAKGTGVPVGQKGTLQ--CEASAVPSAEF 253
           G+Y C+A +   + V   V+  V  P P I+      + V     ++  C+ +       
Sbjct: 12  GQYRCNAIDPRGSIVTFVVRELVLLPLPQITFRPNIPLEVEADRNIEIYCDVTNARPENV 191

Query: 254 QWFKDDKRLVEGKKGVKVENRPFLSKLTFFNVSEHDYGNYTCVASNKLG 302
           QW  D+ R + G   V ++ +     L F  ++  D G Y+C ASNK G
Sbjct: 192 QWATDNNRPLPG--SVHIDGQ----ILRFVAITPADAGGYSCTASNKYG 320
>17530
          Length = 503

 Score = 35.0 bits (79), Expect = 0.046,   Method: Compositional matrix adjust.
 Identities = 38/161 (23%), Positives = 66/161 (40%), Gaps = 21/161 (13%)
 Frame = +2

Query: 125 TSRVHLIVQVSPKIVEISSDIS---INEGNNISLTCIATG-RPEPTVTWRHISPKAVGFV 180
           ++  +L V + P    I+SDI+     EG  +  TC ++G  P PT+TW     + +  V
Sbjct: 23  SASANLTVLLPPGPPSITSDITGDVFEEGQRVRFTCSSSGGNPPPTITWTKNGVQLINGV 202

Query: 181 SE---DEYLEIQGITR----------EQSGEYECSASN--DVAAPVVRRVKVTVNYPPYI 225
            +    +     G TR          +    Y C   N  ++ + +   V + V Y P I
Sbjct: 203 QQIGVGQTSTSGGSTRNTVSVVMDHSDHQANYTCFVYNQVNINSSLTASVVLNVRYSPII 382

Query: 226 SEAKGTG--VPVGQKGTLQCEASAVPSAEFQWFKDDKRLVE 264
           +    +   V + +   + C+  A P  +F+    DKR  E
Sbjct: 383 TFEPFSPYIVRLDRPANITCQVDANPPCQFRHL--DKRCTE 499
>36700
          Length = 595

 Score = 35.0 bits (79), Expect = 0.047,   Method: Compositional matrix adjust.
 Identities = 33/135 (24%), Positives = 56/135 (41%), Gaps = 13/135 (9%)
 Frame = +1

Query: 58  TIDNRVTRVAWLNRSTILYAGNDKWCLDPRVVLLSNTQTQYSIEIQNVDVYDEGPYTCSV 117
           T +N+V  + W   ST      D+     R  +  N +    + I NVD  DE  YTC  
Sbjct: 49  TPNNQVPAITWWETST------DQISTGGRFSIEDNGRV---LVIDNVDEQDEKTYTCKG 201

Query: 118 QTDNHPKTSRVHLIVQVSPKIVEISSDISINEGNNISLTCI---ATGR--PEPTVTWRH- 171
           +      +  +HL V   P  ++    +++ +G +    C+   A+G   P P   +R+ 
Sbjct: 202 ENPAGSHSGNLHLNVTSPPIFMQHLQSLTVPQGKDAYFNCVTRSASGEKPPNPPTWYRNG 381

Query: 172 -------ISPKAVGF 179
                  +SP+ V F
Sbjct: 382 LRLDNTPLSPRQVPF 426
>06028
          Length = 1358

 Score = 33.5 bits (75), Expect = 0.11,   Method: Compositional matrix adjust.
 Identities = 38/144 (26%), Positives = 59/144 (40%), Gaps = 21/144 (14%)
 Frame = +1

Query: 186 LEIQGITREQSGEYECSASNDVAAPVVR-------RVKVTV-----------NYPPYISE 227
           L I     + SG Y C ASN+ A   +        R + T+           N P +++ 
Sbjct: 85  LIIHNPVEKDSGVYFCVASNEGAQNKISHQVDFKGRERFTLEKTAGFFHRDPNKPHFLNP 264

Query: 228 AKGTGVPVGQKGTLQCEASAVPSA---EFQWFKDDKRLVEGKKGVKVENRPFLSKLTFFN 284
                V  G  GT+   A  + S+   E +W ++ +R V+G   V+  N   +  L   N
Sbjct: 265 LGNQTVCHG--GTVAISAEFMQSSTPIEVKWLRN-RRPVDGP-SVQTFNERGIYTLAIMN 432

Query: 285 VSEHDYGNYTCVASNKLGHTNASI 308
             E   G YTC+ASN  G   + +
Sbjct: 433 AGEEHEGTYTCLASNAFGRIESHV 504

 Score = 31.6 bits (70), Expect = 0.44,   Method: Compositional matrix adjust.
 Identities = 18/47 (38%), Positives = 24/47 (51%)
 Frame = +1

Query: 254 QWFKDDKRLVEGKKGVKVENRPFLSKLTFFNVSEHDYGNYTCVASNK 300
           QW K  + +   +K  +V+     SKL   N  E D G Y CVASN+
Sbjct: 7   QWMKGTEPISNDEKYQQVDQADGYSKLIIHNPVEKDSGVYFCVASNE 147
>38127
          Length = 860

 Score = 33.5 bits (75), Expect = 0.14,   Method: Compositional matrix adjust.
 Identities = 31/128 (24%), Positives = 50/128 (39%), Gaps = 15/128 (11%)
 Frame = -1

Query: 186 LEIQGITREQSGEYECSASNDVAAPVVRRVKVTVNY---PPYISEAKGTGVPVGQKGTLQ 242
           LEIQ   R  +G Y C A  + A  V   + V V +   P  +   K   +   +   ++
Sbjct: 797 LEIQHPRRNFAGMYTCVAEYEEAG-VKSSISVDVPFYAHPKVLPFDKSKNLVQDESLVIE 621

Query: 243 CEASAVPSAEFQWFKDDKRLVEGK------------KGVKVENRPFLSKLTFFNVSEHDY 290
           C+    P     W+ D+  +V+G              G  +E     +KL    V   D 
Sbjct: 620 CKVLGYPKPVVSWYMDNVEIVDGADSRYSLKPANSYDGASIEG----AKLVIEEVQFDDA 453

Query: 291 GNYTCVAS 298
           G YTC+++
Sbjct: 452 GEYTCMSN 429

 Score = 29.6 bits (65), Expect = 1.7,   Method: Compositional matrix adjust.
 Identities = 26/124 (20%), Positives = 51/124 (41%), Gaps = 18/124 (14%)
 Frame = -1

Query: 99  SIEIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIV--QVSPKIVEISSDISINEGNNISLT 156
           ++EIQ+      G YTC  + +     S + + V     PK++      ++ +  ++ + 
Sbjct: 800 TLEIQHPRRNFAGMYTCVAEYEEAGVKSSISVDVPFYAHPKVLPFDKSKNLVQDESLVIE 621

Query: 157 CIATGRPEPTVTWRHISPKAV----------------GFVSEDEYLEIQGITREQSGEYE 200
           C   G P+P V+W   + + V                G   E   L I+ +  + +GEY 
Sbjct: 620 CKVLGYPKPVVSWYMDNVEIVDGADSRYSLKPANSYDGASIEGAKLVIEEVQFDDAGEYT 441

Query: 201 CSAS 204
           C ++
Sbjct: 440 CMSN 429
>11855
          Length = 1574

 Score = 32.7 bits (73), Expect = 0.19,   Method: Compositional matrix adjust.
 Identities = 42/133 (31%), Positives = 59/133 (44%), Gaps = 28/133 (21%)
 Frame = +1

Query: 109 DEGPYTCSVQTDNHPKTSRVH-LIVQV-----SPKIVEISSDISINE------------- 149
           DEG YTC  +T   P   RV   IV+V     SP +  +S   S  E             
Sbjct: 181 DEGEYTCVAET---PFKRRVQSTIVKVDTRHYSPDVTCMSKRGSRGEPARVYMWTVSRLE 351

Query: 150 --GNNISLTCIATGRPEPTVTW---RHIS-PKAVG--FVSEDEYLEIQGIT-REQSGEYE 200
                + L C A+G PEPT+TW   R+ S P   G   ++ +  L I+ I+  E  G Y 
Sbjct: 352 LETTTVQLFCRASGYPEPTITWYDGRNNSLPDNSGQFSIAVNGDLIIRDISWSENMGVYR 531

Query: 201 CSASNDVAAPVVR 213
           C A N++ +  V+
Sbjct: 532 CVAENELGSHSVQ 570
>12764
          Length = 1055

 Score = 32.3 bits (72), Expect = 0.27,   Method: Compositional matrix adjust.
 Identities = 25/86 (29%), Positives = 37/86 (43%), Gaps = 9/86 (10%)
 Frame = +1

Query: 133 QVSPKI-------VEISSDISI-NEGNNISLTCIATGRPEP-TVTWRHISPKAVGFVSED 183
           Q+SP+I       V ++ D     EG N+ LTCI  G P P  V WR         ++  
Sbjct: 196 QMSPQISVQYPVTVSVTPDTQQREEGLNLDLTCITQGNPLPFLVEWRQEGENTT--LATG 369

Query: 184 EYLEIQGITREQSGEYECSASNDVAA 209
             L +  ++   +G Y C+  N V  
Sbjct: 370 NTLTLTNLSLSDTGTYTCTGYNTVVG 447
>11732
          Length = 640

 Score = 29.6 bits (65), Expect = 2.0,   Method: Compositional matrix adjust.
 Identities = 17/71 (23%), Positives = 32/71 (45%)
 Frame = +2

Query: 100 IEIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVSPKIVEISSDISINEGNNISLTCIA 159
           +   ++ + D G Y C   +        + L V + P+I    S  ++ +G   ++ C+A
Sbjct: 50  LSFSDLSMDDAGLYQCKSTSGMEQVIRNITLFVVLEPQIKRNMSTFTMLDGIAEAV-CVA 226

Query: 160 TGRPEPTVTWR 170
            G P PT  +R
Sbjct: 227 EGDPAPTFLFR 259
>29881
          Length = 416

 Score = 29.3 bits (64), Expect = 2.3,   Method: Compositional matrix adjust.
 Identities = 22/66 (33%), Positives = 27/66 (40%), Gaps = 1/66 (1%)
 Frame = -3

Query: 238 KGTLQCEASAVPSAEFQWFKDDKRLVEG-KKGVKVENRPFLSKLTFFNVSEHDYGNYTCV 296
           KG      S   +    W KD     +G +K + V N   +S     NV E D G YTC 
Sbjct: 402 KGDSSVSVSGAQADVTMWRKDGDMFTQGPRKRMLVNNYLMVS-----NVVETDAGQYTCA 238

Query: 297 ASNKLG 302
           A N  G
Sbjct: 237 ARNSEG 220
>19453
          Length = 633

 Score = 28.5 bits (62), Expect = 3.8,   Method: Compositional matrix adjust.
 Identities = 12/26 (46%), Positives = 15/26 (57%)
 Frame = +1

Query: 105 VDVYDEGPYTCSVQTDNHPKTSRVHL 130
           +DV  EGP  CS+    HP + R HL
Sbjct: 235 LDVVSEGPLCCSLL*GTHPSSLRSHL 312
>16597
          Length = 419

 Score = 28.5 bits (62), Expect = 4.1,   Method: Compositional matrix adjust.
 Identities = 11/22 (50%), Positives = 14/22 (63%)
 Frame = -3

Query: 165 PTVTWRHISPKAVGFVSEDEYL 186
           PT TW  ++PK  G V E +YL
Sbjct: 306 PTATWCEVAPKPSGLVRERDYL 241
>20244
          Length = 452

 Score = 27.7 bits (60), Expect = 7.1,   Method: Compositional matrix adjust.
 Identities = 17/62 (27%), Positives = 28/62 (45%), Gaps = 3/62 (4%)
 Frame = -2

Query: 113 YTCSVQTDN--HPKTSRVHLIVQVSPK-IVEISSDISINEGNNISLTCIATGRPEPTVTW 169
           Y C + ++    P    V L V V+ + ++ +    S   G+ I+  C   G P P VTW
Sbjct: 241 YLCLLASNGLGEPVRREVELQVTVNAEAVIGLDPQNSYTPGSTIAFNCSVQGYPTPNVTW 62

Query: 170 RH 171
            +
Sbjct: 61  TN 56
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|33859662|ref|NP_036167.1| vesicle amine transport
protein 1 homolog (T californica) [Mus musculus]
         (406 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

05615                                                                  82   3e-16
02616                                                                  53   3e-07
00104                                                                  43   3e-04
25131                                                                  37   0.010
>05615
          Length = 1904

 Score = 82.4 bits (202), Expect = 3e-16,   Method: Compositional matrix adjust.
 Identities = 40/97 (41%), Positives = 59/97 (60%), Gaps = 3/97 (3%)
 Frame = +2

Query: 312 MAMARTWWNQFSVTALQLLQANRAVCGFHLGYL---DGEVELVNSVVTRLVALYNQGHIK 368
           +  +  WW    V  ++L   NR+V GF L  L    G+ + V+ VV +L+ L+ QG I+
Sbjct: 104 LTKSDQWWQVDKVNPIKLFDDNRSVGGFQLRRLLFRQGQHDYVHGVVDKLLELHGQGKIR 283

Query: 369 PRIDSVWPFEKVADAMKQMQEKKNIGKVLLVPGPEKE 405
           P IDSVW FE V + M+++ ++KNIGK+LL P  E E
Sbjct: 284 PVIDSVWAFEDVGEGMQKLHDRKNIGKILLDPSKEPE 394
>02616
          Length = 1048

 Score = 52.8 bits (125), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 52/178 (29%), Positives = 77/178 (43%), Gaps = 9/178 (5%)
 Frame = +1

Query: 230 VFGTASAS-KHEVLKENGVTHPIDYHTTDYVDEIKKISPKGVDIVMDPLGGSDTAKGYHL 288
           V GT S   K + LK  G   PI+Y   D    +K   P GV++V + +GG+      + 
Sbjct: 7   VIGTCSTDDKVQFLKSIGCDRPINYKKEDLGTVLKAEYPNGVNVVYESVGGAIFDTCLNN 186

Query: 289 LKPMGKVVTYGMANLLTGPKRNLMAMARTWWNQFSVTALQLLQANRAVCGFHLGYLDGEV 348
           L   G+++  G  +  T       A         S+  L  LQ + +V GF L +    V
Sbjct: 187 LAIGGRLMVIGAISGYTSDYSGFKAS--------SMLPLTXLQLSASVRGFFLMHF---V 333

Query: 349 ELVNSVVTRLVALYNQGHIKPRIDS-----VWPF---EKVADAMKQMQEKKNIGKVLL 398
                 +T+LV LY QG +   ID        PF    KV  A+  M   +NIGK+++
Sbjct: 334 RDFAEYMTKLVGLYQQGKVTTAIDMGEKSPDGPFVGLNKVNSAVDYMFSSQNIGKIVV 507
>00104
          Length = 1480

 Score = 42.7 bits (99), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 31/78 (39%), Positives = 42/78 (53%), Gaps = 3/78 (3%)
 Frame = -2

Query: 225  VENVTVFGTA-SASKHEVLKENGVTHPIDYHTTDYVDEIKKISPKGVDIVMDPLGG--SD 281
            V+  TV G+A S +K + LKE G  H  +Y  T   + +KK +P G+DI  D +GG  S 
Sbjct: 1467 VKGCTVIGSAGSQAKCDWLKELGFDHVFNYKETTVDEALKKFAPNGIDIHFDNVGGEFSY 1288

Query: 282  TAKGYHLLKPMGKVVTYG 299
            T    H LK   +VV  G
Sbjct: 1287 TVMSNH-LKFGARVVVCG 1237
>25131
          Length = 982

 Score = 37.4 bits (85), Expect = 0.010,   Method: Compositional matrix adjust.
 Identities = 24/76 (31%), Positives = 32/76 (42%), Gaps = 1/76 (1%)
 Frame = +2

Query: 119 LPVTPGMXXXXXXXXXXXXXXDRKAGDRVMVLNR-SGMWQEEVTVPSAQTFLMPEAMTFE 177
           LP TPG               D K GDR   +   +G + E        T  + + ++F 
Sbjct: 2   LPYTPGSDAAGVVESVGXKVKDFKKGDRAYTIRSVTGTYGEYAVSEVVHTARLSDKLSFS 181

Query: 178 EAAALLVNYITAYMVL 193
           + AAL V Y TAY  L
Sbjct: 182 QGAALGVPYYTAYRAL 229
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|7106381|ref|NP_035992.1| protein kinase C and casein
kinase substrate in neurons 2 [Mus musculus]
         (486 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

17800                                                                  82   3e-16
14893                                                                  73   3e-13
28095                                                                  51   1e-06
16716                                                                  49   5e-06
29687                                                                  48   9e-06
12324                                                                  47   1e-05
01494                                                                  47   2e-05
30482                                                                  44   2e-04
13664                                                                  39   0.005
15115                                                                  37   0.013
26032                                                                  37   0.021
30899                                                                  33   0.20 
19469                                                                  33   0.35 
05206                                                                  32   0.58 
08823                                                                  31   1.1  
31183                                                                  30   2.0  
>17800
          Length = 451

 Score = 82.4 bits (202), Expect = 3e-16,   Method: Compositional matrix adjust.
 Identities = 41/110 (37%), Positives = 57/110 (51%)
 Frame = +2

Query: 222 YMENMXXXXXXXXXXXXKRLRFFREVLLEVQKHLDLSNVASYKTIYRELEQSIKAADAVE 281
           Y+E+M             RL+FF+EVL  V   LD + V S   IY E   +I  AD  +
Sbjct: 23  YIEDMTSVFEKCQTMEKTRLQFFKEVLFNVHSTLDTTKVQSLPQIYDEFYHTINNADQQK 202

Query: 282 DLRWFRANHGPGMAMNWPQFEEWSADLNRTLSRREKKKAVDGVTLTGINQ 331
           DL+W+  NHG  MAMNWP F E++ +        + K+A+    +T INQ
Sbjct: 203 DLKWWSNNHGINMAMNWPAFVEYTEEFRDIAKGNKSKEALPAAPITLINQ 352
>14893
          Length = 403

 Score = 72.8 bits (177), Expect = 3e-13,   Method: Compositional matrix adjust.
 Identities = 38/118 (32%), Positives = 62/118 (52%), Gaps = 3/118 (2%)
 Frame = +1

Query: 222 YMENMXXXXXXXXXXXXKRLRFFREVLLEVQKHLDLSNVASYKTIYRELEQSIKAADAVE 281
           Y+E+M             R+ FF+    ++ K LDLS  + Y  +Y +L  +I   D   
Sbjct: 1   YIEDMTEVYDKCQEFERTRIEFFKATFFKLHKCLDLSVESEYARVYTDLHATITNTDPDR 180

Query: 282 DLRWFRANHGPGMAMNWPQFEEWSADLNRTLSRREKKKAVD---GVTLTGINQTGDQS 336
           DL+++  +HG  MAM WPQFEE+S +L + +S++ K        G+T+T I  + + S
Sbjct: 181 DLKYWSTSHGIDMAMAWPQFEEYSPEL-QAISKKGKGAVSTGEGGITITSIRHSRESS 351
>28095
          Length = 597

 Score = 50.8 bits (120), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 24/56 (42%), Positives = 37/56 (66%), Gaps = 1/56 (1%)
 Frame = +3

Query: 431 VRALYDYEGQEHDELSFKAGDELTKIEDEDEQGWCKGRLD-SGQVGLYPANYVEAI 485
            +A+YDY+  + DE+SF  GD + + +  D  GW  GR++ +GQ G+ P+NYVE I
Sbjct: 264 CKAMYDYQAADSDEVSFNDGDTIIECQPVD-AGWMTGRVERTGQYGMLPSNYVERI 428
>16716
          Length = 934

 Score = 48.5 bits (114), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 27/54 (50%), Positives = 35/54 (64%)
 Frame = -1

Query: 433 ALYDYEGQEHDELSFKAGDELTKIEDEDEQGWCKGRLDSGQVGLYPANYVEAIQ 486
           ALYDY+  + DEL+F   D +T IE  D+ GW +G    G+ GL+PANYVE  Q
Sbjct: 457 ALYDYQAADDDELTFDPDDVITDIEMIDD-GWWRGSC-HGKNGLFPANYVELQQ 302
>29687
          Length = 434

 Score = 47.8 bits (112), Expect = 9e-06,   Method: Compositional matrix adjust.
 Identities = 24/59 (40%), Positives = 37/59 (62%)
 Frame = -2

Query: 427 TEVRVRALYDYEGQEHDELSFKAGDELTKIEDEDEQGWCKGRLDSGQVGLYPANYVEAI 485
           T++RV+AL+DY  +  DELSF  G  +T +  +D  GW +G   + +   +P+NYVE I
Sbjct: 304 TKLRVKALHDYNAKREDELSFCKGAIITNVSRQD-GGWWRGDYGTKKQHWFPSNYVEEI 131
>12324
          Length = 946

 Score = 47.4 bits (111), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 32/93 (34%), Positives = 50/93 (53%), Gaps = 5/93 (5%)
 Frame = +3

Query: 396 TDWSDDESNNPFSSTD----ANGDSNPFDEDTTSGTEV-RVRALYDYEGQEHDELSFKAG 450
           +D  D +SN P +  +    A G      ++    T + +V A+YDYE ++ DEL+F   
Sbjct: 576 SDHGDGDSNPPAAPPEDPYAATGPGFLGPDEYMPATYIEKVVAIYDYEAEKDDELTFSEN 755

Query: 451 DELTKIEDEDEQGWCKGRLDSGQVGLYPANYVE 483
             +  I   D+ GW +G +D G  GL+P+NYVE
Sbjct: 756 SVIYVIRKNDD-GWWEGVMD-GVTGLFPSNYVE 848
>01494
          Length = 2122

 Score = 46.6 bits (109), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 23/60 (38%), Positives = 37/60 (61%)
 Frame = +3

Query: 427 TEVRVRALYDYEGQEHDELSFKAGDELTKIEDEDEQGWCKGRLDSGQVGLYPANYVEAIQ 486
           T++RV+AL+DY     DELSF  G  +T +  +D  GW +G   + +   +P+N+VE I+
Sbjct: 300 TKLRVKALHDYNANRDDELSFCKGAIITNVSRQD-GGWWRGDYGAKKQHWFPSNFVEEIE 476
>30482
          Length = 610

 Score = 43.5 bits (101), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 25/78 (32%), Positives = 39/78 (50%), Gaps = 3/78 (3%)
 Frame = +3

Query: 409 STDANGDSNPFDEDTTSGTEVRVRALYDYEGQEHDELSFKAGDELTKIEDEDEQG---WC 465
           + D  G ++PF    +   + R RAL+ +E +  DEL+   GD++   +   E G   W 
Sbjct: 66  TADVWGTTDPF-AGGSGIKKTRYRALFPFESRSEDELNINTGDDIWVWDVPSEPGMEEWF 242

Query: 466 KGRLDSGQVGLYPANYVE 483
           KG    G+VG +P  Y E
Sbjct: 243 KGETKDGKVGWFPQAYAE 296
>13664
          Length = 507

 Score = 38.9 bits (89), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 19/47 (40%), Positives = 27/47 (57%)
 Frame = +2

Query: 430 RVRALYDYEGQEHDELSFKAGDELTKIEDEDEQGWCKGRLDSGQVGL 476
           +V ALYDY+ Q  DEL+  +GD +  +  +D + W  G L  GQ G 
Sbjct: 368 KVVALYDYKAQRSDELTILSGDVIMLLH-KDSESWWMGELLDGQQGF 505
>15115
          Length = 443

 Score = 37.4 bits (85), Expect = 0.013,   Method: Composition-based stats.
 Identities = 18/49 (36%), Positives = 29/49 (59%)
 Frame = -2

Query: 437 YEGQEHDELSFKAGDELTKIEDEDEQGWCKGRLDSGQVGLYPANYVEAI 485
           ++  +  E++F   D +T I+  DE GW +G    G  G++PANYVE +
Sbjct: 433 HQAGDDTEITFDPDDIITNIDQIDE-GWWQGFAPDGSYGMFPANYVELL 290
>26032
          Length = 465

 Score = 36.6 bits (83), Expect = 0.021,   Method: Composition-based stats.
 Identities = 21/54 (38%), Positives = 30/54 (55%)
 Frame = +2

Query: 432 RALYDYEGQEHDELSFKAGDELTKIEDEDEQGWCKGRLDSGQVGLYPANYVEAI 485
           R   D+E  + DEL F+  D +T I  +DE  W  G L+ G  G +PA +VE +
Sbjct: 17  RLF*DFERHDDDELGFRKNDIITLISQKDEHCWI-GELN-GLRGWFPAKFVEVL 172
>30899
          Length = 698

 Score = 33.5 bits (75), Expect = 0.20,   Method: Compositional matrix adjust.
 Identities = 23/53 (43%), Positives = 30/53 (56%), Gaps = 3/53 (5%)
 Frame = -2

Query: 400 DDESNNPFSSTDANGDSNPFDEDTT--SGTEVR-VRALYDYEGQEHDELSFKA 449
           D E + P +S      S P   DTT     E+R VRALYD+E  E +EL+F+A
Sbjct: 160 DAEKSQPKASGSLYPVSYPTMADTTYNKPKELRKVRALYDFEAAEDNELTFQA 2
>19469
          Length = 428

 Score = 32.7 bits (73), Expect = 0.35,   Method: Compositional matrix adjust.
 Identities = 20/58 (34%), Positives = 32/58 (55%), Gaps = 4/58 (6%)
 Frame = -1

Query: 432 RALYDYEGQEHDELSFKAGDELTKIEDEDE--QGW--CKGRLDSGQVGLYPANYVEAI 485
           +ALYD   +  DEL+F+ GD +T +E +     GW  C  R   G+ G+ P N ++ +
Sbjct: 356 KALYDNIAETPDELAFRRGDVITILEQDTAGLDGWWLCSLR---GRQGIAPGNRLKIL 192
>05206
          Length = 1075

 Score = 32.0 bits (71), Expect = 0.58,   Method: Compositional matrix adjust.
 Identities = 20/73 (27%), Positives = 33/73 (45%)
 Frame = +1

Query: 412 ANGDSNPFDEDTTSGTEVRVRALYDYEGQEHDELSFKAGDELTKIEDEDEQGWCKGRLDS 471
            +GD +   E    GT    RALY +E      +     +E+  +E++   GW + R   
Sbjct: 49  GDGDLDGEGEFIVIGT---CRALYPFEAMNEGSVPMGENEEMQILEEDQGDGWTRVRKAD 219

Query: 472 GQVGLYPANYVEA 484
           G  G  P++YV+ 
Sbjct: 220 GSEGFVPSSYVQC 258
>08823
          Length = 675

 Score = 31.2 bits (69), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 22/65 (33%), Positives = 32/65 (49%)
 Frame = +1

Query: 398 WSDDESNNPFSSTDANGDSNPFDEDTTSGTEVRVRALYDYEGQEHDELSFKAGDELTKIE 457
           +S   +N PFS T        F +  T+    R RAL + E Q+ DEL  K  DE  K E
Sbjct: 349 YSLVRANKPFSITQQAEFVRSFRDQWTT----RARALMEAERQKKDELKQKREDEFLKRE 516

Query: 458 DEDEQ 462
           ++ ++
Sbjct: 517 EKRQK 531
>31183
          Length = 923

 Score = 30.0 bits (66), Expect = 2.0,   Method: Compositional matrix adjust.
 Identities = 18/36 (50%), Positives = 23/36 (63%)
 Frame = +1

Query: 451 DELTKIEDEDEQGWCKGRLDSGQVGLYPANYVEAIQ 486
           D +T IE  D+ GW +G    G+ GL+PANYVE  Q
Sbjct: 4   DVITDIEMIDD-GWWRGSC-HGKNGLFPANYVELQQ 105
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|157951596|ref|NP_033931.4| carbonic anhydrase II [Mus
musculus]
         (260 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

25693                                                                  81   5e-16
35985                                                                  58   4e-09
17466                                                                  42   2e-04
17230                                                                  41   6e-04
20281                                                                  31   0.60 
34904                                                                  28   3.3  
>25693
          Length = 428

 Score = 80.9 bits (198), Expect = 5e-16,   Method: Compositional matrix adjust.
 Identities = 49/134 (36%), Positives = 71/134 (52%), Gaps = 19/134 (14%)
 Frame = -2

Query: 20  FPIANGDRQSPVDIDTATAQHDPAL--QPLLISYDKAASKSIVNNGHSFNV----EFDDS 73
            P A G RQSPVD+ +  A+++  L   PL  +Y  +    I+NNG++  V    +  +S
Sbjct: 403 LPEATGSRQSPVDVVSCDAKYEELLANTPLQFNYATSRETDILNNGYTLVVFPRAKQVES 224

Query: 74  QDN----------AVLKGGPLSD--SYRLIQFHFHWGSSDGQGSEHTVNKKKYAAELHLV 121
           Q +          + + GGPL     Y L +  FHWG  + +GSEHTVN K +  E+ LV
Sbjct: 223 QTSHRADLASHTASSVSGGPLPQGMEYELAEIRFHWGRENSRGSEHTVNNKAFPMEVQLV 44

Query: 122 HWNTK-YGDFGKAV 134
           HWNT+ Y    +AV
Sbjct: 43  HWNTRLYESIEEAV 2
>35985
          Length = 475

 Score = 57.8 bits (138), Expect = 4e-09,   Method: Compositional matrix adjust.
 Identities = 45/114 (39%), Positives = 60/114 (52%), Gaps = 4/114 (3%)
 Frame = +3

Query: 5   WGYSKHNGPENWHKDFPIA-NGDRQSPVDIDTATAQHDPALQPLLISYDK---AASKSIV 60
           W Y  HNGP +WH+ FP A +G  QSP+DI  A  + D  L    I YD     AS  + 
Sbjct: 108 WSYEGHNGPHHWHQLFPQACSGKYQSPIDIQPADTRFDSNLNDFAIWYDPPRPGASMVVS 287

Query: 61  NNGHSFNVEFDDSQDNAVLKGGPLSDSYRLIQFHFHWGSSDGQGSEHTVNKKKY 114
           NNGH+  V    ++    +  G L   YR  QFHFHWG +   GSEH ++ + +
Sbjct: 288 NNGHTVQVL---TKGELYVANGGLPYVYRATQFHFHWGHAHHHGSEHLIDNQAF 440
>17466
          Length = 513

 Score = 42.0 bits (97), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 29/95 (30%), Positives = 49/95 (51%), Gaps = 3/95 (3%)
 Frame = -1

Query: 5   WGYSKHNGPENWHKDFPIANGDRQSPVDIDTATAQHDPALQPLLISYDKAASKSIVN-NG 63
           W YS+  GP  W   FP  +G RQSPV+I+ +  Q+    Q   ++ D   +   V+ +G
Sbjct: 273 WDYSQGKGPVAWPFKFPACSGLRQSPVNIERSRVQYGMMGQVDPVNVDILTNLFFVSYDG 94

Query: 64  HSFNVEFDDSQDNAVLKG--GPLSDSYRLIQFHFH 96
            +  +     +D  +++G  GP  D++ +  FHFH
Sbjct: 93  ATMYIR---PKDRLLVQGIRGP-RDTHAVHNFHFH 1
>17230
          Length = 486

 Score = 40.8 bits (94), Expect = 6e-04,   Method: Compositional matrix adjust.
 Identities = 27/85 (31%), Positives = 41/85 (48%), Gaps = 4/85 (4%)
 Frame = +3

Query: 5   WGYSKHNGPENWHKDFPIANGDRQSPVDIDTATAQHDPALQPLLIS--YDKAASKSIVNN 62
           +GY    GP++W  D+   +G  QSP++I+           PL     Y++     I NN
Sbjct: 225 FGYGGPIGPDHWRDDYQQCSGKYQSPININVLNVTKK-EFPPLTYENFYERPEEILITNN 401

Query: 63  GHSFNV--EFDDSQDNAVLKGGPLS 85
           GH+  V  +F   ++  V KGGPL 
Sbjct: 402 GHTVLVTMKFKKGKEPRV-KGGPLE 473
>20281
          Length = 770

 Score = 30.8 bits (68), Expect = 0.60,   Method: Compositional matrix adjust.
 Identities = 12/24 (50%), Positives = 17/24 (70%)
 Frame = -1

Query: 237 EEAMVDNWRPAQPLKNRKIKASFK 260
           +E +V+N+RP QPL  R +  SFK
Sbjct: 647 QEVIVNNFRPVQPLNGRLVYRSFK 576
>34904
          Length = 776

 Score = 28.1 bits (61), Expect = 3.3,   Method: Compositional matrix adjust.
 Identities = 12/41 (29%), Positives = 20/41 (48%)
 Frame = -3

Query: 141 AVLGIFLKIGPASQGLQKVLEALHSIKTKGKRAAFANFDPC 181
            ++ IFLK+G     + KV +  +S   + K+    N  PC
Sbjct: 204 TIITIFLKLGTTPNRIGKVRKVSYS*SCENKKTHITNMTPC 82
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|13385798|ref|NP_080578.1| dynactin 4 [Mus musculus]
         (460 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

30580                                                                  64   6e-16
22266                                                                  29   3.6  
09201                                                                  28   7.5  
>30580
          Length = 576

 Score = 63.5 bits (153), Expect(2) = 6e-16,   Method: Compositional matrix adjust.
 Identities = 32/72 (44%), Positives = 46/72 (63%)
 Frame = +2

Query: 385 FQDDPDIVAFRKANKVGIFIKVTPQREEGEVTVCFKMKHDFKNLAAPIRPVEEGDQGTEV 444
           F+DDP IV FR+ANK+G   KVTP  + G+V V F MKH+++N AA I   +  D+  ++
Sbjct: 287 FKDDPRIVVFRRANKIGFAAKVTPFCKNGDVKVSFLMKHEYRNSAAAI---QSDDKEPKL 457

Query: 445 IWLTQHVELSFG 456
            WL   + L+ G
Sbjct: 458 EWLEHRLFLNLG 493

 Score = 38.5 bits (88), Expect(2) = 6e-16,   Method: Compositional matrix adjust.
 Identities = 25/65 (38%), Positives = 37/65 (56%)
 Frame = +3

Query: 319 YMKESQVLLTLTNPVENLTHVTLLECDEGDPDNINSTAKVVVPPKELILAGKDAAAEYDE 378
           + K++ V  TL+NP    T V L+   EGD D    TAK+ +P  +L+LA  D  A YD+
Sbjct: 87  FNKDTVVTFTLSNPSVYNTVVKLMPI-EGDTDLDYMTAKIDLPKCDLVLAHHDDTAVYDD 263

Query: 379 LAEPQ 383
            ++ Q
Sbjct: 264 SSKAQ 278
>22266
          Length = 523

 Score = 29.3 bits (64), Expect = 3.6,   Method: Compositional matrix adjust.
 Identities = 13/36 (36%), Positives = 19/36 (52%)
 Frame = +2

Query: 11 LYLVQGEKKVRAPLSQLYFCRYCSELRSLECVSHEV 46
          LYL+     +  P  +LY C +C ++  L CV H V
Sbjct: 8  LYLLGFNIYLYVPSLKLYMCLFCKDMYILLCVFHFV 115
>09201
          Length = 754

 Score = 28.1 bits (61), Expect = 7.5,   Method: Compositional matrix adjust.
 Identities = 13/30 (43%), Positives = 19/30 (63%)
 Frame = -1

Query: 140 HTQRMNKLIEYYQQLAQKEKVERDRKKLAR 169
           HTQ +NK+    QQ+++ E+V R R   AR
Sbjct: 439 HTQSINKIRSQSQQMSENERVYRQRLDSAR 350
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|149270526|ref|XP_283556.7| PREDICTED: myoferlin
isoform 1 [Mus musculus]
         (2048 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

26488                                                                  84   6e-16
29179                                                                  48   4e-05
30040                                                                  39   0.022
07591                                                                  36   0.13 
32719                                                                  36   0.15 
36305                                                                  35   0.30 
29411                                                                  32   3.1  
14539                                                                  32   3.8  
26525                                                                  26   5.4  
01494                                                                  30   8.2  
>26488
          Length = 399

 Score = 84.0 bits (206), Expect = 6e-16,   Method: Compositional matrix adjust.
 Identities = 38/77 (49%), Positives = 51/77 (66%), Gaps = 1/77 (1%)
 Frame = +3

Query: 867 VGRHKFSDVTGKIKLKREFFLPPKGWEWEGDWVVDPERSLLTEADAGHTEFTDEVYQNEN 926
           + R KFSD  G +KL +E F PP GW+WE DW + PE S+L + DAGH  F ++VY+ ++
Sbjct: 21  MSRPKFSDSEGNVKLPKEGFTPPAGWQWEADWYISPELSMLFDRDAGHRTFMEDVYECQS 200

Query: 927 R-YPGGEWKQAEDTYTD 942
           R  PGG W QA   +TD
Sbjct: 201 RNIPGGSWGQASRPWTD 251
>29179
          Length = 1113

 Score = 47.8 bits (112), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 35/111 (31%), Positives = 54/111 (48%), Gaps = 13/111 (11%)
 Frame = -3

Query: 1538 QECTVRIYIVQGLQLQPQDNNGLCDPYIKITLGKKVIEDRDHYI-----PNTLNPVFGRM 1592
            Q  T+ + I++ + L  +D  G  DPY+KI L    + D+ H +        LNP +   
Sbjct: 505  QNLTLTLRIIRAVDLPAKDVTGTSDPYVKILL----LPDKKHKLLTKVKKRNLNPHWN-- 344

Query: 1593 YELSCYLPQ--------EKDLKISVYDYDTFTRDEKVGETTIDLENRFLSR 1635
                C+L +        EK L + V DYD F+RD+ +GET + L    LS+
Sbjct: 343  ---ECFLFEGWPHNKLLEKTLYLQVIDYDRFSRDDPIGETYLPLNEIDLSQ 200

 Score = 47.8 bits (112), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 35/113 (30%), Positives = 59/113 (52%), Gaps = 6/113 (5%)
 Frame = -3

Query: 358 VTFMLKIYRAEDIPQMDDAFSQTVKEIFGGNADKKNLVDPFVEVSF---AGKKVCTNIIE 414
           +T  L+I RA D+P          K++ G +       DP+V++        K+ T + +
Sbjct: 499 LTLTLRIIRAVDLP---------AKDVTGTS-------DPYVKILLLPDKKHKLLTKVKK 368

Query: 415 RNANPEWNQVVNLQIKFP--SMCEK-IKLTVYDWDRLTKNDVVGTTYLYLSKI 464
           RN NP WN+    +  +P   + EK + L V D+DR +++D +G TYL L++I
Sbjct: 367 RNLNPHWNECFLFE-GWPHNKLLEKTLYLQVIDYDRFSRDDPIGETYLPLNEI 212

 Score = 36.6 bits (83), Expect = 0.11,   Method: Compositional matrix adjust.
 Identities = 41/165 (24%), Positives = 76/165 (46%), Gaps = 9/165 (5%)
 Frame = -3

Query: 1098 PEKQKHSAT--TVFGANTPIVSCNFDRVYIYH---LRCYIYQARNLMALDKDSFSDPYAH 1152
            PE  +  AT   V G +  +    F  +Y +    L   I +A +L A D    SDPY  
Sbjct: 598  PEVVEEHATGPIVEGVDYKLGRIQFGLMYDFQNLTLTLRIIRAVDLPAKDVTGTSDPYVK 419

Query: 1153 VSFLHRSK---TTEIIHSTLNPTWDQTIIFDEVEIFGEPQTVLQNPPNVTIELFDNDQVG 1209
            +  L   K    T++    LNP W++  +F+     G P   L     + +++ D D+  
Sbjct: 418  ILLLPDKKHKLLTKVKKRNLNPHWNECFLFE-----GWPHNKLLE-KTLYLQVIDYDRFS 257

Query: 1210 KDEFLGRSICSPLVKLN-SETDITPKLLWHPVMNGDKACGDVLVT 1253
            +D+ +G +   PL +++ S++ ++ K L  P  +     G++L++
Sbjct: 256  RDDPIGETYL-PLNEIDLSQSPVSWKYL-QPCKDTRGKLGELLLS 128
>30040
          Length = 652

 Score = 38.9 bits (89), Expect = 0.022,   Method: Composition-based stats.
 Identities = 26/98 (26%), Positives = 47/98 (47%), Gaps = 7/98 (7%)
 Frame = -3

Query: 1128 LRCYIYQARNLMALDKDSFSDPYAHVSFLH-----RSKTTEIIHSTLNPTWDQTIIFDEV 1182
            L   + +A++L        +DP+  VS L      + K T +  +++NP W++ + F+  
Sbjct: 611  LTVVLMKAKDLKMSTSHPSADPFVRVSLLVEGKKVKRKKTSVRRASINPVWNEALAFN-- 438

Query: 1183 EIFGEPQTVLQNPPNVTIE--LFDNDQVGKDEFLGRSI 1218
                 P  VL   P VT+E  + D+D +G  + LG  +
Sbjct: 437  ----VPAEVL---PKVTLEVSVLDHDLIGHGDVLGTCV 345

 Score = 31.2 bits (69), Expect = 4.4,   Method: Composition-based stats.
 Identities = 19/68 (27%), Positives = 35/68 (51%), Gaps = 3/68 (4%)
 Frame = -3

Query: 42  LNPVWNEILEFDLRGIPLDSSSSLVIVVKDFETIGQNKLIGTATVSL---KDLIGDQNRS 98
           +NPVWNE L F++    L    +L + V D + IG   ++GT  +      D +G  N  
Sbjct: 473 INPVWNEALAFNVPAEVL-PKVTLEVSVLDHDLIGHGDVLGTCVLGAGCGGDELGHWNEM 297

Query: 99  LPYKQTSL 106
           + +++ ++
Sbjct: 296 MLHQRKTI 273
>07591
          Length = 796

 Score = 36.2 bits (82), Expect = 0.13,   Method: Compositional matrix adjust.
 Identities = 32/123 (26%), Positives = 53/123 (43%), Gaps = 14/123 (11%)
 Frame = +2

Query: 347 LLLPAGIALRWVTFMLKIYRAEDIPQMDDAFSQTVKEIFGGNADKKNLV---DPFVEVSF 403
           L+LP+G   R     +   RAE++ +     + T         DKK+ +   DP++EV  
Sbjct: 380 LVLPSG---RRAGNGVITVRAEELKEGTGNVAMT---FHAKKLDKKDFLGKSDPYLEVLR 541

Query: 404 AGKKVC------TNIIERNANPEWNQVVNLQIKFPSMC-----EKIKLTVYDWDRLTKND 452
           A           T +++ N NP W      ++   ++C     + IK  VYDWD    +D
Sbjct: 542 ATSDGSWQMVHRTEVVKNNLNPSWRP---FELSMQTLCGGNHQQNIKFDVYDWDSDGSHD 712

Query: 453 VVG 455
            +G
Sbjct: 713 YIG 721
>32719
          Length = 348

 Score = 36.2 bits (82), Expect = 0.15,   Method: Composition-based stats.
 Identities = 21/65 (32%), Positives = 35/65 (53%), Gaps = 2/65 (3%)
 Frame = +2

Query: 65  LVIVVKDFETIGQNKLIGTATVSLKDLIGDQN--RSLPYKQTSLLNEKGQDTGATIDLVI 122
           LV+ V D+E +G+N+ +GTA V L   +G     R L  K   L++   +   A +++ +
Sbjct: 8   LVVSVFDWERVGRNRQLGTAQVQLGQFLGGGQVARQLEVK---LMDGSQRPLAAVLNIKV 178

Query: 123 GYTPP 127
            Y PP
Sbjct: 179 TYNPP 193
>36305
          Length = 586

 Score = 35.0 bits (79), Expect = 0.30,   Method: Compositional matrix adjust.
 Identities = 20/69 (28%), Positives = 34/69 (49%)
 Frame = -1

Query: 396 DPFVEVSFAGKKVCTNIIERNANPEWNQVVNLQIKFPSMCEKIKLTVYDWDRLTKNDVVG 455
           DP+  V+   +   T +I+    P WN+V    I      + +KL + D D   K+D +G
Sbjct: 574 DPYTVVTVGAQTFKTKVIDDTVEPRWNEVFEFVID-ERDGQILKLNISDKDPGNKDDPLG 398

Query: 456 TTYLYLSKI 464
           +T + +S I
Sbjct: 397 STTMDISTI 371
>29411
          Length = 563

 Score = 31.6 bits (70), Expect = 3.1,   Method: Composition-based stats.
 Identities = 22/68 (32%), Positives = 30/68 (44%)
 Frame = +3

Query: 39  DNELNPVWNEILEFDLRGIPLDSSSSLVIVVKDFETIGQNKLIGTATVSLKDLIGDQNRS 98
           +N L+P W E  EFD+    L     +  VV D   + +N  +G A + L     D   S
Sbjct: 30  ENTLDPQWEETFEFDVALEELSFRYVVFHVVDDTTILSENHSMGQAILDL-----DVMES 194

Query: 99  LPYKQTSL 106
            P   TSL
Sbjct: 195 QPSFHTSL 218
>14539
          Length = 436

 Score = 31.6 bits (70), Expect = 3.8,   Method: Compositional matrix adjust.
 Identities = 23/66 (34%), Positives = 30/66 (45%)
 Frame = +3

Query: 38  VDNELNPVWNEILEFDLRGIPLDSSSSLVIVVKDFETIGQNKLIGTATVSLKDLIGDQNR 97
           VDN LNPVWN+   FD+    L   + L   V D +T G    +G     +   I    R
Sbjct: 150 VDNGLNPVWNKNCVFDVLCPEL---ALLRFAVMDEDTFGDPNFLGQGCFPVP-CIKSGFR 317

Query: 98  SLPYKQ 103
           S+P K 
Sbjct: 318 SVPLKN 335
>26525
          Length = 455

 Score = 26.2 bits (56), Expect(2) = 5.4,   Method: Composition-based stats.
 Identities = 15/44 (34%), Positives = 25/44 (56%), Gaps = 2/44 (4%)
 Frame = +1

Query: 1552 LQPQDNN-GLCDPYIKIT-LGKKVIEDRDHYIPNTLNPVFGRMY 1593
            L P+D + G CDPY+K+  L +K  + +   +  TLNP +   +
Sbjct: 4    LPPRDPSLGGCDPYVKLQLLPEKKHKCKTRVVRKTLNPKYDETF 135

 Score = 23.1 bits (48), Expect(2) = 5.4,   Method: Compositional matrix adjust.
 Identities = 9/22 (40%), Positives = 13/22 (59%)
 Frame = +3

Query: 1609 VYDYDTFTRDEKVGETTIDLEN 1630
            V  +D F+RDE +GE    L +
Sbjct: 189  VLSFDRFSRDEIIGEVIYPLSD 254
>01494
          Length = 2122

 Score = 30.4 bits (67), Expect = 8.2,   Method: Compositional matrix adjust.
 Identities = 18/47 (38%), Positives = 22/47 (46%)
 Frame = +1

Query: 38   VDNELNPVWNEILEFDLRGIPLDSSSSLVIVVKDFETIGQNKLIGTA 84
            VDN LNPVWNE   FD   +     + L   V D +  G    +G A
Sbjct: 1291 VDNGLNPVWNENCVFD---VLCPEMALLRFAVMDEDIFGDPNFLGQA 1422
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31981086|ref|NP_080270.2| EF hand domain containing 2
[Mus musculus]
         (240 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

35350                                                                  80   6e-16
14594                                                                  32   0.23 
20251                                                                  31   0.45 
01773                                                                  29   2.1  
15966                                                                  29   2.2  
>35350
          Length = 339

 Score = 80.5 bits (197), Expect = 6e-16,   Method: Compositional matrix adjust.
 Identities = 41/67 (61%), Positives = 46/67 (68%)
 Frame = +2

Query: 125 GAPQTHLGLKSMIQEVDEDFDSKLSFREFLLIFRKAAAGELQEDSGLHVLARLSEIDVST 184
           GAPQTHLGLK MI EVDED DSK+SFREFLLI+RKA A  + +  G   +     IDV  
Sbjct: 38  GAPQTHLGLKKMIAEVDEDHDSKISFREFLLIYRKAQAWRIGQ*IGSQSVGSTHRIDVEQ 217

Query: 185 EGVKGAK 191
            GV GAK
Sbjct: 218 VGVSGAK 238
>14594
          Length = 1014

 Score = 32.0 bits (71), Expect = 0.23,   Method: Compositional matrix adjust.
 Identities = 22/81 (27%), Positives = 37/81 (45%), Gaps = 1/81 (1%)
 Frame = +3

Query: 89  FSRKQIKDMEKMFKQYDAGRDGFIDXXXXXXXXXXXGAPQTHLGLKSMIQEVDEDFDSKL 148
            + +Q+ + ++ F  +D   DG I            G   T   L+ MI EVD D +  +
Sbjct: 423 LTDEQVAEFKEAFSLFDKDGDGTITTSELGTVMRSLGQNPTENELQDMINEVDADGNGTI 602

Query: 149 SFREFL-LIFRKAAAGELQED 168
            F EFL ++ RK    + +E+
Sbjct: 603 DFEEFLHMMARKMKDTDCEEE 665
>20251
          Length = 2203

 Score = 30.8 bits (68), Expect = 0.45,   Method: Compositional matrix adjust.
 Identities = 25/94 (26%), Positives = 35/94 (37%)
 Frame = +3

Query: 86  FKEFSRKQIKDMEKMFKQYDAGRDGFIDXXXXXXXXXXXGAPQTHLGLKSMIQEVDEDFD 145
           F  F + QI++ ++ F   D  RDGFID           G   T   L  M+        
Sbjct: 132 FAMFDQSQIQEFKEAFNMIDQNRDGFIDKEDLGDMLASLGKNPTEGQLDEMMNXA----P 299

Query: 146 SKLSFREFLLIFRKAAAGELQEDSGLHVLARLSE 179
             ++F  FL +F     G   ED   +  A   E
Sbjct: 300 GPINFTMFLTMFGDKLNGTDPEDVIKNAFACFDE 401
>01773
          Length = 1950

 Score = 28.9 bits (63), Expect = 2.1,   Method: Compositional matrix adjust.
 Identities = 14/61 (22%), Positives = 31/61 (50%)
 Frame = +1

Query: 94  IKDMEKMFKQYDAGRDGFIDXXXXXXXXXXXGAPQTHLGLKSMIQEVDEDFDSKLSFREF 153
           ++ + ++FK  D   DG++D           G   T   + ++++  D++ D+K+ F EF
Sbjct: 364 VQKLAELFKAKDKSGDGYLDRDELKALLDESGQKFTADDVSAILKSADKNNDNKICFEEF 543

Query: 154 L 154
           +
Sbjct: 544 V 546
>15966
          Length = 362

 Score = 28.9 bits (63), Expect = 2.2,   Method: Compositional matrix adjust.
 Identities = 14/61 (22%), Positives = 31/61 (50%)
 Frame = +2

Query: 94  IKDMEKMFKQYDAGRDGFIDXXXXXXXXXXXGAPQTHLGLKSMIQEVDEDFDSKLSFREF 153
           ++ + ++FK  D   DG++D           G   T   + ++++  D++ D+K+ F EF
Sbjct: 131 VQKLAELFKAKDKSGDGYLDRDELKALLDESGQKFTADDVSAILKSADKNNDNKICFEEF 310

Query: 154 L 154
           +
Sbjct: 311 V 313
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6755674|ref|NP_035620.1| staufen (RNA binding
protein) homolog 1 isoform 3 [Mus musculus]
         (487 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

04944                                                                  82   6e-16
05371                                                                  45   5e-05
25595                                                                  28   5.9  
>04944
          Length = 863

 Score = 81.6 bits (200), Expect = 6e-16,   Method: Compositional matrix adjust.
 Identities = 51/93 (54%), Positives = 61/93 (65%), Gaps = 2/93 (2%)
 Frame = +2

Query: 41  VELSVGGQQFNGKGKMRPPVKHDAPARALRTLQSEPLPERLEVNGREAEEENLN--KSEI 98
           V L VG ++F G G  R   +H+A  +AL+ L+  P P        E EEE+ N  KSEI
Sbjct: 446 VMLKVGPKEFIGDGPTRQAARHNAATKALKILKILPTPADAGKTPAEEEEESENGIKSEI 625

Query: 99  SQVFEIALKRNLPVNFEVARESGPPHMKNFVTR 131
           S V E+ALKRNLPV FEV RESGPPHMKNFVT+
Sbjct: 626 SLVHEMALKRNLPVAFEVVRESGPPHMKNFVTK 724
>05371
          Length = 1247

 Score = 45.4 bits (106), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 30/71 (42%), Positives = 41/71 (57%), Gaps = 1/71 (1%)
 Frame = +2

Query: 196 NPISRLAQIQQAKKEKEPEYMLLTERGLPRRREFVMQVKVGHHTAEGVGTNKKVAKRNAA 255
            PIS L Q    K+   P+Y LL+  G      F+M+V V  ++AEG GT+KK AK +AA
Sbjct: 5   TPISYL-QEYCTKRNLTPDYQLLSHEGSVHEPTFLMKVTVAENSAEGKGTSKKKAKHSAA 181

Query: 256 ENML-EILGFK 265
             +L  ILG +
Sbjct: 182 RAVLATILGVQ 214
>25595
          Length = 353

 Score = 28.5 bits (62), Expect = 5.9,   Method: Compositional matrix adjust.
 Identities = 15/51 (29%), Positives = 26/51 (50%)
 Frame = -3

Query: 284 VKKPGDGRKVTFFEPSPGDENGTSNKDEEFRMPYLSHQQLPAGILPMVPEV 334
           V+  GDG       P P + +G +  ++  R+P   HQ   A +LP++P +
Sbjct: 258 VQHAGDGCSKLPLPPRPSN-SGVALAEQSTRIPVYRHQVCQAWVLPILPSL 109
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|47059073|ref|NP_035710.2| thrombospondin 1 [Mus
musculus]
         (1171 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

27548                                                                  83   8e-16
12743                                                                  55   2e-07
14599                                                                  43   7e-04
34726                                                                  43   8e-04
25291                                                                  43   8e-04
28816                                                                  37   0.037
13514                                                                  36   0.12 
11992                                                                  35   0.13 
30893                                                                  35   0.14 
25748                                                                  35   0.18 
30687                                                                  34   0.29 
34993                                                                  34   0.40 
12576                                                                  32   1.3  
03773                                                                  32   1.3  
18708                                                                  31   2.6  
29465                                                                  31   3.2  
33567                                                                  31   3.3  
11667                                                                  30   3.9  
18580                                                                  30   4.0  
21296                                                                  30   6.3  
14371                                                                  30   6.5  
>27548
          Length = 474

 Score = 82.8 bits (203), Expect = 8e-16,   Method: Compositional matrix adjust.
 Identities = 53/114 (46%), Positives = 63/114 (55%), Gaps = 10/114 (8%)
 Frame = -1

Query: 448 CSVTCGDG--VITRIRLCNSPSPQMNGKPCEGEARET--KACKKDACPINGGWGPW--SP 501
           CS+ CG G   +T  R C  P P   G  CEG+A +T  +AC    CPI+GGW  +    
Sbjct: 474 CSLPCGGGRMSVTYERTCTDPVPLNGGTDCEGKAEKTEEQACNTQECPIDGGWTRFVVDK 295

Query: 502 WDICSVTCGGGVQRR--SRLCNNPTPQFGGKDCVGDVTENQV--CNKQDCPIDG 551
              CS TCG G Q     R C+NP PQFGG+DCVGD T   V  CN   CP+DG
Sbjct: 294 MSQCSKTCGSGSQTLIFKRSCSNPKPQFGGRDCVGDSTNKHVQRCNPDPCPVDG 133

 Score = 79.3 bits (194), Expect = 8e-15,   Method: Compositional matrix adjust.
 Identities = 54/133 (40%), Positives = 73/133 (54%), Gaps = 13/133 (9%)
 Frame = -1

Query: 414 CEGSSVQT--RTCHIQECDKRFKQDGGWSHW--SPWSSCSVTCGDGVITRI--RLCNSPS 467
           CEG + +T  + C+ QEC      DGGW+ +     S CS TCG G  T I  R C++P 
Sbjct: 387 CEGKAEKTEEQACNTQEC----PIDGGWTRFVVDKMSQCSKTCGSGSQTLIFKRSCSNPK 220

Query: 468 PQMNGKPCEGEA--RETKACKKDACPINGGWGPWSPW---DICSVTCGGGV--QRRSRLC 520
           PQ  G+ C G++  +  + C  D CP++G W  ++ W   D CS  CG G   Q RSR C
Sbjct: 219 PQFGGRDCVGDSTNKHVQRCNPDPCPVDGQWSDFTEWEDYDECSALCGEGSKDQWRSRTC 40

Query: 521 NNPTPQFGGKDCV 533
           +NP P +GG  CV
Sbjct: 39  DNPAPAYGGSVCV 1

 Score = 37.4 bits (85), Expect = 0.039,   Method: Compositional matrix adjust.
 Identities = 36/111 (32%), Positives = 51/111 (45%), Gaps = 15/111 (13%)
 Frame = -1

Query: 380 DDGWSPW--SEWTSCSATCGNGIQQR--GRSCDSLNNR-----CEGSSVQTRTCHIQECD 430
           D GW+ +   + + CS TCG+G Q     RSC +   +     C G S      H+Q C+
Sbjct: 327 DGGWTRFVVDKMSQCSKTCGSGSQTLIFKRSCSNPKPQFGGRDCVGDSTNK---HVQRCN 157

Query: 431 KR-FKQDGGWSHWSPWS---SCSVTCGDGVIT--RIRLCNSPSPQMNGKPC 475
                 DG WS ++ W     CS  CG+G     R R C++P+P   G  C
Sbjct: 156 PDPCPVDGQWSDFTEWEDYDECSALCGEGSKDQWRSRTCDNPAPAYGGSVC 4
>12743
          Length = 528

 Score = 54.7 bits (130), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 25/48 (52%), Positives = 28/48 (58%), Gaps = 2/48 (4%)
 Frame = +2

Query: 490 CPINGGWGPWSPWDICSVTCG--GGVQRRSRLCNNPTPQFGGKDCVGD 535
           CP NG W PWS W  CS +C     +Q R R C  P P+FGG DC GD
Sbjct: 41  CPRNGSWCPWSEWSACSSSCAEETSLQVRQRTCTCPEPRFGGNDCEGD 184

 Score = 42.4 bits (98), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 20/58 (34%), Positives = 31/58 (53%), Gaps = 2/58 (3%)
 Frame = +2

Query: 430 DKRFKQDGGWSHWSPWSSCSVTCGD--GVITRIRLCNSPSPQMNGKPCEGEARETKAC 485
           D+   ++G W  WS WS+CS +C +   +  R R C  P P+  G  CEG++   + C
Sbjct: 32  DQDCPRNGSWCPWSEWSACSSSCAEETSLQVRQRTCTCPEPRFGGNDCEGDSLGVRDC 205

 Score = 36.6 bits (83), Expect = 0.055,   Method: Compositional matrix adjust.
 Identities = 20/49 (40%), Positives = 27/49 (55%), Gaps = 7/49 (14%)
 Frame = +2

Query: 383 WSPWSEWTSCSATCG--NGIQQRGRSCDSLN-----NRCEGSSVQTRTC 424
           W PWSEW++CS++C     +Q R R+C         N CEG S+  R C
Sbjct: 59  WCPWSEWSACSSSCAEETSLQVRQRTCTCPEPRFGGNDCEGDSLGVRDC 205
>14599
          Length = 1135

 Score = 43.1 bits (100), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 28/69 (40%), Positives = 35/69 (50%), Gaps = 6/69 (8%)
 Frame = -2

Query: 554 SNPCFAGAKCTSYPDGSWKCGACPPGYSGNGIQCKDVDECK------EVPDACFNHNGEH 607
           S  C A A C    D S++C  C PGY GNG  C+D+DEC       +    CFN  G  
Sbjct: 315 SQTCHAHADCVP-SDQSFQC-VCRPGYQGNGFDCQDIDECAIEVGVCDEXARCFNVYGSF 142

Query: 608 RCKNTDPGY 616
           +C+   PGY
Sbjct: 141 QCQCM-PGY 118

 Score = 40.8 bits (94), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 26/73 (35%), Positives = 38/73 (52%), Gaps = 1/73 (1%)
 Frame = -2

Query: 635 VEHAMANK-QVCKPRNPCTDGTHDCNKNAKCNYLGHYSDPMYRCECKPGYAGNGIICGED 693
           V +AM+N+  V    +PC + +  C+ +A C      SD  ++C C+PGY GNG  C   
Sbjct: 378 VRYAMSNRVSVMTGTDPCAEASQTCHAHADCVP----SDQSFQCVCRPGYQGNGFDC--- 220

Query: 694 TDLDGWPNENLVC 706
            D+D    E  VC
Sbjct: 219 QDIDECAIEVGVC 181

 Score = 32.0 bits (71), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 34/123 (27%), Positives = 50/123 (40%), Gaps = 3/123 (2%)
 Frame = -2

Query: 591 DECKEVPDACFNHNGEHRCKNTDPGYNCLPCPPRFTGSQPFGRGVEHAMANKQVCKPRNP 650
           D C E    C  H     C  +D  + C+ C P + G             N   C+  + 
Sbjct: 333 DPCAEASQTCHAHAD---CVPSDQSFQCV-CRPGYQG-------------NGFDCQDIDE 205

Query: 651 CTDGTHDCNKNAKC-NYLGHYSDPMYRCECKPGYAGNGIICG-EDTDLDG-WPNENLVCV 707
           C      C++ A+C N  G +     +C+C PGY G+G  C  E T   G +  +N  CV
Sbjct: 204 CAIEVGVCDEXARCFNVYGSF-----QCQCMPGYQGDGRTCTREQTGCGGXYCGDNARCV 40

Query: 708 ANA 710
            N+
Sbjct: 39  FNS 31
>34726
          Length = 626

 Score = 42.7 bits (99), Expect = 8e-04,   Method: Compositional matrix adjust.
 Identities = 29/73 (39%), Positives = 41/73 (56%), Gaps = 3/73 (4%)
 Frame = -1

Query: 549 IDGCLSNPCFAGAKCTSYPDGSWKCGACPPGY---SGNGIQCKDVDECKEVPDACFNHNG 605
           +D C ++PC + A CT+  DGS+ C +CP  Y   + +  QC D+DEC E  D C     
Sbjct: 518 VDECQNSPCDSVATCTN-TDGSFVC-SCPTHYRMDTTDMTQCTDIDECAENTDNC----- 360

Query: 606 EHRCKNTDPGYNC 618
           E  C NT+ G+ C
Sbjct: 359 EQVCNNTEGGFTC 321
>25291
          Length = 1059

 Score = 42.7 bits (99), Expect = 8e-04,   Method: Compositional matrix adjust.
 Identities = 22/52 (42%), Positives = 27/52 (51%)
 Frame = +2

Query: 496 WGPWSPWDICSVTCGGGVQRRSRLCNNPTPQFGGKDCVGDVTENQVCNKQDC 547
           W  W  W  C VTCGGG + R+R C   +  + G DC G   E + CN Q C
Sbjct: 83  WSGWVTWSHCPVTCGGGTRSRTRQCTGHS--WCGGDCPGQEFETRTCNSQAC 232

 Score = 41.6 bits (96), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 23/52 (44%), Positives = 26/52 (50%)
 Frame = +2

Query: 439 WSHWSPWSSCSVTCGDGVITRIRLCNSPSPQMNGKPCEGEARETKACKKDAC 490
           WS W  WS C VTCG G  +R R C   S    G  C G+  ET+ C   AC
Sbjct: 83  WSGWVTWSHCPVTCGGGTRSRTRQCTGHS--WCGGDCPGQEFETRTCNSQAC 232

 Score = 38.1 bits (87), Expect = 0.022,   Method: Compositional matrix adjust.
 Identities = 20/50 (40%), Positives = 24/50 (48%), Gaps = 3/50 (6%)
 Frame = +2

Query: 383 WSPWSEWTSCSATCGNGIQQRGRSCDS---LNNRCEGSSVQTRTCHIQEC 429
           WS W  W+ C  TCG G + R R C         C G   +TRTC+ Q C
Sbjct: 83  WSGWVTWSHCPVTCGGGTRSRTRQCTGHSWCGGDCPGQEFETRTCNSQAC 232
>28816
          Length = 437

 Score = 37.4 bits (85), Expect = 0.037,   Method: Compositional matrix adjust.
 Identities = 40/118 (33%), Positives = 51/118 (43%), Gaps = 3/118 (2%)
 Frame = +3

Query: 569 GSWKCGACPPGYS--GNGIQCKDVDECKEVPDACFNHNGEHRCKNTDPGYNCLPCPPRFT 626
           GS+ C    P Y+   NG  C DVDEC+     C      HRC NT  G +C  CP    
Sbjct: 33  GSYNCNCTHPLYTLNRNGYSCDDVDECETGQLRC-----THRCVNTAGGAHCT-CP---- 182

Query: 627 GSQPFGRGVEHAMANKQVCKPRNPCTDGTHDCNKNAKCNYLGHYSDPMYRCEC-KPGY 683
                 RG + A  N   C+  N CT      N N  C  +   ++  + CEC KPG+
Sbjct: 183 ------RGYQLADDNT-TCQDTNECT------NSNGGCEDVCTNTEGSFECECTKPGF 317
>13514
          Length = 1135

 Score = 35.8 bits (81), Expect = 0.12,   Method: Compositional matrix adjust.
 Identities = 27/80 (33%), Positives = 37/80 (46%)
 Frame = -2

Query: 550 DGCLSNPCFAGAKCTSYPDGSWKCGACPPGYSGNGIQCKDVDECKEVPDACFNHNGEHRC 609
           D C SNPC+A A C + P        C  G+ G      D++EC+E        +G   C
Sbjct: 720 DACDSNPCYASAGCETSPINGVAICTCQKGWRGADCS-IDINECQESTTTVVCEHG-GTC 547

Query: 610 KNTDPGYNCLPCPPRFTGSQ 629
           +N +  Y C  CP  FTG +
Sbjct: 546 QNLNGSYQC-NCPTGFTGRR 490
>11992
          Length = 1209

 Score = 35.4 bits (80), Expect = 0.13,   Method: Compositional matrix adjust.
 Identities = 40/141 (28%), Positives = 60/141 (42%), Gaps = 4/141 (2%)
 Frame = +2

Query: 570 SWKC-GACPPGYSGNGI-QCKDVDECKEVPDACFNHNGEHRCKNTDPGYNCLPCPPRFTG 627
           S++C   CP G+      +C+DVDEC      C+N+    RC N D GY C  CP  +  
Sbjct: 2   SYQCVRLCPRGFVRTASGECQDVDECASNTHRCYNN---QRCVNNDGGYRC-QCPKGYR- 166

Query: 628 SQPFGRGVEHAMANKQVCKPRNPCTDGTHDCNKNAKCNYLGHYSDPMYRCECKPGY--AG 685
                RG+     +   C+ R+      H+C+           +   Y+C C  GY  A 
Sbjct: 167 ----TRGIGQPCVDINECRLRSDICQ--HNCSN----------TRGSYQCSCPKGYRLAA 298

Query: 686 NGIICGEDTDLDGWPNENLVC 706
           +G  C   TD++    E + C
Sbjct: 299 DGYSC---TDINECWEERIQC 352
>30893
          Length = 490

 Score = 35.4 bits (80), Expect = 0.14,   Method: Compositional matrix adjust.
 Identities = 33/80 (41%), Positives = 38/80 (47%), Gaps = 1/80 (1%)
 Frame = +2

Query: 549 IDGCLSNPCFAGAKCTSYPDGSWKCGACPPGYSGNGIQCK-DVDECKEVPDACFNHNGEH 607
           I+ C S PC  GA CT    G + C  C PGY   G+ C+ D+DEC   P  C N    H
Sbjct: 197 INECFSAPCQNGATCTDLI-GRYTC-TCEPGYQ--GLNCEYDIDECHNQP--CLNGGTCH 358

Query: 608 RCKNTDPGYNCLPCPPRFTG 627
              NT   Y C  CPP   G
Sbjct: 359 DLVNT---YKC-SCPPGTQG 406
>25748
          Length = 425

 Score = 35.0 bits (79), Expect = 0.18,   Method: Compositional matrix adjust.
 Identities = 21/58 (36%), Positives = 32/58 (55%), Gaps = 2/58 (3%)
 Frame = +2

Query: 563 CTSYPDGSWKCGACPPGY--SGNGIQCKDVDECKEVPDACFNHNGEHRCKNTDPGYNC 618
           C + P G ++C  C  GY  + +G+ C+DV+EC+E+   C     E  C NT+  Y C
Sbjct: 158 CVTEPGGEFRC-DCYSGYQITSDGVHCEDVNECRELNGGC-----EQDCYNTEGSYQC 313
>30687
          Length = 489

 Score = 34.3 bits (77), Expect = 0.29,   Method: Compositional matrix adjust.
 Identities = 17/31 (54%), Positives = 20/31 (64%)
 Frame = +1

Query: 376 SDSADDGWSPWSEWTSCSATCGNGIQQRGRS 406
           S SAD   S W EW+ CS TCG G Q+R R+
Sbjct: 214 SQSADCQVSSWGEWSRCSVTCGVGYQERRRT 306
>34993
          Length = 626

 Score = 33.9 bits (76), Expect = 0.40,   Method: Compositional matrix adjust.
 Identities = 38/129 (29%), Positives = 56/129 (43%), Gaps = 4/129 (3%)
 Frame = -2

Query: 569 GSWKCGACPPGYSGNGIQCKDVDECKEVPDACFNHNG--EHRCKNTDPGYNCLPCPPRFT 626
           GS++C  C  G+       +D+  C +V D C +HNG  +H+C NT  G+NC  CP    
Sbjct: 613 GSYRC-RCSMGFE----LAEDMKSCLDV-DECVSHNGGCQHKCVNTYGGFNC-ECPKG-- 461

Query: 627 GSQPFGRGVEHAMANKQVCKPRNPCTDGTHDCNKNAKCNYLGHYSDPMYRCECKPGY--A 684
                    +    + + C   + C+     C       Y GH     + C C+PGY  A
Sbjct: 460 ---------QRLHVDARTCIAVSGCSVXNGGCEHVCTDGYNGH-----FHCRCRPGYTLA 323

Query: 685 GNGIICGED 693
            +G  C ED
Sbjct: 322 QDGKSCQED 296
>12576
          Length = 1682

 Score = 32.3 bits (72), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 67/254 (26%), Positives = 92/254 (36%), Gaps = 21/254 (8%)
 Frame = -1

Query: 466  PSPQMNGKPCEGEARETKACKKDACPINGGWG-------------PWSPWDICSVTCGGG 512
            P+P  NG  C  E    K   K  C  NG  G             P     +CS T  GG
Sbjct: 1313 PNPCRNGGVCSTEVSGGKLVSKCYC-ANGYEGNTCQTLADPCKPNPCKNGGLCSTTVVGG 1137

Query: 513  VQRRSRLCNNPTPQFGGKDCVGDVTENQVCNKQDCPIDGCLSNPCFAGAKCTSYPDG--- 569
                   C   +  + GK C G               D C SNPC  G +C+S   G   
Sbjct: 1136 ALTFKCFC---SAGYDGKTCTGLN-------------DPCSSNPCRNGGRCSSVAQGGAL 1005

Query: 570  SWKCGACPPGYSGNGIQCKDVDECKEVPDACFNHNGEH--RCKNTDPGYNCLP---CPPR 624
            ++ C  C  GY+G         +C +  D C +   ++   CKN       +    C P 
Sbjct: 1004 TFSC-XCINGYTG--------XDCSQTADPCSSKPCKNGGMCKNVVQNGALVAACVCAPG 852

Query: 625  FTGSQPFGRGVEHAMANKQVCKPRNPCTDGTHDCNKNAKCNYLGHYSDPMYRCECKPGYA 684
            FTG          A  +++     NPC+  +  C   A C+     S   ++C CK GY+
Sbjct: 851  FTG----------ATCSQE----NNPCS--SRPCKNGATCSPQLTRSSATFKCXCKSGYS 720

Query: 685  GNGIICGEDTDLDG 698
            G    C +  DL G
Sbjct: 719  GE--TCDQKVDLSG 684
>03773
          Length = 1046

 Score = 32.0 bits (71), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 38/127 (29%), Positives = 50/127 (39%), Gaps = 7/127 (5%)
 Frame = +2

Query: 567 PDGSWKCGACPPGYSGNGIQCKDVDECKEVPDACFNHNGEHRCKNTDPGYNCLPCPPR-- 624
            DGS+ C  C  G++     C DVDEC                  TDP  N   C  R  
Sbjct: 710 SDGSFGC-ECKSGFNSTSGSCTDVDEC------------------TDPALN--TCSDRED 826

Query: 625 ---FTGSQPFGRGVEHAMANKQVCKPRNPCTDGT-HDCNKNAKC-NYLGHYSDPMYRCEC 679
                GS        + + N  VC   N C+D + ++C     C + +G Y     RC+C
Sbjct: 827 CVNSVGSYTCQCKSTYVLVNX-VCTDFNECSDSSLNNCTSKENCVDIIGGY-----RCDC 988

Query: 680 KPGYAGN 686
           K GYA N
Sbjct: 989 KTGYARN 1009
>18708
          Length = 481

 Score = 31.2 bits (69), Expect = 2.6,   Method: Compositional matrix adjust.
 Identities = 25/80 (31%), Positives = 40/80 (50%), Gaps = 4/80 (5%)
 Frame = -3

Query: 569 GSWKCGACPPGY--SGNGIQCKDVDECKEVPDACFNHNGEHRCKNTDPGYNC--LPCPPR 624
           GS++C  CP G+    +G  C+D+DEC+E    C   +    C NT   Y C  + CP  
Sbjct: 449 GSYRC-ECPEGWRLKRDGRSCEDIDECQEKTAYCPQQDSI--CVNTRGHYKCPVVRCPQG 279

Query: 625 FTGSQPFGRGVEHAMANKQV 644
           F  +     G +H++  K++
Sbjct: 278 FAKTA--STGPQHSIRCKRM 225
>29465
          Length = 1330

 Score = 30.8 bits (68), Expect = 3.2,   Method: Composition-based stats.
 Identities = 15/54 (27%), Positives = 23/54 (42%)
 Frame = +2

Query: 354 CPIMPCSNATVPDGECCPRCWPSDSADDGWSPWSEWTSCSATCGNGIQQRGRSC 407
           C ++   + + P  +CC    P   A   WSPW   +  +  C     +R RSC
Sbjct: 851 CGLVRPLSCSPPWRDCCSASTPRPVARTTWSPWPSLSCSTPPCPIMHWRRSRSC 1012
>33567
          Length = 334

 Score = 30.8 bits (68), Expect = 3.3,   Method: Composition-based stats.
 Identities = 17/44 (38%), Positives = 20/44 (45%), Gaps = 3/44 (6%)
 Frame = +2

Query: 357 MPCSNATVPDGECCPRCWPSDSADDGWSPWSEWTSCSA---TCG 397
           M  S +T P       CWP    D G+SP +   SC A   TCG
Sbjct: 152 MGVSPSTTPLSNALSFCWPDW*LDTGFSPTASCASCCAVFLTCG 283
>11667
          Length = 1227

 Score = 30.4 bits (67), Expect = 3.9,   Method: Compositional matrix adjust.
 Identities = 41/159 (25%), Positives = 60/159 (37%), Gaps = 12/159 (7%)
 Frame = +3

Query: 557 CFAGAKCTSYPDGSWKCGACPPGYSGNG-IQCKDVDECKEVPDACFNHNGEHRCKNTDPG 615
           C    K +   DG   C  C  G++ N  I C+D++EC   P           C NT   
Sbjct: 417 CHISCKNSCTGDGPKLCSECKDGWTHNTDIGCQDINECDTSP-----CKDTEYCTNTQGS 581

Query: 616 YNCLPCPPRFTGSQPFGRGVEHAMA-------NKQVCKPRNPCTDGTHDCNKNAKCNYLG 668
           Y C+ C     G    G G +H +            C   + C++    C+   +   + 
Sbjct: 582 YMCMSCNVACDGCT--GSGPDHCVKCSAGYYLQDGKCLDMDECSEDGQLCSDEGQ---VC 746

Query: 669 HYSDPMYRCECKPGYAGNGIIC----GEDTDLDGWPNEN 703
             +   Y+CEC+PGY   G  C     ED   DG   +N
Sbjct: 747 ENTVGSYKCECQPGYNKIGDACRPKPQEDQAGDGSAEDN 863
>18580
          Length = 460

 Score = 30.4 bits (67), Expect = 4.0,   Method: Compositional matrix adjust.
 Identities = 13/21 (61%), Positives = 14/21 (66%)
 Frame = +3

Query: 441 HWSPWSSCSVTCGDGVITRIR 461
            WS +S CSVTCG G  TR R
Sbjct: 132 EWSEYSPCSVTCGKGSKTRTR 194

 Score = 29.6 bits (65), Expect = 7.4,   Method: Compositional matrix adjust.
 Identities = 12/22 (54%), Positives = 15/22 (68%)
 Frame = +3

Query: 497 GPWSPWDICSVTCGGGVQRRSR 518
           G WS +  CSVTCG G + R+R
Sbjct: 129 GEWSEYSPCSVTCGKGSKTRTR 194

 Score = 29.3 bits (64), Expect = 8.6,   Method: Compositional matrix adjust.
 Identities = 14/30 (46%), Positives = 18/30 (60%), Gaps = 4/30 (13%)
 Frame = +3

Query: 386 WSEWTSCSATCGNGIQQRGRS----CDSLN 411
           WSE++ CS TCG G + R R+    C  LN
Sbjct: 135 WSEYSPCSVTCGKGSKTRTRTNAGVCTGLN 224
>21296
          Length = 460

 Score = 30.0 bits (66), Expect = 6.3,   Method: Compositional matrix adjust.
 Identities = 14/34 (41%), Positives = 18/34 (52%)
 Frame = +2

Query: 340 CHCQNSVTICKKVSCPIMPCSNATVPDGECCPRC 373
           C C +  T C  + CP + C NA     +CCPRC
Sbjct: 5   CECLHGETDCWPLDCPQLTCQNAVQEPXDCCPRC 106
>14371
          Length = 627

 Score = 30.0 bits (66), Expect = 6.5,   Method: Compositional matrix adjust.
 Identities = 27/97 (27%), Positives = 42/97 (43%), Gaps = 1/97 (1%)
 Frame = +3

Query: 569 GSWKCGACPPGYS-GNGIQCKDVDECKEVPDACFNHNGEHRCKNTDPGYNCLPCPPRFTG 627
           GS++C +C  GY  G+  +C D++EC++    C      H C NT   Y C  CP     
Sbjct: 129 GSYRC-SCTRGYRLGDNGRCIDINECEQPSTKC-----SHDCVNTPGSYRC-ACP----- 272

Query: 628 SQPFGRGVEHAMANKQVCKPRNPCTDGTHDCNKNAKC 664
                  V + +   + C+  N C +  H C    +C
Sbjct: 273 -------VGYRLTAGRACRDINECYERNHRCASEQEC 362
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|160298217|ref|NP_034487.2| glutathione S-transferase,
alpha 4 [Mus musculus]
         (222 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

02955                                                                  80   9e-16
06833                                                                  65   2e-11
23210                                                                  45   6e-08
35754                                                                  53   1e-07
06860                                                                  39   0.002
20497                                                                  33   0.12 
32130                                                                  32   0.20 
10621                                                                  28   3.8  
>02955
          Length = 1322

 Score = 79.7 bits (195), Expect = 9e-16,   Method: Compositional matrix adjust.
 Identities = 56/196 (28%), Positives = 93/196 (47%), Gaps = 3/196 (1%)
 Frame = +1

Query: 6   KLYYFNGRGRMESIRWLLAAAGVXXXXXXXXXXXXXXKMQKDGHLLFGQVPLVEIDGMML 65
           KLYYFN RG+ E +R L  AAGV                       +GQVP V   G   
Sbjct: 28  KLYYFNVRGKGEFLRLLFRAAGVQFEDKRIERADWGPDSDAKKATPYGQVPYVIYQGKKR 207

Query: 66  TQTRAILSYLAAKYNLYGKDLKERVRIDMYADGTQDLMMMIAVAPF--KTPKEKEESYDL 123
            Q+ A+ +Y A K+  YGK  ++  + +       DL++    A F  + P++K E    
Sbjct: 208 GQSIAMGTYFARKFGFYGKTDEDAWKQEEIMHLIDDLIVGPNRAWFLEQDPQKKAERTRE 387

Query: 124 ILSRAKTRYFPVFEKILKDHGE-AFLVGNQLSWADIQLLEAILMVEELSAPVLSDFPLLQ 182
           +      RY   FE++L ++G+  + VG+ ++ AD+ L + +  V  +    L  FPL +
Sbjct: 388 LTEVQYPRYLSSFERLLAENGDQGYSVGDSVTLADLCLHDVLETVLGVDPRALXSFPLQR 567

Query: 183 AFKTRISNIPTIKKFL 198
             +  + N+P +K++L
Sbjct: 568 KLRANVENLPALKEYL 615
>06833
          Length = 882

 Score = 65.5 bits (158), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 51/202 (25%), Positives = 95/202 (47%), Gaps = 9/202 (4%)
 Frame = +3

Query: 6   KLYYFNGRGRMESIRWLLAAAGVXXXXXXXXXXXXXXKMQKDGHLLFGQVPLVEIDGM-- 63
           KLYYF+ RG  E  R LLA AG                 + +    FGQ P +       
Sbjct: 102 KLYYFDSRGFGEVSRLLLALAGQDYQDVRFDREEWAQTYKAEA--PFGQGPFLAFTDSKT 275

Query: 64  ----MLTQTRAILSYLAAKYNLYGKDLKERVRIDMYADGTQDLMMMIA-VAPFKTPKEKE 118
                + Q+ AI  +LA ++ LYG   ++   ID      +D+++    V   +   +K 
Sbjct: 276 KKLKKIGQSSAIACFLAREFGLYGSSNQDGAVIDQVVHLYRDMVVAWQKVMLTEDADKKT 455

Query: 119 ESYDLILSRAKTRYFPVFEKILKDHGEA-FLVGNQLSWADIQLLEAILMVEELSA-PVLS 176
           E++  ++     ++F  F K+L+++ ++ F VGN ++ AD+   + I  V++++     +
Sbjct: 456 EAHKKLMEEEFPKFFGHFNKLLEENSDSPFFVGNSITLADVYXYDXIFQVKKVTGYDPCA 635

Query: 177 DFPLLQAFKTRISNIPTIKKFL 198
           + P LQ    +++ IP IK ++
Sbjct: 636 NHPSLQTLYDQVAEIPNIKAYV 701
>23210
          Length = 944

 Score = 45.1 bits (105), Expect(2) = 6e-08,   Method: Compositional matrix adjust.
 Identities = 28/83 (33%), Positives = 42/83 (50%)
 Frame = -1

Query: 53  GQVPLVEIDGMMLTQTRAILSYLAAKYNLYGKDLKERVRIDMYADGTQDLMMMIAVAPFK 112
           GQ P +E  G    Q+ AI ++LA + NLYGK   + +RID     T D+   +  A F+
Sbjct: 674 GQAPFLEYKGKRYGQSIAIANFLARENNLYGKSNLDAIRIDEVVQLTADVWAALGKAHFQ 495

Query: 113 TPKEKEESYDLILSRAKTRYFPV 135
           T ++   S      R + R+FP 
Sbjct: 494 TDEK*RPS---**RRTRKRHFPT 435

 Score = 28.1 bits (61), Expect(2) = 6e-08,   Method: Compositional matrix adjust.
 Identities = 13/22 (59%), Positives = 15/22 (68%)
 Frame = -2

Query: 6   KLYYFNGRGRMESIRWLLAAAG 27
           KLYYF+ RGR E  R +L  AG
Sbjct: 805 KLYYFDARGRAELSRLVLTLAG 740
>35754
          Length = 581

 Score = 52.8 bits (125), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 48/156 (30%), Positives = 73/156 (46%), Gaps = 8/156 (5%)
 Frame = -2

Query: 60  IDG-MMLTQTRAILSYLAAKYNLYGKDLKERVRIDMYADGTQDLMMMIAVAPFKTPKEKE 118
           IDG + LTQ+ AIL Y+A K+NL G+   E  R++M  +   D    +    +  PK   
Sbjct: 469 IDGDIKLTQSNAILRYIARKHNLMGETPLESARVEMMLENAMDFRNGVVRMVY-NPK--- 302

Query: 119 ESYDLILSRAKTRY---FPVFEKILKDHGEAFLVGNQLSWADIQLLEAI----LMVEELS 171
             Y  +L   K +       F K L D  + +  G++++ AD  + E +    LM+    
Sbjct: 301 --YTDLLEEYKPKVKETLAGFNKYLAD--KKWFAGDKVTVADFHMYELLDQHRLMI---G 143

Query: 172 APVLSDFPLLQAFKTRISNIPTIKKFLQPGSQRKPP 207
           A VL D+P L AF      +P IKK++      K P
Sbjct: 142 ADVLKDYPKLTAFMAAFEALPAIKKYMASDKFMKRP 35
>06860
          Length = 498

 Score = 38.9 bits (89), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 21/72 (29%), Positives = 43/72 (59%), Gaps = 2/72 (2%)
 Frame = +1

Query: 136 FEKILKDHGEA-FLVGNQLSWADIQLLEAILMVEELSA-PVLSDFPLLQAFKTRISNIPT 193
           F K+L+++ ++ F VGN ++ AD+   + I  V++++     ++ P LQ    +++ IP 
Sbjct: 148 FNKLLEENSDSPFFVGNSITLADVYTYDFIFQVKKVTGYDPCANHPSLQTLYDQVAEIPN 327

Query: 194 IKKFLQPGSQRK 205
           IK ++   +QRK
Sbjct: 328 IKAYV---AQRK 354
>20497
          Length = 680

 Score = 32.7 bits (73), Expect = 0.12,   Method: Compositional matrix adjust.
 Identities = 32/154 (20%), Positives = 66/154 (42%), Gaps = 11/154 (7%)
 Frame = -3

Query: 53  GQVPLVEIDGMMLTQTRAILSYLAAKY-------NLYGKDLKERVRIDMYADGTQDLMMM 105
           GQVP+VE DG ++ ++  +  YL + Y       +L   +   + R DM  +   +  + 
Sbjct: 471 GQVPVVEKDGSVVCESLIVAEYLDSAYPDPRLAFHLIPANPYRKARDDMIINDYANKFIS 292

Query: 106 IAVAPFKTPKEKEESYDLILSRAKTRYFPVFEKILKDHGEAFLVGNQLSWADIQLL---E 162
                  +  +   + D +     T      E  L +    F  G + ++ D+ +    E
Sbjct: 291 SFYKIISSGGKDIAAIDTL-----TLQLQKLENTLAERNSIFFGGEKPAFVDLMIWPWQE 127

Query: 163 AILMVEELSAPV-LSDFPLLQAFKTRISNIPTIK 195
              ++   +A + L+ FP LQ ++ ++ N+P +K
Sbjct: 126 RFSVLTHYNADITLASFPHLQKWREQMFNLPAVK 25
>32130
          Length = 459

 Score = 32.0 bits (71), Expect = 0.20,   Method: Compositional matrix adjust.
 Identities = 24/78 (30%), Positives = 35/78 (44%), Gaps = 3/78 (3%)
 Frame = -3

Query: 1   MAAKPKLYYFNGRGRMESIRWLLAAAGVXXXXXXXXXXXXXXKMQKDGHLL---FGQVPL 57
           M++KP LY +        +R  LA  GV              +  K+ +      GQVP 
Sbjct: 367 MSSKPLLYSYFRSTASWRVRIALAMKGVDYDYAPVHLVKDGGEQNKEEYKSVNPMGQVPT 188

Query: 58  VEIDGMMLTQTRAILSYL 75
           + IDG+ LTQ+  I+ YL
Sbjct: 187 LVIDGLTLTQSMPIIEYL 134
>10621
          Length = 1304

 Score = 27.7 bits (60), Expect = 3.8,   Method: Compositional matrix adjust.
 Identities = 36/153 (23%), Positives = 67/153 (43%), Gaps = 10/153 (6%)
 Frame = +2

Query: 53  GQVPLVEI-DGMMLTQTRAILSYLAAKYNLYGKDLKERVRIDMYAD-GTQDLMMMIAVAP 110
           G+VP     +G+ L+++ AI  Y+  K  L G+  +   ++  + D    +++  +    
Sbjct: 170 GKVPAFSAKNGLNLSESNAIAQYVGNK-KLQGETAEAAAQVSQWIDFADNEILPSVCTWV 346

Query: 111 FK----TPKEKEESYDLILSRAKTRYFPVFEKILKDH--GEAFLVGNQLSWADIQL-LEA 163
           F     T   K+E+      RAK +       +L D+     +LVG  ++ ADI L    
Sbjct: 347 FPCLGITQFNKQET-----ERAKAQVTKALT-VLNDYLLTRTYLVGESVTQADISLACNL 508

Query: 164 ILMVEELSAPVLSD-FPLLQAFKTRISNIPTIK 195
           I++ E++  P     F  +  + T + N P  K
Sbjct: 509 IMLYEQVMDPEFRKPFQNVNRWFTTLVNQPNFK 607
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|21313138|ref|NP_083831.1| glutathione S-transferase
kappa 1 [Mus musculus]
         (226 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

28192                                                                  67   1e-15
29316                                                                  28   2.3  
28243                                                                  28   3.3  
19960                                                                  27   6.7  
>28192
          Length = 1095

 Score = 67.0 bits (162), Expect(2) = 1e-15,   Method: Compositional matrix adjust.
 Identities = 32/83 (38%), Positives = 51/83 (61%)
 Frame = +1

Query: 111 PEMLEKVSREIWMRVWSRDEDITEYQSILAAAVKAGMSTAQAQHFLEKISTQQVKNKLIE 170
           P+  E++SRE+W RV+  D D+TE  ++  AA+K+GM+    +  L  + + +VK++L  
Sbjct: 7   PQHTEQLSRELWSRVYVXDSDVTEPANLKVAALKSGMTEDVTETALVNMGSPEVKDRLKA 186

Query: 171 NTDAACKYGAFGLPTTVAHVDGK 193
            T  A   G FG P  VAHV+G+
Sbjct: 187 TTQEAADLGCFGAPFIVAHVEGR 255

 Score = 32.3 bits (72), Expect(2) = 1e-15,   Method: Compositional matrix adjust.
 Identities = 13/23 (56%), Positives = 17/23 (73%)
 Frame = +2

Query: 197 LFGSDRLELLAYLLGEKWMGPVP 219
           L GSDR  +LA ++GE W GP+P
Sbjct: 263 LLGSDRFPVLAMVIGETWKGPLP 331
>29316
          Length = 560

 Score = 28.5 bits (62), Expect = 2.3,   Method: Compositional matrix adjust.
 Identities = 10/19 (52%), Positives = 15/19 (78%)
 Frame = +2

Query: 109 EQPEMLEKVSREIWMRVWS 127
            Q E+L KVSR+I +R+W+
Sbjct: 122 RQHELLSKVSRQIRLRIWA 178
>28243
          Length = 388

 Score = 28.1 bits (61), Expect = 3.3,   Method: Compositional matrix adjust.
 Identities = 16/45 (35%), Positives = 24/45 (53%), Gaps = 3/45 (6%)
 Frame = -2

Query: 79  VPLNIPKDFFGETVKKGS---INAMRFLTTVSMEQPEMLEKVSRE 120
            PL   ++   ET  KG    INAM   T +S+ +PE  ++ +RE
Sbjct: 225 TPLQTVREVEAETQGKGKAVFINAMPSATKISINRPEAAQQNARE 91
>19960
          Length = 1401

 Score = 26.9 bits (58), Expect = 6.7,   Method: Compositional matrix adjust.
 Identities = 26/140 (18%), Positives = 51/140 (36%), Gaps = 27/140 (19%)
 Frame = -3

Query: 19  SWLGFEVLCRYQHLWNIKLQLRPTLIAGIMKDSG-----NQPPAMVPRKGQYIFKEIPLL 73
           SW G ++      L + + QLR T +    +D        QP A   ++        P+ 
Sbjct: 934 SWRGIDITETEDFLEDQRFQLRTTGLVAEKRDDQLFAVERQPSAKADKE--------PVP 779

Query: 74  KQFFQVPLNIPKDFFGET----------------------VKKGSINAMRFLTTVSMEQP 111
           K+  +  LN   +   ++                      V+K ++N  +    V  ++P
Sbjct: 778 KRRKKTELNCYSNLTNKSKIACPRKEYPTSEGYTARTIKVVEKNAVNRRKSARNVKAQKP 599

Query: 112 EMLEKVSREIWMRVWSRDED 131
           + +E+   ++W      DED
Sbjct: 598 QTVEEDGVDLWNEANPEDED 539
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|71892412|ref|NP_001025461.1| retinol dehydrogenase 8
[Mus musculus]
         (317 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

07400                                                                  80   1e-15
35613                                                                  79   3e-15
03060                                                                  74   8e-14
05690                                                                  62   3e-10
18534                                                                  60   9e-10
36378                                                                  59   2e-09
00991                                                                  50   1e-06
30930                                                                  50   2e-06
12867                                                                  49   3e-06
03983                                                                  48   6e-06
05194                                                                  45   4e-05
18039                                                                  38   0.005
05235                                                                  32   0.49 
15518                                                                  25   1.7  
02948                                                                  28   6.1  
>07400
          Length = 1577

 Score = 80.1 bits (196), Expect = 1e-15,   Method: Compositional matrix adjust.
 Identities = 53/189 (28%), Positives = 92/189 (48%), Gaps = 4/189 (2%)
 Frame = -3

Query: 3    SQQRTVLISGCSSGIGLELALQLAHDPRQRYQVVATMRDLXXXXXXXXXXXXXXXXXXSV 62
            ++ + VLI+GC +GIG E AL+     ++   VVA   D+                   V
Sbjct: 1446 AKDKVVLITGCDTGIGHEAALEA---NKRGLTVVAGCLDV----TSSGAQRLAEKKGVHV 1288

Query: 63   VQLDVCNDESVTDCLSHI----EGGQXXXXXXXXXXXXXXXXEGLSLATMQSVFNTNFFG 118
            ++LDV +DESV + +  +    E                   E  S+ T   V +   FG
Sbjct: 1287 IRLDVSSDESVANAMKSVSKLCEAKGLWAVINNAGFNRMSPVELTSMTTFHHVADVMLFG 1108

Query: 119  AVRLVKAVLPGMKRRRQGHIVVVSSVMGLQGVMFNDVYAASKFALEGFFESLAIQLRQFN 178
             VR+ KAVLP + RR +G +V VSS  G+    ++  Y  +KF +E F +   +++++++
Sbjct: 1107 TVRVTKAVLP-LVRRAKGRVVTVSSDRGMTTPAYSSAYCIAKFGVEAFSDVXRMEMKKYD 931

Query: 179  IFISMVEPG 187
            + +S+++PG
Sbjct: 930  VSVSIIQPG 904
>35613
          Length = 977

 Score = 78.6 bits (192), Expect = 3e-15,   Method: Compositional matrix adjust.
 Identities = 60/188 (31%), Positives = 87/188 (46%), Gaps = 4/188 (2%)
 Frame = +1

Query: 4   QQRTVLISGCSSGIGLELALQLAHDPRQRYQVVATMRDLXXXXXXXXXXXXXXXXXXSVV 63
           + +TVLI+GC +G G  LA  L  D      V+AT+                     +V+
Sbjct: 82  RDKTVLITGCDTGFGHALAKSLHEDG---CHVIATV--YQPDGDGAKRLRDVSTDRMTVI 246

Query: 64  QLDVCNDESVTDCLSHIEGGQXXXXXXXXXXXXXXXXEG-LSLATMQS---VFNTNFFGA 119
            LDV +D+SV  CL H++                    G + L TM+    V N N FG 
Sbjct: 247 PLDVSSDDSVEKCLRHVKQLCEHSGLWGLVNNAGHNFVGEVELTTMRQYLMVANINIFGM 426

Query: 120 VRLVKAVLPGMKRRRQGHIVVVSSVMGLQGVMFNDVYAASKFALEGFFESLAIQLRQFNI 179
           VR  +A LP + R   G IV V+S+ G      N  Y  +K+A E F E   ++++QF +
Sbjct: 427 VRTTRAFLP-LLRHATGRIVNVTSIKGQLSTPMNAAYNITKYAGETFSEITQMEMKQFGV 603

Query: 180 FISMVEPG 187
            +S+VEPG
Sbjct: 604 KVSIVEPG 627
>03060
          Length = 1893

 Score = 73.9 bits (180), Expect = 8e-14,   Method: Compositional matrix adjust.
 Identities = 36/93 (38%), Positives = 54/93 (58%)
 Frame = -1

Query: 101  EGLSLATMQSVFNTNFFGAVRLVKAVLPGMKRRRQGHIVVVSSVMGLQGVMFNDVYAASK 160
            E  S+   Q +   N+FG V L+K +LP M+ R  GHIV +SSV G   + +   Y+ASK
Sbjct: 1392 EDTSIQVDQKLMAVNYFGHVALIKGLLPHMQARNSGHIVGISSVQGKISIPYRSAYSASK 1213

Query: 161  FALEGFFESLAIQLRQFNIFISMVEPGPVTTDF 193
             AL+ FF+ L  +L    I +S++ PG + T+ 
Sbjct: 1212 HALQAFFDCLRAELSCTKIKVSLLSPGYIKTNL 1114
>05690
          Length = 1192

 Score = 62.0 bits (149), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 50/198 (25%), Positives = 86/198 (43%), Gaps = 4/198 (2%)
 Frame = +2

Query: 1   MASQQRTVLISGCSSGIGLELALQLAHDPRQRYQVVATMRDLXXXXXXXXXXXXXXXXXX 60
           + ++ + V I+GC +G+G  LA+ L      +  V      L                  
Sbjct: 161 LPAEGKAVFITGCDAGLGHLLAIHL-----DKLGVKVFAGCLFPGGEGEQTLKAKCSQRL 325

Query: 61  SVVQLDVCNDESVTDCLS----HIEGGQXXXXXXXXXXXXXXXXEGLSLATMQSVFNTNF 116
             V LDVC+ E VT         ++G +                E +  A +  + + N+
Sbjct: 326 CTVPLDVCSLEIVTTAADTVKRELDGQELWGVVNNAGIMHIGCLEVMGQADVDKILDVNY 505

Query: 117 FGAVRLVKAVLPGMKRRRQGHIVVVSSVMGLQGVMFNDVYAASKFALEGFFESLAIQLRQ 176
            G V +++A LP ++R R G +V V+S  G+  V ++ VY ASK A+    ESL ++L+ 
Sbjct: 506 RGQVNVIRAFLPFLRRSR-GRLVNVASNTGIAPVPYHAVYCASKAAVAALTESLRLELQP 682

Query: 177 FNIFISMVEPGPVTTDFE 194
           F + +S + P    T  +
Sbjct: 683 FGVRVSTIIPSGYRTGIQ 736
>18534
          Length = 406

 Score = 60.5 bits (145), Expect = 9e-10,   Method: Compositional matrix adjust.
 Identities = 33/82 (40%), Positives = 44/82 (53%), Gaps = 3/82 (3%)
 Frame = -2

Query: 108 MQSVFNTNFFGAVRLVKAVLPGMKRRRQGHIVVVSSVMGLQGVMFNDVYAASKFALEGFF 167
           +Q+ +N N       VKA LP M R  +GHIV V SV G+ G      YAA+K+A  GF 
Sbjct: 252 IQNTYNINIISHYWTVKAFLPHMMRHNRGHIVTVGSVTGMLGTYGCSDYAATKYACIGFH 73

Query: 168 ESLAIQLRQFN---IFISMVEP 186
           ESL   L+      I +S++ P
Sbjct: 72  ESLLTDLKAHGYDQIHMSLICP 7
>36378
          Length = 552

 Score = 59.3 bits (142), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 30/70 (42%), Positives = 42/70 (60%)
 Frame = -3

Query: 104 SLATMQSVFNTNFFGAVRLVKAVLPGMKRRRQGHIVVVSSVMGLQGVMFNDVYAASKFAL 163
           SL   + +   N  G + L KAVLP M +R +GH+VV+SS+ G  G   +  Y  SK AL
Sbjct: 307 SLDVDRQMLELNVLGVLSLTKAVLPHMMQRGRGHMVVMSSIAGKCGAPMSGSYTGSKHAL 128

Query: 164 EGFFESLAIQ 173
            G+FESL ++
Sbjct: 127 HGWFESLRVE 98
>00991
          Length = 1146

 Score = 49.7 bits (117), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 35/101 (34%), Positives = 52/101 (51%), Gaps = 6/101 (5%)
 Frame = +2

Query: 106 ATMQSVFNTNFFGAVRLVKAVLPGMKRRR--QGHIVVVSSVMGLQGV--MFNDVYAASKF 161
           A  + +F+ N  G + + K     M+      GHIV+V+S+ G + +       YAASKF
Sbjct: 611 AQWKHMFDVNVLGLMMVTKEAFTLMQENNIDDGHIVLVNSMSGKRVLNQKRTHCYAASKF 790

Query: 162 ALEGFFESLAIQLRQF--NIFISMVEPGPVTTDFEGKLLAQ 200
           A+   FE L  +LR+    I IS V PG V T F  +L+ +
Sbjct: 791 AVTAIFEGLRNELRELKSKIRISQVCPGLVETQFAPRLMGE 913
>30930
          Length = 1452

 Score = 49.7 bits (117), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 46/174 (26%), Positives = 74/174 (42%), Gaps = 4/174 (2%)
 Frame = -3

Query: 1    MASQQRTVLISGCSSGIGLELALQLAHDPRQRYQVVATMRDLXXXXXXXXXXXXXXXXXX 60
            ++S  + VLI+GC  G G   A +L+      Y+V A   D                   
Sbjct: 1369 LSSTGKAVLITGCDRGFGFLSAQRLSSLG---YRVFAGCFD---ATGEGAAQLRLTSPNI 1208

Query: 61   SVVQLDVCNDESVTDCL----SHIEGGQXXXXXXXXXXXXXXXXEGLSLATMQSVFNTNF 116
             V+QLDV ND  V +        ++G                  E  SL+  Q + + N+
Sbjct: 1207 DVIQLDVTNDGQVEEARRFXDEQLQGYGLWAIVNNAGTLFGAEVEWCSLSRXQRMMDVNW 1028

Query: 117  FGAVRLVKAVLPGMKRRRQGHIVVVSSVMGLQGVMFNDVYAASKFALEGFFESL 170
             G VR+ +A LP   R  +G ++ V+S+ G   +    +Y+++KFA+ GF   L
Sbjct: 1027 LGTVRITQAFLP-YVRSVKGRVINVASLSGRVALPGYALYSSTKFAVVGFLTVL 869
>12867
          Length = 858

 Score = 48.9 bits (115), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 27/87 (31%), Positives = 45/87 (51%), Gaps = 2/87 (2%)
 Frame = -3

Query: 109 QSVFNTNFFGAVRLVKAVLPGMKRRR--QGHIVVVSSVMGLQGVMFNDVYAASKFALEGF 166
           + +F  + F  V L + V+     +   +GHI   SS+ G   V F+  Y A+K AL  +
Sbjct: 640 RDLFELDVFAVVNLSRLVVRYYLEQNGGRGHIAATSSIAGFSPVPFSATYCAAKHALNAY 461

Query: 167 FESLAIQLRQFNIFISMVEPGPVTTDF 193
             SL ++ R+ ++  ++  PGP  TDF
Sbjct: 460 LMSLKMEHRKLDV--TIFAPGPTATDF 386
>03983
          Length = 1099

 Score = 47.8 bits (112), Expect = 6e-06,   Method: Compositional matrix adjust.
 Identities = 30/69 (43%), Positives = 39/69 (56%)
 Frame = +2

Query: 107 TMQSVFNTNFFGAVRLVKAVLPGMKRRRQGHIVVVSSVMGLQGVMFNDVYAASKFALEGF 166
           TM+   N +F+     VKA LP M  + +GHI+ ++S  GL GV     Y ASKFA  GF
Sbjct: 485 TMEVNSNAHFW----TVKAFLPNMLAQNKGHIISIASSAGLFGVTGLADYCASKFAAVGF 652

Query: 167 FESLAIQLR 175
            ESL  +L 
Sbjct: 653 DESLRFELE 679
>05194
          Length = 1075

 Score = 45.1 bits (105), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 22/70 (31%), Positives = 39/70 (55%)
 Frame = +1

Query: 126 VLPGMKRRRQGHIVVVSSVMGLQGVMFNDVYAASKFALEGFFESLAIQLRQFNIFISMVE 185
           +  GM +R  GHI+ +SS  G +G     VY+ SKF +EG  +++  ++    + ++ ++
Sbjct: 10  ITAGMVKRESGHIINISSDAGRKGFPGLAVYSGSKFFVEGLSQAMRSEVADSGVKVTCIQ 189

Query: 186 PGPVTTDFEG 195
           PG V T   G
Sbjct: 190 PGDVKTPLFG 219
>18039
          Length = 486

 Score = 38.1 bits (87), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 19/45 (42%), Positives = 28/45 (62%)
 Frame = -2

Query: 142 SSVMGLQGVMFNDVYAASKFALEGFFESLAIQLRQFNIFISMVEP 186
           SS+ G  G+     Y++SKFAL G  ESL ++LR  NI +++  P
Sbjct: 485 SSMAGQLGLFGYTAYSSSKFALRGLAESLQMELRPHNIQVTLAFP 351
>05235
          Length = 944

 Score = 31.6 bits (70), Expect = 0.49,   Method: Compositional matrix adjust.
 Identities = 27/98 (27%), Positives = 39/98 (39%), Gaps = 7/98 (7%)
 Frame = -2

Query: 115 NFFGAVRLVKAVLPGMKRRRQGH---IVVVSSVMGLQGVMFNDVYAASKFALEGFFESLA 171
           NF G V    A++    +R+ G    I  + SV G   +    VY+ASK     F  SLA
Sbjct: 565 NFTGTVNTTTAIMEFWDKRKGGPGGVIANICSVTGFNSIYQVPVYSASKAXALSFTNSLA 386

Query: 172 IQLRQFNIFISMVEPG----PVTTDFEGKLLAQVSKAE 205
                  + +  + PG    P+   F   L  +   AE
Sbjct: 385 KLAHITGVTVYSINPGITHTPLVNKFNSWLDVESHVAE 272
>15518
          Length = 430

 Score = 25.0 bits (53), Expect(2) = 1.7,   Method: Compositional matrix adjust.
 Identities = 13/32 (40%), Positives = 19/32 (59%), Gaps = 1/32 (3%)
 Frame = +3

Query: 176 QFNIFISMVEPGPVTTDFEGKLLA-QVSKAEF 206
           Q  I IS V PG V T+F  +L+  Q ++A +
Sbjct: 69  QIQIRISQVSPGLVKTEFGPRLMGDQYTEAYY 164

 Score = 23.1 bits (48), Expect(2) = 1.7,   Method: Compositional matrix adjust.
 Identities = 10/23 (43%), Positives = 14/23 (60%)
 Frame = +1

Query: 155 VYAASKFALEGFFESLAIQLRQF 177
            YAA+KFA+    E L  +LR+ 
Sbjct: 1   CYAATKFAVTAICEGLRNELREL 69
>02948
          Length = 1207

 Score = 27.7 bits (60), Expect = 6.1,   Method: Compositional matrix adjust.
 Identities = 15/38 (39%), Positives = 21/38 (55%)
 Frame = -2

Query: 260  TRYLPLTALKAMDPSGSLYVKTAHRLLFRWPHLLNLGL 297
            + Y+PL AL ++D SG+  V  A R     PHL +  L
Sbjct: 1077 SHYMPLHALVSVDXSGTFAVAIAQR-----PHLSHCSL 979
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|83816907|ref|NP_001033029.1| DnaJ (Hsp40) homolog,
subfamily B, member 6 isoform a [Mus musculus]
         (365 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

02324                                                                  80   1e-15
14550                                                                  77   1e-14
13998                                                                  70   2e-12
02088                                                                  67   9e-12
26984                                                                  59   4e-09
07620                                                                  47   8e-06
22505                                                                  40   1e-05
15360                                                                  44   1e-04
20409                                                                  42   5e-04
13422                                                                  40   0.001
10680                                                                  39   0.003
18150                                                                  37   0.017
33510                                                                  33   0.19 
30723                                                                  29   3.5  
>02324
          Length = 2058

 Score = 80.1 bits (196), Expect = 1e-15,   Method: Compositional matrix adjust.
 Identities = 37/65 (56%), Positives = 53/65 (81%)
 Frame = +2

Query: 4   YYEVLGVQRHASPEDIKKAYRKQALKWHPDKNPENKEEAERKFKQVAEAYEVLSDAKKRD 63
           +YEVLGV+R A  +D+KKAYRK ALK+HPDKNP++ EEA  +F+ V +AYE+L+D ++R 
Sbjct: 107 HYEVLGVERSADNDDLKKAYRKLALKFHPDKNPDSVEEATAQFRLVQQAYEILTDPQERS 286

Query: 64  IYDKY 68
            YD++
Sbjct: 287 WYDRH 301
>14550
          Length = 1395

 Score = 76.6 bits (187), Expect = 1e-14,   Method: Compositional matrix adjust.
 Identities = 37/71 (52%), Positives = 55/71 (77%)
 Frame = -1

Query: 3    DYYEVLGVQRHASPEDIKKAYRKQALKWHPDKNPENKEEAERKFKQVAEAYEVLSDAKKR 62
            D+Y++LGV + A  + IK+AYRK A + HPDKN ++  EAE++F+ +  AYEVLSD +KR
Sbjct: 1134 DFYKILGVSKSADTKQIKRAYRKIAKELHPDKNRDDP-EAEQRFQDLGAAYEVLSDEEKR 958

Query: 63   DIYDKYGKEGL 73
             +YD++G+EGL
Sbjct: 957  KVYDRHGEEGL 925
>13998
          Length = 1075

 Score = 69.7 bits (169), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 43/113 (38%), Positives = 65/113 (57%), Gaps = 7/113 (6%)
 Frame = +1

Query: 3   DYYEVLGVQRHASPEDIKKAYRKQALKWHPDKNPEN----KEEAERKFKQVAEAYEVLSD 58
           DYY++LG+ R+A+ ++IKKAYRK+AL  HPD++  +    +++ E KFK+V EAY +LSD
Sbjct: 205 DYYKILGISRNATEDEIKKAYRKKALVHHPDRHANSSADVRKDEELKFKEVGEAYAILSD 384

Query: 59  AKKRDIYDKYGKEGLNXXXXXXXIHFDSPFEFGFTFRNPDDVFREFF---GGR 108
             K+  YD               I  +   +F     +P+ +FR FF   GGR
Sbjct: 385 GAKKTRYD-----------SGHDIQDEMQADF-----DPNQMFRSFFQFSGGR 495
>02088
          Length = 1062

 Score = 67.4 bits (163), Expect = 9e-12,   Method: Compositional matrix adjust.
 Identities = 33/72 (45%), Positives = 48/72 (66%), Gaps = 1/72 (1%)
 Frame = +3

Query: 2   VDYYEVLGVQRHASPEDIKKAYRKQALKWHPDK-NPENKEEAERKFKQVAEAYEVLSDAK 60
            D YEV+G++R A+P+++KK Y K +L  HPD+ +   KE A RKF+ + + Y VLSD  
Sbjct: 105 TDLYEVIGIRREATPQEVKKGYHKVSLAVHPDQVSAAEKETATRKFQTLGKVYTVLSDKD 284

Query: 61  KRDIYDKYGKEG 72
           KR  YD+ G+ G
Sbjct: 285 KRAXYDETGEVG 320
>26984
          Length = 1107

 Score = 58.5 bits (140), Expect = 4e-09,   Method: Compositional matrix adjust.
 Identities = 32/70 (45%), Positives = 43/70 (61%)
 Frame = -2

Query: 3   DYYEVLGVQRHASPEDIKKAYRKQALKWHPDKNPENKEEAERKFKQVAEAYEVLSDAKKR 62
           D Y +LG++  AS EDIK+ YR+QA+  HPDKN E    AE  FK +  A+E++ D  KR
Sbjct: 515 DPYSILGLRADASDEDIKRYYRRQAVLVHPDKNQEPG--AEEAFKILGHAFEMIGDPTKR 342

Query: 63  DIYDKYGKEG 72
             YD +  E 
Sbjct: 341 KEYDTHILEA 312
>07620
          Length = 1775

 Score = 47.4 bits (111), Expect = 8e-06,   Method: Compositional matrix adjust.
 Identities = 20/33 (60%), Positives = 25/33 (75%)
 Frame = +1

Query: 3   DYYEVLGVQRHASPEDIKKAYRKQALKWHPDKN 35
           DYYEVL V++  +  D+KKAYRK AL+ HPDK 
Sbjct: 100 DYYEVLDVKKDCTESDMKKAYRKLALQMHPDKT 198
>22505
          Length = 784

 Score = 40.4 bits (93), Expect(2) = 1e-05,   Method: Compositional matrix adjust.
 Identities = 19/34 (55%), Positives = 24/34 (70%)
 Frame = -1

Query: 2   VDYYEVLGVQRHASPEDIKKAYRKQALKWHPDKN 35
           +D Y +LGV   A+ + I KAYRK+ALK HPDK 
Sbjct: 655 MDLYGILGVGPEANEKQIVKAYRKKALKCHPDKT 554

 Score = 26.2 bits (56), Expect(2) = 1e-05,   Method: Compositional matrix adjust.
 Identities = 13/33 (39%), Positives = 22/33 (66%)
 Frame = -3

Query: 34  KNPENKEEAERKFKQVAEAYEVLSDAKKRDIYD 66
           +NP+N + AE  F ++++A EVL+D   +  YD
Sbjct: 560 QNPDNPKAAEL-FHELSKALEVLTDPSAKAAYD 465
>15360
          Length = 502

 Score = 43.9 bits (102), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 20/53 (37%), Positives = 35/53 (66%)
 Frame = +1

Query: 5   YEVLGVQRHASPEDIKKAYRKQALKWHPDKNPENKEEAERKFKQVAEAYEVLS 57
           + +L +   +  E +K  Y++ ALKWHP+K+ +N  EA ++F QV +AY +L+
Sbjct: 61  FNLLDIPAGSDQESLKTKYKQLALKWHPEKH-KNAAEAVKQFIQVTQAYRLLA 216
>20409
          Length = 396

 Score = 41.6 bits (96), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 26/58 (44%), Positives = 32/58 (55%), Gaps = 10/58 (17%)
 Frame = +2

Query: 60  KKRDIYDKYGKEGLN---XXXXXXXIHFDSPFE-------FGFTFRNPDDVFREFFGG 107
           KKR IYD+YGK+GL            H+   F+       F F FR P++VFREFFGG
Sbjct: 143 KKRRIYDEYGKDGLGDRAQTRTHSRHHYTHDFDDFDIMGGFPFVFRPPEEVFREFFGG 316
>13422
          Length = 930

 Score = 40.4 bits (93), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 25/71 (35%), Positives = 37/71 (52%), Gaps = 7/71 (9%)
 Frame = +1

Query: 3   DYYEVLGVQR---HASPEDIKKAYRKQALKWHPDKNPENKEEAER----KFKQVAEAYEV 55
           D+Y VLG+ +    A+ + IK+ YR++ L  HPDK        E      F  ++ AYE+
Sbjct: 337 DHYAVLGLSKLRYKATADHIKRIYRQKVLLHHPDKRRARGLHVENGENDYFLCISRAYEI 516

Query: 56  LSDAKKRDIYD 66
           L D  KR  +D
Sbjct: 517 LGDPVKRRSFD 549
>10680
          Length = 1093

 Score = 39.3 bits (90), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 22/51 (43%), Positives = 31/51 (60%), Gaps = 1/51 (1%)
 Frame = -3

Query: 58   DAKKRDIYDKYGKEGLNXXXXXXXIHFDSPFEFGFTFR-NPDDVFREFFGG 107
            D +KR +YD++G+EGL            + +  G+TF  NPD VFR+FFGG
Sbjct: 1091 DQRKRAVYDQFGEEGLKNGVPTGSGETGA-WTQGYTFHGNPDKVFRDFFGG 942
>18150
          Length = 768

 Score = 36.6 bits (83), Expect = 0.017,   Method: Compositional matrix adjust.
 Identities = 15/23 (65%), Positives = 19/23 (82%)
 Frame = +2

Query: 51  EAYEVLSDAKKRDIYDKYGKEGL 73
           EA+E+LSD  KR IYD YG++GL
Sbjct: 119 EAHEILSDKHKRTIYDTYGEKGL 187
>33510
          Length = 501

 Score = 33.1 bits (74), Expect = 0.19,   Method: Compositional matrix adjust.
 Identities = 19/63 (30%), Positives = 32/63 (50%), Gaps = 2/63 (3%)
 Frame = +3

Query: 5   YEVLGVQRHASPEDIKKAYRKQALKWHPDKNPENKEEAERK--FKQVAEAYEVLSDAKKR 62
           ++  G+    S + +KK YRK  L  HPDK  ++  EA  K  F ++ +A+    D   +
Sbjct: 264 WKPCGMHDLVSADQVKKVYRKAVLSVHPDKLHDDPHEALAKLIFMELNDAWAKFEDEGMK 443

Query: 63  DIY 65
            +Y
Sbjct: 444 SLY 452
>30723
          Length = 764

 Score = 28.9 bits (63), Expect = 3.5,   Method: Compositional matrix adjust.
 Identities = 16/44 (36%), Positives = 27/44 (61%), Gaps = 2/44 (4%)
 Frame = +3

Query: 18  DIKKAYRKQALKWHPDKNPEN--KEEAERKFKQVAEAYEVLSDA 59
           D+KK  R+Q ++WHPDK  +    + A + F++V E  + +S A
Sbjct: 465 DLKKFTRQQQVRWHPDKFLQKFIDKIAPKSFEKVMERVKEISQA 596
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|84875493|ref|NP_001034183.1| neuronal growth
regulator 1 isoform a [Mus musculus]
         (348 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

13135                                                                  80   1e-15
27666                                                                  72   4e-13
20110                                                                  65   4e-11
18345                                                                  54   9e-08
08294                                                                  45   5e-05
11855                                                                  43   2e-04
37675                                                                  40   0.001
29990                                                                  39   0.003
38127                                                                  39   0.004
17530                                                                  38   0.007
25766                                                                  32   0.019
12764                                                                  36   0.024
06028                                                                  35   0.032
36700                                                                  35   0.036
25455                                                                  35   0.045
36498                                                                  35   0.048
17678                                                                  30   1.1  
35419                                                                  30   1.3  
32888                                                                  30   1.3  
34811                                                                  30   1.4  
29932                                                                  30   1.8  
07940                                                                  29   2.8  
10921                                                                  29   3.0  
10328                                                                  29   3.6  
19356                                                                  28   4.1  
>13135
          Length = 849

 Score = 80.1 bits (196), Expect = 1e-15,   Method: Compositional matrix adjust.
 Identities = 58/179 (32%), Positives = 91/179 (50%), Gaps = 11/179 (6%)
 Frame = -1

Query: 80  SVDP-RVSISTLNKRDYSLQIQNVDVTDDGPYTCSVQTQHTPRTMQVH-LTVQVPPKIYD 137
           S DP + SI   +   + L+IQN  VTD+G YTC VQ  +       H L +   P+I D
Sbjct: 549 SYDPFKYSIDLPSPTSWRLRIQNGQVTDEGVYTCQVQLSNQNYAKAFHQLVIIQMPQISD 370

Query: 138 I--SNDMTINEGTNVTLTCLATGKPEPVISWRHISPSAKPFENGQYLD----IYGITRDQ 191
           +  S+D++ +EG ++ L C A+G+P P + W  ++    P    ++L+    I  +  + 
Sbjct: 369 LDTSSDVSKSEGQSLVLRCHASGRPTPSVKWTRMAGELLPSGGREHLESDLVIPQLKPEH 190

Query: 192 AGEYECSAENDVSFPDVKKVRVIVNFAPTIQEIKSGTVTPGRSGLIR---CEGAGVPPP 247
           AG Y+CS+ N     D + +RV VNFAP +    + TV     G ++   C   G P P
Sbjct: 189 AGIYKCSSSNSAG-SDFRNIRVTVNFAPVLS--SANTVVQQAQGYVKELVCVVKGYPTP 22

 Score = 37.7 bits (86), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 36/146 (24%), Positives = 63/146 (43%), Gaps = 6/146 (4%)
 Frame = -1

Query: 160 PEPVISWRHISPSAKPFENGQYLDIYGITRDQAGEYECSAE-NDVSFPDVKKVRVIVNFA 218
           P P  SWR         +NGQ  D         G Y C  + ++ ++       VI+   
Sbjct: 516 PSPT-SWRL------RIQNGQVTD--------EGVYTCQVQLSNQNYAKAFHQLVIIQM- 385

Query: 219 PTIQEIKSGT---VTPGRSGLIRCEGAGVPPPAFEWYK--GEKRLFNGQQGIIIQNFSTR 273
           P I ++ + +    + G+S ++RC  +G P P+ +W +  GE     G++ +        
Sbjct: 384 PQISDLDTSSDVSKSEGQSLVLRCHASGRPTPSVKWTRMAGELLPSGGREHL-------E 226

Query: 274 SILTVTNVTQEHFGNYTCVAANKLGT 299
           S L +  +  EH G Y C ++N  G+
Sbjct: 225 SDLVIPQLKPEHAGIYKCSSSNSAGS 148
>27666
          Length = 873

 Score = 72.0 bits (175), Expect = 4e-13,   Method: Compositional matrix adjust.
 Identities = 48/146 (32%), Positives = 73/146 (50%), Gaps = 10/146 (6%)
 Frame = +1

Query: 91  NKRDYSLQIQNVDVTDDGPYTCSVQTQHTPRTMQVH----LTVQVPPKIY--DISNDMTI 144
           ++  ++L I+ +   D G Y C V+ Q+     QV     LTVQVPPKI   + +  + I
Sbjct: 376 DRLTFTLVIRRLRQQDAGTYVCQVKIQNENILSQVQKIGTLTVQVPPKIRPGETTTLVEI 555

Query: 145 NEGTNVTLTCLATGKPEPVISWRHISPSAKPFENGQY----LDIYGITRDQAGEYECSAE 200
           ++  N +L C +TG P P I+W  +   A P    Q+    L + G T D  G Y C A 
Sbjct: 556 DQNQNSSLVCSSTGIPAPNITWTRLDGRALPTGYSQFRGRELPLNGATVDHMGVYRCVAN 735

Query: 201 NDVSFPDVKKVRVIVNFAPTIQEIKS 226
           N++  PD     V V  APT + +++
Sbjct: 736 NNIKPPDDHLCEVRVFHAPTARTVQN 813

 Score = 33.1 bits (74), Expect = 0.15,   Method: Compositional matrix adjust.
 Identities = 32/123 (26%), Positives = 52/123 (42%), Gaps = 7/123 (5%)
 Frame = +1

Query: 182 LDIYGITRDQAGEYECSA--ENDVSFPDVKKVRVI-VNFAPTIQEIKSGT---VTPGRSG 235
           L I  + +  AG Y C    +N+     V+K+  + V   P I+  ++ T   +   ++ 
Sbjct: 394 LVIRRLRQQDAGTYVCQVKIQNENILSQVQKIGTLTVQVPPKIRPGETTTLVEIDQNQNS 573

Query: 236 LIRCEGAGVPPPAFEWYKGEKR-LFNGQQGIIIQNFSTRSILTVTNVTQEHFGNYTCVAA 294
            + C   G+P P   W + + R L  G        F  R  L +   T +H G Y CVA 
Sbjct: 574 SLVCSSTGIPAPNITWTRLDGRALPTG-----YSQFRGRE-LPLNGATVDHMGVYRCVAN 735

Query: 295 NKL 297
           N +
Sbjct: 736 NNI 744
>20110
          Length = 820

 Score = 65.1 bits (157), Expect = 4e-11,   Method: Compositional matrix adjust.
 Identities = 50/158 (31%), Positives = 73/158 (46%), Gaps = 10/158 (6%)
 Frame = -1

Query: 72  IFAGGDKWSVDPRVSISTLNKRDYSLQIQNVDVTDDGPYTCSVQTQHTPR----TMQVHL 127
           +  G  K+ V  R+S    ++  Y L ++ +  TD G YTC+V+          T   +L
Sbjct: 739 MIGGLRKYEVQKRLS---GDRETYMLVVRRLVETDAGIYTCTVRITAVSYEEWPTKIGNL 569

Query: 128 TVQVPPKIY--DISNDMTINEGTNVTLTCLATGKPEPVISWRHISPSAKPFENGQY---- 181
           TVQVPP I   D +  + I +G N TL C A+G P P I+W        P    Q+    
Sbjct: 568 TVQVPPSIKPGDTTAVLQIEQGQNSTLVCAASGIPAPNITWTRSDGGFLPIGVAQFRSAT 389

Query: 182 LDIYGITRDQAGEYECSAENDVSFPDVKKVRVIVNFAP 219
           L +  +T    G Y C A+N++  P      V+V  AP
Sbjct: 388 LPMNNVTVRDMGVYRCVADNNIKPPAEHLAEVLVFHAP 275

 Score = 33.5 bits (75), Expect = 0.14,   Method: Compositional matrix adjust.
 Identities = 31/122 (25%), Positives = 52/122 (42%), Gaps = 6/122 (4%)
 Frame = -1

Query: 182 LDIYGITRDQAGEYECSAE-NDVSFPD--VKKVRVIVNFAPTIQEIKSGTV---TPGRSG 235
           L +  +    AG Y C+     VS+ +   K   + V   P+I+   +  V     G++ 
Sbjct: 673 LVVRRLVETDAGIYTCTVRITAVSYEEWPTKIGNLTVQVPPSIKPGDTTAVLQIEQGQNS 494

Query: 236 LIRCEGAGVPPPAFEWYKGEKRLFNGQQGIIIQNFSTRSILTVTNVTQEHFGNYTCVAAN 295
            + C  +G+P P   W + +     G   I +  F + + L + NVT    G Y CVA N
Sbjct: 493 TLVCAASGIPAPNITWTRSD----GGFLPIGVAQFRS-ATLPMNNVTVRDMGVYRCVADN 329

Query: 296 KL 297
            +
Sbjct: 328 NI 323
>18345
          Length = 461

 Score = 53.9 bits (128), Expect = 9e-08,   Method: Compositional matrix adjust.
 Identities = 40/134 (29%), Positives = 63/134 (47%), Gaps = 7/134 (5%)
 Frame = +1

Query: 96  SLQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIYDISND-MTINEGTNVTLTC 154
           +L I++V + D G Y C + TQ +       +    P  + + S D +++ EG   TL C
Sbjct: 1   NLLIRHVRLNDTGVYECRINTQPSQIKQVTLVVQVPPVVLSEGSPDRVSLKEGDTATLVC 180

Query: 155 LATGKPEPVISW-----RHISPSAKPF-ENGQYLDIYGITRDQAGEYECSAENDVSFPDV 208
             TG P P ++W     R +    +     G  L +Y +TR     YEC A+N V     
Sbjct: 181 NVTGVPSPDVTWYKRNTRQLDAQKERVGSTGPVLVMYNVTRHCDDIYECYADNGVPPAVT 360

Query: 209 KKVRVIVNFAPTIQ 222
           K +RV V++AP + 
Sbjct: 361 KAIRVTVDYAPEVH 402

 Score = 35.8 bits (81), Expect = 0.030,   Method: Compositional matrix adjust.
 Identities = 21/64 (32%), Positives = 29/64 (45%)
 Frame = +1

Query: 232 GRSGLIRCEGAGVPPPAFEWYKGEKRLFNGQQGIIIQNFSTRSILTVTNVTQEHFGNYTC 291
           G +  + C   GVP P   WYK   R  + Q+  +    ST  +L + NVT+     Y C
Sbjct: 157 GDTATLVCNVTGVPSPDVTWYKRNTRQLDAQKERV---GSTGPVLVMYNVTRHCDDIYEC 327

Query: 292 VAAN 295
            A N
Sbjct: 328 YADN 339
>08294
          Length = 1849

 Score = 44.7 bits (104), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 28/84 (33%), Positives = 44/84 (52%), Gaps = 7/84 (8%)
 Frame = +2

Query: 125 VHLTVQVPPKIYDISNDMTINEGTNVTLTCLATGKPEPVISWRH----ISPSAKP---FE 177
           +H+++   P I   SN++T+ EG +  L C+A G P P I+W      I P+A+    F+
Sbjct: 53  IHISIVEWPAITVKSNNITVFEGHSAILHCVAKGSPSPDIAWYRDSQPILPNARRYTLFK 232

Query: 178 NGQYLDIYGITRDQAGEYECSAEN 201
           NG  + I  +  +  G Y C A N
Sbjct: 233 NGT-MKIRQVFMEDNGMYACVANN 301

 Score = 38.1 bits (87), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 21/72 (29%), Positives = 32/72 (44%), Gaps = 1/72 (1%)
 Frame = +2

Query: 228 TVTPGRSGLIRCEGAGVPPPAFEWYKGEKRLF-NGQQGIIIQNFSTRSILTVTNVTQEHF 286
           TV  G S ++ C   G P P   WY+  + +  N ++  + +N      + +  V  E  
Sbjct: 107 TVFEGHSAILHCVAKGSPSPDIAWYRDSQPILPNARRYTLFKN----GTMKIRQVFMEDN 274

Query: 287 GNYTCVAANKLG 298
           G Y CVA N  G
Sbjct: 275 GMYACVANNTAG 310
>11855
          Length = 1574

 Score = 42.7 bits (99), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 40/147 (27%), Positives = 60/147 (40%), Gaps = 26/147 (17%)
 Frame = +1

Query: 83  PRVSISTLNKRDYSLQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQV----------- 131
           PR+ +S+   R   L +      D+G YTC  +T    R     + V             
Sbjct: 121 PRLRLSSTKSR---LYLDCPTSQDEGEYTCVAETPFKRRVQSTIVKVDTRHYSPDVTCMS 291

Query: 132 -------PPKIYDISNDMTINEGTNVTLTCLATGKPEPVISWRHISPSAKPFENGQY-LD 183
                  P ++Y  +      E T V L C A+G PEP I+W     ++ P  +GQ+ + 
Sbjct: 292 KRGSRGEPARVYMWTVSRLELETTTVQLFCRASGYPEPTITWYDGRNNSLPDNSGQFSIA 471

Query: 184 IYG--ITRD-----QAGEYECSAENDV 203
           + G  I RD       G Y C AEN++
Sbjct: 472 VNGDLIIRDISWSENMGVYRCVAENEL 552

 Score = 36.6 bits (83), Expect = 0.014,   Method: Compositional matrix adjust.
 Identities = 20/71 (28%), Positives = 31/71 (43%), Gaps = 1/71 (1%)
 Frame = +1

Query: 239 CEGAGVPPPAFEWYKGEKRLFNGQQGIIIQNFSTRSILTVTNVT-QEHFGNYTCVAANKL 297
           C  +G P P   WY G         G    + +    L + +++  E+ G Y CVA N+L
Sbjct: 379 CRASGYPEPTITWYDGRNNSLPDNSGQF--SIAVNGDLIIRDISWSENMGVYRCVAENEL 552

Query: 298 GTTNASLPLNP 308
           G+ +    L P
Sbjct: 553 GSHSVQAFLYP 585
>37675
          Length = 741

 Score = 40.4 bits (93), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 29/98 (29%), Positives = 44/98 (44%), Gaps = 8/98 (8%)
 Frame = +2

Query: 110 YTCSVQTQHTPRTMQVH-LTVQVPPKIYDISNDMTINEGTNVTLTCLATGKPEPVISWRH 168
           Y+C   T   P ++QVH L VQ+PP +    + +      N  + C A G P+P ISW  
Sbjct: 5   YSCEDSTD--PSSLQVHALKVQMPPVVKVSPHSLIYPARLNAKMKCHAEGVPKPTISWLF 178

Query: 169 ----ISPSAKPFE---NGQYLDIYGITRDQAGEYECSA 199
               IS   + ++     + L +Y       G Y+C A
Sbjct: 179 NNVPISEDPQHYDLESANELLVVYNAGDQDTGAYKCVA 292
>29990
          Length = 434

 Score = 38.9 bits (89), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 26/91 (28%), Positives = 38/91 (41%), Gaps = 8/91 (8%)
 Frame = +3

Query: 84  RVSISTLNK----RDYSLQIQNVDVTDDGPYTCSVQT----QHTPRTMQVHLTVQVPPKI 135
           RV IS  ++     D +L I++    D G Y C  +      H+ +    +   +V P  
Sbjct: 48  RVEISGDSRFSLLHDGTLMIEDAQDDDRGVYECIARNVAGETHSNQVELRYFGERVAPXF 227

Query: 136 YDISNDMTINEGTNVTLTCLATGKPEPVISW 166
                D+   EG  V L C A+G P P  SW
Sbjct: 228 TQRPQDIVTVEGQTVQLVCQASGHPRPTFSW 320

 Score = 33.9 bits (76), Expect = 0.093,   Method: Compositional matrix adjust.
 Identities = 29/112 (25%), Positives = 45/112 (40%), Gaps = 11/112 (9%)
 Frame = +3

Query: 158 GKPEPVISWRHISPSAKPFENGQY-------LDIYGITRDQAGEYECSAENDVSFPDVKK 210
           GKP P I W H +   +   + ++       L I     D  G YEC A N        +
Sbjct: 6   GKPVPEIVWMHNNNRVEISGDSRFSLLHDGTLMIEDAQDDDRGVYECIARNVAGETHSNQ 185

Query: 211 VRVIV---NFAPTIQEIKSGTVT-PGRSGLIRCEGAGVPPPAFEWYKGEKRL 258
           V +       AP   +     VT  G++  + C+ +G P P F W +  ++L
Sbjct: 186 VELRYFGERVAPXFTQRPQDIVTVEGQTVQLVCQASGHPRPTFSWTRNLEQL 341
>38127
          Length = 860

 Score = 38.9 bits (89), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 33/141 (23%), Positives = 58/141 (41%), Gaps = 21/141 (14%)
 Frame = -1

Query: 96  SLQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVP----PKIYDISNDMTINEGTNVT 151
           +L+IQ+      G YTC  + +     ++  ++V VP    PK+        + +  ++ 
Sbjct: 800 TLEIQHPRRNFAGMYTCVAEYEEA--GVKSSISVDVPFYAHPKVLPFDKSKNLVQDESLV 627

Query: 152 LTCLATGKPEPVISW-------------RHISPSAKPFE----NGQYLDIYGITRDQAGE 194
           + C   G P+PV+SW             R+    A  ++     G  L I  +  D AGE
Sbjct: 626 IECKVLGYPKPVVSWYMDNVEIVDGADSRYSLKPANSYDGASIEGAKLVIEEVQFDDAGE 447

Query: 195 YECSAENDVSFPDVKKVRVIV 215
           Y C +     +P     +VI+
Sbjct: 446 YTCMSNYTDKWPQFNSTQVIL 384

 Score = 31.2 bits (69), Expect = 0.62,   Method: Compositional matrix adjust.
 Identities = 32/126 (25%), Positives = 47/126 (37%), Gaps = 10/126 (7%)
 Frame = -1

Query: 178 NGQYLDIYGITRDQAGEYECSAE-NDVSFPDVKKVRVIVNFAPTIQEI-KSGTVTPGRSG 235
           N   L+I    R+ AG Y C AE  +        V V     P +    KS  +    S 
Sbjct: 809 NNGTLEIQHPRRNFAGMYTCVAEYEEAGVKSSISVDVPFYAHPKVLPFDKSKNLVQDESL 630

Query: 236 LIRCEGAGVPPPAFEWYKGEKRLFNGQQGII----IQNFSTRSI----LTVTNVTQEHFG 287
           +I C+  G P P   WY     + +G           ++   SI    L +  V  +  G
Sbjct: 629 VIECKVLGYPKPVVSWYMDNVEIVDGADSRYSLKPANSYDGASIEGAKLVIEEVQFDDAG 450

Query: 288 NYTCVA 293
            YTC++
Sbjct: 449 EYTCMS 432
>17530
          Length = 503

 Score = 37.7 bits (86), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 24/68 (35%), Positives = 33/68 (48%), Gaps = 5/68 (7%)
 Frame = +2

Query: 242 AGVPPPAFEWYKGEKRLFNGQQGIII-----QNFSTRSILTVTNVTQEHFGNYTCVAANK 296
            G PPP   W K   +L NG Q I +        STR+ ++V     +H  NYTC   N+
Sbjct: 140 GGNPPPTITWTKNGVQLINGVQQIGVGQTSTSGGSTRNTVSVVMDHSDHQANYTCFVYNQ 319

Query: 297 LGTTNASL 304
           +   N+SL
Sbjct: 320 VN-INSSL 340

 Score = 33.5 bits (75), Expect = 0.11,   Method: Compositional matrix adjust.
 Identities = 39/147 (26%), Positives = 56/147 (38%), Gaps = 22/147 (14%)
 Frame = +2

Query: 126 HLTVQVPPKIYDISNDMT---INEGTNVTLTCLAT-GKPEPVISWR----HISPSAKPFE 177
           +LTV +PP    I++D+T     EG  V  TC ++ G P P I+W      +    +   
Sbjct: 35  NLTVLLPPGPPSITSDITGDVFEEGQRVRFTCSSSGGNPPPTITWTKNGVQLINGVQQIG 214

Query: 178 NGQYLDIYGITR----------DQAGEYECSAENDVSFPDVKKVRVIVN--FAP--TIQE 223
            GQ     G TR          D    Y C   N V+        V++N  ++P  T + 
Sbjct: 215 VGQTSTSGGSTRNTVSVVMDHSDHQANYTCFVYNQVNINSSLTASVVLNVRYSPIITFEP 394

Query: 224 IKSGTVTPGRSGLIRCEGAGVPPPAFE 250
                V   R   I C+    PP  F 
Sbjct: 395 FSPYIVRLDRPANITCQVDANPPCQFR 475
>25766
          Length = 469

 Score = 31.6 bits (70), Expect(2) = 0.019,   Method: Compositional matrix adjust.
 Identities = 20/84 (23%), Positives = 33/84 (39%), Gaps = 1/84 (1%)
 Frame = +1

Query: 84  RVSISTLNKRDYSLQIQNVDVTDDGPYTCSVQTQHTPRTMQ-VHLTVQVPPKIYDISNDM 142
           R +   + + D  LQI  V   D G Y C + +     +     L +  PP +     + 
Sbjct: 28  RRAAGRVREYDGILQIPRVTAADAGRYRCVITSSEGITSEGFATLRISSPPVVSVKQRNE 207

Query: 143 TINEGTNVTLTCLATGKPEPVISW 166
               G++V   C  +G P P + W
Sbjct: 208 NRQVGSSVKFHCDVSGDPVPQVRW 279

 Score = 23.5 bits (49), Expect(2) = 0.019,   Method: Compositional matrix adjust.
 Identities = 19/55 (34%), Positives = 26/55 (47%), Gaps = 4/55 (7%)
 Frame = +3

Query: 171 PSAKPFENGQYLDIYGITRDQAGEYECSA--ENDVSFPDVKKVRV--IVNFAPTI 221
           P+     NG  L +Y I ++  G Y C+A  EN V   D   +RV  I N   +I
Sbjct: 300 PAQHQIRNG-ILTLYNIQKEDEGRYICTASSENGVD-RDYSNLRVSDIRNIGSSI 458
>12764
          Length = 1055

 Score = 35.8 bits (81), Expect = 0.024,   Method: Compositional matrix adjust.
 Identities = 22/82 (26%), Positives = 35/82 (42%), Gaps = 1/82 (1%)
 Frame = +1

Query: 123 MQVHLTVQVPPKIYDISNDMTINEGTNVTLTCLATGKPEP-VISWRHISPSAKPFENGQY 181
           M   ++VQ P  +    +     EG N+ LTC+  G P P ++ WR    +      G  
Sbjct: 199 MSPQISVQYPVTVSVTPDTQQREEGLNLDLTCITQGNPLPFLVEWRQEGENTT-LATGNT 375

Query: 182 LDIYGITRDQAGEYECSAENDV 203
           L +  ++    G Y C+  N V
Sbjct: 376 LTLTNLSLSDTGTYTCTGYNTV 441
>06028
          Length = 1358

 Score = 35.4 bits (80), Expect = 0.032,   Method: Compositional matrix adjust.
 Identities = 16/46 (34%), Positives = 26/46 (56%), Gaps = 2/46 (4%)
 Frame = +1

Query: 264 GIIIQNFSTRSI--LTVTNVTQEHFGNYTCVAANKLGTTNASLPLN 307
           G  +Q F+ R I  L + N  +EH G YTC+A+N  G   + + ++
Sbjct: 376 GPSVQTFNERGIYTLAIMNAGEEHEGTYTCLASNAFGRIESHVNID 513
>36700
          Length = 595

 Score = 35.4 bits (80), Expect = 0.036,   Method: Compositional matrix adjust.
 Identities = 26/93 (27%), Positives = 40/93 (43%), Gaps = 13/93 (13%)
 Frame = +1

Query: 97  LQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIYDISNDMTINEGTNVTLTCL- 155
           L I NVD  D+  YTC  +      +  +HL V  PP        +T+ +G +    C+ 
Sbjct: 148 LVIDNVDEQDEKTYTCKGENPAGSHSGNLHLNVTSPPIFMQHLQSLTVPQGKDAYFNCVT 327

Query: 156 --ATGK--PEPVISWRH--------ISPSAKPF 176
             A+G+  P P   +R+        +SP   PF
Sbjct: 328 RSASGEKPPNPPTWYRNGLRLDNTPLSPRQVPF 426
>25455
          Length = 444

 Score = 35.0 bits (79), Expect = 0.045,   Method: Compositional matrix adjust.
 Identities = 31/121 (25%), Positives = 54/121 (44%), Gaps = 8/121 (6%)
 Frame = +1

Query: 195 YECSAE---NDVSFPDVKKVRVIVNFAPT-IQEIKSGTVTPGRSGLIRCEGAGVPPPAFE 250
           Y C AE   + ++FP ++++RV+V  AP+ +   +   V  G +  I C    +P P   
Sbjct: 1   YRCWAESTVHHINFP-LREMRVVVQSAPSWVVAPQVTEVEVGETAEITCNATAIPDPVTN 177

Query: 251 WYKGEKRLFN-GQQGIIIQNFS---TRSILTVTNVTQEHFGNYTCVAANKLGTTNASLPL 306
           W+   + + +  +  +  Q+     T   L + NVT E      C   N+ G   A + L
Sbjct: 178 WFVNGREISDVVEHDVRFQSGRFDLTSDRLILRNVTIEGRMVVQCNVTNRYGHLWADVSL 357

Query: 307 N 307
           N
Sbjct: 358 N 360
>36498
          Length = 478

 Score = 35.0 bits (79), Expect = 0.048,   Method: Compositional matrix adjust.
 Identities = 25/85 (29%), Positives = 36/85 (42%), Gaps = 4/85 (4%)
 Frame = +3

Query: 96  SLQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQ---VPPKI-YDISNDMTINEGTNVT 151
            L+   V   D G Y C  + +       V LTV    V P++  D      + +G +V 
Sbjct: 228 GLRFDPVSEGDAGRYVCVARNERGITEENVDLTVTRTGVAPQVNIDGPGRQMLVDGQSVE 407

Query: 152 LTCLATGKPEPVISWRHISPSAKPF 176
           L+C A G   P+I WR   P+  P 
Sbjct: 408 LSCSARGLRNPLIRWRR--PTGAPL 476

 Score = 32.7 bits (73), Expect = 0.21,   Method: Compositional matrix adjust.
 Identities = 18/53 (33%), Positives = 25/53 (47%), Gaps = 1/53 (1%)
 Frame = +1

Query: 122 TMQVHLTVQVPPKI-YDISNDMTINEGTNVTLTCLATGKPEPVISWRHISPSA 173
           T+   L +Q PP +       +T   G  V + C+A G P P + WR I  SA
Sbjct: 19  TLTASLVIQGPPTVTVTPGTRITALVGDRVDIECVAEGDPTPTVFWRRIEGSA 177
>17678
          Length = 876

 Score = 30.4 bits (67), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 12/31 (38%), Positives = 20/31 (64%)
 Frame = -3

Query: 276 LTVTNVTQEHFGNYTCVAANKLGTTNASLPL 306
           L +  V++  FG+YTC A+N LG  + ++ L
Sbjct: 856 LIIMRVSELDFGSYTCEASNLLGKDSETMTL 764
>35419
          Length = 623

 Score = 30.4 bits (67), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 26/95 (27%), Positives = 38/95 (40%), Gaps = 6/95 (6%)
 Frame = -2

Query: 218 APTIQEIKSGTVTPGRSGLIRCEGAGVPPPA----FEWYKGEKRLFNGQQGII--IQNFS 271
           AP   E+ +GT          C G   P        +W K  K +   +Q +   IQ+ S
Sbjct: 559 APMDLEVNAGT-----DAKFTCSGTTDPEEVHMLKIKWMKDNKEISTVEQRMTTNIQDNS 395

Query: 272 TRSILTVTNVTQEHFGNYTCVAANKLGTTNASLPL 306
               LT++       G YTC++ N L +  AS  L
Sbjct: 394 ----LTISGTIVRDSGTYTCISTNGLDSAEASAML 302
>32888
          Length = 418

 Score = 30.0 bits (66), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 11/22 (50%), Positives = 14/22 (63%)
 Frame = -3

Query: 145 NEGTNVTLTCLATGKPEPVISW 166
           +EG  V L C A GKP P ++W
Sbjct: 239 DEGQTVRLDCRAKGKPSPKVTW 174

 Score = 28.9 bits (63), Expect = 2.9,   Method: Compositional matrix adjust.
 Identities = 17/61 (27%), Positives = 27/61 (44%), Gaps = 9/61 (14%)
 Frame = -3

Query: 232 GRSGLIRCEGAGVPPPAFEWYKGEKRLFNGQQGIIIQNFS---------TRSILTVTNVT 282
           G++  + C   G P P   WYK    + NG   + I++ S         TR  + V++ T
Sbjct: 233 GQTVRLDCRAKGKPSPKVTWYKNGHIITNGDDRVEIKSTS*PSKVWERRTRETIHVSSAT 54

Query: 283 Q 283
           Q
Sbjct: 53  Q 51
>34811
          Length = 613

 Score = 30.0 bits (66), Expect = 1.4,   Method: Compositional matrix adjust.
 Identities = 23/88 (26%), Positives = 34/88 (38%), Gaps = 12/88 (13%)
 Frame = +1

Query: 178 NGQYLDIYGITRDQAGEYECSAENDVSFPDVKKVRVI---------VNFAPTIQEI-KSG 227
           N + L    I R  AG Y C A + +  P V     +         V +AP    I K  
Sbjct: 61  NSEVLSFPQIRRADAGNYSCKASSLLKVPGVGSTETVFGQGFTTINVQYAPGAASIDKID 240

Query: 228 TVTPGRSGLIRCEGA--GVPPPAFEWYK 253
            +  G+   + C  A  G P   F+W++
Sbjct: 241 NIDVGQRLQLTCSAAPQGFPEARFKWHR 324

 Score = 29.6 bits (65), Expect = 1.9,   Method: Compositional matrix adjust.
 Identities = 11/24 (45%), Positives = 16/24 (66%)
 Frame = +3

Query: 143 TINEGTNVTLTCLATGKPEPVISW 166
           TI+    +TLTC   G+P+P+I W
Sbjct: 510 TISNTQPLTLTCRGQGRPQPIIEW 581
>29932
          Length = 748

 Score = 29.6 bits (65), Expect = 1.8,   Method: Compositional matrix adjust.
 Identities = 24/84 (28%), Positives = 34/84 (40%), Gaps = 2/84 (2%)
 Frame = +3

Query: 229 VTPGRSGLIRCEGAGVPPPAFEWYKGEKRLFNGQQGIIIQNFSTRSILTVTNVTQEHFGN 288
           V   R+  I C+     P   +W     R   G   I  Q      IL    +T    G 
Sbjct: 129 VEADRNIEIYCDVTNARPENVQWATDNNRPLPGSVHIDGQ------ILRFVAITPADAGG 290

Query: 289 YTCVAANKLGTTN--ASLPLNPPS 310
           Y+C A+NK GT +  A + + PP+
Sbjct: 291 YSCTASNKYGTNSKTAQVVVRPPT 362
>07940
          Length = 1336

 Score = 29.3 bits (64), Expect = 2.8,   Method: Compositional matrix adjust.
 Identities = 12/28 (42%), Positives = 17/28 (60%)
 Frame = -3

Query: 276  LTVTNVTQEHFGNYTCVAANKLGTTNAS 303
            L ++N+T E  G YTCV +N +G    S
Sbjct: 1331 LIISNITVEDAGWYTCVVSNAIGVEYGS 1248
>10921
          Length = 525

 Score = 28.9 bits (63), Expect = 3.0,   Method: Compositional matrix adjust.
 Identities = 25/90 (27%), Positives = 37/90 (41%), Gaps = 8/90 (8%)
 Frame = -2

Query: 177 ENGQY-------LDIYGITRDQAGEYECSAENDVSFPDVKKVRVIVNFAPTIQEIKSGTV 229
           E G Y       L I  +T +   EY C A ++  F  +  + +  N   T+Q     T 
Sbjct: 452 EGGHYIISGTYNLIIVNVTLNDQAEYTCKAGSESYFGFLTVIDLPQNL--TVQ--WETTP 285

Query: 230 TPGRSGLIRCEGA-GVPPPAFEWYKGEKRL 258
           TP  +  + C  +   PPP   W+K   RL
Sbjct: 284 TPSSTSNLSCVASRAHPPPPLSWFKNGVRL 195
>10328
          Length = 922

 Score = 28.9 bits (63), Expect = 3.6,   Method: Compositional matrix adjust.
 Identities = 12/23 (52%), Positives = 15/23 (65%)
 Frame = -1

Query: 257 RLFNGQQGIIIQNFSTRSILTVT 279
           RLF GQQ ++ Q F TR  + VT
Sbjct: 88  RLFGGQQRVVCQTFRTRGPICVT 20
>19356
          Length = 451

 Score = 28.5 bits (62), Expect = 4.1,   Method: Compositional matrix adjust.
 Identities = 26/117 (22%), Positives = 45/117 (38%), Gaps = 19/117 (16%)
 Frame = -2

Query: 118 HTPRTMQVHLT--------VQVPPKIYDISNDMTINEGTNVTLTCLATGKPEPVISWRHI 169
           +TP+   +H+         V+  P +Y++    +++  T V    +       VI W   
Sbjct: 330 NTPKRQDIHIDAPIRPPQFVKPMPGLYNLQGGQSVHLETRV----IPITDSSLVIEWFK- 166

Query: 170 SPSAKPFENG-----------QYLDIYGITRDQAGEYECSAENDVSFPDVKKVRVIV 215
             + +P  NG             LDI G+  +  G+Y C A N         VR++V
Sbjct: 165 --NGRPLNNGCRFNIVFDRGFAILDIIGVISEDTGDYFCFARNKAGQAQSNVVRLLV 1
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|94372892|ref|XP_001002285.1| PREDICTED: similar to
vacuolar protein sorting 13D (yeast) isoform 6 [Mus musculus]
         (4390 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

27329                                                                  84   1e-15
33092                                                                  81   8e-15
05915                                                                  35   0.76 
01992                                                                  34   1.4  
00698                                                                  33   1.9  
32387                                                                  33   3.0  
10060                                                                  32   5.3  
11088                                                                  31   10.0 
>27329
          Length = 406

 Score = 84.3 bits (207), Expect = 1e-15,   Method: Compositional matrix adjust.
 Identities = 51/131 (38%), Positives = 70/131 (53%), Gaps = 13/131 (9%)
 Frame = +2

Query: 2401 VFLIFDWLLLVHDFLHT-------------PSDIKKQNVTPARHRNASSESAVVPKTVKS 2447
            V  IFDWLL V +FL T                +++Q   P       ++S   P TV  
Sbjct: 2    VMCIFDWLLSVQEFLMTEPPNPFLDGDVSLSDQVQRQTSMPTDKTGCHTQS---PLTVSR 172

Query: 2448 GVVTKRSSLPVSNERHLEVKVNVTGTEFVVVEDVSCFDTNAIILKGTTVLTYKPRFVDRP 2507
            G+VTKR  L    +   E+++NV+ T+FVVVE+    DTNA+ILK T VLT+KP+  D+ 
Sbjct: 173  GIVTKRGPLAEEVKVPFELRLNVSDTQFVVVENSRSLDTNAVILKSTAVLTFKPQASDKV 352

Query: 2508 FSGSLFGIEVF 2518
               SL  +EVF
Sbjct: 353  LRCSLGSLEVF 385
>33092
          Length = 457

 Score = 81.3 bits (199), Expect = 8e-15,   Method: Compositional matrix adjust.
 Identities = 43/123 (34%), Positives = 67/123 (54%)
 Frame = -3

Query: 3842 SLINKVPEELVFASLTGINIHYTQLAASHMLELSIQDVQVDNQLIGTTQPFMLYVTPLSN 3901
            SL+N  PEELV+ +L  I +  +   +   L+ S+ +V+V+NQL G  +P M+YVTP S 
Sbjct: 368  SLVNSTPEELVYVTLRNIQVEISSRHSQLTLDASVAEVKVENQLYGAVRPIMVYVTP-SL 192

Query: 3902 ENEVIETGPAVQVNAVKFPSKSALTNIYKHLMVTAQRFTVQIXXXXXXXXXSFFGYDQAE 3961
              +V +  PA+ V A K PS     +I+KHL +  +R TV +          F G  +  
Sbjct: 191  RKDVPDDTPALHVTAYKVPSAKWNADIFKHLYINTKRLTVHLEERLLWKLLQFAGLKKDR 12

Query: 3962 SEV 3964
            S++
Sbjct: 11   SDL 3
>05915
          Length = 1020

 Score = 34.7 bits (78), Expect = 0.76,   Method: Composition-based stats.
 Identities = 19/51 (37%), Positives = 27/51 (52%)
 Frame = -1

Query: 237 HYILEPVCASALLKRNCSKEPLRSRHSPRIECDIQLETIPLKLSQLQYRQI 287
           HY+L+  C + ++ R CS+  LR  H P     +Q   + L LSQL  R I
Sbjct: 348 HYVLKSGCLAGIVDRTCSQVILRQNHIP----SLQQTFLFLCLSQLHRRLI 208
>01992
          Length = 1463

 Score = 33.9 bits (76), Expect = 1.4,   Method: Composition-based stats.
 Identities = 15/29 (51%), Positives = 19/29 (65%)
 Frame = +3

Query: 1485 AFHILNNTTIQFKLEKIPIERESELTFSL 1513
            AF+I N  TIQFK+ +IP+ R     FSL
Sbjct: 819  AFYI*NQVTIQFKVLRIPVTRTGNTIFSL 905
>00698
          Length = 2225

 Score = 33.5 bits (75), Expect = 1.9,   Method: Composition-based stats.
 Identities = 15/29 (51%), Positives = 19/29 (65%)
 Frame = +3

Query: 1485 AFHILNNTTIQFKLEKIPIERESELTFSL 1513
            AF+I N  TIQFK+ +IP+ R     FSL
Sbjct: 591  AFYI*NQVTIQFKVSRIPVTRTVNTFFSL 677
>32387
          Length = 419

 Score = 32.7 bits (73), Expect = 3.0,   Method: Composition-based stats.
 Identities = 19/55 (34%), Positives = 30/55 (54%), Gaps = 4/55 (7%)
 Frame = +2

Query: 2382 HFRSTKDSSCFTVVLNNLRVFLIFDWLLLVHDFLHTPSDI----KKQNVTPARHR 2432
            H+R TK ++  T+  + L  FL   W L+ H FL T SD+     ++NV  + H+
Sbjct: 74   HWRCTKHTTPHTLGCHELNTFLW--WFLMQHTFLPTASDL**KCNEENVMNSXHQ 232
>10060
          Length = 367

 Score = 32.0 bits (71), Expect = 5.3,   Method: Composition-based stats.
 Identities = 13/26 (50%), Positives = 16/26 (61%)
 Frame = -3

Query: 1561 KFAASAPTSPCPNSPLPQLSSCGEPC 1586
            ++AASAPTS  P  P P  +SC   C
Sbjct: 230  QYAASAPTSNIPPHPSPHSASCSRTC 153
>11088
          Length = 1298

 Score = 31.2 bits (69), Expect = 10.0,   Method: Composition-based stats.
 Identities = 24/74 (32%), Positives = 33/74 (44%), Gaps = 5/74 (6%)
 Frame = +3

Query: 1700 SLAQKEYLSQSCPSVSSVEYPDMPRSLPSHMEEAPNVFQLYQRPISTCRKKPKEAQDKSY 1759
            SLA    L Q CP VS+V  P++   +  H    P +     R  + CR +P  +Q  SY
Sbjct: 675  SLATTASLLQVCPYVSTVG*PEILVLVXVHFLIPPFLCATVPRSAACCRCQPLVSQ--SY 848

Query: 1760 PQT-----PPPSPS 1768
                    P PSP+
Sbjct: 849  ASAC*SGLPVPSPA 890
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|146134422|ref|NP_035398.2| regulator of G-protein
signaling 9 [Mus musculus]
         (675 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

28964                                                                  77   2e-15
17291                                                                  55   1e-07
19559                                                                  41   0.002
24502                                                                  31   1.6  
34303                                                                  29   5.7  
>28964
          Length = 433

 Score = 77.4 bits (189), Expect(2) = 2e-15,   Method: Compositional matrix adjust.
 Identities = 42/105 (40%), Positives = 61/105 (58%), Gaps = 1/105 (0%)
 Frame = +1

Query: 318 KKEFSGENLGFWEACEDLKYG-DQSKVKEKAEEIYKLFLAPGARRWINIDGKTMDITVKG 376
           +KEFS EN+ FW A E  K+  D+   + +A EIY   L P A   +N+D     +T + 
Sbjct: 70  EKEFSEENIVFWTAVESYKHIIDEDLRRRRAGEIYSSHLGPQASDPVNVDSTARQLTEQY 249

Query: 377 LRHPHRYVLDAAQTHIYMLMKKDSYARYLKSPIYKEMLAKAIEPQ 421
           L +P   + D AQ  I+ LM+ DSY+R+LKS +YK  L + +E Q
Sbjct: 250 LDNPTPNMFDVAQHQIFQLMRTDSYSRFLKSDLYKGYLMREMEGQ 384

 Score = 23.1 bits (48), Expect(2) = 2e-15,   Method: Composition-based stats.
 Identities = 10/24 (41%), Positives = 12/24 (50%)
 Frame = +2

Query: 296 WAFNFSELIRDPKGRQSFQYFLKK 319
           WA  F  L+ D  G   F  FLK+
Sbjct: 5   WAVGFQRLLGDVAGLAIFTDFLKR 76
>17291
          Length = 479

 Score = 54.7 bits (130), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 28/62 (45%), Positives = 40/62 (64%)
 Frame = -2

Query: 382 RYVLDAAQTHIYMLMKKDSYARYLKSPIYKEMLAKAIEPQETTKRSSTLPFMRRHLRSSP 441
           R+   AAQ HI++LMKKDSYAR+L+S  YK++ A A++P E  K+       R+    +P
Sbjct: 475 RFTFLAAQEHIFLLMKKDSYARFLRSDHYKQLQANALQP-EGKKKFFNFGGSRKKNMXTP 299

Query: 442 SP 443
           SP
Sbjct: 298 SP 293
>19559
          Length = 805

 Score = 40.8 bits (94), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 37/131 (28%), Positives = 59/131 (45%), Gaps = 6/131 (4%)
 Frame = -3

Query: 295 RWAFNFSELIRDPKGRQSFQYFLKKEFSG-ENLGFWEACEDLKYGDQS---KVKEKAEEI 350
           RWA +   L+ D +G   F+ +L++E  G + L FW AC+ LK    S    V      I
Sbjct: 527 RWAKDLDYLLSDSEGVAVFRKYLEQEQGGCDELHFWFACQGLKRRADSGTVDVMNSVRVI 348

Query: 351 YKLFLAPGARRWINIDGKTMDITVKGLRHP--HRYVLDAAQTHIYMLMKKDSYARYLKSP 408
           +K ++     R I+   K  DI  K  +     + V D AQ  +   ++  SY  +L S 
Sbjct: 347 FKTYVRCDKVRSISRATK-RDIVDKLNKKSTVDQCVFDKAQXEVEAHLRHVSYLGFLNSD 171

Query: 409 IYKEMLAKAIE 419
            Y + +   +E
Sbjct: 170 EYLQYVNNYVE 138
>24502
          Length = 1135

 Score = 31.2 bits (69), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 15/40 (37%), Positives = 24/40 (60%), Gaps = 1/40 (2%)
 Frame = +3

Query: 167 RTGKERNKADRYALDCQEKAYWLVHR-SPPGMNNVLDYGL 205
           R GK R++ DRY  + ++++ WL H  S   +N V+ Y L
Sbjct: 378 RKGKGRSRTDRYVTETKKRSDWLKHLVSDLALNEVVCYAL 497
>34303
          Length = 454

 Score = 29.3 bits (64), Expect = 5.7,   Method: Composition-based stats.
 Identities = 14/33 (42%), Positives = 15/33 (45%)
 Frame = +2

Query: 519 CPSPSRVALEGSSGLEPKGEASWSGANSGPSVT 551
           CP PS  A   +S   P    SWSG   GP  T
Sbjct: 80  CPCPSTRAARANSTWPPACPTSWSGPTWGPRCT 178
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|158533976|ref|NP_848484.2| UBX domain containing 8
[Mus musculus]
         (445 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

02703                                                                  80   2e-15
01569                                                                  64   9e-11
20978                                                                  28   5.9  
>02703
          Length = 1376

 Score = 79.7 bits (195), Expect = 2e-15,   Method: Compositional matrix adjust.
 Identities = 70/298 (23%), Positives = 131/298 (43%), Gaps = 25/298 (8%)
 Frame = +2

Query: 138 SFMHSFEEKYGRAHPVFYQGTYSQALNDA----KRELRFLLVYLHGDDHQDSDEFCRNAL 193
           SF  SF E+YG  HPVFY G+   A+ DA      + + L +YLH D    +  FC   L
Sbjct: 20  SFHTSFAERYGEMHPVFYIGSLDDAIRDALQCRATDRKLLALYLHHDSSIQAHVFCSQLL 199

Query: 194 CAPEVISLINSRMLFWACSTNKPE-------------GYRVSQALRE-NTYPFLAMIMLK 239
           C+  +I+ ++S  + WA     P+             G   +  +R   T    A++++ 
Sbjct: 200 CSESIINFLSSNFITWAWDLTHPDNMDRLITSATRHFGSLAANQIRSYRTEQLPALLIIS 379

Query: 240 DRRMT--VVGRLEGLIQPDDLINQLTFIMDANQTYLVSERLEREERNQTQVLRQQQDEAY 297
             + T  V+  ++G +  ++L+ +L   ++       ++  E  ER+  ++++Q+QD+AY
Sbjct: 380 RSKATNEVLDAIQGHVTLNELMTRLLHAVEVFTHQKEADVAEERERSAREMIKQEQDQAY 559

Query: 298 LASLRADQXXXXXXXXXXXXXXXXXXXVQQQKLAEERRRQNLQEEKERKLECLXXX---- 353
             SL AD+                   +   +  EER++Q  +  KE     +       
Sbjct: 560 QESLIADRKKAEAAREEEERLRQEQEKLIALQQEEERKKQEEEAVKEAIKNSIAKSVPEE 739

Query: 354 -XXXXXXXXVKIIFKLPNDSRVERRFHFSQSLTVIHDFLFSLKESPEKFQIEANFPRR 410
                     ++ F++P   +V RRF  S +L  + ++L       E++++   +PRR
Sbjct: 740 PAPNASGDISRLRFRVPGGEQVTRRFWASNTLQDVLNYLTGQGFHTEEYKVLTTYPRR 913
>01569
          Length = 1640

 Score = 64.3 bits (155), Expect = 9e-11,   Method: Compositional matrix adjust.
 Identities = 29/84 (34%), Positives = 43/84 (51%), Gaps = 4/84 (4%)
 Frame = -1

Query: 139 FMHSFEEKYGRAHPVFYQGTYSQALNDA----KRELRFLLVYLHGDDHQDSDEFCRNALC 194
           F H F E+YG  HPVFY G+   A+ DA      + + L +YLH D    +  FC   LC
Sbjct: 827 FSHEFAERYGEMHPVFYIGSLDDAIRDALQCRATDRKLLALYLHHDSSIQAHVFCSQLLC 648

Query: 195 APEVISLINSRMLFWACSTNKPEG 218
           +  +I+ ++S  + WA     P+ 
Sbjct: 647 SESIINFLSSNFITWAWDLTHPDN 576
>20978
          Length = 378

 Score = 28.5 bits (62), Expect = 5.9,   Method: Composition-based stats.
 Identities = 14/33 (42%), Positives = 21/33 (63%)
 Frame = +3

Query: 196 PEVISLINSRMLFWACSTNKPEGYRVSQALREN 228
           PE I+LIN+ ML + C  +KP G +++  L  N
Sbjct: 222 PENINLINN*MLIFICLIHKPVGTQLNLDLAYN 320
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|23956166|ref|NP_080589.1| cisplatin
resistance-associated overexpressed protein [Mus musculus]
         (491 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

08435                                                                  80   2e-15
20660                                                                  54   2e-07
13854                                                                  30   2.4  
17716                                                                  30   2.7  
>08435
          Length = 1958

 Score = 80.1 bits (196), Expect = 2e-15,   Method: Compositional matrix adjust.
 Identities = 38/65 (58%), Positives = 48/65 (73%)
 Frame = -3

Query: 160  KLVEQLKEERELLRSTTSTIESFAAQEKQMEVCEVCGAFLIVGDAQSRVDDHLMGKQHMG 219
            KL +Q K+ER  L++ T   ++   Q KQMEVCEVCGAFLIV DA  R D+HLMGKQH G
Sbjct: 1956 KLCDQFKDERTQLQNNTGKDDT--PQFKQMEVCEVCGAFLIVDDAPQRQDEHLMGKQHAG 1783

Query: 220  YAKIK 224
            YA+++
Sbjct: 1782 YARVR 1768
>20660
          Length = 534

 Score = 53.5 bits (127), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 26/84 (30%), Positives = 52/84 (61%), Gaps = 1/84 (1%)
 Frame = -3

Query: 142 QIEELGSEGKVEEAQGMMKLVEQLKEER-ELLRSTTSTIESFAAQEKQMEVCEVCGAFLI 200
           + E LG  G+VE++  +MK +++L+ ++ +      +++ +   Q++++ VCEVC A+L 
Sbjct: 472 KAEALGEAGEVEDSMELMKEIDELRGKKIKAEHEYRTSMPASTYQQQKLRVCEVCSAYLG 293

Query: 201 VGDAQSRVDDHLMGKQHMGYAKIK 224
           + D   R+ DH  GK H+G+  I+
Sbjct: 292 IHDNDIRLADHFGGKLHLGFLTIR 221
>13854
          Length = 598

 Score = 30.0 bits (66), Expect = 2.4,   Method: Compositional matrix adjust.
 Identities = 12/31 (38%), Positives = 18/31 (58%)
 Frame = -2

Query: 20  PDEKRSNVRWDHESVCKYYLCGFCPAELFTN 50
            D+ R N++  H  +  Y+L  FC A L+TN
Sbjct: 573 ADQHRKNIKHQHALI--YFLLSFCNARLYTN 487
>17716
          Length = 450

 Score = 29.6 bits (65), Expect = 2.7,   Method: Composition-based stats.
 Identities = 13/34 (38%), Positives = 20/34 (58%)
 Frame = +2

Query: 182 FAAQEKQMEVCEVCGAFLIVGDAQSRVDDHLMGK 215
           F  Q  Q  VCE+CG   I  ++++ + +H MGK
Sbjct: 341 FP*QADQWSVCELCGLQGIAANSKTNLSEHKMGK 442
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|27369694|ref|NP_766095.1| SH3 domain binding glutamic
acid-rich protein like 2 [Mus musculus]
         (107 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

32026                                                                  77   2e-15
18626                                                                  50   3e-07
24983                                                                  27   2.0  
02415                                                                  27   2.2  
00342                                                                  26   4.6  
>32026
          Length = 431

 Score = 76.6 bits (187), Expect = 2e-15,   Method: Compositional matrix adjust.
 Identities = 44/99 (44%), Positives = 61/99 (61%), Gaps = 2/99 (2%)
 Frame = +1

Query: 2   VVRVFVASCSGFVAIKKKQQDVVRFLEANKIEFEEVDIT--MSEEQRQWMYKNIPPEKKP 59
           +++VFV S  G V ++K+QQ V+  LE  +I F+ VD+     EE R++M  N    K  
Sbjct: 127 LIKVFVTSVPGNVNLRKQQQQVLDILEGLRIPFQTVDVCDPSREEDRKFMRTNSKALKPG 306

Query: 60  AQGNPLPPQIFNGDRYCGDYDSFFESKESNTVFSFLGLK 98
           A   PLPPQIFN D YCG +DSF  S E+N ++ FL L+
Sbjct: 307 AV--PLPPQIFNQDNYCGGFDSFEFSVETNQLYEFLKLE 417
>18626
          Length = 401

 Score = 49.7 bits (117), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 21/40 (52%), Positives = 28/40 (70%)
 Frame = +3

Query: 60  AQGNPLPPQIFNGDRYCGDYDSFFESKESNTVFSFLGLKP 99
           +QG P PPQ+FN D YCGDY++F  + E +T+  FL L P
Sbjct: 69  SQGIPWPPQLFNDDEYCGDYNAFDNANEIDTLEVFLKLAP 188
>24983
          Length = 433

 Score = 26.9 bits (58), Expect = 2.0,   Method: Compositional matrix adjust.
 Identities = 9/28 (32%), Positives = 17/28 (60%)
 Frame = -2

Query: 73  DRYCGDYDSFFESKESNTVFSFLGLKPR 100
           DR C D +   + +++N   +++G KPR
Sbjct: 150 DRACKDPNPIIDGRKANVNLAYIGAKPR 67
>02415
          Length = 2763

 Score = 26.9 bits (58), Expect = 2.2,   Method: Composition-based stats.
 Identities = 9/29 (31%), Positives = 17/29 (58%)
 Frame = -1

Query: 72   GDRYCGDYDSFFESKESNTVFSFLGLKPR 100
             DR C D +   + +++N   +++G KPR
Sbjct: 1764 ADRACKDPNPIIDGRKANVNLAYIGAKPR 1678
>00342
          Length = 2538

 Score = 25.8 bits (55), Expect = 4.6,   Method: Composition-based stats.
 Identities = 9/17 (52%), Positives = 14/17 (82%)
 Frame = -1

Query: 38   DITMSEEQRQWMYKNIP 54
            D+TMSE++  W YK++P
Sbjct: 1545 DLTMSEKRWWWPYKSVP 1495
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|7949027|ref|NP_058055.1| DnaJ (Hsp40) homolog,
subfamily C, member 5 [Mus musculus]
         (198 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

14550                                                                  78   2e-15
02324                                                                  75   1e-14
13998                                                                  62   2e-10
26984                                                                  60   6e-10
02088                                                                  54   4e-08
22505                                                                  36   2e-07
33510                                                                  42   1e-04
07620                                                                  42   1e-04
13422                                                                  42   1e-04
15360                                                                  42   2e-04
18150                                                                  31   0.27 
17683                                                                  28   2.0  
17270                                                                  28   2.1  
34104                                                                  27   4.3  
12417                                                                  27   4.7  
>14550
          Length = 1395

 Score = 78.2 bits (191), Expect = 2e-15,   Method: Compositional matrix adjust.
 Identities = 33/81 (40%), Positives = 54/81 (66%)
 Frame = -1

Query: 12   SGESLYHVLGLDKNATSDDIKKSYRKLALKYHPDKNPDNPEAADKFKEINNAHAILTDAT 71
             G   Y +LG+ K+A +  IK++YRK+A + HPDKN D+PEA  +F+++  A+ +L+D  
Sbjct: 1143 GGRDFYKILGVSKSADTKQIKRAYRKIAKELHPDKNRDDPEAEQRFQDLGAAYEVLSDEE 964

Query: 72   KRNIYDKYGSLGLYVAEQFGE 92
            KR +YD++G  GL   +  G+
Sbjct: 963  KRKVYDRHGEEGLKQGDMGGD 901
>02324
          Length = 2058

 Score = 75.5 bits (184), Expect = 1e-14,   Method: Compositional matrix adjust.
 Identities = 40/95 (42%), Positives = 62/95 (65%), Gaps = 7/95 (7%)
 Frame = +2

Query: 17  YHVLGLDKNATSDDIKKSYRKLALKYHPDKNPDN-PEAADKFKEINNAHAILTDATKRNI 75
           Y VLG++++A +DD+KK+YRKLALK+HPDKNPD+  EA  +F+ +  A+ ILTD  +R+ 
Sbjct: 110 YEVLGVERSADNDDLKKAYRKLALKFHPDKNPDSVEEATAQFRLVQQAYEILTDPQERSW 289

Query: 76  YDKYGSLGLYVAEQFGEE------NVNTYFVLSSW 104
           YD++    L   +  G++      N+  YF  S +
Sbjct: 290 YDRHREAILRGGQGKGDKYEDNSLNLFQYFTSSCY 394
>13998
          Length = 1075

 Score = 61.6 bits (148), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 32/68 (47%), Positives = 47/68 (69%), Gaps = 7/68 (10%)
 Frame = +1

Query: 17  YHVLGLDKNATSDDIKKSYRKLALKYHPDKNPDNPEAAD-------KFKEINNAHAILTD 69
           Y +LG+ +NAT D+IKK+YRK AL +HPD++ ++  +AD       KFKE+  A+AIL+D
Sbjct: 211 YKILGISRNATEDEIKKAYRKKALVHHPDRHANS--SADVRKDEELKFKEVGEAYAILSD 384

Query: 70  ATKRNIYD 77
             K+  YD
Sbjct: 385 GAKKTRYD 408
>26984
          Length = 1107

 Score = 60.1 bits (144), Expect = 6e-10,   Method: Compositional matrix adjust.
 Identities = 30/74 (40%), Positives = 47/74 (63%)
 Frame = -2

Query: 6   QRSLSTSGESLYHVLGLDKNATSDDIKKSYRKLALKYHPDKNPDNPEAADKFKEINNAHA 65
           +R L+  G+  Y +LGL  +A+ +DIK+ YR+ A+  HPDKN + P A + FK + +A  
Sbjct: 542 KRLLACKGKDPYSILGLRADASDEDIKRYYRRQAVLVHPDKNQE-PGAEEAFKILGHAFE 366

Query: 66  ILTDATKRNIYDKY 79
           ++ D TKR  YD +
Sbjct: 365 MIGDPTKRKEYDTH 324
>02088
          Length = 1062

 Score = 54.3 bits (129), Expect = 4e-08,   Method: Compositional matrix adjust.
 Identities = 25/70 (35%), Positives = 41/70 (58%), Gaps = 2/70 (2%)
 Frame = +3

Query: 16  LYHVLGLDKNATSDDIKKSYRKLALKYHPDK--NPDNPEAADKFKEINNAHAILTDATKR 73
           LY V+G+ + AT  ++KK Y K++L  HPD+    +   A  KF+ +   + +L+D  KR
Sbjct: 111 LYEVIGIRREATPQEVKKGYHKVSLAVHPDQVSAAEKETATRKFQTLGKVYTVLSDKDKR 290

Query: 74  NIYDKYGSLG 83
             YD+ G +G
Sbjct: 291 AXYDETGEVG 320
>22505
          Length = 784

 Score = 36.2 bits (82), Expect(2) = 2e-07,   Method: Compositional matrix adjust.
 Identities = 17/31 (54%), Positives = 20/31 (64%)
 Frame = -1

Query: 16  LYHVLGLDKNATSDDIKKSYRKLALKYHPDK 46
           LY +LG+   A    I K+YRK ALK HPDK
Sbjct: 649 LYGILGVGPEANEKQIVKAYRKKALKCHPDK 557

 Score = 35.0 bits (79), Expect(2) = 2e-07,   Method: Compositional matrix adjust.
 Identities = 15/32 (46%), Positives = 23/32 (71%)
 Frame = -3

Query: 46  KNPDNPEAADKFKEINNAHAILTDATKRNIYD 77
           +NPDNP+AA+ F E++ A  +LTD + +  YD
Sbjct: 560 QNPDNPKAAELFHELSKALEVLTDPSAKAAYD 465
>33510
          Length = 501

 Score = 42.4 bits (98), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 26/66 (39%), Positives = 37/66 (56%), Gaps = 3/66 (4%)
 Frame = +3

Query: 14  ESLYHVLGLDKNATSDDIKKSYRKLALKYHPDKNPDNP-EAADK--FKEINNAHAILTDA 70
           ES +   G+    ++D +KK YRK  L  HPDK  D+P EA  K  F E+N+A A   D 
Sbjct: 255 ESRWKPCGMHDLVSADQVKKVYRKAVLSVHPDKLHDDPHEALAKLIFMELNDAWAKFEDE 434

Query: 71  TKRNIY 76
             +++Y
Sbjct: 435 GMKSLY 452
>07620
          Length = 1775

 Score = 42.4 bits (98), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 18/31 (58%), Positives = 23/31 (74%)
 Frame = +1

Query: 17  YHVLGLDKNATSDDIKKSYRKLALKYHPDKN 47
           Y VL + K+ T  D+KK+YRKLAL+ HPDK 
Sbjct: 106 YEVLDVKKDCTESDMKKAYRKLALQMHPDKT 198
>13422
          Length = 930

 Score = 42.4 bits (98), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 30/70 (42%), Positives = 39/70 (55%), Gaps = 9/70 (12%)
 Frame = +1

Query: 17  YHVLGLDK---NATSDDIKKSYRKLALKYHPDK------NPDNPEAADKFKEINNAHAIL 67
           Y VLGL K    AT+D IK+ YR+  L +HPDK      + +N E  D F  I+ A+ IL
Sbjct: 343 YAVLGLSKLRYKATADHIKRIYRQKVLLHHPDKRRARGLHVENGE-NDYFLCISRAYEIL 519

Query: 68  TDATKRNIYD 77
            D  KR  +D
Sbjct: 520 GDPVKRRSFD 549
>15360
          Length = 502

 Score = 41.6 bits (96), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 16/59 (27%), Positives = 37/59 (62%)
 Frame = +1

Query: 9  LSTSGESLYHVLGLDKNATSDDIKKSYRKLALKYHPDKNPDNPEAADKFKEINNAHAIL 67
          +  + E+ +++L +   +  + +K  Y++LALK+HP+K+ +  EA  +F ++  A+ +L
Sbjct: 37 MGLTREAAFNLLDIPAGSDQESLKTKYKQLALKWHPEKHKNAAEAVKQFIQVTQAYRLL 213
>18150
          Length = 768

 Score = 31.2 bits (69), Expect = 0.27,   Method: Compositional matrix adjust.
 Identities = 14/22 (63%), Positives = 15/22 (68%)
 Frame = +2

Query: 63  AHAILTDATKRNIYDKYGSLGL 84
           AH IL+D  KR IYD YG  GL
Sbjct: 122 AHEILSDKHKRTIYDTYGEKGL 187
>17683
          Length = 450

 Score = 28.5 bits (62), Expect = 2.0,   Method: Compositional matrix adjust.
 Identities = 11/26 (42%), Positives = 16/26 (61%)
 Frame = +2

Query: 21  GLDKNATSDDIKKSYRKLALKYHPDK 46
           G+  N    ++KK Y+K  + YHPDK
Sbjct: 365 GVSANPEWSEVKKLYQKAVIHYHPDK 442
>17270
          Length = 1144

 Score = 28.5 bits (62), Expect = 2.1,   Method: Compositional matrix adjust.
 Identities = 13/30 (43%), Positives = 19/30 (63%), Gaps = 1/30 (3%)
 Frame = +3

Query: 18  HVLG-LDKNATSDDIKKSYRKLALKYHPDK 46
           H++G +  N    +IKK Y+K  + YHPDK
Sbjct: 294 HMMGEVSANPEWTEIKKLYQKAVIHYHPDK 383
>34104
          Length = 369

 Score = 27.3 bits (59), Expect = 4.3,   Method: Compositional matrix adjust.
 Identities = 11/18 (61%), Positives = 15/18 (83%)
 Frame = -1

Query: 71  TKRNIYDKYGSLGLYVAE 88
           T +N+YDKYGS  L++AE
Sbjct: 345 THKNLYDKYGSNILHIAE 292
>12417
          Length = 954

 Score = 26.9 bits (58), Expect = 4.7,   Method: Compositional matrix adjust.
 Identities = 11/32 (34%), Positives = 16/32 (50%)
 Frame = +2

Query: 77  DKYGSLGLYVAEQFGEENVNTYFVLSSWWAKA 108
           D YG   L +A+QFG ++      L  W  +A
Sbjct: 422 DDYGDTALSIADQFGFKSCGRXLFLFHWQQRA 517
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|7949035|ref|NP_058045.1| dimethylarginine
dimethylaminohydrolase 2 [Mus musculus]
         (244 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

11730                                                                  57   2e-15
00846                                                                  30   1.1  
>11730
          Length = 1441

 Score = 57.0 bits (136), Expect(2) = 2e-15,   Method: Compositional matrix adjust.
 Identities = 32/62 (51%), Positives = 41/62 (66%), Gaps = 1/62 (1%)
 Frame = +1

Query: 77  DTAVIQGDTALITRPWSPARRPEVDGVRKAL-QDLGLRIVEMGDENATLDGTDVLFTGRE 135
           D AV+ G  AL+TRP   +R+ EV  +R+ L QDL L + E+ D  ATLDG DVLFTG+E
Sbjct: 121 DCAVVIGGVALVTRPGHASRQGEVGEIRRVLKQDLRLVVQEVRDAKATLDGGDVLFTGKE 300

Query: 136 FF 137
             
Sbjct: 301 IL 306

 Score = 41.6 bits (96), Expect(2) = 2e-15,   Method: Compositional matrix adjust.
 Identities = 26/89 (29%), Positives = 41/89 (46%), Gaps = 2/89 (2%)
 Frame = +3

Query: 137 FVGLSKWTNHRGAEIVADTFRDFAVSTVPVSGSS--HLRGLCGMGGPRTVVAGSSEAAQK 194
           FVG+ K TN  GA+ VAD F D++VS + +S S   HL+    M G   +          
Sbjct: 303 FVGVGKRTNFLGAKAVADAFCDYSVSLLDISASDLGHLKDGFSMAGREIMAVAPGTDCAV 482

Query: 195 AVRAMAALTDHPYASLTLPDDAASDCLFL 223
            ++ M  +    Y  + L    A D +++
Sbjct: 483 LLKKMQEVASCQYKVMQLDSRRAVDMMYI 569
>00846
          Length = 4234

 Score = 29.6 bits (65), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 16/41 (39%), Positives = 21/41 (51%), Gaps = 1/41 (2%)
 Frame = -3

Query: 187 GSSEAAQKAVRAMAALTDHPYASLTLPDDAASDC-LFLRPG 226
           G    + +AV A+   T+H Y S+ LP  AA  C  FL P 
Sbjct: 803 GIXNLSSQAVAALVYPTEHGYVSINLPPAAAVPCSFFLTPA 681
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|82933625|ref|XP_903136.1| PREDICTED: breakpoint
cluster region homolog isoform 2 [Mus musculus]
         (1226 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

17558                                                                  81   2e-15
30765                                                                  74   3e-13
20879                                                                  68   2e-11
17428                                                                  63   7e-10
12558                                                                  62   1e-09
21189                                                                  54   4e-07
11641                                                                  47   3e-05
19361                                                                  47   6e-05
19079                                                                  44   3e-04
23267                                                                  35   0.26 
18372                                                                  34   0.31 
11945                                                                  32   1.1  
06222                                                                  30   4.4  
36305                                                                  30   4.6  
>17558
          Length = 671

 Score = 81.3 bits (199), Expect = 2e-15,   Method: Compositional matrix adjust.
 Identities = 52/186 (27%), Positives = 80/186 (43%), Gaps = 2/186 (1%)
 Frame = +3

Query: 995  LKRMPSRKQTGVFGVKIAVVTKRERSKVPYIVRQCVEEIERRGMEEVGIYRVSGVATDIQ 1054
            + R P   Q  +FG  +    +    ++P I++ C+  I   G+   G++RVSG   +I 
Sbjct: 21   IGRTPPVGQPKLFGGSLEEYIEATGEEIPLIIKGCIRVINLYGLHHQGVFRVSGAQVEIN 200

Query: 1055 ALKAAFDVNNKDVSVMMSEMDVNAIAGTLKLYFRELPEPLFTDEFYPNFAEGIALSDPVA 1114
              K  F+  +  +  ++   D+N+IAG LKLYFREL EPLF    +    E    +D   
Sbjct: 201  HFKNVFESGDDALVDVVDASDMNSIAGVLKLYFRELREPLFPLHLFDALVECTRENDVHR 380

Query: 1115 KESCMXXXXXXXXXXXXXXXXXXXXXXKRVAEKETVNKMSLHNLATVFGPTLL--RPSEK 1172
            +   +                        ++E    N M  +NLA  FGPTLL   P   
Sbjct: 381  RLERIKDLLATLPRSVFVVMRYLFAFLNHLSEYSDENMMDPYNLAICFGPTLLPIPPDRD 560

Query: 1173 ESKLPA 1178
            +  LP 
Sbjct: 561  QVVLPG 578
>30765
          Length = 635

 Score = 74.3 bits (181), Expect = 3e-13,   Method: Compositional matrix adjust.
 Identities = 33/93 (35%), Positives = 59/93 (63%)
 Frame = +2

Query: 1003 QTGVFGVKIAVVTKRERSKVPYIVRQCVEEIERRGMEEVGIYRVSGVATDIQALKAAFDV 1062
            +  VFG  +     ++++ VP  V +C+  +E++G+++ G+YRVSG   +IQ L+   D 
Sbjct: 266  KDAVFGSTLQAQCDKDKAPVPNFVLECIAAVEKKGLDQDGLYRVSGNLAEIQRLRYVVDK 445

Query: 1063 NNKDVSVMMSEMDVNAIAGTLKLYFRELPEPLF 1095
            ++ D ++   + D++ + G LKL+FREL EPLF
Sbjct: 446  DD-DHNLTEDQWDIHTLTGALKLFFRELKEPLF 541
>20879
          Length = 1019

 Score = 68.2 bits (165), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 36/95 (37%), Positives = 52/95 (54%)
 Frame = -2

Query: 1011 IAVVTKRERSKVPYIVRQCVEEIERRGMEEVGIYRVSGVATDIQALKAAFDVNNKDVSVM 1070
            +A     +R  +P +V  C  EIERRG+ EVGIYRV G   D + LK  F +  K  + +
Sbjct: 598  LADFAPTQRPMIPRLVVNCANEIERRGLSEVGIYRVPGSDRDSKDLKEKF-LKGKSPN-L 425

Query: 1071 MSEMDVNAIAGTLKLYFRELPEPLFTDEFYPNFAE 1105
             + +D++ + G LK + R L EPL T   +P   E
Sbjct: 424  SNIIDIHTVCGCLKDFLRNLKEPLVTFALWPQLCE 320
>17428
          Length = 623

 Score = 63.2 bits (152), Expect = 7e-10,   Method: Compositional matrix adjust.
 Identities = 42/126 (33%), Positives = 58/126 (46%)
 Frame = +1

Query: 1042 GIYRVSGVATDIQALKAAFDVNNKDVSVMMSEMDVNAIAGTLKLYFRELPEPLFTDEFYP 1101
            G++R S ++   + LKA FD    D+    +  D N +AG +K Y RELPEP+ T + YP
Sbjct: 4    GLFRFSRISFKDEKLKACFDARLVDMEEFSN--DPNTVAGVMKQYLRELPEPMLTFDLYP 177

Query: 1102 NFAEGIALSDPVAKESCMXXXXXXXXXXXXXXXXXXXXXXKRVAEKETVNKMSLHNLATV 1161
            +F     L      +S +                        +AEK  VNKM+  NLA V
Sbjct: 178  DFMRAAQLGHDQKCQS-LYTLVNRLPPSNFNNFRYLIKFLALLAEKSHVNKMTPSNLAIV 354

Query: 1162 FGPTLL 1167
             GP LL
Sbjct: 355  MGPNLL 372
>12558
          Length = 720

 Score = 62.4 bits (150), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 45/137 (32%), Positives = 65/137 (47%), Gaps = 5/137 (3%)
 Frame = -1

Query: 1042 GIYRVSGVATDIQALKAAFDVNNKDVSVMMSE-----MDVNAIAGTLKLYFRELPEPLFT 1096
            G+YR+SGV ++IQ L+ AFD   +D +  +S+      D+++I+  LK+YFRELP PL T
Sbjct: 711  GLYRLSGVTSNIQKLRVAFD---EDQAPELSDNVQYLQDIHSISSLLKMYFRELPNPLLT 541

Query: 1097 DEFYPNFAEGIALSDPVAKESCMXXXXXXXXXXXXXXXXXXXXXXKRVAEKETVNKMSLH 1156
             + Y  FA+  A+ D   +   +                        VA       M   
Sbjct: 540  YQLYTQFAD--AVKDEDNRLLRIHDVVQQLPPPHYRTLEYLVRHLACVASYGLQTGMHSK 367

Query: 1157 NLATVFGPTLLRPSEKE 1173
            NLA V+ P LLR  E E
Sbjct: 366  NLAIVWAPNLLRSKELE 316
>21189
          Length = 461

 Score = 53.9 bits (128), Expect = 4e-07,   Method: Compositional matrix adjust.
 Identities = 34/107 (31%), Positives = 50/107 (46%)
 Frame = +3

Query: 997  RMPSRKQTGVFGVKIAVVTKRERSKVPYIVRQCVEEIERRGMEEVGIYRVSGVATDIQAL 1056
            + P      VFGV   V+ +R    +P  V   +  + +   + VGI+R SGV + I  L
Sbjct: 147  KAPQFSDKNVFGVPFTVILQRTGQPLPQCVLYAMRYLRKTSHDAVGIFRKSGVRSRIHKL 326

Query: 1057 KAAFDVNNKDVSVMMSEMDVNAIAGTLKLYFRELPEPLFTDEFYPNF 1103
            +    V +   +V   E+    +A  LK YFRELPE L T +    F
Sbjct: 327  RDM--VESCPDTVNFDELQPYDVADLLKQYFRELPECLLTTKLSDTF 461
>11641
          Length = 2509

 Score = 47.4 bits (111), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 32/107 (29%), Positives = 55/107 (51%)
 Frame = -1

Query: 595  DNYGVAMETAEKCCQANAQFAEISENLRARSNKDVKDSTTKNSLETLLYKPVDRVTRSTL 654
            D+    M+   +  +A   FA   E +R R+N  + D      +E +L KPV R+ +  L
Sbjct: 2476 DDVISVMDKYHELPEACQYFAAKVEEMRRRTN--IFD------VEAMLIKPVQRILKYPL 2321

Query: 655  VLHDLLKHTPSSHPDHSLLQDALRISQNFLSSINEEITPRRQSMTVK 701
            +L++L K T   HPD + + +A+R   +  ++INE    RR+ +  K
Sbjct: 2320 LLNELFKSTEDDHPDKTAIGNAIRAMTDVATAINE--YKRRKDLVFK 2186
>19361
          Length = 685

 Score = 46.6 bits (109), Expect = 6e-05,   Method: Compositional matrix adjust.
 Identities = 21/55 (38%), Positives = 35/55 (63%), Gaps = 1/55 (1%)
 Frame = -1

Query: 998  MPSRKQTG-VFGVKIAVVTKRERSKVPYIVRQCVEEIERRGMEEVGIYRVSGVAT 1051
            MP+ K    ++GV +  VTK  +  +P +V  C++EIE+RG+E  G+YR++   T
Sbjct: 166  MPNMKYVKRLYGVDLTTVTKANKQILPIVVEXCIKEIEKRGVEPEGLYRLAXSTT 2
>19079
          Length = 436

 Score = 44.3 bits (103), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 21/55 (38%), Positives = 29/55 (52%)
 Frame = -1

Query: 1051 TDIQALKAAFDVNNKDVSVMMSEMDVNAIAGTLKLYFRELPEPLFTDEFYPNFAE 1105
             DI   KA F+     +  +    ++N++AG LKLYFREL EPLF    +    E
Sbjct: 376  VDINNFKAVFESGEDALVDVTDASEMNSVAGVLKLYFRELREPLFPLHLFDALVE 212
>23267
          Length = 1271

 Score = 34.7 bits (78), Expect = 0.26,   Method: Compositional matrix adjust.
 Identities = 18/61 (29%), Positives = 29/61 (47%)
 Frame = -3

Query: 997  RMPSRKQTGVFGVKIAVVTKRERSKVPYIVRQCVEEIERRGMEEVGIYRVSGVATDIQAL 1056
            + P      VFGV   V+ +R    +P  V   +  + +   + VGI+R SGV + I  L
Sbjct: 1125 KAPQFSDKNVFGVPFTVILQRTGQPLPQCVLYAMRYLRKTSHDAVGIFRKSGVRSRIHKL 946

Query: 1057 K 1057
            +
Sbjct: 945  R 943
>18372
          Length = 468

 Score = 34.3 bits (77), Expect = 0.31,   Method: Compositional matrix adjust.
 Identities = 28/78 (35%), Positives = 36/78 (46%), Gaps = 7/78 (8%)
 Frame = +2

Query: 618 SENLRAR---SNKDVKDSTT----KNSLETLLYKPVDRVTRSTLVLHDLLKHTPSSHPDH 670
           SE LR R   SN   KD       K  L   L KPV R+T+  L+L ++L+ T       
Sbjct: 110 SEALRMRVGDSNPFFKDCQQRLGHKLPLGAYLLKPVQRITKYQLLLKEMLRFTGEDEDLE 289

Query: 671 SLLQDALRISQNFLSSIN 688
             LQDAL    + L  +N
Sbjct: 290 RQLQDALSTMLSVLQYLN 343
>11945
          Length = 1161

 Score = 32.3 bits (72), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 26/135 (19%), Positives = 48/135 (35%)
 Frame = -1

Query: 1045 RVSGVATDIQALKAAFDVNNKDVSVMMSEMDVNAIAGTLKLYFRELPEPLFTDEFYPNFA 1104
            RV G  T ++ L+   +      +    E+  N  A  LK + RELP PL T ++   F 
Sbjct: 417  RVPGSVTRVKQLRHELEEKFYQNTFNWGEVMPNDCAALLKQFLRELPTPLLTYDYLEAFP 238

Query: 1105 EGIALSDPVAKESCMXXXXXXXXXXXXXXXXXXXXXXKRVAEKETVNKMSLHNLATVFGP 1164
            +   +   + +   +                      + +      NKM L+N+  +   
Sbjct: 237  QVENIPKTLEQLKALNLLVLLLPTEHRDVLKVLLRFLRNIVSHSDTNKMGLNNICMIMAQ 58

Query: 1165 TLLRPSEKESKLPAN 1179
             L      + K+ A+
Sbjct: 57   ILFIAPAGKGKVKAS 13
>06222
          Length = 904

 Score = 30.4 bits (67), Expect = 4.4,   Method: Composition-based stats.
 Identities = 14/38 (36%), Positives = 24/38 (63%)
 Frame = -1

Query: 670 HSLLQDALRISQNFLSSINEEITPRRQSMTVKKGEHRQ 707
           H++L DAL I QNF SS++++  P      V+ G+ ++
Sbjct: 838 HNILCDALLILQNFFSSVHKKTKPNPPIFGVEFGQWKK 725
>36305
          Length = 586

 Score = 30.4 bits (67), Expect = 4.6,   Method: Composition-based stats.
 Identities = 13/27 (48%), Positives = 17/27 (62%)
 Frame = -1

Query: 945 KTRVYRDTTEPNWNELDPQTLQDRDWQ 971
           KT+V  DT EP WNE+    + +RD Q
Sbjct: 535 KTKVIDDTVEPRWNEVFEFVIDERDGQ 455
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|9790219|ref|NP_062745.1| destrin [Mus musculus]
         (165 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

16094                                                                  77   2e-15
23740                                                                  28   1.4  
01190                                                                  27   3.1  
05305                                                                  26   8.3  
>16094
          Length = 1173

 Score = 77.4 bits (189), Expect = 2e-15,   Method: Compositional matrix adjust.
 Identities = 52/158 (32%), Positives = 86/158 (54%), Gaps = 6/158 (3%)
 Frame = +2

Query: 1   MASGVQVADEVCRIFYDMKVRKCSTPEEIKKRKKAVIFCLSADKKCIVVE------EGKE 54
           M+SG+QV+DEV +++  +K+   + P     +++  +F L+ DK  IV++      E K 
Sbjct: 125 MSSGIQVSDEVKQVYEQVKM---NGPN----KRQFALFKLNDDKTEIVLDYMADKCESKS 283

Query: 55  ILVGDVGATITDPFKHFVGMLPEKDCRYALYDASFETKESRKEELMFFLWAPEQAPLKSK 114
               + G      F+  +  LP+KD RY L+D  +E K     +L+  +W PE   +  K
Sbjct: 284 NETKEKGQA--KHFQEVINTLPKKDGRYLLFDYEYEGKHGPASKLVLIMWCPEILSVNMK 457

Query: 115 MIYASSKDAIKKKFPGIKHEYQANGPEDLNRTCIAEKL 152
           M+YASSKDA+KK    I  + QA+  +DL+ + +  KL
Sbjct: 458 MLYASSKDALKKTCKDIGADIQADCLDDLSTSDVEFKL 571
>23740
          Length = 917

 Score = 28.5 bits (62), Expect = 1.4,   Method: Compositional matrix adjust.
 Identities = 15/44 (34%), Positives = 20/44 (45%)
 Frame = -2

Query: 39  CLSADKKCIVVEEGKEILVGDVGATITDPFKHFVGMLPEKDCRY 82
           CL   K  +V++ G+      VGA    PF  FVG  P    R+
Sbjct: 493 CL*QSKHRVVIQAGQSRTPSLVGAACPFPFFLFVGSAPTPXXRW 362
>01190
          Length = 1210

 Score = 27.3 bits (59), Expect = 3.1,   Method: Compositional matrix adjust.
 Identities = 14/40 (35%), Positives = 22/40 (55%)
 Frame = +3

Query: 85  YDASFETKESRKEELMFFLWAPEQAPLKSKMIYASSKDAI 124
           YD + E KESR   L +     + APL   +++AS++  I
Sbjct: 57  YDRTVENKESRAPLLFWGT*GAKVAPLPGGLLWASAR*TI 176
>05305
          Length = 1371

 Score = 25.8 bits (55), Expect = 8.3,   Method: Compositional matrix adjust.
 Identities = 16/55 (29%), Positives = 24/55 (43%), Gaps = 9/55 (16%)
 Frame = -2

Query: 5   VQVADEVCRIFYDMKVRKCSTPEEI---------KKRKKAVIFCLSADKKCIVVE 50
           + V    CR+  + K+R+  +P  I         K RK+ +IF    D  CI V 
Sbjct: 980 IMVTHATCRVTLEWKIRRLRSPFSIASPV*PVSNKXRKERMIFMRY*DWYCISVR 816
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|14389431|ref|NP_058017.1| stress-induced
phosphoprotein 1 [Mus musculus]
         (543 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

08670                                                                  79   3e-15
30337                                                                  72   6e-13
35348                                                                  67   2e-11
01124                                                                  64   1e-10
35264                                                                  63   3e-10
04645                                                                  63   3e-10
35341                                                                  54   2e-07
23484                                                                  51   1e-06
00888                                                                  45   6e-05
13560                                                                  45   9e-05
03857                                                                  41   0.001
22027                                                                  37   0.026
32109                                                                  35   0.068
14231                                                                  31   1.0  
10994                                                                  31   1.4  
17748                                                                  31   1.6  
28154                                                                  29   4.5  
>08670
          Length = 1307

 Score = 79.3 bits (194), Expect = 3e-15,   Method: Compositional matrix adjust.
 Identities = 40/110 (36%), Positives = 66/110 (60%)
 Frame = +3

Query: 366 KGNECFQKGDYPQAMKHYTEAIKRNPRDAKLYSNRAACYTKLLEFQLALKDCEECIQLEP 425
           +GNE  Q  +Y  A++ +TEAI  +P+D +   NR+ CY +L +++ ALKD E+ I+L  
Sbjct: 390 RGNEMAQVEEYSAAIQLFTEAIALDPKDFRFLGNRSYCYDRLQQYEKALKDAEKAIKLSK 569

Query: 426 TFIKGYTRKAAALEAMKDYTKAMDVYQKALDLDSSCKEAADGYQRCMMAQ 475
            + KGY RK  AL  +  +++A + + + L LD +C+EA    Q+    Q
Sbjct: 570 DWPKGYFRKGRALAGLCKFSEAEESFLQVLKLDKNCEEAVQELQQVRTRQ 719

 Score = 67.8 bits (164), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 39/109 (35%), Positives = 59/109 (54%)
 Frame = +3

Query: 10  KGNKALSAGNIDDALQCYSEAIKLDPQNHVLYSNRSAAYAKKGDYQKAYEDGCKTVDLKP 69
           +GN+         A+Q ++EAI LDP++     NRS  Y +   Y+KA +D  K + L  
Sbjct: 390 RGNEMAQVEEYSAAIQLFTEAIALDPKDFRFLGNRSYCYDRLQQYEKALKDAEKAIKLSK 569

Query: 70  DWGKGYSRKAAALEFLNRFEEAKRTYEEGLKHEANNLQLKEGLQNMEAR 118
           DW KGY RK  AL  L +F EA+ ++ + LK + N  +  + LQ +  R
Sbjct: 570 DWPKGYFRKGRALAGLCKFSEAEESFLQVLKLDKNCEEAVQELQQVRTR 716
>30337
          Length = 493

 Score = 72.0 bits (175), Expect = 6e-13,   Method: Compositional matrix adjust.
 Identities = 37/98 (37%), Positives = 58/98 (59%)
 Frame = -1

Query: 360 ALEEKNKGNECFQKGDYPQAMKHYTEAIKRNPRDAKLYSNRAACYTKLLEFQLALKDCEE 419
           A++ KN+GN+ F    Y  A+  YT+AI +NP  A  ++NRA CY KL  ++LA +DC+ 
Sbjct: 331 AIDLKNQGNKLFAARKYEDAIHCYTKAIMKNPNTATYFTNRALCYIKLRNWELASQDCQR 152

Query: 420 CIQLEPTFIKGYTRKAAALEAMKDYTKAMDVYQKALDL 457
            ++L+   +KG+     AL  +  Y +A+    KA DL
Sbjct: 151 ALELDRNLVKGHFFLGQALVELAMYDEAITHLMKAHDL 38

 Score = 50.4 bits (119), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 27/86 (31%), Positives = 49/86 (56%)
 Frame = -1

Query: 6   ELKEKGNKALSAGNIDDALQCYSEAIKLDPQNHVLYSNRSAAYAKKGDYQKAYEDGCKTV 65
           +LK +GNK  +A   +DA+ CY++AI  +P     ++NR+  Y K  +++ A +D  + +
Sbjct: 325 DLKNQGNKLFAARKYEDAIHCYTKAIMKNPNTATYFTNRALCYIKLRNWELASQDCQRAL 146

Query: 66  DLKPDWGKGYSRKAAALEFLNRFEEA 91
           +L  +  KG+     AL  L  ++EA
Sbjct: 145 ELDRNLVKGHFFLGQALVELAMYDEA 68
>35348
          Length = 627

 Score = 67.4 bits (163), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 39/121 (32%), Positives = 66/121 (54%), Gaps = 5/121 (4%)
 Frame = -2

Query: 7   LKEKGNKALSAGNIDDALQCYSEAIKLDP-----QNHVLYSNRSAAYAKKGDYQKAYEDG 61
           +K +GN    +G   +AL+ YSE + + P     Q  V+ SNR+A   KK DYQKA  D 
Sbjct: 575 VKVRGNDTFKSGQYAEALELYSEGLDICPLKYVQQRSVMLSNRAACRIKKEDYQKAVGDC 396

Query: 62  CKTVDLKPDWGKGYSRKAAALEFLNRFEEAKRTYEEGLKHEANNLQLKEGLQNMEARLAE 121
            K++DL P + K Y R+A A E L + ++A + + + ++ + + +   +    +E  + E
Sbjct: 395 TKSIDLNPAYIKAYFRRADAYEKLEKLDDALKDHRQVVEMDRSQIDSIQACLRLEKEIEE 216

Query: 122 R 122
           R
Sbjct: 215 R 213

 Score = 66.6 bits (161), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 38/118 (32%), Positives = 67/118 (56%), Gaps = 5/118 (4%)
 Frame = -2

Query: 360 ALEEKNKGNECFQKGDYPQAMKHYTEAIKRNP-----RDAKLYSNRAACYTKLLEFQLAL 414
           A++ K +GN+ F+ G Y +A++ Y+E +   P     + + + SNRAAC  K  ++Q A+
Sbjct: 584 AVKVKVRGNDTFKSGQYAEALELYSEGLDICPLKYVQQRSVMLSNRAACRIKKEDYQKAV 405

Query: 415 KDCEECIQLEPTFIKGYTRKAAALEAMKDYTKAMDVYQKALDLDSSCKEAADGYQRCM 472
            DC + I L P +IK Y R+A A E ++    A+  +++ +++D S     D  Q C+
Sbjct: 404 GDCTKSIDLNPAYIKAYFRRADAYEKLEKLDDALKDHRQVVEMDRS---QIDSIQACL 240

 Score = 43.1 bits (100), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 37/134 (27%), Positives = 66/134 (49%), Gaps = 6/134 (4%)
 Frame = -2

Query: 224 QALKEKELGNDAYKKKDFDKALKHYDRAKELDPTNMT-----YITNQAAVHFEKGDYNKC 278
           +A+K K  GND +K   + +AL+ Y    ++ P          ++N+AA   +K DY K 
Sbjct: 587 EAVKVKVRGNDTFKSGQYAEALELYSEGLDICPLKYVQQRSVMLSNRAACRIKKEDYQKA 408

Query: 279 RELCEKAIEVGRENREDYRQIAKAYARIGNSYFKEEKYKDAIHFYNKSLAEHRTP-DVLK 337
              C K+I++            KAY R  ++Y K EK  DA+  + + +   R+  D ++
Sbjct: 407 VGDCTKSIDLN-------PAYIKAYFRRADAYEKLEKLDDALKDHRQVVEMDRSQIDSIQ 249

Query: 338 KCQQAEKILKEQER 351
            C + EK ++E+ +
Sbjct: 248 ACLRLEKEIEERTK 207
>01124
          Length = 1372

 Score = 64.3 bits (155), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 39/117 (33%), Positives = 59/117 (50%), Gaps = 14/117 (11%)
 Frame = -3

Query: 356 NPDLALEEKN------KGNECFQKGDYPQAMKHYTEAIKRNPRDAKLYSNRAACYTKLLE 409
           + DL  EE+N      KGN  F  G+Y  A+  YT A++ NP+   LYSNRAAC+ KL  
Sbjct: 785 DSDLTEEERNPQFLRDKGNGFFASGNYQAAVNVYTHALRLNPKMPSLYSNRAACHLKLRN 606

Query: 410 FQLALKDCEECIQL--------EPTFIKGYTRKAAALEAMKDYTKAMDVYQKALDLD 458
               ++DC + + L          + +K   R+  A   ++ Y + +  Y+ AL LD
Sbjct: 605 LFKCIEDCSKAMDLLSPPVPQNAASRVKAMVRRGTAFCQLEMYVEGLQDYEAALKLD 435

 Score = 59.3 bits (142), Expect = 4e-09,   Method: Compositional matrix adjust.
 Identities = 40/117 (34%), Positives = 59/117 (50%), Gaps = 8/117 (6%)
 Frame = -3

Query: 7   LKEKGNKALSAGNIDDALQCYSEAIKLDPQNHVLYSNRSAAYAKKGDYQKAYEDGCKTVD 66
           L++KGN   ++GN   A+  Y+ A++L+P+   LYSNR+A + K  +  K  ED  K +D
Sbjct: 746 LRDKGNGFFASGNYQAAVNVYTHALRLNPKMPSLYSNRAACHLKLRNLFKCIEDCSKAMD 567

Query: 67  L--------KPDWGKGYSRKAAALEFLNRFEEAKRTYEEGLKHEANNLQLKEGLQNM 115
           L             K   R+  A   L  + E  + YE  LK + NN QLKE  + M
Sbjct: 566 LLSPPVPQNAASRVKAMVRRGTAFCQLEMYVEGLQDYEAALKLDPNNQQLKEDAEKM 396
>35264
          Length = 867

 Score = 63.2 bits (152), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 32/90 (35%), Positives = 50/90 (55%)
 Frame = +3

Query: 371 FQKGDYPQAMKHYTEAIKRNPRDAKLYSNRAACYTKLLEFQLALKDCEECIQLEPTFIKG 430
            Q   Y +A++ YT AI   P  A  Y NRAA Y  L +++  LKD ++ +QL+PTF+KG
Sbjct: 72  LQAAKYKEALECYTCAINLCPSCAAYYGNRAATYMMLKKYREGLKDAQQAVQLDPTFVKG 251

Query: 431 YTRKAAALEAMKDYTKAMDVYQKALDLDSS 460
           Y R+      + +   A   + + L+LD+ 
Sbjct: 252 YIREGKCHLMLGNSMAASSNFNRVLELDAG 341

 Score = 50.1 bits (118), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 29/93 (31%), Positives = 43/93 (46%)
 Frame = +3

Query: 13  KALSAGNIDDALQCYSEAIKLDPQNHVLYSNRSAAYAKKGDYQKAYEDGCKTVDLKPDWG 72
           + L A    +AL+CY+ AI L P     Y NR+A Y     Y++  +D  + V L P + 
Sbjct: 66  RVLQAAKYKEALECYTCAINLCPSCAAYYGNRAATYMMLKKYREGLKDAQQAVQLDPTFV 245

Query: 73  KGYSRKAAALEFLNRFEEAKRTYEEGLKHEANN 105
           KGY R+      L     A   +   L+ +A N
Sbjct: 246 KGYIREGKCHLMLGNSMAASSNFNRVLELDAGN 344
>04645
          Length = 1075

 Score = 62.8 bits (151), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 29/91 (31%), Positives = 56/91 (61%)
 Frame = +3

Query: 1   MEQVNELKEKGNKALSAGNIDDALQCYSEAIKLDPQNHVLYSNRSAAYAKKGDYQKAYED 60
           ++Q ++ + +   A++ G ++DA+  +++AIK +P + +LY+ R +AY K G  +KA  D
Sbjct: 435 IDQASDNRNQAMDAMAEGRLEDAIGFFTDAIKSNPTSALLYAKRGSAYLKMGKPKKAIHD 614

Query: 61  GCKTVDLKPDWGKGYSRKAAALEFLNRFEEA 91
             K ++L PD  +GY  +  A + L  +EE+
Sbjct: 615 CSKAIELNPDSAQGYKWRGKAHKLLGHWEES 707

 Score = 53.5 bits (127), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 30/105 (28%), Positives = 54/105 (51%)
 Frame = +3

Query: 358 DLALEEKNKGNECFQKGDYPQAMKHYTEAIKRNPRDAKLYSNRAACYTKLLEFQLALKDC 417
           D A + +N+  +   +G    A+  +T+AIK NP  A LY+ R + Y K+ + + A+ DC
Sbjct: 438 DQASDNRNQAMDAMAEGRLEDAIGFFTDAIKSNPTSALLYAKRGSAYLKMGKPKKAIHDC 617

Query: 418 EECIQLEPTFIKGYTRKAAALEAMKDYTKAMDVYQKALDLDSSCK 462
            + I+L P   +GY  +  A + +  + ++        DL  +CK
Sbjct: 618 SKAIELNPDSAQGYKWRGKAHKLLGHWEESYH------DLTLACK 734

 Score = 31.6 bits (70), Expect = 0.77,   Method: Compositional matrix adjust.
 Identities = 23/95 (24%), Positives = 43/95 (45%)
 Frame = +3

Query: 224 QALKEKELGNDAYKKKDFDKALKHYDRAKELDPTNMTYITNQAAVHFEKGDYNKCRELCE 283
           QA   +    DA  +   + A+  +  A + +PT+      + + + + G   K    C 
Sbjct: 441 QASDNRNQAMDAMAEGRLEDAIGFFTDAIKSNPTSALLYAKRGSAYLKMGKPKKAIHDCS 620

Query: 284 KAIEVGRENREDYRQIAKAYARIGNSYFKEEKYKD 318
           KAIE+  ++ + Y+   KA+  +G+    EE Y D
Sbjct: 621 KAIELNPDSAQGYKWRGKAHKLLGHW---EESYHD 716
>35341
          Length = 641

 Score = 53.5 bits (127), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 26/75 (34%), Positives = 45/75 (60%)
 Frame = +3

Query: 390 NPRDAKLYSNRAACYTKLLEFQLALKDCEECIQLEPTFIKGYTRKAAALEAMKDYTKAMD 449
           +P +A L +NRA    K+ ++ +A  DC   I L+P ++K Y R+AAA   M+    A++
Sbjct: 12  DPTNALLPANRAMALIKMEKYGVAEVDCTTAITLDPLYVKAYLRRAAARVGMQRLQPALE 191

Query: 450 VYQKALDLDSSCKEA 464
            Y++ L L+ + K+A
Sbjct: 192 DYERVLQLEPNSKQA 236

 Score = 35.4 bits (80), Expect = 0.063,   Method: Compositional matrix adjust.
 Identities = 24/71 (33%), Positives = 32/71 (45%)
 Frame = +3

Query: 355 INPDLALEEKNKGNECFQKGDYPQAMKHYTEAIKRNPRDAKLYSNRAACYTKLLEFQLAL 414
           ++P  AL   N+     +   Y  A    T AI  +P   K Y  RAA    +   Q AL
Sbjct: 9   LDPTNALLPANRAMALIKMEKYGVAEVDCTTAITLDPLYVKAYLRRAAARVGMQRLQPAL 188

Query: 415 KDCEECIQLEP 425
           +D E  +QLEP
Sbjct: 189 EDYERVLQLEP 221
>23484
          Length = 1647

 Score = 51.2 bits (121), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 31/107 (28%), Positives = 52/107 (48%), Gaps = 4/107 (3%)
 Frame = +1

Query: 364 KNKGNECFQKGDYPQAMKHYTEAIKRNP----RDAKLYSNRAACYTKLLEFQLALKDCEE 419
           + +GN+ F+K DY  A+ +Y E IK N     ++A LY+NRAA +  L  ++ A  DC  
Sbjct: 511 REEGNDLFKKKDYRLAVDNYXEGIKSNSPQRLQNAVLYTNRAAAHFHLGNYRSAFNDCFA 690

Query: 420 CIQLEPTFIKGYTRKAAALEAMKDYTKAMDVYQKALDLDSSCKEAAD 466
             + +P  +K   R A   + M  +   +      L ++   K+  D
Sbjct: 691 ARKFKPDHLKALVRGAMCCDKMNKHNDTLRWCDAGLMVEPGHKDLTD 831

 Score = 48.1 bits (113), Expect = 9e-06,   Method: Compositional matrix adjust.
 Identities = 33/107 (30%), Positives = 51/107 (47%), Gaps = 4/107 (3%)
 Frame = +1

Query: 8   KEKGNKALSAGNIDDALQCYSEAIKLDP----QNHVLYSNRSAAYAKKGDYQKAYEDGCK 63
           +E+GN      +   A+  Y E IK +     QN VLY+NR+AA+   G+Y+ A+ D   
Sbjct: 511 REEGNDLFKKKDYRLAVDNYXEGIKSNSPQRLQNAVLYTNRAAAHFHLGNYRSAFNDCFA 690

Query: 64  TVDLKPDWGKGYSRKAAALEFLNRFEEAKRTYEEGLKHEANNLQLKE 110
               KPD  K   R A   + +N+  +  R  + GL  E  +  L +
Sbjct: 691 ARKFKPDHLKALVRGAMCCDKMNKHNDTLRWCDAGLMVEPGHKDLTD 831

 Score = 35.0 bits (79), Expect = 0.083,   Method: Compositional matrix adjust.
 Identities = 22/58 (37%), Positives = 29/58 (50%), Gaps = 4/58 (6%)
 Frame = +1

Query: 229 KELGNDAYKKKDFDKALKHYDRA-KELDP---TNMTYITNQAAVHFEKGDYNKCRELC 282
           +E GND +KKKD+  A+ +Y    K   P    N    TN+AA HF  G+Y      C
Sbjct: 511 REEGNDLFKKKDYRLAVDNYXEGIKSNSPQRLQNAVLYTNRAAAHFHLGNYRSAFNDC 684
>00888
          Length = 970

 Score = 45.4 bits (106), Expect = 6e-05,   Method: Compositional matrix adjust.
 Identities = 33/128 (25%), Positives = 58/128 (45%), Gaps = 16/128 (12%)
 Frame = -3

Query: 364 KNKGNECFQKGDYPQAMKHYTEAIK------RNPRDAKL----------YSNRAACYTKL 407
           K KG   F+KG Y +A+ +Y + +           D++L          + N A C  KL
Sbjct: 728 KEKGTAAFKKGKYQRALTNYEKIVSFLEHESTGLSDSELSDKHQLMVAAFLNIAMCQLKL 549

Query: 408 LEFQLALKDCEECIQLEPTFIKGYTRKAAALEAMKDYTKAMDVYQKALDLDSSCKEAADG 467
           L+++ A + C + + +    +K   R+  A     DYT+A   + K L+L+   K A + 
Sbjct: 548 LDYRQAEETCNKVLAMSTNNVKALFRRGQARLECADYTEAASDFSKVLELEPGNKAAKNQ 369

Query: 468 YQRCMMAQ 475
           +  C+  Q
Sbjct: 368 HIVCLQKQ 345
>13560
          Length = 978

 Score = 44.7 bits (104), Expect = 9e-05,   Method: Compositional matrix adjust.
 Identities = 38/132 (28%), Positives = 55/132 (41%), Gaps = 19/132 (14%)
 Frame = +1

Query: 8   KEKGNKALSAGNIDDALQCYSEAIKL--------------DPQNHV-----LYSNRSAAY 48
           KEKG +    GNI  A   +  AI+L                 +H+      Y N +A  
Sbjct: 202 KEKGAQYFKTGNIFAAFSHFRTAIRLLLSVLPYSFSDDEVASTSHLQLLCQCYLNLAACQ 381

Query: 49  AKKGDYQKAYEDGCKTVDLKPDWGKGYSRKAAALEFLNRFEEAKRTYEEGLKHEANNLQL 108
            K G ++    +    ++L P   K   R+A+A   L     A    E GL+ E NN  L
Sbjct: 382 IKSGHHKHVITNCTHALNLDPANVKALYRRASANVNLGNLLHAHEDLETGLQKEPNNRAL 561

Query: 109 KEGLQNMEARLA 120
            + +QN+ ARLA
Sbjct: 562 LDLMQNVNARLA 597

 Score = 31.2 bits (69), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 23/94 (24%), Positives = 38/94 (40%), Gaps = 19/94 (20%)
 Frame = +1

Query: 363 EKNKGNECFQKGDYPQAMKHYTEAIK---------------RNPRDAKL----YSNRAAC 403
            K KG + F+ G+   A  H+  AI+                +    +L    Y N AAC
Sbjct: 199 HKEKGAQYFKTGNIFAAFSHFRTAIRLLLSVLPYSFSDDEVASTSHLQLLCQCYLNLAAC 378

Query: 404 YTKLLEFQLALKDCEECIQLEPTFIKGYTRKAAA 437
             K    +  + +C   + L+P  +K   R+A+A
Sbjct: 379 QIKSGHHKHVITNCTHALNLDPANVKALYRRASA 480
>03857
          Length = 1696

 Score = 40.8 bits (94), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 32/116 (27%), Positives = 54/116 (46%), Gaps = 19/116 (16%)
 Frame = +1

Query: 359 LALEEKNKGNECFQKGDYPQAMKHYTEAIK---------------RNPRDAKLYS----N 399
           + L+ K  GN  F+ G +  A + Y +A++               +   + +L+     N
Sbjct: 460 VVLDVKQAGNTLFKAGKFGPANRKYKKALRYLQKLDEEQKMSEDQQKAMEKELHIPVSLN 639

Query: 400 RAACYTKLLEFQLALKDCEECIQLEPTFIKGYTRKAAALEAMKDYTKAMDVYQKAL 455
            AAC  KL ++  AL+ C+E ++ +P   K   R+  A    KDY  A+  +QKAL
Sbjct: 640 AAACCLKLNKYNEALEYCQEVLEADPDNSKAQYRQGQAHAGNKDYETALASFQKAL 807
>22027
          Length = 692

 Score = 36.6 bits (83), Expect = 0.026,   Method: Compositional matrix adjust.
 Identities = 19/70 (27%), Positives = 30/70 (42%), Gaps = 10/70 (14%)
 Frame = -3

Query: 1   MEQVNELKEKGNKALSAGNIDDALQCYSEAIKLDPQNH----------VLYSNRSAAYAK 50
           +EQ   L+  GN+    G  D AL CY+ A++  P +           + + NRSAA+  
Sbjct: 285 VEQAEALRTTGNEHFKCGKYDKALSCYNNAVRYAPHSTLDINSCNVLALCFGNRSAAFFH 106

Query: 51  KGDYQKAYED 60
              +     D
Sbjct: 105 LKQFHSCLAD 76
>32109
          Length = 576

 Score = 35.0 bits (79), Expect = 0.068,   Method: Compositional matrix adjust.
 Identities = 19/54 (35%), Positives = 29/54 (53%)
 Frame = +2

Query: 417 CEECIQLEPTFIKGYTRKAAALEAMKDYTKAMDVYQKALDLDSSCKEAADGYQR 470
           C + + L+P  +K    KA AL  M ++ +A  VY +A  LDS+ K  A   +R
Sbjct: 11  CHKALALQPNNVKALYHKAQALHFMSEFEQARGVYLRAQRLDSTNKAIATSLKR 172
>14231
          Length = 975

 Score = 31.2 bits (69), Expect = 1.0,   Method: Compositional matrix adjust.
 Identities = 43/155 (27%), Positives = 57/155 (36%), Gaps = 27/155 (17%)
 Frame = -1

Query: 330 HRTPDVLKKCQQAEKILKEQERLAYINPDLALEEKNKGNECFQKGDYPQAMKHYTEAIKR 389
           HR  D L      E + KE E+ A +      ++ + G+ CF+ G+Y    K       +
Sbjct: 762 HRLADFL------ESVKKEFEKAATVYKS-TCDDYHYGHSCFKYGNYRMTGK----GSSK 616

Query: 390 NPRDAKLYSNRA-------ACYTKLL---------------EFQLALKDCE-----ECIQ 422
           +P  A  Y  +        ACYT  L                 QL    C+      C Q
Sbjct: 615 DPSVALDYFLKGCEAEYVPACYTAALVLHSKKLPTAKDPDKAVQLLTHGCDNKHAASCYQ 436

Query: 423 LEPTFIKGYTRKAAALEAMKDYTKAMDVYQKALDL 457
           L   +I G T   A     KD TKA    QKA DL
Sbjct: 435 LSGWYISG-THAIA-----KDMTKAFQFSQKACDL 349
>10994
          Length = 2182

 Score = 30.8 bits (68), Expect = 1.4,   Method: Compositional matrix adjust.
 Identities = 17/56 (30%), Positives = 29/56 (51%)
 Frame = -3

Query: 232  GNDAYKKKDFDKALKHYDRAKELDPTNMTYITNQAAVHFEKGDYNKCRELCEKAIE 287
            G +  KK    +A++H + A ++DP +   +  + AV+     Y K  E  EKA+E
Sbjct: 1634 GVEMVKKGQHLEAIQHLNLALKIDPLHTEALVARGAVYANNASYGKAIEDFEKALE 1467
>17748
          Length = 621

 Score = 30.8 bits (68), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 14/33 (42%), Positives = 23/33 (69%), Gaps = 1/33 (3%)
 Frame = -3

Query: 2   EQVN-ELKEKGNKALSAGNIDDALQCYSEAIKL 33
           E++N E+K KG K ++ G++DD L C S+  +L
Sbjct: 106 EELNGEIKIKGLKEVTVGSVDDTLDCLSQGAQL 8
>28154
          Length = 374

 Score = 29.3 bits (64), Expect = 4.5,   Method: Composition-based stats.
 Identities = 15/56 (26%), Positives = 28/56 (50%)
 Frame = +1

Query: 374 GDYPQAMKHYTEAIKRNPRDAKLYSNRAACYTKLLEFQLALKDCEECIQLEPTFIK 429
           G+Y +A+  +  A++  P+DA L++   A        + A+      +QL P FI+
Sbjct: 136 GEYNKAVDCFQAALQARPKDALLWNKLGATLANGGRSEEAVDAYHNALQLSPGFIR 303
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31324571|ref|NP_705813.2| CCR4-NOT transcription
complex, subunit 10 [Mus musculus]
         (744 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

26078                                                                  80   3e-15
13404                                                                  65   1e-10
14283                                                                  30   2.5  
17015                                                                  30   3.8  
>26078
          Length = 562

 Score = 80.1 bits (196), Expect = 3e-15,   Method: Compositional matrix adjust.
 Identities = 55/174 (31%), Positives = 94/174 (54%)
 Frame = -1

Query: 519 PSSPLRKQELENLKCSILACSAYVALALGDNLMALNHADQLLQQPKLSGSLKFLGHLYAA 578
           PS P+  + LEN+  +I A  ++V+L LGD++ AL  A QLLQ  +LS + K LGH+YA 
Sbjct: 559 PSKPISLESLENMLAAIYAAHSFVSLRLGDHVTALEMAKQLLQSERLSDAHKLLGHMYAG 380

Query: 579 EALISLDRISDAITHLNPENVTDVSLGISSNEQDQGSDKGENEAMESSGKRAPQCYPSSV 638
           EAL+ ++  S+A  HL P  V+ ++                  A+E   +        S+
Sbjct: 379 EALMMMEMPSEARDHLEPTFVSTLN------------------ALELETR---DWQLKSL 263

Query: 639 NSARTVMLFNLGSAYCLRSEYDKARKCLHQAASMIHPKEVPPEAILLAVYLELQ 692
           ++A+ V+ +NL  A  L+++Y  A+  L    ++ HP  V  ++ +L  Y++L+
Sbjct: 262 DAAQNVVRYNLAVALALQNDYQAAKSLL---TTLTHPI-VTKKSQILQRYIDLK 113
>13404
          Length = 1047

 Score = 64.7 bits (156), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 43/131 (32%), Positives = 69/131 (52%), Gaps = 8/131 (6%)
 Frame = +1

Query: 582 ISLDRISDAITHLNPENVT--DVSL----GISSNEQDQGSDKGENEAMESSGKRAP--QC 633
           +S+DRI+DAI +LNP+ +T  D+S     G +  E+   +DKGE +A +    ++     
Sbjct: 1   VSMDRIADAIGYLNPDTLTPADISTVPPEGKADPEKIDKTDKGEKDAADGGEDKSALIAW 180

Query: 634 YPSSVNSARTVMLFNLGSAYCLRSEYDKARKCLHQAASMIHPKEVPPEAILLAVYLELQN 693
            P  +  A+  +  NL  A+  R+EYDKA K L +  S      +P +   L +YL+L  
Sbjct: 181 IPRDMAKAKAFVQHNLAVAHATRTEYDKAMKYLTE-GSQNSGNPLPAQMYFLKLYLDLME 357

Query: 694 GNTQLALQMIK 704
           G   +A  +IK
Sbjct: 358 GRRHIAQVVIK 390
>14283
          Length = 1061

 Score = 30.4 bits (67), Expect = 2.5,   Method: Composition-based stats.
 Identities = 10/27 (37%), Positives = 17/27 (62%)
 Frame = +1

Query: 290 CLRCMFWNNLGCIHFAMSKHNLGIFYF 316
           C +C+F+ ++ CI F++   NL I  F
Sbjct: 34  CFQCLFYQSVNCIVFSVCSTNLSIVLF 114
>17015
          Length = 612

 Score = 30.0 bits (66), Expect = 3.8,   Method: Composition-based stats.
 Identities = 13/31 (41%), Positives = 19/31 (61%)
 Frame = +2

Query: 243 MNTAGNSAPSLFLKSNFEYLRGNYRKAVKLL 273
           +  A + APSLFL  N  Y + NYR  V+++
Sbjct: 518 LGVAPSPAPSLFLSDNVLYRQTNYRNCVEVM 610
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31981530|ref|NP_542374.2| cask-interacting protein 2
[Mus musculus]
         (1201 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

06253                                                                  80   3e-15
11295                                                                  68   2e-11
34970                                                                  68   2e-11
02114                                                                  67   3e-11
09292                                                                  67   3e-11
14005                                                                  65   1e-10
19166                                                                  64   3e-10
05924                                                                  62   1e-09
25470                                                                  62   2e-09
30978                                                                  56   1e-07
13462                                                                  55   1e-07
00540                                                                  55   1e-07
12417                                                                  55   1e-07
28691                                                                  53   6e-07
08473                                                                  51   3e-06
20792                                                                  44   4e-06
30463                                                                  50   4e-06
09180                                                                  50   4e-06
20036                                                                  49   9e-06
25464                                                                  49   1e-05
05396                                                                  45   1e-04
28113                                                                  45   2e-04
15359                                                                  45   2e-04
38834                                                                  44   5e-04
34789                                                                  43   6e-04
17893                                                                  42   0.002
20884                                                                  41   0.003
02055                                                                  41   0.004
28009                                                                  39   0.008
16561                                                                  39   0.010
33144                                                                  38   0.019
28494                                                                  38   0.024
30217                                                                  38   0.029
17286                                                                  36   0.095
20121                                                                  36   0.098
27252                                                                  35   0.24 
35952                                                                  34   0.30 
07218                                                                  34   0.44 
26032                                                                  33   0.47 
15772                                                                  33   0.69 
21751                                                                  31   2.6  
21532                                                                  30   5.4  
22305                                                                  30   6.4  
>06253
          Length = 1049

 Score = 80.5 bits (197), Expect = 3e-15,   Method: Compositional matrix adjust.
 Identities = 83/269 (30%), Positives = 114/269 (42%), Gaps = 19/269 (7%)
 Frame = -1

Query: 74  TVDIKDSNGMRPLHYAAWQGRLEPVRLLLRASAAVNAASLDGQIPLHLAAQYGHYEVSEM 133
            V  +D  G+ PLH A   G  E V+LLLR  A  NA       PLH AA  G  +V  +
Sbjct: 971 NVHARDDGGLIPLHNACSFGHAEVVQLLLRHGADPNARDNWNYTPLHEAAIKGKIDVCIV 792

Query: 134 LLQHQSNPCLVNKLKKTPLDL------ACEFGRLKVAQLLL-----NSHLCVALLE--GE 180
           LLQ  ++P + N   KT LDL      A   G  K  +LL      N    +ALL     
Sbjct: 791 LLQQCADPNIRNTDGKTALDLADASAKAVLTGEYKKDELLEAARSGNEEQMMALLTPLNV 612

Query: 181 AKDPCDPNYTTPLHLAAKNGHREVIRQLLKAGIEINRQTKTGTA-LHEAALYGKTEVVRL 239
                D   +TPLHLAA      +++ LL+ G +++ + K G   LH A  YG  EV  +
Sbjct: 611 NCHASDGRKSTPLHLAAGYNRTRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHFEVTEM 432

Query: 240 LLEGGVDVNIRNTYNQTALDIVNQFTTSQASREIKQLLREASGILKVRALKDFWNLHDPT 299
           LL  G  VN  + +  T L        S++  E+  LL                   DP 
Sbjct: 431 LLXAGASVNAVDLWQFTPL----HEAASKSRVEVCSLLLAHGA--------------DPN 306

Query: 300 ALNVRAGDVITV-----LEQHPDGRWKGH 323
            +N  +  +I V     L++     +KGH
Sbjct: 305 LVNCHSKSIIDVAPTRELQERIQFEYKGH 219

 Score = 68.6 bits (166), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 49/129 (37%), Positives = 65/129 (50%), Gaps = 1/129 (0%)
 Frame = -1

Query: 148  KKTPLDLACEFGRLKVAQLLLNSHLCVALLEGEAKDPCDPNYTTPLHLAAKNGHREVIRQ 207
            K TPL  A  FGR  V + LL +        G      D     PLH A   GH EV++ 
Sbjct: 1046 KSTPLHFAAGFGRKDVVEHLLEN--------GANVHARDDGGLIPLHNACSFGHAEVVQL 891

Query: 208  LLKAGIEIN-RQTKTGTALHEAALYGKTEVVRLLLEGGVDVNIRNTYNQTALDIVNQFTT 266
            LL+ G + N R     T LHEAA+ GK +V  +LL+   D NIRNT  +TALD+ +    
Sbjct: 890  LLRHGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQQCADPNIRNTDGKTALDLADASAK 711

Query: 267  SQASREIKQ 275
            +  + E K+
Sbjct: 710  AVLTGEYKK 684

 Score = 63.5 bits (153), Expect = 5e-10,   Method: Compositional matrix adjust.
 Identities = 63/203 (31%), Positives = 86/203 (42%), Gaps = 21/203 (10%)
 Frame = -1

Query: 40  LNINYQDADGFSA--LHHXXXXXXXXXXXXXXXXXXTVDIKDSNGMRPLHYAAWQGRLEP 97
           LN+N   +DG  +  LH                    V  KD  G+ PLH A   G  E 
Sbjct: 620 LNVNCHASDGRKSTPLHLAAGYNRTRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHFEV 441

Query: 98  VRLLLRASAAVNAASLDGQIPLHLAAQYGHYEVSEMLLQHQSNPCLVNKLKKTPLDLACE 157
             +LL A A+VNA  L    PLH AA     EV  +LL H ++P LVN   K+ +D+A  
Sbjct: 440 TEMLLXAGASVNAVDLWQFTPLHEAASKSRVEVCSLLLAHGADPNLVNCHSKSIIDVAPT 261

Query: 158 FGRLKVAQLLLNSHLCVALLEGE------------AKDPCD----PNYTTPLHLAAKN-- 199
               +  Q     H   +LLEG             A D  +     N  T LH AA +  
Sbjct: 260 RELQERIQFEYKGH---SLLEGARQADLARVKKYLAVDIVNFKHPYNGDTALHCAAASPF 90

Query: 200 -GHREVIRQLLKAGIEINRQTKT 221
              ++V+  L++ G  +N +TKT
Sbjct: 89  PKRKQVVELLVRKGGNLNEKTKT 21
>11295
          Length = 1179

 Score = 68.2 bits (165), Expect = 2e-11,   Method: Composition-based stats.
 Identities = 53/196 (27%), Positives = 84/196 (42%), Gaps = 27/196 (13%)
 Frame = +1

Query: 79  DSNGMRPLHYAAWQGRLEPVRLLL-RASAAVNAASLDGQIPLHLAAQYGHYEVSEMLLQH 137
           D  G  PLH A W G     RLLL R+   VNA   DG+ PL LA++ G + +   LL H
Sbjct: 265 DVIGHTPLHVACWCGSEGVTRLLLDRSDVDVNALDHDGKXPLRLASECGFHYIIRQLLYH 444

Query: 138 QSNPCLVNKLKKTPLDLACEFGRLKVAQLLL-------------------------NSHL 172
            ++  + +  + TP   A  + R+   +  L                            L
Sbjct: 445 NADHTIRDAAEFTPFHCAIRYCRVLAVKTFLVWFPDLIHSFYNDLSPTFMACLQCDKEML 624

Query: 173 CVALLEGEAKDPCDPNYTTPLHLAAKNGHREVIRQLLKAGIEINRQTKTG-TALHEAALY 231
            + +  G + +  D  + TPLH  ++ GH  +++ LL+   E N     G T L+ A+  
Sbjct: 625 SLLIKFGASVNCADHYHYTPLHYISRRGHLTMLQLLLQGKAEPNVVDDEGITPLYIASCE 804

Query: 232 GKTEVVRLLLEGGVDV 247
           G   +V +LL+ G  +
Sbjct: 805 GHVTIVNILLQSGAKI 852

 Score = 56.6 bits (135), Expect = 6e-08,   Method: Composition-based stats.
 Identities = 62/206 (30%), Positives = 91/206 (44%), Gaps = 7/206 (3%)
 Frame = +1

Query: 79  DSNGMRPLHYAAWQGRLEPVRLLLRA----SAAVNAASLDGQIPLHLAAQYGHYEVSEML 134
           D  G+  LH+A      E   LLL        AVNA S D    LH+A      E++ +L
Sbjct: 55  DHRGLSALHHACIGRNTEVAELLLDGWNGDGIAVNATSNDHVTALHIACCLDDREMASLL 234

Query: 135 LQHQSNPCLVNKLKKTPLDLACEFGRLKVAQLLLN-SHLCVALLEGEAKDPCDPNYTTPL 193
           L++ +    ++ +  TPL +AC  G   V +LLL+ S + V  L+ + K         PL
Sbjct: 235 LKYGAYAMALDVIGHTPLHVACWCGSEGVTRLLLDRSDVDVNALDHDGK--------XPL 390

Query: 194 HLAAKNGHREVIRQLLKAGIEIN-RQTKTGTALHEAALYGKTEVVRLLLEGGVDVNIRNT 252
            LA++ G   +IRQLL    +   R     T  H A  Y +   V+  L    D+ I + 
Sbjct: 391 RLASECGFHYIIRQLLYHNADHTIRDAAEFTPFHCAIRYCRVLAVKTFLVWFPDL-IHSF 567

Query: 253 YNQTALDIVNQFTTS-QASREIKQLL 277
           YN    D+   F    Q  +E+  LL
Sbjct: 568 YN----DLSPTFMACLQCDKEMLSLL 633

 Score = 55.8 bits (133), Expect = 9e-08,   Method: Composition-based stats.
 Identities = 40/125 (32%), Positives = 62/125 (49%)
 Frame = +1

Query: 81  NGMRPLHYAAWQGRLEPVRLLLRASAAVNAASLDGQIPLHLAAQYGHYEVSEMLLQHQSN 140
           N + P   A  Q   E + LL++  A+VN A      PLH  ++ GH  + ++LLQ ++ 
Sbjct: 571 NDLSPTFMACLQCDKEMLSLLIKFGASVNCADHYHYTPLHYISRRGHLTMLQLLLQGKAE 750

Query: 141 PCLVNKLKKTPLDLACEFGRLKVAQLLLNSHLCVALLEGEAKDPCDPNYTTPLHLAAKNG 200
           P +V+    TPL +A   G + +  +LL S   + +       PC  +   P+H A K G
Sbjct: 751 PNVVDDEGITPLYIASCEGHVTIVNILLQSGAKIYM-------PCARD---PVHAACKAG 900

Query: 201 HREVI 205
           H EVI
Sbjct: 901 H-EVI 912

 Score = 47.8 bits (112), Expect = 3e-05,   Method: Composition-based stats.
 Identities = 29/94 (30%), Positives = 47/94 (50%), Gaps = 3/94 (3%)
 Frame = +1

Query: 74  TVDIKDSNGMRPLHYAAWQGRLEPVRLLLRASAAVNAASLDGQIPLHLAAQYGHYEVSEM 133
           +V+  D     PLHY + +G L  ++LLL+  A  N    +G  PL++A+  GH  +  +
Sbjct: 649 SVNCADHYHYTPLHYISRRGHLTMLQLLLQGKAEPNVVDDEGITPLYIASCEGHVTIVNI 828

Query: 134 LLQHQSN---PCLVNKLKKTPLDLACEFGRLKVA 164
           LLQ  +    PC      + P+  AC+ G   +A
Sbjct: 829 LLQSGAKIYMPC-----ARDPVHAACKAGHEVIA 915

 Score = 39.7 bits (91), Expect = 0.007,   Method: Composition-based stats.
 Identities = 61/254 (24%), Positives = 92/254 (36%), Gaps = 33/254 (12%)
 Frame = +1

Query: 42  INYQDADGFSALHHXXXXXXXXXXXXX----XXXXXTVDIKDSNGMRPLHYAAWQGRLEP 97
           I + D  G SALHH                       V+   ++ +  LH A      E 
Sbjct: 43  IYWTDHRGLSALHHACIGRNTEVAELLLDGWNGDGIAVNATSNDHVTALHIACCLDDREM 222

Query: 98  VRLLLRASAAVNAASLDGQIPLHLAAQYGHYEVSEMLLQHQSNPCLVNKLK---KTPLDL 154
             LLL+  A   A  + G  PLH+A   G   V+ +LL        VN L    K PL L
Sbjct: 223 ASLLLKYGAYAMALDVIGHTPLHVACWCGSEGVTRLLLDRSDVD--VNALDHDGKXPLRL 396

Query: 155 ACEFGRLKVAQLLLNSHLCVALLEGEAKDP--CDPNYT---------------------- 190
           A E G   + + LL  +    + +     P  C   Y                       
Sbjct: 397 ASECGFHYIIRQLLYHNADHTIRDAAEFTPFHCAIRYCRVLAVKTFLVWFPDLIHSFYND 576

Query: 191 -TPLHLAAKNGHREVIRQLLKAGIEINRQTKTG-TALHEAALYGKTEVVRLLLEGGVDVN 248
            +P  +A     +E++  L+K G  +N       T LH  +  G   +++LLL+G  + N
Sbjct: 577 LSPTFMACLQCDKEMLSLLIKFGASVNCADHYHYTPLHYISRRGHLTMLQLLLQGKAEPN 756

Query: 249 IRNTYNQTALDIVN 262
           + +    T L I +
Sbjct: 757 VVDDEGITPLYIAS 798
>34970
          Length = 505

 Score = 67.8 bits (164), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 29/50 (58%), Positives = 37/50 (74%)
 Frame = -1

Query: 569 LGLPQYHKQLVSSGYDSMGLVADLTWEELQEIGVNKLGHQKKLMLGVKRL 618
           LGL  Y   L S GYD++  V D+TWE+L+EIG+ KLGHQKK+ML V R+
Sbjct: 496 LGLGMYLDTLASQGYDNIDYVTDITWEDLEEIGIKKLGHQKKIMLAVDRM 347

 Score = 32.7 bits (73), Expect = 0.82,   Method: Compositional matrix adjust.
 Identities = 16/45 (35%), Positives = 25/45 (55%), Gaps = 1/45 (2%)
 Frame = -1

Query: 505 YTAHFLQAGYD-VPTISRMTPEDLTAIGVTKPGHRKKIASEIAQL 548
           Y       GYD +  ++ +T EDL  IG+ K GH+KKI   + ++
Sbjct: 481 YLDTLASQGYDNIDYVTDITWEDLEEIGIKKLGHQKKIMLAVDRM 347
>02114
          Length = 1072

 Score = 67.4 bits (163), Expect = 3e-11,   Method: Compositional matrix adjust.
 Identities = 60/220 (27%), Positives = 92/220 (41%), Gaps = 33/220 (15%)
 Frame = +1

Query: 78  KDSNGMRPLHYAAWQGRLEPVRLLLRASAAVNAASLDGQIPLHLAAQYGHYEVSEMLLQH 137
           KD+ G  PLH A   G    V+ LLR    VN+        +H+++ +G     +ML++ 
Sbjct: 289 KDTRGSTPLHLACAHGHSFCVQTLLRCGVDVNSVDKTSWTSVHVSSYHGRLGCLQMLIKW 468

Query: 138 QSNPCLVNKLKKTPLDLACEFGRLKVAQLLLNSHLC------------------------ 173
            +    ++    TP  LA   G L   + L++S  C                        
Sbjct: 469 GARYDDIDTNGNTPAHLAAMEGHLPCLKFLVSSEGCPEHTLGARNDHGETPRDLAQQFYK 648

Query: 174 ------VALLEGEAKDPCDP-NYTTPLHLAAKNGHREVIRQLLKAG-IEIN-RQTKTGTA 224
                 +  ++ E   P    N   P H+AA NG  + +R L++ G + IN R  K  T 
Sbjct: 649 ENILEYIDHVQHEMDHPEQAENLAFPAHMAAYNGELDHLRILVENGVVNINERDDKGNTL 828

Query: 225 LHEAALYGKTEVVRLLLEGGVDVNIRNTYNQTALDIVNQF 264
            H AA  G   +++ L+E G DV I N   +TA DI  +F
Sbjct: 829 AHRAAGQGHLNILQWLVEMGADVEISNGAGETARDIARRF 948

 Score = 55.5 bits (132), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 39/130 (30%), Positives = 60/130 (46%)
 Frame = +1

Query: 82  GMRPLHYAAWQGRLEPVRLLLRASAAVNAASLDGQIPLHLAAQYGHYEVSEMLLQHQSNP 141
           G  P H AA +G+   ++ L     +++A    G  PLHLA  +GH    + LL+   + 
Sbjct: 202 GWTPAHIAAIRGQEGCIQALSNNGVSMSAKDTRGSTPLHLACAHGHSFCVQTLLRCGVDV 381

Query: 142 CLVNKLKKTPLDLACEFGRLKVAQLLLNSHLCVALLEGEAKDPCDPNYTTPLHLAAKNGH 201
             V+K   T + ++   GRL   Q+L+          G   D  D N  TP HLAA  GH
Sbjct: 382 NSVDKTSWTSVHVSSYHGRLGCLQMLIKW--------GARYDDIDTNGNTPAHLAAMEGH 537

Query: 202 REVIRQLLKA 211
              ++ L+ +
Sbjct: 538 LPCLKFLVSS 567
>09292
          Length = 1486

 Score = 67.4 bits (163), Expect = 3e-11,   Method: Compositional matrix adjust.
 Identities = 66/253 (26%), Positives = 106/253 (41%), Gaps = 31/253 (12%)
 Frame = -2

Query: 50   FSALHHXXXXXXXXXXXXXXXXXXTVDIKDSNGMRPLHYAAWQGRLEPVRLLLRASAAVN 109
            F ALH                    VD +DS+    LH   + G ++   +LL+  A VN
Sbjct: 1458 FCALHCAXQLQDVETLLAYLDIGMHVDTRDSHHETALHAVCYVGSVKMASVLLKHXADVN 1279

Query: 110  AASLDGQIPLHLAAQYGHYEVSEMLLQHQS--------------NPCLVNKLKKT----- 150
            A +   + PLH+ A  GH  + E L++H +              N C+ N          
Sbjct: 1278 ARNNVDRTPLHIXAIEGHLGLVEELVRHGADFNAEDKDHLTPVFNACVKNDTDIVRYLLE 1099

Query: 151  ----------PLDLACEFGRLKVAQLLLNSHLCVALLEGEAKDPCDPNYTTPLHLAAKNG 200
                      P+  A ++G  ++ QLL        L+ G A +   P   +PLH+A +NG
Sbjct: 1098 SGARANTTARPIFHAVKYGYSEIVQLL--------LVHGAAVNSL-PGTKSPLHIACRNG 946

Query: 201  HREVIRQLLKAGIEINRQTKTG-TALHEAALY-GKTEVVRLLLEGGVDVNIRNTYNQTAL 258
            + E+ R ++ AG  +N   K G T LH +       ++VRLL+  G +V   N   Q  L
Sbjct: 945  NIEMARTVIIAGANVNAVDKDGNTPLHISVRAPSSAQLVRLLIRFGANVKWGNDNQQIPL 766

Query: 259  DIVNQFTTSQASR 271
             +   ++  + +R
Sbjct: 765  HLACLYSNLETAR 727

 Score = 63.2 bits (152), Expect = 6e-10,   Method: Compositional matrix adjust.
 Identities = 57/168 (33%), Positives = 84/168 (50%), Gaps = 3/168 (1%)
 Frame = -2

Query: 84   RPLHYAAWQGRLEPVRLLLRASAAVNAASLDG-QIPLHLAAQYGHYEVSEMLLQHQSNPC 142
            RP+ +A   G  E V+LLL   AAVN  SL G + PLH+A + G+ E++  ++   +N  
Sbjct: 1071 RPIFHAVKYGYSEIVQLLLVHGAAVN--SLPGTKSPLHIACRNGNIEMARTVIIAGANVN 898

Query: 143  LVNKLKKTPLDLACEF-GRLKVAQLLLNSHLCVALLEGEAKDPCDPNYTTPLHLAAKNGH 201
             V+K   TPL ++       ++ +LL+          G      + N   PLHLA    +
Sbjct: 897  AVDKDGNTPLHISVRAPSSAQLVRLLIRF--------GANVKWGNDNQQIPLHLACLYSN 742

Query: 202  REVIRQLLKAGIEINR-QTKTGTALHEAALYGKTEVVRLLLEGGVDVN 248
             E  R LL  G   N   +K  T LH A + G  ++VRL+L+G  DVN
Sbjct: 741  LETARLLLHCGSCSNELSSKLWTPLHYAVIGGNVDIVRLVLQGSSDVN 598

 Score = 48.1 bits (113), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 29/83 (34%), Positives = 44/83 (53%)
 Frame = -2

Query: 85  PLHYAAWQGRLEPVRLLLRASAAVNAASLDGQIPLHLAAQYGHYEVSEMLLQHQSNPCLV 144
           PLHYA   G ++ VRL+L+ S+ VN+       PLHLA       ++  LL+H +N  + 
Sbjct: 672 PLHYAVIGGNVDIVRLVLQGSSDVNSPDGRNNAPLHLACMKQCIGIARCLLRHGANVNVS 493

Query: 145 NKLKKTPLDLACEFGRLKVAQLL 167
               +TPL +A     L++  LL
Sbjct: 492 GYNGRTPLHIAISHHNLELVLLL 424

 Score = 48.1 bits (113), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 47/173 (27%), Positives = 67/173 (38%), Gaps = 1/173 (0%)
 Frame = -2

Query: 41  NINYQDADGFSALHHXXXX-XXXXXXXXXXXXXXTVDIKDSNGMRPLHYAAWQGRLEPVR 99
           N+N  D DG + LH                     V   + N   PLH A     LE  R
Sbjct: 906 NVNAVDKDGNTPLHISVRAPSSAQLVRLLIRFGANVKWGNDNQQIPLHLACLYSNLETAR 727

Query: 100 LLLRASAAVNAASLDGQIPLHLAAQYGHYEVSEMLLQHQSNPCLVNKLKKTPLDLACEFG 159
           LLL   +  N  S     PLH A   G+ ++  ++LQ  S+    +     PL LAC   
Sbjct: 726 LLLHCGSCSNELSSKLWTPLHYAVIGGNVDIVRLVLQGSSDVNSPDGRNNAPLHLACMKQ 547

Query: 160 RLKVAQLLLNSHLCVALLEGEAKDPCDPNYTTPLHLAAKNGHREVIRQLLKAG 212
            + +A+ LL          G   +    N  TPLH+A  + + E++  L   G
Sbjct: 546 CIGIARCLLR--------HGANVNVSGYNGRTPLHIAISHHNLELVLLLYMCG 412

 Score = 38.1 bits (87), Expect = 0.023,   Method: Compositional matrix adjust.
 Identities = 23/71 (32%), Positives = 36/71 (50%)
 Frame = -2

Query: 75  VDIKDSNGMRPLHYAAWQGRLEPVRLLLRASAAVNAASLDGQIPLHLAAQYGHYEVSEML 134
           V+  D     PLH A  +  +   R LLR  A VN +  +G+ PLH+A  + + E+  +L
Sbjct: 603 VNSPDGRNNAPLHLACMKQCIGIARCLLRHGANVNVSGYNGRTPLHIAISHHNLELVLLL 424

Query: 135 LQHQSNPCLVN 145
               +N  LV+
Sbjct: 423 YMCGANDQLVD 391
>14005
          Length = 1745

 Score = 65.5 bits (158), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 57/191 (29%), Positives = 94/191 (49%), Gaps = 5/191 (2%)
 Frame = -1

Query: 75   VDIKDSN-GMRP-LHYAAWQGRLEPVRLLLRASAAVNAASLD-GQIPLHLAAQYGHYEVS 131
            +D+ + +  +RP L++A     +E V+ L+R  A VNA S +    P H   + G   ++
Sbjct: 1670 IDVNERDEKLRPALYFACMGNDIELVKQLVRYGARVNAYSTETWWTPFHACCKRGDPRIA 1491

Query: 132  EMLLQHQSNPCLVNKLKKTPLDLACEFGRLKVAQLLLNSHLCVALLEGEAKDPCDPNYTT 191
              LL+H +N        KTPL +AC+  + +VA LL+ S              CD    T
Sbjct: 1490 LYLLRHGANKESRTVDGKTPLVVACKNDKAEVALLLIRS-------GANVNVSCDITANT 1332

Query: 192  PLHLAAKNGHREVIRQLLKAGIEINR-QTKTGTALHEAALYG-KTEVVRLLLEGGVDVNI 249
            P+H A +  + E++++L+  G ++++   K  TALH A++ G K  V+ LL     +VN 
Sbjct: 1331 PVHFACQRPNIELLKRLVLHGADVDKPNAKGHTALHVASVRGFKQHVIYLLDFCDAEVNA 1152

Query: 250  RNTYNQTALDI 260
                   AL I
Sbjct: 1151 ATLKGNNALHI 1119

 Score = 42.7 bits (99), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 29/78 (37%), Positives = 42/78 (53%), Gaps = 1/78 (1%)
 Frame = -1

Query: 75   VDIKDSNGMRPLHYAAWQGRLEPVRLLLR-ASAAVNAASLDGQIPLHLAAQYGHYEVSEM 133
            VD  ++ G   LH A+ +G  + V  LL    A VNAA+L G   LH+A +  H ++ E+
Sbjct: 1262 VDKPNAKGHTALHVASVRGFKQHVIYLLDFCDAEVNAATLKGNNALHIACRGKHADLVEL 1083

Query: 134  LLQHQSNPCLVNKLKKTP 151
            LL   +NP   N+   TP
Sbjct: 1082 LLHKGANPAQRNQRGWTP 1029

 Score = 38.1 bits (87), Expect = 0.019,   Method: Compositional matrix adjust.
 Identities = 25/64 (39%), Positives = 38/64 (59%), Gaps = 2/64 (3%)
 Frame = -1

Query: 191  TPLHLAAKNGHREVIRQLLKA-GIEIN-RQTKTGTALHEAALYGKTEVVRLLLEGGVDVN 248
            TPL +A++ GH  V+ +LLK  GI++N R  K   AL+ A +    E+V+ L+  G  VN
Sbjct: 1739 TPLIIASRMGHLAVVSELLKVPGIDVNERDEKLRPALYFACMGNDIELVKQLVRYGARVN 1560

Query: 249  IRNT 252
              +T
Sbjct: 1559 AYST 1548
>19166
          Length = 447

 Score = 64.3 bits (155), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 41/132 (31%), Positives = 68/132 (51%)
 Frame = +1

Query: 81  NGMRPLHYAAWQGRLEPVRLLLRASAAVNAASLDGQIPLHLAAQYGHYEVSEMLLQHQSN 140
           NG  PLH A  + R++ V LLL+  A+++A +  G  PLH+++  GH  +   L+QH + 
Sbjct: 55  NGFTPLHIACKKNRIKVVELLLKYGASIDATTESGLTPLHVSSFMGHMNIVIYLIQHNAY 234

Query: 141 PCLVNKLKKTPLDLACEFGRLKVAQLLLNSHLCVALLEGEAKDPCDPNYTTPLHLAAKNG 200
           P       +T L LA    +  + ++LL +        G A D       TPLH+A++ G
Sbjct: 235 PDTPTVRGETSLHLAARANQTDIIRILLRN--------GAAVDARAREQQTPLHIASRLG 390

Query: 201 HREVIRQLLKAG 212
           + + +  LL+ G
Sbjct: 391 NVDNVVLLLQHG 426

 Score = 52.8 bits (125), Expect = 9e-07,   Method: Compositional matrix adjust.
 Identities = 44/149 (29%), Positives = 75/149 (50%), Gaps = 3/149 (2%)
 Frame = +1

Query: 99  RLLLRASAAVNAASLDGQIPLHLAAQYGHYEVSEMLLQHQSNPCLVNKLKKTPLDLACEF 158
           +LLL      N+ +L+G  PLH+A +    +V E+LL++ ++     +   TPL ++   
Sbjct: 10  KLLLDRKCEPNSRALNGFTPLHIACKKNRIKVVELLLKYGASIDATTESGLTPLHVSSFM 189

Query: 159 GRLKVAQLLL--NSHLCVALLEGEAKDPCDPNYTTPLHLAAKNGHREVIRQLLKAGIEIN 216
           G + +   L+  N++     + GE          T LHLAA+    ++IR LL+ G  ++
Sbjct: 190 GHMNIVIYLIQHNAYPDTPTVRGE----------TSLHLAARANQTDIIRILLRNGAAVD 339

Query: 217 -RQTKTGTALHEAALYGKTEVVRLLLEGG 244
            R  +  T LH A+  G  + V LLL+ G
Sbjct: 340 ARAREQQTPLHIASRLGNVDNVVLLLQHG 426

 Score = 46.2 bits (108), Expect = 9e-05,   Method: Compositional matrix adjust.
 Identities = 30/126 (23%), Positives = 60/126 (47%)
 Frame = +1

Query: 43  NYQDADGFSALHHXXXXXXXXXXXXXXXXXXTVDIKDSNGMRPLHYAAWQGRLEPVRLLL 102
           N +  +GF+ LH                   ++D    +G+ PLH +++ G +  V  L+
Sbjct: 40  NSRALNGFTPLHIACKKNRIKVVELLLKYGASIDATTESGLTPLHVSSFMGHMNIVIYLI 219

Query: 103 RASAAVNAASLDGQIPLHLAAQYGHYEVSEMLLQHQSNPCLVNKLKKTPLDLACEFGRLK 162
           + +A  +  ++ G+  LHLAA+    ++  +LL++ +      + ++TPL +A   G + 
Sbjct: 220 QHNAYPDTPTVRGETSLHLAARANQTDIIRILLRNGAAVDARAREQQTPLHIASRLGNVD 399

Query: 163 VAQLLL 168
              LLL
Sbjct: 400 NVVLLL 417
>05924
          Length = 704

 Score = 62.4 bits (150), Expect = 1e-09,   Method: Composition-based stats.
 Identities = 50/168 (29%), Positives = 85/168 (50%), Gaps = 4/168 (2%)
 Frame = +1

Query: 86  LHYAAWQGRLEPVRLLLRASAAVNAASLDGQIPLHLAAQYGHYEVSEMLLQHQSNPCLVN 145
           LH A      + V++L++A A  N+ + DG+  LHLA + G+  + ++L+   ++   VN
Sbjct: 76  LHEAVSMASEDLVQMLIKAGANANSTNQDGRTALHLACRGGYTNIVQILIAAGTD---VN 246

Query: 146 KLK---KTPLDLACEFGRLKVAQLLLNSHLCVALLEGEAKDPCDPNYTTPLHLAAKNGHR 202
           +     KT L +A   G  +V   L+N+        G   +  D    +PL+ AA++ + 
Sbjct: 247 RRTVDGKTCLHVAVWRGHTEVVVKLVNA--------GADVNIPDSVGCSPLYWAARSNYT 402

Query: 203 EVIRQLLKAGIEINRQTKTG-TALHEAALYGKTEVVRLLLEGGVDVNI 249
            ++  L+ AG ++N + K+  T LH A   G   VVR LL  G + NI
Sbjct: 403 AILTVLVNAGAKVNYRVKSKWTPLHAALHLGHMGVVRYLLLQGAETNI 546

 Score = 48.5 bits (114), Expect = 2e-05,   Method: Composition-based stats.
 Identities = 51/187 (27%), Positives = 76/187 (40%), Gaps = 6/187 (3%)
 Frame = +1

Query: 41  NINYQDADGFSALHHXXXXXXXXXXXXXXXXXXTVDIKDSNGMRPLHYAAWQGRLEPVRL 100
           N N  + DG +ALH                    V+ +  +G   LH A W+G  E V  
Sbjct: 139 NANSTNQDGRTALHLACRGGYTNIVQILIAAGTDVNRRTVDGKTCLHVAVWRGHTEVVVK 318

Query: 101 LLRASAAVNAASLDGQIPLHLAAQYGHYEVSEMLLQHQSNPCLVNKLKKTPLDLACEFGR 160
           L+ A A VN     G  PL+ AA+  +  +  +L+   +      K K TPL  A   G 
Sbjct: 319 LVNAGADVNIPDSVGCSPLYWAARSNYTAILTVLVNAGAKVNYRVKSKWTPLHAALHLGH 498

Query: 161 LKVAQLLLNSHLCVALLEGEAKDPC--DPNYTTPL----HLAAKNGHREVIRQLLKAGIE 214
           + V + L        LL+G   +    D    + L    HL+ K   R  +  L+KAG  
Sbjct: 499 MGVVRYL--------LLQGAETNITVQDKTVVSLLMDNEHLSHKERER-TLAMLVKAGYN 651

Query: 215 INRQTKT 221
           +++ T T
Sbjct: 652 LHKDTWT 672

 Score = 46.6 bits (109), Expect = 6e-05,   Method: Composition-based stats.
 Identities = 26/72 (36%), Positives = 39/72 (54%), Gaps = 1/72 (1%)
 Frame = +1

Query: 190 TTPLHLAAKNGHREVIRQLLKAGIEINRQTKTG-TALHEAALYGKTEVVRLLLEGGVDVN 248
           +T LH A      ++++ L+KAG   N   + G TALH A   G T +V++L+  G DVN
Sbjct: 67  STLLHEAVSMASEDLVQMLIKAGANANSTNQDGRTALHLACRGGYTNIVQILIAAGTDVN 246

Query: 249 IRNTYNQTALDI 260
            R    +T L +
Sbjct: 247 RRTVDGKTCLHV 282

 Score = 30.0 bits (66), Expect = 6.1,   Method: Composition-based stats.
 Identities = 18/46 (39%), Positives = 27/46 (58%)
 Frame = +1

Query: 235 EVVRLLLEGGVDVNIRNTYNQTALDIVNQFTTSQASREIKQLLREA 280
           + V+ L++GGVDVN R  Y+ T L        S AS ++ Q+L +A
Sbjct: 7   KAVQRLVKGGVDVNARFWYDSTLL----HEAVSMASEDLVQMLIKA 132
>25470
          Length = 400

 Score = 61.6 bits (148), Expect = 2e-09,   Method: Composition-based stats.
 Identities = 46/114 (40%), Positives = 59/114 (51%), Gaps = 1/114 (0%)
 Frame = -3

Query: 150 TPLDLACEFGRLKVAQLLLNSHLCVALLEGEAKDPCDPNYTTPLHLAAKNGHREVIRQLL 209
           TP  LA  FGR  V + LL +        G      D     PLH A   GH EV++ LL
Sbjct: 389 TP-SLAAGFGRKDVVEHLLEN--------GANVHARDDGGLIPLHNACSFGHAEVVQLLL 237

Query: 210 KAGIEIN-RQTKTGTALHEAALYGKTEVVRLLLEGGVDVNIRNTYNQTALDIVN 262
           + G + N R     T LHEAA+ GK +V  +LL+   D NIRNT  +TALD+ +
Sbjct: 236 RHGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQQCADPNIRNTDGKTALDLAD 75

 Score = 52.4 bits (124), Expect = 1e-06,   Method: Composition-based stats.
 Identities = 35/81 (43%), Positives = 43/81 (53%)
 Frame = -3

Query: 75  VDIKDSNGMRPLHYAAWQGRLEPVRLLLRASAAVNAASLDGQIPLHLAAQYGHYEVSEML 134
           V  +D  G+ PLH A   G  E V+LLLR  A  NA       PLH AA  G  +V  +L
Sbjct: 320 VHARDDGGLIPLHNACSFGHAEVVQLLLRHGADPNARDNWNYTPLHEAAIKGKIDVCIVL 141

Query: 135 LQHQSNPCLVNKLKKTPLDLA 155
           LQ  ++P + N   KT LDLA
Sbjct: 140 LQQCADPNIRNTDGKTALDLA 78

 Score = 50.4 bits (119), Expect = 4e-06,   Method: Composition-based stats.
 Identities = 32/80 (40%), Positives = 44/80 (55%)
 Frame = -3

Query: 89  AAWQGRLEPVRLLLRASAAVNAASLDGQIPLHLAAQYGHYEVSEMLLQHQSNPCLVNKLK 148
           AA  GR + V  LL   A V+A    G IPLH A  +GH EV ++LL+H ++P   +   
Sbjct: 377 AAGFGRKDVVEHLLENGANVHARDDGGLIPLHNACSFGHAEVVQLLLRHGADPNARDNWN 198

Query: 149 KTPLDLACEFGRLKVAQLLL 168
            TPL  A   G++ V  +LL
Sbjct: 197 YTPLHEAAIKGKIDVCIVLL 138
>30978
          Length = 566

 Score = 55.8 bits (133), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 35/100 (35%), Positives = 53/100 (53%), Gaps = 2/100 (2%)
 Frame = -2

Query: 186 DPNYTTPLHLAAKNGHREVIRQLLKA-GIEINRQTKTG-TALHEAALYGKTEVVRLLLEG 243
           D   +TPLH A   GH + ++ LL     E+N Q K G TALH AA     E V++LL  
Sbjct: 481 DKAGSTPLHWAGHGGHMDCLQVLLSEPKCEVNVQNKLGDTALHSAAWKNHVEAVKMLLGK 302

Query: 244 GVDVNIRNTYNQTALDIVNQFTTSQASREIKQLLREASGI 283
           G  V++RN   + A+++           E+  +LR+A+G+
Sbjct: 301 GARVDLRNNEKKLAVELTK-------DPEVAAMLRQAAGV 203
>13462
          Length = 1388

 Score = 55.5 bits (132), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 56/194 (28%), Positives = 87/194 (44%), Gaps = 6/194 (3%)
 Frame = +3

Query: 84  RPLHYAAWQ--GRLEPVRLLLRASAAVNAASLDGQIPLHLAAQYGHYEVSEMLLQHQSNP 141
           RPLHYA+    G L  V +LL   A  N    DG   LHLA    + +V  +LL+   + 
Sbjct: 183 RPLHYASHHSNGNLGIVSMLLAYGAQPNVQDEDGNTALHLACSESNVDVVRLLLEWGGDV 362

Query: 142 CLVNKLKKTPLDLACEFGRLKVAQLLLNSHLCVALLEGEAKDPCDPNYT--TPLHLAAKN 199
            + +   +TPL  AC    +++  LLL++               DPN++   PL +  + 
Sbjct: 363 AVADIDNETPLVRACLANSVELVDLLLHA-------------GSDPNHSHGRPLEIVVRA 503

Query: 200 GHREVIRQLLKAGIEINRQTKTGTALHEAALYGKTEVVRLLLEGGVDVNIRNTYNQTALD 259
              E ++ L+ AG     Q    T L  A+ +   +++++L   GVDVN       TAL 
Sbjct: 504 PSLESLKLLIGAG----AQVTGNTYLSFASEHNYLDMMKVLHNYGVDVNGTGRLGLTALH 671

Query: 260 --IVNQFTTSQASR 271
              ++Q  T  A R
Sbjct: 672 HACISQEATHDAVR 713

 Score = 50.8 bits (120), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 58/196 (29%), Positives = 85/196 (43%), Gaps = 23/196 (11%)
 Frame = +3

Query: 76  DIKDSNGMRPLHYAAWQGRLEPVRLLLRASAAVNAASLDGQIPLHLAAQYGHYEVSEMLL 135
           +++D +G   LH A  +  ++ VRLLL     V  A +D + PL  A      E+ ++LL
Sbjct: 264 NVQDEDGNTALHLACSESNVDVVRLLLEWGGDVAVADIDNETPLVRACLANSVELVDLLL 443

Query: 136 QHQSNPCLVNKLKKTPLDLACEFGRLKVAQLLL--------NSHLCVA-------LLEGE 180
              S+P   N     PL++      L+  +LL+        N++L  A       +++  
Sbjct: 444 HAGSDP---NHSHGRPLEIVVRAPSLESLKLLIGAGAQVTGNTYLSFASEHNYLDMMKVL 614

Query: 181 AKDPCDPNYT-----TPLHLA--AKNGHREVIRQLLKAGIEINRQTKTG-TALHEAALYG 232
                D N T     T LH A  ++    + +R LL  G   N  T TG T LH A    
Sbjct: 615 HNYGVDVNGTGRLGLTALHHACISQEATHDAVRLLLLWGSNPNLVTGTGDTPLHFACQTF 794

Query: 233 KTEVVRLLLEGGVDVN 248
               VRLLL  G DVN
Sbjct: 795 AVSKVRLLLMYGADVN 842

 Score = 38.5 bits (88), Expect = 0.015,   Method: Compositional matrix adjust.
 Identities = 43/165 (26%), Positives = 69/165 (41%), Gaps = 6/165 (3%)
 Frame = +3

Query: 82  GMRPLHYAAWQGRLEPVRLLLRASAAVNAASLDGQIPLHLA--AQYGHYEVSEMLLQHQS 139
           G   L +A+    L+ +++L      VN     G   LH A  +Q   ++   +LL   S
Sbjct: 555 GNTYLSFASEHNYLDMMKVLHNYGVDVNGTGRLGLTALHHACISQEATHDAVRLLLLWGS 734

Query: 140 NPCLVNKLKKTPLDLACEFGRLKVAQLLLNSHLCVALLEGEAKDPCDPNYTTPLHLAAKN 199
           NP LV     TPL  AC+   +   +LLL     V  ++G    P     TT        
Sbjct: 735 NPNLVTGTGDTPLHFACQTFAVSKVRLLLMYGADVNQIDGTHTSPLIAALTTRRQPQNDA 914

Query: 200 GHREVIRQLLKAGIEIN----RQTKTGTALHEAALYGKTEVVRLL 240
            + ++IR LL AG  ++     + K      +++   K E+ +LL
Sbjct: 915 SYLDLIRLLLAAGARLSSAVLERIKVLIVYLQSSATDKEELFQLL 1049
>00540
          Length = 3034

 Score = 55.5 bits (132), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 41/138 (29%), Positives = 63/138 (45%)
 Frame = -2

Query: 106  AAVNAASLDGQIPLHLAAQYGHYEVSEMLLQHQSNPCLVNKLKKTPLDLACEFGRLKVAQ 165
            A VN  +     PL  A   GH EV + L++H++   + N    T L +AC  G L V +
Sbjct: 2997 AEVNQTTRSNSTPLRAACYDGHLEVVQFLVEHKAEIEIANSHGHTCLMIACYRGHLDVVE 2818

Query: 166  LLLNSHLCVALLEGEAKDPCDPNYTTPLHLAAKNGHREVIRQLLKAGIEINRQTKTGTAL 225
             LL          G   +       T LH +A++G   +++ LL  G ++ +     T L
Sbjct: 2817 YLLYL--------GAQVNRRSVKGNTALHDSAESGKLSIMKLLLSKGAKMAKDAYGQTPL 2662

Query: 226  HEAALYGKTEVVRLLLEG 243
              AA+ G  E+VR L+ G
Sbjct: 2661 SAAAMTGHEEIVRYLISG 2608

 Score = 53.9 bits (128), Expect = 4e-07,   Method: Compositional matrix adjust.
 Identities = 39/111 (35%), Positives = 61/111 (54%), Gaps = 2/111 (1%)
 Frame = -2

Query: 150  TPLDLACEFGRLKVAQLLLNSHLCVALLEGEAK-DPCDPNYTTPLHLAAKNGHREVIRQL 208
            TPL  AC  G L+V Q L+         E +A+ +  + +  T L +A   GH +V+  L
Sbjct: 2964 TPLRAACYDGHLEVVQFLV---------EHKAEIEIANSHGHTCLMIACYRGHLDVVEYL 2812

Query: 209  LKAGIEINRQTKTG-TALHEAALYGKTEVVRLLLEGGVDVNIRNTYNQTAL 258
            L  G ++NR++  G TALH++A  GK  +++LLL  G  +  ++ Y QT L
Sbjct: 2811 LYLGAQVNRRSVKGNTALHDSAESGKLSIMKLLLSKGAKMA-KDAYGQTPL 2662

 Score = 52.0 bits (123), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 40/125 (32%), Positives = 57/125 (45%)
 Frame = -2

Query: 85   PLHYAAWQGRLEPVRLLLRASAAVNAASLDGQIPLHLAAQYGHYEVSEMLLQHQSNPCLV 144
            PL  A + G LE V+ L+   A +  A+  G   L +A   GH +V E LL   +     
Sbjct: 2961 PLRAACYDGHLEVVQFLVEHKAEIEIANSHGHTCLMIACYRGHLDVVEYLLYLGAQVNRR 2782

Query: 145  NKLKKTPLDLACEFGRLKVAQLLLNSHLCVALLEGEAKDPCDPNYTTPLHLAAKNGHREV 204
            +    T L  + E G+L + +LLL+           AK   D    TPL  AA  GH E+
Sbjct: 2781 SVKGNTALHDSAESGKLSIMKLLLSK---------GAKMAKDAYGQTPLSAAAMTGHEEI 2629

Query: 205  IRQLL 209
            +R L+
Sbjct: 2628 VRYLI 2614
>12417
          Length = 954

 Score = 55.5 bits (132), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 30/85 (35%), Positives = 46/85 (54%), Gaps = 1/85 (1%)
 Frame = +2

Query: 190 TTPLHLAAKNGHREVIRQLLKAGIEINRQTKTG-TALHEAALYGKTEVVRLLLEGGVDVN 248
           +  L +AA  G  ++  QL++ G ++N  T+ G T LH A+  G   +V LLLE G D++
Sbjct: 236 SVALAMAANRGLDKMCSQLIQTGADVNSATEHGRTPLHXASAQGHGHIVDLLLEKGADID 415

Query: 249 IRNTYNQTALDIVNQFTTSQASREI 273
             + Y  TAL I +QF      R +
Sbjct: 416 AEDDYGDTALSIADQFGFKSCGRXL 490

 Score = 38.5 bits (88), Expect = 0.016,   Method: Compositional matrix adjust.
 Identities = 21/71 (29%), Positives = 37/71 (52%)
 Frame = +2

Query: 101 LLRASAAVNAASLDGQIPLHLAAQYGHYEVSEMLLQHQSNPCLVNKLKKTPLDLACEFGR 160
           L++  A VN+A+  G+ PLH A+  GH  + ++LL+  ++    +    T L +A +FG 
Sbjct: 290 LIQTGADVNSATEHGRTPLHXASAQGHGHIVDLLLEKGADIDAEDDYGDTALSIADQFGF 469

Query: 161 LKVAQLLLNSH 171
               + L   H
Sbjct: 470 KSCGRXLFLFH 502

 Score = 31.6 bits (70), Expect = 1.8,   Method: Compositional matrix adjust.
 Identities = 18/46 (39%), Positives = 24/46 (52%)
 Frame = +2

Query: 81  NGMRPLHYAAWQGRLEPVRLLLRASAAVNAASLDGQIPLHLAAQYG 126
           +G  PLH A+ QG    V LLL   A ++A    G   L +A Q+G
Sbjct: 329 HGRTPLHXASAQGHGHIVDLLLEKGADIDAEDDYGDTALSIADQFG 466
>28691
          Length = 562

 Score = 53.1 bits (126), Expect = 6e-07,   Method: Composition-based stats.
 Identities = 37/101 (36%), Positives = 53/101 (52%), Gaps = 15/101 (14%)
 Frame = +1

Query: 193 LHLAAKNGHREVIRQLLKAGIEINRQ----TKTGTALHEAALYGKTEV--VRLLLEGGVD 246
           LHLAAKN H + I  L++AG ++N +     K  TALHEA   G + V  V  LL  G D
Sbjct: 130 LHLAAKNKHVDCIPVLVQAGADVNAKGPSTIKGNTALHEAVSVGASNVDSVDALLSCGAD 309

Query: 247 VNIRNTYNQTALD---------IVNQFTTSQASREIKQLLR 278
            NI N   +TA D         IV +F  +    ++++++R
Sbjct: 310 QNIXNEKGETAYDLASKAGYENIVKRFAAAMGQSQLQKMIR 432
>08473
          Length = 942

 Score = 51.2 bits (121), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 47/167 (28%), Positives = 67/167 (40%), Gaps = 1/167 (0%)
 Frame = -1

Query: 75  VDIKDSNGMRPLHYAAWQGRLEPVRLLLRASAAVNAASLDGQIPLHLAAQYGHYEVSEML 134
           VD++DSN M  LH+A                     A L             HY     L
Sbjct: 939 VDMRDSNDMTALHHAC--------------------AGL-------------HYGCVHAL 859

Query: 135 LQHQSNPCLVNKLKKTPLDLACEFGRLKVAQLLLNSHLCVALLEGEAKDPCDPNYTTPLH 194
           LQ  +NP  +    KTPL  A   G + + +LL++        +G   +  D    TPL 
Sbjct: 858 LQGGANPTCMEMGGKTPLFYAAHRGEISICKLLVD--------KGANVNAADKMLITPLM 703

Query: 195 LAAKNGHREVIRQLLKAGIEINRQTKTG-TALHEAALYGKTEVVRLL 240
           +AA+ G+RE +  LLK G   N   + G  AL+ A   G  E+  + 
Sbjct: 702 VAAREGNREAVEFLLKRGANPNTADREGHLALYYAMAAGHPELREVF 562

 Score = 48.5 bits (114), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 34/130 (26%), Positives = 58/130 (44%)
 Frame = -1

Query: 41  NINYQDADGFSALHHXXXXXXXXXXXXXXXXXXTVDIKDSNGMRPLHYAAWQGRLEPVRL 100
           +++ +D++  +ALHH                       +  G  PL YAA +G +   +L
Sbjct: 942 DVDMRDSNDMTALHHACAGLHYGCVHALLQGGANPTCMEMGGKTPLFYAAHRGEISICKL 763

Query: 101 LLRASAAVNAASLDGQIPLHLAAQYGHYEVSEMLLQHQSNPCLVNKLKKTPLDLACEFGR 160
           L+   A VNAA      PL +AA+ G+ E  E LL+  +NP   ++     L  A   G 
Sbjct: 762 LVDKGANVNAADKMLITPLMVAAREGNREAVEFLLKRGANPNTADREGHLALYYAMAAGH 583

Query: 161 LKVAQLLLNS 170
            ++ ++  N+
Sbjct: 582 PELREVFANA 553
>20792
          Length = 441

 Score = 42.7 bits (99), Expect(2) = 4e-06,   Method: Composition-based stats.
 Identities = 28/91 (30%), Positives = 43/91 (47%), Gaps = 2/91 (2%)
 Frame = +2

Query: 75  VDIKDSN--GMRPLHYAAWQGRLEPVRLLLRASAAVNAASLDGQIPLHLAAQYGHYEVSE 132
           VD++  N  G +PLH  A  G+L+ +  LL+    V+        PL LA       V  
Sbjct: 50  VDLQIGNFEGKKPLHETAQFGQLDCMNFLLQRGVQVDCLKRADWTPLMLACTKCQLPVIS 229

Query: 133 MLLQHQSNPCLVNKLKKTPLDLACEFGRLKV 163
           +LL+H ++P LVNK       +A   G + +
Sbjct: 230 LLLKHGADPALVNKDGWNSFHIAAREGHVDI 322

 Score = 27.3 bits (59), Expect(2) = 4e-06,   Method: Compositional matrix adjust.
 Identities = 12/22 (54%), Positives = 15/22 (68%)
 Frame = +3

Query: 188 NYTTPLHLAAKNGHREVIRQLL 209
           N  TPLH AA +GH E +R +L
Sbjct: 375 NSRTPLHTAALHGHSEAVRFML 440

 Score = 44.3 bits (103), Expect = 3e-04,   Method: Composition-based stats.
 Identities = 28/96 (29%), Positives = 45/96 (46%)
 Frame = +2

Query: 111 ASLDGQIPLHLAAQYGHYEVSEMLLQHQSNPCLVNKLKKTPLDLACEFGRLKVAQLLLNS 170
            + +G+ PLH  AQ+G  +    LLQ       + +   TPL LAC   +L V  LLL  
Sbjct: 65  GNFEGKKPLHETAQFGQLDCMNFLLQRGVQVDCLKRADWTPLMLACTKCQLPVISLLLKH 244

Query: 171 HLCVALLEGEAKDPCDPNYTTPLHLAAKNGHREVIR 206
               AL+  +  +          H+AA+ GH ++++
Sbjct: 245 GADPALVNKDGWN--------SFHIAAREGHVDILK 328
>30463
          Length = 412

 Score = 50.4 bits (119), Expect = 4e-06,   Method: Composition-based stats.
 Identities = 30/102 (29%), Positives = 52/102 (50%)
 Frame = -1

Query: 77  IKDSNGMRPLHYAAWQGRLEPVRLLLRASAAVNAASLDGQIPLHLAAQYGHYEVSEMLLQ 136
           ++   G    H AA  G    V +L    A+++  ++D Q PLHLA+  GH E  + L+ 
Sbjct: 403 LETPTGYTATHLAAMNGHSNAVMVLNIMGASIDCRTVDKQTPLHLASSAGHIECVKCLVA 224

Query: 137 HQSNPCLVNKLKKTPLDLACEFGRLKVAQLLLNSHLCVALLE 178
           ++++    +   +T  DLA ++G+  VA  L   H C+  L+
Sbjct: 223 NKASLTAEDAFSRTAYDLADQYGQNDVADFL---HHCLLDLD 107

 Score = 43.5 bits (101), Expect = 5e-04,   Method: Composition-based stats.
 Identities = 25/79 (31%), Positives = 38/79 (48%), Gaps = 1/79 (1%)
 Frame = -1

Query: 187 PNYTTPLHLAAKNGHREVIRQLLKAGIEIN-RQTKTGTALHEAALYGKTEVVRLLLEGGV 245
           P   T  HLAA NGH   +  L   G  I+ R     T LH A+  G  E V+ L+    
Sbjct: 394 PTGYTATHLAAMNGHSNAVMVLNIMGASIDCRTVDKQTPLHLASSAGHIECVKCLVANKA 215

Query: 246 DVNIRNTYNQTALDIVNQF 264
            +   + +++TA D+ +Q+
Sbjct: 214 SLTAEDAFSRTAYDLADQY 158

 Score = 36.6 bits (83), Expect = 0.070,   Method: Composition-based stats.
 Identities = 21/86 (24%), Positives = 37/86 (43%)
 Frame = -1

Query: 49  GFSALHHXXXXXXXXXXXXXXXXXXTVDIKDSNGMRPLHYAAWQGRLEPVRLLLRASAAV 108
           G++A H                   ++D +  +   PLH A+  G +E V+ L+   A++
Sbjct: 388 GYTATHLAAMNGHSNAVMVLNIMGASIDCRTVDKQTPLHLASSAGHIECVKCLVANKASL 209

Query: 109 NAASLDGQIPLHLAAQYGHYEVSEML 134
            A     +    LA QYG  +V++ L
Sbjct: 208 TAEDAFSRTAYDLADQYGQNDVADFL 131
>09180
          Length = 610

 Score = 50.4 bits (119), Expect = 4e-06,   Method: Composition-based stats.
 Identities = 24/74 (32%), Positives = 46/74 (62%), Gaps = 1/74 (1%)
 Frame = +3

Query: 191 TPLHLAAKNGHREVIRQLLKAGIEINRQTKTG-TALHEAALYGKTEVVRLLLEGGVDVNI 249
           T LH++A  G+  V+  LL+AG++IN Q   G T+LH A  +G+ +  ++L++   D+++
Sbjct: 171 TALHVSAAKGYINVMNVLLQAGVDINAQDADGWTSLHAAVHWGQEDSCQVLVDHFCDMDV 350

Query: 250 RNTYNQTALDIVNQ 263
           +N    T  D+ ++
Sbjct: 351 KNNAGHTVFDLADK 392
>20036
          Length = 1849

 Score = 49.3 bits (116), Expect = 9e-06,   Method: Compositional matrix adjust.
 Identities = 44/136 (32%), Positives = 65/136 (47%), Gaps = 6/136 (4%)
 Frame = +3

Query: 129 EVSEMLLQHQSNPCLVNKLKKTPLDLACEFGRLKVAQLLLNSHLCVALLEGEAKDPCDPN 188
           E+S  LL++  N  LV+    + +          +  LLL++ +C      + K P    
Sbjct: 834 EISHRLLEYIVN--LVDSNGNSAIHYCVSHCNFDIVGLLLDTEVC------DVKRPNKAG 989

Query: 189 YT----TPLHLAAKNGHREVIRQLLKAGIEINR-QTKTG-TALHEAALYGKTEVVRLLLE 242
           YT      L     + HR++IRQL  AG +IN    +TG TAL  A    +T++V LLLE
Sbjct: 990 YTPTMLASLAFIQNDDHRDIIRQLFLAG-DINACAEQTGQTALMLATSQCRTDMVELLLE 1166

Query: 243 GGVDVNIRNTYNQTAL 258
            G D N ++    TAL
Sbjct: 1167TGADCNQQDFDGSTAL 1214

 Score = 40.0 bits (92), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 28/92 (30%), Positives = 40/92 (43%), Gaps = 1/92 (1%)
 Frame = +3

Query: 82   GMRPLHYAAWQGRLEPVRLLLRASAAVNAASLDGQIPLHLAAQYGHYEVSEMLL-QHQSN 140
            G   L  A  Q R + V LLL   A  N    DG   L  A ++GH  + ++LL Q   +
Sbjct: 1101 GQTALMLATSQCRTDMVELLLETGADCNQQDFDGSTALMCACEHGHTAIVQLLLAQPHCD 1280

Query: 141  PCLVNKLKKTPLDLACEFGRLKVAQLLLNSHL 172
              L +    T L +A E     +  ++L  HL
Sbjct: 1281 ATLTDNENSTALSIAMEASHKDIG-VILYKHL 1373

 Score = 33.9 bits (76), Expect = 0.39,   Method: Compositional matrix adjust.
 Identities = 40/169 (23%), Positives = 59/169 (34%), Gaps = 39/169 (23%)
 Frame = +3

Query: 75   VDIKDSNGMRPLHYAAWQGRLEPVRLLLRASAA--------------------------- 107
            V++ DSNG   +HY       + V LLL                                
Sbjct: 864  VNLVDSNGNSAIHYCVSHCNFDIVGLLLDTEVCDVKRPNKAGYTPTMLASLAFIQNDDHR 1043

Query: 108  -----------VNA-ASLDGQIPLHLAAQYGHYEVSEMLLQHQSNPCLVNKLKKTPLDLA 155
                       +NA A   GQ  L LA      ++ E+LL+  ++    +    T L  A
Sbjct: 1044 DIIRQLFLAGDINACAEQTGQTALMLATSQCRTDMVELLLETGADCNQQDFDGSTALMCA 1223

Query: 156  CEFGRLKVAQLLLNSHLCVALLEGEAKDPCDPNYTTPLHLAAKNGHREV 204
            CE G   + QLLL    C A L        D   +T L +A +  H+++
Sbjct: 1224 CEHGHTAIVQLLLAQPHCDATLT-------DNENSTALSIAMEASHKDI 1349
>25464
          Length = 440

 Score = 48.9 bits (115), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 35/101 (34%), Positives = 49/101 (48%), Gaps = 5/101 (4%)
 Frame = -3

Query: 75  VDIKDSNGMRPLHYAAWQGRLEPVRLLLRASAA-VNAASLDGQIPLHLAAQYGHYEVSEM 133
           ++++DS G   L YA   GR + VR +L+     +N    DG  P+H AA   +  +  M
Sbjct: 432 LNVRDSMGRTALSYACLNGRQDIVRCILKEDVLDINEPDNDGNTPIHHAAISANPNIVRM 253

Query: 134 L----LQHQSNPCLVNKLKKTPLDLACEFGRLKVAQLLLNS 170
           L     +   NP   NKL  TPL LAC+ G    A  LL +
Sbjct: 252 LAEAFYKFGLNPDKRNKLGYTPLLLACKGGNYVSAYTLLTT 130
>05396
          Length = 1865

 Score = 45.4 bits (106), Expect = 1e-04,   Method: Composition-based stats.
 Identities = 27/89 (30%), Positives = 48/89 (53%), Gaps = 1/89 (1%)
 Frame = +3

Query: 80   SNGMRPLHYAAWQGRLEPVRLLLRASAAVNAASLDGQIPLHLAAQYGHYEVSEMLLQH-Q 138
            +N +  L ++A+ G +  +R    +   ++    DG+  LH+A+  G  +V E LL   +
Sbjct: 1278 ANRIVDLLFSAYNGDVTAIRRCALSGMDMSQPDYDGRTALHVASAEGQLQVVEFLLDRCK 1457

Query: 139  SNPCLVNKLKKTPLDLACEFGRLKVAQLL 167
             +P LV++   TPLD A  F + + A+LL
Sbjct: 1458 CSPFLVDRWGFTPLDDAVRFEKHEAAELL 1544
>28113
          Length = 449

 Score = 45.1 bits (105), Expect = 2e-04,   Method: Composition-based stats.
 Identities = 23/62 (37%), Positives = 37/62 (59%)
 Frame = -3

Query: 78  KDSNGMRPLHYAAWQGRLEPVRLLLRASAAVNAASLDGQIPLHLAAQYGHYEVSEMLLQH 137
           KDS     +HYA+W G  + V +LL A  + N  + +   PLH+AA+ G  +V+E L+Q 
Sbjct: 246 KDSIAWAAIHYASWYGSADVVEILLDAGCSPNLTNSELLTPLHIAAKKGFPDVAEHLVQA 67

Query: 138 QS 139
           ++
Sbjct: 66  EA 61

 Score = 41.2 bits (95), Expect = 0.003,   Method: Composition-based stats.
 Identities = 32/111 (28%), Positives = 50/111 (45%), Gaps = 6/111 (5%)
 Frame = -3

Query: 118 PLHLAAQYGHYEVSEMLLQHQSNPCLVNKLKKTPLDLACEFGRLKVAQLLLNSHLCVALL 177
           PLH +A  G     + LL H  +    + +    +  A  +G   V ++LL++       
Sbjct: 324 PLHASAAQGDVHHVQSLLNHGHHHSKKDSIAWAAIHYASWYGSADVVEILLDAG------ 163

Query: 178 EGEAKDPCDPNYT-----TPLHLAAKNGHREVIRQLLKA-GIEINRQTKTG 222
                  C PN T     TPLH+AAK G  +V   L++A  I++N + K G
Sbjct: 162 -------CSPNLTNSELLTPLHIAAKKGFPDVAEHLVQAEAIDLNLRDKDG 31

 Score = 40.8 bits (94), Expect = 0.004,   Method: Composition-based stats.
 Identities = 25/82 (30%), Positives = 42/82 (51%), Gaps = 3/82 (3%)
 Frame = -3

Query: 182 KDPCDPNYTT--PLHLAAKNGHREVIRQLLKAGIEINRQTKTG-TALHEAALYGKTEVVR 238
           ++P +P +    PLH +A  G    ++ LL  G   +++      A+H A+ YG  +VV 
Sbjct: 360 RNPVEPRWRDKYPLHASAAQGDVHHVQSLLNHGHHHSKKDSIAWAAIHYASWYGSADVVE 181

Query: 239 LLLEGGVDVNIRNTYNQTALDI 260
           +LL+ G   N+ N+   T L I
Sbjct: 180 ILLDAGCSPNLTNSELLTPLHI 115
>15359
          Length = 780

 Score = 44.7 bits (104), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 25/61 (40%), Positives = 38/61 (62%), Gaps = 2/61 (3%)
 Frame = +1

Query: 77  IKD-SNGMRPLHYAAWQGRLEPVRLLL-RASAAVNAASLDGQIPLHLAAQYGHYEVSEML 134
           +KD +NG   LH+AA  G+ E V++L  +    +N  S  G  PLHLAA +GH ++ E+L
Sbjct: 331 VKDIANGYTALHWAAKFGKPEVVKMLANKIGVEINQRSHGGYTPLHLAAIHGHEDIIELL 510

Query: 135 L 135
           +
Sbjct: 511 V 513

 Score = 33.5 bits (75), Expect = 0.48,   Method: Compositional matrix adjust.
 Identities = 21/60 (35%), Positives = 31/60 (51%)
 Frame = +1

Query: 150 TPLDLACEFGRLKVAQLLLNSHLCVALLEGEAKDPCDPNYTTPLHLAAKNGHREVIRQLL 209
           T L  A +FG+ +V ++L N       +  E        YT PLHLAA +GH ++I  L+
Sbjct: 355 TALHWAAKFGKPEVVKMLANK------IGVEINQRSHGGYT-PLHLAAIHGHEDIIELLV 513

 Score = 31.2 bits (69), Expect = 2.4,   Method: Compositional matrix adjust.
 Identities = 18/40 (45%), Positives = 25/40 (62%), Gaps = 1/40 (2%)
 Frame = +1

Query: 223 TALHEAALYGKTEVVRLLLEG-GVDVNIRNTYNQTALDIV 261
           TALH AA +GK EVV++L    GV++N R+    T L + 
Sbjct: 355 TALHWAAKFGKPEVVKMLANKIGVEINQRSHGGYTPLHLA 474
>38834
          Length = 496

 Score = 43.5 bits (101), Expect = 5e-04,   Method: Composition-based stats.
 Identities = 21/82 (25%), Positives = 42/82 (51%)
 Frame = -1

Query: 89  AAWQGRLEPVRLLLRASAAVNAASLDGQIPLHLAAQYGHYEVSEMLLQHQSNPCLVNKLK 148
           A   G L+   +L R    +N  +++G  P HL+  +  ++++  L++  +    VN   
Sbjct: 493 ACSSGHLDIAEMLHRRGVQINVVNINGYTPXHLSVYFNKFDITHFLVKINAEINTVNNAG 314

Query: 149 KTPLDLACEFGRLKVAQLLLNS 170
           +TP+ LA   G  K+  L++N+
Sbjct: 313 QTPVYLAALRGNSKILALMVNA 248

 Score = 38.1 bits (87), Expect = 0.022,   Method: Composition-based stats.
 Identities = 26/96 (27%), Positives = 47/96 (48%), Gaps = 1/96 (1%)
 Frame = -1

Query: 154 LACEFGRLKVAQLLLNSHLCVALLEGEAKDPCDPNYTTPLHLAAKNGHREVIRQLLKAGI 213
           +AC  G L +A++L    + + ++        + N  TP HL+      ++   L+K   
Sbjct: 496 IACSSGHLDIAEMLHRRGVQINVV--------NINGYTPXHLSVYFNKFDITHFLVKINA 341

Query: 214 EINRQTKTG-TALHEAALYGKTEVVRLLLEGGVDVN 248
           EIN     G T ++ AAL G ++++ L++  G  VN
Sbjct: 340 EINTVNNAGQTPVYLAALRGNSKILALMVNAGCKVN 233

 Score = 37.4 bits (85), Expect = 0.039,   Method: Composition-based stats.
 Identities = 22/96 (22%), Positives = 46/96 (47%)
 Frame = -1

Query: 121 LAAQYGHYEVSEMLLQHQSNPCLVNKLKKTPLDLACEFGRLKVAQLLLNSHLCVALLEGE 180
           +A   GH +++EML +      +VN    TP  L+  F +  +   L+  +  +  +   
Sbjct: 496 IACSSGHLDIAEMLHRRGVQINVVNINGYTPXHLSVYFNKFDITHFLVKINAEINTVNNA 317

Query: 181 AKDPCDPNYTTPLHLAAKNGHREVIRQLLKAGIEIN 216
            +        TP++LAA  G+ +++  ++ AG ++N
Sbjct: 316 GQ--------TPVYLAALRGNSKILALMVNAGCKVN 233

 Score = 37.0 bits (84), Expect = 0.042,   Method: Composition-based stats.
 Identities = 18/73 (24%), Positives = 40/73 (54%)
 Frame = -1

Query: 75  VDIKDSNGMRPLHYAAWQGRLEPVRLLLRASAAVNAASLDGQIPLHLAAQYGHYEVSEML 134
           +++ + NG  P H + +  + +    L++ +A +N  +  GQ P++LAA  G+ ++  ++
Sbjct: 436 INVVNINGYTPXHLSVYFNKFDITHFLVKINAEINTVNNAGQTPVYLAALRGNSKILALM 257

Query: 135 LQHQSNPCLVNKL 147
           +   +  C VN L
Sbjct: 256 V---NAGCKVNGL 227
>34789
          Length = 1249

 Score = 43.1 bits (100), Expect = 6e-04,   Method: Composition-based stats.
 Identities = 23/82 (28%), Positives = 43/82 (52%)
 Frame = +3

Query: 190 TTPLHLAAKNGHREVIRQLLKAGIEINRQTKTGTALHEAALYGKTEVVRLLLEGGVDVNI 249
           +T L +A  +G+ E++  LLK G   +  ++ G  LH A L     +++  L+ G D+N 
Sbjct: 81  STALFMAVYDGNVELVDYLLKNGANPHFSSQHGNFLHAAVLSQSVPLIQRALDLGCDINE 260

Query: 250 RNTYNQTALDIVNQFTTSQASR 271
            N +  + L +V++    +A R
Sbjct: 261 HNMFGNSPLTLVSRLDLPEACR 326
>17893
          Length = 453

 Score = 41.6 bits (96), Expect = 0.002,   Method: Composition-based stats.
 Identities = 23/59 (38%), Positives = 35/59 (59%), Gaps = 1/59 (1%)
 Frame = -3

Query: 203 EVIRQLLKAGIEINRQTKTG-TALHEAALYGKTEVVRLLLEGGVDVNIRNTYNQTALDI 260
           + +  LLK G  IN   +TG T LHEAA     +V R LL+ G++++  + Y +TAL +
Sbjct: 178 DFVDSLLKNGASINIMDRTGQTLLHEAARAWHVDVTRWLLDHGINIDQPDYYGRTALHV 2
>20884
          Length = 712

 Score = 40.8 bits (94), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 26/58 (44%), Positives = 33/58 (56%), Gaps = 3/58 (5%)
 Frame = +1

Query: 187 PN--YTTPLHLAAKNGHREVIRQLLKAGIEINRQTKTG-TALHEAALYGKTEVVRLLL 241
           PN  + TPLHLA       V+R+L+ AG  +      G TALH A   G TE+V+LLL
Sbjct: 286 PNMLHQTPLHLAVATRQMWVVRRLMVAGAAMEAPDYCGNTALHIACREGMTEMVKLLL 459

 Score = 33.1 bits (74), Expect = 0.60,   Method: Compositional matrix adjust.
 Identities = 27/94 (28%), Positives = 40/94 (42%), Gaps = 3/94 (3%)
 Frame = +1

Query: 45  QDADGFSALHHXXXXXXXXXXXXXXXXXXT---VDIKDSNGMRPLHYAAWQGRLEPVRLL 101
           QD DG S LH                   +   ++I +     PLH A    ++  VR L
Sbjct: 178 QDEDGDSYLHMSIIHLLPDVSLKVISVAPSPDYINIPNMLHQTPLHLAVATRQMWVVRRL 357

Query: 102 LRASAAVNAASLDGQIPLHLAAQYGHYEVSEMLL 135
           + A AA+ A    G   LH+A + G  E+ ++LL
Sbjct: 358 MVAGAAMEAPDYCGNTALHIACREGMTEMVKLLL 459

 Score = 32.3 bits (72), Expect = 1.0,   Method: Composition-based stats.
 Identities = 22/52 (42%), Positives = 29/52 (55%), Gaps = 2/52 (3%)
 Frame = +2

Query: 191 TPLHLAAKNGHREVIRQLLKAGIEINRQT-KTG-TALHEAALYGKTEVVRLL 240
           T  HLA + GH  ++  LL+ G  IN Q  K+G T LH AA  G  + + LL
Sbjct: 557 TCAHLALQTGHLHILPLLLERGANINEQDGKSGRTLLHMAADLGYLQALELL 712
>02055
          Length = 1740

 Score = 40.8 bits (94), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 42/149 (28%), Positives = 66/149 (44%), Gaps = 2/149 (1%)
 Frame = +3

Query: 75  VDIKDSNGMRPLHYAAWQGRLEPVRLLLRASAAVNA-ASLDGQIPLHLAAQY-GHYEVSE 132
           VD  +  G  PLH A      E +  L+R  A VNA A      PLH+A +  G  EV+ 
Sbjct: 402 VDFCNMFGDTPLHIATVHANHEAMGALVRNGANVNARAKFLNSTPLHVACRLRGQQEVA- 578

Query: 133 MLLQHQSNPCLVNKLKKTPLDLACEFGRLKVAQLLLNSHLCVALLEGEAKDPCDPNYTTP 192
           +L+Q  +   + +    TPL +AC+     V  +LL S   +   E       D N    
Sbjct: 579 LLIQLGARIDVNDATGTTPLQMACKRADPAVVNILLRSQPSIVRTE-------DANKLFK 737

Query: 193 LHLAAKNGHREVIRQLLKAGIEINRQTKT 221
             +  +  H  +++ L +AG+ +N +  T
Sbjct: 738 YAIQKRQLH--IVKMLCEAGVAVNYEGTT 818

 Score = 35.0 bits (79), Expect = 0.20,   Method: Compositional matrix adjust.
 Identities = 26/74 (35%), Positives = 38/74 (51%), Gaps = 4/74 (5%)
 Frame = +3

Query: 179 GEAKDPCDPNYTTPLHLAAKNGHREVIRQLLKAGIEINRQTK--TGTALHEAA-LYGKTE 235
           G   D C+    TPLH+A  + + E +  L++ G  +N + K    T LH A  L G+ E
Sbjct: 393 GADVDFCNMFGDTPLHIATVHANHEAMGALVRNGANVNARAKFLNSTPLHVACRLRGQQE 572

Query: 236 VVRLLLEGG-VDVN 248
           V  L+  G  +DVN
Sbjct: 573 VALLIQLGARIDVN 614
>28009
          Length = 370

 Score = 39.3 bits (90), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 15/41 (36%), Positives = 25/41 (60%), Gaps = 2/41 (4%)
 Frame = +2

Query: 479 VRPEQLLEGK--DAQAIHNWLSEFQLEGYTAHFLQAGYDVP 517
           +  +QL++    D + +H WL +   E Y  +F+QAGYD+P
Sbjct: 248 INVQQLMQAGVPDKEVLHAWLHDLHYEDYYTNFVQAGYDMP 370
>16561
          Length = 2029

 Score = 39.3 bits (90), Expect = 0.010,   Method: Compositional matrix adjust.
 Identities = 25/69 (36%), Positives = 35/69 (50%), Gaps = 1/69 (1%)
 Frame = -3

Query: 191  TPLHLAAKNGHREVIRQLLKAGIEINRQTKTGTA-LHEAALYGKTEVVRLLLEGGVDVNI 249
            T LH +A     +V++ LL  G +IN     G + LH A      + V +LL  G DVN 
Sbjct: 2006 TALHYSAFGNQPDVLQLLLSKGAKINALNNGGCSTLHVAVNKQHIKCVHVLLNXGCDVNX 1827

Query: 250  RNTYNQTAL 258
            ++ Y  TAL
Sbjct: 1826 QDAYGDTAL 1800

 Score = 35.8 bits (81), Expect = 0.12,   Method: Compositional matrix adjust.
 Identities = 21/61 (34%), Positives = 33/61 (54%)
 Frame = -3

Query: 76   DIKDSNGMRPLHYAAWQGRLEPVRLLLRASAAVNAASLDGQIPLHLAAQYGHYEVSEMLL 135
            DI+D  G   LHY+A+  + + ++LLL   A +NA +  G   LH+A    H +   +LL
Sbjct: 2024 DIRD--GDTALHYSAFGNQPDVLQLLLSKGAKINALNNGGCSTLHVAVNKQHIKCVHVLL 1851

Query: 136  Q 136
             
Sbjct: 1850 N 1848
>33144
          Length = 272

 Score = 38.1 bits (87), Expect = 0.019,   Method: Composition-based stats.
 Identities = 26/81 (32%), Positives = 39/81 (48%), Gaps = 1/81 (1%)
 Frame = +3

Query: 85  PLHYAAWQGRLEPVRLLLR-ASAAVNAASLDGQIPLHLAAQYGHYEVSEMLLQHQSNPCL 143
           PLH AA  GR     +L++    AVN      + PLH A Q     + ++LL   +NP +
Sbjct: 21  PLHLAAMNGRTAIAGVLVKKGEVAVNVVDKHKRTPLHYAVQTCELTIIDLLLGRDANPNI 200

Query: 144 VNKLKKTPLDLACEFGRLKVA 164
            +    TP  LA +  +L +A
Sbjct: 201 QDVDGNTPTHLA-QMAKLPIA 260

 Score = 35.0 bits (79), Expect = 0.20,   Method: Composition-based stats.
 Identities = 19/48 (39%), Positives = 24/48 (50%)
 Frame = +3

Query: 75  VDIKDSNGMRPLHYAAWQGRLEPVRLLLRASAAVNAASLDGQIPLHLA 122
           V++ D +   PLHYA     L  + LLL   A  N   +DG  P HLA
Sbjct: 93  VNVVDKHKRTPLHYAVQTCELTIIDLLLGRDANPNIQDVDGNTPTHLA 236

 Score = 31.6 bits (70), Expect = 2.2,   Method: Composition-based stats.
 Identities = 27/82 (32%), Positives = 40/82 (48%), Gaps = 3/82 (3%)
 Frame = +3

Query: 118 PLHLAAQYGHYEVSEMLLQH-QSNPCLVNKLKKTPLDLACEFGRLKVAQLLLNSHLCVAL 176
           PLHLAA  G   ++ +L++  +    +V+K K+TPL  A +   L +  LLL        
Sbjct: 21  PLHLAAMNGRTAIAGVLVKKGEVAVNVVDKHKRTPLHYAVQTCELTIIDLLL-------- 176

Query: 177 LEGEAKDPC--DPNYTTPLHLA 196
             G   +P   D +  TP HLA
Sbjct: 177 --GRDANPNIQDVDGNTPTHLA 236
>28494
          Length = 463

 Score = 38.1 bits (87), Expect = 0.024,   Method: Composition-based stats.
 Identities = 27/85 (31%), Positives = 43/85 (50%), Gaps = 1/85 (1%)
 Frame = -1

Query: 196 AAKNGHREVIRQLLKAGIEINRQTKTG-TALHEAALYGKTEVVRLLLEGGVDVNIRNTYN 254
           A  +G R+ +++LL+ G +IN     G TALH+A +    ++V  L+E   DV++ +   
Sbjct: 298 ACSSGDRDEVKKLLERGADINTANVDGLTALHQACIDDNLDMVEFLVEQNADVDVCDNEG 119

Query: 255 QTALDIVNQFTTSQASREIKQLLRE 279
            T L      T S    EI + L E
Sbjct: 118 WTPL----HATASCGFTEIARYLLE 56

 Score = 33.9 bits (76), Expect = 0.42,   Method: Composition-based stats.
 Identities = 22/82 (26%), Positives = 40/82 (48%)
 Frame = -1

Query: 89  AAWQGRLEPVRLLLRASAAVNAASLDGQIPLHLAAQYGHYEVSEMLLQHQSNPCLVNKLK 148
           A   G  + V+ LL   A +N A++DG   LH A    + ++ E L++  ++  + +   
Sbjct: 298 ACSSGDRDEVKKLLERGADINTANVDGLTALHQACIDDNLDMVEFLVEQNADVDVCDNEG 119

Query: 149 KTPLDLACEFGRLKVAQLLLNS 170
            TPL      G  ++A+ LL +
Sbjct: 118 WTPLHATASCGFTEIARYLLEN 53

 Score = 33.5 bits (75), Expect = 0.60,   Method: Composition-based stats.
 Identities = 21/66 (31%), Positives = 26/66 (39%)
 Frame = -1

Query: 41  NINYQDADGFSALHHXXXXXXXXXXXXXXXXXXTVDIKDSNGMRPLHYAAWQGRLEPVRL 100
           +IN  + DG +ALH                    VD+ D+ G  PLH  A  G  E  R 
Sbjct: 244 DINTANVDGLTALHQACIDDNLDMVEFLVEQNADVDVCDNEGWTPLHATASCGFTEIARY 65

Query: 101 LLRASA 106
           LL   A
Sbjct: 64  LLENGA 47

 Score = 29.6 bits (65), Expect = 7.6,   Method: Composition-based stats.
 Identities = 19/61 (31%), Positives = 31/61 (50%), Gaps = 1/61 (1%)
 Frame = -1

Query: 191 TPLHLAAKNGHREVIRQLLKAGIEINRQTKTG-TALHEAALYGKTEVVRLLLEGGVDVNI 249
           T LH A  + + +++  L++   +++     G T LH  A  G TE+ R LLE G +   
Sbjct: 214 TALHQACIDDNLDMVEFLVEQNADVDVCDNEGWTPLHATASCGFTEIARYLLENGANGGC 35

Query: 250 R 250
           R
Sbjct: 34  R 32
>30217
          Length = 412

 Score = 37.7 bits (86), Expect = 0.029,   Method: Compositional matrix adjust.
 Identities = 21/58 (36%), Positives = 33/58 (56%), Gaps = 3/58 (5%)
 Frame = -3

Query: 114 DGQIPLHLAAQYGHYEVSEMLLQHQSNPCLV---NKLKKTPLDLACEFGRLKVAQLLL 168
           DG  PLHLA   G+ +V   L++   +PCL+   N + +TPL LA    +  + ++LL
Sbjct: 209 DGDTPLHLACISGYVDVVAALIRMAPHPCLLNIQNDVAQTPLHLAALTAQPTILRMLL 36

 Score = 35.4 bits (80), Expect = 0.14,   Method: Compositional matrix adjust.
 Identities = 24/68 (35%), Positives = 32/68 (47%), Gaps = 2/68 (2%)
 Frame = -3

Query: 149 KTPLDLACEFGRLKVAQLLLNS--HLCVALLEGEAKDPCDPNYTTPLHLAAKNGHREVIR 206
            TPL LAC  G + V   L+    H C+  ++ +          TPLHLAA      ++R
Sbjct: 203 DTPLHLACISGYVDVVAALIRMAPHPCLLNIQNDVAQ-------TPLHLAALTAQPTILR 45

Query: 207 QLLKAGIE 214
            LL AG E
Sbjct: 44  MLLLAGAE 21

 Score = 30.8 bits (68), Expect = 3.5,   Method: Compositional matrix adjust.
 Identities = 20/61 (32%), Positives = 30/61 (49%), Gaps = 3/61 (4%)
 Frame = -3

Query: 78  KDSNGMRPLHYAAWQGRLEPVRLLLRAS---AAVNAASLDGQIPLHLAAQYGHYEVSEML 134
           ++ +G  PLH A   G ++ V  L+R +     +N  +   Q PLHLAA      +  ML
Sbjct: 218 QNDDGDTPLHLACISGYVDVVAALIRMAPHPCLLNIQNDVAQTPLHLAALTAQPTILRML 39

Query: 135 L 135
           L
Sbjct: 38  L 36
>17286
          Length = 489

 Score = 35.8 bits (81), Expect = 0.095,   Method: Compositional matrix adjust.
 Identities = 24/72 (33%), Positives = 39/72 (54%)
 Frame = +3

Query: 287 RALKDFWNLHDPTALNVRAGDVITVLEQHPDGRWKGHIHESQRGTDRVGYFPPGIVEVVS 346
           RA+ DF    D   L  + GD+IT++ Q  +  ++G +H       +VGYFP   VEVV 
Sbjct: 33  RAIYDFLPESD-GELGFQEGDMITLISQVDENWFEGSVH------GKVGYFPINYVEVV- 188

Query: 347 KRVGIPVARLPS 358
               +P++ +P+
Sbjct: 189 ----VPIS*VPA 212
>20121
          Length = 454

 Score = 35.8 bits (81), Expect = 0.098,   Method: Compositional matrix adjust.
 Identities = 22/58 (37%), Positives = 30/58 (51%), Gaps = 1/58 (1%)
 Frame = -1

Query: 186 DPNYTTPLHLAAKNGHREVIRQLLKAGIEINRQTK-TGTALHEAALYGKTEVVRLLLE 242
           DP   T LHL+   GH E  R LL+ G E   +     + LHE    G  E+V+L+L+
Sbjct: 259 DPRGRTALHLSVSLGHLESTRVLLRHGAEAGTENNGCWSVLHEGVCSGDPELVQLILQ 86

 Score = 32.0 bits (71), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 16/54 (29%), Positives = 25/54 (46%), Gaps = 1/54 (1%)
 Frame = -1

Query: 85  PLHYAAWQGRLEPV-RLLLRASAAVNAASLDGQIPLHLAAQYGHYEVSEMLLQH 137
           P+H+  W      + RLL      +      G+  LHL+   GH E + +LL+H
Sbjct: 343 PIHWLTWHNNFRELDRLLGLKEHDIETKDPRGRTALHLSVSLGHLESTRVLLRH 182
>27252
          Length = 378

 Score = 34.7 bits (78), Expect = 0.24,   Method: Compositional matrix adjust.
 Identities = 19/52 (36%), Positives = 29/52 (55%)
 Frame = +2

Query: 296 HDPTALNVRAGDVITVLEQHPDGRWKGHIHESQRGTDRVGYFPPGIVEVVSK 347
           +D T L ++ G+ I VL  + DG+W+G I+       R G FP   VE +S+
Sbjct: 158 YDRTQLKLKQGETIKVLAINIDGQWEGEIN------GRTGKFPFTHVEFLSE 295
>35952
          Length = 1624

 Score = 34.3 bits (77), Expect = 0.30,   Method: Compositional matrix adjust.
 Identities = 25/65 (38%), Positives = 34/65 (52%), Gaps = 3/65 (4%)
 Frame = -1

Query: 74   TVDIKD-SNGMRPLHYAAWQGRLEPVR--LLLRASAAVNAASLDGQIPLHLAAQYGHYEV 130
             VD+ D  +G   LH+A     L PV   LL+ A+A VNA   DG  PLH+A   G   +
Sbjct: 1000 NVDLPDGKSGRTALHHAVELDDL-PVAGFLLMEANADVNARCFDGNTPLHVACCRGLIGM 824

Query: 131  SEMLL 135
              +L+
Sbjct: 823  VALLM 809
>07218
          Length = 1715

 Score = 33.9 bits (76), Expect = 0.44,   Method: Composition-based stats.
 Identities = 18/53 (33%), Positives = 25/53 (47%)
 Frame = +1

Query: 496 WLSEFQLEGYTAHFLQAGYDVPTISRMTPEDLTAIGVTKPGHRKKIASEIAQL 548
           WL    L  Y A+F+        +  +   DL  +GVTK GH K+I   I +L
Sbjct: 223 WLESLSLGEYRANFISHEIRGAELLSLERRDLKDLGVTKVGHLKRIQQAIKEL 381
>26032
          Length = 465

 Score = 33.5 bits (75), Expect = 0.47,   Method: Composition-based stats.
 Identities = 17/53 (32%), Positives = 27/53 (50%)
 Frame = +2

Query: 296 HDPTALNVRAGDVITVLEQHPDGRWKGHIHESQRGTDRVGYFPPGIVEVVSKR 348
           HD   L  R  D+IT++ Q  +  W G ++  +      G+FP   VEV+ +R
Sbjct: 41  HDDDELGFRKNDIITLISQKDEHCWIGELNGLR------GWFPAKFVEVLDER 181
>15772
          Length = 1282

 Score = 33.1 bits (74), Expect = 0.69,   Method: Composition-based stats.
 Identities = 19/62 (30%), Positives = 28/62 (45%)
 Frame = -3

Query: 78   KDSNGMRPLHYAAWQGRLEPVRLLLRASAAVNAASLDGQIPLHLAAQYGHYEVSEMLLQH 137
            +   G  P H AA   R+  +R L  A   V+     G  P  +A  YGH + +  LLQ 
Sbjct: 1091 RTDTGWTPAHCAAECNRVTALRALHAALVPVDLTDKYGDTPRRIATLYGHRDCARYLLQA 912

Query: 138  QS 139
            ++
Sbjct: 911  EA 906

 Score = 31.2 bits (69), Expect = 2.7,   Method: Composition-based stats.
 Identities = 22/62 (35%), Positives = 31/62 (50%), Gaps = 4/62 (6%)
 Frame = -3

Query: 193  LHLAAKNGHREVIRQLLKAGI-EINRQTKTG---TALHEAALYGKTEVVRLLLEGGVDVN 248
            LH AA  G  + +   +K+GI ++N +       TALH A   G  E +RLLL+ G    
Sbjct: 1274 LHDAASTGDYDALEDYVKSGIYDVNLKDPDAGNKTALHWACQKGFVECIRLLLDHGAKGT 1095

Query: 249  IR 250
             R
Sbjct: 1094 AR 1089
>21751
          Length = 643

 Score = 31.2 bits (69), Expect = 2.6,   Method: Composition-based stats.
 Identities = 28/91 (30%), Positives = 48/91 (52%), Gaps = 4/91 (4%)
 Frame = +3

Query: 131 SEMLLQHQSNPCLVNKLKKTPLD--LACEFGRLKVAQLLLNSHLCVALLE-GE-AKDPCD 186
           S +L+Q+ ++   V++L+   LD  +      L VA L  N HL   LLE GE      +
Sbjct: 3   SNLLIQYGAD---VHQLRTVSLDDKVFTSQSPLHVAILRKNVHLGRLLLEHGEDVNQTFN 173

Query: 187 PNYTTPLHLAAKNGHREVIRQLLKAGIEINR 217
            +  +P+H A +N   ++I  L++ G ++NR
Sbjct: 174 DSLESPIHQAVRNLDLDMINLLIEFGADLNR 266

 Score = 29.6 bits (65), Expect = 8.4,   Method: Composition-based stats.
 Identities = 18/63 (28%), Positives = 34/63 (53%), Gaps = 2/63 (3%)
 Frame = +3

Query: 191 TPLHLAAKNGHREVIRQLLKAGIEINRQTKTG--TALHEAALYGKTEVVRLLLEGGVDVN 248
           +PLH+A    +  + R LL+ G ++N+       + +H+A      +++ LL+E G D+N
Sbjct: 84  SPLHVAILRKNVHLGRLLLEHGEDVNQTFNDSLESPIHQAVRNLDLDMINLLIEFGADLN 263

Query: 249 IRN 251
             N
Sbjct: 264 RPN 272
>21532
          Length = 460

 Score = 30.0 bits (66), Expect = 5.4,   Method: Compositional matrix adjust.
 Identities = 30/119 (25%), Positives = 49/119 (41%), Gaps = 8/119 (6%)
 Frame = -1

Query: 130 VSEMLLQHQSNPCLVNKLKKTPLDLACEFGRLKVAQLLLNSHLCVALLEGEAKDPCDP-- 187
           +   LL H ++  + +    TP   AC  G L   + LL          GE+     P  
Sbjct: 451 IINTLLSHGADVNIRDNTGCTPFANACCLGNLAAVKALLTP--------GESPSWSKPMI 296

Query: 188 -----NYTTPLHLAAKNGHREVIRQLLKAGIEINRQTKTG-TALHEAALYGKTEVVRLL 240
                +  TPLHLA++ GH  ++  L++   ++  +  +G   L  A  Y    VV +L
Sbjct: 295 NVRDNSQNTPLHLASQEGHTAIVELLVEHKADLAAKNDSGHNPLSLARQYKHENVVAVL 119
>22305
          Length = 426

 Score = 30.0 bits (66), Expect = 6.4,   Method: Compositional matrix adjust.
 Identities = 18/63 (28%), Positives = 32/63 (50%)
 Frame = -3

Query: 101 LLRASAAVNAASLDGQIPLHLAAQYGHYEVSEMLLQHQSNPCLVNKLKKTPLDLACEFGR 160
           LL    + N  +  G +PLH A  + + EV  +LLQ+ ++P +  +    PL  A   G 
Sbjct: 328 LLERGCSANERNHWGILPLHEALCWENVEVGRVLLQYGADPNVPCETNVVPLTFAARTGH 149

Query: 161 LKV 163
           +++
Sbjct: 148 IRL 140
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|157816993|ref|NP_033864.2| pre-acrosome localization
protein 1 isoform 1 [Mus musculus]
         (1060 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

26033                                                                  80   4e-15
09060                                                                  53   7e-07
05977                                                                  37   0.037
15478                                                                  31   3.2  
34454                                                                  30   6.4  
22811                                                                  29   9.0  
>26033
          Length = 475

 Score = 80.1 bits (196), Expect = 4e-15,   Method: Compositional matrix adjust.
 Identities = 50/149 (33%), Positives = 75/149 (50%)
 Frame = -3

Query: 774 YNEVAEEKERLGXXXXXXXXXXXXXXXXXXXSSAALTRALXXXXXXXXXXXXXXHQMELK 833
           YNE+ +EK+R                     S      A+              H  E +
Sbjct: 449 YNEIQDEKDRXSSNASRQRQELDALRRQLEDSHRLALSAMKEQFEKAKEEQDRRHATESR 270

Query: 834 ALKDQLEAERQAWVASCAKKEEAWLLTRERELKEEIRKGRDQEIELVIHRLEADMTLAKX 893
            L+++L+ E++AW  +  KK + WL+ +ERELKE++RK RD+EIE VI RLE D  +A+ 
Sbjct: 269 ELQERLQLEKEAWEENYRKKHDTWLVQKERELKEQVRKERDKEIEAVITRLEEDSCVARE 90

Query: 894 XXXXXXXXXVKRVRDKYETELSELEQSER 922
                    ++R+R+K+E E  ELE SER
Sbjct: 89  EGDKVTETKLRRLREKFEAETKELEDSER 3
>09060
          Length = 1833

 Score = 52.8 bits (125), Expect = 7e-07,   Method: Compositional matrix adjust.
 Identities = 46/168 (27%), Positives = 79/168 (47%), Gaps = 34/168 (20%)
 Frame = +3

Query: 467  KDRYAWTD------EEEDANSLTADNLEKFGKLSAAPGPPDDGTLLSEAKLQSIMTFLDE 520
            +++ +W D      +E+D ++LTA+NLEK   L+A+        +L++ KL+SIM+FLDE
Sbjct: 1308 REKMSWLDNLEKDQDEDDGSNLTAENLEK---LNASKDGLSKSGMLTDDKLKSIMSFLDE 1478

Query: 521  MEKSGQ---------------ERPAPWRESLVLEAGSG-------------SEGSTSVMR 552
            ++ S +               E+PA          GSG             SE + +V+ 
Sbjct: 1479 VQVSDRLSEIDTEIHRMNEELEKPAVL-------VGSGEEVAQMEKAQAVASEVTNTVLT 1637

Query: 553  LKLELEEKKXXXXXXXXXXXXXXXXTVRRVKETEKELTRQLRQQKEQY 600
             +LEL+EK                 TVR  +E ++E+ ++L  QK++ 
Sbjct: 1638 QRLELDEKARTVTMLQKALNQQRELTVRHAREADREMKKRLDVQKDEI 1781

 Score = 38.1 bits (87), Expect = 0.021,   Method: Compositional matrix adjust.
 Identities = 15/37 (40%), Positives = 24/37 (64%)
 Frame = +3

Query: 258 FIHQVNQAAVTIQRWYRCQVQRRRAGAAALEHLLASK 294
           ++  +N +A  IQRWYR  ++R++ G AA+  LL  K
Sbjct: 663 YLLILNSSATKIQRWYRRHIKRKQVGQAAMRRLLQQK 773
>05977
          Length = 740

 Score = 37.0 bits (84), Expect = 0.037,   Method: Compositional matrix adjust.
 Identities = 15/37 (40%), Positives = 24/37 (64%)
 Frame = +3

Query: 258 FIHQVNQAAVTIQRWYRCQVQRRRAGAAALEHLLASK 294
           ++  +N +A  IQRWYR  ++R++ G AA+  LL  K
Sbjct: 207 YLLILNSSATKIQRWYRRHIKRKQVGQAAMRRLLQQK 317
>15478
          Length = 1282

 Score = 30.8 bits (68), Expect = 3.2,   Method: Compositional matrix adjust.
 Identities = 16/43 (37%), Positives = 29/43 (67%)
 Frame = +1

Query: 913 ELSELEQSERKLQERCSELKGRLGEAEGEKERLQSLVRQKEKE 955
           EL E+++  +  QER  E+KG++GE +   E++  L RQ+++E
Sbjct: 601 ELVEMQEVIKATQERMEEIKGKIGELD---EKIAELTRQRDEE 720
>34454
          Length = 1022

 Score = 29.6 bits (65), Expect = 6.4,   Method: Compositional matrix adjust.
 Identities = 14/40 (35%), Positives = 23/40 (57%)
 Frame = -2

Query: 609 SFIDQLIEDKKVLSEKCEAVVAELKHGDQRCRERVAQMQE 648
           +F++QLI DK  L E  +  + EL    ++C+E   Q+ E
Sbjct: 877 AFLEQLIMDKMTLEESVQEKIQELSQALEQCKELQIQLDE 758
>22811
          Length = 780

 Score = 29.3 bits (64), Expect = 9.0,   Method: Compositional matrix adjust.
 Identities = 14/27 (51%), Positives = 21/27 (77%)
 Frame = -2

Query: 933 GRLGEAEGEKERLQSLVRQKEKELEDL 959
           GR+ EAE EK RL++L R++ K+ E+L
Sbjct: 461 GRIQEAESEKNRLENLQRERRKKTEEL 381
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|148238335|ref|NP_062357.3| RNA and export factor
binding protein 2 [Mus musculus]
         (218 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

23225                                                                  77   5e-15
30672                                                                  46   1e-05
00302                                                                  44   5e-05
01278                                                                  44   7e-05
08958                                                                  43   8e-05
13822                                                                  43   9e-05
02064                                                                  40   7e-04
08816                                                                  39   0.001
03059                                                                  39   0.002
17775                                                                  38   0.002
28652                                                                  32   0.17 
03406                                                                  31   0.37 
26197                                                                  30   1.1  
31265                                                                  29   1.2  
37645                                                                  28   2.8  
>23225
          Length = 1278

 Score = 77.0 bits (188), Expect = 5e-15,   Method: Compositional matrix adjust.
 Identities = 36/49 (73%), Positives = 41/49 (83%)
 Frame = +2

Query: 102 KKAAVDYDRSGRSLGTADVHFERRADALKAMKQYKGVPLDGRPMDIQLV 150
           ++AAV YDRSGRSLGTA+V + RR DA+KAMKQY  VPLDGR M IQLV
Sbjct: 464 EQAAVHYDRSGRSLGTAEVIYVRRTDAVKAMKQYNNVPLDGRAMSIQLV 610

 Score = 59.7 bits (143), Expect = 9e-10,   Method: Compositional matrix adjust.
 Identities = 35/85 (41%), Positives = 42/85 (49%), Gaps = 19/85 (22%)
 Frame = +1

Query: 46  YSRPKPLPDKWQHDLFDSX-----------XXXXXXXXXXAKLLVSNLDFGVSDADIQEL 94
           Y RPK LPD WQHD+FD                        KLLVSNLDFGV+D+DIQEL
Sbjct: 265 YQRPKELPDVWQHDMFDGSDGGYRRGPGPMRSASGVASTSGKLLVSNLDFGVNDSDIQEL 444

Query: 95  FAEF------GTLK--KAAVDYDRS 111
                     G+L+  +  + Y RS
Sbjct: 445 LQSLVS*TSSGSLRQVRKVIGYRRS 519

 Score = 26.9 bits (58), Expect = 6.3,   Method: Compositional matrix adjust.
 Identities = 11/15 (73%), Positives = 14/15 (93%)
 Frame = +2

Query: 200 SAEELDAQLDAYNAR 214
           S EEL+AQLDAYN++
Sbjct: 818 SLEELNAQLDAYNSK 862
>30672
          Length = 877

 Score = 46.2 bits (108), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 23/73 (31%), Positives = 37/73 (50%)
 Frame = +3

Query: 75  AKLLVSNLDFGVSDADIQELFAEFGTLKKAAVDYDRSGRSLGTADVHFERRADALKAMKQ 134
            +L++ NL F   +ADI+  F +FGT+ +  +   +  RS G A V F     A KA+  
Sbjct: 405 CRLIIRNLAFKCKEADIRSHFGKFGTISEVTIPLKQGDRSRGFAFVQFTEVKAAQKAISD 584

Query: 135 YKGVPLDGRPMDI 147
             G  +  RP+ +
Sbjct: 585 MNGTAIMDRPVAV 623
>00302
          Length = 927

 Score = 43.9 bits (102), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 23/78 (29%), Positives = 42/78 (53%), Gaps = 1/78 (1%)
 Frame = -1

Query: 77  LLVSNLDFGVSDADIQELFAEFGTLKKAAVDYDR-SGRSLGTADVHFERRADALKAMKQY 135
           L +  L     +  ++E+F  +G + +  V YDR +GRS G A V+F+   DA +A  + 
Sbjct: 459 LGIFGLSLYTQERGLREVFGRYGHISEVQVVYDRQTGRSRGFAFVYFKSSEDAHEAKDRC 280

Query: 136 KGVPLDGRPMDIQLVTSQ 153
            G+ +DGR + +    ++
Sbjct: 279 NGIEIDGRKIRVDFSITE 226
>01278
          Length = 1082

 Score = 43.5 bits (101), Expect = 7e-05,   Method: Compositional matrix adjust.
 Identities = 24/68 (35%), Positives = 39/68 (57%), Gaps = 1/68 (1%)
 Frame = +2

Query: 75  AKLLVSNLDFGVSDADIQELFAEFGTLKKAAVDYDR-SGRSLGTADVHFERRADALKAMK 133
           A + V+NL     ++D+QELF  FG + +  +  D+ +G+S G A ++F RR DA +A+ 
Sbjct: 635 ATIRVTNLSEDTRESDLQELFRPFGPISRIYLAKDKVTGQSKGFAFINFHRREDASRAIA 814

Query: 134 QYKGVPLD 141
              G   D
Sbjct: 815 GVSGFGYD 838
>08958
          Length = 680

 Score = 43.1 bits (100), Expect = 8e-05,   Method: Compositional matrix adjust.
 Identities = 28/78 (35%), Positives = 46/78 (58%), Gaps = 4/78 (5%)
 Frame = +2

Query: 75  AKLLVSNLDFGVSDADIQELFAEFGTLKKAAVDYDRSGRSLGTADVHFERRADALKAMKQ 134
           A L V NL   VS+  +++ F +FG L++A V  D  GRS G   V F R+  A +A+++
Sbjct: 290 AALKVKNLHPYVSNELLEQAFTQFGDLERAIVIVDERGRSTGEGVVEFVRKPGAQQALRR 469

Query: 135 Y-KGVPLDG---RPMDIQ 148
             +GV L G   +P++++
Sbjct: 470 INEGVFLFGADPKPIEVE 523
>13822
          Length = 963

 Score = 43.1 bits (100), Expect = 9e-05,   Method: Compositional matrix adjust.
 Identities = 23/79 (29%), Positives = 44/79 (55%)
 Frame = -1

Query: 76  KLLVSNLDFGVSDADIQELFAEFGTLKKAAVDYDRSGRSLGTADVHFERRADALKAMKQY 135
           +L VSN+ F   +AD+++L   FGT+    + ++  G S G   V F   A+A +A  + 
Sbjct: 339 RLHVSNIPFRFREADLRQLLGPFGTILDVEIIFNERG-SKGFGFVTFAHSAEAERARDKM 163

Query: 136 KGVPLDGRPMDIQLVTSQI 154
            G  ++GR +++   T+++
Sbjct: 162 NGTVVEGRKIEVNNATARV 106
>02064
          Length = 1195

 Score = 40.0 bits (92), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 21/75 (28%), Positives = 39/75 (52%)
 Frame = +1

Query: 75  AKLLVSNLDFGVSDADIQELFAEFGTLKKAAVDYDRSGRSLGTADVHFERRADALKAMKQ 134
             + V NL + ++  D++E F E G +K + +  D+ GRS G   V F    DA++A+  
Sbjct: 79  CTVQVKNLPYAITWQDLRERFQEIGVVKYSEITMDK-GRSTGQGLVRFATEDDAVRAINS 255

Query: 135 YKGVPLDGRPMDIQL 149
                 +GR + +++
Sbjct: 256 MDRTRYEGRTIGVKM 300
>08816
          Length = 566

 Score = 39.3 bits (90), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 23/75 (30%), Positives = 41/75 (54%)
 Frame = +1

Query: 75  AKLLVSNLDFGVSDADIQELFAEFGTLKKAAVDYDRSGRSLGTADVHFERRADALKAMKQ 134
             + V N+ F ++  +++E F + G +K + +  D+ GR  G A V F   ADA++A+  
Sbjct: 49  CTVTVRNVPFSLTWQELRERFQDIGDVKFSEILMDQ-GRPSGDAVVRFGTSADAMRAINL 225

Query: 135 YKGVPLDGRPMDIQL 149
             G  +DGR + + L
Sbjct: 226 VDGTRIDGRTVRVVL 270
>03059
          Length = 1154

 Score = 38.5 bits (88), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 26/71 (36%), Positives = 37/71 (52%), Gaps = 2/71 (2%)
 Frame = -2

Query: 75  AKLLVSNLDFGVSDADIQELFAEFGTLKKAAVDYDR--SGRSLGTADVHFERRADALKAM 132
            K+ V  L   V+   IQE+F+ +GT+K   +  DR     S G A V +E   DA KA+
Sbjct: 670 TKVHVGRLTRNVNKDHIQEIFSLYGTIKFIDLPNDRIHPNTSKGHAYVEYENPEDAEKAV 491

Query: 133 KQYKGVPLDGR 143
           K   G  +DG+
Sbjct: 490 KYMDGGQIDGQ 458
>17775
          Length = 1282

 Score = 38.1 bits (87), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 23/73 (31%), Positives = 38/73 (52%)
 Frame = -2

Query: 77  LLVSNLDFGVSDADIQELFAEFGTLKKAAVDYDRSGRSLGTADVHFERRADALKAMKQYK 136
           L V NLD  + D  +++ F+ FGT+  A +  +  GRS G   V F    +A KA+ +  
Sbjct: 336 LYVKNLDDSIDDERLRKEFSNFGTITSAKIMTE-GGRSKGFGFVCFSSPEEATKAVTEMN 160

Query: 137 GVPLDGRPMDIQL 149
           G  +  +P+ + L
Sbjct: 159 GRIIVAKPLYVAL 121

 Score = 36.2 bits (82), Expect = 0.010,   Method: Compositional matrix adjust.
 Identities = 31/86 (36%), Positives = 47/86 (54%), Gaps = 1/86 (1%)
 Frame = -2

Query: 75   AKLLVSNLDFGVSDADIQELFAEFGTLKKAAVDYDR-SGRSLGTADVHFERRADALKAMK 133
            A L V +L   V++A + E F+  G +    V  D  + RSLG A V+F++ ADA +A+ 
Sbjct: 1194 ASLYVGDLHPDVTEAMLFEKFSTAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALD 1015

Query: 134  QYKGVPLDGRPMDIQLVTSQIDPQRR 159
                  + GRP  I+++ SQ DP  R
Sbjct: 1014 TMNFDTVKGRP--IRIMWSQRDPSVR 943
>28652
          Length = 918

 Score = 32.0 bits (71), Expect = 0.17,   Method: Compositional matrix adjust.
 Identities = 23/73 (31%), Positives = 35/73 (47%), Gaps = 2/73 (2%)
 Frame = -2

Query: 77  LLVSNLDFGVSDADIQELFAEFGTLK--KAAVDYDRSGRSLGTADVHFERRADALKAMKQ 134
           L V NL   V++ D++E F  +G ++  K   DY           VH+E R DALKA+  
Sbjct: 194 LYVRNLTGDVTEDDLKEKFGAYGKVERVKKIKDY---------GFVHYEDREDALKALDD 42

Query: 135 YKGVPLDGRPMDI 147
             G  +    +D+
Sbjct: 41  LHGEKIGNLEIDV 3
>03406
          Length = 1292

 Score = 31.2 bits (69), Expect = 0.37,   Method: Compositional matrix adjust.
 Identities = 13/35 (37%), Positives = 20/35 (57%)
 Frame = +3

Query: 76  KLLVSNLDFGVSDADIQELFAEFGTLKKAAVDYDR 110
           K+ V  LD GV   D++  FA+FG +    + YD+
Sbjct: 489 KIFVGKLDPGVPQEDVESYFAKFGKVVNVELPYDK 593
>26197
          Length = 1365

 Score = 29.6 bits (65), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 12/36 (33%), Positives = 19/36 (52%)
 Frame = -3

Query: 75   AKLLVSNLDFGVSDADIQELFAEFGTLKKAAVDYDR 110
             +  V  LD GV   D++  FA+FG +    + YD+
Sbjct: 1051 GRFFVGKLDPGVPQEDVESYFAKFGKVVNVELPYDK 944
>31265
          Length = 540

 Score = 29.3 bits (64), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 19/73 (26%), Positives = 35/73 (47%)
 Frame = +2

Query: 77  LLVSNLDFGVSDADIQELFAEFGTLKKAAVDYDRSGRSLGTADVHFERRADALKAMKQYK 136
           L V NL    ++  ++++F+          + +R  +    A VHF  R DA+KAM    
Sbjct: 164 LXVRNLMLTTTEETLKDVFSR----AAGGREIERVKKIRDYAFVHFRSREDAIKAMDVTD 331

Query: 137 GVPLDGRPMDIQL 149
           G  ++G  +++ L
Sbjct: 332 GSTIEGSQVEVVL 370
>37645
          Length = 1070

 Score = 28.1 bits (61), Expect = 2.8,   Method: Compositional matrix adjust.
 Identities = 12/38 (31%), Positives = 21/38 (55%)
 Frame = -2

Query: 112 GRSLGTADVHFERRADALKAMKQYKGVPLDGRPMDIQL 149
           GRS+G   V F    DA++A+        +GR +D+++
Sbjct: 970 GRSMGQGLVRFATEDDAVRAINSMDRTRFEGRTIDVKM 857
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|170784834|ref|NP_031970.2| epidermal growth factor
receptor pathway substrate 15, related isoform a [Mus musculus]
         (907 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

01130                                                                  80   5e-15
19303                                                                  73   4e-13
37000                                                                  73   6e-13
19700                                                                  38   0.022
30643                                                                  30   3.2  
14714                                                                  30   5.8  
>01130
          Length = 1032

 Score = 79.7 bits (195), Expect = 5e-15,   Method: Compositional matrix adjust.
 Identities = 59/175 (33%), Positives = 85/175 (48%), Gaps = 1/175 (0%)
 Frame = +3

Query: 18  LYESYYKQVDPAYTGRVGASEAALFLKKSGLSDIILGKIWDLADPEGKGFLDKQGFYVAL 77
           LYE  +    P     +G     LFLK SGLS  +L +IW+LAD      L+   F + +
Sbjct: 240 LYELLFYSQGPVDGYILGEGVRDLFLK-SGLSLRVLSQIWNLADVSNDNVLNVHEFSLVM 416

Query: 78  RLVACAQSGHEVTLSSLSLTMPPPKFHDTSSPLMATQSSAETHWAVRVEEKAKFDGIFES 137
            L+     G +    +L   + PPK    ++PL           A+   E+  +  +F +
Sbjct: 417 HLIRGLHKGLKAP-PTLPRKLTPPK----TAPLALP--------AITPPEREAYIKLFRA 557

Query: 138 L-LPVNGLLSGDKVKPVLMNSKLPLDVLGRVWDLSDIDKDGHLDRDEFAVAMHLV 191
           L +   G L GD  + V   S+L  DVL  VW+LSD+ +DG LD DEF VA HL+
Sbjct: 558 LDVQGKGFLDGDCCRHVFEASELTSDVLSDVWNLSDVTRDGKLDVDEFCVACHLL 722

 Score = 76.6 bits (187), Expect = 5e-14,   Method: Compositional matrix adjust.
 Identities = 57/223 (25%), Positives = 100/223 (44%), Gaps = 2/223 (0%)
 Frame = +3

Query: 119 THW-AVRVEEKAKFDGIFESLLPVNGLLSGDKVKPVLMNSKLPLDVLGRVWDLSDIDKDG 177
           T W  V  EE+  ++ +F S  PV+G + G+ V+ + + S L L VL ++W+L+D+  D 
Sbjct: 204 TEWPVVSDEERQLYELLFYSQGPVDGYILGEGVRDLFLKSGLSLRVLSQIWNLADVSNDN 383

Query: 178 HLDRDEFAVAMHLVYRALEKEPVXXXXXXXXXXXXKRKKTVFAGAVPVLPAS-PPPKDSL 236
            L+  EF++ MHL+ R L K                        A P LP    PPK + 
Sbjct: 384 VLNVHEFSLVMHLI-RGLHKG---------------------LKAPPTLPRKLTPPKTAP 497

Query: 237 RSTPXXXXXXXXXXXXXXXPKHSVKQPPVAWVVPVADKMRFDEIFLKTDLDLDGYVSGQE 296
            + P                      PP        ++  + ++F   D+   G++ G  
Sbjct: 498 LALPAIT-------------------PP--------EREAYIKLFRALDVQGKGFLDGDC 596

Query: 297 VKEIFMHSGLTQNLLAHIWALADTRQTGKLSKEQFALAMYFIQ 339
            + +F  S LT ++L+ +W L+D  + GKL  ++F +A + ++
Sbjct: 597 CRHVFEASELTSDVLSDVWNLSDVTRDGKLDVDEFCVACHLLR 725

 Score = 62.0 bits (149), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 34/109 (31%), Positives = 58/109 (53%), Gaps = 1/109 (0%)
 Frame = +3

Query: 260 VKQP-PVAWVVPVADKMRFDEIFLKTDLDLDGYVSGQEVKEIFMHSGLTQNLLAHIWALA 318
           VKQP    W V   ++ +  E+   +   +DGY+ G+ V+++F+ SGL+  +L+ IW LA
Sbjct: 186 VKQPDGTEWPVVSDEERQLYELLFYSQGPVDGYILGEGVRDLFLKSGLSLRVLSQIWNLA 365

Query: 319 DTRQTGKLSKEQFALAMYFIQQKVSKGIDPPQVLSPDMVPPSERGTPIP 367
           D      L+  +F+L M+ I + + KG+  P  L   + PP      +P
Sbjct: 366 DVSNDNVLNVHEFSLVMHLI-RGLHKGLKAPPTLPRKLTPPKTAPLALP 509
>19303
          Length = 676

 Score = 73.2 bits (178), Expect = 4e-13,   Method: Composition-based stats.
 Identities = 37/79 (46%), Positives = 50/79 (63%)
 Frame = -1

Query: 118 ETHWAVRVEEKAKFDGIFESLLPVNGLLSGDKVKPVLMNSKLPLDVLGRVWDLSDIDKDG 177
           +  W V   EK ++D  F  L P+NG +SG   K  ++ SKLP  VL +VW L+D+DKDG
Sbjct: 424 QEEWVVS-REKYEYDDSFSKLNPINGKVSGAAAKSEMVKSKLPNSVLSKVWKLADVDKDG 248

Query: 178 HLDRDEFAVAMHLVYRALE 196
            LD DE+A+A HL+   LE
Sbjct: 247 MLDADEWALANHLIKIKLE 191

 Score = 54.3 bits (129), Expect = 2e-07,   Method: Composition-based stats.
 Identities = 35/97 (36%), Positives = 56/97 (57%)
 Frame = -1

Query: 267 WVVPVADKMRFDEIFLKTDLDLDGYVSGQEVKEIFMHSGLTQNLLAHIWALADTRQTGKL 326
           WVV   +K  +D+ F K +  ++G VSG   K   + S L  ++L+ +W LAD  + G L
Sbjct: 415 WVVS-REKYEYDDSFSKLN-PINGKVSGAAAKSEMVKSKLPNSVLSKVWKLADVDKDGML 242

Query: 327 SKEQFALAMYFIQQKVSKGIDPPQVLSPDMVPPSERG 363
             +++ALA + I+ K+ +G D P  L   +VPPS+R 
Sbjct: 241 DADEWALANHLIKIKL-EGHDLPSDLPSHLVPPSKRA 134

 Score = 42.7 bits (99), Expect = 7e-04,   Method: Composition-based stats.
 Identities = 26/87 (29%), Positives = 44/87 (50%)
 Frame = -1

Query: 19  YESYYKQVDPAYTGRVGASEAALFLKKSGLSDIILGKIWDLADPEGKGFLDKQGFYVALR 78
           Y+  + +++P   G+V  + A   + KS L + +L K+W LAD +  G LD   + +A  
Sbjct: 388 YDDSFSKLNPI-NGKVSGAAAKSEMVKSKLPNSVLSKVWKLADVDKDGMLDADEWALANH 212

Query: 79  LVACAQSGHEVTLSSLSLTMPPPKFHD 105
           L+     GH++     S  +PP K  D
Sbjct: 211 LIKIKLEGHDLPSDLPSHLVPPSKRAD 131
>37000
          Length = 492

 Score = 72.8 bits (177), Expect = 6e-13,   Method: Compositional matrix adjust.
 Identities = 47/121 (38%), Positives = 77/121 (63%)
 Frame = -3

Query: 432 SLQELEAQKQDAQDRLDEMDQQKAKLRDMLSDVRQKCQDETQTISSLKTQIQSQESDLKS 491
           +L +LE+QK++AQ RLDE+D +K+ L   L ++R K   E   ++ LK+QI +Q+  +K+
Sbjct: 490 TLTQLESQKKEAQKRLDELDDKKSNLDRNLKEMRDKTSKEQMEVNKLKSQISNQDRLVKN 311

Query: 492 QEDDLNRAKSELNRLQQEETQLEQSIQAGRAQLETILRSLKCTQDDINQARSKLSQLQES 551
           QE +L+  + EL +L+ EE  LEQ++++ R QL  +  S K     I Q +SK+  LQ+ 
Sbjct: 310 QEGELDSLRQELQKLRDEEQSLEQNVESSRHQLSQLAASHKDISSQIMQTQSKVQALQDQ 131

Query: 552 H 552
           H
Sbjct: 130 H 128
>19700
          Length = 608

 Score = 37.7 bits (86), Expect = 0.022,   Method: Composition-based stats.
 Identities = 28/138 (20%), Positives = 61/138 (44%), Gaps = 7/138 (5%)
 Frame = -1

Query: 385 DDISQEIAQLQREKYSLEQDIREKEEAIRQKTSEVQELQNDLDRETSSLQELEAQKQDAQ 444
           DD+  E   L+REK    ++++  E  +      +Q L+ DL+R    LQ    + ++A 
Sbjct: 467 DDLKDENESLKREKNKWSEEVQRLESDLAGLNRRIQLLEEDLERSEERLQTATEKLEEAS 288

Query: 445 DRLDEMDQQKAKL-------RDMLSDVRQKCQDETQTISSLKTQIQSQESDLKSQEDDLN 497
              DE ++ +           + L DV  + +   Q     +++ +     L+  + DL 
Sbjct: 287 KAADESERGRRTAEKKMFTGEERLEDVETELRTAKQAAREWESRYEEVARRLQVMDHDLG 108

Query: 498 RAKSELNRLQQEETQLEQ 515
           +A+   +  +++  +LE+
Sbjct: 107 KAEYRADNSERKARELEE 54
>30643
          Length = 554

 Score = 30.4 bits (67), Expect = 3.2,   Method: Composition-based stats.
 Identities = 23/106 (21%), Positives = 44/106 (41%)
 Frame = -2

Query: 403 QDIREKEEAIRQKTSEVQELQNDLDRETSSLQELEAQKQDAQDRLDEMDQQKAKLRDMLS 462
           Q + E ++        +Q +QND+        ELE Q +   + L +  + + +L   + 
Sbjct: 319 QGLNEAKKQNHNLMERLQTMQNDVSESEVRCAELEGQIRQLNNLLVQRQEAEQELNQRMQ 140

Query: 463 DVRQKCQDETQTISSLKTQIQSQESDLKSQEDDLNRAKSELNRLQQ 508
             + + Q   + +SSL   + S E++ +  E    R K      QQ
Sbjct: 139 KSQSEKQALVERVSSLSRTLNSIENEKREVERSTVRPKKGERSRQQ 2
>14714
          Length = 546

 Score = 29.6 bits (65), Expect = 5.8,   Method: Composition-based stats.
 Identities = 14/40 (35%), Positives = 23/40 (57%)
 Frame = -1

Query: 71  QGFYVALRLVACAQSGHEVTLSSLSLTMPPPKFHDTSSPL 110
            G +V    +A   +GH+VTL+S++     P  H+T+ PL
Sbjct: 237 HGLFVCRGGLAAGPAGHDVTLASMAAV---PASHETTQPL 127
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|29244192|ref|NP_808393.1| leucine rich repeat
containing 8 family, member A [Mus musculus]
         (810 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

34576                                                                  79   5e-15
20480                                                                  62   4e-13
19531                                                                  62   7e-10
09309                                                                  61   2e-09
05532                                                                  52   8e-07
30747                                                                  51   2e-06
14078                                                                  35   0.093
08106                                                                  31   2.0  
16524                                                                  30   3.0  
17623                                                                  29   5.8  
>34576
          Length = 1496

 Score = 79.3 bits (194), Expect = 5e-15,   Method: Compositional matrix adjust.
 Identities = 70/239 (29%), Positives = 111/239 (46%), Gaps = 27/239 (11%)
 Frame = +2

Query: 588 KKMVNLTELELIRC---DLERIPHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRLTCL 644
           + +  L EL+ + C    L  IP SI    NL+ + L  N+L+ +   + F +L ++T L
Sbjct: 29  EDIAELFELKEVYCGSNQLTLIPESICWCSNLEILSLHKNHLERLP--VEFANLRKITRL 202

Query: 645 KLWYNHIAYIPIQIGNLTNLERLYLNRNKIEKIPTQLFYCRKLRYL-------------- 690
            L  N+   +P+ IG+LT LE L L+ N + +IP +L   +KL +L              
Sbjct: 203 ILSDNNFTSVPVAIGSLTELEALLLDGNSLHEIPQELGTLKKLTHLSLGRNAFKEFPRPA 382

Query: 691 ---------DLSHNNLTFLPADIGLLQNLQNLAVTANRIEALPPELFQCRKLRALHLGNN 741
                    DLS N +T +P+DI  L +L+ L +  N +     EL   +KL+     NN
Sbjct: 383 CSITSLEILDLSDNKITEIPSDIAQLLSLRELYMKKNAVSVFCAELCALQKLQMADFSNN 562

Query: 742 VLQSLPSRVGELTNLTQIELRGNRLECLPVELGECPLLKRSGLVVEEDL-FSTLPPEVK 799
            L  LP  V  L  L +++L  N+    P      P L +     +E L   +LP E++
Sbjct: 563 GLLDLPEEVSVLGCLQELDLSNNQFFEFPKTACSIPHLHKLVFSQQEGLKVPSLPDEIE 739

 Score = 36.2 bits (82), Expect = 0.049,   Method: Compositional matrix adjust.
 Identities = 23/78 (29%), Positives = 44/78 (56%)
 Frame = +2

Query: 718 NRIEALPPELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLECLPVELGECP 777
           N +  LP ++ +  +L+ ++ G+N L  +P  +   +NL  + L  N LE LPVE     
Sbjct: 8   NCLTVLPEDIAELFELKEVYCGSNQLTLIPESICWCSNLEILSLHKNHLERLPVEFAN-- 181

Query: 778 LLKRSGLVVEEDLFSTLP 795
           L K + L++ ++ F+++P
Sbjct: 182 LRKITRLILSDNNFTSVP 235
>20480
          Length = 638

 Score = 62.0 bits (149), Expect(2) = 4e-13,   Method: Composition-based stats.
 Identities = 40/129 (31%), Positives = 71/129 (55%)
 Frame = -1

Query: 671 RNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQNLQNLAVTANRIEALPPELFQC 730
           R +++ +   +F   KL+ LDLS+N++  + +++  LQ L+ L +  N++EA+P  +   
Sbjct: 476 RQQLQAVNRSVFRLPKLQILDLSNNDIEAVSSELSGLQTLRQLILNGNKMEAIPGSIGFM 297

Query: 731 RKLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLECLPVELGECPLLKRSGLVVEEDL 790
           ++LR L +  N L+ +P  +G L NL  + L  N LE L   + +   L R GL    + 
Sbjct: 296 KELRVLGVNENRLREVPDSIGNLENLEILGLERNCLEFLNPVVCKLEGLLRLGL--SGNH 123

Query: 791 FSTLPPEVK 799
            + LP EV+
Sbjct: 122 MTNLPREVE 96

 Score = 31.2 bits (69), Expect(2) = 4e-13,   Method: Compositional matrix adjust.
 Identities = 17/36 (47%), Positives = 20/36 (55%)
 Frame = -2

Query: 638 LHRLTCLKLWYNHIAYIPIQIGNLTNLERLYLNRNK 673
           L +L CL L  N I  IP  I +L NLE L L+ N 
Sbjct: 574 LEQLVCLSLSNNKITEIPDAISHLDNLEVLVLSGNS 467

 Score = 50.1 bits (118), Expect = 4e-06,   Method: Composition-based stats.
 Identities = 37/119 (31%), Positives = 60/119 (50%)
 Frame = -1

Query: 586 SLKKMVNLTELELIRCDLERIPHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRLTCLK 645
           S+ ++  L  L+L   D+E +   +  L  L+++ L  N ++ I   I F  +  L  L 
Sbjct: 449 SVFRLPKLQILDLSNNDIEAVSSELSGLQTLRQLILNGNKMEAIPGSIGF--MKELRVLG 276

Query: 646 LWYNHIAYIPIQIGNLTNLERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADI 704
           +  N +  +P  IGNL NLE L L RN +E +   +     L  L LS N++T LP ++
Sbjct: 275 VNENRLREVPDSIGNLENLEILGLERNCLEFLNPVVCKLEGLLRLGLSGNHMTNLPREV 99
>19531
          Length = 415

 Score = 62.4 bits (150), Expect = 7e-10,   Method: Compositional matrix adjust.
 Identities = 39/116 (33%), Positives = 61/116 (52%)
 Frame = -2

Query: 641 LTCLKLWYNHIAYIPIQIGNLTNLERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFL 700
           LT L L  N +  +   +  L  L  L ++ N ++ +P  L     L+ L++SHN L  L
Sbjct: 366 LTKLILASNALTSLGEGLAQLPALTVLDVHDNHLQSLPNALGELENLQKLNISHNQLVEL 187

Query: 701 PADIGLLQNLQNLAVTANRIEALPPELFQCRKLRALHLGNNVLQSLPSRVGELTNL 756
           P+ IG L NL ++    N++  + P+L  CRKL  L + NN L  LP  +G L+ +
Sbjct: 186 PSCIGRLSNLVSVHAEHNKLTLICPDLVDCRKLEELDVSNNDLAELPKYIGLLSRM 19

 Score = 58.2 bits (139), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 42/128 (32%), Positives = 66/128 (51%)
 Frame = -2

Query: 589 KMVNLTELELIRCDLERIPHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWY 648
           +  +LT+L L    L  +   +  L  L  +D+ DN+L+++    +   L  L  L + +
Sbjct: 378 EQTDLTKLILASNALTSLGEGLAQLPALTVLDVHDNHLQSLPN--ALGELENLQKLNISH 205

Query: 649 NHIAYIPIQIGNLTNLERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQ 708
           N +  +P  IG L+NL  ++   NK+  I   L  CRKL  LD+S+N+L  LP  IGLL 
Sbjct: 204 NQLVELPSCIGRLSNLVSVHAEHNKLTLICPDLVDCRKLEELDVSNNDLAELPKYIGLLS 25

Query: 709 NLQNLAVT 716
            +  L V 
Sbjct: 24  RMFRLNVA 1

 Score = 38.9 bits (89), Expect = 0.009,   Method: Compositional matrix adjust.
 Identities = 24/66 (36%), Positives = 38/66 (57%)
 Frame = -2

Query: 709 NLQNLAVTANRIEALPPELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLEC 768
           +L  L + +N + +L   L Q   L  L + +N LQSLP+ +GEL NL ++ +  N+L  
Sbjct: 369 DLTKLILASNALTSLGEGLAQLPALTVLDVHDNHLQSLPNALGELENLQKLNISHNQLVE 190

Query: 769 LPVELG 774
           LP  +G
Sbjct: 189 LPSCIG 172
>09309
          Length = 1508

 Score = 61.2 bits (147), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 42/142 (29%), Positives = 75/142 (52%), Gaps = 2/142 (1%)
 Frame = +3

Query: 641 LTCLKLWYNHIAYIPIQIGNLTN-LERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTF 699
           +T + +  N    +P  +  L N L  L +  NK+  +   +    KL  LDL +N L+ 
Sbjct: 438 VTSVNISKNQFTQLPSNLFLLVNSLTELNMGFNKLTGLSPDIGLFLKLTCLDLRNNGLSS 617

Query: 700 LPADIGLLQNLQNLAVTANRIEALPPELFQCRKLRALHLGNNVLQSL-PSRVGELTNLTQ 758
           LPA++  +Q L+ + ++ NR   +P  L++ +KL  L L +N + ++ PS +  L  L  
Sbjct: 618 LPAELCSMQALREVILSCNRFTEIPQALYELKKLEILFLNDNQVSTIEPSGLQRLGVLAT 797

Query: 759 IELRGNRLECLPVELGECPLLK 780
           ++L+ N +  +P ELG C  L+
Sbjct: 798 LDLQNNNISQVPPELGNCTSLR 863

 Score = 48.9 bits (115), Expect = 9e-06,   Method: Compositional matrix adjust.
 Identities = 47/151 (31%), Positives = 64/151 (42%), Gaps = 2/151 (1%)
 Frame = +3

Query: 593 LTELELIRCDLERIPHSIFSLHNLQEIDLKDNNLKTI-EEIISFQHLHRLTCLKLWYNHI 651
           LTEL +    L  +   I     L  +DL++N L ++  E+ S Q L  +    L  N  
Sbjct: 510 LTELNMGFNKLTGLSPDIGLFLKLTCLDLRNNGLSSLPAELCSMQALREVI---LSCNRF 680

Query: 652 AYIPIQIGNLTNLERLYLNRNKIEKI-PTQLFYCRKLRYLDLSHNNLTFLPADIGLLQNL 710
             IP  +  L  LE L+LN N++  I P+ L     L  LDL +NN              
Sbjct: 681 TEIPQALYELKKLEILFLNDNQVSTIEPSGLQRLGVLATLDLQNNN-------------- 818

Query: 711 QNLAVTANRIEALPPELFQCRKLRALHLGNN 741
                    I  +PPEL  C  LR+L LG N
Sbjct: 819 ---------ISQVPPELGNCTSLRSLQLGGN 884

 Score = 38.9 bits (89), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 25/70 (35%), Positives = 35/70 (50%)
 Frame = +3

Query: 635 FQHLHRLTCLKLWYNHIAYIPIQIGNLTNLERLYLNRNKIEKIPTQLFYCRKLRYLDLSH 694
            QHL  L  L +  N +A +P +I  L NLERL L+ N I  +P  L     L+ + L  
Sbjct: 6   LQHLSTLNFLDVRDNKLAKLPDEITLLENLERLDLSNNDISMLPYSLGTINSLKSVILDG 185

Query: 695 NNLTFLPADI 704
           N +  +  DI
Sbjct: 186 NPMKSIRRDI 215

 Score = 37.7 bits (86), Expect = 0.017,   Method: Compositional matrix adjust.
 Identities = 18/63 (28%), Positives = 39/63 (61%)
 Frame = +3

Query: 661 LTNLERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQNLQNLAVTANRI 720
           L+ L  L +  NK+ K+P ++     L  LDLS+N+++ LP  +G + +L+++ +  N +
Sbjct: 15  LSTLNFLDVRDNKLAKLPDEITLLENLERLDLSNNDISMLPYSLGTINSLKSVILDGNPM 194

Query: 721 EAL 723
           +++
Sbjct: 195 KSI 203
>05532
          Length = 1607

 Score = 52.4 bits (124), Expect = 8e-07,   Method: Compositional matrix adjust.
 Identities = 28/68 (41%), Positives = 40/68 (58%)
 Frame = +3

Query: 707 LQNLQNLAVTANRIEALPPELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRL 766
            Q+L  L +  NR++ + P + Q   L  L L +N L SLPS +G+LT L ++ L  N+L
Sbjct: 174 FQHLTCLYLNDNRLDHISPHVSQLHHLVCLDLSSNQLSSLPSEIGDLTELRELLLYNNQL 353

Query: 767 ECLPVELG 774
             LP ELG
Sbjct: 354 TSLPFELG 377

 Score = 50.8 bits (120), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 31/93 (33%), Positives = 51/93 (54%)
 Frame = +3

Query: 674 IEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQNLQNLAVTANRIEALPPELFQCRKL 733
           +  I  +LF  + L  L L+ N L  +   +  L +L  L +++N++ +LP E+    +L
Sbjct: 144 VRNISPELFRFQHLTCLYLNDNRLDHISPHVSQLHHLVCLDLSSNQLSSLPSEIGDLTEL 323

Query: 734 RALHLGNNVLQSLPSRVGELTNLTQIELRGNRL 766
           R L L NN L SLP  +G L  L  ++++GN L
Sbjct: 324 RELLLYNNQLTSLPFELGRLFQLQNLDIKGNPL 422

 Score = 47.0 bits (110), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 29/77 (37%), Positives = 45/77 (58%)
 Frame = +3

Query: 667 LYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQNLQNLAVTANRIEALPPE 726
           LYLN N+++ I   +     L  LDLS N L+ LP++IG L  L+ L +  N++ +LP E
Sbjct: 192 LYLNDNRLDHISPHVSQLHHLVCLDLSSNQLSSLPSEIGDLTELRELLLYNNQLTSLPFE 371

Query: 727 LFQCRKLRALHLGNNVL 743
           L +  +L+ L +  N L
Sbjct: 372 LGRLFQLQNLDIKGNPL 422
>30747
          Length = 1168

 Score = 50.8 bits (120), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 53/174 (30%), Positives = 92/174 (52%), Gaps = 2/174 (1%)
 Frame = +3

Query: 575 NNEGTKLIVLNSLKKMVNLTELELIRCDLERIPHSIFSLHNLQEIDLKDNNLKTIE--EI 632
           +N+ +++  L SLK+   L  L+L    +E +   + +L  L+ + L  N L  ++  E+
Sbjct: 354 DNKVSQVQGLESLKE---LCSLQLQYNQIESLGKGLNALKKLKCLRLDSNRLTKLDTNEL 524

Query: 633 ISFQHLHRLTCLKLWYNHIAYIPIQIGNLTNLERLYLNRNKIEKIPTQLFYCRKLRYLDL 692
           +S  ++   + L L  NHI  +   +  L NLE L+++ N I+K+ T L  C+KL  LDL
Sbjct: 525 LSCVNI---STLDLSNNHITNLS-ALSYLPNLEELFVSGNSIQKL-TDLHRCKKLSELDL 689

Query: 693 SHNNLTFLPADIGLLQNLQNLAVTANRIEALPPELFQCRKLRALHLGNNVLQSL 746
           S N L  +    G L  LQ L ++ NR++++   L + + L  L+L  N +  L
Sbjct: 690 SRNRLVDISGISG-LPALQTLDMSDNRLKSV-TSLGKLKSLETLNLNGNQISEL 845
>14078
          Length = 1045

 Score = 35.4 bits (80), Expect = 0.093,   Method: Compositional matrix adjust.
 Identities = 23/59 (38%), Positives = 31/59 (52%)
 Frame = -1

Query: 706 LLQNLQNLAVTANRIEALPPELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGN 764
           LL   Q L + AN I+ +   L +C  L  LHL +N L+SL     +L  L  + LRGN
Sbjct: 373 LLTQHQKLVLAANVIKRIEG-LGRCAGLTTLHLRDNQLESLDGFTDDLKELQYVNLRGN 200

 Score = 29.3 bits (64), Expect = 7.2,   Method: Compositional matrix adjust.
 Identities = 33/103 (32%), Positives = 46/103 (44%), Gaps = 21/103 (20%)
 Frame = -2

Query: 687 LRYLDLSHNNLT------------FLPADIGLLQN--------LQNLAVTANRIEALPPE 726
           +RY+D+S N L              L AD  LL +        LQ  + T N+I +   E
Sbjct: 687 VRYVDISKNALKDISPLSALTHMLTLKADENLLTSVQLEEMPFLQVASFTHNKISS--TE 514

Query: 727 LFQCRKLRALHLGNNVLQSLPSRVG-ELTNLTQIELRGNRLEC 768
            F    L  L L NN +  +    G +L+ L  +ELRGN+LE 
Sbjct: 513 GFNHPMLEHLILNNNNISQVTGLDGTKLSRLHTLELRGNKLET 385
>08106
          Length = 997

 Score = 31.2 bits (69), Expect = 2.0,   Method: Compositional matrix adjust.
 Identities = 23/64 (35%), Positives = 33/64 (51%), Gaps = 2/64 (3%)
 Frame = +2

Query: 719 RIEALPPELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLECL--PVELGEC 776
           RIE L     +C  L  LHL +N L++L     EL  L  + +RGN L  +    +L + 
Sbjct: 20  RIEGLG----RCVSLATLHLRDNQLENLDGFTEELKELQYVNVRGNLLTSIKEAAKLKDL 187

Query: 777 PLLK 780
           PLL+
Sbjct: 188 PLLR 199
>16524
          Length = 354

 Score = 30.4 bits (67), Expect = 3.0,   Method: Composition-based stats.
 Identities = 17/46 (36%), Positives = 25/46 (54%), Gaps = 1/46 (2%)
 Frame = -2

Query: 306 RTYRCAHPLATLFKILASFYISLVIFYGLICMYTLWWMLR-RSLKK 350
           + Y C H +    K + SF+ S   FY +I +YT   M+  +SLKK
Sbjct: 149 KCYVCEHVVYACVKCV*SFFTSTACFYNIIYIYTATHMMPLKSLKK 12
>17623
          Length = 687

 Score = 29.3 bits (64), Expect = 5.8,   Method: Compositional matrix adjust.
 Identities = 18/69 (26%), Positives = 39/69 (56%)
 Frame = +2

Query: 578 GTKLIVLNSLKKMVNLTELELIRCDLERIPHSIFSLHNLQEIDLKDNNLKTIEEIISFQH 637
            T L  + +L  +VNL EL L    +E++ HS+ S  +L++++L  N + ++ ++ +   
Sbjct: 287 ATLLKNIENLTHLVNLKELNLAENKIEKLGHSLDSNIHLEDLNLSGNPISSLRDVTNLVR 466

Query: 638 LHRLTCLKL 646
           L +L  + +
Sbjct: 467 LPQLQSVSM 493
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|85986575|ref|NP_001028374.1| ubiquitin specific
peptidase 30 [Mus musculus]
         (517 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

30019                                                                  79   5e-15
11884                                                                  47   2e-05
03515                                                                  45   1e-04
35122                                                                  40   0.002
07949                                                                  32   0.64 
34092                                                                  31   1.4  
17940                                                                  29   3.6  
01549                                                                  29   5.3  
00779                                                                  28   6.3  
21279                                                                  28   7.7  
>30019
          Length = 394

 Score = 78.6 bits (192), Expect = 5e-15,   Method: Compositional matrix adjust.
 Identities = 43/120 (35%), Positives = 63/120 (52%)
 Frame = +1

Query: 232 MVCKHCEHQSPVRFDTFDSLSLSIPAATWGHPLTLDHCLHHFISSESVRDVVCDNCTKIE 291
           +VC  C  +S VR+D FDS++L++P       L+L H L  +I+SE + DV CD+C    
Sbjct: 76  IVCNGCGSKSAVRYDKFDSVTLNLPEQRRS-GLSLGHLLSEYITSEDLSDVKCDSC---- 240

Query: 292 ARGTLTGEKVEHQRSTFVKQLKLGKLPQCLCIHLQRLSWSSHGTPLKRHEHVQFNEFLMM 351
                      ++ +   K +   KLP CLCIH+ R  W + G   KR ++V F E L M
Sbjct: 241 -----------NEATMHTKSVTFAKLPACLCIHIARTIWLNTGQLCKRQDYVHFPESLSM 387
>11884
          Length = 952

 Score = 47.0 bits (110), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 25/74 (33%), Positives = 37/74 (50%), Gaps = 1/74 (1%)
 Frame = +3

Query: 436 FRLMAVVVHHGD-MHSGHFVTYRRSPPSAKNPLSTSNQWLWISDDTVRKASLQEVLSSSA 494
           + L  V++H G   + GH+  Y RSP         +N W  ++D +V + S   V  S A
Sbjct: 387 YHLYGVLIHSGHHCNMGHYYCYVRSP---------ANSWYIMNDSSVHQVSASRVFGSQA 539

Query: 495 YLLFYERVLSRVQQ 508
           YLLFY + +   QQ
Sbjct: 540 YLLFYTKAVPSFQQ 581
>03515
          Length = 2030

 Score = 44.7 bits (104), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 20/66 (30%), Positives = 36/66 (54%)
 Frame = -1

Query: 436  FRLMAVVVHHGDMHSGHFVTYRRSPPSAKNPLSTSNQWLWISDDTVRKASLQEVLSSSAY 495
            + L A+  H G M  GH+V Y ++P         + +W   +D + ++    ++ ++SAY
Sbjct: 1967 YDLYAMSCHTGIMGGGHYVAYSKNP---------NGKWYCYNDSSCKEVQEDQLDTNSAY 1815

Query: 496  LLFYER 501
            +LFYER
Sbjct: 1814 ILFYER 1797
>35122
          Length = 1031

 Score = 40.0 bits (92), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 18/43 (41%), Positives = 24/43 (55%)
 Frame = -3

Query: 69  GLVNLGNTCFMNSLLQGLSACPAFVKWLEEFTTQYSRDQQGPH 111
           GL NLGNTC+MN+ +Q L A P     L+ +T   +     PH
Sbjct: 765 GLANLGNTCYMNATIQCLRAVPELRDALKSYTGNMTLGVPPPH 637
>07949
          Length = 703

 Score = 32.0 bits (71), Expect = 0.64,   Method: Compositional matrix adjust.
 Identities = 16/35 (45%), Positives = 21/35 (60%)
 Frame = +2

Query: 224 FHGRLTSNMVCKHCEHQSPVRFDTFDSLSLSIPAA 258
           F G+  S +VC  C+H S V ++ F  LSL IP A
Sbjct: 353 FQGQFKSTVVCSECDHVS-VTYEPFMYLSLPIPYA 454
>34092
          Length = 1009

 Score = 30.8 bits (68), Expect = 1.4,   Method: Compositional matrix adjust.
 Identities = 20/36 (55%), Positives = 22/36 (61%), Gaps = 4/36 (11%)
 Frame = -1

Query: 65  GLV---PGLVNLG-NTCFMNSLLQGLSACPAFVKWL 96
           GLV   PGL N G N CFMN++LQ LS  P  V  L
Sbjct: 979 GLVKKPPGLRNKGQNHCFMNAVLQCLSRSPYLVPCL 872
>17940
          Length = 502

 Score = 29.3 bits (64), Expect = 3.6,   Method: Composition-based stats.
 Identities = 13/28 (46%), Positives = 17/28 (60%)
 Frame = -3

Query: 231 NMVCKHCEHQSPVRFDTFDSLSLSIPAA 258
           NMV K C H S V++  F SL L +P +
Sbjct: 131 NMVLKSCAHSSAVQYWFFSSLDLIVPMS 48
>01549
          Length = 2495

 Score = 28.9 bits (63), Expect = 5.3,   Method: Compositional matrix adjust.
 Identities = 17/53 (32%), Positives = 25/53 (47%)
 Frame = +2

Query: 226 GRLTSNMVCKHCEHQSPVRFDTFDSLSLSIPAATWGHPLTLDHCLHHFISSES 278
           GRL S+   +    + P+R D   + S  +P      PL L  CLH F+ + S
Sbjct: 812 GRLLSDWAQRSRWQEDPLRADMGWACSHQVPPRRLLFPLKLTLCLHRFLHTSS 970
>00779
          Length = 1185

 Score = 28.5 bits (62), Expect = 6.3,   Method: Compositional matrix adjust.
 Identities = 15/45 (33%), Positives = 22/45 (48%)
 Frame = -1

Query: 315 GKLPQCLCIHLQRLSWSSHGTPLKRHEHVQFNEFLMMDFYKYRLL 359
           G+  + +C+HL RLSW  HG   +   H +     M   Y+  LL
Sbjct: 732 GQQDEGVCLHLLRLSWRLHGHEGQVAHHGRHQGQYMSGLYRDSLL 598
>21279
          Length = 908

 Score = 28.5 bits (62), Expect = 7.7,   Method: Compositional matrix adjust.
 Identities = 15/34 (44%), Positives = 22/34 (64%), Gaps = 1/34 (2%)
 Frame = +2

Query: 469 TSNQWLWISDDTVRKASLQEVL-SSSAYLLFYER 501
            S++W   +D++V     +  L SSSAY+LFYER
Sbjct: 23  VSHKWHEFNDNSVSDTIPENCLVSSSAYILFYER 124
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|165972321|ref|NP_666187.2| LEM domain containing 2
[Mus musculus]
         (511 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

18209                                                                  78   8e-15
24881                                                                  77   2e-14
21012                                                                  30   3.0  
30227                                                                  29   4.4  
01601                                                                  28   6.2  
>18209
          Length = 435

 Score = 78.2 bits (191), Expect = 8e-15,   Method: Composition-based stats.
 Identities = 33/91 (36%), Positives = 62/91 (68%), Gaps = 1/91 (1%)
 Frame = +1

Query: 413 EEEEQAMYEMVKKIIDVVQD-HYVDWEQDMERYPYVGILHVRDSLIPPQSRRRMKRVWDR 471
           E E+Q ++ MV++IID++++ H     +D      + + HVRD L+PP  R+ M+++W++
Sbjct: 1   EREQQKVFAMVEQIIDLLKEQHEFVQNEDTTEQAGLPVQHVRDQLLPPARRKAMQKIWEQ 180

Query: 472 AVEFLASNESRIQTESHRVAGEDMLVWRWTK 502
           AV+F+ +NESR++ E+  + G++  VWRW +
Sbjct: 181 AVKFIEANESRVRLETQIIEGDEFEVWRWIQ 273
>24881
          Length = 627

 Score = 76.6 bits (187), Expect = 2e-14,   Method: Compositional matrix adjust.
 Identities = 33/91 (36%), Positives = 62/91 (68%), Gaps = 1/91 (1%)
 Frame = +1

Query: 413 EEEEQAMYEMVKKIIDVVQD-HYVDWEQDMERYPYVGILHVRDSLIPPQSRRRMKRVWDR 471
           E E+Q ++ MV++IID++++ H     +D      + + HVRD L+PP  R+ M+++W++
Sbjct: 1   EREQQKVFAMVEQIIDLLKEQHEFVQNEDTTEQAGLPVQHVRDQLLPPARRKAMQKIWEQ 180

Query: 472 AVEFLASNESRIQTESHRVAGEDMLVWRWTK 502
           AV+F+ +NESR++ E+  + G++  VWRW +
Sbjct: 181 AVKFIEANESRVRLETQIIEGDEFEVWRWIQ 273
>21012
          Length = 412

 Score = 29.6 bits (65), Expect = 3.0,   Method: Composition-based stats.
 Identities = 11/20 (55%), Positives = 16/20 (80%)
 Frame = +3

Query: 407 YRWRKLEEEEQAMYEMVKKI 426
           +RWRKLE  + + YEM++KI
Sbjct: 153 HRWRKLEGSDPSTYEMIQKI 212
>30227
          Length = 397

 Score = 29.3 bits (64), Expect = 4.4,   Method: Composition-based stats.
 Identities = 18/53 (33%), Positives = 20/53 (37%)
 Frame = +3

Query: 287 FLAIQAGNFECGNPEKLKSKCIPVLEAQEYIANVTSSPSSRFKAALTWILSSN 339
           F   Q   +E G       KC    E QE I      PSS F    TW L +N
Sbjct: 141 FAG*QHSEYEAG-------KCTYTCEDQETICTFLPRPSSAFSNITTWYLQNN 278
>01601
          Length = 810

 Score = 28.5 bits (62), Expect = 6.2,   Method: Compositional matrix adjust.
 Identities = 14/29 (48%), Positives = 17/29 (58%)
 Frame = -3

Query: 371 MGIGCRLSRALLTAVTHVLIFFWCLAFLW 399
           M   CRL+   L  VT +LI F C+A LW
Sbjct: 196 MNGCCRLAEPRLNKVTQLLIGFGCIAVLW 110
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|124286811|ref|NP_035034.2| neurofilament, heavy
polypeptide [Mus musculus]
         (1090 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

11243                                                                  79   1e-14
02016                                                                  65   2e-10
22014                                                                  54   3e-07
26996                                                                  44   4e-04
26781                                                                  37   0.033
05987                                                                  30   4.3  
11942                                                                  30   5.4  
34682                                                                  29   9.0  
>11243
          Length = 828

 Score = 79.0 bits (193), Expect = 1e-14,   Method: Compositional matrix adjust.
 Identities = 65/227 (28%), Positives = 118/227 (51%), Gaps = 8/227 (3%)
 Frame = -2

Query: 213 ELQKKAQALQEECGYLRRHHQEEVGELLXXXXXXXXXXXXXXXEARDALKCDVTSA---- 268
           +L+ + ++L+EE  YL+++H+EE+                    AR  +   V SA    
Sbjct: 767 DLELEIESLKEELIYLKKNHEEELA--------------VVRSSARGNVDVQVDSAPPVD 630

Query: 269 ----LREIRAQLEGHAVQSTLQSEEWFRVRLDRLSEAAKVNTDAMRSAQEEITEYRRQLQ 324
               + ++R+Q E    ++  + E  ++ + + L+     NT A+++++  IT+ +R +Q
Sbjct: 629 LAQIMXDVRSQYESMMEKNRQELEACYKGQSENLNHEVATNTAALQTSKTAITDLKRTIQ 450

Query: 325 ARTTELEALKSTKESLERQRSELEDRHQADIASYQDAIQQLDSELRNTKWEMAAQLREYQ 384
           +   EL++L S K +LE   +E E ++ A +   Q  I Q++ EL+N + +   Q  EY+
Sbjct: 449 SLEIELQSLLSMKGALEGTLAETEAQYGAQLNHLQAMITQVEMELQNLRSDADHQSLEYK 270

Query: 385 DLLNVKMALDIEIAAYRKLLEGEECRIGFGPSPFSLTEGLPKIPSIS 431
            LL+ K  L++EIA YR+LLEGE+ R       FS TE    +  +S
Sbjct: 269 RLLDAKTRLEMEIATYRRLLEGEDTR-------FSQTETQKAVTIVS 150
>02016
          Length = 3061

 Score = 64.7 bits (156), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 58/154 (37%), Positives = 80/154 (51%), Gaps = 8/154 (5%)
 Frame = +3

Query: 268 ALREIRAQLEGHAVQSTLQSEEWFRVRLDRLSE--AAKVNTDAMRS------AQEEITEY 319
           ALREIRAQ E     S LQ+    RV L+ L E   A +   A RS      A EE+   
Sbjct: 354 ALREIRAQHE-----SDLQT---VRVELETLYENKIADLKAQANRSNSASGSAWEELRIT 509

Query: 320 RRQLQARTTELEALKSTKESLERQRSELEDRHQADIASYQDAIQQLDSELRNTKWEMAAQ 379
           R++      EL  LK+     E + S+LE +   +   ++  + Q D EL   +  +  Q
Sbjct: 510 RKRADDLGAELAKLKAETAGFELRISDLESQLAREREEFRLRLAQKDDELAELRLTLEEQ 689

Query: 380 LREYQDLLNVKMALDIEIAAYRKLLEGEECRIGF 413
           ++EY DLL++K+ LD EI AYRKLLE EE R+  
Sbjct: 690 MQEYSDLLDIKIRLDREIDAYRKLLESEESRLNI 791
>22014
          Length = 353

 Score = 54.3 bits (129), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 27/54 (50%), Positives = 36/54 (66%)
 Frame = -1

Query: 362 IQQLDSELRNTKWEMAAQLREYQDLLNVKMALDIEIAAYRKLLEGEECRIGFGP 415
           + QL  E+   + EM A L E Q L++ K++L++EIAAYRKLLE EE R G  P
Sbjct: 212 VNQLKEEMNKLRAEMEAMLVELQTLMDAKLSLELEIAAYRKLLETEESRTGLPP 51
>26996
          Length = 386

 Score = 43.9 bits (102), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 18/26 (69%), Positives = 20/26 (76%)
 Frame = -1

Query: 95  EKEQLQALNDRFAGYIDKVRQLEAHN 120
           E+E LQ LNDR A YID+VR LEA N
Sbjct: 224 EQESLQGLNDRLANYIDRVRFLEAEN 147
>26781
          Length = 446

 Score = 31.2 bits (69), Expect(2) = 0.033,   Method: Compositional matrix adjust.
 Identities = 19/74 (25%), Positives = 29/74 (39%)
 Frame = +1

Query: 625 SPAEAKSPAEAKSPATVKSPGEAKSPSEAKSPAEAKSPAEAKSPAEAKSPAEVKSPGEAK 684
            P     P    +P + + PG    P    +P    SP     P    SP     PG+  
Sbjct: 196 GPVSPGEPGNPDNPFSPRGPGRPLGPDTPLNPGSPPSPFMPGKPGRPPSPLGPGIPGKPG 375

Query: 685 SPAEPKSPAEAKSP 698
            P+ P +P++ +SP
Sbjct: 376 RPSLPGTPSKPRSP 417

 Score = 25.0 bits (53), Expect(2) = 0.033,   Method: Compositional matrix adjust.
 Identities = 20/56 (35%), Positives = 22/56 (39%)
 Frame = +3

Query: 535 SPAEAKSPGEAKSPGEAKSPGEAKSPAEPKSPAEPKSPAEAKSPAEPKSPATVKSP 590
           SP    SPG    PG   SP     P  P  P  P  P  A SP  P +P +   P
Sbjct: 3   SPFSPGSPGRPSGPGAPGSPSLPGRPGTPGFPWRPGRPCRA-SPGNPDTPGSPSMP 167

 Score = 37.0 bits (84), Expect = 0.048,   Method: Compositional matrix adjust.
 Identities = 23/74 (31%), Positives = 31/74 (41%)
 Frame = +1

Query: 535 SPAEAKSPGEAKSPGEAKSPGEAKSPAEPKSPAEPKSPAEAKSPAEPKSPATVKSPGEAK 594
            P     PG   +P   + PG    P  P +P  P SP     P  P SP     PG+  
Sbjct: 196 GPVSPGEPGNPDNPFSPRGPGRPLGPDTPLNPGSPPSPFMPGKPGRPPSPLGPGIPGKPG 375

Query: 595 SPSEAKSPAEAKSP 608
            PS   +P++ +SP
Sbjct: 376 RPSLPGTPSKPRSP 417

 Score = 36.6 bits (83), Expect = 0.052,   Method: Compositional matrix adjust.
 Identities = 25/74 (33%), Positives = 33/74 (44%)
 Frame = +1

Query: 523 SPGEAKSPGEAKSPAEAKSPGEAKSPGEAKSPGEAKSPAEPKSPAEPKSPAEAKSPAEPK 582
           SPGE   PG   +P   + PG    P    +PG   SP  P  P  P SP     P +P 
Sbjct: 205 SPGE---PGNPDNPFSPRGPGRPLGPDTPLNPGSPPSPFMPGKPGRPPSPLGPGIPGKPG 375

Query: 583 SPATVKSPGEAKSP 596
            P+   +P + +SP
Sbjct: 376 RPSLPGTPSKPRSP 417

 Score = 30.0 bits (66), Expect(2) = 0.065,   Method: Compositional matrix adjust.
 Identities = 22/74 (29%), Positives = 30/74 (40%)
 Frame = +1

Query: 589 SPGEAKSPSEAKSPAEAKSPAEAKSPAEAKSPAEAKSPAEAKSPAEAKSPATVKSPGEAK 648
           SPGE  +P    SP   + P     P    +P    SP     P    SP     PG+  
Sbjct: 205 SPGEPGNPDNPFSP---RGPGRPLGPDTPLNPGSPPSPFMPGKPGRPPSPLGPGIPGKPG 375

Query: 649 SPSEAKSPAEAKSP 662
            PS   +P++ +SP
Sbjct: 376 RPSLPGTPSKPRSP 417

 Score = 25.4 bits (54), Expect(2) = 0.065,   Method: Compositional matrix adjust.
 Identities = 18/54 (33%), Positives = 23/54 (42%), Gaps = 2/54 (3%)
 Frame = +3

Query: 529 SPGEAKSPAEAKSPGEAKSPGEAKSPGEAKSPAEP--KSPAEPKSPAEAKSPAE 580
           SPG    P+   +PG    PG   +PG    P  P   SP  P +P     PA+
Sbjct: 12  SPGSPGRPSGPGAPGSPSLPGRPGTPGFPWRPGRPCRASPGNPDTPGSPSMPAD 173

 Score = 36.2 bits (82), Expect = 0.081,   Method: Compositional matrix adjust.
 Identities = 24/74 (32%), Positives = 33/74 (44%)
 Frame = +1

Query: 547 SPGEAKSPGEAKSPAEPKSPAEPKSPAEAKSPAEPKSPATVKSPGEAKSPSEAKSPAEAK 606
           SPGE   PG   +P  P+ P  P  P    +P  P SP     PG   SP     P +  
Sbjct: 205 SPGE---PGNPDNPFSPRGPGRPLGPDTPLNPGSPPSPFMPGKPGRPPSPLGPGIPGKPG 375

Query: 607 SPAEAKSPAEAKSP 620
            P+   +P++ +SP
Sbjct: 376 RPSLPGTPSKPRSP 417

 Score = 30.8 bits (68), Expect(2) = 0.16,   Method: Compositional matrix adjust.
 Identities = 24/81 (29%), Positives = 33/81 (40%)
 Frame = +1

Query: 656 PAEAKSPAEAKSPAEAKSPAEVKSPGEAKSPAEPKSPAEAKSPAEVKSPAEAKSPAEVKS 715
           P    SP E  +P    SP   + PG    P  P +P    SP     P    SP     
Sbjct: 190 PLGPVSPGEPGNPDNPFSP---RGPGRPLGPDTPLNPGSPPSPFMPGKPGRPPSPLGPGI 360

Query: 716 PGEAKSPAAVKSPAEAKSPAA 736
           PG+   P+   +P++ +SP A
Sbjct: 361 PGKPGRPSLPGTPSKPRSPFA 423

 Score = 23.1 bits (48), Expect(2) = 0.16,   Method: Compositional matrix adjust.
 Identities = 19/58 (32%), Positives = 21/58 (36%)
 Frame = +3

Query: 577 SPAEPKSPATVKSPGEAKSPSEAKSPAEAKSPAEAKSPAEAKSPAEAKSPAEAKSPAE 634
           SP  P SP     PG   SPS    P     P     P  A SP    +P     PA+
Sbjct: 3   SPFSPGSPGRPSGPGAPGSPSLPGRPGTPGFPWRPGRPCRA-SPGNPDTPGSPSMPAD 173

 Score = 29.3 bits (64), Expect(2) = 0.53,   Method: Compositional matrix adjust.
 Identities = 22/85 (25%), Positives = 33/85 (38%)
 Frame = +1

Query: 685 SPAEPKSPAEAKSPAEVKSPAEAKSPAEVKSPGEAKSPAAVKSPAEAKSPAAVKSPGEAK 744
            P  P  P    +P   + P     P    +PG   SP     P    SP     PG+  
Sbjct: 196 GPVSPGEPGNPDNPFSPRGPGRPLGPDTPLNPGSPPSPFMPGKPGRPPSPLGPGIPGKPG 375

Query: 745 SPGEAKSPAEAKSPAEAKSPIEVKS 769
            P    +P++ +SP    +P++V S
Sbjct: 376 RPSLPGTPSKPRSPF---APLKVSS 441

 Score = 22.7 bits (47), Expect(2) = 0.53,   Method: Compositional matrix adjust.
 Identities = 19/58 (32%), Positives = 21/58 (36%)
 Frame = +3

Query: 631 SPAEAKSPATVKSPGEAKSPSEAKSPAEAKSPAEAKSPAEAKSPAEVKSPGEAKSPAE 688
           SP    SP     PG   SPS    P     P     P  A SP    +PG    PA+
Sbjct: 3   SPFSPGSPGRPSGPGAPGSPSLPGRPGTPGFPWRPGRPCRA-SPGNPDTPGSPSMPAD 173

 Score = 32.7 bits (73), Expect = 0.77,   Method: Compositional matrix adjust.
 Identities = 24/74 (32%), Positives = 34/74 (45%)
 Frame = +1

Query: 553 SPGEAKSPAEPKSPAEPKSPAEAKSPAEPKSPATVKSPGEAKSPSEAKSPAEAKSPAEAK 612
           SPGE  +P  P SP  P  P    +P  P SP +   PG+   P    SP     P +  
Sbjct: 205 SPGEPGNPDNPFSPRGPGRPLGPDTPLNPGSPPSPFMPGK---PGRPPSPLGPGIPGKPG 375

Query: 613 SPAEAKSPAEAKSP 626
            P+   +P++ +SP
Sbjct: 376 RPSLPGTPSKPRSP 417

 Score = 26.6 bits (57), Expect(2) = 1.7,   Method: Compositional matrix adjust.
 Identities = 17/74 (22%), Positives = 26/74 (35%)
 Frame = +1

Query: 601 SPAEAKSPAEAKSPAEAKSPAEAKSPAEAKSPAEAKSPATVKSPGEAKSPSEAKSPAEAK 660
            P     P    +P   + P     P    +P    SP     PG   SP     P +  
Sbjct: 196 GPVSPGEPGNPDNPFSPRGPGRPLGPDTPLNPGSPPSPFMPGKPGRPPSPLGPGIPGKPG 375

Query: 661 SPAEAKSPAEAKSP 674
            P+   +P++ +SP
Sbjct: 376 RPSLPGTPSKPRSP 417

 Score = 23.5 bits (49), Expect(2) = 1.7,   Method: Compositional matrix adjust.
 Identities = 20/54 (37%), Positives = 24/54 (44%), Gaps = 2/54 (3%)
 Frame = +3

Query: 523 SPGEAKSPGEAKSPAEAKSPGEAKSPGEAKSPGEA--KSPAEPKSPAEPKSPAE 574
           SPG    PG   SP+    PG   +PG    PG     SP  P +P  P  PA+
Sbjct: 21  SPGRPSGPGAPGSPSL---PGRPGTPGFPWRPGRPCRASPGNPDTPGSPSMPAD 173

 Score = 29.6 bits (65), Expect = 6.2,   Method: Compositional matrix adjust.
 Identities = 19/74 (25%), Positives = 29/74 (39%)
 Frame = +1

Query: 637 SPATVKSPGEAKSPSEAKSPAEAKSPAEAKSPAEAKSPAEVKSPGEAKSPAEPKSPAEAK 696
            P +   PG   +P   + P     P    +P    SP     PG   SP  P  P +  
Sbjct: 196 GPVSPGEPGNPDNPFSPRGPGRPLGPDTPLNPGSPPSPFMPGKPGRPPSPLGPGIPGKPG 375

Query: 697 SPAEVKSPAEAKSP 710
            P+   +P++ +SP
Sbjct: 376 RPSLPGTPSKPRSP 417
>05987
          Length = 1726

 Score = 30.4 bits (67), Expect = 4.3,   Method: Compositional matrix adjust.
 Identities = 27/61 (44%), Positives = 36/61 (59%), Gaps = 1/61 (1%)
 Frame = -3

Query: 545  AKSPGEAKSPGEAKSPAEPKSPAEPKSPAEAKSPAEPKSPATVK-SPGEAKSPSEAKSPA 603
            +K PG+ ++P  AK  AEPK  AEPK  AE K  AEPK     K +P + K+ S+  SP 
Sbjct: 1370 SKKPGQKQTP--AKQKAEPKQKAEPKQKAEPKQKAEPKQTKEQKQTPAKNKNRSQQSSPK 1197

Query: 604  E 604
            +
Sbjct: 1196 Q 1194
>11942
          Length = 2252

 Score = 30.0 bits (66), Expect = 5.4,   Method: Compositional matrix adjust.
 Identities = 29/79 (36%), Positives = 44/79 (55%), Gaps = 3/79 (3%)
 Frame = +1

Query: 271 EIRAQLEGHAVQSTLQSEEWFRVRLDRLSEAAKVNTDAMRSAQEEITEYRRQLQARTT-- 328
           E+R QL+  +  S+   EE  R+RL R  +  K+ +D   S +EE T  ++  Q  T+  
Sbjct: 802 ELRQQLQSTSSTSSSHQEELERLRLQRTEDEKKI-SDLTSSLREEKTARKQSDQQMTSVQ 978

Query: 329 -ELEALKSTKESLERQRSE 346
            EL  LKST ++LER  +E
Sbjct: 979 EELADLKSTCDTLERNLNE 1035
>34682
          Length = 1030

 Score = 29.3 bits (64), Expect = 9.0,   Method: Composition-based stats.
 Identities = 28/107 (26%), Positives = 43/107 (40%), Gaps = 6/107 (5%)
 Frame = +3

Query: 273 RAQLEGHAVQSTLQSEEWFRVRLDRLSEAAKVNTDAMRSAQEEITEYRRQLQARTTELEA 332
           RA L G +V S   S +  +   D +   AK   D      EE+ EY      R TEL+ 
Sbjct: 402 RALLPGLSVTSISSSRQMRKYGRDDIDNIAK---DVEGKTPEEVIEYNAVFWERCTELQD 572

Query: 333 LKSTKESLERQRSELEDRHQ------ADIASYQDAIQQLDSELRNTK 373
           ++     +ER   +++ R          +A Y+    QL  +  N K
Sbjct: 573 IERIMGQIERGEGKIQRRLSIKKALDQKMARYRAPFHQLRLQYGNNK 713
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|20070404|ref|NP_613058.1| ubiquitin specific
peptidase 39 [Mus musculus]
         (564 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

07308                                                                  77   1e-14
03515                                                                  34   0.12 
10424                                                                  32   0.87 
11884                                                                  32   0.91 
34550                                                                  30   2.8  
09880                                                                  28   8.8  
>07308
          Length = 1767

 Score = 77.4 bits (189), Expect = 1e-14,   Method: Compositional matrix adjust.
 Identities = 33/46 (71%), Positives = 40/46 (86%)
 Frame = -2

Query: 511  GSYRIHVLHHGTGKWYELQDLQVTDILPQMITLSEAYIQIWKRRDN 556
            G+YR HVLH  TGKWYE+QDL V DILPQMITLSE+YIQI++ R++
Sbjct: 1754 GTYRCHVLHKATGKWYEMQDLHVADILPQMITLSESYIQIYELRED 1617
>03515
          Length = 2030

 Score = 34.3 bits (77), Expect = 0.12,   Method: Compositional matrix adjust.
 Identities = 23/79 (29%), Positives = 34/79 (43%)
 Frame = -1

Query: 479  LREYLSEEVQAVHKNTTYDLIANIVHDGKPSEGSYRIHVLHHGTGKWYELQDLQVTDILP 538
            L+ Y SE+         YDL A   H G    G Y +    +  GKWY   D    ++  
Sbjct: 2006 LKLYDSEDFTGAQ----YDLYAMSCHTGIMGGGHY-VAYSKNPNGKWYCYNDSSCKEVQE 1842

Query: 539  QMITLSEAYIQIWKRRDND 557
              +  + AYI  ++RR+ D
Sbjct: 1841 DQLDTNSAYILFYERRNID 1785
>10424
          Length = 343

 Score = 31.6 bits (70), Expect = 0.87,   Method: Composition-based stats.
 Identities = 26/95 (27%), Positives = 44/95 (46%), Gaps = 4/95 (4%)
 Frame = +3

Query: 80  DSEPEREVRAKNG----RVDSEDRRSRHCPYLDTINRSVLDFDFEKLCSISLSHINAYAC 135
           D++P+  + A        +   D ++RHC  L +++         ++CS+SLSH  A+ C
Sbjct: 69  DNDPQLSIHAHTHTLSLSLSRTDCKTRHC--LKSLSLE------NEVCSLSLSHT*AHTC 224

Query: 136 LVCGKYFQGRGLKSHAYIHSVQFSHHVFLNLHTLK 170
           +         G  +H  IHS     H+F+  H LK
Sbjct: 225 V---------GACAHILIHS-----HLFVCAH*LK 287
>11884
          Length = 952

 Score = 31.6 bits (70), Expect = 0.91,   Method: Compositional matrix adjust.
 Identities = 27/118 (22%), Positives = 49/118 (41%), Gaps = 2/118 (1%)
 Frame = +3

Query: 438 KRFQLTKLPPYLIFCIKRF--TKNNFFVEKNPTIVNFPITNVDLREYLSEEVQAVHKNTT 495
           KRF L K+P  L   + RF  T+    + K+   + FP   +++R+Y+S           
Sbjct: 228 KRFSLHKIPNVLTIQLNRFGFTRAAGKINKH---IQFP-EKLNVRQYMSRRQG---DPEY 386

Query: 496 YDLIANIVHDGKPSEGSYRIHVLHHGTGKWYELQDLQVTDILPQMITLSEAYIQIWKR 553
           Y L   ++H G      +    +      WY + D  V  +    +  S+AY+  + +
Sbjct: 387 YHLYGVLIHSGHHCNMGHYYCYVRSPANSWYIMNDSSVHQVSASRVFGSQAYLLFYTK 560
>34550
          Length = 405

 Score = 30.0 bits (66), Expect = 2.8,   Method: Composition-based stats.
 Identities = 16/40 (40%), Positives = 24/40 (60%), Gaps = 1/40 (2%)
 Frame = -2

Query: 281 RKLWNPRNFKAHVSPHEMLQAV-VLCSKKTFQITKQGDGV 319
           R+ ++PRN  AH +P+  LQA   L   +TF+  +  DGV
Sbjct: 311 RRSFHPRNRPAHDAPYRPLQAAEQLTYSRTFRXLQDDDGV 192
>09880
          Length = 893

 Score = 28.1 bits (61), Expect = 8.8,   Method: Compositional matrix adjust.
 Identities = 16/39 (41%), Positives = 20/39 (51%), Gaps = 3/39 (7%)
 Frame = -2

Query: 139 GKYFQGRGLKSHAYIH---SVQFSHHVFLNLHTLKFYCL 174
           G     +G  +H YI    S+ FSHH+ L   TL F CL
Sbjct: 682 GNQIVEQGTLTHTYIFNXASILFSHHIILCPLTLLFCCL 566
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|48976076|ref|NP_932136.2| centrosomal protein 78kDa
[Mus musculus]
         (790 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

26613                                                                  79   1e-14
19912                                                                  46   7e-05
34514                                                                  31   2.2  
>26613
          Length = 425

 Score = 78.6 bits (192), Expect = 1e-14,   Method: Compositional matrix adjust.
 Identities = 51/106 (48%), Positives = 67/106 (63%), Gaps = 7/106 (6%)
 Frame = -1

Query: 464 LQEKLEECLRQLKEERVIRLKADKRVSELEHENAQL----RNINFSLSEAL-HAQSLTNM 518
           LQ ++E+  R LKEER  R K+D RV +L  EN +L    R I    S A+  A      
Sbjct: 356 LQVEVEQMRRSLKEERQERAKSDNRVMQLMMENRRLEDDLRIIRLRQSSAVPGAGGRETS 177

Query: 519 ILDDEGVLGSIENSFQKFHAFLDLLKDAGLGQLATMAGI--DQSDF 562
           ++ DE VL SIE SF++FHAFLD+L++AGLG+L TMAG+  DQ  F
Sbjct: 176 VIHDESVLDSIEASFKQFHAFLDMLREAGLGELITMAGLAEDQMPF 39
>19912
          Length = 865

 Score = 45.8 bits (107), Expect = 7e-05,   Method: Compositional matrix adjust.
 Identities = 35/145 (24%), Positives = 68/145 (46%)
 Frame = +1

Query: 157 HLSLANCPIGDGGLEIICQGIKNSVTLKTVNFTGCNLTWQGACHMAKILKYQTMRRHEET 216
           ++ L++  +G+ G + +   I +++++K +N    +L  +GA  +A  +K          
Sbjct: 67  YVDLSHNNLGEAGGQHLGPAISDNISIKELNLAWNHLRRKGAVAVAAGVKTNVT------ 228

Query: 217 WAESLRYRRPDLDCMAGLRRITLNCNTLIGDQGASAFADSLSEDLWLRALDLQQCGLTSE 276
                            ++RI L+ N   G +GA A + ++ E+  L  LD+    +++E
Sbjct: 229 -----------------MKRINLSWNGF-GHEGAIALSSAVKENSVLEELDIMNNRISTE 354

Query: 277 GAKALLEALETNRTLVVLDIRKNPL 301
           GA  + + L  N TL V  I KNP+
Sbjct: 355 GAVLIGKGLSLNETLRVFKIGKNPM 429
>34514
          Length = 1178

 Score = 30.8 bits (68), Expect = 2.2,   Method: Compositional matrix adjust.
 Identities = 12/47 (25%), Positives = 26/47 (55%)
 Frame = -3

Query: 165 IGDGGLEIICQGIKNSVTLKTVNFTGCNLTWQGACHMAKILKYQTMR 211
            GD G++ +C G++N+ TL +++   C+L      ++  I+    +R
Sbjct: 372 FGDEGVKYLCDGLRNNTTLLSISLCYCDLGVASGTYLGSIVSTTAVR 232
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6679217|ref|NP_032812.1| protein-L-isoaspartate
(D-aspartate) O-methyltransferase 1 [Mus musculus]
         (227 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

27565                                                                  76   1e-14
09209                                                                  33   0.10 
17408                                                                  31   0.35 
12371                                                                  27   7.8  
>27565
          Length = 573

 Score = 75.9 bits (185), Expect = 1e-14,   Method: Compositional matrix adjust.
 Identities = 38/66 (57%), Positives = 49/66 (74%)
 Frame = +3

Query: 157 HVGAAAPVVPQALIDQLKPGGRLILPVGPAGGNQMLEQYDKLQDGSVKMKPLMGVIYVPL 216
           HVGAAA  +P  L++QL+PGGRLI+PV    G Q L Q DK  DG+V  + LMGV+YVPL
Sbjct: 120 HVGAAATSLPYTLVEQLRPGGRLIVPVERMVGGQALMQVDKGLDGTVSQQELMGVMYVPL 299

Query: 217 TDKEKQ 222
           T+K++Q
Sbjct: 300 TNKDQQ 317
>09209
          Length = 1416

 Score = 33.1 bits (74), Expect = 0.10,   Method: Compositional matrix adjust.
 Identities = 29/111 (26%), Positives = 51/111 (45%), Gaps = 7/111 (6%)
 Frame = +2

Query: 78  EGAKALDVGSGSGILTACFARMVGNSGKVIGIDHIKELVDDSITNVKKDDPMLLSSGRVR 137
           +G   +DVGSG GIL+   AR+      VIG+D  +E +  +  ++  D  +  +   ++
Sbjct: 116 DGFHIVDVGSGGGILSEPLARL---GASVIGVDASEENIKTAQAHMINDPKVARNITYIQ 286

Query: 138 LVVGDGRMGYAEEAPYDAI-------HVGAAAPVVPQALIDQLKPGGRLIL 181
             V D  +   +   +DA+       HV   +  +  A    +KPGG + L
Sbjct: 287 STVED--LVATQAGKFDAVVASEVVEHVADVSTFI-TACCQLVKPGGSIFL 430
>17408
          Length = 712

 Score = 31.2 bits (69), Expect = 0.35,   Method: Compositional matrix adjust.
 Identities = 22/65 (33%), Positives = 33/65 (50%), Gaps = 2/65 (3%)
 Frame = +1

Query: 75  QLHEGAKALDVGSGSGILTACFARMVGNSGKVIGID--HIKELVDDSITNVKKDDPMLLS 132
            L +G   LDVG G+GIL+  FA   G + KVI +D  +I E     I +    D + + 
Sbjct: 16  HLFQGKTVLDVGCGTGILSM-FAAKAG-AAKVIAVDCSNIIEFARQVIIDNNLQDIITVV 189

Query: 133 SGRVR 137
            G++ 
Sbjct: 190 KGKIE 204
>12371
          Length = 1202

 Score = 26.6 bits (57), Expect = 7.8,   Method: Compositional matrix adjust.
 Identities = 15/48 (31%), Positives = 26/48 (54%)
 Frame = +3

Query: 9   SHSELIHNLRKNGIIKTDKVFEVMLATDRSHYAKSNPYMDSPQSTGFQ 56
           S   +I  L+ N  +KTDKVF++++   + H  K   +  +P  T F+
Sbjct: 396 SEKLIIFGLKSN--LKTDKVFDLLILLAKFHIFKCKLHNINPNITIFK 533
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|225637531|ref|NP_079620.2| eukaryotic translation
initiation factor 3, subunit F [Mus musculus]
         (361 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

20649                                                                  76   2e-14
14533                                                                  65   5e-11
09316                                                                  44   1e-04
13866                                                                  39   0.004
24092                                                                  31   0.73 
>20649
          Length = 549

 Score = 75.9 bits (185), Expect = 2e-14,   Method: Compositional matrix adjust.
 Identities = 39/118 (33%), Positives = 68/118 (57%), Gaps = 5/118 (4%)
 Frame = -3

Query: 96  VRLHPVILASIVDSYERRNE--GAARVIGTLLGTVDKHSVEVTNCFSVPHNESEDEVAV- 152
           V +HP++L S+VD + R  +     RV+G LLG      ++V+N F+VP +E + +  V 
Sbjct: 379 VVVHPLVLLSVVDHFNRMGKVGNVKRVVGVLLGANKGGILDVSNSFAVPFDEDDKDRNVW 200

Query: 153 --DMEFAKNMYELHKKVSPNELILGWYATGHDITEHSVLIHEYYSREAPNPIHLTVDT 208
             D ++ +NMY + KKV+  E ++GWY TG  +  + + I+E   +  PN + + +D 
Sbjct: 199 FLDHDYLENMYGMFKKVNAREKVVGWYHTGPKLHHNDIAINEMIRKYCPNSVLVVIDA 26
>14533
          Length = 1436

 Score = 65.1 bits (157), Expect = 5e-11,   Method: Compositional matrix adjust.
 Identities = 57/238 (23%), Positives = 107/238 (44%), Gaps = 16/238 (6%)
 Frame = -2

Query: 139  FSVPHNESEDEVAV---DMEFAKNMYELHKKVSPNELILGWYATGHDITEHSVLIHEYYS 195
            F  P +E + +  V   D ++ +NMY + KKV+  E ++GWY TG  +  + + I+E   
Sbjct: 1306 FFSPFDEDDKDRNVWFLDHDYLENMYGMFKKVNAREKVVGWYHTGPKLHHNDIAINEMIR 1127

Query: 196  REAPNPIHLTVDTGLQHGRMSIKAYVS-------------TLMGVPGRTMGVMFTPLTVK 242
            +  PN + + +D   +   +  + Y++             T   VP          + V+
Sbjct: 1126 KYCPNSVLVVIDAKPKDLGLPTEGYIAVEEVHDDGSPTTKTFDHVPSDIGAEEAEEVGVE 947

Query: 243  YAYYDTERIGVDLIMKTCFSPNRVIGLSSDLQQVGGASARIQDALSTVLQYAEDVLSGKV 302
            +   D +   V  + +          ++S L  + G  + I++  S    Y   V+SGK+
Sbjct: 946  HLLRDIKDTTVGTLSQR---------ITSQLMGLKGLHSHIREIDS----YVGKVVSGKL 806

Query: 303  SADNTVGRFLMSLVNQVPKIVPDDFETMLNSNINDLLMVTYLANLTQSQIALNEKLVN 360
              ++ V   L  + N +P +   DF   ++   ND ++V YLA+L +S IAL+  + N
Sbjct: 805  PINHQVVYLLQDIFNLLPDVKLADFVRSMHIKTNDQMLVVYLASLIRSVIALHNLIDN 632
>09316
          Length = 2312

 Score = 43.5 bits (101), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 26/79 (32%), Positives = 39/79 (49%)
 Frame = -3

Query: 101 VILASIVDSYERRNEGAARVIGTLLGTVDKHSVEVTNCFSVPHNESEDEVAVDMEFAKNM 160
           V L  I  S E    G   V G LLG V  + +E+TNCF  P +  ED+   ++ +   M
Sbjct: 612 VALKIIKHSQEESAGGTDLVQGMLLGLVVDNRLEITNCFPFPRHSEEDDFD-EVNYPMEM 436

Query: 161 YELHKKVSPNELILGWYAT 179
               + V+ + L +GWY +
Sbjct: 435 MRYLRHVNIDHLNVGWYQS 379
>13866
          Length = 855

 Score = 38.5 bits (88), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 21/61 (34%), Positives = 36/61 (59%), Gaps = 2/61 (3%)
 Frame = -2

Query: 119 RVIGTLLGT-VDKHSVEVTNCFSVPHNESEDEV-AVDMEFAKNMYELHKKVSPNELILGW 176
            V+G +LG  VD ++V V + F++P + +   V AVD  F   M ++ K+    E+++GW
Sbjct: 635 EVMGLMLGEFVDDYTVRVIDVFAMPQSGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGW 456

Query: 177 Y 177
           Y
Sbjct: 455 Y 453
>24092
          Length = 628

 Score = 31.2 bits (69), Expect = 0.73,   Method: Compositional matrix adjust.
 Identities = 18/64 (28%), Positives = 28/64 (43%)
 Frame = +3

Query: 210 LQHGRMSIKAYVSTLMGVPGRTMGVMFTPLTVKYAYYDTERIGVDLIMKTCFSPNRVIGL 269
           ++H R   K +  T +     T+   +TP T  Y Y     I ++ I   CF P+R +  
Sbjct: 126 IRHARFFFKKF*FTQIQQYKHTLKHTYTPYTHTYIYTYFTHIHINQIKSCCFKPSRPLWA 305

Query: 270 SSDL 273
            S L
Sbjct: 306 ISRL 317
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|27369784|ref|NP_766142.1| zinc finger, DHHC domain
containing 17 [Mus musculus]
         (622 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

11289                                                                  77   2e-14
05924                                                                  76   4e-14
09292                                                                  74   2e-13
13462                                                                  70   2e-12
19166                                                                  64   1e-10
14005                                                                  60   2e-09
11295                                                                  54   2e-07
00540                                                                  54   2e-07
06253                                                                  53   5e-07
20792                                                                  50   3e-06
02114                                                                  49   7e-06
02055                                                                  48   1e-05
34789                                                                  48   1e-05
21532                                                                  47   2e-05
30978                                                                  47   2e-05
20036                                                                  47   2e-05
33144                                                                  45   8e-05
25470                                                                  45   1e-04
03590                                                                  44   2e-04
17277                                                                  43   3e-04
12417                                                                  42   5e-04
08473                                                                  42   8e-04
16561                                                                  41   0.001
15772                                                                  40   0.003
09214                                                                  40   0.003
28691                                                                  38   0.010
38834                                                                  38   0.010
28494                                                                  38   0.011
08755                                                                  37   0.031
28113                                                                  36   0.055
21751                                                                  36   0.055
20884                                                                  35   0.077
13900                                                                  35   0.093
30463                                                                  35   0.10 
22269                                                                  34   0.16 
27108                                                                  34   0.17 
11861                                                                  34   0.20 
25464                                                                  33   0.43 
04513                                                                  32   0.65 
30217                                                                  32   0.86 
15359                                                                  32   1.1  
28491                                                                  30   2.2  
09370                                                                  30   3.0  
21550                                                                  29   4.5  
>11289
          Length = 2333

 Score = 77.0 bits (188), Expect = 2e-14,   Method: Compositional matrix adjust.
 Identities = 35/93 (37%), Positives = 50/93 (53%)
 Frame = +1

Query: 399 DPGIIKATEEQKKKTIVELAETGSLDLSIFCSTCLIRKPVRSKHCGVCNRCIAKFDHHCP 458
            PG  +     K     E+   G +    +C TC + +P R+ HC +C+ C+ +FDHHCP
Sbjct: 595 SPGTYRPPPRTK-----EIVIKGQVVKLKYCFTCKLFRPPRASHCSLCDNCVERFDHHCP 759

Query: 459 WVGNCVGAGNHRYFMGYXXXXXXMICWMIYGCV 491
           WVGNCVG  N+RYF  +      + C  I+ CV
Sbjct: 760 WVGNCVGKRNYRYFYLF-ILSLSVHCIYIFACV 855
>05924
          Length = 704

 Score = 76.3 bits (186), Expect = 4e-14,   Method: Compositional matrix adjust.
 Identities = 61/183 (33%), Positives = 90/183 (49%)
 Frame = +1

Query: 60  YERCRELVEAGYDVRQPDKENVTLLHWAAINNRIDLVKYYISKGAIVDQLGGDLNSTPLH 119
           ++  + LV+ G DV      + TLLH A      DLV+  I  GA  +    D   T LH
Sbjct: 4   HKAVQRLVKGGVDVNARFWYDSTLLHEAVSMASEDLVQMLIKAGANANSTNQD-GRTALH 180

Query: 120 WATRQGHLSMVVQLMKYGADPSLIDGEGCSCIHLAAQFGHTSIVAYLIAKGQDVDMMDQN 179
            A R G+ ++V  L+  G D +    +G +C+H+A   GHT +V  L+  G DV++ D  
Sbjct: 181 LACRGGYTNIVQILIAAGTDVNRRTVDGKTCLHVAVWRGHTEVVVKLVNAGADVNIPDSV 360

Query: 180 GMTPLMWAAYRTHSVDPTRLLLTFNVSVNLGDKYHKNTALHWAVLAGNTTVISLLLEAGG 239
           G +PL WAA   ++   T +L+     VN   K  K T LH A+  G+  V+  LL  G 
Sbjct: 361 GCSPLYWAARSNYTAILT-VLVNAGAKVNYRVKS-KWTPLHAALHLGHMGVVRYLLLQGA 534

Query: 240 NVD 242
             +
Sbjct: 535 ETN 543

 Score = 50.4 bits (119), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 46/187 (24%), Positives = 78/187 (41%), Gaps = 35/187 (18%)
 Frame = +1

Query: 66  LVEAGYDVRQPDKENVTLLHWAAINNRIDLVKYYISKGAIVDQLGGDLNSTPLHWATRQG 125
           L++AG +    +++  T LH A      ++V+  I+ G  V++   D   T LH A  +G
Sbjct: 121 LIKAGANANSTNQDGRTALHLACRGGYTNIVQILIAAGTDVNRRTVD-GKTCLHVAVWRG 297

Query: 126 HLSMVVQLMKYGADPSLIDGEGCSCI---------------------------------H 152
           H  +VV+L+  GAD ++ D  GCS +                                 H
Sbjct: 298 HTEVVVKLVNAGADVNIPDSVGCSPLYWAARSNYTAILTVLVNAGAKVNYRVKSKWTPLH 477

Query: 153 LAAQFGHTSIVAYLIAKGQDVDM--MDQNGMTPLMWAAYRTHSVDPTRLLLTFNVSVNLG 210
            A   GH  +V YL+ +G + ++   D+  ++ LM   + +H      L +      NL 
Sbjct: 478 AALHLGHMGVVRYLLLQGAETNITVQDKTVVSLLMDNEHLSHKERERTLAMLVKAGYNL- 654

Query: 211 DKYHKNT 217
              HK+T
Sbjct: 655 ---HKDT 666

 Score = 42.0 bits (97), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 30/87 (34%), Positives = 46/87 (52%), Gaps = 2/87 (2%)
 Frame = +1

Query: 58  GIYERCRELVEAGYDVRQPDKENVTLLHWAAINNRIDLVKYYISKGAIVDQLGGDLNS-- 115
           G  E   +LV AG DV  PD    + L+WAA +N   ++   ++ GA V+     + S  
Sbjct: 295 GHTEVVVKLVNAGADVNIPDSVGCSPLYWAARSNYTAILTVLVNAGAKVNY---RVKSKW 465

Query: 116 TPLHWATRQGHLSMVVQLMKYGADPSL 142
           TPLH A   GH+ +V  L+  GA+ ++
Sbjct: 466 TPLHAALHLGHMGVVRYLLLQGAETNI 546
>09292
          Length = 1486

 Score = 73.6 bits (179), Expect = 2e-13,   Method: Compositional matrix adjust.
 Identities = 55/228 (24%), Positives = 103/228 (45%), Gaps = 32/228 (14%)
 Frame = -2

Query: 64   RELVEAGYDVRQPDKENVTLLHWAAINNRIDLVKYYISKGAIVDQLGGDLNSTPLHWATR 123
             ELV  G D    DK+++T +  A + N  D+V+Y +  GA  +       + P+  A +
Sbjct: 1212 EELVRHGADFNAEDKDHLTPVFNACVKNDTDIVRYLLESGARANT-----TARPIFHAVK 1048

Query: 124  QGHLSMVVQLMKYGADPSLIDGEGCSCIHLAAQFGHTSIVAYLIAKGQDVDMMDQNGMTP 183
             G+  +V  L+ +GA  + + G   S +H+A + G+  +   +I  G +V+ +D++G TP
Sbjct: 1047 YGYSEIVQLLLVHGAAVNSLPGTK-SPLHIACRNGNIEMARTVIIAGANVNAVDKDGNTP 871

Query: 184  LMWAAYRTHSVDPTRLLLTFNVSVNLGDKYHKN--------------------------- 216
            L  +     S    RLL+ F  +V  G+   +                            
Sbjct: 870  LHISVRAPSSAQLVRLLIRFGANVKWGNDNQQIPLHLACLYSNLETARLLLHCGSCSNEL 691

Query: 217  -----TALHWAVLAGNTTVISLLLEAGGNVDAQNVKGESALDLAKQRK 259
                 T LH+AV+ GN  ++ L+L+   +V++ + +  + L LA  ++
Sbjct: 690  SSKLWTPLHYAVIGGNVDIVRLVLQGSSDVNSPDGRNNAPLHLACMKQ 547

 Score = 53.1 bits (126), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 53/204 (25%), Positives = 90/204 (44%), Gaps = 2/204 (0%)
 Frame = -2

Query: 54   ATQYGIYERCRELVEAGYDVRQPDKENVTLLHWAAINNRIDLVKYYISKGAIVDQLGGDL 113
            A Q    E     ++ G  V   D  + T LH       + +    +   A V+    ++
Sbjct: 1440 AXQLQDVETLLAYLDIGMHVDTRDSHHETALHAVCYVGSVKMASVLLKHXADVNARN-NV 1264

Query: 114  NSTPLHWATRQGHLSMVVQLMKYGADPSLIDGEGCSCIHLAAQFGHTSIVAYLIAKGQDV 173
            + TPLH    +GHL +V +L+++GAD +  D +  + +  A     T IV YL+  G   
Sbjct: 1263 DRTPLHIXAIEGHLGLVEELVRHGADFNAEDKDHLTPVFNACVKNDTDIVRYLLESGARA 1084

Query: 174  DMMDQNGMTPLMWAAYRTHSVDPTRLLLTFNVSVNL--GDKYHKNTALHWAVLAGNTTVI 231
            +   +    P+  A    +S +  +LLL    +VN   G K    + LH A   GN  + 
Sbjct: 1083 NTTAR----PIFHAVKYGYS-EIVQLLLVHGAAVNSLPGTK----SPLHIACRNGNIEMA 931

Query: 232  SLLLEAGGNVDAQNVKGESALDLA 255
              ++ AG NV+A +  G + L ++
Sbjct: 930  RTVIIAGANVNAVDKDGNTPLHIS 859

 Score = 45.8 bits (107), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 33/124 (26%), Positives = 61/124 (49%)
 Frame = -2

Query: 64  RELVEAGYDVRQPDKENVTLLHWAAINNRIDLVKYYISKGAIVDQLGGDLNSTPLHWATR 123
           R L+  G +V+  +      LH A + + ++  +  +  G+  ++L   L  TPLH+A  
Sbjct: 828 RLLIRFGANVKWGNDNQQIPLHLACLYSNLETARLLLHCGSCSNELSSKL-WTPLHYAVI 652

Query: 124 QGHLSMVVQLMKYGADPSLIDGEGCSCIHLAAQFGHTSIVAYLIAKGQDVDMMDQNGMTP 183
            G++ +V  +++  +D +  DG   + +HLA       I   L+  G +V++   NG TP
Sbjct: 651 GGNVDIVRLVLQGSSDVNSPDGRNNAPLHLACMKQCIGIARCLLRHGANVNVSGYNGRTP 472

Query: 184 LMWA 187
           L  A
Sbjct: 471 LHIA 460

 Score = 41.6 bits (96), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 33/139 (23%), Positives = 64/139 (46%)
 Frame = -2

Query: 54  ATQYGIYERCRELVEAGYDVRQPDKENVTLLHWAAINNRIDLVKYYISKGAIVDQLGGDL 113
           A  Y   E  R L+  G    +   +  T LH+A I   +D+V+  +   + V+   G  
Sbjct: 759 ACLYSNLETARLLLHCGSCSNELSSKLWTPLHYAVIGGNVDIVRLVLQGSSDVNSPDGR- 583

Query: 114 NSTPLHWATRQGHLSMVVQLMKYGADPSLIDGEGCSCIHLAAQFGHTSIVAYLIAKGQDV 173
           N+ PLH A  +  + +   L+++GA+ ++    G + +H+A    +  +V  L   G + 
Sbjct: 582 NNAPLHLACMKQCIGIARCLLRHGANVNVSGYNGRTPLHIAISHHNLELVLLLYMCGAND 403

Query: 174 DMMDQNGMTPLMWAAYRTH 192
            ++D +G  P  ++    H
Sbjct: 402 QLVDFDGNFPSCYSMCHIH 346
>13462
          Length = 1388

 Score = 70.1 bits (170), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 55/163 (33%), Positives = 81/163 (49%), Gaps = 2/163 (1%)
 Frame = +3

Query: 81  VTLLHWAAINNRIDLVKYYISKGAIVDQLGGDLNSTPLHWATR--QGHLSMVVQLMKYGA 138
           +TLL  A   NR DLV   + +GA+ D     LN  PLH+A+    G+L +V  L+ YGA
Sbjct: 78  LTLLCVACKLNRADLVPVLLQRGALPDLPSLYLNKRPLHYASHHSNGNLGIVSMLLAYGA 257

Query: 139 DPSLIDGEGCSCIHLAAQFGHTSIVAYLIAKGQDVDMMDQNGMTPLMWAAYRTHSVDPTR 198
            P++ D +G + +HLA    +  +V  L+  G DV + D +  TPL+ A    +SV+   
Sbjct: 258 QPNVQDEDGNTALHLACSESNVDVVRLLLEWGGDVAVADIDNETPLVRACL-ANSVELVD 434

Query: 199 LLLTFNVSVNLGDKYHKNTALHWAVLAGNTTVISLLLEAGGNV 241
           LLL      N    +     L   V A +   + LL+ AG  V
Sbjct: 435 LLLHAGSDPN----HSHGRPLEIVVRAPSLESLKLLIGAGAQV 551

 Score = 43.5 bits (101), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 35/128 (27%), Positives = 63/128 (49%), Gaps = 2/128 (1%)
 Frame = +3

Query: 145 GEGCSCIHLAAQFGHTSIVAYLIAKGQDVDMMDQN-GMTPLMWAAYRTH-SVDPTRLLLT 202
           G G + + +A +     +V  L+ +G   D+        PL +A++ ++ ++    +LL 
Sbjct: 69  GNGLTLLCVACKLNRADLVPVLLQRGALPDLPSLYLNKRPLHYASHHSNGNLGIVSMLLA 248

Query: 203 FNVSVNLGDKYHKNTALHWAVLAGNTTVISLLLEAGGNVDAQNVKGESALDLAKQRKNVW 262
           +    N+ D+   NTALH A    N  V+ LLLE GG+V   ++  E+ L  A    +V 
Sbjct: 249 YGAQPNVQDE-DGNTALHLACSESNVDVVRLLLEWGGDVAVADIDNETPLVRACLANSVE 425

Query: 263 MINHLQEA 270
           +++ L  A
Sbjct: 426 LVDLLLHA 449

 Score = 35.4 bits (80), Expect = 0.061,   Method: Compositional matrix adjust.
 Identities = 29/94 (30%), Positives = 47/94 (50%), Gaps = 2/94 (2%)
 Frame = +3

Query: 54  ATQYGIYERCRELVEAGYDVRQPDKENVTLLHWAAINNRI--DLVKYYISKGAIVDQLGG 111
           A+++   +  + L   G DV    +  +T LH A I+     D V+  +  G+  + + G
Sbjct: 576 ASEHNYLDMMKVLHNYGVDVNGTGRLGLTALHHACISQEATHDAVRLLLLWGSNPNLVTG 755

Query: 112 DLNSTPLHWATRQGHLSMVVQLMKYGADPSLIDG 145
               TPLH+A +   +S V  L+ YGAD + IDG
Sbjct: 756 T-GDTPLHFACQTFAVSKVRLLLMYGADVNQIDG 854
>19166
          Length = 447

 Score = 64.3 bits (155), Expect = 1e-10,   Method: Composition-based stats.
 Identities = 43/127 (33%), Positives = 66/127 (51%)
 Frame = +1

Query: 82  TLLHWAAINNRIDLVKYYISKGAIVDQLGGDLNSTPLHWATRQGHLSMVVQLMKYGADPS 141
           T LH A   NRI +V+  +  GA +D    +   TPLH ++  GH+++V+ L+++ A P 
Sbjct: 64  TPLHIACKKNRIKVVELLLKYGASIDATT-ESGLTPLHVSSFMGHMNIVIYLIQHNAYPD 240

Query: 142 LIDGEGCSCIHLAAQFGHTSIVAYLIAKGQDVDMMDQNGMTPLMWAAYRTHSVDPTRLLL 201
                G + +HLAA+   T I+  L+  G  VD   +   TPL  A+ R  +VD   LLL
Sbjct: 241 TPTVRGETSLHLAARANQTDIIRILLRNGAAVDARAREQQTPLHIAS-RLGNVDNVVLLL 417

Query: 202 TFNVSVN 208
               S +
Sbjct: 418 QHGASAD 438

 Score = 52.4 bits (124), Expect = 5e-07,   Method: Composition-based stats.
 Identities = 40/146 (27%), Positives = 61/146 (41%)
 Frame = +1

Query: 116 TPLHWATRQGHLSMVVQLMKYGADPSLIDGEGCSCIHLAAQFGHTSIVAYLIAKGQDVDM 175
           TPLH A ++  + +V  L+KYGA        G + +H+++  GH +IV YLI      D 
Sbjct: 64  TPLHIACKKNRIKVVELLLKYGASIDATTESGLTPLHVSSFMGHMNIVIYLIQHNAYPD- 240

Query: 176 MDQNGMTPLMWAAYRTHSVDPTRLLLTFNVSVNLGDKYHKNTALHWAVLAGNTTVISLLL 235
                 TP +                               T+LH A  A  T +I +LL
Sbjct: 241 ------TPTV----------------------------RGETSLHLAARANQTDIIRILL 318

Query: 236 EAGGNVDAQNVKGESALDLAKQRKNV 261
             G  VDA+  + ++ L +A +  NV
Sbjct: 319 RNGAAVDARAREQQTPLHIASRLGNV 396
>14005
          Length = 1745

 Score = 60.5 bits (145), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 60/220 (27%), Positives = 106/220 (48%), Gaps = 3/220 (1%)
 Frame = -1

Query: 51   IVKATQYGIYERCRELVEA-GYDVRQPDKENVTLLHWAAINNRIDLVKYYISKGAIVDQL 109
            ++ A++ G      EL++  G DV + D++    L++A + N I+LVK  +  GA V+  
Sbjct: 1733 LIIASRMGHLAVVSELLKVPGIDVNERDEKLRPALYFACMGNDIELVKQLVRYGARVNAY 1554

Query: 110  GGDLNSTPLHWATRQGHLSMVVQLMKYGADPSLIDGEGCSCIHLAAQFGHTSIVAYLIAK 169
              +   TP H   ++G   + + L+++GA+      +G + + +A +     +   LI  
Sbjct: 1553 STETWWTPFHACCKRGDPRIALYLLRHGANKESRTVDGKTPLVVACKNDKAEVALLLIRS 1374

Query: 170  GQDVDMM-DQNGMTPLMWAAYRTHSVDPTRLLLTFNVSVNLGDKYHKNTALHWAVLAG-N 227
            G +V++  D    TP+ +A  R +     RL+L          K H  TALH A + G  
Sbjct: 1373 GANVNVSCDITANTPVHFACQRPNIELLKRLVLHGADVDKPNAKGH--TALHVASVRGFK 1200

Query: 228  TTVISLLLEAGGNVDAQNVKGESALDLAKQRKNVWMINHL 267
              VI LL      V+A  +KG +AL +A + K+  ++  L
Sbjct: 1199 QHVIYLLDFCDAEVNAATLKGNNALHIACRGKHADLVELL 1080

 Score = 50.4 bits (119), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 46/179 (25%), Positives = 72/179 (40%), Gaps = 35/179 (19%)
 Frame = -1

Query: 115  STPLHWATRQGHLSMVVQLMK----------------------------------YGADP 140
             TPL  A+R GHL++V +L+K                                  YGA  
Sbjct: 1742 ETPLIIASRMGHLAVVSELLKVPGIDVNERDEKLRPALYFACMGNDIELVKQLVRYGARV 1563

Query: 141  SLIDGEG-CSCIHLAAQFGHTSIVAYLIAKGQDVDMMDQNGMTPLMWAAYRTHSVDPTRL 199
            +    E   +  H   + G   I  YL+  G + +    +G TPL+  A +    +   L
Sbjct: 1562 NAYSTETWWTPFHACCKRGDPRIALYLLRHGANKESRTVDGKTPLV-VACKNDKAEVALL 1386

Query: 200  LLTFNVSVNLGDKYHKNTALHWAVLAGNTTVISLLLEAGGNVDAQNVKGESALDLAKQR 258
            L+    +VN+      NT +H+A    N  ++  L+  G +VD  N KG +AL +A  R
Sbjct: 1385 LIRSGANVNVSCDITANTPVHFACQRPNIELLKRLVLHGADVDKPNAKGHTALHVASVR 1209
>11295
          Length = 1179

 Score = 53.9 bits (128), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 39/140 (27%), Positives = 72/140 (51%), Gaps = 6/140 (4%)
 Frame = +1

Query: 42  HIDDYSTWDIVKATQYGIYER-CRELVEAGYDVRQPDK-----ENVTLLHWAAINNRIDL 95
           H  D++  D  + T +    R CR L    + V  PD       +++    A +    ++
Sbjct: 442 HNADHTIRDAAEFTPFHCAIRYCRVLAVKTFLVWFPDLIHSFYNDLSPTFMACLQCDKEM 621

Query: 96  VKYYISKGAIVDQLGGDLNSTPLHWATRQGHLSMVVQLMKYGADPSLIDGEGCSCIHLAA 155
           +   I  GA V+      + TPLH+ +R+GHL+M+  L++  A+P+++D EG + +++A+
Sbjct: 622 LSLLIKFGASVN-CADHYHYTPLHYISRRGHLTMLQLLLQGKAEPNVVDDEGITPLYIAS 798

Query: 156 QFGHTSIVAYLIAKGQDVDM 175
             GH +IV  L+  G  + M
Sbjct: 799 CEGHVTIVNILLQSGAKIYM 858

 Score = 50.1 bits (118), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 57/236 (24%), Positives = 96/236 (40%), Gaps = 35/236 (14%)
 Frame = +1

Query: 70  GYDVRQPDKENVTLLHWAAINNRIDLVKYYISKGAIVDQLGGDLNSTPLH---WATRQGH 126
           G  V     ++VT LH A   +  ++    +  GA    L   +  TPLH   W   +G 
Sbjct: 145 GIAVNATSNDHVTALHIACCLDDREMASLLLKYGAYAMALDV-IGHTPLHVACWCGSEGV 321

Query: 127 LSMVVQLMKYGADPSLIDGEGCSCIHLAAQFGHTSIVAYLIAKGQDVDMMDQNGMTP--- 183
             +++   +   D + +D +G   + LA++ G   I+  L+    D  + D    TP   
Sbjct: 322 TRLLLD--RSDVDVNALDHDGKXPLRLASECGFHYIIRQLLYHNADHTIRDAAEFTPFHC 495

Query: 184 -------------LMWAAYRTHS----VDPT------------RLLLTFNVSVNLGDKYH 214
                        L+W     HS    + PT             LL+ F  SVN  D YH
Sbjct: 496 AIRYCRVLAVKTFLVWFPDLIHSFYNDLSPTFMACLQCDKEMLSLLIKFGASVNCADHYH 675

Query: 215 KNTALHWAVLAGNTTVISLLLEAGGNVDAQNVKGESALDLAKQRKNVWMINHLQEA 270
             T LH+    G+ T++ LLL+     +  + +G + L +A    +V ++N L ++
Sbjct: 676 Y-TPLHYISRRGHLTMLQLLLQGKAEPNVVDDEGITPLYIASCEGHVTIVNILLQS 840

 Score = 40.8 bits (94), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 33/128 (25%), Positives = 56/128 (43%), Gaps = 5/128 (3%)
 Frame = +1

Query: 66  LVEAGYDVRQPDKENVTLLHWAAINNRIDLVKYYIS----KGAIVDQLGGDLNSTPLHWA 121
           L++ G  +   D   ++ LH A I    ++ +  +      G  V+    D + T LH A
Sbjct: 22  LLQGGAQIYWTDHRGLSALHHACIGRNTEVAELLLDGWNGDGIAVNATSND-HVTALHIA 198

Query: 122 TRQGHLSMVVQLMKYGADPSLIDGEGCSCIHLAAQFGHTSIVAYLIAKGQ-DVDMMDQNG 180
                  M   L+KYGA    +D  G + +H+A   G   +   L+ +   DV+ +D +G
Sbjct: 199 CCLDDREMASLLLKYGAYAMALDVIGHTPLHVACWCGSEGVTRLLLDRSDVDVNALDHDG 378

Query: 181 MTPLMWAA 188
             PL  A+
Sbjct: 379 KXPLRLAS 402

 Score = 39.7 bits (91), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 47/215 (21%), Positives = 91/215 (42%), Gaps = 5/215 (2%)
 Frame = +1

Query: 54  ATQYGIYERCRELVEAGYDVRQPDKENVTLLHWAAINNRIDLVKYYIS-KGAIVDQLGGD 112
           A++ G +   R+L+    D    D    T  H A    R+  VK ++     ++     D
Sbjct: 397 ASECGFHYIIRQLLYHNADHTIRDAAEFTPFHCAIRYCRVLAVKTFLVWFPDLIHSFYND 576

Query: 113 LNSTPLHWATRQGHLSMVVQLMKYGADPSLIDGEGCSCIHLAAQFGHTSIVAYLIAKGQD 172
           L  +P   A  Q    M+  L+K+GA  +  D    + +H  ++ GH +++  L+    +
Sbjct: 577 L--SPTFMACLQCDKEMLSLLIKFGASVNCADHYHYTPLHYISRRGHLTMLQLLLQGKAE 750

Query: 173 VDMMDQNGMTPLMWAAYRTHSVDPTRLLLTFNVSVNLGDKYHKNTA---LHWAVLAGNTT 229
            +++D  G+TPL  A+   H       +   N+ +  G K +   A   +H A  AG+  
Sbjct: 751 PNVVDDEGITPLYIASCEGH-------VTIVNILLQSGAKIYMPCARDPVHAACKAGHEV 909

Query: 230 VISLLLE-AGGNVDAQNVKGESALDLAKQRKNVWM 263
           +     +  G  ++A+ V       +A   + ++M
Sbjct: 910 IALRFFDFLGEKLNAKGVCSTMCRSVALAIRRLYM 1014
>00540
          Length = 3034

 Score = 53.9 bits (128), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 48/184 (26%), Positives = 85/184 (46%), Gaps = 11/184 (5%)
 Frame = -2

Query: 101  SKGAIVDQLGGDLNSTPLHWATRQGHLSMVVQLMKYGADPSLIDGEGCSCIHLAAQFGHT 160
            +KGA V+Q     NSTPL  A   GHL +V  L+++ A+  + +  G +C+ +A   GH 
Sbjct: 3006 AKGAEVNQTTRS-NSTPLRAACYDGHLEVVQFLVEHKAEIEIANSHGHTCLMIACYRGHL 2830

Query: 161  SIVAYLIAKGQDVDMMDQNGMTPLMWAAYRTHSVDPTRLLLTFNVSVNLGDKYHKNTALH 220
             +V YL+  G  V+     G T L  +A  +  +   +LLL+      +    +  T L 
Sbjct: 2829 DVVEYLLYLGAQVNRRSVKGNTALHDSA-ESGKLSIMKLLLS--KGAKMAKDAYGQTPLS 2659

Query: 221  WAVLAGNTTVISLLLEA-----GGNVDAQNVKGESALDLAKQRKNVWMIN------HLQE 269
             A + G+  ++  L+       G   +A  + G + +D  K R +   +       HL++
Sbjct: 2658 AAAMTGHEEIVRYLISGPLFTPGEQANALELMGATLVD--KSRDHAGAVKLWTKALHLRK 2485

Query: 270  ARQA 273
             ++A
Sbjct: 2484 TKEA 2473
>06253
          Length = 1049

 Score = 52.8 bits (125), Expect = 5e-07,   Method: Compositional matrix adjust.
 Identities = 51/197 (25%), Positives = 91/197 (46%), Gaps = 2/197 (1%)
 Frame = -1

Query: 54   ATQYGIYERCRELVEAGYDVRQPDKENVTLLHWAAINNRIDLVKYYISKGAIVDQLGGDL 113
            A  +G  +    L+E G +V   D   +  LH A      ++V+  +  GA  +    + 
Sbjct: 1025 AAGFGRKDVVEHLLENGANVHARDDGGLIPLHNACSFGHAEVVQLLLRHGADPNARD-NW 849

Query: 114  NSTPLHWATRQGHLSMVVQLMKYGADPSLIDGEGCSCIHLAAQFGHTSIVAYLIAKGQDV 173
            N TPLH A  +G + + + L++  ADP++ + +G + + LA      S  A L  + +  
Sbjct: 848  NYTPLHEAAIKGKIDVCIVLLQQCADPNIRNTDGKTALDLA----DASAKAVLTGEYKKD 681

Query: 174  DMMD--QNGMTPLMWAAYRTHSVDPTRLLLTFNVSVNLGDKYHKNTALHWAVLAGNTTVI 231
            ++++  ++G    M A           LL   NV+ +  D   K+T LH A     T ++
Sbjct: 680  ELLEAARSGNEEQMMA-----------LLTPLNVNCHASDGR-KSTPLHLAAGYNRTRIV 537

Query: 232  SLLLEAGGNVDAQNVKG 248
             LLL+ G +V A++  G
Sbjct: 536  QLLLQHGADVHAKDKGG 486

 Score = 50.4 bits (119), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 48/189 (25%), Positives = 69/189 (36%)
 Frame = -1

Query: 115  STPLHWATRQGHLSMVVQLMKYGADPSLIDGEGCSCIHLAAQFGHTSIVAYLIAKGQDVD 174
            STPLH+A   G   +V  L++ GA+    D  G   +H A  FGH  +V  L+  G D +
Sbjct: 1043 STPLHFAAGFGRKDVVEHLLENGANVHARDDGGLIPLHNACSFGHAEVVQLLLRHGADPN 864

Query: 175  MMDQNGMTPLMWAAYRTHSVDPTRLLLTFNVSVNLGDKYHKNTALHWAVLAGNTTVISLL 234
              D    TP                                   LH A + G   V  +L
Sbjct: 863  ARDNWNYTP-----------------------------------LHEAAIKGKIDVCIVL 789

Query: 235  LEAGGNVDAQNVKGESALDLAKQRKNVWMINHLQEARQAKGYDKPSFLRKLKADKEFRQK 294
            L+   + + +N  G++ALDLA       +            Y K   L   ++  E  Q 
Sbjct: 788  LQQCADPNIRNTDGKTALDLADASAKAVLTGE---------YKKDELLEAARSGNE-EQM 639

Query: 295  VMLGTPFLV 303
            + L TP  V
Sbjct: 638  MALLTPLNV 612

 Score = 47.4 bits (111), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 32/95 (33%), Positives = 45/95 (47%)
 Frame = -1

Query: 115 STPLHWATRQGHLSMVVQLMKYGADPSLIDGEGCSCIHLAAQFGHTSIVAYLIAKGQDVD 174
           STPLH A       +V  L+++GAD    D  G   +H A  +GH  +   L+  G  V+
Sbjct: 584 STPLHLAAGYNRTRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHFEVTEMLLXAGASVN 405

Query: 175 MMDQNGMTPLMWAAYRTHSVDPTRLLLTFNVSVNL 209
            +D    TPL  AA ++  V+   LLL      NL
Sbjct: 404 AVDLWQFTPLHEAASKS-RVEVCSLLLAHGADPNL 303

 Score = 47.0 bits (110), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 51/192 (26%), Positives = 85/192 (44%), Gaps = 7/192 (3%)
 Frame = -1

Query: 60  YERCR---ELVEAGYDVRQPDKENVTLLHWAAINNRIDLVKYYISKGAIVDQLGGDL-NS 115
           Y R R    L++ G DV   DK  +  LH A      ++ +  +  GA V+ +  DL   
Sbjct: 557 YNRTRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHFEVTEMLLXAGASVNAV--DLWQF 384

Query: 116 TPLHWATRQGHLSMVVQLMKYGADPSLIDGEGCSCIHLAAQFGHTSIVAYLIAKGQDVDM 175
           TPLH A  +  + +   L+ +GADP+L++    S I +A              + Q+   
Sbjct: 383 TPLHEAASKSRVEVCSLLLAHGADPNLVNCHSKSIIDVAP-----------TRELQERIQ 237

Query: 176 MDQNGMTPLMWAAYRTHSVDPTRLLLTFNVSVNLGDKYHKNTALHWAVLA---GNTTVIS 232
            +  G + L  A  R   +   +  L  ++ VN    Y+ +TALH A  +       V+ 
Sbjct: 236 FEYKGHSLLEGA--RQADLARVKKYLAVDI-VNFKHPYNGDTALHCAAASPFPKRKQVVE 66

Query: 233 LLLEAGGNVDAQ 244
           LL+  GGN++ +
Sbjct: 65  LLVRKGGNLNEK 30

 Score = 28.9 bits (63), Expect = 7.1,   Method: Compositional matrix adjust.
 Identities = 15/34 (44%), Positives = 20/34 (58%)
 Frame = -1

Query: 215  KNTALHWAVLAGNTTVISLLLEAGGNVDAQNVKG 248
            K+T LH+A   G   V+  LLE G NV A++  G
Sbjct: 1046 KSTPLHFAAGFGRKDVVEHLLENGANVHARDDGG 945
>20792
          Length = 441

 Score = 50.1 bits (118), Expect = 3e-06,   Method: Composition-based stats.
 Identities = 27/80 (33%), Positives = 47/80 (58%)
 Frame = +2

Query: 84  LHWAAINNRIDLVKYYISKGAIVDQLGGDLNSTPLHWATRQGHLSMVVQLMKYGADPSLI 143
           LH  A   ++D + + + +G  VD L    + TPL  A  +  L ++  L+K+GADP+L+
Sbjct: 89  LHETAQFGQLDCMNFLLQRGVQVDCLK-RADWTPLMLACTKCQLPVISLLLKHGADPALV 265

Query: 144 DGEGCSCIHLAAQFGHTSIV 163
           + +G +  H+AA+ GH  I+
Sbjct: 266 NKDGWNSFHIAAREGHVDIL 325

 Score = 33.9 bits (76), Expect = 0.22,   Method: Composition-based stats.
 Identities = 16/45 (35%), Positives = 24/45 (53%)
 Frame = +2

Query: 146 EGCSCIHLAAQFGHTSIVAYLIAKGQDVDMMDQNGMTPLMWAAYR 190
           EG   +H  AQFG    + +L+ +G  VD + +   TPLM A  +
Sbjct: 74  EGKKPLHETAQFGQLDCMNFLLQRGVQVDCLKRADWTPLMLACTK 208
>02114
          Length = 1072

 Score = 48.5 bits (114), Expect = 7e-06,   Method: Compositional matrix adjust.
 Identities = 57/231 (24%), Positives = 95/231 (41%), Gaps = 39/231 (16%)
 Frame = +1

Query: 66  LVEAGYDVRQPDKENVTLLHWAAINNRIDLVKYYISKGAIVDQLGGDLNS-TPLHWATRQ 124
           L   G  +   D    T LH A  +     V+  +  G  V+ +  D  S T +H ++  
Sbjct: 259 LSNNGVSMSAKDTRGSTPLHLACAHGHSFCVQTLLRCGVDVNSV--DKTSWTSVHVSSYH 432

Query: 125 GHLSMVVQLMKYGADPSLIDGEGCSCIHLAAQFGHTSIVAYLIAK----GQDVDMMDQNG 180
           G L  +  L+K+GA    ID  G +  HLAA  GH   + +L++        +   + +G
Sbjct: 433 GRLGCLQMLIKWGARYDDIDTNGNTPAHLAAMEGHLPCLKFLVSSEGCPEHTLGARNDHG 612

Query: 181 MTP------------LMWAAYRTHSVD----------PTRL-----------LLTFNVSV 207
            TP            L +  +  H +D          P  +           +L  N  V
Sbjct: 613 ETPRDLAQQFYKENILEYIDHVQHEMDHPEQAENLAFPAHMAAYNGELDHLRILVENGVV 792

Query: 208 NLGDKYHK-NTALHWAVLAGNTTVISLLLEAGGNVDAQNVKGESALDLAKQ 257
           N+ ++  K NT  H A   G+  ++  L+E G +V+  N  GE+A D+A++
Sbjct: 793 NINERDDKGNTLAHRAAGQGHLNILQWLVEMGADVEISNGAGETARDIARR 945

 Score = 46.2 bits (108), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 36/121 (29%), Positives = 53/121 (43%), Gaps = 1/121 (0%)
 Frame = +1

Query: 73  VRQ-PDKENVTLLHWAAINNRIDLVKYYISKGAIVDQLGGDLNSTPLHWATRQGHLSMVV 131
           +RQ P     T  H AAI  +   ++  +S   +         STPLH A   GH   V 
Sbjct: 178 MRQ*PTPRGWTPAHIAAIRGQEGCIQA-LSNNGVSMSAKDTRGSTPLHLACAHGHSFCVQ 354

Query: 132 QLMKYGADPSLIDGEGCSCIHLAAQFGHTSIVAYLIAKGQDVDMMDQNGMTPLMWAAYRT 191
            L++ G D + +D    + +H+++  G    +  LI  G   D +D NG TP   AA   
Sbjct: 355 TLLRCGVDVNSVDKTSWTSVHVSSYHGRLGCLQMLIKWGARYDDIDTNGNTPAHLAAMEG 534

Query: 192 H 192
           H
Sbjct: 535 H 537

 Score = 45.4 bits (106), Expect = 7e-05,   Method: Compositional matrix adjust.
 Identities = 28/98 (28%), Positives = 51/98 (52%), Gaps = 2/98 (2%)
 Frame = +1

Query: 71  YDVRQPDK-ENVTL-LHWAAINNRIDLVKYYISKGAIVDQLGGDLNSTPLHWATRQGHLS 128
           +++  P++ EN+    H AA N  +D ++  +  G +      D  +T  H A  QGHL+
Sbjct: 682 HEMDHPEQAENLAFPAHMAAYNGELDHLRILVENGVVNINERDDKGNTLAHRAAGQGHLN 861

Query: 129 MVVQLMKYGADPSLIDGEGCSCIHLAAQFGHTSIVAYL 166
           ++  L++ GAD  + +G G +   +A +F H + V  L
Sbjct: 862 ILQWLVEMGADVEISNGAGETARDIARRFAHLACVKLL 975

 Score = 35.8 bits (81), Expect(2) = 9e-04,   Method: Compositional matrix adjust.
 Identities = 42/156 (26%), Positives = 60/156 (38%), Gaps = 39/156 (25%)
 Frame = +1

Query: 152 HLAAQFGHTSIVAYLIAKGQDVDMMDQNGMTPLMWAAYRTHSVDPTRLLLTFNVSVNLGD 211
           H+AA  G    +  L   G  +   D  G TPL  A    HS    + LL   V VN  D
Sbjct: 217 HIAAIRGQEGCIQALSNNGVSMSAKDTRGSTPLHLACAHGHSF-CVQTLLRCGVDVNSVD 393

Query: 212 K----------YH----------------------KNTALHWAVLAGNTTVISLLLEAGG 239
           K          YH                       NT  H A + G+   +  L+ + G
Sbjct: 394 KTSWTSVHVSSYHGRLGCLQMLIKWGARYDDIDTNGNTPAHLAAMEGHLPCLKFLVSSEG 573

Query: 240 ----NVDAQNVKGESALDLAKQ--RKNVWM-INHLQ 268
                + A+N  GE+  DLA+Q  ++N+   I+H+Q
Sbjct: 574 CPEHTLGARNDHGETPRDLAQQFYKENILEYIDHVQ 681

 Score = 25.0 bits (53), Expect(2) = 9e-04,   Method: Compositional matrix adjust.
 Identities = 18/70 (25%), Positives = 35/70 (50%), Gaps = 1/70 (1%)
 Frame = +3

Query: 84  LHWAAINNRIDLVKYYISKGAIVDQLGGDLNSTPLHWATRQGHLSMVVQLMKYGADPSLI 143
           +H A  ++ +  ++  +  GA ++++    N TP+H A   G L  +  L+ +GAD ++ 
Sbjct: 12  IHDAVRHSDVLYLEVMVKNGASINEVEDRDNFTPVHTACNIGALECLHWLLWHGADATVT 191

Query: 144 DGEGCS-CIH 152
              G   C H
Sbjct: 192 HTXGLDPCPH 221
>02055
          Length = 1740

 Score = 48.1 bits (113), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 52/208 (25%), Positives = 88/208 (42%), Gaps = 2/208 (0%)
 Frame = +3

Query: 50  DIVKATQYGIYERCRELVEAGYDVRQPDKENVTLLHWAAINNRIDLVKYYISKGAIVDQL 109
           D+ +A Q        +L+  G DV   +    T LH A ++   + +   +  GA V+  
Sbjct: 333 DLCEAVQRVCAREVDDLIRCGADVDFCNMFGDTPLHIATVHANHEAMGALVRNGANVNAR 512

Query: 110 GGDLNSTPLHWATRQGHLSMVVQLMKYGADPSLIDGEGCSCIHLAAQFGHTSIVAYLI-A 168
              LNSTPLH A R      V  L++ GA   + D  G + + +A +    ++V  L+ +
Sbjct: 513 AKFLNSTPLHVACRLRGQQEVALLIQLGARIDVNDATGTTPLQMACKRADPAVVNILLRS 692

Query: 169 KGQDVDMMDQNGMTPLMWAAYRTHSVDPTRLLLTFNVSVNLGDKYHKNTALHWAVLAGNT 228
           +   V   D N +        + H V   ++L    V+VN    Y   T +H A+     
Sbjct: 693 QPSIVRTEDANKLFKYAIQKRQLHIV---KMLCEAGVAVN----YEGTTPVHIAMDNQAW 851

Query: 229 TVISLLLEAGG-NVDAQNVKGESALDLA 255
            +    + +   N D ++ KG + L LA
Sbjct: 852 DIAKFFITSNKHNFDGRDSKGRTPLCLA 935
>34789
          Length = 1249

 Score = 47.8 bits (112), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 40/172 (23%), Positives = 76/172 (44%)
 Frame = +3

Query: 73  VRQPDKENVTLLHWAAINNRIDLVKYYISKGAIVDQLGGDLNSTPLHWATRQGHLSMVVQ 132
           + Q   +  T L  A  +  ++LV Y +  GA  +      +   LH A     + ++ +
Sbjct: 57  LNQMGSDGSTALFMAVYDGNVELVDYLLKNGA--NPHFSSQHGNFLHAAVLSQSVPLIQR 230

Query: 133 LMKYGADPSLIDGEGCSCIHLAAQFGHTSIVAYLIAKGQDVDMMDQNGMTPLMWAAYRTH 192
            +  G D +  +  G S + L ++         L+  G D++  D+   TPL+ + Y   
Sbjct: 231 ALDLGCDINEHNMFGNSPLTLVSRLDLPEACRMLVEHGADLNSRDRYRETPLLASVYFGC 410

Query: 193 SVDPTRLLLTFNVSVNLGDKYHKNTALHWAVLAGNTTVISLLLEAGGNVDAQ 244
            ++  RLL+    S++L D  H  +A++W++       + LLL AG +   Q
Sbjct: 411 ELN-ARLLIQHGASLDLVDDNH-TSAIYWSIFNNRQRTLMLLLLAGASFTPQ 560
>21532
          Length = 460

 Score = 47.4 bits (111), Expect = 2e-05,   Method: Composition-based stats.
 Identities = 37/149 (24%), Positives = 66/149 (44%)
 Frame = -1

Query: 126 HLSMVVQLMKYGADPSLIDGEGCSCIHLAAQFGHTSIVAYLIAKGQDVDMMDQNGMTPLM 185
           ++ ++  L+ +GAD ++ D  GC+    A   G+ + V  L+  G+              
Sbjct: 460 NVPIINTLLSHGADVNIRDNTGCTPFANACCLGNLAAVKALLTPGE-------------- 323

Query: 186 WAAYRTHSVDPTRLLLTFNVSVNLGDKYHKNTALHWAVLAGNTTVISLLLEAGGNVDAQN 245
                     P+      NV  N      +NT LH A   G+T ++ LL+E   ++ A+N
Sbjct: 322 ---------SPSWSKPMINVRDN-----SQNTPLHLASQEGHTAIVELLVEHKADLAAKN 185

Query: 246 VKGESALDLAKQRKNVWMINHLQEARQAK 274
             G + L LA+Q K+  ++  LQ+A   +
Sbjct: 184 DSGHNPLSLARQYKHENVVAVLQQAENTE 98

 Score = 41.6 bits (96), Expect = 0.001,   Method: Composition-based stats.
 Identities = 31/107 (28%), Positives = 50/107 (46%), Gaps = 7/107 (6%)
 Frame = -1

Query: 93  IDLVKYYISKGAIVDQLGGDLNSTPLHWATRQGHLSMVVQLMKYGADPS-------LIDG 145
           + ++   +S GA V+ +  +   TP   A   G+L+ V  L+  G  PS       + D 
Sbjct: 457 VPIINTLLSHGADVN-IRDNTGCTPFANACCLGNLAAVKALLTPGESPSWSKPMINVRDN 281

Query: 146 EGCSCIHLAAQFGHTSIVAYLIAKGQDVDMMDQNGMTPLMWAAYRTH 192
              + +HLA+Q GHT+IV  L+    D+   + +G  PL  A    H
Sbjct: 280 SQNTPLHLASQEGHTAIVELLVEHKADLAAKNDSGHNPLSLARQYKH 140

 Score = 41.2 bits (95), Expect = 0.001,   Method: Composition-based stats.
 Identities = 19/52 (36%), Positives = 35/52 (67%)
 Frame = -1

Query: 115 STPLHWATRQGHLSMVVQLMKYGADPSLIDGEGCSCIHLAAQFGHTSIVAYL 166
           +TPLH A+++GH ++V  L+++ AD +  +  G + + LA Q+ H ++VA L
Sbjct: 274 NTPLHLASQEGHTAIVELLVEHKADLAAKNDSGHNPLSLARQYKHENVVAVL 119
>30978
          Length = 566

 Score = 47.0 bits (110), Expect = 2e-05,   Method: Composition-based stats.
 Identities = 36/108 (33%), Positives = 54/108 (50%), Gaps = 5/108 (4%)
 Frame = -2

Query: 173 VDMMDQNGMTPLMWAAYRTHSVDPTRLLLT-----FNVSVNLGDKYHKNTALHWAVLAGN 227
           V+ +D+ G TPL WA +  H +D  ++LL+      NV   LGD     TALH A    +
Sbjct: 493 VNGLDKAGSTPLHWAGHGGH-MDCLQVLLSEPKCEVNVQNKLGD-----TALHSAAWKNH 332

Query: 228 TTVISLLLEAGGNVDAQNVKGESALDLAKQRKNVWMINHLQEARQAKG 275
              + +LL  G  VD +N + + A++L K  +   M+      RQA G
Sbjct: 331 VEAVKMLLGKGARVDLRNNEKKLAVELTKDPEVAAML------RQAAG 206

 Score = 38.5 bits (88), Expect = 0.008,   Method: Composition-based stats.
 Identities = 22/62 (35%), Positives = 33/62 (53%), Gaps = 1/62 (1%)
 Frame = -2

Query: 115 STPLHWATRQGHLS-MVVQLMKYGADPSLIDGEGCSCIHLAAQFGHTSIVAYLIAKGQDV 173
           STPLHWA   GH+  + V L +   + ++ +  G + +H AA   H   V  L+ KG  V
Sbjct: 469 STPLHWAGHGGHMDCLQVLLSEPKCEVNVQNKLGDTALHSAAWKNHVEAVKMLLGKGARV 290

Query: 174 DM 175
           D+
Sbjct: 289 DL 284
>20036
          Length = 1849

 Score = 47.0 bits (110), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 38/134 (28%), Positives = 62/134 (46%), Gaps = 13/134 (9%)
 Frame = +3

Query: 72   DVRQPDKENVTLLHWAAI-----NNRIDLVKYYISKGAIVDQLGGDLNS-------TPLH 119
            DV++P+K   T    A++     ++  D+++           L GD+N+       T L 
Sbjct: 963  DVKRPNKAGYTPTMLASLAFIQNDDHRDIIRQLF--------LAGDINACAEQTGQTALM 1118

Query: 120  WATRQGHLSMVVQLMKYGADPSLIDGEGCSCIHLAAQFGHTSIVAYLIAKGQ-DVDMMDQ 178
             AT Q    MV  L++ GAD +  D +G + +  A + GHT+IV  L+A+   D  + D 
Sbjct: 1119 LATSQCRTDMVELLLETGADCNQQDFDGSTALMCACEHGHTAIVQLLLAQPHCDATLTDN 1298

Query: 179  NGMTPLMWAAYRTH 192
               T L  A   +H
Sbjct: 1299 ENSTALSIAMEASH 1340

 Score = 38.5 bits (88), Expect = 0.009,   Method: Compositional matrix adjust.
 Identities = 34/116 (29%), Positives = 51/116 (43%), Gaps = 4/116 (3%)
 Frame = +3

Query: 141 SLIDGEGCSCIHLAAQFGHTSIVAYLI-AKGQDVDMMDQNGMTPLMWAAYRTHSVDPTRL 199
           +L+D  G S IH      +  IV  L+  +  DV   ++ G TP M A+      D  R 
Sbjct: 867 NLVDSNGNSAIHYCVSHCNFDIVGLLLDTEVCDVKRPNKAGYTPTMLASLAFIQNDDHRD 1046

Query: 200 L---LTFNVSVNLGDKYHKNTALHWAVLAGNTTVISLLLEAGGNVDAQNVKGESAL 252
           +   L     +N   +    TAL  A     T ++ LLLE G + + Q+  G +AL
Sbjct: 1047IIRQLFLAGDINACAEQTGQTALMLATSQCRTDMVELLLETGADCNQQDFDGSTAL 1214
>33144
          Length = 272

 Score = 45.1 bits (105), Expect = 8e-05,   Method: Composition-based stats.
 Identities = 35/115 (30%), Positives = 48/115 (41%)
 Frame = +3

Query: 145 GEGCSCIHLAAQFGHTSIVAYLIAKGQDVDMMDQNGMTPLMWAAYRTHSVDPTRLLLTFN 204
            E  + +HLAA  G T+I   L+ KG+                                 
Sbjct: 6   AENWAPLHLAAMNGRTAIAGVLVKKGE--------------------------------- 86

Query: 205 VSVNLGDKYHKNTALHWAVLAGNTTVISLLLEAGGNVDAQNVKGESALDLAKQRK 259
           V+VN+ DK HK T LH+AV     T+I LLL    N + Q+V G +   LA+  K
Sbjct: 87  VAVNVVDK-HKRTPLHYAVQTCELTIIDLLLGRDANPNIQDVDGNTPTHLAQMAK 248

 Score = 44.7 bits (104), Expect = 1e-04,   Method: Composition-based stats.
 Identities = 24/76 (31%), Positives = 40/76 (52%)
 Frame = +3

Query: 79  ENVTLLHWAAINNRIDLVKYYISKGAIVDQLGGDLNSTPLHWATRQGHLSMVVQLMKYGA 138
           EN   LH AA+N R  +    + KG +   +      TPLH+A +   L+++  L+   A
Sbjct: 9   ENWAPLHLAAMNGRTAIAGVLVKKGEVAVNVVDKHKRTPLHYAVQTCELTIIDLLLGRDA 188

Query: 139 DPSLIDGEGCSCIHLA 154
           +P++ D +G +  HLA
Sbjct: 189 NPNIQDVDGNTPTHLA 236
>25470
          Length = 400

 Score = 44.7 bits (104), Expect = 1e-04,   Method: Composition-based stats.
 Identities = 35/118 (29%), Positives = 56/118 (47%)
 Frame = -3

Query: 87  AAINNRIDLVKYYISKGAIVDQLGGDLNSTPLHWATRQGHLSMVVQLMKYGADPSLIDGE 146
           AA   R D+V++ +  GA V     D    PLH A   GH  +V  L+++GADP+  D  
Sbjct: 377 AAGFGRKDVVEHLLENGANV-HARDDGGLIPLHNACSFGHAEVVQLLLRHGADPNARDNW 201

Query: 147 GCSCIHLAAQFGHTSIVAYLIAKGQDVDMMDQNGMTPLMWAAYRTHSVDPTRLLLTFN 204
             + +H AA  G   +   L+ +  D ++ + +G T L  A     +V   +  L F+
Sbjct: 200 NYTPLHEAAIKGKIDVCIVLLQQCADPNIRNTDGKTALDLADASAKAVLTGKHALKFD 27

 Score = 38.5 bits (88), Expect = 0.007,   Method: Composition-based stats.
 Identities = 29/102 (28%), Positives = 50/102 (49%), Gaps = 1/102 (0%)
 Frame = -3

Query: 54  ATQYGIYERCRELVEAGYDVRQPDKENVTLLHWAAINNRIDLVKYYISKGAIVDQLGGD- 112
           A  +G  +    L+E G +V   D   +  LH A      ++V+  +  GA  D    D 
Sbjct: 377 AAGFGRKDVVEHLLENGANVHARDDGGLIPLHNACSFGHAEVVQLLLRHGA--DPNARDN 204

Query: 113 LNSTPLHWATRQGHLSMVVQLMKYGADPSLIDGEGCSCIHLA 154
            N TPLH A  +G + + + L++  ADP++ + +G + + LA
Sbjct: 203 WNYTPLHEAAIKGKIDVCIVLLQQCADPNIRNTDGKTALDLA 78
>03590
          Length = 1068

 Score = 44.3 bits (103), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 41/124 (33%), Positives = 54/124 (43%), Gaps = 15/124 (12%)
 Frame = +1

Query: 75  QPDKENVTL-----LHWAAINNRIDLVKYYISKGAIVDQL-GGDLNS---TPLHWATRQG 125
           +PD E  TL     L  AA +   D VK     GA VD L    LN    TP  W   Q 
Sbjct: 406 KPDLECQTLNSDTPLVLAARSQSADKVKLLAEMGANVDALIKSKLNGNHVTPCLWMAMQK 585

Query: 126 HLSMVVQLMKYGADPSLIDGEG------CSCIHLAAQFGHTSIVAYLIAKGQDVDMMDQN 179
           +L +V  L+KYGADP  +          C     +A+     ++  L+ KG  V+  D+ 
Sbjct: 586 NLPLVKLLLKYGADPKAVSAYTKETLMHCLVRDRSAEGDVIQLLKLLVEKGLSVNSRDKR 765

Query: 180 GMTP 183
           G TP
Sbjct: 766 G-TP 774
>17277
          Length = 490

 Score = 43.1 bits (100), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 20/40 (50%), Positives = 29/40 (72%)
 Frame = -1

Query: 436 KPVRSKHCGVCNRCIAKFDHHCPWVGNCVGAGNHRYFMGY 475
           +P R+ HC +C RCI + DHHCPW+ NCVG  N ++F+ +
Sbjct: 487 RPPRAHHCRICRRCIRRMDHHCPWINNCVGEYNQKFFIQF 368
>12417
          Length = 954

 Score = 42.4 bits (98), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 27/73 (36%), Positives = 36/73 (49%)
 Frame = +2

Query: 115 STPLHWATRQGHLSMVVQLMKYGADPSLIDGEGCSCIHLAAQFGHTSIVAYLIAKGQDVD 174
           S  L  A  +G   M  QL++ GAD +     G + +H A+  GH  IV  L+ KG D+D
Sbjct: 236 SVALAMAANRGLDKMCSQLIQTGADVNSATEHGRTPLHXASAQGHGHIVDLLLEKGADID 415

Query: 175 MMDQNGMTPLMWA 187
             D  G T L  A
Sbjct: 416 AEDDYGDTALSIA 454

 Score = 42.4 bits (98), Expect = 6e-04,   Method: Compositional matrix adjust.
 Identities = 25/60 (41%), Positives = 33/60 (55%), Gaps = 6/60 (10%)
 Frame = +2

Query: 108 QLGGDLNS------TPLHWATRQGHLSMVVQLMKYGADPSLIDGEGCSCIHLAAQFGHTS 161
           Q G D+NS      TPLH A+ QGH  +V  L++ GAD    D  G + + +A QFG  S
Sbjct: 296 QTGADVNSATEHGRTPLHXASAQGHGHIVDLLLEKGADIDAEDDYGDTALSIADQFGFKS 475

 Score = 40.4 bits (93), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 18/44 (40%), Positives = 28/44 (63%)
 Frame = +2

Query: 214 HKNTALHWAVLAGNTTVISLLLEAGGNVDAQNVKGESALDLAKQ 257
           H  T LH A   G+  ++ LLLE G ++DA++  G++AL +A Q
Sbjct: 329 HGRTPLHXASAQGHGHIVDLLLEKGADIDAEDDYGDTALSIADQ 460
>08473
          Length = 942

 Score = 42.0 bits (97), Expect = 8e-04,   Method: Compositional matrix adjust.
 Identities = 29/81 (35%), Positives = 41/81 (50%)
 Frame = -1

Query: 82  TLLHWAAINNRIDLVKYYISKGAIVDQLGGDLNSTPLHWATRQGHLSMVVQLMKYGADPS 141
           T L +AA    I + K  + KGA V+     L  TPL  A R+G+   V  L+K GA+P+
Sbjct: 813 TPLFYAAHRGEISICKLLVDKGANVNAADKML-ITPLMVAAREGNREAVEFLLKRGANPN 637

Query: 142 LIDGEGCSCIHLAAQFGHTSI 162
             D EG   ++ A   GH  +
Sbjct: 636 TADREGHLALYYAMAAGHPEL 574
>16561
          Length = 2029

 Score = 41.2 bits (95), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 59/225 (26%), Positives = 97/225 (43%), Gaps = 35/225 (15%)
 Frame = -3

Query: 72   DVRQPDKENVTLLHWAAINNRIDLVKYYISKGAIVDQLGGDLNSTPLHWATRQGHLSMVV 131
            D+R  D    T LH++A  N+ D+++  +SKGA ++ L     ST LH A  + H+  V 
Sbjct: 2024 DIRDGD----TALHYSAFGNQPDVLQLLLSKGAKINALNNGGCST-LHVAVNKQHIKCVH 1860

Query: 132  QLMKYGADPSLIDGEGCSCIHLA------AQFGHTSIVAYLIAKGQDVDMMDQNGMTP-- 183
             L+  G D +  D  G + +H A            SI   LI+  +       + M P  
Sbjct: 1859 VLLNXGCDVNXQDAYGDTALHDAIGKRAVKSLTSLSITLALISPSETSVASMSSIMQP*R 1680

Query: 184  ---LMWAAYRTHSVD--------------------PTRL----LLTFNVSVNLGDKYHKN 216
               L  +A  T +VD                     TR+    LL     V++ +   + 
Sbjct: 1679 AMCLPRSASCT-NVDRLWT*GKMMGFLHFTWLL*MDTRMLQQHLLRNRAEVDIRNNRQQ- 1506

Query: 217  TALHWAVLAGNTTVISLLLEAGGNVDAQNVKGESALDLAKQRKNV 261
            T L  AV  G++++I LL+ A  +++  +  G++ L LA  R+ V
Sbjct: 1505 TPLLLAVSQGHSSLIELLVHAQADINVSDEDGDTCLHLALMRQTV 1371

 Score = 32.3 bits (72), Expect = 0.56,   Method: Compositional matrix adjust.
 Identities = 17/55 (30%), Positives = 29/55 (52%)
 Frame = -3

Query: 210  GDKYHKNTALHWAVLAGNTTVISLLLEAGGNVDAQNVKGESALDLAKQRKNVWMI 264
            GD    +TALH++       V+ LLL  G  ++A N  G S L +A  ++++  +
Sbjct: 2027 GDIRDGDTALHYSAFGNQPDVLQLLLSKGAKINALNNGGCSTLHVAVNKQHIKCV 1863
>15772
          Length = 1282

 Score = 40.0 bits (92), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 34/131 (25%), Positives = 54/131 (41%), Gaps = 3/131 (2%)
 Frame = -3

Query: 54   ATQYGIYERCRELVEAG-YDV--RQPDKENVTLLHWAAINNRIDLVKYYISKGAIVDQLG 110
            A   G Y+   + V++G YDV  + PD  N T LHWA     ++ ++  +  GA      
Sbjct: 1265 AASTGDYDALEDYVKSGIYDVNLKDPDAGNKTALHWACQKGFVECIRLLLDHGA-KGTAR 1089

Query: 111  GDLNSTPLHWATRQGHLSMVVQLMKYGADPSLIDGEGCSCIHLAAQFGHTSIVAYLIAKG 170
             D   TP H A     ++ +  L        L D  G +   +A  +GH     YL+   
Sbjct: 1088 TDTGWTPAHCAAECNRVTALRALHAALVPVDLTDKYGDTPRRIATLYGHRDCARYLLQAE 909

Query: 171  QDVDMMDQNGM 181
             +V    + G+
Sbjct: 908  AEVAERRRKGL 876

 Score = 28.5 bits (62), Expect = 9.2,   Method: Compositional matrix adjust.
 Identities = 19/44 (43%), Positives = 21/44 (47%), Gaps = 1/44 (2%)
 Frame = -3

Query: 206  SVNLGDKYHKN-TALHWAVLAGNTTVISLLLEAGGNVDAQNVKG 248
             VNL D    N TALHWA   G    I LLL+ G    A+   G
Sbjct: 1208 DVNLKDPDAGNKTALHWACQKGFVECIRLLLDHGAKGTARTDTG 1077
>09214
          Length = 2116

 Score = 39.7 bits (91), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 27/86 (31%), Positives = 41/86 (47%), Gaps = 4/86 (4%)
 Frame = -3

Query: 116  TPLHWATRQGHLSMVVQLMKYGADPSLIDGEGCSCIHLAAQFGHTSIVAYLIAKGQDVDM 175
            T LHW  ++ H ++V  L+ +GAD + +D +G     +A Q    S V  L+    DV  
Sbjct: 1604 TALHWGAKRDHQTVVQYLLSHGADKNAVDNDG----KIAGQLTTNSDVHTLLGGSGDVTN 1437

Query: 176  MDQNGMTPLMWA----AYRTHSVDPT 197
             +Q  +TP   A     Y T S  P+
Sbjct: 1436 QEQLPITPSYLAHPPFPYSTKSELPS 1359

 Score = 34.3 bits (77), Expect = 0.15,   Method: Compositional matrix adjust.
 Identities = 19/54 (35%), Positives = 29/54 (53%)
 Frame = -3

Query: 198  RLLLTFNVSVNLGDKYHKNTALHWAVLAGNTTVISLLLEAGGNVDAQNVKGESA 251
            +L+   NV VN  +K +  TALHW     + TV+  LL  G + +A +  G+ A
Sbjct: 1661 KLVEVKNVDVNAQNKMNGRTALHWGAKRDHQTVVQYLLSHGADKNAVDNDGKIA 1500
>28691
          Length = 562

 Score = 38.1 bits (87), Expect = 0.010,   Method: Composition-based stats.
 Identities = 31/84 (36%), Positives = 42/84 (50%), Gaps = 4/84 (4%)
 Frame = +1

Query: 178 QNGMTPLMWAAYRTHSVDPTRLLLTFNVSVNLG--DKYHKNTALHWAVLAGNTTVISL-- 233
           ++G+  L  AA   H VD   +L+     VN         NTALH AV  G + V S+  
Sbjct: 112 KSGLPALHLAAKNKH-VDCIPVLVQAGADVNAKGPSTIKGNTALHEAVSVGASNVDSVDA 288

Query: 234 LLEAGGNVDAQNVKGESALDLAKQ 257
           LL  G + +  N KGE+A DLA +
Sbjct: 289 LLSCGADQNIXNEKGETAYDLASK 360
>38834
          Length = 496

 Score = 38.1 bits (87), Expect = 0.010,   Method: Composition-based stats.
 Identities = 19/73 (26%), Positives = 36/73 (49%)
 Frame = -1

Query: 121 ATRQGHLSMVVQLMKYGADPSLIDGEGCSCIHLAAQFGHTSIVAYLIAKGQDVDMMDQNG 180
           A   GHL +   L + G   ++++  G +  HL+  F    I  +L+    +++ ++  G
Sbjct: 493 ACSSGHLDIAEMLHRRGVQINVVNINGYTPXHLSVYFNKFDITHFLVKINAEINTVNNAG 314

Query: 181 MTPLMWAAYRTHS 193
            TP+  AA R +S
Sbjct: 313 QTPVYLAALRGNS 275
>28494
          Length = 463

 Score = 38.1 bits (87), Expect = 0.011,   Method: Composition-based stats.
 Identities = 20/64 (31%), Positives = 34/64 (53%)
 Frame = -1

Query: 121 ATRQGHLSMVVQLMKYGADPSLIDGEGCSCIHLAAQFGHTSIVAYLIAKGQDVDMMDQNG 180
           A   G    V +L++ GAD +  + +G + +H A    +  +V +L+ +  DVD+ D  G
Sbjct: 298 ACSSGDRDEVKKLLERGADINTANVDGLTALHQACIDDNLDMVEFLVEQNADVDVCDNEG 119

Query: 181 MTPL 184
            TPL
Sbjct: 118 WTPL 107
>08755
          Length = 885

 Score = 36.6 bits (83), Expect = 0.031,   Method: Compositional matrix adjust.
 Identities = 23/74 (31%), Positives = 37/74 (50%), Gaps = 1/74 (1%)
 Frame = +3

Query: 112 DLNSTPLHWATRQGHLSMVVQLMKYGADPSL-IDGEGCSCIHLAAQFGHTSIVAYLIAKG 170
           D   + LH A +   +  V  L+ +GA+P + +DG G + + LAA    T+ +  LI  G
Sbjct: 648 DDGQSALHIAVKNPEVISV--LLAHGANPDVKVDGSGVTPLMLAASMTKTAALQILIGAG 821

Query: 171 QDVDMMDQNGMTPL 184
             +D  +  GM  L
Sbjct: 822 SSIDCRNNAGMCAL 863
>28113
          Length = 449

 Score = 35.8 bits (81), Expect = 0.055,   Method: Composition-based stats.
 Identities = 18/64 (28%), Positives = 38/64 (59%), Gaps = 1/64 (1%)
 Frame = -3

Query: 118 LHWATRQGHLSMVVQLMKYGADPSLIDGEGCSCIHLAAQFGHTSIVAYLI-AKGQDVDMM 176
           +H+A+  G   +V  L+  G  P+L + E  + +H+AA+ G   +  +L+ A+  D+++ 
Sbjct: 222 IHYASWYGSADVVEILLDAGCSPNLTNSELLTPLHIAAKKGFPDVAEHLVQAEAIDLNLR 43

Query: 177 DQNG 180
           D++G
Sbjct: 42  DKDG 31
>21751
          Length = 643

 Score = 35.8 bits (81), Expect = 0.055,   Method: Compositional matrix adjust.
 Identities = 25/82 (30%), Positives = 40/82 (48%), Gaps = 8/82 (9%)
 Frame = +3

Query: 66  LVEAGYDVRQ------PDK--ENVTLLHWAAINNRIDLVKYYISKGAIVDQLGGDLNSTP 117
           L++ G DV Q       DK   + + LH A +   + L +  +  G  V+Q   D   +P
Sbjct: 12  LIQYGADVHQLRTVSLDDKVFTSQSPLHVAILRKNVHLGRLLLEHGEDVNQTFNDSLESP 191

Query: 118 LHWATRQGHLSMVVQLMKYGAD 139
           +H A R   L M+  L+++GAD
Sbjct: 192 IHQAVRNLDLDMINLLIEFGAD 257
>20884
          Length = 712

 Score = 35.4 bits (80), Expect = 0.077,   Method: Compositional matrix adjust.
 Identities = 19/51 (37%), Positives = 31/51 (60%), Gaps = 1/51 (1%)
 Frame = +2

Query: 139 DPSLIDGEGCSCIHLAAQFGHTSIVAYLIAKGQDVDMMD-QNGMTPLMWAA 188
           D ++ + EG +C HLA Q GH  I+  L+ +G +++  D ++G T L  AA
Sbjct: 527 DLAIRNYEGYTCAHLALQTGHLHILPLLLERGANINEQDGKSGRTLLHMAA 679

 Score = 34.3 bits (77), Expect = 0.15,   Method: Compositional matrix adjust.
 Identities = 28/97 (28%), Positives = 45/97 (46%), Gaps = 2/97 (2%)
 Frame = +1

Query: 77  DKENVTLLHWAAINNRIDLVKYYISKGAIVD--QLGGDLNSTPLHWATRQGHLSMVVQLM 134
           D++  + LH + I+   D+    IS     D   +   L+ TPLH A     + +V +LM
Sbjct: 181 DEDGDSYLHMSIIHLLPDVSLKVISVAPSPDYINIPNMLHQTPLHLAVATRQMWVVRRLM 360

Query: 135 KYGADPSLIDGEGCSCIHLAAQFGHTSIVAYLIAKGQ 171
             GA     D  G + +H+A + G T +V  L+   Q
Sbjct: 361 VAGAAMEAPDYCGNTALHIACREGMTEMVKLLLTPVQ 471

 Score = 29.6 bits (65), Expect = 4.1,   Method: Compositional matrix adjust.
 Identities = 16/49 (32%), Positives = 29/49 (59%), Gaps = 1/49 (2%)
 Frame = +2

Query: 119 HWATRQGHLSMVVQLMKYGADPSLIDGE-GCSCIHLAAQFGHTSIVAYL 166
           H A + GHL ++  L++ GA+ +  DG+ G + +H+AA  G+   +  L
Sbjct: 566 HLALQTGHLHILPLLLERGANINEQDGKSGRTLLHMAADLGYLQALELL 712
>13900
          Length = 751

 Score = 35.0 bits (79), Expect = 0.093,   Method: Compositional matrix adjust.
 Identities = 17/51 (33%), Positives = 27/51 (52%)
 Frame = +1

Query: 116 TPLHWATRQGHLSMVVQLMKYGADPSLIDGEGCSCIHLAAQFGHTSIVAYL 166
           +PLH A R        +L+K G+DP L D  G + + +A    + +IV Y+
Sbjct: 286 SPLHLAVRVNDFHKAKKLLKLGSDPLLPDFSGITPLRMAQGHEYNAIVFYM 438

 Score = 33.5 bits (75), Expect = 0.27,   Method: Compositional matrix adjust.
 Identities = 40/162 (24%), Positives = 63/162 (38%), Gaps = 3/162 (1%)
 Frame = +1

Query: 146 EGCSCIHLAAQFGHTSIVAYLIAKGQDVDMMDQNGMTPLMWAAYRTHSVDPTRLLLTFNV 205
            G S +HLA +         L+  G D  + D +G+TPL  A  + H  +     + +  
Sbjct: 277 SGQSPLHLAVRVNDFHKAKKLLKLGSDPLLPDFSGITPLRMA--QGHEYNAIVFYMCYVR 450

Query: 206 SVNLGDKYHKNTALHWAVLAGNTTVISLLLEAGGNVD---AQNVKGESALDLAKQRKNVW 262
            +N+       T L  AV       I +LL +G N D        G++ L+LA       
Sbjct: 451 DINVNVMVRGETTLQQAVRDNYLLGIQVLLRSGANPDLVVRMPSYGQNCLELA------V 612

Query: 263 MINHLQEARQAKGYDKPSFLRKLKADKEFRQKVMLGTPFLVI 304
           M  ++   R    ++   FL  L +          GTP+ VI
Sbjct: 613 MCRYVNAVRALIVHNCKPFLHSLLSPVTTGHGRGSGTPWRVI 738
>30463
          Length = 412

 Score = 34.7 bits (78), Expect = 0.10,   Method: Composition-based stats.
 Identities = 26/85 (30%), Positives = 37/85 (43%)
 Frame = -1

Query: 82  TLLHWAAINNRIDLVKYYISKGAIVDQLGGDLNSTPLHWATRQGHLSMVVQLMKYGADPS 141
           T  H AA+N   + V      GA +D    D   TPLH A+  GH+  V  L+   A  +
Sbjct: 382 TATHLAAMNGHSNAVMVLNIMGASIDCRTVD-KQTPLHLASSAGHIECVKCLVANKASLT 206

Query: 142 LIDGEGCSCIHLAAQFGHTSIVAYL 166
             D    +   LA Q+G   +  +L
Sbjct: 205 AEDAFSRTAYDLADQYGQNDVADFL 131

 Score = 30.8 bits (68), Expect = 1.7,   Method: Composition-based stats.
 Identities = 25/88 (28%), Positives = 38/88 (43%)
 Frame = -1

Query: 147 GCSCIHLAAQFGHTSIVAYLIAKGQDVDMMDQNGMTPLMWAAYRTHSVDPTRLLLTFNVS 206
           G +  HLAA  GH++ V  L   G  +D    +  TPL  A+   H ++  + L+    S
Sbjct: 388 GYTATHLAAMNGHSNAVMVLNIMGASIDCRTVDKQTPLHLASSAGH-IECVKCLVANKAS 212

Query: 207 VNLGDKYHKNTALHWAVLAGNTTVISLL 234
           +   D + + TA   A   G   V   L
Sbjct: 211 LTAEDAFSR-TAYDLADQYGQNDVADFL 131
>22269
          Length = 1060

 Score = 34.3 bits (77), Expect = 0.16,   Method: Compositional matrix adjust.
 Identities = 20/58 (34%), Positives = 29/58 (50%)
 Frame = +1

Query: 133 LMKYGADPSLIDGEGCSCIHLAAQFGHTSIVAYLIAKGQDVDMMDQNGMTPLMWAAYR 190
           L+KYGA+P+ +D    +  HLAA  G    +  L+ KG        N +T +M  A R
Sbjct: 28  LLKYGANPNAVDRYNVTAAHLAAHSGSAQCLKTLLIKGAKA-----NCLTMVMPEAVR 186
>27108
          Length = 449

 Score = 34.3 bits (77), Expect = 0.17,   Method: Composition-based stats.
 Identities = 33/110 (30%), Positives = 48/110 (43%), Gaps = 21/110 (19%)
 Frame = -3

Query: 166 LIAKGQDVDMMDQNGMTPLMWAAYRTHSVDPTRLLLTFNVSVNLGDKYH--KN------- 216
           L   G D++  D  G T L  A    H ++  R LL F  S  L   +   KN       
Sbjct: 327 LTVPGVDINSQDYAGWTALHEACNHGH-LECARALLKFVPSATLDSFFQSGKNRGKVRKV 151

Query: 217 ----------TALHWAVLAGNTTVISLLLEAGGN--VDAQNVKGESALDL 254
                     TALH AV   + +V+ LLL+ GG+  +  + V G++ +DL
Sbjct: 150 DMHLANQEGITALHDAVSMNHVSVVKLLLKYGGSSLLKDKTVSGDTVMDL 1
>11861
          Length = 586

 Score = 33.9 bits (76), Expect = 0.20,   Method: Compositional matrix adjust.
 Identities = 15/43 (34%), Positives = 24/43 (55%)
 Frame = -1

Query: 148 CSCIHLAAQFGHTSIVAYLIAKGQDVDMMDQNGMTPLMWAAYR 190
           C  +H AA+     IV + +  G D++ +D+ G TPL   AY+
Sbjct: 484 CIALHEAAKRHQWDIVDHCLTHGADINKVDEQGFTPLFRVAYK 356
>25464
          Length = 440

 Score = 32.7 bits (73), Expect = 0.43,   Method: Compositional matrix adjust.
 Identities = 26/85 (30%), Positives = 39/85 (45%), Gaps = 4/85 (4%)
 Frame = -3

Query: 66  LVEAGYDVRQPDKENVTLLHWAAINNRIDLVKYYIS---KGAIVDQLGGDLNSTPLHWAT 122
           L E   D+ +PD +  T +H AAI+   ++V+       K  +       L  TPL  A 
Sbjct: 351 LKEDVLDINEPDNDGNTPIHHAAISANPNIVRMLAEAFYKFGLNPDKRNKLGYTPLLLAC 172

Query: 123 RQG-HLSMVVQLMKYGADPSLIDGE 146
           + G ++S    L    A P+L DGE
Sbjct: 171 KGGNYVSAYTLLTTTKASPTLRDGE 97
>04513
          Length = 434

 Score = 32.3 bits (72), Expect = 0.65,   Method: Composition-based stats.
 Identities = 16/48 (33%), Positives = 25/48 (52%)
 Frame = -2

Query: 154 AAQFGHTSIVAYLIAKGQDVDMMDQNGMTPLMWAAYRTHSVDPTRLLL 201
           A+++G    V  L+ KG  V+ + +  +TPLMWA      V    LL+
Sbjct: 433 ASKYGDKDTVQVLLDKGGQVNAVGKYKLTPLMWACCSRDDVAVVNLLI 290
>30217
          Length = 412

 Score = 32.0 bits (71), Expect = 0.86,   Method: Composition-based stats.
 Identities = 20/72 (27%), Positives = 36/72 (50%), Gaps = 2/72 (2%)
 Frame = -3

Query: 75  QPDKENVTLLHWAAINNRIDLVKYYI--SKGAIVDQLGGDLNSTPLHWATRQGHLSMVVQ 132
           Q + +  T LH A I+  +D+V   I  +    +  +  D+  TPLH A      +++  
Sbjct: 221 QQNDDGDTPLHLACISGYVDVVAALIRMAPHPCLLNIQNDVAQTPLHLAALTAQPTILRM 42

Query: 133 LMKYGADPSLID 144
           L+  GA+P++ D
Sbjct: 41  LLLAGAEPTVRD 6
>15359
          Length = 780

 Score = 31.6 bits (70), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 25/90 (27%), Positives = 39/90 (43%), Gaps = 2/90 (2%)
 Frame = +1

Query: 116 TPLHWATRQGHLSMVVQLM-KYGADPSLIDGEGCSCIHLAAQFGHTSIVAYLIAK-GQDV 173
           T LHWA + G   +V  L  K G + +     G + +HLAA  GH  I+  L+     D 
Sbjct: 355 TALHWAAKFGKPEVVKMLANKIGVEINQRSHGGYTPLHLAAIHGHEDIIELLVTGYKADA 534

Query: 174 DMMDQNGMTPLMWAAYRTHSVDPTRLLLTF 203
           ++ D +G     +      S    +  L+F
Sbjct: 535 NIRDYSGKKAKQYLKNSASSRAQRKPFLSF 624
>28491
          Length = 394

 Score = 30.4 bits (67), Expect = 2.2,   Method: Composition-based stats.
 Identities = 15/40 (37%), Positives = 21/40 (52%)
 Frame = +3

Query: 162 IVAYLIAKGQDVDMMDQNGMTPLMWAAYRTHSVDPTRLLL 201
           ++  L+ +G DV+  D  GMT LM       SVD  R L+
Sbjct: 255 LIKLLLRQGSDVNAQDDAGMTSLMHVIAEGGSVDAVRPLI 374
>09370
          Length = 274

 Score = 30.0 bits (66), Expect = 3.0,   Method: Composition-based stats.
 Identities = 17/46 (36%), Positives = 25/46 (54%)
 Frame = +1

Query: 565 FKVTTTSIESPFNHGCVRNIIDFFEFRCCGLFRPVIVDWTRQYTIE 610
           FKV T+S  S  N  C    ID       G+F P++++W R+ T+E
Sbjct: 7   FKVITSSFSS*RNLFC---FIDVHSSIQVGVFNPLVINW*RKPTLE 135
>21550
          Length = 415

 Score = 29.3 bits (64), Expect = 4.5,   Method: Composition-based stats.
 Identities = 11/35 (31%), Positives = 13/35 (37%)
 Frame = +3

Query: 429 CSTCLIRKPVRSKHCGVCNRCIAKFDHHCPWVGNC 463
           C  C  +      HC  C RC+     HC   G C
Sbjct: 48  CDACTSKDGTTYVHCEACXRCVKATRVHCQTCGVC 152
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|51230692|ref|NP_001003719.1| GTPase activating RANGAP
domain-like 1 isoform 3 [Mus musculus]
         (2083 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

25758                                                                  79   2e-14
31328                                                                  52   2e-06
12703                                                                  31   6.6  
>25758
          Length = 425

 Score = 78.6 bits (192), Expect = 2e-14,   Method: Compositional matrix adjust.
 Identities = 52/120 (43%), Positives = 72/120 (60%), Gaps = 3/120 (2%)
 Frame = -1

Query: 971  NQQAFSAEVATVTGSESASPVHSALG-SRSQTPSPSTL-SRAHIEQKDLQLDEKLHHSVL 1028
            N++ F A   + T S ++  +HSA   S S++PSP+ L S +  +       + LH  ++
Sbjct: 359  NEEYFHAARESCTPSPTS--MHSARSKSGSRSPSPTELISDSQPKDSPTPDRDSLHIDMV 186

Query: 1029 QTPDDLEIS-EFPSECCSVMAGGTLTGWHADVATVMWRRMLGILGDVNAIMDPEIHAQVF 1087
             +  D  +S +   E  SVMAGGTL GW  DVA V+W+RMLG LGDVN I DP+IHA VF
Sbjct: 185  ASNQDTSLSRDSLLENKSVMAGGTLPGWTPDVAVVLWQRMLGCLGDVNKIEDPDIHASVF 6
>31328
          Length = 418

 Score = 52.0 bits (123), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 28/77 (36%), Positives = 49/77 (63%), Gaps = 1/77 (1%)
 Frame = +3

Query: 1874 TVEVIFHVSTRMPS-DSDDSLTKKLRHLGNDEVHIVWSEHTRDYRRGIIPTEFGDVLIVI 1932
            +++VIFH++T M +   D +LT K RH+GND V IV+++   +Y+ G +  +F  V IVI
Sbjct: 93   SMKVIFHIATLMRNRKQDHNLTFKKRHVGNDFVTIVYNDSGEEYKLGTLMGQFNFVNIVI 272

Query: 1933 YPMKNHMFSIQIMKKPE 1949
             P+ +   ++ ++ K E
Sbjct: 273  RPLDHGGNAVTLLAKQE 323
>12703
          Length = 1529

 Score = 30.8 bits (68), Expect = 6.6,   Method: Composition-based stats.
 Identities = 20/65 (30%), Positives = 30/65 (46%)
 Frame = -1

Query: 1134 TMLTDKYKQGKLHAYKLICNTMKRRQDVSPNRDFLTHFYNIMHCGLLHIDQDIVNTIIKH 1193
            TML    + G L       NT++ R   SPN D  T FY+I+  G+  ++ +        
Sbjct: 1433 TMLKSLDRDGSLPTPNDDTNTLQYRVKCSPNNDADTLFYHILKIGISDVNDN-------- 1278

Query: 1194 CSPQF 1198
             +PQF
Sbjct: 1277 -APQF 1266
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|9910548|ref|NP_064373.1| SH3-binding domain glutamic
acid-rich protein like [Mus musculus]
         (114 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

32026                                                                  74   2e-14
18626                                                                  42   5e-05
15991                                                                  28   1.0  
34603                                                                  26   4.9  
02259                                                                  25   9.5  
>32026
          Length = 431

 Score = 73.6 bits (179), Expect = 2e-14,   Method: Compositional matrix adjust.
 Identities = 40/101 (39%), Positives = 60/101 (59%), Gaps = 2/101 (1%)
 Frame = +1

Query: 2   VIRVYIASSSGSTAIKKKQQDVLCFLEANKIGFEEKDIA--ANEENRKWMRENVPEDSRP 59
           +I+V++ S  G+  ++K+QQ VL  LE  +I F+  D+   + EE+RK+MR N    +  
Sbjct: 127 LIKVFVTSVPGNVNLRKQQQQVLDILEGLRIPFQTVDVCDPSREEDRKFMRTN--SKALK 300

Query: 60  STGYPLPPQIFNECQYRGDYDAFFEARENNAVYAFLGLTAP 100
               PLPPQIFN+  Y G +D+F  + E N +Y FL L  P
Sbjct: 301 PGAVPLPPQIFNQDNYCGGFDSFEFSVETNQLYEFLKLENP 423
>18626
          Length = 401

 Score = 42.4 bits (98), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 21/50 (42%), Positives = 29/50 (58%)
 Frame = +3

Query: 60  STGYPLPPQIFNECQYRGDYDAFFEARENNAVYAFLGLTAPPGSKEAEAQ 109
           S G P PPQ+FN+ +Y GDY+AF  A E + +  FL L     +  + AQ
Sbjct: 69  SQGIPWPPQLFNDDEYCGDYNAFDNANEIDTLEVFLKLAPADTTAISSAQ 218
>15991
          Length = 1629

 Score = 28.1 bits (61), Expect = 1.0,   Method: Composition-based stats.
 Identities = 8/24 (33%), Positives = 15/24 (62%)
 Frame = +3

Query: 53  VPEDSRPSTGYPLPPQIFNECQYR 76
           +P  +RP+   P+PP ++  C+ R
Sbjct: 870 IPVSTRPTGTVPIPPILYTSCRGR 941
>34603
          Length = 772

 Score = 25.8 bits (55), Expect = 4.9,   Method: Compositional matrix adjust.
 Identities = 12/39 (30%), Positives = 20/39 (51%)
 Frame = +2

Query: 45  NRKWMRENVPEDSRPSTGYPLPPQIFNECQYRGDYDAFF 83
           +R W+R  +    RP+ GYP+P  ++ +   R  Y   F
Sbjct: 656 SRVWVRLQM----RPTQGYPMPSPLWADVGTRDTYSLGF 760
>02259
          Length = 1921

 Score = 24.6 bits (52), Expect = 9.5,   Method: Compositional matrix adjust.
 Identities = 12/34 (35%), Positives = 14/34 (41%)
 Frame = +2

Query: 60 STGYPLPPQIFNECQYRGDYDAFFEARENNAVYA 93
          STG P PP +F      G         +NNA  A
Sbjct: 62 STGLPQPPSVFGAGAGTGQTFGLAPGSQNNAAAA 163
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31541957|ref|NP_080402.2| FUN14 domain containing 2
[Mus musculus]
         (151 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

11215                                                                  74   3e-14
00218                                                                  29   0.88 
>11215
          Length = 680

 Score = 73.9 bits (180), Expect = 3e-14,   Method: Compositional matrix adjust.
 Identities = 45/137 (32%), Positives = 77/137 (56%)
 Frame = +1

Query: 1   MAANSQGNFDGKFEALDLAELTKKQPWWRKLFGQESGPSAEKYSVATQLVIGGVTGWCTG 60
           MAANS      ++E LDL+ + +   W R++  +  G    + S   Q+ +G V+G   G
Sbjct: 115 MAANSDSEVSEEYEVLDLSNINEN--WLRQMTKRTLG-DISRQSAIKQVGVGSVSGVVAG 285

Query: 61  FVFQKVGKLAATDVGGGFFLLQLANHTGYIKVDWQRVEKDMKKAKEQLKIRKNKQIPTEV 120
           ++F KVGK+AA  +G    L+Q+A H GYI+++W RV   ++KA+E++    N+  P   
Sbjct: 286 WLFVKVGKVAAATLGTTILLIQVAQHQGYIQINWDRVRSTVRKAEEEVTRSANRHYP--- 456

Query: 121 KSKAEEVVSFVKKNVLV 137
              A  +  FV++N+ +
Sbjct: 457 -GVARNLRDFVRQNLFL 504
>00218
          Length = 1300

 Score = 28.9 bits (63), Expect = 0.88,   Method: Compositional matrix adjust.
 Identities = 14/37 (37%), Positives = 18/37 (48%)
 Frame = -3

Query: 28  WRKLFGQESGPSAEKYSVATQLVIGGVTGWCTGFVFQ 64
           W  LFG E      KYSV++ ++  G    C  FVF 
Sbjct: 737 WVSLFGGEDPSCFSKYSVSSCMISDGYCKPCLLFVFP 627
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|63548702|ref|XP_132817.5| PREDICTED: ankyrin repeat
domain 26 isoform 1 [Mus musculus]
         (1681 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

06253                                                                  78   3e-14
05924                                                                  72   3e-12
08473                                                                  70   6e-12
14005                                                                  63   8e-10
25470                                                                  62   2e-09
09292                                                                  62   3e-09
00540                                                                  59   1e-08
19166                                                                  53   1e-06
16561                                                                  52   2e-06
11295                                                                  51   3e-06
13462                                                                  51   4e-06
02114                                                                  49   1e-05
21532                                                                  48   3e-05
12417                                                                  47   5e-05
34789                                                                  47   7e-05
28494                                                                  44   4e-04
15359                                                                  44   6e-04
33144                                                                  41   0.004
20036                                                                  41   0.005
25464                                                                  39   0.018
30978                                                                  39   0.020
05396                                                                  38   0.030
20792                                                                  37   0.048
15772                                                                  37   0.054
27108                                                                  37   0.057
09180                                                                  37   0.063
27067                                                                  37   0.084
02055                                                                  36   0.16 
22305                                                                  35   0.20 
28113                                                                  35   0.21 
35952                                                                  34   0.51 
02351                                                                  34   0.57 
20121                                                                  33   0.99 
30463                                                                  32   1.7  
22269                                                                  32   2.1  
13358                                                                  31   4.9  
09214                                                                  30   6.7  
28743                                                                  30   7.6  
>06253
          Length = 1049

 Score = 77.8 bits (190), Expect = 3e-14,   Method: Composition-based stats.
 Identities = 59/184 (32%), Positives = 86/184 (46%), Gaps = 21/184 (11%)
 Frame = -1

Query: 51   IHKAASVGDVAKVQHILILGKSGVNDRDKKDRTALHLACAYGHPEVVTLLVERKCEIDAR 110
            +H AA  G    V+H+L  G + V+ RD      LH AC++GH EVV LL+    + +AR
Sbjct: 1034 LHFAAGFGRKDVVEHLLENG-ANVHARDDGGLIPLHNACSFGHAEVVQLLLRHGADPNAR 858

Query: 111  DSESSTALIKAVQCQEEECAAILLDHGADPNVMDSSGNTALHYAVYSENT---------- 160
            D+ + T L +A    + +   +LL   ADPN+ ++ G TAL  A  S             
Sbjct: 857  DNWNYTPLHEAAIKGKIDVCIVLLQQCADPNIRNTDGKTALDLADASAKAVLTGEYKKDE 678

Query: 161  -----------SMAAKLLAHNANIEAKNKDDLTPMLLAVKENKQHIVEFLVKKKASIHAV 209
                        M A L   N N  A +    TP+ LA   N+  IV+ L++  A +HA 
Sbjct: 677  LLEAARSGNEEQMMALLTPLNVNCHASDGRKSTPLHLAAGYNRTRIVQLLLQHGADVHAK 498

Query: 210  DQLG 213
            D+ G
Sbjct: 497  DKGG 486

 Score = 55.8 bits (133), Expect = 2e-07,   Method: Composition-based stats.
 Identities = 36/108 (33%), Positives = 47/108 (43%)
 Frame = -1

Query: 80   KDRTALHLACAYGHPEVVTLLVERKCEIDARDSESSTALIKAVQCQEEECAAILLDHGAD 139
            +  T LH A  +G  +VV  L+E    + ARD      L  A      E   +LL HGAD
Sbjct: 1049 RKSTPLHFAAGFGRKDVVEHLLENGANVHARDDGGLIPLHNACSFGHAEVVQLLLRHGAD 870

Query: 140  PNVMDSSGNTALHYAVYSENTSMAAKLLAHNANIEAKNKDDLTPMLLA 187
            PN  D+   T LH A       +   LL   A+   +N D  T + LA
Sbjct: 869  PNARDNWNYTPLHEAAIKGKIDVCIVLLQQCADPNIRNTDGKTALDLA 726

 Score = 53.5 bits (127), Expect = 7e-07,   Method: Composition-based stats.
 Identities = 36/108 (33%), Positives = 54/108 (50%)
 Frame = -1

Query: 51  IHKAASVGDVAKVQHILILGKSGVNDRDKKDRTALHLACAYGHPEVVTLLVERKCEIDAR 110
           +H AA       VQ +L  G + V+ +DK     LH AC+YGH EV  +L+     ++A 
Sbjct: 575 LHLAAGYNRTRIVQLLLQHG-ADVHAKDKGGLVPLHNACSYGHFEVTEMLLXAGASVNAV 399

Query: 111 DSESSTALIKAVQCQEEECAAILLDHGADPNVMDSSGNTALHYAVYSE 158
           D    T L +A      E  ++LL HGADPN+++    + +  A   E
Sbjct: 398 DLWQFTPLHEAASKSRVEVCSLLLAHGADPNLVNCHSKSIIDVAPTRE 255
>05924
          Length = 704

 Score = 71.6 bits (174), Expect = 3e-12,   Method: Composition-based stats.
 Identities = 48/165 (29%), Positives = 81/165 (49%)
 Frame = +1

Query: 47  DMGKIHKAASVGDVAKVQHILILGKSGVNDRDKKDRTALHLACAYGHPEVVTLLVERKCE 106
           D   +H+A S+     VQ +LI   +  N  ++  RTALHLAC  G+  +V +L+    +
Sbjct: 64  DSTLLHEAVSMASEDLVQ-MLIKAGANANSTNQDGRTALHLACRGGYTNIVQILIAAGTD 240

Query: 107 IDARDSESSTALIKAVQCQEEECAAILLDHGADPNVMDSSGNTALHYAVYSENTSMAAKL 166
           ++ R  +  T L  AV     E    L++ GAD N+ DS G + L++A  S  T++   L
Sbjct: 241 VNRRTVDGKTCLHVAVWRGHTEVVVKLVNAGADVNIPDSVGCSPLYWAARSNYTAILTVL 420

Query: 167 LAHNANIEAKNKDDLTPMLLAVKENKQHIVEFLVKKKASIHAVDQ 211
           +   A +  + K   TP+  A+      +V +L+ + A  +   Q
Sbjct: 421 VNAGAKVNYRVKSKWTPLHAALHLGHMGVVRYLLLQGAETNITVQ 555

 Score = 52.4 bits (124), Expect = 1e-06,   Method: Composition-based stats.
 Identities = 44/158 (27%), Positives = 65/158 (41%), Gaps = 5/158 (3%)
 Frame = +1

Query: 55  ASVGDVAKVQHILILGKSGVNDRDKKDRTALHLACAYGHPEVVTLLVERKCEIDARDSES 114
           A  G    +  ILI   + VN R    +T LH+A   GH EVV  LV    +++  DS  
Sbjct: 184 ACRGGYTNIVQILIAAGTDVNRRTVDGKTCLHVAVWRGHTEVVVKLVNAGADVNIPDSVG 363

Query: 115 STALIKAVQCQEEECAAILLDHGADPNVMDSSGNTALHYAVYSENTSMAAKLLAHNANIE 174
            + L  A +        +L++ GA  N    S  T LH A++  +  +   LL   A   
Sbjct: 364 CSPLYWAARSNYTAILTVLVNAGAKVNYRVKSKWTPLHAALHLGHMGVVRYLLLQGAETN 543

Query: 175 AKNKDDLTPMLLAVKENKQH-----IVEFLVKKKASIH 207
              +D     LL   E+  H      +  LVK   ++H
Sbjct: 544 ITVQDKTVVSLLMDNEHLSHKERERTLAMLVKAGYNLH 657
>08473
          Length = 942

 Score = 70.5 bits (171), Expect = 6e-12,   Method: Compositional matrix adjust.
 Identities = 38/108 (35%), Positives = 58/108 (53%)
 Frame = -1

Query: 106 EIDARDSESSTALIKAVQCQEEECAAILLDHGADPNVMDSSGNTALHYAVYSENTSMAAK 165
           ++D RDS   TAL  A       C   LL  GA+P  M+  G T L YA +    S+   
Sbjct: 942 DVDMRDSNDMTALHHACAGLHYGCVHALLQGGANPTCMEMGGKTPLFYAAHRGEISICKL 763

Query: 166 LLAHNANIEAKNKDDLTPMLLAVKENKQHIVEFLVKKKASIHAVDQLG 213
           L+   AN+ A +K  +TP+++A +E  +  VEFL+K+ A+ +  D+ G
Sbjct: 762 LVDKGANVNAADKMLITPLMVAAREGNREAVEFLLKRGANPNTADREG 619

 Score = 47.8 bits (112), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 33/109 (30%), Positives = 50/109 (45%)
 Frame = -1

Query: 47  DMGKIHKAASVGDVAKVQHILILGKSGVNDRDKKDRTALHLACAYGHPEVVTLLVERKCE 106
           DM  +H A + G      H L+ G +     +   +T L  A   G   +  LLV++   
Sbjct: 918 DMTALHHACA-GLHYGCVHALLQGGANPTCMEMGGKTPLFYAAHRGEISICKLLVDKGAN 742

Query: 107 IDARDSESSTALIKAVQCQEEECAAILLDHGADPNVMDSSGNTALHYAV 155
           ++A D    T L+ A +    E    LL  GA+PN  D  G+ AL+YA+
Sbjct: 741 VNAADKMLITPLMVAAREGNREAVEFLLKRGANPNTADREGHLALYYAM 595
>14005
          Length = 1745

 Score = 63.2 bits (152), Expect = 8e-10,   Method: Composition-based stats.
 Identities = 52/198 (26%), Positives = 88/198 (44%), Gaps = 36/198 (18%)
 Frame = -1

Query: 54   AASVGDVAKVQHILILGKSGVNDRDKKDRTALHLAC-------------------AY--- 91
            A+ +G +A V  +L +    VN+RD+K R AL+ AC                   AY   
Sbjct: 1724 ASRMGHLAVVSELLKVPGIDVNERDEKLRPALYFACMGNDIELVKQLVRYGARVNAYSTE 1545

Query: 92   ------------GHPEVVTLLVERKCEIDARDSESSTALIKAVQCQEEECAAILLDHGAD 139
                        G P +   L+      ++R  +  T L+ A +  + E A +L+  GA+
Sbjct: 1544 TWWTPFHACCKRGDPRIALYLLRHGANKESRTVDGKTPLVVACKNDKAEVALLLIRSGAN 1365

Query: 140  PNV-MDSSGNTALHYAVYSENTSMAAKLLAHNANIEAKNKDDLTPMLLA-VKENKQHIVE 197
             NV  D + NT +H+A    N  +  +L+ H A+++  N    T + +A V+  KQH++ 
Sbjct: 1364 VNVSCDITANTPVHFACQRPNIELLKRLVLHGADVDKPNAKGHTALHVASVRGFKQHVIY 1185

Query: 198  FLVKKKASIHAVDQLGSN 215
             L    A ++A    G+N
Sbjct: 1184 LLDFCDAEVNAATLKGNN 1131

 Score = 37.4 bits (85), Expect = 0.051,   Method: Composition-based stats.
 Identities = 41/151 (27%), Positives = 64/151 (42%), Gaps = 4/151 (2%)
 Frame = -1

Query: 67   LILGKSGVN--DRDKKDRTALHLACAYGHPEVVTLLVERKCEIDAR-DSESSTALIKAVQ 123
            L L + G N   R    +T L +AC     EV  LL+     ++   D  ++T +  A Q
Sbjct: 1490 LYLLRHGANKESRTVDGKTPLVVACKNDKAEVALLLIRSGANVNVSCDITANTPVHFACQ 1311

Query: 124  CQEEECAAILLDHGADPNVMDSSGNTALHYAVYSENTSMAAKLLAH-NANIEAKNKDDLT 182
                E    L+ HGAD +  ++ G+TALH A           LL   +A + A       
Sbjct: 1310 RPNIELLKRLVLHGADVDKPNAKGHTALHVASVRGFKQHVIYLLDFCDAEVNAATLKGNN 1131

Query: 183  PMLLAVKENKQHIVEFLVKKKASIHAVDQLG 213
             + +A +     +VE L+ K A+    +Q G
Sbjct: 1130 ALHIACRGKHADLVELLLHKGANPAQRNQRG 1038

 Score = 33.5 bits (75), Expect = 0.74,   Method: Composition-based stats.
 Identities = 27/86 (31%), Positives = 37/86 (43%), Gaps = 4/86 (4%)
 Frame = -1

Query: 45   DKDMGKIHKAASVGDVAKV-QHILIL---GKSGVNDRDKKDRTALHLACAYGHPEVVTLL 100
            DK   K H A  V  V    QH++ L     + VN    K   ALH+AC   H ++V LL
Sbjct: 1259 DKPNAKGHTALHVASVRGFKQHVIYLLDFCDAEVNAATLKGNNALHIACRGKHADLVELL 1080

Query: 101  VERKCEIDARDSESSTALIKAVQCQE 126
            + +      R+    T    A +C E
Sbjct: 1079 LHKGANPAQRNQRGWTPRNSAGRCXE 1002
>25470
          Length = 400

 Score = 61.6 bits (148), Expect = 2e-09,   Method: Composition-based stats.
 Identities = 40/112 (35%), Positives = 59/112 (52%)
 Frame = -3

Query: 54  AASVGDVAKVQHILILGKSGVNDRDKKDRTALHLACAYGHPEVVTLLVERKCEIDARDSE 113
           AA  G    V+H+L  G + V+ RD      LH AC++GH EVV LL+    + +ARD+ 
Sbjct: 377 AAGFGRKDVVEHLLENG-ANVHARDDGGLIPLHNACSFGHAEVVQLLLRHGADPNARDNW 201

Query: 114 SSTALIKAVQCQEEECAAILLDHGADPNVMDSSGNTALHYAVYSENTSMAAK 165
           + T L +A    + +   +LL   ADPN+ ++ G TAL  A  S    +  K
Sbjct: 200 NYTPLHEAAIKGKIDVCIVLLQQCADPNIRNTDGKTALDLADASAKAVLTGK 45

 Score = 52.0 bits (123), Expect = 2e-06,   Method: Composition-based stats.
 Identities = 34/101 (33%), Positives = 44/101 (43%)
 Frame = -3

Query: 87  LACAYGHPEVVTLLVERKCEIDARDSESSTALIKAVQCQEEECAAILLDHGADPNVMDSS 146
           LA  +G  +VV  L+E    + ARD      L  A      E   +LL HGADPN  D+ 
Sbjct: 380 LAAGFGRKDVVEHLLENGANVHARDDGGLIPLHNACSFGHAEVVQLLLRHGADPNARDNW 201

Query: 147 GNTALHYAVYSENTSMAAKLLAHNANIEAKNKDDLTPMLLA 187
             T LH A       +   LL   A+   +N D  T + LA
Sbjct: 200 NYTPLHEAAIKGKIDVCIVLLQQCADPNIRNTDGKTALDLA 78
>09292
          Length = 1486

 Score = 61.6 bits (148), Expect = 3e-09,   Method: Composition-based stats.
 Identities = 41/123 (33%), Positives = 62/123 (50%), Gaps = 2/123 (1%)
 Frame = -2

Query: 84   ALHLACAYGHPEVVTLL--VERKCEIDARDSESSTALIKAVQCQEEECAAILLDHGADPN 141
            ALH  CA    +V TLL  ++    +D RDS   TAL         + A++LL H AD N
Sbjct: 1452 ALH--CAXQLQDVETLLAYLDIGMHVDTRDSHHETALHAVCYVGSVKMASVLLKHXADVN 1279

Query: 142  VMDSSGNTALHYAVYSENTSMAAKLLAHNANIEAKNKDDLTPMLLAVKENKQHIVEFLVK 201
              ++   T LH      +  +  +L+ H A+  A++KD LTP+  A  +N   IV +L++
Sbjct: 1278 ARNNVDRTPLHIXAIEGHLGLVEELVRHGADFNAEDKDHLTPVFNACVKNDTDIVRYLLE 1099

Query: 202  KKA 204
              A
Sbjct: 1098 SGA 1090

 Score = 57.8 bits (138), Expect = 4e-08,   Method: Composition-based stats.
 Identities = 60/251 (23%), Positives = 101/251 (40%), Gaps = 22/251 (8%)
 Frame = -2

Query: 45  DKDMGK-IHKAASVGDVAKVQHILILGKSGVNDRDKKDRTALHLACAYGHPEVVTLLVER 103
           DKD    +H +      A++  +LI   + V   +   +  LHLAC Y + E   LL+  
Sbjct: 891 DKDGNTPLHISVRAPSSAQLVRLLIRFGANVKWGNDNQQIPLHLACLYSNLETARLLLHC 712

Query: 104 KCEIDARDSESSTALIKAVQCQEEECAAILLDHGADPNVMDSSGNTALHYAVYSENTSMA 163
               +   S+  T L  AV     +   ++L   +D N  D   N  LH A   +   +A
Sbjct: 711 GSCSNELSSKLWTPLHYAVIGGNVDIVRLVLQGSSDVNSPDGRNNAPLHLACMKQCIGIA 532

Query: 164 AKLLAHNANIEAKNKDDLTPMLLAVKENKQHIVEFLVKKKASIHAVDQLGSNRQMFEYDG 223
             LL H AN+     +  TP+ +A+  +   +V  L             G+N Q+ ++DG
Sbjct: 531 RCLLRHGANVNVSGYNGRTPLHIAISHHNLELVLLLY----------MCGANDQLVDFDG 382

Query: 224 K--------------RLQRSENSNPVDN----GSEDGSLTRSYN--TPGPAD-SWPTSDE 262
                          R + S N+ P +     G  D +  R+      G ++ S P+ ++
Sbjct: 381 NFPSCYSMCHIHGCLRRRTSHNATPANEPCAGGEYDSAADRNLAKVQQGASNVSLPSGND 202

Query: 263 EDYNFDNKNVP 273
            +   DN N+P
Sbjct: 201 GENKTDNSNLP 169

 Score = 56.6 bits (135), Expect = 8e-08,   Method: Composition-based stats.
 Identities = 51/202 (25%), Positives = 86/202 (42%), Gaps = 30/202 (14%)
 Frame = -2

Query: 35   GSHVPRYHIHDKDMGKIHKAASVGDVAKVQHILILGKSGVNDRDKKDRTALHLACAYGHP 94
            G HV     H +    +H    VG V K+  +L+   + VN R+  DRT LH+    GH 
Sbjct: 1392 GMHVDTRDSHHET--ALHAVCYVGSV-KMASVLLKHXADVNARNNVDRTPLHIXAIEGHL 1222

Query: 95   EVVTLLVERKCEIDARDSE-----------------------------SSTALIKAVQCQ 125
             +V  LV    + +A D +                             ++  +  AV+  
Sbjct: 1221 GLVEELVRHGADFNAEDKDHLTPVFNACVKNDTDIVRYLLESGARANTTARPIFHAVKYG 1042

Query: 126  EEECAAILLDHGADPNVMDSSGNTALHYAVYSENTSMAAKLLAHNANIEAKNKDDLTPML 185
              E   +LL HGA  N +  +  + LH A  + N  MA  ++   AN+ A +KD  TP+ 
Sbjct: 1041 YSEIVQLLLVHGAAVNSLPGT-KSPLHIACRNGNIEMARTVIIAGANVNAVDKDGNTPLH 865

Query: 186  LAVKE-NKQHIVEFLVKKKASI 206
            ++V+  +   +V  L++  A++
Sbjct: 864  ISVRAPSSAQLVRLLIRFGANV 799

 Score = 55.8 bits (133), Expect = 2e-07,   Method: Composition-based stats.
 Identities = 36/98 (36%), Positives = 49/98 (50%)
 Frame = -2

Query: 114  SSTALIKAVQCQEEECAAILLDHGADPNVMDSSGNTALHYAVYSENTSMAAKLLAHNANI 173
            S  AL  A Q Q+ E     LD G   +  DS   TALH   Y  +  MA+ LL H A++
Sbjct: 1461 SFCALHCAXQLQDVETLLAYLDIGMHVDTRDSHHETALHAVCYVGSVKMASVLLKHXADV 1282

Query: 174  EAKNKDDLTPMLLAVKENKQHIVEFLVKKKASIHAVDQ 211
             A+N  D TP+ +   E    +VE LV+  A  +A D+
Sbjct: 1281 NARNNVDRTPLHIXAIEGHLGLVEELVRHGADFNAEDK 1168
>00540
          Length = 3034

 Score = 59.3 bits (142), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 45/127 (35%), Positives = 60/127 (47%)
 Frame = -2

Query: 74   VNDRDKKDRTALHLACAYGHPEVVTLLVERKCEIDARDSESSTALIKAVQCQEEECAAIL 133
            VN   + + T L  AC  GH EVV  LVE K EI+  +S   T L+ A      +    L
Sbjct: 2991 VNQTTRSNSTPLRAACYDGHLEVVQFLVEHKAEIEIANSHGHTCLMIACYRGHLDVVEYL 2812

Query: 134  LDHGADPNVMDSSGNTALHYAVYSENTSMAAKLLAHNANIEAKNKDDLTPMLLAVKENKQ 193
            L  GA  N     GNTALH +  S   S+   LL+  A + AK+    TP+  A     +
Sbjct: 2811 LYLGAQVNRRSVKGNTALHDSAESGKLSIMKLLLSKGAKM-AKDAYGQTPLSAAAMTGHE 2635

Query: 194  HIVEFLV 200
             IV +L+
Sbjct: 2634 EIVRYLI 2614

 Score = 43.1 bits (100), Expect = 8e-04,   Method: Compositional matrix adjust.
 Identities = 35/114 (30%), Positives = 48/114 (42%), Gaps = 2/114 (1%)
 Frame = -2

Query: 71   KSGVNDRDKKDRTALHLACAYGHPEVVTLLVERKCEIDARDSESSTALIKAVQCQEEECA 130
            K+G+ D D    + LHLAC                     ++ SS   ++          
Sbjct: 1869 KTGITDPDGA--SPLHLAC--------------------MENISSFGRVRMSHFPSLSVT 1756

Query: 131  AILLDHGADPNVMDSSGNTALHYAVYSENTSMAA--KLLAHNANIEAKNKDDLT 182
             IL+  GAD N  DS GN ALH+A   +   MA    LLA  A+ +  NK+ LT
Sbjct: 1755 RILIKVGADTNARDSQGNVALHFASMGKKVRMAVVEALLAGGAHADVCNKNHLT 1594
>19166
          Length = 447

 Score = 52.8 bits (125), Expect = 1e-06,   Method: Composition-based stats.
 Identities = 41/147 (27%), Positives = 64/147 (43%)
 Frame = +1

Query: 62  KVQHILILGKSGVNDRDKKDRTALHLACAYGHPEVVTLLVERKCEIDARDSESSTALIKA 121
           K   +L+  K   N R     T LH+AC     +VV LL++    IDA      T L  +
Sbjct: 1   KTAKLLLDRKCEPNSRALNGFTPLHIACKKNRIKVVELLLKYGASIDATTESGLTPLHVS 180

Query: 122 VQCQEEECAAILLDHGADPNVMDSSGNTALHYAVYSENTSMAAKLLAHNANIEAKNKDDL 181
                      L+ H A P+     G T+LH A  +  T +   LL + A ++A+ ++  
Sbjct: 181 SFMGHMNIVIYLIQHNAYPDTPTVRGETSLHLAARANQTDIIRILLRNGAAVDARAREQQ 360

Query: 182 TPMLLAVKENKQHIVEFLVKKKASIHA 208
           TP+ +A +      V  L++  AS  A
Sbjct: 361 TPLHIASRLGNVDNVVLLLQHGASADA 441

 Score = 30.0 bits (66), Expect = 7.2,   Method: Composition-based stats.
 Identities = 17/51 (33%), Positives = 27/51 (52%)
 Frame = +1

Query: 163 AAKLLAHNANIEAKNKDDLTPMLLAVKENKQHIVEFLVKKKASIHAVDQLG 213
           A  LL       ++  +  TP+ +A K+N+  +VE L+K  ASI A  + G
Sbjct: 7   AKLLLDRKCEPNSRALNGFTPLHIACKKNRIKVVELLLKYGASIDATTESG 159
>16561
          Length = 2029

 Score = 52.4 bits (124), Expect = 2e-06,   Method: Composition-based stats.
 Identities = 27/73 (36%), Positives = 43/73 (58%)
 Frame = -3

Query: 83   TALHLACAYGHPEVVTLLVERKCEIDARDSESSTALIKAVQCQEEECAAILLDHGADPNV 142
            TALH +     P+V+ LL+ +  +I+A ++   + L  AV  Q  +C  +LL+ G D N 
Sbjct: 2006 TALHYSAFGNQPDVLQLLLSKGAKINALNNGGCSTLHVAVNKQHIKCVHVLLNXGCDVNX 1827

Query: 143  MDSSGNTALHYAV 155
             D+ G+TALH A+
Sbjct: 1826 QDAYGDTALHDAI 1788

 Score = 38.9 bits (89), Expect = 0.017,   Method: Compositional matrix adjust.
 Identities = 27/88 (30%), Positives = 46/88 (52%), Gaps = 1/88 (1%)
 Frame = -3

Query: 32   SASGSHVPRYHIHDKDMGKIHKAASV-GDVAKVQHILILGKSGVNDRDKKDRTALHLACA 90
            SAS ++V R     K MG +H    +  D   +Q  L+  ++ V+ R+ + +T L LA +
Sbjct: 1661 SASCTNVDRLWT*GKMMGFLHFTWLL*MDTRMLQQHLLRNRAEVDIRNNRQQTPLLLAVS 1482

Query: 91   YGHPEVVTLLVERKCEIDARDSESSTAL 118
             GH  ++ LLV  + +I+  D +  T L
Sbjct: 1481 QGHSSLIELLVHAQADINVSDEDGDTCL 1398

 Score = 37.7 bits (86), Expect = 0.041,   Method: Composition-based stats.
 Identities = 28/88 (31%), Positives = 43/88 (48%), Gaps = 2/88 (2%)
 Frame = -3

Query: 147  GNTALHYAVYSENTSMAAKLLAHNANIEAKNKDDLTPMLLAVKENKQHI--VEFLVKKKA 204
            G+TALHY+ +     +   LL+  A I A N    + + +AV  NKQHI  V  L+    
Sbjct: 2012 GDTALHYSAFGNQPDVLQLLLSKGAKINALNNGGCSTLHVAV--NKQHIKCVHVLLNXGC 1839

Query: 205  SIHAVDQLGSNRQMFEYDGKRLQRSENS 232
             ++  D  G +  + +  GKR  +S  S
Sbjct: 1838 DVNXQDAYG-DTALHDAIGKRAVKSLTS 1758

 Score = 34.7 bits (78), Expect = 0.33,   Method: Compositional matrix adjust.
 Identities = 17/48 (35%), Positives = 28/48 (58%)
 Frame = -3

Query: 166  LLAHNANIEAKNKDDLTPMLLAVKENKQHIVEFLVKKKASIHAVDQLG 213
            LL + A ++ +N    TP+LLAV +    ++E LV  +A I+  D+ G
Sbjct: 1553 LLRNRAEVDIRNNRQQTPLLLAVSQGHSSLIELLVHAQADINVSDEDG 1410

 Score = 30.4 bits (67), Expect = 6.5,   Method: Composition-based stats.
 Identities = 18/52 (34%), Positives = 27/52 (51%)
 Frame = -2

Query: 51   IHKAASVGDVAKVQHILILGKSGVNDRDKKDRTALHLACAYGHPEVVTLLVE 102
            +H AA  G+V   + +L   +  V+ R     +ALHLA   GH +V   L+E
Sbjct: 1701 LHHAALKGNVFATERVLHKCRQIVDLRKDDGFSALHLAALNGHKDVAAALIE 1546
>11295
          Length = 1179

 Score = 51.2 bits (121), Expect = 3e-06,   Method: Composition-based stats.
 Identities = 43/154 (27%), Positives = 66/154 (42%), Gaps = 5/154 (3%)
 Frame = +1

Query: 41  YHIHDKDMGKIHKAASVGDVAKVQHILILGKSG----VNDRDKKDRTALHLACAYGHPEV 96
           Y    + +  +H A  +G   +V  +L+ G +G    VN       TALH+AC     E+
Sbjct: 46  YWTDHRGLSALHHAC-IGRNTEVAELLLDGWNGDGIAVNATSNDHVTALHIACCLDDREM 222

Query: 97  VTLLVERKCEIDARDSESSTALIKAVQCQEEECAAILLDHG-ADPNVMDSSGNTALHYAV 155
            +LL++      A D    T L  A  C  E    +LLD    D N +D  G   L  A 
Sbjct: 223 ASLLLKYGAYAMALDVIGHTPLHVACWCGSEGVTRLLLDRSDVDVNALDHDGKXPLRLAS 402

Query: 156 YSENTSMAAKLLAHNANIEAKNKDDLTPMLLAVK 189
                 +  +LL HNA+   ++  + TP   A++
Sbjct: 403 ECGFHYIIRQLLYHNADHTIRDAAEFTPFHCAIR 504

 Score = 42.7 bits (99), Expect = 0.001,   Method: Composition-based stats.
 Identities = 37/132 (28%), Positives = 58/132 (43%), Gaps = 1/132 (0%)
 Frame = +1

Query: 77  RDKKDRTALHLACAYGHPEVV-TLLVERKCEIDARDSESSTALIKAVQCQEEECAAILLD 135
           RD  + T  H A  Y     V T LV     I +  ++ S   +  +QC ++E  ++L+ 
Sbjct: 463 RDAAEFTPFHCAIRYCRVLAVKTFLVWFPDLIHSFYNDLSPTFMACLQC-DKEMLSLLIK 639

Query: 136 HGADPNVMDSSGNTALHYAVYSENTSMAAKLLAHNANIEAKNKDDLTPMLLAVKENKQHI 195
            GA  N  D    T LHY     + +M   LL   A     + + +TP+ +A  E    I
Sbjct: 640 FGASVNCADHYHYTPLHYISRRGHLTMLQLLLQGKAEPNVVDDEGITPLYIASCEGHVTI 819

Query: 196 VEFLVKKKASIH 207
           V  L++  A I+
Sbjct: 820 VNILLQSGAKIY 855

 Score = 31.6 bits (70), Expect = 2.8,   Method: Composition-based stats.
 Identities = 32/124 (25%), Positives = 54/124 (43%), Gaps = 5/124 (4%)
 Frame = +1

Query: 95  EVVTLLVERKCEIDARDSESSTALIKAVQCQEEECAAILLD----HGADPNVMDSSGNTA 150
           + V  L++   +I   D    +AL  A   +  E A +LLD     G   N   +   TA
Sbjct: 7   QTVLTLLQGGAQIYWTDHRGLSALHHACIGRNTEVAELLLDGWNGDGIAVNATSNDHVTA 186

Query: 151 LHYAVYSENTSMAAKLLAHNANIEAKNKDDLTPMLLAVKENKQHIVEFLV-KKKASIHAV 209
           LH A   ++  MA+ LL + A   A +    TP+ +A     + +   L+ +    ++A+
Sbjct: 187 LHIACCLDDREMASLLLKYGAYAMALDVIGHTPLHVACWCGSEGVTRLLLDRSDVDVNAL 366

Query: 210 DQLG 213
           D  G
Sbjct: 367 DHDG 378
>13462
          Length = 1388

 Score = 50.8 bits (120), Expect = 4e-06,   Method: Composition-based stats.
 Identities = 25/70 (35%), Positives = 38/70 (54%)
 Frame = +3

Query: 131 AILLDHGADPNVMDSSGNTALHYAVYSENTSMAAKLLAHNANIEAKNKDDLTPMLLAVKE 190
           ++LL +GA PNV D  GNTALH A    N  +   LL    ++   + D+ TP++ A   
Sbjct: 234 SMLLAYGAQPNVQDEDGNTALHLACSESNVDVVRLLLEWGGDVAVADIDNETPLVRACLA 413

Query: 191 NKQHIVEFLV 200
           N   +V+ L+
Sbjct: 414 NSVELVDLLL 443

 Score = 50.1 bits (118), Expect = 7e-06,   Method: Composition-based stats.
 Identities = 32/93 (34%), Positives = 51/93 (54%), Gaps = 2/93 (2%)
 Frame = +3

Query: 51  IHKAA--SVGDVAKVQHILILGKSGVNDRDKKDRTALHLACAYGHPEVVTLLVERKCEID 108
           +H A+  S G++  V  +L  G    N +D+   TALHLAC+  + +VV LL+E   ++ 
Sbjct: 189 LHYASHHSNGNLGIVSMLLAYGAQP-NVQDEDGNTALHLACSESNVDVVRLLLEWGGDVA 365

Query: 109 ARDSESSTALIKAVQCQEEECAAILLDHGADPN 141
             D ++ T L++A      E   +LL  G+DPN
Sbjct: 366 VADIDNETPLVRACLANSVELVDLLLHAGSDPN 464

 Score = 41.2 bits (95), Expect = 0.004,   Method: Composition-based stats.
 Identities = 27/113 (23%), Positives = 55/113 (48%), Gaps = 2/113 (1%)
 Frame = +3

Query: 83  TALHLACAYGHPEVVTLLVERKCEIDARDSESSTALIKAVQCQE--EECAAILLDHGADP 140
           T L  A  + + +++ +L     +++       TAL  A   QE   +   +LL  G++P
Sbjct: 561 TYLSFASEHNYLDMMKVLHNYGVDVNGTGRLGLTALHHACISQEATHDAVRLLLLWGSNP 740

Query: 141 NVMDSSGNTALHYAVYSENTSMAAKLLAHNANIEAKNKDDLTPMLLAVKENKQ 193
           N++  +G+T LH+A  +   S    LL + A++   +    +P++ A+   +Q
Sbjct: 741 NLVTGTGDTPLHFACQTFAVSKVRLLLMYGADVNQIDGTHTSPLIAALTTRRQ 899
>02114
          Length = 1072

 Score = 49.3 bits (116), Expect = 1e-05,   Method: Composition-based stats.
 Identities = 43/152 (28%), Positives = 74/152 (48%), Gaps = 4/152 (2%)
 Frame = +1

Query: 52  HKAASVGDVAKVQHILILGKSGVNDRDKKDRTALHLACAYGHPEVVTLLVERKCEIDARD 111
           H AA  G    +Q +   G S ++ +D +  T LHLACA+GH   V  L+    ++++ D
Sbjct: 217 HIAAIRGQEGCIQALSNNGVS-MSAKDTRGSTPLHLACAHGHSFCVQTLLRCGVDVNSVD 393

Query: 112 SESSTALIKAVQCQEEECAAILLDHGADPNVMDSSGNTALHYAVYSENTSMAAKLLAHNA 171
             S T++  +       C  +L+  GA  + +D++GNT  H A    +      L++   
Sbjct: 394 KTSWTSVHVSSYHGRLGCLQMLIKWGARYDDIDTNGNTPAHLAAMEGHLPCLKFLVSSEG 573

Query: 172 NIE----AKNKDDLTPMLLAVKENKQHIVEFL 199
             E    A+N    TP  LA +  K++I+E++
Sbjct: 574 CPEHTLGARNDHGETPRDLAQQFYKENILEYI 669

 Score = 34.7 bits (78), Expect = 0.38,   Method: Compositional matrix adjust.
 Identities = 28/92 (30%), Positives = 43/92 (46%), Gaps = 3/92 (3%)
 Frame = +1

Query: 52  HKAASVGDVAKVQHILILGKSGV---NDRDKKDRTALHLACAYGHPEVVTLLVERKCEID 108
           H AA  G++    H+ IL ++GV   N+RD K  T  H A   GH  ++  LVE   +++
Sbjct: 730 HMAAYNGEL---DHLRILVENGVVNINERDDKGNTLAHRAAGQGHLNILQWLVEMGADVE 900

Query: 109 ARDSESSTALIKAVQCQEEECAAILLDHGADP 140
             +    TA   A +     C  +L   G +P
Sbjct: 901 ISNGAGETARDIARRFAHLACVKLL---GGEP 987
>21532
          Length = 460

 Score = 47.8 bits (112), Expect = 3e-05,   Method: Composition-based stats.
 Identities = 39/127 (30%), Positives = 57/127 (44%), Gaps = 13/127 (10%)
 Frame = -1

Query: 133 LLDHGADPNVMDSSGNTALHYAVYSENTSMAAKLLAHNAN-------IEAKNKDDLTPML 185
           LL HGAD N+ D++G T    A    N +    LL    +       I  ++    TP+ 
Sbjct: 439 LLSHGADVNIRDNTGCTPFANACCLGNLAAVKALLTPGESPSWSKPMINVRDNSQNTPLH 260

Query: 186 LAVKENKQHIVEFLVKKKASIHAVDQLGSNRQMFEYDGKR------LQRSENSNPVDNGS 239
           LA +E    IVE LV+ KA + A +  G N        K       LQ++EN+ PV   +
Sbjct: 259 LASQEGHTAIVELLVEHKADLAAKNDSGHNPLSLARQYKHENVVAVLQQAENTEPVIPTN 80

Query: 240 EDGSLTR 246
            D ++ R
Sbjct: 79  YDCTVAR 59

 Score = 47.0 bits (110), Expect = 7e-05,   Method: Composition-based stats.
 Identities = 30/86 (34%), Positives = 44/86 (51%), Gaps = 6/86 (6%)
 Frame = -1

Query: 54  AASVGDVAKVQHILILGKSG------VNDRDKKDRTALHLACAYGHPEVVTLLVERKCEI 107
           A  +G++A V+ +L  G+S       +N RD    T LHLA   GH  +V LLVE K ++
Sbjct: 376 ACCLGNLAAVKALLTPGESPSWSKPMINVRDNSQNTPLHLASQEGHTAIVELLVEHKADL 197

Query: 108 DARDSESSTALIKAVQCQEEECAAIL 133
            A++      L  A Q + E   A+L
Sbjct: 196 AAKNDSGHNPLSLARQYKHENVVAVL 119
>12417
          Length = 954

 Score = 47.4 bits (111), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 27/68 (39%), Positives = 34/68 (50%)
 Frame = +2

Query: 67  LILGKSGVNDRDKKDRTALHLACAYGHPEVVTLLVERKCEIDARDSESSTALIKAVQCQE 126
           LI   + VN   +  RT LH A A GH  +V LL+E+  +IDA D    TAL  A Q   
Sbjct: 290 LIQTGADVNSATEHGRTPLHXASAQGHGHIVDLLLEKGADIDAEDDYGDTALSIADQFGF 469

Query: 127 EECAAILL 134
           + C   L 
Sbjct: 470 KSCGRXLF 493

 Score = 32.7 bits (73), Expect = 1.4,   Method: Compositional matrix adjust.
 Identities = 16/52 (30%), Positives = 28/52 (53%)
 Frame = +2

Query: 162 MAAKLLAHNANIEAKNKDDLTPMLLAVKENKQHIVEFLVKKKASIHAVDQLG 213
           M ++L+   A++ +  +   TP+  A  +   HIV+ L++K A I A D  G
Sbjct: 278 MCSQLIQTGADVNSATEHGRTPLHXASAQGHGHIVDLLLEKGADIDAEDDYG 433
>34789
          Length = 1249

 Score = 47.0 bits (110), Expect = 7e-05,   Method: Composition-based stats.
 Identities = 32/131 (24%), Positives = 61/131 (46%)
 Frame = +3

Query: 42  HIHDKDMGKIHKAASVGDVAKVQHILILGKSGVNDRDKKDRTALHLACAYGHPEVVTLLV 101
           H   +    +H A     V  +Q  L LG   +N+ +    + L L      PE   +LV
Sbjct: 159 HFSSQHGNFLHAAVLSQSVPLIQRALDLG-CDINEHNMFGNSPLTLVSRLDLPEACRMLV 335

Query: 102 ERKCEIDARDSESSTALIKAVQCQEEECAAILLDHGADPNVMDSSGNTALHYAVYSENTS 161
           E   ++++RD    T L+ +V    E  A +L+ HGA  +++D +  +A+++++++    
Sbjct: 336 EHGADLNSRDRYRETPLLASVYFGCELNARLLIQHGASLDLVDDNHTSAIYWSIFNNRQR 515

Query: 162 MAAKLLAHNAN 172
               LL   A+
Sbjct: 516 TLMLLLLAGAS 548

 Score = 38.1 bits (87), Expect = 0.032,   Method: Composition-based stats.
 Identities = 34/149 (22%), Positives = 66/149 (44%), Gaps = 1/149 (0%)
 Frame = +3

Query: 58  GDVAKVQHILILGKSGVNDR-DKKDRTALHLACAYGHPEVVTLLVERKCEIDARDSESST 116
           G+V  V ++L   K+G N     +    LH A       ++   ++  C+I+  +   ++
Sbjct: 111 GNVELVDYLL---KNGANPHFSSQHGNFLHAAVLSQSVPLIQRALDLGCDINEHNMFGNS 281

Query: 117 ALIKAVQCQEEECAAILLDHGADPNVMDSSGNTALHYAVYSENTSMAAKLLAHNANIEAK 176
            L    +    E   +L++HGAD N  D    T L  +VY      A  L+ H A+++  
Sbjct: 282 PLTLVSRLDLPEACRMLVEHGADLNSRDRYRETPLLASVYFGCELNARLLIQHGASLDLV 461

Query: 177 NKDDLTPMLLAVKENKQHIVEFLVKKKAS 205
           + +  + +  ++  N+Q  +  L+   AS
Sbjct: 462 DDNHTSAIYWSIFNNRQRTLMLLLLAGAS 548

 Score = 33.9 bits (76), Expect = 0.54,   Method: Composition-based stats.
 Identities = 34/137 (24%), Positives = 57/137 (41%)
 Frame = +3

Query: 74  VNDRDKKDRTALHLACAYGHPEVVTLLVERKCEIDARDSESSTALIKAVQCQEEECAAIL 133
           +N       TAL +A   G+ E+V  L++         S+    L  AV  Q        
Sbjct: 57  LNQMGSDGSTALFMAVYDGNVELVDYLLKNGAN-PHFSSQHGNFLHAAVLSQSVPLIQRA 233

Query: 134 LDHGADPNVMDSSGNTALHYAVYSENTSMAAKLLAHNANIEAKNKDDLTPMLLAVKENKQ 193
           LD G D N  +  GN+ L      +       L+ H A++ ++++   TP+L +V    +
Sbjct: 234 LDLGCDINEHNMFGNSPLTLVSRLDLPEACRMLVEHGADLNSRDRYRETPLLASVYFGCE 413

Query: 194 HIVEFLVKKKASIHAVD 210
                L++  AS+  VD
Sbjct: 414 LNARLLIQHGASLDLVD 464
>28494
          Length = 463

 Score = 44.3 bits (103), Expect = 4e-04,   Method: Composition-based stats.
 Identities = 30/86 (34%), Positives = 46/86 (53%)
 Frame = -1

Query: 54  AASVGDVAKVQHILILGKSGVNDRDKKDRTALHLACAYGHPEVVTLLVERKCEIDARDSE 113
           A S GD  +V+ +L  G + +N  +    TALH AC   + ++V  LVE+  ++D  D+E
Sbjct: 298 ACSSGDRDEVKKLLERG-ADINTANVDGLTALHQACIDDNLDMVEFLVEQNADVDVCDNE 122

Query: 114 SSTALIKAVQCQEEECAAILLDHGAD 139
             T L     C   E A  LL++GA+
Sbjct: 121 GWTPLHATASCGFTEIARYLLENGAN 44

 Score = 39.7 bits (91), Expect = 0.011,   Method: Composition-based stats.
 Identities = 27/85 (31%), Positives = 42/85 (49%)
 Frame = -1

Query: 88  ACAYGHPEVVTLLVERKCEIDARDSESSTALIKAVQCQEEECAAILLDHGADPNVMDSSG 147
           AC+ G  + V  L+ER  +I+  + +  TAL +A      +    L++  AD +V D+ G
Sbjct: 298 ACSSGDRDEVKKLLERGADINTANVDGLTALHQACIDDNLDMVEFLVEQNADVDVCDNEG 119

Query: 148 NTALHYAVYSENTSMAAKLLAHNAN 172
            T LH       T +A  LL + AN
Sbjct: 118 WTPLHATASCGFTEIARYLLENGAN 44

 Score = 39.3 bits (90), Expect = 0.013,   Method: Composition-based stats.
 Identities = 22/73 (30%), Positives = 36/73 (49%)
 Frame = -1

Query: 133 LLDHGADPNVMDSSGNTALHYAVYSENTSMAAKLLAHNANIEAKNKDDLTPMLLAVKENK 192
           LL+ GAD N  +  G TALH A   +N  M   L+  NA+++  + +  TP+        
Sbjct: 262 LLERGADINTANVDGLTALHQACIDDNLDMVEFLVEQNADVDVCDNEGWTPLHATASCGF 83

Query: 193 QHIVEFLVKKKAS 205
             I  +L++  A+
Sbjct: 82  TEIARYLLENGAN 44

 Score = 32.3 bits (72), Expect = 1.5,   Method: Composition-based stats.
 Identities = 20/60 (33%), Positives = 29/60 (48%)
 Frame = -1

Query: 154 AVYSENTSMAAKLLAHNANIEAKNKDDLTPMLLAVKENKQHIVEFLVKKKASIHAVDQLG 213
           A  S +     KLL   A+I   N D LT +  A  ++   +VEFLV++ A +   D  G
Sbjct: 298 ACSSGDRDEVKKLLERGADINTANVDGLTALHQACIDDNLDMVEFLVEQNADVDVCDNEG 119
>15359
          Length = 780

 Score = 43.9 bits (102), Expect = 6e-04,   Method: Compositional matrix adjust.
 Identities = 26/73 (35%), Positives = 37/73 (50%), Gaps = 2/73 (2%)
 Frame = +1

Query: 83  TALHLACAYGHPEVVTLLVER-KCEIDARDSESSTAL-IKAVQCQEEECAAILLDHGADP 140
           TALH A  +G PEVV +L  +   EI+ R     T L + A+   E+    ++  + AD 
Sbjct: 355 TALHWAAKFGKPEVVKMLANKIGVEINQRSHGGYTPLHLAAIHGHEDIIELLVTGYKADA 534

Query: 141 NVMDSSGNTALHY 153
           N+ D SG  A  Y
Sbjct: 535 NIRDYSGKKAKQY 573

 Score = 34.3 bits (77), Expect = 0.45,   Method: Compositional matrix adjust.
 Identities = 23/64 (35%), Positives = 33/64 (51%), Gaps = 3/64 (4%)
 Frame = +1

Query: 51  IHKAASVGDVAKVQHILILGKSGV--NDRDKKDRTALHLACAYGHPEVVTLLVE-RKCEI 107
           +H AA  G    V+  ++  K GV  N R     T LHLA  +GH +++ LLV   K + 
Sbjct: 361 LHWAAKFGKPEVVK--MLANKIGVEINQRSHGGYTPLHLAAIHGHEDIIELLVTGYKADA 534

Query: 108 DARD 111
           + RD
Sbjct: 535 NIRD 546
>33144
          Length = 272

 Score = 40.8 bits (94), Expect = 0.004,   Method: Composition-based stats.
 Identities = 25/71 (35%), Positives = 35/71 (49%), Gaps = 1/71 (1%)
 Frame = +3

Query: 85  LHLACAYGHPEVVTLLVER-KCEIDARDSESSTALIKAVQCQEEECAAILLDHGADPNVM 143
           LHLA   G   +  +LV++ +  ++  D    T L  AVQ  E     +LL   A+PN+ 
Sbjct: 24  LHLAAMNGRTAIAGVLVKKGEVAVNVVDKHKRTPLHYAVQTCELTIIDLLLGRDANPNIQ 203

Query: 144 DSSGNTALHYA 154
           D  GNT  H A
Sbjct: 204 DVDGNTPTHLA 236
>20036
          Length = 1849

 Score = 40.8 bits (94), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 24/72 (33%), Positives = 39/72 (54%), Gaps = 1/72 (1%)
 Frame = +3

Query: 66   ILILGKSGVNDRDKKDRTALHLACAYGHPEVVTLLVER-KCEIDARDSESSTALIKAVQC 124
            +L+   +  N +D    TAL  AC +GH  +V LL+ +  C+    D+E+STAL  A++ 
Sbjct: 1155 LLLETGADCNQQDFDGSTALMCACEHGHTAIVQLLLAQPHCDATLTDNENSTALSIAMEA 1334

Query: 125  QEEECAAILLDH 136
              ++   IL  H
Sbjct: 1335 SHKDIGVILYKH 1370

 Score = 35.4 bits (80), Expect = 0.17,   Method: Compositional matrix adjust.
 Identities = 18/48 (37%), Positives = 28/48 (58%), Gaps = 1/48 (2%)
 Frame = +3

Query: 141 NVMDSSGNTALHYAVYSENTSMAAKLL-AHNANIEAKNKDDLTPMLLA 187
           N++DS+GN+A+HY V   N  +   LL     +++  NK   TP +LA
Sbjct: 867 NLVDSNGNSAIHYCVSHCNFDIVGLLLDTEVCDVKRPNKAGYTPTMLA 1010

 Score = 30.8 bits (68), Expect = 4.7,   Method: Compositional matrix adjust.
 Identities = 25/89 (28%), Positives = 44/89 (49%), Gaps = 1/89 (1%)
 Frame = +3

Query: 82   RTALHLACAYGHPEVVTLLVERKCEIDARDSESSTALIKAVQCQEEECAAILLDHG-ADP 140
            +TAL LA +    ++V LL+E   + + +D + STAL+ A +        +LL     D 
Sbjct: 1104 QTALMLATSQCRTDMVELLLETGADCNQQDFDGSTALMCACEHGHTAIVQLLLAQPHCDA 1283

Query: 141  NVMDSSGNTALHYAVYSENTSMAAKLLAH 169
             + D+  +TAL  A+ + +  +   L  H
Sbjct: 1284 TLTDNENSTALSIAMEASHKDIGVILYKH 1370
>25464
          Length = 440

 Score = 38.9 bits (89), Expect = 0.018,   Method: Composition-based stats.
 Identities = 29/88 (32%), Positives = 44/88 (50%), Gaps = 5/88 (5%)
 Frame = -3

Query: 107 IDARDSESSTALIKA-VQCQEEECAAILLDHGADPNVMDSSGNTALHYAVYSENTS---- 161
           ++ RDS   TAL  A +  +++    IL +   D N  D+ GNT +H+A  S N +    
Sbjct: 432 LNVRDSMGRTALSYACLNGRQDIVRCILKEDVLDINEPDNDGNTPIHHAAISANPNIVRM 253

Query: 162 MAAKLLAHNANIEAKNKDDLTPMLLAVK 189
           +A        N + +NK   TP+LLA K
Sbjct: 252 LAEAFYKFGLNPDKRNKLGYTPLLLACK 169
>30978
          Length = 566

 Score = 38.9 bits (89), Expect = 0.020,   Method: Compositional matrix adjust.
 Identities = 25/66 (37%), Positives = 32/66 (48%), Gaps = 1/66 (1%)
 Frame = -2

Query: 74  VNDRDKKDRTALHLACAYGHPEVV-TLLVERKCEIDARDSESSTALIKAVQCQEEECAAI 132
           VN  DK   T LH A   GH + +  LL E KCE++ ++    TAL  A      E   +
Sbjct: 493 VNGLDKAGSTPLHWAGHGGHMDCLQVLLSEPKCEVNVQNKLGDTALHSAAWKNHVEAVKM 314

Query: 133 LLDHGA 138
           LL  GA
Sbjct: 313 LLGKGA 296
>05396
          Length = 1865

 Score = 38.1 bits (87), Expect = 0.030,   Method: Composition-based stats.
 Identities = 28/81 (34%), Positives = 42/81 (51%), Gaps = 1/81 (1%)
 Frame = +3

Query: 54   AASVGDVAKVQHILILGKSGVNDRDKKDRTALHLACAYGHPEVVTLLVER-KCEIDARDS 112
            +A  GDV  ++   + G   ++  D   RTALH+A A G  +VV  L++R KC     D 
Sbjct: 1305 SAYNGDVTAIRRCALSGMD-MSQPDYDGRTALHVASAEGQLQVVEFLLDRCKCSPFLVDR 1481

Query: 113  ESSTALIKAVQCQEEECAAIL 133
               T L  AV+ ++ E A +L
Sbjct: 1482 WGFTPLDDAVRFEKHEAAELL 1544
>20792
          Length = 441

 Score = 37.4 bits (85), Expect = 0.048,   Method: Composition-based stats.
 Identities = 19/73 (26%), Positives = 35/73 (47%)
 Frame = +2

Query: 82  RTALHLACAYGHPEVVTLLVERKCEIDARDSESSTALIKAVQCQEEECAAILLDHGADPN 141
           +  LH    +G  + +  L++R  ++D       T L+ A    +    ++LL HGADP 
Sbjct: 80  KKPLHETAQFGQLDCMNFLLQRGVQVDCLKRADWTPLMLACTKCQLPVISLLLKHGADPA 259

Query: 142 VMDSSGNTALHYA 154
           +++  G  + H A
Sbjct: 260 LVNKDGWNSFHIA 298
>15772
          Length = 1282

 Score = 37.4 bits (85), Expect = 0.054,   Method: Composition-based stats.
 Identities = 38/159 (23%), Positives = 58/159 (36%), Gaps = 2/159 (1%)
 Frame = -3

Query: 50   KIHKAASVGDVAKVQHILILGKSGVN--DRDKKDRTALHLACAYGHPEVVTLLVERKCEI 107
            ++H AAS GD   ++  +  G   VN  D D  ++TALH AC  G  E            
Sbjct: 1277 ELHDAASTGDYDALEDYVKSGIYDVNLKDPDAGNKTALHWACQKGFVE------------ 1134

Query: 108  DARDSESSTALIKAVQCQEEECAAILLDHGADPNVMDSSGNTALHYAVYSENTSMAAKLL 167
                                 C  +LLDHGA       +G T  H A      +    L 
Sbjct: 1133 ---------------------CIRLLLDHGAKGTARTDTGWTPAHCAAECNRVTALRALH 1017

Query: 168  AHNANIEAKNKDDLTPMLLAVKENKQHIVEFLVKKKASI 206
            A    ++  +K   TP  +A     +    +L++ +A +
Sbjct: 1016 AALVPVDLTDKYGDTPRRIATLYGHRDCARYLLQAEAEV 900
>27108
          Length = 449

 Score = 37.4 bits (85), Expect = 0.057,   Method: Composition-based stats.
 Identities = 31/121 (25%), Positives = 52/121 (42%), Gaps = 22/121 (18%)
 Frame = -3

Query: 53  KAASVGDVAKVQHILILGKSGVNDRDKKDRTALHLACAYGHPEVVTLLVE---------- 102
           +AA   +++ ++H+L +    +N +D    TALH AC +GH E    L++          
Sbjct: 369 RAAIKNNLSLLKHLLTVPGVDINSQDYAGWTALHEACNHGHLECARALLKFVPSATLDSF 190

Query: 103 ----------RKCEIDARDSESSTALIKAVQCQEEECAAILLDHGADPNVMDS--SGNTA 150
                     RK ++   + E  TAL  AV         +LL +G    + D   SG+T 
Sbjct: 189 FQSGKNRGKVRKVDMHLANQEGITALHDAVSMNHVSVVKLLLKYGGSSLLKDKTVSGDTV 10

Query: 151 L 151
           +
Sbjct: 9   M 7
>09180
          Length = 610

 Score = 37.0 bits (84), Expect = 0.063,   Method: Compositional matrix adjust.
 Identities = 32/116 (27%), Positives = 55/116 (47%)
 Frame = +3

Query: 132 ILLDHGADPNVMDSSGNTALHYAVYSENTSMAAKLLAHNANIEAKNKDDLTPMLLAVKEN 191
           +LL  G D N  D+ G T+LH AV+         L+ H  +++ KN    T   LA KE 
Sbjct: 219 VLLQAGVDINAQDADGWTSLHAAVHWGQEDSCQVLVDHFCDMDVKNNAGHTVFDLADKEM 398

Query: 192 KQHIVEFLVKKKASIHAVDQLGSNRQMFEYDGKRLQRSENSNPVDNGSEDGSLTRS 247
            + ++E L KK+A +    +  SN  +    G   +R  +   + +G +   +T++
Sbjct: 399 LK-VLEELKKKQAKLRTASE--SNSDIIHTPGHGSKRRSSVTRMSSGQKQSLITKT 557
>27067
          Length = 409

 Score = 36.6 bits (83), Expect = 0.084,   Method: Composition-based stats.
 Identities = 32/118 (27%), Positives = 57/118 (48%), Gaps = 9/118 (7%)
 Frame = +1

Query: 80  KDRTALHLACAYGHPEVVT-LLVERKCEIDARDSESSTALIKAVQCQEEECAAILLDHGA 138
           K  +A+H A    + +++  LL     E +A ++   T +++A      EC  +LLDHG 
Sbjct: 22  KGSSAVHEAIKVNNTDILRYLLTVPGLECNAVNASQKTPVMEAASRGRIECLTMLLDHGC 201

Query: 139 DPNVMDSSGNTALHYAVYS-----ENTSMAAKL-LAHNA--NIEAKNKDDLTPMLLAV 188
           +    +  G TA+H+ + S     E   M   + L + A  NI A++    +P+ LA+
Sbjct: 202 NTEGENIRGKTAMHHCLLSCGGFVEIEDMVTCMDLVYKAGGNINAQDWFGTSPLHLAI 375
>02055
          Length = 1740

 Score = 35.8 bits (81), Expect = 0.16,   Method: Composition-based stats.
 Identities = 25/83 (30%), Positives = 40/83 (48%), Gaps = 1/83 (1%)
 Frame = +3

Query: 133 LLDHGADPNVMDSSGNTALHYAVYSENTSMAAKLLAHNANIEAKNKD-DLTPMLLAVKEN 191
           L+  GAD +  +  G+T LH A    N      L+ + AN+ A+ K  + TP+ +A +  
Sbjct: 381 LIRCGADVDFCNMFGDTPLHIATVHANHEAMGALVRNGANVNARAKFLNSTPLHVACRLR 560

Query: 192 KQHIVEFLVKKKASIHAVDQLGS 214
            Q  V  L++  A I   D  G+
Sbjct: 561 GQQEVALLIQLGARIDVNDATGT 629
>22305
          Length = 426

 Score = 35.4 bits (80), Expect = 0.20,   Method: Composition-based stats.
 Identities = 19/60 (31%), Positives = 31/60 (51%)
 Frame = -3

Query: 95  EVVTLLVERKCEIDARDSESSTALIKAVQCQEEECAAILLDHGADPNVMDSSGNTALHYA 154
           ++ T L+ER C  + R+      L +A+  +  E   +LL +GADPNV   +    L +A
Sbjct: 343 DITTALLERGCSANERNHWGILPLHEALCWENVEVGRVLLQYGADPNVPCETNVVPLTFA 164
>28113
          Length = 449

 Score = 35.4 bits (80), Expect = 0.21,   Method: Composition-based stats.
 Identities = 22/72 (30%), Positives = 36/72 (50%)
 Frame = -3

Query: 133 LLDHGADPNVMDSSGNTALHYAVYSENTSMAAKLLAHNANIEAKNKDDLTPMLLAVKENK 192
           LL+HG   +  DS    A+HYA +  +  +   LL    +    N + LTP+ +A K+  
Sbjct: 276 LLNHGHHHSKKDSIAWAAIHYASWYGSADVVEILLDAGCSPNLTNSELLTPLHIAAKKGF 97

Query: 193 QHIVEFLVKKKA 204
             + E LV+ +A
Sbjct: 96  PDVAEHLVQAEA 61

 Score = 33.1 bits (74), Expect = 0.96,   Method: Composition-based stats.
 Identities = 28/101 (27%), Positives = 44/101 (43%), Gaps = 1/101 (0%)
 Frame = -3

Query: 80  KDRTALHLACAYGHPEVVTLLVERKCEIDARDSESSTALIKAVQCQEEECAAILLDHGAD 139
           +D+  LH + A G    V  L+        +DS +  A+  A      +   ILLD G  
Sbjct: 336 RDKYPLHASAAQGDVHHVQSLLNHGHHHSKKDSIAWAAIHYASWYGSADVVEILLDAGCS 157

Query: 140 PNVMDSSGNTALHYAVYSENTSMAAKLLAHNA-NIEAKNKD 179
           PN+ +S   T LH A       +A  L+   A ++  ++KD
Sbjct: 156 PNLTNSELLTPLHIAAKKGFPDVAEHLVQAEAIDLNLRDKD 34
>35952
          Length = 1624

 Score = 33.9 bits (76), Expect = 0.51,   Method: Compositional matrix adjust.
 Identities = 21/60 (35%), Positives = 32/60 (53%), Gaps = 1/60 (1%)
 Frame = -1

Query: 146 SGNTALHYAVYSENTSMAAKLLAH-NANIEAKNKDDLTPMLLAVKENKQHIVEFLVKKKA 204
           SG TALH+AV  ++  +A  LL   NA++ A+  D  TP+ +A       +V  L+   A
Sbjct: 976 SGRTALHHAVELDDLPVAGFLLMEANADVNARCFDGNTPLHVACCRGLIGMVALLMTAGA 797
>02351
          Length = 939

 Score = 33.9 bits (76), Expect = 0.57,   Method: Composition-based stats.
 Identities = 27/77 (35%), Positives = 36/77 (46%), Gaps = 5/77 (6%)
 Frame = +3

Query: 66  ILILGKSGVNDRDK---KD--RTALHLACAYGHPEVVTLLVERKCEIDARDSESSTALIK 120
           I+ILG +  +D +    KD  RTALH+A A G+   V LL+     +   D E   AL  
Sbjct: 408 IIILGHAASDDINSPYGKDDGRTALHIAAALGNVVYVQLLLWYCANVKVVDHEGRNALWY 587

Query: 121 AVQCQEEECAAILLDHG 137
           A      EC  +L   G
Sbjct: 588 ARTSGSVECTDLLAAAG 638
>20121
          Length = 454

 Score = 33.1 bits (74), Expect = 0.99,   Method: Compositional matrix adjust.
 Identities = 20/86 (23%), Positives = 40/86 (46%)
 Frame = -1

Query: 51  IHKAASVGDVAKVQHILILGKSGVNDRDKKDRTALHLACAYGHPEVVTLLVERKCEIDAR 110
           IH      +  ++  +L L +  +  +D + RTALHL+ + GH E   +L+    E    
Sbjct: 340 IHWLTWHNNFRELDRLLGLKEHDIETKDPRGRTALHLSVSLGHLESTRVLLRHGAEAGTE 161

Query: 111 DSESSTALIKAVQCQEEECAAILLDH 136
           ++   + L + V   + E   ++L +
Sbjct: 160 NNGCWSVLHEGVCSGDPELVQLILQY 83

 Score = 30.4 bits (67), Expect = 5.5,   Method: Compositional matrix adjust.
 Identities = 19/71 (26%), Positives = 34/71 (47%)
 Frame = -1

Query: 99  LLVERKCEIDARDSESSTALIKAVQCQEEECAAILLDHGADPNVMDSSGNTALHYAVYSE 158
           LL  ++ +I+ +D    TAL  +V     E   +LL HGA+    ++   + LH  V S 
Sbjct: 295 LLGLKEHDIETKDPRGRTALHLSVSLGHLESTRVLLRHGAEAGTENNGCWSVLHEGVCSG 116

Query: 159 NTSMAAKLLAH 169
           +  +   +L +
Sbjct: 115 DPELVQLILQY 83
>30463
          Length = 412

 Score = 32.3 bits (72), Expect = 1.7,   Method: Composition-based stats.
 Identities = 21/65 (32%), Positives = 32/65 (49%)
 Frame = -1

Query: 146 SGNTALHYAVYSENTSMAAKLLAHNANIEAKNKDDLTPMLLAVKENKQHIVEFLVKKKAS 205
           +G TA H A  + +++    L    A+I+ +  D  TP+ LA        V+ LV  KAS
Sbjct: 391 TGYTATHLAAMNGHSNAVMVLNIMGASIDCRTVDKQTPLHLASSAGHIECVKCLVANKAS 212

Query: 206 IHAVD 210
           + A D
Sbjct: 211 LTAED 197

 Score = 31.6 bits (70), Expect = 2.6,   Method: Composition-based stats.
 Identities = 25/78 (32%), Positives = 31/78 (39%), Gaps = 1/78 (1%)
 Frame = -1

Query: 83  TALHLACAYGHPEVVTLLVERKCEIDARDSESSTALIKAVQCQEEECAAILLDHGADPNV 142
           TA HLA   GH   V +L      ID R  +  T L  A      EC   L+ + A    
Sbjct: 382 TATHLAAMNGHSNAVMVLNIMGASIDCRTVDKQTPLHLASSAGHIECVKCLVANKASLTA 203

Query: 143 MDSSGNTALHYA-VYSEN 159
            D+   TA   A  Y +N
Sbjct: 202 EDAFSRTAYDLADQYGQN 149

 Score = 30.0 bits (66), Expect = 9.2,   Method: Composition-based stats.
 Identities = 22/73 (30%), Positives = 35/73 (47%)
 Frame = -1

Query: 51  IHKAASVGDVAKVQHILILGKSGVNDRDKKDRTALHLACAYGHPEVVTLLVERKCEIDAR 110
           +H A+S G +  V+  L+  K+ +   D   RTA  LA  YG  +V   L    C +D  
Sbjct: 277 LHLASSAGHIECVK-CLVANKASLTAEDAFSRTAYDLADQYGQNDVADFL--HHCLLDLD 107

Query: 111 DSESSTALIKAVQ 123
           +  S+ A ++  Q
Sbjct: 106 NPSSTFAQMQLSQ 68
>22269
          Length = 1060

 Score = 32.0 bits (71), Expect = 2.1,   Method: Composition-based stats.
 Identities = 16/33 (48%), Positives = 20/33 (60%), Gaps = 2/33 (6%)
 Frame = +2

Query: 124 CQEE--ECAAILLDHGADPNVMDSSGNTALHYA 154
           CQ+   ECA IL+ HGAD N  D +G + L  A
Sbjct: 329 CQKNNVECARILICHGADYNATDENGESPLFMA 427
>13358
          Length = 775

 Score = 30.8 bits (68), Expect = 4.9,   Method: Compositional matrix adjust.
 Identities = 35/143 (24%), Positives = 64/143 (44%), Gaps = 20/143 (13%)
 Frame = -2

Query: 31  ESASGSHVPRYH----IHDKDMGKIHKAASVGDVAKVQHILILGKS---GVND------R 77
           + A+GS    ++    ++   M ++H+A   GDV  ++ +L    +   G+N       +
Sbjct: 696 DDATGSTTDPFYKYLPLYQDQMNQVHQAVESGDVETLRQLLYFRHNEPHGLNPCLADCRK 517

Query: 78  DKKDRTALHLACAYGHPEVV-----TLLVERKCEIDA-RDSESSTALIKAV-QCQEEECA 130
               +  LH A   G  E++     TL+ +RK  +D+ RD    T L  A  Q   ++  
Sbjct: 516 PGDGQPLLHKAALRGSYEMLELLAETLVYQRKQRLDSIRDQHFRTCLHYAYGQEHGKQLV 337

Query: 131 AILLDHGADPNVMDSSGNTALHY 153
            +L+D+GA    MD    + L +
Sbjct: 336 NLLMDYGASEFTMDKDNRSPLCF 268
>09214
          Length = 2116

 Score = 30.4 bits (67), Expect = 6.7,   Method: Compositional matrix adjust.
 Identities = 28/102 (27%), Positives = 46/102 (45%), Gaps = 2/102 (1%)
 Frame = -3

Query: 88   ACAYGHPEVVTLLVERK-CEIDARDSESS-TALIKAVQCQEEECAAILLDHGADPNVMDS 145
            +C Y    V   LVE K  +++A++  +  TAL    +   +     LL HGAD N +D+
Sbjct: 1694 SCQYW*HGVAKKLVEVKNVDVNAQNKMNGRTALHWGAKRDHQTVVQYLLSHGADKNAVDN 1515

Query: 146  SGNTALHYAVYSENTSMAAKLLAHNANIEAKNKDDLTPMLLA 187
             G  A      S+       LL  + ++  + +  +TP  LA
Sbjct: 1514 DGKIAGQLTTNSD----VHTLLGGSGDVTNQEQLPITPSYLA 1401
>28743
          Length = 612

 Score = 30.0 bits (66), Expect = 7.6,   Method: Compositional matrix adjust.
 Identities = 26/70 (37%), Positives = 39/70 (55%), Gaps = 2/70 (2%)
 Frame = -3

Query: 1227 EAR--DLKKKLGQLRSQLQEARDQHREAVHHAEKMEDHLQKLELEKSKFEITIKKQSEEI 1284
            EAR  +L ++L     +  EA  Q REA+  AE          LEK + EI ++ + EE+
Sbjct: 211  EARLTELARRLNDTEHRENEALQQVREAITMAETSV-------LEKDQAEIQMRHKDEEV 53

Query: 1285 DQLQENLSRV 1294
             QLQE+LS++
Sbjct: 52   SQLQESLSKI 23
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|91992157|ref|NP_001035195.1| AP2 associated kinase 1
isoform 1 [Mus musculus]
         (959 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

18921                                                                  77   3e-14
13592                                                                  70   3e-12
17982                                                                  70   4e-12
29581                                                                  70   5e-12
01707                                                                  68   2e-11
00300                                                                  68   2e-11
12721                                                                  68   2e-11
01756                                                                  64   2e-10
14126                                                                  59   9e-09
01060                                                                  57   4e-08
14420                                                                  54   2e-07
19761                                                                  54   3e-07
13212                                                                  52   9e-07
26560                                                                  50   3e-06
11780                                                                  50   6e-06
06405                                                                  50   6e-06
31885                                                                  49   7e-06
19094                                                                  49   1e-05
17253                                                                  47   3e-05
01966                                                                  47   3e-05
15910                                                                  47   4e-05
04138                                                                  47   5e-05
03240                                                                  46   6e-05
18484                                                                  45   1e-04
09606                                                                  45   1e-04
04591                                                                  45   1e-04
09007                                                                  45   1e-04
14116                                                                  45   1e-04
04852                                                                  45   2e-04
30755                                                                  44   2e-04
26711                                                                  44   3e-04
01392                                                                  43   7e-04
07291                                                                  43   7e-04
12786                                                                  42   9e-04
13066                                                                  42   0.001
07836                                                                  42   0.002
01718                                                                  41   0.002
37602                                                                  39   0.009
28157                                                                  39   0.010
21808                                                                  39   0.010
00392                                                                  39   0.014
21079                                                                  39   0.015
28638                                                                  38   0.015
11185                                                                  38   0.023
38560                                                                  37   0.031
07940                                                                  37   0.036
27546                                                                  37   0.044
20655                                                                  37   0.052
17975                                                                  37   0.052
27405                                                                  37   0.054
12672                                                                  37   0.054
07833                                                                  36   0.057
21433                                                                  36   0.071
00715                                                                  36   0.081
03508                                                                  36   0.082
18996                                                                  35   0.12 
17300                                                                  33   0.62 
03106                                                                  32   0.84 
32000                                                                  32   0.94 
19301                                                                  32   1.3  
20152                                                                  31   2.1  
02638                                                                  29   7.2  
>18921
          Length = 697

 Score = 77.0 bits (188), Expect = 3e-14,   Method: Compositional matrix adjust.
 Identities = 66/203 (32%), Positives = 96/203 (47%), Gaps = 5/203 (2%)
 Frame = +2

Query: 52  LAEGGFALVFL-VRTSNGVKCALKRMFVNNEHDLQVCKREIQIMRDLSGHKNIVGYIDSS 110
           L EG +  VF  +    G   A+K++ V+   DLQ   +EI IM+     K IV Y  S 
Sbjct: 53  LGEGSYGSVFKSLHKETGQVLAIKQVPVDT--DLQEIIKEISIMQQCDS-KYIVKYYGSY 223

Query: 111 INNVSSGDVWEVLILMDFCRGGQVVNLMNQRLQTGFTENEVLQIFCDTCEAVARLHQCKT 170
             N    D+W   I+M++C  G V ++M  R +T   E E+  I   T + +  LH  + 
Sbjct: 224 FKNT---DLW---IVMEYCGAGSVSDIMRLRNKT-LVEREIATILYYTLKGLXYLHSRRK 382

Query: 171 PIIHRDLKVENILLHDRGHYVLCDFGSATNKFQNPQAEGVNAVEDEIKKYTTL----SYR 226
             IHRD+K  NILL++ GH  L DFG A              + D + K  T+     + 
Sbjct: 383 --IHRDIKAGNILLNNEGHAKLADFGVA------------GQLTDTMAKRNTVIGTPYWM 520

Query: 227 APEMVNLYSGKIITTKADIWALG 249
           APE++       +   ADIW+LG
Sbjct: 521 APEVIQEIGYDCV---ADIWSLG 580
>13592
          Length = 980

 Score = 70.5 bits (171), Expect = 3e-12,   Method: Compositional matrix adjust.
 Identities = 71/260 (27%), Positives = 116/260 (44%), Gaps = 10/260 (3%)
 Frame = +2

Query: 52  LAEGGFALVFL-VRTSNGVKCALKRMFV--NNEHDLQVCKREIQIMRDLSGHKNIVGYID 108
           + +G F  V+  V  + G   A+K + +       L+    E++I+  +  HKN+V Y  
Sbjct: 8   IGQGRFGKVYTAVNNNTGELMAMKEIAIQPGETRALKNVAEELKILEGIK-HKNLVRYYG 184

Query: 109 SSINNVSSGDVWEVLILMDFCRGGQVVNLMNQRLQTGFTENEVLQIFCDTCEAVARLHQC 168
             ++        E+LI M+ C  G + +L+   L  G  E    +        VA LH  
Sbjct: 185 IEVHRE------ELLIFMELCSEGTLESLV--ELTGGLPEALSRRFTAQLLSGVAELH-- 334

Query: 169 KTPIIHRDLKVENILLHDRGHYV-LCDFGSATNKFQNPQAEGVNAVEDEIKKYT-TLSYR 226
           K  I+HRD+K  NI L D  + + L DFGSA       + +    V  E++ Y  T +Y 
Sbjct: 335 KHGIVHRDIKTANIFLVDGSNSLKLGDFGSAV------KIQAHTTVPGELQGYVGTQAYM 496

Query: 227 APEMVNLYSGKIITTKADIWALGCLLYKLCYFTLPFGE----SQVAICDGSFTIPDN-SR 281
           APE+    +       ADIW++GC++ ++     P+ +     Q+    G    P     
Sbjct: 497 APEVFTKTNSDGHGRLADIWSVGCVVVEMASGKRPWAQFDSNFQIMFKVGMGEKPQAPES 676

Query: 282 YSQDMHCLIRYMLEPDPDKR 301
            SQ+ H  I + L+ DP +R
Sbjct: 677 LSQEGHDFIDHCLQHDPKQR 736
>17982
          Length = 477

 Score = 70.1 bits (170), Expect = 4e-12,   Method: Composition-based stats.
 Identities = 37/105 (35%), Positives = 62/105 (59%), Gaps = 3/105 (2%)
 Frame = -1

Query: 34  YIGRVFGIGRQQVTVDEVLAEGGFALVFLVRTSN-GVKCALKRMFVNNEHDLQVCKREIQ 92
           ++G+   +G Q++ V  ++AEGGFA VF+ +  N G   ALKR+  N+E + +    EI+
Sbjct: 315 FVGQYVELGNQKLRVKRLIAEGGFAFVFVAQDVNSGKDYALKRLLANDEENSKAIMDEIK 136

Query: 93  IMRDLSGHKNIVGYIDSSINNVSSGD--VWEVLILMDFCRGGQVV 135
            ++ LSGH +I+ +I ++       D    E L+L + C GGQ+V
Sbjct: 135 YLKKLSGHPHIIQFITAASIGKDQSDHGQSEFLLLTELCSGGQLV 1
>29581
          Length = 1278

 Score = 69.7 bits (169), Expect = 5e-12,   Method: Compositional matrix adjust.
 Identities = 54/157 (34%), Positives = 78/157 (49%), Gaps = 1/157 (0%)
 Frame = -2

Query: 100  HKNIVGYIDSSINNVSSGDVWEVLIL-MDFCRGGQVVNLMNQRLQTGFTENEVLQIFCDT 158
            H+NIV      +  V  G   + L L M++C       L N  +   F+E++V  I    
Sbjct: 1178 HQNIV-----QLQEVVVGKSLDSLFLVMEYCEQDLASLLDN--MPAPFSESQVKCIVLQL 1020

Query: 159  CEAVARLHQCKTPIIHRDLKVENILLHDRGHYVLCDFGSATNKFQNPQAEGVNAVEDEIK 218
             + +  LH+    IIHRDLKV N+L+ D+G   + DFG A N +  PQ      V     
Sbjct: 1019 LKGLRYLHEAF--IIHRDLKVSNLLMTDKGCVKIADFGLARN-YGKPQKPMTPKV----- 864

Query: 219  KYTTLSYRAPEMVNLYSGKIITTKADIWALGCLLYKL 255
               TL YRAPE+  L+  K  +T  D+W+ GC+L +L
Sbjct: 863  --VTLWYRAPEL--LFGSKTHSTAIDMWSAGCILGEL 765
>01707
          Length = 757

 Score = 67.8 bits (164), Expect = 2e-11,   Method: Composition-based stats.
 Identities = 63/210 (30%), Positives = 93/210 (44%), Gaps = 6/210 (2%)
 Frame = +1

Query: 52  LAEGGFALVFLVRTSNGVKCALKRMFVNNEHD---LQVCKREIQIMRDLSGHKNIVGYID 108
           + EG + +VF  R     +    + FV +E D    ++  REI++++ L  H N+V  I+
Sbjct: 88  IGEGSYGVVFKCRNKETSQLVAIKKFVESEDDPLIKKIAMREIRMLKQLK-HPNLVRLIE 264

Query: 109 SSINNVSSGDVWEVLILMDFCRGGQVVNLMNQ--RLQTGFTENEVLQIFCDTCEAVARLH 166
                        + ++ D+        L+N+  R   G  E  V +I   T  AV   H
Sbjct: 265 VFRRKK------RLHLVFDYVDH----TLLNELDRYPRGLPEPMVKRIIYQTLLAVNFCH 414

Query: 167 QCKTPIIHRDLKVENILLHDRGHYVLCDFGSATNKFQNPQAEGVNAVEDEIKKY-TTLSY 225
           Q  T  IHRD+K ENIL+  +G   LCDFG          A  +    DE   Y  T  Y
Sbjct: 415 QYNT--IHRDVKPENILITRQGQVKLCDFGF---------ARILTGPGDEYTDYVATRWY 561

Query: 226 RAPEMVNLYSGKIITTKADIWALGCLLYKL 255
           RAPE+  L          D+WA+GC+  +L
Sbjct: 562 RAPEL--LVGDTQYGPPVDVWAIGCVFAEL 645
>00300
          Length = 2318

 Score = 67.8 bits (164), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 60/215 (27%), Positives = 93/215 (43%), Gaps = 4/215 (1%)
 Frame = -1

Query: 52   LAEGGFALVFL-VRTSNGVKCALKRMFV--NNEHDLQVCKREIQIMRDLSGHKNIVGYID 108
            + EG F  V+  V  S G   ALK M    N+   L+    EI+I   +  H+N+V Y  
Sbjct: 1634 IGEGQFGKVYTAVNMSTGELMALKEMKFQPNDLQQLREMCDEIKIFEGIQ-HENLVKYYG 1458

Query: 109  SSINNVSSGDVWEVLILMDFCRGGQVVNLMNQRLQTGFTENEVLQIFCDTCEAVARLHQC 168
              ++        E+L+ M++C  G +     +  + G  E  + +   +   AV  LH+ 
Sbjct: 1457 VEVHKD------EMLMFMEYCDTGTI----EEAAKMGLPEYLIRRYTREIVLAVNHLHE- 1311

Query: 169  KTPIIHRDLKVENILLHDRGHYVLCDFGSATNKFQNPQAEGVNAVEDEIKKYT-TLSYRA 227
               I+HRD+K  NI L   GH  L DFG +     +    G      E      T +Y A
Sbjct: 1310 -NSIVHRDIKGANIFLTSNGHVKLGDFGCSVKLKSHTTMPG------EFHNLVGTTAYMA 1152

Query: 228  PEMVNLYSGKIITTKADIWALGCLLYKLCYFTLPF 262
            PE+            ADIW+LGC++ ++     P+
Sbjct: 1151 PEVFTQNDQGGYGRAADIWSLGCVVIEMATGKRPW 1047
>12721
          Length = 821

 Score = 67.8 bits (164), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 59/214 (27%), Positives = 103/214 (48%), Gaps = 3/214 (1%)
 Frame = +1

Query: 52  LAEGGFALVFLVRTSNGVKCALKRMFVNNEHDLQVCKREIQIMRDLSGHKNIVGYIDSSI 111
           + EG   +V +  + +G + A+K+M +  +   ++   E+ +MRD   H NIV   +S +
Sbjct: 112 IGEGSTGIVCIATSRDGRQMAVKKMDLRKQQRRELLFNEVVVMRDYH-HPNIVEMYNSYL 288

Query: 112 NNVSSGDVWEVLILMDFCRGGQVVNLM-NQRLQTGFTENEV-LQIFCDTC-EAVARLHQC 168
            N    ++W   ++M+F  GG + +++ N R+      +EV +   C  C +A+A LH  
Sbjct: 289 VN---DELW---VVMEFMEGGALTDIVTNNRM------DEVQIATVCRACLKALAFLH-- 426

Query: 169 KTPIIHRDLKVENILLHDRGHYVLCDFGSATNKFQNPQAEGVNAVEDEIKKYTTLSYRAP 228
              +IHRD+K ++ILL   G   L DFG      Q+ Q               T  + AP
Sbjct: 427 ANGVIHRDIKSDSILLSHDGKVKLXDFGFCAQVTQDLQKRK--------SLVGTPYWMAP 582

Query: 229 EMVNLYSGKIITTKADIWALGCLLYKLCYFTLPF 262
           E++   S      + DIW+LG ++ ++     PF
Sbjct: 583 EVI---SRLPYGPEVDIWSLGIMVMEMIDAEPPF 675
>01756
          Length = 1858

 Score = 64.3 bits (155), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 56/208 (26%), Positives = 98/208 (47%), Gaps = 7/208 (3%)
 Frame = -3

Query: 52   LAEGGFALVFLVRTSNGVKC-ALKRMFVNNEHDL--QVCKREIQIMRDLSGHKNIVGYID 108
            + +G F  VF  R     +  A+K++ ++NE +       REI+I++ L  H+N+V  I+
Sbjct: 1718 IGQGTFGEVFKARCKKTKQVVAMKKVLMDNEKEGFPITALREIKILQ-LLNHENVVDLIE 1542

Query: 109  SSINNVSSGDVWEVL--ILMDFCRGGQVVNLMNQRLQTGFTENEVLQIFCDTCEAVARLH 166
                  +S + ++ +  ++ +FC       L N  +   F   E+ ++       +  +H
Sbjct: 1541 ICSTKATSANRYKSMFYLVFEFCEHDLAGLLSN--MSVVFNLPEIKEVMKQLMNGLYYIH 1368

Query: 167  QCKTPIIHRDLKVENILLHDRGHYVLCDFGSATNKFQNPQAEGVNAVE--DEIKKYTTLS 224
            + K  I+HRD+K  NIL+  +G   L DFG A       +A  VN  +      +  TL 
Sbjct: 1367 RNK--ILHRDMKAANILITKQGVLKLADFGLA-------RAFSVNLRQPNRYTNRVVTLW 1215

Query: 225  YRAPEMVNLYSGKIITTKADIWALGCLL 252
            YR PE+  L   +  +T  D W  GC++
Sbjct: 1214 YRPPEL--LLGDRNYSTAIDQWGAGCIM 1137
>14126
          Length = 1265

 Score = 58.9 bits (141), Expect = 9e-09,   Method: Compositional matrix adjust.
 Identities = 56/219 (25%), Positives = 91/219 (41%), Gaps = 14/219 (6%)
 Frame = +3

Query: 51  VLAEGGFALVFLVR--TSNGVKCALKRMFVNNEHDLQ--VCKREIQIMRDLSG--HKNIV 104
           V+  G +  V+  R   + G   A+KR+ +NN  +    +  REI +++ L    H N+V
Sbjct: 210 VIGNGAYGTVYKARDLRNQGEFVAMKRIRLNNTEEGMPMMAIREISMLKQLEQYEHPNVV 389

Query: 105 GYIDSSINNVSSGDVWEVLILMDFCRGGQVVNLMNQRLQT--------GFTENEVLQIFC 156
             +D S N ++  ++          R   V   +   L T        G   + +  +  
Sbjct: 390 RLLDVSHNTITDREI----------RLNLVFEYIEHDLATYLAKCPSPGLGPDRIKDLML 539

Query: 157 DTCEAVARLHQCKTPIIHRDLKVENILLHDRGHYVLCDFGSATNKFQNPQAEGVNAVEDE 216
                V  LH  +  I+HRDLK +N+L+   G   L DFG A  +  +        V   
Sbjct: 540 QLLNGVDFLHSNR--IVHRDLKPQNLLISKDGRLKLADFGLA--RIYSFHMALTTVV--- 698

Query: 217 IKKYTTLSYRAPEMVNLYSGKIITTKADIWALGCLLYKL 255
                TL YR+PE++         T  DIW+ GC+  +L
Sbjct: 699 ----VTLWYRSPEVLMQAE---YGTSVDIWSCGCIFAEL 794
>01060
          Length = 1800

 Score = 57.0 bits (136), Expect = 4e-08,   Method: Compositional matrix adjust.
 Identities = 67/226 (29%), Positives = 106/226 (46%), Gaps = 10/226 (4%)
 Frame = +1

Query: 52  LAEGGFALVFLVR-TSNGVKCALKRMFVNNEHDL--QVCKREIQIMRDLSGHKNIVGYID 108
           + EG + +V+  R  + G K A+K++ +    D       REI ++R+L  H NIV   D
Sbjct: 97  IGEGTYGVVYKCRHRATGRKLAMKKIRLRGSEDGVPSSAIREIAMLRELR-HTNIVCLED 273

Query: 109 SSINNVSSGDVWEVL-----ILMDFCRGGQVVNLMNQRLQTGFTENEVLQI-FCDTCEAV 162
             + +     V+E L     + +D    G V   +++RL   +    V  I FC      
Sbjct: 274 VIMEDERLFLVFEFLSMDLKMYIDKFPEGVV---LDRRLVKSYVFQIVTGIXFC------ 426

Query: 163 ARLHQCKTPIIHRDLKVENILLHDRGHYVLCDFGSATNKFQNPQAEGVNAVEDEIKKYTT 222
              HQ +  I+HRDLK +N+L++  G   + DFG A   F  P    V A   E+    T
Sbjct: 427 ---HQRR--IVHRDLKPQNLLINHTGAIKIADFGMART-FALP----VRAYTHEV---VT 567

Query: 223 LSYRAPEMVNLYSGKIITTKADIWALGCLLYKLCYFTLPF-GESQV 267
           L YRAPE+  L      +T  D+W++G +   +   T  F G+S++
Sbjct: 568 LWYRAPEI--LMGASKYSTPVDVWSIGTIFADMLIRTPIFKGDSEI 699
>14420
          Length = 528

 Score = 54.3 bits (129), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 48/170 (28%), Positives = 84/170 (49%), Gaps = 4/170 (2%)
 Frame = +2

Query: 90  EIQIMRDLSGHKNIVGYIDSSINNVSSGDVWEVLILMDFCRGGQVVNLMNQRLQTGFTEN 149
           EI +MR+ + + NIV Y+DS +     G+  E+ ++M+F  GG + +++ +   T   E 
Sbjct: 50  EILVMRE-NQNPNIVNYLDSYL----VGE--ELWVVMEFLAGGSLTDVVTE---TCMDEG 199

Query: 150 EVLQIFCDTCEAVARLHQCKTPIIHRDLKVENILLHDRGHYVLCDFGSATNKFQNPQAEG 209
           ++  +  +  +A+  LH+    +IHRD+K +NILL   G   L DFG             
Sbjct: 200 QIAAVCRECLQALEFLHE--NQVIHRDIKSDNILLGMDGSVKLTDFGFCAQ--------- 346

Query: 210 VNAVEDEIKKYTTL----SYRAPEMVNLYSGKIITTKADIWALGCLLYKL 255
              +  E  K +T+     + APE+V   + K      DIW+LG +  ++
Sbjct: 347 ---LSPEQSKRSTMVGTPYWMAPEVV---TRKQYGPTVDIWSLGVMCIEM 478
>19761
          Length = 473

 Score = 54.3 bits (129), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 45/159 (28%), Positives = 70/159 (44%), Gaps = 6/159 (3%)
 Frame = -3

Query: 145 GFTENEVLQIFCDTCEAVARLHQCKTPIIHRDLKVENILLHDRGHYVLCDFGSATNKFQN 204
           G  E  ++     T  A+  +H     I+HRDLK +NI + ++G   L D G A  K   
Sbjct: 435 GLPERLIVCWLMQTASALNYMHTHTPVILHRDLKPQNIYVTEKGDVRLGDLGLA-RKLTG 259

Query: 205 PQAEGVNAVEDEIKKYTTLSYRAPEMVNLYSGKIITTKADIWALGCLLYKLCYFTLPFGE 264
           P     + V        T+ Y +PE++   S +   +K+DIW+LGC+ Y +   T   G 
Sbjct: 258 PADFATSQV-------GTIMYLSPEIL---SQQPYNSKSDIWSLGCVFYDI---TGKKGS 118

Query: 265 SQVAI------CDGSFTIPDNSRYSQDMHCLIRYMLEPD 297
            ++ +        G   +P    YSQ+    I  ML  D
Sbjct: 117 DEMGVMFLLVQVMGGRKLPLPDHYSQEFRDTISRMLTKD 1
>13212
          Length = 1067

 Score = 52.4 bits (124), Expect = 9e-07,   Method: Compositional matrix adjust.
 Identities = 42/148 (28%), Positives = 64/148 (43%), Gaps = 2/148 (1%)
 Frame = -1

Query: 119  VWEVLILMDFCRGGQVVNLMNQRLQTGFTENEVLQIFCDTCEAVARLHQCKTPIIHRDLK 178
            VW ++ +      G + ++M   L+   TE ++  +  + C A+  LH+    +IHRD+K
Sbjct: 1067 VWXIVDVFRVLWWGALDSIMVD-LEKPMTEAQICYVCHEMCMALDFLHRHH--VIHRDIK 897

Query: 179  VENILLHDRGHYVLCDFGSATNKFQNPQAEGVNAVEDEIKKYTTLSYRAPEMVNLYSGKI 238
              N+LL   G   L DFG +    Q  Q               T  + APE+V   + K 
Sbjct: 896  AGNVLLTIDGEVKLADFGVSAKNTQTQQKRDTF--------IGTPYWMAPEVVLCETLKD 741

Query: 239  I--TTKADIWALGCLLYKLCYFTLPFGE 264
                 KADIW+LG  L +      P  E
Sbjct: 740  TPYDFKADIWSLGVTLIEFAQIEPPNKE 657
>26560
          Length = 398

 Score = 50.4 bits (119), Expect = 3e-06,   Method: Composition-based stats.
 Identities = 38/118 (32%), Positives = 54/118 (45%), Gaps = 1/118 (0%)
 Frame = -1

Query: 146 FTENEVLQIFCDTCEAVARLHQCKTPIIHRDLKVENILLHDRGHYVLCDFGSATN-KFQN 204
           FTE EV     +    +  +H     +++RDLK  NILL + GH  + D G A +   + 
Sbjct: 365 FTEKEVRFYAAEVMLGLEHMHS--RFVVYRDLKPANILLDENGHVRISDLGLACDFSKKR 192

Query: 205 PQAEGVNAVEDEIKKYTTLSYRAPEMVNLYSGKIITTKADIWALGCLLYKLCYFTLPF 262
           P A              T  Y APE+  L  G+   + AD ++ GC+LYKL     PF
Sbjct: 191 PHAS-----------VGTHGYMAPEV--LMKGQSYDSSADWFSFGCMLYKLLKGHSPF 57
>11780
          Length = 1713

 Score = 49.7 bits (117), Expect = 6e-06,   Method: Compositional matrix adjust.
 Identities = 40/158 (25%), Positives = 72/158 (45%)
 Frame = +3

Query: 41  IGRQQVTVDEVLAEGGFALVFLVRTSNGVKCALKRMFVNNEHDLQVCKREIQIMRDLSGH 100
           I  Q + + E + +G F  V+      G   A+K++  + +   Q   +E  +M  L  H
Sbjct: 588 IAXQDLEIGEAIGKGDFGDVY-KGMYRGQPVAIKQL-KDKDRGEQSFLQEASVMTSLR-H 758

Query: 101 KNIVGYIDSSINNVSSGDVWEVLILMDFCRGGQVVNLMNQRLQTGFTENEVLQIFCDTCE 160
            N+V  I   +          + ++ +F   G +V  +  R ++  T+ + +    DTC 
Sbjct: 759 DNLVRLIGVVLGET-------IFLVTEFMGKGNLVEYLRSRGRSVITKKDQINFATDTCA 917

Query: 161 AVARLHQCKTPIIHRDLKVENILLHDRGHYVLCDFGSA 198
           A+  L   +  ++HRDL   N+L+HD G   + DFG A
Sbjct: 918 AMEYLESKR--LVHRDLAARNVLVHDDGKAKVSDFGLA 1025
>06405
          Length = 1965

 Score = 49.7 bits (117), Expect = 6e-06,   Method: Compositional matrix adjust.
 Identities = 77/391 (19%), Positives = 140/391 (35%), Gaps = 10/391 (2%)
 Frame = +1

Query: 39  FGIGRQQVTVDEVLAEGGFALVFLVRTSNGVKCALKRMFVNNEHDLQVCKREIQIMRDLS 98
           + I R ++ +   L  G +  V+        K    +    +   L     E  IM+++ 
Sbjct: 244 WEIERTEIAMKHRLGGGQYGDVYEAMWKRYNKIVAVKTLKEDTMALNDFLEEAAIMKEMK 423

Query: 99  GHKNIVGYIDSSINNVSSGDVWEVLILMDFCRGGQVVNLMNQRLQTGFTENEVLQIFCDT 158
            H N+V  +                I+ +F   G +++ +    +       ++ +    
Sbjct: 424 -HPNLVQLLGVCTREPP------FYIVTEFMPHGNLLDYLRSSTREENGPTALMYMATQI 582

Query: 159 CEAVARLHQCKTPIIHRDLKVENILLHDRGHYVLCDFGSATNKFQNPQAEGVNAVEDEIK 218
              +A L       IHRDL   N L+ D     + DFG A     +     + A      
Sbjct: 583 ASGMAYLETKN--FIHRDLAARNCLVADSNMVKVADFGLARLMKDDTYTAHIGA------ 738

Query: 219 KYTTLSYRAPEMVNLYSGKIITTKADIWALGCLLYKLCYFTL-PFGESQVA----ICDGS 273
           K+  + + APE +        +T++DIWA G LL++L  + + P+   ++     + +  
Sbjct: 739 KF-PIKWTAPEGLAF---NRFSTRSDIWAFGVLLWELATYGMSPYPGVELTEVYHLLERG 906

Query: 274 FTIPDNSRYSQDMHCLIRYMLEPDPDKRPDIYQVSYFSFKLLKKECPVPNVQNSPIPAKL 333
           + +        D++ L+    + DP  RP   ++ +    + +K      V+        
Sbjct: 907 YRMERPPGTPADVYILMLKCWQWDPKDRPTFKEIHFLLENMFEKSSICEEVE-------- 1062

Query: 334 PEPVKASEAAVKKTQPKARLTDPIPTTET----SIAPRQRPKAGQTQPNPGILPIQPALT 389
               K  E   KK  P      P P  +T    S AP   P+   TQ             
Sbjct: 1063----KELEKNDKKQMP------PCPPRKTGSPLSTAPTSHPRGPPTQGR----------- 1179

Query: 390 PRKRATVQPLPQAAGPS-NQPGLLPSVSQPK 419
            R + TV P P+   P+ N P     V+ P+
Sbjct: 1180-RHQPTVAPCPRWKKPTLNSPPTASPVNHPR 1269
>31885
          Length = 529

 Score = 49.3 bits (116), Expect = 7e-06,   Method: Composition-based stats.
 Identities = 46/149 (30%), Positives = 69/149 (46%), Gaps = 4/149 (2%)
 Frame = -2

Query: 118 DVWEVLILMDFCRGGQVVNLMNQRLQTGFTENEVLQIFCDTCEAVARLHQCKTPIIHRDL 177
           D  ++ +++D   GG +   M Q  +  F E+ V    C     +  L   K  I+HRD+
Sbjct: 459 DEEDLFMVVDLFLGGDLRYHMQQ--EVSFREDCVKFYLCQLALVLDYLRSQK--IVHRDI 292

Query: 178 KVENILLHDRGHYVLCDFGSATNKFQNPQAEGVNAVEDEIKKYT--TLSYRAPEM--VNL 233
           K +NILL ++GH  + DF  AT      Q E     +DE+   T  T  Y APE+  V +
Sbjct: 291 KPDNILLDEQGHCHVTDFNIAT------QLE-----DDELATSTSGTRPYMAPEVYGVAI 145

Query: 234 YSGKIITTKADIWALGCLLYKLCYFTLPF 262
              +      D W+LG  L++L     PF
Sbjct: 144 NERRGYGFPVDWWSLGVSLFELLKKRRPF 58
>19094
          Length = 898

 Score = 48.5 bits (114), Expect = 1e-05,   Method: Composition-based stats.
 Identities = 39/123 (31%), Positives = 57/123 (46%), Gaps = 4/123 (3%)
 Frame = +1

Query: 131 GGQVVNLMNQRLQTGFTENEVLQIFCDTCEAVARLHQCKTPIIHRDLKVENILLHDRGHY 190
            G V ++M  R +T   E E+  I   T + +  LH  +   IHRD+K  NILL++ GH 
Sbjct: 7   AGSVSDIMRLRNKT-LVEREIATILYYTLKGL*YLHSRRK--IHRDIKAGNILLNNEGHA 177

Query: 191 VLCDFGSATNKFQNPQAEGVNAVEDEIKKYTTL----SYRAPEMVNLYSGKIITTKADIW 246
            L DFG A              + D + K  T+     + APE++       +   ADIW
Sbjct: 178 KLADFGVA------------GQLTDTMAKRNTVIGTPYWMAPEVIQEIGYDCV---ADIW 312

Query: 247 ALG 249
           +LG
Sbjct: 313 SLG 321
>17253
          Length = 483

 Score = 47.4 bits (111), Expect = 3e-05,   Method: Composition-based stats.
 Identities = 33/116 (28%), Positives = 53/116 (45%), Gaps = 8/116 (6%)
 Frame = -1

Query: 89  REIQIMRDLSGHKNIVGYIDSSINNVSSGDVWEVLILMDFCRGGQVVNLMNQR------L 142
           RE+ IMR L  H N+V ++     +  +      LILM+FC  G +++ + +R       
Sbjct: 402 RELSIMRKLPRHPNVVSFMGCCTMSDPA------LILMEFCCHGDLLSFLRKRRPDRTVF 241

Query: 143 QTGFTENEVLQIFCDTCEAVAR--LHQCKTPIIHRDLKVENILLHDRGHYVLCDFG 196
            T    +   + F      VAR   H     I+HRD+   N+L+ +R    + DFG
Sbjct: 240 LTSTANDLTARDFFSFALHVARGMAHVANNKIVHRDVAARNVLISERNVCKVSDFG 73
>01966
          Length = 1735

 Score = 47.4 bits (111), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 54/174 (31%), Positives = 81/174 (46%), Gaps = 8/174 (4%)
 Frame = -1

Query: 66   SNGVKCALKRMFVNNEHDL--QVCKREIQIMRDLSGHKNIVGYIDSSINNVSSGDVWEVL 123
            + G K A+K++ +    D       REI ++R+L  H NIV   D  + +     V+E L
Sbjct: 1642 ATGRKLAMKKIRLRGSEDGVPSSAIREIAMLRELR-HTNIVCLEDVIMEDERLFLVFEFL 1466

Query: 124  -----ILMDFCRGGQVVNLMNQRLQTGFTENEVLQI-FCDTCEAVARLHQCKTPIIHRDL 177
                 + +D    G V   +++RL   +    V  I FC         HQ +  I+HRDL
Sbjct: 1465 SMDLKMYIDKFPEGVV---LDRRLVKSYVFQIVTGINFC---------HQRR--IVHRDL 1328

Query: 178  KVENILLHDRGHYVLCDFGSATNKFQNPQAEGVNAVEDEIKKYTTLSYRAPEMV 231
            K +N+L++  G   + DFG A   F  P    V A   E+    TL YRAPE++
Sbjct: 1327 KPQNLLINHTGAIKIADFGMA-RTFALP----VRAYTHEV---VTLWYRAPEIL 1190
>15910
          Length = 1361

 Score = 47.0 bits (110), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 49/184 (26%), Positives = 81/184 (44%), Gaps = 14/184 (7%)
 Frame = +2

Query: 132 GQVVNLMNQRLQTG-FTENEVLQIFCDTCEAVARLHQCKTPIIHRDLKVENIL---LHDR 187
           G+   L ++ +  G +TE +  +   D    V  +H     ++HRDLK EN+L   + D 
Sbjct: 410 GEWWELFDRIVTRGQYTEKDAARAISDILHGVQYIHA--NGVVHRDLKPENLLYECMTDD 583

Query: 188 GHYVLCDFGSATNKFQNPQAEGVNAVEDEIKKYT---TLSYRAPEMVNLYSGKIITTKAD 244
               L DFG +              +E E++  T   T  Y APE++    G   T   D
Sbjct: 584 SKLKLADFGLS------------RIIEPEVQMSTVCGTPGYCAPEVLK---GDKYTPSVD 718

Query: 245 IWALGCLLY-KLCYFTLPFGESQV----AICDGSFTIPDN--SRYSQDMHCLIRYMLEPD 297
           +W++G + Y  LC +   F E++      I  G +   +   S  S++   ++R +L  D
Sbjct: 719 MWSVGVIAYILLCGYEPFFAENEFEMYRKIIKGEYKFDEEYWSEISENAKDVVRKLLVID 898

Query: 298 PDKR 301
           P KR
Sbjct: 899 PKKR 910
>04138
          Length = 800

 Score = 46.6 bits (109), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 32/99 (32%), Positives = 49/99 (49%), Gaps = 2/99 (2%)
 Frame = +1

Query: 160 EAVARLHQCKTPIIHRDLKVENILLHDRGHYVLCDFGSATNKFQNPQAEGVNAVE--DEI 217
           E +  +H+ K  I+HRD+K  NIL+  +G   L DFG A       +A  VN  +     
Sbjct: 46  ERLYYIHRNK--ILHRDMKAANILITKQGVLKLADFGLA-------RAFSVNLRQPNRYT 198

Query: 218 KKYTTLSYRAPEMVNLYSGKIITTKADIWALGCLLYKLC 256
            +  TL YR PE+  L   +  +T  D W  GC++ ++ 
Sbjct: 199 NRVVTLWYRPPEL--LLGDRNYSTAIDQWGAGCIMAEMW 309
>03240
          Length = 1683

 Score = 46.2 bits (108), Expect = 6e-05,   Method: Compositional matrix adjust.
 Identities = 58/258 (22%), Positives = 109/258 (42%), Gaps = 54/258 (20%)
 Frame = -3

Query: 122  VLILMDFCRGGQVVNLMNQRLQTGFTENEVLQIF-CDTCEAVARLHQCKTPIIHRDLKVE 180
            +  +MD+  GG ++ L+   ++    +  + + +  +  +A+  +H  +   IHRD+K +
Sbjct: 1066 LYFVMDYVPGGDLMGLL---IRMEILDEPLARFYVAELVQAIESVH--RMGFIHRDIKPD 902

Query: 181  NILLHDRGHYVLCDFG-----SATNKFQNPQAEGVNAVEDEIKKYTTL------------ 223
            NIL+   GH  L DFG       T+  +  Q +G +A +D ++    L            
Sbjct: 901  NILIDRNGHIKLTDFGLCTGFRWTHNSKYYQRDGTHARQDSMEVKCQLDEQCQCEILKPL 722

Query: 224  -------------------SYRAPEMVNLYSGKIITTKADIWALGCLLYKLCYFTLPF-- 262
                               +Y APE+++   G   T+  D W++G +L+++     PF  
Sbjct: 721  ERRRKREQRCLAHSLVGTPNYIAPEVLSRLGG--YTSVCDWWSVGVILFEMLVGHPPFYA 548

Query: 263  ---GESQVAICDGS--FTIPDNSRYSQDMHCLIRYMLEPDPDK-----RPDIYQVSYFS- 311
                E+Q  + +      IP  S  SQ    LI  +     D+       +I    +F+ 
Sbjct: 547  NTPAETQYKVINWKDMLKIPRESNLSQPAKDLILRLCCGSDDRLGLNGAGEIKTHMFFAG 368

Query: 312  --FKLLKKECP--VPNVQ 325
              F+ L+K+ P  VPN++
Sbjct: 367  VNFETLRKQQPPYVPNIR 314
>18484
          Length = 635

 Score = 45.4 bits (106), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 42/135 (31%), Positives = 64/135 (47%), Gaps = 5/135 (3%)
 Frame = +1

Query: 172 IIHRDLKVENILLHDRGHYVLCDFGSATNKFQNPQAEGVNAVEDEIKKYTTLSYRAPEMV 231
           II+RDLK++N++L   GH  + DFG           EG+           T  Y APE+V
Sbjct: 106 IIYRDLKLDNVMLDSEGHIKIADFGMCK--------EGMTGDATTRTFCGTPDYIAPEIV 261

Query: 232 NLYSGKIITTKADIWALGCLLYKLCYFTLPF-GESQ----VAICDGSFTIPDNSRYSQDM 286
            LY  +  +   D WA G LL+++     PF GE +     +I D + + P     S++ 
Sbjct: 262 -LY--QPYSKSVDWWAYGVLLFEMLAGQPPFDGEDEDELFSSITDHNVSYP--KAMSREA 426

Query: 287 HCLIRYMLEPDPDKR 301
             L + +L  +P KR
Sbjct: 427 VSLCKGLLMKNPTKR 471
>09606
          Length = 1300

 Score = 45.4 bits (106), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 44/193 (22%), Positives = 87/193 (45%), Gaps = 19/193 (9%)
 Frame = -3

Query: 82   HDLQVCKR-----EIQIMRDLSGHKNIVGYIDSSINNVSSGDVWEVLILMDFCRGGQVVN 136
            H ++ CKR      +++  D+S H N+V + +      +S  +W   ++++ C GG + +
Sbjct: 1022 HCIEKCKRPEVTNTVRMTHDIS-HPNVVQFHEWY---ETSNHLW---LVVELCTGGSLAD 864

Query: 137  LMNQRLQTGFTENEVLQIFCDTCEAVARLHQCKTPIIHRDLKVENILLHDRGHYVLCDFG 196
            ++ Q       E  +          +  +H     I+  DL+   +LL   G     DFG
Sbjct: 863  ILAQDHH--LPETSIRDFGIHLVTGLHYIHSLG--ILFHDLRPSKVLLDTSGVLKFADFG 696

Query: 197  SATNKFQNPQ------AEG-----VNAVEDEIKKYTTL---SYRAPEMVNLYSGKIITTK 242
             +  + +N +      AE      + + E+ +K+  T    +Y APE+   + G   +  
Sbjct: 695  LSKVEGENLEELFFKFAEAGDQWNIQSAEEMMKQVPTSGSPTYMAPEV---FQGAEPSIM 525

Query: 243  ADIWALGCLLYKL 255
            +D+WALGC+ Y++
Sbjct: 524  SDLWALGCVFYEM 486
>04591
          Length = 1117

 Score = 45.4 bits (106), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 39/169 (23%), Positives = 77/169 (45%), Gaps = 2/169 (1%)
 Frame = -2

Query: 89   REIQIMRDLSGHKNIVGYIDSSINNVSSGDVWE--VLILMDFCRGGQVVNLMNQRLQTGF 146
            REI+I++ L  H+N+V   +         + ++    ++ ++C    +  L+N  L+  F
Sbjct: 1074 REIKILQQLE-HENVVQLQEICHTQAGPYNRYKSTFYLIFEYC-DYDLAGLLNN-LRVKF 904

Query: 147  TENEVLQIFCDTCEAVARLHQCKTPIIHRDLKVENILLHDRGHYVLCDFGSATNKFQNPQ 206
            +  +   +       +  +H  +  I+HRD+K  NILL   G   L DFG +    ++ +
Sbjct: 903  SLADKKNLMSQLLNGLFYIHTKQ--ILHRDIKAANILLTRDGVLKLADFGLSRPWVKSKR 730

Query: 207  AEGVNAVEDEIKKYTTLSYRAPEMVNLYSGKIITTKADIWALGCLLYKL 255
                        +  TL YR PE+  L   +    + D+W +GC++ ++
Sbjct: 729  L---------TNRVVTLWYRPPEL--LLGEREYGPEIDMWGVGCIMAEM 616
>09007
          Length = 1440

 Score = 45.1 bits (105), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 64/291 (21%), Positives = 118/291 (40%), Gaps = 24/291 (8%)
 Frame = -1

Query: 41  IGRQQVTVDEVLAEGGFALV----FLVRTSNGVKCALKRMFVNNEH-DLQVCKREIQIMR 95
           I +  V + + L +G F  V    +   +   V+ A+K +  +  H D Q   +E  IM+
Sbjct: 888 ISKDCVALSKSLGQGHFGTVRQAIWTAESGEKVQVAVKCLSKDKIHKDGQEFLKETAIMQ 709

Query: 96  DLSGHKNIVGYIDSSINNVSSGDVWEVLILMDFCRGGQVVNLMNQRLQTGFTENEVLQIF 155
            L  H+NIV      ++N    D+  V  L       + V  ++ R+   F+   +    
Sbjct: 708 MLD-HENIVRVYGVVMDN--GADIMLVTELAPMRSLLECVKEVSARVD--FSVPRLCDFS 544

Query: 156 CDTCEAVARLHQCKTPIIHRDLKVENILLHDRGHYVLCD------FGSATNKFQNPQAEG 209
              C+ ++ L   +  ++HRDL   NILL  +    + D       G+    +Q+ Q   
Sbjct: 543 QQVCDGMSYLESKR--LVHRDLAARNILLFSKSKVKISDVGVSGALGAGKEYYQSQQT-- 376

Query: 210 VNAVEDEIKKYTTLSYRAPEMVNLYSGKIITTKADIWALGCLLYKLCYFTLPF------- 262
                  I     +++ APE    +     ++ +D+WA G LL++  +FT  F       
Sbjct: 375 -------IHLQNAVAWCAPES---FRNLCFSSASDVWAFGVLLWE--FFTHGFQPWAGLN 232

Query: 263 GESQVAICDGSFTIPDNSRYSQ------DMHCLIRYMLEPDPDKRPDIYQV 307
           G+  +   D     P + R  Q      + + ++    E +P +RP   Q+
Sbjct: 231 GQQIMEAVDA----PQSQRLEQPDLCPKEYYAVMLKCWEQEPQRRPTFSQL 91
>14116
          Length = 1017

 Score = 45.1 bits (105), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 54/222 (24%), Positives = 95/222 (42%), Gaps = 7/222 (3%)
 Frame = -1

Query: 41  IGRQQVTVDEVLAEGGFALV---FLV--RTSNGVKCALKRMFVNN--EHDLQVCKREIQI 93
           I R+ +T+ E + +G F  V   FL        +  A+K +  NN  E +LQ   +E  I
Sbjct: 645 IDREFLTMGEEIGKGNFGCVKRGFLTLPEQKGDILVAVKTLHNNNPREIELQSFLQEALI 466

Query: 94  MRDLSGHKNIVGYIDSSINNVSSGDVWEVLILMDFCRGGQVVNLMNQRLQTGFTENEVLQ 153
           M+D   H N++  I   +N          L+++ F + G ++  +    Q   T  +++ 
Sbjct: 465 MKDFH-HSNVLTLIGICLNLDDMP-----LVVLPFMKHGDLLTYIRDD-QHQPTIKDLIM 307

Query: 154 IFCDTCEAVARLHQCKTPIIHRDLKVENILLHDRGHYVLCDFGSATNKFQNPQAEGVNAV 213
              D    +  L   K   +HRDL   N +L +  H  + DFG A + ++       N  
Sbjct: 306 YGVDIARGMDYLAGLK--FVHRDLAARNCMLDEDFHVKVADFGLARDIYEKEYYSSEN-- 139

Query: 214 EDEIKKYTTLSYRAPEMVNLYSGKIITTKADIWALGCLLYKL 255
                K   L  +   + +L  G    +K D+W+ G +L++L
Sbjct: 138 -----KKAKLPVKWMALESLEKGN-YDSKTDVWSYGVVLWEL 31
>04852
          Length = 1462

 Score = 44.7 bits (104), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 35/142 (24%), Positives = 66/142 (46%), Gaps = 7/142 (4%)
 Frame = +1

Query: 173 IHRDLKVENILLHDRGHYVLCDFG-SATNKFQNPQAEGVNAVEDEIKKYTTLSYRAPEMV 231
           IHRDL   N+L+ +     + DFG S T  +   ++ G   V+          + APE  
Sbjct: 391 IHRDLAARNVLVTEEHVLKIADFGLSRTGDYYKKRSGGRLPVK----------WMAPEA- 537

Query: 232 NLYSGKIITTKADIWALGCLLYKLC------YFTLPFGESQVAICDGSFTIPDNSRYSQD 285
            L+  +  TTK+D+W+ G +L+++       Y ++P  E    + D ++ +P     S +
Sbjct: 538 -LFDMR-YTTKSDVWSFGVVLWEIFSLGGMPYASIPNEELYSKLLDDAYRMPRPELASGN 711

Query: 286 MHCLIRYMLEPDPDKRPDIYQV 307
           ++ ++       P  RP+  Q+
Sbjct: 712 LYAIMERCWLNRPSDRPEFSQL 777
>30755
          Length = 1137

 Score = 44.3 bits (103), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 37/129 (28%), Positives = 55/129 (42%), Gaps = 2/129 (1%)
 Frame = +2

Query: 136 NLMNQRLQTGFTENEVLQIFCDTCEAVARLHQCKTPIIHRDLKVENILLHDRGHYVLCDF 195
           +L ++R+   FTE        +   A+  LH     II+RDLK+EN+LL   GH  + DF
Sbjct: 2   HLSHERI---FTEERTRFYGAEIISALGYLHS--QGIIYRDLKLENLLLDKDGHIKVADF 166

Query: 196 GSATNKFQNPQAEGVNAVEDEIKKYTTLSYRAPEMV--NLYSGKIITTKADIWALGCLLY 253
           G         +               T  Y APE++  N Y   +     D W  G ++Y
Sbjct: 167 GLCKEDITYGRTTKTFC--------GTPEYLAPEVLDDNDYGRAV-----DWWGTGVVMY 307

Query: 254 KLCYFTLPF 262
           ++    LPF
Sbjct: 308 EMICGRLPF 334
>26711
          Length = 405

 Score = 43.9 bits (102), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 41/124 (33%), Positives = 58/124 (46%), Gaps = 10/124 (8%)
 Frame = -2

Query: 172 IIHRDLKVENILLH-DRGHYV-LCDFGSATNKFQNPQAEGVNAVEDEIKKYTTLSYRAPE 229
           ++H DLK  N+LL  D+   V L DFG A  K   PQ   +N        + T  + +PE
Sbjct: 353 VVHMDLKPSNLLLSGDKLDSVQLIDFGLA-RKLYPPQETFLN--------HGTPGFTSPE 201

Query: 230 MVNLYSGKIITTKADIWALGCLLYKLCYFTLPFGES-------QVAICDGSFTI-PDNSR 281
            +++   K I+T +D+W +G L Y L     PF          +   CD SF + P  S 
Sbjct: 200 ALDV---KPISTASDVWGVGVLAYILLSGQSPFQADSATESLKKTQTCDWSFDVCPSFSN 30

Query: 282 YSQD 285
            SQD
Sbjct: 29  MSQD 18
>01392
          Length = 1806

 Score = 42.7 bits (99), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 46/163 (28%), Positives = 68/163 (41%), Gaps = 33/163 (20%)
 Frame = -1

Query: 172  IIHRDLKVENILLHDRGHYV---LCDFGSATNKFQNPQAEGVNAVEDEIKKYTTLS---- 224
            I HRDLK ENIL       V   +CDF  A+         G++   D  K    L+    
Sbjct: 1728 IAHRDLKPENILCEHLDDVVPVKICDFDLAS---------GISCDGDGTKTPELLTPVGS 1576

Query: 225  --YRAPEMVNLYSGKIIT--TKADIWALGCLLYKLCYFTLPF--------GESQVAIC-- 270
              Y APE+V+ + G   +   + D+W+LG +LY +     PF        G ++   C  
Sbjct: 1575 AEYMAPEVVDAWVGDSFSYDKRCDLWSLGIILYIMLCGYPPFYGQCGEDCGWNRGEACHD 1396

Query: 271  ----------DGSFTIP--DNSRYSQDMHCLIRYMLEPDPDKR 301
                      DG +  P  + +  S     LIR++L  +P KR
Sbjct: 1395 CQDMLFNSIQDGHYKFPSQEWTSISSSAKDLIRHLLVREPRKR 1267
>07291
          Length = 833

 Score = 42.7 bits (99), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 25/97 (25%), Positives = 50/97 (51%)
 Frame = +1

Query: 159 CEAVARLHQCKTPIIHRDLKVENILLHDRGHYVLCDFGSATNKFQNPQAEGVNAVEDEIK 218
            + +A L + K  ++HR+L   N ++ + G   L D+G   + F  PQ+       D+  
Sbjct: 79  ADGMAYLQEVK--VVHRNLAARNCIVTEDGRLQLSDYGVTGSLF--PQS---YYTADDSP 237

Query: 219 KYTTLSYRAPEMVNLYSGKIITTKADIWALGCLLYKL 255
               + + APE ++ +     ++K+D+WA G +L++L
Sbjct: 238 ARDLVKWMAPETIDNFH---FSSKSDVWAFGVVLWEL 339
>12786
          Length = 460

 Score = 42.4 bits (98), Expect = 9e-04,   Method: Compositional matrix adjust.
 Identities = 39/139 (28%), Positives = 61/139 (43%), Gaps = 17/139 (12%)
 Frame = -3

Query: 141 RLQTGFTENEVLQIFCDTCEAVARLHQCKTPIIHRDLKVENILLHDRGHYVLCDFGSATN 200
           R+   F   E+L+       AV  LH     +IH DLK  N +L   G+  L DFG A  
Sbjct: 413 RMMIKFYWREMLR-------AVKALHN--EGVIHSDLKPANFMLV-AGNLKLIDFGIANT 264

Query: 201 KFQNPQAEGVNAVEDEIKKYTTLSYRAPEMV--------------NLYSGK---IITTKA 243
                Q +  + ++D   +  T SY +PE +              + +  K    +  ++
Sbjct: 263 ----LQQDKTSVLKDS--RVGTPSYMSPEAIMAACDDSADDSMEEDGHRTKPKYKVGVRS 102

Query: 244 DIWALGCLLYKLCYFTLPF 262
           D+W+LGC+LY + Y   PF
Sbjct: 101 DVWSLGCILYNMVYGRTPF 45
>13066
          Length = 551

 Score = 42.0 bits (97), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 39/134 (29%), Positives = 56/134 (41%), Gaps = 7/134 (5%)
 Frame = +3

Query: 123 LILMDFCRGGQVVNLMNQRLQTGFTENEVLQI-FCDTCEAVARLHQCKTPIIHRDLKVEN 181
            I M F   G ++  + +    GF + +  +I F     A+  LH     + HRDLK EN
Sbjct: 204 FIFMRFAERGDLLTYIQE---VGFVKEKQAKIWFYQMTTALNYLHS--YDVAHRDLKCEN 368

Query: 182 ILLHDRGHYVLCDFGSATNKFQNPQAEGVNAVEDEIKKYT------TLSYRAPEMVNLYS 235
           ILL    +  L DFG A              + +  +KY       + +Y APE+V  Y 
Sbjct: 369 ILLSSHFNVKLADFGFAC-----------ACITESGEKYMSRTYCGSAAYAAPEIV--YG 509

Query: 236 GKIITTKADIWALG 249
                  AD W+LG
Sbjct: 510 APYAPKVADAWSLG 551
>07836
          Length = 1478

 Score = 41.6 bits (96), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 43/173 (24%), Positives = 79/173 (45%), Gaps = 14/173 (8%)
 Frame = -1

Query: 97   LSGHKNIVGYIDSSINNVSSGDVWEVLILM-DFCRGGQVVNLMNQRLQTGFTENEVLQIF 155
            L  H+NI+G+I + I    S   W  L L+ D+   G + + +  R+      +E+L + 
Sbjct: 1397 LLRHENILGFIAADIKGTGS---WTQLFLITDYHENGSLHDYLLSRV---LDSSEMLALA 1236

Query: 156  CDTCEAVARLH------QCKTPIIHRDLKVENILLHDRGHYVLCDFGSATNKFQNPQAEG 209
                  +A LH      + K  I HRD+K +NIL+   G   + D G A       ++  
Sbjct: 1235 HSAICGLAHLHIEIFGTRGKPAIAHRDIKSKNILVKKNGTCCIADLGLAVRYIS--ESNE 1062

Query: 210  VNAVEDEIKKYTTLSYRAPEMVNLYSGKIITTK-------ADIWALGCLLYKL 255
            V+   +   +  T  Y APE++ +    ++  K       AD++A G +++++
Sbjct: 1061 VDVAPN--PRQGTKRYMAPEVLEM----LLNVKNFDAFKQADMYAFGLVMWEI 921
>01718
          Length = 959

 Score = 40.8 bits (94), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 49/212 (23%), Positives = 96/212 (45%), Gaps = 6/212 (2%)
 Frame = +3

Query: 50  EVLAEGGFALVFLV--RTSNGVKCALKRMFVNNEHDLQVCKREIQIMRDLSGHKNIVGYI 107
           E +  G F+ VF V  R +  V         +N H++    RE+Q++  L  H NI+ ++
Sbjct: 165 EKIGAGFFSEVFKVTHRITGQVMALKMNTMTSNRHNML---REVQLLNRLQ-HANILRFM 332

Query: 108 DSSINNVSSGDVWEVLILMDFCRGGQVVNLMNQRLQTGFTENEVLQIFCDTCEAVARLHQ 167
              ++        ++  L ++   G +  L+ ++        + +Q+       +  LH 
Sbjct: 333 GVCVHE------GQLHALTEYIPSGNLEQLLEKK-DEELPWTQRIQLTLGLARGLDYLH- 488

Query: 168 CKTPIIHRDLKVENILLHDRG----HYVLCDFGSATNKFQNPQAEGVNAVEDEIKKYTTL 223
             T  IHRDL  +NIL+        H V+ DFG AT K  +P        ++++    + 
Sbjct: 489 -STRFIHRDLTSKNILIRREDNHGYHAVIADFGLAT-KIPDPLD------KEKLPTVGSP 644

Query: 224 SYRAPEMVNLYSGKIITTKADIWALGCLLYKL 255
            + APE++N   G     +AD++++G ++ ++
Sbjct: 645 YWMAPEVLN---GHFYNERADLFSVGIIMCEI 731
>37602
          Length = 804

 Score = 38.9 bits (89), Expect = 0.009,   Method: Composition-based stats.
 Identities = 28/95 (29%), Positives = 48/95 (50%)
 Frame = -1

Query: 101 KNIVGYIDSSINNVSSGDVWEVLILMDFCRGGQVVNLMNQRLQTGFTENEVLQIFCDTCE 160
           +  VGY DS +       +W   I M++C GG + ++ +  +    TE ++  +  +T +
Sbjct: 339 QTFVGYFDSYLRREK---LW---IAMEYCGGGSMQDIYH--VTGPLTEPQIAFVCRETLK 184

Query: 161 AVARLHQCKTPIIHRDLKVENILLHDRGHYVLCDF 195
            +  LH  +   +HRD+K  NILL + G   L DF
Sbjct: 183 GLHYLH--RRGKMHRDIKGANILLTEEGDVKLADF 85
>28157
          Length = 400

 Score = 38.9 bits (89), Expect = 0.010,   Method: Composition-based stats.
 Identities = 36/132 (27%), Positives = 65/132 (49%), Gaps = 3/132 (2%)
 Frame = +3

Query: 72  ALKRMFVNNEHDLQVCKREIQIMRDLSGHKNIVGYIDSSINNVSSGDVWEVLILMDFCRG 131
           A+KR  + +E + +   +E++ +  +S H NIV    +  ++        V ++M++  G
Sbjct: 12  AVKR--IESEQEKKSFMQELKQLSRVS-HPNIVCLYGACRDH-------PVCLVMEYAEG 161

Query: 132 GQVVNLMN-QRLQTGFTENEVLQIFCDTCEAVARLHQCK-TPIIHRDLKVENILLHDRGH 189
           G + N+++    Q  +T    +         V  LH  K   +IHRDLK  N+LL   G 
Sbjct: 162 GSLYNVLHGSGPQPQYTAAHAMNWLLQCALGVEYLHGMKPKALIHRDLKPPNLLLIQCGT 341

Query: 190 YV-LCDFGSATN 200
            + +CDFG+A +
Sbjct: 342 KLKICDFGTACD 377
>21808
          Length = 1011

 Score = 38.9 bits (89), Expect = 0.010,   Method: Compositional matrix adjust.
 Identities = 27/91 (29%), Positives = 41/91 (45%), Gaps = 1/91 (1%)
 Frame = +1

Query: 173 IHRDLKVENILLHDRGHYVLCDFGSATNKFQNPQAEGVNAVEDEIKKYTTLSYRAPEMVN 232
           IHRDL   NIL+ D     + DFG A       +    +  E  +     + + APE  N
Sbjct: 301 IHRDLAARNILVSDNNTVKIADFGLA-------RVIKEDEYEARVGARFPIKWTAPEAAN 459

Query: 233 LYSGKIITTKADIWALGCLLYK-LCYFTLPF 262
                  T K+D+W+ G LL + + Y  +P+
Sbjct: 460 YNR---FTIKSDVWSFGILLTETVTYGRVPY 543
>00392
          Length = 668

 Score = 38.5 bits (88), Expect = 0.014,   Method: Compositional matrix adjust.
 Identities = 48/201 (23%), Positives = 84/201 (41%), Gaps = 12/201 (5%)
 Frame = +3

Query: 80  NEHDLQVCKREIQIMRDLSGHKNIVGYIDSSINNVSSGDVWEVLILMDFCRGGQVVNLMN 139
           N+ + Q  K E +++++L  H NIV + D           WE        R  +V+ L+ 
Sbjct: 51  NKAERQRFKEEAEMLKELQ-HPNIVRFFD----------YWE----EHNHRNRKVIILVT 185

Query: 140 QRLQTGFTENEV-------LQIFCDTCEAVAR----LHQCKTPIIHRDLKVENILLHD-R 187
           + + +G  +  +       ++I  + C  V +    LH    P+IHRDLK +NI +    
Sbjct: 186 ELMTSGTLKTYLKRFKKPNVKILKNWCRQVLKGLYFLHTRTPPVIHRDLKCDNIFITGPT 365

Query: 188 GHYVLCDFGSATNKFQNPQAEGVNAVEDEIKKYTTLSYRAPEMVNLYSGKIITTKADIWA 247
           G   + D G AT K Q+     +   E          + APEM   +  + +    D++A
Sbjct: 366 GSVKIGDLGLATLKNQSFAKSVIGTPE----------FMAPEMYEEHYDEAV----DVYA 503

Query: 248 LGCLLYKLCYFTLPFGESQVA 268
            G  + ++     P+ E   A
Sbjct: 504 FGMCMLEMASSEYPYSECSNA 566
>21079
          Length = 878

 Score = 38.5 bits (88), Expect = 0.015,   Method: Compositional matrix adjust.
 Identities = 39/138 (28%), Positives = 68/138 (49%), Gaps = 4/138 (2%)
 Frame = +1

Query: 122 VLILMDFCRGGQVVNLMNQRLQTGF--TENEVLQIFCDTCEAVARLHQCKTPIIHRDLKV 179
           ++++M+F   G+   L  + ++  F  TE + +      C  V  +H     I+H DLK 
Sbjct: 49  MVLVMEFVGAGE---LFERVIRDDFVLTERDCVHFVRQICSGVGYMH--TQSILHLDLKP 213

Query: 180 ENIL-LHDRGHYV-LCDFGSATNKFQNPQAEGVNAVEDEIKKYTTLSYRAPEMVNLYSGK 237
           EN+L + D  + + + DFG A  +F  P  + +  +      + T  + APE+VN Y   
Sbjct: 214 ENVLCVSDNSNQIKIIDFGLA--RFYKP-GDSLQVL------FGTPEFIAPEVVN-YDEI 363

Query: 238 IITTKADIWALGCLLYKL 255
             TT  D+W++G + Y L
Sbjct: 364 NFTT--DMWSIGVICYIL 411
>28638
          Length = 1458

 Score = 38.1 bits (87), Expect = 0.015,   Method: Compositional matrix adjust.
 Identities = 33/100 (33%), Positives = 48/100 (48%), Gaps = 3/100 (3%)
 Frame = -1

Query: 159 CEAVARLHQCKTPIIHRDLKVENILLHD--RGHYVLCDFGSATNKFQNPQAEGVNAVEDE 216
           C A+  L   +  IIH DLK ENILL +  R    + DFGS+    Q             
Sbjct: 807 CTALLFLATPEMNIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQ------------R 664

Query: 217 IKKYT-TLSYRAPEMVNLYSGKIITTKADIWALGCLLYKL 255
           I +Y  +  YR+PE++    G       D+W+LGC+L ++
Sbjct: 663 IYQYIQSRFYRSPEVL---LGVPYDLAIDMWSLGCILVEM 553
>11185
          Length = 473

 Score = 37.7 bits (86), Expect = 0.023,   Method: Composition-based stats.
 Identities = 27/98 (27%), Positives = 48/98 (48%), Gaps = 14/98 (14%)
 Frame = +1

Query: 172 IIHRDLKVENILLHDRGHYVLCDFGSATNKFQNPQ------AEG-----VNAVEDEIKKY 220
           I+  DL+   +LL   G     DFG +  + +N +      AE      + + E+ +K+ 
Sbjct: 64  ILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEAGDQWNIQSAEEMMKQV 243

Query: 221 TTL---SYRAPEMVNLYSGKIITTKADIWALGCLLYKL 255
            T    +Y APE   ++ G   +  +D+WALGC+ Y++
Sbjct: 244 PTSGSPTYMAPE---VFQGAEPSIMSDLWALGCVFYEM 348
>38560
          Length = 479

 Score = 37.4 bits (85), Expect = 0.031,   Method: Composition-based stats.
 Identities = 28/90 (31%), Positives = 47/90 (52%), Gaps = 6/90 (6%)
 Frame = -3

Query: 224 SYRAPEMVNLYSG-KIITTKADIWALGCLLYKLCYFTLPFGESQVAIC-----DGSFTIP 277
           +Y APE++   SG + + ++ADIW++G LLY L    LPF + + +            +P
Sbjct: 390 AYAAPELI---SGLEYLGSEADIWSMGVLLYALLCGYLPFDDEKXSHL*QKNQKRKDEVP 220

Query: 278 DNSRYSQDMHCLIRYMLEPDPDKRPDIYQV 307
           +    S+D   L+  ML+ DP  R  I ++
Sbjct: 219 E--WLSEDTTKLLEGMLQTDPSHRITIRRL 136
>07940
          Length = 1336

 Score = 37.0 bits (84), Expect = 0.036,   Method: Compositional matrix adjust.
 Identities = 32/98 (32%), Positives = 47/98 (47%), Gaps = 4/98 (4%)
 Frame = -3

Query: 167 QCKTPIIHRDLKVENILLHDRGHYVLCDFGSATNKFQNPQAEGVNAVEDEIKKYTT---- 222
           QC    IHRDL   N+L+ +     + DFG   N  Q           D  +K T     
Sbjct: 287 QC----IHRDLAARNVLVAEEYVLKIADFGLTRNLQQF----------DYYRKTTDGRLP 150

Query: 223 LSYRAPEMVNLYSGKIITTKADIWALGCLLYKLCYFTL 260
           + + APE   L+  K  T+K+D+W+ G LL+++  FTL
Sbjct: 149 VKWMAPEA--LFDRK-YTSKSDVWSYGVLLWEI--FTL 51
>27546
          Length = 426

 Score = 36.6 bits (83), Expect = 0.044,   Method: Composition-based stats.
 Identities = 35/111 (31%), Positives = 53/111 (47%), Gaps = 1/111 (0%)
 Frame = -1

Query: 89  REIQIMRDLSGHKNIVGYIDSSINNVSSGDVWEVLILMDFCRGGQVVNLMNQRLQTG-FT 147
           RE++I+  L  H NI+  I S +         ++ I M +   G   ++++   +TG   
Sbjct: 333 RELEILTRLD-HPNII-QIHSILQRGP-----KIFIFMRYAEKG---DMLSHIKKTGPID 184

Query: 148 ENEVLQIFCDTCEAVARLHQCKTPIIHRDLKVENILLHDRGHYVLCDFGSA 198
           E +    F    +A+  LH     I HRDLK ENILL  R +  + DFG A
Sbjct: 183 EAQTKVWFFQMAKALQYLHS--HDIAHRDLKCENILLSKRLNVKIADFGFA 37
>20655
          Length = 1181

 Score = 36.6 bits (83), Expect = 0.052,   Method: Compositional matrix adjust.
 Identities = 20/34 (58%), Positives = 22/34 (64%)
 Frame = +2

Query: 274 FTIPDNSRYSQDMHCLIRYMLEPDPDKRPDIYQV 307
           F  P+ SR SQD   LIR ML  DPDKR +I QV
Sbjct: 35  FPKPEWSRVSQDAKDLIRGMLCTDPDKRLNIKQV 136
>17975
          Length = 449

 Score = 36.6 bits (83), Expect = 0.052,   Method: Composition-based stats.
 Identities = 44/158 (27%), Positives = 72/158 (45%), Gaps = 11/158 (6%)
 Frame = +3

Query: 57  FALVFLVR-TSNGVKCALKRM------FVNNEHDLQVCKREIQIMRDLSGHKNIV---GY 106
           FA+V L R    G K A+K +       V+  H  Q    E++ M+ L  H N+V     
Sbjct: 6   FAVVKLARHVFTGEKVAVKVIDKTKLDEVSRSHLFQ----EVRCMK-LVQHPNVVRLYEV 170

Query: 107 IDSSINNVSSGDVWEVLILMDFCRGGQVVNLMNQRLQTGFTENEVLQIFCDTCEAVARLH 166
           ID+           ++ ++++   GG + + +  R   G  E    + F    EA++  H
Sbjct: 171 IDTQT---------KLYLILELGDGGDMYDYI-MRHSGGLEEKLAKRYFRQIVEAISYCH 320

Query: 167 QCKTPIIHRDLKVENILLHDR-GHYVLCDFGSATNKFQ 203
             K  ++HRDLK EN++  ++ G   L DFG +T   Q
Sbjct: 321 --KLHVVHRDLKPENVVFFEKPGLVKLTDFGFSTCLLQ 428
>27405
          Length = 532

 Score = 36.6 bits (83), Expect = 0.054,   Method: Composition-based stats.
 Identities = 34/125 (27%), Positives = 54/125 (43%), Gaps = 1/125 (0%)
 Frame = -3

Query: 121 EVLILMDFCRGGQVVNLMNQRLQTGFTENEVLQIFCDTCEAVARLHQCKTPIIHRDLKVE 180
           ++  ++D   GG +   ++Q     FTE EV     +    +  +H     +++RDLK  
Sbjct: 332 KLCFILDLMNGGDLHYHLSQ--HGVFTEKEVRFYAAEVMLGLEHMHS--RFVVYRDLKPA 165

Query: 181 NILLHDRGHYVLCDFGSATN-KFQNPQAEGVNAVEDEIKKYTTLSYRAPEMVNLYSGKII 239
           NILL + GH  + D G A +   + P A              T  Y APE+  L  G+  
Sbjct: 164 NILLDENGHVRISDLGLACDFSKKKPHAS-----------VGTHGYMAPEV--LMKGQAY 24

Query: 240 TTKAD 244
            + AD
Sbjct: 23  DSSAD 9
>12672
          Length = 773

 Score = 36.6 bits (83), Expect = 0.054,   Method: Compositional matrix adjust.
 Identities = 40/155 (25%), Positives = 69/155 (44%), Gaps = 1/155 (0%)
 Frame = +3

Query: 173 IHRDLKVENILLHDRGHYVLCDFGSATNKFQNPQAEGVNAVEDEIKKYTTLSYRAPEMVN 232
           +HRD+K  NILL       + DF +  +    P  EG   V++      T +Y APE ++
Sbjct: 57  VHRDIKTANILLDSEYTAKVGDFATVVSA---PSGEG-KTVQNASVVIGTAAYLAPEAIH 224

Query: 233 LYSGKIITTKADIWALGCLLYKLCYFTLPFGESQVAICDGSFTIPDNSRYSQDMHCLIRY 292
                 ++TK D ++ G +L ++    +    S+      S  I +N    +++H  +  
Sbjct: 225 F----DVSTKLDSYSFGVVLLEVITGLVAQDYSREERTLSSH-IMENVEEPEEIHDFVDQ 389

Query: 293 MLEPDPDKRPD-IYQVSYFSFKLLKKECPVPNVQN 326
                PD   D +Y +S     L KK+   PNV++
Sbjct: 390 SAGTWPDGAVDKLYDISMRCLNLSKKQR--PNVKD 488
>07833
          Length = 1504

 Score = 36.2 bits (82), Expect = 0.057,   Method: Compositional matrix adjust.
 Identities = 42/188 (22%), Positives = 77/188 (40%), Gaps = 7/188 (3%)
 Frame = -3

Query: 122  VLILMDFCRGGQVVNLMNQRLQTGFTENEVLQIFCDTCEAVARLHQCKTPIIHRDLKVEN 181
            ++++  F   G + N ++        +N+ L+   D    +  LH  +  I        N
Sbjct: 1394 LVLISQFMPFGSLYNTLHGESGIVVDQNQSLRFAMDIARGMEFLHSMEPTI-------PN 1236

Query: 182  ILLHDRGHYVLCDFGSATNKFQNPQAEGVNAVEDEIKKYTTLSYRAPEMVNLYSGKIITT 241
             LL  +   +  D  +  N      A+   +  ++ K Y+  ++ APE +      I T 
Sbjct: 1235 FLLTSKHVMIDEDLTARIN-----MADYCFSFHEKGKVYSP-AWMAPEALQRRPDDINTR 1074

Query: 242  KADIWALGCLLYKLCYFTLPFGE-------SQVAICDGSFTIPDNSRYSQDMHCLIRYML 294
             AD+W+   L+++L    +PF E        +VA+     +IP     S  M  LI+  +
Sbjct: 1073 AADMWSFAILMWELETREVPFAELSSMEVGMKVALEGLRISIPPG--ISLHMSRLIKICM 900

Query: 295  EPDPDKRP 302
              +P KRP
Sbjct: 899  NEEPGKRP 876
>21433
          Length = 590

 Score = 36.2 bits (82), Expect = 0.071,   Method: Composition-based stats.
 Identities = 31/91 (34%), Positives = 42/91 (46%)
 Frame = +2

Query: 172 IIHRDLKVENILLHDRGHYVLCDFGSATNKFQNPQAEGVNAVEDEIKKYTTLSYRAPEMV 231
           +IHRD+K EN+LL  +G   + DFG + +    P +              TL Y  PEMV
Sbjct: 230 VIHRDIKPENLLLGLKGDLKIADFGWSVHA---PSSRRTTMC-------GTLDYLPPEMV 379

Query: 232 NLYSGKIITTKADIWALGCLLYKLCYFTLPF 262
               GK      D+W+LG L Y+    T P 
Sbjct: 380 ---EGKTHDENVDLWSLGVLCYEFLVGTPPL 463
>00715
          Length = 1788

 Score = 35.8 bits (81), Expect = 0.081,   Method: Compositional matrix adjust.
 Identities = 30/109 (27%), Positives = 51/109 (46%), Gaps = 18/109 (16%)
 Frame = +1

Query: 172 IIHRDLKVENILLHDRGHYVLCDFGS------------------ATNKFQNPQAEGVNAV 213
           I+H DLK  N LL       + DFG                   A N+ +    +G  A 
Sbjct: 301 IVHLDLKPANCLLTRDLKLRIADFGCCHQLTPTGLDMGEREGGMAGNELELTPVQG--AW 474

Query: 214 EDEIKKYTTLSYRAPEMVNLYSGKIITTKADIWALGCLLYKLCYFTLPF 262
           ++E+    TL+YRAPE++    G   + ++D+++LG  L+++C    P+
Sbjct: 475 KNELAG--TLAYRAPELLK---GLQPSVRSDVYSLGITLWQMCTRQGPY 606
>03508
          Length = 1463

 Score = 35.8 bits (81), Expect = 0.082,   Method: Compositional matrix adjust.
 Identities = 28/114 (24%), Positives = 54/114 (47%), Gaps = 1/114 (0%)
 Frame = +1

Query: 140 QRLQTGFTENEVLQIFCDTCEAVARLHQCKTPIIHRDLKVENILL-HDRGHYVLCDFGSA 198
           ++L   FT+ ++     +  +A+   H     I+HRD+K  N+++ H+     L D+G A
Sbjct: 844 KQLYQTFTDYDIRFYLYELMKALDFCHS--MGIMHRDVKPHNVMIDHENKKLRLIDWGLA 1017

Query: 199 TNKFQNPQAEGVNAVEDEIKKYTTLSYRAPEMVNLYSGKIITTKADIWALGCLL 252
             +F +P  E    V        +  ++ PE+  L   ++     D+W+LGC+ 
Sbjct: 1018--EFYHPGMEYNVRV-------ASRYFKGPEL--LLDYQMYDYSLDMWSLGCMF 1146
>18996
          Length = 491

 Score = 35.4 bits (80), Expect = 0.12,   Method: Compositional matrix adjust.
 Identities = 24/83 (28%), Positives = 40/83 (48%)
 Frame = +2

Query: 173 IHRDLKVENILLHDRGHYVLCDFGSATNKFQNPQAEGVNAVEDEIKKYTTLSYRAPEMVN 232
           IHRDL   NIL+ DR    + DFG A     +    G++  +  IK Y+      PE + 
Sbjct: 2   IHRDLAARNILV-DRSCVKISDFGLAQFANADGYYYGISQRDIPIKWYS------PEAIE 160

Query: 233 LYSGKIITTKADIWALGCLLYKL 255
                  ++ +D+W+ G  L+++
Sbjct: 161 TCK---FSSYSDVWSYGVTLFEM 220
>17300
          Length = 480

 Score = 33.1 bits (74), Expect = 0.62,   Method: Composition-based stats.
 Identities = 24/98 (24%), Positives = 49/98 (50%), Gaps = 6/98 (6%)
 Frame = +1

Query: 173 IHRDLKVENILLHDRGHYVLCDFGSATNKFQNPQAEGVNAVEDEIKKYTT------LSYR 226
           +HRDL   NIL+++     + DFG  + + ++   EG          YTT      + + 
Sbjct: 40  VHRDLAARNILVNEILVCKVADFG-LSREIESDTTEGA---------YTTKGGKIPVRWT 189

Query: 227 APEMVNLYSGKIITTKADIWALGCLLYKLCYFTLPFGE 264
           APE +   + +  T+ +D+W+ G +++++    + +GE
Sbjct: 190 APEAI---AYRKFTSASDVWSFGVVMWEV----MSYGE 282
>03106
          Length = 2384

 Score = 32.3 bits (72), Expect = 0.84,   Method: Composition-based stats.
 Identities = 19/63 (30%), Positives = 31/63 (49%), Gaps = 1/63 (1%)
 Frame = +2

Query: 241 TKADIWALGCLLYKLCYFTLPFGESQVAICDGSFTIPD-NSRYSQDMHCLIRYMLEPDPD 299
           +KAD+WA G + Y++   + PF     + C     +P       + +  L+  MLE DP 
Sbjct: 23  SKADVWAAGAVAYEIFGASNPFYSRLDSACYSQHDLPSLPGDTPEGVVRLVTSMLERDPA 202

Query: 300 KRP 302
           +RP
Sbjct: 203 QRP 211
>32000
          Length = 644

 Score = 32.3 bits (72), Expect = 0.94,   Method: Composition-based stats.
 Identities = 16/43 (37%), Positives = 25/43 (58%), Gaps = 4/43 (9%)
 Frame = -1

Query: 217 IKKYT----TLSYRAPEMVNLYSGKIITTKADIWALGCLLYKL 255
           ++ YT    TL YRAPE+  L   +  +   DIW+LGC+  ++
Sbjct: 527 VRTYTHEVITLWYRAPEI--LLGCRFYSVPVDIWSLGCIFVEM 405
>19301
          Length = 712

 Score = 32.0 bits (71), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 41/155 (26%), Positives = 66/155 (42%)
 Frame = +2

Query: 44  QQVTVDEVLAEGGFALVFLVRTSNGVKCALKRMFVNNEHDLQVCKREIQIMRDLSGHKNI 103
           + +T  E L  G    VFL     G  CA + + V    D++  + +I+ +R L+ H NI
Sbjct: 305 ESITDLEWLGSGAQGAVFL-----GKLCA-EEVAVKKVRDIK--ETDIRNLRKLN-HPNI 457

Query: 104 VGYIDSSINNVSSGDVWEVLILMDFCRGGQVVNLMNQRLQTGFTENEVLQIFCDTCEAVA 163
           + +                 I+M++C  GQ+  ++  R         VL         + 
Sbjct: 458 ISFKGVCTQAPC------YCIIMEYCPYGQLYEVL--RDGKEIPPALVLDWSKQIASGMN 613

Query: 164 RLHQCKTPIIHRDLKVENILLHDRGHYVLCDFGSA 198
            LH  K  IIHRDLK  N+L+       + DFG++
Sbjct: 614 YLHSHK--IIHRDLKSPNVLVAKNDVVKISDFGTS 712
>20152
          Length = 445

 Score = 31.2 bits (69), Expect = 2.1,   Method: Composition-based stats.
 Identities = 23/70 (32%), Positives = 33/70 (47%), Gaps = 6/70 (8%)
 Frame = +1

Query: 244 DIWALGCLLYKLCYFTLPFGESQ-----VAICDGSFTIPDN-SRYSQDMHCLIRYMLEPD 297
           D+W+LG +LY L     PF E+        I D  + IP + S   QD   LI  ML+ +
Sbjct: 43  DVWSLGVILYMLVVGEAPFQEANDSETLTMIMDCRYQIPPHISHKCQD---LIEKMLQRE 213

Query: 298 PDKRPDIYQV 307
           P  R  +  +
Sbjct: 214 PVDRASLPHI 243
>02638
          Length = 1490

 Score = 29.3 bits (64), Expect = 7.2,   Method: Composition-based stats.
 Identities = 21/89 (23%), Positives = 39/89 (43%), Gaps = 8/89 (8%)
 Frame = +1

Query: 222 TLSYRAPEMVNLYSGKIITTKADIWALGCLLYKLCYFTLPFGESQVA--------ICDGS 273
           T+++ APE++    G+      D+W++GC++ ++C    P+    ++        I    
Sbjct: 25  TIAFMAPEVLR---GESYGRACDVWSVGCVMIEMCTCRPPWNSHDISNHLALIFKIASSV 195

Query: 274 FTIPDNSRYSQDMHCLIRYMLEPDPDKRP 302
              P     S  +  L+   LE D D RP
Sbjct: 196 DPPPIPENMSPPVRDLMLRCLEQDSDFRP 282
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|153791474|ref|NP_473394.3| G protein-coupled receptor
98 [Mus musculus]
         (6298 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

17729                                                                  79   4e-14
19485                                                                  38   0.16 
32189                                                                  33   2.8  
13549                                                                  33   3.0  
>17729
          Length = 490

 Score = 79.3 bits (194), Expect = 4e-14,   Method: Compositional matrix adjust.
 Identities = 57/179 (31%), Positives = 91/179 (50%), Gaps = 2/179 (1%)
 Frame = -1

Query: 2045 FRANQTEATITISILDDAEPERSESVFIELFNSSLVDKVQNRPIPH-SPRLGPKVETVAH 2103
            F  N+T  +I I I+DD E E  E  F++L               H +P  G  +  +A 
Sbjct: 490  FEKNETLKSIFIEIVDDCEWEPDEFFFVKL---------------HVTPDDGVSLGNIAI 356

Query: 2104 LVI-VANDDAFGTVQLSATSVHVAENHVGPIINVTRTGGTFADVSVKFKAVPITAAAGED 2162
              I + NDD  G +  +  S  + E+ +  +I V+RTGG    VSVK++   ITA  G+D
Sbjct: 355  CQITIINDDEPGVLAFTKPSYVIKESGLRALIPVSRTGGADGHVSVKWRTKDITAINGKD 176

Query: 2163 YSIASSDVVLLEGETTKAVPIYIINDIYPELEETFLVQLLNETTGGATLGPLREAVITI 2221
            +     ++     ET+K++ I +      E +E+F ++L  E+ GGATLG L + ++TI
Sbjct: 175  FKGGEGELKFDNQETSKSIDIILFESNKEERDESFQIELF-ESDGGATLGKLTKCIVTI 2

 Score = 66.2 bits (160), Expect = 4e-10,   Method: Compositional matrix adjust.
 Identities = 46/160 (28%), Positives = 83/160 (51%), Gaps = 4/160 (2%)
 Frame = -1

Query: 2174 EGETTKAVPIYIINDIYPELEETFLVQLLNETTGGATLGPLREAVITIEASDDPYGLFGF 2233
            + ET K++ I I++D   E +E F V+L      G +LG +    ITI   D+P G+  F
Sbjct: 484  KNETLKSIFIEIVDDCEWEPDEFFFVKLHVTPDDGVSLGNIAICQITIINDDEP-GVLAF 308

Query: 2234 QNTKFIVEEPEFNSVRVNVPIIRNSGTLGNVTVQW----VAIINGQFATGDLRVVSGNVT 2289
                ++++E   + +R  +P+ R  G  G+V+V+W    +  ING+    D +   G + 
Sbjct: 307  TKPSYVIKE---SGLRALIPVSRTGGADGHVSVKWRTKDITAINGK----DFKGGEGELK 149

Query: 2290 FAPGETIQTLLLEVLADDVPEIEEVVQVQLAAASGGGTIG 2329
            F   ET +++ + +   +  E +E  Q++L  + GG T+G
Sbjct: 148  FDNQETSKSIDIILFESNKEERDESFQIELFESDGGATLG 29

 Score = 63.5 bits (153), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 52/174 (29%), Positives = 81/174 (46%), Gaps = 1/174 (0%)
 Frame = -1

Query: 3014 FTDGERFKHVDVMILDDDMPEGDERFQLLL-TNPSPGLELGKNTIALITVLANDDGPGVL 3072
            F   E  K + + I+DD   E DE F + L   P  G+ LG   I  IT++ NDD PGVL
Sbjct: 490  FEKNETLKSIFIEIVDDCEWEPDEFFFVKLHVTPDDGVSLGNIAICQITII-NDDEPGVL 314

Query: 3073 SFNNSGHIFLREPTSLYVQESVAVLVIVREPAQGLFGTVAVQFVVTEVNSSTESKDLSPS 3132
            +F    ++         ++ES    +I      G  G V+V++   ++ ++   KD    
Sbjct: 313  AFTKPSYV---------IKESGLRALIPVSRTGGADGHVSVKWRTKDI-TAINGKDFKGG 164

Query: 3133 KGFIVLEEGVRSKTLRISAILDTEPEMDEHFVCTLFNPTGGARLGAHVQTLITI 3186
            +G +  +    SK++ I      + E DE F   LF   GGA LG   + ++TI
Sbjct: 163  EGELKFDNQETSKSIDIILFESNKEERDESFQIELFESDGGATLGKLTKCIVTI 2

 Score = 55.1 bits (131), Expect = 9e-07,   Method: Compositional matrix adjust.
 Identities = 49/174 (28%), Positives = 81/174 (46%), Gaps = 2/174 (1%)
 Frame = -1

Query: 2891 LEEGETTAAISITVLEDDIPELKEYFLVNLTHVDLIMAPLTSSPPRLDSEGLTA--QIVI 2948
             E+ ET  +I I +++D   E  E+F V L HV         +P    S G  A  QI I
Sbjct: 490  FEKNETLKSIFIEIVDDCEWEPDEFFFVKL-HV---------TPDDGVSLGNIAICQITI 341

Query: 2949 DANDGAQGMIEWQRNRFEVNETDGVVTLVAQRSRAALGQVSLFMYAQNLEAQAGLDYMCT 3008
              ND   G++ + +  + + E+     +   R+  A G VS+    +++ A  G D+   
Sbjct: 340  -INDDEPGVLAFTKPSYVIKESGLRALIPVSRTGGADGHVSVKWRTKDITAINGKDFKGG 164

Query: 3009 PQILHFTDGERFKHVDVMILDDDMPEGDERFQLLLTNPSPGLELGKNTIALITV 3062
               L F + E  K +D+++ + +  E DE FQ+ L     G  LGK T  ++T+
Sbjct: 163  EGELKFDNQETSKSIDIILFESNKEERDESFQIELFESDGGATLGKLTKCIVTI 2

 Score = 52.8 bits (125), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 33/104 (31%), Positives = 51/104 (49%)
 Frame = -1

Query: 4251 ARITMVASDAPYGRFSFSHEQLHVSEAAQRVNVTVVRSGGSFGRARVLYETGSRTAEAGW 4310
             +IT++  D P G  +F+     + E+  R  + V R+GG+ G   V + T   TA  G 
Sbjct: 355  CQITIINDDEP-GVLAFTKPSYVIKESGLRALIPVSRTGGADGHVSVKWRTKDITAINGK 179

Query: 4311 DFVPASGELLFEAREKMKSLYIDILDDNLPEGPEEFVLAITRVD 4354
            DF    GEL F+ +E  KS+ I + + N  E  E F + +   D
Sbjct: 178  DFKGGEGELKFDNQETSKSIDIILFESNKEERDESFQIELFESD 47

 Score = 51.6 bits (122), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 44/162 (27%), Positives = 75/162 (46%), Gaps = 2/162 (1%)
 Frame = -1

Query: 4321 FEAREKMKSLYIDILDDNLPEGPEEFVLAITRVDLQGRGYDFTIQENGLQIDQPPEIGNI 4380
            FE  E +KS++I+I+DD   E P+EF      V                  D    +GNI
Sbjct: 490  FEKNETLKSIFIEIVDDCEWE-PDEFFFVKLHV----------------TPDDGVSLGNI 362

Query: 4381 SIVRIIIMKNDNAEGIIEF-DPKYTDISVEEDAGVITLPVLRLHGTYGHVSADFSSRGFS 4439
            +I +I I+ ND+  G++ F  P Y    ++E      +PV R  G  GHVS  + ++  +
Sbjct: 361  AICQITII-NDDEPGVLAFTKPSYV---IKESGLRALIPVSRTGGADGHVSVKWRTKDIT 194

Query: 4440 AVPGGYVLHGS-SVTFQHGQNLSFINVSIIDDNGSEFEKQFE 4480
            A+ G     G   + F + +    I++ + + N  E ++ F+
Sbjct: 193  AINGKDFKGGEGELKFDNQETSKSIDIILFESNKEERDESFQ 68

 Score = 48.9 bits (115), Expect = 7e-05,   Method: Compositional matrix adjust.
 Identities = 26/75 (34%), Positives = 40/75 (53%)
 Frame = -1

Query: 2606 IYRTGGSLGQVMVEWRVVGGTATEGLDFMGAGDILTFAEGETKKMAILTILDDSEPEDNE 2665
            + RTGG+ G V V+WR    TA  G DF G    L F   ET K   + + + ++ E +E
Sbjct: 256  VSRTGGADGHVSVKWRTKDITAINGKDFKGGEGELKFDNQETSKSIDIILFESNKEERDE 77

Query: 2666 SILVRLVATEGGSRI 2680
            S  + L  ++GG+ +
Sbjct: 76   SFQIELFESDGGATL 32

 Score = 43.9 bits (102), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 48/169 (28%), Positives = 76/169 (44%)
 Frame = -1

Query: 2756 FSEGTLNKTIFVHLLDDNIPEEKEVYQVVLYDVKTQGVSPAGVALLDAQGYAAVLTVEAS 2815
            F +    K+IF+ ++DD   E  E + V L+     GVS   +A+         +T+   
Sbjct: 490  FEKNETLKSIFIEIVDDCEWEPDEFFFVKLHVTPDDGVSLGNIAICQ-------ITIIND 332

Query: 2816 DEPHGVLNFALSSRFVVLQEANVTIQLFVNREFGSLGAINVTYATVPGIVSLKNNTEGNL 2875
            DEP GVL F   S   V++E+ +   + V+R  G+ G ++V + T       K+ T  N 
Sbjct: 331  DEP-GVLAFTKPS--YVIKESGLRALIPVSRTGGADGHVSVKWRT-------KDITAIN- 185

Query: 2876 AEPESDFIPVVGSLVLEEGETTAAISITVLEDDIPELKEYFLVNLTHVD 2924
                 DF    G L  +  ET+ +I I + E +  E  E F + L   D
Sbjct: 184  ---GKDFKGGEGELKFDNQETSKSIDIILFESNKEERDESFQIELFESD 47

 Score = 41.2 bits (95), Expect = 0.015,   Method: Compositional matrix adjust.
 Identities = 42/157 (26%), Positives = 67/157 (42%), Gaps = 1/157 (0%)
 Frame = -1

Query: 1057 EKGETLVFEVGSREQSISVHVKDDGIPETDEPFYIVLFNSTGDTVVYEYGVATVIIEAND 1116
            EK ETL        +SI + + DD   E DE F++ L  +  D V         I   ND
Sbjct: 487  EKNETL--------KSIFIEIVDDCEWEPDEFFFVKLHVTPDDGVSLGNIAICQITIIND 332

Query: 1117 DPNGVFSLEPIDKAVEEGKTNAFW-ILRHRGHFGNVSVAWQLFQNASLQPGQEFYETSGT 1175
            D  GV +       ++E    A   + R  G  G+VSV W+  ++ +   G++F    G 
Sbjct: 331  DEPGVLAFTKPSYVIKESGLRALIPVSRTGGADGHVSVKWRT-KDITAINGKDFKGGEGE 155

Query: 1176 VNFTDGEETKPVILRAFPDRIPEFNEFYILRLVNISG 1212
            + F + E +K + +  F     E +E + + L    G
Sbjct: 154  LKFDNQETSKSIDIILFESNKEERDESFQIELFESDG 44

 Score = 38.9 bits (89), Expect = 0.073,   Method: Compositional matrix adjust.
 Identities = 33/99 (33%), Positives = 44/99 (44%), Gaps = 1/99 (1%)
 Frame = -1

Query: 3145 KTLRISAILDTEPEMDEHFVCTLF-NPTGGARLGAHVQTLITIFQNQAPLGLFSISAVEN 3203
            K++ I  + D E E DE F   L   P  G  LG      ITI  +  P G+ + +    
Sbjct: 469  KSIFIEIVDDCEWEPDEFFFVKLHVTPDDGVSLGNIAICQITIINDDEP-GVLAFTK--- 302

Query: 3204 SATSIDVEESNRSVYLNVSRTNGLDLTASVQWETVSETA 3242
               S  ++ES     + VSRT G D   SV+W T   TA
Sbjct: 301  --PSYVIKESGLRALIPVSRTGGADGHVSVKWRTKDITA 191

 Score = 37.0 bits (84), Expect = 0.22,   Method: Compositional matrix adjust.
 Identities = 31/102 (30%), Positives = 52/102 (50%), Gaps = 1/102 (0%)
 Frame = -1

Query: 5504 KKSTLISL-QVARDSGTGIMMSVNFITQELRSAETVGRVLISPAVSGKDFVRTEGTLVFE 5562
            K+S L +L  V+R  G    +SV + T+++             A++GKDF   EG L F+
Sbjct: 286  KESGLRALIPVSRTGGADGHVSVKWRTKDI------------TAINGKDFKGGEGELKFD 143

Query: 5563 PGQKSAVLDVVLTPETGSLNKFPKRFQIVLFDPKGGARIDKV 5604
              + S  +D++L     +  +  + FQI LF+  GGA + K+
Sbjct: 142  NQETSKSIDIILFE--SNKEERDESFQIELFESDGGATLGKL 23

 Score = 33.1 bits (74), Expect = 3.3,   Method: Compositional matrix adjust.
 Identities = 22/86 (25%), Positives = 43/86 (50%), Gaps = 6/86 (6%)
 Frame = -1

Query: 3562 IALVGATDSHL------YELTYVSSQSDFIPSLGELIFEPGDKEAIIAVNVLDDTVPEKE 3615
            ++  G  D H+       ++T ++ + DF    GEL F+  +    I + + +    E++
Sbjct: 256  VSRTGGADGHVSVKWRTKDITAINGK-DFKGGEGELKFDNQETSKSIDIILFESNKEERD 80

Query: 3616 ESFRVQLKSPRGGAEIGINSSVRVTV 3641
            ESF+++L    GGA +G  +   VT+
Sbjct: 79   ESFQIELFESDGGATLGKLTKCIVTI 2
>19485
          Length = 434

 Score = 37.7 bits (86), Expect = 0.16,   Method: Compositional matrix adjust.
 Identities = 21/74 (28%), Positives = 39/74 (52%)
 Frame = -1

Query: 3596 GDKEAIIAVNVLDDTVPEKEESFRVQLKSPRGGAEIGINSSVRVTVLANDGAYGVVAFAQ 3655
            G+    ++V ++     E E +F+V+L SP GGAEIG      VT++ ++    +V+   
Sbjct: 431  GETSKNVSVGIIGIQASEHEPNFQVELSSPTGGAEIGKIPKAIVTIINDEEFSSMVSRIA 252

Query: 3656 NSLHKQLEELERDS 3669
                + L+ L+ D+
Sbjct: 251  VKTQRNLDGLQLDT 210
>32189
          Length = 1688

 Score = 33.5 bits (75), Expect = 2.8,   Method: Compositional matrix adjust.
 Identities = 32/134 (23%), Positives = 52/134 (38%), Gaps = 5/134 (3%)
 Frame = -1

Query: 6042 GDLCFIPNIYAALFTAALVPLMCLXXXXXXXIHAYQ----LKPQWKGYDDVFRGRTNAAE 6097
            G  CFI       +  +LV   C+       I        LKP+++            A+
Sbjct: 1670 GAFCFISRNNPLAYYGSLVAPACVVLVINTVIFVLVARVILKPRFQHQKQKEAEGVTPAQ 1491

Query: 6098 IPLILYLFALISMTWLWGGLHMAYRHFWMLVLFVIFNSLQGLYVFVVYFILHNQT-CCPM 6156
            +     +  L+ +TW++G L +         LF I NSLQG  VFV   + + +   C +
Sbjct: 1490 VRGAFTVMFLLGVTWVFGPLAINEAKVVFNYLFCILNSLQGFLVFVFRCLFNPEVRMCWV 1311

Query: 6157 KASYTVEMNGHPGP 6170
            +   T  +    GP
Sbjct: 1310 QLVKTGTLKKRRGP 1269
>13549
          Length = 1298

 Score = 33.5 bits (75), Expect = 3.0,   Method: Composition-based stats.
 Identities = 16/51 (31%), Positives = 28/51 (54%)
 Frame = -2

Query: 2393 VARAVEEGEDVLSYYESPTQGVPDPLWRTWVNVSAVEETQYTCATLCLKER 2443
            +A + ++G     +++SPT+     LWRTW  +SA   T  T +T  + +R
Sbjct: 907  MAMSCQQGRMCACWWDSPTKATGSLLWRTWRPLSATPRT--TASTCRISQR 761
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|160420342|ref|NP_659140.2| ganglioside-induced
differentiation-associated protein 1-like 1 [Mus musculus]
         (367 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

18203                                                                  75   4e-14
12484                                                                  35   0.035
20426                                                                  33   0.17 
18621                                                                  33   0.20 
28643                                                                  31   0.81 
03509                                                                  28   7.5  
14994                                                                  28   8.1  
30643                                                                  28   8.6  
>18203
          Length = 435

 Score = 75.1 bits (183), Expect = 4e-14,   Method: Compositional matrix adjust.
 Identities = 43/110 (39%), Positives = 69/110 (62%), Gaps = 1/110 (0%)
 Frame = +2

Query: 44  KESLVLYHWTQSFSSQKVRLVIAEKGLACEERDVSLPQSEHKEPWFMRLN-LGEEVPVII 102
           ++ + LY++  SFSSQKV L   EKG+  + R VSL   +H EPW+++LN  G  VPV++
Sbjct: 101 EKEITLYYFPTSFSSQKVLLAAYEKGVQFKPRLVSLFHGQHMEPWYVKLNPEGTHVPVLV 280

Query: 103 HRDNIISDYDQIIDYVERTFTGEHVVALMPEAGSPQHARVLQYRELLDAL 152
           H   I+++ ++IIDY++   TG   V L+P+  + +   +   RE L+AL
Sbjct: 281 HGALILNNPEEIIDYIDSLETGMD-VRLVPDIQTSEGQSMAAIREQLNAL 427
>12484
          Length = 912

 Score = 35.4 bits (80), Expect = 0.035,   Method: Compositional matrix adjust.
 Identities = 23/70 (32%), Positives = 38/70 (54%), Gaps = 1/70 (1%)
 Frame = +2

Query: 220 EHDDVSYLKKILGELAMVLDQIEAELEKR-KLENEGQTCELWLCGCAFTLADVLLGATLH 278
           ++D ++  +K+ G+L + LD +  +LEKR   +   +  + WL G  FT AD+ L   L 
Sbjct: 23  KYDIITDEEKVKGQL-LQLDSLFQDLEKRMGADYTDKGGDQWLFGKQFTAADIALSVLLQ 199

Query: 279 RLKFLGLSKK 288
           R   LGL  +
Sbjct: 200 RFTLLGLDTR 229
>20426
          Length = 398

 Score = 33.1 bits (74), Expect = 0.17,   Method: Compositional matrix adjust.
 Identities = 18/49 (36%), Positives = 28/49 (57%), Gaps = 1/49 (2%)
 Frame = -2

Query: 62  RLVIAEKGLACEERDVSLPQSEHKEPWFMRLNLGEEVPVIIHRD-NIIS 109
           RL+++ K +  +  +V L    +K  WF  +N   EVPVIIH   N++S
Sbjct: 394 RLILSAKKVKYDRVNVDL---NNKPDWFFDVNFYGEVPVIIHNGKNVVS 257
>18621
          Length = 515

 Score = 33.1 bits (74), Expect = 0.20,   Method: Compositional matrix adjust.
 Identities = 21/63 (33%), Positives = 34/63 (53%), Gaps = 2/63 (3%)
 Frame = -2

Query: 62  RLVIAEKGLACEERDVSLPQSEHKEPWFMRLNLGEEVPVIIHRDNIISDYDQII--DYVE 119
           RL+++ K +  +  +V L    +K  WF  +N   EVPVIIH    +  Y+ +I  +Y+E
Sbjct: 511 RLILSAKKVKYDRVNVDL---NNKPDWFFDVNFYGEVPVIIHNGKNV--YESLICSEYLE 347

Query: 120 RTF 122
             F
Sbjct: 346 EAF 338
>28643
          Length = 748

 Score = 30.8 bits (68), Expect = 0.81,   Method: Compositional matrix adjust.
 Identities = 36/131 (27%), Positives = 54/131 (41%)
 Frame = +2

Query: 81  QSEHKEPWFMRLNLGEEVPVIIHRDNIISDYDQIIDYVERTFTGEHVVALMPEAGSPQHA 140
           + EHK    ++LN   ++P     D ++++   I DY+E  F  +    L+PE    + A
Sbjct: 77  EKEHKGAEVLKLNQRGQLPTFKDGDLVVNESGAICDYLEFKFPEKR---LLPEDAG-ERA 244

Query: 141 RVLQYRELLDALPMDAYTHGCILHPELTTDSMIPKYATAEIRRHLANATTDLMKLDHEEE 200
           +VLQ R       M       +L+   T    I K            A  D  K +  +E
Sbjct: 245 QVLQ-RVFEQQNLMKKLIENIVLYIFTTPKEKIDK------------AFLDGKKEEARKE 385

Query: 201 PQLSEPYLSKQ 211
            Q  E YLSKQ
Sbjct: 386 LQJWEEYLSKQ 418
>03509
          Length = 2385

 Score = 27.7 bits (60), Expect = 7.5,   Method: Compositional matrix adjust.
 Identities = 20/63 (31%), Positives = 30/63 (47%), Gaps = 4/63 (6%)
 Frame = -2

Query: 105  DNIISDYDQIIDYVERTFTGEHVVALMPEAGSPQHARVLQYRELLDALPMDAYTHG---- 160
            D II       DY++  F+  +++ L+P+   P H   L Y   LDA P+  + H     
Sbjct: 1427 DEIIISLIAYXDYIQXLFSVVNLL*LLPDXC*PFHCXQLPY---LDANPVALFQHCISCM 1257

Query: 161  CIL 163
            CIL
Sbjct: 1256 CIL 1248
>14994
          Length = 901

 Score = 27.7 bits (60), Expect = 8.1,   Method: Compositional matrix adjust.
 Identities = 12/31 (38%), Positives = 15/31 (48%)
 Frame = -1

Query: 31  PDAPEASSPAHWPKESLVLYHWTQSFSSQKV 61
           P A   + P HWP     LYHWT +  +  V
Sbjct: 640 PSAHLLNKPFHWPSLGFRLYHWTDASVTNHV 548
>30643
          Length = 554

 Score = 27.7 bits (60), Expect = 8.6,   Method: Compositional matrix adjust.
 Identities = 12/29 (41%), Positives = 17/29 (58%)
 Frame = +1

Query: 32  DAPEASSPAHWPKESLVLYHWTQSFSSQK 60
           DAP     A WP+ +LV+ H   S S+Q+
Sbjct: 271 DAPSGCGSASWPRSTLVVPHPAVSLSTQR 357
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|21704122|ref|NP_663605.1| pyruvate dehydrogenase
kinase, isoenzyme 3 [Mus musculus]
         (415 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

14731                                                                  75   4e-14
14163                                                                  44   9e-05
14732                                                                  44   1e-04
00888                                                                  30   2.1  
>14731
          Length = 1170

 Score = 75.5 bits (184), Expect = 4e-14,   Method: Compositional matrix adjust.
 Identities = 62/222 (27%), Positives = 103/222 (46%), Gaps = 6/222 (2%)
 Frame = +2

Query: 45  SYMFLRKELPVRLANTMREVNLLPDNLLNRPSVGLVQSWYMQSFLELLEYENKSPEDPRV 104
           S  +L KELPVR+A+ +     LP  +   P++  V   Y+++F  L  +       P +
Sbjct: 551 SAQYLSKELPVRIAHRIAGFRHLPFIVGCNPTILQVHELYIRAFHILSSF-------PLI 709

Query: 105 L-----DNFLNVLINIRNRHNDVVPTMAQGVIEYKEKFGFDPFISSNIQYFLDRFYTNRI 159
           +     + +   L  + + H DVV  +A+G  + ++    +  I +    FLDR  T+R+
Sbjct: 710 MSLKDEEKYSETLRQLLDDHKDVVTLLAEGFAQVRKHIMDENLIRT----FLDRTLTSRL 877

Query: 160 SFRMLINQHTLLFGGDTNPAHPKHIGSIDPTCNVADVVKDAYETAKMLCEQYYLVAPELE 219
             RML   H  L     +   P H+G ++   +   +++   +  K LCE  Y  AP+L 
Sbjct: 878 GIRMLAEHHLSL-----HDEKPNHVGVVNVAFSPRKLIEKKGQFVKTLCEGKYGKAPDLV 1042

Query: 220 VE-EFNAKAPNKPIQVVYVPSHLFHMLFELFKNSMRATVELH 260
           V    N+  P       Y+   L ++L EL KN+ RAT E H
Sbjct: 1043VNGHLNSTFP-------YIQPPLDYILTELLKNAFRATAETH 1147
>14163
          Length = 756

 Score = 44.3 bits (103), Expect = 9e-05,   Method: Compositional matrix adjust.
 Identities = 25/61 (40%), Positives = 37/61 (60%), Gaps = 3/61 (4%)
 Frame = +2

Query: 321 LAGFGYGLPISRLYARYFQGDLKLYSMEGVGTDAVIYLKALSS--ESFER-LPVFNKSAW 377
           + G+G+GLP SR YA Y  G L + SMEG+G+D  + L  + +  ESF   +P   ++A 
Sbjct: 5   MHGYGFGLPSSRAYANYLGGSLTMESMEGIGSDLYLRLGHIDATKESFRI*VPCL*RTAR 184

Query: 378 R 378
           R
Sbjct: 185 R 187
>14732
          Length = 1080

 Score = 43.9 bits (102), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 22/48 (45%), Positives = 31/48 (64%), Gaps = 2/48 (4%)
 Frame = +2

Query: 321 LAGFGYGLPISRLYARYFQGDLKLYSMEGVGTDAVIYLKALSS--ESF 366
           + G+G+GLP SR YA Y  G L + SMEG+G+D  + L  + +  ESF
Sbjct: 5   MHGYGFGLPSSRAYANYLGGSLTMESMEGIGSDLYLRLGHIDATKESF 148
>00888
          Length = 970

 Score = 29.6 bits (65), Expect = 2.1,   Method: Compositional matrix adjust.
 Identities = 19/62 (30%), Positives = 31/62 (50%), Gaps = 7/62 (11%)
 Frame = -3

Query: 359 KALSSESFERLPVFNKSAWRHYKTTPEADDWSN-------PSSEPRDASKYKAKQDKIKS 411
           KAL +  F+++   + + +  Y+T PE  +W+N       P  + RDA +  A  DK  S
Sbjct: 323 KALYTNMFQKMAEKSDAGYNLYQTMPEVGEWNNDMAKNMMPLQDERDAFEDGADGDKKDS 144

Query: 412 NR 413
            R
Sbjct: 143 PR 138
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|52138749|ref|NP_080528.2| cytoplasmic polyadenylation
element binding protein 4 [Mus musculus]
         (729 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

11108                                                                  76   4e-14
02347                                                                  39   0.005
11687                                                                  39   0.010
32386                                                                  37   0.025
03000                                                                  37   0.027
33516                                                                  37   0.030
03406                                                                  35   0.075
00817                                                                  35   0.075
16016                                                                  35   0.076
02809                                                                  35   0.10 
20169                                                                  35   0.11 
17681                                                                  35   0.12 
20053                                                                  33   0.42 
11019                                                                  33   0.60 
01937                                                                  32   0.61 
26197                                                                  32   0.65 
08958                                                                  32   1.0  
00556                                                                  32   1.3  
12350                                                                  31   1.8  
31618                                                                  31   2.0  
33504                                                                  31   2.2  
17175                                                                  30   2.3  
16427                                                                  30   2.5  
18177                                                                  30   3.5  
19868                                                                  29   7.1  
>11108
          Length = 493

 Score = 76.3 bits (186), Expect = 4e-14,   Method: Compositional matrix adjust.
 Identities = 37/105 (35%), Positives = 61/105 (58%), Gaps = 6/105 (5%)
 Frame = -1

Query: 466 RVERYSRKVFVGGLPPDIDEDEITASFRRFGPLIVDWPHKAESKSYFPPKGYAFLLFQDE 525
           R+  YS KVF+GG+P DI E  +   F+ FG + V+WP K +  +   PKGY +++F+ +
Sbjct: 310 RMLNYSPKVFLGGIPWDISEQSLIQIFKPFGSIKVEWPGKEQQAA--QPKGYVYIIFESD 137

Query: 526 SSVQALIDACI------EEDGKLYLCVSSPTIKDKPVQIRPWNLS 564
             V+AL+ AC+      +     +  +SS  IK K V++ PW ++
Sbjct: 136 KQVKALLSACVLQVDDSQNGSNYFFKISSRRIKSKDVEVIPWLIA 2
>02347
          Length = 928

 Score = 39.3 bits (90), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 26/88 (29%), Positives = 42/88 (47%)
 Frame = -3

Query: 473 KVFVGGLPPDIDEDEITASFRRFGPLIVDWPHKAESKSYFPPKGYAFLLFQDESSVQALI 532
           K++VG LPPD  E E+  +F  +G L   W  +        P G+AF+ F+D        
Sbjct: 743 KIYVGDLPPDASEKEVERAFNYYGHLRNVWVARN-------PPGFAFVEFEDTRDAD--- 594

Query: 533 DACIEEDGKLYLCVSSPTIKDKPVQIRP 560
           DA    DG + +C +   ++    ++RP
Sbjct: 593 DAVRALDGTV-VCGNRVRVEHSTGRVRP 513
>11687
          Length = 676

 Score = 38.5 bits (88), Expect = 0.010,   Method: Composition-based stats.
 Identities = 43/173 (24%), Positives = 81/173 (46%), Gaps = 4/173 (2%)
 Frame = +3

Query: 471 SRKVFVGGLPPDIDEDEITASFRRFGPLIVDWPHKAESKSYFPPKGYAFLLFQDESSVQA 530
           S K+FVG +P ++DE+E+   F  +GP  V   +    K+    KG  F+ F        
Sbjct: 147 SIKMFVGQIPRNMDENELRKMFEDYGP--VHSLNILRDKNTGQSKGCCFVTFFTRK---- 308

Query: 531 LIDACIEEDGKLYLCVSSPTIKDKPVQIRPWNLSDSDFVMDGSQPLDPRKTIFVGGVPRP 590
              A ++    L+   + P +   PVQ++P   +DS+   +G + ++ RK +FVG + + 
Sbjct: 309 ---AALDAQNALHNVKTMPMMH-HPVQMKP---ADSE-KRNGERNVEERK-LFVGMLSKK 461

Query: 591 LRAVELAMIMDRLYGGVCYAGIDTDPELKYPKGAGR----VAFSNQQSYIAAI 639
           L   ++ M+ +       +  ID    L+   G  R    + F+++Q  + +I
Sbjct: 462 LSENDVRMLFES------FGSIDDCTVLRDSNGTSRGCAFITFASRQCAMNSI 602
>32386
          Length = 674

 Score = 37.0 bits (84), Expect = 0.025,   Method: Compositional matrix adjust.
 Identities = 20/57 (35%), Positives = 33/57 (57%)
 Frame = +1

Query: 472 RKVFVGGLPPDIDEDEITASFRRFGPLIVDWPHKAESKSYFPPKGYAFLLFQDESSV 528
           RK+F+GGL  + DED + + F  +G  IVD     +S S    +G+ F+ ++D  S+
Sbjct: 301 RKLFIGGLSYETDEDSLRSHFETWGE-IVDCIVMRDSNSK-RSRGFGFITYKDAESI 465
>03000
          Length = 778

 Score = 37.0 bits (84), Expect = 0.027,   Method: Compositional matrix adjust.
 Identities = 20/57 (35%), Positives = 33/57 (57%)
 Frame = +3

Query: 472 RKVFVGGLPPDIDEDEITASFRRFGPLIVDWPHKAESKSYFPPKGYAFLLFQDESSV 528
           RK+F+GGL  + DED + + F  +G  IVD     +S S    +G+ F+ ++D  S+
Sbjct: 87  RKLFIGGLSYETDEDSLRSHFETWGE-IVDCIVMRDSNSK-RSRGFGFITYKDAESI 251
>33516
          Length = 449

 Score = 37.0 bits (84), Expect = 0.030,   Method: Composition-based stats.
 Identities = 20/64 (31%), Positives = 36/64 (56%), Gaps = 2/64 (3%)
 Frame = +1

Query: 473 KVFVGGLPPDIDEDEITASFRRFGPLI--VDWPHKAESKSYFPPKGYAFLLFQDESSVQA 530
           K+FVGGL  D D+D +   F +FG +   +   ++   KS    +G+ F+ F+D S+V  
Sbjct: 157 KIFVGGLSWDTDQDSLQGYFSQFGEITDCIVMMNQQTGKS----RGFGFVSFKDPSTVDV 324

Query: 531 LIDA 534
           ++ +
Sbjct: 325 ILSS 336
>03406
          Length = 1292

 Score = 35.4 bits (80), Expect = 0.075,   Method: Compositional matrix adjust.
 Identities = 19/80 (23%), Positives = 43/80 (53%), Gaps = 1/80 (1%)
 Frame = +3

Query: 472 RKVFVGGLPPDIDEDEITASFRRFGPLI-VDWPHKAESKSYFPPKGYAFLLFQDESSVQA 530
           RK+FVG L P + ++++ + F +FG ++ V+ P+    K     + + F+ F ++ +V+ 
Sbjct: 486 RKIFVGKLDPGVPQEDVESYFAKFGKVVNVELPY---DKVKDQRRAFCFVEFDNDKTVKK 656

Query: 531 LIDACIEEDGKLYLCVSSPT 550
           +++    + G   + V   T
Sbjct: 657 VLEQTSHKIGGQEVDVKKAT 716

 Score = 32.7 bits (73), Expect = 0.54,   Method: Compositional matrix adjust.
 Identities = 22/88 (25%), Positives = 41/88 (46%)
 Frame = +3

Query: 445 GDQPLHSGLGSPHCFTHQNGERVERYSRKVFVGGLPPDIDEDEITASFRRFGPLIVDWPH 504
           GDQ + +G          + E      RK+FVGGL  +     +   F +FG  +     
Sbjct: 186 GDQAMETG---------GDAEEENEDDRKIFVGGLSWETXSKHLREYFEKFGE-VTSCTL 335

Query: 505 KAESKSYFPPKGYAFLLFQDESSVQALI 532
           K +  S    +G+ F++F++ ++V A++
Sbjct: 336 KTDLDSG-KSRGFGFVVFKEAATVDAVV 416
>00817
          Length = 2606

 Score = 35.4 bits (80), Expect = 0.075,   Method: Compositional matrix adjust.
 Identities = 21/73 (28%), Positives = 37/73 (50%), Gaps = 4/73 (5%)
 Frame = -2

Query: 463  NGERVERYSRKVFVGGLPPDIDEDEITASFRRFGP----LIVDWPHKAESKSYFPPKGYA 518
            N ER    +RKVF+GG+ PD DE  + + F ++G     ++V  P    S+       ++
Sbjct: 2566 NAER----NRKVFIGGMHPDTDESSLRSYFEKYGDIRECIVVKDPATKRSRC------FS 2417

Query: 519  FLLFQDESSVQAL 531
            F+ F +  +V  +
Sbjct: 2416 FITFGNAENVDEV 2378
>16016
          Length = 1364

 Score = 35.4 bits (80), Expect = 0.076,   Method: Compositional matrix adjust.
 Identities = 21/73 (28%), Positives = 37/73 (50%), Gaps = 4/73 (5%)
 Frame = -2

Query: 463  NGERVERYSRKVFVGGLPPDIDEDEITASFRRFGP----LIVDWPHKAESKSYFPPKGYA 518
            N ER    +RKVF+GG+ PD DE  + + F ++G     ++V  P    S+       ++
Sbjct: 1324 NAER----NRKVFIGGMHPDTDESSLRSYFEKYGDIRECIVVKDPATKRSRC------FS 1175

Query: 519  FLLFQDESSVQAL 531
            F+ F +  +V  +
Sbjct: 1174 FITFGNAENVDEV 1136
>02809
          Length = 1475

 Score = 35.0 bits (79), Expect = 0.10,   Method: Compositional matrix adjust.
 Identities = 22/63 (34%), Positives = 32/63 (50%), Gaps = 4/63 (6%)
 Frame = -1

Query: 473  KVFVGGLPPDIDEDEITASFRRFGPLIVDWPHKAESKSYFPPKGYAFLLFQD----ESSV 528
            KV+VG L     + E+   F ++GPL   W  +        P G+AF+ F+D    E +V
Sbjct: 1331 KVYVGELGHGCAKQELEDKFAKYGPLKNVWVAR-------RPAGFAFVEFEDNRDAEDAV 1173

Query: 529  QAL 531
            QAL
Sbjct: 1172 QAL 1164
>20169
          Length = 1364

 Score = 35.0 bits (79), Expect = 0.11,   Method: Compositional matrix adjust.
 Identities = 24/68 (35%), Positives = 34/68 (50%), Gaps = 4/68 (5%)
 Frame = -1

Query: 473  KVFVGGLPPDIDEDEITASFRRFGPLIVDWPHKAESKSYFPPKGYAFLLFQD----ESSV 528
            KV+VG L     + E+   F ++GPL   W  +        P G+AF+ F+D    E +V
Sbjct: 1067 KVYVGELGHGCAKQELEDKFAKYGPLKNVWVARR-------PAGFAFVEFEDNRDAEDAV 909

Query: 529  QALIDACI 536
            QAL  A I
Sbjct: 908  QALDGARI 885
>17681
          Length = 964

 Score = 34.7 bits (78), Expect = 0.12,   Method: Compositional matrix adjust.
 Identities = 21/67 (31%), Positives = 34/67 (50%), Gaps = 2/67 (2%)
 Frame = +2

Query: 474 VFVGGLPPDIDEDEIT-ASFRRFGPLIVDWPHKAESKSYFPPKGYAFLLF-QDESSVQAL 531
           V+ GG PP++  DE+    F +FGP+        +    F  KG+AF+ F   E++ +A+
Sbjct: 428 VYCGGFPPNVISDELMHKHFMQFGPI--------QDVRVFKDKGFAFIKFVTKEAAARAI 583

Query: 532 IDACIEE 538
               I E
Sbjct: 584 EHTHISE 604

 Score = 33.9 bits (76), Expect = 0.26,   Method: Compositional matrix adjust.
 Identities = 22/66 (33%), Positives = 36/66 (54%), Gaps = 8/66 (12%)
 Frame = +2

Query: 474 VFVGGLPPDIDEDEITASFRRFGPL----IVDWPHKAESKSYFPPKGYAFLLF----QDE 525
           +FVG L P+I+ + +  +F  FG +    IV  P   +S      KGYAF+ F    + E
Sbjct: 38  IFVGDLSPEIETETLREAFAPFGEISNCRIVRDPQTMKS------KGYAFVSFVKKAEAE 199

Query: 526 SSVQAL 531
           +++QA+
Sbjct: 200 NAIQAM 217
>20053
          Length = 406

 Score = 33.1 bits (74), Expect = 0.42,   Method: Composition-based stats.
 Identities = 13/18 (72%), Positives = 15/18 (83%)
 Frame = -3

Query: 709 FHKPLVKEGGDRPRHISF 726
           +HKPLVKEG DRPR + F
Sbjct: 404 YHKPLVKEGADRPRAVPF 351
>11019
          Length = 552

 Score = 32.7 bits (73), Expect = 0.60,   Method: Composition-based stats.
 Identities = 23/85 (27%), Positives = 42/85 (49%), Gaps = 5/85 (5%)
 Frame = -1

Query: 459 FTHQNGERVERYSRKVFVGGLPPDIDEDEITASFRRFG-----PLIVDWPHKAESKSYFP 513
           F  ++  R+   ++K+FVGGL      ++I   F+ +G      L+ D   K  S+    
Sbjct: 273 FPRKSNPRMVTKTKKIFVGGLSSSTTVEDIKNYFKAYGTIEEATLMFD---KVTSRH--- 112

Query: 514 PKGYAFLLFQDESSVQALIDACIEE 538
            +G+AF+ F +ES+V  + +    E
Sbjct: 111 -RGFAFVTFDNESTVDKVCEIHFHE 40
>01937
          Length = 1320

 Score = 32.3 bits (72), Expect = 0.61,   Method: Compositional matrix adjust.
 Identities = 22/88 (25%), Positives = 41/88 (46%)
 Frame = -1

Query: 446  DQPLHSGLGSPHCFTHQNGERVERYSRKVFVGGLPPDIDEDEITASFRRFGPLIVDWPHK 505
            D  L +G   PHC    + + +   + K+FVGGL      ++    F+ +G   ++    
Sbjct: 1275 DNVLANG---PHCI---DSKTMVTKTSKIFVGGLSSSTTVEDXKNYFKAYGT--IEEATL 1120

Query: 506  AESKSYFPPKGYAFLLFQDESSVQALID 533
               K     +G+AF+ F +ES+V  + +
Sbjct: 1119 MFDKVTSRHRGFAFVTFDNESTVDKVCE 1036
>26197
          Length = 1365

 Score = 32.3 bits (72), Expect = 0.65,   Method: Compositional matrix adjust.
 Identities = 17/61 (27%), Positives = 32/61 (52%)
 Frame = -2

Query: 472  RKVFVGGLPPDIDEDEITASFRRFGPLIVDWPHKAESKSYFPPKGYAFLLFQDESSVQAL 531
            RK+FVGGL  +     +   F +FG  +     K +  S    +G+ F++F++  +V A+
Sbjct: 1298 RKIFVGGLSWETSSKHLREYFEKFGE-VTSCTLKTDLDSG-KSRGFGFVVFKEAVTVDAV 1125

Query: 532  I 532
            +
Sbjct: 1124 V 1122

 Score = 29.3 bits (64), Expect = 5.2,   Method: Compositional matrix adjust.
 Identities = 16/67 (23%), Positives = 38/67 (56%), Gaps = 1/67 (1%)
 Frame = -3

Query: 468  ERYSRKVFVGGLPPDIDEDEITASFRRFGPLI-VDWPHKAESKSYFPPKGYAFLLFQDES 526
            ER   + FVG L P + ++++ + F +FG ++ V+ P+    K     + + F+ F ++ 
Sbjct: 1063 ERA*GRFFVGKLDPGVPQEDVESYFAKFGKVVNVELPY---DKVKDQRRAFCFVEFDNDK 893

Query: 527  SVQALID 533
            +V+ +++
Sbjct: 892  TVKKVLE 872
>08958
          Length = 680

 Score = 32.0 bits (71), Expect = 1.0,   Method: Compositional matrix adjust.
 Identities = 21/64 (32%), Positives = 29/64 (45%), Gaps = 21/64 (32%)
 Frame = +2

Query: 466 RVERYSRK-------VFVGGLPPDIDEDEITASF--------------RRFGPLIVDWPH 504
           RV+ Y RK       +FVG L PD+ ED+    F              R FG + +D+ H
Sbjct: 29  RVKEYRRKKFTGRCRLFVGNLTPDVSEDDFKKLFSPFGEVSEAYVNSGRGFGFIRLDYRH 208

Query: 505 KAES 508
            AE+
Sbjct: 209 NAEA 220
>00556
          Length = 2189

 Score = 31.6 bits (70), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 13/32 (40%), Positives = 19/32 (59%)
 Frame = +3

Query: 467 VERYSRKVFVGGLPPDIDEDEITASFRRFGPL 498
           V+    K+F+GGLP  + ED++      FGPL
Sbjct: 744 VQDSDHKIFMGGLPSYLSEDQMKELLLSFGPL 839
>12350
          Length = 975

 Score = 30.8 bits (68), Expect = 1.8,   Method: Compositional matrix adjust.
 Identities = 19/62 (30%), Positives = 31/62 (50%), Gaps = 1/62 (1%)
 Frame = -2

Query: 471 SRKVFVGGLPPDIDEDEITASFRRFGPLI-VDWPHKAESKSYFPPKGYAFLLFQDESSVQ 529
           +RK+FVG    D+  D++   F +FG ++ V  P         P + +AF+ F D    Q
Sbjct: 365 NRKIFVGRCTDDMTADDLRQFFSKFGEVVDVFIPR--------PFRAFAFVSFADPEVAQ 210

Query: 530 AL 531
           +L
Sbjct: 209 SL 204
>31618
          Length = 716

 Score = 30.8 bits (68), Expect = 2.0,   Method: Composition-based stats.
 Identities = 12/24 (50%), Positives = 17/24 (70%)
 Frame = +3

Query: 473 KVFVGGLPPDIDEDEITASFRRFG 496
           K+FVGGL  +I ++EI   F +FG
Sbjct: 537 KIFVGGLTTEISDEEIKTYFSQFG 608
>33504
          Length = 282

 Score = 30.8 bits (68), Expect = 2.2,   Method: Composition-based stats.
 Identities = 11/26 (42%), Positives = 18/26 (69%)
 Frame = +1

Query: 474 VFVGGLPPDIDEDEITASFRRFGPLI 499
           VF+GGLP D+ E +I   F ++G ++
Sbjct: 175 VFIGGLPYDLTEGDIICVFSQYGEIV 252
>17175
          Length = 512

 Score = 30.4 bits (67), Expect = 2.3,   Method: Composition-based stats.
 Identities = 12/28 (42%), Positives = 20/28 (71%)
 Frame = -3

Query: 471 SRKVFVGGLPPDIDEDEITASFRRFGPL 498
           S K+FVG +P ++DE+E+   F  +GP+
Sbjct: 93  SIKMFVGQIPRNMDENELRKMFEDYGPV 10
>16427
          Length = 1313

 Score = 30.4 bits (67), Expect = 2.5,   Method: Compositional matrix adjust.
 Identities = 19/72 (26%), Positives = 35/72 (48%)
 Frame = +1

Query: 473 KVFVGGLPPDIDEDEITASFRRFGPLIVDWPHKAESKSYFPPKGYAFLLFQDESSVQALI 532
           K+FVGGL  +IDE  +   F +FG +      + + +     +G+ F+ +++    +   
Sbjct: 139 KLFVGGLAEEIDEKVLEREFSKFGRITESMVIRDKVRQV--SRGFGFVTYENPMDAE--- 303

Query: 533 DACIEEDGKLYL 544
           +A    DGK  L
Sbjct: 304 EAVKHMDGKEIL 339
>18177
          Length = 552

 Score = 30.0 bits (66), Expect = 3.5,   Method: Composition-based stats.
 Identities = 10/27 (37%), Positives = 15/27 (55%)
 Frame = -3

Query: 667 CDECQGARCGGKFAPFFCANVTCLQYY 693
           C +C   RC  + APF+C  ++ L  Y
Sbjct: 82  CSQCDCTRCARQQAPFWCQTISRLSRY 2
>19868
          Length = 434

 Score = 28.9 bits (63), Expect = 7.1,   Method: Composition-based stats.
 Identities = 23/74 (31%), Positives = 35/74 (47%), Gaps = 5/74 (6%)
 Frame = +2

Query: 473 KVFVGGLPPDIDEDEITASFRRFGP----LIVDWPHKAESKSYFPPKGYAFLLFQDESSV 528
           K+FVGGL      + +   F +FG     +++  P    S      +G+ F+ F D +SV
Sbjct: 2   KMFVGGLSWQTSPESLRDYFNKFGEITEVMVMKDPTTRRS------RGFGFITFGDPASV 163

Query: 529 -QALIDACIEEDGK 541
            + L  A  E DGK
Sbjct: 164 DKVLAQATHELDGK 205
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|67514549|ref|NP_034551.2| hexosaminidase A [Mus
musculus]
         (528 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

32384                                                                  76   4e-14
02844                                                                  30   3.0  
23270                                                                  29   3.7  
02874                                                                  29   5.7  
>32384
          Length = 893

 Score = 75.9 bits (185), Expect = 4e-14,   Method: Compositional matrix adjust.
 Identities = 42/100 (42%), Positives = 56/100 (56%), Gaps = 6/100 (6%)
 Frame = +3

Query: 430 WKDMYKVEPLA-FHGTPEQKALVIGGEACMWGEYVDSTNLVPRLWPRAGAVAERLWSS-N 487
           W+++Y+  P         ++  V+GGEAC+W E VD   L  RLWPRA A+AERLWS  N
Sbjct: 21  WQNVYRHRPWERMRLDKRRRKQVLGGEACLWTEQVDENQLDSRLWPRAAALAERLWSDPN 200

Query: 488 LTTNIDF----AFKRLSHFRCELVRRGIQAQPISVGYCEQ 523
              + D      F+R+S FR  LV  GI A+ +   YC Q
Sbjct: 201 DDHDFDIVRPEVFRRISLFRNRLVELGINAEALFPKYCAQ 320
>02844
          Length = 918

 Score = 29.6 bits (65), Expect = 3.0,   Method: Compositional matrix adjust.
 Identities = 18/45 (40%), Positives = 24/45 (53%), Gaps = 1/45 (2%)
 Frame = -3

Query: 280 GSHLSGTFGPVNPSLNSTYDFMSTLFLE-ISSVFPDFYLHLGGDE 323
           G++L  T  P +P      +F  T  L+ I  VFPDF+LHL   E
Sbjct: 454 GNNLDSTDSPSSPP-----EFTYTALLDRIHEVFPDFHLHLAATE 335
>23270
          Length = 928

 Score = 29.3 bits (64), Expect = 3.7,   Method: Compositional matrix adjust.
 Identities = 18/45 (40%), Positives = 24/45 (53%), Gaps = 1/45 (2%)
 Frame = +3

Query: 280 GSHLSGTFGPVNPSLNSTYDFMSTLFLE-ISSVFPDFYLHLGGDE 323
           G++L  T  P +P      +F  T  L+ I  VFPDF+LHL   E
Sbjct: 681 GNNLDSTDSPSSPP-----EFTYTALLDRIHEVFPDFHLHLAATE 800
>02874
          Length = 909

 Score = 28.9 bits (63), Expect = 5.7,   Method: Compositional matrix adjust.
 Identities = 18/56 (32%), Positives = 24/56 (42%), Gaps = 11/56 (19%)
 Frame = -1

Query: 29  YIQTYHRRYTLYPNNFQFRYHVSSAAQAGCVVLDEAFR-----------RYRNLLF 73
           YI   ++ Y L P NF F  H     +  C V+ + F+           RYR LLF
Sbjct: 225 YIYNKNKEYDLSPGNFYFIIHQIXLTRXLCTVIVDVFKCWVMFVSIFVSRYRQLLF 58
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|27369633|ref|NP_766057.1| chloride intracellular
channel 6 [Mus musculus]
         (596 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

08339                                                                  76   5e-14
>08339
          Length = 2500

 Score = 75.9 bits (185), Expect = 5e-14,   Method: Compositional matrix adjust.
 Identities = 72/233 (30%), Positives = 104/233 (44%), Gaps = 21/233 (9%)
 Frame = +1

Query: 377 GNCPFSQRLFMILWLKG-----VIFNVTTV--DLKRKPADLQNLAPGTNPPFMTFDGE-- 427
           G+CP  Q  FMI  L G     + F V TV  D   K   ++       P  M  +G   
Sbjct: 55  GSCPVCQHWFMITCLLGDRQNDIDFKVYTVQADCPPKNFGVEQGWSKLFPVVMVLEGCDK 234

Query: 428 -------VKTD-VNKIEEFLEEKLVPPRYPKLGTQHPESNSAGNDVFAKFSAFIKN-TKK 478
                   K D  +++E F E   +   YP L   +  +  A   V   ++AF K  + K
Sbjct: 235 KGQDLAGTKYDTFDELETFFES--INREYPALKRHNAPNVGAMKVVEDVYTAFNKCLSTK 408

Query: 479 DANEIYEKNLLRALKKLDSYLNSPLPDEIDADSSEDVTVSQRKFLDGDELTLADCNLLPK 538
           D      K L+  L+K++ +L      E ++DS         KFL  D ++ ADC+LLP+
Sbjct: 409 DP-----KRLMTQLRKINEFL------EEESDS---------KFLVDDVMSFADCHLLPR 528

Query: 539 LHIIKIVAKKYRDFEF---PSEMTGIWRYLNNAYARDEFTNTCPADREIEHAY 588
           L  I++  K Y    F   P E T IWRYL  AY  + F +T P+D++I   Y
Sbjct: 529 LQHIRVAGKFYMKDTFDDIPKEFTAIWRYLAEAYKTEAFRSTVPSDQDILFHY 687
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|171184435|ref|NP_067320.2| protein tyrosine
phosphatase-like A domain containing 1 [Mus musculus]
         (362 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

17525                                                                  64   7e-14
06220                                                                  57   9e-09
14232                                                                  45   5e-05
>17525
          Length = 458

 Score = 64.3 bits (155), Expect(2) = 7e-14,   Method: Compositional matrix adjust.
 Identities = 28/75 (37%), Positives = 45/75 (60%)
 Frame = -2

Query: 4   QVLTPHVYWAQRHRELYLRVELSDVQNPAISITDNVLHFKAQGHGAKGDNVYEFHLEFLD 63
           + LTP VYW Q +  +YL++ L + ++  + +T++ L FKA G G+KG+N Y   LEF  
Sbjct: 442 ETLTPFVYWGQTNDIIYLKINLRNTEDEEVQLTEDSLSFKANGEGSKGNNPYSVQLEFYL 263

Query: 64  LVKPEPAYRLTQRQV 78
            + PE A    + +V
Sbjct: 262 PIDPEKAGTAERTRV 218

 Score = 30.4 bits (67), Expect(2) = 7e-14,   Method: Compositional matrix adjust.
 Identities = 17/47 (36%), Positives = 27/47 (57%)
 Frame = -1

Query: 71  YRLTQRQVNITVQKKGSHWWERLTKQEKRPLFLAPDFDRWLDESDAE 117
           YR T   V   ++K  S  W RLT+Q  +  +L  DFD+++ E ++E
Sbjct: 239 YRRTDACVEFQIKKSVSETWPRLTEQRLKLPWLKIDFDKFMVEGESE 99
>06220
          Length = 1052

 Score = 57.4 bits (137), Expect = 9e-09,   Method: Compositional matrix adjust.
 Identities = 37/119 (31%), Positives = 64/119 (53%), Gaps = 3/119 (2%)
 Frame = -3

Query: 2   ETQVLTPHVYWAQRHRELYLRVELSDVQNPAISITDNVLHFKAQGHGAKGDNVYEFHLE- 60
           E   L   + WAQR  ++++ V L + ++ A ++T+    FK  G G   +  +E  L  
Sbjct: 990 EKSCLPAPLLWAQRKDKVWITVVLENCKDGAHALTEQTFSFK--GTGGTENLKHEVDLTL 817

Query: 61  FLDLVKPEPAYRLTQRQVNITVQKKGSH--WWERLTKQEKRPLFLAPDFDRWLDESDAE 117
           F ++V  +   + + RQ   T+ KK +   +W RL K++K+  +L  DF+RW DE D+E
Sbjct: 816 FGEIVPDKSTCQKSDRQAFYTLAKKDTDAPYWPRLIKEQKKLHYLKTDFNRWKDEDDSE 640
>14232
          Length = 930

 Score = 45.1 bits (105), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 25/96 (26%), Positives = 51/96 (53%), Gaps = 3/96 (3%)
 Frame = -1

Query: 25  LSDVQNPAISITDNVLHFKAQGHGAKGDNVYEFHLEFLDLVKPEPA-YRLTQRQVNITVQ 83
           L +  +P I + +  LHF   G G   +  ++  ++F D + PE + ++   R   + + 
Sbjct: 927 LENCPHPNIELKEQSLHF--SGKGGTENLAHDVTVDFFDKINPETSRHQSNDRHTTLVLM 754

Query: 84  K--KGSHWWERLTKQEKRPLFLAPDFDRWLDESDAE 117
           K  + + +W RLTK++ +  ++  DF++W DE D +
Sbjct: 753 KADQTAPFWPRLTKEKIKCHYIKTDFNKWKDEDDTD 646
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31560819|ref|NP_032446.2| potassium voltage gated
channel, Shab-related subfamily, member 1 [Mus musculus]
         (857 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

26719                                                                  76   7e-14
33196                                                                  73   6e-13
31326                                                                  61   2e-09
07918                                                                  33   0.70 
>26719
          Length = 394

 Score = 75.9 bits (185), Expect = 7e-14,   Method: Composition-based stats.
 Identities = 43/110 (39%), Positives = 60/110 (54%), Gaps = 8/110 (7%)
 Frame = -3

Query: 300 RIMRILRILKLARHSTGLQSLGFTLRRSYNELGLLILFLAMGIMIFSSLVFFAE------ 353
           R +R++R L+L      L  +    RR + EL LL++  A    +F +L FF E      
Sbjct: 350 RWLRMIRYLELLDWDASLHVMWVATRRCHQELLLLLVVFAGLSTLFGALTFFLEHHSGSN 171

Query: 354 -KDEDDTKFKS-IPASFWWATITMTTVGYGDIYPKTLLGKIVGGLCCIAG 401
            K  +   F S +  S +WA ITMTTVGYGDI P T LG+++G LC + G
Sbjct: 170 EKGHNSRPFASDLTGSVYWAIITMTTVGYGDITPSTTLGRVMGVLCSLIG 21
>33196
          Length = 373

 Score = 72.8 bits (177), Expect = 6e-13,   Method: Composition-based stats.
 Identities = 41/117 (35%), Positives = 57/117 (48%)
 Frame = -3

Query: 32  RVRLNVGGLAHEVLWRTLDRLPRTRLGKLRDCNTHDSLLQVCDDYSLEDNEYFFDRHPGA 91
           ++++NV G   E    TL++ P T LG     N  +        Y  E  EYFFDR P  
Sbjct: 356 KLKINVSGRKFETWRTTLEKYPDTLLGS----NEKEFF------YDEESKEYFFDRDPDL 207

Query: 92  FTSILNFYRTGRLHMMEEMCALSFSQELDYWGIDEIYLESCCQARYHQKKEQMNEEL 148
           F  ILN+YRTG LH  +  C  ++  EL ++GI    +  CC   Y  +K +  E L
Sbjct: 206 FRHILNYYRTGSLHYPKHECISAYDDELAFFGIMPEIIGDCCYEDYRDRKRENAERL 36
>31326
          Length = 383

 Score = 60.8 bits (146), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 23/53 (43%), Positives = 34/53 (64%)
 Frame = -2

Query: 85  FDRHPGAFTSILNFYRTGRLHMMEEMCALSFSQELDYWGIDEIYLESCCQARY 137
           FDR P  F +ILN++ T  LH+  ++C L+   ELD+WGI E  ++ CC  +Y
Sbjct: 325 FDRDPDVFRAILNYFTTDELHLPIQVCGLAVKNELDFWGIKEHEIQRCCWTKY 167
>07918
          Length = 1188

 Score = 32.7 bits (73), Expect = 0.70,   Method: Composition-based stats.
 Identities = 19/58 (32%), Positives = 29/58 (50%)
 Frame = -3

Query: 605  SHSPLASLSGKSGGSTAPEVGWRGALGASGGRLMETNPIPEASRSGFFVESPRSSMKT 662
            S +P    SG   G   P  G  G  G +GG++++TN    A+   F + +PR+S  T
Sbjct: 1108 SSNPTGGWSGWRLGCVHPHCGQSGT-GVAGGQIIQTNIGQSAAPQSFVLITPRASTPT 938
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|21312550|ref|NP_082324.1| solute carrier family 25,
member 35 [Mus musculus]
         (300 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

18977                                                                  74   8e-14
33703                                                                  67   6e-12
10615                                                                  59   2e-09
02771                                                                  57   1e-08
03676                                                                  57   1e-08
00831                                                                  56   2e-08
07963                                                                  55   3e-08
06435                                                                  48   4e-06
06258                                                                  47   1e-05
13320                                                                  46   2e-05
11720                                                                  45   3e-05
17936                                                                  44   9e-05
13322                                                                  42   2e-04
11735                                                                  41   8e-04
00983                                                                  39   0.002
03275                                                                  38   0.005
11205                                                                  37   0.011
05312                                                                  35   0.034
23802                                                                  35   0.036
13140                                                                  33   0.12 
31492                                                                  33   0.12 
03571                                                                  33   0.15 
18662                                                                  31   0.60 
24291                                                                  28   5.3  
>18977
          Length = 497

 Score = 73.9 bits (180), Expect = 8e-14,   Method: Compositional matrix adjust.
 Identities = 43/125 (34%), Positives = 68/125 (54%), Gaps = 1/125 (0%)
 Frame = -3

Query: 175 RVVIGSSTQLCTFSSIKDLLSQWEIFPPQSWKVALAAAMVSGVAIVVAMTPFDVASTRLY 234
           R ++ ++ QL ++S  K LL     F    + +   A+M+SG+    A  P D+A TR+ 
Sbjct: 489 RAMVVNAAQLASYSQAKQLLMGTGYFHDGLF-LHFVASMISGLITTAASMPVDIAKTRIQ 313

Query: 235 N-QPTDTRGKGLMYRGILDALLQTARTEGFFGMYKGIGASYFRLGPHTILSLFFWDQLRS 293
           N +  D + +   Y+G LD L +  R EGFF ++KG    Y RLGPHT+L+  F +Q+  
Sbjct: 312 NMKMIDGKPE---YKGALDVLGKVIRNEGFFSLWKGFTPYYARLGPHTVLTFIFLEQMNI 142

Query: 294 FYNTY 298
            Y  +
Sbjct: 141 AYRKH 127
>33703
          Length = 421

 Score = 67.4 bits (163), Expect = 6e-12,   Method: Compositional matrix adjust.
 Identities = 32/87 (36%), Positives = 52/87 (59%)
 Frame = -2

Query: 211 AAMVSGVAIVVAMTPFDVASTRLYNQPTDTRGKGLMYRGILDALLQTARTEGFFGMYKGI 270
           A++ SG+   +  TP DV  TR+ NQPT   GKGL Y G +D L++T + EGF  +YKG+
Sbjct: 342 ASICSGLVAALMGTPADVVKTRIMNQPTK-DGKGLQYSGSVDCLVKTVKKEGFLALYKGL 166

Query: 271 GASYFRLGPHTILSLFFWDQLRSFYNT 297
              + R+ P +++    ++++R    T
Sbjct: 165 LPIWARMAPWSLVFWLSYEEVRKLTGT 85
>10615
          Length = 1795

 Score = 59.3 bits (142), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 62/278 (22%), Positives = 107/278 (38%), Gaps = 3/278 (1%)
 Frame = +3

Query: 2   DFLMSGVAACGACVFTNPLEVVKTRMQLQGELQAPGTYQRHYRNVFHAFFTIGKVDGLAA 61
           +F +SGVAA  +     P+E +K  +Q Q E+   G     Y+ V        + +G+  
Sbjct: 231 NFALSGVAAVISKTAAAPIERIKLLVQNQDEMIKAGRLSEPYKGVIDCTVRTFRTEGILP 410

Query: 62  LQKGLGPALLYQFLMNGIRLGTYGLAESRGYLHTNEGTHSPVRSXXXXXXXXXXXXXXXS 121
             +G     L  F    +        + +    T+ G    V+                 
Sbjct: 411 FWRGNLANCLRYFPTQALNFAFKD--KVKAMFKTSPGESYVVKFSKNIFSGGVAGALSLC 584

Query: 122 PIYMV---KTHLQAQAASEIAVGHQYKHQGMFQALTEIGQKHGLVGLWRGAVGGLPRVVI 178
            +Y +   +T L   A S    G + +  G+    T+  +  G VGL+RG V     +V+
Sbjct: 585 FVYSLDYARTRLANDAKSAGKGGGERQFNGLIDVYTKTLKSDGFVGLYRGFVISCVGIVV 764

Query: 179 GSSTQLCTFSSIKDLLSQWEIFPPQSWKVALAAAMVSGVAIVVAMTPFDVASTRLYNQPT 238
                   + S+K ++   +     S+ +  A  + SG+       P D    R+     
Sbjct: 765 YRGFYFGLYDSLKPIMLGDDANVFMSFCLGYAVTVSSGLL----SYPIDTIRRRMMM--- 923

Query: 239 DTRGKGLMYRGILDALLQTARTEGFFGMYKGIGASYFR 276
            T G+ + Y+G +D  +Q  + EGF  M KG GA+  R
Sbjct: 924 -TSGQAVKYKGSMDCAMQIIKNEGFMSMMKGAGANILR 1034

 Score = 41.2 bits (95), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 26/89 (29%), Positives = 46/89 (51%), Gaps = 5/89 (5%)
 Frame = +3

Query: 214 VSGVAIVVAMT---PFDVASTRLYNQPTDTRGKGLM--YRGILDALLQTARTEGFFGMYK 268
           +SGVA V++ T   P +     + NQ    +   L   Y+G++D  ++T RTEG    ++
Sbjct: 240 LSGVAAVISKTAAAPIERIKLLVQNQDEMIKAGRLSEPYKGVIDCTVRTFRTEGILPFWR 419

Query: 269 GIGASYFRLGPHTILSLFFWDQLRSFYNT 297
           G  A+  R  P   L+  F D++++ + T
Sbjct: 420 GNLANCLRYFPTQALNFAFKDKVKAMFKT 506
>02771
          Length = 1591

 Score = 57.0 bits (136), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 60/278 (21%), Positives = 107/278 (38%), Gaps = 3/278 (1%)
 Frame = -1

Query: 2    DFLMSGVAACGACVFTNPLEVVKTRMQLQGELQAPGTYQRHYRNVFHAFFTIGKVDGLAA 61
            +F +SGVAA  +     P+E +K  +Q Q E+   G     Y+ V        + +G+  
Sbjct: 1432 NFALSGVAAVISKTAAAPIERIKLLVQNQDEMIKAGRLSEPYKGVIDCTVRTFRTEGVLP 1253

Query: 62   LQKGLGPALLYQFLMNGIRLGTYGLAESRGYLHTNEGTHSPVRSXXXXXXXXXXXXXXXS 121
              +G     L  F    +        + +    ++ G     +                 
Sbjct: 1252 FWRGNLANCLRYFPTQALNFAFKD--KVKAMFKSSPGESYVAKFSKNIFSGGVAGALSLC 1079

Query: 122  PIYMV---KTHLQAQAASEIAVGHQYKHQGMFQALTEIGQKHGLVGLWRGAVGGLPRVVI 178
             +Y +   +T L   A S    G + +  G+    T+  +  G+VGL+RG V     +V+
Sbjct: 1078 FVYSLDYARTRLANDAKSAGKGGGERQFNGLIDVYTKTLKSDGIVGLYRGFVISCVGIVV 899

Query: 179  GSSTQLCTFSSIKDLLSQWEIFPPQSWKVALAAAMVSGVAIVVAMTPFDVASTRLYNQPT 238
                    + S+K ++   +     S+ +  A  + SG+       P D    R+     
Sbjct: 898  YRGFYFGLYDSLKPIMLGDDANVFMSFCLGYAVTVSSGLL----SYPIDTIRRRMMM--- 740

Query: 239  DTRGKGLMYRGILDALLQTARTEGFFGMYKGIGASYFR 276
             T G+ + Y+G +D  +Q  + EGF  M KG GA+  R
Sbjct: 739  -TSGQAVKYKGSMDCAMQIIKNEGFMSMMKGAGANILR 629

 Score = 39.7 bits (91), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 25/89 (28%), Positives = 46/89 (51%), Gaps = 5/89 (5%)
 Frame = -1

Query: 214  VSGVAIVVAMT---PFDVASTRLYNQPTDTRGKGLM--YRGILDALLQTARTEGFFGMYK 268
            +SGVA V++ T   P +     + NQ    +   L   Y+G++D  ++T RTEG    ++
Sbjct: 1423 LSGVAAVISKTAAAPIERIKLLVQNQDEMIKAGRLSEPYKGVIDCTVRTFRTEGVLPFWR 1244

Query: 269  GIGASYFRLGPHTILSLFFWDQLRSFYNT 297
            G  A+  R  P   L+  F D++++ + +
Sbjct: 1243 GNLANCLRYFPTQALNFAFKDKVKAMFKS 1157
>03676
          Length = 2457

 Score = 56.6 bits (135), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 46/180 (25%), Positives = 83/180 (46%), Gaps = 9/180 (5%)
 Frame = +2

Query: 121 SPIYMVKTHLQAQ-----AASEIAVGHQYKHQGMFQALTEIGQKHGLVGLWRGAVGGLPR 175
           +PI++ KT L  Q     + + + V H  +++G   A T+I ++ G+ GL++G V G+  
Sbjct: 680 NPIWVTKTRLCLQYEGYASTTTVPVSHA-QYRGTIDAFTKIFREEGVRGLYKGFVPGMLG 856

Query: 176 VVIGSSTQLCTFSSIKDLLSQWEIFPPQSWKVA----LAAAMVSGVAIVVAMTPFDVAST 231
           +  G+  Q   +  +K L +Q+   P  + K+     +  A VS +       P+ V  +
Sbjct: 857 ISHGA-LQFMAYEEMKTLYNQYRKQPLDT-KLGSGEYVTFAAVSKMFSACLTYPYQVIRS 1030

Query: 232 RLYNQPTDTRGKGLMYRGILDALLQTARTEGFFGMYKGIGASYFRLGPHTILSLFFWDQL 291
           RL +Q          Y G++D   Q  R E + G YKG  A    + P+  +    ++ L
Sbjct: 1031RLQDQHRH-------YNGVIDVCQQIIRKESYRGFYKGFTAYMLHVTPNICIVFLIYELL 1189

 Score = 38.5 bits (88), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 25/72 (34%), Positives = 33/72 (45%), Gaps = 4/72 (5%)
 Frame = +2

Query: 4   LMSGVAACGACVFTNPLEVVKTRMQLQGELQAPGTY----QRHYRNVFHAFFTIGKVDGL 59
            ++  A     V TNP+ V KTR+ LQ E  A  T        YR    AF  I + +G+
Sbjct: 638 FIASTAGFATLVLTNPIWVTKTRLCLQYEGYASTTTVPVSHAQYRGTIDAFTKIFREEGV 817

Query: 60  AALQKGLGPALL 71
             L KG  P +L
Sbjct: 818 RGLYKGFVPGML 853

 Score = 29.3 bits (64), Expect = 2.0,   Method: Compositional matrix adjust.
 Identities = 17/63 (26%), Positives = 30/63 (47%), Gaps = 1/63 (1%)
 Frame = +1

Query: 209 LAAAMVSGVAIVVAMTPFDVASTRL-YNQPTDTRGKGLMYRGILDALLQTARTEGFFGMY 267
           L A +  GV   + + P ++   R   N+   + G+   Y+GI  A+       GF G+Y
Sbjct: 331 LYAGVSGGVVSTLVLHPLELVKVRFQVNEGNGSSGR-PAYQGIGHAMRSIFNNRGFVGLY 507

Query: 268 KGI 270
           +G+
Sbjct: 508 QGV 516
>00831
          Length = 2468

 Score = 56.2 bits (134), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 38/136 (27%), Positives = 62/136 (45%)
 Frame = -2

Query: 157  GQKHGLVGLWRGAVGGLPRVVIGSSTQLCTFSSIKDLLSQWEIFPPQSWKVALAAAMVSG 216
            G+  G   ++ GA     R V+ +  QL  +  IK L+ +  I           + M   
Sbjct: 2467 GEGGGTHKVFNGATMASSRAVLVTIGQLACYDQIKALVLKTGILEDNIVLHLTCSTMAGT 2288

Query: 217  VAIVVAMTPFDVASTRLYNQPTDTRGKGLMYRGILDALLQTARTEGFFGMYKGIGASYFR 276
            +A  + M P DV  TR+ N    T      Y  ++   +  A+  G  G +KG   ++ R
Sbjct: 2287 IATFLTM-PLDVMKTRMMNAAPGT------YTSLMHCAMDIAK-NGPMGFFKGFIPAFVR 2132

Query: 277  LGPHTILSLFFWDQLR 292
            LGPHT+L+  F++Q+R
Sbjct: 2131 LGPHTVLTFVFFEQIR 2084

 Score = 28.1 bits (61), Expect = 4.7,   Method: Compositional matrix adjust.
 Identities = 24/66 (36%), Positives = 31/66 (46%)
 Frame = -2

Query: 6    SGVAACGACVFTNPLEVVKTRMQLQGELQAPGTYQRHYRNVFHAFFTIGKVDGLAALQKG 65
            S +A   A   T PL+V+KTRM       APGTY     ++ H    I K +G     KG
Sbjct: 2305 STMAGTIATFLTMPLDVMKTRMM----NAAPGTYT----SLMHCAMDIAK-NGPMGFFKG 2153

Query: 66   LGPALL 71
              PA +
Sbjct: 2152 FIPAFV 2135
>07963
          Length = 1390

 Score = 55.1 bits (131), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 68/298 (22%), Positives = 111/298 (37%), Gaps = 5/298 (1%)
 Frame = -1

Query: 4    LMSGVAACGACVFTNPLEVVKTRMQLQGELQAPGTYQRHYRNVFHAFFTIGKVDGLAALQ 63
            L  G+        T P E VKT++QL    +  G  Q+ Y   +H         G+  L 
Sbjct: 1282 LAGGITGGLEICITFPTEYVKTQLQLD---ERSGV-QKRYTGPWHCVTATVNEHGVRGLY 1115

Query: 64   KGLGPALLYQFLMNGIRLGTYGLAESRGYLHTNEGTHSPV-RSXXXXXXXXXXXXXXXSP 122
            +GL   L      + +R G +   E + +L   +G   P  R                +P
Sbjct: 1114 RGLSVLLYGSIPKSAVRFGAF--EEFKKHLVGADGVLDPHHRLLCGLGAGVMEAIFAVTP 941

Query: 123  IYMVKTHLQAQAASEIAVGHQYKHQGMFQALTEIGQKHGLVGLWRGAVGGLPRVVIGSST 182
            +  VK        S      +  ++G F  +++I ++ GL G+++G     P ++   S 
Sbjct: 940  METVKVKFINDQTSA-----KPHYRGFFHGVSQIVKEQGLHGVYQGLT---PTIIKQGSN 785

Query: 183  QLCTFSSIKDLLSQWEIFPPQSWKVALAAA----MVSGVAIVVAMTPFDVASTRLYNQPT 238
            Q   F  + + L  W     +  +V           +G A V   TP DV  TRL  Q  
Sbjct: 784  QAIRFF-VMETLKDWYRGDDKEMRVPTLIVGLFGATAGAASVFGNTPVDVVKTRL--QGL 614

Query: 239  DTRGKGLMYRGILDALLQTARTEGFFGMYKGIGASYFRLGPHTILSLFFWDQLRSFYN 296
            D       Y+  LD  ++  + EG    YKG      R+     ++   +D    F+N
Sbjct: 613  DAH----KYKNTLDCAMKIFKHEGPKAFYKGTVPRLSRVTLDVAITFMIYDNFMHFFN 452
>06435
          Length = 1099

 Score = 48.1 bits (113), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 36/141 (25%), Positives = 59/141 (41%), Gaps = 3/141 (2%)
 Frame = +1

Query: 158 QKHGLVGLWRGAVGGLPRVVIGSSTQLCTFSSIKDLLSQWEI---FPPQSWKVALAAAMV 214
           +  G   LWRG    + R+V  ++ Q C     K +L+        PP   +  LA +M 
Sbjct: 124 RTEGFFALWRGNTATMARIVPYAAIQYCAHEQYKIILNPNHXKKHLPPG--RRFLAGSM- 294

Query: 215 SGVAIVVAMTPFDVASTRLYNQPTDTRGKGLMYRGILDALLQTARTEGFFGMYKGIGASY 274
           +GV  V    P D+   R+     D      MY  I +  L+  R EG   +Y+G   + 
Sbjct: 295 AGVTSVAFTYPLDLVRARMAVTAKD------MYHNIFEVFLKIYREEGLRTVYRGFTPTI 456

Query: 275 FRLGPHTILSLFFWDQLRSFY 295
               P++  S F ++ L+  +
Sbjct: 457 LGSIPYSGTSFFTYETLKKLH 519

 Score = 30.0 bits (66), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 20/83 (24%), Positives = 38/83 (45%)
 Frame = +1

Query: 214 VSGVAIVVAMTPFDVASTRLYNQPTDTRGKGLMYRGILDALLQTARTEGFFGMYKGIGAS 273
           ++G      + P D   T++  Q  +T      ++  L  L  + RTEGFF +++G  A+
Sbjct: 4   LAGATAKTVIAPLD--RTKINFQIANT---PFSFKSALRFLYHSLRTEGFFALWRGNTAT 168

Query: 274 YFRLGPHTILSLFFWDQLRSFYN 296
             R+ P+  +     +Q +   N
Sbjct: 169 MARIVPYAAIQYCAHEQYKIILN 237
>06258
          Length = 1005

 Score = 46.6 bits (109), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 40/136 (29%), Positives = 62/136 (45%), Gaps = 1/136 (0%)
 Frame = +1

Query: 161 GLVGLWRGAVGGLPRVVIGSSTQLCTFSSIKDLLSQWEIFPPQSWKVALAAAMVSGVAIV 220
           G  GL++GA   L R V  S+     ++  K   +    +   S    L +A ++G+   
Sbjct: 52  GFFGLYKGARACLLRDVPFSAIYFPAYAHNKKYFADENGY--NSPGTLLLSATIAGMPAA 225

Query: 221 VAMTPFDVASTRLYNQPTDTRGKGLMYRGILDALLQTARTEGFFGMYKGIGASYFRLGPH 280
              TP DV  TRL  Q  +  G+   Y+GI+D   +  + EG    +KG  A  FR  P 
Sbjct: 226 FFPTPADVIKTRL--QVAERAGQ-TTYKGIMDCCRKITQEEGLAAFWKGSAARVFRSSPQ 396

Query: 281 TILSLFFWDQL-RSFY 295
             ++L  ++ L R FY
Sbjct: 397 FGVTLLTYELLQRLFY 444
>13320
          Length = 1694

 Score = 45.8 bits (107), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 26/77 (33%), Positives = 38/77 (49%), Gaps = 7/77 (9%)
 Frame = -2

Query: 226  FDVASTRLYNQ-----PTDTRGKGL--MYRGILDALLQTARTEGFFGMYKGIGASYFRLG 278
            F +  TR+ NQ     PT      +  +Y   LD L QT +TEG   +YKG   ++ RLG
Sbjct: 1666 FGLLQTRMMNQKKLISPTAAPSGAVQVVYSSSLDCLAQTVKTEGVMALYKGFIPNWLRLG 1487

Query: 279  PHTILSLFFWDQLRSFY 295
            P  I+    ++ L+  Y
Sbjct: 1486 PWNIIFFMTYEHLKKTY 1436
>11720
          Length = 504

 Score = 45.4 bits (106), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 26/70 (37%), Positives = 37/70 (52%), Gaps = 1/70 (1%)
 Frame = +1

Query: 3   FLMSGVAACGACVFTNPLEVVKTRMQLQGELQAPGTY-QRHYRNVFHAFFTIGKVDGLAA 61
            L++  A       TNP+ V KTR+ LQ E +A  +  +R YR +  A   I KV+G+  
Sbjct: 292 MLIASAAGFSTLALTNPIWVTKTRLCLQYESEAAASKAERQYRGMADALVKIYKVEGVRG 471

Query: 62  LQKGLGPALL 71
           L KG  P +L
Sbjct: 472 LYKGFIPGIL 501

 Score = 38.9 bits (89), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 36/151 (23%), Positives = 59/151 (39%), Gaps = 3/151 (1%)
 Frame = +1

Query: 122 PIYMVKTHLQAQAASEIAVGHQYKHQGMFQALTEIGQKHGLVGLWRGAVGGLPRVVIGSS 181
           P+ +VK   Q       A    Y+  G+  A+  I    GL GL++G    +    +   
Sbjct: 37  PLDLVKIRFQVNEGHGTAGRPAYR--GIVHAMRSIVANSGLXGLYQGVTPNVWGAGLSWG 210

Query: 182 TQLCTFSSIKDLLSQWEIFPPQSWKVALAAAMVSGVAIVVAMTPFDVASTRL---YNQPT 238
                ++S+K  +   +          +  A  +G + +    P  V  TRL   Y    
Sbjct: 211 LYFFFYNSMKTWMQDGDGKKNLGATNHMLIASAAGFSTLALTNPIWVTKTRLCLQYESEA 390

Query: 239 DTRGKGLMYRGILDALLQTARTEGFFGMYKG 269
                   YRG+ DAL++  + EG  G+YKG
Sbjct: 391 AASKAERQYRGMADALVKIYKVEGVRGLYKG 483

 Score = 35.4 bits (80), Expect = 0.030,   Method: Compositional matrix adjust.
 Identities = 21/80 (26%), Positives = 39/80 (48%), Gaps = 1/80 (1%)
 Frame = +1

Query: 216 GVAIVVAMTPFDVASTRL-YNQPTDTRGKGLMYRGILDALLQTARTEGFFGMYKGIGASY 274
           GV   + + P D+   R   N+   T G+   YRGI+ A+       G  G+Y+G+  + 
Sbjct: 10  GVVSTLVLHPLDLVKIRFQVNEGHGTAGR-PAYRGIVHAMRSIVANSGLXGLYQGVTPNV 186

Query: 275 FRLGPHTILSLFFWDQLRSF 294
           +  G    L  FF++ ++++
Sbjct: 187 WGAGLSWGLYFFFYNSMKTW 246
>17936
          Length = 447

 Score = 43.9 bits (102), Expect = 9e-05,   Method: Compositional matrix adjust.
 Identities = 21/69 (30%), Positives = 32/69 (46%)
 Frame = -1

Query: 225 PFDVASTRLYNQPTDTRGKGLMYRGILDALLQTARTEGFFGMYKGIGASYFRLGPHTILS 284
           P D+  TR+ NQ T +    LMY+   D   +  R EG  G+Y+G+      + P   + 
Sbjct: 243 PIDLVKTRMQNQRTGSYVGELMYKNSFDCFKKVIRHEGVRGLYRGLAPQLVGVAPEKAIK 64

Query: 285 LFFWDQLRS 293
           L   D +R 
Sbjct: 63  LTMNDLMRD 37

 Score = 35.4 bits (80), Expect = 0.028,   Method: Compositional matrix adjust.
 Identities = 27/83 (32%), Positives = 41/83 (49%), Gaps = 2/83 (2%)
 Frame = -1

Query: 19  PLEVVKTRMQLQGELQAPGTY--QRHYRNVFHAFFTIGKVDGLAALQKGLGPALLYQFLM 76
           P+++VKTRMQ     Q  G+Y  +  Y+N F  F  + + +G+  L +GL P L+     
Sbjct: 243 PIDLVKTRMQ----NQRTGSYVGELMYKNSFDCFKKVIRHEGVRGLYRGLAPQLVGVAPE 76

Query: 77  NGIRLGTYGLAESRGYLHTNEGT 99
             I+L    L   R  L   +GT
Sbjct: 75  KAIKLTMNDLM--RDKLVRKDGT 13
>13322
          Length = 1014

 Score = 42.4 bits (98), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 22/64 (34%), Positives = 33/64 (51%)
 Frame = -1

Query: 2   DFLMSGVAACGACVFTNPLEVVKTRMQLQGELQAPGTYQRHYRNVFHAFFTIGKVDGLAA 61
            F+   +A C A    NP++VVKTR+Q   +    G  ++HY  + H F T+   +G  A
Sbjct: 489 SFISGCIAGCTASFLVNPMDVVKTRLQTLHK----GAGEQHYTGIVHCFRTVMTQEGPKA 322

Query: 62  LQKG 65
             KG
Sbjct: 321 FLKG 310

 Score = 40.8 bits (94), Expect = 6e-04,   Method: Compositional matrix adjust.
 Identities = 19/46 (41%), Positives = 25/46 (54%)
 Frame = -1

Query: 247  YRGILDALLQTARTEGFFGMYKGIGASYFRLGPHTILSLFFWDQLR 292
            Y+ + D  L+T R EGFFGMYKG G +   + P   + L   D  R
Sbjct: 1014 YKSLPDCALKTFRNEGFFGMYKGSGVNLLLITPEKAIKLVGNDFFR 877
>11735
          Length = 1194

 Score = 40.8 bits (94), Expect = 8e-04,   Method: Compositional matrix adjust.
 Identities = 26/89 (29%), Positives = 39/89 (43%), Gaps = 4/89 (4%)
 Frame = +2

Query: 16  FTNPLEVVKTRMQLQGELQAPGTYQRHYRNVFHAFFTIGKVDGLAALQKGLGPALLYQFL 75
             NP +V+K RMQ  G        Q    N+  +F  I   +G+A L +G+GP      +
Sbjct: 17  IANPTDVLKIRMQATGA-------QTKCDNMLCSFVKIYNTEGVAGLWRGVGPTAQRAAV 175

Query: 76  MNGIRLGTYGLAESR----GYLHTNEGTH 100
           + G+ L  Y L +      G L   + TH
Sbjct: 176 VAGVELPAYDLCKKHILRSGLLGDTKETH 262
>00983
          Length = 819

 Score = 39.3 bits (90), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 38/159 (23%), Positives = 68/159 (42%), Gaps = 4/159 (2%)
 Frame = -2

Query: 146 HQGMFQALTEIGQKHGLVGLWRGAVGGLPRVVIGSSTQLCTFSSIKDLLSQWEIFPPQSW 205
           ++G    +++I ++ GL G+++G     P ++   S Q   F  + + + +W     ++ 
Sbjct: 809 YRGFAHGISQIIKEQGLHGVYQGVA---PTIMKQGSNQAIRFF-VMETMKEWYRGDDKNK 642

Query: 206 KV----ALAAAMVSGVAIVVAMTPFDVASTRLYNQPTDTRGKGLMYRGILDALLQTARTE 261
           KV      A    +G A V   TP DV  TRL  Q  D       Y+G +D  ++  + E
Sbjct: 641 KVPTLLTGAFGATAGAASVFGNTPIDVVKTRL--QGLDAHK----YKGTIDCAVKIMKNE 480

Query: 262 GFFGMYKGIGASYFRLGPHTILSLFFWDQLRSFYNTYAK 300
           G    YKG      R+     ++   +D     +N + K
Sbjct: 479 GPRAFYKGTLPRLSRVTLDVAITFMIYDNFMHIFNQFWK 363

 Score = 33.1 bits (74), Expect = 0.13,   Method: Compositional matrix adjust.
 Identities = 12/52 (23%), Positives = 27/52 (51%)
 Frame = -2

Query: 244 GLMYRGILDALLQTARTEGFFGMYKGIGASYFRLGPHTILSLFFWDQLRSFY 295
           G +YRG    + Q  + +G  G+Y+G+  +  + G +  +  F  + ++ +Y
Sbjct: 818 GPIYRGFAHGISQIIKEQGLHGVYQGVAPTIMKQGSNQAIRFFVMETMKEWY 663
>03275
          Length = 3821

 Score = 38.1 bits (87), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 41/174 (23%), Positives = 75/174 (43%), Gaps = 4/174 (2%)
 Frame = +1

Query: 122  PIYMVKTHLQAQAASEIAVGHQYKHQGMFQALTEIGQKHGLVGLWRGAVGGLPRVVIGSS 181
            PI ++KT L++ +         +++QGM  ALT I ++ G+ GL+ G    L R V  S 
Sbjct: 3214 PITVIKTRLESGS---------FQYQGMANALTLIYKREGIRGLYSGLSPTLLRDVPFSG 3366

Query: 182  TQLCTFSSIKDLLSQWEI----FPPQSWKVALAAAMVSGVAIVVAMTPFDVASTRLYNQP 237
              L  +S +K + +Q  +    F P    V    A++ G        P DV  T +   P
Sbjct: 3367 LYLMFYSKLK-MYNQPSMFGCGFEPL---VDFCNAVIGGALASFVTQPADVIKTNMQLYP 3534

Query: 238  TDTRGKGLMYRGILDALLQTARTEGFFGMYKGIGASYFRLGPHTILSLFFWDQL 291
                     +R +   ++   +  G +G ++G+     R    T L+   ++++
Sbjct: 3535 RQ-------HRHLKQVIVYVYQKRGMYGFWRGMVPRTLRRTTMTALAWTVFEEI 3675

 Score = 33.5 bits (75), Expect = 0.10,   Method: Compositional matrix adjust.
 Identities = 22/86 (25%), Positives = 36/86 (41%)
 Frame = +1

Query: 209  LAAAMVSGVAIVVAMTPFDVASTRLYNQPTDTRGKGLMYRGILDALLQTARTEGFFGMYK 268
            L   M +       + P  V  TRL             Y+G+ +AL    + EG  G+Y 
Sbjct: 3166 LGMGMTARTMAACLILPITVIKTRL-------ESGSFQYQGMANALTLIYKREGIRGLYS 3324

Query: 269  GIGASYFRLGPHTILSLFFWDQLRSF 294
            G+  +  R  P + L L F+ +L+ +
Sbjct: 3325 GLSPTLLRDVPFSGLYLMFYSKLKMY 3402

 Score = 33.1 bits (74), Expect = 0.12,   Method: Compositional matrix adjust.
 Identities = 22/85 (25%), Positives = 36/85 (42%), Gaps = 6/85 (7%)
 Frame = +3

Query: 201  PPQSWK------VALAAAMVSGVAIVVAMTPFDVASTRLYNQPTDTRGKGLMYRGILDAL 254
            PP+S K      VA+ A  +SG    + + P D+  TRL +        G+     ++  
Sbjct: 2838 PPRSLKQWYQRRVAITAGAMSGSMSTLLLQPLDLVKTRLQSSVHFESNIGM-----VNVA 3002

Query: 255  LQTARTEGFFGMYKGIGASYFRLGP 279
            +   R E F  ++ G+  S  R  P
Sbjct: 3003 VSVVRQEKFLALWNGVWPSLTRCAP 3077

 Score = 29.6 bits (65), Expect = 1.7,   Method: Compositional matrix adjust.
 Identities = 19/79 (24%), Positives = 34/79 (43%)
 Frame = +1

Query: 1    MDFLMSGVAACGACVFTNPLEVVKTRMQLQGELQAPGTYQRHYRNVFHAFFTIGKVDGLA 60
            +DF  + +    A   T P +V+KT MQL         Y R +R++      + +  G+ 
Sbjct: 3442 VDFCNAVIGGALASFVTQPADVIKTNMQL---------YPRQHRHLKQVIVYVYQKRGMY 3594

Query: 61   ALQKGLGPALLYQFLMNGI 79
               +G+ P  L +  M  +
Sbjct: 3595 GFWRGMVPRTLRRTTMTAL 3651
>11205
          Length = 883

 Score = 37.0 bits (84), Expect = 0.011,   Method: Compositional matrix adjust.
 Identities = 40/166 (24%), Positives = 59/166 (35%), Gaps = 4/166 (2%)
 Frame = -1

Query: 7   GVAACGACVF----TNPLEVVKTRMQLQGELQAPGTYQRHYRNVFHAFFTIGKVDGLAAL 62
           GVA C A V      NP +VVK RMQ+ G           YR       +I + +G+ A 
Sbjct: 880 GVAGCAATVLHDAVMNPADVVKQRMQVYGS---------GYRTSLQCVSSILQKEGVWAF 728

Query: 63  QKGLGPALLYQFLMNGIRLGTYGLAESRGYLHTNEGTHSPVRSXXXXXXXXXXXXXXXSP 122
            +     LL        +   Y + +    +   +  ++PV                  P
Sbjct: 727 YRSYTTQLLMNVPFQSTQFVIYEIMQD---VLNKDRAYNPVTHMCSGAVAGAVAASITMP 557

Query: 123 IYMVKTHLQAQAASEIAVGHQYKHQGMFQALTEIGQKHGLVGLWRG 168
           + + KT L  Q     A  +     GMF A   I +  G  G +RG
Sbjct: 556 LDVCKTLLNTQETC--ARTNLTYINGMFSAFRTIYEFRGSHGFFRG 425
>05312
          Length = 1032

 Score = 35.0 bits (79), Expect = 0.034,   Method: Compositional matrix adjust.
 Identities = 27/65 (41%), Positives = 30/65 (46%), Gaps = 1/65 (1%)
 Frame = -3

Query: 7   GVAACGACVFTN-PLEVVKTRMQLQGELQAPGTYQRHYRNVFHAFFTIGKVDGLAALQKG 65
           G  A  A VF N PL+VVKTRMQ        G     Y+N       I K +GL A  KG
Sbjct: 466 GAIAGAASVFGNTPLDVVKTRMQ--------GLEAARYKNTADCAMQILKNEGLPAFYKG 311

Query: 66  LGPAL 70
             P L
Sbjct: 310 TVPRL 296

 Score = 32.3 bits (72), Expect = 0.23,   Method: Compositional matrix adjust.
 Identities = 28/132 (21%), Positives = 58/132 (43%), Gaps = 9/132 (6%)
 Frame = -2

Query: 158 QKHGLVGLWRGAV----GGLPRVVIGSSTQLCTFSSIKDLLSQWEIFPPQSWKVALAAAM 213
           ++ G  GL+RG      G +P+    S+ +   F    + L    + P  S +++ +  +
Sbjct: 917 KERGFFGLYRGLSVLLYGSIPK----SAARFGAF----EFLRSKAVGP--SGQLSNSGKL 768

Query: 214 VSGVAI-----VVAMTPFDVASTRLYNQPTDTRGKGLMYRGILDALLQTARTEGFFGMYK 268
           + G+       +VA+TP +    +  N   D R     ++G    + +  + EG  G+YK
Sbjct: 767 LCGLGAGICEAIVAVTPMETIKVKFIN---DQRSANPKFKGFAHGVKEIVKAEGISGIYK 597

Query: 269 GIGASYFRLGPH 280
           G+  +  + G +
Sbjct: 596 GLTPTIMKQGSN 561
>23802
          Length = 1077

 Score = 35.0 bits (79), Expect = 0.036,   Method: Compositional matrix adjust.
 Identities = 24/82 (29%), Positives = 34/82 (41%)
 Frame = +2

Query: 215 SGVAIVVAMTPFDVASTRLYNQPTDTRGKGLMYRGILDALLQTARTEGFFGMYKGIGASY 274
           +G A V   TP DV  TRL  Q  D       Y+  LD  ++  + EG    YKG     
Sbjct: 32  AGAASVFGNTPVDVVKTRL--QGLDAHK----YKNTLDCAMKIFKHEGPKAFYKGTVPRL 193

Query: 275 FRLGPHTILSLFFWDQLRSFYN 296
            R+     ++   +D    F+N
Sbjct: 194 SRVTLDVAITFMIYDNFMHFFN 259
>13140
          Length = 1844

 Score = 33.5 bits (75), Expect = 0.12,   Method: Compositional matrix adjust.
 Identities = 25/86 (29%), Positives = 38/86 (44%)
 Frame = -2

Query: 207 VALAAAMVSGVAIVVAMTPFDVASTRLYNQPTDTRGKGLMYRGILDALLQTARTEGFFGM 266
           V  AA  ++GV   +   P D   ++L NQ      KG          +Q A+  GF GM
Sbjct: 838 VTFAAGYIAGVFCAIVSHPADTIVSKL-NQ-----AKG-------SNFVQIAKQLGFMGM 698

Query: 267 YKGIGASYFRLGPHTILSLFFWDQLR 292
           +KG+      +G  T L  F +D ++
Sbjct: 697 WKGLFPRIIMIGTLTALQWFIYDSVK 620
>31492
          Length = 448

 Score = 33.5 bits (75), Expect = 0.12,   Method: Compositional matrix adjust.
 Identities = 22/66 (33%), Positives = 34/66 (51%), Gaps = 3/66 (4%)
 Frame = +2

Query: 202 PQSWKVALAAAMVSGVAIVVAMTPFDVASTRLYNQPTDTRGKG---LMYRGILDALLQTA 258
           P   +VAL A  ++G ++ V + P D   TRL +Q    RG G    +Y G++ A L +A
Sbjct: 14  PVDIRVALLAGGIAGTSVDVVLFPLDTIKTRLQSQ-QGLRGSGGFRGVYSGLMSAALGSA 190

Query: 259 RTEGFF 264
            +   F
Sbjct: 191 PSGALF 208

 Score = 28.5 bits (62), Expect = 3.1,   Method: Compositional matrix adjust.
 Identities = 15/47 (31%), Positives = 23/47 (48%)
 Frame = +2

Query: 3  FLMSGVAACGACVFTNPLEVVKTRMQLQGELQAPGTYQRHYRNVFHA 49
           L  G+A     V   PL+ +KTR+Q Q  L+  G ++  Y  +  A
Sbjct: 35 LLAGGIAGTSVDVVLFPLDTIKTRLQSQQGLRGSGGFRGVYSGLMSA 175
>03571
          Length = 1155

 Score = 33.1 bits (74), Expect = 0.15,   Method: Compositional matrix adjust.
 Identities = 21/72 (29%), Positives = 32/72 (44%), Gaps = 6/72 (8%)
 Frame = +3

Query: 224 TPFDVASTRLYNQ------PTDTRGKGLMYRGILDALLQTARTEGFFGMYKGIGASYFRL 277
           TP DV    L +Q      PT    +   Y+G L+A  +  RT G  GM++G      R 
Sbjct: 327 TPIDVVKVTLQSQIEHEICPTTGVHQSTFYKGPLEATKEIFRTCGARGMFRGFWTQLARD 506

Query: 278 GPHTILSLFFWD 289
            P   + + F++
Sbjct: 507 SPANAVYMSFYE 542
>18662
          Length = 551

 Score = 31.2 bits (69), Expect = 0.60,   Method: Compositional matrix adjust.
 Identities = 19/56 (33%), Positives = 31/56 (55%)
 Frame = +1

Query: 122 PIYMVKTHLQAQAASEIAVGHQYKHQGMFQALTEIGQKHGLVGLWRGAVGGLPRVV 177
           PI ++KT L++ +         +++QGM  ALT I ++ G+ GL+ G    L R V
Sbjct: 406 PITVIKTRLESGS---------FQYQGMANALTLIYKREGIRGLYSGLSPTLLRDV 546
>24291
          Length = 1025

 Score = 27.7 bits (60), Expect = 5.3,   Method: Compositional matrix adjust.
 Identities = 23/80 (28%), Positives = 31/80 (38%)
 Frame = +2

Query: 166 WRGAVGGLPRVVIGSSTQLCTFSSIKDLLSQWEIFPPQSWKVALAAAMVSGVAIVVAMTP 225
           W G V   P+    +S   C             IFP  S  V L     S +A+V    P
Sbjct: 164 WEGLVTPFPQ---SNSLXFC-------------IFPKPSQPVKL*PRQQSALALVSQSVP 295

Query: 226 FDVASTRLYNQPTDTRGKGL 245
             V  TR  ++P+D   +GL
Sbjct: 296 HTVHGTRSISRPSDATLQGL 355
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31711990|ref|NP_766535.1| LSM12 homolog [Mus
musculus]
         (195 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

36534                                                                  73   8e-14
01198                                                                  27   4.3  
15387                                                                  27   4.4  
>36534
          Length = 698

 Score = 72.8 bits (177), Expect = 8e-14,   Method: Compositional matrix adjust.
 Identities = 41/96 (42%), Positives = 57/96 (59%), Gaps = 7/96 (7%)
 Frame = +2

Query: 88  ASKARTEKEEKLSQAYAISAGVSLEGQQLFQTIHKTIKDCKWQEKNIVVMEEVVITPPYQ 147
            ++ R    E+  Q   +   VS EGQQL  TI KTI D KW+ +NI+VM+ V+ITPPY 
Sbjct: 2   TNRTRQNITERKRQWNYVGENVSAEGQQLMDTISKTITDVKWESENIIVMDCVLITPPYT 181

Query: 148 VENCK---GKE----GSALSHVRKIVEKHFRDVESQ 176
           V +     GKE     + L+H+RK+VEK  +D  S+
Sbjct: 182 VSHLSLLPGKEQQQNQTTLNHLRKMVEKXQQDERSR 289
>01198
          Length = 3401

 Score = 27.3 bits (59), Expect = 4.3,   Method: Compositional matrix adjust.
 Identities = 10/25 (40%), Positives = 16/25 (64%)
 Frame = -1

Query: 154 KEGSALSHVRKIVEKHFRDVESQKI 178
           +EG+ ++H   I  KH  D+E+ KI
Sbjct: 770 EEGTKVNHFNDIYSKHIPDIENDKI 696
>15387
          Length = 884

 Score = 27.3 bits (59), Expect = 4.4,   Method: Compositional matrix adjust.
 Identities = 10/25 (40%), Positives = 16/25 (64%)
 Frame = +1

Query: 154 KEGSALSHVRKIVEKHFRDVESQKI 178
           +EG+ ++H   I  KH  D+E+ KI
Sbjct: 94  EEGTKVNHFNDIYSKHIPDIENDKI 168
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|144922638|ref|NP_032503.2| kinectin 1 [Mus musculus]
         (1327 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

15632                                                                  75   1e-13
19049                                                                  56   3e-11
07293                                                                  32   2.2  
09439                                                                  30   4.7  
>15632
          Length = 633

 Score = 75.5 bits (184), Expect = 1e-13,   Method: Compositional matrix adjust.
 Identities = 49/127 (38%), Positives = 76/127 (59%), Gaps = 4/127 (3%)
 Frame = -1

Query: 994  LKNAVEHQRKKNNDLREKNWEAMEALASTEKMLQDRVNKTSKERRQ----HVEAIELESK 1049
            LK  ++ Q++KNN+LREKNW+AMEAL   + + Q ++ K+ K  R+     V  +E   K
Sbjct: 414  LKTQLDAQKQKNNELREKNWKAMEALEKLKSLQQKKLIKSLKASRETTTKAVTEVEKADK 235

Query: 1050 DLLKRLFPTVSVPSNLNYSEWLRGFEKKAKACVAGTSDAEAVKVLEHRLKEASEMHTLLQ 1109
            + LKRLFP +SV   L + EWL  FEK+A   +  +S +E  K +  +L +  E ++ LQ
Sbjct: 234  EALKRLFPALSVSDKLGHKEWLATFEKQAAQQLTQSSKSE--KSVSDKLGQLEEENSRLQ 61

Query: 1110 LECEKYK 1116
             + E +K
Sbjct: 60   ADVEVFK 40
>19049
          Length = 963

 Score = 56.2 bits (134), Expect(2) = 3e-11,   Method: Compositional matrix adjust.
 Identities = 32/68 (47%), Positives = 45/68 (66%), Gaps = 4/68 (5%)
 Frame = -1

Query: 994  LKNAVEHQRKKNNDLREKNWEAMEALASTEKMLQDRVNKTSKERRQ----HVEAIELESK 1049
            LK  ++ Q++KNN+LREKNW+AMEAL  TEK   ++V+K+ K  R+     V  +E   K
Sbjct: 420  LKTQLDAQKQKNNELREKNWKAMEALEKTEKSAAEKVDKSLKASRETTTKAVTEVEKADK 241

Query: 1050 DLLKRLFP 1057
            + LKRL P
Sbjct: 240  EALKRLXP 217

 Score = 31.2 bits (69), Expect(2) = 3e-11,   Method: Compositional matrix adjust.
 Identities = 21/64 (32%), Positives = 36/64 (56%)
 Frame = -2

Query: 1057 PTVSVPSNLNYSEWLRGFEKKAKACVAGTSDAEAVKVLEHRLKEASEMHTLLQLECEKYK 1116
            P +SV   L + EWL  FEK+A   +  +S +E  K +  +L +  E ++ LQ + E +K
Sbjct: 218  PALSVSDKLGHKEWLATFEKQAAQQLTQSSKSE--KSVSDKLGQLEEENSRLQADVEVFK 45

Query: 1117 SVLA 1120
            + +A
Sbjct: 44   NNIA 33
>07293
          Length = 3312

 Score = 31.6 bits (70), Expect = 2.2,   Method: Compositional matrix adjust.
 Identities = 21/60 (35%), Positives = 35/60 (58%), Gaps = 4/60 (6%)
 Frame = -3

Query: 485  AATQLKVQLQEA----ERRWEEVQSYIRKRTAEHEAAQQDLQSKFVAKENEVQSLHSKLT 540
            A+TQL+ +LQ A    ++ W+E    +R++  +H+AA   LQS+F   +  VQ L +  T
Sbjct: 3259 ASTQLQTELQTALHKSQQVWQEHVDCLRQQVDQHDAA---LQSQFDHLQGAVQQLSADCT 3089
>09439
          Length = 1665

 Score = 30.4 bits (67), Expect = 4.7,   Method: Compositional matrix adjust.
 Identities = 21/45 (46%), Positives = 28/45 (62%), Gaps = 1/45 (2%)
 Frame = +1

Query: 910 ELESVLK-EKDNEIKRIEVKLKDTESDVSKMSELLKEVQEENKFL 953
           E E+ LK EK NEIK+I   +   +S++SK  + LKE Q   KFL
Sbjct: 358 EAEAKLKMEKVNEIKKINAMMMAIKSEISKYEDTLKEYQHYKKFL 492
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|21704190|ref|NP_663570.1| carbonic reductase 4 [Mus
musculus]
         (236 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

12758                                                                  72   1e-13
20818                                                                  62   3e-10
28229                                                                  40   6e-09
00991                                                                  56   1e-08
03060                                                                  54   5e-08
03983                                                                  51   5e-07
01459                                                                  41   4e-04
18041                                                                  40   8e-04
21038                                                                  40   9e-04
18534                                                                  37   0.006
35662                                                                  37   0.009
36857                                                                  35   0.019
36378                                                                  34   0.041
27168                                                                  32   0.31 
23264                                                                  29   1.7  
>12758
          Length = 804

 Score = 72.4 bits (176), Expect = 1e-13,   Method: Compositional matrix adjust.
 Identities = 55/187 (29%), Positives = 85/187 (45%), Gaps = 11/187 (5%)
 Frame = -1

Query: 56  DVAKEQDVQSTFQEMEKHLGPVNFLVNAAGINRGSLLVRTKTEDMISQLHTNLLGSMLTC 115
           D+ KE D +   +E  K  G +N LVN AGI     +  T  +      +TN+       
Sbjct: 717 DLTKEDDTKRVVEETVKQFGRLNILVNCAGIIELGNIENTSLDQYDRMFNTNVRSVYHLT 538

Query: 116 KAAMKTMIQQXXXXXXXXXXXXLKGNVGQSAYSATKGGLVGFSRSLAKEVARKKIRVNVV 175
             A+  ++              ++      AY   K  +  F+R +A E+A KK+RVN V
Sbjct: 537 MLAVPHLVNTQGNIVNVSSVNGMRSFPNVLAYCMAKSAIDQFTRCVALELAPKKVRVNGV 358

Query: 176 APGFIRTDMTRH--LKEEHFKKNI-------PLGRFGETLEVAHAVVFLL--ESPYITGH 224
            PG I +++ +   L +E + K +        LGR G+  EVA  + FL   ++ +ITG 
Sbjct: 357 NPGVIISELQKRGGLDDEAYAKFLERSKETHALGRPGQPEEVARXIAFLASEDASFITGA 178

Query: 225 VLIVDGG 231
            L VDGG
Sbjct: 177 SLPVDGG 157
>20818
          Length = 613

 Score = 61.6 bits (148), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 38/93 (40%), Positives = 52/93 (55%), Gaps = 9/93 (9%)
 Frame = +1

Query: 151 KGGLVGFSRSLAKEVARKKIRVNVVAPG---FIRTDMTRHLKEEHFKKN---IPLGRFGE 204
           + G+   ++SL+ E A   +R+N VAPG   +  T    +   + F KN   +PL RFG 
Sbjct: 22  RAGVENLTKSLSIEWASDGVRINCVAPGSSIYSETAAANYGSLDIFSKNLESVPLNRFGT 201

Query: 205 TLEVAHAVVFLLESP---YITGHVLIVDGGLQL 234
           T EV+ AV FLL SP   +ITG  + VDGG  L
Sbjct: 202 TEEVSAAVCFLL-SPAAAFITGETIKVDGGSSL 297
>28229
          Length = 633

 Score = 40.0 bits (92), Expect(2) = 6e-09,   Method: Compositional matrix adjust.
 Identities = 32/103 (31%), Positives = 49/103 (47%), Gaps = 5/103 (4%)
 Frame = -2

Query: 11  SRGIGRAVAQLMAQKGYRLAIVSRNLE-----VAKVTAGELGGNHLAFRCDVAKEQDVQS 65
           S GIG A+AQ++A++G  L++V RN+         +     G   L    DV    D  +
Sbjct: 629 SSGIGVAIAQVLAREGAVLSLVGRNVTNLEATRTTLQQQTTGVQVLNVVADVTT--DSAA 456

Query: 66  TFQEMEKHLGPVNFLVNAAGINRGSLLVRTKTEDMISQLHTNL 108
             Q+   H G ++ LVN AGI     L+     +  + L+TNL
Sbjct: 455 IIQQTINHYGRIDVLVNNAGILGNGPLIDLDIAEFDAVLNTNL 327

 Score = 37.0 bits (84), Expect(2) = 6e-09,   Method: Compositional matrix adjust.
 Identities = 22/71 (30%), Positives = 39/71 (54%), Gaps = 9/71 (12%)
 Frame = -1

Query: 143 GQSAYSATKGGLVGFSRSLAKEVARKKIRVNVVAPGFIRTDMTRHLK--EEHFK------ 194
           G  +Y  +K  L  F++ ++ E+A + +RVN V PGF+ T++   +   +E +K      
Sbjct: 225 GALSYGISKAALDQFTKIVSLELAPQGVRVNSVNPGFVVTNIHSRIGIVDEAYKSLHERA 46

Query: 195 -KNIPLGRFGE 204
             + P+GR GE
Sbjct: 45  INSHPMGRVGE 13
>00991
          Length = 1146

 Score = 56.2 bits (134), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 50/193 (25%), Positives = 86/193 (44%), Gaps = 11/193 (5%)
 Frame = +2

Query: 48  GNHLAFRCDVAKEQDVQSTFQEMEKH---LGPVNFLVNAAGINRGSLLVRTKTEDMISQL 104
           G+  A RCDV+KE+DV + F  M +H   LG V+  +N AG+   + L+           
Sbjct: 455 GSLTAVRCDVSKEEDVSAMFH-MIRHNTSLGRVDVCINNAGLAHDAPLLTGDPAQWKHMF 631

Query: 105 HTNLLGSMLTCKAAMKTMIQQXXXXXXXXXXXXLKGN--VGQS---AYSATKGGLVGFSR 159
             N+LG M+  K A   M +             + G   + Q     Y+A+K  +     
Sbjct: 632 DVNVLGLMMVTKEAFTLMQENNIDDGHIVLVNSMSGKRVLNQKRTHCYAASKFAVTAIFE 811

Query: 160 SLAKEV--ARKKIRVNVVAPGFIRTDMT-RHLKEEHFKKNIPLGRFGETLEVAHAVVFLL 216
            L  E+   + KIR++ V PG + T    R + EE  K      +  +  ++  +++++L
Sbjct: 812 GLRNELRELKSKIRISQVCPGLVETQFAPRLMGEEGAKATYSGYKCLQAEDIRDSILYIL 991

Query: 217 ESPYITGHVLIVD 229
           ++P    HV + D
Sbjct: 992 DAP---PHVEVND 1021
>03060
          Length = 1893

 Score = 54.3 bits (129), Expect = 5e-08,   Method: Compositional matrix adjust.
 Identities = 49/196 (25%), Positives = 93/196 (47%), Gaps = 11/196 (5%)
 Frame = -1

Query: 3    KVCAVFGGSRGIGRAVAQLMAQKGYRLAIVSRNLEVAKVTAGELGGNHLAFR-CDVA--- 58
            KV  V G S G+G+A A++  Q G ++ +  R++E        L  +    + C+ +   
Sbjct: 1686 KVVLVTGASSGLGKACAKVFHQHGCQVILAGRSVERLNAVKDYLTKSEGEVKACEPSVLA 1507

Query: 59   -KEQDVQSTFQEMEKHL---GPVNFLVNAAGINRGSLLVRTKTEDMISQLHTNLLGSMLT 114
               +D+ S  Q  E+ +   G V+ ++N AGI+    +  T  +     +  N  G +  
Sbjct: 1506 MDLEDLNSLQQLAERAVELFGKVDVVINNAGISYRGCIEDTSIQVDQKLMAVNYFGHVAL 1327

Query: 115  CKAAMKTMIQQXXXXXXXXXXXXLKGNVG---QSAYSATKGGLVGFSRSLAKEVARKKIR 171
             K  +  M  Q            ++G +    +SAYSA+K  L  F   L  E++  KI+
Sbjct: 1326 IKGLLPHM--QARNSGHIVGISSVQGKISIPYRSAYSASKHALQAFFDCLRAELSCTKIK 1153

Query: 172  VNVVAPGFIRTDMTRH 187
            V++++PG+I+T+++ +
Sbjct: 1152 VSLLSPGYIKTNLSNN 1105
>03983
          Length = 1099

 Score = 50.8 bits (120), Expect = 5e-07,   Method: Compositional matrix adjust.
 Identities = 46/187 (24%), Positives = 76/187 (40%), Gaps = 6/187 (3%)
 Frame = +2

Query: 9   GGSRGIGRAVAQLMAQKGYRLAIVSRNLEVAKVTAGELGG--NHLAFRCDVAKEQDVQST 66
           G   G+G+ +A      G  L +   N E  +    ++G   +  A+  D++  + +   
Sbjct: 197 GAGSGLGKLMAYRFMGLGCDLVLWDINTEAIEAMERDMGQQVSCKAYTVDLSSREQIYKA 376

Query: 67  FQEMEKHLGPVNFLVNAAGINRGSLLVRTKTEDMISQLHTNLLGSMLTCKAAMKTMI-QQ 125
             ++++ +G V+ LVN AGI  G   +      +   +  N      T KA +  M+ Q 
Sbjct: 377 ADQVKREVGGVDILVNNAGIVTGRKFLDCPDSLIEKTMEVNSNAHFWTVKAFLPNMLAQN 556

Query: 126 XXXXXXXXXXXXLKGNVGQSAYSATKGGLVGFSRSLAKEV---ARKKIRVNVVAPGFIRT 182
                       L G  G + Y A+K   VGF  SL  E+    +  +   VV P FI T
Sbjct: 557 KGHIISIASSAGLFGVTGLADYCASKFAAVGFDESLRFELEAMGKTGVHTTVVCPYFINT 736

Query: 183 DMTRHLK 189
            M   +K
Sbjct: 737 GMFDGVK 757
>01459
          Length = 536

 Score = 40.8 bits (94), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 27/96 (28%), Positives = 48/96 (50%), Gaps = 3/96 (3%)
 Frame = +3

Query: 143 GQSAYSATKGGLVGFSRSLAKEVARKK--IRVNVVAPGFIRTDMT-RHLKEEHFKKNIPL 199
           G   Y+ATK  +      L  E+  +K  IRV+ V PGF+ T+   RHL +E        
Sbjct: 117 GGHCYTATKFAVTAIREGLRNELRERKSNIRVSQVCPGFVETEFVQRHLDQERANAVYSS 296

Query: 200 GRFGETLEVAHAVVFLLESPYITGHVLIVDGGLQLT 235
            +  +  ++  +++++L++P    HV I D  ++ T
Sbjct: 297 MKCLQAEDIRDSILYILDAP---PHVEINDIHMRPT 395
>18041
          Length = 547

 Score = 40.0 bits (92), Expect = 8e-04,   Method: Compositional matrix adjust.
 Identities = 38/183 (20%), Positives = 77/183 (42%), Gaps = 9/183 (4%)
 Frame = -2

Query: 9   GGSRGIGRAVAQLMAQKGYRLAIVSRNLEVAKVTAGELGGNHLAFRCDVAKEQDVQSTFQ 68
           G + GIG+  A  +A+KG  + ++SRN E     A E+   H      +  +      + 
Sbjct: 546 GSTDGIGKCFALQLAEKGLDIVLISRNPEKLSAVAKEIVDQHKVSVKVITADFKNADIYD 367

Query: 69  EMEKHLG--PVNFLVNAAG-INRGSLLVRTKTEDMISQLHTNLLG-SMLTCKAAMKTMIQ 124
            +++ L    +  LVN  G +NR +     + +D   Q H +++  ++L C      ++ 
Sbjct: 366 NIKRQLTGLDIGILVNNVGMLNRRNPGYFCEADDF-EQFHQDIINVNILACVQMTGIVLP 190

Query: 125 QXXXXXXXXXXXXLKGNVGQ-----SAYSATKGGLVGFSRSLAKEVARKKIRVNVVAPGF 179
           +              G   +     S YS TK  +  F+++L  E + + + + ++ P  
Sbjct: 189 EMLERKRGLIINIASGAAIRPLPFFSVYSGTKAFISHFTQALNMEYSSQGVTIQLLIPNL 10

Query: 180 IRT 182
           + T
Sbjct: 9   VAT 1
>21038
          Length = 377

 Score = 40.0 bits (92), Expect = 9e-04,   Method: Compositional matrix adjust.
 Identities = 28/108 (25%), Positives = 55/108 (50%), Gaps = 4/108 (3%)
 Frame = +3

Query: 22  MAQKGYRLAIVSRN----LEVAKVTAGELGGNHLAFRCDVAKEQDVQSTFQEMEKHLGPV 77
           +A++G ++A+V  N     E  ++ +        A++ DV+  +++Q     +EK LGPV
Sbjct: 15  LARRGCKVAVVDVNSKGCYETVELLSKIPRCTAKAYKNDVSSPRELQLMAVRVEKELGPV 194

Query: 78  NFLVNAAGINRGSLLVRTKTEDMISQLHTNLLGSMLTCKAAMKTMIQQ 125
             LVN A +   +     K++++ + L  NL   ++T K  +  MI +
Sbjct: 195 EILVNNASLMPMTSTPHLKSDEIDTILQLNLGSYIMTTKEFLPKMITR 338
>18534
          Length = 406

 Score = 37.4 bits (85), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 29/125 (23%), Positives = 54/125 (43%), Gaps = 4/125 (3%)
 Frame = -2

Query: 59  KEQDVQSTFQEMEKHLGPVNFLVNAAGINRGSLLVRTKTEDMISQLHTNLLGSMLTCKAA 118
           +EQ  Q   Q ++  +G V+ L+N AGI             + +  + N++    T KA 
Sbjct: 372 REQIYQRAAQVIDD-VGHVDVLINNAGIVCCKPFWELHDRVIQNTYNINIISHYWTVKAF 196

Query: 119 MKTMIQQXXXXXXXXXXXX-LKGNVGQSAYSATKGGLVGFSRSLAKEV---ARKKIRVNV 174
           +  M++              + G  G S Y+ATK   +GF  SL  ++      +I +++
Sbjct: 195 LPHMMRHNRGHIVTVGSVTGMLGTYGCSDYAATKYACIGFHESLLTDLKAHGYDQIHMSL 16

Query: 175 VAPGF 179
           + P +
Sbjct: 15  ICPYY 1
>35662
          Length = 242

 Score = 36.6 bits (83), Expect = 0.009,   Method: Compositional matrix adjust.
 Identities = 21/47 (44%), Positives = 28/47 (59%), Gaps = 3/47 (6%)
 Frame = +2

Query: 191 EHFKKNIPLGRFGETLEVAHAVVFLLESP---YITGHVLIVDGGLQL 234
           E F+  +P  R+G   EV+  V FLL SP   +ITG  + VDGG +L
Sbjct: 26  EVFRDRVPAKRYGTVEEVSATVCFLL-SPAAAFITGETVYVDGGGKL 163
>36857
          Length = 697

 Score = 35.4 bits (80), Expect = 0.019,   Method: Compositional matrix adjust.
 Identities = 18/44 (40%), Positives = 25/44 (56%), Gaps = 2/44 (4%)
 Frame = +3

Query: 147 YSATKGGLVGFSRSLA--KEVARKKIRVNVVAPGFIRTDMTRHL 188
           Y  TK G++ FSRS+A  K+     IRVN + P F+ T +   L
Sbjct: 321 YCGTKAGVMMFSRSVAAHKDYIDNGIRVNTLCPAFVDTPLVAKL 452
>36378
          Length = 552

 Score = 34.3 bits (77), Expect = 0.041,   Method: Compositional matrix adjust.
 Identities = 29/114 (25%), Positives = 49/114 (42%), Gaps = 1/114 (0%)
 Frame = -3

Query: 68  QEMEKHLGPVNFLVNAAGINRGSLLVRTKTEDMISQLHTNLLGSMLTCKAAMKTMIQQXX 127
           Q + +H G ++ LVN AG ++ +  V+T  +     L  N+LG +   KA +  M+Q+  
Sbjct: 391 QTVLQHFGQIDILVNNAGRSQRAEWVKTSLDVDRQMLELNVLGVLSLTKAVLPHMMQRGR 212

Query: 128 XXXXXXXXXXLKGNVGQS-AYSATKGGLVGFSRSLAKEVARKKIRVNVVAPGFI 180
                      K     S +Y+ +K  L G+  SL  E     +R     P  +
Sbjct: 211 GHMVVMSSIAGKCGAPMSGSYTGSKHALHGWFESLRVEGHADTLR*PCCVPACL 50
>27168
          Length = 665

 Score = 31.6 bits (70), Expect = 0.31,   Method: Compositional matrix adjust.
 Identities = 26/104 (25%), Positives = 47/104 (45%), Gaps = 7/104 (6%)
 Frame = +3

Query: 3   KVCAVFGGSRGIGRAVAQLMAQKGYRLAIVSRNLEVAKVTAGELGGNHLAFRC------- 55
           +V  + G + GIG   A+ +A  G  + +  RNL  A+     +     A R        
Sbjct: 189 RVALITGANCGIGFETARSLALHGCEIILACRNLATAQEAIDRIAVERPAARARCRTASL 368

Query: 56  DVAKEQDVQSTFQEMEKHLGPVNFLVNAAGINRGSLLVRTKTED 99
           D+    DV+   +++ + +G +++L+  AG+     L  TKT D
Sbjct: 369 DLGSLSDVKKFVEQIRQSVGHIDYLILNAGV---FALPYTKTVD 491
>23264
          Length = 1871

 Score = 28.9 bits (63), Expect = 1.7,   Method: Compositional matrix adjust.
 Identities = 20/58 (34%), Positives = 34/58 (58%)
 Frame = -1

Query: 67  FQEMEKHLGPVNFLVNAAGINRGSLLVRTKTEDMISQLHTNLLGSMLTCKAAMKTMIQ 124
           F  ++ H   VNF+ +  G  + S  +  KTE+++S LHT + G++L   + M T+IQ
Sbjct: 839 FPYLDIH-KSVNFIQSPFG*CKNSFSI-LKTEEVVSFLHTGVNGAVLRKLSLMYTLIQ 672
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31981233|ref|NP_079933.2| leucine rich repeat
containing 57 [Mus musculus]
         (239 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

34576                                                                  73   1e-13
20480                                                                  54   4e-08
30747                                                                  52   2e-07
09309                                                                  51   4e-07
19531                                                                  47   7e-06
05532                                                                  44   4e-05
20775                                                                  37   0.010
17298                                                                  36   0.013
20131                                                                  28   2.4  
19955                                                                  28   3.1  
37214                                                                  27   5.2  
32218                                                                  27   7.4  
>34576
          Length = 1496

 Score = 72.8 bits (177), Expect = 1e-13,   Method: Compositional matrix adjust.
 Identities = 61/204 (29%), Positives = 92/204 (45%), Gaps = 3/204 (1%)
 Frame = +2

Query: 12  TAQKTGVFQLKDRGLTEFPSELQKLTSNLRTIDLSNNKIDSLPPLIIGKFTXXXXXXXXX 71
           T +K     L      EFP     +TS L  +DLS+NKI  +P   I +           
Sbjct: 317 TLKKLTHLSLGRNAFKEFPRPACSITS-LEILDLSDNKITEIPS-DIAQLLSLRELYMKK 490

Query: 72  XXXTVLPDELCNLKKLETLSLNNNHLRELPSTFGQLSALKTLSLSGNQLGALPPQLCCLR 131
              +V   ELC L+KL+    +NN L +LP     L  L+ L LS NQ    P   C + 
Sbjct: 491 NAVSVFCAELCALQKLQMADFSNNGLLDLPEEVSVLGCLQELDLSNNQFFEFPKTACSIP 670

Query: 132 HLDVVDLSKNQ---IRSIPDTVGELQAIELNLNQNQISQLSVKISCCPRLKVLRLEENCL 188
           HL  +  S+ +   + S+PD +      EL L+ N +  L   IS    L VL+ + N  
Sbjct: 671 HLHKLVFSQQEGLKVPSLPDEIEFSSVAELVLSHNTLRTLPRTISAMKNLVVLKADHN-- 844

Query: 189 ELSMLPQSILSDSQICLLAVEGNL 212
           E+ +LP ++   + + +L +  NL
Sbjct: 845 EICVLPDALCDMTALQVLHLNDNL 916

 Score = 60.8 bits (146), Expect = 4e-10,   Method: Compositional matrix adjust.
 Identities = 43/152 (28%), Positives = 70/152 (46%), Gaps = 1/152 (0%)
 Frame = +2

Query: 38  SNLRTIDLSNNKIDSLPPLIIGKFTXXXXXXXXXXXXTVLPDELCNLKKLETLSLNNNHL 97
           SNL  + L  N ++ LP +                  T +P  + +L +LE L L+ N L
Sbjct: 116 SNLEILSLHKNHLERLP-VEFANLRKITRLILSDNNFTSVPVAIGSLTELEALLLDGNSL 292

Query: 98  RELPSTFGQLSALKTLSLSGNQLGALPPQLCCLRHLDVVDLSKNQIRSIPDTVGELQAI- 156
            E+P   G L  L  LSL  N     P   C +  L+++DLS N+I  IP  + +L ++ 
Sbjct: 293 HEIPQELGTLKKLTHLSLGRNAFKEFPRPACSITSLEILDLSDNKITEIPSDIAQLLSLR 472

Query: 157 ELNLNQNQISQLSVKISCCPRLKVLRLEENCL 188
           EL + +N +S    ++    +L++     N L
Sbjct: 473 ELYMKKNAVSVFCAELCALQKLQMADFSNNGL 568

 Score = 58.9 bits (141), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 53/195 (27%), Positives = 85/195 (43%), Gaps = 4/195 (2%)
 Frame = +2

Query: 7   RAHVETA--QKTGVFQLKDRGLTEFPSELQKLTSNLRTIDLSNNKIDSLPPLIIGKFTXX 64
           R  VE A  +K     L D   T  P  +  LT  L  + L  N +  +P   +G     
Sbjct: 158 RLPVEFANLRKITRLILSDNNFTSVPVAIGSLTE-LEALLLDGNSLHEIPQ-ELGTLKKL 331

Query: 65  XXXXXXXXXXTVLPDELCNLKKLETLSLNNNHLRELPSTFGQLSALKTLSLSGNQLGALP 124
                        P   C++  LE L L++N + E+PS   QL +L+ L +  N +    
Sbjct: 332 THLSLGRNAFKEFPRPACSITSLEILDLSDNKITEIPSDIAQLLSLRELYMKKNAVSVFC 511

Query: 125 PQLCCLRHLDVVDLSKNQIRSIPDTVGELQAI-ELNLNQNQISQLSVKISCCPRL-KVLR 182
            +LC L+ L + D S N +  +P+ V  L  + EL+L+ NQ  +        P L K++ 
Sbjct: 512 AELCALQKLQMADFSNNGLLDLPEEVSVLGCLQELDLSNNQFFEFPKTACSIPHLHKLVF 691

Query: 183 LEENCLELSMLPQSI 197
            ++  L++  LP  I
Sbjct: 692 SQQEGLKVPSLPDEI 736

 Score = 57.0 bits (136), Expect = 6e-09,   Method: Compositional matrix adjust.
 Identities = 37/124 (29%), Positives = 62/124 (50%), Gaps = 1/124 (0%)
 Frame = +2

Query: 75  TVLPDELCNLKKLETLSLNNNHLRELPSTFGQLSALKTLSLSGNQLGALPPQLCCLRHLD 134
           T++P+ +C    LE LSL+ NHL  LP  F  L  +  L LS N   ++P  +  L  L+
Sbjct: 86  TLIPESICWCSNLEILSLHKNHLERLPVEFANLRKITRLILSDNNFTSVPVAIGSLTELE 265

Query: 135 VVDLSKNQIRSIPDTVGELQAI-ELNLNQNQISQLSVKISCCPRLKVLRLEENCLELSML 193
            + L  N +  IP  +G L+ +  L+L +N   +          L++L L +N  +++ +
Sbjct: 266 ALLLDGNSLHEIPQELGTLKKLTHLSLGRNAFKEFPRPACSITSLEILDLSDN--KITEI 439

Query: 194 PQSI 197
           P  I
Sbjct: 440 PSDI 451

 Score = 48.5 bits (114), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 35/116 (30%), Positives = 59/116 (50%), Gaps = 1/116 (0%)
 Frame = +2

Query: 75  TVLPDELCNLKKLETLSLNNNHLRELPSTFGQLSALKTLSLSGNQLGALPPQLCCLRHLD 134
           TVLP+++  L +L+ +   +N L  +P +    S L+ LSL  N L  LP +   LR + 
Sbjct: 17  TVLPEDIAELFELKEVYCGSNQLTLIPESICWCSNLEILSLHKNHLERLPVEFANLRKIT 196

Query: 135 VVDLSKNQIRSIPDTVGELQAIE-LNLNQNQISQLSVKISCCPRLKVLRLEENCLE 189
            + LS N   S+P  +G L  +E L L+ N + ++  ++    +L  L L  N  +
Sbjct: 197 RLILSDNNFTSVPVAIGSLTELEALLLDGNSLHEIPQELGTLKKLTHLSLGRNAFK 364

 Score = 46.2 bits (108), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 47/172 (27%), Positives = 76/172 (44%), Gaps = 2/172 (1%)
 Frame = +2

Query: 30  PSELQKLTSNLRTIDLSNNKIDSLPPLIIGKFTXXXXXXXXXXXXTVLPDELCNLKKLET 89
           P E++   S++  + LS+N + +LP   I                 VLPD LC++  L+ 
Sbjct: 725 PDEIE--FSSVAELVLSHNTLRTLP-RTISAMKNLVVLKADHNEICVLPDALCDMTALQV 895

Query: 90  LSLNNNHLRELPSTFGQLSALKTLSLSGNQLGALPPQLCCLRHLDVVDLSKNQIRSIPDT 149
           L LN+N L  LP  F QL  L+ L L  N L + P  +C    L  +     +     D 
Sbjct: 896 LHLNDNLLPTLPLEFDQLKGLQDLCLHNNPLRSPPMDVCVSGVLQPIGRFIRRAVEREDM 1075

Query: 150 V--GELQAIELNLNQNQISQLSVKISCCPRLKVLRLEENCLELSMLPQSILS 199
           +     +A++  LN+N++  L  K    P  K++ LE+       LP  + +
Sbjct: 1076LLARMFEAMKFALNKNELRYLMKKFR-FPDDKMVELEQTYHGKEQLPNRVYA 1228

 Score = 29.3 bits (64), Expect = 1.7,   Method: Compositional matrix adjust.
 Identities = 29/103 (28%), Positives = 54/103 (52%), Gaps = 2/103 (1%)
 Frame = +2

Query: 117 GNQLGALPPQLCCLRHLDVVDLSKNQIRSIPDTVGELQAIE-LNLNQNQISQLSVKISCC 175
            N L  LP  +  L  L  V    NQ+  IP+++     +E L+L++N + +L V+ +  
Sbjct: 5   NNCLTVLPEDIAELFELKEVYCGSNQLTLIPESICWCSNLEILSLHKNHLERLPVEFANL 184

Query: 176 PRLKVLRLEENCLELSMLPQSILSDSQICLLAVEGN-LFEIKK 217
            ++  L L +N    + +P +I S +++  L ++GN L EI +
Sbjct: 185 RKITRLILSDN--NFTSVPVAIGSLTELEALLLDGNSLHEIPQ 307
>20480
          Length = 638

 Score = 54.3 bits (129), Expect = 4e-08,   Method: Compositional matrix adjust.
 Identities = 32/107 (29%), Positives = 56/107 (52%)
 Frame = -1

Query: 84  LKKLETLSLNNNHLRELPSTFGQLSALKTLSLSGNQLGALPPQLCCLRHLDVVDLSKNQI 143
           L KL+ L L+NN +  + S    L  L+ L L+GN++ A+P  +  ++ L V+ +++N++
Sbjct: 437 LPKLQILDLSNNDIEAVSSELSGLQTLRQLILNGNKMEAIPGSIGFMKELRVLGVNENRL 258

Query: 144 RSIPDTVGELQAIELNLNQNQISQLSVKISCCPRLKVLRLEENCLEL 190
           R +PD++G L+ +E                      +L LE NCLE 
Sbjct: 257 REVPDSIGNLENLE----------------------ILGLERNCLEF 183

 Score = 39.3 bits (90), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 36/123 (29%), Positives = 54/123 (43%)
 Frame = -1

Query: 5   ALRAHVETAQKTGVFQLKDRGLTEFPSELQKLTSNLRTIDLSNNKIDSLPPLIIGKFTXX 64
           A+   V    K  +  L +  +    SEL  L + LR + L+ NK++++P   IG     
Sbjct: 461 AVNRSVFRLPKLQILDLSNNDIEAVSSELSGLQT-LRQLILNGNKMEAIPG-SIGFMKEL 288

Query: 65  XXXXXXXXXXTVLPDELCNLKKLETLSLNNNHLRELPSTFGQLSALKTLSLSGNQLGALP 124
                       +PD + NL+ LE L L  N L  L     +L  L  L LSGN +  LP
Sbjct: 287 RVLGVNENRLREVPDSIGNLENLEILGLERNCLEFLNPVVCKLEGLLRLGLSGNHMTNLP 108

Query: 125 PQL 127
            ++
Sbjct: 107 REV 99

 Score = 38.1 bits (87), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 19/44 (43%), Positives = 28/44 (63%)
 Frame = -2

Query: 75  TVLPDELCNLKKLETLSLNNNHLRELPSTFGQLSALKTLSLSGN 118
           T +PD + +L++L  LSL+NN + E+P     L  L+ L LSGN
Sbjct: 601 TQMPDPVFDLEQLVCLSLSNNKITEIPDAISHLDNLEVLVLSGN 470
>30747
          Length = 1168

 Score = 52.4 bits (124), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 49/159 (30%), Positives = 80/159 (50%), Gaps = 22/159 (13%)
 Frame = +3

Query: 79  DELCNLKKLETLSLNNNHLRELPSTFGQLSALKTLSLSGNQLGALPPQLCC--------- 129
           +EL +   + TL L+NNH+  L S    L  L+ L +SGN +  L     C         
Sbjct: 516 NELLSCVNISTLDLSNNHITNL-SALSYLPNLEELFVSGNSIQKLTDLHRCKKLSELDLS 692

Query: 130 ------------LRHLDVVDLSKNQIRSIPDTVGELQAIE-LNLNQNQISQLSVKISCCP 176
                       L  L  +D+S N+++S+  ++G+L+++E LNLN NQIS+L    SC P
Sbjct: 693 RNRLVDISGISGLPALQTLDMSDNRLKSVT-SLGKLKSLETLNLNGNQISELLGWGSCFP 869

Query: 177 RLKVLRLEENCLELSMLPQSILSDSQICLLAVEGNLFEI 215
           +L++L+L +N          + +  Q+C L   G+L E+
Sbjct: 870 KLQILKLCDNM---------VTAWKQVCCLKELGDLNEV 959
>09309
          Length = 1508

 Score = 50.8 bits (120), Expect = 4e-07,   Method: Compositional matrix adjust.
 Identities = 43/144 (29%), Positives = 67/144 (46%), Gaps = 3/144 (2%)
 Frame = +3

Query: 11  ETAQKTGV--FQLKDRGLTEFPSELQKLTSNLRTIDLSNNKIDSLPPLIIGKFTXXXXXX 68
           E AQ+  V    +     T+ PS L  L ++L  +++  NK+  L P  IG F       
Sbjct: 417 EKAQEAAVTSVNISKNQFTQLPSNLFLLVNSLTELNMGFNKLTGLSP-DIGLFLKLTCLD 593

Query: 69  XXXXXXTVLPDELCNLKKLETLSLNNNHLRELPSTFGQLSALKTLSLSGNQLGALPPQ-L 127
                 + LP ELC+++ L  + L+ N   E+P    +L  L+ L L+ NQ+  + P  L
Sbjct: 594 LRNNGLSSLPAELCSMQALREVILSCNRFTEIPQALYELKKLEILFLNDNQVSTIEPSGL 773

Query: 128 CCLRHLDVVDLSKNQIRSIPDTVG 151
             L  L  +DL  N I  +P  +G
Sbjct: 774 QRLGVLATLDLQNNNISQVPPELG 845

 Score = 39.3 bits (90), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 19/47 (40%), Positives = 32/47 (68%)
 Frame = +3

Query: 77  LPDELCNLKKLETLSLNNNHLRELPSTFGQLSALKTLSLSGNQLGAL 123
           LPDE+  L+ LE L L+NN +  LP + G +++LK++ L GN + ++
Sbjct: 63  LPDEITLLENLERLDLSNNDISMLPYSLGTINSLKSVILDGNPMKSI 203
>19531
          Length = 415

 Score = 47.0 bits (110), Expect = 7e-06,   Method: Compositional matrix adjust.
 Identities = 35/105 (33%), Positives = 57/105 (54%), Gaps = 1/105 (0%)
 Frame = -2

Query: 75  TVLPDELCNLKKLETLSLNNNHLRELPSTFGQLSALKTLSLSGNQLGALPPQLCCLRHLD 134
           T L + L  L  L  L +++NHL+ LP+  G+L  L+ L++S NQL  LP  +  L +L 
Sbjct: 333 TSLGEGLAQLPALTVLDVHDNHLQSLPNALGELENLQKLNISHNQLVELPSCIGRLSNLV 154

Query: 135 VVDLSKNQIRSI-PDTVGELQAIELNLNQNQISQLSVKISCCPRL 178
            V    N++  I PD V   +  EL+++ N +++L   I    R+
Sbjct: 153 SVHAEHNKLTLICPDLVDCRKLEELDVSNNDLAELPKYIGLLSRM 19

 Score = 43.1 bits (100), Expect = 9e-05,   Method: Compositional matrix adjust.
 Identities = 30/99 (30%), Positives = 53/99 (53%)
 Frame = -2

Query: 18  VFQLKDRGLTEFPSELQKLTSNLRTIDLSNNKIDSLPPLIIGKFTXXXXXXXXXXXXTVL 77
           V  + D  L   P+ L +L  NL+ +++S+N++  LP   IG+ +            T++
Sbjct: 291 VLDVHDNHLQSLPNALGEL-ENLQKLNISHNQLVELPS-CIGRLSNLVSVHAEHNKLTLI 118

Query: 78  PDELCNLKKLETLSLNNNHLRELPSTFGQLSALKTLSLS 116
             +L + +KLE L ++NN L ELP   G LS +  L+++
Sbjct: 117 CPDLVDCRKLEELDVSNNDLAELPKYIGLLSRMFRLNVA 1

 Score = 40.8 bits (94), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 31/91 (34%), Positives = 52/91 (57%), Gaps = 1/91 (1%)
 Frame = -2

Query: 89  TLSLNNNHLRELPSTFGQLSALKTLSLSGNQLGALPPQLCCLRHLDVVDLSKNQIRSIPD 148
           T+SL+N   R     + + + L  L L+ N L +L   L  L  L V+D+  N ++S+P+
Sbjct: 414 TVSLDNTEDR-----WWEQTDLTKLILASNALTSLGEGLAQLPALTVLDVHDNHLQSLPN 250

Query: 149 TVGELQAIE-LNLNQNQISQLSVKISCCPRL 178
            +GEL+ ++ LN++ NQ+ +L    SC  RL
Sbjct: 249 ALGELENLQKLNISHNQLVELP---SCIGRL 166
>05532
          Length = 1607

 Score = 44.3 bits (103), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 33/89 (37%), Positives = 46/89 (51%), Gaps = 1/89 (1%)
 Frame = +3

Query: 80  ELCNLKKLETLSLNNNHLRELPSTFGQLSALKTLSLSGNQLGALPPQLCCLRHLDVVDLS 139
           EL   + L  L LN+N L  +     QL  L  L LS NQL +LP ++  L  L  + L 
Sbjct: 162 ELFRFQHLTCLYLNDNRLDHISPHVSQLHHLVCLDLSSNQLSSLPSEIGDLTELRELLLY 341

Query: 140 KNQIRSIPDTVGEL-QAIELNLNQNQISQ 167
            NQ+ S+P  +G L Q   L++  N +SQ
Sbjct: 342 NNQLTSLPFELGRLFQLQNLDIKGNPLSQ 428

 Score = 43.5 bits (101), Expect = 8e-05,   Method: Compositional matrix adjust.
 Identities = 29/93 (31%), Positives = 50/93 (53%), Gaps = 1/93 (1%)
 Frame = +3

Query: 97  LRELPSTFGQLSALKTLSLSGNQLGALPPQLCCLRHLDVVDLSKNQIRSIPDTVGELQAI 156
           +R +     +   L  L L+ N+L  + P +  L HL  +DLS NQ+ S+P  +G+L  +
Sbjct: 144 VRNISPELFRFQHLTCLYLNDNRLDHISPHVSQLHHLVCLDLSSNQLSSLPSEIGDLTEL 323

Query: 157 -ELNLNQNQISQLSVKISCCPRLKVLRLEENCL 188
            EL L  NQ++ L  ++    +L+ L ++ N L
Sbjct: 324 RELLLYNNQLTSLPFELGRLFQLQNLDIKGNPL 422

 Score = 31.2 bits (69), Expect = 0.39,   Method: Compositional matrix adjust.
 Identities = 29/100 (29%), Positives = 42/100 (42%)
 Frame = +3

Query: 21  LKDRGLTEFPSELQKLTSNLRTIDLSNNKIDSLPPLIIGKFTXXXXXXXXXXXXTVLPDE 80
           L D  L      + +L  +L  +DLS+N++ S                        LP E
Sbjct: 198 LNDNRLDHISPHVSQL-HHLVCLDLSSNQLSS------------------------LPSE 302

Query: 81  LCNLKKLETLSLNNNHLRELPSTFGQLSALKTLSLSGNQL 120
           + +L +L  L L NN L  LP   G+L  L+ L + GN L
Sbjct: 303 IGDLTELRELLLYNNQLTSLPFELGRLFQLQNLDIKGNPL 422
>20775
          Length = 1020

 Score = 36.6 bits (83), Expect = 0.010,   Method: Compositional matrix adjust.
 Identities = 38/133 (28%), Positives = 63/133 (47%), Gaps = 8/133 (6%)
 Frame = -3

Query: 75  TVLPDELCNLKKLETLSLNNNHLRELPSTFGQLSALKTLSLSGNQLGALPPQLC-CLRHL 133
           + LPD   N + +++L L NN+   LP    ++   + L +S + L +    +   +  L
Sbjct: 550 STLPDNFLNGEIIDSLILKNNNFTALPVALTKVEHXRRLDVSFSALVSFSFDILENVSGL 371

Query: 134 DVVDLSKNQIRSIPDTVGE------LQAIELNLNQNQISQLSVK-ISCCPRLKVLRLEEN 186
           ++VD+S N++     TVGE      L   ELNL  N I ++     S   +L  L L +N
Sbjct: 370 EMVDMSSNKLL-YASTVGESSAGVMLGXKELNLASNAIDRIEDGFFSRMDKLTTLNLSDN 194

Query: 187 CLELSMLPQSILS 199
              LS + Q+  S
Sbjct: 193 --HLSQVTQTTFS 161
>17298
          Length = 476

 Score = 36.2 bits (82), Expect = 0.013,   Method: Compositional matrix adjust.
 Identities = 19/53 (35%), Positives = 30/53 (56%)
 Frame = +3

Query: 93  NNNHLRELPSTFGQLSALKTLSLSGNQLGALPPQLCCLRHLDVVDLSKNQIRS 145
           NNN + ++P+    L  L  L+L+ NQ+  LP +LC    L  + LS N+I+ 
Sbjct: 261 NNNAITDVPADLSSLPHLNCLNLADNQIEELPNELCECTRLKELKLSGNKIKD 419

 Score = 33.5 bits (75), Expect = 0.069,   Method: Compositional matrix adjust.
 Identities = 18/46 (39%), Positives = 29/46 (63%)
 Frame = +3

Query: 75  TVLPDELCNLKKLETLSLNNNHLRELPSTFGQLSALKTLSLSGNQL 120
           T +P +L +L  L  L+L +N + ELP+   + + LK L LSGN++
Sbjct: 276 TDVPADLSSLPHLNCLNLADNQIEELPNELCECTRLKELKLSGNKI 413

 Score = 29.3 bits (64), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 17/51 (33%), Positives = 30/51 (58%), Gaps = 1/51 (1%)
 Frame = +3

Query: 116 SGNQLGALPPQLCCLRHLDVVDLSKNQIRSIPDTVGELQAI-ELNLNQNQI 165
           + N +  +P  L  L HL+ ++L+ NQI  +P+ + E   + EL L+ N+I
Sbjct: 261 NNNAITDVPADLSSLPHLNCLNLADNQIEELPNELCECTRLKELKLSGNKI 413

 Score = 28.9 bits (63), Expect = 2.0,   Method: Compositional matrix adjust.
 Identities = 21/59 (35%), Positives = 31/59 (52%), Gaps = 1/59 (1%)
 Frame = +3

Query: 129 CLRHLDVVDLSKNQIRSIPDTVGELQAIE-LNLNQNQISQLSVKISCCPRLKVLRLEEN 186
           CL   D++  + N I  +P  +  L  +  LNL  NQI +L  ++  C RLK L+L  N
Sbjct: 234 CLTGSDII-ANNNAITDVPADLSSLPHLNCLNLADNQIEELPNELCECTRLKELKLSGN 407
>20131
          Length = 574

 Score = 28.5 bits (62), Expect = 2.4,   Method: Compositional matrix adjust.
 Identities = 14/31 (45%), Positives = 18/31 (58%)
 Frame = +1

Query: 121 GALPPQLCCLRHLDVVDLSKNQIRSIPDTVG 151
           G+ PP    LRH D V L ++QI S+P  V 
Sbjct: 367 GSCPPVFILLRHQDHVTLVESQICSLPRYVA 459
>19955
          Length = 634

 Score = 28.1 bits (61), Expect = 3.1,   Method: Compositional matrix adjust.
 Identities = 27/85 (31%), Positives = 45/85 (52%), Gaps = 2/85 (2%)
 Frame = -2

Query: 79  DELCNLKKLETLSLNNNHLRELPSTFGQLSALKTLSLSGNQLGALPPQLCCLRHLDVVDL 138
           + L +L++L  L L +N + ++ +    L +L+ L L  N++  +   L  L  LDV+DL
Sbjct: 249 NHLNSLRRLIFLDLYDNQIEQI-AGLSSLKSLRVLMLGKNRIKRIE-NLDTLIKLDVLDL 76

Query: 139 SKNQIRSIP--DTVGELQAIELNLN 161
             NQI  I   + +GEL  + L  N
Sbjct: 75  HGNQITRIENLNHLGELLVLNLAGN 1
>37214
          Length = 316

 Score = 27.3 bits (59), Expect = 5.2,   Method: Compositional matrix adjust.
 Identities = 14/26 (53%), Positives = 17/26 (65%)
 Frame = -2

Query: 29  FPSELQKLTSNLRTIDLSNNKIDSLP 54
           FP  L    SNL T+ LS+NKI S+P
Sbjct: 135 FPGMLHAF-SNLSTLQLSDNKISSIP 61
>32218
          Length = 418

 Score = 26.9 bits (58), Expect = 7.4,   Method: Compositional matrix adjust.
 Identities = 17/64 (26%), Positives = 30/64 (46%)
 Frame = -2

Query: 131 RHLDVVDLSKNQIRSIPDTVGELQAIELNLNQNQISQLSVKISCCPRLKVLRLEENCLEL 190
           RH       K+  +S P   GE + + L+  QNQ + L+ K +   +    +  +NC +L
Sbjct: 345 RHKSSG*TEKHADKSRPAGKGENRTLVLHQRQNQRNPLAAKRTQLHQKPASQTAKNCTQL 166

Query: 191 SMLP 194
             +P
Sbjct: 165 QRIP 154
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|63562032|ref|XP_133706.4| PREDICTED: similar to
Protein FAM57B isoform 1 [Mus musculus]
         (271 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

26227                                                                  73   1e-13
18481                                                                  30   1.0  
31059                                                                  30   1.2  
02447                                                                  28   4.3  
07914                                                                  27   8.4  
>26227
          Length = 413

 Score = 72.8 bits (177), Expect = 1e-13,   Method: Compositional matrix adjust.
 Identities = 45/142 (31%), Positives = 71/142 (50%), Gaps = 1/142 (0%)
 Frame = +1

Query: 1   MVAGGVVFPGLFLLSKNTLQRLPQLRWEEADAVIVSARLVSSVQAIMASTAGYIVSTSCK 60
           ++AG + FP ++   K  L      R    D  ++S R   S+QAIM+  AG I+ +S  
Sbjct: 16  LLAGSLYFPLVYSGIKTLLTNRFGRRLSTGDICLISERCTCSIQAIMSVVAGAIIVSSVD 195

Query: 61  HIIDDQHWLSSAYTQFAVPYFIYDIYAMFLCH-WHKHQVKGHGGEDGTPRALGSTWAVVR 119
            I+ D HWLS+ Y  F++ YFI+D+ AM+L   W+          D   R+L      +R
Sbjct: 196 DIMTDTHWLSNTYACFSLSYFIHDLRAMYLTFVWNA---------DEKIRSLPLAEK-LR 345

Query: 120 GYLHKEFLMVLHHAAMVLVCFP 141
            ++    ++V HH  M  + FP
Sbjct: 346 LFIRSSSMLVFHHTVMPAIIFP 411
>18481
          Length = 437

 Score = 30.0 bits (66), Expect = 1.0,   Method: Compositional matrix adjust.
 Identities = 16/44 (36%), Positives = 20/44 (45%)
 Frame = -1

Query: 207 LYWAYGRHAGLPLLSVPMAIPAHVNLGAALLLAPQLYWFFLICR 250
           +Y   GRH GLP +        H N     LL P L   F+IC+
Sbjct: 341 VYEQIGRHPGLPTM-YHYGTEKHFNALVMELLGPSLEELFVICK 213
>31059
          Length = 515

 Score = 30.0 bits (66), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 12/23 (52%), Positives = 14/23 (60%)
 Frame = +3

Query: 242 LYWFFLICRGACRLFRPRGSPPP 264
           LY   LICR   +  R RG+PPP
Sbjct: 447 LYTVVLICRNNNKAKRERGNPPP 515
>02447
          Length = 403

 Score = 28.1 bits (61), Expect = 4.3,   Method: Compositional matrix adjust.
 Identities = 20/63 (31%), Positives = 27/63 (42%), Gaps = 3/63 (4%)
 Frame = +3

Query: 172 KILIQYKQQHTLLHKVNGALMLLSFLCCRVLLFPYLYWA--YGRHAGLPLLS-VPMAIPA 228
           K+ I+   +    H  N   MLL F C   LLF  L+W   +   +   LLS V     +
Sbjct: 75  KVTIKPTSKRNRTHYSNFTYMLLGFDCKGTLLFLELFWVLLFSSQSNTGLLSPVSFGRQS 254

Query: 229 HVN 231
           H N
Sbjct: 255 HYN 263
>07914
          Length = 1120

 Score = 26.9 bits (58), Expect = 8.4,   Method: Compositional matrix adjust.
 Identities = 11/23 (47%), Positives = 17/23 (73%)
 Frame = +2

Query: 176 QYKQQHTLLHKVNGALMLLSFLC 198
           +YKQQH  +H++  A+ L +FLC
Sbjct: 962 EYKQQHISVHRIRSAI-LTAFLC 1027
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|85861231|ref|NP_001034290.1| haloacid
dehalogenase-like hydrolase domain containing 2 isoform 1 [Mus
musculus]
         (259 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

05932                                                                  73   1e-13
>05932
          Length = 522

 Score = 73.2 bits (178), Expect = 1e-13,   Method: Compositional matrix adjust.
 Identities = 34/79 (43%), Positives = 45/79 (56%)
 Frame = -1

Query: 178 GKPEKTFFLEALRDADCAPEEAVMIGDDCRDDVDGAQNIGMLGILVKTGKYKAADEEKIN 237
           GKP + FF   L      P+  VM+GDD  +DV GAQ   M G+LV+TGKY+ +DE    
Sbjct: 522 GKPSQAFFTSVLDSMGATPQHTVMVGDDIENDVXGAQRCAMTGVLVRTGKYRXSDENHKT 343

Query: 238 PPPYLTCESFPHAVDHILQ 256
             P L  ++   AVD IL+
Sbjct: 342 VKPDLIADNLSAAVDEILK 286
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|118150670|ref|NP_032228.2| solute carrier family 39,
member 7 [Mus musculus]
         (476 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

17405                                                                  73   2e-13
11352                                                                  49   9e-09
17175                                                                  33   0.37 
>17405
          Length = 480

 Score = 73.2 bits (178), Expect = 2e-13,   Method: Compositional matrix adjust.
 Identities = 40/114 (35%), Positives = 58/114 (50%)
 Frame = -3

Query: 333 DLAHNFTDGLAIGASFRGGRGLGILTTMTVLLHEVPHEVGDFAILVQSGCSKKQAMRLQL 392
           D  HNF+DGLAIGA+F      GI T++ +  HE+PHE+GDFA+L+++G S KQA+    
Sbjct: 475 DGIHNFSDGLAIGAAFASSVTGGISTSIAIFCHELPHEIGDFAVLLRAGMSVKQAIVYNC 296

Query: 393 VXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXWVLPFTAGGFIYVATVSVLPEL 446
           V                               W+    AG F+Y++ V +LPE+
Sbjct: 295 V--------SSVLAFIGMLIGVAIGNIHNASIWIFAGVAGMFLYISMVDMLPEM 158
>11352
          Length = 863

 Score = 48.5 bits (114), Expect(2) = 9e-09,   Method: Compositional matrix adjust.
 Identities = 34/118 (28%), Positives = 52/118 (44%), Gaps = 7/118 (5%)
 Frame = +1

Query: 345 GASFRGGRGLGILTTMTVLLHEVPHEVGDFAILVQSGCSKKQAMRLQLVXXXXXXXXXXX 404
           GA+F     LG+   + VL  E+PHE+GD AIL+ SG + K+A+ L  +           
Sbjct: 331 GAAFTENVYLGVSIGIAVLCEELPHELGDVAILLHSGMTMKRALCLNFL--------SAC 486

Query: 405 XXXXXXXXXXXXXXXXXXXXWVLPFTAGGFIYVATVSVLPEL-------LREASPLQS 455
                               W+L    G F+YV  V +LPE+       +RE + L++
Sbjct: 487 VCYVGLVIGIVLGENTDANRWILAVAGGLFLYVPLVDMLPEMSQHLDLTMREGNLLEN 660

 Score = 29.3 bits (64), Expect(2) = 9e-09,   Method: Compositional matrix adjust.
 Identities = 12/26 (46%), Positives = 16/26 (61%)
 Frame = +3

Query: 327 YLNLAADLAHNFTDGLAIGASFRGGR 352
           ++ L  D+ HNF DG+AIG    G R
Sbjct: 276 WMVLIGDVMHNFVDGMAIGGRLHGER 353
>17175
          Length = 512

 Score = 32.7 bits (73), Expect = 0.37,   Method: Compositional matrix adjust.
 Identities = 17/51 (33%), Positives = 28/51 (54%)
 Frame = +1

Query: 327 YLNLAADLAHNFTDGLAIGASFRGGRGLGILTTMTVLLHEVPHEVGDFAIL 377
           +++++ DL+H   DG++IG S RG    GI     V LH V    G  +++
Sbjct: 49  FVHVSGDLSHKHFDGISIGFSLRGDLS*GIHVACVVKLHHVNSTGGRCSVV 201
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|14030773|ref|NP_114387.1| testis specific gene A14
[Mus musculus]
         (373 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

37560                                                                  73   2e-13
>37560
          Length = 469

 Score = 72.8 bits (177), Expect = 2e-13,   Method: Compositional matrix adjust.
 Identities = 54/146 (36%), Positives = 81/146 (55%), Gaps = 1/146 (0%)
 Frame = -2

Query: 215 KNAHGKIIILYDEDERLASQAATTMCERGFENLFMLSGGLKVLAQKFPEGLV-TGSLPAS 273
           K   GKIIILYD DE LA +AATT+ +RG++NLF+LSGGLKV ++ F + +   G+LPAS
Sbjct: 441 KTKEGKIIILYDNDEILAHKAATTLVQRGYDNLFILSGGLKVASRIFAKRVW*RGTLPAS 262

Query: 274 CQQALPFGSVRKRRGPKMPALPAENKWRFTPEDLKKIECYLEEDQGPADNPSRLNQNNSA 333
             +    G   K   P      A +K  FT  D+  +  Y+++  G + + SRL+ ++  
Sbjct: 261 FTEGGGGGGKGKGSAPPPAPKEAADKKDFTLADMGYLIDYMDDALGDSSSSSRLSHHSKG 82

Query: 334 GKDSKVAACRGGQNLPTSCPASHSSP 359
           G  S+++         +S  A H  P
Sbjct: 81  GTSSRMST-------ASSTAARHGRP 25
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|160707976|ref|NP_036125.4| piccolo isoform 1 [Mus
musculus]
         (5068 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

29179                                                                  77   2e-13
16549                                                                  65   8e-10
31935                                                                  50   2e-05
26525                                                                  42   3e-05
30040                                                                  49   4e-05
20073                                                                  46   3e-04
01494                                                                  42   0.008
14539                                                                  36   0.35 
25445                                                                  28   2.2  
30297                                                                  32   6.4  
26047                                                                  32   8.3  
>29179
          Length = 1113

 Score = 77.0 bits (188), Expect = 2e-13,   Method: Composition-based stats.
 Identities = 50/153 (32%), Positives = 80/153 (52%), Gaps = 9/153 (5%)
 Frame = -3

Query: 4611 PTDVSKTASHPIT-------GEIQLQINYDLGNLII--HILQARNLVPRDNNGYSDPFVK 4661
            P  V + A+ PI        G IQ  + YD  NL +   I++A +L  +D  G SDP+VK
Sbjct: 598  PEVVEEHATGPIVEGVDYKLGRIQFGLMYDFQNLTLTLRIIRAVDLPAKDVTGTSDPYVK 419

Query: 4662 VYLLPGRGQVMVVQNASVEYKRRTKYVQKSLNPEWNQTVIYKSISMEQLMKKTLEVTVWD 4721
            + LLP +           ++K  TK  +++LNP WN+  +++     +L++KTL + V D
Sbjct: 418  ILLLPDK-----------KHKLLTKVKKRNLNPHWNECFLFEGWPHNKLLEKTLYLQVID 272

Query: 4722 YDRFSSNDFLGEVLIDLSSTSHLDNTPRWYPLK 4754
            YDRFS +D +GE  + L+      +   W  L+
Sbjct: 271  YDRFSRDDPIGETYLPLNEIDLSQSPVSWKYLQ 173

 Score = 33.5 bits (75), Expect = 2.3,   Method: Composition-based stats.
 Identities = 31/116 (26%), Positives = 51/116 (43%), Gaps = 3/116 (2%)
 Frame = -3

Query: 4948 DGEQLIVEILQCRNITYKFKSPDHLPDLYVKIYVINIATQKKVIKKKTRVCRHDREPSFN 5007
            D + L + +   R +    K      D YVKI ++     K + K K R    +  P +N
Sbjct: 511  DFQNLTLTLRIIRAVDLPAKDVTGTSDPYVKILLLPDKKHKLLTKVKKR----NLNPHWN 344

Query: 5008 ETFRFSLSPAGHSLQILLF---SNGGKFMKKTLIGEACIWLDKVDLRKRIVNWHKL 5060
            E F F   P    L+  L+    +  +F +   IGE  + L+++DL +  V+W  L
Sbjct: 343  ECFLFEGWPHNKLLEKTLYLQVIDYDRFSRDDPIGETYLPLNEIDLSQSPVSWKYL 176
>16549
          Length = 607

 Score = 64.7 bits (156), Expect = 8e-10,   Method: Compositional matrix adjust.
 Identities = 36/98 (36%), Positives = 56/98 (57%)
 Frame = +2

Query: 4658 PFVKVYLLPGRGQVMVVQNASVEYKRRTKYVQKSLNPEWNQTVIYKSISMEQLMKKTLEV 4717
            P+VK YLLP         +   + KR+TK V+ S++P +N+ + Y+    E    +TL+V
Sbjct: 65   PYVKTYLLP---------DPEKQTKRKTKIVKHSVHPTFNEVLQYRMKETET-RHRTLQV 214

Query: 4718 TVWDYDRFSSNDFLGEVLIDLSSTSHLDNTPRWYPLKE 4755
            TVWD+D    N+FLG V + L      D+T +WY L++
Sbjct: 215  TVWDHDMLKENNFLGAVYLRLRDLELSDDTAKWYTLQK 328
>31935
          Length = 554

 Score = 50.4 bits (119), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 37/107 (34%), Positives = 55/107 (51%), Gaps = 2/107 (1%)
 Frame = -3

Query: 4624 GEIQLQINYDLGN--LIIHILQARNLVPRDNNGYSDPFVKVYLLPGRGQVMVVQNASVEY 4681
            G IQL I Y      L + I +  N+  RD +   DP+VK++LLPGR +         E 
Sbjct: 537  GRIQLTITYSAQRQKLDVTIHKIMNIPLRDPSSIPDPYVKLHLLPGRSK---------ES 385

Query: 4682 KRRTKYVQKSLNPEWNQTVIYKSISMEQLMKKTLEVTVWDYDRFSSN 4728
            KR+T  ++ + NP ++ +  Y  IS+ +L    LEVTV     F S+
Sbjct: 384  KRKTSIIKDNCNPVYDASFEYL-ISISELRHTELEVTVCTQKGFLSS 247
>26525
          Length = 455

 Score = 41.6 bits (96), Expect(2) = 3e-05,   Method: Compositional matrix adjust.
 Identities = 23/75 (30%), Positives = 42/75 (56%), Gaps = 1/75 (1%)
 Frame = +1

Query: 4646 NLVPRD-NNGYSDPFVKVYLLPGRGQVMVVQNASVEYKRRTKYVQKSLNPEWNQTVIYKS 4704
            +L PRD + G  DP+VK+ LLP +           ++K +T+ V+K+LNP++++T  +  
Sbjct: 1    DLPPRDPSLGGCDPYVKLQLLPEK-----------KHKCKTRVVRKTLNPKYDETFTFFG 147

Query: 4705 ISMEQLMKKTLEVTV 4719
            ++  Q+   TL    
Sbjct: 148  VNANQMGSITLHFAC 192

 Score = 27.3 bits (59), Expect(2) = 3e-05,   Method: Compositional matrix adjust.
 Identities = 11/23 (47%), Positives = 16/23 (69%)
 Frame = +3

Query: 4719 VWDYDRFSSNDFLGEVLIDLSST 4741
            V  +DRFS ++ +GEV+  LS T
Sbjct: 189  VLSFDRFSRDEIIGEVIYPLSDT 257
>30040
          Length = 652

 Score = 49.3 bits (116), Expect = 4e-05,   Method: Composition-based stats.
 Identities = 31/100 (31%), Positives = 57/100 (57%)
 Frame = -3

Query: 4637 LIIHILQARNLVPRDNNGYSDPFVKVYLLPGRGQVMVVQNASVEYKRRTKYVQKSLNPEW 4696
            L + +++A++L    ++  +DPFV+V LL        V+   V+ +++T   + S+NP W
Sbjct: 611  LTVVLMKAKDLKMSTSHPSADPFVRVSLL--------VEGKKVK-RKKTSVRRASINPVW 459

Query: 4697 NQTVIYKSISMEQLMKKTLEVTVWDYDRFSSNDFLGEVLI 4736
            N+ + + ++  E L K TLEV+V D+D     D LG  ++
Sbjct: 458  NEALAF-NVPAEVLPKVTLEVSVLDHDLIGHGDVLGTCVL 342
>20073
          Length = 582

 Score = 46.2 bits (108), Expect = 3e-04,   Method: Composition-based stats.
 Identities = 28/86 (32%), Positives = 45/86 (52%)
 Frame = +3

Query: 4440 GLGIRIVGGKEIPGHSGEIGAYIAKILPGGSAEHSGKLIEGMQVLEWNGIPLTSKTYEEV 4499
            GLG  ++GGKE    S  I  YI++I+PGG A+    L  G Q+L  NG+ +  + +E+ 
Sbjct: 3    GLGFNVMGGKE---QSSPI--YISRIIPGGVADRLNCLKRGDQLLSVNGVSVEGEYHEKA 167

Query: 4500 QSIINQQSGEAEICVRLDLNMLSDSE 4525
              ++    G   + VR    +L + E
Sbjct: 168  VELLKLAQGSVRLVVRYTPQILEEME 245
>01494
          Length = 2122

 Score = 41.6 bits (96), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 33/124 (26%), Positives = 58/124 (46%)
 Frame = +1

Query: 4610 KPTDVSKTASHPITGEIQLQINYDLGNLIIHILQARNLVPRDNNGYSDPFVKVYLLPGRG 4669
            KP  ++  A  P   +   Q+  +   L + I+ AR+LV +   G + PFV++       
Sbjct: 1084 KPAIMNHDAFSPYEKKFLSQLGVEPLTLTLTIVGARHLV-KSGRGIASPFVEI------- 1239

Query: 4670 QVMVVQNASVEYKRRTKYVQKSLNPEWNQTVIYKSISMEQLMKKTLEVTVWDYDRFSSND 4729
            +V   +  + ++K  T+ V   LNP WN+  ++  +  E  +   L   V D D F   +
Sbjct: 1240 EVTGXECDNQKFKTGTR-VDNGLNPVWNENCVFDVLCPEMAL---LRFAVMDEDIFGDPN 1407

Query: 4730 FLGE 4733
            FLG+
Sbjct: 1408 FLGQ 1419
>14539
          Length = 436

 Score = 36.2 bits (82), Expect = 0.35,   Method: Composition-based stats.
 Identities = 24/90 (26%), Positives = 45/90 (50%)
 Frame = +3

Query: 4644 ARNLVPRDNNGYSDPFVKVYLLPGRGQVMVVQNASVEYKRRTKYVQKSLNPEWNQTVIYK 4703
            AR+LV +   G + PF+++       ++  ++  + ++K  T+ V   LNP WN+  ++ 
Sbjct: 45   ARHLV-KSGRGIASPFLEI-------EIAGIECDNQKFKTETR-VDNGLNPVWNKNCVFD 197

Query: 4704 SISMEQLMKKTLEVTVWDYDRFSSNDFLGE 4733
             +  E  +   L   V D D F   +FLG+
Sbjct: 198  VLCPELAL---LRFAVMDEDTFGDPNFLGQ 278
>25445
          Length = 460

 Score = 27.7 bits (60), Expect(2) = 2.2,   Method: Compositional matrix adjust.
 Identities = 11/20 (55%), Positives = 14/20 (70%)
 Frame = -3

Query: 4647 LVPRDNNGYSDPFVKVYLLP 4666
            L P D NG +DP+ KV L+P
Sbjct: 152  LCPMDPNGLADPYTKVKLIP 93

 Score = 24.3 bits (51), Expect(2) = 2.2,   Method: Composition-based stats.
 Identities = 8/18 (44%), Positives = 14/18 (77%)
 Frame = -1

Query: 4682 KRRTKYVQKSLNPEWNQT 4699
            +  TK ++ SLNP+W++T
Sbjct: 76   QTETKTIKSSLNPQWDET 23
>30297
          Length = 822

 Score = 32.0 bits (71), Expect = 6.4,   Method: Composition-based stats.
 Identities = 28/103 (27%), Positives = 46/103 (44%)
 Frame = -3

Query: 4341 GYDRDIAFIMDDFQHAMSDSEAYHLRREETDWFDKPRESRLENGHGLDRKLPERLVHSRP 4400
            G+DR I    D    ++SDS  +H++     W D  R+   E+   +   LP  L     
Sbjct: 808  GWDRRINIYYD----SLSDSNIHHVQHPVPYWADDERDGHKEDVLAVAHCLPNLLA---- 653

Query: 4401 LSQHQEQILQMNGKTMHYIFPHARIKITRDSKDHTVSGNGLGI 4443
             + +  +++  N  + H IF H R     D  D ++ G+ LGI
Sbjct: 652  TASYDGEVIVWNMVSGH-IFCHLRPPPPADYTDQSLDGD-LGI 530
>26047
          Length = 430

 Score = 31.6 bits (70), Expect = 8.3,   Method: Composition-based stats.
 Identities = 15/56 (26%), Positives = 23/56 (41%)
 Frame = -3

Query: 993  PKPACPLCRTELNVGSQDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQ 1048
            P+  C  C   +  G  DP     C EC N     C   P   + ++ +W C +C+
Sbjct: 338  PRRKCKHCACCVCGGKNDPGMQLMCDECDNAYHLACLNPPLSAIPDVDDWYCPDCK 171
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|190684703|ref|NP_036010.2| regulator of G protein
signaling 7 [Mus musculus]
         (469 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

28964                                                                  73   2e-13
17291                                                                  47   2e-05
19559                                                                  38   0.007
>28964
          Length = 433

 Score = 73.2 bits (178), Expect = 2e-13,   Method: Compositional matrix adjust.
 Identities = 43/114 (37%), Positives = 61/114 (53%), Gaps = 8/114 (7%)
 Frame = +1

Query: 352 ESEFSSENLRFWLAVE--------DLKRRPIREVPSRVQEIWQEFLAPGAPSAINLDSKS 403
           E EFS EN+ FW AVE        DL+RR       R  EI+   L P A   +N+DS +
Sbjct: 70  EKEFSEENIVFWTAVESYKHIIDEDLRRR-------RAGEIYSSHLGPQASDPVNVDSTA 228

Query: 404 YDKTTQNVKEPGRYTFEDAQEHIYKLMKSDSYPRFIRSSAYQELLQAKRKGKTL 457
              T Q +  P    F+ AQ  I++LM++DSY RF++S  Y+  L  + +G+ L
Sbjct: 229 RQLTEQYLDNPTPNMFDVAQHQIFQLMRTDSYSRFLKSDLYKGYLMREMEGQPL 390
>17291
          Length = 479

 Score = 46.6 bits (109), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 20/32 (62%), Positives = 25/32 (78%)
 Frame = -2

Query: 416 RYTFEDAQEHIYKLMKSDSYPRFIRSSAYQEL 447
           R+TF  AQEHI+ LMK DSY RF+RS  Y++L
Sbjct: 475 RFTFLAAQEHIFLLMKKDSYARFLRSDHYKQL 380
>19559
          Length = 805

 Score = 38.1 bits (87), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 34/121 (28%), Positives = 54/121 (44%), Gaps = 5/121 (4%)
 Frame = -3

Query: 329 RWGFGMDEALKDPVGREQFLKFLESE-FSSENLRFWLAVEDLKRRP---IREVPSRVQEI 384
           RW   +D  L D  G   F K+LE E    + L FW A + LKRR      +V + V+ I
Sbjct: 527 RWAKDLDYLLSDSEGVAVFRKYLEQEQGGCDELHFWFACQGLKRRADSGTVDVMNSVRVI 348

Query: 385 WQEFLAPGAPSAINLDSKSYDKTTQNVKEP-GRYTFEDAQEHIYKLMKSDSYPRFIRSSA 443
           ++ ++      +I+  +K       N K    +  F+ AQ  +   ++  SY  F+ S  
Sbjct: 347 FKTYVRCDKVRSISRATKRDIVDKLNKKSTVDQCVFDKAQXEVEAHLRHVSYLGFLNSDE 168

Query: 444 Y 444
           Y
Sbjct: 167 Y 165
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6678493|ref|NP_033488.1| ubiquitin specific peptidase
10 [Mus musculus]
         (793 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

11884                                                                  74   2e-13
08419                                                                  55   7e-08
35122                                                                  37   0.039
04261                                                                  35   0.12 
29016                                                                  32   1.1  
09980                                                                  30   3.1  
>11884
          Length = 952

 Score = 74.3 bits (181), Expect = 2e-13,   Method: Compositional matrix adjust.
 Identities = 56/200 (28%), Positives = 97/200 (48%), Gaps = 5/200 (2%)
 Frame = +3

Query: 595 TPITGIFGGHIRSVVY-QQSSKESATLQLFFTLQLDIQSDKIRTVQDALESLVARESVQG 653
           T I  +FGG +RS V   +    S T + F  L L+++   + TV+ AL   V  E++  
Sbjct: 6   TVIHQVFGGFLRSQVQCLKCGARSNTFEPFMDLSLNLKD--VNTVEAALGKYVKPETLDA 179

Query: 654 YTT----KTKQEVEVSRRVTLEKLPPVLVLHLKRFVYEKTGGCQKLVKNIDYPVDLEISR 709
                  K +++ +  +R +L K+P VL + L RF + +  G  K+ K+I +P  L + R
Sbjct: 180 ANAYDCQKCRKKTQARKRFSLHKIPNVLTIQLNRFGFTRAAG--KINKHIQFPEKLNV-R 350

Query: 710 ELLSPGIKNKNFKCQRTYRLFAVVYHHGNSATGGHYTTDVFQIGLNGWLRIDDQTVKVIN 769
           + +S    +  +     Y L+ V+ H G+    GHY   V +   N W  ++D +V  ++
Sbjct: 351 QYMSRRQGDPEY-----YHLYGVLIHSGHHCNMGHYYCYV-RSPANSWYIMNDSSVHQVS 512

Query: 770 QYQVVKPPADRTAYLLYYRR 789
             +V        AYLL+Y +
Sbjct: 513 ASRVF----GSQAYLLFYTK 560
>08419
          Length = 731

 Score = 55.5 bits (132), Expect = 7e-08,   Method: Compositional matrix adjust.
 Identities = 40/142 (28%), Positives = 66/142 (46%), Gaps = 15/142 (10%)
 Frame = +1

Query: 663 EVSRRVTLEKLPPVLVLHLKRFVYEKTGGCQKLVK----------NI-DYPVDLEISRE- 710
           ++ RR  L +LP  L++ L RF Y    GC   ++          N+ D   D    RE 
Sbjct: 106 DIQRRCLLSQLPECLIIQLMRFQYNAQQGCSTKLRAPVSIRLKGLNLQDLMCDTVTQRED 285

Query: 711 LLSPGIKNKNFKCQRTYRLFAVVYHHGNSATG-GHYTTDVFQIGLNG-WLRIDDQTVKVI 768
            +SPG  +        Y L+ +  H G  +T  GHY +  + +  +  W R DD+ V  +
Sbjct: 286 CVSPGQNSSQM-----YDLYGLCLHIGADSTHHGHYIS--YSLASDSRWYRYDDEAVTEV 444

Query: 769 N-QYQVVKPPADRTAYLLYYRR 789
           N +Y++      + AY+L+Y+R
Sbjct: 445 NIEYELTTKEVRQNAYILFYKR 510
>35122
          Length = 1031

 Score = 36.6 bits (83), Expect = 0.039,   Method: Compositional matrix adjust.
 Identities = 16/31 (51%), Positives = 20/31 (64%)
 Frame = -3

Query: 409 PRGLINKGNWCYINATLQALVACPPMYHLMK 439
           P GL N GN CY+NAT+Q L A P +   +K
Sbjct: 771 PAGLANLGNTCYMNATIQCLRAVPELRDALK 679
>04261
          Length = 1792

 Score = 35.0 bits (79), Expect = 0.12,   Method: Compositional matrix adjust.
 Identities = 18/71 (25%), Positives = 37/71 (52%)
 Frame = +2

Query: 637 TVQDALESLVARESVQGYTTKTKQEVEVSRRVTLEKLPPVLVLHLKRFVYEKTGGCQKLV 696
           +++DA+++    E ++       Q  +       +KLP +L+L+LKRF Y+  G   K++
Sbjct: 371 SLKDAVKNYFKTEEIEYSCEFCHQHTKAELSSRFKKLPRILILYLKRFEYK--GKMSKIL 544

Query: 697 KNIDYPVDLEI 707
           K +  P  + +
Sbjct: 545 KPLSLPAFISV 577
>29016
          Length = 550

 Score = 32.0 bits (71), Expect = 1.1,   Method: Composition-based stats.
 Identities = 19/54 (35%), Positives = 29/54 (53%), Gaps = 2/54 (3%)
 Frame = +1

Query: 428 LVACPPMYHLM--KFIPLYSKVQRPCTSTPMIDSFVRLMNEFTNMPVPPKPRQA 479
           LV+CP  +H+     IP    V   C +  + DS+    + FTN+P PP PR++
Sbjct: 142 LVSCPAEFHVECGANIP---GVLVDCAAEQVDDSWCSAGDGFTNLPCPPIPRRS 294
>09980
          Length = 459

 Score = 30.4 bits (67), Expect = 3.1,   Method: Composition-based stats.
 Identities = 17/47 (36%), Positives = 25/47 (53%), Gaps = 8/47 (17%)
 Frame = +1

Query: 404 PVSLQPRGLIN--KGNWCYINATLQALV------ACPPMYHLMKFIP 442
           P+  +P G +   K +  YIN  L +LV       C PMY ++KF+P
Sbjct: 31  PLYCEPSGKLTTLKSSLSYINNLLSSLVYF*SEKECSPMYIVLKFVP 171
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6679389|ref|NP_032907.1| plexin A1 [Mus musculus]
         (1894 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

38765                                                                  75   2e-13
27845                                                                  62   2e-09
35046                                                                  47   6e-05
33760                                                                  38   0.031
28520                                                                  34   0.59 
07382                                                                  32   3.0  
27299                                                                  30   7.0  
17589                                                                  30   8.4  
>38765
          Length = 756

 Score = 75.1 bits (183), Expect = 2e-13,   Method: Compositional matrix adjust.
 Identities = 70/263 (26%), Positives = 113/263 (42%), Gaps = 19/263 (7%)
 Frame = +3

Query: 101 SCPHGLGSTDNVNKXXXXXXXXXXXXXCGSASQGICQFLRLDDLFKLGEPHHRKEHY--- 157
           +C  G  STDN NK             CGS  QG C+   L ++       H +E+Y   
Sbjct: 3   ACNTGRTSTDNYNKILLLDHAQRMLITCGSVYQGACETRSLANI------SHVQEYYSAD 164

Query: 158 -------LSSVREAGSMAGVLIAGPPGQGQAKLFVGTPIDGKS-------EYFPTLSSRR 203
                   ++ R A ++A   IA      Q+ L+V     G+S       +  P LSSR 
Sbjct: 165 DVTDFAVAANSRNASTVA--FIAPGSTHSQSVLYVAATYTGRSRTSRIYRDQVPALSSRS 338

Query: 204 LMANEEDADMFGFVYQDEFVSSQLKIPSDTLSKFPAFDIYYVYSFRSEQFVYYXXXXXXX 263
           L   +    +         +SS + + S+  S F    I YV +F  + F Y+       
Sbjct: 339 LK-KQRPFSLAAVSNPLRGMSSSIYLKSEISSYFL---IRYVTAFSYQGFSYFLTVQND- 503

Query: 264 XXXSPDAAGEHFFTSKIVRLCVNDPKFYSYVEFPIGCEQAGVEYRLVQDAYLSRPGQALA 323
              S +    +   SKIV++C +D  F+SY + PI C + GV+Y +++ A +  PG  L 
Sbjct: 504 ---SVEDRATNKKVSKIVQICQDDSNFFSYADIPIKCIKDGVDYNVLEAAQIISPGLRLR 674

Query: 324 KQLGLAE--DEEVLFTVFAQGQK 344
           + LG  +   +E+L   F++  +
Sbjct: 675 ESLGYLDGFTDEILVAAFSRADE 743
>27845
          Length = 384

 Score = 62.0 bits (149), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 28/77 (36%), Positives = 40/77 (51%)
 Frame = +1

Query: 615 CHSPSAREVAPITQGQGDQRVVKLYLKSKETGKKFASVDFVFYNCSVHQSCLACVNGSFP 674
           C +P+ + +      +   R V L L S ETGK F +  F FYNCS   +C  C + +F 
Sbjct: 118 CSTPNFQRLGLSLGTEAGFRTVTLALNSTETGKLFVTKSFTFYNCSNFNTCSQCTDSAFE 297

Query: 675 CHWCKYRHVCTNNAADC 691
           CHWC Y + C ++   C
Sbjct: 298 CHWCVYDNGCYHDTMAC 348
>35046
          Length = 518

 Score = 47.4 bits (111), Expect = 6e-05,   Method: Compositional matrix adjust.
 Identities = 36/116 (31%), Positives = 52/116 (44%), Gaps = 8/116 (6%)
 Frame = -1

Query: 1044 EDPTILRIDPEWSINSXXXXXXXXXXXXXXVREPRIRAKYGGIERENSCMVYNDTTMVCR 1103
            +DP I  I+P+ SI S              ++ P     YGG      C + N  TM C+
Sbjct: 404  KDPEITMIEPKKSILSGGTLITVLGARLDLIQRPEFFVTYGGQFHTQMCRLENTYTMECQ 225

Query: 1104 APSIDNP-KRSPPELGE-RPDEI--GFIMDNVRTLLVLNSSS----FLYYPDPVLE 1151
             PS+ N  + S   + E  P E+  GF +D V TL  ++  +     L YPDP L+
Sbjct: 224  VPSLQNAIQTSGTNITETSPLEVHYGFTLDGVTTLKNISHEAKFGPLLLYPDPTLK 57
>33760
          Length = 495

 Score = 38.1 bits (87), Expect = 0.031,   Method: Composition-based stats.
 Identities = 23/73 (31%), Positives = 36/73 (49%), Gaps = 3/73 (4%)
 Frame = -1

Query: 497 LYAMTEKQVTQVPVESCVQYTSCELCLGSRDPHCGWCVLHSICSRQDACERA---EEPQR 553
           LY  T++ V Q+ V +C  Y   +LC+   DP+CGW    ++C       RA    +   
Sbjct: 288 LYLGTDQSVVQLGVITCEVYLKVDLCV--YDPYCGWDAKTNLCVPATKGRRAITFADIDL 115

Query: 554 FASDLLQCVQLTV 566
           +  DL + +QL V
Sbjct: 114 YNHDLERAIQLKV 76
>28520
          Length = 446

 Score = 33.9 bits (76), Expect = 0.59,   Method: Compositional matrix adjust.
 Identities = 28/104 (26%), Positives = 47/104 (45%), Gaps = 6/104 (5%)
 Frame = +2

Query: 435 VAAYDYQGRTVVFAGTRSGRIRKILVDLANPSGRPALAYESV-VAQEGNPI-----LRDL 488
           V A D +   V+F GT  GR+ K  V+    S    +  E + V  E +P+      RD 
Sbjct: 128 VKAADDRYYDVMFVGTDDGRVIK-AVNKGQSSQIETVVIEDIRVFGEHDPVTDLKVFRDT 304

Query: 489 VLSPNRQYLYAMTEKQVTQVPVESCVQYTSCELCLGSRDPHCGW 532
             +   + L  ++ ++V +    + V   +C  C+  RDP+C W
Sbjct: 305 --AKGIEQLVVISREEVGRPSPSTAVAQETCRACVELRDPYCVW 430
>07382
          Length = 1486

 Score = 31.6 bits (70), Expect = 3.0,   Method: Compositional matrix adjust.
 Identities = 12/25 (48%), Positives = 17/25 (68%)
 Frame = -3

Query: 1008 EIRCLTPPGHTPGSAPIVININRAQ 1032
            + RC TPP  +PG+ P +I +NR Q
Sbjct: 161  QWRCQTPPSWSPGAGPPLIRLNRRQ 87
>27299
          Length = 864

 Score = 30.4 bits (67), Expect = 7.0,   Method: Compositional matrix adjust.
 Identities = 14/33 (42%), Positives = 18/33 (54%)
 Frame = -3

Query: 862 PKILKLSPETGPRQGGTRLTITGENLGLRFEDV 894
           P +  L P      GGTRL + G+NLGL   D+
Sbjct: 841 PIVTNLIPNMATVHGGTRLCVEGKNLGLGKSDI 743
>17589
          Length = 456

 Score = 30.0 bits (66), Expect = 8.4,   Method: Compositional matrix adjust.
 Identities = 15/28 (53%), Positives = 17/28 (60%)
 Frame = +1

Query: 861 DPKILKLSPETGPRQGGTRLTITGENLG 888
           DP I  + P    RQGG  LTITG +LG
Sbjct: 196 DPVITNILPLASIRQGGRMLTITGTDLG 279
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6680954|ref|NP_031753.1| contactin 1 [Mus musculus]
         (1020 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

35419                                                                  54   2e-13
29990                                                                  63   5e-10
19544                                                                  59   1e-08
13135                                                                  59   1e-08
25766                                                                  42   2e-07
25455                                                                  53   5e-07
36700                                                                  53   6e-07
08294                                                                  50   5e-06
27666                                                                  50   6e-06
20110                                                                  47   5e-05
17229                                                                  47   6e-05
11788                                                                  45   2e-04
38127                                                                  45   2e-04
11855                                                                  44   2e-04
06028                                                                  44   3e-04
17679                                                                  40   0.004
18345                                                                  39   0.010
34369                                                                  37   0.060
36498                                                                  33   0.63 
20244                                                                  30   0.65 
03196                                                                  32   1.3  
05835                                                                  25   1.8  
22019                                                                  31   2.5  
32888                                                                  31   2.7  
04905                                                                  31   3.1  
11767                                                                  30   4.8  
29932                                                                  30   5.1  
>35419
          Length = 623

 Score = 53.5 bits (127), Expect(2) = 2e-13,   Method: Compositional matrix adjust.
 Identities = 40/148 (27%), Positives = 71/148 (47%), Gaps = 2/148 (1%)
 Frame = -2

Query: 492 KANSTGTLVITNPTRIILAPINADITVGENATMQCAASFDP--ALDLTFVWSFNGYVIDF 549
           K +++G L++   T+I  AP++ ++  G +A   C+ + DP     L   W      +  
Sbjct: 613 KTSASGVLLVRRKTQIEQAPMDLEVNAGTDAKFTCSGTTDPEEVHMLKIKW------MKD 452

Query: 550 NKEITHIHYQRNFMLDANGELLIRNAQLKHAGRYTCTAQTIVDNSSASADLVVRXXXXXX 609
           NKEI+ +  +    +  N  L I    ++ +G YTC +   +D++ ASA L V+      
Sbjct: 451 NKEISTVEQRMTTNIQDNS-LTISGTIVRDSGTYTCISTNGLDSAEASAMLTVKDRPDVA 275

Query: 610 XXLRIEDIRATSVALTWSRGSDNHSPIS 637
             ++IE     +  L W  GS N++P S
Sbjct: 274 SEVKIEKCDDNATIL-WMPGSYNNAPSS 194

 Score = 40.8 bits (94), Expect(2) = 2e-13,   Method: Compositional matrix adjust.
 Identities = 22/64 (34%), Positives = 34/64 (53%), Gaps = 1/64 (1%)
 Frame = -1

Query: 635 PISKYTIQTKTILS-DDWKDAKTDPPIIEGNMESAKAVDLIPWMEYEFRVVATNTLGTGE 693
           P+  Y IQ  T  + D W  A     +   ++ ++  V L PW+ Y FRV+A N +G  +
Sbjct: 203 PVQYYVIQYNTSFNPDTWTFA-----VQVDSIFTSANVSLSPWVNYTFRVIAYNKIGESD 39

Query: 694 PSIP 697
           PS+P
Sbjct: 38  PSLP 27
>29990
          Length = 434

 Score = 63.2 bits (152), Expect = 5e-10,   Method: Composition-based stats.
 Identities = 36/114 (31%), Positives = 55/114 (48%), Gaps = 14/114 (12%)
 Frame = +3

Query: 356 GKPIPTIRWLKNGYS-----------YHKGELRLYDVTFENAGMYQCIAENAYGSIYAN- 403
           GKP+P I W+ N               H G L + D   ++ G+Y+CIA N  G  ++N 
Sbjct: 6   GKPVPEIVWMHNNNRVEISGDSRFSLLHDGTLMIEDAQDDDRGVYECIARNVAGETHSNQ 185

Query: 404 AELKILA--LAPTFEMNPMKKKILAAKGGRVIIECKPKAAPKPKFSWSKGTEWL 455
            EL+     +AP F   P  + I+  +G  V + C+    P+P FSW++  E L
Sbjct: 186 VELRYFGERVAPXFTQRP--QDIVTVEGQTVQLVCQASGHPRPTFSWTRNLEQL 341

 Score = 49.7 bits (117), Expect(2) = 2e-06,   Method: Composition-based stats.
 Identities = 37/117 (31%), Positives = 53/117 (45%), Gaps = 3/117 (2%)
 Frame = +3

Query: 172 WLLNEFPVFITMDKRRFVSQTNGNLYIANVESSDRGNYSCF---VSSPSITKSVFSKFIP 228
           W+ N   V I+ D R F    +G L I + +  DRG Y C    V+  + +  V  ++  
Sbjct: 30  WMHNNNRVEISGDSR-FSLLHDGTLMIEDAQDDDRGVYECIARNVAGETHSNQVELRYFG 206

Query: 229 LIPIPERTTKPYPADIVVQFKDIYTMMGQNVTLECFALGNPVPDIRWRKVLEPMPST 285
               P  T +P         +DI T+ GQ V L C A G+P P   W + LE + ST
Sbjct: 207 ERVAPXFTQRP---------QDIVTVEGQTVQLVCQASGHPRPTFSWTRNLEQLGST 350

 Score = 21.2 bits (43), Expect(2) = 2e-06,   Method: Composition-based stats.
 Identities = 9/20 (45%), Positives = 11/20 (55%)
 Frame = +2

Query: 293 AVLKIFNIQLEDEGLYECEA 312
             L I N+Q  D G Y+C A
Sbjct: 374 GTLTIRNVQESDRGDYQCYA 433

 Score = 36.6 bits (83), Expect(2) = 6e-06,   Method: Composition-based stats.
 Identities = 19/63 (30%), Positives = 31/63 (49%), Gaps = 1/63 (1%)
 Frame = +3

Query: 71  PFPVYKWRMNNGDVDLTND-RYSMVGGNLVINNPDKQKDAGVYYCLASNNYGMVRSTEAT 129
           P P   W  NN  V+++ D R+S++    ++    +  D GVY C+A N  G   S +  
Sbjct: 12  PVPEIVWMHNNNRVEISGDSRFSLLHDGTLMIEDAQDDDRGVYECIARNVAGETHSNQVE 191

Query: 130 LSF 132
           L +
Sbjct: 192 LRY 200

 Score = 32.3 bits (72), Expect(2) = 6e-06,   Method: Composition-based stats.
 Identities = 19/56 (33%), Positives = 27/56 (48%)
 Frame = +2

Query: 157 LCDPPYHFPDDLSYRWLLNEFPVFITMDKRRFVSQTNGNLYIANVESSDRGNYSCF 212
           L  PP H          L++ P  + +D R      +G L I NV+ SDRG+Y C+
Sbjct: 290 LRSPPPHLQ--------LDQEPRAVGLDPR-ITDHEDGTLTIRNVQESDRGDYQCY 430

 Score = 35.8 bits (81), Expect(2) = 0.009,   Method: Composition-based stats.
 Identities = 33/113 (29%), Positives = 47/113 (41%), Gaps = 8/113 (7%)
 Frame = +3

Query: 439 KAAPKPKFSWSKGTEW--LVNSSRILIWEDGSLEINNITRNDGGIYTCFAENNRGKANST 496
           +  P P+  W        +   SR  +  DG+L I +   +D G+Y C A N  G+ +S 
Sbjct: 3   EGKPVPEIVWMHNNNRVEISGDSRFSLLHDGTLMIEDAQDDDRGVYECIARNVAGETHSN 182

Query: 497 GTLVITNPTRIILAPI----NADITVGENATMQ--CAASFDPALDLTFVWSFN 543
              +     R+  AP       DI   E  T+Q  C AS  P    TF W+ N
Sbjct: 183 QVELRYFGERV--APXFTQRPQDIVTVEGQTVQLVCQASGHPR--PTFSWTRN 329

 Score = 22.3 bits (46), Expect(2) = 0.009,   Method: Composition-based stats.
 Identities = 10/21 (47%), Positives = 11/21 (52%)
 Frame = +2

Query: 567 NGELLIRNAQLKHAGRYTCTA 587
           +G L IRN Q    G Y C A
Sbjct: 371 DGTLTIRNVQESDRGDYQCYA 433

 Score = 30.0 bits (66), Expect = 5.6,   Method: Composition-based stats.
 Identities = 15/46 (32%), Positives = 22/46 (47%)
 Frame = +2

Query: 441 APKPKFSWSKGTEWLVNSSRILIWEDGSLEINNITRNDGGIYTCFA 486
           +P P     +    +    RI   EDG+L I N+  +D G Y C+A
Sbjct: 296 SPPPHLQLDQEPRAVGLDPRITDHEDGTLTIRNVQESDRGDYQCYA 433
>19544
          Length = 1421

 Score = 58.9 bits (141), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 45/139 (32%), Positives = 63/139 (45%), Gaps = 4/139 (2%)
 Frame = +2

Query: 779 STAFQVKVKAFNNKGDGPYSLVAVINSAQDAPSEAPTEVGVKVLSSSEISVHW----KHV 834
           S  ++V+V A N KG GP S  A I   + AP+E P+ V     S+S I V W       
Sbjct: 11  SQTYEVQVLAVNGKGRGPPSTPATIYVGEAAPTEGPSNVQAVNKSASSIQVTWVAPPPET 190

Query: 835 LEKIVESYQIRYWAGHDKEAAAHRVQVTSQEYSARLENLLPDTQYFIEVGACNSAGCGPS 894
               +  Y++ Y+      +A   +   + E    LE+L   T YFI V   N AG GP 
Sbjct: 191 QNGGLSGYKVLYY--KQSSSAEEELTRITAETHILLESLETFTVYFIAVQPYNLAGEGPR 364

Query: 895 SDVIETFTRKAPPSQPPRI 913
           S ++   T +  PS P  I
Sbjct: 365 SALVSAQTSEGVPSAPQSI 421

 Score = 54.3 bits (129), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 42/159 (26%), Positives = 71/159 (44%)
 Frame = +2

Query: 673 LIPWMEYEFRVVATNTLGTGEPSIPSNRIKTDGAAPNVAPSDVGGGGGTNRELTITWAPL 732
           L+    YE +V+A N  G G PS P+  I    AAP   PS+V     +   + +TW   
Sbjct: 2   LVISQTYEVQVLAVNGKGRGPPSTPAT-IYVGEAAPTEGPSNVQAVNKSASSIQVTWVAP 178

Query: 733 SREYHYGNNFGYIVAFKPFDGEEWKKVTVTNPDTGRYVHKDETMTPSTAFQVKVKAFNNK 792
             E   G   GY V +        +++T    +T   +   ET    T + + V+ +N  
Sbjct: 179 PPETQNGGLSGYKVLYYKQSSSAEEELTRITAETHILLESLETF---TVYFIAVQPYNLA 349

Query: 793 GDGPYSLVAVINSAQDAPSEAPTEVGVKVLSSSEISVHW 831
           G+GP S +    +++  PS AP  +    ++  ++ VH+
Sbjct: 350 GEGPRSALVSAQTSEGVPS-APQSIRFTNITMRQLMVHF 463

 Score = 35.8 bits (81), Expect = 0.097,   Method: Compositional matrix adjust.
 Identities = 22/75 (29%), Positives = 37/75 (49%), Gaps = 1/75 (1%)
 Frame = +2

Query: 873 LLPDTQYFIEVGACNSAGCGPSSDVIETFTRKAPPSQPPRIISSV-RSGSRYIITWDHVV 931
           L+    Y ++V A N  G GP S     +  +A P++ P  + +V +S S   +TW    
Sbjct: 2   LVISQTYEVQVLAVNGKGRGPPSTPATIYVGEAAPTEGPSNVQAVNKSASSIQVTWVAPP 181

Query: 932 ALSNESTVTGYKILY 946
             +    ++GYK+LY
Sbjct: 182 PETQNGGLSGYKVLY 226
>13135
          Length = 849

 Score = 58.5 bits (140), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 43/165 (26%), Positives = 81/165 (49%), Gaps = 14/165 (8%)
 Frame = -1

Query: 295 LKIFNIQLEDEGLYECEAENIRGKDKHQARIYVQAFPEWVEHIND--TEVDI----GSDL 348
           L+I N Q+ DEG+Y C+   ++  +++ A+ + Q     +  I+D  T  D+    G  L
Sbjct: 495 LRIQNGQVTDEGVYTCQ---VQLSNQNYAKAFHQLVIIQMPQISDLDTSSDVSKSEGQSL 325

Query: 349 YWPCIATGKPIPTIRWLK--------NGYSYHKGELRLYDVTFENAGMYQCIAENAYGSI 400
              C A+G+P P+++W +         G  + + +L +  +  E+AG+Y+C + N+ GS 
Sbjct: 324 VLRCHASGRPTPSVKWTRMAGELLPSGGREHLESDLVIPQLKPEHAGIYKCSSSNSAGSD 145

Query: 401 YANAELKILALAPTFEMNPMKKKILAAKGGRVIIECKPKAAPKPK 445
           + N  + +   AP   ++     +  A+G    + C  K  P PK
Sbjct: 144 FRNIRVTV-NFAPV--LSSANTVVQQAQGYVKELVCVVKGYPTPK 19

 Score = 48.5 bits (114), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 47/173 (27%), Positives = 72/173 (41%), Gaps = 2/173 (1%)
 Frame = -1

Query: 190 SQTNGNLYIANVESSDRGNYSCFVSSPSITKSVFSK-FIPLIPIPERTTKPYPADIVVQF 248
           S T+  L I N + +D G Y+C V    ++   ++K F  L+ I      P  +D+    
Sbjct: 513 SPTSWRLRIQNGQVTDEGVYTCQVQ---LSNQNYAKAFHQLVII----QMPQISDLDTS- 358

Query: 249 KDIYTMMGQNVTLECFALGNPVPDIRW-RKVLEPMPSTAEISTSGAVLKIFNIQLEDEGL 307
            D+    GQ++ L C A G P P ++W R   E +PS          L I  ++ E  G+
Sbjct: 357 SDVSKSEGQSLVLRCHASGRPTPSVKWTRMAGELLPSGGREHLESD-LVIPQLKPEHAGI 181

Query: 308 YECEAENIRGKDKHQARIYVQAFPEWVEHINDTEVDIGSDLYWPCIATGKPIP 360
           Y+C + N  G D    R+ V   P         +   G      C+  G P P
Sbjct: 180 YKCSSSNSAGSDFRNIRVTVNFAPVLSSANTVVQQAQGYVKELVCVVKGYPTP 22

 Score = 33.9 bits (76), Expect = 0.31,   Method: Compositional matrix adjust.
 Identities = 27/119 (22%), Positives = 53/119 (44%), Gaps = 3/119 (2%)
 Frame = -1

Query: 376 LRLYDVTFENAGMYQCIAENAYGSIYANA--ELKILALAPTFEMNPMKKKILAAKGGRVI 433
           LR+ +    + G+Y C  + +  + YA A  +L I+ +    +++     +  ++G  ++
Sbjct: 495 LRIQNGQVTDEGVYTCQVQLSNQN-YAKAFHQLVIIQMPQISDLD-TSSDVSKSEGQSLV 322

Query: 434 IECKPKAAPKPKFSWSK-GTEWLVNSSRILIWEDGSLEINNITRNDGGIYTCFAENNRG 491
           + C     P P   W++   E L +  R  +  D  L I  +     GIY C + N+ G
Sbjct: 321 LRCHASGRPTPSVKWTRMAGELLPSGGREHLESD--LVIPQLKPEHAGIYKCSSSNSAG 151

 Score = 32.3 bits (72), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 25/78 (32%), Positives = 39/78 (50%), Gaps = 2/78 (2%)
 Frame = -1

Query: 58  EGK-VSLNCRARASPFPVYKWRMNNGDVDLTNDRYSMVGGNLVINNPDKQKDAGVYYCLA 116
           EG+ + L C A   P P  KW    G++  +  R  +   +LVI    K + AG+Y C +
Sbjct: 339 EGQSLVLRCHASGRPTPSVKWTRMAGELLPSGGREHL-ESDLVIPQL-KPEHAGIYKCSS 166

Query: 117 SNNYGM-VRSTEATLSFG 133
           SN+ G   R+   T++F 
Sbjct: 165 SNSAGSDFRNIRVTVNFA 112
>25766
          Length = 469

 Score = 41.6 bits (96), Expect(2) = 2e-07,   Method: Compositional matrix adjust.
 Identities = 28/93 (30%), Positives = 45/93 (48%), Gaps = 1/93 (1%)
 Frame = +1

Query: 189 VSQTNGNLYIANVESSDRGNYSCFV-SSPSITKSVFSKFIPLIPIPERTTKPYPADIVVQ 247
           V + +G L I  V ++D G Y C + SS  IT   F+          R + P P  + V+
Sbjct: 46  VREYDGILQIPRVTAADAGRYRCVITSSEGITSEGFATL--------RISSP-PV-VSVK 195

Query: 248 FKDIYTMMGQNVTLECFALGNPVPDIRWRKVLE 280
            ++    +G +V   C   G+PVP +RW K ++
Sbjct: 196 QRNENRQVGSSVKFHCDVSGDPVPQVRWEKKVD 294

 Score = 32.3 bits (72), Expect(2) = 2e-07,   Method: Composition-based stats.
 Identities = 16/46 (34%), Positives = 26/46 (56%)
 Frame = +3

Query: 282 MPSTAEISTSGAVLKIFNIQLEDEGLYECEAENIRGKDKHQARIYV 327
           +P+  +I     +L ++NIQ EDEG Y C A +  G D+  + + V
Sbjct: 297 LPAQHQIRN--GILTLYNIQKEDEGRYICTASSENGVDRDYSNLRV 428

 Score = 32.3 bits (72), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 18/76 (23%), Positives = 33/76 (43%), Gaps = 1/76 (1%)
 Frame = +1

Query: 293 AVLKIFNIQLEDEGLYECEAENIRG-KDKHQARIYVQAFPEWVEHINDTEVDIGSDLYWP 351
            +L+I  +   D G Y C   +  G   +  A + + + P       +    +GS + + 
Sbjct: 61  GILQIPRVTAADAGRYRCVITSSEGITSEGFATLRISSPPVVSVKQRNENRQVGSSVKFH 240

Query: 352 CIATGKPIPTIRWLKN 367
           C  +G P+P +RW K 
Sbjct: 241 CDVSGDPVPQVRWEKK 288
>25455
          Length = 444

 Score = 53.1 bits (126), Expect = 5e-07,   Method: Compositional matrix adjust.
 Identities = 39/152 (25%), Positives = 56/152 (36%), Gaps = 20/152 (13%)
 Frame = +1

Query: 308 YECEAENIRGKDK---HQARIYVQAFPEWVEHINDTEVDIGSDLYWPCIATGKPIPTIRW 364
           Y C AE+          + R+ VQ+ P WV     TEV++G      C AT  P P   W
Sbjct: 1   YRCWAESTVHHINFPLREMRVVVQSAPSWVVAPQVTEVEVGETAEITCNATAIPDPVTNW 180

Query: 365 LKNG-----------------YSYHKGELRLYDVTFENAGMYQCIAENAYGSIYANAELK 407
             NG                 +      L L +VT E   + QC   N YG ++A+  L 
Sbjct: 181 FVNGREISDVVEHDVRFQSGRFDLTSDRLILRNVTIEGRMVVQCNVTNRYGHLWADVSLN 360

Query: 408 ILALAPTFEMNPMKKKILAAKGGRVIIECKPK 439
           +L         PM++  +         E  P+
Sbjct: 361 VLT--------PMQETTITPTSAPSTTEESPQ 432
>36700
          Length = 595

 Score = 53.1 bits (126), Expect = 6e-07,   Method: Compositional matrix adjust.
 Identities = 45/154 (29%), Positives = 62/154 (40%), Gaps = 17/154 (11%)
 Frame = +1

Query: 261 LECFALG------NPVPDIRWRKVLEPMPSTA---EISTSGAVLKIFNIQLEDEGLYECE 311
           LEC   G      N VP I W +      ST     I  +G VL I N+  +DE  Y C+
Sbjct: 19  LECVFSGYSSTPNNQVPAITWWETSTDQISTGGRFSIEDNGRVLVIDNVDEQDEKTYTCK 198

Query: 312 AENIRGKDKHQARIYVQAFPEWVEHINDTEVDIGSDLYWPCI---ATG-KPIPTIRWLKN 367
            EN  G       + V + P +++H+    V  G D Y+ C+   A+G KP     W +N
Sbjct: 199 GENPAGSHSGNLHLNVTSPPIFMQHLQSLTVPQGKDAYFNCVTRSASGEKPPNPPTWYRN 378

Query: 368 GYSYHKGELRLYDVTFEN----AGMYQCIAENAY 397
           G       L    V F      AG   C   + +
Sbjct: 379 GLRLDNTPLSPRQVPFPG*EP*AGHQVCTERHGH 480

 Score = 32.7 bits (73), Expect = 0.69,   Method: Compositional matrix adjust.
 Identities = 21/80 (26%), Positives = 35/80 (43%), Gaps = 1/80 (1%)
 Frame = +1

Query: 448 WSKGTEWLVNSSRILIWEDGS-LEINNITRNDGGIYTCFAENNRGKANSTGTLVITNPTR 506
           W   T+ +    R  I ++G  L I+N+   D   YTC  EN  G  +    L +T+P  
Sbjct: 82  WETSTDQISTGGRFSIEDNGRVLVIDNVDEQDEKTYTCKGENPAGSHSGNLHLNVTSPPI 261

Query: 507 IILAPINADITVGENATMQC 526
            +    +  +  G++A   C
Sbjct: 262 FMQHLQSLTVPQGKDAYFNC 321
>08294
          Length = 1849

 Score = 50.1 bits (118), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 38/127 (29%), Positives = 55/127 (43%), Gaps = 2/127 (1%)
 Frame = +2

Query: 240 YPADIVVQFKDIYTMMGQNVTLECFALGNPVPDIRWRKVLEPMPSTAEIST--SGAVLKI 297
           +PA I V+  +I    G +  L C A G+P PDI W +  +P+   A   T      +KI
Sbjct: 74  WPA-ITVKSNNITVFEGHSAILHCVAKGSPSPDIAWYRDSQPILPNARRYTLFKNGTMKI 250

Query: 298 FNIQLEDEGLYECEAENIRGKDKHQARIYVQAFPEWVEHINDTEVDIGSDLYWPCIATGK 357
             + +ED G+Y C A N  G     +   ++    W      T     S L   C+A   
Sbjct: 251 RQVFMEDNGMYACVANNTAGPLAGTSSFALRTM-HWRRMKTSTW*RPSSSL---CVA--- 409

Query: 358 PIPTIRW 364
           P PT+ W
Sbjct: 410 PAPTLPW 430

 Score = 41.6 bits (96), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 29/115 (25%), Positives = 46/115 (40%), Gaps = 11/115 (9%)
 Frame = +2

Query: 308 YECEAENIR-GKDKHQARIYVQAFPEWVEHINDTEVDIGSDLYWPCIATGKPIPTIRWLK 366
           Y C A + R G       I +  +P      N+  V  G      C+A G P P I W +
Sbjct: 5   YTCVATHPRQGVINATIHISIVEWPAITVKSNNITVFEGHSAILHCVAKGSPSPDIAWYR 184

Query: 367 NG---------YSYHK-GELRLYDVTFENAGMYQCIAENAYGSIYANAELKILAL 411
           +          Y+  K G +++  V  E+ GMY C+A N  G +   +   +  +
Sbjct: 185 DSQPILPNARRYTLFKNGTMKIRQVFMEDNGMYACVANNTAGPLAGTSSFALRTM 349

 Score = 31.2 bits (69), Expect = 2.1,   Method: Compositional matrix adjust.
 Identities = 17/66 (25%), Positives = 31/66 (46%)
 Frame = +2

Query: 63  LNCRARASPFPVYKWRMNNGDVDLTNDRYSMVGGNLVINNPDKQKDAGVYYCLASNNYGM 122
           L+C A+ SP P   W  ++  +     RY++     +       +D G+Y C+A+N  G 
Sbjct: 134 LHCVAKGSPSPDIAWYRDSQPILPNARRYTLFKNGTMKIRQVFMEDNGMYACVANNTAGP 313

Query: 123 VRSTEA 128
           +  T +
Sbjct: 314 LAGTSS 331
>27666
          Length = 873

 Score = 49.7 bits (117), Expect = 6e-06,   Method: Compositional matrix adjust.
 Identities = 36/115 (31%), Positives = 53/115 (46%), Gaps = 14/115 (12%)
 Frame = +1

Query: 295 LKIFNIQLEDEGLYECEA----ENIRGKDKHQARIYVQAFPEWV--EHINDTEVDIGSDL 348
           L I  ++ +D G Y C+     ENI  + +    + VQ  P+    E     E+D   + 
Sbjct: 394 LVIRRLRQQDAGTYVCQVKIQNENILSQVQKIGTLTVQVPPKIRPGETTTLVEIDQNQNS 573

Query: 349 YWPCIATGKPIPTIRW-------LKNGYSYHKG-ELRLYDVTFENAGMYQCIAEN 395
              C +TG P P I W       L  GYS  +G EL L   T ++ G+Y+C+A N
Sbjct: 574 SLVCSSTGIPAPNITWTRLDGRALPTGYSQFRGRELPLNGATVDHMGVYRCVANN 738

 Score = 35.4 bits (80), Expect = 0.12,   Method: Compositional matrix adjust.
 Identities = 33/135 (24%), Positives = 53/135 (39%), Gaps = 3/135 (2%)
 Frame = +1

Query: 196 LYIANVESSDRGNYSCFV--SSPSITKSVFSKFIPLIPIPERTTKPYPADIVVQFKDIYT 253
           L I  +   D G Y C V   + +I   V       + +P +  +P     +V+      
Sbjct: 394 LVIRRLRQQDAGTYVCQVKIQNENILSQVQKIGTLTVQVPPKI-RPGETTTLVEIDQ--- 561

Query: 254 MMGQNVTLECFALGNPVPDIRWRKVLEPMPSTAEISTSGAVLKIFNIQLEDEGLYECEA- 312
              QN +L C + G P P+I W ++      T      G  L +    ++  G+Y C A 
Sbjct: 562 --NQNSSLVCSSTGIPAPNITWTRLDGRALPTGYSQFRGRELPLNGATVDHMGVYRCVAN 735

Query: 313 ENIRGKDKHQARIYV 327
            NI+  D H   + V
Sbjct: 736 NNIKPPDDHLCEVRV 780
>20110
          Length = 820

 Score = 46.6 bits (109), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 38/139 (27%), Positives = 61/139 (43%), Gaps = 3/139 (2%)
 Frame = -1

Query: 196 LYIANVESSDRGNYSCFVSSPSITKSVFSKFIP--LIPIPERTTKPYPADIVVQFKDIYT 253
           L +  +  +D G Y+C V   +++   +   I    + +P  + KP     V+Q +    
Sbjct: 673 LVVRRLVETDAGIYTCTVRITAVSYEEWPTKIGNLTVQVPP-SIKPGDTTAVLQIEQ--- 506

Query: 254 MMGQNVTLECFALGNPVPDIRWRKVLEPMPSTAEISTSGAVLKIFNIQLEDEGLYECEAE 313
             GQN TL C A G P P+I W +               A L + N+ + D G+Y C A+
Sbjct: 505 --GQNSTLVCAASGIPAPNITWTRSDGGFLPIGVAQFRSATLPMNNVTVRDMGVYRCVAD 332

Query: 314 -NIRGKDKHQARIYVQAFP 331
            NI+   +H A + V   P
Sbjct: 331 NNIKPPAEHLAEVLVFHAP 275

 Score = 38.1 bits (87), Expect(2) = 8e-05,   Method: Compositional matrix adjust.
 Identities = 28/127 (22%), Positives = 49/127 (38%), Gaps = 25/127 (19%)
 Frame = -1

Query: 294 VLKIFNIQLEDEGLYECEAENIRGKDKHQARIYVQAFPEWVEHINDTEVDI--------- 344
           +L +  +   D G+Y C             RI   ++ EW   I +  V +         
Sbjct: 676 MLVVRRLVETDAGIYTCTV-----------RITAVSYEEWPTKIGNLTVQVPPSIKPGDT 530

Query: 345 --------GSDLYWPCIATGKPIPTIRWLKN--GY------SYHKGELRLYDVTFENAGM 388
                   G +    C A+G P P I W ++  G+       +    L + +VT  + G+
Sbjct: 529 TAVLQIEQGQNSTLVCAASGIPAPNITWTRSDGGFLPIGVAQFRSATLPMNNVTVRDMGV 350

Query: 389 YQCIAEN 395
           Y+C+A+N
Sbjct: 349 YRCVADN 329

 Score = 27.3 bits (59), Expect(2) = 8e-05,   Method: Compositional matrix adjust.
 Identities = 14/45 (31%), Positives = 21/45 (46%)
 Frame = -3

Query: 431 RVIIECKPKAAPKPKFSWSKGTEWLVNSSRILIWEDGSLEINNIT 475
           R  +EC  K  P+P  +W    E  +N+ R  I +     IN +T
Sbjct: 224 RANLECIVKGHPEPTVTW----EMAINNGRFPITDHDDFVINKLT 102

 Score = 38.1 bits (87), Expect = 0.018,   Method: Compositional matrix adjust.
 Identities = 25/109 (22%), Positives = 45/109 (41%), Gaps = 4/109 (3%)
 Frame = -1

Query: 385 NAGMYQCIAENAYGSIYANAELKI----LALAPTFEMNPMKKKILAAKGGRVIIECKPKA 440
           +AG+Y C       S Y     KI    + + P+ +       +   +G    + C    
Sbjct: 646 DAGIYTCTVRITAVS-YEEWPTKIGNLTVQVPPSIKPGDTTAVLQIEQGQNSTLVCAASG 470

Query: 441 APKPKFSWSKGTEWLVNSSRILIWEDGSLEINNITRNDGGIYTCFAENN 489
            P P  +W++     +    +  +   +L +NN+T  D G+Y C A+NN
Sbjct: 469 IPAPNITWTRSDGGFLPIG-VAQFRSATLPMNNVTVRDMGVYRCVADNN 326

 Score = 34.7 bits (78), Expect = 0.18,   Method: Compositional matrix adjust.
 Identities = 32/125 (25%), Positives = 52/125 (41%), Gaps = 6/125 (4%)
 Frame = -1

Query: 469 LEINNITRNDGGIYTCF----AENNRGKANSTGTLVITNPTRIILAPINADITV--GENA 522
           L +  +   D GIYTC     A +        G L +  P  I      A + +  G+N+
Sbjct: 673 LVVRRLVETDAGIYTCTVRITAVSYEEWPTKIGNLTVQVPPSIKPGDTTAVLQIEQGQNS 494

Query: 523 TMQCAASFDPALDLTFVWSFNGYVIDFNKEITHIHYQRNFMLDANGELLIRNAQLKHAGR 582
           T+ CAAS  PA ++T+  S  G++      I    ++       +  L + N  ++  G 
Sbjct: 493 TLVCAASGIPAPNITWTRSDGGFL-----PIGVAQFR-------SATLPMNNVTVRDMGV 350

Query: 583 YTCTA 587
           Y C A
Sbjct: 349 YRCVA 335
>17229
          Length = 487

 Score = 46.6 bits (109), Expect = 6e-05,   Method: Compositional matrix adjust.
 Identities = 36/135 (26%), Positives = 61/135 (45%), Gaps = 12/135 (8%)
 Frame = +1

Query: 869 RLENLLPDTQYFIEVGACNSAGCGPSSDVIETFTRKAPPSQPPRIISSVRSGSRYIITWD 928
           RL +L PDT Y+I+V A    G GP +  I+T T    P +P ++ +   + +   + WD
Sbjct: 61  RLHDLTPDTIYYIQVSAKTVHGEGPRTPTIQTKTLPFLPGEPRKLRAETINSTGIFVEWD 240

Query: 929 HVVALSNESTVTGYKILY-RPDGQHD----GKLFSTH-------KHSIEVPIPRDGEYVV 976
                 +   + GY + Y + +G  D    G     H       K ++ + +  D  Y V
Sbjct: 241 E--PKDSRGKIRGYYVYYVKVNGSRDEPPSGLTEQVHDTVSGRVKEAVIIGLDADSRYRV 414

Query: 977 EVRAHSDGGDGVVSQ 991
           +V  ++  GDG  S+
Sbjct: 415 QVAGYTRKGDGRRSK 459
>11788
          Length = 569

 Score = 45.1 bits (105), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 47/167 (28%), Positives = 65/167 (38%), Gaps = 18/167 (10%)
 Frame = +1

Query: 839 VESYQIRYW----AGHDKEAAAHR-----VQVTSQEYSARLENLLPDTQYFIEVGACNSA 889
           V  YQI +W    +G + +    R     ++    E    +  L  +  Y++ V   N+A
Sbjct: 7   VLGYQINWWHWGASGENCDGFQDREIIRFIRHYGPEKQGAVIGLFANDDYWVTVQVFNTA 186

Query: 890 GCGPSSDVIETFTRKAPPSQPPRIISSVRSGSRYI-ITWDHVVALSNESTVTGYKILYRP 948
           G    S      T    P   P  +     G   + + W  V  +  ES V+GYKI Y P
Sbjct: 187 GLSRPSGCNYMNTNYEAPLHYPEYVQVSSHGPESVQVFWRGVSTIQIESPVSGYKIWYWP 366

Query: 949 --DGQHDGKL------FSTHKHSIEVPIPRDGEYVVEVRAHSDGGDG 987
             D     K+      FS   H IE    RD  Y + V   SDGGDG
Sbjct: 367 YTDNIRTAKVAVFPKVFSGVLHGIE----RDKIYKLRVLGTSDGGDG 495

 Score = 39.3 bits (90), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 35/131 (26%), Positives = 52/131 (39%), Gaps = 4/131 (3%)
 Frame = +1

Query: 782 FQVKVKAFNNKGDGPYSLVAVINSAQDAPSEAPTEVGVKVLSSSEISVHWKHV----LEK 837
           + V V+ FN  G    S    +N+  +AP   P  V V       + V W+ V    +E 
Sbjct: 154 YWVTVQVFNTAGLSRPSGCNYMNTNYEAPLHYPEYVQVSSHGPESVQVFWRGVSTIQIES 333

Query: 838 IVESYQIRYWAGHDKEAAAHRVQVTSQEYSARLENLLPDTQYFIEVGACNSAGCGPSSDV 897
            V  Y+I YW   D    A +V V  + +S  L  +  D  Y + V   +  G G     
Sbjct: 334 PVSGYKIWYWPYTDNIRTA-KVAVFPKVFSGVLHGIERDKIYKLRVLGTSDGGDG----- 495

Query: 898 IETFTRKAPPS 908
                +K PP+
Sbjct: 496 -----KKTPPT 513
>38127
          Length = 860

 Score = 44.7 bits (104), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 39/140 (27%), Positives = 55/140 (39%), Gaps = 14/140 (10%)
 Frame = -1

Query: 185 KRRFVSQTNGNLYIANVESSDRGNYSCFVS-SPSITKSVFSKFIPLIPIPERTTKPYPAD 243
           K R++   NG L I +   +  G Y+C      +  KS  S  +P    P    K  P D
Sbjct: 830 KERYIQHNNGTLEIQHPRRNFAGMYTCVAEYEEAGVKSSISVDVPFYAHP----KVLPFD 663

Query: 244 IVVQFKDIYTMMGQNVTLECFALGNPVPDIRW-------------RKVLEPMPSTAEIST 290
                K    +  +++ +EC  LG P P + W             R  L+P  S    S 
Sbjct: 662 -----KSKNLVQDESLVIECKVLGYPKPVVSWYMDNVEIVDGADSRYSLKPANSYDGASI 498

Query: 291 SGAVLKIFNIQLEDEGLYEC 310
            GA L I  +Q +D G Y C
Sbjct: 497 EGAKLVIEEVQFDDAGEYTC 438

 Score = 40.0 bits (92), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 37/157 (23%), Positives = 56/157 (35%), Gaps = 12/157 (7%)
 Frame = -1

Query: 386 AGMYQCIAENAYGSIYANAELKILALAPTFEMNPMKKKILAAKGGRVIIECKPKAAPKPK 445
           AGMY C+AE     + ++  + +   A   ++ P  K     +   ++IECK    PKP 
Sbjct: 767 AGMYTCVAEYEEAGVKSSISVDVPFYAHP-KVLPFDKSKNLVQDESLVIECKVLGYPKPV 591

Query: 446 FSWSKGTEWLV------------NSSRILIWEDGSLEINNITRNDGGIYTCFAENNRGKA 493
            SW      +V            NS      E   L I  +  +D G YTC +       
Sbjct: 590 VSWYMDNVEIVDGADSRYSLKPANSYDGASIEGAKLVIEEVQFDDAGEYTCMSNYTDKWP 411

Query: 494 NSTGTLVITNPTRIILAPINADITVGENATMQCAASF 530
               T VI    +    P    + +     + CA  F
Sbjct: 410 QFNSTQVILVRVKTSWRPCGPFLGIVAEVVVLCAIIF 300

 Score = 35.0 bits (79), Expect = 0.15,   Method: Compositional matrix adjust.
 Identities = 33/139 (23%), Positives = 56/139 (40%), Gaps = 11/139 (7%)
 Frame = -1

Query: 460 RILIWEDGSLEINNITRNDGGIYTCFAENNRGKANSTGTLVITNPTRIILAPIN--ADIT 517
           R +   +G+LEI +  RN  G+YTC AE       S+ ++ +       + P +   ++ 
Sbjct: 824 RYIQHNNGTLEIQHPRRNFAGMYTCVAEYEEAGVKSSISVDVPFYAHPKVLPFDKSKNLV 645

Query: 518 VGENATMQCAASFDPALDLTFVWSFNGYVIDFNKEITHIHYQRNFMLDAN---------G 568
             E+  ++C     P   ++  W  +      N EI      R  +  AN          
Sbjct: 644 QDESLVIECKVLGYPKPVVS--WYMD------NVEIVDGADSRYSLKPANSYDGASIEGA 489

Query: 569 ELLIRNAQLKHAGRYTCTA 587
           +L+I   Q   AG YTC +
Sbjct: 488 KLVIEEVQFDDAGEYTCMS 432
>11855
          Length = 1574

 Score = 44.3 bits (103), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 43/185 (23%), Positives = 69/185 (37%), Gaps = 49/185 (26%)
 Frame = +1

Query: 356 GKPIPTIRWLKNG-------------------------------YSYHKGELRLYDVTFE 384
           G P+PTI WLK+G                                S  K  L L   T +
Sbjct: 1   GSPVPTIHWLKDGVRLTQSTYETVDDESALYEDLASDPGQPRLRLSSTKSRLYLDCPTSQ 180

Query: 385 NAGMYQCIAENAYGSIYANAELKILALAPTFEMNPMKKKILAAKGGRVI----------- 433
           + G Y C+AE  +     +  +K+     + ++  M K+    +  RV            
Sbjct: 181 DEGEYTCVAETPFKRRVQSTIVKVDTRHYSPDVTCMSKRGSRGEPARVYMWTVSRLELET 360

Query: 434 ----IECKPKAAPKPKFSWSKGTEWLV--NSSRILIWEDGSLEINNITRNDG-GIYTCFA 486
               + C+    P+P  +W  G    +  NS +  I  +G L I +I+ ++  G+Y C A
Sbjct: 361 TTVQLFCRASGYPEPTITWYDGRNNSLPDNSGQFSIAVNGDLIIRDISWSENMGVYRCVA 540

Query: 487 ENNRG 491
           EN  G
Sbjct: 541 ENELG 555

 Score = 43.1 bits (100), Expect = 6e-04,   Method: Compositional matrix adjust.
 Identities = 43/160 (26%), Positives = 65/160 (40%), Gaps = 13/160 (8%)
 Frame = +1

Query: 186 RRFVSQTNGNLYIANVESSDRGNYSCFVSSP-------SITKSVFSKFIP-LIPIPERTT 237
           R  +S T   LY+    S D G Y+C   +P       +I K     + P +  + +R +
Sbjct: 124 RLRLSSTKSRLYLDCPTSQDEGEYTCVAETPFKRRVQSTIVKVDTRHYSPDVTCMSKRGS 303

Query: 238 KPYPADIVVQFKDIYTMMGQNVTLECFALGNPVPDIRW----RKVLEPMPSTAEISTSGA 293
           +  PA + +       +    V L C A G P P I W       L        I+ +G 
Sbjct: 304 RGEPARVYMWTVSRLELETTTVQLFCRASGYPEPTITWYDGRNNSLPDNSGQFSIAVNGD 483

Query: 294 VLKIFNIQL-EDEGLYECEAENIRGKDKHQARIYVQAFPE 332
           ++ I +I   E+ G+Y C AEN  G    QA +Y     E
Sbjct: 484 LI-IRDISWSENMGVYRCVAENELGSHSVQAFLYPTTLDE 600

 Score = 37.7 bits (86), Expect = 0.024,   Method: Compositional matrix adjust.
 Identities = 48/201 (23%), Positives = 71/201 (35%), Gaps = 61/201 (30%)
 Frame = +1

Query: 267 GNPVPDIRWRK-----------------------VLEPMPSTAEISTSGAVLKIFNIQLE 303
           G+PVP I W K                         +P      +S++ + L +     +
Sbjct: 1   GSPVPTIHWLKDGVRLTQSTYETVDDESALYEDLASDPGQPRLRLSSTKSRLYLDCPTSQ 180

Query: 304 DEGLYECEAE--------------------------NIRGKDKHQARIYVQAFPEWVEHI 337
           DEG Y C AE                          + RG     AR+Y+         +
Sbjct: 181 DEGEYTCVAETPFKRRVQSTIVKVDTRHYSPDVTCMSKRGSRGEPARVYMWTVSRL--EL 354

Query: 338 NDTEVDIGSDLYWPCIATGKPIPTIRWLK--------NGYSYH---KGELRLYDVTF-EN 385
             T V +       C A+G P PTI W          N   +     G+L + D+++ EN
Sbjct: 355 ETTTVQLF------CRASGYPEPTITWYDGRNNSLPDNSGQFSIAVNGDLIIRDISWSEN 516

Query: 386 AGMYQCIAENAYGSIYANAEL 406
            G+Y+C+AEN  GS    A L
Sbjct: 517 MGVYRCVAENELGSHSVQAFL 579

 Score = 36.6 bits (83), Expect = 0.053,   Method: Compositional matrix adjust.
 Identities = 22/63 (34%), Positives = 29/63 (46%), Gaps = 2/63 (3%)
 Frame = +1

Query: 61  VSLNCRARASPFPVYKWR--MNNGDVDLTNDRYSMVGGNLVINNPDKQKDAGVYYCLASN 118
           V L CRA   P P   W    NN   D +      V G+L+I +    ++ GVY C+A N
Sbjct: 367 VQLFCRASGYPEPTITWYDGRNNSLPDNSGQFSIAVNGDLIIRDISWSENMGVYRCVAEN 546

Query: 119 NYG 121
             G
Sbjct: 547 ELG 555
>06028
          Length = 1358

 Score = 43.9 bits (102), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 59/278 (21%), Positives = 110/278 (39%), Gaps = 44/278 (15%)
 Frame = +1

Query: 273 IRWRKVLEPMPS-----TAEISTSGAVLKIFNIQLEDEGLYECEAEN------------I 315
           I+W K  EP+ +       + +   + L I N   +D G+Y C A N             
Sbjct: 4   IQWMKGTEPISNDEKYQQVDQADGYSKLIIHNPVEKDSGVYFCVASNEGAQNKISHQVDF 183

Query: 316 RGKDKHQARIYVQAF------PEWVEHINDTEVDIGSDLYWPC--IATGKPIPTIRWLKN 367
           +G+++         F      P ++  + +  V  G  +      + +  PI  ++WL+N
Sbjct: 184 KGRERFTLEKTAGFFHRDPNKPHFLNPLGNQTVCHGGTVAISAEFMQSSTPI-EVKWLRN 360

Query: 368 -----GYSYHK-GELRLYDVTFENAG-----MYQCIAENAYGSIYANAELKILA-----L 411
                G S     E  +Y +   NAG      Y C+A NA+G I ++  + +       +
Sbjct: 361 RRPVDGPSVQTFNERGIYTLAIMNAGEEHEGTYTCLASNAFGRIESHVNIDVAVGVEKEV 540

Query: 412 APTFEMNPMKKKILAAKGGRVIIECKPKAAPKPKFSWSKGTEWLVNSSRIL--IWEDGS- 468
            P   ++  + ++  A G    +  +    PKP+  + KGT+ +  S R+   + +D + 
Sbjct: 541 RPPLFLSRPETEMKIAVGDPFSLSFRIAGDPKPRLVFMKGTKDITQSDRVSKEVSDDYTR 720

Query: 469 LEINNITRNDGGIYTCFAENNRGKANSTGTLVITNPTR 506
             +     +D G Y   A N+ G      T+ I  P +
Sbjct: 721 FTVQKSQISDSGTYFVVARNDFGTDRIFVTITIKTPKK 834

 Score = 35.0 bits (79), Expect = 0.14,   Method: Compositional matrix adjust.
 Identities = 60/258 (23%), Positives = 94/258 (36%), Gaps = 28/258 (10%)
 Frame = +1

Query: 98  LVINNPDKQKDAGVYYCLASNN------------YGMVRST-EATLSFGYLDXXXXXXXX 144
           L+I+NP  +KD+GVY+C+ASN              G  R T E T  F + D        
Sbjct: 85  LIIHNP-VEKDSGVYFCVASNEGAQNKISHQVDFKGRERFTLEKTAGFFHRDPNKPHFLN 261

Query: 145 --XXXXXXGKGMVLLCDPPYHFPDDLSYRWLLNEFPV----FITMDKRRFVSQTNGNLYI 198
                     G V +          +  +WL N  PV      T ++R   +     L I
Sbjct: 262 PLGNQTVCHGGTVAISAEFMQSSTPIEVKWLRNRRPVDGPSVQTFNERGIYT-----LAI 426

Query: 199 ANVESSDRGNYSCFVSSPSITKSVFSKFIPLIPIP-----ERTTKPYPADIVVQFKDIYT 253
            N      G Y+C  S      + F +    + I      E+  +P P  +     ++  
Sbjct: 427 MNAGEEHEGTYTCLAS------NAFGRIESHVNIDVAVGVEKEVRP-PLFLSRPETEMKI 585

Query: 254 MMGQNVTLECFALGNPVPDIRWRK----VLEPMPSTAEISTSGAVLKIFNIQLEDEGLYE 309
            +G   +L     G+P P + + K    + +    + E+S       +   Q+ D G Y 
Sbjct: 586 AVGDPFSLSFRIAGDPKPRLVFMKGTKDITQSDRVSKEVSDDYTRFTVQKSQISDSGTYF 765

Query: 310 CEAENIRGKDKHQARIYV 327
             A N  G D    RI+V
Sbjct: 766 VVARNDFGTD----RIFV 807
>17679
          Length = 509

 Score = 40.0 bits (92), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 29/112 (25%), Positives = 50/112 (44%), Gaps = 3/112 (2%)
 Frame = +3

Query: 802 VINSAQDAPSEAPTEVGVKVLSSSEISVHWK--HVLEKIVESYQIRYWAGHDKEAAA-HR 858
           ++    +AP  AP  V  +  SS+ I V W    +   I++ Y++ Y    ++      +
Sbjct: 102 IVQVLVEAPGTAPRNVRARAASSTTIVVSWSEPEIPNGIIQGYRVFYTRKPEEPVFFWEQ 281

Query: 859 VQVTSQEYSARLENLLPDTQYFIEVGACNSAGCGPSSDVIETFTRKAPPSQP 910
            +V +      +  L P+  Y I + A +S G GP S  I+  T +  P QP
Sbjct: 282 QEVKNDNRLTTISGLDPNQTYTISILAYSSIGPGPMSHPIQVLTTQGVPYQP 437
>18345
          Length = 461

 Score = 38.9 bits (89), Expect = 0.010,   Method: Composition-based stats.
 Identities = 19/61 (31%), Positives = 30/61 (49%), Gaps = 2/61 (3%)
 Frame = +1

Query: 256 GQNVTLECFALGNPVPDIRW--RKVLEPMPSTAEISTSGAVLKIFNIQLEDEGLYECEAE 313
           G   TL C   G P PD+ W  R   +       + ++G VL ++N+    + +YEC A+
Sbjct: 157 GDTATLVCNVTGVPSPDVTWYKRNTRQLDAQKERVGSTGPVLVMYNVTRHCDDIYECYAD 336

Query: 314 N 314
           N
Sbjct: 337 N 339

 Score = 32.7 bits (73), Expect = 0.80,   Method: Composition-based stats.
 Identities = 24/114 (21%), Positives = 46/114 (40%), Gaps = 1/114 (0%)
 Frame = +1

Query: 376 LRLYDVTFENAGMYQCIAENAYGSIYANAELKILALAPTFEMNPMKKKILAAKGGRVIIE 435
           L +  V   + G+Y+C        I     +  +      E +P   ++   +G    + 
Sbjct: 4   LLIRHVRLNDTGVYECRINTQPSQIKQVTLVVQVPPVVLSEGSP--DRVSLKEGDTATLV 177

Query: 436 CKPKAAPKPKFSWSKGTEWLVNSSRILIWEDGS-LEINNITRNDGGIYTCFAEN 488
           C     P P  +W K     +++ +  +   G  L + N+TR+   IY C+A+N
Sbjct: 178 CNVTGVPSPDVTWYKRNTRQLDAQKERVGSTGPVLVMYNVTRHCDDIYECYADN 339
>34369
          Length = 300

 Score = 36.6 bits (83), Expect = 0.060,   Method: Compositional matrix adjust.
 Identities = 22/89 (24%), Positives = 45/89 (50%), Gaps = 1/89 (1%)
 Frame = +3

Query: 614 IEDIRATSVALTWSRG-SDNHSPISKYTIQTKTILSDDWKDAKTDPPIIEGNMESAKAVD 672
           ++ I +  V + W+    DN+SPI+ YT+Q    +++   D      +  G+       +
Sbjct: 6   VDFIESREVTVYWTTSRDDNNSPITSYTVQ----VNECENDTTVRELVTGGSTFQITIPN 173

Query: 673 LIPWMEYEFRVVATNTLGTGEPSIPSNRI 701
           L P+  Y  +V+A N++G  +P   S+++
Sbjct: 174 LTPYTCYAIQVLAQNSVGFSDPGPQSDQV 260
>36498
          Length = 478

 Score = 33.1 bits (74), Expect = 0.63,   Method: Composition-based stats.
 Identities = 13/38 (34%), Positives = 20/38 (52%)
 Frame = +1

Query: 241 PADIVVQFKDIYTMMGQNVTLECFALGNPVPDIRWRKV 278
           P   V     I  ++G  V +EC A G+P P + WR++
Sbjct: 52  PTVTVTPGTRITALVGDRVDIECVAEGDPTPTVFWRRI 165

 Score = 31.6 bits (70), Expect = 1.9,   Method: Composition-based stats.
 Identities = 20/56 (35%), Positives = 26/56 (46%)
 Frame = +1

Query: 395 NAYGSIYANAELKILALAPTFEMNPMKKKILAAKGGRVIIECKPKAAPKPKFSWSK 450
           NA G++   A L I    PT  + P   +I A  G RV IEC  +  P P   W +
Sbjct: 1   NAAGTVTLTASLVIQG-PPTVTVTP-GTRITALVGDRVDIECVAEGDPTPTVFWRR 162
>20244
          Length = 452

 Score = 30.0 bits (66), Expect(2) = 0.65,   Method: Composition-based stats.
 Identities = 13/39 (33%), Positives = 23/39 (58%)
 Frame = -3

Query: 184 DKRRFVSQTNGNLYIANVESSDRGNYSCFVSSPSITKSV 222
           ++ R+V  +NG+L I  V  +D G Y C+ ++ S  + V
Sbjct: 312 NQGRYVLTSNGDLTIVQVRQTDDGTYVCWPATVSANQCV 196

 Score = 21.6 bits (44), Expect(2) = 0.65,   Method: Compositional matrix adjust.
 Identities = 6/20 (30%), Positives = 9/20 (45%)
 Frame = -2

Query: 256 GQNVTLECFALGNPVPDIRW 275
           G  +   C   G P P++ W
Sbjct: 121 GSTIAFNCSVQGYPTPNVTW 62

 Score = 29.6 bits (65), Expect(3) = 0.77,   Method: Composition-based stats.
 Identities = 11/20 (55%), Positives = 12/20 (60%)
 Frame = -1

Query: 256 GQNVTLECFALGNPVPDIRW 275
           G    L CFA GNP P+I W
Sbjct: 398 GGIAVLRCFATGNPAPNITW 339

 Score = 20.4 bits (41), Expect(3) = 0.77,   Method: Compositional matrix adjust.
 Identities = 7/20 (35%), Positives = 10/20 (50%)
 Frame = -2

Query: 345 GSDLYWPCIATGKPIPTIRW 364
           GS + + C   G P P + W
Sbjct: 121 GSTIAFNCSVQGYPTPNVTW 62

 Score = 19.2 bits (38), Expect(3) = 0.77,   Method: Composition-based stats.
 Identities = 8/23 (34%), Positives = 12/23 (52%)
 Frame = -3

Query: 288 ISTSGAVLKIFNIQLEDEGLYEC 310
           + TS   L I  ++  D+G Y C
Sbjct: 297 VLTSNGDLTIVQVRQTDDGTYVC 229
>03196
          Length = 1743

 Score = 32.0 bits (71), Expect = 1.3,   Method: Composition-based stats.
 Identities = 14/38 (36%), Positives = 22/38 (57%)
 Frame = +3

Query: 191  QTNGNLYIANVESSDRGNYSCFVSSPSITKSVFSKFIP 228
            +  GN Y+A  E++ RG   C +   ++ +SVFS F P
Sbjct: 1389 EREGNAYLAVHETATRGCRGCQLRQANVNQSVFSLFAP 1502
>05835
          Length = 2803

 Score = 25.4 bits (54), Expect(2) = 1.8,   Method: Compositional matrix adjust.
 Identities = 14/33 (42%), Positives = 17/33 (51%)
 Frame = -3

Query: 295  LKIFNIQLEDEGLYECEAENIRGKDKHQARIYV 327
            L+I  ++   EG Y C A N    DK  ARI V
Sbjct: 1991 LQIEGLEKHHEGDYTCVAFNQHHTDKATARIKV 1893

 Score = 24.6 bits (52), Expect(2) = 1.8,   Method: Compositional matrix adjust.
 Identities = 17/51 (33%), Positives = 24/51 (47%)
 Frame = -1

Query: 242  ADIVVQFKDIYTMMGQNVTLECFALGNPVPDIRWRKVLEPMPSTAEISTSG 292
            A IV   + +      NV L+C A+G P P   W   L P+P+T   +  G
Sbjct: 2197 ARIVTMPEYVRNHTHTNVVLQCEAIGLPTPP--WPGCL-PVPTTRPSTCQG 2054
>22019
          Length = 314

 Score = 31.2 bits (69), Expect = 2.5,   Method: Composition-based stats.
 Identities = 15/47 (31%), Positives = 28/47 (59%)
 Frame = +3

Query: 457 NSSRILIWEDGSLEINNITRNDGGIYTCFAENNRGKANSTGTLVITN 503
           +SSR  + E  +L + ++T  D G+Y C   N  G+A++   L++T+
Sbjct: 9   HSSRNSVGEVHTLLLQDVTNEDAGLYVCELSNMVGQASAVLQLLVTD 149
>32888
          Length = 418

 Score = 30.8 bits (68), Expect = 2.7,   Method: Compositional matrix adjust.
 Identities = 14/36 (38%), Positives = 19/36 (52%)
 Frame = -3

Query: 343 DIGSDLYWPCIATGKPIPTIRWLKNGYSYHKGELRL 378
           D G  +   C A GKP P + W KNG+    G+ R+
Sbjct: 239 DEGQTVRLDCRAKGKPSPKVTWYKNGHIITNGDDRV 132

 Score = 28.1 bits (61), Expect(2) = 4.9,   Method: Compositional matrix adjust.
 Identities = 11/22 (50%), Positives = 13/22 (59%)
 Frame = -3

Query: 256 GQNVTLECFALGNPVPDIRWRK 277
           GQ V L+C A G P P + W K
Sbjct: 233 GQTVRLDCRAKGKPSPKVTWYK 168

 Score = 20.4 bits (41), Expect(2) = 4.9,   Method: Compositional matrix adjust.
 Identities = 9/24 (37%), Positives = 13/24 (54%)
 Frame = -2

Query: 295 LKIFNIQLEDEGLYECEAENIRGK 318
           L I ++  ED+G Y C   N  G+
Sbjct: 114 LTIKSLGAEDKGNYTCIVSNTEGQ 43
>04905
          Length = 1868

 Score = 30.8 bits (68), Expect = 3.1,   Method: Compositional matrix adjust.
 Identities = 11/43 (25%), Positives = 22/43 (51%)
 Frame = +2

Query: 423  KILAAKGGRVIIECKPKAAPKPKFSWSKGTEWLVNSSRILIWE 465
            K++  +  +VI+ C     P+   SWS     L +  ++L+W+
Sbjct: 1211 KMMITRKVKVIVPCPELHPPRSHLSWSHKNHHLFDLQKLLLWQ 1339
>11767
          Length = 690

 Score = 30.0 bits (66), Expect = 4.8,   Method: Composition-based stats.
 Identities = 13/27 (48%), Positives = 17/27 (62%)
 Frame = +1

Query: 433 IIECKPKAAPKPKFSWSKGTEWLVNSS 459
           +I+CKP   PKP  + S+GTE L   S
Sbjct: 544 LIDCKPPPLPKPAVTESQGTEKLSEES 624
>29932
          Length = 748

 Score = 30.0 bits (66), Expect = 5.1,   Method: Compositional matrix adjust.
 Identities = 31/125 (24%), Positives = 51/125 (40%), Gaps = 12/125 (9%)
 Frame = +3

Query: 303 EDEGLYECEAENIRGKDKHQA--RIYVQAFPEWVEHIN---DTEVDIGSDLYWPCIATGK 357
           ++ G Y C A + RG         + +   P+     N   + E D   ++Y  C  T  
Sbjct: 3   QNLGQYRCNAIDPRGSIVTFVVRELVLLPLPQITFRPNIPLEVEADRNIEIY--CDVTNA 176

Query: 358 PIPTIRWLKN------GYSYHKGE-LRLYDVTFENAGMYQCIAENAYGSIYANAELKILA 410
               ++W  +      G  +  G+ LR   +T  +AG Y C A N YG+    A+  ++ 
Sbjct: 177 RPENVQWATDNNRPLPGSVHIDGQILRFVAITPADAGGYSCTASNKYGTNSKTAQ--VVV 350

Query: 411 LAPTF 415
             PTF
Sbjct: 351 RPPTF 365
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|124378024|ref|NP_766447.2| hypothetical protein
LOC241688 [Mus musculus]
         (778 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

28691                                                                  73   4e-13
12417                                                                  37   0.040
28494                                                                  35   0.14 
00540                                                                  33   0.49 
08473                                                                  32   0.89 
05924                                                                  32   1.0  
11861                                                                  32   1.4  
10586                                                                  31   1.8  
08299                                                                  31   2.1  
22708                                                                  30   3.0  
06253                                                                  30   5.5  
13458                                                                  29   6.8  
04308                                                                  29   7.3  
29919                                                                  29   8.4  
>28691
          Length = 562

 Score = 73.2 bits (178), Expect = 4e-13,   Method: Compositional matrix adjust.
 Identities = 44/109 (40%), Positives = 61/109 (55%), Gaps = 3/109 (2%)
 Frame = +1

Query: 667 GRPAVIVAVVNKHYEAIPVLAQRGADIDQQWGPFR---NTALHEATLLGLEGRESIATLL 723
           G PA+ +A  NKH + IPVL Q GAD++ + GP     NTALHEA  +G    +S+  LL
Sbjct: 118 GLPALHLAAKNKHVDCIPVLVQAGADVNAK-GPSTIKGNTALHEAVSVGASNVDSVDALL 294

Query: 724 GCNANAQKKNTRGQTAYDIALEMGDDLTSSLFAAKFTQGLEDQLSPPGN 772
            C A+    N +G+TAYD+A + G +     FAA   Q    ++  P N
Sbjct: 295 SCGADQNIXNEKGETAYDLASKAGYENIVKRFAAAMGQSQLQKMIRPRN 441
>12417
          Length = 954

 Score = 36.6 bits (83), Expect = 0.040,   Method: Compositional matrix adjust.
 Identities = 27/88 (30%), Positives = 40/88 (45%), Gaps = 6/88 (6%)
 Frame = +2

Query: 633 KLLLEEVGS------SGKGRLSVLEQLLDEGADPNCCDSQGRPAVIVAVVNKHYEAIPVL 686
           K  LEE  S      + +G   +  QL+  GAD N     GR  +  A    H   + +L
Sbjct: 212 KAWLEERASVALAMAANRGLDKMCSQLIQTGADVNSATEHGRTPLHXASAQGHGHIVDLL 391

Query: 687 AQRGADIDQQWGPFRNTALHEATLLGLE 714
            ++GADID +   + +TAL  A   G +
Sbjct: 392 LEKGADIDAE-DDYGDTALSIADQFGFK 472
>28494
          Length = 463

 Score = 34.7 bits (78), Expect = 0.14,   Method: Compositional matrix adjust.
 Identities = 25/104 (24%), Positives = 47/104 (45%), Gaps = 6/104 (5%)
 Frame = -1

Query: 607 PESIKKMKNLKAKSFLVNPEPLTPENKLLLEEV--GSSGKGRLSVLEQLLDEGADPNCCD 664
           P  +K+ ++ +    L  P P   + K     V   +   G    +++LL+ GAD N  +
Sbjct: 406 PTGLKRWEDSETNRELGYPRPSAKKVKFQDGCVFLAACSSGDRDEVKKLLERGADINTAN 227

Query: 665 SQGRPAVIVAVVNKHYEAIPVLAQRGADID----QQWGPFRNTA 704
             G  A+  A ++ + + +  L ++ AD+D    + W P   TA
Sbjct: 226 VDGLTALHQACIDDNLDMVEFLVEQNADVDVCDNEGWTPLHATA 95
>00540
          Length = 3034

 Score = 33.1 bits (74), Expect = 0.49,   Method: Compositional matrix adjust.
 Identities = 22/67 (32%), Positives = 34/67 (50%), Gaps = 6/67 (8%)
 Frame = -2

Query: 618  AKSFLVNPEPLTPENKLLLEEVGSSGKGR------LSVLEQLLDEGADPNCCDSQGRPAV 671
             K+ + +P+  +P +   +E + S G+ R      LSV   L+  GAD N  DSQG  A+
Sbjct: 1872 VKTGITDPDGASPLHLACMENISSFGRVRMSHFPSLSVTRILIKVGADTNARDSQGNVAL 1693

Query: 672  IVAVVNK 678
              A + K
Sbjct: 1692 HFASMGK 1672
>08473
          Length = 942

 Score = 32.0 bits (71), Expect = 0.89,   Method: Compositional matrix adjust.
 Identities = 16/49 (32%), Positives = 29/49 (59%)
 Frame = -1

Query: 644 KGRLSVLEQLLDEGADPNCCDSQGRPAVIVAVVNKHYEAIPVLAQRGAD 692
           +G +S+ + L+D+GA+ N  D      ++VA    + EA+  L +RGA+
Sbjct: 789 RGEISICKLLVDKGANVNAADKMLITPLMVAAREGNREAVEFLLKRGAN 643
>05924
          Length = 704

 Score = 32.0 bits (71), Expect = 1.0,   Method: Composition-based stats.
 Identities = 21/69 (30%), Positives = 36/69 (52%), Gaps = 1/69 (1%)
 Frame = +1

Query: 680 YEAIPVLAQRGADIDQQ-WGPFRNTALHEATLLGLEGRESIATLLGCNANAQKKNTRGQT 738
           ++A+  L + G D++ + W  + +T LHEA  +  E  + +  L+   ANA   N  G+T
Sbjct: 4   HKAVQRLVKGGVDVNARFW--YDSTLLHEAVSMASE--DLVQMLIKAGANANSTNQDGRT 171

Query: 739 AYDIALEMG 747
           A  +A   G
Sbjct: 172 ALHLACRGG 198
>11861
          Length = 586

 Score = 31.6 bits (70), Expect = 1.4,   Method: Composition-based stats.
 Identities = 26/98 (26%), Positives = 45/98 (45%), Gaps = 1/98 (1%)
 Frame = -1

Query: 650 LEQLLDEGADPNCCDSQGRPAVIVAVVNKHYEAIPVLAQRGADIDQQWGPFRNTALHEAT 709
           +++LL  GAD +  +S  +P V +AV  K ++ +  L    ADI   + P +      +T
Sbjct: 331 VKELLIRGADASATESSRKPLVKLAVRKKQWDVVKALILNHADI---YRPDKMGQTPLST 161

Query: 710 LLGLEGRESIA-TLLGCNANAQKKNTRGQTAYDIALEM 746
           L+     E I   +  C   A   +  GQT   +A ++
Sbjct: 160 LITAANMEMIHFAIQHCPGMAGAVDMSGQTILHVACQL 47
>10586
          Length = 1036

 Score = 31.2 bits (69), Expect = 1.8,   Method: Compositional matrix adjust.
 Identities = 11/26 (42%), Positives = 16/26 (61%)
 Frame = +1

Query: 327 TCEGPLPPTQEQWLCNGDEVPHPPAR 352
           T +G +  +  QWLCN D+  H PA+
Sbjct: 457 TFDGAISISALQWLCNADKKSHKPAK 534
>08299
          Length = 917

 Score = 30.8 bits (68), Expect = 2.1,   Method: Compositional matrix adjust.
 Identities = 11/28 (39%), Positives = 18/28 (64%)
 Frame = +2

Query: 336 QEQWLCNGDEVPHPPARNGETISCSRCG 363
           Q++W+    E   PPAR  E+++CS+ G
Sbjct: 146 QQEWMSLTFEPSLPPARGSESVACSKTG 229
>22708
          Length = 337

 Score = 30.4 bits (67), Expect = 3.0,   Method: Compositional matrix adjust.
 Identities = 11/28 (39%), Positives = 19/28 (67%)
 Frame = -1

Query: 336 QEQWLCNGDEVPHPPARNGETISCSRCG 363
           Q++W+    E+  PPAR  E+++CS+ G
Sbjct: 163 QQEWMSLIFELSLPPARGSESVACSKTG 80
>06253
          Length = 1049

 Score = 29.6 bits (65), Expect = 5.5,   Method: Compositional matrix adjust.
 Identities = 27/103 (26%), Positives = 45/103 (43%)
 Frame = -1

Query: 641 SSGKGRLSVLEQLLDEGADPNCCDSQGRPAVIVAVVNKHYEAIPVLAQRGADIDQQWGPF 700
           ++G  R  +++ LL  GAD +  D  G   +  A    H+E   +L   GA ++     +
Sbjct: 566 AAGYNRTRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHFEVTEMLLXAGASVN-AVDLW 390

Query: 701 RNTALHEATLLGLEGRESIATLLGCNANAQKKNTRGQTAYDIA 743
           + T LHEA        E  + LL   A+    N   ++  D+A
Sbjct: 389 QFTPLHEAA--SKSRVEVCSLLLAHGADPNLVNCHSKSIIDVA 267
>13458
          Length = 404

 Score = 29.3 bits (64), Expect = 6.8,   Method: Composition-based stats.
 Identities = 10/18 (55%), Positives = 15/18 (83%)
 Frame = -2

Query: 36 SDTPDVNIYYTLDGSKPD 53
          S+T D  IYYT++G++PD
Sbjct: 61 SETKDAKIYYTINGTRPD 8
>04308
          Length = 1078

 Score = 28.9 bits (63), Expect = 7.3,   Method: Compositional matrix adjust.
 Identities = 10/28 (35%), Positives = 18/28 (64%)
 Frame = -2

Query: 336  QEQWLCNGDEVPHPPARNGETISCSRCG 363
            Q++W+    E+  PP R  E+++CS+ G
Sbjct: 1011 QQEWMSLTFELSLPPXRGSESVACSKTG 928
>29919
          Length = 1247

 Score = 28.9 bits (63), Expect = 8.4,   Method: Compositional matrix adjust.
 Identities = 19/73 (26%), Positives = 32/73 (43%), Gaps = 7/73 (9%)
 Frame = -2

Query: 338 QWLC-------NGDEVPHPPARNGETISCSRCGCQNLWEASFCDWCGAMLGISASHSVCP 390
           +WLC       +  ++  P  +    +S  RC  + +  + F D    +LG+S  H + P
Sbjct: 742 RWLCEATVSWVHAWKIFFPLLKRMTRLSAGRCKVRGVTISVFPD--HRLLGLSMIHLLLP 569

Query: 391 KCGASNHLTARFC 403
            C     + ARFC
Sbjct: 568 TCSIVFFVCARFC 530
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|112799851|ref|NP_775554.2| tumor protein p53 binding
protein, 2 [Mus musculus]
         (1134 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

28494                                                                  73   6e-13
09180                                                                  57   4e-08
05924                                                                  55   1e-07
06253                                                                  55   2e-07
15772                                                                  54   3e-07
25470                                                                  54   5e-07
19166                                                                  50   4e-06
13462                                                                  47   4e-05
08473                                                                  47   5e-05
02114                                                                  46   7e-05
15359                                                                  43   7e-04
09292                                                                  42   0.002
30463                                                                  41   0.002
11295                                                                  40   0.005
27108                                                                  40   0.006
20884                                                                  40   0.007
38834                                                                  39   0.008
28113                                                                  38   0.019
07940                                                                  36   0.11 
36917                                                                  35   0.12 
08755                                                                  35   0.13 
00540                                                                  35   0.14 
35952                                                                  35   0.14 
14005                                                                  35   0.16 
25464                                                                  35   0.16 
20036                                                                  35   0.20 
02351                                                                  35   0.21 
16561                                                                  35   0.22 
27067                                                                  34   0.29 
36879                                                                  34   0.42 
21532                                                                  32   1.0  
09214                                                                  32   1.3  
20121                                                                  32   1.4  
22305                                                                  32   1.5  
18216                                                                  32   2.1  
28691                                                                  31   2.3  
30978                                                                  30   3.8  
11888                                                                  30   4.0  
33484                                                                  30   6.1  
02689                                                                  30   7.0  
11861                                                                  29   8.3  
10881                                                                  29   8.8  
03590                                                                  29   8.9  
>28494
          Length = 463

 Score = 73.2 bits (178), Expect = 6e-13,   Method: Composition-based stats.
 Identities = 34/96 (35%), Positives = 60/96 (62%)
 Frame = -1

Query: 927  RVKFNPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQ 986
            +VKF    + L +   G+ D V++++    D +  N +G+TALH A    + ++V+FLV+
Sbjct: 334  KVKFQDGCVFLAACSSGDRDEVKKLLERGADINTANVDGLTALHQACIDDNLDMVEFLVE 155

Query: 987  FGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGA 1022
               +V+  D++GWTPLH  ASC   ++ ++L+E+GA
Sbjct: 154  QNADVDVCDNEGWTPLHATASCGFTEIARYLLENGA 47
>09180
          Length = 610

 Score = 57.0 bits (136), Expect = 4e-08,   Method: Compositional matrix adjust.
 Identities = 27/78 (34%), Positives = 40/78 (51%), Gaps = 10/78 (12%)
 Frame = +3

Query: 965  GITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVE----- 1019
            G TALH +   G+  ++  L+Q GV++NA D+DGWT LH A        C+ LV+     
Sbjct: 165  GATALHVSAAKGYINVMNVLLQAGVDINAQDADGWTSLHAAVHWGQEDSCQVLVDHFCDM 344

Query: 1020 -----SGAAVFAMTYSDM 1032
                 +G  VF +   +M
Sbjct: 345  DVKNNAGHTVFDLADKEM 398
>05924
          Length = 704

 Score = 55.5 bits (132), Expect = 1e-07,   Method: Composition-based stats.
 Identities = 34/82 (41%), Positives = 45/82 (54%)
 Frame = +1

Query: 943  GEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPL 1002
            G  ++VQ +I    D +    +G T LH AV  GHTE+V  LV  G +VN  DS G +PL
Sbjct: 196  GYTNIVQILIAAGTDVNRRTVDGKTCLHVAVWRGHTEVVVKLVNAGADVNIPDSVGCSPL 375

Query: 1003 HCAASCNNVQVCKFLVESGAAV 1024
            + AA  N   +   LV +GA V
Sbjct: 376  YWAARSNYTAILTVLVNAGAKV 441

 Score = 51.2 bits (121), Expect = 2e-06,   Method: Composition-based stats.
 Identities = 32/79 (40%), Positives = 43/79 (54%)
 Frame = +1

Query: 946  DLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCA 1005
            DLVQ +I    + +  N +G TALH A   G+T IV+ L+  G +VN    DG T LH A
Sbjct: 106  DLVQMLIKAGANANSTNQDGRTALHLACRGGYTNIVQILIAAGTDVNRRTVDGKTCLHVA 285

Query: 1006 ASCNNVQVCKFLVESGAAV 1024
                + +V   LV +GA V
Sbjct: 286  VWRGHTEVVVKLVNAGADV 342

 Score = 45.4 bits (106), Expect = 1e-04,   Method: Composition-based stats.
 Identities = 24/80 (30%), Positives = 42/80 (52%)
 Frame = +1

Query: 943  GEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPL 1002
            G  ++V +++    D ++P+  G + L+ A  + +T I+  LV  G  VN      WTPL
Sbjct: 295  GHTEVVVKLVNAGADVNIPDSVGCSPLYWAARSNYTAILTVLVNAGAKVNYRVKSKWTPL 474

Query: 1003 HCAASCNNVQVCKFLVESGA 1022
            H A    ++ V ++L+  GA
Sbjct: 475  HAALHLGHMGVVRYLLLQGA 534
>06253
          Length = 1049

 Score = 55.1 bits (131), Expect = 2e-07,   Method: Composition-based stats.
 Identities = 30/76 (39%), Positives = 43/76 (56%)
 Frame = -1

Query: 947  LVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAA 1006
            +VQ ++    D    +  G+  LHNA   GH E+ + L+  G +VNA D   +TPLH AA
Sbjct: 542  IVQLLLQHGADVHAKDKGGLVPLHNACSYGHFEVTEMLLXAGASVNAVDLWQFTPLHEAA 363

Query: 1007 SCNNVQVCKFLVESGA 1022
            S + V+VC  L+  GA
Sbjct: 362  SKSRVEVCSLLLAHGA 315

 Score = 52.8 bits (125), Expect = 7e-07,   Method: Composition-based stats.
 Identities = 28/80 (35%), Positives = 45/80 (56%)
 Frame = -1

Query: 943  GEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPL 1002
            G  D+V+ ++    +    +D G+  LHNA   GH E+V+ L++ G + NA D+  +TPL
Sbjct: 1013 GRKDVVEHLLENGANVHARDDGGLIPLHNACSFGHAEVVQLLLRHGADPNARDNWNYTPL 834

Query: 1003 HCAASCNNVQVCKFLVESGA 1022
            H AA    + VC  L++  A
Sbjct: 833  HEAAIKGKIDVCIVLLQQCA 774

 Score = 45.1 bits (105), Expect = 2e-04,   Method: Composition-based stats.
 Identities = 37/165 (22%), Positives = 71/165 (43%), Gaps = 21/165 (12%)
 Frame = -1

Query: 936  LLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALH------NAVCAG------------- 976
            L +++++G+ D+   ++ +  DP++ N +G TAL        AV  G             
Sbjct: 836  LHEAAIKGKIDVCIVLLQQCADPNIRNTDGKTALDLADASAKAVLTGEYKKDELLEAARS 657

Query: 977  --HTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAVFAMTYSDMQT 1034
                +++  L    VN +A+D    TPLH AA  N  ++ + L++ GA V A     +  
Sbjct: 656  GNEEQMMALLTPLNVNCHASDGRKSTPLHLAAGYNRTRIVQLLLQHGADVHAKDKGGLVP 477

Query: 1035 AADKCEEMEEGYTQCSQFLYGVQEKMGIMNKGVIYALWDYEPQHD 1079
              + C     G+ + ++ L      +  ++      LW + P H+
Sbjct: 476  LHNAC---SYGHFEVTEMLLXAGASVNAVD------LWQFTPLHE 369

 Score = 30.4 bits (67), Expect = 4.6,   Method: Composition-based stats.
 Identities = 18/63 (28%), Positives = 31/63 (49%)
 Frame = -1

Query: 943  GEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPL 1002
            G  ++VQ ++    DP+  ++   T LH A   G  ++   L+Q   + N  ++DG T L
Sbjct: 914  GHAEVVQLLLRHGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQQCADPNIRNTDGKTAL 735

Query: 1003 HCA 1005
              A
Sbjct: 734  DLA 726
>15772
          Length = 1282

 Score = 54.3 bits (129), Expect = 3e-07,   Method: Composition-based stats.
 Identities = 39/124 (31%), Positives = 58/124 (46%), Gaps = 6/124 (4%)
 Frame = -3

Query: 936  LLDSSLEGEFD----LVQRIIYEVD--DPSLPNDEGITALHNAVCAGHTEIVKFLVQFGV 989
            L D++  G++D     V+  IY+V+  DP   N    TALH A   G  E ++ L+  G 
Sbjct: 1274 LHDAASTGDYDALEDYVKSGIYDVNLKDPDAGNK---TALHWACQKGFVECIRLLLDHGA 1104

Query: 990  NVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAVFAMTYSDMQTAADKCEEMEEGYTQC 1049
               A    GWTP HCAA CN V   + L    AA+  +  +D      +      G+  C
Sbjct: 1103 KGTARTDTGWTPAHCAAECNRVTALRAL---HAALVPVDLTDKYGDTPRRIATLYGHRDC 933

Query: 1050 SQFL 1053
            +++L
Sbjct: 932  ARYL 921
>25470
          Length = 400

 Score = 53.5 bits (127), Expect = 5e-07,   Method: Composition-based stats.
 Identities = 28/80 (35%), Positives = 45/80 (56%)
 Frame = -3

Query: 943  GEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPL 1002
            G  D+V+ ++    +    +D G+  LHNA   GH E+V+ L++ G + NA D+  +TPL
Sbjct: 365  GRKDVVEHLLENGANVHARDDGGLIPLHNACSFGHAEVVQLLLRHGADPNARDNWNYTPL 186

Query: 1003 HCAASCNNVQVCKFLVESGA 1022
            H AA    + VC  L++  A
Sbjct: 185  HEAAIKGKIDVCIVLLQQCA 126

 Score = 30.4 bits (67), Expect = 3.7,   Method: Composition-based stats.
 Identities = 18/63 (28%), Positives = 31/63 (49%)
 Frame = -3

Query: 943  GEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPL 1002
            G  ++VQ ++    DP+  ++   T LH A   G  ++   L+Q   + N  ++DG T L
Sbjct: 266  GHAEVVQLLLRHGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQQCADPNIRNTDGKTAL 87

Query: 1003 HCA 1005
              A
Sbjct: 86   DLA 78
>19166
          Length = 447

 Score = 50.4 bits (119), Expect = 4e-06,   Method: Composition-based stats.
 Identities = 31/90 (34%), Positives = 46/90 (51%)
 Frame = +1

Query: 939  SSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDG 998
            SS  G  ++V  +I     P  P   G T+LH A  A  T+I++ L++ G  V+A   + 
Sbjct: 178  SSFMGHMNIVIYLIQHNAYPDTPTVRGETSLHLAARANQTDIIRILLRNGAAVDARAREQ 357

Query: 999  WTPLHCAASCNNVQVCKFLVESGAAVFAMT 1028
             TPLH A+   NV     L++ GA+  A T
Sbjct: 358  QTPLHIASRLGNVDNVVLLLQHGASADATT 447

 Score = 42.4 bits (98), Expect = 0.001,   Method: Composition-based stats.
 Identities = 23/64 (35%), Positives = 33/64 (51%)
 Frame = +1

Query: 963  DEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGA 1022
            + G+T LH +   GH  IV +L+Q     +     G T LH AA  N   + + L+ +GA
Sbjct: 151  ESGLTPLHVSSFMGHMNIVIYLIQHNAYPDTPTVRGETSLHLAARANQTDIIRILLRNGA 330

Query: 1023 AVFA 1026
            AV A
Sbjct: 331  AVDA 342
>13462
          Length = 1388

 Score = 47.0 bits (110), Expect = 4e-05,   Method: Composition-based stats.
 Identities = 24/80 (30%), Positives = 46/80 (57%)
 Frame = +3

Query: 943  GEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPL 1002
            G   +V  ++     P++ +++G TALH A    + ++V+ L+++G +V  AD D  TPL
Sbjct: 216  GNLGIVSMLLAYGAQPNVQDEDGNTALHLACSESNVDVVRLLLEWGGDVAVADIDNETPL 395

Query: 1003 HCAASCNNVQVCKFLVESGA 1022
              A   N+V++   L+ +G+
Sbjct: 396  VRACLANSVELVDLLLHAGS 455
>08473
          Length = 942

 Score = 47.0 bits (110), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 29/71 (40%), Positives = 38/71 (53%), Gaps = 1/71 (1%)
 Frame = -1

Query: 957  DPSLPNDEGITALHNAVCAG-HTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCK 1015
            D  + +   +TALH+A CAG H   V  L+Q G N    +  G TPL  AA    + +CK
Sbjct: 942  DVDMRDSNDMTALHHA-CAGLHYGCVHALLQGGANPTCMEMGGKTPLFYAAHRGEISICK 766

Query: 1016 FLVESGAAVFA 1026
             LV+ GA V A
Sbjct: 765  LLVDKGANVNA 733

 Score = 42.4 bits (98), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 28/79 (35%), Positives = 37/79 (46%)
 Frame = -1

Query: 944  EFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLH 1003
             +  V  ++    +P+     G T L  A   G   I K LV  G NVNAAD    TPL 
Sbjct: 882  HYGCVHALLQGGANPTCMEMGGKTPLFYAAHRGEISICKLLVDKGANVNAADKMLITPLM 703

Query: 1004 CAASCNNVQVCKFLVESGA 1022
             AA   N +  +FL++ GA
Sbjct: 702  VAAREGNREAVEFLLKRGA 646
>02114
          Length = 1072

 Score = 46.2 bits (108), Expect = 7e-05,   Method: Composition-based stats.
 Identities = 29/97 (29%), Positives = 48/97 (49%), Gaps = 2/97 (2%)
 Frame = +1

Query: 959  SLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLV 1018
            S  +  G T LH A   GH+  V+ L++ GV+VN+ D   WT +H ++    +   + L+
Sbjct: 283  SAKDTRGSTPLHLACAHGHSFCVQTLLRCGVDVNSVDKTSWTSVHVSSYHGRLGCLQMLI 462

Query: 1019 ESGAAVFAMTYSDMQTAADKCEEME--EGYTQCSQFL 1053
            + GA      Y D+ T  +    +   EG+  C +FL
Sbjct: 463  KWGA-----RYDDIDTNGNTPAHLAAMEGHLPCLKFL 558

 Score = 37.0 bits (84), Expect = 0.045,   Method: Composition-based stats.
 Identities = 26/84 (30%), Positives = 42/84 (50%), Gaps = 1/84 (1%)
 Frame = +1

Query: 942  EGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGV-NVNAADSDGWT 1000
            E   + +  + +E+D P    +    A H A   G  + ++ LV+ GV N+N  D  G T
Sbjct: 649  ENILEYIDHVQHEMDHPEQAENLAFPA-HMAAYNGELDHLRILVENGVVNINERDDKGNT 825

Query: 1001 PLHCAASCNNVQVCKFLVESGAAV 1024
              H AA   ++ + ++LVE GA V
Sbjct: 826  LAHRAAGQGHLNILQWLVEMGADV 897

 Score = 32.7 bits (73), Expect = 0.75,   Method: Composition-based stats.
 Identities = 17/54 (31%), Positives = 30/54 (55%)
 Frame = +1

Query: 967  TALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVES 1020
            T++H +   G    ++ L+++G   +  D++G TP H AA   ++   KFLV S
Sbjct: 406  TSVHVSSYHGRLGCLQMLIKWGARYDDIDTNGNTPAHLAAMEGHLPCLKFLVSS 567

 Score = 31.6 bits (70), Expect = 2.1,   Method: Composition-based stats.
 Identities = 24/81 (29%), Positives = 41/81 (50%), Gaps = 2/81 (2%)
 Frame = +1

Query: 939  SSLEGEFDLVQRIIYE--VDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADS 996
            ++  GE D + RI+ E  V + +  +D+G T  H A   GH  I+++LV+ G +V  ++ 
Sbjct: 736  AAYNGELDHL-RILVENGVVNINERDDKGNTLAHRAAGQGHLNILQWLVEMGADVEISNG 912

Query: 997  DGWTPLHCAASCNNVQVCKFL 1017
             G T    A    ++   K L
Sbjct: 913  AGETARDIARRFAHLACVKLL 975
>15359
          Length = 780

 Score = 43.1 bits (100), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 23/55 (41%), Positives = 30/55 (54%), Gaps = 1/55 (1%)
 Frame = +1

Query: 965  GITALHNAVCAGHTEIVKFLV-QFGVNVNAADSDGWTPLHCAASCNNVQVCKFLV 1018
            G TALH A   G  E+VK L  + GV +N     G+TPLH AA   +  + + LV
Sbjct: 349  GYTALHWAAKFGKPEVVKMLANKIGVEINQRSHGGYTPLHLAAIHGHEDIIELLV 513
>09292
          Length = 1486

 Score = 41.6 bits (96), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 25/80 (31%), Positives = 40/80 (50%)
 Frame = -2

Query: 943  GEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPL 1002
            G   +   ++    D +  N+   T LH     GH  +V+ LV+ G + NA D D  TP+
Sbjct: 1329 GSVKMASVLLKHXADVNARNNVDRTPLHIXAIEGHLGLVEELVRHGADFNAEDKDHLTPV 1150

Query: 1003 HCAASCNNVQVCKFLVESGA 1022
              A   N+  + ++L+ESGA
Sbjct: 1149 FNACVKNDTDIVRYLLESGA 1090

 Score = 41.6 bits (96), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 39/143 (27%), Positives = 64/143 (44%), Gaps = 13/143 (9%)
 Frame = -2

Query: 906  LPPGKRTNLRKTGSERIAHGMRVKFNPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEG 965
            L  G R N   T +  I H ++  ++ +  LL             +++     SLP  + 
Sbjct: 1104 LESGARAN---TTARPIFHAVKYGYSEIVQLL-------------LVHGAAVNSLPGTK- 976

Query: 966  ITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASC-NNVQVCKFLVESGAAV 1024
             + LH A   G+ E+ + ++  G NVNA D DG TPLH +    ++ Q+ + L+  GA V
Sbjct: 975  -SPLHIACRNGNIEMARTVIIAGANVNAVDKDGNTPLHISVRAPSSAQLVRLLIRFGANV 799

Query: 1025 ------------FAMTYSDMQTA 1035
                         A  YS+++TA
Sbjct: 798  KWGNDNQQIPLHLACLYSNLETA 730

 Score = 41.2 bits (95), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 25/82 (30%), Positives = 41/82 (50%)
 Frame = -2

Query: 941  LEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWT 1000
            + G  D+V+ ++    D + P+      LH A       I + L++ G NVN +  +G T
Sbjct: 654  IGGNVDIVRLVLQGSSDVNSPDGRNNAPLHLACMKQCIGIARCLLRHGANVNVSGYNGRT 475

Query: 1001 PLHCAASCNNVQVCKFLVESGA 1022
            PLH A S +N+++   L   GA
Sbjct: 474  PLHIAISHHNLELVLLLYMCGA 409

 Score = 37.0 bits (84), Expect = 0.041,   Method: Compositional matrix adjust.
 Identities = 21/83 (25%), Positives = 43/83 (51%), Gaps = 1/83 (1%)
 Frame = -2

Query: 942  EGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCA-GHTEIVKFLVQFGVNVNAADSDGWT 1000
             G  ++ + +I    + +  + +G T LH +V A    ++V+ L++FG NV   + +   
Sbjct: 951  NGNIEMARTVIIAGANVNAVDKDGNTPLHISVRAPSSAQLVRLLIRFGANVKWGNDNQQI 772

Query: 1001 PLHCAASCNNVQVCKFLVESGAA 1023
            PLH A   +N++  + L+  G+ 
Sbjct: 771  PLHLACLYSNLETARLLLHCGSC 703
>30463
          Length = 412

 Score = 41.2 bits (95), Expect = 0.002,   Method: Composition-based stats.
 Identities = 23/68 (33%), Positives = 35/68 (51%)
 Frame = -1

Query: 959  SLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLV 1018
            +L    G TA H A   GH+  V  L   G +++    D  TPLH A+S  +++  K LV
Sbjct: 406  TLETPTGYTATHLAAMNGHSNAVMVLNIMGASIDCRTVDKQTPLHLASSAGHIECVKCLV 227

Query: 1019 ESGAAVFA 1026
             + A++ A
Sbjct: 226  ANKASLTA 203
>11295
          Length = 1179

 Score = 40.0 bits (92), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 20/58 (34%), Positives = 32/58 (55%)
 Frame = +1

Query: 962  NDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVE 1019
            +++ +TALH A C    E+   L+++G    A D  G TPLH A  C +  V + L++
Sbjct: 166  SNDHVTALHIACCLDDREMASLLLKYGAYAMALDVIGHTPLHVACWCGSEGVTRLLLD 339

 Score = 38.5 bits (88), Expect = 0.014,   Method: Compositional matrix adjust.
 Identities = 18/49 (36%), Positives = 29/49 (59%)
 Frame = +1

Query: 943 GEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNV 991
           G   ++Q ++    +P++ +DEGIT L+ A C GH  IV  L+Q G  +
Sbjct: 706 GHLTMLQLLLQGKAEPNVVDDEGITPLYIASCEGHVTIVNILLQSGAKI 852

 Score = 35.4 bits (80), Expect = 0.14,   Method: Compositional matrix adjust.
 Identities = 21/70 (30%), Positives = 38/70 (54%), Gaps = 4/70 (5%)
 Frame = +1

Query: 962  NDEGITALHNAVCAGHTEIVKFLVQF----GVNVNAADSDGWTPLHCAASCNNVQVCKFL 1017
            +  G++ALH+A    +TE+ + L+      G+ VNA  +D  T LH A   ++ ++   L
Sbjct: 55   DHRGLSALHHACIGRNTEVAELLLDGWNGDGIAVNATSNDHVTALHIACCLDDREMASLL 234

Query: 1018 VESGAAVFAM 1027
            ++ GA   A+
Sbjct: 235  LKYGAYAMAL 264

 Score = 33.1 bits (74), Expect = 0.62,   Method: Compositional matrix adjust.
 Identities = 16/50 (32%), Positives = 29/50 (58%)
 Frame = +1

Query: 976  GHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAVF 1025
            GH  +++ L+Q     N  D +G TPL+ A+   +V +   L++SGA ++
Sbjct: 706  GHLTMLQLLLQGKAEPNVVDDEGITPLYIASCEGHVTIVNILLQSGAKIY 855

 Score = 32.3 bits (72), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 12/25 (48%), Positives = 18/25 (72%)
 Frame = +1

Query: 979  EIVKFLVQFGVNVNAADSDGWTPLH 1003
            E++  L++FG +VN AD   +TPLH
Sbjct: 616  EMLSLLIKFGASVNCADHYHYTPLH 690
>27108
          Length = 449

 Score = 39.7 bits (91), Expect = 0.006,   Method: Composition-based stats.
 Identities = 17/32 (53%), Positives = 22/32 (68%)
 Frame = -3

Query: 957 DPSLPNDEGITALHNAVCAGHTEIVKFLVQFG 988
           D  L N EGITALH+AV   H  +VK L+++G
Sbjct: 150 DMHLANQEGITALHDAVSMNHVSVVKLLLKYG 55

 Score = 37.4 bits (85), Expect = 0.034,   Method: Composition-based stats.
 Identities = 25/79 (31%), Positives = 37/79 (46%), Gaps = 20/79 (25%)
 Frame = -3

Query: 965  GITALHNAVCAGHTEIVKFLVQF--------------------GVNVNAADSDGWTPLHC 1004
            G TALH A   GH E  + L++F                     V+++ A+ +G T LH 
Sbjct: 285  GWTALHEACNHGHLECARALLKFVPSATLDSFFQSGKNRGKVRKVDMHLANQEGITALHD 106

Query: 1005 AASCNNVQVCKFLVESGAA 1023
            A S N+V V K L++ G +
Sbjct: 105  AVSMNHVSVVKLLLKYGGS 49
>20884
          Length = 712

 Score = 39.7 bits (91), Expect = 0.007,   Method: Composition-based stats.
 Identities = 23/62 (37%), Positives = 32/62 (51%), Gaps = 1/62 (1%)
 Frame = +2

Query: 957  DPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAAD-SDGWTPLHCAASCNNVQVCK 1015
            D ++ N EG T  H A+  GH  I+  L++ G N+N  D   G T LH AA    +Q  +
Sbjct: 527  DLAIRNYEGYTCAHLALQTGHLHILPLLLERGANINEQDGKSGRTLLHMAADLGYLQALE 706

Query: 1016 FL 1017
             L
Sbjct: 707  LL 712
>38834
          Length = 496

 Score = 39.3 bits (90), Expect = 0.008,   Method: Composition-based stats.
 Identities = 23/77 (29%), Positives = 38/77 (49%)
 Frame = -1

Query: 962  NDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESG 1021
            N  G T  H +V     +I  FLV+    +N  ++ G TP++ AA   N ++   +V +G
Sbjct: 424  NINGYTPXHLSVYFNKFDITHFLVKINAEINTVNNAGQTPVYLAALRGNSKILALMVNAG 245

Query: 1022 AAVFAMTYSDMQTAADK 1038
              V  +  SD+ T  +K
Sbjct: 244  CKVNGLV-SDISTRINK 197

 Score = 38.9 bits (89), Expect = 0.011,   Method: Composition-based stats.
 Identities = 17/53 (32%), Positives = 29/53 (54%)
 Frame = -1

Query: 972  AVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAV 1024
            A  +GH +I + L + GV +N  + +G+TP H +   N   +  FLV+  A +
Sbjct: 493  ACSSGHLDIAEMLHRRGVQINVVNINGYTPXHLSVYFNKFDITHFLVKINAEI 335
>28113
          Length = 449

 Score = 38.1 bits (87), Expect = 0.019,   Method: Composition-based stats.
 Identities = 28/101 (27%), Positives = 47/101 (46%)
 Frame = -3

Query: 939  SSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDG 998
            S+ +G+   VQ ++      S  +     A+H A   G  ++V+ L+  G + N  +S+ 
Sbjct: 312  SAAQGDVHHVQSLLNHGHHHSKKDSIAWAAIHYASWYGSADVVEILLDAGCSPNLTNSEL 133

Query: 999  WTPLHCAASCNNVQVCKFLVESGAAVFAMTYSDMQTAADKC 1039
             TPLH AA      V + LV++ A    +   D + A D C
Sbjct: 132  LTPLHIAAKKGFPDVAEHLVQAEAIDLNLRDKDGKRAIDIC 10
>07940
          Length = 1336

 Score = 35.8 bits (81), Expect = 0.11,   Method: Compositional matrix adjust.
 Identities = 26/90 (28%), Positives = 44/90 (48%), Gaps = 2/90 (2%)
 Frame = -3

Query: 623 APGKNFQQAVQSALTKTQPRGPHFSSV--YGKPVIAAAQNPQQHPENIYSCSQGKPGSPE 680
           AP  N +  ++S     +P G  +S +  Y +PVI ++ +   HP +  S +QG      
Sbjct: 584 APHGNLRDFLKSH----RPHGTSYSCIADYEQPVITSSSSSFSHPNSASSSAQGTSLGFI 417

Query: 681 PETETVSSVHESHENERIPRPLSPTKLLPF 710
           P T TVS    SH  + + + L+P  L+ +
Sbjct: 416 PGTSTVSFSTGSHRQDML-KMLTPKDLISY 330
>36917
          Length = 443

 Score = 35.4 bits (80), Expect = 0.12,   Method: Composition-based stats.
 Identities = 15/37 (40%), Positives = 22/37 (59%)
 Frame = -1

Query: 969  LHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCA 1005
            LH A   G+ E+ +FL+   V+V+  D + W PLH A
Sbjct: 113  LHIAAANGYIEVAEFLLDNHVSVDRQDHESWQPLHAA 3
>08755
          Length = 885

 Score = 35.4 bits (80), Expect = 0.13,   Method: Composition-based stats.
 Identities = 21/64 (32%), Positives = 35/64 (54%), Gaps = 1/64 (1%)
 Frame = +3

Query: 962  NDEGITALHNAVCAGHTEIVKFLVQFGVNVNA-ADSDGWTPLHCAASCNNVQVCKFLVES 1020
            +D+G +ALH AV   + E++  L+  G N +   D  G TPL  AAS       + L+ +
Sbjct: 645  SDDGQSALHIAV--KNPEVISVLLAHGANPDVKVDGSGVTPLMLAASMTKTAALQILIGA 818

Query: 1021 GAAV 1024
            G+++
Sbjct: 819  GSSI 830
>00540
          Length = 3034

 Score = 35.4 bits (80), Expect = 0.14,   Method: Composition-based stats.
 Identities = 21/58 (36%), Positives = 31/58 (53%)
 Frame = -2

Query: 967  TALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAV 1024
            T L  A   GH E+V+FLV+    +  A+S G T L  A    ++ V ++L+  GA V
Sbjct: 2964 TPLRAACYDGHLEVVQFLVEHKAEIEIANSHGHTCLMIACYRGHLDVVEYLLYLGAQV 2791
>35952
          Length = 1624

 Score = 35.4 bits (80), Expect = 0.14,   Method: Compositional matrix adjust.
 Identities = 22/59 (37%), Positives = 31/59 (52%), Gaps = 1/59 (1%)
 Frame = -1

Query: 965  GITALHNAVCAGHTEIVKFLV-QFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGA 1022
            G TALH+AV      +  FL+ +   +VNA   DG TPLH A     + +   L+ +GA
Sbjct: 973  GRTALHHAVELDDLPVAGFLLMEANADVNARCFDGNTPLHVACCRGLIGMVALLMTAGA 797
>14005
          Length = 1745

 Score = 35.0 bits (79), Expect = 0.16,   Method: Compositional matrix adjust.
 Identities = 19/56 (33%), Positives = 30/56 (53%), Gaps = 1/56 (1%)
 Frame = -1

Query: 968  ALHNAVCAGHTEIVKFLVQFGVNVNAADSD-GWTPLHCAASCNNVQVCKFLVESGA 1022
            AL+ A      E+VK LV++G  VNA  ++  WTP H      + ++  +L+  GA
Sbjct: 1634 ALYFACMGNDIELVKQLVRYGARVNAYSTETWWTPFHACCKRGDPRIALYLLRHGA 1467

 Score = 34.3 bits (77), Expect = 0.32,   Method: Compositional matrix adjust.
 Identities = 21/67 (31%), Positives = 32/67 (47%), Gaps = 4/67 (5%)
 Frame = -1

Query: 949  QRIIYEVD----DPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHC 1004
            Q +IY +D    + +    +G  ALH A    H ++V+ L+  G N    +  GWTP + 
Sbjct: 1199 QHVIYLLDFCDAEVNAATLKGNNALHIACRGKHADLVELLLHKGANPAQRNQRGWTPRNS 1020

Query: 1005 AASCNNV 1011
            A  C  V
Sbjct: 1019 AGRCXEV 999

 Score = 31.2 bits (69), Expect = 2.8,   Method: Compositional matrix adjust.
 Identities = 23/90 (25%), Positives = 40/90 (44%), Gaps = 1/90 (1%)
 Frame = -1

Query: 936  LLDSSLEGEFDLVQRII-YEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAA 994
            L  + +  + +LV++++ Y     +   +   T  H     G   I  +L++ G N  + 
Sbjct: 1631 LYFACMGNDIELVKQLVRYGARVNAYSTETWWTPFHACCKRGDPRIALYLLRHGANKESR 1452

Query: 995  DSDGWTPLHCAASCNNVQVCKFLVESGAAV 1024
              DG TPL  A   +  +V   L+ SGA V
Sbjct: 1451 TVDGKTPLVVACKNDKAEVALLLIRSGANV 1362
>25464
          Length = 440

 Score = 35.0 bits (79), Expect = 0.16,   Method: Compositional matrix adjust.
 Identities = 21/57 (36%), Positives = 33/57 (57%), Gaps = 1/57 (1%)
 Frame = -3

Query: 965  GITALHNAVCAGHTEIVKFLVQFGV-NVNAADSDGWTPLHCAASCNNVQVCKFLVES 1020
            G TAL  A   G  +IV+ +++  V ++N  D+DG TP+H AA   N  + + L E+
Sbjct: 411  GRTALSYACLNGRQDIVRCILKEDVLDINEPDNDGNTPIHHAAISANPNIVRMLAEA 241
>20036
          Length = 1849

 Score = 34.7 bits (78), Expect = 0.20,   Method: Compositional matrix adjust.
 Identities = 20/73 (27%), Positives = 36/73 (49%)
 Frame = +3

Query: 946  DLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCA 1005
            D+++++    D  +     G TAL  A     T++V+ L++ G + N  D DG T L CA
Sbjct: 1044 DIIRQLFLAGDINACAEQTGQTALMLATSQCRTDMVELLLETGADCNQQDFDGSTALMCA 1223

Query: 1006 ASCNNVQVCKFLV 1018
                +  + + L+
Sbjct: 1224 CEHGHTAIVQLLL 1262
>02351
          Length = 939

 Score = 34.7 bits (78), Expect = 0.21,   Method: Composition-based stats.
 Identities = 22/68 (32%), Positives = 33/68 (48%), Gaps = 2/68 (2%)
 Frame = +3

Query: 956  DDPSLP--NDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQV 1013
            DD + P   D+G TALH A   G+   V+ L+ +  NV   D +G   L  A +  +V+ 
Sbjct: 435  DDINSPYGKDDGRTALHIAAALGNVVYVQLLLWYCANVKVVDHEGRNALWYARTSGSVEC 614

Query: 1014 CKFLVESG 1021
               L  +G
Sbjct: 615  TDLLAAAG 638
>16561
          Length = 2029

 Score = 34.7 bits (78), Expect = 0.22,   Method: Composition-based stats.
 Identities = 16/61 (26%), Positives = 32/61 (52%)
 Frame = -3

Query: 964  EGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAA 1023
            +G TALH +      ++++ L+  G  +NA ++ G + LH A +  +++    L+  G  
Sbjct: 2015 DGDTALHYSAFGNQPDVLQLLLSKGAKINALNNGGCSTLHVAVNKQHIKCVHVLLNXGCD 1836

Query: 1024 V 1024
            V
Sbjct: 1835 V 1833
>27067
          Length = 409

 Score = 34.3 bits (77), Expect = 0.29,   Method: Composition-based stats.
 Identities = 21/59 (35%), Positives = 30/59 (50%), Gaps = 8/59 (13%)
 Frame = +1

Query: 962  NDEGITALHNAV--CAGHTEI------VKFLVQFGVNVNAADSDGWTPLHCAASCNNVQ 1012
            N  G TA+H+ +  C G  EI      +  + + G N+NA D  G +PLH A S  N +
Sbjct: 217  NIRGKTAMHHCLLSCGGFVEIEDMVTCMDLVYKAGGNINAQDWFGTSPLHLAISTENFE 393

 Score = 33.5 bits (75), Expect = 0.55,   Method: Composition-based stats.
 Identities = 17/59 (28%), Positives = 35/59 (59%), Gaps = 1/59 (1%)
 Frame = +1

Query: 964  EGITALHNAVCAGHTEIVKFLVQF-GVNVNAADSDGWTPLHCAASCNNVQVCKFLVESG 1021
            +G +A+H A+   +T+I+++L+   G+  NA ++   TP+  AAS   ++    L++ G
Sbjct: 22   KGSSAVHEAIKVNNTDILRYLLTVPGLECNAVNASQKTPVMEAASRGRIECLTMLLDHG 198
>36879
          Length = 583

 Score = 33.9 bits (76), Expect = 0.42,   Method: Composition-based stats.
 Identities = 17/40 (42%), Positives = 24/40 (60%)
 Frame = -3

Query: 988  GVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAVFAM 1027
            G+N++A D  G TPL  AA      VC+ L+E+GA   A+
Sbjct: 494  GINIHAIDDVGETPLMLAAKNGQDYVCERLLEAGADPLAI 375
>21532
          Length = 460

 Score = 32.3 bits (72), Expect = 1.0,   Method: Compositional matrix adjust.
 Identities = 23/87 (26%), Positives = 41/87 (47%), Gaps = 7/87 (8%)
 Frame = -1

Query: 947  LVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVN-------VNAADSDGW 999
            ++  ++    D ++ ++ G T   NA C G+   VK L+  G +       +N  D+   
Sbjct: 451  IINTLLSHGADVNIRDNTGCTPFANACCLGNLAAVKALLTPGESPSWSKPMINVRDNSQN 272

Query: 1000 TPLHCAASCNNVQVCKFLVESGAAVFA 1026
            TPLH A+   +  + + LVE  A + A
Sbjct: 271  TPLHLASQEGHTAIVELLVEHKADLAA 191
>09214
          Length = 2116

 Score = 32.0 bits (71), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 14/34 (41%), Positives = 20/34 (58%)
 Frame = -3

Query: 965  GITALHNAVCAGHTEIVKFLVQFGVNVNAADSDG 998
            G TALH      H  +V++L+  G + NA D+DG
Sbjct: 1610 GRTALHWGAKRDHQTVVQYLLSHGADKNAVDNDG 1509
>20121
          Length = 454

 Score = 32.0 bits (71), Expect = 1.4,   Method: Composition-based stats.
 Identities = 17/66 (25%), Positives = 31/66 (46%)
 Frame = -1

Query: 954  EVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQV 1013
            E  DP      G TALH +V  GH E  + L++ G      ++  W+ LH      + ++
Sbjct: 268  ETKDP-----RGRTALHLSVSLGHLESTRVLLRHGAEAGTENNGCWSVLHEGVCSGDPEL 104

Query: 1014 CKFLVE 1019
             + +++
Sbjct: 103  VQLILQ 86
>22305
          Length = 426

 Score = 32.0 bits (71), Expect = 1.5,   Method: Composition-based stats.
 Identities = 16/51 (31%), Positives = 26/51 (50%)
 Frame = -3

Query: 962  NDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQ 1012
            N  GI  LH A+C  + E+ + L+Q+G + N        PL  AA   +++
Sbjct: 295  NHWGILPLHEALCWENVEVGRVLLQYGADPNVPCETNVVPLTFAARTGHIR 143
>18216
          Length = 472

 Score = 31.6 bits (70), Expect = 2.1,   Method: Composition-based stats.
 Identities = 16/35 (45%), Positives = 22/35 (62%)
 Frame = +2

Query: 988  GVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGA 1022
            GV+VNA D  GWT    AA   ++ V + L+E+GA
Sbjct: 275  GVHVNAVDPFGWTAAMSAAFEGHLAVVQTLLEAGA 379
>28691
          Length = 562

 Score = 31.2 bits (69), Expect = 2.3,   Method: Composition-based stats.
 Identities = 25/69 (36%), Positives = 34/69 (49%), Gaps = 5/69 (7%)
 Frame = +1

Query: 959  SLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNA---ADSDGWTPLHCAAS--CNNVQV 1013
            S+ +  G+ ALH A    H + +  LVQ G +VNA   +   G T LH A S   +NV  
Sbjct: 100  SVESKSGLPALHLAAKNKHVDCIPVLVQAGADVNAKGPSTIKGNTALHEAVSVGASNVDS 279

Query: 1014 CKFLVESGA 1022
               L+  GA
Sbjct: 280  VDALLSCGA 306
>30978
          Length = 566

 Score = 30.4 bits (67), Expect = 3.8,   Method: Compositional matrix adjust.
 Identities = 18/51 (35%), Positives = 27/51 (52%), Gaps = 1/51 (1%)
 Frame = -2

Query: 943 GEFDLVQRIIYE-VDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVN 992
           G  D +Q ++ E   + ++ N  G TALH+A    H E VK L+  G  V+
Sbjct: 439 GHMDCLQVLLSEPKCEVNVQNKLGDTALHSAAWKNHVEAVKMLLGKGARVD 287
>11888
          Length = 415

 Score = 30.4 bits (67), Expect = 4.0,   Method: Compositional matrix adjust.
 Identities = 14/41 (34%), Positives = 21/41 (51%)
 Frame = +3

Query: 668 IYSCSQGKPGSPEPETETVSSVHESHENERIPRPLSPTKLL 708
           +   S G P  P  E +T  SVH  H+ E++P P+    +L
Sbjct: 180 VVQLSSGSPLRPVQEVQTGVSVHGLHDGEQLPWPIKNIGVL 302
>33484
          Length = 436

 Score = 30.0 bits (66), Expect = 6.1,   Method: Compositional matrix adjust.
 Identities = 22/70 (31%), Positives = 32/70 (45%), Gaps = 1/70 (1%)
 Frame = -2

Query: 950  RIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDG-WTPLHCAASC 1008
            R +YE        +EG + L  A  AG+ E+ + L+    NV      G  TPL  AAS 
Sbjct: 222  RKLYESGSVPDTTEEGESLLSLACSAGYYELAQVLLAMNANVEDRGIKGDCTPLMEAASG 43

Query: 1009 NNVQVCKFLV 1018
              V + + L+
Sbjct: 42   GFVDIVRLLI 13
>02689
          Length = 798

 Score = 29.6 bits (65), Expect = 7.0,   Method: Composition-based stats.
 Identities = 20/76 (26%), Positives = 36/76 (47%), Gaps = 1/76 (1%)
 Frame = -3

Query: 999  WTPLH-CAASCNNVQVCKFLVESGAAVFAMTYSDMQTAADKCEEMEEGYTQCSQFLYGVQ 1057
            +T +H CA +C +  +CK LVES   +  +  +  Q+           + +  +F  G Q
Sbjct: 430  YTYVHACAHTCKHTHMCKNLVES--KII*L*KAQ*QSVL-----THHSFFKGPEFDLGKQ 272

Query: 1058 EKMGIMNKGVIYALWD 1073
                ++ KG+ Y +WD
Sbjct: 271  PPSPLLGKGIYYDIWD 224
>11861
          Length = 586

 Score = 29.3 bits (64), Expect = 8.3,   Method: Composition-based stats.
 Identities = 15/44 (34%), Positives = 21/44 (47%)
 Frame = -1

Query: 959  SLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPL 1002
            S+ N     ALH A      +IV   +  G ++N  D  G+TPL
Sbjct: 505  SMGNQHRCIALHEAAKRHQWDIVDHCLTHGADINKVDEQGFTPL 374
>10881
          Length = 534

 Score = 29.3 bits (64), Expect = 8.8,   Method: Composition-based stats.
 Identities = 15/51 (29%), Positives = 27/51 (52%), Gaps = 4/51 (7%)
 Frame = -3

Query: 243 ELTRQLEMLKNGRIDGHHDNQSAVAELDRLYKE----LQLRNKLNQEQNAK 289
           ++   L +LKN  +DG H+   +   +D+  K+     QL+  LNQ+  +K
Sbjct: 358 KMLHDLMILKNTYLDGEHETNISTYPIDKQTKQKIFFKQLKKMLNQKNTSK 206
>03590
          Length = 1068

 Score = 29.3 bits (64), Expect = 8.9,   Method: Compositional matrix adjust.
 Identities = 15/44 (34%), Positives = 23/44 (52%), Gaps = 6/44 (13%)
 Frame = +3

Query: 967  TALHNAVCAGH------TEIVKFLVQFGVNVNAADSDGWTPLHC 1004
            T LH AV          T + +FL++   +V A + DG+ P+HC
Sbjct: 771  TVLHTAVSNNRGDANDSTALEEFLLEHKADVFAKNDDGYMPIHC 902
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|15617203|ref|NP_254279.1| chloride intracellular
channel 1 [Mus musculus]
         (241 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

08339                                                                  70   6e-13
14769                                                                  27   6.6  
>08339
          Length = 2500

 Score = 70.5 bits (171), Expect = 6e-13,   Method: Compositional matrix adjust.
 Identities = 68/243 (27%), Positives = 102/243 (41%), Gaps = 29/243 (11%)
 Frame = +1

Query: 22  GNCPFSQRLFMVLWLKGVTFNVTTVDTKRRTETVQKLCPGGQL----------PFL---- 67
           G+CP  Q  FM+  L G   N    D   +  TVQ  CP              P +    
Sbjct: 55  GSCPVCQHWFMITCLLGDRQN----DIDFKVYTVQADCPPKNFGVEQGWSKLFPVVMVLE 222

Query: 68  --------LYGTEVHTDTNKIEEFLEAMLCPPRYPKLAALNPESNTSGL----DIFAKFS 115
                   L GT+  T  +++E F E++     YP L   N   N   +    D++  F+
Sbjct: 223 GCDKKGQDLAGTKYDT-FDELETFFESI--NREYPALKRHN-APNVGAMKVVEDVYTAFN 390

Query: 116 AYIKNSNPALNDNLEKGLLKALKVLDNYLTSPLPEEVDETSAEDEGISQRKFLDGNELTL 175
             +   +P       K L+  L+ ++ +L               E  S  KFL  + ++ 
Sbjct: 391 KCLSTKDP-------KRLMTQLRKINEFL---------------EEESDSKFLVDDVMSF 504

Query: 176 ADCNLLPKLHIVQVVCKKYRGFT---IPEAFRGVHRYLSNAYAREEFASTCPDDEEIELA 232
           ADC+LLP+L  ++V  K Y   T   IP+ F  + RYL+ AY  E F ST P D++I   
Sbjct: 505 ADCHLLPRLQHIRVAGKFYMKDTFDDIPKEFTAIWRYLAEAYKTEAFRSTVPSDQDILFH 684

Query: 233 YEQ 235
           YE+
Sbjct: 685 YEK 693
>14769
          Length = 1139

 Score = 26.9 bits (58), Expect = 6.6,   Method: Compositional matrix adjust.
 Identities = 15/44 (34%), Positives = 23/44 (52%)
 Frame = -1

Query: 34  LWLKGVTFNVTTVDTKRRTETVQKLCPGGQLPFLLYGTEVHTDT 77
           +W+  VT     V   R T++++K  PG + P  L+G  V T T
Sbjct: 767 VWIGRVTSVQQCVSRARETKSLRKKRPGSRQPRTLWGQCVLTGT 636
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|12963603|ref|NP_075736.1| nuclear protein E3-3 [Mus
musculus]
         (185 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

33655                                                                  70   7e-13
26394                                                                  28   3.0  
29019                                                                  27   4.5  
01200                                                                  27   6.8  
>33655
          Length = 268

 Score = 69.7 bits (169), Expect = 7e-13,   Method: Compositional matrix adjust.
 Identities = 33/83 (39%), Positives = 52/83 (62%), Gaps = 1/83 (1%)
 Frame = +3

Query: 41  ELYQRTRISLLQSEFPQAVYIDSYSSRGFTIC-GNRVFGPCVLLPQTVVQWNVGSHQDIT 99
           E  + T +SLL  E    +Y+++YS  GF +  G R+ GPCVL P++++ W VG   ++ 
Sbjct: 6   ESIKSTTVSLLSQEDDDYLYVEAYSPVGFRLTNGFRIIGPCVLFPRSILHWGVGGCHELN 185

Query: 100 EESFSLFWMLEPRIEIVVVGTGN 122
           E+S SLF MLEP++    +G G+
Sbjct: 186 EQSLSLFPMLEPKLAS*SLGVGD 254
>26394
          Length = 518

 Score = 27.7 bits (60), Expect = 3.0,   Method: Compositional matrix adjust.
 Identities = 9/32 (28%), Positives = 17/32 (53%)
 Frame = +2

Query: 81  VLLPQTVVQWNVGSHQDITEESFSLFWMLEPR 112
           +L+P++ + W +  HQ +T    +  W   PR
Sbjct: 110 ILIPRSTIAW*LTQHQTLTSTKAASRWTASPR 205
>29019
          Length = 1188

 Score = 26.9 bits (58), Expect = 4.5,   Method: Compositional matrix adjust.
 Identities = 16/62 (25%), Positives = 27/62 (43%)
 Frame = -1

Query: 42  LYQRTRISLLQSEFPQAVYIDSYSSRGFTICGNRVFGPCVLLPQTVVQWNVGSHQDITEE 101
           L+  ++ISL    FP   ++ +  S  F+ C   V   C  LP  +   N  +  D++  
Sbjct: 795 LFVPSKISLRLFSFPFLYFLTASDSSFFSCCRFXVTSCCTFLPYFLASRNFLAFSDLSML 616

Query: 102 SF 103
            F
Sbjct: 615 VF 610
>01200
          Length = 2147

 Score = 26.6 bits (57), Expect = 6.8,   Method: Compositional matrix adjust.
 Identities = 11/27 (40%), Positives = 17/27 (62%), Gaps = 2/27 (7%)
 Frame = -1

Query: 70  TICGNRVFGPCVLLPQTVVQW--NVGS 94
           T+  NR+FGPC +    + +W  +VGS
Sbjct: 983 TVITNRMFGPCEIFKLDITKWLLSVGS 903
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|149234349|ref|XP_129509.7| PREDICTED:
centrosome-associated protein 350 isoform 1 [Mus musculus]
         (3092 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

26691                                                                  74   8e-13
20779                                                                  69   3e-11
26569                                                                  66   2e-10
10547                                                                  64   1e-09
20604                                                                  62   5e-09
18826                                                                  57   1e-07
31468                                                                  45   5e-04
17755                                                                  32   3.5  
>26691
          Length = 395

 Score = 74.3 bits (181), Expect = 8e-13,   Method: Compositional matrix adjust.
 Identities = 32/65 (49%), Positives = 41/65 (63%)
 Frame = +2

Query: 2483 IGDRVLIGSVQPGTLRFKGETDFAKGFWAGVELDKPEGNNNGTYDGIVYFVCKDKHGIFA 2542
            +G R+LI  V+PG LRF G+T  A G+W G+EL    G ++G  DG  YF CK   GIFA
Sbjct: 134  VGKRILISGVKPGVLRFVGQTSLAPGYWCGIELFDASGLHDGEVDGRRYFTCKPFRGIFA 313

Query: 2543 PPQKI 2547
            P  K+
Sbjct: 314  PLDKV 328
>20779
          Length = 490

 Score = 68.9 bits (167), Expect = 3e-11,   Method: Compositional matrix adjust.
 Identities = 28/50 (56%), Positives = 34/50 (68%)
 Frame = +3

Query: 2499 FKGETDFAKGFWAGVELDKPEGNNNGTYDGIVYFVCKDKHGIFAPPQKIS 2548
            + GET FA G W GVELD+  G N+GT DGI YF CK + G+F P  K+S
Sbjct: 3    YLGETQFAPGNWCGVELDEGSGKNDGTVDGIRYFECKPRFGVFVPIAKVS 152
>26569
          Length = 1180

 Score = 66.2 bits (160), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 33/55 (60%), Positives = 41/55 (74%)
 Frame = +3

Query: 1838 KSMRSRMDEKFLTKREQKLMQRRQHAEELLEWKRRLDAEEAEIQQMEKQALAAWD 1892
            K  R R+D K+LT REQKLM RR+ A ELL WKR LDAEE ++ Q+E+ AL AW+
Sbjct: 420  KQQRLRLDHKYLTSREQKLMARRKQASELLRWKRDLDAEEEKVLQLERTALEAWE 584
>10547
          Length = 856

 Score = 63.9 bits (154), Expect = 1e-09,   Method: Composition-based stats.
 Identities = 28/70 (40%), Positives = 43/70 (61%)
 Frame = +2

Query: 2495 GTLRFKGETDFAKGFWAGVELDKPEGNNNGTYDGIVYFVCKDKHGIFAPPQKISHLLENF 2554
            GT+R+ GETDF  G W G++ D+P G N+G+  G  YF C+ K+G F  P  +   + +F
Sbjct: 8    GTVRYVGETDFKPGMWVGIQYDEPHGKNDGSVAGKRYFECQPKYGGFVKPSNVE--VGDF 181

Query: 2555 DDTDINEDEE 2564
             + D+  DE+
Sbjct: 182  PEEDLGFDED 211
>20604
          Length = 678

 Score = 61.6 bits (148), Expect = 5e-09,   Method: Composition-based stats.
 Identities = 26/47 (55%), Positives = 32/47 (68%)
 Frame = +3

Query: 2501 GETDFAKGFWAGVELDKPEGNNNGTYDGIVYFVCKDKHGIFAPPQKI 2547
            G   FA G W GVELD+PEG N+G+  GI YF C+ +HGIF  P K+
Sbjct: 114  GTCAFAVGNWIGVELDQPEGKNDGSVKGIRYFNCRGRHGIFVRPDKL 254
>18826
          Length = 490

 Score = 57.0 bits (136), Expect = 1e-07,   Method: Composition-based stats.
 Identities = 28/62 (45%), Positives = 37/62 (59%)
 Frame = +3

Query: 2481 FHIGDRVLIGSVQPGTLRFKGETDFAKGFWAGVELDKPEGNNNGTYDGIVYFVCKDKHGI 2540
            F IG RV +G ++ G + + GET FA G WAG+ LD+P G       G  YF C+ K GI
Sbjct: 252  FIIGQRVWVGGLRSGQIAYIGETHFAPGDWAGIVLDEPNGKKRWMRFGQRYFQCEPKRGI 431

Query: 2541 FA 2542
            F+
Sbjct: 432  FS 437
>31468
          Length = 347

 Score = 45.1 bits (105), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 19/33 (57%), Positives = 26/33 (78%)
 Frame = +2

Query: 1838 KSMRSRMDEKFLTKREQKLMQRRQHAEELLEWK 1870
            K  + R+D+K+LT REQKLM+R++ A ELL WK
Sbjct: 152  KQQKLRLDQKYLTVREQKLMERKKQASELLRWK 250
>17755
          Length = 769

 Score = 32.3 bits (72), Expect = 3.5,   Method: Composition-based stats.
 Identities = 20/54 (37%), Positives = 30/54 (55%)
 Frame = -3

Query: 181 QPSVISDTVVRFLNDGPAIDALHSSECLMKMGVHVRTEDEMPNRTKGSENNSKP 234
           Q S+ISDT+ RF      + A+  S   + + VHV T+D+ P   + S +N KP
Sbjct: 302 Q*SMISDTLSRF-----KMVAICVSRANLSLTVHVVTDDKYPTNARSSLSNCKP 156
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|18079334|ref|NP_077128.2|
coiled-coil-helix-coiled-coil-helix domain containing 2 [Mus musculus]
         (153 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

33924                                                                  69   8e-13
39614                                                                  60   3e-10
>33924
          Length = 664

 Score = 68.9 bits (167), Expect = 8e-13,   Method: Compositional matrix adjust.
 Identities = 41/97 (42%), Positives = 53/97 (54%), Gaps = 1/97 (1%)
 Frame = +1

Query: 52  QPGLMAQMXXXXXXXXXXXXXXXXLGHAITGGFSGGGSAEPAKPDITYQEPQGAQLQ-NQ 110
           QPGL AQM                +G A+TG    GGS +  +        Q  ++Q  Q
Sbjct: 244 QPGLFAQMATTAAGVAVGSAVGHTIGAAMTGS---GGSQQQPQEAAAPAPAQINEVQPQQ 414

Query: 111 QSFGPCSLEIKQFLECAQNQSDVKLCEGFNEVLRQCR 147
           Q++ PC  E++QFL+CAQ QSDV LC GFNE LRQC+
Sbjct: 415 QAYNPCQRELQQFLDCAQGQSDVALCAGFNEALRQCK 525
>39614
          Length = 450

 Score = 60.5 bits (145), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 35/81 (43%), Positives = 46/81 (56%), Gaps = 4/81 (4%)
 Frame = -2

Query: 76  LGHAITGGFSGGGSAEPAKPDITYQEPQGAQLQN----QQSFGPCSLEIKQFLECAQNQS 131
           +GH I    SGGG  E       YQEP  A        +Q + PC  E+++FL CAQ Q+
Sbjct: 407 VGHTIGAAMSGGGGRE-------YQEPAAAPAPVAQQQEQVYNPCQRELQEFLHCAQGQA 249

Query: 132 DVKLCEGFNEVLRQCRIANGL 152
           D+ LC GFNE LRQC++  G+
Sbjct: 248 DLGLCAGFNEALRQCKLQFGI 186
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|7709982|ref|NP_057875.1| aryl-hydrocarbon
receptor-interacting protein [Mus musculus]
         (330 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

00888                                                                  70   9e-13
03857                                                                  68   5e-12
35264                                                                  39   0.004
08670                                                                  38   0.005
35348                                                                  38   0.006
35341                                                                  32   0.26 
01124                                                                  29   2.3  
37162                                                                  29   3.1  
27270                                                                  28   7.4  
>00888
          Length = 970

 Score = 70.5 bits (171), Expect = 9e-13,   Method: Compositional matrix adjust.
 Identities = 48/186 (25%), Positives = 91/186 (48%), Gaps = 2/186 (1%)
 Frame = -3

Query: 147 PLIFHIEMLKVESPGTYQQDPWAMTDEEKAKAVPVIHQEGNRLYREGQVKEAAAKYYDAI 206
            L++++EM+  E      +  W M   EK +   +I ++G   +++G+ + A   Y   +
Sbjct: 824 TLVYNVEMVNFEKA----KQSWEMDVGEKIEQSKIIKEKGTAAFKKGKYQRALTNYEKIV 657

Query: 207 ACLKNLQMKEQPGSPDWIQLDLQ--ITPLLLNYCQCKLVAQEYYEVLDHCSSILNKYDDN 264
           + L++    E  G  D    D    +    LN   C+L   +Y +  + C+ +L    +N
Sbjct: 656 SFLEH----ESTGLSDSELSDKHQLMVAAFLNIAMCQLKLLDYRQAEETCNKVLAMSTNN 489

Query: 265 VKAYFKRGKAHAAVWNAQEAQADFAKVLELDPALAPVVSRELRALETRIRQKDEEDKARF 324
           VKA F+RG+A     +  EA +DF+KVLEL+P      ++ +  L     QK + D A+ 
Sbjct: 488 VKALFRRGQARLECADYTEAASDFSKVLELEPGNKAAKNQHIVCL-----QKQKADYAKE 324

Query: 325 RGIFSH 330
           + ++++
Sbjct: 323 KALYTN 306
>03857
          Length = 1696

 Score = 68.2 bits (165), Expect = 5e-12,   Method: Compositional matrix adjust.
 Identities = 72/249 (28%), Positives = 116/249 (46%), Gaps = 10/249 (4%)
 Frame = +1

Query: 91  DIKHVVLYPLVA-----KSLRNI-AEGKDPLEGQRHCCGIAQMHEHSSLGHADLDALQQN 144
           D KHVV   ++A     + L N+  +G+ P +     C IA   E +    AD D    N
Sbjct: 214 DGKHVVFGEVIAGHNVVRELENVDKDGETPTK----TCSIADCGELA----ADCDVTTFN 369

Query: 145 PQPLIFHIEMLKVESPGTYQQDPWAMT-DEEKAKAVPVIHQEGNRLYREGQVKEAAAKYY 203
                     +  + PG    D  A +  EE  K V  + Q GN L++ G+   A  KY 
Sbjct: 370 KD----DSGDVHADYPGDSSIDFTADSCGEEVRKVVLDVKQAGNTLFKAGKFGPANRKYK 537

Query: 204 DAIACLKNLQMKEQPGSPDW---IQLDLQITPLLLNYCQCKLVAQEYYEVLDHCSSILNK 260
            A+  L+ L  +EQ  S D    ++ +L I P+ LN   C L   +Y E L++C  +L  
Sbjct: 538 KALRYLQKLD-EEQKMSEDQQKAMEKELHI-PVSLNAAACCLKLNKYNEALEYCQEVLEA 711

Query: 261 YDDNVKAYFKRGKAHAAVWNAQEAQADFAKVLELDPALAPVVSRELRALETRIRQKDEED 320
             DN KA +++G+AHA   + + A A F K L  +P       + ++    ++++  EE+
Sbjct: 712 DPDNSKAQYRQGQAHAGNKDYETALASFQKALAANPD-----DKGIKLEIQKVKRTVEEE 876

Query: 321 KARFRGIFS 329
           K R + ++S
Sbjct: 877 KKREKQMYS 903
>35264
          Length = 867

 Score = 38.5 bits (88), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 19/54 (35%), Positives = 31/54 (57%), Gaps = 5/54 (9%)
 Frame = +3

Query: 265 VKAYFKRGKAHAAVWNAQEAQADFAKVLELDPALAPVVS-----RELRALETRI 313
           VK Y + GK H  + N+  A ++F +VLELD   +  V+     + L+ LET++
Sbjct: 243 VKGYIREGKCHLMLGNSMAASSNFNRVLELDAGNSTAVTELKRVKTLQELETKV 404
>08670
          Length = 1307

 Score = 38.1 bits (87), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 28/89 (31%), Positives = 42/89 (47%)
 Frame = +3

Query: 224 IQLDLQITPLLLNYCQCKLVAQEYYEVLDHCSSILNKYDDNVKAYFKRGKAHAAVWNAQE 283
           I LD +    L N   C    Q+Y + L      +    D  K YF++G+A A +    E
Sbjct: 453 IALDPKDFRFLGNRSYCYDRLQQYEKALKDAEKAIKLSKDWPKGYFRKGRALAGLCKFSE 632

Query: 284 AQADFAKVLELDPALAPVVSRELRALETR 312
           A+  F +VL+LD      V +EL+ + TR
Sbjct: 633 AEESFLQVLKLDKNCEEAV-QELQQVRTR 716
>35348
          Length = 627

 Score = 37.7 bits (86), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 37/143 (25%), Positives = 65/143 (45%), Gaps = 2/143 (1%)
 Frame = -2

Query: 176 AKAVPVIHQEGNRLYREGQVKEAAAKYYDA--IACLKNLQMKEQPGSPDWIQLDLQITPL 233
           A+AV V    GN  ++ GQ  EA   Y +   I  LK +Q               Q + +
Sbjct: 590 AEAVKV-KVRGNDTFKSGQYAEALELYSEGLDICPLKYVQ---------------QRSVM 459

Query: 234 LLNYCQCKLVAQEYYEVLDHCSSILNKYDDNVKAYFKRGKAHAAVWNAQEAQADFAKVLE 293
           L N   C++  ++Y + +  C+  ++     +KAYF+R  A+  +    +A  D  +V+E
Sbjct: 458 LSNRAACRIKKEDYQKAVGDCTKSIDLNPAYIKAYFRRADAYEKLEKLDDALKDHRQVVE 279

Query: 294 LDPALAPVVSRELRALETRIRQK 316
           +D +    +   LR LE  I ++
Sbjct: 278 MDRSQIDSIQACLR-LEKEIEER 213
>35341
          Length = 641

 Score = 32.3 bits (72), Expect = 0.26,   Method: Compositional matrix adjust.
 Identities = 23/73 (31%), Positives = 36/73 (49%), Gaps = 2/73 (2%)
 Frame = +3

Query: 226 LDLQITPLLLNYCQC-KLVAQEYYEVLD-HCSSILNKYDDNVKAYFKRGKAHAAVWNAQE 283
           +DL  T  LL   +   L+  E Y V +  C++ +      VKAY +R  A   +   Q 
Sbjct: 3   MDLDPTNALLPANRAMALIKMEKYGVAEVDCTTAITLDPLYVKAYLRRAAARVGMQRLQP 182

Query: 284 AQADFAKVLELDP 296
           A  D+ +VL+L+P
Sbjct: 183 ALEDYERVLQLEP 221
>01124
          Length = 1372

 Score = 29.3 bits (64), Expect = 2.3,   Method: Compositional matrix adjust.
 Identities = 19/81 (23%), Positives = 35/81 (43%), Gaps = 8/81 (9%)
 Frame = -3

Query: 224 IQLDLQITPLLLNYCQCKLVAQEYYEVLDHCSSILN--------KYDDNVKAYFKRGKAH 275
           ++L+ ++  L  N   C L  +  ++ ++ CS  ++             VKA  +RG A 
Sbjct: 674 LRLNPKMPSLYSNRAACHLKLRNLFKCIEDCSKAMDLLSPPVPQNAASRVKAMVRRGTAF 495

Query: 276 AAVWNAQEAQADFAKVLELDP 296
             +    E   D+   L+LDP
Sbjct: 494 CQLEMYVEGLQDYEAALKLDP 432
>37162
          Length = 601

 Score = 28.9 bits (63), Expect = 3.1,   Method: Compositional matrix adjust.
 Identities = 15/51 (29%), Positives = 26/51 (50%), Gaps = 1/51 (1%)
 Frame = -2

Query: 25  LPDFQDGTKATFHFRTLHSDNEGSVIDDSRTRGK-PMELIVGKKFKLPVWE 74
           + D +DG     H+        G+V D S   G+ P+E ++G++  +P WE
Sbjct: 600 IGDIRDGDGVAVHYTGYL--ETGAVFDSSVQAGREPLEFLLGERKVIPGWE 454
>27270
          Length = 1078

 Score = 27.7 bits (60), Expect = 7.4,   Method: Compositional matrix adjust.
 Identities = 16/55 (29%), Positives = 27/55 (49%), Gaps = 2/55 (3%)
 Frame = +3

Query: 33  KATFHFRTLHSDNEGSV--IDDSRTRGKPMELIVGKKFKLPVWETIVCTMREGEI 85
           K      T H   E +V  +  +  RG+   +++    + PV+ET+V   R+GEI
Sbjct: 837 KTVVRLTTAHGKGETTVPVLAAAPCRGQSSLVVMHGSHQQPVFETVVLRPRQGEI 1001
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|13384872|ref|NP_079737.1| hypothetical protein
LOC66272 [Mus musculus]
         (106 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

31716                                                                  45   1e-12
22906                                                                  26   3.8  
>31716
          Length = 485

 Score = 44.7 bits (104), Expect(2) = 1e-12,   Method: Compositional matrix adjust.
 Identities = 15/31 (48%), Positives = 25/31 (80%)
 Frame = +1

Query: 12 KNKTLRYGVPMLLLVVGGSFGLREFSQIRYD 42
          K + +R+G+P ++ +VGGSF L++F+ IRYD
Sbjct: 67 KRRFIRFGIPFIVCIVGGSFALKQFATIRYD 159

 Score = 43.1 bits (100), Expect(2) = 1e-12,   Method: Compositional matrix adjust.
 Identities = 16/33 (48%), Positives = 26/33 (78%)
 Frame = +3

Query: 62  TLESEYEKIKDSTFENWKNIRGPRPWEDPQLLQ 94
           T+E+ YE++++   + W+NIRGPRPWED + +Q
Sbjct: 234 TIEAAYEELENKDLDMWENIRGPRPWEDSKTVQ 332
>22906
          Length = 853

 Score = 26.2 bits (56), Expect = 3.8,   Method: Compositional matrix adjust.
 Identities = 15/53 (28%), Positives = 25/53 (47%), Gaps = 2/53 (3%)
 Frame = +2

Query: 20  VPMLLLVVGGSFGLREFSQIRYDAVTIK--IDPELEKKLKVNKITLESEYEKI 70
           VPM++      F L E S   YD V +   + P   ++L   K+TL+   + +
Sbjct: 461 VPMIVFCKDVHFALEELSHSGYDVVGLDWTMPPLHARRLVGTKVTLQGNMDPV 619
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|169881259|ref|NP_061222.3| transient receptor
potential cation channel, subfamily M, member 1 isoform 1 [Mus
musculus]
         (542 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

33604                                                                  70   1e-12
01886                                                                  30   3.3  
25591                                                                  28   9.7  
>33604
          Length = 717

 Score = 70.5 bits (171), Expect = 1e-12,   Method: Compositional matrix adjust.
 Identities = 45/148 (30%), Positives = 74/148 (50%), Gaps = 20/148 (13%)
 Frame = +1

Query: 203 PVPVVVCDGSGRASDILSFAHKY----------------CDEGGVINESLRDQLLVTIQK 246
            +PVVVC G+GRA+D L++AHK+                 D GG   +S++ +L    ++
Sbjct: 34  AIPVVVCTGTGRAADFLTYAHKFTFKDRNRCLHNERTSEADTGGSCGKSVQ*KLGQCGRR 213

Query: 247 TFNYSKSQSYQLFAIIMECMKKKELVTVFRMGSEGQQDVEMAILTALLKGTNASAP---- 302
                  Q  +++       ++++    F +  E  +D+++AIL+ L K   AS      
Sbjct: 214 RTEECHGQDRRVY-------EERQSDDFFDLRRE--EDLDVAILSVLTKAETASGAKHRL 366

Query: 303 DQLSLALAWNRVDIARSQIFVFGPHWPP 330
           +QL LAL WNR DIA+S+IF    +W  
Sbjct: 367 NQLELALTWNRADIAQSEIFREDVNWSA 450

 Score = 48.5 bits (114), Expect = 6e-06,   Method: Compositional matrix adjust.
 Identities = 23/51 (45%), Positives = 37/51 (72%), Gaps = 1/51 (1%)
 Frame = +1

Query: 382 ELLNW-VNALEQAMLDALVLDRVDFVKLLIENGVNMQHFLTIPRLEELYNT 431
           E +NW  + L   M  AL  D+++FV+LL+  GV+M+ +LT+PR+E+LYN+
Sbjct: 430 EDVNWSADDLFMIMTKALKEDKMNFVRLLLNQGVSMKEYLTVPRMEDLYNS 582
>01886
          Length = 3921

 Score = 29.6 bits (65), Expect = 3.3,   Method: Compositional matrix adjust.
 Identities = 14/40 (35%), Positives = 21/40 (52%)
 Frame = +2

Query: 82   LKDHSSKSRGRLCAIGIAPWGMVENKEDLIGKDVTRVYQT 121
            ++D   +  G L   G+  WG+VENK  L  +  TR + T
Sbjct: 1007 IQDFQYRQHGDLIFGGLQWWGVVENKAKLAAQLKTRSFAT 1126
>25591
          Length = 1307

 Score = 28.1 bits (61), Expect = 9.7,   Method: Compositional matrix adjust.
 Identities = 19/58 (32%), Positives = 28/58 (48%), Gaps = 9/58 (15%)
 Frame = -3

Query: 121  TMSNPLSKLSVLNNSHTHFILADNGTLGKYGAEVKLRRQ---------LEKHISLQKI 169
            T+ NPL K    + +HTH  L  +  L +Y ++  L RQ          ++H SL KI
Sbjct: 1233 TIQNPLVKYRFTDKTHTHT*LFSSLVLFQYLSDTSLWRQDV*NWGILNKQRHKSLSKI 1060
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|27819594|ref|NP_034982.1| myelin basic protein
expression factor 2, repressor [Mus musculus]
         (530 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

08816                                                                  70   1e-12
02064                                                                  68   9e-12
31938                                                                  58   7e-09
23720                                                                  56   3e-08
17775                                                                  56   5e-08
04988                                                                  51   1e-06
30672                                                                  50   3e-06
02415                                                                  43   3e-04
37645                                                                  42   5e-04
03059                                                                  42   6e-04
13822                                                                  42   6e-04
28652                                                                  42   9e-04
12350                                                                  41   0.001
25691                                                                  41   0.001
03200                                                                  38   0.008
16427                                                                  38   0.011
03406                                                                  37   0.013
10194                                                                  37   0.020
26197                                                                  37   0.024
25746                                                                  37   0.027
11687                                                                  36   0.033
24983                                                                  35   0.060
02343                                                                  34   0.12 
17681                                                                  33   0.20 
19733                                                                  32   0.46 
12215                                                                  32   0.59 
32386                                                                  31   1.1  
03000                                                                  30   1.9  
11019                                                                  30   2.1  
25950                                                                  30   2.3  
33516                                                                  30   3.4  
07622                                                                  29   4.3  
03903                                                                  29   4.6  
19980                                                                  29   6.1  
>08816
          Length = 566

 Score = 70.5 bits (171), Expect = 1e-12,   Method: Compositional matrix adjust.
 Identities = 33/82 (40%), Positives = 50/82 (60%)
 Frame = +1

Query: 445 RDRLGSKGNQIFVRNLPFDLTWQKLKEKFSQCGHVMFAEIKMENGKSKGCGTVRFESAES 504
           R + G     + VRN+PF LTWQ+L+E+F   G V F+EI M+ G+  G   VRF ++  
Sbjct: 25  RAQQGQARCTVTVRNVPFSLTWQELRERFQDIGDVKFSEILMDQGRPSGDAVVRFGTSAD 204

Query: 505 AEKACRIMNGIKISGREIDVRL 526
           A +A  +++G +I GR + V L
Sbjct: 205 AMRAINLVDGTRIDGRTVRVVL 270

 Score = 40.0 bits (92), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 19/80 (23%), Positives = 43/80 (53%)
 Frame = +1

Query: 41  KKGPNRNRVFISNIPYDMKWQAIKDLMREKVGEVTYVELFKDAEGKSRGCGVVEFKDEEF 100
           ++G  R  V + N+P+ + WQ +++  ++ +G+V + E+  D +G+  G  VV F     
Sbjct: 31  QQGQARCTVTVRNVPFSLTWQELRERFQD-IGDVKFSEILMD-QGRPSGDAVVRFGTSAD 204

Query: 101 VKKALETMNKYDLSGRPLNI 120
             +A+  ++   + GR + +
Sbjct: 205 AMRAINLVDGTRIDGRTVRV 264
>02064
          Length = 1195

 Score = 68.2 bits (165), Expect = 9e-12,   Method: Compositional matrix adjust.
 Identities = 30/74 (40%), Positives = 48/74 (64%)
 Frame = +1

Query: 455 IFVRNLPFDLTWQKLKEKFSQCGHVMFAEIKMENGKSKGCGTVRFESAESAEKACRIMNG 514
           + V+NLP+ +TWQ L+E+F + G V ++EI M+ G+S G G VRF + + A +A   M+ 
Sbjct: 85  VQVKNLPYAITWQDLRERFQEIGVVKYSEITMDKGRSTGQGLVRFATEDDAVRAINSMDR 264

Query: 515 IKISGREIDVRLDR 528
            +  GR I V++ R
Sbjct: 265 TRYEGRTIGVKMYR 306

 Score = 50.1 bits (118), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 25/78 (32%), Positives = 46/78 (58%)
 Frame = +1

Query: 44  PNRNRVFISNIPYDMKWQAIKDLMREKVGEVTYVELFKDAEGKSRGCGVVEFKDEEFVKK 103
           P+   V + N+PY + WQ +++  +E +G V Y E+  D +G+S G G+V F  E+   +
Sbjct: 70  PDNCTVQVKNLPYAITWQDLRERFQE-IGVVKYSEITMD-KGRSTGQGLVRFATEDDAVR 243

Query: 104 ALETMNKYDLSGRPLNIK 121
           A+ +M++    GR + +K
Sbjct: 244 AINSMDRTRYEGRTIGVK 297
>31938
          Length = 746

 Score = 58.2 bits (139), Expect = 7e-09,   Method: Compositional matrix adjust.
 Identities = 29/74 (39%), Positives = 40/74 (54%)
 Frame = +3

Query: 451 KGNQIFVRNLPFDLTWQKLKEKFSQCGHVMFAEIKMENGKSKGCGTVRFESAESAEKACR 510
           K + I ++N+P   TWQ L++KF   G V FAEI     +    G VRF     AE A  
Sbjct: 255 KSDTIVIKNVPLSCTWQTLRDKFRDVGDVKFAEI-----RGNDVGVVRFFKERDAELAIA 419

Query: 511 IMNGIKISGREIDV 524
           +M+G ++ GR I V
Sbjct: 420 LMDGSRLDGRTIKV 461

 Score = 38.1 bits (87), Expect = 0.009,   Method: Compositional matrix adjust.
 Identities = 21/72 (29%), Positives = 35/72 (48%)
 Frame = +3

Query: 49  VFISNIPYDMKWQAIKDLMREKVGEVTYVELFKDAEGKSRGCGVVEFKDEEFVKKALETM 108
           + I N+P    WQ ++D  R+ VG+V + E+      +    GVV F  E   + A+  M
Sbjct: 267 IVIKNVPLSCTWQTLRDKFRD-VGDVKFAEI------RGNDVGVVRFFKERDAELAIALM 425

Query: 109 NKYDLSGRPLNI 120
           +   L GR + +
Sbjct: 426 DGSRLDGRTIKV 461
>23720
          Length = 739

 Score = 56.2 bits (134), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 32/93 (34%), Positives = 52/93 (55%), Gaps = 3/93 (3%)
 Frame = -1

Query: 34  KNSGTGEKKGP---NRNRVFISNIPYDMKWQAIKDLMREKVGEVTYVELFKDAEGKSRGC 90
           + SG G+K GP      R+ + N+   + WQ +KD MR+  GEVTY     DA  + R  
Sbjct: 388 RRSGWGDKYGPPTRTDYRLVVENLSSRVSWQDLKDYMRQ-AGEVTYA----DAHKRHRNE 224

Query: 91  GVVEFKDEEFVKKALETMNKYDLSGRPLNIKED 123
           G++EF     +K AL+ ++  +++GR + + ED
Sbjct: 223 GIIEFATSSDLKNALDKLDNTEINGRKIKLVED 125
>17775
          Length = 1282

 Score = 55.8 bits (133), Expect = 5e-08,   Method: Compositional matrix adjust.
 Identities = 49/184 (26%), Positives = 85/184 (46%)
 Frame = -2

Query: 84  EGKSRGCGVVEFKDEEFVKKALETMNKYDLSGRPLNIKEDPDGENARRALQRTGTSFQGS 143
           +GKSRG G V F++ E  +KA++ +N  ++SGR +       G   +RA ++        
Sbjct: 543 DGKSRGFGFVSFEEPEGAEKAVDEINGTEVSGRIIYC-----GRAQKRAERQA------- 400

Query: 144 HASDVGSGLVXXXXXXXXXXXXXXEVISNLQAGRLGSTIFVANLDFKVGWKKLKEVFSIA 203
                                   E I+  Q    G  ++V NLD  +  ++L++ FS  
Sbjct: 399 -------------ELKERFEKIKLERINRYQ----GVNLYVKNLDDSIDDERLRKEFSNF 271

Query: 204 GTVKRADIKEDKDGKSRGMGTVTFEQAIEAVQAISMFNGQFLFDRPMHVKMDDKSVPHED 263
           GT+  A I  +  G+S+G G V F    EA +A++  NG+ +  +P++V +  +    ED
Sbjct: 270 GTITSAKIMTE-GGRSKGFGFVCFSSPEEATKAVTEMNGRIIVAKPLYVALAQRK---ED 103

Query: 264 YRSH 267
            R+ 
Sbjct: 102 RRAQ 91

 Score = 47.8 bits (112), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 29/76 (38%), Positives = 44/76 (57%)
 Frame = -2

Query: 451 KGNQIFVRNLPFDLTWQKLKEKFSQCGHVMFAEIKMENGKSKGCGTVRFESAESAEKACR 510
           +G  ++V+NL   +  ++L+++FS  G +  A+I  E G+SKG G V F S E A KA  
Sbjct: 348 QGVNLYVKNLDDSIDDERLRKEFSNFGTITSAKIMTEGGRSKGFGFVCFSSPEEATKAVT 169

Query: 511 IMNGIKISGREIDVRL 526
            MNG  I  + + V L
Sbjct: 168 EMNGRIIVAKPLYVAL 121

 Score = 43.9 bits (102), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 22/70 (31%), Positives = 43/70 (61%)
 Frame = -2

Query: 455 IFVRNLPFDLTWQKLKEKFSQCGHVMFAEIKMENGKSKGCGTVRFESAESAEKACRIMNG 514
           +F++NL   +  + L + FS  G+++  +I  +   SKG G V FE+ E+A +A   +NG
Sbjct: 924 VFIKNLDKTIDNKALYDTFSAFGNILSCKIACDEQGSKGYGFVHFETEEAARQAIDKVNG 745

Query: 515 IKISGREIDV 524
           + ++G+++ V
Sbjct: 744 MLLNGKKVYV 715

 Score = 40.8 bits (94), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 31/87 (35%), Positives = 45/87 (51%), Gaps = 8/87 (9%)
 Frame = -2

Query: 444 MRDRLGSKGNQIFVRNL-------PFD-LTWQKLKEKFSQCGHVMFAEIKMENGKSKGCG 495
           M D+L  + N ++V+N        P   L WQ  ++      H+     + E+GKS+G G
Sbjct: 678 MGDKL-KRFNNVYVKNFC*GTG*RPAA*LVWQARQD------HLXXGACRGEDGKSRGFG 520

Query: 496 TVRFESAESAEKACRIMNGIKISGREI 522
            V FE  E AEKA   +NG ++SGR I
Sbjct: 519 FVSFEEPEGAEKAVDEINGTEVSGRII 439

 Score = 29.3 bits (64), Expect = 3.7,   Method: Compositional matrix adjust.
 Identities = 21/74 (28%), Positives = 35/74 (47%), Gaps = 1/74 (1%)
 Frame = -2

Query: 180  STIFVANLDFKVGWKKLKEVFSIAGTVKRADIKEDK-DGKSRGMGTVTFEQAIEAVQAIS 238
            ++++V +L   V    L E FS AG V    +  D    +S G   V F+Q  +A +A+ 
Sbjct: 1194 ASLYVGDLHPDVTEAMLFEKFSTAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALD 1015

Query: 239  MFNGQFLFDRPMHV 252
              N   +  RP+ +
Sbjct: 1014 TMNFDTVKGRPIRI 973

 Score = 28.5 bits (62), Expect = 6.5,   Method: Compositional matrix adjust.
 Identities = 14/28 (50%), Positives = 19/28 (67%)
 Frame = -2

Query: 215 KDGKSRGMGTVTFEQAIEAVQAISMFNG 242
           +DGKSRG G V+FE+   A +A+   NG
Sbjct: 546 EDGKSRGFGFVSFEEPEGAEKAVDEING 463
>04988
          Length = 705

 Score = 51.2 bits (121), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 32/96 (33%), Positives = 52/96 (54%), Gaps = 6/96 (6%)
 Frame = -3

Query: 34  KNSGTGEKKG----PNRN--RVFISNIPYDMKWQAIKDLMREKVGEVTYVELFKDAEGKS 87
           + SG G+K      P R   R+ + N+   + WQ +KD MR+  GEVTY     DA  + 
Sbjct: 355 RRSGWGDKVPRYGPPTRTDYRLVVENLSSRVSWQDLKDYMRQ-AGEVTYA----DAHKRH 191

Query: 88  RGCGVVEFKDEEFVKKALETMNKYDLSGRPLNIKED 123
           R  G++EF     +K AL+ ++  +++GR + + ED
Sbjct: 190 RNEGIIEFATSSDLKNALDKLDNTEINGRKIKLVED 83
>30672
          Length = 877

 Score = 49.7 bits (117), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 56/208 (26%), Positives = 91/208 (43%), Gaps = 4/208 (1%)
 Frame = +3

Query: 49  VFISNIPYDMKWQAIKDLMREKVGEVTYVELFKDAE-GKSRGCGVVEFKDEEFVKKALET 107
           +F+ N+P++   + + +   E+VG +    +    E GK RG G V+F   E   KA +T
Sbjct: 18  LFVRNLPFETSNEKLLEAF-EQVGPLKTAFVVAGKEPGKCRGFGYVQFSMLEDAIKAKDT 194

Query: 108 MNKYDLSGRPLNIKEDPDGENARRALQRTGTSFQGSHASDVGSGLVXXXXXXXXXXXXXX 167
           +     SGR +++    D + + +  Q+ GT  + S A  +G  L               
Sbjct: 195 VT--HCSGRKISL-SFADTKKSWKTKQKGGT--ETSDALGLGKKLPSQTAVTDGEPNPKP 359

Query: 168 EVISNLQAGR-LG--STIFVANLDFKVGWKKLKEVFSIAGTVKRADIKEDKDGKSRGMGT 224
           E     Q  + LG    + + NL FK     ++  F   GT+    I   +  +SRG   
Sbjct: 360 EKKKTKQPKQELGKRCRLIIRNLAFKCKEADIRSHFGKFGTISEVTIPLKQGDRSRGFAF 539

Query: 225 VTFEQAIEAVQAISMFNGQFLFDRPMHV 252
           V F +   A +AIS  NG  + DRP+ V
Sbjct: 540 VQFTEVKAAQKAISDMNGTAIMDRPVAV 623

 Score = 42.4 bits (98), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 29/72 (40%), Positives = 39/72 (54%), Gaps = 2/72 (2%)
 Frame = +3

Query: 455 IFVRNLPFDLTWQKLKEKFSQCGHV--MFAEIKMENGKSKGCGTVRFESAESAEKACRIM 512
           +FVRNLPF+ + +KL E F Q G +   F     E GK +G G V+F   E A KA   +
Sbjct: 18  LFVRNLPFETSNEKLLEAFEQVGPLKTAFVVAGKEPGKCRGFGYVQFSMLEDAIKAKDTV 197

Query: 513 NGIKISGREIDV 524
                SGR+I +
Sbjct: 198 T--HCSGRKISL 227
>02415
          Length = 2763

 Score = 43.1 bits (100), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 30/87 (34%), Positives = 45/87 (51%), Gaps = 2/87 (2%)
 Frame = -1

Query: 442  SGMRDRLGSKGNQIFVRNLPFDLTWQKLKEKFSQCGHVMFAEIKM--ENGKSKGCGTVRF 499
            +G +D   +K   IFV  LP+  T   L+E F + G +  A +    + GKS+G G V  
Sbjct: 1950 TGQKDTTYTK---IFVGGLPYHTTDHSLREYFDKFGDIDEAVVITDRQTGKSRGYGFVTM 1780

Query: 500  ESAESAEKACRIMNGIKISGREIDVRL 526
                 A++AC+  N I I GR+ +V L
Sbjct: 1779 ADRTGADRACKDPNPI-IDGRKANVNL 1702
>37645
          Length = 1070

 Score = 42.4 bits (98), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 26/71 (36%), Positives = 37/71 (52%)
 Frame = -2

Query: 458  RNLPFDLTWQKLKEKFSQCGHVMFAEIKMENGKSKGCGTVRFESAESAEKACRIMNGIKI 517
            R +  DL  Q      +Q GH  +  I ME G+S G G VRF + + A +A   M+  + 
Sbjct: 1057 RPIFADLFLQA*AVVSTQSGH--YGGITMEKGRSMGQGLVRFATEDDAVRAINSMDRTRF 884

Query: 518  SGREIDVRLDR 528
             GR IDV++ R
Sbjct: 883  EGRTIDVKMYR 851
>03059
          Length = 1154

 Score = 42.0 bits (97), Expect = 6e-04,   Method: Compositional matrix adjust.
 Identities = 24/76 (31%), Positives = 41/76 (53%), Gaps = 3/76 (3%)
 Frame = -2

Query: 450 SKGNQIFVRNLPFDLTWQKLKEKFSQCGHVMFAEI---KMENGKSKGCGTVRFESAESAE 506
            K  ++ V  L  ++    ++E FS  G + F ++   ++    SKG   V +E+ E AE
Sbjct: 679 PKPTKVHVGRLTRNVNKDHIQEIFSLYGTIKFIDLPNDRIHPNTSKGHAYVEYENPEDAE 500

Query: 507 KACRIMNGIKISGREI 522
           KA + M+G +I G+EI
Sbjct: 499 KAVKYMDGGQIDGQEI 452

 Score = 35.4 bits (80), Expect = 0.064,   Method: Compositional matrix adjust.
 Identities = 18/65 (27%), Positives = 33/65 (50%), Gaps = 2/65 (3%)
 Frame = -2

Query: 180 STIFVANLDFKVGWKKLKEVFSIAGTVKRADIKEDK--DGKSRGMGTVTFEQAIEAVQAI 237
           + + V  L   V    ++E+FS+ GT+K  D+  D+     S+G   V +E   +A +A+
Sbjct: 670 TKVHVGRLTRNVNKDHIQEIFSLYGTIKFIDLPNDRIHPNTSKGHAYVEYENPEDAEKAV 491

Query: 238 SMFNG 242
              +G
Sbjct: 490 KYMDG 476
>13822
          Length = 963

 Score = 42.0 bits (97), Expect = 6e-04,   Method: Compositional matrix adjust.
 Identities = 24/71 (33%), Positives = 36/71 (50%)
 Frame = -1

Query: 454 QIFVRNLPFDLTWQKLKEKFSQCGHVMFAEIKMENGKSKGCGTVRFESAESAEKACRIMN 513
           ++ V N+PF      L++     G ++  EI      SKG G V F  +  AE+A   MN
Sbjct: 339 RLHVSNIPFRFREADLRQLLGPFGTILDVEIIFNERGSKGFGFVTFAHSAEAERARDKMN 160

Query: 514 GIKISGREIDV 524
           G  + GR+I+V
Sbjct: 159 GTVVEGRKIEV 127
>28652
          Length = 918

 Score = 41.6 bits (96), Expect = 9e-04,   Method: Compositional matrix adjust.
 Identities = 31/75 (41%), Positives = 38/75 (50%)
 Frame = -2

Query: 450 SKGNQIFVRNLPFDLTWQKLKEKFSQCGHVMFAEIKMENGKSKGCGTVRFESAESAEKAC 509
           SK   ++VRNL  D+T   LKEKF   G V   +      K K  G V +E  E A KA 
Sbjct: 209 SKVKVLYVRNLTGDVTEDDLKEKFGAYGKVERVK------KIKDYGFVHYEDREDALKAL 48

Query: 510 RIMNGIKISGREIDV 524
             ++G KI   EIDV
Sbjct: 47  DDLHGEKIGNLEIDV 3
>12350
          Length = 975

 Score = 40.8 bits (94), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 28/78 (35%), Positives = 41/78 (52%), Gaps = 2/78 (2%)
 Frame = -2

Query: 451 KGNQIFVRNLPFDLTWQKLKEKFSQCGHVMFAEIKME--NGKSKGCGTVRFESAESAEKA 508
           K + + V  LP+  T   L+  FSQ G ++  ++K +   G+SKG G +RF   ES  K 
Sbjct: 626 KCSDLIVLGLPWKSTEDDLRSYFSQFGDLLMVQVKKDPKTGQSKGFGFIRFAEYESQLK- 450

Query: 509 CRIMNGIKISGREIDVRL 526
           C     + I GR  DVR+
Sbjct: 449 CMAQRHM-IDGRWCDVRI 399
>25691
          Length = 768

 Score = 40.8 bits (94), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 22/65 (33%), Positives = 37/65 (56%), Gaps = 2/65 (3%)
 Frame = -2

Query: 451 KGNQIFVRNLPFDLTWQKLKEKFSQCGHVMFAEIKME--NGKSKGCGTVRFESAESAEKA 508
           KG  +++  LP  LT   L+  F+ CG+++ + I  +   G SKG G +RF+    AE+A
Sbjct: 266 KGANLYISGLPKSLTQLDLENLFTDCGNIITSRILYDQTTGLSKGVGFIRFDQRIEAERA 87

Query: 509 CRIMN 513
            + +N
Sbjct: 86  IQKLN 72

 Score = 35.0 bits (79), Expect = 0.072,   Method: Compositional matrix adjust.
 Identities = 19/67 (28%), Positives = 36/67 (53%), Gaps = 1/67 (1%)
 Frame = -2

Query: 179 GSTIFVANLDFKVGWKKLKEVFSIAGTVKRADIKEDKD-GKSRGMGTVTFEQAIEAVQAI 237
           G+ ++++ L   +    L+ +F+  G +  + I  D+  G S+G+G + F+Q IEA +AI
Sbjct: 263 GANLYISGLPKSLTQLDLENLFTDCGNIITSRILYDQTTGLSKGVGFIRFDQRIEAERAI 84

Query: 238 SMFNGQF 244
              N   
Sbjct: 83  QKLNNHI 63
>03200
          Length = 657

 Score = 38.1 bits (87), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 27/79 (34%), Positives = 42/79 (53%)
 Frame = -1

Query: 450 SKGNQIFVRNLPFDLTWQKLKEKFSQCGHVMFAEIKMENGKSKGCGTVRFESAESAEKAC 509
           SKG+ ++V  +   +T   LK  FS  G+++   I+ E    +  G V FE  ESA++A 
Sbjct: 495 SKGHTVYVHGI--GVTEDILKSAFSNFGNIVNINIERE----RNNGFVTFEKMESADQAI 334

Query: 510 RIMNGIKISGREIDVRLDR 528
             MNG  IS  ++ V + R
Sbjct: 333 ANMNGSMISNVQLKVMMAR 277

 Score = 28.9 bits (63), Expect = 5.5,   Method: Compositional matrix adjust.
 Identities = 24/76 (31%), Positives = 36/76 (47%)
 Frame = -1

Query: 179 GSTIFVANLDFKVGWKKLKEVFSIAGTVKRADIKEDKDGKSRGMGTVTFEQAIEAVQAIS 238
           G T++V  +   V    LK  FS  G +   +I+     + R  G VTFE+   A QAI+
Sbjct: 489 GHTVYVHGI--GVTEDILKSAFSNFGNIVNINIE-----RERNNGFVTFEKMESADQAIA 331

Query: 239 MFNGQFLFDRPMHVKM 254
             NG  + +  + V M
Sbjct: 330 NMNGSMISNVQLKVMM 283
>16427
          Length = 1313

 Score = 37.7 bits (86), Expect = 0.011,   Method: Compositional matrix adjust.
 Identities = 22/73 (30%), Positives = 41/73 (56%), Gaps = 1/73 (1%)
 Frame = +1

Query: 182 IFVANLDFKVGWKKLKEVFSIAGTVKRADIKEDKDGK-SRGMGTVTFEQAIEAVQAISMF 240
           +FV  L  ++  K L+  FS  G +  + +  DK  + SRG G VT+E  ++A +A+   
Sbjct: 142 LFVGGLAEEIDEKVLEREFSKFGRITESMVIRDKVRQVSRGFGFVTYENPMDAEEAVKHM 321

Query: 241 NGQFLFDRPMHVK 253
           +G+ +  + +HV+
Sbjct: 322 DGKEILGKKLHVE 360
>03406
          Length = 1292

 Score = 37.4 bits (85), Expect = 0.013,   Method: Compositional matrix adjust.
 Identities = 29/100 (29%), Positives = 52/100 (52%), Gaps = 1/100 (1%)
 Frame = +3

Query: 37  GTGEKKGPNRNRVFISNIPYDMKWQAIKDLMREKVGEVTYVELFKDAE-GKSRGCGVVEF 95
           G  E++  +  ++F+  + ++   + +++   EK GEVT   L  D + GKSRG G V F
Sbjct: 210 GDAEEENEDDRKIFVGGLSWETXSKHLREYF-EKFGEVTSCTLKTDLDSGKSRGFGFVVF 386

Query: 96  KDEEFVKKALETMNKYDLSGRPLNIKEDPDGENARRALQR 135
           K+   V  A+    ++ L GR +    DP   N R+ +++
Sbjct: 387 KEAATV-DAVVKNKEHKLQGRKI----DPKPANPRKGMRK 491
>10194
          Length = 1278

 Score = 37.0 bits (84), Expect = 0.020,   Method: Compositional matrix adjust.
 Identities = 23/78 (29%), Positives = 42/78 (53%), Gaps = 2/78 (2%)
 Frame = -3

Query: 455 IFVRNLPFDLTWQKLKEKFSQCGHVMFAEIKMENGKS--KGCGTVRFESAESAEKACRIM 512
           +FV NLPFD+  + ++  F  CG V    +  +   +  KG   + F+SA+S   A + +
Sbjct: 400 VFVGNLPFDIEEESVRSHFEDCGDVENIRVVRDRKTNLGKGICYILFKSADSVSLALK-L 224

Query: 513 NGIKISGREIDVRLDRNA 530
           N  ++  R+I V+  ++A
Sbjct: 223 NNSELEKRQIRVQRCKDA 170

 Score = 30.4 bits (67), Expect = 1.7,   Method: Compositional matrix adjust.
 Identities = 19/79 (24%), Positives = 42/79 (53%), Gaps = 1/79 (1%)
 Frame = -3

Query: 49  VFISNIPYDMKWQAIKDLMREKVGEVTYVELFKDAEGK-SRGCGVVEFKDEEFVKKALET 107
           VF+ N+P+D++ ++++    E  G+V  + + +D +    +G   + FK  + V  AL+ 
Sbjct: 400 VFVGNLPFDIEEESVRSHF-EDCGDVENIRVVRDRKTNLGKGICYILFKSADSVSLALK- 227

Query: 108 MNKYDLSGRPLNIKEDPDG 126
           +N  +L  R + ++   D 
Sbjct: 226 LNNSELEKRQIRVQRCKDA 170
>26197
          Length = 1365

 Score = 36.6 bits (83), Expect = 0.024,   Method: Compositional matrix adjust.
 Identities = 28/98 (28%), Positives = 50/98 (51%), Gaps = 1/98 (1%)
 Frame = -2

Query: 39   GEKKGPNRNRVFISNIPYDMKWQAIKDLMREKVGEVTYVELFKDAE-GKSRGCGVVEFKD 97
            G ++  +  ++F+  + ++   + +++   EK GEVT   L  D + GKSRG G V FK 
Sbjct: 1322 GREENEDDRKIFVGGLSWETSSKHLREYF-EKFGEVTSCTLKTDLDSGKSRGFGFVVFK- 1149

Query: 98   EEFVKKALETMNKYDLSGRPLNIKEDPDGENARRALQR 135
            E     A+    ++ L GR +    DP   N R+ +++
Sbjct: 1148 EAVTVDAVVKNKEHKLQGRKI----DPKPANPRKGMRK 1047
>25746
          Length = 475

 Score = 36.6 bits (83), Expect = 0.027,   Method: Composition-based stats.
 Identities = 25/83 (30%), Positives = 41/83 (49%), Gaps = 9/83 (10%)
 Frame = +1

Query: 451 KGNQIFVRNLPFDLTWQKLKEKFSQCGHVMF------AEIKM---ENGKSKGCGTVRFES 501
           K   ++V  LP DLT ++ +E  S+ G +MF       ++K+    +G  KG G   +  
Sbjct: 67  KSTHVYVSGLPSDLTDEQFQELMSKYGLIMFDPHTHKPKLKLYRNHDGTLKGDGLCCYIK 246

Query: 502 AESAEKACRIMNGIKISGREIDV 524
            ES + A  I++G  + G  I V
Sbjct: 247 QESVDLALNILDGSDVHGSTISV 315
>11687
          Length = 676

 Score = 36.2 bits (82), Expect = 0.033,   Method: Compositional matrix adjust.
 Identities = 47/217 (21%), Positives = 81/217 (37%), Gaps = 8/217 (3%)
 Frame = +3

Query: 48  RVFISNIPYDMKWQAIKDLMREKVGEVTYVELFKDAE-GKSRGCGVVEF---KDEEFVKK 103
           ++F+  IP +M    ++  M E  G V  + + +D   G+S+GC  V F   K     + 
Sbjct: 153 KMFVGQIPRNMDENELRK-MFEDYGPVHSLNILRDKNTGQSKGCCFVTFFTRKAALDAQN 329

Query: 104 ALETMNKYDLSGRPLNIKE-DPDGENARRALQRTGTSFQGSHASDVGSGLVXXXXXXXXX 162
           AL  +    +   P+ +K  D +  N  R                               
Sbjct: 330 ALHNVKTMPMMHHPVQMKPADSEKRNGER------------------------------- 416

Query: 163 XXXXXEVISNLQAGRLGSTIFVANLDFKVGWKKLKEVFSIAGTVKRADIKEDKDGKSRGM 222
                    N++  +L    FV  L  K+    ++ +F   G++    +  D +G SRG 
Sbjct: 417 ---------NVEERKL----FVGMLSKKLSENDVRMLFESFGSIDDCTVLRDSNGTSRGC 557

Query: 223 GTVTFEQAIEAVQAIS-MFNGQFL--FDRPMHVKMDD 256
             +TF     A+ +I  M + Q +     P+ VKM D
Sbjct: 558 AFITFASRQCAMNSIKGMHHSQTMEGCSSPLVVKMAD 668
>24983
          Length = 433

 Score = 35.4 bits (80), Expect = 0.060,   Method: Composition-based stats.
 Identities = 25/76 (32%), Positives = 39/76 (51%), Gaps = 2/76 (2%)
 Frame = -2

Query: 453 NQIFVRNLPFDLTWQKLKEKFSQCGHVMFAEI--KMENGKSKGCGTVRFESAESAEKACR 510
           +Q  +  LP+  T   L+E F + G +  A +    + GKS+G G V       A++AC+
Sbjct: 315 HQDLLGGLPYHTTDHSLREYFDKFGDIDEAVVITDRQTGKSRGYGFVTMADRTGADRACK 136

Query: 511 IMNGIKISGREIDVRL 526
             N I I GR+ +V L
Sbjct: 135 DPNPI-IDGRKANVNL 91
>02343
          Length = 1715

 Score = 34.3 bits (77), Expect = 0.12,   Method: Compositional matrix adjust.
 Identities = 23/79 (29%), Positives = 35/79 (44%), Gaps = 2/79 (2%)
 Frame = -2

Query: 180  STIFVANLDFKVGWKKLKEVFSIAGTVKRADIKEDKDGKSRGMGTVTFEQAIEAVQAISM 239
            + +++ANL      K L+ +F   GTV    I    DG SR +G    E   +    I+ 
Sbjct: 1027 TNLYIANLPLHFTEKHLEGLFKDYGTVISTRILRKPDGISRCVGFARMESRDKCDTVINT 848

Query: 240  FNGQFL--FDRPMHVKMDD 256
            FN + +     P+ VK  D
Sbjct: 847  FNNKMISGCSEPLLVKFAD 791
>17681
          Length = 964

 Score = 33.5 bits (75), Expect = 0.20,   Method: Compositional matrix adjust.
 Identities = 25/75 (33%), Positives = 35/75 (46%), Gaps = 2/75 (2%)
 Frame = +2

Query: 450 SKGNQIFVRNLPFDLTWQKLKEKFSQCGHVMFAEI--KMENGKSKGCGTVRFESAESAEK 507
           S  + IFV +L  ++  + L+E F+  G +    I    +  KSKG   V F     AE 
Sbjct: 23  SSHHHIFVGDLSPEIETETLREAFAPFGEISNCRIVRDPQTMKSKGYAFVSFVKKAEAEN 202

Query: 508 ACRIMNGIKISGREI 522
           A + MNG  I  R I
Sbjct: 203 AIQAMNGQWIGSRSI 247
>19733
          Length = 723

 Score = 32.3 bits (72), Expect = 0.46,   Method: Compositional matrix adjust.
 Identities = 57/225 (25%), Positives = 83/225 (36%), Gaps = 46/225 (20%)
 Frame = +3

Query: 72  GEVTYVELFKD-AEGKSRGCGVVEFKDEEFVKKALETMNKYD--------LSGRPLNI-- 120
           GE+ YV L  D   G+SRG   V+FK+++   + L   N  D        + GRPL +  
Sbjct: 3   GELAYVRLVIDKVTGQSRGTAFVQFKEKDAADQCL--ANXQDTTRGGGLRVQGRPLYVVA 176

Query: 121 ----------------KEDPDGEN---ARRALQRTGT-SFQGSHASDVGSGLVXXXXXXX 160
                           KE  D  N   AR  L R GT + +G    D+   +        
Sbjct: 177 AVSRTQAQTQKEADKSKEQKDNRNLFLAREGLIRAGTQAAEGMSQEDINKRM-------- 332

Query: 161 XXXXXXXEVISNLQAGRLGSTIFVANLDFKVGWKKLKEVF-------SIAGTVKR----- 208
                  E + N+      + + V NL   V  K+LK V        ++  T  R     
Sbjct: 333 KVEMVKREKLKNINIFVSSTRLCVHNLLPSVDEKQLKTVVRKIVDDSTMKITECRVMRDL 512

Query: 209 ADIKEDKDGKSRGMGTVTFEQAIEAVQAISMFNGQFLF---DRPM 250
           A  K+    KS G   V F     A++A+   N   +F    RP+
Sbjct: 513 ARTKQSGQSKSLGYAFVNFSTHEHALKALRGLNNSTMFGDSRRPI 647
>12215
          Length = 539

 Score = 32.0 bits (71), Expect = 0.59,   Method: Compositional matrix adjust.
 Identities = 20/79 (25%), Positives = 37/79 (46%)
 Frame = +3

Query: 42  KGPNRNRVFISNIPYDMKWQAIKDLMREKVGEVTYVELFKDAEGKSRGCGVVEFKDEEFV 101
           + PN N++ I N+P       +KD++ + + EV      K  +G S G   V F   E  
Sbjct: 198 RKPN-NKIQIKNLPPSASCDTVKDIVNDVIPEVAQ----KFEQGSSEGVFYVTFDTVENA 362

Query: 102 KKALETMNKYDLSGRPLNI 120
           ++A+  +N Y +    + +
Sbjct: 363 QQAVTLLNDYKVEDNEIQV 419
>32386
          Length = 674

 Score = 31.2 bits (69), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 27/105 (25%), Positives = 53/105 (50%), Gaps = 3/105 (2%)
 Frame = +1

Query: 48  RVFISNIPYDMKWQAIKDLMREKVGEVTYVELFKDAEGK-SRGCGVVEFKDEEFVKKALE 106
           ++FI  + Y+    +++    E  GE+    + +D+  K SRG G + +KD E + +A +
Sbjct: 304 KLFIGGLSYETDEDSLRSHF-ETWGEIVDCIVMRDSNSKRSRGFGFITYKDAESIDQA-Q 477

Query: 107 TMNKYDLSGRPLNIKED-PDGENARRALQRTGTS-FQGSHASDVG 149
               + + GR ++ K   P  E+ R  +Q++    F GS +  +G
Sbjct: 478 ANRPHKIDGREVDTKRAMPREESGRSEVQQSVKKMFVGSLSCKLG 612
>03000
          Length = 778

 Score = 30.4 bits (67), Expect = 1.9,   Method: Compositional matrix adjust.
 Identities = 23/91 (25%), Positives = 47/91 (51%), Gaps = 2/91 (2%)
 Frame = +3

Query: 48  RVFISNIPYDMKWQAIKDLMREKVGEVTYVELFKDAEGK-SRGCGVVEFKDEEFVKKALE 106
           ++FI  + Y+    +++    E  GE+    + +D+  K SRG G + +KD E + +A +
Sbjct: 90  KLFIGGLSYETDEDSLRSHF-ETWGEIVDCIVMRDSNSKRSRGFGFITYKDAESIDQA-Q 263

Query: 107 TMNKYDLSGRPLNIKED-PDGENARRALQRT 136
               + + GR ++ K   P  E+ R  +Q++
Sbjct: 264 ANRPHKIDGREVDTKRAMPREESGRSEVQQS 356
>11019
          Length = 552

 Score = 30.4 bits (67), Expect = 2.1,   Method: Compositional matrix adjust.
 Identities = 43/187 (22%), Positives = 62/187 (33%), Gaps = 7/187 (3%)
 Frame = -1

Query: 58  MKWQAIKDLMR---EKVGEVTYVELFKDAEGK-SRGCGVVEFKDEEFVKKALETMNKYDL 113
           + WQ   + +R   EK GE+    + KD   K SRG G V +KD   V   L        
Sbjct: 543 LSWQTTTETLRSYFEKFGEIKESMVMKDPTSKRSRGFGFVTYKDPSNVDNVLA------- 385

Query: 114 SGRPLNIKEDPDGENARRALQRTGTSFQGSHASDVGSGLVXXXXXXXXXXXXXXEVISNL 173
                         N    +     +F           L+              +  SN 
Sbjct: 384 --------------NGPHCIDSKTLNFSNMTTFYSNQDLLPYPPQVDPKVAFPRK--SNP 253

Query: 174 QAGRLGSTIFVANLDFKVGWKKLKEVFSIAGTVKRADIKEDK-DGKSRGMGTVTF--EQA 230
           +       IFV  L      + +K  F   GT++ A +  DK   + RG   VTF  E  
Sbjct: 252 RMVTKTKKIFVGGLSSSTTVEDIKNYFKAYGTIEEATLMFDKVTSRHRGFAFVTFDNEST 73

Query: 231 IEAVQAI 237
           ++ V  I
Sbjct: 72  VDKVCEI 52
>25950
          Length = 417

 Score = 30.0 bits (66), Expect = 2.3,   Method: Compositional matrix adjust.
 Identities = 18/68 (26%), Positives = 37/68 (54%), Gaps = 5/68 (7%)
 Frame = -2

Query: 181 TIFVANLDFKVGWKKLKEVFSIAGTVKRADIKEDK-DGKSRGMGTVTF--EQAIEAVQAI 237
           +++V N+D+    ++L+  F   GT+ R  I  +K DG  +G   + F  ++ +E   A+
Sbjct: 278 SVYVGNVDYGASAEELEAHFHGCGTINRVTILCNKADGHPKGFAYIEFGSKEYVETALAM 99

Query: 238 --SMFNGQ 243
             ++F G+
Sbjct: 98  NETLFRGR 75
>33516
          Length = 449

 Score = 29.6 bits (65), Expect = 3.4,   Method: Compositional matrix adjust.
 Identities = 17/61 (27%), Positives = 30/61 (49%), Gaps = 1/61 (1%)
 Frame = +1

Query: 48  RVFISNIPYDMKWQAIKDLMREKVGEVT-YVELFKDAEGKSRGCGVVEFKDEEFVKKALE 106
           ++F+  + +D    +++    +  GE+T  + +     GKSRG G V FKD   V   L 
Sbjct: 157 KIFVGGLSWDTDQDSLQGYFSQ-FGEITDCIVMMNQQTGKSRGFGFVSFKDPSTVDVILS 333

Query: 107 T 107
           +
Sbjct: 334 S 336

 Score = 29.3 bits (64), Expect = 4.6,   Method: Compositional matrix adjust.
 Identities = 18/55 (32%), Positives = 28/55 (50%), Gaps = 2/55 (3%)
 Frame = +1

Query: 454 QIFVRNLPFDLTWQKLKEKFSQCGHVMFAEIKM--ENGKSKGCGTVRFESAESAE 506
           +IFV  L +D     L+  FSQ G +    + M  + GKS+G G V F+   + +
Sbjct: 157 KIFVGGLSWDTDQDSLQGYFSQFGEITDCIVMMNQQTGKSRGFGFVSFKDPSTVD 321
>07622
          Length = 2072

 Score = 29.3 bits (64), Expect = 4.3,   Method: Compositional matrix adjust.
 Identities = 16/33 (48%), Positives = 21/33 (63%), Gaps = 3/33 (9%)
 Frame = +3

Query: 82   DAEGKSR---GCGVVEFKDEEFVKKALETMNKY 111
            D EGK+R   GCGVV  KD     +AL+ +N+Y
Sbjct: 1356 DKEGKARKVNGCGVVVVKDYGKESQALDVLNEY 1454
>03903
          Length = 983

 Score = 29.3 bits (64), Expect = 4.6,   Method: Compositional matrix adjust.
 Identities = 20/85 (23%), Positives = 40/85 (47%), Gaps = 5/85 (5%)
 Frame = -1

Query: 41  KKGPNRNRVFISNIP-----YDMKWQAIKDLMREKVGEVTYVELFKDAEGKSRGCGVVEF 95
           K+G    R++I N+       D+ W   + +  +K  E +  ++    EG+ +G   V  
Sbjct: 476 KEGEPSRRLYIKNLSKQVTEEDLHWVFGRYVNWDKEEEKSIFDIRLMKEGRMKGQAFVTL 297

Query: 96  KDEEFVKKALETMNKYDLSGRPLNI 120
             EE  +KA++  N +   G+P+ +
Sbjct: 296 GTEEQARKAVKDTNAFVFKGKPIAV 222
>19980
          Length = 450

 Score = 28.9 bits (63), Expect = 6.1,   Method: Composition-based stats.
 Identities = 17/47 (36%), Positives = 23/47 (48%)
 Frame = -2

Query: 194 KKLKEVFSIAGTVKRADIKEDKDGKSRGMGTVTFEQAIEAVQAISMF 240
           K L+++FS  GT+    +K   DGK R    V F    EA  A + F
Sbjct: 143 KMLRDLFSKKGTITDCSLKHTADGKFRRFAFVGFSCEEEAKTAQAYF 3
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|65301477|ref|NP_780728.3| potassium channel
tetramerisation domain containing 8 [Mus musculus]
         (476 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

12256                                                                  71   1e-12
21310                                                                  59   4e-09
33196                                                                  39   0.004
18577                                                                  36   0.029
31022                                                                  28   8.8  
00590                                                                  28   9.1  
>12256
          Length = 1703

 Score = 70.9 bits (172), Expect = 1e-12,   Method: Compositional matrix adjust.
 Identities = 41/102 (40%), Positives = 54/102 (52%), Gaps = 3/102 (2%)
 Frame = +2

Query: 46  VELNVGGQVYVTKHSTLLSVPDSTLASMFXXXXXXXXXXXXXDLPRDSRARFFIDRDGFL 105
           ++L+VGG V+ T   TL    DS LA+MF              L ++     FIDRDG  
Sbjct: 458 IKLDVGGHVFTTSQLTLTREADSMLAAMFSGRH---------GLTKEEDGSVFIDRDGTH 610

Query: 106 FRYVLDYLRDKQL---ALPEHFPEKERLLREAEFFQLTDLVK 144
           FRY+L+YLRD  L   ALP H    + L  EA +FQL  L++
Sbjct: 611 FRYILNYLRDGGLSADALPRHKQTLKELRNEAVYFQLHGLIQ 736
>21310
          Length = 865

 Score = 58.9 bits (141), Expect = 4e-09,   Method: Compositional matrix adjust.
 Identities = 33/79 (41%), Positives = 42/79 (53%), Gaps = 3/79 (3%)
 Frame = +2

Query: 46  VELNVGGQVYVTKHSTLLSVPDSTLASMFXXXXXXXXXXXXXDLPRDSRARFFIDRDGFL 105
           ++L+VGG V+ T   TL    DS LA+MF              L ++     FIDRDG  
Sbjct: 539 IKLDVGGHVFTTSQLTLTREADSMLAAMFSGRH---------GLKKEDDGTIFIDRDGTH 691

Query: 106 FRYVLDYLRDKQL---ALP 121
           FRY+L+YLRD  L   ALP
Sbjct: 692 FRYILNYLRDGGLSSDALP 748
>33196
          Length = 373

 Score = 39.3 bits (90), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 24/79 (30%), Positives = 39/79 (49%), Gaps = 1/79 (1%)
 Frame = -3

Query: 46  VELNVGGQVYVTKHSTLLSVPDSTLASMFXXXXXXXXXXXXXDLPRDSRAR-FFIDRDGF 104
           +++NV G+ + T  +TL   PD+ L S               +   D  ++ +F DRD  
Sbjct: 353 LKINVSGRKFETWRTTLEKYPDTLLGS------------NEKEFFYDEESKEYFFDRDPD 210

Query: 105 LFRYVLDYLRDKQLALPEH 123
           LFR++L+Y R   L  P+H
Sbjct: 209 LFRHILNYYRTGSLHYPKH 153
>18577
          Length = 459

 Score = 36.2 bits (82), Expect = 0.029,   Method: Compositional matrix adjust.
 Identities = 19/55 (34%), Positives = 33/55 (60%)
 Frame = -1

Query: 106 FRYVLDYLRDKQLALPEHFPEKERLLREAEFFQLTDLVKLLSPKVTKQNSLNDEC 160
           F  +L++LRD  L LPE+  E   L +EA+++ +TDL  L+   +  ++ L+  C
Sbjct: 453 FGSILNFLRDGTLPLPENRRELLELQQEAKYYLVTDLCTLIDQALKMRDELDPIC 289
>31022
          Length = 815

 Score = 28.1 bits (61), Expect = 8.8,   Method: Compositional matrix adjust.
 Identities = 13/31 (41%), Positives = 16/31 (51%)
 Frame = +1

Query: 372 PQDNPANTQQAAAHQPNTLTLDRPSRKAPVQ 402
           P +N   T +   +QP TL  DR    APVQ
Sbjct: 307 PAENGPKTVKVFINQPTTLDFDRADSMAPVQ 399
>00590
          Length = 2486

 Score = 28.1 bits (61), Expect = 9.1,   Method: Compositional matrix adjust.
 Identities = 23/71 (32%), Positives = 33/71 (46%), Gaps = 3/71 (4%)
 Frame = +2

Query: 390  LTLDRPSRKAPVQWMPPPDKRRNSELF---QSLISKSRETNLSKKKVCEKLSVEEEMKKC 446
            +TL  P R+ P+Q  PP  KR++SE      SL    R  N S + V   L     +   
Sbjct: 989  VTLTEP-RQPPLQVEPPAKKRQHSEALL*HNSLCFCCRYLNSSIRSVAYNLVTRNPLVVN 1165

Query: 447  IQDFKKIHIPD 457
              DF +I++ D
Sbjct: 1166 KSDFFQIYVYD 1198
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6753810|ref|NP_034304.1| fatty acid binding protein
3, muscle and heart [Mus musculus]
         (133 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

07957                                                                  68   1e-12
31753                                                                  34   0.016
03139                                                                  30   0.29 
15183                                                                  28   0.95 
00971                                                                  27   1.8  
>07957
          Length = 883

 Score = 67.8 bits (164), Expect = 1e-12,   Method: Compositional matrix adjust.
 Identities = 44/125 (35%), Positives = 63/125 (50%)
 Frame = +1

Query: 1   MADAFVGTWKLVDSKNFDDYMKSLGVGFATRQVASMTKPTTIIEKNGDTITIKTQSTFKN 60
           MAD  +G W+ V  +N D     +GV  A RQ A   K    IEK+G    + T +  K+
Sbjct: 259 MADGLIGKWQSVSYENMDPLWDVMGVPDAMRQFARDKKTELTIEKDGGQWKLTTVAGDKS 438

Query: 61  TEINFQLGIEFDEVTADDRKVKSLVTLDGGKLIHVQKWNGQETTLTRELVDGKLILTLTH 120
             I F +G E D +T     VK+++T +GG+L+  QK    E  + R L DGKL   +T 
Sbjct: 439 RVIVFPVGQEVDTITLMGEPVKAILTEEGGQLVERQKAGVGEIIIQRSLQDGKLKTNMTL 618

Query: 121 GSVVS 125
             V +
Sbjct: 619 KGVTA 633
>31753
          Length = 374

 Score = 34.3 bits (77), Expect = 0.016,   Method: Compositional matrix adjust.
 Identities = 20/65 (30%), Positives = 33/65 (50%), Gaps = 5/65 (7%)
 Frame = -3

Query: 4   AFVGTWKLVDSKNFDDYMKSLGVG--FATRQVASMTKPTTIIEK---NGDTITIKTQSTF 58
           A  G WKLV   NF+ Y+ ++GV   F  + +  +T    I++    +GD I+I T +  
Sbjct: 222 ALNGKWKLVSVDNFESYLDAVGVQGEFRDKALKLLTPENNILQDIAIDGDAISITTTTPI 43

Query: 59  KNTEI 63
              E+
Sbjct: 42  APIEV 28
>03139
          Length = 1372

 Score = 30.0 bits (66), Expect = 0.29,   Method: Compositional matrix adjust.
 Identities = 18/52 (34%), Positives = 33/52 (63%), Gaps = 1/52 (1%)
 Frame = -3

Query: 81   VKSLVTLDGGKLIHVQKWNGQETTLTRELVDG-KLILTLTHGSVVSTRTYEK 131
            +K++ T++G  L  V+  +G  +T+    V+G ++I+T+  G V STR Y+K
Sbjct: 1370 IKTVFTIEGDTL--VENVSGPLSTVIVRAVEGSQMIMTMKSGDVTSTRKYDK 1221
>15183
          Length = 1201

 Score = 28.5 bits (62), Expect = 0.95,   Method: Compositional matrix adjust.
 Identities = 23/100 (23%), Positives = 43/100 (43%), Gaps = 20/100 (20%)
 Frame = +1

Query: 23  SLGVGFATRQVASMTKPTTII-------EKNGDT------ITIKTQSTFKNTEINFQLGI 69
           ++G+  + +Q   + KP+  +       E    T      + I+   TF+   ++   GI
Sbjct: 772 TVGLRCSCKQHCPLEKPSGALSDMKCSQEHKAQTMDGERVVLIEDGKTFR---MSGSAGI 942

Query: 70  EFDEVTADDRKVKSLVTLD-------GGKLIHVQKWNGQE 102
           +F      D   + L++LD          +IH++KW GQE
Sbjct: 943 QFSAKVDSDGTCRCLLSLDFXCYFCGWXTIIHLKKWKGQE 1062
>00971
          Length = 3216

 Score = 27.3 bits (59), Expect = 1.8,   Method: Compositional matrix adjust.
 Identities = 11/35 (31%), Positives = 20/35 (57%)
 Frame = +2

Query: 39   PTTIIEKNGDTITIKTQSTFKNTEINFQLGIEFDE 73
            PTT++E  G +     Q  +  T+++  +GI +DE
Sbjct: 2813 PTTVVEMRGQSTPTIWQQYYMFTDLHLCVGIIYDE 2917
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|29789076|ref|NP_056627.1| regulator of G-protein
signaling 6 [Mus musculus]
         (472 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

28964                                                                  70   2e-12
17291                                                                  47   1e-05
11322                                                                  29   3.7  
>28964
          Length = 433

 Score = 69.7 bits (169), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 36/95 (37%), Positives = 59/95 (62%), Gaps = 1/95 (1%)
 Frame = +1

Query: 355 ESEFSSENLRFWLSVQDLKKQPLQDVAKR-VEEIWQEFLAPGAPSAINLDSHSYEITSQN 413
           E EFS EN+ FW +V+  K    +D+ +R   EI+   L P A   +N+DS + ++T Q 
Sbjct: 70  EKEFSEENIVFWTAVESYKHIIDEDLRRRRAGEIYSSHLGPQASDPVNVDSTARQLTEQY 249

Query: 414 VKDGGRYTFEDAQEHIYKLMKSDSYARFLRSNAYQ 448
           + +     F+ AQ  I++LM++DSY+RFL+S+ Y+
Sbjct: 250 LDNPTPNMFDVAQHQIFQLMRTDSYSRFLKSDLYK 354
>17291
          Length = 479

 Score = 47.4 bits (111), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 21/30 (70%), Positives = 25/30 (83%)
 Frame = -2

Query: 419 RYTFEDAQEHIYKLMKSDSYARFLRSNAYQ 448
           R+TF  AQEHI+ LMK DSYARFLRS+ Y+
Sbjct: 475 RFTFLAAQEHIFLLMKKDSYARFLRSDHYK 386
>11322
          Length = 1521

 Score = 29.3 bits (64), Expect = 3.7,   Method: Compositional matrix adjust.
 Identities = 18/44 (40%), Positives = 25/44 (56%), Gaps = 1/44 (2%)
 Frame = -3

Query: 360 SENLRF-WLSVQDLKKQPLQDVAKRVEEIWQEFLAPGAPSAINL 402
           + NL F WL  +DL+ +PL  VAKR    W  FL   +  ++NL
Sbjct: 520 NSNLLFRWLLGEDLRDRPLLSVAKR----WSLFLKTVSQXSVNL 401
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6753964|ref|NP_034397.1| ganglioside-induced
differentiation-associated-protein 1 [Mus musculus]
         (358 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

18203                                                                  69   2e-12
18621                                                                  42   4e-04
32130                                                                  42   4e-04
12484                                                                  40   0.001
20426                                                                  37   0.016
28643                                                                  35   0.041
15762                                                                  35   0.059
03831                                                                  32   0.52 
20497                                                                  30   1.6  
>18203
          Length = 435

 Score = 69.3 bits (168), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 45/114 (39%), Positives = 67/114 (58%), Gaps = 3/114 (2%)
 Frame = +2

Query: 21  DKEVHLILYHWTHSFSSQKVRLVIAEKALKCEEHDVSLPLSEHNEPWFMRLNSAG-EVPV 79
           + E  + LY++  SFSSQKV L   EK ++ +   VSL   +H EPW+++LN  G  VPV
Sbjct: 95  ENEKEITLYYFPTSFSSQKVLLAAYEKGVQFKPRLVSLFHGQHMEPWYVKLNPEGTHVPV 274

Query: 80  LVHGENIICEATQIIDYLE--QTFLDERTPRLMPDEGSMYYPRVQHYRELLDSL 131
           LVHG  I+    +IIDY++  +T +D    RL+PD  +     +   RE L++L
Sbjct: 275 LVHGALILNNPEEIIDYIDSLETGMDV---RLVPDIQTSEGQSMAAIREQLNAL 427
>18621
          Length = 515

 Score = 42.0 bits (97), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 22/63 (34%), Positives = 37/63 (58%), Gaps = 1/63 (1%)
 Frame = -2

Query: 40  VRLVIAEKALKCEEHDVSLPLSEHNEP-WFMRLNSAGEVPVLVHGENIICEATQIIDYLE 98
            RL+++ K +K +  +V L    +N+P WF  +N  GEVPV++H    + E+    +YLE
Sbjct: 514 ARLILSAKKVKYDRVNVDL----NNKPDWFFDVNFYGEVPVIIHNGKNVYESLICSEYLE 347

Query: 99  QTF 101
           + F
Sbjct: 346 EAF 338
>32130
          Length = 459

 Score = 42.0 bits (97), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 29/90 (32%), Positives = 47/90 (52%), Gaps = 2/90 (2%)
 Frame = -3

Query: 27  ILYHWTHSFSSQKVRLVIAEKALKCEEHDVSL--PLSEHNEPWFMRLNSAGEVPVLVHGE 84
           +LY +  S +S +VR+ +A K +  +   V L     E N+  +  +N  G+VP LV   
Sbjct: 352 LLYSYFRSTASWRVRIALAMKGVDYDYAPVHLVKDGGEQNKEEYKSVNPMGQVPTLVIDG 173

Query: 85  NIICEATQIIDYLEQTFLDERTPRLMPDEG 114
             + ++  II+YLE+T   + TP L  D G
Sbjct: 172 LTLTQSMPIIEYLEET--RQGTPILPKDAG 89
>12484
          Length = 912

 Score = 40.0 bits (92), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 19/52 (36%), Positives = 30/52 (57%), Gaps = 1/52 (1%)
 Frame = +2

Query: 216 LDQVETELQRR-NEETPEEGNQPWLCGESFTLADVSLAVTLHRLKFLGFARR 266
           LD +  +L++R   +  ++G   WL G+ FT AD++L+V L R   LG   R
Sbjct: 74  LDSLFQDLEKRMGADYTDKGGDQWLFGKQFTAADIALSVLLQRFTLLGLDTR 229
>20426
          Length = 398

 Score = 36.6 bits (83), Expect = 0.016,   Method: Compositional matrix adjust.
 Identities = 19/52 (36%), Positives = 33/52 (63%), Gaps = 2/52 (3%)
 Frame = -2

Query: 41  RLVIAEKALKCEEHDVSLPLSEHNEP-WFMRLNSAGEVPVLVH-GENIICEA 90
           RL+++ K +K +  +V L    +N+P WF  +N  GEVPV++H G+N++   
Sbjct: 394 RLILSAKKVKYDRVNVDL----NNKPDWFFDVNFYGEVPVIIHNGKNVVSGG 251
>28643
          Length = 748

 Score = 35.0 bits (79), Expect = 0.041,   Method: Compositional matrix adjust.
 Identities = 17/55 (30%), Positives = 30/55 (54%)
 Frame = +2

Query: 61  SEHNEPWFMRLNSAGEVPVLVHGENIICEATQIIDYLEQTFLDERTPRLMPDEGS 115
            EH     ++LN  G++P    G+ ++ E+  I DYLE  F ++   RL+P++  
Sbjct: 80  KEHKGAEVLKLNQRGQLPTFKDGDLVVNESGAICDYLEFKFPEK---RLLPEDAG 235
>15762
          Length = 593

 Score = 34.7 bits (78), Expect = 0.059,   Method: Compositional matrix adjust.
 Identities = 23/76 (30%), Positives = 36/76 (47%), Gaps = 1/76 (1%)
 Frame = -1

Query: 217 DQVETELQRRNEETPEEGNQPWLCGESFTLADVSLAVTLHRLKFLGFA-RRNWGHGKRPN 275
           ++   ELQ   E   ++G   ++ G+ FT+ADV      +    + F  R     GK P 
Sbjct: 587 EEARKELQLWEEYLSKQGAGTYVVGKKFTMADV------YVFPVIAFGVRGQLDLGKFPA 426

Query: 276 LETYYERVLKRKTFNK 291
           L+ YYE V +R +  K
Sbjct: 425 LKAYYEMVKERDSIKK 378
>03831
          Length = 1143

 Score = 31.6 bits (70), Expect = 0.52,   Method: Compositional matrix adjust.
 Identities = 21/62 (33%), Positives = 30/62 (48%)
 Frame = +3

Query: 84  ENIICEATQIIDYLEQTFLDERTPRLMPDEGSMYYPRVQHYRELLDSLPMDAYTHGCILH 143
           +N   +  +I   +E T   E  P+ +PDE S+Y PR+ H  +  D    D Y  G  LH
Sbjct: 471 DNXENQEAEIAAVVEATNGTEPEPQSLPDESSLYAPRLCHLCKWAD---FDGY--GFNLH 635

Query: 144 PE 145
            E
Sbjct: 636 AE 641
>20497
          Length = 680

 Score = 30.0 bits (66), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 18/70 (25%), Positives = 35/70 (50%)
 Frame = -3

Query: 72  NSAGEVPVLVHGENIICEATQIIDYLEQTFLDERTPRLMPDEGSMYYPRVQHYRELLDSL 131
           N  G+VPV+    +++CE+  + +YL+  + D   PRL     + +      YR+  D +
Sbjct: 480 NPNGQVPVVEKDGSVVCESLIVAEYLDSAYPD---PRL-----AFHLIPANPYRKARDDM 325

Query: 132 PMDAYTHGCI 141
            ++ Y +  I
Sbjct: 324 IINDYANKFI 295
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|84875537|ref|NP_035010.3| nucleolin [Mus musculus]
         (707 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

17775                                                                  70   2e-12
05987                                                                  62   9e-10
25691                                                                  62   9e-10
00302                                                                  54   2e-07
39789                                                                  51   2e-06
28652                                                                  47   2e-05
19868                                                                  47   3e-05
02343                                                                  47   3e-05
02415                                                                  47   4e-05
08816                                                                  45   8e-05
28455                                                                  44   3e-04
25950                                                                  43   5e-04
12506                                                                  42   8e-04
03059                                                                  42   0.001
31618                                                                  41   0.002
20169                                                                  41   0.002
16016                                                                  40   0.002
33516                                                                  40   0.003
30672                                                                  40   0.003
31265                                                                  40   0.005
11687                                                                  39   0.006
26197                                                                  39   0.010
13822                                                                  39   0.011
03903                                                                  38   0.011
03406                                                                  38   0.013
31938                                                                  38   0.013
24983                                                                  37   0.021
17681                                                                  37   0.028
23720                                                                  37   0.031
04988                                                                  37   0.033
32386                                                                  37   0.035
05273                                                                  36   0.041
11126                                                                  36   0.042
03856                                                                  32   0.062
03000                                                                  35   0.090
08958                                                                  34   0.16 
12350                                                                  34   0.17 
11108                                                                  34   0.18 
12096                                                                  34   0.20 
11579                                                                  33   0.49 
11019                                                                  33   0.54 
31310                                                                  32   0.95 
16427                                                                  32   1.1  
00781                                                                  32   1.2  
01278                                                                  31   1.7  
02347                                                                  31   1.7  
02809                                                                  30   2.6  
11102                                                                  30   2.9  
29364                                                                  30   3.1  
>17775
          Length = 1282

 Score = 70.5 bits (171), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 92/358 (25%), Positives = 154/358 (43%), Gaps = 46/358 (12%)
 Frame = -2

Query: 305  PTTPF-NLFIGNLNPNKSVNELKFAISELFAKNDLA--VVDVRTG----TNRKFGY--VD 355
            P+ P  +L++G+L+P+  V E     + LF K   A  V+ +R      T R  GY  V+
Sbjct: 1209 PSYPMASLYVGDLHPD--VTE-----AMLFEKFSTAGPVLSIRVCRDMITRRSLGYAYVN 1051

Query: 356  FESAEDLEKALELTGLK-VFGNEIKLEKPKGRDSKKVRAARTLLAKNLSFNITEDELKEV 414
            F+   D E+AL+      V G  I++   +   S +      +  KNL   I    L + 
Sbjct: 1050 FQQPADAERALDTMNFDTVKGRPIRIMWSQRDPSVRKSGVGNVFIKNLDKTIDNKALYDT 871

Query: 415  FE---DAMEIRLVSQDGKSKGIAYIEFKSEADAEKNLEEKQGAEIDGRSVSLYYTGEKGQ 471
            F    + +  ++   +  SKG  ++ F++E  A + +++  G  ++G+ V   Y G    
Sbjct: 870  FSAFGNILSCKIACDEQGSKGYGFVHFETEEAARQAIDKVNGMLLNGKKV---YVGRFIP 700

Query: 472  RQERTGKTSTWSGESKTLVLSN------------LSYSATKETLEEVFEKATFIKVPQNP 519
            R+ER             + + N            L + A ++ L             +  
Sbjct: 699  RKERIMMMGDKLKRFNNVYVKNFC*GTG*RPAA*LVWQARQDHLXX--------GACRGE 544

Query: 520  HGKPKGYAFIEFASFEDAKEALNSCNKMEIEGRTI-------RLELQGS-NSRSQPSK-- 569
             GK +G+ F+ F   E A++A++  N  E+ GR I       R E Q     R +  K  
Sbjct: 543  DGKSRGFGFVSFEEPEGAEKAVDEINGTEVSGRIIYCGRAQKRAERQAELKERFEKIKLE 364

Query: 570  --------TLFVKGLSEDTTEETLKESFE--GSV-RARIVTDRETGSSKGFGFVDFNS 616
                     L+VK L +   +E L++ F   G++  A+I+T  E G SKGFGFV F+S
Sbjct: 363  RINRYQGVNLYVKNLDDSIDDERLRKEFSNFGTITSAKIMT--EGGRSKGFGFVCFSS 196

 Score = 49.3 bits (116), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 41/143 (28%), Positives = 66/143 (46%), Gaps = 14/143 (9%)
 Frame = -2

Query: 426 QDGKSKGIAYIEFKSEADAEKNLEEKQGAEIDGRSVSLYYTGEKGQRQERTG-------- 477
           +DGKS+G  ++ F+    AEK ++E  G E+ GR +   Y G   +R ER          
Sbjct: 546 EDGKSRGFGFVSFEEPEGAEKAVDEINGTEVSGRII---YCGRAQKRAERQAELKERFEK 376

Query: 478 ----KTSTWSGESKTLVLSNLSYSATKETLEEVFEKATFIKVPQ--NPHGKPKGYAFIEF 531
               + + + G +  L + NL  S   E L + F     I   +     G+ KG+ F+ F
Sbjct: 375 IKLERINRYQGVN--LYVKNLDDSIDDERLRKEFSNFGTITSAKIMTEGGRSKGFGFVCF 202

Query: 532 ASFEDAKEALNSCNKMEIEGRTI 554
           +S E+A +A+      E+ GR I
Sbjct: 201 SSPEEATKAVT-----EMNGRII 148
>05987
          Length = 1726

 Score = 62.0 bits (149), Expect = 9e-10,   Method: Compositional matrix adjust.
 Identities = 46/170 (27%), Positives = 78/170 (45%), Gaps = 7/170 (4%)
 Frame = -2

Query: 392  RAARTLLAKNLSFNITEDELKEVFEDAMEIRLV------SQDGKSKGIAYIEFKSEADAE 445
            R   TL  KNL   ++  ++K + +D  E+RL        +  K  G AY+EF SEA A+
Sbjct: 1179 RDKCTLFVKNLPPTVSVTDIKSLSKDIKEVRLRIAVRAKQRQKKKMGFAYVEFASEALAD 1000

Query: 446  KNLEEKQGAEIDGRSVSLYYTGEKGQRQERTGKTSTWSGESKTLVLSNLSYSATKETLEE 505
            KN ++ QG ++    + + Y G+K        +      +   L ++       +  L +
Sbjct: 999  KNYKQLQGTKLKDWDLVVDYVGQKSAYLANKPRKEFADPDPLRLYITGFGSETKEADLFK 820

Query: 506  VFEKATFIKVPQN-PHGKPKGYAFIEFASFEDAKEALNSCNKMEIEGRTI 554
            +F KA  I +P+     KP GYAF  F + E  K A +     +++G  +
Sbjct: 819  LFPKAQEIVIPKRKKDNKPVGYAFAVFVTDEQCKTAFHKNQGAKLQGHNL 670
>25691
          Length = 768

 Score = 62.0 bits (149), Expect = 9e-10,   Method: Compositional matrix adjust.
 Identities = 31/100 (31%), Positives = 56/100 (56%), Gaps = 3/100 (3%)
 Frame = -2

Query: 519 PHGKPKGYAFIEFASFEDAKEALNSCNKMEIEGRTIRLELQGSNSRSQPSKTLFVKGLSE 578
           P G+  GY F+ +   EDA +A+++ N + ++ +TI++ L   +  S     L++ GL +
Sbjct: 410 PTGQSLGYGFVNYKRQEDADKAIHTLNGLRLQNKTIKVSLARPSCESIKGANLYISGLPK 231

Query: 579 DTTEETLKESFEGS---VRARIVTDRETGSSKGFGFVDFN 615
             T+  L+  F      + +RI+ D+ TG SKG GF+ F+
Sbjct: 230 SLTQLDLENLFTDCGNIITSRILYDQTTGLSKGVGFIRFD 111
>00302
          Length = 927

 Score = 53.9 bits (128), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 29/92 (31%), Positives = 48/92 (52%), Gaps = 4/92 (4%)
 Frame = -1

Query: 486 SKTLVLSNLSYSATKETLEEVFEKATFIK----VPQNPHGKPKGYAFIEFASFEDAKEAL 541
           ++ L +  LS    +  L EVF +   I     V     G+ +G+AF+ F S EDA EA 
Sbjct: 468 NRCLGIFGLSLYTQERGLREVFGRYGHISEVQVVYDRQTGRSRGFAFVYFKSSEDAHEAK 289

Query: 542 NSCNKMEIEGRTIRLELQGSNSRSQPSKTLFV 573
           + CN +EI+GR IR++   +     P+  +++
Sbjct: 288 DRCNGIEIDGRKIRVDFSITERAHTPTPGIYL 193

 Score = 52.0 bits (123), Expect = 9e-07,   Method: Compositional matrix adjust.
 Identities = 32/93 (34%), Positives = 46/93 (49%), Gaps = 3/93 (3%)
 Frame = -1

Query: 553 TIRLELQGSNSRSQPSKTLFVKGLSEDTTEETLKESF--EGSV-RARIVTDRETGSSKGF 609
           + R   QG      P++ L + GLS  T E  L+E F   G +   ++V DR+TG S+GF
Sbjct: 513 STRKRHQGDRENPDPNRCLGIFGLSLYTQERGLREVFGRYGHISEVQVVYDRQTGRSRGF 334

Query: 610 GFVDFNSXXXXXXXXXXXXXGEIDGNKVTLDWA 642
            FV F S              EIDG K+ +D++
Sbjct: 333 AFVYFKSSEDAHEAKDRCNGIEIDGRKIRVDFS 235

 Score = 43.9 bits (102), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 27/74 (36%), Positives = 36/74 (48%), Gaps = 5/74 (6%)
 Frame = -1

Query: 395 RTLLAKNLSFNITEDELKEVFEDAMEIRLVS-----QDGKSKGIAYIEFKSEADAEKNLE 449
           R L    LS    E  L+EVF     I  V      Q G+S+G A++ FKS  DA +  +
Sbjct: 465 RCLGIFGLSLYTQERGLREVFGRYGHISEVQVVYDRQTGRSRGFAFVYFKSSEDAHEAKD 286

Query: 450 EKQGAEIDGRSVSL 463
              G EIDGR + +
Sbjct: 285 RCNGIEIDGRKIRV 244
>39789
          Length = 361

 Score = 50.8 bits (120), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 25/78 (32%), Positives = 46/78 (58%), Gaps = 1/78 (1%)
 Frame = +1

Query: 486 SKTLVLSNLSYSATKETLEEVFEKATFIKVPQ-NPHGKPKGYAFIEFASFEDAKEALNSC 544
           +  L + NLSY   + +L++ F  AT  ++ +     KP+G+ F+EF++ +DA  A +S 
Sbjct: 85  TSVLFVGNLSYDTDQYSLKDAFPGATAARIAKFQDTQKPRGFGFVEFSTPDDAASAFDSG 264

Query: 545 NKMEIEGRTIRLELQGSN 562
            + E++GR ++L    SN
Sbjct: 265 ER-EVDGRQVKLSFASSN 315

 Score = 48.5 bits (114), Expect = 9e-06,   Method: Compositional matrix adjust.
 Identities = 31/102 (30%), Positives = 51/102 (50%)
 Frame = +1

Query: 541 LNSCNKMEIEGRTIRLELQGSNSRSQPSKTLFVKGLSEDTTEETLKESFEGSVRARIVTD 600
           +++C     E    +   Q   + S  +  LFV  LS DT + +LK++F G+  ARI   
Sbjct: 4   IDTCIYFHQE*FLNKRNKQHYMANS*STSVLFVGNLSYDTDQYSLKDAFPGATAARIAKF 183

Query: 601 RETGSSKGFGFVDFNSXXXXXXXXXXXXXGEIDGNKVTLDWA 642
           ++T   +GFGFV+F++              E+DG +V L +A
Sbjct: 184 QDTQKPRGFGFVEFSTPDDAASAFDSGER-EVDGRQVKLSFA 306
>28652
          Length = 918

 Score = 47.4 bits (111), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 54/229 (23%), Positives = 101/229 (44%), Gaps = 19/229 (8%)
 Frame = -2

Query: 405 NITEDELKEVFEDA---MEIRLVSQ--DGKSKGIAYIEFKSEADAEKNLEEKQGAEIDGR 459
           +I EDEL  +FED     ++RL+       ++G  ++ + ++  A + +++  G EI   
Sbjct: 701 DIFEDELIPLFEDCGTIWDLRLMMDPVSNLNRGYCFVTYTTKEAAAEAVKQHDGYEI--- 531

Query: 460 SVSLYYTGEKGQRQERTGKTSTWSGESKTLVLSNLSYSATKETLEEVFEKAT--FIKV-- 515
                       R+ +  K +  S  +  L + N+  S TKE + + FEK +   + V  
Sbjct: 530 ------------RKGKKLKVNI-SIPNLRLFVGNIPKSKTKEEILKEFEKHSEGLMDVIV 390

Query: 516 ---PQNPHGKPKGYAFIEFASFEDAKEALNSCNKMEIEGRTIRLELQGSNSRSQPS---- 568
                NP  K +G+AF+E+ + ++A  A               + +  ++ + +P+    
Sbjct: 389 YGSADNPKLKNRGFAFLEYDTHKNASAAKRRFTTGRFRVWQCDVIVDWADLQEEPNEETM 210

Query: 569 ---KTLFVKGLSEDTTEETLKESFEGSVRARIVTDRETGSSKGFGFVDF 614
              K L+V+ L+ D TE+ LKE F    +   V        K +GFV +
Sbjct: 209 SKVKVLYVRNLTGDVTEDDLKEKFGAYGKVERVK-----KIKDYGFVHY 78

 Score = 37.4 bits (85), Expect = 0.020,   Method: Compositional matrix adjust.
 Identities = 42/165 (25%), Positives = 80/165 (48%), Gaps = 17/165 (10%)
 Frame = -2

Query: 309 FNLFIGNLNPNKSVNELKFAISELFAKNDLAVVDVRT-GT-------NRKFGYVDFESAE 360
             LF+GN+  +K+  E    I + F K+   ++DV   G+       NR F ++++++ +
Sbjct: 488 LRLFVGNIPKSKTKEE----ILKEFEKHSEGLMDVIVYGSADNPKLKNRGFAFLEYDTHK 321

Query: 361 DLEKALE--LTG-LKVFGNEIKL------EKPKGRDSKKVRAARTLLAKNLSFNITEDEL 411
           +   A     TG  +V+  ++ +      E+P      KV+    L  +NL+ ++TED+L
Sbjct: 320 NASAAKRRFTTGRFRVWQCDVIVDWADLQEEPNEETMSKVKV---LYVRNLTGDVTEDDL 150

Query: 412 KEVFEDAMEIRLVSQDGKSKGIAYIEFKSEADAEKNLEEKQGAEI 456
           KE F    ++  V    K K   ++ ++   DA K L++  G +I
Sbjct: 149 KEKFGAYGKVERVK---KIKDYGFVHYEDREDALKALDDLHGEKI 24
>19868
          Length = 434

 Score = 47.0 bits (110), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 40/136 (29%), Positives = 68/136 (50%), Gaps = 12/136 (8%)
 Frame = +2

Query: 489 LVLSNLSYSATKETLEEVFEK---ATFIKVPQNPHGK-PKGYAFIEFASFEDAKEALNSC 544
           + +  LS+  + E+L + F K    T + V ++P  +  +G+ FI F       + L   
Sbjct: 5   MFVGGLSWQTSPESLRDYFNKFGEITEVMVMKDPTTRRSRGFGFITFGDPASVDKVLAQA 184

Query: 545 NKMEIEGRTIRLELQGSNSRSQP-----SKTLFVKGLSEDTTEETLKESFE--GSVR-AR 596
              E++G+ I  ++     R+ P     +K +FV GLS  TT E +K  FE  G +  A 
Sbjct: 185 TH-ELDGKKIDPKV-AFPRRAHPRMVTRTKKIFVGGLSAPTTLEDVKNYFEQFGPIEDAM 358

Query: 597 IVTDRETGSSKGFGFV 612
           ++ D++T   +GFGFV
Sbjct: 359 LMFDKQTNRHRGFGFV 406

 Score = 33.9 bits (76), Expect = 0.25,   Method: Compositional matrix adjust.
 Identities = 24/78 (30%), Positives = 37/78 (47%), Gaps = 3/78 (3%)
 Frame = +2

Query: 571 LFVKGLSEDTTEETLKESFE--GSV-RARIVTDRETGSSKGFGFVDFNSXXXXXXXXXXX 627
           +FV GLS  T+ E+L++ F   G +    ++ D  T  S+GFGF+ F             
Sbjct: 5   MFVGGLSWQTSPESLRDYFNKFGEITEVMVMKDPTTRRSRGFGFITFGDPASVDKVLAQA 184

Query: 628 XXGEIDGNKVTLDWAKPK 645
              E+DG K+    A P+
Sbjct: 185 TH-ELDGKKIDPKVAFPR 235
>02343
          Length = 1715

 Score = 47.0 bits (110), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 38/163 (23%), Positives = 78/163 (47%), Gaps = 6/163 (3%)
 Frame = -2

Query: 304  EPTTPFNLFIGNLNPNKSVNELKFAISELFAK--NDLAVVDVRTGTNRKFGYVDFESAED 361
            +P +  NL+I  L+PN +  +L   + + F    +  A++D  T   + +G+VDF++   
Sbjct: 1279 DPLSKTNLYIRGLSPNTTDKDL-VNLCQHFGTITSTKAIIDQTTNKCKGYGFVDFDAPGA 1103

Query: 362  LEKALELTGLKVFGNEIKLEKPKGRDSKKVRAARTLLAKNLSFNITEDELKEVFED---A 418
             E+A++   L+  G + ++ K + +D   +  A      NL  + TE  L+ +F+D    
Sbjct: 1102 AERAVQ--ALQAQGIQAQMAKQQEQDPTNLYIA------NLPLHFTEKHLEGLFKDYGTV 947

Query: 419  MEIRLVSQ-DGKSKGIAYIEFKSEADAEKNLEEKQGAEIDGRS 460
            +  R++ + DG S+ + +   +S    +  +       I G S
Sbjct: 946  ISTRILRKPDGISRCVGFARMESRDKCDTVINTFNNKMISGCS 818

 Score = 40.4 bits (93), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 20/53 (37%), Positives = 33/53 (62%), Gaps = 4/53 (7%)
 Frame = -2

Query: 568  SKT-LFVKGLSEDTTEE---TLKESFEGSVRARIVTDRETGSSKGFGFVDFNS 616
            SKT L+++GLS +TT++    L + F      + + D+ T   KG+GFVDF++
Sbjct: 1270 SKTNLYIRGLSPNTTDKDLVNLCQHFGTITSTKAIIDQTTNKCKGYGFVDFDA 1112
>02415
          Length = 2763

 Score = 46.6 bits (109), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 21/45 (46%), Positives = 32/45 (71%), Gaps = 3/45 (6%)
 Frame = -1

Query: 571  LFVKGLSEDTTEETLKESFE--GSV-RARIVTDRETGSSKGFGFV 612
            +FV GL   TT+ +L+E F+  G +  A ++TDR+TG S+G+GFV
Sbjct: 1920 IFVGGLPYHTTDHSLREYFDKFGDIDEAVVITDRQTGKSRGYGFV 1786
>08816
          Length = 566

 Score = 45.4 bits (106), Expect = 8e-05,   Method: Composition-based stats.
 Identities = 25/88 (28%), Positives = 48/88 (54%), Gaps = 3/88 (3%)
 Frame = +1

Query: 388 SKKVRAARTLLAKNLSFNITEDELKEVFEDAMEIR---LVSQDGKSKGIAYIEFKSEADA 444
           +++ +A  T+  +N+ F++T  EL+E F+D  +++   ++   G+  G A + F + ADA
Sbjct: 28  AQQGQARCTVTVRNVPFSLTWQELRERFQDIGDVKFSEILMDQGRPSGDAVVRFGTSADA 207

Query: 445 EKNLEEKQGAEIDGRSVSLYYTGEKGQR 472
            + +    G  IDGR+V +      G R
Sbjct: 208 MRAINLVDGTRIDGRTVRVVLRN*TGVR 291

 Score = 44.3 bits (103), Expect = 2e-04,   Method: Composition-based stats.
 Identities = 26/88 (29%), Positives = 47/88 (53%), Gaps = 3/88 (3%)
 Frame = +1

Query: 475 RTGKTSTWSGESK-TLVLSNLSYSATKETLEEVFEKATFIKVPQ--NPHGKPKGYAFIEF 531
           R G+     G+++ T+ + N+ +S T + L E F+    +K  +     G+P G A + F
Sbjct: 10  RNGQ*RAQQGQARCTVTVRNVPFSLTWQELRERFQDIGDVKFSEILMDQGRPSGDAVVRF 189

Query: 532 ASFEDAKEALNSCNKMEIEGRTIRLELQ 559
            +  DA  A+N  +   I+GRT+R+ L+
Sbjct: 190 GTSADAMRAINLVDGTRIDGRTVRVVLR 273
>28455
          Length = 573

 Score = 43.5 bits (101), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 22/71 (30%), Positives = 43/71 (60%), Gaps = 4/71 (5%)
 Frame = -1

Query: 397 LLAKNLSFNITEDELKEVFED---AMEIRLVS-QDGKSKGIAYIEFKSEADAEKNLEEKQ 452
           L  KNL F  + + L+ +F++     ++RLV+ + G SKG+AY+EF++E  A + + +  
Sbjct: 534 LFVKNLPFTCSAEALETIFKEHGKVKDVRLVTYRSGASKGLAYVEFETEEMATQAVMKTD 355

Query: 453 GAEIDGRSVSL 463
           G ++    +S+
Sbjct: 354 GLQVGDHMISV 322
>25950
          Length = 417

 Score = 42.7 bits (99), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 27/95 (28%), Positives = 47/95 (49%), Gaps = 4/95 (4%)
 Frame = -2

Query: 485 ESKTLVLSNLSYSATKETLEEVFEKATFIK----VPQNPHGKPKGYAFIEFASFEDAKEA 540
           +++++ + N+ Y A+ E LE  F     I     +     G PKG+A+IEF S E  + A
Sbjct: 287 DTRSVYVGNVDYGASAEELEAHFHGCGTINRVTILCNKADGHPKGFAYIEFGSKEYVETA 108

Query: 541 LNSCNKMEIEGRTIRLELQGSNSRSQPSKTLFVKG 575
           L + N+    GR I++  + +N     +   F +G
Sbjct: 107 L-AMNETLFRGRQIKVMTKRTNRPGLSTTNRFARG 6
>12506
          Length = 1056

 Score = 42.0 bits (97), Expect = 8e-04,   Method: Compositional matrix adjust.
 Identities = 19/37 (51%), Positives = 27/37 (72%)
 Frame = -3

Query: 522 KPKGYAFIEFASFEDAKEALNSCNKMEIEGRTIRLEL 558
           K +G+AFIEF   EDA  A+++ N+ E+ GRTIR+ L
Sbjct: 946 KHRGFAFIEFELAEDAAAAIDNMNESELFGRTIRVNL 836

 Score = 28.9 bits (63), Expect = 6.6,   Method: Compositional matrix adjust.
 Identities = 22/67 (32%), Positives = 36/67 (53%), Gaps = 6/67 (8%)
 Frame = -3

Query: 341 VDVRTGTNRKFGYVDFESAEDLEKALE-LTGLKVFGNEIK--LEKP---KGRDSKKVRAA 394
           +D  T  +R F +++FE AED   A++ +   ++FG  I+  L KP   K   S+ V A 
Sbjct: 964 LDYETEKHRGFAFIEFELAEDAAAAIDNMNESELFGRTIRVNLAKPMKVKEGASRAVWAD 785

Query: 395 RTLLAKN 401
            T L ++
Sbjct: 784 DTWLQQH 764
>03059
          Length = 1154

 Score = 41.6 bits (96), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 20/67 (29%), Positives = 38/67 (56%), Gaps = 6/67 (8%)
 Frame = -2

Query: 402 LSFNITEDELKEVFEDAMEIRLVS------QDGKSKGIAYIEFKSEADAEKNLEEKQGAE 455
           L+ N+ +D ++E+F     I+ +           SKG AY+E+++  DAEK ++   G +
Sbjct: 649 LTRNVNKDHIQEIFSLYGTIKFIDLPNDRIHPNTSKGHAYVEYENPEDAEKAVKYMDGGQ 470

Query: 456 IDGRSVS 462
           IDG+ ++
Sbjct: 469 IDGQEIT 449

 Score = 32.7 bits (73), Expect = 0.57,   Method: Compositional matrix adjust.
 Identities = 20/70 (28%), Positives = 40/70 (57%), Gaps = 6/70 (8%)
 Frame = -2

Query: 491 LSNLSYSATKETLEEVFE---KATFIKVPQNPHGKP---KGYAFIEFASFEDAKEALNSC 544
           +  L+ +  K+ ++E+F       FI +P N    P   KG+A++E+ + EDA++A+   
Sbjct: 658 VGRLTRNVNKDHIQEIFSLYGTIKFIDLP-NDRIHPNTSKGHAYVEYENPEDAEKAVKYM 482

Query: 545 NKMEIEGRTI 554
           +  +I+G+ I
Sbjct: 481 DGGQIDGQEI 452

 Score = 32.3 bits (72), Expect = 0.66,   Method: Compositional matrix adjust.
 Identities = 20/74 (27%), Positives = 39/74 (52%), Gaps = 3/74 (4%)
 Frame = -2

Query: 308 PFNLFIGNLNPNKSVNELK--FAISELFAKNDLAVVDVRTGTNRKFGYVDFESAEDLEKA 365
           P  + +G L  N + + ++  F++       DL    +   T++   YV++E+ ED EKA
Sbjct: 673 PTKVHVGRLTRNVNKDHIQEIFSLYGTIKFIDLPNDRIHPNTSKGHAYVEYENPEDAEKA 494

Query: 366 LE-LTGLKVFGNEI 378
           ++ + G ++ G EI
Sbjct: 493 VKYMDGGQIDGQEI 452
>31618
          Length = 716

 Score = 40.8 bits (94), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 28/83 (33%), Positives = 45/83 (54%), Gaps = 18/83 (21%)
 Frame = +1

Query: 552 RTIRLE-------LQGSNSRSQPSKT--------LFVKGLSEDTTEETLKESF--EGSVR 594
           RT+++E       LQ +  + QP +         LFV GLS +TTE+ L++ F   G + 
Sbjct: 196 RTLKMENRLPLPALQMAAQKMQPLRVTSVMMTEKLFVGGLSWETTEKELRDHFGKYGEIE 375

Query: 595 A-RIVTDRETGSSKGFGFVDFNS 616
           +  + TD +TG S+GF F+ F +
Sbjct: 376 SINVKTDPQTGRSRGFAFIVFTN 444
>20169
          Length = 1364

 Score = 40.8 bits (94), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 27/89 (30%), Positives = 47/89 (52%)
 Frame = -1

Query: 470  GQRQERTGKTSTWSGESKTLVLSNLSYSATKETLEEVFEKATFIKVPQNPHGKPKGYAFI 529
            G+R+E + +   +S + K  V   L +   K+ LE+ F K   +K       +P G+AF+
Sbjct: 1115 GRRKEMS-RHRDFSLDCKVYV-GELGHGCAKQELEDKFAKYGPLKNVWVAR-RPAGFAFV 945

Query: 530  EFASFEDAKEALNSCNKMEIEGRTIRLEL 558
            EF    DA++A+ + +   I GR  R+E+
Sbjct: 944  EFEDNRDAEDAVQALDGARINGRRARVEM 858

 Score = 31.6 bits (70), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 17/62 (27%), Positives = 30/62 (48%)
 Frame = -1

Query: 402  LSFNITEDELKEVFEDAMEIRLVSQDGKSKGIAYIEFKSEADAEKNLEEKQGAEIDGRSV 461
            L     + EL++ F     ++ V    +  G A++EF+   DAE  ++   GA I+GR  
Sbjct: 1049 LGHGCAKQELEDKFAKYGPLKNVWVARRPAGFAFVEFEDNRDAEDAVQALDGARINGRRA 870

Query: 462  SL 463
             +
Sbjct: 869  RV 864
>16016
          Length = 1364

 Score = 40.4 bits (93), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 31/115 (26%), Positives = 55/115 (47%), Gaps = 7/115 (6%)
 Frame = -2

Query: 486  SKTLVLSNLSYSATKETLEEVFEKATFIK---VPQNPHGK-PKGYAFIEFASFEDAKEAL 541
            ++ + +  +     + +L   FEK   I+   V ++P  K  + ++FI F + E+  E  
Sbjct: 1312 NRKVFIGGMHPDTDESSLRSYFEKYGDIRECIVVKDPATKRSRCFSFITFGNAENVDEVQ 1133

Query: 542  NSCNKMEIEGRTI---RLELQGSNSRSQPSKTLFVKGLSEDTTEETLKESFEGSV 593
                   I+GRT+   R   +        +K +FV GL +DTTEE L++ F G +
Sbjct: 1132 KD-RPHTIDGRTVETKRAMPREDTENHHQTKKMFVGGLKDDTTEEMLRKEFTGKI 971
>33516
          Length = 449

 Score = 40.0 bits (92), Expect = 0.003,   Method: Composition-based stats.
 Identities = 24/54 (44%), Positives = 35/54 (64%), Gaps = 3/54 (5%)
 Frame = +1

Query: 564 RSQPSKTLFVKGLSEDTTEETLKESFE--GSVRARIVT-DRETGSSKGFGFVDF 614
           R +P K +FV GLS DT +++L+  F   G +   IV  +++TG S+GFGFV F
Sbjct: 142 REEPGK-IFVGGLSWDTDQDSLQGYFSQFGEITDCIVMMNQQTGKSRGFGFVSF 300
>30672
          Length = 877

 Score = 40.0 bits (92), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 23/51 (45%), Positives = 34/51 (66%), Gaps = 3/51 (5%)
 Frame = +3

Query: 568 SKTLFVKGLSEDTTEETLKESFE--GSVR-ARIVTDRETGSSKGFGFVDFN 615
           SKTLFV+ L  +T+ E L E+FE  G ++ A +V  +E G  +GFG+V F+
Sbjct: 9   SKTLFVRNLPFETSNEKLLEAFEQVGPLKTAFVVAGKEPGKCRGFGYVQFS 161
>31265
          Length = 540

 Score = 39.7 bits (91), Expect = 0.005,   Method: Composition-based stats.
 Identities = 25/74 (33%), Positives = 42/74 (56%)
 Frame = +2

Query: 485 ESKTLVLSNLSYSATKETLEEVFEKATFIKVPQNPHGKPKGYAFIEFASFEDAKEALNSC 544
           + K L + NL  + T+ETL++VF +A   +  +    K + YAF+ F S EDA +A++  
Sbjct: 152 QVKILXVRNLMLTTTEETLKDVFSRAAGGREIERVK-KIRDYAFVHFRSREDAIKAMDVT 328

Query: 545 NKMEIEGRTIRLEL 558
           +   IEG  + + L
Sbjct: 329 DGSTIEGSQVEVVL 370

 Score = 36.2 bits (82), Expect = 0.051,   Method: Composition-based stats.
 Identities = 34/129 (26%), Positives = 56/129 (43%), Gaps = 8/129 (6%)
 Frame = +2

Query: 524 KGYAFIEFASFEDAKEALNSC--NKMEIEGRTIRLELQ------GSNSRSQPSKTLFVKG 575
           +G+AF+E+ S   A  A       ++++ G  I ++          ++ SQ  K L V+ 
Sbjct: 2   RGFAFVEYTSHRAAAMARRKLIPGRIQLWGHQIAVDWAEPEQDVDEDTMSQ-VKILXVRN 178

Query: 576 LSEDTTEETLKESFEGSVRARIVTDRETGSSKGFGFVDFNSXXXXXXXXXXXXXGEIDGN 635
           L   TTEETLK+ F  +   R +        + + FV F S               I+G+
Sbjct: 179 LMLTTTEETLKDVFSRAAGGREI--ERVKKIRDYAFVHFRSREDAIKAMDVTDGSTIEGS 352

Query: 636 KVTLDWAKP 644
           +V +  AKP
Sbjct: 353 QVEVVLAKP 379
>11687
          Length = 676

 Score = 38.9 bits (89), Expect = 0.006,   Method: Composition-based stats.
 Identities = 40/154 (25%), Positives = 72/154 (46%), Gaps = 11/154 (7%)
 Frame = +3

Query: 405 NITEDELKEVFED-----AMEIRLVSQDGKSKGIAYIEF---KSEADAEKNLEEKQGAEI 456
           N+ E+EL+++FED     ++ I      G+SKG  ++ F   K+  DA+  L   +   +
Sbjct: 180 NMDENELRKMFEDYGPVHSLNILRDKNTGQSKGCCFVTFFTRKAALDAQNALHNVKTMPM 359

Query: 457 DGRSVSLYYTGEKGQRQERTGKTSTWSGESKTLVLSNLSYSATKETLEEVFEKATFI--- 513
               V +    +    ++R G+ +    E + L +  LS   ++  +  +FE    I   
Sbjct: 360 MHHPVQM----KPADSEKRNGERNV---EERKLFVGMLSKKLSENDVRMLFESFGSIDDC 518

Query: 514 KVPQNPHGKPKGYAFIEFASFEDAKEALNSCNKM 547
            V ++ +G  +G AFI FAS    + A+NS   M
Sbjct: 519 TVLRDSNGTSRGCAFITFAS---RQCAMNSIKGM 611
>26197
          Length = 1365

 Score = 38.5 bits (88), Expect = 0.010,   Method: Compositional matrix adjust.
 Identities = 22/53 (41%), Positives = 35/53 (66%), Gaps = 3/53 (5%)
 Frame = -2

Query: 565  SQPSKTLFVKGLSEDTTEETLKESFE--GSVRARIV-TDRETGSSKGFGFVDF 614
            ++  + +FV GLS +T+ + L+E FE  G V +  + TD ++G S+GFGFV F
Sbjct: 1310 NEDDRKIFVGGLSWETSSKHLREYFEKFGEVTSCTLKTDLDSGKSRGFGFVVF 1152
>13822
          Length = 963

 Score = 38.5 bits (88), Expect = 0.011,   Method: Compositional matrix adjust.
 Identities = 23/100 (23%), Positives = 47/100 (47%), Gaps = 3/100 (3%)
 Frame = -1

Query: 367 ELTGLKVFGNEIKLEKPKGRDSKKVRAARTLLAKNLSFNITEDELKEV---FEDAMEIRL 423
           E+ G++V    I  E PK            L   N+ F   E +L+++   F   +++ +
Sbjct: 393 EVQGVQVPPQAISPEGPK-----------RLHVSNIPFRFREADLRQLLGPFGTILDVEI 247

Query: 424 VSQDGKSKGIAYIEFKSEADAEKNLEEKQGAEIDGRSVSL 463
           +  +  SKG  ++ F   A+AE+  ++  G  ++GR + +
Sbjct: 246 IFNERGSKGFGFVTFAHSAEAERARDKMNGTVVEGRKIEV 127

 Score = 28.5 bits (62), Expect = 9.7,   Method: Compositional matrix adjust.
 Identities = 13/41 (31%), Positives = 24/41 (58%)
 Frame = -1

Query: 524 KGYAFIEFASFEDAKEALNSCNKMEIEGRTIRLELQGSNSR 564
           KG+ F+ FA   +A+ A +  N   +EGR  ++E+  + +R
Sbjct: 225 KGFGFVTFAHSAEAERARDKMNGTVVEGR--KIEVNNATAR 109
>03903
          Length = 983

 Score = 38.1 bits (87), Expect = 0.011,   Method: Compositional matrix adjust.
 Identities = 27/105 (25%), Positives = 55/105 (52%), Gaps = 11/105 (10%)
 Frame = -1

Query: 386 RDSKKVRAARTLLAKNLSFNITEDELKEVF-----------EDAMEIRLVSQDGKSKGIA 434
           R+ K+   +R L  KNLS  +TE++L  VF           +   +IRL+ ++G+ KG A
Sbjct: 485 RNYKEGEPSRRLYIKNLSKQVTEEDLHWVFGRYVNWDKEEEKSIFDIRLM-KEGRMKGQA 309

Query: 435 YIEFKSEADAEKNLEEKQGAEIDGRSVSLYYTGEKGQRQERTGKT 479
           ++   +E  A K +++       G+ +++++   +  +Q+  GK+
Sbjct: 308 FVTLGTEEQARKAVKDTNAFVFKGKPIAVHFA--RSAKQQEEGKS 180
>03406
          Length = 1292

 Score = 38.1 bits (87), Expect = 0.013,   Method: Compositional matrix adjust.
 Identities = 22/53 (41%), Positives = 34/53 (64%), Gaps = 3/53 (5%)
 Frame = +3

Query: 565 SQPSKTLFVKGLSEDTTEETLKESFE--GSVRARIV-TDRETGSSKGFGFVDF 614
           ++  + +FV GLS +T  + L+E FE  G V +  + TD ++G S+GFGFV F
Sbjct: 228 NEDDRKIFVGGLSWETXSKHLREYFEKFGEVTSCTLKTDLDSGKSRGFGFVVF 386
>31938
          Length = 746

 Score = 38.1 bits (87), Expect = 0.013,   Method: Compositional matrix adjust.
 Identities = 20/74 (27%), Positives = 38/74 (51%)
 Frame = +3

Query: 392 RAARTLLAKNLSFNITEDELKEVFEDAMEIRLVSQDGKSKGIAYIEFKSEADAEKNLEEK 451
           R + T++ KN+  + T   L++ F D  +++     G   G+  + F  E DAE  +   
Sbjct: 252 RKSDTIVIKNVPLSCTWQTLRDKFRDVGDVKFAEIRGNDVGV--VRFFKERDAELAIALM 425

Query: 452 QGAEIDGRSVSLYY 465
            G+ +DGR++ + Y
Sbjct: 426 DGSRLDGRTIKVTY 467
>24983
          Length = 433

 Score = 37.4 bits (85), Expect = 0.021,   Method: Composition-based stats.
 Identities = 19/41 (46%), Positives = 29/41 (70%), Gaps = 3/41 (7%)
 Frame = -2

Query: 575 GLSEDTTEETLKESFE--GSV-RARIVTDRETGSSKGFGFV 612
           GL   TT+ +L+E F+  G +  A ++TDR+TG S+G+GFV
Sbjct: 297 GLPYHTTDHSLREYFDKFGDIDEAVVITDRQTGKSRGYGFV 175
>17681
          Length = 964

 Score = 37.0 bits (84), Expect = 0.028,   Method: Compositional matrix adjust.
 Identities = 21/47 (44%), Positives = 28/47 (59%), Gaps = 3/47 (6%)
 Frame = +2

Query: 571 LFVKGLSEDTTEETLKESFE--GSV-RARIVTDRETGSSKGFGFVDF 614
           +FV  LS +   ETL+E+F   G +   RIV D +T  SKG+ FV F
Sbjct: 38  IFVGDLSPEIETETLREAFAPFGEISNCRIVRDPQTMKSKGYAFVSF 178

 Score = 35.0 bits (79), Expect = 0.091,   Method: Compositional matrix adjust.
 Identities = 42/209 (20%), Positives = 68/209 (32%), Gaps = 51/209 (24%)
 Frame = +2

Query: 489 LVLSNLSYSATKETLEEVF------EKATFIKVPQNPHGKPKGYAFIEFASFEDAKEALN 542
           + + +LS     ETL E F           ++ PQ    K KGYAF+ F    +A+ A+ 
Sbjct: 38  IFVGDLSPEIETETLREAFAPFGEISNCRIVRDPQT--MKSKGYAFVSFVKKAEAENAIQ 211

Query: 543 SCNKMEIEGRTIRLEL-------------------------------------------- 558
           + N   I  R+IR                                               
Sbjct: 212 AMNGQWIGSRSIRTNWSTRKLPPPRESSKSGGQGGGMGGMGGCGGGAGNGIKNNQRHTFE 391

Query: 559 QGSNSRSQPSKTLFVKGLSEDT-TEETLKESFEGSVRARIVTDRETGSSKGFGFVDFNSX 617
           +  N  S  + T++  G   +  ++E + + F   ++   + D      KGF F+ F + 
Sbjct: 392 EVYNQSSPTNTTVYCGGFPPNVISDELMHKHF---MQFGPIQDVRVFKDKGFAFIKFVTK 562

Query: 618 XXXXXXXXXXXXGEIDGNKVTLDWAKPKG 646
                        E+ GN V   W K  G
Sbjct: 563 EAAARAIEHTHISEVHGNHVKCFWGKENG 649
>23720
          Length = 739

 Score = 37.0 bits (84), Expect = 0.031,   Method: Compositional matrix adjust.
 Identities = 32/149 (21%), Positives = 59/149 (39%), Gaps = 36/149 (24%)
 Frame = -1

Query: 351 FGYVDFESAEDLEKAL-ELTGLKVFGNEIKLEKPKG------------------------ 385
           +G+V+FE   D + A+ EL G  + G  + +E  +G                        
Sbjct: 580 YGFVEFEDFRDADDAVYELNGKDLCGERVIIEHARGTSRGGGGGGGGRDRDRDGGGYYDR 401

Query: 386 -RDSKK----------VRAARTLLAKNLSFNITEDELKEVFEDAMEIRLVSQDGKSKGIA 434
              S++           R    L+ +NLS  ++  +LK+    A E+       + +   
Sbjct: 400 GGSSRRSGWGDKYGPPTRTDYRLVVENLSSRVSWQDLKDYMRQAGEVTYADAHKRHRNEG 221

Query: 435 YIEFKSEADAEKNLEEKQGAEIDGRSVSL 463
            IEF + +D +  L++    EI+GR + L
Sbjct: 220 IIEFATSSDLKNALDKLDNTEINGRKIKL 134

 Score = 32.0 bits (71), Expect = 0.99,   Method: Compositional matrix adjust.
 Identities = 18/69 (26%), Positives = 31/69 (44%)
 Frame = -1

Query: 489 LVLSNLSYSATKETLEEVFEKATFIKVPQNPHGKPKGYAFIEFASFEDAKEALNSCNKME 548
           + +  L Y A ++ +E  F     +    N      GY F+EF  F DA +A+   N  +
Sbjct: 679 VYIGRLPYQAREKDIERFFRGYGRV----NDIMLKNGYGFVEFEDFRDADDAVYELNGKD 512

Query: 549 IEGRTIRLE 557
           + G  + +E
Sbjct: 511 LCGERVIIE 485
>04988
          Length = 705

 Score = 36.6 bits (83), Expect = 0.033,   Method: Composition-based stats.
 Identities = 32/152 (21%), Positives = 57/152 (37%), Gaps = 39/152 (25%)
 Frame = -3

Query: 351 FGYVDFESAEDLEKAL-ELTGLKVFGNEIKLEKPKG------------------------ 385
           +G+V+FE   D + A+ EL G  + G  + +E  +G                        
Sbjct: 547 YGFVEFEDFRDADDAVYELNGKDLCGERVIIEHARGTSRGGGGGGGGRDRDRDGGGYYDR 368

Query: 386 --------------RDSKKVRAARTLLAKNLSFNITEDELKEVFEDAMEIRLVSQDGKSK 431
                         R     R    L+ +NLS  ++  +LK+    A E+       + +
Sbjct: 367 GGSSRRSGWGDKVPRYGPPTRTDYRLVVENLSSRVSWQDLKDYMRQAGEVTYADAHKRHR 188

Query: 432 GIAYIEFKSEADAEKNLEEKQGAEIDGRSVSL 463
               IEF + +D +  L++    EI+GR + L
Sbjct: 187 NEGIIEFATSSDLKNALDKLDNTEINGRKIKL 92

 Score = 28.9 bits (63), Expect = 8.3,   Method: Composition-based stats.
 Identities = 12/33 (36%), Positives = 19/33 (57%)
 Frame = -3

Query: 525 GYAFIEFASFEDAKEALNSCNKMEIEGRTIRLE 557
           GY F+EF  F DA +A+   N  ++ G  + +E
Sbjct: 550 GYGFVEFEDFRDADDAVYELNGKDLCGERVIIE 452
>32386
          Length = 674

 Score = 36.6 bits (83), Expect = 0.035,   Method: Compositional matrix adjust.
 Identities = 24/82 (29%), Positives = 39/82 (47%), Gaps = 3/82 (3%)
 Frame = +1

Query: 569 KTLFVKGLSEDTTEETLKESFEGS---VRARIVTDRETGSSKGFGFVDFNSXXXXXXXXX 625
           + LF+ GLS +T E++L+  FE     V   ++ D  +  S+GFGF+ +           
Sbjct: 301 RKLFIGGLSYETDEDSLRSHFETWGEIVDCIVMRDSNSKRSRGFGFITYKDAESIDQAQA 480

Query: 626 XXXXGEIDGNKVTLDWAKPKGE 647
                +IDG +V    A P+ E
Sbjct: 481 NRPH-KIDGREVDTKRAMPREE 543
>05273
          Length = 1009

 Score = 36.2 bits (82), Expect = 0.041,   Method: Compositional matrix adjust.
 Identities = 17/36 (47%), Positives = 27/36 (75%), Gaps = 3/36 (8%)
 Frame = -1

Query: 580 TTEETLKESFE--GSV-RARIVTDRETGSSKGFGFV 612
           TT+ +L+E F+  G +  A ++TDR+TG S+G+GFV
Sbjct: 166 TTDHSLREYFDKFGDIDEAVVITDRQTGKSRGYGFV 59
>11126
          Length = 1061

 Score = 36.2 bits (82), Expect = 0.042,   Method: Compositional matrix adjust.
 Identities = 23/82 (28%), Positives = 40/82 (48%), Gaps = 6/82 (7%)
 Frame = -3

Query: 487 KTLVLSNLSYSATKETLEEVFEKATFIK----VPQNPHGKPKGYAFIEFASFEDAKEALN 542
           +++ + N+ Y AT E LE+ F     +     +     G PKG+A++EFA  +    A  
Sbjct: 630 RSVYVGNVDYGATAEELEQHFHGCGSVNRVTILCDKYSGHPKGFAYVEFADKDSVVTA-- 457

Query: 543 SCNKME--IEGRTIRLELQGSN 562
            C  M+    GR I++  + +N
Sbjct: 456 KCTGMDSLFRGRQIKVTPKRTN 391
>03856
          Length = 1292

 Score = 31.6 bits (70), Expect(2) = 0.062,   Method: Compositional matrix adjust.
 Identities = 16/43 (37%), Positives = 27/43 (62%)
 Frame = +2

Query: 429 KSKGIAYIEFKSEADAEKNLEEKQGAEIDGRSVSLYYTGEKGQ 471
           K+ G A++EF SE+  +KN +  QGA+I  + + + Y G K +
Sbjct: 767 KTVGYAFLEFASESMTDKNYKLLQGAKIKDQELVVDYVGLKSK 895

 Score = 22.7 bits (47), Expect(2) = 0.062,   Method: Compositional matrix adjust.
 Identities = 15/36 (41%), Positives = 18/36 (50%)
 Frame = +3

Query: 396 TLLAKNLSFNITEDELKEVFEDAMEIRLVSQDGKSK 431
           TL  KNL       +LK +  D  E+RL    GKSK
Sbjct: 651 TLFVKNLPAGTVVKDLKALSTDVKEVRL-RISGKSK 755
>03000
          Length = 778

 Score = 35.0 bits (79), Expect = 0.090,   Method: Compositional matrix adjust.
 Identities = 26/82 (31%), Positives = 40/82 (48%), Gaps = 3/82 (3%)
 Frame = +3

Query: 569 KTLFVKGLSEDTTEETLKESFE--GSVRARIVT-DRETGSSKGFGFVDFNSXXXXXXXXX 625
           + LF+ GLS +T E++L+  FE  G +   IV  D  +  S+GFGF+ +           
Sbjct: 87  RKLFIGGLSYETDEDSLRSHFETWGEIVDCIVMRDSNSKRSRGFGFITYKDAESIDQAQA 266

Query: 626 XXXXGEIDGNKVTLDWAKPKGE 647
                +IDG +V    A P+ E
Sbjct: 267 NRPH-KIDGREVDTKRAMPREE 329
>08958
          Length = 680

 Score = 34.3 bits (77), Expect = 0.16,   Method: Compositional matrix adjust.
 Identities = 42/146 (28%), Positives = 68/146 (46%), Gaps = 8/146 (5%)
 Frame = +2

Query: 311 LFIGNLNPNKSVNELKFAISELFAKNDLAVVDVRTGTNRKFGYVDFESAEDLEKA-LELT 369
           LF+GNL P+ S ++ K   S  F +   A V+    + R FG++  +   + E A   L 
Sbjct: 74  LFVGNLTPDVSEDDFKKLFSP-FGEVSEAYVN----SGRGFGFIRLDYRHNAEAAKAALD 238

Query: 370 GLKVFGNEIKLEKPKGRDSKKVRAAR---TLLAKNLSFNITEDELKEVFEDAME----IR 422
           GL          + KGR S +VR A     L  KNL   ++ + L++ F    +    I 
Sbjct: 239 GL----------QRKGR-SLRVRYATHGAALKVKNLHPYVSNELLEQAFTQFGDLERAIV 385

Query: 423 LVSQDGKSKGIAYIEFKSEADAEKNL 448
           +V + G+S G   +EF  +  A++ L
Sbjct: 386 IVDERGRSTGEGVVEFVRKPGAQQAL 463
>12350
          Length = 975

 Score = 34.3 bits (77), Expect = 0.17,   Method: Compositional matrix adjust.
 Identities = 20/56 (35%), Positives = 29/56 (51%), Gaps = 3/56 (5%)
 Frame = -2

Query: 562 NSRSQPSKTLFVKGLSEDTTEETLKESFE---GSVRARIVTDRETGSSKGFGFVDF 614
           +S  Q    L V GL   +TE+ L+  F      +  ++  D +TG SKGFGF+ F
Sbjct: 641 SSSRQKCSDLIVLGLPWKSTEDDLRSYFSQFGDLLMVQVKKDPKTGQSKGFGFIRF 474

 Score = 30.8 bits (68), Expect = 1.8,   Method: Compositional matrix adjust.
 Identities = 26/133 (19%), Positives = 57/133 (42%), Gaps = 4/133 (3%)
 Frame = -2

Query: 310 NLFIGNLNPNKSVNELKFAISELFAKNDLAVVDVR----TGTNRKFGYVDFESAEDLEKA 365
           +L +  L    + ++L+   S+     DL +V V+    TG ++ FG++ F   E   K 
Sbjct: 617 DLIVLGLPWKSTEDDLRSYFSQF---GDLLMVQVKKDPKTGQSKGFGFIRFAEYESQLKC 447

Query: 366 LELTGLKVFGNEIKLEKPKGRDSKKVRAARTLLAKNLSFNITEDELKEVFEDAMEIRLVS 425
           +    + + G    +  P  ++  +    R +     + ++T D+L++ F    E+  V 
Sbjct: 446 MAQRHM-IDGRWCDVRIPNSKEGAQQLMNRKIFVGRCTDDMTADDLRQFFSKFGEVVDVF 270

Query: 426 QDGKSKGIAYIEF 438
                +  A++ F
Sbjct: 269 IPRPFRAFAFVSF 231
>11108
          Length = 493

 Score = 34.3 bits (77), Expect = 0.18,   Method: Composition-based stats.
 Identities = 22/81 (27%), Positives = 39/81 (48%), Gaps = 15/81 (18%)
 Frame = -1

Query: 479 TSTWSGE-----------SKTLVLSNLSYSATKETLEEVFEKATFIKV----PQNPHGKP 523
           T TWSG+           S  + L  + +  ++++L ++F+    IKV     +    +P
Sbjct: 349 TCTWSGQLPPRSHRMLNYSPKVFLGGIPWDISEQSLIQIFKPFGSIKVEWPGKEQQAAQP 170

Query: 524 KGYAFIEFASFEDAKEALNSC 544
           KGY +I F S +  K  L++C
Sbjct: 169 KGYVYIIFESDKQVKALLSAC 107
>12096
          Length = 1585

 Score = 33.9 bits (76), Expect = 0.20,   Method: Compositional matrix adjust.
 Identities = 20/54 (37%), Positives = 32/54 (59%), Gaps = 3/54 (5%)
 Frame = -3

Query: 566  QPSKTLFVKGLSEDTTE-ETLKESFEGSVRARIV--TDRETGSSKGFGFVDFNS 616
            +PS T+ ++GLS    E + ++E     +  + V    R TG+S+GFGFV+F S
Sbjct: 1232 EPSATILLRGLSNTLVENDIIQELIRIGMPPKDVRFMRRVTGASRGFGFVEFQS 1071
>11579
          Length = 1307

 Score = 32.7 bits (73), Expect = 0.49,   Method: Compositional matrix adjust.
 Identities = 11/35 (31%), Positives = 24/35 (68%)
 Frame = +3

Query: 524 KGYAFIEFASFEDAKEALNSCNKMEIEGRTIRLEL 558
           +G+AF+ F    DA++A++S +   ++GR +R ++
Sbjct: 6   RGFAFVRFYDRRDAEDAMDSMDGALLDGREVRCQM 110

 Score = 32.3 bits (72), Expect = 0.60,   Method: Compositional matrix adjust.
 Identities = 13/32 (40%), Positives = 19/32 (59%)
 Frame = +3

Query: 430 SKGIAYIEFKSEADAEKNLEEKQGAEIDGRSV 461
           S+G A++ F    DAE  ++   GA +DGR V
Sbjct: 3   SRGFAFVRFYDRRDAEDAMDSMDGALLDGREV 98
>11019
          Length = 552

 Score = 32.7 bits (73), Expect = 0.54,   Method: Compositional matrix adjust.
 Identities = 19/45 (42%), Positives = 27/45 (60%), Gaps = 3/45 (6%)
 Frame = -1

Query: 573 VKGLSEDTTEETLKESFE--GSVRARIVT-DRETGSSKGFGFVDF 614
           + GLS  TT ETL+  FE  G ++  +V  D  +  S+GFGFV +
Sbjct: 552 IGGLSWQTTTETLRSYFEKFGEIKESMVMKDPTSKRSRGFGFVTY 418
>31310
          Length = 469

 Score = 32.0 bits (71), Expect = 0.95,   Method: Composition-based stats.
 Identities = 17/46 (36%), Positives = 27/46 (58%)
 Frame = -3

Query: 522 KPKGYAFIEFASFEDAKEALNSCNKMEIEGRTIRLELQGSNSRSQP 567
           K KG++FIE+   E A+ AL   N + I GR I++    +  ++QP
Sbjct: 206 KHKGFSFIEYDVPEAAQLALEQMNGVMIGGRNIKVGRPSNMPQAQP 69
>16427
          Length = 1313

 Score = 31.6 bits (70), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 22/75 (29%), Positives = 36/75 (48%), Gaps = 3/75 (4%)
 Frame = +1

Query: 571 LFVKGLSEDTTEETLKESFEGSVR---ARIVTDRETGSSKGFGFVDFNSXXXXXXXXXXX 627
           LFV GL+E+  E+ L+  F    R   + ++ D+    S+GFGFV + +           
Sbjct: 142 LFVGGLAEEIDEKVLEREFSKFGRITESMVIRDKVRQVSRGFGFVTYENPMDAEEAVKHM 321

Query: 628 XXGEIDGNKVTLDWA 642
              EI G K+ ++ A
Sbjct: 322 DGKEILGKKLHVEDA 366
>00781
          Length = 3170

 Score = 31.6 bits (70), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 18/67 (26%), Positives = 37/67 (55%), Gaps = 4/67 (5%)
 Frame = -1

Query: 485  ESKTLVLSNLSYSATKETLEEVFEKA---TFIKVPQNPHGKP-KGYAFIEFASFEDAKEA 540
            +++T+ +       ++E +  +F K    T++ +P     +  KGYAF+EF S E+A +A
Sbjct: 2726 DARTVYVEGFHKFTSREWISRMFSKCGTVTYVSLPCFKTTREIKGYAFVEFQSPEEAVKA 2547

Query: 541  LNSCNKM 547
            +   N++
Sbjct: 2546 VQMLNRV 2526
>01278
          Length = 1082

 Score = 31.2 bits (69), Expect = 1.7,   Method: Compositional matrix adjust.
 Identities = 19/61 (31%), Positives = 30/61 (49%), Gaps = 4/61 (6%)
 Frame = +2

Query: 485 ESKTLVLSNLSYSATKETLEEVFEK----ATFIKVPQNPHGKPKGYAFIEFASFEDAKEA 540
           E+ T+ ++NLS    +  L+E+F      +          G+ KG+AFI F   EDA  A
Sbjct: 629 EAATIRVTNLSEDTRESDLQELFRPFGPISRIYLAKDKVTGQSKGFAFINFHRREDASRA 808

Query: 541 L 541
           +
Sbjct: 809 I 811
>02347
          Length = 928

 Score = 30.8 bits (68), Expect = 1.7,   Method: Compositional matrix adjust.
 Identities = 21/82 (25%), Positives = 41/82 (50%), Gaps = 3/82 (3%)
 Frame = -3

Query: 489 LVLSNLSYSATKETLEEVFEKATFIK---VPQNPHGKPKGYAFIEFASFEDAKEALNSCN 545
           + + +L   A+++ +E  F     ++   V +NP     G+AF+EF    DA +A+ + +
Sbjct: 740 IYVGDLPPDASEKEVERAFNYYGHLRNVWVARNP----PGFAFVEFEDTRDADDAVRALD 573

Query: 546 KMEIEGRTIRLELQGSNSRSQP 567
              + G  +R+E   S  R +P
Sbjct: 572 GTVVCGNRVRVE--HSTGRVRP 513
>02809
          Length = 1475

 Score = 30.4 bits (67), Expect = 2.6,   Method: Compositional matrix adjust.
 Identities = 20/69 (28%), Positives = 34/69 (49%)
 Frame = -1

Query: 475  RTGKTSTWSGESKTLVLSNLSYSATKETLEEVFEKATFIKVPQNPHGKPKGYAFIEFASF 534
            R  +   +S + K  V   L +   K+ LE+ F K   +K       +P G+AF+EF   
Sbjct: 1367 RMSRHRDFSLDCKVYV-GELGHGCAKQELEDKFAKYGPLKNVWVAR-RPAGFAFVEFEDN 1194

Query: 535  EDAKEALNS 543
             DA++A+ +
Sbjct: 1193 RDAEDAVQA 1167
>11102
          Length = 1019

 Score = 30.0 bits (66), Expect = 2.9,   Method: Compositional matrix adjust.
 Identities = 13/39 (33%), Positives = 21/39 (53%)
 Frame = +1

Query: 516 PQNPHGKPKGYAFIEFASFEDAKEALNSCNKMEIEGRTI 554
           P  PHG  KGYA IE+ +    ++   + N  E+ G+ +
Sbjct: 34  PGPPHGLLKGYALIEYETSRRRRQPWTNLNGTELLGQKL 150
>29364
          Length = 1126

 Score = 30.0 bits (66), Expect = 3.1,   Method: Compositional matrix adjust.
 Identities = 12/33 (36%), Positives = 19/33 (57%)
 Frame = +1

Query: 525 GYAFIEFASFEDAKEALNSCNKMEIEGRTIRLE 557
           GY F+EF  + DA +A+   N  E+ G  + +E
Sbjct: 70  GYGFVEFEDYRDADDAVYELNGKELLGERVVVE 168
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|112363082|ref|NP_032710.2| neogenin isoform 1 [Mus
musculus]
         (1492 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

29990                                                                  71   3e-12
30103                                                                  67   4e-11
17679                                                                  64   3e-10
19544                                                                  63   8e-10
17229                                                                  59   2e-08
06028                                                                  55   2e-07
20110                                                                  47   2e-07
08294                                                                  53   9e-07
27666                                                                  53   1e-06
38127                                                                  49   1e-05
13135                                                                  49   1e-05
25766                                                                  47   2e-05
11855                                                                  48   4e-05
35419                                                                  41   0.003
20244                                                                  32   0.004
36498                                                                  36   0.028
18345                                                                  38   0.034
32888                                                                  34   0.040
11788                                                                  35   0.16 
37675                                                                  35   0.29 
11732                                                                  34   0.36 
17530                                                                  33   0.66 
29881                                                                  33   0.75 
34369                                                                  33   0.78 
04057                                                                  33   1.2  
33163                                                                  32   2.4  
29932                                                                  31   4.3  
>29990
          Length = 434

 Score = 71.2 bits (173), Expect = 3e-12,   Method: Compositional matrix adjust.
 Identities = 38/108 (35%), Positives = 51/108 (47%), Gaps = 4/108 (3%)
 Frame = +3

Query: 285 GLPAPVVRWMKNEEVLDTESSGRLVLLAGGCLEISDVTEDDAGTYFCIADN-GNKTVEAQ 343
           G P P + WM N   ++     R  LL  G L I D  +DD G Y CIA N   +T   Q
Sbjct: 6   GKPVPEIVWMHNNNRVEISGDSRFSLLHDGTLMIEDAQDDDRGVYECIARNVAGETHSNQ 185

Query: 344 AELTV---QVPPGFLKQPANIYAHESMDIVFECEVTGKPTPTVKWVKN 388
            EL     +V P F ++P +I   E   +   C+ +G P PT  W +N
Sbjct: 186 VELRYFGERVAPXFTQRPQDIVTVEGQTVQLVCQASGHPRPTFSWTRN 329

 Score = 63.2 bits (152), Expect = 8e-10,   Method: Compositional matrix adjust.
 Identities = 39/112 (34%), Positives = 53/112 (47%), Gaps = 2/112 (1%)
 Frame = +3

Query: 191 VPFVRW--EQNRQPLLLDDRIVKLPSGTLVISNATEGDGGLYRCIVESGGPPKFSDEAEL 248
           VP + W    NR  +  D R   L  GTL+I +A + D G+Y CI  +      S++ EL
Sbjct: 15  VPEIVWMHNNNRVEISGDSRFSLLHDGTLMIEDAQDDDRGVYECIARNVAGETHSNQVEL 194

Query: 249 KVLQDPEEIVDLVFLMRPSSMMKVTGQSAVLPCVVSGLPAPVVRWMKNEEVL 300
           +      E V   F  RP  ++ V GQ+  L C  SG P P   W +N E L
Sbjct: 195 RYFG---ERVAPXFTQRPQDIVTVEGQTVQLVCQASGHPRPTFSWTRNLEQL 341

 Score = 46.2 bits (108), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 32/118 (27%), Positives = 49/118 (41%), Gaps = 3/118 (2%)
 Frame = +3

Query: 89  SEPSPNIEWKKDGTFLNLESDDRRQLLPDGSLFISNVVHSKHNKPDEGFYQCVATVDNLG 148
            +P P I W  +   + +  D R  LL DG+L I +         D G Y+C+A  +  G
Sbjct: 6   GKPVPEIVWMHNNNRVEISGDSRFSLLHDGTLMIEDA-----QDDDRGVYECIAR-NVAG 167

Query: 149 TIVSRTAKLTVAG---LPRFTSQPEPSSVYVGNSAILNCEVNADLVPFVRWEQNRQPL 203
              S   +L   G    P FT +P+      G +  L C+ +    P   W +N + L
Sbjct: 168 ETHSNQVELRYFGERVAPXFTQRPQDIVTVEGQTVQLVCQASGHPRPTFSWTRNLEQL 341

 Score = 32.7 bits (73), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 16/41 (39%), Positives = 22/41 (53%)
 Frame = +2

Query: 192 PFVRWEQNRQPLLLDDRIVKLPSGTLVISNATEGDGGLYRC 232
           P ++ +Q  + + LD RI     GTL I N  E D G Y+C
Sbjct: 305 PHLQLDQEPRAVGLDPRITDHEDGTLTIRNVQESDRGDYQC 427

 Score = 30.4 bits (67), Expect = 5.7,   Method: Compositional matrix adjust.
 Identities = 12/35 (34%), Positives = 17/35 (48%)
 Frame = +3

Query: 66  FLVEPVDTLSVRGSSVILNCSAYSEPSPNIEWKKD 100
           F   P D ++V G +V L C A   P P   W ++
Sbjct: 225 FTQRPQDIVTVEGQTVQLVCQASGHPRPTFSWTRN 329
>30103
          Length = 341

 Score = 67.4 bits (163), Expect = 4e-11,   Method: Compositional matrix adjust.
 Identities = 32/82 (39%), Positives = 48/82 (58%), Gaps = 1/82 (1%)
 Frame = +1

Query: 670 NLSLEVRNSKSIVIHWQPPSSTTQNGQITGYKIRY-RKASRKSDVTETLVTGTQLSQLIE 728
           NLSL+  N   +++ W+PP++  +NG +  YK++Y RK SR+ DV   +         + 
Sbjct: 1   NLSLKFSNDSLVLLKWRPPAARQKNGVLQSYKVQYRRKGSRRGDVCSVITPSQDHHFFLT 180

Query: 729 GLDRGTEYNFRVAALTVNGTGP 750
            +  G  Y  RVAA+TVNGTGP
Sbjct: 181 DVTSGQTYKVRVAAMTVNGTGP 246
>17679
          Length = 509

 Score = 64.3 bits (155), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 48/142 (33%), Positives = 76/142 (53%), Gaps = 9/142 (6%)
 Frame = +3

Query: 539 VYIFKVMAQNKHGSGESSAPL-RVE--TQPEVQLPGPAP-NIRAYATSPTSITVTWETPL 594
           V   K + ++K+ + E+S+ L  +E   Q  V+ PG AP N+RA A S T+I V+W  P 
Sbjct: 24  VLQLKDVKESKNFTCEASSDLGNIERIVQVLVEAPGTAPRNVRARAASSTTIVVSWSEPE 203

Query: 595 SGNGEIQNYKLYYMEKGTD-----KEQDIDVSSHSYTINGLKKYTEYSFRVVAYNKHGPG 649
             NG IQ Y+++Y  K  +     ++Q++   +   TI+GL     Y+  ++AY+  GPG
Sbjct: 204 IPNGIIQGYRVFYTRKPEEPVFFWEQQEVKNDNRLTTISGLDPNQTYTISILAYSSIGPG 383

Query: 650 VSTQDVAVRTLSDVPSAAPQNL 671
             +  + V T   VP   P NL
Sbjct: 384 PMSHPIQVLTTQGVP-YQPLNL 446

 Score = 45.4 bits (106), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 33/99 (33%), Positives = 48/99 (48%), Gaps = 1/99 (1%)
 Frame = +3

Query: 985  PTSPPKDVTVVSKEGKPRTIIVNWQPPSEANGKITGYIIYYSTDVNAEIHDWVIEPVVG- 1043
            P + P++V   ++     TI+V+W  P   NG I GY ++Y+      +  W  + V   
Sbjct: 126  PGTAPRNVR--ARAASSTTIVVSWSEPEIPNGIIQGYRVFYTRKPEEPVFFWEQQEVKND 299

Query: 1044 NRLTHQIQELTLDTPYYFKIQARNSKGMGPMSEAVQFRT 1082
            NRLT  I  L  +  Y   I A +S G GPMS  +Q  T
Sbjct: 300  NRLT-TISGLDPNQTYTISILAYSSIGPGPMSHPIQVLT 413

 Score = 44.3 bits (103), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 26/73 (35%), Positives = 41/73 (56%), Gaps = 6/73 (8%)
 Frame = +3

Query: 783 TSIVVSWTPPENQNIVVRGYAIGYG------IGSPHAQTIKVDYKQRYYTIENLDPSSHY 836
           T+IVVSW+ PE  N +++GY + Y       +     Q +K D   R  TI  LDP+  Y
Sbjct: 171 TTIVVSWSEPEIPNGIIQGYRVFYTRKPEEPVFFWEQQEVKND--NRLTTISGLDPNQTY 344

Query: 837 VITLKAFNNVGEG 849
            I++ A++++G G
Sbjct: 345 TISILAYSSIGPG 383

 Score = 43.5 bits (101), Expect = 6e-04,   Method: Compositional matrix adjust.
 Identities = 34/128 (26%), Positives = 54/128 (42%), Gaps = 2/128 (1%)
 Frame = +3

Query: 657 VRTLSDVPSAAPQNLSLEVRNSKSIVIHWQPPSSTTQNGQITGYKIRYRKASRKSDV--T 714
           V+ L + P  AP+N+     +S +IV+ W  P     NG I GY++ Y +   +      
Sbjct: 105 VQVLVEAPGTAPRNVRARAASSTTIVVSWSEPE--IPNGIIQGYRVFYTRKPEEPVFFWE 278

Query: 715 ETLVTGTQLSQLIEGLDRGTEYNFRVAALTVNGTGPATDWLSAETFESDLDETRVPEVPS 774
           +  V        I GLD    Y   + A +  G GP +  +   T +       VP  P 
Sbjct: 279 QQEVKNDNRLTTISGLDPNQTYTISILAYSSIGPGPMSHPIQVLTTQG------VPYQPL 440

Query: 775 SLHVRPLV 782
           +LH  P++
Sbjct: 441 NLHADPIL 464

 Score = 38.9 bits (89), Expect = 0.018,   Method: Compositional matrix adjust.
 Identities = 46/166 (27%), Positives = 70/166 (42%), Gaps = 6/166 (3%)
 Frame = +3

Query: 404 HNLQVLGLVKSDEGFYQCIAENDVGNAQAGAQLIILEHDVAIXXXXXXXXXXXXXDHLAP 463
            N+  L  VK  + F  C A +D+GN +   Q+++                       AP
Sbjct: 18  RNVLQLKDVKESKNF-TCEASSDLGNIERIVQVLVE----------------------AP 128

Query: 464 ATTGPLPSAPRDVVASLVSTRFIKLTWRTPASDPHGDNLTYSVFYTK---EGV---ARER 517
            T      APR+V A   S+  I ++W  P   P+G    Y VFYT+   E V    ++ 
Sbjct: 129 GT------APRNVRARAASSTTIVVSWSEP-EIPNGIIQGYRVFYTRKPEEPVFFWEQQE 287

Query: 518 VENTSQPGEMQVTIQNLMPATVYIFKVMAQNKHGSGESSAPLRVET 563
           V+N ++      TI  L P   Y   ++A +  G G  S P++V T
Sbjct: 288 VKNDNR----LTTISGLDPNQTYTISILAYSSIGPGPMSHPIQVLT 413
>19544
          Length = 1421

 Score = 63.2 bits (152), Expect = 8e-10,   Method: Compositional matrix adjust.
 Identities = 48/172 (27%), Positives = 79/172 (45%), Gaps = 1/172 (0%)
 Frame = +2

Query: 636 YSFRVVAYNKHGPGVSTQDVAVRTLSDVPSAAPQNLSLEVRNSKSIVIHWQPPSSTTQNG 695
           Y  +V+A N  G G  +    +      P+  P N+    +++ SI + W  P   TQNG
Sbjct: 20  YEVQVLAVNGKGRGPPSTPATIYVGEAAPTEGPSNVQAVNKSASSIQVTWVAPPPETQNG 199

Query: 696 QITGYKIRYRKASRKSDVTETLVTGTQLSQLIEGLDRGTEYNFRVAALTVNGTGPATDWL 755
            ++GYK+ Y K S  ++   T +T  +   L+E L+  T Y   V    + G GP +  +
Sbjct: 200 GLSGYKVLYYKQSSSAEEELTRITA-ETHILLESLETFTVYFIAVQPYNLAGEGPRSALV 376

Query: 756 SAETFESDLDETRVPEVPSSLHVRPL-VTSIVVSWTPPENQNIVVRGYAIGY 806
           SA+T E       VP  P S+    + +  ++V + PP   N  +  Y + Y
Sbjct: 377 SAQTSEG------VPSAPQSIRFTNITMRQLMVHFDPPTTPNGHILLYEMQY 514

 Score = 42.4 bits (98), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 43/148 (29%), Positives = 61/148 (41%), Gaps = 11/148 (7%)
 Frame = +2

Query: 957  YEFSVMVTKGRRSSTWSMTAHGATFELVPTSPPKDVTVVSKEGKPRTIIVNWQ--PPSEA 1014
            YE  V+   G+     S  A     E  PT  P +V  V+K     +I V W   PP   
Sbjct: 20   YEVQVLAVNGKGRGPPSTPATIYVGEAAPTEGPSNVQAVNKSAS--SIQVTWVAPPPETQ 193

Query: 1015 NGKITGY-IIYYSTDVNAEIHDWVIEPVVGNRLTHQ----IQELTLDTPYYFKIQARNSK 1069
            NG ++GY ++YY    +AE            R+T +    ++ L   T Y+  +Q  N  
Sbjct: 194  NGGLSGYKVLYYKQSSSAEEEL--------TRITAETHILLESLETFTVYFIAVQPYNLA 349

Query: 1070 GMGPMSEAVQFRT----PKADSSDKMPN 1093
            G GP S  V  +T    P A  S +  N
Sbjct: 350  GEGPRSALVSAQTSEGVPSAPQSIRFTN 433
>17229
          Length = 487

 Score = 58.5 bits (140), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 42/156 (26%), Positives = 70/156 (44%), Gaps = 11/156 (7%)
 Frame = +1

Query: 515 RERVENTSQPGEMQVTIQNLMPATVYIFKVMAQNKHGSGESSAPLRVETQPEVQLPGPAP 574
           R+ V  + +P      + +L P T+Y  +V A+  HG G  +  ++ +T P   LPG   
Sbjct: 16  RQNVRFSIRPPVNNYRLHDLTPDTIYYIQVSAKTVHGEGPRTPTIQTKTLPF--LPGEPR 189

Query: 575 NIRAYATSPTSITVTWETPLSGNGEIQNYKLYYMEKGTDK--------EQDIDVSS---H 623
            +RA   + T I V W+ P    G+I+ Y +YY++    +        EQ  D  S    
Sbjct: 190 KLRAETINSTGIFVEWDEPKDSRGKIRGYYVYYVKVNGSRDEPPSGLTEQVHDTVSGRVK 369

Query: 624 SYTINGLKKYTEYSFRVVAYNKHGPGVSTQDVAVRT 659
              I GL   + Y  +V  Y + G G  ++ + + T
Sbjct: 370 EAVIIGLDADSRYRVQVAGYTRKGDGRRSKSLVIDT 477

 Score = 39.3 bits (90), Expect = 0.013,   Method: Compositional matrix adjust.
 Identities = 38/149 (25%), Positives = 58/149 (38%), Gaps = 8/149 (5%)
 Frame = +1

Query: 945  SYLVTGLKPNTLYEFSVMVTKGRRSSTWSMTAHGATFELVPTSPPK-DVTVVSKEGKPRT 1003
            +Y +  L P+T+Y   V           + T    T   +P  P K     ++  G    
Sbjct: 55   NYRLHDLTPDTIYYIQVSAKTVHGEGPRTPTIQTKTLPFLPGEPRKLRAETINSTG---- 222

Query: 1004 IIVNWQPPSEANGKITGYIIYYSTDVNAE-------IHDWVIEPVVGNRLTHQIQELTLD 1056
            I V W  P ++ GKI GY +YY   VN         + + V + V G      I  L  D
Sbjct: 223  IFVEWDEPKDSRGKIRGYYVYY-VKVNGSRDEPPSGLTEQVHDTVSGRVKEAVIIGLDAD 399

Query: 1057 TPYYFKIQARNSKGMGPMSEAVQFRTPKA 1085
            + Y  ++     KG G  S+++   T  A
Sbjct: 400  SRYRVQVAGYTRKGDGRRSKSLVIDTKGA 486

 Score = 35.4 bits (80), Expect = 0.19,   Method: Compositional matrix adjust.
 Identities = 33/129 (25%), Positives = 51/129 (39%), Gaps = 13/129 (10%)
 Frame = +1

Query: 734 TEYNFRVAALTVNGTGPATDWLSAETFESDLDETRVPEVPSSLHVRPL-VTSIVVSWTPP 792
           T Y  +V+A TV+G GP T  +  +T         +P  P  L    +  T I V W  P
Sbjct: 85  TIYYIQVSAKTVHGEGPRTPTIQTKTLPF------LPGEPRKLRAETINSTGIFVEWDEP 246

Query: 793 ENQNIVVRGYAIGY------------GIGSPHAQTIKVDYKQRYYTIENLDPSSHYVITL 840
           ++    +RGY + Y            G+      T+    K+    I  LD  S Y + +
Sbjct: 247 KDSRGKIRGYYVYYVKVNGSRDEPPSGLTEQVHDTVSGRVKE--AVIIGLDADSRYRVQV 420

Query: 841 KAFNNVGEG 849
             +   G+G
Sbjct: 421 AGYTRKGDG 447
>06028
          Length = 1358

 Score = 55.1 bits (131), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 62/270 (22%), Positives = 105/270 (38%), Gaps = 34/270 (12%)
 Frame = +1

Query: 193 FVRWEQNRQPLLLDDRIVKLPSG----TLVISNATEGDGGLYRCIVES-GGPPKFSDEAE 247
           +++W +  +P+  D++  ++        L+I N  E D G+Y C+  + G   K S + +
Sbjct: 1   WIQWMKGTEPISNDEKYQQVDQADGYSKLIIHNPVEKDSGVYFCVASNEGAQNKISHQVD 180

Query: 248 LK-------------VLQDPEEIVDLVFLMRPSSMMKVTGQSAVLPCVVSGLPAPV-VRW 293
            K               +DP +     FL    +     G +  +         P+ V+W
Sbjct: 181 FKGRERFTLEKTAGFFHRDPNK---PHFLNPLGNQTVCHGGTVAISAEFMQSSTPIEVKW 351

Query: 294 MKNEEVLDTESSGRLVLLAGGCLEISDVTEDDAGTYFCIADNGNKTVEAQAELTVQV--- 350
           ++N   +D  S           L I +  E+  GTY C+A N    +E+   + V V   
Sbjct: 352 LRNRRPVDGPSVQTFNERGIYTLAIMNAGEEHEGTYTCLASNAFGRIESHVNIDVAVGVE 531

Query: 351 ----PPGFLKQP---ANIYAHESMDIVFECEVTGKPTPTVKWVKNGDVVIPSDYFKIVKE 403
               PP FL +P     I   +   + F   + G P P + ++K    +  SD  ++ KE
Sbjct: 532 KEVRPPLFLSRPETEMKIAVGDPFSLSF--RIAGDPKPRLVFMKGTKDITQSD--RVSKE 699

Query: 404 -----HNLQVLGLVKSDEGFYQCIAENDVG 428
                    V     SD G Y  +A ND G
Sbjct: 700 VSDDYTRFTVQKSQISDSGTYFVVARNDFG 789

 Score = 52.4 bits (124), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 69/285 (24%), Positives = 120/285 (42%), Gaps = 28/285 (9%)
 Frame = +1

Query: 95  IEWKKDGTFLNLESDDRRQLLPDGSLFISNVVHSKHNKPDEGFYQCVATVDNLGTIVSRT 154
           I+W K GT   + +D++ Q +     +   ++H+   K D G Y CVA+  N G     +
Sbjct: 4   IQWMK-GT-EPISNDEKYQQVDQADGYSKLIIHNPVEK-DSGVYFCVAS--NEGAQNKIS 168

Query: 155 AKLTVAGLPRFTSQP-------EPS-----------SVYVGNSAILNCEVNADLVPF-VR 195
            ++   G  RFT +        +P+           +V  G +  ++ E      P  V+
Sbjct: 169 HQVDFKGRERFTLEKTAGFFHRDPNKPHFLNPLGNQTVCHGGTVAISAEFMQSSTPIEVK 348

Query: 196 WEQNRQPL------LLDDRIVKLPSGTLVISNATEGDGGLYRCIVESGGPPKFSDEAELK 249
           W +NR+P+        ++R +     TL I NA E   G Y C+  S    +      + 
Sbjct: 349 WLRNRRPVDGPSVQTFNERGIY----TLAIMNAGEEHEGTYTCLA-SNAFGRIESHVNID 513

Query: 250 VLQDPE-EIVDLVFLMRPSSMMKV-TGQSAVLPCVVSGLPAPVVRWMKN-EEVLDTESSG 306
           V    E E+   +FL RP + MK+  G    L   ++G P P + +MK  +++  ++   
Sbjct: 514 VAVGVEKEVRPPLFLSRPETEMKIAVGDPFSLSFRIAGDPKPRLVFMKGTKDITQSDRVS 693

Query: 307 RLVLLAGGCLEISDVTEDDAGTYFCIADNGNKTVEAQAELTVQVP 351
           + V        +      D+GTYF +A N   T      +T++ P
Sbjct: 694 KEVSDDYTRFTVQKSQISDSGTYFVVARNDFGTDRIFVTITIKTP 828

 Score = 42.4 bits (98), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 49/178 (27%), Positives = 71/178 (39%), Gaps = 23/178 (12%)
 Frame = +1

Query: 291 VRWMKNEEVLDTESSGRLVLLAGGC--LEISDVTEDDAGTYFCIADN---GNK------- 338
           ++WMK  E +  +   + V  A G   L I +  E D+G YFC+A N    NK       
Sbjct: 4   IQWMKGTEPISNDEKYQQVDQADGYSKLIIHNPVEKDSGVYFCVASNEGAQNKISHQVDF 183

Query: 339 ------TVEAQAELTVQVP--PGFLKQPANIYAHESMDIVFECEVTGKPTPT-VKWVKNG 389
                 T+E  A    + P  P FL    N        +    E     TP  VKW++N 
Sbjct: 184 KGRERFTLEKTAGFFHRDPNKPHFLNPLGNQTVCHGGTVAISAEFMQSSTPIEVKWLRNR 363

Query: 390 D-VVIPS-DYFKIVKEHNLQVLGLVKSDEGFYQCIAENDVGNAQAGAQLIILEHDVAI 445
             V  PS   F     + L ++   +  EG Y C+A N  G  ++   +     DVA+
Sbjct: 364 RPVDGPSVQTFNERGIYTLAIMNAGEEHEGTYTCLASNAFGRIESHVNI-----DVAV 522
>20110
          Length = 820

 Score = 46.6 bits (109), Expect(2) = 2e-07,   Method: Compositional matrix adjust.
 Identities = 37/135 (27%), Positives = 59/135 (43%), Gaps = 13/135 (9%)
 Frame = -1

Query: 217 LVISNATEGDGGLYRCIVESGGPPKFSDEAELKVLQDPEEIVDLVFLMRPS-------SM 269
           LV+    E D G+Y C V             +   + P +I +L   + PS       ++
Sbjct: 673 LVVRRLVETDAGIYTCTVRI---------TAVSYEEWPTKIGNLTVQVPPSIKPGDTTAV 521

Query: 270 MKV-TGQSAVLPCVVSGLPAPVVRWMKNEEVLDTESSGRLVLLA-----GGCLEISDVTE 323
           +++  GQ++ L C  SG+PAP + W        T S G  + +         L +++VT 
Sbjct: 520 LQIEQGQNSTLVCAASGIPAPNITW--------TRSDGGFLPIGVAQFRSATLPMNNVTV 365

Query: 324 DDAGTYFCIADNGNK 338
            D G Y C+ADN  K
Sbjct: 364 RDMGVYRCVADNNIK 320

 Score = 27.7 bits (60), Expect(2) = 2e-07,   Method: Composition-based stats.
 Identities = 20/72 (27%), Positives = 31/72 (43%), Gaps = 6/72 (8%)
 Frame = -3

Query: 364 HESMDIVFECEVTGKPTPTVKWVKNGDVVIPSDYFKIVKEHNLQVLGL------VKSDEG 417
           H  +    EC V G P PTV W    ++ I +  F I    +  +  L      +K+ E 
Sbjct: 236 HRPVRANLECIVKGHPEPTVTW----EMAINNGRFPITDHDDFVINKLTTDNQNLKAGEQ 69

Query: 418 FYQCIAENDVGN 429
           +Y    +N +GN
Sbjct: 68  WYTLKVKNVLGN 33

 Score = 45.4 bits (106), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 35/147 (23%), Positives = 61/147 (41%), Gaps = 8/147 (5%)
 Frame = -1

Query: 289 PVVRWMKNEEVLDTESSGRLVLLAGGCLEISDVTEDDAGTYFCIADNGNKTVEAQ----A 344
           P++  ++  EV    S  R   +    L +  + E DAG Y C       + E       
Sbjct: 742 PMIGGLRKYEVQKRLSGDRETYM----LVVRRLVETDAGIYTCTVRITAVSYEEWPTKIG 575

Query: 345 ELTVQVPPGFLKQPANIYA----HESMDIVFECEVTGKPTPTVKWVKNGDVVIPSDYFKI 400
            LTVQVPP    +P +  A     +  +    C  +G P P + W ++    +P    + 
Sbjct: 574 NLTVQVPPSI--KPGDTTAVLQIEQGQNSTLVCAASGIPAPNITWTRSDGGFLPIGVAQF 401

Query: 401 VKEHNLQVLGLVKSDEGFYQCIAENDV 427
            +   L +  +   D G Y+C+A+N++
Sbjct: 400 -RSATLPMNNVTVRDMGVYRCVADNNI 323

 Score = 34.3 bits (77), Expect(2) = 0.003,   Method: Compositional matrix adjust.
 Identities = 21/78 (26%), Positives = 36/78 (46%)
 Frame = -1

Query: 177 GNSAILNCEVNADLVPFVRWEQNRQPLLLDDRIVKLPSGTLVISNATEGDGGLYRCIVES 236
           G ++ L C  +    P + W ++    L    + +  S TL ++N T  D G+YRC+ ++
Sbjct: 505 GQNSTLVCAASGIPAPNITWTRSDGGFLPIG-VAQFRSATLPMNNVTVRDMGVYRCVADN 329

Query: 237 GGPPKFSDEAELKVLQDP 254
              P     AE+ V   P
Sbjct: 328 NIKPPAEHLAEVLVFHAP 275

 Score = 26.2 bits (56), Expect(2) = 0.003,   Method: Composition-based stats.
 Identities = 20/72 (27%), Positives = 32/72 (44%), Gaps = 15/72 (20%)
 Frame = -3

Query: 277 AVLPCVVSGLPAPVVRWM------------KNEEVLDTESSGRLVLLAGG---CLEISDV 321
           A L C+V G P P V W              ++ V++  ++    L AG     L++ +V
Sbjct: 221 ANLECIVKGHPEPTVTWEMAINNGRFPITDHDDFVINKLTTDNQNLKAGEQWYTLKVKNV 42

Query: 322 TEDDAGTYFCIA 333
             +D   Y+CIA
Sbjct: 41  LGNDFTDYYCIA 6

 Score = 36.2 bits (82), Expect = 0.095,   Method: Compositional matrix adjust.
 Identities = 27/80 (33%), Positives = 40/80 (50%), Gaps = 5/80 (6%)
 Frame = -1

Query: 68  VEPVDTLSV----RGSSVILNCSAYSEPSPNIEW-KKDGTFLNLESDDRRQLLPDGSLFI 122
           ++P DT +V    +G +  L C+A   P+PNI W + DG FL +     R      +L +
Sbjct: 547 IKPGDTTAVLQIEQGQNSTLVCAASGIPAPNITWTRSDGGFLPIGVAQFR----SATLPM 380

Query: 123 SNVVHSKHNKPDEGFYQCVA 142
           +NV        D G Y+CVA
Sbjct: 379 NNVTVR-----DMGVYRCVA 335
>08294
          Length = 1849

 Score = 53.1 bits (126), Expect = 9e-07,   Method: Compositional matrix adjust.
 Identities = 33/117 (28%), Positives = 57/117 (48%), Gaps = 2/117 (1%)
 Frame = +2

Query: 138 YQCVATVDNLGTIVSRTAKLTVAGLPRFTSQPEPSSVYVGNSAILNCEVNADLVPFVRWE 197
           Y CVAT    G +++ T  +++   P  T +    +V+ G+SAIL+C       P + W 
Sbjct: 5   YTCVATHPRQG-VINATIHISIVEWPAITVKSNNITVFEGHSAILHCVAKGSPSPDIAWY 181

Query: 198 QNRQPLLLDDRIVKL-PSGTLVISNATEGDGGLYRCIV-ESGGPPKFSDEAELKVLQ 252
           ++ QP+L + R   L  +GT+ I      D G+Y C+   + GP   +    L+ + 
Sbjct: 182 RDSQPILPNARRYTLFKNGTMKIRQVFMEDNGMYACVANNTAGPLAGTSSFALRTMH 352

 Score = 47.4 bits (111), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 22/102 (21%), Positives = 45/102 (44%), Gaps = 2/102 (1%)
 Frame = +2

Query: 329 YFCIADNGNK-TVEAQAELTVQVPPGFLKQPANIYAHESMDIVFECEVTGKPTPTVKWVK 387
           Y C+A +  +  + A   +++   P    +  NI   E    +  C   G P+P + W +
Sbjct: 5   YTCVATHPRQGVINATIHISIVEWPAITVKSNNITVFEGHSAILHCVAKGSPSPDIAWYR 184

Query: 388 NGDVVIP-SDYFKIVKEHNLQVLGLVKSDEGFYQCIAENDVG 428
           +   ++P +  + + K   +++  +   D G Y C+A N  G
Sbjct: 185 DSQPILPNARRYTLFKNGTMKIRQVFMEDNGMYACVANNTAG 310

 Score = 46.6 bits (109), Expect = 8e-05,   Method: Compositional matrix adjust.
 Identities = 21/62 (33%), Positives = 35/62 (56%)
 Frame = +2

Query: 274 GQSAVLPCVVSGLPAPVVRWMKNEEVLDTESSGRLVLLAGGCLEISDVTEDDAGTYFCIA 333
           G SA+L CV  G P+P + W ++ + +   ++ R  L   G ++I  V  +D G Y C+A
Sbjct: 119 GHSAILHCVAKGSPSPDIAWYRDSQPI-LPNARRYTLFKNGTMKIRQVFMEDNGMYACVA 295

Query: 334 DN 335
           +N
Sbjct: 296 NN 301

 Score = 41.6 bits (96), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 24/65 (36%), Positives = 32/65 (49%)
 Frame = +2

Query: 78  GSSVILNCSAYSEPSPNIEWKKDGTFLNLESDDRRQLLPDGSLFISNVVHSKHNKPDEGF 137
           G S IL+C A   PSP+I W +D   + L +  R  L  +G++ I  V        D G 
Sbjct: 119 GHSAILHCVAKGSPSPDIAWYRDSQPI-LPNARRYTLFKNGTMKIRQVFME-----DNGM 280

Query: 138 YQCVA 142
           Y CVA
Sbjct: 281 YACVA 295
>27666
          Length = 873

 Score = 52.8 bits (125), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 51/205 (24%), Positives = 88/205 (42%), Gaps = 29/205 (14%)
 Frame = +1

Query: 252 QDPEEIVDLVFLMRPSSMMKVTGQSAVLPCVVSGLPAPVVRWMKNE--EVLDTESSGRLV 309
           QDPE + D++  ++P       G +A + C V+      V W+  +  E++  + +  L 
Sbjct: 157 QDPEIVDDILPEVQP------VGGTARINCTVANKQTNNVFWIHQDTGELISMDKAVTLQ 318

Query: 310 L--LAGGC-----------------LEISDVTEDDAGTYFCIADNGNKTVEAQAE----L 346
           +  + GG                  L I  + + DAGTY C     N+ + +Q +    L
Sbjct: 319 INQMIGGLRKFEIVQHGPPDRLTFTLVIRRLRQQDAGTYVCQVKIQNENILSQVQKIGTL 498

Query: 347 TVQVPP----GFLKQPANIYAHESMDIVFECEVTGKPTPTVKWVKNGDVVIPSDYFKIVK 402
           TVQVPP    G       I  +++  +V  C  TG P P + W +     +P+ Y +  +
Sbjct: 499 TVQVPPKIRPGETTTLVEIDQNQNSSLV--CSSTGIPAPNITWTRLDGRALPTGYSQF-R 669

Query: 403 EHNLQVLGLVKSDEGFYQCIAENDV 427
              L + G      G Y+C+A N++
Sbjct: 670 GRELPLNGATVDHMGVYRCVANNNI 744

 Score = 37.0 bits (84), Expect = 0.058,   Method: Compositional matrix adjust.
 Identities = 50/193 (25%), Positives = 73/193 (37%), Gaps = 30/193 (15%)
 Frame = +1

Query: 176 VGNSAILNCEVNADLVPFVRW-EQNRQPLLLDDRIVKLP--------------------- 213
           VG +A +NC V       V W  Q+   L+  D+ V L                      
Sbjct: 202 VGGTARINCTVANKQTNNVFWIHQDTGELISMDKAVTLQINQMIGGLRKFEIVQHGPPDR 381

Query: 214 -SGTLVISNATEGDGGLYRCIVESGGPPKFSDEAELKVL--QDPEEIVDLVFLMRPSSMM 270
            + TLVI    + D G Y C V+       S   ++  L  Q P +I       RP    
Sbjct: 382 LTFTLVIRRLRQQDAGTYVCQVKIQNENILSQVQKIGTLTVQVPPKI-------RPGETT 540

Query: 271 KVT----GQSAVLPCVVSGLPAPVVRWMK-NEEVLDTESSGRLVLLAGGCLEISDVTEDD 325
            +      Q++ L C  +G+PAP + W + +   L T  S       G  L ++  T D 
Sbjct: 541 TLVEIDQNQNSSLVCSSTGIPAPNITWTRLDGRALPTGYSQ----FRGRELPLNGATVDH 708

Query: 326 AGTYFCIADNGNK 338
            G Y C+A+N  K
Sbjct: 709 MGVYRCVANNNIK 747

 Score = 30.4 bits (67), Expect = 5.2,   Method: Compositional matrix adjust.
 Identities = 44/208 (21%), Positives = 81/208 (38%), Gaps = 31/208 (14%)
 Frame = +1

Query: 78  GSSVILNCSAYSEPSPNIEW--KKDGTFLNLESDDRRQLL----------------PDGS 119
           G +  +NC+  ++ + N+ W  +  G  ++++     Q+                 PD  
Sbjct: 205 GGTARINCTVANKQTNNVFWIHQDTGELISMDKAVTLQINQMIGGLRKFEIVQHGPPDRL 384

Query: 120 LFISNVVHSKHNKPDEGFYQCVATV--DNLGTIVSRTAKLTVAGLPRFTSQPEPSSVYV- 176
            F   +V  +  + D G Y C   +  +N+ + V +   LTV   P+   +P  ++  V 
Sbjct: 385 TF--TLVIRRLRQQDAGTYVCQVKIQNENILSQVQKIGTLTVQVPPKI--RPGETTTLVE 552

Query: 177 ---GNSAILNCEVNADLVPFVRWEQNRQPLLLDDRIVKLPSG-------TLVISNATEGD 226
                ++ L C       P + W +      LD R   LP+G        L ++ AT   
Sbjct: 553 IDQNQNSSLVCSSTGIPAPNITWTR------LDGR--ALPTGYSQFRGRELPLNGATVDH 708

Query: 227 GGLYRCIVESGGPPKFSDEAELKVLQDP 254
            G+YRC+  +   P      E++V   P
Sbjct: 709 MGVYRCVANNNIKPPDDHLCEVRVFHAP 792
>38127
          Length = 860

 Score = 49.3 bits (116), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 46/149 (30%), Positives = 66/149 (44%), Gaps = 17/149 (11%)
 Frame = -1

Query: 207 DRIVKLPSGTLVISNATEGDGGLYRCIVESGGPPKFSDEAELKVLQDPEEIVDLVFLMRP 266
           +R ++  +GTL I +      G+Y C+ E        +EA +K        VD+ F   P
Sbjct: 827 ERYIQHNNGTLEIQHPRRNFAGMYTCVAEY-------EEAGVK----SSISVDVPFYAHP 681

Query: 267 S------SMMKVTGQSAVLPCVVSGLPAPVVRW-MKNEEVLDTESSGRLVL--------- 310
                  S   V  +S V+ C V G P PVV W M N E++D   S R  L         
Sbjct: 680 KVLPFDKSKNLVQDESLVIECKVLGYPKPVVSWYMDNVEIVDGADS-RYSLKPANSYDGA 504

Query: 311 -LAGGCLEISDVTEDDAGTYFCIADNGNK 338
            + G  L I +V  DDAG Y C+++  +K
Sbjct: 503 SIEGAKLVIEEVQFDDAGEYTCMSNYTDK 417

 Score = 37.0 bits (84), Expect = 0.053,   Method: Compositional matrix adjust.
 Identities = 31/104 (29%), Positives = 49/104 (47%), Gaps = 7/104 (6%)
 Frame = -1

Query: 300 LDTESSGRLVLLAGGCLEISDVTEDDAGTYFCIADNGNKTVEAQAELTVQVP----PGFL 355
           +  +   R +    G LEI     + AG Y C+A+     V  ++ ++V VP    P  L
Sbjct: 845 IKVDGKERYIQHNNGTLEIQHPRRNFAGMYTCVAEYEEAGV--KSSISVDVPFYAHPKVL 672

Query: 356 --KQPANIYAHESMDIVFECEVTGKPTPTVKW-VKNGDVVIPSD 396
              +  N+   ES+  V EC+V G P P V W + N ++V  +D
Sbjct: 671 PFDKSKNLVQDESL--VIECKVLGYPKPVVSWYMDNVEIVDGAD 546
>13135
          Length = 849

 Score = 48.9 bits (115), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 57/177 (32%), Positives = 76/177 (42%), Gaps = 5/177 (2%)
 Frame = -1

Query: 210 VKLPSGT---LVISNATEGDGGLYRCIVESGGPPKFSDEAELKVLQDPEEIVDLVFLMRP 266
           + LPS T   L I N    D G+Y C V+           +L ++Q P+ I DL      
Sbjct: 525 IDLPSPTSWRLRIQNGQVTDEGVYTCQVQLSNQNYAKAFHQLVIIQMPQ-ISDL---DTS 358

Query: 267 SSMMKVTGQSAVLPCVVSGLPAPVVRWMKNEEVLDTESSGRLVLLAGGCLEISDVTEDDA 326
           S + K  GQS VL C  SG P P V+W +    L   S GR  L +   L I  +  + A
Sbjct: 357 SDVSKSEGQSLVLRCHASGRPTPSVKWTRMAGEL-LPSGGREHLESD--LVIPQLKPEHA 187

Query: 327 GTYFCIADNGNKTVEAQAELTVQVPPGFLKQPANIYAHESMDIVFE--CEVTGKPTP 381
           G Y C + N   +      +TV   P  +   AN    ++   V E  C V G PTP
Sbjct: 186 GIYKCSSSNSAGSDFRNIRVTVNFAP--VLSSANTVVQQAQGYVKELVCVVKGYPTP 22

 Score = 43.9 bits (102), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 31/117 (26%), Positives = 53/117 (45%), Gaps = 3/117 (2%)
 Frame = -1

Query: 316 LEISDVTEDDAGTYFCIADNGNKT-VEAQAELTVQVPPGF--LKQPANIYAHESMDIVFE 372
           L I +    D G Y C     N+   +A  +L +   P    L   +++   E   +V  
Sbjct: 495 LRIQNGQVTDEGVYTCQVQLSNQNYAKAFHQLVIIQMPQISDLDTSSDVSKSEGQSLVLR 316

Query: 373 CEVTGKPTPTVKWVKNGDVVIPSDYFKIVKEHNLQVLGLVKSDEGFYQCIAENDVGN 429
           C  +G+PTP+VKW +    ++PS   + + E +L +  L     G Y+C + N  G+
Sbjct: 315 CHASGRPTPSVKWTRMAGELLPSGGREHL-ESDLVIPQLKPEHAGIYKCSSSNSAGS 148

 Score = 32.0 bits (71), Expect = 1.8,   Method: Compositional matrix adjust.
 Identities = 42/167 (25%), Positives = 62/167 (37%), Gaps = 11/167 (6%)
 Frame = -1

Query: 134 DEGFYQCVATVDNLGTIVSRTAKLTVAGLPRFTSQPEPSSVYV--GNSAILNCEVNADLV 191
           DEG Y C   + N         +L +  +P+ +     S V    G S +L C  +    
Sbjct: 468 DEGVYTCQVQLSN-QNYAKAFHQLVIIQMPQISDLDTSSDVSKSEGQSLVLRCHASGRPT 292

Query: 192 PFVRWEQNRQPLLLDDRIVKLPSG-------TLVISNATEGDGGLYRCIVESGGPPKFSD 244
           P V+W +    L        LPSG        LVI        G+Y+C   S      SD
Sbjct: 291 PSVKWTRMAGEL--------LPSGGREHLESDLVIPQLKPEHAGIYKC---SSSNSAGSD 145

Query: 245 EAELKVLQDPEEIVDLVFLMRPSSMMKVTGQSAV--LPCVVSGLPAP 289
              ++V       V+   ++  ++ +    Q  V  L CVV G P P
Sbjct: 144 FRNIRV------TVNFAPVLSSANTVVQQAQGYVKELVCVVKGYPTP 22
>25766
          Length = 469

 Score = 46.6 bits (109), Expect(2) = 2e-05,   Method: Compositional matrix adjust.
 Identities = 28/78 (35%), Positives = 36/78 (46%), Gaps = 1/78 (1%)
 Frame = +1

Query: 314 GCLEISDVTEDDAGTYFC-IADNGNKTVEAQAELTVQVPPGFLKQPANIYAHESMDIVFE 372
           G L+I  VT  DAG Y C I  +   T E  A L +  PP    +  N        + F 
Sbjct: 61  GILQIPRVTAADAGRYRCVITSSEGITSEGFATLRISSPPVVSVKQRNENRQVGSSVKFH 240

Query: 373 CEVTGKPTPTVKWVKNGD 390
           C+V+G P P V+W K  D
Sbjct: 241 CDVSGDPVPQVRWEKKVD 294

 Score = 20.8 bits (42), Expect(2) = 2e-05,   Method: Composition-based stats.
 Identities = 9/23 (39%), Positives = 13/23 (56%)
 Frame = +3

Query: 406 LQVLGLVKSDEGFYQCIAENDVG 428
           L +  + K DEG Y C A ++ G
Sbjct: 330 LTLYNIQKEDEGRYICTASSENG 398

 Score = 38.9 bits (89), Expect = 0.014,   Method: Compositional matrix adjust.
 Identities = 27/87 (31%), Positives = 36/87 (41%)
 Frame = +1

Query: 210 VKLPSGTLVISNATEGDGGLYRCIVESGGPPKFSDEAELKVLQDPEEIVDLVFLMRPSSM 269
           V+   G L I   T  D G YRC++ S         A L++   P      V  ++  + 
Sbjct: 46  VREYDGILQIPRVTAADAGRYRCVITSSEGITSEGFATLRISSPP------VVSVKQRNE 207

Query: 270 MKVTGQSAVLPCVVSGLPAPVVRWMKN 296
            +  G S    C VSG P P VRW K 
Sbjct: 208 NRQVGSSVKFHCDVSGDPVPQVRWEKK 288

 Score = 38.1 bits (87), Expect = 0.029,   Method: Compositional matrix adjust.
 Identities = 27/83 (32%), Positives = 40/83 (48%)
 Frame = +1

Query: 117 DGSLFISNVVHSKHNKPDEGFYQCVATVDNLGTIVSRTAKLTVAGLPRFTSQPEPSSVYV 176
           DG L I  V  +     D G Y+CV T  + G      A L ++  P  + +    +  V
Sbjct: 58  DGILQIPRVTAA-----DAGRYRCVIT-SSEGITSEGFATLRISSPPVVSVKQRNENRQV 219

Query: 177 GNSAILNCEVNADLVPFVRWEQN 199
           G+S   +C+V+ D VP VRWE+ 
Sbjct: 220 GSSVKFHCDVSGDPVPQVRWEKK 288
>11855
          Length = 1574

 Score = 47.8 bits (112), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 48/193 (24%), Positives = 75/193 (38%), Gaps = 41/193 (21%)
 Frame = +1

Query: 285 GLPAPVVRWMKN--------EEVLDTESS-----------GRLVLLAGGCLEISDV-TED 324
           G P P + W+K+         E +D ES+            RL L +       D  T  
Sbjct: 1   GSPVPTIHWLKDGVRLTQSTYETVDDESALYEDLASDPGQPRLRLSSTKSRLYLDCPTSQ 180

Query: 325 DAGTYFCIADNGNK-----------TVEAQAELTVQVPPGFLKQPANIYAH-------ES 366
           D G Y C+A+   K           T     ++T     G   +PA +Y         E+
Sbjct: 181 DEGEYTCVAETPFKRRVQSTIVKVDTRHYSPDVTCMSKRGSRGEPARVYMWTVSRLELET 360

Query: 367 MDIVFECEVTGKPTPTVKWVKNGDVVIP--SDYFKIVKEHNLQVLGLVKSDE-GFYQCIA 423
             +   C  +G P PT+ W    +  +P  S  F I    +L +  +  S+  G Y+C+A
Sbjct: 361 TTVQLFCRASGYPEPTITWYDGRNNSLPDNSGQFSIAVNGDLIIRDISWSENMGVYRCVA 540

Query: 424 ENDVGNAQAGAQL 436
           EN++G+    A L
Sbjct: 541 ENELGSHSVQAFL 579

 Score = 38.1 bits (87), Expect = 0.027,   Method: Compositional matrix adjust.
 Identities = 23/82 (28%), Positives = 41/82 (50%), Gaps = 3/82 (3%)
 Frame = +1

Query: 264 MRPSSMMKVTGQSAVLPCVVSGLPAPVVRWMKNEEVLDTESSGRLVLLAGGCLEISDVT- 322
           M   S +++   +  L C  SG P P + W         ++SG+  +   G L I D++ 
Sbjct: 328 MWTVSRLELETTTVQLFCRASGYPEPTITWYDGRNNSLPDNSGQFSIAVNGDLIIRDISW 507

Query: 323 EDDAGTYFCIADN--GNKTVEA 342
            ++ G Y C+A+N  G+ +V+A
Sbjct: 508 SENMGVYRCVAENELGSHSVQA 573

 Score = 34.3 bits (77), Expect = 0.36,   Method: Compositional matrix adjust.
 Identities = 44/180 (24%), Positives = 69/180 (38%), Gaps = 34/180 (18%)
 Frame = +1

Query: 91  PSPNIEWKKDGTFLNLES----DDRRQLLPDGS-------LFISNVVHSKH----NKPDE 135
           P P I W KDG  L   +    DD   L  D +       L +S+     +       DE
Sbjct: 7   PVPTIHWLKDGVRLTQSTYETVDDESALYEDLASDPGQPRLRLSSTKSRLYLDCPTSQDE 186

Query: 136 GFYQCVATVDNLGTIVSRTAKL-------TVAGLPRFTSQPEPSSVYVGNSAILN----- 183
           G Y CVA       + S   K+        V  + +  S+ EP+ VY+   + L      
Sbjct: 187 GEYTCVAETPFKRRVQSTIVKVDTRHYSPDVTCMSKRGSRGEPARVYMWTVSRLELETTT 366

Query: 184 ----CEVNADLVPFVRWEQNRQPLLLDD--RIVKLPSGTLVISNATEGDG-GLYRCIVES 236
               C  +    P + W   R   L D+  +     +G L+I + +  +  G+YRC+ E+
Sbjct: 367 VQLFCRASGYPEPTITWYDGRNNSLPDNSGQFSIAVNGDLIIRDISWSENMGVYRCVAEN 546
>35419
          Length = 623

 Score = 41.2 bits (95), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 27/83 (32%), Positives = 38/83 (45%), Gaps = 4/83 (4%)
 Frame = -2

Query: 274 GQSAVLPCVVSGLPAPV----VRWMKNEEVLDTESSGRLVLLAGGCLEISDVTEDDAGTY 329
           G  A   C  +  P  V    ++WMK+ + + T        +    L IS     D+GTY
Sbjct: 532 GTDAKFTCSGTTDPEEVHMLKIKWMKDNKEISTVEQRMTTNIQDNSLTISGTIVRDSGTY 353

Query: 330 FCIADNGNKTVEAQAELTVQVPP 352
            CI+ NG  + EA A LTV+  P
Sbjct: 352 TCISTNGLDSAEASAMLTVKDRP 284
>20244
          Length = 452

 Score = 31.6 bits (70), Expect(2) = 0.004,   Method: Compositional matrix adjust.
 Identities = 23/63 (36%), Positives = 27/63 (42%), Gaps = 6/63 (9%)
 Frame = -2

Query: 329 YFCI-ADNG-----NKTVEAQAELTVQVPPGFLKQPANIYAHESMDIVFECEVTGKPTPT 382
           Y C+ A NG      + VE Q  +  +   G    P N Y   S  I F C V G PTP 
Sbjct: 241 YLCLLASNGLGEPVRREVELQVTVNAEAVIGL--DPQNSYTPGS-TIAFNCSVQGYPTPN 71

Query: 383 VKW 385
           V W
Sbjct: 70  VTW 62

 Score = 28.5 bits (62), Expect(2) = 0.004,   Method: Composition-based stats.
 Identities = 13/35 (37%), Positives = 18/35 (51%)
 Frame = -1

Query: 272 VTGQSAVLPCVVSGLPAPVVRWMKNEEVLDTESSG 306
           + G  AVL C  +G PAP + W     V+DT  + 
Sbjct: 404 LNGGIAVLRCFATGNPAPNITWSLKNVVIDTTKAA 300
>36498
          Length = 478

 Score = 34.7 bits (78), Expect(2) = 0.028,   Method: Composition-based stats.
 Identities = 20/74 (27%), Positives = 28/74 (37%), Gaps = 4/74 (5%)
 Frame = +3

Query: 316 LEISDVTEDDAGTYFCIADNGNKTVEAQAELTVQ----VPPGFLKQPANIYAHESMDIVF 371
           L    V+E DAG Y C+A N     E   +LTV      P   +  P      +   +  
Sbjct: 231 LRFDPVSEGDAGRYVCVARNERGITEENVDLTVTRTGVAPQVNIDGPGRQMLVDGQSVEL 410

Query: 372 ECEVTGKPTPTVKW 385
            C   G   P ++W
Sbjct: 411 SCSARGLRNPLIRW 452

 Score = 22.3 bits (46), Expect(2) = 0.028,   Method: Composition-based stats.
 Identities = 9/31 (29%), Positives = 14/31 (45%)
 Frame = +1

Query: 267 SSMMKVTGQSAVLPCVVSGLPAPVVRWMKNE 297
           + +  + G    + CV  G P P V W + E
Sbjct: 76  TRITALVGDRVDIECVAEGDPTPTVFWRRIE 168

 Score = 35.8 bits (81), Expect = 0.15,   Method: Composition-based stats.
 Identities = 24/75 (32%), Positives = 33/75 (44%), Gaps = 2/75 (2%)
 Frame = +3

Query: 223 TEGDGGLYRCIV--ESGGPPKFSDEAELKVLQDPEEIVDLVFLMRPSSMMKVTGQSAVLP 280
           +EGD G Y C+   E G   +  D    +    P+  +D      P   M V GQS  L 
Sbjct: 249 SEGDAGRYVCVARNERGITEENVDLTVTRTGVAPQVNID-----GPGRQMLVDGQSVELS 413

Query: 281 CVVSGLPAPVVRWMK 295
           C   GL  P++RW +
Sbjct: 414 CSARGLRNPLIRWRR 458

 Score = 31.6 bits (70), Expect = 2.2,   Method: Composition-based stats.
 Identities = 20/52 (38%), Positives = 22/52 (42%), Gaps = 1/52 (1%)
 Frame = +1

Query: 335 NGNKTVEAQAELTVQVPPGFLKQPAN-IYAHESMDIVFECEVTGKPTPTVKW 385
           N   TV   A L +Q PP     P   I A     +  EC   G PTPTV W
Sbjct: 1   NAAGTVTLTASLVIQGPPTVTVTPGTRITALVGDRVDIECVAEGDPTPTVFW 156
>18345
          Length = 461

 Score = 37.7 bits (86), Expect = 0.034,   Method: Compositional matrix adjust.
 Identities = 25/64 (39%), Positives = 32/64 (50%), Gaps = 1/64 (1%)
 Frame = +1

Query: 274 GQSAVLPCVVSGLPAPVVRWMK-NEEVLDTESSGRLVLLAGGCLEISDVTEDDAGTYFCI 332
           G +A L C V+G+P+P V W K N   LD +     V   G  L + +VT      Y C 
Sbjct: 157 GDTATLVCNVTGVPSPDVTWYKRNTRQLDAQKE--RVGSTGPVLVMYNVTRHCDDIYECY 330

Query: 333 ADNG 336
           ADNG
Sbjct: 331 ADNG 342

 Score = 33.9 bits (76), Expect = 0.54,   Method: Compositional matrix adjust.
 Identities = 25/88 (28%), Positives = 38/88 (43%), Gaps = 1/88 (1%)
 Frame = +1

Query: 169 PEPSSVYVGNSAILNCEVNADLVPFVRW-EQNRQPLLLDDRIVKLPSGTLVISNATEGDG 227
           P+  S+  G++A L C V     P V W ++N + L      V      LV+ N T    
Sbjct: 133 PDRVSLKEGDTATLVCNVTGVPSPDVTWYKRNTRQLDAQKERVGSTGPVLVMYNVTRHCD 312

Query: 228 GLYRCIVESGGPPKFSDEAELKVLQDPE 255
            +Y C  ++G PP  +    + V   PE
Sbjct: 313 DIYECYADNGVPPAVTKAIRVTVDYAPE 396
>32888
          Length = 418

 Score = 34.3 bits (77), Expect(2) = 0.040,   Method: Compositional matrix adjust.
 Identities = 12/36 (33%), Positives = 18/36 (50%)
 Frame = -3

Query: 361 IYAHESMDIVFECEVTGKPTPTVKWVKNGDVVIPSD 396
           +   E   +  +C   GKP+P V W KNG ++   D
Sbjct: 248 VLEDEGQTVRLDCRAKGKPSPKVTWYKNGHIITNGD 141

 Score = 21.9 bits (45), Expect(2) = 0.040,   Method: Composition-based stats.
 Identities = 9/27 (33%), Positives = 14/27 (51%)
 Frame = -2

Query: 402 KEHNLQVLGLVKSDEGFYQCIAENDVG 428
           +++ L +  L   D+G Y CI  N  G
Sbjct: 126 QKYKLTIKSLGAEDKGNYTCIVSNTEG 46

 Score = 29.3 bits (64), Expect(2) = 1.2,   Method: Compositional matrix adjust.
 Identities = 11/32 (34%), Positives = 18/32 (56%)
 Frame = -3

Query: 269 MMKVTGQSAVLPCVVSGLPAPVVRWMKNEEVL 300
           +++  GQ+  L C   G P+P V W KN  ++
Sbjct: 248 VLEDEGQTVRLDCRAKGKPSPKVTWYKNGHII 153

 Score = 21.9 bits (45), Expect(2) = 1.2,   Method: Composition-based stats.
 Identities = 10/35 (28%), Positives = 16/35 (45%)
 Frame = -2

Query: 316 LEISDVTEDDAGTYFCIADNGNKTVEAQAELTVQV 350
           L I  +  +D G Y CI  N    ++    + V+V
Sbjct: 114 LTIKSLGAEDKGNYTCIVSNTEGQIDWTFYVDVEV 10

 Score = 31.6 bits (70), Expect = 2.4,   Method: Compositional matrix adjust.
 Identities = 15/41 (36%), Positives = 23/41 (56%)
 Frame = -3

Query: 74  LSVRGSSVILNCSAYSEPSPNIEWKKDGTFLNLESDDRRQL 114
           L   G +V L+C A  +PSP + W K+G  +    DDR ++
Sbjct: 245 LEDEGQTVRLDCRAKGKPSPKVTWYKNGHII-TNGDDRVEI 126
>11788
          Length = 569

 Score = 35.4 bits (80), Expect = 0.16,   Method: Compositional matrix adjust.
 Identities = 27/124 (21%), Positives = 49/124 (39%)
 Frame = +1

Query: 629 GLKKYTEYSFRVVAYNKHGPGVSTQDVAVRTLSDVPSAAPQNLSLEVRNSKSIVIHWQPP 688
           GL    +Y   V  +N  G    +    + T  + P   P+ + +     +S+ + W+  
Sbjct: 133 GLFANDDYWVTVQVFNTAGLSRPSGCNYMNTNYEAPLHYPEYVQVSSHGPESVQVFWRGV 312

Query: 689 SSTTQNGQITGYKIRYRKASRKSDVTETLVTGTQLSQLIEGLDRGTEYNFRVAALTVNGT 748
           S+      ++GYKI Y   +      +  V     S ++ G++R   Y  RV   +  G 
Sbjct: 313 STIQIESPVSGYKIWYWPYTDNIRTAKVAVFPKVFSGVLHGIERDKIYKLRVLGTSDGGD 492

Query: 749 GPAT 752
           G  T
Sbjct: 493 GKKT 504
>37675
          Length = 741

 Score = 34.7 bits (78), Expect = 0.29,   Method: Compositional matrix adjust.
 Identities = 23/81 (28%), Positives = 39/81 (48%), Gaps = 3/81 (3%)
 Frame = +2

Query: 346 LTVQVPPGFLKQPANIYAHESMDIVFECEVTGKPTPTVKWVKNGDVVIPSD--YFKIVKE 403
           L VQ+PP     P ++     ++   +C   G P PT+ W+ N +V I  D  ++ +   
Sbjct: 53  LKVQMPPVVKVSPHSLIYPARLNAKMKCHAEGVPKPTISWLFN-NVPISEDPQHYDLESA 229

Query: 404 HNLQVL-GLVKSDEGFYQCIA 423
           + L V+      D G Y+C+A
Sbjct: 230 NELLVVYNAGDQDTGAYKCVA 292

 Score = 32.7 bits (73), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 17/73 (23%), Positives = 32/73 (43%)
 Frame = +2

Query: 261 VFLMRPSSMMKVTGQSAVLPCVVSGLPAPVVRWMKNEEVLDTESSGRLVLLAGGCLEISD 320
           V  + P S++     +A + C   G+P P + W+ N   +  +     +  A   L + +
Sbjct: 74  VVKVSPHSLIYPARLNAKMKCHAEGVPKPTISWLFNNVPISEDPQHYDLESANELLVVYN 253

Query: 321 VTEDDAGTYFCIA 333
             + D G Y C+A
Sbjct: 254 AGDQDTGAYKCVA 292
>11732
          Length = 640

 Score = 34.3 bits (77), Expect = 0.36,   Method: Compositional matrix adjust.
 Identities = 25/79 (31%), Positives = 36/79 (45%), Gaps = 2/79 (2%)
 Frame = +2

Query: 312 AGGCLEISDVTEDDAGTYFCIADNGNKTVEAQAELTVQVPPGFLKQPANIYAHESMDIVF 371
           A G L  SD++ DDAG Y C + +G + V     L V + P   +   N+     +D + 
Sbjct: 38  ALGYLSFSDLSMDDAGLYQCKSTSGMEQVIRNITLFVVLEPQIKR---NMSTFTMLDGIA 208

Query: 372 E--CEVTGKPTPTVKWVKN 388
           E  C   G P PT  +  N
Sbjct: 209 EAVCVAEGDPAPTFLFRGN 265
>17530
          Length = 503

 Score = 33.5 bits (75), Expect = 0.66,   Method: Compositional matrix adjust.
 Identities = 20/52 (38%), Positives = 26/52 (50%), Gaps = 4/52 (7%)
 Frame = +2

Query: 342 AQAELTVQVPPGFLKQPANIYA---HESMDIVFECEVTG-KPTPTVKWVKNG 389
           A A LTV +PPG     ++I      E   + F C  +G  P PT+ W KNG
Sbjct: 26  ASANLTVLLPPGPPSITSDITGDVFEEGQRVRFTCSSSGGNPPPTITWTKNG 181
>29881
          Length = 416

 Score = 33.5 bits (75), Expect = 0.75,   Method: Compositional matrix adjust.
 Identities = 24/64 (37%), Positives = 31/64 (48%)
 Frame = -3

Query: 272 VTGQSAVLPCVVSGLPAPVVRWMKNEEVLDTESSGRLVLLAGGCLEISDVTEDDAGTYFC 331
           V G S+V    VSG  A V  W K+ ++       R+  L    L +S+V E DAG Y C
Sbjct: 405 VKGDSSV---SVSGAQADVTMWRKDGDMFTQGPRKRM--LVNNYLMVSNVVETDAGQYTC 241

Query: 332 IADN 335
            A N
Sbjct: 240 AARN 229

 Score = 32.0 bits (71), Expect = 2.1,   Method: Composition-based stats.
 Identities = 16/54 (29%), Positives = 26/54 (48%)
 Frame = -3

Query: 375 VTGKPTPTVKWVKNGDVVIPSDYFKIVKEHNLQVLGLVKSDEGFYQCIAENDVG 428
           V+G       W K+GD+       +++  + L V  +V++D G Y C A N  G
Sbjct: 381 VSGAQADVTMWRKDGDMFTQGPRKRMLVNNYLMVSNVVETDAGQYTCAARNSEG 220
>34369
          Length = 300

 Score = 33.1 bits (74), Expect = 0.78,   Method: Compositional matrix adjust.
 Identities = 23/75 (30%), Positives = 35/75 (46%), Gaps = 3/75 (4%)
 Frame = +3

Query: 480 LVSTRFIKLTWRTPASDPHGDNLTYSVFYTK---EGVARERVENTSQPGEMQVTIQNLMP 536
            + +R + + W T   D +    +Y+V   +   +   RE V   S     Q+TI NL P
Sbjct: 12  FIESREVTVYWTTSRDDNNSPITSYTVQVNECENDTTVRELVTGGST---FQITIPNLTP 182

Query: 537 ATVYIFKVMAQNKHG 551
            T Y  +V+AQN  G
Sbjct: 183 YTCYAIQVLAQNSVG 227
>04057
          Length = 1327

 Score = 32.7 bits (73), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 26/87 (29%), Positives = 34/87 (39%), Gaps = 17/87 (19%)
 Frame = +1

Query: 1006 VNWQPPSEANGKITGYIIYYSTDVNAEIHDWVIEP----------------VVGNRLTHQ 1049
            ++W+PP    GKIT Y +Y +   NA        P                VV N   H 
Sbjct: 97   LSWEPPQNTAGKITEYSVYLAVR-NANTEPKPGTPSQLAFVRVFCGPSPSCVVTNASLHS 273

Query: 1050 IQ-ELTLDTPYYFKIQARNSKGMGPMS 1075
               + T      F+I ARN KG GP +
Sbjct: 274  AHIDYTTKPAIIFRIAARNEKGYGPAT 354
>33163
          Length = 444

 Score = 31.6 bits (70), Expect = 2.4,   Method: Compositional matrix adjust.
 Identities = 15/53 (28%), Positives = 26/53 (49%), Gaps = 4/53 (7%)
 Frame = +2

Query: 1004 IIVNWQPPSEANGKITGYIIYYST-DVNAE---IHDWVIEPVVGNRLTHQIQE 1052
            ++V W PP   NG +T Y +Y+   ++N E     D+   P++  +   Q  E
Sbjct: 5    LLVTWDPPKIPNGNVTHYWVYWQVQELNWEPFDQRDYCKNPIIATKEKKQTSE 163
>29932
          Length = 748

 Score = 30.8 bits (68), Expect = 4.3,   Method: Compositional matrix adjust.
 Identities = 17/50 (34%), Positives = 24/50 (48%)
 Frame = +3

Query: 309 VLLAGGCLEISDVTEDDAGTYFCIADNGNKTVEAQAELTVQVPPGFLKQP 358
           V + G  L    +T  DAG Y C A N   T    A++ V+ P  + +QP
Sbjct: 231 VHIDGQILRFVAITPADAGGYSCTASNKYGTNSKTAQVVVRPPTFYTQQP 380
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|160707879|ref|NP_062318.2| formin 2 [Mus musculus]
         (1578 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

11636                                                                  71   3e-12
27291                                                                  70   7e-12
06790                                                                  70   1e-11
06817                                                                  59   2e-08
35444                                                                  52   2e-06
11680                                                                  31   3.2  
>11636
          Length = 819

 Score = 71.2 bits (173), Expect = 3e-12,   Method: Compositional matrix adjust.
 Identities = 72/261 (27%), Positives = 115/261 (44%), Gaps = 8/261 (3%)
 Frame = +1

Query: 1286 SLDKPEQFLYELSLIPNFSERVFCILFQSTFSESICSIRRKLELLQKLCETLKNGPGVMQ 1345
            ++ + ++FL+E+S I ++ ER+  + F+  F E     ++K+E + + C+ +     + Q
Sbjct: 97   NMARADRFLFEMSKITHYEERLKALYFKKKFQERRHDCKQKIEAVHEACKEVFRSRKLKQ 276

Query: 1346 VLGLVLAFGNYMNAGNKTRGQADGFGLDILPKLKDVKSSDNSR-SLLSYIVSYYLRNFDE 1404
            +L LVLA GNYMN G   RG A GF    L K+ D +SS + + +LL Y+V    + F  
Sbjct: 277  LLELVLACGNYMNRGQ--RGNALGFKPTSLNKMLDTRSSVSKQVTLLHYVVETLEKKF-A 447

Query: 1405 DAGKEQCVFPLAEPQELFQASQMKFEDFQXXXXXXXXXXXACEAEAGKVYQVSSAEHMQP 1464
            D  K +   P        +A+++ F+D +             E E           H   
Sbjct: 448  DVMKLEDDLPHVR-----EAAKVNFKDLEKEIXALKKGLQGIEKEVDFFKSKLDNPH-DR 609

Query: 1465 FKENMEQFISQAKIDQESQEAALTETH-------KCFLETTAYYFMKPKLGEKEVSPNVF 1517
            F   M+ F + A       E A TE         K F E +           K+V P+ F
Sbjct: 610  FVNVMQDFCTVASYSFAEVEDAFTEMRNKYDSVLKAFCEDS-----------KQVQPDAF 756

Query: 1518 FSVWHEFSSDFKDAWKKENKL 1538
            F  +  F S F +A  +  KL
Sbjct: 757  FGCFDSFLSSFGEAKTENEKL 819
>27291
          Length = 435

 Score = 70.1 bits (170), Expect = 7e-12,   Method: Compositional matrix adjust.
 Identities = 40/114 (35%), Positives = 63/114 (55%)
 Frame = -2

Query: 1281 KENAKSLDKPEQFLYELSLIPNFSERVFCILFQSTFSESICSIRRKLELLQKLCETLKNG 1340
            K+    L +PEQF   +S I    +R+  +LFQ  F E +  I+  L    + CE +   
Sbjct: 401  KDQYDELAEPEQFAIVMSSIKKVHQRLESMLFQMRFQEMVDDIKPDLVSATEACEEVMKS 222

Query: 1341 PGVMQVLGLVLAFGNYMNAGNKTRGQADGFGLDILPKLKDVKSSDNSRSLLSYI 1394
                Q+L LVL  GNY+N+G++   Q+ GF +  LPKL++ KS D S ++L ++
Sbjct: 221  ERFKQLLELVLLMGNYLNSGSRN-AQSIGFDISFLPKLENTKSQDGSITMLHFL 63
>06790
          Length = 620

 Score = 69.7 bits (169), Expect = 1e-11,   Method: Composition-based stats.
 Identities = 49/190 (25%), Positives = 92/190 (48%)
 Frame = -3

Query: 1206 KTKAKQVVKLLSNKRSQAVGILMSSLHLDMKDIQHAVVNLDNSVVDLETLQALYENRAQS 1265
            K   K+ V LL   R + V I    + +  ++I  A+  LD   + L+ +  L       
Sbjct: 597  KKHKKECVSLLEPNRLRNVAITRRKIEMTNEEIVRAINGLDLKRLSLDIVDILQTVLPND 418

Query: 1266 DELEKIEKHSRSSKDKENAKSLDKPEQFLYELSLIPNFSERVFCILFQSTFSESICSIRR 1325
             E +    + R   D+   +SL   ++F+ ++  +   S ++  + F   + +++  ++ 
Sbjct: 417  QETKAFRLYER---DRRPVESLGDEDKFMIQMVKVERLSHKLTIMSFIGNYHDNLHHLQP 247

Query: 1326 KLELLQKLCETLKNGPGVMQVLGLVLAFGNYMNAGNKTRGQADGFGLDILPKLKDVKSSD 1385
            ++  +     +LKN   V +++ ++LA GNYMN+ NK RG A GF L  L  L D KS D
Sbjct: 246  QINAIIAASMSLKNSHKVKKMMEIILALGNYMNS-NK-RGAAYGFKLQSLDMLVDTKSGD 73

Query: 1386 NSRSLLSYIV 1395
               +L+ ++V
Sbjct: 72   KKTTLMHFLV 43
>06817
          Length = 2234

 Score = 58.9 bits (141), Expect = 2e-08,   Method: Composition-based stats.
 Identities = 72/349 (20%), Positives = 144/349 (41%), Gaps = 13/349 (3%)
 Frame = +1

Query: 1213 VKLLSNKRSQAV-GILMSSLHLDMKDIQHAVVNLDNSVVDLETLQALYENRAQSDELEKI 1271
            + + +++ ++A+ G+ +  L LD+ DI                LQ +  N  ++   +  
Sbjct: 7    IDMTNDEMARAINGLDLKQLSLDLVDI----------------LQTILPNEQETKAFKMY 138

Query: 1272 EKHSRSSKDKENAKSLDKPEQFLYELSLIPNFSERVFCILFQSTFSESICSIRRKLELLQ 1331
            E+      D+   ++L   ++F+  +  +   S ++  + F   + +++  ++ ++  + 
Sbjct: 139  ER------DRRPLEALGDEDKFMLHMVKVERLSHKLTIMSFIGNYYDNLHQLQPQVNAII 300

Query: 1332 KLCETLKNGPGVMQVLGLVLAFGNYMNAGNKTRGQADGFGLDILPKLKDVKSSDNSRSLL 1391
                +LKN   V +++ ++LA GNYMN+ NK RG   GF L  L  L D KS D   +L+
Sbjct: 301  AASMSLKNSQKVKKLMEIILAMGNYMNS-NK-RGAVYGFKLQSLDMLVDTKSGDRKTTLM 474

Query: 1392 SYIVSYYLRNFDEDAGKEQCVFPLAEPQELFQASQMKFEDFQXXXXXXXXXXXACEAEAG 1451
             ++V      F               P+ L   S+++F D               E E G
Sbjct: 475  HFLVQTVHDKF---------------PELLTFDSELRFLDKAALVSMENITTDVHELEKG 609

Query: 1452 KVYQVSSAEH------------MQPFKENMEQFISQAKIDQESQEAALTETHKCFLETTA 1499
               +++  E+            ++ F  N E+   +  +D ++ + + T+  + + E   
Sbjct: 610  --MELTKKEYAARKDSRDCPVILKDFLANAEERFKKLLVDVKTAQDSYTKVVEYYGENA- 780

Query: 1500 YYFMKPKLGEKEVSPNVFFSVWHEFSSDFKDAWKKENKLILQERVKEAE 1548
                      + VSP  FF+    F + FK A      L+  ER K+ E
Sbjct: 781  ----------RSVSPANFFAQIVRFVNSFKQA------LLDNERRKKLE 879
>35444
          Length = 506

 Score = 52.0 bits (123), Expect = 2e-06,   Method: Composition-based stats.
 Identities = 32/59 (54%), Positives = 37/59 (62%)
 Frame = -1

Query: 1346 VLGLVLAFGNYMNAGNKTRGQADGFGLDILPKLKDVKSSDNSRSLLSYIVSYYLRNFDE 1404
            VL +VLAFGNY+N+ NK RG A GF L  L  L D KS+D   SLL YIV+     F E
Sbjct: 398  VLEIVLAFGNYLNS-NK-RGPAYGFKLQSLDTLIDTKSTDKRSSLLHYIVATIRAKFPE 228
>11680
          Length = 576

 Score = 31.2 bits (69), Expect = 3.2,   Method: Composition-based stats.
 Identities = 13/22 (59%), Positives = 13/22 (59%)
 Frame = +1

Query: 856 LGMAIPPPPCLSDITVPALPSP 877
           LG   PPPPC  D T PAL  P
Sbjct: 232 LGAGRPPPPCRQDNTXPALECP 297
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|21312970|ref|NP_080433.1| PAP associated domain
containing 1 [Mus musculus]
         (585 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

26590                                                                  70   3e-12
11079                                                                  38   0.011
34248                                                                  34   0.21 
19228                                                                  30   2.4  
35107                                                                  28   9.1  
>26590
          Length = 736

 Score = 69.7 bits (169), Expect = 3e-12,   Method: Compositional matrix adjust.
 Identities = 45/188 (23%), Positives = 86/188 (45%), Gaps = 2/188 (1%)
 Frame = -3

Query: 187 ESIEEQLNTLLKAFQLTEENIRLRHLTCSLIEDIAAAYFPSCVIRPFGSSVNTFGKLGCD 246
           E I E +         +EE++R + +  + +  I    FP C +   GSS++ FG    D
Sbjct: 521 ERITEAIVEYYNTSHQSEEDLRHKIVLSNCLYAIVRGIFPGCRLFIVGSSLSGFGTRTSD 342

Query: 247 LDMFLDLDETGKLDVHKNTGNFFMEFQVKNVPSERIATQKILSVIGECLDNFGPGCVGVQ 306
           +D+ L + +   +D                   ++     IL+ I + L N    C  V+
Sbjct: 341 MDLCLLVTQDKFID-------------------QKYEAVHILNAIHKSLRN----CTFVK 231

Query: 307 --KILNARCPLVRFSHQGSGFQCDLTANNSIALKSSELLYIYGSLDSRVRALVFSVRCWA 364
             +++ A+ P+++F+      +CDL  NN + ++++ LL  Y   D+RV  L+  ++ WA
Sbjct: 230 SSQVIKAKVPILKFTDSTKNIECDLNINNGVGIRNTHLLKYYCLADNRVAPLMLFIKFWA 51

Query: 365 RAHSLTSS 372
           R H +  +
Sbjct: 50  RFHDINDA 27
>11079
          Length = 879

 Score = 38.1 bits (87), Expect = 0.011,   Method: Compositional matrix adjust.
 Identities = 19/74 (25%), Positives = 39/74 (52%)
 Frame = -2

Query: 322 GSGFQCDLTANNSIALKSSELLYIYGSLDSRVRALVFSVRCWARAHSLTSSIPGAWITNF 381
            +G    +  ++  A+ +S LL +Y   D R+++L   +R WA+   L     G  +  +
Sbjct: 860 STGLHIVVVIDHQSAVLTSHLLQVYTLCDPRLKSLAVMLRSWAKICRLDCQEKGT-LPAY 684

Query: 382 SLTVMVIFFLQRRS 395
           +  ++V++FLQ+ S
Sbjct: 683 AYNLLVVYFLQQTS 642
>34248
          Length = 931

 Score = 33.9 bits (76), Expect = 0.21,   Method: Compositional matrix adjust.
 Identities = 25/75 (33%), Positives = 37/75 (49%), Gaps = 1/75 (1%)
 Frame = +3

Query: 127 LQNGTHTPTQSTEAAIPFKSRFLNLRLKNPSSQ-VSGQPFVQTTNQSPPSSKKLFELLSY 185
           + N  H   + + AA P    F + R+KN  S  +SG+P   +  Q   +SKK    LS+
Sbjct: 573 IHNPAHITIKVSLAAQPHGCCFFDTRVKNILSL*LSGRPV*ASIVQDQNTSKKRVYPLSF 752

Query: 186 AESIEEQLNTLLKAF 200
             S+   LNT+L  F
Sbjct: 753 PASLSPALNTILCNF 797
>19228
          Length = 462

 Score = 30.0 bits (66), Expect = 2.4,   Method: Composition-based stats.
 Identities = 16/39 (41%), Positives = 22/39 (56%), Gaps = 1/39 (2%)
 Frame = +3

Query: 289 SVIGECLDNFGPGCVGVQKILNARCPLV-RFSHQGSGFQ 326
           SV+G+ LD  GPGC+G + +    C LV R    G  F+
Sbjct: 318 SVLGQWLDGVGPGCLGFRLV----CGLVWRLGESGFSFR 422
>35107
          Length = 679

 Score = 28.1 bits (61), Expect = 9.1,   Method: Compositional matrix adjust.
 Identities = 26/103 (25%), Positives = 47/103 (45%)
 Frame = +2

Query: 335 IALKSSELLYIYGSLDSRVRALVFSVRCWARAHSLTSSIPGAWITNFSLTVMVIFFLQRR 394
           I L     L +  SLD     +VFSVR   ++    S++ G   T  SL   ++F L   
Sbjct: 272 ITLGGDAELELVDSLDPFSEGIVFSVRPPKKSWKNISNLSGGEKTLSSLA--LVFALHHY 445

Query: 395 SPPILPTLDSLKSIADAEDRCILEGNNCTFVQDVNKIQPSGNT 437
            P  L  +D + +  D ++  I+      +++D  K++ S ++
Sbjct: 446 KPTPLYVMDEIDAALDFKNVSIV----ANYIKDGQKMRSSSSS 562
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|34915988|ref|NP_033898.1| basigin isoform 1 [Mus
musculus]
         (389 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

38127                                                                  69   3e-12
08294                                                                  36   0.031
13135                                                                  36   0.033
25766                                                                  32   0.059
27666                                                                  34   0.090
25455                                                                  32   0.61 
00299                                                                  31   0.79 
20110                                                                  31   0.87 
13662                                                                  28   5.2  
20244                                                                  28   5.3  
32888                                                                  28   6.5  
>38127
          Length = 860

 Score = 68.9 bits (167), Expect = 3e-12,   Method: Compositional matrix adjust.
 Identities = 62/198 (31%), Positives = 95/198 (47%), Gaps = 9/198 (4%)
 Frame = -1

Query: 198 SGEYSCIFLPEPVG-RSEINVEGP----PRIKVGKKSEHSSEGELAKLVCKSDASYPPIT 252
           +G Y+C+   E  G +S I+V+ P    P++    KS++  + E   + CK      P+ 
Sbjct: 767 AGMYTCVAEYEEAGVKSSISVDVPFYAHPKVLPFDKSKNLVQDESLVIECKVLGYPKPVV 588

Query: 253 DWFWFKTSDTGEEEAITNSTEANGKYVVVSTPEKSQLTISNLDVNVDPGTYVC--NATNA 310
            W+          ++  +   AN  Y   S  E ++L I  +  + D G Y C  N T+ 
Sbjct: 587 SWYMDNVEIVDGADSRYSLKPANS-YDGASI-EGAKLVIEEVQFD-DAGEYTCMSNYTDK 417

Query: 311 --QGTTRETISLRVRSRMAALWPFLGIVAEVLVLVTIIFIYEKRRKPDQTLDEDDPGAAP 368
             Q  + + I +RV++      PFLGIVAEV+VL  IIFIYEK+R  D  ++ED      
Sbjct: 416 WPQFNSTQVILVRVKTSWRPCGPFLGIVAEVVVLCAIIFIYEKKRSKDAPVEED------ 255

Query: 369 LKGSGTHMNDKDKNVRQR 386
           +    T    K + VRQR
Sbjct: 254 VNQETTSEEKKAEGVRQR 201
>08294
          Length = 1849

 Score = 35.8 bits (81), Expect = 0.031,   Method: Compositional matrix adjust.
 Identities = 23/78 (29%), Positives = 34/78 (43%)
 Frame = +2

Query: 35  WAGGSVVLHCEAVGSPIPEIQWWFEGNAPNDSCSQLWDGARLDRVHIHAAYRQHAASSLS 94
           + G S +LHC A GSP P+I W+       DS   L +  R         Y      ++ 
Sbjct: 113 FEGHSAILHCVAKGSPSPDIAWY------RDSQPILPNARR---------YTLFKNGTMK 247

Query: 95  VDGLTAEDTGTYECRASS 112
           +  +  ED G Y C A++
Sbjct: 248 IRQVFMEDNGMYACVANN 301
>13135
          Length = 849

 Score = 35.8 bits (81), Expect = 0.033,   Method: Compositional matrix adjust.
 Identities = 21/76 (27%), Positives = 32/76 (42%)
 Frame = -1

Query: 37  GGSVVLHCEAVGSPIPEIQWWFEGNAPNDSCSQLWDGARLDRVHIHAAYRQHAASSLSVD 96
           G S+VL C A G P P ++W                  R+    + +  R+H  S L + 
Sbjct: 336 GQSLVLRCHASGRPTPSVKW-----------------TRMAGELLPSGGREHLESDLVIP 208

Query: 97  GLTAEDTGTYECRASS 112
            L  E  G Y+C +S+
Sbjct: 207 QLKPEHAGIYKCSSSN 160
>25766
          Length = 469

 Score = 32.0 bits (71), Expect(2) = 0.059,   Method: Compositional matrix adjust.
 Identities = 10/26 (38%), Positives = 17/26 (65%)
 Frame = +1

Query: 31  SQERWAGGSVVLHCEAVGSPIPEIQW 56
           ++ R  G SV  HC+  G P+P+++W
Sbjct: 202 NENRQVGSSVKFHCDVSGDPVPQVRW 279

 Score = 21.6 bits (44), Expect(2) = 0.059,   Method: Compositional matrix adjust.
 Identities = 13/43 (30%), Positives = 20/43 (46%)
 Frame = +3

Query: 93  LSVDGLTAEDTGTYECRASSDPDRNHLTRPPRVKWVRAQASVV 135
           L++  +  ED G Y C ASS+   +      RV  +R   S +
Sbjct: 330 LTLYNIQKEDEGRYICTASSENGVDRDYSNLRVSDIRNIGSSI 458
>27666
          Length = 873

 Score = 34.3 bits (77), Expect = 0.090,   Method: Compositional matrix adjust.
 Identities = 22/80 (27%), Positives = 31/80 (38%), Gaps = 2/80 (2%)
 Frame = +1

Query: 42  LHCEAVGSPIPEIQWWFEGNAPNDSCSQLWDGARLDRVHIHAAYRQHAASSLSVDGLTAE 101
           L C + G P P I W                  RLD   +   Y Q     L ++G T +
Sbjct: 577 LVCSSTGIPAPNITW-----------------TRLDGRALPTGYSQFRGRELPLNGATVD 705

Query: 102 DTGTYECRASSD--PDRNHL 119
             G Y C A+++  P  +HL
Sbjct: 706 HMGVYRCVANNNIKPPDDHL 765
>25455
          Length = 444

 Score = 31.6 bits (70), Expect = 0.61,   Method: Compositional matrix adjust.
 Identities = 32/122 (26%), Positives = 52/122 (42%), Gaps = 4/122 (3%)
 Frame = +1

Query: 209 PVGRSEINVEGPPRIKVGKKSEHSSEGELAKLVCKSDASYPPITDWFW--FKTSDTGEEE 266
           P+    + V+  P   V  +      GE A++ C + A   P+T+WF    + SD  E +
Sbjct: 43  PLREMRVVVQSAPSWVVAPQVTEVEVGETAEITCNATAIPDPVTNWFVNGREISDVVEHD 222

Query: 267 AITNSTEANGKYVVVSTPEKSQLTISNLDVNVDPGTYV--CNATNAQGTTRETISLRVRS 324
               S    G++ + S     +L + N+ +    G  V  CN TN  G     +SL V +
Sbjct: 223 VRFQS----GRFDLTS----DRLILRNVTIE---GRMVVQCNVTNRYGHLWADVSLNVLT 369

Query: 325 RM 326
            M
Sbjct: 370 PM 375
>00299
          Length = 1481

 Score = 31.2 bits (69), Expect = 0.79,   Method: Compositional matrix adjust.
 Identities = 36/162 (22%), Positives = 54/162 (33%), Gaps = 27/162 (16%)
 Frame = +1

Query: 207 PEPVGRSEINVEGPPRIKVGKKSEH-----SSEGELAKLVCKSDAS-------------- 247
           P P   S++  +GPP IK  K+        S   EL KL    DA+              
Sbjct: 211 PPPTAISKLKYQGPPHIKKDKRQSSSRFNVSKNRELQKLALLKDATPAEREELFVQKLRQ 390

Query: 248 --------YPPITDWFWFKTSDTGEEEAITNSTEANGKYVVVSTPEKSQLTISNLDVNVD 299
                     P++D  W +       E +   T+  G       PE   +   NL   + 
Sbjct: 391 CIVLFDFVQDPLSDLKWKEVKRAALNEMVEYVTQNRGVITEAIYPEAITMFAVNLFRTLP 570

Query: 300 PGTYVCNATNAQGTTRETISLRVRSRMAALWPFLGIVAEVLV 341
           P +   N + A+    E         + A WP L +V E  +
Sbjct: 571 PSS---NPSGAEFDPEED-----EPTLEAAWPHLQLVYEFFL 672
>20110
          Length = 820

 Score = 30.8 bits (68), Expect = 0.87,   Method: Compositional matrix adjust.
 Identities = 22/85 (25%), Positives = 32/85 (37%), Gaps = 2/85 (2%)
 Frame = -1

Query: 37  GGSVVLHCEAVGSPIPEIQWWFEGNAPNDSCSQLWDGARLDRVHIHAAYRQHAASSLSVD 96
           G +  L C A G P P I W                  R D   +     Q  +++L ++
Sbjct: 505 GQNSTLVCAASGIPAPNITW-----------------TRSDGGFLPIGVAQFRSATLPMN 377

Query: 97  GLTAEDTGTYECRASSD--PDRNHL 119
            +T  D G Y C A ++  P   HL
Sbjct: 376 NVTVRDMGVYRCVADNNIKPPAEHL 302
>13662
          Length = 654

 Score = 28.5 bits (62), Expect = 5.2,   Method: Compositional matrix adjust.
 Identities = 22/88 (25%), Positives = 42/88 (47%), Gaps = 6/88 (6%)
 Frame = +1

Query: 128 VRAQASVVVLEPGT---IQTSVQEVNSKTQLTCSLN---SSGVDIVGHRWMRGGKVLQED 181
           +R  A++ V  PG    ++T V+ +NS   ++ ++N      ++I+ +    GG++  E 
Sbjct: 160 LRVDANISVNRPGDPWGVRTEVKNINSIRNISKAINFEIQRQINILEN----GGQIENET 327

Query: 182 TLPDLHTKYIVDADDRSGEYSCIFLPEP 209
              D  T   V+  D+       F+PEP
Sbjct: 328 RSFDAETDETVEMRDKEKLLDYRFMPEP 411
>20244
          Length = 452

 Score = 28.5 bits (62), Expect = 5.3,   Method: Compositional matrix adjust.
 Identities = 11/20 (55%), Positives = 12/20 (60%)
 Frame = -1

Query: 37  GGSVVLHCEAVGSPIPEIQW 56
           GG  VL C A G+P P I W
Sbjct: 398 GGIAVLRCFATGNPAPNITW 339
>32888
          Length = 418

 Score = 28.1 bits (61), Expect = 6.5,   Method: Compositional matrix adjust.
 Identities = 16/73 (21%), Positives = 33/73 (45%), Gaps = 11/73 (15%)
 Frame = -3

Query: 37  GGSVVLHCEAVGSPIPEIQWWFEGNAPNDS-----------CSQLWDGARLDRVHIHAAY 85
           G +V L C A G P P++ W+  G+   +             S++W+    + +H+ +A 
Sbjct: 233 GQTVRLDCRAKGKPSPKVTWYKNGHIITNGDDRVEIKSTS*PSKVWERRTRETIHVSSAT 54

Query: 86  RQHAASSLSVDGL 98
           ++   +  S+  L
Sbjct: 53  QRDKLTGPSMSML 15
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|19526956|ref|NP_598510.1| RIKEN cDNA 2900064A13 [Mus
musculus]
         (241 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

20243                                                                  47   4e-12
19607                                                                  30   1.0  
08363                                                                  28   4.5  
>20243
          Length = 624

 Score = 46.6 bits (109), Expect(2) = 4e-12,   Method: Compositional matrix adjust.
 Identities = 20/44 (45%), Positives = 30/44 (68%)
 Frame = +2

Query: 116 KMRARYVNYIKTSEVVRLPYPLQMKSSGPPSYFIKRESWGWTDF 159
           KMRAR VN ++ +++  + YPL+ +  G P+YF +RE W  TDF
Sbjct: 2   KMRARKVNRLQPTKLQTVHYPLEFREMGKPTYFQQREQWRVTDF 133

 Score = 40.8 bits (94), Expect(2) = 4e-12,   Method: Compositional matrix adjust.
 Identities = 17/35 (48%), Positives = 25/35 (71%)
 Frame = +1

Query: 183 NTSDPDMRREMEQSMNMLNSNHELPDVSEFMTRLF 217
           NT+DP+ R+EMEQ M+ LN    +PD++E  T +F
Sbjct: 202 NTADPETRKEMEQQMSSLNQKPNMPDMAEMFTNMF 306
>19607
          Length = 581

 Score = 29.6 bits (65), Expect = 1.0,   Method: Compositional matrix adjust.
 Identities = 10/27 (37%), Positives = 19/27 (70%)
 Frame = -1

Query: 84  VVHDIPSGSYVVEVISPAYKFDPVRVD 110
           V+ ++P G+++ E    A KFDP+R++
Sbjct: 299 VIQEMPMGAFLDEFFCVAQKFDPLRLN 219
>08363
          Length = 1878

 Score = 27.7 bits (60), Expect = 4.5,   Method: Compositional matrix adjust.
 Identities = 12/23 (52%), Positives = 16/23 (69%)
 Frame = -1

Query: 60  WISAARVLVDGEEHVGFLKTDGS 82
           W+SAA  +V+GE  VGF +T G 
Sbjct: 117 WVSAAERVVEGEGSVGFGETGGG 49
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|16905129|ref|NP_473436.1| neuronal calcium-binding
protein 2 [Mus musculus]
         (389 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

18979                                                                  68   5e-12
02929                                                                  35   0.062
18571                                                                  31   0.91 
10577                                                                  30   1.2  
26849                                                                  30   1.3  
17484                                                                  28   7.7  
06705                                                                  28   8.2  
>18979
          Length = 639

 Score = 68.2 bits (165), Expect = 5e-12,   Method: Compositional matrix adjust.
 Identities = 42/137 (30%), Positives = 69/137 (50%), Gaps = 3/137 (2%)
 Frame = -2

Query: 250 GLEGQISRLAELIGRLESKTLSFDLQQRLSDEE---GTNMHLQLVRQEMAVCPEQLSEFL 306
            +  Q+ RLA ++ RLE+K ++F       DEE   G +  + LV++E  V   ++ EF 
Sbjct: 611 AISAQVERLASMLDRLETK-VNF---HHFRDEEVIEGEDQIVLLVQREFNVKEGKVEEFR 444

Query: 307 DSLRQYLRSTAEERNCFHVAAVRMADGLTFVIYEFWETEEEWKRHLQSPVCKAFRHVKVD 366
             LR Y+  T     C +++   + +  TF IYE W TE+E+ ++  S   K       D
Sbjct: 443 ALLRGYVDVTQGFHGCLNISVRDLRETNTFSIYEVWRTEQEYIQNCDSAATKTLVDSSAD 264

Query: 367 TLSQPEALSQISVPAAW 383
            L  PE +  + +PA+W
Sbjct: 263 LLVSPETVHSMKIPASW 213
>02929
          Length = 1353

 Score = 34.7 bits (78), Expect = 0.062,   Method: Compositional matrix adjust.
 Identities = 20/63 (31%), Positives = 31/63 (49%), Gaps = 6/63 (9%)
 Frame = +2

Query: 68  ILDIFRRADKNDDGKLSLEEFQLFFADGVL------NEKELEGLFHTIDSDNTNHVDTKE 121
           + D FRR DK+ DG L+ EE    F +G++      N  EL  +F   D +    ++ K+
Sbjct: 182 VTDFFRRQDKDGDGFLTEEE----FVNGMMQSRFPTNRTELNAVFDIFDREKRGLIEYKD 349

Query: 122 LCD 124
             D
Sbjct: 350 FVD 358
>18571
          Length = 821

 Score = 30.8 bits (68), Expect = 0.91,   Method: Compositional matrix adjust.
 Identities = 14/17 (82%), Positives = 15/17 (88%)
 Frame = -2

Query: 72  FRRADKNDDGKLSLEEF 88
           FR+ DKN DGKLSLEEF
Sbjct: 811 FRQMDKNLDGKLSLEEF 761
>10577
          Length = 876

 Score = 30.4 bits (67), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 15/50 (30%), Positives = 27/50 (54%), Gaps = 4/50 (8%)
 Frame = +2

Query: 115 NHVDTKELCDYFVEHMGDYEDVLASLET----LNHSVLKAMGYTKKVYEG 160
           +HV  +E+ D     +G YED+L +++      N  V ++ G TK + +G
Sbjct: 341 DHVTNQEVQDKIKSAIGPYEDLLTTVKKRKLQWNGHVTRSTGLTKTILQG 490
>26849
          Length = 649

 Score = 30.4 bits (67), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 18/53 (33%), Positives = 28/53 (52%), Gaps = 2/53 (3%)
 Frame = +2

Query: 72  FRRADKNDDGKLSLEEFQLFFADG--VLNEKELEGLFHTIDSDNTNHVDTKEL 122
           FR  DK+    LSLEEF+    D    +NE ++E +F+  D+D    ++  E 
Sbjct: 185 FRVMDKDGSKVLSLEEFKKGILDMHIDINEADIEDMFYRFDNDGNGTINMTEF 343
>17484
          Length = 471

 Score = 27.7 bits (60), Expect = 7.7,   Method: Compositional matrix adjust.
 Identities = 15/50 (30%), Positives = 28/50 (56%), Gaps = 2/50 (4%)
 Frame = -1

Query: 76  DKNDDGKLSLEEFQ--LFFADGVLNEKELEGLFHTIDSDNTNHVDTKELC 123
           D++ +GK++  EF+  +      L+EKELE +    D+D +  ++ K  C
Sbjct: 462 DQDGNGKITRNEFRSVVRMLGHSLSEKELEEMMQAADTDASGAIELKSSC 313
>06705
          Length = 1176

 Score = 27.7 bits (60), Expect = 8.2,   Method: Compositional matrix adjust.
 Identities = 14/40 (35%), Positives = 25/40 (62%)
 Frame = +1

Query: 121 ELCDYFVEHMGDYEDVLASLETLNHSVLKAMGYTKKVYEG 160
           ELC YFV+H  D ++    L+  N +V++A+ + K ++ G
Sbjct: 136 ELCRYFVDH--DPQE----LKPFNDAVMQAVDFQKSLFNG 237
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|124301217|ref|NP_112151.2| VPS10 domain receptor
protein SORCS 2 [Mus musculus]
         (1159 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

31914                                                                  70   6e-12
19139                                                                  37   0.050
>31914
          Length = 457

 Score = 69.7 bits (169), Expect = 6e-12,   Method: Composition-based stats.
 Identities = 45/153 (29%), Positives = 77/153 (50%), Gaps = 3/153 (1%)
 Frame = +3

Query: 462 DGKVTTVITYNKGRDWDYLRPPSTDMNGKPTNCQPPDCYLHLHLRWADNPYVSG-TVHTK 520
           D  + +VIT++ G +W  L  P    +G     +  DC L +H  ++ +  +      + 
Sbjct: 15  DNSIHSVITFDLGGEWKTLPKP----DGVSCKDEGKDCSLQIHNEYSIHRGIKAFRPLSA 182

Query: 521 DTAPGLIMGAGNLGSQLVEYKEEMYITSDCGHTWRQVFEEEHHVLYLDHGGVIAAI--KD 578
           + APGLI+   +    L     +++++S+ G++WR+  +  H  +  D GG+I AI  KD
Sbjct: 183 EDAPGLIIVNAHAAKNLQTTXPDVFVSSNGGYSWRKALDGPHAYVIADSGGLIVAISIKD 362

Query: 579 TSIPLKILKFSVDEGHTWSTHNFTSTSVFVDGL 611
            S P ++ KFS DEG  W  + FT   +   GL
Sbjct: 363 -SYPNEV-KFSTDEGRCWHVYQFTKDKIHHTGL 455
>19139
          Length = 514

 Score = 37.0 bits (84), Expect = 0.050,   Method: Compositional matrix adjust.
 Identities = 21/59 (35%), Positives = 30/59 (50%), Gaps = 1/59 (1%)
 Frame = +2

Query: 705 DFLCDYGFERSSSSESTANKCSANFWFNPLSPPEDCVLG-QTYTSSLGYRKVVSNVCEG 762
           D+ CDYGF R S  E    KC  +  +  +   + C  G +    S GYRK+  +VC+G
Sbjct: 5   DYECDYGFSRQSGQE----KCDKDPNYRNMPEIDICFRGHEEKVISEGYRKLPGDVCDG 169
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|169790954|ref|NP_082993.2| alsin isoform 1 [Mus
musculus]
         (1651 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

13543                                                                  70   6e-12
24275                                                                  69   1e-11
02938                                                                  66   9e-11
31725                                                                  60   1e-08
26574                                                                  58   4e-08
27967                                                                  55   2e-07
07985                                                                  43   8e-04
03352                                                                  38   0.027
12101                                                                  38   0.034
20162                                                                  37   0.069
32825                                                                  35   0.34 
39525                                                                  34   0.47 
07231                                                                  32   2.4  
17531                                                                  31   3.5  
33425                                                                  31   4.6  
20193                                                                  30   9.8  
>13543
          Length = 821

 Score = 70.5 bits (171), Expect = 6e-12,   Method: Composition-based stats.
 Identities = 60/211 (28%), Positives = 85/211 (40%), Gaps = 3/211 (1%)
 Frame = -1

Query: 1043 YDGRWLSGKPHGRGVLKWPDGKMYSGMFRNGLEDGYG--EYRIPNKALNKEDHYVGHWKE 1100
            Y+G W +GK HG G L   DG  Y G F NG  +G+G   + + N        Y G +  
Sbjct: 815  YEGEWKNGKKHGHGKLTMKDGTYYEGQFVNGEINGHGFKFFSVSNY------KYTGQFLN 654

Query: 1101 GKMCGQGVYSYASGEVFEGCFQDNMRHGHGLLRSGKLTSSSPSMFIGQWVMDKKAGYGVF 1160
            G+M G GV  Y    ++E                            GQWV  +K    VF
Sbjct: 653  GEMHGHGVMQYRDESIYE----------------------------GQWVKKQKTRLLVF 558

Query: 1161 DDITRGEKYM-GMWQDDVCQGNGVVVTQFGLYYEGNFHLNKMMGNGVLLSEDDTIYEGEF 1219
                R  +YM G ++     G G      G  YEG + +++  G+G L   D T Y G+F
Sbjct: 557  CG-HRARQYMKGHFKHINKNGEGSQTYDNGDRYEGYWVMDQRHGHGELFCADGTYYVGQF 381

Query: 1220 SDDWTLSGKGTLTMPHGDYIEGYFSGEWGSG 1250
            + D    G+G +    G      + G+W  G
Sbjct: 380  AHD-MYHGEGKMQHASG----MLYVGQWLHG 303

 Score = 56.6 bits (135), Expect = 9e-08,   Method: Composition-based stats.
 Identities = 38/142 (26%), Positives = 71/142 (50%), Gaps = 1/142 (0%)
 Frame = -1

Query: 1033 YKDTRLKDATYDGRWLSGKPHGRGVLKWPDGKMYSGMFRNGLEDGYGEYRIPNKALNKED 1092
            +K   + +  Y G++L+G+ HG GV+++ D  +Y G +    +      R+     ++  
Sbjct: 704  FKFFSVSNYKYTGQFLNGEMHGHGVMQYRDESIYEGQWVKKQKT-----RLLVFCGHRAR 540

Query: 1093 HYV-GHWKEGKMCGQGVYSYASGEVFEGCFQDNMRHGHGLLRSGKLTSSSPSMFIGQWVM 1151
             Y+ GH+K     G+G  +Y +G+ +EG +  + RHGH     G+L  +  + ++GQ+  
Sbjct: 539  QYMKGHFKHINKNGEGSQTYDNGDRYEGYWVMDQRHGH-----GELFCADGTYYVGQFAH 375

Query: 1152 DKKAGYGVFDDITRGEKYMGMW 1173
            D   G G     + G  Y+G W
Sbjct: 374  DMYHGEGKMQHAS-GMLYVGQW 312

 Score = 36.6 bits (83), Expect = 0.092,   Method: Composition-based stats.
 Identities = 29/104 (27%), Positives = 45/104 (43%), Gaps = 28/104 (26%)
 Frame = -1

Query: 1168 KYMGMWQDDVCQGNGVVVTQFGLYYEGNF-----------------------HLN-KMMG 1203
            +Y G W++    G+G +  + G YYEG F                        LN +M G
Sbjct: 818  RYEGEWKNGKKHGHGKLTMKDGTYYEGQFVNGEINGHGFKFFSVSNYKYTGQFLNGEMHG 639

Query: 1204 NGVLLSEDDTIYEGEFSDDWTLSGKGTLTMPHG----DYIEGYF 1243
            +GV+   D++IYEG+    W    K  L +  G     Y++G+F
Sbjct: 638  HGVMQYRDESIYEGQ----WVKKQKTRLLVFCGHRARQYMKGHF 519
>24275
          Length = 2220

 Score = 69.3 bits (168), Expect = 1e-11,   Method: Composition-based stats.
 Identities = 42/125 (33%), Positives = 63/125 (50%)
 Frame = -3

Query: 1052 PHGRGVLKWPDGKMYSGMFRNGLEDGYGEYRIPNKALNKEDHYVGHWKEGKMCGQGVYSY 1111
            P GRG  K    K YSG ++  L  GYG      +   ++++Y G W  GK  G G   Y
Sbjct: 2215 PDGRGGFK----KEYSGGWKGDLRHGYG-----TEFYTEDEYYEGEWYAGKRSGWGRMYY 2063

Query: 1112 ASGEVFEGCFQDNMRHGHGLLRSGKLTSSSPSMFIGQWVMDKKAGYGVFDDITRGEKYMG 1171
              G ++EG + D+ R+G G+LR       + + + G W  DKK G G F  +  G+ + G
Sbjct: 2062 KDGNIYEGEWYDDQRNGQGMLR-----LVNENRYEGSWKDDKKNGPGKFYYLDSGQVFEG 1898

Query: 1172 MWQDD 1176
            +W +D
Sbjct: 1897 VWVND 1883

 Score = 57.8 bits (138), Expect = 3e-08,   Method: Composition-based stats.
 Identities = 33/108 (30%), Positives = 55/108 (50%), Gaps = 1/108 (0%)
 Frame = -3

Query: 1039 KDATYDGRWLSGKPHGRGVLKWPDGKMYSGMFRNGLEDGYGEYRIPNKALNKEDHYVGHW 1098
            +D  Y+G W +GK  G G + + DG +Y G + +   +G G  R+ N     E+ Y G W
Sbjct: 2128 EDEYYEGEWYAGKRSGWGRMYYKDGNIYEGEWYDDQRNGQGMLRLVN-----ENRYEGSW 1964

Query: 1099 KEGKMCGQGVYSYA-SGEVFEGCFQDNMRHGHGLLRSGKLTSSSPSMF 1145
            K+ K  G G + Y  SG+VFEG + ++      +   G+  +  P+ +
Sbjct: 1963 KDDKKNGPGKFYYLDSGQVFEGVWVNDTPKCGTMRDFGRDNAPEPTQY 1820

 Score = 45.1 bits (105), Expect = 2e-04,   Method: Composition-based stats.
 Identities = 27/84 (32%), Positives = 44/84 (52%)
 Frame = -3

Query: 1167 EKYMGMWQDDVCQGNGVVVTQFGLYYEGNFHLNKMMGNGVLLSEDDTIYEGEFSDDWTLS 1226
            ++Y G W+ D+  G G        YYEG ++  K  G G +  +D  IYEGE+ DD   +
Sbjct: 2191 KEYSGGWKGDLRHGYGTEFYTEDEYYEGEWYAGKRSGWGRMYYKDGNIYEGEWYDD-QRN 2015

Query: 1227 GKGTLTMPHGDYIEGYFSGEWGSG 1250
            G+G L + + +  EG +  +  +G
Sbjct: 2014 GQGMLRLVNENRYEGSWKDDKKNG 1943

 Score = 39.3 bits (90), Expect = 0.015,   Method: Composition-based stats.
 Identities = 25/78 (32%), Positives = 38/78 (48%)
 Frame = -3

Query: 1145 FIGQWVMDKKAGYGVFDDITRGEKYMGMWQDDVCQGNGVVVTQFGLYYEGNFHLNKMMGN 1204
            + G W  D + GYG  +  T  E Y G W      G G +  + G  YEG ++ ++  G 
Sbjct: 2185 YSGGWKGDLRHGYGT-EFYTEDEYYEGEWYAGKRSGWGRMYYKDGNIYEGEWYDDQRNGQ 2009

Query: 1205 GVLLSEDDTIYEGEFSDD 1222
            G+L   ++  YEG + DD
Sbjct: 2008 GMLRLVNENRYEGSWKDD 1955
>02938
          Length = 1718

 Score = 66.2 bits (160), Expect = 9e-11,   Method: Compositional matrix adjust.
 Identities = 55/171 (32%), Positives = 85/171 (49%), Gaps = 8/171 (4%)
 Frame = +3

Query: 47  ALGVRHGVLLTEDGEVYSFGTLP----WKSESAEICPSSPLLESALVGHHVITVATGSFH 102
           A G  H + LTEDG V+ +G          E ++I    P+     VG  V  +A+G +H
Sbjct: 288 AAGCDHSLALTEDGRVFVWGGNGEGQLGMGEDSDI----PVPRQLDVGQSVACIASGYYH 455

Query: 103 SGAVTESGVVYMWGENAAGQCAV-ANQQYVPEPSPV-SISDSETSPSLAVRILQLACGEE 160
           S  VTESG +Y +GE+  G+  +  +      P  V +I+D         ++  ++CG  
Sbjct: 456 SALVTESGELYTFGESDGGKLGLNGDTDECKTPQQVMAIND---------KVKSVSCGGS 608

Query: 161 HTLALSLSREIWAWGTGC--QLGLITTTFPVTKPQKVEHLAGRVVLQVACG 209
           HT+AL+   E++A+G G   QLGL  +T     P  ++ L  +V  QV CG
Sbjct: 609 HTVALTEKGEVYAFGEGSSGQLGLGVSTLESESPSLLK-LPFKVA-QVCCG 755

 Score = 62.0 bits (149), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 56/192 (29%), Positives = 89/192 (46%), Gaps = 14/192 (7%)
 Frame = +3

Query: 40  GKTVLQAALGVRHGVLLTEDGEVYSF-----GTLPWKSESAEICPSSPLLESALVGHHVI 94
           G++V   A G  H  L+TE GE+Y+F     G L    ++ E      ++    +   V 
Sbjct: 417 GQSVACIASGYYHSALVTESGELYTFGESDGGKLGLNGDTDECKTPQQVM---AINDKVK 587

Query: 95  TVATGSFHSGAVTESGVVYMWGENAAGQCAVANQQYVPEPSPVSISDSETSPS---LAVR 151
           +V+ G  H+ A+TE G VY +GE ++GQ  +           VS  +SE SPS   L  +
Sbjct: 588 SVSCGGSHTVALTEKGEVYAFGEGSSGQLGLG----------VSTLESE-SPSLLKLPFK 734

Query: 152 ILQLACGEEHTLALSLSREIWAWGTG--CQLGL----ITTTFPVTKPQKVEHLAGRVVLQ 205
           + Q+ CGE  T  +S   +++ +G G   +L L     +  F  T   KV+      V +
Sbjct: 735 VAQVCCGENFTTVVSERGQLYTFGDGRHGKLALGQESFSNQFVCT---KVDRFLKFNVKK 905

Query: 206 VACGAFHSLALV 217
            ACG  H + + 
Sbjct: 906 AACGGCHLIVMA 941

 Score = 50.1 bits (118), Expect = 7e-06,   Method: Compositional matrix adjust.
 Identities = 45/160 (28%), Positives = 68/160 (42%), Gaps = 4/160 (2%)
 Frame = +3

Query: 487 PRLLRKAARVKTRTVVLTPTYSGEADALLPSLRTEVWTWGKGKEGQLGHGDVLPRLQPLC 546
           P  ++     K R V       G +  ++ +    ++ +G   EGQLG   V     P  
Sbjct: 87  PSCVKSLKHEKARLVAC-----GRSHTIVATESGNIYAFGANGEGQLGVEGVTETNLPKQ 251

Query: 547 VKCLDGKEVIHLEAGGSHSLALTAKSQVYSWGSNTFGQLGHSEFPTTVPRLSKVSSENGV 606
           V  L       L AG  HSLALT   +V+ WG N  GQLG  E  + +P   ++     V
Sbjct: 252 VDSLQATPWKMLAAGCDHSLALTEDGRVFVWGGNGEGQLGMGE-DSDIPVPRQLDVGQSV 428

Query: 607 WSVAAGQDYSLFLVDTEDFQPGLYYSGRQDRAE----GDT 642
             +A+G  +S  + ++ +    LY  G  D  +    GDT
Sbjct: 429 ACIASGYYHSALVTESGE----LYTFGESDGGKLGLNGDT 536

 Score = 47.4 bits (111), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 37/109 (33%), Positives = 52/109 (47%), Gaps = 6/109 (5%)
 Frame = +3

Query: 522 VWTWGKGKEGQLGHGDVLPRLQPLCVKCLDGKEVIHLEAGGSHSLALTAKSQVYSWGSNT 581
           V+ +G    GQLG G      +P CVK L  ++   +  G SH++  T    +Y++G+N 
Sbjct: 21  VFMFGPNDYGQLGIGAQKVANRPSCVKSLKHEKARLVACGRSHTIVATESGNIYAFGANG 200

Query: 582 FGQLG-----HSEFPTTVPRLSKVSSENGVWSV-AAGQDYSLFLVDTED 624
            GQLG      +  P  V  L         W + AAG D+SL L  TED
Sbjct: 201 EGQLGVEGVTETNLPKQVDSLQATP-----WKMLAAGCDHSLAL--TED 326

 Score = 46.2 bits (108), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 34/102 (33%), Positives = 57/102 (55%), Gaps = 3/102 (2%)
 Frame = +3

Query: 521 EVWTWGKGKEGQLG-HGDVLPRLQPLCVKCLDGKEVIHLEAGGSHSLALTAKSQVYSWGS 579
           E++T+G+   G+LG +GD      P  V  ++ K V  +  GGSH++ALT K +VY++G 
Sbjct: 480 ELYTFGESDGGKLGLNGDTDECKTPQQVMAINDK-VKSVSCGGSHTVALTEKGEVYAFGE 656

Query: 580 NTFGQLGH--SEFPTTVPRLSKVSSENGVWSVAAGQDYSLFL 619
            + GQLG   S   +  P L K+  +  V  V  G++++  +
Sbjct: 657 GSSGQLGLGVSTLESESPSLLKLPFK--VAQVCCGENFTTVV 776

 Score = 45.8 bits (107), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 36/111 (32%), Positives = 53/111 (47%), Gaps = 2/111 (1%)
 Frame = +3

Query: 110 GVVYMWGENAAGQCAVANQQYVPEPSPVSISDSETSPSLAVRILQLACGEEHTLALSLSR 169
           G V+M+G N  GQ  +  Q+    PS V     E +     R++  ACG  HT+  + S 
Sbjct: 15  GRVFMFGPNDYGQLGIGAQKVANRPSCVKSLKHEKA-----RLV--ACGRSHTIVATESG 173

Query: 170 EIWAWGTG--CQLGLITTTFPVTKPQKVEHLAGRVVLQVACGAFHSLALVQ 218
            I+A+G     QLG+   T     P++V+ L       +A G  HSLAL +
Sbjct: 174 NIYAFGANGEGQLGVEGVT-ETNLPKQVDSLQATPWKMLAAGCDHSLALTE 323

 Score = 44.7 bits (104), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 49/164 (29%), Positives = 76/164 (46%), Gaps = 6/164 (3%)
 Frame = +3

Query: 60  GEVYSFGTLPWK--SESAEICPSSPLLESALVGHHVITVATGSFHSGAVTESGVVYMWGE 117
           G V+ FG   +      A+   + P    +L       VA G  H+   TESG +Y +G 
Sbjct: 15  GRVFMFGPNDYGQLGIGAQKVANRPSCVKSLKHEKARLVACGRSHTIVATESGNIYAFGA 194

Query: 118 NAAGQCAVANQQYVPEPS-PVSISDSETSPSLAVRILQLACGEEHTLALSLSREIWAWGT 176
           N  GQ  V   + V E + P  +   + +P        LA G +H+LAL+    ++ WG 
Sbjct: 195 NGEGQLGV---EGVTETNLPKQVDSLQATP-----WKMLAAGCDHSLALTEDGRVFVWGG 350

Query: 177 G--CQLGL-ITTTFPVTKPQKVEHLAGRVVLQVACGAFHSLALV 217
               QLG+   +  PV  P++++   G+ V  +A G +HS ALV
Sbjct: 351 NGEGQLGMGEDSDIPV--PRQLD--VGQSVACIASGYYHS-ALV 467
>31725
          Length = 1230

 Score = 59.7 bits (143), Expect = 1e-08,   Method: Composition-based stats.
 Identities = 30/96 (31%), Positives = 46/96 (47%), Gaps = 10/96 (10%)
 Frame = -2

Query: 1039 KDATYDGRWLSGKPHGRGVLKW----------PDGKMYSGMFRNGLEDGYGEYRIPNKAL 1088
            ++  Y+G+W +G  HG G   W          P   MY G F NGL  G+G +   N A 
Sbjct: 1211 RNQIYNGQWENGIQHGMGQHIWLLSRVPGSQYPMRNMYDGEFVNGLRHGFGTFHYANGA- 1035

Query: 1089 NKEDHYVGHWKEGKMCGQGVYSYASGEVFEGCFQDN 1124
                 Y G+WK     G+G + + +G ++EG F+ +
Sbjct: 1034 ----SYSGYWKNNMKHGKGKFMFKNGRIYEGMFEHD 939

 Score = 54.7 bits (130), Expect = 3e-07,   Method: Composition-based stats.
 Identities = 26/88 (29%), Positives = 50/88 (56%), Gaps = 8/88 (9%)
 Frame = -2

Query: 1058 LKWPD-GKMYSGMFRNGLEDGYGEY-----RIPNKALNKEDHYVGHWKEGKMCGQGVYSY 1111
            +KW D  ++Y+G + NG++ G G++     R+P       + Y G +  G   G G + Y
Sbjct: 1226 MKWIDRNQIYNGQWENGIQHGMGQHIWLLSRVPGSQYPMRNMYDGEFVNGLRHGFGTFHY 1047

Query: 1112 ASGEVFEGCFQDNMRHGHG--LLRSGKL 1137
            A+G  + G +++NM+HG G  + ++G++
Sbjct: 1046 ANGASYSGYWKNNMKHGKGKFMFKNGRI 963

 Score = 40.8 bits (94), Expect = 0.005,   Method: Composition-based stats.
 Identities = 18/57 (31%), Positives = 32/57 (56%), Gaps = 4/57 (7%)
 Frame = -2

Query: 1043 YDGRWLSGKPHGRGVLKWPDGKMYSGMFRNGLEDGYGEYRIPN----KALNKEDHYV 1095
            YDG +++G  HG G   + +G  YSG ++N ++ G G++   N    + + + DH V
Sbjct: 1100 YDGEFVNGLRHGFGTFHYANGASYSGYWKNNMKHGKGKFMFKNGRIYEGMFEHDHIV 930

 Score = 40.4 bits (93), Expect = 0.006,   Method: Composition-based stats.
 Identities = 25/87 (28%), Positives = 45/87 (51%), Gaps = 5/87 (5%)
 Frame = -2

Query: 1115 EVFEGCFQDNMRHGHG---LLRSGKLTSSSP--SMFIGQWVMDKKAGYGVFDDITRGEKY 1169
            +++ G +++ ++HG G    L S    S  P  +M+ G++V   + G+G F     G  Y
Sbjct: 1205 QIYNGQWENGIQHGMGQHIWLLSRVPGSQYPMRNMYDGEFVNGLRHGFGTFH-YANGASY 1029

Query: 1170 MGMWQDDVCQGNGVVVTQFGLYYEGNF 1196
             G W++++  G G  + + G  YEG F
Sbjct: 1028 SGYWKNNMKHGKGKFMFKNGRIYEGMF 948
>26574
          Length = 441

 Score = 57.8 bits (138), Expect = 4e-08,   Method: Composition-based stats.
 Identities = 35/95 (36%), Positives = 47/95 (49%), Gaps = 1/95 (1%)
 Frame = +3

Query: 524 TWGKGKEGQLGHGDVLPRLQPLCVKCLDGKEVIHLEAGGSHSLALTAKSQVYSWGSNTFG 583
           TWGKG   +LGHG      +P  V  L GK+VI +  G  H +A T   +V++WG N  G
Sbjct: 3   TWGKGDYHRLGHGTDDHVRRPRRVSALQGKKVIDVACGSLHCVACTDSGEVFTWGDNDEG 182

Query: 584 QLGH-SEFPTTVPRLSKVSSENGVWSVAAGQDYSL 617
           QLG  +      PR+        +  VA G  +SL
Sbjct: 183 QLGDGTTNAIQRPRMVAALQGKKINRVACGSAHSL 287

 Score = 54.7 bits (130), Expect = 3e-07,   Method: Composition-based stats.
 Identities = 33/92 (35%), Positives = 45/92 (48%)
 Frame = +3

Query: 82  PLLESALVGHHVITVATGSFHSGAVTESGVVYMWGENAAGQCAVANQQYVPEPSPVSISD 141
           P   SAL G  VI VA GS H  A T+SG V+ WG+N  GQ        +  P  V+   
Sbjct: 63  PRRVSALQGKKVIDVACGSLHCVACTDSGEVFTWGDNDEGQLGDGTTNAIQRPRMVAALQ 242

Query: 142 SETSPSLAVRILQLACGEEHTLALSLSREIWA 173
            +       +I ++ACG  H+LA S  + + A
Sbjct: 243 GK-------KINRVACGSAHSLAWSTHKPVSA 317

 Score = 48.5 bits (114), Expect = 2e-05,   Method: Composition-based stats.
 Identities = 32/103 (31%), Positives = 51/103 (49%), Gaps = 2/103 (1%)
 Frame = +3

Query: 115 WGENAAGQCAVANQQYVPEPSPVSISDSETSPSLAVRILQLACGEEHTLALSLSREIWAW 174
           WG+    +       +V  P  VS    +       +++ +ACG  H +A + S E++ W
Sbjct: 6   WGKGDYHRLGHGTDDHVRRPRRVSALQGK-------KVIDVACGSLHCVACTDSGEVFTW 164

Query: 175 GTG--CQLGLITTTFPVTKPQKVEHLAGRVVLQVACGAFHSLA 215
           G     QLG  TT   + +P+ V  L G+ + +VACG+ HSLA
Sbjct: 165 GDNDEGQLGDGTTN-AIQRPRMVAALQGKKINRVACGSAHSLA 290

 Score = 43.5 bits (101), Expect = 6e-04,   Method: Composition-based stats.
 Identities = 22/54 (40%), Positives = 29/54 (53%)
 Frame = +3

Query: 521 EVWTWGKGKEGQLGHGDVLPRLQPLCVKCLDGKEVIHLEAGGSHSLALTAKSQV 574
           EV+TWG   EGQLG G      +P  V  L GK++  +  G +HSLA +    V
Sbjct: 150 EVFTWGDNDEGQLGDGTTNAIQRPRMVAALQGKKINRVACGSAHSLAWSTHKPV 311
>27967
          Length = 370

 Score = 55.1 bits (131), Expect = 2e-07,   Method: Composition-based stats.
 Identities = 30/86 (34%), Positives = 41/86 (47%)
 Frame = -1

Query: 1045 GRWLSGKPHGRGVLKWPDGKMYSGMFRNGLEDGYGEYRIPNKALNKEDHYVGHWKEGKMC 1104
            GR    + HG G    P+   Y GM+ NG   G G YR  N A      Y+G + + K  
Sbjct: 271  GRNERDERHGEGKATLPNKDTYEGMYENGKRHGQGIYRFKNGA-----RYIGEYMKNKKH 107

Query: 1105 GQGVYSYASGEVFEGCFQDNMRHGHG 1130
            GQG + Y  G  +EG + ++ R G G
Sbjct: 106  GQGTFIYPDGSKYEGGWVEDQRCGFG 29

 Score = 50.4 bits (119), Expect = 6e-06,   Method: Composition-based stats.
 Identities = 27/84 (32%), Positives = 42/84 (50%)
 Frame = -1

Query: 1077 GYGEYRIPNKALNKEDHYVGHWKEGKMCGQGVYSYASGEVFEGCFQDNMRHGHGLLRSGK 1136
            G G+  +PNK     D Y G ++ GK  GQG+Y + +G  + G +  N +HG      G 
Sbjct: 244  GEGKATLPNK-----DTYEGMYENGKRHGQGIYRFKNGARYIGEYMKNKKHGQ-----GT 95

Query: 1137 LTSSSPSMFIGQWVMDKKAGYGVF 1160
                  S + G WV D++ G+G +
Sbjct: 94   FIYPDGSKYEGGWVEDQRCGFGKY 23

 Score = 50.4 bits (119), Expect = 6e-06,   Method: Composition-based stats.
 Identities = 24/74 (32%), Positives = 40/74 (54%)
 Frame = -1

Query: 1042 TYDGRWLSGKPHGRGVLKWPDGKMYSGMFRNGLEDGYGEYRIPNKALNKEDHYVGHWKEG 1101
            TY+G + +GK HG+G+ ++ +G  Y G +    + G G +  P+ +      Y G W E 
Sbjct: 211  TYEGMYENGKRHGQGIYRFKNGARYIGEYMKNKKHGQGTFIYPDGS-----KYEGGWVED 47

Query: 1102 KMCGQGVYSYASGE 1115
            + CG G Y Y +G+
Sbjct: 46   QRCGFGKYYYVNGD 5

 Score = 36.6 bits (83), Expect = 0.083,   Method: Composition-based stats.
 Identities = 18/50 (36%), Positives = 26/50 (52%), Gaps = 1/50 (2%)
 Frame = -1

Query: 1037 RLKD-ATYDGRWLSGKPHGRGVLKWPDGKMYSGMFRNGLEDGYGEYRIPN 1085
            R K+ A Y G ++  K HG+G   +PDG  Y G +      G+G+Y   N
Sbjct: 160  RFKNGARYIGEYMKNKKHGQGTFIYPDGSKYEGGWVEDQRCGFGKYYYVN 11

 Score = 31.2 bits (69), Expect = 3.7,   Method: Composition-based stats.
 Identities = 24/92 (26%), Positives = 40/92 (43%)
 Frame = -1

Query: 1114 GEVFEGCFQDNMRHGHGLLRSGKLTSSSPSMFIGQWVMDKKAGYGVFDDITRGEKYMGMW 1173
            GE   G  + + RHG G     K T  +   + G +   K+ G G++     G +Y+G +
Sbjct: 286  GEYEGGRNERDERHGEG-----KATLPNKDTYEGMYENGKRHGQGIYR-FKNGARYIGEY 125

Query: 1174 QDDVCQGNGVVVTQFGLYYEGNFHLNKMMGNG 1205
              +   G G  +   G  YEG +  ++  G G
Sbjct: 124  MKNKKHGQGTFIYPDGSKYEGGWVEDQRCGFG 29
>07985
          Length = 1107

 Score = 43.1 bits (100), Expect = 8e-04,   Method: Composition-based stats.
 Identities = 26/69 (37%), Positives = 32/69 (46%)
 Frame = +1

Query: 1189 GLYYEGNFHLNKMMGNGVLLSEDDTIYEGEFSDDWTLSGKGTLTMPHGDYIEGYFSGEWG 1248
            G  Y+GN+   +M G G      +T YEGE  D     GKGTL  P+G   E      W 
Sbjct: 31   GSSYDGNYTNGRMEGKGQYCFPTETRYEGELRDG-MFHGKGTLFFPNGSKYE----ATWE 195

Query: 1249 SGIKITGTY 1257
             GI + G Y
Sbjct: 196  DGIALEGKY 222

 Score = 42.0 bits (97), Expect = 0.002,   Method: Composition-based stats.
 Identities = 22/74 (29%), Positives = 38/74 (51%)
 Frame = +1

Query: 1041 ATYDGRWLSGKPHGRGVLKWPDGKMYSGMFRNGLEDGYGEYRIPNKALNKEDHYVGHWKE 1100
            ++YDG + +G+  G+G   +P    Y G  R+G+  G G    PN +      Y   W++
Sbjct: 34   SSYDGNYTNGRMEGKGQYCFPTETRYEGELRDGMFHGKGTLFFPNGS-----KYEATWED 198

Query: 1101 GKMCGQGVYSYASG 1114
            G +  +G Y++A G
Sbjct: 199  G-IALEGKYTFADG 237

 Score = 37.0 bits (84), Expect = 0.063,   Method: Composition-based stats.
 Identities = 22/76 (28%), Positives = 34/76 (44%)
 Frame = +1

Query: 1063 GKMYSGMFRNGLEDGYGEYRIPNKALNKEDHYVGHWKEGKMCGQGVYSYASGEVFEGCFQ 1122
            G  Y G + NG  +G G+Y  P      E  Y G  ++G   G+G   + +G  +E  ++
Sbjct: 31   GSSYDGNYTNGRMEGKGQYCFPT-----ETRYEGELRDGMFHGKGTLFFPNGSKYEATWE 195

Query: 1123 DNMRHGHGLLRSGKLT 1138
            D      G+   GK T
Sbjct: 196  D------GIALEGKYT 225

 Score = 32.0 bits (71), Expect = 2.0,   Method: Composition-based stats.
 Identities = 15/47 (31%), Positives = 24/47 (51%)
 Frame = +1

Query: 1028 AKYTFYKDTRLKDATYDGRWLSGKPHGRGVLKWPDGKMYSGMFRNGL 1074
             +Y F  +TR     Y+G    G  HG+G L +P+G  Y   + +G+
Sbjct: 79   GQYCFPTETR-----YEGELRDGMFHGKGTLFFPNGSKYEATWEDGI 204
>03352
          Length = 935

 Score = 38.1 bits (87), Expect = 0.027,   Method: Compositional matrix adjust.
 Identities = 28/96 (29%), Positives = 44/96 (45%)
 Frame = +2

Query: 29  SLTPERLPGWGGKTVLQAALGVRHGVLLTEDGEVYSFGTLPWKSESAEICPSSPLLESAL 88
           S+ P+++     K V+  A       ++T+DGEVY FG      +    C  +    + L
Sbjct: 176 SVKPKKMIRVENKQVVFVACNSGSSAVVTKDGEVYMFG------KDTSHCDHASGHVTDL 337

Query: 89  VGHHVITVATGSFHSGAVTESGVVYMWGENAAGQCA 124
               V  VA G  H+ A+T  G ++ +G N  GQC 
Sbjct: 338 KDVVVTQVALGKAHTVALTSKGQLFTFGINNKGQCG 445
>12101
          Length = 1020

 Score = 38.1 bits (87), Expect = 0.034,   Method: Compositional matrix adjust.
 Identities = 35/132 (26%), Positives = 59/132 (44%), Gaps = 4/132 (3%)
 Frame = -2

Query: 496 VKTRTVVLTPTYSGEADALLPSLRTEVWTWGKGKEGQLGHGDVLPRL-QPLCVKCLDGKE 554
           VKT    +     G+   L+          G+ + G+LG G V   + +P  +  L+GK 
Sbjct: 788 VKTEIKDVKQIAGGQHHTLILDNNMRCLAVGRPEYGRLGLGKVTEVVTKPTAITQLNGK- 612

Query: 555 VIHLEAGGSHSLALTAKSQVYSWGSNTFGQLGHSEFPTTVPRL---SKVSSENGVWSVAA 611
           V ++  G + S  +T   ++YSWG  +  QLG  +    V  +   SK +    V     
Sbjct: 611 VNYVACGEACSFXITNDGKLYSWGMGSLLQLGVGDGDDEVVPVEVSSKNTQNKKVLLADG 432

Query: 612 GQDYSLFLVDTE 623
           G  +S+FLV+ +
Sbjct: 431 GGQHSVFLVEAD 396

 Score = 33.9 bits (76), Expect = 0.57,   Method: Compositional matrix adjust.
 Identities = 25/67 (37%), Positives = 33/67 (49%), Gaps = 2/67 (2%)
 Frame = -2

Query: 152 ILQLACGEEHTLALSLSREIWAWGTG--CQLGLITTTFPVTKPQKVEHLAGRVVLQVACG 209
           + Q+A G+ HTL L  +    A G     +LGL   T  VTKP  +  L G+V   VACG
Sbjct: 767 VKQIAGGQHHTLILDNNMRCLAVGRPEYGRLGLGKVTEVVTKPTAITQLNGKVNY-VACG 591

Query: 210 AFHSLAL 216
              S  +
Sbjct: 590 EACSFXI 570
>20162
          Length = 1121

 Score = 37.0 bits (84), Expect = 0.069,   Method: Compositional matrix adjust.
 Identities = 17/47 (36%), Positives = 30/47 (63%), Gaps = 1/47 (2%)
 Frame = +1

Query: 554 EVIHLEAGGSHSLALTAKSQVYSWGSNTFGQLGHSE-FPTTVPRLSK 599
           ++  +  G +H+L + +K +++SWG   +G+LGH+E     VPRL K
Sbjct: 310 DIREVACGLNHTLIMDSKKRLFSWGFGGYGRLGHAEPKDELVPRLIK 450

 Score = 36.2 bits (82), Expect = 0.13,   Method: Compositional matrix adjust.
 Identities = 25/89 (28%), Positives = 41/89 (46%), Gaps = 9/89 (10%)
 Frame = +1

Query: 98  TGSFHSGAVTESGVVYMWGENAAGQCAVANQ--QYVPEPSPVSIS-------DSETSPSL 148
            G+ +S    E G +   G N+ G+  V +   +Y  E +P  +S       D    P  
Sbjct: 133 NGNLYSFGCPEYGQL---GHNSDGKYFVTSNKMEYKCEMTPRKVSVFIEKTRDGHVMPIT 303

Query: 149 AVRILQLACGEEHTLALSLSREIWAWGTG 177
            V I ++ACG  HTL +   + +++WG G
Sbjct: 304 DVDIREVACGLNHTLIMDSKKRLFSWGFG 390

 Score = 35.4 bits (80), Expect = 0.21,   Method: Compositional matrix adjust.
 Identities = 19/72 (26%), Positives = 33/72 (45%), Gaps = 2/72 (2%)
 Frame = +1

Query: 509 GEADALLPSLRTEVWTWGKGKEGQLGHGDVLPRLQPLCVKCLD--GKEVIHLEAGGSHSL 566
           G    L+   +  +++WG G  G+LGH +    L P  +K  D  G+    ++ G S  +
Sbjct: 331 GLNHTLIMDSKKRLFSWGFGGYGRLGHAEPKDELVPRLIKFFDGPGRGGSQIQCGSSFCM 510

Query: 567 ALTAKSQVYSWG 578
            +     +Y WG
Sbjct: 511 TVNEHGALYFWG 546

 Score = 30.4 bits (67), Expect = 5.5,   Method: Compositional matrix adjust.
 Identities = 40/186 (21%), Positives = 69/186 (37%), Gaps = 9/186 (4%)
 Frame = +1

Query: 43  VLQAALGVRHGVLLTEDGEVYS-----FGTLPWKSESAEICPSSPLLESALVGHHVITVA 97
           + + A G+ H +++     ++S     +G L       E+ P          G     + 
Sbjct: 313 IREVACGLNHTLIMDSKKRLFSWGFGGYGRLGHAEPKDELVPRLIKFFDG-PGRGGSQIQ 489

Query: 98  TGSFHSGAVTESGVVYMWGENAAGQCAVANQQYVPEPSPVSISDSETSPSLAVRILQLAC 157
            GS     V E G +Y WG++     A    + V + S               ++  + C
Sbjct: 490 CGSSFCMTVNEHGALYFWGQSKPTGEATMYPKLVQDLS-------------GWKVRSIGC 630

Query: 158 GEEHTLALSLSREIWAWG---TGCQLGLITTTFPV-TKPQKVEHLAGRVVLQVACGAFHS 213
               ++ L     + +WG   T  +LG         T  Q+V+ L G  V  VACG  H+
Sbjct: 631 CYR-SIVLCADDSVVSWGPSPTYGELGYGENKMKSSTVAQEVKPLDGVYVHDVACGYAHT 807

Query: 214 LALVQC 219
           L + +C
Sbjct: 808 LMIARC 825
>32825
          Length = 379

 Score = 34.7 bits (78), Expect = 0.34,   Method: Composition-based stats.
 Identities = 19/52 (36%), Positives = 27/52 (51%)
 Frame = +1

Query: 1063 GKMYSGMFRNGLEDGYGEYRIPNKALNKEDHYVGHWKEGKMCGQGVYSYASG 1114
            G  Y GM+  G  DG+GE       ++    YVG +KE +M G+G Y +  G
Sbjct: 22   GTKYVGMWNTGKWDGHGEL------IHANHKYVGTFKENRMEGKGKYVFDIG 159
>39525
          Length = 450

 Score = 34.3 bits (77), Expect = 0.47,   Method: Composition-based stats.
 Identities = 18/48 (37%), Positives = 29/48 (60%), Gaps = 2/48 (4%)
 Frame = -3

Query: 544 PLCVKCLDGKEVIHLEAG--GSHSLALTAKSQVYSWGSNTFGQLGHSE 589
           P  +  L+G +V  + +G    H +A+T + +VY+WG N  GQLG S+
Sbjct: 193 PHRMAALEGIKVRTIASGCNACHCVAITDEGKVYTWGRNEKGQLGLSD 50
>07231
          Length = 2836

 Score = 32.0 bits (71), Expect = 2.4,   Method: Composition-based stats.
 Identities = 12/41 (29%), Positives = 23/41 (56%)
 Frame = -3

Query: 574  VYSWGSNTFGQLGHSEFPTTVPRLSKVSSENGVWSVAAGQD 614
            +Y W      Q+  +  PTT+P++ K+++ N  W +  G+D
Sbjct: 1454 MYMW------QIFMTSHPTTIPQIKKINNANNWWXILVGED 1350
>17531
          Length = 1000

 Score = 31.2 bits (69), Expect = 3.5,   Method: Composition-based stats.
 Identities = 16/47 (34%), Positives = 24/47 (51%)
 Frame = -3

Query: 1518 GVQKKFWPATLSILGESKKVLSTTKDACFASAVECLQQISTTFTPSD 1564
            GV  K W A++  LGE+ KV   T  +C    + C+   ++   PSD
Sbjct: 155  GVNTKDWKASIL*LGETHKVCVATCVSCVVH-INCVSSTTSEIIPSD 18
>33425
          Length = 477

 Score = 30.8 bits (68), Expect = 4.6,   Method: Compositional matrix adjust.
 Identities = 26/80 (32%), Positives = 36/80 (45%), Gaps = 4/80 (5%)
 Frame = -3

Query: 112 VYMWGENAAGQCAVANQQYVPEPSPVSISDSETSPSL-AVRILQLACGEEHTL---ALSL 167
           VY WG NA GQC    Q  +PEP    +  +     L  V + Q+A G  H++   A+  
Sbjct: 463 VYAWGNNAMGQCG---QGSLPEP---HLPPTARWWGLEGVPVQQIAAGTSHSVVWTAMPS 302

Query: 168 SREIWAWGTGCQLGLITTTF 187
            R + AW     + L   TF
Sbjct: 301 DRHVIAWHRPFCVDLQEATF 242
>20193
          Length = 948

 Score = 29.6 bits (65), Expect = 9.8,   Method: Compositional matrix adjust.
 Identities = 18/61 (29%), Positives = 30/61 (49%)
 Frame = -2

Query: 1292 EECWRQLGCESPGQGEVWKAWDNIAVALTTNRRQHRDSPEILSRSQTQTLESLEYIPQHI 1351
              CW     +SPG+      W+ +AV     RR+HR  P   +R++T T  +L ++ +  
Sbjct: 224  HRCWLHRSNQSPGRSRSQDVWE-MAV-WGDGRREHRXHPST-ARTETLTCRTLNHLAREC 54

Query: 1352 G 1352
            G
Sbjct: 53   G 51
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|118601017|ref|NP_031861.2| dynactin 1 [Mus musculus]
         (1281 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

10547                                                                  70   7e-12
20604                                                                  63   1e-09
20779                                                                  60   6e-09
18826                                                                  60   7e-09
26691                                                                  54   5e-07
06995                                                                  40   0.006
16375                                                                  30   7.6  
09202                                                                  30   9.1  
>10547
          Length = 856

 Score = 69.7 bits (169), Expect = 7e-12,   Method: Composition-based stats.
 Identities = 30/56 (53%), Positives = 38/56 (67%)
 Frame = +2

Query: 41 RGTVAYVGATLFATGKWVGVILDEAKGKNDGTVQGRKYFTCDEGHGIFVRQSQIQV 96
          RGTV YVG T F  G WVG+  DE  GKNDG+V G++YF C   +G FV+ S ++V
Sbjct: 5  RGTVRYVGETDFKPGMWVGIQYDEPHGKNDGSVAGKRYFECQPKYGGFVKPSNVEV 172
>20604
          Length = 678

 Score = 62.8 bits (151), Expect = 1e-09,   Method: Composition-based stats.
 Identities = 27/53 (50%), Positives = 35/53 (66%)
 Frame = +3

Query: 42  GTVAYVGATLFATGKWVGVILDEAKGKNDGTVQGRKYFTCDEGHGIFVRQSQI 94
           G  A  G   FA G W+GV LD+ +GKNDG+V+G +YF C   HGIFVR  ++
Sbjct: 96  GHGALCGTCAFAVGNWIGVELDQPEGKNDGSVKGIRYFNCRGRHGIFVRPDKL 254
>20779
          Length = 490

 Score = 60.1 bits (144), Expect = 6e-09,   Method: Composition-based stats.
 Identities = 32/75 (42%), Positives = 41/75 (54%)
 Frame = +3

Query: 46  YVGATLFATGKWVGVILDEAKGKNDGTVQGRKYFTCDEGHGIFVRQSQIQVFEDGADTTS 105
           Y+G T FA G W GV LDE  GKNDGTV G +YF C    G+FV  +++ +        S
Sbjct: 3   YLGETQFAPGNWCGVELDEGSGKNDGTVDGIRYFECKPRFGVFVPIAKVSL--------S 158

Query: 106 PETPDSSASKVLKRE 120
           P T  +  S+   RE
Sbjct: 159 PSTKKTRLSRTGSRE 203
>18826
          Length = 490

 Score = 59.7 bits (143), Expect = 7e-09,   Method: Composition-based stats.
 Identities = 34/96 (35%), Positives = 48/96 (50%)
 Frame = +3

Query: 2   AQSRRHMSSRTPSGSRMSTEASARPLRVGSRVEVIGKGHRGTVAYVGATLFATGKWVGVI 61
           A  RR  S    +    +TE       +G RV V G    G +AY+G T FA G W G++
Sbjct: 189 ATGRRRSSDHNSTVLTANTEQ----FIIGQRVWV-GGLRSGQIAYIGETHFAPGDWAGIV 353

Query: 62  LDEAKGKNDGTVQGRKYFTCDEGHGIFVRQSQIQVF 97
           LDE  GK      G++YF C+   GIF R +++  +
Sbjct: 354 LDEPNGKKRWMRFGQRYFQCEPKRGIFSRLTRLTTY 461
>26691
          Length = 395

 Score = 53.5 bits (127), Expect = 5e-07,   Method: Composition-based stats.
 Identities = 29/65 (44%), Positives = 37/65 (56%)
 Frame = +2

Query: 24  ARPLRVGSRVEVIGKGHRGTVAYVGATLFATGKWVGVILDEAKGKNDGTVQGRKYFTCDE 83
           A  L VG R+ + G    G + +VG T  A G W G+ L +A G +DG V GR+YFTC  
Sbjct: 119 AEKLTVGKRILISGV-KPGVLRFVGQTSLAPGYWCGIELFDASGLHDGEVDGRRYFTCKP 295

Query: 84  GHGIF 88
             GIF
Sbjct: 296 FRGIF 310
>06995
          Length = 1566

 Score = 40.0 bits (92), Expect = 0.006,   Method: Composition-based stats.
 Identities = 16/63 (25%), Positives = 34/63 (53%)
 Frame = -1

Query: 1219 GATVPTDFATFPSSAFLRAKEEQQDDTVYMGKVTFSCAAGLGQRHRLVLTQEQLHQLHSR 1278
            G +    F++FP+  F +   E+   ++ +G++   C  G G+   + +  +QLH +H+R
Sbjct: 1566 GTSAHETFSSFPTPQFAKVLYEKCGQSLKVGRIRMPCTGGKGETIPVNIQPDQLHTIHAR 1387

Query: 1279 LIS 1281
             +S
Sbjct: 1386 FLS 1378
>16375
          Length = 1791

 Score = 29.6 bits (65), Expect = 7.6,   Method: Compositional matrix adjust.
 Identities = 18/53 (33%), Positives = 31/53 (58%)
 Frame = +3

Query: 480 ETELELREQLDMAGARVREAQKRVEAAQETVADYQQTIKKYRQLTAHLQDVNR 532
           E + E  + L +A + V   Q+R++  +ETV  YQ+ +K+ RQ    + D+NR
Sbjct: 585 EPDYETHQGLKIAQSTVHSLQQRIQQKEETVVKYQELLKQARQ---DMLDMNR 734
>09202
          Length = 757

 Score = 29.6 bits (65), Expect = 9.1,   Method: Composition-based stats.
 Identities = 22/70 (31%), Positives = 35/70 (50%), Gaps = 2/70 (2%)
 Frame = +1

Query: 700 DFLIELLHKDQLDETVNVEPLTKAIKYYQHLYSIHLAEQPEDSTMQ-LADHIKFTQSALD 758
           DF + +L K     T+ +      +KYY HLYS+++A      T   L+ ++K  QS   
Sbjct: 259 DFFVRILSK-----TLRITCQQFPLKYYIHLYSVYIAYHAGKLTKSPLS*NLKLFQSMKM 423

Query: 759 C-MGVEVGRL 767
           C + VEV  +
Sbjct: 424 CALSVEVSSI 453
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6755995|ref|NP_035845.1| WD repeat domain 1 [Mus
musculus]
         (606 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

12574                                                                  69   7e-12
19949                                                                  59   6e-09
01249                                                                  57   2e-08
13335                                                                  56   3e-08
30256                                                                  54   3e-07
00561                                                                  51   2e-06
03387                                                                  50   2e-06
03395                                                                  48   1e-05
02147                                                                  48   1e-05
19498                                                                  48   1e-05
02960                                                                  47   2e-05
15337                                                                  47   3e-05
01768                                                                  45   6e-05
31384                                                                  45   8e-05
12806                                                                  45   8e-05
31474                                                                  45   9e-05
17598                                                                  44   1e-04
33180                                                                  43   5e-04
26107                                                                  42   7e-04
38177                                                                  42   0.001
01598                                                                  40   0.003
29912                                                                  40   0.003
27465                                                                  39   0.006
25930                                                                  39   0.006
13278                                                                  39   0.009
19863                                                                  38   0.011
01805                                                                  38   0.015
17266                                                                  37   0.022
27806                                                                  37   0.025
15780                                                                  37   0.027
27525                                                                  37   0.031
30295                                                                  37   0.033
01327                                                                  36   0.040
14555                                                                  35   0.059
01462                                                                  35   0.069
07665                                                                  35   0.076
20662                                                                  35   0.079
21105                                                                  35   0.12 
16199                                                                  34   0.13 
02090                                                                  34   0.16 
34005                                                                  34   0.18 
27681                                                                  34   0.18 
00825                                                                  34   0.19 
25526                                                                  34   0.20 
03044                                                                  33   0.24 
11493                                                                  33   0.25 
12960                                                                  33   0.28 
14500                                                                  33   0.30 
25400                                                                  33   0.32 
03156                                                                  33   0.33 
16105                                                                  33   0.37 
19140                                                                  32   0.56 
10264                                                                  32   0.57 
36111                                                                  32   0.57 
35844                                                                  32   0.99 
04524                                                                  32   1.1  
31118                                                                  31   1.1  
10162                                                                  31   1.3  
12409                                                                  31   1.3  
11915                                                                  31   1.3  
13486                                                                  31   1.5  
04358                                                                  31   1.5  
17602                                                                  31   1.8  
17298                                                                  30   1.9  
15118                                                                  30   1.9  
13890                                                                  30   2.2  
27475                                                                  30   2.4  
21921                                                                  30   2.8  
07542                                                                  30   3.1  
18981                                                                  30   3.1  
38362                                                                  30   3.1  
31864                                                                  30   3.7  
21960                                                                  29   4.5  
37142                                                                  29   4.6  
14105                                                                  29   6.6  
27270                                                                  29   7.1  
25880                                                                  28   8.3  
>12574
          Length = 521

 Score = 68.6 bits (166), Expect = 7e-12,   Method: Compositional matrix adjust.
 Identities = 42/106 (39%), Positives = 60/106 (56%), Gaps = 3/106 (2%)
 Frame = +3

Query: 175 EGPPFKFKFTIGDHSRFVNCVRFSPDGNRFATASADGQIFI---YDGKTGEKVCALGESK 231
           + P +  KFT+  H++ ++ V+FSP+G+  A++SAD  I I   YDGK  EK  A     
Sbjct: 144 QKPTYTLKFTLAGHTKALSAVKFSPNGDWLASSSADKLIKIWGAYDGKF-EKTIA----- 305

Query: 232 AHDGGIYAISWSPDSTHLLSASGDKTSKIWDVNVNSVVSTFPMGSN 277
            H  G+  ++WS DS  L SAS DKT KIW+ +    + T    SN
Sbjct: 306 GHKLGLSDVAWSSDSKLLCSASDDKTLKIWEFSTGKCMKTLKGHSN 443

 Score = 36.6 bits (83), Expect = 0.029,   Method: Compositional matrix adjust.
 Identities = 20/71 (28%), Positives = 36/71 (50%)
 Frame = +3

Query: 492 VTDVAYSHDGAFLAVCDASKVVTVFSVADGYSENNVFYGHHAKIVCLAWSPDNEHFASGG 551
           ++ V +S +G +LA   A K++ ++   DG  E  +  GH   +  +AWS D++   S  
Sbjct: 195 LSAVKFSPNGDWLASSSADKLIKIWGAYDGKFEKTI-AGHKLGLSDVAWSSDSKLLCSAS 371

Query: 552 MDMMVYVWTLS 562
            D  + +W  S
Sbjct: 372 DDKTLKIWEFS 404

 Score = 33.5 bits (75), Expect = 0.24,   Method: Compositional matrix adjust.
 Identities = 23/96 (23%), Positives = 46/96 (47%), Gaps = 3/96 (3%)
 Frame = +3

Query: 57  HAHQVVVAKYAPSGFYIASGDISGKLRIWDTTQKEHLLKYEYQPFAGK---IKDIAWTED 113
           H   +   K++P+G ++AS      ++IW         K+E +  AG    + D+AW+ D
Sbjct: 183 HTKALSAVKFSPNGDWLASSSADKLIKIWGAYDG----KFE-KTIAGHKLGLSDVAWSSD 347

Query: 114 SKRIAVVGEGREKFGAVFLWDTGSSVGEITGHNKVI 149
           SK +    +  +K   ++ + TG  +  + GH+  +
Sbjct: 348 SKLLCSASD--DKTLKIWEFSTGKCMKTLKGHSNYV 449
>19949
          Length = 903

 Score = 58.9 bits (141), Expect = 6e-09,   Method: Compositional matrix adjust.
 Identities = 33/97 (34%), Positives = 50/97 (51%)
 Frame = +2

Query: 183 FTIGDHSRFVNCVRFSPDGNRFATASADGQIFIYDGKTGEKVCALGESKAHDGGIYAISW 242
           +T   H+  V C+RFSPDG   A+AS DG + ++D   G+    L + K H   +  I +
Sbjct: 101 YTYKGHTGCVCCLRFSPDGRWIASASEDGLVKLWDLTAGK---LLTDLKLHRDAVNTIEF 271

Query: 243 SPDSTHLLSASGDKTSKIWDVNVNSVVSTFPMGSNVL 279
            P    L S S D+T K WD+    ++ST    +N +
Sbjct: 272 HPHEFLLASGSADRTVKFWDLETFQLISTTEPEANSI 382

 Score = 54.3 bits (129), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 38/147 (25%), Positives = 67/147 (45%), Gaps = 2/147 (1%)
 Frame = +2

Query: 66  YAPSGFYIASGDISGKLRIWDTTQKEHLLKYEYQPFAGKIKDIAWTEDSKRIAVVGEGRE 125
           + P G Y ASG +   +++WD  +K  +  Y Y+   G +  + ++ D + IA   E   
Sbjct: 17  FHPYGAYTASGSMDCNVKLWDIRRKGCI--YTYKGHTGCVCCLRFSPDGRWIASASED-- 184

Query: 126 KFGAVFLWD--TGSSVGEITGHNKVINSVDIKQTRPYRLATGSDDNCAAFFEGPPFKFKF 183
             G V LWD   G  + ++  H   +N+++      + LA+GS D    F++   F+   
Sbjct: 185 --GLVKLWDLTAGKLLTDLKLHRDAVNTIEF-HPHEFLLASGSADRTVKFWDLETFQLIS 355

Query: 184 TIGDHSRFVNCVRFSPDGNRFATASAD 210
           T    +  +  + F PDG    + S D
Sbjct: 356 TTEPEANSIRSILFHPDGVCLYSGSKD 436

 Score = 33.1 bits (74), Expect = 0.33,   Method: Compositional matrix adjust.
 Identities = 25/81 (30%), Positives = 39/81 (48%), Gaps = 3/81 (3%)
 Frame = +2

Query: 527 VFYGHHAKIVCLAWSPDNEHFASGGMDMMVYVWTLSDPETKVKIQDAHRLHH--VSSLAW 584
            + GH   + CL +SPD    AS   D +V +W L    T  K+    +LH   V+++ +
Sbjct: 104 TYKGHTGCVCCLRFSPDGRWIASASEDGLVKLWDL----TAGKLLTDLKLHRDAVNTIEF 271

Query: 585 -LDEHTLVTTSHDASVKEWTI 604
              E  L + S D +VK W +
Sbjct: 272 HPHEFLLASGSADRTVKFWDL 334

 Score = 31.6 bits (70), Expect = 0.90,   Method: Compositional matrix adjust.
 Identities = 34/162 (20%), Positives = 59/162 (36%)
 Frame = +2

Query: 192 VNCVRFSPDGNRFATASADGQIFIYDGKTGEKVCALGESKAHDGGIYAISWSPDSTHLLS 251
           V  + F P G   A+ S D  + ++D +   K C +   K H G +  + +SPD   + S
Sbjct: 2   VKSLDFHPYGAYTASGSMDCNVKLWDIR--RKGC-IYTYKGHTGCVCCLRFSPDGRWIAS 172

Query: 252 ASGDKTSKIWDVNVNSVVSTFPMGSNVLDQQLGCLWQKDHLLSISLSGYINYLDKNNPSK 311
           AS D   K+WD+    +++                                         
Sbjct: 173 ASEDGLVKLWDLTAGKLLTD---------------------------------------- 232

Query: 312 PLRVIKGHSKSIQCLTVHRNGGKSYIYSGSHDGHINYWDSET 353
               +K H  ++  +  H +  +  + SGS D  + +WD ET
Sbjct: 233 ----LKLHRDAVNTIEFHPH--EFLLASGSADRTVKFWDLET 340
>01249
          Length = 1743

 Score = 57.0 bits (136), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 51/196 (26%), Positives = 93/196 (47%), Gaps = 22/196 (11%)
 Frame = -1

Query: 195  VRFSPDGNRFATASADGQIFIYD-----GKTGEKVCALGESK---AHDGGIYA--ISWSP 244
            ++F+ DG++F  A++ G + I+D       T ++   L   +   AH   I    +    
Sbjct: 1353 IQFTDDGSQFVVATSSGHLNIWDFARVVTTTSQRARGLKPGRTINAHSEPITGLHVGCGG 1174

Query: 245  DSTHLLSASGDKTSKIWDVNVNSVVSTF----PMGSNVLDQQ----LGCLWQKDHLLSIS 296
             +  + S+S D T K+WD+   +++ T      +G  ++D+Q    L  L   D L S  
Sbjct: 1173 PAARVASSSSDGTCKLWDMLSGALLRTMVYETGVGCLIMDKQEHFLLAGLDNGDILCS-P 997

Query: 297  LSGYIN----YLDKNNPSKPLRVIKGHSKSIQCLTVHRNGGKSYIYSGSHDGHINYWDSE 352
            L G I+    ++ K+      RV++GHS ++ CL    +G +  + SGS +G +  W+ E
Sbjct: 996  LFGQISQSEVFVSKHTTKAGERVLQGHSDAVTCLAFSSDGQR--LASGSQNGKVIIWNME 823

Query: 353  TGENDSFSGKGHTNQV 368
            +G++ S    G    V
Sbjct: 822  SGDSTSLDISGAVGNV 775

 Score = 33.9 bits (76), Expect = 0.18,   Method: Compositional matrix adjust.
 Identities = 13/37 (35%), Positives = 19/37 (51%)
 Frame = -1

Query: 525 NNVFYGHHAKIVCLAWSPDNEHFASGGMDMMVYVWTL 561
             V  GH   + CLA+S D +  ASG  +  V +W +
Sbjct: 936 ERVLQGHSDAVTCLAFSSDGQRLASGSQNGKVIIWNM 826
>13335
          Length = 863

 Score = 56.2 bits (134), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 52/221 (23%), Positives = 87/221 (39%), Gaps = 25/221 (11%)
 Frame = +1

Query: 21  KILGGDPKGDHFLY-TNGKCVILRNIDNPAIADIYTEHAHQVVVAKYAPSGFYIASGDIS 79
           ++    P   H +  ++   + +  +    +   Y  H   V+   Y+P+G Y+ SG  +
Sbjct: 73  RVCKFSPSSSHLVSGSDDDTICMWEVATQKLVRSYVGHEDSVMALAYSPNGHYLVSGSPN 252

Query: 80  GKLRIWDTT--QKEHLLKY-----------EYQPFAGKIKDIAWTEDSKRIAVVGEGREK 126
           G L +WD +     HL              E+ P  G     A  E+S    ++     K
Sbjct: 253 GDLYVWDASFGHCRHLTLRVDAHDLGVTCCEFSPTFGT----ACAENSSTCNLLLATGGK 420

Query: 127 FGAVFLWDTGSSVGE----------ITGHNKVINSVDIKQTRPYRLATGSDDNCAAFFEG 176
              + LW   + VG           ++GH+ ++ +     +    LA+GS D     ++ 
Sbjct: 421 DNLIKLWTFSAQVGSPEVTLQCRDILSGHSDLVMACAFSPSSAL-LASGSFDKSVRLWDS 597

Query: 177 PPFKFKFTI-GDHSRFVNCVRFSPDGNRFATASADGQIFIY 216
                 F+I   HSRFV C  FS DG   A+ S D  I I+
Sbjct: 598 VKGVALFSIEACHSRFVTCCAFSIDGTLLASGSMDRIIKIW 720

 Score = 45.8 bits (107), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 59/246 (23%), Positives = 102/246 (41%), Gaps = 26/246 (10%)
 Frame = +1

Query: 130 VFLWD--TGSSVGEITGHNKVINSVDIKQTRPY--RLATGSDDNCAAFFEGPPFKFKFTI 185
           V +WD  TGS  GE    +K  +S+ + +  P    L +GSDD+    +E    K   + 
Sbjct: 4   VIVWDVKTGSIKGEYQHASK--SSIRVCKFSPSSSHLVSGSDDDTICMWEVATQKLVRSY 177

Query: 186 GDHSRFVNCVRFSPDGNRFATASADGQIFIYDGKTGEKVCALGESKAHDGGIYAISWSP- 244
             H   V  + +SP+G+   + S +G ++++D   G          AHD G+    +SP 
Sbjct: 178 VGHEDSVMALAYSPNGHYLVSGSPNGDLYVWDASFGHCRHLTLRVDAHDLGVTCCEFSPT 357

Query: 245 ---------DSTHLLSASGDKTSKIWDVNVNSVVSTFPMGSNVLDQQLGCLWQKDHLLSI 295
                     + +LL A+G K + I     ++ V +  +     D   G     D +++ 
Sbjct: 358 FGTACAENSSTCNLLLATGGKDNLIKLWTFSAQVGSPEVTLQCRDILSG---HSDLVMAC 528

Query: 296 SLSGYINYLDKNNPSKPLRV---IKG---------HSKSIQCLTVHRNGGKSYIYSGSHD 343
           + S     L   +  K +R+   +KG         HS+ + C     +G  + + SGS D
Sbjct: 529 AFSPSSALLASGSFDKSVRLWDSVKGVALFSIEACHSRFVTCCAFSIDG--TLLASGSMD 702

Query: 344 GHINYW 349
             I  W
Sbjct: 703 RIIKIW 720

 Score = 38.1 bits (87), Expect = 0.010,   Method: Compositional matrix adjust.
 Identities = 22/75 (29%), Positives = 35/75 (46%)
 Frame = +1

Query: 492 VTDVAYSHDGAFLAVCDASKVVTVFSVADGYSENNVFYGHHAKIVCLAWSPDNEHFASGG 551
           V   A+S   A LA     K V ++    G +  ++   H   + C A+S D    ASG 
Sbjct: 517 VMACAFSPSSALLASGSFDKSVRLWDSVKGVALFSIEACHSRFVTCCAFSIDGTLLASGS 696

Query: 552 MDMMVYVWTLSDPET 566
           MD ++ +W L+D  +
Sbjct: 697 MDRIIKIWKLTDTSS 741

 Score = 31.6 bits (70), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 20/81 (24%), Positives = 32/81 (39%)
 Frame = +1

Query: 525 NNVFYGHHAKIVCLAWSPDNEHFASGGMDMMVYVWTLSDPETKVKIQDAHRLHHVSSLAW 584
            ++  GH   ++  A+SP +   ASG  D  V +W          I+  H          
Sbjct: 487 RDILSGHSDLVMACAFSPSSALLASGSFDKSVRLWDSVKGVALFSIEACHSRFVTCCAFS 666

Query: 585 LDEHTLVTTSHDASVKEWTIT 605
           +D   L + S D  +K W +T
Sbjct: 667 IDGTLLASGSMDRIIKIWKLT 729

 Score = 29.3 bits (64), Expect = 4.5,   Method: Compositional matrix adjust.
 Identities = 32/132 (24%), Positives = 55/132 (41%), Gaps = 21/132 (15%)
 Frame = +1

Query: 492 VTDVAYSHDGAFLAVCDASKVVTVFSVADGYSENNVFY--GHHAKIVCLAWSPD------ 543
           V  +AYS +G +L     +  + V+  + G+  +       H   + C  +SP       
Sbjct: 196 VMALAYSPNGHYLVSGSPNGDLYVWDASFGHCRHLTLRVDAHDLGVTCCEFSPTFGTACA 375

Query: 544 ------NEHFASGGMDMMVYVWTLS----DPETKVKIQDAHRLHH--VSSLAWLDEHTLV 591
                 N   A+GG D ++ +WT S     PE  ++ +D    H   V + A+     L+
Sbjct: 376 ENSSTCNLLLATGGKDNLIKLWTFSAQVGSPEVTLQCRDILSGHSDLVMACAFSPSSALL 555

Query: 592 TT-SHDASVKEW 602
            + S D SV+ W
Sbjct: 556 ASGSFDKSVRLW 591

 Score = 28.5 bits (62), Expect = 8.1,   Method: Compositional matrix adjust.
 Identities = 12/35 (34%), Positives = 20/35 (57%)
 Frame = +1

Query: 528 FYGHHAKIVCLAWSPDNEHFASGGMDMMVYVWTLS 562
           + GH   ++ LA+SP+  +  SG  +  +YVW  S
Sbjct: 175 YVGHEDSVMALAYSPNGHYLVSGSPNGDLYVWDAS 279
>30256
          Length = 961

 Score = 53.5 bits (127), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 65/300 (21%), Positives = 123/300 (41%), Gaps = 10/300 (3%)
 Frame = +3

Query: 109 AWTEDSKRIAVVGEGREKFGAVFLWDTGSSVGEITGHNKVINSVDIKQTRPYRLATGSDD 168
            W+       V+    ++   V+  DTG     + GH+  +  + +      ++ +GS D
Sbjct: 51  VWSSQMTGNTVISGSTDRSLKVWNADTGVCTHTLYGHSSTVRCLSLS---GKKVVSGSRD 221

Query: 169 NCAAFFEGPPFKFKFTIGDHSRFVNCVRFSPDGNRFATASADGQIFIYDGKTGEKVCALG 228
                ++         +  H   V CV++  DG R  + + D  + ++D  T      L 
Sbjct: 222 ATLRVWDIESGHCLNVLLGHMAAVRCVQY--DGKRVVSGAXDYTVRVWDPDTAS---CLH 386

Query: 229 ESKAHDGGIYAISWSPDSTHLLSASGDKTSKIWDVNVNSVVSTFPMGSNVLDQQLGCLWQ 288
             + H   +Y++ +  D  +++S S D + ++WDV    +V T  MG   L   L     
Sbjct: 387 TLQGHTNRVYSLQF--DGVYVVSGSLDTSIRVWDVRCGKLVHTL-MGHQSLTSGLE---L 548

Query: 289 KDHLLSISLSGYINYLDKN---NPSKPLRVIKG---HSKSIQCLTVHRNGGKSYIYSGSH 342
           KD+LL   +SG  +   K    +  K L+ + G   H  ++ CL  +    K ++ + S 
Sbjct: 549 KDNLL---VSGNADSTVKVWDVHTGKCLQTLLGPNKHRSAVTCLQFN----KKFVVTCSD 707

Query: 343 DGHINYWDSETGE----NDSFSGKGHTNQVSRMTVNESEQLVSCSMDDTVRYTNLTLRDY 398
           DG +  WD  TG+      +    G    V R+  N ++ + +    +    T L + D+
Sbjct: 708 DGTVKLWDLNTGDFIRNLITLPSGGSGGVVWRLRCNNTKMVCAVGSRNGTEETKLLVLDF 887
>00561
          Length = 1003

 Score = 50.8 bits (120), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 54/215 (25%), Positives = 94/215 (43%), Gaps = 8/215 (3%)
 Frame = -3

Query: 57  HAHQVVVAKYAPSGFYIASGDISGKLRIWDTTQKEHLLKYEYQPFAGKIKD---IAWTED 113
           H+H +     +  G Y  SG     LR+WD    +   ++E     G  KD   +A++ D
Sbjct: 869 HSHFISDVVLSSDGNYALSGSWDQTLRLWDLAAGKTTRRFE-----GHTKDVLSVAFSAD 705

Query: 114 SKRIAVVGEGREKFGAVFLWDTGSSVG---EITGHNKVINSVDI--KQTRPYRLATGSDD 168
           +++I  V   R+K   + LW+T +      +  GH   ++ V      + P  ++ G D 
Sbjct: 704 NRQI--VSGSRDK--TIKLWNTLAECKFTIQEDGHTDWVSCVRFSPNHSNPIIVSCGWDR 537

Query: 169 NCAAFFEGPPFKFKFTIGDHSRFVNCVRFSPDGNRFATASADGQIFIYDGKTGEKVCALG 228
                +     K K     H+ ++N V  SPDG+   +   D +  ++D   G+ +  L 
Sbjct: 536 T-VKVWNLANCKLKNNHHGHNGYLNTVTVSPDGSLCTSGGKDSKALLWDLNDGKNLYTL- 363

Query: 229 ESKAHDGGIYAISWSPDSTHLLSASGDKTSKIWDV 263
               H+  I A+ +SP+   L  A G  + KIWD+
Sbjct: 362 ---EHNDIINALCFSPNRYWLCVAYG-PSIKIWDL 270

 Score = 42.0 bits (97), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 48/186 (25%), Positives = 77/186 (41%), Gaps = 17/186 (9%)
 Frame = -3

Query: 188 HSRFVNCVRFSPDGNRFATASADGQIFIYD---GKTGEKVCALGESKAHDGGIYAISWSP 244
           HS F++ V  S DGN   + S D  + ++D   GKT  +       + H   + ++++S 
Sbjct: 869 HSHFISDVVLSSDGNYALSGSWDQTLRLWDLAAGKTTRRF------EGHTKDVLSVAFSA 708

Query: 245 DSTHLLSASGDKTSKIWDVNVN--------------SVVSTFPMGSNVLDQQLGCLWQKD 290
           D+  ++S S DKT K+W+                  S V   P  SN +   + C W + 
Sbjct: 707 DNRQIVSGSRDKTIKLWNTLAECKFTIQEDGHTDWVSCVRFSPNHSNPI--IVSCGWDR- 537

Query: 291 HLLSISLSGYINYLDKNNPSKPLRVIKGHSKSIQCLTVHRNGGKSYIYSGSHDGHINYWD 350
              ++ +    N   KNN         GH+  +  +TV  +G  S   SG  D     WD
Sbjct: 536 ---TVKVWNLANCKLKNN-------HHGHNGYLNTVTVSPDG--SLCTSGGKDSKALLWD 393

Query: 351 SETGEN 356
              G+N
Sbjct: 392 LNDGKN 375

 Score = 41.6 bits (96), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 38/140 (27%), Positives = 64/140 (45%), Gaps = 7/140 (5%)
 Frame = -3

Query: 132 LWD--TGSSVGEITGHNKVINSVDIKQTRPYRLATGSDDNCAAFFEGPPFKFKFTIGD-- 187
           LWD   G +     GH K + SV        ++ +GS D     +     + KFTI +  
Sbjct: 788 LWDLAAGKTTRRFEGHTKDVLSVAFSADN-RQIVSGSRDKTIKLWNTL-AECKFTIQEDG 615

Query: 188 HSRFVNCVRFSPDGNRFATASA--DGQIFIYDGKTGEKVCALGES-KAHDGGIYAISWSP 244
           H+ +V+CVRFSP+ +     S   D  + +++       C L  +   H+G +  ++ SP
Sbjct: 614 HTDWVSCVRFSPNHSNPIIVSCGWDRTVKVWNLAN----CKLKNNHHGHNGYLNTVTVSP 447

Query: 245 DSTHLLSASGDKTSKIWDVN 264
           D +   S   D  + +WD+N
Sbjct: 446 DGSLCTSGGKDSKALLWDLN 387

 Score = 39.7 bits (91), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 30/86 (34%), Positives = 42/86 (48%), Gaps = 3/86 (3%)
 Frame = -3

Query: 311 KPLRVIKGHSKSIQCLTVHRNGGKSYIYSGSHDGHINYWDSETGENDSFSGKGHTNQVS- 369
           K  R  +GH+K +  L+V  +     I SGS D  I  W++      +    GHT+ VS 
Sbjct: 767 KTTRRFEGHTKDV--LSVAFSADNRQIVSGSRDKTIKLWNTLAECKFTIQEDGHTDWVSC 594

Query: 370 -RMTVNESEQ-LVSCSMDDTVRYTNL 393
            R + N S   +VSC  D TV+  NL
Sbjct: 593 VRFSPNHSNPIIVSCGWDRTVKVWNL 516

 Score = 35.4 bits (80), Expect = 0.070,   Method: Compositional matrix adjust.
 Identities = 19/66 (28%), Positives = 33/66 (50%)
 Frame = -3

Query: 498 SHDGAFLAVCDASKVVTVFSVADGYSENNVFYGHHAKIVCLAWSPDNEHFASGGMDMMVY 557
           +H    +  C   + V V+++A+   +NN  +GH+  +  +  SPD     SGG D    
Sbjct: 578 NHSNPIIVSCGWDRTVKVWNLANCKLKNN-HHGHNGYLNTVTVSPDGSLCTSGGKDSKAL 402

Query: 558 VWTLSD 563
           +W L+D
Sbjct: 401 LWDLND 384

 Score = 29.3 bits (64), Expect = 4.9,   Method: Compositional matrix adjust.
 Identities = 12/38 (31%), Positives = 21/38 (55%)
 Frame = -2

Query: 230 SKAHDGGIYAISWSPDSTHLLSASGDKTSKIWDVNVNS 267
           SKA      +++WS D   L +   D T ++W V+V++
Sbjct: 219 SKAEQPQCLSLAWSTDGQTLFAGYSDNTIRVWQVSVSA 106

 Score = 28.9 bits (63), Expect = 6.8,   Method: Compositional matrix adjust.
 Identities = 22/82 (26%), Positives = 37/82 (45%)
 Frame = -3

Query: 521 GYSENNVFYGHHAKIVCLAWSPDNEHFASGGMDMMVYVWTLSDPETKVKIQDAHRLHHVS 580
           GY +  + YGH   I  +  S D  +  SG  D  + +W L+  +T  + +  H    +S
Sbjct: 896 GYPQKRL-YGHSHFISDVVLSSDGNYALSGSWDQTLRLWDLAAGKTTRRFE-GHTKDVLS 723

Query: 581 SLAWLDEHTLVTTSHDASVKEW 602
                D   +V+ S D ++K W
Sbjct: 722 VAFSADNRQIVSGSRDKTIKLW 657
>03387
          Length = 1891

 Score = 50.4 bits (119), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 54/205 (26%), Positives = 83/205 (40%), Gaps = 23/205 (11%)
 Frame = +1

Query: 187 DHSRFVNCVRFSPDGN-RFATASADGQIFIYD--------GKTGEKVCALGESKAHDGGI 237
           +H   VN  R+ P      AT +    + ++D          +GE +  L   K H    
Sbjct: 196 NHEGEVNRARYMPQNPCIIATKTPSSDVLVFDYTKHPSKPDPSGECIPEL-RLKGHQKEG 372

Query: 238 YAISWSPD-STHLLSASGDKTSKIWDVNVNSVVSTFPMGSNVLDQQLGCL----WQKDHL 292
           Y +SW+P+ + HLLSAS D T  +WD+N     S       +       +    W   HL
Sbjct: 373 YGLSWNPNLNGHLLSASDDHTICLWDINSTQRESRVVDAHTIFTGHTSVVEDVAW---HL 543

Query: 293 LSISLSGYINYLDK--------NNPSKPLRVIKGHSKSIQCLTVHRNGGKSYIY-SGSHD 343
           L  SL G +    K        N  SKP  V+  H+  + CL+   N    +I  +GS D
Sbjct: 544 LHESLFGSVADDQKLMIWDTRSNTTSKPSHVVDAHTAEVNCLSF--NPYSEFILATGSAD 717

Query: 344 GHINYWDSETGENDSFSGKGHTNQV 368
             +  WD    +    S + H +++
Sbjct: 718 KTVALWDLRNLKLKLHSFESHKDEI 792
>03395
          Length = 2795

 Score = 47.8 bits (112), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 48/191 (25%), Positives = 87/191 (45%), Gaps = 9/191 (4%)
 Frame = +2

Query: 192 VNCVRFSPDGNRFATASADGQIFIYD-------GKTGEKVCALGESKAHDGGIYAISWSP 244
           V  +  +  G +  +   +GQ+ ++D       GKT   + A    K H G + AI    
Sbjct: 5   VTAIAVTSCGTKLVSGGGEGQVRVWDIVKDMLTGKTRGDLVA--NMKEHKGKVTAIQIHT 178

Query: 245 DSTHLLSASGDKTSKIWDVNVNSVVSTFPMGSNVLDQQLGCLWQKD-HLLSISLSGYINY 303
           +    +SAS D ++ IWD+  N+        +N L + + C   KD H+L+      I Y
Sbjct: 179 NDRCCVSASTDGSTIIWDLITNTRSQIVL--ANTLFKCV-CFGGKDLHILTSGTDHKIGY 349

Query: 304 LDKNNPSKPLRVIKG-HSKSIQCLTVHRNGGKSYIYSGSHDGHINYWDSETGENDSFSGK 362
            +  +    LR ++G  + +I  + + R+G    I +G  D  +  W    GE  + +G 
Sbjct: 350 WEVGDGG-LLRELEGSQTGAINTIDIDRDG--QTILTGGEDSLLKLWRYNEGEV-THTGI 517

Query: 363 GHTNQVSRMTV 373
           GH+NQ+++  +
Sbjct: 518 GHSNQITKARI 550
>02147
          Length = 1547

 Score = 47.8 bits (112), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 61/334 (18%), Positives = 116/334 (34%), Gaps = 1/334 (0%)
 Frame = +2

Query: 227 LGESKAHDGGIYAISWSPDSTHLLSASGDKTSKIWDVNVNSVVSTFPMGSNVLDQQLGCL 286
           +G  + H G ++  + + ++T   + + D ++KIWD      + TF              
Sbjct: 152 IGTFEGHKGAVWGATLNREATRAATGAADFSAKIWDAEKGEELQTF-------------- 289

Query: 287 WQKDHLLSISLSGYINYLDKNNPSKPLRVIKGHSKSIQCLTVHRNGGKSYIYSGSHDGHI 346
                                           H   ++ +    +G  + + +GS++  +
Sbjct: 290 -------------------------------SHKHIVKSVDFSHDG--TALLTGSNEKLL 370

Query: 347 NYWDSETGENDSFSGKGHTNQVS-RMTVNESEQLVSCSMDDTVRYTNLTLRDYSGQGVVK 405
             +D    + +  S  GHT+ +   + +++ ++++S S D TVR  +L       Q  + 
Sbjct: 371 KVFDLVNTDAEPKSFAGHTSNIKGALFLSDGKRIISASDDKTVRLWSLETCQEVQQ--LT 544

Query: 406 LDVQPKCVAVGPGGYTVVVCIGQIVLLKDQKKCFSIDNPGYEPEVVAVHPXXXXXXXXXX 465
            D  P  + + P   T++V   Q                                     
Sbjct: 545 FDTPPTSLTLSPDKNTIIVTHSQ------------------------------------- 613

Query: 466 XXNVRVYSILASTLKDEGKLLEAKGPVTDVAYSHDGAFLAVCDASKVVTVFSVADGYSEN 525
             N+  Y   A TL+ E K  EA+ P++  +      F         +  F    G  E 
Sbjct: 614 --NIAFYQ--ADTLR-EMKKFEAEAPISSASLHQSERFFVAGGEDFKMYKFDYETG-KEI 775

Query: 526 NVFYGHHAKIVCLAWSPDNEHFASGGMDMMVYVW 559
             F GH   + C+ +SPD E +ASG  D  + +W
Sbjct: 776 ESFKGHFGPVHCVRFSPDGELYASGSEDGTLRLW 877

 Score = 37.4 bits (85), Expect = 0.016,   Method: Compositional matrix adjust.
 Identities = 24/80 (30%), Positives = 37/80 (46%), Gaps = 7/80 (8%)
 Frame = +2

Query: 149 INSVDIKQTRPYRLATGSDDNCAAFFEGPPFKFKFTIGD-------HSRFVNCVRFSPDG 201
           I+S  + Q+  + +A G D           +KF +  G        H   V+CVRFSPDG
Sbjct: 677 ISSASLHQSERFFVAGGEDFKM--------YKFDYETGKEIESFKGHFGPVHCVRFSPDG 832

Query: 202 NRFATASADGQIFIYDGKTG 221
             +A+ S DG + ++    G
Sbjct: 833 ELYASGSEDGTLRLWQTTIG 892

 Score = 35.8 bits (81), Expect = 0.053,   Method: Compositional matrix adjust.
 Identities = 49/234 (20%), Positives = 89/234 (38%), Gaps = 42/234 (17%)
 Frame = +2

Query: 74  ASGDISGKLRIWDTTQKEHLLKYEYQPFAGKIKDIAWTEDSKRIAVVGEGREKFGAVF-L 132
           A+G      +IWD  + E L  + ++     +K + ++ D    A++    EK   VF L
Sbjct: 221 ATGAADFSAKIWDAEKGEELQTFSHKHI---VKSVDFSHDG--TALLTGSNEKLLKVFDL 385

Query: 133 WDTGSSVGEITGHN-------------KVINSVDIKQTRPYRLATGSDDNCAAFFEGPPF 179
            +T +      GH              ++I++ D K  R + L T  +     F + PP 
Sbjct: 386 VNTDAEPKSFAGHTSNIKGALFLSDGKRIISASDDKTVRLWSLETCQEVQQLTF-DTPPT 562

Query: 180 KFKFT------IGDHSRFVNCVRFSPDGNR----------------------FATASADG 211
               +      I  HS+  N   +  D  R                      F     D 
Sbjct: 563 SLTLSPDKNTIIVTHSQ--NIAFYQADTLREMKKFEAEAPISSASLHQSERFFVAGGEDF 736

Query: 212 QIFIYDGKTGEKVCALGESKAHDGGIYAISWSPDSTHLLSASGDKTSKIWDVNV 265
           +++ +D +TG+++ +    K H G ++ + +SPD     S S D T ++W   +
Sbjct: 737 KMYKFDYETGKEIESF---KGHFGPVHCVRFSPDGELYASGSEDGTLRLWQTTI 889
>19498
          Length = 903

 Score = 47.8 bits (112), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 42/173 (24%), Positives = 69/173 (39%), Gaps = 32/173 (18%)
 Frame = -1

Query: 121 GEGREKFGAVFLW--------------DTGSSVGEITGHNKVINSVDIKQTRPYRLATGS 166
           G+G    G V +W              D    + ++  H   +N V   +   + LA+G 
Sbjct: 903 GQGEGDSGKVVIWNMAPIRDEKEEADDDVPRVLCQMDSHLGCVNCVRWSENGKF-LASGG 727

Query: 167 DDNCAAFFE-------GPPFKFKFTIGDHSRFVNCVR----------FSPDGNRFATASA 209
           DD     ++       G  F    TI +H R V  +R          +SP     A+ S 
Sbjct: 726 DDKLIMIWQISRGFGSGKSFGSNVTILEHWRSVATLRGHAGDVLDLAWSPQDLWLASCSV 547

Query: 210 DGQIFIYDG-KTGEKVCALGESKAHDGGIYAISWSPDSTHLLSASGDKTSKIW 261
           D  I +++  K  E+V  +   + H G +  ++W P   +L S S DKT ++W
Sbjct: 546 DNTIVVWNALKFSEQVAVI---RGHAGMVKGVTWDPVGRYLASQSDDKTLRVW 397

 Score = 43.9 bits (102), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 31/110 (28%), Positives = 47/110 (42%), Gaps = 4/110 (3%)
 Frame = -1

Query: 490 GPVTDVAYSHDGAFLAVCDASKVVTVFSVADGYSENNVFYGHHAKIVCLAWSPDNEHFAS 549
           G V D+A+S    +LA C     + V++      +  V  GH   +  + W P   + AS
Sbjct: 606 GDVLDLAWSPQDLWLASCSVDNTIVVWNALKFSEQVAVIRGHAGMVKGVTWDPVGRYLAS 427

Query: 550 GGMDMMVYVWTLSD--PETKVK--IQDAHRLHHVSSLAWLDEHTLVTTSH 595
              D  + VW  SD   ET VK   ++     HV  L W  +   V ++H
Sbjct: 426 QSDDKTLRVWRTSDWKEETCVKSCFKECGGTTHVLRLNWSPDGNHVVSAH 277

 Score = 39.7 bits (91), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 25/101 (24%), Positives = 41/101 (40%), Gaps = 16/101 (15%)
 Frame = -1

Query: 490 GPVTDVAYSHDGAFLAVCDASKVVTVFSVADGYSENNVF----------------YGHHA 533
           G V  V +S +G FLA     K++ ++ ++ G+     F                 GH  
Sbjct: 783 GCVNCVRWSENGKFLASGGDDKLIMIWQISRGFGSGKSFGSNVTILEHWRSVATLRGHAG 604

Query: 534 KIVCLAWSPDNEHFASGGMDMMVYVWTLSDPETKVKIQDAH 574
            ++ LAWSP +   AS  +D  + VW       +V +   H
Sbjct: 603 DVLDLAWSPQDLWLASCSVDNTIVVWNALKFSEQVAVIRGH 481

 Score = 39.3 bits (90), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 25/89 (28%), Positives = 37/89 (41%), Gaps = 14/89 (15%)
 Frame = -1

Query: 188 HSRFVNCVRFSPDGNRFATASADGQIFIYDGKTG--------------EKVCALGESKAH 233
           H   VNCVR+S +G   A+   D  I I+    G              E   ++   + H
Sbjct: 789 HLGCVNCVRWSENGKFLASGGDDKLIMIWQISRGFGSGKSFGSNVTILEHWRSVATLRGH 610

Query: 234 DGGIYAISWSPDSTHLLSASGDKTSKIWD 262
            G +  ++WSP    L S S D T  +W+
Sbjct: 609 AGDVLDLAWSPQDLWLASCSVDNTIVVWN 523

 Score = 34.3 bits (77), Expect = 0.16,   Method: Compositional matrix adjust.
 Identities = 45/204 (22%), Positives = 84/204 (41%), Gaps = 30/204 (14%)
 Frame = -1

Query: 79  SGKLRIWDTT----QKEHL------LKYEYQPFAGKIKDIAWTEDSKRIAVVGEGR---- 124
           SGK+ IW+      +KE        +  +     G +  + W+E+ K +A  G+ +    
Sbjct: 885 SGKVVIWNMAPIRDEKEEADDDVPRVLCQMDSHLGCVNCVRWSENGKFLASGGDDKLIMI 706

Query: 125 ----------EKFGA-VFLWDTGSSVGEITGHNKVINSVDIKQT-RPYRLATGSDDNCAA 172
                     + FG+ V + +   SV  + GH    + +D+  + +   LA+ S DN   
Sbjct: 705 WQISRGFGSGKSFGSNVTILEHWRSVATLRGHAG--DVLDLAWSPQDLWLASCSVDNTIV 532

Query: 173 FFEGPPFKFKFT-IGDHSRFVNCVRFSPDGNRFATASADGQIFIYDGKTGEKVCALGESK 231
            +    F  +   I  H+  V  V + P G   A+ S D  + ++     ++   +    
Sbjct: 531 VWNALKFSEQVAVIRGHAGMVKGVTWDPVGRYLASQSDDKTLRVWRTSDWKEETCVKSCF 352

Query: 232 AHDGG---IYAISWSPDSTHLLSA 252
              GG   +  ++WSPD  H++SA
Sbjct: 351 KECGGTTHVLRLNWSPDGNHVVSA 280

 Score = 31.6 bits (70), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 42/167 (25%), Positives = 63/167 (37%), Gaps = 22/167 (13%)
 Frame = -1

Query: 227 LGESKAHDGGIYAISWSPDSTHLLSASGDKTSKIWDVNVNSVVSTFPMGSNVLDQQ---- 282
           L +  +H G +  + WS +   L S   DK   IW ++     S    GSNV   +    
Sbjct: 807 LCQMDSHLGCVNCVRWSENGKFLASGGDDKLIMIWQIS-RGFGSGKSFGSNVTILEHWRS 631

Query: 283 -----------LGCLW--QKDHLLSISLSGYINYLDKNNPSKPLRVIKGHSKSIQCLTVH 329
                      L   W  Q   L S S+   I   +    S+ + VI+GH+  ++ +T  
Sbjct: 630 VATLRGHAGDVLDLAWSPQDLWLASCSVDNTIVVWNALKFSEQVAVIRGHAGMVKGVTWD 451

Query: 330 RNGGKSYIYSGSHDGHINYWDS-----ETGENDSFSGKGHTNQVSRM 371
             G   Y+ S S D  +  W +     ET     F   G T  V R+
Sbjct: 450 PVG--RYLASQSDDKTLRVWRTSDWKEETCVKSCFKECGGTTHVLRL 316

 Score = 30.8 bits (68), Expect = 1.7,   Method: Compositional matrix adjust.
 Identities = 11/32 (34%), Positives = 19/32 (59%)
 Frame = -1

Query: 531 HHAKIVCLAWSPDNEHFASGGMDMMVYVWTLS 562
           H   + C+ WS + +  ASGG D ++ +W +S
Sbjct: 789 HLGCVNCVRWSENGKFLASGGDDKLIMIWQIS 694
>02960
          Length = 1577

 Score = 47.4 bits (111), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 34/127 (26%), Positives = 60/127 (47%), Gaps = 1/127 (0%)
 Frame = +2

Query: 139  VGEITGHNKVINSVDIKQTRPYRLATGSDDNCAAFFEGPPFKFKFTIGDHSRFVNCVRFS 198
            V  ++GH + +++V  +   P+R+ T S D+    ++    + + ++   S+ V  V +S
Sbjct: 938  VLTLSGHAEAVSAV--RWLDPHRVVTSSWDHSLRLWDLHTAQ-QTSLIQGSKAVLDVAYS 1108

Query: 199  PDGNRFATASADGQIFIYDGKTGEKVCALGESKAHDGGIYAISWSPDSTHL-LSASGDKT 257
            P  +   T SAD  + + D +  E         +H G +  + WSP   HL LS S D  
Sbjct: 1109 PLSHMLITGSADRHVRLVDPRCSEGETVKCAFTSHTGWVTGVDWSPTREHLFLSGSYDNV 1288

Query: 258  SKIWDVN 264
             K+WD  
Sbjct: 1289 LKLWDTR 1309

 Score = 41.2 bits (95), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 60/275 (21%), Positives = 106/275 (38%), Gaps = 11/275 (4%)
 Frame = +2

Query: 311 KPLRVIKGHSKSIQCLTVHR---NGGKSYIYSGSHD--GHINYWDSETGENDS-FSGKGH 364
           + +  I GH+  ++C+   +   + G S   +GSHD    +  W  ET E D   S +GH
Sbjct: 575 EAIMTIPGHTSPVKCVAWIKHDESSGVSTFVTGSHDQTALVWQWQRETNEVDCRLSCRGH 754

Query: 365 TNQVSRMTVN-ESEQLVSCSMDDTVRYTNLTLRDYSGQGVVKLDVQPKCVAVGPGGYTVV 423
              V  + V+ +S+Q+ + S D  ++   L   D +  G    D +           T  
Sbjct: 755 AASVDCVAVSPDSQQMCTGSWDKMLK---LWSTDCNVDGDQSEDTERPSKKKKSAKSTTQ 925

Query: 424 VCIGQIVLLKDQKKCFSIDNPGYEPEVVAVHPXXXXXXXXXX-XXNVRVYSILASTLKDE 482
             +  + L             G+   V AV               ++R++ +  +    +
Sbjct: 926 TRVPVLTL------------SGHAEAVSAVRWLDPHRVVTSSWDHSLRLWDLHTA---QQ 1060

Query: 483 GKLLEAKGPVTDVAYSHDGAFLAVCDASKVVTVF--SVADGYSENNVFYGHHAKIVCLAW 540
             L++    V DVAYS     L    A + V +     ++G +    F  H   +  + W
Sbjct: 1061TSLIQGSKAVLDVAYSPLSHMLITGSADRHVRLVDPRCSEGETVKCAFTSHTGWVTGVDW 1240

Query: 541 SPDNEH-FASGGMDMMVYVWTLSDPETKVKIQDAH 574
           SP  EH F SG  D ++ +W    P+  +   + H
Sbjct: 1241SPTREHLFLSGSYDNVLKLWDTRSPKATLYDMNWH 1345

 Score = 40.8 bits (94), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 64/300 (21%), Positives = 118/300 (39%), Gaps = 43/300 (14%)
 Frame = +2

Query: 130 VFLWDT-GSSVGEITGHNKVINSVD-IKQTRPYRLAT---GSDDNCAAFF----EGPPFK 180
           V LW T G ++  I GH   +  V  IK      ++T   GS D  A  +    E     
Sbjct: 551 VRLWSTKGEAIMTIPGHTSPVKCVAWIKHDESSGVSTFVTGSHDQTALVWQWQRETNEVD 730

Query: 181 FKFTIGDHSRFVNCVRFSPDGNRFATASADGQIFIY------DGKTGE------------ 222
            + +   H+  V+CV  SPD  +  T S D  + ++      DG   E            
Sbjct: 731 CRLSCRGHAASVDCVAVSPDSQQMCTGSWDKMLKLWSTDCNVDGDQSEDTERPSKKKKSA 910

Query: 223 ------KVCALGESKAHDGGIYAISWSPDSTHLLSASGDKTSKIWDVNVNSVVSTFPMGS 276
                 +V  L  S  H   + A+ W  D   ++++S D + ++WD++     S      
Sbjct: 911 KSTTQTRVPVLTLS-GHAEAVSAVRWL-DPHRVVTSSWDHSLRLWDLHTAQQTSLIQGSK 1084

Query: 277 NVLDQQLGCLWQKDHLLSISLSGYINYLDKNNPSKPLRVIKGHSKSIQCLTVHRNG---- 332
            VLD     L     L++ S   ++  +D        R  +G  ++++C      G    
Sbjct: 1085AVLDVAYSPL--SHMLITGSADRHVRLVDP-------RCSEG--ETVKCAFTSHTGWVTG 1231

Query: 333 -----GKSYIY-SGSHDGHINYWDSETGENDSFSGKGHTNQVSRMTVNESEQLVSCSMDD 386
                 + +++ SGS+D  +  WD+ + +   +    H +++  +  +  E L+S  +D+
Sbjct: 1232VDWSPTREHLFLSGSYDNVLKLWDTRSPKATLYDMNWHEDRILAVDWSIPELLLSGGVDN 1411

 Score = 38.9 bits (89), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 26/99 (26%), Positives = 43/99 (43%), Gaps = 24/99 (24%)
 Frame = +2

Query: 530 GHHAKIVCLAWSPDNEHFASGGMDMMVYVWTLSDPETKVKIQDAHR-------------- 575
           GH A + C+A SPD++   +G  D M+ +W+        + +D  R              
Sbjct: 749 GHAASVDCVAVSPDSQQMCTGSWDKMLKLWSTDCNVDGDQSEDTERPSKKKKSAKSTTQT 928

Query: 576 ----------LHHVSSLAWLDEHTLVTTSHDASVKEWTI 604
                        VS++ WLD H +VT+S D S++ W +
Sbjct: 929 RVPVLTLSGHAEAVSAVRWLDPHRVVTSSWDHSLRLWDL 1045
>15337
          Length = 860

 Score = 46.6 bits (109), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 45/214 (21%), Positives = 81/214 (37%), Gaps = 2/214 (0%)
 Frame = -1

Query: 58  AHQVVVAKYAPSGFYIASGDISGKLRIWDTTQKEHLLKYEYQPFAGKIK--DIAWTEDSK 115
            H       +P    +  G  +G++++ D  +KE    Y  +    K K   I W   S 
Sbjct: 680 CHDFNATTVSPESVLLLVGFTAGQVQLIDPIKKEISKLYNEERLIDKTKVTCIKWVPGSG 501

Query: 116 RIAVVGEGREKFGAVFLWDTGSSVGEITGHNKVINSVDIKQTRPYRLATGSDDNCAAFFE 175
              +V  G    G ++ ++     G+        N    KQ   Y + T    +      
Sbjct: 500 NQFLVSHGS---GQMYAYNEELPCGQTPP-----NYQPFKQGEGYSVFTCKTKST----R 357

Query: 176 GPPFKFKFTIGDHSRFVNCVRFSPDGNRFATASADGQIFIYDGKTGEKVCALGESKAHDG 235
            P +++    G  S F     FSP     A    DG + +++  + E    +G  K++ G
Sbjct: 356 NPLYRWVVGTGAISEFA----FSPCSRYLAVVGQDGHLRVFNYNSME---LIGTMKSYFG 198

Query: 236 GIYAISWSPDSTHLLSASGDKTSKIWDVNVNSVV 269
           G+  + WSPD  ++++   D    +W  +   VV
Sbjct: 197 GLLCVCWSPDGKYIVTGGEDDLVTVWSFHEKRVV 96

 Score = 38.1 bits (87), Expect = 0.009,   Method: Compositional matrix adjust.
 Identities = 19/74 (25%), Positives = 37/74 (50%)
 Frame = -1

Query: 490 GPVTDVAYSHDGAFLAVCDASKVVTVFSVADGYSENNVFYGHHAKIVCLAWSPDNEHFAS 549
           G +++ A+S    +LAV      + VF+  +          +   ++C+ WSPD ++  +
Sbjct: 326 GAISEFAFSPCSRYLAVVGQDGHLRVFNY-NSMELIGTMKSYFGGLLCVCWSPDGKYIVT 150

Query: 550 GGMDMMVYVWTLSD 563
           GG D +V VW+  +
Sbjct: 149 GGEDDLVTVWSFHE 108
>01768
          Length = 1424

 Score = 45.4 bits (106), Expect = 6e-05,   Method: Compositional matrix adjust.
 Identities = 30/87 (34%), Positives = 47/87 (54%), Gaps = 3/87 (3%)
 Frame = +3

Query: 182 KFTIGDHSRFVNCVRFSP-DGNRFATASADGQIFIYDGKTG-EKVCALGESKAHDGGIYA 239
           K +   H+  V  V++SP +GN FA+ S D  + I++ +    K   L   +AH   I  
Sbjct: 816 KSSYAAHTDSVEDVQWSPNEGNVFASCSVDRTLRIWNTQQKPSKANVLTVPEAHSRDINV 995

Query: 240 ISWSPDSTHLLSASGDK-TSKIWDVNV 265
           I+W+P   HLL++ GD    KIWD+ +
Sbjct: 996 INWNPIEKHLLASGGDDGIIKIWDLRM 1076

 Score = 42.4 bits (98), Expect = 6e-04,   Method: Compositional matrix adjust.
 Identities = 26/82 (31%), Positives = 44/82 (53%), Gaps = 4/82 (4%)
 Frame = +3

Query: 188  HSRFVNCVRFSP-DGNRFATASADGQIFIYDGKT--GEKVCALGESKAHDGGIYAISWSP 244
            HSR +N + ++P + +  A+   DG I I+D +    + V A    K H   + ++ W+P
Sbjct: 975  HSRDINVINWNPIEKHLLASGGDDGIIKIWDLRMFRNKPVSAQASFKLHSQPVTSLEWNP 1154

Query: 245  DSTHLLSASG-DKTSKIWDVNV 265
              + +L+ASG D    IWD +V
Sbjct: 1155 QDSSVLAASGEDDQITIWDFSV 1220

 Score = 32.7 bits (73), Expect = 0.39,   Method: Compositional matrix adjust.
 Identities = 37/171 (21%), Positives = 59/171 (34%), Gaps = 7/171 (4%)
 Frame = +3

Query: 54  YTEHAHQVVVAKYAPS-GFYIASGDISGKLRIWDTTQKEHLLKYEYQPFAGKIKDIAWTE 112
           Y  H   V   +++P+ G   AS  +   LRIW+T QK                      
Sbjct: 825 YAAHTDSVEDVQWSPNEGNVFASCSVDRTLRIWNTQQK---------------------P 941

Query: 113 DSKRIAVVGEGREKFGAVFLWDTGSSVGEITGHNKVINSVDIKQTRPYRLATGSDDNCAA 172
               +  V E                      H++ IN ++      + LA+G DD    
Sbjct: 942 SKANVLTVPE---------------------AHSRDINVINWNPIEKHLLASGGDDGIIK 1058

Query: 173 -----FFEGPPFKFKFTIGDHSRFVNCVRFSP-DGNRFATASADGQIFIYD 217
                 F   P   + +   HS+ V  + ++P D +  A +  D QI I+D
Sbjct: 1059IWDLRMFRNKPVSAQASFKLHSQPVTSLEWNPQDSSVLAASGEDDQITIWD 1211
>31384
          Length = 474

 Score = 45.1 bits (105), Expect = 8e-05,   Method: Compositional matrix adjust.
 Identities = 23/81 (28%), Positives = 43/81 (53%), Gaps = 3/81 (3%)
 Frame = -1

Query: 192 VNCVRFSP---DGNRFATASADGQIFIYDGKTGEKVCALGESKAHDGGIYAISWSPDSTH 248
           V+C++FSP         + S D ++  ++ +   +     + + H G +  + WS D T 
Sbjct: 267 VSCLKFSPGALPSTFLISGSWDNKVSCWEVQQSGQTIPKAQ-QTHTGPVLDVDWSDDGTK 91

Query: 249 LLSASGDKTSKIWDVNVNSVV 269
           + +AS DKT+K+WD+N N  +
Sbjct: 90  VFTASCDKTAKVWDLNSNQCM 28

 Score = 30.8 bits (68), Expect = 1.7,   Method: Compositional matrix adjust.
 Identities = 14/50 (28%), Positives = 23/50 (46%)
 Frame = -1

Query: 68  PSGFYIASGDISGKLRIWDTTQKEHLLKYEYQPFAGKIKDIAWTEDSKRI 117
           PS F I SG    K+  W+  Q    +    Q   G + D+ W++D  ++
Sbjct: 234 PSTFLI-SGSWDNKVSCWEVQQSGQTIPKAQQTHTGPVLDVDWSDDGTKV 88
>12806
          Length = 961

 Score = 45.1 bits (105), Expect = 8e-05,   Method: Compositional matrix adjust.
 Identities = 57/223 (25%), Positives = 96/223 (43%), Gaps = 17/223 (7%)
 Frame = +3

Query: 157 TRPYRLATGSDDNCAAF------------FEGPPFKFKFTIGDHSRFVNCVRFSPDGNRF 204
           T+P+ ++ G D+N   +              G P K   T+  HS F++ +  S D +RF
Sbjct: 42  TKPFLISGGRDNNIIVWDL*PKKDGDEDQTWGVPRK---TLTGHSHFISDLALSAD-SRF 209

Query: 205 ATASA-DGQIFIYDGKTGEKVCALGESKAHDGGIYAISWSPDSTHLLSASGDKTSKIWDV 263
           A +S+ D  + ++D K G           H   +  +++SPD+  + S   DK  KIW++
Sbjct: 210 ALSSSWDATLRLWDIKKGSTTSRFIN---HTRDVLTVAFSPDNRQIASGGRDKNLKIWNI 380

Query: 264 NVNSVVSTFPMGSNVLDQQLGCL-WQKDHLLSISLSGYINYLDK--NNPSKPLR-VIKGH 319
                   + + +N     + C+ + +D    I +S   +   K  +N +  L+    GH
Sbjct: 381 MGE---CKYTVDANAHTDWVTCVRFHQDTKNPIVVSASNDKTIKVWDNHTMTLKNTFVGH 551

Query: 320 SKSIQCLTVHRNGGKSYIYSGSHDGHINYWDSETGENDSFSGK 362
              I  L +  N    Y+ SGS DG    W+   G   SF GK
Sbjct: 552 KAQITALDMSTN----YLVSGSKDGIAMTWNVAEG---SFVGK 659

 Score = 41.2 bits (95), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 20/70 (28%), Positives = 35/70 (50%)
 Frame = +3

Query: 492 VTDVAYSHDGAFLAVCDASKVVTVFSVADGYSENNVFYGHHAKIVCLAWSPDNEHFASGG 551
           ++D+A S D  F         + ++ +  G S  + F  H   ++ +A+SPDN   ASGG
Sbjct: 174 ISDLALSADSRFALSSSWDATLRLWDIKKG-STTSRFINHTRDVLTVAFSPDNRQIASGG 350

Query: 552 MDMMVYVWTL 561
            D  + +W +
Sbjct: 351 RDKNLKIWNI 380

 Score = 33.9 bits (76), Expect = 0.21,   Method: Compositional matrix adjust.
 Identities = 41/175 (23%), Positives = 70/175 (40%), Gaps = 9/175 (5%)
 Frame = +3

Query: 54  YTEHAHQVVVAKYAPSGFYIASGDISGKLRIWDTTQKEHLLKYEYQPFAGK--IKDIAWT 111
           +  H   V+   ++P    IASG     L+IW+   +    KY     A    +  + + 
Sbjct: 279 FINHTRDVLTVAFSPDNRQIASGGRDKNLKIWNIMGE---CKYTVDANAHTDWVTCVRFH 449

Query: 112 EDSKRIAVVGEGREKFGAVFLWD--TGSSVGEITGHNKVINSVDIKQTRPYRLATGSDDN 169
           +D+K   VV    +K   + +WD  T +      GH   I ++D+       L +GS D 
Sbjct: 450 QDTKNPIVVSASNDK--TIKVWDNHTMTLKNTFVGHKAQITALDMSTN---YLVSGSKDG 614

Query: 170 CAAFFEGPPFKFKFTIGDHSRFVNCVRFSPDGNR-----FATASADGQIFIYDGK 219
            A  +      F   I D    +N ++F+ + N+     F       QI+ Y G+
Sbjct: 615 IAMTWNVAEGSFVGKI-DCDDQINAIKFNIENNKKKVWLFIGTQNGIQIWDYSGE 776
>31474
          Length = 403

 Score = 45.1 bits (105), Expect = 9e-05,   Method: Composition-based stats.
 Identities = 26/75 (34%), Positives = 39/75 (52%), Gaps = 1/75 (1%)
 Frame = -3

Query: 188 HSRFVNCVRFSPDGNRFATASADGQIFIYDGKTGEK-VCALGESKAHDGGIYAISWSPDS 246
           H     CV ++P G   A+  +D  I I+ GK G+  VC    + AH   + ++ WSP  
Sbjct: 308 HDEHAWCVAWNPTGTLLASCGSDKIIKIW-GKEGDNWVCKSTLTDAHTRTVRSLGWSPCG 132

Query: 247 THLLSASGDKTSKIW 261
            +L SAS D T+ +W
Sbjct: 131 NYLSSASFDATTAVW 87

 Score = 35.4 bits (80), Expect = 0.070,   Method: Composition-based stats.
 Identities = 18/42 (42%), Positives = 23/42 (54%)
 Frame = -3

Query: 220 TGEKVCALGESKAHDGGIYAISWSPDSTHLLSASGDKTSKIW 261
           T E+VC L    AHD   + ++W+P  T L S   DK  KIW
Sbjct: 338 TLEEVCCL---SAHDEHAWCVAWNPTGTLLASCGSDKIIKIW 222

 Score = 33.1 bits (74), Expect = 0.35,   Method: Composition-based stats.
 Identities = 23/77 (29%), Positives = 33/77 (42%), Gaps = 3/77 (3%)
 Frame = -3

Query: 530 GHHAKIVCLAWSPDNEHFASGGMDMMVYVWTLSDPE--TKVKIQDAHRLHHVSSLAWLD- 586
            H     C+AW+P     AS G D ++ +W         K  + DAH    V SL W   
Sbjct: 311 AHDEHAWCVAWNPTGTLLASCGSDKIIKIWGKEGDNWVCKSTLTDAHT-RTVRSLGWSPC 135

Query: 587 EHTLVTTSHDASVKEWT 603
            + L + S DA+   W+
Sbjct: 134 GNYLSSASFDATTAVWS 84
>17598
          Length = 875

 Score = 44.3 bits (103), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 60/265 (22%), Positives = 98/265 (36%), Gaps = 5/265 (1%)
 Frame = +1

Query: 182 KFTIGDHSRFVNCVRFSPDGNRFATASADGQIFIYDGKTGEKVCALGESKAHDGGIYAIS 241
           + T+  HS FV+ V  S D     ++S D  + ++D K G          +H     A++
Sbjct: 100 RRTLQGHSHFVSDVSLSADSRYVLSSSWDATLRLWDIKKGNTTRRF---ISHTRDALAVA 270

Query: 242 WSPDSTHLLSASGDKTSKIWDVNVNSV-VSTFPMGSNVLDQQLGCLWQKDHLLSISLSGY 300
           +SPD+  + S   DK  KIW    N+V    F + +N                       
Sbjct: 271 FSPDNRQIASGGRDKALKIW----NTVGECKFTVDAN----------------------- 369

Query: 301 INYLDKNNPSKPLRVIKGHSKSIQCLTVHRNGGKSYIYSGSHDGHINYWDSETGENDSFS 360
                             H   + C+  H++     + S S D  I  WD++T      +
Sbjct: 370 -----------------SHQDWVTCVKFHQDAKSPLVVSASMDKTIKVWDNQT-MTLKHT 495

Query: 361 GKGHTNQVSRMTVN-ESEQLVSCSMDDTVRYTNLTLRDYSGQGVVKLDVQPKCVAVGPGG 419
             GH  Q++ + +  ++  L S S D  V   N+    + G+  +  D +   V   P  
Sbjct: 496 FVGHKTQINAIDLALKTYYLASGSKDGIVMTWNIQNGTFLGK--IDCDCEVNAVKFSPNK 669

Query: 420 YTVVVCIG---QIVLLKDQKKCFSI 441
           Y + V      QI  L +QKK   I
Sbjct: 670 YWLFVGTSEGIQIWDLPNQKKIKDI 744

 Score = 43.9 bits (102), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 44/173 (25%), Positives = 75/173 (43%), Gaps = 2/173 (1%)
 Frame = +1

Query: 54  YTEHAHQVVVAKYAPSGFYIASGDISGKLRIWDTTQKEHLLKYEYQPFAGKIKDIAWTED 113
           +  H    +   ++P    IASG     L+IW+T   E     +       +  + + +D
Sbjct: 235 FISHTRDALAVAFSPDNRQIASGGRDKALKIWNTV-GECKFTVDANSHQDWVTCVKFHQD 411

Query: 114 SKRIAVVGEGREKFGAVFLWDTGSSVGEIT--GHNKVINSVDIKQTRPYRLATGSDDNCA 171
           +K   VV    +K   + +WD  +   + T  GH   IN++D+   + Y LA+GS D   
Sbjct: 412 AKSPLVVSASMDK--TIKVWDNQTMTLKHTFVGHKTQINAIDL-ALKTYYLASGSKDGIV 582

Query: 172 AFFEGPPFKFKFTIGDHSRFVNCVRFSPDGNRFATASADGQIFIYDGKTGEKV 224
             +      F   I D    VN V+FSP+       +++G I I+D    +K+
Sbjct: 583 MTWNIQNGTFLGKI-DCDCEVNAVKFSPNKYWLFVGTSEG-IQIWDLPNQKKI 735

 Score = 38.1 bits (87), Expect = 0.009,   Method: Compositional matrix adjust.
 Identities = 19/68 (27%), Positives = 33/68 (48%)
 Frame = +1

Query: 492 VTDVAYSHDGAFLAVCDASKVVTVFSVADGYSENNVFYGHHAKIVCLAWSPDNEHFASGG 551
           V+DV+ S D  ++        + ++ +  G +    F  H    + +A+SPDN   ASGG
Sbjct: 130 VSDVSLSADSRYVLSSSWDATLRLWDIKKGNTTRR-FISHTRDALAVAFSPDNRQIASGG 306

Query: 552 MDMMVYVW 559
            D  + +W
Sbjct: 307 RDKALKIW 330

 Score = 37.0 bits (84), Expect = 0.025,   Method: Compositional matrix adjust.
 Identities = 48/217 (22%), Positives = 88/217 (40%), Gaps = 10/217 (4%)
 Frame = +1

Query: 57  HAHQVVVAKYAPSGFYIASGDISGKLRIWDTTQKEHLLKYEYQPFAGKIKD---IAWTED 113
           H+H V     +    Y+ S      LR+WD  +         + F    +D   +A++ D
Sbjct: 118 HSHFVSDVSLSADSRYVLSSSWDATLRLWDIKKGN-----TTRRFISHTRDALAVAFSPD 282

Query: 114 SKRIAVVGEGREKFGAVFLWDTGSSVGEI------TGHNKVINSVDIKQ-TRPYRLATGS 166
           +++IA    GR+K  A+ +W+T   VGE         H   +  V   Q  +   + + S
Sbjct: 283 NRQIA--SGGRDK--ALKIWNT---VGECKFTVDANSHQDWVTCVKFHQDAKSPLVVSAS 441

Query: 167 DDNCAAFFEGPPFKFKFTIGDHSRFVNCVRFSPDGNRFATASADGQIFIYDGKTGEKVCA 226
            D     ++      K T   H   +N +  +      A+ S DG +  ++ + G     
Sbjct: 442 MDKTIKVWDNQTMTLKHTFVGHKTQINAIDLALKTYYLASGSKDGIVMTWNIQNG---TF 612

Query: 227 LGESKAHDGGIYAISWSPDSTHLLSASGDKTSKIWDV 263
           LG+    D  + A+ +SP+   L   + +   +IWD+
Sbjct: 613 LGKIDC-DCEVNAVKFSPNKYWLFVGTSEGI-QIWDL 717
>33180
          Length = 460

 Score = 42.7 bits (99), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 23/90 (25%), Positives = 46/90 (51%), Gaps = 1/90 (1%)
 Frame = -2

Query: 187 DHSRFVNCVRFSPDGNRFATASADGQIFIYDGKTGEKVCALGESKAHDGGIYAISWSPDS 246
           +HS  +  + FS D       + DG +++YD ++ ++   +    AHD  + A++++ DS
Sbjct: 459 EHSFCIFSLMFSSDNTEIVGGANDGCLYVYDRESNQRTLKI---DAHDDDVNAVAFADDS 289

Query: 247 THLLSASGDK-TSKIWDVNVNSVVSTFPMG 275
           + +L + GD    K+WD       +  P+G
Sbjct: 288 SQILYSGGDDGLCKVWDRRTLREDNPLPVG 199
>26107
          Length = 1338

 Score = 42.0 bits (97), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 37/151 (24%), Positives = 58/151 (38%), Gaps = 30/151 (19%)
 Frame = -3

Query: 232  AHDGGIYAISWSPDSTHLLSASGDKTSKIWDVNVNSVVSTFPMGSNVLDQQLGCLWQKDH 291
            AH+  ++  SW  + +  L+ASGD+T  +WDV   + V+TF      +     C      
Sbjct: 1093 AHNNAVFDYSWISNDSQCLTASGDQTVALWDVETTTKVTTFIGHKCSVRSVASCPSSPAQ 914

Query: 292  LLSISLSGYINYLD----KNNPSKPLRVI------KGH-SKSIQCLTVHRNGGKS----- 335
              S +  G+I   D    K    +P   +       GH SK  +   +HR  G       
Sbjct: 913  CASGARDGHIMLWDSRVNKKREHQPCSQVHQVCPQSGHQSKPAKHRRIHRAAGPKGVMDT 734

Query: 336  --------------YIYSGSHDGHINYWDSE 352
                           I SG++DG +  WD+ 
Sbjct: 733  QQSVTCVLYQTDNLIISSGANDGCVKMWDTR 641

 Score = 29.3 bits (64), Expect = 5.1,   Method: Compositional matrix adjust.
 Identities = 48/229 (20%), Positives = 84/229 (36%), Gaps = 16/229 (6%)
 Frame = -3

Query: 63  VAKYAPSGFYIASGDISGKLRIWDTTQKEHLLKYEYQPFAGKIKDIAWTEDSKRIAVVGE 122
           VA    S    ASG   G + +WD+   +   K E+QP +   +    +    + A    
Sbjct: 943 VASCPSSPAQCASGARDGHIMLWDSRVNK---KREHQPCSQVHQVCPQSGHQSKPAKHRR 773

Query: 123 GREKFGAVFLWDTGSSVGEITGHNKVINSVDIKQTRPYRLATGSDDNCAAFFEG------ 176
                G   + DT  SV  +           + QT    +++G++D C   ++       
Sbjct: 772 IHRAAGPKGVMDTQQSVTCV-----------LYQTDNLIISSGANDGCVKMWDTRKWYTN 626

Query: 177 -----PPFKFKFTIGDHSRFVN---CVRFSPDGNRFATASADGQIFIYD--GKTGEKVCA 226
                P     F    H R +     +   P  ++   +  D +++ Y   G+  E    
Sbjct: 625 TTTSLPVPVHTFDYPGHMRRLKGIVTMCMDPWKSQLFVSYTDNKVYRYQLAGQYREPQEY 446

Query: 227 LGESKAHDGGIYAISWSPDSTHLLSASGDKTSKIWDVNVNSVVSTFPMG 275
           +     +D      + SPD  +LLS SG  T  IW+V+  +    F +G
Sbjct: 445 VYAGHRNDTFFVRCAISPDGKYLLSGSGRNTGVIWEVDKPNKRPLFLIG 299
>38177
          Length = 430

 Score = 41.6 bits (96), Expect = 0.001,   Method: Composition-based stats.
 Identities = 21/75 (28%), Positives = 39/75 (52%)
 Frame = +3

Query: 194 CVRFSPDGNRFATASADGQIFIYDGKTGEKVCALGESKAHDGGIYAISWSPDSTHLLSAS 253
           C+ ++P+G R  T ++ G+  +++G T      L   +AHD  + A+ WS     +++A 
Sbjct: 3   CLAWTPEGRRLVTGASSGEFTLWNGLTFNFETIL---QAHDVSVRAMRWSNHDQWMVTAD 173

Query: 254 GDKTSKIWDVNVNSV 268
                K W  N+N+V
Sbjct: 174 HSGYIKYWQSNMNNV 218

 Score = 29.3 bits (64), Expect = 5.2,   Method: Composition-based stats.
 Identities = 17/69 (24%), Positives = 30/69 (43%), Gaps = 3/69 (4%)
 Frame = +3

Query: 537 CLAWSPDNEHFASGGMDMMVYVWT--LSDPETKVKIQDAHRLHHVSSLAWLD-EHTLVTT 593
           CLAW+P+     +G       +W     + ET ++  D      V ++ W + +  +VT 
Sbjct: 3   CLAWTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDV----SVRAMRWSNHDQWMVTA 170

Query: 594 SHDASVKEW 602
            H   +K W
Sbjct: 171 DHSGYIKYW 197
>01598
          Length = 1545

 Score = 40.0 bits (92), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 45/187 (24%), Positives = 71/187 (37%), Gaps = 32/187 (17%)
 Frame = +1

Query: 118  AVVGEGREKFGAVFLWDTGSSVGEITGHNKVINSVDIKQTRPYRLATGSDDNCAAFFEGP 177
            AV+  G +K  A+          +IT     +NS  +K  +   L+   D N AA     
Sbjct: 889  AVLSRGEKKANAI----------DITQKIGAVNSDQVKGLKATELSWSPDQNAAAVGTDE 1038

Query: 178  PFKFKFTIGD---------HSRFVNCVRF-----------SPDGNRFATASADGQIFIYD 217
               +  TI D           + +NCVR+           SP  +  A A  D  I + D
Sbjct: 1039 GSVYVVTIQDLKIVAAIRTQQKLINCVRWHPRLTDQSPAGSPCCHWLAAAGNDQVIHVVD 1218

Query: 218  ------GKTGEK-----VCALGESKAHDGGIYAISWSP-DSTHLLSASGDKTSKIWDVNV 265
                   + G+K     + +L E   H   +  +SWSP     L+S   D  + +WDV  
Sbjct: 1219 LASVFAEREGDKETSLILTSLRELSGHSQRVTDMSWSPHHDARLVSVGYDAEAFVWDVQK 1398

Query: 266  NSVVSTF 272
             + ++ F
Sbjct: 1399 GTALAQF 1419

 Score = 31.2 bits (69), Expect = 1.4,   Method: Compositional matrix adjust.
 Identities = 22/102 (21%), Positives = 43/102 (42%), Gaps = 8/102 (7%)
 Frame = +1

Query: 512  VVTVFSVADGYSENNVFY-------GHHAKIVCLAWSPDNE-HFASGGMDMMVYVWTLSD 563
            + +VF+  +G  E ++         GH  ++  ++WSP ++    S G D   +VW +  
Sbjct: 1219 LASVFAEREGDKETSLILTSLRELSGHSQRVTDMSWSPHHDARLVSVGYDAEAFVWDVQK 1398

Query: 564  PETKVKIQDAHRLHHVSSLAWLDEHTLVTTSHDASVKEWTIT 605
                 + +           + LD   ++T   DASV  W ++
Sbjct: 1399 GTALAQFKGHMGRLLTCQFSGLDPDLVMTGGSDASVHVWRVS 1524
>29912
          Length = 510

 Score = 39.7 bits (91), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 39/189 (20%), Positives = 70/189 (37%), Gaps = 3/189 (1%)
 Frame = +3

Query: 70  GFYIASGDISGKLRIWDTTQKEHLLKYEYQPFAGKIKDIAWTEDSKRIAVVGEGREKFGA 129
           G Y+A G  +G++++WD TQ++ L        A ++  ++W                   
Sbjct: 45  GNYLALGTSTGEVQVWDVTQQKKLRTMAGH--AARVGSLSWNS----------------- 167

Query: 130 VFLWDTGSSVGEITGHNKVINSVDIKQTRPYRLATGSDDNCAAFFEGPPFKFKFTIGDHS 189
            F+  +GS  G I  H+  +    +                             T+  HS
Sbjct: 168 -FIVSSGSRSGNIHHHDVRVADHHVG----------------------------TLSGHS 260

Query: 190 RFVNCVRFSPDGNRFATASADGQIFIYDGKT--GEKVCALGESKAHDGGIYAISWSP-DS 246
           + V  +R+SPDG   A+ + D  + ++  +   G     L     H   + A++W P   
Sbjct: 261 QEVCGLRWSPDGKYLASGANDNLLCVWPAQVTGGNSTQPLHTFSQHQAAVKALAWCPWQP 440

Query: 247 THLLSASGD 255
           + L S  GD
Sbjct: 441 SXLASGGGD 467

 Score = 33.1 bits (74), Expect = 0.33,   Method: Compositional matrix adjust.
 Identities = 13/30 (43%), Positives = 19/30 (63%)
 Frame = +3

Query: 530 GHHAKIVCLAWSPDNEHFASGGMDMMVYVW 559
           GH  ++  L WSPD ++ ASG  D ++ VW
Sbjct: 252 GHSQEVCGLRWSPDGKYLASGANDNLLCVW 341

 Score = 31.6 bits (70), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 33/140 (23%), Positives = 53/140 (37%), Gaps = 7/140 (5%)
 Frame = +3

Query: 162 LATGSDDNCAAFFEGPPFKFKFTIGDHSRFVNCVRFSPDGNRF--ATASADGQIFIYDGK 219
           LA G+       ++    K   T+  H+  V  + +    N F  ++ S  G I  +D +
Sbjct: 54  LALGTSTGEVQVWDVTQQKKLRTMAGHAARVGSLSW----NSFIVSSGSRSGNIHHHDVR 221

Query: 220 TGEKVCALGESKAHDGGIYAISWSPDSTHLLSASGDKTSKIWDVNVNSVVSTFPMGSNVL 279
             +    +G    H   +  + WSPD  +L S + D    +W   V    ST P+ +   
Sbjct: 222 VADH--HVGTLSGHSQEVCGLRWSPDGKYLASGANDNLLCVWPAQVTGGNSTQPLHTFSQ 395

Query: 280 DQQ-----LGCLWQKDHLLS 294
            Q        C WQ   L S
Sbjct: 396 HQAAVKALAWCPWQPSXLAS 455

 Score = 30.4 bits (67), Expect = 2.1,   Method: Compositional matrix adjust.
 Identities = 31/124 (25%), Positives = 56/124 (45%), Gaps = 2/124 (1%)
 Frame = +3

Query: 237 IYAISWSPDSTHLLSASGDKTSKIWDVNVNSVVSTFPMGSNVLDQQLGCL-WQKDHLLSI 295
           I A+SW  +  +L   +     ++WDV     + T    +     ++G L W    + S 
Sbjct: 18  IGAVSWIKEGNYLALGTSTGEVQVWDVTQQKKLRTMAGHA----ARVGSLSWNSFIVSSG 185

Query: 296 SLSGYINYLDKNNPSKPLRVIKGHSKSIQCLTVHRNGGKSYIYSGSHDGHINYWDSE-TG 354
           S SG I++ D       +  + GHS+ +  L    +G   Y+ SG++D  +  W ++ TG
Sbjct: 186 SRSGNIHHHDVRVADHHVGTLSGHSQEVCGLRWSPDG--KYLASGANDNLLCVWPAQVTG 359

Query: 355 ENDS 358
            N +
Sbjct: 360 GNST 371
>27465
          Length = 658

 Score = 38.9 bits (89), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 23/94 (24%), Positives = 42/94 (44%), Gaps = 2/94 (2%)
 Frame = -1

Query: 132 LWDTGSS--VGEITGHNKVINSVDIKQTRPYRLATGSDDNCAAFFEGPPFKFKFTIGDHS 189
           +WDT S+  +  + GH  V+ ++        ++ TGS D     +     K   T+  H+
Sbjct: 283 IWDTASAEELHTLEGHRNVVYAIAFNNPFGDKVITGSFDKTCKLWSTADGKCYHTLRGHT 104

Query: 190 RFVNCVRFSPDGNRFATASADGQIFIYDGKTGEK 223
             + CV F+P     AT S D    ++D +  ++
Sbjct: 103 AEIVCVSFNPSSTLIATGSMDTTCRLWDVEKAQR 2

 Score = 32.7 bits (73), Expect = 0.43,   Method: Compositional matrix adjust.
 Identities = 29/131 (22%), Positives = 53/131 (40%), Gaps = 5/131 (3%)
 Frame = -1

Query: 231 KAHDGGIYAISWSPDSTHLLSASGDKTSKIWDVNVNSVVSTFPMGSNVL-----DQQLGC 285
           +AH   +  ++++   +  ++ S D+T KIWD      + T     NV+     +   G 
Sbjct: 370 RAHILPLTNVAFNKSGSSFITGSYDRTCKIWDTASAEELHTLEGHRNVVYAIAFNNPFG- 194

Query: 286 LWQKDHLLSISLSGYINYLDKNNPSKPLRVIKGHSKSIQCLTVHRNGGKSYIYSGSHDGH 345
               D +++ S       L      K    ++GH+  I C++   N   + I +GS D  
Sbjct: 193 ----DKVITGSFDKTCK-LWSTADGKCYHTLRGHTAEIVCVSF--NPSSTLIATGSMDTT 35

Query: 346 INYWDSETGEN 356
              WD E  + 
Sbjct: 34  CRLWDVEKAQR 2
>25930
          Length = 419

 Score = 38.9 bits (89), Expect = 0.006,   Method: Composition-based stats.
 Identities = 20/60 (33%), Positives = 31/60 (51%), Gaps = 1/60 (1%)
 Frame = +1

Query: 205 ATASADGQIFIYDGKTGE-KVCALGESKAHDGGIYAISWSPDSTHLLSASGDKTSKIWDV 263
           A  S  G I IYD +    ++  +  S   D  I  ++WS D+T L+S S   T ++WD+
Sbjct: 106 AVGSVRGDILIYDVRLEPWRLARIAPSNGQDDSIKNLNWSLDATRLISVSESGTLQVWDL 285
>13278
          Length = 870

 Score = 38.5 bits (88), Expect = 0.009,   Method: Compositional matrix adjust.
 Identities = 22/69 (31%), Positives = 40/69 (57%)
 Frame = +1

Query: 204 FATASADGQIFIYDGKTGEKVCALGESKAHDGGIYAISWSPDSTHLLSASGDKTSKIWDV 263
            A+AS D  + +++ + G  +C    +K H   +Y++++SPD  +L S S DK   IW+V
Sbjct: 121 LASASFDSTVRLWEVERG--LCLHTLTK-HQEPVYSVAFSPDGKYLASGSFDKCVHIWNV 291

Query: 264 NVNSVVSTF 272
              S+V ++
Sbjct: 292 QTGSLVHSY 318

 Score = 30.0 bits (66), Expect = 2.7,   Method: Compositional matrix adjust.
 Identities = 21/95 (22%), Positives = 37/95 (38%)
 Frame = +1

Query: 40  VILRNIDNPAIADIYTEHAHQVVVAKYAPSGFYIASGDISGKLRIWDTTQKEHLLKYEYQ 99
           V L  ++        T+H   V    ++P G Y+ASG     + IW+      +  Y+  
Sbjct: 148 VRLWEVERGLCLHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNVQTGSLVHSYK-- 321

Query: 100 PFAGKIKDIAWTEDSKRIAVVGEGREKFGAVFLWD 134
              G I ++ W     ++          G+VF+ D
Sbjct: 322 -GTGGIFEVCWNHRGDKVGASASD----GSVFVLD 411

 Score = 30.0 bits (66), Expect = 3.1,   Method: Compositional matrix adjust.
 Identities = 11/31 (35%), Positives = 19/31 (61%)
 Frame = +1

Query: 531 HHAKIVCLAWSPDNEHFASGGMDMMVYVWTL 561
           H   +  +A+SPD ++ ASG  D  V++W +
Sbjct: 199 HQEPVYSVAFSPDGKYLASGSFDKCVHIWNV 291
>19863
          Length = 502

 Score = 38.1 bits (87), Expect = 0.011,   Method: Compositional matrix adjust.
 Identities = 20/64 (31%), Positives = 34/64 (53%)
 Frame = +1

Query: 200 DGNRFATASADGQIFIYDGKTGEKVCALGESKAHDGGIYAISWSPDSTHLLSASGDKTSK 259
           DG +  + S+D  I ++D + G +   L   + H G +  + +S D   LLS S D T +
Sbjct: 4   DGLQLVSGSSDMSIVVWDVENGVQKLRL---QGHAGWVNDVHFSQDQCWLLSCSNDNTVR 174

Query: 260 IWDV 263
           IW++
Sbjct: 175 IWNI 186

 Score = 32.3 bits (72), Expect = 0.56,   Method: Compositional matrix adjust.
 Identities = 22/62 (35%), Positives = 32/62 (51%), Gaps = 1/62 (1%)
 Frame = +1

Query: 337 IYSGSHDGHINYWDSETGENDSFSGKGHTNQVSRMTVNESE-QLVSCSMDDTVRYTNLTL 395
           + SGS D  I  WD E G       +GH   V+ +  ++ +  L+SCS D+TVR  N+  
Sbjct: 16  LVSGSSDMSIVVWDVENGVQ-KLRLQGHAGWVNDVHFSQDQCWLLSCSNDNTVRIWNIEE 192

Query: 396 RD 397
            D
Sbjct: 193 SD 198
>01805
          Length = 2124

 Score = 37.7 bits (86), Expect = 0.015,   Method: Compositional matrix adjust.
 Identities = 20/82 (24%), Positives = 35/82 (42%), Gaps = 1/82 (1%)
 Frame = -1

Query: 142 ITGHNKVINSVDIKQTRPYRLATGSDDNCAAFFEGPPFKFKFTIGDHSRFVNCVRFSPDG 201
           +TGH + +  +   +   + LA+ S D   A ++    K       HSR V C  + P  
Sbjct: 588 VTGHTQAVLDLSWNRNARHVLASASADTTVALWDLSEGKMAMNFTQHSREVQCCNWHPQE 409

Query: 202 NR-FATASADGQIFIYDGKTGE 222
            +   T S D  + + D ++ E
Sbjct: 408 EQTLLTGSFDNTVKVVDCRSAE 343

 Score = 28.9 bits (63), Expect = 6.0,   Method: Compositional matrix adjust.
 Identities = 14/45 (31%), Positives = 24/45 (53%), Gaps = 1/45 (2%)
 Frame = -1

Query: 233 HDGGIYAISWSPDSTHLL-SASGDKTSKIWDVNVNSVVSTFPMGS 276
           H   +  +SW+ ++ H+L SAS D T  +WD++   +   F   S
Sbjct: 579 HTQAVLDLSWNRNARHVLASASADTTVALWDLSEGKMAMNFTQHS 445
>17266
          Length = 480

 Score = 37.0 bits (84), Expect = 0.022,   Method: Compositional matrix adjust.
 Identities = 27/105 (25%), Positives = 47/105 (44%), Gaps = 3/105 (2%)
 Frame = -1

Query: 162 LATGSDDNCAAFFEGPPFKFKFTIGDHSRFVNCVRFSPDGNRFATASADGQIFIYDGKTG 221
             +G+ D  A  ++      K T   H   +N + + P+G+ FAT S D    ++D +  
Sbjct: 414 FVSGACDASAKLWDVRDGMCKQTFSGHESDINAITYFPNGHAFATGSDDATCRLFDIRAD 235

Query: 222 EKVCALGESKAHDG---GIYAISWSPDSTHLLSASGDKTSKIWDV 263
           +++       +HD    GI ++++S     LL    D    IWDV
Sbjct: 234 QEI----GMYSHDNIICGITSVAFSKSGRLLLGGYDDFNCNIWDV 112

 Score = 35.0 bits (79), Expect = 0.085,   Method: Compositional matrix adjust.
 Identities = 35/157 (22%), Positives = 67/157 (42%), Gaps = 5/157 (3%)
 Frame = -1

Query: 195 VRFSPDGNRFATASADGQIFIYDGKTGEKVCALGESKAHDGGIYAISWSPDSTHLLSASG 254
           +  +PD   F + + D    ++D + G  +C    S  H+  I AI++ P+     + S 
Sbjct: 441 LSLAPDMRTFVSGACDASAKLWDVRDG--MCKQTFS-GHESDINAITYFPNGHAFATGSD 271

Query: 255 DKTSKIWDVNVNSVVSTFPMGSNVLDQQLGCLWQKDHLLSISLSGYINYLDKNNPSKPLR 314
           D T +++D+  +  +  +   + +         +   LL   L GY ++    N    L+
Sbjct: 270 DATCRLFDIRADQEIGMYSHDNIICGITSVAFSKSGRLL---LGGYDDF--NCNIWDVLK 106

Query: 315 -----VIKGHSKSIQCLTVHRNGGKSYIYSGSHDGHI 346
                V+ GH   + CL V  +G  S + +GS D  +
Sbjct: 105 QERTGVLAGHDNRVSCLGVTEDG--SAVATGSWDSFL 1
>27806
          Length = 419

 Score = 37.0 bits (84), Expect = 0.025,   Method: Compositional matrix adjust.
 Identities = 22/58 (37%), Positives = 30/58 (51%)
 Frame = -1

Query: 204 FATASADGQIFIYDGKTGEKVCALGESKAHDGGIYAISWSPDSTHLLSASGDKTSKIW 261
             TASAD    IY  +TG  V   G    H G + A+ + P    +L+ASGD T+ +W
Sbjct: 380 IGTASADHTARIYSIETGACVLTYG---GHQGSVNAVRFHPGQDLVLTASGDHTAHVW 216

 Score = 30.0 bits (66), Expect = 2.7,   Method: Compositional matrix adjust.
 Identities = 19/66 (28%), Positives = 28/66 (42%), Gaps = 2/66 (3%)
 Frame = -1

Query: 153 DIKQTRPYR--LATGSDDNCAAFFEGPPFKFKFTIGDHSRFVNCVRFSPDGNRFATASAD 210
           ++  +RP    + T S D+ A  +         T G H   VN VRF P  +   TAS D
Sbjct: 413 EVSVSRPGHPIIGTASADHTARIYSIETGACVLTYGGHQGSVNAVRFHPGQDLVLTASGD 234

Query: 211 GQIFIY 216
               ++
Sbjct: 233 HTAHVW 216
>15780
          Length = 735

 Score = 36.6 bits (83), Expect = 0.027,   Method: Compositional matrix adjust.
 Identities = 20/60 (33%), Positives = 32/60 (53%)
 Frame = -1

Query: 204 FATASADGQIFIYDGKTGEKVCALGESKAHDGGIYAISWSPDSTHLLSASGDKTSKIWDV 263
            +TA AD  + ++D  +G  V  L    AH   +YA+ +S D T L S   D + ++WD+
Sbjct: 729 LSTAGADHTVIVWDIASGTAVAHL---TAHTDTVYALCFSRDGTVLASGGMDNSIRLWDL 559

 Score = 33.5 bits (75), Expect = 0.23,   Method: Compositional matrix adjust.
 Identities = 22/74 (29%), Positives = 34/74 (45%), Gaps = 6/74 (8%)
 Frame = -1

Query: 503 FLAVCDASKVVTVFSVADGYSENNVFYGHHAKIVCLAWSPDNEHFASGGMDMMVYVWTLS 562
           +L+   A   V V+ +A G +  +    H   +  L +S D    ASGGMD  + +W L+
Sbjct: 732 YLSTAGADHTVIVWDIASGTAVAH-LTAHTDTVYALCFSRDGTVLASGGMDNSIRLWDLA 556

Query: 563 ------DPETKVKI 570
                 DPET   +
Sbjct: 555 RVMEEQDPETDSNV 514
>27525
          Length = 828

 Score = 36.6 bits (83), Expect = 0.031,   Method: Compositional matrix adjust.
 Identities = 45/171 (26%), Positives = 70/171 (40%), Gaps = 25/171 (14%)
 Frame = +2

Query: 192 VNCVRFSPDGNRFATASADGQIFIY----DGKT-GEKVCALGESKAHDGGIYAISWSPDS 246
           +N + FSPDG++ A    DG + +Y    DG    +K  AL   + +   I  + WS D 
Sbjct: 77  INAISFSPDGSQLAVGCHDGFVHVYVVHEDGLVFRQKSAAL---RYNSTFIMHLDWSSDC 247

Query: 247 THLLSASGDKTSKIWDV------------NVNSVVSTFPMGS----NVLDQQLGCLWQKD 290
            +L    GD     W+V            +VN    + P+G      + D   G      
Sbjct: 248 RYLQCTLGDYELVFWEVQNMKKQSGRALRDVNWSTFSSPVGYPPCWALADD--GARGSDQ 421

Query: 291 HLLSISLSG-YINY-LDKNNPSK--PLRVIKGHSKSIQCLTVHRNGGKSYI 337
           H LS+ +   Y N    ++NP+   P   +KG     Q L V  N G+ ++
Sbjct: 422 HGLSLQIPXLYPNR*QQRSNPTLQIPFHWLKGGMSGNQALLVKHNSGRDFV 574
>30295
          Length = 593

 Score = 36.6 bits (83), Expect = 0.033,   Method: Composition-based stats.
 Identities = 17/47 (36%), Positives = 26/47 (55%)
 Frame = +2

Query: 231 KAHDGGIYAISWSPDSTHLLSASGDKTSKIWDVNVNSVVSTFPMGSN 277
           + H   IYA+ W+ DS +L+SAS D    +WD    + V   P+ S+
Sbjct: 236 RXHLAKIYAMHWATDSRNLVSASQDGKLIVWDGYTTNKVHAIPLRSS 376

 Score = 29.6 bits (65), Expect = 4.0,   Method: Composition-based stats.
 Identities = 24/101 (23%), Positives = 37/101 (36%)
 Frame = +2

Query: 162 LATGSDDNCAAFFEGPPFKFKFTIGDHSRFVNCVRFSPDGNRFATASADGQIFIYDGKTG 221
           L + S D     ++G        I   S +V    ++P G   A    D    IY  KT 
Sbjct: 290 LVSASQDGKLIVWDGYTTNKVHAIPLRSSWVMTCAYAPSGGYVACGGLDNICSIYSLKTR 469

Query: 222 EKVCALGESKAHDGGIYAISWSPDSTHLLSASGDKTSKIWD 262
           E    +        G  +     D   ++++SGD T  +WD
Sbjct: 470 EGNVRVSRELPGHTGYLSCCRFIDDNQIVTSSGDMTCALWD 592

 Score = 28.9 bits (63), Expect = 6.1,   Method: Composition-based stats.
 Identities = 13/44 (29%), Positives = 24/44 (54%)
 Frame = +2

Query: 184 TIGDHSRFVNCVRFSPDGNRFATASADGQIFIYDGKTGEKVCAL 227
           T+  H   +  + ++ D     +AS DG++ ++DG T  KV A+
Sbjct: 230 TLRXHLAKIYAMHWATDSRNLVSASQDGKLIVWDGYTTNKVHAI 361
>01327
          Length = 2215

 Score = 36.2 bits (82), Expect = 0.040,   Method: Compositional matrix adjust.
 Identities = 28/125 (22%), Positives = 52/125 (41%)
 Frame = +3

Query: 155 KQTRPYRLATGSDDNCAAFFEGPPFKFKFTIGDHSRFVNCVRFSPDGNRFATASADGQIF 214
           +  +P    +GS D     ++    + +     H R +  V +    N   +AS D  I 
Sbjct: 63  RSIQPGLCLSGSKDKSVVLYDYQNGRLEDRWTGHDREITKVCYGASCNGMFSASRDKTIK 242

Query: 215 IYDGKTGEKVCALGESKAHDGGIYAISWSPDSTHLLSASGDKTSKIWDVNVNSVVSTFPM 274
           ++         ++ +   HD  + AI  + D+T L S S D T +IWDV   + +    +
Sbjct: 243 MWQRGNSH---SIRDFIGHDMVVTAIHLNTDNTLLCSGSRDNTVRIWDVETGACLRQNNI 413

Query: 275 GSNVL 279
             N++
Sbjct: 414 PQNLV 428

 Score = 30.4 bits (67), Expect = 2.2,   Method: Compositional matrix adjust.
 Identities = 30/113 (26%), Positives = 50/113 (44%), Gaps = 4/113 (3%)
 Frame = +3

Query: 492 VTDVAY--SHDGAFLAVCDASKVVTVFSVADGYSENNVFYGHHAKIVCLAWSPDNEHFAS 549
           +T V Y  S +G F A  D  K + ++   + +S  + F GH   +  +  + DN    S
Sbjct: 174 ITKVCYGASCNGMFSASRD--KTIKMWQRGNSHSIRD-FIGHDMVVTAIHLNTDNTLLCS 344

Query: 550 GGMDMMVYVWTLSDPETKVKI-QDAHRLHHVSSLAWL-DEHTLVTTSHDASVK 600
           G  D  V +W   D ET   + Q+    + V+ + WL   H ++    D  V+
Sbjct: 345 GSRDNTVRIW---DVETGACLRQNNIPQNLVTDVKWLPGSHLIIQAGEDKEVR 494

 Score = 30.0 bits (66), Expect = 2.9,   Method: Compositional matrix adjust.
 Identities = 31/149 (20%), Positives = 46/149 (30%)
 Frame = +3

Query: 206 TASADGQIFIYDGKTGEKVCALGESKAHDGGIYAISWSPDSTHLLSASGDKTSKIWDVNV 265
           + S D  + +YD + G           HD  I  + +      + SAS DKT K+W    
Sbjct: 90  SGSKDKSVVLYDYQNGR---LEDRWTGHDREITKVCYGASCNGMFSASRDKTIKMW---- 248

Query: 266 NSVVSTFPMGSNVLDQQLGCLWQKDHLLSISLSGYINYLDKNNPSKPLRVIKGHSKSIQC 325
                                                   +   S  +R   GH   +  
Sbjct: 249 ----------------------------------------QRGNSHSIRDFIGHDMVVT- 305

Query: 326 LTVHRNGGKSYIYSGSHDGHINYWDSETG 354
             +H N   + + SGS D  +  WD ETG
Sbjct: 306 -AIHLNTDNTLLCSGSRDNTVRIWDVETG 389
>14555
          Length = 627

 Score = 35.4 bits (80), Expect = 0.059,   Method: Compositional matrix adjust.
 Identities = 19/55 (34%), Positives = 25/55 (45%)
 Frame = -2

Query: 170 CAAFFEGPPFKFKFTIGDHSRFVNCVRFSPDGNRFATASADGQIFIYDGKTGEKV 224
           C   FEG           H   +NCVRF P G+ FAT S D    ++D +   +V
Sbjct: 623 CVQMFEG-----------HEADINCVRFYPSGDAFATGSDDATCRLFDLRADREV 492

 Score = 33.1 bits (74), Expect = 0.37,   Method: Compositional matrix adjust.
 Identities = 19/62 (30%), Positives = 28/62 (45%), Gaps = 5/62 (8%)
 Frame = -3

Query: 503 FLAVCDASKVVT---VFSVADGYS--ENNVFYGHHAKIVCLAWSPDNEHFASGGMDMMVY 557
           FL+V D    VT     +V D      + + YGH  ++ CL  SPD     +G  D  + 
Sbjct: 442 FLSVVDCCLGVTNDYTVNVWDALKGMRSTILYGHDNRVSCLRISPDGTSLCTGSWDYTLR 263

Query: 558 VW 559
           +W
Sbjct: 262 IW 257
>01462
          Length = 995

 Score = 35.4 bits (80), Expect = 0.069,   Method: Compositional matrix adjust.
 Identities = 20/72 (27%), Positives = 41/72 (56%), Gaps = 1/72 (1%)
 Frame = +2

Query: 323 IQCLTVHRNGGKSYIYSGSHDGHINYWDSETGENDSFSGKGHTNQVSRMTV-NESEQLVS 381
           +  + V    G   +Y+G+ D  I+ WD E G+  + + +GH + + ++ + N++++ VS
Sbjct: 200 VNSIAVDEKMGTRRLYAGAGDRKIHVWDIEAGQYLN-AMEGHKDYIHKVVMKNDAQECVS 376

Query: 382 CSMDDTVRYTNL 393
            S D TVR  ++
Sbjct: 377 ASEDGTVRMWDI 412

 Score = 30.4 bits (67), Expect = 2.1,   Method: Compositional matrix adjust.
 Identities = 16/61 (26%), Positives = 32/61 (52%)
 Frame = +2

Query: 203 RFATASADGQIFIYDGKTGEKVCALGESKAHDGGIYAISWSPDSTHLLSASGDKTSKIWD 262
           R    + D +I ++D + G+ + A+   + H   I+ +    D+   +SAS D T ++WD
Sbjct: 239 RLYAGAGDRKIHVWDIEAGQYLNAM---EGHKDYIHKVVMKNDAQECVSASEDGTVRMWD 409

Query: 263 V 263
           +
Sbjct: 410 I 412
>07665
          Length = 435

 Score = 35.4 bits (80), Expect = 0.076,   Method: Composition-based stats.
 Identities = 27/88 (30%), Positives = 44/88 (50%), Gaps = 7/88 (7%)
 Frame = -2

Query: 187 DHSRFVNCVRFSPDGNRFATASADG-QIFIYD---GKTGEKV---CALGESKAHDGGIYA 239
           +H+  +N + FSP  NR+    A G  I I+D    KT E++        SKA      +
Sbjct: 356 EHNDIINALCFSP--NRYWLCVAYGPSIKIWDLACKKTVEELRPEVVSPTSKAEQPQCLS 183

Query: 240 ISWSPDSTHLLSASGDKTSKIWDVNVNS 267
           ++WS D   L +   D T ++W V+V++
Sbjct: 182 LAWSTDGQTLFAGYSDNTIRVWQVSVSA 99
>20662
          Length = 1220

 Score = 35.0 bits (79), Expect = 0.079,   Method: Compositional matrix adjust.
 Identities = 40/174 (22%), Positives = 72/174 (41%), Gaps = 2/174 (1%)
 Frame = +2

Query: 200 DGNRFATASADGQIFIYDGKTGEKVCALGESKA-HDGGIYAISWSPDSTHLLSASGDKTS 258
           D ++       G + +++ +  +K+ ++  S   HD    ++S + D +H LSAS D   
Sbjct: 281 DSHKVLVGLDTGGVALWELQDEDKMFSMLSSACEHDDMTASVSINSDXSHYLSASYDHGI 460

Query: 259 KIWDVNVNSVVSTFPMGSNVLDQQLGCLWQKDHLLSISLSGYINYLDKNNPSKPLRVIKG 318
           K+W+ ++ S+ +       V D Q     +    LS S  G I   D    SKP   +  
Sbjct: 461 KVWNTDLTSLYTYRAHSDIVWDVQCHPT-EPALFLSCSQDGKIVLWDVRE-SKPATCLPK 634

Query: 319 HSKSIQCLTVHRNGGKSYIYS-GSHDGHINYWDSETGENDSFSGKGHTNQVSRM 371
            S   +   V        +Y+ G   GH++  D       + S + H   V+R+
Sbjct: 635 CSSGFKPTCVQWQPNARNMYAVGDEGGHVSVQDLRMVVEKNVSYQSHNRVVTRL 796
>21105
          Length = 650

 Score = 34.7 bits (78), Expect = 0.12,   Method: Compositional matrix adjust.
 Identities = 19/78 (24%), Positives = 38/78 (48%)
 Frame = +1

Query: 206 TASADGQIFIYDGKTGEKVCALGESKAHDGGIYAISWSPDSTHLLSASGDKTSKIWDVNV 265
           TA  D  I  +D  TG+ + A+    AH   + +++  P+  +LLS S D + ++W+++ 
Sbjct: 115 TAHEDRHIRFFDNNTGKLIHAM---VAHLDSVTSLAVDPNGLYLLSGSHDCSIRLWNLDS 285

Query: 266 NSVVSTFPMGSNVLDQQL 283
            + V          D+ +
Sbjct: 286 KTCVQEITSHRKKFDESI 339
>16199
          Length = 694

 Score = 34.3 bits (77), Expect = 0.13,   Method: Compositional matrix adjust.
 Identities = 20/56 (35%), Positives = 28/56 (50%)
 Frame = +2

Query: 192 VNCVRFSPDGNRFATASADGQIFIYDGKTGEKVCALGESKAHDGGIYAISWSPDST 247
           + C +F PDG  FAT + D  I I+D K    V      + H G + +IS+S   T
Sbjct: 80  LTCAQFHPDGLIFATGTEDSVIKIWDLKERANVANF---QGHQGPVTSISFSETDT 238

 Score = 30.0 bits (66), Expect = 3.1,   Method: Compositional matrix adjust.
 Identities = 14/65 (21%), Positives = 30/65 (46%)
 Frame = +2

Query: 48  PAIADIYTEHAHQVVVAKYAPSGFYIASGDISGKLRIWDTTQKEHLLKYEYQPFAGKIKD 107
           P + D        +  A++ P G   A+G     ++IWD  ++ ++    +Q   G +  
Sbjct: 41  PKVCDKSGPSVPALTCAQFHPDGLIFATGTEDSVIKIWDLKERANVAN--FQGHQGPVTS 214

Query: 108 IAWTE 112
           I+++E
Sbjct: 215 ISFSE 229
>02090
          Length = 1841

 Score = 34.3 bits (77), Expect = 0.16,   Method: Compositional matrix adjust.
 Identities = 23/87 (26%), Positives = 36/87 (41%)
 Frame = -3

Query: 177  PPFKFKFTIGDHSRFVNCVRFSPDGNRFATASADGQIFIYDGKTGEKVCALGESKAHDGG 236
            P  + K  +   +     +  SPDG    +  +DG I ++D      V    + + H  G
Sbjct: 1662 PTPRIKAELTSSAPACYALAISPDGKVCFSCCSDGNIAVWDLHNQTLV---RQFQGHTDG 1492

Query: 237  IYAISWSPDSTHLLSASGDKTSKIWDV 263
               I  SPD T L +   D T + WD+
Sbjct: 1491 ASCIDISPDGTKLWTGGLDNTVRSWDL 1411

 Score = 31.2 bits (69), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 23/98 (23%), Positives = 42/98 (42%), Gaps = 2/98 (2%)
 Frame = -3

Query: 468  NVRVYSILASTLKDEGKLLEAKGPVTDVAYSHDGAFLAVCDASKVVTVFSVADGYSENNV 527
             + ++ +   T + + +L  +      +A S DG     C +   + V+   D +++  V
Sbjct: 1689 TLSIWDLATPTPRIKAELTSSAPACYALAISPDGKVCFSCCSDGNIAVW---DLHNQTLV 1519

Query: 528  --FYGHHAKIVCLAWSPDNEHFASGGMDMMVYVWTLSD 563
              F GH     C+  SPD     +GG+D  V  W L +
Sbjct: 1518 RQFQGHTDGASCIDISPDGTKLWTGGLDNTVRSWDLRE 1405

 Score = 28.9 bits (63), Expect = 5.7,   Method: Compositional matrix adjust.
 Identities = 31/178 (17%), Positives = 68/178 (38%)
 Frame = -3

Query: 40   VILRNIDNPAIADIYTEHAHQVVVAKYAPSGFYIASGDISGKLRIWDTTQKEHLLKYEYQ 99
            + + ++ N  +   +  H         +P G  + +G +   +R WD  +   L +++  
Sbjct: 1554 IAVWDLHNQTLVRQFQGHTDGASCIDISPDGTKLWTGGLDNTVRSWDLREGRQLQQHD-- 1381

Query: 100  PFAGKIKDIAWTEDSKRIAVVGEGREKFGAVFLWDTGSSVGEITGHNKVINSVDIKQTRP 159
             F+ +I  + +    + +AV   G E      L  +     ++  H   + S+       
Sbjct: 1380 -FSSQIFSLGYCPTGEWLAV---GMESSNVEVLHHSKPDKYQLHLHESCVLSLKFAYCGK 1213

Query: 160  YRLATGSDDNCAAFFEGPPFKFKFTIGDHSRFVNCVRFSPDGNRFATASADGQIFIYD 217
            + ++TG  DN    +  P     F   + S  ++C   + D     T S D +  +Y+
Sbjct: 1212 WFVSTGK-DNLLNAWRTPYGASIFQSKESSSVLSC-DIAADDKYIVTGSGDKKATLYE 1045
>34005
          Length = 456

 Score = 33.9 bits (76), Expect = 0.18,   Method: Composition-based stats.
 Identities = 13/26 (50%), Positives = 17/26 (65%)
 Frame = +1

Query: 237 IYAISWSPDSTHLLSASGDKTSKIWD 262
           +  +SWSPD+T L S S D +  IWD
Sbjct: 121 VCGLSWSPDATFLASGSNDNSVNIWD 198
>27681
          Length = 465

 Score = 33.9 bits (76), Expect = 0.18,   Method: Composition-based stats.
 Identities = 14/36 (38%), Positives = 21/36 (58%)
 Frame = +3

Query: 237 IYAISWSPDSTHLLSASGDKTSKIWDVNVNSVVSTF 272
           I+A+ W+    ++LSA  DKT+ IWD +  S    F
Sbjct: 294 IFALKWNKRGNYILSAGVDKTTIIWDASSGSCTQQF 401

 Score = 32.7 bits (73), Expect = 0.43,   Method: Composition-based stats.
 Identities = 22/77 (28%), Positives = 34/77 (44%), Gaps = 13/77 (16%)
 Frame = +2

Query: 539 AWSPDNEHFASGGMDMMVYVWTLSD--PETKVKIQDAHRLHH----------VSSLAWLD 586
           AW+P N+  ASG  D    +W ++   P    ++   H +            V+SL W  
Sbjct: 14  AWNPTNDLLASGSGDSTARIWNMTSETPNNANQLVLRHCIQKGGTEVPSNKDVTSLDWNS 193

Query: 587 EHTLVTT-SHDASVKEW 602
           E TL+ T S+D   + W
Sbjct: 194 EGTLLATGSYDGYARLW 244

 Score = 30.4 bits (67), Expect = 1.9,   Method: Composition-based stats.
 Identities = 10/27 (37%), Positives = 19/27 (70%)
 Frame = +2

Query: 237 IYAISWSPDSTHLLSASGDKTSKIWDV 263
           ++  +W+P +  L S SGD T++IW++
Sbjct: 2   VFICAWNPTNDLLASGSGDSTARIWNM 82
>00825
          Length = 1821

 Score = 33.9 bits (76), Expect = 0.19,   Method: Compositional matrix adjust.
 Identities = 21/75 (28%), Positives = 33/75 (44%)
 Frame = -2

Query: 187  DHSRFVNCVRFSPDGNRFATASADGQIFIYDGKTGEKVCALGESKAHDGGIYAISWSPDS 246
            DH+  V  V + P G  F +A  D  I I+    G         +    G  ++ WS DS
Sbjct: 1235 DHTAAVMDVDYCPTGREFVSAGYDKVIRIFPVDKGHSREVYHTKRMQRVG--SVVWSRDS 1062

Query: 247  THLLSASGDKTSKIW 261
             ++ SAS +   ++W
Sbjct: 1061 KYIFSASDEMNIRVW 1017

 Score = 32.7 bits (73), Expect = 0.44,   Method: Compositional matrix adjust.
 Identities = 18/68 (26%), Positives = 29/68 (42%)
 Frame = -2

Query: 492  VTDVAYSHDGAFLAVCDASKVVTVFSVADGYSENNVFYGHHAKIVCLAWSPDNEHFASGG 551
            V DV Y   G         KV+ +F V  G+S          ++  + WS D+++  S  
Sbjct: 1220 VMDVDYCPTGREFVSAGYDKVIRIFPVDKGHSREVYHTKRMQRVGSVVWSRDSKYIFSAS 1041

Query: 552  MDMMVYVW 559
             +M + VW
Sbjct: 1040 DEMNIRVW 1017

 Score = 32.0 bits (71), Expect = 0.82,   Method: Compositional matrix adjust.
 Identities = 29/149 (19%), Positives = 67/149 (44%), Gaps = 4/149 (2%)
 Frame = -2

Query: 206  TASADGQIFIYDGKTGEKVCALGESKAHDGGIYAISWSPDSTHLLSASGDKTSKIWDVNV 265
            + + DG++  ++    +  C +   +AHDG ++ ++      +  S   DKT K W ++ 
Sbjct: 1820 SGACDGELICWNLPKQQMACRV---QAHDGIVHGMAAHSSGQYFFSCGSDKTIKQWSLDP 1650

Query: 266  NSVVSTFPMGS---NVLDQQLGCLWQKDHLLSISLSGYINYLDKNNPSKPLRVIKGHSKS 322
               ++  P+ +     +   L   W+ D  + ++    ++  D+   S+P+R      +S
Sbjct: 1649 EGTIAPEPVNTLLAKCIYTSLDHHWKDD--IFVTSGSRVDVWDEKR-SEPMRSFSWGVES 1479

Query: 323  IQCLTVHRNGGKSYIY-SGSHDGHINYWD 350
            +    V  N  ++Y+  + +HD  I  +D
Sbjct: 1478 VH--HVKFNPVETYLLGAAAHDRSILLYD 1398
>25526
          Length = 443

 Score = 33.9 bits (76), Expect = 0.20,   Method: Compositional matrix adjust.
 Identities = 19/64 (29%), Positives = 32/64 (50%)
 Frame = +2

Query: 181 FKFTIGDHSRFVNCVRFSPDGNRFATASADGQIFIYDGKTGEKVCALGESKAHDGGIYAI 240
           +++ IG  +  +N   FSP     A    DG + +++  T E V   G  K++ GG+  +
Sbjct: 266 YRWVIGSGA--INEFAFSPCARYLAVVGQDGFLRVFNYNTMELV---GMMKSYFGGLLCV 430

Query: 241 SWSP 244
            WSP
Sbjct: 431 CWSP 442
>03044
          Length = 1952

 Score = 33.5 bits (75), Expect = 0.24,   Method: Compositional matrix adjust.
 Identities = 20/74 (27%), Positives = 35/74 (47%), Gaps = 2/74 (2%)
 Frame = -2

Query: 190  RFVNCVRFSPDGNRFATASADGQIFIY--DGKTGEKVCALGESKAHDGGIYAISWSPDST 247
            + V C   S D N  A +  D ++ IY  +G   ++   LGE   H   +  I W+P S 
Sbjct: 1783 KAVTCHAASGDRNGLALSLNDHEVKIYKKNGSKWQETDTLGE---HGQRVTGIDWAPKSN 1613

Query: 248  HLLSASGDKTSKIW 261
             +++   D+ + +W
Sbjct: 1612 RIVTCGADRNAYVW 1571

 Score = 30.4 bits (67), Expect = 2.4,   Method: Compositional matrix adjust.
 Identities = 11/42 (26%), Positives = 19/42 (45%)
 Frame = -2

Query: 522  YSENNVFYGHHAKIVCLAWSPDNEHFASGGMDMMVYVWTLSD 563
            + E +    H  ++  + W+P +    + G D   YVWT  D
Sbjct: 1684 WQETDTLGEHGQRVTGIDWAPKSNRIVTCGADRNAYVWTYQD 1559

 Score = 29.6 bits (65), Expect = 3.6,   Method: Compositional matrix adjust.
 Identities = 18/78 (23%), Positives = 36/78 (46%), Gaps = 1/78 (1%)
 Frame = -2

Query: 133  WDTGSSVGEITGHNKVINSVDIKQTRPYRLATGSDDNCAAF-FEGPPFKFKFTIGDHSRF 191
            W    ++GE   H + +  +D        +  G+D N   + ++   ++    I   +R 
Sbjct: 1684 WQETDTLGE---HGQRVTGIDWAPKSNRIVTCGADRNAYVWTYQDGKWQPHLVILRINRA 1514

Query: 192  VNCVRFSPDGNRFATASA 209
              CV++SP+ N+FA  S+
Sbjct: 1513 ATCVKWSPEENKFAVGSS 1460
>11493
          Length = 535

 Score = 33.5 bits (75), Expect = 0.25,   Method: Compositional matrix adjust.
 Identities = 38/146 (26%), Positives = 58/146 (39%), Gaps = 8/146 (5%)
 Frame = -2

Query: 32  FLYTNGK-CVILRNIDNPAIADIYTE-----HAHQVVVAKYAPSGFYIASGDISGKLRIW 85
           ++YT GK CV + +I  P   +  ++       + +   K  P G  +  G  +  L IW
Sbjct: 435 YVYTGGKGCVKVWDISQPGNKNPVSQLDCLQRDNYIRSVKLLPDGRTLIVGGEASNLSIW 256

Query: 86  DTTQKEHLLKYEYQPFAGKIKDIAWTEDSKRIAVVGEGREKFGAVFLWDTGSS--VGEIT 143
           D       +K E    A     +A + DSK    V       G + +WD  +   V +  
Sbjct: 255 DLASPTPRIKAELTSAAPACYALAISPDSK----VCFSCCSDGNIAVWDLHNEILVRQFQ 88

Query: 144 GHNKVINSVDIKQTRPYRLATGSDDN 169
           GH    + +DI      RL TG  DN
Sbjct: 87  GHTDGASCIDISPDG-SRLWTGGLDN 13

 Score = 30.4 bits (67), Expect = 2.2,   Method: Compositional matrix adjust.
 Identities = 21/83 (25%), Positives = 34/83 (40%), Gaps = 1/83 (1%)
 Frame = -2

Query: 191 FVNCVRFSPDGNRFATASADGQIFIYD-GKTGEKVCALGESKAHDGGIYAISWSPDSTHL 249
           ++  V+  PDG           + I+D      ++ A   S A     YA++ SPDS   
Sbjct: 333 YIRSVKLLPDGRTLIVGGEASNLSIWDLASPTPRIKAELTSAAP--ACYALAISPDSKVC 160

Query: 250 LSASGDKTSKIWDVNVNSVVSTF 272
            S   D    +WD++   +V  F
Sbjct: 159 FSCCSDGNIAVWDLHNEILVRQF 91
>12960
          Length = 550

 Score = 33.5 bits (75), Expect = 0.28,   Method: Compositional matrix adjust.
 Identities = 20/75 (26%), Positives = 33/75 (44%), Gaps = 3/75 (4%)
 Frame = +2

Query: 21  KILGGDPKGDHFLYTNG---KCVILRNIDNPAIADIYTEHAHQVVVAKYAPSGFYIASGD 77
           ++L     GD+    +G   K V+L ++ +      Y +HA  V   K+      I SG 
Sbjct: 305 EVLDAQGSGDNSQICSGGIDKTVVLFDVASGQALRKYRDHAGTVNCVKFNEESTVILSGS 484

Query: 78  ISGKLRIWDTTQKEH 92
           +   +R WDT  + H
Sbjct: 485 LDNTVRAWDTRSRSH 529

 Score = 29.6 bits (65), Expect = 4.1,   Method: Compositional matrix adjust.
 Identities = 27/114 (23%), Positives = 54/114 (47%), Gaps = 3/114 (2%)
 Frame = +2

Query: 492 VTDVAYSHDGAFLAVCDASKVVTVFSVADGYSEN--NVFYGHHAKIVCLAWSPDNEHFAS 549
           V  V +S D  +   C + K V ++   + + E     + GH  +++    S DN    S
Sbjct: 182 VRAVRFSVDSRYCMTCGSDKSVKLW---NPHRELFLKTYIGHGHEVLDAQGSGDNSQICS 352

Query: 550 GGMDMMVYVWTLSDPETKVKIQDAHRLHHVSSLAWLDEHTLVTT-SHDASVKEW 602
           GG+D  V ++ ++  +   K +D      V+ + + +E T++ + S D +V+ W
Sbjct: 353 GGIDKTVVLFDVASGQALRKYRD--HAGTVNCVKFNEESTVILSGSLDNTVRAW 508
>14500
          Length = 1238

 Score = 33.1 bits (74), Expect = 0.30,   Method: Compositional matrix adjust.
 Identities = 17/61 (27%), Positives = 27/61 (44%)
 Frame = +2

Query: 214 FIYDGKTGEKVCALGESKAHDGGIYAISWSPDSTHLLSASGDKTSKIWDVNVNSVVSTFP 273
           F+Y G+  +    +G    H   +  + WSPD  +L S + D    +W   V    ST P
Sbjct: 5   FLYYGRVADH--HVGTLSGHSQEVCGLRWSPDGKYLASGANDNLLCVWPAQVTGGNSTQP 178

Query: 274 M 274
           +
Sbjct: 179 L 181

 Score = 32.7 bits (73), Expect = 0.40,   Method: Compositional matrix adjust.
 Identities = 13/30 (43%), Positives = 19/30 (63%)
 Frame = +2

Query: 530 GHHAKIVCLAWSPDNEHFASGGMDMMVYVW 559
           GH  ++  L WSPD ++ ASG  D ++ VW
Sbjct: 53  GHSQEVCGLRWSPDGKYLASGANDNLLCVW 142
>25400
          Length = 462

 Score = 33.1 bits (74), Expect = 0.32,   Method: Compositional matrix adjust.
 Identities = 21/57 (36%), Positives = 27/57 (47%)
 Frame = +3

Query: 206 TASADGQIFIYDGKTGEKVCALGESKAHDGGIYAISWSPDSTHLLSASGDKTSKIWD 262
           +  A G I IYD  TG  V  L     H   +  +SW P +  L+S+S D T   WD
Sbjct: 12  SGCATGTILIYDLLTGRVVRKL--DGGHRSCVRDVSWHPYTNTLISSSWDGTVGKWD 176
>03156
          Length = 1014

 Score = 33.1 bits (74), Expect = 0.33,   Method: Compositional matrix adjust.
 Identities = 24/92 (26%), Positives = 41/92 (44%)
 Frame = +1

Query: 188 HSRFVNCVRFSPDGNRFATASADGQIFIYDGKTGEKVCALGESKAHDGGIYAISWSPDST 247
           H R +  V +    N   +AS D  I ++         ++ +   HD  + AI  + D+T
Sbjct: 52  HDREITKVCYGASCNGMFSASRDKTIKMWQRGNSH---SIRDFIGHDMVVTAIHLNTDNT 222

Query: 248 HLLSASGDKTSKIWDVNVNSVVSTFPMGSNVL 279
            L S S D T +IWDV   + +    +  N++
Sbjct: 223 LLCSGSRDNTVRIWDVETGACLRQNNIPQNLV 318

 Score = 30.4 bits (67), Expect = 2.3,   Method: Compositional matrix adjust.
 Identities = 30/113 (26%), Positives = 50/113 (44%), Gaps = 4/113 (3%)
 Frame = +1

Query: 492 VTDVAY--SHDGAFLAVCDASKVVTVFSVADGYSENNVFYGHHAKIVCLAWSPDNEHFAS 549
           +T V Y  S +G F A  D  K + ++   + +S  + F GH   +  +  + DN    S
Sbjct: 64  ITKVCYGASCNGMFSASRD--KTIKMWQRGNSHSIRD-FIGHDMVVTAIHLNTDNTLLCS 234

Query: 550 GGMDMMVYVWTLSDPETKVKI-QDAHRLHHVSSLAWL-DEHTLVTTSHDASVK 600
           G  D  V +W   D ET   + Q+    + V+ + WL   H ++    D  V+
Sbjct: 235 GSRDNTVRIW---DVETGACLRQNNIPQNLVTDVKWLPGSHLIIQAGEDKEVR 384

 Score = 29.3 bits (64), Expect = 4.4,   Method: Compositional matrix adjust.
 Identities = 19/63 (30%), Positives = 27/63 (42%)
 Frame = +1

Query: 292 LLSISLSGYINYLDKNNPSKPLRVIKGHSKSIQCLTVHRNGGKSYIYSGSHDGHINYWDS 351
           + S S    I    + N S  +R   GH   +    +H N   + + SGS D  +  WD 
Sbjct: 100 MFSASRDKTIKMWQRGN-SHSIRDFIGHDMVVT--AIHLNTDNTLLCSGSRDNTVRIWDV 270

Query: 352 ETG 354
           ETG
Sbjct: 271 ETG 279
>16105
          Length = 960

 Score = 33.1 bits (74), Expect = 0.37,   Method: Compositional matrix adjust.
 Identities = 28/124 (22%), Positives = 46/124 (37%), Gaps = 1/124 (0%)
 Frame = -2

Query: 233 HDGGIYAISWSPDSTHLL-SASGDKTSKIWDVNVNSVVSTFPMGSNVLDQQLGCLWQKDH 291
           H G +  I W P + +++ SAS D T K+W +  + +V+                     
Sbjct: 578 HKGAVLDIQWCPHNDNVIASASDDCTVKVWQIPDSGLVT--------------------- 462

Query: 292 LLSISLSGYINYLDKNNPSKPLRVIKGHSKSIQCLTVHRNGGKSYIYSGSHDGHINYWDS 351
                           N + P+  + GH K   CL V     ++ + S   D  I +W+ 
Sbjct: 461 ----------------NLTDPVVDLVGHQKRC-CLIVWHPSAQNVLVSAGADNKILFWNV 333

Query: 352 ETGE 355
            TGE
Sbjct: 332 GTGE 321
>19140
          Length = 573

 Score = 32.3 bits (72), Expect = 0.56,   Method: Compositional matrix adjust.
 Identities = 17/53 (32%), Positives = 26/53 (49%), Gaps = 1/53 (1%)
 Frame = -3

Query: 221 GEKVC-ALGESKAHDGGIYAISWSPDSTHLLSASGDKTSKIWDVNVNSVVSTF 272
           G + C  L + K H   + A+  + D T  LS S D T ++W +     V+TF
Sbjct: 529 GPRTCHKLMKLKGHTDNVKALVLNRDGTQCLSGSSDGTIRLWSLGQQRCVATF 371
>10264
          Length = 416

 Score = 32.3 bits (72), Expect = 0.57,   Method: Composition-based stats.
 Identities = 18/77 (23%), Positives = 33/77 (42%), Gaps = 1/77 (1%)
 Frame = -1

Query: 530 GHHAKIVCLAWSPDNE-HFASGGMDMMVYVWTLSDPETKVKIQDAHRLHHVSSLAWLDEH 588
           GH  ++  ++WSP ++    S G D   +VW +       + +           + LD  
Sbjct: 251 GHSQRVTDMSWSPHHDARLVSVGYDAEAFVWDVQKGTALAQFKGHMGRLLTCQFSGLDPD 72

Query: 589 TLVTTSHDASVKEWTIT 605
            ++T   DASV  W ++
Sbjct: 71  LVMTGGSDASVHVWRVS 21
>36111
          Length = 687

 Score = 32.3 bits (72), Expect = 0.57,   Method: Compositional matrix adjust.
 Identities = 39/141 (27%), Positives = 52/141 (36%), Gaps = 27/141 (19%)
 Frame = +2

Query: 128 GAVFLWDTGSSVGEITGHNKVINSVDIKQTRPYRLATGSDDNCAAFFEGPP--------- 178
           G    W T SS G  T   K   S       P R AT     C+A  +G           
Sbjct: 17  GTCATWATSSSDGNPTSSIKHAASA----ASPTRWAT-----CSALSKGASP*NI*TLAQ 169

Query: 179 -FKFKFTIGDHS---------RFVNCVRFSPDGNRFATASADGQIFIYDGKTGEKVCALG 228
            FK K+    H            VN V F    N FAT  +DG + I+DG   +++C   
Sbjct: 170 TFKTKYAFKCHRIKEDSLEKIYPVNAVAFHNVYNTFATGGSDGYVNIWDGFHKKRLCXFH 349

Query: 229 E--------SKAHDGGIYAIS 241
                    + +HDG + AI+
Sbjct: 350 RYPTSIASLAFSHDGNVLAIA 412
>35844
          Length = 668

 Score = 31.6 bits (70), Expect = 0.99,   Method: Compositional matrix adjust.
 Identities = 12/33 (36%), Positives = 21/33 (63%)
 Frame = +3

Query: 570 IQDAHRLHHVSSLAWLDEHTLVTTSHDASVKEW 602
           I++AH    ++ L WLD +T+++T  D + K W
Sbjct: 15  IKNAHPQSQITRLVWLDNNTVISTGQDCNTKVW 113
>04524
          Length = 1340

 Score = 31.6 bits (70), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 25/101 (24%), Positives = 40/101 (39%), Gaps = 10/101 (9%)
 Frame = -1

Query: 471  VYSILAST---LKDEGK-------LLEAKGPVTDVAYSHDGAFLAVCDASKVVTVFSVAD 520
            VY+   +T   +KDEG+       LL     V DV  +     +  CD  + + V    +
Sbjct: 1112 VYTFPTTTQVEVKDEGEVKTHGQLLLGHLSMVLDVCLTGREGHVVTCDRDEKIRVSQFPN 933

Query: 521  GYSENNVFYGHHAKIVCLAWSPDNEHFASGGMDMMVYVWTL 561
             Y+ +    GH   + CL +  +     SG  D  V  W +
Sbjct: 932  AYNIHTYCLGHTQFVNCLVYVEEFRVLISGSGDCTVRAWNM 810
>31118
          Length = 390

 Score = 31.2 bits (69), Expect = 1.1,   Method: Composition-based stats.
 Identities = 19/59 (32%), Positives = 26/59 (44%), Gaps = 2/59 (3%)
 Frame = -2

Query: 188 HSRFVNCVRFSPDGNRFATASADGQIFIYD--GKTGEKVCALGESKAHDGGIYAISWSP 244
           HS  + C+RFSP      T S D  I + D  G     + ++  +K  D  I  I W P
Sbjct: 383 HSAEIRCIRFSPSAYYMLTCSYDSTIKLTDLQGDLANDIASVVVAKHKDKAI-TIRWHP 210
>10162
          Length = 1629

 Score = 31.2 bits (69), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 52/237 (21%), Positives = 90/237 (37%), Gaps = 9/237 (3%)
 Frame = +3

Query: 53  IYTEHAHQVVVAKYAPSGFYIASGDISGKLRIWD--TTQKEHLLKYEYQPFAGKIKDIAW 110
           +   H    +  K  P+G Y+  G   G +++WD  T    H  ++   P   ++ +   
Sbjct: 144 MLQSHGQPSLCGKILPNGKYVCVGYSDGVVKLWDLKTGTAVHTWQHSVMP-EEEMPERNS 320

Query: 111 TEDSKRIAVVGEGREKFGAVFLWDTGSSVGEITGHNKVINSVDIKQT-RPYRLATG---S 166
           +++     V  E  E   A+   D        +  N +I S     T + + +++G   S
Sbjct: 321 SDEEDGEEVEVEREEDTVAILCVD-------CSADNALIMSGCADATAKVFNVSSGKLXS 479

Query: 167 DDNCAAFFEGPPFKFKFTIGDHSRFVNCVRFSPDGNRFATASADGQIFIYDGKTGEKVCA 226
             NCAA  +           D    V  V F P     ATA+  G + ++D  T      
Sbjct: 480 AFNCAASQDSQ---------DKDNSVESVAFCPVSPYAATATNSGSVQVWDLPTS----V 620

Query: 227 LGESKAHDGGIYAISWSPDSTHLLSASGDKTSKIWDVN---VNSVVSTFPMGSNVLD 280
              S  H  G+  + WS  +  L +A  D   ++WD       +V++     S +LD
Sbjct: 621 ARHSFQHPEGVCKLQWSSSTALLYTACLDGVMRVWDARSGASKAVLTGHARNSCILD 791
>12409
          Length = 674

 Score = 31.2 bits (69), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 24/86 (27%), Positives = 39/86 (45%), Gaps = 2/86 (2%)
 Frame = -1

Query: 52  DIYTEHAHQVVVAKYAPSGFYIASGDISGKLRIWDTTQKEHLLK--YEYQPFAGKIKDIA 109
           D Y EH   V  ++++ SG +IAS D  G ++IW  + +           PF      + 
Sbjct: 353 DEYLEHQSAVCYSRFSLSGQHIASLDADGIVKIWTWSPQPCTAATVMSRAPFLS----LD 186

Query: 110 WTEDSKRIAVVGEGREKFGAVFLWDT 135
           W   S R  ++G    + G + L+DT
Sbjct: 185 WASKSDRWLLLG---NQSGQIRLFDT 117
>11915
          Length = 737

 Score = 31.2 bits (69), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 22/88 (25%), Positives = 39/88 (44%), Gaps = 1/88 (1%)
 Frame = +1

Query: 204 FATASADGQIFIYDGKTGEKVCALGESKAHDGGIYAISWSPD-STHLLSASGDKTSKIWD 262
            AT    G+I +++ +TG+    L E   H   ++ + ++ D S  L+SAS D T K+W+
Sbjct: 451 LATGHVSGRIKLWNCETGK---LLIEMMDHKATVHDLHFAADNSLCLMSASHDGTVKLWE 621

Query: 263 VNVNSVVSTFPMGSNVLDQQLGCLWQKD 290
            +     + +            C W  D
Sbjct: 622 FDDQGDCNMYLTLRTNAKHAFSCRWSHD 705
>13486
          Length = 1509

 Score = 30.8 bits (68), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 14/33 (42%), Positives = 20/33 (60%)
 Frame = -1

Query: 484 KLLEAKGPVTDVAYSHDGAFLAVCDASKVVTVF 516
           KLL    PV DV ++ D + LA CDA  +V ++
Sbjct: 915 KLLGHSAPVLDVCFNCDESLLASCDAQGMVIIW 817
>04358
          Length = 2430

 Score = 30.8 bits (68), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 19/76 (25%), Positives = 35/76 (46%), Gaps = 2/76 (2%)
 Frame = +1

Query: 487  EAKGPVTDVAYSHDGAF--LAVCDASKVVTVFSVADGYSENNVFYGHHAKIVCLAWSPDN 544
            ++  P   VA +H G    L + D  +V  V S++ G+++          + CL W    
Sbjct: 2032 QSTSPPCLVAGTHTGDLHVLDLSDLEEVKVVRSLSGGHTDT---------VRCLHWDKQT 2184

Query: 545  EHFASGGMDMMVYVWT 560
            +   +GG D M+ +W+
Sbjct: 2185 QTLVTGGEDSMLCLWS 2232
>17602
          Length = 481

 Score = 30.8 bits (68), Expect = 1.8,   Method: Compositional matrix adjust.
 Identities = 14/61 (22%), Positives = 28/61 (45%)
 Frame = +3

Query: 36  NGKCVILRNIDNPAIADIYTEHAHQVVVAKYAPSGFYIASGDISGKLRIWDTTQKEHLLK 95
           +G C I        +  +  +    V   K++P+G YI +  +   L++WD ++ + L  
Sbjct: 117 DGLCRIWDTASGQCLXTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKT 296

Query: 96  Y 96
           Y
Sbjct: 297 Y 299

 Score = 30.4 bits (67), Expect = 2.1,   Method: Compositional matrix adjust.
 Identities = 15/45 (33%), Positives = 25/45 (55%)
 Frame = +3

Query: 311 KPLRVIKGHSKSIQCLTVHRNGGKSYIYSGSHDGHINYWDSETGE 355
           K L+ +  HS  +  +  +R+G  S I S S+DG    WD+ +G+
Sbjct: 27  KCLKTLPAHSDPVTAVHFNRDG--SLIVSSSYDGLCRIWDTASGQ 155

 Score = 30.4 bits (67), Expect = 2.3,   Method: Compositional matrix adjust.
 Identities = 22/95 (23%), Positives = 39/95 (41%), Gaps = 3/95 (3%)
 Frame = +3

Query: 491 PVTDVAYSHDGAFLAVCDASKVVTVFSVADGYSENNVFYGHHAKIVCLAWS---PDNEHF 547
           PV+ V +S +G ++        + ++  + G      + GH  +  C+  +      +  
Sbjct: 189 PVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLK-TYVGHRNEKYCIFANFSVTGGKWI 365

Query: 548 ASGGMDMMVYVWTLSDPETKVKIQDAHRLHHVSSL 582
            SG  D MVY+W L D     +   +HR   V  L
Sbjct: 366 VSGSEDNMVYIWNLLDQGDSTEATGSHRRGAVLCL 470
>17298
          Length = 476

 Score = 26.2 bits (56), Expect(2) = 1.9,   Method: Compositional matrix adjust.
 Identities = 10/34 (29%), Positives = 19/34 (55%)
 Frame = -1

Query: 187 DHSRFVNCVRFSPDGNRFATASADGQIFIYDGKT 220
           DH+  VNCV+F+ +     + S D  +  +D ++
Sbjct: 218 DHAGTVNCVKFNEESTVILSGSLDNTVRAWDTRS 117

 Score = 22.7 bits (47), Expect(2) = 1.9,   Method: Composition-based stats.
 Identities = 14/43 (32%), Positives = 20/43 (46%)
 Frame = -2

Query: 130 VFLWDTGSSVGEITGHNKVINSVDIKQTRPYRLATGSDDNCAA 172
           + L D+ SS   +  HN + +S      R  +L  GSDD  A 
Sbjct: 412 ILLPDSFSSFSLVHSHNSLGSSSIWLSARLRQLRCGSDDRSAG 284

 Score = 30.4 bits (67), Expect = 2.3,   Method: Compositional matrix adjust.
 Identities = 13/39 (33%), Positives = 18/39 (46%)
 Frame = -1

Query: 54  YTEHAHQVVVAKYAPSGFYIASGDISGKLRIWDTTQKEH 92
           Y +HA  V   K+      I SG +   +R WDT  + H
Sbjct: 224 YRDHAGTVNCVKFNEESTVILSGSLDNTVRAWDTRSRSH 108
>15118
          Length = 1074

 Score = 30.4 bits (67), Expect = 1.9,   Method: Compositional matrix adjust.
 Identities = 23/78 (29%), Positives = 32/78 (41%)
 Frame = +3

Query: 484 KLLEAKGPVTDVAYSHDGAFLAVCDASKVVTVFSVADGYSENNVFYGHHAKIVCLAWSPD 543
           K L+    ++ +    D   LAV      V+V  V D      VF GH   I  L++S D
Sbjct: 312 KELKMSEGISRILLHRDSNMLAVVLEDFTVSVIDV-DTLRVVRVFSGHSNSITDLSFSGD 488

Query: 544 NEHFASGGMDMMVYVWTL 561
                +  MD  V  W+L
Sbjct: 489 GRWLITASMDCTVRTWSL 542
>13890
          Length = 630

 Score = 30.4 bits (67), Expect = 2.2,   Method: Compositional matrix adjust.
 Identities = 33/176 (18%), Positives = 73/176 (41%), Gaps = 13/176 (7%)
 Frame = +1

Query: 65  KYAPSGFYIASGDISGKLRIWDTTQKE---HLLKYEYQPFAGKIKDIAWTEDSKRIAVVG 121
           ++ P   ++ +   +  +++WD    E    +L ++ Q   G+++D+ ++ D + +   G
Sbjct: 1   RFHPVTPHLVATGTTDCIQVWDVRHPEVPVRVLTHKEQ--LGQVQDVMFSHDGQEVFSCG 174

Query: 122 E--GREKFG-AVFLWDTGSSV---GEITGHNKVINSVDIKQTRPYRLATGSDDNCAAFFE 175
           +   RE    ++  WD  + V    +I      +  + +   +   LA       A F  
Sbjct: 175 DVVSRESSDRSIMAWDFRTGVILSNQIFQERYTVTRLMLHPYQSQFLAQTQAGYIAVFST 354

Query: 176 GPPFKF----KFTIGDHSRFVNCVRFSPDGNRFATASADGQIFIYDGKTGEKVCAL 227
             P+K     +F     + +      S DG+   + S+DG++  Y   T +K+  L
Sbjct: 355 QRPYKMNKNKRFEGHKTAGYNIGASLSQDGSIVYSGSSDGKLHCYSFNTTKKIRTL 522
>27475
          Length = 369

 Score = 30.4 bits (67), Expect = 2.4,   Method: Compositional matrix adjust.
 Identities = 19/46 (41%), Positives = 23/46 (50%), Gaps = 2/46 (4%)
 Frame = +2

Query: 221 GEKV-CALGESKAHDGGIYAISWSPDSTHL-LSASGDKTSKIWDVN 264
           GE V CA     +H G +  + WSP   HL LS S D   K+WD  
Sbjct: 35  GETVKCAF---TSHTGWVTGVDWSPTREHLFLSGSYDNVLKLWDTR 163

 Score = 29.3 bits (64), Expect = 5.5,   Method: Compositional matrix adjust.
 Identities = 15/58 (25%), Positives = 25/58 (43%), Gaps = 1/58 (1%)
 Frame = +2

Query: 519 ADGYSENNVFYGHHAKIVCLAWSPDNEH-FASGGMDMMVYVWTLSDPETKVKIQDAHR 575
            +G +    F  H   +  + WSP  EH F SG  D ++ +W    P+  +   + H 
Sbjct: 29  TEGETVKCAFTSHTGWVTGVDWSPTREHLFLSGSYDNVLKLWDTRSPKATLYDMNWHE 202
>21921
          Length = 1341

 Score = 30.0 bits (66), Expect = 2.8,   Method: Compositional matrix adjust.
 Identities = 27/118 (22%), Positives = 47/118 (39%), Gaps = 5/118 (4%)
 Frame = -1

Query: 285 CLWQKDHLLSISLSGYINYLDKNNPSKPLR-----VIKGHSKSIQCLTVHRNGGKSYIYS 339
           C  Q+   +++     +  L K    +P       V KGH+  ++ +     G   ++ S
Sbjct: 603 CARQRKMKMNVDPQDLLPKLPKPKDLRPFPTTQALVYKGHTGIVRSICPDPTG--QWLVS 430

Query: 340 GSHDGHINYWDSETGENDSFSGKGHTNQVSRMTVNESEQLVSCSMDDTVRYTNLTLRD 397
           GS DG I +W+  +G        G          N S  +V+ +++ TV   N  L D
Sbjct: 429 GSDDGTIRFWEVSSGRCMKTLQVGGCVTSVAWNPNPSLCVVAATLNTTVLLINPGLGD 256
>07542
          Length = 1027

 Score = 30.0 bits (66), Expect = 3.1,   Method: Compositional matrix adjust.
 Identities = 15/50 (30%), Positives = 26/50 (52%)
 Frame = +1

Query: 301 INYLDKNNPSKPLRVIKGHSKSIQCLTVHRNGGKSYIYSGSHDGHINYWD 350
           IN  D  NP K L V+  H  + Q +    +    ++ SG+H+G++  +D
Sbjct: 145 INCFDIRNPEKILYVLYRHVATNQRMYFDIDRSSQFLLSGNHNGNVTTFD 294
>18981
          Length = 407

 Score = 30.0 bits (66), Expect = 3.1,   Method: Composition-based stats.
 Identities = 31/116 (26%), Positives = 58/116 (50%), Gaps = 5/116 (4%)
 Frame = -2

Query: 245 DSTHLL-----SASGDKTSKIWDVNVNSVVSTFPMGSNVLDQQLGCLWQKDHLLSISLSG 299
           D  HLL     SA+ D+T ++W +    ++ T   G N  D +  C++ +  ++S S   
Sbjct: 406 DHIHLLDNMIISAATDRTLRVWCLKNTCLLHTL-RGHND-DVECVCIYGR-RVVSGSWDK 236

Query: 300 YINYLDKNNPSKPLRVIKGHSKSIQCLTVHRNGGKSYIYSGSHDGHINYWDSETGE 355
            +   + +   +P+  + GH+++I    V  + GK+   SGS DG +  W  +TG+
Sbjct: 235 TLIVWEVDT-GRPVHQLHGHTEAIT--AVQFDEGKAV--SGSADGDVRTWALDTGQ 83
>38362
          Length = 1255

 Score = 30.0 bits (66), Expect = 3.1,   Method: Compositional matrix adjust.
 Identities = 31/133 (23%), Positives = 56/133 (42%), Gaps = 24/133 (18%)
 Frame = -1

Query: 156 QTRPYRLATGSDDNCAA------FFEGPPFKFKF----TIGDHSRFVNCVRFSPDGNR-- 203
           +  P  +ATGSDD+  +       +E      K+    ++G  +  V+ + F+P+  R  
Sbjct: 922 RVHPPMIATGSDDSNPSSGAKVGIYEYSDVNRKWNKVESLGTVTDPVHDIYFAPNVGRSY 743

Query: 204 --FATASADGQIFIYDGKTGE----------KVCALGESKAHDGGIYAISWSPDSTHLLS 251
              A AS +  I        E          ++  +G   +HD  ++ +SW+   T L+S
Sbjct: 742 HLLAIASKELSIVSLKPLRKEPSSGSSSSKFEIRQVGLFDSHDSQVWRVSWNVTGTILVS 563

Query: 252 ASGDKTSKIWDVN 264
           +  D   +IW  N
Sbjct: 562 SGADGCVRIWKAN 524
>31864
          Length = 545

 Score = 29.6 bits (65), Expect = 3.7,   Method: Compositional matrix adjust.
 Identities = 14/29 (48%), Positives = 17/29 (58%)
 Frame = +2

Query: 530 GHHAKIVCLAWSPDNEHFASGGMDMMVYV 558
           GH   I  LA+ PD + +ASGG D  V V
Sbjct: 335 GHFGPINSLAFHPDGKSYASGGEDGFVRV 421
>21960
          Length = 756

 Score = 29.3 bits (64), Expect = 4.5,   Method: Compositional matrix adjust.
 Identities = 19/50 (38%), Positives = 25/50 (50%), Gaps = 2/50 (4%)
 Frame = +1

Query: 526 NVFYGHHAKIV-CLAWSPDNEHFASGGMDMMVYVWTLS-DPETKVKIQDA 573
           N   G  A +V CL   P     A+ G+D  V +WT S  PET+V   +A
Sbjct: 472 NFMKGDDAGVVNCLEQHPTMPVLATSGLDHNVKIWTPSAKPETEVPCSEA 621
>37142
          Length = 327

 Score = 29.3 bits (64), Expect = 4.6,   Method: Compositional matrix adjust.
 Identities = 14/80 (17%), Positives = 36/80 (45%), Gaps = 1/80 (1%)
 Frame = +2

Query: 183 FTIGDHSRFVNCVRFSP-DGNRFATASADGQIFIYDGKTGEKVCALGESKAHDGGIYAIS 241
             +  H+  V  + F+P   N  A+ +++ +I+I+D    +     G+       +  ++
Sbjct: 86  LQLTKHTGAVKALDFNPFQTNLLASGASESEIYIWDLNKPDNPMTPGQKSQPPEEVSCVA 265

Query: 242 WSPDSTHLLSASGDKTSKIW 261
           W+    H+L+++      +W
Sbjct: 266 WNRQVQHILASNFAARCVVW 325
>14105
          Length = 429

 Score = 28.9 bits (63), Expect = 6.6,   Method: Compositional matrix adjust.
 Identities = 18/61 (29%), Positives = 30/61 (49%), Gaps = 3/61 (4%)
 Frame = +3

Query: 51  ADIYTEHAHQVVVAKYAPSGFYIASGDISGKLRIWDTTQKEHL---LKYEYQPFAGKIKD 107
           A I  + A  +    + PSG ++  GD SGKL ++D    EHL    + E+  F   + +
Sbjct: 168 ASIVVDGAPALNRVSWTPSGLHVTIGDESGKLYVYDVA--EHLALPTRDEWSRFNATLNE 341

Query: 108 I 108
           +
Sbjct: 342 L 344
>27270
          Length = 1078

 Score = 28.9 bits (63), Expect = 7.1,   Method: Compositional matrix adjust.
 Identities = 26/107 (24%), Positives = 42/107 (39%), Gaps = 1/107 (0%)
 Frame = +2

Query: 500 DGAFLAVCDASKVVTVFSVADGYSENNVFYGHHAKIVCLAWSPDNEHFASGGMDMMVYVW 559
           D A +AV  A   V ++SV      + +  GH   +  + W  D     S  +D  V  W
Sbjct: 176 DSAVVAVGSADGSVGLYSVETHTYTHMLNKGHSKAVTDMCWRADGRTLYSSSLDGHVIGW 355

Query: 560 TLSDPETKVKIQDAHRLHH-VSSLAWLDEHTLVTTSHDASVKEWTIT 605
            ++      K +     HH V  +       L+T  H  ++K W +T
Sbjct: 356 NVNTLHMIEKWKATSGRHHGVHCVCLCSSSRLLTADH--TIKMWDLT 490

 Score = 28.5 bits (62), Expect = 8.8,   Method: Compositional matrix adjust.
 Identities = 49/203 (24%), Positives = 77/203 (37%), Gaps = 18/203 (8%)
 Frame = +2

Query: 198 SPDGNRFATASADGQIFIYDGKTGEKVCALGESKAHDGGIYAISWSPDSTHLLSASGDKT 257
           + D    A  SADG + +Y  +T      L  +K H   +  + W  D   L S+S D  
Sbjct: 170 AADSAVVAVGSADGSVGLYSVETHTYTHML--NKGHSKAVTDMCWRADGRTLYSSSLDGH 343

Query: 258 SKIWDVNVNSVVSTFPMGSNVLDQ-QLGCLWQKDHLLSISLSGYINYLDKNNPSKPLRVI 316
              W+VN   ++  +   S         CL     LL+   +  +  L   N    L+  
Sbjct: 344 VIGWNVNTLHMIEKWKATSGRHHGVHCVCLCSSSRLLTADHTIKMWDLTTKN---VLQEF 514

Query: 317 KGHSKS-IQCLTVHRNGGKS----------YIYS-GSHDGHINYW--DSETGEN---DSF 359
            GHS   I+ L V +   +           Y++S  + D  IN W  DSE+ +     SF
Sbjct: 515 SGHSTEVIKLLPVLKPSSEQNDIGDSNLACYVFSAAAADRTINVWRCDSESSQATAVTSF 694

Query: 360 SGKGHTNQVSRMTVNESEQLVSC 382
                 + +S M   ++E    C
Sbjct: 695 ELTDEPSDLSIMLCKKTESQAGC 763
>25880
          Length = 423

 Score = 28.5 bits (62), Expect = 8.3,   Method: Compositional matrix adjust.
 Identities = 19/55 (34%), Positives = 27/55 (49%), Gaps = 1/55 (1%)
 Frame = +2

Query: 35  TNGKCVILRNIDNP-AIADIYTEHAHQVVVAKYAPSGFYIASGDISGKLRIWDTT 88
           +N K V + N++ P A  ++Y  H   +  A YA       SG   G LR+W TT
Sbjct: 113 SNEKLVRVFNLEQPDAEPELYGGHTGAIKRALYA-------SGSEDGTLRLWQTT 256
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|21624617|ref|NP_081018.1| RIKEN cDNA 1110007M04 [Mus
musculus]
         (173 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

00453                                                                  50   8e-12
09866                                                                  27   3.8  
>00453
          Length = 2955

 Score = 49.7 bits (117), Expect(2) = 8e-12,   Method: Compositional matrix adjust.
 Identities = 31/107 (28%), Positives = 58/107 (54%), Gaps = 1/107 (0%)
 Frame = -1

Query: 56  KKDNKLLSLLRDVYVDSKDPVPALPVKVEPRQEPKEFR-LPIGNHFDKNITDIPKGKITV 114
           KK  KL   L+ V V+S    P + +K   R  P++ R +    +    + ++P+G++ +
Sbjct: 324 KKHEKLDEYLKKVRVESVGDNPEIQLKKSTRALPEDRRKVTQAEYGFPEVENVPEGRVNL 145

Query: 115 VEALTLLNNHKLSPETWTAEKIAQEYYLELKDVNSLLKYFVTFEVKI 161
            + L  ++ H+L+P   + EKIA++Y L+   V  ++KYF T  + I
Sbjct: 144 RQVLEFISLHRLNPRENSVEKIARDYKLDATQVQHVVKYFQTLNMHI 4

 Score = 36.2 bits (82), Expect(2) = 8e-12,   Method: Compositional matrix adjust.
 Identities = 17/42 (40%), Positives = 25/42 (59%)
 Frame = -2

Query: 9   LRNFNVEKRAEREISKRKPSMAPKHPSTRDLLQEHRSQYPEI 50
           L+NFNVE RA R +   +   AP+HPST   +++     PE+
Sbjct: 464 LKNFNVENRAHRALESEQLRSAPRHPSTATAIEKILQDNPEV 339
>09866
          Length = 968

 Score = 26.9 bits (58), Expect = 3.8,   Method: Compositional matrix adjust.
 Identities = 24/82 (29%), Positives = 38/82 (46%), Gaps = 9/82 (10%)
 Frame = -3

Query: 99  HFDKN----ITDIP-----KGKITVVEALTLLNNHKLSPETWTAEKIAQEYYLELKDVNS 149
           HF  N    IT+I      +GK T     TL  N  +   TW   KI  + ++ ++    
Sbjct: 648 HFHLNNTTQITEINLKLK*RGKSTQGNE*TLSENLXIKGTTWLC*KILLQCHINIRYYKD 469

Query: 150 LLKYFVTFEVKILPPEDRKAIQ 171
           LLK + T  +K++  +DR  +Q
Sbjct: 468 LLKCWRTL-MKVVFRQDRTKMQ 406
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31982724|ref|NP_058056.2| MYB binding protein (P160)
1a [Mus musculus]
         (1344 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

01783                                                                  69   9e-12
24326                                                                  30   6.6  
13662                                                                  30   8.3  
>01783
          Length = 2800

 Score = 69.3 bits (168), Expect = 9e-12,   Method: Compositional matrix adjust.
 Identities = 36/100 (36%), Positives = 56/100 (56%)
 Frame = +2

Query: 592  AFQHLLLLVGLHIFKSPAESCDVLGDIQTCIKKSMEQNPRRSRSRAKASQEPVWVEVMVE 651
            AF  L+L +   +F  P  + ++L DI  C  K+     ++  ++     EP WVEV+ E
Sbjct: 959  AFTLLILHLAFDLFTEPESTVELLQDIYVCRDKA----AKKHSAKHAGHGEPHWVEVITE 1126

Query: 652  ILLSLLAQPSNLMRQVVRSVFGHICPHLTPRCLQLILAVL 691
            ILLS+L++ S L R+   +VF  +  HLTP  LQL+  V+
Sbjct: 1127 ILLSMLSRASKLARKTTVTVFRSLSAHLTPTALQLVTQVM 1246
>24326
          Length = 1186

 Score = 30.0 bits (66), Expect = 6.6,   Method: Compositional matrix adjust.
 Identities = 28/84 (33%), Positives = 36/84 (42%), Gaps = 4/84 (4%)
 Frame = -2

Query: 404 YVAW--LRDMFLQPDLNSLVDFSTANQK--RAQDASLNVPERAVFRLRKWIIHRLVSLVD 459
           YVAW   +D   Q  L  L + + A +K   A DAS  V      R   WII      +D
Sbjct: 453 YVAWGLKKDDADQQRLLQLEETARAAKKGKHADDASTRV------RDITWIIENPRHFID 292

Query: 460 HLHLEKDEAVVEQIARFCLFHAFF 483
             H +  EAV+E +   C   AF 
Sbjct: 291 SHHSKPVEAVIEHVRDGCTVRAFL 220
>13662
          Length = 654

 Score = 29.6 bits (65), Expect = 8.3,   Method: Compositional matrix adjust.
 Identities = 34/122 (27%), Positives = 56/122 (45%), Gaps = 4/122 (3%)
 Frame = +1

Query: 41  AKPDQETRLRATEKLLEY-LRTRPNDSEMKYALKRLITGLGVGREAARPCYSLALAQLLQ 99
           A+ D+   +R  EKLL+Y     PN           +  L + R    P   LA   +L 
Sbjct: 340 AETDETVEMRDKEKLLDYRFMPEPN-----------LPPLHICRRDTEPSLQLAADVILD 486

Query: 100 SF-EDIPL--CDILDQIQEKYSLQAMNKAMMRPSLFANLFGVLALFQSGRLVKDKEALMK 156
              E +P+   DI  ++Q++Y +   + A++         G+LALF+S  ++KDK+    
Sbjct: 487 EVAERLPVLPADIRARVQQQYDIPLTSAAIL-----IREEGMLALFES--IMKDKQHDKT 645

Query: 157 SV 158
           SV
Sbjct: 646 SV 651
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|111607430|ref|NP_034691.2| interleukin enhancer
binding factor 3 isoform 1 [Mus musculus]
         (911 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

02302                                                                  69   1e-11
22248                                                                  58   2e-08
27201                                                                  46   6e-05
05371                                                                  39   0.013
>02302
          Length = 1179

 Score = 68.6 bits (166), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 26/56 (46%), Positives = 43/56 (76%)
 Frame = -3

Query: 423 NQLKPGLQYKLISQTGPVHAPIFTMSVEVDGSNFEASGPSKKTAKLHVAVKVLQDM 478
           ++++PGL+++  SQ+GPVH+P+FTMSV+V+G NF  +GP+K+ AK+  A   L+  
Sbjct: 421 DEIEPGLEFRFESQSGPVHSPVFTMSVDVNGENFRGNGPTKRKAKMAAAESALRSF 254
>22248
          Length = 787

 Score = 57.8 bits (138), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 27/45 (60%), Positives = 36/45 (80%)
 Frame = +3

Query: 22  NDDRHVMAKHSSVYPTQEELEAVQNMVSHTERALKAVSDWIDEQE 66
           +DDRHV AKH+++YPT+ EL AVQ +VS  ERALK VSD++ E +
Sbjct: 573 SDDRHVNAKHAAIYPTEVELHAVQTIVSACERALKQVSDFLAESD 707
>27201
          Length = 515

 Score = 46.2 bits (108), Expect = 6e-05,   Method: Compositional matrix adjust.
 Identities = 19/56 (33%), Positives = 34/56 (60%)
 Frame = +2

Query: 211 LDRQKCLAALASLRHAKWFQARANGLKSCVIVIRVLRDLCTRVPTWGPLRGWPLEL 266
           +D++   + LA++RH +WF+  A+   S  ++IR+L+DL  R   + PL  W L+ 
Sbjct: 320 MDQKYMQSHLAAIRHTRWFEENAHH-SSIKVLIRILKDLTKRFDAFSPLSAWMLDF 484
>05371
          Length = 1247

 Score = 38.5 bits (88), Expect = 0.013,   Method: Compositional matrix adjust.
 Identities = 21/45 (46%), Positives = 25/45 (55%)
 Frame = +2

Query: 431 YKLISQTGPVHAPIFTMSVEVDGSNFEASGPSKKTAKLHVAVKVL 475
           Y+L+S  G VH P F M V V  ++ E  G SKK AK   A  VL
Sbjct: 59  YQLLSHEGSVHEPTFLMKVTVAENSAEGKGTSKKKAKHSAARAVL 193
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31543938|ref|NP_058076.2| vesicle-associated membrane
protein 4 [Mus musculus]
         (141 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

02964                                                                  65   1e-11
16746                                                                  65   1e-11
04498                                                                  65   1e-11
27286                                                                  30   0.50 
07814                                                                  26   4.6  
>02964
          Length = 832

 Score = 64.7 bits (156), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 29/63 (46%), Positives = 46/63 (73%)
 Frame = -3

Query: 50  NDKIKHVQNQVDEVIDVMQENITKVIERGERLDELQDKSESLSDNATAFSNRSKQLRRQM 109
           +D +  +Q+QV+EV  VM +NI KV+ERG+RL++L DK+E L  +A  F   S+++R++ 
Sbjct: 746 SDNVSKLQSQVNEVKGVMTQNIEKVMERGDRLEDLMDKTEELEASAHNFQKTSRRIRKKF 567

Query: 110 WWR 112
           WWR
Sbjct: 566 WWR 558
>16746
          Length = 340

 Score = 64.7 bits (156), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 27/52 (51%), Positives = 40/52 (76%)
 Frame = +1

Query: 63  VIDVMQENITKVIERGERLDELQDKSESLSDNATAFSNRSKQLRRQMWWRGC 114
           V+ +M++N+ +V ERG+RL++LQDKS+SLS +A  F +RSK L   MWW+ C
Sbjct: 1   VMGIMRDNVNRVAERGDRLEDLQDKSDSLSSSADMFRSRSKSLHHNMWWKNC 156
>04498
          Length = 1353

 Score = 64.7 bits (156), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 29/63 (46%), Positives = 46/63 (73%)
 Frame = +3

Query: 50  NDKIKHVQNQVDEVIDVMQENITKVIERGERLDELQDKSESLSDNATAFSNRSKQLRRQM 109
           +D +  +Q+QV+EV  VM +NI KV+ERG+RL++L DK+E L  +A  F   S+++R++ 
Sbjct: 84  SDNVSKLQSQVNEVKGVMTQNIEKVMERGDRLEDLMDKTEELEASAHNFQKTSRRIRKKF 263

Query: 110 WWR 112
           WWR
Sbjct: 264 WWR 272
>27286
          Length = 454

 Score = 29.6 bits (65), Expect = 0.50,   Method: Compositional matrix adjust.
 Identities = 11/24 (45%), Positives = 18/24 (75%)
 Frame = +1

Query: 60  VDEVIDVMQENITKVIERGERLDE 83
           VD  + + Q+++ KV++RG RLDE
Sbjct: 166 VDRFLHLFQQDVVKVVDRGHRLDE 237
>07814
          Length = 1888

 Score = 26.2 bits (56), Expect = 4.6,   Method: Composition-based stats.
 Identities = 12/34 (35%), Positives = 22/34 (64%), Gaps = 1/34 (2%)
 Frame = +3

Query: 47   GPRNDKIKHVQNQVDEVIDVMQ-ENITKVIERGE 79
            GPR  + +HV+ ++ +V  V Q  ++ ++ ERGE
Sbjct: 1206 GPRPHRPQHVRGKIVDVTTVQQ*MSVVRITERGE 1307
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|94368145|ref|XP_987046.1| PREDICTED: similar to golgi
autoantigen, golgin subfamily a, 4 [Mus musculus]
         (2333 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

14078                                                                  70   1e-11
08106                                                                  66   1e-10
30332                                                                  65   2e-10
30747                                                                  59   2e-08
20802                                                                  49   3e-05
15929                                                                  49   3e-05
17623                                                                  47   1e-04
19955                                                                  46   2e-04
19478                                                                  35   0.36 
20775                                                                  32   2.1  
28040                                                                  31   7.5  
34528                                                                  30   8.1  
>14078
          Length = 1045

 Score = 70.1 bits (170), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 44/116 (37%), Positives = 68/116 (58%)
 Frame = -1

Query: 152 LNLSYNKISKIEGLENMCNLQKLNLAGNEIEHIPVWFAKKLKSLRVLNLKGNKISSLQDV 211
           L L+ N I +IEGL     L  L+L  N++E +   F   LK L+ +NL+GN +SS++++
Sbjct: 352 LVLAANVIKRIEGLGRCAGLTTLHLRDNQLESLD-GFTDDLKELQYVNLRGNLMSSVKEM 176

Query: 212 SKLKPLQDLTSLVLIDNPVVALPHYLQFIIFHLRSLESLEGQPVTTQDRQEAFERF 267
           +KLK L  L +L L +NPV     Y   ++  LR+LE L+    T ++R EA E +
Sbjct: 175 TKLKCLSFLRALALSENPVADEDDYRMEVLIALRTLERLDKDEFTDEERHEAEEIY 8
>08106
          Length = 997

 Score = 66.2 bits (160), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 41/111 (36%), Positives = 67/111 (60%)
 Frame = +2

Query: 157 NKISKIEGLENMCNLQKLNLAGNEIEHIPVWFAKKLKSLRVLNLKGNKISSLQDVSKLKP 216
           N I +IEGL    +L  L+L  N++E++   F ++LK L+ +N++GN ++S+++ +KLK 
Sbjct: 8   NVIKRIEGLGRCVSLATLHLRDNQLENLD-GFTEELKELQYVNVRGNLLTSIKEAAKLKD 184

Query: 217 LQDLTSLVLIDNPVVALPHYLQFIIFHLRSLESLEGQPVTTQDRQEAFERF 267
           L  L +L L +NPV     Y   I+  LR LE L+    T ++R EA E +
Sbjct: 185 LPLLRALSLAENPVADEDDYRLEILIALRCLERLDKDEFTDEERHEAEEIY 337
>30332
          Length = 401

 Score = 65.5 bits (158), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 39/108 (36%), Positives = 64/108 (59%)
 Frame = +2

Query: 1499 QLRLLQADAEDLEQHKIKQEEILKEINKVVAAKDADFQCXXXXXXXXXXXXQSLQRDIKA 1558
            QL  ++A+ +DLE+ + KQE +LK+IN+V+A KD +F+             Q +Q D+  
Sbjct: 8    QLAQVKAELKDLERKRNKQERLLKDINQVIAKKDTEFRDLDSKVKAVQQSLQRVQEDLAL 187

Query: 1559 AQHSEDHHLQVLRESETLLQAKRAELETLKSQVTSQQQELAVLDSELG 1606
            +   E   +  LR+SE +L  +RAE+  ++ QV SQ+ EL  LD ++G
Sbjct: 188  STQREKETVDALRDSEDILGKRRAEIARMRDQVDSQRAELERLDQQVG 331
>30747
          Length = 1168

 Score = 59.3 bits (142), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 39/119 (32%), Positives = 64/119 (53%)
 Frame = +3

Query: 112 GKKFRYIENLEKCVKLEVLNLSYNLIVKIEKVDKLLRLRELNLSYNKISKIEGLENMCNL 171
           G   + + +L +C KL  L+LS N +V I  +  L  L+ L++S N++  +  L  + +L
Sbjct: 627 GNSIQKLTDLHRCKKLSELDLSRNRLVDISGISGLPALQTLDMSDNRLKSVTSLGKLKSL 806

Query: 172 QKLNLAGNEIEHIPVWFAKKLKSLRVLNLKGNKISSLQDVSKLKPLQDLTSLVLIDNPV 230
           + LNL GN+I  +  W       L++L L  N +++ + V  LK L DL  + L  NPV
Sbjct: 807 ETLNLNGNQISELLGW-GSCFPKLQILKLCDNMVTAWKQVCCLKELGDLNEVYLAGNPV 980

 Score = 50.4 bits (119), Expect = 8e-06,   Method: Compositional matrix adjust.
 Identities = 42/122 (34%), Positives = 71/122 (58%)
 Frame = +3

Query: 112 GKKFRYIENLEKCVKLEVLNLSYNLIVKIEKVDKLLRLRELNLSYNKISKIEGLENMCNL 171
           G +   + +LEK  KL VL++S N I KI+ ++    LR+L L  NK+S+++GLE++  L
Sbjct: 222 GTEITAVPDLEKFRKLRVLDVSGNYITKIQHLEFTQDLRDLKLYDNKVSQVQGLESLKEL 401

Query: 172 QKLNLAGNEIEHIPVWFAKKLKSLRVLNLKGNKISSLQDVSKLKPLQDLTSLVLIDNPVV 231
             L L  N+IE +       LK L+ L L  N+++ L D ++L    ++++L L +N + 
Sbjct: 402 CSLQLQYNQIESLGKGL-NALKKLKCLRLDSNRLTKL-DTNELLSCVNISTLDLSNNHIT 575

Query: 232 AL 233
            L
Sbjct: 576 NL 581
>20802
          Length = 526

 Score = 48.5 bits (114), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 40/121 (33%), Positives = 67/121 (55%)
 Frame = +2

Query: 83  ITEALIKKLTKQDNLALVKSLNLSLSKDGGKKFRYIENLEKCVKLEVLNLSYNLIVKIEK 142
           ITE +++K  + + L +     ++L +   ++  Y++  + C +L++L L  NLI KIE 
Sbjct: 131 ITEDMVRKRAEHNELEISTLEEVTLHQQDIERIEYLD--KWCRELKILYLQSNLIPKIEN 304

Query: 143 VDKLLRLRELNLSYNKISKIEGLENMCNLQKLNLAGNEIEHIPVWFAKKLKSLRVLNLKG 202
           V +L +L  LNL+ N + K+E LE   +L+KL+L  N        F  +L S+    LKG
Sbjct: 305 VSRLKKLEYLNLALNNVEKVENLEGCESLKKLDLTVN--------FVGELTSIEC--LKG 454

Query: 203 N 203
           N
Sbjct: 455 N 457
>15929
          Length = 1074

 Score = 48.5 bits (114), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 35/116 (30%), Positives = 58/116 (50%)
 Frame = +3

Query: 152 LNLSYNKISKIEGLENMCNLQKLNLAGNEIEHIPVWFAKKLKSLRVLNLKGNKISSLQDV 211
           ++ S N I K++G   +  L+ L L  N I  I     + + ++  + L  N I  L D+
Sbjct: 330 IDFSDNDIRKLDGFPLLKRLKSLLLNNNRIVRIVENLGEVIPNINTVVLTNNNIHELGDL 509

Query: 212 SKLKPLQDLTSLVLIDNPVVALPHYLQFIIFHLRSLESLEGQPVTTQDRQEAFERF 267
             L     L  L L+ NPV A  HY  ++IF + SL  L+ Q +  ++R++A + F
Sbjct: 510 DPLASFTKLEYLSLMRNPVNAKKHYRLYVIFKIPSLRVLDFQRIRLKEREQAAKLF 677
>17623
          Length = 687

 Score = 46.6 bits (109), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 37/93 (39%), Positives = 52/93 (55%), Gaps = 5/93 (5%)
 Frame = +2

Query: 159 ISKIEGLENMCNLQKLNLAGNEIEHIPVWFAKKLKSLRVLNLKGNKISSLQDVSKLKPLQ 218
           +  IE L ++ NL++LNLA N+IE +       +  L  LNL GN ISSL+DV+ L  L 
Sbjct: 296 LKNIENLTHLVNLKELNLAENKIEKLGHSLDSNIH-LEDLNLSGNPISSLRDVTNLVRLP 472

Query: 219 DLTSLVLID-----NPVVALPHYLQFIIFHLRS 246
            L S+ + D      PV  L +Y   I+FHL +
Sbjct: 473 QLQSVSMKDPLYRPCPVSQLCNYSTHILFHLPT 571

 Score = 33.9 bits (76), Expect = 0.75,   Method: Compositional matrix adjust.
 Identities = 20/48 (41%), Positives = 30/48 (62%)
 Frame = +1

Query: 137 IVKIEKVDKLLRLRELNLSYNKISKIEGLENMCNLQKLNLAGNEIEHI 184
           I  +  ++ L  L+EL ++  +I KIEGLE    ++KL L GN+I HI
Sbjct: 97  IPTLSGLNTLTNLKELWVAECQIKKIEGLEKCVLVEKLYLYGNQISHI 240

 Score = 32.7 bits (73), Expect = 1.8,   Method: Compositional matrix adjust.
 Identities = 26/64 (40%), Positives = 36/64 (56%), Gaps = 4/64 (6%)
 Frame = +2

Query: 115 FRYIENLEKCVKLEVLNLSYNLIVKIEK----VDKLLRLRELNLSYNKISKIEGLENMCN 170
            + IENL   V L+ LNL+ N   KIEK    +D  + L +LNLS N IS +  + N+  
Sbjct: 296 LKNIENLTHLVNLKELNLAEN---KIEKLGHSLDSNIHLEDLNLSGNPISSLRDVTNLVR 466

Query: 171 LQKL 174
           L +L
Sbjct: 467 LPQL 478
>19955
          Length = 634

 Score = 45.8 bits (107), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 27/62 (43%), Positives = 37/62 (59%)
 Frame = -2

Query: 118 IENLEKCVKLEVLNLSYNLIVKIEKVDKLLRLRELNLSYNKISKIEGLENMCNLQKLNLA 177
           I  L     L VL L  N I +IE +D L++L  L+L  N+I++IE L ++  L  LNLA
Sbjct: 186 IAGLSSLKSLRVLMLGKNRIKRIENLDTLIKLDVLDLHGNQITRIENLNHLGELLVLNLA 7

Query: 178 GN 179
           GN
Sbjct: 6   GN 1

 Score = 37.7 bits (86), Expect = 0.063,   Method: Compositional matrix adjust.
 Identities = 26/66 (39%), Positives = 38/66 (57%)
 Frame = -2

Query: 149 LRELNLSYNKISKIEGLENMCNLQKLNLAGNEIEHIPVWFAKKLKSLRVLNLKGNKISSL 208
           LR LN  +N I++I  L ++  L  L+L  N+IE I       LKSLRVL L  N+I  +
Sbjct: 291 LRLLNYQHNAITRINHLNSLRRLIFLDLYDNQIEQIAGL--SSLKSLRVLMLGKNRIKRI 118

Query: 209 QDVSKL 214
           +++  L
Sbjct: 117 ENLDTL 100

 Score = 37.4 bits (85), Expect = 0.063,   Method: Compositional matrix adjust.
 Identities = 20/47 (42%), Positives = 30/47 (63%)
 Frame = -2

Query: 111 GGKKFRYIENLEKCVKLEVLNLSYNLIVKIEKVDKLLRLRELNLSYN 157
           G  + + IENL+  +KL+VL+L  N I +IE ++ L  L  LNL+ N
Sbjct: 141 GKNRIKRIENLDTLIKLDVLDLHGNQITRIENLNHLGELLVLNLAGN 1
>19478
          Length = 846

 Score = 35.0 bits (79), Expect = 0.36,   Method: Compositional matrix adjust.
 Identities = 28/92 (30%), Positives = 48/92 (52%), Gaps = 1/92 (1%)
 Frame = -1

Query: 171 LQKLNLAGNEIEHIPVWFAKKLKSLRVLNLKGNKISSLQDVSKL-KPLQDLTSLVLIDNP 229
           L+ LN++GN +E +     + L++L  L    N+++ ++++S L      L  L L+ NP
Sbjct: 798 LEVLNISGNNLESLSD--LEILRALTQLFASDNQLNDMRELSDLLAAWPRLCRLELVGNP 625

Query: 230 VVALPHYLQFIIFHLRSLESLEGQPVTTQDRQ 261
           +   P Y   II   + L  L+G+ VT   RQ
Sbjct: 624 LCHKPKYKDRIIVMCKQLXMLDGKEVTDTTRQ 529
>20775
          Length = 1020

 Score = 32.3 bits (72), Expect = 2.1,   Method: Composition-based stats.
 Identities = 19/58 (32%), Positives = 29/58 (50%)
 Frame = -3

Query: 168 MCNLQKLNLAGNEIEHIPVWFAKKLKSLRVLNLKGNKISSLQDVSKLKPLQDLTSLVL 225
           M   ++LNLA N I+ I   F  ++  L  LNL  N +S +   +     Q L++L L
Sbjct: 301 MLGXKELNLASNAIDRIEDGFFSRMDKLTTLNLSDNHLSQVTQTTFSGLAQSLSTLDL 128
>28040
          Length = 433

 Score = 30.8 bits (68), Expect = 7.5,   Method: Compositional matrix adjust.
 Identities = 42/147 (28%), Positives = 69/147 (46%), Gaps = 9/147 (6%)
 Frame = +3

Query: 1985 TDQKSRLKQLLTDVSAAEGRLGTLQEEERRIEGLERMLSQAKQQLSEREQQLMAKSGELL 2044
            TD++S   Q+ + +S  E   GTL   +  +E L     Q K++LSERE+++      L 
Sbjct: 3    TDKESLGSQMSSMLSTMESLQGTLSARDSELEQLMSQTEQLKEKLSEREEEVTGLQASLG 182

Query: 2045 ALQKEADDMRADFSLLRNQFLTERKKAEKQVAGLKEALKIQRSQLEKNL-------LEQK 2097
            +LQ      ++D   +   +    +  E Q++ L++    +R QLE  L       LEQK
Sbjct: 183  SLQDVIAMTKSDLEAVTEDYNDRAQDLEAQISELEK----RRDQLETELETEKAKNLEQK 350

Query: 2098 QENSCM--QKEMATIELVAQDNHERAR 2122
            +E   M  Q+E A++      N  R R
Sbjct: 351  EELEKMIRQQEEASVTRTVSKNLTRPR 431
>34528
          Length = 621

 Score = 30.4 bits (67), Expect = 8.1,   Method: Compositional matrix adjust.
 Identities = 25/86 (29%), Positives = 47/86 (54%)
 Frame = +2

Query: 295 KFLEEIKNQDKLNKSLKEEAMLQKQSCEELESDLSTKKELLKQKTVELTRACQKQYELEQ 354
           K L+ +K + +L+  +  ++ L K+    L++  + K+ +LKQKTVEL   C ++  L +
Sbjct: 143 KRLQSLKKRPRLDAPVVPKSPLLKR----LQARAAMKRRMLKQKTVELVPECHERVPLRR 310

Query: 355 ELAFYKIDAKFEPLNYYPSEYAEIDK 380
           + +  K+     PL   P E AE+ +
Sbjct: 311 QKS-PKVKRTSLPL---PXEEAEVAR 376
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|10946854|ref|NP_067438.1| phosphoribosyl
pyrophosphate synthetase 1 [Mus musculus]
         (318 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

21831                                                                  65   2e-11
07115                                                                  29   3.2  
>21831
          Length = 1374

 Score = 65.5 bits (158), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 30/51 (58%), Positives = 39/51 (76%)
 Frame = -1

Query: 266 FEAVVVTNTIPQEDKMKHCSKIQVIDISMILAEAIRRTHNGESVSYLFSHV 316
           +  VVVTNT+P E K   C KI+ +DIS +LAEAIRR H+GES+SYLF ++
Sbjct: 813 YVQVVVTNTVPHEVKKMQCHKIKTVDISSLLAEAIRRIHHGESMSYLFRNI 661
>07115
          Length = 1190

 Score = 28.9 bits (63), Expect = 3.2,   Method: Compositional matrix adjust.
 Identities = 13/35 (37%), Positives = 24/35 (68%)
 Frame = +1

Query: 99  KKDKSRAPISAKLVANMLSVAGADHIITMDLHASQ 133
           K++K++AP++AK     +++    +I +MDLH SQ
Sbjct: 313 KQNKNKAPMAAKR*EQPITLLIYTNIFSMDLHKSQ 417
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|124517683|ref|NP_035005.2| neural cell adhesion
molecule 1 isoform 2 [Mus musculus]
         (725 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

29990                                                                  62   2e-11
20110                                                                  57   4e-08
13135                                                                  55   9e-08
27666                                                                  50   3e-06
11855                                                                  49   6e-06
38127                                                                  48   2e-05
08294                                                                  47   3e-05
36498                                                                  35   3e-04
36700                                                                  42   9e-04
32888                                                                  33   0.002
25766                                                                  39   0.005
06028                                                                  37   0.025
18345                                                                  36   0.045
20244                                                                  29   0.046
10921                                                                  36   0.047
35419                                                                  35   0.093
29932                                                                  35   0.13 
22019                                                                  34   0.26 
12764                                                                  34   0.27 
17678                                                                  33   0.40 
17530                                                                  33   0.50 
34811                                                                  32   0.90 
29881                                                                  32   1.3  
25455                                                                  31   1.9  
37675                                                                  30   3.6  
07940                                                                  29   8.2  
>29990
          Length = 434

 Score = 61.6 bits (148), Expect(2) = 2e-11,   Method: Composition-based stats.
 Identities = 38/107 (35%), Positives = 50/107 (46%), Gaps = 4/107 (3%)
 Frame = +3

Query: 147 PTIIWKHKGRDVILKKDVRFIVLSNNYLQIRGIKKTDEGTYRCEGRILARGEINFKDIQV 206
           P I+W H    V +  D RF +L +  L I   +  D G Y C  R +A GE +   +++
Sbjct: 18  PEIVWMHNNNRVEISGDSRFSLLHDGTLMIEDAQDDDRGVYECIARNVA-GETHSNQVEL 194

Query: 207 IV----NVPPTVQARQSIVNATANLGQSVTLVCDADGFPEPTMSWTK 249
                   P   Q  Q IV      GQ+V LVC A G P PT SWT+
Sbjct: 195 RYFGERVAPXFTQRPQDIVTVE---GQTVQLVCQASGHPRPTFSWTR 326

 Score = 25.4 bits (54), Expect(2) = 2e-11,   Method: Composition-based stats.
 Identities = 11/26 (42%), Positives = 15/26 (57%)
 Frame = +2

Query: 265 IFSDDSSELTIRNVDKNDEAEYVCIA 290
           I   +   LTIRNV ++D  +Y C A
Sbjct: 356 ITDHEDGTLTIRNVQESDRGDYQCYA 433

 Score = 44.7 bits (104), Expect = 2e-04,   Method: Composition-based stats.
 Identities = 29/88 (32%), Positives = 41/88 (46%), Gaps = 4/88 (4%)
 Frame = +3

Query: 273 LTIRNVDKNDEAEYVCIAENKAGEQDAS-IHLKVFAK---PKITYVENQTAMELEEQVTL 328
           L I +   +D   Y CIA N AGE  ++ + L+ F +   P  T           + V L
Sbjct: 99  LMIEDAQDDDRGVYECIARNVAGETHSNQVELRYFGERVAPXFTQRPQDIVTVEGQTVQL 278

Query: 329 TCEASGDPIPSITWRTSTRNISSEEKTL 356
            C+ASG P P+ +W   TRN+     TL
Sbjct: 279 VCQASGHPRPTFSW---TRNLEQLGSTL 353

 Score = 34.7 bits (78), Expect = 0.14,   Method: Composition-based stats.
 Identities = 26/104 (25%), Positives = 40/104 (38%), Gaps = 3/104 (2%)
 Frame = +3

Query: 51  DISWFSPNGEKLSPNQQRISVVWNDDDSSTLTIYNANIDDAGIYKCVVTAEDGTQSEATV 110
           +I W   N         R S++ +     TL I +A  DD G+Y+C+     G      V
Sbjct: 21  EIVWMHNNNRVEISGDSRFSLLHD----GTLMIEDAQDDDRGVYECIARNVAGETHSNQV 188

Query: 111 NVKIFQKLM---FKNAPTPQEFKEGEDAVIVCDVVSSLPPTIIW 151
            ++ F + +   F   P      EG+   +VC       PT  W
Sbjct: 189 ELRYFGERVAPXFTQRPQDIVTVEGQTVQLVCQASGHPRPTFSW 320
>20110
          Length = 820

 Score = 56.6 bits (135), Expect = 4e-08,   Method: Compositional matrix adjust.
 Identities = 44/153 (28%), Positives = 65/153 (42%), Gaps = 5/153 (3%)
 Frame = -1

Query: 174 LQIRGIKKTDEGTYRCEGRILARG--EINFKDIQVIVNVPPTVQARQSIVNATANLGQSV 231
           L +R + +TD G Y C  RI A    E   K   + V VPP+++   +        GQ+ 
Sbjct: 673 LVVRRLVETDAGIYTCTVRITAVSYEEWPTKIGNLTVQVPPSIKPGDTTAVLQIEQGQNS 494

Query: 232 TLVCDADGFPEPTMSWTKXXXXXXXXXXXXXKHIFSDDSSELTIRNVDKNDEAEYVCIAE 291
           TLVC A G P P ++WT+             +      S+ L + NV   D   Y C+A+
Sbjct: 493 TLVCAASGIPAPNITWTRSDGGFLPIGVAQFR------SATLPMNNVTVRDMGVYRCVAD 332

Query: 292 NKAGEQDASIHLK---VFAKPKITYVENQTAME 321
           N    +  + HL    VF  P    V+N    +
Sbjct: 331 NNI--KPPAEHLAEVLVFHAPFTRVVQNSVGQD 239

 Score = 41.6 bits (96), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 37/128 (28%), Positives = 53/128 (41%), Gaps = 8/128 (6%)
 Frame = -1

Query: 273 LTIRNVDKNDEAEYVCIAENKA---GEQDASI-HLKVFAKPKITYVENQTAMELEE--QV 326
           L +R + + D   Y C     A    E    I +L V   P I   +    +++E+    
Sbjct: 673 LVVRRLVETDAGIYTCTVRITAVSYEEWPTKIGNLTVQVPPSIKPGDTTAVLQIEQGQNS 494

Query: 327 TLTCEASGDPIPSITWRTSTRNISSEEKTLDGHMVVRSHA--RVSSLTLKSIQYTDAGEY 384
           TL C ASG P P+ITW  S           DG  +    A  R ++L + ++   D G Y
Sbjct: 493 TLVCAASGIPAPNITWTRS-----------DGGFLPIGVAQFRSATLPMNNVTVRDMGVY 347

Query: 385 ICTASNTI 392
            C A N I
Sbjct: 346 RCVADNNI 323

 Score = 29.6 bits (65), Expect = 4.3,   Method: Compositional matrix adjust.
 Identities = 20/87 (22%), Positives = 36/87 (41%)
 Frame = -1

Query: 30  EISVGESKFFLCQVAGDAKDKDISWFSPNGEKLSPNQQRISVVWNDDDSSTLTIYNANID 89
           +I  G++   +C  +G     +I+W   +G  L     +         S+TL + N  + 
Sbjct: 517 QIEQGQNSTLVCAASG-IPAPNITWTRSDGGFLPIGVAQFR-------SATLPMNNVTVR 362

Query: 90  DAGIYKCVVTAEDGTQSEATVNVKIFQ 116
           D G+Y+CV        +E    V +F 
Sbjct: 361 DMGVYRCVADNNIKPPAEHLAEVLVFH 281
>13135
          Length = 849

 Score = 55.1 bits (131), Expect = 9e-08,   Method: Compositional matrix adjust.
 Identities = 51/180 (28%), Positives = 80/180 (44%), Gaps = 7/180 (3%)
 Frame = -1

Query: 267 SDDSSELTIRNVDKNDEAEYVCIAENKAGEQDASIH-LKVFAKPKITYVENQTAMELEE- 324
           S  S  L I+N    DE  Y C  +        + H L +   P+I+ ++  + +   E 
Sbjct: 513 SPTSWRLRIQNGQVTDEGVYTCQVQLSNQNYAKAFHQLVIIQMPQISDLDTSSDVSKSEG 334

Query: 325 -QVTLTCEASGDPIPSITWRTSTRNISSEEKTLDGHMVVRSHARVSSLTLKSIQYTDAGE 383
             + L C ASG P PS+ W   TR ++ E     G    R H   S L +  ++   AG 
Sbjct: 333 QSLVLRCHASGRPTPSVKW---TR-MAGELLPSGG----REHLE-SDLVIPQLKPEHAGI 181

Query: 384 YICTASNTIGQDSQSMYLEVQYAPKLQGP-VAVYTWEGNQVNITCEVFAYPSAT---ISW 439
           Y C++SN+ G D +++ + V +AP L      V   +G    + C V  YP+     I+W
Sbjct: 180 YKCSSSNSAGSDFRNIRVTVNFAPVLSSANTVVQQAQGYVKELVCVVKGYPTPKADDITW 1

 Score = 48.1 bits (113), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 45/173 (26%), Positives = 73/173 (42%), Gaps = 4/173 (2%)
 Frame = -1

Query: 174 LQIRGIKKTDEGTYRCEGRILARGEINFKDIQVIVNVPPTVQARQSIVNATANLGQSVTL 233
           L+I+  + TDEG Y C+ ++  +         VI+ +P  +    +  + + + GQS+ L
Sbjct: 495 LRIQNGQVTDEGVYTCQVQLSNQNYAKAFHQLVIIQMP-QISDLDTSSDVSKSEGQSLVL 319

Query: 234 VCDADGFPEPTMSWTKXXXXXXXXXXXXXKHIFSDDSSELTIRNVDKNDEAEYVCIAENK 293
            C A G P P++ WT+             +H+ SD    L I  +       Y C + N 
Sbjct: 318 RCHASGRPTPSVKWTR--MAGELLPSGGREHLESD----LVIPQLKPEHAGIYKCSSSNS 157

Query: 294 AGEQDASIHLKVFAKPKITYVENQTAMELEEQVT-LTCEASGDPIPS---ITW 342
           AG    +I + V   P ++   N    + +  V  L C   G P P    ITW
Sbjct: 156 AGSDFRNIRVTVNFAPVLSSA-NTVVQQAQGYVKELVCVVKGYPTPKADDITW 1
>27666
          Length = 873

 Score = 50.4 bits (119), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 37/148 (25%), Positives = 63/148 (42%), Gaps = 5/148 (3%)
 Frame = +1

Query: 174 LQIRGIKKTDEGTYRCEGRILARGEINFKDIQVI----VNVPPTVQARQSIVNATANLGQ 229
           L IR +++ D GTY C+ +I  + E     +Q I    V VPP ++  ++      +  Q
Sbjct: 394 LVIRRLRQQDAGTYVCQVKI--QNENILSQVQKIGTLTVQVPPKIRPGETTTLVEIDQNQ 567

Query: 230 SVTLVCDADGFPEPTMSWTKXXXXXXXXXXXXXKHIFSDDSSELTIRNVDKNDEAEYVCI 289
           + +LVC + G P P ++WT+             +        EL +     +    Y C+
Sbjct: 568 NSSLVCSSTGIPAPNITWTRLDGRALPTGYSQFR------GRELPLNGATVDHMGVYRCV 729

Query: 290 AENKAGEQDASI-HLKVFAKPKITYVEN 316
           A N     D  +  ++VF  P    V+N
Sbjct: 730 ANNNIKPPDDHLCEVRVFHAPTARTVQN 813

 Score = 44.7 bits (104), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 43/144 (29%), Positives = 60/144 (41%), Gaps = 9/144 (6%)
 Frame = +1

Query: 273 LTIRNVDKNDEAEYVCIA----ENKAGEQDASIHLKVFAKPKITYVENQTAMELEEQ--V 326
           L IR + + D   YVC      EN   +      L V   PKI   E  T +E+++    
Sbjct: 394 LVIRRLRQQDAGTYVCQVKIQNENILSQVQKIGTLTVQVPPKIRPGETTTLVEIDQNQNS 573

Query: 327 TLTCEASGDPIPSITWRTSTRNISSEEKTLDGHMVVRSHA--RVSSLTLKSIQYTDAGEY 384
           +L C ++G P P+ITW   TR        LDG  +   ++  R   L L        G Y
Sbjct: 574 SLVCSSTGIPAPNITW---TR--------LDGRALPTGYSQFRGRELPLNGATVDHMGVY 720

Query: 385 ICTASNTIG-QDSQSMYLEVQYAP 407
            C A+N I   D     + V +AP
Sbjct: 721 RCVANNNIKPPDDHLCEVRVFHAP 792

 Score = 41.6 bits (96), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 33/125 (26%), Positives = 54/125 (43%), Gaps = 8/125 (6%)
 Frame = +1

Query: 370 SLTLKSIQYTDAGEYICTAS----NTIGQDSQSMYLEVQYAPKLQGPVAVYTWEGNQ--- 422
           +L ++ ++  DAG Y+C       N + Q  +   L VQ  PK++        E +Q   
Sbjct: 391 TLVIRRLRQQDAGTYVCQVKIQNENILSQVQKIGTLTVQVPPKIRPGETTTLVEIDQNQN 570

Query: 423 VNITCEVFAYPSATISWFR-DGQLLPSSNYSNIKIYNTPSASYLEVTPDSENDFGNYNCT 481
            ++ C     P+  I+W R DG+ LP+  YS  +         L +   + +  G Y C 
Sbjct: 571 SSLVCSSTGIPAPNITWTRLDGRALPTG-YSQFR------GRELPLNGATVDHMGVYRCV 729

Query: 482 AVNRI 486
           A N I
Sbjct: 730 ANNNI 744

 Score = 30.0 bits (66), Expect = 3.0,   Method: Compositional matrix adjust.
 Identities = 29/121 (23%), Positives = 45/121 (37%), Gaps = 6/121 (4%)
 Frame = +1

Query: 75  DDDSSTLTIYNANIDDAGIYKCVVTAED-----GTQSEATVNVKIFQKLMFKNAPTPQEF 129
           D  + TL I      DAG Y C V  ++       Q   T+ V++  K+      T  E 
Sbjct: 376 DRLTFTLVIRRLRQQDAGTYVCQVKIQNENILSQVQKIGTLTVQVPPKIRPGETTTLVEI 555

Query: 130 KEGEDAVIVCDVVSSLPPTIIW-KHKGRDVILKKDVRFIVLSNNYLQIRGIKKTDEGTYR 188
            + +++ +VC       P I W +  GR +       +       L + G      G YR
Sbjct: 556 DQNQNSSLVCSSTGIPAPNITWTRLDGRAL----PTGYSQFRGRELPLNGATVDHMGVYR 723

Query: 189 C 189
           C
Sbjct: 724 C 726
>11855
          Length = 1574

 Score = 49.3 bits (116), Expect = 6e-06,   Method: Compositional matrix adjust.
 Identities = 49/197 (24%), Positives = 74/197 (37%), Gaps = 35/197 (17%)
 Frame = +1

Query: 334 GDPIPSITW-RTSTRNISSEEKTLD-------------GHMVVRSHARVSSLTLKSIQYT 379
           G P+P+I W +   R   S  +T+D             G   +R  +  S L L      
Sbjct: 1   GSPVPTIHWLKDGVRLTQSTYETVDDESALYEDLASDPGQPRLRLSSTKSRLYLDCPTSQ 180

Query: 380 DAGEYICTASNTIGQDSQSMYLEV---QYAPKLQG---------PVAVYTW-------EG 420
           D GEY C A     +  QS  ++V    Y+P +           P  VY W       E 
Sbjct: 181 DEGEYTCVAETPFKRRVQSTIVKVDTRHYSPDVTCMSKRGSRGEPARVYMWTVSRLELET 360

Query: 421 NQVNITCEVFAYPSATISWF--RDGQLLPSSNYSNIKIYNTPSASYLEVTPDSENDFGNY 478
             V + C    YP  TI+W+  R+  L  +S   +I +    +   +        + G Y
Sbjct: 361 TTVQLFCRASGYPEPTITWYDGRNNSLPDNSGQFSIAV----NGDLIIRDISWSENMGVY 528

Query: 479 NCTAVNRIGQESLEFIL 495
            C A N +G  S++  L
Sbjct: 529 RCVAENELGSHSVQAFL 579

 Score = 44.3 bits (103), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 43/155 (27%), Positives = 62/155 (40%), Gaps = 19/155 (12%)
 Frame = +1

Query: 266 FSDDSSELTIRNVDKNDEAEYVCIAENKAGEQDASIHLKVFAK----------------- 308
            S   S L +      DE EY C+AE     +  S  +KV  +                 
Sbjct: 133 LSSTKSRLYLDCPTSQDEGEYTCVAETPFKRRVQSTIVKVDTRHYSPDVTCMSKRGSRGE 312

Query: 309 PKITYVENQTAMELEEQ-VTLTCEASGDPIPSITWRTSTRNISSEEKTLDGHMVVRSHAR 367
           P   Y+   + +ELE   V L C ASG P P+ITW    RN S  + +    + V     
Sbjct: 313 PARVYMWTVSRLELETTTVQLFCRASGYPEPTITWYDG-RNNSLPDNSGQFSIAVN---- 477

Query: 368 VSSLTLKSIQYTD-AGEYICTASNTIGQDSQSMYL 401
              L ++ I +++  G Y C A N +G  S   +L
Sbjct: 478 -GDLIIRDISWSENMGVYRCVAENELGSHSVQAFL 579

 Score = 34.3 bits (77), Expect = 0.18,   Method: Compositional matrix adjust.
 Identities = 21/75 (28%), Positives = 31/75 (41%), Gaps = 1/75 (1%)
 Frame = +1

Query: 230 SVTLVCDADGFPEPTMSWTKXXXXXXXXXXXXXKHIFSDDSSELTIRNVD-KNDEAEYVC 288
           +V L C A G+PEPT++W                   + D   L IR++    +   Y C
Sbjct: 364 TVQLFCRASGYPEPTITWYDGRNNSLPDNSGQFSIAVNGD---LIIRDISWSENMGVYRC 534

Query: 289 IAENKAGEQDASIHL 303
           +AEN+ G       L
Sbjct: 535 VAENELGSHSVQAFL 579
>38127
          Length = 860

 Score = 47.8 bits (112), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 31/125 (24%), Positives = 56/125 (44%), Gaps = 6/125 (4%)
 Frame = -1

Query: 273 LTIRNVDKNDEAEYVCIAENKAGEQDASIHLKV--FAKPKITYVENQTAMELEEQVTLTC 330
           L I++  +N    Y C+AE +     +SI + V  +A PK+   +    +  +E + + C
Sbjct: 797 LEIQHPRRNFAGMYTCVAEYEEAGVKSSISVDVPFYAHPKVLPFDKSKNLVQDESLVIEC 618

Query: 331 EASGDPIPSITWRTSTRNISSEEKTLDGHMVVRSHARVS----SLTLKSIQYTDAGEYIC 386
           +  G P P ++W      I     +        S+   S     L ++ +Q+ DAGEY C
Sbjct: 617 KVLGYPKPVVSWYMDNVEIVDGADSRYSLKPANSYDGASIEGAKLVIEEVQFDDAGEYTC 438

Query: 387 TASNT 391
            ++ T
Sbjct: 437 MSNYT 423

 Score = 35.8 bits (81), Expect = 0.057,   Method: Compositional matrix adjust.
 Identities = 30/124 (24%), Positives = 53/124 (42%), Gaps = 11/124 (8%)
 Frame = -1

Query: 77  DSSTLTIYNANIDDAGIYKCVVTAED-GTQSEATVNVKIFQKLMFKNAPTPQEFKEGEDA 135
           ++ TL I +   + AG+Y CV   E+ G +S  +V+V  +           +   + E  
Sbjct: 809 NNGTLEIQHPRRNFAGMYTCVAEYEEAGVKSSISVDVPFYAHPKVLPFDKSKNLVQDESL 630

Query: 136 VIVCDVVSSLPPTIIWKHKGRDVILKKDVRF-IVLSNNY---------LQIRGIKKTDEG 185
           VI C V+    P + W     +++   D R+ +  +N+Y         L I  ++  D G
Sbjct: 629 VIECKVLGYPKPVVSWYMDNVEIVDGADSRYSLKPANSYDGASIEGAKLVIEEVQFDDAG 450

Query: 186 TYRC 189
            Y C
Sbjct: 449 EYTC 438

 Score = 35.0 bits (79), Expect = 0.11,   Method: Compositional matrix adjust.
 Identities = 33/144 (22%), Positives = 58/144 (40%), Gaps = 9/144 (6%)
 Frame = -1

Query: 156 RDVILKKDVRFIVLSNNYLQIRGIKKTDEGTYRCEGRILARGEINFKDIQVIVNVPPTVQ 215
           +D+ +    R+I  +N  L+I+  ++   G Y C    +A  E       + V+VP    
Sbjct: 851 KDIKVDGKERYIQHNNGTLEIQHPRRNFAGMYTC----VAEYEEAGVKSSISVDVPFYAH 684

Query: 216 ARQSIVNATANLGQSVTLV--CDADGFPEPTMSW-------TKXXXXXXXXXXXXXKHIF 266
            +    + + NL Q  +LV  C   G+P+P +SW                          
Sbjct: 683 PKVLPFDKSKNLVQDESLVIECKVLGYPKPVVSWYMDNVEIVDGADSRYSLKPANSYDGA 504

Query: 267 SDDSSELTIRNVDKNDEAEYVCIA 290
           S + ++L I  V  +D  EY C++
Sbjct: 503 SIEGAKLVIEEVQFDDAGEYTCMS 432
>08294
          Length = 1849

 Score = 46.6 bits (109), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 30/112 (26%), Positives = 50/112 (44%), Gaps = 3/112 (2%)
 Frame = +2

Query: 285 EYVCIAEN-KAGEQDASIHLKVFAKPKITYVENQTAMELEEQVTLTCEASGDPIPSITWR 343
           +Y C+A + + G  +A+IH+ +   P IT   N   +       L C A G P P I W 
Sbjct: 2   DYTCVATHPRQGVINATIHISIVEWPAITVKSNNITVFEGHSAILHCVAKGSPSPDIAWY 181

Query: 344 TSTRNI--SSEEKTLDGHMVVRSHARVSSLTLKSIQYTDAGEYICTASNTIG 393
             ++ I  ++   TL          +  ++ ++ +   D G Y C A+NT G
Sbjct: 182 RDSQPILPNARRYTL---------FKNGTMKIRQVFMEDNGMYACVANNTAG 310

 Score = 35.4 bits (80), Expect = 0.086,   Method: Compositional matrix adjust.
 Identities = 29/109 (26%), Positives = 43/109 (39%)
 Frame = +2

Query: 187 YRCEGRILARGEINFKDIQVIVNVPPTVQARQSIVNATANLGQSVTLVCDADGFPEPTMS 246
           Y C      +G IN   I + +   P +  + +  N T   G S  L C A G P P ++
Sbjct: 5   YTCVATHPRQGVIN-ATIHISIVEWPAITVKSN--NITVFEGHSAILHCVAKGSPSPDIA 175

Query: 247 WTKXXXXXXXXXXXXXKHIFSDDSSELTIRNVDKNDEAEYVCIAENKAG 295
           W +               +F + +  + IR V   D   Y C+A N AG
Sbjct: 176 WYRDSQPILPNARRYT--LFKNGT--MKIRQVFMEDNGMYACVANNTAG 310

 Score = 31.2 bits (69), Expect = 1.4,   Method: Compositional matrix adjust.
 Identities = 21/74 (28%), Positives = 32/74 (43%), Gaps = 1/74 (1%)
 Frame = +2

Query: 415 VYTWEGNQVNITCEVFAYPSATISWFRDGQ-LLPSSNYSNIKIYNTPSASYLEVTPDSEN 473
           +  +EG+   + C     PS  I+W+RD Q +LP     N + Y       +++      
Sbjct: 104 ITVFEGHSAILHCVAKGSPSPDIAWYRDSQPILP-----NARRYTLFKNGTMKIRQVFME 268

Query: 474 DFGNYNCTAVNRIG 487
           D G Y C A N  G
Sbjct: 269 DNGMYACVANNTAG 310
>36498
          Length = 478

 Score = 32.0 bits (71), Expect(2) = 3e-04,   Method: Composition-based stats.
 Identities = 21/78 (26%), Positives = 33/78 (42%), Gaps = 5/78 (6%)
 Frame = +3

Query: 369 SSLTLKSIQYTDAGEYICTASNTIGQDSQSMYLEVQ---YAPK--LQGPVAVYTWEGNQV 423
           + L    +   DAG Y+C A N  G   +++ L V     AP+  + GP      +G  V
Sbjct: 225 AGLRFDPVSEGDAGRYVCVARNERGITEENVDLTVTRTGVAPQVNIDGPGRQMLVDGQSV 404

Query: 424 NITCEVFAYPSATISWFR 441
            ++C      +  I W R
Sbjct: 405 ELSCSARGLRNPLIRWRR 458

 Score = 30.8 bits (68), Expect(2) = 3e-04,   Method: Composition-based stats.
 Identities = 16/53 (30%), Positives = 24/53 (45%), Gaps = 1/53 (1%)
 Frame = +1

Query: 292 NKAGEQDASIHLKVFAKPKITYVENQTAMEL-EEQVTLTCEASGDPIPSITWR 343
           N AG    +  L +   P +T         L  ++V + C A GDP P++ WR
Sbjct: 1   NAAGTVTLTASLVIQGPPTVTVTPGTRITALVGDRVDIECVAEGDPTPTVFWR 159

 Score = 34.7 bits (78), Expect = 0.14,   Method: Composition-based stats.
 Identities = 23/73 (31%), Positives = 34/73 (46%), Gaps = 4/73 (5%)
 Frame = +3

Query: 278 VDKNDEAEYVCIAENKAGEQDASIHLKVF---AKPKITYVENQTAMELEEQ-VTLTCEAS 333
           V + D   YVC+A N+ G  + ++ L V      P++        M ++ Q V L+C A 
Sbjct: 246 VSEGDAGRYVCVARNERGITEENVDLTVTRTGVAPQVNIDGPGRQMLVDGQSVELSCSAR 425

Query: 334 GDPIPSITWRTST 346
           G   P I WR  T
Sbjct: 426 GLRNPLIRWRRPT 464

 Score = 30.0 bits (66), Expect = 3.6,   Method: Composition-based stats.
 Identities = 26/85 (30%), Positives = 38/85 (44%), Gaps = 9/85 (10%)
 Frame = +3

Query: 174 LQIRGIKKTDEGTYRCEGRILARGE--INFKDIQVIVN---VPPTVQ----ARQSIVNAT 224
           L+   + + D G Y C    +AR E  I  +++ + V    V P V      RQ +V+  
Sbjct: 231 LRFDPVSEGDAGRYVC----VARNERGITEENVDLTVTRTGVAPQVNIDGPGRQMLVD-- 392

Query: 225 ANLGQSVTLVCDADGFPEPTMSWTK 249
              GQSV L C A G   P + W +
Sbjct: 393 ---GQSVELSCSARGLRNPLIRWRR 458
>36700
          Length = 595

 Score = 42.0 bits (97), Expect = 9e-04,   Method: Compositional matrix adjust.
 Identities = 18/42 (42%), Positives = 23/42 (54%)
 Frame = +1

Query: 268 DDSSELTIRNVDKNDEAEYVCIAENKAGEQDASIHLKVFAKP 309
           D+   L I NVD+ DE  Y C  EN AG    ++HL V + P
Sbjct: 133 DNGRVLVIDNVDEQDEKTYTCKGENPAGSHSGNLHLNVTSPP 258
>32888
          Length = 418

 Score = 33.5 bits (75), Expect(2) = 0.002,   Method: Compositional matrix adjust.
 Identities = 15/34 (44%), Positives = 21/34 (61%)
 Frame = -2

Query: 371 LTLKSIQYTDAGEYICTASNTIGQDSQSMYLEVQ 404
           LT+KS+   D G Y C  SNT GQ   + Y++V+
Sbjct: 114 LTIKSLGAEDKGNYTCIVSNTEGQIDWTFYVDVE 13

 Score = 26.2 bits (56), Expect(2) = 0.002,   Method: Compositional matrix adjust.
 Identities = 16/50 (32%), Positives = 21/50 (42%), Gaps = 1/50 (2%)
 Frame = -3

Query: 320 MELEEQ-VTLTCEASGDPIPSITWRTSTRNISSEEKTLDGHMVVRSHARV 368
           +E E Q V L C A G P P +TW              +GH++     RV
Sbjct: 245 LEDEGQTVRLDCRAKGKPSPKVTW------------YKNGHIITNGDDRV 132

 Score = 29.6 bits (65), Expect(2) = 0.010,   Method: Compositional matrix adjust.
 Identities = 12/38 (31%), Positives = 21/38 (55%)
 Frame = -2

Query: 268 DDSSELTIRNVDKNDEAEYVCIAENKAGEQDASIHLKV 305
           D   +LTI+++   D+  Y CI  N  G+ D + ++ V
Sbjct: 129 DQKYKLTIKSLGAEDKGNYTCIVSNTEGQIDWTFYVDV 16

 Score = 27.7 bits (60), Expect(2) = 0.010,   Method: Compositional matrix adjust.
 Identities = 11/22 (50%), Positives = 14/22 (63%)
 Frame = -3

Query: 228 GQSVTLVCDADGFPEPTMSWTK 249
           GQ+V L C A G P P ++W K
Sbjct: 233 GQTVRLDCRAKGKPSPKVTWYK 168
>25766
          Length = 469

 Score = 36.6 bits (83), Expect(2) = 0.005,   Method: Compositional matrix adjust.
 Identities = 20/74 (27%), Positives = 31/74 (41%)
 Frame = +1

Query: 81  LTIYNANIDDAGIYKCVVTAEDGTQSEATVNVKIFQKLMFKNAPTPQEFKEGEDAVIVCD 140
           L I      DAG Y+CV+T+ +G  SE    ++I    +       +  + G      CD
Sbjct: 67  LQIPRVTAADAGRYRCVITSSEGITSEGFATLRISSPPVVSVKQRNENRQVGSSVKFHCD 246

Query: 141 VVSSLPPTIIWKHK 154
           V     P + W+ K
Sbjct: 247 VSGDPVPQVRWEKK 288

 Score = 21.9 bits (45), Expect(2) = 0.005,   Method: Composition-based stats.
 Identities = 9/21 (42%), Positives = 12/21 (57%)
 Frame = +3

Query: 169 LSNNYLQIRGIKKTDEGTYRC 189
           + N  L +  I+K DEG Y C
Sbjct: 315 IRNGILTLYNIQKEDEGRYIC 377

 Score = 39.3 bits (90), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 27/84 (32%), Positives = 36/84 (42%), Gaps = 5/84 (5%)
 Frame = +1

Query: 171 NNYLQIRGIKKTDEGTYRC-----EGRILARGEINFKDIQVIVNVPPTVQARQSIVNATA 225
           +  LQI  +   D G YRC     EG I + G    +     ++ PP V  +Q   N   
Sbjct: 58  DGILQIPRVTAADAGRYRCVITSSEG-ITSEGFATLR-----ISSPPVVSVKQR--NENR 213

Query: 226 NLGQSVTLVCDADGFPEPTMSWTK 249
            +G SV   CD  G P P + W K
Sbjct: 214 QVGSSVKFHCDVSGDPVPQVRWEK 285

 Score = 37.7 bits (86), Expect = 0.018,   Method: Compositional matrix adjust.
 Identities = 18/84 (21%), Positives = 34/84 (40%), Gaps = 1/84 (1%)
 Frame = +1

Query: 273 LTIRNVDKNDEAEYVCIAENKAG-EQDASIHLKVFAKPKITYVENQTAMELEEQVTLTCE 331
           L I  V   D   Y C+  +  G   +    L++ + P ++  +     ++   V   C+
Sbjct: 67  LQIPRVTAADAGRYRCVITSSEGITSEGFATLRISSPPVVSVKQRNENRQVGSSVKFHCD 246

Query: 332 ASGDPIPSITWRTSTRNISSEEKT 355
            SGDP+P + W     N     ++
Sbjct: 247 VSGDPVPQVRWEKKVDNCQRNTRS 318

 Score = 33.1 bits (74), Expect = 0.38,   Method: Composition-based stats.
 Identities = 19/46 (41%), Positives = 23/46 (50%)
 Frame = +3

Query: 358 GHMVVRSHARVSSLTLKSIQYTDAGEYICTASNTIGQDSQSMYLEV 403
           G +  +   R   LTL +IQ  D G YICTAS+  G D     L V
Sbjct: 291 GQLPAQHQIRNGILTLYNIQKEDEGRYICTASSENGVDRDYSNLRV 428
>06028
          Length = 1358

 Score = 37.0 bits (84), Expect = 0.025,   Method: Compositional matrix adjust.
 Identities = 65/271 (23%), Positives = 95/271 (35%), Gaps = 27/271 (9%)
 Frame = +1

Query: 52  ISWFSPNGEKLSPNQQRISVVWNDDDSSTLTIYNANIDDAGIYKCVVTAEDGTQSEAT-- 109
           I W    G +   N ++   V   D  S L I+N    D+G+Y CV + E G Q++ +  
Sbjct: 4   IQWMK--GTEPISNDEKYQQVDQADGYSKLIIHNPVEKDSGVYFCVASNE-GAQNKISHQ 174

Query: 110 VNVKIFQKL-------MFKNAPTPQEFKEGEDAVIVCD----------VVSSLPPTIIWK 152
           V+ K  ++         F   P    F        VC           + SS P  + W 
Sbjct: 175 VDFKGRERFTLEKTAGFFHRDPNKPHFLNPLGNQTVCHGGTVAISAEFMQSSTPIEVKWL 354

Query: 153 HKGRDVILKKDVRFIVLSNNYLQIRGIKKTDEGTYRCE-----GRILARGEINFKDIQVI 207
              R V       F       L I    +  EGTY C      GRI +   I   D+ V 
Sbjct: 355 RNRRPVDGPSVQTFNERGIYTLAIMNAGEEHEGTYTCLASNAFGRIESHVNI---DVAVG 525

Query: 208 VN---VPPTVQARQSIVNATANLGQSVTLVCDADGFPEPTMSWTKXXXXXXXXXXXXXKH 264
           V     PP   +R       A +G   +L     G P+P + + K             + 
Sbjct: 526 VEKEVRPPLFLSRPETEMKIA-VGDPFSLSFRIAGDPKPRLVFMKGTKDITQSDRVSKE- 699

Query: 265 IFSDDSSELTIRNVDKNDEAEYVCIAENKAG 295
             SDD +  T++    +D   Y  +A N  G
Sbjct: 700 -VSDDYTRFTVQKSQISDSGTYFVVARNDFG 789

 Score = 31.2 bits (69), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 37/169 (21%), Positives = 61/169 (36%), Gaps = 20/169 (11%)
 Frame = +1

Query: 340 ITWRTSTRNISSEEKTLDGHMVVRSHARVSSLTLKSIQYTDAGEYICTASNTIGQDSQSM 399
           I W   T  IS++EK    +  V      S L + +    D+G Y C ASN   Q+  S 
Sbjct: 4   IQWMKGTEPISNDEK----YQQVDQADGYSKLIIHNPVEKDSGVYFCVASNEGAQNKISH 171

Query: 400 YLEVQ------------------YAPKLQGPVAVYT-WEGNQVNITCEVFAYPSAT-ISW 439
            ++ +                    P    P+   T   G  V I+ E     +   + W
Sbjct: 172 QVDFKGRERFTLEKTAGFFHRDPNKPHFLNPLGNQTVCHGGTVAISAEFMQSSTPIEVKW 351

Query: 440 FRDGQLLPSSNYSNIKIYNTPSASYLEVTPDSENDFGNYNCTAVNRIGQ 488
            R+ + +   +  +++ +N      L +    E   G Y C A N  G+
Sbjct: 352 LRNRRPV---DGPSVQTFNERGIYTLAIMNAGEEHEGTYTCLASNAFGR 489
>18345
          Length = 461

 Score = 36.2 bits (82), Expect = 0.045,   Method: Composition-based stats.
 Identities = 18/71 (25%), Positives = 37/71 (52%)
 Frame = +1

Query: 81  LTIYNANIDDAGIYKCVVTAEDGTQSEATVNVKIFQKLMFKNAPTPQEFKEGEDAVIVCD 140
           L I +  ++D G+Y+C +  +     + T+ V++   ++ + +P     KEG+ A +VC+
Sbjct: 4   LLIRHVRLNDTGVYECRINTQPSQIKQVTLVVQVPPVVLSEGSPDRVSLKEGDTATLVCN 183

Query: 141 VVSSLPPTIIW 151
           V     P + W
Sbjct: 184 VTGVPSPDVTW 216

 Score = 33.1 bits (74), Expect = 0.44,   Method: Composition-based stats.
 Identities = 34/119 (28%), Positives = 51/119 (42%)
 Frame = +1

Query: 174 LQIRGIKKTDEGTYRCEGRILARGEINFKDIQVIVNVPPTVQARQSIVNATANLGQSVTL 233
           L IR ++  D G Y C  RI  +     K + ++V VPP V +  S    +   G + TL
Sbjct: 4   LLIRHVRLNDTGVYEC--RINTQPS-QIKQVTLVVQVPPVVLSEGSPDRVSLKEGDTATL 174

Query: 234 VCDADGFPEPTMSWTKXXXXXXXXXXXXXKHIFSDDSSELTIRNVDKNDEAEYVCIAEN 292
           VC+  G P P ++W K             K         L + NV ++ +  Y C A+N
Sbjct: 175 VCNVTGVPSPDVTWYK----RNTRQLDAQKERVGSTGPVLVMYNVTRHCDDIYECYADN 339

 Score = 30.8 bits (68), Expect = 2.0,   Method: Composition-based stats.
 Identities = 30/143 (20%), Positives = 65/143 (45%), Gaps = 3/143 (2%)
 Frame = +1

Query: 273 LTIRNVDKNDEAEYVCIAENKAGE-QDASIHLKVFAKPKITYVENQTAMELEEQVTLTCE 331
           L IR+V  ND   Y C    +  + +  ++ ++V          ++ +++  +  TL C 
Sbjct: 4   LLIRHVRLNDTGVYECRINTQPSQIKQVTLVVQVPPVVLSEGSPDRVSLKEGDTATLVCN 183

Query: 332 ASGDPIPSITW-RTSTRNISSEEKTLDGHMVVRSHARVSSLTLKSIQYTDAGEYICTASN 390
            +G P P +TW + +TR + ++++        R  +    L + ++       Y C A N
Sbjct: 184 VTGVPSPDVTWYKRNTRQLDAQKE--------RVGSTGPVLVMYNVTRHCDDIYECYADN 339

Query: 391 TIGQD-SQSMYLEVQYAPKLQGP 412
            +    ++++ + V YAP++  P
Sbjct: 340 GVPPAVTKAIRVTVDYAPEVHLP 408
>20244
          Length = 452

 Score = 29.3 bits (64), Expect(2) = 0.046,   Method: Compositional matrix adjust.
 Identities = 11/25 (44%), Positives = 18/25 (72%)
 Frame = -3

Query: 165 RFIVLSNNYLQIRGIKKTDEGTYRC 189
           R+++ SN  L I  +++TD+GTY C
Sbjct: 303 RYVLTSNGDLTIVQVRQTDDGTYVC 229

 Score = 25.8 bits (55), Expect(2) = 0.046,   Method: Compositional matrix adjust.
 Identities = 7/22 (31%), Positives = 12/22 (54%)
 Frame = -2

Query: 228 GQSVTLVCDADGFPEPTMSWTK 249
           G ++   C   G+P P ++WT 
Sbjct: 121 GSTIAFNCSVQGYPTPNVTWTN 56

 Score = 26.6 bits (57), Expect(2) = 3.1,   Method: Composition-based stats.
 Identities = 11/22 (50%), Positives = 16/22 (72%)
 Frame = -1

Query: 328 LTCEASGDPIPSITWRTSTRNI 349
           L C A+G+P P+ITW  S +N+
Sbjct: 383 LRCFATGNPAPNITW--SLKNV 324

 Score = 21.9 bits (45), Expect(2) = 3.1,   Method: Compositional matrix adjust.
 Identities = 16/62 (25%), Positives = 30/62 (48%), Gaps = 6/62 (9%)
 Frame = -2

Query: 384 YICT-ASNTIGQDSQSMYLEVQYAPKLQGPVAV-----YTWEGNQVNITCEVFAYPSATI 437
           Y+C  ASN +G+  +   +E+Q     +  + +     YT  G+ +   C V  YP+  +
Sbjct: 241 YLCLLASNGLGEPVRRE-VELQVTVNAEAVIGLDPQNSYT-PGSTIAFNCSVQGYPTPNV 68

Query: 438 SW 439
           +W
Sbjct: 67  TW 62

 Score = 26.2 bits (56), Expect(2) = 6.6,   Method: Compositional matrix adjust.
 Identities = 17/66 (25%), Positives = 30/66 (45%), Gaps = 4/66 (6%)
 Frame = -2

Query: 286 YVCI-AENKAGE---QDASIHLKVFAKPKITYVENQTAMELEEQVTLTCEASGDPIPSIT 341
           Y+C+ A N  GE   ++  + + V A+  I  ++ Q +      +   C   G P P++T
Sbjct: 241 YLCLLASNGLGEPVRREVELQVTVNAEAVIG-LDPQNSYTPGSTIAFNCSVQGYPTPNVT 65

Query: 342 WRTSTR 347
           W    R
Sbjct: 64  WTNG*R 47

 Score = 21.6 bits (44), Expect(2) = 6.6,   Method: Composition-based stats.
 Identities = 8/21 (38%), Positives = 11/21 (52%)
 Frame = -1

Query: 228 GQSVTLVCDADGFPEPTMSWT 248
           G    L C A G P P ++W+
Sbjct: 398 GGIAVLRCFATGNPAPNITWS 336
>10921
          Length = 525

 Score = 36.2 bits (82), Expect = 0.047,   Method: Compositional matrix adjust.
 Identities = 26/80 (32%), Positives = 35/80 (43%), Gaps = 1/80 (1%)
 Frame = -2

Query: 264 HIFSDDSSELTIRNVDKNDEAEYVCIAENKAGEQDASIHLKVFAKPKITYVENQTAMELE 323
           H     +  L I NV  ND+AEY C    KAG +     L V   P+   V+ +T     
Sbjct: 443 HYIISGTYNLIIVNVTLNDQAEYTC----KAGSESYFGFLTVIDLPQNLTVQWETTPTPS 276

Query: 324 EQVTLTCEAS-GDPIPSITW 342
               L+C AS   P P ++W
Sbjct: 275 STSNLSCVASRAHPPPPLSW 216
>35419
          Length = 623

 Score = 35.0 bits (79), Expect = 0.093,   Method: Compositional matrix adjust.
 Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 4/97 (4%)
 Frame = -2

Query: 21  QVDIVPSQGEISVGESKFFLCQVAGDAKD---KDISWFSPNGEKLSPNQQRISVVWNDDD 77
           Q++  P   E++ G    F C    D ++     I W   N E +S  +QR++    D+ 
Sbjct: 571 QIEQAPMDLEVNAGTDAKFTCSGTTDPEEVHMLKIKWMKDNKE-ISTVEQRMTTNIQDN- 398

Query: 78  SSTLTIYNANIDDAGIYKCVVT-AEDGTQSEATVNVK 113
             +LTI    + D+G Y C+ T   D  ++ A + VK
Sbjct: 397 --SLTISGTIVRDSGTYTCISTNGLDSAEASAMLTVK 293

 Score = 33.9 bits (76), Expect = 0.23,   Method: Compositional matrix adjust.
 Identities = 27/113 (23%), Positives = 47/113 (41%), Gaps = 8/113 (7%)
 Frame = -2

Query: 317 QTAMELE----EQVTLTCEASGDP----IPSITWRTSTRNISSEEKTLDGHMVVRSHARV 368
           Q  M+LE         TC  + DP    +  I W    + IS+ E+ +       ++ + 
Sbjct: 562 QAPMDLEVNAGTDAKFTCSGTTDPEEVHMLKIKWMKDNKEISTVEQRM------TTNIQD 401

Query: 369 SSLTLKSIQYTDAGEYICTASNTIGQDSQSMYLEVQYAPKLQGPVAVYTWEGN 421
           +SLT+      D+G Y C ++N +     S  L V+  P +   V +   + N
Sbjct: 400 NSLTISGTIVRDSGTYTCISTNGLDSAEASAMLTVKDRPDVASEVKIEKCDDN 242
>29932
          Length = 748

 Score = 34.7 bits (78), Expect = 0.13,   Method: Compositional matrix adjust.
 Identities = 25/103 (24%), Positives = 44/103 (42%), Gaps = 1/103 (0%)
 Frame = +3

Query: 303 LKVFAKPKITYVEN-QTAMELEEQVTLTCEASGDPIPSITWRTSTRNISSEEKTLDGHMV 361
           L +   P+IT+  N    +E +  + + C+ +     ++ W T           +DG + 
Sbjct: 75  LVLLPLPQITFRPNIPLEVEADRNIEIYCDVTNARPENVQWATDNNRPLPGSVHIDGQI- 251

Query: 362 VRSHARVSSLTLKSIQYTDAGEYICTASNTIGQDSQSMYLEVQ 404
                    L   +I   DAG Y CTASN  G +S++  + V+
Sbjct: 252 ---------LRFVAITPADAGGYSCTASNKYGTNSKTAQVVVR 353
>22019
          Length = 314

 Score = 33.9 bits (76), Expect = 0.26,   Method: Composition-based stats.
 Identities = 18/50 (36%), Positives = 25/50 (50%)
 Frame = +3

Query: 359 HMVVRSHARVSSLTLKSIQYTDAGEYICTASNTIGQDSQSMYLEVQYAPK 408
           H    S   V +L L+ +   DAG Y+C  SN +GQ S  + L V   P+
Sbjct: 9   HSSRNSVGEVHTLLLQDVTNEDAGLYVCELSNMVGQASAVLQLLVTDRPQ 158
>12764
          Length = 1055

 Score = 33.9 bits (76), Expect = 0.27,   Method: Compositional matrix adjust.
 Identities = 22/66 (33%), Positives = 31/66 (46%), Gaps = 1/66 (1%)
 Frame = +1

Query: 328 LTCEASGDPIP-SITWRTSTRNISSEEKTLDGHMVVRSHARVSSLTLKSIQYTDAGEYIC 386
           LTC   G+P+P  + WR        E  TL         A  ++LTL ++  +D G Y C
Sbjct: 286 LTCITQGNPLPFLVEWRQE-----GENTTL---------ATGNTLTLTNLSLSDTGTYTC 423

Query: 387 TASNTI 392
           T  NT+
Sbjct: 424 TGYNTV 441

 Score = 29.6 bits (65), Expect = 4.5,   Method: Compositional matrix adjust.
 Identities = 18/70 (25%), Positives = 31/70 (44%), Gaps = 1/70 (1%)
 Frame = +1

Query: 123 APTPQEFKEGEDAVIVCDVVSS-LPPTIIWKHKGRDVILKKDVRFIVLSNNYLQIRGIKK 181
            P  Q+ +EG +  + C    + LP  + W+ +G +  L         + N L +  +  
Sbjct: 244 TPDTQQREEGLNLDLTCITQGNPLPFLVEWRQEGENTTLA--------TGNTLTLTNLSL 399

Query: 182 TDEGTYRCEG 191
           +D GTY C G
Sbjct: 400 SDTGTYTCTG 429
>17678
          Length = 876

 Score = 33.1 bits (74), Expect = 0.40,   Method: Composition-based stats.
 Identities = 14/32 (43%), Positives = 20/32 (62%)
 Frame = -3

Query: 370 SLTLKSIQYTDAGEYICTASNTIGQDSQSMYL 401
           SL +  +   D G Y C ASN +G+DS++M L
Sbjct: 859 SLIIMRVSELDFGSYTCEASNLLGKDSETMTL 764
>17530
          Length = 503

 Score = 32.7 bits (73), Expect = 0.50,   Method: Compositional matrix adjust.
 Identities = 31/120 (25%), Positives = 49/120 (40%), Gaps = 11/120 (9%)
 Frame = +2

Query: 228 GQSVTLVCDADGF-PEPTMSWTKXXXXXXXXXXXXXKHIFSDDSSELTIRN-----VDKN 281
           GQ V   C + G  P PT++WTK               +    +S  + RN     +D +
Sbjct: 107 GQRVRFTCSSSGGNPPPTITWTKNGVQLINGVQQIG--VGQTSTSGGSTRNTVSVVMDHS 280

Query: 282 D-EAEYVCIAENKAG---EQDASIHLKVFAKPKITYVE-NQTAMELEEQVTLTCEASGDP 336
           D +A Y C   N+        AS+ L V   P IT+   +   + L+    +TC+   +P
Sbjct: 281 DHQANYTCFVYNQVNINSSLTASVVLNVRYSPIITFEPFSPYIVRLDRPANITCQVDANP 460
>34811
          Length = 613

 Score = 32.0 bits (71), Expect = 0.90,   Method: Compositional matrix adjust.
 Identities = 34/147 (23%), Positives = 63/147 (42%), Gaps = 16/147 (10%)
 Frame = +1

Query: 371 LTLKSIQYTDAGEYICTASNTIG----QDSQSMY------LEVQYAPKLQGPVAVYTWE- 419
           L+   I+  DAG Y C AS+ +       +++++      + VQYAP   G  ++   + 
Sbjct: 73  LSFPQIRRADAGNYSCKASSLLKVPGVGSTETVFGQGFTTINVQYAP---GAASIDKIDN 243

Query: 420 ---GNQVNITCEVF--AYPSATISWFRDGQLLPSSNYSNIKIYNTPSASYLEVTPDSEND 474
              G ++ +TC      +P A   W R+G     ++           A+Y+ +   + +D
Sbjct: 244 IDVGQRLQLTCSAAPQGFPEARFKWHRNGAEQSQTD-----------ANYV-IXSTALSD 387

Query: 475 FGNYNCTAVNRIGQESLEFILVQADTP 501
              Y+CT  N  G+ +   I V  + P
Sbjct: 388 TAVYSCTPYNIAGEGAPANISVSINEP 468
>29881
          Length = 416

 Score = 31.6 bits (70), Expect = 1.3,   Method: Composition-based stats.
 Identities = 19/69 (27%), Positives = 30/69 (43%)
 Frame = -3

Query: 150 IWKHKGRDVILKKDVRFIVLSNNYLQIRGIKKTDEGTYRCEGRILARGEINFKDIQVIVN 209
           +W+  G   +  +  R  +L NNYL +  + +TD G Y C  R     E  F  +   +N
Sbjct: 354 MWRKDGD--MFTQGPRKRMLVNNYLMVSNVVETDAGQYTCAAR---NSEGCFAKVSAYLN 190

Query: 210 VPPTVQARQ 218
           V      R+
Sbjct: 189 VETVGHGRE 163
>25455
          Length = 444

 Score = 30.8 bits (68), Expect = 1.9,   Method: Compositional matrix adjust.
 Identities = 26/95 (27%), Positives = 44/95 (46%), Gaps = 6/95 (6%)
 Frame = +1

Query: 123 APTPQEFKEGEDAVIVCDVVSSLPPTIIWKHKGRDV--ILKKDVRF----IVLSNNYLQI 176
           AP   E + GE A I C+  +   P   W   GR++  +++ DVRF      L+++ L +
Sbjct: 94  APQVTEVEVGETAEITCNATAIPDPVTNWFVNGREISDVVEHDVRFQSGRFDLTSDRLIL 273

Query: 177 RGIKKTDEGTYRCEGRILARGEINFKDIQVIVNVP 211
           R +  T EG    +  +  R    + D+ + V  P
Sbjct: 274 RNV--TIEGRMVVQCNVTNRYGHLWADVSLNVLTP 372

 Score = 30.8 bits (68), Expect = 2.1,   Method: Compositional matrix adjust.
 Identities = 30/126 (23%), Positives = 47/126 (37%), Gaps = 6/126 (4%)
 Frame = +1

Query: 187 YRCEGRILARGEINF--KDIQVIVNVPPT-VQARQSIVNATANLGQSVTLVCDADGFPEP 243
           YRC         INF  ++++V+V   P+ V A Q        +G++  + C+A   P+P
Sbjct: 1   YRCWAESTVH-HINFPLREMRVVVQSAPSWVVAPQV---TEVEVGETAEITCNATAIPDP 168

Query: 244 TMSW---TKXXXXXXXXXXXXXKHIFSDDSSELTIRNVDKNDEAEYVCIAENKAGEQDAS 300
             +W    +                F   S  L +RNV         C   N+ G   A 
Sbjct: 169 VTNWFVNGREISDVVEHDVRFQSGRFDLTSDRLILRNVTIEGRMVVQCNVTNRYGHLWAD 348

Query: 301 IHLKVF 306
           + L V 
Sbjct: 349 VSLNVL 366
>37675
          Length = 741

 Score = 30.0 bits (66), Expect = 3.6,   Method: Compositional matrix adjust.
 Identities = 22/84 (26%), Positives = 36/84 (42%), Gaps = 1/84 (1%)
 Frame = +2

Query: 208 VNVPPTVQARQSIVNATANLGQSVTLVCDADGFPEPTMSWTKXXXXXXXXXXXXXKHIFS 267
           V +PP V+     +   A L  +  + C A+G P+PT+SW               +H   
Sbjct: 59  VQMPPVVKVSPHSLIYPARL--NAKMKCHAEGVPKPTISWL----FNNVPISEDPQHYDL 220

Query: 268 DDSSE-LTIRNVDKNDEAEYVCIA 290
           + ++E L + N    D   Y C+A
Sbjct: 221 ESANELLVVYNAGDQDTGAYKCVA 292
>07940
          Length = 1336

 Score = 28.9 bits (63), Expect = 8.2,   Method: Compositional matrix adjust.
 Identities = 14/33 (42%), Positives = 18/33 (54%)
 Frame = -3

Query: 371  LTLKSIQYTDAGEYICTASNTIGQDSQSMYLEV 403
            L + +I   DAG Y C  SN IG +  S +L V
Sbjct: 1331 LIISNITVEDAGWYTCVVSNAIGVEYGSAWLTV 1233
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|13386146|ref|NP_080938.1| phosphoribosyl
pyrophosphate synthetase 2 [Mus musculus]
         (318 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

21831                                                                  66   2e-11
11894                                                                  29   2.4  
07115                                                                  29   3.1  
>21831
          Length = 1374

 Score = 65.9 bits (159), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 30/53 (56%), Positives = 40/53 (75%)
 Frame = -1

Query: 264 AAFEAVVVTNTIPQEDKMKHCSKIQVIDISMILAEAIRRTHNGESVSYLFSHV 316
           + +  VVVTNT+P E K   C KI+ +DIS +LAEAIRR H+GES+SYLF ++
Sbjct: 819 SLYVQVVVTNTVPHEVKKMQCHKIKTVDISSLLAEAIRRIHHGESMSYLFRNI 661
>11894
          Length = 1336

 Score = 29.3 bits (64), Expect = 2.4,   Method: Compositional matrix adjust.
 Identities = 12/29 (41%), Positives = 18/29 (62%)
 Frame = +3

Query: 256 PAISRINSAAFEAVVVTNTIPQEDKMKHC 284
           P++ RI+  A  A  +T+T+P  D  KHC
Sbjct: 336 PSVIRIHVHAHCAHSLTHTLPHTDTRKHC 422
>07115
          Length = 1190

 Score = 28.9 bits (63), Expect = 3.1,   Method: Compositional matrix adjust.
 Identities = 13/35 (37%), Positives = 24/35 (68%)
 Frame = +1

Query: 99  KKDKSRAPISAKLVANMLSVAGADHIITMDLHASQ 133
           K++K++AP++AK     +++    +I +MDLH SQ
Sbjct: 313 KQNKNKAPMAAKR*EQPITLLIYTNIFSMDLHKSQ 417
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31324569|ref|NP_598855.2| neurocalcin delta [Mus
musculus]
         (193 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

26019                                                                  65   2e-11
14594                                                                  57   6e-09
18571                                                                  43   1e-04
00167                                                                  41   3e-04
07678                                                                  41   4e-04
05237                                                                  40   6e-04
01019                                                                  39   0.002
05230                                                                  35   0.014
22063                                                                  35   0.014
14945                                                                  35   0.015
38338                                                                  34   0.037
15966                                                                  34   0.046
07198                                                                  33   0.058
01773                                                                  33   0.070
33397                                                                  33   0.086
26849                                                                  32   0.12 
17484                                                                  32   0.19 
35074                                                                  32   0.21 
39823                                                                  31   0.27 
02929                                                                  28   1.7  
32088                                                                  28   2.2  
14366                                                                  27   4.2  
08380                                                                  26   8.3  
>26019
          Length = 1561

 Score = 65.1 bits (157), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 33/90 (36%), Positives = 55/90 (61%), Gaps = 1/90 (1%)
 Frame = +2

Query: 40  SGHLSMEEFKKIYGNFFPYGDASKFAEHVFRTFDANGDGTIDFREFIIALSVTS-RGKLE 98
           SG LS++EF  +     P    +   + V   FD +G+G +DF+EFI  +S  S +G  E
Sbjct: 140 SGSLSIDEFMSL-----PELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGISQFSVKGDKE 304

Query: 99  QKLKWAFSMYDLDGNGYISKAEMLEIVQAI 128
            KL++AF +YD+D +GYIS  E+ ++++ +
Sbjct: 305 SKLRFAFKIYDMDKDGYISNGELFQVLKMM 394
>14594
          Length = 1014

 Score = 56.6 bits (135), Expect = 6e-09,   Method: Compositional matrix adjust.
 Identities = 31/99 (31%), Positives = 57/99 (57%), Gaps = 1/99 (1%)
 Frame = +3

Query: 73  DANGDGTIDFREFIIALSVTSRGK-LEQKLKWAFSMYDLDGNGYISKAEMLEIVQAIYKM 131
           DA+G+GTIDF EF+  ++   +    E++L+ AF ++D DGNGYIS AE+  ++  +   
Sbjct: 579 DADGNGTIDFEEFLHMMARKMKDTDCEEELREAFRVFDKDGNGYISAAELRHVMTNL--- 749

Query: 132 VSSVMKMPEDESTPEKRTEKIFRQMDTNRDGKLSLEEFI 170
                     E   ++  +++ ++ D + DG ++ EEF+
Sbjct: 750 ---------GEKLTDEEVDEMIKEADLDGDGMVNYEEFV 839

 Score = 34.7 bits (78), Expect = 0.025,   Method: Compositional matrix adjust.
 Identities = 25/105 (23%), Positives = 46/105 (43%)
 Frame = +3

Query: 23  TEHEIQEWYKGFLRDCPSGHLSMEEFKKIYGNFFPYGDASKFAEHVFRTFDANGDGTIDF 82
           TE+E+Q+       D  +G +  EEF  +        D  +     FR FD +G+G I  
Sbjct: 543 TENELQDMINEVDAD-GNGTIDFEEFLHMMARKMKDTDCEEELREAFRVFDKDGNGYISA 719

Query: 83  REFIIALSVTSRGKLEQKLKWAFSMYDLDGNGYISKAEMLEIVQA 127
            E    ++       ++++       DLDG+G ++  E + ++ A
Sbjct: 720 AELRHVMTNLGEKLTDEEVDEMIKEADLDGDGMVNYEEFVTMMTA 854

 Score = 32.3 bits (72), Expect = 0.12,   Method: Compositional matrix adjust.
 Identities = 16/72 (22%), Positives = 38/72 (52%)
 Frame = +3

Query: 100 KLKWAFSMYDLDGNGYISKAEMLEIVQAIYKMVSSVMKMPEDESTPEKRTEKIFRQMDTN 159
           + K AFS++D DG+G I+ +E+  +++++             ++  E   + +  ++D +
Sbjct: 444 EFKEAFSLFDKDGDGTITTSELGTVMRSL------------GQNPTENELQDMINEVDAD 587

Query: 160 RDGKLSLEEFIR 171
            +G +  EEF+ 
Sbjct: 588 GNGTIDFEEFLH 623
>18571
          Length = 821

 Score = 42.7 bits (99), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 21/38 (55%), Positives = 23/38 (60%)
 Frame = -2

Query: 153 FRQMDTNRDGKLSLEEFIRGAKSDPSIVRLLQCDPSSA 190
           FRQMD N DGKLSLEEFI G  + P +       PS A
Sbjct: 811 FRQMDKNLDGKLSLEEFIEGP*TIPPLFDFCSVTPSRA 698
>00167
          Length = 2176

 Score = 40.8 bits (94), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 21/56 (37%), Positives = 33/56 (58%)
 Frame = +3

Query: 67  HVFRTFDANGDGTIDFREFIIALSVTSRGKLEQKLKWAFSMYDLDGNGYISKAEML 122
            VFR FD +G GT+DF EF++AL         + +K AF+  D  G+G I+  +++
Sbjct: 852 EVFRRFDKDGTGTLDFEEFLLALRPKMNEFRRKLVKKAFAKMDKTGDGIITADDLV 1019

 Score = 31.6 bits (70), Expect = 0.20,   Method: Compositional matrix adjust.
 Identities = 14/22 (63%), Positives = 17/22 (77%)
 Frame = +3

Query: 153 FRQMDTNRDGKLSLEEFIRGAK 174
           FR MD NRD KLS++EFI G +
Sbjct: 747 FRIMDDNRDRKLSVDEFIVGCR 812
>07678
          Length = 958

 Score = 40.8 bits (94), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 36/129 (27%), Positives = 59/129 (45%), Gaps = 2/129 (1%)
 Frame = +1

Query: 43  LSMEEFKKIYGNFFPYGDASKFAEHVFRTFDANGDGTIDFREFIIALSVTSRGKLEQKLK 102
           L  +EFKK    F          + +F  FD +  GTIDF EF++ L        +  ++
Sbjct: 370 LDFKEFKKGITEFGLTQFEGDVIQEMFTCFDKDZSGTIDFDEFLVKLRPPMSQMRKDLIQ 549

Query: 103 WAFSMYDLDGNGYISKAEMLEIVQAIYKMVSSVMKMPEDESTPEKRTEKIFRQMDT--NR 160
            AF   D  G+G ++    +E ++ +Y  V+   K    E T E+         D+  ++
Sbjct: 550 RAFQKLDKTGDGVVT----VEDLKGVYN-VTKHPKYLNGEWTEERILRIFLDSFDSPNDK 714

Query: 161 DGKLSLEEF 169
           DGK++ EEF
Sbjct: 715 DGKITKEEF 741

 Score = 27.7 bits (60), Expect = 2.8,   Method: Compositional matrix adjust.
 Identities = 23/102 (22%), Positives = 50/102 (49%), Gaps = 1/102 (0%)
 Frame = +1

Query: 69  FRTFDANGDGTIDFREFIIALSVTSRGKLE-QKLKWAFSMYDLDGNGYISKAEMLEIVQA 127
           F+  D +G+ ++DF+EF   ++     + E   ++  F+ +D D +G I   E L     
Sbjct: 337 FKIMDDDGNRSLDFKEFKKGITEFGLTQFEGDVIQEMFTCFDKDZSGTIDFDEFL----- 501

Query: 128 IYKMVSSVMKMPEDESTPEKRTEKIFRQMDTNRDGKLSLEEF 169
             K+   + +M +D        ++ F+++D   DG +++E+ 
Sbjct: 502 -VKLRPPMSQMRKD------LIQRAFQKLDKTGDGVVTVEDL 606
>05237
          Length = 472

 Score = 40.0 bits (92), Expect = 6e-04,   Method: Compositional matrix adjust.
 Identities = 19/74 (25%), Positives = 42/74 (56%)
 Frame = +3

Query: 98  EQKLKWAFSMYDLDGNGYISKAEMLEIVQAIYKMVSSVMKMPEDESTPEKRTEKIFRQMD 157
           + +L+ AF ++D DGNG+IS +E+  ++  +             E   ++  +++ R+ D
Sbjct: 24  DDELREAFRVFDKDGNGFISASELRHVMTNLG------------EKLTDEEVDEMIREAD 167

Query: 158 TNRDGKLSLEEFIR 171
            + DG+++ EEF++
Sbjct: 168 IDGDGQVNYEEFVK 209

 Score = 28.1 bits (61), Expect = 2.2,   Method: Compositional matrix adjust.
 Identities = 17/64 (26%), Positives = 34/64 (53%)
 Frame = +3

Query: 23 TEHEIQEWYKGFLRDCPSGHLSMEEFKKIYGNFFPYGDASKFAEHVFRTFDANGDGTIDF 82
          T+ E++E ++ F +D  +G +S  E + +  N        +  E + R  D +GDG +++
Sbjct: 21 TDDELREAFRVFDKD-GNGFISASELRHVMTNLGEKLTDEEVDEMI-READIDGDGQVNY 194

Query: 83 REFI 86
           EF+
Sbjct: 195EEFV 206
>01019
          Length = 1705

 Score = 38.5 bits (88), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 18/69 (26%), Positives = 37/69 (53%)
 Frame = +1

Query: 102 KWAFSMYDLDGNGYISKAEMLEIVQAIYKMVSSVMKMPEDESTPEKRTEKIFRQMDTNRD 161
           +W   ++D DGNG+IS AE+  ++  +             E   ++  +++ R+ D + D
Sbjct: 28  EWPLLVFDKDGNGFISAAELRHVMTNL------------GEKLTDEEVDEMIREADIDGD 171

Query: 162 GKLSLEEFI 170
           G+++ EEF+
Sbjct: 172 GQVNYEEFV 198
>05230
          Length = 843

 Score = 35.4 bits (80), Expect = 0.014,   Method: Compositional matrix adjust.
 Identities = 23/82 (28%), Positives = 45/82 (54%)
 Frame = -2

Query: 90  SVTSRGKLEQKLKWAFSMYDLDGNGYISKAEMLEIVQAIYKMVSSVMKMPEDESTPEKRT 149
           SV  +  + +KL   F+ +D DG+G+ S+ +++E ++ I   +           TP+ R 
Sbjct: 659 SVDMKTNMWRKL---FAQFDTDGSGWASREDVIEGLENIGITI-----------TPDLRA 522

Query: 150 EKIFRQMDTNRDGKLSLEEFIR 171
           +   + MD N+DGK++  +F+R
Sbjct: 521 K--IKAMDGNKDGKINYADFLR 462
>22063
          Length = 688

 Score = 35.4 bits (80), Expect = 0.014,   Method: Compositional matrix adjust.
 Identities = 28/96 (29%), Positives = 43/96 (44%)
 Frame = +3

Query: 68  VFRTFDANGDGTIDFREFIIALSVTSRGKLEQKLKWAFSMYDLDGNGYISKAEMLEIVQA 127
            F  FDA+G GTID +E  +A+        ++++K   +  D +G G I   + L I+  
Sbjct: 186 AFDLFDADGSGTIDAKELKVAMRALGFEPKKEEIKKMIAEIDKEGTGTIDFNDFLTIM-- 359

Query: 128 IYKMVSSVMKMPEDESTPEKRTEKIFRQMDTNRDGK 163
                    KM E ++  E    K FR  D +  GK
Sbjct: 360 -------TQKMSEKDAKEE--ILKAFRLFDDDETGK 440
>14945
          Length = 1337

 Score = 35.4 bits (80), Expect = 0.015,   Method: Compositional matrix adjust.
 Identities = 30/109 (27%), Positives = 47/109 (43%)
 Frame = +1

Query: 67  HVFRTFDANGDGTIDFREFIIALSVTSRGKLEQKLKWAFSMYDLDGNGYISKAEMLEIVQ 126
             F  FDA+G GTID +E  +A+        ++++K   +  D +G G I   + L I+ 
Sbjct: 124 EAFDLFDADGSGTIDAKELKVAMRALGFEPKKEEIKKMIAEIDKEGTGTIDFNDFLTIM- 300

Query: 127 AIYKMVSSVMKMPEDESTPEKRTEKIFRQMDTNRDGKLSLEEFIRGAKS 175
                     KM E ++  E    K FR  D +  GK  L +   G + 
Sbjct: 301 --------TQKMSEKDAKEE--ILKAFRLFDDDETGKNLLPQLETGGQG 417
>38338
          Length = 463

 Score = 33.9 bits (76), Expect = 0.037,   Method: Compositional matrix adjust.
 Identities = 17/49 (34%), Positives = 24/49 (48%)
 Frame = -2

Query: 68  VFRTFDANGDGTIDFREFIIALSVTSRGKLEQKLKWAFSMYDLDGNGYI 116
            F  FD +GDGTI  +E    +    +   E +L+   +  D DGNG I
Sbjct: 153 AFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTI 7

 Score = 27.3 bits (59), Expect = 3.7,   Method: Compositional matrix adjust.
 Identities = 10/29 (34%), Positives = 21/29 (72%)
 Frame = -2

Query: 100 KLKWAFSMYDLDGNGYISKAEMLEIVQAI 128
           + K AFS++D DG+G I+  E+  +++++
Sbjct: 165 EFKEAFSLFDKDGDGTITTKELGTVMRSL 79
>15966
          Length = 362

 Score = 33.9 bits (76), Expect = 0.046,   Method: Compositional matrix adjust.
 Identities = 31/112 (27%), Positives = 45/112 (40%), Gaps = 1/112 (0%)
 Frame = +2

Query: 60  DASKFAEHV-FRTFDANGDGTIDFREFIIALSVTSRGKLEQKLKWAFSMYDLDGNGYISK 118
           D S+ + H  F    + GD  I F EF   L         QKL   F   D  G+GY+ +
Sbjct: 20  DESRRSRHARFFVVPSCGDKRITFEEFCKGLDQIVM--FVQKLAELFKAKDKSGDGYLDR 193

Query: 119 AEMLEIVQAIYKMVSSVMKMPEDESTPEKRTEKIFRQMDTNRDGKLSLEEFI 170
            E+  ++        S  K   D+ +       I +  D N D K+  EEF+
Sbjct: 194 DELKALLD------ESGQKFTADDVSA------ILKSADKNNDNKICFEEFV 313
>07198
          Length = 1675

 Score = 33.5 bits (75), Expect = 0.058,   Method: Compositional matrix adjust.
 Identities = 33/103 (32%), Positives = 48/103 (46%), Gaps = 2/103 (1%)
 Frame = -3

Query: 68  VFRTFDANGDGTIDFREFIIALSVTSRGKLEQKLKWAFSMYDLDGNGYISKAEMLEIVQA 127
           VF   DAN DG+++ +E+       S  +LE  L+      D + +G IS  E       
Sbjct: 467 VFDAADANKDGSLNSKEYFAFFMPNSFPQLE--LERFMRQSDKNKDGTISMEEF------ 312

Query: 128 IYKMVSSVMKMPEDESTPEKRT--EKIFRQMDTNRDGKLSLEE 168
                     MPE  +T + RT  E+ F+  D ++DG LSLEE
Sbjct: 311 ----------MPEG-ATGDTRTSSEESFKNYDKDKDGSLSLEE 216

 Score = 32.7 bits (73), Expect = 0.086,   Method: Compositional matrix adjust.
 Identities = 36/138 (26%), Positives = 58/138 (42%), Gaps = 2/138 (1%)
 Frame = -3

Query: 41  GHLSMEEF-KKIYGNFFPYGDASKFAEHVFRTFDANGDGTIDFREFIIALSVTSRGKLEQ 99
           G ++ +E+  K+YG  F   D  +  + V    D N D   +F+E +  L +    +   
Sbjct: 626 GKVTWDEYLDKVYG--FNKLDVDEMQKSVNEAKDKNTD---EFKENVNNLELVDEDRK-- 468

Query: 100 KLKWAFSMYDLDGNGYISKAEMLEIVQAIYKMVSSVMKMPEDESTPEKRTEKIFRQMDTN 159
                F   D + +G ++  E                 MP   S P+   E+  RQ D N
Sbjct: 467 ----VFDAADANKDGSLNSKEYFAFF------------MPN--SFPQLELERFMRQSDKN 342

Query: 160 RDGKLSLEEFI-RGAKSD 176
           +DG +S+EEF+  GA  D
Sbjct: 341 KDGTISMEEFMPEGATGD 288
>01773
          Length = 1950

 Score = 33.1 bits (74), Expect = 0.070,   Method: Compositional matrix adjust.
 Identities = 34/131 (25%), Positives = 54/131 (41%), Gaps = 1/131 (0%)
 Frame = +1

Query: 41  GHLSMEEFKKIYGNFFPYGDASKFAEHVFRTFDA-NGDGTIDFREFIIALSVTSRGKLEQ 99
           G+L ++E ++++         S+ A+  F  FD   GD  I F  F   L         Q
Sbjct: 199 GYLEIKELRELFKRNGSSLSDSQIAD-TFVFFDGPRGDKRITFEXFCKGLDQIVM--FVQ 369

Query: 100 KLKWAFSMYDLDGNGYISKAEMLEIVQAIYKMVSSVMKMPEDESTPEKRTEKIFRQMDTN 159
           KL   F   D  G+GY+ + E+  ++        S  K   D+ +       I +  D N
Sbjct: 370 KLAELFKAKDKSGDGYLDRDELKALLD------ESGQKFTADDVSA------ILKSADKN 513

Query: 160 RDGKLSLEEFI 170
            D K+  EEF+
Sbjct: 514 NDNKICFEEFV 546
>33397
          Length = 1723

 Score = 32.7 bits (73), Expect = 0.086,   Method: Compositional matrix adjust.
 Identities = 16/29 (55%), Positives = 18/29 (62%)
 Frame = +3

Query: 143 STPEKRTEKIFRQMDTNRDGKLSLEEFIR 171
           STP +  E  FR  D N DG+L LEEF R
Sbjct: 180 STPPRNFEIAFRMFDINGDGELDLEEFNR 266

 Score = 27.7 bits (60), Expect = 2.7,   Method: Compositional matrix adjust.
 Identities = 18/67 (26%), Positives = 32/67 (47%)
 Frame = +3

Query: 78  GTIDFREFIIALSVTSRGKLEQKLKWAFSMYDLDGNGYISKAEMLEIVQAIYKMVSSVMK 137
           G I F ++I  L+V S     +  + AF M+D++G+G +   E    VQ + +  + V  
Sbjct: 135 GLISFSDYIFLLTVLSTPP--RNFEIAFRMFDINGDGELD-LEEFNRVQGVIRNQTHVGA 305

Query: 138 MPEDEST 144
              D + 
Sbjct: 306 RHRDHAV 326
>26849
          Length = 649

 Score = 32.3 bits (72), Expect = 0.12,   Method: Compositional matrix adjust.
 Identities = 20/52 (38%), Positives = 31/52 (59%), Gaps = 1/52 (1%)
 Frame = +2

Query: 43  LSMEEFKK-IYGNFFPYGDASKFAEHVFRTFDANGDGTIDFREFIIALSVTS 93
           LS+EEFKK I        +A    E +F  FD +G+GTI+  EF++ ++ T+
Sbjct: 218 LSLEEFKKGILDMHIDINEAD--IEDMFYRFDNDGNGTINMTEFLLKVASTN 367
>17484
          Length = 471

 Score = 31.6 bits (70), Expect = 0.19,   Method: Compositional matrix adjust.
 Identities = 21/65 (32%), Positives = 30/65 (46%), Gaps = 5/65 (7%)
 Frame = -3

Query: 68  VFRTFDANGDGTIDFREFIIALSVTSRGKLEQKLKWA-----FSMYDLDGNGYISKAEML 122
            FR FD NGDG I   E   A++     K+ QKL  A         D DG+G+++  E  
Sbjct: 256 AFRAFDQNGDGVISISELRQAMA-----KMGQKLSDADVESIIRDVDKDGDGFVNYEEFT 92

Query: 123 EIVQA 127
           + +  
Sbjct: 91  KFIAG 77

 Score = 27.7 bits (60), Expect = 3.1,   Method: Compositional matrix adjust.
 Identities = 17/59 (28%), Positives = 27/59 (45%)
 Frame = -1

Query: 108 YDLDGNGYISKAEMLEIVQAIYKMVSSVMKMPEDESTPEKRTEKIFRQMDTNRDGKLSL 166
           YD DGNG I++ E   +V+ +              S  EK  E++ +  DT+  G + L
Sbjct: 465 YDQDGNGKITRNEFRSVVRML------------GHSLSEKELEEMMQAADTDASGAIEL 325
>35074
          Length = 654

 Score = 31.6 bits (70), Expect = 0.21,   Method: Compositional matrix adjust.
 Identities = 14/35 (40%), Positives = 22/35 (62%)
 Frame = +2

Query: 148 RTEKIFRQMDTNRDGKLSLEEFIRGAKSDPSIVRL 182
           R++ I   M  N+ G + L  FIR A++DP++V L
Sbjct: 62  RSQNIPASMVNNQFGMVGLLTFIRAAETDPNLVTL 166
>39823
          Length = 655

 Score = 31.2 bits (69), Expect = 0.27,   Method: Compositional matrix adjust.
 Identities = 35/138 (25%), Positives = 59/138 (42%), Gaps = 13/138 (9%)
 Frame = +3

Query: 67  HVFRTFDANGDGTIDFREFIIALSVTSRGKL------------EQKLKWAFSMYDLDGNG 114
            VF  FD + D  + + E+  A S+TS+  L            E+ ++  F M D D + 
Sbjct: 69  QVFDEFDKDRDNQVTWEEYRDARSLTSKDPLARGQGRRMSEMTERVVRLEFQMADQDEDQ 248

Query: 115 YISKAEMLEIVQAIYKMVSSVMKMPEDESTPEK-RTEKIFRQMDTNRDGKLSLEEFIRGA 173
            +   E L +         S  ++ +  S  E  R + +F+ +DT+RDG ++  E  R  
Sbjct: 249 VLDWWEFLNLAAQHLLGRRSETELVDLLSEKEVVRLKVVFQGLDTDRDGVVTGLEVRRAV 428

Query: 174 KSDPSIVRLLQCDPSSAG 191
           ++  S        P SAG
Sbjct: 429 RAWVS--------PLSAG 458
>02929
          Length = 1353

 Score = 28.5 bits (62), Expect = 1.7,   Method: Compositional matrix adjust.
 Identities = 23/97 (23%), Positives = 43/97 (44%), Gaps = 1/97 (1%)
 Frame = +2

Query: 47  EFKKIYGNFFPYGDASKF-AEHVFRTFDANGDGTIDFREFIIALSVTSRGKLEQKLKWAF 105
           +F+   G +  +  A KF     FR  D +GDG +   EF+  +  +       +L   F
Sbjct: 125 DFESWRGKYLKWIQAKKFRVTDFFRRQDKDGDGFLTEEEFVNGMMQSRFPTNRTELNAVF 304

Query: 106 SMYDLDGNGYISKAEMLEIVQAIYKMVSSVMKMPEDE 142
            ++D +  G I   + ++ ++   K  +S   M +DE
Sbjct: 305 DIFDREKRGLIEYKDFVDALKPD-KFRTSSRAMSDDE 412
>32088
          Length = 1928

 Score = 28.1 bits (61), Expect = 2.2,   Method: Compositional matrix adjust.
 Identities = 18/70 (25%), Positives = 31/70 (44%)
 Frame = +1

Query: 100  KLKWAFSMYDLDGNGYISKAEMLEIVQAIYKMVSSVMKMPEDESTPEKRTEKIFRQMDTN 159
            +L+  F   D D NG+IS  E+    +A+   +            P      I  + D +
Sbjct: 946  ELRSVFDSIDDDNNGHISXGELDSAFRAVGLNI------------PGYELRTIMSKYDAS 1089

Query: 160  RDGKLSLEEF 169
             DG+L+++EF
Sbjct: 1090 GDGRLNMDEF 1119
>14366
          Length = 499

 Score = 27.3 bits (59), Expect = 4.2,   Method: Compositional matrix adjust.
 Identities = 17/84 (20%), Positives = 38/84 (45%)
 Frame = -3

Query: 43  LSMEEFKKIYGNFFPYGDASKFAEHVFRTFDANGDGTIDFREFIIALSVTSRGKLEQKLK 102
           L+++E   I   +    + S      FR FD  G+G I+  E    L+       ++++ 
Sbjct: 311 LTLQEVIAIVTKYEFAPETSDNLREAFRIFDKEGNGMINAAELRHVLTHLGEKLSDEEVD 132

Query: 103 WAFSMYDLDGNGYISKAEMLEIVQ 126
                 D+ G+G +S  + +++++
Sbjct: 131 EMIREADISGDGQVSYNDFVKVME 60
>08380
          Length = 1236

 Score = 26.2 bits (56), Expect = 8.3,   Method: Compositional matrix adjust.
 Identities = 28/136 (20%), Positives = 55/136 (40%), Gaps = 24/136 (17%)
 Frame = -1

Query: 58  YGDASKFAEHVFRTFDANGDGTIDFREFIIAL--------SVTSRGKL------------ 97
           + +A++  E +F+  D + +G + ++E+ +           V SR  +            
Sbjct: 783 FSEATQENEEIFKHLDPDNNGKVHWKEYYVHFLLAKGYKQDVASRHVVDYDZIQLDPDAK 604

Query: 98  EQKLKWAFSMYDLDG---NGYISKAEMLEIVQAIYKMVSSVMKMPED-ESTPEKRTEKIF 153
           E+ +++ F   D DG   +  +++ E +              + PE  E T       I 
Sbjct: 603 EEIIRYKFRWSDADGEPMDNELTREEFMSF------------RHPEQSEKTLNNMVNGIL 460

Query: 154 RQMDTNRDGKLSLEEF 169
             +DTN DG ++ EEF
Sbjct: 459 GGIDTNGDGVVTEEEF 412
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31542139|ref|NP_665703.2| ADP-ribosylation factor
GTPase activating protein 1 [Mus musculus]
         (414 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

02351                                                                  66   2e-11
02435                                                                  36   0.027
31279                                                                  30   2.4  
30691                                                                  29   4.0  
>02351
          Length = 939

 Score = 66.2 bits (160), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 26/68 (38%), Positives = 39/68 (57%)
 Frame = +3

Query: 13 VRAQDENNVCFECGAFNPQWVSVTYGIWICLECSGRHRGLGVHLSFVRSVTMDKWKDIEL 72
          +R    N +C +CG  +P W S+  G  +C+EC G HR +G H+S VRS+ +D W     
Sbjct: 6  IRTTRGNTICVDCGTPSPSWASINLGAVMCIECCGVHRNIGTHISRVRSLDLDDWPPEVT 185

Query: 73 EKMKAGGN 80
          + M + GN
Sbjct: 186KVMTSIGN 209
>02435
          Length = 1890

 Score = 36.2 bits (82), Expect = 0.027,   Method: Compositional matrix adjust.
 Identities = 25/92 (27%), Positives = 43/92 (46%), Gaps = 4/92 (4%)
 Frame = +2

Query: 33  VSVTYGIWICL----ECSGRHRGLGVHLSFVRSVTMDKWKDIELEKMKAGGNAKFREFLE 88
           +++ Y I +C     +CS       +H+          W  ++L  M+ GGN+  R F  
Sbjct: 407 IALKYHIILCTS*STQCS-------LHVGHQL*SKQ*HWSWLQLRAMQIGGNSNARIFFN 565

Query: 89  TQDDYEPSWSLQDKYSSRAAALFRDKVATLAE 120
                  +   Q KY+SRAA ++RDK+ + A+
Sbjct: 566 EHGCT--TTDAQQKYNSRAARMYRDKLLSQAQ 655
>31279
          Length = 568

 Score = 29.6 bits (65), Expect = 2.4,   Method: Compositional matrix adjust.
 Identities = 11/24 (45%), Positives = 14/24 (58%)
 Frame = +3

Query: 11  KEVRAQDENNVCFECGAFNPQWVS 34
           K +     N  CF+C  F+PQWVS
Sbjct: 237 KAICYLSINLYCFDCIVFSPQWVS 308
>30691
          Length = 681

 Score = 28.9 bits (63), Expect = 4.0,   Method: Compositional matrix adjust.
 Identities = 12/29 (41%), Positives = 20/29 (68%)
 Frame = -1

Query: 30  PQWVSVTYGIWICLECSGRHRGLGVHLSF 58
           P++ S T  +WIC++ S R++ + VH SF
Sbjct: 159 PRYPSTTVLLWICID*SWRYKNVSVHGSF 73
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|37674240|ref|NP_780485.2| formin homology 2 domain
containing 3 [Mus musculus]
         (1578 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

11636                                                                  69   2e-11
06817                                                                  55   2e-07
06790                                                                  49   2e-05
27291                                                                  47   7e-05
35444                                                                  39   0.014
>11636
          Length = 819

 Score = 68.9 bits (167), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 48/183 (26%), Positives = 96/183 (52%), Gaps = 6/183 (3%)
 Frame = +1

Query: 1150 LNKEGIEKILTMIPTEEEKQKIQE--AQLANPEVPLGSAEQFLLTLSSISELSARLHLWA 1207
            L K+ +E++L  +PT+EE   + E  A++ N    +  A++FL  +S I+    RL    
Sbjct: 7    LPKDMVEQLLKFVPTQEESSLLSEYAAEIDN----MARADRFLFEMSKITHYEERLKALY 174

Query: 1208 FKMDYETTEKEVAEPLLDLKEGIDQLENNKTLGFILSTLLAIGNFLNGT---NAKAFELS 1264
            FK  ++    +  + +  + E   ++  ++ L  +L  +LA GN++N     NA  F+ +
Sbjct: 175  FKKKFQERRHDCKQKIEAVHEACKEVFRSRKLKQLLELVLACGNYMNRGQRGNALGFKPT 354

Query: 1265 YLEKVPEVKDTVHKQ-SLLHHVCTMVVENFPDSSDLYSEIGAITRSAKVDFDQLQDNLCQ 1323
             L K+ + + +V KQ +LLH+V   + + F D   L  ++  +  +AKV+F  L+  +  
Sbjct: 355  SLNKMLDTRSSVSKQVTLLHYVVETLEKKFADVMKLEDDLPHVREAAKVNFKDLEKEIXA 534

Query: 1324 MER 1326
            +++
Sbjct: 535  LKK 543
>06817
          Length = 2234

 Score = 55.1 bits (131), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 41/190 (21%), Positives = 95/190 (50%), Gaps = 4/190 (2%)
 Frame = +1

Query: 1141 AILNFDEYALNKEGIEKILTMIPTEEEKQKIQEAQL-ANPEVPLGSAEQFLLTLSSISEL 1199
            AI   D   L+ + ++ + T++P E+E +  +  +    P   LG  ++F+L +  +  L
Sbjct: 37   AINGLDLKQLSLDLVDILQTILPNEQETKAFKMYERDRRPLEALGDEDKFMLHMVKVERL 216

Query: 1200 SARLHLWAFKMDYETTEKEVAEPLLDLKEGIDQLENNKTLGFILSTLLAIGNFLNGTNAK 1259
            S +L + +F  +Y     ++   +  +      L+N++ +  ++  +LA+GN++N     
Sbjct: 217  SHKLTIMSFIGNYYDNLHQLQPQVNAIIAASMSLKNSQKVKKLMEIILAMGNYMNSNKRG 396

Query: 1260 A---FELSYLEKVPEVKDTVHKQSLLHHVCTMVVENFPDSSDLYSEIGAITRSAKVDFDQ 1316
            A   F+L  L+ + + K    K +L+H +   V + FP+     SE+  + ++A V  + 
Sbjct: 397  AVYGFKLQSLDMLVDTKSGDRKTTLMHFLVQTVHDKFPELLTFDSELRFLDKAALVSMEN 576

Query: 1317 LQDNLCQMER 1326
            +  ++ ++E+
Sbjct: 577  ITTDVHELEK 606
>06790
          Length = 620

 Score = 48.9 bits (115), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 35/159 (22%), Positives = 77/159 (48%), Gaps = 4/159 (2%)
 Frame = -3

Query: 1141 AILNFDEYALNKEGIEKILTMIPTEEEKQKIQEAQL-ANPEVPLGSAEQFLLTLSSISEL 1199
            AI   D   L+ + ++ + T++P ++E +  +  +    P   LG  ++F++ +  +  L
Sbjct: 492  AINGLDLKRLSLDIVDILQTVLPNDQETKAFRLYERDRRPVESLGDEDKFMIQMVKVERL 313

Query: 1200 SARLHLWAFKMDYETTEKEVAEPLLDLKEGIDQLENNKTLGFILSTLLAIGNFLNGTN-- 1257
            S +L + +F  +Y      +   +  +      L+N+  +  ++  +LA+GN++N     
Sbjct: 312  SHKLTIMSFIGNYHDNLHHLQPQINAIIAASMSLKNSHKVKKMMEIILALGNYMNSNKRG 133

Query: 1258 -AKAFELSYLEKVPEVKDTVHKQSLLHHVCTMVVENFPD 1295
             A  F+L  L+ + + K    K +L+H +   V + FPD
Sbjct: 132  AAYGFKLQSLDMLVDTKSGDKKTTLMHFLVQTVQDKFPD 16
>27291
          Length = 435

 Score = 46.6 bits (109), Expect = 7e-05,   Method: Compositional matrix adjust.
 Identities = 29/117 (24%), Positives = 58/117 (49%), Gaps = 4/117 (3%)
 Frame = -2

Query: 1183 LGSAEQFLLTLSSISELSARLHLWAFKMDYETTEKEVAEPLLDLKEGIDQLENNKTLGFI 1242
            L   EQF + +SSI ++  RL    F+M ++    ++   L+   E  +++  ++    +
Sbjct: 383  LAEPEQFAIVMSSIKKVHQRLESMLFQMRFQEMVDDIKPDLVSATEACEEVMKSERFKQL 204

Query: 1243 LSTLLAIGNFLNGTNAKA----FELSYLEKVPEVKDTVHKQSLLHHVCTMVVENFPD 1295
            L  +L +GN+LN  +  A    F++S+L K+   K      ++LH +  ++    PD
Sbjct: 203  LELVLLMGNYLNSGSRNAQSIGFDISFLPKLENTKSQDGSITMLHFLAQVIESKHPD 33
>35444
          Length = 506

 Score = 39.3 bits (90), Expect = 0.014,   Method: Composition-based stats.
 Identities = 19/57 (33%), Positives = 31/57 (54%), Gaps = 3/57 (5%)
 Frame = -1

Query: 1242 ILSTLLAIGNFLNGTN---AKAFELSYLEKVPEVKDTVHKQSLLHHVCTMVVENFPD 1295
            +L  +LA GN+LN      A  F+L  L+ + + K T  + SLLH++   +   FP+
Sbjct: 398  VLEIVLAFGNYLNSNKRGPAYGFKLQSLDTLIDTKSTDKRSSLLHYIVATIRAKFPE 228
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|7949055|ref|NP_057886.1| hippocalcin-like 1 [Mus
musculus]
         (193 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

26019                                                                  65   2e-11
14594                                                                  54   5e-08
05237                                                                  44   3e-05
18571                                                                  43   9e-05
07198                                                                  40   6e-04
07678                                                                  40   6e-04
01019                                                                  39   0.001
00167                                                                  39   0.001
14366                                                                  37   0.007
15966                                                                  36   0.008
01773                                                                  35   0.019
38338                                                                  32   0.20 
33397                                                                  32   0.24 
08380                                                                  30   0.77 
01401                                                                  29   1.5  
17484                                                                  28   1.6  
32088                                                                  28   2.1  
07385                                                                  27   3.8  
26849                                                                  27   4.2  
28870                                                                  27   5.5  
22273                                                                  27   5.9  
>26019
          Length = 1561

 Score = 64.7 bits (156), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 32/90 (35%), Positives = 55/90 (61%), Gaps = 1/90 (1%)
 Frame = +2

Query: 40  TGHLTVDEFKKIYANFFPYGDASKFAEHVFRTFDTNSDGTIDFREFIIALSVTS-RGKLE 98
           +G L++DEF  +     P    +   + V   FDT+ +G +DF+EFI  +S  S +G  E
Sbjct: 140 SGSLSIDEFMSL-----PELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGISQFSVKGDKE 304

Query: 99  QKLKWAFSMYDLDGNGYISRSEMLEIVQAI 128
            KL++AF +YD+D +GYIS  E+ ++++ +
Sbjct: 305 SKLRFAFKIYDMDKDGYISNGELFQVLKMM 394
>14594
          Length = 1014

 Score = 53.5 bits (127), Expect = 5e-08,   Method: Compositional matrix adjust.
 Identities = 29/99 (29%), Positives = 55/99 (55%), Gaps = 1/99 (1%)
 Frame = +3

Query: 73  DTNSDGTIDFREFIIALSVTSRGK-LEQKLKWAFSMYDLDGNGYISRSEMLEIVQAIYKM 131
           D + +GTIDF EF+  ++   +    E++L+ AF ++D DGNGYIS +E+  ++  +   
Sbjct: 579 DADGNGTIDFEEFLHMMARKMKDTDCEEELREAFRVFDKDGNGYISAAELRHVMTNL--- 749

Query: 132 VSSVMKMPEDESTPEKRTDKIFRQMDTNNDGKLSLEEFI 170
                     E   ++  D++ ++ D + DG ++ EEF+
Sbjct: 750 ---------GEKLTDEEVDEMIKEADLDGDGMVNYEEFV 839

 Score = 31.2 bits (69), Expect = 0.24,   Method: Compositional matrix adjust.
 Identities = 24/105 (22%), Positives = 45/105 (42%)
 Frame = +3

Query: 23  TDHELQEWYKGFLKDCPTGHLTVDEFKKIYANFFPYGDASKFAEHVFRTFDTNSDGTIDF 82
           T++ELQ+       D   G +  +EF  + A      D  +     FR FD + +G I  
Sbjct: 543 TENELQDMINEVDAD-GNGTIDFEEFLHMMARKMKDTDCEEELREAFRVFDKDGNGYISA 719

Query: 83  REFIIALSVTSRGKLEQKLKWAFSMYDLDGNGYISRSEMLEIVQA 127
            E    ++       ++++       DLDG+G ++  E + ++ A
Sbjct: 720 AELRHVMTNLGEKLTDEEVDEMIKEADLDGDGMVNYEEFVTMMTA 854
>05237
          Length = 472

 Score = 44.3 bits (103), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 22/74 (29%), Positives = 42/74 (56%)
 Frame = +3

Query: 98  EQKLKWAFSMYDLDGNGYISRSEMLEIVQAIYKMVSSVMKMPEDESTPEKRTDKIFRQMD 157
           + +L+ AF ++D DGNG+IS SE+  ++  +             E   ++  D++ R+ D
Sbjct: 24  DDELREAFRVFDKDGNGFISASELRHVMTNLG------------EKLTDEEVDEMIREAD 167

Query: 158 TNNDGKLSLEEFIK 171
            + DG+++ EEF+K
Sbjct: 168 IDGDGQVNYEEFVK 209
>18571
          Length = 821

 Score = 42.7 bits (99), Expect = 9e-05,   Method: Compositional matrix adjust.
 Identities = 21/38 (55%), Positives = 24/38 (63%)
 Frame = -2

Query: 153 FRQMDTNNDGKLSLEEFIKGAKSDPSIVRLLQCDPSSA 190
           FRQMD N DGKLSLEEFI+G  + P +       PS A
Sbjct: 811 FRQMDKNLDGKLSLEEFIEGP*TIPPLFDFCSVTPSRA 698
>07198
          Length = 1675

 Score = 40.0 bits (92), Expect = 6e-04,   Method: Compositional matrix adjust.
 Identities = 34/125 (27%), Positives = 51/125 (40%)
 Frame = -3

Query: 49  KKIYANFFPYGDASKFAEHVFRTFDTNSDGTIDFREFIIALSVTSRGKLEQKLKWAFSMY 108
           K+ +A F P        E   R  D N DGTI   EF   +   + G      + +F  Y
Sbjct: 422 KEYFAFFMPNSFPQLELERFMRQSDKNKDGTISMEEF---MPEGATGDTRTSSEESFKNY 252

Query: 109 DLDGNGYISRSEMLEIVQAIYKMVSSVMKMPEDESTPEKRTDKIFRQMDTNNDGKLSLEE 168
           D D +G +S  E +E +             P  +   +   + +F   D N+DGKLS +E
Sbjct: 251 DKDKDGSLSLEEAMEWIN------------PSSDEHADVEVEHLFTIGDVNHDGKLSKDE 108

Query: 169 FIKGA 173
            +  A
Sbjct: 107 ILNKA 93
>07678
          Length = 958

 Score = 40.0 bits (92), Expect = 6e-04,   Method: Compositional matrix adjust.
 Identities = 39/132 (29%), Positives = 60/132 (45%), Gaps = 5/132 (3%)
 Frame = +1

Query: 43  LTVDEFKKIYANFFPYGDASKFAEHVFRTFDTNSDGTIDFREFIIALSVTSRGKLEQKLK 102
           L   EFKK    F          + +F  FD +  GTIDF EF++ L        +  ++
Sbjct: 370 LDFKEFKKGITEFGLTQFEGDVIQEMFTCFDKDZSGTIDFDEFLVKLRPPMSQMRKDLIQ 549

Query: 103 WAFSMYDLDGNGYISRSEMLEIVQAIYKMVSSVMKMPE--DESTPEKRTDKIF-RQMDTN 159
            AF   D  G+G ++  ++        K V +V K P+  +    E+R  +IF    D+ 
Sbjct: 550 RAFQKLDKTGDGVVTVEDL--------KGVYNVTKHPKYLNGEWTEERILRIFLDSFDSP 705

Query: 160 N--DGKLSLEEF 169
           N  DGK++ EEF
Sbjct: 706 NDKDGKITKEEF 741
>01019
          Length = 1705

 Score = 39.3 bits (90), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 18/69 (26%), Positives = 37/69 (53%)
 Frame = +1

Query: 102 KWAFSMYDLDGNGYISRSEMLEIVQAIYKMVSSVMKMPEDESTPEKRTDKIFRQMDTNND 161
           +W   ++D DGNG+IS +E+  ++  +             E   ++  D++ R+ D + D
Sbjct: 28  EWPLLVFDKDGNGFISAAELRHVMTNL------------GEKLTDEEVDEMIREADIDGD 171

Query: 162 GKLSLEEFI 170
           G+++ EEF+
Sbjct: 172 GQVNYEEFV 198
>00167
          Length = 2176

 Score = 38.9 bits (89), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 20/56 (35%), Positives = 32/56 (57%)
 Frame = +3

Query: 67  HVFRTFDTNSDGTIDFREFIIALSVTSRGKLEQKLKWAFSMYDLDGNGYISRSEML 122
            VFR FD +  GT+DF EF++AL         + +K AF+  D  G+G I+  +++
Sbjct: 852 EVFRRFDKDGTGTLDFEEFLLALRPKMNEFRRKLVKKAFAKMDKTGDGIITADDLV 1019

 Score = 29.6 bits (65), Expect = 0.89,   Method: Compositional matrix adjust.
 Identities = 13/22 (59%), Positives = 16/22 (72%)
 Frame = +3

Query: 153 FRQMDTNNDGKLSLEEFIKGAK 174
           FR MD N D KLS++EFI G +
Sbjct: 747 FRIMDDNRDRKLSVDEFIVGCR 812
>14366
          Length = 499

 Score = 36.6 bits (83), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 18/71 (25%), Positives = 40/71 (56%)
 Frame = -3

Query: 101 LKWAFSMYDLDGNGYISRSEMLEIVQAIYKMVSSVMKMPEDESTPEKRTDKIFRQMDTNN 160
           L+ AF ++D +GNG I+ +E+  ++  + + +S            ++  D++ R+ D + 
Sbjct: 245 LREAFRIFDKEGNGMINAAELRHVLTHLGEKLS------------DEEVDEMIREADISG 102

Query: 161 DGKLSLEEFIK 171
           DG++S  +F+K
Sbjct: 101 DGQVSYNDFVK 69
>15966
          Length = 362

 Score = 36.2 bits (82), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 32/112 (28%), Positives = 45/112 (40%), Gaps = 1/112 (0%)
 Frame = +2

Query: 60  DASKFAEHV-FRTFDTNSDGTIDFREFIIALSVTSRGKLEQKLKWAFSMYDLDGNGYISR 118
           D S+ + H  F    +  D  I F EF   L         QKL   F   D  G+GY+ R
Sbjct: 20  DESRRSRHARFFVVPSCGDKRITFEEFCKGLDQIVM--FVQKLAELFKAKDKSGDGYLDR 193

Query: 119 SEMLEIVQAIYKMVSSVMKMPEDESTPEKRTDKIFRQMDTNNDGKLSLEEFI 170
            E+  ++        S  K   D+ +       I +  D NND K+  EEF+
Sbjct: 194 DELKALLD------ESGQKFTADDVSA------ILKSADKNNDNKICFEEFV 313
>01773
          Length = 1950

 Score = 35.0 bits (79), Expect = 0.019,   Method: Compositional matrix adjust.
 Identities = 35/131 (26%), Positives = 53/131 (40%), Gaps = 1/131 (0%)
 Frame = +1

Query: 41  GHLTVDEFKKIYANFFPYGDASKFAEHVFRTFDT-NSDGTIDFREFIIALSVTSRGKLEQ 99
           G+L + E ++++         S+ A+  F  FD    D  I F  F   L         Q
Sbjct: 199 GYLEIKELRELFKRNGSSLSDSQIAD-TFVFFDGPRGDKRITFEXFCKGLDQIVM--FVQ 369

Query: 100 KLKWAFSMYDLDGNGYISRSEMLEIVQAIYKMVSSVMKMPEDESTPEKRTDKIFRQMDTN 159
           KL   F   D  G+GY+ R E+  ++        S  K   D+ +       I +  D N
Sbjct: 370 KLAELFKAKDKSGDGYLDRDELKALLD------ESGQKFTADDVSA------ILKSADKN 513

Query: 160 NDGKLSLEEFI 170
           ND K+  EEF+
Sbjct: 514 NDNKICFEEFV 546
>38338
          Length = 463

 Score = 31.6 bits (70), Expect = 0.20,   Method: Compositional matrix adjust.
 Identities = 16/49 (32%), Positives = 23/49 (46%)
 Frame = -2

Query: 68  VFRTFDTNSDGTIDFREFIIALSVTSRGKLEQKLKWAFSMYDLDGNGYI 116
            F  FD + DGTI  +E    +    +   E +L+   +  D DGNG I
Sbjct: 153 AFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTI 7

 Score = 27.7 bits (60), Expect = 3.2,   Method: Compositional matrix adjust.
 Identities = 10/29 (34%), Positives = 21/29 (72%)
 Frame = -2

Query: 100 KLKWAFSMYDLDGNGYISRSEMLEIVQAI 128
           + K AFS++D DG+G I+  E+  +++++
Sbjct: 165 EFKEAFSLFDKDGDGTITTKELGTVMRSL 79
>33397
          Length = 1723

 Score = 31.6 bits (70), Expect = 0.24,   Method: Compositional matrix adjust.
 Identities = 14/27 (51%), Positives = 17/27 (62%)
 Frame = +3

Query: 143 STPEKRTDKIFRQMDTNNDGKLSLEEF 169
           STP +  +  FR  D N DG+L LEEF
Sbjct: 180 STPPRNFEIAFRMFDINGDGELDLEEF 260

 Score = 28.1 bits (61), Expect = 2.5,   Method: Compositional matrix adjust.
 Identities = 18/67 (26%), Positives = 32/67 (47%)
 Frame = +3

Query: 78  GTIDFREFIIALSVTSRGKLEQKLKWAFSMYDLDGNGYISRSEMLEIVQAIYKMVSSVMK 137
           G I F ++I  L+V S     +  + AF M+D++G+G +   E    VQ + +  + V  
Sbjct: 135 GLISFSDYIFLLTVLS--TPPRNFEIAFRMFDINGDGELDLEE-FNRVQGVIRNQTHVGA 305

Query: 138 MPEDEST 144
              D + 
Sbjct: 306 RHRDHAV 326

 Score = 27.3 bits (59), Expect = 4.1,   Method: Compositional matrix adjust.
 Identities = 21/74 (28%), Positives = 33/74 (44%), Gaps = 2/74 (2%)
 Frame = +2

Query: 103 WAF--SMYDLDGNGYISRSEMLEIVQAIYKMVSSVMKMPEDESTPEKRTDKIFRQMDTNN 160
           W F  S+ D+D          + I +  +  V+  + M +     E   D +F   D NN
Sbjct: 635 WKFLKSINDIDTALSFYHLAGVSIDRETFHHVAKTVAMAD---LTEHVIDVVFTLFDENN 805

Query: 161 DGKLSLEEFIKGAK 174
           DG+LS +EF+   K
Sbjct: 806 DGELSNKEFVSVMK 847
>08380
          Length = 1236

 Score = 29.6 bits (65), Expect = 0.77,   Method: Compositional matrix adjust.
 Identities = 29/136 (21%), Positives = 57/136 (41%), Gaps = 24/136 (17%)
 Frame = -1

Query: 58  YGDASKFAEHVFRTFDTNSDGTIDFREFIIAL--------SVTSRGKL------------ 97
           + +A++  E +F+  D +++G + ++E+ +           V SR  +            
Sbjct: 783 FSEATQENEEIFKHLDPDNNGKVHWKEYYVHFLLAKGYKQDVASRHVVDYDZIQLDPDAK 604

Query: 98  EQKLKWAFSMYDLDG---NGYISRSEMLEIVQAIYKMVSSVMKMPED-ESTPEKRTDKIF 153
           E+ +++ F   D DG   +  ++R E +              + PE  E T     + I 
Sbjct: 603 EEIIRYKFRWSDADGEPMDNELTREEFMSF------------RHPEQSEKTLNNMVNGIL 460

Query: 154 RQMDTNNDGKLSLEEF 169
             +DTN DG ++ EEF
Sbjct: 459 GGIDTNGDGVVTEEEF 412
>01401
          Length = 1454

 Score = 28.9 bits (63), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 10/28 (35%), Positives = 18/28 (64%)
 Frame = +1

Query: 152 IFRQMDTNNDGKLSLEEFIKGAKSDPSI 179
           +FRQ+D +N G L+ EE +   +S+  +
Sbjct: 277 VFRQLDKDNSGSLTREEIMAAVQSEGEL 360
>17484
          Length = 471

 Score = 28.5 bits (62), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 17/59 (28%), Positives = 28/59 (47%)
 Frame = -1

Query: 108 YDLDGNGYISRSEMLEIVQAIYKMVSSVMKMPEDESTPEKRTDKIFRQMDTNNDGKLSL 166
           YD DGNG I+R+E   +V+ +              S  EK  +++ +  DT+  G + L
Sbjct: 465 YDQDGNGKITRNEFRSVVRML------------GHSLSEKELEEMMQAADTDASGAIEL 325
>32088
          Length = 1928

 Score = 28.1 bits (61), Expect = 2.1,   Method: Compositional matrix adjust.
 Identities = 21/70 (30%), Positives = 35/70 (50%)
 Frame = +1

Query: 100  KLKWAFSMYDLDGNGYISRSEMLEIVQAIYKMVSSVMKMPEDESTPEKRTDKIFRQMDTN 159
            +L+  F   D D NG+IS  E+    +A+       + +P      E RT  I  + D +
Sbjct: 946  ELRSVFDSIDDDNNGHISXGELDSAFRAVG------LNIP----GYELRT--IMSKYDAS 1089

Query: 160  NDGKLSLEEF 169
             DG+L+++EF
Sbjct: 1090 GDGRLNMDEF 1119
>07385
          Length = 1292

 Score = 27.3 bits (59), Expect = 3.8,   Method: Compositional matrix adjust.
 Identities = 9/23 (39%), Positives = 17/23 (73%)
 Frame = +3

Query: 149 TDKIFRQMDTNNDGKLSLEEFIK 171
            D++ R+ D + DG+++ EEF+K
Sbjct: 168 VDEMIREADIDGDGQVNYEEFVK 236
>26849
          Length = 649

 Score = 27.3 bits (59), Expect = 4.2,   Method: Compositional matrix adjust.
 Identities = 17/52 (32%), Positives = 30/52 (57%), Gaps = 1/52 (1%)
 Frame = +2

Query: 43  LTVDEFKK-IYANFFPYGDASKFAEHVFRTFDTNSDGTIDFREFIIALSVTS 93
           L+++EFKK I        +A    E +F  FD + +GTI+  EF++ ++ T+
Sbjct: 218 LSLEEFKKGILDMHIDINEAD--IEDMFYRFDNDGNGTINMTEFLLKVASTN 367
>28870
          Length = 846

 Score = 26.9 bits (58), Expect = 5.5,   Method: Compositional matrix adjust.
 Identities = 17/51 (33%), Positives = 25/51 (49%), Gaps = 2/51 (3%)
 Frame = -3

Query: 141 DESTPEKRTDKIFRQM--DTNNDGKLSLEEFIKGAKSDPSIVRLLQCDPSS 189
           D S   +R   +F  +  DTN  G+ S  E  + +  D   + +L CDPSS
Sbjct: 799 DTSLDSRRCSSVFSDVKSDTNGKGRQSGWEDGESSDEDDGGLGMLDCDPSS 647
>22273
          Length = 297

 Score = 26.6 bits (57), Expect = 5.9,   Method: Compositional matrix adjust.
 Identities = 9/23 (39%), Positives = 17/23 (73%)
 Frame = +1

Query: 149 TDKIFRQMDTNNDGKLSLEEFIK 171
            D++ R+ D + DG+++ EEF+K
Sbjct: 1   VDEMIREADIDGDGQVNYEEFVK 69
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|82930262|ref|XP_620758.2| PREDICTED: vacuolar protein
sorting 13C isoform 1 [Mus musculus]
         (3748 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

17848                                                                  70   2e-11
>17848
          Length = 449

 Score = 69.7 bits (169), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 46/153 (30%), Positives = 76/153 (49%), Gaps = 11/153 (7%)
 Frame = +2

Query: 2149 LKVLACPFLRERRGKSITTVLQPCSLFMEKCTWASGKQNINIVVKEFVIKISPIILNTVM 2208
            L++ +C F  +RR +  T VL PC L        S   ++++ + + V+ ISP  + T+ 
Sbjct: 5    LQIFSCTF--DRRLQHHTQVLMPCDLSFHSNAKESKNPHMDVSISDIVLNISPATIATMA 178

Query: 2209 TIMAAMSPKTKEDEWKDTPKETDNLWAVKSITDYNSWFLG-----------VDMATEVTE 2257
             + A +SP++ + E        ++LWAVK I D N WFL            +D+A+ ++ 
Sbjct: 179  AVSAGLSPQSGDAEQVKREVIPEHLWAVKRIIDCNFWFLDTVKVASEEELKLDLASPLSS 358

Query: 2258 NFRDSEHPSIEENCVVAVESVQVTLECGLGHRT 2290
               D+      E  VV + S+ V LE G+G RT
Sbjct: 359  ADMDATR---GEELVVNLPSIVVKLEGGIGRRT 448
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|94399169|ref|XP_001002428.1| PREDICTED: similar to
Plexin-B2 precursor (MM1) isoform 25 [Mus musculus]
         (1842 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

38765                                                                  69   2e-11
17589                                                                  40   0.013
28520                                                                  37   0.057
30668                                                                  36   0.12 
27845                                                                  36   0.12 
20181                                                                  33   1.1  
08626                                                                  33   1.1  
33760                                                                  32   2.4  
08465                                                                  32   2.5  
37883                                                                  32   2.5  
35046                                                                  31   3.7  
26675                                                                  30   6.8  
27299                                                                  30   9.0  
>38765
          Length = 756

 Score = 68.6 bits (166), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 49/193 (25%), Positives = 92/193 (47%), Gaps = 19/193 (9%)
 Frame = +3

Query: 93  TDNFNQLLLLDPPGKRLVECGSLFKGICALRAMSNIS-VRLFYEDGSGEKSFVASNDERV 151
           TDN+N++LLLD   + L+ CGS+++G C  R+++NIS V+ +Y         VA+N    
Sbjct: 27  TDNYNKILLLDHAQRMLITCGSVYQGACETRSLANISHVQEYYSADDVTDFAVAANSRNA 206

Query: 152 ATVGLVTSTRPDGERVLFV-----GKGNGP---HDNGIIVSTRLLDR------AEGREAF 197
           +TV  +       + VL+V     G+        D    +S+R L +      A      
Sbjct: 207 STVAFIAPGSTHSQSVLYVAATYTGRSRTSRIYRDQVPALSSRSLKKQRPFSLAAVSNPL 386

Query: 198 EAYSDHTTFKAGYLSTNTQQFVAAFEDDFYVFFVF----NHQDKHPAKNRTLLARMCKDD 253
              S     K+   S    ++V AF    + +F+     + +D+   K  + + ++C+DD
Sbjct: 387 RGMSSSIYLKSEISSYFLIRYVTAFSYQGFSYFLTVQNDSVEDRATNKKVSKIVQICQDD 566

Query: 254 PSYYSYVEMDLQC 266
            +++SY ++ ++C
Sbjct: 567 SNFFSYADIPIKC 605
>17589
          Length = 456

 Score = 39.7 bits (91), Expect = 0.013,   Method: Compositional matrix adjust.
 Identities = 28/101 (27%), Positives = 49/101 (48%), Gaps = 4/101 (3%)
 Frame = +1

Query: 923  LDTGSKEDVRVTLNDVPCEVTKFG---AQLQCVTGQQLAP-GQVTLEIYYGGSRVPSPGI 978
            L+TG +  ++  L D PC V         + C T +   P  +  +++++ G+R+ +   
Sbjct: 7    LNTGGQ--LKAVLGDAPCIVESKSLTPESVTCETTRVWRPEPKSPVQVFFDGARI-TLDR 177

Query: 979  SFTYCENPMIRAFEPLRSFVSGGRSINVTGQGFSLIQKFAM 1019
             F Y ++P+I    PL S   GGR + +TG     IQ+  M
Sbjct: 178  QFVYRDDPVITNILPLASIRQGGRMLTITGTDLGYIQQPQM 300
>28520
          Length = 446

 Score = 37.4 bits (85), Expect = 0.057,   Method: Compositional matrix adjust.
 Identities = 27/105 (25%), Positives = 51/105 (48%), Gaps = 13/105 (12%)
 Frame = +2

Query: 399 VTAEND--HTVAFLGTSDGRILKVYLAPDGTSAEYGSIPVD-----------INKKIKQD 445
           V A +D  + V F+GT DGR++K      G S++  ++ ++            + K+ +D
Sbjct: 128 VKAADDRYYDVMFVGTDDGRVIKA--VNKGQSSQIETVVIEDIRVFGEHDPVTDLKVFRD 301

Query: 446 LALSGNLSSLYAMTQDKVFRLPVQECLSYVTCAQCRDSQDPYCGW 490
            A    +  L  +++++V R      ++  TC  C + +DPYC W
Sbjct: 302 TA--KGIEQLVVISREEVGRPSPSTAVAQETCRACVELRDPYCVW 430
>30668
          Length = 686

 Score = 36.2 bits (82), Expect = 0.12,   Method: Composition-based stats.
 Identities = 17/44 (38%), Positives = 20/44 (45%)
 Frame = -2

Query: 1507 PCSCWPKPDSVVLEWRPGSTAQILSDLDLTSQREGRWKRINTLM 1550
            P SC   P +    W P S+   + D    SQR G W R  TLM
Sbjct: 619  PASCCGAPSATTRCWDPSSSKAWVLDAATASQRSGTWTRCCTLM 488
>27845
          Length = 384

 Score = 36.2 bits (82), Expect = 0.12,   Method: Composition-based stats.
 Identities = 27/79 (34%), Positives = 37/79 (46%), Gaps = 2/79 (2%)
 Frame = +1

Query: 725 FRTPKLSHDGNETLPLHLYVKSFGKNIDSKLQVTLYNCSFGRSDCSLCLAADPAYRCVWC 784
           FRT  L+ +  ET  L +  KSF          T YNCS   + CS C   D A+ C WC
Sbjct: 172 FRTVTLALNSTETGKLFV-TKSF----------TFYNCS-NFNTCSQC--TDSAFECHWC 309

Query: 785 RGQNRCVYEALC--SNVTS 801
              N C ++ +   SN+ +
Sbjct: 310 VYDNGCYHDTMACQSNIIA 366

 Score = 30.4 bits (67), Expect = 6.5,   Method: Composition-based stats.
 Identities = 12/27 (44%), Positives = 16/27 (59%)
 Frame = +1

Query: 471 CLSYVTCAQCRDSQDPYCGWCVIEGRC 497
           C ++ TC+QC DS    C WCV +  C
Sbjct: 250 CSNFNTCSQCTDSAFE-CHWCVYDNGC 327
>20181
          Length = 631

 Score = 33.1 bits (74), Expect = 1.1,   Method: Composition-based stats.
 Identities = 16/42 (38%), Positives = 21/42 (50%)
 Frame = -3

Query: 1686 NSLPLRFWVNILKNPHFIFDVHVHEVVDASLSVIAQTFMDAC 1727
            N   L FW  IL       D+H +EV+D  +SV+   F  AC
Sbjct: 317  NMFVLYFWNTILFKSKCSLDMHYNEVIDRKMSVV*VIFFPAC 192
>08626
          Length = 1547

 Score = 33.1 bits (74), Expect = 1.1,   Method: Composition-based stats.
 Identities = 16/42 (38%), Positives = 19/42 (45%)
 Frame = -3

Query: 1509 SCWPKPDSVVLEWRPGSTAQILSDLDLTSQREGRWKRINTLM 1550
            SC   P +    W P S+   + D    SQR G W R  TLM
Sbjct: 567  SCCGAPSATTRCWDPSSSKAWVLDAATASQRSGTWTRCCTLM 442
>33760
          Length = 495

 Score = 32.0 bits (71), Expect = 2.4,   Method: Composition-based stats.
 Identities = 18/53 (33%), Positives = 23/53 (43%)
 Frame = -1

Query: 454 SLYAMTQDKVFRLPVQECLSYVTCAQCRDSQDPYCGWCVIEGRCTRKSECSRA 506
           +LY  T   V +L V  C  Y+    C    DPYCGW      C   ++  RA
Sbjct: 291 TLYLGTDQSVVQLGVITCEVYLKVDLC--VYDPYCGWDAKTNLCVPATKGRRA 139
>08465
          Length = 815

 Score = 32.0 bits (71), Expect = 2.5,   Method: Composition-based stats.
 Identities = 15/44 (34%), Positives = 19/44 (43%)
 Frame = +3

Query: 1507 PCSCWPKPDSVVLEWRPGSTAQILSDLDLTSQREGRWKRINTLM 1550
            P SC     +    W P S+   + D    SQR G W R  TL+
Sbjct: 684  PASCCGAASATTRCWDPSSSKAWVLDAATASQRSGTWTRCCTLI 815
>37883
          Length = 820

 Score = 32.0 bits (71), Expect = 2.5,   Method: Compositional matrix adjust.
 Identities = 19/47 (40%), Positives = 24/47 (51%), Gaps = 2/47 (4%)
 Frame = +3

Query: 376 GSRDGLVATAVLHRGGLNLTAVTVTAENDH--TVAFLGTSDGRILKV 420
            S  G + T +     L  TAVT+T+  DH  T   L  SD R+LKV
Sbjct: 126 SSEKGTIETYLQQSSFLQSTAVTLTSAKDHKDTTVLLPQSDTRVLKV 266
>35046
          Length = 518

 Score = 31.2 bits (69), Expect = 3.7,   Method: Compositional matrix adjust.
 Identities = 23/64 (35%), Positives = 28/64 (43%), Gaps = 7/64 (10%)
 Frame = -1

Query: 960  GQVTLEIYYGGSRV-------PSPGISFTYCENPMIRAFEPLRSFVSGGRSINVTGQGFS 1012
            GQ T   Y   S V       PSP       ++P I   EP +S +SGG  I V G    
Sbjct: 482  GQTTRRTYRSASGVTRRPALNPSP-----TPKDPEITMIEPKKSILSGGTLITVLGARLD 318

Query: 1013 LIQK 1016
            LIQ+
Sbjct: 317  LIQR 306
>26675
          Length = 927

 Score = 30.4 bits (67), Expect = 6.8,   Method: Composition-based stats.
 Identities = 17/54 (31%), Positives = 23/54 (42%), Gaps = 6/54 (11%)
 Frame = -3

Query: 1499 IDQVYRTQPCSCWPKPDSVVLEWRPGSTAQILSDLDLTSQR------EGRWKRI 1546
            I Q+ +TQP + WP P S         TA + S +  T         E  W+RI
Sbjct: 334  ISQLMKTQPSTAWPSPQSKQRHLMG*GTASLASTMTWTGSPSMKALVESHWRRI 173
>27299
          Length = 864

 Score = 30.0 bits (66), Expect = 9.0,   Method: Compositional matrix adjust.
 Identities = 11/42 (26%), Positives = 22/42 (52%)
 Frame = -3

Query: 806 PVITRIQPETGPLGGGILVTIHGSNLGVKADDVKKITVAGQN 847
           P++T + P    + GG  + + G NLG+   D+ +  + G +
Sbjct: 841 PIVTNLIPNMATVHGGTRLCVEGKNLGLGKSDIMEFMLCGSD 716
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6754974|ref|NP_035991.1| protein kinase C and casein
kinase substrate in neurons 1 isoform 1 [Mus musculus]
         (441 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

14893                                                                  66   3e-11
17800                                                                  63   2e-10
28095                                                                  52   6e-07
29687                                                                  49   4e-06
01494                                                                  47   1e-05
16716                                                                  46   2e-05
12324                                                                  44   1e-04
13664                                                                  41   0.001
30482                                                                  40   0.001
15115                                                                  38   0.008
05206                                                                  32   0.43 
19469                                                                  32   0.66 
37074                                                                  30   1.4  
30899                                                                  30   2.0  
31183                                                                  29   4.2  
37027                                                                  28   6.4  
>14893
          Length = 403

 Score = 65.9 bits (159), Expect = 3e-11,   Method: Compositional matrix adjust.
 Identities = 41/133 (30%), Positives = 61/133 (45%), Gaps = 1/133 (0%)
 Frame = +1

Query: 220 YMEGMXXXXXXXXXXXXKRLVFLKEVLLDIKRHLNLAENSSYMHVYRELEQAIRGADAQE 279
           Y+E M             R+ F K     + + L+L+  S Y  VY +L   I   D   
Sbjct: 1   YIEDMTEVYDKCQEFERTRIEFFKATFFKLHKCLDLSVESEYARVYTDLHATITNTDPDR 180

Query: 280 DLRWFRSTSGPGMPMNWPQFEEWNPDLPHTTAKKEKQPKKAEGATLSNATGAVESTSQAG 339
           DL+++ ++ G  M M WPQFEE++P+L       +   KK +GA +S   G +  TS   
Sbjct: 181 DLKYWSTSHGIDMAMAWPQFEEYSPEL-------QAISKKGKGA-VSTGEGGITITSIRH 336

Query: 340 DR-GSVSSYDRGQ 351
            R  S  SY+  Q
Sbjct: 337 SRESSYGSYNSDQ 375
>17800
          Length = 451

 Score = 62.8 bits (151), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 38/133 (28%), Positives = 54/133 (40%), Gaps = 1/133 (0%)
 Frame = +2

Query: 213 VGKTTPQYMEGMXXXXXXXXXXXXKRLVFLKEVLLDIKRHLNLAENSSYMHVYRELEQAI 272
           + K    Y+E M             RL F KEVL ++   L+  +  S   +Y E    I
Sbjct: 2   ITKYNSVYIEDMTSVFEKCQTMEKTRLQFFKEVLFNVHSTLDTTKVQSLPQIYDEFYHTI 181

Query: 273 RGADAQEDLRWFRSTSGPGMPMNWPQFEEWNPDLPHTT-AKKEKQPKKAEGATLSNATGA 331
             AD Q+DL+W+ +  G  M MNWP F E+  +        K K+   A   TL N    
Sbjct: 182 NNADQQKDLKWWSNNHGINMAMNWPAFVEYTEEFRDIAKGNKSKEALPAAPITLINQRPV 361

Query: 332 VESTSQAGDRGSV 344
            E   +     S+
Sbjct: 362 AEDVHEYPSTNSL 400
>28095
          Length = 597

 Score = 51.6 bits (122), Expect = 6e-07,   Method: Compositional matrix adjust.
 Identities = 25/61 (40%), Positives = 39/61 (63%), Gaps = 1/61 (1%)
 Frame = +3

Query: 382 AKGVRVRALYDYDGQEQDELSFKAGDELTKLGEEDEQGWCRGRLD-SGQLGLYPANYVEA 440
           ++G+  +A+YDY   + DE+SF  GD + +    D  GW  GR++ +GQ G+ P+NYVE 
Sbjct: 249 SRGMVCKAMYDYQAADSDEVSFNDGDTIIECQPVD-AGWMTGRVERTGQYGMLPSNYVER 425

Query: 441 I 441
           I
Sbjct: 426 I 428
>29687
          Length = 434

 Score = 48.9 bits (115), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 27/66 (40%), Positives = 40/66 (60%)
 Frame = -2

Query: 376 NPFEDDAKGVRVRALYDYDGQEQDELSFKAGDELTKLGEEDEQGWCRGRLDSGQLGLYPA 435
           NP  D    +RV+AL+DY+ + +DELSF  G  +T +  +D  GW RG   + +   +P+
Sbjct: 322 NP-NDFTTKLRVKALHDYNAKREDELSFCKGAIITNVSRQD-GGWWRGDYGTKKQHWFPS 149

Query: 436 NYVEAI 441
           NYVE I
Sbjct: 148 NYVEEI 131
>01494
          Length = 2122

 Score = 47.4 bits (111), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 29/86 (33%), Positives = 46/86 (53%)
 Frame = +3

Query: 356 EWSDDESGNPFGGNEANGGANPFEDDAKGVRVRALYDYDGQEQDELSFKAGDELTKLGEE 415
           + + DE+G  +G  +     N F      +RV+AL+DY+    DELSF  G  +T +  +
Sbjct: 231 DMAPDETGI-YGAPDVYINPNDF---TTKLRVKALHDYNANRDDELSFCKGAIITNVSRQ 398

Query: 416 DEQGWCRGRLDSGQLGLYPANYVEAI 441
           D  GW RG   + +   +P+N+VE I
Sbjct: 399 D-GGWWRGDYGAKKQHWFPSNFVEEI 473
>16716
          Length = 934

 Score = 46.2 bits (108), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 26/56 (46%), Positives = 33/56 (58%)
 Frame = -1

Query: 384 GVRVRALYDYDGQEQDELSFKAGDELTKLGEEDEQGWCRGRLDSGQLGLYPANYVE 439
           G    ALYDY   + DEL+F   D +T +   D+ GW RG    G+ GL+PANYVE
Sbjct: 472 GSTAIALYDYQAADDDELTFDPDDVITDIEMIDD-GWWRGSC-HGKNGLFPANYVE 311
>12324
          Length = 946

 Score = 44.3 bits (103), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 22/54 (40%), Positives = 35/54 (64%)
 Frame = +3

Query: 386 RVRALYDYDGQEQDELSFKAGDELTKLGEEDEQGWCRGRLDSGQLGLYPANYVE 439
           +V A+YDY+ ++ DEL+F     +  + + D+ GW  G +D G  GL+P+NYVE
Sbjct: 693 KVVAIYDYEAEKDDELTFSENSVIYVIRKNDD-GWWEGVMD-GVTGLFPSNYVE 848
>13664
          Length = 507

 Score = 40.8 bits (94), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 22/57 (38%), Positives = 29/57 (50%)
 Frame = +2

Query: 376 NPFEDDAKGVRVRALYDYDGQEQDELSFKAGDELTKLGEEDEQGWCRGRLDSGQLGL 432
           +P     K  +V ALYDY  Q  DEL+  +GD +  L  +D + W  G L  GQ G 
Sbjct: 338 SPLGSTRKPKKVVALYDYKAQRSDELTILSGDVIMLL-HKDSESWWMGELLDGQQGF 505
>30482
          Length = 610

 Score = 40.4 bits (93), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 22/72 (30%), Positives = 36/72 (50%), Gaps = 5/72 (6%)
 Frame = +3

Query: 373 GGANPFEDDA--KGVRVRALYDYDGQEQDELSFKAGDELTKLGEEDEQG---WCRGRLDS 427
           G  +PF   +  K  R RAL+ ++ + +DEL+   GD++       E G   W +G    
Sbjct: 81  GTTDPFAGGSGIKKTRYRALFPFESRSEDELNINTGDDIWVWDVPSEPGMEEWFKGETKD 260

Query: 428 GQLGLYPANYVE 439
           G++G +P  Y E
Sbjct: 261 GKVGWFPQAYAE 296
>15115
          Length = 443

 Score = 38.1 bits (87), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 17/42 (40%), Positives = 26/42 (61%)
 Frame = -2

Query: 400 ELSFKAGDELTKLGEEDEQGWCRGRLDSGQLGLYPANYVEAI 441
           E++F   D +T + + DE GW +G    G  G++PANYVE +
Sbjct: 412 EITFDPDDIITNIDQIDE-GWWQGFAPDGSYGMFPANYVELL 290
>05206
          Length = 1075

 Score = 32.3 bits (72), Expect = 0.43,   Method: Compositional matrix adjust.
 Identities = 20/79 (25%), Positives = 36/79 (45%), Gaps = 3/79 (3%)
 Frame = +1

Query: 365 PFGGNEANGGANPFEDDAKGVRV---RALYDYDGQEQDELSFKAGDELTKLGEEDEQGWC 421
           P  G+E   G    + + + + +   RALY ++   +  +     +E+  L E+   GW 
Sbjct: 22  PIDGDEEEFGDGDLDGEGEFIVIGTCRALYPFEAMNEGSVPMGENEEMQILEEDQGDGWT 201

Query: 422 RGRLDSGQLGLYPANYVEA 440
           R R   G  G  P++YV+ 
Sbjct: 202 RVRKADGSEGFVPSSYVQC 258
>19469
          Length = 428

 Score = 31.6 bits (70), Expect = 0.66,   Method: Compositional matrix adjust.
 Identities = 22/59 (37%), Positives = 33/59 (55%), Gaps = 5/59 (8%)
 Frame = -1

Query: 388 RALYDYDGQEQDELSFKAGDELTKLGEEDEQ---GW--CRGRLDSGQLGLYPANYVEAI 441
           +ALYD   +  DEL+F+ GD +T L E+D     GW  C  R   G+ G+ P N ++ +
Sbjct: 356 KALYDNIAETPDELAFRRGDVITIL-EQDTAGLDGWWLCSLR---GRQGIAPGNRLKIL 192
>37074
          Length = 1342

 Score = 30.4 bits (67), Expect = 1.4,   Method: Compositional matrix adjust.
 Identities = 14/45 (31%), Positives = 22/45 (48%)
 Frame = +1

Query: 34  RLCNDLMSCVQERAKIEKAYAQQLTDWAKRWRQLIEKGPQYGSLE 78
           + C D  + +++RAK+ K      +D  K  R L  KG  YG  +
Sbjct: 487 KAC-DFFTAMRQRAKLSKMAPPSYSDLGKAARDLFSKGYNYGFFK 618
>30899
          Length = 698

 Score = 30.0 bits (66), Expect = 2.0,   Method: Compositional matrix adjust.
 Identities = 11/20 (55%), Positives = 17/20 (85%)
 Frame = -2

Query: 386 RVRALYDYDGQEQDELSFKA 405
           +VRALYD++  E +EL+F+A
Sbjct: 61  KVRALYDFEAAEDNELTFQA 2
>31183
          Length = 923

 Score = 28.9 bits (63), Expect = 4.2,   Method: Compositional matrix adjust.
 Identities = 16/33 (48%), Positives = 21/33 (63%)
 Frame = +1

Query: 407 DELTKLGEEDEQGWCRGRLDSGQLGLYPANYVE 439
           D +T + E  + GW RG    G+ GL+PANYVE
Sbjct: 4   DVITDI-EMIDDGWWRGSC-HGKNGLFPANYVE 96
>37027
          Length = 704

 Score = 28.1 bits (61), Expect = 6.4,   Method: Compositional matrix adjust.
 Identities = 15/31 (48%), Positives = 15/31 (48%)
 Frame = +1

Query: 14  DSFWEVGNYKRTVKRIDDGHRLCNDLMSCVQ 44
           DS W VGN       ID    LCN L  CVQ
Sbjct: 313 DSCWTVGN------NIDSSFTLCNRLCVCVQ 387
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|82917305|ref|XP_486103.3| PREDICTED:
Arg/Abl-interacting protein ArgBP2 isoform 1 [Mus musculus]
         (1272 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

17286                                                                  67   3e-11
20131                                                                  62   1e-09
12324                                                                  57   6e-08
16716                                                                  52   1e-06
28095                                                                  49   1e-05
29243                                                                  44   4e-04
04501                                                                  44   4e-04
13664                                                                  41   0.003
18050                                                                  41   0.003
30740                                                                  39   0.009
19469                                                                  39   0.012
29687                                                                  39   0.014
01494                                                                  39   0.016
27252                                                                  39   0.018
26032                                                                  37   0.039
38574                                                                  33   0.044
31183                                                                  36   0.091
11228                                                                  34   0.34 
13641                                                                  34   0.45 
15115                                                                  33   0.59 
18881                                                                  32   1.3  
33143                                                                  32   1.7  
02941                                                                  30   7.1  
>17286
          Length = 489

 Score = 67.4 bits (163), Expect = 3e-11,   Method: Composition-based stats.
 Identities = 25/51 (49%), Positives = 40/51 (78%)
 Frame = +3

Query: 1040 AKAVYDFKAQTSKELSFKKGDTVYILRKIDQNWYEGEHHGRVGIFPISYVE 1090
            A+A+YDF  ++  EL F++GD + ++ ++D+NW+EG  HG+VG FPI+YVE
Sbjct: 30   ARAIYDFLPESDGELGFQEGDMITLISQVDENWFEGSVHGKVGYFPINYVE 182

 Score = 54.7 bits (130), Expect = 2e-07,   Method: Composition-based stats.
 Identities = 25/55 (45%), Positives = 39/55 (70%)
 Frame = +3

Query: 1115 AIAKYNFNADTNVELSLRKGDRIILLKRVDQNWYEGKIPGTNRQGIFPVSYVEVV 1169
            A A Y+F  +++ EL  ++GD I L+ +VD+NW+EG + G  + G FP++YVEVV
Sbjct: 30   ARAIYDFLPESDGELGFQEGDMITLISQVDENWFEGSVHG--KVGYFPINYVEVV 188

 Score = 40.0 bits (92), Expect = 0.005,   Method: Composition-based stats.
 Identities = 17/52 (32%), Positives = 32/52 (61%)
 Frame = +3

Query: 1219 QALYNYTPRNEDELELRESDVVDVMEKCDDGWFVGTSRRTKFFGTFPGNYVK 1270
            +A+Y++ P ++ EL  +E D++ ++ + D+ WF G+       G FP NYV+
Sbjct: 33   RAIYDFLPESDGELGFQEGDMITLISQVDENWFEGSVHGK--VGYFPINYVE 182
>20131
          Length = 574

 Score = 62.0 bits (149), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 41/149 (27%), Positives = 74/149 (49%), Gaps = 3/149 (2%)
 Frame = -2

Query: 1042 AVYDFKAQTSKELSFKKGDTVYILRKIDQNWYEGEHHGRVGIFPISYVEKLTXXXXXXXX 1101
            A+Y + +  + +L+F +GD + + +K D++W+ G    + G+FP +YV+K+         
Sbjct: 468  AMYSYVSGETADLTFNEGDMILVTKK-DEDWWTGTLGEKTGMFPSTYVKKVEIQPGQKSA 292

Query: 1102 XXXXXXXXGEIGEAIAKYNFNADTNVELSLRKGDRIILLKRVDQNWYEGKIPGTNRQ--- 1158
                     EI   IA Y   A  N +LSL  G+ I + ++  + W+EG++    ++   
Sbjct: 291  KKP------EIAMVIAPY--TATGNGQLSLEPGNLIHVRQKSPRGWWEGELQARGQRKKI 136

Query: 1159 GIFPVSYVEVVKRNAKGAEDYPDPPLPHS 1187
            G FP  YV+ +   +  A   PDP +  S
Sbjct: 135  GWFPADYVKPL--GSSSARSTPDPKVALS 55

 Score = 38.9 bits (89), Expect = 0.015,   Method: Compositional matrix adjust.
 Identities = 19/58 (32%), Positives = 30/58 (51%)
 Frame = -2

Query: 1215 GEPFQALYNYTPRNEDELELRESDVVDVMEKCDDGWFVGTSRRTKFFGTFPGNYVKRL 1272
            GE + A+Y+Y      +L   E D++ V +K +D W      +T   G FP  YVK++
Sbjct: 483  GEYYVAMYSYVSGETADLTFNEGDMILVTKKDEDWWTGTLGEKT---GMFPSTYVKKV 319

 Score = 36.6 bits (83), Expect = 0.073,   Method: Compositional matrix adjust.
 Identities = 17/58 (29%), Positives = 31/58 (53%), Gaps = 5/58 (8%)
 Frame = -2

Query: 1040 AKAVYDFKAQTSKELSFKKGDTVYILRKIDQNWYEGEHHGR-----VGIFPISYVEKL 1092
            A  +  + A  + +LS + G+ +++ +K  + W+EGE   R     +G FP  YV+ L
Sbjct: 276  AMVIAPYTATGNGQLSLEPGNLIHVRQKSPRGWWEGELQARGQRKKIGWFPADYVKPL 103
>12324
          Length = 946

 Score = 56.6 bits (135), Expect = 6e-08,   Method: Compositional matrix adjust.
 Identities = 21/49 (42%), Positives = 33/49 (67%)
 Frame = +3

Query: 1042 AVYDFKAQTSKELSFKKGDTVYILRKIDQNWYEGEHHGRVGIFPISYVE 1090
            A+YD++A+   EL+F +   +Y++RK D  W+EG   G  G+FP +YVE
Sbjct: 702  AIYDYEAEKDDELTFSENSVIYVIRKNDDGWWEGVMDGVTGLFPSNYVE 848

 Score = 45.1 bits (105), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 21/51 (41%), Positives = 29/51 (56%)
 Frame = +3

Query: 1220 ALYNYTPRNEDELELRESDVVDVMEKCDDGWFVGTSRRTKFFGTFPGNYVK 1270
            A+Y+Y    +DEL   E+ V+ V+ K DDGW+ G        G FP NYV+
Sbjct: 702  AIYDYEAEKDDELTFSENSVIYVIRKNDDGWWEGVMDGVT--GLFPSNYVE 848
>16716
          Length = 934

 Score = 52.4 bits (124), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 30/88 (34%), Positives = 42/88 (47%)
 Frame = -1

Query: 1183 PLPHSYSSDRIYTLSSNKPQRPGFSHENIQGGGEPFQALYNYTPRNEDELELRESDVVDV 1242
            P P     +  Y ++  +P  P  S     GGG    ALY+Y   ++DEL     DV+  
Sbjct: 559  PAPQHEPEESPYEMADEEPAAPAQSQ---PGGGSTAIALYDYQAADDDELTFDPDDVITD 389

Query: 1243 MEKCDDGWFVGTSRRTKFFGTFPGNYVK 1270
            +E  DDGW+ G+       G FP NYV+
Sbjct: 388  IEMIDDGWWRGSCHGKN--GLFPANYVE 311

 Score = 52.4 bits (124), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 21/51 (41%), Positives = 31/51 (60%)
 Frame = -1

Query: 1040 AKAVYDFKAQTSKELSFKKGDTVYILRKIDQNWYEGEHHGRVGIFPISYVE 1090
            A A+YD++A    EL+F   D +  +  ID  W+ G  HG+ G+FP +YVE
Sbjct: 463  AIALYDYQAADDDELTFDPDDVITDIEMIDDGWWRGSCHGKNGLFPANYVE 311

 Score = 44.3 bits (103), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 20/54 (37%), Positives = 31/54 (57%)
 Frame = -1

Query: 1115 AIAKYNFNADTNVELSLRKGDRIILLKRVDQNWYEGKIPGTNRQGIFPVSYVEV 1168
            AIA Y++ A  + EL+    D I  ++ +D  W+ G   G N  G+FP +YVE+
Sbjct: 463  AIALYDYQAADDDELTFDPDDVITDIEMIDDGWWRGSCHGKN--GLFPANYVEL 308
>28095
          Length = 597

 Score = 48.9 bits (115), Expect = 1e-05,   Method: Composition-based stats.
 Identities = 22/54 (40%), Positives = 34/54 (62%), Gaps = 2/54 (3%)
 Frame = +3

Query: 1041 KAVYDFKAQTSKELSFKKGDTVYILRKIDQNWYEG--EHHGRVGIFPISYVEKL 1092
            KA+YD++A  S E+SF  GDT+   + +D  W  G  E  G+ G+ P +YVE++
Sbjct: 267  KAMYDYQAADSDEVSFNDGDTIIECQPVDAGWMTGRVERTGQYGMLPSNYVERI 428

 Score = 46.2 bits (108), Expect = 8e-05,   Method: Composition-based stats.
 Identities = 18/54 (33%), Positives = 29/54 (53%)
 Frame = +3

Query: 1219 QALYNYTPRNEDELELRESDVVDVMEKCDDGWFVGTSRRTKFFGTFPGNYVKRL 1272
            +A+Y+Y   + DE+   + D +   +  D GW  G   RT  +G  P NYV+R+
Sbjct: 267  KAMYDYQAADSDEVSFNDGDTIIECQPVDAGWMTGRVERTGQYGMLPSNYVERI 428
>29243
          Length = 1147

 Score = 44.3 bits (103), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 20/58 (34%), Positives = 38/58 (65%), Gaps = 2/58 (3%)
 Frame = +2

Query: 1112 IGEAIAKYNFNADTNVELSLRKGDRIILLKR--VDQNWYEGKIPGTNRQGIFPVSYVE 1167
            +G A+A Y++ A +  +LS++  DRI +L +   D+ W++G+   T + G FP++YV+
Sbjct: 629  LGFAVAVYDYAATSTSQLSMKLNDRIAILSKNGQDKGWWKGENLRTQKIGYFPLAYVD 802
>04501
          Length = 575

 Score = 43.9 bits (102), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 17/37 (45%), Positives = 24/37 (64%), Gaps = 2/37 (5%)
 Frame = +3

Query: 149 YPGIGPVDESGIPTAIRTTVDRPK--DWYKTMFKQIH 183
           Y GIGP+D+ G+P A R  V   K  DWY+ M++ +H
Sbjct: 465 YDGIGPIDKEGVPLAFRKNVQEEKQHDWYRQMYRSLH 575
>13664
          Length = 507

 Score = 41.2 bits (95), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 16/35 (45%), Positives = 24/35 (68%)
 Frame = +2

Query: 1042 AVYDFKAQTSKELSFKKGDTVYILRKIDQNWYEGE 1076
            A+YD+KAQ S EL+   GD + +L K  ++W+ GE
Sbjct: 377  ALYDYKAQRSDELTILSGDVIMLLHKDSESWWMGE 481

 Score = 34.3 bits (77), Expect = 0.37,   Method: Compositional matrix adjust.
 Identities = 12/34 (35%), Positives = 21/34 (61%)
 Frame = +2

Query: 1220 ALYNYTPRNEDELELRESDVVDVMEKCDDGWFVG 1253
            ALY+Y  +  DEL +   DV+ ++ K  + W++G
Sbjct: 377  ALYDYKAQRSDELTILSGDVIMLLHKDSESWWMG 478
>18050
          Length = 448

 Score = 40.8 bits (94), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 21/53 (39%), Positives = 28/53 (52%)
 Frame = +3

Query: 1220 ALYNYTPRNEDELELRESDVVDVMEKCDDGWFVGTSRRTKFFGTFPGNYVKRL 1272
            A ++Y     D L+L   DVV+V  K  DGW+ G   R    G FPG+Y + L
Sbjct: 30   AKHSYESDEPDVLQLELGDVVNVSRKLPDGWYQGERIRDGAVGWFPGSYTEEL 188

 Score = 38.1 bits (87), Expect = 0.022,   Method: Compositional matrix adjust.
 Identities = 20/54 (37%), Positives = 29/54 (53%), Gaps = 2/54 (3%)
 Frame = +3

Query: 1042 AVYDFKAQTSKELSFKKGDTVYILRKIDQNWYEGE--HHGRVGIFPISYVEKLT 1093
            A + +++     L  + GD V + RK+   WY+GE    G VG FP SY E+L 
Sbjct: 30   AKHSYESDEPDVLQLELGDVVNVSRKLPDGWYQGERIRDGAVGWFPGSYTEELN 191

 Score = 33.9 bits (76), Expect = 0.48,   Method: Compositional matrix adjust.
 Identities = 17/54 (31%), Positives = 29/54 (53%)
 Frame = +3

Query: 1114 EAIAKYNFNADTNVELSLRKGDRIILLKRVDQNWYEGKIPGTNRQGIFPVSYVE 1167
            + IAK+++ +D    L L  GD + + +++   WY+G+       G FP SY E
Sbjct: 21   QVIAKHSYESDEPDVLQLELGDVVNVSRKLPDGWYQGERIRDGAVGWFPGSYTE 182
>30740
          Length = 488

 Score = 39.3 bits (90), Expect = 0.009,   Method: Compositional matrix adjust.
 Identities = 21/54 (38%), Positives = 33/54 (61%), Gaps = 1/54 (1%)
 Frame = +2

Query: 1035 KEKLPAKAVYDFKAQTSKELSFKKGDTVYILRKIDQNWYEG-EHHGRVGIFPIS 1087
            +EKL  K  YDF  +  ++L F KGD + ++ K ++ W+   + HGRVG  P+S
Sbjct: 182  REKLMGK--YDFSGRDPEDLPFSKGDILELISKDEEEWWTARDKHGRVGQDPLS 337
>19469
          Length = 428

 Score = 39.3 bits (90), Expect = 0.012,   Method: Compositional matrix adjust.
 Identities = 22/57 (38%), Positives = 32/57 (56%), Gaps = 4/57 (7%)
 Frame = -1

Query: 1033 PEKEKLPAKAVYDFKAQTSKELSFKKGDTVYILRK----IDQNWYEGEHHGRVGIFP 1085
            P  +   AKA+YD  A+T  EL+F++GD + IL +    +D  W+     GR GI P
Sbjct: 380  PLWQVFLAKALYDNIAETPDELAFRRGDVITILEQDTAGLD-GWWLCSLRGRQGIAP 213

 Score = 35.0 bits (79), Expect = 0.20,   Method: Compositional matrix adjust.
 Identities = 20/57 (35%), Positives = 31/57 (54%), Gaps = 3/57 (5%)
 Frame = -1

Query: 1219 QALYNYTPRNEDELELRESDVVDVMEKCD---DGWFVGTSRRTKFFGTFPGNYVKRL 1272
            +ALY+      DEL  R  DV+ ++E+     DGW++ + R  +  G  PGN +K L
Sbjct: 356  KALYDNIAETPDELAFRRGDVITILEQDTAGLDGWWLCSLRGRQ--GIAPGNRLKIL 192
>29687
          Length = 434

 Score = 38.9 bits (89), Expect = 0.014,   Method: Compositional matrix adjust.
 Identities = 20/57 (35%), Positives = 34/57 (59%), Gaps = 1/57 (1%)
 Frame = -2

Query: 1037 KLPAKAVYDFKAQTSKELSFKKGDTVYILRKIDQNWYEGEHHGRVG-IFPISYVEKL 1092
            KL  KA++D+ A+   ELSF KG  +  + + D  W+ G++  +    FP +YVE++
Sbjct: 301  KLRVKALHDYNAKREDELSFCKGAIITNVSRQDGGWWRGDYGTKKQHWFPSNYVEEI 131

 Score = 36.6 bits (83), Expect = 0.069,   Method: Compositional matrix adjust.
 Identities = 21/53 (39%), Positives = 29/53 (54%)
 Frame = -2

Query: 1117 AKYNFNADTNVELSLRKGDRIILLKRVDQNWYEGKIPGTNRQGIFPVSYVEVV 1169
            A +++NA    ELS  KG  I  + R D  W+ G   GT +Q  FP +YVE +
Sbjct: 286  ALHDYNAKREDELSFCKGAIITNVSRQDGGWWRGDY-GTKKQHWFPSNYVEEI 131

 Score = 34.3 bits (77), Expect = 0.37,   Method: Compositional matrix adjust.
 Identities = 18/54 (33%), Positives = 30/54 (55%)
 Frame = -2

Query: 1219 QALYNYTPRNEDELELRESDVVDVMEKCDDGWFVGTSRRTKFFGTFPGNYVKRL 1272
            +AL++Y  + EDEL   +  ++  + + D GW+ G    TK    FP NYV+ +
Sbjct: 289  KALHDYNAKREDELSFCKGAIITNVSRQDGGWWRG-DYGTKKQHWFPSNYVEEI 131
>01494
          Length = 2122

 Score = 38.5 bits (88), Expect = 0.016,   Method: Compositional matrix adjust.
 Identities = 19/57 (33%), Positives = 33/57 (57%), Gaps = 1/57 (1%)
 Frame = +3

Query: 1037 KLPAKAVYDFKAQTSKELSFKKGDTVYILRKIDQNWYEGEHHGRVG-IFPISYVEKL 1092
            KL  KA++D+ A    ELSF KG  +  + + D  W+ G++  +    FP ++VE++
Sbjct: 303  KLRVKALHDYNANRDDELSFCKGAIITNVSRQDGGWWRGDYGAKKQHWFPSNFVEEI 473

 Score = 36.6 bits (83), Expect = 0.069,   Method: Compositional matrix adjust.
 Identities = 19/54 (35%), Positives = 31/54 (57%)
 Frame = +3

Query: 1117 AKYNFNADTNVELSLRKGDRIILLKRVDQNWYEGKIPGTNRQGIFPVSYVEVVK 1170
            A +++NA+ + ELS  KG  I  + R D  W+ G   G  +Q  FP ++VE ++
Sbjct: 318  ALHDYNANRDDELSFCKGAIITNVSRQDGGWWRGDY-GAKKQHWFPSNFVEEIE 476

 Score = 30.0 bits (66), Expect = 5.9,   Method: Compositional matrix adjust.
 Identities = 15/54 (27%), Positives = 28/54 (51%)
 Frame = +3

Query: 1219 QALYNYTPRNEDELELRESDVVDVMEKCDDGWFVGTSRRTKFFGTFPGNYVKRL 1272
            +AL++Y    +DEL   +  ++  + + D GW+ G     K    FP N+V+ +
Sbjct: 315  KALHDYNANRDDELSFCKGAIITNVSRQDGGWWRGDYGAKKQHW-FPSNFVEEI 473
>27252
          Length = 378

 Score = 38.5 bits (88), Expect = 0.018,   Method: Compositional matrix adjust.
 Identities = 19/42 (45%), Positives = 28/42 (66%), Gaps = 1/42 (2%)
 Frame = +2

Query: 1053 ELSFKKGDTVYILR-KIDQNWYEGEHHGRVGIFPISYVEKLT 1093
            +L  K+G+T+ +L   ID  W EGE +GR G FP ++VE L+
Sbjct: 170  QLKLKQGETIKVLAINIDGQW-EGEINGRTGKFPFTHVEFLS 292
>26032
          Length = 465

 Score = 37.4 bits (85), Expect = 0.039,   Method: Composition-based stats.
 Identities = 17/48 (35%), Positives = 28/48 (58%)
 Frame = +2

Query: 1045 DFKAQTSKELSFKKGDTVYILRKIDQNWYEGEHHGRVGIFPISYVEKL 1092
            DF+     EL F+K D + ++ + D++ + GE +G  G FP  +VE L
Sbjct: 29   DFERHDDDELGFRKNDIITLISQKDEHCWIGELNGLRGWFPAKFVEVL 172
>38574
          Length = 408

 Score = 33.1 bits (74), Expect(2) = 0.044,   Method: Compositional matrix adjust.
 Identities = 13/30 (43%), Positives = 21/30 (70%)
 Frame = -1

Query: 1242 VMEKCDDGWFVGTSRRTKFFGTFPGNYVKR 1271
            V ++ +DGW+ GT  RT   G FPG++V++
Sbjct: 282  VHKRREDGWYKGTQERTSKTGLFPGSFVEK 193

 Score = 22.7 bits (47), Expect(2) = 0.044,   Method: Compositional matrix adjust.
 Identities = 9/25 (36%), Positives = 15/25 (60%)
 Frame = -2

Query: 1216 EPFQALYNYTPRNEDELELRESDVV 1240
            E ++ +  Y P+ + ELEL   D+V
Sbjct: 359  ERYRCIVPYPPQTDHELELEMGDIV 285

 Score = 30.8 bits (68), Expect = 3.4,   Method: Compositional matrix adjust.
 Identities = 14/36 (38%), Positives = 21/36 (58%)
 Frame = -1

Query: 1132 RKGDRIILLKRVDQNWYEGKIPGTNRQGIFPVSYVE 1167
            R G    + KR +  WY+G    T++ G+FP S+VE
Sbjct: 303  RNGRHSHVHKRREDGWYKGTQERTSKTGLFPGSFVE 196
>31183
          Length = 923

 Score = 36.2 bits (82), Expect = 0.091,   Method: Composition-based stats.
 Identities = 13/31 (41%), Positives = 19/31 (61%)
 Frame = +1

Query: 1060 DTVYILRKIDQNWYEGEHHGRVGIFPISYVE 1090
            D +  +  ID  W+ G  HG+ G+FP +YVE
Sbjct: 4    DVITDIEMIDDGWWRGSCHGKNGLFPANYVE 96

 Score = 31.2 bits (69), Expect = 3.1,   Method: Composition-based stats.
 Identities = 14/33 (42%), Positives = 19/33 (57%)
 Frame = +1

Query: 1238 DVVDVMEKCDDGWFVGTSRRTKFFGTFPGNYVK 1270
            DV+  +E  DDGW+ G+       G FP NYV+
Sbjct: 4    DVITDIEMIDDGWWRGSCHGKN--GLFPANYVE 96
>11228
          Length = 2155

 Score = 34.3 bits (77), Expect = 0.34,   Method: Compositional matrix adjust.
 Identities = 18/45 (40%), Positives = 23/45 (51%)
 Frame = -2

Query: 1228 NEDELELRESDVVDVMEKCDDGWFVGTSRRTKFFGTFPGNYVKRL 1272
            + DEL   + DV  V  + +DGW   T  RTK  G  P  +VK L
Sbjct: 1632 DSDELSFCKGDVFVVQNEMEDGWLWVTCERTKESGLVPAPFVKDL 1498
>13641
          Length = 2081

 Score = 33.9 bits (76), Expect = 0.45,   Method: Compositional matrix adjust.
 Identities = 22/69 (31%), Positives = 38/69 (55%), Gaps = 13/69 (18%)
 Frame = +2

Query: 1030 RGTP--EKEKLPAKAVYDFKAQT-----SKE--LSFKKGDTVYILRKIDQNWYEGEHHG- 1079
            R TP  +K ++  KA++ F ++       KE  LSF++GD ++I+ + D  W++   HG 
Sbjct: 122  RRTPGSKKREMVVKAMFSFNSKLDDNIPCKEAGLSFQQGDILHIVNQEDAIWWQAYKHGD 301

Query: 1080 ---RVGIFP 1085
               R G+ P
Sbjct: 302  AKKRAGLIP 328
>15115
          Length = 443

 Score = 33.5 bits (75), Expect = 0.59,   Method: Composition-based stats.
 Identities = 16/47 (34%), Positives = 27/47 (57%), Gaps = 1/47 (2%)
 Frame = -2

Query: 1047 KAQTSKELSFKKGDTVYILRKIDQNWYEG-EHHGRVGIFPISYVEKL 1092
            +A    E++F   D +  + +ID+ W++G    G  G+FP +YVE L
Sbjct: 430  QAGDDTEITFDPDDIITNIDQIDEGWWQGFAPDGSYGMFPANYVELL 290
>18881
          Length = 762

 Score = 32.3 bits (72), Expect = 1.3,   Method: Composition-based stats.
 Identities = 14/45 (31%), Positives = 29/45 (64%), Gaps = 2/45 (4%)
 Frame = -3

Query: 1125 TNVELSLRKGDRIILLKR--VDQNWYEGKIPGTNRQGIFPVSYVE 1167
            +  +++L+  DRI +L +   D+ W++G+   T + G FP++YV+
Sbjct: 448  STTQVTLKLNDRISILSKNGQDKGWWKGENLRTKKVGYFPLAYVD 314

 Score = 29.6 bits (65), Expect = 8.3,   Method: Composition-based stats.
 Identities = 15/41 (36%), Positives = 24/41 (58%), Gaps = 2/41 (4%)
 Frame = -3

Query: 1231 ELELRESDVVDVMEKC--DDGWFVGTSRRTKFFGTFPGNYV 1269
            ++ L+ +D + ++ K   D GW+ G + RTK  G FP  YV
Sbjct: 439  QVTLKLNDRISILSKNGQDKGWWKGENLRTKKVGYFPLAYV 317
>33143
          Length = 1469

 Score = 32.0 bits (71), Expect = 1.7,   Method: Compositional matrix adjust.
 Identities = 20/73 (27%), Positives = 30/73 (41%), Gaps = 3/73 (4%)
 Frame = -2

Query: 1023 RSASRERRGTPEKEKLPAKAVYDFKAQTSKELSFKKGDTVYIL---RKIDQNWYEGEHHG 1079
            R  + +  G        A AV  + A  S E+S + GD V ++         W+ G+   
Sbjct: 481  RMLALDHSGINTPAIAAAHAVKPYAAHASDEISLQVGDFVSVIDMPSSEGTKWWRGKKGF 302

Query: 1080 RVGIFPISYVEKL 1092
             VG FP   VE +
Sbjct: 301  EVGFFPADCVEVI 263
>02941
          Length = 1262

 Score = 29.6 bits (65), Expect = 7.1,   Method: Composition-based stats.
 Identities = 11/35 (31%), Positives = 21/35 (60%)
 Frame = -3

Query: 506  CCNAYRQHLDVPGDSQRAITFKNGWQMARQNAEIW 540
            CC A+  + ++ G  Q A++FK  W   R ++++W
Sbjct: 1113 CCIAFFNN*NLLGQEQVAVSFKLRWPGVRTSSQLW 1009
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|13384870|ref|NP_079736.1| transmembrane protein 126A
[Mus musculus]
         (196 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

02846                                                                  64   4e-11
11641                                                                  28   2.4  
04426                                                                  28   2.8  
01645                                                                  27   4.5  
01056                                                                  27   5.6  
>02846
          Length = 1175

 Score = 63.9 bits (154), Expect = 4e-11,   Method: Compositional matrix adjust.
 Identities = 39/126 (30%), Positives = 68/126 (53%), Gaps = 1/126 (0%)
 Frame = -2

Query: 9    SKDDLILNIISRKIKQLPESDRNLLEYGSAYIGLNAAFGGLIANSLFRRILNVTQ-ARLA 67
            ++++++    S  +K  P S+     +GS  +G  AA  G++ N++ R+ L V    RLA
Sbjct: 1117 TEEEVLHMQWSTILKWKPYSEMLPFTWGSGIVGGVAALSGVVINNILRQRLGVMHFGRLA 938

Query: 68   SSLPMAVIPFLTANLSYQSLVSLPLSTGDLNCETCTTTRGALVGLVMGGLYPILLAIPVN 127
            +  P AV+P  T+ L ++ +V+  +  GD  C  C   R   V  + GGLYP++L  P++
Sbjct: 937  TYAPTAVLPVFTSILLHKFMVTDKILQGDFPCTVCAAVRSGSVQSLSGGLYPMVLG-PIS 761

Query: 128  GGLAAR 133
              + AR
Sbjct: 760  CIIIAR 743
>11641
          Length = 2509

 Score = 28.1 bits (61), Expect = 2.4,   Method: Compositional matrix adjust.
 Identities = 16/43 (37%), Positives = 24/43 (55%)
 Frame = -1

Query: 130  LAARYESSPLPQRGNIFNYWITVSKPVFRKMLFPTLLQTVFAS 172
             AA+ E   + +R NIF+    + KPV R + +P LL  +F S
Sbjct: 2419 FAAKVEE--MRRRTNIFDVEAMLIKPVQRILKYPLLLNELFKS 2297
>04426
          Length = 1103

 Score = 27.7 bits (60), Expect = 2.8,   Method: Compositional matrix adjust.
 Identities = 14/35 (40%), Positives = 16/35 (45%)
 Frame = +3

Query: 143 GNIFNYWITVSKPVFRKMLFPTLLQTVFASYLGSR 177
           G+   YW TVS PVF    +  L   V     GSR
Sbjct: 879 GDWHPYW*TVSTPVFPTFFYNNLFMCVVCVCEGSR 983
>01645
          Length = 1116

 Score = 27.3 bits (59), Expect = 4.5,   Method: Compositional matrix adjust.
 Identities = 13/22 (59%), Positives = 16/22 (72%), Gaps = 1/22 (4%)
 Frame = +2

Query: 90   LPLSTG-DLNCETCTTTRGALV 110
            LP+STG  LNC  C  TRG+L+
Sbjct: 980  LPISTGLRLNCPDCKATRGSLL 1045
>01056
          Length = 1657

 Score = 26.9 bits (58), Expect = 5.6,   Method: Compositional matrix adjust.
 Identities = 20/71 (28%), Positives = 29/71 (40%), Gaps = 8/71 (11%)
 Frame = -3

Query: 85   QSLVSLPLSTGDLNCETCTT---TRGALVGLVMGGLYPILLAIPVNG-----GLAARYES 136
            +S V +  ++GDL C  CT       A   L  GG+Y +  +  VN      G AA   +
Sbjct: 1502 KSPVMMMKASGDLTCRLCTCWAMVSAACEALAEGGMYAVHTSTCVNSRGR**GRAASVSN 1323

Query: 137  SPLPQRGNIFN 147
            S   +    F 
Sbjct: 1322 STHGEHSXCFT 1290
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|21735425|ref|NP_080223.1| dynein light chain
roadblock-type 1 [Mus musculus]
         (96 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

02412                                                                  63   4e-11
20764                                                                  26   4.6  
>02412
          Length = 2454

 Score = 62.8 bits (151), Expect = 4e-11,   Method: Compositional matrix adjust.
 Identities = 26/41 (63%), Positives = 35/41 (85%)
 Frame = -2

Query: 55   STVREIDPQNDLTFLRIRSKKNEIMVAPDKDYFLIVIQNPT 95
            +TVRE+D  NDLTFLR+RSKK+EIM AP+ +Y ++VIQ P+
Sbjct: 2453 NTVRELDSTNDLTFLRLRSKKHEIMCAPENEYMMVVIQTPS 2331
>20764
          Length = 738

 Score = 25.8 bits (55), Expect = 4.6,   Method: Compositional matrix adjust.
 Identities = 11/37 (29%), Positives = 24/37 (64%)
 Frame = +3

Query: 33  TMDNPTTTQYANLMHNFILKARSTVREIDPQNDLTFL 69
           T++   +TQ +  + +F + ARS ++ I+P+  L+F+
Sbjct: 300 TVERIASTQRS**IISFTVPARSQLKSIEPRTSLSFV 410
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|13385010|ref|NP_079845.1| microsomal glutathione
S-transferase 3 [Mus musculus]
         (153 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

01563                                                                  63   5e-11
34733                                                                  30   0.58 
05814                                                                  28   1.9  
17224                                                                  27   2.5  
17782                                                                  24   4.1  
06104                                                                  25   8.8  
>01563
          Length = 2720

 Score = 62.8 bits (151), Expect = 5e-11,   Method: Compositional matrix adjust.
 Identities = 29/54 (53%), Positives = 38/54 (70%)
 Frame = +2

Query: 88  GLGLAWIIGRVLYAYGYYTGDPSKRYRGAVGSLALFALMGTTVCSAFQHLGWIR 141
           G G  +++ RVLYA GYYTGDPSKR RGA G++A+  ++ TT   A + LGW R
Sbjct: 2   GAGAVYLLSRVLYALGYYTGDPSKRMRGAFGNMAVLGMLATTARIAVRQLGWSR 163
>34733
          Length = 599

 Score = 29.6 bits (65), Expect = 0.58,   Method: Compositional matrix adjust.
 Identities = 18/69 (26%), Positives = 34/69 (49%), Gaps = 1/69 (1%)
 Frame = +1

Query: 2   AVLSKEYGFVLLTGAASFVMVLHL-AINVGKARKKYKVEYPVMYSTDPENGHMFNCIQRA 60
           A+  K YG V ++ + +   +L L A++V + R   KVE  +  S   ++ H   C+Q+ 
Sbjct: 115 AICDKTYGIVWVSLSXTLQALL*LFAVSVLRTR*-AKVEVGIAVSNPSQSQHRLQCVQQD 291

Query: 61  HQNTLEVYP 69
            +    + P
Sbjct: 292 REKRSRIAP 318
>05814
          Length = 1242

 Score = 27.7 bits (60), Expect = 1.9,   Method: Compositional matrix adjust.
 Identities = 17/36 (47%), Positives = 21/36 (58%)
 Frame = -3

Query: 110 SKRYRGAVGSLALFALMGTTVCSAFQHLGWIRPGLG 145
           S R     GSLAL  ++G   CSA ++L  IR GLG
Sbjct: 865 SVRKMDEAGSLALILVLGP--CSAGKNLECIRAGLG 764
>17224
          Length = 490

 Score = 27.3 bits (59), Expect = 2.5,   Method: Compositional matrix adjust.
 Identities = 10/27 (37%), Positives = 16/27 (59%)
 Frame = +1

Query: 126 MGTTVCSAFQHLGWIRPGLGYGSRSCH 152
           + + +   F+ L W R GLG+  +SCH
Sbjct: 136 IASPIAQWFRRLLWDRRGLGFDLQSCH 216
>17782
          Length = 1021

 Score = 23.9 bits (50), Expect(2) = 4.1,   Method: Compositional matrix adjust.
 Identities = 10/24 (41%), Positives = 14/24 (58%), Gaps = 7/24 (29%)
 Frame = +3

Query: 48  PENGHMFNCI-------QRAHQNT 64
           PENGH++N +       Q AHQ +
Sbjct: 378 PENGHLYNVVEHRKLYTQSAHQTS 449

 Score = 20.8 bits (42), Expect(2) = 4.1,   Method: Compositional matrix adjust.
 Identities = 7/11 (63%), Positives = 7/11 (63%)
 Frame = +2

Query: 46  TDPENGHMFNC 56
           T PENGH   C
Sbjct: 263 TSPENGHFVQC 295
>06104
          Length = 1002

 Score = 25.4 bits (54), Expect = 8.8,   Method: Compositional matrix adjust.
 Identities = 10/29 (34%), Positives = 17/29 (58%)
 Frame = +2

Query: 34  KKYKVEYPVMYSTDPENGHMFNCIQRAHQ 62
           K +   +P+ Y   PENG +F+C+ R  +
Sbjct: 923 KVFNASFPLSY---PENGPLFSCMNRPTR 1000
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6679975|ref|NP_032132.1| opsin 1 (cone pigments),
medium-wave-sensitive (color blindness, deutan) [Mus musculus]
         (359 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

35147                                                                  65   6e-11
05928                                                                  51   8e-07
26971                                                                  45   4e-05
38474                                                                  43   2e-04
26601                                                                  42   4e-04
27862                                                                  41   7e-04
15025                                                                  38   0.006
05362                                                                  37   0.009
>35147
          Length = 670

 Score = 64.7 bits (156), Expect = 6e-11,   Method: Compositional matrix adjust.
 Identities = 59/203 (29%), Positives = 98/203 (48%), Gaps = 7/203 (3%)
 Frame = +1

Query: 62  SVFTNGLVLAATMRFKKLRHPLNWILVNLAVADLAETIIASTISVVNQIYGYFVLGHP-- 119
           +V  N +VL   +R + +R   N  LVNLAVADL         ++   I G +V G+P  
Sbjct: 70  AVVGNSMVLTVVIRHRGMRTRTNLFLVNLAVADLLVGATVVPFAITTIIEGRWVFGNPNG 249

Query: 120 -LCVIEGYIVSLCGITGLWSLAIISWERWLVVCKPFGNVRFDAKLATVGIVFSWVWAAIW 178
             C I G++   C +  + +L  IS  +   + +P G+  F  +     +  +WVWAA+ 
Sbjct: 250 VFCTINGWLNCFCLVASIHTLMYISVHKHYSITQPLGS-HFKLRQILGMMAAAWVWAAVS 426

Query: 179 TAPPIFGWSRYWPYGLKTSCGPDVFSGTSYP-GVQSYMM--VLMVTCCIFPLSIIVLCYL 235
           +   + G S        + CGP+      YP G++SY+   ++  T  + P+ I+  CY 
Sbjct: 427 STITVTGLSSVRYKEGTSQCGPE------YPDGLKSYIFHGIIQFTNILIPVIILTYCYA 588

Query: 236 QVWLAIRAVAKQ-QKESESTQKA 257
           +++  IRA  K+ Q+ S   Q A
Sbjct: 589 RMFQEIRAHTKRLQRNSTLEQDA 657
>05928
          Length = 1549

 Score = 50.8 bits (120), Expect = 8e-07,   Method: Compositional matrix adjust.
 Identities = 70/331 (21%), Positives = 133/331 (40%), Gaps = 22/331 (6%)
 Frame = -3

Query: 18   THASIFTYTNSNSTKGPFEGPNYHIAPRWVYHLTSTWMILVVVASVFTNGLVLAATMRFK 77
            T  S+  + N N T+      +Y +  + +  +    +  + + +   N LV       K
Sbjct: 1433 TRGSLINFINGNQTES---KEHYSVLLKQL--VIGVVLSCMALLAFMGNLLVCIVIFTDK 1269

Query: 78   KLRHPLNW-ILVNLAVADLAETIIASTISVVNQIYGYFVLGHPLCVIEGYIVSLCGITGL 136
            ++++  ++    +LA AD+   ++  + ++VN + G+++ G   C+I   +  +C    +
Sbjct: 1268 QMKNKKSYYFFFSLAAADMLVVVMVMSFAIVNDVLGHWLFGLRFCLIWVSLDIMCSTASI 1089

Query: 137  WSLAIISWERWLVVCKPFG-NVRFDAKLATVGIVFSWVWA-AIWTAPPIFGW-----SRY 189
             SL +I  +R+  +  P    +R   K     I   WV +  I   P   GW     +  
Sbjct: 1088 LSLCLICIDRFCQIQYPLQYELRLSVKRIVFLIFLVWVISICIAFIPLQLGWHLPPLNER 909

Query: 190  WPYGLKTSCGPDVFSGTSYPGVQSYMMVLMVTCCIFPLSIIVLCYL-------------- 235
             P    + C  D+     Y  V S +   +   C+  +SI +  YL              
Sbjct: 908  APID-DSFCVLDI--SFEYALVSSSISFYIP--CVIMVSIYLKIYLLANKHFKNIIRSQV 744

Query: 236  QVWLAIRAVAKQQKESESTQKAEKEVTRMVVVMVFAYCLCWGPYTFFACFATAHPGYAFH 295
             V L  + +  QQK S S  KA   +     +++  + +CW P+ F      A       
Sbjct: 743  HVRLETQKLGGQQKTSISHHKAAITIG----ILMGVFLVCWLPF-FIVNPIAAKCAACVP 579

Query: 296  PLVASLPSYFAKSATIYNPIIYVFMNRQFRN 326
            P++  + ++   + +  NPIIY   N  FRN
Sbjct: 578  PILFVIFTWMGYANSCLNPIIYSLFNSDFRN 486
>26971
          Length = 467

 Score = 45.1 bits (105), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 42/147 (28%), Positives = 64/147 (43%), Gaps = 7/147 (4%)
 Frame = -1

Query: 60  VASVFTNGLVLAATMRFKKLRHPLNWILVNLAVADLA------ETIIASTISVVNQIYGY 113
           + +V  N LVL A  + + LR   N  + +LA AD+        ++I S + +    YG 
Sbjct: 455 ILTVMGNTLVLLAIAKTRSLRTVTNCFIGSLAAADVMVGLFIPPSVILSYVGLPRDFYG- 279

Query: 114 FVLGHPLCVIEGYIVSLCGITGLWSLAIISWERWLVVCKPFGNVR-FDAKLATVGIVFSW 172
                  CV+   +V L     L+SL  ++ ER+L V  PF   R      A V +V +W
Sbjct: 278 -------CVLVNTMVVLITNISLFSLLAVALERFLAVKHPFLYQRVMTINRALVVVVITW 120

Query: 173 VWAAIWTAPPIFGWSRYWPYGLKTSCG 199
           V A +    P  GW+     G   +C 
Sbjct: 119 VLAIVIGLIPTMGWN-LGKEGFDNTCA 42
>38474
          Length = 550

 Score = 43.1 bits (100), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 31/118 (26%), Positives = 52/118 (44%), Gaps = 11/118 (9%)
 Frame = +3

Query: 224 IFPLSIIVLCYLQVWLAIRAVAKQQKESESTQKA--------EKEVTRMVVVMVFAYCLC 275
           I P +II  CY  V  A++  +K +  S +  +         +K   +M++ MV  +  C
Sbjct: 171 IVPCTIITFCYSMVSRALKKRSKVKIGSGARSREREEQEIRRKKRTNKMLIAMVIIFMCC 350

Query: 276 WGPYT---FFACFATAHPGYAFHPLVASLPSYFAKSATIYNPIIYVFMNRQFRNCILH 330
           W P         +  +   + +  LV  +    A S+TIYNP +Y +MN  F+    H
Sbjct: 351 WMPLNVSLLVREYQDSVEHWYYFTLVFFIAHVIAMSSTIYNPFLYAWMNDNFKKSSNH 524
>26601
          Length = 397

 Score = 42.0 bits (97), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 22/99 (22%), Positives = 54/99 (54%)
 Frame = -2

Query: 55  MILVVVASVFTNGLVLAATMRFKKLRHPLNWILVNLAVADLAETIIASTISVVNQIYGYF 114
           ++ ++V++V  N  V+ + +  +K    +++ ++ LA++DL   I A   ++V+     +
Sbjct: 303 LLAIIVSAVVMNSFVIWSFIVRRKTVVSVDYYILTLAISDLCSPIFAYPFAMVSTFSHGW 124

Query: 115 VLGHPLCVIEGYIVSLCGITGLWSLAIISWERWLVVCKP 153
           + G   C++ G++    GI  ++ L+ +   R++ VC P
Sbjct: 123 IFGETGCLVNGFLGFFFGIVDIFILSTLGITRYICVCHP 7
>27862
          Length = 371

 Score = 41.2 bits (95), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 28/100 (28%), Positives = 53/100 (53%), Gaps = 2/100 (2%)
 Frame = +3

Query: 37  GPNYHIAPRWVYHLTSTWMILVVVASVFTNGLVLAATMRFKKLRHPLNWILVNLAVADLA 96
           GP     P  VY +T+  ++LV + ++  N + + A +  +KLR   N  +V+LA+ADL 
Sbjct: 51  GPPPQYGPAGVYGVTAV-LLLVPLLTIVGNSVTILAVLTHRKLRTKTNAFIVSLAIADLC 227

Query: 97  ETIIASTISVVNQIYGYF-VLGHPLCVIEG-YIVSLCGIT 134
            +++    ++  Q+     +LG  LC +   + V +C +T
Sbjct: 228 VSLLVMPFAIYQQLNNKVWLLGDLLCRLSASFDVMMCTVT 347
>15025
          Length = 449

 Score = 38.1 bits (87), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 22/76 (28%), Positives = 38/76 (50%)
 Frame = +1

Query: 258 EKEVTRMVVVMVFAYCLCWGPYTFFACFATAHPGYAFHPLVASLPSYFAKSATIYNPIIY 317
           ++   ++++  +  + LCW PY   + FA A  G       + +P+  AKS +  NPI Y
Sbjct: 46  QERSVKIILTTMVVFMLCWTPYALMS-FA-ASLGTEIGVGASVIPTIMAKSHSAINPIAY 219

Query: 318 VFMNRQFRNCILHLFG 333
               +++R  I  LFG
Sbjct: 220 FVCFKKYRLSIRQLFG 267
>05362
          Length = 1201

 Score = 37.4 bits (85), Expect = 0.009,   Method: Compositional matrix adjust.
 Identities = 32/102 (31%), Positives = 45/102 (44%), Gaps = 12/102 (11%)
 Frame = -3

Query: 245 AKQQKESES-----TQKAEKEV--TRMVVVMVFAYCLCWGPYTFFACFATAHPGYAFHPL 297
           AK Q E  +     T  A K+V   R + + VFA+   W PYT     ATA   +    +
Sbjct: 548 AKNQHEQSTSAANFTNSARKDVKAARALFIFVFAFVFLWAPYT----MATAIVAFCEDCV 381

Query: 298 VASLPSYFA-----KSATIYNPIIYVFMNRQFRNCILHLFGK 334
            A +  +F      KSA   NP +Y   N +F+   L + GK
Sbjct: 380 DADVYEFFVWLLWIKSAV--NPFLYSANNARFKMNFLKILGK 261
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6753820|ref|NP_034308.1| FUS interacting protein
(serine-arginine rich) 1 isoform 1 [Mus musculus]
         (183 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

02347                                                                  63   8e-11
12506                                                                  62   2e-10
30672                                                                  59   9e-10
20169                                                                  59   9e-10
02809                                                                  55   1e-08
17775                                                                  55   2e-08
02140                                                                  54   4e-08
16427                                                                  54   4e-08
00302                                                                  54   5e-08
23720                                                                  50   6e-07
04988                                                                  50   6e-07
17681                                                                  49   8e-07
01278                                                                  46   8e-06
12350                                                                  45   1e-05
29364                                                                  45   1e-05
15503                                                                  45   2e-05
23322                                                                  45   2e-05
03000                                                                  44   3e-05
19868                                                                  44   4e-05
01065                                                                  44   4e-05
32386                                                                  44   5e-05
00738                                                                  44   5e-05
31618                                                                  44   6e-05
00029                                                                  43   8e-05
11019                                                                  42   2e-04
28652                                                                  42   2e-04
11126                                                                  42   2e-04
31310                                                                  41   3e-04
11579                                                                  41   3e-04
30934                                                                  40   6e-04
33516                                                                  39   0.001
25950                                                                  38   0.002
03059                                                                  37   0.003
28455                                                                  35   0.019
14123                                                                  35   0.021
22492                                                                  30   0.63 
03903                                                                  30   0.67 
28605                                                                  28   2.0  
36728                                                                  27   3.7  
01513                                                                  26   8.8  
>02347
          Length = 928

 Score = 62.8 bits (151), Expect = 8e-11,   Method: Compositional matrix adjust.
 Identities = 31/88 (35%), Positives = 51/88 (57%)
 Frame = -3

Query: 1   MSRYLRPPNTSLFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFED 60
           MSRY       ++V ++  D   +++ R F  YG + +V+V      R P GFA+V+FED
Sbjct: 773 MSRYGSSVEGKIYVGDLPPDASEKEVERAFNYYGHLRNVWV-----ARNPPGFAFVEFED 609

Query: 61  VRDAEDALHNLDRKWICGRQIEIQFAQG 88
            RDA+DA+  LD   +CG ++ ++ + G
Sbjct: 608 TRDADDAVRALDGTVVCGNRVRVEHSTG 525
>12506
          Length = 1056

 Score = 61.6 bits (148), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 34/93 (36%), Positives = 49/93 (52%)
 Frame = -3

Query: 11   SLFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFEDVRDAEDALHN 70
            SLF     DD     L   F  +G IVD+ +PLD+ T + RGFA+++FE   DA  A+ N
Sbjct: 1051 SLFTAGEVDDKV---LHAAFLPFGDIVDIQIPLDYETEKHRGFAFIEFELAEDAAAAIDN 881

Query: 71   LDRKWICGRQIEIQFAQGDRKTPNQMKAKEGRN 103
            ++   + GR I +  A+        MK KEG +
Sbjct: 880  MNESELFGRTIRVNLAK-------PMKVKEGAS 803
>30672
          Length = 877

 Score = 59.3 bits (142), Expect = 9e-10,   Method: Compositional matrix adjust.
 Identities = 27/75 (36%), Positives = 46/75 (61%)
 Frame = +3

Query: 12  LFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFEDVRDAEDALHNL 71
           L +RN+A   +  D+R  FG++G I +V +PL     R RGFA+VQF +V+ A+ A+ ++
Sbjct: 411 LIIRNLAFKCKEADIRSHFGKFGTISEVTIPLK-QGDRSRGFAFVQFTEVKAAQKAISDM 587

Query: 72  DRKWICGRQIEIQFA 86
           +   I  R + + +A
Sbjct: 588 NGTAIMDRPVAVDWA 632

 Score = 48.9 bits (115), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 34/92 (36%), Positives = 47/92 (51%), Gaps = 1/92 (1%)
 Frame = +3

Query: 11  SLFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFEDVRDAEDALHN 70
           +LFVRN+  +T +E L   F + GP+   +V       + RGF YVQF  +   EDA+  
Sbjct: 15  TLFVRNLPFETSNEKLLEAFEQVGPLKTAFVVAGKEPGKCRGFGYVQFSML---EDAIKA 185

Query: 71  LDRKWIC-GRQIEIQFAQGDRKTPNQMKAKEG 101
            D    C GR+I + FA  D K   + K K G
Sbjct: 186 KDTVTHCSGRKISLSFA--DTKKSWKTKQKGG 275
>20169
          Length = 1364

 Score = 59.3 bits (142), Expect = 9e-10,   Method: Compositional matrix adjust.
 Identities = 29/78 (37%), Positives = 47/78 (60%)
 Frame = -1

Query: 9    NTSLFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFEDVRDAEDAL 68
            +  ++V  +      ++L  +F +YGP+ +V+V      RRP GFA+V+FED RDAEDA+
Sbjct: 1073 DCKVYVGELGHGCAKQELEDKFAKYGPLKNVWV-----ARRPAGFAFVEFEDNRDAEDAV 909

Query: 69   HNLDRKWICGRQIEIQFA 86
              LD   I GR+  ++ +
Sbjct: 908  QALDGARINGRRARVEMS 855
>02809
          Length = 1475

 Score = 55.5 bits (132), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 26/64 (40%), Positives = 40/64 (62%)
 Frame = -1

Query: 9    NTSLFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFEDVRDAEDAL 68
            +  ++V  +      ++L  +F +YGP+ +V+V      RRP GFA+V+FED RDAEDA+
Sbjct: 1337 DCKVYVGELGHGCAKQELEDKFAKYGPLKNVWV-----ARRPAGFAFVEFEDNRDAEDAV 1173

Query: 69   HNLD 72
              LD
Sbjct: 1172 QALD 1161
>17775
          Length = 1282

 Score = 54.7 bits (130), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 30/82 (36%), Positives = 44/82 (53%)
 Frame = -2

Query: 8    PNTSLFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFEDVRDAEDA 67
            P  SL+V ++  D     L  +F   GP++ + V  D  TRR  G+AYV F+   DAE A
Sbjct: 1200 PMASLYVGDLHPDVTEAMLFEKFSTAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERA 1021

Query: 68   LHNLDRKWICGRQIEIQFAQGD 89
            L  ++   + GR I I ++Q D
Sbjct: 1020 LDTMNFDTVKGRPIRIMWSQRD 955

 Score = 29.3 bits (64), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 12/33 (36%), Positives = 19/33 (57%)
 Frame = -2

Query: 49  RPRGFAYVQFEDVRDAEDALHNLDRKWICGRQI 81
           + RGF +V FE+   AE A+  ++   + GR I
Sbjct: 537 KSRGFGFVSFEEPEGAEKAVDEINGTEVSGRII 439
>02140
          Length = 1796

 Score = 53.9 bits (128), Expect = 4e-08,   Method: Compositional matrix adjust.
 Identities = 29/82 (35%), Positives = 42/82 (51%)
 Frame = +3

Query: 6   RPPNTSLFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFEDVRDAE 65
           +PP+  LFV  +   T  EDL   F R+GPI    V  D  T+    +A+V+FE     E
Sbjct: 789 KPPDNVLFVCKLNPVTTDEDLEMIFSRFGPITSCEVIRDHKTKESLQYAFVEFEKPEHCE 968

Query: 66  DALHNLDRKWICGRQIEIQFAQ 87
           +A   +D   I  R+I + F+Q
Sbjct: 969 NAYFKMDNVLIDDRRIHVDFSQ 1034
>16427
          Length = 1313

 Score = 53.9 bits (128), Expect = 4e-08,   Method: Compositional matrix adjust.
 Identities = 26/75 (34%), Positives = 46/75 (61%)
 Frame = +1

Query: 12  LFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFEDVRDAEDALHNL 71
           LFV  +A++   + L REF ++G I +  V  D   +  RGF +V +E+  DAE+A+ ++
Sbjct: 142 LFVGGLAEEIDEKVLEREFSKFGRITESMVIRDKVRQVSRGFGFVTYENPMDAEEAVKHM 321

Query: 72  DRKWICGRQIEIQFA 86
           D K I G+++ ++ A
Sbjct: 322 DGKEILGKKLHVEDA 366
>00302
          Length = 927

 Score = 53.5 bits (127), Expect = 5e-08,   Method: Compositional matrix adjust.
 Identities = 32/83 (38%), Positives = 45/83 (54%)
 Frame = -1

Query: 8   PNTSLFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFEDVRDAEDA 67
           PN  L +  ++  T+   LR  FGRYG I +V V  D  T R RGFA+V F+   DA +A
Sbjct: 471 PNRCLGIFGLSLYTQERGLREVFGRYGHISEVQVVYDRQTGRSRGFAFVYFKSSEDAHEA 292

Query: 68  LHNLDRKWICGRQIEIQFAQGDR 90
               +   I GR+I + F+  +R
Sbjct: 291 KDRCNGIEIDGRKIRVDFSITER 223
>23720
          Length = 739

 Score = 49.7 bits (117), Expect = 6e-07,   Method: Compositional matrix adjust.
 Identities = 25/80 (31%), Positives = 46/80 (57%)
 Frame = -1

Query: 9   NTSLFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFEDVRDAEDAL 68
            T +++  +    R +D+ R F  YG + D+ +          G+ +V+FED RDA+DA+
Sbjct: 688 GTRVYIGRLPYQAREKDIERFFRGYGRVNDIMLK--------NGYGFVEFEDFRDADDAV 533

Query: 69  HNLDRKWICGRQIEIQFAQG 88
           + L+ K +CG ++ I+ A+G
Sbjct: 532 YELNGKDLCGERVIIEHARG 473
>04988
          Length = 705

 Score = 49.7 bits (117), Expect = 6e-07,   Method: Compositional matrix adjust.
 Identities = 25/80 (31%), Positives = 46/80 (57%)
 Frame = -3

Query: 9   NTSLFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFEDVRDAEDAL 68
            T +++  +    R +D+ R F  YG + D+ +          G+ +V+FED RDA+DA+
Sbjct: 655 GTRVYIGRLPYQAREKDIERFFRGYGRVNDIMLK--------NGYGFVEFEDFRDADDAV 500

Query: 69  HNLDRKWICGRQIEIQFAQG 88
           + L+ K +CG ++ I+ A+G
Sbjct: 499 YELNGKDLCGERVIIEHARG 440
>17681
          Length = 964

 Score = 49.3 bits (116), Expect = 8e-07,   Method: Compositional matrix adjust.
 Identities = 24/82 (29%), Positives = 45/82 (54%)
 Frame = +2

Query: 12  LFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFEDVRDAEDALHNL 71
           +FV +++ +  +E LR  F  +G I +  +  D  T + +G+A+V F    +AE+A+  +
Sbjct: 38  IFVGDLSPEIETETLREAFAPFGEISNCRIVRDPQTMKSKGYAFVSFVKKAEAENAIQAM 217

Query: 72  DRKWICGRQIEIQFAQGDRKTP 93
           + +WI  R I   ++   RK P
Sbjct: 218 NGQWIGSRSIRTNWS--TRKLP 277
>01278
          Length = 1082

 Score = 46.2 bits (108), Expect = 8e-06,   Method: Compositional matrix adjust.
 Identities = 21/61 (34%), Positives = 36/61 (59%)
 Frame = +2

Query: 11  SLFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFEDVRDAEDALHN 70
           ++ V N+++DTR  DL+  F  +GPI  +Y+  D  T + +GFA++ F    DA  A+  
Sbjct: 638 TIRVTNLSEDTRESDLQELFRPFGPISRIYLAKDKVTGQSKGFAFINFHRREDASRAIAG 817

Query: 71  L 71
           +
Sbjct: 818 V 820
>12350
          Length = 975

 Score = 45.4 bits (106), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 28/78 (35%), Positives = 42/78 (53%)
 Frame = -2

Query: 9   NTSLFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFEDVRDAEDAL 68
           N  +FV    DD  ++DLR+ F ++G +VDV++P  F     R FA+V F D   A+ +L
Sbjct: 365 NRKIFVGRCTDDMTADDLRQFFSKFGEVVDVFIPRPF-----RAFAFVSFADPEVAQ-SL 204

Query: 69  HNLDRKWICGRQIEIQFA 86
           +  D   I G  + I  A
Sbjct: 203 YGEDH-IIKGASVHISGA 153

 Score = 33.1 bits (74), Expect = 0.065,   Method: Compositional matrix adjust.
 Identities = 17/69 (24%), Positives = 34/69 (49%), Gaps = 3/69 (4%)
 Frame = -2

Query: 10  TSLFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFEDVRDAEDAL- 68
           + L V  +   +  +DLR  F ++G ++ V V  D  T + +GF +++F +       + 
Sbjct: 620 SDLIVLGLPWKSTEDDLRSYFSQFGDLLMVQVKKDPKTGQSKGFGFIRFAEYESQLKCMA 441

Query: 69  --HNLDRKW 75
             H +D +W
Sbjct: 440 QRHMIDGRW 414
>29364
          Length = 1126

 Score = 45.1 bits (105), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 24/74 (32%), Positives = 40/74 (54%)
 Frame = +1

Query: 21 TRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFEDVRDAEDALHNLDRKWICGRQ 80
           R  DL R F  YG   D+ +          G+ +V+FED RDA+DA++ L+ K + G +
Sbjct: 1  VRERDLERFFKGYGRTRDILIK--------NGYGFVEFEDYRDADDAVYELNGKELLGER 156

Query: 81 IEIQFAQGDRKTPN 94
          + ++ A+G  +  N
Sbjct: 157VVVEPARGTARGSN 198
>15503
          Length = 570

 Score = 45.1 bits (105), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 27/86 (31%), Positives = 46/86 (53%), Gaps = 2/86 (2%)
 Frame = +1

Query: 7   PP--NTSLFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFEDVRDA 64
           PP  N  L+V+N+     +E++   FG+YG I  + V     T   +G A+V +ED+ DA
Sbjct: 133 PPEVNRVLYVKNLPYKITAEEMYDIFGKYGAIRQIRVG---NTPETKGTAFVVYEDIFDA 303

Query: 65  EDALHNLDRKWICGRQIEIQFAQGDR 90
           ++A  +L    +C R + + + Q  R
Sbjct: 304 KNACDHLSGFNVCNRYLVVLYYQSTR 381
>23322
          Length = 471

 Score = 44.7 bits (104), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 27/76 (35%), Positives = 40/76 (52%)
 Frame = -2

Query: 12  LFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFEDVRDAEDALHNL 71
           +FV  V +DT  + +R  F  +G I  V +  D  T + RGF +V F D  D+ D     
Sbjct: 404 MFVGGVKEDTTEDMIRDTFNEFGEITGVDLIQDKGTGKNRGFCFVTFGD-HDSVDKAVLK 228

Query: 72  DRKWICGRQIEIQFAQ 87
            R  + GRQ+E++ AQ
Sbjct: 227 KRHDLNGRQVEVKKAQ 180
>03000
          Length = 778

 Score = 43.9 bits (102), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 27/76 (35%), Positives = 40/76 (52%)
 Frame = +3

Query: 12  LFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFEDVRDAEDALHNL 71
           +FV  V +DT  + +R  F  +G I  V +  D  T + RGF +V F D  D+ D     
Sbjct: 366 MFVGGVKEDTTEDMIRDTFNEFGEITGVDLIQDKGTGKNRGFCFVTFGD-HDSVDKAVLK 542

Query: 72  DRKWICGRQIEIQFAQ 87
            R  + GRQ+E++ AQ
Sbjct: 543 KRHDLNGRQVEVKKAQ 590

 Score = 42.7 bits (99), Expect = 9e-05,   Method: Compositional matrix adjust.
 Identities = 24/75 (32%), Positives = 41/75 (54%)
 Frame = +3

Query: 12  LFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFEDVRDAEDALHNL 71
           LF+  ++ +T  + LR  F  +G IVD  V  D  ++R RGF ++ ++D    + A  N 
Sbjct: 93  LFIGGLSYETDEDSLRSHFETWGEIVDCIVMRDSNSKRSRGFGFITYKDAESIDQAQANR 272

Query: 72  DRKWICGRQIEIQFA 86
             K I GR+++ + A
Sbjct: 273 PHK-IDGREVDTKRA 314
>19868
          Length = 434

 Score = 43.9 bits (102), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 26/69 (37%), Positives = 35/69 (50%), Gaps = 4/69 (5%)
 Frame = +2

Query: 12 LFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFEDVRDAEDAL--- 68
          +FV  ++  T  E LR  F ++G I +V V  D  TRR RGF ++ F D    +  L   
Sbjct: 5  MFVGGLSWQTSPESLRDYFNKFGEITEVMVMKDPTTRRSRGFGFITFGDPASVDKVLAQA 184

Query: 69 -HNLDRKWI 76
           H LD K I
Sbjct: 185THELDGKKI 211

 Score = 36.2 bits (82), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 18/53 (33%), Positives = 28/53 (52%)
 Frame = +2

Query: 12  LFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFEDVRDA 64
           +FV  ++  T  ED++  F ++GPI D  +  D  T R RGF +V     R +
Sbjct: 272 IFVGGLSAPTTLEDVKNYFEQFGPIEDAMLMFDKQTNRHRGFGFVTISKRRHS 430
>01065
          Length = 1033

 Score = 43.9 bits (102), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 22/79 (27%), Positives = 44/79 (55%)
 Frame = +2

Query: 9  NTSLFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFEDVRDAEDAL 68
           T + V +++  T + ++R EF R+G I+D+++P    T      A+V +    DAE A+
Sbjct: 11 GTRIHVGSLSSSTSTREIREEFKRFGDIIDLWMPRTQPT-----IAFVVYRYEEDAEKAI 175

Query: 69 HNLDRKWICGRQIEIQFAQ 87
            +D + + GR++ +  A+
Sbjct: 176RRMDGESMHGRRVRVSLAR 232
>32386
          Length = 674

 Score = 43.5 bits (101), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 24/75 (32%), Positives = 41/75 (54%)
 Frame = +1

Query: 12  LFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFEDVRDAEDALHNL 71
           LF+  ++ +T  + LR  F  +G IVD  V  D  ++R RGF ++ ++D    + A  N 
Sbjct: 307 LFIGGLSYETDEDSLRSHFETWGEIVDCIVMRDSNSKRSRGFGFITYKDAESIDQAQANR 486

Query: 72  DRKWICGRQIEIQFA 86
             K I GR+++ + A
Sbjct: 487 PHK-IDGREVDTKRA 528
>00738
          Length = 1559

 Score = 43.5 bits (101), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 22/79 (27%), Positives = 44/79 (55%)
 Frame = -2

Query: 9    NTSLFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFEDVRDAEDAL 68
             T + V +++  T + ++R EF R+G I+D+++P    T      A+V +    DAE A+
Sbjct: 1270 GTRIHVGSLSSSTSTREIREEFKRFGDIIDLWMPRTQPT-----IAFVVYRYEEDAEKAI 1106

Query: 69   HNLDRKWICGRQIEIQFAQ 87
              +D + + GR++ +  A+
Sbjct: 1105 RRMDGESMHGRRVRVSLAR 1049
>31618
          Length = 716

 Score = 43.5 bits (101), Expect = 6e-05,   Method: Compositional matrix adjust.
 Identities = 23/71 (32%), Positives = 40/71 (56%)
 Frame = +1

Query: 12  LFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFEDVRDAEDALHNL 71
           LFV  ++ +T  ++LR  FG+YG I  + V  D  T R RGFA++ F +  +A D +   
Sbjct: 298 LFVGGLSWETTEKELRDHFGKYGEIESINVKTDPQTGRSRGFAFIVFTNT-EAIDQVSAA 474

Query: 72  DRKWICGRQIE 82
           +   I  ++++
Sbjct: 475 EEHIINSKKVD 507
>00029
          Length = 2204

 Score = 42.7 bits (99), Expect = 8e-05,   Method: Compositional matrix adjust.
 Identities = 23/80 (28%), Positives = 42/80 (52%)
 Frame = -3

Query: 12   LFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFEDVRDAEDALHNL 71
            +F+ N+ DDT  E+LR  F +YG + +  V         + F +V      +A+DA+ NL
Sbjct: 2130 IFIGNLGDDTDPEELRALFEKYGSVAECDV--------LKNFGFVHMVKKGEADDAISNL 1975

Query: 72   DRKWICGRQIEIQFAQGDRK 91
            +   I G+++ ++ + G  K
Sbjct: 1974 NGYNIGGQRMRVELSTGAGK 1915
>11019
          Length = 552

 Score = 42.0 bits (97), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 24/76 (31%), Positives = 37/76 (48%)
 Frame = -1

Query: 12  LFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFEDVRDAEDALHNL 71
           +FV  ++  T  ED++  F  YG I +  +  D  T R RGFA+V F D     D +  +
Sbjct: 228 IFVGGLSSSTTVEDIKNYFKAYGTIEEATLMFDKVTSRHRGFAFVTF-DNESTVDKVCEI 52

Query: 72  DRKWICGRQIEIQFAQ 87
               I  + +E + AQ
Sbjct: 51  HFHEINSKMVETKKAQ 4
>28652
          Length = 918

 Score = 41.6 bits (96), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 22/72 (30%), Positives = 39/72 (54%)
 Frame = -2

Query: 12  LFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFEDVRDAEDALHNL 71
           L+VRN+  D   +DL+ +FG YG +  V        ++ + + +V +ED  DA  AL +L
Sbjct: 194 LYVRNLTGDVTEDDLKEKFGAYGKVERV--------KKIKDYGFVHYEDREDALKALDDL 39

Query: 72  DRKWICGRQIEI 83
             + I   +I++
Sbjct: 38  HGEKIGNLEIDV 3

 Score = 33.1 bits (74), Expect = 0.068,   Method: Compositional matrix adjust.
 Identities = 22/75 (29%), Positives = 38/75 (50%), Gaps = 3/75 (4%)
 Frame = -2

Query: 8   PNTSLFVRNVADDTRSEDLRREFGRYGPI---VDVYVPLDFYTRRPRGFAYVQFEDVRDA 64
           PN  LFV N+      E++ +EF ++      V VY   D    + RGFA+++++  ++A
Sbjct: 494 PNLRLFVGNIPKSKTKEEILKEFEKHSEGLMDVIVYGSADNPKLKNRGFAFLEYDTHKNA 315

Query: 65  EDALHNLDRKWICGR 79
             A     R++  GR
Sbjct: 314 SAA----KRRFTTGR 282
>11126
          Length = 1061

 Score = 41.6 bits (96), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 24/73 (32%), Positives = 36/73 (49%)
 Frame = -3

Query: 11  SLFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFEDVRDAEDALHN 70
           S++V NV     +E+L + F   G +  V +  D Y+  P+GFAYV+F D      A   
Sbjct: 627 SVYVGNVDYGATAEELEQHFHGCGSVNRVTILCDKYSGHPKGFAYVEFADKDSVVTAKCT 448

Query: 71  LDRKWICGRQIEI 83
                  GRQI++
Sbjct: 447 GMDSLFRGRQIKV 409
>31310
          Length = 469

 Score = 40.8 bits (94), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 18/72 (25%), Positives = 42/72 (58%)
 Frame = -3

Query: 12  LFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFEDVRDAEDALHNL 71
           ++V ++  + R + +++ F  +GPI  V +  D  T + +GF++++++    A+ AL  +
Sbjct: 317 IYVGSINFEIREDTIKQAFLPFGPIKSVNLSWDPITNKHKGFSFIEYDVPEAAQLALEQM 138

Query: 72  DRKWICGRQIEI 83
           +   I GR I++
Sbjct: 137 NGVMIGGRNIKV 102
>11579
          Length = 1307

 Score = 40.8 bits (94), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 18/37 (48%), Positives = 27/37 (72%)
 Frame = +3

Query: 51 RGFAYVQFEDVRDAEDALHNLDRKWICGRQIEIQFAQ 87
          RGFA+V+F D RDAEDA+ ++D   + GR++  Q A+
Sbjct: 6  RGFAFVRFYDRRDAEDAMDSMDGALLDGREVRCQMAR 116
>30934
          Length = 809

 Score = 40.0 bits (92), Expect = 6e-04,   Method: Compositional matrix adjust.
 Identities = 19/50 (38%), Positives = 29/50 (58%)
 Frame = +1

Query: 34 GPIVDVYVPLDFYTRRPRGFAYVQFEDVRDAEDALHNLDRKWICGRQIEI 83
          GP+ D+ +P+D  T++ +GFA+V F     A  A   LDR+   GR + I
Sbjct: 28 GPVTDLDLPVDPITKKIKGFAHVTFMFPEHAVKARMELDRQGFRGRMLHI 177
>33516
          Length = 449

 Score = 38.9 bits (89), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 17/49 (34%), Positives = 29/49 (59%)
 Frame = +1

Query: 12  LFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFED 60
           +FV  ++ DT  + L+  F ++G I D  V ++  T + RGF +V F+D
Sbjct: 160 IFVGGLSWDTDQDSLQGYFSQFGEITDCIVMMNQQTGKSRGFGFVSFKD 306
>25950
          Length = 417

 Score = 38.1 bits (87), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 24/80 (30%), Positives = 39/80 (48%)
 Frame = -2

Query: 11  SLFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFEDVRDAEDALHN 70
           S++V NV     +E+L   F   G I  V +  +     P+GFAY++F      E AL  
Sbjct: 278 SVYVGNVDYGASAEELEAHFHGCGTINRVTILCNKADGHPKGFAYIEFGSKEYVETAL-A 102

Query: 71  LDRKWICGRQIEIQFAQGDR 90
           ++     GRQI++   + +R
Sbjct: 101 MNETLFRGRQIKVMTKRTNR 42
>03059
          Length = 1154

 Score = 37.4 bits (85), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 22/76 (28%), Positives = 39/76 (51%), Gaps = 1/76 (1%)
 Frame = -2

Query: 7   PPNTSLFVRNVADDTRSEDLRREFGRYGPIVDVYVPLD-FYTRRPRGFAYVQFEDVRDAE 65
           P  T + V  +  +   + ++  F  YG I  + +P D  +    +G AYV++E+  DAE
Sbjct: 679 PKPTKVHVGRLTRNVNKDHIQEIFSLYGTIKFIDLPNDRIHPNTSKGHAYVEYENPEDAE 500

Query: 66  DALHNLDRKWICGRQI 81
            A+  +D   I G++I
Sbjct: 499 KAVKYMDGGQIDGQEI 452
>28455
          Length = 573

 Score = 35.0 bits (79), Expect = 0.019,   Method: Compositional matrix adjust.
 Identities = 20/75 (26%), Positives = 35/75 (46%)
 Frame = -1

Query: 12  LFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFEDVRDAEDALHNL 71
           LFV+N+     +E L   F  +G + DV + + + +   +G AYV+FE    A  A+   
Sbjct: 534 LFVKNLPFTCSAEALETIFKEHGKVKDVRL-VTYRSGASKGLAYVEFETEEMATQAVMKT 358

Query: 72  DRKWICGRQIEIQFA 86
           D   +    I +  +
Sbjct: 357 DGLQVGDHMISVAIS 313
>14123
          Length = 448

 Score = 34.7 bits (78), Expect = 0.021,   Method: Compositional matrix adjust.
 Identities = 21/71 (29%), Positives = 33/71 (46%)
 Frame = -3

Query: 13  FVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFEDVRDAEDALHNLD 72
            V N+ D+    DL   F  Y P   + +    Y R  R  AY++   V D + A++NLD
Sbjct: 227 LVPNIKDEVIEADLVSLFAVYRP-KSIRIISTQYGRMHRKKAYIELGSVEDVKQAVNNLD 51

Query: 73  RKWICGRQIEI 83
           +    G  I++
Sbjct: 50  QSLYKGLHIKV 18
>22492
          Length = 785

 Score = 30.0 bits (66), Expect = 0.63,   Method: Compositional matrix adjust.
 Identities = 17/45 (37%), Positives = 27/45 (60%)
 Frame = +1

Query: 56  VQFEDVRDAEDALHNLDRKWICGRQIEIQFAQGDRKTPNQMKAKE 100
             F D RDAEDAL+ L+       +++I+FA+ +   P QM+ +E
Sbjct: 346 AMFVDPRDAEDALYYLNGTRFXRTELDIEFAR-ETGNPFQMRRRE 477
>03903
          Length = 983

 Score = 29.6 bits (65), Expect = 0.67,   Method: Compositional matrix adjust.
 Identities = 22/92 (23%), Positives = 40/92 (43%), Gaps = 8/92 (8%)
 Frame = -1

Query: 8   PNTSLFVRNVADDTRSEDLRREFGRY--------GPIVDVYVPLDFYTRRPRGFAYVQFE 59
           P+  L+++N++     EDL   FGRY          I D+ +       R +G A+V   
Sbjct: 464 PSRRLYIKNLSKQVTEEDLHWVFGRYVNWDKEEEKSIFDIRL---MKEGRMKGQAFVTLG 294

Query: 60  DVRDAEDALHNLDRKWICGRQIEIQFAQGDRK 91
               A  A+ + +     G+ I + FA+  ++
Sbjct: 293 TEEQARKAVKDTNAFVFKGKPIAVHFARSAKQ 198
>28605
          Length = 697

 Score = 28.1 bits (61), Expect = 2.0,   Method: Compositional matrix adjust.
 Identities = 19/79 (24%), Positives = 38/79 (48%), Gaps = 1/79 (1%)
 Frame = -3

Query: 9   NTSLFVRNVADDTRSE-DLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFEDVRDAEDA 67
           N+ +FV N++ D  SE +L+  F +YG ++D  V  + Y        +VQF    +   A
Sbjct: 572 NSRVFVANLSSDETSEAELQELFSKYGNVLDTLVHHNRY-------GFVQFSTEEEGRRA 414

Query: 68  LHNLDRKWICGRQIEIQFA 86
           +  ++      ++++   A
Sbjct: 413 VEAMNGYMFYRKKLKCNXA 357
>36728
          Length = 493

 Score = 27.3 bits (59), Expect = 3.7,   Method: Compositional matrix adjust.
 Identities = 11/25 (44%), Positives = 15/25 (60%)
 Frame = -2

Query: 50  PRGFAYVQFEDVRDAEDALHNLDRK 74
            +   +V+FEDV  A  ALH L+ K
Sbjct: 201 TKSILFVEFEDVEQARHALHKLNGK 127
>01513
          Length = 617

 Score = 26.2 bits (56), Expect = 8.8,   Method: Compositional matrix adjust.
 Identities = 15/40 (37%), Positives = 19/40 (47%)
 Frame = -3

Query: 2   SRYLRPPNTSLFVRNVADDTRSEDLRREFGRYGPIVDVYV 41
           SR L PPNT+L +      T+        G YGP V V +
Sbjct: 198 SRXLLPPNTALKLMXTIF*TKKGSSHGR*GCYGPYVCVLL 79
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|7305619|ref|NP_038728.1| ubiquitin specific protease
5 (isopeptidase T) [Mus musculus]
         (858 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

16704                                                                  65   8e-11
30550                                                                  51   2e-06
38889                                                                  45   9e-05
35122                                                                  37   0.049
11884                                                                  36   0.069
34364                                                                  32   1.2  
>16704
          Length = 387

 Score = 65.5 bits (158), Expect = 8e-11,   Method: Compositional matrix adjust.
 Identities = 31/61 (50%), Positives = 42/61 (68%), Gaps = 2/61 (3%)
 Frame = +3

Query: 725 EDCVTTIVSMGFSRDQALKALRATNNSLERAVDWIFSHIDDLDA--EAAMDISEGRSAAE 782
           E+ V  I +MGF+R QA+KAL+AT+N++ERA DWIFSH D+LD   E  M+       A+
Sbjct: 180 EEAVMMISAMGFTRPQAIKALKATDNNIERAADWIFSHADELDQPDEVPMETQASDQPAQ 359

Query: 783 S 783
           S
Sbjct: 360 S 362
>30550
          Length = 329

 Score = 51.2 bits (121), Expect = 2e-06,   Method: Composition-based stats.
 Identities = 22/43 (51%), Positives = 28/43 (65%)
 Frame = -2

Query: 663 LVEMGFPMDACRKAVYYTGNSGAEAAMNWVMSHMDDPDFANPL 705
           LVEMGFP     KA+  TG  G + AM+W+M+H DDPD   P+
Sbjct: 163 LVEMGFPKHRAEKALAKTGYKGVQIAMDWIMAHEDDPDIDVPM 35

 Score = 40.8 bits (94), Expect = 0.003,   Method: Composition-based stats.
 Identities = 21/46 (45%), Positives = 29/46 (63%), Gaps = 1/46 (2%)
 Frame = -2

Query: 730 TIVSMGFSRDQALKALRATN-NSLERAVDWIFSHIDDLDAEAAMDI 774
           T+V MGF + +A KAL  T    ++ A+DWI +H DD D +  MDI
Sbjct: 166 TLVEMGFPKHRAEKALAKTGYKGVQIAMDWIMAHEDDPDIDVPMDI 29
>38889
          Length = 426

 Score = 45.4 bits (106), Expect = 9e-05,   Method: Compositional matrix adjust.
 Identities = 20/43 (46%), Positives = 32/43 (74%)
 Frame = -2

Query: 725 EDCVTTIVSMGFSRDQALKALRATNNSLERAVDWIFSHIDDLD 767
           E+ VT I+ MGF RDQ ++ALRA+ N+ +RAV++  S I +++
Sbjct: 167 ENMVTEIMMMGFERDQVVRALRASFNNPDRAVEYCLSGIPEVN 39
>35122
          Length = 1031

 Score = 36.6 bits (83), Expect = 0.049,   Method: Compositional matrix adjust.
 Identities = 11/26 (42%), Positives = 20/26 (76%)
 Frame = -3

Query: 326 TGIRNLGNSCYLNSVVQVLFSIPDFQ 351
            G+ NLGN+CY+N+ +Q L ++P+ +
Sbjct: 768 AGLANLGNTCYMNATIQCLRAVPELR 691
>11884
          Length = 952

 Score = 35.8 bits (81), Expect = 0.069,   Method: Compositional matrix adjust.
 Identities = 20/67 (29%), Positives = 30/67 (44%), Gaps = 4/67 (5%)
 Frame = +3

Query: 795 RDG-PGKYQLFAFISHMGTSTMCGHYVCHIKKEGR-WVIYNDQKV--CASEKPPKDLGYI 850
           R G P  Y L+  + H G     GHY C+++     W I ND  V   ++ +      Y+
Sbjct: 366 RQGDPEYYHLYGVLIHSGHHCNMGHYYCYVRSPANSWYIMNDSSVHQVSASRVFGSQAYL 545

Query: 851 YFYQRVV 857
            FY + V
Sbjct: 546 LFYTKAV 566
>34364
          Length = 905

 Score = 32.0 bits (71), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 14/36 (38%), Positives = 21/36 (58%)
 Frame = -2

Query: 725 EDCVTTIVSMGFSRDQALKALRATNNSLERAVDWIF 760
           ED V  ++ MGFS D   +ALR T+N + +A   + 
Sbjct: 649 EDQVQRLIEMGFSDDSVRRALRMTDNDIAQATAILL 542
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|171906571|ref|NP_080479.2| Abelson helper integration
site 1 [Mus musculus]
         (1047 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

13664                                                                  65   1e-10
12574                                                                  54   3e-07
12806                                                                  54   5e-07
17602                                                                  52   1e-06
12324                                                                  50   4e-06
30256                                                                  50   5e-06
13335                                                                  49   8e-06
17598                                                                  49   8e-06
00561                                                                  49   9e-06
19498                                                                  49   1e-05
16716                                                                  47   3e-05
04088                                                                  45   1e-04
17807                                                                  45   1e-04
01598                                                                  45   2e-04
20131                                                                  45   2e-04
01494                                                                  45   2e-04
29687                                                                  44   3e-04
19949                                                                  44   3e-04
10264                                                                  43   6e-04
17286                                                                  42   0.001
15118                                                                  42   0.002
19469                                                                  41   0.002
28095                                                                  40   0.006
01805                                                                  39   0.010
20662                                                                  38   0.021
01327                                                                  37   0.037
01768                                                                  36   0.062
10162                                                                  36   0.083
30740                                                                  36   0.088
19863                                                                  35   0.13 
31384                                                                  35   0.13 
26939                                                                  35   0.15 
13278                                                                  35   0.17 
01462                                                                  35   0.21 
38177                                                                  34   0.31 
16105                                                                  34   0.32 
05642                                                                  34   0.35 
15115                                                                  34   0.35 
03156                                                                  34   0.39 
37180                                                                  33   0.45 
34005                                                                  33   0.49 
11915                                                                  33   0.54 
27465                                                                  33   0.81 
02090                                                                  33   0.82 
02147                                                                  33   0.88 
30482                                                                  32   0.92 
27681                                                                  32   1.1  
15972                                                                  32   1.1  
14500                                                                  32   1.5  
31054                                                                  32   1.5  
27525                                                                  32   1.7  
29912                                                                  32   1.8  
21105                                                                  32   1.9  
11228                                                                  31   2.0  
03395                                                                  31   2.1  
33180                                                                  31   2.6  
21921                                                                  31   2.6  
19140                                                                  30   4.3  
26032                                                                  30   4.9  
11322                                                                  30   5.9  
38362                                                                  30   6.8  
30297                                                                  29   8.6  
08480                                                                  29   8.9  
02960                                                                  29   9.2  
>13664
          Length = 507

 Score = 65.5 bits (158), Expect = 1e-10,   Method: Composition-based stats.
 Identities = 29/48 (60%), Positives = 34/48 (70%)
 Frame = +2

Query: 904 PPMVVALYDYTASRSDELTIHRGDIIRVYFKDNEDWWYGSVRKGQEGF 951
           P  VVALYDY A RSDELTI  GD+I +  KD+E WW G +  GQ+GF
Sbjct: 362 PKKVVALYDYKAQRSDELTILSGDVIMLLHKDSESWWMGELLDGQQGF 505
>12574
          Length = 521

 Score = 53.9 bits (128), Expect = 3e-07,   Method: Composition-based stats.
 Identities = 34/124 (27%), Positives = 66/124 (53%), Gaps = 1/124 (0%)
 Frame = +3

Query: 453 FSLNAGERGCFCLDFSHNGRILAAACASRDGYPIILYEIPSGRFMRELCGHLNIIYDLDW 512
           F+L    +    + FS NG  LA++ A +    I ++    G+F + + GH   + D+ W
Sbjct: 168 FTLAGHTKALSAVKFSPNGDWLASSSADK---LIKIWGAYDGKFEKTIAGHKLGLSDVAW 338

Query: 513 SKDDRYLVTSSSDGTARVWKNEINSTSTFRVLP-HPSFVYTAKFHPATRELVVTGCYDSM 571
           S D + L ++S D T ++W  E ++    + L  H ++V+   F+P +  L+V+G   S+
Sbjct: 339 SSDSKLLCSASDDKTLKIW--EFSTGKCMKTLKGHSNYVFCCNFNPQS-NLIVSG---SL 500

Query: 572 IRIW 575
           +R++
Sbjct: 501 MRVF 512
>12806
          Length = 961

 Score = 53.5 bits (127), Expect = 5e-07,   Method: Composition-based stats.
 Identities = 38/129 (29%), Positives = 60/129 (46%), Gaps = 2/129 (1%)
 Frame = +3

Query: 498 RELCGHLNIIYDLDWSKDDRYLVTSSSDGTARVWKNEINSTSTFRVLPHPSFVYTAKFHP 557
           + L GH + I DL  S D R+ ++SS D T R+W  +  ST++ R + H   V T  F P
Sbjct: 147 KTLTGHSHFISDLALSADSRFALSSSWDATLRLWDIKKGSTTS-RFINHTRDVLTVAFSP 323

Query: 558 ATRELVVTGCYDSMIRIWKIDAREDAAILVRQLDVHKSFVNSICF--DDEGHHMYSGDCI 615
             R+ + +G  D  ++IW I       +     + H  +V  + F  D +   + S    
Sbjct: 324 DNRQ-IASGGRDKNLKIWNIMGECKYTV---DANAHTDWVTCVRFHQDTKNPIVVSASND 491

Query: 616 GVIVVWDTY 624
             I VWD +
Sbjct: 492 KTIKVWDNH 518

 Score = 40.0 bits (92), Expect = 0.005,   Method: Composition-based stats.
 Identities = 28/137 (20%), Positives = 60/137 (43%), Gaps = 2/137 (1%)
 Frame = +3

Query: 488 LYEIPSGRFMRELCGHLNIIYDLDWSKDDRYLVTSSSDGTARVWKNEINSTSTFRVLPHP 547
           L++I  G        H   +  + +S D+R + +   D   ++W        T     H 
Sbjct: 243 LWDIKKGSTTSRFINHTRDVLTVAFSPDNRQIASGGRDKNLKIWNIMGECKYTVDANAHT 422

Query: 548 SFVYTAKFHPATRE-LVVTGCYDSMIRIWKIDAREDAAILVRQLDV-HKSFVNSICFDDE 605
            +V   +FH  T+  +VV+   D  I++W     ++  + ++   V HK+ + ++  D  
Sbjct: 423 DWVTCVRFHQDTKNPIVVSASNDKTIKVW-----DNHTMTLKNTFVGHKAQITAL--DMS 581

Query: 606 GHHMYSGDCIGVIVVWD 622
            +++ SG   G+ + W+
Sbjct: 582 TNYLVSGSKDGIAMTWN 632

 Score = 33.1 bits (74), Expect = 0.56,   Method: Compositional matrix adjust.
 Identities = 45/210 (21%), Positives = 79/210 (37%), Gaps = 38/210 (18%)
 Frame = +3

Query: 558 ATRELVVTGCYDSMIRIW----KIDAREDAAILV--RQLDVHKSFVNSICFDDEGHHMYS 611
           AT+  +++G  D+ I +W    K D  ED    V  + L  H  F++ +    +     S
Sbjct: 39  ATKPFLISGGRDNNIIVWDL*PKKDGDEDQTWGVPRKTLTGHSHFISDLALSADSRFALS 218

Query: 612 GDCIGVIVVWD------TYVKVNDVQ--------------------HSVRHWTINKEIKE 645
                 + +WD      T   +N  +                     +++ W I  E K 
Sbjct: 219 SSWDATLRLWDIKKGSTTSRFINHTRDVLTVAFSPDNRQIASGGRDKNLKIWNIMGECKY 398

Query: 646 TEFRGVPISYL---EVHPNGKRLLI--HTKDSTLRIMDLRILAARK-FVGAANYREKIHS 699
           T        ++     H + K  ++   + D T+++ D   +  +  FVG   ++ +I +
Sbjct: 399 TVDANAHTDWVTCVRFHQDTKNPIVVSASNDKTIKVWDNHTMTLKNTFVG---HKAQI-T 566

Query: 700 TLTPCGTLLFSGSEDGIVYVWNPETGEQVA 729
            L      L SGS+DGI   WN   G  V 
Sbjct: 567 ALDMSTNYLVSGSKDGIAMTWNVAEGSFVG 656
>17602
          Length = 481

 Score = 52.4 bits (124), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 40/151 (26%), Positives = 70/151 (46%), Gaps = 2/151 (1%)
 Frame = +3

Query: 573 RIWKIDAREDAAILVRQLDVHKSFVNSICFDDEGHHMYSGDCIGVIVVWDTYVKVNDVQH 632
           RIW +   +     ++ L  H   V ++ F+ +G  + S    G+  +WDT         
Sbjct: 3   RIWDVKTGK----CLKTLPAHSDPVTAVHFNRDGSLIVSSSYDGLCRIWDT--------- 143

Query: 633 SVRHWTINKEIKETEFRGVPISYLEVHPNGKRLLIHTKDSTLRIMDL-RILAARKFVGAA 691
                 +   I +      P+S+++  PNGK +L  T D+TL++ D  +    + +VG  
Sbjct: 144 -ASGQCLXTLIDDDN---PPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYVGHR 311

Query: 692 NYREKIHSTLT-PCGTLLFSGSEDGIVYVWN 721
           N +  I +  +   G  + SGSED +VY+WN
Sbjct: 312 NEKYCIFANFSVTGGKWIVSGSEDNMVYIWN 404

 Score = 30.8 bits (68), Expect = 2.9,   Method: Compositional matrix adjust.
 Identities = 26/108 (24%), Positives = 45/108 (41%)
 Frame = +3

Query: 529 RVWKNEINSTSTFRVLPHPSFVYTAKFHPATRELVVTGCYDSMIRIWKIDAREDAAILVR 588
           R+W  ++ +    + LP  S   TA        L+V+  YD + RIW   + +    L+ 
Sbjct: 3   RIW--DVKTGKCLKTLPAHSDPVTAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLXTLID 176

Query: 589 QLDVHKSFVNSICFDDEGHHMYSGDCIGVIVVWDTYVKVNDVQHSVRH 636
             +   SFV    F   G ++ +      + +WD Y K   ++  V H
Sbjct: 177 DDNPPVSFVK---FSPNGKYILAATLDNTLKLWD-YSKGKCLKTYVGH 308
>12324
          Length = 946

 Score = 50.1 bits (118), Expect = 4e-06,   Method: Composition-based stats.
 Identities = 24/51 (47%), Positives = 32/51 (62%)
 Frame = +3

Query: 907 VVALYDYTASRSDELTIHRGDIIRVYFKDNEDWWYGSVRKGQEGFFPANHV 957
           VVA+YDY A + DELT     +I V  K+++ WW G V  G  G FP+N+V
Sbjct: 696 VVAIYDYEAEKDDELTFSENSVIYVIRKNDDGWWEG-VMDGVTGLFPSNYV 845
>30256
          Length = 961

 Score = 50.1 bits (118), Expect = 5e-06,   Method: Composition-based stats.
 Identities = 71/283 (25%), Positives = 116/283 (40%), Gaps = 5/283 (1%)
 Frame = +3

Query: 493 SGRFMRELCGHLNIIYDLDWSKDDRYLVTSSSDGTARVWKNEINSTSTFRVL-PHPSFVY 551
           +G     L GH + +  L  S   + +V+ S D T RVW  +I S     VL  H + V 
Sbjct: 129 TGVCTHTLYGHSSTVRCLSLS--GKKVVSGSRDATLRVW--DIESGHCLNVLLGHMAAVR 296

Query: 552 TAKFHPATRELVVTGCYDSMIRIWKIDAREDAAILVRQLDVHKSFVNSICFDDEGHHMYS 611
             ++     + VV+G  D  +R+W      D A  +  L  H + V S+ FD  G ++ S
Sbjct: 297 CVQYDG---KRVVSGAXDYTVRVWD----PDTASCLHTLQGHTNRVYSLQFD--GVYVVS 449

Query: 612 GDCIGVIVVWDTYVKVNDVQHSVR-HWTINKEIKETEFRGVPISYLEVHPNGKRLLIHTK 670
           G     I VWD  V+   + H++  H ++              S LE+  N   L+    
Sbjct: 450 GSLDTSIRVWD--VRCGKLVHTLMGHQSLT-------------SGLELKDN--LLVSGNA 578

Query: 671 DSTLRIMDLRILAARKFVGAANYREKIHSTLTPCGTLLFSGSEDGIVYVWNPETGEQVAM 730
           DST+++ D+      + +   N      + L      + + S+DG V +W+  TG+ +  
Sbjct: 579 DSTVKVWDVHTGKCLQTLLGPNKHRSAVTCLQFNKKFVVTCSDDGTVKLWDLNTGDFIRN 758

Query: 731 YSDLPFKSTIRDISYHPLENMVAFCAFGQ---SEPILLYIYDF 770
              LP   +   +      N    CA G    +E   L + DF
Sbjct: 759 LITLPSGGSGGVVWRLRCNNTKMVCAVGSRNGTEETKLLVLDF 887
>13335
          Length = 863

 Score = 49.3 bits (116), Expect = 8e-06,   Method: Composition-based stats.
 Identities = 40/162 (24%), Positives = 67/162 (41%), Gaps = 17/162 (10%)
 Frame = +1

Query: 479 ASRDGYPIILYEIPSGRFMRELCGHLNIIYDLDWSKDDRYLVTSSSDGTARVWKNEINST 538
           +  D   I ++E+ + + +R   GH + +  L +S +  YLV+ S +G   VW       
Sbjct: 112 SGSDDDTICMWEVATQKLVRSYVGHEDSVMALAYSPNGHYLVSGSPNGDLYVWDASFGHC 291

Query: 539 S--TFRVLPHPSFVYTAKFHP----ATRE-------LVVTGCYDSMIRIWKIDAREDAAI 585
              T RV  H   V   +F P    A  E       L+ TG  D++I++W   A+  +  
Sbjct: 292 RHLTLRVDAHDLGVTCCEFSPTFGTACAENSSTCNLLLATGGKDNLIKLWTFSAQVGSPE 471

Query: 586 LVRQ----LDVHKSFVNSICFDDEGHHMYSGDCIGVIVVWDT 623
           +  Q    L  H   V +  F      + SG     + +WD+
Sbjct: 472 VTLQCRDILSGHSDLVMACAFSPSSALLASGSFDKSVRLWDS 597

 Score = 29.6 bits (65), Expect = 5.8,   Method: Composition-based stats.
 Identities = 26/109 (23%), Positives = 48/109 (44%), Gaps = 1/109 (0%)
 Frame = +1

Query: 618 IVVWDTYVKVNDVQHSVRHWTINKEIKETEFRGVPISYLEVHPNGKRLLIHTKDSTLRIM 677
           ++VWD  VK   ++   +H +    I+  +F           P+   L+  + D T+ + 
Sbjct: 4   VIVWD--VKTGSIKGEYQHAS-KSSIRVCKFS----------PSSSHLVSGSDDDTICMW 144

Query: 678 DLRILA-ARKFVGAANYREKIHSTLTPCGTLLFSGSEDGIVYVWNPETG 725
           ++      R +VG  +    +    +P G  L SGS +G +YVW+   G
Sbjct: 145 EVATQKLVRSYVGHED--SVMALAYSPNGHYLVSGSPNGDLYVWDASFG 285
>17598
          Length = 875

 Score = 49.3 bits (116), Expect = 8e-06,   Method: Compositional matrix adjust.
 Identities = 58/256 (22%), Positives = 108/256 (42%), Gaps = 4/256 (1%)
 Frame = +1

Query: 498 RELCGHLNIIYDLDWSKDDRYLVTSSSDGTARVWKNEINSTSTFRVLPHPSFVYTAKFHP 557
           R L GH + + D+  S D RY+++SS D T R+W  +  +T T R + H        F P
Sbjct: 103 RTLQGHSHFVSDVSLSADSRYVLSSSWDATLRLWDIKKGNT-TRRFISHTRDALAVAFSP 279

Query: 558 ATRELVVTGCYDSMIRIWKIDAREDAAILVRQLDVHKSFVNSICF--DDEGHHMYSGDCI 615
             R+ + +G  D  ++IW         +     + H+ +V  + F  D +   + S    
Sbjct: 280 DNRQ-IASGGRDKALKIWNTVGECKFTV---DANSHQDWVTCVKFHQDAKSPLVVSASMD 447

Query: 616 GVIVVWDTYVKVNDVQHS-VRHWTINKEIKETEFRGVPISYLEVHPNGKRLLIHTKDSTL 674
             I VWD       ++H+ V H        +T+   + ++    +     L   +KD  +
Sbjct: 448 KTIKVWDNQTMT--LKHTFVGH--------KTQINAIDLALKTYY-----LASGSKDGIV 582

Query: 675 RIMDLRILAARKFVGAANYREKIHST-LTPCGTLLFSGSEDGIVYVWNPETGEQVAMYSD 733
              +++      F+G  +   ++++   +P    LF G+ +GI  +W            D
Sbjct: 583 MTWNIQ---NGTFLGKIDCDCEVNAVKFSPNKYWLFVGTSEGI-QIW------------D 714

Query: 734 LPFKSTIRDISYHPLE 749
           LP +  I+DI   P++
Sbjct: 715 LPNQKKIKDIRASPID 762

 Score = 48.9 bits (115), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 32/137 (23%), Positives = 61/137 (44%), Gaps = 2/137 (1%)
 Frame = +1

Query: 488 LYEIPSGRFMRELCGHLNIIYDLDWSKDDRYLVTSSSDGTARVWKNEINSTSTFRVLPHP 547
           L++I  G   R    H      + +S D+R + +   D   ++W        T     H 
Sbjct: 199 LWDIKKGNTTRRFISHTRDALAVAFSPDNRQIASGGRDKALKIWNTVGECKFTVDANSHQ 378

Query: 548 SFVYTAKFHP-ATRELVVTGCYDSMIRIWKIDAREDAAILVRQLDV-HKSFVNSICFDDE 605
            +V   KFH  A   LVV+   D  I++W     ++  + ++   V HK+ +N+I    +
Sbjct: 379 DWVTCVKFHQDAKSPLVVSASMDKTIKVW-----DNQTMTLKHTFVGHKTQINAIDLALK 543

Query: 606 GHHMYSGDCIGVIVVWD 622
            +++ SG   G+++ W+
Sbjct: 544 TYYLASGSKDGIVMTWN 594
>00561
          Length = 1003

 Score = 49.3 bits (116), Expect = 9e-06,   Method: Composition-based stats.
 Identities = 29/136 (21%), Positives = 60/136 (44%), Gaps = 1/136 (0%)
 Frame = -3

Query: 488 LYEIPSGRFMRELCGHLNIIYDLDWSKDDRYLVTSSSDGTARVWKNEINSTSTFRVLPHP 547
           L+++ +G+  R   GH   +  + +S D+R +V+ S D T ++W        T +   H 
Sbjct: 788 LWDLAAGKTTRRFEGHTKDVLSVAFSADNRQIVSGSRDKTIKLWNTLAECKFTIQEDGHT 609

Query: 548 SFVYTAKFHPATRELVVTGC-YDSMIRIWKIDAREDAAILVRQLDVHKSFVNSICFDDEG 606
            +V   +F P     ++  C +D  +++W +   +    L      H  ++N++    +G
Sbjct: 608 DWVSCVRFSPNHSNPIIVSCGWDRTVKVWNLANCK----LKNNHHGHNGYLNTVTVSPDG 441

Query: 607 HHMYSGDCIGVIVVWD 622
               SG      ++WD
Sbjct: 440 SLCTSGGKDSKALLWD 393
>19498
          Length = 903

 Score = 48.5 bits (114), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 45/176 (25%), Positives = 72/176 (40%), Gaps = 18/176 (10%)
 Frame = -1

Query: 428 LEDSKEEVKWKRLPGQACRIPNKHLFSLNAGERGCFCLDFSHNGRILAAACASRDGYPII 487
           + D KEE     +P   C++ + HL  +N       C+ +S NG+ LA+     D   I+
Sbjct: 852 IRDEKEEAD-DDVPRVLCQM-DSHLGCVN-------CVRWSENGKFLASG---GDDKLIM 709

Query: 488 LYEIPSG-----------------RFMRELCGHLNIIYDLDWSKDDRYLVTSSSDGTARV 530
           +++I  G                 R +  L GH   + DL WS  D +L + S D T  V
Sbjct: 708 IWQISRGFGSGKSFGSNVTILEHWRSVATLRGHAGDVLDLAWSPQDLWLASCSVDNTIVV 529

Query: 531 WKNEINSTSTFRVLPHPSFVYTAKFHPATRELVVTGCYDSMIRIWKI-DAREDAAI 585
           W     S     +  H   V    + P  R L  +   D  +R+W+  D +E+  +
Sbjct: 528 WNALKFSEQVAVIRGHAGMVKGVTWDPVGRYL-ASQSDDKTLRVWRTSDWKEETCV 364
>16716
          Length = 934

 Score = 47.4 bits (111), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 23/51 (45%), Positives = 30/51 (58%)
 Frame = -1

Query: 907 VVALYDYTASRSDELTIHRGDIIRVYFKDNEDWWYGSVRKGQEGFFPANHV 957
            +ALYDY A+  DELT    D+I      ++ WW GS   G+ G FPAN+V
Sbjct: 463 AIALYDYQAADDDELTFDPDDVITDIEMIDDGWWRGSCH-GKNGLFPANYV 314
>04088
          Length = 511

 Score = 45.4 bits (106), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 33/111 (29%), Positives = 57/111 (51%), Gaps = 4/111 (3%)
 Frame = +3

Query: 650 GVPISYLEVHPNGKRLLIHTKDSTLRIMDLRI-LAARKFVGAANYREKIHSTLTPCGTLL 708
           G  ++ +    +G+  L+ ++D+T+R+MD        +F G  + + KI S L    TL+
Sbjct: 30  GKAVTSVTFTRDGQCSLVSSQDNTVRLMDKDTGEMLNEFTGHKHSQYKIDSCLNNEDTLV 209

Query: 709 FSGSEDGIVYVWNPETGEQVAMYSDLPFKST--IRDISYHPLE-NMVAFCA 756
            SGSEDG VY W+     +  +   L  K+T  +  +S+H  E  ++  CA
Sbjct: 210 VSGSEDGKVYFWDL---VEAKLVDTLDHKTTRPVHSLSFHHAELCLMTACA 353
>17807
          Length = 484

 Score = 45.1 bits (105), Expect = 1e-04,   Method: Composition-based stats.
 Identities = 34/165 (20%), Positives = 70/165 (42%), Gaps = 3/165 (1%)
 Frame = -2

Query: 544 LPHPSFVYTAKFHPATRELVVTGCYDSMIRIWKIDAREDAAILVRQLDVHKSFVNSICFD 603
           LP     +  + HP      ++G  D  IR+W I  ++    +  +L    + + +  F 
Sbjct: 471 LPTHRLCHRHRLHPKDDRYFLSGSLDGKIRLWNIPDKK--VTMWNELSGSSNLITTASFC 298

Query: 604 DEGHHMYSGDCIGVIVVWDTYVKVNDVQHSVRHWTI--NKEIKETEFRGVPISYLEVHPN 661
             G     G   G  + + T          ++++T+   +  +    RG  I+ +E  P 
Sbjct: 297 HNGRLAVVGTYDGRCIFYTT--------DQLKYYTMLNVRSTRGRNARGRKITGIEAMPG 142

Query: 662 GKRLLIHTKDSTLRIMDLRILAAR-KFVGAANYREKIHSTLTPCG 705
            +++L+ + DS +R+  L+ L    K+ G  N   +I ++ +P G
Sbjct: 141 EEKILVTSNDSRVRLYSLKDLTLTCKYKGCTNNSSQIKASFSPTG 7

 Score = 33.1 bits (74), Expect = 0.65,   Method: Composition-based stats.
 Identities = 22/66 (33%), Positives = 29/66 (43%), Gaps = 1/66 (1%)
 Frame = -2

Query: 514 KDDRYLVTSSSDGTARVWKNEINSTSTFRVLPHPS-FVYTAKFHPATRELVVTGCYDSMI 572
           KDDRY ++ S DG  R+W       + +  L   S  + TA F    R L V G YD   
Sbjct: 429 KDDRYFLSGSLDGKIRLWNIPDKKVTMWNELSGSSNLITTASFCHNGR-LAVVGTYDGRC 253

Query: 573 RIWKID 578
             +  D
Sbjct: 252 IFYTTD 235
>01598
          Length = 1545

 Score = 45.1 bits (105), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 37/130 (28%), Positives = 59/130 (45%), Gaps = 9/130 (6%)
 Frame = +1

Query: 457  AGERGCFCLDFSHNGRI-----LAAACASRDG---YPIILYEIPSGRFMRELCGHLNIIY 508
            AG   C  L  + N ++     LA+  A R+G     +IL        +REL GH   + 
Sbjct: 1153 AGSPCCHWLAAAGNDQVIHVVDLASVFAEREGDKETSLILTS------LRELSGHSQRVT 1314

Query: 509  DLDWS-KDDRYLVTSSSDGTARVWKNEINSTSTFRVLPHPSFVYTAKFHPATRELVVTGC 567
            D+ WS   D  LV+   D  A VW  +   T+  +   H   + T +F     +LV+TG 
Sbjct: 1315 DMSWSPHHDARLVSVGYDAEAFVWDVQ-KGTALAQFKGHMGRLLTCQFSGLDPDLVMTGG 1491

Query: 568  YDSMIRIWKI 577
             D+ + +W++
Sbjct: 1492 SDASVHVWRV 1521
>20131
          Length = 574

 Score = 45.1 bits (105), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 21/50 (42%), Positives = 33/50 (66%)
 Frame = -2

Query: 908 VALYDYTASRSDELTIHRGDIIRVYFKDNEDWWYGSVRKGQEGFFPANHV 957
           VA+Y Y +  + +LT + GD+I V  KD EDWW G++ + + G FP+ +V
Sbjct: 471 VAMYSYVSGETADLTFNEGDMILVTKKD-EDWWTGTLGE-KTGMFPSTYV 328

 Score = 43.9 bits (102), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 28/94 (29%), Positives = 48/94 (51%), Gaps = 7/94 (7%)
 Frame = -2

Query: 884 LPQTAFISIERGPFVRHVDPPPMVVALYDYTASRSDELTIHRGDIIRVYFKDNEDWWYGS 943
            P T    +E  P  +    P + + +  YTA+ + +L++  G++I V  K    WW G 
Sbjct: 345 FPSTYVKKVEIQPGQKSAKKPEIAMVIAPYTATGNGQLSLEPGNLIHVRQKSPRGWWEGE 166

Query: 944 VR-KGQE---GFFPANHVA--SETLYRDSP-PKV 970
           ++ +GQ    G+FPA++V     +  R +P PKV
Sbjct: 165 LQARGQRKKIGWFPADYVKPLGSSSARSTPDPKV 64
>01494
          Length = 2122

 Score = 45.1 bits (105), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 20/51 (39%), Positives = 30/51 (58%)
 Frame = +3

Query: 907 VVALYDYTASRSDELTIHRGDIIRVYFKDNEDWWYGSVRKGQEGFFPANHV 957
           V AL+DY A+R DEL+  +G II    + +  WW G     ++ +FP+N V
Sbjct: 312 VKALHDYNANRDDELSFCKGAIITNVSRQDGGWWRGDYGAKKQHWFPSNFV 464
>29687
          Length = 434

 Score = 44.3 bits (103), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 20/51 (39%), Positives = 30/51 (58%)
 Frame = -2

Query: 907 VVALYDYTASRSDELTIHRGDIIRVYFKDNEDWWYGSVRKGQEGFFPANHV 957
           V AL+DY A R DEL+  +G II    + +  WW G     ++ +FP+N+V
Sbjct: 292 VKALHDYNAKREDELSFCKGAIITNVSRQDGGWWRGDYGTKKQHWFPSNYV 140
>19949
          Length = 903

 Score = 43.9 bits (102), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 37/148 (25%), Positives = 65/148 (43%)
 Frame = +2

Query: 465 LDFSHNGRILAAACASRDGYPIILYEIPSGRFMRELCGHLNIIYDLDWSKDDRYLVTSSS 524
           LDF   G   A+     +   + L++I     +    GH   +  L +S D R++ ++S 
Sbjct: 11  LDFHPYGAYTASGSMDCN---VKLWDIRRKGCIYTYKGHTGCVCCLRFSPDGRWIASASE 181

Query: 525 DGTARVWKNEINSTSTFRVLPHPSFVYTAKFHPATRELVVTGCYDSMIRIWKIDAREDAA 584
           DG  ++W        T   L H   V T +FHP    L+ +G  D  ++ W ++  +   
Sbjct: 182 DGLVKLWDLTAGKLLTDLKL-HRDAVNTIEFHPH-EFLLASGSADRTVKFWDLETFQ--- 346

Query: 585 ILVRQLDVHKSFVNSICFDDEGHHMYSG 612
            L+   +   + + SI F  +G  +YSG
Sbjct: 347 -LISTTEPEANSIRSILFHPDGVCLYSG 427

 Score = 38.1 bits (87), Expect = 0.020,   Method: Compositional matrix adjust.
 Identities = 29/108 (26%), Positives = 49/108 (45%), Gaps = 7/108 (6%)
 Frame = +2

Query: 653 ISYLEVHPNGKRLLIHTKDSTLRIMDLRILAARKFVGAANYREKIHSTLTPC------GT 706
           +  L+ HP G      + D  +++ D+R    RK      Y  K H+    C      G 
Sbjct: 2   VKSLDFHPYGAYTASGSMDCNVKLWDIR----RK---GCIYTYKGHTGCVCCLRFSPDGR 160

Query: 707 LLFSGSEDGIVYVWNPETGEQVAMYSDLPF-KSTIRDISYHPLENMVA 753
            + S SEDG+V +W+   G+   + +DL   +  +  I +HP E ++A
Sbjct: 161 WIASASEDGLVKLWDLTAGK---LLTDLKLHRDAVNTIEFHPHEFLLA 295
>10264
          Length = 416

 Score = 43.1 bits (100), Expect = 6e-04,   Method: Composition-based stats.
 Identities = 25/82 (30%), Positives = 41/82 (50%), Gaps = 1/82 (1%)
 Frame = -1

Query: 497 MRELCGHLNIIYDLDWS-KDDRYLVTSSSDGTARVWKNEINSTSTFRVLPHPSFVYTAKF 555
           +REL GH   + D+ WS   D  LV+   D  A VW  +   T+  +   H   + T +F
Sbjct: 266 LRELSGHSQRVTDMSWSPHHDARLVSVGYDAEAFVWDVQ-KGTALAQFKGHMGRLLTCQF 90

Query: 556 HPATRELVVTGCYDSMIRIWKI 577
                +LV+TG  D+ + +W++
Sbjct: 89  SGLDPDLVMTGGSDASVHVWRV 24
>17286
          Length = 489

 Score = 42.0 bits (97), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 20/53 (37%), Positives = 31/53 (58%)
 Frame = +3

Query: 905 PMVVALYDYTASRSDELTIHRGDIIRVYFKDNEDWWYGSVRKGQEGFFPANHV 957
           P   A+YD+      EL    GD+I +  + +E+W+ GSV  G+ G+FP N+V
Sbjct: 24  PCARAIYDFLPESDGELGFQEGDMITLISQVDENWFEGSVH-GKVGYFPINYV 179
>15118
          Length = 1074

 Score = 41.6 bits (96), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 18/49 (36%), Positives = 29/49 (59%)
 Frame = +3

Query: 484 YPIILYEIPSGRFMRELCGHLNIIYDLDWSKDDRYLVTSSSDGTARVWK 532
           + + + ++ + R +R   GH N I DL +S D R+L+T+S D T R W 
Sbjct: 393 FTVSVIDVDTLRVVRVFSGHSNSITDLSFSGDGRWLITASMDCTVRTWS 539
>19469
          Length = 428

 Score = 41.2 bits (95), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 21/52 (40%), Positives = 29/52 (55%), Gaps = 3/52 (5%)
 Frame = -1

Query: 909 ALYDYTASRSDELTIHRGDIIRVYFKDN---EDWWYGSVRKGQEGFFPANHV 957
           ALYD  A   DEL   RGD+I +  +D    + WW  S+R G++G  P N +
Sbjct: 353 ALYDNIAETPDELAFRRGDVITILEQDTAGLDGWWLCSLR-GRQGIAPGNRL 201
>28095
          Length = 597

 Score = 39.7 bits (91), Expect = 0.006,   Method: Composition-based stats.
 Identities = 21/50 (42%), Positives = 29/50 (58%), Gaps = 1/50 (2%)
 Frame = +3

Query: 909 ALYDYTASRSDELTIHRGDIIRVYFKDNEDWWYGSV-RKGQEGFFPANHV 957
           A+YDY A+ SDE++ + GD I      +  W  G V R GQ G  P+N+V
Sbjct: 270 AMYDYQAADSDEVSFNDGDTIIECQPVDAGWMTGRVERTGQYGMLPSNYV 419
>01805
          Length = 2124

 Score = 38.9 bits (89), Expect = 0.010,   Method: Compositional matrix adjust.
 Identities = 23/85 (27%), Positives = 43/85 (50%), Gaps = 6/85 (7%)
 Frame = -1

Query: 502 GHLNIIYDLDWSKDDRY-LVTSSSDGTARVW-----KNEINSTSTFRVLPHPSFVYTAKF 555
           GH   + DL W+++ R+ L ++S+D T  +W     K  +N T       H   V    +
Sbjct: 582 GHTQAVLDLSWNRNARHVLASASADTTVALWDLSEGKMAMNFTQ------HSREVQCCNW 421

Query: 556 HPATRELVVTGCYDSMIRIWKIDAR 580
           HP   + ++TG +D+ +++  +D R
Sbjct: 420 HPQEEQTLLTGSFDNTVKV--VDCR 352
>20662
          Length = 1220

 Score = 38.1 bits (87), Expect = 0.021,   Method: Compositional matrix adjust.
 Identities = 20/91 (21%), Positives = 40/91 (43%)
 Frame = +2

Query: 496 FMRELCGHLNIIYDLDWSKDDRYLVTSSSDGTARVWKNEINSTSTFRVLPHPSFVYTAKF 555
            +   C H ++   +  + D  + +++S D   +VW  ++ S  T+R   H   V+  + 
Sbjct: 362 MLSSACEHDDMTASVSINSDXSHYLSASYDHGIKVWNTDLTSLYTYRA--HSDIVWDVQC 535

Query: 556 HPATRELVVTGCYDSMIRIWKIDAREDAAIL 586
           HP    L ++   D  I +W +   + A  L
Sbjct: 536 HPTEPALFLSCSQDGKIVLWDVRESKPATCL 628
>01327
          Length = 2215

 Score = 37.0 bits (84), Expect = 0.037,   Method: Compositional matrix adjust.
 Identities = 30/116 (25%), Positives = 53/116 (45%)
 Frame = +3

Query: 485 PIILYEIPSGRFMRELCGHLNIIYDLDWSKDDRYLVTSSSDGTARVWKNEINSTSTFRVL 544
            ++LY+  +GR      GH   I  + +      + ++S D T ++W+   NS S    +
Sbjct: 108 SVVLYDYQNGRLEDRWTGHDREITKVCYGASCNGMFSASRDKTIKMWQRG-NSHSIRDFI 284

Query: 545 PHPSFVYTAKFHPATRELVVTGCYDSMIRIWKIDAREDAAILVRQLDVHKSFVNSI 600
            H   V TA        L+ +G  D+ +RIW +   E  A L RQ ++ ++ V  +
Sbjct: 285 GHD-MVVTAIHLNTDNTLLCSGSRDNTVRIWDV---ETGACL-RQNNIPQNLVTDV 437

 Score = 33.9 bits (76), Expect = 0.32,   Method: Compositional matrix adjust.
 Identities = 24/97 (24%), Positives = 46/97 (47%)
 Frame = +3

Query: 479 ASRDGYPIILYEIPSGRFMRELCGHLNIIYDLDWSKDDRYLVTSSSDGTARVWKNEINST 538
           ASRD   I +++  +   +R+  GH  ++  +  + D+  L + S D T R+W  E  + 
Sbjct: 219 ASRD-KTIKMWQRGNSHSIRDFIGHDMVVTAIHLNTDNTLLCSGSRDNTVRIWDVETGAC 395

Query: 539 STFRVLPHPSFVYTAKFHPATRELVVTGCYDSMIRIW 575
                +P  + V   K+ P +  L++    D  +RI+
Sbjct: 396 LRQNNIPQ-NLVTDVKWLPGS-HLIIQAGEDKEVRIY 500

 Score = 32.3 bits (72), Expect = 0.91,   Method: Compositional matrix adjust.
 Identities = 21/68 (30%), Positives = 36/68 (52%)
 Frame = +3

Query: 685 RKFVGAANYREKIHSTLTPCGTLLFSGSEDGIVYVWNPETGEQVAMYSDLPFKSTIRDIS 744
           R F+G       IH  L    TLL SGS D  V +W+ ETG  +   +++P ++ + D+ 
Sbjct: 273 RDFIGHDMVVTAIH--LNTDNTLLCSGSRDNTVRIWDVETGACLRQ-NNIP-QNLVTDVK 440

Query: 745 YHPLENMV 752
           + P  +++
Sbjct: 441 WLPGSHLI 464
>01768
          Length = 1424

 Score = 36.2 bits (82), Expect = 0.062,   Method: Compositional matrix adjust.
 Identities = 40/203 (19%), Positives = 79/203 (38%), Gaps = 10/203 (4%)
 Frame = +3

Query: 489 YEIPSGRFMRELCGHLNIIYDLDWSKDDR-YLVTSSSDGTARV-------WKNEINSTST 540
           Y+      +  +  H    + +DWS   + +LVT    G   +       W  E +S + 
Sbjct: 654 YDSTQKSIVHTVTHHTTEGFAIDWSPAAKGWLVTGDCTGAIYISQPSSSGWTTEKSSYAA 833

Query: 541 FRVLPHPSFVYTAKFHPATRELVVTGCYDSMIRIWKIDAREDAAILVRQLDVHKSFVNSI 600
                H   V   ++ P    +  +   D  +RIW    +   A ++   + H   +N I
Sbjct: 834 -----HTDSVEDVQWSPNEGNVFASCSVDRTLRIWNTQQKPSKANVLTVPEAHSRDINVI 998

Query: 601 CFDD-EGHHMYSGDCIGVIVVWDTYVKVNDVQHSVRHWTINKEIKETEFRGVPISYLEVH 659
            ++  E H + SG   G+I +WD  +  N    +   + ++ +         P++ LE +
Sbjct: 999 NWNPIEKHLLASGGDDGIIKIWDLRMFRNKPVSAQASFKLHSQ---------PVTSLEWN 1151

Query: 660 PNGKRLLIHT-KDSTLRIMDLRI 681
           P    +L  + +D  + I D  +
Sbjct: 1152PQDSSVLAASGEDDQITIWDFSV 1220

 Score = 32.0 bits (71), Expect = 1.4,   Method: Compositional matrix adjust.
 Identities = 47/203 (23%), Positives = 81/203 (39%), Gaps = 18/203 (8%)
 Frame = +3

Query: 609 MYSGDCIGVIVVWDTYVKVNDVQHSVRHWTINKEIKETEFRGVPISYLEVHPN-GKRLLI 667
           + +GDC G I +          Q S   WT  K         V    ++  PN G     
Sbjct: 747 LVTGDCTGAIYI---------SQPSSSGWTTEKSSYAAHTDSV--EDVQWSPNEGNVFAS 893

Query: 668 HTKDSTLRIMDLRILAARK---FVGAANYREKIHSTLTPCGT-LLFSGSEDGIVYVWNPE 723
            + D TLRI + +   ++     V  A+ R+       P    LL SG +DGI+ +W+  
Sbjct: 894 CSVDRTLRIWNTQQKPSKANVLTVPEAHSRDINVINWNPIEKHLLASGGDDGIIKIWDLR 1073

Query: 724 TGEQVAMYSDLPFK---STIRDISYHPLENMVAFCAFGQSEPILLYIYDFQVAQQE---- 776
                 + +   FK     +  + ++P ++ V   A G+ + I   I+DF V + E    
Sbjct: 1074MFRNKPVSAQASFKLHSQPVTSLEWNPQDSSV-LAASGEDDQIT--IWDFSVERDEGEGE 1244

Query: 777 ------AEMLKRYSGTLPLPGIH 793
                 A++L ++ G   +  +H
Sbjct: 1245EELDVPAQLLFQHCGQTDIKEVH 1313

 Score = 31.6 bits (70), Expect = 1.8,   Method: Compositional matrix adjust.
 Identities = 22/107 (20%), Positives = 48/107 (44%), Gaps = 7/107 (6%)
 Frame = +3

Query: 502  GHLNIIYDLDWSKDDRYLVTSSSD-GTARVW-----KNE-INSTSTFRVLPHPSFVYTAK 554
             H   I  ++W+  +++L+ S  D G  ++W     +N+ +++ ++F++   P  V + +
Sbjct: 972  AHSRDINVINWNPIEKHLLASGGDDGIIKIWDLRMFRNKPVSAQASFKLHSQP--VTSLE 1145

Query: 555  FHPATRELVVTGCYDSMIRIWKIDAREDAAILVRQLDVHKSFVNSIC 601
            ++P    ++     D  I IW      D      +LDV    +   C
Sbjct: 1146 WNPQDSSVLAASGEDDQITIWDFSVERDEGEGEEELDVPAQLLFQHC 1286
>10162
          Length = 1629

 Score = 35.8 bits (81), Expect = 0.083,   Method: Compositional matrix adjust.
 Identities = 31/133 (23%), Positives = 58/133 (43%), Gaps = 8/133 (6%)
 Frame = +3

Query: 463 FCLDFSHNGRILAAACASRDGYPIILYEIPSGRFMREL-CGHLNIIYDLDWSKDDR---- 517
            C+D S +  ++ + CA        ++ + SG+      C       D D S +      
Sbjct: 381 LCVDCSADNALIMSGCADATAK---VFNVSSGKLXSAFNCAASQDSQDKDNSVESVAFCP 551

Query: 518 ---YLVTSSSDGTARVWKNEINSTSTFRVLPHPSFVYTAKFHPATRELVVTGCYDSMIRI 574
              Y  T+++ G+ +VW  ++ ++       HP  V   ++  +T  L+ T C D ++R+
Sbjct: 552 VSPYAATATNSGSVQVW--DLPTSVARHSFQHPEGVCKLQWSSST-ALLYTACLDGVMRV 722

Query: 575 WKIDAREDAAILV 587
           W  DAR  A+  V
Sbjct: 723 W--DARSGASKAV 755

 Score = 33.9 bits (76), Expect = 0.39,   Method: Compositional matrix adjust.
 Identities = 27/82 (32%), Positives = 43/82 (52%), Gaps = 2/82 (2%)
 Frame = +3

Query: 465 LDFSHNGRILAAACASRDGYPIILYEIPSGRFMRELCGHL--NIIYDLDWSKDDRYLVTS 522
           L +S +  +L  AC   DG  + +++  SG     L GH   + I D D ++D   LV+ 
Sbjct: 660 LQWSSSTALLYTAC--LDGV-MRVWDARSGASKAVLTGHARNSCILDFDVTRDGTCLVSG 830

Query: 523 SSDGTARVWKNEINSTSTFRVL 544
           S DGTARV   +++S +   V+
Sbjct: 831 SEDGTARVLT*DLHSRNFVSVI 896

 Score = 32.3 bits (72), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 40/170 (23%), Positives = 68/170 (40%), Gaps = 8/170 (4%)
 Frame = +3

Query: 558 ATRELVVTGCYDSMIRIWKIDARE-----DAAILVRQLDVHKSFVNSICFDDEGHHMYSG 612
           A   L+++GC D+  +++ + + +     + A      D   S V S+ F     +  + 
Sbjct: 399 ADNALIMSGCADATAKVFNVSSGKLXSAFNCAASQDSQDKDNS-VESVAFCPVSPYAATA 575

Query: 613 DCIGVIVVWDTYVKVNDVQHSVRHWTINKEIKETEFRGVPISYLEVHPNGKRLLIHTK-- 670
              G + VWD    V   +HS +H               P    ++  +    L++T   
Sbjct: 576 TNSGSVQVWDLPTSV--ARHSFQH---------------PEGVCKLQWSSSTALLYTACL 704

Query: 671 DSTLRIMDLRILAARK-FVGAANYREKIHSTLTPCGTLLFSGSEDGIVYV 719
           D  +R+ D R  A++    G A     +   +T  GT L SGSEDG   V
Sbjct: 705 DGVMRVWDARSGASKAVLTGHARNSCILDFDVTRDGTCLVSGSEDGTARV 854
>30740
          Length = 488

 Score = 35.8 bits (81), Expect = 0.088,   Method: Compositional matrix adjust.
 Identities = 14/48 (29%), Positives = 26/48 (54%)
 Frame = +2

Query: 903 PPPMVVALYDYTASRSDELTIHRGDIIRVYFKDNEDWWYGSVRKGQEG 950
           P   ++  YD++    ++L   +GDI+ +  KD E+WW    + G+ G
Sbjct: 179 PREKLMGKYDFSGRDPEDLPFSKGDILELISKDEEEWWTARDKHGRVG 322
>19863
          Length = 502

 Score = 35.4 bits (80), Expect = 0.13,   Method: Composition-based stats.
 Identities = 15/49 (30%), Positives = 30/49 (61%)
 Frame = +1

Query: 486 IILYEIPSGRFMRELCGHLNIIYDLDWSKDDRYLVTSSSDGTARVWKNE 534
           I+++++ +G     L GH   + D+ +S+D  +L++ S+D T R+W  E
Sbjct: 43  IVVWDVENGVQKLRLQGHAGWVNDVHFSQDQCWLLSCSNDNTVRIWNIE 189
>31384
          Length = 474

 Score = 35.4 bits (80), Expect = 0.13,   Method: Composition-based stats.
 Identities = 16/44 (36%), Positives = 25/44 (56%)
 Frame = -1

Query: 503 HLNIIYDLDWSKDDRYLVTSSSDGTARVWKNEINSTSTFRVLPH 546
           H   + D+DWS D   + T+S D TA+VW  ++NS    ++  H
Sbjct: 138 HTGPVLDVDWSDDGTKVFTASCDKTAKVW--DLNSNQCMQIAQH 13

 Score = 29.3 bits (64), Expect = 8.4,   Method: Composition-based stats.
 Identities = 24/112 (21%), Positives = 48/112 (42%), Gaps = 8/112 (7%)
 Frame = -1

Query: 519 LVTSSSDGTARVWKNEINSTST-----FRVLPHPS-FVYTAKFHPAT--RELVVTGCYDS 570
           L  +SS G + V+ +   + +T     F V   P   V   KF P       +++G +D+
Sbjct: 378 LFGTSSFGQSNVFGSTAPAANTNPMKDFEVTSPPDDSVSCLKFSPGALPSTFLISGSWDN 199

Query: 571 MIRIWKIDAREDAAILVRQLDVHKSFVNSICFDDEGHHMYSGDCIGVIVVWD 622
            +  W++  ++    + +    H   V  + + D+G  +++  C     VWD
Sbjct: 198 KVSCWEV--QQSGQTIPKAQQTHTGPVLDVDWSDDGTKVFTASCDKTAKVWD 49
>26939
          Length = 388

 Score = 35.0 bits (79), Expect = 0.15,   Method: Compositional matrix adjust.
 Identities = 19/60 (31%), Positives = 32/60 (53%), Gaps = 1/60 (1%)
 Frame = +2

Query: 517 RYLVTSSSDGTARVWKNEINSTSTFRVL-PHPSFVYTAKFHPATRELVVTGCYDSMIRIW 575
           +YLV++S D T RVW  ++ +    + L  H  F  +  FH A    V++G  D  +++W
Sbjct: 5   KYLVSASDDKTIRVW--DLRNKRCMKTLYAHQHFCTSIDFHKA-HPYVISGSVDQTVKVW 175
>13278
          Length = 870

 Score = 35.0 bits (79), Expect = 0.17,   Method: Compositional matrix adjust.
 Identities = 21/94 (22%), Positives = 45/94 (47%), Gaps = 8/94 (8%)
 Frame = +1

Query: 550 VYTAKFHPA--------TRELVVTGCYDSMIRIWKIDAREDAAILVRQLDVHKSFVNSIC 601
           +YT K+ P         T  ++ +  +DS +R+W++    +  + +  L  H+  V S+ 
Sbjct: 58  IYTIKWSPTGPGTSNPNTSLILASASFDSTVRLWEV----ERGLCLHTLTKHQEPVYSVA 225

Query: 602 FDDEGHHMYSGDCIGVIVVWDTYVKVNDVQHSVR 635
           F  +G ++ SG     + +W+  V+   + HS +
Sbjct: 226 FSPDGKYLASGSFDKCVHIWN--VQTGSLVHSYK 321

 Score = 33.1 bits (74), Expect = 0.58,   Method: Compositional matrix adjust.
 Identities = 25/75 (33%), Positives = 38/75 (50%), Gaps = 3/75 (4%)
 Frame = +1

Query: 660 PNGKRLLIHTK-DSTLRIMDL-RILAARKFVGAANYREKIHS-TLTPCGTLLFSGSEDGI 716
           PN   +L     DST+R+ ++ R L          ++E ++S   +P G  L SGS D  
Sbjct: 103 PNTSLILASASFDSTVRLWEVERGLCLHTL---TKHQEPVYSVAFSPDGKYLASGSFDKC 273

Query: 717 VYVWNPETGEQVAMY 731
           V++WN +TG  V  Y
Sbjct: 274 VHIWNVQTGSLVHSY 318

 Score = 32.3 bits (72), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 19/64 (29%), Positives = 30/64 (46%)
 Frame = +1

Query: 474 LAAACASRDGYPIILYEIPSGRFMRELCGHLNIIYDLDWSKDDRYLVTSSSDGTARVWKN 533
           L  A AS D   + L+E+  G  +  L  H   +Y + +S D +YL + S D    +W  
Sbjct: 115 LILASASFDS-TVRLWEVERGLCLHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNV 291

Query: 534 EINS 537
           +  S
Sbjct: 292 QTGS 303
>01462
          Length = 995

 Score = 34.7 bits (78), Expect = 0.21,   Method: Compositional matrix adjust.
 Identities = 29/98 (29%), Positives = 48/98 (48%)
 Frame = +2

Query: 447 IPNKHLFSLNAGERGCFCLDFSHNGRILAAACASRDGYPIILYEIPSGRFMRELCGHLNI 506
           +P   +FS NA E     +D     R L A    R    I +++I +G+++  + GH + 
Sbjct: 167 LPRSGVFS-NA-EVNSIAVDEKMGTRRLYAGAGDRK---IHVWDIEAGQYLNAMEGHKDY 331

Query: 507 IYDLDWSKDDRYLVTSSSDGTARVWKNEINSTSTFRVL 544
           I+ +    D +  V++S DGT R+W    +ST T   L
Sbjct: 332 IHKVVMKNDAQECVSASEDGTVRMWDIR-SSTETVHCL 442
>38177
          Length = 430

 Score = 33.9 bits (76), Expect = 0.31,   Method: Composition-based stats.
 Identities = 20/84 (23%), Positives = 38/84 (45%)
 Frame = +3

Query: 464 CLDFSHNGRILAAACASRDGYPIILYEIPSGRFMRELCGHLNIIYDLDWSKDDRYLVTSS 523
           CL ++  GR L    +S +     L+   +  F   L  H   +  + WS  D+++VT+ 
Sbjct: 3   CLAWTPEGRRLVTGASSGE---FTLWNGLTFNFETILQAHDVSVRAMRWSNHDQWMVTAD 173

Query: 524 SDGTARVWKNEINSTSTFRVLPHP 547
             G  + W++ +N+   F+    P
Sbjct: 174 HSGYIKYWQSNMNNVKMFQGHKEP 245
>16105
          Length = 960

 Score = 33.9 bits (76), Expect = 0.32,   Method: Compositional matrix adjust.
 Identities = 21/87 (24%), Positives = 38/87 (43%), Gaps = 7/87 (8%)
 Frame = -2

Query: 502 GHLNIIYDLDWS-KDDRYLVTSSSDGTARVWKNEINSTSTFRVLPHPSFVYTAK------ 554
           GH   + D+ W   +D  + ++S D T +VW+   +   T    P    V   K      
Sbjct: 581 GHKGAVLDIQWCPHNDNVIASASDDCTVKVWQIPDSGLVTNLTDPVVDLVGHQKRCCLIV 402

Query: 555 FHPATRELVVTGCYDSMIRIWKIDARE 581
           +HP+ + ++V+   D+ I  W +   E
Sbjct: 401 WHPSAQNVLVSAGADNKILFWNVGTGE 321
>05642
          Length = 445

 Score = 33.9 bits (76), Expect = 0.35,   Method: Composition-based stats.
 Identities = 24/70 (34%), Positives = 36/70 (51%), Gaps = 2/70 (2%)
 Frame = -1

Query: 682 LAARKFVGAANYREKIHSTLTPCGTLLFSGSEDGIVYVWNPETGEQVAMYSDLPFKST-- 739
           ++A  F G  + + KI S L    TL+ SGSEDG VY W+     +  +   L  K+T  
Sbjct: 442 VSAVWFTGHKHSQYKIDSCLNNEDTLVVSGSEDGKVYFWDL---VEAKLVDTLDHKTTRP 272

Query: 740 IRDISYHPLE 749
           +  +S+H  E
Sbjct: 271 VHSLSFHHAE 242
>15115
          Length = 443

 Score = 33.9 bits (76), Expect = 0.35,   Method: Composition-based stats.
 Identities = 17/45 (37%), Positives = 22/45 (48%)
 Frame = -2

Query: 913 YTASRSDELTIHRGDIIRVYFKDNEDWWYGSVRKGQEGFFPANHV 957
           + A    E+T    DII    + +E WW G    G  G FPAN+V
Sbjct: 433 HQAGDDTEITFDPDDIITNIDQIDEGWWQGFAPDGSYGMFPANYV 299
>03156
          Length = 1014

 Score = 33.9 bits (76), Expect = 0.39,   Method: Compositional matrix adjust.
 Identities = 24/97 (24%), Positives = 46/97 (47%)
 Frame = +1

Query: 479 ASRDGYPIILYEIPSGRFMRELCGHLNIIYDLDWSKDDRYLVTSSSDGTARVWKNEINST 538
           ASRD   I +++  +   +R+  GH  ++  +  + D+  L + S D T R+W  E  + 
Sbjct: 109 ASRD-KTIKMWQRGNSHSIRDFIGHDMVVTAIHLNTDNTLLCSGSRDNTVRIWDVETGAC 285

Query: 539 STFRVLPHPSFVYTAKFHPATRELVVTGCYDSMIRIW 575
                +P  + V   K+ P +  L++    D  +RI+
Sbjct: 286 LRQNNIPQ-NLVTDVKWLPGS-HLIIQAGEDKEVRIY 390

 Score = 32.3 bits (72), Expect = 0.96,   Method: Compositional matrix adjust.
 Identities = 21/70 (30%), Positives = 37/70 (52%)
 Frame = +1

Query: 683 AARKFVGAANYREKIHSTLTPCGTLLFSGSEDGIVYVWNPETGEQVAMYSDLPFKSTIRD 742
           + R F+G       IH  L    TLL SGS D  V +W+ ETG  +   +++P ++ + D
Sbjct: 157 SIRDFIGHDMVVTAIH--LNTDNTLLCSGSRDNTVRIWDVETGACLRQ-NNIP-QNLVTD 324

Query: 743 ISYHPLENMV 752
           + + P  +++
Sbjct: 325 VKWLPGSHLI 354
>37180
          Length = 681

 Score = 33.5 bits (75), Expect = 0.45,   Method: Composition-based stats.
 Identities = 24/78 (30%), Positives = 37/78 (47%)
 Frame = +1

Query: 500 LCGHLNIIYDLDWSKDDRYLVTSSSDGTARVWKNEINSTSTFRVLPHPSFVYTAKFHPAT 559
           L GH   + D+      R +VTSS D T R+W    ++        H   V +A F  A+
Sbjct: 7   LNGHDQELSDVHAHPTQRLVVTSSKDMTFRLWDFRDSALLVNVFQGHTQPVTSAVF--AS 180

Query: 560 RELVVTGCYDSMIRIWKI 577
            + VV+G  D  +R+W +
Sbjct: 181 GDKVVSGSDDRTVRVWDM 234

 Score = 33.5 bits (75), Expect = 0.48,   Method: Composition-based stats.
 Identities = 21/71 (29%), Positives = 35/71 (49%), Gaps = 2/71 (2%)
 Frame = +1

Query: 653 ISYLEVHPNGKRLLIHTKDSTLRIMDLR--ILAARKFVGAANYREKIHSTLTPCGTLLFS 710
           +S +  HP  + ++  +KD T R+ D R   L    F G   + + + S +   G  + S
Sbjct: 28  LSDVHAHPTQRLVVTSSKDMTFRLWDFRDSALLVNVFQG---HTQPVTSAVFASGDKVVS 198

Query: 711 GSEDGIVYVWN 721
           GS+D  V VW+
Sbjct: 199 GSDDRTVRVWD 231
>34005
          Length = 456

 Score = 33.5 bits (75), Expect = 0.49,   Method: Composition-based stats.
 Identities = 32/123 (26%), Positives = 51/123 (41%), Gaps = 8/123 (6%)
 Frame = +1

Query: 498 RELCGHLNIIYDLDWSKDDRYLVTSSSDGTARVWKNEINSTSTFRVLP------HPSFVY 551
           +E+CG       L WS D  +L + S+D +  +W    +ST    V P      H + V 
Sbjct: 115 QEVCG-------LSWSPDATFLASGSNDNSVNIW----DSTLGMDVPPLHTLTSHQAAVK 261

Query: 552 TAKFHPATRELVVT--GCYDSMIRIWKIDAREDAAILVRQLDVHKSFVNSICFDDEGHHM 609
              + P    ++ T  G  D  IR W      +    V+ +D  +S V S+ +  E   +
Sbjct: 262 AVAWCPWQTRMLATGGGTNDRHIRFWNT----NTGACVKAVDT-QSQVCSVLWCKEHREL 426

Query: 610 YSG 612
            SG
Sbjct: 427 VSG 435
>11915
          Length = 737

 Score = 33.1 bits (74), Expect = 0.54,   Method: Composition-based stats.
 Identities = 14/48 (29%), Positives = 30/48 (62%), Gaps = 1/48 (2%)
 Frame = +1

Query: 486 IILYEIPSGRFMRELCGHLNIIYDLDWSKDDRY-LVTSSSDGTARVWK 532
           I L+   +G+ + E+  H   ++DL ++ D+   L+++S DGT ++W+
Sbjct: 478 IKLWNCETGKLLIEMMDHKATVHDLHFAADNSLCLMSASHDGTVKLWE 621
>27465
          Length = 658

 Score = 32.7 bits (73), Expect = 0.81,   Method: Compositional matrix adjust.
 Identities = 19/81 (23%), Positives = 37/81 (45%), Gaps = 1/81 (1%)
 Frame = -1

Query: 496 FMRELCGHLNIIYDLDWSKDDRYLVTSSSDGTARVWKNEINSTSTFRVLP-HPSFVYTAK 554
             + L  H+  + ++ ++K     +T S D T ++W  +  S      L  H + VY   
Sbjct: 385 LFKVLRAHILPLTNVAFNKSGSSFITGSYDRTCKIW--DTASAEELHTLEGHRNVVYAIA 212

Query: 555 FHPATRELVVTGCYDSMIRIW 575
           F+    + V+TG +D   ++W
Sbjct: 211 FNNPFGDKVITGSFDKTCKLW 149
>02090
          Length = 1841

 Score = 32.7 bits (73), Expect = 0.82,   Method: Compositional matrix adjust.
 Identities = 21/77 (27%), Positives = 37/77 (48%)
 Frame = -3

Query: 455  LNAGERGCFCLDFSHNGRILAAACASRDGYPIILYEIPSGRFMRELCGHLNIIYDLDWSK 514
            L +    C+ L  S +G++  + C+  DG  I ++++ +   +R+  GH +    +D S 
Sbjct: 1638 LTSSAPACYALAISPDGKVCFSCCS--DG-NIAVWDLHNQTLVRQFQGHTDGASCIDISP 1468

Query: 515  DDRYLVTSSSDGTARVW 531
            D   L T   D T R W
Sbjct: 1467 DGTKLWTGGLDNTVRSW 1417
>02147
          Length = 1547

 Score = 32.7 bits (73), Expect = 0.88,   Method: Compositional matrix adjust.
 Identities = 14/61 (22%), Positives = 29/61 (47%)
 Frame = +2

Query: 478 CASRDGYPIILYEIPSGRFMRELCGHLNIIYDLDWSKDDRYLVTSSSDGTARVWKNEINS 537
            A  + + +  ++  +G+ +    GH   ++ + +S D     + S DGT R+W+  I  
Sbjct: 716 VAGGEDFKMYKFDYETGKEIESFKGHFGPVHCVRFSPDGELYASGSEDGTLRLWQTTIGR 895

Query: 538 T 538
           T
Sbjct: 896 T 898
>30482
          Length = 610

 Score = 32.3 bits (72), Expect = 0.92,   Method: Composition-based stats.
 Identities = 17/49 (34%), Positives = 28/49 (57%), Gaps = 4/49 (8%)
 Frame = +3

Query: 909 ALYDYTASRSDELTIHRGDIIRVYFKDNE----DWWYGSVRKGQEGFFP 953
           AL+ + +   DEL I+ GD I V+   +E    +W+ G  + G+ G+FP
Sbjct: 135 ALFPFESRSEDELNINTGDDIWVWDVPSEPGMEEWFKGETKDGKVGWFP 281
>27681
          Length = 465

 Score = 32.3 bits (72), Expect = 1.1,   Method: Composition-based stats.
 Identities = 28/95 (29%), Positives = 40/95 (42%), Gaps = 12/95 (12%)
 Frame = +2

Query: 512 WSKDDRYLVTSSSDGTARVWK--NEINSTSTFRVLPH---------PSFV-YTAKFHPAT 559
           W+  +  L + S D TAR+W   +E  + +   VL H         PS    T+    + 
Sbjct: 17  WNPTNDLLASGSGDSTARIWNMTSETPNNANQLVLRHCIQKGGTEVPSNKDVTSLDWNSE 196

Query: 560 RELVVTGCYDSMIRIWKIDAREDAAILVRQLDVHK 594
             L+ TG YD   R+W+ D       LV  L  HK
Sbjct: 197 GTLLATGSYDGYARLWRTDGH-----LVNTLGQHK 286

 Score = 30.8 bits (68), Expect = 3.3,   Method: Composition-based stats.
 Identities = 11/28 (39%), Positives = 17/28 (60%)
 Frame = +2

Query: 507 IYDLDWSKDDRYLVTSSSDGTARVWKNE 534
           +  LDW+ +   L T S DG AR+W+ +
Sbjct: 170 VTSLDWNSEGTLLATGSYDGYARLWRTD 253
>15972
          Length = 1069

 Score = 32.3 bits (72), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 30/129 (23%), Positives = 56/129 (43%)
 Frame = +3

Query: 485 PIILYEIPSGRFMRELCGHLNIIYDLDWSKDDRYLVTSSSDGTARVWKNEINSTSTFRVL 544
           P +  E P G   R   GH   +  L      +  +T S D T R+W N +N    F + 
Sbjct: 180 PCVCGECPPG*PERTFSGHKGPVRHLAVHPSGKLTLTVSQDRTLRLWNN-MNGRIAF-IS 353

Query: 545 PHPSFVYTAKFHPATRELVVTGCYDSMIRIWKIDAREDAAILVRQLDVHKSFVNSICFDD 604
                  + ++ P     VV   + S + ++ ++++     L+R +D  ++ VNS+ F  
Sbjct: 354 NMKEAAESVRWAPGGLYYVVA--FRSHLDVYSVESKG----LLRSIDTSQT-VNSVGFVT 512

Query: 605 EGHHMYSGD 613
           +   +Y G+
Sbjct: 513 DTVLVYGGE 539

 Score = 30.8 bits (68), Expect = 2.7,   Method: Compositional matrix adjust.
 Identities = 15/33 (45%), Positives = 22/33 (66%), Gaps = 3/33 (9%)
 Frame = +3

Query: 652 PISYLEVHPNGKRLLIHTKDSTLRI---MDLRI 681
           P+ +L VHP+GK  L  ++D TLR+   M+ RI
Sbjct: 243 PVRHLAVHPSGKLTLTVSQDRTLRLWNNMNGRI 341
>14500
          Length = 1238

 Score = 32.0 bits (71), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 14/47 (29%), Positives = 28/47 (59%)
 Frame = +3

Query: 486 IILYEIPSGRFMRELCGHLNIIYDLDWSKDDRYLVTSSSDGTARVWK 532
           +I+++ P+   + EL GH   +  +  S D   +V++++D T R+WK
Sbjct: 411 LIIWKYPAMSRVAELTGHTARVLHMAMSPDGETVVSAAADETLRLWK 551

 Score = 30.4 bits (67), Expect = 4.1,   Method: Composition-based stats.
 Identities = 15/42 (35%), Positives = 22/42 (52%), Gaps = 3/42 (7%)
 Frame = +2

Query: 500 LCGHLNIIYDLDWSKDDRYLVTSSSDGTARVWKNEI---NST 538
           L GH   +  L WS D +YL + ++D    VW  ++   NST
Sbjct: 47  LSGHSQEVCGLRWSPDGKYLASGANDNLLCVWPAQVTGGNST 172
>31054
          Length = 392

 Score = 32.0 bits (71), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 15/43 (34%), Positives = 23/43 (53%)
 Frame = -2

Query: 489 YEIPSGRFMRELCGHLNIIYDLDWSKDDRYLVTSSSDGTARVW 531
           ++ P G F++ L GH  II  L     D  LV+ + +GT  +W
Sbjct: 334 WKFPDGNFIQNLSGHNAIINTLA-VNSDGVLVSGADNGTMHLW 209
>27525
          Length = 828

 Score = 31.6 bits (70), Expect = 1.7,   Method: Composition-based stats.
 Identities = 26/95 (27%), Positives = 36/95 (37%), Gaps = 4/95 (4%)
 Frame = +2

Query: 454 SLNAGERGCFCLDFSHNGRILAAACASRDGYPIILYEIPSGRFMRELCGHL----NIIYD 509
           S   G+     + FS +G  LA  C   DG+  +      G   R+    L      I  
Sbjct: 53  SFQVGQAQINAISFSPDGSQLAVGC--HDGFVHVYVVHEDGLVFRQKSAALRYNSTFIMH 226

Query: 510 LDWSKDDRYLVTSSSDGTARVWKNEINSTSTFRVL 544
           LDWS D RYL  +  D     W+ +     + R L
Sbjct: 227 LDWSSDCRYLQCTLGDYELVFWEVQNMKKQSGRAL 331
>29912
          Length = 510

 Score = 31.6 bits (70), Expect = 1.8,   Method: Composition-based stats.
 Identities = 21/77 (27%), Positives = 33/77 (42%), Gaps = 4/77 (5%)
 Frame = +3

Query: 500 LCGHLNIIYDLDWSKDDRYLVTSSSDGTARVWKNEI---NSTSTFRVLP-HPSFVYTAKF 555
           L GH   +  L WS D +YL + ++D    VW  ++   NST        H + V    +
Sbjct: 246 LSGHSQEVCGLRWSPDGKYLASGANDNLLCVWPAQVTGGNSTQPLHTFSQHQAAVKALAW 425

Query: 556 HPATRELVVTGCYDSMI 572
            P     + +G  D +I
Sbjct: 426 CPWQPSXLASGGGDVLI 476
>21105
          Length = 650

 Score = 31.6 bits (70), Expect = 1.9,   Method: Compositional matrix adjust.
 Identities = 17/53 (32%), Positives = 26/53 (49%), Gaps = 2/53 (3%)
 Frame = +1

Query: 703 PCGTLLFSGSEDGIVYVWN--PETGEQVAMYSDLPFKSTIRDISYHPLENMVA 753
           P G  L SGS D  + +WN   +T  Q        F  +I D+++HP +  +A
Sbjct: 220 PNGLYLLSGSHDCSIRLWNLDSKTCVQEITSHRKKFDESIHDVAFHPQKPYIA 378
>11228
          Length = 2155

 Score = 31.2 bits (69), Expect = 2.0,   Method: Compositional matrix adjust.
 Identities = 21/59 (35%), Positives = 29/59 (49%), Gaps = 2/59 (3%)
 Frame = -2

Query: 901  VDPPPMVVALYDY-TASRSDELTIHRGDIIRVYFKDNEDW-WYGSVRKGQEGFFPANHV 957
            VD    VVA+  Y  A+ SDEL+  +GD+  V  +  + W W    R  + G  PA  V
Sbjct: 1683 VDDRRRVVAMLSYRKATDSDELSFCKGDVFVVQNEMEDGWLWVTCERTKESGLVPAPFV 1507
>03395
          Length = 2795

 Score = 31.2 bits (69), Expect = 2.1,   Method: Compositional matrix adjust.
 Identities = 37/212 (17%), Positives = 77/212 (36%), Gaps = 10/212 (4%)
 Frame = +2

Query: 519 LVTSSSDGTARVW---KNEINSTSTFRVLP----HPSFVYTAKFHPATRELVVTGCYDSM 571
           LV+   +G  RVW   K+ +   +   ++     H   V   + H   R   V+   D  
Sbjct: 41  LVSGGGEGQVRVWDIVKDMLTGKTRGDLVANMKEHKGKVTAIQIHTNDR-CCVSASTDGS 217

Query: 572 IRIWKIDAREDAAILVRQLDVHKSFVNSICFDDEGHHMYSGDCIGVIVVWDTYVKVNDVQ 631
             IW +     + I++       +    +CF  +                D ++  +   
Sbjct: 218 TIIWDLITNTRSQIVLAN-----TLFKCVCFGGK----------------DLHILTSGTD 334

Query: 632 HSVRHWTINKEIKETEFRGV---PISYLEVHPNGKRLLIHTKDSTLRIMDLRILAARKFV 688
           H + +W +       E  G     I+ +++  +G+ +L   +DS L++            
Sbjct: 335 HKIGYWEVGDGGLLRELEGSQTGAINTIDIDRDGQTILTGGEDSLLKLWRYN-EGEVTHT 511

Query: 689 GAANYREKIHSTLTPCGTLLFSGSEDGIVYVW 720
           G  +  +   + + P    + SG EDG +++W
Sbjct: 512 GIGHSNQITKARICPNRHYIVSGGEDGALHIW 607
>33180
          Length = 460

 Score = 31.2 bits (69), Expect = 2.6,   Method: Compositional matrix adjust.
 Identities = 20/78 (25%), Positives = 36/78 (46%), Gaps = 1/78 (1%)
 Frame = -2

Query: 546 HPSFVYTAKFHPATRELVVTGCYDSMIRIWKIDAREDAAILVRQLDVHKSFVNSICF-DD 604
           H   +++  F     E +V G  D  + ++  ++ +       ++D H   VN++ F DD
Sbjct: 456 HSFCIFSLMFSSDNTE-IVGGANDGCLYVYDRESNQ----RTLKIDAHDDDVNAVAFADD 292

Query: 605 EGHHMYSGDCIGVIVVWD 622
               +YSG   G+  VWD
Sbjct: 291 SSQILYSGGDDGLCKVWD 238
>21921
          Length = 1341

 Score = 30.8 bits (68), Expect = 2.6,   Method: Compositional matrix adjust.
 Identities = 18/73 (24%), Positives = 33/73 (45%)
 Frame = -1

Query: 502 GHLNIIYDLDWSKDDRYLVTSSSDGTARVWKNEINSTSTFRVLPHPSFVYTAKFHPATRE 561
           GH  I+  +      ++LV+ S DGT R W  E++S    + L     V +  ++P    
Sbjct: 489 GHTGIVRSICPDPTGQWLVSGSDDGTIRFW--EVSSGRCMKTLQVGGCVTSVAWNPNPSL 316

Query: 562 LVVTGCYDSMIRI 574
            VV    ++ + +
Sbjct: 315 CVVAATLNTTVLL 277
>19140
          Length = 573

 Score = 30.4 bits (67), Expect = 4.3,   Method: Compositional matrix adjust.
 Identities = 16/48 (33%), Positives = 27/48 (56%), Gaps = 1/48 (2%)
 Frame = -3

Query: 497 MRELCGHLNIIYDLDWSKDDRYLVTSSSDGTARVWK-NEINSTSTFRV 543
           + +L GH + +  L  ++D    ++ SSDGT R+W   +    +TFRV
Sbjct: 508 LMKLKGHTDNVKALVLNRDGTQCLSGSSDGTIRLWSLGQQRCVATFRV 365
>26032
          Length = 465

 Score = 30.0 bits (66), Expect = 4.9,   Method: Compositional matrix adjust.
 Identities = 16/46 (34%), Positives = 23/46 (50%)
 Frame = +2

Query: 912 DYTASRSDELTIHRGDIIRVYFKDNEDWWYGSVRKGQEGFFPANHV 957
           D+     DEL   + DII +  + +E  W G +  G  G+FPA  V
Sbjct: 29  DFERHDDDELGFRKNDIITLISQKDEHCWIGEL-NGLRGWFPAKFV 163
>11322
          Length = 1521

 Score = 29.6 bits (65), Expect = 5.9,   Method: Composition-based stats.
 Identities = 19/59 (32%), Positives = 27/59 (45%)
 Frame = +2

Query: 840  VIRSCAAKVNKNLSMTSPPPGPAKKPRVKQSFVLTTDEIIHQFGLPQTAFISIERGPFV 898
            V+  C A   +NL  +SP   P + P +K +      +  H F LP TA     R PF+
Sbjct: 1364 VLXXCLAPXRRNLWQSSP---PLQSPALKTALSTQAKDTGHPFDLPLTA-----RRPFI 1516
>38362
          Length = 1255

 Score = 29.6 bits (65), Expect = 6.8,   Method: Compositional matrix adjust.
 Identities = 14/43 (32%), Positives = 24/43 (55%), Gaps = 1/43 (2%)
 Frame = -1

Query: 503 HLNIIYDLDWSKDDRYLVTSSSDGTARVWK-NEINSTSTFRVL 544
           H + ++ + W+     LV+S +DG  R+WK N + S +   VL
Sbjct: 619 HDSQVWRVSWNVTGTILVSSGADGCVRIWKANYLGSWACISVL 491
>30297
          Length = 822

 Score = 29.3 bits (64), Expect = 8.6,   Method: Compositional matrix adjust.
 Identities = 13/40 (32%), Positives = 24/40 (60%)
 Frame = -1

Query: 502 GHLNIIYDLDWSKDDRYLVTSSSDGTARVWKNEINSTSTF 541
           GH+  +  LD  + ++ L+TS++D T R+W  + +   TF
Sbjct: 234 GHVESVSCLDLVEQNKVLLTSAADCTVRMWTTDGHYIGTF 115
>08480
          Length = 698

 Score = 29.3 bits (64), Expect = 8.9,   Method: Compositional matrix adjust.
 Identities = 15/40 (37%), Positives = 21/40 (52%), Gaps = 5/40 (12%)
 Frame = -1

Query: 906 MVVALYDYTASR-----SDELTIHRGDIIRVYFKDNEDWW 940
            V AL+DY  S+     S  L  H GDI+ V    +++WW
Sbjct: 449 FVRALFDYEPSKDSGLPSRGLWFHYGDILHVTNASDDEWW 330
>02960
          Length = 1577

 Score = 29.3 bits (64), Expect = 9.2,   Method: Compositional matrix adjust.
 Identities = 20/82 (24%), Positives = 37/82 (45%), Gaps = 2/82 (2%)
 Frame = +2

Query: 507  IYDLDWSKDDRYLVTSSSDGTARVWKNEINSTSTFRV--LPHPSFVYTAKFHPATRELVV 564
            + D+ +S     L+T S+D   R+     +   T +     H  +V    + P    L +
Sbjct: 1088 VLDVAYSPLSHMLITGSADRHVRLVDPRCSEGETVKCAFTSHTGWVTGVDWSPTREHLFL 1267

Query: 565  TGCYDSMIRIWKIDAREDAAIL 586
            +G YD+++++W  D R   A L
Sbjct: 1268 SGSYDNVLKLW--DTRSPKATL 1327
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|26553441|ref|NP_082319.1| hypothetical protein
LOC52846 [Mus musculus]
         (505 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

37264                                                                  64   1e-10
07961                                                                  28   6.9  
18053                                                                  28   7.1  
>37264
          Length = 184

 Score = 64.3 bits (155), Expect = 1e-10,   Method: Composition-based stats.
 Identities = 28/34 (82%), Positives = 32/34 (94%)
 Frame = +2

Query: 466 FIEVQAFCIEFSRIREAAGLFRLLKTLDTGETPS 499
           FIEVQAFCIEFSRIREAAGLFRLLK+LD+ + P+
Sbjct: 5   FIEVQAFCIEFSRIREAAGLFRLLKSLDSVDNPT 106
>07961
          Length = 1204

 Score = 28.5 bits (62), Expect = 6.9,   Method: Compositional matrix adjust.
 Identities = 11/33 (33%), Positives = 20/33 (60%)
 Frame = +2

Query: 427 CISTCEQIKDKYMQNRLVRLVCVFLQSLIRNKI 459
           C   CE+ +D+Y++  +   VCV   +L+R K+
Sbjct: 176 CACVCERERDEYVRXCMYMCVCVRFVTLVREKV 274
>18053
          Length = 456

 Score = 28.5 bits (62), Expect = 7.1,   Method: Composition-based stats.
 Identities = 18/59 (30%), Positives = 34/59 (57%), Gaps = 5/59 (8%)
 Frame = -2

Query: 418 EFIHLYISNCISTCE-QIKDK----YMQNRLVRLVCVFLQSLIRNKIINVQDLFIEVQA 471
           EF+  +++NC+ST E Q  +     YM  +L R++ V + + I   I+ VQ + + ++A
Sbjct: 227 EFLQCFLTNCLSTDEPQYFNTHMYVYMDLQLFRIIYVHICAYIFIYIVKVQ*IKVAIEA 51
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6678551|ref|NP_033523.1| vesicle-associated membrane
protein 2 [Mus musculus]
         (116 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

02964                                                                  60   2e-10
04498                                                                  60   3e-10
>02964
          Length = 832

 Score = 60.1 bits (144), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 24/60 (40%), Positives = 44/60 (73%)
 Frame = -3

Query: 36  QAQVDEVVDIMRVNVDKVLERDQKLSELDDRADALQAGASQFETSAAKLKRKYWWKNLKM 95
           Q+QV+EV  +M  N++KV+ER  +L +L D+ + L+A A  F+ ++ ++++K+WW+N KM
Sbjct: 725 QSQVNEVKGVMTQNIEKVMERGDRLEDLMDKTEELEASAHNFQKTSRRIRKKFWWRNKKM 546
>04498
          Length = 1353

 Score = 59.7 bits (143), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 24/60 (40%), Positives = 44/60 (73%)
 Frame = +3

Query: 36  QAQVDEVVDIMRVNVDKVLERDQKLSELDDRADALQAGASQFETSAAKLKRKYWWKNLKM 95
           Q+QV+EV  +M  N++KV+ER  +L +L D+ + L+A A  F+ ++ ++++K+WW+N KM
Sbjct: 105 QSQVNEVKGVMTQNIEKVMERGDRLEDLMDKTEELEASAHNFQKTSRRIRKKFWWRNKKM 284
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6678553|ref|NP_033524.1| vesicle-associated membrane
protein 3 [Mus musculus]
         (103 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

02964                                                                  60   2e-10
04498                                                                  60   3e-10
16746                                                                  55   8e-09
06063                                                                  26   4.5  
03298                                                                  25   8.7  
>02964
          Length = 832

 Score = 60.1 bits (144), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 24/60 (40%), Positives = 44/60 (73%)
 Frame = -3

Query: 23  QNQVDEVVDIMRVNVDKVLERDQKLSELDDRADALQAGASQFETSAAKLKRKYWWKNCKM 82
           Q+QV+EV  +M  N++KV+ER  +L +L D+ + L+A A  F+ ++ ++++K+WW+N KM
Sbjct: 725 QSQVNEVKGVMTQNIEKVMERGDRLEDLMDKTEELEASAHNFQKTSRRIRKKFWWRNKKM 546
>04498
          Length = 1353

 Score = 59.7 bits (143), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 24/60 (40%), Positives = 44/60 (73%)
 Frame = +3

Query: 23  QNQVDEVVDIMRVNVDKVLERDQKLSELDDRADALQAGASQFETSAAKLKRKYWWKNCKM 82
           Q+QV+EV  +M  N++KV+ER  +L +L D+ + L+A A  F+ ++ ++++K+WW+N KM
Sbjct: 105 QSQVNEVKGVMTQNIEKVMERGDRLEDLMDKTEELEASAHNFQKTSRRIRKKFWWRNKKM 284
>16746
          Length = 340

 Score = 54.7 bits (130), Expect = 8e-09,   Method: Compositional matrix adjust.
 Identities = 23/54 (42%), Positives = 35/54 (64%)
 Frame = +1

Query: 29 VVDIMRVNVDKVLERDQKLSELDDRADALQAGASQFETSAAKLKRKYWWKNCKM 82
          V+ IMR NV++V ER  +L +L D++D+L + A  F + +  L    WWKNC+M
Sbjct: 1  VMGIMRDNVNRVAERGDRLEDLQDKSDSLSSSADMFRSRSKSLHHNMWWKNCRM 162
>06063
          Length = 1216

 Score = 25.8 bits (55), Expect = 4.5,   Method: Compositional matrix adjust.
 Identities = 12/24 (50%), Positives = 17/24 (70%)
 Frame = -1

Query: 16  NRRLQQTQNQVDEVVDIMRVNVDK 39
           N+RLQQ+++ V  V D  R +VDK
Sbjct: 316 NKRLQQSRDPVIPVXDRHRPDVDK 245
>03298
          Length = 2006

 Score = 25.0 bits (53), Expect = 8.7,   Method: Composition-based stats.
 Identities = 12/31 (38%), Positives = 17/31 (54%)
 Frame = +1

Query: 6    PSGSSAATGSNRRLQQTQNQVDEVVDIMRVN 36
            P  SSAA G   R + T N  + +  +MRV+
Sbjct: 1450 PPKSSAANGPTNRNRTTMNHKENMKTVMRVD 1542
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|13507622|ref|NP_109617.1| SAC1 (supressor of actin
mutations 1, homolog)-like [Mus musculus]
         (587 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

36825                                                                  63   3e-10
36691                                                                  49   6e-06
30449                                                                  33   0.24 
18016                                                                  29   6.5  
28225                                                                  28   7.6  
>36825
          Length = 655

 Score = 62.8 bits (151), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 37/103 (35%), Positives = 57/103 (55%), Gaps = 2/103 (1%)
 Frame = -3

Query: 102 KTMLHLTDIQLQDNKTFLAMLNHVLSMDGFYFSTTYDLTHTLQRLSNTSPEFQEMSLLER 161
           K+   + D +  + + +  +L      D FYFS TYDLT++LQR  N +    +  L ER
Sbjct: 359 KSRKDVKDKEKFERRIYEELLKMYNDSDFFYFSDTYDLTNSLQR-QNMADYPTDKGLGER 183

Query: 162 ADQRFVWNGHLLREL-SAQPEV-HRFALPVLHGFITMHSCSIN 202
           AD+RF WN  +L EL   Q E+   + LP++ GF+ M  C ++
Sbjct: 182 ADERFFWNKPMLEELIEEQTELASHWILPIIQGFVQMEICCMD 54
>36691
          Length = 389

 Score = 48.9 bits (115), Expect = 6e-06,   Method: Composition-based stats.
 Identities = 27/86 (31%), Positives = 39/86 (45%), Gaps = 6/86 (6%)
 Frame = +2

Query: 386 RSNCMDCLDRTNVIXXXXXXXXXXXXXXXXGVLHVGQKLEEQDEFEKTYKNAWADNANAC 445
           R+NC+DCLDRTN +                G+     K +    FE+ Y+  W  + +  
Sbjct: 8   RTNCLDCLDRTNAVQTMIGMEVLPKQLECLGL---ASKAQMVGRFEEVYRQIWQHSGDHI 178

Query: 446 AKQYAGTGALK------TDFTRTGKR 465
           ++ YAGTGAL        D TR+  R
Sbjct: 179 SRIYAGTGALGGGRSKYQDATRSATR 256
>30449
          Length = 457

 Score = 33.5 bits (75), Expect = 0.24,   Method: Compositional matrix adjust.
 Identities = 14/45 (31%), Positives = 25/45 (55%)
 Frame = -3

Query: 54  TRPIFGILGTIHLVAGNYLVVITKKMKVGECFNHAVWRATDFDVL 98
           T   FGI G +  + G Y+++ITK+ +V     H +++  D  +L
Sbjct: 218 TTSAFGIAGFVRFLEGPYIILITKRKRVALIGPHTIYKIEDTSML 84
>18016
          Length = 1504

 Score = 28.9 bits (63), Expect = 6.5,   Method: Compositional matrix adjust.
 Identities = 17/59 (28%), Positives = 31/59 (52%), Gaps = 7/59 (11%)
 Frame = +3

Query: 115 NKTFLAMLNHVLSMDGFYFSTTYDLT-------HTLQRLSNTSPEFQEMSLLERADQRF 166
           N++FL M  H++++       +++LT       HT  +  N  P F +M +L + DQ+F
Sbjct: 99  NQSFLNMFTHLVNIPHTQ-PHSHNLTLPHLPHTHTHTQYKNIKPNFPDMLILHQVDQQF 272
>28225
          Length = 490

 Score = 28.5 bits (62), Expect = 7.6,   Method: Compositional matrix adjust.
 Identities = 13/27 (48%), Positives = 19/27 (70%)
 Frame = +1

Query: 111 QLQDNKTFLAMLNHVLSMDGFYFSTTY 137
           ++QD  T L   NH+LSMDG++F+  Y
Sbjct: 190 EIQD--TLLYGSNHILSMDGYHFAGNY 264
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|34147232|ref|NP_899002.1| potassium channel,
subfamily V, member 2 [Mus musculus]
         (562 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

33196                                                                  63   3e-10
26719                                                                  49   5e-06
31326                                                                  47   2e-05
06904                                                                  29   5.1  
>33196
          Length = 373

 Score = 62.8 bits (151), Expect = 3e-10,   Method: Composition-based stats.
 Identities = 36/116 (31%), Positives = 57/116 (49%)
 Frame = -3

Query: 107 LKVNVGGHSYLLECCELANYPKTRLGRLATSTTRRGQLGLCDDYEAQTDEYFFDRDPAVF 166
           LK+NV G  +      L  YP T LG                 Y+ ++ EYFFDRDP +F
Sbjct: 353 LKINVSGRKFETWRTTLEKYPDTLLGSNEKEFF----------YDEESKEYFFDRDPDLF 204

Query: 167 QLIYNFYTSGVLLVRDELCPRSFLEELGYWGVRLKYTPRCCRICFEERRDELSEQL 222
           + I N+Y +G L      C  ++ +EL ++G+  +    CC   + +R+ E +E+L
Sbjct: 203 RHILNYYRTGSLHYPKHECISAYDDELAFFGIMPEIIGDCCYEDYRDRKRENAERL 36
>26719
          Length = 394

 Score = 48.9 bits (115), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 32/90 (35%), Positives = 53/90 (58%), Gaps = 10/90 (11%)
 Frame = -3

Query: 422 RQCYQQVGCLMLFITMGIFS-FSAAVYSVEHDVPGTN--------FTSILH-AWWWAAVS 471
           R+C+Q++  L+L +  G+ + F A  + +EH   G+N        F S L  + +WA ++
Sbjct: 275 RRCHQEL-LLLLVVFAGLSTLFGALTFFLEHH-SGSNEKGHNSRPFASDLTGSVYWAIIT 102

Query: 472 ISTVGYGDMYPETHLGRLFAFLCIAFGIIL 501
           ++TVGYGD+ P T LGR+   LC   G+I+
Sbjct: 101 MTTVGYGDITPSTTLGRVMGVLCSLIGVIV 12
>31326
          Length = 383

 Score = 46.6 bits (109), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 19/49 (38%), Positives = 30/49 (61%)
 Frame = -2

Query: 159 FDRDPAVFQLIYNFYTSGVLLVRDELCPRSFLEELGYWGVRLKYTPRCC 207
           FDRDP VF+ I N++T+  L +  ++C  +   EL +WG++     RCC
Sbjct: 325 FDRDPDVFRAILNYFTTDELHLPIQVCGLAVKNELDFWGIKEHEIQRCC 179
>06904
          Length = 547

 Score = 28.9 bits (63), Expect = 5.1,   Method: Compositional matrix adjust.
 Identities = 12/48 (25%), Positives = 28/48 (58%)
 Frame = -2

Query: 462 LHAWWWAAVSISTVGYGDMYPETHLGRLFAFLCIAFGIILNGMPISIL 509
           L ++++  ++ ST+G+GD+ PE     L + +    G+ L  M ++++
Sbjct: 177 LESFYFVFITTSTIGFGDVLPEHPNFFLLSCVYTFLGLALVSMTVNVI 34
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|51768494|ref|XP_484387.1| PREDICTED: retinitis
pigmentosa 1 homolog (human)-like 1 isoform 1 [Mus musculus]
         (1859 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

14591                                                                  65   3e-10
02841                                                                  45   2e-04
26514                                                                  32   2.0  
>14591
          Length = 1324

 Score = 65.1 bits (157), Expect = 3e-10,   Method: Composition-based stats.
 Identities = 57/255 (22%), Positives = 103/255 (40%), Gaps = 65/255 (25%)
 Frame = +1

Query: 42  KKITFLKRGDPQFAGVRLAVHQRTFKTFSSLMDELSQRMP----LSFGVRSVTTPRGLHG 97
           +K+ F   GD  F G +L +    +  F+ L+++L+ ++P    L +GVR + TP G   
Sbjct: 61  RKVRFFVNGDRFFKGKKLHITPHRYYNFTDLLNDLTGKLPSSINLPYGVRQIFTPVGGRR 240

Query: 98  LSALEQLQDGGCYLCSDRKPPKTSREPGRLQRKSPSAGQA---QVFQGGHEAPETSYS-- 152
           +S +E LQDG  Y+C+  +  K  +  GR + +  S G++      Q    AP+ SY   
Sbjct: 241 VSDIEDLQDGETYVCAGFEGFKVIKY-GRTELEPWSVGKSGRLGPLQENEAAPDASYGSY 417

Query: 153 -------------------------------WKG-------------------PVAPRRL 162
                                          W G                   P+ P+ +
Sbjct: 418 KYRGYATNAFHPGRYYRSNAAQGNGVQPTRRWPGTFGNQRNTGGLLTAPGEAVPIKPKVI 597

Query: 163 TLVKNGD-PRRQQTVVLSHKNTRSLAAFLGKASELL-----RFPVKQVYTTRGKKVDSLQ 216
           T+++NG  PR    ++L+ ++ +S    +   SE          ++++YT RG+++  + 
Sbjct: 598 TIIRNGQRPRNNIKILLNRRSIQSYEQLMSDISEAFGPKWKSNRIQRLYTMRGREIKGVA 777

Query: 217 TLLDGPSVLVCAGNE 231
                    V  GNE
Sbjct: 778 DFFRDDDCFVALGNE 822
>02841
          Length = 1442

 Score = 45.4 bits (106), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 24/82 (29%), Positives = 42/82 (51%), Gaps = 6/82 (7%)
 Frame = +3

Query: 156 PVAPRRLTLVKNGD-PRRQQTVVLSHKNTRSLAAFLGKASELL-----RFPVKQVYTTRG 209
           P+ PR +T+V+NG  PR    ++L+ ++ +S    +   SE          V+++YTT G
Sbjct: 324 PLKPRVITIVRNGHRPRTNVKLLLNRRSIQSFEQLMADISEAFGPKWKNNRVQKLYTTHG 503

Query: 210 KKVDSLQTLLDGPSVLVCAGNE 231
           K+V+S+          +  GNE
Sbjct: 504 KEVNSVSDFFREDDCFIAMGNE 569
>26514
          Length = 1092

 Score = 32.3 bits (72), Expect = 2.0,   Method: Composition-based stats.
 Identities = 19/57 (33%), Positives = 28/57 (49%)
 Frame = +3

Query: 805 FSFSVLLDRCPEADDPRTYHDCCCLQAVPSSPLAAPSGQTQTSISEACLGGSSFCPT 861
           FSF +LL   P+ D    +H CCCL+      L   + +TQ +   +CL  S +  T
Sbjct: 699 FSFFLLL-LTPKIDSFGIFHGCCCLRQ-----LRCAAHKTQXATQXSCLTQSQYTYT 851
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|57528312|ref|NP_444500.1| regulating synaptic
membrane exocytosis 1 isoform 1 [Mus musculus]
         (1463 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

16549                                                                  65   3e-10
29179                                                                  57   6e-08
31935                                                                  53   1e-06
26525                                                                  42   0.002
30040                                                                  39   0.022
00813                                                                  35   0.28 
09427                                                                  32   2.4  
13155                                                                  31   3.5  
27911                                                                  30   9.7  
>16549
          Length = 607

 Score = 64.7 bits (156), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 36/91 (39%), Positives = 53/91 (58%), Gaps = 1/91 (1%)
 Frame = +2

Query: 614 NPYVKMYFLPDRSDKSKRRTKTVKKLLEPKWNQTFVYSHVHRRDFRERMLEITVWDQPRV 673
           +PYVK Y LPD   ++KR+TK VK  + P +N+   Y  +   + R R L++TVWD   +
Sbjct: 62  SPYVKTYLLPDPEKQTKRKTKIVKHSVHPTFNEVLQYR-MKETETRHRTLQVTVWDHDML 238

Query: 674 QDEESEFLGEILIEL-ETALLDDEPHWYKLQ 703
           +  E+ FLG + + L +  L DD   WY LQ
Sbjct: 239 K--ENNFLGAVYLRLRDLELSDDTAKWYTLQ 325

 Score = 57.0 bits (136), Expect = 5e-08,   Method: Compositional matrix adjust.
 Identities = 34/109 (31%), Positives = 56/109 (51%), Gaps = 3/109 (2%)
 Frame = +2

Query: 1324 LEVEVIRARSLTQKPGSKSTPAPYVKVYLLENGACIAKKKTRIARKTLDPLYQQSLVF-- 1381
            L + V+  R L +   S   P+PYVK YLL +     K+KT+I + ++ P + + L +  
Sbjct: 8    LHIMVMHVRDLAR---SAELPSPYVKTYLLPDPEKQTKRKTKIVKHSVHPTFNEVLQYRM 178

Query: 1382 -DESPQGKVLQVIVWGDYGRMDHKCFMGVAQILLEELDLSSMVIGWYKL 1429
             +   + + LQV VW D+  +    F+G   + L +L+LS     WY L
Sbjct: 179  KETETRHRTLQVTVW-DHDMLKENNFLGAVYLRLRDLELSDDTAKWYTL 322
>29179
          Length = 1113

 Score = 57.0 bits (136), Expect = 6e-08,   Method: Compositional matrix adjust.
 Identities = 44/151 (29%), Positives = 68/151 (45%), Gaps = 1/151 (0%)
 Frame = -3

Query: 554 MERPSISVISPTSPGALKDAPQVLPGQLSVKLWYDKVGHQLIVNVLQATDLPPRVDGRPR 613
           ME P   V+   + G + +      G++   L YD     L + +++A DLP +      
Sbjct: 607 MEDPE--VVEEHATGPIVEGVDYKLGRIQFGLMYDFQNLTLTLRIIRAVDLPAKDVTGTS 434

Query: 614 NPYVKMYFLPDRSDKSKRRTKTVKKLLEPKWNQTFVYSHVHRRDFRERMLEITVWDQPRV 673
           +PYVK+  LPD+  K K  TK  K+ L P WN+ F++         E+ L + V D  R 
Sbjct: 433 DPYVKILLLPDK--KHKLLTKVKKRNLNPHWNECFLFEGWPHNKLLEKTLYLQVIDYDRF 260

Query: 674 QDEESEFLGEILIELETALLDDEP-HWYKLQ 703
             ++   +GE  + L    L   P  W  LQ
Sbjct: 259 SRDDP--IGETYLPLNEIDLSQSPVSWKYLQ 173

 Score = 49.3 bits (116), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 37/127 (29%), Positives = 63/127 (49%), Gaps = 5/127 (3%)
 Frame = -3

Query: 1310 MGDIQIGM--EDKKGQLEVEVIRARSLTQKPGSKSTPAPYVKVYLLENGACIAKKKTRIA 1367
            +G IQ G+  + +   L + +IRA  L  K  +  T  PYVK+ LL +     K  T++ 
Sbjct: 541  LGRIQFGLMYDFQNLTLTLRIIRAVDLPAKDVT-GTSDPYVKILLLPDKK--HKLLTKVK 371

Query: 1368 RKTLDPLYQQSLVFDESPQGKVLQVIVWG---DYGRMDHKCFMGVAQILLEELDLSSMVI 1424
            ++ L+P + +  +F+  P  K+L+  ++    DY R      +G   + L E+DLS   +
Sbjct: 370  KRNLNPHWNECFLFEGWPHNKLLEKTLYLQVIDYDRFSRDDPIGETYLPLNEIDLSQSPV 191

Query: 1425 GWYKLFP 1431
             W  L P
Sbjct: 190  SWKYLQP 170
>31935
          Length = 554

 Score = 52.8 bits (125), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 32/111 (28%), Positives = 56/111 (50%)
 Frame = -3

Query: 579 GQLSVKLWYDKVGHQLIVNVLQATDLPPRVDGRPRNPYVKMYFLPDRSDKSKRRTKTVKK 638
           G++ + + Y     +L V + +  ++P R      +PYVK++ LP RS +SKR+T  +K 
Sbjct: 537 GRIQLTITYSAQRQKLDVTIHKIMNIPLRDPSSIPDPYVKLHLLPGRSKESKRKTSIIKD 358

Query: 639 LLEPKWNQTFVYSHVHRRDFRERMLEITVWDQPRVQDEESEFLGEILIELE 689
              P ++ +F Y  +   + R   LE+TV  Q       S  +G + I L+
Sbjct: 357 NCNPVYDASFEYL-ISISELRHTELEVTVCTQKGFLSSGSPIIGMLKIPLD 208

 Score = 32.7 bits (73), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 22/75 (29%), Positives = 41/75 (54%), Gaps = 2/75 (2%)
 Frame = -3

Query: 1309 AMGDIQ--IGMEDKKGQLEVEVIRARSLTQKPGSKSTPAPYVKVYLLENGACIAKKKTRI 1366
             +G IQ  I    ++ +L+V + +  ++  +  S S P PYVK++LL   +  +K+KT I
Sbjct: 543  GLGRIQLTITYSAQRQKLDVTIHKIMNIPLRDPS-SIPDPYVKLHLLPGRSKESKRKTSI 367

Query: 1367 ARKTLDPLYQQSLVF 1381
             +   +P+Y  S  +
Sbjct: 366  IKDNCNPVYDASFEY 322
>26525
          Length = 455

 Score = 42.0 bits (97), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 23/55 (41%), Positives = 36/55 (65%), Gaps = 3/55 (5%)
 Frame = +1

Query: 603 DLPPR---VDGRPRNPYVKMYFLPDRSDKSKRRTKTVKKLLEPKWNQTFVYSHVH 654
           DLPPR   + G   +PYVK+  LP++  K K +T+ V+K L PK+++TF +  V+
Sbjct: 1   DLPPRDPSLGGC--DPYVKLQLLPEK--KHKCKTRVVRKTLNPKYDETFTFFGVN 153

 Score = 33.1 bits (74), Expect = 0.79,   Method: Compositional matrix adjust.
 Identities = 17/36 (47%), Positives = 22/36 (61%)
 Frame = +1

Query: 1346 PYVKVYLLENGACIAKKKTRIARKTLDPLYQQSLVF 1381
            PYVK+ LL       K KTR+ RKTL+P Y ++  F
Sbjct: 40   PYVKLQLLPEKK--HKCKTRVVRKTLNPKYDETFTF 141
>30040
          Length = 652

 Score = 38.5 bits (88), Expect = 0.022,   Method: Composition-based stats.
 Identities = 18/60 (30%), Positives = 37/60 (61%)
 Frame = -3

Query: 1323 QLEVEVIRARSLTQKPGSKSTPAPYVKVYLLENGACIAKKKTRIARKTLDPLYQQSLVFD 1382
            +L V +++A+ L     S  +  P+V+V LL  G  + +KKT + R +++P++ ++L F+
Sbjct: 614  RLTVVLMKAKDLKMST-SHPSADPFVRVSLLVEGKKVKRKKTSVRRASINPVWNEALAFN 438

 Score = 33.5 bits (75), Expect = 0.62,   Method: Composition-based stats.
 Identities = 25/128 (19%), Positives = 55/128 (42%)
 Frame = -3

Query: 583 VKLWYDKVGHQLIVNVLQATDLPPRVDGRPRNPYVKMYFLPDRSDKSKRRTKTVKKLLEP 642
           + L Y     +L V +++A DL         +P+V++  L +     +++T   +  + P
Sbjct: 644 ISLSYLPAAERLTVVLMKAKDLKMSTSHPSADPFVRVSLLVEGKKVKRKKTSVRRASINP 465

Query: 643 KWNQTFVYSHVHRRDFRERMLEITVWDQPRVQDEESEFLGEILIELETALLDDEPHWYKL 702
            WN+   + +V      +  LE++V D   +     + LG  ++       D+  HW ++
Sbjct: 464 VWNEALAF-NVPAEVLPKVTLEVSVLDHDLIG--HGDVLGTCVLGAGCG-GDELGHWNEM 297

Query: 703 QTHDESSL 710
             H   ++
Sbjct: 296 MLHQRKTI 273
>00813
          Length = 2775

 Score = 34.7 bits (78), Expect = 0.28,   Method: Compositional matrix adjust.
 Identities = 20/69 (28%), Positives = 34/69 (49%), Gaps = 1/69 (1%)
 Frame = +1

Query: 128 YQGEHKDDAPTCGICHKTKFADGCGHL-CSYCRTKFCARCGGRVSLRSNNEDKVVMWVCN 186
           Y+GE ++ A   G  +K  +  GC HL C++  T   ++  GR  + S        W+ +
Sbjct: 916 YRGELREKAMEMGAVYKPDWGKGCTHLVCAFPNTPKYSQVKGRGKIVSKQ------WISD 1077

Query: 187 LCRKQQEIL 195
            C KQ++ L
Sbjct: 1078-CYKQKKXL 1101
>09427
          Length = 1006

 Score = 31.6 bits (70), Expect = 2.4,   Method: Composition-based stats.
 Identities = 24/77 (31%), Positives = 31/77 (40%)
 Frame = +1

Query: 108 HQQFESYKEQVRKIGEEARRYQGEHKDDAPTCGICHKTKFADGCGHLCSYCRTKFCARCG 167
           H Q+E +   +RKIGE  R       +   +   CH+  F     H     R  FC RC 
Sbjct: 352 H*QYEKHTIILRKIGEPIR---ARS*NCNSSVMKCHQLWF-----HFLFILRRAFCKRCP 507

Query: 168 GRVSLRSNNEDKVVMWV 184
              SL  N    V +WV
Sbjct: 508 HFESLVHNTPSHVNIWV 558
>13155
          Length = 663

 Score = 31.2 bits (69), Expect = 3.5,   Method: Compositional matrix adjust.
 Identities = 23/91 (25%), Positives = 38/91 (41%), Gaps = 23/91 (25%)
 Frame = -2

Query: 1362 KKTRIARKTLDPLYQQSLVFDESPQGKV---------------LQVIVWGD--------Y 1398
            ++T + +KT+ P + +   FD + +G+                L V  W D         
Sbjct: 296  RRTAVRKKTICPQFDEVFSFDLNNRGQNQDRNNYSFDDVYEGELSVSXWHDDSRVSREVL 117

Query: 1399 GRMDHKCFMGVAQILLEELDLSSMVIGWYKL 1429
            G M    F+G  +I L +LDL++    WY L
Sbjct: 116  GNMFPGSFLGEVKIALRDLDLATAHTAWYCL 24
>27911
          Length = 376

 Score = 29.6 bits (65), Expect = 9.7,   Method: Composition-based stats.
 Identities = 12/36 (33%), Positives = 16/36 (44%)
 Frame = -2

Query: 131 EHKDDAPTCGICHKTKFADGCGHLCSYCRTKFCARC 166
           +H+DD   C  C +        H C +C   FCA C
Sbjct: 138 QHEDDVEDCNNCRQAFSVTKRKHHCRHCGRIFCADC 31
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6680774|ref|NP_031563.1| BCL2-like 2 [Mus musculus]
         (193 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

37633                                                                  61   3e-10
12826                                                                  54   4e-08
08158                                                                  43   8e-07
04946                                                                  26   9.5  
>37633
          Length = 664

 Score = 60.8 bits (146), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 40/145 (27%), Positives = 67/145 (46%), Gaps = 4/145 (2%)
 Frame = +1

Query: 9   DTRALVADFVGYKLRQKGYVCXXXXXXXXXXXXLHQAMRAAGDEFETRFRRTFSDLAAQL 68
           +T+ L + ++ ++L  KG +             +   + AAG E E  + R ++D+  ++
Sbjct: 28  ETKLLCSHYIHHRLTSKG-LATRRAQVSPHRTTVADELVAAGQELERLYPRVYTDICRRI 204

Query: 69  HVT---PGSAQQRFTQVSDELFQG-GPNWGRLVAFFVFGAALCAESVNKEMEPLVGQVQD 124
            +T   P       T V +++F G G  WGR+VA     AA   E V +     V  V D
Sbjct: 205 SMTMTSPEVVHHALTFVLEDIFPGSGVTWGRVVAMVSIMAAFAEECVVQGHANFVEDVVD 384

Query: 125 WMVAYLETRLADWIHSSGGWAEFTA 149
            +  ++  RLA W+ + GGW  F A
Sbjct: 385 SVGHFVHHRLATWMVNIGGWTAFPA 459
>12826
          Length = 829

 Score = 53.9 bits (128), Expect = 4e-08,   Method: Compositional matrix adjust.
 Identities = 33/109 (30%), Positives = 52/109 (47%), Gaps = 3/109 (2%)
 Frame = +3

Query: 42  LHQAMRAAGDEFETRFRRTFSDLAAQLHVTPGSAQ---QRFTQVSDELFQGGPNWGRLVA 98
           L + +  A  E E  + R +SD++ ++ +T  SAQ   +  T V D  F+ G  WG++V+
Sbjct: 276 LAEEVCCAAQELERLYPRVYSDVSRRIAMTMSSAQLVRRALTTVLDGTFRAGVTWGKVVS 455

Query: 99  FFVFGAALCAESVNKEMEPLVGQVQDWMVAYLETRLADWIHSSGGWAEF 147
             V  AA   E V +     V  V   +  +    LA W+   GGW+ F
Sbjct: 456 MVVIAAAFAEECVVQGHPDFVEDVVMCVGHFTSLHLASWLALQGGWSAF 602
>08158
          Length = 1019

 Score = 43.1 bits (100), Expect(2) = 8e-07,   Method: Compositional matrix adjust.
 Identities = 22/71 (30%), Positives = 35/71 (49%), Gaps = 1/71 (1%)
 Frame = +2

Query: 44  QAMRAAGDEFETRFRRTFSDLAAQLHVTPGSAQQRFTQVSDELFQGGP-NWGRLVAFFVF 102
           + MR    E  +R    F  +  +L++   +  Q F  V+DE+F  G  NWGR+VA + F
Sbjct: 368 KTMRRTVKELSSRHDIAFKGMVNKLNMDSSNPFQTFVNVADEIFDDGQINWGRIVAVYAF 547

Query: 103 GAALCAESVNK 113
            + L     +K
Sbjct: 548 ASRLATRESDK 580

 Score = 25.8 bits (55), Expect(2) = 8e-07,   Method: Compositional matrix adjust.
 Identities = 12/31 (38%), Positives = 17/31 (54%), Gaps = 1/31 (3%)
 Frame = +1

Query: 129 YLETRLADWIHSSGGWAEFTALYGD-GALEE 158
           Y+  +L  WI  +GGW  F   + D G +EE
Sbjct: 619 YVANKLGKWILDNGGWEAFADYFPDHGEIEE 711
>04946
          Length = 2841

 Score = 26.2 bits (56), Expect = 9.5,   Method: Compositional matrix adjust.
 Identities = 10/26 (38%), Positives = 13/26 (50%)
 Frame = +3

Query: 139  HSSGGWAEFTALYGDGALEEARRLRE 164
            H + GW      + DG+L E RR R 
Sbjct: 2202 HRNRGWGSLVTTFKDGSLSELRRWRN 2279
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|124053457|ref|NP_034950.2| multiple PDZ domain
protein [Mus musculus]
         (2055 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

37239                                                                  65   4e-10
20073                                                                  62   3e-09
26154                                                                  60   8e-09
27345                                                                  58   3e-08
03831                                                                  58   4e-08
29705                                                                  57   9e-08
01502                                                                  46   2e-04
02951                                                                  45   2e-04
08480                                                                  44   5e-04
03499                                                                  44   7e-04
38751                                                                  40   0.007
39267                                                                  36   0.14 
>37239
          Length = 453

 Score = 64.7 bits (156), Expect = 4e-10,   Method: Compositional matrix adjust.
 Identities = 31/64 (48%), Positives = 45/64 (70%), Gaps = 2/64 (3%)
 Frame = -2

Query: 1370 PTGAAGRDGRLQIADELLEINGQILYGRSHQNASSIIK--CAPSKVKIIFIRNADAVNQM 1427
            P   A RD R+ + DELLEING +L+GR H NAS+I+K   AP  VK++  R AD+++++
Sbjct: 449  PDSPAARDARIHVGDELLEINGNLLHGRCHLNASAIVKSVTAPD-VKLVVNRRADSLDRI 273

Query: 1428 AVCP 1431
            A+ P
Sbjct: 272  AIKP 261

 Score = 41.2 bits (95), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 42/133 (31%), Positives = 64/133 (48%), Gaps = 3/133 (2%)
 Frame = -2

Query: 576 PEGPVGHSGKLFSGDELLEVNGINLLGENHQDVVNILKELPI-DVTMVCCRRTVPPIALS 634
           P+ P     ++  GDELLE+NG  L G  H +   I+K +   DV +V  RR        
Sbjct: 449 PDSPAARDARIHVGDELLEINGNLLHGRCHLNASAIVKSVTAPDVKLVVNRRA------- 291

Query: 635 EMDSLDINDLELTEKPHIDLGEFIGSS-ETEDPMLAMSDVDQNAEEIQTPLAMWEAGGQS 693
             DSLD     +  KP + +G  IGS  E   P       D++++++ +  +  +   Q 
Sbjct: 290 --DSLD----RIAIKP-LRMGPSIGSEGEASKP-----SSDKDSKQVTSRPSTSDL-IQV 150

Query: 694 IELEK-GSRGLGF 705
           I L K G++GLGF
Sbjct: 149 ITLHKQGTQGLGF 111

 Score = 33.5 bits (75), Expect = 0.82,   Method: Compositional matrix adjust.
 Identities = 19/45 (42%), Positives = 26/45 (57%), Gaps = 1/45 (2%)
 Frame = -2

Query: 2010 AAEDGRLKRGDQIIAVNGQSLEGVTHEEAVAILKR-TKGTVTLMV 2053
            AA D R+  GD+++ +NG  L G  H  A AI+K  T   V L+V
Sbjct: 437  AARDARIHVGDELLEINGNLLHGRCHLNASAIVKSVTAPDVKLVV 303

 Score = 30.8 bits (68), Expect = 6.5,   Method: Composition-based stats.
 Identities = 15/28 (53%), Positives = 21/28 (75%), Gaps = 1/28 (3%)
 Frame = -3

Query: 1014 KDGL-GVIVRSIIHGGAISRDGRIAVGD 1040
            KDG  G+ +R I  GGA ++DG++AVGD
Sbjct: 91   KDGRHGIYIRHITIGGAAAKDGQLAVGD 8
>20073
          Length = 582

 Score = 61.6 bits (148), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 33/73 (45%), Positives = 47/73 (64%)
 Frame = +3

Query: 1981 GLGFSIVGGYGSPHGDLPIYVKTVFAKGAAAEDGRLKRGDQIIAVNGQSLEGVTHEEAVA 2040
            GLGF+++GG        PIY+  +   G A     LKRGDQ+++VNG S+EG  HE+AV 
Sbjct: 3    GLGFNVMGG---KEQSSPIYISRIIPGGVADRLNCLKRGDQLLSVNGVSVEGEYHEKAVE 173

Query: 2041 ILKRTKGTVTLMV 2053
            +LK  +G+V L+V
Sbjct: 174  LLKLAQGSVRLVV 212

 Score = 48.5 bits (114), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 28/70 (40%), Positives = 41/70 (58%), Gaps = 1/70 (1%)
 Frame = +3

Query: 1720 GLGLSIVG-KRNDTGVFVSDIVKGGIADADGRLMQGDQILMVNGEDVRHATQEAVAALLK 1778
            GLG +++G K   + +++S I+ GG+AD    L +GDQ+L VNG  V     E    LLK
Sbjct: 3    GLGFNVMGGKEQSSPIYISRIIPGGVADRLNCLKRGDQLLSVNGVSVEGEYHEKAVELLK 182

Query: 1779 CSLGAVTLEV 1788
             + G+V L V
Sbjct: 183  LAQGSVRLVV 212

 Score = 47.0 bits (110), Expect = 7e-05,   Method: Compositional matrix adjust.
 Identities = 25/69 (36%), Positives = 41/69 (59%)
 Frame = +3

Query: 1858 LGLSIAGGVGSPLGDVPIFIAMMHPNGVAAQTQKLRVGDRIVTICGTSTDGMTHTQAVNL 1917
            LG ++ GG        PI+I+ + P GVA +   L+ GD+++++ G S +G  H +AV L
Sbjct: 6    LGFNVMGGKEQ---SSPIYISRIIPGGVADRLNCLKRGDQLLSVNGVSVEGEYHEKAVEL 176

Query: 1918 MKNASGSIE 1926
            +K A GS+ 
Sbjct: 177  LKLAQGSVR 203

 Score = 45.1 bits (105), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 32/85 (37%), Positives = 50/85 (58%)
 Frame = +3

Query: 702 GLGFSILDYQDPIDPANTVIVIRSLVPGGIAEKDGRLFPGDRLMFVNDINLENSTLEEAV 761
           GLGF+++  ++   P    I I  ++PGG+A++   L  GD+L+ VN +++E    E+AV
Sbjct: 3   GLGFNVMGGKEQSSP----IYISRIIPGGVADRLNCLKRGDQLLSVNGVSVEGEYHEKAV 170

Query: 762 EALKGAPSGMVRIGVAKPLPLSPEE 786
           E LK A  G VR+ V +  P   EE
Sbjct: 171 ELLKLA-QGSVRL-VVRYTPQILEE 239

 Score = 43.5 bits (101), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 26/74 (35%), Positives = 47/74 (63%)
 Frame = +3

Query: 148 GLGFSVVGLRSENRGELGIFVQEIQEGSVAHRDGRLKETDQILAINGQVLDQTITHQQAI 207
           GLGF+V+G + ++     I++  I  G VA R   LK  DQ+L++NG  ++    H++A+
Sbjct: 3   GLGFNVMGGKEQSSP---IYISRIIPGGVADRLNCLKRGDQLLSVNGVSVEGE-YHEKAV 170

Query: 208 SILQKAKDTVQLVI 221
            +L+ A+ +V+LV+
Sbjct: 171 ELLKLAQGSVRLVV 212

 Score = 38.9 bits (89), Expect = 0.022,   Method: Compositional matrix adjust.
 Identities = 23/71 (32%), Positives = 38/71 (53%)
 Frame = +3

Query: 1623 GLGLSIVGGSDTLLGAIIIHEVYEEGAACKDGRLWAGDQILEVNGIDLRKATHDEAINVL 1682
            GLG +++GG +     I I  +   G A +   L  GDQ+L VNG+ +    H++A+ +L
Sbjct: 3    GLGFNVMGGKEQS-SPIYISRIIPGGVADRLNCLKRGDQLLSVNGVSVEGEYHEKAVELL 179

Query: 1683 RQTPQRVRLTL 1693
            +     VRL +
Sbjct: 180  KLAQGSVRLVV 212

 Score = 38.1 bits (87), Expect = 0.034,   Method: Compositional matrix adjust.
 Identities = 25/69 (36%), Positives = 37/69 (53%)
 Frame = +3

Query: 570 FIRSVLPEGPVGHSGKLFSGDELLEVNGINLLGENHQDVVNILKELPIDVTMVCCRRTVP 629
           +I  ++P G       L  GD+LL VNG+++ GE H+  V +LK     V +V   R  P
Sbjct: 51  YISRIIPGGVADRLNCLKRGDQLLSVNGVSVEGEYHEKAVELLKLAQGSVRLVV--RYTP 224

Query: 630 PIALSEMDS 638
            I L EM++
Sbjct: 225 QI-LEEMEA 248

 Score = 36.6 bits (83), Expect = 0.11,   Method: Compositional matrix adjust.
 Identities = 21/74 (28%), Positives = 42/74 (56%)
 Frame = +3

Query: 387 GLGITIAGYIGDKKLEPSGIFVKSITKSSAVEHDGRIQIGDQIIAVDGTNLQGFTNQQAV 446
           GLG  + G     K + S I++  I      +    ++ GDQ+++V+G +++G  +++AV
Sbjct: 3   GLGFNVMG----GKEQSSPIYISRIIPGGVADRLNCLKRGDQLLSVNGVSVEGEYHEKAV 170

Query: 447 EVLRHTGQTVRLTL 460
           E+L+    +VRL +
Sbjct: 171 ELLKLAQGSVRLVV 212

 Score = 35.8 bits (81), Expect = 0.19,   Method: Compositional matrix adjust.
 Identities = 22/79 (27%), Positives = 41/79 (51%)
 Frame = +3

Query: 1150 LGISIVGGRGMGSRLSNGEVMRGIFIKHVLEDSPAGKNGTLKPGDRIIEVDGMDLRDASH 1209
            LG +++GG+   S          I+I  ++    A +   LK GD+++ V+G+ +    H
Sbjct: 6    LGFNVMGGKEQSSP---------IYISRIIPGGVADRLNCLKRGDQLLSVNGVSVEGEYH 158

Query: 1210 EQAVEAIRKAGNPVVFMVQ 1228
            E+AVE ++ A   V  +V+
Sbjct: 159  EKAVELLKLAQGSVRLVVR 215

 Score = 34.3 bits (77), Expect = 0.55,   Method: Compositional matrix adjust.
 Identities = 16/55 (29%), Positives = 30/55 (54%)
 Frame = +3

Query: 280 VIVKTILPGGVADQHGRLCSGDHILKIGDTDLAGMSSEQVAQVLRQCGNRVKLMI 334
           + +  I+PGGVAD+   L  GD +L +    + G   E+  ++L+     V+L++
Sbjct: 48  IYISRIIPGGVADRLNCLKRGDQLLSVNGVSVEGEYHEKAVELLKLAQGSVRLVV 212
>26154
          Length = 446

 Score = 60.1 bits (144), Expect = 8e-09,   Method: Compositional matrix adjust.
 Identities = 38/121 (31%), Positives = 69/121 (57%), Gaps = 1/121 (0%)
 Frame = -3

Query: 1642 HEVYEEGAACKDGRLWAGDQILEVNGIDLRKATHDEAINVLRQTPQRVRLTLYRDEAPYK 1701
            H   + G+A + G + AGD+++ +N + L   T D+A ++L    + V+L + RD+    
Sbjct: 426  HGC*KRGSAHRCGSIQAGDKLMAINDVRLDTCTVDDATHLLELPDELVKLKVQRDDPDEG 247

Query: 1702 EEDVCDTFTIELQKRPGKGLGLSIVGKRND-TGVFVSDIVKGGIADADGRLMQGDQILMV 1760
             ED C T+T++L  R G  LG++I G  +    + +S++  GG+A   G +  GD++L +
Sbjct: 246  NED-CVTYTVQLY-RHGGPLGITISGTEDPLDNIVISELTAGGLAQKTGAMHVGDRLLGI 73

Query: 1761 N 1761
            N
Sbjct: 72   N 70

 Score = 39.3 bits (90), Expect = 0.019,   Method: Compositional matrix adjust.
 Identities = 21/57 (36%), Positives = 34/57 (59%)
 Frame = -3

Query: 693 SIELEKGSRGLGFSILDYQDPIDPANTVIVIRSLVPGGIAEKDGRLFPGDRLMFVND 749
           +++L +    LG +I   +DP+D     IVI  L  GG+A+K G +  GDRL+ +N+
Sbjct: 225 TVQLYRHGGPLGITISGTEDPLDN----IVISELTAGGLAQKTGAMHVGDRLLGINE 67

 Score = 36.6 bits (83), Expect = 0.10,   Method: Compositional matrix adjust.
 Identities = 19/63 (30%), Positives = 35/63 (55%), Gaps = 1/63 (1%)
 Frame = -3

Query: 989  SQEAFERTVTIAKGSSSLGMTVSANKDGL-GVIVRSIIHGGAISRDGRIAVGDCILSINE 1047
            +++    TV + +    LG+T+S  +D L  +++  +  GG   + G + VGD +L INE
Sbjct: 246  NEDCVTYTVQLYRHGGPLGITISGTEDPLDNIVISELTAGGLAQKTGAMHVGDRLLGINE 67

Query: 1048 EST 1050
             +T
Sbjct: 66   STT 58

 Score = 35.4 bits (80), Expect = 0.25,   Method: Compositional matrix adjust.
 Identities = 19/58 (32%), Positives = 34/58 (58%)
 Frame = -3

Query: 730 GIAEKDGRLFPGDRLMFVNDINLENSTLEEAVEALKGAPSGMVRIGVAKPLPLSPEEG 787
           G A + G +  GD+LM +ND+ L+  T+++A   L+  P  +V++ V +     P+EG
Sbjct: 408 GSAHRCGSIQAGDKLMAINDVRLDTCTVDDATHLLE-LPDELVKLKVQRD---DPDEG 247
>27345
          Length = 496

 Score = 58.2 bits (139), Expect = 3e-08,   Method: Composition-based stats.
 Identities = 37/104 (35%), Positives = 52/104 (50%), Gaps = 16/104 (15%)
 Frame = +3

Query: 405 GIFVKSITKSSAVEHDGRIQIGDQIIAVDGTNLQGFTNQQAVEVLRHTGQTVRLTLMRKG 464
           GIF+K++T   A + DGRIQ+ DQII VDG +L G T   A  VLR+T   V   + R  
Sbjct: 24  GIFIKTLTDGGAAQKDGRIQVNDQIIEVDGKSLVGVTQAYAASVLRNTSGQVTFHIGRDK 203

Query: 465 ASQEAELT----------SRGDTAKDVD------LPAENCEKDE 492
              ++E+            + DT +D +      L  + C KDE
Sbjct: 204 DPAKSEVARLIQQSLAQDRQRDTVRDREQDRMKQLEDQFCPKDE 335

 Score = 57.4 bits (137), Expect = 6e-08,   Method: Composition-based stats.
 Identities = 29/63 (46%), Positives = 41/63 (65%)
 Frame = +3

Query: 1991 GSPHGDLPIYVKTVFAKGAAAEDGRLKRGDQIIAVNGQSLEGVTHEEAVAILKRTKGTVT 2050
            G   G L I++KT+   GAA +DGR++  DQII V+G+SL GVT   A ++L+ T G VT
Sbjct: 3    GCRPGKLGIFIKTLTDGGAAQKDGRIQVNDQIIEVDGKSLVGVTQAYAASVLRNTSGQVT 182

Query: 2051 LMV 2053
              +
Sbjct: 183  FHI 191

 Score = 49.3 bits (116), Expect = 2e-05,   Method: Composition-based stats.
 Identities = 28/66 (42%), Positives = 37/66 (56%)
 Frame = +3

Query: 1638 AIIIHEVYEEGAACKDGRLWAGDQILEVNGIDLRKATHDEAINVLRQTPQRVRLTLYRDE 1697
             I I  + + GAA KDGR+   DQI+EV+G  L   T   A +VLR T  +V   + RD+
Sbjct: 24   GIFIKTLTDGGAAQKDGRIQVNDQIIEVDGKSLVGVTQAYAASVLRNTSGQVTFHIGRDK 203

Query: 1698 APYKEE 1703
             P K E
Sbjct: 204  DPAKSE 221

 Score = 48.9 bits (115), Expect = 2e-05,   Method: Composition-based stats.
 Identities = 23/60 (38%), Positives = 36/60 (60%)
 Frame = +3

Query: 1733 GVFVSDIVKGGIADADGRLMQGDQILMVNGEDVRHATQEAVAALLKCSLGAVTLEVGRVK 1792
            G+F+  +  GG A  DGR+   DQI+ V+G+ +   TQ   A++L+ + G VT  +GR K
Sbjct: 24   GIFIKTLTDGGAAQKDGRIQVNDQIIEVDGKSLVGVTQAYAASVLRNTSGQVTFHIGRDK 203

 Score = 45.1 bits (105), Expect = 3e-04,   Method: Composition-based stats.
 Identities = 22/62 (35%), Positives = 37/62 (59%)
 Frame = +3

Query: 162 GELGIFVQEIQEGSVAHRDGRLKETDQILAINGQVLDQTITHQQAISILQKAKDTVQLVI 221
           G+LGIF++ + +G  A +DGR++  DQI+ ++G+ L   +T   A S+L+     V   I
Sbjct: 15  GKLGIFIKTLTDGGAAQKDGRIQVNDQIIEVDGKSL-VGVTQAYAASVLRNTSGQVTFHI 191

Query: 222 AR 223
            R
Sbjct: 192 GR 197

 Score = 43.9 bits (102), Expect = 6e-04,   Method: Composition-based stats.
 Identities = 19/63 (30%), Positives = 39/63 (61%)
 Frame = +3

Query: 1360 RMSVFIVGIDPTGAAGRDGRLQIADELLEINGQILYGRSHQNASSIIKCAPSKVKIIFIR 1419
            ++ +FI  +   GAA +DGR+Q+ D+++E++G+ L G +   A+S+++    +V     R
Sbjct: 18   KLGIFIKTLTDGGAAQKDGRIQVNDQIIEVDGKSLVGVTQAYAASVLRNTSGQVTFHIGR 197

Query: 1420 NAD 1422
            + D
Sbjct: 198  DKD 206

 Score = 43.5 bits (101), Expect = 0.001,   Method: Composition-based stats.
 Identities = 19/50 (38%), Positives = 33/50 (66%)
 Frame = +3

Query: 1017 LGVIVRSIIHGGAISRDGRIAVGDCILSINEESTISLTNAQARAMLRRHS 1066
            LG+ ++++  GGA  +DGRI V D I+ ++ +S + +T A A ++LR  S
Sbjct: 21   LGIFIKTLTDGGAAQKDGRIQVNDQIIEVDGKSLVGVTQAYAASVLRNTS 170

 Score = 39.3 bits (90), Expect = 0.018,   Method: Composition-based stats.
 Identities = 20/56 (35%), Positives = 29/56 (51%)
 Frame = +3

Query: 1172 GIFIKHVLEDSPAGKNGTLKPGDRIIEVDGMDLRDASHEQAVEAIRKAGNPVVFMV 1227
            GIFIK + +   A K+G ++  D+IIEVDG  L   +   A   +R     V F +
Sbjct: 24   GIFIKTLTDGGAAQKDGRIQVNDQIIEVDGKSLVGVTQAYAASVLRNTSGQVTFHI 191

 Score = 38.5 bits (88), Expect = 0.029,   Method: Composition-based stats.
 Identities = 18/57 (31%), Positives = 29/57 (50%)
 Frame = +3

Query: 280 VIVKTILPGGVADQHGRLCSGDHILKIGDTDLAGMSSEQVAQVLRQCGNRVKLMIAR 336
           + +KT+  GG A + GR+   D I+++    L G++    A VLR    +V   I R
Sbjct: 27  IFIKTLTDGGAAQKDGRIQVNDQIIEVDGKSLVGVTQAYAASVLRNTSGQVTFHIGR 197

 Score = 32.0 bits (71), Expect = 2.9,   Method: Composition-based stats.
 Identities = 20/63 (31%), Positives = 32/63 (50%)
 Frame = +3

Query: 716 PANTVIVIRSLVPGGIAEKDGRLFPGDRLMFVNDINLENSTLEEAVEALKGAPSGMVRIG 775
           P    I I++L  GG A+KDGR+   D+++ V+  +L   T   A   L+   SG V   
Sbjct: 12  PGKLGIFIKTLTDGGAAQKDGRIQVNDQIIEVDGKSLVGVTQAYAASVLRNT-SGQVTFH 188

Query: 776 VAK 778
           + +
Sbjct: 189 IGR 197
>03831
          Length = 1143

 Score = 57.8 bits (138), Expect = 4e-08,   Method: Compositional matrix adjust.
 Identities = 56/228 (24%), Positives = 99/228 (43%), Gaps = 5/228 (2%)
 Frame = +3

Query: 404 SGIFVKSITKSSAVEHDGRIQIGDQIIAVDGTNLQGFTNQQAVEVLRHTGQTVRLTLMRK 463
           +G F+  + + S  E  G ++ GD+I+ V+GTN+    +QQ V  ++  G   RL ++ +
Sbjct: 204 AGQFIGKVDEGSPAEAAG-LKAGDRIVEVNGTNIGNENHQQVVGRIKAGGDETRLLVVDQ 380

Query: 464 GASQ---EAELTSRGDTAKDVDLPAENCEKDEESLSLKRNTSILPIEEEGFPLLSAELEE 520
              Q   E +   RGD  +   + A   +KD          +++       P       E
Sbjct: 381 ETDQHYKEEKRVVRGDLPETRFMTAAREQKDNXENQEAEIAAVVEATNGTEP-------E 539

Query: 521 AEDVQQEAALLTKWQRIMGINYEIVVAHVSKFSENSGLGISLEATVGH--HFIRSVLPEG 578
            + +  E++L           Y   + H+ K+++  G G +L A       +I SV P  
Sbjct: 540 PQSLPDESSL-----------YAPRLCHLCKWADFDGYGFNLHAEKDKPGQYIGSVDPNS 686

Query: 579 PVGHSGKLFSGDELLEVNGINLLGENHQDVVNILKELPIDVTMVCCRR 626
           P   +G L  GD ++EVNG N+   NH  V+  +K      +M+   +
Sbjct: 687 PA-ETGGLKEGDRIIEVNGENIETTNHTAVIQNIKSRGDKTSMLVVDK 827

 Score = 46.6 bits (109), Expect = 9e-05,   Method: Compositional matrix adjust.
 Identities = 27/70 (38%), Positives = 40/70 (57%), Gaps = 2/70 (2%)
 Frame = +3

Query: 546 VAHVSKFSENSGLGISLEATVGH--HFIRSVLPEGPVGHSGKLFSGDELLEVNGINLLGE 603
           + H+ ++S+ +G G +L A  G    FI  V  EG    +  L +GD ++EVNG N+  E
Sbjct: 135 LCHIVRWSDFNGYGFNLHAEKGKAGQFIGKV-DEGSPAEAAGLKAGDRIVEVNGTNIGNE 311

Query: 604 NHQDVVNILK 613
           NHQ VV  +K
Sbjct: 312 NHQQVVGRIK 341

 Score = 43.9 bits (102), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 27/69 (39%), Positives = 38/69 (55%)
 Frame = +3

Query: 1159 GMGSRLSNGEVMRGIFIKHVLEDSPAGKNGTLKPGDRIIEVDGMDLRDASHEQAVEAIRK 1218
            G G  L   +   G FI  V E SPA   G LK GDRI+EV+G ++ + +H+Q V  I+ 
Sbjct: 168  GYGFNLHAEKGKAGQFIGKVDEGSPAEAAG-LKAGDRIVEVNGTNIGNENHQQVVGRIKA 344

Query: 1219 AGNPVVFMV 1227
             G+    +V
Sbjct: 345  GGDETRLLV 371

 Score = 39.7 bits (91), Expect = 0.013,   Method: Compositional matrix adjust.
 Identities = 24/69 (34%), Positives = 37/69 (53%)
 Frame = +3

Query: 1159 GMGSRLSNGEVMRGIFIKHVLEDSPAGKNGTLKPGDRIIEVDGMDLRDASHEQAVEAIRK 1218
            G G  L   +   G +I  V  +SPA + G LK GDRIIEV+G ++   +H   ++ I+ 
Sbjct: 615  GYGFNLHAEKDKPGQYIGSVDPNSPA-ETGGLKEGDRIIEVNGENIETTNHTAVIQNIKS 791

Query: 1219 AGNPVVFMV 1227
             G+    +V
Sbjct: 792  RGDKTSMLV 818

 Score = 36.6 bits (83), Expect = 0.10,   Method: Compositional matrix adjust.
 Identities = 23/75 (30%), Positives = 38/75 (50%)
 Frame = +3

Query: 1980 DGLGFSIVGGYGSPHGDLPIYVKTVFAKGAAAEDGRLKRGDQIIAVNGQSLEGVTHEEAV 2039
            DG GF++      P      Y+ +V    + AE G LK GD+II VNG+++E   H   +
Sbjct: 612  DGYGFNLHAEKDKPGQ----YIGSV-DPNSPAETGGLKEGDRIIEVNGENIETTNHTAVI 776

Query: 2040 AILKRTKGTVTLMVL 2054
              +K      +++V+
Sbjct: 777  QNIKSRGDKTSMLVV 821

 Score = 33.1 bits (74), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 17/60 (28%), Positives = 32/60 (53%)
 Frame = +3

Query: 1720 GLGLSIVGKRNDTGVFVSDIVKGGIADADGRLMQGDQILMVNGEDVRHATQEAVAALLKC 1779
            G G ++  ++   G F+  + +G  A+A G L  GD+I+ VNG ++ +   + V   +K 
Sbjct: 168  GYGFNLHAEKGKAGQFIGKVDEGSPAEAAG-LKAGDRIVEVNGTNIGNENHQQVVGRIKA 344

 Score = 33.1 bits (74), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 19/60 (31%), Positives = 31/60 (51%), Gaps = 2/60 (3%)
 Frame = +3

Query: 1646 EEGAACKDGRLWAGDQILEVNGIDLRKATHDEAINVLRQTPQRVRLTLYRDEAP--YKEE 1703
            +EG+  +   L AGD+I+EVNG ++    H + +  ++      RL +   E    YKEE
Sbjct: 228  DEGSPAEAAGLKAGDRIVEVNGTNIGNENHQQVVGRIKAGGDETRLLVVDQETDQHYKEE 407

 Score = 31.6 bits (70), Expect = 3.3,   Method: Compositional matrix adjust.
 Identities = 16/48 (33%), Positives = 27/48 (56%)
 Frame = +3

Query: 2007 KGAAAEDGRLKRGDQIIAVNGQSLEGVTHEEAVAILKRTKGTVTLMVL 2054
            +G+ AE   LK GD+I+ VNG ++    H++ V  +K       L+V+
Sbjct: 231  EGSPAEAAGLKAGDRIVEVNGTNIGNENHQQVVGRIKAGGDETRLLVV 374
>29705
          Length = 674

 Score = 57.0 bits (136), Expect = 9e-08,   Method: Compositional matrix adjust.
 Identities = 33/75 (44%), Positives = 44/75 (58%), Gaps = 2/75 (2%)
 Frame = -1

Query: 1981 GLGFSIVGGYGSPH--GDLPIYVKTVFAKGAAAEDGRLKRGDQIIAVNGQSLEGVTHEEA 2038
            G G     G G+ H  GD  I++  V   G+A +DGR+   D+++AVN  +LE VTHEEA
Sbjct: 419  GSGIQHCRGKGNQHIPGDNGIFITKVIEGGSAEQDGRIAVMDRLLAVNEHNLEDVTHEEA 240

Query: 2039 VAILKRTKGTVTLMV 2053
            VA LK T   V L +
Sbjct: 239  VAALKSTGDVVRLTI 195

 Score = 56.2 bits (134), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 35/89 (39%), Positives = 52/89 (58%)
 Frame = -1

Query: 716 PANTVIVIRSLVPGGIAEKDGRLFPGDRLMFVNDINLENSTLEEAVEALKGAPSGMVRIG 775
           P +  I I  ++ GG AE+DGR+   DRL+ VN+ NLE+ T EEAV ALK     +VR+ 
Sbjct: 374 PGDNGIFITKVIEGGSAEQDGRIAVMDRLLAVNEHNLEDVTHEEAVAALKST-GDVVRLT 198

Query: 776 VAKPLPLSPEEGYVSAKEDAFLCSPHACK 804
           +AKP  ++     +S+ +D     PH  +
Sbjct: 197 IAKPTYIAD----LSSHDDDPESGPHHSQ 123

 Score = 55.1 bits (131), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 36/91 (39%), Positives = 51/91 (56%)
 Frame = -2

Query: 1645 YEEGAACKDGRLWAGDQILEVNGIDLRKATHDEAINVLRQTPQRVRLTLYRDEAPYKEED 1704
            Y  GAA +DGRL   D I++V   D+   TH  A++ L+++  RV L + R + P   E 
Sbjct: 628  YRGGAAAEDGRLRLNDIIVKVGTEDVSNTTHTAAVDALKRSGNRVYLQVKRLKIP--TEK 455

Query: 1705 VCDTFTIELQKRPGKGLGLSIVGKRNDTGVF 1735
            V D   I+L K   KGLG SI G++ +T  F
Sbjct: 454  VID---IDLVKGVNKGLGFSIAGEK-ETSTF 374

 Score = 54.3 bits (129), Expect = 4e-07,   Method: Compositional matrix adjust.
 Identities = 32/92 (34%), Positives = 55/92 (59%), Gaps = 1/92 (1%)
 Frame = -1

Query: 386 QGLGITIAGYIGDKKLE-PSGIFVKSITKSSAVEHDGRIQIGDQIIAVDGTNLQGFTNQQ 444
           QG GI      G++ +   +GIF+  + +  + E DGRI + D+++AV+  NL+  T+++
Sbjct: 422 QGSGIQHCRGKGNQHIPGDNGIFITKVIEGGSAEQDGRIAVMDRLLAVNEHNLEDVTHEE 243

Query: 445 AVEVLRHTGQTVRLTLMRKGASQEAELTSRGD 476
           AV  L+ TG  VRLT+ +   +  A+L+S  D
Sbjct: 242 AVAALKSTGDVVRLTIAK--PTYIADLSSHDD 153

 Score = 52.0 bits (123), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 24/62 (38%), Positives = 42/62 (67%)
 Frame = -1

Query: 162 GELGIFVQEIQEGSVAHRDGRLKETDQILAINGQVLDQTITHQQAISILQKAKDTVQLVI 221
           G+ GIF+ ++ EG  A +DGR+   D++LA+N   L + +TH++A++ L+   D V+L I
Sbjct: 371 GDNGIFITKVIEGGSAEQDGRIAVMDRLLAVNEHNL-EDVTHEEAVAALKSTGDVVRLTI 195

Query: 222 AR 223
           A+
Sbjct: 194 AK 189

 Score = 47.0 bits (110), Expect = 9e-05,   Method: Compositional matrix adjust.
 Identities = 24/57 (42%), Positives = 36/57 (63%)
 Frame = -1

Query: 1639 IIIHEVYEEGAACKDGRLWAGDQILEVNGIDLRKATHDEAINVLRQTPQRVRLTLYR 1695
            I I +V E G+A +DGR+   D++L VN  +L   TH+EA+  L+ T   VRLT+ +
Sbjct: 359  IFITKVIEGGSAEQDGRIAVMDRLLAVNEHNLEDVTHEEAVAALKSTGDVVRLTIAK 189

 Score = 45.4 bits (106), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 32/106 (30%), Positives = 52/106 (49%), Gaps = 10/106 (9%)
 Frame = -1

Query: 1695 RDEAPYKEEDVCDTFTIELQKRPGKG--LGLSI---VGKRN-----DTGVFVSDIVKGGI 1744
            R ++    E   D+     + RPG+G   G  I    GK N     D G+F++ +++GG 
Sbjct: 506  RQQSLLASETAEDSDRKSHRHRPGQGS*QGSGIQHCRGKGNQHIPGDNGIFITKVIEGGS 327

Query: 1745 ADADGRLMQGDQILMVNGEDVRHATQEAVAALLKCSLGAVTLEVGR 1790
            A+ DGR+   D++L VN  ++   T E   A LK +   V L + +
Sbjct: 326  AEQDGRIAVMDRLLAVNEHNLEDVTHEEAVAALKSTGDVVRLTIAK 189

 Score = 43.1 bits (100), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 24/70 (34%), Positives = 41/70 (58%)
 Frame = -1

Query: 1158 RGMGSRLSNGEVMRGIFIKHVLEDSPAGKNGTLKPGDRIIEVDGMDLRDASHEQAVEAIR 1217
            RG G++   G+   GIFI  V+E   A ++G +   DR++ V+  +L D +HE+AV A++
Sbjct: 398  RGKGNQHIPGD--NGIFITKVIEGGSAEQDGRIAVMDRLLAVNEHNLEDVTHEEAVAALK 225

Query: 1218 KAGNPVVFMV 1227
              G+ V   +
Sbjct: 224  STGDVVRLTI 195

 Score = 41.6 bits (96), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 22/49 (44%), Positives = 28/49 (57%)
 Frame = -2

Query: 2005 FAKGAAAEDGRLKRGDQIIAVNGQSLEGVTHEEAVAILKRTKGTVTLMV 2053
            +  GAAAEDGRL+  D I+ V  + +   TH  AV  LKR+   V L V
Sbjct: 628  YRGGAAAEDGRLRLNDIIVKVGTEDVSNTTHTAAVDALKRSGNRVYLQV 482

 Score = 41.2 bits (95), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 18/46 (39%), Positives = 31/46 (67%)
 Frame = -1

Query: 1018 GVIVRSIIHGGAISRDGRIAVGDCILSINEESTISLTNAQARAMLR 1063
            G+ +  +I GG+  +DGRIAV D +L++NE +   +T+ +A A L+
Sbjct: 362  GIFITKVIEGGSAEQDGRIAVMDRLLAVNEHNLEDVTHEEAVAALK 225

 Score = 37.7 bits (86), Expect = 0.042,   Method: Compositional matrix adjust.
 Identities = 18/49 (36%), Positives = 27/49 (55%)
 Frame = -2

Query: 288 GGVADQHGRLCSGDHILKIGDTDLAGMSSEQVAQVLRQCGNRVKLMIAR 336
           GG A + GRL   D I+K+G  D++  +       L++ GNRV L + R
Sbjct: 622 GGAAAEDGRLRLNDIIVKVGTEDVSNTTHTAAVDALKRSGNRVYLQVKR 476

 Score = 37.7 bits (86), Expect = 0.050,   Method: Compositional matrix adjust.
 Identities = 19/57 (33%), Positives = 33/57 (57%)
 Frame = -1

Query: 1492 NGVMIESLTEHGGAAKDGRLKPGDHILAVDDEVVAGCPVEKFISLLKTAKATVKLTV 1548
            NG+ I  + E G A +DGR+   D +LAV++  +     E+ ++ LK+    V+LT+
Sbjct: 365  NGIFITKVIEGGSAEQDGRIAVMDRLLAVNEHNLEDVTHEEAVAALKSTGDVVRLTI 195

 Score = 37.4 bits (85), Expect = 0.056,   Method: Compositional matrix adjust.
 Identities = 23/52 (44%), Positives = 28/52 (53%)
 Frame = -2

Query: 1741 KGGIADADGRLMQGDQILMVNGEDVRHATQEAVAALLKCSLGAVTLEVGRVK 1792
            +GG A  DGRL   D I+ V  EDV + T  A    LK S   V L+V R+K
Sbjct: 625  RGGAAAEDGRLRLNDIIVKVGTEDVSNTTHTAAVDALKRSGNRVYLQVKRLK 470

 Score = 34.3 bits (77), Expect = 0.55,   Method: Compositional matrix adjust.
 Identities = 16/57 (28%), Positives = 30/57 (52%)
 Frame = -1

Query: 1363 VFIVGIDPTGAAGRDGRLQIADELLEINGQILYGRSHQNASSIIKCAPSKVKIIFIR 1419
            +FI  +   G+A +DGR+ + D LL +N   L   +H+ A + +K     V++   +
Sbjct: 359  IFITKVIEGGSAEQDGRIAVMDRLLAVNEHNLEDVTHEEAVAALKSTGDVVRLTIAK 189
>01502
          Length = 1949

 Score = 45.8 bits (107), Expect = 2e-04,   Method: Composition-based stats.
 Identities = 23/57 (40%), Positives = 39/57 (68%)
 Frame = +1

Query: 1171 RGIFIKHVLEDSPAGKNGTLKPGDRIIEVDGMDLRDASHEQAVEAIRKAGNPVVFMV 1227
            +GI++  + E+SPA + G L+  D+I++++G D    +H+QAVE IRK   PV+ M+
Sbjct: 31   KGIYVTFIYENSPAARCG-LQLHDKILQLNGKDFTVVTHKQAVENIRK--KPVLKML 192

 Score = 40.0 bits (92), Expect = 0.010,   Method: Composition-based stats.
 Identities = 25/81 (30%), Positives = 41/81 (50%)
 Frame = +1

Query: 1638 AIIIHEVYEEGAACKDGRLWAGDQILEVNGIDLRKATHDEAINVLRQTPQRVRLTLYRDE 1697
             I +  +YE   A + G L   D+IL++NG D    TH +A+  +R+ P  +++ +YR  
Sbjct: 34   GIYVTFIYENSPAARCG-LQLHDKILQLNGKDFTVVTHKQAVENIRKKPV-LKMLVYRKG 207

Query: 1698 APYKEEDVCDTFTIELQKRPG 1718
             P            +LQK+PG
Sbjct: 208  VP------------QLQKQPG 234

 Score = 32.0 bits (71), Expect = 2.9,   Method: Composition-based stats.
 Identities = 17/49 (34%), Positives = 29/49 (59%)
 Frame = +1

Query: 1996 DLPIYVKTVFAKGAAAEDGRLKRGDQIIAVNGQSLEGVTHEEAVAILKR 2044
            D  IYV  ++    AA  G L+  D+I+ +NG+    VTH++AV  +++
Sbjct: 28   DKGIYVTFIYENSPAARCG-LQLHDKILQLNGKDFTVVTHKQAVENIRK 171
>02951
          Length = 1076

 Score = 45.4 bits (106), Expect = 2e-04,   Method: Composition-based stats.
 Identities = 23/57 (40%), Positives = 39/57 (68%)
 Frame = +2

Query: 1171 RGIFIKHVLEDSPAGKNGTLKPGDRIIEVDGMDLRDASHEQAVEAIRKAGNPVVFMV 1227
            +GI++  + E+SPA + G L+  D+I++++G D    +H+QAVE IRK   PV+ M+
Sbjct: 17   KGIYVTFIYENSPAARCG-LQLHDKILQLNGKDFTVVTHKQAVENIRK--KPVLKML 178

 Score = 39.7 bits (91), Expect = 0.014,   Method: Composition-based stats.
 Identities = 25/81 (30%), Positives = 41/81 (50%)
 Frame = +2

Query: 1638 AIIIHEVYEEGAACKDGRLWAGDQILEVNGIDLRKATHDEAINVLRQTPQRVRLTLYRDE 1697
             I +  +YE   A + G L   D+IL++NG D    TH +A+  +R+ P  +++ +YR  
Sbjct: 20   GIYVTFIYENSPAARCG-LQLHDKILQLNGKDFTVVTHKQAVENIRKKPV-LKMLVYRKG 193

Query: 1698 APYKEEDVCDTFTIELQKRPG 1718
             P            +LQK+PG
Sbjct: 194  VP------------QLQKQPG 220

 Score = 31.6 bits (70), Expect = 3.6,   Method: Composition-based stats.
 Identities = 17/49 (34%), Positives = 29/49 (59%)
 Frame = +2

Query: 1996 DLPIYVKTVFAKGAAAEDGRLKRGDQIIAVNGQSLEGVTHEEAVAILKR 2044
            D  IYV  ++    AA  G L+  D+I+ +NG+    VTH++AV  +++
Sbjct: 14   DKGIYVTFIYENSPAARCG-LQLHDKILQLNGKDFTVVTHKQAVENIRK 157
>08480
          Length = 698

 Score = 44.3 bits (103), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 19/46 (41%), Positives = 33/46 (71%)
 Frame = -1

Query: 1183 PAGKNGTLKPGDRIIEVDGMDLRDASHEQAVEAIRKAGNPVVFMVQ 1228
            PA  +G L+ GD+I+ V+ +D+  A+HEQA +A+++AG+ V  + Q
Sbjct: 695  PADLSGDLRRGDKILSVNDVDVERATHEQAAQALKRAGDTVEIIAQ 558

 Score = 40.0 bits (92), Expect = 0.009,   Method: Compositional matrix adjust.
 Identities = 20/46 (43%), Positives = 28/46 (60%)
 Frame = -1

Query: 2008 GAAAEDGRLKRGDQIIAVNGQSLEGVTHEEAVAILKRTKGTVTLMV 2053
            G A   G L+RGD+I++VN   +E  THE+A   LKR   TV ++ 
Sbjct: 698  GPADLSGDLRRGDKILSVNDVDVERATHEQAAQALKRAGDTVEIIA 561

 Score = 37.0 bits (84), Expect = 0.079,   Method: Compositional matrix adjust.
 Identities = 24/67 (35%), Positives = 36/67 (53%)
 Frame = -1

Query: 1648 GAACKDGRLWAGDQILEVNGIDLRKATHDEAINVLRQTPQRVRLTLYRDEAPYKEEDVCD 1707
            G A   G L  GD+IL VN +D+ +ATH++A   L++    V +      A YK ED  +
Sbjct: 698  GPADLSGDLRRGDKILSVNDVDVERATHEQAAQALKRAGDTVEII-----AQYKPED-YN 537

Query: 1708 TFTIELQ 1714
             F  ++Q
Sbjct: 536  RFEAKIQ 516

 Score = 36.2 bits (82), Expect = 0.14,   Method: Compositional matrix adjust.
 Identities = 20/50 (40%), Positives = 31/50 (62%)
 Frame = -1

Query: 730 GIAEKDGRLFPGDRLMFVNDINLENSTLEEAVEALKGAPSGMVRIGVAKP 779
           G A+  G L  GD+++ VND+++E +T E+A +ALK A   +  I   KP
Sbjct: 698 GPADLSGDLRRGDKILSVNDVDVERATHEQAAQALKRAGDTVEIIAQYKP 549

 Score = 32.3 bits (72), Expect = 2.1,   Method: Compositional matrix adjust.
 Identities = 16/40 (40%), Positives = 27/40 (67%)
 Frame = -1

Query: 181 GRLKETDQILAINGQVLDQTITHQQAISILQKAKDTVQLV 220
           G L+  D+IL++N  V  +  TH+QA   L++A DTV+++
Sbjct: 680 GDLRRGDKILSVN-DVDVERATHEQAAQALKRAGDTVEII 564
>03499
          Length = 1247

 Score = 43.9 bits (102), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 23/57 (40%), Positives = 36/57 (63%), Gaps = 2/57 (3%)
 Frame = -3

Query: 571 IRSVLPEGPVGHSGKLFSGDELLEVNGINLLGENHQDVVNILKELPI--DVTMVCCR 625
           I++V+P GP   +GKL +GD ++ VN   +LG  HQDVV++ + +     VT+  CR
Sbjct: 894 IKNVVPNGPAYLNGKLKTGDVIVFVNTTCVLGYTHQDVVSLFQTISPGETVTLEICR 724

 Score = 38.9 bits (89), Expect = 0.020,   Method: Compositional matrix adjust.
 Identities = 22/88 (25%), Positives = 41/88 (46%), Gaps = 2/88 (2%)
 Frame = -3

Query: 1322 WKN--IQERYGSLTGQLHVIELEKGQSGLGLSLAGNKDRTRMSVFIVGIDPTGAAGRDGR 1379
            WK     ++ G L G+     L K   G G ++ G+       + I  + P G A  +G+
Sbjct: 1029 WKKPFFTKQPGELQGEFVKTSLVKSVRGFGFTIVGSDHPDTEFLQIKNVVPNGPAYLNGK 850

Query: 1380 LQIADELLEINGQILYGRSHQNASSIIK 1407
            L+  D ++ +N   + G +HQ+  S+ +
Sbjct: 849  LKTGDVIVFVNTTCVLGYTHQDVVSLFQ 766

 Score = 38.9 bits (89), Expect = 0.021,   Method: Compositional matrix adjust.
 Identities = 26/88 (29%), Positives = 44/88 (50%), Gaps = 1/88 (1%)
 Frame = -3

Query: 696 LEKGSRGLGFSILDYQDPIDPANTVIVIRSLVPGGIAEKDGRLFPGDRLMFVNDINLENS 755
           L K  RG GF+I+    P       + I+++VP G A  +G+L  GD ++FVN   +   
Sbjct: 966 LVKSVRGFGFTIVGSDHP---DTEFLQIKNVVPNGPAYLNGKLKTGDVIVFVNTTCVLGY 796

Query: 756 TLEEAVEALKG-APSGMVRIGVAKPLPL 782
           T ++ V   +  +P   V + + +  PL
Sbjct: 795 THQDVVSLFQTISPGETVTLEICRGYPL 712

 Score = 32.3 bits (72), Expect = 2.0,   Method: Compositional matrix adjust.
 Identities = 18/58 (31%), Positives = 31/58 (53%), Gaps = 2/58 (3%)
 Frame = -3

Query: 282 VKTILPGGVADQHGRLCSGDHILKIGDTDLAGMSSEQVAQVLRQC--GNRVKLMIARG 337
           +K ++P G A  +G+L +GD I+ +  T + G + + V  + +    G  V L I RG
Sbjct: 894 IKNVVPNGPAYLNGKLKTGDVIVFVNTTCVLGYTHQDVVSLFQTISPGETVTLEICRG 721
>38751
          Length = 329

 Score = 40.4 bits (93), Expect = 0.007,   Method: Composition-based stats.
 Identities = 23/58 (39%), Positives = 32/58 (55%)
 Frame = +3

Query: 1626 LSIVGGSDTLLGAIIIHEVYEEGAACKDGRLWAGDQILEVNGIDLRKATHDEAINVLR 1683
            + I GG +   G  I+  V EEG   +   L  GD+IL+VNG D    TH EA+ ++R
Sbjct: 3    VGIKGGKE--YGTPIVVYVIEEGCQAEQQGLNIGDRILDVNGTDFTHLTHAEAVTIMR 170

 Score = 40.4 bits (93), Expect = 0.007,   Method: Composition-based stats.
 Identities = 19/48 (39%), Positives = 30/48 (62%)
 Frame = +3

Query: 1874 PIFIAMMHPNGVAAQTQKLRVGDRIVTICGTSTDGMTHTQAVNLMKNA 1921
            PI + ++   G  A+ Q L +GDRI+ + GT    +TH +AV +M+NA
Sbjct: 36   PIVVYVIE-EGCQAEQQGLNIGDRILDVNGTDFTHLTHAEAVTIMRNA 176

 Score = 36.6 bits (83), Expect = 0.12,   Method: Composition-based stats.
 Identities = 24/60 (40%), Positives = 31/60 (51%), Gaps = 2/60 (3%)
 Frame = +3

Query: 1986 IVGG--YGSPHGDLPIYVKTVFAKGAAAEDGRLKRGDQIIAVNGQSLEGVTHEEAVAILK 2043
            I GG  YG+P       V  V  +G  AE   L  GD+I+ VNG     +TH EAV I++
Sbjct: 9    IKGGKEYGTP------IVVYVIEEGCQAEQQGLNIGDRILDVNGTDFTHLTHAEAVTIMR 170
>39267
          Length = 456

 Score = 36.2 bits (82), Expect = 0.14,   Method: Compositional matrix adjust.
 Identities = 23/74 (31%), Positives = 38/74 (51%)
 Frame = +1

Query: 1981 GLGFSIVGGYGSPHGDLPIYVKTVFAKGAAAEDGRLKRGDQIIAVNGQSLEGVTHEEAVA 2040
            GLGF+I G          IYV  +  +G A+E G++  GD+I +V   + + + +E+A+ 
Sbjct: 115  GLGFNISGNMRDG-----IYVSQLHNRGPASESGKIHVGDRIQSVT-IAYDNIVYEDALT 276

Query: 2041 ILKRTKGTVTLMVL 2054
            IL        L+ L
Sbjct: 277  ILSYASPYPVLLTL 318

 Score = 30.8 bits (68), Expect = 5.5,   Method: Compositional matrix adjust.
 Identities = 19/61 (31%), Positives = 32/61 (52%), Gaps = 1/61 (1%)
 Frame = +1

Query: 373 ESETFDVEL-TKNVQGLGITIAGYIGDKKLEPSGIFVKSITKSSAVEHDGRIQIGDQIIA 431
           E+ T  V L ++++ GLG  I+G + D      GI+V  +         G+I +GD+I +
Sbjct: 70  EAATESVWLHSQDIIGLGFNISGNMRD------GIYVSQLHNRGPASESGKIHVGDRIQS 231

Query: 432 V 432
           V
Sbjct: 232 V 234
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|153945724|ref|NP_033171.2| neuroplastin [Mus
musculus]
         (281 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

38127                                                                  61   4e-10
11855                                                                  52   3e-07
25766                                                                  39   0.002
08294                                                                  39   0.003
29990                                                                  36   0.019
18345                                                                  29   1.9  
02198                                                                  28   4.7  
06752                                                                  28   4.8  
>38127
          Length = 860

 Score = 61.2 bits (147), Expect = 4e-10,   Method: Compositional matrix adjust.
 Identities = 54/209 (25%), Positives = 93/209 (44%), Gaps = 13/209 (6%)
 Frame = -1

Query: 83  NMEYRINKPRAEDSGEYHCVYHFVSAP-KANATIEVK--AAPDITGHKRSENKNEGQDAM 139
           N    I  PR   +G Y CV  +  A  K++ +++V   A P +    +S+N  + +  +
Sbjct: 806 NGTLEIQHPRRNFAGMYTCVAEYEEAGVKSSISVDVPFYAHPKVLPFDKSKNLVQDESLV 627

Query: 140 MYCKSVGYPHPEWIWRKKENGVFEEISNSSGRFFITNKENYTELSIVNLQIT------ED 193
           + CK +GYP P   W        E +  +  R+ +    +Y   SI   ++       +D
Sbjct: 626 IECKVLGYPKPVVSWYMDN---VEIVDGADSRYSLKPANSYDGASIEGAKLVIEEVQFDD 456

Query: 194 PGEYEC--NATNSIGSASVSTVL--RVRSHLAPLWPFLGILAEXXXXXXXXXXYEKRKRP 249
            GEY C  N T+     + + V+  RV++   P  PFLGI+AE          YEK++  
Sbjct: 455 AGEYTCMSNYTDKWPQFNSTQVILVRVKTSWRPCGPFLGIVAEVVVLCAIIFIYEKKRSK 276

Query: 250 DEVPDDDEPAGPMKTNSTNNHKDKNLRQR 278
           D   ++D      +  ++   K + +RQR
Sbjct: 275 DAPVEED----VNQETTSEEKKAEGVRQR 201
>11855
          Length = 1574

 Score = 52.0 bits (123), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 41/157 (26%), Positives = 68/157 (43%), Gaps = 20/157 (12%)
 Frame = +1

Query: 78  RKNASNMEYRINKPRAEDSGEYHCVYHFVSAPKANATIEVKA-----APDITGHKRSENK 132
           R +++     ++ P ++D GEY CV       +  +TI VK      +PD+T   +  ++
Sbjct: 130 RLSSTKSRLYLDCPTSQDEGEYTCVAETPFKRRVQSTI-VKVDTRHYSPDVTCMSKRGSR 306

Query: 133 NEGQDAMM---------------YCKSVGYPHPEWIWRKKENGVFEEISNSSGRFFITNK 177
            E     M               +C++ GYP P   W    N     + ++SG+F I   
Sbjct: 307 GEPARVYMWTVSRLELETTTVQLFCRASGYPEPTITWYDGRN---NSLPDNSGQFSIAVN 477

Query: 178 ENYTELSIVNLQITEDPGEYECNATNSIGSASVSTVL 214
               +L I ++  +E+ G Y C A N +GS SV   L
Sbjct: 478 ---GDLIIRDISWSENMGVYRCVAENELGSHSVQAFL 579
>25766
          Length = 469

 Score = 38.9 bits (89), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 20/67 (29%), Positives = 32/67 (47%), Gaps = 2/67 (2%)
 Frame = +1

Query: 93  AEDSGEYHCVYHFVSA--PKANATIEVKAAPDITGHKRSENKNEGQDAMMYCKSVGYPHP 150
           A D+G Y CV         +  AT+ + + P ++  +R+EN+  G     +C   G P P
Sbjct: 88  AADAGRYRCVITSSEGITSEGFATLRISSPPVVSVKQRNENRQVGSSVKFHCDVSGDPVP 267

Query: 151 EWIWRKK 157
           +  W KK
Sbjct: 268 QVRWEKK 288
>08294
          Length = 1849

 Score = 38.9 bits (89), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 31/127 (24%), Positives = 49/127 (38%), Gaps = 6/127 (4%)
 Frame = +2

Query: 98  EYHCVYHFVSAPKANATIEVKAA--PDITGHKRSENKNEGQDAMMYCKSVGYPHPEWIWR 155
           +Y CV         NATI +     P IT    +    EG  A+++C + G P P+  W 
Sbjct: 2   DYTCVATHPRQGVINATIHISIVEWPAITVKSNNITVFEGHSAILHCVAKGSPSPDIAWY 181

Query: 156 KKENGVFEEISNSSGRFFITNKENYTELSIVNLQI----TEDPGEYECNATNSIGSASVS 211
           +    +              N   YT      ++I     ED G Y C A N+ G  + +
Sbjct: 182 RDSQPILP------------NARRYTLFKNGTMKIRQVFMEDNGMYACVANNTAGPLAGT 325

Query: 212 TVLRVRS 218
           +   +R+
Sbjct: 326 SSFALRT 346
>29990
          Length = 434

 Score = 35.8 bits (81), Expect = 0.019,   Method: Compositional matrix adjust.
 Identities = 18/74 (24%), Positives = 33/74 (44%), Gaps = 5/74 (6%)
 Frame = +3

Query: 88  INKPRAEDSGEYHCVYHFVSAPKANATIEVK-----AAPDITGHKRSENKNEGQDAMMYC 142
           I   + +D G Y C+   V+    +  +E++      AP  T   +     EGQ   + C
Sbjct: 105 IEDAQDDDRGVYECIARNVAGETHSNQVELRYFGERVAPXFTQRPQDIVTVEGQTVQLVC 284

Query: 143 KSVGYPHPEWIWRK 156
           ++ G+P P + W +
Sbjct: 285 QASGHPRPTFSWTR 326
>18345
          Length = 461

 Score = 29.3 bits (64), Expect = 1.9,   Method: Compositional matrix adjust.
 Identities = 24/90 (26%), Positives = 34/90 (37%), Gaps = 1/90 (1%)
 Frame = +1

Query: 134 EGQDAMMYCKSVGYPHPEWIWRKKENGVFEEISNSSGRFFITNKENYTELSIVNLQITED 193
           EG  A + C   G P P+  W K+     +      G          T   +V   +T  
Sbjct: 154 EGDTATLVCNVTGVPSPDVTWYKRNTRQLDAQKERVGS---------TGPVLVMYNVTRH 306

Query: 194 PGE-YECNATNSIGSASVSTVLRVRSHLAP 222
             + YEC A N +  A V+  +RV    AP
Sbjct: 307 CDDIYECYADNGVPPA-VTKAIRVTVDYAP 393
>02198
          Length = 2568

 Score = 27.7 bits (60), Expect = 4.7,   Method: Compositional matrix adjust.
 Identities = 10/24 (41%), Positives = 18/24 (75%)
 Frame = +1

Query: 173  FITNKENYTELSIVNLQITEDPGE 196
            F TNK +YTE+S++ +Q+ E+  +
Sbjct: 1192 FFTNKVSYTEMSMIIIQVLENAQQ 1263
>06752
          Length = 2075

 Score = 27.7 bits (60), Expect = 4.8,   Method: Compositional matrix adjust.
 Identities = 15/36 (41%), Positives = 22/36 (61%), Gaps = 4/36 (11%)
 Frame = -1

Query: 170  GRFFITNKENYTELSIVNLQITEDP----GEYECNA 201
            G  F TNK +YTE S++ +Q+ E+      EY CN+
Sbjct: 1292 GNCFFTNKVSYTEKSMIIIQVLENVHTKFQEY*CNS 1185
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|21539623|ref|NP_081772.1| ankyrin repeat domain 33B
isoform 2 [Mus musculus]
         (477 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

00540                                                                  62   4e-10
25464                                                                  45   7e-05
02114                                                                  40   0.002
27108                                                                  40   0.002
20036                                                                  39   0.004
13462                                                                  39   0.006
27067                                                                  39   0.007
05924                                                                  38   0.010
02351                                                                  35   0.045
12417                                                                  34   0.11 
15772                                                                  34   0.13 
34789                                                                  34   0.16 
06253                                                                  33   0.31 
28691                                                                  32   0.38 
18216                                                                  32   0.71 
28494                                                                  31   1.0  
09214                                                                  31   1.1  
25470                                                                  31   1.3  
11317                                                                  30   2.6  
05396                                                                  30   2.9  
30463                                                                  30   3.1  
14005                                                                  29   3.6  
11295                                                                  29   4.6  
30217                                                                  28   6.6  
35952                                                                  28   8.3  
>00540
          Length = 3034

 Score = 62.4 bits (150), Expect = 4e-10,   Method: Compositional matrix adjust.
 Identities = 44/130 (33%), Positives = 67/130 (51%)
 Frame = -2

Query: 101  VRRGPSSEETGLIVACYHGFVDTVVALAECPHVDVNWQDSEGNTALITAAQAGHVTITNY 160
            V +   S  T L  ACY G ++ V  L E    ++   +S G+T L+ A   GH+ +  Y
Sbjct: 2991 VNQTTRSNSTPLRAACYDGHLEVVQFLVE-HKAEIEIANSHGHTCLMIACYRGHLDVVEY 2815

Query: 161  LLNYFPGLDLERRNIFGFTALMKAAMQGRTECVRALMMAGADVQARDPRRGLSPQEWAAY 220
            LL  + G  + RR++ G TAL  +A  G+   ++ L+  GA + A+D   G +P   AA 
Sbjct: 2814 LL--YLGAQVNRRSVKGNTALHDSAESGKLSIMKLLLSKGAKM-AKDA-YGQTPLSAAAM 2647

Query: 221  TGRAEAVRVI 230
            TG  E VR +
Sbjct: 2646 TGHEEIVRYL 2617

 Score = 49.7 bits (117), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 42/122 (34%), Positives = 62/122 (50%), Gaps = 7/122 (5%)
 Frame = -2

Query: 83   ATLLRAACAND----VGLL---RALVRRGPSSEETGLIVACYHGFVDTVVALAECPHVDV 135
            +T LRAAC +     V  L   +A +    S   T L++ACY G +D V  L       V
Sbjct: 2967 STPLRAACYDGHLEVVQFLVEHKAEIEIANSHGHTCLMIACYRGHLDVVEYLLYLG-AQV 2791

Query: 136  NWQDSEGNTALITAAQAGHVTITNYLLNYFPGLDLERRNIFGFTALMKAAMQGRTECVRA 195
            N +  +GNTAL  +A++G ++I   LL+    +    ++ +G T L  AAM G  E VR 
Sbjct: 2790 NRRSVKGNTALHDSAESGKLSIMKLLLSKGAKM---AKDAYGQTPLSAAAMTGHEEIVRY 2620

Query: 196  LM 197
            L+
Sbjct: 2619 LI 2614
>25464
          Length = 440

 Score = 45.1 bits (105), Expect = 7e-05,   Method: Compositional matrix adjust.
 Identities = 38/130 (29%), Positives = 59/130 (45%), Gaps = 3/130 (2%)
 Frame = -3

Query: 110 TGLIVACYHGFVDTVVALAECPHVDVNWQDSEGNTALITAAQAGHVTITNYLLNYFP--G 167
           T L  AC +G  D V  + +   +D+N  D++GNT +  AA + +  I   L   F   G
Sbjct: 405 TALSYACLNGRQDIVRCILKEDVLDINEPDNDGNTPIHHAAISANPNIVRMLAEAFYKFG 226

Query: 168 LDLERRNIFGFTALMKAAMQGRTECVRALM-MAGADVQARDPRRGLSPQEWAAYTGRAEA 226
           L+ ++RN  G+T L+ A   G       L+    A    RD    L+  EW   T + + 
Sbjct: 225 LNPDKRNKLGYTPLLLACKGGNYVSAYTLLTTTKASPTLRDGEFHLNATEWIQRTHQMQ- 49

Query: 227 VRVIQRLMER 236
               + +MER
Sbjct: 48  ----ENVMER 31
>02114
          Length = 1072

 Score = 40.4 bits (93), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 29/83 (34%), Positives = 42/83 (50%)
 Frame = +1

Query: 114 VACYHGFVDTVVALAECPHVDVNWQDSEGNTALITAAQAGHVTITNYLLNYFPGLDLERR 173
           +A Y+G +D +  L E   V++N +D +GNT    AA  GH+ I  +L+    G D+E  
Sbjct: 733 MAAYNGELDHLRILVENGVVNINERDDKGNTLAHRAAGQGHLNILQWLVEM--GADVEIS 906

Query: 174 NIFGFTALMKAAMQGRTECVRAL 196
           N  G TA   A       CV+ L
Sbjct: 907 NGAGETARDIARRFAHLACVKLL 975
>27108
          Length = 449

 Score = 40.0 bits (92), Expect = 0.002,   Method: Composition-based stats.
 Identities = 36/133 (27%), Positives = 47/133 (35%), Gaps = 18/133 (13%)
 Frame = -3

Query: 93  DVGLLRALVRRGPSSEETGLIVACYHGFVDTVVALAECPHVDVNWQDSEGNTALITAAQA 152
           D  L    V +     ET LI A     +  +  L   P VD+N QD  G TAL  A   
Sbjct: 432 DTSLTADKVNKKNHKGETMLIRAAIKNNLSLLKHLLTVPGVDINSQDYAGWTALHEACNH 253

Query: 153 GHVTITNYLLNYFPG------------------LDLERRNIFGFTALMKAAMQGRTECVR 194
           GH+     LL + P                   +D+   N  G TAL  A        V+
Sbjct: 252 GHLECARALLKFVPSATLDSFFQSGKNRGKVRKVDMHLANQEGITALHDAVSMNHVSVVK 73

Query: 195 ALMMAGADVQARD 207
            L+  G     +D
Sbjct: 72  LLLKYGGSSLLKD 34

 Score = 35.0 bits (79), Expect = 0.069,   Method: Composition-based stats.
 Identities = 36/140 (25%), Positives = 59/140 (42%), Gaps = 27/140 (19%)
 Frame = -3

Query: 69  SVSAESVPEGVPEAATLL-RAACANDVGLLRAL-------VRRGPSSEETGLIVACYHGF 120
           S++A+ V +   +  T+L RAA  N++ LL+ L       +     +  T L  AC HG 
Sbjct: 426 SLTADKVNKKNHKGETMLIRAAIKNNLSLLKHLLTVPGVDINSQDYAGWTALHEACNHGH 247

Query: 121 VDTVVAL-------------------AECPHVDVNWQDSEGNTALITAAQAGHVTITNYL 161
           ++   AL                    +   VD++  + EG TAL  A    HV++   L
Sbjct: 246 LECARALLKFVPSATLDSFFQSGKNRGKVRKVDMHLANQEGITALHDAVSMNHVSVVKLL 67

Query: 162 LNYFPGLDLERRNIFGFTAL 181
           L Y     L+ + + G T +
Sbjct: 66  LKYGGSSLLKDKTVSGDTVM 7
>20036
          Length = 1849

 Score = 39.3 bits (90), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 24/68 (35%), Positives = 31/68 (45%), Gaps = 4/68 (5%)
 Frame = +3

Query: 110  TGLIVACYHGFVDTVVALAECPHVDVNWQDSEGNTALITAAQAGHVTITNYLLNYF---- 165
            T L+ AC HG    V  L   PH D    D+E +TAL  A +A H  I   L  +     
Sbjct: 1206 TALMCACEHGHTAIVQLLLAQPHCDATLTDNENSTALSIAMEASHKDIGVILYKHLNFSS 1385

Query: 166  PGLDLERR 173
            PG   +R+
Sbjct: 1386 PGFQKKRK 1409

 Score = 33.1 bits (74), Expect = 0.25,   Method: Compositional matrix adjust.
 Identities = 21/54 (38%), Positives = 28/54 (51%)
 Frame = +3

Query: 109  ETGLIVACYHGFVDTVVALAECPHVDVNWQDSEGNTALITAAQAGHVTITNYLL 162
            +T L++A      D V  L E    D N QD +G+TAL+ A + GH  I   LL
Sbjct: 1104 QTALMLATSQCRTDMVELLLETG-ADCNQQDFDGSTALMCACEHGHTAIVQLLL 1262

 Score = 29.6 bits (65), Expect = 2.7,   Method: Compositional matrix adjust.
 Identities = 28/88 (31%), Positives = 38/88 (43%), Gaps = 2/88 (2%)
 Frame = +3

Query: 177  GFTALMKAAMQGRTECVRALMMAGADVQARDPRRGLSPQEWAAYTGRAEAVRVIQRLMER 236
            G TALM A  Q RT+ V  L+  GAD   +D   G +    A   G      ++Q L+ +
Sbjct: 1101 GQTALMLATSQCRTDMVELLLETGADCNQQDF-DGSTALMCACEHGH---TAIVQLLLAQ 1268

Query: 237  P-CPEQFGD-KYKLELPLPAEAVLKKSG 262
            P C     D +    L +  EA  K  G
Sbjct: 1269 PHCDATLTDNENSTALSIAMEASHKDIG 1352
>13462
          Length = 1388

 Score = 38.5 bits (88), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 41/132 (31%), Positives = 61/132 (46%), Gaps = 13/132 (9%)
 Frame = +3

Query: 84  TLLRAAC-ANDVGLLRALVRRGPSSEETGLIV-------ACYH-----GFVDTVVALAEC 130
           TLL  AC  N   L+  L++RG   +   L +       A +H     G V  ++A    
Sbjct: 81  TLLCVACKLNRADLVPVLLQRGALPDLPSLYLNKRPLHYASHHSNGNLGIVSMLLAYGAQ 260

Query: 131 PHVDVNWQDSEGNTALITAAQAGHVTITNYLLNYFPGLDLERRNIFGFTALMKAAMQGRT 190
           P+V    QD +GNTAL  A    +V +   LL +  G D+   +I   T L++A +    
Sbjct: 261 PNV----QDEDGNTALHLACSESNVDVVRLLLEW--GGDVAVADIDNETPLVRACLANSV 422

Query: 191 ECVRALMMAGAD 202
           E V  L+ AG+D
Sbjct: 423 ELVDLLLHAGSD 458
>27067
          Length = 409

 Score = 38.5 bits (88), Expect = 0.007,   Method: Composition-based stats.
 Identities = 22/69 (31%), Positives = 37/69 (53%)
 Frame = +1

Query: 141 EGNTALITAAQAGHVTITNYLLNYFPGLDLERRNIFGFTALMKAAMQGRTECVRALMMAG 200
           +G++A+  A +  +  I  YLL   PGL+    N    T +M+AA +GR EC+  L+  G
Sbjct: 22  KGSSAVHEAIKVNNTDILRYLLT-VPGLECNAVNASQKTPVMEAASRGRIECLTMLLDHG 198

Query: 201 ADVQARDPR 209
            + +  + R
Sbjct: 199 CNTEGENIR 225
>05924
          Length = 704

 Score = 37.7 bits (86), Expect = 0.010,   Method: Compositional matrix adjust.
 Identities = 39/141 (27%), Positives = 61/141 (43%), Gaps = 6/141 (4%)
 Frame = +1

Query: 96  LLRALVRRGPSSEETG------LIVACYHGFVDTVVALAECPHVDVNWQDSEGNTALITA 149
           L++ L++ G ++  T       L +AC  G+ + V  L      DVN +  +G T L  A
Sbjct: 109 LVQMLIKAGANANSTNQDGRTALHLACRGGYTNIVQILIAAG-TDVNRRTVDGKTCLHVA 285

Query: 150 AQAGHVTITNYLLNYFPGLDLERRNIFGFTALMKAAMQGRTECVRALMMAGADVQARDPR 209
              GH  +   L+N   G D+   +  G + L  AA    T  +  L+ AGA V  R  +
Sbjct: 286 VWRGHTEVVVKLVN--AGADVNIPDSVGCSPLYWAARSNYTAILTVLVNAGAKVNYR-VK 456

Query: 210 RGLSPQEWAAYTGRAEAVRVI 230
              +P   A + G    VR +
Sbjct: 457 SKWTPLHAALHLGHMGVVRYL 519
>02351
          Length = 939

 Score = 35.4 bits (80), Expect = 0.045,   Method: Compositional matrix adjust.
 Identities = 33/99 (33%), Positives = 41/99 (41%), Gaps = 5/99 (5%)
 Frame = +3

Query: 122 DTVVALAECPHVDVN--WQDSEGNTALITAAQAGHVTITNYLLNYFPGL---DLERRNIF 176
           + ++ L      D+N  +   +G TAL  AA  G+V     LL Y   +   D E RN  
Sbjct: 402 NIIIILGHAASDDINSPYGKDDGRTALHIAAALGNVVYVQLLLWYCANVKVVDHEGRN-- 575

Query: 177 GFTALMKAAMQGRTECVRALMMAGADVQARDPRRGLSPQ 215
              AL  A   G  EC   L  AG    A  PRR  S Q
Sbjct: 576 ---ALWYARTSGSVECTDLLAAAGCPDTATLPRRRGSLQ 683
>12417
          Length = 954

 Score = 34.3 bits (77), Expect = 0.11,   Method: Compositional matrix adjust.
 Identities = 23/65 (35%), Positives = 30/65 (46%)
 Frame = +2

Query: 134 DVNWQDSEGNTALITAAQAGHVTITNYLLNYFPGLDLERRNIFGFTALMKAAMQGRTECV 193
           DVN     G T L  A+  GH  I + LL    G D++  + +G TAL  A   G   C 
Sbjct: 308 DVNSATEHGRTPLHXASAQGHGHIVDLLLE--KGADIDAEDDYGDTALSIADQFGFKSCG 481

Query: 194 RALMM 198
           R L +
Sbjct: 482 RXLFL 496
>15772
          Length = 1282

 Score = 33.9 bits (76), Expect = 0.13,   Method: Compositional matrix adjust.
 Identities = 27/98 (27%), Positives = 44/98 (44%)
 Frame = -3

Query: 149  AAQAGHVTITNYLLNYFPGLDLERRNIFGFTALMKAAMQGRTECVRALMMAGADVQARDP 208
            A+   +  + +Y+ +    ++L+  +    TAL  A  +G  EC+R L+  GA   AR  
Sbjct: 1262 ASTGDYDALEDYVKSGIYDVNLKDPDAGNKTALHWACQKGFVECIRLLLDHGAKGTAR-T 1086

Query: 209  RRGLSPQEWAAYTGRAEAVRVIQRLMERPCPEQFGDKY 246
              G +P   AA   R  A+R +   +    P    DKY
Sbjct: 1085 DTGWTPAHCAAECNRVTALRALHAAL---VPVDLTDKY 981
>34789
          Length = 1249

 Score = 33.9 bits (76), Expect = 0.16,   Method: Compositional matrix adjust.
 Identities = 28/106 (26%), Positives = 42/106 (39%), Gaps = 30/106 (28%)
 Frame = +3

Query: 135 VNWQDSEGNTALITAAQAGHVTITNYLL-------------NYFP--------------- 166
           +N   S+G+TAL  A   G+V + +YLL             N+                 
Sbjct: 57  LNQMGSDGSTALFMAVYDGNVELVDYLLKNGANPHFSSQHGNFLHAAVLSQSVPLIQRAL 236

Query: 167 --GLDLERRNIFGFTALMKAAMQGRTECVRALMMAGADVQARDPRR 210
             G D+   N+FG + L   +     E  R L+  GAD+ +RD  R
Sbjct: 237 DLGCDINEHNMFGNSPLTLVSRLDLPEACRMLVEHGADLNSRDRYR 374
>06253
          Length = 1049

 Score = 32.7 bits (73), Expect = 0.31,   Method: Compositional matrix adjust.
 Identities = 35/116 (30%), Positives = 49/116 (42%), Gaps = 1/116 (0%)
 Frame = -1

Query: 144  TALITAAQAGHVTITNYLLNYFPGLDLERRNIFGFTALMKAAMQGRTECVRALMMAGADV 203
            T L  AA  G   +  +LL    G ++  R+  G   L  A   G  E V+ L+  GAD 
Sbjct: 1040 TPLHFAAGFGRKDVVEHLLE--NGANVHARDDGGLIPLHNACSFGHAEVVQLLLRHGADP 867

Query: 204  QARDPRRGLSPQEWAAYTGRAEAVRVIQRLMERPCPEQFGDKYKLELP-LPAEAVL 258
             ARD     +P   AA  G+ +   V+ +    P       K  L+L    A+AVL
Sbjct: 866  NARD-NWNYTPLHEAAIKGKIDVCIVLLQQCADPNIRNTDGKTALDLADASAKAVL 702
>28691
          Length = 562

 Score = 32.3 bits (72), Expect = 0.38,   Method: Compositional matrix adjust.
 Identities = 28/100 (28%), Positives = 44/100 (44%), Gaps = 2/100 (2%)
 Frame = +1

Query: 177 GFTALMKAAMQGRTECVRALMMAGADVQARDPR--RGLSPQEWAAYTGRAEAVRVIQRLM 234
           G  AL  AA     +C+  L+ AGADV A+ P   +G +    A   G A  V  +  L+
Sbjct: 118 GLPALHLAAKNKHVDCIPVLVQAGADVNAKGPSTIKGNTALHEAVSVG-ASNVDSVDALL 294

Query: 235 ERPCPEQFGDKYKLELPLPAEAVLKKSGSKNCLQRFTAFL 274
                +   +    E    A  +  K+G +N ++RF A +
Sbjct: 295 SCGADQNIXN----EKGETAYDLASKAGYENIVKRFAAAM 402
>18216
          Length = 472

 Score = 31.6 bits (70), Expect = 0.71,   Method: Composition-based stats.
 Identities = 15/37 (40%), Positives = 23/37 (62%)
 Frame = +2

Query: 167 GLDLERRNIFGFTALMKAAMQGRTECVRALMMAGADV 203
           G+ +   + FG+TA M AA +G    V+ L+ AGAD+
Sbjct: 275 GVHVNAVDPFGWTAAMSAAFEGHLAVVQTLLEAGADL 385
>28494
          Length = 463

 Score = 31.2 bits (69), Expect = 1.0,   Method: Compositional matrix adjust.
 Identities = 20/64 (31%), Positives = 28/64 (43%)
 Frame = -1

Query: 167 GLDLERRNIFGFTALMKAAMQGRTECVRALMMAGADVQARDPRRGLSPQEWAAYTGRAEA 226
           G D+   N+ G TAL +A +    + V  L+   ADV   D   G +P    A  G  E 
Sbjct: 250 GADINTANVDGLTALHQACIDDNLDMVEFLVEQNADVDVCD-NEGWTPLHATASCGFTEI 74

Query: 227 VRVI 230
            R +
Sbjct: 73  ARYL 62
>09214
          Length = 2116

 Score = 31.2 bits (69), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 17/39 (43%), Positives = 23/39 (58%), Gaps = 1/39 (2%)
 Frame = -3

Query: 127  LAECPHVDVNWQDS-EGNTALITAAQAGHVTITNYLLNY 164
            L E  +VDVN Q+   G TAL   A+  H T+  YLL++
Sbjct: 1658 LVEVKNVDVNAQNKMNGRTALHWGAKRDHQTVVQYLLSH 1542
>25470
          Length = 400

 Score = 30.8 bits (68), Expect = 1.3,   Method: Composition-based stats.
 Identities = 33/111 (29%), Positives = 47/111 (42%), Gaps = 1/111 (0%)
 Frame = -3

Query: 149 AAQAGHVTITNYLLNYFPGLDLERRNIFGFTALMKAAMQGRTECVRALMMAGADVQARDP 208
           AA  G   +  +LL    G ++  R+  G   L  A   G  E V+ L+  GAD  ARD 
Sbjct: 377 AAGFGRKDVVEHLLE--NGANVHARDDGGLIPLHNACSFGHAEVVQLLLRHGADPNARD- 207

Query: 209 RRGLSPQEWAAYTGRAEAVRVIQRLMERPCPEQFGDKYKLELP-LPAEAVL 258
               +P   AA  G+ +   V+ +    P       K  L+L    A+AVL
Sbjct: 206 NWNYTPLHEAAIKGKIDVCIVLLQQCADPNIRNTDGKTALDLADASAKAVL 54
>11317
          Length = 537

 Score = 29.6 bits (65), Expect = 2.6,   Method: Compositional matrix adjust.
 Identities = 10/24 (41%), Positives = 16/24 (66%)
 Frame = +3

Query: 135 VNWQDSEGNTALITAAQAGHVTIT 158
           +NW  SEG+T  I   + GHV+++
Sbjct: 453 LNWLHSEGSTCFILLTEKGHVSVS 524
>05396
          Length = 1865

 Score = 29.6 bits (65), Expect = 2.9,   Method: Compositional matrix adjust.
 Identities = 21/79 (26%), Positives = 38/79 (48%)
 Frame = +3

Query: 167  GLDLERRNIFGFTALMKAAMQGRTECVRALMMAGADVQARDPRRGLSPQEWAAYTGRAEA 226
            G+D+ + +  G TAL  A+ +G+ + V  L+           R G +P + A    + EA
Sbjct: 1353 GMDMSQPDYDGRTALHVASAEGQLQVVEFLLDRCKCSPFLVDRWGFTPLDDAVRFEKHEA 1532

Query: 227  VRVIQRLMERPCPEQFGDK 245
              +++  M +  P+ F DK
Sbjct: 1533 AELLKERMMQENPDYFHDK 1589
>30463
          Length = 412

 Score = 29.6 bits (65), Expect = 3.1,   Method: Composition-based stats.
 Identities = 17/54 (31%), Positives = 26/54 (48%)
 Frame = -1

Query: 177 GFTALMKAAMQGRTECVRALMMAGADVQARDPRRGLSPQEWAAYTGRAEAVRVI 230
           G+TA   AAM G +  V  L + GA +  R   +  +P   A+  G  E V+ +
Sbjct: 388 GYTATHLAAMNGHSNAVMVLNIMGASIDCRTVDKQ-TPLHLASSAGHIECVKCL 230
>14005
          Length = 1745

 Score = 29.3 bits (64), Expect = 3.6,   Method: Compositional matrix adjust.
 Identities = 41/148 (27%), Positives = 66/148 (44%), Gaps = 10/148 (6%)
 Frame = -1

Query: 81   EAATLLRAACAND---VGLLRALVRRGPS-------SEETGLIVACYHGFVDTVVALAEC 130
            +  T L  AC ND   V LL  L+R G +       +  T +  AC    ++ +  L   
Sbjct: 1445 DGKTPLVVACKNDKAEVALL--LIRSGANVNVSCDITANTPVHFACQRPNIELLKRLV-L 1275

Query: 131  PHVDVNWQDSEGNTALITAAQAGHVTITNYLLNYFPGLDLERRNIFGFTALMKAAMQGRT 190
               DV+  +++G+TAL  A+  G      YLL+ F   ++    + G  AL  A      
Sbjct: 1274 HGADVDKPNAKGHTALHVASVRGFKQHVIYLLD-FCDAEVNAATLKGNNALHIACRGKHA 1098

Query: 191  ECVRALMMAGADVQARDPRRGLSPQEWA 218
            + V  L+  GA+   R+ +RG +P+  A
Sbjct: 1097 DLVELLLHKGANPAQRN-QRGWTPRNSA 1017
>11295
          Length = 1179

 Score = 28.9 bits (63), Expect = 4.6,   Method: Compositional matrix adjust.
 Identities = 15/27 (55%), Positives = 16/27 (59%)
 Frame = +1

Query: 136 NWQDSEGNTALITAAQAGHVTITNYLL 162
           N  D EG T L  A+  GHVTI N LL
Sbjct: 754 NVVDDEGITPLYIASCEGHVTIVNILL 834
>30217
          Length = 412

 Score = 28.5 bits (62), Expect = 6.6,   Method: Composition-based stats.
 Identities = 22/56 (39%), Positives = 27/56 (48%), Gaps = 2/56 (3%)
 Frame = -3

Query: 109 ETGLIVACYHGFVDTVVALAE-CPH-VDVNWQDSEGNTALITAAQAGHVTITNYLL 162
           +T L +AC  G+VD V AL    PH   +N Q+    T L  AA     TI   LL
Sbjct: 203 DTPLHLACISGYVDVVAALIRMAPHPCLLNIQNDVAQTPLHLAALTAQPTILRMLL 36
>35952
          Length = 1624

 Score = 28.1 bits (61), Expect = 8.3,   Method: Compositional matrix adjust.
 Identities = 28/103 (27%), Positives = 46/103 (44%)
 Frame = -1

Query: 132 HVDVNWQDSEGNTALITAAQAGHVTITNYLLNYFPGLDLERRNIFGFTALMKAAMQGRTE 191
           + DVN +  +GNT L  A   G + +   L+      D+E   I           + + E
Sbjct: 901 NADVNARCFDGNTPLHVACCRGLIGMVALLMTAGALTDVENEEI---------PPEDKEE 749

Query: 192 CVRALMMAGADVQARDPRRGLSPQEWAAYTGRAEAVRVIQRLM 234
                  AG +  +R  RRGL P+++AA   R   +R+++ LM
Sbjct: 748 -------AGGETGSRKCRRGLLPRDYAAGKDR---LRILRMLM 650
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|33469051|ref|NP_878259.1| tubulin
polymerization-promoting protein [Mus musculus]
         (218 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

30376                                                                  61   4e-10
14594                                                                  31   0.34 
05303                                                                  30   0.56 
30279                                                                  29   1.5  
11245                                                                  28   3.5  
23204                                                                  27   5.1  
>30376
          Length = 463

 Score = 60.8 bits (146), Expect = 4e-10,   Method: Compositional matrix adjust.
 Identities = 38/52 (73%), Positives = 42/52 (80%)
 Frame = +2

Query: 162 VSRLTDTSKFTGSHKERFDQSGKGKGKAGRVDLVDESGYVPGYKHAGTYDQK 213
            +RLTDTSK+TGSHKERFD  GKGKGK GRV+  D SGYV  YK AGTYD+K
Sbjct: 92  TARLTDTSKYTGSHKERFDGEGKGKGKTGRVEEKDASGYVGNYKGAGTYDKK 247
>14594
          Length = 1014

 Score = 31.2 bits (69), Expect = 0.34,   Method: Compositional matrix adjust.
 Identities = 33/124 (26%), Positives = 56/124 (45%), Gaps = 2/124 (1%)
 Frame = +3

Query: 46  ELSALEEAFRRFAVHGDTRATGKEMHGKNWSKLCKDCHVIDGKNVTVTDVDIVFSKIKGK 105
           +++  +EAF  F   GD   T  E+ G     L        G+N T  ++  + +++   
Sbjct: 435 QVAEFKEAFSLFDKDGDGTITTSEL-GTVMRSL--------GQNPTENELQDMINEVDAD 587

Query: 106 SCRTITFEQFQEALEELAKKRFKDKSSEEAVREVHRLI--EGRAPVISGVTKAVSSPTVS 163
              TI FE+F   L  +A+K  KD   EE +RE  R+   +G   + +   + V +    
Sbjct: 588 GNGTIDFEEF---LHMMARK-MKDTDCEEELREAFRVFDKDGNGYISAAELRHVMTNLGE 755

Query: 164 RLTD 167
           +LTD
Sbjct: 756 KLTD 767
>05303
          Length = 782

 Score = 30.4 bits (67), Expect = 0.56,   Method: Compositional matrix adjust.
 Identities = 19/43 (44%), Positives = 20/43 (46%)
 Frame = +2

Query: 41  ATAAPELSALEEAFRRFAVHGDTRATGKEMHGKNWSKLCKDCH 83
            T A   S LEE FR F   G    TG E  G  W KL + CH
Sbjct: 344 PTPANRKSPLEENFRLFTNPG----TGTEXRGTRWWKLAEHCH 460
>30279
          Length = 612

 Score = 28.9 bits (63), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 26/86 (30%), Positives = 39/86 (45%)
 Frame = +1

Query: 102 IKGKSCRTITFEQFQEALEELAKKRFKDKSSEEAVREVHRLIEGRAPVISGVTKAVSSPT 161
           +K  +   ITF  F   L  LA     + + + A  E  R  + R          +S+  
Sbjct: 76  VKADNLEIITFNVFINHLTLLAPAVPANITVDSAWVEPSREKKKRY--------ELSNIR 231

Query: 162 VSRLTDTSKFTGSHKERFDQSGKGKG 187
           + R +D SKFT S +++FD SGK  G
Sbjct: 232 LIRRSDISKFTHSRRKQFDLSGKFGG 309
>11245
          Length = 993

 Score = 27.7 bits (60), Expect = 3.5,   Method: Compositional matrix adjust.
 Identities = 12/22 (54%), Positives = 14/22 (63%)
 Frame = +2

Query: 25  RAAKRLSLESEGANEGATAAPE 46
           R AKRL +   G NEG  +APE
Sbjct: 698 RVAKRLEVGMVGVNEGIISAPE 763
>23204
          Length = 1566

 Score = 27.3 bits (59), Expect = 5.1,   Method: Compositional matrix adjust.
 Identities = 13/23 (56%), Positives = 17/23 (73%)
 Frame = +2

Query: 142 LIEGRAPVISGVTKAVSSPTVSR 164
           L  G++ V SGVT A +SPT+SR
Sbjct: 407 LCRGKSSVKSGVTTAATSPTISR 475
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|41152116|ref|NP_957678.1| leucine rich repeat
containing 47 [Mus musculus]
         (581 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

17298                                                                  63   4e-10
09309                                                                  57   2e-08
34576                                                                  52   5e-07
05532                                                                  49   5e-06
30747                                                                  44   2e-04
19531                                                                  40   0.003
36727                                                                  33   0.32 
20480                                                                  31   1.6  
14078                                                                  30   3.0  
>17298
          Length = 476

 Score = 62.8 bits (151), Expect = 4e-10,   Method: Compositional matrix adjust.
 Identities = 30/93 (32%), Positives = 57/93 (61%), Gaps = 6/93 (6%)
 Frame = +3

Query: 174 LFRPGALPLL------SELAAADNCLRELSPDIAHLASLKTLDLSNNQLTEIPAELADCP 227
           ++ P  +P+L      S++ A +N + ++  D++ L  L  L+L++NQ+ E+P EL +C 
Sbjct: 198 VYCPRMVPVLAKCLTGSDIIANNNAITDVPADLSSLPHLNCLNLADNQIEELPNELCECT 377

Query: 228 KLKEINFRGNRLRDKRLEKMVGGCQTKSILEYL 260
           +LKE+   GN+++D+RL K       K +++YL
Sbjct: 378 RLKELKLSGNKIKDRRLVKFTEQNNLKQVMQYL 476

 Score = 33.5 bits (75), Expect = 0.27,   Method: Compositional matrix adjust.
 Identities = 16/36 (44%), Positives = 24/36 (66%)
 Frame = +3

Query: 132 QLQSLNLSGNRLRELPADLARCAPRLQSLNLTGNRL 167
            L  LNL+ N++ ELP +L  C  RL+ L L+GN++
Sbjct: 309 HLNCLNLADNQIEELPNELCECT-RLKELKLSGNKI 413
>09309
          Length = 1508

 Score = 57.0 bits (136), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 38/112 (33%), Positives = 56/112 (50%), Gaps = 2/112 (1%)
 Frame = +3

Query: 132 QLQSLNLSGNRLRELPADLARCAPR--LQSLNLTGNRLDAFPPELFRPGALPLLSELAAA 189
           Q ++++ SG     +PAD+   A    + S+N++ N+    P  LF    +  L+EL   
Sbjct: 357 QFKTMDFSGKNANAVPADMWEKAQEAAVTSVNISKNQFTQLPSNLFL--LVNSLTELNMG 530

Query: 190 DNCLRELSPDIAHLASLKTLDLSNNQLTEIPAELADCPKLKEINFRGNRLRD 241
            N L  LSPDI     L  LDL NN L+ +PAEL     L+E+    NR  +
Sbjct: 531 FNKLTGLSPDIGLFLKLTCLDLRNNGLSSLPAELCSMQALREVILSCNRFTE 686

 Score = 37.7 bits (86), Expect = 0.011,   Method: Compositional matrix adjust.
 Identities = 27/81 (33%), Positives = 43/81 (53%)
 Frame = +3

Query: 180 LPLLSELAAADNCLRELSPDIAHLASLKTLDLSNNQLTEIPAELADCPKLKEINFRGNRL 239
           L  L+ L   DN L +L  +I  L +L+ LDLSNN ++ +P  L     LK +   GN +
Sbjct: 15  LSTLNFLDVRDNKLAKLPDEITLLENLERLDLSNNDISMLPYSLGTINSLKSVILDGNPM 194

Query: 240 RDKRLEKMVGGCQTKSILEYL 260
           +  R + ++ G  T  + +YL
Sbjct: 195 KSIRRDIIMRG--TMELKKYL 251
>34576
          Length = 1496

 Score = 52.4 bits (124), Expect = 5e-07,   Method: Compositional matrix adjust.
 Identities = 43/121 (35%), Positives = 61/121 (50%), Gaps = 1/121 (0%)
 Frame = +2

Query: 132 QLQSLNLSGNRLRELPADLARCAPRLQSLNLTGNRLDAFPPELFRPG-ALPLLSELAAAD 190
           +L++L L GN L E+P +L     +L  L+L  N    FP    RP  ++  L  L  +D
Sbjct: 257 ELEALLLDGNSLHEIPQELGTLK-KLTHLSLGRNAFKEFP----RPACSITSLEILDLSD 421

Query: 191 NCLRELSPDIAHLASLKTLDLSNNQLTEIPAELADCPKLKEINFRGNRLRDKRLEKMVGG 250
           N + E+  DIA L SL+ L +  N ++   AEL    KL+  +F  N L D   E  V G
Sbjct: 422 NKITEIPSDIAQLLSLRELYMKKNAVSVFCAELCALQKLQMADFSNNGLLDLPEEVSVLG 601

Query: 251 C 251
           C
Sbjct: 602 C 604

 Score = 51.6 bits (122), Expect = 8e-07,   Method: Compositional matrix adjust.
 Identities = 35/106 (33%), Positives = 55/106 (51%)
 Frame = +2

Query: 132 QLQSLNLSGNRLRELPADLARCAPRLQSLNLTGNRLDAFPPELFRPGALPLLSELAAADN 191
           ++  L LS N    +P  +      L++L L GN L   P EL   G L  L+ L+   N
Sbjct: 188 KITRLILSDNNFTSVPVAIGSLT-ELEALLLDGNSLHEIPQEL---GTLKKLTHLSLGRN 355

Query: 192 CLRELSPDIAHLASLKTLDLSNNQLTEIPAELADCPKLKEINFRGN 237
             +E       + SL+ LDLS+N++TEIP+++A    L+E+  + N
Sbjct: 356 AFKEFPRPACSITSLEILDLSDNKITEIPSDIAQLLSLRELYMKKN 493

 Score = 49.3 bits (116), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 35/102 (34%), Positives = 55/102 (53%)
 Frame = +2

Query: 133 LQSLNLSGNRLRELPADLARCAPRLQSLNLTGNRLDAFPPELFRPGALPLLSELAAADNC 192
           L+ L+LS N++ E+P+D+A+    L+ L +  N +  F  EL    AL  L     ++N 
Sbjct: 398 LEILDLSDNKITEIPSDIAQLL-SLRELYMKKNAVSVFCAEL---CALQKLQMADFSNNG 565

Query: 193 LRELSPDIAHLASLKTLDLSNNQLTEIPAELADCPKLKEINF 234
           L +L  +++ L  L+ LDLSNNQ  E P      P L ++ F
Sbjct: 566 LLDLPEEVSVLGCLQELDLSNNQFFEFPKTACSIPHLHKLVF 691

 Score = 38.9 bits (89), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 31/110 (28%), Positives = 50/110 (45%)
 Frame = +2

Query: 132 QLQSLNLSGNRLRELPADLARCAPRLQSLNLTGNRLDAFPPELFRPGALPLLSELAAADN 191
           +L+ +    N+L  +P  +  C+  L+ L+L  N L+  P E      L  ++ L  +DN
Sbjct: 50  ELKEVYCGSNQLTLIPESICWCS-NLEILSLHKNHLERLPVEF---ANLRKITRLILSDN 217

Query: 192 CLRELSPDIAHLASLKTLDLSNNQLTEIPAELADCPKLKEINFRGNRLRD 241
               +   I  L  L+ L L  N L EIP EL    KL  ++   N  ++
Sbjct: 218 NFTSVPVAIGSLTELEALLLDGNSLHEIPQELGTLKKLTHLSLGRNAFKE 367

 Score = 36.6 bits (83), Expect = 0.025,   Method: Compositional matrix adjust.
 Identities = 20/50 (40%), Positives = 27/50 (54%)
 Frame = +2

Query: 190 DNCLRELSPDIAHLASLKTLDLSNNQLTEIPAELADCPKLKEINFRGNRL 239
           +NCL  L  DIA L  LK +   +NQLT IP  +  C  L+ ++   N L
Sbjct: 5   NNCLTVLPEDIAELFELKEVYCGSNQLTLIPESICWCSNLEILSLHKNHL 154
>05532
          Length = 1607

 Score = 49.3 bits (116), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 28/68 (41%), Positives = 41/68 (60%)
 Frame = +3

Query: 172 PELFRPGALPLLSELAAADNCLRELSPDIAHLASLKTLDLSNNQLTEIPAELADCPKLKE 231
           PELFR      L+ L   DN L  +SP ++ L  L  LDLS+NQL+ +P+E+ D  +L+E
Sbjct: 159 PELFR---FQHLTCLYLNDNRLDHISPHVSQLHHLVCLDLSSNQLSSLPSEIGDLTELRE 329

Query: 232 INFRGNRL 239
           +    N+L
Sbjct: 330 LLLYNNQL 353

 Score = 48.5 bits (114), Expect = 7e-06,   Method: Compositional matrix adjust.
 Identities = 40/128 (31%), Positives = 59/128 (46%)
 Frame = +3

Query: 133 LQSLNLSGNRLRELPADLARCAPRLQSLNLTGNRLDAFPPELFRPGALPLLSELAAADNC 192
             ++ +SG  +R +  +L R    L  L L  NRLD   P +     L  L  L  + N 
Sbjct: 117 WHTITISG-LVRNISPELFRFQ-HLTCLYLNDNRLDHISPHV---SQLHHLVCLDLSSNQ 281

Query: 193 LRELSPDIAHLASLKTLDLSNNQLTEIPAELADCPKLKEINFRGNRLRDKRLEKMVGGCQ 252
           L  L  +I  L  L+ L L NNQLT +P EL    +L+ ++ +GN L    +    G   
Sbjct: 282 LSSLPSEIGDLTELRELLLYNNQLTSLPFELGRLFQLQNLDIKGNPLSQDYMHFYQGMNG 461

Query: 253 TKSILEYL 260
           T  +L +L
Sbjct: 462 TNDLLSFL 485
>30747
          Length = 1168

 Score = 43.9 bits (102), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 36/105 (34%), Positives = 60/105 (57%)
 Frame = +3

Query: 133 LQSLNLSGNRLRELPADLARCAPRLQSLNLTGNRLDAFPPELFRPGALPLLSELAAADNC 192
           L+ L +SGN +++L  DL RC  +L  L+L+ NRL     ++     LP L  L  +DN 
Sbjct: 606 LEELFVSGNSIQKL-TDLHRCK-KLSELDLSRNRL----VDISGISGLPALQTLDMSDNR 767

Query: 193 LRELSPDIAHLASLKTLDLSNNQLTEIPAELADCPKLKEINFRGN 237
           L+ ++  +  L SL+TL+L+ NQ++E+    +  PKL+ +    N
Sbjct: 768 LKSVTS-LGKLKSLETLNLNGNQISELLGWGSCFPKLQILKLCDN 899

 Score = 33.9 bits (76), Expect = 0.17,   Method: Compositional matrix adjust.
 Identities = 40/139 (28%), Positives = 63/139 (45%), Gaps = 1/139 (0%)
 Frame = +3

Query: 103 LRVLDLSGNXXXXXXXXXXXXXXXXXXXXQLQSLNLSGNRLRELPADLARCAPRLQSLNL 162
           LRVLD+SGN                     L+ L L  N++ ++          L SL L
Sbjct: 267 LRVLDVSGNYITKIQHLEFTQ--------DLRDLKLYDNKVSQVQG--LESLKELCSLQL 416

Query: 163 TGNRLDAFPPELFRPGALPLLSELAAADNCLREL-SPDIAHLASLKTLDLSNNQLTEIPA 221
             N++++    L    AL  L  L    N L +L + ++    ++ TLDLSNN +T + A
Sbjct: 417 QYNQIESLGKGL---NALKKLKCLRLDSNRLTKLDTNELLSCVNISTLDLSNNHITNLSA 587

Query: 222 ELADCPKLKEINFRGNRLR 240
            L+  P L+E+   GN ++
Sbjct: 588 -LSYLPNLEELFVSGNSIQ 641
>19531
          Length = 415

 Score = 39.7 bits (91), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 32/102 (31%), Positives = 49/102 (48%)
 Frame = -2

Query: 133 LQSLNLSGNRLRELPADLARCAPRLQSLNLTGNRLDAFPPELFRPGALPLLSELAAADNC 192
           L  L++  N L+ LP  L      LQ LN++ N+L   P  +   G L  L  + A  N 
Sbjct: 297 LTVLDVHDNHLQSLPNALGEL-ENLQKLNISHNQLVELPSCI---GRLSNLVSVHAEHNK 130

Query: 193 LRELSPDIAHLASLKTLDLSNNQLTEIPAELADCPKLKEINF 234
           L  + PD+     L+ LD+SNN L E+P  +    ++  +N 
Sbjct: 129 LTLICPDLVDCRKLEELDVSNNDLAELPKYIGLLSRMFRLNV 4

 Score = 35.8 bits (81), Expect = 0.043,   Method: Compositional matrix adjust.
 Identities = 28/93 (30%), Positives = 44/93 (47%), Gaps = 23/93 (24%)
 Frame = -2

Query: 180 LPLLSELAAADNCLRELSPDIAHLASLKTLDLSNNQLTEIPA------------------ 221
           LP L+ L   DN L+ L   +  L +L+ L++S+NQL E+P+                  
Sbjct: 306 LPALTVLDVHDNHLQSLPNALGELENLQKLNISHNQLVELPSCIGRLSNLVSVHAEHNKL 127

Query: 222 -----ELADCPKLKEINFRGNRLRDKRLEKMVG 249
                +L DC KL+E++   N L +  L K +G
Sbjct: 126 TLICPDLVDCRKLEELDVSNNDLAE--LPKYIG 34
>36727
          Length = 193

 Score = 33.1 bits (74), Expect = 0.32,   Method: Compositional matrix adjust.
 Identities = 24/59 (40%), Positives = 30/59 (50%), Gaps = 1/59 (1%)
 Frame = +3

Query: 183 LSELAAADNCLRELSPDIAHLASLKTLDLSNNQLTEIPAE-LADCPKLKEINFRGNRLR 240
           L  L    N L +L P I H   L   DLS+N +TEI  E L   P+L ++N   N LR
Sbjct: 3   LMSLHFRSNALTKL-PQIPHGEGLHQFDLSSNVITEIQEEDLLHFPELGQLNLARNSLR 176
>20480
          Length = 638

 Score = 30.8 bits (68), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 14/47 (29%), Positives = 28/47 (59%)
 Frame = -1

Query: 193 LRELSPDIAHLASLKTLDLSNNQLTEIPAELADCPKLKEINFRGNRL 239
           L+ ++  +  L  L+ LDLSNN +  + +EL+    L+++   GN++
Sbjct: 467 LQAVNRSVFRLPKLQILDLSNNDIEAVSSELSGLQTLRQLILNGNKM 327

 Score = 29.3 bits (64), Expect = 4.7,   Method: Compositional matrix adjust.
 Identities = 17/44 (38%), Positives = 24/44 (54%), Gaps = 1/44 (2%)
 Frame = -2

Query: 198 PD-IAHLASLKTLDLSNNQLTEIPAELADCPKLKEINFRGNRLR 240
           PD +  L  L  L LSNN++TEIP  ++    L+ +   GN  R
Sbjct: 592 PDPVFDLEQLVCLSLSNNKITEIPDAISHLDNLEVLVLSGNSYR 461
>14078
          Length = 1045

 Score = 30.0 bits (66), Expect = 3.0,   Method: Compositional matrix adjust.
 Identities = 19/63 (30%), Positives = 30/63 (47%)
 Frame = -1

Query: 175 FRPGALPLLSELAAADNCLRELSPDIAHLASLKTLDLSNNQLTEIPAELADCPKLKEINF 234
           +R   L    +L  A N ++ +   +   A L TL L +NQL  +     D  +L+ +N 
Sbjct: 385 YRWYLLTQHQKLVLAANVIKRIEG-LGRCAGLTTLHLRDNQLESLDGFTDDLKELQYVNL 209

Query: 235 RGN 237
           RGN
Sbjct: 208 RGN 200
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6754240|ref|NP_034601.1| hippocalcin [Mus musculus]
         (193 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

26019                                                                  60   5e-10
14594                                                                  49   1e-06
07198                                                                  44   6e-05
07678                                                                  43   7e-05
18571                                                                  42   1e-04
05230                                                                  40   5e-04
05237                                                                  38   0.002
00167                                                                  37   0.004
15966                                                                  37   0.004
01019                                                                  36   0.008
01773                                                                  36   0.010
33397                                                                  33   0.059
35074                                                                  30   0.42 
38338                                                                  30   0.46 
17484                                                                  30   0.87 
08380                                                                  29   0.94 
01401                                                                  28   2.4  
26849                                                                  28   2.7  
28870                                                                  27   5.2  
09380                                                                  27   5.3  
32088                                                                  26   8.5  
>26019
          Length = 1561

 Score = 60.5 bits (145), Expect = 5e-10,   Method: Compositional matrix adjust.
 Identities = 32/90 (35%), Positives = 54/90 (60%), Gaps = 1/90 (1%)
 Frame = +2

Query: 40  TGILNVDEFKKIYANFFPYGDASKFAEHVFRTFDTNSDGTIDFREFIIALSVTS-RGRLE 98
           +G L++DEF  +     P    +   + V   FDT+ +G +DF+EFI  +S  S +G  E
Sbjct: 140 SGSLSIDEFMSL-----PELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGISQFSVKGDKE 304

Query: 99  QKLMWAFSMYDLDGNGYISREEMLEIVQAI 128
            KL +AF +YD+D +GYIS  E+ ++++ +
Sbjct: 305 SKLRFAFKIYDMDKDGYISNGELFQVLKMM 394
>14594
          Length = 1014

 Score = 48.9 bits (115), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 28/99 (28%), Positives = 53/99 (53%), Gaps = 1/99 (1%)
 Frame = +3

Query: 73  DTNSDGTIDFREFIIALSVTSRGR-LEQKLMWAFSMYDLDGNGYISREEMLEIVQAIYKM 131
           D + +GTIDF EF+  ++   +    E++L  AF ++D DGNGYIS  E+  ++  +   
Sbjct: 579 DADGNGTIDFEEFLHMMARKMKDTDCEEELREAFRVFDKDGNGYISAAELRHVMTNL--- 749

Query: 132 VSSVMKMPEDESTPEKRTEKIFRQMDTNNDGKLSLEEFI 170
                     E   ++  +++ ++ D + DG ++ EEF+
Sbjct: 750 ---------GEKLTDEEVDEMIKEADLDGDGMVNYEEFV 839

 Score = 31.6 bits (70), Expect = 0.20,   Method: Compositional matrix adjust.
 Identities = 25/105 (23%), Positives = 46/105 (43%)
 Frame = +3

Query: 23  SELELQEWYKGFLKDCPTGILNVDEFKKIYANFFPYGDASKFAEHVFRTFDTNSDGTIDF 82
           +E ELQ+       D   G ++ +EF  + A      D  +     FR FD + +G I  
Sbjct: 543 TENELQDMINEVDAD-GNGTIDFEEFLHMMARKMKDTDCEEELREAFRVFDKDGNGYISA 719

Query: 83  REFIIALSVTSRGRLEQKLMWAFSMYDLDGNGYISREEMLEIVQA 127
            E    ++       ++++       DLDG+G ++ EE + ++ A
Sbjct: 720 AELRHVMTNLGEKLTDEEVDEMIKEADLDGDGMVNYEEFVTMMTA 854
>07198
          Length = 1675

 Score = 43.5 bits (101), Expect = 6e-05,   Method: Compositional matrix adjust.
 Identities = 40/134 (29%), Positives = 57/134 (42%), Gaps = 1/134 (0%)
 Frame = -3

Query: 41  GILNVDEFKKIYANFFPYGDASKFAEHVFRTFDTNSDGTIDFREFII-ALSVTSRGRLEQ 99
           G LN  E+   +A F P        E   R  D N DGTI   EF+    +  +R   E+
Sbjct: 437 GSLNSKEY---FAFFMPNSFPQLELERFMRQSDKNKDGTISMEEFMPEGATGDTRTSSEE 267

Query: 100 KLMWAFSMYDLDGNGYISREEMLEIVQAIYKMVSSVMKMPEDESTPEKRTEKIFRQMDTN 159
               +F  YD D +G +S EE +E +             P  +   +   E +F   D N
Sbjct: 266 ----SFKNYDKDKDGSLSLEEAMEWIN------------PSSDEHADVEVEHLFTIGDVN 135

Query: 160 NDGKLSLEEFIRGA 173
           +DGKLS +E +  A
Sbjct: 134 HDGKLSKDEILNKA 93
>07678
          Length = 958

 Score = 43.1 bits (100), Expect = 7e-05,   Method: Compositional matrix adjust.
 Identities = 40/132 (30%), Positives = 61/132 (46%), Gaps = 5/132 (3%)
 Frame = +1

Query: 43  LNVDEFKKIYANFFPYGDASKFAEHVFRTFDTNSDGTIDFREFIIALSVTSRGRLEQKLM 102
           L+  EFKK    F          + +F  FD +  GTIDF EF++ L        +  + 
Sbjct: 370 LDFKEFKKGITEFGLTQFEGDVIQEMFTCFDKDZSGTIDFDEFLVKLRPPMSQMRKDLIQ 549

Query: 103 WAFSMYDLDGNGYISREEMLEIVQAIYKMVSSVMKMPE--DESTPEKRTEKIF-RQMDTN 159
            AF   D  G+G ++ E++        K V +V K P+  +    E+R  +IF    D+ 
Sbjct: 550 RAFQKLDKTGDGVVTVEDL--------KGVYNVTKHPKYLNGEWTEERILRIFLDSFDSP 705

Query: 160 N--DGKLSLEEF 169
           N  DGK++ EEF
Sbjct: 706 NDKDGKITKEEF 741
>18571
          Length = 821

 Score = 42.4 bits (98), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 21/38 (55%), Positives = 23/38 (60%)
 Frame = -2

Query: 153 FRQMDTNNDGKLSLEEFIRGAKSDPSIVRLLQCDPSSA 190
           FRQMD N DGKLSLEEFI G  + P +       PS A
Sbjct: 811 FRQMDKNLDGKLSLEEFIEGP*TIPPLFDFCSVTPSRA 698
>05230
          Length = 843

 Score = 40.4 bits (93), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 26/86 (30%), Positives = 47/86 (54%), Gaps = 3/86 (3%)
 Frame = -2

Query: 89  LSVTSRGRLEQKL-MW--AFSMYDLDGNGYISREEMLEIVQAIYKMVSSVMKMPEDESTP 145
           +S+ S   ++ K  MW   F+ +D DG+G+ SRE+++E ++ I   +           TP
Sbjct: 680 ISIMSDASVDMKTNMWRKLFAQFDTDGSGWASREDVIEGLENIGITI-----------TP 534

Query: 146 EKRTEKIFRQMDTNNDGKLSLEEFIR 171
           + R +   + MD N DGK++  +F+R
Sbjct: 533 DLRAK--IKAMDGNKDGKINYADFLR 462
>05237
          Length = 472

 Score = 38.1 bits (87), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 19/74 (25%), Positives = 40/74 (54%)
 Frame = +3

Query: 98  EQKLMWAFSMYDLDGNGYISREEMLEIVQAIYKMVSSVMKMPEDESTPEKRTEKIFRQMD 157
           + +L  AF ++D DGNG+IS  E+  ++  +             E   ++  +++ R+ D
Sbjct: 24  DDELREAFRVFDKDGNGFISASELRHVMTNLG------------EKLTDEEVDEMIREAD 167

Query: 158 TNNDGKLSLEEFIR 171
            + DG+++ EEF++
Sbjct: 168 IDGDGQVNYEEFVK 209
>00167
          Length = 2176

 Score = 37.4 bits (85), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 28/105 (26%), Positives = 52/105 (49%), Gaps = 2/105 (1%)
 Frame = +3

Query: 68  VFRTFDTNSDGTIDFREFIIALSVTSRGRLEQKLMWAFSMYDLDGNGYISREEMLEIVQA 127
           VFR FD +  GT+DF EF++AL         + +  AF+  D  G+G I+ ++++     
Sbjct: 855 VFRRFDKDGTGTLDFEEFLLALRPKMNEFRRKLVKKAFAKMDKTGDGIITADDLVGTYD- 1031

Query: 128 IYKMVSSVMKMPEDESTPEKRTEKIFRQ--MDTNNDGKLSLEEFI 170
               V S  +    E T ++  ++      +  N+DG +++ E+I
Sbjct: 1032----VRSHPRYQNGELTKKQVYQEFLDNFVVGDNDDGVITMAEWI 1154

 Score = 29.3 bits (64), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 13/22 (59%), Positives = 16/22 (72%)
 Frame = +3

Query: 153 FRQMDTNNDGKLSLEEFIRGAK 174
           FR MD N D KLS++EFI G +
Sbjct: 747 FRIMDDNRDRKLSVDEFIVGCR 812
>15966
          Length = 362

 Score = 37.4 bits (85), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 32/112 (28%), Positives = 46/112 (41%), Gaps = 1/112 (0%)
 Frame = +2

Query: 60  DASKFAEHV-FRTFDTNSDGTIDFREFIIALSVTSRGRLEQKLMWAFSMYDLDGNGYISR 118
           D S+ + H  F    +  D  I F EF   L         QKL   F   D  G+GY+ R
Sbjct: 20  DESRRSRHARFFVVPSCGDKRITFEEFCKGLDQIVM--FVQKLAELFKAKDKSGDGYLDR 193

Query: 119 EEMLEIVQAIYKMVSSVMKMPEDESTPEKRTEKIFRQMDTNNDGKLSLEEFI 170
           +E+  ++        S  K   D+ +       I +  D NND K+  EEF+
Sbjct: 194 DELKALLD------ESGQKFTADDVSA------ILKSADKNNDNKICFEEFV 313
>01019
          Length = 1705

 Score = 36.2 bits (82), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 17/68 (25%), Positives = 35/68 (51%)
 Frame = +1

Query: 103 WAFSMYDLDGNGYISREEMLEIVQAIYKMVSSVMKMPEDESTPEKRTEKIFRQMDTNNDG 162
           W   ++D DGNG+IS  E+  ++  +             E   ++  +++ R+ D + DG
Sbjct: 31  WPLLVFDKDGNGFISAAELRHVMTNL------------GEKLTDEEVDEMIREADIDGDG 174

Query: 163 KLSLEEFI 170
           +++ EEF+
Sbjct: 175 QVNYEEFV 198
>01773
          Length = 1950

 Score = 35.8 bits (81), Expect = 0.010,   Method: Compositional matrix adjust.
 Identities = 22/72 (30%), Positives = 33/72 (45%)
 Frame = +1

Query: 99  QKLMWAFSMYDLDGNGYISREEMLEIVQAIYKMVSSVMKMPEDESTPEKRTEKIFRQMDT 158
           QKL   F   D  G+GY+ R+E+  ++        S  K   D+ +       I +  D 
Sbjct: 367 QKLAELFKAKDKSGDGYLDRDELKALLD------ESGQKFTADDVSA------ILKSADK 510

Query: 159 NNDGKLSLEEFI 170
           NND K+  EEF+
Sbjct: 511 NNDNKICFEEFV 546
>33397
          Length = 1723

 Score = 33.5 bits (75), Expect = 0.059,   Method: Compositional matrix adjust.
 Identities = 16/29 (55%), Positives = 18/29 (62%)
 Frame = +3

Query: 143 STPEKRTEKIFRQMDTNNDGKLSLEEFIR 171
           STP +  E  FR  D N DG+L LEEF R
Sbjct: 180 STPPRNFEIAFRMFDINGDGELDLEEFNR 266

 Score = 28.9 bits (63), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 19/67 (28%), Positives = 32/67 (47%)
 Frame = +3

Query: 78  GTIDFREFIIALSVTSRGRLEQKLMWAFSMYDLDGNGYISREEMLEIVQAIYKMVSSVMK 137
           G I F ++I  L+V S     +    AF M+D++G+G +  EE    VQ + +  + V  
Sbjct: 135 GLISFSDYIFLLTVLSTP--PRNFEIAFRMFDINGDGELDLEE-FNRVQGVIRNQTHVGA 305

Query: 138 MPEDEST 144
              D + 
Sbjct: 306 RHRDHAV 326

 Score = 26.2 bits (56), Expect = 8.5,   Method: Compositional matrix adjust.
 Identities = 19/67 (28%), Positives = 30/67 (44%)
 Frame = +2

Query: 104 AFSMYDLDGNGYISREEMLEIVQAIYKMVSSVMKMPEDESTPEKRTEKIFRQMDTNNDGK 163
           A S Y L G         + I +  +  V+  + M +     E   + +F   D NNDG+
Sbjct: 671 ALSFYHLAG---------VSIDRETFHHVAKTVAMAD---LTEHVIDVVFTLFDENNDGE 814

Query: 164 LSLEEFI 170
           LS +EF+
Sbjct: 815 LSNKEFV 835
>35074
          Length = 654

 Score = 30.4 bits (67), Expect = 0.42,   Method: Compositional matrix adjust.
 Identities = 14/36 (38%), Positives = 21/36 (58%)
 Frame = +2

Query: 147 KRTEKIFRQMDTNNDGKLSLEEFIRGAKSDPSIVRL 182
            R++ I   M  N  G + L  FIR A++DP++V L
Sbjct: 59  ARSQNIPASMVNNQFGMVGLLTFIRAAETDPNLVTL 166
>38338
          Length = 463

 Score = 30.4 bits (67), Expect = 0.46,   Method: Compositional matrix adjust.
 Identities = 16/49 (32%), Positives = 22/49 (44%)
 Frame = -2

Query: 68  VFRTFDTNSDGTIDFREFIIALSVTSRGRLEQKLMWAFSMYDLDGNGYI 116
            F  FD + DGTI  +E    +    +   E +L    +  D DGNG I
Sbjct: 153 AFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTI 7
>17484
          Length = 471

 Score = 29.6 bits (65), Expect = 0.87,   Method: Compositional matrix adjust.
 Identities = 18/59 (30%), Positives = 27/59 (45%)
 Frame = -1

Query: 108 YDLDGNGYISREEMLEIVQAIYKMVSSVMKMPEDESTPEKRTEKIFRQMDTNNDGKLSL 166
           YD DGNG I+R E   +V+ +              S  EK  E++ +  DT+  G + L
Sbjct: 465 YDQDGNGKITRNEFRSVVRML------------GHSLSEKELEEMMQAADTDASGAIEL 325
>08380
          Length = 1236

 Score = 29.3 bits (64), Expect = 0.94,   Method: Compositional matrix adjust.
 Identities = 30/136 (22%), Positives = 56/136 (41%), Gaps = 24/136 (17%)
 Frame = -1

Query: 58  YGDASKFAEHVFRTFDTNSDGTIDFREFIIAL--------SVTSRGRL------------ 97
           + +A++  E +F+  D +++G + ++E+ +           V SR  +            
Sbjct: 783 FSEATQENEEIFKHLDPDNNGKVHWKEYYVHFLLAKGYKQDVASRHVVDYDZIQLDPDAK 604

Query: 98  EQKLMWAFSMYDLDG---NGYISREEMLEIVQAIYKMVSSVMKMPED-ESTPEKRTEKIF 153
           E+ + + F   D DG   +  ++REE +              + PE  E T       I 
Sbjct: 603 EEIIRYKFRWSDADGEPMDNELTREEFMSF------------RHPEQSEKTLNNMVNGIL 460

Query: 154 RQMDTNNDGKLSLEEF 169
             +DTN DG ++ EEF
Sbjct: 459 GGIDTNGDGVVTEEEF 412
>01401
          Length = 1454

 Score = 28.1 bits (61), Expect = 2.4,   Method: Compositional matrix adjust.
 Identities = 14/45 (31%), Positives = 23/45 (51%)
 Frame = +1

Query: 135 VMKMPEDESTPEKRTEKIFRQMDTNNDGKLSLEEFIRGAKSDPSI 179
           VM M E  +        +FRQ+D +N G L+ EE +   +S+  +
Sbjct: 238 VMGMQEAATV----MAHVFRQLDKDNSGSLTREEIMAAVQSEGEL 360
>26849
          Length = 649

 Score = 27.7 bits (60), Expect = 2.7,   Method: Compositional matrix adjust.
 Identities = 17/53 (32%), Positives = 31/53 (58%), Gaps = 1/53 (1%)
 Frame = +2

Query: 42  ILNVDEFKK-IYANFFPYGDASKFAEHVFRTFDTNSDGTIDFREFIIALSVTS 93
           +L+++EFKK I        +A    E +F  FD + +GTI+  EF++ ++ T+
Sbjct: 215 VLSLEEFKKGILDMHIDINEAD--IEDMFYRFDNDGNGTINMTEFLLKVASTN 367
>28870
          Length = 846

 Score = 26.9 bits (58), Expect = 5.2,   Method: Compositional matrix adjust.
 Identities = 17/51 (33%), Positives = 24/51 (47%), Gaps = 2/51 (3%)
 Frame = -3

Query: 141 DESTPEKRTEKIFRQM--DTNNDGKLSLEEFIRGAKSDPSIVRLLQCDPSS 189
           D S   +R   +F  +  DTN  G+ S  E    +  D   + +L CDPSS
Sbjct: 799 DTSLDSRRCSSVFSDVKSDTNGKGRQSGWEDGESSDEDDGGLGMLDCDPSS 647
>09380
          Length = 1342

 Score = 26.9 bits (58), Expect = 5.3,   Method: Compositional matrix adjust.
 Identities = 13/38 (34%), Positives = 19/38 (50%), Gaps = 5/38 (13%)
 Frame = +2

Query: 34 FLKDCPTGILNVDEFKKIYANFFP-----YGDASKFAE 66
          F +DC T  L+   F +I  NFF      + D S+F+ 
Sbjct: 44 FFQDC*TFFLDCSRFSRIVTNFFKDC*KFFQDCSRFSR 157
>32088
          Length = 1928

 Score = 26.2 bits (56), Expect = 8.5,   Method: Compositional matrix adjust.
 Identities = 18/70 (25%), Positives = 30/70 (42%)
 Frame = +1

Query: 100  KLMWAFSMYDLDGNGYISREEMLEIVQAIYKMVSSVMKMPEDESTPEKRTEKIFRQMDTN 159
            +L   F   D D NG+IS  E+    +A+   +            P      I  + D +
Sbjct: 946  ELRSVFDSIDDDNNGHISXGELDSAFRAVGLNI------------PGYELRTIMSKYDAS 1089

Query: 160  NDGKLSLEEF 169
             DG+L+++EF
Sbjct: 1090 GDGRLNMDEF 1119
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|110625776|ref|NP_081688.2| tetratricopeptide repeat
domain 9C [Mus musculus]
         (171 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

03857                                                                  60   6e-10
00888                                                                  55   1e-08
13560                                                                  38   0.003
26568                                                                  26   0.095
30337                                                                  29   0.77 
33087                                                                  29   0.77 
22027                                                                  29   0.85 
32109                                                                  29   1.0  
35348                                                                  28   2.5  
23484                                                                  27   2.8  
22083                                                                  27   3.0  
15572                                                                  27   3.7  
14910                                                                  27   4.5  
>03857
          Length = 1696

 Score = 59.7 bits (143), Expect = 6e-10,   Method: Compositional matrix adjust.
 Identities = 46/161 (28%), Positives = 71/161 (44%), Gaps = 2/161 (1%)
 Frame = +1

Query: 12  KEEGNQRYREGKYRDAVSRYHRAL--LQXXXXXXXXXXXXXXXXXXXXALTPEQENILHT 69
           K+ GN  ++ GK+  A  +Y +AL  LQ                        +Q+ +   
Sbjct: 475 KQAGNTLFKAGKFGPANRKYKKALRYLQKLDEEQKMSED-------------QQKAMEKE 615

Query: 70  IQTHCYNNLAACLLQMEPVNYERVREYSQKVLERQPDNAKALYRAGVAFFHLQDYDRARH 129
           +      N AAC L++    Y    EY Q+VLE  PDN+KA YR G A    +DY+ A  
Sbjct: 616 LHIPVSLNAAACCLKLN--KYNEALEYCQEVLEADPDNSKAQYRQGQAHAGNKDYETALA 789

Query: 130 HLLAAVNRQPKDANVRRYLQLTQSELSSYHRKEKQLYLGMF 170
               A+   P D  ++  +Q  +  +    ++EKQ+Y  MF
Sbjct: 790 SFQKALAANPDDKGIKLEIQKVKRTVEEEKKREKQMYSRMF 912
>00888
          Length = 970

 Score = 55.1 bits (131), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 40/168 (23%), Positives = 77/168 (45%), Gaps = 1/168 (0%)
 Frame = -3

Query: 4   RLQEAQVYKEEGNQRYREGKYRDAVSRYHRALLQXXXXXXXXXXXXXXXXXXXXALTPEQ 63
           +++++++ KE+G   +++GKY+ A++ Y + +                       L+  +
Sbjct: 752 KIEQSKIIKEKGTAAFKKGKYQRALTNYEKIV--------------SFLEHESTGLSDSE 615

Query: 64  ENILHTIQTHCYNNLAACLLQMEPVNYERVREYSQKVLERQPDNAKALYRAGVAFFHLQD 123
            +  H +    + N+A C  Q++ ++Y +  E   KVL    +N KAL+R G A     D
Sbjct: 614 LSDKHQLMVAAFLNIAMC--QLKLLDYRQAEETCNKVLAMSTNNVKALFRRGQARLECAD 441

Query: 124 YDRARHHLLAAVNRQPKD-ANVRRYLQLTQSELSSYHRKEKQLYLGMF 170
           Y  A       +  +P + A   +++   Q + + Y  KEK LY  MF
Sbjct: 440 YTEAASDFSKVLELEPGNKAAKNQHIVCLQKQKADYA-KEKALYTNMF 300
>13560
          Length = 978

 Score = 37.7 bits (86), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 38/165 (23%), Positives = 61/165 (36%)
 Frame = +1

Query: 6   QEAQVYKEEGNQRYREGKYRDAVSRYHRALLQXXXXXXXXXXXXXXXXXXXXALTPEQEN 65
             A V+KE+G Q ++ G    A S +  A+                       L  +   
Sbjct: 184 SSASVHKEKGAQYFKTGNIFAAFSHFRTAIRLLLSVLPYSFSDDEVASTSHLQLLCQ--- 354

Query: 66  ILHTIQTHCYNNLAACLLQMEPVNYERVREYSQKVLERQPDNAKALYRAGVAFFHLQDYD 125
                   CY NLAAC  Q++  +++ V       L   P N KALYR   A  +L +  
Sbjct: 355 --------CYLNLAAC--QIKSGHHKHVITNCTHALNLDPANVKALYRRASANVNLGNLL 504

Query: 126 RARHHLLAAVNRQPKDANVRRYLQLTQSELSSYHRKEKQLYLGMF 170
            A   L   + ++P +  +   +Q   + L+    +  Q    MF
Sbjct: 505 HAHEDLETGLQKEPNNRALLDLMQNVNARLAPSQSQMAQGLSKMF 639
>26568
          Length = 398

 Score = 25.8 bits (55), Expect(2) = 0.095,   Method: Compositional matrix adjust.
 Identities = 21/84 (25%), Positives = 36/84 (42%)
 Frame = +1

Query: 2   EKRLQEAQVYKEEGNQRYREGKYRDAVSRYHRALLQXXXXXXXXXXXXXXXXXXXXALTP 61
           E RL   +  +E GNQ + + +Y  +++ Y  AL                        T 
Sbjct: 88  EDRLVFGEQKRERGNQLFSQEEYHSSINSYTLAL-----------KYLDASFGGLTGNTS 234

Query: 62  EQENILHTIQTHCYNNLAACLLQM 85
             +NI+ + +  CYNN+AA  L++
Sbjct: 235 VLQNIVDS-KLKCYNNMAAAQLKI 303

 Score = 25.4 bits (54), Expect(2) = 0.095,   Method: Compositional matrix adjust.
 Identities = 10/15 (66%), Positives = 13/15 (86%)
 Frame = +3

Query: 99  KVLERQPDNAKALYR 113
           +VL+ QP+N KALYR
Sbjct: 336 RVLKSQPENVKALYR 380
>30337
          Length = 493

 Score = 29.3 bits (64), Expect = 0.77,   Method: Compositional matrix adjust.
 Identities = 28/123 (22%), Positives = 46/123 (37%)
 Frame = -1

Query: 12  KEEGNQRYREGKYRDAVSRYHRALLQXXXXXXXXXXXXXXXXXXXXALTPEQENILHTIQ 71
           K +GN+ +   KY DA+  Y +A+++                       P          
Sbjct: 319 KNQGNKLFAARKYEDAIHCYTKAIMK----------------------NPNTATY----- 221

Query: 72  THCYNNLAACLLQMEPVNYERVREYSQKVLERQPDNAKALYRAGVAFFHLQDYDRARHHL 131
              + N A C +++   N+E   +  Q+ LE   +  K  +  G A   L  YD A  HL
Sbjct: 220 ---FTNRALCYIKLR--NWELASQDCQRALELDRNLVKGHFFLGQALVELAMYDEAITHL 56

Query: 132 LAA 134
           + A
Sbjct: 55  MKA 47
>33087
          Length = 764

 Score = 29.3 bits (64), Expect = 0.77,   Method: Compositional matrix adjust.
 Identities = 12/28 (42%), Positives = 15/28 (53%)
 Frame = -2

Query: 116 VAFFHLQDYDRARHHLLAAVNRQPKDAN 143
           V  F+   +  A HH+L   NRQPK  N
Sbjct: 628 VLLFYFNVFXTAEHHILDG*NRQPKGGN 545
>22027
          Length = 692

 Score = 29.3 bits (64), Expect = 0.85,   Method: Compositional matrix adjust.
 Identities = 11/33 (33%), Positives = 22/33 (66%)
 Frame = -3

Query: 3   KRLQEAQVYKEEGNQRYREGKYRDAVSRYHRAL 35
           K +++A+  +  GN+ ++ GKY  A+S Y+ A+
Sbjct: 291 KSVEQAEALRTTGNEHFKCGKYDKALSCYNNAV 193
>32109
          Length = 576

 Score = 28.9 bits (63), Expect = 1.0,   Method: Compositional matrix adjust.
 Identities = 13/33 (39%), Positives = 19/33 (57%)
 Frame = +2

Query: 96  YSQKVLERQPDNAKALYRAGVAFFHLQDYDRAR 128
           Y  K L  QP+N KALY    A   + ++++AR
Sbjct: 8   YCHKALALQPNNVKALYHKAQALHFMSEFEQAR 106
>35348
          Length = 627

 Score = 27.7 bits (60), Expect = 2.5,   Method: Compositional matrix adjust.
 Identities = 13/35 (37%), Positives = 20/35 (57%)
 Frame = -2

Query: 1   MEKRLQEAQVYKEEGNQRYREGKYRDAVSRYHRAL 35
           ++KRL EA   K  GN  ++ G+Y +A+  Y   L
Sbjct: 605 LQKRLAEAVKVKVRGNDTFKSGQYAEALELYSEGL 501
>23484
          Length = 1647

 Score = 27.3 bits (59), Expect = 2.8,   Method: Compositional matrix adjust.
 Identities = 12/34 (35%), Positives = 19/34 (55%)
 Frame = +1

Query: 2   EKRLQEAQVYKEEGNQRYREGKYRDAVSRYHRAL 35
           E  +  A+ Y+EEGN  +++  YR AV  Y   +
Sbjct: 481 EDPVARAESYREEGNDLFKKKDYRLAVDNYXEGI 582
>22083
          Length = 500

 Score = 27.3 bits (59), Expect = 3.0,   Method: Compositional matrix adjust.
 Identities = 11/34 (32%), Positives = 20/34 (58%)
 Frame = -1

Query: 132 LAAVNRQPKDANVRRYLQLTQSELSSYHRKEKQL 165
           +   N  P+D   +RYL ++QSE+   +RK  ++
Sbjct: 437 MQGANAWPRDGIRKRYLHMSQSEVKRVYRKHIEI 336
>15572
          Length = 341

 Score = 26.9 bits (58), Expect = 3.7,   Method: Compositional matrix adjust.
 Identities = 12/38 (31%), Positives = 21/38 (55%)
 Frame = +3

Query: 74  CYNNLAACLLQMEPVNYERVREYSQKVLERQPDNAKAL 111
           C NN    +L  +P + +R  +Y+Q++ E    NAK +
Sbjct: 6   CTNNKTHYILNSDPASMDRGSDYAQRLNETSRSNAKQM 119
>14910
          Length = 1374

 Score = 26.9 bits (58), Expect = 4.5,   Method: Compositional matrix adjust.
 Identities = 11/27 (40%), Positives = 17/27 (62%)
 Frame = -3

Query: 141 DANVRRYLQLTQSELSSYHRKEKQLYL 167
           D  V RY+ LTQS+   +H  E ++Y+
Sbjct: 625 DPKVGRYVTLTQSKSEGFHLCEVRVYV 545
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|33468923|ref|NP_035413.1| retinitis pigmentosa 1 [Mus
musculus]
         (2095 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

14591                                                                  64   6e-10
18327                                                                  32   3.3  
14947                                                                  31   4.2  
>14591
          Length = 1324

 Score = 63.9 bits (154), Expect = 6e-10,   Method: Composition-based stats.
 Identities = 31/91 (34%), Positives = 55/91 (60%), Gaps = 4/91 (4%)
 Frame = +1

Query: 20  VPSPRHSNITHPVVAKRISFYKSGDPQFGGVRVVVNPRSFKTFDALLDSLSRKVP----L 75
           V   R+ ++  P   +++ F+ +GD  F G ++ + P  +  F  LL+ L+ K+P    L
Sbjct: 25  VTDDRYRDLRRP---RKVRFFVNGDRFFKGKKLHITPHRYYNFTDLLNDLTGKLPSSINL 195

Query: 76  PFGVRNISTPRGRHSITRLEELEDGKSYVCS 106
           P+GVR I TP G   ++ +E+L+DG++YVC+
Sbjct: 196 PYGVRQIFTPVGGRRVSDIEDLQDGETYVCA 288
>18327
          Length = 448

 Score = 31.6 bits (70), Expect = 3.3,   Method: Composition-based stats.
 Identities = 12/33 (36%), Positives = 20/33 (60%)
 Frame = +2

Query: 1170 NLMESTKTCSGSSGREQDMLPVNCTASSLHSVD 1202
            N ++ ++  S +  R  D+ P +CT  +LHSVD
Sbjct: 245  NTLKPSRCASDTGTRPYDITPTSCTMRTLHSVD 343
>14947
          Length = 1158

 Score = 31.2 bits (69), Expect = 4.2,   Method: Compositional matrix adjust.
 Identities = 24/81 (29%), Positives = 35/81 (43%), Gaps = 1/81 (1%)
 Frame = +2

Query: 1446 DTSIFNMNVRAEKKSTKETMQKQSEARMSSELINVSGRKIIEQERRNTAILETTARGQVT 1505
            D S+  + VR   +    T Q + +AR S       GRKII++ R+N       A   VT
Sbjct: 455  DESLKVVFVRDPFERLVSTYQSKFQARYSKYFHESFGRKIIQRYRKNATAQAKKAGNDVT 634

Query: 1506 PPSLA-FCYDSNKNTEKEISE 1525
                  F  DS   T+  ++E
Sbjct: 635  FGEFVRFVLDSEHETDGPLNE 697
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|10181110|ref|NP_065624.1| retinaldehyde binding
protein 1 [Mus musculus]
         (317 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

16531                                                                  61   7e-10
25484                                                                  40   0.001
26328                                                                  28   5.0  
>16531
          Length = 514

 Score = 60.8 bits (146), Expect = 7e-10,   Method: Compositional matrix adjust.
 Identities = 41/151 (27%), Positives = 68/151 (45%)
 Frame = -1

Query: 37  CSQLPRHTLQKAKDELNXXXXXXXXXXXXXXXLVQAQAASGEELALAVAERVQARDSAFL 96
           C+  P   L+KAK ELN                   +  +  E    V E     D  FL
Sbjct: 418 CTLRP-EVLEKAKKELNEDPNTR-----------HIEIKTLRERLEKVPEFKGRTDDGFL 275

Query: 97  LRFIRARKFDVGRAYELLKGYVNFRLQYPELFDSLSMEALRCTIEAGYPGVLSSRDKYGR 156
           LRF+R +KFD  RA++ +  Y   R Q+P+++++L  E +R  +E+G    L  R   G 
Sbjct: 274 LRFLRCKKFDQERAFKQVMTYYRMRKQFPDVYENLVPERVRGILESGVTAPLKDRAPDGS 95

Query: 157 VVMLFNIENWHCEEVTFDEILQAYCFILEKL 187
            ++ F +  W  ++ +  ++L      + KL
Sbjct: 94  RIIYFRLGRWDPDKGSLGDVLANNFLTISKL 2
>25484
          Length = 438

 Score = 39.7 bits (91), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 32/127 (25%), Positives = 59/127 (46%), Gaps = 12/127 (9%)
 Frame = -1

Query: 144 YPGVLSSRDKYGRVVML-----FNIENWHCEEVTFDEILQAYCFILEK------LLENEE 192
           +PG +  +DK G +V +      +I+      +   +I+++  FILE       LL  E+
Sbjct: 378 FPGGVCGQDKEGALVWVDPTGRVDIKG-ILRSMRKQDIVKSKVFILESIHRRCALLTREQ 202

Query: 193 TQ-INGFCIVENFKGFTMQQAAGLRPSDLKKMVDMLQDSFPARFKAIHFIHQPWYFTTTY 251
            + ++   IV + + F M+            +V M +D +P   K+   I+ P  F   Y
Sbjct: 201 NRLVDQIVIVFDMEYFGMKHLWKPGVDVFIDLVTMFEDHYPEMLKSCFVINAPKIFPIAY 22

Query: 252 NVVKPFL 258
           N+++PFL
Sbjct: 21  NIIRPFL 1
>26328
          Length = 442

 Score = 28.1 bits (61), Expect = 5.0,   Method: Compositional matrix adjust.
 Identities = 12/39 (30%), Positives = 22/39 (56%)
 Frame = +3

Query: 95  FLLRFIRARKFDVGRAYELLKGYVNFRLQYPELFDSLSM 133
           FLL F+R  KF + +A + +  Y + +   PE+F+   +
Sbjct: 126 FLLGFLRGSKFSLEKAKQKIDRYYSLQADIPEVFNKFRL 242
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|13591860|ref|NP_076253.1| toll interacting protein
[Mus musculus]
         (274 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

26949                                                                  60   7e-10
25953                                                                  46   6e-07
17245                                                                  40   8e-04
16275                                                                  29   1.8  
25399                                                                  29   2.3  
>26949
          Length = 449

 Score = 60.5 bits (145), Expect = 7e-10,   Method: Compositional matrix adjust.
 Identities = 26/42 (61%), Positives = 33/42 (78%)
 Frame = -3

Query: 232 EDLKAIQDMFPNMDREVIRSVLEAQRGNKDAAINSLLQMGEE 273
           EDL+ ++DMFPNM+ +VI+SV EA  GNKDA INSLL +  E
Sbjct: 183 EDLQLVKDMFPNMEDQVIKSVFEANNGNKDATINSLLSINSE 58

 Score = 49.7 bits (117), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 21/38 (55%), Positives = 28/38 (73%)
 Frame = -1

Query: 136 ITIPESLKQGQVEDEWYSLSGRQGDDKEGMINLVMSYT 173
           ITIP+S+  G   DEW+SLSGR GD  EG +N+V++ T
Sbjct: 446 ITIPQSVMNGDTADEWFSLSGRLGDGLEGSVNIVLTMT 333
>25953
          Length = 418

 Score = 46.2 bits (108), Expect(2) = 6e-07,   Method: Compositional matrix adjust.
 Identities = 21/33 (63%), Positives = 25/33 (75%)
 Frame = -1

Query: 241 FPNMDREVIRSVLEAQRGNKDAAINSLLQMGEE 273
            P+M++EVI SVL A  GNKDAAIN+LL M  E
Sbjct: 346 VPSMEKEVIHSVLVANHGNKDAAINALLSMSAE 248

 Score = 23.9 bits (50), Expect(2) = 6e-07,   Method: Compositional matrix adjust.
 Identities = 8/20 (40%), Positives = 12/20 (60%)
 Frame = -2

Query: 229 CNEEDLKAIQDMFPNMDREV 248
             E D++ +QDMFP   R +
Sbjct: 381 VTEADVQQVQDMFPAWRRRL 322
>17245
          Length = 1273

 Score = 40.4 bits (93), Expect = 8e-04,   Method: Compositional matrix adjust.
 Identities = 19/38 (50%), Positives = 23/38 (60%)
 Frame = -1

Query: 234 LKAIQDMFPNMDREVIRSVLEAQRGNKDAAINSLLQMG 271
           +     MFP+MDREVI +VL A  G  DA I+ LL M 
Sbjct: 784 MNDFHHMFPSMDREVIEAVLRANNGIVDATIDQLLTMS 671
>16275
          Length = 1553

 Score = 29.3 bits (64), Expect = 1.8,   Method: Compositional matrix adjust.
 Identities = 12/29 (41%), Positives = 19/29 (65%)
 Frame = -1

Query: 104 IQCTVPPGVDSFYLEIFDERAFSMDDRIA 132
           ++CT+PP +   YL I  + + SMDD I+
Sbjct: 422 LKCTMPPQISVKYLGIKIDSSLSMDDHIS 336
>25399
          Length = 1555

 Score = 28.9 bits (63), Expect = 2.3,   Method: Compositional matrix adjust.
 Identities = 16/74 (21%), Positives = 29/74 (39%)
 Frame = +1

Query: 74  DPYCRLRLGYAVYETPTAHNGAKNPRWNKVIQCTVPPGVDSFYLEIFDERAFSMDDRIAW 133
           D + R R  +        H     P+W ++  C+V  G           +  S  + + W
Sbjct: 880 DAFFRFRQTHETIYKS*KH--LSYPKWTELSNCSVIEG-----------KGISFSETVGW 1020

Query: 134 THITIPESLKQGQV 147
           T +++   LK GQ+
Sbjct: 1021TDMSMSGLLKNGQI 1062
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|33859524|ref|NP_034048.1| cyclic nucleotide gated
channel alpha 3 [Mus musculus]
         (631 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

19667                                                                  62   7e-10
24780                                                                  50   3e-06
08195                                                                  38   0.014
>19667
          Length = 442

 Score = 62.0 bits (149), Expect = 7e-10,   Method: Compositional matrix adjust.
 Identities = 39/118 (33%), Positives = 59/118 (50%), Gaps = 2/118 (1%)
 Frame = +3

Query: 426 DCEAGL-LVELVLKLRPTVFSPGDYICKKGDIGREMYIIKEGKLAVVADDGVTQFVVLSD 484
           DC  GL  V + L+     F PG+ +  KGD  R +Y +  G L V+ D+ V    +L  
Sbjct: 12  DCHPGLPFVPVALQTSRVFFGPGEVLIHKGDAIRNIYYVCSGSLEVLKDEQVV--AILGK 185

Query: 485 GSYFGEISILNIKGSKSGNRRTANIRSIGYSDLFCLSKDDLMEALTEYPD-AKRALEE 541
           G  FG     +IK     +    ++RS+ Y +L C++   L E L  YPD +++ LEE
Sbjct: 186 GDLFGS----DIKFEDPVSISGGDVRSLAYCELLCINTQGLAECLQPYPDFSEKFLEE 347
>24780
          Length = 572

 Score = 50.1 bits (118), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 20/34 (58%), Positives = 28/34 (82%)
 Frame = +3

Query: 503 NRRTANIRSIGYSDLFCLSKDDLMEALTEYPDAK 536
           NRRTA++RS GY+++F LSK D  EA+ EYP+A+
Sbjct: 3   NRRTADVRSSGYTNVFTLSKHDFEEAMNEYPEAQ 104
>08195
          Length = 2165

 Score = 37.7 bits (86), Expect = 0.014,   Method: Compositional matrix adjust.
 Identities = 23/91 (25%), Positives = 46/91 (50%), Gaps = 2/91 (2%)
 Frame = -3

Query: 406  KAEIAINVHLDTLKKVRIFQDCEAGLLVELVLKLRPTVFSPGDYICKKGDIGREMYIIKE 465
            K++I      D +K + +F+  +   + E++  +      PG++I  +GD G   Y+I  
Sbjct: 1671 KSDIQRQRLADVVKNILLFRSLDPEQMQEVLDAMFEKSVQPGEHIIDQGDDGDNFYVIDS 1492

Query: 466  GKLAVVAD-DGVTQFVVLSDGS-YFGEISIL 494
            G   +  D +G  + V   D S +FGE++++
Sbjct: 1491 GTYDIYVDVEGQAKLVGNYDNSGFFGELALM 1399

 Score = 36.6 bits (83), Expect = 0.030,   Method: Compositional matrix adjust.
 Identities = 28/118 (23%), Positives = 53/118 (44%), Gaps = 8/118 (6%)
 Frame = -3

Query: 385  LWANRKTVDEKEVLKNLPDKLKAEIAINVHLDTLKKVRIFQDCEAGLLVELVLKLRPTVF 444
            +WA  +T   + VLK    K K   ++   +  LK + +++       + +   L+   +
Sbjct: 1350 IWALDRTTFRRIVLKTAFQKRKKYESLLESVPLLKSLDLYE------RMNVADALQTRTY 1189

Query: 445  SPGDYICKKGDIGREMYIIKEGKLAVVADD--------GVTQFVVLSDGSYFGEISIL 494
              G  I K+GD    MY ++ G++ +   +        G T   VL  G YFGE++++
Sbjct: 1188 EDGVQIIKQGDAADVMYFVESGQVRIAMTNKESTDPSAGETDVTVLEKGGYFGELALI 1015
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|33859722|ref|NP_082615.1| thioredoxin-related
transmembrane protein 1 [Mus musculus]
         (278 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

06936                                                                  60   7e-10
03582                                                                  56   2e-08
18455                                                                  49   2e-06
00526                                                                  48   5e-06
07257                                                                  47   6e-06
28335                                                                  44   6e-05
15159                                                                  40   0.001
35861                                                                  39   0.003
30644                                                                  37   0.006
04510                                                                  37   0.007
21509                                                                  34   0.066
24297                                                                  30   1.6  
31953                                                                  29   1.8  
36159                                                                  29   2.2  
29832                                                                  28   3.0  
>06936
          Length = 2198

 Score = 60.5 bits (145), Expect = 7e-10,   Method: Compositional matrix adjust.
 Identities = 36/124 (29%), Positives = 65/124 (52%), Gaps = 11/124 (8%)
 Frame = +3

Query: 30  NVRVLTDENWTSLLEGE--WMIEFYAPWCPACQNLQPEWE--SFAEWGEDLEVKVAKVDV 85
           +V  L   ++ S +E     ++EF+APWC  C+ L P++E  + A    D  V +AKVD 
Sbjct: 147 DVLDLKKSDFQSTIEKHSLMLVEFFAPWCGHCKKLAPQYELAATALLKNDPPVPLAKVDC 326

Query: 86  TEQTGLSGRFIITALPSIYHCKDGEFRR-YVGPRTKKDFINFV------SDKEWKNIEPI 138
           TE+T +  ++ ++  P++   + GE  + Y GPR K   + ++      + KE K++E  
Sbjct: 327 TEETDVCSKYGVSGYPTLKVFRGGEVNKDYDGPRDKDGIVKYMAKMAGPTSKELKSVEEY 506

Query: 139 SSWF 142
             + 
Sbjct: 507 EKFL 518

 Score = 58.2 bits (139), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 36/120 (30%), Positives = 60/120 (50%), Gaps = 7/120 (5%)
 Frame = +3

Query: 22   PGAHGRRNNVRVLTDENWTSLL---EGEWMIEFYAPWCPACQNLQPEWESFAE-WGEDLE 77
            P      N V+V    N+  L+   E + +IEFYAPWC  C+ L P+++  AE    + E
Sbjct: 1164 PVPDNSENAVKVAVGRNFEELVNDPEKDVLIEFYAPWCGHCKTLAPKYDELAEKLKNEPE 1343

Query: 78   VKVAKVDVTEQTGLSGRFIITALPSIYHCKDGEF---RRYVGPRTKKDFINFVSDKEWKN 134
            + +AK+D T    +   + +   P++Y    G     ++Y G R   DF+ +++ KE  N
Sbjct: 1344 IVIAKMDAT-ANDVPPPYDVRGFPTLYFAPKGSKSSPKKYEGGREVNDFVKYLA-KEATN 1517
>03582
          Length = 1967

 Score = 55.8 bits (133), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 31/81 (38%), Positives = 48/81 (59%), Gaps = 4/81 (4%)
 Frame = +2

Query: 27  RRNNVRVLTDENWTSLL-EGEW-MIEFYAPWCPACQNLQPEWESFAEW--GEDLEVKVAK 82
           +   V VLT +N+ S + E E+ ++EFYAPWC  C+ L PE+   A+    E+ +VK+AK
Sbjct: 107 QDEGVYVLTTKNFDSFVKENEFVLVEFYAPWCGHCKALAPEYAKAAQTLKDENSDVKLAK 286

Query: 83  VDVTEQTGLSGRFIITALPSI 103
           VD T +T L     +   P++
Sbjct: 287 VDATIETSLGENMGVRGYPTL 349

 Score = 47.4 bits (111), Expect = 7e-06,   Method: Compositional matrix adjust.
 Identities = 33/104 (31%), Positives = 53/104 (50%), Gaps = 6/104 (5%)
 Frame = +3

Query: 31   VRVLTDENWTSLLEGEW---MIEFYAPWCPACQNLQPEWESFAE-WGEDLEVKVAKVDVT 86
            V+VL  +N+  +   +     +EFYAPWC  C+ L P W+  A+ + +  +V +AK+D T
Sbjct: 1131 VKVLVGKNFKEVALDKTKGVFVEFYAPWCGHCKQLAPIWDELADKFTDKADVVIAKMDST 1310

Query: 87   EQTGLSGRFIITALPSI-YHCKD-GEFRRYVGPRTKKDFINFVS 128
                   +  + + P++ Y  KD  E   Y G RT   F+ FV 
Sbjct: 1311 ANEIEEVK--VQSFPTLKYFPKDSDEVIDYNGERTLDAFVKFVE 1436
>18455
          Length = 499

 Score = 48.9 bits (115), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 23/76 (30%), Positives = 40/76 (52%), Gaps = 2/76 (2%)
 Frame = +2

Query: 45  GEWMIEFYAPWCPACQNLQPEWESFAE-WGEDLEVKVAKVDVTEQTGLSGRFIITALPSI 103
           G   ++F+APWC  CQ L P WE  A+   ++    ++K+D T+   +   F +   P++
Sbjct: 191 GNHFVKFFAPWCSHCQRLAPIWEELAKALIKEPSATISKIDCTQYRSICQDFEVKGYPTL 370

Query: 104 YHCKDG-EFRRYVGPR 118
              +DG +  +Y G R
Sbjct: 371 LWIEDGKKIEKYAGAR 418
>00526
          Length = 2428

 Score = 47.8 bits (112), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 19/43 (44%), Positives = 26/43 (60%)
 Frame = -1

Query: 174  GIPAWGSYLVFAFATVLSGLLLGLCMIFVADCLCPSKRRKPQQ 216
            GIP W  Y++FA  T++ GLL+GL ++   DCL P K     Q
Sbjct: 2398 GIPEWACYIIFAVITIIVGLLMGLIIVLCCDCLFPPKYVPAHQ 2270
>07257
          Length = 1477

 Score = 47.4 bits (111), Expect = 6e-06,   Method: Compositional matrix adjust.
 Identities = 26/84 (30%), Positives = 39/84 (46%), Gaps = 2/84 (2%)
 Frame = -3

Query: 48   MIEFYAPWCPACQNLQPEWESFAEWGEDLEVKVAKVDVTEQTGLSGRFIITALPSI--YH 105
            ++ FYAPWC  C N  P + + A     LE  V  VD    + L+ RF   A+P+I  +H
Sbjct: 1286 LVMFYAPWCHFCANTAPHYNALARAFPQLE--VLAVDTVHFSNLNARFGTVAVPNIMLFH 1113

Query: 106  CKDGEFRRYVGPRTKKDFINFVSD 129
                  R     R    F+ F+++
Sbjct: 1112 QSRSAVRFNHTERDFHTFLQFIAN 1041
>28335
          Length = 601

 Score = 44.3 bits (103), Expect = 6e-05,   Method: Compositional matrix adjust.
 Identities = 26/85 (30%), Positives = 44/85 (51%), Gaps = 4/85 (4%)
 Frame = -2

Query: 48  MIEFYAPWCPACQNLQPEWESFAEWGED-LEVKVAKVDVTEQTGLSGRFIITALPSIYHC 106
           +IEFYAPWC  CQ L+P++   A   +D  ++  AK+D T     +  + +   P+IY  
Sbjct: 486 LIEFYAPWCGHCQQLEPKYNELATLLKDEPDIVXAKIDATANDTPTP-YEVKGFPAIYFS 310

Query: 107 KD--GEF-RRYVGPRTKKDFINFVS 128
                EF ++Y G R     + +++
Sbjct: 309 PKRFKEFPKKYEGDREVDAMLKYIA 235
>15159
          Length = 1945

 Score = 40.0 bits (92), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 21/80 (26%), Positives = 45/80 (56%), Gaps = 6/80 (7%)
 Frame = +3

Query: 31  VRVLTDENWTSLLEGEWMI--EFYAPWCPACQNLQPEWESFAEWGEDLE----VKVAKVD 84
           +++ + +++   ++G  ++  +F+A WC  C+ + P+    A+W E+      VK+  VD
Sbjct: 84  IKISSADDFEKAIQGGQLVVVDFHATWCGPCKVIAPK---LAKWSEEDRFKETVKIISVD 254

Query: 85  VTEQTGLSGRFIITALPSIY 104
           V E   L+G   I+A+P+ +
Sbjct: 255 VDELEDLAGEQGISAMPTFF 314
>35861
          Length = 850

 Score = 38.5 bits (88), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 22/67 (32%), Positives = 34/67 (50%), Gaps = 4/67 (5%)
 Frame = +3

Query: 31  VRVLTDENWTSLL---EGEWMIEFYAPWCPACQNLQPEWESFAEWGEDL-EVKVAKVDVT 86
           V+VL  +N+  +      +  +EFYAPWC  C+ L P W+   E  +D  +V +AK  + 
Sbjct: 576 VKVLVSKNFKEVALDKSKDVFVEFYAPWCGHCKQLVPIWDELGEKFQDSDDVVIAKNGLH 755

Query: 87  EQTGLSG 93
            Q    G
Sbjct: 756 GQRSGGG 776
>30644
          Length = 845

 Score = 37.4 bits (85), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 15/43 (34%), Positives = 27/43 (62%), Gaps = 3/43 (6%)
 Frame = -3

Query: 31  VRVLTDENWTSLLEGE---WMIEFYAPWCPACQNLQPEWESFA 70
           V + TD+  T LL+ +    ++ FYAPWC  C+ ++P++ + A
Sbjct: 474 VHIDTDDGLTKLLKKDKSAALVMFYAPWCGYCKRMKPDFAAAA 346
>04510
          Length = 685

 Score = 37.4 bits (85), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 20/61 (32%), Positives = 34/61 (55%), Gaps = 4/61 (6%)
 Frame = +2

Query: 27  RRNNVRVLTDENWTSLLEGE--WMIEFYAPWCPACQNLQPEWE--SFAEWGEDLEVKVAK 82
           + ++V  L   ++ S +E     ++EF+APWC  C+ L P++E  + A    D  V +AK
Sbjct: 344 QASDVLDLKKSDFQSTIEKHSLMLVEFFAPWCGHCKKLAPQYELAATALLKNDPPVPLAK 523

Query: 83  V 83
           V
Sbjct: 524 V 526
>21509
          Length = 754

 Score = 33.9 bits (76), Expect = 0.066,   Method: Compositional matrix adjust.
 Identities = 14/44 (31%), Positives = 25/44 (56%), Gaps = 2/44 (4%)
 Frame = -1

Query: 29  NNVRVLTDENWTSLLEGE--WMIEFYAPWCPACQNLQPEWESFA 70
           ++V  LTD  + S +      ++ FYAPWC  C+ ++P + + A
Sbjct: 361 SDVNHLTDATFESFIAANRRTLVMFYAPWCGHCKKMKPAYMAAA 230
>24297
          Length = 982

 Score = 29.6 bits (65), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 16/53 (30%), Positives = 26/53 (49%)
 Frame = -3

Query: 128 SDKEWKNIEPISSWFGPSSVLMTMMSALFQLSVYIRTSHSYFVHDLGIPAWGS 180
           S  E+ +  P+  +F    +L  M   +  L  Y+   H YF+H+L +P  GS
Sbjct: 680 SSFEYNSPHPVDLFFTRKQILYCMRILVHFLYNYLYYRH-YFLHNLRVPKKGS 525
>31953
          Length = 1685

 Score = 29.3 bits (64), Expect = 1.8,   Method: Compositional matrix adjust.
 Identities = 15/38 (39%), Positives = 18/38 (47%)
 Frame = +3

Query: 100 LPSIYHCKDGEFRRYVGPRTKKDFINFVSDKEWKNIEP 137
           L  + H     F +YV P  KK      S K W+NIEP
Sbjct: 840 LRELRHMAQLNFPKYVEPLQKKQVTEKESGKLWRNIEP 953
>36159
          Length = 369

 Score = 28.9 bits (63), Expect = 2.2,   Method: Compositional matrix adjust.
 Identities = 14/33 (42%), Positives = 20/33 (60%), Gaps = 1/33 (3%)
 Frame = -1

Query: 53  APWCPACQNLQPEWESFAEWGEDL-EVKVAKVD 84
           APWC  C+ L P W+   E  +D  +V +AK+D
Sbjct: 102 APWCGHCKQLVPIWDELGEKFQDSDDVVIAKMD 4
>29832
          Length = 367

 Score = 28.5 bits (62), Expect = 3.0,   Method: Compositional matrix adjust.
 Identities = 14/38 (36%), Positives = 24/38 (63%)
 Frame = -3

Query: 168 YFVHDLGIPAWGSYLVFAFATVLSGLLLGLCMIFVADC 205
           +++H++ IP+  +Y VF+   +   LLL LC +FV  C
Sbjct: 176 FYIHNMSIPSLSTY-VFSRFCLFVRLLLSLCFLFVRCC 66
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6755983|ref|NP_036168.1| visinin-like 1 [Mus
musculus]
         (191 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

26019                                                                  60   7e-10
14594                                                                  40   6e-04
07678                                                                  39   0.001
00167                                                                  39   0.001
14366                                                                  37   0.004
38338                                                                  37   0.006
07198                                                                  36   0.008
17484                                                                  34   0.040
15966                                                                  33   0.088
05237                                                                  33   0.089
13551                                                                  32   0.14 
03732                                                                  30   0.51 
27864                                                                  30   0.60 
01773                                                                  30   0.80 
33397                                                                  29   1.3  
09410                                                                  29   1.3  
02929                                                                  28   1.8  
18571                                                                  28   1.9  
12128                                                                  27   3.7  
08380                                                                  27   7.0  
12214                                                                  26   9.2  
19912                                                                  26   9.5  
>26019
          Length = 1561

 Score = 59.7 bits (143), Expect = 7e-10,   Method: Compositional matrix adjust.
 Identities = 34/96 (35%), Positives = 54/96 (56%), Gaps = 1/96 (1%)
 Frame = +2

Query: 40  SGRLNLEEFQQLYVKFFPYGDASKFAQHAFRTFDKNGDGTIDFREFICALS-ITSRGSFE 98
           SG L+++EF  L     P    +   Q     FD +G+G +DF+EFI  +S  + +G  E
Sbjct: 140 SGSLSIDEFMSL-----PELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGISQFSVKGDKE 304

Query: 99  QKLNWAFNMYDLDGDGKITRVEMLEIIEAIYKMVGT 134
            KL +AF +YD+D DG I+  E+ ++++    MVG 
Sbjct: 305 SKLRFAFKIYDMDKDGYISNGELFQVLKM---MVGN 403
>14594
          Length = 1014

 Score = 40.0 bits (92), Expect = 6e-04,   Method: Compositional matrix adjust.
 Identities = 23/88 (26%), Positives = 43/88 (48%)
 Frame = +3

Query: 40  SGRLNLEEFQQLYVKFFPYGDASKFAQHAFRTFDKNGDGTIDFREFICALSITSRGSFEQ 99
           +G ++ EEF  +  +     D  +  + AFR FDK+G+G I   E    ++       ++
Sbjct: 591 NGTIDFEEFLHMMARKMKDTDCEEELREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDE 770

Query: 100 KLNWAFNMYDLDGDGKITRVEMLEIIEA 127
           +++      DLDGDG +   E + ++ A
Sbjct: 771 EVDEMIKEADLDGDGMVNYEEFVTMMTA 854

 Score = 36.2 bits (82), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 21/60 (35%), Positives = 29/60 (48%)
 Frame = +3

Query: 66  QHAFRTFDKNGDGTIDFREFICALSITSRGSFEQKLNWAFNMYDLDGDGKITRVEMLEII 125
           + AF  FDK+GDGTI   E    +    +   E +L    N  D DG+G I   E L ++
Sbjct: 450 KEAFSLFDKDGDGTITTSELGTVMRSLGQNPTENELQDMINEVDADGNGTIDFEEFLHMM 629
>07678
          Length = 958

 Score = 39.3 bits (90), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 38/132 (28%), Positives = 61/132 (46%), Gaps = 3/132 (2%)
 Frame = +1

Query: 43  LNLEEFQQLYVKFFPYGDASKFAQHAFRTFDKNGDGTIDFREFICALSITSRGSFEQKLN 102
           L+ +EF++   +F          Q  F  FDK+  GTIDF EF+  L        +  + 
Sbjct: 370 LDFKEFKKGITEFGLTQFEGDVIQEMFTCFDKDZSGTIDFDEFLVKLRPPMSQMRKDLIQ 549

Query: 103 WAFNMYDLDGDGKITRVEMLEIIEAIYKMVGTVIMMKMNEDGLTPEQRVDKIF-SKMDK- 160
            AF   D  GDG +T    +E ++ +Y +      +    +G   E+R+ +IF    D  
Sbjct: 550 RAFQKLDKTGDGVVT----VEDLKGVYNVTKHPKYL----NGEWTEERILRIFLDSFDSP 705

Query: 161 -NKDDQITLDEF 171
            +KD +IT +EF
Sbjct: 706 NDKDGKITKEEF 741

 Score = 27.7 bits (60), Expect = 3.3,   Method: Compositional matrix adjust.
 Identities = 26/105 (24%), Positives = 46/105 (43%), Gaps = 1/105 (0%)
 Frame = +1

Query: 69  FRTFDKNGDGTIDFREFICALSITSRGSFEQK-LNWAFNMYDLDGDGKITRVEMLEIIEA 127
           F+  D +G+ ++DF+EF   ++      FE   +   F  +D D  G I   E L  +  
Sbjct: 337 FKIMDDDGNRSLDFKEFKKGITEFGLTQFEGDVIQEMFTCFDKDZSGTIDFDEFLVKLRP 516

Query: 128 IYKMVGTVIMMKMNEDGLTPEQRVDKIFSKMDKNKDDQITLDEFK 172
                    M +M +D       + + F K+DK  D  +T+++ K
Sbjct: 517 --------PMSQMRKD------LIQRAFQKLDKTGDGVVTVEDLK 609
>00167
          Length = 2176

 Score = 39.3 bits (90), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 25/53 (47%), Positives = 29/53 (54%), Gaps = 1/53 (1%)
 Frame = +3

Query: 66  QHAFRTFDKNGDGTIDFREFICALSITSRGSFEQKL-NWAFNMYDLDGDGKIT 117
              FR FDK+G GT+DF EF+ AL       F +KL   AF   D  GDG IT
Sbjct: 849 NEVFRRFDKDGTGTLDFEEFLLALR-PKMNEFRRKLVKKAFAKMDKTGDGIIT 1004
>14366
          Length = 499

 Score = 37.4 bits (85), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 21/84 (25%), Positives = 43/84 (51%)
 Frame = -3

Query: 43  LNLEEFQQLYVKFFPYGDASKFAQHAFRTFDKNGDGTIDFREFICALSITSRGSFEQKLN 102
           L L+E   +  K+    + S   + AFR FDK G+G I+  E    L+       +++++
Sbjct: 311 LTLQEVIAIVTKYEFAPETSDNLREAFRIFDKEGNGMINAAELRHVLTHLGEKLSDEEVD 132

Query: 103 WAFNMYDLDGDGKITRVEMLEIIE 126
                 D+ GDG+++  + ++++E
Sbjct: 131 EMIREADISGDGQVSYNDFVKVME 60
>38338
          Length = 463

 Score = 36.6 bits (83), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 19/49 (38%), Positives = 25/49 (51%)
 Frame = -2

Query: 68  AFRTFDKNGDGTIDFREFICALSITSRGSFEQKLNWAFNMYDLDGDGKI 116
           AF  FDK+GDGTI  +E    +    +   E +L    N  D DG+G I
Sbjct: 153 AFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTI 7
>07198
          Length = 1675

 Score = 36.2 bits (82), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 20/82 (24%), Positives = 46/82 (56%)
 Frame = -3

Query: 41  GRLNLEEFQQLYVKFFPYGDASKFAQHAFRTFDKNGDGTIDFREFICALSITSRGSFEQK 100
           G +++EEF    +     GD    ++ +F+ +DK+ DG++   E +  ++ +S    + +
Sbjct: 335 GTISMEEF----MPEGATGDTRTSSEESFKNYDKDKDGSLSLEEAMEWINPSSDEHADVE 168

Query: 101 LNWAFNMYDLDGDGKITRVEML 122
           +   F + D++ DGK+++ E+L
Sbjct: 167 VEHLFTIGDVNHDGKLSKDEIL 102
>17484
          Length = 471

 Score = 33.9 bits (76), Expect = 0.040,   Method: Compositional matrix adjust.
 Identities = 26/82 (31%), Positives = 37/82 (45%), Gaps = 1/82 (1%)
 Frame = -3

Query: 45  LEEFQQLYVKFFPYG-DASKFAQHAFRTFDKNGDGTIDFREFICALSITSRGSFEQKLNW 103
           +EEF  L V     G +  K  + AFR FD+NGDG I   E   A++   +   +  +  
Sbjct: 328 VEEFLPLIVGRMKGGSEKDKEMRDAFRAFDQNGDGVISISELRQAMAKMGQKLSDADVES 149

Query: 104 AFNMYDLDGDGKITRVEMLEII 125
                D DGDG +   E  + I
Sbjct: 148 IIRDVDKDGDGFVNYEEFTKFI 83

 Score = 28.5 bits (62), Expect = 1.8,   Method: Compositional matrix adjust.
 Identities = 14/34 (41%), Positives = 20/34 (58%)
 Frame = -1

Query: 106 NMYDLDGDGKITRVEMLEIIEAIYKMVGTVIMMK 139
           N YD DG+GKITR E   ++    +M+G  +  K
Sbjct: 471 NQYDQDGNGKITRNEFRSVV----RMLGHSLSEK 382
>15966
          Length = 362

 Score = 32.7 bits (73), Expect = 0.088,   Method: Compositional matrix adjust.
 Identities = 36/117 (30%), Positives = 49/117 (41%), Gaps = 1/117 (0%)
 Frame = +2

Query: 60  DASKFAQHA-FRTFDKNGDGTIDFREFICALSITSRGSFEQKLNWAFNMYDLDGDGKITR 118
           D S+ ++HA F      GD  I F EF   L       F QKL   F   D  GDG + R
Sbjct: 20  DESRRSRHARFFVVPSCGDKRITFEEFCKGLDQIV--MFVQKLAELFKAKDKSGDGYLDR 193

Query: 119 VEMLEIIEAIYKMVGTVIMMKMNEDGLTPEQRVDKIFSKMDKNKDDQITLDEFKEAA 175
            E+    +A+    G     K   D ++       I    DKN D++I  +EF +A 
Sbjct: 194 DEL----KALLDESG----QKFTADDVSA------ILKSADKNNDNKICFEEFVDAC 322
>05237
          Length = 472

 Score = 32.7 bits (73), Expect = 0.089,   Method: Compositional matrix adjust.
 Identities = 16/60 (26%), Positives = 33/60 (55%)
 Frame = +3

Query: 66  QHAFRTFDKNGDGTIDFREFICALSITSRGSFEQKLNWAFNMYDLDGDGKITRVEMLEII 125
           + AFR FDK+G+G I   E    ++       +++++      D+DGDG++   E ++++
Sbjct: 36  REAFRVFDKDGNGFISASELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVKMM 215
>13551
          Length = 529

 Score = 32.3 bits (72), Expect = 0.14,   Method: Compositional matrix adjust.
 Identities = 32/110 (29%), Positives = 50/110 (45%), Gaps = 7/110 (6%)
 Frame = +1

Query: 69  FRTFDKNGDGTIDFREFICALSITSRGSFEQK-------LNWAFNMYDLDGDGKITRVEM 121
            R  DKN DG +DF EF CAL    R   +++       +N  F      GD  I+  +M
Sbjct: 94  LREEDKNVDGCLDFEEF-CALYKKKRQKEDKRKEELLMSVNQLFPSSQ-SGDDTISLDKM 267

Query: 122 LEIIEAIYKMVGTVIMMKMNEDGLTPEQRVDKIFSKMDKNKDDQITLDEF 171
             +++ +  M G      M    LT +  +D I  K+++N D+ I+  E 
Sbjct: 268 AGLLKQMNNMPGLCSEATM---ALT-DTDIDSIIGKINRNNDNTISKSEL 405
>03732
          Length = 1114

 Score = 30.4 bits (67), Expect = 0.51,   Method: Compositional matrix adjust.
 Identities = 32/127 (25%), Positives = 49/127 (38%), Gaps = 30/127 (23%)
 Frame = -1

Query: 20   TEFNEHELKQWYKGFLKDCPSGRLNLEEFQQLY--------------------------- 52
            T FN   ++     F +D  SG +N +EFQ L+                           
Sbjct: 1006 TPFNPETVRLMIGMFDRD-NSGTINFQEFQALWKYVTDWQNCFRSYDRDNSGSIDRNELK 830

Query: 53   --VKFFPYGDASKFAQHAFRTFDKNGDGTIDFREFI-CALSITSRGSFEQKLNWAFNMYD 109
              +  F Y  + +F     + FD+ G GT+ F +FI C + +       Q L  +F  +D
Sbjct: 829  NALTGFGYRLSDRFFDVLVKKFDRQGKGTVAFDDFIQCCVVL-------QTLTTSFRTHD 671

Query: 110  LDGDGKI 116
             D DG I
Sbjct: 670  QDQDGWI 650

 Score = 29.3 bits (64), Expect = 0.92,   Method: Compositional matrix adjust.
 Identities = 25/88 (28%), Positives = 38/88 (43%), Gaps = 6/88 (6%)
 Frame = -1

Query: 40   SGRLNLEEFQQLYVKFFPYGDASKFAQHAFR----TFDKNGDGTIDFREFICALSITSRG 95
            SG +++ E QQ        G  + F     R     FD++  GTI+F+EF        + 
Sbjct: 1060 SGNISVNELQQA----LSNGTWTPFNPETVRLMIGMFDRDNSGTINFQEF--------QA 917

Query: 96   SFEQKLNW--AFNMYDLDGDGKITRVEM 121
             ++   +W   F  YD D  G I R E+
Sbjct: 916  LWKYVTDWQNCFRSYDRDNSGSIDRNEL 833
>27864
          Length = 343

 Score = 30.0 bits (66), Expect = 0.60,   Method: Compositional matrix adjust.
 Identities = 25/88 (28%), Positives = 36/88 (40%), Gaps = 6/88 (6%)
 Frame = +1

Query: 40  SGRLNLEEFQQLYVKFFPYGDASKFAQHAFR----TFDKNGDGTIDFREFICALSITSRG 95
           SG +++ E QQ        G  + F     R     FD++  GTI+F+EF       +  
Sbjct: 55  SGNISVNELQQALSN----GTWTPFNPETVRLMIGMFDRDNSGTINFQEFQALWKYVT-- 216

Query: 96  SFEQKLNW--AFNMYDLDGDGKITRVEM 121
                 +W   F  YD D  G I R E+
Sbjct: 217 ------DWQNCFRSYDRDNSGSIDRNEL 282
>01773
          Length = 1950

 Score = 29.6 bits (65), Expect = 0.80,   Method: Compositional matrix adjust.
 Identities = 44/158 (27%), Positives = 65/158 (41%), Gaps = 1/158 (0%)
 Frame = +1

Query: 18  KSTEFNEHELKQWYKGFLKDCPSGRLNLEEFQQLYVKFFPYGDASKFAQHAFRTFD-KNG 76
           K T  N    KQ +K   K+   G L ++E ++L+ +       S+ A   F  FD   G
Sbjct: 133 KGTGPNTDAYKQLFKEADKN-NDGYLEIKELRELFKRNGSSLSDSQIAD-TFVFFDGPRG 306

Query: 77  DGTIDFREFICALSITSRGSFEQKLNWAFNMYDLDGDGKITRVEMLEIIEAIYKMVGTVI 136
           D  I F  F   L       F QKL   F   D  GDG + R E+  +++   +      
Sbjct: 307 DKRITFEXFCKGLDQIVM--FVQKLAELFKAKDKSGDGYLDRDELKALLDESGQ------ 462

Query: 137 MMKMNEDGLTPEQRVDKIFSKMDKNKDDQITLDEFKEA 174
             K   D ++       I    DKN D++I  +EF +A
Sbjct: 463 --KFTADDVSA------ILKSADKNNDNKICFEEFVDA 552
>33397
          Length = 1723

 Score = 28.9 bits (63), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 12/18 (66%), Positives = 13/18 (72%)
 Frame = +3

Query: 68  AFRTFDKNGDGTIDFREF 85
           AFR FD NGDG +D  EF
Sbjct: 207 AFRMFDINGDGELDLEEF 260

 Score = 28.9 bits (63), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 13/39 (33%), Positives = 24/39 (61%)
 Frame = +3

Query: 78  GTIDFREFICALSITSRGSFEQKLNWAFNMYDLDGDGKI 116
           G I F ++I  L++ S  +  +    AF M+D++GDG++
Sbjct: 135 GLISFSDYIFLLTVLS--TPPRNFEIAFRMFDINGDGEL 245
>09410
          Length = 1079

 Score = 28.9 bits (63), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 14/35 (40%), Positives = 18/35 (51%)
 Frame = -1

Query: 28  KQWYKGFLKDCPSGRLNLEEFQQLYVKFFPYGDAS 62
            QW+K  L+   S  +NL    Q YV  F YG+ S
Sbjct: 518 SQWHKTXLESISSYXINLVXLDQDYVICFLYGETS 414
>02929
          Length = 1353

 Score = 28.5 bits (62), Expect = 1.8,   Method: Compositional matrix adjust.
 Identities = 22/83 (26%), Positives = 41/83 (49%), Gaps = 1/83 (1%)
 Frame = +2

Query: 47  EFQQLYVKFFPYGDASKF-AQHAFRTFDKNGDGTIDFREFICALSITSRGSFEQKLNWAF 105
           +F+    K+  +  A KF     FR  DK+GDG +   EF+  +  +   +   +LN  F
Sbjct: 125 DFESWRGKYLKWIQAKKFRVTDFFRRQDKDGDGFLTEEEFVNGMMQSRFPTNRTELNAVF 304

Query: 106 NMYDLDGDGKITRVEMLEIIEAI 128
           +++D +  G I   E  + ++A+
Sbjct: 305 DIFDREKRGLI---EYKDFVDAL 364
>18571
          Length = 821

 Score = 28.5 bits (62), Expect = 1.9,   Method: Compositional matrix adjust.
 Identities = 12/26 (46%), Positives = 15/26 (57%)
 Frame = -1

Query: 165 QITLDEFKEAAKSDPSIVLLLQCDIQ 190
           +  +      A +DPSIV LLQCD Q
Sbjct: 782 ETVVGRVHRGAMNDPSIVRLLQCDPQ 705

 Score = 26.2 bits (56), Expect = 8.2,   Method: Compositional matrix adjust.
 Identities = 11/27 (40%), Positives = 18/27 (66%)
 Frame = -2

Query: 155 FSKMDKNKDDQITLDEFKEAAKSDPSI 181
           F +MDKN D +++L+EF E   + P +
Sbjct: 811 FRQMDKNLDGKLSLEEFIEGP*TIPPL 731
>12128
          Length = 1429

 Score = 27.3 bits (59), Expect = 3.7,   Method: Compositional matrix adjust.
 Identities = 19/58 (32%), Positives = 26/58 (44%)
 Frame = -2

Query: 134  TVIMMKMNEDGLTPEQRVDKIFSKMDKNKDDQITLDEFKEAAKSDPSIVLLLQCDIQK 191
            T I     EDGLTP Q +  +       KD  +T+ + K     DP   L+ +C  QK
Sbjct: 1206 TCITSSQTEDGLTPSQEICPLSYNCSXQKDFLLTISKAK-----DP---LIHKCSSQK 1057
>08380
          Length = 1236

 Score = 26.6 bits (57), Expect = 7.0,   Method: Compositional matrix adjust.
 Identities = 24/95 (25%), Positives = 39/95 (41%), Gaps = 15/95 (15%)
 Frame = -1

Query: 72  FDKNGDGTIDFREFICALSITSRGSFEQKLN--WA-------FNMYDLDGDGKITRVEML 122
            D NGDG +   EF         G   Q ++  W            DLD DGK+T+ E+ 
Sbjct: 453 IDTNGDGVVTEEEFSALPPGEVEGEEYQAMDKQWQKERQEEFRTAIDLDHDGKVTKDEIK 274

Query: 123 EI------IEAIYKMVGTVIMMKMNEDGLTPEQRV 151
           +       ++A+ +    V  M  ++DG+  +  V
Sbjct: 273 KYMDPRNPLQALLEAKSLVSYMDDDKDGMISQAEV 169
>12214
          Length = 654

 Score = 26.2 bits (56), Expect = 9.2,   Method: Compositional matrix adjust.
 Identities = 26/104 (25%), Positives = 41/104 (39%)
 Frame = -3

Query: 72  FDKNGDGTIDFREFICALSITSRGSFEQKLNWAFNMYDLDGDGKITRVEMLEIIEAIYKM 131
           FD++  GTID  EF       S   + Q+    F  YD +  G I   E+    +A Y+ 
Sbjct: 628 FDRDMSGTIDINEF------QSLWQYIQQWRSTFERYDSNRSGSIEGNEL----QAAYQQ 479

Query: 132 VGTVIMMKMNEDGLTPEQRVDKIFSKMDKNKDDQITLDEFKEAA 175
           +G  +  +           V  +  K D      +TLD F ++ 
Sbjct: 478 MGFNVSPRF----------VQTVLYKFDHFGRRSLTLDNFIQSC 377
>19912
          Length = 865

 Score = 26.2 bits (56), Expect = 9.5,   Method: Compositional matrix adjust.
 Identities = 22/74 (29%), Positives = 35/74 (47%), Gaps = 4/74 (5%)
 Frame = +2

Query: 53  VKFFPYGDASKF-AQHAFRTFDKNGDGTI---DFREFICALSITSRGSFEQKLNWAFNMY 108
           VK   Y D++       F  FDK G  +I    FR+ +   SI   G    ++++  +  
Sbjct: 635 VKLMAYIDSNNLRLVDFFNKFDKEGTMSITRDQFRQGLTEASIPLAGD---EVDFLLDEL 805

Query: 109 DLDGDGKITRVEML 122
           D DGDG+I   E++
Sbjct: 806 DRDGDGEINYSELV 847
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6671664|ref|NP_031623.1| calnexin [Mus musculus]
         (591 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

22772                                                                  62   8e-10
30091                                                                  47   2e-05
23413                                                                  31   1.3  
>22772
          Length = 365

 Score = 61.6 bits (148), Expect = 8e-10,   Method: Compositional matrix adjust.
 Identities = 38/85 (44%), Positives = 46/85 (54%)
 Frame = +1

Query: 312 KIPDEEATKPEGWLDDEPEYIPDPDAEKPXXXXXXXXXXXXAPQIANPKCESAPGCGVWQ 371
           KI D E  KPE W  D+PE+IPDPDA+KP                           G W+
Sbjct: 124 KIADPEDKKPEDW--DKPEHIPDPDAKKPDDWDDEMD-------------------GEWE 240

Query: 372 RPMIDNPNYKGKWKPPMIDNPNYQG 396
            PMIDNP Y+G+WKP  IDNP+Y+G
Sbjct: 241 PPMIDNPEYQGEWKPKQIDNPDYKG 315

 Score = 52.0 bits (123), Expect = 7e-07,   Method: Compositional matrix adjust.
 Identities = 42/123 (34%), Positives = 55/123 (44%)
 Frame = +1

Query: 261 GNLLNDMTPPVNPSREIEDPEDRKPEDWDERPKIADPDAVKPDDWDEDAPSKIPDEEATK 320
           G    + T P   +++I DPED+KPEDWD+   I DPDA KPDDWD++            
Sbjct: 79  GTTARNPTSPTAGAKKIADPEDKKPEDWDKPEHIPDPDAKKPDDWDDE------------ 222

Query: 321 PEGWLDDEPEYIPDPDAEKPXXXXXXXXXXXXAPQIANPKCESAPGCGVWQRPMIDNPNY 380
               +D E E                       P I NP+ +     G W+   IDNP+Y
Sbjct: 223 ----MDGEWE----------------------PPMIDNPEYQ-----GEWKPKQIDNPDY 309

Query: 381 KGK 383
           KGK
Sbjct: 310 KGK 318
>30091
          Length = 447

 Score = 47.0 bits (110), Expect = 2e-05,   Method: Composition-based stats.
 Identities = 34/116 (29%), Positives = 55/116 (47%)
 Frame = -2

Query: 71  YFADSFDRGSLSGWILSKAKKDDTDDEIAKYDGKWEVDEMKETKLPGDKGLVLMSRAKHH 130
           +F + F+ G  S W  S  K  +   +     GK+  D  K      DKG+     A+ +
Sbjct: 320 HFVEKFEEGWESRWTDSTHKGGE-QGKFKLSAGKFYGDAEK------DKGIQTSQDARFY 162

Query: 131 AISAKLNKPFLFDTKPLIVQYEVNFQNGIECGGAYVKLLSKTAELSLDQFHDKTPY 186
            +SAK +  F  + K L++Q+ V  +  I+CGG Y K+ S  ++L     H  +PY
Sbjct: 161 GLSAKFDT-FSNEGKTLVIQFTVKHEQNIDCGGGYAKIFS--SDLDQADMHGDSPY 3
>23413
          Length = 2343

 Score = 31.2 bits (69), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 45/154 (29%), Positives = 65/154 (42%), Gaps = 13/154 (8%)
 Frame = +2

Query: 134  AKLNKPFLFDTKPLIVQYEVNFQNGIECGGAYVKLLSKTAELSLDQFH-DKTPYTIMFGP 192
            A L+   +FD     +++E     G E GGA   L+ +    SLD FH D  P  + F  
Sbjct: 1796 AGLHLFLIFD----FIKHEGLLVLGQELGGA*--LVQEKGVNSLDVFHLDLRP--LAFAA 1951

Query: 193  DKCGEDYKLHFIFRHKNPKTGVYEEKHAKRPDADLKTYFTDKKTHLYTLILNPD--NSFE 250
            D+ G   +L+          GV E    +  DA L  +     THL+ L+L PD  N F+
Sbjct: 1952 DEVGSGDELY----------GVAE----RSLDAYLGQHCQRIVTHLHVLLLTPDLENLFD 2089

Query: 251  ILV--------DQSV--VNSGNLLNDMTPPVNPS 274
             L+        +QSV  VN   +   +    NP 
Sbjct: 2090 FLLIVRCGGDDEQSVQQVNGHTVRTHVMSAANPG 2191
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|16716607|ref|NP_444501.1| regulating synaptic
membrane exocytosis 2 [Mus musculus]
         (1530 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

16549                                                                  63   1e-09
29179                                                                  48   2e-05
31935                                                                  43   0.001
30040                                                                  35   0.21 
13155                                                                  31   4.5  
18800                                                                  30   9.9  
>16549
          Length = 607

 Score = 62.8 bits (151), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 35/109 (32%), Positives = 59/109 (54%), Gaps = 3/109 (2%)
 Frame = +2

Query: 1391 LEVEIIRARGLVVKPGSKTLPAPYVKVYLLDNGVCIAKKKTKVARKTLEPLYQQLLSF-- 1448
            L + ++  R L     S  LP+PYVK YLL +     K+KTK+ + ++ P + ++L +  
Sbjct: 8    LHIMVMHVRDLA---RSAELPSPYVKTYLLPDPEKQTKRKTKIVKHSVHPTFNEVLQYRM 178

Query: 1449 -EESPQGRVLQIIVWGDYGRMDHKSFMGVAQILLDELELSNMVIGWFKL 1496
             E   + R LQ+ VW D+  +   +F+G   + L +LELS+    W+ L
Sbjct: 179  KETETRHRTLQVTVW-DHDMLKENNFLGAVYLRLRDLELSDDTAKWYTL 322

 Score = 52.4 bits (124), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 35/111 (31%), Positives = 54/111 (48%), Gaps = 1/111 (0%)
 Frame = +2

Query: 831 LIVTILGAKDLPSREDGRPRNPYVKIYFLPDRSDXXXXXXXXXXXXLEPKWNQTFIYSPV 890
           L + ++  +DL +R    P +PYVK Y LPD               + P +N+   Y  +
Sbjct: 8   LHIMVMHVRDL-ARSAELP-SPYVKTYLLPDPEKQTKRKTKIVKHSVHPTFNEVLQYR-M 178

Query: 891 HRREFRERMLEITLWDQARVREEESEFLGEILIEL-ETALLDDEPHWYKLQ 940
              E R R L++T+WD   ++  E+ FLG + + L +  L DD   WY LQ
Sbjct: 179 KETETRHRTLQVTVWDHDMLK--ENNFLGAVYLRLRDLELSDDTAKWYTLQ 325
>29179
          Length = 1113

 Score = 48.1 bits (113), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 34/126 (26%), Positives = 55/126 (43%), Gaps = 1/126 (0%)
 Frame = -3

Query: 816 GQLSIKLWFDKVGHQLIVTILGAKDLPSREDGRPRNPYVKIYFLPDRSDXXXXXXXXXXX 875
           G++   L +D     L + I+ A DLP+++     +PYVKI  LPD+             
Sbjct: 538 GRIQFGLMYDFQNLTLTLRIIRAVDLPAKDVTGTSDPYVKILLLPDKK--HKLLTKVKKR 365

Query: 876 XLEPKWNQTFIYSPVHRREFRERMLEITLWDQARVREEESEFLGEILIELETALLDDEP- 934
            L P WN+ F++      +  E+ L + + D  R   ++   +GE  + L    L   P 
Sbjct: 364 NLNPHWNECFLFEGWPHNKLLEKTLYLQVIDYDRFSRDDP--IGETYLPLNEIDLSQSPV 191

Query: 935 HWYKLQ 940
            W  LQ
Sbjct: 190 SWKYLQ 173
>31935
          Length = 554

 Score = 42.7 bits (99), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 28/111 (25%), Positives = 49/111 (44%)
 Frame = -3

Query: 816 GQLSIKLWFDKVGHQLIVTILGAKDLPSREDGRPRNPYVKIYFLPDRSDXXXXXXXXXXX 875
           G++ + + +     +L VTI    ++P R+     +PYVK++ LP RS            
Sbjct: 537 GRIQLTITYSAQRQKLDVTIHKIMNIPLRDPSSIPDPYVKLHLLPGRSKESKRKTSIIKD 358

Query: 876 XLEPKWNQTFIYSPVHRREFRERMLEITLWDQARVREEESEFLGEILIELE 926
              P ++ +F Y  +   E R   LE+T+  Q       S  +G + I L+
Sbjct: 357 NCNPVYDASFEYL-ISISELRHTELEVTVCTQKGFLSSGSPIIGMLKIPLD 208

 Score = 35.4 bits (80), Expect = 0.17,   Method: Compositional matrix adjust.
 Identities = 35/132 (26%), Positives = 67/132 (50%), Gaps = 9/132 (6%)
 Frame = -3

Query: 1376 AMGDIQVGMM--DKKGQLEVEIIRARGLVVKPGSKTLPAPYVKVYLLDNGVCIAKKKTKV 1433
             +G IQ+ +    ++ +L+V I +   + ++  S ++P PYVK++LL      +K+KT +
Sbjct: 543  GLGRIQLTITYSAQRQKLDVTIHKIMNIPLRDPS-SIPDPYVKLHLLPGRSKESKRKTSI 367

Query: 1434 ARKTLEPLY----QQLLSFEESPQGRVLQIIVWGDYGRMDHKS-FMGVAQILLDELELSN 1488
             +    P+Y    + L+S  E      L++ V    G +   S  +G+ +I LD+ E++ 
Sbjct: 366  IKDNCNPVYDASFEYLISISELRHTE-LEVTVCTQKGFLSSGSPIIGMLKIPLDDSEITT 190

Query: 1489 M--VIGWFKLFP 1498
               +  WF L P
Sbjct: 189  PAGLKSWFDLEP 154
>30040
          Length = 652

 Score = 35.0 bits (79), Expect = 0.21,   Method: Composition-based stats.
 Identities = 21/71 (29%), Positives = 41/71 (57%), Gaps = 2/71 (2%)
 Frame = -3

Query: 1380 IQVGMMDKKGQLEVEIIRARGLVVKPGSKTLPA--PYVKVYLLDNGVCIAKKKTKVARKT 1437
            I +  +    +L V +++A+ L +   S + P+  P+V+V LL  G  + +KKT V R +
Sbjct: 644  ISLSYLPAAERLTVVLMKAKDLKM---STSHPSADPFVRVSLLVEGKKVKRKKTSVRRAS 474

Query: 1438 LEPLYQQLLSF 1448
            + P++ + L+F
Sbjct: 473  INPVWNEALAF 441
>13155
          Length = 663

 Score = 30.8 bits (68), Expect = 4.5,   Method: Compositional matrix adjust.
 Identities = 22/91 (24%), Positives = 40/91 (43%), Gaps = 23/91 (25%)
 Frame = -2

Query: 1429 KKTKVARKTLEPLYQQLLSFEESPQGRV---------------LQIIVWGD--------Y 1465
            ++T V +KT+ P + ++ SF+ + +G+                L +  W D         
Sbjct: 296  RRTAVRKKTICPQFDEVFSFDLNNRGQNQDRNNYSFDDVYEGELSVSXWHDDSRVSREVL 117

Query: 1466 GRMDHKSFMGVAQILLDELELSNMVIGWFKL 1496
            G M   SF+G  +I L +L+L+     W+ L
Sbjct: 116  GNMFPGSFLGEVKIALRDLDLATAHTAWYCL 24
>18800
          Length = 444

 Score = 29.6 bits (65), Expect = 9.9,   Method: Compositional matrix adjust.
 Identities = 16/42 (38%), Positives = 21/42 (50%)
 Frame = +1

Query: 278 SVSRDQNRRYEQSEEREDYSQYVPSDGTMPRSPSDYADRRSQ 319
           SV    +R +     R D+S Y P  G+ PR+P DY   R Q
Sbjct: 34  SVHGG*SRGFWHGPGRSDWSGYNPE*GSPPRTPGDYLASRFQ 159
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|21312244|ref|NP_082579.1| PDZ domain containing 11
[Mus musculus]
         (140 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

20073                                                                  58   1e-09
38751                                                                  45   1e-05
01502                                                                  40   3e-04
02951                                                                  40   3e-04
29705                                                                  39   8e-04
03831                                                                  37   0.002
08480                                                                  37   0.004
26556                                                                  35   0.007
26948                                                                  31   0.21 
20530                                                                  30   0.36 
34468                                                                  29   0.74 
26154                                                                  28   1.1  
26680                                                                  27   2.9  
13677                                                                  26   7.0  
00956                                                                  25   8.8  
>20073
          Length = 582

 Score = 58.2 bits (139), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 33/73 (45%), Positives = 46/73 (63%), Gaps = 2/73 (2%)
 Frame = +3

Query: 58  LGFNIRGGKASQLGIFISKVIPDSDAHRAG-LQEGDQVLAVNDVDFQDIEHSKAVEILKT 116
           LGFN+ GGK     I+IS++IP   A R   L+ GDQ+L+VN V  +   H KAVE+LK 
Sbjct: 6   LGFNVMGGKEQSSPIYISRIIPGGVADRLNCLKRGDQLLSVNGVSVEGEYHEKAVELLKL 185

Query: 117 AR-EISMRVRFFP 128
           A+  + + VR+ P
Sbjct: 186 AQGSVRLVVRYTP 224
>38751
          Length = 329

 Score = 45.1 bits (105), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 24/78 (30%), Positives = 40/78 (51%)
 Frame = +3

Query: 60  FNIRGGKASQLGIFISKVIPDSDAHRAGLQEGDQVLAVNDVDFQDIEHSKAVEILKTARE 119
             I+GGK     I +  +     A + GL  GD++L VN  DF  + H++AV I++ A  
Sbjct: 3   VGIKGGKEYGTPIVVYVIEEGCQAEQQGLNIGDRILDVNGTDFTHLTHAEAVTIMRNAWN 182

Query: 120 ISMRVRFFPYNYHRQKER 137
           + M V+  P +   Q ++
Sbjct: 183 VIMTVQPCPESDSGQGQQ 236
>01502
          Length = 1949

 Score = 40.4 bits (93), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 19/54 (35%), Positives = 32/54 (59%)
 Frame = +1

Query: 71  GIFISKVIPDSDAHRAGLQEGDQVLAVNDVDFQDIEHSKAVEILKTAREISMRV 124
           GI+++ +  +S A R GLQ  D++L +N  DF  + H +AVE ++    + M V
Sbjct: 34  GIYVTFIYENSPAARCGLQLHDKILQLNGKDFTVVTHKQAVENIRKKPVLKMLV 195
>02951
          Length = 1076

 Score = 40.0 bits (92), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 19/54 (35%), Positives = 32/54 (59%)
 Frame = +2

Query: 71  GIFISKVIPDSDAHRAGLQEGDQVLAVNDVDFQDIEHSKAVEILKTAREISMRV 124
           GI+++ +  +S A R GLQ  D++L +N  DF  + H +AVE ++    + M V
Sbjct: 20  GIYVTFIYENSPAARCGLQLHDKILQLNGKDFTVVTHKQAVENIRKKPVLKMLV 181
>29705
          Length = 674

 Score = 38.9 bits (89), Expect = 8e-04,   Method: Compositional matrix adjust.
 Identities = 20/51 (39%), Positives = 33/51 (64%), Gaps = 1/51 (1%)
 Frame = -1

Query: 71  GIFISKVIPDSDAHRAG-LQEGDQVLAVNDVDFQDIEHSKAVEILKTAREI 120
           GIFI+KVI    A + G +   D++LAVN+ + +D+ H +AV  LK+  ++
Sbjct: 362 GIFITKVIEGGSAEQDGRIAVMDRLLAVNEHNLEDVTHEEAVAALKSTGDV 210
>03831
          Length = 1143

 Score = 37.4 bits (85), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 26/82 (31%), Positives = 41/82 (50%), Gaps = 1/82 (1%)
 Frame = +3

Query: 59  GFNIRGGKASQLGIFISKVIPDSDAHRAGLQEGDQVLAVNDVDFQDIEHSKAVEILKTAR 118
           GFN+   K  + G FI KV   S A  AGL+ GD+++ VN  +  +  H + V  +K   
Sbjct: 174 GFNLHAEKG-KAGQFIGKVDEGSPAEAAGLKAGDRIVEVNGTNIGNENHQQVVGRIKAGG 350

Query: 119 -EISMRVRFFPYNYHRQKERTV 139
            E  + V     + H ++E+ V
Sbjct: 351 DETRLLVVDQETDQHYKEEKRV 416
>08480
          Length = 698

 Score = 36.6 bits (83), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 17/47 (36%), Positives = 31/47 (65%), Gaps = 1/47 (2%)
 Frame = -1

Query: 88  LQEGDQVLAVNDVDFQDIEHSKAVEILKTARE-ISMRVRFFPYNYHR 133
           L+ GD++L+VNDVD +   H +A + LK A + + +  ++ P +Y+R
Sbjct: 674 LRRGDKILSVNDVDVERATHEQAAQALKRAGDTVEIIAQYKPEDYNR 534
>26556
          Length = 513

 Score = 35.4 bits (80), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 15/33 (45%), Positives = 24/33 (72%)
 Frame = +2

Query: 92  DQVLAVNDVDFQDIEHSKAVEILKTAREISMRV 124
           D++L VN +DF+ I+H+ AV ILKT+  + + V
Sbjct: 2   DKILQVNHIDFRHIDHNTAVNILKTSATVELLV 100
>26948
          Length = 2380

 Score = 30.8 bits (68), Expect = 0.21,   Method: Composition-based stats.
 Identities = 18/61 (29%), Positives = 33/61 (54%)
 Frame = -2

Query: 36   YNNELTQFLPRIVTLKKPPGAQLGFNIRGGKASQLGIFISKVIPDSDAHRAGLQEGDQVL 95
            +N++     PR V L++ P    GF++RG       + ++ +  DS A R+G++ GD V+
Sbjct: 1629 FNSKNQWAAPRQVVLERLPTEGFGFSVRGDSP----VIVADIELDSVAGRSGMKVGDFVV 1462

Query: 96   A 96
             
Sbjct: 1461 G 1459
>20530
          Length = 431

 Score = 30.0 bits (66), Expect = 0.36,   Method: Compositional matrix adjust.
 Identities = 15/34 (44%), Positives = 22/34 (64%)
 Frame = +1

Query: 72  IFISKVIPDSDAHRAGLQEGDQVLAVNDVDFQDI 105
           +++S+V  +  A  +GLQEGD V+AVN V    I
Sbjct: 19  VYVSQVTNEERA--SGLQEGDIVVAVNGVSCGGI 114
>34468
          Length = 1502

 Score = 28.9 bits (63), Expect = 0.74,   Method: Composition-based stats.
 Identities = 14/43 (32%), Positives = 24/43 (55%)
 Frame = +1

Query: 10  YPVVFLPAYENPPAWIPPHERVYHPDYNNELTQFLPRIVTLKK 52
           Y +  + ++EN PAWI   +R       + LT+++PRI+   K
Sbjct: 736 YDMTKMSSFENMPAWIEECDR-------HNLTKYIPRILVGNK 843
>26154
          Length = 446

 Score = 28.1 bits (61), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 14/39 (35%), Positives = 22/39 (56%), Gaps = 1/39 (2%)
 Frame = -3

Query: 83  AHRAG-LQEGDQVLAVNDVDFQDIEHSKAVEILKTAREI 120
           AHR G +Q GD+++A+NDV         A  +L+   E+
Sbjct: 402 AHRCGSIQAGDKLMAINDVRLDTCTVDDATHLLELPDEL 286
>26680
          Length = 395

 Score = 26.9 bits (58), Expect = 2.9,   Method: Compositional matrix adjust.
 Identities = 12/32 (37%), Positives = 20/32 (62%)
 Frame = +2

Query: 38  NELTQFLPRIVTLKKPPGAQLGFNIRGGKASQ 69
           N+LTQ   ++ T++   G Q+GF+  G K+ Q
Sbjct: 89  NQLTQVTRQVYTIETKQGRQVGFHAWGLKSPQ 184
>13677
          Length = 435

 Score = 25.8 bits (55), Expect = 7.0,   Method: Compositional matrix adjust.
 Identities = 9/20 (45%), Positives = 12/20 (60%)
 Frame = -3

Query: 9   DYPVVFLPAYENPPAWIPPH 28
           D P   LPA++  P W+ PH
Sbjct: 145 DKPYTPLPAHQTAPMWLCPH 86
>00956
          Length = 1953

 Score = 25.4 bits (54), Expect = 8.8,   Method: Compositional matrix adjust.
 Identities = 19/45 (42%), Positives = 24/45 (53%)
 Frame = +1

Query: 46   RIVTLKKPPGAQLGFNIRGGKASQLGIFISKVIPDSDAHRAGLQE 90
            +I T K  PG   GF  RGGKA  L +  + V P    H+A L+E
Sbjct: 1486 KIQTAKVGPGNFGGF--RGGKAQSLHVKQTIVKPSLGQHKAVLRE 1614
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|27370522|ref|NP_766602.1| lysophosphatidylcholine
acyltransferase 2 [Mus musculus]
         (544 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

26019                                                                  61   1e-09
14594                                                                  46   5e-05
07678                                                                  41   0.001
14945                                                                  38   0.011
22063                                                                  37   0.014
33397                                                                  36   0.033
05237                                                                  34   0.16 
08380                                                                  34   0.16 
00167                                                                  33   0.32 
14366                                                                  32   0.52 
03732                                                                  32   0.56 
02929                                                                  30   2.7  
01773                                                                  30   2.8  
30885                                                                  29   3.8  
01019                                                                  29   5.3  
>26019
          Length = 1561

 Score = 60.8 bits (146), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 25/86 (29%), Positives = 54/86 (62%)
 Frame = +2

Query: 377 GRIGIEEFAEYLKLPVSDVLRQLFALFDRNNDGSIDFREYVIGLAVLCNPANTEEIIQVA 436
           G + I+EF    +L  + +++++  +FD + +G +DF+E++ G++      + E  ++ A
Sbjct: 143 GSLSIDEFMSLPELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGISQFSVKGDKESKLRFA 322

Query: 437 FKLFDVDEDGYITEEEFCTILQASLG 462
           FK++D+D+DGYI+  E   +L+  +G
Sbjct: 323 FKIYDMDKDGYISNGELFQVLKMMVG 400
>14594
          Length = 1014

 Score = 45.8 bits (107), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 32/101 (31%), Positives = 55/101 (54%), Gaps = 5/101 (4%)
 Frame = +3

Query: 391 PVSDVLRQLFALFDRNNDGSIDFREYVIGLAVLCNPANTEEIIQVAFKLFDVDEDGYITE 450
           P  + L+ +    D + +G+IDF E++  +A      + EE ++ AF++FD D +GYI+ 
Sbjct: 540 PTENELQDMINEVDADGNGTIDFEEFLHMMARKMKDTDCEEELREAFRVFDKDGNGYISA 719

Query: 451 EEFCTILQASLG--VPDLNVSGLFREIAQRDS---VSYEEF 486
            E   ++  +LG  + D  V  + +E A  D    V+YEEF
Sbjct: 720 AELRHVM-TNLGEKLTDEEVDEMIKE-ADLDGDGMVNYEEF 836

 Score = 39.3 bits (90), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 27/96 (28%), Positives = 44/96 (45%), Gaps = 8/96 (8%)
 Frame = +3

Query: 372 SSSKGGRIGIEEFAEYLKLPVSDV-----LRQLFALFDRNNDGSI---DFREYVIGLAVL 423
            +   G I  EEF   +   + D      LR+ F +FD++ +G I   + R  +  L   
Sbjct: 579 DADGNGTIDFEEFLHMMARKMKDTDCEEELREAFRVFDKDGNGYISAAELRHVMTNLGEK 758

Query: 424 CNPANTEEIIQVAFKLFDVDEDGYITEEEFCTILQA 459
                 +E+I+ A    D+D DG +  EEF T++ A
Sbjct: 759 LTDEEVDEMIKEA----DLDGDGMVNYEEFVTMMTA 854
>07678
          Length = 958

 Score = 41.2 bits (95), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 28/99 (28%), Positives = 52/99 (52%)
 Frame = +1

Query: 362 KHLDEYASIASSSKGGRIGIEEFAEYLKLPVSDVLRQLFALFDRNNDGSIDFREYVIGLA 421
           K +D+  + +   K  + GI EF   L     DV++++F  FD++  G+IDF E+++ L 
Sbjct: 340 KIMDDDGNRSLDFKEFKKGITEFG--LTQFEGDVIQEMFTCFDKDZSGTIDFDEFLVKLR 513

Query: 422 VLCNPANTEEIIQVAFKLFDVDEDGYITEEEFCTILQAS 460
              +    +++IQ AF+  D   DG +T E+   +   +
Sbjct: 514 PPMSQMR-KDLIQRAFQKLDKTGDGVVTVEDLKGVYNVT 627

 Score = 31.2 bits (69), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 26/89 (29%), Positives = 42/89 (47%), Gaps = 12/89 (13%)
 Frame = +1

Query: 377 GRIGIEEFAEYLKLPVS----DVLRQLFALFDRNNDGSIDFREYVIGLAVLCNPA----- 427
           G I  +EF   L+ P+S    D++++ F   D+  DG +   +      V  +P      
Sbjct: 475 GTIDFDEFLVKLRPPMSQMRKDLIQRAFQKLDKTGDGVVTVEDLKGVYNVTKHPKYLNGE 654

Query: 428 -NTEEIIQVAFKLFDV--DEDGYITEEEF 453
              E I+++    FD   D+DG IT+EEF
Sbjct: 655 WTEERILRIFLDSFDSPNDKDGKITKEEF 741
>14945
          Length = 1337

 Score = 37.7 bits (86), Expect = 0.011,   Method: Compositional matrix adjust.
 Identities = 17/56 (30%), Positives = 32/56 (57%)
 Frame = +1

Query: 391 PVSDVLRQLFALFDRNNDGSIDFREYVIGLAVLCNPANTEEIIQVAFKLFDVDEDG 446
           P  + ++++ A  D+   G+IDF +++  +    +  + +E I  AF+LFD DE G
Sbjct: 211 PKKEEIKKMIAEIDKEGTGTIDFNDFLTIMTQKMSEKDAKEEILKAFRLFDDDETG 378

 Score = 33.1 bits (74), Expect = 0.30,   Method: Compositional matrix adjust.
 Identities = 20/70 (28%), Positives = 35/70 (50%)
 Frame = +1

Query: 396 LRQLFALFDRNNDGSIDFREYVIGLAVLCNPANTEEIIQVAFKLFDVDEDGYITEEEFCT 455
           +R+ F LFD +  G+ID +E  + +  L      EEI ++  ++ D +  G I   +F T
Sbjct: 118 IREAFDLFDADGSGTIDAKELKVAMRALGFEPKKEEIKKMIAEI-DKEGTGTIDFNDFLT 294

Query: 456 ILQASLGVPD 465
           I+   +   D
Sbjct: 295 IMTQKMSEKD 324
>22063
          Length = 688

 Score = 37.4 bits (85), Expect = 0.014,   Method: Compositional matrix adjust.
 Identities = 17/56 (30%), Positives = 32/56 (57%)
 Frame = +3

Query: 391 PVSDVLRQLFALFDRNNDGSIDFREYVIGLAVLCNPANTEEIIQVAFKLFDVDEDG 446
           P  + ++++ A  D+   G+IDF +++  +    +  + +E I  AF+LFD DE G
Sbjct: 270 PKKEEIKKMIAEIDKEGTGTIDFNDFLTIMTQKMSEKDAKEEILKAFRLFDDDETG 437

 Score = 32.7 bits (73), Expect = 0.41,   Method: Compositional matrix adjust.
 Identities = 20/70 (28%), Positives = 35/70 (50%)
 Frame = +3

Query: 396 LRQLFALFDRNNDGSIDFREYVIGLAVLCNPANTEEIIQVAFKLFDVDEDGYITEEEFCT 455
           +R+ F LFD +  G+ID +E  + +  L      EEI ++  ++ D +  G I   +F T
Sbjct: 177 IREAFDLFDADGSGTIDAKELKVAMRALGFEPKKEEIKKMIAEI-DKEGTGTIDFNDFLT 353

Query: 456 ILQASLGVPD 465
           I+   +   D
Sbjct: 354 IMTQKMSEKD 383
>33397
          Length = 1723

 Score = 36.2 bits (82), Expect = 0.033,   Method: Compositional matrix adjust.
 Identities = 19/48 (39%), Positives = 27/48 (56%)
 Frame = +3

Query: 409 GSIDFREYVIGLAVLCNPANTEEIIQVAFKLFDVDEDGYITEEEFCTI 456
           G I F +Y+  L VL  P    EI   AF++FD++ DG +  EEF  +
Sbjct: 135 GLISFSDYIFLLTVLSTPPRNFEI---AFRMFDINGDGELDLEEFNRV 269

 Score = 33.5 bits (75), Expect = 0.24,   Method: Compositional matrix adjust.
 Identities = 19/50 (38%), Positives = 30/50 (60%), Gaps = 1/50 (2%)
 Frame = +2

Query: 410 SIDFREYVIGLAVLCNPAN-TEEIIQVAFKLFDVDEDGYITEEEFCTILQ 458
           SID RE    +A     A+ TE +I V F LFD + DG ++ +EF ++++
Sbjct: 701 SID-RETFHHVAKTVAMADLTEHVIDVVFTLFDENNDGELSNKEFVSVMK 847

 Score = 28.5 bits (62), Expect = 7.8,   Method: Compositional matrix adjust.
 Identities = 11/23 (47%), Positives = 16/23 (69%)
 Frame = +2

Query: 395 VLRQLFALFDRNNDGSIDFREYV 417
           V+  +F LFD NNDG +  +E+V
Sbjct: 767 VIDVVFTLFDENNDGELSNKEFV 835
>05237
          Length = 472

 Score = 33.9 bits (76), Expect = 0.16,   Method: Composition-based stats.
 Identities = 20/67 (29%), Positives = 34/67 (50%), Gaps = 3/67 (4%)
 Frame = +3

Query: 394 DVLRQLFALFDRNNDGSI---DFREYVIGLAVLCNPANTEEIIQVAFKLFDVDEDGYITE 450
           D LR+ F +FD++ +G I   + R  +  L         +E+I+ A    D+D DG +  
Sbjct: 27  DELREAFRVFDKDGNGFISASELRHVMTNLGEKLTDEEVDEMIREA----DIDGDGQVNY 194

Query: 451 EEFCTIL 457
           EEF  ++
Sbjct: 195 EEFVKMM 215

 Score = 32.3 bits (72), Expect = 0.47,   Method: Composition-based stats.
 Identities = 21/63 (33%), Positives = 37/63 (58%), Gaps = 4/63 (6%)
 Frame = +3

Query: 428 NTEEIIQVAFKLFDVDEDGYITEEEFCTILQASLG--VPDLNVSGLFRE--IAQRDSVSY 483
           +T++ ++ AF++FD D +G+I+  E   ++  +LG  + D  V  + RE  I     V+Y
Sbjct: 18  DTDDELREAFRVFDKDGNGFISASELRHVM-TNLGEKLTDEEVDEMIREADIDGDGQVNY 194

Query: 484 EEF 486
           EEF
Sbjct: 195 EEF 203
>08380
          Length = 1236

 Score = 33.9 bits (76), Expect = 0.16,   Method: Compositional matrix adjust.
 Identities = 28/132 (21%), Positives = 51/132 (38%), Gaps = 31/132 (23%)
 Frame = -1

Query: 372 SSSKGGRIGIEEFAEYLKLPVSDVL-------RQLFALFDRNNDGSIDFREYVIGL---- 420
            S K G++ + E   ++K  + +          ++F   D +N+G + ++EY +      
Sbjct: 855 DSDKDGKLSVAELEAWVKDKMEEHFSEATQENEEIFKHLDPDNNGKVHWKEYYVHFLLAK 676

Query: 421 ---------------AVLCNPANTEEIIQVAFKLFDVDE---DGYITEEEFCTILQASLG 462
                           +  +P   EEII+  F+  D D    D  +T EEF +       
Sbjct: 675 GYKQDVASRHVVDYDZIQLDPDAKEEIIRYKFRWSDADGEPMDNELTREEFMSFRHPEQS 496

Query: 463 VPDLN--VSGLF 472
              LN  V+G+ 
Sbjct: 495 EKTLNNMVNGIL 460
>00167
          Length = 2176

 Score = 33.1 bits (74), Expect = 0.32,   Method: Compositional matrix adjust.
 Identities = 18/60 (30%), Positives = 34/60 (56%)
 Frame = +3

Query: 393 SDVLRQLFALFDRNNDGSIDFREYVIGLAVLCNPANTEEIIQVAFKLFDVDEDGYITEEE 452
           S+ L ++F  FD++  G++DF E+++ L    N     ++++ AF   D   DG IT ++
Sbjct: 837 SEELNEVFRRFDKDGTGTLDFEEFLLALRPKMNEFR-RKLVKKAFAKMDKTGDGIITADD 1013
>14366
          Length = 499

 Score = 32.3 bits (72), Expect = 0.52,   Method: Composition-based stats.
 Identities = 19/69 (27%), Positives = 36/69 (52%)
 Frame = -3

Query: 393 SDVLRQLFALFDRNNDGSIDFREYVIGLAVLCNPANTEEIIQVAFKLFDVDEDGYITEEE 452
           SD LR+ F +FD+  +G I+  E    L  L    + EE+ ++  +  D+  DG ++  +
Sbjct: 254 SDNLREAFRIFDKEGNGMINAAELRHVLTHLGEKLSDEEVDEM-IREADISGDGQVSYND 78

Query: 453 FCTILQASL 461
           F  +++  L
Sbjct: 77  FVKVMENGL 51
>03732
          Length = 1114

 Score = 32.3 bits (72), Expect = 0.56,   Method: Compositional matrix adjust.
 Identities = 33/118 (27%), Positives = 48/118 (40%), Gaps = 6/118 (5%)
 Frame = -1

Query: 375 KGGRIGIEEFAEYLKLPVSDVLRQLFALFDRNNDGSIDFREYVIGLAVLCNPANTEEIIQ 434
             G I  +EF    K  V+D  +  F  +DR+N GSID  E    L        ++    
Sbjct: 952 NSGTINFQEFQALWKY-VTD-WQNCFRSYDRDNSGSIDRNELKNALTGFGYRL-SDRFFD 782

Query: 435 VAFKLFDVDEDGYITEEEF---CTILQ---ASLGVPDLNVSGLFREIAQRDSVSYEEF 486
           V  K FD    G +  ++F   C +LQ    S    D +  G  +       +SYE+F
Sbjct: 781 VLVKKFDRQGKGTVAFDDFIQCCVVLQTLTTSFRTHDQDQDGWIQ-------ISYEQF 629
>02929
          Length = 1353

 Score = 30.0 bits (66), Expect = 2.7,   Method: Compositional matrix adjust.
 Identities = 20/59 (33%), Positives = 32/59 (54%), Gaps = 3/59 (5%)
 Frame = +2

Query: 437 FKLFDVDEDGYITEEEFCT-ILQASLGVPDLNVSGLFREIAQRDSVSYEEFKSF--ALK 492
           F+  D D DG++TEEEF   ++Q+        ++ +F +I  R+     E+K F  ALK
Sbjct: 194 FRRQDKDGDGFLTEEEFVNGMMQSRFPTNRTELNAVF-DIFDREKRGLIEYKDFVDALK 367
>01773
          Length = 1950

 Score = 30.0 bits (66), Expect = 2.8,   Method: Compositional matrix adjust.
 Identities = 23/68 (33%), Positives = 33/68 (48%), Gaps = 1/68 (1%)
 Frame = +1

Query: 391 PVSDVLRQLFALFDRNNDGSIDFREYVIGLAVLCNPANTEEIIQVAFKLFDV-DEDGYIT 449
           P +D  +QLF   D+NNDG ++ +E +  L      + ++  I   F  FD    D  IT
Sbjct: 145 PNTDAYKQLFKEADKNNDGYLEIKE-LRELFKRNGSSLSDSQIADTFVFFDGPRGDKRIT 321

Query: 450 EEEFCTIL 457
            E FC  L
Sbjct: 322 FEXFCKGL 345
>30885
          Length = 1090

 Score = 29.3 bits (64), Expect = 3.8,   Method: Compositional matrix adjust.
 Identities = 14/47 (29%), Positives = 28/47 (59%)
 Frame = -1

Query: 395 VLRQLFALFDRNNDGSIDFREYVIGLAVLCNPANTEEIIQVAFKLFD 441
           +L+ +F  FDR+N+G I   ++  GL +L  P +T E+  +  + ++
Sbjct: 796 LLKPVFQDFDRHNNGHITRVQFSQGLTMLEIPISTPELAALEARFYN 656
>01019
          Length = 1705

 Score = 28.9 bits (63), Expect = 5.3,   Method: Compositional matrix adjust.
 Identities = 21/75 (28%), Positives = 36/75 (48%), Gaps = 4/75 (5%)
 Frame = +1

Query: 402 LFDRNNDGSI---DFREYVIGLAVLCNPANTEEIIQVAFKLFDVDEDGYITEEEFCTILQ 458
           +FD++ +G I   + R  +  L         +E+I+ A    D+D DG +  EEF T++ 
Sbjct: 43  VFDKDGNGFISAAELRHVMTNLGEKLTDEEVDEMIREA----DIDGDGQVNYEEFVTMMT 210

Query: 459 ASLGVPDLN-VSGLF 472
           +   V   +   GLF
Sbjct: 211 SK*AVQSAHGARGLF 255
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|27923929|ref|NP_778163.1| hippocalcin-like 4 [Mus
musculus]
         (191 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

26019                                                                  59   1e-09
07678                                                                  42   2e-04
14594                                                                  41   3e-04
00167                                                                  39   0.001
07198                                                                  37   0.005
14366                                                                  37   0.006
38338                                                                  34   0.033
17484                                                                  33   0.066
15966                                                                  32   0.11 
05237                                                                  32   0.11 
26610                                                                  32   0.12 
03732                                                                  30   0.66 
13551                                                                  30   0.82 
18571                                                                  30   0.88 
27864                                                                  29   1.2  
09410                                                                  29   1.3  
33397                                                                  29   1.4  
08380                                                                  29   1.4  
39823                                                                  29   1.4  
01773                                                                  28   1.7  
02929                                                                  28   2.0  
26849                                                                  28   2.1  
12214                                                                  27   5.1  
12128                                                                  27   7.2  
03616                                                                  26   7.8  
35179                                                                  26   8.6  
>26019
          Length = 1561

 Score = 59.3 bits (142), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 34/96 (35%), Positives = 55/96 (57%), Gaps = 1/96 (1%)
 Frame = +2

Query: 40  SGILNLEEFQQLYIKFFPYGDASKFAQHAFRTFDKNGDGTIDFREFICALS-VTSRGSFE 98
           SG L+++EF  L     P    +   Q     FD +G+G +DF+EFI  +S  + +G  E
Sbjct: 140 SGSLSIDEFMSL-----PELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGISQFSVKGDKE 304

Query: 99  QKLNWAFEMYDLDGDGRITRLEMLEIIEAIYKMVGT 134
            KL +AF++YD+D DG I+  E+ ++++    MVG 
Sbjct: 305 SKLRFAFKIYDMDKDGYISNGELFQVLKM---MVGN 403
>07678
          Length = 958

 Score = 41.6 bits (96), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 38/132 (28%), Positives = 61/132 (46%), Gaps = 3/132 (2%)
 Frame = +1

Query: 43  LNLEEFQQLYIKFFPYGDASKFAQHAFRTFDKNGDGTIDFREFICALSVTSRGSFEQKLN 102
           L+ +EF++   +F          Q  F  FDK+  GTIDF EF+  L        +  + 
Sbjct: 370 LDFKEFKKGITEFGLTQFEGDVIQEMFTCFDKDZSGTIDFDEFLVKLRPPMSQMRKDLIQ 549

Query: 103 WAFEMYDLDGDGRITRLEMLEIIEAIYKMVGTVIMMRMNQDGLTPQQRVDKIFK---KMD 159
            AF+  D  GDG +T    +E ++ +Y +      +    +G   ++R+ +IF       
Sbjct: 550 RAFQKLDKTGDGVVT----VEDLKGVYNVTKHPKYL----NGEWTEERILRIFLDSFDSP 705

Query: 160 QDKDDQITLEEF 171
            DKD +IT EEF
Sbjct: 706 NDKDGKITKEEF 741

 Score = 27.3 bits (59), Expect = 3.6,   Method: Compositional matrix adjust.
 Identities = 25/105 (23%), Positives = 48/105 (45%), Gaps = 1/105 (0%)
 Frame = +1

Query: 69  FRTFDKNGDGTIDFREFICALSVTSRGSFEQK-LNWAFEMYDLDGDGRITRLEMLEIIEA 127
           F+  D +G+ ++DF+EF   ++      FE   +   F  +D D  G I      +  E 
Sbjct: 337 FKIMDDDGNRSLDFKEFKKGITEFGLTQFEGDVIQEMFTCFDKDZSGTI------DFDEF 498

Query: 128 IYKMVGTVIMMRMNQDGLTPQQRVDKIFKKMDQDKDDQITLEEFK 172
           + K+   +  MR        +  + + F+K+D+  D  +T+E+ K
Sbjct: 499 LVKLRPPMSQMR--------KDLIQRAFQKLDKTGDGVVTVEDLK 609
>14594
          Length = 1014

 Score = 40.8 bits (94), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 31/116 (26%), Positives = 55/116 (47%)
 Frame = +3

Query: 12  VLEDLVQNTEFSEQELKQWYKGFLKDCPSGILNLEEFQQLYIKFFPYGDASKFAQHAFRT 71
           V+  L QN   +E EL+        D  +G ++ EEF  +  +     D  +  + AFR 
Sbjct: 516 VMRSLGQNP--TENELQDMINEVDAD-GNGTIDFEEFLHMMARKMKDTDCEEELREAFRV 686

Query: 72  FDKNGDGTIDFREFICALSVTSRGSFEQKLNWAFEMYDLDGDGRITRLEMLEIIEA 127
           FDK+G+G I   E    ++       +++++   +  DLDGDG +   E + ++ A
Sbjct: 687 FDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIKEADLDGDGMVNYEEFVTMMTA 854

 Score = 35.4 bits (80), Expect = 0.013,   Method: Compositional matrix adjust.
 Identities = 33/143 (23%), Positives = 57/143 (39%), Gaps = 37/143 (25%)
 Frame = +3

Query: 66  QHAFRTFDKNGD------------------------------------GTIDFREFICAL 89
           + AF  FDK+GD                                    GTIDF EF+  +
Sbjct: 450 KEAFSLFDKDGDGTITTSELGTVMRSLGQNPTENELQDMINEVDADGNGTIDFEEFLHMM 629

Query: 90  SVTSRGS-FEQKLNWAFEMYDLDGDGRITRLEMLEIIEAIYKMVGTVIMMRMNQDGLTPQ 148
           +   + +  E++L  AF ++D DG+G I+  E+  ++  + + +                
Sbjct: 630 ARKMKDTDCEEELREAFRVFDKDGNGYISAAELRHVMTNLGEKL--------------TD 767

Query: 149 QRVDKIFKKMDQDKDDQITLEEF 171
           + VD++ K+ D D D  +  EEF
Sbjct: 768 EEVDEMIKEADLDGDGMVNYEEF 836
>00167
          Length = 2176

 Score = 39.3 bits (90), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 25/53 (47%), Positives = 29/53 (54%), Gaps = 1/53 (1%)
 Frame = +3

Query: 66  QHAFRTFDKNGDGTIDFREFICALSVTSRGSFEQKL-NWAFEMYDLDGDGRIT 117
              FR FDK+G GT+DF EF+ AL       F +KL   AF   D  GDG IT
Sbjct: 849 NEVFRRFDKDGTGTLDFEEFLLALR-PKMNEFRRKLVKKAFAKMDKTGDGIIT 1004
>07198
          Length = 1675

 Score = 37.0 bits (84), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 38/128 (29%), Positives = 59/128 (46%), Gaps = 8/128 (6%)
 Frame = -3

Query: 41  GILNLEEFQQLYI-KFFPYGDASKFAQHAFRTFDKNGDGTIDFREFIC-ALSVTSRGSFE 98
           G LN +E+   ++   FP  +  +F     R  DKN DGTI   EF+    +  +R S E
Sbjct: 437 GSLNSKEYFAFFMPNSFPQLELERF----MRQSDKNKDGTISMEEFMPEGATGDTRTSSE 270

Query: 99  QKLNWAFEMYDLDGDGRITRLEMLEII------EAIYKMVGTVIMMRMNQDGLTPQQRVD 152
           +    +F+ YD D DG ++  E +E I       A  ++     +  +N DG   +   D
Sbjct: 269 E----SFKNYDKDKDGSLSLEEAMEWINPSSDEHADVEVEHLFTIGDVNHDGKLSK---D 111

Query: 153 KIFKKMDQ 160
           +I  K DQ
Sbjct: 110 EILNKADQ 87

 Score = 26.6 bits (57), Expect = 6.5,   Method: Compositional matrix adjust.
 Identities = 15/40 (37%), Positives = 22/40 (55%), Gaps = 2/40 (5%)
 Frame = -3

Query: 133 GTVIMMRMNQDGLTPQQRV--DKIFKKMDQDKDDQITLEE 170
           GT+ M     +G T   R   ++ FK  D+DKD  ++LEE
Sbjct: 335 GTISMEEFMPEGATGDTRTSSEESFKNYDKDKDGSLSLEE 216
>14366
          Length = 499

 Score = 36.6 bits (83), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 21/84 (25%), Positives = 43/84 (51%)
 Frame = -3

Query: 43  LNLEEFQQLYIKFFPYGDASKFAQHAFRTFDKNGDGTIDFREFICALSVTSRGSFEQKLN 102
           L L+E   +  K+    + S   + AFR FDK G+G I+  E    L+       +++++
Sbjct: 311 LTLQEVIAIVTKYEFAPETSDNLREAFRIFDKEGNGMINAAELRHVLTHLGEKLSDEEVD 132

Query: 103 WAFEMYDLDGDGRITRLEMLEIIE 126
                 D+ GDG+++  + ++++E
Sbjct: 131 EMIREADISGDGQVSYNDFVKVME 60
>38338
          Length = 463

 Score = 34.3 bits (77), Expect = 0.033,   Method: Compositional matrix adjust.
 Identities = 18/49 (36%), Positives = 24/49 (48%)
 Frame = -2

Query: 68  AFRTFDKNGDGTIDFREFICALSVTSRGSFEQKLNWAFEMYDLDGDGRI 116
           AF  FDK+GDGTI  +E    +    +   E +L       D DG+G I
Sbjct: 153 AFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTI 7
>17484
          Length = 471

 Score = 33.1 bits (74), Expect = 0.066,   Method: Compositional matrix adjust.
 Identities = 25/82 (30%), Positives = 37/82 (45%), Gaps = 1/82 (1%)
 Frame = -3

Query: 45  LEEFQQLYIKFFPYG-DASKFAQHAFRTFDKNGDGTIDFREFICALSVTSRGSFEQKLNW 103
           +EEF  L +     G +  K  + AFR FD+NGDG I   E   A++   +   +  +  
Sbjct: 328 VEEFLPLIVGRMKGGSEKDKEMRDAFRAFDQNGDGVISISELRQAMAKMGQKLSDADVES 149

Query: 104 AFEMYDLDGDGRITRLEMLEII 125
                D DGDG +   E  + I
Sbjct: 148 IIRDVDKDGDGFVNYEEFTKFI 83
>15966
          Length = 362

 Score = 32.3 bits (72), Expect = 0.11,   Method: Compositional matrix adjust.
 Identities = 33/117 (28%), Positives = 51/117 (43%), Gaps = 1/117 (0%)
 Frame = +2

Query: 60  DASKFAQHA-FRTFDKNGDGTIDFREFICALSVTSRGSFEQKLNWAFEMYDLDGDGRITR 118
           D S+ ++HA F      GD  I F EF   L       F QKL   F+  D  GDG + R
Sbjct: 20  DESRRSRHARFFVVPSCGDKRITFEEFCKGLDQIVM--FVQKLAELFKAKDKSGDGYLDR 193

Query: 119 LEMLEIIEAIYKMVGTVIMMRMNQDGLTPQQRVDKIFKKMDQDKDDQITLEEFKEAA 175
            E+  +++   +        +   D ++       I K  D++ D++I  EEF +A 
Sbjct: 194 DELKALLDESGQ--------KFTADDVSA------ILKSADKNNDNKICFEEFVDAC 322
>05237
          Length = 472

 Score = 32.3 bits (72), Expect = 0.11,   Method: Compositional matrix adjust.
 Identities = 16/60 (26%), Positives = 33/60 (55%)
 Frame = +3

Query: 66  QHAFRTFDKNGDGTIDFREFICALSVTSRGSFEQKLNWAFEMYDLDGDGRITRLEMLEII 125
           + AFR FDK+G+G I   E    ++       +++++      D+DGDG++   E ++++
Sbjct: 36  REAFRVFDKDGNGFISASELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVKMM 215
>26610
          Length = 455

 Score = 32.3 bits (72), Expect = 0.12,   Method: Compositional matrix adjust.
 Identities = 18/64 (28%), Positives = 36/64 (56%), Gaps = 1/64 (1%)
 Frame = +3

Query: 90  SVTSRGSFEQKLNWAFEMYDLDGDGRITRLEMLEIIEAIYKMVGTVIMMR-MNQDGLTPQ 148
           S++   S +  ++ AFE++D D DG+I   E+   I ++  +V    + R +++ G+ P 
Sbjct: 15  SLSPTMSSKDAVSEAFELFDTDNDGKIAASEVGTAIRSLGHVVTDSDLRRLLSKAGIEPH 194

Query: 149 QRVD 152
            +VD
Sbjct: 195 GKVD 206
>03732
          Length = 1114

 Score = 30.0 bits (66), Expect = 0.66,   Method: Compositional matrix adjust.
 Identities = 38/156 (24%), Positives = 64/156 (41%), Gaps = 24/156 (15%)
 Frame = -1

Query: 40   SGILNLEEFQQLYIKFFPYGDASKFAQHAFR----TFDKNGDGTIDFREFICALSVTSRG 95
            SG +++ E QQ        G  + F     R     FD++  GTI+F+EF        + 
Sbjct: 1060 SGNISVNELQQA----LSNGTWTPFNPETVRLMIGMFDRDNSGTINFQEF--------QA 917

Query: 96   SFEQKLNW--AFEMYDLDGDGRITRLEMLEIIEAI-YKMVGT---VIMMRMNQDG----- 144
             ++   +W   F  YD D  G I R E+   +    Y++      V++ + ++ G     
Sbjct: 916  LWKYVTDWQNCFRSYDRDNSGSIDRNELKNALTGFGYRLSDRFFDVLVKKFDRQGKGTVA 737

Query: 145  -------LTPQQRVDKIFKKMDQDKDD--QITLEEF 171
                       Q +   F+  DQD+D   QI+ E+F
Sbjct: 736  FDDFIQCCVVLQTLTTSFRTHDQDQDGWIQISYEQF 629
>13551
          Length = 529

 Score = 29.6 bits (65), Expect = 0.82,   Method: Compositional matrix adjust.
 Identities = 31/110 (28%), Positives = 49/110 (44%), Gaps = 7/110 (6%)
 Frame = +1

Query: 69  FRTFDKNGDGTIDFREFICALSVTSRGSFEQK-------LNWAFEMYDLDGDGRITRLEM 121
            R  DKN DG +DF EF CAL    R   +++       +N  F      GD  I+  +M
Sbjct: 94  LREEDKNVDGCLDFEEF-CALYKKKRQKEDKRKEELLMSVNQLFPSSQ-SGDDTISLDKM 267

Query: 122 LEIIEAIYKMVGTVIMMRMNQDGLTPQQRVDKIFKKMDQDKDDQITLEEF 171
             +++ +  M G      M    LT    +D I  K++++ D+ I+  E 
Sbjct: 268 AGLLKQMNNMPGLCSEATM---ALTDTD-IDSIIGKINRNNDNTISKSEL 405
>18571
          Length = 821

 Score = 29.6 bits (65), Expect = 0.88,   Method: Compositional matrix adjust.
 Identities = 14/36 (38%), Positives = 18/36 (50%)
 Frame = -1

Query: 155 FKKMDQDKDDQITLEEFKEAAKSDPSIVLLLQCDMQ 190
           F    Q+   +  +      A +DPSIV LLQCD Q
Sbjct: 812 FPPDGQEPRRETVVGRVHRGAMNDPSIVRLLQCDPQ 705
>27864
          Length = 343

 Score = 28.9 bits (63), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 25/88 (28%), Positives = 36/88 (40%), Gaps = 6/88 (6%)
 Frame = +1

Query: 40  SGILNLEEFQQLYIKFFPYGDASKFAQHAFR----TFDKNGDGTIDFREFICALSVTSRG 95
           SG +++ E QQ        G  + F     R     FD++  GTI+F+EF       +  
Sbjct: 55  SGNISVNELQQA----LSNGTWTPFNPETVRLMIGMFDRDNSGTINFQEFQALWKYVT-- 216

Query: 96  SFEQKLNW--AFEMYDLDGDGRITRLEM 121
                 +W   F  YD D  G I R E+
Sbjct: 217 ------DWQNCFRSYDRDNSGSIDRNEL 282
>09410
          Length = 1079

 Score = 28.9 bits (63), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 17/48 (35%), Positives = 23/48 (47%)
 Frame = -1

Query: 15  DLVQNTEFSEQELKQWYKGFLKDCPSGILNLEEFQQLYIKFFPYGDAS 62
            LV N  F  +   QW+K  L+   S  +NL    Q Y+  F YG+ S
Sbjct: 557 HLVINRLFFLE*RSQWHKTXLESISSYXINLVXLDQDYVICFLYGETS 414
>33397
          Length = 1723

 Score = 28.9 bits (63), Expect = 1.4,   Method: Compositional matrix adjust.
 Identities = 12/18 (66%), Positives = 13/18 (72%)
 Frame = +3

Query: 68  AFRTFDKNGDGTIDFREF 85
           AFR FD NGDG +D  EF
Sbjct: 207 AFRMFDINGDGELDLEEF 260

 Score = 28.9 bits (63), Expect = 1.4,   Method: Compositional matrix adjust.
 Identities = 14/39 (35%), Positives = 23/39 (58%)
 Frame = +3

Query: 78  GTIDFREFICALSVTSRGSFEQKLNWAFEMYDLDGDGRI 116
           G I F ++I  L+V S  +  +    AF M+D++GDG +
Sbjct: 135 GLISFSDYIFLLTVLS--TPPRNFEIAFRMFDINGDGEL 245
>08380
          Length = 1236

 Score = 28.9 bits (63), Expect = 1.4,   Method: Compositional matrix adjust.
 Identities = 25/95 (26%), Positives = 40/95 (42%), Gaps = 15/95 (15%)
 Frame = -1

Query: 72  FDKNGDGTIDFREFICALSVTSRGSFEQKLN--WAFE-------MYDLDGDGRITRLEML 122
            D NGDG +   EF         G   Q ++  W  E         DLD DG++T+ E+ 
Sbjct: 453 IDTNGDGVVTEEEFSALPPGEVEGEEYQAMDKQWQKERQEEFRTAIDLDHDGKVTKDEIK 274

Query: 123 EI------IEAIYKMVGTVIMMRMNQDGLTPQQRV 151
           +       ++A+ +    V  M  ++DG+  Q  V
Sbjct: 273 KYMDPRNPLQALLEAKSLVSYMDDDKDGMISQAEV 169
>39823
          Length = 655

 Score = 28.9 bits (63), Expect = 1.4,   Method: Compositional matrix adjust.
 Identities = 9/22 (40%), Positives = 19/22 (86%)
 Frame = +3

Query: 153 KIFKKMDQDKDDQITLEEFKEA 174
           ++F + D+D+D+Q+T EE+++A
Sbjct: 69  QVFDEFDKDRDNQVTWEEYRDA 134
>01773
          Length = 1950

 Score = 28.5 bits (62), Expect = 1.7,   Method: Compositional matrix adjust.
 Identities = 38/136 (27%), Positives = 56/136 (41%), Gaps = 2/136 (1%)
 Frame = +1

Query: 41  GILNLEEFQQLYIKFFPYGDASKFAQHAFRTFD-KNGDGTIDFREFICALSVTSRGSFEQ 99
           G L ++E ++L+ +       S+ A   F  FD   GD  I F  F   L       F Q
Sbjct: 199 GYLEIKELRELFKRNGSSLSDSQIAD-TFVFFDGPRGDKRITFEXFCKGLDQIVM--FVQ 369

Query: 100 KLNWAFEMYDLDGDGRITRLEMLEII-EAIYKMVGTVIMMRMNQDGLTPQQRVDKIFKKM 158
           KL   F+  D  GDG + R E+  ++ E+  K                    V  I K  
Sbjct: 370 KLAELFKAKDKSGDGYLDRDELKALLDESGQKFTA---------------DDVSAILKSA 504

Query: 159 DQDKDDQITLEEFKEA 174
           D++ D++I  EEF +A
Sbjct: 505 DKNNDNKICFEEFVDA 552
>02929
          Length = 1353

 Score = 28.1 bits (61), Expect = 2.0,   Method: Compositional matrix adjust.
 Identities = 22/83 (26%), Positives = 41/83 (49%), Gaps = 1/83 (1%)
 Frame = +2

Query: 47  EFQQLYIKFFPYGDASKF-AQHAFRTFDKNGDGTIDFREFICALSVTSRGSFEQKLNWAF 105
           +F+    K+  +  A KF     FR  DK+GDG +   EF+  +  +   +   +LN  F
Sbjct: 125 DFESWRGKYLKWIQAKKFRVTDFFRRQDKDGDGFLTEEEFVNGMMQSRFPTNRTELNAVF 304

Query: 106 EMYDLDGDGRITRLEMLEIIEAI 128
           +++D +  G I   E  + ++A+
Sbjct: 305 DIFDREKRGLI---EYKDFVDAL 364
>26849
          Length = 649

 Score = 28.1 bits (61), Expect = 2.1,   Method: Compositional matrix adjust.
 Identities = 16/54 (29%), Positives = 31/54 (57%)
 Frame = +2

Query: 40  SGILNLEEFQQLYIKFFPYGDASKFAQHAFRTFDKNGDGTIDFREFICALSVTS 93
           S +L+LEEF++  +      + +      +R FD +G+GTI+  EF+  ++ T+
Sbjct: 209 SKVLSLEEFKKGILDMHIDINEADIEDMFYR-FDNDGNGTINMTEFLLKVASTN 367
>12214
          Length = 654

 Score = 26.9 bits (58), Expect = 5.1,   Method: Compositional matrix adjust.
 Identities = 27/104 (25%), Positives = 42/104 (40%)
 Frame = -3

Query: 72  FDKNGDGTIDFREFICALSVTSRGSFEQKLNWAFEMYDLDGDGRITRLEMLEIIEAIYKM 131
           FD++  GTID  EF       S   + Q+    FE YD +  G I   E+    +A Y+ 
Sbjct: 628 FDRDMSGTIDINEF------QSLWQYIQQWRSTFERYDSNRSGSIEGNEL----QAAYQQ 479

Query: 132 VGTVIMMRMNQDGLTPQQRVDKIFKKMDQDKDDQITLEEFKEAA 175
           +G  +  R           V  +  K D      +TL+ F ++ 
Sbjct: 478 MGFNVSPRF----------VQTVLYKFDHFGRRSLTLDNFIQSC 377
>12128
          Length = 1429

 Score = 26.6 bits (57), Expect = 7.2,   Method: Compositional matrix adjust.
 Identities = 18/58 (31%), Positives = 26/58 (44%)
 Frame = -2

Query: 134  TVIMMRMNQDGLTPQQRVDKIFKKMDQDKDDQITLEEFKEAAKSDPSIVLLLQCDMQK 191
            T I     +DGLTP Q +  +       KD  +T+ + K     DP   L+ +C  QK
Sbjct: 1206 TCITSSQTEDGLTPSQEICPLSYNCSXQKDFLLTISKAK-----DP---LIHKCSSQK 1057
>03616
          Length = 2372

 Score = 26.2 bits (56), Expect = 7.8,   Method: Compositional matrix adjust.
 Identities = 14/53 (26%), Positives = 28/53 (52%), Gaps = 7/53 (13%)
 Frame = +2

Query: 144 GLTPQQRVDKIFKKMDQDKDDQITLEEFKEAAKS-------DPSIVLLLQCDM 189
            +T + RVD++F + D+D+   I++E  ++  +        D  + L+ QC M
Sbjct: 866 AITDKSRVDEMFLRYDRDRTGYISVENMRDLCRRLQLPVDDDVILALVQQCTM 1024
>35179
          Length = 1860

 Score = 26.2 bits (56), Expect = 8.6,   Method: Compositional matrix adjust.
 Identities = 17/56 (30%), Positives = 30/56 (53%), Gaps = 2/56 (3%)
 Frame = +2

Query: 3   KNNSKLAPEVLEDLVQNTEFSEQELKQWYKGFLKDCPSGILNLEE--FQQLYIKFF 56
           +N+   A +VL D++QN+   EQE+++     L++      NL+E  F  L+   F
Sbjct: 428 QNDLPKAVDVLSDIIQNSLLGEQEIERERGVILREMQEVETNLQEVVFDHLHATAF 595
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|9055356|ref|NP_061238.1| syntaxin 8 [Mus musculus]
         (236 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

07259                                                                  59   1e-09
31005                                                                  28   4.3  
39186                                                                  28   4.4  
00131                                                                  27   4.9  
03202                                                                  27   9.7  
>07259
          Length = 993

 Score = 59.3 bits (142), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 25/53 (47%), Positives = 39/53 (73%)
 Frame = +2

Query: 166 KQMGQEIGNELDEQNEIIDDLANLVENTDEKLRTEARRVTLVDRKSTSCGMIM 218
           KQM  +IGNE+D Q+E+IDD+ + V++T  ++R E R + +VDRKS +CG  +
Sbjct: 74  KQMAIDIGNEVDLQDELIDDITDHVDSTGNRIRRETRHIAIVDRKSNTCGYYI 232
>31005
          Length = 1261

 Score = 27.7 bits (60), Expect = 4.3,   Method: Compositional matrix adjust.
 Identities = 12/26 (46%), Positives = 18/26 (69%)
 Frame = +3

Query: 166  KQMGQEIGNELDEQNEIIDDLANLVE 191
            KQ  +E GNE++E+NEI   + N V+
Sbjct: 1002 KQKSEEAGNEINERNEIYRSIYNYVK 1079
>39186
          Length = 728

 Score = 27.7 bits (60), Expect = 4.4,   Method: Compositional matrix adjust.
 Identities = 9/20 (45%), Positives = 14/20 (70%)
 Frame = -3

Query: 156 DALSSIISRQKQMGQEIGNE 175
           D  + ++ RQKQ+G  +GNE
Sbjct: 552 DGWTGVLDRQKQLGHRLGNE 493
>00131
          Length = 1971

 Score = 27.3 bits (59), Expect = 4.9,   Method: Compositional matrix adjust.
 Identities = 9/20 (45%), Positives = 14/20 (70%)
 Frame = +3

Query: 156 DALSSIISRQKQMGQEIGNE 175
           D  + ++ RQKQ+G  +GNE
Sbjct: 768 DGWTGVLDRQKQLGHRLGNE 827
>03202
          Length = 797

 Score = 26.6 bits (57), Expect = 9.7,   Method: Compositional matrix adjust.
 Identities = 9/15 (60%), Positives = 14/15 (93%)
 Frame = +3

Query: 28  NQCERRGEKTPKLTL 42
           N+C+RR +KTPK++L
Sbjct: 252 NRCDRRSDKTPKISL 296
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|28893085|ref|NP_796102.1| IQ calmodulin-binding motif
containing 1 [Mus musculus]
         (598 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

29771                                                                  60   2e-09
30506                                                                  38   0.011
26093                                                                  37   0.017
20840                                                                  32   0.51 
07247                                                                  30   2.0  
33582                                                                  30   2.5  
16531                                                                  29   4.2  
22689                                                                  29   4.4  
11227                                                                  28   9.5  
>29771
          Length = 404

 Score = 60.5 bits (145), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 44/118 (37%), Positives = 66/118 (55%), Gaps = 3/118 (2%)
 Frame = +2

Query: 230 ATKLLLVLAESHQEILILLRLSACYKGLRSLLNKQETLTEFSRELRQLVDLLTPKIHQEV 289
           A + +L   ESH+ ++ +L   + YKGLR LL + E    F R+L+QL  LL        
Sbjct: 2   AVRTVLRFCESHKPLVEML--YSRYKGLRPLLRRWEG-RGFERDLKQLYTLLQSGSALRA 172

Query: 290 EEQKLHKAACLIQAYWKGFQTRKRLKKLPSAVIALQRSFRSKRTK---MMLELNRQKE 344
           + Q+ ++AA  IQA WKG  TR+RL+K   A    QRS+R ++ +   ++LE   Q E
Sbjct: 173 QSQRKNEAASYIQAIWKGVLTRQRLQKANKAFSKFQRSYRLRKEREDHLLLETQVQTE 346
>30506
          Length = 1317

 Score = 38.1 bits (87), Expect = 0.011,   Method: Compositional matrix adjust.
 Identities = 37/136 (27%), Positives = 57/136 (41%)
 Frame = -1

Query: 288  EVEEQKLHKAACLIQAYWKGFQTRKRLKKLPSAVIALQRSFRSKRTKMMLELNRQKEEED 347
            ++E+ ++ KAA  IQA +KGF++R+  K+   +         + +T+     + Q+EE D
Sbjct: 1185 DLEDPEVEKAAIKIQASFKGFKSRQAQKQAEESTAGASSQSLTGKTE-----DTQEEEVD 1021

Query: 348  LRLKWQLQRQRAMRLSRESRLNMLEIIHPGQVEKYNREMEEKSALTIQKHWRGYRERKNF 407
            + L                         P           EK+AL IQ  +RGYR RK  
Sbjct: 1020 IDLD-----------------------DP---------ETEKAALKIQAGFRGYRTRKEM 937

Query: 408  RQQRPSLTEYKAAVTL 423
              Q P   E KA+  L
Sbjct: 936  S-QAPPADEEKASSPL 892

 Score = 33.5 bits (75), Expect = 0.22,   Method: Compositional matrix adjust.
 Identities = 20/79 (25%), Positives = 43/79 (54%), Gaps = 5/79 (6%)
 Frame = -1

Query: 247  LLRLSACYKGLRSLLNKQE----TLTEFSRELR-QLVDLLTPKIHQEVEEQKLHKAACLI 301
             +++ A +KG +S   +++    T    S+ L  +  D    ++  ++++ +  KAA  I
Sbjct: 1155 AIKIQASFKGFKSRQAQKQAEESTAGASSQSLTGKTEDTQEEEVDIDLDDPETEKAALKI 976

Query: 302  QAYWKGFQTRKRLKKLPSA 320
            QA ++G++TRK + + P A
Sbjct: 975  QAGFRGYRTRKEMSQAPPA 919
>26093
          Length = 1075

 Score = 37.4 bits (85), Expect = 0.017,   Method: Compositional matrix adjust.
 Identities = 39/137 (28%), Positives = 57/137 (41%), Gaps = 1/137 (0%)
 Frame = -1

Query: 288 EVEEQKLHKAACLIQAYWKGFQTRKRLKKL-PSAVIALQRSFRSKRTKMMLELNRQKEEE 346
           ++E+ ++ KAA  IQA +KGF++R+  K+   S   A  +S   K        + Q+EE 
Sbjct: 916 DLEDPEVEKAAIKIQASFKGFKSRQAQKQAEESTAGASSQSLTGKX------EDTQEEEV 755

Query: 347 DLRLKWQLQRQRAMRLSRESRLNMLEIIHPGQVEKYNREMEEKSALTIQKHWRGYRERKN 406
           D+ L                                +    EK+AL IQ  +RGYR RK 
Sbjct: 754 DIDL--------------------------------DDPETEKAALKIQAGFRGYRTRKE 671

Query: 407 FRQQRPSLTEYKAAVTL 423
              Q P   E KA+  L
Sbjct: 670 MS-QAPPADEEKASSPL 623

 Score = 36.6 bits (83), Expect = 0.026,   Method: Compositional matrix adjust.
 Identities = 27/93 (29%), Positives = 40/93 (43%), Gaps = 23/93 (24%)
 Frame = -1

Query: 246 ILLRLSACYKGLRSL----LNKQ---------------ETLTEFSRE----LRQLVDLLT 282
             +++ A +KGL++      NK                ET TE   E     +  +DL  
Sbjct: 520 AAIKIQAGFKGLKARKEINANKTDGEAGAPKEGENTEPETSTEVKEEGQGQAQDDIDLTD 341

Query: 283 PKIHQEVEEQKLHKAACLIQAYWKGFQTRKRLK 315
           P++ Q         AA  IQA +KGF+TR+ LK
Sbjct: 340 PEVQQ---------AAVKIQAGYKGFKTRRDLK 269

 Score = 33.5 bits (75), Expect = 0.24,   Method: Compositional matrix adjust.
 Identities = 25/89 (28%), Positives = 42/89 (47%), Gaps = 14/89 (15%)
 Frame = -1

Query: 246 ILLRLSACYKGLRS-LLNKQ----------ETLT---EFSRELRQLVDLLTPKIHQEVEE 291
             +++ A +KG +S    KQ          ++LT   E ++E    +DL  P+       
Sbjct: 889 AAIKIQASFKGFKSRQAQKQAEESTAGASSQSLTGKXEDTQEEEVDIDLDDPETE----- 725

Query: 292 QKLHKAACLIQAYWKGFQTRKRLKKLPSA 320
               KAA  IQA ++G++TRK + + P A
Sbjct: 724 ----KAALKIQAGFRGYRTRKEMSQAPPA 650
>20840
          Length = 861

 Score = 32.3 bits (72), Expect = 0.51,   Method: Compositional matrix adjust.
 Identities = 15/41 (36%), Positives = 26/41 (63%)
 Frame = +1

Query: 290 EEQKLHKAACLIQAYWKGFQTRKRLKKLPSAVIALQRSFRS 330
           ++QK  +AA LIQ+Y++ ++     KK+  A + +Q  FRS
Sbjct: 7   QQQKEIEAAVLIQSYYRRYKQYAYYKKMTHAAVLIQNQFRS 129
>07247
          Length = 1753

 Score = 30.4 bits (67), Expect = 2.0,   Method: Compositional matrix adjust.
 Identities = 17/48 (35%), Positives = 26/48 (54%), Gaps = 2/48 (4%)
 Frame = -1

Query: 261  LNKQETLTEFSRELRQLVDL--LTPKIHQEVEEQKLHKAACLIQAYWK 306
             N+   L E  RELR++++L  L P++ Q V   +L  A C    YW+
Sbjct: 1537 FNQIGGLGEQVRELREVIELPLLNPELFQRVGITRLKAACCSDPRYWQ 1394
>33582
          Length = 1000

 Score = 30.0 bits (66), Expect = 2.5,   Method: Compositional matrix adjust.
 Identities = 19/60 (31%), Positives = 33/60 (55%)
 Frame = +3

Query: 368 LNMLEIIHPGQVEKYNREMEEKSALTIQKHWRGYRERKNFRQQRPSLTEYKAAVTLQRAV 427
           +N+ EI HP +     +E+   +A+ IQ+H RG+  R+ F + R  +  Y +  T Q+ V
Sbjct: 192 VNIYEIYHPKKTGPTKKELHV-AAIAIQRHIRGWLIRRRFYKLRRKVAWYGS--TFQKMV 362
>16531
          Length = 514

 Score = 29.3 bits (64), Expect = 4.2,   Method: Composition-based stats.
 Identities = 15/39 (38%), Positives = 20/39 (51%)
 Frame = +3

Query: 299 CLIQAYWKGFQTRKRLKKLPSAVIALQRSFRSKRTKMML 337
           CL    W  F  RK  K+ PS+V  L     SKR++ +L
Sbjct: 225 CLKARSWSNFLQRKNRKRNPSSVRPLNSGTFSKRSRNVL 341
>22689
          Length = 1410

 Score = 29.3 bits (64), Expect = 4.4,   Method: Compositional matrix adjust.
 Identities = 13/31 (41%), Positives = 21/31 (67%)
 Frame = +2

Query: 388 EKSALTIQKHWRGYRERKNFRQQRPSLTEYK 418
           +K+A TIQ +++GYR R   + +R +L E K
Sbjct: 938 DKAATTIQSYYKGYRVRTEHKSERQTLAERK 1030
>11227
          Length = 945

 Score = 28.1 bits (61), Expect = 9.5,   Method: Compositional matrix adjust.
 Identities = 13/22 (59%), Positives = 13/22 (59%)
 Frame = -1

Query: 286 HQEVEEQKLHKAACLIQAYWKG 307
           H     QKLHK  CL Q YWKG
Sbjct: 726 HIGFTVQKLHKV-CLFQVYWKG 664
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|30725845|ref|NP_849534.1| AAA-ATPase TOB3 [Mus
musculus]
         (591 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

03022                                                                  60   2e-09
07243                                                                  60   2e-09
01642                                                                  59   6e-09
00810                                                                  54   2e-07
23766                                                                  54   2e-07
20270                                                                  52   9e-07
19129                                                                  51   1e-06
07247                                                                  46   5e-05
12235                                                                  41   0.001
26408                                                                  39   0.006
02582                                                                  35   0.069
17843                                                                  34   0.13 
19561                                                                  34   0.15 
02194                                                                  32   0.59 
01279                                                                  32   0.65 
>03022
          Length = 2255

 Score = 60.5 bits (145), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 64/243 (26%), Positives = 106/243 (43%), Gaps = 7/243 (2%)
 Frame = +2

Query: 319  LSPSLEARVRDIAIATRNTKKNKSLYRNVLMYGPPGTGKTLFAKKLALHSGMDYAIMKGG 378
            L  S+  R+ D  +++       S    +++ GPPG GKTL AK +A  +G+++  +KG 
Sbjct: 1463 LKDSILCRIHDPEVSSAFGLPTNS---GIILVGPPGCGKTLVAKAMANEAGLNFIYIKGP 1633

Query: 379  DVAP--MGREGVTAMHKVFDWASTSRRGLLLFVDEADAFLRKRATEKISEDLRATLN--- 433
            ++    +G E    + + FD A       L+F DE D     R     S   ++  N   
Sbjct: 1634 ELLDKYVG-ESERNLREKFDKAQACAP-CLIFFDEMDTLCSNRQNNDGSNVGKSVTNQLL 1807

Query: 434  AFLHRTGQHSSKFMLVLASNQPEQFDWAIN--DRIDEMVCFALPQREERERLVRMYFDKY 491
            A +   G+ S  +++  A+N  E  D A+    R D  +   LP  + R        D  
Sbjct: 1808 ALMDGCGERSQVYVMG-ATNIIENVDPALQRPGRFDRKIFIGLPDTDGR-------LD-- 1957

Query: 492  VLKPATEGKQRLKVAQFDYGKKCSEVAQLTEGMSGREIAQLAVAWQAMAYSSEDGVLTEA 551
            +L+  T+G  + K+   D      ++AQ TEG SG ++  L      +A       L E+
Sbjct: 1958 ILRALTKGGSQRKLESCDM----QQLAQDTEGFSGADLKHLVNEASTIA-------LKES 2104

Query: 552  MMD 554
            M D
Sbjct: 2105 MAD 2113
>07243
          Length = 1112

 Score = 60.1 bits (144), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 43/152 (28%), Positives = 82/152 (53%), Gaps = 9/152 (5%)
 Frame = +1

Query: 345 RNVLMYGPPGTGKTLFAKKLALHSGMDYAIMKGGDVAPMGR---EGVTAMHKVFDWASTS 401
           +  L+YGPPGTGKTL A+ +A  S +D   +K    A + +   E    + ++F++A   
Sbjct: 310 KGCLLYGPPGTGKTLLARAVA--SQLDANFLKVVSSAIVDKYIGESARLIREMFNYAR-D 480

Query: 402 RRGLLLFVDEADAFLRKRATEKISED--LRATLNAFLHRTGQHSS--KFMLVLASNQPEQ 457
            +  ++F+DE DA   +R +E  S D  ++ TL   L++     S  +  +++A+N+P+ 
Sbjct: 481 HQPCIIFMDEIDAIGGRRFSEGTSADREIQRTLMELLNQMDGFDSLGQVKMIMATNRPDT 660

Query: 458 FDWAI--NDRIDEMVCFALPQREERERLVRMY 487
            D A+    R+D  +   LP  + R  +++++
Sbjct: 661 LDPALLRPGRLDRKIEIPLPNEQARLEILKIH 756
>01642
          Length = 1406

 Score = 58.9 bits (141), Expect = 6e-09,   Method: Compositional matrix adjust.
 Identities = 46/148 (31%), Positives = 71/148 (47%), Gaps = 8/148 (5%)
 Frame = -1

Query: 345 RNVLMYGPPGTGKTLFAKKLALHSGMDYAIMKGGD-VAPMGREGVTAMHKVFDWASTSRR 403
           R VLMYGPPG GKT+ AK +A H+   +  + G + V     EG   +  VF  A  +  
Sbjct: 890 RGVLMYGPPGCGKTMLAKAVAHHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAP 711

Query: 404 GLLLFVDEADAFLRKRATEKISEDLRATLNAFLHRTGQ-----HSSKFMLVLASNQPEQF 458
             ++F+DE DA   KR   +   D R      L    Q      +    +++A+N+ +  
Sbjct: 710 A-IIFIDEIDAIATKRFDAQTGAD-REVQRILLELLNQMDGFDQTVNVKVIMATNRADTL 537

Query: 459 DWAI--NDRIDEMVCFALPQREERERLV 484
           D A+    R+D  + F LP R ++ RL+
Sbjct: 536 DPALLRPGRLDRKIEFPLPDRRQK-RLI 456
>00810
          Length = 1431

 Score = 53.9 bits (128), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 52/198 (26%), Positives = 88/198 (44%), Gaps = 7/198 (3%)
 Frame = -3

Query: 345  RNVLMYGPPGTGKTLFAKKLALHSGMDYAIMKGGD-VAPMGREGVTAMHKVFDWASTSRR 403
            + VL++GPPG GKT+ AK  A  +G  +  ++    V     E       VF  A    +
Sbjct: 1336 KGVLLHGPPGCGKTMIAKATAKAAGARFINLQVSSLVDKWYGESQKRAEAVFSLA-IKLQ 1160

Query: 404  GLLLFVDEADAFLRKR------ATEKISEDLRATLNAFLHRTGQHSSKFMLVLASNQPEQ 457
              ++F+DE D+FLR R      AT  I     +  +  +        + M++ A+N+P+ 
Sbjct: 1159 PTIIFIDEIDSFLRSRTSTDHEATAMIKTQFMSFWDGLM---TDPDCRVMVMGATNRPQD 989

Query: 458  FDWAINDRIDEMVCFALPQREERERLVRMYFDKYVLKPATEGKQRLKVAQFDYGKKCSEV 517
             D AI  R+  M    LP   +R  +  +             K+R+    +D      E+
Sbjct: 988  VDAAILRRMPSMFHIGLPGPAQRRSIFNLIL----------SKERIDALNYD------EL 857

Query: 518  AQLTEGMSGREIAQLAVA 535
            A++T+G SG +I ++  A
Sbjct: 856  AEMTDGFSGSDIREVCRA 803
>23766
          Length = 1463

 Score = 53.5 bits (127), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 44/163 (26%), Positives = 80/163 (49%), Gaps = 14/163 (8%)
 Frame = +1

Query: 345 RNVLMYGPPGTGKTLFAKKLALHSGMDYAIMKG--------GDVAPMGREGVTAMHKVFD 396
           + V++YGPPGTGKTL AK +A  +   +  + G        GD   + RE    + +V +
Sbjct: 157 KGVILYGPPGTGKTLLAKAVANQTSATFLRVVGSELIQKYLGDGPKLVRE----LFRVAE 324

Query: 397 WASTSRRGLLLFVDEADAFLRKR--ATEKISEDLRATLNAFLHRTGQHSSK--FMLVLAS 452
             + S    ++F+DE DA   KR  +      +++ T+   L++     S+    +++A+
Sbjct: 325 EHAPS----IVFIDEIDAVGTKRYESNSGGEREIQRTMLELLNQLDGFDSRGDVKVIMAT 492

Query: 453 NQPEQFDWAI--NDRIDEMVCFALPQREERERLVRMYFDKYVL 493
           N+ E  D A+    RID  + F LP  + + R+  ++  +  L
Sbjct: 493 NRIETLDPALIRPGRIDRKIEFPLPDEKTKRRIFTIHTSRMTL 621
>20270
          Length = 542

 Score = 51.6 bits (122), Expect = 9e-07,   Method: Compositional matrix adjust.
 Identities = 37/129 (28%), Positives = 62/129 (48%), Gaps = 5/129 (3%)
 Frame = -3

Query: 344 YRNVLMYGPPGTGKTLFAKKLALHSGMD--YAIMKGGDVAPMGREGVTAMHKVFDWASTS 401
           +R +L+YGPPGTGK+  AK +A  +     +++     V+    E    +  +F  A  +
Sbjct: 381 WRGILLYGPPGTGKSYLAKAVATEANNSTFFSVSSSDLVSKWLGESEKLVKTLFQLAREN 202

Query: 402 RRGLLLFVDEADAFLRKRATEKISEDLRATLNAFL---HRTGQHSSKFMLVLASNQPEQF 458
           +   ++F+DE DA    R +E  SE  R     FL      G  ++  +++ A+N P   
Sbjct: 201 QPS-IIFIDEVDALCGSR-SENESESARRIKTEFLVQMQGVGNDNTGVLVLGATNIPWTL 28

Query: 459 DWAINDRID 467
           D AI  R +
Sbjct: 27  DSAIRRRFE 1
>19129
          Length = 1020

 Score = 51.2 bits (121), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 42/143 (29%), Positives = 67/143 (46%), Gaps = 7/143 (4%)
 Frame = +1

Query: 345 RNVLMYGPPGTGKTLFAKKLALHSGMDYAIMKGGD-VAPMGREGVTAMHKVFDWASTSRR 403
           + VL+YGPPGTGKTL A+ +A H+   +  + G + V     EG   + ++F  A     
Sbjct: 592 KGVLLYGPPGTGKTLLARAVAHHTECTFIRVSGSELVQKFIGEGSRMVRELFVMAREHAP 771

Query: 404 GLLLFVDEADAFLRKR---ATEKISEDLRATLNAFLHRTG-QHSSKFMLVLASNQPEQFD 459
             ++F+DE D+    R    +   SE  R  L       G +      +++A+N+ +  D
Sbjct: 772 S-IIFMDEIDSIGSSRLEGGSGGDSEVQRTMLELLNQLDGFEPKQNIKVIMATNRIDILD 948

Query: 460 WAI--NDRIDEMVCFALPQREER 480
            A+    RID  + F  P  E R
Sbjct: 949 SALLRPGRIDRKIEFPPPNEEAR 1017
>07247
          Length = 1753

 Score = 45.8 bits (107), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 51/213 (23%), Positives = 99/213 (46%), Gaps = 10/213 (4%)
 Frame = -2

Query: 353  PGTGKTLFAKKLALHSGMDYAIMKGGDVAPMGR---EGVTAMHKVFDWASTSRRGLLLFV 409
            PGTGKTL A+ +A  S +D   +K    A + +   E    + ++F +A       ++F+
Sbjct: 1407 PGTGKTLLARAVA--SQLDCNFLKVVSSAIVDKYIGESARLIREMFAFAR-DHEPCIIFM 1237

Query: 410  DEADAFLRKRATEKISED--LRATLNAFLHRTGQHSS--KFMLVLASNQPEQFDWAI--N 463
            DE DA   +R +E  S D  ++ TL   L++     +  +  +++A+N+P+  D A+   
Sbjct: 1236 DEIDAIGGRRFSEGTSADREIQRTLMELLNQMDGFDALGQVKMIMATNRPDTLDPALLRP 1057

Query: 464  DRIDEMVCFALPQREERERLVRMYFDKYVLKPATEGKQRLKVAQFDYGKKCSEVAQLTEG 523
             R+D  +  +LP  + R  +++++ +              K  + D+      V +L+E 
Sbjct: 1056 GRLDRKIEISLPNEQARLEILKIHANPIA-----------KHGEIDW----EAVVKLSED 922

Query: 524  MSGREIAQLAVAWQAMAYSSE-DGVLTEAMMDA 555
             +G ++  +       A  +E D V+ E  M A
Sbjct: 921  FNGADLRNVCTEAGMFAIRAERDYVIEEDFMKA 823
>12235
          Length = 1749

 Score = 41.2 bits (95), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 42/149 (28%), Positives = 70/149 (46%), Gaps = 8/149 (5%)
 Frame = +1

Query: 393 KVFDWASTSRRG--LLLFVDEADAFLRKRATEKIS--EDLRATLNAFL-HRTGQHSSKFM 447
           +V D  +T+R+    +LFVDE DA  RKR+        +   TLN  L    G ++   +
Sbjct: 73  RVRDMFATARKNAPCILFVDEIDAVGRKRSGRNFGGQSEQENTLNQLLVEMDGFNTQTGV 252

Query: 448 LVL-ASNQPEQFDWAI--NDRIDEMVCFALPQREERERLVRMYFDKYVLKPATEGKQRLK 504
           +VL A+N+ +  D A+    R D  +   LP  + R  + +++ D            + +
Sbjct: 253 VVLAATNRVDILDAALLRPGRFDRQIFVPLPDIKXRASIFKVHLDPL----------KTE 402

Query: 505 VAQFDYGKKCSEVAQLTEGMSGREIAQLA 533
           V + D  +K   +A LT G SG +IA + 
Sbjct: 403 VNKNDLARK---MAALTPGFSGADIANVC 480
>26408
          Length = 463

 Score = 38.9 bits (89), Expect = 0.006,   Method: Composition-based stats.
 Identities = 15/24 (62%), Positives = 20/24 (83%)
 Frame = +1

Query: 345 RNVLMYGPPGTGKTLFAKKLALHS 368
           + VL+YGPPGTGKTL A+ +A H+
Sbjct: 367 KGVLLYGPPGTGKTLLARAVAHHT 438
>02582
          Length = 1101

 Score = 35.4 bits (80), Expect = 0.069,   Method: Compositional matrix adjust.
 Identities = 53/232 (22%), Positives = 90/232 (38%), Gaps = 41/232 (17%)
 Frame = +3

Query: 343 LYRNVLMYGPPGTGKTLFAKKLALHSGMDYAIMKGGDV-APMGREGVTAMHKVFDWASTS 401
           L + VL+YGPPG GKT  A+  A    + +  +    + +P   +    + + F  A   
Sbjct: 240 LTKGVLLYGPPGCGKTTLAQAAATACHVTFLSLSCAQLYSPYVGDAEKKISETFQKA--- 410

Query: 402 RRGL---LLFVDEADAFLRKRATEKISEDLRA-TLNAFLHRTG----------------- 440
            R L   +LF+DE DA + KR+   +   +    L+A L+                    
Sbjct: 411 -RALAPSILFLDEMDAIVGKRSDSSLGSGVSERVLSALLNEMDGIGVRLDDKSDSREMEI 587

Query: 441 -----------QHSSK------FMLVLASNQPEQFDWAI--NDRIDEMVCFALPQREERE 481
                      QH+ K       ++V A+N+P+  D A+    R+D ++    P  + R 
Sbjct: 588 EGSSDHTPQVRQHAVKEAHDRHVLVVAATNRPDMLDPALLRPGRMDRLIYVPPPDVQGRL 767

Query: 482 RLVRMYFDKYVLKPATEGKQRLKVAQFDYGKKCSEVAQLTEGMSGREIAQLA 533
           +   ++  K  L    + KQ               +A LT G +G +I  L 
Sbjct: 768 QSFTIHTRKMPLGKDVDVKQ---------------LADLTAGYTGADIKTLC 878
>17843
          Length = 772

 Score = 34.3 bits (77), Expect = 0.13,   Method: Compositional matrix adjust.
 Identities = 13/21 (61%), Positives = 16/21 (76%)
 Frame = +1

Query: 345 RNVLMYGPPGTGKTLFAKKLA 365
           R +L++GPPGTGKT   K LA
Sbjct: 187 RVILLHGPPGTGKTTLCKALA 249
>19561
          Length = 474

 Score = 34.3 bits (77), Expect = 0.15,   Method: Compositional matrix adjust.
 Identities = 24/72 (33%), Positives = 29/72 (40%), Gaps = 5/72 (6%)
 Frame = -1

Query: 348 LMYGPPGTGKTLFAKKLALHSGMDYAIMKGGD-----VAPMGREGVTAMHKVFDWASTSR 402
           L+ GPPG GKT  A  +A H+G +   M   D     V     E  T M  V        
Sbjct: 369 LLCGPPGLGKTTLAHIVAKHAGYNVVEMNASDDRSVEVFSNKIEAATQMRAVM---GADP 199

Query: 403 RGLLLFVDEADA 414
           R   L +DE D 
Sbjct: 198 RPNCLIIDEIDG 163
>02194
          Length = 1891

 Score = 32.3 bits (72), Expect = 0.59,   Method: Compositional matrix adjust.
 Identities = 14/30 (46%), Positives = 19/30 (63%)
 Frame = -1

Query: 345  RNVLMYGPPGTGKTLFAKKLALHSGMDYAI 374
            R  L+YGPPG GK+ +   +AL   +DY I
Sbjct: 1495 RGYLLYGPPGCGKSSYI--MALAGALDYNI 1412
>01279
          Length = 2183

 Score = 32.0 bits (71), Expect = 0.65,   Method: Compositional matrix adjust.
 Identities = 19/45 (42%), Positives = 25/45 (55%), Gaps = 2/45 (4%)
 Frame = -3

Query: 338  KKNKSLYRNVLMYGPPGTGKTLFAKKLA--LHSGMDYAIMKGGDV 380
            K  K   R VL+ GPPGTGKT  A  +A  L + + +  M G +V
Sbjct: 1935 KTKKMAGRAVLLAGPPGTGKTAIALAIAQELGNKVPFCPMVGSEV 1801
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31543274|ref|NP_058084.2| metaxin 2 [Mus musculus]
         (263 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

27365                                                                  59   2e-09
36287                                                                  31   0.64 
>27365
          Length = 860

 Score = 58.9 bits (141), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 47/217 (21%), Positives = 99/217 (45%), Gaps = 1/217 (0%)
 Frame = +1

Query: 42  LAVQAFLQMCNLPVKVVCRANAEYMSPSGKVPFIHVGNQVVSELGPIVQFVKAKGHY-LS 100
           + ++ +L+M  +P +     +    S  GK+P++    + V++    + ++  + +  LS
Sbjct: 127 VKLETYLRMAKIPYQ---NDHGMKQSSKGKIPWMTYNGEDVADSSFCIHYLNTRLNVDLS 297

Query: 101 DGLDEVQKAEMKAYMKLVNNMLLTAELYLQWCDEATVGEITIARYGSPYPWPLNHILAYQ 160
             L   Q+A   A  +LV + L    +  +W  E     +  A  G    +P+  +  + 
Sbjct: 298 AFLTPEQRAVEVALQRLVEDDLYWVMVVTRWLKEVDEDFVRKA-LGLSMSFPILMLKLFF 474

Query: 161 KQWEVKRKMKAIGWGNKTLDQVLEDVDQCCQALSQRLGTQPYFFNKQPTELDALVFGHLY 220
           K   +++   A G G  ++D +     +   ALS  LGT+ +    +P E+D  +FG L 
Sbjct: 475 KP-AIRKMTHAQGMGRHSMDDIRHIARKDLTALSDYLGTKKFIMGDRPCEVDCAIFGQLS 651

Query: 221 TILTTQLTSDELSEKVKNYSNLLAFCRRIEQHYFEDW 257
            +   Q+ S       + Y  L+++C R+++ ++ DW
Sbjct: 652 QVY-WQMPSSISRXFKEEYPRLVSYCERMKETFWPDW 759
>36287
          Length = 455

 Score = 30.8 bits (68), Expect = 0.64,   Method: Compositional matrix adjust.
 Identities = 16/45 (35%), Positives = 23/45 (51%)
 Frame = +2

Query: 56  KVVCRANAEYMSPSGKVPFIHVGNQVVSELGPIVQFVKAKGHYLS 100
           +V CR +AE  SP G    +    + +   GPI Q  +A+G  LS
Sbjct: 17  RVECRVDAEGKSPEGVGQAVKSDWEEIETRGPIPQKQRARGSELS 151
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|19527322|ref|NP_598854.1| LETM1 domain containing 1
[Mus musculus]
         (360 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

27118                                                                  59   3e-09
30661                                                                  29   3.5  
15019                                                                  28   5.1  
21624                                                                  28   8.2  
>27118
          Length = 420

 Score = 58.9 bits (141), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 37/135 (27%), Positives = 68/135 (50%)
 Frame = -3

Query: 102 KARRIKADMWKQNLKFHQLSYREMEHLRQFRRDITKCLFVGLISIPPFANYLVFLLMYLF 161
           K  RI A++  Q ++   L+ +E+E   Q  RD+ K     +    P   Y  F L++++
Sbjct: 397 KVARI-ANVLPQGIR--ALNRQELELYMQMPRDMMKVAPALIGCSLPMVGYAFFPLVFMY 227

Query: 162 PRQLLVKHFWTPKQQIDFLDVYHGLRRRSHSEVITHLRRASTFVSHEKLRRQLTDLCTKV 221
           PR  L  HFWTP+Q+++F   Y   R + +  V+  L+     V+      +   +  ++
Sbjct: 226 PRTFLTPHFWTPEQRVEFQTFYIKRRLQCNKPVLRCLQAKLKSVALHPHHAEFECILGQL 47

Query: 222 QSGTHPAAQDVLALR 236
            SGTHP  + ++A++
Sbjct: 46  GSGTHPTPEALIAIK 2
>30661
          Length = 380

 Score = 28.9 bits (63), Expect = 3.5,   Method: Compositional matrix adjust.
 Identities = 11/22 (50%), Positives = 17/22 (77%)
 Frame = -2

Query: 37  WRAPRSSKLHLSPKADVKNLIS 58
           W APR++ +H SP+A  +NL+S
Sbjct: 187 WVAPRNTMVHASPRATPENLMS 122
>15019
          Length = 1073

 Score = 28.1 bits (61), Expect = 5.1,   Method: Compositional matrix adjust.
 Identities = 10/24 (41%), Positives = 16/24 (66%)
 Frame = -3

Query: 100 GKKARRIKADMWKQNLKFHQLSYR 123
           GK+A ++   + KQN+ F Q +YR
Sbjct: 975 GKQANKVIITVLKQNVTFSQFAYR 904
>21624
          Length = 447

 Score = 27.7 bits (60), Expect = 8.2,   Method: Compositional matrix adjust.
 Identities = 10/17 (58%), Positives = 13/17 (76%)
 Frame = +3

Query: 305 SACYLRGLNSTHIADDR 321
           S+CYLRGLNS H++   
Sbjct: 231 SSCYLRGLNSVHLSGSN 281
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|39930599|ref|NP_766470.2| WD repeat and FYVE domain
containing 3 [Mus musculus]
         (3508 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

29146                                                                  62   3e-09
33803                                                                  57   2e-07
05474                                                                  54   2e-06
27465                                                                  52   5e-06
30256                                                                  52   6e-06
28053                                                                  48   6e-05
27911                                                                  45   4e-04
12806                                                                  42   0.005
18981                                                                  42   0.006
13335                                                                  41   0.011
03387                                                                  39   0.032
10264                                                                  39   0.040
00561                                                                  38   0.065
01598                                                                  38   0.080
17598                                                                  38   0.084
37180                                                                  36   0.24 
30295                                                                  36   0.25 
16199                                                                  35   0.52 
03734                                                                  34   0.85 
19949                                                                  34   1.2  
06775                                                                  33   2.3  
15780                                                                  33   2.5  
12574                                                                  33   2.6  
22415                                                                  32   3.6  
17266                                                                  32   3.7  
26107                                                                  32   4.8  
01249                                                                  32   5.5  
19140                                                                  31   8.3  
>29146
          Length = 327

 Score = 62.4 bits (150), Expect = 3e-09,   Method: Composition-based stats.
 Identities = 25/61 (40%), Positives = 32/61 (52%), Gaps = 2/61 (3%)
 Frame = +3

Query: 3433 WVKDEGGDSCSG--CSVRFSLTERRHHCRNCGQLFCQKCSRFQSEIKRLKISSPVRVCQN 3490
            W  D     C    C  +F L  R+HHCR CG+ FC KC+  Q+ + R+    PVR C N
Sbjct: 90   WTPDGSCKVCQNVQCQAKFDLFNRKHHCRRCGKCFCNKCTTGQAVLPRMCFVDPVRHCDN 269

Query: 3491 C 3491
            C
Sbjct: 270  C 272
>33803
          Length = 510

 Score = 56.6 bits (135), Expect = 2e-07,   Method: Composition-based stats.
 Identities = 24/61 (39%), Positives = 31/61 (50%)
 Frame = +2

Query: 3431 DHWVKDEGGDSCSGCSVRFSLTERRHHCRNCGQLFCQKCSRFQSEIKRLKISSPVRVCQN 3490
            ++WV DE  + C  C + F+     HHCR CGQ  C  CS  + E+       PVRVC  
Sbjct: 251  EYWVPDEAINECIVCQLEFNPKRPIHHCRACGQGVCHDCSPNRREVPLRGWDYPVRVCSK 430

Query: 3491 C 3491
            C
Sbjct: 431  C 433
>05474
          Length = 1214

 Score = 53.5 bits (127), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 27/74 (36%), Positives = 38/74 (51%), Gaps = 1/74 (1%)
 Frame = +1

Query: 3433 WVKDEGGDSCSGCS-VRFSLTERRHHCRNCGQLFCQKCSRFQSEIKRLKISSPVRVCQNC 3491
            WV D    +C  C    F+L  RRHHCR+CG + C  CS  +  + + + S P+RVC  C
Sbjct: 349  WVPDSDTKTCMHCKKSEFTLINRRHHCRHCGIVACNACSSKRWLLPQ-QSSRPLRVCLTC 525

Query: 3492 YYSLQHERGAEDGP 3505
            Y+ L  +      P
Sbjct: 526  YHRLSSKNSQNSRP 567
>27465
          Length = 658

 Score = 52.0 bits (123), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 36/112 (32%), Positives = 49/112 (43%), Gaps = 3/112 (2%)
 Frame = -1

Query: 3124 IVSGSRDRTCIIWDLNKLSFLTQLRGHRAPVSALCINELTGDIVSCAGTY---IHVWSIN 3180
             ++GS DRTC IWD      L  L GHR  V A+  N   GD V   G++     +WS  
Sbjct: 316  FITGSYDRTCKIWDTASAEELHTLEGHRNVVYAIAFNNPFGDKV-ITGSFDKTCKLWSTA 140

Query: 3181 GNPIVSVNTFTGRSQQIVCCCMSEMNEWDTQNVIVTGHSDGVVRFWRMEFLQ 3232
                   +T  G + +IVC   +      +  +I TG  D   R W +E  Q
Sbjct: 139  DGK--CYHTLRGHTAEIVCVSFNP-----SSTLIATGSMDTTCRLWDVEKAQ 5
>30256
          Length = 961

 Score = 51.6 bits (122), Expect = 6e-06,   Method: Composition-based stats.
 Identities = 44/153 (28%), Positives = 65/153 (42%), Gaps = 1/153 (0%)
 Frame = +3

Query: 3075 VITGGTSTVVCVWEMGTSKEKAKPLTLKQALLGHTDTVTCATASLAYHIIVSGSRDRTCI 3134
            VI+G T   + VW   T             L GH+ TV C   SL+   +VSGSRD T  
Sbjct: 81   VISGSTDRSLKVWNADTG-------VCTHTLYGHSSTVRCL--SLSGKKVVSGSRDATLR 233

Query: 3135 IWDLNKLSFLTQLRGHRAPVSALCINELTGDIVSCAGTY-IHVWSINGNPIVSVNTFTGR 3193
            +WD+     L  L GH A V   C+      +VS A  Y + VW  + +    ++T  G 
Sbjct: 234  VWDIESGHCLNVLLGHMAAVR--CVQYDGKRVVSGAXDYTVRVW--DPDTASCLHTLQGH 401

Query: 3194 SQQIVCCCMSEMNEWDTQNVIVTGHSDGVVRFW 3226
            + ++       +        +V+G  D  +R W
Sbjct: 402  TNRVYSLQFDGV-------YVVSGSLDTSIRVW 479

 Score = 40.4 bits (93), Expect = 0.012,   Method: Composition-based stats.
 Identities = 32/111 (28%), Positives = 55/111 (49%), Gaps = 5/111 (4%)
 Frame = +3

Query: 3075 VITGGTSTVVCVWEMGTSKEKAKPLTLKQALLGHTDTVTCATASLAYHIIVSGSRDRTCI 3134
            V++G   T + VW++   K       L   L+GH    +     L  +++VSG+ D T  
Sbjct: 441  VVSGSLDTSIRVWDVRCGK-------LVHTLMGHQSLTS--GLELKDNLLVSGNADSTVK 593

Query: 3135 IWDLNKLSFLTQLRG---HRAPVSALCINELTGDIVSCA--GTYIHVWSIN 3180
            +WD++    L  L G   HR+ V+ L  N+    +V+C+  GT + +W +N
Sbjct: 594  VWDVHTGKCLQTLLGPNKHRSAVTCLQFNKKF--VVTCSDDGT-VKLWDLN 737

 Score = 37.0 bits (84), Expect = 0.12,   Method: Composition-based stats.
 Identities = 33/124 (26%), Positives = 53/124 (42%), Gaps = 2/124 (1%)
 Frame = +3

Query: 3105 LLGHTDTVTCATASLAYHIIVSGSRDRTCIIWDLNKLSFLTQLRGHRAPVSALCINELTG 3164
            L+GHT  V   ++ +  + ++SGS DR+  +W+ +       L GH + V  L    L+G
Sbjct: 30   LIGHTGGVW--SSQMTGNTVISGSTDRSLKVWNADTGVCTHTLYGHSSTVRCL---SLSG 194

Query: 3165 DIVSCAG--TYIHVWSINGNPIVSVNTFTGRSQQIVCCCMSEMNEWDTQNVIVTGHSDGV 3222
              V        + VW I       +N   G    + C       ++D + V V+G  D  
Sbjct: 195  KKVVSGSRDATLRVWDIESGH--CLNVLLGHMAAVRCV------QYDGKRV-VSGAXDYT 347

Query: 3223 VRFW 3226
            VR W
Sbjct: 348  VRVW 359
>28053
          Length = 441

 Score = 48.1 bits (113), Expect = 6e-05,   Method: Compositional matrix adjust.
 Identities = 19/41 (46%), Positives = 24/41 (58%)
 Frame = -2

Query: 3432 HWVKDEGGDSCSGCSVRFSLTERRHHCRNCGQLFCQKCSRF 3472
             W+ D+   +C  C   F L  RRHHCR CG + C KCS+F
Sbjct: 341  RWIPDKEVPACLTCIKSFGLLVRRHHCRLCGGIMCNKCSQF 219
>27911
          Length = 376

 Score = 45.4 bits (106), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 20/56 (35%), Positives = 33/56 (58%), Gaps = 5/56 (8%)
 Frame = -2

Query: 3420 SVSDQPGRSAADHWV-----KDEGGDSCSGCSVRFSLTERRHHCRNCGQLFCQKCS 3470
            S +  P RS+   W       ++  + C+ C   FS+T+R+HHCR+CG++FC  C+
Sbjct: 195  SANRSPSRSSELEWAL*SRQHEDDVEDCNNCRQAFSVTKRKHHCRHCGRIFCADCT 28
>12806
          Length = 961

 Score = 41.6 bits (96), Expect = 0.005,   Method: Composition-based stats.
 Identities = 28/98 (28%), Positives = 45/98 (45%), Gaps = 7/98 (7%)
 Frame = +3

Query: 3067 AVCPNPKLVITGGTSTVVCVWE-MGTSKEKAKPLTLKQALLGHTDTVTCATASLAYH--- 3122
            A  P+ + + +GG    + +W  MG  K              HTD VTC    + +H   
Sbjct: 312  AFSPDNRQIASGGRDKNLKIWNIMGECKYTVDAN-------AHTDWVTC----VRFHQDT 458

Query: 3123 ---IIVSGSRDRTCIIWDLNKLSFLTQLRGHRAPVSAL 3157
               I+VS S D+T  +WD + ++      GH+A ++AL
Sbjct: 459  KNPIVVSASNDKTIKVWDNHTMTLKNTFVGHKAQITAL 572

 Score = 40.4 bits (93), Expect = 0.011,   Method: Composition-based stats.
 Identities = 34/158 (21%), Positives = 68/158 (43%), Gaps = 5/158 (3%)
 Frame = +3

Query: 3074 LVITGGTSTVVCVWEMGTSKEKAKPLTL---KQALLGHTDTVTCATASLAYHIIVSGSRD 3130
             +I+GG    + VW++   K+  +  T    ++ L GH+  ++    S      +S S D
Sbjct: 51   FLISGGRDNNIIVWDL*PKKDGDEDQTWGVPRKTLTGHSHFISDLALSADSRFALSSSWD 230

Query: 3131 RTCIIWDLNKLSFLTQLRGHRAPVSALCINELTGDIVSCA-GTYIHVWSINGNPIVSVNT 3189
             T  +WD+ K S  ++   H   V  +  +     I S      + +W+I G    +V+ 
Sbjct: 231  ATLRLWDIKKGSTTSRFINHTRDVLTVAFSPDNRQIASGGRDKNLKIWNIMGECKYTVDA 410

Query: 3190 FTGRSQQIVCCCMSEMNEWDTQN-VIVTGHSDGVVRFW 3226
                +  + C    +    DT+N ++V+  +D  ++ W
Sbjct: 411  -NAHTDWVTCVRFHQ----DTKNPIVVSASNDKTIKVW 509

 Score = 37.0 bits (84), Expect = 0.13,   Method: Composition-based stats.
 Identities = 22/77 (28%), Positives = 39/77 (50%)
 Frame = +3

Query: 3071 NPKLVITGGTSTVVCVWEMGTSKEKAKPLTLKQALLGHTDTVTCATASLAYHIIVSGSRD 3130
            NP +V++      + VW+  T       +TLK   +GH   +T    S  Y  +VSGS+D
Sbjct: 462  NP-IVVSASNDKTIKVWDNHT-------MTLKNTFVGHKAQITALDMSTNY--LVSGSKD 611

Query: 3131 RTCIIWDLNKLSFLTQL 3147
               + W++ + SF+ ++
Sbjct: 612  GIAMTWNVAEGSFVGKI 662
>18981
          Length = 407

 Score = 41.6 bits (96), Expect = 0.006,   Method: Composition-based stats.
 Identities = 33/109 (30%), Positives = 48/109 (44%), Gaps = 1/109 (0%)
 Frame = -2

Query: 3122 HIIVSGSRDRTCIIWDLNKLSFLTQLRGHRAPVSALCINELTGDIVSCAGTYIHVWSIN- 3180
            ++I+S + DRT  +W L     L  LRGH   V  +CI        S   T I VW ++ 
Sbjct: 385  NMIISAATDRTLRVWCLKNTCLLHTLRGHNDDVECVCIYGRRVVSGSWDKTLI-VWEVDT 209

Query: 3181 GNPIVSVNTFTGRSQQIVCCCMSEMNEWDTQNVIVTGHSDGVVRFWRME 3229
            G P   V+   G ++ I      E          V+G +DG VR W ++
Sbjct: 208  GRP---VHQLHGHTEAITAVQFDEGKA-------VSGSADGDVRTWALD 92
>13335
          Length = 863

 Score = 40.8 bits (94), Expect = 0.011,   Method: Compositional matrix adjust.
 Identities = 43/184 (23%), Positives = 78/184 (42%), Gaps = 22/184 (11%)
 Frame = +1

Query: 3065 LCAVCPNPKLVITGGTSTVVCVWEMGTSKEKAKPLTLKQALLGHTDTVTCATASLAYHII 3124
            +C   P+   +++G     +C+WE+ T K       L ++ +GH D+V     S   H +
Sbjct: 76   VCKFSPSSSHLVSGSDDDTICMWEVATQK-------LVRSYVGHEDSVMALAYSPNGHYL 234

Query: 3125 VSGSRDRTCIIWD--LNKLSFLT-QLRGHRAPV----------SALCINELTGDIVSCAG 3171
            VSGS +    +WD        LT ++  H   V          +A   N  T +++   G
Sbjct: 235  VSGSPNGDLYVWDASFGHCRHLTLRVDAHDLGVTCCEFSPTFGTACAENSSTCNLLLATG 414

Query: 3172 ---TYIHVWSIN---GNPIVSV---NTFTGRSQQIVCCCMSEMNEWDTQNVIVTGHSDGV 3222
                 I +W+ +   G+P V++   +  +G S  ++ C  S      +  ++ +G  D  
Sbjct: 415  GKDNLIKLWTFSAQVGSPEVTLQCRDILSGHSDLVMACAFSP-----SSALLASGSFDKS 579

Query: 3223 VRFW 3226
            VR W
Sbjct: 580  VRLW 591

 Score = 33.5 bits (75), Expect = 1.7,   Method: Compositional matrix adjust.
 Identities = 23/79 (29%), Positives = 34/79 (43%)
 Frame = +1

Query: 3064 ILCAVCPNPKLVITGGTSTVVCVWEMGTSKEKAKPLTLKQALLGHTDTVTCATASLAYHI 3123
            + CA  P+  L+ +G     V +W+        K + L      H+  VTC   S+   +
Sbjct: 520  MACAFSPSSALLASGSFDKSVRLWD------SVKGVALFSIEACHSRFVTCCAFSIDGTL 681

Query: 3124 IVSGSRDRTCIIWDLNKLS 3142
            + SGS DR   IW L   S
Sbjct: 682  LASGSMDRIIKIWKLTDTS 738

 Score = 32.3 bits (72), Expect = 3.7,   Method: Compositional matrix adjust.
 Identities = 26/112 (23%), Positives = 47/112 (41%), Gaps = 5/112 (4%)
 Frame = +1

Query: 3074 LVITGGTSTVVCVWEMGTSKEKAKP---LTLKQALLGHTDTVTCATASLAYHIIVSGSRD 3130
            L+ TGG   ++ +W    S +   P   L  +  L GH+D V     S +  ++ SGS D
Sbjct: 400  LLATGGKDNLIKLWTF--SAQVGSPEVTLQCRDILSGHSDLVMACAFSPSSALLASGSFD 573

Query: 3131 RTCIIWDLNKLSFLTQLRGHRAPVSALCINELTGDIVSCAGT--YIHVWSIN 3180
            ++  +WD  K   L  +    +     C   + G +++       I +W + 
Sbjct: 574  KSVRLWDSVKGVALFSIEACHSRFVTCCAFSIDGTLLASGSMDRIIKIWKLT 729
>03387
          Length = 1891

 Score = 39.3 bits (90), Expect = 0.032,   Method: Compositional matrix adjust.
 Identities = 39/187 (20%), Positives = 82/187 (43%), Gaps = 13/187 (6%)
 Frame = +1

Query: 3071 NPKL---VITGGTSTVVCVWEMGTSKEKAKPLTLKQALLGHTDTVTCATASLAYHII--- 3124
            NP L   +++      +C+W++ +++ +++ +       GHT  V      +A+H++   
Sbjct: 388  NPNLNGHLLSASDDHTICLWDINSTQRESRVVDAHTIFTGHTSVV----EDVAWHLLHES 555

Query: 3125 --VSGSRDRTCIIWDL--NKLSFLTQ-LRGHRAPVSALCINELTGDIVSC--AGTYIHVW 3177
               S + D+  +IWD   N  S  +  +  H A V+ L  N  +  I++   A   + +W
Sbjct: 556  LFGSVADDQKLMIWDTRSNTTSKPSHVVDAHTAEVNCLSFNPYSEFILATGSADKTVALW 735

Query: 3178 SINGNPIVSVNTFTGRSQQIVCCCMSEMNEWDTQNVIVTGHSDGVVRFWRMEFLQVPETP 3237
             +  N  + +++F     +I     S  NE     ++ +  +D  +  W +   ++ E  
Sbjct: 736  DLR-NLKLKLHSFESHKDEIFQVQWSPHNE----TILASSGTDRRLHVWDLS--KIGEEQ 894

Query: 3238 APEPVED 3244
             PE  ED
Sbjct: 895  LPEDAED 915
>10264
          Length = 416

 Score = 38.9 bits (89), Expect = 0.040,   Method: Compositional matrix adjust.
 Identities = 30/101 (29%), Positives = 47/101 (46%), Gaps = 8/101 (7%)
 Frame = -1

Query: 3088 EMGTS-----KEKAKPLTLKQALLGHTDTVTCATASLAYHI-IVSGSRDRTCIIWDLNKL 3141
            EMG +     KE    LT  + L GH+  VT  + S  +   +VS   D    +WD+ K 
Sbjct: 323  EMGATEREGDKETLLILTSLRELSGHSQRVTDMSWSPHHDARLVSVGYDAEAFVWDVQKG 144

Query: 3142 SFLTQLRGHRAPVSALCINELTGDIVSCAGT--YIHVWSIN 3180
            + L Q +GH   +     + L  D+V   G+   +HVW ++
Sbjct: 143  TALAQFKGHMGRLLTCQFSGLDPDLVMTGGSDASVHVWRVS 21
>00561
          Length = 1003

 Score = 38.1 bits (87), Expect = 0.065,   Method: Composition-based stats.
 Identities = 29/109 (26%), Positives = 45/109 (41%)
 Frame = -3

Query: 3071 NPKLVITGGTSTVVCVWEMGTSKEKAKPLTLKQALLGHTDTVTCATASLAYHIIVSGSRD 3130
            NP ++++ G    V VW +   K       LK    GH   +   T S    +  SG +D
Sbjct: 569  NP-IIVSCGWDRTVKVWNLANCK-------LKNNHHGHNGYLNTVTVSPDGSLCTSGGKD 414

Query: 3131 RTCIIWDLNKLSFLTQLRGHRAPVSALCINELTGDIVSCAGTYIHVWSI 3179
               ++WDLN    L  L  H   ++ALC +     +    G  I +W +
Sbjct: 413  SKALLWDLNDGKNLYTLE-HNDIINALCFSPNRYWLCVAYGPSIKIWDL 270

 Score = 34.3 bits (77), Expect = 0.90,   Method: Composition-based stats.
 Identities = 34/159 (21%), Positives = 66/159 (41%), Gaps = 1/159 (0%)
 Frame = -3

Query: 3071 NPKLVITGGTSTVVCVWEMGTSKEKAKPLTLKQALLGHTDTVTCATASLAYHIIVSGSRD 3130
            +P  +I+      + VW++ T  E       ++ L GH+  ++    S   +  +SGS D
Sbjct: 977  DPDTIISASRDKTLIVWKL-TRDEDTNYGYPQKRLYGHSHFISDVVLSSDGNYALSGSWD 801

Query: 3131 RTCIIWDLNKLSFLTQLRGHRAPVSALCINELTGDIVSCA-GTYIHVWSINGNPIVSVNT 3189
            +T  +WDL       +  GH   V ++  +     IVS +    I +W+       ++  
Sbjct: 800  QTLRLWDLAAGKTTRRFEGHTKDVLSVAFSADNRQIVSGSRDKTIKLWNTLAECKFTIQE 621

Query: 3190 FTGRSQQIVCCCMSEMNEWDTQNVIVTGHSDGVVRFWRM 3228
              G +  + C   S  +   +  +IV+   D  V+ W +
Sbjct: 620  -DGHTDWVSCVRFSPNH---SNPIIVSCGWDRTVKVWNL 516
>01598
          Length = 1545

 Score = 37.7 bits (86), Expect = 0.080,   Method: Compositional matrix adjust.
 Identities = 27/91 (29%), Positives = 44/91 (48%), Gaps = 3/91 (3%)
 Frame = +1

Query: 3093 KEKAKPLTLKQALLGHTDTVTCATASLAYHI-IVSGSRDRTCIIWDLNKLSFLTQLRGHR 3151
            KE +  LT  + L GH+  VT  + S  +   +VS   D    +WD+ K + L Q +GH 
Sbjct: 1252 KETSLILTSLRELSGHSQRVTDMSWSPHHDARLVSVGYDAEAFVWDVQKGTALAQFKGHM 1431

Query: 3152 APVSALCINELTGDIVSCAGT--YIHVWSIN 3180
              +     + L  D+V   G+   +HVW ++
Sbjct: 1432 GRLLTCQFSGLDPDLVMTGGSDASVHVWRVS 1524
>17598
          Length = 875

 Score = 37.7 bits (86), Expect = 0.084,   Method: Composition-based stats.
 Identities = 18/74 (24%), Positives = 35/74 (47%)
 Frame = +1

Query: 3074 LVITGGTSTVVCVWEMGTSKEKAKPLTLKQALLGHTDTVTCATASLAYHIIVSGSRDRTC 3133
            LV++      + VW+  T       +TLK   +GH   +     +L  + + SGS+D   
Sbjct: 424  LVVSASMDKTIKVWDNQT-------MTLKHTFVGHKTQINAIDLALKTYYLASGSKDGIV 582

Query: 3134 IIWDLNKLSFLTQL 3147
            + W++   +FL ++
Sbjct: 583  MTWNIQNGTFLGKI 624

 Score = 35.0 bits (79), Expect = 0.55,   Method: Composition-based stats.
 Identities = 33/168 (19%), Positives = 71/168 (42%), Gaps = 4/168 (2%)
 Frame = +1

Query: 3073 KLVITGGTSTVVCVWEMGTSKEKAKPLTL---KQALLGHTDTVTCATASLAYHIIVSGSR 3129
            + +I GG   ++ VW++   K+  +  T    ++ L GH+  V+  + S     ++S S 
Sbjct: 4    EFLIXGGRDKLLIVWDLVPRKDGDEDETWGGPRRTLQGHSHFVSDVSLSADSRYVLSSSW 183

Query: 3130 DRTCIIWDLNKLSFLTQLRGHRAPVSALCINELTGDIVSCA-GTYIHVWSINGNPIVSVN 3188
            D T  +WD+ K +   +   H     A+  +     I S      + +W+  G    +V+
Sbjct: 184  DATLRLWDIKKGNTTRRFISHTRDALAVAFSPDNRQIASGGRDKALKIWNTVGECKFTVD 363

Query: 3189 TFTGRSQQIVCCCMSEMNEWDTQNVIVTGHSDGVVRFWRMEFLQVPET 3236
                 S Q    C+ + ++     ++V+   D  ++ W  + + +  T
Sbjct: 364  ---ANSHQDWVTCV-KFHQDAKSPLVVSASMDKTIKVWDNQTMTLKHT 495

 Score = 34.3 bits (77), Expect = 1.0,   Method: Composition-based stats.
 Identities = 23/98 (23%), Positives = 43/98 (43%), Gaps = 7/98 (7%)
 Frame = +1

Query: 3067 AVCPNPKLVITGGTSTVVCVWE-MGTSKEKAKPLTLKQALLGHTDTVTCATASLAYH--- 3122
            A  P+ + + +GG    + +W  +G  K      +       H D VTC    + +H   
Sbjct: 268  AFSPDNRQIASGGRDKALKIWNTVGECKFTVDANS-------HQDWVTC----VKFHQDA 414

Query: 3123 ---IIVSGSRDRTCIIWDLNKLSFLTQLRGHRAPVSAL 3157
               ++VS S D+T  +WD   ++      GH+  ++A+
Sbjct: 415  KSPLVVSASMDKTIKVWDNQTMTLKHTFVGHKTQINAI 528
>37180
          Length = 681

 Score = 36.2 bits (82), Expect = 0.24,   Method: Compositional matrix adjust.
 Identities = 25/88 (28%), Positives = 38/88 (43%)
 Frame = +1

Query: 3070 PNPKLVITGGTSTVVCVWEMGTSKEKAKPLTLKQALLGHTDTVTCATASLAYHIIVSGSR 3129
            P  +LV+T        +W+   S        L     GHT  VT A  + +   +VSGS 
Sbjct: 49   PTQRLVVTSSKDMTFRLWDFRDSA------LLVNVFQGHTQPVTSAVFA-SGDKVVSGSD 207

Query: 3130 DRTCIIWDLNKLSFLTQLRGHRAPVSAL 3157
            DRT  +WD         +R  R+P++ +
Sbjct: 208  DRTVRVWD---------MRNMRSPIATI 264

 Score = 31.6 bits (70), Expect = 6.6,   Method: Composition-based stats.
 Identities = 20/88 (22%), Positives = 38/88 (43%), Gaps = 3/88 (3%)
 Frame = +1

Query: 3105 LLGHTDTVTCATASLAYHIIVSGSRDRTCIIWDLNKLSFLTQL-RGHRAPVSALCINELT 3163
            L GH   ++   A     ++V+ S+D T  +WD    + L  + +GH  PV++       
Sbjct: 7    LNGHDQELSDVHAHPTQRLVVTSSKDMTFRLWDFRDSALLVNVFQGHTQPVTSAVFASGD 186

Query: 3164 GDIVSCAGTYIHVWSING--NPIVSVNT 3189
              +       + VW +    +PI ++ T
Sbjct: 187  KVVSGSDDRTVRVWDMRNMRSPIATIRT 270
>30295
          Length = 593

 Score = 36.2 bits (82), Expect = 0.25,   Method: Composition-based stats.
 Identities = 22/79 (27%), Positives = 38/79 (48%)
 Frame = +2

Query: 3059 SEWGQILCAVCPNPKLVITGGTSTVVCVWEMGTSKEKAKPLTLKQALLGHTDTVTCATAS 3118
            S W  + CA  P+   V  GG   +  ++ + T +   +   + + L GHT  ++C    
Sbjct: 371  SSW-VMTCAYAPSGGYVACGGLDNICSIYSLKTREGNVR---VSRELPGHTGYLSCCRF- 535

Query: 3119 LAYHIIVSGSRDRTCIIWD 3137
            +  + IV+ S D TC +WD
Sbjct: 536  IDDNQIVTSSGDMTCALWD 592
>16199
          Length = 694

 Score = 35.0 bits (79), Expect = 0.52,   Method: Composition-based stats.
 Identities = 15/50 (30%), Positives = 27/50 (54%)
 Frame = +2

Query: 3112 VTCATASLAYHIIVSGSRDRTCIIWDLNKLSFLTQLRGHRAPVSALCINE 3161
            +TCA       I  +G+ D    IWDL + + +   +GH+ PV+++  +E
Sbjct: 80   LTCAQFHPDGLIFATGTEDSVIKIWDLKERANVANFQGHQGPVTSISFSE 229
>03734
          Length = 1963

 Score = 34.3 bits (77), Expect = 0.85,   Method: Compositional matrix adjust.
 Identities = 22/74 (29%), Positives = 37/74 (50%), Gaps = 1/74 (1%)
 Frame = -2

Query: 3101 LKQALLGHTDTVTCATASLAYHIIVSG-SRDRTCIIWDLNKLSFLTQLRGHRAPVSALCI 3159
            L++ ++G  DT     A L    IVSG SR + C  W+  + + +   + H+A V  LC 
Sbjct: 1920 LQRIIIGGEDTTVWCLAVLGDLTIVSGDSRGKVCF-WNGKQGTRIAHFQSHKADVLTLCA 1744

Query: 3160 NELTGDIVSCAGTY 3173
            +E   ++  C G +
Sbjct: 1743 DESETNVF-CGGVH 1705
>19949
          Length = 903

 Score = 33.9 bits (76), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 19/51 (37%), Positives = 23/51 (45%)
 Frame = +2

Query: 3107 GHTDTVTCATASLAYHIIVSGSRDRTCIIWDLNKLSFLTQLRGHRAPVSAL 3157
            GHT  V C   S     I S S D    +WDL     LT L+ HR  V+ +
Sbjct: 113  GHTGCVCCLRFSPDGRWIASASEDGLVKLWDLTAGKLLTDLKLHRDAVNTI 265

 Score = 32.0 bits (71), Expect = 4.1,   Method: Compositional matrix adjust.
 Identities = 29/136 (21%), Positives = 51/136 (37%), Gaps = 13/136 (9%)
 Frame = +2

Query: 3118 SLAYH----IIVSGSRDRTCIIWDLNKLSFLTQLRGHRAPVSALCINELTGDIVSCA-GT 3172
            SL +H       SGS D    +WD+ +   +   +GH   V  L  +     I S +   
Sbjct: 8    SLDFHPYGAYTASGSMDCNVKLWDIRRKGCIYTYKGHTGCVCCLRFSPDGRWIASASEDG 187

Query: 3173 YIHVWSINGNPIVS--------VNTFTGRSQQIVCCCMSEMNEWDTQNVIVTGHSDGVVR 3224
             + +W +    +++        VNT      +                ++ +G +D  V+
Sbjct: 188  LVKLWDLTAGKLLTDLKLHRDAVNTIEFHPHEF---------------LLASGSADRTVK 322

Query: 3225 FWRMEFLQVPETPAPE 3240
            FW +E  Q+  T  PE
Sbjct: 323  FWDLETFQLISTTEPE 370

 Score = 31.2 bits (69), Expect = 6.8,   Method: Compositional matrix adjust.
 Identities = 22/108 (20%), Positives = 41/108 (37%), Gaps = 1/108 (0%)
 Frame = +2

Query: 3039 LSCRLGTYESDKAVTVYECLSEWGQILC-AVCPNPKLVITGGTSTVVCVWEMGTSKEKAK 3097
            + C +  ++  +   +Y      G + C    P+ + + +     +V +W++   K    
Sbjct: 53   MDCNVKLWDIRRKGCIYTYKGHTGCVCCLRFSPDGRWIASASEDGLVKLWDLTAGK---- 220

Query: 3098 PLTLKQALLGHTDTVTCATASLAYHIIVSGSRDRTCIIWDLNKLSFLT 3145
               L   L  H D V          ++ SGS DRT   WDL     ++
Sbjct: 221  ---LLTDLKLHRDAVNTIEFHPHEFLLASGSADRTVKFWDLETFQLIS 355
>06775
          Length = 489

 Score = 32.7 bits (73), Expect = 2.3,   Method: Compositional matrix adjust.
 Identities = 33/116 (28%), Positives = 55/116 (47%), Gaps = 2/116 (1%)
 Frame = +1

Query: 1419 AMASDVEGLYAAVKALVCVVKSNPLASKEMERIKGYQLLAMLLKKKRSLLNSHILHLTFS 1478
            A + D+EG   A  AL+ VV  N     + +R K  Q+              H  HLT  
Sbjct: 157  ANSCDIEGASFA*WALILVVGENKGRK*QAQRPKLPQV--------------HTAHLTLI 294

Query: 1479 LVGTVDSGHETSIIPNSTAFQDLLCDFEVWLHAPYELHLSLFEHF--IELLTESSE 1532
             + TV SG  TS++ + ++   +LC   + L AP ++  S+  H+  I +L +++E
Sbjct: 295  AISTVLSGDWTSLVWSRSSLVCVLCVLPL-LVAPGKIIASISAHYSTITMLFKATE 459
>15780
          Length = 735

 Score = 32.7 bits (73), Expect = 2.5,   Method: Composition-based stats.
 Identities = 20/69 (28%), Positives = 30/69 (43%)
 Frame = -1

Query: 3073 KLVITGGTSTVVCVWEMGTSKEKAKPLTLKQALLGHTDTVTCATASLAYHIIVSGSRDRT 3132
            K + T G    V VW++ +    A        L  HTDTV     S    ++ SG  D +
Sbjct: 735  KYLSTAGADHTVIVWDIASGTAVAH-------LTAHTDTVYALCFSRDGTVLASGGMDNS 577

Query: 3133 CIIWDLNKL 3141
              +WDL ++
Sbjct: 576  IRLWDLARV 550
>12574
          Length = 521

 Score = 32.7 bits (73), Expect = 2.6,   Method: Composition-based stats.
 Identities = 29/128 (22%), Positives = 52/128 (40%), Gaps = 1/128 (0%)
 Frame = +3

Query: 3091 TSKEKAKPLTLKQALLGHTDTVTCATASLAYHIIVSGSRDRTCIIWDLNKLSFLTQLRGH 3150
            +S  +    TLK  L GHT  ++    S     + S S D+   IW      F   + GH
Sbjct: 132  SSATQKPTYTLKFTLAGHTKALSAVKFSPNGDWLASSSADKLIKIWGAYDGKFEKTIAGH 311

Query: 3151 RAPVSALCINELTGDIVSCA-GTYIHVWSINGNPIVSVNTFTGRSQQIVCCCMSEMNEWD 3209
            +  +S +  +  +  + S +    + +W  +      + T  G S  + CC  +  +   
Sbjct: 312  KLGLSDVAWSSDSKLLCSASDDKTLKIWEFSTGK--CMKTLKGHSNYVFCCNFNPQS--- 476

Query: 3210 TQNVIVTG 3217
              N+IV+G
Sbjct: 477  --NLIVSG 494
>22415
          Length = 1099

 Score = 32.3 bits (72), Expect = 3.6,   Method: Composition-based stats.
 Identities = 26/80 (32%), Positives = 34/80 (42%), Gaps = 2/80 (2%)
 Frame = -2

Query: 779 SFDSHAEQIPPC--LTSESSLPSPWGTPALSRKRHAFHCVSTPPVYPAKNVTDLKLQVTS 836
           SF  H+  I P   L S S  P+PWG   L R +  F   +         V DL L   S
Sbjct: 939 SFLLHSAHIYPLHNLFSLSMSPTPWGCFNLRRNQKYFKISNIETTSIMN*V*DLHLLTNS 760

Query: 837 SPLQSSDAVIIHPGAMLAML 856
           + LQ    +I HP   + +L
Sbjct: 759 NELQFLHYII*HPKKFIFIL 700
>17266
          Length = 480

 Score = 32.3 bits (72), Expect = 3.7,   Method: Composition-based stats.
 Identities = 18/56 (32%), Positives = 26/56 (46%), Gaps = 4/56 (7%)
 Frame = -1

Query: 3110 DTVTCATASLAY----HIIVSGSRDRTCIIWDLNKLSFLTQLRGHRAPVSALCINE 3161
            D + C   S+A+     +++ G  D  C IWD+ K      L GH   VS L + E
Sbjct: 210  DNIICGITSVAFSKSGRLLLGGYDDFNCNIWDVLKQERTGVLAGHDNRVSCLGVTE 43
>26107
          Length = 1338

 Score = 32.0 bits (71), Expect = 4.8,   Method: Compositional matrix adjust.
 Identities = 22/77 (28%), Positives = 38/77 (49%), Gaps = 4/77 (5%)
 Frame = -3

Query: 3064 ILCAVCPNPKLVITGGTSTVVCVWEMGTSKEKAKPLTLKQALLGHTDTVT----CATASL 3119
            + CA+ P+ K +++G       +WE+   K   +PL     L+GHT+ V+    C+T   
Sbjct: 412  VRCAISPDGKYLLSGSGRNTGVIWEV--DKPNKRPL----FLIGHTEDVSAVDWCSTDVC 251

Query: 3120 AYHIIVSGSRDRTCIIW 3136
                + + S DR+  IW
Sbjct: 250  K---LATVSDDRSLRIW 209
>01249
          Length = 1743

 Score = 31.6 bits (70), Expect = 5.5,   Method: Compositional matrix adjust.
 Identities = 14/37 (37%), Positives = 22/37 (59%)
 Frame = -1

Query: 3102 KQALLGHTDTVTCATASLAYHIIVSGSRDRTCIIWDL 3138
            ++ L GH+D VTC   S     + SGS++   IIW++
Sbjct: 936  ERVLQGHSDAVTCLAFSSDGQRLASGSQNGKVIIWNM 826
>19140
          Length = 573

 Score = 31.2 bits (69), Expect = 8.3,   Method: Compositional matrix adjust.
 Identities = 24/76 (31%), Positives = 32/76 (42%)
 Frame = -3

Query: 3105 LLGHTDTVTCATASLAYHIIVSGSRDRTCIIWDLNKLSFLTQLRGHRAPVSALCINELTG 3164
            L GHTD V     +      +SGS D T  +W L +   +   R H   V AL  NE   
Sbjct: 499  LKGHTDNVKALVLNRDGTQCLSGSSDGTIRLWSLGQQRCVATFRVHDEGVWALQANESFT 320

Query: 3165 DIVSCAGTYIHVWSIN 3180
             + S  G    VW+ +
Sbjct: 319  TLYS-GGRDHQVWATD 275
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|58037415|ref|NP_083586.1| fatty acid binding protein
12 [Mus musculus]
         (132 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

07957                                                                  57   3e-09
14358                                                                  44   2e-05
31753                                                                  38   0.001
34917                                                                  30   0.40 
38549                                                                  29   0.47 
38888                                                                  29   0.71 
>07957
          Length = 883

 Score = 56.6 bits (135), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 41/132 (31%), Positives = 61/132 (46%)
 Frame = +1

Query: 1   MVDQLQGTWKSVSCDNFENYMKELGVGRASRKLGCLAKPTVTISTDGDLITIKTKSIFKN 60
           M D L G W+SVS +N +     +GV  A R+     K  +TI  DG    + T +  K+
Sbjct: 259 MADGLIGKWQSVSYENMDPLWDVMGVPDAMRQFARDKKTELTIEKDGGQWKLTTVAGDKS 438

Query: 61  KEISFKLGEEFEETTPSGRKSKSTVILDNDSLVQVQDWDGKEATICRRLVDGKMVVESAV 120
           + I F +G+E +  T  G   K+ +  +   LV+ Q     E  I R L DGK+     +
Sbjct: 439 RVIVFPVGQEVDTITLMGEPVKAILTEEGGQLVERQKAGVGEIIIQRSLQDGKLKTNMTL 618

Query: 121 NNVTCTRTYQRV 132
             VT    + RV
Sbjct: 619 KGVTAGIFFDRV 654
>14358
          Length = 996

 Score = 43.9 bits (102), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 31/99 (31%), Positives = 49/99 (49%), Gaps = 7/99 (7%)
 Frame = +1

Query: 41  VTISTDGDLITIKTKSIFKNKEISFKLGEEFEETTP-SGRKSKSTVILDNDSL----VQV 95
           + +  DG ++ I+T S F   E+SFKL EE+EE  P S +K  +    +N  L       
Sbjct: 7   IEVQDDGKIV-IRTNSTFMKSEVSFKLNEEYEEINPHSKKKFXNMPTYENGKLRVTPTPA 183

Query: 96  QDWDGKEATICRRLV--DGKMVVESAVNNVTCTRTYQRV 132
           +  D        R +  DG+M+V   V +V C R +++V
Sbjct: 184 EPIDVPYPEYXEREITDDGEMLVTLKVEDVXCKRWFKKV 300
>31753
          Length = 374

 Score = 38.1 bits (87), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 25/64 (39%), Positives = 32/64 (50%), Gaps = 5/64 (7%)
 Frame = -3

Query: 5   LQGTWKSVSCDNFENYMKELGV-GRASRKLGCLAKPTVT----ISTDGDLITIKTKSIFK 59
           L G WK VS DNFE+Y+  +GV G    K   L  P       I+ DGD I+I T +   
Sbjct: 219 LNGKWKLVSVDNFESYLDAVGVQGEFRDKALKLLTPENNILQDIAIDGDAISITTTTPIA 40

Query: 60  NKEI 63
             E+
Sbjct: 39  PIEV 28
>34917
          Length = 352

 Score = 29.6 bits (65), Expect = 0.40,   Method: Compositional matrix adjust.
 Identities = 12/19 (63%), Positives = 14/19 (73%)
 Frame = +2

Query: 92  LVQVQDWDGKEATICRRLV 110
           LVQVQ WD K AT+  RL+
Sbjct: 239 LVQVQSWDVKAATLTHRLL 295
>38549
          Length = 797

 Score = 29.3 bits (64), Expect = 0.47,   Method: Compositional matrix adjust.
 Identities = 14/46 (30%), Positives = 25/46 (54%)
 Frame = -1

Query: 55  KSIFKNKEISFKLGEEFEETTPSGRKSKSTVILDNDSLVQVQDWDG 100
           + I + KE  FK+    E+T P GR+++  +  +N  L+ +  W G
Sbjct: 506 QPIVRKKETGFKV----EQTDPHGRRAREKLAQNNTHLLTLIQW*G 381
>38888
          Length = 370

 Score = 28.9 bits (63), Expect = 0.71,   Method: Compositional matrix adjust.
 Identities = 18/56 (32%), Positives = 26/56 (46%), Gaps = 3/56 (5%)
 Frame = +3

Query: 75  TPSGRKSKSTVILDNDSLVQVQDWDGKEATICRRL---VDGKMVVESAVNNVTCTR 127
           TPS  + K    ++ D  V+ +DW G    I RRL      K +V ++   V C R
Sbjct: 180 TPSS*RRKREEAVEEDRTVEEEDWSGTRRGIERRLRGAASDKCLVSTSCCCVACCR 347
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6678355|ref|NP_033412.1| tight junction protein 1
[Mus musculus]
         (1745 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

17179                                                                  61   4e-09
08480                                                                  49   3e-05
29974                                                                  45   3e-04
03831                                                                  43   0.001
02951                                                                  41   0.004
01502                                                                  41   0.004
38751                                                                  38   0.044
13104                                                                  37   0.078
13641                                                                  35   0.34 
27345                                                                  33   1.4  
37239                                                                  31   5.4  
>17179
          Length = 523

 Score = 61.2 bits (147), Expect = 4e-09,   Method: Composition-based stats.
 Identities = 34/78 (43%), Positives = 41/78 (52%), Gaps = 19/78 (24%)
 Frame = +1

Query: 1687 GETLLSPLVMCGPHGLKFLKPVELRLPHCDPKT-------------------WQNKCLPG 1727
            GET+LSPLVMCGP GL+FL PV L +PHC  +T                   W N  LP 
Sbjct: 1    GETMLSPLVMCGPQGLEFLVPVTLNIPHCAGRTASLGLALKATDSEKNLHTEWDNIDLPS 180

Query: 1728 DPNYLVGANCVSVLIDHF 1745
            +      A+ VSV +DHF
Sbjct: 181  N----AAAHTVSVKVDHF 222
>08480
          Length = 698

 Score = 48.5 bits (114), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 46/146 (31%), Positives = 67/146 (45%), Gaps = 24/146 (16%)
 Frame = -1

Query: 461 LEEGDQILRVNNVDFTNIIREEAVLFLLDLPKGEEVTILAQKKKDVYRRIVESDVGD--- 517
           L  GD+IL VN+VD      E+A   L     G+ V I+AQ K + Y R  E+ + D   
Sbjct: 674 LRRGDKILSVNDVDVERATHEQAAQALK--RAGDTVEIIAQYKPEDYNRF-EAKIQDLRE 504

Query: 518 ----------------SFYIRTHFEYE--KESPY---GLSFNKGEVFRVVDTLYNGKLGS 556
                           + ++R  F+YE  K+S     GL F+ G++  V +   +     
Sbjct: 503 QMMNNSAGSLRTTQKRTMFVRALFDYEPSKDSGLPSRGLWFHYGDILHVTNASDDE---W 333

Query: 557 WLAIRIGKNHKEVERGIIPNKNRAEQ 582
           W A RI  + KE   GIIP+K R E+
Sbjct: 332 WQAKRILPDGKEEGMGIIPSKRRVER 255
>29974
          Length = 344

 Score = 45.1 bits (105), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 16/38 (42%), Positives = 27/38 (71%)
 Frame = +1

Query: 693 TIKQIIDQDKHALLDVTPNAVDRLNYAQWYPIVVFLNP 730
           ++K++ +Q +H +LDV+ NA+ RL  A  YPI +F+ P
Sbjct: 202 SVKEVAEQGRHCILDVSGNAIKRLQVAGLYPIAIFIKP 315
>03831
          Length = 1143

 Score = 42.7 bits (99), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 62/281 (22%), Positives = 107/281 (38%), Gaps = 19/281 (6%)
 Frame = +3

Query: 22  HTVTLHRAPGFGFGIAISGGRDNPHFQSGETSIVISDVLKGGPAEGQ-LQENDRVAMVNG 80
           H V      G+GF         N H + G+    I  V +G PAE   L+  DR+  VNG
Sbjct: 141 HIVRWSDFNGYGF---------NLHAEKGKAGQFIGKVDEGSPAEAAGLKAGDRIVEVNG 293

Query: 81  VSMDNVEHAFAVQQLRKSGKNAKITIRRKKKVQIPVSHPDPEPVSDNEDDSYDEEVHDPR 140
            ++ N  H   V +++  G   ++ +                 V    D  Y EE    R
Sbjct: 294 TNIGNENHQQVVGRIKAGGDETRLLV-----------------VDQETDQHYKEE---KR 413

Query: 141 AGRGALANRR--SEKSWARDRSASRERSLSPRSDRRSVASSQPAK---------PTKVTL 189
             RG L   R  +     +D   ++E  ++   +  +    +P           P    L
Sbjct: 414 VVRGDLPETRFMTAAREQKDNXENQEAEIAAVVEATNGTEPEPQSLPDESSLYAPRLCHL 593

Query: 190 VKSRKNEEYGL-------RPASHIFVKEISQDSLAARDGDIQEGDVVLKINGTVTENMSL 242
            K    + YG        +P    ++  +  +S  A  G ++EGD ++++NG   EN+  
Sbjct: 594 CKWADFDGYGFNLHAEKDKPGQ--YIGSVDPNS-PAETGGLKEGDRIIEVNG---ENIET 755

Query: 243 TDAKTLIERSKGKLKMVVQRDERATLLNVPDLSDSIHSANA 283
           T+   +I+  K        R ++ ++L V   +DS +   A
Sbjct: 756 TNHTAVIQNIK-------SRGDKTSMLVVDKAADSYYKNRA 857

 Score = 33.9 bits (76), Expect = 0.55,   Method: Compositional matrix adjust.
 Identities = 22/57 (38%), Positives = 31/57 (54%), Gaps = 3/57 (5%)
 Frame = +3

Query: 424 LVKFRKGDSVGLRLAGGNDV-GIFVAGVLEDSPAAKEGLEEGDQILRVN--NVDFTN 477
           L K+   D  G  L    D  G ++  V  +SPA   GL+EGD+I+ VN  N++ TN
Sbjct: 591 LCKWADFDGYGFNLHAEKDKPGQYIGSVDPNSPAETGGLKEGDRIIEVNGENIETTN 761

 Score = 33.1 bits (74), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 19/55 (34%), Positives = 28/55 (50%), Gaps = 1/55 (1%)
 Frame = +3

Query: 424 LVKFRKGDSVGLRL-AGGNDVGIFVAGVLEDSPAAKEGLEEGDQILRVNNVDFTN 477
           +V++   +  G  L A     G F+  V E SPA   GL+ GD+I+ VN  +  N
Sbjct: 144 IVRWSDFNGYGFNLHAEKGKAGQFIGKVDEGSPAEAAGLKAGDRIVEVNGTNIGN 308
>02951
          Length = 1076

 Score = 41.2 bits (95), Expect = 0.004,   Method: Composition-based stats.
 Identities = 21/46 (45%), Positives = 32/46 (69%)
 Frame = +2

Query: 439 GGNDVGIFVAGVLEDSPAAKEGLEEGDQILRVNNVDFTNIIREEAV 484
           G  D GI+V  + E+SPAA+ GL+  D+IL++N  DFT +  ++AV
Sbjct: 5   GYPDKGIYVTFIYENSPAARCGLQLHDKILQLNGKDFTVVTHKQAV 142
>01502
          Length = 1949

 Score = 41.2 bits (95), Expect = 0.004,   Method: Composition-based stats.
 Identities = 20/43 (46%), Positives = 31/43 (72%)
 Frame = +1

Query: 442 DVGIFVAGVLEDSPAAKEGLEEGDQILRVNNVDFTNIIREEAV 484
           D GI+V  + E+SPAA+ GL+  D+IL++N  DFT +  ++AV
Sbjct: 28  DKGIYVTFIYENSPAARCGLQLHDKILQLNGKDFTVVTHKQAV 156
>38751
          Length = 329

 Score = 37.7 bits (86), Expect = 0.044,   Method: Composition-based stats.
 Identities = 23/57 (40%), Positives = 33/57 (57%), Gaps = 2/57 (3%)
 Frame = +3

Query: 433 VGLRLAGGNDVG--IFVAGVLEDSPAAKEGLEEGDQILRVNNVDFTNIIREEAVLFL 487
           VG++  GG + G  I V  + E   A ++GL  GD+IL VN  DFT++   EAV  +
Sbjct: 3   VGIK--GGKEYGTPIVVYVIEEGCQAEQQGLNIGDRILDVNGTDFTHLTHAEAVTIM 167
>13104
          Length = 1094

 Score = 37.0 bits (84), Expect = 0.078,   Method: Compositional matrix adjust.
 Identities = 26/84 (30%), Positives = 39/84 (46%), Gaps = 1/84 (1%)
 Frame = -2

Query: 1635 GIFNSNGGVLSSIETGVSIIIPQGAIPEGIEQEIYFKVCRD-NSILPPLDKEKGETLLSP 1693
            G F S GG L   ++ V + + +GAI +G   EI   V  D  +    L   + E +  P
Sbjct: 625  GQFTSVGGCLQGKDSDVVLKVTRGAITKGDFLEIRGAVSTDLMTAHKRLKLPESEMIACP 446

Query: 1694 LVMCGPHGLKFLKPVELRLPHCDP 1717
            L+        F+ P+E+ LPH  P
Sbjct: 445  LIEYDASDAVFITPLEICLPHFVP 374
>13641
          Length = 2081

 Score = 34.7 bits (78), Expect = 0.34,   Method: Compositional matrix adjust.
 Identities = 32/126 (25%), Positives = 54/126 (42%), Gaps = 10/126 (7%)
 Frame = +2

Query: 691 LHTIKQIIDQDKHALLDVTPNAVDRLNYAQWYPIVVFLNPDSKQGVKTMRM--------- 741
           + +IKQ+I   K  LL     A+  L   +  P V+F+   + + +K  RM         
Sbjct: 803 VESIKQVIAAGKVCLLTPHTQALKFLRTYELKPYVIFIKSPTLEKLKESRMPARARATEA 982

Query: 742 -RLCPESRKSARKLYERSHKLRKNNHHLFTTTINLNSMNDGWYGALKEAIQQQQNQLVWV 800
             + P S +   ++ E S +L +   H+F  TI  +S+ D     L  A + ++N     
Sbjct: 983 DSIRPFSIEELEEMAETSRRLEERYGHVFDITIVNDSLTDATTELLMVASK*RKNHSGCR 1162

Query: 801 SEGKAD 806
           S G  D
Sbjct: 1163SVGDND 1180
>27345
          Length = 496

 Score = 32.7 bits (73), Expect = 1.4,   Method: Composition-based stats.
 Identities = 17/67 (25%), Positives = 36/67 (53%), Gaps = 1/67 (1%)
 Frame = +3

Query: 199 GLRPAS-HIFVKEISQDSLAARDGDIQEGDVVLKINGTVTENMSLTDAKTLIERSKGKLK 257
           G RP    IF+K ++    A +DG IQ  D +++++G     ++   A +++  + G++ 
Sbjct: 3   GCRPGKLGIFIKTLTDGGAAQKDGRIQVNDQIIEVDGKSLVGVTQAYAASVLRNTSGQVT 182

Query: 258 MVVQRDE 264
             + RD+
Sbjct: 183 FHIGRDK 203
>37239
          Length = 453

 Score = 30.8 bits (68), Expect = 5.4,   Method: Compositional matrix adjust.
 Identities = 18/50 (36%), Positives = 27/50 (54%), Gaps = 1/50 (2%)
 Frame = -2

Query: 214 DSLAARDGDIQEGDVVLKINGTVTENMSLTDAKTLIERSKG-KLKMVVQR 262
           DS AARD  I  GD +L+ING +       +A  +++      +K+VV R
Sbjct: 446 DSPAARDARIHVGDELLEINGNLLHGRCHLNASAIVKSVTAPDVKLVVNR 297
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|33636693|ref|NP_891846.1| pleckstrin homology domain
containing, family A member 6 [Mus musculus]
         (1173 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

29521                                                                  60   5e-09
13952                                                                  53   8e-07
03368                                                                  44   4e-04
29667                                                                  41   0.003
15376                                                                  39   0.010
19246                                                                  37   0.055
25051                                                                  36   0.086
27925                                                                  36   0.11 
11159                                                                  34   0.43 
33078                                                                  32   2.1  
29522                                                                  31   2.4  
05879                                                                  30   4.4  
>29521
          Length = 903

 Score = 60.1 bits (144), Expect = 5e-09,   Method: Composition-based stats.
 Identities = 32/79 (40%), Positives = 44/79 (55%), Gaps = 1/79 (1%)
 Frame = +1

Query: 80  RWFVL-VDRCLFYYKDEKQESILGSIPLLSFRVAAVQPSDNISRKHTFKAEHAGVRTYFF 138
           R+F+L  D CL+YYK  +    LG+IPL  +  +    S    R   FKAE  G RTY+F
Sbjct: 1   RYFILRQDSCLYYYKQREDSDPLGAIPLAGYTFSRHLDS---GRDFCFKAEKYGARTYYF 171

Query: 139 SAESPEEQEAWIQAMGEAA 157
             ES ++   W+ A+ EAA
Sbjct: 172 MTESRDDMTEWVGALSEAA 228

 Score = 34.7 bits (78), Expect(2) = 4e-05,   Method: Compositional matrix adjust.
 Identities = 12/28 (42%), Positives = 19/28 (67%)
 Frame = +3

Query: 75  KQWNKRWFVLVDRCLFYYKDEKQESILG 102
           + W++R+ +L D CL+YYK+    S LG
Sbjct: 351 RTWHRRYCILKDACLYYYKNMNSLSALG 434

 Score = 32.0 bits (71), Expect(2) = 4e-05,   Method: Compositional matrix adjust.
 Identities = 15/42 (35%), Positives = 25/42 (59%), Gaps = 2/42 (4%)
 Frame = +2

Query: 114 VQPSDNISRKHTFKAE--HAGVRTYFFSAESPEEQEAWIQAM 153
           V PS ++ +KH F        +RT+ FSAE+  +++ W+ AM
Sbjct: 458 VDPSISVGKKHAFGVVPPVDALRTFQFSAENDTDRQRWVDAM 583
>13952
          Length = 577

 Score = 52.8 bits (125), Expect = 8e-07,   Method: Compositional matrix adjust.
 Identities = 38/114 (33%), Positives = 51/114 (44%), Gaps = 21/114 (18%)
 Frame = -3

Query: 61  TKAGWLYKQASSGVKQWNKRWFVLVDRCLFYYKDEKQESILGSIPL-------LS----- 108
            K GWL KQ     K W +RWF+L D CL+Y++    +   G IPL       LS     
Sbjct: 419 VKEGWLMKQGGR-YKNWKRRWFILNDNCLYYFQYTADKEPKGIIPLENIQVRELSEKSSR 243

Query: 109 ---FRVAAVQPSDNI------SRKHTFKAEHAGVRTYFFSAESPEEQEAWIQAM 153
              F + +V  SD I      S     +  H+    Y  SA S EE +AWI ++
Sbjct: 242 SNAFELYSVSGSDVIKACKVDSDGKVVEGRHS---VYRMSASSAEEMDAWISSI 90
>03368
          Length = 1677

 Score = 43.9 bits (102), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 36/90 (40%), Positives = 55/90 (61%), Gaps = 2/90 (2%)
 Frame = -2

Query: 1043 LSTPDKVLIPERYIDLEPDTPLSPEELK-EKQKKVERIKTLIAKSSMQNVVPIGEGDSVD 1101
            L  P+KVLIPERY D E D  L  E+ + E+Q+K ERIK ++A    Q+V+ + + D   
Sbjct: 1226 LYFPEKVLIPERY-DAEADAELLTEDQRVERQEKAERIKRILAN---QSVLSMSQPDLNP 1059

Query: 1102 VPQDSESQL-QEQEKRIEISCALATEASRR 1130
            V  +  ++L QE+ +R+ I  AL  E +R+
Sbjct: 1058 VSPELHTRLEQEKAQRVHI-LALNQELARQ 972
>29667
          Length = 466

 Score = 40.8 bits (94), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 20/57 (35%), Positives = 27/57 (47%)
 Frame = +1

Query: 101 LGSIPLLSFRVAAVQPSDNISRKHTFKAEHAGVRTYFFSAESPEEQEAWIQAMGEAA 157
           L S+PLL + V    P D I + H FK +      YFF AES      W++ +  A 
Sbjct: 28  LASLPLLGYAVNQPDPDDGIGKDHVFKLQFKN-HVYFFRAESEYTYSRWMEVINSAT 195
>15376
          Length = 712

 Score = 39.3 bits (90), Expect = 0.010,   Method: Compositional matrix adjust.
 Identities = 30/95 (31%), Positives = 42/95 (44%), Gaps = 21/95 (22%)
 Frame = +1

Query: 80  RWFVLVDRCLFYYKDEKQESILGSIPL-------LS--------FRVAAVQPSDNI---- 120
           RWF+L D CL+Y++    +   G IPL       LS        F + +V  SD I    
Sbjct: 1   RWFILNDNCLYYFQYTADKEPKGIIPLENIQVRELSEKSSRSNAFELYSVSGSDVIKACK 180

Query: 121 --SRKHTFKAEHAGVRTYFFSAESPEEQEAWIQAM 153
             S     +  H+    Y  SA S EE +AWI ++
Sbjct: 181 VDSDGKVVEGRHS---VYRMSASSAEEMDAWISSI 276
>19246
          Length = 440

 Score = 36.6 bits (83), Expect = 0.055,   Method: Compositional matrix adjust.
 Identities = 28/99 (28%), Positives = 38/99 (38%), Gaps = 10/99 (10%)
 Frame = +2

Query: 65  WLYKQASSGVK----QWNKRWFVLVDRCLFYYKDEKQESILGSI----PLLSFRVAAVQP 116
           W     S G K     W + W VL    LF  KD +  S   +     P +S +   V  
Sbjct: 20  WCKTAVSDGKKCSDRSWKQVWAVLRGHALFLIKDRRDGSTHPTFSFEEPPISIKSCLVDI 199

Query: 117 SDNISRK--HTFKAEHAGVRTYFFSAESPEEQEAWIQAM 153
           + + SRK  H F+        Y   AE      +WIQA+
Sbjct: 200 AHDYSRKRKHVFRLTTYSESVYLLQAEDKGTMMSWIQAI 316
>25051
          Length = 1017

 Score = 36.2 bits (82), Expect = 0.086,   Method: Compositional matrix adjust.
 Identities = 27/97 (27%), Positives = 43/97 (44%), Gaps = 6/97 (6%)
 Frame = -2

Query: 73  GVKQWNKRWFVLVDRCLFYYKDEKQ----ESILGSIPLLSFRVA-AVQPSDNISRKHTFK 127
           G + W   + +L D  L+ YKDE Q    + +  S  ++    A A + SD   ++H F+
Sbjct: 848 GKRGWRMVYTILRDLILYQYKDEHQVKKGQFVESSQNVVRIHHALATKASDYTKKQHVFR 669

Query: 128 AEHAGVRTYFFSAESPEEQEAWIQAMG-EAARVQIPP 163
            + A    Y F      E + WI  +   AA +  PP
Sbjct: 668 LQTADWAEYLFQTGGTIELQEWIDTINLVAATLSSPP 558
>27925
          Length = 370

 Score = 35.8 bits (81), Expect = 0.11,   Method: Composition-based stats.
 Identities = 20/64 (31%), Positives = 35/64 (54%), Gaps = 1/64 (1%)
 Frame = +3

Query: 69  QASSGVKQWNKRWFVL-VDRCLFYYKDEKQESILGSIPLLSFRVAAVQPSDNISRKHTFK 127
           + +   K+W +RWF L  D CL+YYK E     +G++ +++     + P D I +   FK
Sbjct: 3   KGAPNTKKWVRRWFSLRPDNCLYYYKTEDDSQPVGAM-IMAKHTVELCPID-IGKPFGFK 176

Query: 128 AEHA 131
            E++
Sbjct: 177 VEYS 188
>11159
          Length = 520

 Score = 33.9 bits (76), Expect = 0.43,   Method: Compositional matrix adjust.
 Identities = 22/104 (21%), Positives = 42/104 (40%), Gaps = 8/104 (7%)
 Frame = +2

Query: 73  GVKQWNKRWFVLVDRCLFYYKDEK-------QESILGSIPLLSFRVAAVQPSDNISRKHT 125
           G + W   +  L D  L+ +KDE         +++  +I +      A   +D   ++H 
Sbjct: 59  GKRSWKMFFITLRDLVLYLHKDEHGFRKSQMSDNLHNAIRI--HHALATMANDYTKKQHV 232

Query: 126 FKAEHAGVRTYFFSAESPEEQEAWIQAMGE-AARVQIPPAQKSV 168
           F+ + A    Y F     +E  +W++ +    A    PP +  V
Sbjct: 233 FRLQTADQAEYLFQTSDSKELHSWVETINYVCAAFSAPPLEAGV 364
>33078
          Length = 243

 Score = 31.6 bits (70), Expect = 2.1,   Method: Compositional matrix adjust.
 Identities = 17/50 (34%), Positives = 24/50 (48%), Gaps = 1/50 (2%)
 Frame = -2

Query: 62  KAGWLYKQASSGVKQ-WNKRWFVLVDRCLFYYKDEKQESILGSIPLLSFR 110
           + G+LYKQ      Q W  RW V   + L YY + + +     IPL S +
Sbjct: 155 RYGYLYKQGGIKANQGWRMRWVVFNGKDLRYYDNNRSQISKKIIPLSSMK 6
>29522
          Length = 698

 Score = 31.2 bits (69), Expect = 2.4,   Method: Composition-based stats.
 Identities = 19/54 (35%), Positives = 27/54 (50%), Gaps = 1/54 (1%)
 Frame = -3

Query: 49  AHSMKRNPNAPVTKAGWLYKQASSGVKQWNKR-WFVLVDRCLFYYKDEKQESIL 101
           + S KR     V + GWL     S +K  +K  WFVL    L ++KDE+   +L
Sbjct: 213 SQSSKRKMGNQVIRKGWLSLHNISFIKGGSKDFWFVLTAESLSWFKDEEVSFLL 52
>05879
          Length = 713

 Score = 30.4 bits (67), Expect = 4.4,   Method: Compositional matrix adjust.
 Identities = 34/132 (25%), Positives = 58/132 (43%), Gaps = 26/132 (19%)
 Frame = +2

Query: 51  SMKRNPNAPVTKAGWLYK-QASSGVKQWNKRWFVLVDRCLFYYK---DEKQESILGSIPL 106
           ++K    A V + G+L   +  SG+  W++RW  L    L Y+K   DE ++  +G I L
Sbjct: 128 NLKCLMEASVEERGFLTMFEDVSGLGSWHRRWCALSSNKLQYWKYPDDETRKDPMGYIDL 307

Query: 107 ---LSFRVAAVQPSDNISRKHTFKA-----------EHAGVRTYF--------FSAESPE 144
              ++ +V  +   D  +R HTF+            +    RTY          SA++ E
Sbjct: 308 KRCVTSKVGLI-SRDVCARPHTFELVTVRQPRRGEKDTLVSRTYNTMTTVRHQLSADTKE 484

Query: 145 EQEAWIQAMGEA 156
           E+  W   + +A
Sbjct: 485 ERIVWCNKVNQA 520
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|94397317|ref|XP_001004695.1| PREDICTED: dedicator of
cytokinesis 9 isoform 19 [Mus musculus]
         (2113 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

25905                                                                  61   5e-09
01477                                                                  34   0.73 
25083                                                                  32   2.5  
19246                                                                  32   3.6  
35264                                                                  31   4.3  
>25905
          Length = 482

 Score = 60.8 bits (146), Expect = 5e-09,   Method: Compositional matrix adjust.
 Identities = 40/135 (29%), Positives = 69/135 (51%), Gaps = 8/135 (5%)
 Frame = +3

Query: 750 VGFSWLPLLKDGRVLTSEQHIPVSAN-LPSGYLGYQELGMGRHYGPEVKWVEGGKPLLKI 808
           VG++W+PL  +GR++T E  +PVS   LP  Y  Y      +H    +KWV+  K +  +
Sbjct: 6   VGYTWVPLFHEGRLVTGEMSLPVSVERLPPHYSMYHPDAQLQH----MKWVDNHKGVFTV 173

Query: 809 STHLVSTVYTQDQHLHNF-----FQYCQKTESGAQASG--SELVKYLKSLHAMEGHVMIA 861
           +   +S+V+ QD+H+  F     F   QK       +G  +EL + +  +    G  ++ 
Sbjct: 174 NIKAISSVHAQDEHIDRFMHLWNFVQDQKLPPRMSENGFENELKRSIMDIVNARGESLVH 353

Query: 862 FLPTILNQLFRVLTR 876
           FL  IL++L  ++ R
Sbjct: 354 FLYLILDKLICLMVR 398
>01477
          Length = 945

 Score = 33.9 bits (76), Expect = 0.73,   Method: Composition-based stats.
 Identities = 29/93 (31%), Positives = 43/93 (46%), Gaps = 1/93 (1%)
 Frame = -2

Query: 242 RRFAFELKMQDKSSYLLAADSEAEMEEWVTVLNKILQL-NFEAAMQEKRNGDPHEDDEQS 300
           +RFA     +  S YLL+      + E V  L+   QL N  A + E   G   ++D+  
Sbjct: 485 KRFALSDSTETTSGYLLSIQLNCSLREVVAFLDDRSQLANAPALLPEHVLGPGGQNDDFC 306

Query: 301 KLEGSGSGLDSYLPELAKSTREAEIKLKSESRV 333
              G  S L + +P L+K TRE  I+L  E  +
Sbjct: 305 ACWGH-SHLHTAVPILSKFTREELIQLSLEKTI 210
>25083
          Length = 417

 Score = 32.0 bits (71), Expect = 2.5,   Method: Compositional matrix adjust.
 Identities = 28/88 (31%), Positives = 41/88 (46%), Gaps = 1/88 (1%)
 Frame = +2

Query: 241 VRRFAFELKMQDKSSYLLAADSEAEMEEWVTVLNKILQL-NFEAAMQEKRNGDPHEDDEQ 299
            +RFA     +  S YLL+      + E V  L+   QL N  A + E   G   ++D+ 
Sbjct: 62  AKRFALSDSTETTSGYLLSIQLNCSLREVVAFLDDRSQLANAPALLPEHVLGPGGQNDDF 241

Query: 300 SKLEGSGSGLDSYLPELAKSTREAEIKL 327
               G  S L + +P L+K TRE  I+L
Sbjct: 242 CACWGH-SHLHTAVPILSKFTREELIQL 322
>19246
          Length = 440

 Score = 31.6 bits (70), Expect = 3.6,   Method: Compositional matrix adjust.
 Identities = 21/74 (28%), Positives = 32/74 (43%), Gaps = 2/74 (2%)
 Frame = +2

Query: 227 IFLDSCMGVIQNN--RVRRFAFELKMQDKSSYLLAADSEAEMEEWVTVLNKILQLNFEAA 284
           I + SC+  I ++  R R+  F L    +S YLL A+ +  M  W+  +           
Sbjct: 170 ISIKSCLVDIAHDYSRKRKHVFRLTTYSESVYLLQAEDKGTMMSWIQAI----------- 316

Query: 285 MQEKRNGDPHEDDE 298
              K N +P  DDE
Sbjct: 317 ---KTNNNPDHDDE 349
>35264
          Length = 867

 Score = 31.2 bits (69), Expect = 4.3,   Method: Composition-based stats.
 Identities = 17/61 (27%), Positives = 27/61 (44%)
 Frame = -2

Query: 1896 CHNIRRFMFEMPFTQTGKRQGGVEEQCKRRTILTAIHCFPYVKKRIPVMYQHHTDLNPIE 1955
            CH + +     PF+     +GGV+        L  + C   V + +PV+ QHH    P+ 
Sbjct: 299  CHGVAQHQVAFPFSYITLXKGGVQ--------LNGLLC---VLQSLPVLLQHHVGGRPVP 153

Query: 1956 V 1956
            V
Sbjct: 152  V 150
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|112181173|ref|NP_031749.2| cyclic nucleotide gated
channel alpha 1 [Mus musculus]
         (684 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

19667                                                                  59   8e-09
24780                                                                  47   2e-05
08195                                                                  39   0.008
>19667
          Length = 442

 Score = 58.5 bits (140), Expect = 8e-09,   Method: Composition-based stats.
 Identities = 36/118 (30%), Positives = 58/118 (49%), Gaps = 2/118 (1%)
 Frame = +3

Query: 474 DCEAGL-LVELVLKLQPQVYSPGDYICKKGDIGREMYIIKEGKLAVVADDGITQFVVLSD 532
           DC  GL  V + L+     + PG+ +  KGD  R +Y +  G L V+ D+ +    +L  
Sbjct: 12  DCHPGLPFVPVALQTSRVFFGPGEVLIHKGDAIRNIYYVCSGSLEVLKDEQVV--AILGK 185

Query: 533 GSYFGEISILNIKGSKAGNRRTANIKSIGYSDLFCLSKDDLMEALTEYPD-AKTMLEE 589
           G  FG     +IK     +    +++S+ Y +L C++   L E L  YPD ++  LEE
Sbjct: 186 GDLFGS----DIKFEDPVSISGGDVRSLAYCELLCINTQGLAECLQPYPDFSEKFLEE 347
>24780
          Length = 572

 Score = 47.4 bits (111), Expect = 2e-05,   Method: Composition-based stats.
 Identities = 19/34 (55%), Positives = 28/34 (82%)
 Frame = +3

Query: 551 NRRTANIKSIGYSDLFCLSKDDLMEALTEYPDAK 584
           NRRTA+++S GY+++F LSK D  EA+ EYP+A+
Sbjct: 3   NRRTADVRSSGYTNVFTLSKHDFEEAMNEYPEAQ 104
>08195
          Length = 2165

 Score = 38.5 bits (88), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 22/80 (27%), Positives = 36/80 (45%), Gaps = 8/80 (10%)
 Frame = -3

Query: 487  LQPQVYSPGDYICKKGDIGREMYIIKEGKLAVVADD--------GITQFVVLSDGSYFGE 538
            LQ + Y  G  I K+GD    MY ++ G++ +   +        G T   VL  G YFGE
Sbjct: 1206 LQTRTYEDGVQIIKQGDAADVMYFVESGQVRIAMTNKESTDPSAGETDVTVLEKGGYFGE 1027

Query: 539  ISILNIKGSKAGNRRTANIK 558
            ++++  +   A       +K
Sbjct: 1026 LALITHQPRAASAYAQGTVK 967

 Score = 35.4 bits (80), Expect = 0.070,   Method: Compositional matrix adjust.
 Identities = 21/81 (25%), Positives = 42/81 (51%), Gaps = 2/81 (2%)
 Frame = -3

Query: 464  DTLKKVRIFADCEAGLLVELVLKLQPQVYSPGDYICKKGDIGREMYIIKEGKLAVVAD-D 522
            D +K + +F   +   + E++  +  +   PG++I  +GD G   Y+I  G   +  D +
Sbjct: 1641 DVVKNILLFRSLDPEQMQEVLDAMFEKSVQPGEHIIDQGDDGDNFYVIDSGTYDIYVDVE 1462

Query: 523  GITQFVVLSDGS-YFGEISIL 542
            G  + V   D S +FGE++++
Sbjct: 1461 GQAKLVGNYDNSGFFGELALM 1399
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|27754146|ref|NP_079627.2|
coiled-coil-helix-coiled-coil-helix domain containing 6 [Mus musculus]
         (273 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

07264                                                                  57   8e-09
08765                                                                  56   1e-08
>07264
          Length = 1581

 Score = 57.0 bits (136), Expect = 8e-09,   Method: Compositional matrix adjust.
 Identities = 27/82 (32%), Positives = 46/82 (56%)
 Frame = +1

Query: 192 FYKEQQGRIQEKNAELYKLSSQQFHEAASKAESTIKPRRVEPVCSGLQAQILRCYRDHLH 251
           FY ++  +++E+N EL K++++QF +A  + E          VC  LQ+++  CY D+  
Sbjct: 229 FYTQRLKQLEERNTELQKITNEQFVKAVQEVEQKFLKHTSTAVCQDLQSKVYECYLDNPK 408

Query: 252 EVLLCSDLVKAYQHCVSTARKG 273
             L CS  V+A+  CV  AR+ 
Sbjct: 409 HTLNCSAQVRAFSTCVERARQN 474
>08765
          Length = 475

 Score = 56.2 bits (134), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 27/82 (32%), Positives = 46/82 (56%)
 Frame = +2

Query: 192 FYKEQQGRIQEKNAELYKLSSQQFHEAASKAESTIKPRRVEPVCSGLQAQILRCYRDHLH 251
           FY ++  +++E+N EL K++++QF +A  + E          VC  LQ+++  CY D+  
Sbjct: 191 FYTQRLKQLEERNTELQKITNEQFVKAVQEVEQKFLKHTSTAVCQDLQSKVYECYLDNPK 370

Query: 252 EVLLCSDLVKAYQHCVSTARKG 273
             L CS  V+A+  CV  AR+ 
Sbjct: 371 HTLNCSAEVRAFSTCVERARQN 436
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6679249|ref|NP_032829.1| phosphodiesterase 8A [Mus
musculus]
         (823 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

19664                                                                  59   8e-09
05814                                                                  33   0.43 
23608                                                                  32   0.98 
21560                                                                  31   2.2  
>19664
          Length = 420

 Score = 58.9 bits (141), Expect = 8e-09,   Method: Composition-based stats.
 Identities = 25/58 (43%), Positives = 37/58 (63%), Gaps = 5/58 (8%)
 Frame = +1

Query: 770 KSQISFIDYFITDMFDAWDAFVDLPNLMQHLDDNFRYWKGLDEKKLRSL-----RPPP 822
           KSQI FI+Y I DM +AWD+F+D+P L+  +  N+  WK  DE+ + +L     + PP
Sbjct: 1   KSQIGFIEYIIQDMMEAWDSFIDMPQLITCMKINYAQWKKYDEQGVNTLADIMAKQPP 174
>05814
          Length = 1242

 Score = 33.1 bits (74), Expect = 0.43,   Method: Compositional matrix adjust.
 Identities = 40/143 (27%), Positives = 61/143 (42%), Gaps = 5/143 (3%)
 Frame = +3

Query: 681 KPLTAQESEEPDRSLEDIKAMLKTPESR---ALIKRMMIKCADVSNPCRPLEHCIEWAAR 737
           KPL  Q S   D+ ++  K +++   S+   ALI+RM      V+   +P+ H I     
Sbjct: 39  KPLGXQSSS--DKGVDYDKLIVRFGSSKIDDALIQRM----EKVTG--KPVHHFIRRGI- 191

Query: 738 ISEEYFSQTDEEKQLDLPVVMPVFDRNTCSIPKSQISFIDYFITDMFDAW--DAFVDLPN 795
               +FS  D    LDL      F   T   P S    + + +  +   W  D F D+P 
Sbjct: 192 ----FFSHRDMHALLDLYEKKQPFYLYTGRGPSSDAMHLGHLVPFIMTKWLQDVF-DVPL 356

Query: 796 LMQHLDDNFRYWKGLDEKKLRSL 818
           ++Q  DD    WK L E +  +L
Sbjct: 357 VIQLTDDEKYLWKDLSEDEAHAL 425
>23608
          Length = 2321

 Score = 32.0 bits (71), Expect = 0.98,   Method: Compositional matrix adjust.
 Identities = 15/30 (50%), Positives = 17/30 (56%)
 Frame = +3

Query: 319 IRVCNGNNKVETTTECVQTDSQTDNQAGKH 348
           IR+ NG N+V T     QTD QTD Q   H
Sbjct: 795 IRINNGENRVHTFVHETQTDRQTDRQTHTH 884
>21560
          Length = 418

 Score = 30.8 bits (68), Expect = 2.2,   Method: Composition-based stats.
 Identities = 13/30 (43%), Positives = 16/30 (53%)
 Frame = -2

Query: 702 LKTPESRALIKRMMIKCADVSNPCRPLEHC 731
           L  P   AL+ +M     D+ N C PLEHC
Sbjct: 408 LTLPSFPALVTQMKTGIMDIKNFCTPLEHC 319
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|7110699|ref|NP_032964.1| peripherin 2 [Mus musculus]
         (346 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

11991                                                                  57   8e-09
25023                                                                  53   2e-07
16993                                                                  31   0.66 
21164                                                                  27   8.3  
21291                                                                  27   8.5  
>11991
          Length = 881

 Score = 57.4 bits (137), Expect = 8e-09,   Method: Compositional matrix adjust.
 Identities = 60/265 (22%), Positives = 107/265 (40%), Gaps = 9/265 (3%)
 Frame = -2

Query: 15  KLAQGLWLM-NWLSVLAGIVLFSLGLFLKIELRKRSEVMNNSESHFVPNSLIGVGVLSCV 73
           K+ +GL+L  N+L ++ GI + ++G +L +E      +M   +   V   +I  G++  V
Sbjct: 877 KIIRGLFLFCNFLGIVMGIAMVAIGAYLYVEKNDFLNLMPKYDDINVTAVMIAAGIVVLV 698

Query: 74  FNSLAGKICYDALDPAKYAKWKPWLKPYLAVCIFFNVILFL------VALCCFLLRGSLE 127
              +    C              W++    + +FF  I  +      V +  F+ R  ++
Sbjct: 697 IACIG--FC------------GAWMESQCMLIMFFTAIFIIFAMEIAVGIIGFIYRDDID 560

Query: 128 STLAYGLKNGMKYYRDTDTPGRCFMKKTIDMLQIEFKCCGNNGFRDWFEIQWISNRYLDF 187
           S L   LK G+K       P R     T D++Q E+ CCG + ++DWF +          
Sbjct: 559 SELNTQLKEGLK------EPKR---HSTWDVIQKEYDCCGVDTYQDWFTV---------- 437

Query: 188 SSKEVKDRIKSNVDGRYLVDGVPFSCCNPSS--PRPCIQYQLTNNSAHYSYDHQTEELNL 245
                            LV+ VP SCC+ ++    P    QL ++   YS   +  E + 
Sbjct: 436 -----------------LVNRVPDSCCSHTNCGTNP----QLASDXGCYSKVKEEIEDHF 320

Query: 246 WLRGCRAALLNYYSSLMNSMGVVTL 270
           ++ G     L     L+  M +V +
Sbjct: 319 YVLGAAGIALGVLQILLLVMTMVLI 245
>25023
          Length = 893

 Score = 53.1 bits (126), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 40/164 (24%), Positives = 72/164 (43%)
 Frame = -3

Query: 20  LWLMNWLSVLAGIVLFSLGLFLKIELRKRSEVMNNSESHFVPNSLIGVGVLSCVFNSLAG 79
           + + N++  + GIV+ ++G++ K++L K  E+ +  +    P  LIGVG +  +  SL  
Sbjct: 741 MMVFNFIFWVTGIVILAIGIWTKVDLYKYLELSSIYQPE-APYVLIGVGAVIVLVGSLG- 568

Query: 80  KICYDALDPAKYAKWKPWLKPYLAVCIFFNVILFLVALCCFLLRGSLESTLAYGLKNGMK 139
             C   +    +      L  Y  V     ++     +   + +G LE     GL + + 
Sbjct: 567 --CCCTIKGHAF-----LLYMYCGVLFLVFIMELSAGITLLVYKGKLEKGFKEGLGSAID 409

Query: 140 YYRDTDTPGRCFMKKTIDMLQIEFKCCGNNGFRDWFEIQWISNR 183
            Y   D  G   +    D LQ +  CCG N + DWF  +W + +
Sbjct: 408 RY---DQKGEEEITAAFDELQQKLSCCGINSYSDWFSSEWAAKQ 286
>16993
          Length = 2290

 Score = 31.2 bits (69), Expect = 0.66,   Method: Compositional matrix adjust.
 Identities = 11/27 (40%), Positives = 16/27 (59%)
 Frame = -1

Query: 151  FMKKTIDMLQIEFKCCGNNGFRDWFEI 177
            + +K  D LQ EF CCG + + DW  +
Sbjct: 1822 WCQKAWDKLQTEFSCCGAHNYTDWQNV 1742
>21164
          Length = 609

 Score = 27.3 bits (59), Expect = 8.3,   Method: Compositional matrix adjust.
 Identities = 20/67 (29%), Positives = 31/67 (46%), Gaps = 4/67 (5%)
 Frame = +3

Query: 36  SLGLFLKIELRKRSEVMNNSESHFVPNSLI----GVGVLSCVFNSLAGKICYDALDPAKY 91
           S+  F+K E+  R   M+    H  P  L+    G G ++C F+SL+  +    L+  K 
Sbjct: 246 SIIYFVKEEVSVR*GSMDQFSIHEFPK*LVRPLAGKGTVTCFFDSLSVYLLIMNLNEIKL 425

Query: 92  AKWKPWL 98
              K WL
Sbjct: 426 LTMKSWL 446
>21291
          Length = 368

 Score = 27.3 bits (59), Expect = 8.5,   Method: Compositional matrix adjust.
 Identities = 13/38 (34%), Positives = 19/38 (50%)
 Frame = +2

Query: 86  LDPAKYAKWKPWLKPYLAVCIFFNVILFLVALCCFLLR 123
           +DP  Y  W+P  + YL +    NV  F +A+ C   R
Sbjct: 2   IDPTTYGTWEPTKQHYLPLQCCSNVCSFKIAIFCLSSR 115
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|27229192|ref|NP_083069.1| acyl-Coenzyme A binding
domain containing 5 isoform c [Mus musculus]
         (473 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

13742                                                                  58   9e-09
02727                                                                  28   8.2  
>13742
          Length = 982

 Score = 57.8 bits (138), Expect = 9e-09,   Method: Compositional matrix adjust.
 Identities = 31/85 (36%), Positives = 45/85 (52%), Gaps = 1/85 (1%)
 Frame = -3

Query: 387 LNEQIALVLIRLQEDMQNVLQRLHKLETLTASQAKLSLQTSNQPSSQRPAWWPFE-MSPG 445
           + E+I L LIR+Q+DM ++  RL  LE     Q     +      S++  WWPF  +S  
Sbjct: 968 VEEEILLALIRMQQDMTDISHRLAALEHCVKQQ-----REEQTKKSRKSMWWPFNGVSKT 804

Query: 446 ALAFAIIWPFIAQWLAHLYYQRRRR 470
                ++WPF+A  L +L  QRRRR
Sbjct: 803 TFFLLVVWPFLAPVLINLICQRRRR 729
>02727
          Length = 1905

 Score = 28.1 bits (61), Expect = 8.2,   Method: Compositional matrix adjust.
 Identities = 24/69 (34%), Positives = 29/69 (42%)
 Frame = -3

Query: 374 GERWGSDRGSRGSLNEQIALVLIRLQEDMQNVLQRLHKLETLTASQAKLSLQTSNQPSSQ 433
           G   G  RG  G    Q  L L+RL+ D +        L T T    KL L      S+ 
Sbjct: 898 GRNAGKVRGIVG----QRGLGLVRLEHDSK-------PLSTTTHDGQKLCL------STY 770

Query: 434 RPAWWPFEM 442
           RP WWP E+
Sbjct: 769 RPQWWPDEL 743
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|58037355|ref|NP_083089.1| vitrin [Mus musculus]
         (650 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

38717                                                                  58   9e-09
02426                                                                  55   7e-08
28675                                                                  30   2.1  
>38717
          Length = 661

 Score = 58.2 bits (139), Expect = 9e-09,   Method: Compositional matrix adjust.
 Identities = 25/90 (27%), Positives = 55/90 (61%)
 Frame = -1

Query: 466 ADIGFVIDGSSSMGTSNFRTVLQFVANLSKEFEISDTDTRVGAVQYTYEQRLEFGFDKYN 525
           AD+ F++D S S+G  N + +L F+ N+  E++I     RVG ++++ +  +EF  ++Y+
Sbjct: 490 ADVVFLVDDSGSIGDDNNKLLLGFLENVLNEWDIGQDKIRVGIMRFSDKINIEFMLNRYD 311

Query: 526 SKADILSAIRRVGYWSGGTSTGAAIQYALE 555
            + +++ A+++  Y  G T T +A+   ++
Sbjct: 310 DRDEMVDAVKKFKYEEGFTYTHSALDKMMK 221

 Score = 53.1 bits (126), Expect = 4e-07,   Method: Compositional matrix adjust.
 Identities = 37/148 (25%), Positives = 65/148 (43%), Gaps = 2/148 (1%)
 Frame = -1

Query: 225 EEVDGWKPGPVLLDSGFVPKEELSTQSSEPVPQGD--PNCKIDLSFLIDGSTSIGKRRFR 282
           EE +      ++ DS       + TQ  + +P  D  P  K D+ FL+D S SIG    +
Sbjct: 613 EEAEDQAMQKLMADSASTILSMVDTQVCQFMPDTDCGPGLKADVVFLVDDSGSIGDDNNK 434

Query: 283 IQKQFLADVVQALDIGPAGPLVGVVQYGDNPATQFNLKTHMNSQDLKTAIEKITQRGGLS 342
           +   FL +V+   DIG     VG++++ D    +F L  + +  ++  A++K     G +
Sbjct: 433 LLLGFLENVLNEWDIGQDKIRVGIMRFSDKINIEFMLNRYDDRDEMVDAVKKFKYEEGFT 254

Query: 343 NVGRAISFVTKTFFSKANGNRGGAPNVA 370
               A+  + K    +  G     P +A
Sbjct: 253 YTHSALDKMMKLCLLRPMGTDRQYPTLA 170

 Score = 31.6 bits (70), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 17/51 (33%), Positives = 27/51 (52%), Gaps = 2/51 (3%)
 Frame = -3

Query: 353 KTFFSKANGNRGGAPNVAVVMVDGWPT--DKVEEVSRVARESGINVFFITV 401
           +  F+ ANG+R   PN  +V+ DG  T   K    ++ A+E GI +  + V
Sbjct: 224 EVMFTAANGDRPTVPNFGIVITDGKSTLEQKTLNEAQKAKEQGITMLAVGV 72
>02426
          Length = 1659

 Score = 55.5 bits (132), Expect = 7e-08,   Method: Compositional matrix adjust.
 Identities = 35/111 (31%), Positives = 56/111 (50%), Gaps = 5/111 (4%)
 Frame = +3

Query: 542 GGTSTGAAIQYALEQLFKKSKPNK---RKVMIIITDGRSYDDVRIPAMAAYQK--GVITY 596
           GGT+T A +  A   L+  S+  +   +KV +++TDGRS +     A A   K  G   +
Sbjct: 150 GGTNTAAGLNTARSTLYSSSRGARSDVKKVAVLVTDGRSNNFAYTKAAATRLKTEGTTVF 329

Query: 597 AIGIAWAAQDELEVMATHPAKDHSFFVDDFDNLYKIAPRIIQNICTEFNSQ 647
           A+G+     DEL+ +A+ P   H   +  FD++  I   I ++ C E N Q
Sbjct: 330 AVGVGNYRLDELQAVASEPKCSHVLTLTSFDHIKSILTEIQKSTC-EANYQ 479
>28675
          Length = 596

 Score = 30.4 bits (67), Expect = 2.1,   Method: Composition-based stats.
 Identities = 22/81 (27%), Positives = 34/81 (41%), Gaps = 14/81 (17%)
 Frame = +1

Query: 374 VDGWPT---------DKVEEVSRVARESGINVFFITVEGAAE-----RDIQHVVEPGFAS 419
           VDGWP          D VEE+S + +  G++      EGA+      RD  H+ + G   
Sbjct: 160 VDGWPEWKSVRALSGDPVEEMSTLRQAEGLHTGHSACEGASVCGFS*RDSGHIPQRGQRV 339

Query: 420 KAVCRTNGFYSFNVQSWLSLH 440
              C T   +++  Q    +H
Sbjct: 340 SGTCSTTISWTWGAQVLHQVH 402
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|15011853|ref|NP_058081.2| syntaxin 1A (brain) [Mus
musculus]
         (288 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

08305                                                                  57   1e-08
15043                                                                  30   1.6  
>08305
          Length = 1314

 Score = 56.6 bits (135), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 57/244 (23%), Positives = 113/244 (46%), Gaps = 10/244 (4%)
 Frame = -3

Query: 30   MDEFFEQVEEIRGFIDKIAENVEEVKRKHSAILASPNPDEKTKEELEELMSDIKKTANKV 89
            + +   +  +I G +      V E+K+    ++ SP  D+      E ++ ++ +   ++
Sbjct: 1120 LSDLLSKASQIDGDLSSYKSRVTELKKLQLDLVYSPFADKDAVSRYEGMIQELTRHXVRI 941

Query: 90   RSKLKSIEQSIEQEEGLNRSSAD---LRIRKTQHSTLSRKFVEVMSEYNATQSDYRERCK 146
            R+ ++ +E   + ++ +++   D    R+ K Q + L+ +     +E+   QSDY ++ K
Sbjct: 940  RNDIRQLEG--QADKYIDKKPDDEAFKRVSKQQLNGLTTQLAITTNEFFKCQSDYADKMK 767

Query: 147  GRIQRQLEITGRTTTSEELEDMLESGNPAIFASGIIMDSSISKQALSEIETRH------- 199
             R++ QL+  G + T E    M  SG      S     SS+  + L     +H       
Sbjct: 766  ERLKGQLQARGESVTDER*--MKFSGRTRTMCSH--RTSSLKCRMLQ----KH*GSWKSA 611

Query: 200  SEIIKLETSIRELHDMFMDMAMLVESQGEMIDRIEYNVEHAVDYVERAVSDTKKAVKYQS 259
            +    L  S+ +++ +F ++ ++V  QGE +D IE N+E    +VE       +AVK Q 
Sbjct: 610  TMTFLLLKSVTDVNMLFKELNLMVSQQGEKLDSIEQNIEQVEVHVESGKEQLTEAVKSQX 431

Query: 260  KARR 263
            KA R
Sbjct: 430  KAXR 419
>15043
          Length = 973

 Score = 29.6 bits (65), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 14/44 (31%), Positives = 26/44 (59%)
 Frame = +2

Query: 45  DKIAENVEEVKRKHSAILASPNPDEKTKEELEELMSDIKKTANK 88
           D IAE  +++ R    I A+P P+     ++E+L+SD++   N+
Sbjct: 467 DIIAEMRQDISRLRDKIAAAPEPNRDDVAKMEDLVSDLQLAKNR 598
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|172072590|ref|NP_036116.3| neurochondrin [Mus
musculus]
         (729 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

09295                                                                  43   1e-08
15581                                                                  29   5.9  
>09295
          Length = 1434

 Score = 42.7 bits (99), Expect(2) = 1e-08,   Method: Compositional matrix adjust.
 Identities = 78/355 (21%), Positives = 132/355 (37%), Gaps = 22/355 (6%)
 Frame = -1

Query: 91   TKEAPDGCPDHVLRALGVALLACFCSDPELASHPQVLNKIPILSTFLTARGDPDDAARRS 150
             KE P G    V R++ V +L+    D E+A+  ++   +P L + L      +D   R+
Sbjct: 1221 NKEDPGG-XGQVFRSVAVNILSALVVDCEMAADRRLGKVLPHLKSILETSFAQEDKEDRT 1045

Query: 151  MIDDT----YQCLTAVAGTPRGPRHLIAGGTVSALCQAYLGHGYGFDQXXXXXXXXXXXX 206
            ++ DT    +  L+  AGT  G   L+  G    L Q    H    ++            
Sbjct: 1044 LVXDTVRDTFTLLSRXAGTVVGGHMLLDCGYPQVLVQVL--HSKPDEEIFVMTQTLLILL 871

Query: 207  ETQ----CWKEAEPDLLAVLRGLSEDFQRAEDASKFEXXXXXXXXXXXXXXXXECHRD-- 260
            ++Q     W   E      L  LS+     +D    +                   R   
Sbjct: 870  QSQQGDAVWAGXEDVFDCYLSVLSQRLSACQDKHIIDMCELTTCILSLAPKGESNTRTSA 691

Query: 261  ---LQAGLARILGSKLSSWQRNPALKLAARLAHACGSD-WIPVGSSGSKFLALLVNLACV 316
               L   L+ ++ S+L   QR   L L  ++    G D  +P          L+++L  +
Sbjct: 690  VQPLVDKLSSLIRSRLGVSQRQAVLXLLNQVTVTLGVDCLLPPAVPDYTXWLLVLHLTTI 511

Query: 317  EVRLALEETGTEVKEDVVTACYALMELGIQE-----CTRCEQSLLKEPQKV--QLVSIMK 369
            EVRLALE + T  + D   A   L    ++      C       L  P +   Q    + 
Sbjct: 510  EVRLALENS-TPHQLDXYAAKLCLHFNALETMLNFLCRHDHDHALPLPAEAFCQAHDALL 334

Query: 370  EAIGAVIHYLLQVGPEKQKEPFV-FASVRILGAWLAEETSSLRKEVCQLLPFLVR 423
             A   + ++L Q+     +   V  ASVR++ A   +    +++ V  LLP L++
Sbjct: 333  GAATGLFYFLQQLDINNLRADMVTVASVRMMAAITCQAFDEVKENVVALLPVLLK 169

 Score = 35.0 bits (79), Expect(2) = 1e-08,   Method: Compositional matrix adjust.
 Identities = 20/60 (33%), Positives = 30/60 (50%), Gaps = 4/60 (6%)
 Frame = -2

Query: 38   RYLGA----LREAKNDSEQFXXXXXXXXXXXXGDIDAKTRRRIFDAVGFTFPNRLLTTKE 93
            R+L A    L +AK D+E+F             +  A  ++ + DAVG +F  RLL TK+
Sbjct: 1391 RHLNACLRGLEQAKTDTEKFASLLMVTKSIKAEECSAADKKNLLDAVGLSFFIRLLRTKK 1212
>15581
          Length = 524

 Score = 29.3 bits (64), Expect = 5.9,   Method: Compositional matrix adjust.
 Identities = 15/52 (28%), Positives = 24/52 (46%)
 Frame = +2

Query: 673 SVSPNSVKPEMVAAYQGVLVELARANRLCREAMRLQAGEETASHYRMAALEQ 724
           S+SP+   P  +  ++    +L      CRE  R    E+ A H+   AL+Q
Sbjct: 302 SISPSPF*PFHLLNWKYAQAQLGEQEGFCRERTRTLGHEQNALHFATKALKQ 457
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|188219551|ref|NP_034252.2| eukaryotic translation
initiation factor 2B, subunit 4 delta isoform 2 [Mus musculus]
         (524 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

13316                                                                  57   1e-08
>13316
          Length = 1362

 Score = 57.4 bits (137), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 39/119 (32%), Positives = 63/119 (52%), Gaps = 3/119 (2%)
 Frame = +2

Query: 398 EVSKVLLGAHALLANGSVMSRVGTAQLALVARAHNVPVLVCC--ETYKFCERVQTDAFVS 455
           ++S V++GA  ++ANG   ++VGT QLA+VA+ H VP  V C   TY   +    D  + 
Sbjct: 818 KISAVVVGADRVVANGDTANKVGTYQLAIVAKHHKVPFYVACPLTTYDGSKASGDDIII- 994

Query: 456 NELDDPDDLQCKRGDQVALANWQSHPSLRLLNLVYDVTPPELV-DLVITELGMIPCSSV 513
            E     ++   +G ++A         ++  N  +DVTP EL+   +ITE G+ P S +
Sbjct: 995 -EERPAVEMTSIKGVRLAAEG------IKCWNPAFDVTPAELITGGIITEFGVFPPSKL 1150
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31560462|ref|NP_058077.2| syntaxin 7 [Mus musculus]
         (261 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

08305                                                                  57   1e-08
30761                                                                  54   6e-08
20723                                                                  28   4.1  
>08305
          Length = 1314

 Score = 56.6 bits (135), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 24/59 (40%), Positives = 39/59 (66%)
 Frame = -3

Query: 178 LEADIMDINEIFKDLGMMIHEQGDMIDSIEANVESAEVHVQQANQQLSRAADYQRKSRK 236
           L   + D+N +FK+L +M+ +QG+ +DSIE N+E  EVHV+   +QL+ A   Q K+ +
Sbjct: 595 LLKSVTDVNMLFKELNLMVSQQGEKLDSIEQNIEQVEVHVESGKEQLTEAVKSQXKAXR 419
>30761
          Length = 367

 Score = 53.9 bits (128), Expect = 6e-08,   Method: Compositional matrix adjust.
 Identities = 23/53 (43%), Positives = 36/53 (67%)
 Frame = +1

Query: 182 IMDINEIFKDLGMMIHEQGDMIDSIEANVESAEVHVQQANQQLSRAADYQRKS 234
           I+ +NEI+K+LG M++EQG  +DSIE+ VE   + V Q    L +A+ Y+ K+
Sbjct: 190 IVGVNEIYKNLGAMVYEQGLTVDSIESQVEQTSIFVSQGTDNLRKASSYRVKN 348
>20723
          Length = 809

 Score = 28.1 bits (61), Expect = 4.1,   Method: Compositional matrix adjust.
 Identities = 18/61 (29%), Positives = 33/61 (54%)
 Frame = +1

Query: 177 QLEADIMDINEIFKDLGMMIHEQGDMIDSIEANVESAEVHVQQANQQLSRAADYQRKSRK 236
           Q+ A I+ INE+  DLG  +     ++D  + NV+    ++ +  Q+ S+A   ++K  K
Sbjct: 406 QVXAYILTINEVIFDLGQSLCPFSGLLDLPDHNVKH---NIDKYIQKTSKAYYLKKKDFK 576

Query: 237 T 237
           T
Sbjct: 577 T 579
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6754920|ref|NP_035084.1| neural cell adhesion
molecule 2 isoform b [Mus musculus]
         (727 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

08294                                                                  58   1e-08
20110                                                                  52   1e-08
29990                                                                  54   2e-08
13135                                                                  55   1e-07
11855                                                                  50   4e-06
37675                                                                  50   4e-06
27666                                                                  48   1e-05
25455                                                                  45   8e-05
06028                                                                  45   1e-04
38127                                                                  40   0.003
36498                                                                  30   0.005
25766                                                                  39   0.007
11732                                                                  38   0.015
19356                                                                  37   0.020
18345                                                                  37   0.023
17530                                                                  36   0.045
32888                                                                  35   0.073
29932                                                                  35   0.12 
19544                                                                  34   0.20 
36700                                                                  34   0.20 
10921                                                                  34   0.21 
12764                                                                  33   0.35 
35419                                                                  33   0.53 
34811                                                                  32   0.80 
20244                                                                  26   0.81 
27008                                                                  30   3.8  
22019                                                                  30   4.3  
39864                                                                  29   6.4  
>08294
          Length = 1849

 Score = 58.2 bits (139), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 37/105 (35%), Positives = 49/105 (46%)
 Frame = +2

Query: 184 YRCEGRVEARGEIDFRDIIVIVNVPPAIMMPQKSFNATAERGEEMTLTCKASGSPDPTIS 243
           Y C      +G I+    I IV  P AI +  KS N T   G    L C A GSP P I+
Sbjct: 5   YTCVATHPRQGVINATIHISIVEWP-AITV--KSNNITVFEGHSAILHCVAKGSPSPDIA 175

Query: 244 WFRNGKLIEENEKYILKGSNTELTVRNIINKDGGSYVCKATNKAG 288
           W+R+ + I  N +      N  + +R +  +D G Y C A N AG
Sbjct: 176 WYRDSQPILPNARRYTLFKNGTMKIRQVFMEDNGMYACVANNTAG 310

 Score = 43.1 bits (100), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 31/111 (27%), Positives = 49/111 (44%), Gaps = 2/111 (1%)
 Frame = +2

Query: 279 YVCKATN-KAGEDQKQAFLQVFVQPHILQLKNETTSENGHVTLV-CEAEGEPVPEITWKR 336
           Y C AT+ + G       + +   P I    N  T   GH  ++ C A+G P P+I W R
Sbjct: 5   YTCVATHPRQGVINATIHISIVEWPAITVKSNNITVFEGHSAILHCVAKGSPSPDIAWYR 184

Query: 337 AIDGVMFSEGDKSPDGRIEVKGQHGRSSLHIRDVKLSDSGRYDCEAASRIG 387
               ++       P+ R     ++G  ++ IR V + D+G Y C A +  G
Sbjct: 185 DSQPIL-------PNARRYTLFKNG--TMKIRQVFMEDNGMYACVANNTAG 310

 Score = 29.6 bits (65), Expect = 4.0,   Method: Compositional matrix adjust.
 Identities = 20/96 (20%), Positives = 35/96 (36%)
 Frame = +2

Query: 91  YRCQATDAKGQTQEATVVLEIYQKLTFREVVSPQEFKQGEDAEVVCRVSSSPAPAVSWLY 150
           Y C AT  +     AT+ + I +        +     +G  A + C    SP+P ++W Y
Sbjct: 5   YTCVATHPRQGVINATIHISIVEWPAITVKSNNITVFEGHSAILHCVAKGSPSPDIAW-Y 181

Query: 151 HNEEVTTIPDNRFAVLAXXXXXXXXXXKSDEGIYRC 186
            + +       R+ +              D G+Y C
Sbjct: 182 RDSQPILPNARRYTLFKNGTMKIRQVFMEDNGMYAC 289
>20110
          Length = 820

 Score = 51.6 bits (122), Expect(2) = 1e-08,   Method: Compositional matrix adjust.
 Identities = 35/111 (31%), Positives = 54/111 (48%), Gaps = 3/111 (2%)
 Frame = -1

Query: 178 KSDEGIYRCEGRVEARGEIDFRDII--VIVNVPPAIMMPQKSFNATAERGEEMTLTCKAS 235
           ++D GIY C  R+ A    ++   I  + V VPP+I     +     E+G+  TL C AS
Sbjct: 652 ETDAGIYTCTVRITAVSYEEWPTKIGNLTVQVPPSIKPGDTTAVLQIEQGQNSTLVCAAS 473

Query: 236 GSPDPTISWFR-NGKLIEENEKYILKGSNTELTVRNIINKDGGSYVCKATN 285
           G P P I+W R +G  +      + +  +  L + N+  +D G Y C A N
Sbjct: 472 GIPAPNITWTRSDGGFLPIG---VAQFRSATLPMNNVTVRDMGVYRCVADN 329

 Score = 26.2 bits (56), Expect(2) = 1e-08,   Method: Compositional matrix adjust.
 Identities = 10/26 (38%), Positives = 14/26 (53%)
 Frame = -3

Query: 318 VTLVCEAEGEPVPEITWKRAIDGVMF 343
             L C  +G P P +TW+ AI+   F
Sbjct: 221 ANLECIVKGHPEPTVTWEMAINNGRF 144

 Score = 45.8 bits (107), Expect = 6e-05,   Method: Compositional matrix adjust.
 Identities = 44/130 (33%), Positives = 59/130 (45%), Gaps = 9/130 (6%)
 Frame = -1

Query: 266 LTVRNIINKDGGSYVC--KATNKAGED--QKQAFLQVFVQPHILQLKNETTS----ENG- 316
           L VR ++  D G Y C  + T  + E+   K   L V V P I     +TT+    E G 
Sbjct: 673 LVVRRLVETDAGIYTCTVRITAVSYEEWPTKIGNLTVQVPPSIK--PGDTTAVLQIEQGQ 500

Query: 317 HVTLVCEAEGEPVPEITWKRAIDGVMFSEGDKSPDGRIEVKGQHGRSSLHIRDVKLSDSG 376
           + TLVC A G P P ITW R       S+G   P G      Q   ++L + +V + D G
Sbjct: 499 NSTLVCAASGIPAPNITWTR-------SDGGFLPIG----VAQFRSATLPMNNVTVRDMG 353

Query: 377 RYDCEAASRI 386
            Y C A + I
Sbjct: 352 VYRCVADNNI 323

 Score = 34.7 bits (78), Expect = 0.14,   Method: Compositional matrix adjust.
 Identities = 23/105 (21%), Positives = 42/105 (40%), Gaps = 5/105 (4%)
 Frame = -1

Query: 87  DAGIYRCQATDAKGQTQE-----ATVVLEIYQKLTFREVVSPQEFKQGEDAEVVCRVSSS 141
           DAGIY C         +E       + +++   +   +  +  + +QG+++ +VC  S  
Sbjct: 646 DAGIYTCTVRITAVSYEEWPTKIGNLTVQVPPSIKPGDTTAVLQIEQGQNSTLVCAASGI 467

Query: 142 PAPAVSWLYHNEEVTTIPDNRFAVLAXXXXXXXXXXKSDEGIYRC 186
           PAP ++W   +     I   +F                D G+YRC
Sbjct: 466 PAPNITWTRSDGGFLPIGVAQF---RSATLPMNNVTVRDMGVYRC 341

 Score = 33.1 bits (74), Expect = 0.41,   Method: Compositional matrix adjust.
 Identities = 19/71 (26%), Positives = 33/71 (46%), Gaps = 16/71 (22%)
 Frame = -3

Query: 230 LTCKASGSPDPTISW---FRNGKL-IEENEKYILKGSNTE------------LTVRNIIN 273
           L C   G P+PT++W     NG+  I +++ +++    T+            L V+N++ 
Sbjct: 215 LECIVKGHPEPTVTWEMAINNGRFPITDHDDFVINKLTTDNQNLKAGEQWYTLKVKNVLG 36

Query: 274 KDGGSYVCKAT 284
            D   Y C AT
Sbjct: 35  NDFTDYYCIAT 3
>29990
          Length = 434

 Score = 54.3 bits (129), Expect(2) = 2e-08,   Method: Compositional matrix adjust.
 Identities = 32/107 (29%), Positives = 47/107 (43%), Gaps = 1/107 (0%)
 Frame = +3

Query: 142 PAPAVSWLYHNEEVTTIPDNRFAVLAXXXXXXXXXXKSDEGIYRCEGRVEARGEIDFRDI 201
           P P + W+++N  V    D+RF++L             D G+Y C  R  A GE     +
Sbjct: 12  PVPEIVWMHNNNRVEISGDSRFSLLHDGTLMIEDAQDDDRGVYECIARNVA-GETHSNQV 188

Query: 202 -IVIVNVPPAIMMPQKSFNATAERGEEMTLTCKASGSPDPTISWFRN 247
            +       A    Q+  +     G+ + L C+ASG P PT SW RN
Sbjct: 189 ELRYFGERVAPXFTQRPQDIVTVEGQTVQLVCQASGHPRPTFSWTRN 329

 Score = 22.7 bits (47), Expect(2) = 2e-08,   Method: Composition-based stats.
 Identities = 9/18 (50%), Positives = 11/18 (61%)
 Frame = +2

Query: 266 LTVRNIINKDGGSYVCKA 283
           LT+RN+   D G Y C A
Sbjct: 380 LTIRNVQESDRGDYQCYA 433

 Score = 50.4 bits (119), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 36/111 (32%), Positives = 50/111 (45%), Gaps = 7/111 (6%)
 Frame = +3

Query: 236 GSPDPTISWFRNGKLIE--ENEKYILKGSNTELTVRNIINKDGGSYVCKATNKAGEDQ-K 292
           G P P I W  N   +E   + ++ L    T L + +  + D G Y C A N AGE    
Sbjct: 6   GKPVPEIVWMHNNNRVEISGDSRFSLLHDGT-LMIEDAQDDDRGVYECIARNVAGETHSN 182

Query: 293 QAFLQVF---VQPHILQLKNETTSENGH-VTLVCEAEGEPVPEITWKRAID 339
           Q  L+ F   V P   Q   +  +  G  V LVC+A G P P  +W R ++
Sbjct: 183 QVELRYFGERVAPXFTQRPQDIVTVEGQTVQLVCQASGHPRPTFSWTRNLE 335

 Score = 48.1 bits (113), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 33/122 (27%), Positives = 49/122 (40%), Gaps = 10/122 (8%)
 Frame = +3

Query: 325 EGEPVPEITWKRAIDGVMFSEGDKSPDGRIEVKGQHGRSSLH-----IRDVKLSDSGRYD 379
           EG+PVPEI W                + R+E+ G    S LH     I D +  D G Y+
Sbjct: 3   EGKPVPEIVWMHN-------------NNRVEISGDSRFSLLHDGTLMIEDAQDDDRGVYE 143

Query: 380 CEAASRIGGHQRSMHLDIEY-----APKFVSNQTMYYSWEGNPINISCDVTANPPASIHW 434
           C  A  + G   S  +++ Y     AP F        + EG  + + C  + +P  +  W
Sbjct: 144 C-IARNVAGETHSNQVELRYFGERVAPXFTQRPQDIVTVEGQTVQLVCQASGHPRPTFSW 320

Query: 435 RR 436
            R
Sbjct: 321 TR 326

 Score = 43.5 bits (101), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 30/111 (27%), Positives = 52/111 (46%), Gaps = 3/111 (2%)
 Frame = +3

Query: 48  PESIDWYNPQGEKIISTQRVMLQKEGVRSRLTIYNANIEDAGIYRCQATDAKGQTQEATV 107
           PE +  +N    +I    R  L  +G    L I +A  +D G+Y C A +  G+T    V
Sbjct: 18  PEIVWMHNNNRVEISGDSRFSLLHDGT---LMIEDAQDDDRGVYECIARNVAGETHSNQV 188

Query: 108 VLEIY-QKLTFREVVSPQEFK--QGEDAEVVCRVSSSPAPAVSWLYHNEEV 155
            L  + +++       PQ+    +G+  ++VC+ S  P P  SW  + E++
Sbjct: 189 ELRYFGERVAPXFTQRPQDIVTVEGQTVQLVCQASGHPRPTFSWTRNLEQL 341
>13135
          Length = 849

 Score = 54.7 bits (130), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 44/168 (26%), Positives = 72/168 (42%), Gaps = 5/168 (2%)
 Frame = -1

Query: 266 LTVRNIINKDGGSYVCKATNKAGEDQKQAFLQVFV--QPHILQLKNET---TSENGHVTL 320
           L ++N    D G Y C+    + ++  +AF Q+ +   P I  L   +    SE   + L
Sbjct: 495 LRIQNGQVTDEGVYTCQV-QLSNQNYAKAFHQLVIIQMPQISDLDTSSDVSKSEGQSLVL 319

Query: 321 VCEAEGEPVPEITWKRAIDGVMFSEGDKSPDGRIEVKGQHGRSSLHIRDVKLSDSGRYDC 380
            C A G P P + W R + G +   G     GR     +H  S L I  +K   +G Y C
Sbjct: 318 RCHASGRPTPSVKWTR-MAGELLPSG-----GR-----EHLESDLVIPQLKPEHAGIYKC 172

Query: 381 EAASRIGGHQRSMHLDIEYAPKFVSNQTMYYSWEGNPINISCDVTANP 428
            +++  G   R++ + + +AP   S  T+    +G    + C V   P
Sbjct: 171 SSSNSAGSDFRNIRVTVNFAPVLSSANTVVQQAQGYVKELVCVVKGYP 28

 Score = 47.0 bits (110), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 46/175 (26%), Positives = 67/175 (38%), Gaps = 7/175 (4%)
 Frame = -1

Query: 77  RLTIYNANIEDAGIYRCQATDAKGQTQEATVVLEIYQKLTFREVVSPQEFKQGEDAEVV- 135
           RL I N  + D G+Y CQ   +     +A   L I Q     ++ +  +  + E   +V 
Sbjct: 498 RLRIQNGQVTDEGVYTCQVQLSNQNYAKAFHQLVIIQMPQISDLDTSSDVSKSEGQSLVL 319

Query: 136 -CRVSSSPAPAVSWLYHNEEVTTIPDNRFAVLAXXXXXXXXXXKSDEGIYRCEGRVEARG 194
            C  S  P P+V W     E+  +P      L           +   GIY+C     A  
Sbjct: 318 RCHASGRPTPSVKWTRMAGEL--LPSGGREHLESDLVIPQLKPE-HAGIYKCSSSNSAGS 148

Query: 195 EIDFRDIIVIVNVPPAIMMPQKSFNATAERGEEMT--LTCKASGSPDPT---ISW 244
             DFR+I V VN  P +     S N   ++ +     L C   G P P    I+W
Sbjct: 147 --DFRNIRVTVNFAPVL----SSANTVVQQAQGYVKELVCVVKGYPTPKADDITW 1

 Score = 42.0 bits (97), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 38/119 (31%), Positives = 51/119 (42%), Gaps = 2/119 (1%)
 Frame = -1

Query: 28  SKVELSVGESKFFTCTAIGEPE-SIDWYNPQGEKIISTQRVMLQKEGVRSRLTIYNANIE 86
           S V  S G+S    C A G P  S+ W    GE + S  R     E + S L I     E
Sbjct: 357 SDVSKSEGQSLVLRCHASGRPTPSVKWTRMAGELLPSGGR-----EHLESDLVIPQLKPE 193

Query: 87  DAGIYRCQATDAKGQT-QEATVVLEIYQKLTFREVVSPQEFKQGEDAEVVCRVSSSPAP 144
            AGIY+C ++++ G   +   V +     L+    V  Q   QG   E+VC V   P P
Sbjct: 192 HAGIYKCSSSNSAGSDFRNIRVTVNFAPVLSSANTVVQQ--AQGYVKELVCVVKGYPTP 22
>11855
          Length = 1574

 Score = 49.7 bits (117), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 32/90 (35%), Positives = 50/90 (55%), Gaps = 7/90 (7%)
 Frame = +1

Query: 214 PQKSFNATAERGEEMTLT----CKASGSPDPTISWF--RNGKLIEENEKYILKGSNTELT 267
           P + +  T  R E  T T    C+ASG P+PTI+W+  RN  L + + ++ +   N +L 
Sbjct: 313 PARVYMWTVSRLELETTTVQLFCRASGYPEPTITWYDGRNNSLPDNSGQFSI-AVNGDLI 489

Query: 268 VRNI-INKDGGSYVCKATNKAGEDQKQAFL 296
           +R+I  +++ G Y C A N+ G    QAFL
Sbjct: 490 IRDISWSENMGVYRCVAENELGSHSVQAFL 579

 Score = 43.1 bits (100), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 49/199 (24%), Positives = 74/199 (37%), Gaps = 45/199 (22%)
 Frame = +1

Query: 236 GSPDPTISWFRNGKLIEENE---------------------KYILKGSNTELTVRNIINK 274
           GSP PTI W ++G  + ++                      +  L  + + L +    ++
Sbjct: 1   GSPVPTIHWLKDGVRLTQSTYETVDDESALYEDLASDPGQPRLRLSSTKSRLYLDCPTSQ 180

Query: 275 DGGSYVCKATNKAGEDQKQAFLQVFVQPH-----------------------ILQLKNET 311
           D G Y C A        +   ++V  + +                       + +L+ ET
Sbjct: 181 DEGEYTCVAETPFKRRVQSTIVKVDTRHYSPDVTCMSKRGSRGEPARVYMWTVSRLELET 360

Query: 312 TSENGHVTLVCEAEGEPVPEITWKRAIDGVMFSEGDKSPDGRIEVKGQHGRSSLHIRDVK 371
           T+    V L C A G P P ITW    DG   S  D S    I V G      L IRD+ 
Sbjct: 361 TT----VQLFCRASGYPEPTITW---YDGRNNSLPDNSGQFSIAVNGD-----LIIRDIS 504

Query: 372 LSDS-GRYDCEAASRIGGH 389
            S++ G Y C A + +G H
Sbjct: 505 WSENMGVYRCVAENELGSH 561

 Score = 30.0 bits (66), Expect = 3.8,   Method: Compositional matrix adjust.
 Identities = 30/138 (21%), Positives = 53/138 (38%), Gaps = 20/138 (14%)
 Frame = +1

Query: 69  LQKEGVRSRLTIYNANIEDAGIYRCQATDAKGQTQEATVVLEIYQKLTFREVVSPQEFKQ 128
           L+    +SRL +     +D G Y C A     +  ++T+V    +  +       +   +
Sbjct: 127 LRLSSTKSRLYLDCPTSQDEGEYTCVAETPFKRRVQSTIVKVDTRHYSPDVTCMSKRGSR 306

Query: 129 GEDAEV-----------------VCRVSSSPAPAVSWLYHNEEVTTIPDN--RFAVLAXX 169
           GE A V                  CR S  P P ++W  ++    ++PDN  +F++    
Sbjct: 307 GEPARVYMWTVSRLELETTTVQLFCRASGYPEPTITW--YDGRNNSLPDNSGQFSIAVNG 480

Query: 170 XXXXXXXXKSDE-GIYRC 186
                    S+  G+YRC
Sbjct: 481 DLIIRDISWSENMGVYRC 534
>37675
          Length = 741

 Score = 49.7 bits (117), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 29/80 (36%), Positives = 41/80 (51%), Gaps = 1/80 (1%)
 Frame = +2

Query: 205 VNVPPAIMMPQKSFNATAERGEEMTLTCKASGSPDPTISW-FRNGKLIEENEKYILKGSN 263
           V +PP + +   S    A    +M   C A G P PTISW F N  + E+ + Y L+ +N
Sbjct: 59  VQMPPVVKVSPHSLIYPARLNAKMK--CHAEGVPKPTISWLFNNVPISEDPQHYDLESAN 232

Query: 264 TELTVRNIINKDGGSYVCKA 283
             L V N  ++D G+Y C A
Sbjct: 233 ELLVVYNAGDQDTGAYKCVA 292

 Score = 33.9 bits (76), Expect = 0.23,   Method: Compositional matrix adjust.
 Identities = 23/102 (22%), Positives = 41/102 (40%), Gaps = 2/102 (1%)
 Frame = +2

Query: 91  YRCQ-ATDAKG-QTQEATVVLEIYQKLTFREVVSPQEFKQGEDAEVVCRVSSSPAPAVSW 148
           Y C+ +TD    Q     V +    K++   ++ P       +A++ C     P P +SW
Sbjct: 5   YSCEDSTDPSSLQVHALKVQMPPVVKVSPHSLIYPARL----NAKMKCHAEGVPKPTISW 172

Query: 149 LYHNEEVTTIPDNRFAVLAXXXXXXXXXXKSDEGIYRCEGRV 190
           L++N  ++  P +     A            D G Y+C  R+
Sbjct: 173 LFNNVPISEDPQHYDLESANELLVVYNAGDQDTGAYKCVARI 298

 Score = 29.6 bits (65), Expect = 4.6,   Method: Compositional matrix adjust.
 Identities = 21/71 (29%), Positives = 30/71 (42%)
 Frame = +2

Query: 322 CEAEGEPVPEITWKRAIDGVMFSEGDKSPDGRIEVKGQHGRSSLHIRDVKLSDSGRYDCE 381
           C AEG P P I+W    + V  SE  +  D       +     L + +    D+G Y C 
Sbjct: 134 CHAEGVPKPTISW--LFNNVPISEDPQHYD------LESANELLVVYNAGDQDTGAYKCV 289

Query: 382 AASRIGGHQRS 392
           A  R+  H+ S
Sbjct: 290 ARIRLVPHKTS 322
>27666
          Length = 873

 Score = 48.1 bits (113), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 38/128 (29%), Positives = 55/128 (42%), Gaps = 7/128 (5%)
 Frame = +1

Query: 266 LTVRNIINKDGGSYVCKAT----NKAGEDQKQAFLQVFVQPHILQLKNETTSE---NGHV 318
           L +R +  +D G+YVC+      N   + QK   L V V P I   +  T  E   N + 
Sbjct: 394 LVIRRLRQQDAGTYVCQVKIQNENILSQVQKIGTLTVQVPPKIRPGETTTLVEIDQNQNS 573

Query: 319 TLVCEAEGEPVPEITWKRAIDGVMFSEGDKSPDGRIEVKGQHGRSSLHIRDVKLSDSGRY 378
           +LVC + G P P ITW R        +G   P G  + +G+     L +    +   G Y
Sbjct: 574 SLVCSSTGIPAPNITWTRL-------DGRALPTGYSQFRGRE----LPLNGATVDHMGVY 720

Query: 379 DCEAASRI 386
            C A + I
Sbjct: 721 RCVANNNI 744

 Score = 35.8 bits (81), Expect = 0.063,   Method: Compositional matrix adjust.
 Identities = 21/76 (27%), Positives = 37/76 (48%), Gaps = 5/76 (6%)
 Frame = +1

Query: 78  LTIYNANIEDAGIYRCQAT----DAKGQTQE-ATVVLEIYQKLTFREVVSPQEFKQGEDA 132
           L I     +DAG Y CQ      +   Q Q+  T+ +++  K+   E  +  E  Q +++
Sbjct: 394 LVIRRLRQQDAGTYVCQVKIQNENILSQVQKIGTLTVQVPPKIRPGETTTLVEIDQNQNS 573

Query: 133 EVVCRVSSSPAPAVSW 148
            +VC  +  PAP ++W
Sbjct: 574 SLVCSSTGIPAPNITW 621

 Score = 34.7 bits (78), Expect = 0.16,   Method: Compositional matrix adjust.
 Identities = 32/136 (23%), Positives = 57/136 (41%), Gaps = 4/136 (2%)
 Frame = +1

Query: 178 KSDEGIYRCEGRVEARGEIDFRDII--VIVNVPPAIMMPQKSFNATAERGEEMTLTCKAS 235
           + D G Y C+ +++    +     I  + V VPP I   + +     ++ +  +L C ++
Sbjct: 415 QQDAGTYVCQVKIQNENILSQVQKIGTLTVQVPPKIRPGETTTLVEIDQNQNSSLVCSST 594

Query: 236 GSPDPTISWFR-NGKLIEENEKYILKGSNTELTVRNIINKDGGSYVCKATNKAG-EDQKQ 293
           G P P I+W R +G+ +        +G   EL +        G Y C A N     D   
Sbjct: 595 GIPAPNITWTRLDGRALPTGYSQ-FRGR--ELPLNGATVDHMGVYRCVANNNIKPPDDHL 765

Query: 294 AFLQVFVQPHILQLKN 309
             ++VF  P    ++N
Sbjct: 766 CEVRVFHAPTARTVQN 813
>25455
          Length = 444

 Score = 45.4 bits (106), Expect = 8e-05,   Method: Compositional matrix adjust.
 Identities = 34/126 (26%), Positives = 57/126 (45%), Gaps = 10/126 (7%)
 Frame = +1

Query: 184 YRCEGRVEARGEIDF--RDIIVIVNVPPA-IMMPQKSFNATAERGEEMTLTCKASGSPDP 240
           YRC         I+F  R++ V+V   P+ ++ PQ +     E GE   +TC A+  PDP
Sbjct: 1   YRCWAESTVH-HINFPLREMRVVVQSAPSWVVAPQVT---EVEVGETAEITCNATAIPDP 168

Query: 241 TISWFRNGKLIEENEKYILKG-------SNTELTVRNIINKDGGSYVCKATNKAGEDQKQ 293
             +WF NG+ I +  ++ ++        ++  L +RN+  +      C  TN+ G     
Sbjct: 169 VTNWFVNGREISDVVEHDVRFQSGRFDLTSDRLILRNVTIEGRMVVQCNVTNRYGHLWAD 348

Query: 294 AFLQVF 299
             L V 
Sbjct: 349 VSLNVL 366

 Score = 29.3 bits (64), Expect = 6.2,   Method: Compositional matrix adjust.
 Identities = 20/76 (26%), Positives = 32/76 (42%), Gaps = 5/76 (6%)
 Frame = +1

Query: 31  ELSVGESKFFTCTAIGEPESIDWYNPQGEKI--ISTQRVMLQK---EGVRSRLTIYNANI 85
           E+ VGE+   TC A   P+ +  +   G +I  +    V  Q    +    RL + N  I
Sbjct: 109 EVEVGETAEITCNATAIPDPVTNWFVNGREISDVVEHDVRFQSGRFDLTSDRLILRNVTI 288

Query: 86  EDAGIYRCQATDAKGQ 101
           E   + +C  T+  G 
Sbjct: 289 EGRMVVQCNVTNRYGH 336
>06028
          Length = 1358

 Score = 45.1 bits (105), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 55/242 (22%), Positives = 92/242 (38%), Gaps = 26/242 (10%)
 Frame = +1

Query: 76  SRLTIYNANIEDAGIYRCQATDAKGQTQEATVV---------LEIYQKLTFREVVSPQEF 126
           S+L I+N   +D+G+Y C A++   Q + +  V         LE       R+   P  F
Sbjct: 79  SKLIIHNPVEKDSGVYFCVASNEGAQNKISHQVDFKGRERFTLEKTAGFFHRDPNKPH-F 255

Query: 127 KQGEDAEVVCR----------VSSSPAPAVSWLYHNEEVTTIPDNRFAVLAXXXXXXXXX 176
                 + VC           + SS    V WL +   V       F             
Sbjct: 256 LNPLGNQTVCHGGTVAISAEFMQSSTPIEVKWLRNRRPVDGPSVQTFNERGIYTLAIMNA 435

Query: 177 XKSDEGIYRCE-----GRVEARGEIDFRDIIVIVNVPPAIMMPQKSFNATAERGEEMTLT 231
            +  EG Y C      GR+E+   ID   + V   V P + + +         G+  +L+
Sbjct: 436 GEEHEGTYTCLASNAFGRIESHVNIDVA-VGVEKEVRPPLFLSRPETEMKIAVGDPFSLS 612

Query: 232 CKASGSPDPTISWFRNGKLIEENEKYILKGSN--TELTVRNIINKDGGSYVCKATNKAGE 289
            + +G P P + + +  K I ++++   + S+  T  TV+     D G+Y   A N  G 
Sbjct: 613 FRIAGDPKPRLVFMKGTKDITQSDRVSKEVSDDYTRFTVQKSQISDSGTYFVVARNDFGT 792

Query: 290 DQ 291
           D+
Sbjct: 793 DR 798
>38127
          Length = 860

 Score = 40.4 bits (93), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 28/111 (25%), Positives = 46/111 (41%), Gaps = 11/111 (9%)
 Frame = -1

Query: 182 GIYRCEGRVEARGEIDFRDIIVIVNVPPAIMMPQKSFNATAERGEEMTLTCKASGSPDPT 241
           G+Y C    E  G      + V     P ++   KS N   +  E + + CK  G P P 
Sbjct: 764 GMYTCVAEYEEAGVKSSISVDVPFYAHPKVLPFDKSKNLVQD--ESLVIECKVLGYPKPV 591

Query: 242 ISWFRNGKLIEE--NEKYILKGSNT---------ELTVRNIINKDGGSYVC 281
           +SW+ +   I +  + +Y LK +N+         +L +  +   D G Y C
Sbjct: 590 VSWYMDNVEIVDGADSRYSLKPANSYDGASIEGAKLVIEEVQFDDAGEYTC 438

 Score = 34.3 bits (77), Expect = 0.18,   Method: Compositional matrix adjust.
 Identities = 21/79 (26%), Positives = 33/79 (41%), Gaps = 1/79 (1%)
 Frame = -1

Query: 88  AGIYRCQAT-DAKGQTQEATVVLEIYQKLTFREVVSPQEFKQGEDAEVVCRVSSSPAPAV 146
           AG+Y C A  +  G     +V +  Y           +   Q E   + C+V   P P V
Sbjct: 767 AGMYTCVAEYEEAGVKSSISVDVPFYAHPKVLPFDKSKNLVQDESLVIECKVLGYPKPVV 588

Query: 147 SWLYHNEEVTTIPDNRFAV 165
           SW   N E+    D+R+++
Sbjct: 587 SWYMDNVEIVDGADSRYSL 531

 Score = 30.8 bits (68), Expect = 2.1,   Method: Compositional matrix adjust.
 Identities = 28/132 (21%), Positives = 50/132 (37%), Gaps = 13/132 (9%)
 Frame = -1

Query: 359 QHGRSSLHIRDVKLSDSGRYDCEAASRIGGHQRSMHLDIEYA--PKFVSNQTMYYSWEGN 416
           QH   +L I+  + + +G Y C A     G + S+ +D+ +   PK +         +  
Sbjct: 815 QHNNGTLEIQHPRRNFAGMYTCVAEYEEAGVKSSISVDVPFYAHPKVLPFDKSKNLVQDE 636

Query: 417 PINISCDVTANPPASIHWRREKL-----------LLPAKNTTHLKTHSVGRKMILEIAPT 465
            + I C V   P   + W  + +           L PA +         G K+++E    
Sbjct: 635 SLVIECKVLGYPKPVVSWYMDNVEIVDGADSRYSLKPANSYDGASIE--GAKLVIE--EV 468

Query: 466 SDNDFGRYNCTA 477
             +D G Y C +
Sbjct: 467 QFDDAGEYTCMS 432
>36498
          Length = 478

 Score = 30.4 bits (67), Expect(2) = 0.005,   Method: Composition-based stats.
 Identities = 17/55 (30%), Positives = 24/55 (43%)
 Frame = +1

Query: 192 ARGEIDFRDIIVIVNVPPAIMMPQKSFNATAERGEEMTLTCKASGSPDPTISWFR 246
           A G +     +VI   P   + P      TA  G+ + + C A G P PT+ W R
Sbjct: 4   AAGTVTLTASLVIQGPPTVTVTPGTRI--TALVGDRVDIECVAEGDPTPTVFWRR 162

 Score = 28.1 bits (61), Expect(2) = 0.005,   Method: Composition-based stats.
 Identities = 21/67 (31%), Positives = 28/67 (41%), Gaps = 5/67 (7%)
 Frame = +3

Query: 275 DGGSYVCKATNKAGEDQKQAFLQVF-----VQPHILQLKNETTSENGHVTLVCEAEGEPV 329
           D G YVC A N+ G  ++   L V       Q +I     +   +   V L C A G   
Sbjct: 258 DAGRYVCVARNERGITEENVDLTVTRTGVAPQVNIDGPGRQMLVDGQSVELSCSARGLRN 437

Query: 330 PEITWKR 336
           P I W+R
Sbjct: 438 PLIRWRR 458

 Score = 27.7 bits (60), Expect(2) = 0.13,   Method: Composition-based stats.
 Identities = 9/19 (47%), Positives = 13/19 (68%)
 Frame = +1

Query: 318 VTLVCEAEGEPVPEITWKR 336
           V + C AEG+P P + W+R
Sbjct: 106 VDIECVAEGDPTPTVFWRR 162

 Score = 25.8 bits (55), Expect(2) = 0.13,   Method: Composition-based stats.
 Identities = 20/80 (25%), Positives = 32/80 (40%), Gaps = 4/80 (5%)
 Frame = +3

Query: 361 GRSSLHIRDVKLSDSGRYDCEAASRIGGHQRSMHLDIE---YAPKF-VSNQTMYYSWEGN 416
           G + L    V   D+GRY C A +  G  + ++ L +     AP+  +         +G 
Sbjct: 219 GTAGLRFDPVSEGDAGRYVCVARNERGITEENVDLTVTRTGVAPQVNIDGPGRQMLVDGQ 398

Query: 417 PINISCDVTANPPASIHWRR 436
            + +SC         I WRR
Sbjct: 399 SVELSCSARGLRNPLIRWRR 458

 Score = 25.8 bits (55), Expect(2) = 1.2,   Method: Composition-based stats.
 Identities = 11/23 (47%), Positives = 12/23 (52%)
 Frame = +3

Query: 460 LEIAPTSDNDFGRYNCTATNRIG 482
           L   P S+ D GRY C A N  G
Sbjct: 231 LRFDPVSEGDAGRYVCVARNERG 299

 Score = 24.3 bits (51), Expect(2) = 1.2,   Method: Composition-based stats.
 Identities = 7/22 (31%), Positives = 13/22 (59%)
 Frame = +1

Query: 415 GNPINISCDVTANPPASIHWRR 436
           G+ ++I C    +P  ++ WRR
Sbjct: 97  GDRVDIECVAEGDPTPTVFWRR 162
>25766
          Length = 469

 Score = 38.9 bits (89), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 20/76 (26%), Positives = 37/76 (48%), Gaps = 2/76 (2%)
 Frame = +1

Query: 266 LTVRNIINKDGGSYVCKATNKAG-EDQKQAFLQVFVQPHI-LQLKNETTSENGHVTLVCE 323
           L +  +   D G Y C  T+  G   +  A L++   P + ++ +NE       V   C+
Sbjct: 67  LQIPRVTAADAGRYRCVITSSEGITSEGFATLRISSPPVVSVKQRNENRQVGSSVKFHCD 246

Query: 324 AEGEPVPEITWKRAID 339
             G+PVP++ W++ +D
Sbjct: 247 VSGDPVPQVRWEKKVD 294

 Score = 35.4 bits (80), Expect = 0.084,   Method: Compositional matrix adjust.
 Identities = 22/71 (30%), Positives = 27/71 (38%)
 Frame = +1

Query: 78  LTIYNANIEDAGIYRCQATDAKGQTQEATVVLEIYQKLTFREVVSPQEFKQGEDAEVVCR 137
           L I      DAG YRC  T ++G T E    L I            +  + G   +  C 
Sbjct: 67  LQIPRVTAADAGRYRCVITSSEGITSEGFATLRISSPPVVSVKQRNENRQVGSSVKFHCD 246

Query: 138 VSSSPAPAVSW 148
           VS  P P V W
Sbjct: 247 VSGDPVPQVRW 279

 Score = 30.8 bits (68), Expect = 2.2,   Method: Compositional matrix adjust.
 Identities = 20/74 (27%), Positives = 29/74 (39%), Gaps = 1/74 (1%)
 Frame = +1

Query: 365 LHIRDVKLSDSGRYDCEAASRIGGHQRSMH-LDIEYAPKFVSNQTMYYSWEGNPINISCD 423
           L I  V  +D+GRY C   S  G        L I   P     Q       G+ +   CD
Sbjct: 67  LQIPRVTAADAGRYRCVITSSEGITSEGFATLRISSPPVVSVKQRNENRQVGSSVKFHCD 246

Query: 424 VTANPPASIHWRRE 437
           V+ +P   + W ++
Sbjct: 247 VSGDPVPQVRWEKK 288

 Score = 29.6 bits (65), Expect = 4.9,   Method: Compositional matrix adjust.
 Identities = 20/71 (28%), Positives = 31/71 (43%), Gaps = 5/71 (7%)
 Frame = +1

Query: 179 SDEGIYRC-----EGRVEARGEIDFRDIIVIVNVPPAIMMPQKSFNATAERGEEMTLTCK 233
           +D G YRC     EG + + G    R     ++ PP + + Q+  N   + G  +   C 
Sbjct: 91  ADAGRYRCVITSSEG-ITSEGFATLR-----ISSPPVVSVKQR--NENRQVGSSVKFHCD 246

Query: 234 ASGSPDPTISW 244
            SG P P + W
Sbjct: 247 VSGDPVPQVRW 279
>11732
          Length = 640

 Score = 37.7 bits (86), Expect = 0.015,   Method: Composition-based stats.
 Identities = 33/125 (26%), Positives = 55/125 (44%), Gaps = 4/125 (3%)
 Frame = +2

Query: 266 LTVRNIINKDGGSYVCKATNKAGEDQKQAFLQVFVQPHILQLKNETTSENGHVTLVCEAE 325
           L+  ++   D G Y CK+T+   +  +   L V ++P I +  +  T  +G    VC AE
Sbjct: 50  LSFSDLSMDDAGLYQCKSTSGMEQVIRNITLFVVLEPQIKRNMSTFTMLDGIAEAVCVAE 229

Query: 326 GEPVPEITWKRAIDGVMFSEGDKSPDGRIEVKGQHG---RSSLHIRDVKLSDSGR-YDCE 381
           G+P P   ++    G      D S    IEV        R+ L + D  ++   R  +CE
Sbjct: 230 GDPAPTFLFR----GNHVELSDDSEGHDIEVTQLDALTWRAVLRVTDSTVASGLRQVECE 397

Query: 382 AASRI 386
           A + +
Sbjct: 398 ARNEM 412

 Score = 30.4 bits (67), Expect = 2.6,   Method: Composition-based stats.
 Identities = 22/91 (24%), Positives = 40/91 (43%), Gaps = 7/91 (7%)
 Frame = +2

Query: 78  LTIYNANIEDAGIYRCQATDAKGQTQEATVVLEIYQKLTFREVVSPQEFKQGED------ 131
           L+  + +++DAG+Y+C++T    Q         + + +T   V+ PQ  +          
Sbjct: 50  LSFSDLSMDDAGLYQCKSTSGMEQ---------VIRNITLFVVLEPQIKRNMSTFTMLDG 202

Query: 132 -AEVVCRVSSSPAPAVSWLYHNEEVTTIPDN 161
            AE VC     PAP  ++L+    V    D+
Sbjct: 203 IAEAVCVAEGDPAP--TFLFRGNHVELSDDS 289
>19356
          Length = 451

 Score = 37.4 bits (85), Expect = 0.020,   Method: Compositional matrix adjust.
 Identities = 17/53 (32%), Positives = 28/53 (52%), Gaps = 2/53 (3%)
 Frame = -2

Query: 241 TISWFRNGKLIEENEKY--ILKGSNTELTVRNIINKDGGSYVCKATNKAGEDQ 291
            I WF+NG+ +    ++  +       L +  +I++D G Y C A NKAG+ Q
Sbjct: 183 VIEWFKNGRPLNNGCRFNIVFDRGFAILDIIGVISEDTGDYFCFARNKAGQAQ 25
>18345
          Length = 461

 Score = 37.4 bits (85), Expect = 0.023,   Method: Composition-based stats.
 Identities = 31/139 (22%), Positives = 54/139 (38%)
 Frame = +1

Query: 78  LTIYNANIEDAGIYRCQATDAKGQTQEATVVLEIYQKLTFREVVSPQEFKQGEDAEVVCR 137
           L I +  + D G+Y C+      Q ++ T+V+++   +           K+G+ A +VC 
Sbjct: 4   LLIRHVRLNDTGVYECRINTQPSQIKQVTLVVQVPPVVLSEGSPDRVSLKEGDTATLVCN 183

Query: 138 VSSSPAPAVSWLYHNEEVTTIPDNRFAVLAXXXXXXXXXXKSDEGIYRCEGRVEARGEID 197
           V+  P+P V+W   N         R                 D+ IY C         + 
Sbjct: 184 VTGVPSPDVTWYKRNTRQLDAQKERVGSTGPVLVMYNVTRHCDD-IYECYADNGVPPAVT 360

Query: 198 FRDIIVIVNVPPAIMMPQK 216
            + I V V+  P + +P K
Sbjct: 361 -KAIRVTVDYAPEVHLPTK 414

 Score = 32.7 bits (73), Expect = 0.54,   Method: Composition-based stats.
 Identities = 15/63 (23%), Positives = 28/63 (44%)
 Frame = +1

Query: 223 ERGEEMTLTCKASGSPDPTISWFRNGKLIEENEKYILKGSNTELTVRNIINKDGGSYVCK 282
           + G+  TL C  +G P P ++W++      + +K  +  +   L + N+       Y C 
Sbjct: 151 KEGDTATLVCNVTGVPSPDVTWYKRNTRQLDAQKERVGSTGPVLVMYNVTRHCDDIYECY 330

Query: 283 ATN 285
           A N
Sbjct: 331 ADN 339

 Score = 29.6 bits (65), Expect = 4.8,   Method: Composition-based stats.
 Identities = 29/140 (20%), Positives = 58/140 (41%), Gaps = 3/140 (2%)
 Frame = +1

Query: 266 LTVRNIINKDGGSYVCKATNKAGEDQKQAFLQVFVQPHILQLKNETTS--ENGHVTLVCE 323
           L +R++   D G Y C+   +  + ++   +       + +   +  S  E    TLVC 
Sbjct: 4   LLIRHVRLNDTGVYECRINTQPSQIKQVTLVVQVPPVVLSEGSPDRVSLKEGDTATLVCN 183

Query: 324 AEGEPVPEITWKRAIDGVMFSEGDKSPDGRIEVKGQHGRSSLHIRDVKLSDSGRYDCEAA 383
             G P P++TW        +    +  D + E  G  G   L + +V       Y+C A 
Sbjct: 184 VTGVPSPDVTW--------YKRNTRQLDAQKERVGSTG-PVLVMYNVTRHCDDIYECYAD 336

Query: 384 SRI-GGHQRSMHLDIEYAPK 402
           + +     +++ + ++YAP+
Sbjct: 337 NGVPPAVTKAIRVTVDYAPE 396
>17530
          Length = 503

 Score = 36.2 bits (82), Expect = 0.045,   Method: Compositional matrix adjust.
 Identities = 36/147 (24%), Positives = 59/147 (40%), Gaps = 10/147 (6%)
 Frame = +2

Query: 294 AFLQVFVQPHILQLKNETTS----ENGHVTLVCEAEG-EPVPEITWKRAIDGVMFSEGDK 348
           A L V + P    + ++ T     E   V   C + G  P P ITW +  +GV    G +
Sbjct: 32  ANLTVLLPPGPPSITSDITGDVFEEGQRVRFTCSSSGGNPPPTITWTK--NGVQLINGVQ 205

Query: 349 SPD-GRIEVKGQHGRSSLHIRDVKLSDSGRYDCEAASRIGGHQR---SMHLDIEYAPKFV 404
               G+    G   R+++ +          Y C   +++  +     S+ L++ Y+P   
Sbjct: 206 QIGVGQTSTSGGSTRNTVSVVMDHSDHQANYTCFVYNQVNINSSLTASVVLNVRYSPIIT 385

Query: 405 SNQ-TMYYSWEGNPINISCDVTANPPA 430
               + Y      P NI+C V ANPP 
Sbjct: 386 FEPFSPYIVRLDRPANITCQVDANPPC 466

 Score = 32.3 bits (72), Expect = 0.78,   Method: Compositional matrix adjust.
 Identities = 13/27 (48%), Positives = 19/27 (70%), Gaps = 1/27 (3%)
 Frame = +2

Query: 223 ERGEEMTLTCKASG-SPDPTISWFRNG 248
           E G+ +  TC +SG +P PTI+W +NG
Sbjct: 101 EEGQRVRFTCSSSGGNPPPTITWTKNG 181
>32888
          Length = 418

 Score = 35.4 bits (80), Expect = 0.073,   Method: Compositional matrix adjust.
 Identities = 11/29 (37%), Positives = 20/29 (68%)
 Frame = -3

Query: 223 ERGEEMTLTCKASGSPDPTISWFRNGKLI 251
           + G+ + L C+A G P P ++W++NG +I
Sbjct: 239 DEGQTVRLDCRAKGKPSPKVTWYKNGHII 153

 Score = 30.0 bits (66), Expect(2) = 0.68,   Method: Compositional matrix adjust.
 Identities = 15/40 (37%), Positives = 25/40 (62%)
 Frame = -3

Query: 318 VTLVCEAEGEPVPEITWKRAIDGVMFSEGDKSPDGRIEVK 357
           V L C A+G+P P++TW +  +G + + GD     R+E+K
Sbjct: 224 VRLDCRAKGKPSPKVTWYK--NGHIITNGDD----RVEIK 123

 Score = 20.8 bits (42), Expect(2) = 0.68,   Method: Composition-based stats.
 Identities = 9/37 (24%), Positives = 18/37 (48%)
 Frame = -2

Query: 362 RSSLHIRDVKLSDSGRYDCEAASRIGGHQRSMHLDIE 398
           +  L I+ +   D G Y C  ++  G    + ++D+E
Sbjct: 123 KYKLTIKSLGAEDKGNYTCIVSNTEGQIDWTFYVDVE 13
>29932
          Length = 748

 Score = 35.0 bits (79), Expect = 0.12,   Method: Compositional matrix adjust.
 Identities = 21/66 (31%), Positives = 30/66 (45%)
 Frame = +3

Query: 418 INISCDVTANPPASIHWRREKLLLPAKNTTHLKTHSVGRKMILEIAPTSDNDFGRYNCTA 477
           I I CDVT   P ++ W  +    P   + H+         IL     +  D G Y+CTA
Sbjct: 147 IEIYCDVTNARPENVQWATDN-NRPLPGSVHIDGQ------ILRFVAITPADAGGYSCTA 305

Query: 478 TNRIGT 483
           +N+ GT
Sbjct: 306 SNKYGT 323
>19544
          Length = 1421

 Score = 34.3 bits (77), Expect = 0.20,   Method: Compositional matrix adjust.
 Identities = 40/184 (21%), Positives = 80/184 (43%), Gaps = 6/184 (3%)
 Frame = +2

Query: 499 PHGVKIIELSQTTAKISFNKP---ESHGGVPIHHYQVDVKEVASETWKIVRSHGVQTMVV 555
           P  V+ +  S ++ ++++  P     +GG  +  Y+V   + +S   + +     +T ++
Sbjct: 116 PSNVQAVNKSASSIQVTWVAPPPETQNGG--LSGYKVLYYKQSSSAEEELTRITAETHIL 289

Query: 556 LSSLEPNTTYEIRVAAVNGKGQGDYSKIEIFQTLPVREPSPPSIHGQPSSGKSFKISITK 615
           L SLE  T Y I V   N  G+G  S +   QT      +P SI     + +   +    
Sbjct: 290 LESLETFTVYFIAVQPYNLAGEGPRSALVSAQTSEGVPSAPQSIRFTNITMRQLMVHFDP 469

Query: 616 QDDGGAPILEYIVKYRSKDKEDQWL---EKKVQGNKDHIILEHLQWTMGYEVQITAANRL 672
                  IL Y ++Y  KD+        ++ ++ N+  +++  L+  + Y+  I+A   +
Sbjct: 470 PTTPNGHILLYEMQYFPKDESRYGFLAPKRILRANETRVVVTELEKRVWYKFIISANTSI 649

Query: 673 GYSE 676
           G  E
Sbjct: 650 GKGE 661

 Score = 32.3 bits (72), Expect = 0.75,   Method: Compositional matrix adjust.
 Identities = 30/117 (25%), Positives = 52/117 (44%), Gaps = 7/117 (5%)
 Frame = +2

Query: 564 TYEIRVAAVNGKGQGDYS---KIEIFQTLPVREPSPPSIHGQPSSGKSFKISIT----KQ 616
           TYE++V AVNGKG+G  S    I + +  P   PS  ++     S  S +++      + 
Sbjct: 17  TYEVQVLAVNGKGRGPPSTPATIYVGEAAPTEGPS--NVQAVNKSASSIQVTWVAPPPET 190

Query: 617 DDGGAPILEYIVKYRSKDKEDQWLEKKVQGNKDHIILEHLQWTMGYEVQITAANRLG 673
            +GG    + +   +S   E++      +    HI+LE L+    Y + +   N  G
Sbjct: 191 QNGGLSGYKVLYYKQSSSAEEELTRITAE---THILLESLETFTVYFIAVQPYNLAG 352

 Score = 30.8 bits (68), Expect = 2.2,   Method: Compositional matrix adjust.
 Identities = 14/25 (56%), Positives = 16/25 (64%)
 Frame = +2

Query: 557 SSLEPNTTYEIRVAAVNGKGQGDYS 581
           SSL PNT Y+ RV A+N  G  D S
Sbjct: 890 SSLNPNTGYQFRVMAINDDGISDES 964
>36700
          Length = 595

 Score = 34.3 bits (77), Expect = 0.20,   Method: Compositional matrix adjust.
 Identities = 31/117 (26%), Positives = 46/117 (39%), Gaps = 4/117 (3%)
 Frame = +1

Query: 329 VPEITWKRAIDGVMFSEGDKSPDGRIEVKGQHGRSSLHIRDVKLSDSGRYDCEAASRIGG 388
           VP ITW         S    S  GR  ++  +GR  L I +V   D   Y C+  +  G 
Sbjct: 64  VPAITWWET------STDQISTGGRFSIE-DNGRV-LVIDNVDEQDEKTYTCKGENPAGS 219

Query: 389 HQRSMHLDIEYAPKFVSNQTMYYSWEGNPINISCDVTA----NPPASIHWRREKLLL 441
           H  ++HL++   P F+ +       +G     +C   +     PP    W R  L L
Sbjct: 220 HSGNLHLNVTSPPIFMQHLQSLTVPQGKDAYFNCVTRSASGEKPPNPPTWYRNGLRL 390
>10921
          Length = 525

 Score = 33.9 bits (76), Expect = 0.21,   Method: Composition-based stats.
 Identities = 27/90 (30%), Positives = 40/90 (44%), Gaps = 2/90 (2%)
 Frame = -2

Query: 247 NGKLIEENEKYILKGSNTELTVRNIINKDGGSYVCKATNKAGEDQKQAFLQVFVQPHILQ 306
           N + + E   YI+ G+   L + N+   D   Y CKA    G +    FL V   P  L 
Sbjct: 470 NDRPVGEGGHYIISGT-YNLIIVNVTLNDQAEYTCKA----GSESYFGFLTVIDLPQNLT 306

Query: 307 LKNETT-SENGHVTLVCEA-EGEPVPEITW 334
           ++ ETT + +    L C A    P P ++W
Sbjct: 305 VQWETTPTPSSTSNLSCVASRAHPPPPLSW 216

 Score = 28.9 bits (63), Expect = 6.8,   Method: Composition-based stats.
 Identities = 17/71 (23%), Positives = 33/71 (46%), Gaps = 1/71 (1%)
 Frame = -2

Query: 179 SDEGIYRCEGRVEARGEIDFRDIIVIVNVPPAIMMPQKSFNATAERGEEMTLTCKAS-GS 237
           +D+  Y C+   E+     +   + ++++P  + +    +  T        L+C AS   
Sbjct: 392 NDQAEYTCKAGSES-----YFGFLTVIDLPQNLTV---QWETTPTPSSTSNLSCVASRAH 237

Query: 238 PDPTISWFRNG 248
           P P +SWF+NG
Sbjct: 236 PPPPLSWFKNG 204
>12764
          Length = 1055

 Score = 33.5 bits (75), Expect = 0.35,   Method: Compositional matrix adjust.
 Identities = 22/63 (34%), Positives = 30/63 (47%)
 Frame = +1

Query: 223 ERGEEMTLTCKASGSPDPTISWFRNGKLIEENEKYILKGSNTELTVRNIINKDGGSYVCK 282
           E G  + LTC   G+P P +  +R     +E E   L   NT LT+ N+   D G+Y C 
Sbjct: 265 EEGLNLDLTCITQGNPLPFLVEWR-----QEGENTTLATGNT-LTLTNLSLSDTGTYTCT 426

Query: 283 ATN 285
             N
Sbjct: 427 GYN 435
>35419
          Length = 623

 Score = 32.7 bits (73), Expect = 0.53,   Method: Compositional matrix adjust.
 Identities = 24/90 (26%), Positives = 40/90 (44%), Gaps = 5/90 (5%)
 Frame = -2

Query: 30  VELSVGESKFFTCTAIGEPE-----SIDWYNPQGEKIISTQRVMLQKEGVRSRLTIYNAN 84
           +E++ G    FTC+   +PE      I W     E  IST    +      + LTI    
Sbjct: 547 LEVNAGTDAKFTCSGTTDPEEVHMLKIKWMKDNKE--ISTVEQRMTTNIQDNSLTISGTI 374

Query: 85  IEDAGIYRCQATDAKGQTQEATVVLEIYQK 114
           + D+G Y C +T+    + EA+ +L +  +
Sbjct: 373 VRDSGTYTCISTNGL-DSAEASAMLTVKDR 287
>34811
          Length = 613

 Score = 32.0 bits (71), Expect = 0.80,   Method: Compositional matrix adjust.
 Identities = 11/27 (40%), Positives = 16/27 (59%)
 Frame = +3

Query: 221 TAERGEEMTLTCKASGSPDPTISWFRN 247
           T    + +TLTC+  G P P I WF++
Sbjct: 510 TISNTQPLTLTCRGQGRPQPIIEWFKD 590
>20244
          Length = 452

 Score = 25.8 bits (55), Expect(2) = 0.81,   Method: Composition-based stats.
 Identities = 18/60 (30%), Positives = 30/60 (50%), Gaps = 4/60 (6%)
 Frame = -2

Query: 279 YVCK-ATNKAGED-QKQAFLQVFVQPH-ILQLKNETTSENGH-VTLVCEAEGEPVPEITW 334
           Y+C  A+N  GE  +++  LQV V    ++ L  + +   G  +   C  +G P P +TW
Sbjct: 241 YLCLLASNGLGEPVRREVELQVTVNAEAVIGLDPQNSYTPGSTIAFNCSVQGYPTPNVTW 62

 Score = 24.6 bits (52), Expect(2) = 0.81,   Method: Composition-based stats.
 Identities = 8/15 (53%), Positives = 11/15 (73%)
 Frame = -1

Query: 230 LTCKASGSPDPTISW 244
           L C A+G+P P I+W
Sbjct: 383 LRCFATGNPAPNITW 339
>27008
          Length = 771

 Score = 30.0 bits (66), Expect = 3.8,   Method: Compositional matrix adjust.
 Identities = 22/68 (32%), Positives = 31/68 (45%), Gaps = 4/68 (5%)
 Frame = +2

Query: 225 GEEMTLTC---KASGSPDPTISWF-RNGKLIEENEKYILKGSNTELTVRNIINKDGGSYV 280
           GE++ L C   K S   D T  +F RNG  I  N   IL   +  L   + +  D G++V
Sbjct: 446 GEDLILFCNLTKLSLLEDSTYLYFTRNGVTIPANHVTILTTRSVRLRYPHQVAADEGNFV 625

Query: 281 CKATNKAG 288
           C    + G
Sbjct: 626 CWLRQERG 649
>22019
          Length = 314

 Score = 29.6 bits (65), Expect = 4.3,   Method: Composition-based stats.
 Identities = 14/35 (40%), Positives = 22/35 (62%)
 Frame = +3

Query: 266 LTVRNIINKDGGSYVCKATNKAGEDQKQAFLQVFV 300
           L ++++ N+D G YVC+ +N  G  Q  A LQ+ V
Sbjct: 45  LLLQDVTNEDAGLYVCELSNMVG--QASAVLQLLV 143
>39864
          Length = 322

 Score = 29.3 bits (64), Expect = 6.4,   Method: Composition-based stats.
 Identities = 18/70 (25%), Positives = 32/70 (45%), Gaps = 3/70 (4%)
 Frame = +2

Query: 415 GNPINISC-DVTANPPASIHWRREKLLLPAKNTTHLKTHSVGRKM--ILEIAPTSDNDFG 471
           G  +N++C   ++NP A + W +    +   N   +   + G+    +L   PTS +   
Sbjct: 62  GQGMNLTCVTSSSNPAAEVTWLKGGQRIQGVNRGVVDGPNGGKNTTNVLHFIPTSSDHNA 241

Query: 472 RYNCTATNRI 481
            Y C ATN +
Sbjct: 242 MYGCRATNTL 271
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|166063992|ref|NP_766132.2| neurexin III [Mus
musculus]
         (1100 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

18680                                                                  58   2e-08
06395                                                                  50   6e-06
32228                                                                  47   3e-05
13401                                                                  40   0.004
29854                                                                  35   0.16 
26900                                                                  32   1.1  
30893                                                                  32   1.5  
33353                                                                  32   2.0  
14158                                                                  32   2.0  
04206                                                                  30   4.1  
12576                                                                  30   4.1  
>18680
          Length = 451

 Score = 58.2 bits (139), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 47/154 (30%), Positives = 72/154 (46%), Gaps = 9/154 (5%)
 Frame = -3

Query: 689 CQEDSCANQGVCMQQWEGFTCDCSMTSYSGNQCNDPGATYIFGKSGGLILYTWPANDRPS 748
           C  + C N G C + +  +TCDCS T + G  C       +  K   +I Y +      S
Sbjct: 446 CASNPCFNGGTCREGYSRYTCDCSYTPWRGWNCGREVGVNL--KQNYMIQYEFTEQQGLS 273

Query: 749 TRSDRLA-VGFSTTVKDGILVRIDSAPGLGDFLQLHI-EQGKIGVVFNIGTVDISIKEER 806
               + A +GFST VK GIL+++ S     D++ + +   G + VVF++G      +E  
Sbjct: 272 ATDFQYATIGFSTKVKQGILMQMKSVT-TSDYISVEMNNNGGVKVVFDVG---FQREEVN 105

Query: 807 TPVNDGKY-----HVVRFTRN--GGNATLQVDNW 833
           TP  D  +     HVV   R+  G    +QVDN+
Sbjct: 104 TPEIDVDFANTQVHVVTIRRSNKGRRVVVQVDNY 3

 Score = 50.4 bits (119), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 38/153 (24%), Positives = 71/153 (46%), Gaps = 3/153 (1%)
 Frame = -3

Query: 273 QCDSYPCKNNAVCKDGWNRFICDCTGTGYWGRTCEREASILSYDGSM--YMKVIMPMVMH 330
           +C S PC N   C++G++R+ CDC+ T + G  C RE  +      M  Y       +  
Sbjct: 449 KCASNPCFNGGTCREGYSRYTCDCSYTPWRGWNCGREVGVNLKQNYMIQYEFTEQQGLSA 270

Query: 331 TEAEDVSFRFMSQRAYGLLVATTSRDSADTLRLEL-DGGRVKLMVNLDCIRINCNSSKGP 389
           T+ +  +  F ++   G+L+   S  ++D + +E+ + G VK++ ++   R   N+   P
Sbjct: 269 TDFQYATIGFSTKVKQGILMQMKSVTTSDYISVEMNNNGGVKVVFDVGFQREEVNT---P 99

Query: 390 ETLYAGQKLNDNEWHTVRVVRRGKSLKLTVDDD 422
           E         + + H V + R  K  ++ V  D
Sbjct: 98  EI---DVDFANTQVHVVTIRRSNKGRRVVVQVD 9
>06395
          Length = 914

 Score = 49.7 bits (117), Expect = 6e-06,   Method: Compositional matrix adjust.
 Identities = 33/128 (25%), Positives = 63/128 (49%), Gaps = 9/128 (7%)
 Frame = -2

Query: 307 EREASILSYDGSMYMKV----IMP-MVMHTEAEDVSFRFMSQRAYGLLVATTSRDSADTL 361
            R  +I+  DGS Y+K     + P  ++ T+ E+ SF F++ +  GL+      +    L
Sbjct: 673 RRTTTIIRLDGSSYVKFDFSRLPPDTLVRTQEEEFSFYFLTNKPEGLIWY--HEEPRRNL 500

Query: 362 RLELDGGRVKLMVNLDCIRINCNSSKGPETLY----AGQKLNDNEWHTVRVVRRGKSLKL 417
            L +  G +        + +N + S  PE +     +G++ +D  WH +++ R G+ ++L
Sbjct: 499 YLAMKDGHL--------VFVNDDKSGTPEQVIIGERSGKRFDDYRWHKLKIRRNGRRIRL 344

Query: 418 TVDDDVAE 425
           TVDD   +
Sbjct: 343 TVDDKYPQ 320
>32228
          Length = 1295

 Score = 47.4 bits (111), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 49/227 (21%), Positives = 98/227 (43%), Gaps = 11/227 (4%)
 Frame = -3

Query: 508 YLTLATLQAYTSMHLFF---QFKTTSADGF---ILFNSGDGNDFIAVELVKGYIHYVFDL 561
           YLT ++    T  + ++    F+T   +G    I+ N+G     + ++LV+G++ Y F+ 
Sbjct: 912 YLTFSSTSQNTVHYPWYNGISFRTRXKEGTLMQIILNTG----HVTIQLVRGFVQYTFE- 748

Query: 562 GNGPNVIKGNSDRPLNDNQWHNVVITRDSSNTHSL----KVDTKV-VTQVINGAKNLDLK 616
               +        P++D  WH +    +    + L    +++  + +TQ ++G+   D++
Sbjct: 747 ----DSTVTLDAVPVSDGHWHYIEARWNHGRLNLLLDYGQIEKSITLTQSVSGS---DIQ 589

Query: 617 GDLYMAGLAQGMYSNLPKLVASRDGFQGCLASVDLNGRLPDLINDALHRSGQIERGCEVA 676
             +Y+ G  QG   N P      DGF GC+  + +   +  L+N+ +  +  + +GC   
Sbjct: 588 -RIYVGGYRQG---NEPI----SDGFSGCVKDIRVGNNMNALLNNPVETN--VGQGCSAP 439

Query: 677 LTKADLQGPSTTCQEDSCANQGVCMQQWEGFTCDCSMTSYSGNQCND 723
                       C+ + C   G C+ +W    C C      G +C D
Sbjct: 438 ----------NACEPNPCG-PGTCVDEWGHHRCLCP-PGMIGPKCED 334

 Score = 44.3 bits (103), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 39/154 (25%), Positives = 57/154 (37%), Gaps = 9/154 (5%)
 Frame = -3

Query: 687  TTCQEDSCANQGVCMQQWEGFTC---------DCSMTSYSGNQCNDPGATYIFGKSGGLI 737
            T CQ   C   G C + W  FTC         DCS    S  Q +  G       S   +
Sbjct: 1056 THCQSSPCTLGGKCKEGWNTFTCDCPEKTGGKDCSQVIESSRQLSGNGYLTFSSTSQNTV 877

Query: 738  LYTWPANDRPSTRSDRLAVGFSTTVKDGILVRIDSAPGLGDFLQLHIEQGKIGVVFNIGT 797
             Y W              + F T  K+G L++I    G    + + + +G +   F   T
Sbjct: 876  HYPW-----------YNGISFRTRXKEGTLMQIILNTG---HVTIQLVRGFVQYTFEDST 739

Query: 798  VDISIKEERTPVNDGKYHVVRFTRNGGNATLQVD 831
            V +    +  PV+DG +H +    N G   L +D
Sbjct: 738  VTL----DAVPVSDGHWHYIEARWNHGRLNLLLD 649

 Score = 36.6 bits (83), Expect = 0.051,   Method: Compositional matrix adjust.
 Identities = 13/24 (54%), Positives = 14/24 (58%)
 Frame = -3

Query: 273  QCDSYPCKNNAVCKDGWNRFICDC 296
             C S PC     CK+GWN F CDC
Sbjct: 1053 HCQSSPCTLGGKCKEGWNTFTCDC 982
>13401
          Length = 497

 Score = 40.4 bits (93), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 23/57 (40%), Positives = 27/57 (47%)
 Frame = -3

Query: 250 IRQLAEMQNAAGVKSSCSRMSAKQCDSYPCKNNAVCKDGWNRFICDCTGTGYWGRTC 306
           IRQ        G +    +    +C S PCKN   C  G N+F C CT TGY G TC
Sbjct: 171 IRQYFCNCTGTGYEGEFCQTDTDECASSPCKNGGNCSQGNNKFQCTCTDTGYRGDTC 1

 Score = 35.0 bits (79), Expect = 0.19,   Method: Compositional matrix adjust.
 Identities = 16/37 (43%), Positives = 22/37 (59%)
 Frame = -3

Query: 272 KQCDSYPCKNNAVCKDGWNRFICDCTGTGYWGRTCER 308
            +CD+ PC N   C+D  + F C C+GTG+ G  CE 
Sbjct: 339 NECDTKPCFNAGRCQDTVSGFTCHCSGTGFQGNRCEE 229

 Score = 34.7 bits (78), Expect = 0.20,   Method: Compositional matrix adjust.
 Identities = 16/36 (44%), Positives = 24/36 (66%)
 Frame = -3

Query: 274 CDSYPCKNNAVCKDGWNRFICDCTGTGYWGRTCERE 309
           C ++ C+N A C DG  ++ C+CTGTGY G  C+ +
Sbjct: 216 CVNHRCENGAPCVDGIRQYFCNCTGTGYEGEFCQTD 109

 Score = 30.4 bits (67), Expect = 4.6,   Method: Compositional matrix adjust.
 Identities = 15/33 (45%), Positives = 17/33 (51%)
 Frame = -3

Query: 689 CQEDSCANQGVCMQQWEGFTCDCSMTSYSGNQC 721
           C    C N G C     GFTC CS T + GN+C
Sbjct: 333 CDTKPCFNAGRCQDTVSGFTCHCSGTGFQGNRC 235
>29854
          Length = 417

 Score = 35.0 bits (79), Expect = 0.16,   Method: Compositional matrix adjust.
 Identities = 14/30 (46%), Positives = 15/30 (50%)
 Frame = -1

Query: 285 CKDGWNRFICDCTGTGYWGRTCEREASILS 314
           C   WN F CDC  TGY G  C   A  +S
Sbjct: 414 CTQSWNTFDCDCQNTGYKGEMCHISAHHIS 325

 Score = 32.0 bits (71), Expect = 1.4,   Method: Compositional matrix adjust.
 Identities = 11/23 (47%), Positives = 12/23 (52%)
 Frame = -1

Query: 700 CMQQWEGFTCDCSMTSYSGNQCN 722
           C Q W  F CDC  T Y G  C+
Sbjct: 414 CTQSWNTFDCDCQNTGYKGEMCH 346
>26900
          Length = 871

 Score = 32.3 bits (72), Expect = 1.1,   Method: Composition-based stats.
 Identities = 13/29 (44%), Positives = 19/29 (65%)
 Frame = +2

Query: 108 NGLILFTHGKPQERKDVRSQKNTKVDFFA 136
           N   LF   K + R+DV ++ N+K+DFFA
Sbjct: 230 NAWCLFYSSKLKTRRDVSAKTNSKIDFFA 316
>30893
          Length = 490

 Score = 32.0 bits (71), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 21/65 (32%), Positives = 27/65 (41%)
 Frame = +2

Query: 245 GRSKNIRQLAEMQNAAGVKSSCSRMSAKQCDSYPCKNNAVCKDGWNRFICDCTGTGYWGR 304
           G   N         A+G + S       +C S PC+N A C D   R+ C C   GY G 
Sbjct: 119 GTCHNTGNTHMCTCASGFEGSYCENDINECFSAPCQNGATCTDLIGRYTCTCE-PGYQGL 295

Query: 305 TCERE 309
            CE +
Sbjct: 296 NCEYD 310
>33353
          Length = 559

 Score = 31.6 bits (70), Expect = 2.0,   Method: Compositional matrix adjust.
 Identities = 13/35 (37%), Positives = 16/35 (45%)
 Frame = -2

Query: 274 CDSYPCKNNAVCKDGWNRFICDCTGTGYWGRTCER 308
           C   PC+N   C  G   + C C   GY G  CE+
Sbjct: 531 CAENPCRNGGTCIPGIGTYTCQCR-QGYLGVHCEQ 430
>14158
          Length = 668

 Score = 31.6 bits (70), Expect = 2.0,   Method: Compositional matrix adjust.
 Identities = 16/44 (36%), Positives = 24/44 (54%), Gaps = 3/44 (6%)
 Frame = +3

Query: 682 LQGPSTTCQEDSCANQGVCMQQWE---GFTCDCSMTSYSGNQCN 722
            + P   C  +SCAN   C    +   G+ CDC+ ++YSG+ CN
Sbjct: 69  CETPYNACDNNSCANNSTCTVNPDVSRGYVCDCADSNYSGDLCN 200
>04206
          Length = 778

 Score = 30.4 bits (67), Expect = 4.1,   Method: Compositional matrix adjust.
 Identities = 25/94 (26%), Positives = 41/94 (43%)
 Frame = +1

Query: 398 LNDNEWHTVRVVRRGKSLKLTVDDDVAEGTMVGDHTRLEFHNIETGIMTEKRYISVVPSS 457
           L  NE+    VV +G+  K+         +  G H   + H +   I T K+Y  + PS+
Sbjct: 169 LRKNEF----VVIKGRPCKIVE----MSTSKTGKHGHAKVHLVALDIFTGKKYEDICPST 324

Query: 458 FIGHLQSLMFNGLLYIDLCKNGDIDYCELKARFG 491
              ++ ++    LLY+D+    D DY  L    G
Sbjct: 325 HNMNVPNVTRTDLLYVDV---SDEDYLSLMTDSG 417
>12576
          Length = 1682

 Score = 30.4 bits (67), Expect = 4.1,   Method: Compositional matrix adjust.
 Identities = 24/76 (31%), Positives = 32/76 (42%), Gaps = 8/76 (10%)
 Frame = -1

Query: 245 GRSKNIRQ----LAEMQNAAGVKSSCSRMSAKQCDSYPCKNNAVCKDGWNR----FICDC 296
           G  KN+ Q    +A    A G   +        C S PCKN A C     R    F C C
Sbjct: 914 GMCKNVVQNGALVAACVCAPGFTGATCSQENNPCSSRPCKNGATCSPQLTRSSATFKCXC 735

Query: 297 TGTGYWGRTCEREASI 312
             +GY G TC+++  +
Sbjct: 734 K-SGYSGETCDQKVDL 690

 Score = 30.4 bits (67), Expect = 4.5,   Method: Compositional matrix adjust.
 Identities = 21/68 (30%), Positives = 25/68 (36%), Gaps = 17/68 (25%)
 Frame = -2

Query: 685  PSTTCQEDSCANQGVCMQQWEGFTCDC-----------------SMTSYSGNQCNDPGAT 727
            P T C  + C N G C      FTC C                 S    +G +CN  GA+
Sbjct: 1672 PITACDSNPCQNGGQCQPNGGSFTCSCVNGFSGVNCASRPNPCGSNPCANGGRCNANGAS 1493

Query: 728  YIFGKSGG 735
            Y    SGG
Sbjct: 1492 YTCSCSGG 1469

 Score = 29.6 bits (65), Expect = 7.3,   Method: Compositional matrix adjust.
 Identities = 16/42 (38%), Positives = 22/42 (52%)
 Frame = -2

Query: 265  SCSRMSAKQCDSYPCKNNAVCKDGWNRFICDCTGTGYWGRTC 306
            SC+ ++A  CDS PC+N   C+     F C C   G+ G  C
Sbjct: 1681 SCTPITA--CDSNPCQNGGQCQPNGGSFTCSCV-NGFSGVNC 1565

 Score = 29.3 bits (64), Expect = 9.8,   Method: Compositional matrix adjust.
 Identities = 13/34 (38%), Positives = 17/34 (50%)
 Frame = -2

Query: 274  CDSYPCKNNAVCKDGWNRFICDCTGTGYWGRTCE 307
            C S PC N   C      + C C+G GY+G  C+
Sbjct: 1546 CGSNPCANGGRCNANGASYTCSCSG-GYYGFNCQ 1448
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|22122663|ref|NP_666254.1| tudor domain containing 7
[Mus musculus]
         (1086 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

02407                                                                  58   2e-08
06128                                                                  50   5e-06
04982                                                                  49   1e-05
03574                                                                  46   1e-04
21795                                                                  45   1e-04
34863                                                                  41   0.003
17475                                                                  40   0.007
29083                                                                  34   0.33 
17718                                                                  30   4.5  
19977                                                                  30   4.7  
>02407
          Length = 2662

 Score = 58.2 bits (139), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 51/176 (28%), Positives = 77/176 (43%), Gaps = 7/176 (3%)
 Frame = -2

Query: 641  YTNVKVTNICSDGTLYCQVPCKG--LNKLNDLLHKTEDYFHCKHMTSEYFISLPFCGKIC 698
            YT V +T +  D T Y Q    G  + +L + + +  D      +   Y    P  G +C
Sbjct: 2658 YTKVIITEVTDDFTFYAQKVDNGPQVERLMEQMRQEMD--SNPPLPGAY---TPKRGDLC 2494

Query: 699  L--FHCKGKWLRVEITNVHSSRALDVQFLDSGNSTSVKVSELREIPPRFLQEMLAIPPQA 756
               F    +W R ++  VHS +A D+ F+D GN  SV    L  +P  F    L+ PPQA
Sbjct: 2493 AAKFSADDQWYRAKVQKVHSGKA-DILFIDFGNKESVASGSLAALPAAF----LSTPPQA 2329

Query: 757  IKCCLADL---PQSIGMWTPDAVLWLRDSVLNCSDCSIKVTKMDETKGVAYVYLFT 809
             +  LA +   P  +     DAV  L   ++N     ++V     + GV YV + T
Sbjct: 2328 NEYSLAGVALPPDVVEDGKQDAVDALYRDIMN---HQVQVNVEYRSGGVDYVTMMT 2170

 Score = 40.0 bits (92), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 29/104 (27%), Positives = 49/104 (47%), Gaps = 1/104 (0%)
 Frame = -2

Query: 479  QELMEDEMKEFYSKNPRVTPIQTVHVGQLLAVN-AEEDAWLRAQIISTDENKIKVCYVDY 537
            + LME +M++    NP +    T   G L A   + +D W RA++      K  + ++D+
Sbjct: 2580 ERLME-QMRQEMDSNPPLPGAYTPKRGDLCAAKFSADDQWYRAKVQKVHSGKADILFIDF 2404

Query: 538  GFCENIEKSKAYRLNPRFCSLSFQATKCKLAGLEVLNDDPDLVK 581
            G  E++       L   F S   QA +  LAG+ +    PD+V+
Sbjct: 2403 GNKESVASGSLAALPAAFLSTPPQANEYSLAGVAL---PPDVVE 2281
>06128
          Length = 1202

 Score = 50.1 bits (118), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 38/127 (29%), Positives = 57/127 (44%), Gaps = 4/127 (3%)
 Frame = +3

Query: 641 YTNVKVTNICSDGTLYCQVPCKG--LNKLNDLLHKTEDYFHCKHMTSEYFISLPFCGKIC 698
           YT V +T +  D T Y Q    G  + +L + + +  D      +   Y    P  G +C
Sbjct: 786 YTKVIITEVTDDFTFYAQKVDNGPQVERLMEQMRQEMD--SNPPLPGAY---TPKRGDLC 950

Query: 699 L--FHCKGKWLRVEITNVHSSRALDVQFLDSGNSTSVKVSELREIPPRFLQEMLAIPPQA 756
              F    +W R ++  VHS +A D+ F+D GN  SV    L  +P  F    L+ PPQA
Sbjct: 951 AAKFSADDQWYRAKVQKVHSGKA-DILFIDFGNKESVASGSLAALPAAF----LSTPPQA 1115

Query: 757 IKCCLAD 763
            +  L +
Sbjct: 1116NEYVLVE 1136

 Score = 34.3 bits (77), Expect = 0.31,   Method: Compositional matrix adjust.
 Identities = 26/111 (23%), Positives = 47/111 (42%), Gaps = 1/111 (0%)
 Frame = +3

Query: 455 VLVVELSNTNDVVIRYVGKDYSAAQELMEDEMKEFYSKNPRVTPIQTVHVGQLLAVN-AE 513
           V++ E+  T+D        D     E + ++M++    NP +    T   G L A   + 
Sbjct: 795 VIITEV--TDDFTFYAQKVDNGPQVERLMEQMRQEMDSNPPLPGAYTPKRGDLCAAKFSA 968

Query: 514 EDAWLRAQIISTDENKIKVCYVDYGFCENIEKSKAYRLNPRFCSLSFQATK 564
           +D W RA++      K  + ++D+G  E++       L   F S   QA +
Sbjct: 969 DDQWYRAKVQKVHSGKADILFIDFGNKESVASGSLAALPAAFLSTPPQANE 1121
>04982
          Length = 1215

 Score = 48.5 bits (114), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 30/95 (31%), Positives = 50/95 (52%), Gaps = 6/95 (6%)
 Frame = +1

Query: 482 MEDEMKEFYSKNP------RVTPIQTVHVGQLLAVNAEEDAWLRAQIISTDENKIKVCYV 535
           M D+M  FYS NP      R+T ++   V  + A  AE++ W RA+++  ++ K+ + Y 
Sbjct: 331 MTDDMSLFYS-NPDTAQTYRLTEVKEGDV--VAAAFAEDNMWYRARVVGFEDGKVDLYYF 501

Query: 536 DYGFCENIEKSKAYRLNPRFCSLSFQATKCKLAGL 570
           D+G    + +     L   + SL  QA +CKLA +
Sbjct: 502 DFGDNGLVPEEALRELKAEYLSLPVQAIECKLANV 606
>03574
          Length = 3150

 Score = 45.8 bits (107), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 24/71 (33%), Positives = 41/71 (57%), Gaps = 1/71 (1%)
 Frame = -3

Query: 502  VHVGQL-LAVNAEEDAWLRAQIISTDENKIKVCYVDYGFCENIEKSKAYRLNPRFCSLSF 560
            V VGQ+ LA  + ++AW RA+++   +  +KV YVD+G    ++ S   R++P+ C    
Sbjct: 1462 VKVGQICLAHFSIDNAWYRARVLEVTQKDVKVKYVDFGNSSRVDTSLVRRISPQLCDKPQ 1283

Query: 561  QATKCKLAGLE 571
             A + KL  L+
Sbjct: 1282 IAYEFKLHNLK 1250
>21795
          Length = 605

 Score = 45.4 bits (106), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 31/103 (30%), Positives = 56/103 (54%), Gaps = 9/103 (8%)
 Frame = +3

Query: 948  ERDQVYAAKVENKWYR-VLLKGILTNGLVS-VYELDYGKHELVNIRKVQPLVDVFRKLPF 1005
            E +  Y A++E+   R +LL+GI T   V+ V+ +DYG  + + + +++ L      +  
Sbjct: 291  EYEAYYRARIESLQTRTLLLRGIPTTTRVAQVFFVDYGNRDEIPLDRLRALPSEAFSISM 470

Query: 1006 QAVTAQL-----AGVKC--SQWSEEASMVFRNHVEKKALVALV 1041
            QA+  +L     + VKC    W++EA+ VFR  V+  + +A V
Sbjct: 471  QAIECELTEIRPSSVKCPDGNWTKEANTVFRKMVQDHSFLAQV 599
>34863
          Length = 634

 Score = 40.8 bits (94), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 21/59 (35%), Positives = 32/59 (54%), Gaps = 1/59 (1%)
 Frame = -3

Query: 958  ENKWYRVLLKGILTNGLV-SVYELDYGKHELVNIRKVQPLVDVFRKLPFQAVTAQLAGV 1015
            +N WYR  ++ +  +G   S++  DYG  E   I  +  +   FR LP QA+  QLAG+
Sbjct: 239  DNLWYRGRVERVYEDGTTCSIFFTDYGNKEDKEISSLMVVPQQFRALPAQAIACQLAGL 63

 Score = 39.3 bits (90), Expect = 0.010,   Method: Compositional matrix adjust.
 Identities = 22/64 (34%), Positives = 32/64 (50%), Gaps = 1/64 (1%)
 Frame = -3

Query: 706 WLRVEITNVHS-SRALDVQFLDSGNSTSVKVSELREIPPRFLQEMLAIPPQAIKCCLADL 764
           W R  +  V+       + F D GN    ++S L  +P    Q+  A+P QAI C LA L
Sbjct: 230 WYRGRVERVYEDGTTCSIFFTDYGNKEDKEISSLMVVP----QQFRALPAQAIACQLAGL 63

Query: 765 PQSI 768
           P+S+
Sbjct: 62  PESV 51

 Score = 37.4 bits (85), Expect = 0.034,   Method: Compositional matrix adjust.
 Identities = 24/74 (32%), Positives = 39/74 (52%), Gaps = 3/74 (4%)
 Frame = -3

Query: 500 QTVHVGQLLAVN-AEEDAWLRAQI--ISTDENKIKVCYVDYGFCENIEKSKAYRLNPRFC 556
           QTV  G ++ V  +E++ W R ++  +  D     + + DYG  E+ E S    +  +F 
Sbjct: 284 QTVSPGDVVLVEFSEDNLWYRGRVERVYEDGTTCSIFFTDYGNKEDKEISSLMVVPQQFR 105

Query: 557 SLSFQATKCKLAGL 570
           +L  QA  C+LAGL
Sbjct: 104 ALPAQAIACQLAGL 63
>17475
          Length = 884

 Score = 39.7 bits (91), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 23/84 (27%), Positives = 40/84 (47%), Gaps = 1/84 (1%)
 Frame = -3

Query: 703 KGKWLRVEITNVHSSRALDVQFLDSGNSTSVKVSELREIPPRFLQEMLAIPPQAIKCCLA 762
           +G+W R E+T + SS+ + V F D GN   + +S+L  +P        + P   +KCC+ 
Sbjct: 564 QGEWFRSEVTEIVSSQ-VHVTFFDYGNEAVLDLSDLCPLPKELCH---SFPLATVKCCID 397

Query: 763 DL-PQSIGMWTPDAVLWLRDSVLN 785
            + P     W  + +   R  + N
Sbjct: 396 GIGPAGGDTWDEECISVTRSLLEN 325
>29083
          Length = 710

 Score = 33.9 bits (76), Expect = 0.33,   Method: Composition-based stats.
 Identities = 12/35 (34%), Positives = 25/35 (71%), Gaps = 3/35 (8%)
 Frame = -1

Query: 512 AEEDAWLRAQI---ISTDENKIKVCYVDYGFCENI 543
           +E+  W R Q+   I+ +++K+K+ Y+D+G CE++
Sbjct: 128 SEDGEWYRCQLRMNIANNQDKVKIQYIDFGNCEDV 24
>17718
          Length = 637

 Score = 30.4 bits (67), Expect = 4.5,   Method: Composition-based stats.
 Identities = 19/84 (22%), Positives = 38/84 (45%)
 Frame = -3

Query: 456 LVVELSNTNDVVIRYVGKDYSAAQELMEDEMKEFYSKNPRVTPIQTVHVGQLLAVNAEED 515
           +VV   +     +R +GKDYS   E  ED +   Y+K    +  + +    +  V+ +  
Sbjct: 251 VVVAFVDLQHCWLRLIGKDYSERLEGFEDGLVSLYTKGQGESQSRRLQADTVCVVHCDL- 75

Query: 516 AWLRAQIISTDENKIKVCYVDYGF 539
            + R +I     N+    ++D+G+
Sbjct: 74  LYHRVKITEIVHNQANCFFLDHGY 3
>19977
          Length = 408

 Score = 30.0 bits (66), Expect = 4.7,   Method: Composition-based stats.
 Identities = 16/41 (39%), Positives = 22/41 (53%), Gaps = 8/41 (19%)
 Frame = +1

Query: 697 ICLFHCKGKWLRV--------EITNVHSSRALDVQFLDSGN 729
           +C   C G   RV        EI++VHS  + DVQFL+ G+
Sbjct: 34  VCS*ECGGTCCRVL*RRFFIGEISSVHSPTSADVQFLEKGS 156
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|25141233|ref|NP_034901.2| matrin 3 [Mus musculus]
         (846 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

02336                                                                  57   2e-08
07311                                                                  36   0.061
12506                                                                  35   0.19 
17681                                                                  30   4.8  
>02336
          Length = 1332

 Score = 57.4 bits (137), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 22/54 (40%), Positives = 34/54 (62%)
 Frame = -2

Query: 780 IGPYQPNVPVGIDYVIPKTGFYCKLCSLFYTNEEVAKNTHCSSLPHYQKLKKFL 833
           +  Y  +   G   V+P +G++CKLC+ FY NE  AK++HC +  HY K K+F+
Sbjct: 218 LARYDTDTSYGQMCVVPVSGWFCKLCNKFYNNESAAKDSHCKTEDHYVKYKRFV 57
>07311
          Length = 2662

 Score = 36.2 bits (82), Expect = 0.061,   Method: Compositional matrix adjust.
 Identities = 16/54 (29%), Positives = 29/54 (53%)
 Frame = -1

Query: 781 GPYQPNVPVGIDYVIPKTGFYCKLCSLFYTNEEVAKNTHCSSLPHYQKLKKFLN 834
           G  Q     G+++++P + FYC LC  F  +  +A+ TH  S  H+ +   +L+
Sbjct: 322 GQVQAAPIKGLEFMMPTSAFYCSLCKEFCGDLSIAE-THMKSEEHHLQYTDYLS 164
>12506
          Length = 1056

 Score = 34.7 bits (78), Expect = 0.19,   Method: Compositional matrix adjust.
 Identities = 26/79 (32%), Positives = 41/79 (51%), Gaps = 7/79 (8%)
 Frame = -3

Query: 502  NLPHSGYSDSAVLKLA-EPYGKIKN------YILMRMKSQAFIEMETREDAMAMVDHCLK 554
            +L  +G  D  VL  A  P+G I +      Y   + +  AFIE E  EDA A +D+  +
Sbjct: 1051 SLFTAGEVDDKVLHAAFLPFGDIVDIQIPLDYETEKHRGFAFIEFELAEDAAAAIDNMNE 872

Query: 555  KALWFQGRCVKVDLSEKYK 573
              L+  GR ++V+L++  K
Sbjct: 871  SELF--GRTIRVNLAKPMK 821

 Score = 32.3 bits (72), Expect = 0.76,   Method: Compositional matrix adjust.
 Identities = 21/61 (34%), Positives = 33/61 (54%), Gaps = 6/61 (9%)
 Frame = -3

Query: 421 PFG-VISNHLILNKINE-----AFIEMATTEDAQAAVDYYTTTPALVFGKPVRVHLSQKY 474
           PFG ++   + L+   E     AFIE    EDA AA+D    +   +FG+ +RV+L++  
Sbjct: 997 PFGDIVDIQIPLDYETEKHRGFAFIEFELAEDAAAAIDNMNESE--LFGRTIRVNLAKPM 824

Query: 475 K 475
           K
Sbjct: 823 K 821
>17681
          Length = 964

 Score = 29.6 bits (65), Expect = 4.8,   Method: Compositional matrix adjust.
 Identities = 15/67 (22%), Positives = 32/67 (47%)
 Frame = +2

Query: 485 DQKFDQKQELGRVIHLSNLPHSGYSDSAVLKLAEPYGKIKNYILMRMKSQAFIEMETRED 544
           ++ ++Q       ++    P +  SD  + K    +G I++  + + K  AFI+  T+E 
Sbjct: 389 EEVYNQSSPTNTTVYCGGFPPNVISDELMHKHFMQFGPIQDVRVFKDKGFAFIKFVTKEA 568

Query: 545 AMAMVDH 551
           A   ++H
Sbjct: 569 AARAIEH 589
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6755478|ref|NP_035488.1| splicing factor,
arginine/serine-rich 2 [Mus musculus]
         (221 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

11579                                                                  55   2e-08
19868                                                                  47   5e-06
02415                                                                  47   6e-06
00302                                                                  47   8e-06
01278                                                                  46   1e-05
11126                                                                  46   1e-05
24983                                                                  46   1e-05
17681                                                                  44   4e-05
11019                                                                  44   6e-05
12506                                                                  40   6e-04
26197                                                                  39   0.001
12350                                                                  39   0.002
31618                                                                  39   0.002
03406                                                                  37   0.006
00817                                                                  37   0.007
30672                                                                  37   0.007
16016                                                                  37   0.007
31310                                                                  36   0.011
16427                                                                  36   0.012
05273                                                                  36   0.012
02140                                                                  36   0.016
01937                                                                  32   0.22 
08670                                                                  31   0.31 
23250                                                                  28   2.6  
>11579
          Length = 1307

 Score = 55.5 bits (132), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 26/46 (56%), Positives = 31/46 (67%)
 Frame = +3

Query: 54 SRGFAFVRFHDKRXXXXXXXXXXXXVLDGRELRVQMARYGRPPDSH 99
          SRGFAFVRF+D+R            +LDGRE+R QMARYGRP + H
Sbjct: 3  SRGFAFVRFYDRRDAEDAMDSMDGALLDGREVRCQMARYGRPAEPH 140
>19868
          Length = 434

 Score = 47.4 bits (111), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 20/47 (42%), Positives = 32/47 (68%)
 Frame = +2

Query: 18 VDNLTYRTSPDTLRRVFEKYGRVGDVYIPRDRYTKESRGFAFVRFHD 64
          V  L+++TSP++LR  F K+G + +V + +D  T+ SRGF F+ F D
Sbjct: 11 VGGLSWQTSPESLRDYFNKFGEITEVMVMKDPTTRRSRGFGFITFGD 151
>02415
          Length = 2763

 Score = 47.0 bits (110), Expect = 6e-06,   Method: Compositional matrix adjust.
 Identities = 27/83 (32%), Positives = 41/83 (49%)
 Frame = -1

Query: 14   TSLKVDNLTYRTSPDTLRRVFEKYGRVGDVYIPRDRYTKESRGFAFVRFHDKRXXXXXXX 73
            T + V  L Y T+  +LR  F+K+G + +  +  DR T +SRG+ FV   D R       
Sbjct: 1926 TKIFVGGLPYHTTDHSLREYFDKFGDIDEAVVITDRQTGKSRGYGFVTMAD-RTGADRAC 1750

Query: 74   XXXXXVLDGRELRVQMARYGRPP 96
                 ++DGR+  V +A  G  P
Sbjct: 1749 KDPNPIIDGRKANVNLAYIGAKP 1681
>00302
          Length = 927

 Score = 46.6 bits (109), Expect = 8e-06,   Method: Compositional matrix adjust.
 Identities = 26/76 (34%), Positives = 36/76 (47%)
 Frame = -1

Query: 15  SLKVDNLTYRTSPDTLRRVFEKYGRVGDVYIPRDRYTKESRGFAFVRFHDKRXXXXXXXX 74
            L +  L+  T    LR VF +YG + +V +  DR T  SRGFAFV F            
Sbjct: 462 CLGIFGLSLYTQERGLREVFGRYGHISEVQVVYDRQTGRSRGFAFVYFKSSEDAHEAKDR 283

Query: 75  XXXXVLDGRELRVQMA 90
                +DGR++RV  +
Sbjct: 282 CNGIEIDGRKIRVDFS 235
>01278
          Length = 1082

 Score = 45.8 bits (107), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 17/49 (34%), Positives = 32/49 (65%)
 Frame = +2

Query: 15  SLKVDNLTYRTSPDTLRRVFEKYGRVGDVYIPRDRYTKESRGFAFVRFH 63
           +++V NL+  T    L+ +F  +G +  +Y+ +D+ T +S+GFAF+ FH
Sbjct: 638 TIRVTNLSEDTRESDLQELFRPFGPISRIYLAKDKVTGQSKGFAFINFH 784
>11126
          Length = 1061

 Score = 45.8 bits (107), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 25/81 (30%), Positives = 38/81 (46%)
 Frame = -3

Query: 15  SLKVDNLTYRTSPDTLRRVFEKYGRVGDVYIPRDRYTKESRGFAFVRFHDKRXXXXXXXX 74
           S+ V N+ Y  + + L + F   G V  V I  D+Y+   +GFA+V F DK         
Sbjct: 627 SVYVGNVDYGATAEELEQHFHGCGSVNRVTILCDKYSGHPKGFAYVEFADKDSVVTAKCT 448

Query: 75  XXXXVLDGRELRVQMARYGRP 95
               +  GR+++V   R  RP
Sbjct: 447 GMDSLFRGRQIKVTPKRTNRP 385
>24983
          Length = 433

 Score = 45.8 bits (107), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 25/76 (32%), Positives = 38/76 (50%)
 Frame = -2

Query: 21  LTYRTSPDTLRRVFEKYGRVGDVYIPRDRYTKESRGFAFVRFHDKRXXXXXXXXXXXXVL 80
           L Y T+  +LR  F+K+G + +  +  DR T +SRG+ FV   D R            ++
Sbjct: 294 LPYHTTDHSLREYFDKFGDIDEAVVITDRQTGKSRGYGFVTMAD-RTGADRACKDPNPII 118

Query: 81  DGRELRVQMARYGRPP 96
           DGR+  V +A  G  P
Sbjct: 117 DGRKANVNLAYIGAKP 70
>17681
          Length = 964

 Score = 44.3 bits (103), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 24/91 (26%), Positives = 38/91 (41%)
 Frame = +2

Query: 6  PPPDVEGMTSLKVDNLTYRTSPDTLRRVFEKYGRVGDVYIPRDRYTKESRGFAFVRFHDK 65
          P  D+     + V +L+     +TLR  F  +G + +  I RD  T +S+G+AFV F  K
Sbjct: 8  PKTDISSHHHIFVGDLSPEIETETLREAFAPFGEISNCRIVRDPQTMKSKGYAFVSFVKK 187

Query: 66 RXXXXXXXXXXXXVLDGRELRVQMARYGRPP 96
                        +  R +R   +    PP
Sbjct: 188AEAENAIQAMNGQWIGSRSIRTNWSTRKLPP 280
>11019
          Length = 552

 Score = 43.9 bits (102), Expect = 6e-05,   Method: Compositional matrix adjust.
 Identities = 18/47 (38%), Positives = 31/47 (65%)
 Frame = -1

Query: 18  VDNLTYRTSPDTLRRVFEKYGRVGDVYIPRDRYTKESRGFAFVRFHD 64
           +  L+++T+ +TLR  FEK+G + +  + +D  +K SRGF FV + D
Sbjct: 552 IGGLSWQTTTETLRSYFEKFGEIKESMVMKDPTSKRSRGFGFVTYKD 412

 Score = 33.1 bits (74), Expect = 0.088,   Method: Compositional matrix adjust.
 Identities = 15/48 (31%), Positives = 27/48 (56%)
 Frame = -1

Query: 18  VDNLTYRTSPDTLRRVFEKYGRVGDVYIPRDRYTKESRGFAFVRFHDK 65
           V  L+  T+ + ++  F+ YG + +  +  D+ T   RGFAFV F ++
Sbjct: 222 VGGLSSSTTVEDIKNYFKAYGTIEEATLMFDKVTSRHRGFAFVTFDNE 79
>12506
          Length = 1056

 Score = 40.4 bits (93), Expect = 6e-04,   Method: Compositional matrix adjust.
 Identities = 20/62 (32%), Positives = 29/62 (46%)
 Frame = -3

Query: 30   LRRVFEKYGRVGDVYIPRDRYTKESRGFAFVRFHDKRXXXXXXXXXXXXVLDGRELRVQM 89
            L   F  +G + D+ IP D  T++ RGFAF+ F                 L GR +RV +
Sbjct: 1015 LHAAFLPFGDIVDIQIPLDYETEKHRGFAFIEFELAEDAAAAIDNMNESELFGRTIRVNL 836

Query: 90   AR 91
            A+
Sbjct: 835  AK 830
>26197
          Length = 1365

 Score = 39.3 bits (90), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 19/47 (40%), Positives = 26/47 (55%)
 Frame = -2

Query: 18   VDNLTYRTSPDTLRRVFEKYGRVGDVYIPRDRYTKESRGFAFVRFHD 64
            V  L++ TS   LR  FEK+G V    +  D  + +SRGF FV F +
Sbjct: 1286 VGGLSWETSSKHLREYFEKFGEVTSCTLKTDLDSGKSRGFGFVVFKE 1146
>12350
          Length = 975

 Score = 38.9 bits (89), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 17/50 (34%), Positives = 30/50 (60%)
 Frame = -2

Query: 13  MTSLKVDNLTYRTSPDTLRRVFEKYGRVGDVYIPRDRYTKESRGFAFVRF 62
            + L V  L ++++ D LR  F ++G +  V + +D  T +S+GF F+RF
Sbjct: 623 CSDLIVLGLPWKSTEDDLRSYFSQFGDLLMVQVKKDPKTGQSKGFGFIRF 474

 Score = 37.4 bits (85), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 26/65 (40%), Positives = 30/65 (46%), Gaps = 5/65 (7%)
 Frame = -2

Query: 5   RPPPDVEGMTSLK-----VDNLTYRTSPDTLRRVFEKYGRVGDVYIPRDRYTKESRGFAF 59
           R P   EG   L      V   T   + D LR+ F K+G V DV+IPR       R FAF
Sbjct: 404 RIPNSKEGAQQLMNRKIFVGRCTDDMTADDLRQFFSKFGEVVDVFIPR-----PFRAFAF 240

Query: 60  VRFHD 64
           V F D
Sbjct: 239 VSFAD 225
>31618
          Length = 716

 Score = 38.9 bits (89), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 19/49 (38%), Positives = 27/49 (55%)
 Frame = +1

Query: 16  LKVDNLTYRTSPDTLRRVFEKYGRVGDVYIPRDRYTKESRGFAFVRFHD 64
           L V  L++ T+   LR  F KYG +  + +  D  T  SRGFAF+ F +
Sbjct: 298 LFVGGLSWETTEKELRDHFGKYGEIESINVKTDPQTGRSRGFAFIVFTN 444
>03406
          Length = 1292

 Score = 37.0 bits (84), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 18/47 (38%), Positives = 25/47 (53%)
 Frame = +3

Query: 18  VDNLTYRTSPDTLRRVFEKYGRVGDVYIPRDRYTKESRGFAFVRFHD 64
           V  L++ T    LR  FEK+G V    +  D  + +SRGF FV F +
Sbjct: 252 VGGLSWETXSKHLREYFEKFGEVTSCTLKTDLDSGKSRGFGFVVFKE 392
>00817
          Length = 2606

 Score = 37.0 bits (84), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 22/76 (28%), Positives = 35/76 (46%)
 Frame = -2

Query: 25   TSPDTLRRVFEKYGRVGDVYIPRDRYTKESRGFAFVRFHDKRXXXXXXXXXXXXVLDGRE 84
            T   +LR  FEKYG + +  + +D  TK SR F+F+ F +               +DGR 
Sbjct: 2518 TDESSLRSYFEKYGDIRECIVVKDPATKRSRCFSFITFGNA-ENVDEVQKDRPHTIDGRT 2342

Query: 85   LRVQMARYGRPPDSHH 100
            +  + A      ++HH
Sbjct: 2341 VETKRAMPREDTENHH 2294
>30672
          Length = 877

 Score = 37.0 bits (84), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 19/60 (31%), Positives = 33/60 (55%)
 Frame = +3

Query: 5   RPPPDVEGMTSLKVDNLTYRTSPDTLRRVFEKYGRVGDVYIPRDRYTKESRGFAFVRFHD 64
           +P  ++     L + NL ++     +R  F K+G + +V IP  +  + SRGFAFV+F +
Sbjct: 378 QPKQELGKRCRLIIRNLAFKCKEADIRSHFGKFGTISEVTIPLKQGDR-SRGFAFVQFTE 554
>16016
          Length = 1364

 Score = 36.6 bits (83), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 22/76 (28%), Positives = 35/76 (46%)
 Frame = -2

Query: 25   TSPDTLRRVFEKYGRVGDVYIPRDRYTKESRGFAFVRFHDKRXXXXXXXXXXXXVLDGRE 84
            T   +LR  FEKYG + +  + +D  TK SR F+F+ F +               +DGR 
Sbjct: 1276 TDESSLRSYFEKYGDIRECIVVKDPATKRSRCFSFITFGNAE-NVDEVQKDRPHTIDGRT 1100

Query: 85   LRVQMARYGRPPDSHH 100
            +  + A      ++HH
Sbjct: 1099 VETKRAMPREDTENHH 1052
>31310
          Length = 469

 Score = 36.2 bits (82), Expect = 0.011,   Method: Compositional matrix adjust.
 Identities = 18/85 (21%), Positives = 38/85 (44%)
 Frame = -3

Query: 13  MTSLKVDNLTYRTSPDTLRRVFEKYGRVGDVYIPRDRYTKESRGFAFVRFHDKRXXXXXX 72
           M  + V ++ +    DT+++ F  +G +  V +  D  T + +GF+F+ +          
Sbjct: 326 MCRIYVGSINFEIREDTIKQAFLPFGPIKSVNLSWDPITNKHKGFSFIEYDVPEAAQLAL 147

Query: 73  XXXXXXVLDGRELRVQMARYGRPPD 97
                 ++ GR ++V     GRP +
Sbjct: 146 EQMNGVMIGGRNIKV-----GRPSN 87
>16427
          Length = 1313

 Score = 36.2 bits (82), Expect = 0.012,   Method: Compositional matrix adjust.
 Identities = 22/78 (28%), Positives = 34/78 (43%)
 Frame = +1

Query: 16  LKVDNLTYRTSPDTLRRVFEKYGRVGDVYIPRDRYTKESRGFAFVRFHDKRXXXXXXXXX 75
           L V  L        L R F K+GR+ +  + RD+  + SRGF FV + +           
Sbjct: 142 LFVGGLAEEIDEKVLEREFSKFGRITESMVIRDKVRQVSRGFGFVTYENPMDAEEAVKHM 321

Query: 76  XXXVLDGRELRVQMARYG 93
               + G++L V+ A  G
Sbjct: 322 DGKEILGKKLHVEDAVRG 375
>05273
          Length = 1009

 Score = 36.2 bits (82), Expect = 0.012,   Method: Compositional matrix adjust.
 Identities = 16/42 (38%), Positives = 26/42 (61%)
 Frame = -1

Query: 25  TSPDTLRRVFEKYGRVGDVYIPRDRYTKESRGFAFVRFHDKR 66
           T+  +LR  F+K+G + +  +  DR T +SRG+ FV   D+R
Sbjct: 166 TTDHSLREYFDKFGDIDEAVVITDRQTGKSRGYGFVTMADRR 41
>02140
          Length = 1796

 Score = 35.8 bits (81), Expect = 0.016,   Method: Compositional matrix adjust.
 Identities = 23/87 (26%), Positives = 38/87 (43%)
 Frame = +3

Query: 5   RPPPDVEGMTSLKVDNLTYRTSPDTLRRVFEKYGRVGDVYIPRDRYTKESRGFAFVRFHD 64
           +PP +V     L V  L   T+ + L  +F ++G +    + RD  TKES  +AFV F  
Sbjct: 789 KPPDNV-----LFVCKLNPVTTDEDLEMIFSRFGPITSCEVIRDHKTKESLQYAFVEFEK 953

Query: 65  KRXXXXXXXXXXXXVLDGRELRVQMAR 91
                         ++D R + V  ++
Sbjct: 954 PEHCENAYFKMDNVLIDDRRIHVDFSQ 1034
>01937
          Length = 1320

 Score = 32.0 bits (71), Expect = 0.22,   Method: Compositional matrix adjust.
 Identities = 16/56 (28%), Positives = 29/56 (51%)
 Frame = -1

Query: 10   VEGMTSLKVDNLTYRTSPDTLRRVFEKYGRVGDVYIPRDRYTKESRGFAFVRFHDK 65
            V   + + V  L+  T+ +  +  F+ YG + +  +  D+ T   RGFAFV F ++
Sbjct: 1227 VTKTSKIFVGGLSSSTTVEDXKNYFKAYGTIEEATLMFDKVTSRHRGFAFVTFDNE 1060
>08670
          Length = 1307

 Score = 31.2 bits (69), Expect = 0.31,   Method: Compositional matrix adjust.
 Identities = 19/66 (28%), Positives = 33/66 (50%), Gaps = 7/66 (10%)
 Frame = +2

Query: 7   PPDVEGMTSLKVDNLTYRTSPDTLRRVFEKYGRVGDVYIPRDRYT-------KESRGFAF 59
           P + EG+T+L V N+  + +   L ++F K+G V  V +  ++Y        KES G A 
Sbjct: 932 PKNPEGLTALWVGNVLPQVTEKRLTQMFAKHGPVASVRMLPEKYCAFINYKLKESAGRAM 1111

Query: 60  VRFHDK 65
               ++
Sbjct: 1112QYLQNQ 1129
>23250
          Length = 1617

 Score = 28.1 bits (61), Expect = 2.6,   Method: Compositional matrix adjust.
 Identities = 12/33 (36%), Positives = 21/33 (63%)
 Frame = -1

Query: 30   LRRVFEKYGRVGDVYIPRDRYTKESRGFAFVRF 62
            ++R F ++GRV  + + R   T  S+G+AF+ F
Sbjct: 1287 MKRFFSQFGRVTRLRLSRSTKTGGSKGYAFLEF 1189
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|9937996|ref|NP_064662.1| DnaJ (Hsp40) homolog,
subfamily B, member 2 isoform 1 [Mus musculus]
         (259 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

02324                                                                  55   2e-08
13998                                                                  49   2e-06
07620                                                                  48   3e-06
14550                                                                  43   2e-04
15360                                                                  37   0.011
26984                                                                  36   0.014
22505                                                                  36   0.019
02088                                                                  35   0.036
02956                                                                  29   1.7  
13422                                                                  29   2.1  
33510                                                                  28   3.9  
17270                                                                  27   7.1  
>02324
          Length = 2058

 Score = 55.5 bits (132), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 24/38 (63%), Positives = 31/38 (81%)
 Frame = +2

Query: 1   MASYYEILDVPRSASPDDIKKAYRKKALQWHPDKNPDN 38
           +  +YE+L V RSA  DD+KKAYRK AL++HPDKNPD+
Sbjct: 98  IRCHYEVLGVERSADNDDLKKAYRKLALKFHPDKNPDS 211
>13998
          Length = 1075

 Score = 48.5 bits (114), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 20/34 (58%), Positives = 28/34 (82%)
 Frame = +1

Query: 4   YYEILDVPRSASPDDIKKAYRKKALQWHPDKNPD 37
           YY+IL + R+A+ D+IKKAYRKKAL  HPD++ +
Sbjct: 208 YYKILGISRNATEDEIKKAYRKKALVHHPDRHAN 309
>07620
          Length = 1775

 Score = 48.1 bits (113), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 20/32 (62%), Positives = 24/32 (75%)
 Frame = +1

Query: 4   YYEILDVPRSASPDDIKKAYRKKALQWHPDKN 35
           YYE+LDV +  +  D+KKAYRK ALQ HPDK 
Sbjct: 103 YYEVLDVKKDCTESDMKKAYRKLALQMHPDKT 198
>14550
          Length = 1395

 Score = 42.7 bits (99), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 19/35 (54%), Positives = 25/35 (71%)
 Frame = -1

Query: 4    YYEILDVPRSASPDDIKKAYRKKALQWHPDKNPDN 38
            +Y+IL V +SA    IK+AYRK A + HPDKN D+
Sbjct: 1131 FYKILGVSKSADTKQIKRAYRKIAKELHPDKNRDD 1027
>15360
          Length = 502

 Score = 36.6 bits (83), Expect = 0.011,   Method: Compositional matrix adjust.
 Identities = 11/33 (33%), Positives = 23/33 (69%)
 Frame = +1

Query: 5  YEILDVPRSASPDDIKKAYRKKALQWHPDKNPD 37
          + +LD+P  +  + +K  Y++ AL+WHP+K+ +
Sbjct: 61 FNLLDIPAGSDQESLKTKYKQLALKWHPEKHKN 159
>26984
          Length = 1107

 Score = 36.2 bits (82), Expect = 0.014,   Method: Compositional matrix adjust.
 Identities = 16/31 (51%), Positives = 22/31 (70%)
 Frame = -2

Query: 5   YEILDVPRSASPDDIKKAYRKKALQWHPDKN 35
           Y IL +   AS +DIK+ YR++A+  HPDKN
Sbjct: 509 YSILGLRADASDEDIKRYYRRQAVLVHPDKN 417
>22505
          Length = 784

 Score = 35.8 bits (81), Expect = 0.019,   Method: Compositional matrix adjust.
 Identities = 18/31 (58%), Positives = 20/31 (64%)
 Frame = -1

Query: 5   YEILDVPRSASPDDIKKAYRKKALQWHPDKN 35
           Y IL V   A+   I KAYRKKAL+ HPDK 
Sbjct: 646 YGILGVGPEANEKQIVKAYRKKALKCHPDKT 554
>02088
          Length = 1062

 Score = 34.7 bits (78), Expect = 0.036,   Method: Compositional matrix adjust.
 Identities = 13/30 (43%), Positives = 21/30 (70%)
 Frame = +3

Query: 5   YEILDVPRSASPDDIKKAYRKKALQWHPDK 34
           YE++ + R A+P ++KK Y K +L  HPD+
Sbjct: 114 YEVIGIRREATPQEVKKGYHKVSLAVHPDQ 203
>02956
          Length = 948

 Score = 29.3 bits (64), Expect = 1.7,   Method: Compositional matrix adjust.
 Identities = 26/75 (34%), Positives = 37/75 (49%), Gaps = 14/75 (18%)
 Frame = +3

Query: 191 PDDLALGLELSRREQ-----QPSVAP-GLGVMQVRPTSLSRPPDH--------DLSEDED 236
           P D+ LGL++ +R Q     Q +V   G    + R  + S+ P H        D + DED
Sbjct: 162 PMDMLLGLDMLKRHQCIIDLQHNVLKFGTTGTETRFLTESQLPQHARLNNTQPDTAMDED 341

Query: 237 LQLAMAYSLSEMEAA 251
            QLA A S S+ E+A
Sbjct: 342 QQLAQAISQSQQESA 386
>13422
          Length = 930

 Score = 28.9 bits (63), Expect = 2.1,   Method: Compositional matrix adjust.
 Identities = 14/34 (41%), Positives = 21/34 (61%), Gaps = 3/34 (8%)
 Frame = +1

Query: 4   YYEILDVPR---SASPDDIKKAYRKKALQWHPDK 34
           +Y +L + +    A+ D IK+ YR+K L  HPDK
Sbjct: 340 HYAVLGLSKLRYKATADHIKRIYRQKVLLHHPDK 441
>33510
          Length = 501

 Score = 28.1 bits (61), Expect = 3.9,   Method: Compositional matrix adjust.
 Identities = 13/25 (52%), Positives = 15/25 (60%)
 Frame = +3

Query: 14  ASPDDIKKAYRKKALQWHPDKNPDN 38
            S D +KK YRK  L  HPDK  D+
Sbjct: 291 VSADQVKKVYRKAVLSVHPDKLHDD 365
>17270
          Length = 1144

 Score = 27.3 bits (59), Expect = 7.1,   Method: Compositional matrix adjust.
 Identities = 12/24 (50%), Positives = 18/24 (75%), Gaps = 2/24 (8%)
 Frame = +3

Query: 13  SASPD--DIKKAYRKKALQWHPDK 34
           SA+P+  +IKK Y+K  + +HPDK
Sbjct: 312 SANPEWTEIKKLYQKAVIHYHPDK 383
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|10946572|ref|NP_067247.1| fatty acid binding protein
7, brain [Mus musculus]
         (132 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

07957                                                                  53   3e-08
14358                                                                  45   1e-05
03045                                                                  28   0.77 
03139                                                                  28   0.84 
26864                                                                  28   1.4  
00846                                                                  27   2.1  
31753                                                                  27   2.7  
08540                                                                  26   3.8  
>07957
          Length = 883

 Score = 53.1 bits (126), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 32/125 (25%), Positives = 57/125 (45%)
 Frame = +1

Query: 1   MVDAFCATWKLTDSQNFDEYMKALGVGFATRQVGNVTKPTVIISQEGGKVVIRTQCTFKN 60
           M D     W+    +N D     +GV  A RQ     K  + I ++GG+  + T    K+
Sbjct: 259 MADGLIGKWQSVSYENMDPLWDVMGVPDAMRQFARDKKTELTIEKDGGQWKLTTVAGDKS 438

Query: 61  TEINFQLGEEFEETSIDDRNCKSVVRLDGDKLIHVQKWDGKETNCTREIKDGKMVVTLTF 120
             I F +G+E +  ++     K+++  +G +L+  QK    E    R ++DGK+   +T 
Sbjct: 439 RVIVFPVGQEVDTITLMGEPVKAILTEEGGQLVERQKAGVGEIIIQRSLQDGKLKTNMTL 618

Query: 121 GDIVA 125
             + A
Sbjct: 619 KGVTA 633
>14358
          Length = 996

 Score = 44.7 bits (104), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 32/98 (32%), Positives = 48/98 (48%), Gaps = 10/98 (10%)
 Frame = +1

Query: 45  QEGGKVVIRTQCTFKNTEINFQLGEEFEETSIDDR----------NCKSVVRLDGDKLIH 94
           Q+ GK+VIRT  TF  +E++F+L EE+EE +   +          N K  V     + I 
Sbjct: 16  QDDGKIVIRTNSTFMKSEVSFKLNEEYEEINPHSKKKFXNMPTYENGKLRVTPTPAEPID 195

Query: 95  VQKWDGKETNCTREIKDGKMVVTLTFGDIVAVRCYEKA 132
           V   +  E   T    DG+M+VTL   D+   R ++K 
Sbjct: 196 VPYPEYXEREIT---DDGEMLVTLKVEDVXCKRWFKKV 300
>03045
          Length = 1281

 Score = 28.5 bits (62), Expect = 0.77,   Method: Compositional matrix adjust.
 Identities = 17/35 (48%), Positives = 21/35 (60%)
 Frame = +2

Query: 4   AFCATWKLTDSQNFDEYMKALGVGFATRQVGNVTK 38
           +FC T KL DS   DE+   LGVGF+   VG V +
Sbjct: 308 SFC-TAKLVDS--LDEHGAYLGVGFSLLGVGQVLQ 403
>03139
          Length = 1372

 Score = 28.5 bits (62), Expect = 0.84,   Method: Compositional matrix adjust.
 Identities = 16/52 (30%), Positives = 29/52 (55%), Gaps = 1/52 (1%)
 Frame = -3

Query: 81   CKSVVRLDGDKLIHVQKWDGK-ETNCTREIKDGKMVVTLTFGDIVAVRCYEK 131
             K+V  ++GD L  V+   G   T   R ++  +M++T+  GD+ + R Y+K
Sbjct: 1370 IKTVFTIEGDTL--VENVSGPLSTVIVRAVEGSQMIMTMKSGDVTSTRKYDK 1221
>26864
          Length = 768

 Score = 27.7 bits (60), Expect = 1.4,   Method: Compositional matrix adjust.
 Identities = 17/84 (20%), Positives = 33/84 (39%)
 Frame = -3

Query: 28  FATRQVGNVTKPTVIISQEGGKVVIRTQCTFKNTEINFQLGEEFEETSIDDRNCKSVVRL 87
            +TR+   +    ++  +    V +R+  T    +   Q     +  + D R+  S+   
Sbjct: 739 LSTREASRLVWGVLMKRRAWLGVTLRSHMTMCTWQGGMQGWPGVKRVNTDFRSSHSIHEW 560

Query: 88  DGDKLIHVQKWDGKETNCTREIKD 111
            G  LI   KW G    CT ++ +
Sbjct: 559 SGAFLIQEMKWSGFRLYCTTDVTE 488
>00846
          Length = 4234

 Score = 27.3 bits (59), Expect = 2.1,   Method: Compositional matrix adjust.
 Identities = 12/33 (36%), Positives = 18/33 (54%)
 Frame = -3

Query: 88   DGDKLIHVQKWDGKETNCTREIKDGKMVVTLTF 120
            + DKL+ +Q W  KE +   +IK    V+  TF
Sbjct: 4169 EKDKLVEIQTWPMKENDTIHQIKIFYTVLFFTF 4071
>31753
          Length = 374

 Score = 26.9 bits (58), Expect = 2.7,   Method: Compositional matrix adjust.
 Identities = 10/23 (43%), Positives = 13/23 (56%)
 Frame = -3

Query: 4   AFCATWKLTDSQNFDEYMKALGV 26
           A    WKL    NF+ Y+ A+GV
Sbjct: 222 ALNGKWKLVSVDNFESYLDAVGV 154
>08540
          Length = 2044

 Score = 26.2 bits (56), Expect = 3.8,   Method: Composition-based stats.
 Identities = 9/35 (25%), Positives = 19/35 (54%)
 Frame = +1

Query: 98  WDGKETNCTREIKDGKMVVTLTFGDIVAVRCYEKA 132
           WD  +  C+  I  G++   + F +   ++CY++A
Sbjct: 697 WDNSQAECSLSIVVGQLFTRVGFRNWKWMKCYQQA 801
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|113199781|ref|NP_666151.3| WD repeat domain 60 [Mus
musculus]
         (999 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

20271                                                                  57   3e-08
12841                                                                  49   1e-05
01768                                                                  41   0.003
03387                                                                  39   0.007
14105                                                                  32   0.95 
37142                                                                  30   5.2  
06799                                                                  30   6.5  
13335                                                                  29   7.7  
>20271
          Length = 567

 Score = 57.4 bits (137), Expect = 3e-08,   Method: Composition-based stats.
 Identities = 41/149 (27%), Positives = 71/149 (47%), Gaps = 5/149 (3%)
 Frame = -1

Query: 793 LSHKDSELWGSTQTLSVKFLPSDPNHFVVGTDMGLISHSTRQDWRVS-PRVFKPEQHGVR 851
           L HK S+   S       FL  D N+F+VG++  L+  ++R   +      ++  Q  + 
Sbjct: 441 LQHKQSK---SVAATCFSFLSGDANNFIVGSEECLVYSASRHGSKAGINEAYEGHQGPIT 271

Query: 852 PIKVN----VIDFSPFEETVFLAGCSDGSIRLHQLTSERPIMQWDNSTSGHAVTSLQWSP 907
            I  +     IDFSPF    FL    D +++L  +  ++ +  +++++    V+ +QWSP
Sbjct: 270 AIDTHHAAGQIDFSPF----FLTASFDWTVKLWNIKEQKYVCSFEDNSD--YVSDVQWSP 109

Query: 908 TRPAVFLVQDDASRIYVWDLLENDLGPVA 936
           T PA+F   D   R+ +W L      P A
Sbjct: 108 TNPALFSCVDIMGRLDLWHLNHETEVPTA 22
>12841
          Length = 1364

 Score = 48.5 bits (114), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 43/145 (29%), Positives = 63/145 (43%), Gaps = 1/145 (0%)
 Frame = +1

Query: 807  LSVKFLPSDPNHFVVGTDMGLISHSTRQDWRVSPRVFKPEQHGVRPIKVNVIDFSPFEET 866
            L   F   D N ++ GT+ G I   +      S      E +      V  I +SPF   
Sbjct: 928  LCFDFHSRDLNVYLAGTEEGYIHKCS-----CSYNEQYLETYSGHTAPVYHIRWSPFVSD 1092

Query: 867  VFLAGCSDGSIRLHQLTSERPIMQWDNSTSGHAVTSLQWSPTRPAVFLVQDDASRIYVWD 926
            +FL+  +D SIRL       PI+ + +ST    V  + WSP    VF    + + + VWD
Sbjct: 1093 IFLSCSADWSIRLWHQDRTTPILTFHSST--KTVHDVCWSPRSSTVFACVHEGA-VEVWD 1263

Query: 927  LLENDLGPVAQ-QPISPDKLVAMTI 950
            L ++ L  V    P S  KL ++T 
Sbjct: 1264 LAQSTLDAVITITPTSGAKLTSVTF 1338

 Score = 40.8 bits (94), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 26/94 (27%), Positives = 40/94 (42%)
 Frame = +1

Query: 580 PFLQSRKVSCLHASRVQRQTVVSVHDLPEKAFAPSLDSRHLLCVWDIWQPSGPQKVLICE 639
           P  + R VSCL  ++     V     +    F  +     L+C W +  P  P++V    
Sbjct: 388 PLTKGRNVSCLAWNKSNPDLVA----VGYGQFDFTNQKSGLICCWSLKNPEYPERVYTST 555

Query: 640 SKVTCCCFSPLKAFLLFAGTVHGSVVVWDLREDS 673
             VT   FS   A +L AG   G V ++++R  S
Sbjct: 556 HGVTSLDFSVANANILAAGYYDGGVAIYNVRSTS 657
>01768
          Length = 1424

 Score = 40.8 bits (94), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 34/123 (27%), Positives = 58/123 (47%), Gaps = 4/123 (3%)
 Frame = +3

Query: 809 VKFLPSDPNHFV-VGTDMGLISHSTRQDWRVSPRVFKPEQHGVRPIKVNVIDFSPFEETV 867
           V++ P++ N F     D  L   +T+Q    +  +  PE H      +NVI+++P E+ +
Sbjct: 855 VQWSPNEGNVFASCSVDRTLRIWNTQQKPSKANVLTVPEAHSR---DINVINWNPIEKHL 1025

Query: 868 FLAGCSDGSIRLHQLTSER--PI-MQWDNSTSGHAVTSLQWSPTRPAVFLVQDDASRIYV 924
             +G  DG I++  L   R  P+  Q         VTSL+W+P   +V     +  +I +
Sbjct: 1026LASGGDDGIIKIWDLRMFRNKPVSAQASFKLHSQPVTSLEWNPQDSSVLAASGEDDQITI 1205

Query: 925 WDL 927
           WD 
Sbjct: 1206WDF 1214
>03387
          Length = 1891

 Score = 39.3 bits (90), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 36/129 (27%), Positives = 57/129 (44%), Gaps = 12/129 (9%)
 Frame = +1

Query: 554 GPSWIPRAQDKALNISD---------SSSQLNTSLPFLQSRKVSCLHASRVQRQTVVSVH 604
           G SW P      L+ SD         +S+Q  + +  + +  +   H S V+    V+ H
Sbjct: 376 GLSWNPNLNGHLLSASDDHTICLWDINSTQRESRV--VDAHTIFTGHTSVVED---VAWH 540

Query: 605 DLPEKAFAPSLDSRHLLCVWDIWQ--PSGPQKVLICES-KVTCCCFSPLKAFLLFAGTVH 661
            L E  F    D + L+ +WD      S P  V+   + +V C  F+P   F+L  G+  
Sbjct: 541 LLHESLFGSVADDQKLM-IWDTRSNTTSKPSHVVDAHTAEVNCLSFNPYSEFILATGSAD 717

Query: 662 GSVVVWDLR 670
            +V +WDLR
Sbjct: 718 KTVALWDLR 744

 Score = 37.0 bits (84), Expect = 0.039,   Method: Compositional matrix adjust.
 Identities = 20/76 (26%), Positives = 36/76 (47%), Gaps = 2/76 (2%)
 Frame = +1

Query: 854 KVNVIDFSPFEETVFLAGCSDGSIRLHQLTSERPIMQWDNSTSGHA--VTSLQWSPTRPA 911
           +VN + F+P+ E +   G +D ++ L  L + +  +    S   H   +  +QWSP    
Sbjct: 655 EVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLH---SFESHKDEIFQVQWSPHNET 825

Query: 912 VFLVQDDASRIYVWDL 927
           +        R++VWDL
Sbjct: 826 ILASSGTDRRLHVWDL 873
>14105
          Length = 429

 Score = 32.3 bits (72), Expect = 0.95,   Method: Compositional matrix adjust.
 Identities = 29/121 (23%), Positives = 54/121 (44%)
 Frame = +3

Query: 879 LHQLTSERPIMQWDNSTSGHAVTSLQWSPTRPAVFLVQDDASRIYVWDLLENDLGPVAQQ 938
           L  L   +P+  +++++    V  + WSP  PA+F   D + R+ +W+L ++   P A  
Sbjct: 3   LWSLKDTKPLYSFEDNSD--YVMDVAWSPVHPALFAAVDGSGRLDLWNLNQDTEVPTAS- 173

Query: 939 PISPDKLVAMTIVGEPEKTSGSFVALVLARTSGTVDVQNLKRRWTTPAVDEHSQLRLLLQ 998
            I  D   A+  V      + S + + +   SG + V ++      P  DE S+    L 
Sbjct: 174 -IVVDGAPALNRV----SWTPSGLHVTIGDESGKLYVYDVAEHLALPTRDEWSRFNATLN 338

Query: 999 K 999
           +
Sbjct: 339 E 341
>37142
          Length = 327

 Score = 30.0 bits (66), Expect = 5.2,   Method: Composition-based stats.
 Identities = 18/72 (25%), Positives = 33/72 (45%), Gaps = 1/72 (1%)
 Frame = +2

Query: 855 VNVIDFSPFEETVFLAGCSDGSIRLHQLTS-ERPIMQWDNSTSGHAVTSLQWSPTRPAVF 913
           V  +DF+PF+  +  +G S+  I +  L   + P+     S     V+ + W+     + 
Sbjct: 113 VKALDFNPFQTNLLASGASESEIYIWDLNKPDNPMTPGQKSQPPEEVSCVAWNRQVQHI- 289

Query: 914 LVQDDASRIYVW 925
           L  + A+R  VW
Sbjct: 290 LASNFAARCVVW 325
>06799
          Length = 616

 Score = 29.6 bits (65), Expect = 6.5,   Method: Compositional matrix adjust.
 Identities = 20/66 (30%), Positives = 33/66 (50%), Gaps = 6/66 (9%)
 Frame = +3

Query: 648 SPLKAFLLFAGTVHGSVVVWDLRE---DSRIHHYVRLSNCFWAFRTPTFS---TDGILTS 701
           +P+ +  L  G   G++V+WDLR    + R +    L +  W F    F    +DG LT+
Sbjct: 300 NPVDSNKLLIGFESGAIVLWDLRSKAAECRYNSPEALRSIAWHFEGKQFMCSHSDGSLTT 479

Query: 702 VNHRSP 707
            N ++P
Sbjct: 480 WNLKAP 497
>13335
          Length = 863

 Score = 29.3 bits (64), Expect = 7.7,   Method: Composition-based stats.
 Identities = 24/115 (20%), Positives = 46/115 (40%)
 Frame = +1

Query: 561 AQDKALNISDSSSQLNTSLPFLQSRKVSCLHASRVQRQTVVSVHDLPEKAFAPSLDSRHL 620
            +D  + +   S+Q+ +    LQ R +   H+       V++    P  A   S      
Sbjct: 415 GKDNLIKLWTFSAQVGSPEVTLQCRDILSGHSD-----LVMACAFSPSSALLASGSFDKS 579

Query: 621 LCVWDIWQPSGPQKVLICESKVTCCCFSPLKAFLLFAGTVHGSVVVWDLREDSRI 675
           + +WD  +      +  C S+   CC   +   LL +G++   + +W L + S I
Sbjct: 580 VRLWDSVKGVALFSIEACHSRFVTCCAFSIDGTLLASGSMDRIIKIWKLTDTSSI 744
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|23956320|ref|NP_705773.1| leucine rich repeat
containing 45 [Mus musculus]
         (670 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

19912                                                                  57   3e-08
19107                                                                  49   5e-06
31609                                                                  46   5e-05
15500                                                                  34   0.25 
03942                                                                  28   8.6  
>19912
          Length = 865

 Score = 57.0 bits (136), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 43/146 (29%), Positives = 70/146 (47%), Gaps = 5/146 (3%)
 Frame = +1

Query: 82  LCANTSVQHLDLKGNNLRATGAEALGKLLRQNKSIQSLTLEWNNLGTWEDAFATFCGGLA 141
           +   T ++++DL  NNL   G + LG  +  N SI+ L L WN+L            G+ 
Sbjct: 43  IATTTRMEYVDLSHNNLGEAGGQHLGPAISDNISIKELNLAWNHLR--RKGAVAVAAGVK 216

Query: 142 ANSALRQLDLRNNQISHKGAEELALALKGNTTLQQLDLRWNNIGLLGGRALVNCLPSNRT 201
            N  +++++L  N   H+GA  L+ A+K N+ L++LD+  N I   G   +   L  N T
Sbjct: 217 TNVTMKRINLSWNGFGHEGAIALSSAVKENSVLEELDIMNNRISTEGAVLIGKGLSLNET 396

Query: 202 LWKLDLAGN-----NIPGDILRAVEQ 222
           L    +  N        GD+ R +E+
Sbjct: 397 LRVFKIGKNPMQSAGCWGDLCRHLEK 474
>19107
          Length = 936

 Score = 49.3 bits (116), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 55/185 (29%), Positives = 77/185 (41%), Gaps = 30/185 (16%)
 Frame = -1

Query: 73  EGSTLLFQGLCANTSVQHLDLKGNNLRATGAEALGKLLRQNKSIQSLTLEWNNLGT-WED 131
           +G     Q L  NT+++HLDL   +LR     ALG +L  N +++S+ +    L T  E+
Sbjct: 936 KGGMYFAQALQINTTLEHLDLGDTDLRTESLIALGTVLLHNVTLRSININRPILFTQMEE 757

Query: 132 AFATFCG----------------------------GLAANSALRQLDLRNNQISHKGAEE 163
               F                               L  N  L  L+L  N+I+  G +E
Sbjct: 756 PSVHFANMLKVNQSLEEVHLQKYDMRDFGAFRMAENLMHNYTLTYLNLSCNRITRDGVKE 577

Query: 164 LALALKGNTTLQQLDLRWNNIGLLGGRALVNCLPS-NRTLWKLDLAGNNIPGDILRAVEQ 222
           LA  LK NT LQ LDL +N +   G   +   L + N  L  L +  NNI    L A+  
Sbjct: 576 LAKVLKQNTALQTLDLGYNRLEDDGAIHIAEALTTLNTKLQCLVVVHNNIGSAGLCAIAD 397

Query: 223 AMDHN 227
           AM  N
Sbjct: 396 AMKTN 382
>31609
          Length = 841

 Score = 46.2 bits (108), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 30/94 (31%), Positives = 51/94 (54%)
 Frame = +2

Query: 103 AEALGKLLRQNKSIQSLTLEWNNLGTWEDAFATFCGGLAANSALRQLDLRNNQISHKGAE 162
           A  +G+++ +N+ +QS++L  N      DA   F   +     LR+LDL +N++S   A 
Sbjct: 80  AVVMGRIMMENRVLQSVSLAGNGFKD-TDA-VNFTQVIMDRRPLRELDLSHNELSDGAAV 253

Query: 163 ELALALKGNTTLQQLDLRWNNIGLLGGRALVNCL 196
           +    L  N  L+ LDL WN+I   GG A+++ +
Sbjct: 254 QFGEGLVNNDILEVLDLSWNHIRPRGGVAIMHGV 355
>15500
          Length = 550

 Score = 33.9 bits (76), Expect = 0.25,   Method: Composition-based stats.
 Identities = 28/84 (33%), Positives = 40/84 (47%)
 Frame = +2

Query: 85  NTSVQHLDLKGNNLRATGAEALGKLLRQNKSIQSLTLEWNNLGTWEDAFATFCGGLAANS 144
           N S++   L  +N    G  ALG L   NK + +L L  N++   +   +    GL  N 
Sbjct: 176 NLSLRFCGLTNSNAAGFG-RALGTLSTWNKKLLTLNLSHNSIT--DLGVSHLAHGLMTNR 346

Query: 145 ALRQLDLRNNQISHKGAEELALAL 168
            L  L+L +NQI  +GA  LA  L
Sbjct: 347 TLLVLNLASNQIGDEGAAALAQVL 418
>03942
          Length = 912

 Score = 28.5 bits (62), Expect = 8.6,   Method: Compositional matrix adjust.
 Identities = 21/59 (35%), Positives = 26/59 (44%), Gaps = 2/59 (3%)
 Frame = -1

Query: 74  GSTLLFQGLCANT--SVQHLDLKGNNLRATGAEALGKLLRQNKSIQSLTLEWNNLGTWE 130
           G T    G C +   SV  LDLK + L + G   L K L    S   LTL+    G W+
Sbjct: 516 GYTFFILGFCLDIFDSVTGLDLKCDGLPSQG---LYKDLHYATSAVLLTLKXLXFGAWK 349
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6753264|ref|NP_035927.1| carbonic anhydrase 14 [Mus
musculus]
         (337 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

35985                                                                  55   3e-08
25693                                                                  54   7e-08
17230                                                                  49   3e-06
17466                                                                  35   0.035
05853                                                                  34   0.068
13738                                                                  29   2.9  
04725                                                                  28   4.9  
01987                                                                  28   5.0  
03513                                                                  28   6.2  
22289                                                                  28   6.4  
07708                                                                  28   6.7  
>35985
          Length = 475

 Score = 55.5 bits (132), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 46/131 (35%), Positives = 62/131 (47%), Gaps = 3/131 (2%)
 Frame = +3

Query: 2   LFFALLLKVTWILAADGGHHWTYEGPHGQDHWPTSYPE-CGGDAQSPINIQTDSVIFDPD 60
           L+   L+ V      D    W+YEG +G  HW   +P+ C G  QSPI+IQ     FD +
Sbjct: 48  LYAVCLIAVLLATETDATSTWSYEGHNGPHHWHQLFPQACSGKYQSPIDIQPADTRFDSN 227

Query: 61  LPAVQPHGYDQLGTEPLDLHNNGHTVQLSLPPTLHL--GGLPRKYTAAQLHLHWGQRGSL 118
           L               + + NNGHTVQ+     L++  GGLP  Y A Q H H       
Sbjct: 228 LNDFAIWYDPPRPGASMVVSNNGHTVQVLTKGELYVANGGLPYVYRATQFHFH-WGHAHH 404

Query: 119 EGSEHQINSEA 129
            GSEH I+++A
Sbjct: 405 HGSEHLIDNQA 437
>25693
          Length = 428

 Score = 54.3 bits (129), Expect = 7e-08,   Method: Compositional matrix adjust.
 Identities = 37/137 (27%), Positives = 68/137 (49%), Gaps = 21/137 (15%)
 Frame = -2

Query: 35  TSYPECGGDAQSPINIQTDSVIFDPDLPAVQPHGYDQLGTEPLDLHNNGHTVQL------ 88
           T  PE  G  QSP+++ +    ++ +L A  P  ++   +   D+ NNG+T+ +      
Sbjct: 409 TVLPEATGSRQSPVDVVSCDAKYE-ELLANTPLQFNYATSRETDILNNGYTLVVFPRAKQ 233

Query: 89  -------------SLPPTLHLGGLPR--KYTAAQLHLHWGQRGSLEGSEHQINSEATAAE 133
                            ++  G LP+  +Y  A++  HWG+  S  GSEH +N++A   E
Sbjct: 232 VESQTSHRADLASHTASSVSGGPLPQGMEYELAEIRFHWGRENS-RGSEHTVNNKAFPME 56

Query: 134 LHVVHYDSQSYSSLSEA 150
           + +VH++++ Y S+ EA
Sbjct: 55  VQLVHWNTRLYESIEEA 5
>17230
          Length = 486

 Score = 48.9 bits (115), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 35/108 (32%), Positives = 51/108 (47%), Gaps = 6/108 (5%)
 Frame = +3

Query: 1   MLFFALLLKVTWILAADGGHHWTYEGPHGQDHWPTSYPECGGDAQSPINIQTDSVIFDPD 60
           + F A ++     L A+    + Y GP G DHW   Y +C G  QSPINI   +V     
Sbjct: 168 LRFVAGVILACVALVAE--QDFGYGGPIGPDHWRDDYQQCSGKYQSPININVLNVTKKEF 341

Query: 61  LPAVQPHGYDQLGTEPLDLHNNGHTVQLSLP------PTLHLGGLPRK 102
            P    + Y++   E + + NNGHTV +++       P +  G L RK
Sbjct: 342 PPLTYENFYER--PEEILITNNGHTVLVTMKFKKGKEPRVKGGPLERK 479
>17466
          Length = 513

 Score = 35.4 bits (80), Expect = 0.035,   Method: Compositional matrix adjust.
 Identities = 14/34 (41%), Positives = 17/34 (50%)
 Frame = -1

Query: 22  WTYEGPHGQDHWPTSYPECGGDAQSPINIQTDSV 55
           W Y    G   WP  +P C G  QSP+NI+   V
Sbjct: 273 WDYSQGKGPVAWPFKFPACSGLRQSPVNIERSRV 172
>05853
          Length = 1463

 Score = 34.3 bits (77), Expect = 0.068,   Method: Compositional matrix adjust.
 Identities = 15/40 (37%), Positives = 19/40 (47%)
 Frame = -2

Query: 96  LGGLPRKYTAAQLHLHWGQRGSLEGSEHQINSEATAAELH 135
           L   PR+ + AQLHL W QR  L+  + Q         LH
Sbjct: 748 LPSFPRQKSCAQLHLLWKQRPRLQTKQAQCQIPCCLPRLH 629
>13738
          Length = 1186

 Score = 28.9 bits (63), Expect = 2.9,   Method: Compositional matrix adjust.
 Identities = 14/45 (31%), Positives = 22/45 (48%)
 Frame = -2

Query: 164 IEVGETENPAYDHILSRLHEIRYKDQKTSVPPFSVRELFPQQLEQ 208
           I +G+     Y    +R H+ RY     S+P  S++ LFP   +Q
Sbjct: 636 INIGQYI*STYIKHTTRFHDRRYSSNLQSLPVASLKTLFPSTFQQ 502
>04725
          Length = 2535

 Score = 28.1 bits (61), Expect = 4.9,   Method: Compositional matrix adjust.
 Identities = 9/30 (30%), Positives = 19/30 (63%)
 Frame = +1

Query: 170  ENPAYDHILSRLHEIRYKDQKTSVPPFSVR 199
            +NPAYD +L+ L ++++  +   + P  +R
Sbjct: 1141 DNPAYDSVLNPLFQLKFDQKPKEIKPLGLR 1230
>01987
          Length = 1965

 Score = 28.1 bits (61), Expect = 5.0,   Method: Compositional matrix adjust.
 Identities = 15/51 (29%), Positives = 24/51 (47%), Gaps = 2/51 (3%)
 Frame = +3

Query: 67   HGYDQLGTEPLDLHNNGHTVQLSLPPTLHLGGLPRKY--TAAQLHLHWGQR 115
            H Y  +  +P DL  +G   +  +PPT+H   L   +     +  +HW QR
Sbjct: 1389 HAYFHIRLKPFDLSTSGLPQRGVVPPTMHSQLLQNVF*SRPVEFRIHWQQR 1541
>03513
          Length = 1394

 Score = 27.7 bits (60), Expect = 6.2,   Method: Compositional matrix adjust.
 Identities = 16/45 (35%), Positives = 26/45 (57%), Gaps = 1/45 (2%)
 Frame = +3

Query: 104 TAAQLHLHWGQRGSLEGSEHQI-NSEATAAELHVVHYDSQSYSSL 147
           T   L+ HWG++ +    E ++ N  +T+      H+DSQS+SSL
Sbjct: 819 TKTSLNNHWGEKSTKYVGEGRLSNCFSTSLAF*FQHFDSQSHSSL 953
>22289
          Length = 586

 Score = 27.7 bits (60), Expect = 6.4,   Method: Compositional matrix adjust.
 Identities = 10/31 (32%), Positives = 16/31 (51%)
 Frame = +1

Query: 168 ETENPAYDHILSRLHEIRYKDQKTSVPPFSV 198
           E  NPAYD + +     ++ D  T +PP  +
Sbjct: 91  EPTNPAYDCVFNPKFMKKFDDSPTCIPPLGI 183
>07708
          Length = 1263

 Score = 27.7 bits (60), Expect = 6.7,   Method: Compositional matrix adjust.
 Identities = 13/35 (37%), Positives = 17/35 (48%), Gaps = 1/35 (2%)
 Frame = +2

Query: 21  HWTYEGPHGQDHWPTSY-PECGGDAQSPINIQTDS 54
           HWT+ G    DHWP+ +   CG D   P     D+
Sbjct: 86  HWTWSGSCLSDHWPSRWLILCGCDQLCPACRHGDT 190
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|183396771|ref|NP_034607.3| heat shock protein 1
(chaperonin) [Mus musculus]
         (573 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

01159                                                                  56   4e-08
29864                                                                  42   5e-04
33770                                                                  42   7e-04
21557                                                                  31   1.1  
>01159
          Length = 2613

 Score = 55.8 bits (133), Expect = 4e-08,   Method: Compositional matrix adjust.
 Identities = 80/340 (23%), Positives = 145/340 (42%), Gaps = 40/340 (11%)
 Frame = +3

Query: 47  LADAVAVTMGPKGRTVIIEQSWGSPKVTKDGVTVAKSIDLKDKYKNIGAKLVQDVANNTN 106
           +A  +  ++GPKG   ++    G   VT DG T+   +D+  +     AKL+  ++ + +
Sbjct: 222 VASILKTSLGPKGLDKMMVSGDGDVTVTNDGATILDMMDVDHQI----AKLMVQLSKSQD 389

Query: 107 EEAGDGTTTATVLARSIAKEGFEKISKGANPVEIRRGVMLAVDAVIAELKKQSK----PV 162
           +E GDGTT   VLA ++ ++  + + +G +P+ I  G  +A    +  L K S      +
Sbjct: 390 DEIGDGTTGVVVLAGALLEQAEKLLDRGIHPIRIADGYEIAAKCAVETLDKISDNYEVDL 569

Query: 163 TTPEEIAQVATISANGDKDIGNIISDAMKKVGRKGVITVKDGKTLNDELEII-------- 214
              E + ++A ++  G K I N     M K+    +++V D K  + + E+I        
Sbjct: 570 KNAEPLIKLA-MTTLGSK-IVNRCHRQMAKIAVDAIMSVADLKRKDVDFELIKVEGKVGG 743

Query: 215 --------EGMKFDRGYISPYFINTSKGQK-----CEFQ---------------DAYVLL 246
                   +G+  D+    P      K  K     C F+               + Y  L
Sbjct: 744 KLEDTMLVKGVVVDKDMSHPQMPKVVKDAKIAILTCPFEPPKPKTKHKLDITSVEDYKKL 923

Query: 247 SEKKISSVQSIVPALEIANAHRKPLVIIAEDVDGEALSTLVLNRLKVGLQVVAVKAPGFG 306
            E +++  +S+V +++   A+   LVI     D EA      N L +  ++ AV+  G  
Sbjct: 924 REYELNKFESMVQSVKDKGAN---LVICQWGFDDEA------NHLLLQRELPAVRWVG-- 1070

Query: 307 DNRKNQLKDMAIATGGAVFGEEGLNLNLEDVQAHDLGKVG 346
                +++ +AIATGG +          E++    LGK G
Sbjct: 1071---GPEIELIAIATGGRIVP------RFEELTTEKLGKAG 1163
>29864
          Length = 1026

 Score = 42.4 bits (98), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 36/130 (27%), Positives = 63/130 (48%), Gaps = 1/130 (0%)
 Frame = +1

Query: 47  LADAVAVTMGPKGRTVIIEQSWGSPKVTKDGVTVAKSIDLKDKYKNIGAKLVQDVANNTN 106
           L D +   +GPKG   ++    G  K+TKDG  +   + +    ++  A L+  VA   +
Sbjct: 196 LQDVLRSNLGPKGTMKMLVSGAGDIKLTKDGNVLLHEMQI----QHPTASLIARVATAQD 363

Query: 107 EEAGDGTTTATVLARSIAKEGFEKISKGANPVEIRRGVMLAVDAVIAELKK-QSKPVTTP 165
           +  GDGTT+  ++   + K+    I++G +P  I  G  LA +  +  L++ + K     
Sbjct: 364 DITGDGTTSNVLIIGELLKQADLYIAEGLHPRLITEGFELARNKALEVLEEVKVKREVDR 543

Query: 166 EEIAQVATIS 175
           E + QVA  S
Sbjct: 544 ETLVQVARTS 573
>33770
          Length = 484

 Score = 42.0 bits (97), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 28/100 (28%), Positives = 49/100 (49%)
 Frame = +1

Query: 63  IIEQSWGSPKVTKDGVTVAKSIDLKDKYKNIGAKLVQDVANNTNEEAGDGTTTATVLARS 122
           +I+ + G   +T DG T+ K +    +  +  AK++ +++   + E GDGTTT  VLA S
Sbjct: 4   MIQAANGDVTITNDGATILKQM----QVLHPAAKMLVELSKAQDIEXGDGTTTVVVLAGS 171

Query: 123 IAKEGFEKISKGANPVEIRRGVMLAVDAVIAELKKQSKPV 162
           +     + ++KG +P  I      A    +  L    KP+
Sbjct: 172 LLDASAKLLAKGIHPTMISEAFQKAASKCVELLDGMVKPL 291
>21557
          Length = 1167

 Score = 31.2 bits (69), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 24/88 (27%), Positives = 40/88 (45%), Gaps = 13/88 (14%)
 Frame = +2

Query: 375 TEQLDITTSEY---------EKEKLNERLAKLSDGVAVLKVGGT--SDVEVNEKKDRVTD 423
           T Q D+    Y         ++++L + L +L+  V  L   GT      +NE +DR+  
Sbjct: 371 TNQFDMVVCAYTLLDQPGRQQRQQLVDDLWRLTSDVLXLVENGTFAGSSLINEARDRLLQ 550

Query: 424 ALNATRAAVEEGIVLGGGCALLR--CIP 449
           A N++    E+G V    C+L    C+P
Sbjct: 551 ASNSSENDTEKGYVF---CSLST**CLP 625
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|19527102|ref|NP_598648.1| syntaxin 12 [Mus musculus]
         (274 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

08305                                                                  54   5e-08
30761                                                                  53   1e-07
00045                                                                  30   1.6  
09530                                                                  28   2.7  
>08305
          Length = 1314

 Score = 54.3 bits (129), Expect = 5e-08,   Method: Compositional matrix adjust.
 Identities = 25/55 (45%), Positives = 36/55 (65%)
 Frame = -3

Query: 195 ILDVNQIFKDLAMMIHDQGDLIDSIEANVESSEVHVERATDQLQRAAYYQKKSRK 249
           + DVN +FK+L +M+  QG+ +DSIE N+E  EVHVE   +QL  A   Q K+ +
Sbjct: 583 VTDVNMLFKELNLMVSQQGEKLDSIEQNIEQVEVHVESGKEQLTEAVKSQXKAXR 419
>30761
          Length = 367

 Score = 52.8 bits (125), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 22/52 (42%), Positives = 38/52 (73%)
 Frame = +1

Query: 195 ILDVNQIFKDLAMMIHDQGDLIDSIEANVESSEVHVERATDQLQRAAYYQKK 246
           I+ VN+I+K+L  M+++QG  +DSIE+ VE + + V + TD L++A+ Y+ K
Sbjct: 190 IVGVNEIYKNLGAMVYEQGLTVDSIESQVEQTSIFVSQGTDNLRKASSYRVK 345
>00045
          Length = 1864

 Score = 29.6 bits (65), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 12/24 (50%), Positives = 14/24 (58%)
 Frame = -3

Query: 10  RNPGPSGPQPRDFNSIIQTCSGNI 33
           RNP PSG  P  FNS +    G+I
Sbjct: 857 RNPAPSGRYPSGFNSKLGNFMGDI 786
>09530
          Length = 971

 Score = 28.5 bits (62), Expect = 2.7,   Method: Compositional matrix adjust.
 Identities = 18/53 (33%), Positives = 29/53 (54%), Gaps = 7/53 (13%)
 Frame = -2

Query: 156 DSHEEWNQMQSQEEEAAI-TEQ------DLELIKERETAIRQLEADILDVNQI 201
           D H+E ++M  +  E  + TEQ      DL LIK  E +  ++E ++LDV  +
Sbjct: 391 DLHKEISEMLLEGVEVLVKTEQAFNKQFDLRLIKMGEGSFEEVEQEVLDVGHV 233
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|210147402|ref|NP_663482.2| aspartyl-tRNA synthetase
isoform 2 [Mus musculus]
         (87 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

14828                                                                  52   5e-08
>14828
          Length = 806

 Score = 52.4 bits (124), Expect = 5e-08,   Method: Compositional matrix adjust.
 Identities = 26/50 (52%), Positives = 36/50 (72%)
 Frame = -2

Query: 23  DYAKERYGISSMIQSQEKPDRVLVRVKDLTVQKADDVVWVRARVHTSRAK 72
           D ++ RYG   + QS+EK DRV+ +V +LT + AD  +WVRAR+H SRAK
Sbjct: 673 DVSEGRYGNLPLNQSREKLDRVIYKVCELTPKLADQKIWVRARLHVSRAK 524
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|47058962|ref|NP_081234.1| SRA stem-loop-interacting
RNA-binding protein [Mus musculus]
         (112 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

31618                                                                  52   5e-08
26197                                                                  50   2e-07
03406                                                                  50   2e-07
12350                                                                  50   3e-07
24983                                                                  49   5e-07
02415                                                                  47   2e-06
00302                                                                  45   6e-06
33516                                                                  42   4e-05
00817                                                                  39   5e-04
14258                                                                  39   6e-04
16016                                                                  39   7e-04
11019                                                                  38   8e-04
19868                                                                  37   0.002
05273                                                                  37   0.002
01937                                                                  37   0.003
14637                                                                  36   0.004
20488                                                                  35   0.008
03744                                                                  35   0.010
13038                                                                  34   0.013
15371                                                                  34   0.017
30672                                                                  33   0.022
04988                                                                  32   0.071
23720                                                                  32   0.071
23655                                                                  30   0.27 
35224                                                                  28   0.70 
10194                                                                  28   0.89 
25065                                                                  27   1.5  
17681                                                                  27   1.8  
05110                                                                  27   2.3  
20750                                                                  27   2.9  
18355                                                                  26   4.0  
00325                                                                  26   4.2  
00061                                                                  25   8.4  
10884                                                                  25   9.7  
>31618
          Length = 716

 Score = 52.4 bits (124), Expect = 5e-08,   Method: Compositional matrix adjust.
 Identities = 22/68 (32%), Positives = 35/68 (51%)
 Frame = +1

Query: 22  FVRKIPWTAAASELREHFAQFGHVRRCTVHFDKETGFHRGMGWVQFSSQEELQNALQQEH 81
           FV  + W     ELR+HF ++G +    V  D +TG  RG  ++ F++ E +      E 
Sbjct: 301 FVGGLSWETTEKELRDHFGKYGEIESINVKTDPQTGRSRGFAFIVFTNTEAIDQVSAAEE 480

Query: 82  HIIDGVKI 89
           HII+  K+
Sbjct: 481 HIINSKKV 504
>26197
          Length = 1365

 Score = 50.4 bits (119), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 23/68 (33%), Positives = 37/68 (54%)
 Frame = -2

Query: 22   FVRKIPWTAAASELREHFAQFGHVRRCTVHFDKETGFHRGMGWVQFSSQEELQNALQQEH 81
            FV  + W  ++  LRE+F +FG V  CT+  D ++G  RG G+V F     +   ++ + 
Sbjct: 1289 FVGGLSWETSSKHLREYFEKFGEVTSCTLKTDLDSGKSRGFGFVVFKEAVTVDAVVKNKE 1110

Query: 82   HIIDGVKI 89
            H + G KI
Sbjct: 1109 HKLQGRKI 1086

 Score = 37.4 bits (85), Expect = 0.001,   Method: Composition-based stats.
 Identities = 20/85 (23%), Positives = 41/85 (48%)
 Frame = -3

Query: 22   FVRKIPWTAAASELREHFAQFGHVRRCTVHFDKETGFHRGMGWVQFSSQEELQNALQQEH 81
            FV K+       ++  +FA+FG V    + +DK     R   +V+F + + ++  L+Q  
Sbjct: 1042 FVGKLDPGVPQEDVESYFAKFGKVVNVELPYDKVKDQRRAFCFVEFDNDKTVKKVLEQTS 863

Query: 82   HIIDGVKIHVQAQRAKALHGAQTSD 106
            H I G ++ +  +  K+  G+   +
Sbjct: 862  HKIGGQEVRIFKEILKSKEGSSMQE 788
>03406
          Length = 1292

 Score = 50.4 bits (119), Expect = 2e-07,   Method: Composition-based stats.
 Identities = 23/68 (33%), Positives = 36/68 (52%)
 Frame = +3

Query: 22  FVRKIPWTAAASELREHFAQFGHVRRCTVHFDKETGFHRGMGWVQFSSQEELQNALQQEH 81
           FV  + W   +  LRE+F +FG V  CT+  D ++G  RG G+V F     +   ++ + 
Sbjct: 249 FVGGLSWETXSKHLREYFEKFGEVTSCTLKTDLDSGKSRGFGFVVFKEAATVDAVVKNKE 428

Query: 82  HIIDGVKI 89
           H + G KI
Sbjct: 429 HKLQGRKI 452

 Score = 36.6 bits (83), Expect = 0.003,   Method: Composition-based stats.
 Identities = 19/71 (26%), Positives = 36/71 (50%)
 Frame = +3

Query: 22  FVRKIPWTAAASELREHFAQFGHVRRCTVHFDKETGFHRGMGWVQFSSQEELQNALQQEH 81
           FV K+       ++  +FA+FG V    + +DK     R   +V+F + + ++  L+Q  
Sbjct: 495 FVGKLDPGVPQEDVESYFAKFGKVVNVELPYDKVKDQRRAFCFVEFDNDKTVKKVLEQTS 674

Query: 82  HIIDGVKIHVQ 92
           H I G ++ V+
Sbjct: 675 HKIGGQEVDVK 707
>12350
          Length = 975

 Score = 49.7 bits (117), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 27/82 (32%), Positives = 43/82 (52%)
 Frame = -2

Query: 22  FVRKIPWTAAASELREHFAQFGHVRRCTVHFDKETGFHRGMGWVQFSSQEELQNALQQEH 81
            V  +PW +   +LR +F+QFG +    V  D +TG  +G G+++F+  E     + Q  
Sbjct: 611 IVLGLPWKSTEDDLRSYFSQFGDLLMVQVKKDPKTGQSKGFGFIRFAEYESQLKCMAQ-R 435

Query: 82  HIIDGVKIHVQAQRAKALHGAQ 103
           H+IDG    V+   +K   GAQ
Sbjct: 434 HMIDGRWCDVRIPNSK--EGAQ 375

 Score = 32.7 bits (73), Expect = 0.038,   Method: Compositional matrix adjust.
 Identities = 23/77 (29%), Positives = 34/77 (44%)
 Frame = -2

Query: 22  FVRKIPWTAAASELREHFAQFGHVRRCTVHFDKETGFHRGMGWVQFSSQEELQNALQQEH 81
           FV +      A +LR+ F++FG V    V   +     R   +V F+  E  Q +L  E 
Sbjct: 353 FVGRCTDDMTADDLRQFFSKFGEV--VDVFIPRP---FRAFAFVSFADPEVAQ-SLYGED 192

Query: 82  HIIDGVKIHVQAQRAKA 98
           HII G  +H+     K 
Sbjct: 191 HIIKGASVHISGAAPKP 141
>24983
          Length = 433

 Score = 48.9 bits (115), Expect = 5e-07,   Method: Compositional matrix adjust.
 Identities = 22/67 (32%), Positives = 35/67 (52%)
 Frame = -2

Query: 26  IPWTAAASELREHFAQFGHVRRCTVHFDKETGFHRGMGWVQFSSQEELQNALQQEHHIID 85
           +P+      LRE+F +FG +    V  D++TG  RG G+V  + +     A +  + IID
Sbjct: 294 LPYHTTDHSLREYFDKFGDIDEAVVITDRQTGKSRGYGFVTMADRTGADRACKDPNPIID 115

Query: 86  GVKIHVQ 92
           G K +V 
Sbjct: 114 GRKANVN 94
>02415
          Length = 2763

 Score = 47.0 bits (110), Expect = 2e-06,   Method: Composition-based stats.
 Identities = 24/70 (34%), Positives = 37/70 (52%)
 Frame = -1

Query: 22   FVRKIPWTAAASELREHFAQFGHVRRCTVHFDKETGFHRGMGWVQFSSQEELQNALQQEH 81
            FV  +P+      LRE+F +FG +    V  D++TG  RG G+V  + +     A +  +
Sbjct: 1917 FVGGLPYHTTDHSLREYFDKFGDIDEAVVITDRQTGKSRGYGFVTMADRTGADRACKDPN 1738

Query: 82   HIIDGVKIHV 91
             IIDG K +V
Sbjct: 1737 PIIDGRKANV 1708
>00302
          Length = 927

 Score = 45.4 bits (106), Expect = 6e-06,   Method: Compositional matrix adjust.
 Identities = 24/59 (40%), Positives = 34/59 (57%), Gaps = 1/59 (1%)
 Frame = -1

Query: 35  LREHFAQFGHVRRCTVHFDKETGFHRGMGWVQFSSQEELQNALQQEHHI-IDGVKIHVQ 92
           LRE F ++GH+    V +D++TG  RG  +V F S E+   A  + + I IDG KI V 
Sbjct: 417 LREVFGRYGHISEVQVVYDRQTGRSRGFAFVYFKSSEDAHEAKDRCNGIEIDGRKIRVD 241
>33516
          Length = 449

 Score = 42.4 bits (98), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 17/46 (36%), Positives = 26/46 (56%)
 Frame = +1

Query: 22  FVRKIPWTAAASELREHFAQFGHVRRCTVHFDKETGFHRGMGWVQF 67
           FV  + W      L+ +F+QFG +  C V  +++TG  RG G+V F
Sbjct: 163 FVGGLSWDTDQDSLQGYFSQFGEITDCIVMMNQQTGKSRGFGFVSF 300
>00817
          Length = 2606

 Score = 38.9 bits (89), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 19/66 (28%), Positives = 31/66 (46%)
 Frame = -2

Query: 27   PWTAAASELREHFAQFGHVRRCTVHFDKETGFHRGMGWVQFSSQEELQNALQQEHHIIDG 86
            P T  +S LR +F ++G +R C V  D  T   R   ++ F + E +    +   H IDG
Sbjct: 2524 PDTDESS-LRSYFEKYGDIRECIVVKDPATKRSRCFSFITFGNAENVDEVQKDRPHTIDG 2348

Query: 87   VKIHVQ 92
              +  +
Sbjct: 2347 RTVETK 2330
>14258
          Length = 1063

 Score = 38.5 bits (88), Expect = 6e-04,   Method: Compositional matrix adjust.
 Identities = 24/85 (28%), Positives = 40/85 (47%), Gaps = 11/85 (12%)
 Frame = +2

Query: 34  ELREHFAQFGHVRRCTVHFDKETGFHRGMGWVQFSSQEELQNALQQEHHIIDGVK-IHVQ 92
           +L + F  FG+V    V  DK+T   +  G+V + S    Q+A+   +    G+K + VQ
Sbjct: 107 DLMQMFMPFGNVISAKVFIDKQTNLSKCFGFVSYDSPMSAQDAISSMNGFQIGMKRLKVQ 286

Query: 93  AQRAK----------ALHGAQTSDE 107
            +R K          A  G+ +SD+
Sbjct: 287 LKRPKNDKPY*TSCLAXLGSASSDD 361
>16016
          Length = 1364

 Score = 38.5 bits (88), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 19/66 (28%), Positives = 31/66 (46%)
 Frame = -2

Query: 27   PWTAAASELREHFAQFGHVRRCTVHFDKETGFHRGMGWVQFSSQEELQNALQQEHHIIDG 86
            P T  +S LR +F ++G +R C V  D  T   R   ++ F + E +    +   H IDG
Sbjct: 1282 PDTDESS-LRSYFEKYGDIRECIVVKDPATKRSRCFSFITFGNAENVDEVQKDRPHTIDG 1106

Query: 87   VKIHVQ 92
              +  +
Sbjct: 1105 RTVETK 1088
>11019
          Length = 552

 Score = 38.1 bits (87), Expect = 8e-04,   Method: Compositional matrix adjust.
 Identities = 16/64 (25%), Positives = 31/64 (48%)
 Frame = -1

Query: 22  FVRKIPWTAAASELREHFAQFGHVRRCTVHFDKETGFHRGMGWVQFSSQEELQNALQQEH 81
           FV  +  +    +++ +F  +G +   T+ FDK T  HRG  +V F ++  +    +   
Sbjct: 225 FVGGLSSSTTVEDIKNYFKAYGTIEEATLMFDKVTSRHRGFAFVTFDNESTVDKVCEIHF 46

Query: 82  HIID 85
           H I+
Sbjct: 45  HEIN 34
>19868
          Length = 434

 Score = 37.4 bits (85), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 16/49 (32%), Positives = 26/49 (53%)
 Frame = +2

Query: 22  FVRKIPWTAAASELREHFAQFGHVRRCTVHFDKETGFHRGMGWVQFSSQ 70
           FV  +       +++ +F QFG +    + FDK+T  HRG G+V  S +
Sbjct: 275 FVGGLSAPTTLEDVKNYFEQFGPIEDAMLMFDKQTNRHRGFGFVTISKR 421
>05273
          Length = 1009

 Score = 36.6 bits (83), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 21/69 (30%), Positives = 31/69 (44%)
 Frame = -1

Query: 2   AASAIKGLSALRSSTGRPIAFVRKIPWTAAASELREHFAQFGHVRRCTVHFDKETGFHRG 61
           A +AI G SA+              P       LRE+F +FG +    V  D++TG  RG
Sbjct: 211 ATTAIPGSSAI-------------TPIITTDHSLREYFDKFGDIDEAVVITDRQTGKSRG 71

Query: 62  MGWVQFSSQ 70
            G+V  + +
Sbjct: 70  YGFVTMADR 44
>01937
          Length = 1320

 Score = 36.6 bits (83), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 14/58 (24%), Positives = 27/58 (46%)
 Frame = -1

Query: 22   FVRKIPWTAAASELREHFAQFGHVRRCTVHFDKETGFHRGMGWVQFSSQEELQNALQQ 79
            FV  +  +    + + +F  +G +   T+ FDK T  HRG  +V F ++  +    + 
Sbjct: 1206 FVGGLSSSTTVEDXKNYFKAYGTIEEATLMFDKVTSRHRGFAFVTFDNESTVDKVCEN 1033
>14637
          Length = 455

 Score = 35.8 bits (81), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 16/56 (28%), Positives = 27/56 (48%)
 Frame = -1

Query: 22  FVRKIPWTAAASELREHFAQFGHVRRCTVHFDKETGFHRGMGWVQFSSQEELQNAL 77
           F+  +P      +L + F  FG+V    V  DK+T   +  G+V + S    Q+A+
Sbjct: 194 FIYHLPQEFGDQDLMQMFMPFGNVISAKVFIDKQTNLSKCFGFVSYDSPMSAQDAI 27
>20488
          Length = 3281

 Score = 34.7 bits (78), Expect = 0.008,   Method: Composition-based stats.
 Identities = 22/77 (28%), Positives = 37/77 (48%), Gaps = 1/77 (1%)
 Frame = +2

Query: 22   FVRKIPWTAAASELREHFAQFGHVRRCTVHFDKETGFHRGMGWVQFSSQEELQNALQQEH 81
            F+  +P      +L + F  FG+V    V  DK+T   +  G+V + S    Q A+   +
Sbjct: 2717 FIYHLPQEFGDQDLMQMFMPFGNVVSAKVFIDKQTNLSKCFGFVSYDSPLAAQAAITSMN 2896

Query: 82   HIIDGVK-IHVQAQRAK 97
                G+K + VQ +R+K
Sbjct: 2897 GFQIGMKRLKVQLKRSK 2947
>03744
          Length = 3486

 Score = 34.7 bits (78), Expect = 0.010,   Method: Composition-based stats.
 Identities = 22/77 (28%), Positives = 37/77 (48%), Gaps = 1/77 (1%)
 Frame = -1

Query: 22   FVRKIPWTAAASELREHFAQFGHVRRCTVHFDKETGFHRGMGWVQFSSQEELQNALQQEH 81
            F+  +P      +L + F  FG+V    V  DK+T   +  G+V + S    Q A+   +
Sbjct: 3207 FIYHLPQEFGDQDLMQMFMPFGNVVSAKVFIDKQTNLSKCFGFVSYDSPLAAQAAITSMN 3028

Query: 82   HIIDGVK-IHVQAQRAK 97
                G+K + VQ +R+K
Sbjct: 3027 GFQIGMKRLKVQLKRSK 2977
>13038
          Length = 987

 Score = 34.3 bits (77), Expect = 0.013,   Method: Compositional matrix adjust.
 Identities = 18/67 (26%), Positives = 34/67 (50%), Gaps = 3/67 (4%)
 Frame = +2

Query: 41  QFGHVRRCTVHFD---KETGFHRGMGWVQFSSQEELQNALQQEHHIIDGVKIHVQAQRAK 97
           ++ ++  C +++    ++ G   GMG++Q  + E   N   Q H+ I  VKI++   +  
Sbjct: 380 KYLYINNCNIYYTNNCRDCGPSSGMGFLQKKTSET*GN---QSHNPIKTVKIYIHCVQTA 550

Query: 98  ALHGAQT 104
            LH A T
Sbjct: 551 VLHSACT 571
>15371
          Length = 383

 Score = 33.9 bits (76), Expect = 0.017,   Method: Compositional matrix adjust.
 Identities = 14/48 (29%), Positives = 23/48 (47%)
 Frame = -2

Query: 22  FVRKIPWTAAASELREHFAQFGHVRRCTVHFDKETGFHRGMGWVQFSS 69
           F+  +P      +L + F  FG+V    V  DK+T   +  G+V + S
Sbjct: 148 FIYHLPQEFGDQDLMQMFMPFGNVVSAKVFIDKQTNLSKCFGFVSYDS 5
>30672
          Length = 877

 Score = 33.5 bits (75), Expect = 0.022,   Method: Compositional matrix adjust.
 Identities = 15/56 (26%), Positives = 29/56 (51%)
 Frame = +3

Query: 22  FVRKIPWTAAASELREHFAQFGHVRRCTVHFDKETGFHRGMGWVQFSSQEELQNAL 77
            +R + +    +++R HF +FG +   T+   K+    RG  +VQF+  +  Q A+
Sbjct: 414 IIRNLAFKCKEADIRSHFGKFGTISEVTIPL-KQGDRSRGFAFVQFTEVKAAQKAI 578
>04988
          Length = 705

 Score = 31.6 bits (70), Expect = 0.071,   Method: Compositional matrix adjust.
 Identities = 19/65 (29%), Positives = 34/65 (52%), Gaps = 1/65 (1%)
 Frame = -3

Query: 34  ELREHFAQFGHVRRCTVHFDKETGFHRGMGWVQFSSQEELQNALQQ-EHHIIDGVKIHVQ 92
           +L+++  Q G V     H       HR  G ++F++  +L+NAL + ++  I+G KI + 
Sbjct: 253 DLKDYMRQAGEVTYADAH-----KRHRNEGIIEFATSSDLKNALDKLDNTEINGRKIKLV 89

Query: 93  AQRAK 97
             R K
Sbjct: 88  EDRPK 74
>23720
          Length = 739

 Score = 31.6 bits (70), Expect = 0.071,   Method: Compositional matrix adjust.
 Identities = 19/65 (29%), Positives = 34/65 (52%), Gaps = 1/65 (1%)
 Frame = -1

Query: 34  ELREHFAQFGHVRRCTVHFDKETGFHRGMGWVQFSSQEELQNALQQ-EHHIIDGVKIHVQ 92
           +L+++  Q G V     H       HR  G ++F++  +L+NAL + ++  I+G KI + 
Sbjct: 295 DLKDYMRQAGEVTYADAH-----KRHRNEGIIEFATSSDLKNALDKLDNTEINGRKIKLV 131

Query: 93  AQRAK 97
             R K
Sbjct: 130 EDRPK 116
>23655
          Length = 929

 Score = 29.6 bits (65), Expect = 0.27,   Method: Compositional matrix adjust.
 Identities = 16/50 (32%), Positives = 24/50 (48%)
 Frame = -1

Query: 11  ALRSSTGRPIAFVRKIPWTAAASELREHFAQFGHVRRCTVHFDKETGFHR 60
            +RSST R   FV  +        +R+ F +FG +    +  DK TG +R
Sbjct: 929 PIRSSTVREKMFVGGVKEDTTEDMIRDTFNEFGEITGVDLIQDKGTGKNR 780
>35224
          Length = 432

 Score = 28.5 bits (62), Expect = 0.70,   Method: Compositional matrix adjust.
 Identities = 13/38 (34%), Positives = 24/38 (63%), Gaps = 1/38 (2%)
 Frame = -2

Query: 59  HRGMGWVQFSSQEELQNALQQ-EHHIIDGVKIHVQAQR 95
           HR  G ++F++  +L+NAL + ++  I+G KI +   R
Sbjct: 413 HRNEGIIEFATSSDLKNALDKLDNTEINGRKIKLVEDR 300
>10194
          Length = 1278

 Score = 28.1 bits (61), Expect = 0.89,   Method: Composition-based stats.
 Identities = 24/101 (23%), Positives = 38/101 (37%), Gaps = 17/101 (16%)
 Frame = -3

Query: 12  LRSSTGRPIAFVRKIPWTAAASELREHFAQFGHVR----RCTVHFDKET---------GF 58
           L+ +  +   FV  +P      +L   F QFG +     RC    D  T          F
Sbjct: 733 LQRANEKRTVFVGNVPLKTDKKKLARLFKQFGKIENVRFRCAPVGDPTTKKRVAVITKDF 554

Query: 59  HRGM----GWVQFSSQEELQNALQQEHHIIDGVKIHVQAQR 95
           H        ++ F   E  + AL    H+IDG+ + V + +
Sbjct: 553 HEKRHNISAYICFKEDEAAKQALTLNGHVIDGLHLRVDSAK 431
>25065
          Length = 632

 Score = 27.3 bits (59), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 18/54 (33%), Positives = 26/54 (48%), Gaps = 9/54 (16%)
 Frame = -2

Query: 66  QFSSQEELQNALQQEH-----HIIDGVKIHVQAQRAKALHGAQTS----DEERF 110
           Q   +E+L N L + H     HII  ++I ++ QR   LHG        D+ RF
Sbjct: 244 QRKGEEDLHNFLLRHHKFAVLHIIFTLRISLRGQRKHILHGVSMCLKMLDQNRF 83
>17681
          Length = 964

 Score = 26.9 bits (58), Expect = 1.8,   Method: Compositional matrix adjust.
 Identities = 18/70 (25%), Positives = 31/70 (44%), Gaps = 1/70 (1%)
 Frame = +2

Query: 13  RSSTGRPIAFVRKIPWTAAASELR-EHFAQFGHVRRCTVHFDKETGFHRGMGWVQFSSQE 71
           +SS      +    P    + EL  +HF QFG ++   V  DK      G  +++F ++E
Sbjct: 404 QSSPTNTTVYCGGFPPNVISDELMHKHFMQFGPIQDVRVFKDK------GFAFIKFVTKE 565

Query: 72  ELQNALQQEH 81
               A++  H
Sbjct: 566 AAARAIEHTH 595
>05110
          Length = 475

 Score = 26.9 bits (58), Expect = 2.3,   Method: Compositional matrix adjust.
 Identities = 12/23 (52%), Positives = 14/23 (60%)
 Frame = -3

Query: 60  RGMGWVQFSSQEELQNALQQEHH 82
           R  GWV   S+  LQNALQ+  H
Sbjct: 245 RPNGWVLCQSESRLQNALQKTQH 177
>20750
          Length = 541

 Score = 26.6 bits (57), Expect = 2.9,   Method: Compositional matrix adjust.
 Identities = 12/31 (38%), Positives = 16/31 (51%)
 Frame = +3

Query: 52  FDKETGFHRGMGWVQFSSQEELQNALQQEHH 82
           F   T F RG GWV   +   L + ++Q HH
Sbjct: 138 FFVSTLFARGQGWVTLQTGRGLSSKVEQSHH 230
>18355
          Length = 1341

 Score = 25.8 bits (55), Expect = 4.0,   Method: Composition-based stats.
 Identities = 12/23 (52%), Positives = 14/23 (60%)
 Frame = +3

Query: 60  RGMGWVQFSSQEELQNALQQEHH 82
           R  GWV   S+  LQNALQ+  H
Sbjct: 804 RPNGWVLCKSESRLQNALQKTQH 872
>00325
          Length = 435

 Score = 25.8 bits (55), Expect = 4.2,   Method: Compositional matrix adjust.
 Identities = 11/26 (42%), Positives = 14/26 (53%)
 Frame = -1

Query: 79  QEHHIIDGVKIHVQAQRAKALHGAQT 104
           Q H+ I  VKI++   R   LH A T
Sbjct: 252 QSHNPIKNVKIYIHCVRTAVLHSACT 175
>00061
          Length = 429

 Score = 25.0 bits (53), Expect = 8.4,   Method: Compositional matrix adjust.
 Identities = 21/89 (23%), Positives = 35/89 (39%), Gaps = 4/89 (4%)
 Frame = -1

Query: 20  IAFVRKIPWTAAASEL---REHFAQFGHVRRCT-VHFDKETGFHRGMGWVQFSSQEELQN 75
           + F   I +T           HF  + H+     ++    T    GMG++Q   ++    
Sbjct: 417 VYFFLSIIYTNTTCMYTTGESHFHTYIHINTSEHIYITYTTNHLSGMGFLQ---KKNS*T 247

Query: 76  ALQQEHHIIDGVKIHVQAQRAKALHGAQT 104
              Q H+ I  VKI++   +   LH A T
Sbjct: 246 *GDQSHNPIKNVKIYIHCVQTAVLHSACT 160
>10884
          Length = 1555

 Score = 24.6 bits (52), Expect = 9.7,   Method: Compositional matrix adjust.
 Identities = 12/27 (44%), Positives = 15/27 (55%), Gaps = 7/27 (25%)
 Frame = -2

Query: 16   TGRPIAF-------VRKIPWTAAASEL 35
            TGRP+ +       V K PWT  ASE+
Sbjct: 1248 TGRPLNYREIFSTHVLKFPWTRTASEI 1168
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|165932348|ref|NP_444475.2| aryl hydrocarbon
receptor-interacting protein-like 1 [Mus musculus]
         (328 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

00888                                                                  54   8e-08
13560                                                                  39   0.004
35341                                                                  31   0.66 
03349                                                                  28   5.1  
>00888
          Length = 970

 Score = 53.9 bits (128), Expect = 8e-08,   Method: Compositional matrix adjust.
 Identities = 37/154 (24%), Positives = 70/154 (45%)
 Frame = -3

Query: 147 LVFLIELLQVEAPNEYQRETWNLNNEERMQAVPLLHGEGNRLYKLGRYDQAATKYQEAIV 206
           LV+ +E++  E      +++W ++  E+++   ++  +G   +K G+Y +A T Y++ + 
Sbjct: 821 LVYNVEMVNFEKA----KQSWEMDVGEKIEQSKIIKEKGTAAFKKGKYQRALTNYEKIVS 654

Query: 207 CLRNLQTKEKPWEVEWLKLEKMINTLILNYCQCXXXXXXXXXXXXHTSDILRHHPGIVKA 266
            L +  T     E+      +++    LN   C              + +L      VKA
Sbjct: 653 FLEHESTGLSDSELS--DKHQLMVAAFLNIAMCQLKLLDYRQAEETCNKVLAMSTNNVKA 480

Query: 267 YYMRARAHAEVWNAEEAKADLEKVLELEPSMRKA 300
            + R +A  E  +  EA +D  KVLELEP  + A
Sbjct: 479 LFRRGQARLECADYTEAASDFSKVLELEPGNKAA 378
>13560
          Length = 978

 Score = 38.5 bits (88), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 34/133 (25%), Positives = 53/133 (39%), Gaps = 1/133 (0%)
 Frame = +1

Query: 167 WNLNNEERMQAVPLLHGEGNRLYKLGRYDQAATKYQEAI-VCLRNLQTKEKPWEVEWLKL 225
           W L   E+  +  +   +G + +K G    A + ++ AI + L  L       EV     
Sbjct: 157 WRLTPLEKYSSASVHKEKGAQYFKTGNIFAAFSHFRTAIRLLLSVLPYSFSDDEVASTSH 336

Query: 226 EKMINTLILNYCQCXXXXXXXXXXXXHTSDILRHHPGIVKAYYMRARAHAEVWNAEEAKA 285
            +++    LN   C            + +  L   P  VKA Y RA A+  + N   A  
Sbjct: 337 LQLLCQCYLNLAACQIKSGHHKHVITNCTHALNLDPANVKALYRRASANVNLGNLLHAHE 516

Query: 286 DLEKVLELEPSMR 298
           DLE  L+ EP+ R
Sbjct: 517 DLETGLQKEPNNR 555
>35341
          Length = 641

 Score = 31.2 bits (69), Expect = 0.66,   Method: Compositional matrix adjust.
 Identities = 17/40 (42%), Positives = 24/40 (60%)
 Frame = +3

Query: 261 PGIVKAYYMRARAHAEVWNAEEAKADLEKVLELEPSMRKA 300
           P  VKAY  RA A   +   + A  D E+VL+LEP+ ++A
Sbjct: 117 PLYVKAYLRRAAARVGMQRLQPALEDYERVLQLEPNSKQA 236
>03349
          Length = 1686

 Score = 28.1 bits (61), Expect = 5.1,   Method: Compositional matrix adjust.
 Identities = 11/54 (20%), Positives = 27/54 (50%)
 Frame = -3

Query: 160  NEYQRETWNLNNEERMQAVPLLHGEGNRLYKLGRYDQAATKYQEAIVCLRNLQT 213
             E   +   + N  +++ + +L+G      ++GRYD     ++  + C+R ++T
Sbjct: 1039 TECDSDIXKIQNHSQIEKISVLYG------RVGRYDTGLPSFRATMHCIRQIKT 896
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|26986553|ref|NP_758467.1| phosphodiesterase 8B [Mus
musculus]
         (730 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

19664                                                                  55   8e-08
28167                                                                  49   5e-06
28476                                                                  32   0.83 
03567                                                                  32   1.1  
26095                                                                  29   5.6  
35756                                                                  29   5.6  
>19664
          Length = 420

 Score = 55.5 bits (132), Expect = 8e-08,   Method: Composition-based stats.
 Identities = 23/49 (46%), Positives = 30/49 (61%)
 Frame = +1

Query: 676 KSQISFIDYFITDMFDAWDAFAHLPALMQHLADNYKHWKTLDDLKCKTL 724
           KSQI FI+Y I DM +AWD+F  +P L+  +  NY  WK  D+    TL
Sbjct: 1   KSQIGFIEYIIQDMMEAWDSFIDMPQLITCMKINYAQWKKYDEQGVNTL 147
>28167
          Length = 587

 Score = 49.3 bits (116), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 39/146 (26%), Positives = 66/146 (45%), Gaps = 2/146 (1%)
 Frame = +2

Query: 570 LATEMTKHFEHVNKFVNSINKPLAAESEGSDCECNPTGKNFPENQILIKRMMIKCADVAN 629
           LAT++  +F +  +F +    P    S+  DC           N+ L++ MM+  +DVA 
Sbjct: 2   LATDLALYFRYRGRFFDLTKSPEVNWSD--DC-----------NRDLLRSMMMTASDVAA 142

Query: 630 PCRPLDLCIEWAGRISEEYFAQTDEEKRQGLPVVMPVFDRNTC-SIPKSQISFIDYFITD 688
             +P ++  + A  +S E+F Q D EK       M + DR     +P  Q+ FID     
Sbjct: 143 ITKPWEVQKKVAHLVSREFFEQGDMEKETLKIQPMEMMDREKKDKLPNMQVGFIDTICLP 322

Query: 689 MFDAWDAFA-HLPALMQHLADNYKHW 713
           +++A    +  L  L++    N  HW
Sbjct: 323 VYEAMTRVSPRLSPLLKGCQQNRDHW 400
>28476
          Length = 1475

 Score = 32.0 bits (71), Expect = 0.83,   Method: Compositional matrix adjust.
 Identities = 15/51 (29%), Positives = 21/51 (41%)
 Frame = -3

Query: 424 KVFSRFGVCEFLNCTETTLRAWLQVIEANYHSSNAYHNSTHAADVLHATAF 474
           K+F+  G+ E           +   +E  Y     YHN  HA DVLH   +
Sbjct: 183 KLFTEVGLMETFRIPVVEFINYFHALELGY-REKPYHNRVHATDVLHGVYY 34
>03567
          Length = 1390

 Score = 31.6 bits (70), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 17/39 (43%), Positives = 21/39 (53%), Gaps = 1/39 (2%)
 Frame = +2

Query: 17  IGPMRLTQDPIQVLLIFAKEDSQS-DGFWWACDRAGYRC 54
           +GP+ LT      L +   ED QS  GFW   +R GYRC
Sbjct: 521 LGPLPLT------LYLDGLEDPQSFAGFWLTLNRFGYRC 619
>26095
          Length = 685

 Score = 29.3 bits (64), Expect = 5.6,   Method: Composition-based stats.
 Identities = 14/39 (35%), Positives = 18/39 (46%)
 Frame = -3

Query: 596 SEGSDCECNPTGKNFPENQILIKRMMIKCADVANPCRPL 634
           S  S C  NP    +PEN  L+K     C  V   C+P+
Sbjct: 680 STWSACLWNPPHNTWPENSTLLKERRGDCTGVWITCQPM 564
>35756
          Length = 368

 Score = 29.3 bits (64), Expect = 5.6,   Method: Composition-based stats.
 Identities = 13/43 (30%), Positives = 20/43 (46%)
 Frame = -1

Query: 52  YRCNIARTPESALECFLDKHHEIIVIDHRQSRNFDAEAVCRSI 94
           ++C   RT ++     + K HEI  I H   R F  +  C +I
Sbjct: 332 WKCRSIRTEQTGFRVSMGKQHEISQIFHFLQRGFKIQVQCNAI 204
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|22122457|ref|NP_666111.1| ras homolog gene family,
member T2 [Mus musculus]
         (620 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

19006                                                                  55   9e-08
11728                                                                  47   3e-05
08428                                                                  42   5e-04
10708                                                                  42   7e-04
26083                                                                  42   7e-04
34468                                                                  37   0.019
17511                                                                  37   0.025
18443                                                                  36   0.037
31291                                                                  35   0.061
09700                                                                  33   0.32 
04230                                                                  32   0.51 
03732                                                                  32   0.61 
33374                                                                  31   1.5  
27864                                                                  31   1.8  
00825                                                                  30   2.1  
18208                                                                  30   4.0  
36867                                                                  29   5.3  
09123                                                                  29   6.4  
>19006
          Length = 568

 Score = 55.1 bits (131), Expect = 9e-08,   Method: Compositional matrix adjust.
 Identities = 40/149 (26%), Positives = 68/149 (45%), Gaps = 1/149 (0%)
 Frame = -2

Query: 6   RILLLGEAQVGKTSLILSLVGEEFPE-EVPARAEEITIPADVTPEKVPTHIVDYSXXXXX 64
           +++++G+   GKT L++    ++FPE  VP   E      +V  ++V   + D +     
Sbjct: 432 KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDSKQVELALWDTAGQEDY 253

Query: 65  XXXXXXXIHKANVVCVVYDVSEETTIEKIRTKWIPLVNGRTATGPRLPIILVGNKSDLRP 124
                      +V+ + + +    ++E I  KW P V       P +PIILVGNK DLR 
Sbjct: 252 DRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVRH---FCPNVPIILVGNKKDLRN 82

Query: 125 GSTMEAVLPIMSQFPEIETCVECSAKHLR 153
               +  L  M Q P     ++  A+H+R
Sbjct: 81  DENTKRELMKMKQEP---VRLDRRARHVR 4
>11728
          Length = 635

 Score = 46.6 bits (109), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 30/120 (25%), Positives = 54/120 (45%), Gaps = 1/120 (0%)
 Frame = -1

Query: 5   VRILLLGEAQVGKTSLILSLVGEEFPEE-VPARAEEITIPADVTPEKVPTHIVDYSXXXX 63
           ++ +++G+  VGKT L++S     FP E +P   +  +    V  + +   + D +    
Sbjct: 488 IKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDSKPINLGLWDTAGQED 309

Query: 64  XXXXXXXXIHKANVVCVVYDVSEETTIEKIRTKWIPLVNGRTATGPRLPIILVGNKSDLR 123
                     + +V  + + +    + E ++ KW P V+      P  PIILVG K DLR
Sbjct: 308 YDRLRPLSYPQTDVFLICFSLISPASFENVKAKWYPEVSHHC---PNTPIILVGTKLDLR 138
>08428
          Length = 1109

 Score = 42.4 bits (98), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 43/167 (25%), Positives = 72/167 (43%), Gaps = 10/167 (5%)
 Frame = -3

Query: 3    RDVRILLLGEAQVGKTSLILSLV-GEEFPEEVPARAEEITIPADVTPEKVPT-------H 54
            RDV++ LLG++ VGK+S++L  V G   P      ++E TI A    + +          
Sbjct: 1074 RDVKVCLLGDSGVGKSSIVLRFVTGSYRP------SQESTIGASFMSKSLVVDGAGYRFQ 913

Query: 55   IVDYSXXXXXXXXXXXXIHKANVVCVVYDVSEETTIEKIRTKWIPLVNGRTATGPRLPII 114
            I D +               A    +VYDV+   T + +++ WI  +  R+   P + + 
Sbjct: 912  IWDTAGQEKFRALAPMYYRGAAAAVIVYDVTRPRTFKSVKS-WIQEL--RSFGPPNIVLA 742

Query: 115  LVGNKSDLRPGSTMEAVLPIMSQFPEIETCV--ECSAKHLRNISELF 159
            + GNK DL      E V     ++    + +  E SA    N+ E+F
Sbjct: 741  IAGNKCDLE--ELREVVEKDAQEYASSISAIFGETSAMTAVNVEEMF 607
>10708
          Length = 2775

 Score = 42.0 bits (97), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 30/86 (34%), Positives = 37/86 (43%), Gaps = 13/86 (15%)
 Frame = -3

Query: 96   KWIPLVNGRTATGPRLPIILVGNKSDLRPGSTMEAVLPIMSQFP-------------EIE 142
            KW P V       P +PIILVGNK DLR     +  L  M Q P                
Sbjct: 2587 KWTPEVRH---FCPNVPIILVGNKKDLRNDENTKRELMKMKQEPVRLDEGRAMSEKINAY 2417

Query: 143  TCVECSAKHLRNISELFYYAQKAVLH 168
            + +ECSAK    + E+F  A +A L 
Sbjct: 2416 SYLECSAKTKEGVREVFETATRAALQ 2339
>26083
          Length = 432

 Score = 42.0 bits (97), Expect = 7e-04,   Method: Composition-based stats.
 Identities = 36/124 (29%), Positives = 54/124 (43%), Gaps = 7/124 (5%)
 Frame = +1

Query: 3   RDVRILLLGEAQVGKTSLILSLVGEEFPEEVPARAEEITIPAD-------VTPEKVPTHI 55
           R  +++ LGE  VGKTSLI   + + F     A     TI  D       +    +   +
Sbjct: 73  RKFKLVFLGEQSVGKTSLITRFMYDSFDNTYQA-----TIGIDFLSKTMYLEDRTIRLQL 237

Query: 56  VDYSXXXXXXXXXXXXIHKANVVCVVYDVSEETTIEKIRTKWIPLVNGRTATGPRLPIIL 115
            D +            I  ++V  VVYD++   +  +  +KWI  V  RT  G  + I+L
Sbjct: 238 WDTAGQERFRSLIPSYIRDSSVAVVVYDITNANSFHQT-SKWIDDV--RTERGSDVIIML 408

Query: 116 VGNK 119
           VGNK
Sbjct: 409 VGNK 420
>34468
          Length = 1502

 Score = 37.4 bits (85), Expect = 0.019,   Method: Compositional matrix adjust.
 Identities = 34/129 (26%), Positives = 58/129 (44%), Gaps = 8/129 (6%)
 Frame = +1

Query: 2   RRDVRILLLGEAQVGKTSLILSLVGEEFPEEVPARAEEITIPAD-------VTPEKVPTH 54
           RR  +I+++G++ VGKT L       +FP++  A     TI  D       V  E +   
Sbjct: 487 RRIFKIIVIGDSNVGKTCLTYRFCLGKFPDKTEA-----TIGVDFREKSIQVDSEHLKLQ 651

Query: 55  IVDYSXXXXXXXXXXXXIHK-ANVVCVVYDVSEETTIEKIRTKWIPLVNGRTATGPRLPI 113
           + D +             ++  + V  VYD+++ ++ E +   WI   +    T   +P 
Sbjct: 652 LWDTAGQERFRKSMVQHYYRNVHAVVFVYDMTKMSSFENM-PAWIEECDRHNLT-KYIPR 825

Query: 114 ILVGNKSDL 122
           ILVGNK D+
Sbjct: 826 ILVGNKCDV 852
>17511
          Length = 483

 Score = 37.0 bits (84), Expect = 0.025,   Method: Composition-based stats.
 Identities = 30/122 (24%), Positives = 54/122 (44%), Gaps = 4/122 (3%)
 Frame = -3

Query: 5   VRILLLGEAQVGKTSLILSLVGEEFPEEVPAR--AEEITIPADVTPEKVPTHIVDYSXXX 62
           +++++LG++ VGKTSL+   V ++F  +  A   A+ +T    V    V   I D +   
Sbjct: 364 LKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQIWDTAGQE 185

Query: 63  XXXXXXXXXIHKANVVCVVYDVSEETTIEKIRTKWIP--LVNGRTATGPRLPIILVGNKS 120
                       A+   +V+DV+   T   + + W    L+          P +++GNK 
Sbjct: 184 RFQSLGVAFYRGADCCVLVFDVTMPNTFRSLDS-WRDEFLIQASPRDPENFPFVVIGNKI 8

Query: 121 DL 122
           DL
Sbjct: 7   DL 2
>18443
          Length = 945

 Score = 36.2 bits (82), Expect = 0.037,   Method: Compositional matrix adjust.
 Identities = 25/76 (32%), Positives = 36/76 (47%), Gaps = 1/76 (1%)
 Frame = -2

Query: 236 NVSGGVQNDRLTLEGFLFLNTLFIQRGRHETTWTILRRFGYSDSL-ELTPDYLYPALHVP 294
            +S G  N+R  L  F F+   F   GR  TTW + R    S +L    P +L+P   VP
Sbjct: 587 TLSTGHANERGVLFHFFFVTASFSWSGRLRTTWPLCR---ASRALCSHPPCHLHPLFQVP 417

Query: 295 PGCSTELNHRGYQFVQ 310
           PG  ++ +    + VQ
Sbjct: 416 PGGHSDWHQVWERSVQ 369
>31291
          Length = 446

 Score = 35.4 bits (80), Expect = 0.061,   Method: Compositional matrix adjust.
 Identities = 27/99 (27%), Positives = 44/99 (44%), Gaps = 15/99 (15%)
 Frame = -1

Query: 76  NVVCVVYDVSEETTIEKIRTKWIPLVNGRTATGPRLPIILVGNKSDLRPGSTMEAVLPIM 135
           +V  + + +  E +++ ++ KW P +       P +PI+LVG K DLR     EAV  + 
Sbjct: 377 DVFMLXFSLMSEASMKNVKVKWYPEIRHH---DPHVPIVLVGTKLDLRQDK--EAVRKLR 213

Query: 136 S--QFP-------------EIETCVECSAKHLRNISELF 159
           S  Q P             + +   ECS+K   N+   F
Sbjct: 212 SSRQDPVSSNQGNDLAKAIKAKRYFECSSKTQENLKTAF 96
>09700
          Length = 1855

 Score = 33.1 bits (74), Expect = 0.32,   Method: Compositional matrix adjust.
 Identities = 21/65 (32%), Positives = 30/65 (46%), Gaps = 12/65 (18%)
 Frame = -1

Query: 107  TGPRLPIILVGNKSDLRPGSTMEAVLPIMSQFPEIE------------TCVECSAKHLRN 154
              PR P++LVG +SDLR    +   L    + P  E            + VECSA   +N
Sbjct: 1828 NSPRTPLVLVGTQSDLRNDVKVLIELAKYKEKPVSEDDASKLAHQLGASYVECSALTQKN 1649

Query: 155  ISELF 159
            + E+F
Sbjct: 1648 LKEMF 1634
>04230
          Length = 1190

 Score = 32.3 bits (72), Expect = 0.51,   Method: Compositional matrix adjust.
 Identities = 15/41 (36%), Positives = 19/41 (46%)
 Frame = -1

Query: 256  TLFIQRGRHETTWTILRRFGYSDSLELTPDYLYPALHVPPG 296
            TL I R R    W  +RRF     L +  D+LY    + PG
Sbjct: 1172 TLCITRDRSACVWNNVRRFSNFQKLLMMNDFLYNKQGMKPG 1050
>03732
          Length = 1114

 Score = 32.3 bits (72), Expect = 0.61,   Method: Compositional matrix adjust.
 Identities = 19/76 (25%), Positives = 33/76 (43%), Gaps = 5/76 (6%)
 Frame = -1

Query: 307  QFVQRMFEKHDQDHDGVLSPTELQNLFSVFSGAPWGPELLHTV-----PTQAGCLPLHGY 361
             F+  +F++ D+D  G +S  ELQ   S  +  P+ PE +  +        +G +    +
Sbjct: 1102 NFLAGIFQRIDKDRSGNISVNELQQALSNGTWTPFNPETVRLMIGMFDRDNSGTINFQEF 923

Query: 362  LCQWTLMTYLDVQQCL 377
               W  +T  D Q C 
Sbjct: 922  QALWKYVT--DWQNCF 881
>33374
          Length = 489

 Score = 30.8 bits (68), Expect = 1.5,   Method: Composition-based stats.
 Identities = 13/26 (50%), Positives = 20/26 (76%)
 Frame = +2

Query: 6  RILLLGEAQVGKTSLILSLVGEEFPE 31
          +++LLGE+ VGK+SL+L  V  +F E
Sbjct: 35 KLVLLGESAVGKSSLVLRFVKGQFHE 112
>27864
          Length = 343

 Score = 30.8 bits (68), Expect = 1.8,   Method: Composition-based stats.
 Identities = 19/75 (25%), Positives = 33/75 (44%), Gaps = 5/75 (6%)
 Frame = +1

Query: 308 FVQRMFEKHDQDHDGVLSPTELQNLFSVFSGAPWGPELLHTV-----PTQAGCLPLHGYL 362
           F+  +F++ D+D  G +S  ELQ   S  +  P+ PE +  +        +G +    + 
Sbjct: 16  FLAGIFQRIDKDRSGNISVNELQQALSNGTWTPFNPETVRLMIGMFDRDNSGTINFQEFQ 195

Query: 363 CQWTLMTYLDVQQCL 377
             W  +T  D Q C 
Sbjct: 196 ALWKYVT--DWQNCF 234
>00825
          Length = 1821

 Score = 30.4 bits (67), Expect = 2.1,   Method: Compositional matrix adjust.
 Identities = 29/103 (28%), Positives = 48/103 (46%), Gaps = 2/103 (1%)
 Frame = +3

Query: 281  ELTPDYLYPALHVPPGCSTELN-HRGYQFVQRMFEKHDQDHDGVLSPTELQNL-FSVFSG 338
            E + D +  + H  P C T ++ H G   +    ++H Q        T ++ +  ++F G
Sbjct: 1146 EDSDDLVVASRHKLPPCGTVVHIHHGSCVISVHVQRHAQ-------FTHVKRVQVAIFIG 1304

Query: 339  APWGPELLHTVPTQAGCLPLHGYLCQWTLMTYLDVQQCLAHLG 381
              +  E  H VP Q     LH YL QW+  +++ VQQ  A +G
Sbjct: 1305 RGY-CEGFHRVPRQRIGAHLHDYLSQWSXSSHV-VQQNAAVMG 1427
>18208
          Length = 458

 Score = 29.6 bits (65), Expect = 4.0,   Method: Composition-based stats.
 Identities = 15/38 (39%), Positives = 21/38 (55%)
 Frame = -1

Query: 3   RDVRILLLGEAQVGKTSLILSLVGEEFPEEVPARAEEI 40
           R++RILLLG    GKT+L+  L  E+     P +   I
Sbjct: 305 RELRILLLGLDNAGKTTLLKQLASEDPSHITPTQGFNI 192
>36867
          Length = 1083

 Score = 29.3 bits (64), Expect = 5.3,   Method: Compositional matrix adjust.
 Identities = 12/45 (26%), Positives = 21/45 (46%)
 Frame = +1

Query: 173 LYDPEAKQLRPACAQALTRIFRLSDQDRDHGLSDEELNAFQKSCF 217
           +YDP A++  P        + R +   + HG S    N+ ++ CF
Sbjct: 640 IYDPWAQRCEPGLRSLPVLLIRSASSRKWHGFSGRRFNSNEEMCF 774
>09123
          Length = 1944

 Score = 28.9 bits (63), Expect = 6.4,   Method: Compositional matrix adjust.
 Identities = 12/41 (29%), Positives = 20/41 (48%), Gaps = 11/41 (26%)
 Frame = +3

Query: 268  WTILRRFGYSDSLELTPDYLYPAL-----------HVPPGC 297
            W+++RR+G  D  E+   ++   L           H+PPGC
Sbjct: 1038 WSVIRRYGXLDGTEMVSTFVKSFLASSSLTEGITMHLPPGC 1160
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|27754130|ref|NP_079858.2| hypothetical protein
LOC66469 [Mus musculus]
         (201 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

02732                                                                  53   9e-08
13184                                                                  30   0.91 
04040                                                                  28   3.1  
>02732
          Length = 2083

 Score = 52.8 bits (125), Expect = 9e-08,   Method: Compositional matrix adjust.
 Identities = 28/74 (37%), Positives = 44/74 (59%), Gaps = 1/74 (1%)
 Frame = +1

Query: 28  LWQEKACVVAGLRRFGCMVCRWIAQDLSNLRSILDQHDVRLVGVGPEALGLQEFLDGGYF 87
           LW++   V+  +RR GC +CR  AQ+LS++R+ L   +V L  V  E LG +EF    Y 
Sbjct: 397 LWEKTGAVIMAVRRPGCSLCREEAQELSSIRAELQMRNVPLYAVIHETLGAEEFAP--YL 570

Query: 88  SGE-LYLDESKQIY 100
             + +YLD+ ++ Y
Sbjct: 571 KAKAIYLDKERKFY 612
>13184
          Length = 847

 Score = 29.6 bits (65), Expect = 0.91,   Method: Compositional matrix adjust.
 Identities = 18/45 (40%), Positives = 25/45 (55%)
 Frame = -2

Query: 27  SLWQEKACVVAGLRRFGCMVCRWIAQDLSNLRSILDQHDVRLVGV 71
           S++  KAC+  G    G  V + + QD    R + DQHDVR+V V
Sbjct: 222 SIFIVKACITGGD---GLEVIKEVDQDFIE-RELDDQHDVRVVNV 100
>04040
          Length = 1789

 Score = 27.7 bits (60), Expect = 3.1,   Method: Compositional matrix adjust.
 Identities = 10/27 (37%), Positives = 17/27 (62%)
 Frame = +1

Query: 161  HFIQKSPGDYVPQENILQALGISAEVC 187
            +F  ++PG  VPQ ++L    +SA +C
Sbjct: 1303 YFFHRTPGGGVPQRSVLAENRLSATLC 1383
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|13259378|ref|NP_077725.1| syntaxin 1B [Mus musculus]
         (288 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

08305                                                                  54   1e-07
08192                                                                  27   9.7  
>08305
          Length = 1314

 Score = 53.5 bits (127), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 56/244 (22%), Positives = 111/244 (45%), Gaps = 10/244 (4%)
 Frame = -3

Query: 29   MDEFFEQVEEIRGCIEKLSEDVEQVKKQHSAILAAPNPDEKTKQELEDLTADIKKTANKV 88
            + +   +  +I G +      V ++KK    ++ +P  D+      E +  ++ +   ++
Sbjct: 1120 LSDLLSKASQIDGDLSSYKSRVTELKKLQLDLVYSPFADKDAVSRYEGMIQELTRHXVRI 941

Query: 89   RSKLKAIEQSIEQEEGLNRSSAD---LRIRKTQHSTLSRKFVEVMTEYNATQSKYRDRCK 145
            R+ ++ +E   + ++ +++   D    R+ K Q + L+ +      E+   QS Y D+ K
Sbjct: 940  RNDIRQLEG--QADKYIDKKPDDEAFKRVSKQQLNGLTTQLAITTNEFFKCQSDYADKMK 767

Query: 146  DRIQRQLEITGRTTTNEELEDMLESGKLAIFTDDIKMDSQMTKQALNEIETRHNEIIKLE 205
            +R++ QL+  G + T+E    M  SG+         M S  T      +  +H    K  
Sbjct: 766  ERLKGQLQARGESVTDER*--MKFSGRTRT------MCSHRTSSLKCRMLQKH*GSWKSA 611

Query: 206  T-------SIRELHDMFVDMAMLVESQGEMIDRIEYNVEHSVDYVERAVSDTKKAVKYQS 258
            T       S+ +++ +F ++ ++V  QGE +D IE N+E    +VE       +AVK Q 
Sbjct: 610  TMTFLLLKSVTDVNMLFKELNLMVSQQGEKLDSIEQNIEQVEVHVESGKEQLTEAVKSQX 431

Query: 259  KARR 262
            KA R
Sbjct: 430  KAXR 419
>08192
          Length = 768

 Score = 26.9 bits (58), Expect = 9.7,   Method: Compositional matrix adjust.
 Identities = 13/32 (40%), Positives = 18/32 (56%)
 Frame = +2

Query: 201 IIKLETSIRELHDMFVDMAMLVESQGEMIDRI 232
           I ++   I  L +M VDM   +ESQ   IDR+
Sbjct: 323 IGEVSGMIGNLRNMAVDMGNEIESQNRQIDRV 418
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|21704016|ref|NP_663491.1| pleckstrin homology domain
containing, family B (evectins) member 2 [Mus musculus]
         (221 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

14481                                                                  52   1e-07
18755                                                                  47   6e-06
13952                                                                  37   0.006
20236                                                                  28   3.7  
>14481
          Length = 561

 Score = 52.4 bits (124), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 25/61 (40%), Positives = 39/61 (63%), Gaps = 3/61 (4%)
 Frame = -1

Query: 53  CINIRTGHECRDIQPPDGKPR---DCLLQIVCRDGKTISLCAESTDDCLAWKFTLQDSRT 109
           C+ I+TG E +    P  + R    CLL++  RDG  + LCAES DD  AW+++L+++RT
Sbjct: 537 CVRIKTGTEIKATTSPPDEVRGGVSCLLELDMRDGNHLLLCAESPDDMKAWQYSLEEART 358

Query: 110 N 110
           +
Sbjct: 357 S 355
>18755
          Length = 610

 Score = 47.0 bits (110), Expect = 6e-06,   Method: Compositional matrix adjust.
 Identities = 28/97 (28%), Positives = 51/97 (52%), Gaps = 2/97 (2%)
 Frame = +1

Query: 17  KRWKKNWFDLWSDGHLIYYDDQT-RQSIEDKVHMPVDCINIRTGHECRDIQ-PPDGKPRD 74
           KRW++ W  + SDG L   + +T ++    K  +  DC+ IRT  +C+ ++ P +   RD
Sbjct: 1   KRWRQKWVTISSDGILTVANYRTSKRRGRLKYDVRQDCMFIRTASQCQHLESPSEVHNRD 180

Query: 75  CLLQIVCRDGKTISLCAESTDDCLAWKFTLQDSRTNT 111
            L++++    + I+ C  S  D   W   +Q +R +T
Sbjct: 181 NLMELLLTGERRIAFCGLSPSDAELWYSCIQTARADT 291
>13952
          Length = 577

 Score = 37.0 bits (84), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 21/54 (38%), Positives = 30/54 (55%)
 Frame = -3

Query: 4   VKSGWLLRQSTILKRWKKNWFDLWSDGHLIYYDDQTRQSIEDKVHMPVDCINIR 57
           VK GWL++Q    K WK+ WF L +D  L Y+  Q     E K  +P++ I +R
Sbjct: 419 VKEGWLMKQGGRYKNWKRRWFIL-NDNCLYYF--QYTADKEPKGIIPLENIQVR 267
>20236
          Length = 681

 Score = 27.7 bits (60), Expect = 3.7,   Method: Compositional matrix adjust.
 Identities = 13/35 (37%), Positives = 23/35 (65%), Gaps = 3/35 (8%)
 Frame = -3

Query: 77  LQIVCRDGKTISLCAESTD---DCLAWKFTLQDSR 108
           +  VC+DG+T+ LC ++ D   +C A +  L++SR
Sbjct: 295 ITAVCKDGQTMVLCLKNVDKREECQAERSRLEESR 191
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|22122571|ref|NP_666191.1| guanylate cyclase activator
1B [Mus musculus]
         (201 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

14594                                                                  52   1e-07
00167                                                                  39   0.001
08108                                                                  37   0.005
33397                                                                  35   0.016
05237                                                                  35   0.023
14945                                                                  35   0.024
22063                                                                  34   0.048
01019                                                                  33   0.080
17484                                                                  32   0.22 
27864                                                                  31   0.26 
03732                                                                  31   0.28 
17977                                                                  31   0.34 
38338                                                                  31   0.39 
07678                                                                  30   0.50 
26849                                                                  30   0.73 
26019                                                                  29   1.6  
12455                                                                  28   2.2  
21693                                                                  28   2.7  
02570                                                                  27   3.8  
18571                                                                  27   4.1  
05918                                                                  27   4.9  
22490                                                                  27   5.8  
02383                                                                  27   6.2  
21153                                                                  27   7.6  
02147                                                                  26   8.8  
>14594
          Length = 1014

 Score = 52.0 bits (123), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 41/152 (26%), Positives = 70/152 (46%), Gaps = 1/152 (0%)
 Frame = +3

Query: 18  VAELQEWYKKFVVECPSGTLFMHEFKRFFKVTGNEEASQYVESMFRAFDKNGDNTIDFLE 77
           VAE +E +  F  +   GT+   E     +  G       ++ M    D +G+ TIDF E
Sbjct: 438 VAEFKEAFSLFDKD-GDGTITTSELGTVMRSLGQNPTENELQDMINEVDADGNGTIDFEE 614

Query: 78  YVAALNLVLRGS-LEHKLKWTFKIYDKDRNGCIDRLELLDIVEAIYKLKKACRAELDLEH 136
           ++  +   ++ +  E +L+  F+++DKD NG I   EL  ++  +               
Sbjct: 615 FLHMMARKMKDTDCEEELREAFRVFDKDGNGYISAAELRHVMTNL--------------- 749

Query: 137 QGQLLTPEEVVDRIFLLVDENGDGQLSLTEFI 168
            G+ LT EE VD +    D +GDG ++  EF+
Sbjct: 750 -GEKLTDEE-VDEMIKEADLDGDGMVNYEEFV 839
>00167
          Length = 2176

 Score = 39.3 bits (90), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 32/118 (27%), Positives = 56/118 (47%), Gaps = 2/118 (1%)
 Frame = +3

Query: 54  ASQYVESMFRAFDKNGDNTIDFLEYVAALNLVLRGSLEHKLKWTFKIYDKDRNGCIDRLE 113
            S+ +  +FR FDK+G  T+DF E++ AL   +       +K  F   DK  +G I   +
Sbjct: 834 TSEELNEVFRRFDKDGTGTLDFEEFLLALRPKMNEFRRKLVKKAFAKMDKTGDGIITADD 1013

Query: 114 LLDIVEAIYKLKKACRAELDLEHQGQLLTPEEVVDRIF--LLVDENGDGQLSLTEFIE 169
           L+      Y ++   R      +Q   LT ++V        +V +N DG +++ E+I+
Sbjct: 1014LV----GTYDVRSHPR------YQNGELTKKQVYQEFLDNFVVGDNDDGVITMAEWID 1157

 Score = 27.7 bits (60), Expect = 3.0,   Method: Compositional matrix adjust.
 Identities = 15/42 (35%), Positives = 26/42 (61%)
 Frame = +3

Query: 145 EVVDRIFLLVDENGDGQLSLTEFIEGARRDKWVMKMLQMDIN 186
           + + R F ++D+N D +LS+ EFI G R  + + KM   ++N
Sbjct: 729 KTIGRKFRIMDDNRDRKLSVDEFIVGCRECR-IAKMTSEELN 851
>08108
          Length = 818

 Score = 37.0 bits (84), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 28/111 (25%), Positives = 45/111 (40%)
 Frame = +2

Query: 59  ESMFRAFDKNGDNTIDFLEYVAALNLVLRGSLEHKLKWTFKIYDKDRNGCIDRLELLDIV 118
           ++ F  FD +G  +I   E   AL        + +     K YD D NG ID  E   +V
Sbjct: 134 QTAFAVFDTDGSGSISAGELGEALRAQGADITDDQTAELIKKYDSDSNGDIDTDEFRKLV 313

Query: 119 EAIYKLKKACRAELDLEHQGQLLTPEEVVDRIFLLVDENGDGQLSLTEFIE 169
           E    + +  ++ L                 +F  +D +GDGQ++ +E  E
Sbjct: 314 EGESDVARLAQSAL-----------------MFKSLDADGDGQITASEITE 415
>33397
          Length = 1723

 Score = 35.4 bits (80), Expect = 0.016,   Method: Compositional matrix adjust.
 Identities = 19/45 (42%), Positives = 27/45 (60%)
 Frame = +2

Query: 144 EEVVDRIFLLVDENGDGQLSLTEFIEGARRDKWVMKMLQMDINPG 188
           E V+D +F L DEN DG+LS  EF+   +R   VM+ L+   + G
Sbjct: 761 EHVIDVVFTLFDENNDGELSNKEFVSVMKR--RVMRGLEKPKDTG 889
>05237
          Length = 472

 Score = 35.0 bits (79), Expect = 0.023,   Method: Compositional matrix adjust.
 Identities = 24/78 (30%), Positives = 39/78 (50%)
 Frame = +3

Query: 91  EHKLKWTFKIYDKDRNGCIDRLELLDIVEAIYKLKKACRAELDLEHQGQLLTPEEVVDRI 150
           + +L+  F+++DKD NG I   EL  ++  +                G+ LT EEV D +
Sbjct: 24  DDELREAFRVFDKDGNGFISASELRHVMTNL----------------GEKLTDEEV-DEM 152

Query: 151 FLLVDENGDGQLSLTEFI 168
               D +GDGQ++  EF+
Sbjct: 153 IREADIDGDGQVNYEEFV 206
>14945
          Length = 1337

 Score = 34.7 bits (78), Expect = 0.024,   Method: Compositional matrix adjust.
 Identities = 25/90 (27%), Positives = 44/90 (48%), Gaps = 2/90 (2%)
 Frame = +1

Query: 20  ELQEWYKKFVVECPSGTLFMHEFKRFFKVTGNEEASQYVESMFRAFDKNGDNTIDFLEYV 79
           E++E +  F  +  SGT+   E K   +  G E   + ++ M    DK G  TIDF +++
Sbjct: 115 EIREAFDLFDADG-SGTIDAKELKVAMRALGFEPKKEEIKKMIAEIDKEGTGTIDFNDFL 291

Query: 80  AALN--LVLRGSLEHKLKWTFKIYDKDRNG 107
             +   +  + + E  LK  F+++D D  G
Sbjct: 292 TIMTQKMSEKDAKEEILK-AFRLFDDDETG 378

 Score = 30.0 bits (66), Expect = 0.73,   Method: Compositional matrix adjust.
 Identities = 20/68 (29%), Positives = 30/68 (44%)
 Frame = +1

Query: 51  NEEASQYVESMFRAFDKNGDNTIDFLEYVAALNLVLRGSLEHKLKWTFKIYDKDRNGCID 110
            EE  Q +   F  FD +G  TID  E   A+  +     + ++K      DK+  G ID
Sbjct: 97  TEEQKQEIREAFDLFDADGSGTIDAKELKVAMRALGFEPKKEEIKKMIAEIDKEGTGTID 276

Query: 111 RLELLDIV 118
             + L I+
Sbjct: 277 FNDFLTIM 300
>22063
          Length = 688

 Score = 33.9 bits (76), Expect = 0.048,   Method: Compositional matrix adjust.
 Identities = 25/90 (27%), Positives = 44/90 (48%), Gaps = 2/90 (2%)
 Frame = +3

Query: 20  ELQEWYKKFVVECPSGTLFMHEFKRFFKVTGNEEASQYVESMFRAFDKNGDNTIDFLEYV 79
           E++E +  F  +  SGT+   E K   +  G E   + ++ M    DK G  TIDF +++
Sbjct: 174 EIREAFDLFDADG-SGTIDAKELKVAMRALGFEPKKEEIKKMIAEIDKEGTGTIDFNDFL 350

Query: 80  AALN--LVLRGSLEHKLKWTFKIYDKDRNG 107
             +   +  + + E  LK  F+++D D  G
Sbjct: 351 TIMTQKMSEKDAKEEILK-AFRLFDDDETG 437

 Score = 29.3 bits (64), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 20/68 (29%), Positives = 30/68 (44%)
 Frame = +3

Query: 51  NEEASQYVESMFRAFDKNGDNTIDFLEYVAALNLVLRGSLEHKLKWTFKIYDKDRNGCID 110
            EE  Q +   F  FD +G  TID  E   A+  +     + ++K      DK+  G ID
Sbjct: 156 TEEQKQEIREAFDLFDADGSGTIDAKELKVAMRALGFEPKKEEIKKMIAEIDKEGTGTID 335

Query: 111 RLELLDIV 118
             + L I+
Sbjct: 336 FNDFLTIM 359
>01019
          Length = 1705

 Score = 33.1 bits (74), Expect = 0.080,   Method: Compositional matrix adjust.
 Identities = 23/74 (31%), Positives = 35/74 (47%)
 Frame = +1

Query: 95  KWTFKIYDKDRNGCIDRLELLDIVEAIYKLKKACRAELDLEHQGQLLTPEEVVDRIFLLV 154
           +W   ++DKD NG I   EL  +                + + G+ LT EEV D +    
Sbjct: 28  EWPLLVFDKDGNGFISAAELRHV----------------MTNLGEKLTDEEV-DEMIREA 156

Query: 155 DENGDGQLSLTEFI 168
           D +GDGQ++  EF+
Sbjct: 157 DIDGDGQVNYEEFV 198
>17484
          Length = 471

 Score = 31.6 bits (70), Expect = 0.22,   Method: Compositional matrix adjust.
 Identities = 17/64 (26%), Positives = 32/64 (50%)
 Frame = -3

Query: 47  KVTGNEEASQYVESMFRAFDKNGDNTIDFLEYVAALNLVLRGSLEHKLKWTFKIYDKDRN 106
           ++ G  E  + +   FRAFD+NGD  I   E   A+  + +   +  ++   +  DKD +
Sbjct: 298 RMKGGSEKDKEMRDAFRAFDQNGDGVISISELRQAMAKMGQKLSDADVESIIRDVDKDGD 119

Query: 107 GCID 110
           G ++
Sbjct: 118 GFVN 107

 Score = 27.7 bits (60), Expect = 3.6,   Method: Compositional matrix adjust.
 Identities = 14/60 (23%), Positives = 32/60 (53%)
 Frame = -3

Query: 20  ELQEWYKKFVVECPSGTLFMHEFKRFFKVTGNEEASQYVESMFRAFDKNGDNTIDFLEYV 79
           E+++ ++ F  +   G + + E ++     G + +   VES+ R  DK+GD  +++ E+ 
Sbjct: 268 EMRDAFRAFD-QNGDGVISISELRQAMAKMGQKLSDADVESIIRDVDKDGDGFVNYEEFT 92
>27864
          Length = 343

 Score = 31.2 bits (69), Expect = 0.26,   Method: Compositional matrix adjust.
 Identities = 20/57 (35%), Positives = 28/57 (49%)
 Frame = +1

Query: 58  VESMFRAFDKNGDNTIDFLEYVAALNLVLRGSLEHKLKWTFKIYDKDRNGCIDRLEL 114
           V  M   FD++   TI+F E+ A    V         +  F+ YD+D +G IDR EL
Sbjct: 130 VRLMIGMFDRDNSGTINFQEFQALWKYVT------DWQNCFRSYDRDNSGSIDRNEL 282
>03732
          Length = 1114

 Score = 31.2 bits (69), Expect = 0.28,   Method: Compositional matrix adjust.
 Identities = 22/69 (31%), Positives = 33/69 (47%), Gaps = 1/69 (1%)
 Frame = -1

Query: 58  VESMFRAFDKNGDNTIDFLEYVAALNLVLRGSLEHKLKWTFKIYDKDRNGCIDRLELLDI 117
           V  M   FD++   TI+F E+ A    V         +  F+ YD+D +G IDR EL + 
Sbjct: 985 VRLMIGMFDRDNSGTINFQEFQALWKYVT------DWQNCFRSYDRDNSGSIDRNELKNA 824

Query: 118 VEAI-YKLK 125
           +    Y+L 
Sbjct: 823 LTGFGYRLS 797
>17977
          Length = 445

 Score = 31.2 bits (69), Expect = 0.34,   Method: Compositional matrix adjust.
 Identities = 24/73 (32%), Positives = 34/73 (46%), Gaps = 2/73 (2%)
 Frame = +3

Query: 97  TFKIYDKDRNGCIDRLELLDIVEAIYKLKKACRAELDLEHQGQLLTPEEV--VDRIFLLV 154
            F+ YDKD  G ID          I  L++ACR         +   P +V  ++++F   
Sbjct: 234 AFRFYDKDGKGKID----------IDDLREACR---------KFDVPIDVWLLEQVFDYC 356

Query: 155 DENGDGQLSLTEF 167
           DEN DGQ+   EF
Sbjct: 357 DENRDGQIDYLEF 395
>38338
          Length = 463

 Score = 30.8 bits (68), Expect = 0.39,   Method: Compositional matrix adjust.
 Identities = 19/59 (32%), Positives = 30/59 (50%)
 Frame = -2

Query: 52  EEASQYVESMFRAFDKNGDNTIDFLEYVAALNLVLRGSLEHKLKWTFKIYDKDRNGCID 110
           E+ +++ E+ F  FDK+GD TI   E    +  + +   E +L+      D D NG ID
Sbjct: 177 EQIAEFKEA-FSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTID 4

 Score = 26.9 bits (58), Expect = 6.0,   Method: Compositional matrix adjust.
 Identities = 19/75 (25%), Positives = 31/75 (41%)
 Frame = -2

Query: 1   MGQQLSWEEAEAAGEMDVAELQEWYKKFVVECPSGTLFMHEFKRFFKVTGNEEASQYVES 60
           M  QL+ E+        +AE +E +  F  +   GT+   E     +  G       ++ 
Sbjct: 198 MADQLTEEQ--------IAEFKEAFSLFDKDG-DGTITTKELGTVMRSLGQNPTEAELQD 46

Query: 61  MFRAFDKNGDNTIDF 75
           M    D +G+ TIDF
Sbjct: 45  MINEVDADGNGTIDF 1
>07678
          Length = 958

 Score = 30.4 bits (67), Expect = 0.50,   Method: Compositional matrix adjust.
 Identities = 31/113 (27%), Positives = 50/113 (44%), Gaps = 3/113 (2%)
 Frame = +1

Query: 58  VESMFRAFDKNGDNTIDFLEYVAALNLVLRGSLEHKLKWTFKIYDKDRNGCIDRLELLDI 117
           ++ MF  FDK+   TIDF E++  L   +    +  ++  F+  DK  +G +  +E L  
Sbjct: 436 IQEMFTCFDKDZSGTIDFDEFLVKLRPPMSQMRKDLIQRAFQKLDKTGDGVV-TVEDLKG 612

Query: 118 VEAIYKLKKACRAELDLEHQGQLLTPEEVVDRIFL---LVDENGDGQLSLTEF 167
           V  + K  K    E            EE + RIFL       + DG+++  EF
Sbjct: 613 VYNVTKHPKYLNGEW----------TEERILRIFLDSFDSPNDKDGKITKEEF 741
>26849
          Length = 649

 Score = 30.0 bits (66), Expect = 0.73,   Method: Compositional matrix adjust.
 Identities = 16/39 (41%), Positives = 24/39 (61%), Gaps = 1/39 (2%)
 Frame = +3

Query: 146 VVDRIFLLVDENGDGQLSLTEFIEG-ARRDKWVMKMLQM 183
           V+ R F  +D NGDGQ+++T+F    + RD  + K  QM
Sbjct: 387 VIHRAFDKLDANGDGQITITDFKRCYSVRDHPLYKSGQM 503
>26019
          Length = 1561

 Score = 28.9 bits (63), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 19/61 (31%), Positives = 31/61 (50%), Gaps = 10/61 (16%)
 Frame = +2

Query: 123 KLKKACRAELDLEHQGQL----------LTPEEVVDRIFLLVDENGDGQLSLTEFIEGAR 172
           +L K  R +LDL++ G L          L    +V R+  + D +G+G++   EFIEG  
Sbjct: 101 RLGKRFR-KLDLDNSGSLSIDEFMSLPELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGIS 277

Query: 173 R 173
           +
Sbjct: 278 Q 280
>12455
          Length = 853

 Score = 28.1 bits (61), Expect = 2.2,   Method: Compositional matrix adjust.
 Identities = 16/57 (28%), Positives = 25/57 (43%)
 Frame = -2

Query: 6   SWEEAEAAGEMDVAELQEWYKKFVVECPSGTLFMHEFKRFFKVTGNEEASQYVESMF 62
           +WE     GE        +   F++   SG  F  +FK    V GNE  + Y++ +F
Sbjct: 705 NWETKTLMGETKEELRNRYCSAFLIPSVSGGYFYADFKIRNLVKGNE*KASYIDHLF 535
>21693
          Length = 407

 Score = 28.1 bits (61), Expect = 2.7,   Method: Compositional matrix adjust.
 Identities = 11/16 (68%), Positives = 14/16 (87%)
 Frame = +2

Query: 151 FLLVDENGDGQLSLTE 166
           FLL++ENGDG L LT+
Sbjct: 206 FLLINENGDGSLHLTK 253
>02570
          Length = 1067

 Score = 27.3 bits (59), Expect = 3.8,   Method: Compositional matrix adjust.
 Identities = 11/41 (26%), Positives = 20/41 (48%)
 Frame = -3

Query: 24  WYKKFVVECPSGTLFMHEFKRFFKVTGNEEASQYVESMFRA 64
           W+   VV CP    F++   R ++   ++  S+ +  MFR 
Sbjct: 540 WFLLVVVLCPIPLWFIYHAVRTYRQNSDQPISEIIAIMFRP 418
>18571
          Length = 821

 Score = 27.3 bits (59), Expect = 4.1,   Method: Compositional matrix adjust.
 Identities = 13/21 (61%), Positives = 16/21 (76%)
 Frame = -2

Query: 151 FLLVDENGDGQLSLTEFIEGA 171
           F  +D+N DG+LSL EFIEG 
Sbjct: 811 FRQMDKNLDGKLSLEEFIEGP 749
>05918
          Length = 1245

 Score = 26.9 bits (58), Expect = 4.9,   Method: Compositional matrix adjust.
 Identities = 21/74 (28%), Positives = 36/74 (48%), Gaps = 4/74 (5%)
 Frame = +1

Query: 98  FKIYDKDRNGCIDRLELLDIVEAIY-KLKKACRAELDLEHQGQLLTPEEV---VDRIFLL 153
           FK++D D N  +D +E+   +   + +   A + E   +   ++ T EE+   VD +   
Sbjct: 112 FKMHDYDNNNKLDGVEIGKALTHFHDEHDNAAQDEGQEKPPVKVFTDEEISNIVDTVIND 291

Query: 154 VDENGDGQLSLTEF 167
            DEN DG +   EF
Sbjct: 292 NDENNDGYVEYFEF 333
>22490
          Length = 743

 Score = 26.9 bits (58), Expect = 5.8,   Method: Compositional matrix adjust.
 Identities = 12/30 (40%), Positives = 19/30 (63%)
 Frame = -1

Query: 144 EEVVDRIFLLVDENGDGQLSLTEFIEGARR 173
           E++VD I    D + DG +  TEF++G +R
Sbjct: 476 EDIVDEILREDDLDKDGYVDYTEFMKGQKR 387
>02383
          Length = 2075

 Score = 26.9 bits (58), Expect = 6.2,   Method: Compositional matrix adjust.
 Identities = 15/47 (31%), Positives = 22/47 (46%)
 Frame = -1

Query: 61   MFRAFDKNGDNTIDFLEYVAALNLVLRGSLEHKLKWTFKIYDKDRNG 107
            MF   + NGD      +Y   L    +G+L   +KW F  +  D+NG
Sbjct: 1748 MFSKINVNGDGAHPLFKY---LKKKQKGTLGDFIKWNFSKFLVDKNG 1617
>21153
          Length = 564

 Score = 26.6 bits (57), Expect = 7.6,   Method: Compositional matrix adjust.
 Identities = 22/60 (36%), Positives = 26/60 (43%), Gaps = 8/60 (13%)
 Frame = -1

Query: 57  YVESMFRAFDKNGDNTIDFLEYVAALNLVLRGSLEH--------KLKWTFKIYDKDRNGC 108
           YVES+ +AFD  G   +D      AL L L  S  H        K+KW     DK   GC
Sbjct: 363 YVESLVQAFDTIGFRDLD-QAITKALELSLICSFAHISC*TGTGKVKWV----DKAEGGC 199
>02147
          Length = 1547

 Score = 26.2 bits (56), Expect = 8.8,   Method: Compositional matrix adjust.
 Identities = 13/32 (40%), Positives = 18/32 (56%)
 Frame = +2

Query: 26  KKFVVECPSGTLFMHEFKRFFKVTGNEEASQY 57
           KKF  E P  +  +H+ +RFF V G E+   Y
Sbjct: 653 KKFEAEAPISSASLHQSERFF-VAGGEDFKMY 745
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|12963591|ref|NP_075720.1| stomatin-like protein 2
[Mus musculus]
         (353 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

05561                                                                  53   2e-07
07016                                                                  44   1e-04
02052                                                                  36   0.024
>05561
          Length = 1025

 Score = 52.8 bits (125), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 33/104 (31%), Positives = 63/104 (60%)
 Frame = +3

Query: 111 DPYKASYGVEDPEYAVTQLAQTTMRSELGKLSLDKVFRERESLNANIVDAINQAADCWGI 170
           D   +   VED   +   LA TT+R+ LG  +L ++  +RE+++  +  +++ A D WGI
Sbjct: 6   DATASVNNVEDAARSTQLLAATTLRNVLGTKNLAEILSDREAISHFMQSSLDDATDPWGI 185

Query: 171 RCLRYEIKDIHVPPRVKESMQMQVEAERRKRATVLESEGTRESA 214
           +  R E+KD+ +P +++ +M  + EA R  RA V+ +EG ++++
Sbjct: 186 KVERVEVKDVRLPVQLQRAMAAEAEAAREARAKVIAAEGEQKAS 317
>07016
          Length = 1481

 Score = 43.9 bits (102), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 27/86 (31%), Positives = 55/86 (63%)
 Frame = +3

Query: 129 LAQTTMRSELGKLSLDKVFRERESLNANIVDAINQAADCWGIRCLRYEIKDIHVPPRVKE 188
           LA TT+R+ LG  +L ++  +RE+++  +   ++ A   WG++  R E+KD+ +P +++ 
Sbjct: 60  LAATTLRNVLGTRNLAEILSDREAISHFMQTTLDDATHPWGVKVERVEVKDVRLPVQLQR 239

Query: 189 SMQMQVEAERRKRATVLESEGTRESA 214
           +M  + EA R  RA V+ +EG ++++
Sbjct: 240 AMAAEAEAAREARAKVIAAEGEQKAS 317
>02052
          Length = 1896

 Score = 35.8 bits (81), Expect = 0.024,   Method: Compositional matrix adjust.
 Identities = 31/115 (26%), Positives = 55/115 (47%)
 Frame = -2

Query: 120  EDPEYAVTQLAQTTMRSELGKLSLDKVFRERESLNANIVDAINQAADCWGIRCLRYEIKD 179
            E  E+ + Q  +  +R+ LG LS++ ++++R+     + +  +      GI  L + IKD
Sbjct: 1868 EHIEHVILQTLEGHLRAILGTLSVEAIYQDRDQFAQLVREVASPDVGKMGIEILSFTIKD 1689

Query: 180  IHVPPRVKESMQMQVEAERRKRATVLESEGTRESAINVAEGKKQAQILASEAEKA 234
            I+      + +Q      R + A V      R++ I VAE  + A I  +E EKA
Sbjct: 1688 IY------DDVQYLSSLGRAQTANV-----KRDADIGVAEANRDAGIREAECEKA 1557
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|148747363|ref|NP_663351.3| lysophosphatidylcholine
acyltransferase 1 [Mus musculus]
         (534 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

26019                                                                  54   2e-07
07678                                                                  40   0.002
33397                                                                  34   0.14 
18120                                                                  28   6.6  
>26019
          Length = 1561

 Score = 53.5 bits (127), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 32/118 (27%), Positives = 59/118 (50%), Gaps = 6/118 (5%)
 Frame = +2

Query: 367 IRLPEFAAYLEVPVSDALEDMFSLFDESGGGEIDLREYVVALSVVCRPSQTLATIQLAFK 426
           + + EF +  E+  +  ++ +  +FD  G GE+D +E++  +S         + ++ AFK
Sbjct: 149 LSIDEFMSLPELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGISQFSVKGDKESKLRFAFK 328

Query: 427 MYGSPEDGSIDEANLSCILKTALGVSELTVTDLFQAIDQEDKGR------ITFDDFCG 478
           +Y   +DG I    L  +LK  +G + L  T L Q +D+    R      I+F++FC 
Sbjct: 329 IYDMDKDGYISNGELFQVLKMMVG-NNLKDTQLQQIVDKPSSMRTPTVMEISFEEFCA 499
>07678
          Length = 958

 Score = 40.0 bits (92), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 42/139 (30%), Positives = 64/139 (46%), Gaps = 8/139 (5%)
 Frame = +1

Query: 314 CQLALAEG-----QLRLPADTCLLEFARLVRGLGLKPENLEKDLDKYSESARMKRGEKIR 368
           CQ ALA       +LRL    CL   A  ++GL  K + ++ D ++  +    K+G    
Sbjct: 238 CQKALAVATDPVEKLRLA---CLARGAAGIKGLARKFKIMDDDGNRSLDFKEFKKG---- 396

Query: 369 LPEFAAYLEVPVSDALEDMFSLFDESGGGEIDLREYVVALSVVCRP--SQTLAT-IQLAF 425
           + EF   L     D +++MF+ FD+   G ID  E++V L    RP  SQ     IQ AF
Sbjct: 397 ITEFG--LTQFEGDVIQEMFTCFDKDZSGTIDFDEFLVKL----RPPMSQMRKDLIQRAF 558

Query: 426 KMYGSPEDGSIDEANLSCI 444
           +      DG +   +L  +
Sbjct: 559 QKLDKTGDGVVTVEDLKGV 615
>33397
          Length = 1723

 Score = 34.3 bits (77), Expect = 0.14,   Method: Compositional matrix adjust.
 Identities = 28/100 (28%), Positives = 43/100 (43%), Gaps = 5/100 (5%)
 Frame = +3

Query: 384 LEDMFSLFDESGGGEIDLREYVVALSVVCRPSQTLATIQLAFKMYGSPEDGSIDEANLSC 443
            E  F +FD +G GE+DL E+     V+   +   A      +       GS+D    S 
Sbjct: 198 FEIAFRMFDINGDGELDLEEFNRVQGVIRNQTHVGA------RHRDHAVTGSVDHGLSSS 359

Query: 444 ILKTALGVS---ELTVTDL--FQAIDQEDKGRITFDDFCG 478
           +L    G +   +LT  +   FQ   Q +  RI F+ +CG
Sbjct: 360 LLSYFFGKNGKKKLTHKEFLDFQRQLQREINRIEFERYCG 479
>18120
          Length = 777

 Score = 28.5 bits (62), Expect = 6.6,   Method: Compositional matrix adjust.
 Identities = 14/51 (27%), Positives = 23/51 (45%)
 Frame = -2

Query: 228 GVPVQPVVLRYPNKLDTITWTWQGPGALKILWLTLCQFQNQVEIEFLPVYC 278
           G P +   L+ P   D    TW G  + +  +  LC+F N   + +  +YC
Sbjct: 398 GRPYRLRWLKVPQCCDF*AVTWVGWNSAQQSYFVLCEFVNMSTLHYWMIYC 246
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|171543853|ref|NP_032660.2| microtubule-associated
protein 1B [Mus musculus]
         (2464 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

20910                                                                  56   2e-07
15667                                                                  33   1.8  
19909                                                                  31   5.3  
>20910
          Length = 490

 Score = 56.2 bits (134), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 35/88 (39%), Positives = 53/88 (60%), Gaps = 4/88 (4%)
 Frame = +3

Query: 2372 FFKRVRSSYYVVSGNDPAAEEPSRAVLDALLEGKAQW-GSNMQ-VTLIPTHDSEVMREWY 2429
            FFKRVR+  YV+S ++P  +     VL+ L+E KA W  SN Q VT+IPT+++ +++ W 
Sbjct: 33   FFKRVRAKNYVLSASNPNPK-----VLEMLIEAKATWDKSNEQEVTVIPTYETPILQHWL 197

Query: 2430 QETHEKQQDLNIMV--LASSSTVVMQDE 2455
                EK  +  I++   AS  TV +QD 
Sbjct: 198  AVHKEKLAESKIVITPAASRCTVRLQDH 281
>15667
          Length = 1987

 Score = 32.7 bits (73), Expect = 1.8,   Method: Composition-based stats.
 Identities = 30/105 (28%), Positives = 46/105 (43%), Gaps = 7/105 (6%)
 Frame = -1

Query: 1610 PRPMSISPPDFSPKTAKSRTPVQDHRSEQSSMSIEFG----QESPEHSLAMDFSRQSPDH 1665
            PRP+SI PP   P   +S++P+   +S   S S+  G      SP    +   SR SP+ 
Sbjct: 1618 PRPLSIGPP-ILP*GPRSKSPLPRPKSRLESKSLLPGYWSRNSSPSLLSSKRLSRVSPEK 1442

Query: 1666 PTLGASVLHITENGPTEVDYSPS---DIQDSSLSHKIPPTEEPSY 1707
            P L + V     N   +  +      D++ S L H+ P    P +
Sbjct: 1441 PGLSSLVFPCGRNXDQDHLFLCQIHLDLEISXLYHRTPHIFCPDF 1307
>19909
          Length = 898

 Score = 31.2 bits (69), Expect = 5.3,   Method: Compositional matrix adjust.
 Identities = 12/49 (24%), Positives = 26/49 (53%)
 Frame = -3

Query: 427 PVKSSKEMQYFMQQWTGTNKDKAELILPNGQEVDIPISYLTSVSSLIVW 475
           P+  SK +++F + +    KDK  +  P    +  P+SY +  ++++ W
Sbjct: 569 PIYVSKRVEHFTKLFLDCVKDKGTVSFPRDHTLANPLSYFSDKNNILPW 423
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|172072627|ref|NP_080280.3| 5'-nucleotidase, cytosolic
III [Mus musculus]
         (331 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

16803                                                                  53   2e-07
05383                                                                  31   0.56 
27053                                                                  29   3.2  
08201                                                                  28   5.6  
17050                                                                  27   9.9  
>16803
          Length = 417

 Score = 52.8 bits (125), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 24/46 (52%), Positives = 40/46 (86%)
 Frame = +1

Query: 286 VEHILKIGYLNDRVDELLEKYMDSYDIVLVKEESLEVVNSILQKTL 331
           +E +LKIG+LN +V+E L++Y DSYDIV+V+++++ VVNS+++K L
Sbjct: 4   LECMLKIGFLNFKVEENLQQYKDSYDIVIVQDQTMSVVNSLMRKIL 141
>05383
          Length = 1210

 Score = 31.2 bits (69), Expect = 0.56,   Method: Compositional matrix adjust.
 Identities = 15/38 (39%), Positives = 19/38 (50%)
 Frame = -3

Query: 83  DFDMTLSRFSYNGKRCPTCHNIIDNCKLVTDECRRKLL 120
           D     SR S  GK CP CH++I N  +V    R K +
Sbjct: 893 DVASAWSRVSVFGKVCPKCHDVIRNTFVVVSPARGKTI 780
>27053
          Length = 822

 Score = 28.9 bits (63), Expect = 3.2,   Method: Compositional matrix adjust.
 Identities = 14/40 (35%), Positives = 22/40 (55%)
 Frame = -2

Query: 209 IRQAGVYHSNVKVVSNFMDFDENGVLKGFKGELIHVFNKH 248
           I++AG +  N +     + F E G L+  KGE +H  N+H
Sbjct: 254 IQEAGCHGEN-QNTKQSLQFPETG*LEEEKGECVHTCNQH 138
>08201
          Length = 910

 Score = 28.1 bits (61), Expect = 5.6,   Method: Compositional matrix adjust.
 Identities = 17/40 (42%), Positives = 22/40 (55%)
 Frame = -3

Query: 86  MTLSRFSYNGKRCPTCHNIIDNCKLVTDECRRKLLQLKEQ 125
           +T ++ S N      CHN+IDN KL   EC  +L  L EQ
Sbjct: 578 LTENKQSLNKAILQVCHNLIDNLKL---ECTPELKNLLEQ 468
>17050
          Length = 1852

 Score = 27.3 bits (59), Expect = 9.9,   Method: Compositional matrix adjust.
 Identities = 11/25 (44%), Positives = 16/25 (64%)
 Frame = -2

Query: 82   TDFDMTLSRFSYNGKRCPTCHNIID 106
            TDF++T  +F  N K CP+  N +D
Sbjct: 1692 TDFNLTCYKFYNNRKLCPSNQNKVD 1618
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|40254633|ref|NP_032215.2| guanylate cyclase activator
1a (retina) [Mus musculus]
         (202 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

26019                                                                  52   2e-07
14594                                                                  45   2e-05
07198                                                                  40   6e-04
01773                                                                  40   9e-04
05237                                                                  36   0.009
22063                                                                  35   0.016
14945                                                                  35   0.018
15966                                                                  34   0.050
01019                                                                  32   0.15 
33397                                                                  32   0.17 
32088                                                                  32   0.18 
07678                                                                  31   0.32 
00167                                                                  30   0.46 
20751                                                                  30   0.49 
18571                                                                  30   0.69 
08380                                                                  30   0.83 
38338                                                                  29   1.3  
04643                                                                  29   1.6  
17977                                                                  27   4.3  
17484                                                                  27   4.5  
24587                                                                  27   7.5  
>26019
          Length = 1561

 Score = 51.6 bits (122), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 29/90 (32%), Positives = 52/90 (57%), Gaps = 1/90 (1%)
 Frame = +2

Query: 31  SGQLTLYEFRQFFGLKNLSPSASQYVEQMFETFDFNKDGYIDFMEYVAALS-LVLKGKVE 89
           SG L++ EF     L+      +  V+++ + FD + +G +DF E++  +S   +KG  E
Sbjct: 140 SGSLSIDEFMSLPELQQ-----NPLVQRVIDIFDTDGNGEVDFKEFIEGISQFSVKGDKE 304

Query: 90  QKLRWYFKLYDVDGNGCIDRDELLTIIRAI 119
            KLR+ FK+YD+D +G I   EL  +++ +
Sbjct: 305 SKLRFAFKIYDMDKDGYISNGELFQVLKMM 394

 Score = 30.8 bits (68), Expect = 0.42,   Method: Compositional matrix adjust.
 Identities = 17/73 (23%), Positives = 33/73 (45%)
 Frame = +2

Query: 90  QKLRWYFKLYDVDGNGCIDRDELLTIIRAIRTINPWSDSSMSAEEFTDTVFAKIDINGDG 149
           Q+L   F+  D+D +G +  DE +++              +        V    D +G+G
Sbjct: 98  QRLGKRFRKLDLDNSGSLSIDEFMSL------------PELQQNPLVQRVIDIFDTDGNG 241

Query: 150 ELSLEEFMEGVQK 162
           E+  +EF+EG+ +
Sbjct: 242 EVDFKEFIEGISQ 280
>14594
          Length = 1014

 Score = 45.1 bits (105), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 32/110 (29%), Positives = 60/110 (54%), Gaps = 1/110 (0%)
 Frame = +3

Query: 49  SPSASQYVEQMFETFDFNKDGYIDFMEYVAALSLVLKGK-VEQKLRWYFKLYDVDGNGCI 107
           +P+ ++ ++ M    D + +G IDF E++  ++  +K    E++LR  F+++D DGNG I
Sbjct: 537 NPTENE-LQDMINEVDADGNGTIDFEEFLHMMARKMKDTDCEEELREAFRVFDKDGNGYI 713

Query: 108 DRDELLTIIRAIRTINPWSDSSMSAEEFTDTVFAKIDINGDGELSLEEFM 157
              EL       R +       ++ EE  D +  + D++GDG ++ EEF+
Sbjct: 714 SAAEL-------RHVMTNLGEKLTDEE-VDEMIKEADLDGDGMVNYEEFV 839

 Score = 34.7 bits (78), Expect = 0.024,   Method: Compositional matrix adjust.
 Identities = 21/67 (31%), Positives = 37/67 (55%)
 Frame = +3

Query: 91  KLRWYFKLYDVDGNGCIDRDELLTIIRAIRTINPWSDSSMSAEEFTDTVFAKIDINGDGE 150
           + +  F L+D DG+G I   EL T++R++   NP  +      E  D +  ++D +G+G 
Sbjct: 444 EFKEAFSLFDKDGDGTITTSELGTVMRSLGQ-NPTEN------ELQDMI-NEVDADGNGT 599

Query: 151 LSLEEFM 157
           +  EEF+
Sbjct: 600 IDFEEFL 620

 Score = 33.9 bits (76), Expect = 0.041,   Method: Compositional matrix adjust.
 Identities = 19/88 (21%), Positives = 42/88 (47%)
 Frame = +3

Query: 31  SGQLTLYEFRQFFGLKNLSPSASQYVEQMFETFDFNKDGYIDFMEYVAALSLVLKGKVEQ 90
           +G +   EF      K       + + + F  FD + +GYI   E    ++ + +   ++
Sbjct: 591 NGTIDFEEFLHMMARKMKDTDCEEELREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDE 770

Query: 91  KLRWYFKLYDVDGNGCIDRDELLTIIRA 118
           ++    K  D+DG+G ++ +E +T++ A
Sbjct: 771 EVDEMIKEADLDGDGMVNYEEFVTMMTA 854
>07198
          Length = 1675

 Score = 40.0 bits (92), Expect = 6e-04,   Method: Compositional matrix adjust.
 Identities = 38/126 (30%), Positives = 55/126 (43%)
 Frame = -3

Query: 32  GQLTLYEFRQFFGLKNLSPSASQYVEQMFETFDFNKDGYIDFMEYVAALSLVLKGKVEQK 91
           G L   E+  FF + N  P     +E+     D NKDG I   E++   +    G     
Sbjct: 437 GSLNSKEYFAFF-MPNSFPQLE--LERFMRQSDKNKDGTISMEEFMPEGAT---GDTRTS 276

Query: 92  LRWYFKLYDVDGNGCIDRDELLTIIRAIRTINPWSDSSMSAEEFTDTVFAKIDINGDGEL 151
               FK YD D +G       L++  A+  INP SD     E   + +F   D+N DG+L
Sbjct: 275 SEESFKNYDKDKDGS------LSLEEAMEWINPSSDEHADVE--VEHLFTIGDVNHDGKL 120

Query: 152 SLEEFM 157
           S +E +
Sbjct: 119 SKDEIL 102
>01773
          Length = 1950

 Score = 39.7 bits (91), Expect = 9e-04,   Method: Compositional matrix adjust.
 Identities = 40/142 (28%), Positives = 61/142 (42%), Gaps = 4/142 (2%)
 Frame = +1

Query: 22  YKKFMTECPS---GQLTLYEFRQFFGLKNLSPSASQYVEQMFETFDFNK-DGYIDFMEYV 77
           YK+   E      G L + E R+ F     S S SQ +   F  FD  + D  I F  + 
Sbjct: 160 YKQLFKEADKNNDGYLEIKELRELFKRNGSSLSDSQ-IADTFVFFDGPRGDKRITFEXFC 336

Query: 78  AALSLVLKGKVEQKLRWYFKLYDVDGNGCIDRDELLTIIRAIRTINPWSDSSMSAEEFTD 137
             L  ++     QKL   FK  D  G+G +DRDEL  ++         S    +A++ + 
Sbjct: 337 KGLDQIVM--FVQKLAELFKAKDKSGDGYLDRDELKALL-------DESGQKFTADDVS- 486

Query: 138 TVFAKIDINGDGELSLEEFMEG 159
            +    D N D ++  EEF++ 
Sbjct: 487 AILKSADKNNDNKICFEEFVDA 552
>05237
          Length = 472

 Score = 36.2 bits (82), Expect = 0.009,   Method: Compositional matrix adjust.
 Identities = 21/70 (30%), Positives = 37/70 (52%)
 Frame = +3

Query: 88  VEQKLRWYFKLYDVDGNGCIDRDELLTIIRAIRTINPWSDSSMSAEEFTDTVFAKIDING 147
            + +LR  F+++D DGNG I   EL  ++  +             +E  D +  + DI+G
Sbjct: 21  TDDELREAFRVFDKDGNGFISASELRHVMTNL--------GEKLTDEEVDEMIREADIDG 176

Query: 148 DGELSLEEFM 157
           DG+++ EEF+
Sbjct: 177 DGQVNYEEFV 206
>22063
          Length = 688

 Score = 35.4 bits (80), Expect = 0.016,   Method: Compositional matrix adjust.
 Identities = 22/69 (31%), Positives = 35/69 (50%)
 Frame = +3

Query: 89  EQKLRWYFKLYDVDGNGCIDRDELLTIIRAIRTINPWSDSSMSAEEFTDTVFAKIDINGD 148
           +Q++R  F L+D DG+G ID  EL   +RA+    P        +E    + A+ID  G 
Sbjct: 168 KQEIREAFDLFDADGSGTIDAKELKVAMRAL-GFEP-------KKEEIKKMIAEIDKEGT 323

Query: 149 GELSLEEFM 157
           G +   +F+
Sbjct: 324 GTIDFNDFL 350
>14945
          Length = 1337

 Score = 35.0 bits (79), Expect = 0.018,   Method: Compositional matrix adjust.
 Identities = 22/69 (31%), Positives = 35/69 (50%)
 Frame = +1

Query: 89  EQKLRWYFKLYDVDGNGCIDRDELLTIIRAIRTINPWSDSSMSAEEFTDTVFAKIDINGD 148
           +Q++R  F L+D DG+G ID  EL   +RA+    P        +E    + A+ID  G 
Sbjct: 109 KQEIREAFDLFDADGSGTIDAKELKVAMRAL-GFEP-------KKEEIKKMIAEIDKEGT 264

Query: 149 GELSLEEFM 157
           G +   +F+
Sbjct: 265 GTIDFNDFL 291
>15966
          Length = 362

 Score = 33.9 bits (76), Expect = 0.050,   Method: Compositional matrix adjust.
 Identities = 26/92 (28%), Positives = 42/92 (45%)
 Frame = +2

Query: 68  DGYIDFMEYVAALSLVLKGKVEQKLRWYFKLYDVDGNGCIDRDELLTIIRAIRTINPWSD 127
           D  I F E+   L  ++     QKL   FK  D  G+G +DRDEL  ++         S 
Sbjct: 74  DKRITFEEFCKGLDQIVM--FVQKLAELFKAKDKSGDGYLDRDELKALL-------DESG 226

Query: 128 SSMSAEEFTDTVFAKIDINGDGELSLEEFMEG 159
              +A++ +  +    D N D ++  EEF++ 
Sbjct: 227 QKFTADDVS-AILKSADKNNDNKICFEEFVDA 319
>01019
          Length = 1705

 Score = 32.3 bits (72), Expect = 0.15,   Method: Compositional matrix adjust.
 Identities = 19/64 (29%), Positives = 32/64 (50%)
 Frame = +1

Query: 94  WYFKLYDVDGNGCIDRDELLTIIRAIRTINPWSDSSMSAEEFTDTVFAKIDINGDGELSL 153
           W   ++D DGNG I   EL  ++  +             +E  D +  + DI+GDG+++ 
Sbjct: 31  WPLLVFDKDGNGFISAAELRHVMTNL--------GEKLTDEEVDEMIREADIDGDGQVNY 186

Query: 154 EEFM 157
           EEF+
Sbjct: 187 EEFV 198
>33397
          Length = 1723

 Score = 32.0 bits (71), Expect = 0.17,   Method: Compositional matrix adjust.
 Identities = 16/30 (53%), Positives = 21/30 (70%), Gaps = 2/30 (6%)
 Frame = +3

Query: 137 DTVFAKIDINGDGELSLEEF--MEGVQKDQ 164
           +  F   DINGDGEL LEEF  ++GV ++Q
Sbjct: 201 EIAFRMFDINGDGELDLEEFNRVQGVIRNQ 290
>32088
          Length = 1928

 Score = 32.0 bits (71), Expect = 0.18,   Method: Compositional matrix adjust.
 Identities = 22/66 (33%), Positives = 32/66 (48%)
 Frame = +1

Query: 91   KLRWYFKLYDVDGNGCIDRDELLTIIRAIRTINPWSDSSMSAEEFTDTVFAKIDINGDGE 150
            +LR  F   D D NG I   EL +  RA+    P  +          T+ +K D +GDG 
Sbjct: 946  ELRSVFDSIDDDNNGHISXGELDSAFRAVGLNIPGYE--------LRTIMSKYDASGDGR 1101

Query: 151  LSLEEF 156
            L+++EF
Sbjct: 1102 LNMDEF 1119

 Score = 28.1 bits (61), Expect = 2.4,   Method: Compositional matrix adjust.
 Identities = 16/60 (26%), Positives = 29/60 (48%)
 Frame = +1

Query: 56   VEQMFETFDFNKDGYIDFMEYVAALSLVLKGKVEQKLRWYFKLYDVDGNGCIDRDELLTI 115
            +  +F++ D + +G+I   E  +A   V       +LR     YD  G+G ++ DE  T+
Sbjct: 949  LRSVFDSIDDDNNGHISXGELDSAFRAVGLNIPGYELRTIMSKYDASGDGRLNMDEFRTL 1128
>07678
          Length = 958

 Score = 31.2 bits (69), Expect = 0.32,   Method: Compositional matrix adjust.
 Identities = 31/137 (22%), Positives = 63/137 (45%), Gaps = 4/137 (2%)
 Frame = +1

Query: 24  KFMTECPSGQLTLYEFRQFFGLKNLSPSASQYVEQMFETFDFNKDGYIDFMEYVAALSLV 83
           K M +  +  L   EF++      L+      +++MF  FD ++ G IDF E++  L   
Sbjct: 340 KIMDDDGNRSLDFKEFKKGITEFGLTQFEGDVIQEMFTCFDKDZSGTIDFDEFLVKLRPP 519

Query: 84  LKGKVEQKLRWYFKLYDVDGNGCIDRDEL---LTIIRAIRTIN-PWSDSSMSAEEFTDTV 139
           +    +  ++  F+  D  G+G +  ++L     + +  + +N  W++  +    F D+ 
Sbjct: 520 MSQMRKDLIQRAFQKLDKTGDGVVTVEDLKGVYNVTKHPKYLNGEWTEERI-LRIFLDSF 696

Query: 140 FAKIDINGDGELSLEEF 156
            +  D   DG+++ EEF
Sbjct: 697 DSPND--KDGKITKEEF 741
>00167
          Length = 2176

 Score = 30.4 bits (67), Expect = 0.46,   Method: Compositional matrix adjust.
 Identities = 25/115 (21%), Positives = 56/115 (48%), Gaps = 4/115 (3%)
 Frame = +3

Query: 48  LSPSASQYVEQMFETFDFNKDGYIDFMEYVAALSLVLKGKVEQKLRWYFKLYDVDGNGCI 107
           ++   S+ + ++F  FD +  G +DF E++ AL   +     + ++  F   D  G+G I
Sbjct: 822 IAKMTSEELNEVFRRFDKDGTGTLDFEEFLLALRPKMNEFRRKLVKKAFAKMDKTGDGII 1001

Query: 108 DRDELLTIIRAIRTINPWSDSSMSA----EEFTDTVFAKIDINGDGELSLEEFME 158
             D+L+     +R+   + +  ++     +EF D     +  N DG +++ E+++
Sbjct: 1002TADDLVGTY-DVRSHPRYQNGELTKKQVYQEFLDNFV--VGDNDDGVITMAEWID 1157
>20751
          Length = 861

 Score = 30.4 bits (67), Expect = 0.49,   Method: Compositional matrix adjust.
 Identities = 16/36 (44%), Positives = 21/36 (58%)
 Frame = -2

Query: 70  YIDFMEYVAALSLVLKGKVEQKLRWYFKLYDVDGNG 105
           Y DF  Y   L ++ +   +Q L   FK+YDVDGNG
Sbjct: 764 YRDFPMYNPYLDMIGRRPAKQSLTG-FKVYDVDGNG 660
>18571
          Length = 821

 Score = 30.0 bits (66), Expect = 0.69,   Method: Compositional matrix adjust.
 Identities = 14/22 (63%), Positives = 18/22 (81%)
 Frame = -2

Query: 138 TVFAKIDINGDGELSLEEFMEG 159
           T F ++D N DG+LSLEEF+EG
Sbjct: 817 TNFRQMDKNLDGKLSLEEFIEG 752
>08380
          Length = 1236

 Score = 29.6 bits (65), Expect = 0.83,   Method: Compositional matrix adjust.
 Identities = 29/128 (22%), Positives = 54/128 (42%), Gaps = 23/128 (17%)
 Frame = -1

Query: 52  ASQYVEQMFETFDFNKDGYIDFMEY-------------VAALSLVLKGKV-------EQK 91
           A+Q  E++F+  D + +G + + EY             VA+  +V   ++       E+ 
Sbjct: 774 ATQENEEIFKHLDPDNNGKVHWKEYYVHFLLAKGYKQDVASRHVVDYDZIQLDPDAKEEI 595

Query: 92  LRWYFKLYDVDG---NGCIDRDELLTIIRAIRTINPWSDSSMSAEEFTDTVFAKIDINGD 148
           +R+ F+  D DG   +  + R+E ++             S  +     + +   ID NGD
Sbjct: 594 IRYKFRWSDADGEPMDNELTREEFMSFRHP-------EQSEKTLNNMVNGILGGIDTNGD 436

Query: 149 GELSLEEF 156
           G ++ EEF
Sbjct: 435 GVVTEEEF 412
>38338
          Length = 463

 Score = 28.9 bits (63), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 18/61 (29%), Positives = 33/61 (54%)
 Frame = -2

Query: 91  KLRWYFKLYDVDGNGCIDRDELLTIIRAIRTINPWSDSSMSAEEFTDTVFAKIDINGDGE 150
           + +  F L+D DG+G I   EL T++R++   NP      +  E  D +  ++D +G+G 
Sbjct: 165 EFKEAFSLFDKDGDGTITTKELGTVMRSLGQ-NP------TEAELQDMI-NEVDADGNGT 10

Query: 151 L 151
           +
Sbjct: 9   I 7
>04643
          Length = 1881

 Score = 28.9 bits (63), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 17/54 (31%), Positives = 32/54 (59%)
 Frame = +2

Query: 104 NGCIDRDELLTIIRAIRTINPWSDSSMSAEEFTDTVFAKIDINGDGELSLEEFM 157
           +GC+  DE+   +RA+      +   MS EE  D + +K D +G+G+++ +EF+
Sbjct: 2   SGCLCADEIKAHVRAL------TGDDMS-EEALDNLVSKSDADGNGKINYKEFL 142
>17977
          Length = 445

 Score = 27.3 bits (59), Expect = 4.3,   Method: Compositional matrix adjust.
 Identities = 11/26 (42%), Positives = 19/26 (73%)
 Frame = +3

Query: 56  VEQMFETFDFNKDGYIDFMEYVAALS 81
           +EQ+F+  D N+DG ID++E+   L+
Sbjct: 333 LEQVFDYCDENRDGQIDYLEFANFLN 410
>17484
          Length = 471

 Score = 27.3 bits (59), Expect = 4.5,   Method: Compositional matrix adjust.
 Identities = 21/84 (25%), Positives = 43/84 (51%), Gaps = 2/84 (2%)
 Frame = -3

Query: 75  EYVAALSLVLKGKVEQ--KLRWYFKLYDVDGNGCIDRDELLTIIRAIRTINPWSDSSMSA 132
           E++  +   +KG  E+  ++R  F+ +D +G+G I   EL   +   +     SD+ +  
Sbjct: 322 EFLPLIVGRMKGGSEKDKEMRDAFRAFDQNGDGVISISELRQAM--AKMGQKLSDADV-- 155

Query: 133 EEFTDTVFAKIDINGDGELSLEEF 156
               +++   +D +GDG ++ EEF
Sbjct: 154 ----ESIIRDVDKDGDGFVNYEEF 95
>24587
          Length = 2023

 Score = 26.6 bits (57), Expect = 7.5,   Method: Compositional matrix adjust.
 Identities = 12/34 (35%), Positives = 16/34 (47%), Gaps = 2/34 (5%)
 Frame = -3

Query: 13   LSSTECHQWYKKFMTECPSG--QLTLYEFRQFFG 44
            L+S  C QWY++   +   G  QL    F   FG
Sbjct: 1691 LNSVNCKQWYQRXXVQLRPGNNQLXYSRFTSRFG 1590
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|93004085|ref|NP_032813.3| pericentrin [Mus musculus]
         (2916 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

12039                                                                  57   2e-07
00197                                                                  31   7.0  
22195                                                                  31   7.4  
>12039
          Length = 1726

 Score = 56.6 bits (135), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 43/139 (30%), Positives = 64/139 (46%), Gaps = 4/139 (2%)
 Frame = +2

Query: 2711 KMEKLYLHYLRAESFRKAXXXXXXXXXXXXXXFQDSEQETLSMIAHLGVFPSKADKKITM 2770
            KM+++Y  YLRAESFRKA              +QDSEQETL++IA +G  PS +   + M
Sbjct: 719  KMQRIYGKYLRAESFRKALVYQKKYLLLLLGGYQDSEQETLAVIATMGGQPS-STLDLAM 895

Query: 2771 SRP----FTKFRTAXXXXXXXXXXXXXXKKWQEVDRKGALVHPKSTRHGHRTSQRQRSPS 2826
             R     ++ FR+A              ++W+   R G+ V         R +Q+    +
Sbjct: 896  RRRHHRLYSMFRSAARMVVAIFRMKYLVRRWKRAMRIGSPVVSG------RINQQYGYVA 1057

Query: 2827 GPRASLPTRDTSSGPTKAS 2845
               A  P  D   GPT ++
Sbjct: 1058 TASAFSPVNDAERGPTNSA 1114
>00197
          Length = 1145

 Score = 31.2 bits (69), Expect = 7.0,   Method: Composition-based stats.
 Identities = 20/72 (27%), Positives = 35/72 (48%), Gaps = 3/72 (4%)
 Frame = -2

Query: 2809 PKSTRHGHRTSQRQRSPSGPRASLPTRDTSSGP---TKASRHSPRSAAAGSPGKERSTST 2865
            P++        +R RS S  +A+ P + +SS P   TK S+  PRS + G     ++   
Sbjct: 844  PEARPKPKTAKRRSRSVSPDKAAKPKKRSSSDPSKKTKGSKPKPRSTSPGKAPVSKAKKR 665

Query: 2866 PSSRLERSLTAS 2877
            P++R    +T +
Sbjct: 664  PTARSASPVTKT 629
>22195
          Length = 1195

 Score = 30.8 bits (68), Expect = 7.4,   Method: Composition-based stats.
 Identities = 20/67 (29%), Positives = 35/67 (52%), Gaps = 1/67 (1%)
 Frame = +1

Query: 2818 TSQRQRSPSGPRASLPTRDTSSGPTKASRHSPRSAAAGSPGKERS-TSTPSSRLERSLTA 2876
            T+ R+ +  GP A+ P   +++G  + +  SPR A +  P   +S  +TPS+      +A
Sbjct: 391  TAMRRPATDGPPATPPNAGSATGTGRVTPRSPRIARSPRPLSRKSPPATPST------SA 552

Query: 2877 SQDPEHS 2883
              +PE S
Sbjct: 553  RNEPEKS 573
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|40789282|ref|NP_034059.2| procollagen, type XVIII,
alpha 1 isoform 2 [Mus musculus]
         (1315 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

17689                                                                  55   3e-07
26781                                                                  40   0.007
>17689
          Length = 492

 Score = 54.7 bits (130), Expect = 3e-07,   Method: Composition-based stats.
 Identities = 27/82 (32%), Positives = 43/82 (52%)
 Frame = -3

Query: 136 ASQTQTGASFRLPAFVGQWTHFALSVDGGSVALYVDCEEFQRVPFARASQGLELERGAGL 195
           A Q+   A+F +P  V +W   A  V    + LY +C+E+ +  + R  + L+ E G+ L
Sbjct: 325 AEQSDVIANFTVPTMVHRWNKLAFKVLRDRIVLYYNCQEYDQSYWFRTVENLDFEPGSSL 146

Query: 196 FVGQAGTADPDKFQGMISELKV 217
           ++GQAG      FQ  IS  +V
Sbjct: 145 YIGQAGP----NFQRTISSFQV 92
>26781
          Length = 446

 Score = 40.0 bits (92), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 23/37 (62%), Positives = 27/37 (72%)
 Frame = -2

Query: 613 GSPGLKGDPGVAGLPGAKGEVGADGAQGIPGPPGREG 649
           G PGL+G+PGV GLPG  GE GA G  G+PG PG +G
Sbjct: 115 GLPGLQGNPGVPGLPGRDGEPGAPGPDGLPGLPGLKG 5
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|39652626|ref|NP_035924.2| bisphosphate
3'-nucleotidase 1 [Mus musculus]
         (308 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

25328                                                                  52   4e-07
>25328
          Length = 468

 Score = 51.6 bits (122), Expect = 4e-07,   Method: Compositional matrix adjust.
 Identities = 27/63 (42%), Positives = 36/63 (57%)
 Frame = -3

Query: 232 KASAYVFASPGCKKWDTCAPEVILHAVGGKLTDIHGNALQYNKEVKHMNSAGVLAALRNY 291
            A+AY+  S   KKWD CA E ILHA+GG +T I G  + Y      +N  G+LA L  +
Sbjct: 466 NATAYLHTSK-IKKWDICAGEAILHALGGAMTAIDGKPISYGSHDSAVNMDGLLATLGQH 290

Query: 292 EYY 294
           + Y
Sbjct: 289 DEY 281
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6677693|ref|NP_033064.1| recoverin [Mus musculus]
         (202 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

26019                                                                  50   4e-07
00167                                                                  38   0.003
07198                                                                  35   0.019
14945                                                                  34   0.051
07678                                                                  33   0.065
22063                                                                  32   0.12 
01128                                                                  32   0.12 
01041                                                                  31   0.30 
04968                                                                  31   0.35 
14594                                                                  30   0.94 
38338                                                                  30   0.98 
08664                                                                  29   1.2  
01491                                                                  27   4.5  
01019                                                                  27   4.6  
05230                                                                  27   4.6  
26849                                                                  27   5.1  
32088                                                                  27   5.2  
17484                                                                  27   6.9  
>26019
          Length = 1561

 Score = 50.4 bits (119), Expect = 4e-07,   Method: Compositional matrix adjust.
 Identities = 27/87 (31%), Positives = 46/87 (52%), Gaps = 1/87 (1%)
 Frame = +2

Query: 41  SGRITRQEFESIYSKFFPDSDPKAYAQHVFRSFDANSDGTLDFKEYVIAL-HMTTAGKPT 99
           SG ++  EF S+     P+       Q V   FD + +G +DFKE++  +   +  G   
Sbjct: 140 SGSLSIDEFMSL-----PELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGISQFSVKGDKE 304

Query: 100 QKLEWAFSLYDVDGNGTISKNEVLEIV 126
            KL +AF +YD+D +G IS  E+ +++
Sbjct: 305 SKLRFAFKIYDMDKDGYISNGELFQVL 385
>00167
          Length = 2176

 Score = 37.7 bits (86), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 19/55 (34%), Positives = 34/55 (61%)
 Frame = +3

Query: 69  VFRSFDANSDGTLDFKEYVIALHMTTAGKPTQKLEWAFSLYDVDGNGTISKNEVL 123
           VFR FD +  GTLDF+E+++AL         + ++ AF+  D  G+G I+ ++++
Sbjct: 855 VFRRFDKDGTGTLDFEEFLLALRPKMNEFRRKLVKKAFAKMDKTGDGIITADDLV 1019
>07198
          Length = 1675

 Score = 35.0 bits (79), Expect = 0.019,   Method: Compositional matrix adjust.
 Identities = 23/85 (27%), Positives = 41/85 (48%)
 Frame = -3

Query: 42  GRITRQEFESIYSKFFPDSDPKAYAQHVFRSFDANSDGTLDFKEYVIALHMTTAGKPTQK 101
           G +  +E+   ++ F P+S P+   +   R  D N DGT+  +E+   +     G     
Sbjct: 437 GSLNSKEY---FAFFMPNSFPQLELERFMRQSDKNKDGTISMEEF---MPEGATGDTRTS 276

Query: 102 LEWAFSLYDVDGNGTISKNEVLEIV 126
            E +F  YD D +G++S  E +E +
Sbjct: 275 SEESFKNYDKDKDGSLSLEEAMEWI 201

 Score = 29.6 bits (65), Expect = 0.76,   Method: Compositional matrix adjust.
 Identities = 22/55 (40%), Positives = 30/55 (54%)
 Frame = -3

Query: 69  VFRSFDANSDGTLDFKEYVIALHMTTAGKPTQKLEWAFSLYDVDGNGTISKNEVL 123
           VF + DAN DG+L+ KEY  A  M  +  P  +LE      D + +GTIS  E +
Sbjct: 467 VFDAADANKDGSLNSKEY-FAFFMPNSF-PQLELERFMRQSDKNKDGTISMEEFM 309
>14945
          Length = 1337

 Score = 33.9 bits (76), Expect = 0.051,   Method: Compositional matrix adjust.
 Identities = 18/60 (30%), Positives = 31/60 (51%)
 Frame = +1

Query: 67  QHVFRSFDANSDGTLDFKEYVIALHMTTAGKPTQKLEWAFSLYDVDGNGTISKNEVLEIV 126
           +  F  FDA+  GT+D KE  +A+         ++++   +  D +G GTI  N+ L I+
Sbjct: 121 REAFDLFDADGSGTIDAKELKVAMRALGFEPKKEEIKKMIAEIDKEGTGTIDFNDFLTIM 300
>07678
          Length = 958

 Score = 33.5 bits (75), Expect = 0.065,   Method: Compositional matrix adjust.
 Identities = 15/52 (28%), Positives = 27/52 (51%)
 Frame = +1

Query: 67  QHVFRSFDANSDGTLDFKEYVIALHMTTAGKPTQKLEWAFSLYDVDGNGTIS 118
           Q +F  FD +  GT+DF E+++ L    +      ++ AF   D  G+G ++
Sbjct: 439 QEMFTCFDKDZSGTIDFDEFLVKLRPPMSQMRKDLIQRAFQKLDKTGDGVVT 594
>22063
          Length = 688

 Score = 32.3 bits (72), Expect = 0.12,   Method: Compositional matrix adjust.
 Identities = 18/58 (31%), Positives = 30/58 (51%)
 Frame = +3

Query: 69  VFRSFDANSDGTLDFKEYVIALHMTTAGKPTQKLEWAFSLYDVDGNGTISKNEVLEIV 126
            F  FDA+  GT+D KE  +A+         ++++   +  D +G GTI  N+ L I+
Sbjct: 186 AFDLFDADGSGTIDAKELKVAMRALGFEPKKEEIKKMIAEIDKEGTGTIDFNDFLTIM 359
>01128
          Length = 802

 Score = 32.3 bits (72), Expect = 0.12,   Method: Compositional matrix adjust.
 Identities = 16/56 (28%), Positives = 25/56 (44%)
 Frame = -3

Query: 1   MGNSKSGALSKEILEELQLNTKFTEEELSAWYQSFLKECPSGRITRQEFESIYSKF 56
           +   + G+L   +     +   FT        QS LK+C  G + R+ FES+  KF
Sbjct: 335 LSQXRQGSLVSMVTHHTHVTAVFT--------QSSLKQCSCGHVCRRFFESVSHKF 192
>01041
          Length = 1761

 Score = 31.2 bits (69), Expect = 0.30,   Method: Compositional matrix adjust.
 Identities = 20/64 (31%), Positives = 30/64 (46%)
 Frame = -3

Query: 63   KAYAQHVFRSFDANSDGTLDFKEYVIALHMTTAGKPTQKLEWAFSLYDVDGNGTISKNEV 122
            KA A  VF   D NSD  +DF E  +  H+                +D+D +GT+S++E 
Sbjct: 1432 KAQAVVVFEELDVNSDSVVDFIE--MQRHLE---------------FDIDSDGTVSEDEA 1304

Query: 123  LEIV 126
             E +
Sbjct: 1303 REYL 1292
>04968
          Length = 704

 Score = 30.8 bits (68), Expect = 0.35,   Method: Compositional matrix adjust.
 Identities = 20/59 (33%), Positives = 28/59 (47%)
 Frame = +1

Query: 63  KAYAQHVFRSFDANSDGTLDFKEYVIALHMTTAGKPTQKLEWAFSLYDVDGNGTISKNE 121
           KA A  VF   D NSD  +DF E              + LE     +D+D +GT+S++E
Sbjct: 37  KAQAVVVFEELDVNSDSVVDFIEM------------QRHLE-----FDIDSDGTVSEDE 162
>14594
          Length = 1014

 Score = 29.6 bits (65), Expect = 0.94,   Method: Compositional matrix adjust.
 Identities = 21/59 (35%), Positives = 32/59 (54%), Gaps = 2/59 (3%)
 Frame = +3

Query: 70  FRSFDANSDGTLDFKEYVIALHMTTAGK-PTQ-KLEWAFSLYDVDGNGTISKNEVLEIV 126
           F  FD + DGT+   E  +   M + G+ PT+ +L+   +  D DGNGTI   E L ++
Sbjct: 459 FSLFDKDGDGTITTSE--LGTVMRSLGQNPTENELQDMINEVDADGNGTIDFEEFLHMM 629

 Score = 29.3 bits (64), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 21/90 (23%), Positives = 45/90 (50%), Gaps = 2/90 (2%)
 Frame = +3

Query: 41  SGRITRQEFESIYSKFFPDSDPKAYAQHVFRSFDANSDGTLDFKEYVIALHMTTAGK--P 98
           +G I  +EF  + ++   D+D +   +  FR FD + +G +   E  +   MT  G+   
Sbjct: 591 NGTIDFEEFLHMMARKMKDTDCEEELREAFRVFDKDGNGYISAAE--LRHVMTNLGEKLT 764

Query: 99  TQKLEWAFSLYDVDGNGTISKNEVLEIVMA 128
            ++++      D+DG+G ++  E + ++ A
Sbjct: 765 DEEVDEMIKEADLDGDGMVNYEEFVTMMTA 854

 Score = 28.5 bits (62), Expect = 1.8,   Method: Compositional matrix adjust.
 Identities = 11/25 (44%), Positives = 20/25 (80%)
 Frame = +3

Query: 105 AFSLYDVDGNGTISKNEVLEIVMAI 129
           AFSL+D DG+GTI+ +E+  ++ ++
Sbjct: 456 AFSLFDKDGDGTITTSELGTVMRSL 530
>38338
          Length = 463

 Score = 29.6 bits (65), Expect = 0.98,   Method: Compositional matrix adjust.
 Identities = 20/51 (39%), Positives = 29/51 (56%), Gaps = 2/51 (3%)
 Frame = -2

Query: 69  VFRSFDANSDGTLDFKEYVIALHMTTAGK-PTQ-KLEWAFSLYDVDGNGTI 117
            F  FD + DGT+  KE  +   M + G+ PT+ +L+   +  D DGNGTI
Sbjct: 153 AFSLFDKDGDGTITTKE--LGTVMRSLGQNPTEAELQDMINEVDADGNGTI 7

 Score = 28.5 bits (62), Expect = 2.1,   Method: Compositional matrix adjust.
 Identities = 11/25 (44%), Positives = 19/25 (76%)
 Frame = -2

Query: 105 AFSLYDVDGNGTISKNEVLEIVMAI 129
           AFSL+D DG+GTI+  E+  ++ ++
Sbjct: 153 AFSLFDKDGDGTITTKELGTVMRSL 79
>08664
          Length = 1295

 Score = 29.3 bits (64), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 19/62 (30%), Positives = 29/62 (46%)
 Frame = +2

Query: 12  EILEELQLNTKFTEEELSAWYQSFLKECPSGRITRQEFESIYSKFFPDSDPKAYAQHVFR 71
           E  EE++L  +   +E     +  LKECPSG       +        D +PKAY + + +
Sbjct: 224 ERREEIRLLKRLKRQEKETRLERLLKECPSG------VDFSVDDLKGDFNPKAYDRMMKK 385

Query: 72  SF 73
           SF
Sbjct: 386 SF 391
>01491
          Length = 1707

 Score = 27.3 bits (59), Expect = 4.5,   Method: Compositional matrix adjust.
 Identities = 11/35 (31%), Positives = 20/35 (57%)
 Frame = +2

Query: 105 AFSLYDVDGNGTISKNEVLEIVMAIFKMIKPEDVK 139
            F L+D  GNGT+S  E+  +  ++   ++ E +K
Sbjct: 143 TFHLFDKKGNGTVSTKELANVFKSLGLQVEDEKLK 247
>01019
          Length = 1705

 Score = 27.3 bits (59), Expect = 4.6,   Method: Compositional matrix adjust.
 Identities = 12/36 (33%), Positives = 21/36 (58%)
 Frame = +1

Query: 103 EWAFSLYDVDGNGTISKNEVLEIVMAIFKMIKPEDV 138
           EW   ++D DGNG IS  E+  ++  + + +  E+V
Sbjct: 28  EWPLLVFDKDGNGFISAAELRHVMTNLGEKLTDEEV 135
>05230
          Length = 843

 Score = 27.3 bits (59), Expect = 4.6,   Method: Compositional matrix adjust.
 Identities = 37/150 (24%), Positives = 62/150 (41%), Gaps = 1/150 (0%)
 Frame = -2

Query: 32  YQSFLKECPSGRITRQEFESIYSKF-FPDSDPKAYAQHVFRSFDANSDGTLDFKEYVIAL 90
           +QS       GR+   EF  + +    P++  +  A+ +F          L  +EY+  +
Sbjct: 842 FQSMGDVLQDGRLNLFEFTRLMTLLGLPNA--QEAAKVLFDKQTKVERDRLRMEEYISIM 669

Query: 91  HMTTAGKPTQKLEWAFSLYDVDGNGTISKNEVLEIVMAIFKMIKPEDVKLLPDDENTPEK 150
              +    T      F+ +D DG+G  S+ +V+E +  I   I             TP+ 
Sbjct: 668 SDASVDMKTNMWRKLFAQFDTDGSGWASREDVIEGLENIGITI-------------TPDL 528

Query: 151 RAEKIWAFFGKKEDDKLTEEEFIEGTLANK 180
           RA KI A  G K D K+   +F+   L +K
Sbjct: 527 RA-KIKAMDGNK-DGKINYADFLRMQLLHK 444
>26849
          Length = 649

 Score = 26.9 bits (58), Expect = 5.1,   Method: Compositional matrix adjust.
 Identities = 18/59 (30%), Positives = 28/59 (47%), Gaps = 3/59 (5%)
 Frame = +2

Query: 68  HVFRSFDANSDGTL---DFKEYVIALHMTTAGKPTQKLEWAFSLYDVDGNGTISKNEVL 123
             FR  D +    L   +FK+ ++ +H+         +E  F  +D DGNGTI+  E L
Sbjct: 179 RAFRVMDKDGSKVLSLEEFKKGILDMHIDI---NEADIEDMFYRFDNDGNGTINMTEFL 346
>32088
          Length = 1928

 Score = 26.9 bits (58), Expect = 5.2,   Method: Compositional matrix adjust.
 Identities = 17/63 (26%), Positives = 27/63 (42%)
 Frame = +1

Query: 59  DSDPKAYAQHVFRSFDANSDGTLDFKEYVIALHMTTAGKPTQKLEWAFSLYDVDGNGTIS 118
           D D     + VF S D +++G +   E   A        P  +L    S YD  G+G ++
Sbjct: 928 DEDQLTELRSVFDSIDDDNNGHISXGELDSAFRAVGLNIPGYELRTIMSKYDASGDGRLN 1107

Query: 119 KNE 121
            +E
Sbjct: 1108MDE 1116
>17484
          Length = 471

 Score = 26.6 bits (57), Expect = 6.9,   Method: Compositional matrix adjust.
 Identities = 10/21 (47%), Positives = 14/21 (66%)
 Frame = -1

Query: 109 YDVDGNGTISKNEVLEIVMAI 129
           YD DGNG I++NE   +V  +
Sbjct: 465 YDQDGNGKITRNEFRSVVRML 403
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|7949125|ref|NP_058039.1| RUN domain containing 3A
[Mus musculus]
         (446 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

07440                                                                  52   5e-07
34637                                                                  30   2.1  
>07440
          Length = 656

 Score = 52.0 bits (123), Expect = 5e-07,   Method: Compositional matrix adjust.
 Identities = 43/174 (24%), Positives = 76/174 (43%), Gaps = 8/174 (4%)
 Frame = -3

Query: 27  ERRNLITVCRFSVKTLLEKYTAEPIDD----SSEEFVNFAAILEQILSHRFKACAPAGPA 82
           ER  L      S+K+L +K   E +D     S+E   N  + LE +  H  K    +   
Sbjct: 573 EREKLTQQFHRSLKSLQQK---EHVDGATIVSNESSNNLCSALEAVFLHGLKDNVMSKLV 403

Query: 83  SW---FSSDGQRGFWDYIRLACSKVPNNCVSSIENMENISTARAKGRAWIRVALMEKRMS 139
           S+     ++ +  FW  ++    K   +    +  +  I++     RAW+R+A+ +  M+
Sbjct: 402 SYAQGVQTEVRLNFWHVVKRFTHK---DVXVQLRQLSQINSDIGLCRAWVRLAVNDGLMA 232

Query: 140 EYITTALRDNRTTRRFYDSGAIML-REEATVLTGMLIGLSAIDFSFCLKGEVLD 192
            Y+ +   D +    FY S A +L  E+  +L   L GL  ++F   L   VL+
Sbjct: 231 SYLASMTADTKAMVGFYQSWAYLLDYEQPEILRNHLTGLMGLNFHLSLNSSVLN 70
>34637
          Length = 796

 Score = 30.0 bits (66), Expect = 2.1,   Method: Compositional matrix adjust.
 Identities = 15/26 (57%), Positives = 18/26 (69%)
 Frame = -1

Query: 164 REEATVLTGMLIGLSAIDFSFCLKGE 189
           R+E TVLT +L G S +  SF LKGE
Sbjct: 361 RKEETVLTRLLTGHSYLTHSFLLKGE 284
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|19527026|ref|NP_598568.1| leucine rich repeat
containing 59 [Mus musculus]
         (307 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

05532                                                                  51   6e-07
34576                                                                  48   5e-06
19531                                                                  46   2e-05
20480                                                                  44   7e-05
09309                                                                  37   0.014
17298                                                                  32   0.22 
20775                                                                  32   0.42 
30747                                                                  31   0.66 
05398                                                                  27   8.6  
>05532
          Length = 1607

 Score = 50.8 bits (120), Expect = 6e-07,   Method: Compositional matrix adjust.
 Identities = 30/63 (47%), Positives = 39/63 (61%)
 Frame = +3

Query: 44  LDLSCNKLSTLPSDFCGLTHLVKLDLSKNKLQQLPADFGRLVNLQHLDLLNNRLVTLPVS 103
           LDLS N+LS+LPS+   LT L +L L  N+L  LP + GRL  LQ+LD+  N L    + 
Sbjct: 261 LDLSSNQLSSLPSEIGDLTELRELLLYNNQLTSLPFELGRLFQLQNLDIKGNPLSQDYMH 440

Query: 104 FAQ 106
           F Q
Sbjct: 441 FYQ 449

 Score = 48.9 bits (115), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 31/85 (36%), Positives = 44/85 (51%)
 Frame = +3

Query: 22  LSLSDLNEVPVKELAALPKATVLDLSCNKLSTLPSDFCGLTHLVKLDLSKNKLQQLPADF 81
           +++S L      EL      T L L+ N+L  +      L HLV LDLS N+L  LP++ 
Sbjct: 126 ITISGLVRNISPELFRFQHLTCLYLNDNRLDHISPHVSQLHHLVCLDLSSNQLSSLPSEI 305

Query: 82  GRLVNLQHLDLLNNRLVTLPVSFAQ 106
           G L  L+ L L NN+L +LP    +
Sbjct: 306 GDLTELRELLLYNNQLTSLPFELGR 380
>34576
          Length = 1496

 Score = 47.8 bits (112), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 31/81 (38%), Positives = 44/81 (54%)
 Frame = +2

Query: 15  LDGNELDLSLSDLNEVPVKELAALPKATVLDLSCNKLSTLPSDFCGLTHLVKLDLSKNKL 74
           LDGN        L+E+P +EL  L K T L L  N     P   C +T L  LDLS NK+
Sbjct: 275 LDGN-------SLHEIP-QELGTLKKLTHLSLGRNAFKEFPRPACSITSLEILDLSDNKI 430

Query: 75  QQLPADFGRLVNLQHLDLLNN 95
            ++P+D  +L++L+ L +  N
Sbjct: 431 TEIPSDIAQLLSLRELYMKKN 493

 Score = 40.0 bits (92), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 29/82 (35%), Positives = 40/82 (48%)
 Frame = +2

Query: 20  LDLSLSDLNEVPVKELAALPKATVLDLSCNKLSTLPSDFCGLTHLVKLDLSKNKLQQLPA 79
           LDLS + + E+P  ++A L     L +  N +S   ++ C L  L   D S N L  LP 
Sbjct: 407 LDLSDNKITEIP-SDIAQLLSLRELYMKKNAVSVFCAELCALQKLQMADFSNNGLLDLPE 583

Query: 80  DFGRLVNLQHLDLLNNRLVTLP 101
           +   L  LQ LDL NN+    P
Sbjct: 584 EVSVLGCLQELDLSNNQFFEFP 649

 Score = 38.9 bits (89), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 24/59 (40%), Positives = 33/59 (55%)
 Frame = +2

Query: 43  VLDLSCNKLSTLPSDFCGLTHLVKLDLSKNKLQQLPADFGRLVNLQHLDLLNNRLVTLP 101
           +LDLS NK++ +PSD   L  L +L + KN +    A+   L  LQ  D  NN L+ LP
Sbjct: 404 ILDLSDNKITEIPSDIAQLLSLRELYMKKNAVSVFCAELCALQKLQMADFSNNGLLDLP 580
>19531
          Length = 415

 Score = 45.8 bits (107), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 28/66 (42%), Positives = 41/66 (62%)
 Frame = -2

Query: 35  LAALPKATVLDLSCNKLSTLPSDFCGLTHLVKLDLSKNKLQQLPADFGRLVNLQHLDLLN 94
           LA LP  TVLD+  N L +LP+    L +L KL++S N+L +LP+  GRL NL  +   +
Sbjct: 315 LAQLPALTVLDVHDNHLQSLPNALGELENLQKLNISHNQLVELPSCIGRLSNLVSVHAEH 136

Query: 95  NRLVTL 100
           N+L  +
Sbjct: 135 NKLTLI 118
>20480
          Length = 638

 Score = 43.9 bits (102), Expect = 7e-05,   Method: Compositional matrix adjust.
 Identities = 25/68 (36%), Positives = 38/68 (55%)
 Frame = -1

Query: 38  LPKATVLDLSCNKLSTLPSDFCGLTHLVKLDLSKNKLQQLPADFGRLVNLQHLDLLNNRL 97
           LPK  +LDLS N +  + S+  GL  L +L L+ NK++ +P   G +  L+ L +  NRL
Sbjct: 437 LPKLQILDLSNNDIEAVSSELSGLQTLRQLILNGNKMEAIPGSIGFMKELRVLGVNENRL 258

Query: 98  VTLPVSFA 105
             +P S  
Sbjct: 257 REVPDSIG 234
>09309
          Length = 1508

 Score = 36.6 bits (83), Expect = 0.014,   Method: Compositional matrix adjust.
 Identities = 28/78 (35%), Positives = 42/78 (53%), Gaps = 1/78 (1%)
 Frame = +3

Query: 19  ELDLSLSDLNEVPVKELAALPKATVLDLSCNKLSTL-PSDFCGLTHLVKLDLSKNKLQQL 77
           E+ LS +   E+P + L  L K  +L L+ N++ST+ PS    L  L  LDL  N + Q+
Sbjct: 654 EVILSCNRFTEIP-QALYELKKLEILFLNDNQVSTIEPSGLQRLGVLATLDLQNNNISQV 830

Query: 78  PADFGRLVNLQHLDLLNN 95
           P + G   +L+ L L  N
Sbjct: 831 PPELGNCTSLRSLQLGGN 884

 Score = 34.7 bits (78), Expect = 0.055,   Method: Compositional matrix adjust.
 Identities = 20/45 (44%), Positives = 26/45 (57%)
 Frame = +3

Query: 61  LTHLVKLDLSKNKLQQLPADFGRLVNLQHLDLLNNRLVTLPVSFA 105
           L+ L  LD+  NKL +LP +   L NL+ LDL NN +  LP S  
Sbjct: 15  LSTLNFLDVRDNKLAKLPDEITLLENLERLDLSNNDISMLPYSLG 149

 Score = 34.7 bits (78), Expect = 0.056,   Method: Compositional matrix adjust.
 Identities = 20/58 (34%), Positives = 33/58 (56%)
 Frame = +3

Query: 43  VLDLSCNKLSTLPSDFCGLTHLVKLDLSKNKLQQLPADFGRLVNLQHLDLLNNRLVTL 100
            LD+  NKL+ LP +   L +L +LDLS N +  LP   G + +L+ + L  N + ++
Sbjct: 30  FLDVRDNKLAKLPDEITLLENLERLDLSNNDISMLPYSLGTINSLKSVILDGNPMKSI 203

 Score = 33.1 bits (74), Expect = 0.16,   Method: Compositional matrix adjust.
 Identities = 23/82 (28%), Positives = 38/82 (46%)
 Frame = +3

Query: 20  LDLSLSDLNEVPVKELAALPKATVLDLSCNKLSTLPSDFCGLTHLVKLDLSKNKLQQLPA 79
           +++S +   ++P      +   T L++  NKL+ L  D      L  LDL  N L  LPA
Sbjct: 447 VNISKNQFTQLPSNLFLLVNSLTELNMGFNKLTGLSPDIGLFLKLTCLDLRNNGLSSLPA 626

Query: 80  DFGRLVNLQHLDLLNNRLVTLP 101
           +   +  L+ + L  NR   +P
Sbjct: 627 ELCSMQALREVILSCNRFTEIP 692
>17298
          Length = 476

 Score = 32.3 bits (72), Expect = 0.22,   Method: Compositional matrix adjust.
 Identities = 15/49 (30%), Positives = 29/49 (59%)
 Frame = +3

Query: 49  NKLSTLPSDFCGLTHLVKLDLSKNKLQQLPADFGRLVNLQHLDLLNNRL 97
           N ++ +P+D   L HL  L+L+ N++++LP +      L+ L L  N++
Sbjct: 267 NAITDVPADLSSLPHLNCLNLADNQIEELPNELCECTRLKELKLSGNKI 413
>20775
          Length = 1020

 Score = 31.6 bits (70), Expect = 0.42,   Method: Compositional matrix adjust.
 Identities = 20/55 (36%), Positives = 28/55 (50%), Gaps = 2/55 (3%)
 Frame = -3

Query: 54  LPSDFCGLTHLVKLDLSKNKLQQLPADF--GRLVNLQHLDLLNNRLVTLPVSFAQ 106
           L + F     L+ LDLS N L  LP +F  G +++   L L NN    LPV+  +
Sbjct: 613 LNTSFANSVTLINLDLSGNNLSTLPDNFLNGEIID--SLILKNNNFTALPVALTK 455

 Score = 30.8 bits (68), Expect = 0.72,   Method: Compositional matrix adjust.
 Identities = 20/57 (35%), Positives = 29/57 (50%)
 Frame = -3

Query: 44  LDLSCNKLSTLPSDFCGLTHLVKLDLSKNKLQQLPADFGRLVNLQHLDLLNNRLVTL 100
           LDLS N LSTLP +F     +  L L  N    LP    ++ + + LD+  + LV+ 
Sbjct: 574 LDLSGNNLSTLPDNFLNGEIIDSLILKNNNFTALPVALTKVEHXRRLDVSFSALVSF 404
>30747
          Length = 1168

 Score = 30.8 bits (68), Expect = 0.66,   Method: Compositional matrix adjust.
 Identities = 27/72 (37%), Positives = 38/72 (52%)
 Frame = +3

Query: 27  LNEVPVKELAALPKATVLDLSCNKLSTLPSDFCGLTHLVKLDLSKNKLQQLPADFGRLVN 86
           L ++   EL +    + LDLS N ++ L S    L +L +L +S N +Q+L  D  R   
Sbjct: 498 LTKLDTNELLSCVNISTLDLSNNHITNL-SALSYLPNLEELFVSGNSIQKL-TDLHRCKK 671

Query: 87  LQHLDLLNNRLV 98
           L  LDL  NRLV
Sbjct: 672 LSELDLSRNRLV 707
>05398
          Length = 2061

 Score = 27.3 bits (59), Expect = 8.6,   Method: Compositional matrix adjust.
 Identities = 12/31 (38%), Positives = 19/31 (61%), Gaps = 1/31 (3%)
 Frame = +1

Query: 269 TGLHQQPLCTSVNT-IYDNAVQGLRHHEILQ 298
           TGL++ PLC  ++  IY +A   +RH   L+
Sbjct: 256 TGLNESPLCVDLHVLIYTHAYSAIRHTSALE 348
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31542014|ref|NP_084210.2| membrane bound
O-acyltransferase domain containing 7 [Mus musculus]
         (473 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

00476                                                                  52   6e-07
39334                                                                  28   7.0  
23623                                                                  28   7.5  
09955                                                                  28   8.3  
>00476
          Length = 860

 Score = 51.6 bits (122), Expect = 6e-07,   Method: Compositional matrix adjust.
 Identities = 27/86 (31%), Positives = 45/86 (52%), Gaps = 2/86 (2%)
 Frame = +1

Query: 351 LSAYWHGLHPGYYLSFMTIPLCLAAEGYLESALR--RHLSPGGQKAWDWVHWFLKMRAYD 408
           +SA+WHG +PGYY++F T  L + A   +   +R     S   ++ +D + +     A  
Sbjct: 34  VSAFWHGFYPGYYMTFGTAALLVTAARLIRRNVRPWFQTSDLKKEVYDAITFMFARMANV 213

Query: 409 YMCMGFVLLSMADTLRYWASIYFWVH 434
           Y+C  F+ L    TLR + + Y W+H
Sbjct: 214 YICFPFLTLEFMSTLRVYMAQYCWMH 291
>39334
          Length = 432

 Score = 28.1 bits (61), Expect = 7.0,   Method: Compositional matrix adjust.
 Identities = 16/49 (32%), Positives = 23/49 (46%), Gaps = 4/49 (8%)
 Frame = -2

Query: 351 LSAYWHGLHPGYYLSFM----TIPLCLAAEGYLESALRRHLSPGGQKAW 395
           LS    G  P Y++ F+     + +     G L+  LR H  PGG K+W
Sbjct: 218 LSERSQGCSPRYWMMFLIASSNVDMGREDIGILQFILRAHFFPGGSKSW 72
>23623
          Length = 768

 Score = 28.1 bits (61), Expect = 7.5,   Method: Compositional matrix adjust.
 Identities = 20/80 (25%), Positives = 30/80 (37%)
 Frame = -3

Query: 355 WHGLHPGYYLSFMTIPLCLAAEGYLESALRRHLSPGGQKAWDWVHWFLKMRAYDYMCMGF 414
           WHG   GY         C    G         L    ++ +D + +     A  Y+C  F
Sbjct: 754 WHGRTAGY--------CCTMIRGTCGRGSDERLK---KEVYDAITFMFARMANVYICFPF 608

Query: 415 VLLSMADTLRYWASIYFWVH 434
           + L    TLR + + Y W+H
Sbjct: 607 LTLEFMSTLRVYMAQYCWMH 548
>09955
          Length = 1279

 Score = 28.1 bits (61), Expect = 8.3,   Method: Compositional matrix adjust.
 Identities = 19/48 (39%), Positives = 23/48 (47%)
 Frame = -3

Query: 231 LFYMIPVFFAFRMRFYVAWIAAECGCIAAGFGAYPVAAKARAGGGPTL 278
           LFY +   F F     V   A +CG IAA   AYP  +K  AG  P +
Sbjct: 941 LFYCVWYCFQFSYMLRVVSRARQCG-IAAKISAYPQNSKHAAGKTPQV 801
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|7304975|ref|NP_038524.1| cellular retinoic acid
binding protein I [Mus musculus]
         (137 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

14358                                                                  49   6e-07
31753                                                                  37   0.004
>14358
          Length = 996

 Score = 49.3 bits (116), Expect = 6e-07,   Method: Compositional matrix adjust.
 Identities = 33/95 (34%), Positives = 56/95 (58%), Gaps = 4/95 (4%)
 Frame = +1

Query: 42  VEIRQDGDQFYIKTSTTVRTTEINFKVGEGFEE-ETVDGRKCRSLPTWENENKIHCTQTL 100
           +E++ DG +  I+T++T   +E++FK+ E +EE      +K  ++PT+EN  K+  T T 
Sbjct: 7   IEVQDDG-KIVIRTNSTFMKSEVSFKLNEEYEEINPHSKKKFXNMPTYEN-GKLRVTPTP 180

Query: 101 LEG-DGP-KTYWTRELAND-ELILTFGADDVVCTR 132
            E  D P   Y  RE+ +D E+++T   +DV C R
Sbjct: 181 AEPIDVPYPEYXEREITDDGEMLVTLKVEDVXCKR 285
>31753
          Length = 374

 Score = 36.6 bits (83), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 23/68 (33%), Positives = 32/68 (47%), Gaps = 4/68 (5%)
 Frame = -3

Query: 1   MPNFAGTWKMRSSENFDELLKALGVNAMLRKVAVAAASKPHVEIRQ----DGDQFYIKTS 56
           M    G WK+ S +NF+  L A+GV    R  A+   + P   I Q    DGD   I T+
Sbjct: 228 MAALNGKWKLVSVDNFESYLDAVGVQGEFRDKALKLLT-PENNILQDIAIDGDAISITTT 52

Query: 57  TTVRTTEI 64
           T +   E+
Sbjct: 51  TPIAPIEV 28
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|39930567|ref|NP_932148.1| tubulin, gamma complex
associated protein 3 [Mus musculus]
         (905 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

32473                                                                  52   7e-07
07233                                                                  31   2.0  
35557                                                                  30   4.3  
>32473
          Length = 1077

 Score = 52.4 bits (124), Expect = 7e-07,   Method: Compositional matrix adjust.
 Identities = 39/136 (28%), Positives = 71/136 (52%), Gaps = 10/136 (7%)
 Frame = +2

Query: 658 YLRVFNFLWRAKRMEYILTDI-----RKGHMCNAKLLRNMPEFSGVLHQCHILASEMVHF 712
           Y +VF+F+ + KR+ + LTD      R   + NAK  R   +    LH+      EM+HF
Sbjct: 14  YGQVFSFMLQLKRVAWTLTDCWYRLKRDAMVKNAKDSRQFRQLQ--LHR-----QEMLHF 172

Query: 713 IHQMQYYITFEVLECSWDELWNRVQQAQD-----LDHIIAAHEAFLNTITSRCLLDSNSR 767
           +  +Q Y+  ++++ +W EL    QQ+ D     LD +   H  +LN    RCLL+  + 
Sbjct: 173 VRVLQGYMGNQIIQVTWREL----QQSLDHSVHSLDDLKRVHADYLNKALFRCLLNKKAA 340

Query: 768 VLLNQLRAVFDQIIEL 783
            ++++++ +F  I++ 
Sbjct: 341 PIMSKIQNIFCLILKF 388
>07233
          Length = 1497

 Score = 31.2 bits (69), Expect = 2.0,   Method: Compositional matrix adjust.
 Identities = 17/54 (31%), Positives = 27/54 (50%), Gaps = 9/54 (16%)
 Frame = -1

Query: 368 WTYDPKI---------RLKTLAALVDHCQGRKGGELASAVHAYTKTGDPYMKSL 412
           WT  P +          +KTL  + + CQG +  + A A+H  T+ G P +K+L
Sbjct: 525 WTATPSL*TPVAARMXGMKTLVVISNLCQGNQCPQ-APAMHQATQAGSPVLKNL 367
>35557
          Length = 306

 Score = 30.0 bits (66), Expect = 4.3,   Method: Compositional matrix adjust.
 Identities = 12/28 (42%), Positives = 19/28 (67%)
 Frame = +3

Query: 556 HMQAMRRYLLLGQGDFIRHLMDLLKPEL 583
           H+QA+  YL +  GDF ++L D+L  +L
Sbjct: 201 HLQALHSYLFMADGDFAQNLTDILLDKL 284
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|70778802|ref|NP_001020478.1| syntaxin 3 isoform B
[Mus musculus]
         (287 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

08305                                                                  51   7e-07
04022                                                                  28   3.0  
>08305
          Length = 1314

 Score = 50.8 bits (120), Expect = 7e-07,   Method: Compositional matrix adjust.
 Identities = 57/220 (25%), Positives = 102/220 (46%), Gaps = 10/220 (4%)
 Frame = -3

Query: 53   VEEAKKLYSIILSAPIPEPKTKDDLEQLTTEIKKRANNVRNKLKSME----KHIE---ED 105
            V E KKL   ++ +P  +       E +  E+ +    +RN ++ +E    K+I+   +D
Sbjct: 1057 VTELKKLQLDLVYSPFADKDAVSRYEGMIQELTRHXVRIRNDIRQLEGQADKYIDKKPDD 878

Query: 106  EVRSSADLRIRKSQHSVLSRKFVEVMTKYNEAQVDFRERSKGRIQRQLEITGKKTTDEEL 165
            E    A  R+ K Q + L+ +      ++ + Q D+ ++ K R++ QL+  G+  TDE  
Sbjct: 877  E----AFKRVSKQQLNGLTTQLAITTNEFFKCQSDYADKMKERLKGQLQARGESVTDE-- 716

Query: 166  EEMLESGNPAIFTSGIIDSQISKQALSEIEGRHKDIVR---LESSIKELHDMFMDIAMLV 222
              M  SG      S    S +  + L +  G  K       L  S+ +++ +F ++ ++V
Sbjct: 715  R*MKFSGRTRTMCSHRTSS-LKCRMLQKH*GSWKSATMTFLLLKSVTDVNMLFKELNLMV 539

Query: 223  ENQGAMIDRIENNMDQSVGFVERAVADTKKAVKYQSEARR 262
              QG  +D IE N++Q    VE       +AVK Q +A R
Sbjct: 538  SQQGEKLDSIEQNIEQVEVHVESGKEQLTEAVKSQXKAXR 419
>04022
          Length = 1984

 Score = 28.5 bits (62), Expect = 3.0,   Method: Compositional matrix adjust.
 Identities = 16/50 (32%), Positives = 27/50 (54%)
 Frame = +1

Query: 95  LKSMEKHIEEDEVRSSADLRIRKSQHSVLSRKFVEVMTKYNEAQVDFRER 144
           L    K++  DE+    DL +  ++H V  RKF+++  K+NE   D + R
Sbjct: 580 LFGCTKNLSSDEI---LDLIVLLAKHFVYKRKFIKIEPKFNEFLDDLKLR 720
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|94398775|ref|XP_001001617.1| PREDICTED: ubiquitous
tetratricopeptide containing protein RoXaN isoform 1 [Mus musculus]
         (982 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

23484                                                                  53   7e-07
35348                                                                  47   3e-05
08670                                                                  47   4e-05
13560                                                                  44   3e-04
30337                                                                  42   0.001
03857                                                                  42   0.002
17595                                                                  39   0.011
35341                                                                  33   0.72 
14133                                                                  32   1.8  
00391                                                                  30   4.7  
>23484
          Length = 1647

 Score = 52.8 bits (125), Expect = 7e-07,   Method: Compositional matrix adjust.
 Identities = 34/115 (29%), Positives = 55/115 (47%), Gaps = 1/115 (0%)
 Frame = +1

Query: 42  EGNDLFREKDYKQALVQYMEGLNVADYAASDQVALPRELL-CKLHVNRAACYFTMGLYEK 100
           EGNDLF++KDY+ A+  Y EG+             P+ L    L+ NRAA +F +G Y  
Sbjct: 517 EGNDLFKKKDYRLAVDNYXEGIKSNS---------PQRLQNAVLYTNRAAAHFHLGNYRS 669

Query: 101 ALEDSEKALGLDGESIRALFRKARALNELGRHKEAYECSSRCSLALPHDENVTQL 155
           A  D   A     + ++AL R A   +++ +H +         +  P  +++T L
Sbjct: 670 AFNDCFAARKFKPDHLKALVRGAMCCDKMNKHNDTLRWCDAGLMVEPGHKDLTDL 834
>35348
          Length = 627

 Score = 47.4 bits (111), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 33/95 (34%), Positives = 47/95 (49%), Gaps = 2/95 (2%)
 Frame = -2

Query: 43  GNDLFREKDYKQALVQYMEGLNVA--DYAASDQVALPRELLCKLHVNRAACYFTMGLYEK 100
           GND F+   Y +AL  Y EGL++    Y     V L          NRAAC      Y+K
Sbjct: 563 GNDTFKSGQYAEALELYSEGLDICPLKYVQQRSVMLS---------NRAACRIKKEDYQK 411

Query: 101 ALEDSEKALGLDGESIRALFRKARALNELGRHKEA 135
           A+ D  K++ L+   I+A FR+A A  +L +  +A
Sbjct: 410 AVGDCTKSIDLNPAYIKAYFRRADAYEKLEKLDDA 306
>08670
          Length = 1307

 Score = 47.0 bits (110), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 46/145 (31%), Positives = 74/145 (51%), Gaps = 1/145 (0%)
 Frame = +3

Query: 26  EEYEAFLLKLVQNLFAEGNDLFREKDYKQALVQYMEGLNVADYAASDQVAL-PRELLCKL 84
           EE ++ +L+  Q L   GN++ + ++Y  A+  + E            +AL P++   + 
Sbjct: 345 EEVDSTVLRSRQ-LAIRGNEMAQVEEYSAAIQLFTEA-----------IALDPKDF--RF 482

Query: 85  HVNRAACYFTMGLYEKALEDSEKALGLDGESIRALFRKARALNELGRHKEAYECSSRCSL 144
             NR+ CY  +  YEKAL+D+EKA+ L  +  +  FRK RAL  L +  EA E   +   
Sbjct: 483 LGNRSYCYDRLQQYEKALKDAEKAIKLSKDWPKGYFRKGRALAGLCKFSEAEESFLQV-- 656

Query: 145 ALPHDENVTQLGQELAQKLGLRVRK 169
            L  D+N  +  QEL Q   +R R+
Sbjct: 657 -LKLDKNCEEAVQELQQ---VRTRQ 719
>13560
          Length = 978

 Score = 43.9 bits (102), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 28/78 (35%), Positives = 45/78 (57%), Gaps = 3/78 (3%)
 Frame = +1

Query: 63  LNVADYAASD-QVALPR--ELLCKLHVNRAACYFTMGLYEKALEDSEKALGLDGESIRAL 119
           L+V  Y+ SD +VA     +LLC+ ++N AAC    G ++  + +   AL LD  +++AL
Sbjct: 283 LSVLPYSFSDDEVASTSHLQLLCQCYLNLAACQIKSGHHKHVITNCTHALNLDPANVKAL 462

Query: 120 FRKARALNELGRHKEAYE 137
           +R+A A   LG    A+E
Sbjct: 463 YRRASANVNLGNLLHAHE 516
>30337
          Length = 493

 Score = 42.0 bits (97), Expect = 0.001,   Method: Composition-based stats.
 Identities = 31/102 (30%), Positives = 46/102 (45%), Gaps = 4/102 (3%)
 Frame = -1

Query: 38  NLFAEGNDLFREKDYKQALVQY----MEGLNVADYAASDQVALPRELLCKLHVNRAACYF 93
           +L  +GN LF  + Y+ A+  Y    M+  N A Y                  NRA CY 
Sbjct: 325 DLKNQGNKLFAARKYEDAIHCYTKAIMKNPNTATY----------------FTNRALCYI 194

Query: 94  TMGLYEKALEDSEKALGLDGESIRALFRKARALNELGRHKEA 135
            +  +E A +D ++AL LD   ++  F   +AL EL  + EA
Sbjct: 193 KLRNWELASQDCQRALELDRNLVKGHFFLGQALVELAMYDEA 68
>03857
          Length = 1696

 Score = 41.6 bits (96), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 39/152 (25%), Positives = 75/152 (49%), Gaps = 8/152 (5%)
 Frame = +1

Query: 34  KLVQNLFAEGNDLFR-------EKDYKQALVQYMEGLNVADYAASDQ-VALPRELLCKLH 85
           K+V ++   GN LF+        + YK+AL +Y++ L+     + DQ  A+ +EL   + 
Sbjct: 457 KVVLDVKQAGNTLFKAGKFGPANRKYKKAL-RYLQKLDEEQKMSEDQQKAMEKELHIPVS 633

Query: 86  VNRAACYFTMGLYEKALEDSEKALGLDGESIRALFRKARALNELGRHKEAYECSSRCSLA 145
           +N AAC   +  Y +ALE  ++ L  D ++ +A +R+ +A      ++ A     +   A
Sbjct: 634 LNAAACCLKLNKYNEALEYCQEVLEADPDNSKAQYRQGQAHAGNKDYETALASFQKALAA 813

Query: 146 LPHDENVTQLGQELAQKLGLRVRKAYKRPQEL 177
            P D+ +    +   QK+   V +  KR +++
Sbjct: 814 NPDDKGI----KLEIQKVKRTVEEEKKREKQM 897
>17595
          Length = 483

 Score = 38.9 bits (89), Expect = 0.011,   Method: Compositional matrix adjust.
 Identities = 25/69 (36%), Positives = 38/69 (55%)
 Frame = -2

Query: 96  GLYEKALEDSEKALGLDGESIRALFRKARALNELGRHKEAYECSSRCSLALPHDENVTQL 155
           G YE+A+   E+A+ LD +   A+   A +L ELGRH+EA     R        + + QL
Sbjct: 254 GQYEQAVASYERAVSLDNKFSHAMTNAAASLRELGRHREAELFLKRAVDTTADLDAMGQL 75

Query: 156 GQELAQKLG 164
           G+ L Q++G
Sbjct: 74  GR-LYQRMG 51
>35341
          Length = 641

 Score = 32.7 bits (73), Expect = 0.72,   Method: Composition-based stats.
 Identities = 26/75 (34%), Positives = 35/75 (46%)
 Frame = +3

Query: 60  MEGLNVADYAASDQVALPRELLCKLHVNRAACYFTMGLYEKALEDSEKALGLDGESIRAL 119
           ME   VA+   +  + L   L  K ++ RAA    M   + ALED E+ L L+  S +A 
Sbjct: 63  MEKYGVAEVDCTTAITLD-PLYVKAYLRRAAARVGMQRLQPALEDYERVLQLEPNSKQAQ 239

Query: 120 FRKARALNELGRHKE 134
               R   EL R KE
Sbjct: 240 KEVDRLRKELDREKE 284
>14133
          Length = 1330

 Score = 31.6 bits (70), Expect = 1.8,   Method: Composition-based stats.
 Identities = 18/54 (33%), Positives = 28/54 (51%)
 Frame = +2

Query: 541  AKLLKEHQGIFTFLCEICFDSKPRIISKGTKDSPSVCSNLAAKHSFYNNKCLVH 594
            + L+ E +  F F C +C ++K   I +G    P++C+N    HSF     LVH
Sbjct: 1130 SSLIPEMREAF-FKCYVCGNTKTVEIDRGRIAEPTLCTNCNTNHSF----ALVH 1276
>00391
          Length = 1202

 Score = 30.0 bits (66), Expect = 4.7,   Method: Compositional matrix adjust.
 Identities = 17/51 (33%), Positives = 23/51 (45%)
 Frame = +1

Query: 892 LCDRLQKGKACPDGDKCRCAHGQEELNEWLDRREVLKQKLAKARKDMLLCP 942
           LC   ++   C  GDKC+ AHG  EL   L R    K +  +    +  CP
Sbjct: 700 LCRPFEESGHCKYGDKCQFAHGFHELRN-LSRHPKYKTERCRTYHTIGFCP 849
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|94367281|ref|XP_622097.3| PREDICTED: ribosome binding
protein 1 isoform 1 [Mus musculus]
         (1648 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

15632                                                                  54   8e-07
19049                                                                  37   0.097
>15632
          Length = 633

 Score = 53.5 bits (127), Expect = 8e-07,   Method: Compositional matrix adjust.
 Identities = 42/131 (32%), Positives = 67/131 (51%), Gaps = 1/131 (0%)
 Frame = -1

Query: 1245 ETSELKEAMEQQKGKNNDLREKNWKXXXXXXXXXXXXXXXX-RSLTQAKEESEKQLHLAE 1303
            + +ELK  ++ QK KNN+LREKNWK                 +SL  ++E + K +   E
Sbjct: 426  QITELKTQLDAQKQKNNELREKNWKAMEALEKLKSLQQKKLIKSLKASRETTTKAVTEVE 247

Query: 1304 AQTKETLLALLPGLSISAHQNYAEWLQEFKEKGSELLKKPPTLEPSMDIVLKLREAEETQ 1363
               KE L  L P LS+S    + EWL  F+++ ++ L +    E S+    KL + EE  
Sbjct: 246  KADKEALKRLFPALSVSDKLGHKEWLATFEKQAAQQLTQSSKSEKSVSD--KLGQLEEEN 73

Query: 1364 NSLQAECDQYR 1374
            + LQA+ + ++
Sbjct: 72   SRLQADVEVFK 40
>19049
          Length = 963

 Score = 36.6 bits (83), Expect = 0.097,   Method: Compositional matrix adjust.
 Identities = 18/36 (50%), Positives = 25/36 (69%)
 Frame = -1

Query: 1234 ELESQVSCLEKETSELKEAMEQQKGKNNDLREKNWK 1269
            E+E Q    + + +ELK  ++ QK KNN+LREKNWK
Sbjct: 465  EMEIQQRSSQTQITELKTQLDAQKQKNNELREKNWK 358
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|22296603|ref|NP_680087.1| COMM domain containing 3
[Mus musculus]
         (195 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

30943                                                                  49   9e-07
13142                                                                  31   0.28 
14140                                                                  29   1.3  
01400                                                                  27   6.0  
19988                                                                  27   6.4  
>30943
          Length = 317

 Score = 48.5 bits (114), Expect(2) = 9e-07,   Method: Compositional matrix adjust.
 Identities = 25/76 (32%), Positives = 39/76 (51%)
 Frame = -1

Query: 25  FALLLRAAFQSXXXXXXXXXXXXHPYLKQIDPVVLKHCHAAAATCILEAGKHQVDKSTLS 84
           F  L++ A Q              P  K +D  VLK  ++A    +LEA KH +D + + 
Sbjct: 290 FDHLVKKACQGILSDVDRNAVADDPAFKSVDKGVLKAAYSALVALVLEAAKHDMDANGII 111

Query: 85  TYLEDCKFDRERIELF 100
           ++LE+CKF  +RI+ F
Sbjct: 110 SFLEECKFSPDRIQSF 63

 Score = 20.4 bits (41), Expect(2) = 9e-07,   Method: Compositional matrix adjust.
 Identities = 8/14 (57%), Positives = 12/14 (85%)
 Frame = -3

Query: 108 KNSLETLLGSIGRS 121
           K++++ LLGSIG S
Sbjct: 42  KSAIQILLGSIGSS 1
>13142
          Length = 523

 Score = 31.2 bits (69), Expect = 0.28,   Method: Compositional matrix adjust.
 Identities = 11/36 (30%), Positives = 22/36 (61%)
 Frame = -3

Query: 121 SLPHITDVSWRLEYQIKTNQLHKMYRPGYLVTLNVE 156
           SLP + D  WR++ +  ++ + +M  P  +++L VE
Sbjct: 161 SLPKLADFDWRVDVKTASDTVARMSVPTCILSLQVE 54
>14140
          Length = 893

 Score = 28.9 bits (63), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 17/61 (27%), Positives = 32/61 (52%), Gaps = 2/61 (3%)
 Frame = +3

Query: 82  TLSTYLEDCKFDRERIELFCTEYQNNKNSLETLLGSI--GRSLPHITDVSWRLEYQIKTN 139
           TLS YL++CKF R     +  +Y +  N   +L   +  G++L +I   +W++ Y +   
Sbjct: 93  TLSMYLQNCKFYRIIKTDYRRKYYHFLNVTHSLFF*VMGGKNLHNIYKFAWQISYTLSVR 272

Query: 140 Q 140
           +
Sbjct: 273 K 275
>01400
          Length = 1109

 Score = 26.9 bits (58), Expect = 6.0,   Method: Compositional matrix adjust.
 Identities = 11/30 (36%), Positives = 19/30 (63%)
 Frame = +3

Query: 127 DVSWRLEYQIKTNQLHKMYRPGYLVTLNVE 156
           D+   +++    NQ++KMYR  Y+V LN+ 
Sbjct: 840 DIKLTIDHTXGNNQINKMYR--YIVILNIS 923
>19988
          Length = 418

 Score = 26.6 bits (57), Expect = 6.4,   Method: Compositional matrix adjust.
 Identities = 14/29 (48%), Positives = 19/29 (65%), Gaps = 2/29 (6%)
 Frame = -3

Query: 96  RIELFCTE--YQNNKNSLETLLGSIGRSL 122
            +E FC++  +QNN  SL  LLG +G SL
Sbjct: 89  NLEDFCSDL*WQNNLVSLSFLLGKLGNSL 3
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|51491850|ref|NP_001003912.1| Rho guanine nucleotide
exchange factor (GEF) 11 [Mus musculus]
         (1552 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

03831                                                                  53   9e-07
17768                                                                  53   9e-07
38272                                                                  41   0.005
38751                                                                  38   0.040
20073                                                                  37   0.081
07835                                                                  31   3.0  
>03831
          Length = 1143

 Score = 53.1 bits (126), Expect = 9e-07,   Method: Compositional matrix adjust.
 Identities = 36/100 (36%), Positives = 51/100 (51%), Gaps = 5/100 (5%)
 Frame = +3

Query: 19  GDSTPERTSPSHHRQPSDTSETTGLVQR-CVIIQ-KDQHGFGFTV---SGDRIVLVQSVR 73
           G  T  R  P       D  ++  LV R C I++  D +G+GF +    G     +  V 
Sbjct: 51  GKLTCNRYRPWQLINMGDGGDSPTLVPRLCHIVRWSDFNGYGFNLHAEKGKAGQFIGKVD 230

Query: 74  PGGAAMRAGVKEGDRIIKVNGTMVTNSSHLEVVKLIKSGA 113
            G  A  AG+K GDRI++VNGT + N +H +VV  IK+G 
Sbjct: 231 EGSPAEAAGLKAGDRIVEVNGTNIGNENHQQVVGRIKAGG 350

 Score = 46.2 bits (108), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 26/70 (37%), Positives = 36/70 (51%), Gaps = 1/70 (1%)
 Frame = +3

Query: 43  LVQRCVIIQKDQHGFGFTVSGDR-IVLVQSVRPGGAAMRAGVKEGDRIIKVNGTMVTNSS 101
           L   C     D +GF      D+    + SV P   A   G+KEGDRII+VNG  +  ++
Sbjct: 582 LCHLCKWADFDGYGFNLHAEKDKPGQYIGSVDPNSPAETGGLKEGDRIIEVNGENIETTN 761

Query: 102 HLEVVKLIKS 111
           H  V++ IKS
Sbjct: 762 HTAVIQNIKS 791
>17768
          Length = 492

 Score = 53.1 bits (126), Expect = 9e-07,   Method: Composition-based stats.
 Identities = 40/149 (26%), Positives = 70/149 (46%), Gaps = 10/149 (6%)
 Frame = -1

Query: 792 QRMKKENLMPREELSRLFPNLPELIEIHNSWCEAMKKLREEGPIIRDISDL--------- 842
           ++++ E  +   E   +F  L EL  +  ++C+          +++D+SD          
Sbjct: 489 KKVQVEGSLMFAEPQDIFGKLDELCYVSYTFCKDFI-----AALLKDMSDTDFGRTNVLT 325

Query: 843 -MLARFDGPAREELQQVAAQFCSYQSVALELIRTKQRKESRFQLFMQEAESHPQCRRLQL 901
               RF   +++    V   +C   + AL  +  K R+ S F  F +  E   +C+RLQL
Sbjct: 324 KAFQRFSTHSKD--GAVFHTYCINYTNALTYLE-KLRQNSEFAEFERWCEQDARCKRLQL 154

Query: 902 RDLIISEMQRLTKYPLLLENIIKHTAGGT 930
            DL+++ +Q  TK PLLL N+ K+T   T
Sbjct: 153 TDLLVAPIQHCTKLPLLLANVAKYTENKT 67
>38272
          Length = 749

 Score = 40.8 bits (94), Expect = 0.005,   Method: Composition-based stats.
 Identities = 23/57 (40%), Positives = 36/57 (63%), Gaps = 2/57 (3%)
 Frame = +2

Query: 898 RLQLRDLIISEMQRLTKYPLLLENIIKHT--AGGTSEYEKLCRARDQCREILKFVNE 952
           R  L  LII+ +QR+TKY LL+  I++ T  AG  +E   L  A +Q ++++K VN+
Sbjct: 104 RNDLSALIITPVQRITKYVLLINEILRETKRAGLHNEVATLMEAGEQMKDVVKKVND 274
>38751
          Length = 329

 Score = 37.7 bits (86), Expect = 0.040,   Method: Composition-based stats.
 Identities = 24/75 (32%), Positives = 39/75 (52%)
 Frame = +3

Query: 67  VLVQSVRPGGAAMRAGVKEGDRIIKVNGTMVTNSSHLEVVKLIKSGAYVALTLLGSSPSS 126
           ++V  +  G  A + G+  GDRI+ VNGT  T+ +H E V ++++   V +T+     S 
Sbjct: 39  IVVYVIEEGCQAEQQGLNIGDRILDVNGTDFTHLTHAEAVTIMRNAWNVIMTVQPCPESD 218

Query: 127 IGVSGLQQNPSLSGG 141
            G    QQ  +  GG
Sbjct: 219 SGQG--QQYTTGRGG 257
>20073
          Length = 582

 Score = 36.6 bits (83), Expect = 0.081,   Method: Composition-based stats.
 Identities = 21/60 (35%), Positives = 32/60 (53%), Gaps = 5/60 (8%)
 Frame = +3

Query: 56  GFGFTVSGDR----IVLVQSVRPGGAAMRAG-VKEGDRIIKVNGTMVTNSSHLEVVKLIK 110
           G GF V G +     + +  + PGG A R   +K GD+++ VNG  V    H + V+L+K
Sbjct: 3   GLGFNVMGGKEQSSPIYISRIIPGGVADRLNCLKRGDQLLSVNGVSVEGEYHEKAVELLK 182
>07835
          Length = 1848

 Score = 31.2 bits (69), Expect = 3.0,   Method: Compositional matrix adjust.
 Identities = 42/166 (25%), Positives = 62/166 (37%), Gaps = 18/166 (10%)
 Frame = +1

Query: 404 IWNIFLEKNAPLRVKIPEMLQAEIDLRLRNSEDPRSALYEAQEAVMPEIQEQINDYRSKR 463
            W   + +N  L  +    L  ++DLRL    DP++          P+ QE  N  R  R
Sbjct: 340 CWKNVIPRNHTLE*RTRPRLPCDLDLRL*C*TDPKN--------T*PQHQET*NKRRQAR 495

Query: 464 T-------LGLGSLYGEND---------LLDLDGDPLRERQMAEKQLAALGDILSKYEED 507
           T       +G  S  GEN           L  +G   +   MAE+Q +   D+ +K EE+
Sbjct: 496 TKSTSEDVVGTSSGGGENGNAGTAARKFSLTFEGGVNKSSLMAERQTSVASDVSAKSEEE 675

Query: 508 RSAPMDFAVNTYMSHTGIRLRESRPSS--TAEKTQSAPDKDKWLPF 551
                       M         S+P +   + KTQ      +WLPF
Sbjct: 676 VEVEGGGTDEARMEQVKSSSTHSQPITIQKSNKTQ------RWLPF 795
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|124001582|ref|NP_796363.2| melanoma inhibitory
activity 3 [Mus musculus]
         (1930 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

21187                                                                  53   1e-06
02091                                                                  35   0.33 
01750                                                                  31   4.2  
12745                                                                  30   6.6  
>21187
          Length = 1206

 Score = 52.8 bits (125), Expect = 1e-06,   Method: Composition-based stats.
 Identities = 25/74 (33%), Positives = 37/74 (50%)
 Frame = +2

Query: 33  SDLKVCGDEECSMLMYRGKALEDFTGPDCRFVNFKKGDDVYVYYKLAGGSLELWAGSVEH 92
           SDL+ C D+ CS  + +  A+  +      ++   +GD V +  K AG   +LW G V  
Sbjct: 80  SDLRRCADKTCSATLSKATAIGRYPASSPLYLTLNRGDIVEIKSKSAGNRPDLWGGEVNG 259

Query: 93  SFGYFPKDLIKVLH 106
             GYFPK  +K  H
Sbjct: 260 RKGYFPKAFVKEFH 301
>02091
          Length = 2031

 Score = 35.0 bits (79), Expect = 0.33,   Method: Compositional matrix adjust.
 Identities = 34/131 (25%), Positives = 57/131 (43%), Gaps = 4/131 (3%)
 Frame = -1

Query: 906  INSFFKDDQQSLHRFLKYFDVRELEGLLEDMSIRLRSAHQNSLPYNMEKVLDKVFRASES 965
            IN  F D Q SL    +Y     L  L  +    ++   Q ++  N   +   VF ASE 
Sbjct: 1800 INEVFDDLQDSLESQRQYL----LSALQLNKDASIQEXSQAAMIQNATALQKLVFSASEG 1633

Query: 966  RILSMAEKMLDTGVAKNRDLGSKESSP-LEEAEVLDDIQDLIYFVRY---QYSGVETAPL 1021
             ++ M   + +    +  DL S+ SSP + E   +   ++ +Y ++    Q   V+T  +
Sbjct: 1632 SLVHMIRGITE----RVEDLYSQFSSPKMTEGVAMAFDRNQMYRIKADIDQIGNVQTVAM 1465

Query: 1022 VTPPPPEEGWA 1032
             TP  P + WA
Sbjct: 1464 STPAXPGDSWA 1432
>01750
          Length = 1886

 Score = 31.2 bits (69), Expect = 4.2,   Method: Composition-based stats.
 Identities = 19/57 (33%), Positives = 23/57 (40%)
 Frame = +3

Query: 1866 PPGSLGPREFFIPGTRLPPPTHGPQEYPPPPPAVRDSLPSGPREEAKPASPSSVQDR 1922
            P   LG R    P T + PP   P  +P        S  +  R  A PA  +SV DR
Sbjct: 867  PXSCLG*RRLCWPTTCVAPPCRPPCAHPGSSSTASXSTTNCSRPTATPAXSTSVMDR 1037
>12745
          Length = 1532

 Score = 30.4 bits (67), Expect = 6.6,   Method: Composition-based stats.
 Identities = 16/47 (34%), Positives = 21/47 (44%)
 Frame = -3

Query: 67   KKGDDVYVYYKLAGGSLELWAGSVEHSFGYFPKDLIKVLHKYTEEEL 113
            + G+D+YV     GGS E       H    F +DLI    +YT   L
Sbjct: 1500 RSGEDIYVAVTSVGGSSEAA*RRCNHCLALFQQDLISSTLEYTSSRL 1360
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|156231057|ref|NP_766263.2| syntaxin 16 isoform a [Mus
musculus]
         (326 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

30761                                                                  50   1e-06
08305                                                                  45   5e-05
16215                                                                  29   2.7  
15134                                                                  28   5.9  
>30761
          Length = 367

 Score = 50.4 bits (119), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 23/53 (43%), Positives = 33/53 (62%)
 Frame = +1

Query: 248 ISDLNEIFRDLGAMIVEQGTVLDRIDYNVEQSCVKTEDGLKQLHKAEQYQKKN 300
           I  +NEI+++LGAM+ EQG  +D I+  VEQ+ +    G   L KA  Y+ KN
Sbjct: 190 IVGVNEIYKNLGAMVYEQGLTVDSIESQVEQTSIFVSQGTDNLRKASSYRVKN 348
>08305
          Length = 1314

 Score = 44.7 bits (104), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 22/53 (41%), Positives = 35/53 (66%)
 Frame = -3

Query: 247 SISDLNEIFRDLGAMIVEQGTVLDRIDYNVEQSCVKTEDGLKQLHKAEQYQKK 299
           S++D+N +F++L  M+ +QG  LD I+ N+EQ  V  E G +QL +A + Q K
Sbjct: 586 SVTDVNMLFKELNLMVSQQGEKLDSIEQNIEQVEVHVESGKEQLTEAVKSQXK 428
>16215
          Length = 1251

 Score = 28.9 bits (63), Expect = 2.7,   Method: Compositional matrix adjust.
 Identities = 16/40 (40%), Positives = 19/40 (47%), Gaps = 4/40 (10%)
 Frame = +2

Query: 193 ERSQHFF----DTPVPLMDDGDDATLYGQGFTDDQLVLVE 228
           E SQHF       P P +DD     ++GQG  DD L   E
Sbjct: 497 EISQHFGHLVASLPTPHVDDHVAVGVFGQGLRDDSLATAE 616
>15134
          Length = 659

 Score = 27.7 bits (60), Expect = 5.9,   Method: Compositional matrix adjust.
 Identities = 21/56 (37%), Positives = 29/56 (51%), Gaps = 9/56 (16%)
 Frame = +1

Query: 18 IQTRQLLAEQVSSHTTSSPLHSRSIA-------AELD--ELADDRMALVSGISLDP 64
          IQ+ +++  ++ S    SPL SRS A       AEL   E+ D R+  V GI  DP
Sbjct: 34 IQS*RVMLVRIPSPVVKSPLSSRSFATQPQECSAELSRHEIVDKRVDSVVGIQQDP 201
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|159131876|ref|NP_683727.2| FYVE and coiled-coil
domain containing 1 [Mus musculus]
         (1438 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

17699                                                                  52   1e-06
27911                                                                  50   7e-06
05474                                                                  48   3e-05
28053                                                                  46   1e-04
29146                                                                  36   0.097
33803                                                                  35   0.21 
36198                                                                  34   0.42 
15691                                                                  32   2.4  
12557                                                                  31   4.1  
>17699
          Length = 551

 Score = 52.4 bits (124), Expect = 1e-06,   Method: Composition-based stats.
 Identities = 20/38 (52%), Positives = 28/38 (73%)
 Frame = +3

Query: 141 FLKPKLSSDIVGQLYELTEVQFDLAPRGYDLDAAWPTF 178
           +++  LSS I+  LY+L  + FDL+PRGYDLD AWP+ 
Sbjct: 3   WMRQDLSSSIINTLYDLNSLHFDLSPRGYDLDNAWPSL 116
>27911
          Length = 376

 Score = 50.1 bits (118), Expect = 7e-06,   Method: Composition-based stats.
 Identities = 19/42 (45%), Positives = 27/42 (64%)
 Frame = -2

Query: 1135 EVNHCHDCKREFSWIVRRHHCRICGRIFCYYCCNNYVVTKPS 1176
            +V  C++C++ FS   R+HHCR CGRIFC  C    V + P+
Sbjct: 126  DVEDCNNCRQAFSVTKRKHHCRHCGRIFCADCTTKSVNSGPA 1
>05474
          Length = 1214

 Score = 47.8 bits (112), Expect = 3e-05,   Method: Composition-based stats.
 Identities = 23/72 (31%), Positives = 38/72 (52%), Gaps = 2/72 (2%)
 Frame = +1

Query: 1121 QQKLSAEEKCLGDMEVNHCHDCKR-EFSWIVRRHHCRICGRIFCYYCCNN-YVVTKPSGK 1178
            Q++L      + D +   C  CK+ EF+ I RRHHCR CG + C  C +  +++ + S +
Sbjct: 322  QKQLEDSPVWVPDSDTKTCMHCKKSEFTLINRRHHCRHCGIVACNACSSKRWLLPQQSSR 501

Query: 1179 KERCCRACFQKF 1190
              R C  C+ + 
Sbjct: 502  PLRVCLTCYHRL 537
>28053
          Length = 441

 Score = 45.8 bits (107), Expect = 1e-04,   Method: Composition-based stats.
 Identities = 18/34 (52%), Positives = 21/34 (61%)
 Frame = -2

Query: 1133 DMEVNHCHDCKREFSWIVRRHHCRICGRIFCYYC 1166
            D EV  C  C + F  +VRRHHCR+CG I C  C
Sbjct: 329  DKEVPACLTCIKSFGLLVRRHHCRLCGGIMCNKC 228
>29146
          Length = 327

 Score = 36.2 bits (82), Expect = 0.097,   Method: Composition-based stats.
 Identities = 15/41 (36%), Positives = 20/41 (48%)
 Frame = +3

Query: 1132 GDMEVNHCHDCKREFSWIVRRHHCRICGRIFCYYCCNNYVV 1172
            G  +V     C+ +F    R+HHCR CG+ FC  C     V
Sbjct: 102  GSCKVCQNVQCQAKFDLFNRKHHCRRCGKCFCNKCTTGQAV 224
>33803
          Length = 510

 Score = 35.0 bits (79), Expect = 0.21,   Method: Composition-based stats.
 Identities = 15/37 (40%), Positives = 20/37 (54%)
 Frame = +2

Query: 1133 DMEVNHCHDCKREFSWIVRRHHCRICGRIFCYYCCNN 1169
            D  +N C  C+ EF+     HHCR CG+  C+ C  N
Sbjct: 266  DEAINECIVCQLEFNPKRPIHHCRACGQGVCHDCSPN 376
>36198
          Length = 390

 Score = 34.3 bits (77), Expect = 0.42,   Method: Composition-based stats.
 Identities = 14/30 (46%), Positives = 21/30 (70%)
 Frame = +2

Query: 1395 QLKVRIPGIYLLIFDNTFSRFISKKVLYHL 1424
            +L  +  G+Y L+FDN++SR  SKK+ Y L
Sbjct: 56   ELTAKQAGVYTLLFDNSYSRMTSKKISYTL 145
>15691
          Length = 587

 Score = 31.6 bits (70), Expect = 2.4,   Method: Compositional matrix adjust.
 Identities = 22/57 (38%), Positives = 31/57 (54%), Gaps = 2/57 (3%)
 Frame = +3

Query: 839 VRCSSEGAH--LEHAELQDQLHRANTDTAELGIQVCALTAEKDRMEEALASLAQELQ 893
           VR + E  H   E   L+DQL    +  AEL  Q+ ++ AE+D M   L+ L QEL+
Sbjct: 306 VRDNMEAQHAKTEIKRLRDQLAERQSRIAELEAQLASMKAERDNMSMQLSELQQELE 476
>12557
          Length = 1078

 Score = 30.8 bits (68), Expect = 4.1,   Method: Compositional matrix adjust.
 Identities = 16/55 (29%), Positives = 33/55 (60%)
 Frame = +3

Query: 967  SAEIMDHQNRLKTANEECGHLRAQLEEQGQQLQMTKEAVQELEITKAAMEEKLNC 1021
            +A++ + +  LKT+ E+C   +A L++  +Q Q  K  + +L+  K ++  +LNC
Sbjct: 507  TAQLEEMKAELKTSTEDCQQTKASLQQSTEQCQTLKVQLSDLQTHKDSLTSELNC 671
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|30794218|ref|NP_112454.1| WD repeat domain 10 [Mus
musculus]
         (1183 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

27465                                                                  52   1e-06
12574                                                                  49   1e-05
13278                                                                  48   2e-05
00561                                                                  48   2e-05
15780                                                                  48   2e-05
01249                                                                  46   1e-04
19949                                                                  45   2e-04
02147                                                                  43   6e-04
18981                                                                  42   0.001
12806                                                                  42   0.002
30256                                                                  40   0.005
30176                                                                  40   0.007
13335                                                                  39   0.016
17602                                                                  38   0.024
17598                                                                  37   0.054
31474                                                                  35   0.15 
02960                                                                  35   0.16 
33180                                                                  35   0.19 
19140                                                                  35   0.22 
04358                                                                  34   0.31 
15337                                                                  34   0.32 
30297                                                                  34   0.44 
26107                                                                  34   0.45 
19498                                                                  33   0.77 
29912                                                                  33   0.98 
14500                                                                  32   1.1  
14555                                                                  32   1.6  
21105                                                                  32   1.8  
03395                                                                  32   1.9  
01768                                                                  32   2.2  
19863                                                                  30   4.0  
30295                                                                  30   4.1  
15118                                                                  30   5.5  
20662                                                                  29   9.7  
>27465
          Length = 658

 Score = 52.4 bits (124), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 34/115 (29%), Positives = 60/115 (52%), Gaps = 6/115 (5%)
 Frame = -1

Query: 15  IYDLGFKPDGTQLILAAGNRLL-VYDTSDGTLLQPLKGHKDTVYCVAYAKD-GKRFASGS 72
           + ++ F   G+  I  + +R   ++DT+    L  L+GH++ VY +A+    G +  +GS
Sbjct: 352 LTNVAFNKSGSSFITGSYDRTCKIWDTASAEELHTLEGHRNVVYAIAFNNPFGDKVITGS 173

Query: 73  ADKSIIIWTSKLEGILKYT---HNDSIQCVSYNPVTHQLASCS-SSDFGLWSPEQ 123
            DK+  +W S  +G   +T   H   I CVS+NP +  +A+ S  +   LW  E+
Sbjct: 172 FDKTCKLW-STADGKCYHTLRGHTAEIVCVSFNPSSTLIATGSMDTTCRLWDVEK 11
>12574
          Length = 521

 Score = 49.3 bits (116), Expect = 1e-05,   Method: Composition-based stats.
 Identities = 30/97 (30%), Positives = 53/97 (54%), Gaps = 4/97 (4%)
 Frame = +3

Query: 20  FKPDGTQLILAAGNRLL-VYDTSDGTLLQPLKGHKDTVYCVAYAKDGKRFASGSADKSII 78
           F P+G  L  ++ ++L+ ++   DG   + + GHK  +  VA++ D K   S S DK++ 
Sbjct: 210 FSPNGDWLASSSADKLIKIWGAYDGKFEKTIAGHKLGLSDVAWSSDSKLLCSASDDKTLK 389

Query: 79  IW---TSKLEGILKYTHNDSIQCVSYNPVTHQLASCS 112
           IW   T K    LK  H++ + C ++NP ++ + S S
Sbjct: 390 IWEFSTGKCMKTLK-GHSNYVFCCNFNPQSNLIVSGS 497

 Score = 32.0 bits (71), Expect = 1.7,   Method: Composition-based stats.
 Identities = 25/75 (33%), Positives = 38/75 (50%), Gaps = 3/75 (4%)
 Frame = +3

Query: 44  TLLQPLKGHKDTVYCVAYAKDGKRFASGSADKSIIIWTSKLEGILKYT---HNDSIQCVS 100
           TL   L GH   +  V ++ +G   AS SADK I IW +  +G  + T   H   +  V+
Sbjct: 159 TLKFTLAGHTKALSAVKFSPNGDWLASSSADKLIKIWGA-YDGKFEKTIAGHKLGLSDVA 335

Query: 101 YNPVTHQLASCSSSD 115
           ++  +  L  CS+SD
Sbjct: 336 WSSDSKLL--CSASD 374
>13278
          Length = 870

 Score = 48.1 bits (113), Expect = 2e-05,   Method: Composition-based stats.
 Identities = 28/76 (36%), Positives = 41/76 (53%), Gaps = 10/76 (13%)
 Frame = +1

Query: 15  IYDLGFKPDG-------TQLILAAGN---RLLVYDTSDGTLLQPLKGHKDTVYCVAYAKD 64
           IY + + P G       T LILA+ +    + +++   G  L  L  H++ VY VA++ D
Sbjct: 58  IYTIKWSPTGPGTSNPNTSLILASASFDSTVRLWEVERGLCLHTLTKHQEPVYSVAFSPD 237

Query: 65  GKRFASGSADKSIIIW 80
           GK  ASGS DK + IW
Sbjct: 238 GKYLASGSFDKCVHIW 285
>00561
          Length = 1003

 Score = 48.1 bits (113), Expect = 2e-05,   Method: Composition-based stats.
 Identities = 28/95 (29%), Positives = 49/95 (51%), Gaps = 6/95 (6%)
 Frame = -3

Query: 15  IYDLGFKPDGTQLILAAGNRLL-VYDTSDGTLLQPLKGHKDTVYCVAYAKDGKRFASGSA 73
           I D+    DG   +  + ++ L ++D + G   +  +GH   V  VA++ D ++  SGS 
Sbjct: 857 ISDVVLSSDGNYALSGSWDQTLRLWDLAAGKTTRRFEGHTKDVLSVAFSADNRQIVSGSR 678

Query: 74  DKSIIIWTSKLEGILKYT-----HNDSIQCVSYNP 103
           DK+I +W +  E   K+T     H D + CV ++P
Sbjct: 677 DKTIKLWNTLAE--CKFTIQEDGHTDWVSCVRFSP 579

 Score = 30.4 bits (67), Expect(2) = 0.72,   Method: Composition-based stats.
 Identities = 21/85 (24%), Positives = 35/85 (41%), Gaps = 2/85 (2%)
 Frame = -3

Query: 37  VYDTSDGTLLQPLKGHKDTVYCVAYAKDGKRFASGSADKSIIIWTSKLEGILKYT--HND 94
           V++ ++  L     GH   +  V  + DG    SG  D   ++W    +G   YT  HND
Sbjct: 527 VWNLANCKLKNNHHGHNGYLNTVTVSPDGSLCTSGGKDSKALLWDLN-DGKNLYTLEHND 351

Query: 95  SIQCVSYNPVTHQLASCSSSDFGLW 119
            I  + ++P  + L         +W
Sbjct: 350 IINALCFSPNRYWLCVAYGPSIKIW 276

 Score = 21.2 bits (43), Expect(2) = 0.72,   Method: Composition-based stats.
 Identities = 7/20 (35%), Positives = 12/20 (60%)
 Frame = -2

Query: 139 SWTNDGQYLALGMANGIISI 158
           +W+ DGQ L  G ++  I +
Sbjct: 186 AWSTDGQTLFAGYSDNTIRV 127

 Score = 30.4 bits (67), Expect = 4.6,   Method: Composition-based stats.
 Identities = 24/90 (26%), Positives = 39/90 (43%), Gaps = 8/90 (8%)
 Frame = -3

Query: 39  DTSDGTLLQPLKGHKDTVYCVAYAKDGKRFASGSADKSIIIW-------TSKLEGILKYT 91
           DT+ G   + L GH   +  V  + DG    SGS D+++ +W       T + EG     
Sbjct: 908 DTNYGYPQKRLYGHSHFISDVVLSSDGNYALSGSWDQTLRLWDLAAGKTTRRFEG----- 744

Query: 92  HNDSIQCVSYNPVTHQLASCS-SSDFGLWS 120
           H   +  V+++    Q+ S S      LW+
Sbjct: 743 HTKDVLSVAFSADNRQIVSGSRDKTIKLWN 654
>15780
          Length = 735

 Score = 48.1 bits (113), Expect = 2e-05,   Method: Composition-based stats.
 Identities = 20/51 (39%), Positives = 31/51 (60%)
 Frame = -1

Query: 30  AAGNRLLVYDTSDGTLLQPLKGHKDTVYCVAYAKDGKRFASGSADKSIIIW 80
            A + ++V+D + GT +  L  H DTVY + +++DG   ASG  D SI +W
Sbjct: 717 GADHTVIVWDIASGTAVAHLTAHTDTVYALCFSRDGTVLASGGMDNSIRLW 565
>01249
          Length = 1743

 Score = 45.8 bits (107), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 17/32 (53%), Positives = 24/32 (75%)
 Frame = -1

Query: 49  LKGHKDTVYCVAYAKDGKRFASGSADKSIIIW 80
           L+GH D V C+A++ DG+R ASGS +  +IIW
Sbjct: 927 LQGHSDAVTCLAFSSDGQRLASGSQNGKVIIW 832

 Score = 30.0 bits (66), Expect = 5.0,   Method: Compositional matrix adjust.
 Identities = 26/90 (28%), Positives = 43/90 (47%), Gaps = 3/90 (3%)
 Frame = -1

Query: 135 ITCCSWTNDGQYLALGMANGIISIRNKNGEEKVKIERPG--GSLSPIWSICWNPSREEHN 192
           +TC ++++DGQ LA G  NG + I N    +   ++  G  G++  I  I  + +     
Sbjct: 906 VTCLAFSSDGQRLASGSQNGKVIIWNMESGDSTSLDISGAVGNVMIIPPIVHSSTX---- 739

Query: 193 DILAVADWGQKLSFYQ-LSGKQIGKDRPLN 221
                A  G  +SF Q +S ++ GK R  N
Sbjct: 738 -----AHQGPPISFKQHISREEDGKGRVFN 664
>19949
          Length = 903

 Score = 45.1 bits (105), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 28/93 (30%), Positives = 50/93 (53%), Gaps = 3/93 (3%)
 Frame = +2

Query: 14  CIYDLGFKPDGTQLILAAGNRLL-VYDTSDGTLLQPLKGHKDTVYCVAYAKDGKRFASGS 72
           C+  L F PDG  +  A+ + L+ ++D + G LL  LK H+D V  + +       ASGS
Sbjct: 125 CVCCLRFSPDGRWIASASEDGLVKLWDLTAGKLLTDLKLHRDAVNTIEFHPHEFLLASGS 304

Query: 73  ADKSIIIWTSKLEGILKYT--HNDSIQCVSYNP 103
           AD+++  W  +   ++  T    +SI+ + ++P
Sbjct: 305 ADRTVKFWDLETFQLISTTEPEANSIRSILFHP 403

 Score = 37.4 bits (85), Expect = 0.039,   Method: Compositional matrix adjust.
 Identities = 30/105 (28%), Positives = 49/105 (46%), Gaps = 6/105 (5%)
 Frame = +2

Query: 15  IYDLGFKPDGTQLILAAGN---RLLVYDTSDGTLLQPLKGHKDTVYCVAYAKDGKRFASG 71
           +  L F P G     A+G+    + ++D      +   KGH   V C+ ++ DG+  AS 
Sbjct: 2   VKSLDFHPYGA--YTASGSMDCNVKLWDIRRKGCIYTYKGHTGCVCCLRFSPDGRWIASA 175

Query: 72  SADKSIIIW---TSKLEGILKYTHNDSIQCVSYNPVTHQLASCSS 113
           S D  + +W     KL   LK  H D++  + ++P    LAS S+
Sbjct: 176 SEDGLVKLWDLTAGKLLTDLKL-HRDAVNTIEFHPHEFLLASGSA 307
>02147
          Length = 1547

 Score = 43.1 bits (100), Expect = 6e-04,   Method: Compositional matrix adjust.
 Identities = 60/285 (21%), Positives = 115/285 (40%), Gaps = 14/285 (4%)
 Frame = +2

Query: 43  GTLLQPLKGHKDTVYCVAYAKDGKRFASGSADKSIIIWTS-KLEGILKYTHNDSIQCVSY 101
           G  +   +GHK  V+     ++  R A+G+AD S  IW + K E +  ++H   ++ V +
Sbjct: 143 GDWIGTFEGHKGAVWGATLNREATRAATGAADFSAKIWDAEKGEELQTFSHKHIVKSVDF 322

Query: 102 NPVTHQLASCSSSD----FGLWSPEQXXXXXXXXXXXITCCSWTNDGQYLALGMANGIIS 157
           +     L + S+      F L + +            I    + +DG+ +    A+   +
Sbjct: 323 SHDGTALLTGSNEKLLKVFDLVNTDAEPKSFAGHTSNIKGALFLSDGKRII--SASDDKT 496

Query: 158 IRNKNGEEKVKIERPGGSLSPIWSICWNPSREEHNDILAVADWGQKLSFYQLSG----KQ 213
           +R  + E   ++++      P  S+  +P +   N I+      Q ++FYQ       K+
Sbjct: 497 VRLWSLETCQEVQQLTFDTPPT-SLTLSPDK---NTIIVTHS--QNIAFYQADTLREMKK 658

Query: 214 IGKDRPLNFDPCCISYFTKGEYILVGGSDKQVSLFT-KDGVRLGTVGEQNSWVWTCRVKP 272
              + P++      S      + + GG D ++  F  + G  + +       V   R  P
Sbjct: 659 FEAEAPIS----SASLHQSERFFVAGGEDFKMYKFDYETGKEIESFKGHFGPVHCVRFSP 826

Query: 273 DSNYVVVGCQDGTISFYQLIFSTVHGLYK----DRYAYRDSMTDV 313
           D      G +DGT+  +Q      +GL+K    D    ++S  DV
Sbjct: 827 DGELYASGSEDGTLRLWQTTIGRTYGLWKCVIPDEADAQNSTPDV 961

 Score = 41.6 bits (96), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 19/61 (31%), Positives = 34/61 (55%), Gaps = 2/61 (3%)
 Frame = +2

Query: 26  QLILAAGNRLLVY--DTSDGTLLQPLKGHKDTVYCVAYAKDGKRFASGSADKSIIIWTSK 83
           +  +A G    +Y  D   G  ++  KGH   V+CV ++ DG+ +ASGS D ++ +W + 
Sbjct: 707 RFFVAGGEDFKMYKFDYETGKEIESFKGHFGPVHCVRFSPDGELYASGSEDGTLRLWQTT 886

Query: 84  L 84
           +
Sbjct: 887 I 889

 Score = 37.7 bits (86), Expect = 0.025,   Method: Compositional matrix adjust.
 Identities = 22/73 (30%), Positives = 37/73 (50%), Gaps = 3/73 (4%)
 Frame = +2

Query: 12  EQCIYDLGFKPDGTQLILAAGNRLL-VYDTSDGTLLQP--LKGHKDTVYCVAYAKDGKRF 68
           +  +  + F  DGT L+  +  +LL V+D  + T  +P    GH   +    +  DGKR 
Sbjct: 296 KHIVKSVDFSHDGTALLTGSNEKLLKVFDLVN-TDAEPKSFAGHTSNIKGALFLSDGKRI 472

Query: 69  ASGSADKSIIIWT 81
            S S DK++ +W+
Sbjct: 473 ISASDDKTVRLWS 511
>18981
          Length = 407

 Score = 42.4 bits (98), Expect = 0.001,   Method: Composition-based stats.
 Identities = 24/55 (43%), Positives = 33/55 (60%), Gaps = 1/55 (1%)
 Frame = -2

Query: 27  LILAAGNRLL-VYDTSDGTLLQPLKGHKDTVYCVAYAKDGKRFASGSADKSIIIW 80
           +I AA +R L V+   +  LL  L+GH D V CV     G+R  SGS DK++I+W
Sbjct: 379 IISAATDRTLRVWCLKNTCLLHTLRGHNDDVECVCIY--GRRVVSGSWDKTLIVW 221
>12806
          Length = 961

 Score = 41.6 bits (96), Expect = 0.002,   Method: Composition-based stats.
 Identities = 26/86 (30%), Positives = 41/86 (47%), Gaps = 5/86 (5%)
 Frame = +3

Query: 35  LLVYDTSDGTLLQPLKGHKDTVYCVAYAKDGKRFASGSADKSIIIWTSKLEGILKYT--- 91
           L ++D   G+       H   V  VA++ D ++ ASG  DK++ IW   + G  KYT   
Sbjct: 237 LRLWDIKKGSTTSRFINHTRDVLTVAFSPDNRQIASGGRDKNLKIWN--IMGECKYTVDA 410

Query: 92  --HNDSIQCVSYNPVTHQLASCSSSD 115
             H D + CV ++  T      S+S+
Sbjct: 411 NAHTDWVTCVRFHQDTKNPIVVSASN 488
>30256
          Length = 961

 Score = 40.4 bits (93), Expect = 0.005,   Method: Composition-based stats.
 Identities = 22/55 (40%), Positives = 30/55 (54%), Gaps = 3/55 (5%)
 Frame = +3

Query: 29  LAAGNR---LLVYDTSDGTLLQPLKGHKDTVYCVAYAKDGKRFASGSADKSIIIW 80
           + +G+R   L V+D   G  L  L GH   V CV Y  DGKR  SG+ D ++ +W
Sbjct: 201 VVSGSRDATLRVWDIESGHCLNVLLGHMAAVRCVQY--DGKRVVSGAXDYTVRVW 359

 Score = 38.5 bits (88), Expect = 0.017,   Method: Composition-based stats.
 Identities = 24/82 (29%), Positives = 41/82 (50%), Gaps = 3/82 (3%)
 Frame = +3

Query: 24  GTQLILAAGNRLL-VYDTSDGTLLQPLKGHKDTVYCVAYAKDGKRFASGSADKSIIIWTS 82
           G  +I  + +R L V++   G     L GH  TV C++ +  GK+  SGS D ++ +W  
Sbjct: 72  GNTVISGSTDRSLKVWNADTGVCTHTLYGHSSTVRCLSLS--GKKVVSGSRDATLRVWDI 245

Query: 83  KLEGILKYT--HNDSIQCVSYN 102
           +    L     H  +++CV Y+
Sbjct: 246 ESGHCLNVLLGHMAAVRCVQYD 311

 Score = 36.6 bits (83), Expect = 0.066,   Method: Composition-based stats.
 Identities = 20/59 (33%), Positives = 32/59 (54%), Gaps = 1/59 (1%)
 Frame = +3

Query: 23  DGTQLILAAGNRLL-VYDTSDGTLLQPLKGHKDTVYCVAYAKDGKRFASGSADKSIIIW 80
           DG +++  A +  + V+D    + L  L+GH + VY + +  DG    SGS D SI +W
Sbjct: 309 DGKRVVSGAXDYTVRVWDPDTASCLHTLQGHTNRVYSLQF--DGVYVVSGSLDTSIRVW 479
>30176
          Length = 365

 Score = 39.7 bits (91), Expect = 0.007,   Method: Composition-based stats.
 Identities = 22/55 (40%), Positives = 30/55 (54%), Gaps = 4/55 (7%)
 Frame = +2

Query: 49 LKGHKDTVYCVAYAKDGKRFASGSADKSIIIWTSKL----EGILKYTHNDSIQCV 99
          LK H  TV+ + + K G R AS S DK+I IW   L    EGI+   +  + +CV
Sbjct: 8  LKSHTSTVWNLTFDKTGTRLASCSDDKTIKIWQEYLPGNPEGIVTKDNEPTWKCV 172
>13335
          Length = 863

 Score = 38.5 bits (88), Expect = 0.016,   Method: Compositional matrix adjust.
 Identities = 19/91 (20%), Positives = 43/91 (47%), Gaps = 6/91 (6%)
 Frame = +1

Query: 20  FKPDGTQLILAAGN-RLLVYDTSDGTLLQPLKGHKDTVYCVAYAKDGKRFASGSADKSII 78
           F P  + L+  + +  + +++ +   L++   GH+D+V  +AY+ +G    SGS +  + 
Sbjct: 85  FSPSSSHLVSGSDDDTICMWEVATQKLVRSYVGHEDSVMALAYSPNGHYLVSGSPNGDLY 264

Query: 79  IWTSKLEGILKYT-----HNDSIQCVSYNPV 104
           +W +        T     H+  + C  ++P 
Sbjct: 265 VWDASFGHCRHLTLRVDAHDLGVTCCEFSPT 357

 Score = 36.6 bits (83), Expect = 0.065,   Method: Compositional matrix adjust.
 Identities = 27/83 (32%), Positives = 42/83 (50%), Gaps = 8/83 (9%)
 Frame = +1

Query: 19  GFKPDGTQLILAAGN---RLLVYDTSDGTLLQPLKG-HKDTVYCVAYAKDGKRFASGSAD 74
            F P  +  +LA+G+    + ++D+  G  L  ++  H   V C A++ DG   ASGS D
Sbjct: 529 AFSP--SSALLASGSFDKSVRLWDSVKGVALFSIEACHSRFVTCCAFSIDGTLLASGSMD 702

Query: 75  KSIIIW----TSKLEGILKYTHN 93
           + I IW    TS + G L   +N
Sbjct: 703 RIIKIWKLTDTSSIMGKLSLFYN 771

 Score = 35.4 bits (80), Expect = 0.16,   Method: Compositional matrix adjust.
 Identities = 29/110 (26%), Positives = 45/110 (40%)
 Frame = +1

Query: 49  LKGHKDTVYCVAYAKDGKRFASGSADKSIIIWTSKLEGILKYTHNDSIQCVSYNPVTHQL 108
           L GH D V   A++      ASGS DKS+ +W S ++G+  ++                +
Sbjct: 496 LSGHSDLVMACAFSPSSALLASGSFDKSVRLWDS-VKGVALFS----------------I 624

Query: 109 ASCSSSDFGLWSPEQXXXXXXXXXXXITCCSWTNDGQYLALGMANGIISI 158
            +C S                     +TCC+++ DG  LA G  + II I
Sbjct: 625 EACHS-------------------RFVTCCAFSIDGTLLASGSMDRIIKI 717
>17602
          Length = 481

 Score = 38.1 bits (87), Expect = 0.024,   Method: Compositional matrix adjust.
 Identities = 29/90 (32%), Positives = 40/90 (44%), Gaps = 16/90 (17%)
 Frame = +3

Query: 7   WRDKAEQCIYDL-----------GFKPDGTQLILAA--GNRLLVYDTSDGTLLQPLKGHK 53
           W   + QC+  L            F P+G + ILAA   N L ++D S G  L+   GH+
Sbjct: 135 WDTASGQCLXTLIDDDNPPVSFVKFSPNG-KYILAATLDNTLKLWDYSKGKCLKTYVGHR 311

Query: 54  DTVYCV---AYAKDGKRFASGSADKSIIIW 80
           +  YC+        GK   SGS D  + IW
Sbjct: 312 NEKYCIFANFSVTGGKWIVSGSEDNMVYIW 401

 Score = 30.8 bits (68), Expect = 3.5,   Method: Compositional matrix adjust.
 Identities = 15/44 (34%), Positives = 20/44 (45%)
 Frame = +3

Query: 37 VYDTSDGTLLQPLKGHKDTVYCVAYAKDGKRFASGSADKSIIIW 80
          ++D   G  L+ L  H D V  V + +DG    S S D    IW
Sbjct: 6  IWDVKTGKCLKTLPAHSDPVTAVHFNRDGSLIVSSSYDGLCRIW 137
>17598
          Length = 875

 Score = 36.6 bits (83), Expect = 0.054,   Method: Compositional matrix adjust.
 Identities = 21/73 (28%), Positives = 35/73 (47%), Gaps = 5/73 (6%)
 Frame = +1

Query: 35  LLVYDTSDGTLLQPLKGHKDTVYCVAYAKDGKRFASGSADKSIIIWTSKLEGILKYT--- 91
           L ++D   G   +    H      VA++ D ++ ASG  DK++ IW +   G  K+T   
Sbjct: 193 LRLWDIKKGNTTRRFISHTRDALAVAFSPDNRQIASGGRDKALKIWNT--VGECKFTVDA 366

Query: 92  --HNDSIQCVSYN 102
             H D + CV ++
Sbjct: 367 NSHQDWVTCVKFH 405

 Score = 29.3 bits (64), Expect = 9.6,   Method: Compositional matrix adjust.
 Identities = 23/89 (25%), Positives = 35/89 (39%), Gaps = 2/89 (2%)
 Frame = +1

Query: 37  VYDTSDGTLLQPLKGHKDTVYCVAYAKDGKRFASGSADKSIIIWTSKLEGILKYTHND-S 95
           V+D    TL     GHK  +  +  A      ASGS D  ++ W  +    L     D  
Sbjct: 460 VWDNQTMTLKHTFVGHKTQINAIDLALKTYYLASGSKDGIVMTWNIQNGTFLGKIDCDCE 639

Query: 96  IQCVSYNPVTHQLASCSSSDFGLWS-PEQ 123
           +  V ++P  + L   +S    +W  P Q
Sbjct: 640 VNAVKFSPNKYWLFVGTSEGIQIWDLPNQ 726
>31474
          Length = 403

 Score = 35.4 bits (80), Expect = 0.15,   Method: Composition-based stats.
 Identities = 21/78 (26%), Positives = 37/78 (47%), Gaps = 6/78 (7%)
 Frame = -3

Query: 49  LKGHKDTVYCVAYAKDGKRFASGSADKSIIIWTSK-----LEGILKYTHNDSIQCVSYNP 103
           L  H +  +CVA+   G   AS  +DK I IW  +      +  L   H  +++ + ++P
Sbjct: 317 LSAHDEHAWCVAWNPTGTLLASCGSDKIIKIWGKEGDNWVCKSTLTDAHTRTVRSLGWSP 138

Query: 104 VTHQLASCS-SSDFGLWS 120
             + L+S S  +   +WS
Sbjct: 137 CGNYLSSASFDATTAVWS 84
>02960
          Length = 1577

 Score = 35.0 bits (79), Expect = 0.16,   Method: Compositional matrix adjust.
 Identities = 29/111 (26%), Positives = 53/111 (47%), Gaps = 12/111 (10%)
 Frame = +2

Query: 24  GTQLILAAGNRLLVYDTSDGTLLQPLKGHKDTVYCVAYAKDGKR-----FASGSADKSII 78
           G  L  +  N + ++ T  G  +  + GH   V CVA+ K  +      F +GS D++ +
Sbjct: 518 GXXLSGSYDNTVRLWSTK-GEAIMTIPGHTSPVKCVAWIKHDESSGVSTFVTGSHDQTAL 694

Query: 79  IW-----TSKLEGILK-YTHNDSIQCVSYNPVTHQLASCSSSD-FGLWSPE 122
           +W     T++++  L    H  S+ CV+ +P + Q+ + S      LWS +
Sbjct: 695 VWQWQRETNEVDCRLSCRGHAASVDCVAVSPDSQQMCTGSWDKMLKLWSTD 847
>33180
          Length = 460

 Score = 35.0 bits (79), Expect = 0.19,   Method: Compositional matrix adjust.
 Identities = 22/72 (30%), Positives = 32/72 (44%), Gaps = 2/72 (2%)
 Frame = -2

Query: 14  CIYDLGFKPDGTQLILAAGNRLL-VYDTSDGTLLQPLKGHKDTVYCVAYAKDGKRFA-SG 71
           CI+ L F  D T+++  A +  L VYD         +  H D V  VA+A D  +   SG
Sbjct: 447 CIFSLMFSSDNTEIVGGANDGCLYVYDRESNQRTLKIDAHDDDVNAVAFADDSSQILYSG 268

Query: 72  SADKSIIIWTSK 83
             D    +W  +
Sbjct: 267 GDDGLCKVWDRR 232
>19140
          Length = 573

 Score = 34.7 bits (78), Expect = 0.22,   Method: Compositional matrix adjust.
 Identities = 15/36 (41%), Positives = 22/36 (61%)
 Frame = -3

Query: 46  LQPLKGHKDTVYCVAYAKDGKRFASGSADKSIIIWT 81
           L  LKGH D V  +   +DG +  SGS+D +I +W+
Sbjct: 508 LMKLKGHTDNVKALVLNRDGTQCLSGSSDGTIRLWS 401
>04358
          Length = 2430

 Score = 34.3 bits (77), Expect = 0.31,   Method: Compositional matrix adjust.
 Identities = 13/37 (35%), Positives = 20/37 (54%)
 Frame = +1

Query: 51   GHKDTVYCVAYAKDGKRFASGSADKSIIIWTSKLEGI 87
            GH DTV C+ + K  +   +G  D  + +W+S   GI
Sbjct: 2140 GHTDTVRCLHWDKQTQTLVTGGEDSMLCLWSSDASGI 2250
>15337
          Length = 860

 Score = 34.3 bits (77), Expect = 0.32,   Method: Compositional matrix adjust.
 Identities = 21/104 (20%), Positives = 46/104 (44%), Gaps = 3/104 (2%)
 Frame = -1

Query: 15  IYDLGFKPDGTQL-ILAAGNRLLVYDTSDGTLLQPLKGHKDTVYCVAYAKDGKRFASGSA 73
           I +  F P    L ++     L V++ +   L+  +K +   + CV ++ DGK   +G  
Sbjct: 320 ISEFAFSPCSRYLAVVGQDGHLRVFNYNSMELIGTMKSYFGGLLCVCWSPDGKYIVTGGE 141

Query: 74  DKSIIIWTSKLEGIL--KYTHNDSIQCVSYNPVTHQLASCSSSD 115
           D  + +W+   + ++   + H   +  V+++   H   +C   D
Sbjct: 140 DDLVTVWSFHEKRVVCRGHGHKSWVNVVAFD--IHTCLACDDED 15
>30297
          Length = 822

 Score = 33.9 bits (76), Expect = 0.44,   Method: Composition-based stats.
 Identities = 18/69 (26%), Positives = 35/69 (50%)
 Frame = -1

Query: 39  DTSDGTLLQPLKGHKDTVYCVAYAKDGKRFASGSADKSIIIWTSKLEGILKYTHNDSIQC 98
           +T    ++Q  +GH ++V C+   +  K   + +AD ++ +WT+    I  +   +    
Sbjct: 270 ETDSPDVIQSWRGHVESVSCLDLVEQNKVLLTSAADCTVRMWTTDGHYIGTFGQPELWDI 91

Query: 99  VSYNPVTHQ 107
             YNPVT+Q
Sbjct: 90  --YNPVTYQ 70
>26107
          Length = 1338

 Score = 33.9 bits (76), Expect = 0.45,   Method: Compositional matrix adjust.
 Identities = 53/253 (20%), Positives = 101/253 (39%), Gaps = 28/253 (11%)
 Frame = -3

Query: 15   IYDLGFKPDGTQLILAAGNRLL-VYDTSDGTLLQPLKGHKDTVYCVAYAKDGK-RFASGS 72
            ++D  +  + +Q + A+G++ + ++D    T +    GHK +V  VA       + ASG+
Sbjct: 1078 VFDYSWISNDSQCLTASGDQTVALWDVETTTKVTTFIGHKCSVRSVASCPSSPAQCASGA 899

Query: 73   ADKSIIIWTSKLEGILKYTHNDSIQCV------SYNPVTHQLASCSSSDFGLWSPEQXXX 126
             D  I++W S++    ++     +  V         P  H+    ++   G+   +Q   
Sbjct: 898  RDGHIMLWDSRVNKKREHQPCSQVHQVCPQSGHQSKPAKHRRIHRAAGPKGVMDTQQ--- 728

Query: 127  XXXXXXXXITCCSWTNDGQYLALGMANGIISI-------RNKNGEEKVKI---ERPGG-- 174
                    +TC  +  D   ++ G  +G + +        N      V +   + PG   
Sbjct: 727  -------SVTCVLYQTDNLIISSGANDGCVKMWDTRKWYTNTTTSLPVPVHTFDYPGHMR 569

Query: 175  SLSPIWSICWNPSREEHNDILAVADWGQKLSFYQLSGK--------QIGKDRPLNFDPCC 226
             L  I ++C +P + +    L V+    K+  YQL+G+          G      F  C 
Sbjct: 568  RLKGIVTMCMDPWKSQ----LFVSYTDNKVYRYQLAGQYREPQEYVYAGHRNDTFFVRCA 401

Query: 227  ISYFTKGEYILVG 239
            IS    G+Y+L G
Sbjct: 400  IS--PDGKYLLSG 368
>19498
          Length = 903

 Score = 33.1 bits (74), Expect = 0.77,   Method: Compositional matrix adjust.
 Identities = 15/36 (41%), Positives = 22/36 (61%)
 Frame = -1

Query: 45  LLQPLKGHKDTVYCVAYAKDGKRFASGSADKSIIIW 80
           +L  +  H   V CV ++++GK  ASG  DK I+IW
Sbjct: 810 VLCQMDSHLGCVNCVRWSENGKFLASGGDDKLIMIW 703

 Score = 31.6 bits (70), Expect = 1.8,   Method: Compositional matrix adjust.
 Identities = 20/70 (28%), Positives = 35/70 (50%), Gaps = 8/70 (11%)
 Frame = -1

Query: 49  LKGHKDTVYCVAYAKDGKRFASGSADKSIIIWTSKLEGILKYT--------HNDSIQCVS 100
           L+GH   V  +A++      AS S D +I++W +     LK++        H   ++ V+
Sbjct: 621 LRGHAGDVLDLAWSPQDLWLASCSVDNTIVVWNA-----LKFSEQVAVIRGHAGMVKGVT 457

Query: 101 YNPVTHQLAS 110
           ++PV   LAS
Sbjct: 456 WDPVGRYLAS 427
>29912
          Length = 510

 Score = 32.7 bits (73), Expect = 0.98,   Method: Composition-based stats.
 Identities = 13/38 (34%), Positives = 22/38 (57%)
 Frame = +3

Query: 49  LKGHKDTVYCVAYAKDGKRFASGSADKSIIIWTSKLEG 86
           L GH   V  + ++ DGK  ASG+ D  + +W +++ G
Sbjct: 246 LSGHSQEVCGLRWSPDGKYLASGANDNLLCVWPAQVTG 359

 Score = 32.3 bits (72), Expect = 1.1,   Method: Composition-based stats.
 Identities = 15/51 (29%), Positives = 27/51 (52%)
 Frame = +3

Query: 135 ITCCSWTNDGQYLALGMANGIISIRNKNGEEKVKIERPGGSLSPIWSICWN 185
           I   SW  +G YLALG + G + + +   ++K++     G  + + S+ WN
Sbjct: 18  IGAVSWIKEGNYLALGTSTGEVQVWDVTQQKKLRTM--AGHAARVGSLSWN 164
>14500
          Length = 1238

 Score = 32.3 bits (72), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 19/76 (25%), Positives = 35/76 (46%)
 Frame = +3

Query: 5   LTWRDKAEQCIYDLGFKPDGTQLILAAGNRLLVYDTSDGTLLQPLKGHKDTVYCVAYAKD 64
           L W  +  + I   GF          A N+L+++     + +  L GH   V  +A + D
Sbjct: 351 LLWSKEHRELISSHGF----------AQNQLIIWKYPAMSRVAELTGHTARVLHMAMSPD 500

Query: 65  GKRFASGSADKSIIIW 80
           G+   S +AD+++ +W
Sbjct: 501 GETVVSAAADETLRLW 548

 Score = 32.3 bits (72), Expect = 1.1,   Method: Composition-based stats.
 Identities = 13/38 (34%), Positives = 22/38 (57%)
 Frame = +2

Query: 49 LKGHKDTVYCVAYAKDGKRFASGSADKSIIIWTSKLEG 86
          L GH   V  + ++ DGK  ASG+ D  + +W +++ G
Sbjct: 47 LSGHSQEVCGLRWSPDGKYLASGANDNLLCVWPAQVTG 160
>14555
          Length = 627

 Score = 32.0 bits (71), Expect = 1.6,   Method: Composition-based stats.
 Identities = 15/44 (34%), Positives = 22/44 (50%)
 Frame = -3

Query: 37  VYDTSDGTLLQPLKGHKDTVYCVAYAKDGKRFASGSADKSIIIW 80
           V+D   G     L GH + V C+  + DG    +GS D ++ IW
Sbjct: 388 VWDALKGMRSTILYGHDNRVSCLRISPDGTSLCTGSWDYTLRIW 257
>21105
          Length = 650

 Score = 31.6 bits (70), Expect = 1.8,   Method: Compositional matrix adjust.
 Identities = 15/44 (34%), Positives = 23/44 (52%)
 Frame = +1

Query: 38  YDTSDGTLLQPLKGHKDTVYCVAYAKDGKRFASGSADKSIIIWT 81
           +D + G L+  +  H D+V  +A   +G    SGS D SI +W 
Sbjct: 145 FDNNTGKLIHAMVAHLDSVTSLAVDPNGLYLLSGSHDCSIRLWN 276
>03395
          Length = 2795

 Score = 31.6 bits (70), Expect = 1.9,   Method: Compositional matrix adjust.
 Identities = 22/88 (25%), Positives = 39/88 (44%), Gaps = 2/88 (2%)
 Frame = +2

Query: 206 FYQLSGKQIGKDRPLNFDPCCISYFTKGEYILVGGSDKQVSL--FTKDGVRLGTVGEQNS 263
             +L G Q G    ++ D         G+ IL GG D  + L  + +  V    +G  N 
Sbjct: 374 LRELEGSQTGAINTIDIDR-------DGQTILTGGEDSLLKLWRYNEGEVTHTGIGHSNQ 532

Query: 264 WVWTCRVKPDSNYVVVGCQDGTISFYQL 291
            +   R+ P+ +Y+V G +DG +  ++ 
Sbjct: 533 -ITKARICPNRHYIVSGGEDGALHIWKF 613
>01768
          Length = 1424

 Score = 31.6 bits (70), Expect = 2.2,   Method: Compositional matrix adjust.
 Identities = 18/72 (25%), Positives = 35/72 (48%), Gaps = 7/72 (9%)
 Frame = +3

Query: 51  GHKDTVYCVAYA-KDGKRFASGSADKSIIIWTSKLEG------ILKYTHNDSIQCVSYNP 103
            H D+V  V ++  +G  FAS S D+++ IW ++ +        +   H+  I  +++NP
Sbjct: 831 AHTDSVEDVQWSPNEGNVFASCSVDRTLRIWNTQQKPSKANVLTVPEAHSRDINVINWNP 1010

Query: 104 VTHQLASCSSSD 115
           +   L +    D
Sbjct: 1011IEKHLLASGGDD 1046
>19863
          Length = 502

 Score = 30.4 bits (67), Expect = 4.0,   Method: Composition-based stats.
 Identities = 18/59 (30%), Positives = 31/59 (52%), Gaps = 1/59 (1%)
 Frame = +1

Query: 23 DGTQLILAAGN-RLLVYDTSDGTLLQPLKGHKDTVYCVAYAKDGKRFASGSADKSIIIW 80
          DG QL+  + +  ++V+D  +G     L+GH   V  V +++D     S S D ++ IW
Sbjct: 4  DGLQLVSGSSDMSIVVWDVENGVQKLRLQGHAGWVNDVHFSQDQCWLLSCSNDNTVRIW 180
>30295
          Length = 593

 Score = 30.4 bits (67), Expect = 4.1,   Method: Composition-based stats.
 Identities = 13/31 (41%), Positives = 15/31 (48%)
 Frame = +2

Query: 261 QNSWVWTCRVKPDSNYVVVGCQDGTISFYQL 291
           ++SWV TC   P   YV  G  D   S Y L
Sbjct: 368 RSSWVMTCAYAPSGGYVACGGLDNICSIYSL 460
>15118
          Length = 1074

 Score = 30.0 bits (66), Expect = 5.5,   Method: Composition-based stats.
 Identities = 22/119 (18%), Positives = 47/119 (39%), Gaps = 10/119 (8%)
 Frame = +3

Query: 8   RDKAEQCIYDLGFKPDGTQLILAAGNRLL----------VYDTSDGTLLQPLKGHKDTVY 57
           RD+A   + +L      ++++L   + +L          V D     +++   GH +++ 
Sbjct: 288 RDRARVLLKELKMSEGISRILLHRDSNMLAVVLEDFTVSVIDVDTLRVVRVFSGHSNSIT 467

Query: 58  CVAYAKDGKRFASGSADKSIIIWTSKLEGILKYTHNDSIQCVSYNPVTHQLASCSSSDF 116
            ++++ DG+   + S D ++  W+          H   I C +       L    S DF
Sbjct: 468 DLSFSGDGRWLITASMDCTVRTWS--------LVHGRLIDCFAVEAAVTSLTMSPSQDF 620
>20662
          Length = 1220

 Score = 29.3 bits (64), Expect = 9.7,   Method: Compositional matrix adjust.
 Identities = 29/117 (24%), Positives = 45/117 (38%), Gaps = 8/117 (6%)
 Frame = +2

Query: 52  HKDTVYCVAYAKDGKRFASGSADKSIIIWTSKLEGILKY-THNDSIQCVSYNPVTHQL-A 109
           H D    V+   D   + S S D  I +W + L  +  Y  H+D +  V  +P    L  
Sbjct: 383 HDDMTASVSINSDXSHYLSASYDHGIKVWNTDLTSLYTYRAHSDIVWDVQCHPTEPALFL 562

Query: 110 SCS-SSDFGLW----SPEQXXXXXXXXXXXITCCSWTNDGQYL-ALGMANGIISIRN 160
           SCS      LW    S               TC  W  + + + A+G   G +S+++
Sbjct: 563 SCSQDGKIVLWDVRESKPATCLPKCSSGFKPTCVQWQPNARNMYAVGDEGGHVSVQD 733
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31559891|ref|NP_067511.4| mitochondrial Rho 1 [Mus
musculus]
         (631 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

11728                                                                  52   1e-06
19006                                                                  49   4e-06
26083                                                                  41   0.001
34468                                                                  41   0.001
30760                                                                  37   0.024
17511                                                                  34   0.17 
10708                                                                  33   0.25 
09827                                                                  32   0.62 
17872                                                                  32   0.81 
08153                                                                  32   1.0  
12605                                                                  31   1.2  
17337                                                                  31   1.8  
13901                                                                  30   2.2  
18208                                                                  30   3.9  
28329                                                                  30   4.1  
04057                                                                  28   7.9  
>11728
          Length = 635

 Score = 51.6 bits (122), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 35/122 (28%), Positives = 62/122 (50%), Gaps = 2/122 (1%)
 Frame = -1

Query: 18  VRILLVGEPRVGKTSLIMSLVSEEFPEEVPPRAEEITIPADVTPERVPTHIVDYSEAEQS 77
           ++ ++VG+  VGKT L++S  +  FP E  P   +    A+V  +  P ++  +  A Q 
Sbjct: 488 IKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFD-NYSANVMVDSKPINLGLWDTAGQE 312

Query: 78  DEQLHQEIS--QANVICIVYAVNNKHSIDKVTSRWIPLINERTDKDSRLPLILVGNKSDL 135
           D    + +S  Q +V  I +++ +  S + V ++W P ++         P+ILVG K DL
Sbjct: 311 DYDRLRPLSYPQTDVFLICFSLISPASFENVKAKWYPEVSHHC---PNTPIILVGTKLDL 141

Query: 136 VE 137
            E
Sbjct: 140 RE 135
>19006
          Length = 568

 Score = 49.3 bits (116), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 31/118 (26%), Positives = 59/118 (50%), Gaps = 1/118 (0%)
 Frame = -2

Query: 19  RILLVGEPRVGKTSLIMSLVSEEFPE-EVPPRAEEITIPADVTPERVPTHIVDYSEAEQS 77
           ++++VG+   GKT L++    ++FPE  VP   E      +V  ++V   + D +  E  
Sbjct: 432 KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDSKQVELALWDTAGQEDY 253

Query: 78  DEQLHQEISQANVICIVYAVNNKHSIDKVTSRWIPLINERTDKDSRLPLILVGNKSDL 135
           D          +VI + +++++  S++ +  +W P +         +P+ILVGNK DL
Sbjct: 252 DRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVRHFC---PNVPIILVGNKKDL 88
>26083
          Length = 432

 Score = 41.2 bits (95), Expect = 0.001,   Method: Composition-based stats.
 Identities = 33/124 (26%), Positives = 60/124 (48%), Gaps = 7/124 (5%)
 Frame = +1

Query: 16  KDVRILLVGEPRVGKTSLIMSLVSEEFPEEVPPRAEEITIPAD-------VTPERVPTHI 68
           +  +++ +GE  VGKTSLI   + + F         + TI  D       +    +   +
Sbjct: 73  RKFKLVFLGEQSVGKTSLITRFMYDSFDN-----TYQATIGIDFLSKTMYLEDRTIRLQL 237

Query: 69  VDYSEAEQSDEQLHQEISQANVICIVYAVNNKHSIDKVTSRWIPLINERTDKDSRLPLIL 128
            D +  E+    +   I  ++V  +VY + N +S  + TS+WI  +  RT++ S + ++L
Sbjct: 238 WDTAGQERFRSLIPSYIRDSSVAVVVYDITNANSFHQ-TSKWIDDV--RTERGSDVIIML 408

Query: 129 VGNK 132
           VGNK
Sbjct: 409 VGNK 420
>34468
          Length = 1502

 Score = 40.8 bits (94), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 38/151 (25%), Positives = 69/151 (45%), Gaps = 8/151 (5%)
 Frame = +1

Query: 3   AGRVRPLRASDMKKDVRILLVGEPRVGKTSLIMSLVSEEFPEEVPPRAEEITIPAD---- 58
           AG ++ +     ++  +I+++G+  VGKT L       +FP++      E TI  D    
Sbjct: 451 AGAMKVVEKQTQRRIFKIIVIGDSNVGKTCLTYRFCLGKFPDKT-----EATIGVDFREK 615

Query: 59  ---VTPERVPTHIVDYSEAEQSDEQLHQE-ISQANVICIVYAVNNKHSIDKVTSRWIPLI 114
              V  E +   + D +  E+  + + Q      + +  VY +    S + + + WI   
Sbjct: 616 SIQVDSEHLKLQLWDTAGQERFRKSMVQHYYRNVHAVVFVYDMTKMSSFENMPA-WIEEC 792

Query: 115 NERTDKDSRLPLILVGNKSDLVEYSSMETIL 145
            +R +    +P ILVGNK D+VE  ++ T L
Sbjct: 793 -DRHNLTKYIPRILVGNKCDVVERIAVNTNL 882

 Score = 36.2 bits (82), Expect = 0.045,   Method: Compositional matrix adjust.
 Identities = 39/157 (24%), Positives = 63/157 (40%), Gaps = 15/157 (9%)
 Frame = +1

Query: 424 KKQTQRNVFRCNVIGVKGCGKTGV------------LQSLLGRNLMRQKKIRDDHKSYYA 471
           +KQTQR +F+  VIG    GKT +             ++ +G +  R+K I+ D   +  
Sbjct: 472 EKQTQRRIFKIIVIGDSNVGKTCLTYRFCLGKFPDKTEATIGVDF-REKSIQVD-SEHLK 645

Query: 472 INTVYVYGQEKYLLLHDISESEFLTEAETICDVVCLVYDVTNPKSFEYCARIFKQ---HF 528
           +      GQE++           +         V  VYD+T   SFE      ++   H 
Sbjct: 646 LQLWDTAGQERF-------RKSMVQHYYRNVHAVVFVYDMTKMSSFENMPAWIEECDRHN 804

Query: 529 MDSRIPCLIVAAKSDLHEVKQEHSISPTDFCRKHKMP 565
           +   IP ++V  K D+ E    ++     F   H MP
Sbjct: 805 LTKYIPRILVGNKCDVVERIAVNTNLAQKFADAHNMP 915
>30760
          Length = 596

 Score = 37.0 bits (84), Expect = 0.024,   Method: Compositional matrix adjust.
 Identities = 39/158 (24%), Positives = 65/158 (41%), Gaps = 9/158 (5%)
 Frame = -1

Query: 433 RCNVIGVKGCGKTGVLQSLLGRNLMRQKKIRDDHKSYYAINTVYV--YGQEKYLLLHDIS 490
           +C V G  G GK+ + Q     +    K           +  V +     +  L L D +
Sbjct: 524 KCIVTGDSGVGKSSICQVFHSDSAHFPKNYSMTTGVEVLVKLVNIPDSRDQVELYLFDSA 345

Query: 491 ESEFLTEAETIC----DVVCLVYDVTNPKSFEYCARIFKQHFM---DSRIPCLIVAAKSD 543
             E  +E  T       VV +VYDVT+  SF  C R  ++      ++ IP ++VA K+D
Sbjct: 344 GKEIFSENVTKFWDQPSVVMVVYDVTDETSFSGCVRWLERVRAAKPNTVIPGVLVANKTD 165

Query: 544 LHEVKQEHSISPTDFCRKHKMPPPQAFTCNTADAPSKD 581
           L E ++       D  + H +   + F C+  +  + D
Sbjct: 164 LDERRRVSRKEGKDLAQSHGL---EYFECSAKEMQNTD 60
>17511
          Length = 483

 Score = 34.3 bits (77), Expect = 0.17,   Method: Compositional matrix adjust.
 Identities = 30/130 (23%), Positives = 60/130 (46%), Gaps = 3/130 (2%)
 Frame = -3

Query: 9   LRASDMKKDVRILLVGEPRVGKTSLIMSLVSEEFPEEVPPR--AEEITIPADVTPERVPT 66
           + AS  K  ++++++G+  VGKTSL+   V+++F  +      A+ +T    V    V  
Sbjct: 391 IMASRKKVLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTM 212

Query: 67  HIVDYSEAEQSDEQLHQEISQANVICIVYAVNNKHSIDKVTSRWIPLINERTDKD-SRLP 125
            I D +  E+           A+   +V+ V   ++   + S     + + + +D    P
Sbjct: 211 QIWDTAGQERFQSLGVAFYRGADCCVLVFDVTMPNTFRSLDSWRDEFLIQASPRDPENFP 32

Query: 126 LILVGNKSDL 135
            +++GNK DL
Sbjct: 31  FVVIGNKIDL 2
>10708
          Length = 2775

 Score = 33.5 bits (75), Expect = 0.25,   Method: Compositional matrix adjust.
 Identities = 26/89 (29%), Positives = 41/89 (46%), Gaps = 13/89 (14%)
 Frame = -3

Query: 124  LPLILVGNKSDLVEYSSMETIL------PI-------MNQYTEIETCVECSAKNLKNISE 170
            +P+ILVGNK DL    + +  L      P+       M++     + +ECSAK  + + E
Sbjct: 2551 VPIILVGNKKDLRNDENTKRELMKMKQEPVRLDEGRAMSEKINAYSYLECSAKTKEGVRE 2372

Query: 171  LFYYAQKAVLHPTGPLYCPEEKEMKPACI 199
            +F  A +A L          +K+ K  CI
Sbjct: 2371 VFETATRAALQT--------KKKKKGGCI 2309
>09827
          Length = 1201

 Score = 32.3 bits (72), Expect = 0.62,   Method: Compositional matrix adjust.
 Identities = 27/121 (22%), Positives = 49/121 (40%)
 Frame = -3

Query: 15   KKDVRILLVGEPRVGKTSLIMSLVSEEFPEEVPPRAEEITIPADVTPERVPTHIVDYSEA 74
            KKD+RIL+VG    GKT+++  L   E    +P     +     V  + +   + D    
Sbjct: 1121 KKDMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNV---ETVEYKNISFTVWDVGGQ 951

Query: 75   EQSDEQLHQEISQANVICIVYAVNNKHSIDKVTSRWIPLINERTDKDSRLPLILVGNKSD 134
            ++              +  V   N+K  + +       ++NE   +D+   L++  NK D
Sbjct: 950  DKIRPLWRHYFQNTQGLIFVVDSNDKERVQEAREELTRMLNEDELRDA--VLLVFANKQD 777

Query: 135  L 135
            L
Sbjct: 776  L 774
>17872
          Length = 700

 Score = 32.0 bits (71), Expect = 0.81,   Method: Compositional matrix adjust.
 Identities = 27/100 (27%), Positives = 45/100 (45%), Gaps = 14/100 (14%)
 Frame = -1

Query: 87  QANVICIVYAVNNKHSIDKVTSRWIPLINERTDKDSRLPLILVGNKSDL-------VEYS 139
           + NV  + ++V +  S   V  +W+P +          PL++VG +SDL       +E +
Sbjct: 661 ETNVFLLCFSVVSPTSFHNVMEKWVPELRYHCPG---APLVVVGTQSDLRNDVKVLIELA 491

Query: 140 -------SMETILPIMNQYTEIETCVECSAKNLKNISELF 172
                  S E  + + +Q       VECSA   KN+ E+F
Sbjct: 490 KYKEKPVSEEEAVKMADQLGA--QYVECSALTQKNLKEVF 377
>08153
          Length = 1703

 Score = 31.6 bits (70), Expect = 1.0,   Method: Compositional matrix adjust.
 Identities = 37/154 (24%), Positives = 58/154 (37%), Gaps = 1/154 (0%)
 Frame = +1

Query: 15  KKDVRILLVGEPRVGKTSLIMSLVSEEFPEEVPPRAEEITIPADVTPERVPTHIVDYSEA 74
           KK+VRIL+VG    GKT+++  L   E    +P     +     V  + +   + D    
Sbjct: 76  KKEVRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVET---VEYKNISFTVWDVGGQ 246

Query: 75  EQSDEQLHQEISQANVICIVYAVNNKHSIDKVTSRWIPLINERTDKDSRLPLILV-GNKS 133
           ++              +  V   N++  I++       ++NE    D R  +ILV  NK 
Sbjct: 247 DKIRPLWRHYFQNTQGLIFVVDSNDRERINEAKEELARMLNE---DDLRDAIILVFANKQ 417

Query: 134 DLVEYSSMETILPIMNQYTEIETCVECSAKNLKN 167
           D          LP  N Y+  E        NLK 
Sbjct: 418 D----------LP--NAYSASEVTAHLGLANLKG 483
>12605
          Length = 480

 Score = 31.2 bits (69), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 14/39 (35%), Positives = 20/39 (51%)
 Frame = +3

Query: 351 YIPWGPDVNNTVCTNERGWITYQGFLSQWTLTTYLDVQR 389
           Y+PW   +   +C      +TYQGFLS  +L  Y   Q+
Sbjct: 261 YLPWQTRLTEIICVPSHKGLTYQGFLS--SLQVYASTQQ 371
>17337
          Length = 518

 Score = 30.8 bits (68), Expect = 1.8,   Method: Composition-based stats.
 Identities = 18/50 (36%), Positives = 26/50 (52%), Gaps = 4/50 (8%)
 Frame = +1

Query: 191 EKEMKPACIKALTRIFKISDQDNDGTLNDAELNF----FQRICFNTPLAP 236
           EKE+ P C+ A+  I K  D +N   LN  +++     F  ICF   L+P
Sbjct: 295 EKEVGPNCLTAMKTIKKAFDPNN--ILNPGKISL*RETFTIICFKRKLSP 438
>13901
          Length = 962

 Score = 30.4 bits (67), Expect = 2.2,   Method: Compositional matrix adjust.
 Identities = 13/40 (32%), Positives = 24/40 (60%)
 Frame = -3

Query: 19  RILLVGEPRVGKTSLIMSLVSEEFPEEVPPRAEEITIPAD 58
           +++++G+P VGKTS +   V++ F      R  ++TI  D
Sbjct: 282 KVIIIGDPTVGKTSFVQRYVNDSF-----RRDYKMTIGVD 178
>18208
          Length = 458

 Score = 29.6 bits (65), Expect = 3.9,   Method: Compositional matrix adjust.
 Identities = 14/33 (42%), Positives = 22/33 (66%)
 Frame = -1

Query: 16  KDVRILLVGEPRVGKTSLIMSLVSEEFPEEVPP 48
           +++RILL+G    GKT+L+  L SE+ P  + P
Sbjct: 305 RELRILLLGLDNAGKTTLLKQLASED-PSHITP 210
>28329
          Length = 373

 Score = 29.6 bits (65), Expect = 4.1,   Method: Compositional matrix adjust.
 Identities = 11/28 (39%), Positives = 19/28 (67%)
 Frame = +3

Query: 10  RASDMKKDVRILLVGEPRVGKTSLIMSL 37
           R   ++  V + ++GEP VGK+SL+ +L
Sbjct: 198 RGERLRDGVHLAIIGEPNVGKSSLLNTL 281
>04057
          Length = 1327

 Score = 28.5 bits (62), Expect = 7.9,   Method: Compositional matrix adjust.
 Identities = 17/37 (45%), Positives = 18/37 (48%)
 Frame = +3

Query: 442  CGKTGVLQSLLGRNLMRQKKIRDDHKSYYAINTVYVY 478
            C    V  SL  RN    KK RD H  YY  N VY+Y
Sbjct: 1047 CFVHSVYMSLAYRNWGGDKKKRDIHPLYYLQNIVYMY 1157
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6677983|ref|NP_033217.1| suppressor of K+ transport
defect 3 [Mus musculus]
         (677 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

14005                                                                  51   1e-06
33737                                                                  50   4e-06
06253                                                                  49   7e-06
05924                                                                  48   1e-05
21532                                                                  45   7e-05
13462                                                                  43   4e-04
27108                                                                  43   5e-04
08473                                                                  41   0.002
28494                                                                  40   0.004
16561                                                                  39   0.006
18216                                                                  39   0.008
25470                                                                  39   0.008
28113                                                                  39   0.009
20792                                                                  37   0.024
01642                                                                  37   0.033
11295                                                                  36   0.050
20036                                                                  36   0.054
12417                                                                  34   0.20 
09292                                                                  33   0.38 
19166                                                                  33   0.47 
11861                                                                  32   0.64 
22305                                                                  32   0.64 
09214                                                                  32   0.75 
33144                                                                  32   0.80 
02564                                                                  32   0.96 
28691                                                                  32   1.2  
27434                                                                  32   1.2  
00540                                                                  31   1.5  
22269                                                                  31   1.8  
02114                                                                  30   2.5  
09180                                                                  30   2.6  
06853                                                                  30   2.6  
05396                                                                  29   5.4  
15772                                                                  29   5.7  
>14005
          Length = 1745

 Score = 51.2 bits (121), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 45/148 (30%), Positives = 66/148 (44%), Gaps = 1/148 (0%)
 Frame = -1

Query: 141  AARANNVQEVRRLLSEGADVNARHKLGWTALMVASISHNESVVQVLLAAGADPNLGDEFS 200
            A +  N++ ++RL+  GADV+  +  G TAL VAS+   +  V  LL             
Sbjct: 1319 ACQRPNIELLKRLVLHGADVDKPNAKGHTALHVASVRGFKQHVIYLL------------- 1179

Query: 201  SVYKTANEQGVHSLEVLVTREDDFNNRLNHRASFKGCTALHYAVLADDYSIVKELLDRGA 260
                                  DF +   + A+ KG  ALH A       +V+ LL +GA
Sbjct: 1178 ----------------------DFCDAEVNAATLKGNNALHIACRGKHADLVELLLHKGA 1065

Query: 261  NPLQRNEMGHTPLDYA-REGEVMKLLKT 287
            NP QRN+ G TP + A R  EV+ +L +
Sbjct: 1064 NPAQRNQRGWTPRNSAGRCXEVLDILDS 981
>33737
          Length = 965

 Score = 49.7 bits (117), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 27/77 (35%), Positives = 42/77 (54%)
 Frame = -1

Query: 409 LTKKLKQCPNAVVLFDEVDKAHPDVLTIMLQLFDEGRLTDGKGKTIDCKDAIFIMTSNVA 468
           + K++ +CP ++ +FDEVDK    +L  +    D     DG    +D + AIFI  SN  
Sbjct: 398 IEKQVIKCPQSMFIFDEVDKMPSGLLDTIKPYLDYHEQLDG----VDYRRAIFIFLSNAG 231

Query: 469 SDEIAQHALQLRQEALE 485
            D I +HALQ  +E ++
Sbjct: 230 GDAITKHALQQWREGVK 180
>06253
          Length = 1049

 Score = 48.9 bits (115), Expect = 7e-06,   Method: Compositional matrix adjust.
 Identities = 50/174 (28%), Positives = 80/174 (45%), Gaps = 2/174 (1%)
 Frame = -1

Query: 115 MWALAMALVVQCYSKNPSNKDAALMEAARANNVQEVRRLLSEGADVNARHKLGWTALMVA 174
           M AL   L V C++ +   K   L  AA  N  + V+ LL  GADV+A+ K G   L  A
Sbjct: 641 MMALLTPLNVNCHASD-GRKSTPLHLAAGYNRTRIVQLLLQHGADVHAKDKGGLVPLHNA 465

Query: 175 SISHNESVVQVLLAAGADPNLGD--EFSSVYKTANEQGVHSLEVLVTREDDFNNRLNHRA 232
               +  V ++LL AGA  N  D  +F+ +++ A++  V    +L+    D N    H  
Sbjct: 464 CSYGHFEVTEMLLXAGASVNAVDLWQFTPLHEAASKSRVEVCSLLLAHGADPNLVNCHSK 285

Query: 233 SFKGCTALHYAVLADDYSIVKELLDRGANPLQRNEMGHTPLDYAREGEVMKLLK 286
           S              D +  +EL +R    +Q    GH+ L+ AR+ ++ ++ K
Sbjct: 284 SII------------DVAPTRELQER----IQFEYKGHSLLEGARQADLARVKK 171

 Score = 38.1 bits (87), Expect = 0.012,   Method: Compositional matrix adjust.
 Identities = 41/127 (32%), Positives = 50/127 (39%)
 Frame = -1

Query: 150 VRRLLSEGADVNARHKLGWTALMVASISHNESVVQVLLAAGADPNLGDEFSSVYKTANEQ 209
           V  LL  GA+V+AR   G   L  A    +  VVQ+LL  GADPN               
Sbjct: 998 VEHLLENGANVHARDDGGLIPLHNACSFGHAEVVQLLLRHGADPN--------------- 864

Query: 210 GVHSLEVLVTREDDFNNRLNHRASFKGCTALHYAVLADDYSIVKELLDRGANPLQRNEMG 269
                       D++N    H A+ KG           D  IV  LL + A+P  RN  G
Sbjct: 863 ----------ARDNWNYTPLHEAAIKGKI---------DVCIV--LLQQCADPNIRNTDG 747

Query: 270 HTPLDYA 276
            T LD A
Sbjct: 746 KTALDLA 726
>05924
          Length = 704

 Score = 47.8 bits (112), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 40/140 (28%), Positives = 68/140 (48%), Gaps = 2/140 (1%)
 Frame = +1

Query: 148 QEVRRLLSEGADVNARHKLGWTALMVASISHNESVVQVLLAAGADPNLG--DEFSSVYKT 205
           + V+RL+  G DVNAR     T L  A    +E +VQ+L+ AGA+ N    D  ++++  
Sbjct: 7   KAVQRLVKGGVDVNARFWYDSTLLHEAVSMASEDLVQMLIKAGANANSTNQDGRTALHLA 186

Query: 206 ANEQGVHSLEVLVTREDDFNNRLNHRASFKGCTALHYAVLADDYSIVKELLDRGANPLQR 265
                 + +++L+    D N R     +  G T LH AV      +V +L++ GA+    
Sbjct: 187 CRGGYTNIVQILIAAGTDVNRR-----TVDGKTCLHVAVWRGHTEVVVKLVNAGADVNIP 351

Query: 266 NEMGHTPLDYAREGEVMKLL 285
           + +G +PL +A       +L
Sbjct: 352 DSVGCSPLYWAARSNYTAIL 411

 Score = 46.2 bits (108), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 49/147 (33%), Positives = 68/147 (46%), Gaps = 4/147 (2%)
 Frame = +1

Query: 118 LAMALVVQCYSKNPSNKDA--ALMEAARANNVQEVRRLLSEGADVNARHKLGWTALMVAS 175
           L   L+    + N +N+D   AL  A R      V+ L++ G DVN R   G T L VA 
Sbjct: 109 LVQMLIKAGANANSTNQDGRTALHLACRGGYTNIVQILIAAGTDVNRRTVDGKTCLHVAV 288

Query: 176 ISHNESVVQVLLAAGADPNLGDEF--SSVYKTANEQGVHSLEVLVTREDDFNNRLNHRAS 233
              +  VV  L+ AGAD N+ D    S +Y  A       L VLV    +   ++N+R  
Sbjct: 289 WRGHTEVVVKLVNAGADVNIPDSVGCSPLYWAARSNYTAILTVLV----NAGAKVNYRVK 456

Query: 234 FKGCTALHYAVLADDYSIVKELLDRGA 260
            K  T LH A+      +V+ LL +GA
Sbjct: 457 SK-WTPLHAALHLGHMGVVRYLLLQGA 534

 Score = 33.1 bits (74), Expect = 0.36,   Method: Compositional matrix adjust.
 Identities = 23/58 (39%), Positives = 31/58 (53%)
 Frame = +1

Query: 138 LMEAARANNVQEVRRLLSEGADVNARHKLGWTALMVASISHNESVVQVLLAAGADPNL 195
           L  AAR+N    +  L++ GA VN R K  WT L  A    +  VV+ LL  GA+ N+
Sbjct: 373 LYWAARSNYTAILTVLVNAGAKVNYRVKSKWTPLHAALHLGHMGVVRYLLLQGAETNI 546
>21532
          Length = 460

 Score = 45.4 bits (106), Expect = 7e-05,   Method: Compositional matrix adjust.
 Identities = 41/133 (30%), Positives = 56/133 (42%)
 Frame = -1

Query: 146 NVQEVRRLLSEGADVNARHKLGWTALMVASISHNESVVQVLLAAGADPNLGDEFSSVYKT 205
           NV  +  LLS GADVN R   G T    A    N + V+ LL  G  P+      +V   
Sbjct: 460 NVPIINTLLSHGADVNIRDNTGCTPFANACCLGNLAAVKALLTPGESPSWSKPMINV--- 290

Query: 206 ANEQGVHSLEVLVTREDDFNNRLNHRASFKGCTALHYAVLADDYSIVKELLDRGANPLQR 265
                         R++  N  L H AS +G TA           IV+ L++  A+   +
Sbjct: 289 --------------RDNSQNTPL-HLASQEGHTA-----------IVELLVEHKADLAAK 188

Query: 266 NEMGHTPLDYARE 278
           N+ GH PL  AR+
Sbjct: 187 NDSGHNPLSLARQ 149
>13462
          Length = 1388

 Score = 43.1 bits (100), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 53/192 (27%), Positives = 83/192 (43%), Gaps = 28/192 (14%)
 Frame = +3

Query: 113 LGMWALAMALVVQCYSKNPSNKD----AALMEAARANNVQEVRRLLSEGADVNARHKLGW 168
           LG+ ++ +A     Y   P+ +D     AL  A   +NV  VR LL  G DV        
Sbjct: 222 LGIVSMLLA-----YGAQPNVQDEDGNTALHLACSESNVDVVRLLLEWGGDVAVADIDNE 386

Query: 169 TALMVASISHNESVVQVLLAAGADPNL--GDEFSSVYKTANEQGVHSL-----EVLVTRE 221
           T L+ A ++++  +V +LL AG+DPN   G     V +  + + +  L     +V     
Sbjct: 387 TPLVRACLANSVELVDLLLHAGSDPNHSHGRPLEIVVRAPSLESLKLLIGAGAQVTGNTY 566

Query: 222 DDFNNRLNHRASFK---------------GCTALHYAVLADD--YSIVKELLDRGANPLQ 264
             F +  N+    K               G TALH+A ++ +  +  V+ LL  G+NP  
Sbjct: 567 LSFASEHNYLDMMKVLHNYGVDVNGTGRLGLTALHHACISQEATHDAVRLLLLWGSNPNL 746

Query: 265 RNEMGHTPLDYA 276
               G TPL +A
Sbjct: 747 VTGTGDTPLHFA 782

 Score = 30.8 bits (68), Expect = 1.7,   Method: Compositional matrix adjust.
 Identities = 26/86 (30%), Positives = 41/86 (47%), Gaps = 2/86 (2%)
 Frame = +3

Query: 179 NESVVQVLLAAGADPNLGDE--FSSVYKTANEQGVHSLEVLVTREDDFNNRLNHRASFKG 236
           N  +V +LLA GA PN+ DE   ++++   +E  V  + +L+    D        A    
Sbjct: 219 NLGIVSMLLAYGAQPNVQDEDGNTALHLACSESNVDVVRLLLEWGGDVA-----VADIDN 383

Query: 237 CTALHYAVLADDYSIVKELLDRGANP 262
            T L  A LA+   +V  LL  G++P
Sbjct: 384 ETPLVRACLANSVELVDLLLHAGSDP 461
>27108
          Length = 449

 Score = 42.7 bits (99), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 43/140 (30%), Positives = 67/140 (47%), Gaps = 3/140 (2%)
 Frame = -3

Query: 138 LMEAARANNVQEVRRLLS-EGADVNARHKLGWTALMVASISHNESVVQVLLAAGADPNLG 196
           L+ AA  NN+  ++ LL+  G D+N++   GWTAL  A    +    + LL       L 
Sbjct: 375 LIRAAIKNNLSLLKHLLTVPGVDINSQDYAGWTALHEACNHGHLECARALLKFVPSATL- 199

Query: 197 DEFSSVYKTANEQGVHSLEVLVTREDDFNNRLNHRASFKGCTALHYAVLADDYSIVKELL 256
           D F   +++   +G         R+ D      H A+ +G TALH AV  +  S+VK LL
Sbjct: 198 DSF---FQSGKNRG-------KVRKVDM-----HLANQEGITALHDAVSMNHVSVVKLLL 64

Query: 257 DRGANPLQRNEM--GHTPLD 274
             G + L +++   G T +D
Sbjct: 63  KYGGSSLLKDKTVSGDTVMD 4
>08473
          Length = 942

 Score = 40.8 bits (94), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 24/60 (40%), Positives = 33/60 (55%)
 Frame = -1

Query: 138 LMEAARANNVQEVRRLLSEGADVNARHKLGWTALMVASISHNESVVQVLLAAGADPNLGD 197
           L  AA    +   + L+ +GA+VNA  K+  T LMVA+   N   V+ LL  GA+PN  D
Sbjct: 807 LFYAAHRGEISICKLLVDKGANVNAADKMLITPLMVAAREGNREAVEFLLKRGANPNTAD 628

 Score = 35.4 bits (80), Expect = 0.077,   Method: Compositional matrix adjust.
 Identities = 24/51 (47%), Positives = 26/51 (50%), Gaps = 3/51 (5%)
 Frame = -1

Query: 238 TALHYAVLADDYSIVKELLDRGANPLQRNEMGHTPLDY-AREGE--VMKLL 285
           TALH+A     Y  V  LL  GANP      G TPL Y A  GE  + KLL
Sbjct: 912 TALHHACAGLHYGCVHALLQGGANPTCMEMGGKTPLFYAAHRGEISICKLL 760

 Score = 31.6 bits (70), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 35/121 (28%), Positives = 52/121 (42%), Gaps = 3/121 (2%)
 Frame = -1

Query: 159 DVNARHKLGWTALMVASISHNESVVQVLLAAGADPN---LGDEFSSVYKTANEQGVHSLE 215
           DV+ R     TAL  A    +   V  LL  GA+P    +G + + ++  A+   +   +
Sbjct: 942 DVDMRDSNDMTALHHACAGLHYGCVHALLQGGANPTCMEMGGK-TPLFYAAHRGEISICK 766

Query: 216 VLVTREDDFNNRLNHRASFKGCTALHYAVLADDYSIVKELLDRGANPLQRNEMGHTPLDY 275
           +LV +  + N      A     T L  A    +   V+ LL RGANP   +  GH  L Y
Sbjct: 765 LLVDKGANVN-----AADKMLITPLMVAAREGNREAVEFLLKRGANPNTADREGHLALYY 601

Query: 276 A 276
           A
Sbjct: 600 A 598

 Score = 29.3 bits (64), Expect = 5.1,   Method: Compositional matrix adjust.
 Identities = 21/45 (46%), Positives = 26/45 (57%), Gaps = 1/45 (2%)
 Frame = -1

Query: 236 GCTALHYAVLADDYSIVKELLDRGANPLQRNEMGHTPLDY-AREG 279
           G T L YA    + SI K L+D+GAN    ++M  TPL   AREG
Sbjct: 819 GKTPLFYAAHRGEISICKLLVDKGANVNAADKMLITPLMVAAREG 685
>28494
          Length = 463

 Score = 39.7 bits (91), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 21/62 (33%), Positives = 33/62 (53%)
 Frame = -1

Query: 136 AALMEAARANNVQEVRRLLSEGADVNARHKLGWTALMVASISHNESVVQVLLAAGADPNL 195
              + A  + +  EV++LL  GAD+N  +  G TAL  A I  N  +V+ L+   AD ++
Sbjct: 313 CVFLAACSSGDRDEVKKLLERGADINTANVDGLTALHQACIDDNLDMVEFLVEQNADVDV 134

Query: 196 GD 197
            D
Sbjct: 133 CD 128

 Score = 30.8 bits (68), Expect = 1.7,   Method: Compositional matrix adjust.
 Identities = 20/65 (30%), Positives = 31/65 (47%), Gaps = 2/65 (3%)
 Frame = -1

Query: 130 NPSNKDA--ALMEAARANNVQEVRRLLSEGADVNARHKLGWTALMVASISHNESVVQVLL 187
           N +N D   AL +A   +N+  V  L+ + ADV+     GWT L   +      + + LL
Sbjct: 238 NTANVDGLTALHQACIDDNLDMVEFLVEQNADVDVCDNEGWTPLHATASCGFTEIARYLL 59

Query: 188 AAGAD 192
             GA+
Sbjct: 58  ENGAN 44
>16561
          Length = 2029

 Score = 38.9 bits (89), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 28/85 (32%), Positives = 43/85 (50%), Gaps = 2/85 (2%)
 Frame = -3

Query: 135  DAALMEAARANNVQEVRRLLSEGADVNARHKLGWTALMVASISHNESVVQVLLAAGADPN 194
            D AL  +A  N    ++ LLS+GA +NA +  G + L VA    +   V VLL  G D N
Sbjct: 2009 DTALHYSAFGNQPDVLQLLLSKGAKINALNNGGCSTLHVAVNKQHIKCVHVLLNXGCDVN 1830

Query: 195  LGDEF--SSVYKTANEQGVHSLEVL 217
              D +  ++++    ++ V SL  L
Sbjct: 1829 XQDAYGDTALHDAIGKRAVKSLTSL 1755
>18216
          Length = 472

 Score = 38.5 bits (88), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 20/43 (46%), Positives = 27/43 (62%)
 Frame = +2

Query: 153 LLSEGADVNARHKLGWTALMVASISHNESVVQVLLAAGADPNL 195
           +L +G  VNA    GWTA M A+   + +VVQ LL AGAD ++
Sbjct: 263 VLDKGVHVNAVDPFGWTAAMSAAFEGHLAVVQTLLEAGADLSV 391
>25470
          Length = 400

 Score = 38.5 bits (88), Expect = 0.008,   Method: Composition-based stats.
 Identities = 37/127 (29%), Positives = 47/127 (37%)
 Frame = -3

Query: 150 VRRLLSEGADVNARHKLGWTALMVASISHNESVVQVLLAAGADPNLGDEFSSVYKTANEQ 209
           V  LL  GA+V+AR   G   L  A    +  VVQ+LL  GADPN  D ++         
Sbjct: 350 VEHLLENGANVHARDDGGLIPLHNACSFGHAEVVQLLLRHGADPNARDNWNY-------- 195

Query: 210 GVHSLEVLVTREDDFNNRLNHRASFKGCTALHYAVLADDYSIVKELLDRGANPLQRNEMG 269
                                       T LH A +     +   LL + A+P  RN  G
Sbjct: 194 ----------------------------TPLHEAAIKGKIDVCIVLLQQCADPNIRNTDG 99

Query: 270 HTPLDYA 276
            T LD A
Sbjct: 98  KTALDLA 78

 Score = 36.2 bits (82), Expect = 0.045,   Method: Composition-based stats.
 Identities = 23/58 (39%), Positives = 29/58 (50%)
 Frame = -3

Query: 138 LMEAARANNVQEVRRLLSEGADVNARHKLGWTALMVASISHNESVVQVLLAAGADPNL 195
           L  A    + + V+ LL  GAD NAR    +T L  A+I     V  VLL   ADPN+
Sbjct: 287 LHNACSFGHAEVVQLLLRHGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQQCADPNI 114
>28113
          Length = 449

 Score = 38.5 bits (88), Expect = 0.009,   Method: Compositional matrix adjust.
 Identities = 20/58 (34%), Positives = 31/58 (53%)
 Frame = -3

Query: 138 LMEAARANNVQEVRRLLSEGADVNARHKLGWTALMVASISHNESVVQVLLAAGADPNL 195
           L  +A   +V  V+ LL+ G   + +  + W A+  AS   +  VV++LL AG  PNL
Sbjct: 321 LHASAAQGDVHHVQSLLNHGHHHSKKDSIAWAAIHYASWYGSADVVEILLDAGCSPNL 148
>20792
          Length = 441

 Score = 37.0 bits (84), Expect = 0.024,   Method: Composition-based stats.
 Identities = 26/80 (32%), Positives = 38/80 (47%), Gaps = 2/80 (2%)
 Frame = +2

Query: 138 LMEAARANNVQEVRRLLSEGADVNARHKLGWTALMVASISHNESVVQVLLAAGADPNL-- 195
           L E A+   +  +  LL  G  V+   +  WT LM+A       V+ +LL  GADP L  
Sbjct: 89  LHETAQFGQLDCMNFLLQRGVQVDCLKRADWTPLMLACTKCQLPVISLLLKHGADPALVN 268

Query: 196 GDEFSSVYKTANEQGVHSLE 215
            D ++S +  A E  V  L+
Sbjct: 269 KDGWNSFHIAAREGHVDILK 328
>01642
          Length = 1406

 Score = 36.6 bits (83), Expect = 0.033,   Method: Compositional matrix adjust.
 Identities = 39/137 (28%), Positives = 59/137 (43%), Gaps = 11/137 (8%)
 Frame = -1

Query: 344 PLVFLFLGSSGIGKTELAKQTAKYMHKDAKKGFIRLDMSEFQERHEVAKFIGSPPGYIGH 403
           P   L  G  G GKT LAK  A +        FIR+  SEF     V K++G  P  +  
Sbjct: 893 PRGVLMYGPPGCGKTMLAKAVAHH----TTAAFIRVVGSEF-----VQKYLGEGPRMV-- 747

Query: 404 EEGGQLTKKLKQCPNAVVLFDEVDK-----------AHPDVLTIMLQLFDEGRLTDGKGK 452
                + +  K+   A++  DE+D            A  +V  I+L+L ++    DG  +
Sbjct: 746 ---RDVFRLAKENAPAIIFIDEIDAIATKRFDAQTGADREVQRILLELLNQ---MDGFDQ 585

Query: 453 TIDCKDAIFIMTSNVAS 469
           T++ K    IM +N A 
Sbjct: 584 TVNVK---VIMATNRAD 543
>11295
          Length = 1179

 Score = 36.2 bits (82), Expect = 0.050,   Method: Compositional matrix adjust.
 Identities = 43/147 (29%), Positives = 55/147 (37%), Gaps = 4/147 (2%)
 Frame = +1

Query: 148 QEVRRLLSEGADVNARHKLGWTALMVASISHNESVVQVLLAAGADPNLGDEFSSVYKTAN 207
           Q V  LL  GA +      G +AL  A I  N  V ++LL    D   GD  + V  T+N
Sbjct: 7   QTVLTLLQGGAQIYWTDHRGLSALHHACIGRNTEVAELLL----DGWNGDGIA-VNATSN 171

Query: 208 EQGVHSLEVLVTREDDFNNRLNHRASFKGCTALHYAVLADDYSIVKELLDRGANPLQRNE 267
           +                             TALH A   DD  +   LL  GA  +  + 
Sbjct: 172 DH---------------------------VTALHIACCLDDREMASLLLKYGAYAMALDV 270

Query: 268 MGHTPLDYA----REGEVMKLLKTSET 290
           +GHTPL  A     EG    LL  S+ 
Sbjct: 271 IGHTPLHVACWCGSEGVTRLLLDRSDV 351
>20036
          Length = 1849

 Score = 35.8 bits (81), Expect = 0.054,   Method: Compositional matrix adjust.
 Identities = 31/92 (33%), Positives = 44/92 (47%), Gaps = 2/92 (2%)
 Frame = +3

Query: 137  ALMEAARANNVQEVRRLLSEGADVNARHKLGWTALMVASISHNESVVQVLLAA-GADPNL 195
            ALM A        V  LL  GAD N +   G TALM A    + ++VQ+LLA    D  L
Sbjct: 1110 ALMLATSQCRTDMVELLLETGADCNQQDFDGSTALMCACEHGHTAIVQLLLAQPHCDATL 1289

Query: 196  GD-EFSSVYKTANEQGVHSLEVLVTREDDFNN 226
             D E S+    A E     + V++ +  +F++
Sbjct: 1290 TDNENSTALSIAMEASHKDIGVILYKHLNFSS 1385

 Score = 33.5 bits (75), Expect = 0.32,   Method: Compositional matrix adjust.
 Identities = 33/105 (31%), Positives = 47/105 (44%), Gaps = 2/105 (1%)
 Frame = +3

Query: 108  PNKTGLGMWALAMALVVQCYSKNPSNKDAALMEAARANNVQEVRRLLSEGADVNA-RHKL 166
            PNK G     LA    +Q    N  ++D              +R+L   G D+NA   + 
Sbjct: 975  PNKAGYTPTMLASLAFIQ----NDDHRDI-------------IRQLFLAG-DINACAEQT 1100

Query: 167  GWTALMVASISHNESVVQVLLAAGADPNLGD-EFSSVYKTANEQG 210
            G TALM+A+      +V++LL  GAD N  D + S+    A E G
Sbjct: 1101 GQTALMLATSQCRTDMVELLLETGADCNQQDFDGSTALMCACEHG 1235

 Score = 28.5 bits (62), Expect = 8.3,   Method: Compositional matrix adjust.
 Identities = 32/135 (23%), Positives = 63/135 (46%), Gaps = 8/135 (5%)
 Frame = +3

Query: 146 NVQEVRRL---LSEGADVNARHKLGWTALMVASISHNESVVQVLLAAGADPNLGDEFSSV 202
           N++E   L   + +  +V A + +  T +    ++ N+SVVQ            +E+  V
Sbjct: 633 NIRETYELSDDMRKACEVLANYLVDSTTIQTKELNXNQSVVQ------------EEWFRV 776

Query: 203 YKTANEQGVHSLEVLVTREDDFNNRL----NHRASFKGCTALHYAVLADDYSIVKELLDR 258
             +     +H +E  ++  ++ ++RL     +     G +A+HY V   ++ IV  LLD 
Sbjct: 777 -SSHKLSSMHQVEDYLSSINEISHRLLEYIVNLVDSNGNSAIHYCVSHCNFDIVGLLLDT 953

Query: 259 GANPLQR-NEMGHTP 272
               ++R N+ G+TP
Sbjct: 954 EVCDVKRPNKAGYTP 998
>12417
          Length = 954

 Score = 33.9 bits (76), Expect = 0.20,   Method: Compositional matrix adjust.
 Identities = 23/73 (31%), Positives = 36/73 (49%)
 Frame = +2

Query: 137 ALMEAARANNVQEVRRLLSEGADVNARHKLGWTALMVASISHNESVVQVLLAAGADPNLG 196
           AL  AA     +   +L+  GADVN+  + G T L  AS   +  +V +LL  GAD +  
Sbjct: 242 ALAMAANRGLDKMCSQLIQTGADVNSATEHGRTPLHXASAQGHGHIVDLLLEKGADIDAE 421

Query: 197 DEFSSVYKTANEQ 209
           D++     +  +Q
Sbjct: 422 DDYGDTALSIADQ 460
>09292
          Length = 1486

 Score = 33.1 bits (74), Expect = 0.38,   Method: Compositional matrix adjust.
 Identities = 22/67 (32%), Positives = 35/67 (52%)
 Frame = -2

Query: 132  SNKDAALMEAARANNVQEVRRLLSEGADVNARHKLGWTALMVASISHNESVVQVLLAAGA 191
            S+ + AL       +V+    LL   ADVNAR+ +  T L + +I  +  +V+ L+  GA
Sbjct: 1368 SHHETALHAVCYVGSVKMASVLLKHXADVNARNNVDRTPLHIXAIEGHLGLVEELVRHGA 1189

Query: 192  DPNLGDE 198
            D N  D+
Sbjct: 1188 DFNAEDK 1168
>19166
          Length = 447

 Score = 32.7 bits (73), Expect = 0.47,   Method: Compositional matrix adjust.
 Identities = 35/136 (25%), Positives = 62/136 (45%), Gaps = 2/136 (1%)
 Frame = +1

Query: 148 QEVRRLLSEGADVNARHKLGWTALMVASISHNESVVQVLLAAGADPNLGDEFS-SVYKTA 206
           +  + LL    + N+R   G+T L +A   +   VV++LL  GA  +   E   +    +
Sbjct: 1   KTAKLLLDRKCEPNSRALNGFTPLHIACKKNRIKVVELLLKYGASIDATTESGLTPLHVS 180

Query: 207 NEQGVHSLEVLVTREDDFNNRLNHRASFKGCTALHYAVLADDYSIVKELLDRGANPLQRN 266
           +  G  ++ + + + + + +      + +G T+LH A  A+   I++ LL  GA    R 
Sbjct: 181 SFMGHMNIVIYLIQHNAYPDT----PTVRGETSLHLAARANQTDIIRILLRNGAAVDARA 348

Query: 267 EMGHTPLDYA-REGEV 281
               TPL  A R G V
Sbjct: 349 REQQTPLHIASRLGNV 396
>11861
          Length = 586

 Score = 32.3 bits (72), Expect = 0.64,   Method: Compositional matrix adjust.
 Identities = 21/61 (34%), Positives = 31/61 (50%)
 Frame = -1

Query: 213 SLEVLVTREDDFNNRLNHRASFKGCTALHYAVLADDYSIVKELLDRGANPLQRNEMGHTP 272
           +++ L+T +D   N+  HR     C ALH A     + IV   L  GA+  + +E G TP
Sbjct: 535 AIKPLLTEKDSMGNQ--HR-----CIALHEAAKRHQWDIVDHCLTHGADINKVDEQGFTP 377

Query: 273 L 273
           L
Sbjct: 376 L 374

 Score = 30.8 bits (68), Expect = 1.8,   Method: Compositional matrix adjust.
 Identities = 36/159 (22%), Positives = 59/159 (37%)
 Frame = -1

Query: 115 MWALAMALVVQCYSKNPSNKDAALMEAARANNVQEVRRLLSEGADVNARHKLGWTALMVA 174
           +W     L+ +  S    ++  AL EAA+ +    V   L+ GAD+N   + G+T L   
Sbjct: 544 IWPAIKPLLTEKDSMGNQHRCIALHEAAKRHQWDIVDHCLTHGADINKVDEQGFTPL--- 374

Query: 175 SISHNESVVQVLLAAGADPNLGDEFSSVYKTANEQGVHSLEVLVTREDDFNNRLNHRASF 234
                                   F   YK  +   V   E+L+   D      + +   
Sbjct: 373 ------------------------FRVAYKDVHPDWVAVKELLIRGADASATESSRKPLV 266

Query: 235 KGCTALHYAVLADDYSIVKELLDRGANPLQRNEMGHTPL 273
           K       AV    + +VK L+   A+  + ++MG TPL
Sbjct: 265 K------LAVRKKQWDVVKALILNHADIYRPDKMGQTPL 167
>22305
          Length = 426

 Score = 32.3 bits (72), Expect = 0.64,   Method: Composition-based stats.
 Identities = 23/70 (32%), Positives = 29/70 (41%)
 Frame = -3

Query: 126 CYSKNPSNKDAALMEAARANNVQEVRRLLSEGADVNARHKLGWTALMVASISHNESVVQV 185
           CY+++ S          R N       LL  G   N R+  G   L  A    N  V +V
Sbjct: 382 CYTQSVS---------VRVNAADITTALLERGCSANERNHWGILPLHEALCWENVEVGRV 230

Query: 186 LLAAGADPNL 195
           LL  GADPN+
Sbjct: 229 LLQYGADPNV 200
>09214
          Length = 2116

 Score = 32.0 bits (71), Expect = 0.75,   Method: Compositional matrix adjust.
 Identities = 22/61 (36%), Positives = 34/61 (55%), Gaps = 2/61 (3%)
 Frame = -3

Query: 156  EGADVNARHKL-GWTALMVASISHNESVVQVLLAAGADPNLGDEFSSVY-KTANEQGVHS 213
            +  DVNA++K+ G TAL   +   +++VVQ LL+ GAD N  D    +  +      VH+
Sbjct: 1646 KNVDVNAQNKMNGRTALHWGAKRDHQTVVQYLLSHGADKNAVDNDGKIAGQLTTNSDVHT 1467

Query: 214  L 214
            L
Sbjct: 1466 L 1464
>33144
          Length = 272

 Score = 32.0 bits (71), Expect = 0.80,   Method: Compositional matrix adjust.
 Identities = 17/40 (42%), Positives = 24/40 (60%)
 Frame = +3

Query: 238 TALHYAVLADDYSIVKELLDRGANPLQRNEMGHTPLDYAR 277
           T LHYAV   + +I+  LL R ANP  ++  G+TP   A+
Sbjct: 120 TPLHYAVQTCELTIIDLLLGRDANPNIQDVDGNTPTHLAQ 239
>02564
          Length = 1425

 Score = 31.6 bits (70), Expect = 0.96,   Method: Compositional matrix adjust.
 Identities = 31/109 (28%), Positives = 45/109 (41%), Gaps = 17/109 (15%)
 Frame = +1

Query: 174 ASISHNESVVQVLLAAGADPNLGDEFSSV--YKTAN----------EQGVHSLEVL--VT 219
           ASI    S  Q     G+ PN+G   S++  YK +           E+G H +E +  + 
Sbjct: 247 ASIPQGPSTQQAFARRGSKPNIGRRMSTILRYKMSRNQPAVPEDEFEEGNH-MEPIREMP 423

Query: 220 REDDFNNRLNHRASF---KGCTALHYAVLADDYSIVKELLDRGANPLQR 265
           +   F+  L+  A F   KG     Y  +AD     K  L R   PLQ+
Sbjct: 424 QSPRFSTYLSPEAQFAMLKGYEDKLYEKIADTNPEFKASLQRTKTPLQK 570
>28691
          Length = 562

 Score = 31.6 bits (70), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 29/84 (34%), Positives = 44/84 (52%), Gaps = 6/84 (7%)
 Frame = +1

Query: 137 ALMEAARANNVQEVRRLLSEGADVNARHKL---GWTAL--MVASISHNESVVQVLLAAGA 191
           AL  AA+  +V  +  L+  GADVNA+      G TAL   V+  + N   V  LL+ GA
Sbjct: 127 ALHLAAKNKHVDCIPVLVQAGADVNAKGPSTIKGNTALHEAVSVGASNVDSVDALLSCGA 306

Query: 192 DPNLGDEFS-SVYKTANEQGVHSL 214
           D N+ +E   + Y  A++ G  ++
Sbjct: 307 DQNIXNEKGETAYDLASKAGYENI 378

 Score = 31.2 bits (69), Expect = 1.4,   Method: Compositional matrix adjust.
 Identities = 27/66 (40%), Positives = 37/66 (56%), Gaps = 4/66 (6%)
 Frame = +1

Query: 128 SKNPSN--KDAALMEAAR--ANNVQEVRRLLSEGADVNARHKLGWTALMVASISHNESVV 183
           +K PS    + AL EA    A+NV  V  LLS GAD N  ++ G TA  +AS +  E++V
Sbjct: 202 AKGPSTIKGNTALHEAVSVGASNVDSVDALLSCGADQNIXNEKGETAYDLASKAGYENIV 381

Query: 184 QVLLAA 189
           +   AA
Sbjct: 382 KRFAAA 399
>27434
          Length = 472

 Score = 31.6 bits (70), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 27/107 (25%), Positives = 47/107 (43%), Gaps = 10/107 (9%)
 Frame = +2

Query: 346 VFLFLGSSGIGKTELAKQTAKYMHKDAKKGFIRLDMSEFQERHEV----AKFIGSPPGYI 401
           +  F+G  G+GKT + +  A  + ++    F R+ +    ++ ++      +IGS PG I
Sbjct: 167 ILCFVGPPGVGKTSIGRSIATTLGRE----FHRIALGGVCDQSDIRGHRRTYIGSMPGRI 334

Query: 402 --GHEEGGQLTKKLKQCPNAVVLFDEVDK----AHPDVLTIMLQLFD 442
             G +  G          N V   DE+DK     H D    +L++ D
Sbjct: 335 IQGLKSAGT--------NNPVFPLDEIDKLSTSLHGDPAAALLEVLD 451
>00540
          Length = 3034

 Score = 31.2 bits (69), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 20/50 (40%), Positives = 28/50 (56%), Gaps = 2/50 (4%)
 Frame = -2

Query: 151  RRLLSEGADVNARHKLGWTALMVASISHN--ESVVQVLLAAGADPNLGDE 198
            R L+  GAD NAR   G  AL  AS+      +VV+ LLA GA  ++ ++
Sbjct: 1755 RILIKVGADTNARDSQGNVALHFASMGKKVRMAVVEALLAGGAHADVCNK 1606
>22269
          Length = 1060

 Score = 30.8 bits (68), Expect = 1.8,   Method: Compositional matrix adjust.
 Identities = 22/79 (27%), Positives = 36/79 (45%)
 Frame = +2

Query: 134 KDAALMEAARANNVQEVRRLLSEGADVNARHKLGWTALMVASISHNESVVQVLLAAGADP 193
           +D ++    + NNV+  R L+  GAD NA  + G + L +A+ +     V +LL      
Sbjct: 305 EDNSITLGCQKNNVECARILICHGADYNATDENGESPLFMAAAAGLPDSVMMLLKQA--- 475

Query: 194 NLGDEFSSVYKTANEQGVH 212
            LG    S+    N   +H
Sbjct: 476 -LGFPILSIPSKENSTALH 529
>02114
          Length = 1072

 Score = 30.4 bits (67), Expect = 2.5,   Method: Compositional matrix adjust.
 Identities = 16/42 (38%), Positives = 24/42 (57%)
 Frame = +1

Query: 150 VRRLLSEGADVNARHKLGWTALMVASISHNESVVQVLLAAGA 191
           V+ LL  G DVN+  K  WT++ V+S       +Q+L+  GA
Sbjct: 349 VQTLLRCGVDVNSVDKTSWTSVHVSSYHGRLGCLQMLIKWGA 474
>09180
          Length = 610

 Score = 30.4 bits (67), Expect = 2.6,   Method: Compositional matrix adjust.
 Identities = 36/136 (26%), Positives = 53/136 (38%)
 Frame = +3

Query: 151 RRLLSEGADVNARHKLGWTALMVASISHNESVVQVLLAAGADPNLGDEFSSVYKTANEQG 210
           R L ++  + NA  K G TAL V++     +V+ VLL AG D N  D             
Sbjct: 117 RWLQNKNIEDNAHPKTGATALHVSAAKGYINVMNVLLQAGVDINAQD------------- 257

Query: 211 VHSLEVLVTREDDFNNRLNHRASFKGCTALHYAVLADDYSIVKELLDRGANPLQRNEMGH 270
                                    G T+LH AV        + L+D   +   +N  GH
Sbjct: 258 -----------------------ADGWTSLHAAVHWGQEDSCQVLVDHFCDMDVKNNAGH 368

Query: 271 TPLDYAREGEVMKLLK 286
           T  D A + E++K+L+
Sbjct: 369 TVFDLA-DKEMLKVLE 413

 Score = 30.0 bits (66), Expect = 2.8,   Method: Compositional matrix adjust.
 Identities = 24/77 (31%), Positives = 39/77 (50%), Gaps = 1/77 (1%)
 Frame = +3

Query: 146 NVQEVRRLLSEGADVNARHKLGWTALMVASISHNESVVQVLLAAGADPNLGDEFS-SVYK 204
           NV  V  LL  G D+NA+   GWT+L  A     E   QVL+    D ++ +    +V+ 
Sbjct: 207 NVMNV--LLQAGVDINAQDADGWTSLHAAVHWGQEDSCQVLVDHFCDMDVKNNAGHTVFD 380

Query: 205 TANEQGVHSLEVLVTRE 221
            A+++ +  LE L  ++
Sbjct: 381 LADKEMLKVLEELKKKQ 431
>06853
          Length = 2369

 Score = 30.4 bits (67), Expect = 2.6,   Method: Compositional matrix adjust.
 Identities = 20/61 (32%), Positives = 30/61 (49%)
 Frame = +2

Query: 162 ARHKLGWTALMVASISHNESVVQVLLAAGADPNLGDEFSSVYKTANEQGVHSLEVLVTRE 221
           +RH  G   ++      NE V +V     +DP+  D F SV  TAN++GV    V ++  
Sbjct: 458 SRHP-GSKVILCTDGKSNEGVGKVENLQDSDPSPDDFFDSVASTANDKGVSVSVVTISGT 634

Query: 222 D 222
           D
Sbjct: 635 D 637
>05396
          Length = 1865

 Score = 29.3 bits (64), Expect = 5.4,   Method: Compositional matrix adjust.
 Identities = 22/57 (38%), Positives = 29/57 (50%), Gaps = 4/57 (7%)
 Frame = +3

Query: 234  FKGCTALHYAVLADDYSIVKELLDRG-ANPLQRNEMGHTPLDYA---REGEVMKLLK 286
            + G TALH A       +V+ LLDR   +P   +  G TPLD A    + E  +LLK
Sbjct: 1377 YDGRTALHVASAEGQLQVVEFLLDRCKCSPFLVDRWGFTPLDDAVRFEKHEAAELLK 1547
>15772
          Length = 1282

 Score = 29.3 bits (64), Expect = 5.7,   Method: Compositional matrix adjust.
 Identities = 17/49 (34%), Positives = 23/49 (46%)
 Frame = -3

Query: 238  TALHYAVLADDYSIVKELLDRGANPLQRNEMGHTPLDYAREGEVMKLLK 286
            TALH+A        ++ LLD GA    R + G TP   A E   +  L+
Sbjct: 1172 TALHWACQKGFVECIRLLLDHGAKGTARTDTGWTPAHCAAECNRVTALR 1026
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|83627717|ref|NP_031943.3| eukaryotic translation
initiation factor 4E [Mus musculus]
         (217 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

04602                                                                  49   1e-06
01293                                                                  44   5e-05
09541                                                                  31   0.31 
10361                                                                  27   4.6  
13481                                                                  27   8.1  
>04602
          Length = 888

 Score = 49.3 bits (116), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 23/70 (32%), Positives = 40/70 (57%)
 Frame = +3

Query: 134 LLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENRDAVTHIGRVYKERLGLPPKI 193
           +L ++GE F    +++CGAVV+VR + D +A+W     ++   T I    K  L LP   
Sbjct: 9   ILAMLGEQFM-VGEEICGAVVSVRFQDDILALWNRTASDQATTTRIRDTLKRVLHLPANT 185

Query: 194 VIGYQSHADT 203
           ++ Y++H D+
Sbjct: 186 IMEYKTHNDS 215
>01293
          Length = 1593

 Score = 43.9 bits (102), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 21/66 (31%), Positives = 37/66 (56%)
 Frame = +3

Query: 134 LLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENRDAVTHIGRVYKERLGLPPKI 193
           +L ++GE F    +++CGAVV+VR + D +A+W     ++   T I    K  L LP   
Sbjct: 9   ILAMLGEQFM-VGEEICGAVVSVRFQDDILALWNRTASDQATTTRIRDTLKRVLHLPANT 185

Query: 194 VIGYQS 199
           ++ Y++
Sbjct: 186 IMEYKN 203
>09541
          Length = 2010

 Score = 31.2 bits (69), Expect = 0.31,   Method: Compositional matrix adjust.
 Identities = 11/30 (36%), Positives = 19/30 (63%)
 Frame = -1

Query: 81  LSSNLMPGCDYSLFKDGIEPMWEDEKNKRG 110
           + + LM  C Y +F+D I+ MW+  K ++G
Sbjct: 396 IFTELMKNCQYGIFRDEIQKMWKWRKKRQG 307
>10361
          Length = 582

 Score = 27.3 bits (59), Expect = 4.6,   Method: Compositional matrix adjust.
 Identities = 16/42 (38%), Positives = 21/42 (50%), Gaps = 5/42 (11%)
 Frame = -3

Query: 161 DKIAIWTTECENRDAVTHI-----GRVYKERLGLPPKIVIGY 197
           DK  IWT    NRD  TH+       +YK R     K+V+G+
Sbjct: 403 DKSKIWTQGAGNRDIFTHLVGLRGNALYKLRGK*CQKVVLGF 278
>13481
          Length = 528

 Score = 26.6 bits (57), Expect = 8.1,   Method: Compositional matrix adjust.
 Identities = 16/40 (40%), Positives = 20/40 (50%)
 Frame = +2

Query: 160 GDKIAIWTTECENRDAVTHIGRVYKERLGLPPKIVIGYQS 199
           GDKI I    CEN       GR  K RL +   + +G+QS
Sbjct: 347 GDKIVIGV*VCENSHIGNWSGRAKKRRL-VKNSLTVGHQS 463
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|84662774|ref|NP_001033790.1| gamma-aminobutyric acid
(GABA) A receptor, beta 3 isoform b [Mus musculus]
         (473 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

20355                                                                  51   1e-06
37147                                                                  28   6.2  
>20355
          Length = 425

 Score = 50.8 bits (120), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 29/111 (26%), Positives = 61/111 (54%)
 Frame = -2

Query: 161 CMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGDKAVTGVERIELPQFSIVEHRLVS 220
           C +D+  YPLD Q CTLE+ S+ Y   D+  +       ++ VE    P++++   R ++
Sbjct: 388 CSIDITSYPLDTQECTLEVMSWVYARHDVRTHVSKPAFDMSMVE--SHPEWTL--SRTLA 221

Query: 221 RNVVFATGAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINYDA 271
           R VV  +  +  L  +  L+R + +F++   +P I++++++ + F +  D+
Sbjct: 220 R-VVRKSNNFDVLRFTLVLRRKVIFFVVNLILPIIMLSLMNCLVFLLPVDS 71
>37147
          Length = 693

 Score = 28.5 bits (62), Expect = 6.2,   Method: Compositional matrix adjust.
 Identities = 16/59 (27%), Positives = 26/59 (44%), Gaps = 18/59 (30%)
 Frame = -3

Query: 432 SSQLKIKIPDLTDVNAIDRWSRIVFPFTF------------------SLFNLVYWLYYV 472
           SS   + +    DV +++ WS  +FPF F                    ++LV+WLY+V
Sbjct: 493 SSAESVCLEVCLDVFSLETWSNCLFPFLFGFLVSCLVFB*WVIFSADCFWDLVFWLYFV 317
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|9055336|ref|NP_061241.1| GIPC PDZ domain containing
family, member 1 [Mus musculus]
         (333 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

33626                                                                  50   1e-06
17774                                                                  32   0.39 
20073                                                                  31   0.72 
26458                                                                  30   2.0  
>33626
          Length = 391

 Score = 50.1 bits (118), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 22/29 (75%), Positives = 23/29 (79%)
 Frame = +1

Query: 59  VFHTQLAHGSPTGRIEGFTNVKELYGKIA 87
           VFH Q AHGSPTG I GFTNVK LY K+A
Sbjct: 304 VFHCQQAHGSPTGIISGFTNVKRLYQKVA 390
>17774
          Length = 493

 Score = 32.0 bits (71), Expect = 0.39,   Method: Compositional matrix adjust.
 Identities = 19/54 (35%), Positives = 28/54 (51%)
 Frame = +1

Query: 161 KEGSVIDHIQLISVGDMIEAINGQSLLGCRHYEVARLLKELPRGRTFTLKLTEP 214
           ++   ID +Q I  GD+ + INGQ   GC H   +R  + LP     +L+L  P
Sbjct: 25  RDSETIDLLQAICGGDLTDVINGQRWHGCLHRVDSR-HRNLP----VSLQLDSP 171
>20073
          Length = 582

 Score = 30.8 bits (68), Expect = 0.72,   Method: Compositional matrix adjust.
 Identities = 16/44 (36%), Positives = 24/44 (54%)
 Frame = +3

Query: 156 FIKRIKEGSVIDHIQLISVGDMIEAINGQSLLGCRHYEVARLLK 199
           +I RI  G V D +  +  GD + ++NG S+ G  H +   LLK
Sbjct: 51  YISRIIPGGVADRLNCLKRGDQLLSVNGVSVEGEYHEKAVELLK 182
>26458
          Length = 873

 Score = 29.6 bits (65), Expect = 2.0,   Method: Compositional matrix adjust.
 Identities = 16/56 (28%), Positives = 25/56 (44%)
 Frame = -2

Query: 61  HTQLAHGSPTGRIEGFTNVKELYGKIAEAFRLPAAEVMFCTLNTHKVDMDKLLGGQ 116
           H QL     +GR+    +V      +  AFR  AA   +  +N   +D+  + GGQ
Sbjct: 587 HNQLLLFLASGRLARLFDVLRFLQVVGGAFRFTAAPCFYLDINRFGLDVLHVFGGQ 420
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|19882207|ref|NP_608219.1| farnesyl diphosphate
synthetase [Mus musculus]
         (353 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

29064                                                                  47   2e-06
17346                                                                  31   0.60 
25620                                                                  31   0.72 
09295                                                                  29   3.5  
13613                                                                  28   5.4  
06408                                                                  28   7.7  
>29064
          Length = 375

 Score = 46.6 bits (109), Expect(2) = 2e-06,   Method: Compositional matrix adjust.
 Identities = 33/87 (37%), Positives = 45/87 (51%), Gaps = 5/87 (5%)
 Frame = +1

Query: 18  IQHFSQIVKVLTEKELGHPEI--GDAIARL---KEVLEYNALGGKYNRGLTVVQAFQELV 72
           +Q F  I + L    L  P +   D IA +   +E   YN   GK NRG++VV + + L 
Sbjct: 91  LQQFDDIFEELLADVLTCPAVQGRDTIAAVEWFREASRYNVPHGKKNRGISVVSSLRVL- 267

Query: 73  EPKKQDAESLQRALTVGWCVELLQAFF 99
           +    DA+ L  A  +GWCVE LQA F
Sbjct: 268 KKDYTDAD-LNTARVLGWCVEWLQAIF 345

 Score = 22.7 bits (47), Expect(2) = 2e-06,   Method: Compositional matrix adjust.
 Identities = 8/11 (72%), Positives = 11/11 (100%)
 Frame = +3

Query: 98  FFLVSDDIMDS 108
           FFLV+DD+MD+
Sbjct: 342 FFLVADDVMDA 374
>17346
          Length = 980

 Score = 31.2 bits (69), Expect = 0.60,   Method: Compositional matrix adjust.
 Identities = 13/36 (36%), Positives = 19/36 (52%)
 Frame = -1

Query: 107 DSSLTRRGQICWYQKPGIGLDAINDALLLEASIYRL 142
           D +LTR   +CW   PG  +  +    L+ AS +RL
Sbjct: 620 DRALTRTSSVCWLTAPGXNMSGM--VALVTASTHRL 519
>25620
          Length = 850

 Score = 31.2 bits (69), Expect = 0.72,   Method: Compositional matrix adjust.
 Identities = 31/123 (25%), Positives = 50/123 (40%), Gaps = 1/123 (0%)
 Frame = -1

Query: 17  FIQHFSQIVKVLTEKELGHPEIG-DAIARLKEVLEYNALGGKYNRGLTVVQAFQELVEPK 75
           F  HF+  + V++  +L  P +   A+ R  E  E N  GGK           Q+L E +
Sbjct: 472 FKDHFTNRM-VMSHVQLVLPNLSCRALWRAVENEEVNENGGKTTSXSGPACRLQDLKERQ 296

Query: 76  KQDAESLQRALTVGWCVELLQAFFLVSDDIMDSSLTRRGQICWYQKPGIGLDAINDALLL 135
           + +   ++ +    WC + L A  L  DD + S     G  C  +   I  + I    + 
Sbjct: 295 RTE*NGVKLSKDHQWCPDGLAAMGLDDDDDIQSGTQNTGHFCPTKSLQIFHNCIKSGYIR 116

Query: 136 EAS 138
           E S
Sbjct: 115 EPS 107
>09295
          Length = 1434

 Score = 28.9 bits (63), Expect = 3.5,   Method: Compositional matrix adjust.
 Identities = 18/53 (33%), Positives = 25/53 (47%), Gaps = 7/53 (13%)
 Frame = -1

Query: 251  DPSVTGKVGTDIQDNKCSWLVVQCLLRAS-------PQQRQILEENYGQKDPE 296
            DP   G+V   +  N  S LVV C + A        P  + ILE ++ Q+D E
Sbjct: 1212 DPGGXGQVFRSVAVNILSALVVDCEMAADRRLGKVLPHLKSILETSFAQEDKE 1054
>13613
          Length = 577

 Score = 28.1 bits (61), Expect = 5.4,   Method: Compositional matrix adjust.
 Identities = 21/80 (26%), Positives = 35/80 (43%), Gaps = 12/80 (15%)
 Frame = -1

Query: 241 VQDDYLDLF-GDPSVTGKV-----------GTDIQDNKCSWLVVQCLLRASPQQRQILEE 288
           V  D  DL  G  SV GK+           G  ++++K  WLV+   +R    + Q  + 
Sbjct: 310 VLHDSFDLMEGRKSVGGKLEVKVRVRDPFKGRQVEESKEKWLVIDQFIRTMGSKSQAGQA 131

Query: 289 NYGQKDPEKVARVKALYEAL 308
           +     P+K + V +L + L
Sbjct: 130 SAASSKPKKESSVMSLLDKL 71
>06408
          Length = 1830

 Score = 27.7 bits (60), Expect = 7.7,   Method: Compositional matrix adjust.
 Identities = 13/39 (33%), Positives = 17/39 (43%), Gaps = 4/39 (10%)
 Frame = -3

Query: 2    NGNQKLDAYNQEKQNFI----QHFSQIVKVLTEKELGHP 36
            N NQ+    +Q   N +     HF QI   LT   + HP
Sbjct: 1693 NNNQRKSNSSQSSFNLVCTLVSHFXQITSTLTTMTMNHP 1577
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|21313026|ref|NP_080349.1| RAB, member of RAS oncogene
family-like 5 [Mus musculus]
         (185 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

08428                                                                  48   2e-06
26083                                                                  44   4e-05
13901                                                                  39   0.001
05468                                                                  38   0.002
33605                                                                  36   0.007
11257                                                                  35   0.019
14456                                                                  34   0.027
33374                                                                  34   0.034
10862                                                                  31   0.27 
11378                                                                  31   0.33 
31794                                                                  31   0.35 
19656                                                                  30   0.41 
21324                                                                  30   0.71 
13750                                                                  29   0.92 
14775                                                                  29   1.4  
19118                                                                  27   4.0  
04006                                                                  27   4.3  
20382                                                                  27   5.5  
28292                                                                  27   6.3  
27191                                                                  26   8.7  
>08428
          Length = 1109

 Score = 48.1 bits (113), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 29/104 (27%), Positives = 47/104 (45%), Gaps = 2/104 (1%)
 Frame = -3

Query: 1    MLKAKILFVGPCESGKT-VLANFLTESSDITEYNPTQGVRI-LEFENPHVTSNNKGTGCE 58
            M   K+  +G    GK+ ++  F+T S     Y P+Q   I   F +  +  +  G G  
Sbjct: 1077 MRDVKVCLLGDSGVGKSSIVLRFVTGS-----YRPSQESTIGASFMSKSLVVD--GAGYR 919

Query: 59   FELWDCGGDSKFESCWPALMKDAHGVVIVFNADIPSHLKEIEMW 102
            F++WD  G  KF +  P   + A   VIV++   P   K ++ W
Sbjct: 918  FQIWDTAGQEKFRALAPMYYRGAAAAVIVYDVTRPRTFKSVKSW 787
>26083
          Length = 432

 Score = 43.9 bits (102), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 27/103 (26%), Positives = 48/103 (46%), Gaps = 1/103 (0%)
 Frame = +1

Query: 1   MLKAKILFVGPCESGKT-VLANFLTESSDITEYNPTQGVRILEFENPHVTSNNKGTGCEF 59
           + K K++F+G    GKT ++  F+ +S D T Y  T G+  L       T   +      
Sbjct: 70  LRKFKLVFLGEQSVGKTSLITRFMYDSFDNT-YQATIGIDFLS-----KTMYLEDRTIRL 231

Query: 60  ELWDCGGDSKFESCWPALMKDAHGVVIVFNADIPSHLKEIEMW 102
           +LWD  G  +F S  P+ ++D+   V+V++    +   +   W
Sbjct: 232 QLWDTAGQERFRSLIPSYIRDSSVAVVVYDITNANSFHQTSKW 360
>13901
          Length = 962

 Score = 38.5 bits (88), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 23/85 (27%), Positives = 38/85 (44%)
 Frame = -3

Query: 5   KILFVGPCESGKTVLANFLTESSDITEYNPTQGVRILEFENPHVTSNNKGTGCEFELWDC 64
           K++ +G    GKT         S   +Y  T GV   +F    +  ++K    + +LWD 
Sbjct: 282 KVIIIGDPTVGKTSFVQRYVNDSFRRDYKMTIGV---DFALKVIRWSDK-CNIKLQLWDI 115

Query: 65  GGDSKFESCWPALMKDAHGVVIVFN 89
            G  +F S      KDAH  +++F+
Sbjct: 114 AGQERFTSMTRVYYKDAHACIVMFD 40
>05468
          Length = 1558

 Score = 37.7 bits (86), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 30/121 (24%), Positives = 47/121 (38%), Gaps = 3/121 (2%)
 Frame = -3

Query: 5    KILFVGPCESGKTVLANFLTESSDITEYNPTQGVRILEFENPHVTSNNKGTGCEFELWDC 64
            KIL +G   +GKT +            Y  T GV         V + +  T    +LWD 
Sbjct: 1535 KILVIGELGTGKTSIIKRYVHQFFSQHYRATIGVDFA----LKVLNWDADTLIRLQLWDI 1368

Query: 65   GGDSKFESCWPALMKDAHGVVIVFNADIPSHLKEIEMWYSCFVQQQFLQDSH---CMLVA 121
             G  +F +      K+A G  +VF+    S    +  W +    +  L D     C+L+A
Sbjct: 1367 AGQERFGNMTRVYYKEAVGAFVVFDVTRASTFDAVTKWKNDLDSKVQLADGSPVPCVLLA 1188

Query: 122  H 122
            +
Sbjct: 1187 N 1185
>33605
          Length = 888

 Score = 36.2 bits (82), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 24/88 (27%), Positives = 37/88 (42%), Gaps = 1/88 (1%)
 Frame = +1

Query: 4   AKILFVGPCESGKT-VLANFLTESSDITEYNPTQGVRILEFENPHVTSNNKGTGCEFELW 62
            ++L +G   +GKT +L  F     DI   +PT G  I   E+          G +  +W
Sbjct: 499 VRLLMLGLDNAGKTTILKKF--NGEDIDTISPTLGFNIKTLEHR---------GFKLNVW 645

Query: 63  DCGGDSKFESCWPALMKDAHGVVIVFNA 90
           D GG     S W    +   G+V V ++
Sbjct: 646 DVGGQQSLRSYWRNYFESTDGLVWVVDS 729
>11257
          Length = 1102

 Score = 35.0 bits (79), Expect = 0.019,   Method: Compositional matrix adjust.
 Identities = 17/70 (24%), Positives = 29/70 (41%)
 Frame = -2

Query: 46   PHVTSNNKGTGCEFELWDCGGDSKFESCWPALMKDAHGVVIVFNADIPSHLKEIEMWYSC 105
            PH      G     ++WD  G  +++S      +     ++ F+ D    L+ +  WY  
Sbjct: 1059 PHKDVVVDGETFTMQIWDTAGQERYKSLRTPFYRGTDCCLLTFSVDNLKSLQSLSDWYDE 880

Query: 106  FVQQQFLQDS 115
            FV    +QDS
Sbjct: 879  FVNYADIQDS 850
>14456
          Length = 1867

 Score = 34.3 bits (77), Expect = 0.027,   Method: Compositional matrix adjust.
 Identities = 26/101 (25%), Positives = 46/101 (45%), Gaps = 1/101 (0%)
 Frame = -1

Query: 15   GKTVLAN-FLTESSDITEYNPTQGVRILEFENPHVTSNNKGTGCEFELWDCGGDSKFESC 73
            GK+ L N F++   D   ++ T GV   EF N  V  +++      ++WD  G  +F+S 
Sbjct: 1105 GKSSLMNRFVSNKFDAQSFH-TIGV---EFLNKDVVVDDETY--TMQIWDTAGQERFKSL 944

Query: 74   WPALMKDAHGVVIVFNADIPSHLKEIEMWYSCFVQQQFLQD 114
                 + A   ++ F+ D     + + MW   F+    +QD
Sbjct: 943  RTPFYRGADCCLLTFSVDSMQSFRNLSMWRKEFLYYADIQD 821
>33374
          Length = 489

 Score = 34.3 bits (77), Expect = 0.034,   Method: Compositional matrix adjust.
 Identities = 10/35 (28%), Positives = 19/35 (54%)
 Frame = +1

Query: 55  TGCEFELWDCGGDSKFESCWPALMKDAHGVVIVFN 89
           T  +FE+WD  G  ++ S  P   + A   ++V++
Sbjct: 169 TTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYD 273
>10862
          Length = 2896

 Score = 31.2 bits (69), Expect = 0.27,   Method: Compositional matrix adjust.
 Identities = 13/68 (19%), Positives = 28/68 (41%)
 Frame = -3

Query: 57   CEFELWDCGGDSKFESCWPALMKDAHGVVIVFNADIPSHLKEIEMWYSCFVQQQFLQDSH 116
            C+F +WD GG  K    W        G++ V +      + E        +  + ++D+ 
Sbjct: 2486 CQFNVWDVGGQDKIRPLWRHYYTGTQGLIFVVDCADRDRIDEARQELHRIINDREMRDAI 2307

Query: 117  CMLVAHHK 124
             ++ A+ +
Sbjct: 2306 ILIFANKQ 2283
>11378
          Length = 1688

 Score = 30.8 bits (68), Expect = 0.33,   Method: Compositional matrix adjust.
 Identities = 27/130 (20%), Positives = 52/130 (40%), Gaps = 3/130 (2%)
 Frame = +3

Query: 4   AKILFVGPCESGKTVLANFLTESSDITEYNPTQGVRILEFENPHVTSNNKGT-GCEFELW 62
            K++F+G   +GKT L + L +   + ++ PT           H TS      G  F  +
Sbjct: 324 GKLVFLGLDNAGKTTLLHMLKDDK-MAQHVPTL----------HPTSEELSMGGMRFTTF 470

Query: 63  DCGGDSKFESCWPALMKDAHGVVIVFNADIPSHLKEIEMWYSCFVQQQFLQDSHCMLVAH 122
           D GG  +    W        G+V + +      L E +      +  + + ++  +++ +
Sbjct: 471 DLGGHRQARRVWKDYFPAVDGIVFLVDVHDRERLVEAKAELDSLMTDEQVANAPILVLGN 650

Query: 123 H--KPGSGGE 130
              KPG+  E
Sbjct: 651 KIDKPGAASE 680
>31794
          Length = 281

 Score = 30.8 bits (68), Expect = 0.35,   Method: Compositional matrix adjust.
 Identities = 19/60 (31%), Positives = 29/60 (48%)
 Frame = +1

Query: 63  DCGGDSKFESCWPALMKDAHGVVIVFNADIPSHLKEIEMWYSCFVQQQFLQDSHCMLVAH 122
           DCG D++ ESC  +L  D H          PSHL+++ +    F +Q F       L++H
Sbjct: 1   DCGVDTQGESCIFSLPADIHRY-----QP*PSHLEQVYIQLGVFFRQYFPIKFISFLISH 165
>19656
          Length = 428

 Score = 30.4 bits (67), Expect = 0.41,   Method: Compositional matrix adjust.
 Identities = 31/128 (24%), Positives = 43/128 (33%), Gaps = 1/128 (0%)
 Frame = +3

Query: 1   MLKAKILFVGPCESGKTVLANFLTESSDITEYNPTQGVRILEFENPHVTSNNKGTGCEFE 60
           M   K + VG    GKT L    T ++   EY PT       F+N        G      
Sbjct: 105 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTV------FDNYSANVMVDGRPVNLG 266

Query: 61  LWDCGGDSKFESCWPALMKDAHGVVIVFNADIPSHLKEIEM-WYSCFVQQQFLQDSHCML 119
           LWD  G   ++   P         ++ F+   P+  + I   WY                
Sbjct: 267 LWDTAGQEDYDRLRPLSYPQTDVFLLCFSVASPASFENIRAKWYP--------------E 404

Query: 120 VAHHKPGS 127
           V HH PG+
Sbjct: 405 VNHHCPGT 428
>21324
          Length = 449

 Score = 29.6 bits (65), Expect = 0.71,   Method: Compositional matrix adjust.
 Identities = 15/32 (46%), Positives = 18/32 (56%)
 Frame = +3

Query: 7   LFVGPCESGKTVLANFLTESSDITEYNPTQGV 38
           LF  P    KT L NFLT+    TE+ PT+ V
Sbjct: 105 LFPTP-RGNKTALVNFLTKDRQQTEFQPTRRV 197
>13750
          Length = 503

 Score = 29.3 bits (64), Expect = 0.92,   Method: Compositional matrix adjust.
 Identities = 18/70 (25%), Positives = 27/70 (38%), Gaps = 1/70 (1%)
 Frame = -2

Query: 34  PTQGVRILEFENPHVTSNNKGTGCEFELWDCGGDSKFESCWPALMKDAHGVVIVFNADIP 93
           PT  V   EF        N      + LWD GG   + S W +  + A   ++V++    
Sbjct: 448 PTIAVLCSEFNESRTDPLN----VRYTLWDTGGAETYRSLWVSHFRGAQVALLVYDVTCE 281

Query: 94  -SHLKEIEMW 102
            S L    +W
Sbjct: 280 WSFLTATTVW 251
>14775
          Length = 380

 Score = 28.9 bits (63), Expect = 1.4,   Method: Compositional matrix adjust.
 Identities = 15/56 (26%), Positives = 23/56 (41%)
 Frame = -2

Query: 34  PTQGVRILEFENPHVTSNNKGTGCEFELWDCGGDSKFESCWPALMKDAHGVVIVFN 89
           PT  V   EF        N      + LWD GG   + S W +  + A   ++V++
Sbjct: 325 PTIAVLCSEFNESRTDPLN----VRYTLWDTGGAETYRSLWVSHFRGAQVALLVYD 170
>19118
          Length = 441

 Score = 27.3 bits (59), Expect = 4.0,   Method: Compositional matrix adjust.
 Identities = 12/36 (33%), Positives = 21/36 (58%)
 Frame = -1

Query: 131 RGSLALSPPLNKLKLVHSNLEEDPEEVRVEFIKYLK 166
           R   A SPP+N + + +++  +DP  VR+  I+ L 
Sbjct: 165 RA*AASSPPINLMLVSNTDSSDDPSNVRLVAIQSLA 58
>04006
          Length = 512

 Score = 26.9 bits (58), Expect = 4.3,   Method: Compositional matrix adjust.
 Identities = 10/16 (62%), Positives = 12/16 (75%)
 Frame = -2

Query: 55  TGCEFELWDCGGDSKF 70
           TG  FELW CGG+ +F
Sbjct: 133 TGLLFELWSCGGEGRF 86
>20382
          Length = 449

 Score = 26.9 bits (58), Expect = 5.5,   Method: Compositional matrix adjust.
 Identities = 15/59 (25%), Positives = 25/59 (42%)
 Frame = +3

Query: 97  KEIEMWYSCFVQQQFLQDSHCMLVAHHKPGSGGERGSLALSPPLNKLKLVHSNLEEDPE 155
           +E+ +W+     Q F  + H ML+        G RG    +PP N L  +  +  + P 
Sbjct: 141 RELRLWWQQLRLQVFRVERHLMLLQRFGF*EHGSRGRHRSTPPTNPLCFLPQSPSQHPH 317
>28292
          Length = 1324

 Score = 26.6 bits (57), Expect = 6.3,   Method: Compositional matrix adjust.
 Identities = 9/23 (39%), Positives = 16/23 (69%)
 Frame = -3

Query: 1    MLKAKILFVGPCESGKTVLANFL 23
            + K  ILF+GP  +GK+ + N++
Sbjct: 1112 LAKPMILFLGPWSTGKSTMINYI 1044
>27191
          Length = 443

 Score = 26.2 bits (56), Expect = 8.7,   Method: Compositional matrix adjust.
 Identities = 21/87 (24%), Positives = 33/87 (37%)
 Frame = +1

Query: 16  KTVLANFLTESSDITEYNPTQGVRILEFENPHVTSNNKGTGCEFELWDCGGDSKFESCWP 75
           KT L     ES     Y PT GV   ++     T N  G      +WD  G +++     
Sbjct: 1   KTCLIKHFCESKFNQGYQPTVGV---DYGFKIQTVN--GVDMRVHMWDLSGSNEYLDVRN 165

Query: 76  ALMKDAHGVVIVFNADIPSHLKEIEMW 102
            L   +  + IVF+       + ++ W
Sbjct: 166 ELYTGSDAIFIVFDVSNTPSFEALDSW 246
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|23956156|ref|NP_080224.1| LSM14 homolog A [Mus
musculus]
         (462 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

26576                                                                  50   2e-06
09500                                                                  43   3e-04
>26576
          Length = 448

 Score = 49.7 bits (117), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 37/98 (37%), Positives = 44/98 (44%), Gaps = 5/98 (5%)
 Frame = -2

Query: 1   MSGGTPYIGSKISLISKAEIRYEGILYT----IDTENSTVALAKVRSFGTEXXXXXXXXX 56
           M+ G PY+GSKISLI +     +  L+     +D  +   AL     F            
Sbjct: 405 MNQGIPYLGSKISLIQRLRFVMKASLHH*SQ*VDCCSCESAL-----FWHRGPTNRQASS 241

Query: 57  XXXEVFEYIIFRGSDIKDLTVCEPPKPQCSL-PQDPAI 93
                    IFRGSDIKDL VCE  K QC    QDPAI
Sbjct: 240 SKR*YI*VYIFRGSDIKDLHVCETGKAQCQANVQDPAI 127
>09500
          Length = 1120

 Score = 42.7 bits (99), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 18/36 (50%), Positives = 25/36 (69%), Gaps = 4/36 (11%)
 Frame = +3

Query: 367 SFFDNISC----DDNRERRPTWAEERRLNAETFGIP 398
           SFFDNISC    D ++ ++  W +ER+LN ETFG+ 
Sbjct: 3   SFFDNISCEAAQDRSKNKKNDWRQERKLNTETFGVS 110
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|30794152|ref|NP_076216.1| RIKEN cDNA 3322402L07 [Mus
musculus]
         (195 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

17619                                                                  49   2e-06
>17619
          Length = 448

 Score = 48.5 bits (114), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 42/145 (28%), Positives = 69/145 (47%)
 Frame = +1

Query: 13  PPRLSARTPAEMVLETLMMELAGXXXXXXXXXXXXXSAVRKICTGVDYSWLANTPRPTYD 72
           P +L  R     V ++L+ EL                  +K+ TGVDYSWL       Y 
Sbjct: 13  PSKLPDRDERMAVADSLLAELDFHVQELDRLFQQREREKQKLKTGVDYSWLVTAAPKVYK 192

Query: 73  ISPGERLQLEDVCAKIHPSYCGPAILRFRQLLAEREPEVQEVARLFRSVLQEALEKMKQE 132
           +   ERL+LE++C K+ PS C   +  FR+ +  REP V++V R+ R  + + LE+  + 
Sbjct: 193 VPQLERLELEELCLKLEPSECSRVVSHFREAMV-REPRVEDVTRIMRCCVIQVLEQRPRS 369

Query: 133 EEAHKLTRQWSLRPRGSLSSFKTRA 157
           +       +W  +   S +S K ++
Sbjct: 370 QSVSLGVSEWVAQRATSFASLKLKS 444
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31541787|ref|NP_080965.2| mitochondrial ubiquitin
ligase activator of NFKB 1 [Mus musculus]
         (352 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

33428                                                                  50   2e-06
01467                                                                  48   7e-06
07523                                                                  41   9e-04
16561                                                                  29   2.2  
20109                                                                  29   2.6  
36407                                                                  28   7.5  
>33428
          Length = 402

 Score = 49.7 bits (117), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 22/50 (44%), Positives = 32/50 (64%)
 Frame = +2

Query: 301 ACVVCLSNFKSCVFLECGHVCSCRQCYLALPEPKRCPICRREITRVIPLY 350
            CV+CL+N +  V L+CGH+  C  C   LP+ + CP+CR  I R +P+Y
Sbjct: 62  TCVICLNNPREVVTLDCGHISMCTDCAQMLPQ-RLCPVCREPIERFLPVY 208
>01467
          Length = 1335

 Score = 47.8 bits (112), Expect = 7e-06,   Method: Compositional matrix adjust.
 Identities = 23/52 (44%), Positives = 30/52 (57%)
 Frame = -2

Query: 298  LKSACVVCLSNFKSCVFLECGHVCSCRQCYLALPEPKRCPICRREITRVIPL 349
            + S CVVCL      +FL CGHVC+C  C   L E   CP+CR  I++ + L
Sbjct: 1028 INSECVVCLDRTSEVIFLPCGHVCTCPVCSPPLSE---CPMCRAPISQRVRL 882
>07523
          Length = 1299

 Score = 40.8 bits (94), Expect = 9e-04,   Method: Compositional matrix adjust.
 Identities = 18/49 (36%), Positives = 28/49 (57%), Gaps = 1/49 (2%)
 Frame = -1

Query: 293 EDRESLKSACVVCLSNFKSCVFLECGHVCSCRQCYLALP-EPKRCPICR 340
           E+ E   + CV+C+S+ +  + L C H+C C  C  +L  +   CPICR
Sbjct: 483 EEVEDSGAECVICMSDMRDTLILPCRHLCLCSACAESLRYQASMCPICR 337
>16561
          Length = 2029

 Score = 29.3 bits (64), Expect = 2.2,   Method: Compositional matrix adjust.
 Identities = 16/39 (41%), Positives = 23/39 (58%)
 Frame = -1

Query: 313 VFLECGHVCSCRQCYLALPEPKRCPICRREITRVIPLYN 351
           +  +CGH   C+ C  +L   + CP+CR+ IT  IPLY 
Sbjct: 877 MVFKCGHA-VCKICSESL---QLCPMCRKTITMRIPLYT 773
>20109
          Length = 418

 Score = 29.3 bits (64), Expect = 2.6,   Method: Compositional matrix adjust.
 Identities = 19/49 (38%), Positives = 22/49 (44%), Gaps = 5/49 (10%)
 Frame = -1

Query: 301 ACVVCLSNFKSCVFLECGHVCSCRQCY--LALPEPKR---CPICRREIT 344
            C VC   F+   FL C H   C QC   LA   P     CP+CR  +T
Sbjct: 334 TCTVCFEVFRDPRFLPCHHT-FCLQCLADLASRSPSSTFPCPVCRHHVT 191
>36407
          Length = 1085

 Score = 27.7 bits (60), Expect = 7.5,   Method: Compositional matrix adjust.
 Identities = 21/50 (42%), Positives = 27/50 (54%)
 Frame = -2

Query: 198 IGELVLDNNAVRLQPPKQGMQYYLSSQDFDSLLHRQESSVRLWKILVLVF 247
           +GEL L +    L   K+G Q+ L  + F   LHR E SV+L  IL L F
Sbjct: 163 VGELALVSLCT-LALLKEGTQHRLGIRPFGHCLHRSEQSVKL--ILHLFF 23
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|38049585|ref|XP_283579.2| PREDICTED: hypothetical
protein LOC68115 isoform 1 [Mus musculus]
         (291 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

11600                                                                  49   2e-06
00174                                                                  27   8.0  
>11600
          Length = 1523

 Score = 48.9 bits (115), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 38/144 (26%), Positives = 65/144 (45%), Gaps = 1/144 (0%)
 Frame = -1

Query: 144  FSEGAKQAFAYVSKLLSQCKFDLLEELVAKEVLQILKEKVTSLSDNHKNALAADIDDIVY 203
            F EGA QA   VS L+S+  F+ L+ LV  E L  ++     L    +N L     ++  
Sbjct: 1391 FLEGALQAATCVSNLISEGNFEDLKGLVEDEALPEIQRNYGDLLFQQRNWLKIKPSEVYL 1212

Query: 204  TSTGDISIYYDEK-GRKFVNILMCFWYLTSANIPSESLSGANVFQVKLGDQSVETKQLLS 262
                 I + +D+   R+FV I +    L   +    S+S   +++    +       +  
Sbjct: 1211 KFIYQIGMMFDDNTDRRFVEITVV---LHGCHNTENSVSNLEIYE----NMKEYPHNVYV 1053

Query: 263  ASYEFQREFTQGVKPDWTIARIEH 286
             +Y F RE+T+GV+  W I ++ H
Sbjct: 1052 CNYRFIREYTKGVEDSWIINKLNH 981
>00174
          Length = 1223

 Score = 27.3 bits (59), Expect = 8.0,   Method: Compositional matrix adjust.
 Identities = 13/32 (40%), Positives = 19/32 (59%)
 Frame = -1

Query: 226 CFWYLTSANIPSESLSGANVFQVKLGDQSVET 257
           C W ++   IP +SLS    F+   GD+S+ET
Sbjct: 413 CLWCVSELKIPDQSLS---TFKHTSGDKSLET 327
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|88853581|ref|NP_031994.2| Ewing sarcoma breakpoint
region 1 [Mus musculus]
         (655 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

11758                                                                  50   2e-06
03744                                                                  38   0.013
20488                                                                  38   0.013
16427                                                                  37   0.023
11126                                                                  36   0.055
14258                                                                  34   0.23 
01065                                                                  33   0.49 
25691                                                                  32   0.60 
33516                                                                  32   0.82 
00738                                                                  32   0.86 
08816                                                                  32   0.96 
35180                                                                  31   1.9  
25950                                                                  29   5.0  
14637                                                                  28   8.5  
>11758
          Length = 477

 Score = 50.4 bits (119), Expect = 2e-06,   Method: Composition-based stats.
 Identities = 17/26 (65%), Positives = 18/26 (69%)
 Frame = -3

Query: 520 DWQCPNPGCGNQNFAWRTECNQCKAP 545
           DW C NP CGN NF WR ECN+C  P
Sbjct: 154 DWTCVNPDCGNNNFRWRNECNRCNTP 77
>03744
          Length = 3486

 Score = 38.1 bits (87), Expect = 0.013,   Method: Compositional matrix adjust.
 Identities = 26/90 (28%), Positives = 39/90 (43%)
 Frame = -1

Query: 358  DNSAIYVQGLNDNVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYE 417
            D + +++  L       DL   F   G V   K        +++DK+T   K    VSY+
Sbjct: 3222 DGANLFIYHLPQEFGDQDLMQMFMPFGNVVSAK--------VFIDKQTNLSKCFGFVSYD 3067

Query: 418  DPPTAKAAVEWFDGKDFQGSKLKVSLARKK 447
             P  A+AA+   +G      +LKV L R K
Sbjct: 3066 SPLAAQAAITSMNGFQIGMKRLKVQLKRSK 2977
>20488
          Length = 3281

 Score = 37.7 bits (86), Expect = 0.013,   Method: Compositional matrix adjust.
 Identities = 18/49 (36%), Positives = 27/49 (55%)
 Frame = +2

Query: 399  IYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKK 447
            +++DK+T   K    VSY+ P  A+AA+   +G      +LKV L R K
Sbjct: 2801 VFIDKQTNLSKCFGFVSYDSPLAAQAAITSMNGFQIGMKRLKVQLKRSK 2947
>16427
          Length = 1313

 Score = 37.0 bits (84), Expect = 0.023,   Method: Compositional matrix adjust.
 Identities = 26/83 (31%), Positives = 39/83 (46%)
 Frame = +1

Query: 362 IYVQGLNDNVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPT 421
           ++V GL + +    L   F + G      R  + M+    DK     +G   V+YE+P  
Sbjct: 142 LFVGGLAEEIDEKVLEREFSKFG------RITESMV--IRDKVRQVSRGFGFVTYENPMD 297

Query: 422 AKAAVEWFDGKDFQGSKLKVSLA 444
           A+ AV+  DGK+  G KL V  A
Sbjct: 298 AEEAVKHMDGKEILGKKLHVEDA 366
>11126
          Length = 1061

 Score = 35.8 bits (81), Expect = 0.055,   Method: Compositional matrix adjust.
 Identities = 28/93 (30%), Positives = 43/93 (46%)
 Frame = -3

Query: 357 SDNSAIYVQGLNDNVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSY 416
           +D  ++YV  ++   T ++L   F  CG V  N+ T      I  DK +G PKG A V +
Sbjct: 639 ADLRSVYVGNVDYGATAEELEQHFHGCGSV--NRVT------ILCDKYSGHPKGFAYVEF 484

Query: 417 EDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPP 449
            D  +   A        F+G ++KV+  R   P
Sbjct: 483 ADKDSVVTAKCTGMDSLFRGRQIKVTPKRTNRP 385
>14258
          Length = 1063

 Score = 33.9 bits (76), Expect = 0.23,   Method: Compositional matrix adjust.
 Identities = 17/49 (34%), Positives = 27/49 (55%)
 Frame = +2

Query: 399 IYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKK 447
           +++DK+T   K    VSY+ P +A+ A+   +G      +LKV L R K
Sbjct: 155 VFIDKQTNLSKCFGFVSYDSPMSAQDAISSMNGFQIGMKRLKVQLKRPK 301
>01065
          Length = 1033

 Score = 32.7 bits (73), Expect = 0.49,   Method: Compositional matrix adjust.
 Identities = 22/87 (25%), Positives = 40/87 (45%), Gaps = 1/87 (1%)
 Frame = +2

Query: 360 SAIYVQGLNDNVTLDDLADFFKQCG-VVKMNKRTGQPMIHIYLDKETGKPKGDATVSYED 418
           + I+V  L+ + +  ++ + FK+ G ++ +     QP I              A V Y  
Sbjct: 14  TRIHVGSLSSSTSTREIREEFKRFGDIIDLWMPRTQPTI--------------AFVVYRY 151

Query: 419 PPTAKAAVEWFDGKDFQGSKLKVSLAR 445
              A+ A+   DG+   G +++VSLAR
Sbjct: 152 EEDAEKAIRRMDGESMHGRRVRVSLAR 232
>25691
          Length = 768

 Score = 32.3 bits (72), Expect = 0.60,   Method: Compositional matrix adjust.
 Identities = 17/44 (38%), Positives = 23/44 (52%)
 Frame = -2

Query: 402 DKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLAR 445
           DK TG+  G   V+Y+    A  A+   +G   Q   +KVSLAR
Sbjct: 416 DKPTGQSLGYGFVNYKRQEDADKAIHTLNGLRLQNKTIKVSLAR 285
>33516
          Length = 449

 Score = 32.0 bits (71), Expect = 0.82,   Method: Compositional matrix adjust.
 Identities = 18/65 (27%), Positives = 32/65 (49%)
 Frame = +1

Query: 362 IYVQGLNDNVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPT 421
           I+V GL+ +   D L  +F Q G +            + ++++TGK +G   VS++DP T
Sbjct: 160 IFVGGLSWDTDQDSLQGYFSQFGEI--------TDCIVMMNQQTGKSRGFGFVSFKDPST 315

Query: 422 AKAAV 426
               +
Sbjct: 316 VDVIL 330
>00738
          Length = 1559

 Score = 32.0 bits (71), Expect = 0.86,   Method: Compositional matrix adjust.
 Identities = 22/85 (25%), Positives = 39/85 (45%), Gaps = 1/85 (1%)
 Frame = -2

Query: 362  IYVQGLNDNVTLDDLADFFKQCG-VVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPP 420
            I+V  L+ + +  ++ + FK+ G ++ +     QP I              A V Y    
Sbjct: 1261 IHVGSLSSSTSTREIREEFKRFGDIIDLWMPRTQPTI--------------AFVVYRYEE 1124

Query: 421  TAKAAVEWFDGKDFQGSKLKVSLAR 445
             A+ A+   DG+   G +++VSLAR
Sbjct: 1123 DAEKAIRRMDGESMHGRRVRVSLAR 1049
>08816
          Length = 566

 Score = 31.6 bits (70), Expect = 0.96,   Method: Composition-based stats.
 Identities = 22/82 (26%), Positives = 39/82 (47%)
 Frame = +1

Query: 362 IYVQGLNDNVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPT 421
           + V+ +  ++T  +L + F+  G VK ++        I +D+  G+P GDA V +     
Sbjct: 55  VTVRNVPFSLTWQELRERFQDIGDVKFSE--------ILMDQ--GRPSGDAVVRFGTSAD 204

Query: 422 AKAAVEWFDGKDFQGSKLKVSL 443
           A  A+   DG    G  ++V L
Sbjct: 205 AMRAINLVDGTRIDGRTVRVVL 270
>35180
          Length = 2181

 Score = 30.8 bits (68), Expect = 1.9,   Method: Compositional matrix adjust.
 Identities = 11/26 (42%), Positives = 20/26 (76%)
 Frame = -2

Query: 361 AIYVQGLNDNVTLDDLADFFKQCGVV 386
           ++YV+G  +++TLD L +FF+Q G +
Sbjct: 257 SVYVKGFPEDITLDTLMEFFEQHGKI 180
>25950
          Length = 417

 Score = 29.3 bits (64), Expect = 5.0,   Method: Composition-based stats.
 Identities = 21/92 (22%), Positives = 39/92 (42%)
 Frame = -2

Query: 358 DNSAIYVQGLNDNVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYE 417
           D  ++YV  ++   + ++L   F  CG +          + I  +K  G PKG A + + 
Sbjct: 287 DTRSVYVGNVDYGASAEELEAHFHGCGTIN--------RVTILCNKADGHPKGFAYIEFG 132

Query: 418 DPPTAKAAVEWFDGKDFQGSKLKVSLARKKPP 449
                + A+   +   F+G ++KV   R   P
Sbjct: 131 SKEYVETALA-MNETLFRGRQIKVMTKRTNRP 39
>14637
          Length = 455

 Score = 28.5 bits (62), Expect = 8.5,   Method: Compositional matrix adjust.
 Identities = 11/33 (33%), Positives = 20/33 (60%)
 Frame = -1

Query: 399 IYLDKETGKPKGDATVSYEDPPTAKAAVEWFDG 431
           +++DK+T   K    VSY+ P +A+ A+   +G
Sbjct: 110 VFIDKQTNLSKCFGFVSYDSPMSAQDAISSMNG 12
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|161016826|ref|NP_031900.3| receptor accessory protein
5 [Mus musculus]
         (189 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

18785                                                                  48   3e-06
07036                                                                  30   0.62 
19582                                                                  28   2.2  
21647                                                                  27   3.9  
16561                                                                  26   9.1  
>18785
          Length = 1091

 Score = 47.8 bits (112), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 27/94 (28%), Positives = 44/94 (46%)
 Frame = -3

Query: 51  FGYGASLLCNLIGFGYPAYISMKAIESPNKDDDTQWLTYWVVYGVFSIAEFFSDLFLSWF 110
           F      L  + G   PA  + +A+   NK++   W  YW+VYG     E   D F +W 
Sbjct: 969 FSLVTRFLIIIFGTLLPARNTHEALG--NKEELLTWSKYWIVYGCLMTVEIVGDTFFTWL 796

Query: 111 PFYYMLKCGFLLWCMAPSPANGAEMLYRRIIRPI 144
           PFY   K   +LW +  +P+  +  ++  I+ P+
Sbjct: 795 PFYGETKLLIVLWLVISAPS-ASVWIFDVILNPL 697
>07036
          Length = 1018

 Score = 30.0 bits (66), Expect = 0.62,   Method: Compositional matrix adjust.
 Identities = 21/83 (25%), Positives = 40/83 (48%), Gaps = 8/83 (9%)
 Frame = +1

Query: 47  LYLVFGYGASLL----CNLIGFG--YPAYI--SMKAIESPNKDDDTQWLTYWVVYGVFSI 98
           +Y V  +  + L    CN+I F   YP +     K +E+P  ++  +W+  +  Y +++ 
Sbjct: 622 MYCVLKHNKTKLPDVACNIIRFHSFYPWHNGGDYKHLEAPKDEETKKWVLIFNRYDLYTK 801

Query: 99  AEFFSDLFLSWFPFYYMLKCGFL 121
           +E   D+   W P+Y  L   +L
Sbjct: 802 SEIVPDIEALW-PYYQTLIDKYL 867
>19582
          Length = 797

 Score = 28.1 bits (61), Expect = 2.2,   Method: Compositional matrix adjust.
 Identities = 13/29 (44%), Positives = 17/29 (58%), Gaps = 4/29 (13%)
 Frame = -3

Query: 119 GFLLWCMAPSPANGAEML----YRRIIRP 143
           GF+L+C  PSP  G E +    Y+ II P
Sbjct: 396 GFILFCPVPSPVTGDEEVCV*TYQNIILP 310
>21647
          Length = 1648

 Score = 27.3 bits (59), Expect = 3.9,   Method: Compositional matrix adjust.
 Identities = 10/32 (31%), Positives = 21/32 (65%)
 Frame = -2

Query: 6   RERFDRFLHEKNCMTDLLAKLEAKTGVNRSFI 37
           +E F + ++  +CM+ L  K+  ++G++ SFI
Sbjct: 468 KENFFQLVNSTSCMSQLAHKVSVQSGLSLSFI 373
>16561
          Length = 2029

 Score = 26.2 bits (56), Expect = 9.1,   Method: Compositional matrix adjust.
 Identities = 15/31 (48%), Positives = 17/31 (54%)
 Frame = +3

Query: 18  CMTDLLAKLEAKTGVNRSFIALGVIGLVALY 48
           C+T +  K  AKT VN  F  LGV  L  LY
Sbjct: 624 CLTGMPVKTPAKTSVNDQF-CLGVTVLYRLY 713
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|30520239|ref|NP_848887.1| arylacetamide
deacetylase-like 1 [Mus musculus]
         (408 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

29447                                                                  49   3e-06
20420                                                                  33   0.16 
28981                                                                  33   0.26 
07330                                                                  30   1.2  
01109                                                                  28   6.9  
>29447
          Length = 472

 Score = 49.3 bits (116), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 18/41 (43%), Positives = 29/41 (70%)
 Frame = +1

Query: 342 ILTCEHDVLRDDGIMYAKRLESAGVNVTLDHFEDGFHGCMI 382
           ++  ++DVLRD+ +MYA RL  +GV V L H+++ FHG  +
Sbjct: 1   VIASQYDVLRDEAVMYAHRLLESGVKVKLKHYQNAFHGVFL 123
>20420
          Length = 694

 Score = 33.5 bits (75), Expect = 0.16,   Method: Compositional matrix adjust.
 Identities = 19/56 (33%), Positives = 27/56 (48%)
 Frame = -2

Query: 311 RIVQEIPQLLDAAASPLIAEQEVLEALPKTYILTCEHDVLRDDGIMYAKRLESAGV 366
           + V +  Q  D   SP    +     LP    +  E D LRDDG+ Y ++L+ AGV
Sbjct: 660 KYVADDSQKTDPVVSPY--HRPSFTGLPPALCVLAELDPLRDDGLAYCEKLKKAGV 499
>28981
          Length = 896

 Score = 32.7 bits (73), Expect = 0.26,   Method: Compositional matrix adjust.
 Identities = 32/139 (23%), Positives = 56/139 (40%), Gaps = 1/139 (0%)
 Frame = -3

Query: 270 NHTSLDVERAAALRARLDWTSLLPSSIKKNYKPIMQTTGNARIVQEIPQLLDAAASPLIA 329
            HT+L       ++ +  +  +L S   + +    + T N R+            SPL+ 
Sbjct: 882 KHTTL-------MKHKPTYLGMLISGCTEQFLCTSEDTKNVRV------------SPLL- 763

Query: 330 EQEVLEALPKTYILTCEHDVLRDDGIMYAKRLESAGVNVTLDHFEDGFHGCMIFTSWPTN 389
            Q     LP   IL  E D L+D    Y K+++ AG+       +   HG   F S P +
Sbjct: 762 -QTNFARLPPALILVPEVDPLKDACYEYKKKMKEAGIEAESLTLKGAVHG---FFSLPGH 595

Query: 390 FS-VGIRTRNSYIKWLDQN 407
           F+    R  +  + ++ +N
Sbjct: 594 FAETNRRALDKILSFMKKN 538
>07330
          Length = 746

 Score = 30.4 bits (67), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 15/41 (36%), Positives = 24/41 (58%)
 Frame = +1

Query: 109 VIYIHGGGWALASAKISYYDQLCTTMAEELNAVIVSIEYRL 149
           +I+IHGGG+ L SA     D   + +    + ++V I+YRL
Sbjct: 385 MIWIHGGGFTLGSA----LDYTPSVLVTSRDVIVVVIQYRL 495
>01109
          Length = 2130

 Score = 28.1 bits (61), Expect = 6.9,   Method: Compositional matrix adjust.
 Identities = 20/67 (29%), Positives = 31/67 (46%), Gaps = 3/67 (4%)
 Frame = -2

Query: 310 ARIVQEIPQLLDAAASPLIAEQEVLEALPKTYILTCEHDVLRDDGIMYAKRL---ESAGV 366
           A  ++++ Q  DAA +  +  Q  L  L       C HDV R  G +++  L    S  +
Sbjct: 251 AGALEQVHQAHDAARTKGVVAQVKLHQLAPCRYDGCSHDVARQRGFLFSGAL*TCHSIML 72

Query: 367 NVTLDHF 373
           + TLD F
Sbjct: 71  SQTLDVF 51
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31560670|ref|NP_032603.2| solute carrier family 3
(activators of dibasic and neutral amino acid transport), member 2
[Mus musculus]
         (526 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

17555                                                                  50   3e-06
27835                                                                  37   0.017
>17555
          Length = 541

 Score = 49.7 bits (117), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 40/142 (28%), Positives = 60/142 (42%), Gaps = 7/142 (4%)
 Frame = +1

Query: 54  FTGLSKEELLKVAGSPGWVRTRXXXXXXXXXXXXXXXXXXVVIIVRAPRCRELPVQRWWH 113
           F GL K+EL + A  P WVR R                  +VIIV APRC   P  +W++
Sbjct: 49  FIGLGKDELKRYAEDPFWVRLRWILFILFWVGWLAMLVSAIVIIVLAPRCPTRPDLKWYN 228

Query: 114 KGALYRIGDLQAFVGPDA-----GGIAGLKSHLEYLST-LKVKGLVLGPIHKNQKDEINE 167
           K   Y +   ++F   DA     G + G+K    Y++  +K   L +  I   + D    
Sbjct: 229 KDVSYNVYS-KSFFDGDADQDGYGDLDGIKEKQGYINNYIKSNILWISSILPTEDDNDRA 405

Query: 168 T-DLKQINPTLGSQEDFKDLLQ 188
             D K ++  +      + LLQ
Sbjct: 406 VLDYKTLDKKVWHHRQLQSLLQ 471
>27835
          Length = 559

 Score = 37.4 bits (85), Expect = 0.017,   Method: Compositional matrix adjust.
 Identities = 21/71 (29%), Positives = 36/71 (50%)
 Frame = +3

Query: 424 GKERSLLHGDFHALSSSPDLFSYIRHWDQNERYLVVLNFRDSGRSARLGASNLPAGISLP 483
           G   S  +GD++      D+FS++R +D  + +LV LNF +   +   G S      ++P
Sbjct: 27  GNYNSFHYGDYNEALVDDDVFSFVRDFDGEKGFLVALNFANVTVTKNYGGSYE----TIP 194

Query: 484 ASAKLLLSTDS 494
           + A + L T S
Sbjct: 195 SEATVQLRTGS 227
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6755911|ref|NP_035790.1| thioredoxin 1 [Mus musculus]
         (105 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

15159                                                                  47   3e-06
06936                                                                  37   0.002
03582                                                                  37   0.002
35861                                                                  35   0.009
28335                                                                  31   0.15 
21509                                                                  30   0.35 
04510                                                                  28   1.2  
30644                                                                  27   1.4  
36159                                                                  27   2.3  
>15159
          Length = 1945

 Score = 46.6 bits (109), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 21/36 (58%), Positives = 27/36 (75%)
 Frame = +3

Query: 5   IESKEAFQEALAAAGDKLVVVDFSATWCGPCKMIKP 40
           I S + F++A+   G +LVVVDF ATWCGPCK+I P
Sbjct: 90  ISSADDFEKAIQ--GGQLVVVDFHATWCGPCKVIAP 191

 Score = 26.9 bits (58), Expect = 2.1,   Method: Composition-based stats.
 Identities = 10/19 (52%), Positives = 14/19 (73%)
 Frame = +2

Query: 79  FYKKGQKVGEFSGANKEKL 97
           F++ G+K+ E  GAN EKL
Sbjct: 314 FFRDGKKIDELVGANHEKL 370
>06936
          Length = 2198

 Score = 37.0 bits (84), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 21/75 (28%), Positives = 31/75 (41%), Gaps = 2/75 (2%)
 Frame = +3

Query: 13   EALAAAGDKLVVVDFSATWCGPCKMIKPFFHSLCDKYSN--VVFLXXXXXXXXXXXXXXX 70
            E L    +K V+++F A WCG CK + P +  L +K  N   + +               
Sbjct: 1218 EELVNDPEKDVLIEFYAPWCGHCKTLAPKYDELAEKLKNEPEIVIAKMDATANDVPPPYD 1397

Query: 71   XKCMPTFQFYKKGQK 85
             +  PT  F  KG K
Sbjct: 1398 VRGFPTLYFAPKGSK 1442

 Score = 28.5 bits (62), Expect = 0.71,   Method: Compositional matrix adjust.
 Identities = 10/22 (45%), Positives = 15/22 (68%)
 Frame = +3

Query: 22  LVVVDFSATWCGPCKMIKPFFH 43
           L++V+F A WCG CK + P + 
Sbjct: 201 LMLVEFFAPWCGHCKKLAPQYE 266
>03582
          Length = 1967

 Score = 37.0 bits (84), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 14/31 (45%), Positives = 20/31 (64%)
 Frame = +3

Query: 21   KLVVVDFSATWCGPCKMIKPFFHSLCDKYSN 51
            K V V+F A WCG CK + P +  L DK+++
Sbjct: 1182 KGVFVEFYAPWCGHCKQLAPIWDELADKFTD 1274

 Score = 31.2 bits (69), Expect = 0.10,   Method: Compositional matrix adjust.
 Identities = 21/84 (25%), Positives = 36/84 (42%), Gaps = 4/84 (4%)
 Frame = +2

Query: 20  DKLVVVDFSATWCGPCKMIKPFF----HSLCDKYSNVVFLXXXXXXXXXXXXXXXXKCMP 75
           ++ V+V+F A WCG CK + P +     +L D+ S+V                   +  P
Sbjct: 164 NEFVLVEFYAPWCGHCKALAPEYAKAAQTLKDENSDVKLAKVDATIETSLGENMGVRGYP 343

Query: 76  TFQFYKKGQKVGEFSGANKEKLEA 99
           T +F    + +   +GA  + L A
Sbjct: 344 TLKFSVMEKILNIPAGAKLQTLSA 415
>35861
          Length = 850

 Score = 34.7 bits (78), Expect = 0.009,   Method: Compositional matrix adjust.
 Identities = 19/50 (38%), Positives = 29/50 (58%)
 Frame = +3

Query: 2   VKLIESKEAFQEALAAAGDKLVVVDFSATWCGPCKMIKPFFHSLCDKYSN 51
           VK++ SK   + AL  + D  V V+F A WCG CK + P +  L +K+ +
Sbjct: 576 VKVLVSKNFKEVALDKSKD--VFVEFYAPWCGHCKQLVPIWDELGEKFQD 719
>28335
          Length = 601

 Score = 30.8 bits (68), Expect = 0.15,   Method: Compositional matrix adjust.
 Identities = 10/26 (38%), Positives = 18/26 (69%)
 Frame = -2

Query: 21  KLVVVDFSATWCGPCKMIKPFFHSLC 46
           K V+++F A WCG C+ ++P ++ L 
Sbjct: 495 KDVLIEFYAPWCGHCQQLEPKYNELA 418
>21509
          Length = 754

 Score = 29.6 bits (65), Expect = 0.35,   Method: Compositional matrix adjust.
 Identities = 11/25 (44%), Positives = 16/25 (64%)
 Frame = -1

Query: 18  AGDKLVVVDFSATWCGPCKMIKPFF 42
           A ++  +V F A WCG CK +KP +
Sbjct: 316 AANRRTLVMFYAPWCGHCKKMKPAY 242
>04510
          Length = 685

 Score = 27.7 bits (60), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 10/19 (52%), Positives = 14/19 (73%)
 Frame = +2

Query: 22  LVVVDFSATWCGPCKMIKP 40
           L++V+F A WCG CK + P
Sbjct: 407 LMLVEFFAPWCGHCKKLAP 463
>30644
          Length = 845

 Score = 27.3 bits (59), Expect = 1.4,   Method: Compositional matrix adjust.
 Identities = 11/19 (57%), Positives = 13/19 (68%)
 Frame = -3

Query: 24  VVDFSATWCGPCKMIKPFF 42
           +V F A WCG CK +KP F
Sbjct: 414 LVMFYAPWCGYCKRMKPDF 358
>36159
          Length = 369

 Score = 26.9 bits (58), Expect = 2.3,   Method: Compositional matrix adjust.
 Identities = 9/24 (37%), Positives = 14/24 (58%)
 Frame = -1

Query: 28  SATWCGPCKMIKPFFHSLCDKYSN 51
            A WCG CK + P +  L +K+ +
Sbjct: 105 DAPWCGHCKQLVPIWDELGEKFQD 34
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|158854016|ref|NP_035673.3| S-phase kinase-associated
protein 1A [Mus musculus]
         (163 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

04928                                                                  47   4e-06
17755                                                                  27   4.9  
>04928
          Length = 785

 Score = 47.0 bits (110), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 30/123 (24%), Positives = 53/123 (43%), Gaps = 26/123 (21%)
 Frame = +3

Query: 46  PLPNVNAAILKKVIQWCTHHXXXXXXXXXXXXXXXRTD---------------------- 83
           P+P  ++  L+K++ WC  H                +D                      
Sbjct: 264 PVPVADSTALQKIVDWCEFHMNDIVPCINPELHTRDSDEEEPMGEAADGQQGAGVMVTNE 443

Query: 84  DIP----VWDQEFLKVDQGTLFELILAANYLDIKGLLDVTCKTVANMIKGKTPEEIRKTF 139
           D P     +D+ F  VD  TL+ +I  +++L+I  LLD + K +A+M++GKT +E++   
Sbjct: 444 DPPHNAEQFDRRFFSVDNLTLYHVIRVSSFLEINPLLDKSSKWLADMLRGKTAQEMKAIL 623

Query: 140 NIK 142
            I 
Sbjct: 624 AIS 632
>17755
          Length = 769

 Score = 26.6 bits (57), Expect = 4.9,   Method: Compositional matrix adjust.
 Identities = 8/19 (42%), Positives = 15/19 (78%)
 Frame = +1

Query: 131 TPEEIRKTFNIKNDFTEEE 149
           TP E+R+T +++NDF  ++
Sbjct: 337 TPAEVRQTLSLRNDFRSDD 393
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|82546887|ref|NP_848817.2| Rap GTPase interactor [Mus
musculus]
         (1070 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

27345                                                                  50   4e-06
03831                                                                  48   2e-05
20073                                                                  41   0.003
37239                                                                  39   0.010
29705                                                                  37   0.034
00637                                                                  31   3.2  
33912                                                                  30   5.8  
38751                                                                  30   6.2  
03681                                                                  30   7.4  
>27345
          Length = 496

 Score = 50.4 bits (119), Expect = 4e-06,   Method: Composition-based stats.
 Identities = 26/68 (38%), Positives = 42/68 (61%)
 Frame = +3

Query: 994  GAQGLYIQTLLPGSPAASDGRLSLGDQILEVNGSSLRGVSYMRAVDLIRHGGKKMRFLVA 1053
            G  G++I+TL  G  A  DGR+ + DQI+EV+G SL GV+   A  ++R+   ++ F + 
Sbjct: 15   GKLGIFIKTLTDGGAAQKDGRIQVNDQIIEVDGKSLVGVTQAYAASVLRNTSGQVTFHIG 194

Query: 1054 KSDMETAK 1061
            + D + AK
Sbjct: 195  R-DKDPAK 215
>03831
          Length = 1143

 Score = 48.1 bits (113), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 27/71 (38%), Positives = 41/71 (57%)
 Frame = +3

Query: 989  MHTPLGAQGLYIQTLLPGSPAASDGRLSLGDQILEVNGSSLRGVSYMRAVDLIRHGGKKM 1048
            +H   G  G +I  +  GSPA + G L  GD+I+EVNG+++   ++ + V  I+ GG + 
Sbjct: 183  LHAEKGKAGQFIGKVDEGSPAEAAG-LKAGDRIVEVNGTNIGNENHQQVVGRIKAGGDET 359

Query: 1049 RFLVAKSDMET 1059
            R LV   D ET
Sbjct: 360  RLLVV--DQET 386

 Score = 43.1 bits (100), Expect = 6e-04,   Method: Compositional matrix adjust.
 Identities = 24/76 (31%), Positives = 38/76 (50%)
 Frame = +3

Query: 989  MHTPLGAQGLYIQTLLPGSPAASDGRLSLGDQILEVNGSSLRGVSYMRAVDLIRHGGKKM 1048
            +H      G YI ++ P SPA + G L  GD+I+EVNG ++   ++   +  I+  G K 
Sbjct: 630  LHAEKDKPGQYIGSVDPNSPAETGG-LKEGDRIIEVNGENIETTNHTAVIQNIKSRGDKT 806

Query: 1049 RFLVAKSDMETAKKIR 1064
              LV     ++  K R
Sbjct: 807  SMLVVDKAADSYYKNR 854
>20073
          Length = 582

 Score = 41.2 bits (95), Expect = 0.003,   Method: Composition-based stats.
 Identities = 24/73 (32%), Positives = 39/73 (53%)
 Frame = +3

Query: 980  GLGMGLIDGMHTPLGAQGLYIQTLLPGSPAASDGRLSLGDQILEVNGSSLRGVSYMRAVD 1039
            GLG  ++ G      +  +YI  ++PG  A     L  GDQ+L VNG S+ G  + +AV+
Sbjct: 3    GLGFNVMGGKEQ---SSPIYISRIIPGGVADRLNCLKRGDQLLSVNGVSVEGEYHEKAVE 173

Query: 1040 LIRHGGKKMRFLV 1052
            L++     +R +V
Sbjct: 174  LLKLAQGSVRLVV 212
>37239
          Length = 453

 Score = 38.9 bits (89), Expect = 0.010,   Method: Composition-based stats.
 Identities = 16/38 (42%), Positives = 27/38 (71%)
 Frame = -2

Query: 1005 PGSPAASDGRLSLGDQILEVNGSSLRGVSYMRAVDLIR 1042
            P SPAA D R+ +GD++LE+NG+ L G  ++ A  +++
Sbjct: 449  PDSPAARDARIHVGDELLEINGNLLHGRCHLNASAIVK 336

 Score = 31.6 bits (70), Expect = 1.8,   Method: Composition-based stats.
 Identities = 12/28 (42%), Positives = 20/28 (71%)
 Frame = -3

Query: 994  GAQGLYIQTLLPGSPAASDGRLSLGDQI 1021
            G  G+YI+ +  G  AA DG+L++GD++
Sbjct: 85   GRHGIYIRHITIGGAAAKDGQLAVGDEL 2
>29705
          Length = 674

 Score = 37.4 bits (85), Expect = 0.034,   Method: Composition-based stats.
 Identities = 19/58 (32%), Positives = 30/58 (51%)
 Frame = -2

Query: 1006 GSPAASDGRLSLGDQILEVNGSSLRGVSYMRAVDLIRHGGKKMRFLVAKSDMETAKKI 1063
            G  AA DGRL L D I++V    +   ++  AVD ++  G ++   V +  + T K I
Sbjct: 622  GGAAAEDGRLRLNDIIVKVGTEDVSNTTHTAAVDALKRSGNRVYLQVKRLKIPTEKVI 449
>00637
          Length = 1050

 Score = 30.8 bits (68), Expect = 3.2,   Method: Composition-based stats.
 Identities = 22/69 (31%), Positives = 33/69 (47%), Gaps = 1/69 (1%)
 Frame = -2

Query: 561 VVLYAFQQCVYYLSKCLYVCLPALLECPPFQTERRESWR-SGPALPEELRRVVSVFQATL 619
           V +Y       Y+  C YVC+ A +  P  Q ERR+ W   G      L+   SV + T+
Sbjct: 755 VYMYVCMYICXYV*LCXYVCMYACM--PLLQLERRDEWGWGGCQFGGRLKGSKSV-RHTV 585

Query: 620 DLLQQLQMH 628
           +L Q  ++H
Sbjct: 584 ELWQLAKLH 558
>33912
          Length = 753

 Score = 30.0 bits (66), Expect = 5.8,   Method: Composition-based stats.
 Identities = 10/22 (45%), Positives = 15/22 (68%)
 Frame = +3

Query: 566 FQQCVYYLSKCLYVCLPALLEC 587
           FQ+C+Y   +C+ VC   L+EC
Sbjct: 177 FQKCMYGFCECVCVCATILIEC 242
>38751
          Length = 329

 Score = 29.6 bits (65), Expect = 6.2,   Method: Composition-based stats.
 Identities = 14/39 (35%), Positives = 25/39 (64%)
 Frame = +3

Query: 1006 GSPAASDGRLSLGDQILEVNGSSLRGVSYMRAVDLIRHG 1044
            G  A   G L++GD+IL+VNG+    +++  AV ++R+ 
Sbjct: 63   GCQAEQQG-LNIGDRILDVNGTDFTHLTHAEAVTIMRNA 176
>03681
          Length = 1255

 Score = 29.6 bits (65), Expect = 7.4,   Method: Compositional matrix adjust.
 Identities = 19/78 (24%), Positives = 35/78 (44%)
 Frame = -2

Query: 56  STQLSAPGVLKVFGDSVCTGTHYKSVLATGSSSAQELVKEALERYALDPECAGQYVLCDV 115
           + +LS P +LK   D+V +  H+ S L    +S +    + LE+Y L   C   +     
Sbjct: 834 NIKLSLPXLLKTQQDAVESDAHFFSNLPNN*TSHKINENKLLEKYKLKNRCIVSF----S 667

Query: 116 VGQAGDSGQRWQAQCFRV 133
           VG++     +W     ++
Sbjct: 666 VGESSFGMVQWTEDLLKM 613
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|21717805|ref|NP_663358.1| rhodopsin [Mus musculus]
         (348 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

26601                                                                  48   5e-06
35147                                                                  48   7e-06
38474                                                                  47   9e-06
26971                                                                  47   2e-05
31540                                                                  46   2e-05
05928                                                                  44   1e-04
00963                                                                  42   5e-04
15025                                                                  41   6e-04
27862                                                                  37   0.011
17845                                                                  32   0.30 
37023                                                                  31   0.63 
15134                                                                  31   0.93 
04628                                                                  28   3.8  
12403                                                                  28   4.5  
09074                                                                  28   6.3  
>26601
          Length = 397

 Score = 48.1 bits (113), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 26/106 (24%), Positives = 53/106 (50%)
 Frame = -2

Query: 39  MLAAYMFLLIVLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTTLYTS 98
           ++   +  +IV    +N   ++  +  +K    ++Y +L LA++DL      +   + ++
Sbjct: 318 IVGCLLLAIIVSAVVMNSFVIWSFIVRRKTVVSVDYYILTLAISDLCSPIFAYPFAMVST 139

Query: 99  LHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMS 144
               ++FG TGC + GF     G + ++ L  L I RY+ VC P++
Sbjct: 138 FSHGWIFGETGCLVNGFLGFFFGIVDIFILSTLGITRYICVCHPIT 1
>35147
          Length = 670

 Score = 47.8 bits (112), Expect = 7e-06,   Method: Compositional matrix adjust.
 Identities = 52/203 (25%), Positives = 102/203 (50%), Gaps = 11/203 (5%)
 Frame = +1

Query: 35  WQFS---MLAAYMFLLIVLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGF 91
           W F+   +LA    +   L    N + L V ++H+ +RT  N  L+NLAVADL +     
Sbjct: 13  WNFAFSVILATIESISAFLAVVGNSMVLTVVIRHRGMRTRTNLFLVNLAVADLLVGATVV 192

Query: 92  TTTLYTSLHGYFVFG-PTG--CNLEGFFATLGGEIALWSLVVLAIERYVVVCKPM-SNFR 147
              + T + G +VFG P G  C + G+        ++ +L+ +++ ++  + +P+ S+F+
Sbjct: 193 PFAITTIIEGRWVFGNPNGVFCTINGWLNCFCLVASIHTLMYISVHKHYSITQPLGSHFK 372

Query: 148 FGENHAIMGVVFTWIMALACAAPPLV-GWSRYIPEGMQCSCGIDYYTLKPEVNNESFVIY 206
             +   I+G++    +  A ++   V G S    +     CG +Y    P+   +S+ I+
Sbjct: 373 LRQ---ILGMMAAAWVWAAVSSTITVTGLSSVRYKEGTSQCGPEY----PD-GLKSY-IF 525

Query: 207 MFVVHFT---IPMIVIFFCYGQL 226
             ++ FT   IP+I++ +CY ++
Sbjct: 526 HGIIQFTNILIPVIILTYCYARM 594
>38474
          Length = 550

 Score = 47.4 bits (111), Expect = 9e-06,   Method: Compositional matrix adjust.
 Identities = 35/133 (26%), Positives = 57/133 (42%), Gaps = 12/133 (9%)
 Frame = +3

Query: 195 KPEVNNESFVIYMFVVHFTIPMIVIFFCYGQLVFTVXXXXXXXX--------XXXXXXXX 246
           KP+   + F +   V+ + +P  +I FCY  +   +                        
Sbjct: 120 KPQAR-QFFTVTSLVLQYIVPCTIITFCYSMVSRALKKRSKVKIGSGARSREREEQEIRR 296

Query: 247 XKEVTRMVIIMVIFFLICWLPYASVAFYIFTHQGSNFGPIFMTLPAFFAK----SSSIYN 302
            K   +M+I MVI F+ CW+P  +V+  +  +Q S     + TL  F A     SS+IYN
Sbjct: 297 KKRTNKMLIAMVIIFMCCWMPL-NVSLLVREYQDSVEHWYYFTLVFFIAHVIAMSSTIYN 473

Query: 303 PVIYIMLNKQFRN 315
           P +Y  +N  F+ 
Sbjct: 474 PFLYAWMNDNFKK 512
>26971
          Length = 467

 Score = 46.6 bits (109), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 43/139 (30%), Positives = 64/139 (46%), Gaps = 5/139 (3%)
 Frame = -1

Query: 55  NFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGF----TTTLYTSLHGYFVFGPTGC 110
           N L L    + + LRT  N  + +LA AD+ +  G F        Y  L   F     GC
Sbjct: 437 NTLVLLAIAKTRSLRTVTNCFIGSLAAADVMV--GLFIPPSVILSYVGLPRDF----YGC 276

Query: 111 NLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNFRFGE-NHAIMGVVFTWIMALACAA 169
            L      L   I+L+SL+ +A+ER++ V  P    R    N A++ VV TW++A+    
Sbjct: 275 VLVNTMVVLITNISLFSLLAVALERFLAVKHPFLYQRVMTINRALVVVVITWVLAIVIGL 96

Query: 170 PPLVGWSRYIPEGMQCSCG 188
            P +GW+    EG   +C 
Sbjct: 95  IPTMGWNLG-KEGFDNTCA 42
>31540
          Length = 426

 Score = 46.2 bits (108), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 35/102 (34%), Positives = 53/102 (51%), Gaps = 4/102 (3%)
 Frame = +1

Query: 46  LLIVLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTTLYTSLHGYFVF 105
           LL+V+G   N L +YV  +  K RT  NY +L +A+ DL     G  T +Y  L  +  +
Sbjct: 43  LLMVIGVVGNVLVIYVYRRRFK-RTSSNYFILTMAIFDLVACLIGMPTEIYDLLKPFTFY 219

Query: 106 GPTGCNL----EGFFATLGGEIALWSLVVLAIERYVVVCKPM 143
              GC L    E F  T+ G + +  LV +A +RY  +C+P+
Sbjct: 220 SEFGCKLFRGTENF--TIYGSVVV--LVEIAFDRYFKICRPL 333
>05928
          Length = 1549

 Score = 43.5 bits (101), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 51/258 (19%), Positives = 104/258 (40%), Gaps = 16/258 (6%)
 Frame = -3

Query: 74   YILLNLAVADLFMVFGGFTTTLYTSLHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAI 133
            Y   +LA AD+ +V    +  +   + G+++FG   C +      +    ++ SL ++ I
Sbjct: 1244 YFFFSLAAADMLVVVMVMSFAIVNDVLGHWLFGLRFCLIWVSLDIMCSTASILSLCLICI 1065

Query: 134  ERYVVVCKPMS-NFRFGENHAIMGVVFTWIMALACAAPPL-VGWSRYIPEGMQCSCGIDY 191
            +R+  +  P+    R      +  +   W++++  A  PL +GW  ++P  +     ID 
Sbjct: 1064 DRFCQIQYPLQYELRLSVKRIVFLIFLVWVISICIAFIPLQLGW--HLPP-LNERAPIDD 894

Query: 192  YTLKPEVNNESFVIYMFVVHFTIPMIVIFFCYGQLVFT--------------VXXXXXXX 237
                 +++ E + +    + F IP +++   Y ++                 V       
Sbjct: 893  SFCVLDISFE-YALVSSSISFYIPCVIMVSIYLKIYLLANKHFKNIIRSQVHVRLETQKL 717

Query: 238  XXXXXXXXXXKEVTRMVIIMVIFFLICWLPYASVAFYIFTHQGSNFGPIFMTLPAFFAKS 297
                       +    + I++  FL+CWLP+  V   I     +   PI   +  +   +
Sbjct: 716  GGQQKTSISHHKAAITIGILMGVFLVCWLPFFIVN-PIAAKCAACVPPILFVIFTWMGYA 540

Query: 298  SSIYNPVIYIMLNKQFRN 315
            +S  NP+IY + N  FRN
Sbjct: 539  NSCLNPIIYSLFNSDFRN 486
>00963
          Length = 905

 Score = 41.6 bits (96), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 30/93 (32%), Positives = 48/93 (51%), Gaps = 7/93 (7%)
 Frame = -1

Query: 248 KEVTRMVIIMVIFFLICWLPY----ASVAFYIFTHQGSNFGPIFMTLPAFF--AKSSSIY 301
           K+V +M++ ++  F+ICW P        AF +  H   N+G +     AF+  A ++S  
Sbjct: 476 KQVIKMLVAVIAIFVICWAPILVSNVLTAFQVLHHL--NYGYLKPMRQAFYLMAYANSCV 303

Query: 302 NPVIYIMLNKQFRNCMLTTLC-CGKNPLGDDDA 333
           NP+IY  +++ FR   L  +C C K   G D A
Sbjct: 302 NPLIYGFMSRHFRQTFLHAICTCVK---GRDYA 213
>15025
          Length = 449

 Score = 41.2 bits (95), Expect = 6e-04,   Method: Compositional matrix adjust.
 Identities = 19/63 (30%), Positives = 35/63 (55%)
 Frame = +1

Query: 252 RMVIIMVIFFLICWLPYASVAFYIFTHQGSNFGPIFMTLPAFFAKSSSIYNPVIYIMLNK 311
           ++++  ++ F++CW PYA ++F      G+  G     +P   AKS S  NP+ Y +  K
Sbjct: 61  KIILTTMVVFMLCWTPYALMSFA--ASLGTEIGVGASVIPTIMAKSHSAINPIAYFVCFK 234

Query: 312 QFR 314
           ++R
Sbjct: 235 KYR 243
>27862
          Length = 371

 Score = 37.0 bits (84), Expect = 0.011,   Method: Compositional matrix adjust.
 Identities = 29/107 (27%), Positives = 52/107 (48%), Gaps = 1/107 (0%)
 Frame = +3

Query: 27  PQYYLAEPWQFSMLAAYMFLLIVLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFM 86
           PQY  A  +  + +   + LL ++G   N +T+   + H+KLRT  N  +++LA+ADL +
Sbjct: 60  PQYGPAGVYGVTAVLLLVPLLTIVG---NSVTILAVLTHRKLRTKTNAFIVSLAIADLCV 230

Query: 87  VFGGFTTTLYTSLHGY-FVFGPTGCNLEGFFATLGGEIALWSLVVLA 132
                   +Y  L+   ++ G   C L   F  +   + ++ L  LA
Sbjct: 231 SLLVMPFAIYQQLNNKVWLLGDLLCRLSASFDVMMCTVTIFHLSSLA 371
>17845
          Length = 917

 Score = 32.3 bits (72), Expect = 0.30,   Method: Compositional matrix adjust.
 Identities = 21/118 (17%), Positives = 52/118 (44%), Gaps = 11/118 (9%)
 Frame = -2

Query: 209 VVHFTIPMIVIFFCYGQLVFTVXXXXX---XXXXXXXXXXXXKEVTRMVIIMVIFFLICW 265
           +V + +P++V+   Y  + + +                    ++V +M++ +++ F++CW
Sbjct: 904 IVMYLLPVLVMIIAYSIITYRLVTRKLPGFLNATISAQERAKRKVIKMLVAVLVCFVVCW 725

Query: 266 LPYASVAFY--------IFTHQGSNFGPIFMTLPAFFAKSSSIYNPVIYIMLNKQFRN 315
            P   +  Y        +   + S++  I   +  + A  +S  NP++Y   N++FR 
Sbjct: 724 SPQQCLLMYGVFKPYLGVTVGEASDYHTI-KYVALYVAYLNSALNPILYCGFNEKFRQ 554
>37023
          Length = 719

 Score = 31.2 bits (69), Expect = 0.63,   Method: Compositional matrix adjust.
 Identities = 17/59 (28%), Positives = 30/59 (50%)
 Frame = +3

Query: 285 PIFMTLPAFFAKSSSIYNPVIYIMLNKQFRNCMLTTLCCGKNPLGDDDASATASKTETS 343
            +F T+       +S  N V+Y +  K+FR  +   L   K+P G D   +T ++++TS
Sbjct: 30  QLFYTVCTVLVTINSSLNFVLYCLFGKKFRMVLCHILRLKKDPRGRDQYRSTGNQSKTS 206
>15134
          Length = 659

 Score = 30.8 bits (68), Expect = 0.93,   Method: Compositional matrix adjust.
 Identities = 15/78 (19%), Positives = 35/78 (44%), Gaps = 7/78 (8%)
 Frame = -3

Query: 248 KEVTRMVIIMVIFFLICWLPYASVAFYIFTHQGSNFGPI-------FMTLPAFFAKSSSI 300
           +++ ++++ +V+ F IC  PY ++  +           I        + L      S+  
Sbjct: 354 RQMVQIIVTVVMIFFICHTPYRALVLWTMFEDRRTLAEINFESYLTLLYLTRILLYSNHA 175

Query: 301 YNPVIYIMLNKQFRNCML 318
            NP +Y  ++++FR  +L
Sbjct: 174 INPFVYNFVSRKFRRALL 121
>04628
          Length = 940

 Score = 28.5 bits (62), Expect = 3.8,   Method: Compositional matrix adjust.
 Identities = 14/51 (27%), Positives = 29/51 (56%)
 Frame = +1

Query: 285 PIFMTLPAFFAKSSSIYNPVIYIMLNKQFRNCMLTTLCCGKNPLGDDDASA 335
           P F  L +    SSS+  P ++ ++++  ++C++T+    +NP G +  SA
Sbjct: 760 PNF*KLCSILVSSSSMR*PRLFRIIDRGAKSCIVTSFLYERNPPGRNGHSA 912
>12403
          Length = 595

 Score = 28.5 bits (62), Expect = 4.5,   Method: Compositional matrix adjust.
 Identities = 16/44 (36%), Positives = 25/44 (56%), Gaps = 1/44 (2%)
 Frame = -1

Query: 273 FYIFTHQGSNFGPIFM-TLPAFFAKSSSIYNPVIYIMLNKQFRN 315
           FY F H  +N  P+F   +P++F K  S  +   YI+LN  F++
Sbjct: 262 FYPFLHYPANISPVFEDAMPSYFGKVVSGMSLKTYILLNAIFKS 131
>09074
          Length = 465

 Score = 27.7 bits (60), Expect = 6.3,   Method: Compositional matrix adjust.
 Identities = 23/115 (20%), Positives = 47/115 (40%), Gaps = 1/115 (0%)
 Frame = -2

Query: 109 GCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNFRFGENHAIMGVVF-TWIMALAC 167
           GC    F    G  + +   +++ + RY V  + +          + G V    I AL  
Sbjct: 437 GCQYYAFTVYTGTLMIVLCYLLITVHRYRVFVQRVPADSADTRRWVSGSVLGALIYALCW 258

Query: 168 AAPPLVGWSRYIPEGMQCSCGIDYYTLKPEVNNESFVIYMFVVHFTIPMIVIFFC 222
           +  P +GW  +  E    SC +++ T        + +++ F+  + +P+ V+  C
Sbjct: 257 SVCPFLGWGSFAQEPFGTSCSLNWVTKNSADKIYNVMVFAFI--YLMPLGVMVGC 99
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|33563258|ref|NP_034444.1| guanine nucleotide binding
protein (G protein), gamma transducing activity polypeptide 1 [Mus
musculus]
         (74 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

13602                                                                  45   5e-06
16030                                                                  45   5e-06
02659                                                                  45   5e-06
>13602
          Length = 400

 Score = 45.4 bits (106), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 27/68 (39%), Positives = 43/68 (63%), Gaps = 1/68 (1%)
 Frame = -2

Query: 7   EDLTEKDKLKMEVDQLKKEVTLERMMVSKCCEEVRDYIEERSGEDPLVKGIPE-DKNPFK 65
           E L ++ +L   ++QL+ E  + RM VS+C ++++ Y E    ED L++G  +  +NPFK
Sbjct: 303 EGLQQQRRL---IEQLRCEAQITRMRVSQCIDDLQKYCEAHIEEDYLIRGFSKPSENPFK 133

Query: 66  ELKGGCVI 73
           E KGGC I
Sbjct: 132 E-KGGCNI 112
>16030
          Length = 425

 Score = 45.4 bits (106), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 27/68 (39%), Positives = 43/68 (63%), Gaps = 1/68 (1%)
 Frame = +2

Query: 7   EDLTEKDKLKMEVDQLKKEVTLERMMVSKCCEEVRDYIEERSGEDPLVKGIPE-DKNPFK 65
           E L ++ +L   ++QL+ E  + RM VS+C ++++ Y E    ED L++G  +  +NPFK
Sbjct: 134 EGLQQQRRL---IEQLRCEAQITRMRVSQCIDDLQKYCEAHIEEDYLIRGFSKPSENPFK 304

Query: 66  ELKGGCVI 73
           E KGGC I
Sbjct: 305 E-KGGCNI 325
>02659
          Length = 1434

 Score = 45.4 bits (106), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 27/68 (39%), Positives = 43/68 (63%), Gaps = 1/68 (1%)
 Frame = -1

Query: 7    EDLTEKDKLKMEVDQLKKEVTLERMMVSKCCEEVRDYIEERSGEDPLVKGIPE-DKNPFK 65
            E L ++ +L   ++QL+ E  + RM VS+C ++++ Y E    ED L++G  +  +NPFK
Sbjct: 1302 EGLQQQRRL---IEQLRCEAQITRMRVSQCIDDLQKYCEAHIEEDYLIRGFSKPSENPFK 1132

Query: 66   ELKGGCVI 73
            E KGGC I
Sbjct: 1131 E-KGGCNI 1111
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|54020730|ref|NP_598527.2| RIKEN cDNA C920006C10 [Mus
musculus]
         (819 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

34495                                                                  50   5e-06
05117                                                                  31   1.7  
>34495
          Length = 267

 Score = 49.7 bits (117), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 32/88 (36%), Positives = 46/88 (52%)
 Frame = -2

Query: 321 AVAIAAKGSIGPTVLEVFNTLLKHLRLSVELEANDXXXXXXXXXXXXXXDNDEKIVQNAV 380
             A   +GSIGP+VLEVFN LL+HLR+SV+ + ++               +D +    +V
Sbjct: 239 GCAYLRRGSIGPSVLEVFNNLLRHLRISVDSKGSN----QAQSTAEVHFQDDHRQHYRSV 72

Query: 381 IQTIGFFGSNLPDYQRSEIMMFIMGKVP 408
           + TI      L    RS  +MF+MGK P
Sbjct: 71  LPTICLTTRKL----RS--LMFVMGKFP 6
>05117
          Length = 3479

 Score = 31.2 bits (69), Expect = 1.7,   Method: Compositional matrix adjust.
 Identities = 18/61 (29%), Positives = 29/61 (47%), Gaps = 4/61 (6%)
 Frame = -1

Query: 142 FFVSRFSAMCHSCHSDPEIRT---EIRIAGIRGIQG-VVRKTVNDELRATIWEPQHMDKI 197
           FF++ FS++   CH  P++ T    I +  + G  G   R+ V  E R   W P + D  
Sbjct: 560 FFLNLFSSIIFCCHFHPKVETRVSNILLTMMSG*NG*EAREPVEVETRGPSWHPHNTDAS 381

Query: 198 V 198
           +
Sbjct: 380 I 378
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6755002|ref|NP_035182.1| programmed cell death 6
interacting protein [Mus musculus]
         (869 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

28978                                                                  50   5e-06
26948                                                                  33   0.36 
04112                                                                  30   5.2  
>28978
          Length = 438

 Score = 49.7 bits (117), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 41/142 (28%), Positives = 68/142 (47%), Gaps = 13/142 (9%)
 Frame = -1

Query: 216 LANQAADYFGDAFK---QCQYKDTLPKEVFP----TLAAKQCIMQANAEYHQSILAKQQK 268
           ++ Q  D++  A K   QC  +  +    F      +  K    Q    Y+ +  +++Q 
Sbjct: 438 VSAQVVDFYRLALKNLDQCNAEQIINSRSFKDWRKRIELKTAFYQCITHYYVARQSEEQS 259

Query: 269 KFGEEIARLQHAAEL-----IKNVASRYDEYVNVKDFS-DKINRALTAAKKDNDFIYHDR 322
           ++G+ +A LQ AAEL     +K   +   E      F+ D +   L +A+KDNDFIYH++
Sbjct: 258 RWGDRLAYLQ-AAELKLNDALKLAKNEVPEMQEALRFAQDVVGGKLQSAQKDNDFIYHEK 82

Query: 323 VPDLKDLDPIGKATLVKPTPVN 344
           +P L  L  +  A LVK  P +
Sbjct: 81  IPPLDTLPEVKGAPLVKGIPFD 16
>26948
          Length = 2380

 Score = 33.5 bits (75), Expect = 0.36,   Method: Compositional matrix adjust.
 Identities = 17/49 (34%), Positives = 30/49 (61%), Gaps = 2/49 (4%)
 Frame = -1

Query: 175  PTVDISPDTVGTLSLIMLAQAQEVFFLKATRDKMKDAII--AKLANQAA 221
            P++D+  DT+  L +++LAQAQE    +      K+ ++  A+LA +AA
Sbjct: 2344 PSMDMQSDTLSMLCVLLLAQAQECVMEERLMQWGKEGVVVNAQLAREAA 2198
>04112
          Length = 973

 Score = 29.6 bits (65), Expect = 5.2,   Method: Composition-based stats.
 Identities = 12/36 (33%), Positives = 22/36 (61%)
 Frame = -1

Query: 355 FEKMVPVSVQQSLAVFSQRKADLVNRSIAQMREATT 390
           F +M+P  + +SL+VFS++K   V   + + R+  T
Sbjct: 892 FSRMIP*QLNKSLSVFSRKKGRFVFNKLKKTRQQAT 785
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31560264|ref|NP_079617.2| abhydrolase domain
containing 6 [Mus musculus]
         (336 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

05344                                                                  48   6e-06
09813                                                                  47   1e-05
25689                                                                  46   2e-05
32572                                                                  42   5e-04
00871                                                                  37   0.011
29730                                                                  31   0.64 
17407                                                                  30   1.6  
32965                                                                  30   1.8  
>05344
          Length = 1178

 Score = 47.8 bits (112), Expect = 6e-06,   Method: Compositional matrix adjust.
 Identities = 42/163 (25%), Positives = 74/163 (45%), Gaps = 16/163 (9%)
 Frame = -2

Query: 70  HKPSILMLHGFSAHKDMWLSVVKFLPKNLHLVCVDMPGHEGTTRSS--------LDDLSI 121
           ++  IL LHG+  +   +  +   LP +  ++ +D+PGH  ++            D +S+
Sbjct: 973 NRQPILALHGWQDNCGSFDRLCPLLPADCSVLAIDLPGHGNSSHYPKGMQYFIFWDGISL 794

Query: 122 VGQVKRIHQFVECLKLNKKPFHLIGTSMGGHVAGVYAAYYPSDVCSLSLVCPAGLQYSTD 181
           + ++ R        K N K   L+G S+GG +  +YAA +P++V  L  +  AG      
Sbjct: 793 IRRIVR--------KFNWKNVVLMGHSLGGALTFMYAASFPNEVSKLINIDIAG------ 656

Query: 182 NPFVQRLKELEESA--AIQKIPLIPSTPE------EMSEMLQL 216
            P V+ +K + E    A+ K     + PE         EM+QL
Sbjct: 655 -PTVRSVKRMAEGTGKALDKFLDYETLPESKQPCYSYEEMIQL 530
>09813
          Length = 765

 Score = 47.0 bits (110), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 61/231 (26%), Positives = 97/231 (41%), Gaps = 15/231 (6%)
 Frame = -2

Query: 120 SIVGQVKRIHQFVECLKLNKKPFHLIGTSMGGHVAGVYAAYYPSDVCSLSLV-CPAGLQY 178
           SI   V  + Q +    L  K   L+G   GG VA   A  YP  V  L ++ CP+   Y
Sbjct: 761 SIDKLVDDLRQLIA--TLGYKKCVLVGHDWGGLVAWALAQNYPDLVQQLVILNCPSTPAY 588

Query: 179 STDNPFVQRLKELEES--AAIQKIPLIPS---TPEEMSEMLQLCSYVRFKVPQQILQGLV 233
                    L+++++S   A  ++P +P    T  +M  M  +       V    +    
Sbjct: 587 F--KLLASNLQQMKKSWYVAFFQMPWVPEMFLTVSDMDFMKDMFVGPTSGVKSDSMTD-E 417

Query: 234 DVRIPHNSFYRK-------LFLEIVNEKSRYSLHENMD-KIKVPTQIIWGKQDQVLDVSG 285
           DV     +F R         +  I+   S +    + D K+  PT I+WG QD  L+   
Sbjct: 416 DVEAYKYTFQRNGLTCPINYYRAIMRCSSTFFRMTSADLKVTCPTLIVWGCQDSALERDL 237

Query: 286 ADILAKSISNS-QVEVLENCGHSVVMERPRKTAKLIVDFLASVHNTDNKKL 335
           A + A+++S    V+ +ENC H   M++ ++    I  FL   H+T  K L
Sbjct: 236 AALSAETVSGQVCVKYIENCSHWAPMDQHQEVNDHIRQFL---HSTSKKAL 93
>25689
          Length = 546

 Score = 46.2 bits (108), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 22/67 (32%), Positives = 41/67 (61%)
 Frame = +3

Query: 262 NMDKIKVPTQIIWGKQDQVLDVSGADILAKSISNSQVEVLENCGHSVVMERPRKTAKLIV 321
           N  K K+PT +++G QD+ L    A+ L K++ N+ +EV+ N GH+  ++ P+    L+ 
Sbjct: 207 NYPKSKIPTLVVYGAQDENLGKQSAEHL-KALPNANMEVIANAGHACYLDXPQHFHSLLQ 383

Query: 322 DFLASVH 328
            FL +++
Sbjct: 384 HFLDTLN 404
>32572
          Length = 286

 Score = 41.6 bits (96), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 25/72 (34%), Positives = 39/72 (54%), Gaps = 1/72 (1%)
 Frame = +2

Query: 265 KIKVPTQIIWGKQDQVLDVSGADILAKSISNS-QVEVLENCGHSVVMERPRKTAKLIVDF 323
           K+  PT I+WG QD  L+   A + A+++S    V+ +ENC H   M++ ++    I  F
Sbjct: 8   KVTCPTLIVWGCQDSALERDLAALSAETVSGQVCVKYIENCSHWAPMDQHQEVNBHIRQF 187

Query: 324 LASVHNTDNKKL 335
           L   H+T  K L
Sbjct: 188 L---HSTSKKXL 214
>00871
          Length = 804

 Score = 37.0 bits (84), Expect = 0.011,   Method: Compositional matrix adjust.
 Identities = 20/62 (32%), Positives = 34/62 (54%), Gaps = 1/62 (1%)
 Frame = +1

Query: 266 IKVPTQIIWGKQDQVLDVSGADILAKSISNS-QVEVLENCGHSVVMERPRKTAKLIVDFL 324
           + +PT I+WG++D  LD+   D+ +K    S  V+ +++  H V M+ P+     I  FL
Sbjct: 34  VTMPTLIVWGEKDGALDIELVDLCSKRCQGSVSVQRVDSASHWVQMDCPQLVNTHITQFL 213

Query: 325 AS 326
            S
Sbjct: 214 HS 219
>29730
          Length = 427

 Score = 31.2 bits (69), Expect = 0.64,   Method: Compositional matrix adjust.
 Identities = 11/23 (47%), Positives = 16/23 (69%)
 Frame = +1

Query: 50  VRYAHHEDYQFCYSFRGRPGHKP 72
           V++ HH D+Q C+  RGRP  +P
Sbjct: 358 VQFGHHTDHQVCHPVRGRPQREP 426
>17407
          Length = 1465

 Score = 29.6 bits (65), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 9/80 (11%)
 Frame = -1

Query: 42  WRRTLGMQVRYAHHEDYQFCYSFRGR-----PGHKPSILMLHGFSAHKDMWLS---VVKF 93
           WRR L  QV   H E+ QFC+           GH+ S+  L  FS H  + L+   ++ F
Sbjct: 475 WRRNLVGQVGNTHVEEGQFCFQHVPNHHLQLAGHRRSLNSLVYFSGHSRINLACNHLLSF 296

Query: 94  LPK-NLHLVCVDMPGHEGTT 112
           L + N H+ C       G +
Sbjct: 295 LQQFNSHVSCSRSHXQNGVS 236
>32965
          Length = 661

 Score = 29.6 bits (65), Expect = 1.8,   Method: Compositional matrix adjust.
 Identities = 15/37 (40%), Positives = 19/37 (51%)
 Frame = +3

Query: 55  HEDYQFCYSFRGRPGHKPSILMLHGFSAHKDMWLSVV 91
           H   Q  +  RGRPG+K  +LML   +  K  W S V
Sbjct: 525 HVHVQLKHKLRGRPGNK*KMLMLTKQTQMKSSWESCV 635
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|85861252|ref|NP_080666.2| UBX domain containing 2
[Mus musculus]
         (506 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

34524                                                                  49   6e-06
00527                                                                  44   1e-04
02083                                                                  31   0.92 
20041                                                                  31   0.94 
11347                                                                  30   3.2  
06341                                                                  29   3.5  
>34524
          Length = 677

 Score = 48.5 bits (114), Expect = 6e-06,   Method: Compositional matrix adjust.
 Identities = 21/30 (70%), Positives = 24/30 (80%)
 Frame = +2

Query: 477 KKEGKIYRLRTQDDGEDENNTWNGNSTQQM 506
           ++EG I RLR  DD +DEN TWNGNSTQQM
Sbjct: 71  RQEGNIRRLRNMDDEDDENATWNGNSTQQM 160
>00527
          Length = 716

 Score = 44.3 bits (103), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 26/78 (33%), Positives = 36/78 (46%), Gaps = 1/78 (1%)
 Frame = -2

Query: 315 STIARIQFRLPDGSSFTNQFPSDAPLEEARQFAAQTV-GNTYGNFSLATMFPRREFTRED 373
           ST   IQ RLP+G     +  +D  L        +     T+G+      FPRREF+  +
Sbjct: 358 STQCSIQIRLPNGQQLRKKLDNDTTLGRLWLIVIEEAEAQTHGHSGFMQPFPRREFSAAE 179

Query: 374 YKRRLLDLELAPSASVVL 391
             + L  L L PS S+VL
Sbjct: 178 MNKTLQQLGLVPSGSLVL 125
>02083
          Length = 1033

 Score = 31.2 bits (69), Expect = 0.92,   Method: Compositional matrix adjust.
 Identities = 15/37 (40%), Positives = 20/37 (54%)
 Frame = -3

Query: 355 YGNFSLATMFPRREFTREDYKRRLLDLELAPSASVVL 391
           Y    +   FPRREF+  +  + L  L L PS S+VL
Sbjct: 236 YAALLVTQPFPRREFSAAEMNKTLQQLGLVPSGSLVL 126
>20041
          Length = 535

 Score = 31.2 bits (69), Expect = 0.94,   Method: Compositional matrix adjust.
 Identities = 20/62 (32%), Positives = 27/62 (43%)
 Frame = +1

Query: 310 TARDRSTIARIQFRLPDGSSFTNQFPSDAPLEEARQFAAQTVGNTYGNFSLATMFPRREF 369
           T R  S  AR+Q  +  GS F  Q      ++  R+    T   T  NF++ TM   RE 
Sbjct: 343 TKRQLSNKARVQPIISQGSQFKGQSEESGTVDRGRKMDRYTWQKTNQNFNVQTMMGAREG 522

Query: 370 TR 371
            R
Sbjct: 523 RR 528
>11347
          Length = 961

 Score = 29.6 bits (65), Expect = 3.2,   Method: Compositional matrix adjust.
 Identities = 18/46 (39%), Positives = 23/46 (50%)
 Frame = -1

Query: 376 RRLLDLELAPSASVVLLPAGRPATSIVHSSSGDIWTLLGTVLYPFL 421
           R LL  +  P A +VLL    PA  + +SSS D W   G  L+ F 
Sbjct: 898 RALLF*QSFPKAFLVLLNP*MPANGLFYSSSKD*WCYGGACLHFFF 761
>06341
          Length = 818

 Score = 29.3 bits (64), Expect = 3.5,   Method: Compositional matrix adjust.
 Identities = 15/41 (36%), Positives = 22/41 (53%), Gaps = 7/41 (17%)
 Frame = +2

Query: 385 PSASVVLLPAG-------RPATSIVHSSSGDIWTLLGTVLY 418
           PS +++L PAG       RP +    S++ D W LLG + Y
Sbjct: 119 PSKALLLHPAGGLGGLRPRPPSEFFSSNNADAWLLLGLIYY 241
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|38089858|ref|XP_287905.2| PREDICTED:
hyperpolarization-activated, cyclic nucleotide-gated K+ 4 [Mus
musculus]
         (1201 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

18204                                                                  50   7e-06
08195                                                                  47   3e-05
27710                                                                  47   6e-05
19667                                                                  37   0.056
24780                                                                  35   0.14 
>18204
          Length = 429

 Score = 49.7 bits (117), Expect = 7e-06,   Method: Compositional matrix adjust.
 Identities = 36/104 (34%), Positives = 49/104 (47%), Gaps = 6/104 (5%)
 Frame = -1

Query: 578 REEIINFNCRKLVASMPLFANADPNFVTSMLTKLRFEVFQPGDYIIREGTIGKKMYFIQH 637
           REE I F     + S+ +  +   + +  +   L  + F  G++IIREG  G   + I  
Sbjct: 297 REENIRF-----LKSVSVLRDLPSDKLAKIADVLEIDFFHEGEFIIREGCTGDTFFLINK 133

Query: 638 GVVSVL--TKGNKE----TKLADGSYFGEICLLTRGRRTASVRA 675
           G V V     G++E     KL  G YFGE  LL   RRTAS  A
Sbjct: 132 GEVRVTQTVAGHEEPQEIRKLKRGDYFGEKALLGEDRRTASCIA 1

 Score = 29.6 bits (65), Expect = 8.0,   Method: Compositional matrix adjust.
 Identities = 15/44 (34%), Positives = 25/44 (56%)
 Frame = -1

Query: 658 FGEICLLTRGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRR 701
           FGE+ +L    RTASV+A T  +++ L    F  ++ +  + RR
Sbjct: 426 FGELAILYNCTRTASVKAVTDVKVWVLDRQMFQAIMMKTGLQRR 295
>08195
          Length = 2165

 Score = 47.4 bits (111), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 31/123 (25%), Positives = 59/123 (47%), Gaps = 5/123 (4%)
 Frame = -3

Query: 589  LVASMPLFANADPNFVTSMLTKLRFEVFQPGDYIIREGTIGKKMYFIQHGVVSVLTKGNK 648
            +V ++ LF + DP  +  +L  +  +  QPG++II +G  G   Y I  G   +      
Sbjct: 1638 VVKNILLFRSLDPEQMQEVLDAMFEKSVQPGEHIIDQGDDGDNFYVIDSGTYDIYVDVEG 1459

Query: 649  ETKLA----DGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDNFNE-VLEEYPMMRRAF 703
            + KL     +  +FGE+ L+    R A++ A +   +++L    F   VL+     R+ +
Sbjct: 1458 QAKLVGNYDNSGFFGELALMYNMPRAATIIASSTGTIWALDRTTFRRIVLKTAFQKRKKY 1279

Query: 704  ETV 706
            E++
Sbjct: 1278 ESL 1270

 Score = 47.4 bits (111), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 34/116 (29%), Positives = 52/116 (44%), Gaps = 11/116 (9%)
 Frame = -3

Query: 589  LVASMPLFANADPNFVTSMLTKLRFEVFQPGDYIIREGTIGKKMYFIQHGVVSVLTKGNK 648
            L+ S+PL  + D     ++   L+   ++ G  II++G     MYF++ G V +    NK
Sbjct: 1272 LLESVPLLKSLDLYERMNVADALQTRTYEDGVQIIKQGDAADVMYFVESGQVRIAMT-NK 1096

Query: 649  E-----------TKLADGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDNFNEVL 693
            E           T L  G YFGE+ L+T   R AS  A    +   L V  F  ++
Sbjct: 1095 ESTDPSAGETDVTVLEKGGYFGELALITHQPRAASAYAQGTVKCAVLDVHAFERLM 928
>27710
          Length = 429

 Score = 46.6 bits (109), Expect = 6e-05,   Method: Composition-based stats.
 Identities = 26/90 (28%), Positives = 44/90 (48%)
 Frame = +2

Query: 622 IIREGTIGKKMYFIQHGVVSVLTKGNKETKLADGSYFGEICLLTRGRRTASVRADTYCRL 681
           II++G  G   Y I  G V V       T +++G  FGE+ L+    R A+VRA +  +L
Sbjct: 8   IIQQGDEGDNFYVIDVGEVDVFVNSELVTTISEGGSFGELALIYGTPRAATVRAKSDVKL 187

Query: 682 YSLSVDNFNEVLEEYPMMRRAFETVALDRL 711
           + +  D++  +L    + +R      L R+
Sbjct: 188 WGIDRDSYRRILMGSTIRKRKMYEEFLSRV 277
>19667
          Length = 442

 Score = 36.6 bits (83), Expect = 0.056,   Method: Composition-based stats.
 Identities = 25/93 (26%), Positives = 38/93 (40%), Gaps = 5/93 (5%)
 Frame = +3

Query: 616 FQPGDYIIREGTIGKKMYFIQHGVVSVLTKGNKETKLADGSYFG-----EICLLTRGRRT 670
           F PG+ +I +G   + +Y++  G + VL        L  G  FG     E  +   G   
Sbjct: 69  FGPGEVLIHKGDAIRNIYYVCSGSLEVLKDEQVVAILGKGDLFGSDIKFEDPVSISG--- 239

Query: 671 ASVRADTYCRLYSLSVDNFNEVLEEYPMMRRAF 703
             VR+  YC L  ++     E L+ YP     F
Sbjct: 240 GDVRSLAYCELLCINTQGLAECLQPYPDFSEKF 338
>24780
          Length = 572

 Score = 35.4 bits (80), Expect = 0.14,   Method: Composition-based stats.
 Identities = 14/30 (46%), Positives = 20/30 (66%)
 Frame = +3

Query: 668 RRTASVRADTYCRLYSLSVDNFNEVLEEYP 697
           RRTA VR+  Y  +++LS  +F E + EYP
Sbjct: 6   RRTADVRSSGYTNVFTLSKHDFEEAMNEYP 95
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|8393845|ref|NP_058598.1| nephrocystin 1 [Mus
musculus]
         (691 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

12324                                                                  49   7e-06
16716                                                                  44   3e-04
30740                                                                  42   0.001
20131                                                                  42   0.001
13664                                                                  40   0.004
13641                                                                  37   0.038
29636                                                                  36   0.066
29687                                                                  34   0.18 
15115                                                                  34   0.22 
17286                                                                  32   0.82 
26032                                                                  32   0.88 
18050                                                                  32   1.2  
11228                                                                  31   1.5  
36643                                                                  31   1.7  
08480                                                                  30   2.5  
>12324
          Length = 946

 Score = 48.9 bits (115), Expect = 7e-06,   Method: Compositional matrix adjust.
 Identities = 21/52 (40%), Positives = 33/52 (63%)
 Frame = +3

Query: 161 IALGDFAAQQTGDLTFKKGDVLHIIEKKPDGWWLAKDAEGVEGLIPRTYLEP 212
           +A+ D+ A++  +LTF +  V+++I K  DGWW     +GV GL P  Y+EP
Sbjct: 699 VAIYDYEAEKDDELTFSENSVIYVIRKNDDGWWEGV-MDGVTGLFPSNYVEP 851
>16716
          Length = 934

 Score = 43.5 bits (101), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 23/53 (43%), Positives = 27/53 (50%)
 Frame = -1

Query: 159 TYIALGDFAAQQTGDLTFKKGDVLHIIEKKPDGWWLAKDAEGVEGLIPRTYLE 211
           T IAL D+ A    +LTF   DV+  IE   DGWW      G  GL P  Y+E
Sbjct: 466 TAIALYDYQAADDDELTFDPDDVITDIEMIDDGWWRGS-CHGKNGLFPANYVE 311
>30740
          Length = 488

 Score = 41.6 bits (96), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 18/42 (42%), Positives = 24/42 (57%)
 Frame = +2

Query: 165 DFAAQQTGDLTFKKGDVLHIIEKKPDGWWLAKDAEGVEGLIP 206
           DF+ +   DL F KGD+L +I K  + WW A+D  G  G  P
Sbjct: 206 DFSGRDPEDLPFSKGDILELISKDEEEWWTARDKHGRVGQDP 331
>20131
          Length = 574

 Score = 41.6 bits (96), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 18/52 (34%), Positives = 32/52 (61%)
 Frame = -2

Query: 160 YIALGDFAAQQTGDLTFKKGDVLHIIEKKPDGWWLAKDAEGVEGLIPRTYLE 211
           Y+A+  + + +T DLTF +GD++ ++ KK + WW     E   G+ P TY++
Sbjct: 474 YVAMYSYVSGETADLTFNEGDMI-LVTKKDEDWWTGTLGEKT-GMFPSTYVK 325

 Score = 35.4 bits (80), Expect = 0.080,   Method: Compositional matrix adjust.
 Identities = 16/56 (28%), Positives = 29/56 (51%), Gaps = 4/56 (7%)
 Frame = -2

Query: 161 IALGDFAAQQTGDLTFKKGDVLHIIEKKPDGWWLAK-DAEGVE---GLIPRTYLEP 212
           + +  + A   G L+ + G+++H+ +K P GWW  +  A G     G  P  Y++P
Sbjct: 273 MVIAPYTATGNGQLSLEPGNLIHVRQKSPRGWWEGELQARGQRKKIGWFPADYVKP 106
>13664
          Length = 507

 Score = 39.7 bits (91), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 15/44 (34%), Positives = 28/44 (63%)
 Frame = +2

Query: 161 IALGDFAAQQTGDLTFKKGDVLHIIEKKPDGWWLAKDAEGVEGL 204
           +AL D+ AQ++ +LT   GDV+ ++ K  + WW+ +  +G +G 
Sbjct: 374 VALYDYKAQRSDELTILSGDVIMLLHKDSESWWMGELLDGQQGF 505
>13641
          Length = 2081

 Score = 36.6 bits (83), Expect = 0.038,   Method: Compositional matrix adjust.
 Identities = 21/53 (39%), Positives = 30/53 (56%), Gaps = 4/53 (7%)
 Frame = +2

Query: 163 LGDFAAQQTGDLTFKKGDVLHIIEKKPDGWWLA---KDAEGVEGLIP-RTYLE 211
           L D    +   L+F++GD+LHI+ ++   WW A    DA+   GLIP R Y E
Sbjct: 188 LDDNIPCKEAGLSFQQGDILHIVNQEDAIWWQAYKHGDAKKRAGLIPSRHYHE 346
>29636
          Length = 354

 Score = 35.8 bits (81), Expect = 0.066,   Method: Compositional matrix adjust.
 Identities = 22/60 (36%), Positives = 29/60 (48%), Gaps = 15/60 (25%)
 Frame = +1

Query: 174 LTFKKGDVLHIIEKKPDGWWLA----KDAEGVEGLIP-----------RTYLEPYNKEDK 218
           ++F KGD+LH I+     WW A    +DA  + GLIP           R  L   NKE+K
Sbjct: 139 ISFLKGDILHAIQLSDSNWWQAHREGEDAHMLAGLIPSKAFQEQRESVRQQLNAENKENK 318
>29687
          Length = 434

 Score = 34.3 bits (77), Expect = 0.18,   Method: Compositional matrix adjust.
 Identities = 14/50 (28%), Positives = 26/50 (52%)
 Frame = -2

Query: 162 ALGDFAAQQTGDLTFKKGDVLHIIEKKPDGWWLAKDAEGVEGLIPRTYLE 211
           AL D+ A++  +L+F KG ++  + ++  GWW        +   P  Y+E
Sbjct: 286 ALHDYNAKREDELSFCKGAIITNVSRQDGGWWRGDYGTKKQHWFPSNYVE 137
>15115
          Length = 443

 Score = 33.9 bits (76), Expect = 0.22,   Method: Composition-based stats.
 Identities = 15/46 (32%), Positives = 24/46 (52%), Gaps = 3/46 (6%)
 Frame = -2

Query: 169 QQTGD---LTFKKGDVLHIIEKKPDGWWLAKDAEGVEGLIPRTYLE 211
            Q GD   +TF   D++  I++  +GWW     +G  G+ P  Y+E
Sbjct: 433 HQAGDDTEITFDPDDIITNIDQIDEGWWQGFAPDGSYGMFPANYVE 296
>17286
          Length = 489

 Score = 32.0 bits (71), Expect = 0.82,   Method: Composition-based stats.
 Identities = 15/50 (30%), Positives = 27/50 (54%)
 Frame = +3

Query: 162 ALGDFAAQQTGDLTFKKGDVLHIIEKKPDGWWLAKDAEGVEGLIPRTYLE 211
           A+ DF  +  G+L F++GD++ +I +  + W+      G  G  P  Y+E
Sbjct: 36  AIYDFLPESDGELGFQEGDMITLISQVDENWF-EGSVHGKVGYFPINYVE 182
>26032
          Length = 465

 Score = 32.0 bits (71), Expect = 0.88,   Method: Composition-based stats.
 Identities = 14/54 (25%), Positives = 28/54 (51%)
 Frame = +2

Query: 165 DFAAQQTGDLTFKKGDVLHIIEKKPDGWWLAKDAEGVEGLIPRTYLEPYNKEDK 218
           DF      +L F+K D++ +I +K +  W+  +  G+ G  P  ++E  ++  K
Sbjct: 29  DFERHDDDELGFRKNDIITLISQKDEHCWIG-ELNGLRGWFPAKFVEVLDERSK 187
>18050
          Length = 448

 Score = 31.6 bits (70), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 17/55 (30%), Positives = 28/55 (50%), Gaps = 1/55 (1%)
 Frame = +3

Query: 161 IALGDFAAQQTGDLTFKKGDVLHIIEKKPDGWWLAKDA-EGVEGLIPRTYLEPYN 214
           IA   + + +   L  + GDV+++  K PDGW+  +   +G  G  P +Y E  N
Sbjct: 27  IAKHSYESDEPDVLQLELGDVVNVSRKLPDGWYQGERIRDGAVGWFPGSYTEELN 191
>11228
          Length = 2155

 Score = 31.2 bits (69), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 14/45 (31%), Positives = 25/45 (55%), Gaps = 1/45 (2%)
 Frame = -2

Query: 168  AQQTGDLTFKKGDVLHIIEKKPDGW-WLAKDAEGVEGLIPRTYLE 211
            A  + +L+F KGDV  +  +  DGW W+  +     GL+P  +++
Sbjct: 1638 ATDSDELSFCKGDVFVVQNEMEDGWLWVTCERTKESGLVPAPFVK 1504
>36643
          Length = 601

 Score = 30.8 bits (68), Expect = 1.7,   Method: Compositional matrix adjust.
 Identities = 23/75 (30%), Positives = 36/75 (48%), Gaps = 4/75 (5%)
 Frame = +1

Query: 145 QEQASPKQAETETVTYIALGDFAAQQTGDLTFKKGDVLHI----IEKKPDGWWLAKDAEG 200
           QE+ S  + ET+ V    L  F  Q   +L+F  G  L +    ++ +  GW LA    G
Sbjct: 151 QEEESWAKGETDHVVAQTLFSFTGQGEEELSFSAGQQLILAPKEVQPQVRGWLLA-SVGG 327

Query: 201 VEGLIPRTYLEPYNK 215
            +GL+P  Y++   K
Sbjct: 328 RKGLVPYNYIKILGK 372
>08480
          Length = 698

 Score = 30.4 bits (67), Expect = 2.5,   Method: Compositional matrix adjust.
 Identities = 16/39 (41%), Positives = 20/39 (51%), Gaps = 6/39 (15%)
 Frame = -1

Query: 174 LTFKKGDVLHIIEKKPDGWWLAK------DAEGVEGLIP 206
           L F  GD+LH+     D WW AK        EG+ G+IP
Sbjct: 389 LWFHYGDILHVTNASDDEWWQAKRILPDGKEEGM-GIIP 276
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|157951604|ref|NP_031624.2| CAP, adenylate
cyclase-associated protein 1 [Mus musculus]
         (474 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

26791                                                                  48   9e-06
31863                                                                  31   1.3  
11726                                                                  28   9.3  
>26791
          Length = 468

 Score = 47.8 bits (112), Expect = 9e-06,   Method: Composition-based stats.
 Identities = 22/61 (36%), Positives = 36/61 (59%)
 Frame = +3

Query: 43  VQAFDSLLANPVAEYLKMSKEIGGDVQKHAEMVHTGLKLERALLATASQCQQPAGNKLSD 102
           V  F+ ++A P+++YL +S +IGGDV +HA+ V      +   +  A+Q  QPA  K  +
Sbjct: 279 VAGFEDIMAGPLSQYLALSAKIGGDVAQHAQYVKAAFDAQLRYVTLATQIAQPAQPKQME 458

Query: 103 L 103
           L
Sbjct: 459 L 461
>31863
          Length = 880

 Score = 30.8 bits (68), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 14/33 (42%), Positives = 20/33 (60%)
 Frame = -1

Query: 36  SKGAVPYVQAFDSLLANPVAEYLKMSKEIGGDV 68
           SKG +P  +   SL+A PV +YL  +  + GDV
Sbjct: 787 SKGLIPRCRFLWSLMAVPVVKYLPHTSHL*GDV 689
>11726
          Length = 458

 Score = 27.7 bits (60), Expect = 9.3,   Method: Composition-based stats.
 Identities = 18/73 (24%), Positives = 31/73 (42%)
 Frame = +1

Query: 345 ELKQVAYIYKCVNTTLQIKGKINSITVDNCKKLGLVFDDVVGIVEIINSRDVKVQVMGKV 404
           +L  V  +YK VN  L        +  D  K++G V +D + ++E     +  + +   V
Sbjct: 76  QLLAVCNLYKNVNVNLG-----EGVDPDRSKRIGDVIEDTLKLLEFCGGPNAFINIKYMV 240

Query: 405 PTISINKTDGCHA 417
           PT   +   GC  
Sbjct: 241 PTYESSVFPGCQG 279
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|94366760|ref|XP_930393.2| PREDICTED: similar to
microtubule-associated protein 1 A isoform 3 [Mus musculus]
         (3013 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

20910                                                                  51   9e-06
31722                                                                  32   4.0  
>20910
          Length = 490

 Score = 50.8 bits (120), Expect = 9e-06,   Method: Compositional matrix adjust.
 Identities = 34/99 (34%), Positives = 55/99 (55%), Gaps = 6/99 (6%)
 Frame = +3

Query: 2921 FFRRVRASYYVVSGNDPANGEPSRAVLDALLEGKAQWGEN--LQVTLIPTHDTEVTREWY 2978
            FF+RVRA  YV+S ++P    P   VL+ L+E KA W ++   +VT+IPT++T + + W 
Sbjct: 33   FFKRVRAKNYVLSASNP---NPK--VLEMLIEAKATWDKSNEQEVTVIPTYETPILQHWL 197

Query: 2979 XXXXXXXXXLNVLVL--ASSSTVVMQD--ESFPACKIEF 3013
                       +++   AS  TV +QD  +S    ++EF
Sbjct: 198  AVHKEKLAESKIVITPAASRCTVRLQDHEDSCYTYRLEF 314
>31722
          Length = 349

 Score = 32.0 bits (71), Expect = 4.0,   Method: Composition-based stats.
 Identities = 18/44 (40%), Positives = 25/44 (56%)
 Frame = +2

Query: 1578 QKEKELERKSETLQQKDQILSEKAAVVQRDSVMHQKDEALDEEN 1621
            Q+  +L  K   LQQKD  L EK      D+V+H+KD  L E++
Sbjct: 140  QQSTQLHEKDTQLQQKDAALHEK------DTVIHEKDTQLHEKD 253
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|113680348|ref|NP_032010.2| fascin homolog 1, actin
bundling protein [Mus musculus]
         (493 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

32867                                                                  47   1e-05
28242                                                                  30   3.2  
>32867
          Length = 513

 Score = 47.4 bits (111), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 31/109 (28%), Positives = 51/109 (46%), Gaps = 3/109 (2%)
 Frame = +3

Query: 365 ASVETAGDSELFLMKLINRPIIVFRGEHGFIGCRKVTGT-LDANRSSYDVFQLE-FNDGA 422
           A+ E+  +   F   LINRPI+V + E GF+G R      L+ N+++Y+   +E    G 
Sbjct: 3   ATSESIEEITKFYFYLINRPILVLKCEQGFVGYRTPGNLKLECNKATYETILVERAQKGL 182

Query: 423 YNIKDSTGKYWXXXXXXXXXXXXXXXXXFFLEFCDYNKVALKV-GGRYL 470
            ++K   GK W                 FFLE  +  ++ ++   G+YL
Sbjct: 183 VHLKAHRGKXWRIDGESISVDADAPTDGFFLELREPTRICIRSQKGKYL 329
>28242
          Length = 685

 Score = 29.6 bits (65), Expect = 3.2,   Method: Compositional matrix adjust.
 Identities = 28/97 (28%), Positives = 41/97 (42%), Gaps = 7/97 (7%)
 Frame = -3

Query: 100 RWSLQSEAHRRYFG-GTEDRLSCFAQSVSPAEKWSVHIAMHPQVNIYSVTRKRYAHLSAR 158
           RWSL+S  HR +   GT+D      Q + P+ +W   +    Q      TR   A LS +
Sbjct: 353 RWSLESTVHR*HLS*GTKDSRKTGKQQIIPSVRWRSTMKGEAQ----QTTRIPLA-LSLK 189

Query: 159 PADEI------AVDRDVPWGVDSLITLAFQDQRYSVQ 189
           P  ++       V R +P  V  L  L  + +R   Q
Sbjct: 188 PNQQLL*AATQPVHRLLPPTVTPLWQLRLRKRRGPAQ 78
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|160333789|ref|NP_035597.2| sepiapterin reductase [Mus
musculus]
         (262 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

30783                                                                  46   1e-05
23588                                                                  42   3e-04
12758                                                                  37   0.006
05690                                                                  37   0.010
12867                                                                  34   0.075
11922                                                                  28   2.8  
36857                                                                  28   3.5  
28229                                                                  27   6.2  
>30783
          Length = 765

 Score = 46.2 bits (108), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 30/84 (35%), Positives = 41/84 (48%), Gaps = 2/84 (2%)
 Frame = +1

Query: 153 VVNISSLCALQPYKGWGLYCAGKAARDMLYQVLAAE--EPSVRVLSYAPGPLDNDMQQLA 210
           +VN+SS+CA +P    G+YC  KAA DM  Q LA E     VRV S  PG + + + +  
Sbjct: 187 IVNVSSICASRPMAEVGVYCMSKAAMDMFTQCLALELAPHGVRVNSVNPGSVVSMIYRRG 366

Query: 211 RETSKDPELRSKLQKLKSDGALVD 234
                D +    L+  K    L D
Sbjct: 367 PSGYNDEDYAKFLESQKGKHPLGD 438
>23588
          Length = 611

 Score = 41.6 bits (96), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 44/152 (28%), Positives = 72/152 (47%)
 Frame = +3

Query: 64  VVLAAADLGTEAGVQRLLSAVRELPRPEGLQRLLLINNAATLGDVSKGFLNVNDLAEVNN 123
           VV  A DL  E   Q+L+++  +    +  Q  +L+NNA   G  + G L+   +  + N
Sbjct: 129 VVTVAGDLTDETFRQQLVASTVD----KFGQIDVLVNNA---GFANPGLLSBPGMENLLN 287

Query: 124 YWALNLTSMLCLTSGTLNAFQDSPGLSKTVVNISSLCALQPYKGWGLYCAGKAARDMLYQ 183
            ++LNL + + ++   +     S G    +VNISS  +++P    G YC  K       +
Sbjct: 288 VFSLNLNAHVAMSKLCVPHLLQSKG---NIVNISSNLSMRPSPALGAYCMSKRHWTCFTR 458

Query: 184 VLAAEEPSVRVLSYAPGPLDNDMQQLARETSK 215
           VLA E    R  S    P    M+++ R+TSK
Sbjct: 459 VLAYELAPKRSSSELGKP---RMREI-RDTSK 542
>12758
          Length = 804

 Score = 37.4 bits (85), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 40/155 (25%), Positives = 71/155 (45%), Gaps = 2/155 (1%)
 Frame = -1

Query: 56  GAQQPDLKVVLAAADLGTEAGVQRLLSAVRELPRPEGLQRLLLINNAATLGDVSKGFLNV 115
           G Q+P    +L   DL  E   +R+   V E  +  G  RL ++ N A  G +  G +  
Sbjct: 747 GGQKP----LLLVGDLTKEDDTKRV---VEETVKQFG--RLNILVNCA--GIIELGNIEN 601

Query: 116 NDLAEVNNYWALNLTSMLCLTSGTLNAFQDSPGLSKTVVNISSLCALQPYKGWGLYCAGK 175
             L + +  +  N+ S+  LT   +    ++ G    +VN+SS+  ++ +     YC  K
Sbjct: 600 TSLDQYDRMFNTNVRSVYHLTMLAVPHLVNTQG---NIVNVSSVNGMRSFPNVLAYCMAK 430

Query: 176 AARDMLYQVLAAE--EPSVRVLSYAPGPLDNDMQQ 208
           +A D   + +A E     VRV    PG + +++Q+
Sbjct: 429 SAIDQFTRCVALELAPKKVRVNGVNPGVIISELQK 325
>05690
          Length = 1192

 Score = 36.6 bits (83), Expect = 0.010,   Method: Compositional matrix adjust.
 Identities = 56/223 (25%), Positives = 93/223 (41%), Gaps = 8/223 (3%)
 Frame = +2

Query: 13  LTGASRGFGRALAPQLARL---LSPGSVMLVSARSESMLRQLKEELGAQQPD---LKVVL 66
           +TG   G G  LA  L +L   +  G +       +++  +  + L     D   L++V 
Sbjct: 188 ITGCDAGLGHLLAIHLDKLGVKVFAGCLFPGGEGEQTLKAKCSQRLCTVPLDVCSLEIVT 367

Query: 67  AAADLGTEAGVQRLLSAVRELPRPEGLQRLLLINNAATLGDVSKGFLNVNDLAEVNNYWA 126
            AAD           +  REL   +G +   ++NNA   G +  G L V   A+V+    
Sbjct: 368 TAAD-----------TVKREL---DGQELWGVVNNA---GIMHIGCLEVMGQADVDKILD 496

Query: 127 LNLTSMLCLTSGTLNAFQDSPGLSKTVVNISSLCALQPYKGWGLYCAGKAARDMLYQVLA 186
           +N    + +    L   + S G    +VN++S   + P     +YCA KAA   L + L 
Sbjct: 497 VNYRGQVNVIRAFLPFLRRSRG---RLVNVASNTGIAPVPYHAVYCASKAAVAALTESLR 667

Query: 187 AE-EP-SVRVLSYAPGPLDNDMQQLARETSKDPELRSKLQKLK 227
            E +P  VRV +  P      +QQ   +T+ D       Q+++
Sbjct: 668 LELQPFGVRVSTIIPSGYRTGIQQHNTQTTGDKWWAQAKQEVR 796
>12867
          Length = 858

 Score = 33.9 bits (76), Expect = 0.075,   Method: Compositional matrix adjust.
 Identities = 22/90 (24%), Positives = 37/90 (41%)
 Frame = -3

Query: 117 DLAEVNNYWALNLTSMLCLTSGTLNAFQDSPGLSKTVVNISSLCALQPYKGWGLYCAGKA 176
           DL E++ +  +NL+ ++      +  + +  G    +   SS+    P      YCA K 
Sbjct: 637 DLFELDVFAVVNLSRLV------VRYYLEQNGGRGHIAATSSIAGFSPVPFSATYCAAKH 476

Query: 177 ARDMLYQVLAAEEPSVRVLSYAPGPLDNDM 206
           A +     L  E   + V  +APGP   D 
Sbjct: 475 ALNAYLMSLKMEHRKLDVTIFAPGPTATDF 386
>11922
          Length = 2153

 Score = 28.5 bits (62), Expect = 2.8,   Method: Compositional matrix adjust.
 Identities = 13/32 (40%), Positives = 25/32 (78%)
 Frame = +1

Query: 13  LTGASRGFGRALAPQLARLLSPGSVMLVSARS 44
           +TGASRG G+A+A +LA+    G+ ++++A++
Sbjct: 115 ITGASRGIGKAIAVKLAK---DGANIVIAAKT 201
>36857
          Length = 697

 Score = 28.1 bits (61), Expect = 3.5,   Method: Compositional matrix adjust.
 Identities = 22/80 (27%), Positives = 38/80 (47%), Gaps = 5/80 (6%)
 Frame = +3

Query: 152 TVVNISSLCALQPYKGWGLYCAGKAARDMLYQVLAAE----EPSVRVLSYAPGPLDNDM- 206
           +++NISS   L+P     +YC  KA   M  + +AA     +  +RV +  P  +D  + 
Sbjct: 264 SIINISSAGGLRPQPVGPVYCGTKAGVMMFSRSVAAHKDYIDNGIRVNTLCPAFVDTPLV 443

Query: 207 QQLARETSKDPELRSKLQKL 226
            +LA   S D      L+++
Sbjct: 444 AKLASGLSDDTAAAKSLEEI 503
>28229
          Length = 633

 Score = 27.3 bits (59), Expect = 6.2,   Method: Compositional matrix adjust.
 Identities = 22/66 (33%), Positives = 32/66 (48%), Gaps = 5/66 (7%)
 Frame = -1

Query: 147 PGLSKT---VVNISSLCALQPYKGWGLYCAGKAARDMLYQVLAAE--EPSVRVLSYAPGP 201
           P L KT   VVN+SS   +  + G   Y   KAA D   ++++ E     VRV S  PG 
Sbjct: 294 PHLLKTKGAVVNVSSCAGICHFPGALSYGISKAALDQFTKIVSLELAPQGVRVNSVNPGF 115

Query: 202 LDNDMQ 207
           +  ++ 
Sbjct: 114 VVTNIH 97
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|19549320|ref|NP_084482.1| cytoglobin [Mus musculus]
         (190 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

37114                                                                  45   1e-05
23395                                                                  27   4.2  
>37114
          Length = 493

 Score = 45.4 bits (106), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 20/60 (33%), Positives = 37/60 (61%)
 Frame = -1

Query: 26  AVQATWARLYANCEDVGVAILVRFFVNFPSAKQYFSQFRHMEDPLEMERSPQLRKHACRV 85
           A++ +W+ L  +    G A+++RFF  +P  +QYF++FR +    ++  S  L++HA RV
Sbjct: 244 AIRQSWSLLAPHSTQHGTALMIRFFEXYPHNQQYFAEFRDVS-AQDLRHSAGLQQHAVRV 68
>23395
          Length = 1060

 Score = 27.3 bits (59), Expect = 4.2,   Method: Compositional matrix adjust.
 Identities = 15/45 (33%), Positives = 22/45 (48%)
 Frame = -3

Query: 44  AILVRFFVNFPSAKQYFSQFRHMEDPLEMERSPQLRKHACRVMGA 88
           A L + FVN P A    S+ + + + L   R P L KH+ +  G 
Sbjct: 974 AGLTKDFVNLPPAPLQASRLQELSEHLPSLRRPSLVKHSTKHHGG 840
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|27229077|ref|NP_081068.1| 1-acylglycerolphosphate
acyltransferase-epsilon [Mus musculus]
         (365 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

27346                                                                  47   1e-05
34413                                                                  28   7.7  
>27346
          Length = 790

 Score = 46.6 bits (109), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 40/141 (28%), Positives = 58/141 (41%), Gaps = 27/141 (19%)
 Frame = +1

Query: 183 KLLSASQAFAAQRGLAVLKHVLTPRIKATHVAFDSMKS---------------------- 220
           K L +SQ +A + G  VL +V  PRI A  +  D++ S                      
Sbjct: 103 KRLESSQNYARKYGYPVLNNVTLPRIGALTLIIDTVGSVEQGETLDNGYNDGKTDTHDPD 282

Query: 221 -HLDAIYDVTVVYEGNEKGSGKYSNPPSM----TEFLCKQCPKLHIHFDRIDRNEVPEEQ 275
             L  I D+T+ Y   E        PP M      +  KQ   +H+H+     +EVP + 
Sbjct: 283 HPLKWIVDMTIGYRNKE------GEPPDMLGMCVGYRVKQ--DVHVHYRAYPLSEVPRDX 438

Query: 276 EHMKKWLHERFEIKDRLLIEF 296
           E   KW ++R+  KD LL  F
Sbjct: 439 EEQLKWFYDRYAEKDTLLDYF 501
>34413
          Length = 475

 Score = 27.7 bits (60), Expect = 7.7,   Method: Compositional matrix adjust.
 Identities = 20/64 (31%), Positives = 27/64 (42%)
 Frame = -3

Query: 134 AQHGGIYVKRSAKFNDKEMRSKLQSYVNAGTPMYLVIFPEGTRYNATYTKLLSASQAFAA 193
           AQ GG+  ++  K    E RSK         PMYLVI    +    +YT  +    +F  
Sbjct: 362 AQDGGLADEKKGKAAPSE-RSKFFDLSLLSDPMYLVILISNSTNAISYTNFIILLPSFGL 186

Query: 194 QRGL 197
            RG 
Sbjct: 185 DRGF 174
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|27229278|ref|NP_443747.2| 1-acylglycerol-3-phosphate
O-acyltransferase 3 [Mus musculus]
         (376 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

27346                                                                  47   1e-05
20188                                                                  29   3.3  
>27346
          Length = 790

 Score = 47.0 bits (110), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 24/75 (32%), Positives = 40/75 (53%), Gaps = 4/75 (5%)
 Frame = +1

Query: 225 IYDVTLNFRGNKN--PSLLGILYGKKYEADMCV--RRFPLEDIPADETSAAQWLHKLYQE 280
           I D+T+ +R  +   P +LG+  G + + D+ V  R +PL ++P D     +W +  Y E
Sbjct: 298 IVDMTIGYRNKEGEPPDMLGMCVGYRVKQDVHVHYRAYPLSEVPRDXEEQLKWFYDRYAE 477

Query: 281 KDALQEMYKQKGVFP 295
           KD L + +   G FP
Sbjct: 478 KDTLLDYFNTHGHFP 522
>20188
          Length = 487

 Score = 28.9 bits (63), Expect = 3.3,   Method: Compositional matrix adjust.
 Identities = 10/32 (31%), Positives = 17/32 (53%)
 Frame = -1

Query: 13  VHLLIGFVFVVSGLIINFTQLCTLALWPISKH 44
           +HL +G++F    + +N    CT+   P S H
Sbjct: 460 IHLFLGYIFSTDNIFLNNIHECTIHSIPQSDH 365
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31560239|ref|NP_079886.2| asparaginase like 1 [Mus
musculus]
         (326 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

14769                                                                  47   1e-05
>14769
          Length = 1139

 Score = 46.6 bits (109), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 31/75 (41%), Positives = 44/75 (58%), Gaps = 5/75 (6%)
 Frame = -3

Query: 180 PKNSGTVGAVALDCRGNLAYATSTGGIVNKMVGRVGDSPCIGAGGYA---DNNLGAVS-- 234
           P    TVGAV +D  G+++ A S+GGI  K  GR+G +   GAG +A   D+ L AV   
Sbjct: 681 PAAQDTVGAVCVDWHGDVSAAVSSGGIWLKQPGRLGPAAMYGAGCWAQNGDDQLPAVGVI 502

Query: 235 TTGHGESILKVNLAR 249
           T+G GE + +  LA+
Sbjct: 501 TSGCGEHVTRTLLAK 457

 Score = 28.1 bits (61), Expect = 4.6,   Method: Compositional matrix adjust.
 Identities = 20/66 (30%), Positives = 30/66 (45%), Gaps = 10/66 (15%)
 Frame = -3

Query: 93   EMDASIMDGKDLSAGAVSAVRCIANPVKLARLVME----------KTPHCFLTGHGAEKF 142
            E DAS+M+G     G    V  + NPV+LA  +++          + P   L G GA  +
Sbjct: 1137 ECDASVMEGAGALFGGAGCVSGVRNPVQLASHLLQAQQHTTLSLGRVPPSVLVGPGAADW 958

Query: 143  AEDMGI 148
            A   G+
Sbjct: 957  ARQQGM 940
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|33147082|ref|NP_476512.1| HLA-B-associated transcript
3 [Mus musculus]
         (1154 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

13455                                                                  49   1e-05
08296                                                                  47   3e-05
04017                                                                  47   5e-05
00758                                                                  47   5e-05
04649                                                                  46   8e-05
03942                                                                  45   2e-04
24173                                                                  42   0.002
34270                                                                  38   0.026
21766                                                                  38   0.030
02863                                                                  32   1.9  
06586                                                                  31   3.2  
>13455
          Length = 809

 Score = 48.5 bits (114), Expect = 1e-05,   Method: Composition-based stats.
 Identities = 26/73 (35%), Positives = 42/73 (57%), Gaps = 1/73 (1%)
 Frame = +3

Query: 16  SLEVLVKTLDSQTRTFIVGAQMNVKEFKEHIAASVSIPSEKQRLIYQGRVLQDDKKLQEY 75
           S+++ VKTL  +T T  V     ++  K  I     IP ++QRLI+ G+ L+D + L +Y
Sbjct: 354 SMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDY 533

Query: 76  NVGGK-VIHLVER 87
           N+  +  +HLV R
Sbjct: 534 NIQKESTLHLVLR 572
>08296
          Length = 897

 Score = 47.4 bits (111), Expect = 3e-05,   Method: Composition-based stats.
 Identities = 25/72 (34%), Positives = 40/72 (55%), Gaps = 1/72 (1%)
 Frame = +1

Query: 15  DSLEVLVKTLDSQTRTFIVGAQMNVKEFKEHIAASVSIPSEKQRLIYQGRVLQDDKKLQE 74
           + + + VKTL  +     +     V+  KE +     IP ++QRLI+ G+ + D+K  Q+
Sbjct: 121 NKMLIKVKTLTGKEIEIDIEPTDKVERIKERVEEKEGIPPQQQRLIFSGKQMNDEKTAQD 300

Query: 75  YNV-GGKVIHLV 85
           Y V GG V+HLV
Sbjct: 301 YKVIGGSVLHLV 336
>04017
          Length = 690

 Score = 47.0 bits (110), Expect = 5e-05,   Method: Composition-based stats.
 Identities = 25/72 (34%), Positives = 41/72 (56%), Gaps = 1/72 (1%)
 Frame = -1

Query: 17  LEVLVKTLDSQTRTFIVGAQMNVKEFKEHIAASVSIPSEKQRLIYQGRVLQDDKKLQEYN 76
           +++ VKTL  +T T  V     ++  K  I     IP ++QRLI+ G+ L+D + L +YN
Sbjct: 342 MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYN 163

Query: 77  VGGK-VIHLVER 87
           +  +  +HLV R
Sbjct: 162 IQKESTLHLVLR 127
>00758
          Length = 1050

 Score = 47.0 bits (110), Expect = 5e-05,   Method: Composition-based stats.
 Identities = 25/72 (34%), Positives = 41/72 (56%), Gaps = 1/72 (1%)
 Frame = +1

Query: 17  LEVLVKTLDSQTRTFIVGAQMNVKEFKEHIAASVSIPSEKQRLIYQGRVLQDDKKLQEYN 76
           +++ VKTL  +T T  V     ++  K  I     IP ++QRLI+ G+ L+D + L +YN
Sbjct: 523 MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYN 702

Query: 77  VGGK-VIHLVER 87
           +  +  +HLV R
Sbjct: 703 IQKESTLHLVLR 738
>04649
          Length = 1590

 Score = 46.2 bits (108), Expect = 8e-05,   Method: Composition-based stats.
 Identities = 25/72 (34%), Positives = 41/72 (56%), Gaps = 1/72 (1%)
 Frame = -2

Query: 17  LEVLVKTLDSQTRTFIVGAQMNVKEFKEHIAASVSIPSEKQRLIYQGRVLQDDKKLQEYN 76
           +++ VKTL  +T T  V     ++  K  I     IP ++QRLI+ G+ L+D + L +YN
Sbjct: 449 MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYN 270

Query: 77  VGGK-VIHLVER 87
           +  +  +HLV R
Sbjct: 269 IQKESTLHLVLR 234
>03942
          Length = 912

 Score = 44.7 bits (104), Expect = 2e-04,   Method: Composition-based stats.
 Identities = 24/72 (33%), Positives = 40/72 (55%), Gaps = 1/72 (1%)
 Frame = +1

Query: 17  LEVLVKTLDSQTRTFIVGAQMNVKEFKEHIAASVSIPSEKQRLIYQGRVLQDDKKLQEYN 76
           +++ VKTL  +T T  V     ++  K        IP ++QRLI+ G+ L+D + L +YN
Sbjct: 406 MQIFVKTLTGKTITLEVEPSDTIENVKAKSKDKEGIPPDQQRLIFAGKQLEDGRTLSDYN 585

Query: 77  VGGK-VIHLVER 87
           +  +  +HLV R
Sbjct: 586 IQKESTLHLVLR 621
>24173
          Length = 413

 Score = 41.6 bits (96), Expect = 0.002,   Method: Composition-based stats.
 Identities = 29/84 (34%), Positives = 44/84 (52%), Gaps = 5/84 (5%)
 Frame = -2

Query: 9   TAMEE---PDSLEVLVKTLDSQTRTFIV-GAQMNVKEFKEHIAASVSIPSEKQRLIYQGR 64
           TA EE   P +  + +KTL  Q R+ +     + V E K  I     I  E+QRL++ G+
Sbjct: 382 TAQEEDTTPTAFSLNLKTLTRQERSALTWEGGVTVGELKCQIYDKDGISPEQQRLVFAGK 203

Query: 65  VLQDDKKLQEYNV-GGKVIHLVER 87
            L+D + L +YN+     +HLV R
Sbjct: 202 QLEDGRLLSDYNITDDSTLHLVFR 131
>34270
          Length = 274

 Score = 37.7 bits (86), Expect = 0.026,   Method: Composition-based stats.
 Identities = 20/58 (34%), Positives = 31/58 (53%)
 Frame = +1

Query: 20  LVKTLDSQTRTFIVGAQMNVKEFKEHIAASVSIPSEKQRLIYQGRVLQDDKKLQEYNV 77
           L  TL  +T T  V     ++  K  I     IP ++QRLI+ G+ L+D + L +YN+
Sbjct: 43  LSSTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNI 216
>21766
          Length = 417

 Score = 37.7 bits (86), Expect = 0.030,   Method: Compositional matrix adjust.
 Identities = 16/37 (43%), Positives = 22/37 (59%)
 Frame = +2

Query: 1043 IIQQDIQSQRKVKPQPPLSDAYLSGMPAKRRKTMQGE 1079
            +++ D+Q Q+    Q P SD YL G P KRR+ M  E
Sbjct: 113  VMEADVQRQKTQHSQAPFSDTYLQGXPPKRRRLMSYE 223
>02863
          Length = 583

 Score = 31.6 bits (70), Expect = 1.9,   Method: Composition-based stats.
 Identities = 20/59 (33%), Positives = 28/59 (47%), Gaps = 3/59 (5%)
 Frame = +1

Query: 9   TAMEE---PDSLEVLVKTLDSQTRTFIVGAQMNVKEFKEHIAASVSIPSEKQRLIYQGR 64
           TA EE   P +  + +KTL  +T        M V E K  I     I  E+QRL++ G+
Sbjct: 280 TAQEEDTTPTAFSLNLKTLTGKTVALTGEGGMTVGELKCQIYDKDGISPEQQRLVFAGK 456
>06586
          Length = 736

 Score = 30.8 bits (68), Expect = 3.2,   Method: Composition-based stats.
 Identities = 14/28 (50%), Positives = 19/28 (67%)
 Frame = +1

Query: 881 SGFGARLLELCNQGLFECLALNLHCLGG 908
           + FG +LLELCN  +F+C+ LN  C  G
Sbjct: 7   NAFGEQLLELCN--MFDCIILNGLCETG 84
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|33468857|ref|NP_032274.1| histidine triad nucleotide
binding protein 1 [Mus musculus]
         (126 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

15997                                                                  45   1e-05
03327                                                                  37   0.002
20597                                                                  27   2.1  
29242                                                                  26   5.2  
02200                                                                  26   5.4  
00931                                                                  25   7.9  
>15997
          Length = 652

 Score = 44.7 bits (104), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 32/100 (32%), Positives = 48/100 (48%), Gaps = 2/100 (2%)
 Frame = +2

Query: 26  EIPAKIIFEDDRCLAFHDISPQAPTHFLVIPKKHISQISVADDDDESLLGHLMIVGKKCA 85
           E   +++++ D  + F DI P A  H+LV+PK HI         D  LL  L+ VG +  
Sbjct: 185 ENSTRLLYDQDGIVIFKDIRPAASHHYLVVPKTHIKDAKHLTVKDTPLLEQLVKVGTEFL 364

Query: 86  ADL-GLKRGYRMVVNEGADGGQSVYHIHLHVLGGR-QMNW 123
               G  +  RM  +       SV H+HLHV+  + +M W
Sbjct: 365 QQQGGDDKNARMGFHWPP--FHSVAHLHLHVISPQSEMGW 478
>03327
          Length = 1281

 Score = 37.4 bits (85), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 25/85 (29%), Positives = 40/85 (47%), Gaps = 3/85 (3%)
 Frame = -3

Query: 38   CLAFHDISPQAPTHFLVI---PKKHISQISVADDDDESLLGHLMIVGKKCAADLGLKRGY 94
              AF +I P  P H L+    P +H+S ++ A+  D   L  L+        +       
Sbjct: 1072 SFAFVNIKPVLPGHMLIASLRPVEHMSDLTQAEVSD---LFTLVQRVSDVTQNKFEASSV 902

Query: 95   RMVVNEGADGGQSVYHIHLHVLGGR 119
             + V +G D GQ+V H+H+H+L  R
Sbjct: 901  TIAVQDGPDAGQTVKHVHVHILPRR 827
>20597
          Length = 1474

 Score = 26.9 bits (58), Expect = 2.1,   Method: Composition-based stats.
 Identities = 10/22 (45%), Positives = 16/22 (72%)
 Frame = -2

Query: 44  ISPQAPTHFLVIPKKHISQISV 65
           +SP APTHF V P+ + + +S+
Sbjct: 825 LSPLAPTHFKVSPEHYCTLVSL 760
>29242
          Length = 316

 Score = 25.8 bits (55), Expect = 5.2,   Method: Compositional matrix adjust.
 Identities = 14/32 (43%), Positives = 19/32 (59%)
 Frame = -1

Query: 42  HDISPQAPTHFLVIPKKHISQISVADDDDESL 73
           HD + QAP      P+K I ++  AD +DESL
Sbjct: 157 HDANYQAP------PEKTIEELMAADQEDESL 80
>02200
          Length = 2191

 Score = 25.8 bits (55), Expect = 5.4,   Method: Composition-based stats.
 Identities = 10/28 (35%), Positives = 14/28 (50%)
 Frame = +1

Query: 25  KEIPAKIIFEDDRCLAFHDISPQAPTHF 52
           KE  + +++    CL  HD    AP HF
Sbjct: 796 KETASSLLYMPMECLTQHDCEVNAPAHF 879
>00931
          Length = 2687

 Score = 25.0 bits (53), Expect = 7.9,   Method: Composition-based stats.
 Identities = 11/20 (55%), Positives = 11/20 (55%)
 Frame = +1

Query: 97   VVNEGADGGQSVYHIHLHVL 116
            V   GA  G  V HIH HVL
Sbjct: 1231 VAQRGAASGPDVLHIHAHVL 1290
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|38084010|ref|XP_140391.3| PREDICTED: WD repeat domain
7 isoform 1 [Mus musculus]
         (1489 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

30256                                                                  49   1e-05
01249                                                                  42   0.002
13335                                                                  42   0.002
17598                                                                  42   0.003
19949                                                                  41   0.005
17266                                                                  40   0.005
13278                                                                  40   0.007
27270                                                                  38   0.026
12806                                                                  38   0.035
02147                                                                  38   0.040
29912                                                                  37   0.051
27806                                                                  35   0.20 
01327                                                                  34   0.38 
34005                                                                  34   0.45 
19863                                                                  33   0.68 
03387                                                                  33   0.71 
15780                                                                  33   0.77 
27465                                                                  33   0.78 
03395                                                                  33   1.00 
15118                                                                  33   1.1  
12960                                                                  32   1.4  
28151                                                                  32   1.9  
21921                                                                  32   2.2  
12574                                                                  32   2.3  
14124                                                                  32   2.4  
19498                                                                  32   2.5  
18981                                                                  32   2.6  
26939                                                                  31   3.2  
00561                                                                  31   3.6  
01462                                                                  31   3.9  
34541                                                                  31   4.0  
21513                                                                  31   4.1  
13412                                                                  30   5.1  
10162                                                                  30   6.3  
17602                                                                  30   6.5  
14500                                                                  30   7.7  
02090                                                                  30   8.7  
>30256
          Length = 961

 Score = 49.3 bits (116), Expect = 1e-05,   Method: Composition-based stats.
 Identities = 38/154 (24%), Positives = 71/154 (46%), Gaps = 9/154 (5%)
 Frame = +3

Query: 452 RGWPPH-----RTLRGHRNKVTCLLYPHQVSARYDQRYLISGGVDFSVIIWDIFSGEMKH 506
           R W P       TL+GH N+V  L        ++D  Y++SG +D S+ +WD+  G++ H
Sbjct: 351 RVWDPDTASCLHTLQGHTNRVYSL--------QFDGVYVVSGSLDTSIRVWDVRCGKLVH 506

Query: 507 IFCVHGGEITQLLVPPENCSARVQHCICSVASDHSVGLLSLREKKCIML---ASRHLFPI 563
               H    + L +          + + S  +D +V +  +   KC+      ++H   +
Sbjct: 507 TLMGHQSLTSGLELK--------DNLLVSGNADSTVKVWDVHTGKCLQTLLGPNKHRSAV 662

Query: 564 QVIKWRPSDDYLVVGCT-DGSVYVWQMDTGALDR 596
             +++   +   VV C+ DG+V +W ++TG   R
Sbjct: 663 TCLQF---NKKFVVTCSDDGTVKLWDLNTGDFIR 755

 Score = 40.4 bits (93), Expect = 0.005,   Method: Composition-based stats.
 Identities = 21/72 (29%), Positives = 39/72 (54%)
 Frame = +3

Query: 31  GGTIVTGCHDGQICLWDVSVELEVNPRALLFGHTASITCLSKACASGDKRYTVSASANGE 90
           G T+++G  D  + +W+    +  +    L+GH++++ CLS    SG K   VS S +  
Sbjct: 72  GNTVISGSTDRSLKVWNADTGVCTHT---LYGHSSTVRCLS---LSGKK--VVSGSRDAT 227

Query: 91  MCLWDVNDGRCI 102
           + +WD+  G C+
Sbjct: 228 LRVWDIESGHCL 263

 Score = 38.9 bits (89), Expect = 0.018,   Method: Composition-based stats.
 Identities = 34/142 (23%), Positives = 56/142 (39%)
 Frame = +3

Query: 459 TLRGHRNKVTCLLYPHQVSARYDQRYLISGGVDFSVIIWDIFSGEMKHIFCVHGGEITQL 518
           TL GH + V CL            + ++SG  D ++ +WDI SG   ++   H   +   
Sbjct: 147 TLYGHSSTVRCL--------SLSGKKVVSGSRDATLRVWDIESGHCLNVLLGHMAAV--- 293

Query: 519 LVPPENCSARVQHCICSVASDHSVGLLSLREKKCIMLASRHLFPIQVIKWRPSDDYLVVG 578
                 C       + S A D++V +       C+     H   +  +++     Y+V G
Sbjct: 294 -----RCVQYDGKRVVSGAXDYTVRVWDPDTASCLHTLQGHTNRVYSLQF--DGVYVVSG 452

Query: 579 CTDGSVYVWQMDTGALDRCAMG 600
             D S+ VW +  G L    MG
Sbjct: 453 SLDTSIRVWDVRCGKLVHTLMG 518

 Score = 33.1 bits (74), Expect = 0.87,   Method: Composition-based stats.
 Identities = 22/74 (29%), Positives = 36/74 (48%)
 Frame = +3

Query: 30  DGGTIVTGCHDGQICLWDVSVELEVNPRALLFGHTASITCLSKACASGDKRYTVSASANG 89
           DG  +V+G  D  I +WDV     V+    L GH +  + L            VS +A+ 
Sbjct: 429 DGVYVVSGSLDTSIRVWDVRCGKLVHT---LMGHQSLTSGLEL-----KDNLLVSGNADS 584

Query: 90  EMCLWDVNDGRCIE 103
            + +WDV+ G+C++
Sbjct: 585 TVKVWDVHTGKCLQ 626

 Score = 31.6 bits (70), Expect = 2.8,   Method: Composition-based stats.
 Identities = 23/117 (19%), Positives = 49/117 (41%)
 Frame = +3

Query: 477 SARYDQRYLISGGVDFSVIIWDIFSGEMKHIFCVHGGEITQLLVPPENCSARVQHCICSV 536
           S++     +ISG  D S+ +W+  +G   H    H   +         C +     + S 
Sbjct: 57  SSQMTGNTVISGSTDRSLKVWNADTGVCTHTLYGHSSTV--------RCLSLSGKKVVSG 212

Query: 537 ASDHSVGLLSLREKKCIMLASRHLFPIQVIKWRPSDDYLVVGCTDGSVYVWQMDTGA 593
           + D ++ +  +    C+ +   H+  ++ +++      +V G  D +V VW  DT +
Sbjct: 213 SRDATLRVWDIESGHCLNVLLGHMAAVRCVQY--DGKRVVSGAXDYTVRVWDPDTAS 377
>01249
          Length = 1743

 Score = 42.0 bits (97), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 29/103 (28%), Positives = 51/103 (49%), Gaps = 1/103 (0%)
 Frame = -1

Query: 421  LVCGREDGSIIIVPA-TQTAIVQLLQGEHMLRRGWPPHRTLRGHRNKVTCLLYPHQVSAR 479
            L+ G ++G I+  P   Q +  ++   +H  + G    R L+GH + VTCL +       
Sbjct: 1038 LLAGLDNGDILCSPLFGQISQSEVFVSKHTTKAG---ERVLQGHSDAVTCLAF------S 886

Query: 480  YDQRYLISGGVDFSVIIWDIFSGEMKHIFCVHGGEITQLLVPP 522
             D + L SG  +  VIIW++ SG+   +  + G     +++PP
Sbjct: 885  SDGQRLASGSQNGKVIIWNMESGDSTSLD-ISGAVGNVMIIPP 760

 Score = 34.7 bits (78), Expect = 0.31,   Method: Compositional matrix adjust.
 Identities = 37/150 (24%), Positives = 58/150 (38%), Gaps = 12/150 (8%)
 Frame = -1

Query: 1    MAGNSLVLPIVLWGRKAPTHCISSILLTDDGGTIVTGCHDGQICLWDVSVELE------- 53
            M G SLV      G  +  +  + I  TDDG   V     G + +WD +  +        
Sbjct: 1407 MTGGSLV------GLLSDFNEATKIQFTDDGSQFVVATSSGHLNIWDFARVVTTTSQRAR 1246

Query: 54   -VNPRALLFGHTASITCLSKACASGDKRYTVSASANGEMCLWDVNDGRCIEF----TKLA 108
             + P   +  H+  IT L   C  G      S+S++G   LWD+  G  +      T + 
Sbjct: 1245 GLKPGRTINAHSEPITGLHVGCG-GPAARVASSSSDGTCKLWDMLSGALLRTMVYETGVG 1069

Query: 109  CTHTGIQFYQFSVGNQQEGRLLCHGHYPEI 138
            C     Q + F +     G +LC   + +I
Sbjct: 1068 CLIMDKQEH-FLLAGLDNGDILCSPLFGQI 982

 Score = 30.8 bits (68), Expect = 4.0,   Method: Compositional matrix adjust.
 Identities = 22/72 (30%), Positives = 35/72 (48%), Gaps = 2/72 (2%)
 Frame = -1

Query: 30   DGGTIVTGCHDGQICLWDVSVELEVNPRA--LLFGHTASITCLSKACASGDKRYTVSASA 87
            D G I+     GQI   +V V          +L GH+ ++TCL+    S D +   S S 
Sbjct: 1023 DNGDILCSPLFGQISQSEVFVSKHTTKAGERVLQGHSDAVTCLA---FSSDGQRLASGSQ 853

Query: 88   NGEMCLWDVNDG 99
            NG++ +W++  G
Sbjct: 852  NGKVIIWNMESG 817

 Score = 29.6 bits (65), Expect = 8.7,   Method: Compositional matrix adjust.
 Identities = 26/114 (22%), Positives = 50/114 (43%)
 Frame = -1

Query: 1376 VALYDIRTGKCQTIHGHKGPITAVSFAPDGRYLATYSNTDSHISFWQMNTSLLGSIGMLN 1435
            V+ +  + G+ + + GH   +T ++F+ DG+ LA+ S  +  +  W M +    S+ +  
Sbjct: 963  VSKHTTKAGE-RVLQGHSDAVTCLAFSSDGQRLASGSQ-NGKVIIWNMESGDSTSLDISG 790

Query: 1436 SAPQLRCIKTYQVPPVQPASPGSHNALKLARLIWTSNRNVILMAHDGKEHRFMV 1489
            +   +  I     PP+  +S  +H    +      S +  I    DGK   F V
Sbjct: 789  AVGNVMII-----PPIVHSSTXAHQGPPI------SFKQHISREEDGKGRVFNV 661
>13335
          Length = 863

 Score = 42.0 bits (97), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 28/88 (31%), Positives = 43/88 (48%), Gaps = 1/88 (1%)
 Frame = +1

Query: 34  IVTGCHDGQICLWDVSVELEVNPRALLFGHTASITCLSKACASGDKRYTVSASANGEMCL 93
           +V+G  D  IC+W+V+ +  V       GH  S+  L+    S +  Y VS S NG++ +
Sbjct: 106 LVSGSDDDTICMWEVATQKLVRS---YVGHEDSVMALAY---SPNGHYLVSGSPNGDLYV 267

Query: 94  WDVNDGRCIEFTKLACTHT-GIQFYQFS 120
           WD + G C   T     H  G+   +FS
Sbjct: 268 WDASFGHCRHLTLRVDAHDLGVTCCEFS 351

 Score = 34.7 bits (78), Expect = 0.28,   Method: Compositional matrix adjust.
 Identities = 26/122 (21%), Positives = 53/122 (43%)
 Frame = +1

Query: 494 VIIWDIFSGEMKHIFCVHGGEITQLLVPPENCSARVQHCICSVASDHSVGLLSLREKKCI 553
           VI+WD+ +G +K  +  H  + +  +      S+     + S + D ++ +  +  +K +
Sbjct: 4   VIVWDVKTGSIKGEY-QHASKSSIRVCKFSPSSSH----LVSGSDDDTICMWEVATQKLV 168

Query: 554 MLASRHLFPIQVIKWRPSDDYLVVGCTDGSVYVWQMDTGALDRCAMGITAVEILNACDEA 613
                H   +  + + P+  YLV G  +G +YVW    G      + + A ++   C E 
Sbjct: 169 RSYVGHEDSVMALAYSPNGHYLVSGSPNGDLYVWDASFGHCRHLTLRVDAHDLGVTCCEF 348

Query: 614 VP 615
            P
Sbjct: 349 SP 354
>17598
          Length = 875

 Score = 41.6 bits (96), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 41/158 (25%), Positives = 71/158 (44%), Gaps = 7/158 (4%)
 Frame = +1

Query: 456 PHRTLRGHRNKVTCLLYPHQVSARYDQRYLISGGVDFSVIIWDIFSGEMKHIFCVHGGEI 515
           P RTL+GH + V+       VS   D RY++S   D ++ +WDI  G     F  H  + 
Sbjct: 97  PRRTLQGHSHFVS------DVSLSADSRYVLSSSWDATLRLWDIKKGNTTRRFISHTRDA 258

Query: 516 TQLLVPPENCSARVQHCICSVASDHSVGLL-SLREKKCIMLASRHLFPIQVIKW-RPSDD 573
             +   P+N        I S   D ++ +  ++ E K  + A+ H   +  +K+ + +  
Sbjct: 259 LAVAFSPDN------RQIASGGRDKALKIWNTVGECKFTVDANSHQDWVTCVKFHQDAKS 420

Query: 574 YLVVGCT-DGSVYVWQMDTGALDRCAMG----ITAVEI 606
            LVV  + D ++ VW   T  L    +G    I A+++
Sbjct: 421 PLVVSASMDKTIKVWDNQTMTLKHTFVGHKTQINAIDL 534
>19949
          Length = 903

 Score = 40.8 bits (94), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 22/62 (35%), Positives = 33/62 (53%), Gaps = 1/62 (1%)
 Frame = +2

Query: 1368 AVGARHGSVALYDIRTGKC-QTIHGHKGPITAVSFAPDGRYLATYSNTDSHISFWQMNTS 1426
            A G+   +V L+DIR   C  T  GH G +  + F+PDGR++A+ S  D  +  W +   
Sbjct: 41   ASGSMDCNVKLWDIRRKGCIYTYKGHTGCVCCLRFSPDGRWIASASE-DGLVKLWDLTAG 217

Query: 1427 LL 1428
             L
Sbjct: 218  KL 223

 Score = 35.8 bits (81), Expect = 0.12,   Method: Compositional matrix adjust.
 Identities = 24/77 (31%), Positives = 36/77 (46%)
 Frame = +2

Query: 31  GGTIVTGCHDGQICLWDVSVELEVNPRALLFGHTASITCLSKACASGDKRYTVSASANGE 90
           G    +G  D  + LWD+  +  +       GHT  + CL     S D R+  SAS +G 
Sbjct: 29  GAYTASGSMDCNVKLWDIRRKGCI---YTYKGHTGCVCCLR---FSPDGRWIASASEDGL 190

Query: 91  MCLWDVNDGRCIEFTKL 107
           + LWD+  G+ +   KL
Sbjct: 191 VKLWDLTAGKLLTDLKL 241
>17266
          Length = 480

 Score = 40.4 bits (93), Expect = 0.005,   Method: Composition-based stats.
 Identities = 19/45 (42%), Positives = 27/45 (60%), Gaps = 1/45 (2%)
 Frame = -1

Query: 1370 GARHGSVALYDIRTGKC-QTIHGHKGPITAVSFAPDGRYLATYSN 1413
            GA   S  L+D+R G C QT  GH+  I A+++ P+G   AT S+
Sbjct: 405  GACDASAKLWDVRDGMCKQTFSGHESDINAITYFPNGHAFATGSD 271

 Score = 35.4 bits (80), Expect = 0.18,   Method: Composition-based stats.
 Identities = 30/120 (25%), Positives = 47/120 (39%), Gaps = 6/120 (5%)
 Frame = -1

Query: 481 DQRYLISGGVDFSVIIWDIFSGEMKHIFCVHGGEITQLLVPPENCSARVQHCICSVASDH 540
           D R  +SG  D S  +WD+  G  K  F  H  +I  +   P        H   + + D 
Sbjct: 426 DMRTFVSGACDASAKLWDVRDGMCKQTFSGHESDINAITYFPNG------HAFATGSDDA 265

Query: 541 SVGLLSLREKKCIMLASRH--LFPIQVIKWRPSDDYLVVGCTDGSVYVW----QMDTGAL 594
           +  L  +R  + I + S    +  I  + +  S   L+ G  D +  +W    Q  TG L
Sbjct: 264 TCRLFDIRADQEIGMYSHDNIICGITSVAFSKSGRLLLGGYDDFNCNIWDVLKQERTGVL 85
>13278
          Length = 870

 Score = 40.0 bits (92), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 21/63 (33%), Positives = 37/63 (58%), Gaps = 1/63 (1%)
 Frame = +1

Query: 1367 IAVGARHGSVALYDIRTGKC-QTIHGHKGPITAVSFAPDGRYLATYSNTDSHISFWQMNT 1425
            +A  +   +V L+++  G C  T+  H+ P+ +V+F+PDG+YLA+ S  D  +  W + T
Sbjct: 121  LASASFDSTVRLWEVERGLCLHTLTKHQEPVYSVAFSPDGKYLASGS-FDKCVHIWNVQT 297

Query: 1426 SLL 1428
              L
Sbjct: 298  GSL 306

 Score = 37.7 bits (86), Expect = 0.038,   Method: Compositional matrix adjust.
 Identities = 44/147 (29%), Positives = 64/147 (43%), Gaps = 1/147 (0%)
 Frame = +1

Query: 429 SIIIVPATQTAIVQLLQGEHMLRRGWPPHRTLRGHRNKVTCLLYPHQVSARYDQRYLISG 488
           S+I+  A+  + V+L + E    RG   H TL  H+  V      + V+   D +YL SG
Sbjct: 112 SLILASASFDSTVRLWEVE----RGLCLH-TLTKHQEPV------YSVAFSPDGKYLASG 258

Query: 489 GVDFSVIIWDIFSGEMKHIFCVHGGEITQLLVPPENCSARVQHCICSVASDHSVGLLSLR 548
             D  V IW++ +G + H +   GG         E C       + + ASD SV +L LR
Sbjct: 259 SFDKCVHIWNVQTGSLVHSYKGTGGIF-------EVCWNHRGDKVGASASDGSVFVLDLR 417

Query: 549 E-KKCIMLASRHLFPIQVIKWRPSDDY 574
           +  KC       L P    K+ P   Y
Sbjct: 418 K*DKCSNSWHMLLLPPLSPKFLPCAGY 498
>27270
          Length = 1078

 Score = 38.1 bits (87), Expect = 0.026,   Method: Compositional matrix adjust.
 Identities = 22/61 (36%), Positives = 33/61 (54%), Gaps = 2/61 (3%)
 Frame = +2

Query: 1367 IAVGARHGSVALYDIRTGKCQTI--HGHKGPITAVSFAPDGRYLATYSNTDSHISFWQMN 1424
            +AVG+  GSV LY + T     +   GH   +T + +  DGR L + S+ D H+  W +N
Sbjct: 188  VAVGSADGSVGLYSVETHTYTHMLNKGHSKAVTDMCWRADGRTLYS-SSLDGHVIGWNVN 364

Query: 1425 T 1425
            T
Sbjct: 365  T 367
>12806
          Length = 961

 Score = 37.7 bits (86), Expect = 0.035,   Method: Compositional matrix adjust.
 Identities = 37/158 (23%), Positives = 70/158 (44%), Gaps = 7/158 (4%)
 Frame = +3

Query: 456 PHRTLRGHRNKVTCLLYPHQVSARYDQRYLISGGVDFSVIIWDIFSGEMKHIFCVHGGEI 515
           P +TL GH + ++ L     +SA  D R+ +S   D ++ +WDI  G     F  H  ++
Sbjct: 141 PRKTLTGHSHFISDL----ALSA--DSRFALSSSWDATLRLWDIKKGSTTSRFINHTRDV 302

Query: 516 TQLLVPPENCSARVQHCICSVASDHSVGLLSLR-EKKCIMLASRHLFPIQVIKWR--PSD 572
             +   P+N        I S   D ++ + ++  E K  + A+ H   +  +++     +
Sbjct: 303 LTVAFSPDN------RQIASGGRDKNLKIWNIMGECKYTVDANAHTDWVTCVRFHQDTKN 464

Query: 573 DYLVVGCTDGSVYVWQMDTGALDRCAMG----ITAVEI 606
             +V    D ++ VW   T  L    +G    ITA+++
Sbjct: 465 PIVVSASNDKTIKVWDNHTMTLKNTFVGHKAQITALDM 578

 Score = 30.4 bits (67), Expect = 5.9,   Method: Composition-based stats.
 Identities = 13/32 (40%), Positives = 20/32 (62%)
 Frame = +3

Query: 468 TCLLYPHQVSARYDQRYLISGGVDFSVIIWDI 499
           T + Y  QV     + +LISGG D ++I+WD+
Sbjct: 3   TTMQYGEQVVDGATKPFLISGGRDNNIIVWDL 98
>02147
          Length = 1547

 Score = 37.7 bits (86), Expect = 0.040,   Method: Compositional matrix adjust.
 Identities = 22/75 (29%), Positives = 32/75 (42%), Gaps = 1/75 (1%)
 Frame = +2

Query: 1349 FPAICRFYMVSYYERSHRIAVGARHGSVALYDIRTGK-CQTIHGHKGPITAVSFAPDGRY 1407
            F A       S ++       G     +  +D  TGK  ++  GH GP+  V F+PDG  
Sbjct: 659  FEAEAPISSASLHQSERFFVAGGEDFKMYKFDYETGKEIESFKGHFGPVHCVRFSPDGEL 838

Query: 1408 LATYSNTDSHISFWQ 1422
             A+ S  D  +  WQ
Sbjct: 839  YASGSE-DGTLRLWQ 880
>29912
          Length = 510

 Score = 37.4 bits (85), Expect = 0.051,   Method: Compositional matrix adjust.
 Identities = 24/91 (26%), Positives = 47/91 (51%), Gaps = 3/91 (3%)
 Frame = +3

Query: 1367 IAVGARHGSVALYDIRTGKCQ--TIHGHKGPITAVSFAPDGRYLATYSNTDSHISFWQMN 1424
            ++ G+R G++  +D+R       T+ GH   +  + ++PDG+YLA+ +N D+ +  W   
Sbjct: 174  VSSGSRSGNIHHHDVRVADHHVGTLSGHSQEVCGLRWSPDGKYLASGAN-DNLLCVWPAQ 350

Query: 1425 TSLLGSIGMLNSAPQLR-CIKTYQVPPVQPA 1454
             +   S   L++  Q +  +K     P QP+
Sbjct: 351  VTGGNSTQPLHTFSQHQAAVKALAWCPWQPS 443

 Score = 32.7 bits (73), Expect = 1.0,   Method: Compositional matrix adjust.
 Identities = 31/121 (25%), Positives = 43/121 (35%), Gaps = 5/121 (4%)
 Frame = +3

Query: 472 YPHQVSARYDQRYLISGGVDFSVIIWDIFSGEMKHIFCVHGGEITQL-----LVPPENCS 526
           Y   VS   +  YL  G     V +WD+   +       H   +  L     +V   + S
Sbjct: 15  YIGAVSWIKEGNYLALGTSTGEVQVWDVTQQKKLRTMAGHAARVGSLSWNSFIVSSGSRS 194

Query: 527 ARVQHCICSVASDHSVGLLSLREKKCIMLASRHLFPIQVIKWRPSDDYLVVGCTDGSVYV 586
             + H    VA DH VG LS   ++   L           +W P   YL  G  D  + V
Sbjct: 195 GNIHHHDVRVA-DHHVGTLSGHSQEVCGL-----------RWSPDGKYLASGANDNLLCV 338

Query: 587 W 587
           W
Sbjct: 339 W 341
>27806
          Length = 419

 Score = 35.0 bits (79), Expect = 0.20,   Method: Compositional matrix adjust.
 Identities = 15/63 (23%), Positives = 30/63 (47%), Gaps = 1/63 (1%)
 Frame = -1

Query: 527 ARVQHCICSVAS-DHSVGLLSLREKKCIMLASRHLFPIQVIKWRPSDDYLVVGCTDGSVY 585
           +R  H I   AS DH+  + S+    C++    H   +  +++ P  D ++    D + +
Sbjct: 401 SRPGHPIIGTASADHTARIYSIETGACVLTYGGHQGSVNAVRFHPGQDLVLTASGDHTAH 222

Query: 586 VWQ 588
           VW+
Sbjct: 221 VWR 213
>01327
          Length = 2215

 Score = 34.3 bits (77), Expect = 0.38,   Method: Compositional matrix adjust.
 Identities = 26/111 (23%), Positives = 48/111 (43%)
 Frame = +3

Query: 486 ISGGVDFSVIIWDIFSGEMKHIFCVHGGEITQLLVPPENCSARVQHCICSVASDHSVGLL 545
           +SG  D SV+++D  +G ++  +  H  EIT++      C     + + S + D ++ + 
Sbjct: 87  LSGSKDKSVVLYDYQNGRLEDRWTGHDREITKV------CYGASCNGMFSASRDKTIKMW 248

Query: 546 SLREKKCIMLASRHLFPIQVIKWRPSDDYLVVGCTDGSVYVWQMDTGALDR 596
                  I     H   +  I     +  L  G  D +V +W ++TGA  R
Sbjct: 249 QRGNSHSIRDFIGHDMVVTAIHLNTDNTLLCSGSRDNTVRIWDVETGACLR 401
>34005
          Length = 456

 Score = 33.9 bits (76), Expect = 0.45,   Method: Compositional matrix adjust.
 Identities = 24/74 (32%), Positives = 36/74 (48%), Gaps = 6/74 (8%)
 Frame = +1

Query: 1358 VSYYERSHRIAVGARHGSVALYDIRTG----KCQTIHGHKGPITAVSFAP-DGRYLATYS 1412
            +S+   +  +A G+   SV ++D   G       T+  H+  + AV++ P   R LAT  
Sbjct: 130  LSWSPDATFLASGSNDNSVNIWDSTLGMDVPPLHTLTSHQAAVKAVAWCPWQTRMLATGG 309

Query: 1413 NT-DSHISFWQMNT 1425
             T D HI FW  NT
Sbjct: 310  GTNDRHIRFWNTNT 351
>19863
          Length = 502

 Score = 33.5 bits (75), Expect = 0.68,   Method: Composition-based stats.
 Identities = 19/79 (24%), Positives = 37/79 (46%)
 Frame = +1

Query: 481 DQRYLISGGVDFSVIIWDIFSGEMKHIFCVHGGEITQLLVPPENCSARVQHCICSVASDH 540
           D   L+SG  D S+++WD+ +G  K     H G +  +    + C       + S ++D+
Sbjct: 4   DGLQLVSGSSDMSIVVWDVENGVQKLRLQGHAGWVNDVHFSQDQC------WLLSCSNDN 165

Query: 541 SVGLLSLREKKCIMLASRH 559
           +V + ++ E   I +   H
Sbjct: 166 TVRIWNIEESDQIPIVMEH 222
>03387
          Length = 1891

 Score = 33.5 bits (75), Expect = 0.71,   Method: Compositional matrix adjust.
 Identities = 17/59 (28%), Positives = 29/59 (49%), Gaps = 2/59 (3%)
 Frame = +1

Query: 1367 IAVGARHGSVALYDIRTGKCQ--TIHGHKGPITAVSFAPDGRYLATYSNTDSHISFWQM 1423
            +A G+   +VAL+D+R  K +  +   HK  I  V ++P    +   S TD  +  W +
Sbjct: 697  LATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLHVWDL 873

 Score = 30.4 bits (67), Expect = 5.0,   Method: Compositional matrix adjust.
 Identities = 16/59 (27%), Positives = 28/59 (47%)
 Frame = +1

Query: 40  DGQICLWDVSVELEVNPRALLFGHTASITCLSKACASGDKRYTVSASANGEMCLWDVND 98
           D ++ +WD        P  ++  HTA + CLS    S  +    + SA+  + LWD+ +
Sbjct: 577 DQKLMIWDTRSNTTSKPSHVVDAHTAEVNCLSFNPYS--EFILATGSADKTVALWDLRN 747
>15780
          Length = 735

 Score = 33.1 bits (74), Expect = 0.77,   Method: Compositional matrix adjust.
 Identities = 20/65 (30%), Positives = 29/65 (44%)
 Frame = -1

Query: 483 RYLISGGVDFSVIIWDIFSGEMKHIFCVHGGEITQLLVPPENCSARVQHCICSVASDHSV 542
           +YL + G D +VI+WDI SG        H   +  L      C +R    + S   D+S+
Sbjct: 735 KYLSTAGADHTVIVWDIASGTAVAHLTAHTDTVYAL------CFSRDGTVLASGGMDNSI 574

Query: 543 GLLSL 547
            L  L
Sbjct: 573 RLWDL 559
>27465
          Length = 658

 Score = 33.1 bits (74), Expect = 0.78,   Method: Compositional matrix adjust.
 Identities = 19/80 (23%), Positives = 37/80 (46%)
 Frame = -1

Query: 22  ISSILLTDDGGTIVTGCHDGQICLWDVSVELEVNPRALLFGHTASITCLSKACASGDKRY 81
           ++++     G + +TG +D    +WD +   E++    L GH   +  ++     GDK  
Sbjct: 352 LTNVAFNKSGSSFITGSYDRTCKIWDTASAEELHT---LEGHRNVVYAIAFNNPFGDK-- 188

Query: 82  TVSASANGEMCLWDVNDGRC 101
            ++ S +    LW   DG+C
Sbjct: 187 VITGSFDKTCKLWSTADGKC 128

 Score = 31.6 bits (70), Expect = 2.9,   Method: Compositional matrix adjust.
 Identities = 18/59 (30%), Positives = 27/59 (45%), Gaps = 1/59 (1%)
 Frame = -1

Query: 1366 RIAVGARHGSVALYDIRTGKC-QTIHGHKGPITAVSFAPDGRYLATYSNTDSHISFWQM 1423
            ++  G+   +  L+    GKC  T+ GH   I  VSF P    +AT S  D+    W +
Sbjct: 190  KVITGSFDKTCKLWSTADGKCYHTLRGHTAEIVCVSFNPSSTLIATGS-MDTTCRLWDV 17
>03395
          Length = 2795

 Score = 32.7 bits (73), Expect = 1.00,   Method: Composition-based stats.
 Identities = 20/80 (25%), Positives = 39/80 (48%), Gaps = 5/80 (6%)
 Frame = +2

Query: 22 ISSILLTDDGGTIVTGCHDGQICLWDVSVELEVNPR-----ALLFGHTASITCLSKACAS 76
          +++I +T  G  +V+G  +GQ+ +WD+  ++          A +  H   +T +      
Sbjct: 5  VTAIAVTSCGTKLVSGGGEGQVRVWDIVKDMLTGKTRGDLVANMKEHKGKVTAIQ---IH 175

Query: 77 GDKRYTVSASANGEMCLWDV 96
           + R  VSAS +G   +WD+
Sbjct: 176TNDRCCVSASTDGSTIIWDL 235
>15118
          Length = 1074

 Score = 32.7 bits (73), Expect = 1.1,   Method: Composition-based stats.
 Identities = 20/61 (32%), Positives = 33/61 (54%), Gaps = 1/61 (1%)
 Frame = +3

Query: 1364 SHRIAVGARHGSVALYDIRTGKC-QTIHGHKGPITAVSFAPDGRYLATYSNTDSHISFWQ 1422
            S+ +AV     +V++ D+ T +  +   GH   IT +SF+ DGR+L T S  D  +  W 
Sbjct: 363  SNMLAVVLEDFTVSVIDVDTLRVVRVFSGHSNSITDLSFSGDGRWLITAS-MDCTVRTWS 539

Query: 1423 M 1423
            +
Sbjct: 540  L 542
>12960
          Length = 550

 Score = 32.3 bits (72), Expect = 1.4,   Method: Compositional matrix adjust.
 Identities = 31/116 (26%), Positives = 50/116 (43%), Gaps = 3/116 (2%)
 Frame = +2

Query: 454 WPPHRTLRGHRNKVTCLLYPHQV---SARYDQRYLISGGVDFSVIIWDIFSGEMKHIFCV 510
           W PHR L       T + + H+V       D   + SGG+D +V+++D+ SG+    +  
Sbjct: 254 WNPHRELFLK----TYIGHGHEVLDAQGSGDNSQICSGGIDKTVVLFDVASGQALRKYRD 421

Query: 511 HGGEITQLLVPPENCSARVQHCICSVASDHSVGLLSLREKKCIMLASRHLFPIQVI 566
           H G +  +    E+        I S + D++V     R        SR   PIQV+
Sbjct: 422 HAGTVNCVKFNEEST------VILSGSLDNTVRAWDTR--------SRSHTPIQVL 547
>28151
          Length = 1429

 Score = 32.0 bits (71), Expect = 1.9,   Method: Compositional matrix adjust.
 Identities = 17/50 (34%), Positives = 24/50 (48%), Gaps = 9/50 (18%)
 Frame = +3

Query: 570 PSDDYLVVGCTDGSVYV---------WQMDTGALDRCAMGITAVEILNAC 610
           P   Y++VGC D  +YV         WQ+ TG + +C+    AV  L  C
Sbjct: 168 PCGQYVIVGCYDNKIYVLKASTGEVEWQVRTGEMVKCSPVSHAVSRLVFC 317
>21921
          Length = 1341

 Score = 31.6 bits (70), Expect = 2.2,   Method: Compositional matrix adjust.
 Identities = 16/61 (26%), Positives = 33/61 (54%), Gaps = 1/61 (1%)
 Frame = -1

Query: 57  RALLF-GHTASITCLSKACASGDKRYTVSASANGEMCLWDVNDGRCIEFTKLACTHTGIQ 115
           +AL++ GHT  +  +   C     ++ VS S +G +  W+V+ GRC++  ++    T + 
Sbjct: 507 QALVYKGHTGIVRSI---CPDPTGQWLVSGSDDGTIRFWEVSSGRCMKTLQVGGCVTSVA 337

Query: 116 F 116
           +
Sbjct: 336 W 334
>12574
          Length = 521

 Score = 31.6 bits (70), Expect = 2.3,   Method: Composition-based stats.
 Identities = 14/34 (41%), Positives = 22/34 (64%)
 Frame = +3

Query: 1388 TIHGHKGPITAVSFAPDGRYLATYSNTDSHISFW 1421
            T+ GH   ++AV F+P+G +LA+ S+ D  I  W
Sbjct: 171  TLAGHTKALSAVKFSPNGDWLAS-SSADKLIKIW 269
>14124
          Length = 750

 Score = 31.6 bits (70), Expect = 2.4,   Method: Compositional matrix adjust.
 Identities = 19/51 (37%), Positives = 24/51 (47%)
 Frame = +3

Query: 1387 QTIHGHKGPITAVSFAPDGRYLATYSNTDSHISFWQMNTSLLGSIGMLNSA 1437
            QTI      I  V F P G YL     +D   +FW +    +GS+G  NSA
Sbjct: 258  QTITTFLQNIMEVGFPP-GSYLVDEDISDMSXNFWYLLQDAMGSLGERNSA 407
>19498
          Length = 903

 Score = 31.6 bits (70), Expect = 2.5,   Method: Compositional matrix adjust.
 Identities = 14/34 (41%), Positives = 21/34 (61%)
 Frame = -1

Query: 1389 IHGHKGPITAVSFAPDGRYLATYSNTDSHISFWQ 1422
            I GH G +  V++ P GRYLA+ S+ D  +  W+
Sbjct: 492  IRGHAGMVKGVTWDPVGRYLASQSD-DKTLRVWR 394
>18981
          Length = 407

 Score = 31.6 bits (70), Expect = 2.6,   Method: Composition-based stats.
 Identities = 19/58 (32%), Positives = 30/58 (51%)
 Frame = -2

Query: 459 TLRGHRNKVTCLLYPHQVSARYDQRYLISGGVDFSVIIWDIFSGEMKHIFCVHGGEIT 516
           TLRGH + V C+         Y +R ++SG  D ++I+W++ +G   H    H   IT
Sbjct: 313 TLRGHNDDVECVCI-------YGRR-VVSGSWDKTLIVWEVDTGRPVHQLHGHTEAIT 164

 Score = 30.4 bits (67), Expect = 5.0,   Method: Composition-based stats.
 Identities = 17/61 (27%), Positives = 33/61 (54%), Gaps = 1/61 (1%)
 Frame = -2

Query: 1366 RIAVGARHGSVALYDIRTGK-CQTIHGHKGPITAVSFAPDGRYLATYSNTDSHISFWQMN 1424
            R+  G+   ++ ++++ TG+    +HGH   ITAV F  +G+  A   + D  +  W ++
Sbjct: 262  RVVSGSWDKTLIVWEVDTGRPVHQLHGHTEAITAVQF-DEGK--AVSGSADGDVRTWALD 92

Query: 1425 T 1425
            T
Sbjct: 91   T 89
>26939
          Length = 388

 Score = 31.2 bits (69), Expect = 3.2,   Method: Composition-based stats.
 Identities = 14/56 (25%), Positives = 27/56 (48%)
 Frame = +2

Query: 533 ICSVASDHSVGLLSLREKKCIMLASRHLFPIQVIKWRPSDDYLVVGCTDGSVYVWQ 588
           + S + D ++ +  LR K+C+     H      I +  +  Y++ G  D +V VW+
Sbjct: 11  LVSASDDKTIRVWDLRNKRCMKTLYAHQHFCTSIDFHKAHPYVISGSVDQTVKVWE 178
>00561
          Length = 1003

 Score = 31.2 bits (69), Expect = 3.6,   Method: Compositional matrix adjust.
 Identities = 15/62 (24%), Positives = 33/62 (53%)
 Frame = -3

Query: 462 GHRNKVTCLLYPHQVSARYDQRYLISGGVDFSVIIWDIFSGEMKHIFCVHGGEITQLLVP 521
           GH + V+C+ +    S  +    ++S G D +V +W++ + ++K+    H G +  + V 
Sbjct: 617 GHTDWVSCVRF----SPNHSNPIIVSCGWDRTVKVWNLANCKLKNNHHGHNGYLNTVTVS 450

Query: 522 PE 523
           P+
Sbjct: 449 PD 444

 Score = 29.6 bits (65), Expect = 9.1,   Method: Compositional matrix adjust.
 Identities = 14/35 (40%), Positives = 18/35 (51%)
 Frame = -3

Query: 1390 HGHKGPITAVSFAPDGRYLATYSNTDSHISFWQMN 1424
            HGH G +  V+ +PDG  L T    DS    W +N
Sbjct: 488  HGHNGYLNTVTVSPDGS-LCTSGGKDSKALLWDLN 387
>01462
          Length = 995

 Score = 30.8 bits (68), Expect = 3.9,   Method: Compositional matrix adjust.
 Identities = 31/120 (25%), Positives = 56/120 (46%), Gaps = 8/120 (6%)
 Frame = +2

Query: 22  ISSILLTDDGGT--IVTGCHDGQICLWDVSVELEVNPRALLFGHTASITCLSKACASGDK 79
           ++SI + +  GT  +  G  D +I +WD+     +N    + GH   I    K     D 
Sbjct: 200 VNSIAVDEKMGTRRLYAGAGDRKIHVWDIEAGQYLNA---MEGHKDYI---HKVVMKNDA 361

Query: 80  RYTVSASANGEMCLWDVNDG----RCIEFTKLA-CTHTGI-QFYQFSVGNQQEGRLLCHG 133
           +  VSAS +G + +WD+        C+E +K   C+   + ++ +    + +EG L+C G
Sbjct: 362 QECVSASEDGTVRMWDIRSSTETVHCLEPSKNELCSRPLLGKWLRCLALDPEEGWLVCGG 541
>34541
          Length = 491

 Score = 30.8 bits (68), Expect = 4.0,   Method: Compositional matrix adjust.
 Identities = 15/33 (45%), Positives = 19/33 (57%)
 Frame = +2

Query: 1211 WEPYMDVSAVLMGLLELCADAEKQLANITMGLP 1243
            W P  DVSA+L   ++LC     Q+A  TM LP
Sbjct: 92   WSPTYDVSAILTS-IQLCFTTPTQIAQPTMKLP 187
>21513
          Length = 1226

 Score = 30.8 bits (68), Expect = 4.1,   Method: Composition-based stats.
 Identities = 18/47 (38%), Positives = 28/47 (59%)
 Frame = -3

Query: 414 YIPAHGRLVCGREDGSIIIVPATQTAIVQLLQGEHMLRRGWPPHRTL 460
           ++P +GRL+ GR+ G  +IV +TQ  +VQL     +LR G    R +
Sbjct: 840 HLPLNGRLLFGRDSGFGLIVYSTQ-PVVQLASHRLVLRTGLEVDRVI 703
>13412
          Length = 797

 Score = 30.4 bits (67), Expect = 5.1,   Method: Composition-based stats.
 Identities = 26/96 (27%), Positives = 48/96 (50%), Gaps = 7/96 (7%)
 Frame = +2

Query: 1268 AFITTIAKEVHRHTALAA--NTQSQQSIHTTTL-----ARAKGEILRVIEILIEKMPTDV 1320
            A I T++  V  + A  A  N  S+  I+  T+      +   EI++VI+  IEK+PT+ 
Sbjct: 107  ALIDTMSDAVESYRAALADLNFNSKPLINMLTMLAEESEQMASEIVQVIDDQIEKVPTNQ 286

Query: 1321 VDLLVEVMDIIMYCLEGSLVKKKGLQECFPAICRFY 1356
               L+ ++D ++  L  +L  +  +Q+     CR +
Sbjct: 287  KLPLLYLIDSMIKNLTSTLYPQLFIQKIVALFCRVF 394
>10162
          Length = 1629

 Score = 30.4 bits (67), Expect = 6.3,   Method: Compositional matrix adjust.
 Identities = 30/122 (24%), Positives = 49/122 (40%), Gaps = 4/122 (3%)
 Frame = +3

Query: 476 VSARYDQRYLISGGVDFSVIIWDIFSGEMKHIFCVHGGEITQLLVPPENCSARVQHCICS 535
           V    D   ++SG  D +  ++++ SG++   F     + +Q     +N    V  C  S
Sbjct: 387 VDCSADNALIMSGCADATAKVFNVSSGKLXSAFNCAASQDSQ---DKDNSVESVAFCPVS 557

Query: 536 VASDHSVGLLSLREKKCIMLASRHLF--PIQVIK--WRPSDDYLVVGCTDGSVYVWQMDT 591
             +  +    S++        +RH F  P  V K  W  S   L   C DG + VW   +
Sbjct: 558 PYAATATNSGSVQVWDLPTSVARHSFQHPEGVCKLQWSSSTALLYTACLDGVMRVWDARS 737

Query: 592 GA 593
           GA
Sbjct: 738 GA 743
>17602
          Length = 481

 Score = 30.0 bits (66), Expect = 6.5,   Method: Compositional matrix adjust.
 Identities = 22/92 (23%), Positives = 41/92 (44%), Gaps = 5/92 (5%)
 Frame = +3

Query: 1360 YYERSHRIAVGARH-GSVALYDIRTGKC--QTIHGHKGPITAVSFAPDGRYL--ATYSNT 1414
            ++ R   + V + + G   ++D  +G+C    I     P++ V F+P+G+Y+  AT  NT
Sbjct: 75   HFNRDGSLIVSSSYDGLCRIWDTASGQCLXTLIDDDNPPVSFVKFSPNGKYILAATLDNT 254

Query: 1415 DSHISFWQMNTSLLGSIGMLNSAPQLRCIKTY 1446
               +  W  +                +C+KTY
Sbjct: 255  ---LKLWDYSKG--------------KCLKTY 299
>14500
          Length = 1238

 Score = 30.0 bits (66), Expect = 7.7,   Method: Composition-based stats.
 Identities = 12/34 (35%), Positives = 22/34 (64%)
 Frame = +2

Query: 1388 TIHGHKGPITAVSFAPDGRYLATYSNTDSHISFW 1421
            T+ GH   +  + ++PDG+YLA+ +N D+ +  W
Sbjct: 44   TLSGHSQEVCGLRWSPDGKYLASGAN-DNLLCVW 142
>02090
          Length = 1841

 Score = 29.6 bits (65), Expect = 8.7,   Method: Compositional matrix adjust.
 Identities = 20/77 (25%), Positives = 36/77 (46%)
 Frame = -3

Query: 24   SILLTDDGGTIVTGCHDGQICLWDVSVELEVNPRALLFGHTASITCLSKACASGDKRYTV 83
            ++ ++ DG    + C DG I +WD+  +  V       GHT   +C+  +   G K +T 
Sbjct: 1611 ALAISPDGKVCFSCCSDGNIAVWDLHNQTLVRQ---FQGHTDGASCIDIS-PDGTKLWT- 1447

Query: 84   SASANGEMCLWDVNDGR 100
                +  +  WD+ +GR
Sbjct: 1446 -GGLDNTVRSWDLREGR 1399
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|46195711|ref|NP_034277.1| epsin 1 [Mus musculus]
         (575 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

20172                                                                  48   1e-05
29029                                                                  40   0.002
>20172
          Length = 479

 Score = 47.8 bits (112), Expect = 1e-05,   Method: Composition-based stats.
 Identities = 20/44 (45%), Positives = 32/44 (72%)
 Frame = +2

Query: 88  GSERVSQQCKENMYAVQTLKDFQYVDRDGKDQGVNVREKAKQLV 131
           GSERV    +E++Y ++ L+ + + D +GKDQG+NVR K K+L+
Sbjct: 2   GSERVVTSSREHLYDLRGLESYSFTDENGKDQGLNVRHKVKELI 133
>29029
          Length = 467

 Score = 40.4 bits (93), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 33/77 (42%), Positives = 57/77 (74%), Gaps = 2/77 (2%)
 Frame = -3

Query: 203 PSCGPEDDVQLQLALSLSREEHDKEERIRRGDDLRLQMAIEESKRETGGKEES-SLMDLA 261
           PS   E+++QLQ+AL+LS+EEH++E +  + D+++LQMA+E+SK+ T  ++ + SL+D++
Sbjct: 297 PSSPGEEELQLQIALALSKEEHEEEVKKYQSDEVKLQMALEQSKQTTTTQQTTESLLDMS 118

Query: 262 DVFTTPAPPQA-SDPWG 277
           +    PA   A +DPWG
Sbjct: 117 NSLQAPAAAAANTDPWG 67
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6754690|ref|NP_035974.1| monoglyceride lipase [Mus
musculus]
         (303 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

05344                                                                  47   1e-05
03845                                                                  39   0.003
08863                                                                  35   0.049
35873                                                                  32   0.42 
27390                                                                  28   3.1  
19083                                                                  28   5.7  
>05344
          Length = 1178

 Score = 46.6 bits (109), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 32/102 (31%), Positives = 49/102 (48%), Gaps = 1/102 (0%)
 Frame = -2

Query: 45  IFVSHGAGEHCGRYDELAHMLKGLDMLVFAHDHVGHGQSEGERMVVSDFQVFV-RDVLQH 103
           I   HG  ++CG +D L  +L   D  V A D  GHG S          Q F+  D +  
Sbjct: 961 ILALHGWQDNCGSFDRLCPLLPA-DCSVLAIDLPGHGNSS---HYPKGMQYFIFWDGISL 794

Query: 104 VDTIQKDYPDVPIFLLGHSMGGAISILVAAERPTYFSGMVLI 145
           +  I + +    + L+GHS+GGA++ + AA  P   S ++ I
Sbjct: 793 IRRIVRKFNWKNVVLMGHSLGGALTFMYAASFPNEVSKLINI 668
>03845
          Length = 1326

 Score = 38.5 bits (88), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 27/92 (29%), Positives = 43/92 (46%), Gaps = 2/92 (2%)
 Frame = +2

Query: 38  SGTPKALIFVSHGAGEHCGRYDELAHM--LKGLDMLVFAHDHVGHGQSEGERMVVSDFQV 95
           SGTP  +   +HG+G    ++  +     L+G +  V   D+ G G S GE         
Sbjct: 248 SGTP--IFIYAHGSGGSRSQFTRVYTYTALRGQEFHVVTFDYRGFGDSTGEATESH---- 409

Query: 96  FVRDVLQHVDTIQKDYPDVPIFLLGHSMGGAI 127
            V D++     ++K     P+FL GHS+GG +
Sbjct: 410 MVEDLVTVFRWVKKRAWKSPVFLWGHSLGGGV 505
>08863
          Length = 458

 Score = 34.7 bits (78), Expect = 0.049,   Method: Compositional matrix adjust.
 Identities = 12/31 (38%), Positives = 20/31 (64%)
 Frame = +1

Query: 5  SSPRRTPQNVPYQDLPHLVNADGQYLFCRYW 35
           + +++PQ+VPY DL H +N   + LF + W
Sbjct: 64 KTAKKSPQSVPYTDLKHKINTYAKDLFQKEW 156
>35873
          Length = 435

 Score = 31.6 bits (70), Expect = 0.42,   Method: Compositional matrix adjust.
 Identities = 20/68 (29%), Positives = 29/68 (42%)
 Frame = +2

Query: 80  HGQSEGERMVVSDFQVFVRDVLQHVDTIQKDYPDVPIFLLGHSMGGAISILVAAERPTYF 139
           H  SE E M V           Q ++  +K        LLGHS+GG +S   A   P + 
Sbjct: 203 HNPSEAEDMFV-----------QSIENYRKAMGLEKFILLGHSLGGFLSASYALRHPQHI 349

Query: 140 SGMVLISP 147
             ++L+ P
Sbjct: 350 KHLILVDP 373
>27390
          Length = 703

 Score = 28.5 bits (62), Expect = 3.1,   Method: Compositional matrix adjust.
 Identities = 12/45 (26%), Positives = 24/45 (53%), Gaps = 2/45 (4%)
 Frame = +1

Query: 107 IQKDYPDVP--IFLLGHSMGGAISILVAAERPTYFSGMVLISPLV 149
           +  ++P +P    + GHSMGG  +++ A + P  F  +   +P+ 
Sbjct: 82  VNSNFPTLPGKQSIFGHSMGGHGALICAMKNPGMFCSVSAFAPIC 216
>19083
          Length = 459

 Score = 27.7 bits (60), Expect = 5.7,   Method: Compositional matrix adjust.
 Identities = 18/59 (30%), Positives = 28/59 (47%)
 Frame = -2

Query: 30  LFCRYWKPSGTPKALIFVSHGAGEHCGRYDELAHMLKGLDMLVFAHDHVGHGQSEGERM 88
           L+CR W+     +A  + S G    CG +D  +H      M + A    GHG++ G R+
Sbjct: 236 LYCRRWRK----EASSYHSSGHPWVCGAHDCHSHRKLCRQMAILAITAPGHGRTGGPRL 72
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|82950147|ref|XP_621314.2| PREDICTED: desmoplakin
isoform 1 [Mus musculus]
         (2883 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

23752                                                                  50   1e-05
26710                                                                  33   1.7  
04671                                                                  33   2.2  
>23752
          Length = 853

 Score = 50.1 bits (118), Expect = 1e-05,   Method: Composition-based stats.
 Identities = 29/127 (22%), Positives = 58/127 (45%), Gaps = 4/127 (3%)
 Frame = -2

Query: 363 MDTLQTQWSWILQITKCIDVHLKENAAYFQFFEEAQSTEAYLKGLQDSIRKKYPCDKNMP 422
           +  +++ W W+ Q+ +C +VHL+  AAY +FF E +  E +++     I   +  D+N  
Sbjct: 372 VQAVRSNWQWMSQVMQCAEVHLRNAAAYHEFFHEVEEAEYWMENTLSRIHMSF--DRN-K 202

Query: 423 LQHXXXXXXXXXXXXXXX----XXYKRQVQNLVNKSKKIVQLKPRNPDYRSNKPIILRAL 478
           LQ                      ++ ++  L +++K +V +  R    +  +P+I  AL
Sbjct: 201 LQGNRTDVVAIQDEIKEVLAGFLQWQTKIDYLFDRAKTVVPVPQRTTALKEERPVI--AL 28

Query: 479 CDYKQDQ 485
            D+   Q
Sbjct: 27  TDFSNSQ 7
>26710
          Length = 407

 Score = 33.1 bits (74), Expect = 1.7,   Method: Composition-based stats.
 Identities = 27/98 (27%), Positives = 45/98 (45%), Gaps = 26/98 (26%)
 Frame = +3

Query: 2632 AAIFDTENLEKISIAEGIERGIVDSITGQ--------RLLEAQACTGGIIHPTTGQK--- 2680
            ++I D +  +KI++ + I++ I D   GQ        R+   +AC  G+I  TT      
Sbjct: 33   SSIVDPKTGQKITLQQAIDQRIFDPHAGQLVHSDSMERITLQEACLEGLIPGTTDSDIQP 212

Query: 2681 ---------------LSLQDAVNQGLIDQDMATRLKPA 2703
                           L+ ++AV++GLID+D  T   PA
Sbjct: 213  RSPVRQQLVKVSVSGLTWEEAVSRGLIDEDNXTFCDPA 326

 Score = 30.4 bits (67), Expect = 9.5,   Method: Composition-based stats.
 Identities = 20/66 (30%), Positives = 33/66 (50%), Gaps = 8/66 (12%)
 Frame = +3

Query: 2645 IAEGIERGIVDSITGQRLLEAQACTGGIIHPTTGQ--------KLSLQDAVNQGLIDQDM 2696
            + +G +  IVD  TGQ++   QA    I  P  GQ        +++LQ+A  +GLI    
Sbjct: 15   VIDGHKSSIVDPKTGQKITLQQAIDQRIFDPHAGQLVHSDSMERITLQEACLEGLIPGTT 194

Query: 2697 ATRLKP 2702
             + ++P
Sbjct: 195  DSDIQP 212
>04671
          Length = 2480

 Score = 32.7 bits (73), Expect = 2.2,   Method: Composition-based stats.
 Identities = 14/31 (45%), Positives = 20/31 (64%)
 Frame = -2

Query: 891  WDLEKQIKQLRNYRDNYQSFCKWLYDAKRRQ 921
            WDL   + + R+     QSFC+WL+DA +RQ
Sbjct: 2389 WDLSGAVVESRSA----QSFCRWLHDALKRQ 2309
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|109948290|ref|NP_001035964.1| RAB, member of RAS
oncogene family-like 3 [Mus musculus]
         (236 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

17511                                                                  45   2e-05
34468                                                                  44   6e-05
13901                                                                  42   2e-04
08428                                                                  40   7e-04
30760                                                                  39   0.001
14456                                                                  39   0.002
12339                                                                  35   0.023
01398                                                                  35   0.038
35581                                                                  32   0.16 
00552                                                                  31   0.35 
26083                                                                  30   0.60 
33794                                                                  30   0.98 
09204                                                                  29   1.5  
28329                                                                  29   2.1  
33374                                                                  27   6.1  
05794                                                                  27   6.5  
>17511
          Length = 483

 Score = 45.4 bits (106), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 42/154 (27%), Positives = 67/154 (43%), Gaps = 4/154 (2%)
 Frame = -3

Query: 1   MASLDRV--KVLVLGDSGVGKSSLVHLLCHNQVLGNPSWTVGCSVDIRVHDY--KEGTPE 56
           MAS  +V  KV++LGDSGVGK+SL++   + +       T+G        D+  KE   +
Sbjct: 388 MASRKKVLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGA-------DFLTKEVMVD 230

Query: 57  EKTYYIELWDXXXXXXXXXXXXXTRAVFYNSVNGIILVHDLTNKKSSQNLYRWSLEVLNR 116
           ++   +++WD                 FY   +  +LV D+T   + ++L  W  E    
Sbjct: 229 DRLVTMQIWDTAGQERFQSLG----VAFYRGADCCVLVFDVTMPNTFRSLDSWRDE---- 74

Query: 117 DAVPTGVLVTNGDYDREQFADNQIPLLVIGTKLD 150
                  L+     D E F     P +VIG K+D
Sbjct: 73  ------FLIQASPRDPENF-----PFVVIGNKID 5
>34468
          Length = 1502

 Score = 43.9 bits (102), Expect = 6e-05,   Method: Compositional matrix adjust.
 Identities = 25/104 (24%), Positives = 49/104 (47%), Gaps = 2/104 (1%)
 Frame = +1

Query: 8   KVLVLGDSGVGKSSLVHLLCHNQVLGNPSWTVGCSVDIRVHDYKEGTPEEKTYY--IELW 65
           K++V+GDS VGK+ L +  C  +       T+G        D++E + +  + +  ++LW
Sbjct: 499 KIIVIGDSNVGKTCLTYRFCLGKFPDKTEATIGV-------DFREKSIQVDSEHLKLQLW 657

Query: 66  DXXXXXXXXXXXXXTRAVFYNSVNGIILVHDLTNKKSSQNLYRW 109
           D                 +Y +V+ ++ V+D+T   S +N+  W
Sbjct: 658 DTAGQERFRKSMVQH---YYRNVHAVVFVYDMTKMSSFENMPAW 780
>13901
          Length = 962

 Score = 42.0 bits (97), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 28/102 (27%), Positives = 48/102 (47%)
 Frame = -3

Query: 8   KVLVLGDSGVGKSSLVHLLCHNQVLGNPSWTVGCSVDIRVHDYKEGTPEEKTYYIELWDX 67
           KV+++GD  VGK+S V    ++    +   T+G    ++V  + +    +    ++LWD 
Sbjct: 282 KVIIIGDPTVGKTSFVQRYVNDSFRRDYKMTIGVDFALKVIRWSDKCNIK----LQLWDI 115

Query: 68  XXXXXXXXXXXXTRAVFYNSVNGIILVHDLTNKKSSQNLYRW 109
                       TR V+Y   +  I++ DLT K + QN  RW
Sbjct: 114 AGQERFTSM---TR-VYYKDAHACIVMFDLTQKNTYQNAIRW 1
>08428
          Length = 1109

 Score = 40.4 bits (93), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 31/123 (25%), Positives = 52/123 (42%)
 Frame = -3

Query: 7    VKVLVLGDSGVGKSSLVHLLCHNQVLGNPSWTVGCSVDIRVHDYKEGTPEEKTYYIELWD 66
            VKV +LGDSGVGKSS+V          +   T+G S        K    +   Y  ++WD
Sbjct: 1068 VKVCLLGDSGVGKSSIVLRFVTGSYRPSQESTIGAS-----FMSKSLVVDGAGYRFQIWD 904

Query: 67   XXXXXXXXXXXXXTRAVFYNSVNGIILVHDLTNKKSSQNLYRWSLEVLNRDAVPTGVLVT 126
                            ++Y      ++V+D+T  ++ +++  W ++ L     P  VL  
Sbjct: 903  TAGQEKFRALA----PMYYRGAAAAVIVYDVTRPRTFKSVKSW-IQELRSFGPPNIVLAI 739

Query: 127  NGD 129
             G+
Sbjct: 738  AGN 730
>30760
          Length = 596

 Score = 39.3 bits (90), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 34/127 (26%), Positives = 59/127 (46%), Gaps = 5/127 (3%)
 Frame = -1

Query: 6   RVKVLVLGDSGVGKSSLVHLLCHNQVLGNP---SWTVGCSVDIRVHDYKEGTPEEKTYYI 62
           R K +V GDSGVGKSS+  +  H+     P   S T G  V +++ +  +   +     +
Sbjct: 530 RAKCIVTGDSGVGKSSICQVF-HSDSAHFPKNYSMTTGVEVLVKLVNIPDSRDQ-----V 369

Query: 63  ELWDXXXXXXXXXXXXXTRAVFYNSVNGIILVHDLTNKKSSQNLYRW--SLEVLNRDAVP 120
           EL+              T+  F++  + +++V+D+T++ S     RW   +     + V 
Sbjct: 368 ELYLFDSAGKEIFSENVTK--FWDQPSVVMVVYDVTDETSFSGCVRWLERVRAAKPNTVI 195

Query: 121 TGVLVTN 127
            GVLV N
Sbjct: 194 PGVLVAN 174
>14456
          Length = 1867

 Score = 39.3 bits (90), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 35/142 (24%), Positives = 54/142 (38%), Gaps = 3/142 (2%)
 Frame = -1

Query: 12   LGDSGVGKSSLVHLLCHNQVLGNPSWTVGCSV---DIRVHDYKEGTPEEKTYYIELWDXX 68
            L   GVGKSSL++    N+       T+G      D+ V D        +TY +++WD  
Sbjct: 1123 LKQGGVGKSSLMNRFVSNKFDAQSFHTIGVEFLNKDVVVDD--------ETYTMQIWDTA 968

Query: 69   XXXXXXXXXXXTRAVFYNSVNGIILVHDLTNKKSSQNLYRWSLEVLNRDAVPTGVLVTNG 128
                        R  FY   +  +L   + + +S +NL  W  E L    +  GV     
Sbjct: 967  GQERFKSL----RTPFYRGADCCLLTFSVDSMQSFRNLSMWRKEFLYYADIQDGVT---- 812

Query: 129  DYDREQFADNQIPLLVIGTKLD 150
                        P +V+G K+D
Sbjct: 811  -----------FPFVVLGNKID 779
>12339
          Length = 578

 Score = 35.0 bits (79), Expect = 0.023,   Method: Compositional matrix adjust.
 Identities = 24/68 (35%), Positives = 32/68 (47%)
 Frame = -2

Query: 83  VFYNSVNGIILVHDLTNKKSSQNLYRWSLEVLNRDAVPTGVLVTNGDYDREQFADNQIPL 142
            FY   +  ILV+D+T  K+  +L  W  E LN+ A P          D E F     P 
Sbjct: 550 AFYRGADCCILVYDVTEXKTFDSLDSWQREFLNQ-ASPR---------DPEHF-----PF 416

Query: 143 LVIGTKLD 150
           +VIG K+D
Sbjct: 415 VVIGNKID 392
>01398
          Length = 1421

 Score = 34.7 bits (78), Expect = 0.038,   Method: Compositional matrix adjust.
 Identities = 28/96 (29%), Positives = 46/96 (47%), Gaps = 1/96 (1%)
 Frame = -2

Query: 80   TRAVFYNSVNGIILVHDLTNKKSSQNLYRWSLEVLNRDAVPTGV-LVTNGDYDREQFADN 138
            TR+ + NSV G+I+V+D+T + + +NL +W  E  N       + LV     DRE   D 
Sbjct: 1399 TRSYYRNSV-GVIIVYDITKRSTFENLKQWYEEARNHIEPHKAIFLVLGHKSDRE---DA 1232

Query: 139  QIPLLVIGTKLDQIHETKRHEVLIRTAFLAEDFNAE 174
            +      G +  ++H  K  E   ++    ED  A+
Sbjct: 1231 RQVTAREGRRFAEMHGLKFFETSAKSGHNIEDVFAQ 1124
>35581
          Length = 364

 Score = 32.3 bits (72), Expect = 0.16,   Method: Compositional matrix adjust.
 Identities = 26/113 (23%), Positives = 50/113 (44%)
 Frame = +2

Query: 8   KVLVLGDSGVGKSSLVHLLCHNQVLGNPSWTVGCSVDIRVHDYKEGTPEEKTYYIELWDX 67
           K ++LGD+GVGK+ L++ L  ++ L +P  ++  +  +       G        ++LWD 
Sbjct: 50  KCVLLGDAGVGKTCLLNRLATDKFLDSPLTSLTTASLLTTVTLTSGVMAS----VDLWDT 217

Query: 68  XXXXXXXXXXXXTRAVFYNSVNGIILVHDLTNKKSSQNLYRWSLEVLNRDAVP 120
                         + +Y     +++V+D  +K     L  W+    +R AVP
Sbjct: 218 AGQERYRSLT----SSYYRDTKAVLIVYDAEHK---LKLTDWT----DRAAVP 343
>00552
          Length = 455

 Score = 31.2 bits (69), Expect = 0.35,   Method: Compositional matrix adjust.
 Identities = 15/35 (42%), Positives = 22/35 (62%)
 Frame = -1

Query: 7   VKVLVLGDSGVGKSSLVHLLCHNQVLGNPSWTVGC 41
           +KV++LGD GVGKSSL++    N+       T+G 
Sbjct: 443 LKVVLLGDGGVGKSSLMNRFVSNKFDAQSFHTIGV 339
>26083
          Length = 432

 Score = 30.4 bits (67), Expect = 0.60,   Method: Compositional matrix adjust.
 Identities = 24/108 (22%), Positives = 45/108 (41%), Gaps = 2/108 (1%)
 Frame = +1

Query: 4   LDRVKVLVLGDSGVGKSSLVHLLCHNQVLGNPSWTVGCSVDIRVHDYKEGTP--EEKTYY 61
           L + K++ LG+  VGK+SL+    ++        T+G        D+   T   E++T  
Sbjct: 70  LRKFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGI-------DFLSKTMYLEDRTIR 228

Query: 62  IELWDXXXXXXXXXXXXXTRAVFYNSVNGIILVHDLTNKKSSQNLYRW 109
           ++LWD                 +    +  ++V+D+TN  S     +W
Sbjct: 229 LQLWDTAGQERFRSLIPS----YIRDSSVAVVVYDITNANSFHQTSKW 360
>33794
          Length = 779

 Score = 29.6 bits (65), Expect = 0.98,   Method: Compositional matrix adjust.
 Identities = 18/44 (40%), Positives = 22/44 (50%)
 Frame = -1

Query: 84  FYNSVNGIILVHDLTNKKSSQNLYRWSLEVLNRDAVPTGVLVTN 127
           +     GIILV+D+TNK S   + RW  EV         VLV N
Sbjct: 590 YSRGAQGIILVYDITNKWSFDGIDRWLKEVEEHAPGIPKVLVGN 459
>09204
          Length = 1051

 Score = 29.3 bits (64), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 22/94 (23%), Positives = 35/94 (37%), Gaps = 2/94 (2%)
 Frame = -3

Query: 83   VFYNSVNGIILVHDLTNKKSSQNLYRWSLEVLNRDAVPTGVLVTNGDYDREQFADNQIPL 142
            ++Y      IL  DLT+K S   +  W  E+                       + +  L
Sbjct: 1028 IYYRGAKAAILCFDLTDKSSFDRIRFWIGELRQH--------------------EEECKL 909

Query: 143  LVIGTKLDQIHETKRHEVLIRTA--FLAEDFNAE 174
             + GTK D +H+      + R+    LA+D  AE
Sbjct: 908  YICGTKFDLVHDDPERRAVPRSVAKALADDCMAE 807
>28329
          Length = 373

 Score = 28.9 bits (63), Expect = 2.1,   Method: Compositional matrix adjust.
 Identities = 12/27 (44%), Positives = 18/27 (66%)
 Frame = +3

Query: 5   DRVKVLVLGDSGVGKSSLVHLLCHNQV 31
           D V + ++G+  VGKSSL++ LC  Q 
Sbjct: 216 DGVHLAIIGEPNVGKSSLLNTLCQRQA 296
>33374
          Length = 489

 Score = 27.3 bits (59), Expect = 6.1,   Method: Compositional matrix adjust.
 Identities = 15/41 (36%), Positives = 23/41 (56%)
 Frame = +2

Query: 6  RVKVLVLGDSGVGKSSLVHLLCHNQVLGNPSWTVGCSVDIR 46
          + K+++LG+S VGKSSLV      Q       T+G +  +R
Sbjct: 29 QFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAF*LR 151
>05794
          Length = 952

 Score = 26.9 bits (58), Expect = 6.5,   Method: Compositional matrix adjust.
 Identities = 14/35 (40%), Positives = 18/35 (51%), Gaps = 5/35 (14%)
 Frame = -2

Query: 25  LLCHNQVLGNPSWTVG-----CSVDIRVHDYKEGT 54
           LLC N ++GN  W V      C  D + H+ KE T
Sbjct: 408 LLCINVLIGNQVWLVSFIQKYCHCDSQTHETKETT 304
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|113865979|ref|NP_032620.2| milk fat globule-EGF
factor 8 protein isoform 1 [Mus musculus]
         (463 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

12576                                                                  47   2e-05
14910                                                                  46   3e-05
05519                                                                  45   6e-05
00070                                                                  43   3e-04
30893                                                                  42   5e-04
33353                                                                  39   0.004
13514                                                                  38   0.009
09271                                                                  37   0.018
07364                                                                  34   0.12 
08743                                                                  33   0.18 
13401                                                                  32   0.66 
14158                                                                  32   0.73 
>12576
          Length = 1682

 Score = 46.6 bits (109), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 35/92 (38%), Positives = 43/92 (46%), Gaps = 3/92 (3%)
 Frame = -1

Query: 24  SGDFCDSSLCLNGGTCLTGQDNDIY---CLCPEGFTGLVCNETERGPCSPNPCYNDAKCL 80
           + D C S  C NGG C     N      C+C  GFTG  C++ E  PCS  PC N A C 
Sbjct: 953 TADPCSSKPCKNGGMCKNVVQNGALVAACVCAPGFTGATCSQ-ENNPCSSRPCKNGATCS 777

Query: 81  VTLDTQRGDIFTEYICQCPVGYSGIHCETETN 112
             L T+    F    C C  GYSG  C+ + +
Sbjct: 776 PQL-TRSSATFK---CXCKSGYSGETCDQKVD 693

 Score = 46.2 bits (108), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 37/116 (31%), Positives = 50/116 (43%), Gaps = 9/116 (7%)
 Frame = -1

Query: 9   ALCGMLLCASGLFAAS----GDFCDSSLCLNGGTC---LTGQDNDIYCLCPEGFTGLVCN 61
           AL    +CA G   A+     + C S  C NG TC   LT       C C  G++G  C+
Sbjct: 884 ALVAACVCAPGFTGATCSQENNPCSSRPCKNGATCSPQLTRSSATFKCXCKSGYSGETCD 705

Query: 62  ETE--RGPCSPNPCYNDAKCLVTLDTQRGDIFTEYICQCPVGYSGIHCETETNYYN 115
           +     G C  +PC N A C  T        +  Y C CP  Y G +CE ++ + N
Sbjct: 704 QKVDLSGACKSSPCLNGASCKPT-------AYGSYKCACPALYQGDNCEIKSEWVN 558

 Score = 43.9 bits (102), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 31/84 (36%), Positives = 38/84 (45%), Gaps = 2/84 (2%)
 Frame = -2

Query: 28   CDSSLCLNGGTCLTGQDN--DIYCLCPEGFTGLVCNETERGPCSPNPCYNDAKCLVTLDT 85
            CDS+ C NGG C   Q N     C C  GF+G+ C  +   PC  NPC N  +C      
Sbjct: 1660 CDSNPCQNGGQC---QPNGGSFTCSCVNGFSGVNC-ASRPNPCGSNPCANGGRCNAN--- 1502

Query: 86   QRGDIFTEYICQCPVGYSGIHCET 109
                    Y C C  GY G +C+T
Sbjct: 1501 -----GASYTCSCSGGYYGFNCQT 1445

 Score = 41.2 bits (95), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 35/93 (37%), Positives = 43/93 (46%), Gaps = 4/93 (4%)
 Frame = -1

Query: 19   GLFAAS-GDFCDSSLCLNGGTC---LTGQDNDIYCLCPEGFTGLVCNETERGPCSPNPCY 74
            GL  AS  D C+ + C NGG C   ++G      C C  G+ G  C +T   PC PNPC 
Sbjct: 1349 GLTCASLSDPCNPNPCRNGGVCSTEVSGGKLVSKCYCANGYEGNTC-QTLADPCKPNPCK 1173

Query: 75   NDAKCLVTLDTQRGDIFTEYICQCPVGYSGIHC 107
            N   C  T+    G   T + C C  GY G  C
Sbjct: 1172 NGGLCSTTV---VGGALT-FKCFCSAGYDGKTC 1086

 Score = 40.0 bits (92), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 31/90 (34%), Positives = 41/90 (45%), Gaps = 3/90 (3%)
 Frame = -1

Query: 26   DFCDSSLCLNGGTCLT---GQDNDIYCLCPEGFTGLVCNETERGPCSPNPCYNDAKCLVT 82
            D C S+ C NGG C +   G      C C  G+TG  C++T   PCS  PC N   C   
Sbjct: 1073 DPCSSNPCRNGGRCSSVAQGGALTFSCXCINGYTGXDCSQTAD-PCSSKPCKNGGMCKNV 897

Query: 83   LDTQRGDIFTEYICQCPVGYSGIHCETETN 112
            +  Q G +    +C    G++G  C  E N
Sbjct: 896  V--QNGALVAACVCA--PGFTGATCSQENN 819

 Score = 36.6 bits (83), Expect = 0.021,   Method: Compositional matrix adjust.
 Identities = 30/86 (34%), Positives = 36/86 (41%), Gaps = 3/86 (3%)
 Frame = -1

Query: 26   DFCDSSLCLNGGTCLT---GQDNDIYCLCPEGFTGLVCNETERGPCSPNPCYNDAKCLVT 82
            D C  + C NGG C T   G      C C  G+ G  C      PCS NPC N  +C   
Sbjct: 1199 DPCKPNPCKNGGLCSTTVVGGALTFKCFCSAGYDGKTCTGLND-PCSSNPCRNGGRC--- 1032

Query: 83   LDTQRGDIFTEYICQCPVGYSGIHCE 108
                +G   T + C C  GY+G  C 
Sbjct: 1031 SSVAQGGALT-FSCXCINGYTGXDCS 957

 Score = 36.2 bits (82), Expect = 0.030,   Method: Compositional matrix adjust.
 Identities = 27/77 (35%), Positives = 37/77 (48%)
 Frame = -1

Query: 33   CLNGGTCLTGQDNDIYCLCPEGFTGLVCNETERGPCSPNPCYNDAKCLVTLDTQRGDIFT 92
            C NGG C         C+C  G+ GL C  +   PC+PNPC N   C  + +   G + +
Sbjct: 1418 CRNGGRC-NRNGASFSCVCVGGYNGLTC-ASLSDPCNPNPCRNGGVC--STEVSGGKLVS 1251

Query: 93   EYICQCPVGYSGIHCET 109
            +  C C  GY G  C+T
Sbjct: 1250 K--CYCANGYEGNTCQT 1206
>14910
          Length = 1374

 Score = 46.2 bits (108), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 30/89 (33%), Positives = 41/89 (46%), Gaps = 6/89 (6%)
 Frame = -3

Query: 33  CLNGGTC-LTGQDNDIY---CLCPEGFTGLVCNET--ERGPCSPNPCYNDAKCLVTLDTQ 86
           C NGG C +   D  ++   C C EG++G  C++T    G CS  PC N   C  T    
Sbjct: 361 CKNGGECSVQKTDAGLFLFKCTCAEGYSGETCDQTVDTSGACSSRPCQNGGSCKPTS--- 191

Query: 87  RGDIFTEYICQCPVGYSGIHCETETNYYN 115
               +  Y C CP  Y G  CE ++ + N
Sbjct: 190 ----YGSYKCTCPALYQGDSCEIKSAWVN 116
>05519
          Length = 1164

 Score = 45.1 bits (105), Expect = 6e-05,   Method: Compositional matrix adjust.
 Identities = 29/96 (30%), Positives = 44/96 (45%), Gaps = 6/96 (6%)
 Frame = -2

Query: 26  DFCDSSLCLNGGTC---LTGQDNDIY-CLCPEGFTGLVCNET--ERGPCSPNPCYNDAKC 79
           D C SS C NG  C   +T     ++ C C +G++G  C+++    G C+  PC N   C
Sbjct: 308 DVCASSPCKNGAKCSVQVTRARLSLFKCTCAKGYSGETCDQSVDTSGACASRPCQNGGSC 129

Query: 80  LVTLDTQRGDIFTEYICQCPVGYSGIHCETETNYYN 115
             T        +  + C CP  Y G  CE ++ + N
Sbjct: 128 KPTS-------YGSFKCTCPALYQGDSCEIKSAWVN 42
>00070
          Length = 1809

 Score = 42.7 bits (99), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 30/100 (30%), Positives = 46/100 (46%), Gaps = 6/100 (6%)
 Frame = +1

Query: 22  AASGDFCDSSLCLNGGTC---LTGQDNDIY-CLCPEGFTGLVCNET--ERGPCSPNPCYN 75
           A+  D C SS C NG  C   +T     ++ C C +G++G  C+++    G C+  PC N
Sbjct: 127 ASIPDVCASSPCKNGAKCSVQVTRARLSLFKCTCAKGYSGETCDQSVDTSGACASRPCQN 306

Query: 76  DAKCLVTLDTQRGDIFTEYICQCPVGYSGIHCETETNYYN 115
              C  T        +  + C CP  Y G  CE ++ + N
Sbjct: 307 GGSCKPT-------SYGSFKCTCPALYQGDSCEIKSAWVN 405
>30893
          Length = 490

 Score = 42.0 bits (97), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 32/89 (35%), Positives = 39/89 (43%)
 Frame = +2

Query: 29  DSSLCLNGGTCLTGQDNDIYCLCPEGFTGLVCNETERGPCSPNPCYNDAKCLVTLDTQRG 88
           +  LC NGGTC     N   C C  GF G  C E +   C   PC N A C         
Sbjct: 95  EQDLCQNGGTCHN-TGNTHMCTCASGFEGSYC-ENDINECFSAPCQNGATCT-------- 244

Query: 89  DIFTEYICQCPVGYSGIHCETETNYYNLD 117
           D+   Y C C  GY G++CE     Y++D
Sbjct: 245 DLIGRYTCTCEPGYQGLNCE-----YDID 316

 Score = 38.9 bits (89), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 37/109 (33%), Positives = 46/109 (42%), Gaps = 9/109 (8%)
 Frame = +2

Query: 13  MLLCASGLFAASGDFCD-------SSLCLNGGTC--LTGQDNDIYCLCPEGFTGLVCNET 63
           M  CASG     G +C+       S+ C NG TC  L G+     C C  G+ GL C E 
Sbjct: 149 MCTCASGF---EGSYCENDINECFSAPCQNGATCTDLIGR---YTCTCEPGYQGLNC-EY 307

Query: 64  ERGPCSPNPCYNDAKCLVTLDTQRGDIFTEYICQCPVGYSGIHCETETN 112
           +   C   PC N   C         D+   Y C CP G  G+ CE + N
Sbjct: 308 DIDECHNQPCLNGGTCH--------DLVNTYKCSCPPGTQGLLCEMDEN 430

 Score = 29.6 bits (65), Expect = 2.4,   Method: Compositional matrix adjust.
 Identities = 22/57 (38%), Positives = 27/57 (47%), Gaps = 2/57 (3%)
 Frame = +2

Query: 26  DFCDSSLCLNGGTCLTGQD--NDIYCLCPEGFTGLVCNETERGPCSPNPCYNDAKCL 80
           D C +  CLNGGTC    D  N   C CP G  GL+C   E      + C+N   C+
Sbjct: 314 DECHNQPCLNGGTC---HDLVNTYKCSCPPGTQGLLCEMDENDCLFDSTCHNGGTCV 475
>33353
          Length = 559

 Score = 39.3 bits (90), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 18/45 (40%), Positives = 23/45 (51%)
 Frame = -2

Query: 64  ERGPCSPNPCYNDAKCLVTLDTQRGDIFTEYICQCPVGYSGIHCE 108
           + G C+ NPC N   C+  + T        Y CQC  GY G+HCE
Sbjct: 543 DDGVCAENPCRNGGTCIPGIGT--------YTCQCRQGYLGVHCE 433
>13514
          Length = 1135

 Score = 37.7 bits (86), Expect = 0.009,   Method: Compositional matrix adjust.
 Identities = 35/104 (33%), Positives = 46/104 (44%), Gaps = 4/104 (3%)
 Frame = -2

Query: 13  MLLCASG----LFAASGDFCDSSLCLNGGTCLTGQDNDIYCLCPEGFTGLVCNETERGPC 68
           M +C +G        + D C  + C NGGTC   +    YC CP+G TGL C+  +   C
Sbjct: 882 MCVCVNGWTGDTCTINEDDCAINPCHNGGTCHD-RVGYFYCECPQGKTGLRCHLDD--AC 712

Query: 69  SPNPCYNDAKCLVTLDTQRGDIFTEYICQCPVGYSGIHCETETN 112
             NPCY  A C      +   I    IC C  G+ G  C  + N
Sbjct: 711 DSNPCYASAGC------ETSPINGVAICTCQKGWRGADCSIDIN 598

 Score = 32.3 bits (72), Expect = 0.39,   Method: Compositional matrix adjust.
 Identities = 21/65 (32%), Positives = 30/65 (46%)
 Frame = -2

Query: 46   DIYCLCPEGFTGLVCNETERGPCSPNPCYNDAKCLVTLDTQRGDIFTEYICQCPVGYSGI 105
            D  C CP GF G  C E     C  + C+N + C+        D+   Y C+CP  Y+G 
Sbjct: 1125 DYTCTCPSGFRGRNC-ELNIDDCVNHRCHNGSTCI--------DLVENYRCECPPTYTGE 973

Query: 106  HCETE 110
             C+ +
Sbjct: 972  FCDVD 958
>09271
          Length = 1047

 Score = 37.0 bits (84), Expect = 0.018,   Method: Compositional matrix adjust.
 Identities = 29/76 (38%), Positives = 33/76 (43%)
 Frame = -2

Query: 33  CLNGGTCLTGQDNDIYCLCPEGFTGLVCNETERGPCSPNPCYNDAKCLVTLDTQRGDIFT 92
           CLNGG C+        C CP G+ G  C    R  C P PC N   CL       G+   
Sbjct: 941 CLNGGQCVAYNR----CRCPPGYRGRRCQHAFRPDCRP-PCSNGGTCL------HGN--- 804

Query: 93  EYICQCPVGYSGIHCE 108
              CQCP G SG  C+
Sbjct: 803 --RCQCPEGTSGHRCQ 762

 Score = 28.5 bits (62), Expect = 6.4,   Method: Compositional matrix adjust.
 Identities = 15/31 (48%), Positives = 17/31 (54%)
 Frame = -2

Query: 33  CLNGGTCLTGQDNDIYCLCPEGFTGLVCNET 63
           C NGGTCL G      C CPEG +G  C  +
Sbjct: 836 CSNGGTCLHGNR----CQCPEGTSGHRCQNS 756
>07364
          Length = 985

 Score = 34.3 bits (77), Expect = 0.12,   Method: Compositional matrix adjust.
 Identities = 22/60 (36%), Positives = 27/60 (45%)
 Frame = -1

Query: 49  CLCPEGFTGLVCNETERGPCSPNPCYNDAKCLVTLDTQRGDIFTEYICQCPVGYSGIHCE 108
           C CP  FTGL C       C P PC N   C +T            +C CP GY+G+ C+
Sbjct: 964 CHCPHNFTGLSCETPH---CDP-PCLNGGYCTMTA-----------VCACPYGYTGVDCQ 830

 Score = 30.0 bits (66), Expect = 1.9,   Method: Compositional matrix adjust.
 Identities = 29/100 (29%), Positives = 40/100 (40%), Gaps = 4/100 (4%)
 Frame = -1

Query: 16  CASGLFAASGDFCDSSLC----LNGGTCLTGQDNDIYCLCPEGFTGLVCNETERGPCSPN 71
           CA G     G +C++ +C    +NGG C+  +     C CP G+ G  C +     C P+
Sbjct: 769 CAKGY---KGRYCETPVCGRGCVNGGKCVAPRR----CSCPSGYRGRRCQKPR---CRPS 620

Query: 72  PCYNDAKCLVTLDTQRGDIFTEYICQCPVGYSGIHCETET 111
            C N  KC+              IC CP    G  C   T
Sbjct: 619 -CKNGGKCIA-----------PGICLCPPSLLGPRCRRHT 536

 Score = 28.9 bits (63), Expect = 4.1,   Method: Compositional matrix adjust.
 Identities = 29/85 (34%), Positives = 36/85 (42%)
 Frame = -1

Query: 26  DFCDSSLCLNGGTCLTGQDNDIYCLCPEGFTGLVCNETERGPCSPNPCYNDAKCLVTLDT 85
             CD   CLNGG C         C CP G+TG+ C      P     C+N  +C+     
Sbjct: 922 PHCDPP-CLNGGYCTM----TAVCACPYGYTGVDCQ-----PYCHKTCHNGGQCI----- 788

Query: 86  QRGDIFTEYICQCPVGYSGIHCETE 110
            R D      C+C  GY G +CET 
Sbjct: 787 -RHDR-----CRCAKGYKGRYCETP 731
>08743
          Length = 1517

 Score = 33.5 bits (75), Expect = 0.18,   Method: Compositional matrix adjust.
 Identities = 17/45 (37%), Positives = 23/45 (51%)
 Frame = -3

Query: 68   CSPNPCYNDAKCLVTLDTQRGDIFTEYICQCPVGYSGIHCETETN 112
            CSPN C     C + +D     +F    CQC  GY G+ CE +T+
Sbjct: 1059 CSPNQCGRYGDCQLFMDAT--TVFAS--CQCYAGYRGLSCEDDTH 937
>13401
          Length = 497

 Score = 31.6 bits (70), Expect = 0.66,   Method: Compositional matrix adjust.
 Identities = 25/80 (31%), Positives = 34/80 (42%), Gaps = 1/80 (1%)
 Frame = -3

Query: 30  SSLCLNGGTCLTGQDNDIYCLCPEGFTGLVCNETERGPCSPNPCYNDAKCLVTLDTQRGD 89
           + +C NGGTC T       C CP  +TG  C +     C   PC+N  +C         D
Sbjct: 441 TPVCYNGGTC-TNTAGSFTCQCPPHWTGPXCGDNIN-ECDTKPCFNAGRCQ--------D 292

Query: 90  IFTEYICQCP-VGYSGIHCE 108
             + + C C   G+ G  CE
Sbjct: 291 TVSGFTCHCSGTGFQGNRCE 232
>14158
          Length = 668

 Score = 31.6 bits (70), Expect = 0.73,   Method: Compositional matrix adjust.
 Identities = 27/90 (30%), Positives = 38/90 (42%), Gaps = 4/90 (4%)
 Frame = +3

Query: 28  CDSSLCLNGGTCLTGQD--NDIYCLCPEG-FTGLVCN-ETERGPCSPNPCYNDAKCLVTL 83
           CD++ C N  TC    D      C C +  ++G +CN   E   C+   C N   C    
Sbjct: 90  CDNNSCANNSTCTVNPDVSRGYVCDCADSNYSGDLCNINIENKSCADGLCQNPGSC---- 257

Query: 84  DTQRGDIFTEYICQCPVGYSGIHCETETNY 113
                D+   + C C  GY+G  CE+  NY
Sbjct: 258 ---TDDVNASFTCACAPGYTGSLCESPINY 338

 Score = 28.9 bits (63), Expect = 4.6,   Method: Compositional matrix adjust.
 Identities = 26/80 (32%), Positives = 34/80 (42%), Gaps = 1/80 (1%)
 Frame = +3

Query: 34  LNGGTCLTGQD-NDIYCLCPEGFTGLVCNETERGPCSPNPCYNDAKCLVTLDTQRGDIFT 92
            N GTC +     +  C C EGFTG VC +     C  N C+    C+  +D        
Sbjct: 354 CNNGTCQSNASLQNFTCECVEGFTGDVC-DANIDDCQTNTCFYGGTCVDGID-------- 506

Query: 93  EYICQCPVGYSGIHCETETN 112
            + C C  GYSG  C+   N
Sbjct: 507 HWSCICAEGYSGQWCQKMVN 566

 Score = 28.5 bits (62), Expect = 5.3,   Method: Compositional matrix adjust.
 Identities = 24/81 (29%), Positives = 35/81 (43%)
 Frame = +3

Query: 28  CDSSLCLNGGTCLTGQDNDIYCLCPEGFTGLVCNETERGPCSPNPCYNDAKCLVTLDTQR 87
           C   LC N G+C    +    C C  G+TG +C E+    C   PC N+  C      Q 
Sbjct: 222 CADGLCQNPGSCTDDVNASFTCACAPGYTGSLC-ESPINYCVDLPC-NNGTC------QS 377

Query: 88  GDIFTEYICQCPVGYSGIHCE 108
                 + C+C  G++G  C+
Sbjct: 378 NASLQNFTCECVEGFTGDVCD 440
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|134032030|ref|NP_067423.2| signal transducer and
activator of transcription interacting protein 1 [Mus musculus]
         (831 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

12806                                                                  48   2e-05
01327                                                                  47   4e-05
19863                                                                  44   3e-04
17598                                                                  44   4e-04
19949                                                                  40   0.003
02960                                                                  40   0.004
12140                                                                  39   0.012
03156                                                                  38   0.014
00561                                                                  38   0.021
19498                                                                  37   0.023
13335                                                                  37   0.029
11915                                                                  37   0.038
31384                                                                  37   0.040
22113                                                                  37   0.040
31474                                                                  37   0.041
12574                                                                  37   0.044
27465                                                                  37   0.045
29912                                                                  37   0.048
15337                                                                  36   0.076
30256                                                                  36   0.079
12841                                                                  35   0.11 
14500                                                                  35   0.13 
01768                                                                  35   0.13 
37180                                                                  35   0.13 
03387                                                                  33   0.37 
02090                                                                  33   0.39 
02948                                                                  33   0.55 
20271                                                                  32   0.91 
35607                                                                  32   0.96 
15972                                                                  32   1.2  
13278                                                                  32   1.3  
01805                                                                  31   2.0  
30727                                                                  31   2.3  
01598                                                                  31   2.6  
34005                                                                  30   3.4  
23308                                                                  30   3.9  
04358                                                                  30   5.0  
15780                                                                  29   6.1  
16105                                                                  29   6.1  
17602                                                                  29   6.7  
30295                                                                  29   9.3  
>12806
          Length = 961

 Score = 47.8 bits (112), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 30/105 (28%), Positives = 52/105 (49%), Gaps = 4/105 (3%)
 Frame = +3

Query: 608 QSLAFHTLTVTQMTFSPDDKFLLAVSRDRTWSLWK-RQDATSSEFDPFFSLFAFTNKITS 666
           ++L  H+  ++ +  S D +F L+ S D T  LW  ++ +T+S F               
Sbjct: 147 KTLTGHSHFISDLALSADSRFALSSSWDATLRLWDIKKGSTTSRFIN------------- 287

Query: 667 VHSRIIWSCDWSPDNKYFFTGSRDKKVVVW---GECKSSHNPMEH 708
            H+R + +  +SPDN+   +G RDK + +W   GECK + +   H
Sbjct: 288 -HTRDVLTVAFSPDNRQIASGGRDKNLKIWNIMGECKYTVDANAH 419

 Score = 39.3 bits (90), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 48/176 (27%), Positives = 79/176 (44%), Gaps = 10/176 (5%)
 Frame = +3

Query: 71  DGSPSNELVSGGSDNRVIHWEL------ENNQVLKSVR--LQGHEGPVCAVHAIYQSGPS 122
           DG+    L+SGG DN +I W+L      + +Q     R  L GH       H I     S
Sbjct: 33  DGATKPFLISGGRDNNIIVWDL*PKKDGDEDQTWGVPRKTLTGHS------HFISDLALS 194

Query: 123 EGEQHALIASAASDSTVRIWS-KKGSEVKYLQTLSFRDGFVLSVCLAILPGTNVPVLACG 181
              + AL  S++ D+T+R+W  KKGS        + RD  VL+V  +     +   +A G
Sbjct: 195 ADSRFAL--SSSWDATLRLWDIKKGSTTSRFINHT-RD--VLTVAFS----PDNRQIASG 347

Query: 182 DDDCRIHLY-IQQDDQFQKALSLCGHEDWIRGVEWATFGRDLFLASCSQDCLIRIW 236
             D  + ++ I  + ++   +    H DW+  V +    ++  + S S D  I++W
Sbjct: 348 GRDKNLKIWNIMGECKY--TVDANAHTDWVTCVRFHQDTKNPIVVSASNDKTIKVW 509

 Score = 30.0 bits (66), Expect = 3.7,   Method: Compositional matrix adjust.
 Identities = 21/82 (25%), Positives = 38/82 (46%), Gaps = 1/82 (1%)
 Frame = +3

Query: 561 QKLYGHGYEIVCVACN-NSKTLLASACKASQKEHAAIILWSTASWKQVQSLAFHTLTVTQ 619
           + L GH + I  +A + +S+  L+S+  A+ +      LW             HT  V  
Sbjct: 147 KTLTGHSHFISDLALSADSRFALSSSWDATLR------LWDIKKGSTTSRFINHTRDVLT 308

Query: 620 MTFSPDDKFLLAVSRDRTWSLW 641
           + FSPD++ + +  RD+   +W
Sbjct: 309 VAFSPDNRQIASGGRDKNLKIW 374
>01327
          Length = 2215

 Score = 47.0 bits (110), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 60/263 (22%), Positives = 98/263 (37%), Gaps = 44/263 (16%)
 Frame = +3

Query: 28  PGGLLAFGTSCSVVLYDPQKKVVITNLNGHTARVNCLQWIRTEDGSPSNELVSGGSDNRV 87
           PG  L+     SVVLYD Q   +     GH   +  + +     G+  N + S   D  +
Sbjct: 75  PGLCLSGSKDKSVVLYDYQNGRLEDRWTGHDREITKVCY-----GASCNGMFSASRDKTI 239

Query: 88  IHWELENNQVLKSVRLQGHEGPVCAVHAIYQSGPSEGEQHALIASAASDSTVRIWSKKGS 147
             W+  N+  ++     GH+  V A+H            + L+ S + D+TVRIW  +  
Sbjct: 240 KMWQRGNSHSIRD--FIGHDMVVTAIHL--------NTDNTLLCSGSRDNTVRIWDVETG 389

Query: 148 EVKYLQTLSFRDGFVLSVCLAILPGTNVPVLACGDDDCRIH--------------LYIQQ 193
               L+  +     V  V    LPG+++ + A  D + RI+               YIQ 
Sbjct: 390 AC--LRQNNIPQNLVTDV--KWLPGSHLIIQAGEDKEVRIYDSRTLGIVRSFTKKQYIQM 557

Query: 194 ------DDQFQKALS-----------------------LCGHEDWIRGVEWATFGRDL-F 223
                 D QF    S                         GH + I    +    +D+  
Sbjct: 558 SCDVTADGQFCLTCSNGFGGNGCEATLWQLSDGSIQNEFKGHREAIEACLFLPSNQDMTL 737

Query: 224 LASCSQDCLIRIWRLYMKPASFE 246
           +A+ S+DC +R+W ++ K    E
Sbjct: 738 IATASRDCSVRVWNMFTKECVCE 806

 Score = 35.4 bits (80), Expect = 0.083,   Method: Compositional matrix adjust.
 Identities = 24/120 (20%), Positives = 47/120 (39%), Gaps = 4/120 (3%)
 Frame = +3

Query: 589 SQKEHAAIILWSTASWKQVQSLAFHTLTVTQMTFSPDDKFLLAVSRDRTWSLWKRQDATS 648
           S  +  +++L+   + +       H   +T++ +      + + SRD+T  +W+R    S
Sbjct: 90  SGSKDKSVVLYDYQNGRLEDRWTGHDREITKVCYGASCNGMFSASRDKTIKMWQR--GNS 263

Query: 649 SEFDPFFSLFAFTNKITSVHSRIIWSCDWSPDNKYFFTGSRDKKVVVW----GECKSSHN 704
                F             H  ++ +   + DN    +GSRD  V +W    G C   +N
Sbjct: 264 HSIRDFIG-----------HDMVVTAIHLNTDNTLLCSGSRDNTVRIWDVETGACLRQNN 410

 Score = 32.3 bits (72), Expect = 0.83,   Method: Compositional matrix adjust.
 Identities = 19/79 (24%), Positives = 32/79 (40%), Gaps = 2/79 (2%)
 Frame = +3

Query: 565 GHGYEIVCVACNNSKTLLASACKA--SQKEHAAIILWSTASWKQVQSLAFHTLTVTQMTF 622
           GH  EI       +K    ++C    S      I +W   +   ++    H + VT +  
Sbjct: 159 GHDREI-------TKVCYGASCNGMFSASRDKTIKMWQRGNSHSIRDFIGHDMVVTAIHL 317

Query: 623 SPDDKFLLAVSRDRTWSLW 641
           + D+  L + SRD T  +W
Sbjct: 318 NTDNTLLCSGSRDNTVRIW 374
>19863
          Length = 502

 Score = 43.9 bits (102), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 26/72 (36%), Positives = 42/72 (58%)
 Frame = +1

Query: 77  ELVSGGSDNRVIHWELENNQVLKSVRLQGHEGPVCAVHAIYQSGPSEGEQHALIASAASD 136
           +LVSG SD  ++ W++EN   ++ +RLQGH G V  VH          +    + S ++D
Sbjct: 13  QLVSGSSDMSIVVWDVENG--VQKLRLQGHAGWVNDVHF--------SQDQCWLLSCSND 162

Query: 137 STVRIWSKKGSE 148
           +TVRIW+ + S+
Sbjct: 163 NTVRIWNIEESD 198
>17598
          Length = 875

 Score = 43.5 bits (101), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 29/104 (27%), Positives = 51/104 (49%), Gaps = 3/104 (2%)
 Frame = +1

Query: 608 QSLAFHTLTVTQMTFSPDDKFLLAVSRDRTWSLWKRQDATSSEFDPFFSLFAFTNKITSV 667
           ++L  H+  V+ ++ S D +++L+ S D T  LW  +   ++    F S           
Sbjct: 103 RTLQGHSHFVSDVSLSADSRYVLSSSWDATLRLWDIKKGNTTR--RFIS----------- 243

Query: 668 HSRIIWSCDWSPDNKYFFTGSRDKKVVVW---GECKSSHNPMEH 708
           H+R   +  +SPDN+   +G RDK + +W   GECK + +   H
Sbjct: 244 HTRDALAVAFSPDNRQIASGGRDKALKIWNTVGECKFTVDANSH 375

 Score = 35.4 bits (80), Expect = 0.098,   Method: Compositional matrix adjust.
 Identities = 35/160 (21%), Positives = 68/160 (42%), Gaps = 1/160 (0%)
 Frame = +1

Query: 78  LVSGGSDNRVIHWELENNQVLKSVRLQGHEGPVCAVHAIYQSGPSEGEQHALIASAASDS 137
           L+ GG D  +I W+L   +        G        H+ + S  S       + S++ D+
Sbjct: 10  LIXGGRDKLLIVWDLVPRKDGDEDETWGGPRRTLQGHSHFVSDVSLSADSRYVLSSSWDA 189

Query: 138 TVRIWS-KKGSEVKYLQTLSFRDGFVLSVCLAILPGTNVPVLACGDDDCRIHLYIQQDDQ 196
           T+R+W  KKG+  +   + + RD       LA+    +   +A G  D  + ++     +
Sbjct: 190 TLRLWDIKKGNTTRRFISHT-RDA------LAVAFSPDNRQIASGGRDKALKIW-NTVGE 345

Query: 197 FQKALSLCGHEDWIRGVEWATFGRDLFLASCSQDCLIRIW 236
            +  +    H+DW+  V++    +   + S S D  I++W
Sbjct: 346 CKFTVDANSHQDWVTCVKFHQDAKSPLVVSASMDKTIKVW 465

 Score = 30.0 bits (66), Expect = 4.1,   Method: Compositional matrix adjust.
 Identities = 19/80 (23%), Positives = 38/80 (47%), Gaps = 1/80 (1%)
 Frame = +1

Query: 563 LYGHGYEIVCVACN-NSKTLLASACKASQKEHAAIILWSTASWKQVQSLAFHTLTVTQMT 621
           L GH + +  V+ + +S+ +L+S+  A+ +      LW        +    HT     + 
Sbjct: 109 LQGHSHFVSDVSLSADSRYVLSSSWDATLR------LWDIKKGNTTRRFISHTRDALAVA 270

Query: 622 FSPDDKFLLAVSRDRTWSLW 641
           FSPD++ + +  RD+   +W
Sbjct: 271 FSPDNRQIASGGRDKALKIW 330
>19949
          Length = 903

 Score = 40.4 bits (93), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 34/116 (29%), Positives = 58/116 (50%), Gaps = 2/116 (1%)
 Frame = +2

Query: 29  GGLLAFGT-SCSVVLYDPQKKVVITNLNGHTARVNCLQWIRTEDGSPSNELVSGGSDNRV 87
           G   A G+  C+V L+D ++K  I    GHT  V CL++      SP    ++  S++ +
Sbjct: 29  GAYTASGSMDCNVKLWDIRRKGCIYTYKGHTGCVCCLRF------SPDGRWIASASEDGL 190

Query: 88  IH-WELENNQVLKSVRLQGHEGPVCAVHAIYQSGPSEGEQHALIASAASDSTVRIW 142
           +  W+L   ++L  ++L        AV+ I +  P E     L+AS ++D TV+ W
Sbjct: 191 VKLWDLTAGKLLTDLKLHRD-----AVNTI-EFHPHE----FLLASGSADRTVKFW 328

 Score = 34.7 bits (78), Expect = 0.17,   Method: Compositional matrix adjust.
 Identities = 30/110 (27%), Positives = 43/110 (39%), Gaps = 1/110 (0%)
 Frame = +2

Query: 588 ASQKEHAAIILWSTASWKQVQSLAFHTLTVTQMTFSPDDKFLLAVSRDRTWSLWKRQDAT 647
           AS  E   + LW   + K +  L  H   V  + F P +  L + S DRT   W  +   
Sbjct: 167 ASASEDGLVKLWDLTAGKLLTDLKLHRDAVNTIEFHPHEFLLASGSADRTVKFWDLET-- 340

Query: 648 SSEFDPFFSLFAFTNKITSVHSRIIWSCDWSPDNKYFFTGSRDK-KVVVW 696
                  F L +     T   +  I S  + PD    ++GS+D  KV  W
Sbjct: 341 -------FQLIS----TTEPEANSIRSILFHPDGVCLYSGSKDTLKVYHW 457
>02960
          Length = 1577

 Score = 40.0 bits (92), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 24/87 (27%), Positives = 44/87 (50%), Gaps = 2/87 (2%)
 Frame = +2

Query: 29  GGLLAFGTSCSVVLYDPQKKVVITNLNGHTARVNCLQWIRTEDGSPSNELVSGGSDNRVI 88
           G  L+     +V L+  + + ++T + GHT+ V C+ WI+ ++ S  +  V+G  D   +
Sbjct: 518 GXXLSGSYDNTVRLWSTKGEAIMT-IPGHTSPVKCVAWIKHDESSGVSTFVTGSHDQTAL 694

Query: 89  --HWELENNQVLKSVRLQGHEGPVCAV 113
              W+ E N+V   +  +GH   V  V
Sbjct: 695 VWQWQRETNEVDCRLSCRGHAASVDCV 775
>12140
          Length = 727

 Score = 38.5 bits (88), Expect = 0.012,   Method: Compositional matrix adjust.
 Identities = 22/65 (33%), Positives = 34/65 (52%), Gaps = 3/65 (4%)
 Frame = +2

Query: 175 VPVLACGDDDCRIHLYIQQDDQFQKALSLCGHEDWIRGVEWA---TFGRDLFLASCSQDC 231
           V     G  D  + ++ + +  + +   L GH DW+R V WA      R++ +ASCSQDC
Sbjct: 260 VKRFVSGGCDNLVKIWREDETGWVEDQKLEGHSDWVRDVAWAPSIGLPRNV-IASCSQDC 436

Query: 232 LIRIW 236
            + IW
Sbjct: 437 RVIIW 451

 Score = 38.1 bits (87), Expect = 0.015,   Method: Compositional matrix adjust.
 Identities = 31/111 (27%), Positives = 45/111 (40%), Gaps = 10/111 (9%)
 Frame = +2

Query: 55  NGHTARVNCLQWI----------RTEDGSPSNELVSGGSDNRVIHWELENNQVLKSVRLQ 104
           N HT   N + W           ++    P    VSGG DN V  W  +    ++  +L+
Sbjct: 170 NAHTIGCNAVSWAPSTAPNALFDQSARQQPVKRFVSGGCDNLVKIWREDETGWVEDQKLE 349

Query: 105 GHEGPVCAVHAIYQSGPSEGEQHALIASAASDSTVRIWSKKGSEVKYLQTL 155
           GH   V  V       PS G    +IAS + D  V IW+  GS  ++   +
Sbjct: 350 GHSDWVRDV----AWAPSIGLPRNVIASCSQDCRVIIWTNDGSSNQWTSRI 490

 Score = 30.4 bits (67), Expect = 3.1,   Method: Compositional matrix adjust.
 Identities = 55/235 (23%), Positives = 81/235 (34%), Gaps = 16/235 (6%)
 Frame = +2

Query: 152 LQTLSFRDGFVLSVCLAILPGTNVPVLACGDDDCRIHLYIQQDDQFQKALSLC-GHEDWI 210
           L   S  D  V SVC A  P     +LACG  D  + +     D    +  +   H    
Sbjct: 17  LFEYSNHDSSVNSVCFA--PHELGLILACGSSDGSLSIISTTGDGNWDSKKINNAHTIGC 190

Query: 211 RGVEWA--TFGRDLFLASCSQ-----------DCLIRIWRLYMKPASFETKDGSLRLKEN 257
             V WA  T    LF  S  Q           D L++IWR                 ++ 
Sbjct: 191 NAVSWAPSTAPNALFDQSARQQPVKRFVSGGCDNLVKIWR-----------------EDE 319

Query: 258 TFTIKDGGXXXXXXXXXXXXXXGHENWVNAVHWQPSFYKDGVLQQPVRLLSASMDKTMIL 317
           T  ++D                GH +WV  V W PS      L + V + S S D  +I+
Sbjct: 320 TGWVED------------QKLEGHSDWVRDVAWAPSIG----LPRNV-IASCSQDCRVII 448

Query: 318 WAPDEESGVWLEQV--RVGEVGGNTLGFYDCQFGENGTMIIAHAFHGALHLWKQS 370
           W  D  S  W  ++  +  +V       +   +   G ++        + LWK+S
Sbjct: 449 WTNDGSSNQWTSRILNKFSDV------VWHVSWSVTGNILAVSGGDNKVTLWKES 595
>03156
          Length = 1014

 Score = 38.1 bits (87), Expect = 0.014,   Method: Compositional matrix adjust.
 Identities = 48/219 (21%), Positives = 81/219 (36%), Gaps = 44/219 (20%)
 Frame = +1

Query: 72  GSPSNELVSGGSDNRVIHWELENNQVLKSVRLQGHEGPVCAVHAIYQSGPSEGEQHALIA 131
           G+  N + S   D  +  W+  N+  ++     GH+  V A+H            + L+ 
Sbjct: 82  GASCNGMFSASRDKTIKMWQRGNSHSIRD--FIGHDMVVTAIHL--------NTDNTLLC 231

Query: 132 SAASDSTVRIWSKKGSEVKYLQTLSFRDGFVLSVCLAILPGTNVPVLACGDDDCRIH--- 188
           S + D+TVRIW  +      L+  +     V  V    LPG+++ + A  D + RI+   
Sbjct: 232 SGSRDNTVRIWDVETGAC--LRQNNIPQNLVTDV--KWLPGSHLIIQAGEDKEVRIYDSR 399

Query: 189 -----------LYIQQ------DDQFQKALS-----------------------LCGHED 208
                       YIQ       D QF    S                         GH +
Sbjct: 400 TLGIVRSFTKKQYIQMSCDVTADGQFCLTCSNGFGGNGCEATLWQLSDGSIQNEFKGHRE 579

Query: 209 WIRGVEWATFGRDL-FLASCSQDCLIRIWRLYMKPASFE 246
            I    +    +D+  +A+ S+DC +R+W ++ K    E
Sbjct: 580 AIEACLFLPSNQDMTLIATASRDCSVRVWNMFTKECVCE 696

 Score = 32.0 bits (71), Expect = 1.0,   Method: Compositional matrix adjust.
 Identities = 19/79 (24%), Positives = 32/79 (40%), Gaps = 2/79 (2%)
 Frame = +1

Query: 565 GHGYEIVCVACNNSKTLLASACKA--SQKEHAAIILWSTASWKQVQSLAFHTLTVTQMTF 622
           GH  EI       +K    ++C    S      I +W   +   ++    H + VT +  
Sbjct: 49  GHDREI-------TKVCYGASCNGMFSASRDKTIKMWQRGNSHSIRDFIGHDMVVTAIHL 207

Query: 623 SPDDKFLLAVSRDRTWSLW 641
           + D+  L + SRD T  +W
Sbjct: 208 NTDNTLLCSGSRDNTVRIW 264
>00561
          Length = 1003

 Score = 37.7 bits (86), Expect = 0.021,   Method: Compositional matrix adjust.
 Identities = 52/202 (25%), Positives = 82/202 (40%), Gaps = 8/202 (3%)
 Frame = -3

Query: 515 IASQPFEEDELISPAFGSPQVTFQPAVLNEPPTEDHLLQNTLWPEIQKLYGHGYEIVCVA 574
           IA+ P + D +IS +     + ++         ED    N  +P+ ++LYGH + I  V 
Sbjct: 995 IATNPKDPDTIISASRDKTLIVWKLTR-----DED---TNYGYPQ-KRLYGHSHFISDVV 843

Query: 575 CNNSKTLLASACKASQKEHAAIILWSTASWKQVQSLAFHTLTVTQMTFSPDDKFLLAVSR 634
            ++      S           + LW  A+ K  +    HT  V  + FS D++ +++ SR
Sbjct: 842 LSSDGNYALSG-----SWDQTLRLWDLAAGKTTRRFEGHTKDVLSVAFSADNRQIVSGSR 678

Query: 635 DRTWSLWKRQDATSSEFDPFFSLFAFTNKITSV-----HSR-IIWSCDWSPDNKYFFTGS 688
           D+T  LW     T +E          T+ ++ V     HS  II SC W           
Sbjct: 677 DKTIKLWN----TLAECKFTIQEDGHTDWVSCVRFSPNHSNPIIVSCGW----------- 543

Query: 689 RDKKVVVW--GECKSSHNPMEH 708
            D+ V VW    CK  +N   H
Sbjct: 542 -DRTVKVWNLANCKLKNNHHGH 480

 Score = 36.2 bits (82), Expect = 0.060,   Method: Compositional matrix adjust.
 Identities = 40/172 (23%), Positives = 66/172 (38%), Gaps = 9/172 (5%)
 Frame = -3

Query: 76  NELVSGGSDNRVIHWEL----ENNQVLKSVRLQGHEGPVCAVHAIYQSGPSEGEQHALIA 131
           + ++S   D  +I W+L    + N      RL GH       H I     S    +AL  
Sbjct: 971 DTIISASRDKTLIVWKLTRDEDTNYGYPQKRLYGHS------HFISDVVLSSDGNYAL-- 816

Query: 132 SAASDSTVRIWSKKGSEVKYLQTLSFRDGFVLSVCLA-----ILPGTNVPVLACGDDDCR 186
           S + D T+R+W     +         +D  VLSV  +     I+ G+    +   +    
Sbjct: 815 SGSWDQTLRLWDLAAGKTTRRFEGHTKD--VLSVAFSADNRQIVSGSRDKTIKLWNTLAE 642

Query: 187 IHLYIQQDDQFQKALSLCGHEDWIRGVEWATFGRDLFLASCSQDCLIRIWRL 238
               IQ+D          GH DW+  V ++    +  + SC  D  +++W L
Sbjct: 641 CKFTIQED----------GHTDWVSCVRFSPNHSNPIIVSCGWDRTVKVWNL 516

 Score = 35.4 bits (80), Expect = 0.11,   Method: Compositional matrix adjust.
 Identities = 27/116 (23%), Positives = 52/116 (44%), Gaps = 2/116 (1%)
 Frame = -3

Query: 301 QQPVRLLSASMDKTMILW--APDEESGVWLEQVRVGEVGGNTLGFYDCQFGENGTMIIAH 358
           + P  ++SAS DKT+I+W    DE++     Q R   + G++    D     +G   ++ 
Sbjct: 980 KDPDTIISASRDKTLIVWKLTRDEDTNYGYPQKR---LYGHSHFISDVVLSSDGNYALSG 810

Query: 359 AFHGALHLWKQSTVNPRQWAPEIVISGHFDGVQDLMWDPEGEFIITTSTDQTTRLF 414
           ++   L LW  +     +        GH   V  + +  +   I++ S D+T +L+
Sbjct: 809 SWDQTLRLWDLAAGKTTR-----RFEGHTKDVLSVAFSADNRQIVSGSRDKTIKLW 657
>19498
          Length = 903

 Score = 37.4 bits (85), Expect = 0.023,   Method: Compositional matrix adjust.
 Identities = 23/95 (24%), Positives = 41/95 (43%), Gaps = 2/95 (2%)
 Frame = -1

Query: 604 WKQVQSLAFHTLTVTQMTFSPDDKFLLAVSRDRTWSLWKRQDATSSEFDPFFSLFAFTNK 663
           W+ V +L  H   V  + +SP D +L + S D T  +W              +   F+ +
Sbjct: 639 WRSVATLRGHAGDVLDLAWSPQDLWLASCSVDNTIVVW--------------NALKFSEQ 502

Query: 664 ITSV--HSRIIWSCDWSPDNKYFFTGSRDKKVVVW 696
           +  +  H+ ++    W P  +Y  + S DK + VW
Sbjct: 501 VAVIRGHAGMVKGVTWDPVGRYLASQSDDKTLRVW 397

 Score = 35.4 bits (80), Expect = 0.099,   Method: Compositional matrix adjust.
 Identities = 17/47 (36%), Positives = 27/47 (57%)
 Frame = -1

Query: 382 VISGHFDGVQDLMWDPEGEFIITTSTDQTTRLFAPWKKKDQKDRSQV 428
           VI GH   V+ + WDP G ++ + S D+T R+   W+  D K+ + V
Sbjct: 495 VIRGHAGMVKGVTWDPVGRYLASQSDDKTLRV---WRTSDWKEETCV 364

 Score = 34.7 bits (78), Expect = 0.17,   Method: Compositional matrix adjust.
 Identities = 45/189 (23%), Positives = 78/189 (41%), Gaps = 1/189 (0%)
 Frame = -1

Query: 50  VITNLNGHTARVNCLQWIRTEDGSPSNELVSGGSDNRVIHWELENNQVLKSVRLQGHEGP 109
           V+  ++ H   VNC++W  +E+G     L SGG D  ++ W++                 
Sbjct: 810 VLCQMDSHLGCVNCVRW--SENG---KFLASGGDDKLIMIWQISRG-------------- 688

Query: 110 VCAVHAIYQSGPSEGEQHALIASAASDSTVRIWSKKGSEVKYLQTLSFRDGFVLSVCLAI 169
                  + SG S G    ++    S +T+R                   G VL   LA 
Sbjct: 687 -------FGSGKSFGSNVTILEHWRSVATLR----------------GHAGDVLD--LAW 583

Query: 170 LPGTNVPVLACGDDDCRIHLYIQQDDQFQKALSLC-GHEDWIRGVEWATFGRDLFLASCS 228
            P  ++ + +C  D+    + +    +F + +++  GH   ++GV W   GR  +LAS S
Sbjct: 582 SP-QDLWLASCSVDNT---IVVWNALKFSEQVAVIRGHAGMVKGVTWDPVGR--YLASQS 421

Query: 229 QDCLIRIWR 237
            D  +R+WR
Sbjct: 420 DDKTLRVWR 394

 Score = 34.3 bits (77), Expect = 0.22,   Method: Compositional matrix adjust.
 Identities = 32/131 (24%), Positives = 55/131 (41%), Gaps = 1/131 (0%)
 Frame = -1

Query: 557 WPEIQKLYGHGYEIVCVACNNSKTLLASACKASQKEHAAIILWSTASW-KQVQSLAFHTL 615
           W  +  L GH  +++ +A +     LAS C         I++W+   + +QV  +  H  
Sbjct: 639 WRSVATLRGHAGDVLDLAWSPQDLWLAS-CSVDN----TIVVWNALKFSEQVAVIRGHAG 475

Query: 616 TVTQMTFSPDDKFLLAVSRDRTWSLWKRQDATSSEFDPFFSLFAFTNKITSVHSRIIWSC 675
            V  +T+ P  ++L + S D+T  +W+  D    E     S F      T V        
Sbjct: 474 MVKGVTWDPVGRYLASQSDDKTLRVWRTSDW--KEETCVKSCFKECGGTTHVL-----RL 316

Query: 676 DWSPDNKYFFT 686
           +WSPD  +  +
Sbjct: 315 NWSPDGNHVVS 283

 Score = 31.2 bits (69), Expect = 1.9,   Method: Compositional matrix adjust.
 Identities = 45/208 (21%), Positives = 73/208 (35%), Gaps = 4/208 (1%)
 Frame = -1

Query: 195 DQFQKALSLCGHEDWIRGVEWATFGRDLFLASCSQDCLIRIWRLYMKPASFETKDGSLRL 254
           + ++   +L GH   +  + W+   +DL+LASCS D  I +W              +L+ 
Sbjct: 645 EHWRSVATLRGHAGDVLDLAWSP--QDLWLASCSVDNTIVVWN-------------ALKF 511

Query: 255 KENTFTIKDGGXXXXXXXXXXXXXXGHENWVNAVHWQPSFYKDGVLQQPVRLLSASMDKT 314
            E    I+                 GH   V  V W P             L S S DKT
Sbjct: 510 SEQVAVIR-----------------GHAGMVKGVTWDPVGR---------YLASQSDDKT 409

Query: 315 MILWAPDEESGVWLEQVRV----GEVGGNTLGFYDCQFGENGTMIIAHAFHGALHLWKQS 370
           + +W   +    W E+  V     E GG T         +   ++ AHA + A       
Sbjct: 408 LRVWRTSD----WKEETCVKSCFKECGGTTHVLRLNWSPDGNHVVSAHAMNNAXP--TAQ 247

Query: 371 TVNPRQWAPEIVISGHFDGVQDLMWDPE 398
            +    W   +   GH   +  + ++P+
Sbjct: 246 IIERNGWGTSLDFVGHRKAITVVRFNPK 163

 Score = 30.0 bits (66), Expect = 3.9,   Method: Compositional matrix adjust.
 Identities = 31/141 (21%), Positives = 56/141 (39%), Gaps = 15/141 (10%)
 Frame = -1

Query: 341 LGFYDC-QFGENGTMIIAHAFHGALHLWKQS------------TVNPRQWAPEIVISGHF 387
           LG  +C ++ ENG  + +      + +W+ S                  W     + GH 
Sbjct: 786 LGCVNCVRWSENGKFLASGGDDKLIMIWQISRGFGSGKSFGSNVTILEHWRSVATLRGHA 607

Query: 388 DGVQDLMWDPEGEFIITTSTDQTTRLFAPWKKKDQKDRSQVTWHEIARPQIHGYNIKCLA 447
             V DL W P+  ++ + S D T  ++   K  +Q          +A  + H   +K + 
Sbjct: 606 GDVLDLAWSPQDLWLASCSVDNTIVVWNALKFSEQ----------VAVIRGHAGMVKGVT 457

Query: 448 M--IDRFQFVSGADEKVLRVF 466
              + R+   S +D+K LRV+
Sbjct: 456 WDPVGRY-LASQSDDKTLRVW 397

 Score = 29.6 bits (65), Expect = 5.9,   Method: Compositional matrix adjust.
 Identities = 21/94 (22%), Positives = 40/94 (42%), Gaps = 4/94 (4%)
 Frame = -1

Query: 613 HTLTVTQMTFSPDDKFLLAVSRDRTWSLWK--RQDATSSEFDPFFSLFAFTNKITSV--H 668
           H   V  + +S + KFL +   D+   +W+  R   +   F    ++      + ++  H
Sbjct: 789 HLGCVNCVRWSENGKFLASGGDDKLIMIWQISRGFGSGKSFGSNVTILEHWRSVATLRGH 610

Query: 669 SRIIWSCDWSPDNKYFFTGSRDKKVVVWGECKSS 702
           +  +    WSP + +  + S D  +VVW   K S
Sbjct: 609 AGDVLDLAWSPQDLWLASCSVDNTIVVWNALKFS 508
>13335
          Length = 863

 Score = 37.0 bits (84), Expect = 0.029,   Method: Compositional matrix adjust.
 Identities = 37/157 (23%), Positives = 59/157 (37%), Gaps = 52/157 (33%)
 Frame = +1

Query: 596 IILWSTASWKQVQSLAFHTLTVTQMTFSPDDKFLLAVSRDRTWSLWK-----------RQ 644
           I +W  A+ K V+S   H  +V  + +SP+  +L++ S +    +W            R 
Sbjct: 133 ICMWEVATQKLVRSYVGHEDSVMALAYSPNGHYLVSGSPNGDLYVWDASFGHCRHLTLRV 312

Query: 645 DA-----TSSEFDPFFS------------------------LFAFTNK------------ 663
           DA     T  EF P F                         L+ F+ +            
Sbjct: 313 DAHDLGVTCCEFSPTFGTACAENSSTCNLLLATGGKDNLIKLWTFSAQVGSPEVTLQCRD 492

Query: 664 ITSVHSRIIWSCDWSPDNKYFFTGSRDKKVVVWGECK 700
           I S HS ++ +C +SP +    +GS DK V +W   K
Sbjct: 493 ILSGHSDLVMACAFSPSSALLASGSFDKSVRLWDSVK 603

 Score = 36.6 bits (83), Expect = 0.041,   Method: Compositional matrix adjust.
 Identities = 24/87 (27%), Positives = 38/87 (43%)
 Frame = +1

Query: 610 LAFHTLTVTQMTFSPDDKFLLAVSRDRTWSLWKRQDATSSEFDPFFSLFAFTNKITSVHS 669
           L+ H+  V    FSP    L + S D++  LW              +LF+    I + HS
Sbjct: 496 LSGHSDLVMACAFSPSSALLASGSFDKSVRLWDSVKGV--------ALFS----IEACHS 639

Query: 670 RIIWSCDWSPDNKYFFTGSRDKKVVVW 696
           R +  C +S D     +GS D+ + +W
Sbjct: 640 RFVTCCAFSIDGTLLASGSMDRIIKIW 720

 Score = 32.7 bits (73), Expect = 0.56,   Method: Compositional matrix adjust.
 Identities = 70/303 (23%), Positives = 110/303 (36%), Gaps = 1/303 (0%)
 Frame = +1

Query: 67  IRTEDGSPSN-ELVSGGSDNRVIHWELENNQVLKSVRLQGHEGPVCAVHAIYQSGPSEGE 125
           IR    SPS+  LVSG  D+ +  WE+   ++++S    GHE  V A+ A   +G     
Sbjct: 70  IRVCKFSPSSSHLVSGSDDDTICMWEVATQKLVRS--YVGHEDSVMAL-AYSPNG----- 225

Query: 126 QHALIASAASDSTVRIWSKKGSEVKYLQTLSFRDGFVLSVCLAILPGTNVPVLACGDDDC 185
            H L+ S + +  + +W       ++L TL      +   C    P       AC ++  
Sbjct: 226 -HYLV-SGSPNGDLYVWDASFGHCRHL-TLRVDAHDLGVTCCEFSPTFGT---ACAENS- 384

Query: 186 RIHLYIQQDDQFQKALSLCGHEDWIRGVEWATFGRDLFLASCSQDCLIRIWRLYMKPASF 245
                           S C                +L LA+  +D LI++W       +F
Sbjct: 385 ----------------STC----------------NLLLATGGKDNLIKLW-------TF 447

Query: 246 ETKDGSLRLKENTFTIKDGGXXXXXXXXXXXXXXGHENWVNAVHWQPSFYKDGVLQQPVR 305
             + GS    E T   +D                GH + V A  + PS            
Sbjct: 448 SAQVGS---PEVTLQCRD-------------ILSGHSDLVMACAFSPS---------SAL 552

Query: 306 LLSASMDKTMILWAPDEESGVWLEQVRVGEVGGNTLGFYDCQFGENGTMIIAHAFHGALH 365
           L S S DK++ LW  D   GV L  +        T     C F  +GT++ + +    + 
Sbjct: 553 LASGSFDKSVRLW--DSVKGVALFSIEACHSRFVTC----CAFSIDGTLLASGSMDRIIK 714

Query: 366 LWK 368
           +WK
Sbjct: 715 IWK 723

 Score = 29.3 bits (64), Expect = 7.0,   Method: Compositional matrix adjust.
 Identities = 44/210 (20%), Positives = 89/210 (42%), Gaps = 10/210 (4%)
 Frame = +1

Query: 39  SVVLYDPQKKVVITNLNGHTARVNCLQWIRTEDGSPSNE-LVSGGSDNRVIHWELENNQV 97
           ++ +++   + ++ +  GH   V  L +      SP+   LVSG  +  +  W+      
Sbjct: 130 TICMWEVATQKLVRSYVGHEDSVMALAY------SPNGHYLVSGSPNGDLYVWDASFGHC 291

Query: 98  LK-SVRLQGHEGPV--CAVHAIYQSGPSEGEQ--HALIASAASDSTVRIWSKKGSEVKYL 152
              ++R+  H+  V  C     + +  +E     + L+A+   D+ +++W+         
Sbjct: 292 RHLTLRVDAHDLGVTCCEFSPTFGTACAENSSTCNLLLATGGKDNLIKLWTFSAQVGSPE 471

Query: 153 QTLSFRDGFVLS----VCLAILPGTNVPVLACGDDDCRIHLYIQQDDQFQKALSLCGHED 208
            TL  RD  +LS    + +A     +  +LA G  D  + L+         ++  C H  
Sbjct: 472 VTLQCRD--ILSGHSDLVMACAFSPSSALLASGSFDKSVRLWDSVKGVALFSIEAC-HSR 642

Query: 209 WIRGVEWATFGRDLFLASCSQDCLIRIWRL 238
           ++    ++  G    LAS S D +I+IW+L
Sbjct: 643 FVTCCAFSIDGT--LLASGSMDRIIKIWKL 726
>11915
          Length = 737

 Score = 36.6 bits (83), Expect = 0.038,   Method: Compositional matrix adjust.
 Identities = 32/113 (28%), Positives = 51/113 (45%), Gaps = 1/113 (0%)
 Frame = +1

Query: 576 NNSKTLLASACKASQKEHAAIILWSTASWKQVQSLAFHTLTVTQMTFSPDDKF-LLAVSR 634
           N+S TL+ +    S +    I LW+  + K +  +  H  TV  + F+ D+   L++ S 
Sbjct: 430 NDSSTLVLATGHVSGR----IKLWNCETGKLLIEMMDHKATVHDLHFAADNSLCLMSASH 597

Query: 635 DRTWSLWKRQDATSSEFDPFFSLFAFTNKITSVHSRIIWSCDWSPDNKYFFTG 687
           D T  LW+  D    + D    L   TN      ++  +SC WS D +Y  T 
Sbjct: 598 DGTVKLWEFDD----QGDCNMYLTLRTN------AKHAFSCRWSHDRRYVATA 726
>31384
          Length = 474

 Score = 36.6 bits (83), Expect = 0.040,   Method: Compositional matrix adjust.
 Identities = 28/109 (25%), Positives = 49/109 (44%)
 Frame = -1

Query: 34  FGTSCSVVLYDPQKKVVITNLNGHTARVNCLQWIRTEDGSPSNELVSGGSDNRVIHWELE 93
           FG++      +P K   +T+    +  V+CL++  +    PS  L+SG  DN+V  WE++
Sbjct: 342 FGSTAPAANTNPMKDFEVTSPPDDS--VSCLKF--SPGALPSTFLISGSWDNKVSCWEVQ 175

Query: 94  NNQVLKSVRLQGHEGPVCAVHAIYQSGPSEGEQHALIASAASDSTVRIW 142
            +        Q H GPV  V           +    + +A+ D T ++W
Sbjct: 174 QSGQTIPKAQQTHTGPVLDVD--------WSDDGTKVFTASCDKTAKVW 52

 Score = 29.6 bits (65), Expect = 4.7,   Method: Compositional matrix adjust.
 Identities = 24/84 (28%), Positives = 34/84 (40%), Gaps = 3/84 (3%)
 Frame = -1

Query: 616 TVTQMTFSP---DDKFLLAVSRDRTWSLWKRQDATSSEFDPFFSLFAFTNKITSVHSRII 672
           +V+ + FSP      FL++ S D   S W+ Q +  +             K    H+  +
Sbjct: 270 SVSCLKFSPGALPSTFLISGSWDNKVSCWEVQQSGQT-----------IPKAQQTHTGPV 124

Query: 673 WSCDWSPDNKYFFTGSRDKKVVVW 696
              DWS D    FT S DK   VW
Sbjct: 123 LDVDWSDDGTKVFTASCDKTAKVW 52
>22113
          Length = 614

 Score = 36.6 bits (83), Expect = 0.040,   Method: Compositional matrix adjust.
 Identities = 26/87 (29%), Positives = 38/87 (43%)
 Frame = +3

Query: 610 LAFHTLTVTQMTFSPDDKFLLAVSRDRTWSLWKRQDATSSEFDPFFSLFAFTNKITSVHS 669
           L  H   V  + F+   K+ ++  +D   + W+     S           F +K TS   
Sbjct: 90  LHLHESCVLSLRFATCGKWFVSTGKDNLLNAWRTPYGAS----------IFQSKETSS-- 233

Query: 670 RIIWSCDWSPDNKYFFTGSRDKKVVVW 696
             + SCD S D+KY  TGS DKK  V+
Sbjct: 234 --VLSCDISTDDKYIVTGSGDKKATVY 308
>31474
          Length = 403

 Score = 36.6 bits (83), Expect = 0.041,   Method: Compositional matrix adjust.
 Identities = 34/112 (30%), Positives = 53/112 (47%), Gaps = 3/112 (2%)
 Frame = -3

Query: 559 EIQKLYGHGYEIVCVACNNSKTLLASACKASQKEHAAIILWSTA--SWKQVQSLA-FHTL 615
           E+  L  H     CVA N + TLLAS C + +     I +W     +W    +L   HT 
Sbjct: 329 EVCCLSAHDEHAWCVAWNPTGTLLAS-CGSDK----IIKIWGKEGDNWVCKSTLTDAHTR 165

Query: 616 TVTQMTFSPDDKFLLAVSRDRTWSLWKRQDATSSEFDPFFSLFAFTNKITSV 667
           TV  + +SP   +L + S D T ++W R+     EF+   +L    N++ +V
Sbjct: 164 TVRSLGWSPCGNYLSSASFDATTAVWSRK---GGEFECIATLEGHENEVKAV 18

 Score = 34.3 bits (77), Expect = 0.21,   Method: Compositional matrix adjust.
 Identities = 26/89 (29%), Positives = 43/89 (48%), Gaps = 1/89 (1%)
 Frame = -3

Query: 129 LIASAASDSTVRIWSKKGSEVKYLQTLSFRDGFVLSV-CLAILPGTNVPVLACGDDDCRI 187
           L+AS  SD  ++IW K+G       TL+  D    +V  L   P  N   L+    D   
Sbjct: 263 LLASCGSDKIIKIWGKEGDNWVCKSTLT--DAHTRTVRSLGWSPCGNY--LSSASFDATT 96

Query: 188 HLYIQQDDQFQKALSLCGHEDWIRGVEWA 216
            ++ ++  +F+   +L GHE+ ++ V WA
Sbjct: 95  AVWSRKGGEFECIATLEGHENEVKAVAWA 9

 Score = 32.7 bits (73), Expect = 0.58,   Method: Compositional matrix adjust.
 Identities = 33/117 (28%), Positives = 52/117 (44%), Gaps = 2/117 (1%)
 Frame = -3

Query: 54  LNGHTARVNCLQWIRTEDGSPSNELV-SGGSDNRVIHWELE-NNQVLKSVRLQGHEGPVC 111
           L+ H     C+ W      +P+  L+ S GSD  +  W  E +N V KS     H     
Sbjct: 317 LSAHDEHAWCVAW------NPTGTLLASCGSDKIIKIWGKEGDNWVCKSTLTDAH----- 171

Query: 112 AVHAIYQSGPSEGEQHALIASAASDSTVRIWSKKGSEVKYLQTLSFRDGFVLSVCLA 168
               +   G S    +  ++SA+ D+T  +WS+KG E + + TL   +  V +V  A
Sbjct: 170 -TRTVRSLGWSPCGNY--LSSASFDATTAVWSRKGGEFECIATLEGHENEVKAVAWA 9

 Score = 32.3 bits (72), Expect = 0.76,   Method: Compositional matrix adjust.
 Identities = 22/107 (20%), Positives = 44/107 (41%)
 Frame = -3

Query: 590 QKEHAAIILWSTASWKQVQSLAFHTLTVTQMTFSPDDKFLLAVSRDRTWSLWKRQDATSS 649
           ++ HA + +   A+ ++V  L+ H      + ++P    L +   D+   +W ++     
Sbjct: 368 RRTHAKMAM---ATLEEVCCLSAHDEHAWCVAWNPTGTLLASCGSDKIIKIWGKEGDN-- 204

Query: 650 EFDPFFSLFAFTNKITSVHSRIIWSCDWSPDNKYFFTGSRDKKVVVW 696
                   +   + +T  H+R + S  WSP   Y  + S D    VW
Sbjct: 203 --------WVCKSTLTDAHTRTVRSLGWSPCGNYLSSASFDATTAVW 87
>12574
          Length = 521

 Score = 36.6 bits (83), Expect = 0.044,   Method: Composition-based stats.
 Identities = 23/101 (22%), Positives = 42/101 (41%)
 Frame = +3

Query: 588 ASQKEHAAIILWSTASWKQVQSLAFHTLTVTQMTFSPDDKFLLAVSRDRTWSLWKRQDAT 647
           AS      I +W     K  +++A H L ++ + +S D K L + S D+T  +W+     
Sbjct: 234 ASSSADKLIKIWGAYDGKFEKTIAGHKLGLSDVAWSSDSKLLCSASDDKTLKIWEFSTGK 413

Query: 648 SSEFDPFFSLFAFTNKITSVHSRIIWSCDWSPDNKYFFTGS 688
                          K    HS  ++ C+++P +    +GS
Sbjct: 414 CM-------------KTLKGHSNYVFCCNFNPQSNLIVSGS 497

 Score = 35.0 bits (79), Expect = 0.11,   Method: Composition-based stats.
 Identities = 28/108 (25%), Positives = 48/108 (44%), Gaps = 8/108 (7%)
 Frame = +3

Query: 600 STASWKQVQSLAF----HTLTVTQMTFSPDDKFLLAVSRDRTWSLWKRQDATSSEFDPFF 655
           S+A+ K   +L F    HT  ++ + FSP+  +L + S D+   +W   D    +F+   
Sbjct: 132 SSATQKPTYTLKFTLAGHTKALSAVKFSPNGDWLASSSADKLIKIWGAYDG---KFE--- 293

Query: 656 SLFAFTNKITSVHSRIIWSCDWSPDNKYFFTGSRDKKVVVW----GEC 699
                  K  + H   +    WS D+K   + S DK + +W    G+C
Sbjct: 294 -------KTIAGHKLGLSDVAWSSDSKLLCSASDDKTLKIWEFSTGKC 416
>27465
          Length = 658

 Score = 36.6 bits (83), Expect = 0.045,   Method: Compositional matrix adjust.
 Identities = 27/91 (29%), Positives = 39/91 (42%), Gaps = 3/91 (3%)
 Frame = -1

Query: 559 EIQKLYGHGYEIVCVACNN---SKTLLASACKASQKEHAAIILWSTASWKQVQSLAFHTL 615
           E+  L GH   +  +A NN    K +  S  K  +       LWSTA  K   +L  HT 
Sbjct: 259 ELHTLEGHRNVVYAIAFNNPFGDKVITGSFDKTCK-------LWSTADGKCYHTLRGHTA 101

Query: 616 TVTQMTFSPDDKFLLAVSRDRTWSLWKRQDA 646
            +  ++F+P    +   S D T  LW  + A
Sbjct: 100 EIVCVSFNPSSTLIATGSMDTTCRLWDVEKA 8

 Score = 29.3 bits (64), Expect = 6.2,   Method: Compositional matrix adjust.
 Identities = 41/188 (21%), Positives = 71/188 (37%), Gaps = 6/188 (3%)
 Frame = -1

Query: 515 IASQPFEEDELISPAFGSPQVTFQPAVLNEPPTEDHLLQNTLWPEIQKLYGHGYEIVCVA 574
           +  +  E+++LI+P+       +  A     P +DH          + L  H   +  VA
Sbjct: 502 VVQEIAEKEQLITPSKQEHVKNWCFACRKTRPKDDHHFY-----LFKVLRAHILPLTNVA 338

Query: 575 CNNSKTLLASA-----CKASQKEHAAIILWSTASWKQVQSLAFHTLTVTQMTF-SPDDKF 628
            N S +   +      CK          +W TAS +++ +L  H   V  + F +P    
Sbjct: 337 FNKSGSSFITGSYDRTCK----------IWDTASAEELHTLEGHRNVVYAIAFNNPFGDK 188

Query: 629 LLAVSRDRTWSLWKRQDATSSEFDPFFSLFAFTNKITSVHSRIIWSCDWSPDNKYFFTGS 688
           ++  S D+T  LW   D        + +L   T +I  V         ++P +    TGS
Sbjct: 187 VITGSFDKTCKLWSTADGKC-----YHTLRGHTAEIVCV--------SFNPSSTLIATGS 47

Query: 689 RDKKVVVW 696
            D    +W
Sbjct: 46  MDTTCRLW 23
>29912
          Length = 510

 Score = 36.6 bits (83), Expect = 0.048,   Method: Compositional matrix adjust.
 Identities = 40/146 (27%), Positives = 62/146 (42%), Gaps = 4/146 (2%)
 Frame = +3

Query: 15  PNRVRGALSWNTGPGGLLAFGTSCS-VVLYDPQKKVVITNLNGHTARVNCLQWIRTEDGS 73
           P    GA+SW    G  LA GTS   V ++D  ++  +  + GH ARV  L W       
Sbjct: 6   PEEYIGAVSW-IKEGNYLALGTSTGEVQVWDVTQQKKLRTMAGHAARVGSLSW------- 161

Query: 74  PSNELVSGGSDNRVIHWELENNQVLKSVRLQGHEGPVCAVHAIYQSGPSEGEQHALIASA 133
            ++ +VS GS +  IH           VR+  H     + H+    G         +AS 
Sbjct: 162 -NSFIVSSGSRSGNIH--------HHDVRVADHHVGTLSGHSQEVCGLRWSPDGKYLASG 314

Query: 134 ASDSTVRIWSKK---GSEVKYLQTLS 156
           A+D+ + +W  +   G+  + L T S
Sbjct: 315 ANDNLLCVWPAQVTGGNSTQPLHTFS 392

 Score = 33.5 bits (75), Expect = 0.39,   Method: Compositional matrix adjust.
 Identities = 19/65 (29%), Positives = 31/65 (47%)
 Frame = +3

Query: 666 SVHSRIIWSCDWSPDNKYFFTGSRDKKVVVWGECKSSHNPMEHPIRPCSSILDVGSSVTA 725
           S HS+ +    WSPD KY  +G+ D  + VW    +  N  +    P  +     ++V A
Sbjct: 249 SGHSQEVCGLRWSPDGKYLASGANDNLLCVWPAQVTGGNSTQ----PLHTFSQHQAAVKA 416

Query: 726 VSVCP 730
           ++ CP
Sbjct: 417 LAWCP 431
>15337
          Length = 860

 Score = 35.8 bits (81), Expect = 0.076,   Method: Compositional matrix adjust.
 Identities = 21/83 (25%), Positives = 34/83 (40%)
 Frame = -1

Query: 614 TLTVTQMTFSPDDKFLLAVSRDRTWSLWKRQDATSSEFDPFFSLFAFTNKITSVHSRIIW 673
           T  +++  FSP  ++L  V +D    ++             ++       + S    ++ 
Sbjct: 329 TGAISEFAFSPCSRYLAVVGQDGHLRVFN------------YNSMELIGTMKSYFGGLLC 186

Query: 674 SCDWSPDNKYFFTGSRDKKVVVW 696
            C WSPD KY  TG  D  V VW
Sbjct: 185 VC-WSPDGKYIVTGGEDDLVTVW 120
>30256
          Length = 961

 Score = 35.8 bits (81), Expect = 0.079,   Method: Compositional matrix adjust.
 Identities = 33/117 (28%), Positives = 53/117 (45%)
 Frame = +3

Query: 39  SVVLYDPQKKVVITNLNGHTARVNCLQWIRTEDGSPSNELVSGGSDNRVIHWELENNQVL 98
           +V ++DP     +  L GHT RV  LQ+    DG     +VSG  D  +  W++   +++
Sbjct: 345 TVRVWDPDTASCLHTLQGHTNRVYSLQF----DGV---YVVSGSLDTSIRVWDVRCGKLV 503

Query: 99  KSVRLQGHEGPVCAVHAIYQSGPSEGEQHALIASAASDSTVRIWSKKGSEVKYLQTL 155
            +  L GH+     +            +  L+ S  +DSTV++W       K LQTL
Sbjct: 504 HT--LMGHQSLTSGLEL----------KDNLLVSGNADSTVKVWDVHTG--KCLQTL 632

 Score = 32.0 bits (71), Expect = 0.99,   Method: Compositional matrix adjust.
 Identities = 50/204 (24%), Positives = 82/204 (40%), Gaps = 7/204 (3%)
 Frame = +3

Query: 42  LYDPQKKVVITNLNGHTARVNCLQWIRTEDGSPSNELVSGGSDNRVIHWELENNQVLKSV 101
           ++D +    +  L GH A V C+Q+    DG     +VSG  D  V  W+ +    L + 
Sbjct: 234 VWDIESGHCLNVLLGHMAAVRCVQY----DG---KRVVSGAXDYTVRVWDPDTASCLHT- 389

Query: 102 RLQGHEGPVCAVH--AIYQSGPSEGEQHALIASAASDSTVRIWSKKGSEVKYLQTL---- 155
            LQGH   V ++    +Y            + S + D+++R+W  +    K + TL    
Sbjct: 390 -LQGHTNRVYSLQFDGVY------------VVSGSLDTSIRVWDVRCG--KLVHTLMGHQ 524

Query: 156 SFRDGFVLSVCLAILPGTNVPVLACGDDDCRIHLYIQQDDQFQKAL-SLCGHEDWIRGVE 214
           S   G  L   L          L  G+ D  + ++   D    K L +L G       V 
Sbjct: 525 SLTSGLELKDNL----------LVSGNADSTVKVW---DVHTGKCLQTLLGPNKHRSAVT 665

Query: 215 WATFGRDLFLASCSQDCLIRIWRL 238
              F +  F+ +CS D  +++W L
Sbjct: 666 CLQFNKK-FVVTCSDDGTVKLWDL 734
>12841
          Length = 1364

 Score = 35.0 bits (79), Expect = 0.11,   Method: Compositional matrix adjust.
 Identities = 47/185 (25%), Positives = 80/185 (43%), Gaps = 23/185 (12%)
 Frame = +1

Query: 75  SNELVSGGSDNRVIHWELENNQ---VLKSVRLQG-HEGPVCAVHAIYQSGPSEGEQHALI 130
           +N L +G  D  V  + + +     +L +    G H GPV  +  I +   S  E+  ++
Sbjct: 592 ANILAAGYYDGGVAIYNVRSTSDEPILDNQETHGKHLGPVWQIQWIEKERGSGEERAEVL 771

Query: 131 ASAASDSTVRIWS-KKGSE---VKYLQTLSFR----------DGFVL----SVCLAILPG 172
            S ++D  V  WS +KG E   +  L+ L  R          + F+      +C      
Sbjct: 772 ISISTDGRVTQWSIRKGFESNNIMRLKKLPTRMAGKAREKKGEAFISRHAGGLCFD-FHS 948

Query: 173 TNVPVLACGDDDCRIH-LYIQQDDQFQKALSLCGHEDWIRGVEWATFGRDLFLASCSQDC 231
            ++ V   G ++  IH      ++Q+ +  S  GH   +  + W+ F  D+FL SCS D 
Sbjct: 949 RDLNVYLAGTEEGYIHKCSCSYNEQYLETYS--GHTAPVYHIRWSPFVSDIFL-SCSADW 1119

Query: 232 LIRIW 236
            IR+W
Sbjct: 1120SIRLW 1134
>14500
          Length = 1238

 Score = 35.0 bits (79), Expect = 0.13,   Method: Compositional matrix adjust.
 Identities = 16/47 (34%), Positives = 25/47 (53%)
 Frame = +3

Query: 596 IILWSTASWKQVQSLAFHTLTVTQMTFSPDDKFLLAVSRDRTWSLWK 642
           +I+W   +  +V  L  HT  V  M  SPD + +++ + D T  LWK
Sbjct: 411 LIIWKYPAMSRVAELTGHTARVLHMAMSPDGETVVSAAADETLRLWK 551

 Score = 31.6 bits (70), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 13/31 (41%), Positives = 18/31 (58%)
 Frame = +2

Query: 666 SVHSRIIWSCDWSPDNKYFFTGSRDKKVVVW 696
           S HS+ +    WSPD KY  +G+ D  + VW
Sbjct: 50  SGHSQEVCGLRWSPDGKYLASGANDNLLCVW 142

 Score = 30.0 bits (66), Expect = 4.2,   Method: Compositional matrix adjust.
 Identities = 19/77 (24%), Positives = 37/77 (48%), Gaps = 1/77 (1%)
 Frame = +3

Query: 350 ENGTMIIAHAF-HGALHLWKQSTVNPRQWAPEIVISGHFDGVQDLMWDPEGEFIITTSTD 408
           E+  +I +H F    L +WK   +     +    ++GH   V  +   P+GE +++ + D
Sbjct: 366 EHRELISSHGFAQNQLIIWKYPAM-----SRVAELTGHTARVLHMAMSPDGETVVSAAAD 530

Query: 409 QTTRLFAPWKKKDQKDR 425
           +T RL+  +    +K R
Sbjct: 531 ETLRLWKCFTVDKEKKR 581
>01768
          Length = 1424

 Score = 35.0 bits (79), Expect = 0.13,   Method: Compositional matrix adjust.
 Identities = 21/63 (33%), Positives = 30/63 (47%), Gaps = 3/63 (4%)
 Frame = +3

Query: 184 DCRIHLYIQQDDQ---FQKALSLCGHEDWIRGVEWATFGRDLFLASCSQDCLIRIWRLYM 240
           DC   +YI Q        +  S   H D +  V+W+    ++F ASCS D  +RIW    
Sbjct: 759 DCTGAIYISQPSSSGWTTEKSSYAAHTDSVEDVQWSPNEGNVF-ASCSVDRTLRIWNTQQ 935

Query: 241 KPA 243
           KP+
Sbjct: 936 KPS 944

 Score = 34.3 bits (77), Expect = 0.21,   Method: Compositional matrix adjust.
 Identities = 37/158 (23%), Positives = 65/158 (41%), Gaps = 2/158 (1%)
 Frame = +3

Query: 600 STASWK-QVQSLAFHTLTVTQMTFSPDDKFLLA-VSRDRTWSLWKRQDATSSEFDPFFSL 657
           S++ W  +  S A HT +V  + +SP++  + A  S DRT  +W  Q   S         
Sbjct: 792 SSSGWTTEKSSYAAHTDSVEDVQWSPNEGNVFASCSVDRTLRIWNTQQKPSK-------- 947

Query: 658 FAFTNKITSVHSRIIWSCDWSPDNKYFFTGSRDKKVVVWGECKSSHNPMEHPIRPCSSIL 717
            A    +   HSR I   +W+P  K+      D  ++   + +   N    P+   +S  
Sbjct: 948 -ANVLTVPEAHSRDINVINWNPIEKHLLASGGDDGIIKIWDLRMFRN---KPVSAQASFK 1115

Query: 718 DVGSSVTAVSVCPVLNPAQRYIVAIGLESGKICIYSWN 755
                VT++      NP    ++A   E  +I I+ ++
Sbjct: 1116LHSQPVTSLE----WNPQDSSVLAASGEDDQITIWDFS 1217
>37180
          Length = 681

 Score = 35.0 bits (79), Expect = 0.13,   Method: Compositional matrix adjust.
 Identities = 30/112 (26%), Positives = 51/112 (45%), Gaps = 3/112 (2%)
 Frame = +1

Query: 54  LNGHTARVNCLQWIRTEDGSPSNELVSGGSDNRVIH-WELENNQVLKSVRLQGHEGPVCA 112
           LNGH   ++ +         P+  LV   S +     W+  ++ +L +V  QGH  PV +
Sbjct: 7   LNGHDQELSDVH------AHPTQRLVVTSSKDMTFRLWDFRDSALLVNV-FQGHTQPVTS 165

Query: 113 VHAIYQSGPSEGEQHALIASAASDSTVRIWSKKG--SEVKYLQTLSFRDGFV 162
             A++ SG         + S + D TVR+W  +   S +  ++T S  + FV
Sbjct: 166 --AVFASGDK-------VVSGSDDRTVRVWDMRNMRSPIATIRTDSAVNRFV 294
>03387
          Length = 1891

 Score = 33.5 bits (75), Expect = 0.37,   Method: Compositional matrix adjust.
 Identities = 30/99 (30%), Positives = 48/99 (48%), Gaps = 4/99 (4%)
 Frame = +1

Query: 54  LNGHTARVNCLQWIRTEDGSPSNE--LVSGGSDNRVIHWELENNQVLKSVRLQGHEGPVC 111
           ++ HTA VNCL +      +P +E  L +G +D  V  W+L N + LK    + H+  + 
Sbjct: 637 VDAHTAEVNCLSF------NPYSEFILATGSADKTVALWDLRNLK-LKLHSFESHKDEIF 795

Query: 112 AVHAIYQSGPSEGEQHALIASAASDSTVRIW--SKKGSE 148
            V    Q  P       ++AS+ +D  + +W  SK G E
Sbjct: 796 QV----QWSP---HNETILASSGTDRRLHVWDLSKIGEE 891
>02090
          Length = 1841

 Score = 33.5 bits (75), Expect = 0.39,   Method: Compositional matrix adjust.
 Identities = 24/88 (27%), Positives = 39/88 (44%), Gaps = 1/88 (1%)
 Frame = -3

Query: 610  LAFHTLTVTQMTFSPDDKFLLAVSRDRTWSLWKRQDATSSEFDPF-FSLFAFTNKITSVH 668
            L  H   V  + F+   K+ ++  +D   + W+          P+  S+F       S  
Sbjct: 1266 LHLHESCVLSLKFAYCGKWFVSTGKDNLLNAWRT---------PYGASIF------QSKE 1132

Query: 669  SRIIWSCDWSPDNKYFFTGSRDKKVVVW 696
            S  + SCD + D+KY  TGS DKK  ++
Sbjct: 1131 SSSVLSCDIAADDKYIVTGSGDKKATLY 1048

 Score = 31.6 bits (70), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 22/76 (28%), Positives = 37/76 (48%), Gaps = 4/76 (5%)
 Frame = -3

Query: 28   PGGLLAFGTSCS---VVLYDPQKKVVITNLNGHTARVNCLQWIRTEDGSP-SNELVSGGS 83
            P G + F + CS   + ++D   + ++    GHT   +C+      D SP   +L +GG 
Sbjct: 1596 PDGKVCF-SCCSDGNIAVWDLHNQTLVRQFQGHTDGASCI------DISPDGTKLWTGGL 1438

Query: 84   DNRVIHWELENNQVLK 99
            DN V  W+L   + L+
Sbjct: 1437 DNTVRSWDLREGRQLQ 1390
>02948
          Length = 1207

 Score = 32.7 bits (73), Expect = 0.55,   Method: Compositional matrix adjust.
 Identities = 33/127 (25%), Positives = 57/127 (44%), Gaps = 1/127 (0%)
 Frame = -2

Query: 570 IVCVACNNSKTLLASACKASQKEHAAIILWSTASWKQVQSLA-FHTLTVTQMTFSPDDKF 628
             CV+C+ +   +A+   AS K       W+    K V S++ +H+L VT + F+P+   
Sbjct: 747 FTCVSCHPTDVCIATG-HASGK---ITFWWNFDQDKTVLSVSHWHSLPVTCLAFTPEGSC 580

Query: 629 LLAVSRDRTWSLWKRQDATSSEFDPFFSLFAFTNKITSVHSRIIWSCDWSPDNKYFFTGS 688
           LL+   + T   W+  ++   EF P             +H+ ++     SPD  +F TG 
Sbjct: 579 LLSGGHECTLVRWQ-MNSEHKEFLPRLG--------APLHNIVV-----SPDGVFFVTGH 442

Query: 689 RDKKVVV 695
            D  + V
Sbjct: 441 SDNVLQV 421
>20271
          Length = 567

 Score = 32.3 bits (72), Expect = 0.91,   Method: Compositional matrix adjust.
 Identities = 32/150 (21%), Positives = 64/150 (42%)
 Frame = -1

Query: 41  VLYDPQKKVVITNLNGHTARVNCLQWIRTEDGSPSNELVSGGSDNRVIHWELENNQVLKS 100
           +L  PQ  + + +    +    C  ++  +    +N  + G  +  V       ++   +
Sbjct: 471 MLSQPQDSMELQHKQSKSVAATCFSFLSGD----ANNFIVGSEECLVYSASRHGSKAGIN 304

Query: 101 VRLQGHEGPVCAVHAIYQSGPSEGEQHALIASAASDSTVRIWSKKGSEVKYLQTLSFRDG 160
              +GH+GP+ A+   + +G  +     L AS   D TV++W+ K  E KY+ +      
Sbjct: 303 EAYEGHQGPITAIDTHHAAGQIDFSPFFLTASF--DWTVKLWNIK--EQKYVCSFEDNSD 136

Query: 161 FVLSVCLAILPGTNVPVLACGDDDCRIHLY 190
           +V  V  +    TN  + +C D   R+ L+
Sbjct: 135 YVSDVQWS---PTNPALFSCVDIMGRLDLW 55
>35607
          Length = 475

 Score = 32.0 bits (71), Expect = 0.96,   Method: Compositional matrix adjust.
 Identities = 24/88 (27%), Positives = 39/88 (44%), Gaps = 1/88 (1%)
 Frame = +2

Query: 610 LAFHTLTVTQMTFSPDDKFLLAVSRDRTWSLWKRQDATSSEFDPF-FSLFAFTNKITSVH 668
           L  H   V  + F+   K+ ++  +D   + W+          P+  S+F       S  
Sbjct: 212 LHLHESCVLSLKFAYCGKWFVSTGKDNLLNAWRT---------PYGASIFQ------SKE 346

Query: 669 SRIIWSCDWSPDNKYFFTGSRDKKVVVW 696
           S  + SCD + D+KY  TGS DKK  ++
Sbjct: 347 SSSVLSCDIAADDKYIVTGSGDKKATLY 430
>15972
          Length = 1069

 Score = 32.0 bits (71), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 15/35 (42%), Positives = 19/35 (54%)
 Frame = +3

Query: 379 PEIVISGHFDGVQDLMWDPEGEFIITTSTDQTTRL 413
           PE   SGH   V+ L   P G+  +T S D+T RL
Sbjct: 213 PERTFSGHKGPVRHLAVHPSGKLTLTVSQDRTLRL 317
>13278
          Length = 870

 Score = 31.6 bits (70), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 25/77 (32%), Positives = 34/77 (44%), Gaps = 1/77 (1%)
 Frame = +1

Query: 621 TFSPDDKFLLA-VSRDRTWSLWKRQDATSSEFDPFFSLFAFTNKITSVHSRIIWSCDWSP 679
           T +P+   +LA  S D T  LW        E +    L   T      H   ++S  +SP
Sbjct: 94  TSNPNTSLILASASFDSTVRLW--------EVERGLCLHTLTK-----HQEPVYSVAFSP 234

Query: 680 DNKYFFTGSRDKKVVVW 696
           D KY  +GS DK V +W
Sbjct: 235 DGKYLASGSFDKCVHIW 285

 Score = 31.6 bits (70), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 17/49 (34%), Positives = 25/49 (51%), Gaps = 5/49 (10%)
 Frame = +1

Query: 604 WKQVQSLAFHTLT-----VTQMTFSPDDKFLLAVSRDRTWSLWKRQDAT 647
           W+  + L  HTLT     V  + FSPD K+L + S D+   +W  Q  +
Sbjct: 157 WEVERGLCLHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNVQTGS 303
>01805
          Length = 2124

 Score = 31.2 bits (69), Expect = 2.0,   Method: Compositional matrix adjust.
 Identities = 27/97 (27%), Positives = 46/97 (47%), Gaps = 2/97 (2%)
 Frame = -1

Query: 608 QSLAFHTLTVTQMTFSPDDKFLLA-VSRDRTWSLWKRQDATSSEFDPFFSLFAFTNKITS 666
           +S+  HT  V  ++++ + + +LA  S D T +LW   +   +          FT     
Sbjct: 594 ESVTGHTQAVLDLSWNRNARHVLASASADTTVALWDLSEGKMA--------MNFTQ---- 451

Query: 667 VHSRIIWSCDWSP-DNKYFFTGSRDKKVVVWGECKSS 702
            HSR +  C+W P + +   TGS D  V V  +C+S+
Sbjct: 450 -HSREVQCCNWHPQEEQTLLTGSFDNTVKV-VDCRSA 346
>30727
          Length = 402

 Score = 30.8 bits (68), Expect = 2.3,   Method: Compositional matrix adjust.
 Identities = 19/82 (23%), Positives = 38/82 (46%), Gaps = 5/82 (6%)
 Frame = +1

Query: 77  ELVSGGSDNRVIHWELENNQVLKSVRLQGHEGPVCAVHAIYQSGP-----SEGEQHALIA 131
           E++SGG D+R++HW+    + L    +Q          A   + P     ++    ++IA
Sbjct: 106 EVLSGGMDSRLVHWDFSKPKCLNQFNMQELHSTTSDASAYMINPPFIHHLAKNSDGSIIA 285

Query: 132 SAASDSTVRIWSKKGSEVKYLQ 153
            A  +  + +++   S  K+LQ
Sbjct: 286 CALENGLIAVFN---STAKHLQ 342
>01598
          Length = 1545

 Score = 30.8 bits (68), Expect = 2.6,   Method: Compositional matrix adjust.
 Identities = 25/93 (26%), Positives = 46/93 (49%), Gaps = 1/93 (1%)
 Frame = +1

Query: 668 HSRIIWS-CDWSPDNKYFFTGSRDKKVVVWGECKSSHNPMEHPIRPCSSILDVGSSVTAV 726
           H R +++ C   PD+K   T ++D++VV+W             +   +S+  +G  V  V
Sbjct: 373 HMRPVFNICASGPDSKTLCTFAQDRQVVLWD---------LETMEAVASMATLGGHVYCV 525

Query: 727 SVCPVLNPAQRYIVAIGLESGKICIYSWNKTNQ 759
              P+ +P +   VA+G+  G   I +WN +N+
Sbjct: 526 RTSPI-DPGR---VAVGV--GDSMIRTWNMSNK 606
>34005
          Length = 456

 Score = 30.4 bits (67), Expect = 3.4,   Method: Compositional matrix adjust.
 Identities = 21/79 (26%), Positives = 35/79 (44%)
 Frame = +1

Query: 677 WSPDNKYFFTGSRDKKVVVWGECKSSHNPMEHPIRPCSSILDVGSSVTAVSVCPVLNPAQ 736
           WSPD  +  +GS D  V +W       + +   + P  ++    ++V AV+ CP     Q
Sbjct: 136 WSPDATFLASGSNDNSVNIW------DSTLGMDVPPLHTLTSHQAAVKAVAWCPW----Q 285

Query: 737 RYIVAIGLESGKICIYSWN 755
             ++A G  +    I  WN
Sbjct: 286 TRMLATGGGTNDRHIRFWN 342
>23308
          Length = 1107

 Score = 30.0 bits (66), Expect = 3.9,   Method: Compositional matrix adjust.
 Identities = 29/114 (25%), Positives = 49/114 (42%), Gaps = 3/114 (2%)
 Frame = -3

Query: 418 KKKDQKDRSQVT---WHEIARPQIHGYNIKCLAMIDRFQFVSGADEKVLRVFSAPRNFVE 474
           + +  K RSQV    WH  AR  I   +     ++  F+      + ++ + ++P    E
Sbjct: 949 RPQGSKGRSQVQGQQWHSKARTLISSLDQVFSEILTAFEVCPEIQQALVLIGASPLTPKE 770

Query: 475 NFSVISRQSLSHMLCDDQDLPEGATVPALGLSNKALFQGDIASQPFEEDELISP 528
            +++     L H+       PE   VP L  S +ALF+  +A Q    D  +SP
Sbjct: 769 CYNI----RLPHIC------PEADNVP-LKSSKQALFRHLVAEQVLSSDAALSP 641
>04358
          Length = 2430

 Score = 29.6 bits (65), Expect = 5.0,   Method: Compositional matrix adjust.
 Identities = 18/58 (31%), Positives = 27/58 (46%)
 Frame = +1

Query: 48   KVVITNLNGHTARVNCLQWIRTEDGSPSNELVSGGSDNRVIHWELENNQVLKSVRLQG 105
            KVV +   GHT  V CL W +      +  LV+GG D+ +  W  + + +      QG
Sbjct: 2116 KVVRSLSGGHTDTVRCLHWDK-----QTQTLVTGGEDSMLCLWSSDASGIQSPAPKQG 2274

 Score = 29.6 bits (65), Expect = 5.1,   Method: Compositional matrix adjust.
 Identities = 43/188 (22%), Positives = 79/188 (42%), Gaps = 4/188 (2%)
 Frame = +1

Query: 75   SNELVSGGSDNRVIHWELENNQVLKSVRLQGHEGPVCAVHAIYQSGPSEGEQHALIASAA 134
            ++ LV+  S N ++       ++ ++  L GH+  + ++  ++ + P       LI +A+
Sbjct: 1327 ADSLVAAASSNFMVRL-YSRCRLAQTNTLTGHDDVISSIRFLH-TDP------GLIMTAS 1482

Query: 135  SDSTVRIWSKKGSEVKYLQTLSFRDGFVLSVCLAILPGTNVPVLACG----DDDCRIHLY 190
             D TVRIW  + S  K +Q  S       SV L+     +  VL  G    +DD  +  +
Sbjct: 1483 HDHTVRIWDPRASVSKEVQRFSGEQNTKCSV-LSCDVNISDRVLCAGTEMSNDDAYLLFW 1659

Query: 191  IQQDDQFQKALSLCGHEDWIRGVEWATFGRDLFLASCSQDCLIRIWRLYMKPASFETKDG 250
             ++ D+         H+D I  V +        L   S D L+ ++ +        T+D 
Sbjct: 1660 DRRKDKLLGCYEDSHHDD-ITQVHFGPTSEKTLLTG-STDGLVNVFDVMQT-----TEDD 1818

Query: 251  SLRLKENT 258
            +L    NT
Sbjct: 1819 ALMSTYNT 1842
>15780
          Length = 735

 Score = 29.3 bits (64), Expect = 6.1,   Method: Composition-based stats.
 Identities = 19/58 (32%), Positives = 29/58 (50%)
 Frame = -1

Query: 35  GTSCSVVLYDPQKKVVITNLNGHTARVNCLQWIRTEDGSPSNELVSGGSDNRVIHWEL 92
           G   +V+++D      + +L  HT  V  L + R  DG+    L SGG DN +  W+L
Sbjct: 717 GADHTVIVWDIASGTAVAHLTAHTDTVYALCFSR--DGTV---LASGGMDNSIRLWDL 559
>16105
          Length = 960

 Score = 29.3 bits (64), Expect = 6.1,   Method: Compositional matrix adjust.
 Identities = 18/60 (30%), Positives = 28/60 (46%)
 Frame = -2

Query: 42  LYDPQKKVVITNLNGHTARVNCLQWIRTEDGSPSNELVSGGSDNRVIHWELENNQVLKSV 101
           L DP     + +L GH  R   + W      S  N LVS G+DN+++ W +   + +  V
Sbjct: 458 LTDP-----VVDLVGHQKRCCLIVW----HPSAQNVLVSAGADNKILFWNVGTGEPMLEV 306
>17602
          Length = 481

 Score = 29.3 bits (64), Expect = 6.7,   Method: Compositional matrix adjust.
 Identities = 22/83 (26%), Positives = 38/83 (45%), Gaps = 1/83 (1%)
 Frame = +3

Query: 560 IQKLYGHGYEIVCVACNNSKTLLASACKASQKEHAAIILWSTASWKQVQSLAFH-TLTVT 618
           ++ L  H   +  V  N   +L+ S+            +W TAS + + +L       V+
Sbjct: 33  LKTLPAHSDPVTAVHFNRDGSLIVSS-----SYDGLCRIWDTASGQCLXTLIDDDNPPVS 197

Query: 619 QMTFSPDDKFLLAVSRDRTWSLW 641
            + FSP+ K++LA + D T  LW
Sbjct: 198 FVKFSPNGKYILAATLDNTLKLW 266
>30295
          Length = 593

 Score = 28.9 bits (63), Expect = 9.3,   Method: Composition-based stats.
 Identities = 35/136 (25%), Positives = 54/136 (39%), Gaps = 2/136 (1%)
 Frame = +2

Query: 54  LNGHTARVNCLQWIRTEDGSPSNELVSGGSDNRVIHWELENNQVLKSVRLQGHEGPVCAV 113
           L  H A++  + W      + S  LVS   D ++I W+      + ++ L+      CA 
Sbjct: 233 LRXHLAKIYAMHW-----ATDSRNLVSASQDGKLIVWDGYTTNKVHAIPLRSSWVMTCAY 397

Query: 114 HAIYQSGPSEGEQHALIASAASDSTVRIWSKKGSE--VKYLQTLSFRDGFVLSVCLAILP 171
                  PS G     +A    D+   I+S K  E  V+  + L    G+ LS C  I  
Sbjct: 398 ------APSGG----YVACGGLDNICSIYSLKTREGNVRVSRELPGHTGY-LSCCRFI-- 538

Query: 172 GTNVPVLACGDDDCRI 187
             N  V + GD  C +
Sbjct: 539 DDNQIVTSSGDMTCAL 586
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|13878227|ref|NP_113569.1| WD repeat domain 6 [Mus
musculus]
         (1125 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

30256                                                                  48   2e-05
16105                                                                  39   0.013
11493                                                                  39   0.014
13335                                                                  37   0.040
12806                                                                  36   0.070
04358                                                                  36   0.081
19498                                                                  35   0.15 
04140                                                                  35   0.20 
03387                                                                  34   0.28 
05393                                                                  33   0.46 
14500                                                                  33   0.95 
15972                                                                  32   1.0  
04524                                                                  32   1.7  
23371                                                                  31   2.8  
27465                                                                  31   3.6  
19863                                                                  30   4.2  
31186                                                                  30   4.6  
01075                                                                  30   5.4  
02147                                                                  30   6.1  
12574                                                                  30   7.0  
>30256
          Length = 961

 Score = 48.1 bits (113), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 39/155 (25%), Positives = 64/155 (41%), Gaps = 2/155 (1%)
 Frame = +3

Query: 175 IVAGAVSNELLIWYPATALTDNKPVAPDRRVSGHVGVIFSMSYLESKGLLATASEDRSVR 234
           +V+GA    + +W P TA       +    + GH   ++S+ +      + + S D S+R
Sbjct: 321 VVSGAXDYTVRVWDPDTA-------SCLHTLQGHTNRVYSLQF--DGVYVVSGSLDTSIR 473

Query: 235 LWKVGDLRVPGGRVQNIGHCF-GHSARVWQVKLLENYLISAGEDCVCLVWS-HEGEILQA 292
           +W V        R   + H   GH +    ++L +N L+S   D    VW  H G+ LQ 
Sbjct: 474 VWDV--------RCGKLVHTLMGHQSLTSGLELKDNLLVSGNADSTVKVWDVHTGKCLQT 629

Query: 293 FXXXXXXXXXXXXTHERQAWVVTGGDDSGIRLWHL 327
                            + +VVT  DD  ++LW L
Sbjct: 630 LLGPNKHRSAVTCLQFNKKFVVTCSDDGTVKLWDL 734

 Score = 29.6 bits (65), Expect = 7.9,   Method: Compositional matrix adjust.
 Identities = 30/128 (23%), Positives = 50/128 (39%), Gaps = 5/128 (3%)
 Frame = +3

Query: 203 RRVSGHVGVIFSMSYLESKGLLATASEDRSVRLWKVGDLRVPGGRVQNIGHC----FGHS 258
           + + GH G ++S     +   + + S DRS+++W             + G C    +GHS
Sbjct: 24  KNLIGHTGGVWSSQM--TGNTVISGSTDRSLKVWNA-----------DTGVCTHTLYGHS 164

Query: 259 ARVWQVKLLENYLISAGEDCVCLVWSHE-GEILQAFXXXXXXXXXXXXTHERQAWVVTGG 317
           + V  + L    ++S   D    VW  E G  L                 +R   VV+G 
Sbjct: 165 STVRCLSLSGKKVVSGSRDATLRVWDIESGHCLNVLLGHMAAVRCVQYDGKR---VVSGA 335

Query: 318 DDSGIRLW 325
            D  +R+W
Sbjct: 336 XDYTVRVW 359
>16105
          Length = 960

 Score = 38.9 bits (89), Expect = 0.013,   Method: Compositional matrix adjust.
 Identities = 24/85 (28%), Positives = 43/85 (50%), Gaps = 5/85 (5%)
 Frame = -2

Query: 205 VSGHVGVIFSMSYL-ESKGLLATASEDRSVRLWKVGDLRVPGGRVQNIGHCFGHSAR--- 260
           V+GH G +  + +   +  ++A+AS+D +V++W++ D  +       +    GH  R   
Sbjct: 587 VAGHKGAVLDIQWCPHNDNVIASASDDCTVKVWQIPDSGLVTNLTDPVVDLVGHQKRCCL 408

Query: 261 -VWQVKLLENYLISAGEDCVCLVWS 284
            VW     +N L+SAG D   L W+
Sbjct: 407 IVWHPS-AQNVLVSAGADNKILFWN 336

 Score = 29.6 bits (65), Expect = 6.3,   Method: Compositional matrix adjust.
 Identities = 21/87 (24%), Positives = 38/87 (43%)
 Frame = -2

Query: 996  PEGHHLVASGSEDGSLHVFTLAVKMPEPEEADGEAELVPQLCVLEEYSVPCAHAAHVTGV 1055
            P   +++AS S+D ++ V+ +      P+         P + ++      C    H +  
Sbjct: 545  PHNDNVIASASDDCTVKVWQI------PDSGLVTNLTDPVVDLVGHQKRCCLIVWHPSAQ 384

Query: 1056 KILSPKLMVSASIDQRLTFWRLGQGEP 1082
             +L     VSA  D ++ FW +G GEP
Sbjct: 383  NVL-----VSAGADNKILFWNVGTGEP 318
>11493
          Length = 535

 Score = 38.5 bits (88), Expect = 0.014,   Method: Compositional matrix adjust.
 Identities = 22/105 (20%), Positives = 48/105 (45%), Gaps = 3/105 (2%)
 Frame = -2

Query: 581 YLYSTGRDSSYFQLFVHGGHLQPVLRQKACRGMNWVAGLRMVPDGSMVILGFHANEFVVW 640
           Y+Y+ G+           G+  PV +    +  N++  ++++PDG  +I+G  A+   +W
Sbjct: 435 YVYTGGKGCVKVWDISQPGNKNPVSQLDCLQRDNYIRSVKLLPDGRTLIVGGEASNLSIW 256

Query: 641 ---SPRSHEKLHIVNCGGGHRSWAFSDTEAAMAFTYLKDGEVMLY 682
              SP    K  + +      + A S  ++ + F+   DG + ++
Sbjct: 255 DLASPTPRIKAELTSAAPACYALAIS-PDSKVCFSCCSDGNIAVW 124
>13335
          Length = 863

 Score = 37.0 bits (84), Expect = 0.040,   Method: Compositional matrix adjust.
 Identities = 30/126 (23%), Positives = 51/126 (40%), Gaps = 1/126 (0%)
 Frame = +1

Query: 159 TLSSACLVGDTWKELTIVAGAVSNELLIWYPATALTDNKPVAPDRRV-SGHVGVIFSMSY 217
           T  +AC    +   L +  G   N + +W  +  +   +     R + SGH  ++ + ++
Sbjct: 355 TFGTACAENSSTCNLLLATGGKDNLIKLWTFSAQVGSPEVTLQCRDILSGHSDLVMACAF 534

Query: 218 LESKGLLATASEDRSVRLWKVGDLRVPGGRVQNIGHCFGHSARVWQVKLLENYLISAGED 277
             S  LLA+ S D+SVRLW      V G  + +I  C           +    L S   D
Sbjct: 535 SPSSALLASGSFDKSVRLWD----SVKGVALFSIEACHSRFVTCCAFSIDGTLLASGSMD 702

Query: 278 CVCLVW 283
            +  +W
Sbjct: 703 RIIKIW 720
>12806
          Length = 961

 Score = 36.2 bits (82), Expect = 0.070,   Method: Composition-based stats.
 Identities = 22/110 (20%), Positives = 51/110 (46%), Gaps = 3/110 (2%)
 Frame = +3

Query: 223 LLATASEDRSVRLWKVGDLRVPGGRVQNIGHCFGHSARVWQVKLLENYLISAGEDCVCLV 282
           ++ +AS D+++++W    + +    V       GH A++  + +  NYL+S  +D + + 
Sbjct: 468 IVVSASNDKTIKVWDNHTMTLKNTFV-------GHKAQITALDMSTNYLVSGSKDGIAMT 626

Query: 283 WS-HEGEILQAF--XXXXXXXXXXXXTHERQAWVVTGGDDSGIRLWHLAG 329
           W+  EG  +                  ++++ W+  G  + GI++W  +G
Sbjct: 627 WNVAEGSFVGKIDCDDQINAIKFNIENNKKKVWLFIGTQN-GIQIWDYSG 773
>04358
          Length = 2430

 Score = 36.2 bits (82), Expect = 0.081,   Method: Compositional matrix adjust.
 Identities = 23/64 (35%), Positives = 35/64 (54%), Gaps = 1/64 (1%)
 Frame = +1

Query: 174  TIVAGAVSNELLIWYPATALTDNKPVAPDRRVSGHVGVIFSMSYLESK-GLLATASEDRS 232
            ++VA A SN ++  Y    L      A    ++GH  VI S+ +L +  GL+ TAS D +
Sbjct: 1333 SLVAAASSNFMVRLYSRCRL------AQTNTLTGHDDVISSIRFLHTDPGLIMTASHDHT 1494

Query: 233  VRLW 236
            VR+W
Sbjct: 1495 VRIW 1506
>19498
          Length = 903

 Score = 35.0 bits (79), Expect = 0.15,   Method: Compositional matrix adjust.
 Identities = 19/72 (26%), Positives = 42/72 (58%)
 Frame = -1

Query: 171 KELTIVAGAVSNELLIWYPATALTDNKPVAPDRRVSGHVGVIFSMSYLESKGLLATASED 230
           ++L + + +V N +++W    AL  ++ VA  R   GH G++  +++      LA+ S+D
Sbjct: 576 QDLWLASCSVDNTIVVW---NALKFSEQVAVIR---GHAGMVKGVTWDPVGRYLASQSDD 415

Query: 231 RSVRLWKVGDLR 242
           +++R+W+  D +
Sbjct: 414 KTLRVWRTSDWK 379
>04140
          Length = 1869

 Score = 34.7 bits (78), Expect = 0.20,   Method: Compositional matrix adjust.
 Identities = 29/99 (29%), Positives = 46/99 (46%), Gaps = 3/99 (3%)
 Frame = +1

Query: 195 DNKPVAPDRRVSGHVG--VIFSMSYLESKGL-LATASEDRSVRLWKVGDLRVPGGRVQNI 251
           D+ P AP+R+++  +   ++      E K   +   +ED   RL +  DL +P     N+
Sbjct: 802 DDIPEAPERKMTDAINEPILLCRFPAEIKSFYMPRCAEDN--RLTESVDLLMP-----NV 960

Query: 252 GHCFGHSARVWQVKLLENYLISAGEDCVCLVWSHEGEIL 290
           G   G S R+W  K LE+ L + G     L+  H  E L
Sbjct: 961 GEIVGGSMRIWDEKQLEDGLQARGHRPQALLLVHRPETL 1077
>03387
          Length = 1891

 Score = 34.3 bits (77), Expect = 0.28,   Method: Compositional matrix adjust.
 Identities = 31/110 (28%), Positives = 49/110 (44%), Gaps = 5/110 (4%)
 Frame = +1

Query: 179 AVSNELLIWYPATALTDNKPVAPDRRVSGHVGVIFSMSYLE-SKGLLATASEDRSVRLWK 237
           A   +L+IW   +    N    P   V  H   +  +S+   S+ +LAT S D++V LW 
Sbjct: 571 ADDQKLMIWDTRS----NTTSKPSHVVDAHTAEVNCLSFNPYSEFILATGSADKTVALWD 738

Query: 238 VGDLRVPGGRVQNIGHCF-GHSARVWQVKLL---ENYLISAGEDCVCLVW 283
           + +L++         H F  H   ++QV+     E  L S+G D    VW
Sbjct: 739 LRNLKLK-------LHSFESHKDEIFQVQWSPHNETILASSGTDRRLHVW 867
>05393
          Length = 904

 Score = 33.5 bits (75), Expect = 0.46,   Method: Compositional matrix adjust.
 Identities = 19/61 (31%), Positives = 33/61 (54%), Gaps = 2/61 (3%)
 Frame = +1

Query: 1047 AHAAHVTGVKILS--PKLMVSASIDQRLTFWRLGQGEPTFMNSTVYHVPDVADMDCWPVS 1104
            AH++ VTGV + S  P LM++ S D+ +  W +   +PT + S    + ++    C P +
Sbjct: 214  AHSSCVTGVCLSSQIPGLMITTSEDKTMKVWDIQDDKPTHVFSRNLKMKELHCTGCCPEA 393

Query: 1105 P 1105
            P
Sbjct: 394  P 396
>14500
          Length = 1238

 Score = 32.7 bits (73), Expect = 0.95,   Method: Compositional matrix adjust.
 Identities = 22/84 (26%), Positives = 39/84 (46%), Gaps = 5/84 (5%)
 Frame = +3

Query: 171 KELTIVAGAVSNELLIW-YPATALTDNKPVAPDRRVSGHVGVIFSMSYLESKGLLATASE 229
           +EL    G   N+L+IW YPA        ++    ++GH   +  M+       + +A+ 
Sbjct: 372 RELISSHGFAQNQLIIWKYPA--------MSRVAELTGHTARVLHMAMSPDGETVVSAAA 527

Query: 230 DRSVRLWKV----GDLRVPGGRVQ 249
           D ++RLWK      + + P  +VQ
Sbjct: 528 DETLRLWKCFTVDKEKKRPKQKVQ 599
>15972
          Length = 1069

 Score = 32.3 bits (72), Expect = 1.0,   Method: Compositional matrix adjust.
 Identities = 16/43 (37%), Positives = 25/43 (58%)
 Frame = +3

Query: 201 PDRRVSGHVGVIFSMSYLESKGLLATASEDRSVRLWKVGDLRV 243
           P+R  SGH G +  ++   S  L  T S+DR++RLW   + R+
Sbjct: 213 PERTFSGHKGPVRHLAVHPSGKLTLTVSQDRTLRLWNNMNGRI 341
>04524
          Length = 1340

 Score = 31.6 bits (70), Expect = 1.7,   Method: Compositional matrix adjust.
 Identities = 22/87 (25%), Positives = 39/87 (44%), Gaps = 3/87 (3%)
 Frame = -1

Query: 207  GHVGVIFSMSYLESKGLLATASEDRSVRLWKVGDLRVPGGRVQNI-GHCFGHSARVWQVK 265
            GH+ ++  +     +G + T   D  +R+ +  +         NI  +C GH+  V  + 
Sbjct: 1034 GHLSMVLDVCLTGREGHVVTCDRDEKIRVSQFPN-------AYNIHTYCLGHTQFVNCLV 876

Query: 266  LLENY--LISAGEDCVCLVWSHEGEIL 290
             +E +  LIS   DC    W+ EG+ L
Sbjct: 875  YVEEFRVLISGSGDCTVRAWNMEGKQL 795
>23371
          Length = 762

 Score = 30.8 bits (68), Expect = 2.8,   Method: Composition-based stats.
 Identities = 13/45 (28%), Positives = 27/45 (60%), Gaps = 2/45 (4%)
 Frame = -2

Query: 906 LLAESFHHKRCVLKVH--SFTHEAPNQRRRLILCSAATDGSLAFW 948
           L+ + FHH+  + + +  SF    PN++   I C +++DG+L ++
Sbjct: 347 LVPDCFHHEHSLFRPNFPSFKFVCPNEQNIRIACFSSSDGALIYY 213
>27465
          Length = 658

 Score = 30.8 bits (68), Expect = 3.6,   Method: Composition-based stats.
 Identities = 14/32 (43%), Positives = 18/32 (56%)
 Frame = -1

Query: 207 GHVGVIFSMSYLESKGLLATASEDRSVRLWKV 238
           GH   I  +S+  S  L+AT S D + RLW V
Sbjct: 112 GHTAEIVCVSFNPSSTLIATGSMDTTCRLWDV 17
>19863
          Length = 502

 Score = 30.4 bits (67), Expect = 4.2,   Method: Composition-based stats.
 Identities = 15/66 (22%), Positives = 32/66 (48%)
 Frame = +1

Query: 173 LTIVAGAVSNELLIWYPATALTDNKPVAPDRRVSGHVGVIFSMSYLESKGLLATASEDRS 232
           L +V+G+    +++W       D +      R+ GH G +  + + + +  L + S D +
Sbjct: 10  LQLVSGSSDMSIVVW-------DVENGVQKLRLQGHAGWVNDVHFSQDQCWLLSCSNDNT 168

Query: 233 VRLWKV 238
           VR+W +
Sbjct: 169 VRIWNI 186
>31186
          Length = 690

 Score = 30.4 bits (67), Expect = 4.6,   Method: Composition-based stats.
 Identities = 13/50 (26%), Positives = 23/50 (46%)
 Frame = +1

Query: 825 PSRLACHVMHLSSHRLDEYWDRQRNKHKMIKVDPETRYMSLAICELDNDR 874
           P  + CH    + HR++  W++ R K+ +  +      M + IC    DR
Sbjct: 262 PCLVPCHHYVSTFHRMNRLWNKARPKYNLTIITLPCSKMEMFICIYSPDR 411
>01075
          Length = 1212

 Score = 30.0 bits (66), Expect = 5.4,   Method: Composition-based stats.
 Identities = 26/92 (28%), Positives = 41/92 (44%), Gaps = 3/92 (3%)
 Frame = +2

Query: 195 DNKPVAPDRRVSGHVG--VIFSMSYLESKGL-LATASEDRSVRLWKVGDLRVPGGRVQNI 251
           D+ P AP+R+++  +   ++      E K   +   +ED   RL +  DL +P     N+
Sbjct: 152 DDIPEAPERKMTDAINEPILLCRFPAEIKSFYMPRCAEDN--RLTESVDLLMP-----NV 310

Query: 252 GHCFGHSARVWQVKLLENYLISAGEDCVCLVW 283
           G   G S R+W  K LE+     G D     W
Sbjct: 311 GEIVGGSMRIWDEKQLEDGFKREGIDPKPYYW 406
>02147
          Length = 1547

 Score = 30.0 bits (66), Expect = 6.1,   Method: Composition-based stats.
 Identities = 18/58 (31%), Positives = 29/58 (50%)
 Frame = +2

Query: 181 SNELLIWYPATALTDNKPVAPDRRVSGHVGVIFSMSYLESKGLLATASEDRSVRLWKV 238
           SNE L+       TD +P    +  +GH   I    +L     + +AS+D++VRLW +
Sbjct: 353 SNEKLLKVFDLVNTDAEP----KSFAGHTSNIKGALFLSDGKRIISASDDKTVRLWSL 514
>12574
          Length = 521

 Score = 29.6 bits (65), Expect = 7.0,   Method: Composition-based stats.
 Identities = 24/104 (23%), Positives = 44/104 (42%), Gaps = 9/104 (8%)
 Frame = +3

Query: 189 PATALTDNKPVAPDR-------RVSGHVGVIFSMSYLESKGLLATASEDRSVRLWKVGDL 241
           PA+A +  K  A  +        ++GH   + ++ +  +   LA++S D+ +++W   D 
Sbjct: 105 PASATSGTKSSATQKPTYTLKFTLAGHTKALSAVKFSPNGDWLASSSADKLIKIWGAYD- 281

Query: 242 RVPGGRVQNI--GHCFGHSARVWQVKLLENYLISAGEDCVCLVW 283
               G+ +    GH  G S   W        L SA +D    +W
Sbjct: 282 ----GKFEKTIAGHKLGLSDVAWSSD--SKLLCSASDDKTLKIW 395
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|21313210|ref|NP_080144.1| thioredoxin-related
transmembrane protein 2 [Mus musculus]
         (295 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

06936                                                                  46   2e-05
18455                                                                  37   0.013
11167                                                                  34   0.074
03582                                                                  32   0.28 
35861                                                                  32   0.32 
04510                                                                  30   1.2  
28335                                                                  30   1.2  
07729                                                                  29   2.6  
05060                                                                  28   3.9  
00809                                                                  28   4.7  
03206                                                                  28   5.9  
03396                                                                  27   7.7  
>06936
          Length = 2198

 Score = 45.8 bits (107), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 29/77 (37%), Positives = 39/77 (50%), Gaps = 2/77 (2%)
 Frame = +3

Query: 153 DKRVTWIVEFFANWSNDCQSFAPIY--ADLSLKYNCSGLNFGKVDVGRYTDVSTRYKVST 210
           +K    +VEFFA W   C+  AP Y  A  +L  N   +   KVD    TDV ++Y VS 
Sbjct: 189 EKHSLMLVEFFAPWCGHCKKLAPQYELAATALLKNDPPVPLAKVDCTEETDVCSKYGVSG 368

Query: 211 SPLTRQLPTLILFQGGK 227
                  PTL +F+GG+
Sbjct: 369 ------YPTLKVFRGGE 401

 Score = 35.0 bits (79), Expect = 0.036,   Method: Compositional matrix adjust.
 Identities = 29/94 (30%), Positives = 41/94 (43%), Gaps = 12/94 (12%)
 Frame = +3

Query: 148  EELERDKRVTWIVEFFANWSNDCQSFAPIYADLSLKY-NCSGLNFGKVDVGRYTDVSTRY 206
            EEL  D     ++EF+A W   C++ AP Y +L+ K  N   +   K+D     DV   Y
Sbjct: 1218 EELVNDPEKDVLIEFYAPWCGHCKTLAPKYDELAEKLKNEPEIVIAKMD-ATANDVPPPY 1394

Query: 207  KVSTSPLTRQLPTLIL-----------FQGGKEV 229
             V      R  PTL             ++GG+EV
Sbjct: 1395 DV------RGFPTLYFAPKGSKSSPKKYEGGREV 1478
>18455
          Length = 499

 Score = 36.6 bits (83), Expect = 0.013,   Method: Compositional matrix adjust.
 Identities = 20/71 (28%), Positives = 35/71 (49%), Gaps = 1/71 (1%)
 Frame = +2

Query: 160 VEFFANWSNDCQSFAPIYADLSLKY-NCSGLNFGKVDVGRYTDVSTRYKVSTSPLTRQLP 218
           V+FFA W + CQ  API+ +L+            K+D  +Y  +   ++V      +  P
Sbjct: 203 VKFFAPWCSHCQRLAPIWEELAKALIKEPSATISKIDCTQYRSICQDFEV------KGYP 364

Query: 219 TLILFQGGKEV 229
           TL+  + GK++
Sbjct: 365 TLLWIEDGKKI 397
>11167
          Length = 485

 Score = 33.9 bits (76), Expect = 0.074,   Method: Compositional matrix adjust.
 Identities = 18/73 (24%), Positives = 32/73 (43%)
 Frame = -3

Query: 159 IVEFFANWSNDCQSFAPIYADLSLKYNCSGLNFGKVDVGRYTDVSTRYKVSTSPLTRQLP 218
           +V F+ +W+  C     +  +L+   +   + F +V      DVS RY +        +P
Sbjct: 477 VVHFWTDWAPQCAQMDDVMKELASDMHYVNVVFVRVAAEDLADVSQRYNIVA------VP 316

Query: 219 TLILFQGGKEVIR 231
           T I  +G  +V R
Sbjct: 315 TFIFLKGKDQVDR 277
>03582
          Length = 1967

 Score = 32.0 bits (71), Expect = 0.28,   Method: Compositional matrix adjust.
 Identities = 14/36 (38%), Positives = 21/36 (58%)
 Frame = +3

Query: 149  ELERDKRVTWIVEFFANWSNDCQSFAPIYADLSLKY 184
            E+  DK     VEF+A W   C+  API+ +L+ K+
Sbjct: 1161 EVALDKTKGVFVEFYAPWCGHCKQLAPIWDELADKF 1268

 Score = 31.2 bits (69), Expect = 0.53,   Method: Compositional matrix adjust.
 Identities = 22/64 (34%), Positives = 29/64 (45%), Gaps = 2/64 (3%)
 Frame = +2

Query: 159 IVEFFANWSNDCQSFAPIYADL--SLKYNCSGLNFGKVDVGRYTDVSTRYKVSTSPLTRQ 216
           +VEF+A W   C++ AP YA    +LK   S +   KVD    T +     V      R 
Sbjct: 176 LVEFYAPWCGHCKALAPEYAKAAQTLKDENSDVKLAKVDATIETSLGENMGV------RG 337

Query: 217 LPTL 220
            PTL
Sbjct: 338 YPTL 349
>35861
          Length = 850

 Score = 32.0 bits (71), Expect = 0.32,   Method: Compositional matrix adjust.
 Identities = 14/40 (35%), Positives = 21/40 (52%)
 Frame = +3

Query: 148 EELERDKRVTWIVEFFANWSNDCQSFAPIYADLSLKYNCS 187
           +E+  DK     VEF+A W   C+   PI+ +L  K+  S
Sbjct: 603 KEVALDKSKDVFVEFYAPWCGHCKQLVPIWDELGEKFQDS 722
>04510
          Length = 685

 Score = 30.0 bits (66), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 13/34 (38%), Positives = 17/34 (50%)
 Frame = +2

Query: 144 KTIDEELERDKRVTWIVEFFANWSNDCQSFAPIY 177
           K  D +   +K    +VEFFA W   C+  AP Y
Sbjct: 368 KKSDFQSTIEKHSLMLVEFFAPWCGHCKKLAPQY 469
>28335
          Length = 601

 Score = 30.0 bits (66), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 17/55 (30%), Positives = 26/55 (47%), Gaps = 1/55 (1%)
 Frame = -2

Query: 159 IVEFFANWSNDCQSFAPIYADL-SLKYNCSGLNFGKVDVGRYTDVSTRYKVSTSP 212
           ++EF+A W   CQ   P Y +L +L  +   +   K+D     D  T Y+V   P
Sbjct: 486 LIEFYAPWCGHCQQLEPKYNELATLLKDEPDIVXAKIDATA-NDTPTPYEVKGFP 325
>07729
          Length = 1131

 Score = 28.9 bits (63), Expect = 2.6,   Method: Compositional matrix adjust.
 Identities = 15/58 (25%), Positives = 30/58 (51%)
 Frame = -2

Query: 188  GLNFGKVDVGRYTDVSTRYKVSTSPLTRQLPTLILFQGGKEVIRRPQIDKKGRAVSWT 245
            G+ +G V VG+YTD+ T++      +   + TLI F+   +  R+     + +  S++
Sbjct: 1025 GMGWGDVGVGKYTDILTKFT*HL-EIDLYIDTLITFKPSTDAARKHHTHAEEKYSSYS 855
>05060
          Length = 2391

 Score = 28.1 bits (61), Expect = 3.9,   Method: Compositional matrix adjust.
 Identities = 14/53 (26%), Positives = 27/53 (50%), Gaps = 10/53 (18%)
 Frame = -2

Query: 131 LYMGPEYIKYFNDKTIDEELERDKRVTWIVEFFANWS----------NDCQSF 173
           L++ P   KY ++K +  ++    R+T  V+F+ NWS          +DC ++
Sbjct: 545 LFIQPHSSKYSSEKWVSXKITPFXRITRCVKFYINWSIKITEHCSG*SDCHAY 387
>00809
          Length = 2098

 Score = 28.1 bits (61), Expect = 4.7,   Method: Compositional matrix adjust.
 Identities = 17/62 (27%), Positives = 32/62 (51%), Gaps = 4/62 (6%)
 Frame = +3

Query: 88  QHVGNIFMFSK----VANAILFFRLDIRMGLLYLTLCIVFLMTCKPPLYMGPEYIKYFND 143
           +HV  +F F+K       ++++  + IR   ++LTL   FL T    + +GP +  + N 
Sbjct: 735 KHVNALFRFAKNFLKRQKSVIY*NITIRFRAVFLTLFSNFLQTHTRGVSLGPHWGAHCNP 914

Query: 144 KT 145
           +T
Sbjct: 915 QT 920
>03206
          Length = 1682

 Score = 27.7 bits (60), Expect = 5.9,   Method: Compositional matrix adjust.
 Identities = 18/46 (39%), Positives = 26/46 (56%), Gaps = 6/46 (13%)
 Frame = +2

Query: 57  NPCDFDWREVEILMFLSAIVMMKNRRSI------TVEQHVGNIFMF 96
           NP +FDWR V  L+FL+  V   NR+ +        E+HV ++F F
Sbjct: 110 NPVNFDWR-VRGLVFLTYRVF--NRKPVMQNIA*IFEKHVSSVFKF 238
>03396
          Length = 714

 Score = 27.3 bits (59), Expect = 7.7,   Method: Compositional matrix adjust.
 Identities = 13/59 (22%), Positives = 28/59 (47%)
 Frame = -1

Query: 156 VTWIVEFFANWSNDCQSFAPIYADLSLKYNCSGLNFGKVDVGRYTDVSTRYKVSTSPLT 214
           V+ I +++  + +     +P+Y ++ LKY         V    Y ++  +Y+   SPL+
Sbjct: 696 VSCICQYYLKYQSSDNPLSPVYVNIYLKYQSXDSPLSPV----YVNIYLKYQSXDSPLS 532
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|66793429|ref|NP_056544.2| acyl-Coenzyme A oxidase 1
[Mus musculus]
         (661 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

04495                                                                  47   2e-05
14390                                                                  37   0.026
>04495
          Length = 1549

 Score = 47.0 bits (110), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 42/156 (26%), Positives = 65/156 (41%), Gaps = 4/156 (2%)
 Frame = +2

Query: 102 LHLGMFLPTLLHQATEEQQERFFMPAWNLEITGTYAQTEMGHGTHLRGLETTATYDPKTQ 161
           LH  + +P + H  T+EQ E+F     +    G  A +E G G+ L+G+ T A  D    
Sbjct: 296 LHSDIVMPYITHYGTKEQIEKFIPRMVDGTCIGAIAMSEPGAGSDLQGIRTNAKRD--GD 469

Query: 162 EFILNSPTVTSIKWWPGGLGKTSNHAIVLAQLITRGEC----YGLHAFVVPIREIGTHKP 217
           ++ILN   V     +  G        +VL   IT  E     +G+  F+V          
Sbjct: 470 DWILNGSKVFITNGYMSG--------VVLVVAITNMEAKSAAHGISLFLV-------EDG 604

Query: 218 LPGITVGDIGPKFGYEEMDNGYLKMDNYRIPRENML 253
           +PG   G    K G +  D   L  ++ R+P   +L
Sbjct: 605 MPGFKKGRKLNKVGLKAQDTSELFFEDVRLPNSALL 712
>14390
          Length = 1789

 Score = 37.0 bits (84), Expect = 0.026,   Method: Compositional matrix adjust.
 Identities = 32/155 (20%), Positives = 60/155 (38%), Gaps = 3/155 (1%)
 Frame = -3

Query: 107  FLPTLLHQATEEQQERFFMPAWNLEITGTYAQTEMGHGTHLRGLETTATYDPKTQEFILN 166
             + TLL     +QQ+  ++P    ++ G++  +E   G+    L T A            
Sbjct: 1703 LINTLLMNLGTQQQKDTYLPRLTKDMVGSFCLSEAESGSDAFSLRTQAVQQG-------G 1545

Query: 167  SPTVTSIKWWPGGLGKTSNHA---IVLAQLITRGECYGLHAFVVPIREIGTHKPLPGITV 223
               +T  K W      ++ HA   +V+A         G+  F+V        +   G+T+
Sbjct: 1544 DYVITGEKVWI----SSAEHAGVFLVMANAKPSDGYKGITCFIV-------DRDTEGLTI 1398

Query: 224  GDIGPKFGYEEMDNGYLKMDNYRIPRENMLMKYAQ 258
            G+   K G        +  D  R+P  N+L ++ +
Sbjct: 1397 GNKEDKLGLRSSSTCVVNFDGVRVPESNILGEFGK 1293
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|7305379|ref|NP_038774.1| pleckstrin homology domain
containing, family B (evectins) member 1 [Mus musculus]
         (243 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

14481                                                                  45   2e-05
05354                                                                  33   0.11 
13952                                                                  32   0.27 
>14481
          Length = 561

 Score = 45.4 bits (106), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 25/67 (37%), Positives = 37/67 (55%), Gaps = 3/67 (4%)
 Frame = -1

Query: 75  IKVGQECQDVQPPEGRSRDG---LLTVNLREGSRLHLCAETRDDAIAWKTALMEANSTPA 131
           IK G E +    P    R G   LL +++R+G+ L LCAE+ DD  AW+ +L EA ++  
Sbjct: 528 IKTGTEIKATTSPPDEVRGGVSCLLELDMRDGNHLLLCAESPDDMKAWQYSLEEARTSRI 349

Query: 132 PAGATVP 138
           P+    P
Sbjct: 348 PSAGPAP 328
>05354
          Length = 2173

 Score = 33.1 bits (74), Expect = 0.11,   Method: Compositional matrix adjust.
 Identities = 26/73 (35%), Positives = 33/73 (45%), Gaps = 6/73 (8%)
 Frame = +1

Query: 5   TPVPPDSILESPFEEMALVRGGWLWRQSSILRRWKRNWFALWLDGTLG------YYHDET 58
           +P+ P  I  SPF ++    G  LW +SSI    KR  F L  + TLG      +YH   
Sbjct: 679 SPISPCLI*LSPFCQLF---GKLLWMRSSISXIMKRIGFFLL*NPTLGLLMKMCHYHLNN 849

Query: 59  AQDEEDRVVIHFN 71
            Q E      HFN
Sbjct: 850 TQCEA---FTHFN 879
>13952
          Length = 577

 Score = 31.6 bits (70), Expect = 0.27,   Method: Compositional matrix adjust.
 Identities = 16/40 (40%), Positives = 20/40 (50%)
 Frame = -3

Query: 23  VRGGWLWRQSSILRRWKRNWFALWLDGTLGYYHDETAQDE 62
           V+ GWL +Q    + WKR WF   L+    YY   TA  E
Sbjct: 419 VKEGWLMKQGGRYKNWKRRWFI--LNDNCLYYFQYTADKE 306
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|21314830|ref|NP_647453.1| polyposis locus protein
1-like 1 [Mus musculus]
         (201 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

18785                                                                  44   3e-05
17358                                                                  28   3.2  
06375                                                                  27   3.8  
>18785
          Length = 1091

 Score = 44.3 bits (103), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 25/94 (26%), Positives = 46/94 (48%)
 Frame = -3

Query: 60  VIGFVYPAYASVKAIESPSKEDDTVWLTYWVVYALFGLVEFFSDLLLFWFPFYYAGKCAF 119
           + G + PA  + +A+   +KE+   W  YW+VY     VE   D    W PFY   K   
Sbjct: 939 IFGTLLPARNTHEAL--GNKEELLTWSKYWIVYGCLMTVEIVGDTFFTWLPFYGETKLLI 766

Query: 120 LLFCMTPGPWNGALLLYHRVIRPLFLKHHMALDS 153
           +L+ +   P + ++ ++  ++ PL  ++   LD+
Sbjct: 765 VLWLVISAP-SASVWIFDVILNPLMGRYMHRLDA 667
>17358
          Length = 635

 Score = 27.7 bits (60), Expect = 3.2,   Method: Compositional matrix adjust.
 Identities = 14/42 (33%), Positives = 18/42 (42%), Gaps = 10/42 (23%)
 Frame = +3

Query: 117 CAFLLFCMTPGPWN----------GALLLYHRVIRPLFLKHH 148
           C+ +L  MTPGPWN          G   L+    R L +K  
Sbjct: 507 CSCVLL*MTPGPWNRLTPQRAAVLGTECLWKDTRRALLMKSS 632
>06375
          Length = 787

 Score = 27.3 bits (59), Expect = 3.8,   Method: Compositional matrix adjust.
 Identities = 14/39 (35%), Positives = 21/39 (53%)
 Frame = +2

Query: 76  SPSKEDDTVWLTYWVVYALFGLVEFFSDLLLFWFPFYYA 114
           +PS  + T WLT+  +  L   V FF  LLLF + + + 
Sbjct: 125 TPSSSNGTJWLTFSCLVPLICAVXFFVMLLLFMYNYIFT 241
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|23956140|ref|NP_079914.1| glycerophosphodiester
phosphodiesterase domain containing 1 [Mus musculus]
         (314 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

17762                                                                  45   3e-05
33385                                                                  36   0.026
>17762
          Length = 1950

 Score = 45.4 bits (106), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 30/106 (28%), Positives = 45/106 (42%), Gaps = 13/106 (12%)
 Frame = +2

Query: 41  RHISHRGGAGENLENTMAAFQHAVTIGTDMLELDCHITKDEQVVVSHDANLKRSTGV--- 97
           R  +HRG  G   ENT  AFQ AV  G   LE D  ++ +   ++ HD+   R+T V   
Sbjct: 266 RLFAHRGAEGIAPENTEVAFQRAVQYGAFGLESDVRLSLEGIPIIXHDSTFLRTTNVKDV 445

Query: 98  ----------NVNVSDLKYCELPPYLCKLDVPFQRACKCEGKDTRI 133
                       N++++K      +   +D PF  A     +D  I
Sbjct: 446 FPNRSGDDVSRFNLTEIKSLNAGNWFFDID-PFSTAGSVSDRDRHI 580
>33385
          Length = 567

 Score = 35.8 bits (81), Expect = 0.026,   Method: Compositional matrix adjust.
 Identities = 19/49 (38%), Positives = 29/49 (59%)
 Frame = -1

Query: 42  HISHRGGAGENLENTMAAFQHAVTIGTDMLELDCHITKDEQVVVSHDAN 90
           H    GGAGE++ + ++A  H      DM+ELD H+T D   V+ HD++
Sbjct: 519 HCRGSGGAGESIASFLSAHAHHA----DMVELDVHLTADGIPVIYHDSD 385
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|27261824|ref|NP_705807.2| synaptic vesicle
glycoprotein 2 b [Mus musculus]
         (683 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

08272                                                                  47   3e-05
12029                                                                  39   0.006
27264                                                                  39   0.007
27746                                                                  38   0.012
17824                                                                  38   0.014
08005                                                                  33   0.45 
35278                                                                  28   8.6  
>08272
          Length = 1326

 Score = 46.6 bits (109), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 40/158 (25%), Positives = 68/158 (43%)
 Frame = +1

Query: 250 ASAMAWSIIPHYGWGFSMGTNYHFHSWRVFVIVCALPATVSMVALKFMPESPRFLLEMGK 309
           AS   W++    G G      +   +WR    +CA      ++     PES R+L   GK
Sbjct: 235 ASVPCWAV----GAGMLCLVAWQVPNWRYLHFICAAITAPMLLGWFVSPESVRWLAAKGK 402

Query: 310 HDEAWMILKQVHDTNMRAKGTPEKVFTVSHIKTPKQMDEFIEIQSSTGTWYQRWLVRFMT 369
              A  ++ ++   N R K             T +Q+   +E + S G   +++   + T
Sbjct: 403 VKAAEEVVDRIARMNGRRKAP----------NTCEQLCVLVEDERSRGNNNEKY--AYHT 546

Query: 370 IFKQVWDNALYCVMGPYRMNTLILAVVWFTMALSYYGL 407
           +FK  W NA         MNTL+L   W ++++S+YG+
Sbjct: 547 LFKG-WRNA---------MNTLVLGFAWMSLSMSFYGI 630

 Score = 36.2 bits (82), Expect = 0.047,   Method: Compositional matrix adjust.
 Identities = 31/113 (27%), Positives = 52/113 (46%), Gaps = 9/113 (7%)
 Frame = +1

Query: 538 IYLVSFLGSLSVLPGNIISALLMDRIGRLKMIGGSM--LISAVCCFFLFFGNSESAMIGW 595
           ++L  FL S+  +P  + ++LL+  +GR     GSM  L++++  F +   +  ++    
Sbjct: 661 VFLNMFLLSVVEVPLTLATSLLVIYVGRRWT--GSMFFLLASLTGFGILIADRTASDEAK 834

Query: 596 QCLFCGTSI-------AAWNALDVITVELYPTNQRATAFGILNGLCKFGAILG 641
             +    +I       AAW  +   TVELYPT  R    G  N   + G IL 
Sbjct: 835 GTIISAVAICSKLFIAAAWTCMQTFTVELYPTVIRTLGLGAANTAARVGGILA 993
>12029
          Length = 605

 Score = 39.3 bits (90), Expect = 0.006,   Method: Composition-based stats.
 Identities = 38/150 (25%), Positives = 57/150 (38%), Gaps = 4/150 (2%)
 Frame = +3

Query: 262 GWGFSMG----TNYHFHSWRVFVIVCALPATVSMVALKFMPESPRFLLEMGKHDEAWMIL 317
            W  +M       +    W    I+ +L     ++    +PES R+L   G+  EA  ++
Sbjct: 195 AWAIAMALYALVAWQLPDWSYLHIINSLIGVPFLLTWFVIPESARWLATKGRLQEAEAVI 374

Query: 318 KQVHDTNMRAKGTPEKVFTVSHIKTPKQMDEFIEIQSSTGTWYQRWLVRFMTIFKQVWDN 377
            +V   N RA   P    T   +K     DE    Q    T+   +  R +         
Sbjct: 375 ARVARVNRRA--VP--AHTAQTLKRVAD-DESKARQGRRYTYLDVYRGRRLA-------- 515

Query: 378 ALYCVMGPYRMNTLILAVVWFTMALSYYGL 407
                     M TLIL  +WFTM+ SYYG+
Sbjct: 516 ----------MTTLILNFIWFTMSFSYYGM 575
>27264
          Length = 436

 Score = 38.9 bits (89), Expect = 0.007,   Method: Composition-based stats.
 Identities = 21/71 (29%), Positives = 32/71 (45%)
 Frame = +1

Query: 579 CCFFLFFGNSESAMIGWQCLFCGTSIAAWNALDVITVELYPTNQRATAFGILNGLCKFGA 638
           C   ++   S    +    +F G   AA  ALD +  E++PT  RAT   I     + G 
Sbjct: 1   CSALMYLVRSSLQNLVVSAVFSGAISAANAALDCLITEVFPTKLRATGVAISMVAARLGG 180

Query: 639 ILGNTIFASFV 649
           I+GN + A  +
Sbjct: 181 IIGNIVIAQLL 213
>27746
          Length = 544

 Score = 38.1 bits (87), Expect = 0.012,   Method: Composition-based stats.
 Identities = 39/178 (21%), Positives = 69/178 (38%), Gaps = 9/178 (5%)
 Frame = +2

Query: 241 IFWMTGGIYASA-MAWSIIPHYGWGFSMGTNYHFHSWRVFVIVCALPATVSMVALKFMPE 299
           +F+  GG+ A A +AW +                  WR   I+   P  + +     +PE
Sbjct: 83  MFFFAGGLLALAGIAWFV----------------RDWRYLDIIVTSPVLLYLSYWCLIPE 214

Query: 300 SPRFLLEMGKHDEAWMILKQVHDTNMRAKGTPEKVFTVSHIKTPKQMDEFI-----EIQS 354
           SPR+L++  +  EA +I+ +    N   K TP     ++      Q D  +       + 
Sbjct: 215 SPRWLIQKQRFXEAQVIINKAAKVN---KVTPPPDLKLT------QQDSHVTGCRDNRKD 367

Query: 355 STGTWYQRWLVRFMTIFKQVWDNALYCVMGPYRM---NTLILAVVWFTMALSYYGLTV 409
           ++G    RW+V               C     +M    T ++   WF ++L YY L++
Sbjct: 368 NSGGGRGRWVV---------------CEFLSSKMLLGRTFVVCFNWFVVSLVYYALSL 496
>17824
          Length = 450

 Score = 37.7 bits (86), Expect = 0.014,   Method: Composition-based stats.
 Identities = 17/39 (43%), Positives = 25/39 (64%), Gaps = 1/39 (2%)
 Frame = -2

Query: 276 WRVFVIVCALPATVSMVALKFMPESPRFLL-EMGKHDEA 313
           W +     ALP+ + ++ + F PESPRFLL + GK +EA
Sbjct: 242 WPLLFAFNALPSIMCLILMPFCPESPRFLLIKQGKDEEA 126
>08005
          Length = 593

 Score = 32.7 bits (73), Expect = 0.45,   Method: Composition-based stats.
 Identities = 25/75 (33%), Positives = 38/75 (50%), Gaps = 3/75 (4%)
 Frame = +3

Query: 111 LFFVLGLALMADGVEIFVVSFALPSAEKDMCLSSSKKGMLGLIVYLGMMAG---AFILGG 167
           L  +LG   + D V I +V   LP   +D+  S S     G+++ L  +     A +LG 
Sbjct: 24  LIVILGTVTL-DAVGIGLVMPVLPGLLRDIVHSDSIASHYGVLLALYALMQFLCAPVLGA 200

Query: 168 LADKLGRKKVLSMSL 182
           L+D+ GR+ VL  SL
Sbjct: 201 LSDRFGRRPVLLASL 245
>35278
          Length = 693

 Score = 28.5 bits (62), Expect = 8.6,   Method: Compositional matrix adjust.
 Identities = 35/141 (24%), Positives = 54/141 (38%), Gaps = 13/141 (9%)
 Frame = +3

Query: 555 ISALLMDRIGRLKMIGGSMLISAVCCFF---LFFGNSES----------AMIGWQCLFCG 601
           +S ++M++ GR K +    L + +CC     +  G  ES          A++G   +   
Sbjct: 120 LSMVIMNKFGRKKPLLVCFLAAGICCIVSASIPRGTGESDYLKHVSTIFAIVGRFFM--- 290

Query: 602 TSIAAWNALDVITVELYPTNQRATAFGILNGLCKFGAILGNTIFASFVGITKVVPIXXXX 661
                ++ + V T ELYPT  R    G      + G +L   I       T +VPI    
Sbjct: 291 --AGLFSIIFVYTTELYPTVIRNIGMGTCLFWARLGGVLAPQINQLGGNSTVLVPIMVFG 464

Query: 662 XXXXXXXXXXXRLPETREQVL 682
                       LPET +Q L
Sbjct: 465 CMMLLGGVLLFLLPETHKQKL 527
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|21312430|ref|NP_082381.1| aarF domain containing
kinase 1 [Mus musculus]
         (525 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

35717                                                                  46   4e-05
06078                                                                  31   1.0  
07477                                                                  31   1.4  
>35717
          Length = 686

 Score = 45.8 bits (107), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 30/104 (28%), Positives = 52/104 (50%), Gaps = 3/104 (2%)
 Frame = -3

Query: 173 VAVKVQHPKVQAQSSKDILLMEVLVLAVKQLFPDFEFMWL---VDEAKKNLPLELDFLNE 229
           VAVKV HP V  Q  +D+ LM+V+   ++ L P   ++ L   V E   ++  ++D  +E
Sbjct: 339 VAVKVLHPGVAGQFHRDLKLMKVMASVLETLIPSLRWLNLTECVREFSLSMSKQMDMKHE 160

Query: 230 GRNAEKVAHMLRHFDFLKVPQIHWELSTKRVLLMEFVEGGQVND 273
            R  ++         F+K+P     L  + +L+  F EG  ++D
Sbjct: 159 ARCLKRFHADFADVPFIKIPVPIMSLVRQNILVESFEEGEPISD 28
>06078
          Length = 1315

 Score = 31.2 bits (69), Expect = 1.0,   Method: Compositional matrix adjust.
 Identities = 23/71 (32%), Positives = 37/71 (52%), Gaps = 2/71 (2%)
 Frame = +1

Query: 401 TEDSEIRNNAACYLPEISQLL--NHVPRQMLLILKTNDLLRSIETTLGTRSSASSFLNMS 458
           TE++EI NNA CY  +   +L   HV  Q   + +T+  L+    +L   S++ S+ + S
Sbjct: 268 TEETEIFNNAPCYNEQEPPVLENEHVQXQPFCVPRTSSNLKPXTESLD--SNSVSYSDQS 441

Query: 459 RCCIRALAEHK 469
            CC+   A  K
Sbjct: 442 -CCVSIKASGK 471
>07477
          Length = 737

 Score = 30.8 bits (68), Expect = 1.4,   Method: Compositional matrix adjust.
 Identities = 13/40 (32%), Positives = 23/40 (57%), Gaps = 1/40 (2%)
 Frame = -3

Query: 374 YPLFACMLT-ARSWDSVKQGIGQAPVSATEDSEIRNNAAC 412
           + LF C  T ++ W  + QG+    V AT ++E++  A+C
Sbjct: 726 FHLFICCFTPSQLWFGLSQGVAAETVCATHETEVKVQASC 607
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|22122725|ref|NP_666294.1| kinesin light chain 3 [Mus
musculus]
         (508 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

29651                                                                  46   4e-05
>29651
          Length = 414

 Score = 45.8 bits (107), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 26/65 (40%), Positives = 37/65 (56%), Gaps = 1/65 (1%)
 Frame = -3

Query: 21  EELVRQTRQVVQGLEALRAEHHSLAGHLAEALAGPGPVAG-VELLEEKQQVVNHSLEAIE 79
           +E+   T+ VVQGLE L+ EHH +   L  +L       G   L+EEK  ++  SLE +E
Sbjct: 208 DEIATNTKTVVQGLETLKNEHHQILNSLLSSLKTIQQENGDSSLVEEKTNILRASLETLE 29

Query: 80  LGLGE 84
           LG+ E
Sbjct: 28  LGVSE 14
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6754168|ref|NP_034538.1| hyperpolarization-activated,
cyclic nucleotide-gated K+ 1 [Mus musculus]
         (910 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

08195                                                                  47   4e-05
18204                                                                  46   6e-05
27710                                                                  44   2e-04
19667                                                                  35   0.099
24780                                                                  35   0.15 
>08195
          Length = 2165

 Score = 47.0 bits (110), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 35/147 (23%), Positives = 69/147 (46%), Gaps = 5/147 (3%)
 Frame = -3

Query: 434  DEENILSELNDPLREEIVNFNCRKLVATMPLFANADPNFVTAMLSKLRFEVFQPGDYIIR 493
            DE+   +++ +P + +I       +V  + LF + DP  +  +L  +  +  QPG++II 
Sbjct: 1707 DEDGGEAKIVNP-KSDIQRQRLADVVKNILLFRSLDPEQMQEVLDAMFEKSVQPGEHIID 1531

Query: 494  EGAVGKKMYFIQHGVAGVITKSSKEMKLT----DGSYFGEICLLTKGRRTASVRADTYCR 549
            +G  G   Y I  G   +      + KL     +  +FGE+ L+    R A++ A +   
Sbjct: 1530 QGDDGDNFYVIDSGTYDIYVDVEGQAKLVGNYDNSGFFGELALMYNMPRAATIIASSTGT 1351

Query: 550  LYSLSVDNFNE-VLEEYPMMRRAFETV 575
            +++L    F   VL+     R+ +E++
Sbjct: 1350 IWALDRTTFRRIVLKTAFQKRKKYESL 1270

 Score = 41.6 bits (96), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 31/124 (25%), Positives = 51/124 (41%), Gaps = 14/124 (11%)
 Frame = -3

Query: 453  FNCRK----LVATMPLFANADPNFVTAMLSKLRFEVFQPGDYIIREGAVGKKMYFIQHGV 508
            F  RK    L+ ++PL  + D      +   L+   ++ G  II++G     MYF++ G 
Sbjct: 1299 FQKRKKYESLLESVPLLKSLDLYERMNVADALQTRTYEDGVQIIKQGDAADVMYFVESGQ 1120

Query: 509  AGVITKSSKEMK----------LTDGSYFGEICLLTKGRRTASVRADTYCRLYSLSVDNF 558
              +   + +             L  G YFGE+ L+T   R AS  A    +   L V  F
Sbjct: 1119 VRIAMTNKESTDPSAGETDVTVLEKGGYFGELALITHQPRAASAYAQGTVKCAVLDVHAF 940

Query: 559  NEVL 562
              ++
Sbjct: 939  ERLM 928
>18204
          Length = 429

 Score = 46.2 bits (108), Expect = 6e-05,   Method: Composition-based stats.
 Identities = 30/73 (41%), Positives = 38/73 (52%), Gaps = 8/73 (10%)
 Frame = -1

Query: 480 LRFEVFQPGDYIIREGAVGKKMYFIQHG-------VAGVITKSSKEM-KLTDGSYFGEIC 531
           L  + F  G++IIREG  G   + I  G       VAG   +  +E+ KL  G YFGE  
Sbjct: 213 LEIDFFHEGEFIIREGCTGDTFFLINKGEVRVTQTVAG--HEEPQEIRKLKRGDYFGEKA 40

Query: 532 LLTKGRRTASVRA 544
           LL + RRTAS  A
Sbjct: 39  LLGEDRRTASCIA 1

 Score = 30.8 bits (68), Expect = 2.7,   Method: Composition-based stats.
 Identities = 15/44 (34%), Positives = 25/44 (56%)
 Frame = -1

Query: 527 FGEICLLTKGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRR 570
           FGE+ +L    RTASV+A T  +++ L    F  ++ +  + RR
Sbjct: 426 FGELAILYNCTRTASVKAVTDVKVWVLDRQMFQAIMMKTGLQRR 295
>27710
          Length = 429

 Score = 44.3 bits (103), Expect = 2e-04,   Method: Composition-based stats.
 Identities = 31/123 (25%), Positives = 55/123 (44%)
 Frame = +2

Query: 491 IIREGAVGKKMYFIQHGVAGVITKSSKEMKLTDGSYFGEICLLTKGRRTASVRADTYCRL 550
           II++G  G   Y I  G   V   S     +++G  FGE+ L+    R A+VRA +  +L
Sbjct: 8   IIQQGDEGDNFYVIDVGEVDVFVNSELVTTISEGGSFGELALIYGTPRAATVRAKSDVKL 187

Query: 551 YSLSVDNFNEVLEEYPMMRRAFETVAIDRLDRIGKKNSILLQKFQKDLNTGVFNNQENEI 610
           + +  D++  +L    + +R      + R+  +   +          L T  F++ E  I
Sbjct: 188 WGIDRDSYRRILMGSTIRKRKMYEEFLSRVSILESLDKWERLTVADSLETCAFDDGET-I 364

Query: 611 LKQ 613
           +KQ
Sbjct: 365 VKQ 373
>19667
          Length = 442

 Score = 35.4 bits (80), Expect = 0.099,   Method: Compositional matrix adjust.
 Identities = 26/103 (25%), Positives = 38/103 (36%), Gaps = 2/103 (1%)
 Frame = +3

Query: 472 FVTAMLSKLRFEVFQPGDYIIREGAVGKKMYFIQHGVAGVITKSSKEMKLTDGSYFGEIC 531
           FV   L   R   F PG+ +I +G   + +Y++  G   V+        L  G  FG   
Sbjct: 33  FVPVALQTSRV-FFGPGEVLIHKGDAIRNIYYVCSGSLEVLKDEQVVAILGKGDLFGSDI 209

Query: 532 LLTK--GRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRRAF 572
                       VR+  YC L  ++     E L+ YP     F
Sbjct: 210 KFEDPVSISGGDVRSLAYCELLCINTQGLAECLQPYPDFSEKF 338
>24780
          Length = 572

 Score = 35.0 bits (79), Expect = 0.15,   Method: Composition-based stats.
 Identities = 14/30 (46%), Positives = 20/30 (66%)
 Frame = +3

Query: 537 RRTASVRADTYCRLYSLSVDNFNEVLEEYP 566
           RRTA VR+  Y  +++LS  +F E + EYP
Sbjct: 6   RRTADVRSSGYTNVFTLSKHDFEEAMNEYP 95
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6679245|ref|NP_032827.1| phosphodiesterase 6D,
cGMP-specific, rod, delta [Mus musculus]
         (150 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

19759                                                                  43   5e-05
07377                                                                  28   1.2  
13351                                                                  28   2.0  
33673                                                                  27   4.3  
05504                                                                  27   4.8  
16682                                                                  27   4.9  
02346                                                                  26   6.1  
>19759
          Length = 439

 Score = 42.7 bits (99), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 23/60 (38%), Positives = 36/60 (60%), Gaps = 1/60 (1%)
 Frame = +3

Query: 52  KILKCKAVSRELNFSSAE-QMEKFRLEQKVYFKGQCLEEWFFEFGFVIPNSTNTWQSLIE 110
           + LK K V   + F   + ++ KFR+ +K YF  + L+ + FEFGF IP+S NT + + E
Sbjct: 27  QFLKLKTVGATVEFVVGDKEVSKFRMVEKHYFHDRLLKCFDFEFGFCIPHSRNTVEHIYE 206
>07377
          Length = 466

 Score = 28.5 bits (62), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 16/41 (39%), Positives = 20/41 (48%), Gaps = 1/41 (2%)
 Frame = +1

Query: 20  MNLRDAETGKIL-WQGTEDLSVPGVEHEARVPKKILKCKAV 59
           M LR    G ++ WQG    +  GVE   R PK  L C+ V
Sbjct: 292 MILRAMSAGDLVSWQGHPC*TGLGVEPRPRAPKSPLGCRGV 414
>13351
          Length = 869

 Score = 27.7 bits (60), Expect = 2.0,   Method: Compositional matrix adjust.
 Identities = 15/49 (30%), Positives = 21/49 (42%)
 Frame = -3

Query: 42  GVEHEARVPKKILKCKAVSRELNFSSAEQMEKFRLEQKVYFKGQCLEEW 90
           G+ H +  P    KC   S  LNF+  E+ + F L +     G  L E 
Sbjct: 495 GIHHSSEKP---FKCDMCSMTLNFNHLEKHKSFHLSEGSIVNGNPLHEC 358
>33673
          Length = 448

 Score = 26.6 bits (57), Expect = 4.3,   Method: Compositional matrix adjust.
 Identities = 14/39 (35%), Positives = 18/39 (46%)
 Frame = -3

Query: 87  LEEWFFEFGFVIPNSTNTWQSLIEAAPESQMMPASVLTG 125
           L  W  E G V P   ++W  L     E ++  A VLTG
Sbjct: 200 LACWGVEXGLV*PEXLSSWVELCPTCFEGEVCEAGVLTG 84
>05504
          Length = 2039

 Score = 26.6 bits (57), Expect = 4.8,   Method: Compositional matrix adjust.
 Identities = 11/29 (37%), Positives = 15/29 (51%)
 Frame = -3

Query: 18  NWMNLRDAETGKILWQGTEDLSVPGVEHE 46
           +W N+R   +  ILWQ   DL   G+ H 
Sbjct: 756 SW*NMRVMGSSPILWQNLYDLIFSGMRHS 670
>16682
          Length = 621

 Score = 26.6 bits (57), Expect = 4.9,   Method: Compositional matrix adjust.
 Identities = 18/58 (31%), Positives = 26/58 (44%), Gaps = 3/58 (5%)
 Frame = +1

Query: 59  VSRELNFSSAEQMEKFRLEQKVYFKGQCLEEWFFEFG-FVIPNSTNT--WQSLIEAAP 113
           +SR  NF    +   F L ++++    CL    F+F  F  PN  N      LI +AP
Sbjct: 229 MSRNFNFLKTFKQFSFSLLKELHLVSSCLSSISFKFKLFFAPNRNNI*LTSCLIPSAP 402
>02346
          Length = 1181

 Score = 26.2 bits (56), Expect = 6.1,   Method: Compositional matrix adjust.
 Identities = 13/47 (27%), Positives = 19/47 (40%)
 Frame = +2

Query: 95  GFVIPNSTNTWQSLIEAAPESQMMPASVLTGNVIIETKFFDDDLLVS 141
           G ++   T TW  L+     S+  P  +    VII  K      +VS
Sbjct: 305 GRMLTQKTRTWSKLLRHGISSEEKPLKLRATKVIIPLKMLKSTFIVS 445
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6753242|ref|NP_033918.1| calbindin-28K [Mus musculus]
         (261 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

14594                                                                  44   5e-05
27864                                                                  40   0.001
03732                                                                  37   0.010
12214                                                                  34   0.059
05237                                                                  34   0.072
26019                                                                  33   0.094
20251                                                                  33   0.16 
14945                                                                  32   0.25 
08108                                                                  32   0.25 
38338                                                                  32   0.30 
22063                                                                  32   0.34 
01773                                                                  31   0.65 
26610                                                                  29   1.7  
03085                                                                  29   2.2  
19822                                                                  28   3.1  
01019                                                                  28   3.4  
15966                                                                  28   4.1  
06641                                                                  28   4.6  
33397                                                                  28   4.8  
01491                                                                  28   4.8  
17484                                                                  28   4.9  
17977                                                                  28   5.3  
30467                                                                  27   7.0  
>14594
          Length = 1014

 Score = 44.3 bits (103), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 35/124 (28%), Positives = 58/124 (46%), Gaps = 4/124 (3%)
 Frame = +3

Query: 102 EFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGK 161
           EF + +  +D D  G I T EL   ++ L +   +        E  D M+   D++ +G 
Sbjct: 444 EFKEAFSLFDKDGDGTITTSELGTVMRSLGQNPTEN-------ELQD-MINEVDADGNGT 599

Query: 162 LELTE----MARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKD 217
           ++  E    MAR +   +           C +E  +AF ++D+DGNGYI   EL  ++ +
Sbjct: 600 IDFEEFLHMMARKMKDTD-----------CEEELREAFRVFDKDGNGYISAAELRHVMTN 746

Query: 218 LCEK 221
           L EK
Sbjct: 747 LGEK 758
>27864
          Length = 343

 Score = 39.7 bits (91), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 32/111 (28%), Positives = 45/111 (40%)
 Frame = +1

Query: 108 RKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEM 167
           ++ D D SG I   EL+  L      +N T       E   LM+ +FD +N G +   E 
Sbjct: 34  QRIDKDRSGNISVNELQQAL------SNGTWTPFN-PETVRLMIGMFDRDNSGTINFQE- 189

Query: 168 ARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDL 218
                        FQ +     ++   F  YD+D +G ID NEL     DL
Sbjct: 190 -------------FQALWKYVTDWQNCFRSYDRDNSGSIDRNELKMPXPDL 303

 Score = 26.6 bits (57), Expect = 9.9,   Method: Compositional matrix adjust.
 Identities = 14/40 (35%), Positives = 22/40 (55%), Gaps = 4/40 (10%)
 Frame = +1

Query: 95  QQLKSCEEFMKTW----RKYDTDHSGFIETEELKNFLKDL 130
           Q+ ++  +++  W    R YD D+SG I+  ELK    DL
Sbjct: 184 QEFQALWKYVTDWQNCFRSYDRDNSGSIDRNELKMPXPDL 303
>03732
          Length = 1114

 Score = 36.6 bits (83), Expect = 0.010,   Method: Compositional matrix adjust.
 Identities = 30/104 (28%), Positives = 43/104 (41%)
 Frame = -1

Query: 108  RKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEM 167
            ++ D D SG I   EL+  L      +N T       E   LM+ +FD +N G +   E 
Sbjct: 1081 QRIDKDRSGNISVNELQQAL------SNGTWTPFN-PETVRLMIGMFDRDNSGTINFQE- 926

Query: 168  ARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENEL 211
                         FQ +     ++   F  YD+D +G ID NEL
Sbjct: 925  -------------FQALWKYVTDWQNCFRSYDRDNSGSIDRNEL 833

 Score = 33.5 bits (75), Expect = 0.095,   Method: Compositional matrix adjust.
 Identities = 26/116 (22%), Positives = 48/116 (41%), Gaps = 4/116 (3%)
 Frame = -1

Query: 95  QQLKSCEEFMKTW----RKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLM 150
           Q+ ++  +++  W    R YD D+SG I+  ELKN L     + +          + D++
Sbjct: 931 QEFQALWKYVTDWQNCFRSYDRDNSGSIDRNELKNALTGFGYRLSD--------RFFDVL 776

Query: 151 LKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYI 206
           +K FD    G +   +  +   V +                  +F  +DQD +G+I
Sbjct: 775 VKKFDRQGKGTVAFDDFIQCCVVLQT--------------LTTSFRTHDQDQDGWI 650
>12214
          Length = 654

 Score = 34.3 bits (77), Expect = 0.059,   Method: Compositional matrix adjust.
 Identities = 27/109 (24%), Positives = 43/109 (39%), Gaps = 32/109 (29%)
 Frame = -3

Query: 15  QFFEIWL----HFDADGSGYLEGKELQNLIQELLQARKKAGLELSPE------------- 57
           Q+ + W      +D++ SG +EG ELQ   Q++       G  +SP              
Sbjct: 574 QYIQQWRSTFERYDSNRSGSIEGNELQAAYQQM-------GFNVSPRFVQTVLYKFDHFG 416

Query: 58  ---------------MKSFVDQYGQRDDGKIGIVELAHVLPTEENFLLL 91
                          +KS  D + QRD G  G+V +A+     E+FL +
Sbjct: 415 RRSLTLDNFIQSCVMLKSLTDAFRQRDTGSTGVVNMAY-----EDFLTM 284

 Score = 31.2 bits (69), Expect = 0.44,   Method: Compositional matrix adjust.
 Identities = 18/70 (25%), Positives = 33/70 (47%)
 Frame = -3

Query: 149 LMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDE 208
           LM+ +FD +  G +++ E              FQ +    +++   FE YD + +G I+ 
Sbjct: 643 LMIGMFDRDMSGTIDINE--------------FQSLWQYIQQWRSTFERYDSNRSGSIEG 506

Query: 209 NELDALLKDL 218
           NEL A  + +
Sbjct: 505 NELQAAYQQM 476
>05237
          Length = 472

 Score = 33.9 bits (76), Expect = 0.072,   Method: Compositional matrix adjust.
 Identities = 14/32 (43%), Positives = 23/32 (71%)
 Frame = +3

Query: 190 EFNKAFELYDQDGNGYIDENELDALLKDLCEK 221
           E  +AF ++D+DGNG+I  +EL  ++ +L EK
Sbjct: 30  ELREAFRVFDKDGNGFISASELRHVMTNLGEK 125
>26019
          Length = 1561

 Score = 33.5 bits (75), Expect = 0.094,   Method: Compositional matrix adjust.
 Identities = 33/128 (25%), Positives = 59/128 (46%)
 Frame = +2

Query: 105 KTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLEL 164
           K +RK D D+SG +  +E  + L +L +                 ++ +FD++ +G+++ 
Sbjct: 110 KRFRKLDLDNSGSLSIDEFMS-LPELQQNP-----------LVQRVIDIFDTDGNGEVDF 253

Query: 165 TEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCEKNKQ 224
            E    +     F +K  G K     F  AF++YD D +GYI   EL  +LK +   N +
Sbjct: 254 KEFIEGI---SQFSVK--GDKESKLRF--AFKIYDMDKDGYISNGELFQVLKMMVGNNLK 412

Query: 225 ELDINNIT 232
           +  +  I 
Sbjct: 413 DTQLQQIV 436
>20251
          Length = 2203

 Score = 32.7 bits (73), Expect = 0.16,   Method: Compositional matrix adjust.
 Identities = 35/141 (24%), Positives = 54/141 (38%), Gaps = 6/141 (4%)
 Frame = +3

Query: 87  NFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEY 146
           N   +F   Q+   +EF + +   D +  GFI+ E+L + L  L                
Sbjct: 126 NVFAMFDQSQI---QEFKEAFNMIDQNRDGFIDKEDLGDMLASL---------------- 248

Query: 147 TDLMLKLFDSNNDGKLELTEMARLLPVQENF--LLKFQGIKMCGKE----FNKAFELYDQ 200
                      N  + +L EM    P   NF   L   G K+ G +       AF  +D+
Sbjct: 249 ---------GKNPTEGQLDEMMNXAPGPINFTMFLTMFGDKLNGTDPEDVIKNAFACFDE 401

Query: 201 DGNGYIDENELDALLKDLCEK 221
           DG G I E+ L  LL  + ++
Sbjct: 402 DGKGVIQEDRLRELLTTMGDR 464
>14945
          Length = 1337

 Score = 32.0 bits (71), Expect = 0.25,   Method: Compositional matrix adjust.
 Identities = 15/37 (40%), Positives = 24/37 (64%)
 Frame = +1

Query: 189 KEFNKAFELYDQDGNGYIDENELDALLKDLCEKNKQE 225
           +E  +AF+L+D DG+G ID  EL   ++ L  + K+E
Sbjct: 112 QEIREAFDLFDADGSGTIDAKELKVAMRALGFEPKKE 222

 Score = 30.8 bits (68), Expect = 0.57,   Method: Compositional matrix adjust.
 Identities = 25/94 (26%), Positives = 47/94 (50%)
 Frame = +1

Query: 23  FDADGSGYLEGKELQNLIQELLQARKKAGLELSPEMKSFVDQYGQRDDGKIGIVELAHVL 82
           FDADGSG ++ KEL+  ++ L    KK  ++   +M + +D+ G       G ++    L
Sbjct: 139 FDADGSGTIDAKELKVAMRALGFEPKKEEIK---KMIAEIDKEG------TGTIDFNDFL 291

Query: 83  PTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSG 116
                 ++  +  +  + EE +K +R +D D +G
Sbjct: 292 T-----IMTQKMSEKDAKEEILKAFRLFDDDETG 378
>08108
          Length = 818

 Score = 32.0 bits (71), Expect = 0.25,   Method: Compositional matrix adjust.
 Identities = 18/60 (30%), Positives = 34/60 (56%)
 Frame = +2

Query: 108 RKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEM 167
           +KYD+D +G I+T+E +  ++          D  +LA+   LM K  D++ DG++  +E+
Sbjct: 254 KKYDSDSNGDIDTDEFRKLVE-------GESDVARLAQSA-LMFKSLDADGDGQITASEI 409
>38338
          Length = 463

 Score = 31.6 bits (70), Expect = 0.30,   Method: Compositional matrix adjust.
 Identities = 13/31 (41%), Positives = 21/31 (67%)
 Frame = -2

Query: 190 EFNKAFELYDQDGNGYIDENELDALLKDLCE 220
           EF +AF L+D+DG+G I   EL  +++ L +
Sbjct: 165 EFKEAFSLFDKDGDGTITTKELGTVMRSLGQ 73
>22063
          Length = 688

 Score = 31.6 bits (70), Expect = 0.34,   Method: Compositional matrix adjust.
 Identities = 15/37 (40%), Positives = 24/37 (64%)
 Frame = +3

Query: 189 KEFNKAFELYDQDGNGYIDENELDALLKDLCEKNKQE 225
           +E  +AF+L+D DG+G ID  EL   ++ L  + K+E
Sbjct: 171 QEIREAFDLFDADGSGTIDAKELKVAMRALGFEPKKE 281

 Score = 29.3 bits (64), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 25/94 (26%), Positives = 47/94 (50%)
 Frame = +3

Query: 23  FDADGSGYLEGKELQNLIQELLQARKKAGLELSPEMKSFVDQYGQRDDGKIGIVELAHVL 82
           FDADGSG ++ KEL+  ++ L    KK  ++   +M + +D+ G       G ++    L
Sbjct: 198 FDADGSGTIDAKELKVAMRALGFEPKKEEIK---KMIAEIDKEG------TGTIDFNDFL 350

Query: 83  PTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSG 116
                 ++  +  +  + EE +K +R +D D +G
Sbjct: 351 T-----IMTQKMSEKDAKEEILKAFRLFDDDETG 437
>01773
          Length = 1950

 Score = 30.8 bits (68), Expect = 0.65,   Method: Compositional matrix adjust.
 Identities = 27/124 (21%), Positives = 61/124 (49%), Gaps = 1/124 (0%)
 Frame = +1

Query: 99  SCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDS-N 157
           + + + + +++ D ++ G++E +EL+    +L ++   ++ D+++A+        FD   
Sbjct: 148 NTDAYKQLFKEADKNNDGYLEIKELR----ELFKRNGSSLSDSQIAD----TFVFFDGPR 303

Query: 158 NDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKD 217
            D ++            E F      I M  ++  + F+  D+ G+GY+D +EL ALL +
Sbjct: 304 GDKRITF----------EXFCKGLDQIVMFVQKLAELFKAKDKSGDGYLDRDELKALLDE 453

Query: 218 LCEK 221
             +K
Sbjct: 454 SGQK 465

 Score = 29.3 bits (64), Expect = 1.8,   Method: Compositional matrix adjust.
 Identities = 38/150 (25%), Positives = 63/150 (42%)
 Frame = +1

Query: 18  EIWLHFDADGSGYLEGKELQNLIQELLQARKKAGLELSPEMKSFVDQYGQRDDGKIGIVE 77
           +++   D +  GYLE KEL+ L +     R  + L  S    +FV   G R D +I    
Sbjct: 166 QLFKEADKNNDGYLEIKELRELFK-----RNGSSLSDSQIADTFVFFDGPRGDKRITFEX 330

Query: 78  LAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKT 137
               L      +++F        ++  + ++  D    G+++ +ELK  L +  +K   T
Sbjct: 331 FCKGLDQ----IVMF-------VQKLAELFKAKDKSGDGYLDRDELKALLDESGQKF--T 471

Query: 138 VDDTKLAEYTDLMLKLFDSNNDGKLELTEM 167
            DD         +LK  D NND K+   E 
Sbjct: 472 ADDVS------AILKSADKNNDNKICFEEF 543
>26610
          Length = 455

 Score = 29.3 bits (64), Expect = 1.7,   Method: Compositional matrix adjust.
 Identities = 25/100 (25%), Positives = 44/100 (44%), Gaps = 29/100 (29%)
 Frame = +3

Query: 151 LKLFDSNNDGKLELTEMA----------------RLLP---------VQEN----FLLKF 181
            +LFD++NDGK+  +E+                 RLL          V  N     +   
Sbjct: 60  FELFDTDNDGKIAASEVGTAIRSLGHVVTDSDLRRLLSKAGIEPHGKVDMNRFRQLVQPL 239

Query: 182 QGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCEK 221
           QG+    K+ ++AF   D++G+G++   EL  LL  + ++
Sbjct: 240 QGVNYT-KQLDEAFNTIDKEGSGFVMATELRHLLTHMGDR 356
>03085
          Length = 1081

 Score = 28.9 bits (63), Expect = 2.2,   Method: Compositional matrix adjust.
 Identities = 15/45 (33%), Positives = 24/45 (53%), Gaps = 3/45 (6%)
 Frame = +2

Query: 65  YGQRDDGKIGIVELA---HVLPTEENFLLLFRCQQLKSCEEFMKT 106
           Y  ++ G+  + EL+   + + TEE    +F C Q + CE F KT
Sbjct: 137 YSPKEHGERSVWELSVKHNSILTEEFSXFIFPCSQDRRCEHFRKT 271
>19822
          Length = 431

 Score = 28.5 bits (62), Expect = 3.1,   Method: Compositional matrix adjust.
 Identities = 24/78 (30%), Positives = 37/78 (47%), Gaps = 5/78 (6%)
 Frame = -3

Query: 177 FLLKFQ---GIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCEKNKQELD--INNI 231
           F LK +   G+ MCG  F+K+  L +   +   ++ E       +CE    E D   NN 
Sbjct: 402 FYLKIEKRLGV*MCGAAFSKSHNLKEHLSSHVDNKKEF------VCE----ECDDVFNNA 253

Query: 232 TTYKKNIMALSDGGKLYR 249
             +KK+I ++  GGK  R
Sbjct: 252 FQFKKHIRSVHSGGKGQR 199
>01019
          Length = 1705

 Score = 28.1 bits (61), Expect = 3.4,   Method: Compositional matrix adjust.
 Identities = 11/25 (44%), Positives = 18/25 (72%)
 Frame = +1

Query: 197 LYDQDGNGYIDENELDALLKDLCEK 221
           ++D+DGNG+I   EL  ++ +L EK
Sbjct: 43  VFDKDGNGFISAAELRHVMTNLGEK 117
>15966
          Length = 362

 Score = 28.1 bits (61), Expect = 4.1,   Method: Compositional matrix adjust.
 Identities = 15/41 (36%), Positives = 23/41 (56%)
 Frame = +2

Query: 175 ENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALL 215
           E F      I M  ++  + F+  D+ G+GY+D +EL ALL
Sbjct: 92  EEFCKGLDQIVMFVQKLAELFKAKDKSGDGYLDRDELKALL 214
>06641
          Length = 726

 Score = 27.7 bits (60), Expect = 4.6,   Method: Compositional matrix adjust.
 Identities = 22/92 (23%), Positives = 43/92 (46%), Gaps = 13/92 (14%)
 Frame = +1

Query: 133 KANKTVDDTKL-------------AEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLL 179
           +ANKTVD  ++             AE  D++ ++ +    G +      + LP+    L+
Sbjct: 229 EANKTVDVREVGTIIRSLGCCPSEAELHDMLAEIEEEEPTGYIRF---EKFLPMMTKVLM 399

Query: 180 KFQGIKMCGKEFNKAFELYDQDGNGYIDENEL 211
           + +   +   +  KAF++ D +G GY+ + EL
Sbjct: 400 ERRYKAVPEDQIVKAFQVLDVEGRGYLLQEEL 495
>33397
          Length = 1723

 Score = 27.7 bits (60), Expect = 4.8,   Method: Compositional matrix adjust.
 Identities = 15/45 (33%), Positives = 23/45 (51%), Gaps = 1/45 (2%)
 Frame = +2

Query: 128 KDLLEKANKTVDDTKLAEYT-DLMLKLFDSNNDGKLELTEMARLL 171
           ++      KTV    L E+  D++  LFD NNDG+L   E   ++
Sbjct: 710 RETFHHVAKTVAMADLTEHVIDVVFTLFDENNDGELSNKEFVSVM 844
>01491
          Length = 1707

 Score = 27.7 bits (60), Expect = 4.8,   Method: Compositional matrix adjust.
 Identities = 17/58 (29%), Positives = 27/58 (46%)
 Frame = +2

Query: 192 NKAFELYDQDGNGYIDENELDALLKDLCEKNKQELDINNITTYKKNIMALSDGGKLYR 249
           ++ F L+D+ GNG +   EL  + K L  + + E   N  T + +     S G  L R
Sbjct: 137 SQTFHLFDKKGNGTVSTKELANVFKSLGLQVEDEKLKNGQTLWTRMPPGSSRGNSLSR 310
>17484
          Length = 471

 Score = 27.7 bits (60), Expect = 4.9,   Method: Compositional matrix adjust.
 Identities = 14/33 (42%), Positives = 20/33 (60%), Gaps = 4/33 (12%)
 Frame = -1

Query: 198 YDQDGNGYIDENELDALLK----DLCEKNKQEL 226
           YDQDGNG I  NE  ++++     L EK  +E+
Sbjct: 465 YDQDGNGKITRNEFRSVVRMLGHSLSEKELEEM 367

 Score = 27.3 bits (59), Expect = 7.2,   Method: Compositional matrix adjust.
 Identities = 12/33 (36%), Positives = 19/33 (57%)
 Frame = -3

Query: 189 KEFNKAFELYDQDGNGYIDENELDALLKDLCEK 221
           KE   AF  +DQ+G+G I  +EL   +  + +K
Sbjct: 271 KEMRDAFRAFDQNGDGVISISELRQAMAKMGQK 173
>17977
          Length = 445

 Score = 27.7 bits (60), Expect = 5.3,   Method: Compositional matrix adjust.
 Identities = 13/36 (36%), Positives = 21/36 (58%)
 Frame = +3

Query: 193 KAFELYDQDGNGYIDENELDALLKDLCEKNKQELDI 228
           +AF  YD+DG G ID ++    L++ C K    +D+
Sbjct: 231 RAFRFYDKDGKGKIDIDD----LREACRKFDVPIDV 326
>30467
          Length = 1046

 Score = 27.3 bits (59), Expect = 7.0,   Method: Compositional matrix adjust.
 Identities = 13/43 (30%), Positives = 21/43 (48%)
 Frame = +1

Query: 217 DLCEKNKQELDINNITTYKKNIMALSDGGKLYRTDLALILSAG 259
           D+C K K +L I+N+  +    +    G  LY+ DL  I +  
Sbjct: 19  DIC*KTKDKLTIDNLLCFMYYALCFFQGKALYKYDLHYITNTA 147
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|94393767|ref|XP_999995.1| PREDICTED: similar to RIKEN
cDNA C920006C10 isoform 5 [Mus musculus]
         (780 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

34495                                                                  46   5e-05
14947                                                                  32   1.0  
35057                                                                  31   1.9  
30119                                                                  29   7.0  
12138                                                                  29   8.7  
>34495
          Length = 267

 Score = 46.2 bits (108), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 30/85 (35%), Positives = 44/85 (51%), Gaps = 4/85 (4%)
 Frame = -2

Query: 291 GSVGPTVLEMFNTLLRQLRLSIDYALTGSYDGAVSLGSKIIKEHEECMFQEAVIKTIGSF 350
           GS+GP+VLE+FN LLR LR+S+D           S GS   +   E  FQ+   +    +
Sbjct: 218 GSIGPSVLEVFNNLLRHLRISVD-----------SKGSNQAQSTAEVHFQDDHRQ---HY 81

Query: 351 ASTLPTY----QRSEVILFIMSKVP 371
            S LPT     ++   ++F+M K P
Sbjct: 80  RSVLPTICLTTRKLRSLMFVMGKFP 6
>14947
          Length = 1158

 Score = 32.0 bits (71), Expect = 1.0,   Method: Compositional matrix adjust.
 Identities = 19/77 (24%), Positives = 37/77 (48%)
 Frame = +2

Query: 587 VIETRKKEAPYMLLRTCCCGPVSLQHDSDFLFRQSKISEVLGGSGYNSDRLCLPYIPQLT 646
           V  +R     + LL    CGP  L+ D+DFL  +  ++  L  S Y++       + +L+
Sbjct: 242 VHASRGHHPSHPLLSNPWCGPERLEKDADFLTGKVNVTSHLKISAYDAHSKYGNLLKKLS 421

Query: 647 DEDRLSKRKSIGETISL 663
           D     ++K + E++ +
Sbjct: 422 DFKPAERKKIVDESLKV 472
>35057
          Length = 831

 Score = 31.2 bits (69), Expect = 1.9,   Method: Compositional matrix adjust.
 Identities = 15/43 (34%), Positives = 23/43 (53%)
 Frame = -1

Query: 106 FFVSRFSEMCHSSHDDLEIKTKIRMSGIKGLQGVVRKTVNDEL 148
           +   R S  CH SHD + I+      G+ G  G++  +V+DEL
Sbjct: 390 WLCRRCSAFCHGSHDLIHIQCG---EGVAGQHGLLDVSVSDEL 271
>30119
          Length = 381

 Score = 29.3 bits (64), Expect = 7.0,   Method: Composition-based stats.
 Identities = 14/38 (36%), Positives = 22/38 (57%), Gaps = 2/38 (5%)
 Frame = +3

Query: 92  NIEEDTPSYHRSYDFFVSRFSEMCHSSHD--DLEIKTK 127
           NI+ D P Y  S     +R+ E+C   HD  ++EI+T+
Sbjct: 108 NIDTDNPRYDISIQVATTRYIELCIHYHDRSNIEIRTE 221
>12138
          Length = 829

 Score = 28.9 bits (63), Expect = 8.7,   Method: Compositional matrix adjust.
 Identities = 35/120 (29%), Positives = 58/120 (48%), Gaps = 6/120 (5%)
 Frame = -2

Query: 373 RALYCHPAETMSLAYRENRNRLTQIMLLKSLLQVSTGFQCNNMMSALPSNFLDRLLSTAL 432
           R +Y     T+ LAY+ +RN+  +++L + L+Q  T               LD  L + L
Sbjct: 741 RCMYVAKFSTLLLAYKTSRNKNLELIL*Q-LIQ*KTR--------------LDFFLPSIL 607

Query: 433 MEDAEIRLF---VLEILISFIDRHG-NRHKFS--TISTLGDISVLKLKVDKCSRQDTVFM 486
            E+ ++R+    +L+IL+ FI + G N   FS     T+ D  +L +K   C R   VF+
Sbjct: 606 QEN-DVRVLSICILQILV*FITKEGCNTDLFS*CFSKTVIDHFILLVKNSSCPRYCGVFL 430
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|118130807|ref|NP_080440.2| intracellular
membrane-associated calcium-independent phospholipase A2 gamma [Mus
musculus]
         (776 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

32936                                                                  46   6e-05
02555                                                                  31   1.6  
07501                                                                  31   2.1  
03297                                                                  31   2.3  
30939                                                                  30   5.1  
00319                                                                  29   6.8  
35102                                                                  29   7.5  
38077                                                                  28   9.5  
>32936
          Length = 499

 Score = 46.2 bits (108), Expect = 6e-05,   Method: Compositional matrix adjust.
 Identities = 26/47 (55%), Positives = 35/47 (74%)
 Frame = -3

Query: 398 KIIPYLLRLRQVKDETLQAAVREILALIGYVDPVKGRGIRILTIDGG 444
           K++P LL++ +  +E L+   RE LAL+GY  PV GRGIRILT+DGG
Sbjct: 221 KVVPLLLQMLESPEEELKEEAREALALLGYTQPVNGRGIRILTLDGG 81
>02555
          Length = 1775

 Score = 31.2 bits (69), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 29/97 (29%), Positives = 44/97 (45%), Gaps = 3/97 (3%)
 Frame = -2

Query: 246 TVADRPDSESPLEVKDKLSSPTQMPEAHPVSAKQSIANFLSRPTEGVQ---ALVGGYIGG 302
           T+  R D    L ++D  +S  ++P     S+K+++ NF     E +Q   AL    I  
Sbjct: 679 TIFSRYDKHRQLILEDIFASLARLP-----SSKRNLRNFRLNSEESIQMVTALALQLIQC 515

Query: 303 LVPKLKSDPKSPPEEQEVSAKTEQAVNKDKKAEEKKR 339
           +V     DP SP  EQE         +KD K ++ KR
Sbjct: 514 VVKLPSQDPSSPQPEQE---------SKDNKDKDPKR 431
>07501
          Length = 494

 Score = 30.8 bits (68), Expect = 2.1,   Method: Compositional matrix adjust.
 Identities = 28/95 (29%), Positives = 44/95 (46%), Gaps = 3/95 (3%)
 Frame = +2

Query: 246 TVADRPDSESPLEVKDKLSSPTQMPEAHPVSAKQSIANFLSRPTEGVQ---ALVGGYIGG 302
           T+  R D    L ++D  +S  ++P     S+K+++ NF     E +Q   AL    I  
Sbjct: 155 TIFSRYDKHRQLILEDIFASLARLP-----SSKRNLRNFRLNSEESIQMVTALALQLIQC 319

Query: 303 LVPKLKSDPKSPPEEQEVSAKTEQAVNKDKKAEEK 337
           +V     DP SP  EQE       + +KD K ++K
Sbjct: 320 VVKLPSQDPSSPQPEQE-------SKDKDPKRQQK 403
>03297
          Length = 2712

 Score = 30.8 bits (68), Expect = 2.3,   Method: Compositional matrix adjust.
 Identities = 9/15 (60%), Positives = 14/15 (93%)
 Frame = -2

Query: 27   KQLHFVCSKQYWRMN 41
            + +HFVC++QYWR+N
Sbjct: 1208 ENMHFVCTEQYWRIN 1164
>30939
          Length = 454

 Score = 29.6 bits (65), Expect = 5.1,   Method: Composition-based stats.
 Identities = 13/29 (44%), Positives = 18/29 (62%), Gaps = 2/29 (6%)
 Frame = -1

Query: 42  HVNVHREFHTSKKSCKWNRSEA--HCSKH 68
           HV+ HR  HT+K +C   R+ A  H +KH
Sbjct: 370 HVDTHRSAHTNKATCTHTRAHACTHANKH 284
>00319
          Length = 379

 Score = 29.3 bits (64), Expect = 6.8,   Method: Composition-based stats.
 Identities = 20/59 (33%), Positives = 27/59 (45%)
 Frame = -2

Query: 58  WNRSEAHCSKHWHSPSNHGLHFGIVRLSTSAPKGLTKVSIHMSRIKSTLNSVSKAIFGS 116
           + RSE HC  H H  + HG+     RL   A    TKV I +  +K  +  V  A+  S
Sbjct: 363 YQRSELHCHTHIH--TRHGISSEEKRLKLRA----TKVIIPLKNVKIYIYCVQTAVLHS 205
>35102
          Length = 687

 Score = 28.9 bits (63), Expect = 7.5,   Method: Composition-based stats.
 Identities = 22/74 (29%), Positives = 32/74 (43%), Gaps = 26/74 (35%)
 Frame = +2

Query: 21  CGKQ--RSKQLHF--------------VCSKQYWRMNHVNVHREFHTSKKS--C-----K 57
           CG++  R  QLH               VC K + +  H+ +H   HT +K   C     K
Sbjct: 221 CGERFFRKDQLHVHRRNHTGIHPFTCSVCGKHFQKNKHLTIHTRLHTGEKPFVCDICGDK 400

Query: 58  WNRSEA---HCSKH 68
           ++RS+A   H  KH
Sbjct: 401 FHRSDALFIHKKKH 442
>38077
          Length = 531

 Score = 28.5 bits (62), Expect = 9.5,   Method: Composition-based stats.
 Identities = 18/64 (28%), Positives = 33/64 (51%)
 Frame = +1

Query: 316 EEQEVSAKTEQAVNKDKKAEEKKRVLLQQEKIIARVSIDNRTRALVQALRRTADPKLCIT 375
           EEQ +    E ++N  K  +E K   LQ EKI+  +++ +  RA+  ++    D  L + 
Sbjct: 76  EEQILDDIREASLNVTKPFQETK-AFLQNEKIMLEMALADAXRAMHGSMHSLMDADLIME 252

Query: 376 RVEE 379
           R+ +
Sbjct: 253 RLHK 264
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|34098931|ref|NP_031612.1| calbindin 2 [Mus musculus]
         (271 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

14594                                                                  44   7e-05
27864                                                                  43   1e-04
03732                                                                  41   6e-04
26019                                                                  39   0.003
14945                                                                  38   0.005
22063                                                                  37   0.012
00167                                                                  35   0.028
05237                                                                  35   0.038
32088                                                                  35   0.044
08380                                                                  34   0.073
11425                                                                  32   0.27 
33397                                                                  32   0.30 
12214                                                                  32   0.38 
14366                                                                  31   0.67 
03616                                                                  30   0.71 
01491                                                                  30   0.76 
08108                                                                  30   1.0  
26610                                                                  30   1.2  
01019                                                                  28   3.3  
04067                                                                  28   3.5  
28531                                                                  28   3.9  
32241                                                                  28   3.9  
01773                                                                  28   4.5  
15966                                                                  27   7.3  
08051                                                                  27   7.7  
>14594
          Length = 1014

 Score = 43.9 bits (102), Expect = 7e-05,   Method: Compositional matrix adjust.
 Identities = 38/123 (30%), Positives = 56/123 (45%), Gaps = 2/123 (1%)
 Frame = +3

Query: 110 AEFMEAWRKYDTDRSGYIEANELKGFLSDLLKKANRPYDEPKLQEYTQTILRMFDLNGDG 169
           AEF EA+  +D D  G I  +EL   +  L      P  E +LQ+    +    D +G+G
Sbjct: 441 AEFKEAFSLFDKDGDGTITTSELGTVMRSL---GQNPT-ENELQDMINEV----DADGNG 596

Query: 170 KLGLSEMSRLLPVQENFLLKFQGMKLTS--EEFNAIFTFYDKDGSGYIDENELDALLKDL 227
            +   E   ++          + MK T   EE    F  +DKDG+GYI   EL  ++ +L
Sbjct: 597 TIDFEEFLHMMA---------RKMKDTDCEEELREAFRVFDKDGNGYISAAELRHVMTNL 749

Query: 228 YEK 230
            EK
Sbjct: 750 GEK 758

 Score = 32.7 bits (73), Expect = 0.18,   Method: Compositional matrix adjust.
 Identities = 23/77 (29%), Positives = 39/77 (50%)
 Frame = +3

Query: 17  TASQFLEIWKHFDADGNGYIEGKELENFFQELEKARKGSGMMSKSDNFGEKMKEFMQKYD 76
           T ++  ++    DADGNG I+    E F   +  ARK      K  +  E+++E  + +D
Sbjct: 543 TENELQDMINEVDADGNGTID---FEEFLHMM--ARK-----MKDTDCEEELREAFRVFD 692

Query: 77  KNSDGKIEMAELAQILP 93
           K+ +G I  AEL  ++ 
Sbjct: 693 KDGNGYISAAELRHVMT 743

 Score = 30.4 bits (67), Expect = 0.76,   Method: Compositional matrix adjust.
 Identities = 24/87 (27%), Positives = 36/87 (41%), Gaps = 9/87 (10%)
 Frame = +3

Query: 23  EIWKHFDADGNGYIEGKELENFFQELEKARKGSGMMSKSDNFGEKMK-----EFMQKYDK 77
           E ++ FD DGNGYI   EL +                   N GEK+      E +++ D 
Sbjct: 672 EAFRVFDKDGNGYISAAELRHVMT----------------NLGEKLTDEEVDEMIKEADL 803

Query: 78  NSDGKIEMAELAQIL----PTEENFLL 100
           + DG +   E   ++    P+E   LL
Sbjct: 804 DGDGMVNYEEFVTMMTAK*PSEGTRLL 884
>27864
          Length = 343

 Score = 43.1 bits (100), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 33/111 (29%), Positives = 46/111 (41%)
 Frame = +1

Query: 117 RKYDTDRSGYIEANELKGFLSDLLKKANRPYDEPKLQEYTQTILRMFDLNGDGKLGLSEM 176
           ++ D DRSG I  NEL+  LS+       P       E  + ++ MFD +  G +   E 
Sbjct: 34  QRIDKDRSGNISVNELQQALSNGTWTPFNP-------ETVRLMIGMFDRDNSGTINFQE- 189

Query: 177 SRLLPVQENFLLKFQGMKLTSEEFNAIFTFYDKDGSGYIDENELDALLKDL 227
                        FQ +     ++   F  YD+D SG ID NEL     DL
Sbjct: 190 -------------FQALWKYVTDWQNCFRSYDRDNSGSIDRNELKMPXPDL 303

 Score = 30.0 bits (66), Expect = 0.95,   Method: Compositional matrix adjust.
 Identities = 27/116 (23%), Positives = 45/116 (38%), Gaps = 12/116 (10%)
 Frame = +1

Query: 36  IEGKELENFFQELEKARKGS------------GMMSKSDNFGEKMKEFMQKYDKNSDGKI 83
           ++   L   FQ ++K R G+            G  +  +   E ++  +  +D+++ G I
Sbjct: 4   VDPNFLAGIFQRIDKDRSGNISVNELQQALSNGTWTPFN--PETVRLMIGMFDRDNSGTI 177

Query: 84  EMAELAQILPTEENFLLCFRQHVGSSAEFMEAWRKYDTDRSGYIEANELKGFLSDL 139
              E   +     ++  CFR               YD D SG I+ NELK    DL
Sbjct: 178 NFQEFQALWKYVTDWQNCFR--------------SYDRDNSGSIDRNELKMPXPDL 303
>03732
          Length = 1114

 Score = 40.8 bits (94), Expect = 6e-04,   Method: Compositional matrix adjust.
 Identities = 31/104 (29%), Positives = 44/104 (42%)
 Frame = -1

Query: 117  RKYDTDRSGYIEANELKGFLSDLLKKANRPYDEPKLQEYTQTILRMFDLNGDGKLGLSEM 176
            ++ D DRSG I  NEL+  LS+       P       E  + ++ MFD +  G +   E 
Sbjct: 1081 QRIDKDRSGNISVNELQQALSNGTWTPFNP-------ETVRLMIGMFDRDNSGTINFQE- 926

Query: 177  SRLLPVQENFLLKFQGMKLTSEEFNAIFTFYDKDGSGYIDENEL 220
                         FQ +     ++   F  YD+D SG ID NEL
Sbjct: 925  -------------FQALWKYVTDWQNCFRSYDRDNSGSIDRNEL 833

 Score = 34.7 bits (78), Expect = 0.041,   Method: Compositional matrix adjust.
 Identities = 27/127 (21%), Positives = 51/127 (40%), Gaps = 1/127 (0%)
 Frame = -1

Query: 66  EKMKEFMQKYDKNSDGKIEMAELAQILPTEENFLLCFRQHVGSSAEFMEAWRKYDTDRSG 125
           E ++  +  +D+++ G I   E   +     ++  CFR               YD D SG
Sbjct: 991 ETVRLMIGMFDRDNSGTINFQEFQALWKYVTDWQNCFR--------------SYDRDNSG 854

Query: 126 YIEANELKGFLSDL-LKKANRPYDEPKLQEYTQTILRMFDLNGDGKLGLSEMSRLLPVQE 184
            I+ NELK  L+    + ++R +D          +++ FD  G G +   +  +   V +
Sbjct: 853 SIDRNELKNALTGFGYRLSDRFFD---------VLVKKFDRQGKGTVAFDDFIQCCVVLQ 701

Query: 185 NFLLKFQ 191
                F+
Sbjct: 700 TLTTSFR 680
>26019
          Length = 1561

 Score = 38.5 bits (88), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 34/128 (26%), Positives = 55/128 (42%), Gaps = 2/128 (1%)
 Frame = +2

Query: 116 WRKYDTDRSGYIEANELKGFLSDLLKKANRPYDEPKLQE--YTQTILRMFDLNGDGKLGL 173
           +RK D D SG +  +E                  P+LQ+    Q ++ +FD +G+G++  
Sbjct: 116 FRKLDLDNSGSLSIDEFMSL--------------PELQQNPLVQRVIDIFDTDGNGEVDF 253

Query: 174 SEMSRLLPVQENFLLKFQGMKLTSEEFNAIFTFYDKDGSGYIDENELDALLKDLYEKNKK 233
            E      ++       +G K +   F   F  YD D  GYI   EL  +LK +   N K
Sbjct: 254 KEF-----IEGISQFSVKGDKESKLRF--AFKIYDMDKDGYISNGELFQVLKMMVGNNLK 412

Query: 234 EMNIQQLT 241
           +  +QQ+ 
Sbjct: 413 DTQLQQIV 436
>14945
          Length = 1337

 Score = 37.7 bits (86), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 33/127 (25%), Positives = 55/127 (43%), Gaps = 3/127 (2%)
 Frame = +1

Query: 2   AGPQQQPPYLHLAELTASQFLEIWKHFDADGNGYIEGKELENFFQELEKARKGSGMMSKS 61
            G ++  P   L E    +  E +  FDADG+G I+ KEL+   + L       G   K 
Sbjct: 61  GGRKKTGPKCELTEEQKQEIREAFDLFDADGSGTIDAKELKVAMRAL-------GFEPKK 219

Query: 62  DNFGEKMKEFMQKYDKNSDGKIEMAELAQILPTEENFLLCFRQHVG---SSAEFMEAWRK 118
               E++K+ + + DK   G I+            +FL    Q +    +  E ++A+R 
Sbjct: 220 ----EEIKKMIAEIDKEGTGTIDF----------NDFLTIMTQKMSEKDAKEEILKAFRL 357

Query: 119 YDTDRSG 125
           +D D +G
Sbjct: 358 FDDDETG 378

 Score = 28.9 bits (63), Expect = 2.4,   Method: Compositional matrix adjust.
 Identities = 15/39 (38%), Positives = 22/39 (56%), Gaps = 1/39 (2%)
 Frame = +1

Query: 198 EEFNAIFTFYDKDGSGYIDENELDALLKDL-YEKNKKEM 235
           +E    F  +D DGSG ID  EL   ++ L +E  K+E+
Sbjct: 112 QEIREAFDLFDADGSGTIDAKELKVAMRALGFEPKKEEI 228

 Score = 27.7 bits (60), Expect = 5.2,   Method: Compositional matrix adjust.
 Identities = 20/74 (27%), Positives = 35/74 (47%), Gaps = 1/74 (1%)
 Frame = +1

Query: 162 MFDLNGDGKLGLSEMSRLLPVQENFLLKFQGMKLTSEEFNAIFTFYDKDGSGYIDENE-L 220
           +FD +G G +   E+           ++  G +   EE   +    DK+G+G ID N+ L
Sbjct: 136 LFDADGSGTIDAKEL--------KVAMRALGFEPKKEEIKKMIAEIDKEGTGTIDFNDFL 291

Query: 221 DALLKDLYEKNKKE 234
             + + + EK+ KE
Sbjct: 292 TIMTQKMSEKDAKE 333
>22063
          Length = 688

 Score = 36.6 bits (83), Expect = 0.012,   Method: Compositional matrix adjust.
 Identities = 31/124 (25%), Positives = 55/124 (44%)
 Frame = +3

Query: 2   AGPQQQPPYLHLAELTASQFLEIWKHFDADGNGYIEGKELENFFQELEKARKGSGMMSKS 61
            G ++  P   L E    +  E +  FDADG+G I+ KEL+   + L       G   K 
Sbjct: 120 GGRKKTGPKCELTEEQKQEIREAFDLFDADGSGTIDAKELKVAMRAL-------GFEPKK 278

Query: 62  DNFGEKMKEFMQKYDKNSDGKIEMAELAQILPTEENFLLCFRQHVGSSAEFMEAWRKYDT 121
               E++K+ + + DK   G I+  +   I+  + +          +  E ++A+R +D 
Sbjct: 279 ----EEIKKMIAEIDKEGTGTIDFNDFLTIMTQKMS-------EKDAKEEILKAFRLFDD 425

Query: 122 DRSG 125
           D +G
Sbjct: 426 DETG 437

 Score = 34.3 bits (77), Expect = 0.060,   Method: Compositional matrix adjust.
 Identities = 33/121 (27%), Positives = 50/121 (41%), Gaps = 7/121 (5%)
 Frame = +3

Query: 121 TDRSGYIEANELKGFLSDLLKKANRPYDEPKLQ---EYTQTILRMFDL---NGDGKLGLS 174
           TDR  +   N +  F    L    R    PK +   E  Q I   FDL   +G G +   
Sbjct: 54  TDRRDHQPHNNMSNFKKTTLAGGGRKKTGPKCELTEEQKQEIREAFDLFDADGSGTIDAK 233

Query: 175 EMSRLLPVQENFLLKFQGMKLTSEEFNAIFTFYDKDGSGYIDENE-LDALLKDLYEKNKK 233
           E+           ++  G +   EE   +    DK+G+G ID N+ L  + + + EK+ K
Sbjct: 234 ELK--------VAMRALGFEPKKEEIKKMIAEIDKEGTGTIDFNDFLTIMTQKMSEKDAK 389

Query: 234 E 234
           E
Sbjct: 390 E 392
>00167
          Length = 2176

 Score = 35.0 bits (79), Expect = 0.028,   Method: Compositional matrix adjust.
 Identities = 22/61 (36%), Positives = 33/61 (54%)
 Frame = +3

Query: 160 LRMFDLNGDGKLGLSEMSRLLPVQENFLLKFQGMKLTSEEFNAIFTFYDKDGSGYIDENE 219
            R+ D N D KL + E   ++  +E  +      K+TSEE N +F  +DKDG+G +D  E
Sbjct: 747 FRIMDDNRDRKLSVDEF--IVGCRECRI-----AKMTSEELNEVFRRFDKDGTGTLDFEE 905

Query: 220 L 220
            
Sbjct: 906 F 908
>05237
          Length = 472

 Score = 34.7 bits (78), Expect = 0.038,   Method: Compositional matrix adjust.
 Identities = 27/109 (24%), Positives = 48/109 (44%), Gaps = 7/109 (6%)
 Frame = +3

Query: 17  TASQFLEIWKHFDADGNGYIEGKELENFFQELEKARKGSGMMSKSDNFGEKMK-----EF 71
           T  +  E ++ FD DGNG+I   EL +                   N GEK+      E 
Sbjct: 21  TDDELREAFRVFDKDGNGFISASELRHVMT----------------NLGEKLTDEEVDEM 152

Query: 72  MQKYDKNSDGKIEMAELAQILPTE--ENFLLCFRQHVGSSAEFMEAWRK 118
           +++ D + DG++   E  +++ T+  + FL         S+ F++ WR+
Sbjct: 153 IREADIDGDGQVNYEEFVKMMTTK*SKTFLQTIIAMCLHSS-FIKGWRQ 296

 Score = 30.8 bits (68), Expect = 0.59,   Method: Compositional matrix adjust.
 Identities = 14/35 (40%), Positives = 22/35 (62%)
 Frame = +3

Query: 196 TSEEFNAIFTFYDKDGSGYIDENELDALLKDLYEK 230
           T +E    F  +DKDG+G+I  +EL  ++ +L EK
Sbjct: 21  TDDELREAFRVFDKDGNGFISASELRHVMTNLGEK 125

 Score = 28.5 bits (62), Expect = 2.9,   Method: Compositional matrix adjust.
 Identities = 18/56 (32%), Positives = 28/56 (50%)
 Frame = +3

Query: 160 LRMFDLNGDGKLGLSEMSRLLPVQENFLLKFQGMKLTSEEFNAIFTFYDKDGSGYI 215
            R+FD +G+G +  SE+  ++    N      G KLT EE + +    D DG G +
Sbjct: 45  FRVFDKDGNGFISASELRHVMT---NL-----GEKLTDEEVDEMIREADIDGDGQV 188
>32088
          Length = 1928

 Score = 34.7 bits (78), Expect = 0.044,   Method: Compositional matrix adjust.
 Identities = 24/89 (26%), Positives = 42/89 (47%), Gaps = 3/89 (3%)
 Frame = +1

Query: 12  HLAELTASQFLEIWKHFDA---DGNGYIEGKELENFFQELEKARKGSGMMSKSDNFGEKM 68
           H   L   Q  E+   FD+   D NG+I   EL++ F+ +       G+       G ++
Sbjct: 913 HTVALDEDQLTELRSVFDSIDDDNNGHISXGELDSAFRAV-------GLNIP----GYEL 1059

Query: 69  KEFMQKYDKNSDGKIEMAELAQILPTEEN 97
           +  M KYD + DG++ M E   +  +E++
Sbjct: 1060RTIMSKYDASGDGRLNMDEFRTLYASEKS 1146
>08380
          Length = 1236

 Score = 33.9 bits (76), Expect = 0.073,   Method: Compositional matrix adjust.
 Identities = 44/173 (25%), Positives = 71/173 (41%), Gaps = 16/173 (9%)
 Frame = -1

Query: 67  KMKEFMQKYDKNSDGKIEMAELAQILPT--EENFLLCFRQHVGSSAEFMEAWRKYDTDRS 124
           K+K+ + K D + DGK+ +AEL   +    EE+F         ++ E  E ++  D D +
Sbjct: 882 KLKDIVYKVDSDKDGKLSVAELEAWVKDKMEEHF-------SEATQENEEIFKHLDPDNN 724

Query: 125 GYIEANE-------LKGFLSDLLKKANRPYDEPKL-----QEYTQTILRMFDLNGDGKLG 172
           G +   E        KG+  D+  +    YDZ +L     +E  +   R  D +G+    
Sbjct: 723 GKVHWKEYYVHFLLAKGYKQDVASRHVVDYDZIQLDPDAKEEIIRYKFRWSDADGEP--- 553

Query: 173 LSEMSRLLPVQE--NFLLKFQGMKLTSEEFNAIFTFYDKDGSGYIDENELDAL 223
              M   L  +E  +F    Q  K  +   N I    D +G G + E E  AL
Sbjct: 552 ---MDNELTREEFMSFRHPEQSEKTLNNMVNGILGGIDTNGDGVVTEEEFSAL 403
>11425
          Length = 599

 Score = 32.0 bits (71), Expect = 0.27,   Method: Compositional matrix adjust.
 Identities = 17/52 (32%), Positives = 29/52 (55%)
 Frame = -2

Query: 88  LAQILPTEENFLLCFRQHVGSSAEFMEAWRKYDTDRSGYIEANELKGFLSDL 139
           L + LP  E   +   +  G+ A+FME ++ +D +  G+I A EL+  L+ L
Sbjct: 391 LEEFLPIYET--ISKEKDTGTFADFMEGFKTFDREGQGFISAAELRHLLTGL 242
>33397
          Length = 1723

 Score = 32.0 bits (71), Expect = 0.30,   Method: Compositional matrix adjust.
 Identities = 14/26 (53%), Positives = 18/26 (69%)
 Frame = +3

Query: 160 LRMFDLNGDGKLGLSEMSRLLPVQEN 185
            RMFD+NGDG+L L E +R+  V  N
Sbjct: 210 FRMFDINGDGELDLEEFNRVQGVIRN 287
>12214
          Length = 654

 Score = 31.6 bits (70), Expect = 0.38,   Method: Compositional matrix adjust.
 Identities = 21/67 (31%), Positives = 34/67 (50%), Gaps = 4/67 (5%)
 Frame = -3

Query: 111 EFMEAWR----KYDTDRSGYIEANELKGFLSDLLKKANRPYDEPKLQEYTQTILRMFDLN 166
           ++++ WR    +YD++RSG IE NEL+     +    +     P+   + QT+L  FD  
Sbjct: 574 QYIQQWRSTFERYDSNRSGSIEGNELQAAYQQMGFNVS-----PR---FVQTVLYKFDHF 419

Query: 167 GDGKLGL 173
           G   L L
Sbjct: 418 GRRSLTL 398
>14366
          Length = 499

 Score = 30.8 bits (68), Expect = 0.67,   Method: Compositional matrix adjust.
 Identities = 19/55 (34%), Positives = 29/55 (52%), Gaps = 2/55 (3%)
 Frame = -3

Query: 178 RLLPVQE--NFLLKFQGMKLTSEEFNAIFTFYDKDGSGYIDENELDALLKDLYEK 230
           R L +QE    + K++    TS+     F  +DK+G+G I+  EL  +L  L EK
Sbjct: 317 RTLTLQEVIAIVTKYEFAPETSDNLREAFRIFDKEGNGMINAAELRHVLTHLGEK 153

 Score = 26.9 bits (58), Expect = 8.6,   Method: Compositional matrix adjust.
 Identities = 17/77 (22%), Positives = 35/77 (45%)
 Frame = -3

Query: 150 PKLQEYTQTILRMFDLNGDGKLGLSEMSRLLPVQENFLLKFQGMKLTSEEFNAIFTFYDK 209
           P+  +  +   R+FD  G+G +  +E+  +L           G KL+ EE + +    D 
Sbjct: 263 PETSDNLREAFRIFDKEGNGMINAAELRHVLT--------HLGEKLSDEEVDEMIREADI 108

Query: 210 DGSGYIDENELDALLKD 226
            G G +  N+   ++++
Sbjct: 107 SGDGQVSYNDFVKVMEN 57
>03616
          Length = 2372

 Score = 30.4 bits (67), Expect = 0.71,   Method: Compositional matrix adjust.
 Identities = 15/67 (22%), Positives = 34/67 (50%)
 Frame = +2

Query: 114 EAWRKYDTDRSGYIEANELKGFLSDLLKKANRPYDEPKLQEYTQTILRMFDLNGDGKLGL 173
           E + +YD DR+GYI    ++    DL ++   P D+    +    +++   ++ +G++ L
Sbjct: 893 EMFLRYDRDRTGYISVENMR----DLCRRLQLPVDD----DVILALVQQCTMDQEGRISL 1048

Query: 174 SEMSRLL 180
            +  R +
Sbjct: 1049EDFRRFV 1069
>01491
          Length = 1707

 Score = 30.4 bits (67), Expect = 0.76,   Method: Compositional matrix adjust.
 Identities = 17/47 (36%), Positives = 26/47 (55%), Gaps = 1/47 (2%)
 Frame = +1

Query: 179 LLPVQE-NFLLKFQGMKLTSEEFNAIFTFYDKDGSGYIDENELDALL 224
           ++PV++  +LLK  G  LT +E   +    D DGSG +D  E   L+
Sbjct: 394 VIPVEDLRWLLKSLGDDLTEDEIEDMIVETDTDGSGTVDYEEFRTLM 534

 Score = 28.5 bits (62), Expect = 2.8,   Method: Compositional matrix adjust.
 Identities = 14/31 (45%), Positives = 17/31 (54%)
 Frame = +2

Query: 18  ASQFLEIWKHFDADGNGYIEGKELENFFQEL 48
           ASQ   +   FD  GNG +  KEL N F+ L
Sbjct: 134 ASQTFHL---FDKKGNGTVSTKELANVFKSL 217
>08108
          Length = 818

 Score = 30.0 bits (66), Expect = 1.0,   Method: Compositional matrix adjust.
 Identities = 23/106 (21%), Positives = 46/106 (43%), Gaps = 3/106 (2%)
 Frame = +2

Query: 75  YDKNSDGKIEMAELAQILPTEENFLLCFRQHVGSSAEFMEAWRKYDTDRSGYIEANELKG 134
           +D +  G I   EL + L  +   +        +  +  E  +KYD+D +G I+ +E + 
Sbjct: 152 FDTDGSGSISAGELGEALRAQGADI--------TDDQTAELIKKYDSDSNGDIDTDEFRK 307

Query: 135 FL---SDLLKKANRPYDEPKLQEYTQTILRMFDLNGDGKLGLSEMS 177
            +   SD+ + A               + +  D +GDG++  SE++
Sbjct: 308 LVEGESDVARLAQSAL-----------MFKSLDADGDGQITASEIT 412
>26610
          Length = 455

 Score = 29.6 bits (65), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 29/121 (23%), Positives = 51/121 (42%)
 Frame = +3

Query: 114 EAWRKYDTDRSGYIEANELKGFLSDLLKKANRPYDEPKLQEYTQTILRMFDLNGDGKLGL 173
           EA+  +DTD  G I A+E+          A R           + +L    +   GK+ +
Sbjct: 54  EAFELFDTDNDGKIAASEVG--------TAIRSLGHVVTDSDLRRLLSKAGIEPHGKVDM 209

Query: 174 SEMSRLLPVQENFLLKFQGMKLTSEEFNAIFTFYDKDGSGYIDENELDALLKDLYEKNKK 233
           +   +L+          QG+  T ++ +  F   DK+GSG++   EL  LL  + ++   
Sbjct: 210 NRFRQLVQ-------PLQGVNYT-KQLDEAFNTIDKEGSGFVMATELRHLLTHMGDRITD 365

Query: 234 E 234
           E
Sbjct: 366 E 368
>01019
          Length = 1705

 Score = 28.5 bits (62), Expect = 3.3,   Method: Compositional matrix adjust.
 Identities = 18/72 (25%), Positives = 30/72 (41%), Gaps = 5/72 (6%)
 Frame = +1

Query: 28  FDADGNGYIEGKELENFFQELEKARKGSGMMSKSDNFGEKMK-----EFMQKYDKNSDGK 82
           FD DGNG+I   EL +                   N GEK+      E +++ D + DG+
Sbjct: 46  FDKDGNGFISAAELRHVMT----------------NLGEKLTDEEVDEMIREADIDGDGQ 177

Query: 83  IEMAELAQILPT 94
           +   E   ++ +
Sbjct: 178 VNYEEFVTMMTS 213
>04067
          Length = 1920

 Score = 28.1 bits (61), Expect = 3.5,   Method: Compositional matrix adjust.
 Identities = 16/42 (38%), Positives = 24/42 (57%), Gaps = 1/42 (2%)
 Frame = -1

Query: 179  LLPVQE-NFLLKFQGMKLTSEEFNAIFTFYDKDGSGYIDENE 219
            ++PV++  +LLK  G  LT +E   +    D DGSG +D  E
Sbjct: 1896 VIPVEDLRWLLKSLGDDLTEDEIEDMILETDTDGSGTVDYEE 1771
>28531
          Length = 1113

 Score = 28.1 bits (61), Expect = 3.9,   Method: Compositional matrix adjust.
 Identities = 14/34 (41%), Positives = 20/34 (58%)
 Frame = -1

Query: 127 IEANELKGFLSDLLKKANRPYDEPKLQEYTQTIL 160
           +EAN+ KGFL  L K   + Y E + +  TQT +
Sbjct: 567 LEANDSKGFLGFLFKFQXKTYREREREHRTQTFV 466
>32241
          Length = 328

 Score = 28.1 bits (61), Expect = 3.9,   Method: Compositional matrix adjust.
 Identities = 19/58 (32%), Positives = 27/58 (46%)
 Frame = -2

Query: 107 GSSAEFMEAWRKYDTDRSGYIEANELKGFLSDLLKKANRPYDEPKLQEYTQTILRMFD 164
           G++      + + DT+RSG IEANE        L  A R        ++ QT+L  FD
Sbjct: 261 GTTCSSEGTFERIDTNRSGSIEANE--------LVTAYRQMGFNVSPQFVQTVLYKFD 112
>01773
          Length = 1950

 Score = 28.1 bits (61), Expect = 4.5,   Method: Compositional matrix adjust.
 Identities = 35/153 (22%), Positives = 56/153 (36%), Gaps = 27/153 (17%)
 Frame = +1

Query: 51  ARKGSGMMSKSDNFGEKMKEFMQKYDKNSDGKIEMAELAQILP----------------- 93
           A KG G    +D +    K+  ++ DKN+DG +E+ EL ++                   
Sbjct: 121 AAKGKGTGPNTDAY----KQLFKEADKNNDGYLEIKELRELFKRNGSSLSDSQIADTFVF 288

Query: 94  ----------TEENFLLCFRQHVGSSAEFMEAWRKYDTDRSGYIEANELKGFLSDLLKKA 143
                     T E F     Q V    +  E ++  D    GY++ +ELK  L +  +K 
Sbjct: 289 FDGPRGDKRITFEXFCKGLDQIVMFVQKLAELFKAKDKSGDGYLDRDELKALLDESGQKF 468

Query: 144 NRPYDEPKLQEYTQTILRMFDLNGDGKLGLSEM 176
                     +    IL+  D N D K+   E 
Sbjct: 469 T--------ADDVSAILKSADKNNDNKICFEEF 543

 Score = 26.9 bits (58), Expect = 8.6,   Method: Compositional matrix adjust.
 Identities = 12/22 (54%), Positives = 15/22 (68%)
 Frame = +1

Query: 203 IFTFYDKDGSGYIDENELDALL 224
           +F   DK G GY+D +EL ALL
Sbjct: 382 LFKAKDKSGDGYLDRDELKALL 447
>15966
          Length = 362

 Score = 27.3 bits (59), Expect = 7.3,   Method: Compositional matrix adjust.
 Identities = 12/22 (54%), Positives = 15/22 (68%)
 Frame = +2

Query: 203 IFTFYDKDGSGYIDENELDALL 224
           +F   DK G GY+D +EL ALL
Sbjct: 149 LFKAKDKSGDGYLDRDELKALL 214
>08051
          Length = 1007

 Score = 26.9 bits (58), Expect = 7.7,   Method: Compositional matrix adjust.
 Identities = 13/37 (35%), Positives = 23/37 (62%), Gaps = 1/37 (2%)
 Frame = +1

Query: 22  LEIW-KHFDADGNGYIEGKELENFFQELEKARKGSGM 57
           +E W +  D DG+G +   ELE F++E ++  +G G+
Sbjct: 490 IEYWFRCMDIDGDGALSMYELEYFYEEQQQRMEGIGI 600
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|84697031|ref|NP_001033799.1| tropomodulin 2 [Mus
musculus]
         (351 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

31609                                                                  44   8e-05
19107                                                                  35   0.039
14637                                                                  30   1.5  
15371                                                                  29   3.0  
04282                                                                  28   8.1  
>31609
          Length = 841

 Score = 44.3 bits (103), Expect = 8e-05,   Method: Compositional matrix adjust.
 Identities = 23/67 (34%), Positives = 38/67 (56%)
 Frame = +1

Query: 223 ETNTHVKKFSLAATRSNDPVALAFAEMLKVNKTLKSLNVESNFITGTGILALVEALREND 282
           + N  +K+  LA     DP  +A  EML  N TL  L++ SN +  +G++AL   ++ N+
Sbjct: 355 QGNLCLKRLLLANNGIGDPGCMAAGEMLANNSTLLELDIASNRVLDSGLVALANNIKHNE 534

Query: 283 TLTEIKI 289
           TL  +K+
Sbjct: 535 TLQTLKL 555
>19107
          Length = 936

 Score = 35.4 bits (80), Expect = 0.039,   Method: Compositional matrix adjust.
 Identities = 27/98 (27%), Positives = 50/98 (51%), Gaps = 2/98 (2%)
 Frame = -1

Query: 243 ALAFAEMLKVNKTLKSLNVESNFITGTGILALVEALRENDTLTEIKIDNQRQQLGTAVEM 302
           ++ FA MLKVN++L+ ++++   +   G   + E L  N TLT + +   R         
Sbjct: 753 SVHFANMLKVNQSLEEVHLQKYDMRDFGAFRMAENLMHNYTLTYLNLSCNRITRDGV--K 580

Query: 303 EIAQMLEENSRI--LKFGYQFTKQGPRTRVAAAITKNN 338
           E+A++L++N+ +  L  GY   +      +A A+T  N
Sbjct: 579 ELAKVLKQNTALQTLDLGYNRLEDDGAIHIAEALTTLN 466
>14637
          Length = 455

 Score = 30.0 bits (66), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 21/72 (29%), Positives = 35/72 (48%), Gaps = 4/72 (5%)
 Frame = -1

Query: 35  VLDDLDPESATLPAGFR---QKDQTQKAATGPFDREHLLMY-LEKEALEQKDREDFVPFT 90
            L  +   +A+ P  F    Q++   K + GP D  +L +Y L +E  +Q   + F+PF 
Sbjct: 305 ALSGIQQYTASFPNAFNNQMQQNAAAKQSEGP-DGSNLFIYHLPQEFGDQDLMQMFMPFG 129

Query: 91  GEKKGRVFIPKE 102
                +VFI K+
Sbjct: 128 NVISAKVFIDKQ 93
>15371
          Length = 383

 Score = 28.9 bits (63), Expect = 3.0,   Method: Compositional matrix adjust.
 Identities = 21/67 (31%), Positives = 34/67 (50%), Gaps = 7/67 (10%)
 Frame = -2

Query: 43  SATLPAGFRQKDQTQKAAT------GPFDREHLLMY-LEKEALEQKDREDFVPFTGEKKG 95
           +A+ P  F  + Q Q+A +      GP D  +L +Y L +E  +Q   + F+PF      
Sbjct: 244 AASFPNAFNPQAQMQQANSAGKHSEGP-DGANLFIYHLPQEFGDQDLMQMFMPFGNVVSA 68

Query: 96  RVFIPKE 102
           +VFI K+
Sbjct: 67  KVFIDKQ 47
>04282
          Length = 1407

 Score = 27.7 bits (60), Expect = 8.1,   Method: Compositional matrix adjust.
 Identities = 12/28 (42%), Positives = 19/28 (67%)
 Frame = +2

Query: 307 MLEENSRILKFGYQFTKQGPRTRVAAAI 334
           ++ ENS   KFGY+ +K GPRT + + +
Sbjct: 698 LISENSVKRKFGYKESKFGPRTLLISGL 781
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|145207948|ref|NP_033572.2| tripartite motif protein
25 [Mus musculus]
         (634 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

20109                                                                  45   1e-04
14417                                                                  41   0.001
33436                                                                  40   0.002
07490                                                                  40   0.003
29117                                                                  40   0.004
10203                                                                  36   0.059
27368                                                                  35   0.094
11216                                                                  34   0.15 
21365                                                                  33   0.30 
14716                                                                  33   0.51 
07854                                                                  32   0.78 
27237                                                                  32   0.95 
22643                                                                  30   2.7  
04180                                                                  29   4.7  
01467                                                                  29   5.5  
15060                                                                  28   7.8  
33428                                                                  28   8.3  
23802                                                                  28   8.8  
>20109
          Length = 418

 Score = 44.7 bits (104), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 20/51 (39%), Positives = 28/51 (54%), Gaps = 1/51 (1%)
 Frame = -1

Query: 5   NPLAEELSCSVCLELFKEPVTTPCGHNFCMSCL-DETWVVQGPPYRCPQCR 54
           N   E ++C+VC E+F++P   PC H FC+ CL D         + CP CR
Sbjct: 355 NASKERVTCTVCFEVFRDPRFLPCHHTFCLQCLADLASRSPSSTFPCPVCR 203
>14417
          Length = 1383

 Score = 41.2 bits (95), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 16/33 (48%), Positives = 23/33 (69%)
 Frame = +2

Query: 27  PCGHNFCMSCLDETWVVQGPPYRCPQCRKVYQV 59
           PCGH FC SCLD   ++  P  RCP+C+++Y +
Sbjct: 542 PCGHRFCASCLDRA-MINNP--RCPKCQRLYGI 631
>33436
          Length = 583

 Score = 40.0 bits (92), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 20/52 (38%), Positives = 28/52 (53%)
 Frame = -1

Query: 7   LAEELSCSVCLELFKEPVTTPCGHNFCMSCLDETWVVQGPPYRCPQCRKVYQ 58
           + + L CS+CLEL   PV T C H FC  C+ E ++ +     CP C+  Y 
Sbjct: 418 MQKNLECSICLELMTSPVATKCEHYFCRFCITE-FLEKKRSVPCPLCKATYN 266
>07490
          Length = 1665

 Score = 40.0 bits (92), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 82/358 (22%), Positives = 133/358 (37%), Gaps = 42/358 (11%)
 Frame = -2

Query: 20   FKEPVTTPCGHNFCMSCLDETWVVQGPPYRCPQCRKVYQVRPQLQKNTVMCAV------- 72
            F EP   PCGH+FC +CL      QG    CP CR +  + P    ++++  V       
Sbjct: 1661 FVEPKLLPCGHHFCKACLLRWVESQGWRAACPFCRALI-ISPTKCVDSLVDGVESLPTNH 1485

Query: 73   -VEQFLQAEQ-ARTPVDDWTPPARFSASSAATQVACDHCLTEI-AVKTCLVCMASFCQEH 129
             +E+ ++A Q  R+P                    C  C   + AV  C+ C A  C   
Sbjct: 1484 GLEELVKARQVVRSP------------------NVCSRCDGSVEAVSYCIQCEAKMC--- 1368

Query: 130  LRPHFDSPAFQD--------HPLQSPIRDLLRR--------KCTQH-NRLRELFCPEHGE 172
                   P  QD        HP+++ +R L           KC +H +R    +C  H  
Sbjct: 1367 -------PGCQDTHDQTTXGHPVEA-VRTLTEAKLAGKHVVKCEKHPDRPANYYCRSHQT 1212

Query: 173  CICHICLVEHKTCSPTTLSQASADLEYKLRNKLTIMHSHINGATKALE------DVRSKQ 226
              C  C  +  +C    L+ +      + R + T+     N A  A +        R  +
Sbjct: 1211 LACDQCAQDDHSCCSGYLAISKLGPLARSRLQETVDVMKQNAANLAYQIKLAKYSYRETE 1032

Query: 227  QCVQ---DSMKRKMEQLRQEYMEMKAVIDAAETSSLRKLKEEEKRVYGKFDTIYQVLVKK 283
            + +    D ++ ++E  RQ  ++    +  A T SL   K  +  +  +  T  Q LV  
Sbjct: 1031 RDINEAFDDLEDRLESQRQLLLDTLHEMKDASTGSLETHKITQAALI-QNATALQKLVFN 855

Query: 284  KSEMQKLKAEVELIMDKGDEFE------FLEKAAKLQGESTKPVYIPKIDLDHDLIMG 335
             SE     + V ++ D  +  E       L+ AAK    +     + +I  D D I G
Sbjct: 854  ASE----GSLVSMVPDIAERVEDLHSQCSLDHAAKTVSVTFNKKQMNRIKADIDKIGG 693
>29117
          Length = 320

 Score = 39.7 bits (91), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 23/54 (42%), Positives = 28/54 (51%), Gaps = 4/54 (7%)
 Frame = +1

Query: 11  LSCSVCLELFKEPVTTPCGHNFCMSC----LDETWVVQGPPYRCPQCRKVYQVR 60
           L+C +CL+LF EP   PC H FC  C    LD    +Q     CP C+K   VR
Sbjct: 70  LTCPLCLQLFTEPKILPCQHTFCSHCLRKYLDHNTFLQWQCV-CPLCKKTCIVR 228
>10203
          Length = 2103

 Score = 35.8 bits (81), Expect = 0.059,   Method: Compositional matrix adjust.
 Identities = 24/59 (40%), Positives = 30/59 (50%)
 Frame = -2

Query: 3    ELNPLAEELSCSVCLELFKEPVTTPCGHNFCMSCLDETWVVQGPPYRCPQCRKVYQVRP 61
            ELN  A+E  C++C E  +     PCGH F  SCL  +W+ Q     CP CR     RP
Sbjct: 1127 ELN--ADE--CAICWEGMEAARKLPCGHLFHNSCL-RSWLEQDT--SCPTCRMSLSERP 972
>27368
          Length = 394

 Score = 35.0 bits (79), Expect = 0.094,   Method: Compositional matrix adjust.
 Identities = 17/47 (36%), Positives = 26/47 (55%)
 Frame = +1

Query: 10 ELSCSVCLELFKEPVTTPCGHNFCMSCLDETWVVQGPPYRCPQCRKV 56
          +L C +C +   +P+ T CGH FC SCL     VQ     CP+ +++
Sbjct: 1  DLLCQLCHQPLVDPLETKCGHTFCTSCLKSHLAVQA---LCPEDKQI 132
>11216
          Length = 528

 Score = 34.3 bits (77), Expect = 0.15,   Method: Composition-based stats.
 Identities = 32/117 (27%), Positives = 50/117 (42%), Gaps = 9/117 (7%)
 Frame = -2

Query: 487 SDGLQHYRSHP-QRFTYCSQVLGLHCYKNGIHYWEV-----ELQKNNFCGVGICYGSMER 540
           ++ L  +  HP  + T C  + G + Y  G+H WE+     +   +   GVG     +  
Sbjct: 365 NEDLMTFHRHPVAQSTDC--IRGRYGYTRGLHVWEIVWSTRQRGTHAVVGVGTADAPLHC 192

Query: 541 QGPESRLGRNPNSWCVEWFNNKISAWH---NNVEKTLPSTKATRVGVLLNCDHGFVI 594
            G +S +G N  SW  +   NK+  +H   N    T PS        +LN D  FV+
Sbjct: 191 VGYQSLVGSNKESWGWDLGRNKL--YHDMKNQPGITYPS--------VLNSDENFVV 51
>21365
          Length = 486

 Score = 33.5 bits (75), Expect = 0.30,   Method: Composition-based stats.
 Identities = 29/121 (23%), Positives = 59/121 (48%), Gaps = 7/121 (5%)
 Frame = -3

Query: 506 VLGLHCYKNGIHYWEVELQK---NNFCGVGICYGSMERQGPESRLGRNPNSWCVEWFNNK 562
           V+G   +  G+HYWEV + +   +    +GIC   +++    + LG++  +W + + ++K
Sbjct: 352 VMGSVGFSKGVHYWEVVIDRYDSHTDPSIGICRFDVDKT---TMLGKDDKAWSM-YIDDK 185

Query: 563 ISAWHNNVEKTLPS----TKATRVGVLLNCDHGFVIFFAVTEKVHLMYKFKVDFTEALYP 618
            S + +  E T  +     + T +G+LL+ +   + +F + E  H    F  D     +P
Sbjct: 184 RSWFIHRDEHTNRTDGGIKRGTVIGLLLDLNQHTLSYF-INEVPHGPIAF-TDLHGVFFP 11

Query: 619 A 619
           A
Sbjct: 10  A 8
>14716
          Length = 481

 Score = 32.7 bits (73), Expect = 0.51,   Method: Compositional matrix adjust.
 Identities = 18/51 (35%), Positives = 25/51 (49%)
 Frame = +2

Query: 7   LAEELSCSVCLELFKEPVTTPCGHNFCMSCLDETWVVQGPPYRCPQCRKVY 57
           L   L CS+CL   +    T CGH FC  C+ + W  +     CP CR+ +
Sbjct: 134 LPPSLKCSLCLGPRRRTTLTVCGHLFCWDCIHQ-WCQEKA--ECPLCREQF 277
>07854
          Length = 1752

 Score = 32.0 bits (71), Expect = 0.78,   Method: Compositional matrix adjust.
 Identities = 17/51 (33%), Positives = 27/51 (52%), Gaps = 6/51 (11%)
 Frame = -1

Query: 10   ELSCSVCLEL------FKEPVTTPCGHNFCMSCLDETWVVQGPPYRCPQCR 54
            +++C VCL+        +E  +T CGH FC +C+ +    Q   + CP CR
Sbjct: 1023 KVTCPVCLDTDAQIRRNRELYSTMCGHIFCSACIKQAIDSQ---HACPTCR 880
>27237
          Length = 704

 Score = 31.6 bits (70), Expect = 0.95,   Method: Compositional matrix adjust.
 Identities = 26/86 (30%), Positives = 40/86 (46%), Gaps = 6/86 (6%)
 Frame = -1

Query: 164 ELFCPEHGECICHICLVE-HKTCSPT-----TLSQASADLEYKLRNKLTIMHSHINGATK 217
           +L+C  H   ICH+C    H+ CS          +A A+L+ K+ +KL+   S IN    
Sbjct: 398 QLYCTAHSVSICHLCAASVHRNCSEVRDIHGRAEEARAELK-KMADKLSAGESQINERIN 222

Query: 218 ALEDVRSKQQCVQDSMKRKMEQLRQE 243
            ++D   K       M++K E  R E
Sbjct: 221 KIDDSLQK-------MEKKGEASRTE 165
>22643
          Length = 372

 Score = 30.0 bits (66), Expect = 2.7,   Method: Composition-based stats.
 Identities = 16/44 (36%), Positives = 20/44 (45%), Gaps = 3/44 (6%)
 Frame = +3

Query: 174 ICH---ICLVEHKTCSPTTLSQASADLEYKLRNKLTIMHSHING 214
           +CH    C   H TC  T  S+ S D  Y+L N   I    +NG
Sbjct: 39  VCHRGRTCFDVHHTCCRTGSSKGSLDFRYRLGNSRQICKFQMNG 170
>04180
          Length = 1535

 Score = 29.3 bits (64), Expect = 4.7,   Method: Compositional matrix adjust.
 Identities = 23/62 (37%), Positives = 32/62 (51%), Gaps = 4/62 (6%)
 Frame = +3

Query: 2  AELNPLAE-ELSCSVCL-ELFKEPVTTP--CGHNFCMSCLDETWVVQGPPYRCPQCRKVY 57
          AEL+  AE + +CS+CL  +    V +P  C H FC+ CL   W        CP  RKV+
Sbjct: 24 AELSDGAEAKNACSICLYTMDGVDVGSPESCDHTFCLDCL-LVWARNN--NTCPYDRKVF 194

Query: 58 QV 59
           +
Sbjct: 195NI 200
>01467
          Length = 1335

 Score = 29.3 bits (64), Expect = 5.5,   Method: Compositional matrix adjust.
 Identities = 22/62 (35%), Positives = 28/62 (45%), Gaps = 3/62 (4%)
 Frame = -2

Query: 13   CSVCLELFKEPVTTPCGHNFCMSCLDETWVVQGPPY-RCPQCRKVY--QVRPQLQKNTVM 69
            C VCL+   E +  PCGH  C      T  V  PP   CP CR     +VR  +  N  +
Sbjct: 1016 CVVCLDRTSEVIFLPCGH-VC------TCPVCSPPLSECPMCRAPISQRVRLSIPVNV*L 858

Query: 70   CA 71
            C+
Sbjct: 857  CS 852
>15060
          Length = 935

 Score = 28.5 bits (62), Expect = 7.8,   Method: Compositional matrix adjust.
 Identities = 13/35 (37%), Positives = 21/35 (60%)
 Frame = -2

Query: 294 VELIMDKGDEFEFLEKAAKLQGESTKPVYIPKIDL 328
           VE ++DK  ++ F+E  A+LQ E T    +  +DL
Sbjct: 358 VEFLLDKNGQYYFIEVNARLQVEHTVTEQVTGVDL 254
>33428
          Length = 402

 Score = 28.5 bits (62), Expect = 8.3,   Method: Composition-based stats.
 Identities = 19/50 (38%), Positives = 24/50 (48%), Gaps = 2/50 (4%)
 Frame = +2

Query: 8  AEELSCSVCLELFKEPVTTPCGH-NFCMSCLDETWVVQGPPYR-CPQCRK 55
           E  +C +CL   +E VT  CGH + C  C       Q  P R CP CR+
Sbjct: 50 GEGETCVICLNNPREVVTLDCGHISMCTDC------AQMLPQRLCPVCRE 181
>23802
          Length = 1077

 Score = 28.5 bits (62), Expect = 8.8,   Method: Compositional matrix adjust.
 Identities = 16/44 (36%), Positives = 21/44 (47%), Gaps = 5/44 (11%)
 Frame = +1

Query: 163 RELFCPEHGECICHICLVEH-----KTCSPTTLSQASADLEYKL 201
           RE+FC   GEC+C +C+ E      K C P  L      +  KL
Sbjct: 742 REIFCVRGGECVC-VCMRESVCESKKMCYPNFLPGVYGRIVLKL 870
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|157838011|ref|NP_083357.2| hypothetical protein
LOC74741 isoform 1 [Mus musculus]
         (1016 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

36305                                                                  45   1e-04
29179                                                                  44   4e-04
16549                                                                  40   0.006
30040                                                                  39   0.014
29426                                                                  30   4.8  
>36305
          Length = 586

 Score = 45.4 bits (106), Expect = 1e-04,   Method: Composition-based stats.
 Identities = 28/83 (33%), Positives = 45/83 (54%)
 Frame = -1

Query: 25  TDAFVEVKFGNTTFKTDVYLKSLNPQWNSEWFKFEVDDEDLQDEPLQITVLDHDTYSAND 84
           +D +  V  G  TFKT V   ++ P+WN E F+F +D+ D Q   L++ + D D  + +D
Sbjct: 577 SDPYTVVTVGAQTFKTKVIDDTVEPRWN-EVFEFVIDERDGQ--ILKLNISDKDPGNKDD 407

Query: 85  AIGKVYIDIDPLLYSEAATVISG 107
            +G   +DI  +   E A  +SG
Sbjct: 406 PLGSTTMDISTIF--EKAMWMSG 344
>29179
          Length = 1113

 Score = 43.9 bits (102), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 35/122 (28%), Positives = 60/122 (49%), Gaps = 4/122 (3%)
 Frame = -3

Query: 5   LKVKIVAGRHLPVMDRASDLTDAFVEVKF---GNTTFKTDVYLKSLNPQWNSEWFKFE-V 60
           L ++I+    LP  D  +  +D +V++           T V  ++LNP WN E F FE  
Sbjct: 493 LTLRIIRAVDLPAKD-VTGTSDPYVKILLLPDKKHKLLTKVKKRNLNPHWN-ECFLFEGW 320

Query: 61  DDEDLQDEPLQITVLDHDTYSANDAIGKVYIDIDPLLYSEAATVISGWFPIYDTIHGIRG 120
               L ++ L + V+D+D +S +D IG+ Y+ ++ +  S++        P  DT  G  G
Sbjct: 319 PHNKLLEKTLYLQVIDYDRFSRDDPIGETYLPLNEIDLSQSPVSWKYLQPCKDT-RGKLG 143

Query: 121 EI 122
           E+
Sbjct: 142 EL 137
>16549
          Length = 607

 Score = 39.7 bits (91), Expect = 0.006,   Method: Composition-based stats.
 Identities = 24/92 (26%), Positives = 47/92 (51%), Gaps = 5/92 (5%)
 Frame = +2

Query: 14  HLPVMDRASDLTDAFVEVKF-----GNTTFKTDVYLKSLNPQWNSEWFKFEVDDEDLQDE 68
           H+  + R+++L   +V+          T  KT +   S++P +N E  ++ + + + +  
Sbjct: 26  HVRDLARSAELPSPYVKTYLLPDPEKQTKRKTKIVKHSVHPTFN-EVLQYRMKETETRHR 202

Query: 69  PLQITVLDHDTYSANDAIGKVYIDIDPLLYSE 100
            LQ+TV DHD    N+ +G VY+ +  L  S+
Sbjct: 203 TLQVTVWDHDMLKENNFLGAVYLRLRDLELSD 298
>30040
          Length = 652

 Score = 38.5 bits (88), Expect = 0.014,   Method: Composition-based stats.
 Identities = 21/49 (42%), Positives = 26/49 (53%)
 Frame = -3

Query: 39  KTDVYLKSLNPQWNSEWFKFEVDDEDLQDEPLQITVLDHDTYSANDAIG 87
           KT V   S+NP WN E   F V  E L    L+++VLDHD     D +G
Sbjct: 497 KTSVRRASINPVWN-EALAFNVPAEVLPKVTLEVSVLDHDLIGHGDVLG 354
>29426
          Length = 361

 Score = 30.0 bits (66), Expect = 4.8,   Method: Composition-based stats.
 Identities = 24/82 (29%), Positives = 33/82 (40%), Gaps = 3/82 (3%)
 Frame = -3

Query: 761 KLRSMTPCCLCHVNFTVSLPEDELIQVTVTAVAITFDKNQALQTTKPHVEKSLQRAST-- 818
           + RS  P CLCH  + VS+     + +T+     T  +      T     +SL RA T  
Sbjct: 287 QTRSTLPLCLCHKKWPVSVNSMTSLPLTILTPPCTLRRTSP---TNGRRCESLSRAVTRP 117

Query: 819 -DNEELLQFPLELCSDSLPPHP 839
                     +  C DSLPP P
Sbjct: 116 CSKR*RGSRTMSDCDDSLPPRP 51
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|19526968|ref|NP_598516.1| tubulin, gamma complex
associated protein 2 [Mus musculus]
         (905 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

32473                                                                  45   1e-04
06821                                                                  32   0.81 
06273                                                                  32   1.0  
28117                                                                  32   1.1  
01255                                                                  30   4.4  
>32473
          Length = 1077

 Score = 45.4 bits (106), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 28/96 (29%), Positives = 54/96 (56%), Gaps = 2/96 (2%)
 Frame = +2

Query: 683 RQRMLNFVQNIQYYMMFEVMEPTWHILEKNL-KSASNIDDVLGHHISFLDNCLKDCMLTN 741
           RQ ML+FV+ +Q YM  ++++ TW  L+++L  S  ++DD+   H  +L+  L  C+L N
Sbjct: 152 RQEMLHFVRVLQGYMGNQIIQVTWRELQQSLDHSVHSLDDLKRVHADYLNKALFRCLL-N 328

Query: 742 PELLKVFSKLMSV-CVMFTNCMQKFTQSMKLDSELG 776
            +   + SK+ ++ C++   C    + + + D   G
Sbjct: 329 KKAAPIMSKIQNIFCLILKFCAHLASATWEQDEGTG 436
>06821
          Length = 482

 Score = 32.3 bits (72), Expect = 0.81,   Method: Composition-based stats.
 Identities = 22/73 (30%), Positives = 38/73 (52%), Gaps = 6/73 (8%)
 Frame = -2

Query: 738 MLTNPELLKVFSKLMSVCVMFTNCM----QKFT--QSMKLDSELGRLTLDQGSVQGPPTE 791
           M  N +LL  FS+L     +FTNC      KFT  Q+   + E+ +L+    +++GPP  
Sbjct: 277 MSFN*KLLNNFSQLFKTFYLFTNCFLNSCPKFTNFQTFDQNDEIHKLSR---ALKGPPDN 107

Query: 792 TERIEDRPRKELT 804
           ++  +D    ++T
Sbjct: 106 SQTFKDCTDPDIT 68
>06273
          Length = 1677

 Score = 32.0 bits (71), Expect = 1.0,   Method: Compositional matrix adjust.
 Identities = 23/78 (29%), Positives = 35/78 (44%), Gaps = 1/78 (1%)
 Frame = -1

Query: 327 YIQPAMRTIDILASLATSVDKGECVGGSTLSLLHDRSFNYTGDSQAQELCLYLTKAASAP 386
           Y+  A+       SL +S  K   V    L  +  RSF+YT  S    L L L  + + P
Sbjct: 552 YLSAALTAYQPSRSLXSSTGKLXKVPNFCLKTIGQRSFSYTAPSVWNSLPLLLRNSPTLP 373

Query: 387 YFE-ILEKWIYRGIIHDP 403
            F+ IL+ +++R     P
Sbjct: 372 QFKRILKTYLFRQAFSTP 319
>28117
          Length = 355

 Score = 32.0 bits (71), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 17/65 (26%), Positives = 36/65 (55%)
 Frame = -2

Query: 478 TLKERAYVEQIEKAFNYASKVLLDFLMEEKELVAHLRSIKRYFLMDQGDFFVHFMDLTEE 537
           T    A+   I+K   + ++ L   +++E +L   LR +K +FL+ +G+ ++ F+D  + 
Sbjct: 195 TFSGSAFESLIDKIRLHVAEHLWVMVVQEADLKGELRVMKDFFLLGRGELYLAFIDQAQH 16

Query: 538 ELRKP 542
            L+ P
Sbjct: 15  LLKGP 1
>01255
          Length = 1407

 Score = 30.0 bits (66), Expect = 4.4,   Method: Compositional matrix adjust.
 Identities = 19/70 (27%), Positives = 31/70 (44%)
 Frame = -1

Query: 601 THADPTELTLSGLEAFSFDYMVKWPLSLIINRKALTRYQMLFRHMFYCKHVERQLCSVWI 660
           TH +PT    S  +   F  +  +  +  ++R     Y  L R +  C+   +Q C++ I
Sbjct: 672 THNEPTHFPHSHRQVKGFTCL--FFQA*RVDRTHSANYSALVRFLLKCEKYXKQTCTILI 499

Query: 661 SNKTAKQHAL 670
             KT K HA 
Sbjct: 498 DYKTNKNHAC 469
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|30794510|ref|NP_038529.1| crystallin, alpha A [Mus
musculus]
         (196 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

01700                                                                  42   1e-04
31854                                                                  27   5.9  
>01700
          Length = 1829

 Score = 42.4 bits (98), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 30/90 (33%), Positives = 48/90 (53%)
 Frame = +3

Query: 98  LDVKHFSPEDLTVKVLEDFVEIHGKHNERQDDHGYISREFHRRYRLPSNVDQSALSCSLS 157
           ++V HF P+DLTV++ +D + I     +   +    +R   R + +P  VD    SC ++
Sbjct: 429 INVSHFHPDDLTVRLSDDRLIILESTLQSLTNMDCCTR-VSREFLIPEEVDMDTFSCKMN 605

Query: 158 ADGMLTFSGPKVQSGLDAGHSERAIPVSRE 187
           A+G L  S   V+S  DA  S R IP+ +E
Sbjct: 606 AEGHLIVSAA-VKS--DAA-SCRKIPIEQE 683
>31854
          Length = 718

 Score = 26.9 bits (58), Expect = 5.9,   Method: Compositional matrix adjust.
 Identities = 12/24 (50%), Positives = 14/24 (58%)
 Frame = -2

Query: 67  HMWFVMHQPHAGNPKNNPVKVRSD 90
           H  +V HQPH G+  N  V VR D
Sbjct: 450 HRRYVHHQPHLGHVWNGEVTVRED 379
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|94386112|ref|XP_358382.5| PREDICTED: Dmx-like 2 [Mus
musculus]
         (3268 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

13335                                                                  47   1e-04
19949                                                                  43   0.002
17266                                                                  40   0.011
30256                                                                  40   0.015
21105                                                                  40   0.017
02090                                                                  40   0.019
01249                                                                  39   0.029
00805                                                                  39   0.047
00825                                                                  37   0.15 
17598                                                                  36   0.29 
38177                                                                  35   0.38 
03387                                                                  35   0.61 
12806                                                                  35   0.61 
04672                                                                  35   0.68 
05261                                                                  34   0.84 
18981                                                                  34   0.86 
14500                                                                  34   1.0  
29912                                                                  34   1.1  
13278                                                                  33   1.3  
12960                                                                  33   1.7  
11493                                                                  33   2.2  
26939                                                                  33   2.5  
15337                                                                  33   2.6  
05046                                                                  32   2.8  
03156                                                                  32   4.7  
01327                                                                  32   4.9  
03748                                                                  32   5.9  
06521                                                                  31   8.1  
>13335
          Length = 863

 Score = 47.0 bits (110), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 18/65 (27%), Positives = 37/65 (56%)
 Frame = +1

Query: 3137 VLQYAPKQQLLISGGRKGYICIFDIRQRQLIHTFQAHDSAIKALALDSCEEYFTTGSAEG 3196
            V +++P    L+SG     IC++++  ++L+ ++  H+ ++ ALA      Y  +GS  G
Sbjct: 76   VCKFSPSSSHLVSGSDDDTICMWEVATQKLVRSYVGHEDSVMALAYSPNGHYLVSGSPNG 255

Query: 3197 NIKVW 3201
            ++ VW
Sbjct: 256  DLYVW 270

 Score = 38.5 bits (88), Expect = 0.050,   Method: Compositional matrix adjust.
 Identities = 29/127 (22%), Positives = 48/127 (37%), Gaps = 15/127 (11%)
 Frame = +1

Query: 3094 TSSSLVATSGHSNDNRNVCLWDTLISPGNSLIHGFTCHDHGATVLQYAPKQQLLISGGRK 3153
            +SS LV+ S    D+  +C+W+        L+  +  H+     L Y+P    L+SG   
Sbjct: 94   SSSHLVSGS----DDDTICMWEV---ATQKLVRSYVGHEDSVMALAYSPNGHYLVSGSPN 252

Query: 3154 GYICIFDI---RQRQLIHTFQAHDSAIKALAL------------DSCEEYFTTGSAEGNI 3198
            G + ++D      R L     AHD  +                  +C     TG  +  I
Sbjct: 253  GDLYVWDASFGHCRHLTLRVDAHDLGVTCCEFSPTFGTACAENSSTCNLLLATGGKDNLI 432

Query: 3199 KVWRLTG 3205
            K+W  + 
Sbjct: 433  KLWTFSA 453
>19949
          Length = 903

 Score = 42.7 bits (99), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 25/106 (23%), Positives = 46/106 (43%)
 Frame = +2

Query: 3110 NVCLWDTLISPGNSLIHGFTCHDHGATVLQYAPKQQLLISGGRKGYICIFDIRQRQLIHT 3169
            NV LWD         I+ +  H      L+++P  + + S    G + ++D+   +L+  
Sbjct: 62   NVKLWDIR---RKGCIYTYKGHTGCVCCLRFSPDGRWIASASEDGLVKLWDLTAGKLLTD 232

Query: 3170 FQAHDSAIKALALDSCEEYFTTGSAEGNIKVWRLTGHGLIHSFKSE 3215
             + H  A+  +     E    +GSA+  +K W L    LI + + E
Sbjct: 233  LKLHRDAVNTIEFHPHEFLLASGSADRTVKFWDLETFQLISTTEPE 370

 Score = 40.4 bits (93), Expect = 0.013,   Method: Compositional matrix adjust.
 Identities = 19/76 (25%), Positives = 35/76 (46%)
 Frame = +2

Query: 3138 LQYAPKQQLLISGGRKGYICIFDIRQRQLIHTFQAHDSAIKALALDSCEEYFTTGSAEGN 3197
            L + P      SG     + ++DIR++  I+T++ H   +  L       +  + S +G 
Sbjct: 11   LDFHPYGAYTASGSMDCNVKLWDIRRKGCIYTYKGHTGCVCCLRFSPDGRWIASASEDGL 190

Query: 3198 IKVWRLTGHGLIHSFK 3213
            +K+W LT   L+   K
Sbjct: 191  VKLWDLTAGKLLTDLK 238
>17266
          Length = 480

 Score = 40.4 bits (93), Expect = 0.011,   Method: Compositional matrix adjust.
 Identities = 28/110 (25%), Positives = 45/110 (40%)
 Frame = -1

Query: 3137 VLQYAPKQQLLISGGRKGYICIFDIRQRQLIHTFQAHDSAIKALALDSCEEYFTTGSAEG 3196
            VL  AP  +  +SG       ++D+R      TF  H+S I A+        F TGS + 
Sbjct: 444  VLSLAPDMRTFVSGACDASAKLWDVRDGMCKQTFSGHESDINAITYFPNGHAFATGSDDA 265

Query: 3197 NIKVWRLTGHGLIHSFKSEHAKQSIFRNIGAGVMQIAISQDNRLFSCGAD 3246
              +++ +     I  +  +        NI  G+  +A S+  RL   G D
Sbjct: 264  TCRLFDIRADQEIGMYSHD--------NIICGITSVAFSKSGRLLLGGYD 139
>30256
          Length = 961

 Score = 40.0 bits (92), Expect = 0.015,   Method: Composition-based stats.
 Identities = 35/138 (25%), Positives = 59/138 (42%)
 Frame = +3

Query: 3113 LWDTLISPGNSLIHGFTCHDHGATVLQYAPKQQLLISGGRKGYICIFDIRQRQLIHTFQA 3172
            +WD  I  G+ L +    H      +QY  K+  ++SG     + ++D      +HT Q 
Sbjct: 234  VWD--IESGHCL-NVLLGHMAAVRCVQYDGKR--VVSGAXDYTVRVWDPDTASCLHTLQG 398

Query: 3173 HDSAIKALALDSCEEYFTTGSAEGNIKVWRLTGHGLIHSFKSEHAKQSIFRNIGAGVMQI 3232
            H + + +L  D    Y  +GS + +I+VW +    L+H+     +  S            
Sbjct: 399  HTNRVYSLQFDGV--YVVSGSLDTSIRVWDVRCGKLVHTLMGHQSLTSGLE--------- 545

Query: 3233 AISQDNRLFSCGADGTLK 3250
               +DN L S  AD T+K
Sbjct: 546  --LKDNLLVSGNADSTVK 593

 Score = 39.7 bits (91), Expect = 0.019,   Method: Composition-based stats.
 Identities = 36/144 (25%), Positives = 63/144 (43%), Gaps = 4/144 (2%)
 Frame = +3

Query: 3111 VCLWDTLISPGNSLIHGFTCHDHGATVLQYAPKQQLLISGGRKGYICIFDIRQRQLIHTF 3170
            V +WD   +   S +H    H +    LQ+      ++SG     I ++D+R  +L+HT 
Sbjct: 348  VRVWDPDTA---SCLHTLQGHTNRVYSLQF--DGVYVVSGSLDTSIRVWDVRCGKLVHTL 512

Query: 3171 QAHDSAIKALALDSCEEYFTTGSAEGNIKVWRLTGHGLIHSFKSEHAKQSIFRNIGAGVM 3230
              H S    L L   +    +G+A+  +KVW +            H  + +   +G    
Sbjct: 513  MGHQSLTSGLELK--DNLLVSGNADSTVKVWDV------------HTGKCLQTLLGPNKH 650

Query: 3231 QIAIS--QDNRLF--SCGADGTLK 3250
            + A++  Q N+ F  +C  DGT+K
Sbjct: 651  RSAVTCLQFNKKFVVTCSDDGTVK 722
>21105
          Length = 650

 Score = 40.0 bits (92), Expect = 0.017,   Method: Compositional matrix adjust.
 Identities = 29/113 (25%), Positives = 46/113 (40%), Gaps = 1/113 (0%)
 Frame = +1

Query: 3142 PKQQLLISGGRKGYICIFDIRQRQLIHTFQAHDSAIKALALDSCEEYFTTGSAEGNIKVW 3201
            P   + I+     +I  FD    +LIH   AH  ++ +LA+D    Y  +GS + +I++W
Sbjct: 94   PTMPITITAHEDRHIRFFDNNTGKLIHAMVAHLDSVTSLAVDPNGLYLLSGSHDCSIRLW 273

Query: 3202 RLTGHGLIHSFKSEHAKQSIFRNIGAGVMQIAIS-QDNRLFSCGADGTLKTRV 3253
             L     +    S   K          +  +A   Q   + S GAD   K  V
Sbjct: 274  NLDSKTCVQEITSHRKK------FDESIHDVAFHPQKPYIASAGADALAKVFV 414
>02090
          Length = 1841

 Score = 39.7 bits (91), Expect = 0.019,   Method: Compositional matrix adjust.
 Identities = 37/142 (26%), Positives = 62/142 (43%), Gaps = 3/142 (2%)
 Frame = -3

Query: 3062 LSIWQVNQTASNPKPYMSWQCHSKATSDFAFITSSSLVATSGHSNDNRNVCLWDTLISPG 3121
            LSIW +    + P P +  +  S A + +A   S          +D  N+ +WD      
Sbjct: 1686 LSIWDL----ATPTPRIKAELTSSAPACYALAISPDGKVCFSCCSDG-NIAVWDL---HN 1531

Query: 3122 NSLIHGFTCHDHGATVLQYAPKQQLLISGGRKGYICIFDIRQ-RQLIHTFQAHDSAIKAL 3180
             +L+  F  H  GA+ +  +P    L +GG    +  +D+R+ RQL    Q HD + +  
Sbjct: 1530 QTLVRQFQGHTDGASCIDISPDGTKLWTGGLDNTVRSWDLREGRQL----QQHDFSSQIF 1363

Query: 3181 ALDSCE--EYFTTGSAEGNIKV 3200
            +L  C   E+   G    N++V
Sbjct: 1362 SLGYCPTGEWLAVGMESSNVEV 1297

 Score = 36.2 bits (82), Expect = 0.22,   Method: Compositional matrix adjust.
 Identities = 31/149 (20%), Positives = 58/149 (38%), Gaps = 3/149 (2%)
 Frame = -3

Query: 3058 GEGFLSIWQVNQTASNPKPYMSW-QCHSKATSDFAFITSSSLVATSGH--SNDNRNVCLW 3114
            G+G + +W ++Q  +   P ++W  C+   TS       SS   T       +   + +W
Sbjct: 1836 GKGCVKVWDISQPGTK-APCLNWIACNVTITSG-----PSSCCRTGAR*SWREASTLSIW 1675

Query: 3115 DTLISPGNSLIHGFTCHDHGATVLQYAPKQQLLISGGRKGYICIFDIRQRQLIHTFQAHD 3174
            D L +P   +    T        L  +P  ++  S    G I ++D+  + L+  FQ H 
Sbjct: 1674 D-LATPTPRIKAELTSSAPACYALAISPDGKVCFSCCSDGNIAVWDLHNQTLVRQFQGHT 1498

Query: 3175 SAIKALALDSCEEYFTTGSAEGNIKVWRL 3203
                 + +        TG  +  ++ W L
Sbjct: 1497 DGASCIDISPDGTKLWTGGLDNTVRSWDL 1411
>01249
          Length = 1743

 Score = 39.3 bits (90), Expect = 0.029,   Method: Compositional matrix adjust.
 Identities = 42/183 (22%), Positives = 70/183 (38%), Gaps = 21/183 (11%)
 Frame = -1

Query: 3042 TRLYFNSQGNKCGVADGEGFLSIWQ-------VNQTASNPKPYMSWQCHSKATSDFAFIT 3094
            T++ F   G++  VA   G L+IW         +Q A   KP  +   HS+  +    + 
Sbjct: 1359 TKIQFTDDGSQFVVATSSGHLNIWDFARVVTTTSQRARGLKPGRTINAHSEPITGL-HVG 1183

Query: 3095 SSSLVATSGHSNDNRNVCLWDTLISPGNSLIHGFTCHDHGATVLQYAPKQQLLISGGRKG 3154
                 A    S+ +    LWD L     +L+     ++ G   L    ++  L++G   G
Sbjct: 1182 CGGPAARVASSSSDGTCKLWDML---SGALLRTMV-YETGVGCLIMDKQEHFLLAGLDNG 1015

Query: 3155 YIC----IFDIRQRQLI---HT-------FQAHDSAIKALALDSCEEYFTTGSAEGNIKV 3200
             I        I Q ++    HT        Q H  A+  LA  S  +   +GS  G + +
Sbjct: 1014 DILCSPLFGQISQSEVFVSKHTTKAGERVLQGHSDAVTCLAFSSDGQRLASGSQNGKVII 835

Query: 3201 WRL 3203
            W +
Sbjct: 834  WNM 826
>00805
          Length = 3351

 Score = 38.5 bits (88), Expect = 0.047,   Method: Compositional matrix adjust.
 Identities = 21/80 (26%), Positives = 40/80 (50%), Gaps = 4/80 (5%)
 Frame = +1

Query: 1491 HSVKFGNVDADSPVE----ETIQDHSALKSSMLARKSIVEGAAIPDDVFCSPTVVQDGGL 1546
            H+ + GN + ++P++    + +   + LKSS    KS+  GA    +  CS  +VQ+G  
Sbjct: 271  HTFRHGN*NTENPLKLWA*KVMITQNMLKSSFSVPKSMQSGALYVHNSLCSNYIVQNGHF 450

Query: 1547 FEAAHALSPTLPQYHPTQLL 1566
             +  H  + ++  + P  LL
Sbjct: 451  VDCKHQSTSSVLDFFPLNLL 510
>00825
          Length = 1821

 Score = 37.0 bits (84), Expect = 0.15,   Method: Compositional matrix adjust.
 Identities = 30/122 (24%), Positives = 49/122 (40%), Gaps = 15/122 (12%)
 Frame = -2

Query: 3149 SGGRKGYICIFDIRQRQLIHTFQAHDSAIKALALDSCEEYFTTGSAEGNIKVWRLTGHG- 3207
            SG   G +  +++ ++Q+    QAHD  +  +A  S  +YF +  ++  IK W L   G 
Sbjct: 1820 SGACDGELICWNLPKQQMACRVQAHDGIVHGMAAHSSGQYFFSCGSDKTIKQWSLDPEGT 1641

Query: 3208 ------------LIHSFKSEHAKQSIFRNIGA--GVMQIAISQDNRLFSCGADGTLKTRV 3253
                         I++    H K  IF   G+   V     S+  R FS G +     + 
Sbjct: 1640 IAPEPVNTLLAKCIYTSLDHHWKDDIFVTSGSRVDVWDEKRSEPMRSFSWGVESVHHVKF 1461

Query: 3254 LP 3255
             P
Sbjct: 1460 NP 1455
>17598
          Length = 875

 Score = 35.8 bits (81), Expect = 0.29,   Method: Compositional matrix adjust.
 Identities = 32/147 (21%), Positives = 61/147 (41%), Gaps = 5/147 (3%)
 Frame = +1

Query: 3062 LSIWQVNQTASNPKPYMSWQCHSKATSDFAFITSSSLVATSGHSNDNRNVCLWDTL---- 3117
            L +W + +  +  + ++S   H++     AF   +  +A+ G    ++ + +W+T+    
Sbjct: 193  LRLWDIKK-GNTTRRFIS---HTRDALAVAFSPDNRQIASGGR---DKALKIWNTVGECK 351

Query: 3118 -ISPGNSLIHGFTCHDHGATVLQYAPKQQLLISGGRKGYICIFDIRQRQLIHTFQAHDSA 3176
                 NS     TC            K  L++S      I ++D +   L HTF  H + 
Sbjct: 352  FTVDANSHQDWVTC-----VKFHQDAKSPLVVSASMDKTIKVWDNQTMTLKHTFVGHKTQ 516

Query: 3177 IKALALDSCEEYFTTGSAEGNIKVWRL 3203
            I A+ L     Y  +GS +G +  W +
Sbjct: 517  INAIDLALKTYYLASGSKDGIVMTWNI 597

 Score = 32.0 bits (71), Expect = 3.9,   Method: Compositional matrix adjust.
 Identities = 27/118 (22%), Positives = 49/118 (41%), Gaps = 11/118 (9%)
 Frame = +1

Query: 3144 QQLLISGGRKGYICIFDIRQRQL----------IHTFQAHDSAIKALALDSCEEYFTTGS 3193
            ++ LI GGR   + ++D+  R+             T Q H   +  ++L +   Y  + S
Sbjct: 1    KEFLIXGGRDKLLIVWDLVPRKDGDEDETWGGPRRTLQGHSHFVSDVSLSADSRYVLSSS 180

Query: 3194 AEGNIKVWRLTGHGLIHSFKSEHAKQSIFRNIGAGVMQIAISQDNR-LFSCGADGTLK 3250
             +  +++W +        F S H + +         + +A S DNR + S G D  LK
Sbjct: 181  WDATLRLWDIKKGNTTRRFIS-HTRDA---------LAVAFSPDNRQIASGGRDKALK 324
>38177
          Length = 430

 Score = 35.4 bits (80), Expect = 0.38,   Method: Compositional matrix adjust.
 Identities = 15/65 (23%), Positives = 32/65 (49%)
 Frame = +3

Query: 3138 LQYAPKQQLLISGGRKGYICIFDIRQRQLIHTFQAHDSAIKALALDSCEEYFTTGSAEGN 3197
            L + P+ + L++G   G   +++          QAHD +++A+   + +++  T    G 
Sbjct: 6    LAWTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDVSVRAMRWSNHDQWMVTADHSGY 185

Query: 3198 IKVWR 3202
            IK W+
Sbjct: 186  IKYWQ 200
>03387
          Length = 1891

 Score = 34.7 bits (78), Expect = 0.61,   Method: Compositional matrix adjust.
 Identities = 40/155 (25%), Positives = 65/155 (41%), Gaps = 10/155 (6%)
 Frame = +1

Query: 3105 SNDNRNVCLWDTLISPGNSLIHG----FTCHDHGAT-VLQYAPKQQLLISGGRKGYICIF 3159
            ++D+  +CLWD   +   S +      FT H      V  +   + L  S      + I+
Sbjct: 418  ASDDHTICLWDINSTQRESRVVDAHTIFTGHTSVVEDVAWHLLHESLFGSVADDQKLMIW 597

Query: 3160 DIRQR---QLIHTFQAHDSAIKALALDSCEEY-FTTGSAEGNIKVWRLTGHGL-IHSFKS 3214
            D R     +  H   AH + +  L+ +   E+   TGSA+  + +W L    L +HSF+S
Sbjct: 598  DTRSNTTSKPSHVVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHSFES 777

Query: 3215 EHAKQSIFRNIGAGVMQIAISQDNRLFSCGADGTL 3249
               K  IF+      +Q +   +  L S G D  L
Sbjct: 778  H--KDEIFQ------VQWSPHNETILASSGTDRRL 858
>12806
          Length = 961

 Score = 34.7 bits (78), Expect = 0.61,   Method: Compositional matrix adjust.
 Identities = 35/133 (26%), Positives = 55/133 (41%), Gaps = 11/133 (8%)
 Frame = +3

Query: 3129 TCHDHGATVLQYAPKQQLLISGGRKGYICIFDIRQRQ----------LIHTFQAHDSAIK 3178
            T   +G  V+  A K   LISGGR   I ++D+  ++             T   H   I 
Sbjct: 3    TTMQYGEQVVDGATKP-FLISGGRDNNIIVWDL*PKKDGDEDQTWGVPRKTLTGHSHFIS 179

Query: 3179 ALALDSCEEYFTTGSAEGNIKVWRLTGHGLIHSFKSEHAKQSIFRNIGAGVMQIAISQDN 3238
             LAL +   +  + S +  +++W +           + +  S F N    V+ +A S DN
Sbjct: 180  DLALSADSRFALSSSWDATLRLWDI----------KKGSTTSRFINHTRDVLTVAFSPDN 329

Query: 3239 R-LFSCGADGTLK 3250
            R + S G D  LK
Sbjct: 330  RQIASGGRDKNLK 368
>04672
          Length = 470

 Score = 34.7 bits (78), Expect = 0.68,   Method: Compositional matrix adjust.
 Identities = 23/98 (23%), Positives = 43/98 (43%), Gaps = 4/98 (4%)
 Frame = -3

Query: 1474 ILVVGMDCEMHVYAQWKHSVKFGNVDADSPVE----ETIQDHSALKSSMLARKSIVEGAA 1529
            +L V   C+ H           GN + ++P++    + +  H+ LKSS   RK +  GA 
Sbjct: 441  VLSVSCVCDRH-----------GN*NTENPLKLWASKVVITHNMLKSSFSVRKHVQSGAF 295

Query: 1530 IPDDVFCSPTVVQDGGLFEAAHALSPTLPQYHPTQLLE 1567
               +  CS  +VQ+G   ++    S  +  + P +  +
Sbjct: 294  CMYNSLCSNYIVQNGHFLDSKCQSSSNVLGFFPLKFAD 181
>05261
          Length = 469

 Score = 34.3 bits (77), Expect = 0.84,   Method: Compositional matrix adjust.
 Identities = 20/79 (25%), Positives = 38/79 (48%), Gaps = 5/79 (6%)
 Frame = +1

Query: 1514 LKSSMLARKSIVEGAAIPDDVFCSPTVVQDGGLFEAAHALSPTLPQYHPTQL-----LEL 1568
            LKSS    +S+  GA    +  CS  +VQ+G   +  H  S ++  + P +      + +
Sbjct: 226  LKSSFSVPQSVQSGALCMYNYXCSNYIVQNGHFLDCKHQSSSSVLGFFPLKFADQLTIPI 405

Query: 1569 MDLGKVRRAKAILSHLVKC 1587
             ++G ++      +HL+KC
Sbjct: 406  PEVGLIKTVTKSETHLLKC 462
>18981
          Length = 407

 Score = 34.3 bits (77), Expect = 0.86,   Method: Composition-based stats.
 Identities = 18/64 (28%), Positives = 34/64 (53%), Gaps = 1/64 (1%)
 Frame = -2

Query: 3147 LISGGRKGYICIFDIRQRQLIHTFQAHDSAIKALALDSCEEYFTTGSAEGNIKVWRL-TG 3205
            ++SG     + ++++   + +H    H  AI A+  D  E    +GSA+G+++ W L TG
Sbjct: 259  VVSGSWDKTLIVWEVDTGRPVHQLHGHTEAITAVQFD--EGKAVSGSADGDVRTWALDTG 86

Query: 3206 HGLI 3209
              L+
Sbjct: 85   QCLL 74
>14500
          Length = 1238

 Score = 33.9 bits (76), Expect = 1.0,   Method: Compositional matrix adjust.
 Identities = 17/52 (32%), Positives = 29/52 (55%), Gaps = 5/52 (9%)
 Frame = +2

Query: 3138 LQYAPKQQLLISGGRKGYICIFDIR-----QRQLIHTFQAHDSAIKALALDS 3184
            L+++P  + L SG     +C++  +       Q +HTF  H +A+KALA+ S
Sbjct: 77   LRWSPDGKYLASGANDNLLCVWPAQVTGGNSTQPLHTFSQHQAAVKALAVVS 232
>29912
          Length = 510

 Score = 33.9 bits (76), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 32/141 (22%), Positives = 56/141 (39%), Gaps = 8/141 (5%)
 Frame = +3

Query: 3049 QGNKCGVADGEGFLSIWQVNQTASNPKPYMSWQCHSKATSDFA---FITSSSLVATSGHS 3105
            +GN   +    G + +W V Q     K   +   H+      +   FI SS   + + H 
Sbjct: 42   EGNYLALGTSTGEVQVWDVTQQ----KKLRTMAGHAARVGSLSWNSFIVSSGSRSGNIHH 209

Query: 3106 NDNRNVCLWDTLISPGNSLIHGFTCHDHGATVLQYAPKQQLLISGGRKGYICIFDIR--- 3162
            +D R            +  +   + H      L+++P  + L SG     +C++  +   
Sbjct: 210  HDVR----------VADHHVGTLSGHSQEVCGLRWSPDGKYLASGANDNLLCVWPAQVTG 359

Query: 3163 --QRQLIHTFQAHDSAIKALA 3181
                Q +HTF  H +A+KALA
Sbjct: 360  GNSTQPLHTFSQHQAAVKALA 422
>13278
          Length = 870

 Score = 33.5 bits (75), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 14/68 (20%), Positives = 33/68 (48%)
 Frame = +1

Query: 3146 LLISGGRKGYICIFDIRQRQLIHTFQAHDSAIKALALDSCEEYFTTGSAEGNIKVWRLTG 3205
            +L S      + ++++ +   +HT   H   + ++A     +Y  +GS +  + +W +  
Sbjct: 118  ILASASFDSTVRLWEVERGLCLHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNVQT 297

Query: 3206 HGLIHSFK 3213
              L+HS+K
Sbjct: 298  GSLVHSYK 321
>12960
          Length = 550

 Score = 33.1 bits (74), Expect = 1.7,   Method: Compositional matrix adjust.
 Identities = 24/128 (18%), Positives = 49/128 (38%), Gaps = 1/128 (0%)
 Frame = +2

Query: 3075 KPYMSWQCHSKATSDFAFITSSSLVATSGHSNDNRNVCLWDTLISPGNSL-IHGFTCHDH 3133
            +  ++  C  +A     F   S    T G    +++V LW+    P   L +  +  H H
Sbjct: 146  RKEVTINCKQQAVRAVRFSVDSRYCMTCG---SDKSVKLWN----PHRELFLKTYIGHGH 304

Query: 3134 GATVLQYAPKQQLLISGGRKGYICIFDIRQRQLIHTFQAHDSAIKALALDSCEEYFTTGS 3193
                 Q +     + SGG    + +FD+   Q +  ++ H   +  +  +       +GS
Sbjct: 305  EVLDAQGSGDNSQICSGGIDKTVVLFDVASGQALRKYRDHAGTVNCVKFNEESTVILSGS 484

Query: 3194 AEGNIKVW 3201
             +  ++ W
Sbjct: 485  LDNTVRAW 508
>11493
          Length = 535

 Score = 32.7 bits (73), Expect = 2.2,   Method: Compositional matrix adjust.
 Identities = 36/145 (24%), Positives = 63/145 (43%), Gaps = 6/145 (4%)
 Frame = -2

Query: 3113 LWDTLISPGN-SLIHGFTC--HDHGATVLQYAPKQQLLISGGRKGYICIFDIRQR--QLI 3167
            +WD +  PGN + +    C   D+    ++  P  + LI GG    + I+D+     ++ 
Sbjct: 402  VWD-ISQPGNKNPVSQLDCLQRDNYIRSVKLLPDGRTLIVGGEASNLSIWDLASPTPRIK 226

Query: 3168 HTFQAHDSAIKALALDSCEEYFTTGSAEGNIKVWRLTGHGLIHSFKSEHAKQSIFRNIGA 3227
                +   A  ALA+    +   +  ++GNI VW L    L+  F+              
Sbjct: 225  AELTSAAPACYALAISPDSKVCFSCCSDGNIAVWDLHNEILVRQFQGHT----------D 76

Query: 3228 GVMQIAISQD-NRLFSCGADGTLKT 3251
            G   I IS D +RL++ G D T+++
Sbjct: 75   GASCIDISPDGSRLWTGGLDNTVRS 1
>26939
          Length = 388

 Score = 32.7 bits (73), Expect = 2.5,   Method: Composition-based stats.
 Identities = 14/57 (24%), Positives = 27/57 (47%)
 Frame = +2

Query: 3145 QLLISGGRKGYICIFDIRQRQLIHTFQAHDSAIKALALDSCEEYFTTGSAEGNIKVW 3201
            + L+S      I ++D+R ++ + T  AH     ++       Y  +GS +  +KVW
Sbjct: 5    KYLVSASDDKTIRVWDLRNKRCMKTLYAHQHFCTSIDFHKAHPYVISGSVDQTVKVW 175
>15337
          Length = 860

 Score = 32.7 bits (73), Expect = 2.6,   Method: Compositional matrix adjust.
 Identities = 13/21 (61%), Positives = 16/21 (76%)
 Frame = -1

Query: 391 WSPDGEYFATAGKDDCLLKVW 411
           WSPDG+Y  T G+DD L+ VW
Sbjct: 179 WSPDGKYIVTGGEDD-LVTVW 120
>05046
          Length = 1992

 Score = 32.3 bits (72), Expect = 2.8,   Method: Compositional matrix adjust.
 Identities = 22/87 (25%), Positives = 40/87 (45%), Gaps = 6/87 (6%)
 Frame = +3

Query: 1477 VGMDCEMHVYAQWKHSV--KFGNVDADSPVE----ETIQDHSALKSSMLARKSIVEGAAI 1530
            + +D   H Y + +H    + GN + + P++    + I   + LKSS    K +  GA  
Sbjct: 567  IDLDHVRHSYLKVRH*CIHRHGN*NTEYPLKLWGSKVINPLNMLKSSFSVPKXVQSGALC 746

Query: 1531 PDDVFCSPTVVQDGGLFEAAHALSPTL 1557
             ++  CS   VQ+G   +  H  S ++
Sbjct: 747  MNNSLCSNYTVQNGHFLDCKHQSSSSV 827
>03156
          Length = 1014

 Score = 32.0 bits (71), Expect = 4.7,   Method: Compositional matrix adjust.
 Identities = 17/74 (22%), Positives = 31/74 (41%)
 Frame = +1

Query: 3128 FTCHDHGATVLQYAPKQQLLISGGRKGYICIFDIRQRQLIHTFQAHDSAIKALALDSCEE 3187
            +T HD   T + Y      + S  R   I ++       I  F  HD  + A+ L++   
Sbjct: 43   WTGHDREITKVCYGASCNGMFSASRDKTIKMWQRGNSHSIRDFIGHDMVVTAIHLNTDNT 222

Query: 3188 YFTTGSAEGNIKVW 3201
               +GS +  +++W
Sbjct: 223  LLCSGSRDNTVRIW 264
>01327
          Length = 2215

 Score = 31.6 bits (70), Expect = 4.9,   Method: Compositional matrix adjust.
 Identities = 17/74 (22%), Positives = 31/74 (41%)
 Frame = +3

Query: 3128 FTCHDHGATVLQYAPKQQLLISGGRKGYICIFDIRQRQLIHTFQAHDSAIKALALDSCEE 3187
            +T HD   T + Y      + S  R   I ++       I  F  HD  + A+ L++   
Sbjct: 153  WTGHDREITKVCYGASCNGMFSASRDKTIKMWQRGNSHSIRDFIGHDMVVTAIHLNTDNT 332

Query: 3188 YFTTGSAEGNIKVW 3201
               +GS +  +++W
Sbjct: 333  LLCSGSRDNTVRIW 374
>03748
          Length = 1657

 Score = 31.6 bits (70), Expect = 5.9,   Method: Compositional matrix adjust.
 Identities = 18/68 (26%), Positives = 32/68 (47%)
 Frame = -2

Query: 1504 VEETIQDHSALKSSMLARKSIVEGAAIPDDVFCSPTVVQDGGLFEAAHALSPTLPQYHPT 1563
            V + +   + LKSS    KS+  GA    +  CS  +VQ+G   E  H  S ++  + P 
Sbjct: 783  VSKVMTPLNMLKSSFSVPKSVQPGALCAYNSLCSNYIVQNGHFLECKHQSSSSVLGFFPL 604

Query: 1564 QLLELMDL 1571
            +  + + +
Sbjct: 603  KFADQLTI 580
>06521
          Length = 1872

 Score = 31.2 bits (69), Expect = 8.1,   Method: Composition-based stats.
 Identities = 21/83 (25%), Positives = 35/83 (42%), Gaps = 6/83 (7%)
 Frame = -2

Query: 544 THAELMPDKTATHEVHRHIS----HHANALCHFHIAASINPTTDIP--NVLVGTAFNIDD 597
           T A+ M +   TH   R  S    +HA  LCH H   +I  +  +P    L    +N+  
Sbjct: 767 TKAQAMNNLVWTHIYARSCSMSVPYHAQCLCHMHNVYAILSSMSVPYAQCLCHIMYNVSA 588

Query: 598 INGGFVVHWLNNKEFHFTSSTEI 620
           I+   + H ++N   H   +  +
Sbjct: 587 ISCKCLCHVVDNLAHHLVQAVHM 519
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|109627652|ref|NP_034018.2| complement component
factor H [Mus musculus]
         (1252 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

03995                                                                  45   2e-04
05037                                                                  40   0.009
27871                                                                  30   9.0  
>03995
          Length = 944

 Score = 45.1 bits (105), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 32/98 (32%), Positives = 40/98 (40%), Gaps = 3/98 (3%)
 Frame = -1

Query: 130 YTCDDGYQLLGEIDYRECGADG-WINDIPLCEVVKCLPVTELENGRIVSGAAETDQEYYF 188
           Y C  G+ L G   YR C ++G W    P C    C  +    NG  V  A+  D    F
Sbjct: 737 YRCRRGFTLTGPA-YRTCQSNGTWTGSEPTCTPKTCGKLHPPVNG-FVKPASCQDGAVPF 564

Query: 189 GQVVRFECNSGFKIEGHKEIHCSENGLWSNEKP--RCV 224
               +F CN GF+  G     C  N  WS +    RCV
Sbjct: 563 KTRCKFRCNKGFRRRGKPGAKCLANQRWSTDGSLTRCV 450

 Score = 35.0 bits (79), Expect = 0.20,   Method: Compositional matrix adjust.
 Identities = 25/89 (28%), Positives = 39/89 (43%), Gaps = 7/89 (7%)
 Frame = -1

Query: 979  TYHCSTGFGIDGPAFIICEG-GKWS-DPPKCIKTDCDVLPTVKNAIIRGKSKKS----YR 1032
            +Y C  GF + GPA+  C+  G W+   P C    C  L    N  ++  S +     ++
Sbjct: 740  SYRCRRGFTLTGPAYRTCQSNGTWTGSEPTCTPKTCGKLHPPVNGFVKPASCQDGAVPFK 561

Query: 1033 TGEQVTFRCQSPYQMNGSDTVTCV-NSRW 1060
            T  +  FRC   ++  G     C+ N RW
Sbjct: 560  T--RCKFRCNKGFRRRGKPGAKCLANQRW 480

 Score = 31.6 bits (70), Expect = 2.1,   Method: Compositional matrix adjust.
 Identities = 24/88 (27%), Positives = 35/88 (39%), Gaps = 9/88 (10%)
 Frame = -1

Query: 191 VVRFECNSGFKIEGHKEIHCSENGLWSNEKPRCVEILCT---PPRVENGDGINVKPVYKE 247
           V  + C  GF + G     C  NG W+  +P C    C    PP   NG    VKP   +
Sbjct: 746 VCSYRCRRGFTLTGPAYRTCQSNGTWTGSEPTCTPKTCGKLHPP--VNGF---VKPASCQ 582

Query: 248 N------ERYHYKCKHGYVPKERGDAVC 269
           +       R  ++C  G+  + +  A C
Sbjct: 581 DGAVPFKTRCKFRCNKGFRRRGKPGAKC 498
>05037
          Length = 723

 Score = 39.7 bits (91), Expect = 0.009,   Method: Compositional matrix adjust.
 Identities = 29/96 (30%), Positives = 38/96 (39%), Gaps = 3/96 (3%)
 Frame = -1

Query: 144 YRECGADG-WINDIPLCEVVKCLPVTELENGRIVSGAAETDQEYYFGQVVRFECNSGFKI 202
           YR C ++G W    P C    C  +    NG  V  A+  D    F    +F CN GF+ 
Sbjct: 708 YRTCQSNGTWTGSEPTCTPKTCGKLHPPVNG-FVKPASCQDGAVPFKTRCKFRCNKGFRR 532

Query: 203 EGHKEIHCSENGLWSNEKP--RCVEILCTPPRVENG 236
            G     C  N  WS +    RCV  + T    + G
Sbjct: 531 RGKPGAKCLANQRWSTDGSLTRCVPRVKTAKPAKQG 424
>27871
          Length = 427

 Score = 29.6 bits (65), Expect = 9.0,   Method: Compositional matrix adjust.
 Identities = 13/66 (19%), Positives = 27/66 (40%)
 Frame = -1

Query: 159 CEVVKCLPVTELENGRIVSGAAETDQEYYFGQVVRFECNSGFKIEGHKEIHCSENGLWSN 218
           C +  C+     +NG  +       + +     V + C+ G+ + G +   C + G W+ 
Sbjct: 361 CNITHCMDPGVPQNGLRIG------ESFLVASSVFYSCHQGYLLYGSRGRFCLDQGQWTG 200

Query: 219 EKPRCV 224
             P C+
Sbjct: 199 NLPSCL 182
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|110625938|ref|NP_082670.1| heat shock protein family
B (small), member 11 [Mus musculus]
         (143 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

32453                                                                  40   2e-04
05246                                                                  27   2.4  
>32453
          Length = 313

 Score = 40.4 bits (93), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 21/48 (43%), Positives = 29/48 (60%)
 Frame = -1

Query: 37  TFWTTTGMFPQEFIICFHKHVKIEKLVIQSYLVRTLRIEKTTSKEPLD 84
           TFW+TTG+FPQE +I F   + I  + I SY V  + +E  TS+   D
Sbjct: 139 TFWSTTGLFPQEVVIKFQALMTINSVEINSYNVCNIVLE--TSENEYD 2
>05246
          Length = 1801

 Score = 27.3 bits (59), Expect = 2.4,   Method: Composition-based stats.
 Identities = 13/33 (39%), Positives = 18/33 (54%)
 Frame = -3

Query: 111  YATFLRFIIVSAFDHFASVHSISAEGLTVSSLP 143
            +A F  F+I     +F   + I  +GLT SSLP
Sbjct: 1154 WAKFFVFVIFLTVFYFVVFYLIYCDGLTFSSLP 1056
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|21313478|ref|NP_079812.1| COMM domain containing 5
[Mus musculus]
         (224 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

13142                                                                  42   2e-04
04778                                                                  28   2.4  
>13142
          Length = 523

 Score = 42.0 bits (97), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 36/120 (30%), Positives = 59/120 (49%), Gaps = 8/120 (6%)
 Frame = -3

Query: 74  SANLSEERLAVLLAGTHTLLQQAL---RLPP---ASLKPDAFQDELQEL--GIPQDMIGD 125
           S N S+ +  VL  G+  +L+QA+      P    SL PD F   L++L   I  D + D
Sbjct: 365 SLNQSQAKTFVLSLGS--ILKQAVFQGSTDPHDIVSLFPDGFHKNLRDLIGKIIIDNMAD 192

Query: 126 LASLAFGSQRPLLDSVAQQQGSSLPRVSNFRWRVDVAISTSAQSRSLQPSVLMQLKLTDG 185
             S A G+              SLP++++F WRVDV  ++   +R   P+ ++ L++ +G
Sbjct: 191 WKSQAVGAH------------VSLPKLADFDWRVDVKTASDTVARMSVPTCILSLQVEEG 48
>04778
          Length = 1189

 Score = 28.5 bits (62), Expect = 2.4,   Method: Compositional matrix adjust.
 Identities = 22/74 (29%), Positives = 33/74 (44%)
 Frame = +3

Query: 44  DRSTFRKLLKLVVGALHGKDCREAVQHLGASANLSEERLAVLLAGTHTLLQQALRLPPAS 103
           D+   +K  K  +    G    +AVQH GA AN           GT T    A+   P+S
Sbjct: 132 DKERSKKTSKTPLETFLGATEEQAVQHAGAVAN-----------GTTT----AVSYNPSS 266

Query: 104 LKPDAFQDELQELG 117
           + P+ + + L +LG
Sbjct: 267 ITPEEYFNSLVDLG 308
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31543773|ref|NP_065237.3| C184L-22 [Mus musculus]
         (199 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

32508                                                                  42   2e-04
>32508
          Length = 1365

 Score = 41.6 bits (96), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 20/40 (50%), Positives = 31/40 (77%)
 Frame = +1

Query: 156 ALLQKLTWASVELGSSTSLETSIQLCGLIRACAEALGSLK 195
           AL++KL WA+ EL  +TS++ S+QLC LI+  ++AL S+K
Sbjct: 391 ALVEKLDWAAGELRGTTSVDYSLQLCQLIKVASDALSSVK 510
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|51770900|ref|XP_283496.3| PREDICTED: Dmx-like 1
isoform 1 [Mus musculus]
         (3013 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

19949                                                                  46   2e-04
13335                                                                  40   0.010
17598                                                                  40   0.019
21921                                                                  39   0.033
03387                                                                  39   0.044
38177                                                                  37   0.11 
10162                                                                  35   0.32 
13278                                                                  35   0.36 
02090                                                                  35   0.53 
12806                                                                  35   0.58 
19498                                                                  34   0.95 
17266                                                                  34   0.98 
02147                                                                  33   1.4  
22586                                                                  32   3.4  
21105                                                                  32   3.5  
27465                                                                  32   3.6  
05118                                                                  32   3.8  
19140                                                                  32   5.0  
30256                                                                  32   5.8  
>19949
          Length = 903

 Score = 46.2 bits (108), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 25/102 (24%), Positives = 41/102 (40%)
 Frame = +2

Query: 2850 NICLWDTLVAPANSLVHAFTCHDSGATVLAYAPKHQLLISGGRKGFTCIFDLXXXXXXXL 2909
            N+ LWD         ++ +  H      L ++P  + + S    G   ++DL        
Sbjct: 62   NVKLWDIR---RKGCIYTYKGHTGCVCCLRFSPDGRWIASASEDGLVKLWDLTAGKLLTD 232

Query: 2910 FQSHDSPVKAIAIDPTEEYFVTGSAEGNIKIWSLSSFSLLHT 2951
             + H   V  I   P E    +GSA+  +K W L +F L+ T
Sbjct: 233  LKLHRDAVNTIEFHPHEFLLASGSADRTVKFWDLETFQLIST 358
>13335
          Length = 863

 Score = 40.4 bits (93), Expect = 0.010,   Method: Compositional matrix adjust.
 Identities = 33/127 (25%), Positives = 50/127 (39%), Gaps = 15/127 (11%)
 Frame = +1

Query: 2834 SSSSLIATAGLSSDNRNICLWDTLVAPANSLVHAFTCHDSGATVLAYAPKHQLLISGGRK 2893
            SSS L++     SD+  IC+W+        LV ++  H+     LAY+P    L+SG   
Sbjct: 94   SSSHLVS----GSDDDTICMWEV---ATQKLVRSYVGHEDSVMALAYSPNGHYLVSGSPN 252

Query: 2894 GFTCIFDLXXXXXXXL---FQSHDSPVKAIAIDPT------------EEYFVTGSAEGNI 2938
            G   ++D        L     +HD  V      PT                 TG  +  I
Sbjct: 253  GDLYVWDASFGHCRHLTLRVDAHDLGVTCCEFSPTFGTACAENSSTCNLLLATGGKDNLI 432

Query: 2939 KIWSLSS 2945
            K+W+ S+
Sbjct: 433  KLWTFSA 453
>17598
          Length = 875

 Score = 39.7 bits (91), Expect = 0.019,   Method: Compositional matrix adjust.
 Identities = 35/128 (27%), Positives = 56/128 (43%), Gaps = 6/128 (4%)
 Frame = +1

Query: 2832 FVSSSSLIATAGL---SSDNRNICLWDTLVAPANSLVHAFTCHDSGATVLAYAPKHQLLI 2888
            FVS  SL A +     SS +  + LWD  +   N+    F  H   A  +A++P ++ + 
Sbjct: 127  FVSDVSLSADSRYVLSSSWDATLRLWD--IKKGNT-TRRFISHTRDALAVAFSPDNRQIA 297

Query: 2889 SGGRKGFTCIFDLXXXXXXXL-FQSHDSPVKAIAI--DPTEEYFVTGSAEGNIKIWSLSS 2945
            SGGR     I++        +   SH   V  +    D      V+ S +  IK+W   +
Sbjct: 298  SGGRDKALKIWNTVGECKFTVDANSHQDWVTCVKFHQDAKSPLVVSASMDKTIKVWDNQT 477

Query: 2946 FSLLHTFI 2953
             +L HTF+
Sbjct: 478  MTLKHTFV 501
>21921
          Length = 1341

 Score = 38.9 bits (89), Expect = 0.033,   Method: Compositional matrix adjust.
 Identities = 15/44 (34%), Positives = 27/44 (61%)
 Frame = -1

Query: 2909 LFQSHDSPVKAIAIDPTEEYFVTGSAEGNIKIWSLSSFSLLHTF 2952
            +++ H   V++I  DPT ++ V+GS +G I+ W +SS   + T 
Sbjct: 498  VYKGHTGIVRSICPDPTGQWLVSGSDDGTIRFWEVSSGRCMKTL 367
>03387
          Length = 1891

 Score = 38.5 bits (88), Expect = 0.044,   Method: Compositional matrix adjust.
 Identities = 36/129 (27%), Positives = 57/129 (44%), Gaps = 10/129 (7%)
 Frame = +1

Query: 2845 SSDNRNICLWDTLVAPANSLV----HAFTCHDSGATVLAYAPKHQ-LLISGGRKGFTCIF 2899
            +SD+  ICLWD       S V      FT H S    +A+   H+ L  S        I+
Sbjct: 418  ASDDHTICLWDINSTQRESRVVDAHTIFTGHTSVVEDVAWHLLHESLFGSVADDQKLMIW 597

Query: 2900 DLXXXXXXX---LFQSHDSPVKAIAIDPTEEYFV-TGSAEGNIKIWSLSSFSL-LHTFIN 2954
            D           +  +H + V  ++ +P  E+ + TGSA+  + +W L +  L LH+F  
Sbjct: 598  DTRSNTTSKPSHVVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHSF-- 771

Query: 2955 EHARQSIFR 2963
            E  +  IF+
Sbjct: 772  ESHKDEIFQ 798
>38177
          Length = 430

 Score = 37.4 bits (85), Expect = 0.11,   Method: Compositional matrix adjust.
 Identities = 17/64 (26%), Positives = 32/64 (50%)
 Frame = +3

Query: 2878 LAYAPKHQLLISGGRKGFTCIFDLXXXXXXXLFQSHDSPVKAIAIDPTEEYFVTGSAEGN 2937
            LA+ P+ + L++G   G   +++        + Q+HD  V+A+     +++ VT    G 
Sbjct: 6    LAWTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDVSVRAMRWSNHDQWMVTADHSGY 185

Query: 2938 IKIW 2941
            IK W
Sbjct: 186  IKYW 197
>10162
          Length = 1629

 Score = 35.4 bits (80), Expect = 0.32,   Method: Compositional matrix adjust.
 Identities = 19/79 (24%), Positives = 37/79 (46%), Gaps = 2/79 (2%)
 Frame = +3

Query: 2876 TVLAYAPKHQLLISGGRKGFTCIFDL--XXXXXXXLFQSHDSPVKAIAIDPTEEYFVTGS 2933
            T L +     +L++G + G   ++ +         + QSH  P     I P  +Y   G 
Sbjct: 39   TWLQWHGGAHVLLAGTQGGEVWLWQVPSQDYSKMKMLQSHGQPSLCGKILPNGKYVCVGY 218

Query: 2934 AEGNIKIWSLSSFSLLHTF 2952
            ++G +K+W L + + +HT+
Sbjct: 219  SDGVVKLWDLKTGTAVHTW 275

 Score = 32.0 bits (71), Expect = 3.9,   Method: Compositional matrix adjust.
 Identities = 18/75 (24%), Positives = 34/75 (45%), Gaps = 8/75 (10%)
 Frame = +3

Query: 2886 LLISGGRKGFTCIFDLXXXXXXXLF--------QSHDSPVKAIAIDPTEEYFVTGSAEGN 2937
            L++SG       +F++        F        Q  D+ V+++A  P   Y  T +  G+
Sbjct: 411  LIMSGCADATAKVFNVSSGKLXSAFNCAASQDSQDKDNSVESVAFCPVSPYAATATNSGS 590

Query: 2938 IKIWSLSSFSLLHTF 2952
            +++W L +    H+F
Sbjct: 591  VQVWDLPTSVARHSF 635
>13278
          Length = 870

 Score = 35.4 bits (80), Expect = 0.36,   Method: Compositional matrix adjust.
 Identities = 13/40 (32%), Positives = 25/40 (62%)
 Frame = +1

Query: 2913 HDSPVKAIAIDPTEEYFVTGSAEGNIKIWSLSSFSLLHTF 2952
            H  PV ++A  P  +Y  +GS +  + IW++ + SL+H++
Sbjct: 199  HQEPVYSVAFSPDGKYLASGSFDKCVHIWNVQTGSLVHSY 318
>02090
          Length = 1841

 Score = 34.7 bits (78), Expect = 0.53,   Method: Compositional matrix adjust.
 Identities = 22/91 (24%), Positives = 32/91 (35%)
 Frame = -3

Query: 2853 LWDTLVAPANSLVHAFTCHDSGATVLAYAPKHQLLISGGRKGFTCIFDLXXXXXXXLFQS 2912
            +WD L  P   +    T        LA +P  ++  S    G   ++DL        FQ 
Sbjct: 1680 IWD-LATPTPRIKAELTSSAPACYALAISPDGKVCFSCCSDGNIAVWDLHNQTLVRQFQG 1504

Query: 2913 HDSPVKAIAIDPTEEYFVTGSAEGNIKIWSL 2943
            H      I I P      TG  +  ++ W L
Sbjct: 1503 HTDGASCIDISPDGTKLWTGGLDNTVRSWDL 1411
>12806
          Length = 961

 Score = 34.7 bits (78), Expect = 0.58,   Method: Compositional matrix adjust.
 Identities = 31/135 (22%), Positives = 55/135 (40%), Gaps = 12/135 (8%)
 Frame = +3

Query: 2836 SSLIATAGLSSDNR---------NICLWDTLVAPANSLVHAFTCHDSGATVLAYAPKHQL 2886
            S  I+   LS+D+R          + LWD       S    F  H      +A++P ++ 
Sbjct: 165  SHFISDLALSADSRFALSSSWDATLRLWDI---KKGSTTSRFINHTRDVLTVAFSPDNRQ 335

Query: 2887 LISGGRKGFTCIFDLXXXXXXXL-FQSHDSPVKAIAI--DPTEEYFVTGSAEGNIKIWSL 2943
            + SGGR     I+++       +   +H   V  +    D      V+ S +  IK+W  
Sbjct: 336  IASGGRDKNLKIWNIMGECKYTVDANAHTDWVTCVRFHQDTKNPIVVSASNDKTIKVWDN 515

Query: 2944 SSFSLLHTFINEHAR 2958
             + +L +TF+   A+
Sbjct: 516  HTMTLKNTFVGHKAQ 560

 Score = 30.8 bits (68), Expect = 9.7,   Method: Compositional matrix adjust.
 Identities = 23/107 (21%), Positives = 40/107 (37%), Gaps = 11/107 (10%)
 Frame = +3

Query: 2848 NRNICLWD-----------TLVAPANSLVHAFTCHDSGATVLAYAPKHQLLISGGRKGFT 2896
            + NI +WD           T   P  +L    T H    + LA +   +  +S       
Sbjct: 72   DNNIIVWDL*PKKDGDEDQTWGVPRKTL----TGHSHFISDLALSADSRFALSSSWDATL 239

Query: 2897 CIFDLXXXXXXXLFQSHDSPVKAIAIDPTEEYFVTGSAEGNIKIWSL 2943
             ++D+        F +H   V  +A  P      +G  + N+KIW++
Sbjct: 240  RLWDIKKGSTTSRFINHTRDVLTVAFSPDNRQIASGGRDKNLKIWNI 380
>19498
          Length = 903

 Score = 33.9 bits (76), Expect = 0.95,   Method: Compositional matrix adjust.
 Identities = 25/109 (22%), Positives = 46/109 (42%), Gaps = 4/109 (3%)
 Frame = -1

Query: 2878 LAYAPKHQLLISGGRKGFTCIFD-LXXXXXXXLFQSHDSPVKAIAIDPTEEYFVTGSAEG 2936
            LA++P+   L S        +++ L       + + H   VK +  DP   Y  + S + 
Sbjct: 591  LAWSPQDLWLASCSVDNTIVVWNALKFSEQVAVIRGHAGMVKGVTWDPVGRYLASQSDDK 412

Query: 2937 NIKIWSLSSFSLLHTFINEHARQSIFRNIG--TGVMQIETGP-ANHIFS 2982
             +++W  S +        E   +S F+  G  T V+++   P  NH+ S
Sbjct: 411  TLRVWRTSDWK------EETCVKSCFKECGGTTHVLRLNWSPDGNHVVS 283
>17266
          Length = 480

 Score = 33.9 bits (76), Expect = 0.98,   Method: Composition-based stats.
 Identities = 17/69 (24%), Positives = 31/69 (44%)
 Frame = -1

Query: 2877 VLAYAPKHQLLISGGRKGFTCIFDLXXXXXXXLFQSHDSPVKAIAIDPTEEYFVTGSAEG 2936
            VL+ AP  +  +SG       ++D+        F  H+S + AI   P    F TGS + 
Sbjct: 444  VLSLAPDMRTFVSGACDASAKLWDVRDGMCKQTFSGHESDINAITYFPNGHAFATGSDDA 265

Query: 2937 NIKIWSLSS 2945
              +++ + +
Sbjct: 264  TCRLFDIRA 238
>02147
          Length = 1547

 Score = 33.5 bits (75), Expect = 1.4,   Method: Compositional matrix adjust.
 Identities = 13/26 (50%), Positives = 20/26 (76%)
 Frame = +2

Query: 169 VHLMKFSPDGEFFATAGKDDCLLKVW 194
           VH ++FSPDGE +A+ G +D  L++W
Sbjct: 803 VHCVRFSPDGELYAS-GSEDGTLRLW 877
>22586
          Length = 1352

 Score = 32.3 bits (72), Expect = 3.4,   Method: Compositional matrix adjust.
 Identities = 15/42 (35%), Positives = 24/42 (57%)
 Frame = +2

Query: 1081 ESTGGSCWILEQTIHLDELSTVLDSGISIDSNLVAYNKQETY 1122
            + T  +CW  +  +H    S +++SGIS+  N VAYN+   Y
Sbjct: 854  DRTKLTCWSQKNPLHD*NKSVIMNSGISVIKNHVAYNESTVY 979
>21105
          Length = 650

 Score = 32.0 bits (71), Expect = 3.5,   Method: Compositional matrix adjust.
 Identities = 21/83 (25%), Positives = 41/83 (49%), Gaps = 1/83 (1%)
 Frame = +1

Query: 2912 SHDSPVKAIAIDPTEEYFVTGSAEGNIKIWSLSSFSLLHTFINEHARQSIFRNIGTGVMQ 2971
            +H   V ++A+DP   Y ++GS + +I++W+L S + +   I  H ++         +  
Sbjct: 184  AHLDSVTSLAVDPNGLYLLSGSHDCSIRLWNLDSKTCVQE-ITSHRKK-----FDESIHD 345

Query: 2972 IETGPAN-HIFSCGADGTMKMRI 2993
            +   P   +I S GAD   K+ +
Sbjct: 346  VAFHPQKPYIASAGADALAKVFV 414
>27465
          Length = 658

 Score = 32.0 bits (71), Expect = 3.6,   Method: Compositional matrix adjust.
 Identities = 14/44 (31%), Positives = 24/44 (54%)
 Frame = -1

Query: 2909 LFQSHDSPVKAIAIDPTEEYFVTGSAEGNIKIWSLSSFSLLHTF 2952
            + ++H  P+  +A + +   F+TGS +   KIW  +S   LHT 
Sbjct: 376  VLRAHILPLTNVAFNKSGSSFITGSYDRTCKIWDTASAEELHTL 245
>05118
          Length = 2239

 Score = 32.0 bits (71), Expect = 3.8,   Method: Composition-based stats.
 Identities = 16/51 (31%), Positives = 30/51 (58%), Gaps = 1/51 (1%)
 Frame = +1

Query: 839 NLEKKRLGVDNILLDSDSSCNGFSEKFYLVVIECTEDNRSLLR-MWDLHLR 888
           ++EK  +   +I LD ++ CN F +K Y+ +I+C  +    ++  WDL +R
Sbjct: 508 HIEKYLIEFSHIFLDYENKCNIFFKK*YINLIKCKPEYTFQIK*AWDLAMR 660
>19140
          Length = 573

 Score = 31.6 bits (70), Expect = 5.0,   Method: Compositional matrix adjust.
 Identities = 13/43 (30%), Positives = 24/43 (55%)
 Frame = -3

Query: 2910 FQSHDSPVKAIAIDPTEEYFVTGSAEGNIKIWSLSSFSLLHTF 2952
             + H   VKA+ ++      ++GS++G I++WSL     + TF
Sbjct: 499  LKGHTDNVKALVLNRDGTQCLSGSSDGTIRLWSLGQQRCVATF 371
>30256
          Length = 961

 Score = 31.6 bits (70), Expect = 5.8,   Method: Composition-based stats.
 Identities = 41/221 (18%), Positives = 81/221 (36%), Gaps = 38/221 (17%)
 Frame = +3

Query: 2809 VTGSMPKPYLAWQCHNKTANDFVFVSSSSL----IATAGLSSDNRNICL--WDTLVAPAN 2862
            ++GS  +    W          ++  SS++    ++   + S +R+  L  WD     + 
Sbjct: 84   ISGSTDRSLKVWNADTGVCTHTLYGHSSTVRCLSLSGKKVVSGSRDATLRVWDI---ESG 254

Query: 2863 SLVHAFTCHDSGATVLAYAPKHQLLISGGRKGFTCIFDLXXXXXXXLFQSHDSPVKAIAI 2922
              ++    H +    + Y  K   ++SG       ++D          Q H + V ++  
Sbjct: 255  HCLNVLLGHMAAVRCVQYDGKR--VVSGAXDYTVRVWDPDTASCLHTLQGHTNRVYSLQF 428

Query: 2923 DPTEEYFVTGSAEGNIKIWSLSSFSLLHTFINEHARQSIFR------------------N 2964
            D    Y V+GS + +I++W +    L+HT +   +  S                     +
Sbjct: 429  DGV--YVVSGSLDTSIRVWDVRCGKLVHTLMGHQSLTSGLELKDNLLVSGNADSTVKVWD 602

Query: 2965 IGTG-VMQIETGPANH-------------IFSCGADGTMKM 2991
            + TG  +Q   GP  H             + +C  DGT+K+
Sbjct: 603  VHTGKCLQTLLGPNKHRSAVTCLQFNKKFVVTCSDDGTVKL 725
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6680776|ref|NP_031564.1| opsin 1 (cone pigments),
short-wave-sensitive (color blindness, tritan) [Mus musculus]
         (346 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

15134                                                                  43   2e-04
07708                                                                  41   6e-04
26971                                                                  37   0.008
09074                                                                  36   0.023
17845                                                                  35   0.040
15025                                                                  34   0.11 
26601                                                                  33   0.14 
38474                                                                  31   0.56 
00272                                                                  30   1.8  
31728                                                                  30   2.0  
26125                                                                  29   3.3  
10363                                                                  28   4.5  
24347                                                                  27   9.4  
>15134
          Length = 659

 Score = 42.7 bits (99), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 31/119 (26%), Positives = 62/119 (52%), Gaps = 12/119 (10%)
 Frame = -3

Query: 207 FIIPLSLICFSYSQL-LRTLRAVAAQQQESAT----TQKAEREVSHMVVVMVGSFCLCYV 261
           F++PL  I   Y+++ L+ +R    +Q++  +      K +R++  ++V +V  F +C+ 
Sbjct: 477 FVMPLLAIFVLYTKVCLKLIRLFKTEQEKLQSYPREIVKLKRQMVQIIVTVVMIFFICHT 298

Query: 262 PYAALAMY-MVNNR------NHGLDLRLVTIPAFFSKSSCVYNPIIYCFMNKQFRACIL 313
           PY AL ++ M  +R      N    L L+ +      S+   NP +Y F++++FR  +L
Sbjct: 297 PYRALVLWTMFEDRRTLAEINFESYLTLLYLTRILLYSNHAINPFVYNFVSRKFRRALL 121
>07708
          Length = 1263

 Score = 41.2 bits (95), Expect = 6e-04,   Method: Compositional matrix adjust.
 Identities = 52/240 (21%), Positives = 98/240 (40%)
 Frame = -2

Query: 38   FMGFVFFVGTPLNAIVLVATLHYKKLRQPLNYILVNVSLGGFLFCIFSVFTVFIASCHGY 97
             +G    VG   N +++ A + Y+ LR     +L +V++   L  + +V    I      
Sbjct: 1031 LLGLTAVVGLLGNLLMVRALVLYRNLRVDFFLLLGSVAVADILCLLIAVPRHIIDLTVTE 852

Query: 98   FLFGRHVCALEAFLGSVAGLVTGWSLAFLAFERYVVICKPFGSIRFNSKHALMVVLATWI 157
                   C    +L    G V  + L  LA  R +++    G+   +    ++  +  WI
Sbjct: 851  EPVTDAWCKTSKYLEVGTGFVAAYHLVVLAALRAILLTSR-GTNPPSPLQTVVCAVVVWI 675

Query: 158  IGIGVSIPPFFGWSRFIPEGLQCSCGPDWYTVGTKYRSEYYTWFLFIFCFIIPLSLICFS 217
            I +  +IP      +F  +GL C      Y   +    +   W +  F   +P  +I   
Sbjct: 674  IALLAAIPFLMIVGKF--DGL-CQ-----YRTHSLDEIKKDVWLVNSFSCFVPTFIIIIF 519

Query: 218  YSQLLRTLRAVAAQQQESATTQKAEREVSHMVVVMVGSFCLCYVPYAALAMYMVNNRNHG 277
            Y         V+ +  E + + K E+++S +V V+VG+F  C +P+  L +Y++   N  
Sbjct: 518  YV----LAHYVSKRYFEDSYSHK-EKQMSRLVSVIVGTFVFCQIPFRILDLYLLYKENEA 354
>26971
          Length = 467

 Score = 37.4 bits (85), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 21/64 (32%), Positives = 35/64 (54%), Gaps = 1/64 (1%)
 Frame = -1

Query: 121 WSLAFLAFERYVVICKPFGSIRFNS-KHALMVVLATWIIGIGVSIPPFFGWSRFIPEGLQ 179
           +SL  +A ER++ +  PF   R  +   AL+VV+ TW++ I + + P  GW+    EG  
Sbjct: 230 FSLLAVALERFLAVKHPFLYQRVMTINRALVVVVITWVLAIVIGLIPTMGWN-LGKEGFD 54

Query: 180 CSCG 183
            +C 
Sbjct: 53  NTCA 42
>09074
          Length = 465

 Score = 35.8 bits (81), Expect = 0.023,   Method: Compositional matrix adjust.
 Identities = 26/94 (27%), Positives = 40/94 (42%), Gaps = 7/94 (7%)
 Frame = -2

Query: 152 VLATWIIGIGVSIPPFFGWSRFIPEGLQCSCGPDWYTVGTKYRSEYYTWFLFIFCFIIPL 211
           VL   I  +  S+ PF GW  F  E    SC  +W T  +    + Y   +F F +++PL
Sbjct: 290 VLGALIYALCWSVCPFLGWGSFAQEPFGTSCSLNWVTKNSA--DKIYNVMVFAFIYLMPL 117

Query: 212 S-------LICFSYSQLLRTLRAVAAQQQESATT 238
                   L+    S L+  +  V     E+A+T
Sbjct: 116 GVMVGCSVLVLKRVSMLVSQVHPVVPAAPEAAST 15
>17845
          Length = 917

 Score = 35.0 bits (79), Expect = 0.040,   Method: Compositional matrix adjust.
 Identities = 30/118 (25%), Positives = 57/118 (48%), Gaps = 12/118 (10%)
 Frame = -2

Query: 204 IFCFIIPLSLICFSYSQLLRTLRAVAAQ-----QQESATTQKAEREVSHMVVVMVGSFCL 258
           I  +++P+ ++  +YS +  T R V  +         +  ++A+R+V  M+V ++  F +
Sbjct: 904 IVMYLLPVLVMIIAYSII--TYRLVTRKLPGFLNATISAQERAKRKVIKMLVAVLVCFVV 731

Query: 259 CYVPYAALAMYMVNNRNHGL------DLRLVTIPAFF-SKSSCVYNPIIYCFMNKQFR 309
           C+ P   L MY V     G+      D   +   A + +  +   NPI+YC  N++FR
Sbjct: 730 CWSPQQCLLMYGVFKPYLGVTVGEASDYHTIKYVALYVAYLNSALNPILYCGFNEKFR 557
>15025
          Length = 449

 Score = 33.9 bits (76), Expect = 0.11,   Method: Compositional matrix adjust.
 Identities = 23/74 (31%), Positives = 35/74 (47%)
 Frame = +1

Query: 242 EREVSHMVVVMVGSFCLCYVPYAALAMYMVNNRNHGLDLRLVTIPAFFSKSSCVYNPIIY 301
           ER V  ++  MV  F LC+ PYA ++         G+   +  IP   +KS    NPI Y
Sbjct: 49  ERSVKIILTTMV-VFMLCWTPYALMSFAASLGTEIGVGASV--IPTIMAKSHSAINPIAY 219

Query: 302 CFMNKQFRACILEM 315
               K++R  I ++
Sbjct: 220 FVCFKKYRLSIRQL 261
>26601
          Length = 397

 Score = 33.5 bits (75), Expect = 0.14,   Method: Compositional matrix adjust.
 Identities = 23/90 (25%), Positives = 46/90 (51%), Gaps = 1/90 (1%)
 Frame = -2

Query: 49  LNAIVLVATLHYKKLRQPLNYILVNVSLGGFLFCIFSV-FTVFIASCHGYFLFGRHVCAL 107
           +N+ V+ + +  +K    ++Y ++ +++      IF+  F +     HG+ +FG   C +
Sbjct: 273 MNSFVIWSFIVRRKTVVSVDYYILTLAISDLCSPIFAYPFAMVSTFSHGW-IFGETGCLV 97

Query: 108 EAFLGSVAGLVTGWSLAFLAFERYVVICKP 137
             FLG   G+V  + L+ L   RY+ +C P
Sbjct: 96  NGFLGFFFGIVDIFILSTLGITRYICVCHP 7
>38474
          Length = 550

 Score = 31.2 bits (69), Expect = 0.56,   Method: Compositional matrix adjust.
 Identities = 30/125 (24%), Positives = 59/125 (47%), Gaps = 11/125 (8%)
 Frame = +3

Query: 196 EYYTWFLFIFCFIIPLSLI--CFSY-SQLLRTLRAV-----AAQQQESATTQKAEREVSH 247
           +++T    +  +I+P ++I  C+S  S+ L+    V     A  ++      + ++  + 
Sbjct: 135 QFFTVTSLVLQYIVPCTIITFCYSMVSRALKKRSKVKIGSGARSREREEQEIRRKKRTNK 314

Query: 248 MVVVMVGSFCLCYVPY--AALAMYMVNNRNHGLDLRLV-TIPAFFSKSSCVYNPIIYCFM 304
           M++ MV  F  C++P   + L     ++  H     LV  I    + SS +YNP +Y +M
Sbjct: 315 MLIAMVIIFMCCWMPLNVSLLVREYQDSVEHWYYFTLVFFIAHVIAMSSTIYNPFLYAWM 494

Query: 305 NKQFR 309
           N  F+
Sbjct: 495 NDNFK 509
>00272
          Length = 2145

 Score = 29.6 bits (65), Expect = 1.8,   Method: Compositional matrix adjust.
 Identities = 30/89 (33%), Positives = 41/89 (46%), Gaps = 4/89 (4%)
 Frame = +3

Query: 12   NISSVGPWDGPQYHLAPVWAFRLQAA----FMGFVFFVGTPLNAIVLVATLHYKKLRQPL 67
            +IS+V PWDG      P+W+ RL+      F+   FF     N I L        + Q  
Sbjct: 1656 SISNV*PWDG------PLWSARLKTRFDLLFLM*TFFSQVEDNGIALY-------IMQSG 1796

Query: 68   NYILVNVSLGGFLFCIFSVFTVFIASCHG 96
            NY  V     G+ F +FS  ++FI SC G
Sbjct: 1797 NYPSV-----GWPF-LFSFTSIFITSCSG 1865
>31728
          Length = 774

 Score = 29.6 bits (65), Expect = 2.0,   Method: Compositional matrix adjust.
 Identities = 26/79 (32%), Positives = 36/79 (45%)
 Frame = -1

Query: 67  LNYILVNVSLGGFLFCIFSVFTVFIASCHGYFLFGRHVCALEAFLGSVAGLVTGWSLAFL 126
           L+Y+LV   LGGF  C+FS     + SC  Y  F  H+     F  S++ L TG    FL
Sbjct: 672 LHYLLVCFPLGGFT-CLFSN----VYSCALYIYFI*HLMNAYVFTXSLSDLNTGDY*KFL 508

Query: 127 AFERYVVICKPFGSIRFNS 145
            F + +  C     +  N 
Sbjct: 507 PFPQLIFNCPLVNCLHLNQ 451
>26125
          Length = 956

 Score = 28.9 bits (63), Expect = 3.3,   Method: Compositional matrix adjust.
 Identities = 11/25 (44%), Positives = 15/25 (60%)
 Frame = +2

Query: 297 NPIIYCFMNKQFRACILEMVCRKPM 321
           NPIIY F +  FR    E++C+ P 
Sbjct: 59  NPIIYAFRSPSFREGYKEILCQTPT 133
>10363
          Length = 1332

 Score = 28.5 bits (62), Expect = 4.5,   Method: Compositional matrix adjust.
 Identities = 10/24 (41%), Positives = 17/24 (70%)
 Frame = +2

Query: 256 FCLCYVPYAALAMYMVNNRNHGLD 279
           FCLC++   +L +++V+NR H  D
Sbjct: 797 FCLCFLSGVSLGLHLVDNRVHVCD 868
>24347
          Length = 1368

 Score = 27.3 bits (59), Expect = 9.4,   Method: Compositional matrix adjust.
 Identities = 9/17 (52%), Positives = 13/17 (76%)
 Frame = -3

Query: 190 GTKYRSEYYTWFLFIFC 206
             K RS++Y+WF F+FC
Sbjct: 214 AAK*RSDHYSWFFFLFC 164
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6755300|ref|NP_035384.1| retinol binding protein 1,
cellular [Mus musculus]
         (135 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

31753                                                                  41   2e-04
14358                                                                  39   9e-04
07957                                                                  33   0.042
>31753
          Length = 374

 Score = 40.8 bits (94), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 24/59 (40%), Positives = 32/59 (54%), Gaps = 5/59 (8%)
 Frame = -3

Query: 5   FNGYWKMLSNENFEEYLRALDVNVALR-KIANLLKPDKEIVQ----DGDHMIIRTLSTF 58
            NG WK++S +NFE YL A+ V    R K   LL P+  I+Q    DGD + I T +  
Sbjct: 219 LNGKWKLVSVDNFESYLDAVGVQGEFRDKALKLLTPENNILQDIAIDGDAISITTTTPI 43
>14358
          Length = 996

 Score = 38.5 bits (88), Expect = 9e-04,   Method: Compositional matrix adjust.
 Identities = 27/97 (27%), Positives = 49/97 (50%), Gaps = 6/97 (6%)
 Frame = +1

Query: 44  VQDGDHMIIRTLSTFRNYIMDFQVGKEFEEDLTGIDDRKCMTTVSWDGDKLQCVQ-KGEK 102
           VQD   ++IRT STF    + F++ +E+EE +     +K     +++  KL+      E 
Sbjct: 13  VQDDGKIVIRTNSTFMKSEVSFKLNEEYEE-INPHSKKKFXNMPTYENGKLRVTPTPAEP 189

Query: 103 EGRGWTQWIEGD-----ELHLEMRAEGVICKQVFKKV 134
               + ++ E +     E+ + ++ E V CK+ FKKV
Sbjct: 190 IDVPYPEYXEREITDDGEMLVTLKVEDVXCKRWFKKV 300
>07957
          Length = 883

 Score = 32.7 bits (73), Expect = 0.042,   Method: Compositional matrix adjust.
 Identities = 18/66 (27%), Positives = 35/66 (53%)
 Frame = +1

Query: 7   GYWKMLSNENFEEYLRALDVNVALRKIANLLKPDKEIVQDGDHMIIRTLSTFRNYIMDFQ 66
           G W+ +S EN +     + V  A+R+ A   K +  I +DG    + T++  ++ ++ F 
Sbjct: 277 GKWQSVSYENMDPLWDVMGVPDAMRQFARDKKTELTIEKDGGQWKLTTVAGDKSRVIVFP 456

Query: 67  VGKEFE 72
           VG+E +
Sbjct: 457 VGQEVD 474
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|83699400|ref|NP_033099.2| rod outer segment membrane
protein 1 [Mus musculus]
         (351 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

25023                                                                  43   2e-04
16993                                                                  31   0.89 
11991                                                                  30   1.1  
>25023
          Length = 893

 Score = 43.1 bits (100), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 20/59 (33%), Positives = 30/59 (50%)
 Frame = -3

Query: 128 SLNQGLEEGLEAALAHYKDTEVPGRCQAKRLMDELQLRYHCCGRHCYKDWFGVQWVSNR 186
            L +G +EGL +A+  Y      G  +     DELQ +  CCG + Y DWF  +W + +
Sbjct: 453 KLEKGFKEGLGSAIDRYDQ---KGEEEITAAFDELQQKLSCCGINSYSDWFSSEWAAKQ 286
>16993
          Length = 2290

 Score = 30.8 bits (68), Expect = 0.89,   Method: Compositional matrix adjust.
 Identities = 14/33 (42%), Positives = 18/33 (54%)
 Frame = -1

Query: 155  AKRLMDELQLRYHCCGRHCYKDWFGVQWVSNRY 187
             ++  D+LQ  + CCG H Y DW  V  VS  Y
Sbjct: 1819 CQKAWDKLQTEFSCCGAHNYTDWQNVT-VSTVY 1724
>11991
          Length = 881

 Score = 30.4 bits (67), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 11/21 (52%), Positives = 13/21 (61%)
 Frame = -2

Query: 160 DELQLRYHCCGRHCYKDWFGV 180
           D +Q  Y CCG   Y+DWF V
Sbjct: 499 DVIQKEYDCCGVDTYQDWFTV 437
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|94380110|ref|XP_001003324.1| PREDICTED: hypothetical
protein LOC74206 isoform 3 [Mus musculus]
         (1776 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

31328                                                                  45   2e-04
21918                                                                  31   4.9  
>31328
          Length = 418

 Score = 45.4 bits (106), Expect = 2e-04,   Method: Composition-based stats.
 Identities = 21/67 (31%), Positives = 38/67 (56%), Gaps = 2/67 (2%)
 Frame = +3

Query: 682 TYQD--YEIMFHVSTLLPYTPNNRQQLLRKRHIGNDIVTIIFQEPGALPFTPKNIRSHFQ 739
           T+QD   +++FH++TL+     +     +KRH+GND VTI++ + G   +    +   F 
Sbjct: 78  TWQDESMKVIFHIATLMRNRKQDHNLTFKKRHVGNDFVTIVYNDSGE-EYKLGTLMGQFN 254

Query: 740 HVFIIVR 746
            V I++R
Sbjct: 255 FVNIVIR 275
>21918
          Length = 462

 Score = 30.8 bits (68), Expect = 4.9,   Method: Composition-based stats.
 Identities = 16/38 (42%), Positives = 21/38 (55%), Gaps = 3/38 (7%)
 Frame = -3

Query: 732 KNIRSHFQHVFIIVRVHNPCTEN---VCYSMAVTRSKD 766
           K+I  H  HV I  R HN CT     VC+S+A+  S +
Sbjct: 298 KHINRHNIHV*IHTRTHNACTHTEI*VCHSVAIKLSHE 185
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|124517718|ref|NP_001028554.2| calcium channel,
voltage-dependent, alpha 2/delta subunit 4 [Mus musculus]
         (1144 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

19289                                                                  44   3e-04
38178                                                                  36   0.11 
25280                                                                  35   0.12 
10776                                                                  33   0.71 
04901                                                                  33   0.97 
02835                                                                  32   2.1  
17044                                                                  31   3.2  
09227                                                                  31   3.2  
11168                                                                  30   4.7  
06146                                                                  30   5.5  
>19289
          Length = 734

 Score = 44.3 bits (103), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 25/101 (24%), Positives = 47/101 (46%), Gaps = 8/101 (7%)
 Frame = +3

Query: 504 FTSEAQSLMLLTTVAMPVFSKKNETRSHGILLGVVGSDVTLRELMKLAPRYKLGVHGYAF 563
           +  EA   + L+ ++ P F      R    L+G+VG D+ + ++ +    Y    H YAF
Sbjct: 18  YIDEADGALTLS-ISQPCFHVPVSERERVQLMGMVGVDLHMEDIAQDITYYNNNDHSYAF 194

Query: 564 LNTNNGYILSHP--------DLRPLYREGKKLRPKPNYNSV 596
           L T +GY + HP          +P++ + +     P +++V
Sbjct: 195 LITTHGYTIQHPVFQRPLRTSFQPMHTDIRHFEQHPGFDTV 317
>38178
          Length = 772

 Score = 35.8 bits (81), Expect = 0.11,   Method: Composition-based stats.
 Identities = 30/110 (27%), Positives = 46/110 (41%), Gaps = 17/110 (15%)
 Frame = +1

Query: 237 LNPVFVENFQRDPTLTWQYFGSSTGFFRIYPG--IKWMPDENGVIA----------FDCR 284
           L  V+  N    P+L WQYF S  G    +P    +W+ D +               D R
Sbjct: 1   LTEVWRSNTHYFPSLKWQYFISVLGLHNEFPASSFRWLGDCHSPTGSRNRHSCHNIHDTR 180

Query: 285 NRGWYIQA-ATSPKDIVILVDISGSMKGLRM----AIAKHTITTILDTLG 329
           +R  ++       K +VI++D   SM   ++    AIAKH I +    +G
Sbjct: 181 HRDVFLSTIQPQRKHVVIMMDHGNSMSVTQLRTAKAIAKHLIASFPTMIG 330
>25280
          Length = 771

 Score = 35.4 bits (80), Expect = 0.12,   Method: Composition-based stats.
 Identities = 17/47 (36%), Positives = 21/47 (44%)
 Frame = +1

Query: 927 MKQLLSMGVFSRVTMYDYQAMCKPPDHHHSAAESLFSPLSAFLMVAR 973
           M  L    V S V +  +  +C PP H H+     FSPL   LM  R
Sbjct: 313 MISLTHKTVLSHVKLSCFSFLCHPPSHTHTHPSVCFSPLHICLMCVR 453
>10776
          Length = 1909

 Score = 33.1 bits (74), Expect = 0.71,   Method: Compositional matrix adjust.
 Identities = 25/65 (38%), Positives = 31/65 (47%), Gaps = 7/65 (10%)
 Frame = +3

Query: 13   SRGSVLLPCPSPSGNTMAR------CP-MLSSSHNQDHSGRWTAVWTSLWKTPIILWLLL 65
            SR S+L+P   PS  T+        CP +L + H Q H+ R T   T L  T I L LLL
Sbjct: 1254 SRVSLLVPTIQPSLRTIRHKHRRXSCPHILYTXHGQTHTDRQTXTHTYLCSTAINLRLLL 1433

Query: 66   SDTSL 70
                L
Sbjct: 1434 KKGDL 1448
>04901
          Length = 1042

 Score = 32.7 bits (73), Expect = 0.97,   Method: Compositional matrix adjust.
 Identities = 28/98 (28%), Positives = 41/98 (41%), Gaps = 1/98 (1%)
 Frame = +1

Query: 557 GVHGYAFLNTNNGYILSHPDLRPLY-REGKKLRPKPNYNSVDLSEVEWEDQAEILRTAMI 615
           G     F  T+ G   S+  + P +   G K+ P P  +S  +    W     IL+  ++
Sbjct: 322 GTKKQKFTKTHTGPNQSNTFVNPNFVNNGGKMPPMPKQSSRAI----W---GSILQEQIL 480

Query: 616 NGETGSHSMDVKVPLDKGKRVLFLTNDYFFTDISDTPF 653
             E GS SMD K+P D+       + DY      D PF
Sbjct: 481 TSEVGSFSMDTKLPSDRD----VESYDYSRAKDDDRPF 582
>02835
          Length = 1996

 Score = 31.6 bits (70), Expect = 2.1,   Method: Compositional matrix adjust.
 Identities = 24/67 (35%), Positives = 34/67 (50%)
 Frame = +3

Query: 526 NETRSHGILLGVVGSDVTLRELMKLAPRYKLGVHGYAFLNTNNGYILSHPDLRPLYREGK 585
            + RSH ILL V  + V L +L K        VH +  L  ++ +I+SH    PL    K
Sbjct: 879 QKRRSHYILL-VS*NIVCLMQLQK--------VHRFLLLQCSSSFIISHK*HYPLPTHHK 1031

Query: 586 KLRPKPN 592
           +L+PK N
Sbjct: 1032QLKPKQN 1052
>17044
          Length = 946

 Score = 30.8 bits (68), Expect = 3.2,   Method: Composition-based stats.
 Identities = 17/53 (32%), Positives = 30/53 (56%), Gaps = 1/53 (1%)
 Frame = -1

Query: 167 SLVFNYYNSVLINEKDDKGNYVELGAEFLLESDA-HFSNLRVNVSMSSVQLPT 218
           S + +YYN  ++N+  +K N   +  ++  +  A H SNL+V  S  ++ LPT
Sbjct: 850 SHIHSYYNV*VLNKHSNKYNCTNMSNKYHRQIRAYHISNLKVLCSFITITLPT 692
>09227
          Length = 1244

 Score = 30.8 bits (68), Expect = 3.2,   Method: Compositional matrix adjust.
 Identities = 14/43 (32%), Positives = 25/43 (58%)
 Frame = -3

Query: 888 KSCEDTDLDCFVIDNNGFVLISERPQEMGRLLGEADGALMKQL 930
           K C   D+D   I++NG +++  R   +G L+ +A+   MKQ+
Sbjct: 615 KKCNLKDVDTITINSNGVIILQAR---VGSLITQANDNTMKQV 496
>11168
          Length = 1167

 Score = 30.4 bits (67), Expect = 4.7,   Method: Compositional matrix adjust.
 Identities = 14/43 (32%), Positives = 25/43 (58%)
 Frame = -2

Query: 888 KSCEDTDLDCFVIDNNGFVLISERPQEMGRLLGEADGALMKQL 930
           K C   D+D   I++NG +++  R   +G L+ +A+   MKQ+
Sbjct: 575 KKCNLKDVDTITINSNGVIILQAR---VGSLITQANDNTMKQV 456
>06146
          Length = 541

 Score = 30.0 bits (66), Expect = 5.5,   Method: Composition-based stats.
 Identities = 19/56 (33%), Positives = 28/56 (50%), Gaps = 3/56 (5%)
 Frame = -2

Query: 856 AAAVGIQMQADYLQRQ-FWAAMQQCNAVEGPCLKSCEDT--DLDCFVIDNNGFVLI 908
           A   G+   + YLQ+    AA  Q     GPCL  C+D   + +C + DNN  +L+
Sbjct: 420 ATFSGVMCLSLYLQKGCHSAAALQIKRYSGPCLMFCDDCPWEQNCGINDNNDILLL 253
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|21312189|ref|NP_081197.1| HESB like domain containing
2 [Mus musculus]
         (129 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

00806                                                                  40   3e-04
09698                                                                  36   0.004
31939                                                                  29   0.68 
>00806
          Length = 1952

 Score = 40.0 bits (92), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 21/71 (29%), Positives = 36/71 (50%), Gaps = 1/71 (1%)
 Frame = +1

Query: 60  LSYSLEYTKTKGDSDEEVIQDGVRVFIEKKAQLTLLGTEMDYVEDKLSSEF-VFNNPNIK 118
             Y  E     G+ D    +DG RV I+K +   + G+ +D+ ++ + S F + +NP  +
Sbjct: 328 FQYKFELDTEVGEDDRVFEKDGARVVIDKDSLDYVKGSTVDFYQELIRSAFRIVDNPLAE 507

Query: 119 GTCGCGESFHV 129
             C CG SF +
Sbjct: 508 QGCSCGASFSI 540
>09698
          Length = 412

 Score = 36.2 bits (82), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 16/52 (30%), Positives = 31/52 (59%), Gaps = 1/52 (1%)
 Frame = -1

Query: 79  QDGVRVFIEKKAQLTLLGTEMDYVEDKLSSEF-VFNNPNIKGTCGCGESFHV 129
           +DG RV I++ +   + G+ +D+ ++ + S F + +NP  +  C CG SF +
Sbjct: 382 KDGARVVIDRDSLDYVKGSTVDFYQELIRSAFRIVDNPLAEQGCSCGASFSI 227
>31939
          Length = 878

 Score = 28.9 bits (63), Expect = 0.68,   Method: Compositional matrix adjust.
 Identities = 12/26 (46%), Positives = 17/26 (65%)
 Frame = -1

Query: 18  LQPTRAALTLTPSAVNKIKQLLKDKP 43
           + PTRA L L P  ++K+K L K+ P
Sbjct: 212 ITPTRATLCLWPDTMSKVKSLAKESP 135
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|160333863|ref|NP_035727.2| tight junction protein 2
[Mus musculus]
         (1167 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

27435                                                                  44   4e-04
38751                                                                  44   5e-04
03831                                                                  38   0.022
29974                                                                  37   0.062
29705                                                                  37   0.063
01502                                                                  34   0.33 
02951                                                                  34   0.35 
27345                                                                  34   0.40 
20073                                                                  32   1.6  
19469                                                                  31   2.4  
03499                                                                  31   3.0  
>27435
          Length = 456

 Score = 43.9 bits (102), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 27/113 (23%), Positives = 60/113 (53%), Gaps = 3/113 (2%)
 Frame = +1

Query: 758 LNTVRQIIEQDKHALLDVTPKAVDLLNYTQWFPIVIFFNPDSRQGVKTIRQRLS---PTS 814
           +  VRQ+I+Q +  +L++ P+++  L  T+  P +IF +P   + ++ ++  L    PT 
Sbjct: 115 VEAVRQVIQQGRICILNLGPESLKNLRETELKPYIIFISPPXMEKLRQLQMALGKPRPTD 294

Query: 815 NKSSRKLFDQANKLKKTCSHLFTATINVNSANDGWFGSLKDSIQQQQNEAVWV 867
           ++  +++ ++  ++++  SH F   + VN   +  F  L   I + + E  WV
Sbjct: 295 DQ-VKEVIERGREMEEMYSHYFDYIL-VNMELNRAFDELLQEINRIETEPQWV 447
>38751
          Length = 329

 Score = 43.5 bits (101), Expect = 5e-04,   Method: Composition-based stats.
 Identities = 26/54 (48%), Positives = 33/54 (61%), Gaps = 2/54 (3%)
 Frame = +3

Query: 501 VGLRLAGGNDVG--IFVAGIQEGTSAEQEGLQEGDQILKVNTQDFRGLVREDAV 552
           VG++  GG + G  I V  I+EG  AEQ+GL  GD+IL VN  DF  L   +AV
Sbjct: 3   VGIK--GGKEYGTPIVVYVIEEGCQAEQQGLNIGDRILDVNGTDFTHLTHAEAV 158
>03831
          Length = 1143

 Score = 38.1 bits (87), Expect = 0.022,   Method: Compositional matrix adjust.
 Identities = 23/67 (34%), Positives = 36/67 (53%), Gaps = 2/67 (2%)
 Frame = +3

Query: 31  NPHFENGETSIVISDVLPGGPAD-GLLQENDRVVMVNGTPMEDVLHSFAVQQLRKSG-KI 88
           N H E  +    I  V P  PA+ G L+E DR++ VNG  +E   H+  +Q ++  G K 
Sbjct: 627 NLHAEKDKPGQYIGSVDPNSPAETGGLKEGDRIIEVNGENIETTNHTAVIQNIKSRGDKT 806

Query: 89  AAIVVKR 95
           + +VV +
Sbjct: 807 SMLVVDK 827

 Score = 32.7 bits (73), Expect = 0.78,   Method: Compositional matrix adjust.
 Identities = 21/64 (32%), Positives = 32/64 (50%), Gaps = 1/64 (1%)
 Frame = +3

Query: 31  NPHFENGETSIVISDVLPGGPADGL-LQENDRVVMVNGTPMEDVLHSFAVQQLRKSGKIA 89
           N H E G+    I  V  G PA+   L+  DR+V VNGT + +  H   V +++  G   
Sbjct: 180 NLHAEKGKAGQFIGKVDEGSPAEAAGLKAGDRIVEVNGTNIGNENHQQVVGRIKAGGDET 359

Query: 90  AIVV 93
            ++V
Sbjct: 360 RLLV 371
>29974
          Length = 344

 Score = 36.6 bits (83), Expect = 0.062,   Method: Compositional matrix adjust.
 Identities = 14/38 (36%), Positives = 23/38 (60%)
 Frame = +1

Query: 760 TVRQIIEQDKHALLDVTPKAVDLLNYTQWFPIVIFFNP 797
           +V+++ EQ +H +LDV+  A+  L     +PI IF  P
Sbjct: 202 SVKEVAEQGRHCILDVSGNAIKRLQVAGLYPIAIFIKP 315
>29705
          Length = 674

 Score = 36.6 bits (83), Expect = 0.063,   Method: Compositional matrix adjust.
 Identities = 19/47 (40%), Positives = 28/47 (59%), Gaps = 1/47 (2%)
 Frame = -1

Query: 510 DVGIFVAGIQEGTSAEQEG-LQEGDQILKVNTQDFRGLVREDAVLYL 555
           D GIF+  + EG SAEQ+G +   D++L VN  +   +  E+AV  L
Sbjct: 368 DNGIFITKVIEGGSAEQDGRIAVMDRLLAVNEHNLEDVTHEEAVAAL 228
>01502
          Length = 1949

 Score = 34.3 bits (77), Expect = 0.33,   Method: Composition-based stats.
 Identities = 18/43 (41%), Positives = 27/43 (62%)
 Frame = +1

Query: 510 DVGIFVAGIQEGTSAEQEGLQEGDQILKVNTQDFRGLVREDAV 552
           D GI+V  I E + A + GLQ  D+IL++N +DF  +  + AV
Sbjct: 28  DKGIYVTFIYENSPAARCGLQLHDKILQLNGKDFTVVTHKQAV 156
>02951
          Length = 1076

 Score = 33.9 bits (76), Expect = 0.35,   Method: Composition-based stats.
 Identities = 19/46 (41%), Positives = 28/46 (60%)
 Frame = +2

Query: 507 GGNDVGIFVAGIQEGTSAEQEGLQEGDQILKVNTQDFRGLVREDAV 552
           G  D GI+V  I E + A + GLQ  D+IL++N +DF  +  + AV
Sbjct: 5   GYPDKGIYVTFIYENSPAARCGLQLHDKILQLNGKDFTVVTHKQAV 142
>27345
          Length = 496

 Score = 33.9 bits (76), Expect = 0.40,   Method: Compositional matrix adjust.
 Identities = 17/58 (29%), Positives = 31/58 (53%)
 Frame = +3

Query: 307 IFIKEMTRTGLATKDGNLHEGDIILKINGTVTENMSLTDARKLIEKSRGKLQLVVLRD 364
           IFIK +T  G A KDG +   D I++++G     ++   A  ++  + G++   + RD
Sbjct: 27  IFIKTLTDGGAAQKDGRIQVNDQIIEVDGKSLVGVTQAYAASVLRNTSGQVTFHIGRD 200
>20073
          Length = 582

 Score = 32.0 bits (71), Expect = 1.6,   Method: Composition-based stats.
 Identities = 23/75 (30%), Positives = 38/75 (50%)
 Frame = +3

Query: 300 GLRLGSQIFIKEMTRTGLATKDGNLHEGDIILKINGTVTENMSLTDARKLIEKSRGKLQL 359
           G    S I+I  +   G+A +   L  GD +L +NG   E      A +L++ ++G ++L
Sbjct: 27  GKEQSSPIYISRIIPGGVADRLNCLKRGDQLLSVNGVSVEGEYHEKAVELLKLAQGSVRL 206

Query: 360 VVLRDSKQTLINIPA 374
           VV R + Q L  + A
Sbjct: 207 VV-RYTPQILEEMEA 248
>19469
          Length = 428

 Score = 31.2 bits (69), Expect = 2.4,   Method: Compositional matrix adjust.
 Identities = 14/41 (34%), Positives = 22/41 (53%)
 Frame = -1

Query: 587 FFIRSHFECEKETPQSLAFTRGEVFRVVDTLYDGKLGHWLA 627
           F  ++ ++   ETP  LAF RG+V  +++    G  G WL 
Sbjct: 365 FLAKALYDNIAETPDELAFRRGDVITILEQDTAGLDGWWLC 243
>03499
          Length = 1247

 Score = 30.8 bits (68), Expect = 3.0,   Method: Compositional matrix adjust.
 Identities = 16/38 (42%), Positives = 20/38 (52%)
 Frame = -3

Query: 529 LQEGDQILKVNTQDFRGLVREDAVLYLLEIPKGETVTI 566
           L+ GD I+ VNT    G   +D V     I  GETVT+
Sbjct: 849 LKTGDVIVFVNTTCVLGYTHQDVVSLFQTISPGETVTL 736
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6753234|ref|NP_033914.1| calcium channel,
voltage-dependent, alpha2/delta subunit 1 isoform e [Mus musculus]
         (1084 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

19289                                                                  44   4e-04
38178                                                                  38   0.025
05829                                                                  31   3.5  
00262                                                                  30   5.1  
24081                                                                  30   7.5  
>19289
          Length = 734

 Score = 43.5 bits (101), Expect = 4e-04,   Method: Composition-based stats.
 Identities = 38/162 (23%), Positives = 66/162 (40%), Gaps = 9/162 (5%)
 Frame = +3

Query: 450 YLDALELGLVITGTLPVFNVTGQSENKTNLKNQLILGVMGVDVSLEDIKRLTPRFTLCPN 509
           Y+D  +  L ++ + P F+V      +  L     +G++GVD+ +EDI +    +    +
Sbjct: 18  YIDEADGALTLSISQPCFHVPVSERERVQL-----MGMVGVDLHMEDIAQDITYYNNNDH 182

Query: 510 GYYFAIDPNGYVLLHPNLQPKNPKSQEPVTLDFLDAELENEIKVEIRNKMIDGESGEKTF 569
            Y F I  +GY + HP  Q     S +P+  D    E        +R+ ++  E G  + 
Sbjct: 183 SYAFLITTHGYTIQHPVFQRPLRTSFQPMHTDIRHFEQHPGFDT-VRHTILSREEGHTSL 359

Query: 570 RTLVKS---------QDERYIDKGNRTYTWTPVNGTDYSLAL 602
              V +         Q ER +      Y W  V+   Y + L
Sbjct: 360 LLEVTNHTAPDGQVIQVERVV-----KYFWKKVDNVPYIVVL 470
>38178
          Length = 772

 Score = 37.7 bits (86), Expect = 0.025,   Method: Composition-based stats.
 Identities = 26/105 (24%), Positives = 48/105 (45%), Gaps = 10/105 (9%)
 Frame = +1

Query: 189 LDEVFKRNRDEDPTLLWQVFGSATGLARYYPASP--WVDNSRTPNKI-------DLYDVR 239
           L EV++ N    P+L WQ F S  GL   +PAS   W+ +  +P          +++D R
Sbjct: 1   LTEVWRSNTHYFPSLKWQYFISVLGLHNEFPASSFRWLGDCHSPTGSRNRHSCHNIHDTR 180

Query: 240 RRPWYIQG-AASPKDMLILVDVSGSVSGLTLKLIRTSVSEMLETL 283
            R  ++       K ++I++D   S+S   L+  +     ++ + 
Sbjct: 181 HRDVFLSTIQPQRKHVVIMMDHGNSMSVTQLRTAKAIAKHLIASF 315
>05829
          Length = 1939

 Score = 30.8 bits (68), Expect = 3.5,   Method: Composition-based stats.
 Identities = 25/77 (32%), Positives = 40/77 (51%), Gaps = 2/77 (2%)
 Frame = +3

Query: 900 AYVPSIADILQIGWWATAAAWSILQQLLLSLTFPRLLEAVEMEEDDFTASLSK--QSCIT 957
           A+  ++ D   +  W+TA   S L +          L+ VE+ E + T S SK  Q+C+ 
Sbjct: 177 AHTHTLTDSHTLPLWSTAINLSFLLK-------KGDLKKVELSE*NITHSESKPEQTCVY 335

Query: 958 EQTQYFFKNDTKSFSGL 974
           ++ QYF K+ TKS + L
Sbjct: 336 QKVQYFNKS-TKSITKL 383
>00262
          Length = 1036

 Score = 30.0 bits (66), Expect = 5.1,   Method: Compositional matrix adjust.
 Identities = 31/130 (23%), Positives = 52/130 (40%), Gaps = 2/130 (1%)
 Frame = -1

Query: 709 GVKARFVVTDGGITRVYPKEAGENWQENPETYEDSFYKRSLDNDNYVFTAPYFNKSGPGA 768
           GV+ R V  D  +  V   + GE   ++P     + Y R +DND     +  F   G   
Sbjct: 967 GVQVRIV--DEHLQDVGEGQTGEIIAKSP-----ALYSRYIDNDEAAKKS--FTPDGWFR 815

Query: 769 YESGIMVSKAVELYIQGKLLKPAVVGIKIDVNSWIENFTK--TSIRDPCAGPVCDCKRNS 826
            +     ++   +   G+       G  +    W+E   +   S+RD C  PV D   + 
Sbjct: 814 TDDMGCFNQDKHIIHLGRRTDAITRGAYLCYPGWLETLLRRSPSVRDVCVVPVADPVLHH 635

Query: 827 DVMDCVILDD 836
           ++  CVI +D
Sbjct: 634 EICACVIPND 605
>24081
          Length = 801

 Score = 29.6 bits (65), Expect = 7.5,   Method: Composition-based stats.
 Identities = 19/68 (27%), Positives = 32/68 (47%), Gaps = 6/68 (8%)
 Frame = -1

Query: 782 YIQGKLLKPAVVGIKIDVNS-----WIENFTKTSIRDPCAGPVCDCKRNSDVMDCVILDD 836
           ++ G+   P +  +K+ +       W++    T I  PC  PV   +     MDC ++DD
Sbjct: 255 FVFGEQFCPNIFWLKLQIQX*XVCLWLDLNEXTDILKPC**PVVLARH---FMDCTLIDD 85

Query: 837 -GGFLLMA 843
            G FL+ A
Sbjct: 84  IGSFLIQA 61
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|9910142|ref|NP_064390.1| CDC42 effector protein (Rho
GTPase binding) 4 [Mus musculus]
         (349 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

10993                                                                  42   4e-04
>10993
          Length = 775

 Score = 42.0 bits (97), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 18/32 (56%), Positives = 20/32 (62%)
 Frame = -1

Query: 22  LTAEMISAPLGDFRHTMHVGRAGDAFGDTSFL 53
           L  EMI AP  D RHT H+G  G  FGD SF+
Sbjct: 694 LRTEMIGAPQNDLRHTGHIGYDGAVFGDVSFI 599
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|28175675|gb|AAH45114.1| Cngb1 protein [Mus musculus]
         (866 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

24780                                                                  43   5e-04
14364                                                                  35   0.13 
20517                                                                  32   0.85 
07018                                                                  31   2.2  
14674                                                                  31   2.5  
00648                                                                  26   3.7  
34403                                                                  29   8.4  
02489                                                                  29   8.7  
>24780
          Length = 572

 Score = 43.1 bits (100), Expect = 5e-04,   Method: Composition-based stats.
 Identities = 18/34 (52%), Positives = 24/34 (70%)
 Frame = +3

Query: 657 NRRTANVVAHGFTNLFILDKKDLNEILVHYPESQ 690
           NRRTA+V + G+TN+F L K D  E +  YPE+Q
Sbjct: 3   NRRTADVRSSGYTNVFTLSKHDFEEAMNEYPEAQ 104
>14364
          Length = 1308

 Score = 35.0 bits (79), Expect = 0.13,   Method: Composition-based stats.
 Identities = 20/59 (33%), Positives = 31/59 (52%), Gaps = 2/59 (3%)
 Frame = +1

Query: 272 MYILWLFFVVLAWNWNC-WLIPVRWAFPYQRADNIHFWL-LMDYLCDFIYLLDITVFQM 328
           ++I ++FFV+  WNWN    I VR++  Y     +  WL   D   D IY L  ++ +M
Sbjct: 49  VWI*FMFFVLFCWNWNIEGFISVRFSHVYYNPRGVICWL**FDVTTDNIYFLLFSLTRM 225
>20517
          Length = 749

 Score = 32.3 bits (72), Expect = 0.85,   Method: Compositional matrix adjust.
 Identities = 26/74 (35%), Positives = 31/74 (41%), Gaps = 3/74 (4%)
 Frame = +3

Query: 614 REMYIIQAGQV---QVLGGPDGKAVLVTLKAGSVFGEISLLAVGGGNRRTANVVAHGFTN 670
           R  Y I +G V   Q          LVTL  G  FGE   LAV  G+RR A V       
Sbjct: 15  RSFYFILSGTVVVTQFERQYSTTRTLVTLDQGMSFGE---LAVITGSRRQATVSTMTEVE 185

Query: 671 LFILDKKDLNEILV 684
           L  +  KD  +I +
Sbjct: 186 LLCISAKDFEDIFM 227
>07018
          Length = 623

 Score = 30.8 bits (68), Expect = 2.2,   Method: Composition-based stats.
 Identities = 25/75 (33%), Positives = 35/75 (46%), Gaps = 6/75 (8%)
 Frame = -2

Query: 250 KFKRRPLK-MYRFPQSIDPLTNLMYILWLFFVVLAWNWNCWLIPV---RWAFPYQRADNI 305
           K +R+PLK +  F QS+ P +     +W     LAW ++CW I     +   PY    + 
Sbjct: 391 KLERKPLKFILSFHQSVLPQS-----IW----TLAWRYSCWCIEFVR*KVISPYNSRSD* 239

Query: 306 HFWLLMDYL--CDFI 318
           H  LL   L  C FI
Sbjct: 238 H*VLLPQALSNCHFI 194
>14674
          Length = 992

 Score = 30.8 bits (68), Expect = 2.5,   Method: Compositional matrix adjust.
 Identities = 18/66 (27%), Positives = 34/66 (51%), Gaps = 6/66 (9%)
 Frame = +2

Query: 288 CWLIPVRWAFPYQRADNIHFWLLM---DYLCDFIYLLDITV---FQMRLQFVKGGDIITD 341
           CW+   +WA    + + +H +LL+   + L DFI +L+ T+   F+  +Q    G     
Sbjct: 287 CWVPGSQWALEQAKQNVLHNYLLVGVTEELADFIAVLEATLPRFFKGAMQLFNNGRKSHL 466

Query: 342 KKEMRN 347
           +K ++N
Sbjct: 467 RKTLKN 484
>00648
          Length = 2102

 Score = 26.2 bits (56), Expect(2) = 3.7,   Method: Composition-based stats.
 Identities = 8/25 (32%), Positives = 14/25 (56%)
 Frame = +3

Query: 238  AEEEHYCDMLCCKFKRRPLKMYRFP 262
            A ++H CD   C+  R+P+ +   P
Sbjct: 1893 ARDQHACDASDCRNSRKPISLMDLP 1967

 Score = 22.3 bits (46), Expect(2) = 3.7,   Method: Composition-based stats.
 Identities = 8/24 (33%), Positives = 12/24 (50%)
 Frame = +1

Query: 268  LTNLMYILWLFFVVLAWNWNCWLI 291
            + N +Y+   FF  L  NW  W +
Sbjct: 2005 ILNCLYLHIFFFXPLNXNWLQWCV 2076
>34403
          Length = 483

 Score = 28.9 bits (63), Expect = 8.4,   Method: Composition-based stats.
 Identities = 18/42 (42%), Positives = 26/42 (61%)
 Frame = +3

Query: 597 SVVYLPNDYVCKKGEIGREMYIIQAGQVQVLGGPDGKAVLVT 638
           +VV LP + V  KG I  +++ +  G+VQVL GPD   VL +
Sbjct: 171 TVVQLPQEPVRPKG-IQCDLHPLDPGKVQVLWGPDRPPVLAS 293
>02489
          Length = 1716

 Score = 28.9 bits (63), Expect = 8.7,   Method: Composition-based stats.
 Identities = 14/44 (31%), Positives = 21/44 (47%)
 Frame = +3

Query: 246 MLCCKFKRRPLKMYRFPQSIDPLTNLMYILWLFFVVLAWNWNCW 289
           M CC F    L M      I  +T   Y++ ++ ++L WNW  W
Sbjct: 54  MFCCFFGLICLIM*LMFICI--ITTFFYVVLMYSLILLWNWEVW 179
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6679915|ref|NP_032099.1| gamma-aminobutyric acid
(GABA-A) receptor, subunit gamma 2 isoform 1 [Mus musculus]
         (474 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

36607                                                                  42   6e-04
>36607
          Length = 704

 Score = 42.0 bits (97), Expect = 6e-04,   Method: Compositional matrix adjust.
 Identities = 41/170 (24%), Positives = 75/170 (44%), Gaps = 5/170 (2%)
 Frame = -3

Query: 130 TIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLTIDAEC 189
            I  +RL S+   KIW+PD    N   AD       N ++   + G +L+  +  + + C
Sbjct: 486 NISDVRLPSD---KIWLPDIVLYNF--ADERLKEQRNALVVTSSTGDLLWMPQAILRSSC 322

Query: 190 QLQLHNFPMDEHSCPLEFSSYGYP--REEIVYQWKRSSVEVGD---TRSWRLYQFSFVGL 244
                 FP DE  C L+F S+ Y   + +I +   R++ ++ D      W + Q +    
Sbjct: 321 SFDTLLFPFDEQFCILKFGSWSYSGFKLDIHFLPNRTNFDLSDYIVNTEWAILQNT--AQ 148

Query: 245 RNTTEVVKTTSGDYVVMSVYFDLSRRMGYFTIQTYIPCTLIVVLSWVSFW 294
           RN  +        +  +     + RR+ ++T    +PC L+ +L+ + FW
Sbjct: 147 RNV-KYYTCCPDPFPDLQFKLRIKRRVAFYTFILIMPCALLSLLTLLIFW 1
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|20982845|ref|NP_631888.1| pigpen [Mus musculus]
         (518 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

11758                                                                  42   7e-04
00302                                                                  38   0.011
03406                                                                  37   0.019
11019                                                                  36   0.046
26197                                                                  35   0.086
01937                                                                  34   0.11 
17775                                                                  34   0.14 
02415                                                                  32   0.84 
03903                                                                  31   0.99 
33516                                                                  31   1.4  
03744                                                                  30   2.8  
16016                                                                  29   3.8  
30672                                                                  29   5.1  
20488                                                                  29   5.1  
19868                                                                  28   8.6  
>11758
          Length = 477

 Score = 42.0 bits (97), Expect = 7e-04,   Method: Composition-based stats.
 Identities = 15/22 (68%), Positives = 16/22 (72%)
 Frame = -3

Query: 419 WKCPNPTCENMNFSWRNECNQC 440
           W C NP C N NF WRNECN+C
Sbjct: 151 WTCVNPDCGNNNFRWRNECNRC 86
>00302
          Length = 927

 Score = 37.7 bits (86), Expect = 0.011,   Method: Compositional matrix adjust.
 Identities = 27/97 (27%), Positives = 43/97 (44%), Gaps = 1/97 (1%)
 Frame = -1

Query: 267 RHDSEQDNSD-NNTIFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRETGK 325
           RH  +++N D N  + + GL        + + F + G I          + +  DR+TG+
Sbjct: 501 RHQGDRENPDPNRCLGIFGLSLYTQERGLREVFGRYGHISE--------VQVVYDRQTGR 346

Query: 326 LKGEATVSFDDPPSAKAAIDWFDGKEFSGNPIKVSFA 362
            +G A V F     A  A D  +G E  G  I+V F+
Sbjct: 345 SRGFAFVYFKSSEDAHEAKDRCNGIEIDGRKIRVDFS 235
>03406
          Length = 1292

 Score = 37.0 bits (84), Expect = 0.019,   Method: Compositional matrix adjust.
 Identities = 23/86 (26%), Positives = 42/86 (48%)
 Frame = +3

Query: 259 GGPRDQGSRHDSEQDNSDNNTIFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLY 318
           GG +   +  D+E++N D+  IFV GL      + + +YF++ G + +          L 
Sbjct: 183 GGDQAMETGGDAEEENEDDRKIFVGGLSWETXSKHLREYFEKFGEVTS--------CTLK 338

Query: 319 TDRETGKLKGEATVSFDDPPSAKAAI 344
           TD ++GK +G   V F +  +  A +
Sbjct: 339 TDLDSGKSRGFGFVVFKEAATVDAVV 416
>11019
          Length = 552

 Score = 35.8 bits (81), Expect = 0.046,   Method: Compositional matrix adjust.
 Identities = 20/57 (35%), Positives = 30/57 (52%)
 Frame = -1

Query: 280 IFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEATVSFDD 336
           IFV GL  + T+E + +YFK  G I+           L  D+ T + +G A V+FD+
Sbjct: 228 IFVGGLSSSTTVEDIKNYFKAYGTIEEA--------TLMFDKVTSRHRGFAFVTFDN 82
>26197
          Length = 1365

 Score = 34.7 bits (78), Expect = 0.086,   Method: Compositional matrix adjust.
 Identities = 21/79 (26%), Positives = 38/79 (48%)
 Frame = -2

Query: 266  SRHDSEQDNSDNNTIFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRETGK 325
            S H   ++N D+  IFV GL    + + + +YF++ G + +          L TD ++GK
Sbjct: 1334 SGHYGREENEDDRKIFVGGLSWETSSKHLREYFEKFGEVTS--------CTLKTDLDSGK 1179

Query: 326  LKGEATVSFDDPPSAKAAI 344
             +G   V F +  +  A +
Sbjct: 1178 SRGFGFVVFKEAVTVDAVV 1122
>01937
          Length = 1320

 Score = 34.3 bits (77), Expect = 0.11,   Method: Compositional matrix adjust.
 Identities = 22/72 (30%), Positives = 35/72 (48%)
 Frame = -1

Query: 269  DSEQDNSDNNTIFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRETGKLKG 328
            DS+   +  + IFV GL  + T+E   +YFK  G I+           L  D+ T + +G
Sbjct: 1242 DSKTMVTKTSKIFVGGLSSSTTVEDXKNYFKAYGTIEEA--------TLMFDKVTSRHRG 1087

Query: 329  EATVSFDDPPSA 340
             A V+FD+  + 
Sbjct: 1086 FAFVTFDNESTV 1051
>17775
          Length = 1282

 Score = 33.9 bits (76), Expect = 0.14,   Method: Compositional matrix adjust.
 Identities = 16/36 (44%), Positives = 22/36 (61%)
 Frame = -2

Query: 322 ETGKLKGEATVSFDDPPSAKAAIDWFDGKEFSGNPI 357
           E GK +G   VSF++P  A+ A+D  +G E SG  I
Sbjct: 546 EDGKSRGFGFVSFEEPEGAEKAVDEINGTEVSGRII 439
>02415
          Length = 2763

 Score = 31.6 bits (70), Expect = 0.84,   Method: Compositional matrix adjust.
 Identities = 21/65 (32%), Positives = 31/65 (47%)
 Frame = -1

Query: 272  QDNSDNNTIFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEAT 331
            Q ++    IFV GL  + T  S+ +YF + G I            + TDR+TGK +G   
Sbjct: 1944 QKDTTYTKIFVGGLPYHTTDHSLREYFDKFGDIDEAV--------VITDRQTGKSRGYGF 1789

Query: 332  VSFDD 336
            V+  D
Sbjct: 1788 VTMAD 1774
>03903
          Length = 983

 Score = 31.2 bits (69), Expect = 0.99,   Method: Compositional matrix adjust.
 Identities = 21/83 (25%), Positives = 43/83 (51%)
 Frame = -1

Query: 280 IFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEATVSFDDPPS 339
           ++++ L + VT E +   F +   +  +K+  + + ++   +E G++KG+A V+      
Sbjct: 452 LYIKNLSKQVTEEDLHWVFGRY--VNWDKEEEKSIFDIRLMKE-GRMKGQAFVTLGTEEQ 282

Query: 340 AKAAIDWFDGKEFSGNPIKVSFA 362
           A+ A+   +   F G PI V FA
Sbjct: 281 ARKAVKDTNAFVFKGKPIAVHFA 213
>33516
          Length = 449

 Score = 30.8 bits (68), Expect = 1.4,   Method: Compositional matrix adjust.
 Identities = 20/65 (30%), Positives = 30/65 (46%)
 Frame = +1

Query: 280 IFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEATVSFDDPPS 339
           IFV GL  +   +S+  YF Q G I            +  +++TGK +G   VSF DP +
Sbjct: 160 IFVGGLSWDTDQDSLQGYFSQFGEITD--------CIVMMNQQTGKSRGFGFVSFKDPST 315

Query: 340 AKAAI 344
               +
Sbjct: 316 VDVIL 330
>03744
          Length = 3486

 Score = 29.6 bits (65), Expect = 2.8,   Method: Compositional matrix adjust.
 Identities = 20/86 (23%), Positives = 37/86 (43%)
 Frame = -1

Query: 276  DNNTIFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEATVSFD 335
            D   +F+  L +    + +   F   G + + K        ++ D++T   K    VS+D
Sbjct: 3222 DGANLFIYHLPQEFGDQDLMQMFMPFGNVVSAK--------VFIDKQTNLSKCFGFVSYD 3067

Query: 336  DPPSAKAAIDWFDGKEFSGNPIKVSF 361
             P +A+AAI   +G +     +KV  
Sbjct: 3066 SPLAAQAAITSMNGFQIGMKRLKVQL 2989
>16016
          Length = 1364

 Score = 29.3 bits (64), Expect = 3.8,   Method: Compositional matrix adjust.
 Identities = 12/22 (54%), Positives = 15/22 (68%)
 Frame = -1

Query: 315 INLYTDRETGKLKGEATVSFDD 336
           IN+  D+ TGK +G   VSFDD
Sbjct: 965 INMIKDKSTGKFRGFCFVSFDD 900
>30672
          Length = 877

 Score = 28.9 bits (63), Expect = 5.1,   Method: Compositional matrix adjust.
 Identities = 25/86 (29%), Positives = 38/86 (44%)
 Frame = +3

Query: 277 NNTIFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEATVSFDD 336
           + T+FV+ L    + E + + F+Q+G +KT          +   +E GK +G   V F  
Sbjct: 9   SKTLFVRNLPFETSNEKLLEAFEQVGPLKTA--------FVVAGKEPGKCRGFGYVQFSM 164

Query: 337 PPSAKAAIDWFDGKEFSGNPIKVSFA 362
              A  A D       SG  I +SFA
Sbjct: 165 LEDAIKAKDTVT--HCSGRKISLSFA 236
>20488
          Length = 3281

 Score = 28.9 bits (63), Expect = 5.1,   Method: Compositional matrix adjust.
 Identities = 24/104 (23%), Positives = 45/104 (43%), Gaps = 3/104 (2%)
 Frame = +2

Query: 261  PRDQGSRHDSEQDNS---DNNTIFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINL 317
            P+ Q  + +S   +S   D   +F+  L +    + +   F   G + + K        +
Sbjct: 2648 PQAQMQQANSAGKHSEGPDGANLFIYHLPQEFGDQDLMQMFMPFGNVVSAK--------V 2803

Query: 318  YTDRETGKLKGEATVSFDDPPSAKAAIDWFDGKEFSGNPIKVSF 361
            + D++T   K    VS+D P +A+AAI   +G +     +KV  
Sbjct: 2804 FIDKQTNLSKCFGFVSYDSPLAAQAAITSMNGFQIGMKRLKVQL 2935
>19868
          Length = 434

 Score = 28.1 bits (61), Expect = 8.6,   Method: Composition-based stats.
 Identities = 13/26 (50%), Positives = 17/26 (65%)
 Frame = +2

Query: 280 IFVQGLGENVTIESVADYFKQIGIIK 305
           IFV GL    T+E V +YF+Q G I+
Sbjct: 272 IFVGGLSAPTTLEDVKNYFEQFGPIE 349
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6678133|ref|NP_033299.1| signal recognition particle
14 [Mus musculus]
         (110 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

31943                                                                  39   7e-04
11855                                                                  25   5.9  
>31943
          Length = 283

 Score = 38.5 bits (88), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 18/41 (43%), Positives = 24/41 (58%)
 Frame = +1

Query: 54 NKCLLRATDGKRKISTVVSSKEVNKFQMAYSNLLRANMDGL 94
          N CL+RA    +KISTVVS + V      Y   +++ MDGL
Sbjct: 28 NMCLMRAKCKSKKISTVVSQENVPTMMAMYCQFMKSKMDGL 150
>11855
          Length = 1574

 Score = 25.4 bits (54), Expect = 5.9,   Method: Composition-based stats.
 Identities = 14/34 (41%), Positives = 18/34 (52%)
 Frame = +1

Query: 11  TELTRLFQKCRSSGSVFITLKKYDGRTKPIPRKS 44
           T   +LF  CR+SG    T+  YDGR   +P  S
Sbjct: 358 TTTVQLF--CRASGYPEPTITWYDGRNNSLPDNS 453
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6678333|ref|NP_033402.1| Tg737 protein [Mus musculus]
         (824 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

01124                                                                  43   7e-04
28154                                                                  35   0.11 
18279                                                                  30   3.6  
10994                                                                  30   3.7  
03857                                                                  30   4.0  
>01124
          Length = 1372

 Score = 42.7 bits (99), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 37/132 (28%), Positives = 61/132 (46%), Gaps = 26/132 (19%)
 Frame = -3

Query: 462 LENEF----AQASSYADLA---VNSDRYNPSALTNKGNTVFANGDYEKAAEFYKEALR-- 512
           LE+E+    A+A   ADLA   +  +  NP  L +KGN  FA+G+Y+ A   Y  ALR  
Sbjct: 842 LEDEWLQKQAEARQIADLADSDLTEEERNPQFLRDKGNGFFASGNYQAAVNVYTHALRLN 663

Query: 513 --------NDSSCTEALYNIGLTYKKLNRLDEALD---------SFLKLHAILRNSAQVL 555
                   N ++C   L N+   +K +    +A+D         +  ++ A++R      
Sbjct: 662 PKMPSLYSNRAACHLKLRNL---FKCIEDCSKAMDLLSPPVPQNAASRVKAMVRRGT-AF 495

Query: 556 CQIANIYELMED 567
           CQ+    E ++D
Sbjct: 494 CQLEMYVEGLQD 459
>28154
          Length = 374

 Score = 35.0 bits (79), Expect = 0.11,   Method: Compositional matrix adjust.
 Identities = 17/86 (19%), Positives = 45/86 (52%), Gaps = 1/86 (1%)
 Frame = +1

Query: 234 LKVNMGNIYLKQRNYSKAIKFYRMALDQIPSVHKEMRIKIMQNIGITFIKTGQYSDAINS 293
           ++ N+G ++     Y+KA+  ++ AL   P         +   +G T    G+  +A+++
Sbjct: 100 VQCNLGVLFNLSGEYNKAVDCFQAALQARPK-----DALLWNKLGATLANGGRSEEAVDA 264

Query: 294 FEHIMSMAPS-LKAGFNLILSCFAIG 318
           + + + ++P  +++ +NL ++C  +G
Sbjct: 265 YHNALQLSPGFIRSRYNLGIACINLG 342
>18279
          Length = 706

 Score = 30.0 bits (66), Expect = 3.6,   Method: Compositional matrix adjust.
 Identities = 18/62 (29%), Positives = 28/62 (45%)
 Frame = +3

Query: 501 EKAAEFYKEALRNDSSCTEALYNIGLTYKKLNRLDEALDSFLKLHAILRNSAQVLCQIAN 560
           ++A   YK+ LRND     A   IG        ++E+ D F ++     +   V   IA+
Sbjct: 261 DRALAMYKQVLRNDPKNIWAANGIGCVLAHKGCINESRDVFAQVREATADFCDVWLNIAH 440

Query: 561 IY 562
           IY
Sbjct: 441 IY 446
>10994
          Length = 2182

 Score = 30.0 bits (66), Expect = 3.7,   Method: Compositional matrix adjust.
 Identities = 30/97 (30%), Positives = 44/97 (45%), Gaps = 10/97 (10%)
 Frame = -3

Query: 599  EGDKSQAFQYYYESYRYFPSNIEVIEWLGAYYIDTQFCEKAIQYFERASLIQPTQV--KW 656
            +G   +A Q+   + +  P + E +   GA Y +     KAI+ FE+A    P  V  K 
Sbjct: 1616 KGQHLEAIQHLNLALKIDPLHTEALVARGAVYANNASYGKAIEDFEKALEGDPKHVNAKK 1437

Query: 657  QLM---VASCFR--RSGNYQKALDTYK---EIHRKFP 685
             LM   +AS  R    GN  +A++ YK   E  R  P
Sbjct: 1436 YLMETKIASARRYEEEGNIXEAINNYKSRTEARRSVP 1326
>03857
          Length = 1696

 Score = 30.0 bits (66), Expect = 4.0,   Method: Compositional matrix adjust.
 Identities = 30/129 (23%), Positives = 55/129 (42%)
 Frame = +1

Query: 491 GNTVFANGDYEKAAEFYKEALRNDSSCTEALYNIGLTYKKLNRLDEALDSFLKLHAILRN 550
           GNT+F  G +  A   YK+ALR        L  +    K      +A++   +LH  +  
Sbjct: 484 GNTLFKAGKFGPANRKYKKALR-------YLQKLDEEQKMSEDQQKAMEK--ELHIPVSL 636

Query: 551 SAQVLCQIANIYELMEDPNQAIEWLMQLISVVPTDSQALSKLGELYDSEGDKSQAFQYYY 610
           +A   C   N Y      N+A+E+  +++   P +S+A  + G+ +    D   A   + 
Sbjct: 637 NAAACCLKLNKY------NEALEYCQEVLEADPDNSKAQYRQGQAHAGNKDYETALASFQ 798

Query: 611 ESYRYFPSN 619
           ++    P +
Sbjct: 799 KALAANPDD 825
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|9910452|ref|NP_064304.1| MAPK scaffold protein 1 [Mus
musculus]
         (124 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

37514                                                                  38   9e-04
07595                                                                  30   0.32 
29091                                                                  27   1.5  
05353                                                                  27   1.6  
09699                                                                  26   4.2  
24402                                                                  26   4.8  
>37514
          Length = 89

 Score = 38.1 bits (87), Expect = 9e-04,   Method: Compositional matrix adjust.
 Identities = 17/29 (58%), Positives = 21/29 (72%)
 Frame = +1

Query: 42 EHALRPGFLSTFALATDQGSKLGLSKNKS 70
          E ALRP +LSTF+   DQ SKLG+  N+S
Sbjct: 1  ELALRPAYLSTFSPMVDQASKLGMGNNQS 87
>07595
          Length = 895

 Score = 29.6 bits (65), Expect = 0.32,   Method: Compositional matrix adjust.
 Identities = 18/55 (32%), Positives = 24/55 (43%), Gaps = 4/55 (7%)
 Frame = +2

Query: 64  GLSKN-KSIICYYNTYQVVQFNRLPLVVS---FIASSSANTGLIVSLEKELAPLF 114
           G S N  SI+CY+NT     F+  PL       I S S    +   L+    P+F
Sbjct: 35  GYSHNYTSILCYFNTTHATPFHSTPLTSKTL*TINSHSTQKHMHTHLKTSKRPIF 199
>29091
          Length = 929

 Score = 27.3 bits (59), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 13/33 (39%), Positives = 22/33 (66%), Gaps = 1/33 (3%)
 Frame = +3

Query: 67  KNKSIICY-YNTYQVVQFNRLPLVVSFIASSSA 98
           K++ I+C+   T+Q+V  NRL LV++F  + S 
Sbjct: 489 KSRPILCF*ITTFQLVITNRLDLVITFFNNGST 587
>05353
          Length = 1689

 Score = 27.3 bits (59), Expect = 1.6,   Method: Composition-based stats.
 Identities = 13/28 (46%), Positives = 17/28 (60%)
 Frame = -2

Query: 64  GLSKNKSIICYYNTYQVVQFNRLPLVVS 91
           G SK  +  C + TYQ  + +RLPL VS
Sbjct: 776 GRSKQCNNTCLFTTYQFPKGDRLPLRVS 693
>09699
          Length = 1963

 Score = 25.8 bits (55), Expect = 4.2,   Method: Compositional matrix adjust.
 Identities = 9/14 (64%), Positives = 12/14 (85%)
 Frame = +2

Query: 63   LGLSKNKSIICYYN 76
            LGL+ N SI+C+YN
Sbjct: 1454 LGLTNNSSIVCHYN 1495
>24402
          Length = 1153

 Score = 25.8 bits (55), Expect = 4.8,   Method: Composition-based stats.
 Identities = 9/14 (64%), Positives = 12/14 (85%)
 Frame = -3

Query: 63  LGLSKNKSIICYYN 76
           LGL+ N SI+C+YN
Sbjct: 620 LGLTNNSSIVCHYN 579
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|158749640|ref|NP_057912.2| prolactin regulatory
element binding protein [Mus musculus]
         (417 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

00561                                                                  41   0.001
15337                                                                  38   0.008
36111                                                                  38   0.010
33180                                                                  35   0.050
15780                                                                  35   0.080
14500                                                                  33   0.18 
11915                                                                  32   0.46 
16199                                                                  32   0.53 
13486                                                                  32   0.58 
03156                                                                  31   0.97 
02090                                                                  31   1.0  
19140                                                                  31   1.1  
01327                                                                  31   1.2  
19949                                                                  30   1.4  
13335                                                                  30   1.9  
02715                                                                  30   1.9  
27681                                                                  30   2.5  
27270                                                                  30   2.7  
21785                                                                  29   4.2  
27465                                                                  28   5.0  
03387                                                                  28   6.1  
02147                                                                  28   7.8  
03395                                                                  28   9.3  
>00561
          Length = 1003

 Score = 40.8 bits (94), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 27/91 (29%), Positives = 44/91 (48%), Gaps = 3/91 (3%)
 Frame = -3

Query: 163 NHDNTLLATGGTDGHVRVWKVPSLEKVLEFKAHEGEIGDLTLGPDGKLVTVGW-DFKASV 221
           NH N ++ + G D  V+VW + + +       H G +  +T+ PDG L T G  D KA +
Sbjct: 578 NHSNPIIVSCGWDRTVKVWNLANCKLKNNHHGHNGYLNTVTVSPDGSLCTSGGKDSKALL 399

Query: 222 WQKD--QLVTQLQWQENGPASSNTPYRYQAC 250
           W  +  + +  L+  +   A   +P RY  C
Sbjct: 398 WDLNDGKNLYTLEHNDIINALCFSPNRYWLC 306
>15337
          Length = 860

 Score = 37.7 bits (86), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 22/56 (39%), Positives = 32/56 (57%), Gaps = 1/56 (1%)
 Frame = -1

Query: 169 LATGGTDGHVRVWKVPSLEKVLEFKAHEGEIGDLTLGPDGK-LVTVGWDFKASVWQ 223
           LA  G DGH+RV+   S+E +   K++ G +  +   PDGK +VT G D   +VW 
Sbjct: 284 LAVVGQDGHLRVFNYNSMELIGTMKSYFGGLLCVCWSPDGKYIVTGGEDDLVTVWS 117
>36111
          Length = 687

 Score = 37.7 bits (86), Expect = 0.010,   Method: Compositional matrix adjust.
 Identities = 19/73 (26%), Positives = 34/73 (46%)
 Frame = +2

Query: 155 PLQKVVCFNHDNTLLATGGTDGHVRVWKVPSLEKVLEFKAHEGEIGDLTLGPDGKLVTVG 214
           P+  V   N  NT  ATGG+DG+V +W     +++  F  +   I  L    DG ++ + 
Sbjct: 236 PVNAVAFHNVYNTF-ATGGSDGYVNIWDGFHKKRLCXFHRYPTSIASLAFSHDGNVLAIA 412

Query: 215 WDFKASVWQKDQL 227
             +     ++D +
Sbjct: 413 SSYMYEQEEQDNI 451
>33180
          Length = 460

 Score = 35.0 bits (79), Expect = 0.050,   Method: Compositional matrix adjust.
 Identities = 19/68 (27%), Positives = 32/68 (47%), Gaps = 2/68 (2%)
 Frame = -2

Query: 162 FNHDNTLLATGGTDGHVRVWKVPSLEKVLEFKAHEGEIGDLTLGPDGK--LVTVGWDFKA 219
           F+ DNT +  G  DG + V+   S ++ L+  AH+ ++  +    D    L + G D   
Sbjct: 429 FSSDNTEIVGGANDGCLYVYDRESNQRTLKIDAHDDDVNAVAFADDSSQILYSGGDDGLC 250

Query: 220 SVWQKDQL 227
            VW +  L
Sbjct: 249 KVWDRRTL 226
>15780
          Length = 735

 Score = 34.7 bits (78), Expect = 0.080,   Method: Compositional matrix adjust.
 Identities = 14/32 (43%), Positives = 22/32 (68%)
 Frame = -1

Query: 160 VCFNHDNTLLATGGTDGHVRVWKVPSLEKVLE 191
           +CF+ D T+LA+GG D  +R+W    L +V+E
Sbjct: 630 LCFSRDGTVLASGGMDNSIRLWD---LARVME 544
>14500
          Length = 1238

 Score = 33.5 bits (75), Expect = 0.18,   Method: Compositional matrix adjust.
 Identities = 16/68 (23%), Positives = 30/68 (44%), Gaps = 5/68 (7%)
 Frame = +3

Query: 149 TDFSNEPLQKVVCF-----NHDNTLLATGGTDGHVRVWKVPSLEKVLEFKAHEGEIGDLT 203
           T+ S+   +  VC       H   + + G     + +WK P++ +V E   H   +  + 
Sbjct: 309 TNLSSVDTKSQVCALLWSKEHRELISSHGFAQNQLIIWKYPAMSRVAELTGHTARVLHMA 488

Query: 204 LGPDGKLV 211
           + PDG+ V
Sbjct: 489 MSPDGETV 512
>11915
          Length = 737

 Score = 32.0 bits (71), Expect = 0.46,   Method: Compositional matrix adjust.
 Identities = 15/60 (25%), Positives = 29/60 (48%), Gaps = 2/60 (3%)
 Frame = +1

Query: 168 LLATGGTDGHVRVWKVPSLEKVLEFKAHEGEIGDLTLGPDGK--LVTVGWDFKASVWQKD 225
           +LATG   G +++W   + + ++E   H+  + DL    D    L++   D    +W+ D
Sbjct: 448 VLATGHVSGRIKLWNCETGKLLIEMMDHKATVHDLHFAADNSLCLMSASHDGTVKLWEFD 627
>16199
          Length = 694

 Score = 32.0 bits (71), Expect = 0.53,   Method: Compositional matrix adjust.
 Identities = 11/43 (25%), Positives = 22/43 (51%)
 Frame = +2

Query: 162 FNHDNTLLATGGTDGHVRVWKVPSLEKVLEFKAHEGEIGDLTL 204
           F+ D  + ATG  D  +++W +     V  F+ H+G +  ++ 
Sbjct: 95  FHPDGLIFATGTEDSVIKIWDLKERANVANFQGHQGPVTSISF 223

 Score = 30.0 bits (66), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 18/72 (25%), Positives = 32/72 (44%)
 Frame = +1

Query: 140 KVKNLEAVQTDFSNEPLQKVVCFNHDNTLLATGGTDGHVRVWKVPSLEKVLEFKAHEGEI 199
           K+KN + +Q    ++   K +CF+   T LA  G+D  VRV+      ++  F  H    
Sbjct: 289 KLKNFKTLQ--LGDKYEVKALCFDQSGTYLAVAGSD--VRVYLCKQWNELAVFNDHTATA 456

Query: 200 GDLTLGPDGKLV 211
             +  G +   +
Sbjct: 457 TGVRFGTNANFI 492
>13486
          Length = 1509

 Score = 31.6 bits (70), Expect = 0.58,   Method: Compositional matrix adjust.
 Identities = 15/36 (41%), Positives = 20/36 (55%)
 Frame = -1

Query: 160 VCFNHDNTLLATGGTDGHVRVWKVPSLEKVLEFKAH 195
           VCFN D +LLA+    G V +WK    + +L F  H
Sbjct: 882 VCFNCDESLLASCDAQGMVIIWKREGKQGIL*FVHH 775
>03156
          Length = 1014

 Score = 30.8 bits (68), Expect = 0.97,   Method: Compositional matrix adjust.
 Identities = 13/43 (30%), Positives = 23/43 (53%)
 Frame = +1

Query: 143 NLEAVQTDFSNEPLQKVVCFNHDNTLLATGGTDGHVRVWKVPS 185
           N  +++    ++ +   +  N DNTLL +G  D  VR+W V +
Sbjct: 148 NSHSIRDFIGHDMVVTAIHLNTDNTLLCSGSRDNTVRIWDVET 276
>02090
          Length = 1841

 Score = 30.8 bits (68), Expect = 1.0,   Method: Compositional matrix adjust.
 Identities = 19/72 (26%), Positives = 33/72 (45%), Gaps = 1/72 (1%)
 Frame = -3

Query: 152  SNEPLQKVVCFNHDNTLLATGGTDGHVRVWKVPSLEKVLEFKAHEGEIGDLTLGPDG-KL 210
            S+ P    +  + D  +  +  +DG++ VW + +   V +F+ H      + + PDG KL
Sbjct: 1632 SSAPACYALAISPDGKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISPDGTKL 1453

Query: 211  VTVGWDFKASVW 222
             T G D     W
Sbjct: 1452 WTGGLDNTVRSW 1417
>19140
          Length = 573

 Score = 30.8 bits (68), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 12/39 (30%), Positives = 20/39 (51%)
 Frame = -3

Query: 158 KVVCFNHDNTLLATGGTDGHVRVWKVPSLEKVLEFKAHE 196
           K +  N D T   +G +DG +R+W +     V  F+ H+
Sbjct: 475 KALVLNRDGTQCLSGSSDGTIRLWSLGQQRCVATFRVHD 359
>01327
          Length = 2215

 Score = 30.8 bits (68), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 13/43 (30%), Positives = 23/43 (53%)
 Frame = +3

Query: 143 NLEAVQTDFSNEPLQKVVCFNHDNTLLATGGTDGHVRVWKVPS 185
           N  +++    ++ +   +  N DNTLL +G  D  VR+W V +
Sbjct: 258 NSHSIRDFIGHDMVVTAIHLNTDNTLLCSGSRDNTVRIWDVET 386
>19949
          Length = 903

 Score = 30.4 bits (67), Expect = 1.4,   Method: Compositional matrix adjust.
 Identities = 18/71 (25%), Positives = 31/71 (43%), Gaps = 8/71 (11%)
 Frame = +2

Query: 170 ATGGTDGHVRVWKVPSLEKVLEFKAHEGEIGDLTLGPDGKLVTVG--------WDFKASV 221
           A+G  D +V++W +     +  +K H G +  L   PDG+ +           WD  A  
Sbjct: 41  ASGSMDCNVKLWDIRRKGCIYTYKGHTGCVCCLRFSPDGRWIASASEDGLVKLWDLTAG- 217

Query: 222 WQKDQLVTQLQ 232
               +L+T L+
Sbjct: 218 ----KLLTDLK 238
>13335
          Length = 863

 Score = 30.0 bits (66), Expect = 1.9,   Method: Compositional matrix adjust.
 Identities = 14/57 (24%), Positives = 28/57 (49%)
 Frame = +1

Query: 158 KVVCFNHDNTLLATGGTDGHVRVWKVPSLEKVLEFKAHEGEIGDLTLGPDGKLVTVG 214
           +V  F+  ++ L +G  D  + +W+V + + V  +  HE  +  L   P+G  +  G
Sbjct: 73  RVCKFSPSSSHLVSGSDDDTICMWEVATQKLVRSYVGHEDSVMALAYSPNGHYLVSG 243

 Score = 28.9 bits (63), Expect = 4.5,   Method: Compositional matrix adjust.
 Identities = 15/50 (30%), Positives = 26/50 (52%), Gaps = 2/50 (4%)
 Frame = +1

Query: 143 NLEAVQTDFSNEPLQKVVC--FNHDNTLLATGGTDGHVRVWKVPSLEKVL 190
           ++EA  + F       V C  F+ D TLLA+G  D  +++WK+     ++
Sbjct: 619 SIEACHSRF-------VTCCAFSIDGTLLASGSMDRIIKIWKLTDTSSIM 747
>02715
          Length = 1239

 Score = 30.0 bits (66), Expect = 1.9,   Method: Compositional matrix adjust.
 Identities = 19/72 (26%), Positives = 30/72 (41%), Gaps = 8/72 (11%)
 Frame = -1

Query: 252 FGQVPDQLGGLR-------LFTVQIPHKRLRQPPPCYLTAWDSSTFLPLRTR-SCGHEVI 303
           F + P+    L+       LF +        + P  Y +  + S   P+  R SCGH+ +
Sbjct: 933 FNEEPEHTNSLQTMMATASLFNIIFKSHFFNKNPQIYCSRTEVSVCXPVFVRVSCGHDFL 754

Query: 304 SCLSVSDSGTFL 315
            CL    S T+L
Sbjct: 753 RCLGADHSQTWL 718
>27681
          Length = 465

 Score = 29.6 bits (65), Expect = 2.5,   Method: Compositional matrix adjust.
 Identities = 11/22 (50%), Positives = 16/22 (72%)
 Frame = +2

Query: 162 FNHDNTLLATGGTDGHVRVWKV 183
           +N + TLLATG  DG+ R+W+ 
Sbjct: 185 WNSEGTLLATGSYDGYARLWRT 250

 Score = 29.6 bits (65), Expect = 2.7,   Method: Compositional matrix adjust.
 Identities = 24/95 (25%), Positives = 39/95 (41%), Gaps = 15/95 (15%)
 Frame = +2

Query: 159 VVCFNHDNTLLATGGTDGHVRVWKVPSL------EKVLEFKAHEG--------EIGDLTL 204
           +  +N  N LLA+G  D   R+W + S       + VL     +G        ++  L  
Sbjct: 8   ICAWNPTNDLLASGSGDSTARIWNMTSETPNNANQLVLRHCIQKGGTEVPSNKDVTSLDW 187

Query: 205 GPDGKLVTVG-WDFKASVWQKDQLVTQLQWQENGP 238
             +G L+  G +D  A +W+ D  +     Q  GP
Sbjct: 188 NSEGTLLATGSYDGYARLWRTDGHLVNTLGQHKGP 292
>27270
          Length = 1078

 Score = 29.6 bits (65), Expect = 2.7,   Method: Compositional matrix adjust.
 Identities = 13/38 (34%), Positives = 20/38 (52%)
 Frame = +2

Query: 160 VCFNHDNTLLATGGTDGHVRVWKVPSLEKVLEFKAHEG 197
           +C+  D   L +   DGHV  W V +L  + ++KA  G
Sbjct: 290 MCWRADGRTLYSSSLDGHVIGWNVNTLHMIEKWKATSG 403
>21785
          Length = 958

 Score = 28.9 bits (63), Expect = 4.2,   Method: Compositional matrix adjust.
 Identities = 15/31 (48%), Positives = 19/31 (61%)
 Frame = +2

Query: 267 VQIPHKRLRQPPPCYLTAWDSSTFLPLRTRS 297
           VQ PH   ++ PPC+ T W   T L L+TRS
Sbjct: 482 VQFPH--CQRQPPCWRTLWPCRTLLVLQTRS 568
>27465
          Length = 658

 Score = 28.5 bits (62), Expect = 5.0,   Method: Compositional matrix adjust.
 Identities = 13/33 (39%), Positives = 20/33 (60%), Gaps = 2/33 (6%)
 Frame = -1

Query: 158 KVVC--FNHDNTLLATGGTDGHVRVWKVPSLEK 188
           ++VC  FN  +TL+ATG  D   R+W V   ++
Sbjct: 100 EIVCVSFNPSSTLIATGSMDTTCRLWDVEKAQR 2
>03387
          Length = 1891

 Score = 28.1 bits (61), Expect = 6.1,   Method: Compositional matrix adjust.
 Identities = 19/76 (25%), Positives = 31/76 (40%), Gaps = 16/76 (21%)
 Frame = +1

Query: 164 HDNTLLATGGTDGHVRVWKVPSL--------------EKVLEFKAHEGEIGDLTLGPDGK 209
           H+ T+LA+ GTD  + VW +  +              E +     H  +I D +  P+  
Sbjct: 814 HNETILASSGTDRRLHVWDLSKIGEEQLPEDAEDGPPELLFIHGGHTAKISDFSWNPNEP 993

Query: 210 LV--TVGWDFKASVWQ 223
            +  +V  D    VWQ
Sbjct: 994 WIVCSVSEDNIMQVWQ 1041
>02147
          Length = 1547

 Score = 28.1 bits (61), Expect = 7.8,   Method: Compositional matrix adjust.
 Identities = 23/95 (24%), Positives = 41/95 (43%)
 Frame = +2

Query: 158 KVVCFNHDNTLLATGGTDGHVRVWKVPSLEKVLEFKAHEGEIGDLTLGPDGKLVTVGWDF 217
           K   F  D   + +   D  VR+W + + ++V +    +     LTL PD   + V    
Sbjct: 437 KGALFLSDGKRIISASDDKTVRLWSLETCQEVQQL-TFDTPPTSLTLSPDKNTIIVTHSQ 613

Query: 218 KASVWQKDQLVTQLQWQENGPASSNTPYRYQACRF 252
             + +Q D L    +++   P SS +   +Q+ RF
Sbjct: 614 NIAFYQADTLREMKKFEAEAPISSAS--LHQSERF 712
>03395
          Length = 2795

 Score = 27.7 bits (60), Expect = 9.3,   Method: Compositional matrix adjust.
 Identities = 20/75 (26%), Positives = 36/75 (48%), Gaps = 2/75 (2%)
 Frame = +2

Query: 154 EPLQKVVCFNHDNTLLATGGTDGHVRVWKVPSLEKVLEFKAHE-GEIGDLTLGPDGK-LV 211
             L K VCF   +  + T GTD  +  W+V     + E +  + G I  + +  DG+ ++
Sbjct: 269 NTLFKCVCFGGKDLHILTSGTDHKIGYWEVGDGGLLRELEGSQTGAINTIDIDRDGQTIL 448

Query: 212 TVGWDFKASVWQKDQ 226
           T G D    +W+ ++
Sbjct: 449 TGGEDSLLKLWRYNE 493
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|51711902|ref|XP_355752.2| PREDICTED: diacylglycerol
kinase, iota isoform 1 [Mus musculus]
         (1071 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

15772                                                                  42   0.001
13462                                                                  41   0.003
28113                                                                  38   0.019
11295                                                                  38   0.023
28494                                                                  37   0.044
17893                                                                  35   0.13 
06253                                                                  35   0.16 
14005                                                                  35   0.17 
30978                                                                  34   0.29 
19166                                                                  34   0.35 
18156                                                                  33   0.76 
25470                                                                  32   1.2  
04667                                                                  32   1.3  
05924                                                                  32   1.4  
04576                                                                  32   1.4  
22686                                                                  32   1.7  
15785                                                                  31   2.6  
08473                                                                  30   4.7  
09292                                                                  30   5.2  
>15772
          Length = 1282

 Score = 42.0 bits (97), Expect = 0.001,   Method: Composition-based stats.
 Identities = 40/119 (33%), Positives = 59/119 (49%), Gaps = 4/119 (3%)
 Frame = -3

Query: 939  AVLTGDLMKLMESYKNG-GSLLIQGP--GHCSLLHYAAKTGNGDIVKYILDHGPAELLDM 995
            A  TGD   L +  K+G   + ++ P  G+ + LH+A + G  + ++ +LDHG       
Sbjct: 1265 AASTGDYDALEDYVKSGIYDVNLKDPDAGNKTALHWACQKGFVECIRLLLDHGAK---GT 1095

Query: 996  ADSETGETALHKAA-CQRNRAVCQLLVDAGASLRQTDSKGKTPQERAQQAGDPDLAAYL 1053
            A ++TG T  H AA C R  A+ + L  A   +  TD  G TP+  A   G  D A YL
Sbjct: 1094 ARTDTGWTPAHCAAECNRVTAL-RALHAALVPVDLTDKYGDTPRRIATLYGHRDCARYL 921
>13462
          Length = 1388

 Score = 40.8 bits (94), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 30/87 (34%), Positives = 41/87 (47%), Gaps = 2/87 (2%)
 Frame = +3

Query: 969  LHYAAKTGNGD--IVKYILDHGPAELLDMADSETGETALHKAACQRNRAVCQLLVDAGAS 1026
            LHYA+   NG+  IV  +L +G          E G TALH A  + N  V +LL++ G  
Sbjct: 189  LHYASHHSNGNLGIVSMLLAYGAQP---NVQDEDGNTALHLACSESNVDVVRLLLEWGGD 359

Query: 1027 LRQTDSKGKTPQERAQQAGDPDLAAYL 1053
            +   D   +TP  RA  A   +L   L
Sbjct: 360  VAVADIDNETPLVRACLANSVELVDLL 440
>28113
          Length = 449

 Score = 38.1 bits (87), Expect = 0.019,   Method: Compositional matrix adjust.
 Identities = 27/85 (31%), Positives = 43/85 (50%)
 Frame = -3

Query: 969  LHYAAKTGNGDIVKYILDHGPAELLDMADSETGETALHKAACQRNRAVCQLLVDAGASLR 1028
            LH +A  G+   V+ +L+HG               A+H A+   +  V ++L+DAG S  
Sbjct: 321  LHASAAQGDVHHVQSLLNHGHHH---SKKDSIAWAAIHYASWYGSADVVEILLDAGCSPN 151

Query: 1029 QTDSKGKTPQERAQQAGDPDLAAYL 1053
             T+S+  TP   A + G PD+A +L
Sbjct: 150  LTNSELLTPLHIAAKKGFPDVAEHL 76
>11295
          Length = 1179

 Score = 37.7 bits (86), Expect = 0.023,   Method: Compositional matrix adjust.
 Identities = 28/96 (29%), Positives = 42/96 (43%), Gaps = 1/96 (1%)
 Frame = +1

Query: 967  SLLHYAAKTGNGDIVKYILDHGPAELLDM-ADSETGETALHKAACQRNRAVCQLLVDAGA 1025
            S LH+A    N ++ + +LD    + + + A S    TALH A C  +R +  LL+  GA
Sbjct: 70   SALHHACIGRNTEVAELLLDGWNGDGIAVNATSNDHVTALHIACCLDDREMASLLLKYGA 249

Query: 1026 SLRQTDSKGKTPQERAQQAGDPDLAAYLESRQNYKI 1061
                 D  G TP   A   G   +   L  R +  +
Sbjct: 250  YAMALDVIGHTPLHVACWCGSEGVTRLLLDRSDVDV 357
>28494
          Length = 463

 Score = 37.0 bits (84), Expect = 0.044,   Method: Compositional matrix adjust.
 Identities = 26/82 (31%), Positives = 43/82 (52%)
 Frame = -1

Query: 972  AAKTGNGDIVKYILDHGPAELLDMADSETGETALHKAACQRNRAVCQLLVDAGASLRQTD 1031
            A  +G+ D VK +L+ G    ++ A+ + G TALH+A    N  + + LV+  A +   D
Sbjct: 298  ACSSGDRDEVKKLLERGAD--INTANVD-GLTALHQACIDDNLDMVEFLVEQNADVDVCD 128

Query: 1032 SKGKTPQERAQQAGDPDLAAYL 1053
            ++G TP       G  ++A YL
Sbjct: 127  NEGWTPLHATASCGFTEIARYL 62
>17893
          Length = 453

 Score = 35.4 bits (80), Expect = 0.13,   Method: Composition-based stats.
 Identities = 22/54 (40%), Positives = 31/54 (57%)
 Frame = -3

Query: 953  KNGGSLLIQGPGHCSLLHYAAKTGNGDIVKYILDHGPAELLDMADSETGETALH 1006
            KNG S+ I      +LLH AA+  + D+ +++LDHG    +D  D   G TALH
Sbjct: 157  KNGASINIMDRTGQTLLHEAARAWHVDVTRWLLDHGIN--IDQPDY-YGRTALH 5

 Score = 32.0 bits (71), Expect = 1.5,   Method: Composition-based stats.
 Identities = 24/67 (35%), Positives = 38/67 (56%)
 Frame = -3

Query: 970  HYAAKTGNGDIVKYILDHGPAELLDMADSETGETALHKAACQRNRAVCQLLVDAGASLRQ 1029
            H  AK  N D V  +L +G +  +++ D  TG+T LH+AA   +  V + L+D G ++ Q
Sbjct: 202  HEEAKI-NLDFVDSLLKNGAS--INIMD-RTGQTLLHEAARAWHVDVTRWLLDHGINIDQ 35

Query: 1030 TDSKGKT 1036
             D  G+T
Sbjct: 34   PDYYGRT 14
>06253
          Length = 1049

 Score = 35.0 bits (79), Expect = 0.16,   Method: Compositional matrix adjust.
 Identities = 27/85 (31%), Positives = 39/85 (45%)
 Frame = -1

Query: 969  LHYAAKTGNGDIVKYILDHGPAELLDMADSETGETALHKAACQRNRAVCQLLVDAGASLR 1028
            LH+AA  G  D+V+++L++G       A  + G   LH A    +  V QLL+  GA   
Sbjct: 1034 LHFAAGFGRKDVVEHLLENGANV---HARDDGGLIPLHNACSFGHAEVVQLLLRHGADPN 864

Query: 1029 QTDSKGKTPQERAQQAGDPDLAAYL 1053
              D+   TP   A   G  D+   L
Sbjct: 863  ARDNWNYTPLHEAAIKGKIDVCIVL 789

 Score = 30.0 bits (66), Expect = 5.0,   Method: Compositional matrix adjust.
 Identities = 25/83 (30%), Positives = 40/83 (48%), Gaps = 2/83 (2%)
 Frame = -1

Query: 953  KNGGSLLIQGPGHCSLLHYAAKTGNGDIVKYILDHGPAELLDMADSETGETALHKAACQR 1012
            +NG ++  +  G    LH A   G+ ++V+ +L HG       A      T LH+AA + 
Sbjct: 983  ENGANVHARDDGGLIPLHNACSFGHAEVVQLLLRHGADP---NARDNWNYTPLHEAAIKG 813

Query: 1013 NRAVCQLLVD--AGASLRQTDSK 1033
               VC +L+   A  ++R TD K
Sbjct: 812  KIDVCIVLLQQCADPNIRNTDGK 744
>14005
          Length = 1745

 Score = 35.0 bits (79), Expect = 0.17,   Method: Compositional matrix adjust.
 Identities = 27/78 (34%), Positives = 41/78 (52%)
 Frame = -1

Query: 964  GHCSLLHYAAKTGNGDIVKYILDHGPAELLDMADSETGETALHKAACQRNRAVCQLLVDA 1023
            GH + LH A+  G    V Y+LD   AE+   A +  G  ALH A   ++  + +LL+  
Sbjct: 1241 GH-TALHVASVRGFKQHVIYLLDFCDAEV--NAATLKGNNALHIACRGKHADLVELLLHK 1071

Query: 1024 GASLRQTDSKGKTPQERA 1041
            GA+  Q + +G TP+  A
Sbjct: 1070 GANPAQRNQRGWTPRNSA 1017
>30978
          Length = 566

 Score = 34.3 bits (77), Expect = 0.29,   Method: Compositional matrix adjust.
 Identities = 24/85 (28%), Positives = 45/85 (52%)
 Frame = -2

Query: 969  LHYAAKTGNGDIVKYILDHGPAELLDMADSETGETALHKAACQRNRAVCQLLVDAGASLR 1028
            LH+A   G+ D ++ +L     E+     ++ G+TALH AA + +    ++L+  GA + 
Sbjct: 460  LHWAGHGGHMDCLQVLLSEPKCEV--NVQNKLGDTALHSAAWKNHVEAVKMLLGKGARVD 287

Query: 1029 QTDSKGKTPQERAQQAGDPDLAAYL 1053
              +++ K   E  +   DP++AA L
Sbjct: 286  LRNNEKKLAVELTK---DPEVAAML 221
>19166
          Length = 447

 Score = 33.9 bits (76), Expect = 0.35,   Method: Compositional matrix adjust.
 Identities = 27/98 (27%), Positives = 47/98 (47%), Gaps = 2/98 (2%)
 Frame = +1

Query: 953  KNGGSLLIQGPGHCSLLHYAAKTGNGDIVKYILDHGPAELLDMADSET--GETALHKAAC 1010
            K G S+        + LH ++  G+ +IV Y++ H         D+ T  GET+LH AA 
Sbjct: 121  KYGASIDATTESGLTPLHVSSFMGHMNIVIYLIQHNA-----YPDTPTVRGETSLHLAAR 285

Query: 1011 QRNRAVCQLLVDAGASLRQTDSKGKTPQERAQQAGDPD 1048
                 + ++L+  GA++     + +TP   A + G+ D
Sbjct: 286  ANQTDIIRILLRNGAAVDARAREQQTPLHIASRLGNVD 399
>18156
          Length = 421

 Score = 32.7 bits (73), Expect = 0.76,   Method: Compositional matrix adjust.
 Identities = 21/57 (36%), Positives = 33/57 (57%), Gaps = 3/57 (5%)
 Frame = -2

Query: 424 ILACGGDGTVGWILSIL---DELQLSPQPPVGVLPLGTGNDLARTLNWGGGYTDEPV 477
           I+   GDG V  +++ L   ++   + + P+G LP G+GN LA +LN+  G   EPV
Sbjct: 282 IIIVSGDGLVYEVINGLMHREDWTSAIKKPLGCLPGGSGNALACSLNYAAG---EPV 121
>25470
          Length = 400

 Score = 32.3 bits (72), Expect = 1.2,   Method: Composition-based stats.
 Identities = 25/83 (30%), Positives = 40/83 (48%), Gaps = 2/83 (2%)
 Frame = -3

Query: 953  KNGGSLLIQGPGHCSLLHYAAKTGNGDIVKYILDHGPAELLDMADSETGETALHKAACQR 1012
            +NG ++  +  G    LH A   G+ ++V+ +L HG       A      T LH+AA + 
Sbjct: 335  ENGANVHARDDGGLIPLHNACSFGHAEVVQLLLRHGADP---NARDNWNYTPLHEAAIKG 165

Query: 1013 NRAVCQLLVD--AGASLRQTDSK 1033
               VC +L+   A  ++R TD K
Sbjct: 164  KIDVCIVLLQQCADPNIRNTDGK 96
>04667
          Length = 1874

 Score = 32.0 bits (71), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 35/117 (29%), Positives = 53/117 (45%), Gaps = 23/117 (19%)
 Frame = -1

Query: 370  KPLLVFVNPKSGGNQGT-----KVLQMFMWYLNPRQVFDLS--QEGPKDALEM-YRKVPN 421
            K + VF+ P +G   G      KVL +F    N     DL+  Q       EM +  V +
Sbjct: 1703 KNVKVFLQPYAGDKNGRSIYKHKVLSIFQ---NAGVAADLTVIQHNEHVKQEMIHLNVYD 1533

Query: 422  LR-ILACGGDGTVGWILSIL---------DELQLSPQP-----PVGVLPLGTGNDLA 463
               ++A GGDGTV  +L+ L          EL++   P     P+G++P+G  N +A
Sbjct: 1532 FDCVIAMGGDGTVHQVLNGLMQRSQKENETELKVGTNPARALVPMGIIPIGKTNQIA 1362
>05924
          Length = 704

 Score = 32.0 bits (71), Expect = 1.4,   Method: Composition-based stats.
 Identities = 20/70 (28%), Positives = 34/70 (48%)
 Frame = +1

Query: 967  SLLHYAAKTGNGDIVKYILDHGPAELLDMADSETGETALHKAACQRNRAVCQLLVDAGAS 1026
            +LLH A    + D+V+ ++  G       + ++ G TALH A       + Q+L+ AG  
Sbjct: 70   TLLHEAVSMASEDLVQMLIKAGANA---NSTNQDGRTALHLACRGGYTNIVQILIAAGTD 240

Query: 1027 LRQTDSKGKT 1036
            + +    GKT
Sbjct: 241  VNRRTVDGKT 270

 Score = 29.6 bits (65), Expect = 6.3,   Method: Composition-based stats.
 Identities = 15/51 (29%), Positives = 26/51 (50%)
 Frame = +1

Query: 1003 TALHKAACQRNRAVCQLLVDAGASLRQTDSKGKTPQERAQQAGDPDLAAYL 1053
            T LH+A    +  + Q+L+ AGA+   T+  G+T    A + G  ++   L
Sbjct: 70   TLLHEAVSMASEDLVQMLIKAGANANSTNQDGRTALHLACRGGYTNIVQIL 222
>04576
          Length = 1310

 Score = 32.0 bits (71), Expect = 1.4,   Method: Composition-based stats.
 Identities = 26/72 (36%), Positives = 30/72 (41%), Gaps = 1/72 (1%)
 Frame = +2

Query: 144 HPLGLP-VANGPAKEPRATLDWSENAVNGEHLWLETNVSGDLCYLGEENCQVRFAKSALR 202
           H L  P V  G A+E    L W E   +GE+  LET         G E C V F     R
Sbjct: 101 HSLVHPGVTPGGAEETVPGLSWHEGKQHGEYSLLETEKGFLDMTTGTERCVVHFFHPDFR 280

Query: 203 RKCAVCKIVVHT 214
           R CAV    + T
Sbjct: 281 R-CAVVDTHLQT 313
>22686
          Length = 934

 Score = 31.6 bits (70), Expect = 1.7,   Method: Composition-based stats.
 Identities = 16/46 (34%), Positives = 21/46 (45%)
 Frame = -2

Query: 504 DLPPEELEDGVCKLPLNVFNNYFSLGFDAHVTLEFHESREANPEKF 549
           +LP   LE  +CK+     NNYFS     +  L+FH      P  F
Sbjct: 867 ELPLHTLEVILCKVKFGYSNNYFSSAISTNYMLQFHTMYLVLPRLF 730
>15785
          Length = 402

 Score = 31.2 bits (69), Expect = 2.6,   Method: Compositional matrix adjust.
 Identities = 13/38 (34%), Positives = 19/38 (50%)
 Frame = +3

Query: 814 PRALSAQRLSPRWCFLDATSADRFYRIDRSQEHLHFVM 851
           P  L A R  P WC+ +A  +   Y   R+  H HF++
Sbjct: 9   PLQLVA*RPCPEWCYFEADHSPGSYTHARTHAHTHFIL 122
>08473
          Length = 942

 Score = 30.0 bits (66), Expect = 4.7,   Method: Compositional matrix adjust.
 Identities = 19/56 (33%), Positives = 30/56 (53%)
 Frame = -1

Query: 1001 GETALHKAACQRNRAVCQLLVDAGASLRQTDSKGKTPQERAQQAGDPDLAAYLESR 1056
            G+T L  AA +   ++C+LLVD GA++   D    TP   A + G+ +   +L  R
Sbjct: 819  GKTPLFYAAHRGEISICKLLVDKGANVNAADKMLITPLMVAAREGNREAVEFLLKR 652
>09292
          Length = 1486

 Score = 30.0 bits (66), Expect = 5.2,   Method: Compositional matrix adjust.
 Identities = 22/71 (30%), Positives = 37/71 (52%), Gaps = 2/71 (2%)
 Frame = -2

Query: 969  LHYAAKTGNGDIVKYILDHGPAELLDMADSETG--ETALHKAACQRNRAVCQLLVDAGAS 1026
            LHYA   GN DIV+ +L  G +++    +S  G     LH A  ++   + + L+  GA+
Sbjct: 669  LHYAVIGGNVDIVRLVL-QGSSDV----NSPDGRNNAPLHLACMKQCIGIARCLLRHGAN 505

Query: 1027 LRQTDSKGKTP 1037
            +  +   G+TP
Sbjct: 504  VNVSGYNGRTP 472
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|112363090|ref|NP_032755.2| catenin (cadherin
associated protein), delta 2 [Mus musculus]
         (1246 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

22653                                                                  42   0.002
15086                                                                  33   0.55 
14657                                                                  32   1.2  
06072                                                                  31   3.0  
23481                                                                  30   5.8  
35338                                                                  30   6.7  
18815                                                                  30   8.2  
29099                                                                  30   9.0  
>22653
          Length = 1347

 Score = 42.0 bits (97), Expect = 0.002,   Method: Composition-based stats.
 Identities = 31/100 (31%), Positives = 54/100 (54%), Gaps = 2/100 (2%)
 Frame = +3

Query: 554 MLQHQFPSVQSNAAAYLQHLCFGDNKIKAEIRRQ--GGIQLLVDLLDHRMTEVHRSACGA 611
           +L++Q P VQ+ +AA+    C  + K   E+ R   GG++L+V LL     EV  + C A
Sbjct: 12  LLKNQNPDVQA-SAAWAICPCIENAKDAGEMVRSFVGGLELIVSLLKSEDKEVLAAVCAA 188

Query: 612 LRNLVYGKANDDNKIALKNCGGIPALVRLLRKTTDLEIRE 651
           + N+    A D+  +A+    G+  ++  L  TTD ++R+
Sbjct: 189 IANI----AKDEENLAVITDHGVVPMLAKLTLTTDDKLRQ 296
>15086
          Length = 548

 Score = 33.5 bits (75), Expect = 0.55,   Method: Composition-based stats.
 Identities = 31/101 (30%), Positives = 46/101 (45%), Gaps = 7/101 (6%)
 Frame = +1

Query: 548 LPEVIQMLQHQFPSVQSNAAAYLQHLCFGDNKIKAEIRRQGGI---QLLVDLLDHRMT-- 602
           +PE+I++L  +   V   AA  +  L       K E  R   +   Q++  L+    T  
Sbjct: 4   IPELIKLLSDEDQVVVCQAAMMVHQLS------KKEASRHAIMNSPQMIAALIRALATTD 165

Query: 603 --EVHRSACGALRNLVYGKANDDNKIALKNCGGIPALVRLL 641
             E  R A G L NL + +      +A+   GGIPALV+LL
Sbjct: 166 DMETTRCAAGTLHNLSHHR---QGLLAIFKSGGIPALVKLL 279
>14657
          Length = 918

 Score = 32.3 bits (72), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 46/185 (24%), Positives = 81/185 (43%)
 Frame = -3

Query: 584 IRRQGGIQLLVDLLDHRMTEVHRSACGALRNLVYGKANDDNKIALKNCGGIPALVRLLRK 643
           I + GGI  LV LL   M  V   A   L NL+  +  + +K+A++  GG+  +V LL++
Sbjct: 529 IFKSGGIPALVKLLSSPMESVLFYAITTLHNLLLHQ--EGSKMAVRLAGGLQKMVALLQR 356

Query: 644 TTDLEIRELVTGVLWNLSSCDALKMPIIQDALAVLTNAVIIPHSGWENSPLQDDRKIQLH 703
             +++   + T  L  L+  +               + +II  SG    P +  R ++ +
Sbjct: 355 NNNVKFLAITTDCLQILAYGNQ-------------ESKLIILASG---GPGELVRIMKSY 224

Query: 704 SSQVLRNATGCLRNVSSAGEEARRRMRECDGLTDALLYVIQSALGSSEIDSKTVENCVCI 763
           + + L   T  +  V S     +  + E  G+    ++     LG      + V+NC+  
Sbjct: 223 TYEKLLWTTSRVLKVLSVCPSNKPAIVEAGGMQALAMH-----LGHQ--SQRLVQNCLWS 65

Query: 764 LRNLS 768
           LRNLS
Sbjct: 64  LRNLS 50

 Score = 30.4 bits (67), Expect = 5.2,   Method: Compositional matrix adjust.
 Identities = 28/95 (29%), Positives = 44/95 (46%), Gaps = 1/95 (1%)
 Frame = -3

Query: 548 LPEVIQMLQHQFPSVQSNAAAYLQHLCFGDNKIKAEIRRQGGIQLLVDLL-DHRMTEVHR 606
           +PE+I++L  +   V   AA  +  L   +    A +     I  L+  + +    E  R
Sbjct: 763 IPELIKLLXDEDXVVVYQAAMMVHQLSKKEASRHAIMNSPQMIAALIRAMANTEDIETTR 584

Query: 607 SACGALRNLVYGKANDDNKIALKNCGGIPALVRLL 641
            A G L NL + +      +A+   GGIPALV+LL
Sbjct: 583 CAAGTLHNLSHHR---QGLLAIFKSGGIPALVKLL 488
>06072
          Length = 1397

 Score = 31.2 bits (69), Expect = 3.0,   Method: Compositional matrix adjust.
 Identities = 21/93 (22%), Positives = 39/93 (41%)
 Frame = +1

Query: 551 VIQMLQHQFPSVQSNAAAYLQHLCFGDNKIKAEIRRQGGIQLLVDLLDHRMTEVHRSACG 610
           ++++L H   SV + A   + ++  GD+     I     +  L+ LL      + + AC 
Sbjct: 808 LVELLMHNHQSVVAAALRVVGNIVTGDDSQTQVILSCSALPCLLHLLSSNKETIRKEACW 987

Query: 611 ALRNLVYGKANDDNKIALKNCGGIPALVRLLRK 643
            + N+  G  N    +   N    P L+ +L K
Sbjct: 988 TISNITAGNRNQIQDVIDTNI--FPVLIEILGK 1080
>23481
          Length = 3492

 Score = 30.0 bits (66), Expect = 5.8,   Method: Compositional matrix adjust.
 Identities = 22/61 (36%), Positives = 27/61 (44%)
 Frame = +1

Query: 471  QHGPQNAAAATFQRASYAAGPASNYADPYRQLQYCASVDSPYSKSGPALPPEGTLARSPS 530
            Q  PQN   +   R +       NY  P  +L + ASV S  S+S  ALP  G   R  S
Sbjct: 1852 QISPQNVRNSNCWRFNPGRQSVGNYRRPSVRLHHSASVSSRLSQSN*ALPGGGRRVRLLS 2031

Query: 531  I 531
            I
Sbjct: 2032 I 2034
>35338
          Length = 292

 Score = 30.0 bits (66), Expect = 6.7,   Method: Composition-based stats.
 Identities = 19/71 (26%), Positives = 35/71 (49%), Gaps = 7/71 (9%)
 Frame = +2

Query: 552 IQMLQHQFPSVQSNAAAYLQHLCF-----GDNKIKAEIRRQGGIQLLV-DLLDHRM-TEV 604
           +Q++   F    ++ A   Q L       G +K+K  + +QGG++L+V  ++ H   + +
Sbjct: 80  VQLILQAFEKNLADKAIVRQALVVLRALAGSDKVKVAVVKQGGVELIVASMVKHASNSSI 259

Query: 605 HRSACGALRNL 615
              ACG L  L
Sbjct: 260 AEGACGVLATL 292
>18815
          Length = 1000

 Score = 29.6 bits (65), Expect = 8.2,   Method: Compositional matrix adjust.
 Identities = 13/28 (46%), Positives = 18/28 (64%)
 Frame = +3

Query: 417 DPIYEDRVYQKPPMRSLSQSQGDPLPPA 444
           DP    R++Q+PP+R   Q +GDP  PA
Sbjct: 264 DPDEPGRLHQRPPVRHAGQVRGDPXHPA 347
>29099
          Length = 708

 Score = 29.6 bits (65), Expect = 9.0,   Method: Composition-based stats.
 Identities = 36/131 (27%), Positives = 54/131 (41%), Gaps = 4/131 (3%)
 Frame = +3

Query: 545 DPELPEVIQMLQHQFPSVQSNAAAYLQHLCFGDNKIKAEIRRQGGIQLLVDLLDHRMTEV 604
           D  L  V+Q +      VQ  A   L  L     +I+   R     + LV L+     +V
Sbjct: 162 DKLLENVVQGMNTGDEKVQVAACRCLHSLSRSVQQIRTTFRDHAVWKPLVTLMRSNSDDV 341

Query: 605 HRSACGALRNLVYGKANDDNKIALKNCGGIPALVRLLRKTTDLEIRELVTGV--LWNLS- 661
            + A   + NL+   +     I    CG +  L RL  K  D  +R  + GV  L NLS 
Sbjct: 342 LKIASSTMCNLLLDFSPSKKDIL--ECGAVDILARLCEKQDDPPLR--LNGVWGLMNLSF 509

Query: 662 -SCDALKMPII 671
            + + +KM I+
Sbjct: 510 NADERVKMQIV 542
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|12963811|ref|NP_076232.1| eukaryotic translation
initiation factor 4E nuclear import factor 1 [Mus musculus]
         (983 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

30650                                                                  42   0.002
09292                                                                  34   0.28 
10711                                                                  32   1.4  
>30650
          Length = 825

 Score = 41.6 bits (96), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 32/93 (34%), Positives = 43/93 (46%), Gaps = 14/93 (15%)
 Frame = +2

Query: 262 GIVECNGGVAEEDEVEVILAQ--EPSADQEVPRDVILPEQSPGEFDFNEFFNLDKVPCLA 319
           G  ECNG V    EV     Q  +P+           P  S   FDFN+FFN++ +P L 
Sbjct: 56  GETECNGSVTNTVEVPTTEDQPSQPA-----------PYGSAALFDFNQFFNVEHIPGLG 202

Query: 320 SMIEDVL------GEGSVSA------SRFSRWF 340
             ++D+L       +G  SA      SRFS+WF
Sbjct: 203 P-VQDLLPDPHLDSQGVNSAVSNEGGSRFSKWF 298
>09292
          Length = 1486

 Score = 34.3 bits (77), Expect = 0.28,   Method: Compositional matrix adjust.
 Identities = 20/60 (33%), Positives = 30/60 (50%), Gaps = 1/60 (1%)
 Frame = -2

Query: 890 TPLHLAVMQQQLQRSVL-HPPGSSSQAAAISVQTPQNVPSRSGMPHMHSQLEHRTSQRSS 948
           TPLH+A+    L+  +L +  G++ Q     V    N PS   M H+H  L  RTS  ++
Sbjct: 477 TPLHIAISHHNLELVLLLYMCGANDQL----VDFDGNFPSCYSMCHIHGCLRRRTSHNAT 310
>10711
          Length = 2137

 Score = 32.0 bits (71), Expect = 1.4,   Method: Compositional matrix adjust.
 Identities = 20/60 (33%), Positives = 29/60 (48%)
 Frame = +1

Query: 879  ASHPLLNPRPGTPLHLAVMQQQLQRSVLHPPGSSSQAAAISVQTPQNVPSRSGMPHMHSQ 938
            + H L+    G PLH A   +QL+ S +           +  QTP  +PS S M H+HS+
Sbjct: 1546 SGHDLMLNIHGLPLHCAAFSRQLRASTI---------CTMPCQTPPPIPSFSIMSHVHSR 1698
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|13384700|ref|NP_079610.1| endoplasmic reticulum
protein ERp19 [Mus musculus]
         (170 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

15159                                                                  39   0.002
30644                                                                  32   0.12 
03582                                                                  31   0.25 
01584                                                                  31   0.32 
06936                                                                  30   0.39 
28335                                                                  29   0.95 
21509                                                                  28   2.2  
25088                                                                  28   2.2  
27967                                                                  27   2.8  
31166                                                                  26   8.6  
00396                                                                  26   9.8  
>15159
          Length = 1945

 Score = 38.5 bits (88), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 26/97 (26%), Positives = 46/97 (47%), Gaps = 3/97 (3%)
 Frame = +3

Query: 47  EAAASGLPLMVI-IHKSWCGACKALKPKFAESTEISELSHNFVMVNLEDEEEPRDEDFSP 105
           E A  G  L+V+  H +WCG CK + PK A+ +E         +++++ +E    ED + 
Sbjct: 111 EKAIQGGQLVVVDFHATWCGPCKVIAPKLAKWSEEDRFKETVKIISVDVDEL---EDLAG 281

Query: 106 DGGY--IPRILFLDPSGKVRPEIINESGNPSYKYFYV 140
           + G   +P   FL+   +     +  S  P  K +Y+
Sbjct: 282 EQGISAMPTFFFLEMEKR-----LMNSWEPITKNYYL 377
>30644
          Length = 845

 Score = 32.0 bits (71), Expect = 0.12,   Method: Compositional matrix adjust.
 Identities = 20/53 (37%), Positives = 31/53 (58%), Gaps = 6/53 (11%)
 Frame = -3

Query: 34  DHIHWRTLEDG-----KKEAAASGLPLMVIIHKSWCGACKALKPKF-AESTEI 80
           D +H  T +DG     KK+ +A+    +V+ +  WCG CK +KP F A +TE+
Sbjct: 480 DVVHIDT-DDGLTKLLKKDKSAA----LVMFYAPWCGYCKRMKPDFAAAATEV 337
>03582
          Length = 1967

 Score = 31.2 bits (69), Expect = 0.25,   Method: Compositional matrix adjust.
 Identities = 10/25 (40%), Positives = 18/25 (72%)
 Frame = +2

Query: 55  LMVIIHKSWCGACKALKPKFAESTE 79
           ++V  +  WCG CKAL P++A++ +
Sbjct: 173 VLVEFYAPWCGHCKALAPEYAKAAQ 247
>01584
          Length = 1540

 Score = 30.8 bits (68), Expect = 0.32,   Method: Compositional matrix adjust.
 Identities = 27/80 (33%), Positives = 35/80 (43%), Gaps = 3/80 (3%)
 Frame = +2

Query: 35   HIHWRTLEDGKKEAAASGLPLMVIIH---KSWCGACKALKPKFAESTEISELSHNFVMVN 91
            H+H RTL  GK   A   LPLM   H   K  CG  +  KP F  S   S  S    +  
Sbjct: 932  HLHCRTL*TGK*IHAGKALPLM*GSHR*KKEGCGK*RVKKPSF-PSPNWSPPSQGTRL*C 1108

Query: 92   LEDEEEPRDEDFSPDGGYIP 111
            L   ++P     +P+G  +P
Sbjct: 1109 LHPPQQP-----APEGKVLP 1153
>06936
          Length = 2198

 Score = 30.4 bits (67), Expect = 0.39,   Method: Compositional matrix adjust.
 Identities = 10/25 (40%), Positives = 15/25 (60%)
 Frame = +3

Query: 55   LMVIIHKSWCGACKALKPKFAESTE 79
            +++  +  WCG CK L PK+ E  E
Sbjct: 1248 VLIEFYAPWCGHCKTLAPKYDELAE 1322
>28335
          Length = 601

 Score = 29.3 bits (64), Expect = 0.95,   Method: Compositional matrix adjust.
 Identities = 14/69 (20%), Positives = 33/69 (47%)
 Frame = -2

Query: 25  RTGLGKGFGDHIHWRTLEDGKKEAAASGLPLMVIIHKSWCGACKALKPKFAESTEISELS 84
           +T +G+ F      + + + KK+       +++  +  WCG C+ L+PK+ E   + +  
Sbjct: 543 KTAVGRTFD-----KIVNNPKKD-------VLIEFYAPWCGHCQQLEPKYNELATLLKDE 400

Query: 85  HNFVMVNLE 93
            + V   ++
Sbjct: 399 PDIVXAKID 373
>21509
          Length = 754

 Score = 27.7 bits (60), Expect = 2.2,   Method: Compositional matrix adjust.
 Identities = 8/19 (42%), Positives = 13/19 (68%)
 Frame = -1

Query: 56  MVIIHKSWCGACKALKPKF 74
           +V+ +  WCG CK +KP +
Sbjct: 298 LVMFYAPWCGHCKKMKPAY 242
>25088
          Length = 1646

 Score = 27.7 bits (60), Expect = 2.2,   Method: Compositional matrix adjust.
 Identities = 12/24 (50%), Positives = 15/24 (62%)
 Frame = -3

Query: 147 QGMKEAQERLTGDAFREKHFQDEL 170
           Q M +A   L GDAFR+ H Q +L
Sbjct: 435 QAMFDAHHVLLGDAFRDAHHQADL 364
>27967
          Length = 370

 Score = 27.3 bits (59), Expect = 2.8,   Method: Compositional matrix adjust.
 Identities = 17/54 (31%), Positives = 24/54 (44%)
 Frame = +2

Query: 37  HWRTLEDGKKEAAASGLPLMVIIHKSWCGACKALKPKFAESTEISELSHNFVMV 90
           H  T   G        L + +++H     AC  LKP  A S  ++ L H+FV V
Sbjct: 53  HPATFIFGAIRVDKCSLTVFLVLHVLSDVACPILKPVNALSVSLAVLIHSFVSV 214
>31166
          Length = 444

 Score = 25.8 bits (55), Expect = 8.6,   Method: Compositional matrix adjust.
 Identities = 11/27 (40%), Positives = 14/27 (51%)
 Frame = +2

Query: 67  CKALKPKFAESTEISELSHNFVMVNLE 93
           C+   PKF E  E+S LSH     + E
Sbjct: 176 CRLCIPKFIEKREVSTLSHTISRTDTE 256
>00396
          Length = 823

 Score = 25.8 bits (55), Expect = 9.8,   Method: Compositional matrix adjust.
 Identities = 13/35 (37%), Positives = 19/35 (54%)
 Frame = +3

Query: 43  DGKKEAAASGLPLMVIIHKSWCGACKALKPKFAES 77
           DGK++A  + +  MV +H SW G    L P  A +
Sbjct: 456 DGKEQARPNEMNAMVRVHVSWSGRPHTLPPAQAST 560
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|27734140|ref|NP_775594.1| leucine-rich repeat,
immunoglobulin-like and transmembrane domains 2 [Mus musculus]
         (549 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

08294                                                                  40   0.002
36498                                                                  37   0.017
13135                                                                  35   0.11 
32888                                                                  27   0.63 
20110                                                                  31   1.4  
38127                                                                  30   2.3  
37675                                                                  29   4.1  
25766                                                                  29   4.3  
11910                                                                  29   5.7  
12764                                                                  29   5.7  
06162                                                                  28   9.1  
>08294
          Length = 1849

 Score = 40.4 bits (93), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 28/108 (25%), Positives = 44/108 (40%), Gaps = 4/108 (3%)
 Frame = +2

Query: 231 CQGPVSKAGQLLHETELGVCMKPTISTPSVNVTIQVGKNVTLQCFAQASPSPTIAWKYP- 289
           C     + G +     + +   P I+  S N+T+  G +  L C A+ SPSP IAW    
Sbjct: 11  CVATHPRQGVINATIHISIVEWPAITVKSNNITVFEGHSAILHCVAKGSPSPDIAWYRDS 190

Query: 290 ---LSTWREFDVLASPIAEGIILSQLVIPAAQLVDGGNYTCMAFNSIG 334
              L   R + +  +          + I    + D G Y C+A N+ G
Sbjct: 191 QPILPNARRYTLFKN--------GTMKIRQVFMEDNGMYACVANNTAG 310
>36498
          Length = 478

 Score = 37.4 bits (85), Expect = 0.017,   Method: Composition-based stats.
 Identities = 17/51 (33%), Positives = 28/51 (54%), Gaps = 1/51 (1%)
 Frame = +1

Query: 238 AGQLLHETELGVCMKPTIS-TPSVNVTIQVGKNVTLQCFAQASPSPTIAWK 287
           AG +     L +   PT++ TP   +T  VG  V ++C A+  P+PT+ W+
Sbjct: 7   AGTVTLTASLVIQGPPTVTVTPGTRITALVGDRVDIECVAEGDPTPTVFWR 159
>13135
          Length = 849

 Score = 34.7 bits (78), Expect = 0.11,   Method: Compositional matrix adjust.
 Identities = 28/91 (30%), Positives = 44/91 (48%), Gaps = 2/91 (2%)
 Frame = -1

Query: 246 ELGVCMKPTIST--PSVNVTIQVGKNVTLQCFAQASPSPTIAWKYPLSTWREFDVLASPI 303
           +L +   P IS    S +V+   G+++ L+C A   P+P++ W     T    ++L S  
Sbjct: 405 QLVIIQMPQISDLDTSSDVSKSEGQSLVLRCHASGRPTPSVKW-----TRMAGELLPSGG 241

Query: 304 AEGIILSQLVIPAAQLVDGGNYTCMAFNSIG 334
            E  + S LVIP  +    G Y C + NS G
Sbjct: 240 REH-LESDLVIPQLKPEHAGIYKCSSSNSAG 151
>32888
          Length = 418

 Score = 26.6 bits (57), Expect(2) = 0.63,   Method: Composition-based stats.
 Identities = 9/20 (45%), Positives = 12/20 (60%)
 Frame = -3

Query: 267 GKNVTLQCFAQASPSPTIAW 286
           G+ V L C A+  PSP + W
Sbjct: 233 GQTVRLDCRAKGKPSPKVTW 174

 Score = 23.9 bits (50), Expect(2) = 0.63,   Method: Composition-based stats.
 Identities = 10/25 (40%), Positives = 15/25 (60%)
 Frame = -2

Query: 311 QLVIPAAQLVDGGNYTCMAFNSIGR 335
           +L I +    D GNYTC+  N+ G+
Sbjct: 117 KLTIKSLGAEDKGNYTCIVSNTEGQ 43
>20110
          Length = 820

 Score = 30.8 bits (68), Expect = 1.4,   Method: Compositional matrix adjust.
 Identities = 43/173 (24%), Positives = 65/173 (37%), Gaps = 24/173 (13%)
 Frame = -1

Query: 185 CGAEFLSNMVLSLH----------NNPWLCDCRLRGLAQFVKSVGPPFILVNSYLV---- 230
           CG   +SN  +  H          NNP +   R   + + +      ++LV   LV    
Sbjct: 820 CGISDVSNTKIQEHISNDDKIEYQNNPMIGGLRKYEVQKRLSGDRETYMLVVRRLVETDA 641

Query: 231 ----CQGPVSKAGQLLHETELG---VCMKPTISTPSVNVTIQV--GKNVTLQCFAQASPS 281
               C   ++        T++G   V + P+I        +Q+  G+N TL C A   P+
Sbjct: 640 GIYTCTVRITAVSYEEWPTKIGNLTVQVPPSIKPGDTTAVLQIEQGQNSTLVCAASGIPA 461

Query: 282 PTIAWKYPLSTWREFDVLASPIAEGIILS-QLVIPAAQLVDGGNYTCMAFNSI 333
           P I       TW   D    PI      S  L +    + D G Y C+A N+I
Sbjct: 460 PNI-------TWTRSDGGFLPIGVAQFRSATLPMNNVTVRDMGVYRCVADNNI 323
>38127
          Length = 860

 Score = 30.0 bits (66), Expect = 2.3,   Method: Compositional matrix adjust.
 Identities = 18/75 (24%), Positives = 30/75 (40%), Gaps = 13/75 (17%)
 Frame = -1

Query: 268 KNVTLQCFAQASPSPTIAW-------------KYPLSTWREFDVLASPIAEGIILSQLVI 314
           +++ ++C     P P ++W             +Y L     +D         I  ++LVI
Sbjct: 638 ESLVIECKVLGYPKPVVSWYMDNVEIVDGADSRYSLKPANSYD------GASIEGAKLVI 477

Query: 315 PAAQLVDGGNYTCMA 329
              Q  D G YTCM+
Sbjct: 476 EEVQFDDAGEYTCMS 432
>37675
          Length = 741

 Score = 29.3 bits (64), Expect = 4.1,   Method: Compositional matrix adjust.
 Identities = 24/86 (27%), Positives = 36/86 (41%), Gaps = 3/86 (3%)
 Frame = +2

Query: 247 LGVCMKPTISTPSVNVTIQVGKNVTLQCFAQASPSPTIAWKY---PLSTWREFDVLASPI 303
           L V M P +     ++      N  ++C A+  P PTI+W +   P+S   +   L S  
Sbjct: 53  LKVQMPPVVKVSPHSLIYPARLNAKMKCHAEGVPKPTISWLFNNVPISEDPQHYDLES-- 226

Query: 304 AEGIILSQLVIPAAQLVDGGNYTCMA 329
                   LV+  A   D G Y C+A
Sbjct: 227 ----ANELLVVYNAGDQDTGAYKCVA 292
>25766
          Length = 469

 Score = 29.3 bits (64), Expect = 4.3,   Method: Composition-based stats.
 Identities = 12/41 (29%), Positives = 17/41 (41%)
 Frame = +1

Query: 247 LGVCMKPTISTPSVNVTIQVGKNVTLQCFAQASPSPTIAWK 287
           L +   P +S    N   QVG +V   C     P P + W+
Sbjct: 160 LRISSPPVVSVKQRNENRQVGSSVKFHCDVSGDPVPQVRWE 282
>11910
          Length = 437

 Score = 28.9 bits (63), Expect = 5.7,   Method: Composition-based stats.
 Identities = 13/42 (30%), Positives = 20/42 (47%)
 Frame = -3

Query: 489 PYNFSEWCWRRCPLHRKTLRCPQAVPQCKDNSFKDPSGVYED 530
           P+    WC  RCP+  +   CP  V + +DN  +D     +D
Sbjct: 255 PWY*RRWCADRCPV*LEKFCCP*VVNRMRDNMGRDKXAWQKD 130
>12764
          Length = 1055

 Score = 28.9 bits (63), Expect = 5.7,   Method: Compositional matrix adjust.
 Identities = 19/69 (27%), Positives = 32/69 (46%)
 Frame = +1

Query: 265 QVGKNVTLQCFAQASPSPTIAWKYPLSTWREFDVLASPIAEGIILSQLVIPAAQLVDGGN 324
           + G N+ L C  Q +P P +        WR+ +   + +A G   + L +    L D G 
Sbjct: 265 EEGLNLDLTCITQGNPLPFLVE------WRQ-EGENTTLATG---NTLTLTNLSLSDTGT 414

Query: 325 YTCMAFNSI 333
           YTC  +N++
Sbjct: 415 YTCTGYNTV 441
>06162
          Length = 3386

 Score = 28.1 bits (61), Expect = 9.1,   Method: Compositional matrix adjust.
 Identities = 23/83 (27%), Positives = 36/83 (43%), Gaps = 26/83 (31%)
 Frame = -1

Query: 220 PPFILVNSYLVCQGPVSKAGQL------------------------LHETELGVCMKPTI 255
           P FIL + YL+C  P + +G L                        L+ +  G+C +P+ 
Sbjct: 398 PSFILFDHYLICFFP*TISG*LYTKSVIYVSLNELCLRLQWTKH*KLNGSVAGLCPRPSS 219

Query: 256 S--TPSVNVTIQVGKNVTLQCFA 276
           +   P V V +Q+  NV LQC+ 
Sbjct: 218 APLVPRVCVAVQMDCNVLLQCWC 150
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|41281852|ref|NP_778172.1| amphiphysin [Mus musculus]
         (686 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

01494                                                                  41   0.002
29687                                                                  39   0.006
13664                                                                  37   0.022
12324                                                                  36   0.053
19469                                                                  31   1.9  
16716                                                                  29   5.1  
08543                                                                  25   7.5  
>01494
          Length = 2122

 Score = 40.8 bits (94), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 28/95 (29%), Positives = 41/95 (43%), Gaps = 3/95 (3%)
 Frame = +3

Query: 595 GAVDASLSAGDATQELPPGFLYKVETLHDFEAANSDELNLQRGDVVLVVPSDSEADQDAG 654
           GA D  ++  D T +L      +V+ LHD+ A   DEL+  +G ++  V     + QD G
Sbjct: 261 GAPDVYINPNDFTTKL------RVKALHDYNANRDDELSFCKGAIITNV-----SRQDGG 407

Query: 655 WL---VGVKESDWLQYRDLATYKGLFPENFTRRLE 686
           W     G K+  W            FP NF   +E
Sbjct: 408 WWRGDYGAKKQHW------------FPSNFVEEIE 476
>29687
          Length = 434

 Score = 39.3 bits (90), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 26/95 (27%), Positives = 42/95 (44%), Gaps = 3/95 (3%)
 Frame = -2

Query: 595 GAVDASLSAGDATQELPPGFLYKVETLHDFEAANSDELNLQRGDVVLVVPSDSEADQDAG 654
           G+VD  ++  D T +L      +V+ LHD+ A   DEL+  +G ++  V     + QD G
Sbjct: 343 GSVDLYINPNDFTTKL------RVKALHDYNAKREDELSFCKGAIITNV-----SRQDGG 197

Query: 655 WL---VGVKESDWLQYRDLATYKGLFPENFTRRLE 686
           W     G K+  W            FP N+   ++
Sbjct: 196 WWRGDYGTKKQHW------------FPSNYVEEID 128
>13664
          Length = 507

 Score = 37.4 bits (85), Expect = 0.022,   Method: Compositional matrix adjust.
 Identities = 17/42 (40%), Positives = 27/42 (64%)
 Frame = +2

Query: 617 KVETLHDFEAANSDELNLQRGDVVLVVPSDSEADQDAGWLVG 658
           KV  L+D++A  SDEL +  GDV++++  DSE+     W +G
Sbjct: 368 KVVALYDYKAQRSDELTILSGDVIMLLHKDSES-----WWMG 478
>12324
          Length = 946

 Score = 35.8 bits (81), Expect = 0.053,   Method: Compositional matrix adjust.
 Identities = 21/73 (28%), Positives = 31/73 (42%)
 Frame = +3

Query: 610 LPPGFLYKVETLHDFEAANSDELNLQRGDVVLVVPSDSEADQDAGWLVGVKESDWLQYRD 669
           +P  ++ KV  ++D+EA   DEL      V+ V+        D GW  GV +        
Sbjct: 672 MPATYIEKVVAIYDYEAEKDDELTFSENSVIYVI-----RKNDDGWWEGVMDG------- 815

Query: 670 LATYKGLFPENFT 682
                GLFP N+ 
Sbjct: 816 ---VTGLFPSNYV 845
>19469
          Length = 428

 Score = 30.8 bits (68), Expect = 1.9,   Method: Composition-based stats.
 Identities = 16/51 (31%), Positives = 28/51 (54%)
 Frame = -1

Query: 610 LPPGFLYKVETLHDFEAANSDELNLQRGDVVLVVPSDSEADQDAGWLVGVK 660
           +P   ++  + L+D  A   DEL  +RGDV+ ++  D+ A  D  WL  ++
Sbjct: 383 MPLWQVFLAKALYDNIAETPDELAFRRGDVITILEQDT-AGLDGWWLCSLR 234
>16716
          Length = 934

 Score = 29.3 bits (64), Expect = 5.1,   Method: Compositional matrix adjust.
 Identities = 29/107 (27%), Positives = 39/107 (36%)
 Frame = -1

Query: 576 EVATEPTPLDSQATLPASAGAVDASLSAGDATQELPPGFLYKVETLHDFEAANSDELNLQ 635
           EV+ EP P       P      D   +A   +Q   PG       L+D++AA+ DEL   
Sbjct: 574 EVSEEPAPQHEPEESPYEM--ADEEPAAPAQSQ---PGGGSTAIALYDYQAADDDELTFD 410

Query: 636 RGDVVLVVPSDSEADQDAGWLVGVKESDWLQYRDLATYKGLFPENFT 682
             DV+  +        D GW  G                GLFP N+ 
Sbjct: 409 PDDVITDIEM-----IDDGWWRGS----------CHGKNGLFPANYV 314
>08543
          Length = 599

 Score = 24.6 bits (52), Expect(2) = 7.5,   Method: Compositional matrix adjust.
 Identities = 10/21 (47%), Positives = 13/21 (61%)
 Frame = +2

Query: 642 VVPSDSEADQDAGWLVGVKES 662
           V+  D   DQ+ GWL+G KE 
Sbjct: 5   VIEYDDPEDQEEGWLMGQKEG 67

 Score = 22.7 bits (47), Expect(2) = 7.5,   Method: Composition-based stats.
 Identities = 8/10 (80%), Positives = 8/10 (80%)
 Frame = +1

Query: 674 KGLFPENFTR 683
           K LFP NFTR
Sbjct: 79  KALFPANFTR 108
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|47059486|ref|NP_064667.2| pyridoxal phosphatase [Mus
musculus]
         (292 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

05932                                                                  39   0.002
25975                                                                  28   5.3  
>05932
          Length = 522

 Score = 39.3 bits (90), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 16/41 (39%), Positives = 21/41 (51%)
 Frame = -1

Query: 208 GKPSPYMFQCITEDFSVDPARTLMVGDRLETDILFGHRCGM 248
           GKPS   F  + +     P  T+MVGD +E D+    RC M
Sbjct: 522 GKPSQAFFTSVLDSMGATPQHTVMVGDDIENDVXGAQRCAM 400
>25975
          Length = 417

 Score = 27.7 bits (60), Expect = 5.3,   Method: Compositional matrix adjust.
 Identities = 15/45 (33%), Positives = 21/45 (46%)
 Frame = -2

Query: 147 DEQFSFSRLTEACAHLRDPDCLLVATDRDPWHPLSDGSRTPGTGS 191
           DE    ++  E    + DP+  L+    D  HPLS  S  PG G+
Sbjct: 227 DEVHELAKAVETAVRMTDPEETLIVVTSDHAHPLSI-SGYPGRGT 96
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6753530|ref|NP_034094.1| crystallin, alpha B [Mus
musculus]
         (175 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

08623                                                                  38   0.002
28256                                                                  30   0.51 
>08623
          Length = 1531

 Score = 38.1 bits (87), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 22/75 (29%), Positives = 37/75 (49%), Gaps = 1/75 (1%)
 Frame = +1

Query: 75  FSVNLDVKHFSPEELKVKVLGDVIEVHGKHEERQDEHGFISREFHRKYRIPADVDPLTIT 134
           ++  L+V+ F  +++KV V    + V  +H    D HG I R F R+  +P  V   T+T
Sbjct: 181 YTAMLNVRSFRKDDIKVVVNERDVTVRCEHGPLYDHHGIIERRFERRITLPKTVKYETVT 360

Query: 135 SS-LSSDGVLTVNGP 148
              +   G+L +  P
Sbjct: 361 WKFMEKQGILLIEAP 405
>28256
          Length = 733

 Score = 30.0 bits (66), Expect = 0.51,   Method: Compositional matrix adjust.
 Identities = 14/51 (27%), Positives = 26/51 (50%), Gaps = 3/51 (5%)
 Frame = +2

Query: 17  FHSPSRLFDQFFGEHLLESDLFSTATSLSPFYLRPPSFL---RAPSWIDTG 64
           +  P+R+  +F GE  L  +    A + S  ++ PP++L   + P W + G
Sbjct: 101 YTRPTRIKLEFVGEGYLHPNCCGRANASSYGFVEPPTYLPNSKTPCWYEGG 253
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|161353447|ref|NP_064659.2| calcium channel,
voltage-dependent, alpha 2/delta subunit 2 [Mus musculus]
         (1154 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

19289                                                                  41   0.003
01169                                                                  32   1.4  
>19289
          Length = 734

 Score = 41.2 bits (95), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 23/94 (24%), Positives = 49/94 (52%), Gaps = 1/94 (1%)
 Frame = +3

Query: 517 GEKKNQLILGVMGIDVALNDIKRLTPNYTLGANGYVFAIDLNGYVLLHPNL-KPQTTNFR 575
            E++   ++G++G+D+ + DI +    Y    + Y F I  +GY + HP   +P  T+F 
Sbjct: 84  SERERVQLMGMVGVDLHMEDIAQDITYYNNNDHSYAFLITTHGYTIQHPVFQRPLRTSF- 260

Query: 576 EPVTLDFLDAELEDENKEEIRRSMIDGDKGHKQI 609
           +P+  D    E +    + +R +++  ++GH  +
Sbjct: 261 QPMHTDIRHFE-QHPGFDTVRHTILSREEGHTSL 359
>01169
          Length = 1267

 Score = 32.0 bits (71), Expect = 1.4,   Method: Compositional matrix adjust.
 Identities = 15/30 (50%), Positives = 20/30 (66%)
 Frame = +3

Query: 208 YTAVQIPTDIYKGSTVILNELNWTEALENV 237
           + A+QIPT I KG+  ILNE+N  +  E V
Sbjct: 636 FQALQIPTKITKGTIEILNEVNLIKEGERV 725
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6753738|ref|NP_036140.1| eukaryotic translation
initiation factor 2, subunit 3, structural gene X-linked [Mus
musculus]
         (472 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

22349                                                                  40   0.003
>22349
          Length = 662

 Score = 39.7 bits (91), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 39/167 (23%), Positives = 72/167 (43%), Gaps = 11/167 (6%)
 Frame = -2

Query: 38  RQATINIGTIGHVAHGKSTVVKAISGVHTVRFKNELERNITIKLGYANAKIYKLDDPSCP 97
           R+  IN+  IGHV  GKST+     G H +     +++    K        Y+ +     
Sbjct: 502 RKDHINVVFIGHVDAGKSTI-----GGHLLYLTGMVDKRTLEK--------YEREAKEKN 362

Query: 98  RPECYRSCGSSTPDEFPTD---IPGTKGNFKL-VRHVSFVDCPGHDILMATMLNGAAVMD 153
           R   Y S    T +E       +   +  F+  ++H + +D PGH   +  M+ GA+  D
Sbjct: 361 RETWYLSWALDTNNEEREKGKTVEVGRAFFETELKHFTVLDAPGHKSFVPNMICGASQAD 182

Query: 154 AALLLIAGNE----SCPQPQTSEHLAAI---EIMKLKHILILQNKID 193
            A+L+I+            + + H++         ++H+++L NK+D
Sbjct: 181 LAILVISARRGEF*DWFLSEEARHVSMPCW*RRQGVRHLIVLINKMD 41
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|75677397|ref|NP_031971.2| epidermal growth factor
receptor pathway substrate 8 [Mus musculus]
         (821 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

30740                                                                  40   0.003
37423                                                                  36   0.067
19469                                                                  35   0.17 
16716                                                                  33   0.47 
21148                                                                  31   1.6  
32580                                                                  29   7.1  
>30740
          Length = 488

 Score = 40.4 bits (93), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 17/52 (32%), Positives = 28/52 (53%), Gaps = 1/52 (1%)
 Frame = +2

Query: 527 VKTQPKKYAKSKYDFVARNSSELSVMKDDVLEILD-DRRQWWKVRNASGDSG 577
           ++  P++    KYDF  R+  +L   K D+LE++  D  +WW  R+  G  G
Sbjct: 167 IRPAPREKLMGKYDFSGRDPEDLPFSKGDILELISKDEEEWWTARDKHGRVG 322
>37423
          Length = 253

 Score = 35.8 bits (81), Expect = 0.067,   Method: Compositional matrix adjust.
 Identities = 17/37 (45%), Positives = 21/37 (56%)
 Frame = +2

Query: 690 QDELFQRLTIGRSAAQRKFHVPRQNVPVINITYDSSP 726
           QD  FQ   I   ++QR F  PR NVP +   Y+SSP
Sbjct: 110 QDGTFQPWNILHYSSQRIFMSPRWNVPTVEYHYNSSP 220
>19469
          Length = 428

 Score = 34.7 bits (78), Expect = 0.17,   Method: Compositional matrix adjust.
 Identities = 21/67 (31%), Positives = 33/67 (49%), Gaps = 4/67 (5%)
 Frame = -1

Query: 535 AKSKYDFVARNSSELSVMKDDVLEILDDRRQ----WWKVRNASGDSGFVPNNILDIMRTP 590
           AK+ YD +A    EL+  + DV+ IL+        WW + +  G  G  P N L I+   
Sbjct: 359 AKALYDNIAETPDELAFRRGDVITILEQDTAGLDGWW-LCSLRGRQGIAPGNRLKILSGM 183

Query: 591 ESGVGRA 597
             G+G++
Sbjct: 182 IEGMGKS 162
>16716
          Length = 934

 Score = 33.1 bits (74), Expect = 0.47,   Method: Compositional matrix adjust.
 Identities = 23/88 (26%), Positives = 43/88 (48%), Gaps = 14/88 (15%)
 Frame = -1

Query: 515 TPNHQVDRN-YDAVKTQPKKYAKSK----------YDFVARNSSELSVMKDDV---LEIL 560
            P H+ + + Y+    +P   A+S+          YD+ A +  EL+   DDV   +E++
Sbjct: 556 APQHEPEESPYEMADEEPAAPAQSQPGGGSTAIALYDYQAADDDELTFDPDDVITDIEMI 377

Query: 561 DDRRQWWKVRNASGDSGFVPNNILDIMR 588
           DD   WW+  +  G +G  P N +++ +
Sbjct: 376 DDG--WWRG-SCHGKNGLFPANYVELQQ 302
>21148
          Length = 664

 Score = 31.2 bits (69), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 31/108 (28%), Positives = 45/108 (41%), Gaps = 9/108 (8%)
 Frame = +3

Query: 466 QRKQDSKRLSTEHSNVSDYPPADGYAYSSSMY-----HRGPHADHGEAAM--PFKSTPNH 518
           ++KQD    +T HSN S YP    Y+ +   Y     HR  H+      M  PF      
Sbjct: 180 RKKQDFPSHNTSHSNTSPYPACPIYSXTIYXYLFRNKHRSKHSSQDN*TMDWPF------ 341

Query: 519 QVDRNYDAVKTQ--PKKYAKSKYDFVARNSSELSVMKDDVLEILDDRR 564
            ++RN   VKTQ  P+ +  S      RN ++      D   +L+  R
Sbjct: 342 -LNRNRHLVKTQIFPRGWTSS----CLRNETQSLKWPGDCAGLLEXGR 470
>32580
          Length = 411

 Score = 29.3 bits (64), Expect = 7.1,   Method: Compositional matrix adjust.
 Identities = 19/49 (38%), Positives = 22/49 (44%)
 Frame = +3

Query: 127 NFPLNTISHCQAVVHACSYDSILALVCKEPTQSKPDLHLFQCDEVKANL 175
           N P   + H QAVV   S D   +  C E TQ+ P   L Q D  K  L
Sbjct: 111 NIPWQCLPHTQAVVQEKSGDLTSSCPCAESTQTHPSATLGQSDPRKLPL 257
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|82931067|ref|XP_894899.1| PREDICTED:
phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 4, p150
isoform 2 [Mus musculus]
         (1358 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

10394                                                                  41   0.003
01707                                                                  40   0.005
01392                                                                  38   0.030
30256                                                                  32   0.035
03387                                                                  37   0.061
15910                                                                  37   0.068
19498                                                                  36   0.10 
13066                                                                  36   0.13 
01768                                                                  35   0.15 
19863                                                                  35   0.21 
26856                                                                  35   0.21 
03240                                                                  35   0.30 
04358                                                                  35   0.30 
16708                                                                  34   0.31 
36002                                                                  34   0.46 
01966                                                                  34   0.51 
19949                                                                  33   0.79 
29360                                                                  33   1.1  
26107                                                                  33   1.1  
01060                                                                  32   1.3  
23319                                                                  32   1.3  
03395                                                                  32   1.5  
03508                                                                  32   1.6  
07665                                                                  32   1.7  
11915                                                                  31   2.9  
00561                                                                  31   4.3  
33508                                                                  30   4.5  
01249                                                                  30   8.1  
06358                                                                  30   9.7  
>10394
          Length = 472

 Score = 41.2 bits (95), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 32/89 (35%), Positives = 44/89 (49%), Gaps = 1/89 (1%)
 Frame = +3

Query: 331 FAKETFLSADERILVIRKDLGNIIHNLCGHD-LPEKAEGESRASGLVVLVSVITSCLQTL 389
           FAK T L  +E IL       N +HN+ G D LPE A G++ A        V+ S +Q +
Sbjct: 51  FAKRTNLEKEETILKWILGDCNNVHNVYGRDNLPEHASGDAWA--------VVCSLIQQI 206

Query: 390 KSCDSKLAALELILHLAPRLSVEILLDRI 418
           KSC         I  L+P+  ++ L DRI
Sbjct: 207 KSCFKPSRPQRAISRLSPQALIQQLKDRI 293
>01707
          Length = 757

 Score = 40.4 bits (93), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 33/126 (26%), Positives = 48/126 (38%)
 Frame = +1

Query: 128 IAFQILTAVDQAHKSGVRHGDIKTENVMVTSWNWVLLTDFASFKPTYLPEDNPADFNYFF 187
           I +Q L AV+  H+    H D+K EN+++T    V L DF   +    P D   D+    
Sbjct: 376 IIYQTLLAVNFCHQYNTIHRDVKPENILITRQGQVKLCDFGFARILTGPGDEYTDY---- 543

Query: 188 DTSRRRTCYIAPERFVDGGMFATELEYMRDPSTPLVDLNSNQRARGELKRAMDIFSAGCV 247
             + R   Y APE  V    +                              +D+++ GCV
Sbjct: 544 -VATR--WYRAPELLVGDTQYGP---------------------------PVDVWAIGCV 633

Query: 248 IAELFT 253
            AEL T
Sbjct: 634 FAELLT 651
>01392
          Length = 1806

 Score = 37.7 bits (86), Expect = 0.030,   Method: Compositional matrix adjust.
 Identities = 47/191 (24%), Positives = 70/191 (36%), Gaps = 4/191 (2%)
 Frame = -1

Query: 124  EKRWIAFQILTAVDQAHKSGVRHGDIKTENVMVTSWNWVLLTDFASFK-PTYLPEDNPAD 182
            E   +   I  A+D  H  G+ H D+K EN++    + V+      F   + +  D    
Sbjct: 1788 EASLVVRHIARALDFLHSKGIAHRDLKPENILCEHLDDVVPVKICDFDLASGISCDGDGT 1609

Query: 183  FNYFFDTSRRRTCYIAPERFVDGGMFATELEYMRDPSTPLVDLNSNQRARGELKRAMDIF 242
                  T      Y+APE  V          Y +       DL S       +      F
Sbjct: 1608 KTPELLTPVGSAEYMAPE--VVDAWVGDSFSYDK-----RCDLWSLGIILYIMLCGYPPF 1450

Query: 243  SAGCVIAELFTEGVPLFDLSQLL--AYRNGHF-FPEQVLNKIEDRSIRDLVTQMINREPE 299
               C     +  G    D   +L  + ++GH+ FP Q    I   S +DL+  ++ REP 
Sbjct: 1449 YGQCGEDCGWNRGEACHDCQDMLFNSIQDGHYKFPSQEWTSIS-SSAKDLIRHLLVREPR 1273

Query: 300  KRLEAEDYLKQ 310
            KR  A D LK 
Sbjct: 1272 KRYSAADVLKH 1240
>30256
          Length = 961

 Score = 32.3 bits (72), Expect(2) = 0.035,   Method: Composition-based stats.
 Identities = 13/32 (40%), Positives = 25/32 (78%)
 Frame = +3

Query: 990  HEHKSAVNRIRVSDEHLLFATCSNDGTVKIWN 1021
            ++H+SAV  ++ + + ++  TCS+DGTVK+W+
Sbjct: 642  NKHRSAVTCLQFNKKFVV--TCSDDGTVKLWD 731

 Score = 24.3 bits (51), Expect(2) = 0.035,   Method: Composition-based stats.
 Identities = 6/13 (46%), Positives = 8/13 (61%)
 Frame = +1

Query: 970 WESKPPPPGWRPK 982
           W + P PPGW  +
Sbjct: 514 WATSPSPPGWNSR 552
>03387
          Length = 1891

 Score = 37.0 bits (84), Expect = 0.061,   Method: Compositional matrix adjust.
 Identities = 38/176 (21%), Positives = 70/176 (39%), Gaps = 2/176 (1%)
 Frame = +1

Query: 1185 ARIRRLSMHPLYQSWVIAAVQGNNEVSMWDMETGDRRLTLWASSAPPLSELQPSPHSVHG 1244
            A +  LS +P Y  +++A    +  V++WD+     +L  + S    + ++Q SPH+   
Sbjct: 652  AEVNCLSFNP-YSEFILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPHN--- 819

Query: 1245 IYCSPADGNPILLTAGSDMKIRFWDLVSPERSYVVAGSTGSPSVSYYKKIIEGTEVVQEI 1304
                      IL ++G+D ++  WDL                                +I
Sbjct: 820  --------ETILASSGTDRRLHVWDL-------------------------------SKI 882

Query: 1305 QNKQKVGPSDDTPRRGPESLPV--GHHDIITDIATFQTTQGFIVTASRDGIVKVWK 1358
              +Q    ++D P   PE L +  GH   I+D +        + + S D I++VW+
Sbjct: 883  GEEQLPEDAEDGP---PELLFIHGGHTAKISDFSWNPNEPWIVCSVSEDNIMQVWQ 1041
>15910
          Length = 1361

 Score = 36.6 bits (83), Expect = 0.068,   Method: Compositional matrix adjust.
 Identities = 50/204 (24%), Positives = 81/204 (39%), Gaps = 4/204 (1%)
 Frame = +2

Query: 110 LYDRISTRPFLNNIEKRWIAFQILTAVDQAHKSGVRHGDIKTENVMVTSWNWVLLTDFAS 169
           L+DRI TR      +       IL  V   H +GV H D+K EN++     +  +TD + 
Sbjct: 425 LFDRIVTRGQYTEKDAARAISDILHGVQYIHANGVVHRDLKPENLL-----YECMTDDSK 589

Query: 170 FKPTYLPEDNPADFNYFFDTSRRRTCYIAPERFVDGGMFATELEYMRDPSTPLVDLNSNQ 229
            K          +      T      Y APE  + G           D  TP VD+    
Sbjct: 590 LKLADFGLSRIIEPEVQMSTVCGTPGYCAPE-VLKG-----------DKYTPSVDM---- 721

Query: 230 RARGELKRAMDIFSAGCVIAELFTEGVPLFDLSQLLAYR---NGHF-FPEQVLNKIEDRS 285
                       +S G +   L     P F  ++   YR    G + F E+  ++I + +
Sbjct: 722 ------------WSVGVIAYILLCGYEPFFAENEFEMYRKIIKGEYKFDEEYWSEISENA 865

Query: 286 IRDLVTQMINREPEKRLEAEDYLK 309
            +D+V +++  +P+KRL A + L+
Sbjct: 866 -KDVVRKLLVIDPKKRLTATEALR 934
>19498
          Length = 903

 Score = 36.2 bits (82), Expect = 0.10,   Method: Compositional matrix adjust.
 Identities = 34/127 (26%), Positives = 48/127 (37%)
 Frame = -1

Query: 986  VAHLHEHKSAVNRIRVSDEHLLFATCSNDGTVKIWNSQKMEGKTTTTRSILTYSRIGGRV 1045
            VA L  H   V  +  S + L  A+CS D T+ +WN+ K   +    R         G V
Sbjct: 630  VATLRGHAGDVLDLAWSPQDLWLASCSVDNTIVVWNALKFSEQVAVIRG------HAGMV 469

Query: 1046 KTLTFCQGSHYLAIASDNGAVQLLGIEASKLPKSPKIHPLQSRILDQKEDGCVVDMHHFN 1105
            K +T+     YLA  SD+  +++                   R  D KE+ CV       
Sbjct: 468  KGVTWDPVGRYLASQSDDKTLRVW------------------RTSDWKEETCVKSCFKEC 343

Query: 1106 SGAQSVL 1112
             G   VL
Sbjct: 342  GGTTHVL 322
>13066
          Length = 551

 Score = 35.8 bits (81), Expect = 0.13,   Method: Compositional matrix adjust.
 Identities = 19/62 (30%), Positives = 32/62 (51%)
 Frame = +3

Query: 107 RDNLYDRISTRPFLNNIEKRWIAFQILTAVDQAHKSGVRHGDIKTENVMVTSWNWVLLTD 166
           R +L   I    F+   + +   +Q+ TA++  H   V H D+K EN++++S   V L D
Sbjct: 228 RGDLLTYIQEVGFVKEKQAKIWFYQMTTALNYLHSYDVAHRDLKCENILLSSHFNVKLAD 407

Query: 167 FA 168
           F 
Sbjct: 408 FG 413
>01768
          Length = 1424

 Score = 35.4 bits (80), Expect = 0.15,   Method: Compositional matrix adjust.
 Identities = 27/99 (27%), Positives = 47/99 (47%), Gaps = 2/99 (2%)
 Frame = +3

Query: 972  SKPPPPGWRPKGLLVAHLHEHKSAVNRIRVS-DEHLLFATCSNDGTVKIWNSQKMEGKTT 1030
            S+P   GW  +    A    H  +V  ++ S +E  +FA+CS D T++IWN+Q+   K  
Sbjct: 783  SQPSSSGWTTEKSSYA---AHTDSVEDVQWSPNEGNVFASCSVDRTLRIWNTQQKPSKAN 953

Query: 1031 TTRSILTYSRIGGRVKTLTFCQ-GSHYLAIASDNGAVQL 1068
                   +SR    +  + +     H LA   D+G +++
Sbjct: 954  VLTVPEAHSR---DINVINWNPIEKHLLASGGDDGIIKI 1061
>19863
          Length = 502

 Score = 35.0 bits (79), Expect = 0.21,   Method: Composition-based stats.
 Identities = 15/44 (34%), Positives = 23/44 (52%)
 Frame = +1

Query: 983  GLLVAHLHEHKSAVNRIRVSDEHLLFATCSNDGTVKIWNSQKME 1026
            G+    L  H   VN +  S +     +CSND TV+IWN ++ +
Sbjct: 67   GVQKLRLQGHAGWVNDVHFSQDQCWLLSCSNDNTVRIWNIEESD 198
>26856
          Length = 2013

 Score = 35.0 bits (79), Expect = 0.21,   Method: Compositional matrix adjust.
 Identities = 36/145 (24%), Positives = 60/145 (41%)
 Frame = +1

Query: 346 IRKDLGNIIHNLCGHDLPEKAEGESRASGLVVLVSVITSCLQTLKSCDSKLAALELILHL 405
           +R    N + + C    P+  E     + L  +  ++    Q +KS     A   +I+ L
Sbjct: 688 VRAASANKVKDFCQALSPDVRETIIMTNILPCVKDLVADANQHVKS-----ALASVIMGL 852

Query: 406 APRLSVEILLDRITPYLLHFSNDSVPRVRAEALRTLTKVLALVQEVPRNDVNIYPEYILP 465
           +P L  +  ++ + P  L    D  P VR   +  L  V  ++       +    + +LP
Sbjct: 853 SPILGKDNTIEHLLPLFLSQLKDECPDVRLNIISNLDCVNEVI------GIKQLSQSLLP 1014

Query: 466 GIAHLAQDDATIVRLAYAENIALLA 490
            I  LA+D    VRLA  E + LLA
Sbjct: 1015AIVELAEDTKWRVRLAIIEYMPLLA 1089
>03240
          Length = 1683

 Score = 34.7 bits (78), Expect = 0.30,   Method: Compositional matrix adjust.
 Identities = 13/43 (30%), Positives = 25/43 (58%)
 Frame = -3

Query: 126 RWIAFQILTAVDQAHKSGVRHGDIKTENVMVTSWNWVLLTDFA 168
           R+   +++ A++  H+ G  H DIK +N+++     + LTDF 
Sbjct: 982 RFYVAELVQAIESVHRMGFIHRDIKPDNILIDRNGHIKLTDFG 854
>04358
          Length = 2430

 Score = 34.7 bits (78), Expect = 0.30,   Method: Compositional matrix adjust.
 Identities = 14/32 (43%), Positives = 19/32 (59%)
 Frame = +1

Query: 1326 VGHHDIITDIATFQTTQGFIVTASRDGIVKVW 1357
             GH D+I+ I    T  G I+TAS D  V++W
Sbjct: 1411 TGHDDVISSIRFLHTDPGLIMTASHDHTVRIW 1506
>16708
          Length = 1397

 Score = 34.3 bits (77), Expect = 0.31,   Method: Compositional matrix adjust.
 Identities = 26/86 (30%), Positives = 40/86 (46%), Gaps = 7/86 (8%)
 Frame = -1

Query: 128  IAFQILTAVDQAHKSGVRHGDIKTENVMVTSWNWVLLTDFASFKPTYLPEDNPADFNYFF 187
            IA Q + A++  H+ GV H D+K +NV+V +     LTD+      Y     P +  +  
Sbjct: 1079 IAGQXVCALEHIHELGVVHMDVKADNVLVDAHGNCKLTDYG-IAQLYKVYPAPTE-THSS 906

Query: 188  DTSRRRTCYIAP-------ERFVDGG 206
              + +RT Y  P       ERF + G
Sbjct: 905  GCTNKRTFYTRPPATMTPSERFSEEG 828
>36002
          Length = 253

 Score = 33.9 bits (76), Expect = 0.46,   Method: Compositional matrix adjust.
 Identities = 25/71 (35%), Positives = 33/71 (46%), Gaps = 3/71 (4%)
 Frame = +1

Query: 243 SAGCVIAELFTEGVPLFDLSQLLAYR---NGHFFPEQVLNKIEDRSIRDLVTQMINREPE 299
           S G  +AE    G    D  +LL  R     +FFP    + I   S +DL+  ++ REP 
Sbjct: 1   SXGRTVAE---PGEACQDCQELLFNRIQDGNYFFPSMEWSAISS-SAKDLIRHLLVREPR 168

Query: 300 KRLEAEDYLKQ 310
           KR  A D LK 
Sbjct: 169 KRYSAADVLKH 201
>01966
          Length = 1735

 Score = 33.9 bits (76), Expect = 0.51,   Method: Compositional matrix adjust.
 Identities = 13/48 (27%), Positives = 26/48 (54%)
 Frame = -1

Query: 129  AFQILTAVDQAHKSGVRHGDIKTENVMVTSWNWVLLTDFASFKPTYLP 176
             FQI+T ++  H+  + H D+K +N+++     + + DF   +   LP
Sbjct: 1390 VFQIVTGINFCHQRRIVHRDLKPQNLLINHTGAIKIADFGMARTFALP 1247
>19949
          Length = 903

 Score = 33.1 bits (74), Expect = 0.79,   Method: Compositional matrix adjust.
 Identities = 18/49 (36%), Positives = 25/49 (51%)
 Frame = +2

Query: 983  GLLVAHLHEHKSAVNRIRVSDEHLLFATCSNDGTVKIWNSQKMEGKTTT 1031
            G L+  L  H+ AVN I       L A+ S D TVK W+ +  +  +TT
Sbjct: 215  GKLLTDLKLHRDAVNTIEFHPHEFLLASGSADRTVKFWDLETFQLISTT 361
>29360
          Length = 363

 Score = 32.7 bits (73), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 21/61 (34%), Positives = 32/61 (52%), Gaps = 4/61 (6%)
 Frame = +3

Query: 101 LFRQYVRDNLYDRISTRPF----LNNIEKRWIAFQILTAVDQAHKSGVRHGDIKTENVMV 156
           L  + +  NLYD +    F    L  I  R I  Q+LTA+ +  + G+ H D+K EN+M+
Sbjct: 186 LVFEMLEQNLYDFLKQNKFQPLPLKYI--RPITQQVLTALRKLKQLGLIHADLKPENIML 359

Query: 157 T 157
            
Sbjct: 360 V 362
>26107
          Length = 1338

 Score = 32.7 bits (73), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 15/52 (28%), Positives = 32/52 (61%)
 Frame = -3

Query: 981  PKGLLVAHLHEHKSAVNRIRVSDEHLLFATCSNDGTVKIWNSQKMEGKTTTT 1032
            PKG++     + + +V  +    ++L+ ++ +NDG VK+W+++K    TTT+
Sbjct: 754  PKGVM-----DTQQSVTCVLYQTDNLIISSGANDGCVKMWDTRKWYTNTTTS 614
>01060
          Length = 1800

 Score = 32.3 bits (72), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 35/170 (20%), Positives = 71/170 (41%), Gaps = 6/170 (3%)
 Frame = +1

Query: 13  ILSVESYFSDIHDFEYDKSLGSTRFFKVARAKHR---EGLVVVKVFAIQDPTLPLTSYKQ 69
           ++  E+  SD+ DF+    +G   +  V + +HR     L + K+          +S  +
Sbjct: 49  MMDFETALSDLTDFQ---KIGEGTYGVVYKCRHRATGRKLAMKKIRLRGSEDGVPSSAIR 219

Query: 70  ELEELKIRLHSAQNCLPFQXXXXXXXXXXXMLFRQYVRDNLYDRISTRPFLNNIEKRWI- 128
           E+  L+   H+   CL               L  +++  +L   I   P    +++R + 
Sbjct: 220 EIAMLRELRHTNIVCLE----DVIMEDERLFLVFEFLSMDLKMYIDKFPEGVVLDRRLVK 387

Query: 129 --AFQILTAVDQAHKSGVRHGDIKTENVMVTSWNWVLLTDFASFKPTYLP 176
              FQI+T +   H+  + H D+K +N+++     + + DF   +   LP
Sbjct: 388 SYVFQIVTGIXFCHQRRIVHRDLKPQNLLINHTGAIKIADFGMARTFALP 537
>23319
          Length = 2235

 Score = 32.3 bits (72), Expect = 1.3,   Method: Composition-based stats.
 Identities = 28/106 (26%), Positives = 46/106 (43%), Gaps = 33/106 (31%)
 Frame = +3

Query: 238 AMDIFSAGCVIAELFTEGVPLF-------------------------DLSQLLAYRNGHF 272
           ++D++SAGC+ AEL   G PLF                          ++QL  YR    
Sbjct: 36  SIDMWSAGCIFAELANAGRPLFPGNDDDDQLKRIFKLLGTPTEDQWPGMTQLPNYR---M 206

Query: 273 FP--------EQVLNKIEDRSIRDLVTQMINREPEKRLEAEDYLKQ 310
           FP        +QV+ K+  +  RDL+  ++   P  R+ A++ L+ 
Sbjct: 207 FPMYHVTTTWQQVVPKLNSKG-RDLLQCLLVCCPSDRMSADEALQH 341
>03395
          Length = 2795

 Score = 32.0 bits (71), Expect = 1.5,   Method: Composition-based stats.
 Identities = 14/42 (33%), Positives = 23/42 (54%)
 Frame = +2

Query: 980  RPKGLLVAHLHEHKSAVNRIRVSDEHLLFATCSNDGTVKIWN 1021
            + +G LVA++ EHK  V  I++        + S DG+  IW+
Sbjct: 107  KTRGDLVANMKEHKGKVTAIQIHTNDRCCVSASTDGSTIIWD 232
>03508
          Length = 1463

 Score = 32.0 bits (71), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 12/35 (34%), Positives = 21/35 (60%)
 Frame = +1

Query: 126 RWIAFQILTAVDQAHKSGVRHGDIKTENVMVTSWN 160
           R+  ++++ A+D  H  G+ H D+K  NVM+   N
Sbjct: 880 RFYLYELMKALDFCHSMGIMHRDVKPHNVMIDHEN 984
>07665
          Length = 435

 Score = 32.0 bits (71), Expect = 1.7,   Method: Composition-based stats.
 Identities = 14/48 (29%), Positives = 25/48 (52%)
 Frame = -2

Query: 1123 GWDLRSSSNAWTLKHDLKSGLITSFAVDIHQCWLCIGTSSGAMACWDM 1170
            GWDL    N +TL+H+    +I +     ++ WLC+     ++  WD+
Sbjct: 395  GWDLNDGKNLYTLEHN---DIINALCFSPNRYWLCVAYGP-SIKIWDL 264
>11915
          Length = 737

 Score = 31.2 bits (69), Expect = 2.9,   Method: Composition-based stats.
 Identities = 14/39 (35%), Positives = 24/39 (61%), Gaps = 1/39 (2%)
 Frame = +1

Query: 983  GLLVAHLHEHKSAVNRIR-VSDEHLLFATCSNDGTVKIW 1020
            G L+  + +HK+ V+ +   +D  L   + S+DGTVK+W
Sbjct: 502  GKLLIEMMDHKATVHDLHFAADNSLCLMSASHDGTVKLW 618
>00561
          Length = 1003

 Score = 30.8 bits (68), Expect = 4.3,   Method: Compositional matrix adjust.
 Identities = 16/56 (28%), Positives = 29/56 (51%), Gaps = 2/56 (3%)
 Frame = -3

Query: 1219 DRRLTLWASSAPPLSELQPSPHS--VHGIYCSPADGNPILLTAGSDMKIRFWDLVS 1272
            D+ + LW + A     +Q   H+  V  +  SP   NPI+++ G D  ++ W+L +
Sbjct: 677  DKTIKLWNTLAECKFTIQEDGHTDWVSCVRFSPNHSNPIIVSCGWDRTVKVWNLAN 510
>33508
          Length = 606

 Score = 30.4 bits (67), Expect = 4.5,   Method: Composition-based stats.
 Identities = 14/27 (51%), Positives = 20/27 (74%)
 Frame = -2

Query: 619 LLQQGLSDAEEFVIVKALNALTCMCQL 645
           L+Q+ L D ++FVIV+AL  L  +CQL
Sbjct: 86  LVQRSLLDDDKFVIVRALEMLGKLCQL 6
>01249
          Length = 1743

 Score = 29.6 bits (65), Expect = 8.1,   Method: Compositional matrix adjust.
 Identities = 34/124 (27%), Positives = 56/124 (45%), Gaps = 4/124 (3%)
 Frame = -1

Query: 1009 ATCSNDGTVKIWNSQKMEGKTTTTRSILTYSRIGGRVKTLTFCQGSHYLAIASDNGAV-- 1066
            A+ S+DGT K+W+   + G     R+++  + +G     L   +  H+L    DNG +  
Sbjct: 1158 ASSSSDGTCKLWD--MLSG--ALLRTMVYETGVG----CLIMDKQEHFLLAGLDNGDILC 1003

Query: 1067 -QLLG-IEASKLPKSPKIHPLQSRILDQKEDGCVVDMHHFNSGAQSVLAYATVNGSLVGW 1124
              L G I  S++  S        R+L    D   V    F+S  Q  LA  + NG ++ W
Sbjct: 1002 SPLFGQISQSEVFVSKHTTKAGERVLQGHSD--AVTCLAFSSDGQR-LASGSQNGKVIIW 832

Query: 1125 DLRS 1128
            ++ S
Sbjct: 831  NMES 820
>06358
          Length = 1517

 Score = 29.6 bits (65), Expect = 9.7,   Method: Compositional matrix adjust.
 Identities = 21/72 (29%), Positives = 39/72 (54%), Gaps = 7/72 (9%)
 Frame = +3

Query: 240 DIFSAGCVIAELFTEGVPLFDLS-QLLAYRNGHFFPEQV------LNKIEDRSIRDLVTQ 292
           D+FS G ++  +F +G PLF+ + +L A+++     E++      L  +    +RD V  
Sbjct: 648 DMFSLGLLVYSVFAKGKPLFECNGELSAFKSNA---EELRHMRVSLLGVVPEDLRDHVKL 818

Query: 293 MINREPEKRLEA 304
           ++N EP  R +A
Sbjct: 819 LLNIEPAVRPDA 854
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|30424699|ref|NP_780307.1| coiled-coil domain
containing 126 [Mus musculus]
         (140 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

03997                                                                  36   0.004
29446                                                                  26   4.9  
>03997
          Length = 1082

 Score = 36.2 bits (82), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 23/60 (38%), Positives = 36/60 (60%), Gaps = 5/60 (8%)
 Frame = +3

Query: 17  LLLVFGLI-WGLMLLHYTLQQP----RRQSSVKLREQILDLSKRYVKALAEESRSTADVD 71
           LL+ FG + W LML H TLQQ     RRQ++  +R  I  + +R+++ + + SR+ A V 
Sbjct: 438 LLIAFGQVTWTLMLAHATLQQEALAWRRQTNSNIRRLIQQM-RRHLRRVEKASRAKASVT 614
>29446
          Length = 1445

 Score = 26.2 bits (56), Expect = 4.9,   Method: Compositional matrix adjust.
 Identities = 11/21 (52%), Positives = 15/21 (71%)
 Frame = +3

Query: 17   LLLVFGLIWGLMLLHYTLQQP 37
            L L+ GLIW L +LHY++  P
Sbjct: 1269 LKLILGLIWTL-ILHYSISMP 1328
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|88853584|ref|NP_001028592.1| dedicator of cytokinesis
1 [Mus musculus]
         (1865 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

16716                                                                  41   0.004
20131                                                                  37   0.061
33143                                                                  37   0.064
19469                                                                  35   0.26 
12324                                                                  34   0.44 
13664                                                                  34   0.65 
28095                                                                  33   1.1  
26400                                                                  30   6.3  
>16716
          Length = 934

 Score = 41.2 bits (95), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 25/85 (29%), Positives = 39/85 (45%), Gaps = 1/85 (1%)
 Frame = -1

Query: 14  GVAFYNYDARGADELSLQIGDTVHILETY-EGWYRGYTLRKKSKKGIFPASYIHLKEAIV 72
            +A Y+Y A   DEL+    D +  +E   +GW+RG       K G+FPA+Y+ L++   
Sbjct: 463 AIALYDYQAADDDELTFDPDDVITDIEMIDDGWWRGSC---HGKNGLFPANYVELQQ--- 302

Query: 73  EGKGQHETVIPGDLPLIQEVTTTLR 97
                         PL+Q  +T  R
Sbjct: 301 ------------*FPLLQAASTQQR 263
>20131
          Length = 574

 Score = 37.4 bits (85), Expect = 0.061,   Method: Composition-based stats.
 Identities = 19/58 (32%), Positives = 36/58 (62%)
 Frame = -2

Query: 8   KREEKYGVAFYNYDARGADELSLQIGDTVHILETYEGWYRGYTLRKKSKKGIFPASYI 65
           ++E +Y VA Y+Y +    +L+   GD + + +  E W+ G TL +K+  G+FP++Y+
Sbjct: 492 RKEGEYYVAMYSYVSGETADLTFNEGDMILVTKKDEDWWTG-TLGEKT--GMFPSTYV 328

 Score = 33.5 bits (75), Expect = 0.94,   Method: Composition-based stats.
 Identities = 17/49 (34%), Positives = 28/49 (57%), Gaps = 3/49 (6%)
 Frame = -2

Query: 20  YDARGADELSLQIGDTVHILE-TYEGWYRGYTLRKKSKK--GIFPASYI 65
           Y A G  +LSL+ G+ +H+ + +  GW+ G    +  +K  G FPA Y+
Sbjct: 258 YTATGNGQLSLEPGNLIHVRQKSPRGWWEGELQARGQRKKIGWFPADYV 112
>33143
          Length = 1469

 Score = 37.4 bits (85), Expect = 0.064,   Method: Compositional matrix adjust.
 Identities = 20/52 (38%), Positives = 32/52 (61%), Gaps = 4/52 (7%)
 Frame = -2

Query: 20  YDARGADELSLQIGDTVHILE--TYEG--WYRGYTLRKKSKKGIFPASYIHL 67
           Y A  +DE+SLQ+GD V +++  + EG  W+RG   +K  + G FPA  + +
Sbjct: 412 YAAHASDEISLQVGDFVSVIDMPSSEGTKWWRG---KKGFEVGFFPADCVEV 266
>19469
          Length = 428

 Score = 35.0 bits (79), Expect = 0.26,   Method: Compositional matrix adjust.
 Identities = 19/63 (30%), Positives = 33/63 (52%), Gaps = 1/63 (1%)
 Frame = -1

Query: 16  AFYNYDARGADELSLQIGDTVHILETYEGWYRGYTLRK-KSKKGIFPASYIHLKEAIVEG 74
           A Y+  A   DEL+ + GD + ILE       G+ L   + ++GI P + + +   ++EG
Sbjct: 353 ALYDNIAETPDELAFRRGDVITILEQDTAGLDGWWLCSLRGRQGIAPGNRLKILSGMIEG 174

Query: 75  KGQ 77
            G+
Sbjct: 173 MGK 165
>12324
          Length = 946

 Score = 34.3 bits (77), Expect = 0.44,   Method: Composition-based stats.
 Identities = 18/63 (28%), Positives = 34/63 (53%), Gaps = 1/63 (1%)
 Frame = +3

Query: 4   WVPTKREEKYGVAFYNYDARGADELSLQIGDTVHIL-ETYEGWYRGYTLRKKSKKGIFPA 62
           ++P    EK  VA Y+Y+A   DEL+      ++++ +  +GW+ G         G+FP+
Sbjct: 669 YMPATYIEKV-VAIYDYEAEKDDELTFSENSVIYVIRKNDDGWWEGVM---DGVTGLFPS 836

Query: 63  SYI 65
           +Y+
Sbjct: 837 NYV 845
>13664
          Length = 507

 Score = 33.9 bits (76), Expect = 0.65,   Method: Composition-based stats.
 Identities = 17/46 (36%), Positives = 28/46 (60%), Gaps = 1/46 (2%)
 Frame = +2

Query: 7   TKREEKYGVAFYNYDARGADELSLQIGDTVHIL-ETYEGWYRGYTL 51
           + R+ K  VA Y+Y A+ +DEL++  GD + +L +  E W+ G  L
Sbjct: 350 STRKPKKVVALYDYKAQRSDELTILSGDVIMLLHKDSESWWMGELL 487
>28095
          Length = 597

 Score = 33.1 bits (74), Expect = 1.1,   Method: Composition-based stats.
 Identities = 16/51 (31%), Positives = 29/51 (56%), Gaps = 1/51 (1%)
 Frame = +3

Query: 16  AFYNYDARGADELSLQIGDTVHILETYE-GWYRGYTLRKKSKKGIFPASYI 65
           A Y+Y A  +DE+S   GDT+   +  + GW  G  + +  + G+ P++Y+
Sbjct: 270 AMYDYQAADSDEVSFNDGDTIIECQPVDAGWMTG-RVERTGQYGMLPSNYV 419
>26400
          Length = 431

 Score = 30.4 bits (67), Expect = 6.3,   Method: Composition-based stats.
 Identities = 15/35 (42%), Positives = 18/35 (51%)
 Frame = -1

Query: 1199 CTVNVLNFYKEIEREEMYIRYLYKLCDLHKECDNY 1233
            CT NVLN     E   +YIR+LYK C    +   Y
Sbjct: 341  CTANVLN-----ENMRLYIRHLYKSCSSFGQSQRY 252
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|94403806|ref|XP_001003603.1| PREDICTED: hypothetical
protein isoform 2 [Mus musculus]
         (316 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

01109                                                                  39   0.004
34514                                                                  36   0.018
15500                                                                  30   1.6  
20939                                                                  30   1.6  
36838                                                                  28   3.7  
19107                                                                  27   7.5  
>01109
          Length = 2130

 Score = 38.5 bits (88), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 29/98 (29%), Positives = 51/98 (52%)
 Frame = +3

Query: 146 LKELTLSANPGITPKGWSRLAIAVAHSSQVRVLNLDYNPLGDHVAGMLAVAVASSRTLEV 205
           L+EL +  N GI   G + L  A+A ++++RVLNL+ N   +  +  +A  +   + LEV
Sbjct: 459 LEELAMPQN-GINLPGITALVEAIAVNTKLRVLNLNDNTFTETGSHEMAKVLPKLQELEV 635

Query: 206 LDLEGTGLTNQSAQTLLDMVENYPTALRSLVLAENSIS 243
           ++     L    A  + D V++    L+ L+L+ N I 
Sbjct: 636 INFGDCLLRTGGALAIADAVKDGQHKLKELILSGNEIK 749
>34514
          Length = 1178

 Score = 36.2 bits (82), Expect = 0.018,   Method: Compositional matrix adjust.
 Identities = 27/82 (32%), Positives = 37/82 (45%)
 Frame = -3

Query: 164 RLAIAVAHSSQVRVLNLDYNPLGDHVAGMLAVAVASSRTLEVLDLEGTGLTNQSAQTLLD 223
           RLA +     Q+  LNLDYN  GD     L   + ++ TL  + L    L   S   L  
Sbjct: 435 RLARSFVFCDQMTTLNLDYNEFGDEGVKYLCDGLRNNTTLLSISLCYCDLGVASGTYLGS 256

Query: 224 MVENYPTALRSLVLAENSISPE 245
           +V    TA+R L L  N++  E
Sbjct: 255 IVS--TTAVRELYLDGNNLQCE 196
>15500
          Length = 550

 Score = 29.6 bits (65), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 25/97 (25%), Positives = 43/97 (44%)
 Frame = +2

Query: 133 ICGLLPPDGAKSGLKELTLSANPGITPKGWSRLAIAVAHSSQVRVLNLDYNPLGDHVAGM 192
            CGL   + A  G    TLS         W++         ++  LNL +N + D     
Sbjct: 191 FCGLTNSNAAGFGRALGTLST--------WNK---------KLLTLNLSHNSITDLGVSH 319

Query: 193 LAVAVASSRTLEVLDLEGTGLTNQSAQTLLDMVENYP 229
           LA  + ++RTL VL+L    + ++ A  L  ++ ++P
Sbjct: 320 LAHGLMTNRTLLVLNLASNQIGDEGAAALAQVLSHFP 430

 Score = 27.7 bits (60), Expect = 6.5,   Method: Compositional matrix adjust.
 Identities = 30/94 (31%), Positives = 42/94 (44%), Gaps = 4/94 (4%)
 Frame = +2

Query: 154 NPGITPKGWSRLAIAVAHSSQVRVLNLDYNPL-GDHVAGMLAVAVASSRTLEVLDLEGTG 212
           N G+T +    LA  +     +  L LD NPL GD     L+  +     LE L L   G
Sbjct: 29  NTGLTAQTIDMLAYFLPRCHSLTTLLLDANPLIGD---ANLSDLINLHSPLENLSLRFCG 199

Query: 213 LTNQSAQTL---LDMVENYPTALRSLVLAENSIS 243
           LTN +A      L  +  +   L +L L+ NSI+
Sbjct: 200 LTNSNAAGFGRALGTLSTWNKKLLTLNLSHNSIT 301
>20939
          Length = 706

 Score = 29.6 bits (65), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 14/35 (40%), Positives = 19/35 (54%)
 Frame = -1

Query: 11  EPLSGAEVRDICRGLRDNAVRLLSLRGCRLCDRDF 45
            P S AE+  +C   +D + R L  R CR+  RDF
Sbjct: 451 RPFSAAEIIGVC*HFQDKS*RHLP*RTCRVLARDF 347
>36838
          Length = 292

 Score = 28.5 bits (62), Expect = 3.7,   Method: Compositional matrix adjust.
 Identities = 9/25 (36%), Positives = 19/25 (76%)
 Frame = +3

Query: 147 KELTLSANPGITPKGWSRLAIAVAH 171
           K +++  +PG++PK WS L++ ++H
Sbjct: 195 KTISILLSPGVSPKAWSCLSVYLSH 269
>19107
          Length = 936

 Score = 27.3 bits (59), Expect = 7.5,   Method: Compositional matrix adjust.
 Identities = 22/82 (26%), Positives = 37/82 (45%)
 Frame = -1

Query: 161 GWSRLAIAVAHSSQVRVLNLDYNPLGDHVAGMLAVAVASSRTLEVLDLEGTGLTNQSAQT 220
           G  R+A  + H+  +  LNL  N +       LA  +  +  L+ LDL    L +  A  
Sbjct: 672 GAFRMAENLMHNYTLTYLNLSCNRITRDGVKELAKVLKQNTALQTLDLGYNRLEDDGAIH 493

Query: 221 LLDMVENYPTALRSLVLAENSI 242
           + + +    T L+ LV+  N+I
Sbjct: 492 IAEALTTLNTKLQCLVVVHNNI 427
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|30425288|ref|NP_780731.1| leucine rich repeat and
fibronectin type III, extracellular 1 [Mus musculus]
         (828 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

19380                                                                  40   0.005
30747                                                                  39   0.007
20775                                                                  34   0.21 
18260                                                                  32   1.1  
19107                                                                  31   2.1  
02787                                                                  31   2.3  
>19380
          Length = 467

 Score = 39.7 bits (91), Expect = 0.005,   Method: Composition-based stats.
 Identities = 24/80 (30%), Positives = 36/80 (45%)
 Frame = +2

Query: 86  LTYLNLTKNEIGYIEDGAFSGQFNLQVLQLGYNRLRNLTEGMLRGLSKLEYLYLQANLIE 145
           L YL +  + I  I +  F+G   L+ L    NRLR +  G    +  L  L L  N +E
Sbjct: 8   LEYLTVENSRINRINNKTFNGLKFLKTLNFRGNRLRVIESGTFHSIGNLSSLSLSDNPLE 187

Query: 146 VVMASAFWECPNIVNIDLSM 165
            V   AF    N+ ++ + M
Sbjct: 188 KVEEEAFVNLENLTSLHMDM 247

 Score = 33.5 bits (75), Expect = 0.37,   Method: Composition-based stats.
 Identities = 16/51 (31%), Positives = 27/51 (52%)
 Frame = +2

Query: 65  LRLNENRIRSVQYASLSRFGNLTYLNLTKNEIGYIEDGAFSGQFNLQVLQL 115
           L    NR+R ++  +    GNL+ L+L+ N +  +E+ AF    NL  L +
Sbjct: 89  LNFRGNRLRVIESGTFHSIGNLSSLSLSDNPLEKVEEEAFVNLENLTSLHM 241

 Score = 32.0 bits (71), Expect = 1.1,   Method: Composition-based stats.
 Identities = 18/61 (29%), Positives = 30/61 (49%)
 Frame = +2

Query: 132 SKLEYLYLQANLIEVVMASAFWECPNIVNIDLSMNRIQQLGSGTFAGLTKLSVCEIYSNP 191
           SKLEYL ++ + I  +    F     +  ++   NR++ + SGTF  +  LS   +  NP
Sbjct: 2   SKLEYLTVENSRINRINNKTFNGLKFLKTLNFRGNRLRVIESGTFHSIGNLSSLSLSDNP 181

Query: 192 F 192
            
Sbjct: 182 L 184
>30747
          Length = 1168

 Score = 39.3 bits (90), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 31/107 (28%), Positives = 53/107 (49%)
 Frame = +3

Query: 70  NRIRSVQYASLSRFGNLTYLNLTKNEIGYIEDGAFSGQFNLQVLQLGYNRLRNLTEGMLR 129
           N I  +Q+   ++  +L  L L  N++  ++         L  LQL YN++ +L +G L 
Sbjct: 291 NYITKIQHLEFTQ--DLRDLKLYDNKVSQVQ--GLESLKELCSLQLQYNQIESLGKG-LN 455

Query: 130 GLSKLEYLYLQANLIEVVMASAFWECPNIVNIDLSMNRIQQLGSGTF 176
            L KL+ L L +N +  +  +    C NI  +DLS N I  L + ++
Sbjct: 456 ALKKLKCLRLDSNRLTKLDTNELLSCVNISTLDLSNNHITNLSALSY 596
>20775
          Length = 1020

 Score = 34.3 bits (77), Expect = 0.21,   Method: Compositional matrix adjust.
 Identities = 19/45 (42%), Positives = 23/45 (51%)
 Frame = -3

Query: 89  LNLTKNEIGYIEDGAFSGQFNLQVLQLGYNRLRNLTEGMLRGLSK 133
           LNL  N I  IEDG FS    L  L L  N L  +T+    GL++
Sbjct: 283 LNLASNAIDRIEDGFFSRMDKLTTLNLSDNHLSQVTQTTFSGLAQ 149

 Score = 29.3 bits (64), Expect = 6.9,   Method: Compositional matrix adjust.
 Identities = 15/43 (34%), Positives = 21/43 (48%)
 Frame = -3

Query: 64  DLRLNENRIRSVQYASLSRFGNLTYLNLTKNEIGYIEDGAFSG 106
           +L L  N I  ++    SR   LT LNL+ N +  +    FSG
Sbjct: 286 ELNLASNAIDRIEDGFFSRMDKLTTLNLSDNHLSQVTQTTFSG 158
>18260
          Length = 414

 Score = 32.0 bits (71), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 19/57 (33%), Positives = 28/57 (49%), Gaps = 2/57 (3%)
 Frame = +2

Query: 151 AFWECPNIVNIDLSMNRIQQLGSGTFAGLTK--LSVCEIYSNPFYCSCELLGFLRWL 205
           AF    ++  + L  N IQ +   TF+   +  L    +  N F CSC++L F RWL
Sbjct: 2   AFDHMGHLRKLTLDNNYIQTISENTFSPQLRAQLKQLNLGGNHFQCSCDILWFQRWL 172
>19107
          Length = 936

 Score = 30.8 bits (68), Expect = 2.1,   Method: Compositional matrix adjust.
 Identities = 34/119 (28%), Positives = 51/119 (42%), Gaps = 15/119 (12%)
 Frame = -1

Query: 86  LTYLNLTKNEIGYIEDGA------FSGQFNLQVLQLGYNRLRN-----LTEGMLRGLSKL 134
           LTYLNL+ N I    DG             LQ L LGYNRL +     + E +    +KL
Sbjct: 630 LTYLNLSCNRI--TRDGVKELAKVLKQNTALQTLDLGYNRLEDDGAIHIAEALTTLNTKL 457

Query: 135 EYLYLQANLIE----VVMASAFWECPNIVNIDLSMNRIQQLGSGTFAGLTKLSVCEIYS 189
           + L +  N I       +A A      + N+ +  NR+++     F  L K    E+++
Sbjct: 456 QCLVVVHNNIGSAGLCAIADAMKTNTTLTNVYIWGNRLEEPACIAFDNLIKSDRLELFN 280
>02787
          Length = 1090

 Score = 30.8 bits (68), Expect = 2.3,   Method: Compositional matrix adjust.
 Identities = 19/72 (26%), Positives = 30/72 (41%)
 Frame = -1

Query: 196 CELLGFLRWLAAFTNATQTHDRVQCESPPVYAGYFLLGQGRHGHQRSILSKLQSVCTEGS 255
            +++   +W A        H  +Q  + P +  + L+    H H R ILS   ++ T  S
Sbjct: 220 AKVVSIWKWQACIQAGAHVHY*MQTHTYPTHTNHTLIHTHAHTHIRHILSTQANIST--S 47

Query: 256 YTAEVLGPPRPV 267
           Y      PPRP 
Sbjct: 46  Y------PPRPT 29
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|45592932|ref|NP_032971.1| proteasome beta 4 subunit
[Mus musculus]
         (264 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

06516                                                                  37   0.005
15774                                                                  37   0.006
19695                                                                  31   0.55 
07076                                                                  27   9.1  
>06516
          Length = 835

 Score = 37.4 bits (85), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 19/63 (30%), Positives = 34/63 (53%)
 Frame = +1

Query: 50  MVTGTSVLGVKFDGGVVIAADMLGSYGSLARFRNISRIMRVNDSTMLGASGDYADFQYLK 109
           + TGT+++ V+++ GVVI AD   + G+    R   ++ +V D      SG  AD Q + 
Sbjct: 112 VTTGTTIMAVEYEDGVVIGADSRTTTGAYIANRVTDKLTKVTDRIYCCRSGSAADTQAIA 291

Query: 110 QVL 112
            ++
Sbjct: 292 DIV 300
>15774
          Length = 434

 Score = 37.4 bits (85), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 12/22 (54%), Positives = 19/22 (86%)
 Frame = +3

Query: 243 EIEGPLSAQTNWDIAHMISGFE 264
           E+ GP+++Q NW+IAHM+ G+E
Sbjct: 3   EVRGPITSQPNWEIAHMVKGYE 68
>19695
          Length = 568

 Score = 30.8 bits (68), Expect = 0.55,   Method: Compositional matrix adjust.
 Identities = 18/52 (34%), Positives = 28/52 (53%)
 Frame = +3

Query: 38  PCEGPITRTQNPMVTGTSVLGVKFDGGVVIAADMLGSYGSLARFRNISRIMR 89
             E  +   ++ MV G  + G K  GGV++A +MLGS GS    R + +I +
Sbjct: 165 KIETGVLTARDGMVQGMFLTGGKMAGGVLLADEMLGSAGSKIVERVLDKIAK 320
>07076
          Length = 1021

 Score = 26.9 bits (58), Expect = 9.1,   Method: Compositional matrix adjust.
 Identities = 24/84 (28%), Positives = 39/84 (46%), Gaps = 1/84 (1%)
 Frame = -2

Query: 158 GGYADGESFLGYVDMLGVAYEAPSLATGYGAYLAQPLLREVLEKQPV-LSQTEARELVER 216
           GG ADG SFL +++ +        + +   A +  P ++E+LEK P  L + +++   E 
Sbjct: 663 GGEADGNSFLPFMEGM--------MQSLLSAEILLPSIKELLEKYPKYLEENDSKLSAED 508

Query: 217 CMRVLYYKDARSYNRFQIATVTEK 240
             R  Y K    Y   +    TEK
Sbjct: 507 KER--YQKQMELYKVIEGHLQTEK 442
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|46358419|ref|NP_080574.4| intraflagellar transport
172 protein [Mus musculus]
         (1749 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

19498                                                                  41   0.005
20391                                                                  36   0.14 
10313                                                                  35   0.20 
27525                                                                  33   1.1  
12806                                                                  31   4.0  
01892                                                                  31   4.4  
>19498
          Length = 903

 Score = 40.8 bits (94), Expect = 0.005,   Method: Composition-based stats.
 Identities = 31/121 (25%), Positives = 60/121 (49%), Gaps = 3/121 (2%)
 Frame = -1

Query: 3   LKHLRTLLSPQDGAAKVTCMAWSQNNAKFAVCTVDRVVLLYDEHGERRDKFSTKPADMKY 62
           L+H R++ + +  A  V  +AWS  +   A C+VD  +++++       KFS + A ++ 
Sbjct: 648 LEHWRSVATLRGHAGDVLDLAWSPQDLWLASCSVDNTIVVWNAL-----KFSEQVAVIR- 487

Query: 63  GRKSYMVKGMAFSPDSTKIAIGQTDNIIYVYKIGEDWGDKKVICNKFIQ---TSAVTCLQ 119
              + MVKG+ + P    +A    D  + V++   DW ++  + + F +   T+ V  L 
Sbjct: 486 -GHAGMVKGVTWDPVGRYLASQSDDKTLRVWRT-SDWKEETCVKSCFKECGGTTHVLRLN 313

Query: 120 W 120
           W
Sbjct: 312 W 310
>20391
          Length = 582

 Score = 35.8 bits (81), Expect = 0.14,   Method: Compositional matrix adjust.
 Identities = 16/69 (23%), Positives = 37/69 (53%)
 Frame = -1

Query: 594 EGLIEFGTAIDDGNYTRATAFLETLEMTPETEAMWKTLSKLALEARQLHTAERCFSALGH 653
           + ++ F   +  GN   A   ++ ++    +E++W+ ++K+ +++R+L  A  C   +GH
Sbjct: 504 DAMMNFSFHLTTGNMDEAFKSIKLIK----SESVWENMAKMCVKSRRLDVASVCLGNMGH 337

Query: 654 VAKARFLHE 662
              A+ L E
Sbjct: 336 ARGAKALRE 310
>10313
          Length = 689

 Score = 35.4 bits (80), Expect = 0.20,   Method: Compositional matrix adjust.
 Identities = 24/91 (26%), Positives = 45/91 (49%)
 Frame = +3

Query: 638 ARQLHTAERCFSALGHVAKARFLHETNEIADQVSREYGGEGTDFYQVRARLAMLEKNYKL 697
           A+ L+TAE  ++A+  V K +F+    +I  + +R             A +A+L  NY  
Sbjct: 3   AKDLNTAEVAYAAIKEVEKVQFISNIKDIPVKEAR------------NAEMALLCGNYND 146

Query: 698 AEMIFLEQNAVEEAMDMYQELHRWEECIAVA 728
           AE I L+   +  A+ +  +L+ W+  + +A
Sbjct: 147 AEAILLQAGLIFRAVLLNIQLYNWDRALELA 239
>27525
          Length = 828

 Score = 33.1 bits (74), Expect = 1.1,   Method: Composition-based stats.
 Identities = 11/30 (36%), Positives = 21/30 (70%)
 Frame = +2

Query: 69  VKGMAFSPDSTKIAIGQTDNIIYVYKIGED 98
           +  ++FSPD +++A+G  D  ++VY + ED
Sbjct: 77  INAISFSPDGSQLAVGCHDGFVHVYVVHED 166
>12806
          Length = 961

 Score = 31.2 bits (69), Expect = 4.0,   Method: Composition-based stats.
 Identities = 27/107 (25%), Positives = 53/107 (49%), Gaps = 4/107 (3%)
 Frame = +3

Query: 72  MAFSPDSTKIAIGQTDNIIYVYKIGEDWGDKKVICNKFIQTSAVTCLQWPAEY---VIVF 128
           +AFSPD+ +IA G  D  + ++ I    G+ K   +    T  VTC+++  +    ++V 
Sbjct: 309 VAFSPDNRQIASGGRDKNLKIWNI---MGECKYTVDANAHTDWVTCVRFHQDTKNPIVVS 479

Query: 129 GLAEGKVRLANTKT-NKSSTIYGTESYVVALTTNCSGKGILSGHADG 174
              +  +++ +  T    +T  G ++ + AL  + S   ++SG  DG
Sbjct: 480 ASNDKTIKVWDNHTMTLKNTFVGHKAQITAL--DMSTNYLVSGSKDG 614
>01892
          Length = 1672

 Score = 31.2 bits (69), Expect = 4.4,   Method: Composition-based stats.
 Identities = 17/54 (31%), Positives = 26/54 (48%)
 Frame = -2

Query: 482 ISHESRVDWLELNETGHKLLFRDRKLRLHLYDIESCSKTMILNFCSYVQWVPGS 535
           ISHES+ D   + + GH+ +   + L   LY I  C   M  ++  Y+    GS
Sbjct: 501 ISHESKKDTRRIRKNGHRFVLNRQLLLRILYRITKCRTNM*ESYEKYIIETKGS 340
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|27370088|ref|NP_766331.1| pleckstrin homology domain
containing, family A member 7 [Mus musculus]
         (1030 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

03368                                                                  40   0.006
29521                                                                  35   0.22 
18206                                                                  30   4.4  
>03368
          Length = 1677

 Score = 39.7 bits (91), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 45/143 (31%), Positives = 74/143 (51%), Gaps = 12/143 (8%)
 Frame = -2

Query: 895  AAQGD-----RKDKEEGWLKVQATPVMELDLEPQDYDLDISRE-LSKPEKVSIPERYVXX 948
            +A GD     R D     +K   T V ++D   QD    I RE L  PEKV IPERY   
Sbjct: 1349 SAAGDLISNARVDDVPDVVKSSLTNVDKIDQLGQDL---IDREVLYFPEKVLIPERYDAE 1179

Query: 949  XXXXXXXXXXXQARYQKAEKIRNILARSSMCNL-QPLGQDRNSLA-DLDSQLQEQE---- 1002
                         R +KAE+I+ ILA  S+ ++ QP   D N ++ +L ++L++++    
Sbjct: 1178 ADAELLTEDQRVERQEKAERIKRILANQSVLSMSQP---DLNPVSPELHTRLEQEKAQRV 1008

Query: 1003 RIINISYALASEASKRSKQVAAQ 1025
             I+ ++  LA + +++S++ AA+
Sbjct: 1007 HILALNQELARQVTQQSRRAAAE 939
>29521
          Length = 903

 Score = 34.7 bits (78), Expect = 0.22,   Method: Compositional matrix adjust.
 Identities = 14/29 (48%), Positives = 20/29 (68%)
 Frame = +1

Query: 16  EHSGMRTYYFSADTLEDMNAWVRAMNQAA 44
           E  G RTYYF  ++ +DM  WV A+++AA
Sbjct: 142 EKYGARTYYFMTESRDDMTEWVGALSEAA 228
>18206
          Length = 425

 Score = 30.0 bits (66), Expect = 4.4,   Method: Compositional matrix adjust.
 Identities = 23/58 (39%), Positives = 33/58 (56%)
 Frame = -3

Query: 740 VELRSYVSEPELASLSGDVPQPSLSLVGSESRYQTLPGRGLSGSTSRLQQSSTIAPYV 797
           +ELRS+    +LAS+S  V +   SLV +ES+  T P R +S +T     SS  A +V
Sbjct: 300 LELRSWCCRVKLASVSEQV*RSVPSLVMAESQRTTRPFRSVSVAT-WFTSSSFTARFV 130
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6753050|ref|NP_033798.1| bridging integrator 1
isoform 1 [Mus musculus]
         (588 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

12324                                                                  39   0.006
01494                                                                  37   0.016
28095                                                                  35   0.066
29687                                                                  35   0.100
13664                                                                  35   0.11 
08543                                                                  33   0.27 
16716                                                                  33   0.38 
18050                                                                  30   2.4  
>12324
          Length = 946

 Score = 38.9 bits (89), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 23/74 (31%), Positives = 34/74 (45%)
 Frame = +3

Query: 512 LPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKE 571
           +P  ++ KV A +DY A   DEL      V+ VI      + D+GW  GV          
Sbjct: 672 MPATYIEKVVAIYDYEAEKDDELTFSENSVIYVI-----RKNDDGWWEGV---------- 806

Query: 572 LEKCRGVFPENFTE 585
           ++   G+FP N+ E
Sbjct: 807 MDGVTGLFPSNYVE 848
>01494
          Length = 2122

 Score = 37.4 bits (85), Expect = 0.016,   Method: Compositional matrix adjust.
 Identities = 23/74 (31%), Positives = 30/74 (40%), Gaps = 3/74 (4%)
 Frame = +3

Query: 518 FKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWL---MGVKESDWNQHKELEK 574
            +V+A HDY A   DEL    G ++      N   QD GW     G K+  W        
Sbjct: 306 LRVKALHDYNANRDDELSFCKGAII-----TNVSRQDGGWWRGDYGAKKQHW-------- 446

Query: 575 CRGVFPENFTERVQ 588
               FP NF E ++
Sbjct: 447 ----FPSNFVEEIE 476
>28095
          Length = 597

 Score = 35.4 bits (80), Expect = 0.066,   Method: Compositional matrix adjust.
 Identities = 20/68 (29%), Positives = 32/68 (47%)
 Frame = +3

Query: 520 VQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVF 579
            +A +DY A D+DE+    GD ++       +  D GW+ G  E    Q+       G+ 
Sbjct: 264 CKAMYDYQAADSDEVSFNDGDTII-----ECQPVDAGWMTGRVERT-GQY-------GML 404

Query: 580 PENFTERV 587
           P N+ ER+
Sbjct: 405 PSNYVERI 428
>29687
          Length = 434

 Score = 34.7 bits (78), Expect = 0.100,   Method: Compositional matrix adjust.
 Identities = 22/73 (30%), Positives = 29/73 (39%), Gaps = 3/73 (4%)
 Frame = -2

Query: 518 FKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWL---MGVKESDWNQHKELEK 574
            +V+A HDY A   DEL    G ++      N   QD GW     G K+  W        
Sbjct: 298 LRVKALHDYNAKREDELSFCKGAII-----TNVSRQDGGWWRGDYGTKKQHW-------- 158

Query: 575 CRGVFPENFTERV 587
               FP N+ E +
Sbjct: 157 ----FPSNYVEEI 131
>13664
          Length = 507

 Score = 34.7 bits (78), Expect = 0.11,   Method: Compositional matrix adjust.
 Identities = 16/42 (38%), Positives = 25/42 (59%)
 Frame = +2

Query: 519 KVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMG 560
           KV A +DY A  +DEL + +GDV++++      +  E W MG
Sbjct: 368 KVVALYDYKAQRSDELTILSGDVIMLL-----HKDSESWWMG 478
>08543
          Length = 599

 Score = 33.5 bits (75), Expect = 0.27,   Method: Compositional matrix adjust.
 Identities = 13/21 (61%), Positives = 17/21 (80%)
 Frame = +2

Query: 544 VIPFQNPEEQDEGWLMGVKES 564
           VI + +PE+Q+EGWLMG KE 
Sbjct: 5   VIEYDDPEDQEEGWLMGQKEG 67
>16716
          Length = 934

 Score = 32.7 bits (73), Expect = 0.38,   Method: Compositional matrix adjust.
 Identities = 23/72 (31%), Positives = 28/72 (38%)
 Frame = -1

Query: 514 PGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELE 573
           PG      A +DY A D DEL     DV+  I     E  D+GW  G             
Sbjct: 481 PGGGSTAIALYDYQAADDDELTFDPDDVITDI-----EMIDDGWWRGS----------CH 347

Query: 574 KCRGVFPENFTE 585
              G+FP N+ E
Sbjct: 346 GKNGLFPANYVE 311
>18050
          Length = 448

 Score = 30.0 bits (66), Expect = 2.4,   Method: Compositional matrix adjust.
 Identities = 22/69 (31%), Positives = 33/69 (47%)
 Frame = +3

Query: 519 KVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGV 578
           +V A+H Y + + D LQL+ GDVV V       +  +GW  G +  D           G 
Sbjct: 21  QVIAKHSYESDEPDVLQLELGDVVNV-----SRKLPDGWYQGERIRD--------GAVGW 161

Query: 579 FPENFTERV 587
           FP ++TE +
Sbjct: 162 FPGSYTEEL 188
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|87196490|ref|NP_473397.1| PRKC, apoptosis, WT1,
regulator [Mus musculus]
         (333 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

12866                                                                  38   0.006
28612                                                                  28   3.6  
19700                                                                  28   3.9  
19100                                                                  27   9.0  
>12866
          Length = 421

 Score = 38.1 bits (87), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 21/65 (32%), Positives = 50/65 (76%)
 Frame = +1

Query: 268 LEKEVVRERQENLRLVRLMQDKEEMIGKLKEEIDLLNRDLDDMEDENEQLKQENKTLLKV 327
           LE+++ +E++EN +L + ++ K+  I +L+ ++ +LNR+ D+++++N +L++ENK L++ 
Sbjct: 91  LERQLEKEKEENKKLQQQLEQKDRRIAELERQVAMLNRECDELDEDNLKLQEENKALIRA 270

Query: 328 VGQLT 332
           + QL+
Sbjct: 271 MQQLS 285
>28612
          Length = 1740

 Score = 28.5 bits (62), Expect = 3.6,   Method: Compositional matrix adjust.
 Identities = 20/58 (34%), Positives = 29/58 (50%), Gaps = 4/58 (6%)
 Frame = -1

Query: 117 RGDEEEPDSAREKGRSSGPSARKGK----GQIEKRKLREKRRSTGVVNIPAAECLDEY 170
           R  E +    R KGR   P  R+G+      I+ R+ R++RRSTG+  +P    L  Y
Sbjct: 405 RTTERKKKPGRRKGRI--PRNREGREKETAAIKARRKRQERRSTGINYVPVCTTLFSY 238
>19700
          Length = 608

 Score = 28.5 bits (62), Expect = 3.9,   Method: Compositional matrix adjust.
 Identities = 22/57 (38%), Positives = 31/57 (54%)
 Frame = -1

Query: 264 RIEDLEKEVVRERQENLRLVRLMQDKEEMIGKLKEEIDLLNRDLDDMEDENEQLKQE 320
           RI    +E V  R E   L  L    + ++G LK ++  L  D DD++DENE LK+E
Sbjct: 599 RINLCVRECVLLRSEK*ALQNLQSATQGVLGTLKLKMGALKTDNDDLKDENESLKRE 429
>19100
          Length = 768

 Score = 27.3 bits (59), Expect = 9.0,   Method: Compositional matrix adjust.
 Identities = 19/52 (36%), Positives = 27/52 (51%), Gaps = 2/52 (3%)
 Frame = +1

Query: 233 RYPRTDRSGFSRHN--RDANAPASFSSSSTLEKRIEDLEKEVVRERQENLRL 282
           R+P TD    +R +    A   A     S L KRI+ +E E+   R+ENL+L
Sbjct: 493 RHPHTDSPYLARSSSRNKAEVGALKEECSNLRKRIQAIEAEMKMSRKENLQL 648
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31981748|ref|NP_660117.2| ribonuclease/angiogenin
inhibitor 1 [Mus musculus]
         (456 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

01109                                                                  38   0.007
34514                                                                  38   0.010
15500                                                                  37   0.022
28287                                                                  34   0.11 
31609                                                                  33   0.19 
19107                                                                  31   1.3  
39095                                                                  29   4.7  
>01109
          Length = 2130

 Score = 38.1 bits (87), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 30/110 (27%), Positives = 49/110 (44%), Gaps = 2/110 (1%)
 Frame = +3

Query: 196 LESLKLENCGITAANCKDLCDVVASKASLQELDLSSNKLGNAGIAALCPGLLLPSCK-LR 254
           LE L +   GI       L + +A    L+ L+L+ N     G   +    +LP  + L 
Sbjct: 459 LEELAMPQNGINLPGITALVEAIAVNTKLRVLNLNDNTFTETGSHEMAK--VLPKLQELE 632

Query: 255 TLWLWECDITAEGCKDLCRVLR-AKQSLKELSLASNELKDEGARLLCESL 303
            +   +C +   G   +   ++  +  LKEL L+ NE+K  GA  + ESL
Sbjct: 633 VINFGDCLLRTGGALAIADAVKDGQHKLKELILSGNEIKQNGAVAITESL 782
>34514
          Length = 1178

 Score = 37.7 bits (86), Expect = 0.010,   Method: Compositional matrix adjust.
 Identities = 28/88 (31%), Positives = 42/88 (47%)
 Frame = -3

Query: 271 LCRVLRAKQSLKELSLASNELKDEGARLLCESLLEPGCQLESLWIKTCSLTAASCPYFCS 330
           L R       +  L+L  NE  DEG + LC+  L     L S+ +  C L  AS  Y  S
Sbjct: 432 LARSFVFCDQMTTLNLDYNEFGDEGVKYLCDG-LRNNTTLLSISLCYCDLGVASGTYLGS 256

Query: 331 VLTKSRSLLELQMSSNPLGDEGVQELCK 358
           +++ + ++ EL +  N L  EG  E+ K
Sbjct: 255 IVSTT-AVRELYLDGNNLQCEGTMEMIK 175
>15500
          Length = 550

 Score = 36.6 bits (83), Expect = 0.022,   Method: Compositional matrix adjust.
 Identities = 32/94 (34%), Positives = 44/94 (46%), Gaps = 3/94 (3%)
 Frame = +2

Query: 213 DLCDVVASKASLQELDLSSNKLGNAGIAALCPGLLLPSC---KLRTLWLWECDITAEGCK 269
           +L D++   + L+ L L    L N+  A     L   S    KL TL L    IT  G  
Sbjct: 137 NLSDLINLHSPLENLSLRFCGLTNSNAAGFGRALGTLSTWNKKLLTLNLSHNSITDLGVS 316

Query: 270 DLCRVLRAKQSLKELSLASNELKDEGARLLCESL 303
            L   L   ++L  L+LASN++ DEGA  L + L
Sbjct: 317 HLAHGLMTNRTLLVLNLASNQIGDEGAAALAQVL 418

 Score = 35.4 bits (80), Expect = 0.051,   Method: Compositional matrix adjust.
 Identities = 35/114 (30%), Positives = 50/114 (43%), Gaps = 5/114 (4%)
 Frame = +2

Query: 309 QLESLWIKTCSLTAASCPYFCSVLTKSRSLLELQMSSNPL-GDEGVQELCKALSQPDTVL 367
           QL ++ +    LTA +       L +  SL  L + +NPL GD  + +L   L  P   L
Sbjct: 5   QLTTMQLWNTGLTAQTIDMLAYFLPRCHSLTTLLLDANPLIGDANLSDLIN-LHSP---L 172

Query: 368 RELWLGDCDVTNSGCSSLANVLLA----NRSLRELDLSNNCMGGPGVLQLLESL 417
             L L  C +TNS  +     L      N+ L  L+LS+N +   GV  L   L
Sbjct: 173 ENLSLRFCGLTNSNAAGFGRALGTLSTWNKKLLTLNLSHNSITDLGVSHLAHGL 334

 Score = 28.5 bits (62), Expect = 5.5,   Method: Compositional matrix adjust.
 Identities = 21/60 (35%), Positives = 30/60 (50%), Gaps = 4/60 (6%)
 Frame = +2

Query: 77  NPTCKIQKLSLQNCGLTEAGCGILPGMLRSLST----LRELHLNDNPMGDAGLKLLCEGL 132
           N    ++ LSL+ CGLT +        L +LST    L  L+L+ N + D G+  L  GL
Sbjct: 155 NLHSPLENLSLRFCGLTNSNAAGFGRALGTLSTWNKKLLTLNLSHNSITDLGVSHLAHGL 334
>28287
          Length = 1383

 Score = 34.3 bits (77), Expect = 0.11,   Method: Compositional matrix adjust.
 Identities = 20/58 (34%), Positives = 30/58 (51%)
 Frame = +2

Query: 362 QPDTVLRELWLGDCDVTNSGCSSLANVLLANRSLRELDLSNNCMGGPGVLQLLESLKQ 419
           Q +  L+  ++    V NSGC  + +VL  NRSL E D+S   M   GV  +   L++
Sbjct: 5   QENVGLKYFYMPMAGVGNSGCVLIGDVLKNNRSLLEFDVSYCRMPVNGVTHVASGLRE 178
>31609
          Length = 841

 Score = 33.5 bits (75), Expect = 0.19,   Method: Compositional matrix adjust.
 Identities = 24/74 (32%), Positives = 40/74 (54%)
 Frame = +1

Query: 358 KALSQPDTVLRELWLGDCDVTNSGCSSLANVLLANRSLRELDLSNNCMGGPGVLQLLESL 417
            A SQ +  L+ L L +  + + GC +   +L  N +L ELD+++N +   G++ L  ++
Sbjct: 343 HAWSQGNLCLKRLLLANNGIGDPGCMAAGEMLANNSTLLELDIASNRVLDSGLVALANNI 522

Query: 418 KQPSCTLQQLVLYD 431
           K    TLQ L L D
Sbjct: 523 KHNE-TLQTLKLGD 561

 Score = 26.2 bits (56), Expect(2) = 0.55,   Method: Compositional matrix adjust.
 Identities = 24/103 (23%), Positives = 47/103 (45%)
 Frame = +1

Query: 167 FKELVLSNNDLHEPGVRILCQGLKDSACQLESLKLENCGITAANCKDLCDVVASKASLQE 226
            K L+L+NN + +PG                             C    +++A+ ++L E
Sbjct: 370 LKRLLLANNGIGDPG-----------------------------CMAAGEMLANNSTLLE 462

Query: 227 LDLSSNKLGNAGIAALCPGLLLPSCKLRTLWLWECDITAEGCK 269
           LD++SN++ ++G+ AL    +  +  L+TL L +   T +G +
Sbjct: 463 LDIASNRVLDSGLVALANN-IKHNETLQTLKLGDNLATGKGAQ 588

 Score = 24.3 bits (51), Expect(2) = 0.55,   Method: Compositional matrix adjust.
 Identities = 19/79 (24%), Positives = 29/79 (36%)
 Frame = +2

Query: 82  IQKLSLQNCGLTEAGCGILPGMLRSLSTLRELHLNDNPMGDAGLKLLCEGLQDPQCRLEK 141
           +Q +SL   G  +        ++     LREL L+ N + D       EGL +       
Sbjct: 119 LQSVSLAGNGFKDTDAVNFTQVIMDRRPLRELDLSHNELSDGAAVQFGEGLVNNDI---- 286

Query: 142 LQLEYCNLTATSCEPLASV 160
             LE  +L+     P   V
Sbjct: 287 --LEVLDLSWNHIRPRGGV 337

 Score = 27.7 bits (60), Expect = 9.4,   Method: Compositional matrix adjust.
 Identities = 21/63 (33%), Positives = 35/63 (55%)
 Frame = +1

Query: 82  IQKLSLQNCGLTEAGCGILPGMLRSLSTLRELHLNDNPMGDAGLKLLCEGLQDPQCRLEK 141
           +++L L N G+ + GC     ML + STL EL +  N + D+GL  L   ++  +  L+ 
Sbjct: 370 LKRLLLANNGIGDPGCMAAGEMLANNSTLLELDIASNRVLDSGLVALANNIKHNET-LQT 546

Query: 142 LQL 144
           L+L
Sbjct: 547 LKL 555
>19107
          Length = 936

 Score = 30.8 bits (68), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 18/51 (35%), Positives = 28/51 (54%)
 Frame = -1

Query: 351 EGVQELCKALSQPDTVLRELWLGDCDVTNSGCSSLANVLLANRSLRELDLS 401
           +G     +AL Q +T L  L LGD D+      +L  VLL N +LR ++++
Sbjct: 936 KGGMYFAQAL-QINTTLEHLDLGDTDLRTESLIALGTVLLHNVTLRSININ 787
>39095
          Length = 505

 Score = 28.9 bits (63), Expect = 4.7,   Method: Compositional matrix adjust.
 Identities = 18/45 (40%), Positives = 25/45 (55%)
 Frame = -2

Query: 89  NCGLTEAGCGILPGMLRSLSTLRELHLNDNPMGDAGLKLLCEGLQ 133
           +C +TEAG GI+PG L+  + LR       P   AGL+   + LQ
Sbjct: 147 HCSVTEAGPGIMPGALQH-TLLRIQQQCPYPRTAAGLESHVKSLQ 16
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31712002|ref|NP_853625.1| cDNA sequence BC022641 [Mus
musculus]
         (1390 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

19949                                                                  40   0.008
17602                                                                  35   0.23 
12574                                                                  34   0.33 
27270                                                                  33   0.73 
21921                                                                  33   0.91 
27525                                                                  33   1.0  
14500                                                                  32   1.7  
19140                                                                  32   1.9  
30176                                                                  31   3.0  
13335                                                                  30   6.5  
02147                                                                  30   7.3  
14555                                                                  30   9.3  
>19949
          Length = 903

 Score = 39.7 bits (91), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 17/40 (42%), Positives = 22/40 (55%)
 Frame = +2

Query: 287 KQGFIVVKGHSTCLSEGALSPDGTVLATASHDGFVKFWQI 326
           K      KGH+ C+     SPDG  +A+AS DG VK W +
Sbjct: 89  KGCIYTYKGHTGCVCCLRFSPDGRWIASASEDGLVKLWDL 208
>17602
          Length = 481

 Score = 35.0 bits (79), Expect = 0.23,   Method: Composition-based stats.
 Identities = 37/155 (23%), Positives = 61/155 (39%), Gaps = 4/155 (2%)
 Frame = +3

Query: 295 GHSTCLSEGALSPDGTVLATASHDGFVKFWQIYIEGQDEPRCLHEWKPHDGRPLSCLLFC 354
            HS  ++    + DG+++ ++S+DG  + W     GQ    CL      D  P+S + F 
Sbjct: 48  AHSDPVTAVHFNRDGSLIVSSSYDGLCRIWDT-ASGQ----CLXTLIDDDNPPVSFVKFS 212

Query: 355 DNHKKQDPEVPFWRFLITGADQNRELKMWCTVSWTCLQTIRFSPD----IFSSVSVPPSL 410
            N K            I  A  +  LK+W      CL+T     +    IF++ SV    
Sbjct: 213 PNGK-----------YILAATLDNTLKLWDYSKGKCLKTYVGHRNEKYCIFANFSV---- 347

Query: 411 KVCLDLSAEYLILSDVQRKVLYVMELLQNQDEGRA 445
                 +    I+S  +  ++Y+  LL   D   A
Sbjct: 348 ------TGGKWIVSGSEDNMVYIWNLLDQGDSTEA 434
>12574
          Length = 521

 Score = 34.3 bits (77), Expect = 0.33,   Method: Composition-based stats.
 Identities = 28/103 (27%), Positives = 46/103 (44%)
 Frame = +3

Query: 293 VKGHSTCLSEGALSPDGTVLATASHDGFVKFWQIYIEGQDEPRCLHEWKPHDGRPLSCLL 352
           + GH+  LS    SP+G  LA++S D  +K W  Y +G+ E       K   G  L    
Sbjct: 174 LAGHTKALSAVKFSPNGDWLASSSADKLIKIWGAY-DGKFE-------KTIAGHKLG--- 320

Query: 353 FCDNHKKQDPEVPFWRFLITGADQNRELKMWCTVSWTCLQTIR 395
             D     D +      L+  A  ++ LK+W   +  C++T++
Sbjct: 321 LSDVAWSSDSK------LLCSASDDKTLKIWEFSTGKCMKTLK 431

 Score = 31.6 bits (70), Expect = 2.1,   Method: Composition-based stats.
 Identities = 21/68 (30%), Positives = 30/68 (44%)
 Frame = +3

Query: 293 VKGHSTCLSEGALSPDGTVLATASHDGFVKFWQIYIEGQDEPRCLHEWKPHDGRPLSCLL 352
           + GH   LS+ A S D  +L +AS D  +K W+         +C+   K H     S  +
Sbjct: 300 IAGHKLGLSDVAWSSDSKLLCSASDDKTLKIWEF-----STGKCMKTLKGH-----SNYV 449

Query: 353 FCDNHKKQ 360
           FC N   Q
Sbjct: 450 FCCNFNPQ 473
>27270
          Length = 1078

 Score = 33.1 bits (74), Expect = 0.73,   Method: Compositional matrix adjust.
 Identities = 20/78 (25%), Positives = 34/78 (43%), Gaps = 4/78 (5%)
 Frame = +2

Query: 294 KGHSTCLSEGALSPDGTVLATASHDGFVKFWQIYIEGQDEPRCLHEWKPHDGR--PLSCL 351
           KGHS  +++     DG  L ++S DG V  W +     +    + +WK   GR   + C+
Sbjct: 263 KGHSKAVTDMCWRADGRTLYSSSLDGHVIGWNV-----NTLHMIEKWKATSGRHHGVHCV 427

Query: 352 LFCDNHK--KQDPEVPFW 367
             C + +    D  +  W
Sbjct: 428 CLCSSSRLLTADHTIKMW 481
>21921
          Length = 1341

 Score = 33.1 bits (74), Expect = 0.91,   Method: Compositional matrix adjust.
 Identities = 12/36 (33%), Positives = 20/36 (55%)
 Frame = -1

Query: 291 IVVKGHSTCLSEGALSPDGTVLATASHDGFVKFWQI 326
           +V KGH+  +      P G  L + S DG ++FW++
Sbjct: 501 LVYKGHTGIVRSICPDPTGQWLVSGSDDGTIRFWEV 394
>27525
          Length = 828

 Score = 32.7 bits (73), Expect = 1.0,   Method: Composition-based stats.
 Identities = 31/117 (26%), Positives = 44/117 (37%), Gaps = 12/117 (10%)
 Frame = +2

Query: 304 ALSPDGTVLATASHDGFVKFWQIYIEG-----------QDEPRCLH-EWKPHDGRPLSCL 351
           + SPDG+ LA   HDGFV  + ++ +G            +    +H +W   D R L C 
Sbjct: 89  SFSPDGSQLAVGCHDGFVHVYVVHEDGLVFRQKSAALRYNSTFIMHLDWSS-DCRYLQCT 265

Query: 352 LFCDNHKKQDPEVPFWRFLITGADQNRELKMWCTVSWTCLQTIRFSPDIFSSVSVPP 408
           L        D E+ FW          R L+    V+W+            S V  PP
Sbjct: 266 L-------GDYELVFWEVQNMKKQSGRALR---DVNWSTFS---------SPVGYPP 379
>14500
          Length = 1238

 Score = 32.0 bits (71), Expect = 1.7,   Method: Composition-based stats.
 Identities = 15/51 (29%), Positives = 25/51 (49%)
 Frame = +2

Query: 293 VKGHSTCLSEGALSPDGTVLATASHDGFVKFWQIYIEGQDEPRCLHEWKPH 343
           + GHS  +     SPDG  LA+ ++D  +  W   + G +  + LH +  H
Sbjct: 47  LSGHSQEVCGLRWSPDGKYLASGANDNLLCVWPAQVTGGNSTQPLHTFSQH 199
>19140
          Length = 573

 Score = 32.0 bits (71), Expect = 1.9,   Method: Compositional matrix adjust.
 Identities = 17/55 (30%), Positives = 29/55 (52%)
 Frame = -3

Query: 290 FIVVKGHSTCLSEGALSPDGTVLATASHDGFVKFWQIYIEGQDEPRCLHEWKPHD 344
            + +KGH+  +    L+ DGT   + S DG ++ W +   GQ   RC+  ++ HD
Sbjct: 508 LMKLKGHTDNVKALVLNRDGTQCLSGSSDGTIRLWSL---GQQ--RCVATFRVHD 359
>30176
          Length = 365

 Score = 31.2 bits (69), Expect = 3.0,   Method: Composition-based stats.
 Identities = 14/41 (34%), Positives = 21/41 (51%)
 Frame = +2

Query: 293 VKGHSTCLSEGALSPDGTVLATASHDGFVKFWQIYIEGQDE 333
           +K H++ +        GT LA+ S D  +K WQ Y+ G  E
Sbjct: 8   LKSHTSTVWNLTFDKTGTRLASCSDDKTIKIWQEYLPGNPE 130
>13335
          Length = 863

 Score = 30.0 bits (66), Expect = 6.5,   Method: Composition-based stats.
 Identities = 14/37 (37%), Positives = 22/37 (59%)
 Frame = +1

Query: 290 FIVVKGHSTCLSEGALSPDGTVLATASHDGFVKFWQI 326
           F +   HS  ++  A S DGT+LA+ S D  +K W++
Sbjct: 616 FSIEACHSRFVTCCAFSIDGTLLASGSMDRIIKIWKL 726
>02147
          Length = 1547

 Score = 30.0 bits (66), Expect = 7.3,   Method: Compositional matrix adjust.
 Identities = 14/36 (38%), Positives = 19/36 (52%)
 Frame = +2

Query: 293 VKGHSTCLSEGALSPDGTVLATASHDGFVKFWQIYI 328
            KGH   +     SPDG + A+ S DG ++ WQ  I
Sbjct: 782 FKGHFGPVHCVRFSPDGELYASGSEDGTLRLWQTTI 889
>14555
          Length = 627

 Score = 29.6 bits (65), Expect = 9.3,   Method: Composition-based stats.
 Identities = 17/50 (34%), Positives = 26/50 (52%), Gaps = 2/50 (4%)
 Frame = -3

Query: 277 NTWPVDVSQIKQGF--IVVKGHSTCLSEGALSPDGTVLATASHDGFVKFW 324
           N + V+V    +G    ++ GH   +S   +SPDGT L T S D  ++ W
Sbjct: 406 NDYTVNVWDALKGMRSTILYGHDNRVSCLRISPDGTSLCTGSWDYTLRIW 257
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|29789423|ref|NP_780534.1| Bardet-Biedl syndrome 4
homolog [Mus musculus]
         (520 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

08670                                                                  38   0.010
28154                                                                  37   0.024
34628                                                                  36   0.045
>08670
          Length = 1307

 Score = 38.1 bits (87), Expect = 0.010,   Method: Compositional matrix adjust.
 Identities = 24/84 (28%), Positives = 35/84 (41%)
 Frame = +3

Query: 286 YVAAISCLKRANYLAPFDWKILYNLGLVHLTMQQYASAFHFLSAAINFQPKMGELYMLLA 345
           Y AAI     A  L P D++ L N    +  +QQY  A      AI       + Y    
Sbjct: 420 YSAAIQLFTEAIALDPKDFRFLGNRSYCYDRLQQYEKALKDAEKAIKLSKDWPKGYFRKG 599

Query: 346 VALTNLEDIENARRAYVEAVRLDK 369
            AL  L     A  ++++ ++LDK
Sbjct: 600 RALAGLCKFSEAEESFLQVLKLDK 671
>28154
          Length = 374

 Score = 36.6 bits (83), Expect = 0.024,   Method: Compositional matrix adjust.
 Identities = 24/74 (32%), Positives = 37/74 (50%), Gaps = 1/74 (1%)
 Frame = +1

Query: 127 AAKLNQKDWEICHNLGVCYTYLKQFNKAQDQLHSALQLNKHD-LTYIMLGKIHLLQGDLD 185
           AA     D ++  NLGV +    ++NKA D   +ALQ    D L +  LG      G  +
Sbjct: 70  AAPQESVDADVQCNLGVLFNLSGEYNKAVDCFQAALQARPKDALLWNKLGATLANGGRSE 249

Query: 186 KAIEIYKKAVEFSP 199
           +A++ Y  A++ SP
Sbjct: 250 EAVDAYHNALQLSP 291

 Score = 30.0 bits (66), Expect = 2.1,   Method: Compositional matrix adjust.
 Identities = 17/75 (22%), Positives = 33/75 (44%)
 Frame = +1

Query: 243 GSMMQTHGDFDVALTKYRVVACAIPESPPLWNNIGMCFFGKKKYVAAISCLKRANYLAPF 302
           G +    G+++ A+  ++    A P+   LWN +G       +   A+     A  L+P 
Sbjct: 115 GVLFNLSGEYNKAVDCFQAALQARPKDALLWNKLGATLANGGRSEEAVDAYHNALQLSPG 294

Query: 303 DWKILYNLGLVHLTM 317
             +  YNLG+  + +
Sbjct: 295 FIRSRYNLGIACINL 339
>34628
          Length = 545

 Score = 35.8 bits (81), Expect = 0.045,   Method: Compositional matrix adjust.
 Identities = 21/56 (37%), Positives = 33/56 (58%), Gaps = 2/56 (3%)
 Frame = +1

Query: 147 YLKQFNKAQDQLHSALQLNKHDLTYIM--LGKIHLLQGDLDKAIEIYKKAVEFSPE 200
           YL+Q    QD L   +   K DL   +  LG++H + GD+DKAIE Y+++++   E
Sbjct: 37  YLEQARDIQDVLEEDI---KGDLVSTLHQLGQMHTMAGDIDKAIESYRESLDVFRE 195
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|30520065|ref|NP_848794.1| zinc finger protein 365
[Mus musculus]
         (408 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

18798                                                                  38   0.010
00382                                                                  30   2.2  
13512                                                                  30   2.2  
03292                                                                  29   4.2  
>18798
          Length = 461

 Score = 37.7 bits (86), Expect = 0.010,   Method: Compositional matrix adjust.
 Identities = 13/31 (41%), Positives = 22/31 (70%)
 Frame = -1

Query: 24  LPFRCPRCGDHTRFRSLSSLRAHLEFSHSYE 54
           +P+RCPRCG    F +L+ L++H+   H+Y+
Sbjct: 155 VPYRCPRCGGSRTFNTLAELKSHMAEEHAYQ 63
>00382
          Length = 808

 Score = 29.6 bits (65), Expect = 2.2,   Method: Compositional matrix adjust.
 Identities = 16/40 (40%), Positives = 18/40 (45%)
 Frame = -3

Query: 283 VELAEKQLEYYQSQQASGFSCDTSEHMLTDIPSNRKPRCL 322
           V L E+    Y  QQAS        HMLT +P    P CL
Sbjct: 236 VGLLEEFAHLYSHQQASAIVFSPVRHMLTKLPLTCYPHCL 117
>13512
          Length = 1552

 Score = 29.6 bits (65), Expect = 2.2,   Method: Compositional matrix adjust.
 Identities = 16/40 (40%), Positives = 18/40 (45%)
 Frame = +3

Query: 283 VELAEKQLEYYQSQQASGFSCDTSEHMLTDIPSNRKPRCL 322
           V L E+    Y  QQAS        HMLT +P    P CL
Sbjct: 510 VGLLEEFAHLYSHQQASAIVFSPVRHMLTKLPLTCYPHCL 629
>03292
          Length = 1176

 Score = 28.9 bits (63), Expect = 4.2,   Method: Compositional matrix adjust.
 Identities = 12/42 (28%), Positives = 19/42 (45%)
 Frame = -1

Query: 322  LSRGHQHSVCNHPEMRAHFHLKGRSYLKKAKDERAGMQPAKA 363
            LS  H+H  C H  M AH H    +  ++AK  +     + +
Sbjct: 1140 LSNTHRHVTCTHTRMHAHTHTHMSTTYRQAKRHKVAYNSSNS 1015
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|148747198|ref|NP_038770.3| cysteinyl-tRNA synthetase
[Mus musculus]
         (831 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

15076                                                                  39   0.011
07453                                                                  35   0.087
30154                                                                  35   0.16 
27441                                                                  31   2.1  
10621                                                                  31   2.4  
23211                                                                  30   2.8  
11936                                                                  30   4.3  
>15076
          Length = 2760

 Score = 38.5 bits (88), Expect = 0.011,   Method: Compositional matrix adjust.
 Identities = 34/122 (27%), Positives = 54/122 (44%), Gaps = 2/122 (1%)
 Frame = +2

Query: 443 MDIHGGGFDLRFPHHDNELAQSEAYFENDC--WVRYFLHTGHLTIAGCKMSKSLKNFITI 500
           +D+   G DL   H    +    A + ND   W +     GH+ +   KMSKS  NF+T+
Sbjct: 731 VDVRMSGKDLIQNHLTYFIYCHTAMWPNDKSKWPKGIRANGHILLNSEKMSKSTGNFLTL 910

Query: 501 KDALKKHSARQLRLAFLMHSWKDTLDYSSNTMESALQYEKFMNEFFLNVKDILRAPVDIT 560
            DA+ K SA  +R          +L  + +T+E A   EK  +   L +  +L    ++ 
Sbjct: 911 YDAVDKFSADGMRF---------SLADAGDTVEDANFVEKMADAGLLRLYTLLEWVREMA 1063

Query: 561 GQ 562
            Q
Sbjct: 1064AQ 1069
>07453
          Length = 510

 Score = 35.4 bits (80), Expect = 0.087,   Method: Composition-based stats.
 Identities = 17/44 (38%), Positives = 25/44 (56%)
 Frame = -3

Query: 473 WVRYFLHTGHLTIAGCKMSKSLKNFITIKDALKKHSARQLRLAF 516
           W +     GH+ +   KMSKS  NF+T+ DA+ K SA  +R + 
Sbjct: 490 WPKGIRANGHILLNSEKMSKSTGNFLTLYDAVDKFSADGMRFSL 359
>30154
          Length = 584

 Score = 34.7 bits (78), Expect = 0.16,   Method: Composition-based stats.
 Identities = 20/41 (48%), Positives = 22/41 (53%), Gaps = 1/41 (2%)
 Frame = -3

Query: 445 IHGGGFDLRFPHHDNELAQSEAYFENDCWVRYFLHT-GHLT 484
           IHGG  DL+  HH  EL Q  A  + DC V   LH   HLT
Sbjct: 570 IHGGVADLKRAHHQPELGQGVAQEQLDCGVGLVLHNLLHLT 448
>27441
          Length = 388

 Score = 30.8 bits (68), Expect = 2.1,   Method: Composition-based stats.
 Identities = 15/48 (31%), Positives = 27/48 (56%)
 Frame = +2

Query: 569 EEVELNKNFYGKKTAVHEALCDNIDTRTVMEEMRALVSQCNLYMAARK 616
           ++V+L++   GK+TA+   LC   D+    E+ R     C + +AAR+
Sbjct: 77  KQVQLDRCEAGKRTALDSQLCAVRDSDAGAEQFRECCHCCQMGVAARR 220
>10621
          Length = 1304

 Score = 30.8 bits (68), Expect = 2.4,   Method: Compositional matrix adjust.
 Identities = 16/53 (30%), Positives = 28/53 (52%), Gaps = 7/53 (13%)
 Frame = +2

Query: 28  LDQHLSTRSYIQGYSLSQADVD-------VFRQLSAPPADSRLFHVARWFRHI 73
           L+ +L TR+Y+ G S++QAD+        ++ Q+  P       +V RWF  +
Sbjct: 428 LNDYLLTRTYLVGESVTQADISLACNLIMLYEQVMDPEFRKPFQNVNRWFTTL 586
>23211
          Length = 1156

 Score = 30.4 bits (67), Expect = 2.8,   Method: Compositional matrix adjust.
 Identities = 16/56 (28%), Positives = 29/56 (51%), Gaps = 7/56 (12%)
 Frame = +1

Query: 25 VQALDQHLSTRSYIQGYSLSQADVD-------VFRQLSAPPADSRLFHVARWFRHI 73
          +  L+ +L TR+Y+ G S++QAD+        ++ Q+  P       +V RWF  +
Sbjct: 1  LTVLNDYLLTRTYLVGESVTQADISLACNLIMLYEQVMDPEFRKPFQNVNRWFXTL 168
>11936
          Length = 1788

 Score = 30.0 bits (66), Expect = 4.3,   Method: Composition-based stats.
 Identities = 11/33 (33%), Positives = 19/33 (57%)
 Frame = +3

Query: 147  HMGHARSYISFDILRRVLRDYFQYDVFYCMNIT 179
            H+GH+ +  S      +++D F+   FYC N+T
Sbjct: 1641 HLGHSHNTFSILTGS*IMKDLFELLAFYCCNVT 1739
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|26986595|ref|NP_758485.1| ring finger protein 40 [Mus
musculus]
         (1001 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

14716                                                                  39   0.011
14159                                                                  38   0.021
33436                                                                  35   0.17 
07854                                                                  34   0.27 
09545                                                                  34   0.35 
27368                                                                  32   1.1  
20704                                                                  30   3.4  
29117                                                                  30   3.5  
05665                                                                  30   3.5  
20109                                                                  29   8.0  
02016                                                                  29   9.7  
>14716
          Length = 481

 Score = 38.9 bits (89), Expect = 0.011,   Method: Composition-based stats.
 Identities = 18/63 (28%), Positives = 29/63 (46%)
 Frame = +2

Query: 931 ADEILQEEIKEYKARLTCPCCNTRKKDAVLTKCFHVFCFECVRGRYEARQRKCPKCNAAF 990
           A  I  E+       L C  C   ++   LT C H+FC++C+  ++   + +CP C   F
Sbjct: 101 AGGISSEDSASLPPSLKCSLCLGPRRRTTLTVCGHLFCWDCIH-QWCQEKAECPLCREQF 277

Query: 991 GAH 993
             H
Sbjct: 278 PPH 286
>14159
          Length = 618

 Score = 37.7 bits (86), Expect = 0.021,   Method: Composition-based stats.
 Identities = 15/38 (39%), Positives = 22/38 (57%), Gaps = 6/38 (15%)
 Frame = +2

Query: 955 KKDAVLTKCFHVFCFECVRGRYEARQ------RKCPKC 986
           K+  +L  C H+FC EC+R   +A+Q      R CP+C
Sbjct: 74  KRFGILPNCNHIFCLECIRKWRQAKQFEHKITRACPEC 187
>33436
          Length = 583

 Score = 35.0 bits (79), Expect = 0.17,   Method: Composition-based stats.
 Identities = 20/57 (35%), Positives = 24/57 (42%), Gaps = 1/57 (1%)
 Frame = -1

Query: 935 LQEEIKEYKARLTCPCCNTRKKDAVLTKCFHVFCFECVRGRYE-ARQRKCPKCNAAF 990
           +QE I   +  L C  C       V TKC H FC  C+    E  R   CP C A +
Sbjct: 439 IQELIGLMQKNLECSICLELMTSPVATKCEHYFCRFCITEFLEKKRSVPCPLCKATY 269
>07854
          Length = 1752

 Score = 34.3 bits (77), Expect = 0.27,   Method: Compositional matrix adjust.
 Identities = 17/60 (28%), Positives = 28/60 (46%), Gaps = 6/60 (10%)
 Frame = -1

Query: 944  ARLTCPCC-NT-----RKKDAVLTKCFHVFCFECVRGRYEARQRKCPKCNAAFGAHDFHR 997
             ++TCP C +T     R ++   T C H+FC  C++   ++ Q  CP C         H+
Sbjct: 1026 VKVTCPVCLDTDAQIRRNRELYSTMCGHIFCSACIKQAIDS-QHACPTCRXKLTKRQIHK 850
>09545
          Length = 1614

 Score = 33.9 bits (76), Expect = 0.35,   Method: Compositional matrix adjust.
 Identities = 20/73 (27%), Positives = 42/73 (57%)
 Frame = -1

Query: 838  LQGSLGGVEKELTLRSQALELNKRKAVEAAQLAEDLKVQLEHVQTRLREIQPCLAESRAA 897
            L+  L   E E+ +++ ++   +R   E  +  +DL +Q++H+Q RLR     + ++R++
Sbjct: 1434 LKRDLATAEDEVDMQTNSVRRMQRSNDELQEQVDDLTLQVDHLQNRLRRGSQSIPKTRSS 1255

Query: 898  REKESFNLKRAQE 910
              K SFN++ + E
Sbjct: 1254 SLK-SFNMEDSAE 1219
>27368
          Length = 394

 Score = 32.3 bits (72), Expect = 1.1,   Method: Composition-based stats.
 Identities = 15/40 (37%), Positives = 21/40 (52%)
 Frame = +1

Query: 946 LTCPCCNTRKKDAVLTKCFHVFCFECVRGRYEARQRKCPK 985
           L C  C+    D + TKC H FC  C++  + A Q  CP+
Sbjct: 4   LLCQLCHQPLVDPLETKCGHTFCTSCLKS-HLAVQALCPE 120
>20704
          Length = 874

 Score = 30.4 bits (67), Expect = 3.4,   Method: Composition-based stats.
 Identities = 13/46 (28%), Positives = 19/46 (41%), Gaps = 2/46 (4%)
 Frame = -1

Query: 943 KARLTCPCCNTRKKDAVLTKCFHVFCFECVRGRYE--ARQRKCPKC 986
           K+   CP C+       +  C H  C +C+    +   R R CP C
Sbjct: 349 KSEFECPVCHEDYDQHKILPCKHTACHKCILTWLQKGGRNRGCPLC 212
>29117
          Length = 320

 Score = 30.4 bits (67), Expect = 3.5,   Method: Composition-based stats.
 Identities = 15/46 (32%), Positives = 19/46 (41%), Gaps = 5/46 (10%)
 Frame = +1

Query: 946 LTCPCCNTRKKDAVLTKCFHVFCFECVRGRYEAR-----QRKCPKC 986
           LTCP C     +  +  C H FC  C+R   +       Q  CP C
Sbjct: 70  LTCPLCLQLFTEPKILPCQHTFCSHCLRKYLDHNTFLQWQCVCPLC 207
>05665
          Length = 1610

 Score = 30.4 bits (67), Expect = 3.5,   Method: Compositional matrix adjust.
 Identities = 20/80 (25%), Positives = 43/80 (53%), Gaps = 9/80 (11%)
 Frame = -3

Query: 213 VYSRGDSEAPGEV---ARVRTRELGRENRRLQDLATQLQEKHHRISLEYSELQDKVT--- 266
           VYS+ +S +  EV   + +    +G++   ++    ++ E+H ++ +E++E QDK+T   
Sbjct: 444 VYSKANSVSTSEVMAPSWLHRFIIGKKGANIR----RITEEHPKVHIEFTEGQDKITVEG 277

Query: 267 ---STETKVLEMETTVEDLQ 283
                +  +L +E  V DL+
Sbjct: 276 SPEEVQEAILALEVIVTDLK 217
>20109
          Length = 418

 Score = 29.3 bits (64), Expect = 8.0,   Method: Compositional matrix adjust.
 Identities = 15/47 (31%), Positives = 20/47 (42%), Gaps = 3/47 (6%)
 Frame = -1

Query: 943 KARLTCPCCNTRKKDAVLTKCFHVFCFEC---VRGRYEARQRKCPKC 986
           K R+TC  C    +D     C H FC +C   +  R  +    CP C
Sbjct: 346 KERVTCTVCFEVFRDPRFLPCHHTFCLQCLADLASRSPSSTFPCPVC 206
>02016
          Length = 3061

 Score = 28.9 bits (63), Expect = 9.7,   Method: Compositional matrix adjust.
 Identities = 29/81 (35%), Positives = 47/81 (58%), Gaps = 7/81 (8%)
 Frame = +3

Query: 870 AEDLKVQLEHV--QTRLREIQPCLAESRAAREKESFNLKRAQED--ISRLRRKLEKQRKV 925
           A+DL  +L  +  +T   E++    ES+ ARE+E F L+ AQ+D  ++ LR  LE+Q  +
Sbjct: 519 ADDLGAELAKLKAETAGFELRISDLESQLAREREEFRLRLAQKDDELAELRLTLEEQ--M 692

Query: 926 EVYADADEI---LQEEIKEYK 943
           + Y+D  +I   L  EI  Y+
Sbjct: 693 QEYSDLLDIKIRLDREIDAYR 755
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|21703798|ref|NP_663374.1| secretagogin, EF-hand
calcium binding protein [Mus musculus]
         (276 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

07198                                                                  37   0.012
14594                                                                  34   0.075
05237                                                                  34   0.082
12214                                                                  33   0.18 
01019                                                                  30   1.3  
11425                                                                  30   1.4  
03616                                                                  27   10.0 
>07198
          Length = 1675

 Score = 36.6 bits (83), Expect = 0.012,   Method: Compositional matrix adjust.
 Identities = 40/155 (25%), Positives = 66/155 (42%)
 Frame = -3

Query: 112 QIWRKYDADSSGFISAAELCNFLRDLFLHHKKNISEAELEEYTSTMMKIFDKNKDGRLDL 171
           +++   DA+  G +++ E   F          +  + ELE +    M+  DKNKDG + +
Sbjct: 470 KVFDAADANKDGSLNSKEYFAFFM------PNSFPQLELERF----MRQSDKNKDGTISM 321

Query: 172 NDLARILALQENFLLQFKMDASSTEERKRDFEKIFAHYDVSKTGALEGPEVDGFVKDMME 231
            +                M   +T + +   E+ F +YD  K G+L        +++ ME
Sbjct: 320 EEF---------------MPEGATGDTRTSSEESFKNYDKDKDGSLS-------LEEAME 207

Query: 232 LVQPSISGVDLDKFREILLRHCDVNKDGKIQKSEL 266
            + PS S    D   E L    DVN DGK+ K E+
Sbjct: 206 WINPS-SDEHADVEVEHLFTIGDVNHDGKLSKDEI 105
>14594
          Length = 1014

 Score = 33.9 bits (76), Expect = 0.075,   Method: Compositional matrix adjust.
 Identities = 39/166 (23%), Positives = 65/166 (39%)
 Frame = +3

Query: 14  AACFWQIWQRFDKEEKGYIRETELDAFFDHLLAKSGTEDTLMEENVQKVKEQLMTSHNVS 73
            A F + +  FDK+  G I  +EL       L ++ TE+ L         + ++   +  
Sbjct: 438 VAEFKEAFSLFDKDGDGTITTSELGTVM-RSLGQNPTENEL---------QDMINEVDAD 587

Query: 74  KEGRILMKELASMFLSEDENFLLFFRLETPLDNSVEFMQIWRKYDADSSGFISAAELCNF 133
             G I  +E   M            R     D   E  + +R +D D +G+ISAAEL   
Sbjct: 588 GNGTIDFEEFLHMMA----------RKMKDTDCEEELREAFRVFDKDGNGYISAAEL--- 728

Query: 134 LRDLFLHHKKNISEAELEEYTSTMMKIFDKNKDGRLDLNDLARILA 179
                 H   N+ E   +E    M+K  D + DG ++  +   ++ 
Sbjct: 729 -----RHVMTNLGEKLTDEEVDEMIKEADLDGDGMVNYEEFVTMMT 851
>05237
          Length = 472

 Score = 33.9 bits (76), Expect = 0.082,   Method: Compositional matrix adjust.
 Identities = 20/77 (25%), Positives = 38/77 (49%)
 Frame = +3

Query: 105 DNSVEFMQIWRKYDADSSGFISAAELCNFLRDLFLHHKKNISEAELEEYTSTMMKIFDKN 164
           D   E  + +R +D D +GFISA+EL         H   N+ E   +E    M++  D +
Sbjct: 18  DTDDELREAFRVFDKDGNGFISASEL--------RHVMTNLGEKLTDEEVDEMIREADID 173

Query: 165 KDGRLDLNDLARILALQ 181
            DG+++  +  +++  +
Sbjct: 174 GDGQVNYEEFVKMMTTK 224
>12214
          Length = 654

 Score = 32.7 bits (73), Expect = 0.18,   Method: Compositional matrix adjust.
 Identities = 24/89 (26%), Positives = 39/89 (43%)
 Frame = -3

Query: 157 MMKIFDKNKDGRLDLNDLARILALQENFLLQFKMDASSTEERKRDFEKIFAHYDVSKTGA 216
           M+ +FD++  G +D+N+           L Q+     ST ER          YD +++G+
Sbjct: 640 MIGMFDRDMSGTIDINEFQS--------LWQYIQQWRSTFER----------YDSNRSGS 515

Query: 217 LEGPEVDGFVKDMMELVQPSISGVDLDKF 245
           +EG E+    + M   V P      L KF
Sbjct: 514 IEGNELQAAYQQMGFNVSPRFVQTVLYKF 428
>01019
          Length = 1705

 Score = 29.6 bits (65), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 18/63 (28%), Positives = 31/63 (49%)
 Frame = +1

Query: 117 YDADSSGFISAAELCNFLRDLFLHHKKNISEAELEEYTSTMMKIFDKNKDGRLDLNDLAR 176
           +D D +GFISAAEL         H   N+ E   +E    M++  D + DG+++  +   
Sbjct: 46  FDKDGNGFISAAEL--------RHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVT 201

Query: 177 ILA 179
           ++ 
Sbjct: 202 MMT 210
>11425
          Length = 599

 Score = 29.6 bits (65), Expect = 1.4,   Method: Compositional matrix adjust.
 Identities = 16/45 (35%), Positives = 27/45 (60%)
 Frame = -2

Query: 108 VEFMQIWRKYDADSSGFISAAELCNFLRDLFLHHKKNISEAELEE 152
            +FM+ ++ +D +  GFISAAE    LR L     + +S+ E++E
Sbjct: 331 ADFMEGFKTFDREGQGFISAAE----LRHLLTGLGERLSDDEVDE 209
>03616
          Length = 2372

 Score = 26.9 bits (58), Expect = 10.0,   Method: Compositional matrix adjust.
 Identities = 16/67 (23%), Positives = 34/67 (50%)
 Frame = +2

Query: 112 QIWRKYDADSSGFISAAELCNFLRDLFLHHKKNISEAELEEYTSTMMKIFDKNKDGRLDL 171
           +++ +YD D +G+IS   + +  R L L    ++  A +++ T         +++GR+ L
Sbjct: 893 EMFLRYDRDRTGYISVENMRDLCRRLQLPVDDDVILALVQQCTM--------DQEGRISL 1048

Query: 172 NDLARIL 178
            D  R +
Sbjct: 1049EDFRRFV 1069
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|94386519|ref|XP_135146.8| PREDICTED: DnaJ (Hsp40)
homolog, subfamily C, member 13 isoform 1 [Mus musculus]
         (2436 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

14550                                                                  40   0.013
02324                                                                  38   0.052
15360                                                                  33   0.99 
08718                                                                  33   1.9  
>14550
          Length = 1395

 Score = 39.7 bits (91), Expect = 0.013,   Method: Composition-based stats.
 Identities = 18/49 (36%), Positives = 29/49 (59%), Gaps = 3/49 (6%)
 Frame = -1

Query: 1509 DESKIRKAYFRLAQKYHPDKN---PEGRDMFEKVNKAYEFLCTKSTKIV 1554
            D  +I++AY ++A++ HPDKN   PE    F+ +  AYE L  +  + V
Sbjct: 1098 DTKQIKRAYRKIAKELHPDKNRDDPEAEQRFQDLGAAYEVLSDEEKRKV 952
>02324
          Length = 2058

 Score = 37.7 bits (86), Expect = 0.052,   Method: Compositional matrix adjust.
 Identities = 24/55 (43%), Positives = 30/55 (54%), Gaps = 4/55 (7%)
 Frame = +2

Query: 1496 YEVLNLPIGQGLHDESKIRKAYFRLAQKYHPDKNP----EGRDMFEKVNKAYEFL 1546
            YEVL +       D   ++KAY +LA K+HPDKNP    E    F  V +AYE L
Sbjct: 110  YEVLGVERSA---DNDDLKKAYRKLALKFHPDKNPDSVEEATAQFRLVQQAYEIL 265
>15360
          Length = 502

 Score = 33.5 bits (75), Expect = 0.99,   Method: Compositional matrix adjust.
 Identities = 18/66 (27%), Positives = 37/66 (56%), Gaps = 3/66 (4%)
 Frame = +1

Query: 1490 MSIDDAYEVLNLPIGQGLHDESKIRKAYFRLAQKYHPDKN---PEGRDMFEKVNKAYEFL 1546
            ++ + A+ +L++P G    D+  ++  Y +LA K+HP+K+    E    F +V +AY  L
Sbjct: 43   LTREAAFNLLDIPAG---SDQESLKTKYKQLALKWHPEKHKNAAEAVKQFIQVTQAYRLL 213

Query: 1547 CTKSTK 1552
               +++
Sbjct: 214  AYNTSQ 231
>08718
          Length = 1556

 Score = 32.7 bits (73), Expect = 1.9,   Method: Compositional matrix adjust.
 Identities = 36/131 (27%), Positives = 57/131 (43%), Gaps = 20/131 (15%)
 Frame = +3

Query: 385 KSAIEHAGNYIGISLRIRKEPLEFEQYLNLRFGKYS-----TDESITSLAEFVVQKISPR 439
           K  IE    YI  S   ++E  E E  L+   G  S      DE ++ + E + Q    +
Sbjct: 141 KKRIEKLQEYIRTSTIAQQEQRESELQLSSEVGAASGRVESIDEELSGIQEQLGQAKVDK 320

Query: 440 HS-----------EPVKRVLAVTETCLVER-DPA--TYNIATLKPLGEVF-ALVCDSENP 484
           H            E +KR+       L+++ +P+   Y +A  K LG+   A+VCDSE  
Sbjct: 321 HESSRAVRKAELLENLKRLFPGVHGRLIDQCEPSHKRYQVAITKVLGKYMDAIVCDSEKT 500

Query: 485 QLFTIEFIKGQ 495
               I+++K Q
Sbjct: 501 AKDCIQYMKEQ 533
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|40254600|ref|NP_033802.2| acidic (leucine-rich)
nuclear phosphoprotein 32 family, member A [Mus musculus]
         (247 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

15929                                                                  36   0.016
17623                                                                  30   1.0  
04324                                                                  29   2.1  
36788                                                                  27   7.0  
>15929
          Length = 1074

 Score = 35.8 bits (81), Expect = 0.016,   Method: Compositional matrix adjust.
 Identities = 23/72 (31%), Positives = 33/72 (45%)
 Frame = +3

Query: 75  RISGDLEVLAEKCPNLKHLNLSGNKIKDLSTIEPLKKLENLKSLDLFNCEVTNLNAYREN 134
           RI   +E L E  PN+  + L+ N I +L  ++PL     L+ L L    V     YR  
Sbjct: 414 RIVRIVENLGEVIPNINTVVLTNNNIHELGDLDPLASFTKLEYLSLMRNPVNAKKHYRLY 593

Query: 135 VFKLLPQVMYLD 146
           V   +P +  LD
Sbjct: 594 VIFKIPSLRVLD 629
>17623
          Length = 687

 Score = 30.0 bits (66), Expect = 1.0,   Method: Compositional matrix adjust.
 Identities = 22/73 (30%), Positives = 37/73 (50%), Gaps = 5/73 (6%)
 Frame = +2

Query: 89  NLKHLNLSGNKIKDLSTIEPLKKLENLKSLDLFN-----CEVTNLNAYRENVFKLLPQVM 143
           +L+ LNLSGN I  L  +  L +L  L+S+ + +     C V+ L  Y  ++   LP   
Sbjct: 398 HLEDLNLSGNPISSLRDVTNLVRLPQLQSVSMKDPLYRPCPVSQLCNYSTHILFHLPTPP 577

Query: 144 YLDGYDRDNKEAP 156
              G+ R +++ P
Sbjct: 578 P-PGHVRRHRQTP 613
>04324
          Length = 1027

 Score = 28.9 bits (63), Expect = 2.1,   Method: Compositional matrix adjust.
 Identities = 23/53 (43%), Positives = 28/53 (52%), Gaps = 5/53 (9%)
 Frame = -1

Query: 100 IKDLSTIEPLKKLENLKSLDLFNCEVTNL--NAYRENVFKLL-PQVMY--LDG 147
           +K LS I  LKKL N  + DLF C V++    A RE  FK   P   Y  +DG
Sbjct: 661 LKLLSNIY-LKKLSNYSNTDLFKCGVSSFFQGAGRETWFKAWTPSRRYRSMDG 506
>36788
          Length = 435

 Score = 26.9 bits (58), Expect = 7.0,   Method: Compositional matrix adjust.
 Identities = 17/44 (38%), Positives = 23/44 (52%), Gaps = 1/44 (2%)
 Frame = +2

Query: 80  LEVLAEKCPNLKHLNLSGNKIKDLSTIEPLKKLE-NLKSLDLFN 122
             ++AEKC NLK L L+ N+    S I  L K    L+ LD+  
Sbjct: 101 FTIIAEKCRNLKKLFLTANRTVCDSDIMRLAKYSLQLQQLDILG 232
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|82890950|ref|XP_619958.2| PREDICTED: synaptopodin 2
isoform 1 [Mus musculus]
         (1257 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

38751                                                                  39   0.016
20073                                                                  36   0.084
03831                                                                  36   0.12 
20530                                                                  33   0.50 
04004                                                                  32   2.2  
>38751
          Length = 329

 Score = 38.5 bits (88), Expect = 0.016,   Method: Composition-based stats.
 Identities = 18/53 (33%), Positives = 28/53 (52%)
 Frame = +3

Query: 21 LQGGKEEQQPLQVAKIRSQSKASGSGLREGDEVVSINGNPCADLTYPEVIKLM 73
          ++GGKE   P+ V  I    +A   GL  GD ++ +NG     LT+ E + +M
Sbjct: 9  IKGGKEYGTPIVVYVIEEGCQAEQQGLNIGDRILDVNGTDFTHLTHAEAVTIM 167
>20073
          Length = 582

 Score = 36.2 bits (82), Expect = 0.084,   Method: Composition-based stats.
 Identities = 19/69 (27%), Positives = 40/69 (57%), Gaps = 1/69 (1%)
 Frame = +3

Query: 18 GFRLQGGKEEQQPLQVAKIRSQSKASG-SGLREGDEVVSINGNPCADLTYPEVIKLMEGI 76
          GF + GGKE+  P+ +++I     A   + L+ GD+++S+NG       + + ++L++  
Sbjct: 9  GFNVMGGKEQSSPIYISRIIPGGVADRLNCLKRGDQLLSVNGVSVEGEYHEKAVELLKLA 188

Query: 77 TDSLHLLVK 85
            S+ L+V+
Sbjct: 189QGSVRLVVR 215
>03831
          Length = 1143

 Score = 35.8 bits (81), Expect = 0.12,   Method: Compositional matrix adjust.
 Identities = 19/68 (27%), Positives = 33/68 (48%)
 Frame = +3

Query: 17  WGFRLQGGKEEQQPLQVAKIRSQSKASGSGLREGDEVVSINGNPCADLTYPEVIKLMEGI 76
           +GF L   K +     + K+   S A  +GL+ GD +V +NG    +  + +V+  ++  
Sbjct: 171 YGFNLHAEKGKAGQF-IGKVDEGSPAEAAGLKAGDRIVEVNGTNIGNENHQQVVGRIKAG 347

Query: 77  TDSLHLLV 84
            D   LLV
Sbjct: 348 GDETRLLV 371

 Score = 34.3 bits (77), Expect = 0.32,   Method: Compositional matrix adjust.
 Identities = 20/69 (28%), Positives = 34/69 (49%), Gaps = 1/69 (1%)
 Frame = +3

Query: 17  WGFRLQGGKEEQQPLQ-VAKIRSQSKASGSGLREGDEVVSINGNPCADLTYPEVIKLMEG 75
           +GF L    E+ +P Q +  +   S A   GL+EGD ++ +NG       +  VI+ ++ 
Sbjct: 618 YGFNLHA--EKDKPGQYIGSVDPNSPAETGGLKEGDRIIEVNGENIETTNHTAVIQNIKS 791

Query: 76  ITDSLHLLV 84
             D   +LV
Sbjct: 792 RGDKTSMLV 818
>20530
          Length = 431

 Score = 33.5 bits (75), Expect = 0.50,   Method: Compositional matrix adjust.
 Identities = 19/57 (33%), Positives = 35/57 (61%)
 Frame = +1

Query: 30 PLQVAKIRSQSKASGSGLREGDEVVSINGNPCADLTYPEVIKLMEGITDSLHLLVKR 86
          P+ V+++ ++ +ASG  L+EGD VV++NG  C  +    V +L++    +L L + R
Sbjct: 16 PVYVSQVTNEERASG--LQEGDIVVAVNGVSCGGIHM--VTQLVDSAFRTLTLTLWR 174
>04004
          Length = 1751

 Score = 31.6 bits (70), Expect = 2.2,   Method: Compositional matrix adjust.
 Identities = 16/34 (47%), Positives = 18/34 (52%)
 Frame = -1

Query: 1088 GRSAPPIISASPWLYQSACNYSSKPTFELEKANK 1121
             RSAPP    SP  Y +AC   S PT E+  A K
Sbjct: 395  SRSAPPACLESPRRYSAACCVQSTPTVEMSAACK 294
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|117647240|ref|NP_663502.3| MAP-kinase activating
death domain [Mus musculus]
         (1558 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

37537                                                                  39   0.017
28383                                                                  32   2.2  
>37537
          Length = 696

 Score = 38.9 bits (89), Expect = 0.017,   Method: Compositional matrix adjust.
 Identities = 28/107 (26%), Positives = 49/107 (45%), Gaps = 2/107 (1%)
 Frame = -1

Query: 276 QQALTFALPDPSRFTLVDFPLHLPLELLGVDA--CLQVLTCILLEHKVVLQSRDYNALSM 333
           Q    F  P PS    +    +L      VD    +++   +L E +++  S+  + ++ 
Sbjct: 324 QDMFNFTAPKPSCLPSIPASRNLTEYYNAVDTNNMMKIFASMLHERRIIFTSKKLSRVTA 145

Query: 334 SVMAFVAMIYPLEYMFPVIPLLPTCMASAEQLLLAPTPYIIGVPASF 380
            + A   ++YP+ +    IP+LP   A     + AP PYIIGV +S 
Sbjct: 144 CIHASECLLYPMHWQHLYIPVLP---AHLIDYVTAPMPYIIGVHSSL 13
>28383
          Length = 724

 Score = 32.0 bits (71), Expect = 2.2,   Method: Composition-based stats.
 Identities = 30/98 (30%), Positives = 45/98 (45%)
 Frame = -1

Query: 1451 VYERWWYEKLINMTYCPKTKVLCLWRRNGSETQLNKFYTKKCRELYYCVKDSMERAAARQ 1510
            ++E ++Y KLIN+ +  K  V  LW      +++  F T  C   Y C    +E+ A   
Sbjct: 577  IHEXFYY-KLINVHFYFKHXVSVLW*-----SKMFNFKTVICDGSYSCSMHVLEKIAT-- 422

Query: 1511 QSIKPGPELGGEFPVQDMKTGEGGLLQVTLEGINLKFM 1548
                P P      PV  +K  +G LLQ  +  INL F+
Sbjct: 421  ----PPPXPFN--PVLLLKNFQGKLLQQII*EINLNFL 326
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|167234372|ref|NP_663600.2| eukaryotic translation
initiation factor 4B [Mus musculus]
         (611 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

30935                                                                  37   0.018
00556                                                                  33   0.39 
12593                                                                  32   0.62 
10194                                                                  32   0.76 
32386                                                                  30   3.2  
03000                                                                  30   3.8  
19625                                                                  30   4.0  
39789                                                                  29   5.6  
11108                                                                  29   5.8  
>30935
          Length = 802

 Score = 37.4 bits (85), Expect = 0.018,   Method: Compositional matrix adjust.
 Identities = 25/58 (43%), Positives = 37/58 (63%), Gaps = 1/58 (1%)
 Frame = -1

Query: 430 SATSGRNTRRRESEKS-LENETLNKEEDCHSPTSKPPKPDQPLKVMPAPPPKENAWVK 486
           S +SG++  RR+SE S + +++   E D      +PP  D+  K+MPAPPPKENAW +
Sbjct: 601 SNSSGKSGSRRDSETSRVSDDSHGSERDG-----RPPVRDE-RKLMPAPPPKENAWSR 446
>00556
          Length = 2189

 Score = 32.7 bits (73), Expect = 0.39,   Method: Compositional matrix adjust.
 Identities = 20/53 (37%), Positives = 29/53 (54%)
 Frame = +3

Query: 64  RAPPIDRSILPTAPRAAREPNIDRSRLPKSPPYTAFLGNLPYDVTEDSIKDFF 116
           +A PI  +I PTA      P    SR  +      ++GN+P+ VTE+S+ DFF
Sbjct: 351 QAMPISATINPTA--TVTLPGSAMSRQARR----LYVGNIPFGVTEESMMDFF 491
>12593
          Length = 462

 Score = 32.3 bits (72), Expect = 0.62,   Method: Composition-based stats.
 Identities = 16/42 (38%), Positives = 25/42 (59%)
 Frame = +1

Query: 96  YTAFLGNLPYDVTEDSIKDFFRGLNISAVRLPREPSNPDRLK 137
           YTA++GNLP  + +  ++  F+ L +  VRL R+    DR K
Sbjct: 4   YTAYVGNLPDGLVQGDLELIFKDLKVKTVRLVRD-RETDRFK 126
>10194
          Length = 1278

 Score = 32.0 bits (71), Expect = 0.76,   Method: Compositional matrix adjust.
 Identities = 13/33 (39%), Positives = 20/33 (60%), Gaps = 4/33 (12%)
 Frame = -3

Query: 97  TAFLGNLPYDVTEDSIKDFFRGL----NISAVR 125
           + F+GNLP+D+ E+S++  F       NI  VR
Sbjct: 403 SVFVGNLPFDIEEESVRSHFEDCGDVENIRVVR 305
>32386
          Length = 674

 Score = 30.0 bits (66), Expect = 3.2,   Method: Compositional matrix adjust.
 Identities = 14/43 (32%), Positives = 21/43 (48%)
 Frame = +1

Query: 99  FLGNLPYDVTEDSIKDFFRGLNISAVRLPREPSNPDRLKGFGY 141
           F+G L Y+  EDS++  F         +    SN  R +GFG+
Sbjct: 310 FIGGLSYETDEDSLRSHFETWGEIVDCIVMRDSNSKRSRGFGF 438
>03000
          Length = 778

 Score = 29.6 bits (65), Expect = 3.8,   Method: Compositional matrix adjust.
 Identities = 14/44 (31%), Positives = 21/44 (47%)
 Frame = +3

Query: 99  FLGNLPYDVTEDSIKDFFRGLNISAVRLPREPSNPDRLKGFGYA 142
           F+G L Y+  EDS++  F         +    SN  R +GFG+ 
Sbjct: 96  FIGGLSYETDEDSLRSHFETWGEIVDCIVMRDSNSKRSRGFGFI 227
>19625
          Length = 703

 Score = 29.6 bits (65), Expect = 4.0,   Method: Compositional matrix adjust.
 Identities = 16/44 (36%), Positives = 22/44 (50%)
 Frame = -2

Query: 432 TSGRNTRRRESEKSLENETLNKEEDCHSPTSKPPKPDQPLKVMP 475
           T   N  +++    L +     EEDCHSPT   PKP  P  ++P
Sbjct: 144 TPSANPPKQQQNNQLVDGCSTNEEDCHSPT---PKPSYPCSLIP 22
>39789
          Length = 361

 Score = 28.9 bits (63), Expect = 5.6,   Method: Compositional matrix adjust.
 Identities = 15/44 (34%), Positives = 24/44 (54%)
 Frame = +1

Query: 99  FLGNLPYDVTEDSIKDFFRGLNISAVRLPREPSNPDRLKGFGYA 142
           F+GNL YD  + S+KD F G   + +   ++   P   +GFG+ 
Sbjct: 97  FVGNLSYDTDQYSLKDAFPGATAARIAKFQDTQKP---RGFGFV 219
>11108
          Length = 493

 Score = 28.9 bits (63), Expect = 5.8,   Method: Composition-based stats.
 Identities = 13/43 (30%), Positives = 22/43 (51%)
 Frame = -1

Query: 99  FLGNLPYDVTEDSIKDFFRGLNISAVRLPREPSNPDRLKGFGY 141
           FLG +P+D++E S+   F+      V  P +     + KG+ Y
Sbjct: 283 FLGGIPWDISEQSLIQIFKPFGSIKVEWPGKEQQAAQPKGYVY 155
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|21312944|ref|NP_080468.1| calcium binding and coiled
coil domain 1 [Mus musculus]
         (691 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

25491                                                                  37   0.019
35150                                                                  30   3.7  
04618                                                                  28   10.0 
>25491
          Length = 441

 Score = 37.4 bits (85), Expect = 0.019,   Method: Compositional matrix adjust.
 Identities = 36/121 (29%), Positives = 60/121 (49%), Gaps = 7/121 (5%)
 Frame = -2

Query: 177 LRSRVQELEAALATARQEHSELTEQYKGLSRSHGELSEERDILSQQQGDHVARILELEDD 236
           L   V +L A+L +A+ E   LTEQ   L+ S   L  ERD L ++       I  L+DB
Sbjct: 419 LTKHVTDLTASLQSAQSEKDSLTEQVTNLTASSAALQSERDKLCEE-------IASLKDB 261

Query: 237 IQTMSDKVLMKEVELDRVR-------DTVKALTREQEKLLRQLKEFQADKEQSEAELQTV 289
           + T +  +  +  +L+ VR       D V+AL+ E++    +L   +AD E++  +L T 
Sbjct: 260 LXTQTRNLEAQTDQLEAVRGDLKSEQDLVEALSSEKQTYWTKLLNVKADLEETAQDLVTA 81

Query: 290 R 290
           +
Sbjct: 80  K 78
>35150
          Length = 410

 Score = 30.0 bits (66), Expect = 3.7,   Method: Compositional matrix adjust.
 Identities = 22/78 (28%), Positives = 36/78 (46%)
 Frame = +2

Query: 181 VQELEAALATARQEHSELTEQYKGLSRSHGELSEERDILSQQQGDHVARILELEDDIQTM 240
           V ELE +LA  +   ++  +  KGL+R+                      L+LEDDIQ  
Sbjct: 209 VGELECSLAQLQSRLADTQDSLKGLTRNQ---------------------LDLEDDIQVK 325

Query: 241 SDKVLMKEVELDRVRDTV 258
           S+ + + EVE   +R ++
Sbjct: 326 SNTLFIDEVECMGMRKSI 379
>04618
          Length = 1663

 Score = 28.5 bits (62), Expect = 10.0,   Method: Compositional matrix adjust.
 Identities = 30/95 (31%), Positives = 43/95 (45%)
 Frame = -3

Query: 170  LEDQVTELRSRVQELEAALATARQEHSELTEQYKGLSRSHGELSEERDILSQQQGDHVAR 229
            L+DQV +    V+ +E  LA    E S+L EQY+ LS    +          Q   H   
Sbjct: 1394 LKDQVQKYILEVRRVEDMLANKEAERSDLLEQYRKLSLEAEQF---------QTTSH--- 1251

Query: 230  ILELEDDIQTMSDKVLMKEVELDRVRDTVKALTRE 264
              +LE +   M  +++ KE EL R  D +  L RE
Sbjct: 1250 --QLESEGSNMRLEIMTKESELRRAHDKLDNLERE 1152
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|40254521|ref|NP_079559.2| preimplantation protein 3
[Mus musculus]
         (225 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

38115                                                                  35   0.022
14212                                                                  32   0.17 
23223                                                                  30   0.60 
06192                                                                  29   1.3  
24653                                                                  28   3.2  
00763                                                                  27   8.9  
>38115
          Length = 648

 Score = 35.0 bits (79), Expect = 0.022,   Method: Compositional matrix adjust.
 Identities = 23/100 (23%), Positives = 43/100 (43%), Gaps = 3/100 (3%)
 Frame = +3

Query: 52  SNIDKILEPPEGQDEGVWKYEHLRQFCLELNGLAVKLQSECHPDTCTQMTATEQWIFLCA 111
            N+   +  P+G+D   W   +   F  ++N L   +   C  D+C  M+A  ++ +  A
Sbjct: 303 GNLRNAVALPDGEDLNEWVAVNTVDFFNQINMLYGTITEFCTEDSCGIMSAGPKYEYHWA 482

Query: 112 ---AHKTPKECPAIDYTRHTLDGAACLLNSNKYFPSRVSI 148
                K P +C A  Y  + +      L+    FPS++ +
Sbjct: 483 DGLTVKKPIKCSAPKYIDYLMTWVQDQLDDETLFPSKIGV 602
>14212
          Length = 505

 Score = 32.3 bits (72), Expect = 0.17,   Method: Compositional matrix adjust.
 Identities = 15/29 (51%), Positives = 18/29 (62%)
 Frame = +1

Query: 78  CLELNGLAVKLQSECHPDTCTQMTATEQW 106
           C+ +N  AVK   EC  DTCTQ T T+ W
Sbjct: 10  CVHMNINAVKYFIECGVDTCTQYTYTQLW 96
>23223
          Length = 2990

 Score = 30.4 bits (67), Expect = 0.60,   Method: Compositional matrix adjust.
 Identities = 16/53 (30%), Positives = 29/53 (54%)
 Frame = +1

Query: 139 NKYFPSRVSIKESSVAKLGSVCRRIYRIFSHAYFHHRQIFDEYENETFLCHRF 191
           +++ P+R+SI+    ++L        +IF+H Y H R I+  + + TF   RF
Sbjct: 526 SQFLPTRLSIRSHVTSQL--------QIFTHTYTHARSIYLFFTSTTFYILRF 660
>06192
          Length = 1932

 Score = 29.3 bits (64), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 15/41 (36%), Positives = 20/41 (48%)
 Frame = +1

Query: 71   YEHLRQFCLELNGLAVKLQSECHPDTCTQMTATEQWIFLCA 111
            Y+  R+F LE    A+  +    PDTC   +  E W FL A
Sbjct: 1543 YKDTRRFPLEAPSCALLFRPCRLPDTCPPFSLREAWRFLIA 1665
>24653
          Length = 1240

 Score = 28.1 bits (61), Expect = 3.2,   Method: Compositional matrix adjust.
 Identities = 12/27 (44%), Positives = 15/27 (55%)
 Frame = -1

Query: 183 NETFLCHRFTKFVMKYNLMSKDNLIVP 209
           N T  C R  KF  +YN +S+  LI P
Sbjct: 127 NSTIQCSREIKFTAQYNTLSEGKLIRP 47
>00763
          Length = 2291

 Score = 26.6 bits (57), Expect = 8.9,   Method: Compositional matrix adjust.
 Identities = 10/25 (40%), Positives = 13/25 (52%)
 Frame = +2

Query: 97   CTQMTATEQWIFLCAAHKTPKECPA 121
            CT+     QW  LC+A  +P  CP 
Sbjct: 2120 CTRWRWVRQWCVLCSAPWSPAGCPC 2194
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|11230778|ref|NP_068683.1| tropomodulin 1 [Mus
musculus]
         (359 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

31609                                                                  36   0.024
04857                                                                  30   1.5  
>31609
          Length = 841

 Score = 36.2 bits (82), Expect = 0.024,   Method: Compositional matrix adjust.
 Identities = 20/67 (29%), Positives = 33/67 (49%)
 Frame = +1

Query: 221 KENSYVKKFSIVGTRSNDPVAFALAEMLKVNKVLKTLNVESNFISGAGILRLVEALPHNT 280
           + N  +K+  +      DP   A  EML  N  L  L++ SN +  +G++ L   + HN 
Sbjct: 355 QGNLCLKRLLLANNGIGDPGCMAAGEMLANNSTLLELDIASNRVLDSGLVALANNIKHNE 534

Query: 281 SLVELKI 287
           +L  LK+
Sbjct: 535 TLQTLKL 555
>04857
          Length = 1077

 Score = 30.0 bits (66), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 36/140 (25%), Positives = 64/140 (45%), Gaps = 5/140 (3%)
 Frame = +3

Query: 189 RIKNNDPELEEVNLNNIRNIPIPTLKAYAEA----LKENSYVKKFSIVGTRSNDPVAFAL 244
           RI N D + +      IR + +       EA    +K  S +   S+ G  + D +A  +
Sbjct: 492 RIDNQDMK-DIAEFTEIRTLKLDNCYRLNEAGLQEVKALSRLTWLSVAGCATTDLLAHHI 668

Query: 245 AEMLKVNKVLKTLNV-ESNFISGAGILRLVEALPHNTSLVELKIDNQSQPLGNKVEMEIV 303
           +  L     L+ L++  S F++ AG+  +V+ALP  TSLV   +D+        + +   
Sbjct: 669 SRNLPA---LQHLDLSRSRFLTEAGLPGMVQALPKLTSLV---LDDCVN-----ITLRAF 815

Query: 304 NMLEKNTTLLKFGYHFTQQG 323
           ++L K+ +L K    FT+  
Sbjct: 816 SVLCKSPSLKKLSLVFTKDA 875
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|120300971|ref|NP_444434.2| Rab6-interacting protein 2
isoform 1 [Mus musculus]
         (1120 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

28486                                                                  38   0.025
01964                                                                  33   0.62 
22803                                                                  31   2.3  
04618                                                                  30   5.3  
17811                                                                  30   8.0  
>28486
          Length = 771

 Score = 37.7 bits (86), Expect = 0.025,   Method: Compositional matrix adjust.
 Identities = 58/204 (28%), Positives = 95/204 (46%), Gaps = 23/204 (11%)
 Frame = -2

Query: 425 QMEVYRSHSKFMKNKVEQLKEELSSKDAQGEELKKRAAG--------LQSEIGQVKQEL- 475
           Q+ + RS +K+   K +Q     + + A  E+     +G        LQ  +GQ K EL 
Sbjct: 590 QLPILRSWTKW*PRKTKQKASS*TDQPAD*EQCHGTESGTTGKGNKELQDHMGQKKTELD 411

Query: 476 ---------SRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDA 526
                    S  D EL     +LE     F+++K  IE  K+ L     R  +L+ E D+
Sbjct: 410 ELMRAMKAESSVDVELKERIKELE-----FANNK--IEDYKKDLADINHRHEVLEKEKDS 252

Query: 527 LR--LRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQ 584
           ++  LRL+E E       K ++   EEK TQ GE+          +R+V+  ++ I+ L+
Sbjct: 251 VKNALRLKESEC------KGLKVSVEEKDTQIGEL----------KRQVDTAKRNIKRLE 120

Query: 585 EQLRDK---EKQMSSLKERVKSLQ 605
           + L D    EK + ++K RV+SL+
Sbjct: 119 DDLEDTKQVEKDVVNMKARVRSLK 48
>01964
          Length = 2512

 Score = 33.1 bits (74), Expect = 0.62,   Method: Compositional matrix adjust.
 Identities = 35/142 (24%), Positives = 71/142 (50%), Gaps = 18/142 (12%)
 Frame = -3

Query: 481  ELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNK 540
            E+ ALQ K +  +   +  +  I  LKE +  K+Q+A+  + +VD LR + +   T   +
Sbjct: 2063 EIAALQDKCQKYSTSVAKHELTITKLKEDVFEKQQQASTWEAKVDQLRAQYDTLRTHEQR 1884

Query: 541  KTKQIQDMAEEKGTQAGEIHDLK------------------DMLDVKERKVNVLQKKIEN 582
               +++ +  E+ +QA    +L+                  + +D  E++V +L+++++N
Sbjct: 1883 LVAELESLRRERQSQAMLTANLQAIQNNLERAEFESKTRYTNQIDSMEKEVALLRRRLQN 1704

Query: 583  LQEQLRDKEKQMSSLKERVKSL 604
             +E   +K   +SSL+  VKSL
Sbjct: 1703 AEE---EKSTTISSLETTVKSL 1647
>22803
          Length = 335

 Score = 31.2 bits (69), Expect = 2.3,   Method: Compositional matrix adjust.
 Identities = 23/78 (29%), Positives = 43/78 (55%)
 Frame = +3

Query: 438 NKVEQLKEELSSKDAQGEELKKRAAGLQSEIGQVKQELSRKDTELLALQTKLETLTNQFS 497
           N+ EQL+ E+ +   +   L+KR   +++E+     ++SRK+        +L +  N+  
Sbjct: 102 NEAEQLRTEVGALKEECSNLRKRIQAIEAEM-----KMSRKEN------LQLSSEYNKLQ 248

Query: 498 DSKQHIEVLKESLTAKEQ 515
           +S +H+E LKE L + EQ
Sbjct: 249 ESYKHLEALKEKLASSEQ 302
>04618
          Length = 1663

 Score = 30.0 bits (66), Expect = 5.3,   Method: Compositional matrix adjust.
 Identities = 32/138 (23%), Positives = 69/138 (50%), Gaps = 5/138 (3%)
 Frame = -3

Query: 334 RRLAEAEMHVHHLESLLEQKEKENNMLREEMHRRFENAPDSAKTKALQTVIEMKDSK--- 390
           RRLA  ++    L SL+E   +E+  L++++      + + +  K L+ +++    K   
Sbjct: 968 RRLAALQLEKEQLHSLVEDLRQESECLQDQV------SQERSTVKNLEALLQNGREKEFQ 807

Query: 391 --ISSMERGLRDLEEEIQMLKSNGALSSXXXXXXMKQMEVYRSHSKFMKNKVEQLKEELS 448
             +SS ER       EIQMLK   +L+        +++  +R+ +  ++  +E+L+ +L+
Sbjct: 806 NQLSSQERNT-----EIQMLKDRLSLNESKLQSQAREVASFRTRNVELEGDIERLRRQLT 642

Query: 449 SKDAQGEELKKRAAGLQS 466
           ++D +     +  AG+ S
Sbjct: 641 NEDLKESVRCRSYAGMAS 588
>17811
          Length = 492

 Score = 29.6 bits (65), Expect = 8.0,   Method: Composition-based stats.
 Identities = 13/30 (43%), Positives = 20/30 (66%)
 Frame = -3

Query: 692 KDSRLKTLEIALEQKKEECLKMESQLKKAH 721
           KDSR  TLE+  E ++ +C + E++ K AH
Sbjct: 217 KDSRWLTLEVCREYQRNKCTRTENECKFAH 128
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|154240688|ref|NP_700440.2| WD repeat domain 19 [Mus
musculus]
         (1341 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

17595                                                                  38   0.027
15337                                                                  36   0.13 
16708                                                                  30   5.4  
24000                                                                  30   5.6  
35192                                                                  30   5.8  
31474                                                                  30   8.1  
31773                                                                  30   9.4  
>17595
          Length = 483

 Score = 38.1 bits (87), Expect = 0.027,   Method: Compositional matrix adjust.
 Identities = 23/68 (33%), Positives = 34/68 (50%), Gaps = 2/68 (2%)
 Frame = -2

Query: 742 ASNCPVAALEMRRDLQHWDSALQLAKRLAP--DQIPFISKEYAIQLEFTGDYVNALAHYE 799
           ++ C ++ LE+RR    WD A    KR       +P +   Y I    TG Y  A+A YE
Sbjct: 395 STRCFLSQLELRR--MRWDKAEIYIKRALTYHPHLPDLYNFYGIVFHKTGQYEQAVASYE 222

Query: 800 KGITGDNK 807
           + ++ DNK
Sbjct: 221 RAVSLDNK 198
>15337
          Length = 860

 Score = 35.8 bits (81), Expect = 0.13,   Method: Compositional matrix adjust.
 Identities = 18/66 (27%), Positives = 34/66 (51%), Gaps = 1/66 (1%)
 Frame = -1

Query: 100 MSFLLWSKIGSFLAVGTIKGNLLIYNHQTSRKIPVLGKHTKKITCGCWNSEN-LLALGGE 158
           +S   +S    +LAV    G+L ++N+ +   I  +  +   + C CW+ +   +  GGE
Sbjct: 320 ISEFAFSPCSRYLAVVGQDGHLRVFNYNSMELIGTMKSYFGGLLCVCWSPDGKYIVTGGE 141

Query: 159 DKMITV 164
           D ++TV
Sbjct: 140 DDLVTV 123
>16708
          Length = 1397

 Score = 30.4 bits (67), Expect = 5.4,   Method: Compositional matrix adjust.
 Identities = 21/74 (28%), Positives = 38/74 (51%)
 Frame = -1

Query: 315 LDDENKGLGTLSWTDDGQLLALSTQRGSLHVFLTKLPILGDACHTRIAYLTSLLEVTVAN 374
             +E  G+GT  +   GQ+L   T    LHV++++ P L D C T  + L+ + +  +  
Sbjct: 842 FSEEGDGIGT-DYFRLGQMLWTLTGAVLLHVWVSRPPKLPDWCRTPESELSGMSDF-IEK 669

Query: 375 LIEGEPPITVSVDV 388
           L  G+P + + V +
Sbjct: 668 LCHGDPNMRLGVTL 627
>24000
          Length = 1007

 Score = 30.4 bits (67), Expect = 5.6,   Method: Composition-based stats.
 Identities = 11/34 (32%), Positives = 21/34 (61%)
 Frame = +2

Query: 102 FLLWSKIGSFLAVGTIKGNLLIYNHQTSRKIPVL 135
           +LLW KIG +L+   + G  L++ + + + IP +
Sbjct: 686 YLLWKKIGQYLSAVRLMGQCLLWKNTSCQLIPTV 787
>35192
          Length = 328

 Score = 30.0 bits (66), Expect = 5.8,   Method: Compositional matrix adjust.
 Identities = 19/86 (22%), Positives = 38/86 (44%), Gaps = 5/86 (5%)
 Frame = +3

Query: 840 RVLKRDCGAILENMKQFSEAAQLYEKGQYYDRAASVYIRCKNWAKVGELLPHV-----SS 894
           + L ++ G  L    +  EA  ++ +GQ++  A   ++   NW +   +  H+     ++
Sbjct: 57  KTLSKEYGQYLREKNRHDEAGIMFIRGQHWQLAQEAFVAALNWRQALCMAAHMKTDDNTT 236

Query: 895 PKIHLQYAKAKEADGRYKEAVVAYEN 920
             +    A   +A  R+ EA V YE 
Sbjct: 237 ADLARSLADRLKASMRHGEAAVVYEQ 314
>31474
          Length = 403

 Score = 29.6 bits (65), Expect = 8.1,   Method: Composition-based stats.
 Identities = 16/44 (36%), Positives = 23/44 (52%), Gaps = 1/44 (2%)
 Frame = -3

Query: 128 TSRKIPVLGKHTKKITCGCWN-SENLLALGGEDKMITVSNQEGD 170
           T  ++  L  H +   C  WN +  LLA  G DK+I +  +EGD
Sbjct: 338 TLEEVCCLSAHDEHAWCVAWNPTGTLLASCGSDKIIKIWGKEGD 207
>31773
          Length = 951

 Score = 29.6 bits (65), Expect = 9.4,   Method: Composition-based stats.
 Identities = 17/49 (34%), Positives = 23/49 (46%)
 Frame = -2

Query: 539 FVYCPVNDATYEIPDFSPTIKGVLWENWPMDKGVFIAYDDDKVYTYAFH 587
           F+YC      Y +  F P   GVL   W   + V +A+  DKV  Y F+
Sbjct: 443 FLYCVEYGKYYCVHKF-PMAAGVLSFRWVTSE*VILAHQKDKVRAYKFY 300
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|40254129|ref|NP_258435.2| armadillo repeat gene
deleted in velo-cardio-facial syndrome [Mus musculus]
         (962 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

15086                                                                  37   0.027
14657                                                                  37   0.031
17927                                                                  34   0.25 
29389                                                                  32   1.0  
21785                                                                  32   1.1  
28261                                                                  31   2.0  
07628                                                                  31   3.0  
12505                                                                  30   5.9  
30599                                                                  29   9.3  
>15086
          Length = 548

 Score = 37.4 bits (85), Expect = 0.027,   Method: Composition-based stats.
 Identities = 42/134 (31%), Positives = 64/134 (47%), Gaps = 4/134 (2%)
 Frame = +1

Query: 362 LPEVLAMLRHPVDPVKANAAAYLQHLCFENEGIKRRVRQLRGL--PLLVALLDHPRAEVR 419
           +PE++ +L    D V    AA + H   + E  +  +     +   L+ AL      E  
Sbjct: 4   IPELIKLLSDE-DQVVVCQAAMMVHQLSKKEASRHAIMNSPQMIAALIRALATTDDMETT 180

Query: 420 RRACGALRNLSYGRDTDNKAAIRDCGGVPALVRLLRAARDNEVRELVTGTLWNLSSY-EP 478
           R A G L NLS+ R      AI   GG+PALV+LL +  ++ +   +T TL NL  + E 
Sbjct: 181 RCAAGTLHNLSHHRQ--GLLAIFKSGGIPALVKLLSSPVESVLFYAIT-TLHNLLLHQEG 351

Query: 479 LKMVI-IDHGLQTL 491
            KM + +  GLQ +
Sbjct: 352 SKMAVRMAGGLQKM 393

 Score = 35.8 bits (81), Expect = 0.074,   Method: Composition-based stats.
 Identities = 26/98 (26%), Positives = 43/98 (43%)
 Frame = +1

Query: 649 RTEAAKGFELLYQPEVVRLYLSLLTESRNFNTLEAAAGALQNLSAGNWTWATYIRATVRK 708
           + EA++   ++  P+++   +  L  + +  T   AAG L NLS             + K
Sbjct: 85  KKEASR-HAIMNSPQMIAALIRALATTDDMETTRCAAGTLHNLSHHRQGL-----LAIFK 246

Query: 709 ERGLPVLVELLQSETDKVVRAVAIALRNLSLDQRNKDL 746
             G+P LV+LL S  + V+      L NL L Q    +
Sbjct: 247 SGGIPALVKLLSSPVESVLFYAITTLHNLLLHQEGSKM 360

 Score = 33.5 bits (75), Expect = 0.46,   Method: Composition-based stats.
 Identities = 19/50 (38%), Positives = 26/50 (52%)
 Frame = +1

Query: 362 LPEVLAMLRHPVDPVKANAAAYLQHLCFENEGIKRRVRQLRGLPLLVALL 411
           +P ++ +L  PV+ V   A   L +L    EG K  VR   GL  +VALL
Sbjct: 256 IPALVKLLSSPVESVLFYAITTLHNLLLHQEGSKMAVRMAGGLQKMVALL 405
>14657
          Length = 918

 Score = 37.4 bits (85), Expect = 0.031,   Method: Composition-based stats.
 Identities = 49/179 (27%), Positives = 81/179 (45%), Gaps = 5/179 (2%)
 Frame = -3

Query: 318 PPFPAATAPLAQPERGSLGSLDRVVRRSPSVD-STRKEPRWRDPELPEVLAMLRHPVDPV 376
           P  P A   L++P +    ++  ++      D +TR         +PE++ +L    D V
Sbjct: 874 PDEPTAVQRLSEPSQMLKHAVVNLINYQDDADLATRA--------IPELIKLLXDE-DXV 722

Query: 377 KANAAAYLQHLCFENEGIKRRVRQLRGL--PLLVALLDHPRAEVRRRACGALRNLSYGRD 434
               AA + H   + E  +  +     +   L+ A+ +    E  R A G L NLS+ R 
Sbjct: 721 VVYQAAMMVHQLSKKEASRHAIMNSPQMIAALIRAMANTEDIETTRCAAGTLHNLSHHRQ 542

Query: 435 TDNKAAIRDCGGVPALVRLLRAARDNEVRELVTGTLWNLSSY-EPLKMVI-IDHGLQTL 491
                AI   GG+PALV+LL +  ++ +   +T TL NL  + E  KM + +  GLQ +
Sbjct: 541 --GLLAIFKSGGIPALVKLLSSPMESVLFYAIT-TLHNLLLHQEGSKMAVRLAGGLQKM 374

 Score = 34.7 bits (78), Expect = 0.17,   Method: Composition-based stats.
 Identities = 25/98 (25%), Positives = 43/98 (43%)
 Frame = -3

Query: 649 RTEAAKGFELLYQPEVVRLYLSLLTESRNFNTLEAAAGALQNLSAGNWTWATYIRATVRK 708
           + EA++   ++  P+++   +  +  + +  T   AAG L NLS             + K
Sbjct: 682 KKEASR-HAIMNSPQMIAALIRAMANTEDIETTRCAAGTLHNLSHHRQGL-----LAIFK 521

Query: 709 ERGLPVLVELLQSETDKVVRAVAIALRNLSLDQRNKDL 746
             G+P LV+LL S  + V+      L NL L Q    +
Sbjct: 520 SGGIPALVKLLSSPMESVLFYAITTLHNLLLHQEGSKM 407
>17927
          Length = 479

 Score = 34.3 bits (77), Expect = 0.25,   Method: Composition-based stats.
 Identities = 19/62 (30%), Positives = 37/62 (59%)
 Frame = +1

Query: 698 WATYIRATVRKERGLPVLVELLQSETDKVVRAVAIALRNLSLDQRNKDLIGSYAMTELVR 757
           +++  R T+ + +G+P L  LLQS+ + +V   A+ L + +   + KD+  S A T++V+
Sbjct: 67  FSSKARTTLVENQGVPALTHLLQSKDEGIVGNAALCLSHCT---QVKDVCASLADTDIVK 237

Query: 758 NV 759
            V
Sbjct: 238 QV 243
>29389
          Length = 1070

 Score = 32.3 bits (72), Expect = 1.0,   Method: Compositional matrix adjust.
 Identities = 26/108 (24%), Positives = 49/108 (45%)
 Frame = +2

Query: 368 MLRHPVDPVKANAAAYLQHLCFENEGIKRRVRQLRGLPLLVALLDHPRAEVRRRACGALR 427
           +LRHP   ++  AA  L ++   N    + V     +PLL+ L+     + ++ A  A+ 
Sbjct: 74  LLRHPKASLQKEAAWTLSNITAGNRDQIQAVIDAGLVPLLIELMHRGDFKSQKEAVWAIT 253

Query: 428 NLSYGRDTDNKAAIRDCGGVPALVRLLRAARDNEVRELVTGTLWNLSS 475
           NL+ G          +   +P L  LL  A+D ++  ++   + N+ S
Sbjct: 254 NLTSGGSIPQVGHCMEHNCLPPLCSLL-GAKDTKIILVILDAISNVCS 394
>21785
          Length = 958

 Score = 32.0 bits (71), Expect = 1.1,   Method: Composition-based stats.
 Identities = 41/157 (26%), Positives = 68/157 (43%)
 Frame = -1

Query: 679 NTLEAAAGALQNLSAGNWTWATYIRATVRKERGLPVLVELLQSETDKVVRAVAIALRNLS 738
           N++EA A  + +  A         R +VR+  G P ++ELL+SE      AV   L  L+
Sbjct: 436 NSIEALAQMVMDYQA---------RGSVREYDGFPPILELLKSEY-----AVIQKLALLT 299

Query: 739 LDQRNKDLIGSYAMTELVRNVRNAQAPAHPSAHLEEDTVVAVLNTIHEIVSDSLDNARSL 798
           LD+  +D+     + EL    R     A P  +   D  V V+  I  ++ D +D+   +
Sbjct: 298 LDRLMQDVENRSTLRELEGISRLLDFLAKPDWY---DLHVMVIMVITSMLED-IDSLELM 131

Query: 799 LQARGVPALVALVASSQSVREAKAASHVLQTVWSYKE 835
            +  G+   VAL+       E        + V S++E
Sbjct: 130 KENGGLKKFVALITDQPPPEEESKKGDKKKWVPSWQE 20
>28261
          Length = 552

 Score = 31.2 bits (69), Expect = 2.0,   Method: Compositional matrix adjust.
 Identities = 35/116 (30%), Positives = 53/116 (45%)
 Frame = -3

Query: 365 VLAMLRHPVDPVKANAAAYLQHLCFENEGIKRRVRQLRGLPLLVALLDHPRAEVRRRACG 424
           ++ +L H    V+A AA  +  +C E    +  +R+  GLP LV LL     EV+     
Sbjct: 481 LITLLSHESQDVQAAAAQAIAVMC-ETLSCRDSIREWGGLPPLVHLLSTENGEVKEAVTL 305

Query: 425 ALRNLSYGRDTDNKAAIRDCGGVPALVRLLRAARDNEVRELVTGTLWNLSSYEPLK 480
           AL NL+   +  N     +  G+  +V  L   RD EV       L N++  EPL+
Sbjct: 304 ALANLTSS-NIPNCLEXVNLNGLDEVVSALXDERD-EVVANAACILTNMAQDEPLR 143
>07628
          Length = 1090

 Score = 30.8 bits (68), Expect = 3.0,   Method: Compositional matrix adjust.
 Identities = 20/76 (26%), Positives = 34/76 (44%), Gaps = 6/76 (7%)
 Frame = +3

Query: 540 RRLRECEGLVDALLHALQSAVGRKDTDNKSVENCVCIMRNLSYHVHKEVPGADRYQEAEP 599
           ++ +E +      L ++ SAV   D+    +  CVC    + +H H++     R Q  E 
Sbjct: 15  KKKKENQSYFQRFLSSVTSAV---DSSETGLLKCVCCSSTVEHHNHQQGDLNQRLQRLED 185

Query: 600 G------IPGSTTSQR 609
           G      IP +T +QR
Sbjct: 186 GDKAREAIPAATNTQR 233
>12505
          Length = 836

 Score = 29.6 bits (65), Expect = 5.9,   Method: Composition-based stats.
 Identities = 17/35 (48%), Positives = 21/35 (60%)
 Frame = -1

Query: 422 ACGALRNLSYGRDTDNKAAIRDCGGVPALVRLLRA 456
           A G L NLS+ R      AI   GG+PALV+LL +
Sbjct: 836 AAGTLHNLSHHRQ--GLLAIFRSGGIPALVKLLSS 738
>30599
          Length = 730

 Score = 28.9 bits (63), Expect = 9.3,   Method: Compositional matrix adjust.
 Identities = 12/24 (50%), Positives = 17/24 (70%)
 Frame = +3

Query: 228 CFTLPGRREAFPMGSESGPPSGRS 251
           C TLPGRR+  P+ +  GPP+ R+
Sbjct: 147 CQTLPGRRQRRPLAASPGPPTRRN 218
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|13994221|ref|NP_085100.1| snRNP core protein SMX5
isoform 1 [Mus musculus]
         (131 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

15058                                                                  33   0.032
06054                                                                  30   0.32 
19205                                                                  27   2.0  
08481                                                                  27   3.4  
36173                                                                  26   4.7  
18245                                                                  25   8.7  
>15058
          Length = 835

 Score = 33.1 bits (74), Expect = 0.032,   Method: Compositional matrix adjust.
 Identities = 23/69 (33%), Positives = 35/69 (50%), Gaps = 3/69 (4%)
 Frame = +1

Query: 42  FFKSLVGKDVVVELKNDLSICGTLHSVDQYLNIKLTDISVTDPEKYPHMLSVKN---CFI 98
           F   L GK V+V+LK  +   G L SVD Y+N++L      + E+Y   +   N     I
Sbjct: 424 FLNGLTGKPVMVKLKWGMEYKGYLVSVDGYMNLQL-----ANTEEYVDGMLAGNLGEVLI 588

Query: 99  RGSVVRYVQ 107
           R + V Y++
Sbjct: 589 RCNNVMYIR 615
>06054
          Length = 928

 Score = 30.0 bits (66), Expect = 0.32,   Method: Compositional matrix adjust.
 Identities = 13/34 (38%), Positives = 21/34 (61%)
 Frame = -1

Query: 47  VGKDVVVELKNDLSICGTLHSVDQYLNIKLTDIS 80
           +G  + + +KND  I GTL   D Y+N+ L D++
Sbjct: 844 IGSKLHIIMKNDKEIVGTLLGFDDYVNMVLEDVT 743
>19205
          Length = 638

 Score = 27.3 bits (59), Expect = 2.0,   Method: Compositional matrix adjust.
 Identities = 9/30 (30%), Positives = 19/30 (63%)
 Frame = +1

Query: 58 DLSICGTLHSVDQYLNIKLTDISVTDPEKY 87
          DLSI    H   +YLN+ + +I++ + +++
Sbjct: 16 DLSIMSIFHLYKKYLNVSIVNININNDKRF 105
>08481
          Length = 417

 Score = 26.6 bits (57), Expect = 3.4,   Method: Compositional matrix adjust.
 Identities = 15/49 (30%), Positives = 23/49 (46%)
 Frame = +3

Query: 41  SFFKSLVGKDVVVELKNDLSICGTLHSVDQYLNIKLTDISVTDPEKYPH 89
           S FKS+ G    +  +ND   C     +  Y+NI  +  + TD  K+ H
Sbjct: 249 SLFKSISGLKATLISRNDDGSCIICTCIH*YINIHTSVQTKTDTNKHTH 395
>36173
          Length = 947

 Score = 26.2 bits (56), Expect = 4.7,   Method: Compositional matrix adjust.
 Identities = 14/48 (29%), Positives = 22/48 (45%)
 Frame = +1

Query: 60  SICGTLHSVDQYLNIKLTDISVTDPEKYPHMLSVKNCFIRGSVVRYVQ 107
           S CG   +  Q+LN  L+D+  TD    P       C +   V+ +V+
Sbjct: 463 SECGQSVTFSQFLNFTLSDLHRTDTHVRPVTQECSPCELNYDVIGHVE 606
>18245
          Length = 465

 Score = 25.0 bits (53), Expect = 8.7,   Method: Compositional matrix adjust.
 Identities = 12/41 (29%), Positives = 22/41 (53%)
 Frame = +3

Query: 53 VELKNDLSICGTLHSVDQYLNIKLTDISVTDPEKYPHMLSV 93
          ++L  +  +CG LHS        L+ +++TD    PH L++
Sbjct: 27 LDLNTNSVVCGALHSPQ-----GLSQVALTDGFNIPHCLNI 134
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|51762709|ref|XP_133979.5| PREDICTED: protein tyrosine
phosphatase, receptor type, f polypeptide (PTPRF), interacting
protein, alpha 1 isoform 1 [Mus musculus]
         (1201 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

06047                                                                  37   0.032
05388                                                                  37   0.042
12404                                                                  35   0.13 
31117                                                                  30   6.1  
12383                                                                  29   9.0  
>06047
          Length = 445

 Score = 37.4 bits (85), Expect = 0.032,   Method: Composition-based stats.
 Identities = 18/52 (34%), Positives = 30/52 (57%), Gaps = 1/52 (1%)
 Frame = -2

Query: 1036 KREESQNETRDVLVWSNDRVIRWILSIGLKEYANNLIESGVHGA-LLALDET 1086
            KR + Q +   V+ WS + V  W++SI L++Y ++ +E  + G  L  LD T
Sbjct: 294  KRGQDQGQPSGVMEWSWESVCDWLISIDLEKYTDSFMEKSITGTQLFMLDST 139
>05388
          Length = 879

 Score = 37.0 bits (84), Expect = 0.042,   Method: Composition-based stats.
 Identities = 18/52 (34%), Positives = 30/52 (57%), Gaps = 1/52 (1%)
 Frame = +2

Query: 1036 KREESQNETRDVLVWSNDRVIRWILSIGLKEYANNLIESGVHGA-LLALDET 1086
            KR + Q +   V+ WS + V  W++SI L++Y ++ +E  + G  L  LD T
Sbjct: 638  KRGQDQGQPSGVMEWSWESVCDWLISIDLEKYTDSFMEKSITGTQLFMLDST 793
>12404
          Length = 1116

 Score = 35.4 bits (80), Expect = 0.13,   Method: Composition-based stats.
 Identities = 18/57 (31%), Positives = 30/57 (52%), Gaps = 1/57 (1%)
 Frame = -1

Query: 969  EWLPSLGLPQ-YRSYFMECLVDARMLDHLTKKDLRGQLKMVDSFHRNSFQCGIMCLR 1024
            +WL +LG  + Y  + +   VD   L  +   DL   L++ DS+HR++F   +  LR
Sbjct: 954  QWLNTLGWARNYSQFAVNQTVDGLALLSMETSDLMNALQVTDSYHRSAFHLAVDFLR 784
>31117
          Length = 856

 Score = 30.0 bits (66), Expect = 6.1,   Method: Composition-based stats.
 Identities = 11/25 (44%), Positives = 15/25 (60%)
 Frame = +3

Query: 969 EWLPSLGLPQYRSYFMECLVDARML 993
           EW+  LG P Y+S F   ++D R L
Sbjct: 111 EWIEELGFPHYKSCFTTNMIDGRRL 185
>12383
          Length = 782

 Score = 29.3 bits (64), Expect = 9.0,   Method: Compositional matrix adjust.
 Identities = 25/85 (29%), Positives = 46/85 (54%), Gaps = 3/85 (3%)
 Frame = +1

Query: 380 TLRKAETLPEVEAELAQRVAALSKAEERHGNIEE--RLRQMEAQLEE-KNQELQRARQRE 436
           T R   T  EV+  +AQR A++S AEER   I +   +  ++A  ++ K++ L       
Sbjct: 130 TWRS*PTSGEVQIAMAQREASVSLAEERTREILQTGHVAGLQASADDLKHKLLTVMSNAF 309

Query: 437 KMNEEHNKRLSDTVDKLLSESNERL 461
             ++E+  +LSD +D +  + N+R+
Sbjct: 310 TESDENMNKLSDRLDSIQQQENDRM 384
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|21312036|ref|NP_081806.1| RUN and FYVE domain
containing 3 [Mus musculus]
         (469 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

07440                                                                  36   0.033
07872                                                                  30   1.6  
25829                                                                  28   8.6  
>07440
          Length = 656

 Score = 35.8 bits (81), Expect = 0.033,   Method: Compositional matrix adjust.
 Identities = 20/89 (22%), Positives = 47/89 (52%), Gaps = 1/89 (1%)
 Frame = -3

Query: 128 SFWGPLELVEKLVPEAAEITASVKDLPGLKTPVGRGRAWLRLALMQKKLSEYMKALINKK 187
           +FW    +V++   +  ++   ++ L  + + +G  RAW+RLA+    ++ Y+ ++    
Sbjct: 366 NFW---HVVKRFTHK--DVXVQLRQLSQINSDIGLCRAWVRLAVNDGLMASYLASMTADT 202

Query: 188 ELLSEFYEVNALMME-EEGAIIAGLLVGL 215
           + +  FY+  A +++ E+  I+   L GL
Sbjct: 201 KAMVGFYQSWAYLLDYEQPEILRNHLTGL 115
>07872
          Length = 2096

 Score = 30.4 bits (67), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 16/39 (41%), Positives = 21/39 (53%)
 Frame = +2

Query: 386 EKQDALVSLRQQLDDLRALKHELAFKLQSSDLGVKQKSE 424
           E Q  LV+LRQ  D +R   H + FK+  S  G  QK +
Sbjct: 740 EGQPFLVTLRQCYD-IRVAYHTMVFKMAQSGAGTDQKRD 853
>25829
          Length = 543

 Score = 28.1 bits (61), Expect = 8.6,   Method: Compositional matrix adjust.
 Identities = 24/96 (25%), Positives = 45/96 (46%)
 Frame = +3

Query: 219 DANFCMKGEDLDSQVGVIDFSMYLKDGNSSKGSEGDGQITAILDQKNYVEELNRHLNATV 278
           DA    K E++ S +  +D +        ++ +E   ++  +  Q   +EE  +HL+   
Sbjct: 63  DAVISHKDEEIQSLLAELDQANSRCSQLQNQDAESSRELRNLTRQHVRLEEEKKHLSRDY 242

Query: 279 NNLQTKVDLLEKSNTKLTEELAVANNRIITLQEEME 314
             L+ K+ LL +   +L ++LA     +  LQE ME
Sbjct: 243 ATLEQKMQLLTEEKRQLQDQLAETKKEVSRLQECME 350
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|32441290|ref|NP_081409.1| lunapark isoform a [Mus
musculus]
         (425 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

27614                                                                  36   0.033
>27614
          Length = 424

 Score = 35.8 bits (81), Expect = 0.033,   Method: Compositional matrix adjust.
 Identities = 15/19 (78%), Positives = 15/19 (78%)
 Frame = +3

Query: 294 AYCFFLNPARKTRPQAPRL 312
           AYC  LNPARK RP APRL
Sbjct: 3   AYCGILNPARKERPVAPRL 59
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|25188204|ref|NP_082145.1| polyribonucleotide
nucleotidyltransferase 1 [Mus musculus]
         (783 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

28259                                                                  37   0.037
>28259
          Length = 350

 Score = 36.6 bits (83), Expect = 0.037,   Method: Composition-based stats.
 Identities = 17/40 (42%), Positives = 23/40 (57%)
 Frame = -2

Query: 358 RCDGRDLTSLRNISCEVDMFKTLHGSALFQRGQTQVLCTV 397
           R DGR    LR I C + +F+   GSA  ++G T+VL  V
Sbjct: 268 RIDGRRPHELRKIECRLGVFRQADGSAYIEQGNTKVLAAV 149
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|13277352|ref|NP_077778.1| phosducin [Mus musculus]
         (244 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

25631                                                                  35   0.039
>25631
          Length = 442

 Score = 34.7 bits (78), Expect = 0.039,   Method: Compositional matrix adjust.
 Identities = 22/100 (22%), Positives = 58/100 (58%)
 Frame = -2

Query: 40  DSIPPSKKEILRQMSSPQSRDDSKERMSRKMSIQEYELIHQDKEDESCLRKYRRQCMQDM 99
           D I     +++++ +    +D  ++++   MS+ E + + +D EDE+ L +YR++ + +M
Sbjct: 291 DQIQALMNDVIQRRTDLPPQDGQRDKVIDDMSLDELDEL-EDSEDEAVLEQYRQRRIAEM 115

Query: 100 HQKLSFGPRYGFVYELETGEQFLETIEKEQKVTTIVVNIY 139
            +  +   R+G V E+ +G++++  + K  +   +V+++Y
Sbjct: 114 -RATAEKARFGSVREI-SGQEYVNEVTKAGEGIWVVLHLY 1
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|21311867|ref|NP_080894.1| coiled-coil domain
containing 56 [Mus musculus]
         (108 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

04683                                                                  33   0.041
04617                                                                  27   1.7  
04886                                                                  26   3.8  
17412                                                                  26   5.2  
06879                                                                  25   9.8  
>04683
          Length = 1256

 Score = 32.7 bits (73), Expect = 0.041,   Method: Compositional matrix adjust.
 Identities = 25/68 (36%), Positives = 42/68 (61%), Gaps = 4/68 (5%)
 Frame = -3

Query: 21   QRIDPSRE--KLTPAQLQFMRQVQLAQWQ--KTLPQRRTRNIMTGLGIGALVLAIYGYTF 76
            +++D S+E  KL+ +   F+R+++       K +   R +N + GLG+G  VL+IY Y+ 
Sbjct: 1092 EKVDMSKEFSKLSESDKYFVRKLEKMNLDRAKDMKTMRRKNWILGLGLGVGVLSIYFYSM 913

Query: 77   YSVAQERF 84
            Y+V QERF
Sbjct: 912  YAVRQERF 889
>04617
          Length = 1020

 Score = 27.3 bits (59), Expect = 1.7,   Method: Compositional matrix adjust.
 Identities = 10/23 (43%), Positives = 14/23 (60%)
 Frame = -3

Query: 13  KNGNAPFAQRIDPSREKLTPAQL 35
           KNGN PF+Q  + S  ++T   L
Sbjct: 859 KNGNHPFSQSTNESHTRMTSTML 791
>04886
          Length = 1301

 Score = 26.2 bits (56), Expect = 3.8,   Method: Composition-based stats.
 Identities = 11/32 (34%), Positives = 18/32 (56%)
 Frame = -3

Query: 46  WQKTLPQRRTRNIMTGLGIGALVLAIYGYTFY 77
           W  T+ +R    ++T + +G  VL  YG+ FY
Sbjct: 459 WSDTILKRSCCFLVTSMRLGWCVLFSYGWVFY 364
>17412
          Length = 540

 Score = 25.8 bits (55), Expect = 5.2,   Method: Compositional matrix adjust.
 Identities = 13/38 (34%), Positives = 19/38 (50%)
 Frame = -2

Query: 46  WQKTLPQRRTRNIMTGLGIGALVLAIYGYTFYSVAQER 83
           WQ  +  +RTR        G+ VL +   +F +VA ER
Sbjct: 416 WQVLMTSQRTRCASLATPAGSPVLCLKSRSFQAVAMER 303
>06879
          Length = 698

 Score = 24.6 bits (52), Expect = 9.8,   Method: Compositional matrix adjust.
 Identities = 10/23 (43%), Positives = 14/23 (60%)
 Frame = -2

Query: 41  VQLAQWQKTLPQRRTRNIMTGLG 63
           VQL  WQKT P +R +  +T + 
Sbjct: 367 VQLKPWQKTWPMKRWQQFITSMD 299
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|167736371|ref|NP_663375.3| ubiquitination factor E4A
[Mus musculus]
         (1028 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

34916                                                                  37   0.042
01281                                                                  30   7.2  
>34916
          Length = 315

 Score = 37.0 bits (84), Expect = 0.042,   Method: Composition-based stats.
 Identities = 25/72 (34%), Positives = 36/72 (50%), Gaps = 1/72 (1%)
 Frame = +3

Query: 952  DEFLDPIMSTLMSDPVVLPSSRVTVDRSTIARHLLSDQT-DPFNRSPLTMDQIRPNTELK 1010
            +EFL PI   +M DPV+  +   T D+  I   L S +   P   + LT   + PN  LK
Sbjct: 90   NEFLCPITMEIMRDPVI-AADGYTYDQGAIRAWLESGKDRSPMTNAVLTHKHLTPNRTLK 266

Query: 1011 EKIQRWLAERKQ 1022
              IQ+ L + K+
Sbjct: 267  MLIQKHLEQSKK 302
>01281
          Length = 1071

 Score = 29.6 bits (65), Expect = 7.2,   Method: Composition-based stats.
 Identities = 22/53 (41%), Positives = 26/53 (49%)
 Frame = -2

Query: 663 IFTGSIERMKNPHLRAKLAEVLEAVMPHLDQTPSPLVSSVFHRKRVFCNFPYA 715
           I  GS E+   P  R+  AE+  A  P L + PSPLVSS        C FP A
Sbjct: 317 ISAGSAEKTMTPR*RS--AEMPSAAEPWLVKPPSPLVSS--------CIFPXA 189
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|11528518|ref|NP_071313.1| synaptic vesicle
glycoprotein 2 a [Mus musculus]
         (742 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

12029                                                                  36   0.043
27746                                                                  36   0.065
08005                                                                  36   0.069
08272                                                                  33   0.41 
08342                                                                  33   0.59 
17824                                                                  31   2.2  
26669                                                                  29   5.5  
05235                                                                  29   8.0  
>12029
          Length = 605

 Score = 36.2 bits (82), Expect = 0.043,   Method: Compositional matrix adjust.
 Identities = 38/151 (25%), Positives = 60/151 (39%), Gaps = 5/151 (3%)
 Frame = +3

Query: 319 GWSFQMG----SAYQFHSWRVFVLVCAFPSVFAIGALTTQPESPRFFLENGKHDEAWMVL 374
            W+  M      A+Q   W    ++ +   V  +      PES R+    G+  EA  V+
Sbjct: 195 AWAIAMALYALVAWQLPDWSYLHIINSLIGVPFLLTWFVIPESARWLATKGRLQEAEAVI 374

Query: 375 KQVHDTNMRA-KGHPERVFSVTHIKTIHQEDELIEIQSDTGTWYQRWGVRALSLGGQVWG 433
            +V   N RA   H  +      +K +  +DE    Q    T+   +  R L++      
Sbjct: 375 ARVARVNRRAVPAHTAQT-----LKRV-ADDESKARQGRRYTYLDVYRGRRLAMT----- 521

Query: 434 NFLSCFSPEYRRITLMMMGVWFTMSFSYYGL 464
                        TL++  +WFTMSFSYYG+
Sbjct: 522 -------------TLILNFIWFTMSFSYYGM 575
>27746
          Length = 544

 Score = 35.8 bits (81), Expect = 0.065,   Method: Compositional matrix adjust.
 Identities = 30/147 (20%), Positives = 56/147 (38%), Gaps = 5/147 (3%)
 Frame = +2

Query: 325 GSAYQFHSWRVFVLVCAFPSVFAIGALTTQPESPRFFLENGKHDEAWMVLKQVHDTNMRA 384
           G A+    WR   ++   P +  +      PESPR+ ++  +  EA +++ +    N   
Sbjct: 119 GIAWFVRDWRYLDIIVTSPVLLYLSYWCLIPESPRWLIQKQRFXEAQVIINKAAKVN--- 289

Query: 385 KGHPERVFSVTHIKTIHQEDELI----EIQSDTGTWYQRWGVRALSLGGQVWG-NFLSCF 439
                +V     +K   Q+  +       + ++G    RW V        + G  F+ CF
Sbjct: 290 -----KVTPPPDLKLTQQDSHVTGCRDNRKDNSGGGRGRWVVCEFLSSKMLLGRTFVVCF 454

Query: 440 SPEYRRITLMMMGVWFTMSFSYYGLTV 466
           +             WF +S  YY L++
Sbjct: 455 N-------------WFVVSLVYYALSL 496
>08005
          Length = 593

 Score = 35.8 bits (81), Expect = 0.069,   Method: Composition-based stats.
 Identities = 28/75 (37%), Positives = 40/75 (53%), Gaps = 3/75 (4%)
 Frame = +3

Query: 168 LYFVLGLALMADGVEVFVVGFVLPSAEKDMCLSD---SNKGMLGLIVYLGMMVGAFLWGG 224
           L  +LG   + D V + +V  VLP   +D+  SD   S+ G+L  +  L   + A + G 
Sbjct: 24  LIVILGTVTL-DAVGIGLVMPVLPGLLRDIVHSDSIASHYGVLLALYALMQFLCAPVLGA 200

Query: 225 LADRLGRRQCLLISL 239
           L+DR GRR  LL SL
Sbjct: 201 LSDRFGRRPVLLASL 245
>08272
          Length = 1326

 Score = 33.1 bits (74), Expect = 0.41,   Method: Compositional matrix adjust.
 Identities = 26/111 (23%), Positives = 52/111 (46%), Gaps = 7/111 (6%)
 Frame = +1

Query: 597 VYFVSFLGTLAVLPGNIVSALLMDKIGRLRMLAGSSVLSCVSCFFLSFGNSESAMIALLC 656
           V+   FL ++  +P  + ++LL+  +GR    +   +L+ ++ F +   +  ++  A   
Sbjct: 661 VFLNMFLLSVVEVPLTLATSLLVIYVGRRWTGSMFFLLASLTGFGILIADRTASDEAKGT 840

Query: 657 LFGGVSI-------ASWNALDVLTVELYPSDKRTTAFGFLNALCKLAAVLG 700
           +   V+I       A+W  +   TVELYP+  RT   G  N   ++  +L 
Sbjct: 841 IISAVAICSKLFIAAAWTCMQTFTVELYPTVIRTLGLGAANTAARVGGILA 993
>08342
          Length = 1799

 Score = 32.7 bits (73), Expect = 0.59,   Method: Compositional matrix adjust.
 Identities = 20/68 (29%), Positives = 28/68 (41%), Gaps = 2/68 (2%)
 Frame = -2

Query: 444 RRITLMMMGVWFTMSFSYYGLTVWFPDMIRHLQAVDYAARTKVFPGERVEH--VTFNFTL 501
           RR   M M  W +M  SY    ++FP  ++      Y   T + PG R +H  VT N   
Sbjct: 724 RRDDYMTMVAWVSMPHSY---VIFFPLSVKSNLIYSYFESTDILPGYRSDHSIVTLNLKF 554

Query: 502 ENQIHRGG 509
                + G
Sbjct: 553 GKTCKKKG 530
>17824
          Length = 450

 Score = 30.8 bits (68), Expect = 2.2,   Method: Composition-based stats.
 Identities = 15/39 (38%), Positives = 21/39 (53%), Gaps = 1/39 (2%)
 Frame = -2

Query: 333 WRVFVLVCAFPSVFAIGALTTQPESPRFFL-ENGKHDEA 370
           W +     A PS+  +  +   PESPRF L + GK +EA
Sbjct: 242 WPLLFAFNALPSIMCLILMPFCPESPRFLLIKQGKDEEA 126
>26669
          Length = 515

 Score = 29.3 bits (64), Expect = 5.5,   Method: Composition-based stats.
 Identities = 17/50 (34%), Positives = 24/50 (48%)
 Frame = +3

Query: 169 YFVLGLALMADGVEVFVVGFVLPSAEKDMCLSDSNKGMLGLIVYLGMMVG 218
           + VLG   +A G EV     VL   ++  CLSDS    +G +    + VG
Sbjct: 333 HVVLGEVGLAHGAEVRKELLVLRDVQRQFCLSDSRSPHIGHVSAFSIAVG 482
>05235
          Length = 944

 Score = 28.9 bits (63), Expect = 8.0,   Method: Compositional matrix adjust.
 Identities = 19/61 (31%), Positives = 34/61 (55%)
 Frame = -2

Query: 651 MIALLCLFGGVSIASWNALDVLTVELYPSDKRTTAFGFLNALCKLAAVLGISIFTSFVGI 710
           +IA +C     S+  +N+  +  V +Y S  +  A  F N+L KLA + G+++++   GI
Sbjct: 490 VIANIC-----SVTGFNS--IYQVPVY-SASKAXALSFTNSLAKLAHITGVTVYSINPGI 335

Query: 711 T 711
           T
Sbjct: 334 T 332
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|82951323|ref|XP_903526.1| PREDICTED: similar to
CG8777-PA isoform 2 [Mus musculus]
         (1563 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

04645                                                                  37   0.045
28154                                                                  37   0.050
03857                                                                  37   0.057
35264                                                                  33   0.90 
27726                                                                  31   4.1  
18157                                                                  31   4.9  
01414                                                                  30   7.6  
>04645
          Length = 1075

 Score = 37.4 bits (85), Expect = 0.045,   Method: Compositional matrix adjust.
 Identities = 24/87 (27%), Positives = 37/87 (42%)
 Frame = +3

Query: 578 GQHSQAVADLQAALRADPKDCNCWESLGEAYLSRGGYTTALKSFMKASELNPDSTYSVFK 637
           G+   A+     A++++P     +   G AYL  G    A+    KA ELNPDS      
Sbjct: 486 GRLEDAIGFFTDAIKSNPTSALLYAKRGSAYLKMGKPKKAIHDCSKAIELNPDSAQGYKW 665

Query: 638 VAAIQQILGRYSEAIAQYQLIIKMKED 664
                ++LG + E+     L  K+  D
Sbjct: 666 RGKAHKLLGHWEESYHDLTLACKLDYD 746

 Score = 33.9 bits (76), Expect = 0.57,   Method: Compositional matrix adjust.
 Identities = 15/48 (31%), Positives = 28/48 (58%)
 Frame = +3

Query: 287 KYEDAVRHLTEGLKESPVCIAGWCHLAEAQVKMHRPKEAILSCNQALK 334
           + EDA+   T+ +K +P     +     A +KM +PK+AI  C++A++
Sbjct: 489 RLEDAIGFFTDAIKSNPTSALLYAKRGSAYLKMGKPKKAIHDCSKAIE 632
>28154
          Length = 374

 Score = 37.4 bits (85), Expect = 0.050,   Method: Compositional matrix adjust.
 Identities = 25/69 (36%), Positives = 42/69 (60%), Gaps = 1/69 (1%)
 Frame = +1

Query: 572 LYHLKAGQHSQAVADLQAALRADPKDCNCWESLGEAYLSRGGYT-TALKSFMKASELNPD 630
           L++L +G++++AV   QAAL+A PKD   W  LG A L+ GG +  A+ ++  A +L+P 
Sbjct: 121 LFNL-SGEYNKAVDCFQAALQARPKDALLWNKLG-ATLANGGRSEEAVDAYHNALQLSPG 294

Query: 631 STYSVFKVA 639
              S + + 
Sbjct: 295 FIRSRYNLG 321

 Score = 32.0 bits (71), Expect = 1.9,   Method: Compositional matrix adjust.
 Identities = 27/109 (24%), Positives = 44/109 (40%)
 Frame = +1

Query: 787 YRQVQHLAETGSSMSDLTELLEKSLHCLKKAVRLDSNNHLHWNALGVVACYRGVGNYALA 846
           Y +VQ+L  +   M+   E ++  + C                 LGV+  +   G Y  A
Sbjct: 28  YEEVQNLYLSAVQMAAPQESVDADVQC----------------NLGVL--FNLSGEYNKA 153

Query: 847 QHCFIKSIQAEQINAAAWTNLGVLYLATENIEQAHEAFKMAQSLDPSYL 895
             CF  ++QA   +A  W  LG         E+A +A+  A  L P ++
Sbjct: 154 VDCFQAALQARPKDALLWNKLGATLANGGRSEEAVDAYHNALQLSPGFI 300
>03857
          Length = 1696

 Score = 37.0 bits (84), Expect = 0.057,   Method: Compositional matrix adjust.
 Identities = 21/71 (29%), Positives = 35/71 (49%)
 Frame = +1

Query: 575 LKAGQHSQAVADLQAALRADPKDCNCWESLGEAYLSRGGYTTALKSFMKASELNPDSTYS 634
           LK  ++++A+   Q  L ADP +       G+A+     Y TAL SF KA   NPD    
Sbjct: 655 LKLNKYNEALEYCQEVLEADPDNSKAQYRQGQAHAGNKDYETALASFQKALAANPDDKGI 834

Query: 635 VFKVAAIQQIL 645
             ++  +++ +
Sbjct: 835 KLEIQKVKRTV 867

 Score = 33.5 bits (75), Expect = 0.69,   Method: Compositional matrix adjust.
 Identities = 17/52 (32%), Positives = 30/52 (57%)
 Frame = +1

Query: 396 CLNTGAVDKATKIMEDLVTSYPDLAEAHALEGRVHFTKKDYVQAEVSFQRAL 447
           CL     ++A +  ++++ + PD ++A   +G+ H   KDY  A  SFQ+AL
Sbjct: 652 CLKLNKYNEALEYCQEVLEADPDNSKAQYRQGQAHAGNKDYETALASFQKAL 807
>35264
          Length = 867

 Score = 33.1 bits (74), Expect = 0.90,   Method: Compositional matrix adjust.
 Identities = 19/67 (28%), Positives = 30/67 (44%)
 Frame = +3

Query: 614 YTTALKSFMKASELNPDSTYSVFKVAAIQQILGRYSEAIAQYQLIIKMKEDYVPALKGLG 673
           Y  AL+ +  A  L P         AA   +L +Y E +   Q  +++   +V      G
Sbjct: 87  YKEALECYTCAINLCPSCAAYYGNRAATYMMLKKYREGLKDAQQAVQLDPTFVKGYIREG 266

Query: 674 ECHLLLG 680
           +CHL+LG
Sbjct: 267 KCHLMLG 287
>27726
          Length = 366

 Score = 30.8 bits (68), Expect = 4.1,   Method: Composition-based stats.
 Identities = 18/51 (35%), Positives = 29/51 (56%)
 Frame = -2

Query: 843 YALAQHCFIKSIQAEQINAAAWTNLGVLYLATENIEQAHEAFKMAQSLDPS 893
           Y  A+  + + I+ +  N    TNLGVLY   E I +A E+++ A S++ S
Sbjct: 323 YMEAETLYKRVIEIDPRNMLYHTNLGVLYHRWEKIPEAMESYQTAISINFS 171
>18157
          Length = 1102

 Score = 30.8 bits (68), Expect = 4.9,   Method: Composition-based stats.
 Identities = 16/47 (34%), Positives = 21/47 (44%)
 Frame = -3

Query: 571 GLYHLKAGQHSQAVADLQAALRADPKDCNCWESLGEAYLSRGGYTTA 617
           GL H   G H +    +  A  + PK   CWE+      SRGG  +A
Sbjct: 797 GLLHEILGSHIRPCKTISMARTSXPKSQACWETYHPTPSSRGGTCSA 657
>01414
          Length = 1073

 Score = 30.0 bits (66), Expect = 7.6,   Method: Composition-based stats.
 Identities = 15/36 (41%), Positives = 18/36 (50%)
 Frame = +3

Query: 913 TMDLFRHTTELSMHTEGAIGYAYWVCTTLQDKSNRE 948
           T+ LF H T       GA+  A+WV  T   K NRE
Sbjct: 81  TV*LFSHPTLPGSSAHGALH*AFWVAGTFTTKENRE 188
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|51491821|ref|NP_080637.1| plakophilin 4 isoform 1
[Mus musculus]
         (1190 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

22653                                                                  37   0.049
06072                                                                  32   1.8  
>22653
          Length = 1347

 Score = 37.0 bits (84), Expect = 0.049,   Method: Composition-based stats.
 Identities = 30/100 (30%), Positives = 52/100 (52%), Gaps = 2/100 (2%)
 Frame = +3

Query: 535 MLQHQFPSVQANAAAYLQHLCFGDNKVKMEVYR--LGGIKHLVDLLDHRVLEVQKNACGA 592
           +L++Q P VQA +AA+    C  + K   E+ R  +GG++ +V LL     EV    C A
Sbjct: 12  LLKNQNPDVQA-SAAWAICPCIENAKDAGEMVRSFVGGLELIVSLLKSEDKEVLAAVCAA 188

Query: 593 LRNLVFGKSTDENKIAMKNVGGIPALLRLLRKSIDAEVRE 632
           + N+    + DE  +A+    G+  +L  L  + D ++R+
Sbjct: 189 IANI----AKDEENLAVITDHGVVPMLAKLTLTTDDKLRQ 296
>06072
          Length = 1397

 Score = 31.6 bits (70), Expect = 1.8,   Method: Compositional matrix adjust.
 Identities = 21/94 (22%), Positives = 40/94 (42%)
 Frame = +1

Query: 532 VIHMLQHQFPSVQANAAAYLQHLCFGDNKVKMEVYRLGGIKHLVDLLDHRVLEVQKNACG 591
           ++ +L H   SV A A   + ++  GD+     +     +  L+ LL      ++K AC 
Sbjct: 808 LVELLMHNHQSVVAAALRVVGNIVTGDDSQTQVILSCSALPCLLHLLSSNKETIRKEACW 987

Query: 592 ALRNLVFGKSTDENKIAMKNVGGIPALLRLLRKS 625
            + N+  G       +   N+   P L+ +L K+
Sbjct: 988 TISNITAGNRNQIQDVIDTNI--FPVLIEILGKA 1083
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|82934973|ref|XP_484070.2| PREDICTED: GPR158-like 1
receptor isoform 1 [Mus musculus]
         (2293 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

38764                                                                  32   0.051
25697                                                                  32   2.8  
14057                                                                  32   3.1  
30893                                                                  32   4.0  
>38764
          Length = 1159

 Score = 32.3 bits (72), Expect(2) = 0.051,   Method: Composition-based stats.
 Identities = 19/68 (27%), Positives = 29/68 (42%), Gaps = 7/68 (10%)
 Frame = +3

Query: 227 VKLSPPFLECHEGQLRPGWLVTVSATFYGLKPDLTP-------EVRGQVQMDIDLQSVDI 279
           V +S P+ +C        W+VT S+      P  +P          G   MDI+ + +D+
Sbjct: 354 VLISQPYFDCDRSNR---WIVTASSPVVEYMPRYSPWLHLRRARFTGVTTMDIEFERLDM 524

Query: 280 NQCASGPG 287
           NQC    G
Sbjct: 525 NQCPLAEG 548

 Score = 24.3 bits (51), Expect(2) = 0.051,   Method: Composition-based stats.
 Identities = 9/15 (60%), Positives = 9/15 (60%)
 Frame = +1

Query: 310 FVLGRYLCRCRPGFY 324
           F  G Y C C PGFY
Sbjct: 628 FQAGSYQCVCLPGFY 672
>25697
          Length = 470

 Score = 32.0 bits (71), Expect = 2.8,   Method: Compositional matrix adjust.
 Identities = 14/53 (26%), Positives = 28/53 (52%), Gaps = 1/53 (1%)
 Frame = +1

Query: 1741 SQQPDTPNTEKLKDELQEHGSSRPIEVC-PWEAEEVPTGEKAKICPWELNEGT 1792
            + +P     +K  +ELQ+HG+   + VC P  ++E    E   +  W+ ++G+
Sbjct: 13   TDRPTDSTLDKFIEELQKHGARHVVRVCDPTYSKEKLETEGIDVMDWQFDDGS 171
>14057
          Length = 1377

 Score = 32.0 bits (71), Expect = 3.1,   Method: Compositional matrix adjust.
 Identities = 20/77 (25%), Positives = 34/77 (44%), Gaps = 14/77 (18%)
 Frame = +2

Query: 1741 SQQPDTPNTEKLKDELQEHGSSRPIEVC-PWEAEEVPTGEKAKICPWELNEGT------V 1793
            + +P     +K  +ELQ+HG+   + VC P  + EV       +  W+ ++G+      V
Sbjct: 722  TDRPTDSTIDKYIEELQKHGAKHVVRVCDPTYSREVLQKAGIDVLDWQFDDGSPPPNEVV 901

Query: 1794 GK-------GLEREPGC 1803
            G          + EPGC
Sbjct: 902  GNWFNLLKARFKEEPGC 952
>30893
          Length = 490

 Score = 31.6 bits (70), Expect = 4.0,   Method: Composition-based stats.
 Identities = 26/99 (26%), Positives = 34/99 (34%), Gaps = 1/99 (1%)
 Frame = +2

Query: 278 DINQCASGPGWYSNTHLCDLNSTQCVPLESQGFVLGRYLCRCRPGFYXXXXXXXXXXXXT 337
           DIN+C S P        C  N   C  L      +GRY C C PG+              
Sbjct: 194 DINECFSAP--------CQ-NGATCTDL------IGRYTCTCEPGYQGLNCEYDIDECHN 328

Query: 338 QAAGQFGSPQDSLGKL-LRCQPCPEGCTSCLDATPCLVE 375
           Q     G+  D +      C P  +G    +D   CL +
Sbjct: 329 QPCLNGGTCHDLVNTYKCSCPPGTQGLLCEMDENDCLFD 445
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|116089273|ref|NP_032138.3| guanosine diphosphate
(GDP) dissociation inhibitor 2 [Mus musculus]
         (445 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

09168                                                                  35   0.053
>09168
          Length = 1065

 Score = 35.0 bits (79), Expect = 0.053,   Method: Compositional matrix adjust.
 Identities = 31/107 (28%), Positives = 48/107 (44%), Gaps = 7/107 (6%)
 Frame = +3

Query: 343 VAAQGKYIAIVSTTVETKEPEKEIRPALELLEPIEQKFVSISDLFV----PKDLGTDSQI 398
           ++ Q KY A +   + TK   K    A   L+P++ + + + D F     P DLGT    
Sbjct: 504 LSEQLKYCAQIVKELHTK---KHHAIAWPFLKPVDTENLGLDDYFTIIKKPMDLGTVKTK 674

Query: 399 FISRAYDATTHFETTCDDIKDIYK---RMTGSEFDFEEMKRKKNDIY 442
             +R Y+    FET   D++ I+    R    E D   M RK  D++
Sbjct: 675 MENREYNTPKEFET---DMRLIFSNCYRYNSPETDVVMMARKLQDVF 806
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|94400369|ref|XP_001001861.1| PREDICTED: similar to
rat GCP360 isoform 9 [Mus musculus]
         (3201 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

18090                                                                  38   0.057
35150                                                                  33   2.3  
24182                                                                  31   8.0  
>18090
          Length = 772

 Score = 38.1 bits (87), Expect = 0.057,   Method: Compositional matrix adjust.
 Identities = 40/133 (30%), Positives = 68/133 (51%), Gaps = 18/133 (13%)
 Frame = +1

Query: 221 LRVMQRKLEEHEEALLGRAQVVDLLQKELTSAE---QRN-----------QVLSQQLQLL 266
           +R+ ++K ++  + L G+ +V++LLQKE    E   Q N           QV S+QL L+
Sbjct: 379 IRMFEQKWKDTNDVLEGKVKVIELLQKESGVKEKELQENKESIKVLREKLQVTSEQLMLV 558

Query: 267 EAEHNTLKNTMETERQ----ESKTLMEKVELEVAERKLSFHNLQEEMHQLQGQLERAGQA 322
           +A     +N  + E+Q    + K   EK E EV+E++L    L+  + +L+    +A   
Sbjct: 559 QANFVDQENQWKEEKQRLEVKFKDTAEKHEHEVSEKELQVQTLKSSLTELESAYSQAA-- 732

Query: 323 QADLETQYSALQQ 335
                +QYSALQ+
Sbjct: 733 -----SQYSALQE 756
>35150
          Length = 410

 Score = 32.7 bits (73), Expect = 2.3,   Method: Compositional matrix adjust.
 Identities = 17/61 (27%), Positives = 34/61 (55%)
 Frame = +2

Query: 1350 GQKEEEVNYLYGQLSEKEQTLTTVQTEMVEQERLIKALHTQLEMQAKEHEERLKQAQVEI 1409
            G+ E+ +N + GQ+ E E+ ++ +Q  + ++E  +K  HT+L+        R  +  VE+
Sbjct: 14   GKLEDHLNKIIGQIKEIEENISRLQKAIADKEAPMKLAHTRLDT-------RTNRPNVEL 172

Query: 1410 C 1410
            C
Sbjct: 173  C 175
>24182
          Length = 1269

 Score = 30.8 bits (68), Expect = 8.0,   Method: Compositional matrix adjust.
 Identities = 39/135 (28%), Positives = 70/135 (51%), Gaps = 3/135 (2%)
 Frame = +2

Query: 2531 EAEKQSLQMSSDALQKEKQGLSKEIKNLQTQLTALQEEGTLGVYHAQLKAKEEELQRLNM 2590
            EA  Q+++ S  +LQKE +   +  K+L   LT+LQ+             +E EL+ +  
Sbjct: 158  EASLQTMEESLKSLQKEHE---ENEKSLMDSLTSLQQSAA---------DRETELEEV-- 295

Query: 2591 ALSSSQKRTADLEEELVCVQKEATRK---VSEIEDQLKKELKHLHHDAGIMRNETETAEE 2647
             + S +    DLE++++ +Q E + K   +S++E Q K++L+ L   A  +R +    E+
Sbjct: 296  -IDSHKTHXTDLEDKVLSLQNEVSLKDTVLSDMESQCKQQLEDLQSSAAQVRQQ---LED 463

Query: 2648 RVAELARDLVEMEQK 2662
            RV  L   + E+E K
Sbjct: 464  RVCSLKNHITELEDK 508
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|28395023|ref|NP_058661.1| NCK-associated protein 1
[Mus musculus]
         (1128 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

12906                                                                  37   0.065
27341                                                                  30   7.9  
>12906
          Length = 674

 Score = 36.6 bits (83), Expect = 0.065,   Method: Compositional matrix adjust.
 Identities = 27/86 (31%), Positives = 45/86 (52%)
 Frame = -3

Query: 801 SNGHIAYFPAMKAFVNLPTENELTFNAEEYSDISEMRSLSELLGPYGMKFLSESLMWHIS 860
           S+ H+   PA++A V LP   ++  + EEY D+S+  S+         KF S+  +W   
Sbjct: 276 SHPHVP-VPALQAAV-LPVTEQILSDGEEYEDVSQQESVVCRRSTKTQKFQSKYKVW--- 112

Query: 861 SQVAELKKLVVENVDVLTQMRTSFDK 886
            +V  LK LV+  + +LT + T F +
Sbjct: 111 LKVLILKTLVIVVITLLTMIVTLFHQ 34
>27341
          Length = 380

 Score = 29.6 bits (65), Expect = 7.9,   Method: Composition-based stats.
 Identities = 13/35 (37%), Positives = 22/35 (62%)
 Frame = -2

Query: 263 IFGFILCHGMLNTEATALNLWKLALQSSSCLSLFR 297
           +FGFIL HG+L       ++ +L  ++S C++ FR
Sbjct: 337 LFGFILIHGLLRYITRKCSV*RLH*EASHCINRFR 233
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|61743961|ref|NP_033773.1| AHNAK nucleoprotein isoform
1 [Mus musculus]
         (5656 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

39267                                                                  39   0.068
>39267
          Length = 456

 Score = 38.5 bits (88), Expect = 0.068,   Method: Composition-based stats.
 Identities = 27/106 (25%), Positives = 49/106 (46%), Gaps = 4/106 (3%)
 Frame = +1

Query: 31  DGVFVQEVMQNSPAARTGVVKEGDQIVGATIYFDNLQSGEVTQLLNTMGHHTVGLKL--H 88
           DG++V ++    PA+ +G +  GD+I   TI +DN+   +   +L+    + V L L  H
Sbjct: 148 DGIYVSQLHNRGPASESGKIHVGDRIQSVTIAYDNIVYEDALTILSYASPYPVLLTLQKH 327

Query: 89  RKGDRSPEPG--QTWTHEVFSSRSSEVVLSGDDEDYQRIYTTKIKP 132
           R        G  +   H ++ S+S + +        QRI++    P
Sbjct: 328 RSASAHGHTGSREQLNHPMYRSQSLDAL--------QRIHSDPADP 441
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|21312960|ref|NP_080439.1| plakophilin 2 [Mus
musculus]
         (795 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

21785                                                                  36   0.071
13565                                                                  33   0.47 
01691                                                                  31   1.6  
06072                                                                  30   5.0  
>21785
          Length = 958

 Score = 35.8 bits (81), Expect = 0.071,   Method: Compositional matrix adjust.
 Identities = 22/63 (34%), Positives = 36/63 (57%)
 Frame = -1

Query: 344 EARKRVNQLRGIPKLLQLLKLQNEDVQRAACGALRNLVFEDNDNKLEVAELNGVPRLLQV 403
           +AR  V +  G P +L+LLK +   +Q+ A   L  L+ +D +N+  + EL G+ RLL  
Sbjct: 397 QARGSVREYDGFPPILELLKSEYAVIQKLALLTLDRLM-QDVENRSTLRELEGISRLLDF 221

Query: 404 LKQ 406
           L +
Sbjct: 220 LAK 212
>13565
          Length = 882

 Score = 33.1 bits (74), Expect = 0.47,   Method: Compositional matrix adjust.
 Identities = 23/81 (28%), Positives = 37/81 (45%), Gaps = 4/81 (4%)
 Frame = -2

Query: 713 LNNLMQNSYQNARDLLNTGGLQKIMTISIGEGYAPNKASKAASVLLYSLWAHTELHHAYK 772
           L +L Q S Q+ RD L     +++  + + EG+A  +    A    + LW    L HAY 
Sbjct: 635 LTDLRQVS-QDRRDFLQ----REVERVCVEEGFAVGRTFTWAKSAAWLLWMTHLLSHAYS 471

Query: 773 KAQFKKTDF----VNSRTAKA 789
              F +  F    ++SR A+ 
Sbjct: 470 HGNFDRETFPYSELSSRLARG 408
>01691
          Length = 765

 Score = 31.2 bits (69), Expect = 1.6,   Method: Composition-based stats.
 Identities = 12/30 (40%), Positives = 17/30 (56%)
 Frame = +3

Query: 200 RRPPGCGSFSDAVFDNGPLKPTMPTHPPGT 229
           R+PP C   ++  FD+ P    +P HP GT
Sbjct: 660 RQPPNCLKITNFHFDHEPPSRALPLHPTGT 749
>06072
          Length = 1397

 Score = 29.6 bits (65), Expect = 5.0,   Method: Compositional matrix adjust.
 Identities = 22/69 (31%), Positives = 33/69 (47%)
 Frame = +1

Query: 356 PKLLQLLKLQNEDVQRAACGALRNLVFEDNDNKLEVAELNGVPRLLQVLKQTRDLETKKQ 415
           P  ++LL  + EDVQ  A  AL N+  +  + +  V   N +  LLQ+L +T  L   + 
Sbjct: 421 PIFVRLLSSEVEDVQEQAVWALGNIAGDSPECREYVLNENILVPLLQLLSKTTSLSMSRN 600

Query: 416 ITGLLWNLS 424
               L NL 
Sbjct: 601 AVWCLSNLC 627
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|29789144|ref|NP_075605.1| calcium channel,
voltage-dependent, beta 2 subunit [Mus musculus]
         (655 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

13641                                                                  35   0.074
08480                                                                  34   0.15 
20131                                                                  31   1.6  
29636                                                                  29   6.1  
>13641
          Length = 2081

 Score = 35.4 bits (80), Expect = 0.074,   Method: Compositional matrix adjust.
 Identities = 31/139 (22%), Positives = 56/139 (40%), Gaps = 7/139 (5%)
 Frame = +2

Query: 113 FAVRTNVRYSAAQEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEG---CEIGFI 169
             V+    +++  +D++P     +SF+  D LH+  + +  WW  +  K G      G I
Sbjct: 152 MVVKAMFSFNSKLDDNIPCKEAGLSFQQGDILHIVNQEDAIWW--QAYKHGDAKKRAGLI 325

Query: 170 PSPVKLENMRLQHEQRAKQGKFYXXXXXXXXXXXXXDIVPSSRKSTPPSSAIDIDATGLD 229
           PS    E   +  + ++K+G+                 VP  R+       I  +    D
Sbjct: 326 PSRHYHERQEVLRKSKSKEGRHMARSISPCRYSPK---VPKQRRLRKTMYHIVQNGALTD 496

Query: 230 AEENDIPA----NHRSPKP 244
            + ++IPA     H +PKP
Sbjct: 497 FDTDEIPAYDEVEHFTPKP 553
>08480
          Length = 698

 Score = 34.3 bits (77), Expect = 0.15,   Method: Compositional matrix adjust.
 Identities = 20/66 (30%), Positives = 32/66 (48%), Gaps = 3/66 (4%)
 Frame = -1

Query: 128 DVPVPGMAISFEAKDFLHVKEKFNNDWWIG-RLVKEGCE--IGFIPSPVKLENMRLQHEQ 184
           D  +P   + F   D LHV    +++WW   R++ +G E  +G IPS  ++E       +
Sbjct: 413 DSGLPSRGLWFHYGDILHVTNASDDEWWQAKRILPDGKEEGMGIIPSKRRVERKERARLR 234

Query: 185 RAKQGK 190
             K GK
Sbjct: 233 NVKFGK 216
>20131
          Length = 574

 Score = 30.8 bits (68), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 13/38 (34%), Positives = 21/38 (55%), Gaps = 2/38 (5%)
 Frame = -2

Query: 136 ISFEAKDFLHVKEKFNNDWWIGRLVKEGC--EIGFIPS 171
           +S E  + +HV++K    WW G L   G   +IG+ P+
Sbjct: 234 LSLEPGNLIHVRQKSPRGWWEGELQARGQRKKIGWFPA 121
>29636
          Length = 354

 Score = 28.9 bits (63), Expect = 6.1,   Method: Compositional matrix adjust.
 Identities = 17/50 (34%), Positives = 24/50 (48%), Gaps = 4/50 (8%)
 Frame = +1

Query: 126 EDD--VPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEI--GFIPS 171
           EDD  +P   + ISF   D LH  +  +++WW      E   +  G IPS
Sbjct: 103 EDDPYIPCRELGISFLKGDILHAIQLSDSNWWQAHREGEDAHMLAGLIPS 252
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|30519913|ref|NP_848714.1| COMM domain containing 8
[Mus musculus]
         (183 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

13142                                                                  33   0.074
>13142
          Length = 523

 Score = 33.1 bits (74), Expect = 0.074,   Method: Compositional matrix adjust.
 Identities = 18/64 (28%), Positives = 34/64 (53%), Gaps = 9/64 (14%)
 Frame = -3

Query: 95  KSRRNEIKQALLGEIVD---------ISCAQLQDFDWQLKLALSSDKIATLQMPLLNLHL 145
           K+ R+ I + ++  + D         +S  +L DFDW++ +  +SD +A + +P   L L
Sbjct: 242 KNLRDLIGKIIIDNMADWKSQAVGAHVSLPKLADFDWRVDVKTASDTVARMSVPTCILSL 63

Query: 146 DVKE 149
            V+E
Sbjct: 62  QVEE 51
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31981634|ref|NP_598805.2| hypothetical protein
LOC104799 isoform b [Mus musculus]
         (472 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

15444                                                                  35   0.081
11075                                                                  32   0.37 
21286                                                                  29   4.4  
>15444
          Length = 1009

 Score = 34.7 bits (78), Expect = 0.081,   Method: Compositional matrix adjust.
 Identities = 19/69 (27%), Positives = 31/69 (44%)
 Frame = -2

Query: 328 EGTFSSPINLKKTFKIPDKQYVLTXXXXXXXXXXWNDVDALFTTKNWLGYTKKRAPIGFH 387
           EG++ S   L+K FK+PDK++             W++++    T        K+ PIG  
Sbjct: 978 EGSYISADKLRKEFKVPDKRFWWMRVYALAESGSWDELEKFSRT--------KKPPIGME 823

Query: 388 RVVEILHKN 396
             VE   K+
Sbjct: 822 AFVEACMKH 796
>11075
          Length = 2368

 Score = 32.3 bits (72), Expect = 0.37,   Method: Compositional matrix adjust.
 Identities = 44/226 (19%), Positives = 84/226 (37%), Gaps = 3/226 (1%)
 Frame = +2

Query: 164 LEEAVSMHDGNVITAVLIFLKRTLSKEILFRELEVRQVALRHLIHFLKEIGDQKXXXXXX 223
           L +A+   D +++  VLI L+  L +   F  +    +A    I FL+ + + +      
Sbjct: 137 LNKAIDSGDTDLVYTVLIHLRDNLDRSQFFMMIHTMPIAFSLYIQFLR-VQNLEMVENMW 313

Query: 224 XXXXXAEELALSHYREHLNIQDPEKRKEFLK---TCIGLPFSAEDAAHVQDHYTLLERQI 280
                  E+  +      + +  + R   L+    C     S  +  H ++   LL  Q 
Sbjct: 314 EQEDNPLEMGFTKIIRAYDQETLDARVRLLEESGNCFHRVNSTFNEKHCEEENKLLRHQR 493

Query: 281 IIEANDRHLESSGQTDIFRKHPRKASILNMPLVTTLFYACFYHYTESEGTFSSPINLKKT 340
            +E      + +G T            +++ L  T+      H    EG++ S   L+K 
Sbjct: 494 RLE------DETGLT-----------FVDLSLQQTM------HKLTMEGSYISADKLRKE 604

Query: 341 FKIPDKQYVLTXXXXXXXXXXWNDVDALFTTKNWLGYTKKRAPIGF 386
           FK+PDK++             W++++    T        K+ PIG 
Sbjct: 605 FKVPDKRFWWMRVYALAESGSWDELEKFSRT--------KKPPIGM 718
>21286
          Length = 1212

 Score = 28.9 bits (63), Expect = 4.4,   Method: Compositional matrix adjust.
 Identities = 26/102 (25%), Positives = 42/102 (41%), Gaps = 1/102 (0%)
 Frame = +3

Query: 311 PLVTTLFYACFYHYTESEGTFSSPINLKKTFKIP-DKQYVLTXXXXXXXXXXWNDVDALF 369
           P  +  F+ C Y Y  S+   S  I   +  KIP D Q              WND+D + 
Sbjct: 861 PFWSLGFHLCKYGYGSSK-VLSEVIARNRAAKIPYDVQ--------------WNDIDYMD 995

Query: 370 TTKNWLGYTKKRAPIGFHRVVEILHKNSAPVQILQEYVNLVE 411
             K+W  Y    +  G   +V+ LH ++      Q Y+ +++
Sbjct: 996 AYKDWT-YDSNGSYSGLRDIVDDLHAHN------QRYIMIID 1100
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|158711686|ref|NP_065066.2| solute carrier family 12,
member 5 [Mus musculus]
         (1115 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

35370                                                                  36   0.083
08237                                                                  32   1.3  
01597                                                                  32   2.0  
03267                                                                  30   7.2  
>35370
          Length = 628

 Score = 36.2 bits (82), Expect = 0.083,   Method: Compositional matrix adjust.
 Identities = 37/162 (22%), Positives = 71/162 (43%), Gaps = 1/162 (0%)
 Frame = -1

Query: 423 DLRDAQKSIPTGTILAIATTSAVYISSVVLFGACIEGVVLRDKFGEAVN-GNLVVGTLAW 481
           ++++  K++P   I+ I   +  Y    + + A +    + +    AV  GN ++G LAW
Sbjct: 484 EIKNPSKNLPRSIIIGIPLVTLCYALINISYLAAMSAQEMIESEAVAVTFGNRILGALAW 305

Query: 482 PSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAISRDGIVPFLQVFGHGKANGEPTWALLLT 541
             P  + I +F S  G    +L  A RL  A SR+G +  +  + H +    P   L+  
Sbjct: 304 LMPLSVTISTFGSANG----TLFAAGRLCFAASREGHLLDILSYVHVR-RLTPAPGLIFH 140

Query: 542 ACICEIGILIASLDEVAPILSMFFLMCYMFVNLACAVQTLLR 583
           + I    +L  ++D    ++  F    ++F   A     ++R
Sbjct: 139 SLIASAMVLHGTIDS---LIDFFSFTAWIFYGGAMLALIVMR 23
>08237
          Length = 912

 Score = 32.0 bits (71), Expect = 1.3,   Method: Composition-based stats.
 Identities = 13/38 (34%), Positives = 23/38 (60%)
 Frame = +3

Query: 538 LLLTACICEIGILIASLDEVAPILSMFFLMCYMFVNLA 575
           L + AC+C   ++    +++A ILS+ F++CY   N A
Sbjct: 180 LYVVACVCLFMVVGGRREKLAVILSVLFVVCYTIANXA 293
>01597
          Length = 1834

 Score = 31.6 bits (70), Expect = 2.0,   Method: Compositional matrix adjust.
 Identities = 36/147 (24%), Positives = 59/147 (40%), Gaps = 16/147 (10%)
 Frame = -1

Query: 694 LTSQLKAGKGLTIVGSVLEGTFLDNHPQAQRAEESIRRLMEAEKVKG--FCQVVISSNLR 751
           L S      G T + + ++GT  D +PQ    + S++   EA+ V    F Q  I+   +
Sbjct: 802 LASHTDINNGRTKMEAEVQGTPCDMYPQPGCKDSSVQCKTEAQDVHSGVFPQQEINIQHQ 623

Query: 752 DGVSHLIQS----------GGLGGL----QHNTVLVGWPRNWRQKEDHQTWRNFIELVRE 797
             V  ++            G + GL      +++ + WP  W   +D +T+  F  L R 
Sbjct: 622 TQVQDILSDVYPQRESSAQGQMTGLPLPDTRDSLHIVWPHRWEHDKDPETF--FQVLFRL 449

Query: 798 TTAGHLALLVTKNVSMFPGNPERFSEG 824
              G+   LV+     F   PE F E 
Sbjct: 448 QDEGY-RFLVSVLGETFTDVPEIFGEA 371
>03267
          Length = 2120

 Score = 29.6 bits (65), Expect = 7.2,   Method: Compositional matrix adjust.
 Identities = 15/61 (24%), Positives = 28/61 (45%)
 Frame = -1

Query: 779  WRQKEDHQTWRNFIELVRETTAGHLALLVTKNVSMFPGNPERFSEGSIDVWWIVHDGGML 838
            WR  E+H  WR  +++V+ +  G  A+ + ++          F+ G   V  I+ D   +
Sbjct: 1448 WRYAENH*PWRTRVQVVKRSRRGETAISIARS----------FNVGKTQVQNIIKDQNTI 1299

Query: 839  M 839
            M
Sbjct: 1298 M 1296
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6678866|ref|NP_032616.1| mesoderm specific transcript
[Mus musculus]
         (335 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

12287                                                                  34   0.084
35904                                                                  29   3.0  
>12287
          Length = 965

 Score = 33.9 bits (76), Expect = 0.084,   Method: Compositional matrix adjust.
 Identities = 22/79 (27%), Positives = 41/79 (51%)
 Frame = +3

Query: 99  VIALDFLGFGFSDKPRPHQYSIFEQASIVESLLRHLGLQNRRINLLSHDYGDIVAQELLY 158
           VIA   +GFG+SD      ++  E A+++ +L+  LG  ++   +   D+G ++   L  
Sbjct: 75  VIAPSLVGFGWSDAATRVGFNAAEMATVMRNLMLRLG--HKEFFIQGGDWGSVIGSNLAT 248

Query: 159 RYKQNRSGRLTIKSLCLSN 177
            Y +N  G  +  +LC+ N
Sbjct: 249 LYPENVLGYHS--NLCVLN 299
>35904
          Length = 514

 Score = 28.9 bits (63), Expect = 3.0,   Method: Compositional matrix adjust.
 Identities = 21/54 (38%), Positives = 28/54 (51%), Gaps = 3/54 (5%)
 Frame = +2

Query: 91  GLTLRFHRVIALDFLGFGFSDKPRP---HQYSIFEQASIVESLLRHLGLQNRRI 141
           G  LR H V  L  L F  S  PR    H  ++F Q S++E  +RH  + +RRI
Sbjct: 290 GQRLRHHLVGHL--LRFTLSTTPRCCIHHHVALFNQGSMLELFIRHGAVLHRRI 445
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31981575|ref|NP_035199.2| peroxisomal biogenesis
factor 11 beta [Mus musculus]
         (259 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

13857                                                                  33   0.091
>13857
          Length = 484

 Score = 33.5 bits (75), Expect = 0.091,   Method: Compositional matrix adjust.
 Identities = 12/30 (40%), Positives = 19/30 (63%)
 Frame = +1

Query: 203 GHPPLLLDVLRNACNLFIPLDKLGFWRCGP 232
           GH  +++D ++N  +LFIPL  LG+    P
Sbjct: 163 GHKDIVIDTVKNMSDLFIPLTALGYTSLTP 252
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|38146006|ref|NP_083829.1| tetratricopeptide repeat
domain 8 isoform 1 [Mus musculus]
         (505 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

26275                                                                  35   0.093
18279                                                                  33   0.18 
28154                                                                  33   0.26 
27876                                                                  32   0.54 
>26275
          Length = 896

 Score = 34.7 bits (78), Expect = 0.093,   Method: Compositional matrix adjust.
 Identities = 26/84 (30%), Positives = 36/84 (42%), Gaps = 2/84 (2%)
 Frame = +2

Query: 388 DVWYNLGHIAVGIGDTNLAHQCFRLAL--VHNNHHAEAYNNLAVLEMRKGHVEQARALLQ 445
           DVW N+ HI V       A Q +  AL     NH+ E    LA    + G ++  +  L 
Sbjct: 107 DVWLNIAHIYVEQRQFVAAVQMYENALKKFSRNHNVEVMVYLARAYYKCGKLQDCKTTLL 286

Query: 446 TASSLAPHMYEPHFNFATVSDKIG 469
            A  +APH     +N A V  K+ 
Sbjct: 287 KARHVAPHDTVLLYNIALVQQKLA 358
>18279
          Length = 706

 Score = 33.5 bits (75), Expect = 0.18,   Method: Compositional matrix adjust.
 Identities = 26/84 (30%), Positives = 36/84 (42%), Gaps = 2/84 (2%)
 Frame = +3

Query: 388 DVWYNLGHIAVGIGDTNLAHQCFRLAL--VHNNHHAEAYNNLAVLEMRKGHVEQARALLQ 445
           DVW N+ HI V       A Q +  AL     NH+ E    LA    + G ++  +  L 
Sbjct: 417 DVWLNIAHIYVEQRQFVAAVQMYENALKKFSRNHNVEVMVYLARAYYKCGKLQDCKTTLL 596

Query: 446 TASSLAPHMYEPHFNFATVSDKIG 469
            A  +APH     +N A V  K+ 
Sbjct: 597 KARHVAPHDTVLLYNIALVQQKLA 668
>28154
          Length = 374

 Score = 33.1 bits (74), Expect = 0.26,   Method: Compositional matrix adjust.
 Identities = 24/88 (27%), Positives = 34/88 (38%)
 Frame = +1

Query: 388 DVWYNLGHIAVGIGDTNLAHQCFRLALVHNNHHAEAYNNLAVLEMRKGHVEQARALLQTA 447
           DV  NLG +    G+ N A  CF+ AL      A  +N L       G  E+A      A
Sbjct: 97  DVQCNLGVLFNLSGEYNKAVDCFQAALQARPKDALLWNKLGATLANGGRSEEAVDAYHNA 276

Query: 448 SSLAPHMYEPHFNFATVSDKIGDLQRSY 475
             L+P      +N       +G + R +
Sbjct: 277 LQLSPGFIRSRYNLGIACINLGCIGRPW 360
>27876
          Length = 453

 Score = 32.0 bits (71), Expect = 0.54,   Method: Composition-based stats.
 Identities = 15/27 (55%), Positives = 19/27 (70%)
 Frame = -1

Query: 145 SGRFVRLGTASMLTSPDGPFINLSRLN 171
           SGRF+ L T+S L   D  F+N+SRLN
Sbjct: 237 SGRFIPLVTSSRLLGLDAVFLNVSRLN 157
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|21312520|ref|NP_077198.1| quinoid dihydropteridine
reductase [Mus musculus]
         (241 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

15136                                                                  33   0.095
34336                                                                  32   0.26 
>15136
          Length = 393

 Score = 33.1 bits (74), Expect = 0.095,   Method: Compositional matrix adjust.
 Identities = 14/23 (60%), Positives = 17/23 (73%)
 Frame = +2

Query: 216 NKRPNSGSLIQVVTTDGKTELTP 238
            +RP SGSLIQ++T D  TEL P
Sbjct: 2   EERPASGSLIQLITKDSVTELVP 70
>34336
          Length = 779

 Score = 32.0 bits (71), Expect = 0.26,   Method: Compositional matrix adjust.
 Identities = 15/46 (32%), Positives = 26/46 (56%), Gaps = 4/46 (8%)
 Frame = +3

Query: 143 GMIGYGMAKG----AVHQLCQSLAGKNSGMPPGAAAIAVLPVTLDT 184
           G +G+G+A+G     +HQLC+ L  + SG P    ++  +P+ L  
Sbjct: 411 GPVGHGLAQGEARRVLHQLCRRLQRRGSGGPDHHRSLPQVPLPLQP 548
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|134053905|ref|NP_848731.2| proteasome 26S non-ATPase
subunit 11 [Mus musculus]
         (422 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

31650                                                                  34   0.097
>31650
          Length = 365

 Score = 34.3 bits (77), Expect = 0.097,   Method: Compositional matrix adjust.
 Identities = 20/64 (31%), Positives = 38/64 (59%)
 Frame = -1

Query: 4   AAVVEFQRAQSLLSTDREASIDILHSIVKRDIQENDEEAVQVKEQSILELGSLLAKTGQA 63
           A V   Q+A  +  T+   + ++L  IVK++++  D++A++VKEQ+ILE+   L +   +
Sbjct: 209 ATVEVLQQAFDMRKTNSVHASELLTKIVKQEVRTLDDDAIRVKEQAILEIRQYLCRNKSS 30

Query: 64  AELG 67
              G
Sbjct: 29  NRAG 18
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|87044901|ref|NP_848472.2| tubulin-specific chaperone
c [Mus musculus]
         (341 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

27430                                                                  34   0.11 
21808                                                                  32   0.43 
>27430
          Length = 636

 Score = 33.9 bits (76), Expect = 0.11,   Method: Compositional matrix adjust.
 Identities = 27/97 (27%), Positives = 37/97 (38%), Gaps = 17/97 (17%)
 Frame = +1

Query: 168 EEEGAPGASWACGFSNLESQDLEKRAEELHQR-----------DVLLSD------LTNCT 210
           +E  AP        S+L++  L  R   L  R            VL +       LTNCT
Sbjct: 4   QEGKAPNGPNPSSLSSLDNASLPPRKRVLKHRADSTPFPAPVQKVLSAGVQDSVLLTNCT 183

Query: 211 VKLCGNPNTLRLAKARGCKVLCGPVTTSVFLEDCRDC 247
           V     P +  +A   G  V+  PVT +  L  C+ C
Sbjct: 184 VNHLQLPKSSSVATTSGASVVVMPVTVTATLVSCKQC 294
>21808
          Length = 1011

 Score = 31.6 bits (70), Expect = 0.43,   Method: Compositional matrix adjust.
 Identities = 19/40 (47%), Positives = 26/40 (65%)
 Frame = +1

Query: 174 GASWACGFSNLESQDLEKRAEELHQRDVLLSDLTNCTVKL 213
           GA  ACG + LESQ+   R  +L  R++L+SD  N TVK+
Sbjct: 253 GAQIACGMAYLESQNYIHR--DLAARNILVSD--NNTVKI 360
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|33239421|ref|NP_082751.1| Nice-4 protein homolog
isoform 1 [Mus musculus]
         (1105 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

19613                                                                  35   0.12 
04941                                                                  35   0.14 
07878                                                                  32   1.8  
34350                                                                  30   6.3  
>19613
          Length = 803

 Score = 35.4 bits (80), Expect = 0.12,   Method: Compositional matrix adjust.
 Identities = 39/106 (36%), Positives = 56/106 (52%), Gaps = 6/106 (5%)
 Frame = +2

Query: 933  YYTG--VPGLPSTFQYG--PAVFPVAPTSSKQHGVNVSVNASATPFQQPSGYGSH-GYNT 987
            YY G  +PG  + FQY    A+ PV  T++  H     V  + T  Q P  YGSH G+ +
Sbjct: 512  YYPGAMLPGA-AGFQYPMFSAMPPVTNTAAAAH-----VPGTTTAAQLPKTYGSHQGFPS 673

Query: 988  GVSVTSSNTGVPDISGSVYSKTQ-QSFEKQGFHSGTPAASFNLPSA 1032
              + T++     D++   Y K+  Q F+KQGF +GTP   F+LP A
Sbjct: 674  KGTGTTA-----DMTSGAYGKSHAQGFDKQGFPAGTP-PPFSLPLA 793
>04941
          Length = 1426

 Score = 35.4 bits (80), Expect = 0.14,   Method: Compositional matrix adjust.
 Identities = 21/67 (31%), Positives = 30/67 (44%), Gaps = 12/67 (17%)
 Frame = -3

Query: 257 WRTATEEWGTEDWNEDLSETKIFTAS------------NVSSVPLPAENVTITAGQRIDL 304
           W  ++E+W  + W   L +TK+FT S            NVS  P        T GQR+D+
Sbjct: 971 WGESSEDWCEDQWTGSLEDTKVFTPSQAKPSVEADMSTNVSDSP-------NTLGQRLDV 813

Query: 305 AVLLGKT 311
             L  K+
Sbjct: 812 GSLFSKS 792
>07878
          Length = 1340

 Score = 31.6 bits (70), Expect = 1.8,   Method: Compositional matrix adjust.
 Identities = 18/42 (42%), Positives = 26/42 (61%), Gaps = 4/42 (9%)
 Frame = +3

Query: 1000 DISGSVYSKTQ----QSFEKQGFHSGTPAASFNLPSALGSGG 1037
            D++ S+Y K      +S+EKQ FHSGTP   FN+ +   +GG
Sbjct: 9    DLTSSMYGKGHVALNKSYEKQSFHSGTPPP-FNMANTQTAGG 131
>34350
          Length = 483

 Score = 29.6 bits (65), Expect = 6.3,   Method: Compositional matrix adjust.
 Identities = 15/34 (44%), Positives = 18/34 (52%)
 Frame = +1

Query: 950 VFPVAPTSSKQHGVNVSVNASATPFQQPSGYGSH 983
           V+ V PTS+  HGVN   N   T F     YGS+
Sbjct: 13  VYGVCPTSNSNHGVN---NVKRTEFDNEEDYGSY 105
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|21624609|ref|NP_080788.1| biphenyl hydrolase-like
(serine hydrolase, breast epithelial mucin-associated antigen) [Mus
musculus]
         (291 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

03845                                                                  33   0.13 
13372                                                                  33   0.17 
09813                                                                  28   4.5  
>03845
          Length = 1326

 Score = 33.1 bits (74), Expect = 0.13,   Method: Compositional matrix adjust.
 Identities = 23/76 (30%), Positives = 38/76 (50%), Gaps = 10/76 (13%)
 Frame = +2

Query: 226 RHLLPLVQCPTLIVHGEKDPLVPRFHADFLLQHVKGSR--------LHLMPEGKHNLHLR 277
           +HL+  V+CPTL++H E D +VP      L Q V  ++        +H+ P  K   H R
Sbjct: 698 QHLIH-VRCPTLMLHAEDDKIVPIDLGKKLFQSVVSAKKTDQAKITMHVFPADKGYGHNR 874

Query: 278 F--ADEFNRLVEDFLQ 291
              A +   +++ F+Q
Sbjct: 875 VNQAPDLGSVIKQFVQ 922
>13372
          Length = 468

 Score = 32.7 bits (73), Expect = 0.17,   Method: Compositional matrix adjust.
 Identities = 21/70 (30%), Positives = 34/70 (48%), Gaps = 10/70 (14%)
 Frame = +1

Query: 232 VQCPTLIVHGEKDPLVPRFHADFLLQHVKGSR--------LHLMPEGKHNLHLRF--ADE 281
           V+CPTL++H E D +VP      L Q V  ++        +H+ P  K   H R   A +
Sbjct: 226 VRCPTLMLHAEDDKIVPIDLGKKLFQSVVSAKKTDQAKITMHVFPADKGYGHNRVNQAPD 405

Query: 282 FNRLVEDFLQ 291
              +++ F+Q
Sbjct: 406 LGSVIKQFVQ 435
>09813
          Length = 765

 Score = 28.1 bits (61), Expect = 4.5,   Method: Compositional matrix adjust.
 Identities = 14/42 (33%), Positives = 23/42 (54%)
 Frame = -2

Query: 120 DAVDLMKALQFKQVSLLGWSDGGITALIAAAKYPSYIRKMVI 161
           D   L+  L +K+  L+G   GG+ A   A  YP  ++++VI
Sbjct: 740 DLRQLIATLGYKKCVLVGHDWGGLVAWALAQNYPDLVQQLVI 615
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|131888529|ref|NP_062312.3| gamma-aminobutyric acid
(GABA-B) receptor, 1 [Mus musculus]
         (960 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

03995                                                                  35   0.15 
05037                                                                  33   0.76 
11017                                                                  29   9.4  
>03995
          Length = 944

 Score = 35.0 bits (79), Expect = 0.15,   Method: Compositional matrix adjust.
 Identities = 31/96 (32%), Positives = 41/96 (42%), Gaps = 6/96 (6%)
 Frame = -1

Query: 62  IEYVCRGEREVVGPKVRKCLANGSWTDMDTPSRCVRICSKSYLTLENGKVFLTGGDLPAL 121
             Y CR    + GP  R C +NG+WT  + P+   + C K +  + NG V          
Sbjct: 743 CSYRCRRGFTLTGPAYRTCQSNGTWTGSE-PTCTPKTCGKLHPPV-NGFVK----PASCQ 582

Query: 122 DGA-----RVDFRCDPDFHLVGSSRSICSQGQ-WST 151
           DGA     R  FRC+  F   G   + C   Q WST
Sbjct: 581 DGAVPFKTRCKFRCNKGFRRRGKPGAKCLANQRWST 474

 Score = 29.6 bits (65), Expect = 6.7,   Method: Compositional matrix adjust.
 Identities = 20/75 (26%), Positives = 29/75 (38%)
 Frame = -1

Query: 22  PNVTSEGCQIIHPPWEGGIRYRGLTRDQVKAINFLPVDYEIEYVCRGEREVVGPKVRKCL 81
           P  T + C  +HPP  G ++        V      P     ++ C       G    KCL
Sbjct: 656 PTCTPKTCGKLHPPVNGFVKPASCQDGAV------PFKTRCKFRCNKGFRRRGKPGAKCL 495

Query: 82  ANGSWTDMDTPSRCV 96
           AN  W+   + +RCV
Sbjct: 494 ANQRWSTDGSLTRCV 450
>05037
          Length = 723

 Score = 32.7 bits (73), Expect = 0.76,   Method: Compositional matrix adjust.
 Identities = 28/86 (32%), Positives = 38/86 (44%), Gaps = 6/86 (6%)
 Frame = -1

Query: 72  VVGPKVRKCLANGSWTDMDTPSRCVRICSKSYLTLENGKVFLTGGDLPALDGA-----RV 126
           + GP  R C +NG+WT  + P+   + C K +  + NG V          DGA     R 
Sbjct: 723 LTGPAYRTCQSNGTWTGSE-PTCTPKTCGKLHPPV-NGFV----KPASCQDGAVPFKTRC 562

Query: 127 DFRCDPDFHLVGSSRSICSQGQ-WST 151
            FRC+  F   G   + C   Q WST
Sbjct: 561 KFRCNKGFRRRGKPGAKCLANQRWST 484

 Score = 30.4 bits (67), Expect = 4.0,   Method: Compositional matrix adjust.
 Identities = 20/75 (26%), Positives = 29/75 (38%)
 Frame = -1

Query: 22  PNVTSEGCQIIHPPWEGGIRYRGLTRDQVKAINFLPVDYEIEYVCRGEREVVGPKVRKCL 81
           P  T + C  +HPP  G ++        V      P     ++ C       G    KCL
Sbjct: 666 PTCTPKTCGKLHPPVNGFVKPASCQDGAV------PFKTRCKFRCNKGFRRRGKPGAKCL 505

Query: 82  ANGSWTDMDTPSRCV 96
           AN  W+   + +RCV
Sbjct: 504 ANQRWSTDGSLTRCV 460
>11017
          Length = 928

 Score = 28.9 bits (63), Expect = 9.4,   Method: Composition-based stats.
 Identities = 14/37 (37%), Positives = 22/37 (59%)
 Frame = +3

Query: 70  REVVGPKVRKCLANGSWTDMDTPSRCVRICSKSYLTL 106
           R +VG   R+ +  G+   M T   CVR+CSK+Y+ +
Sbjct: 288 RRIVGVGQRRRIPGGTQVCMRT-XVCVRVCSKTYIIV 395
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|28893421|ref|NP_796284.1| X-prolyl aminopeptidase
(aminopeptidase P) 3, putative [Mus musculus]
         (386 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

07841                                                                  33   0.15 
20261                                                                  32   0.40 
>07841
          Length = 643

 Score = 33.5 bits (75), Expect = 0.15,   Method: Compositional matrix adjust.
 Identities = 26/102 (25%), Positives = 46/102 (45%), Gaps = 6/102 (5%)
 Frame = -1

Query: 195 LRAETNMVWYDWMKPSHAQLHSDYMQP--LTEAKARSKNKVRSVQQLIQRLRLVKSPSEI 252
           L + TNMV  D+    H  L+ D   P  L E +     K++S+Q     +  +   +E+
Sbjct: 493 LLSNTNMV--DFAMDVHKNLYPDQRDPANLREKRQEVVGKLKSLQAETDIITKIFEETEV 320

Query: 253 KRMQIAGKLTSEAFIETMFAS----KAPIDEAFLYAKFEFEC 290
           +R QI          + ++      +  +D  + YAKF++EC
Sbjct: 319 QR-QIQSSRDGRQLFDFLYKEYGFKQQMLDTLYKYAKFQYEC 197
>20261
          Length = 1036

 Score = 32.0 bits (71), Expect = 0.40,   Method: Compositional matrix adjust.
 Identities = 20/60 (33%), Positives = 28/60 (46%)
 Frame = +3

Query: 39  KKIPNRYLGQPSPVTHPHLLRPGEVTPGLSQVEYALRRHKLMALVHKEAQGHSGTDHTVV 98
           K    R LGQ     +P LL  G++TP    +E AL   +L    +K A+  S    TV+
Sbjct: 84  KTAVRRSLGQEETECYPLLLLYGKITPAFFNIEQALYSSRLF---NKSAEICSAEKITVI 254
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|42734471|ref|NP_705828.2| tetratricopeptide repeat
domain 26 [Mus musculus]
         (554 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

24872                                                                  34   0.15 
25402                                                                  30   2.8  
02218                                                                  29   4.5  
32766                                                                  28   8.4  
>24872
          Length = 521

 Score = 34.3 bits (77), Expect = 0.15,   Method: Composition-based stats.
 Identities = 13/23 (56%), Positives = 18/23 (78%)
 Frame = -1

Query: 368 CFFLLKQFDDVLIYLNSFKSYFY 390
           CF+L + F  VLIY NSF+++FY
Sbjct: 494 CFYLFRTFSTVLIYKNSFEAFFY 426
>25402
          Length = 1275

 Score = 30.0 bits (66), Expect = 2.8,   Method: Compositional matrix adjust.
 Identities = 21/55 (38%), Positives = 29/55 (52%)
 Frame = -1

Query: 416 FLLIQSEKLKNDYIYLSWLARCYIMNKKPRLAWELYLKMETSGESFSLLQLIAND 470
           FLL+ S    NDY+ LS+L R + ++    LAW L+         FS L L+A D
Sbjct: 468 FLLVVSLCGHNDYLLLSFLGRAFQLSGFG-LAWYLH--------PFSYLALVARD 331
>02218
          Length = 2895

 Score = 29.3 bits (64), Expect = 4.5,   Method: Compositional matrix adjust.
 Identities = 14/36 (38%), Positives = 21/36 (58%)
 Frame = -2

Query: 113  AGFKAPKSRLQNRLLFHLAHKFNDEKKLMNFHQNLQ 148
            AG K PK+   + +L   +   NDE +L NFH++L 
Sbjct: 1073 AGAKLPKNIEPSNMLLTNSCPLNDENRLANFHEDLS 966
>32766
          Length = 720

 Score = 28.1 bits (61), Expect = 8.4,   Method: Compositional matrix adjust.
 Identities = 11/20 (55%), Positives = 17/20 (85%)
 Frame = -2

Query: 370 FLLKQFDDVLIYLNSFKSYF 389
           FL +QF  V++Y+++FKSYF
Sbjct: 119 FLTRQFSCVVVYVSNFKSYF 60
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6678347|ref|NP_033408.1| thymus cell antigen 1, theta
[Mus musculus]
         (162 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

13135                                                                  32   0.15 
05965                                                                  26   6.9  
>13135
          Length = 849

 Score = 31.6 bits (70), Expect = 0.15,   Method: Compositional matrix adjust.
 Identities = 20/85 (23%), Positives = 40/85 (47%), Gaps = 1/85 (1%)
 Frame = -1

Query: 30  VNQNLRLDCRHENNTKDNSIQHEFSLTREKRKHVLSGTLGIPEH-TYRSRVTLSNQPYIK 88
           +N++++L C  EN   D  +Q   ++ R      +  ++    +  ++  + L + P   
Sbjct: 675 INKDVQLXCVVENKPIDKEVQWVGTVVRNGTTRTIPVSIATRSYDPFKYSIDLPS-PTSW 499

Query: 89  VLTLANFTTKDEGDYFCELQVSGAN 113
            L + N    DEG Y C++Q+S  N
Sbjct: 498 RLRIQNGQVTDEGVYTCQVQLSNQN 424
>05965
          Length = 1350

 Score = 26.2 bits (56), Expect = 6.9,   Method: Compositional matrix adjust.
 Identities = 14/50 (28%), Positives = 23/50 (46%), Gaps = 1/50 (2%)
 Frame = +2

Query: 86  YIKVLTLAN-FTTKDEGDYFCELQVSGANPMSSNKSISVYRDKLVKCGGI 134
           Y ++  + N F  + E   FC  +  GAN   +  S+   RDK  +C  +
Sbjct: 206 YYQINYIVNCFRHRGESKNFCHARFCGANYSQATSSLKKKRDKKSECRNV 355
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|21450213|ref|NP_659078.1| alanyl-tRNA synthetase
domain containing 1 [Mus musculus]
         (412 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

19334                                                                  33   0.16 
>19334
          Length = 923

 Score = 33.5 bits (75), Expect = 0.16,   Method: Compositional matrix adjust.
 Identities = 29/90 (32%), Positives = 39/90 (43%), Gaps = 11/90 (12%)
 Frame = -1

Query: 154 IEQSVNQKIRDRLPVSVRELS----LDDPEVEQVRG----RGLPDDHAGPIRVVTIEGVD 205
           + Q   QKI D   VS   +S     D   V  VRG     GL D H G +  V      
Sbjct: 347 VRQMHGQKITDLSIVSKIAISCCYFFDSFSVLSVRGDDGLEGLFDKHGGVVVHVLYRHHH 168

Query: 206 SNMCC---GTHVSNLSDLQVIKILGTEKGK 232
            NMCC      + NL++  V+ +L + KG+
Sbjct: 167 HNMCCVGLRVQIHNLNNHSVLILLLSVKGR 78
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31542131|ref|NP_075699.2| acidic (leucine-rich)
nuclear phosphoprotein 32 family, member E [Mus musculus]
         (260 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

30747                                                                  33   0.16 
08106                                                                  32   0.28 
37214                                                                  32   0.38 
14078                                                                  30   0.88 
17298                                                                  29   2.1  
17623                                                                  28   3.3  
23232                                                                  27   6.1  
>30747
          Length = 1168

 Score = 32.7 bits (73), Expect = 0.16,   Method: Compositional matrix adjust.
 Identities = 37/119 (31%), Positives = 52/119 (43%), Gaps = 23/119 (19%)
 Frame = +3

Query: 33  EIEGLND--TFKELEFLSMANVELSSLARLPSLNKLRKLELSDNIISG--GLEVLAEKCP 88
           EI  + D   F++L  L ++   ++ +  L     LR L+L DN +S   GLE L E C 
Sbjct: 228 EITAVPDLEKFRKLRVLDVSGNYITKIQHLEFTQDLRDLKLYDNKVSQVQGLESLKELCS 407

Query: 89  -------------------NLTYLNLSGNKIKDLSTVEALQNLKNLKSLDLFNCEITNL 128
                               L  L L  N++  L T E L  + N+ +LDL N  ITNL
Sbjct: 408 LQLQYNQIESLGKGLNALKKLKCLRLDSNRLTKLDTNELLSCV-NISTLDLSNNHITNL 581
>08106
          Length = 997

 Score = 32.0 bits (71), Expect = 0.28,   Method: Compositional matrix adjust.
 Identities = 24/81 (29%), Positives = 40/81 (49%)
 Frame = +2

Query: 66  LRKLELSDNIISGGLEVLAEKCPNLTYLNLSGNKIKDLSTVEALQNLKNLKSLDLFNCEI 125
           L  L L DN +   L+   E+   L Y+N+ GN +  +     L++L  L++L L    +
Sbjct: 50  LATLHLRDNQLEN-LDGFTEELKELQYVNVRGNLLTSIKEAAKLKDLPLLRALSLAENPV 226

Query: 126 TNLEDYRESIFELLQQITYLD 146
            + +DYR  I   L+ +  LD
Sbjct: 227 ADEDDYRLEILIALRCLERLD 289
>37214
          Length = 316

 Score = 31.6 bits (70), Expect = 0.38,   Method: Compositional matrix adjust.
 Identities = 18/41 (43%), Positives = 26/41 (63%)
 Frame = -2

Query: 60  LPSLNKLRKLELSDNIISGGLEVLAEKCPNLTYLNLSGNKI 100
           L + + L  L+LSDN IS   E + +   NL++L+LSGN I
Sbjct: 123 LHAFSNLSTLQLSDNKISSIPEGVFDSLHNLSHLDLSGNPI 1
>14078
          Length = 1045

 Score = 30.0 bits (66), Expect = 0.88,   Method: Compositional matrix adjust.
 Identities = 23/81 (28%), Positives = 39/81 (48%)
 Frame = -1

Query: 66  LRKLELSDNIISGGLEVLAEKCPNLTYLNLSGNKIKDLSTVEALQNLKNLKSLDLFNCEI 125
           L  L L DN +   L+   +    L Y+NL GN +  +  +  L+ L  L++L L    +
Sbjct: 295 LTTLHLRDNQLES-LDGFTDDLKELQYVNLRGNLMSSVKEMTKLKCLSFLRALALSENPV 119

Query: 126 TNLEDYRESIFELLQQITYLD 146
            + +DYR  +   L+ +  LD
Sbjct: 118 ADEDDYRMEVLIALRTLERLD 56
>17298
          Length = 476

 Score = 28.9 bits (63), Expect = 2.1,   Method: Compositional matrix adjust.
 Identities = 23/45 (51%), Positives = 24/45 (53%)
 Frame = +3

Query: 58  ARLPSLNKLRKLELSDNIISGGLEVLAEKCPNLTYLNLSGNKIKD 102
           A L SL  L  L L+DN I      L E C  L  L LSGNKIKD
Sbjct: 288 ADLSSLPHLNCLNLADNQIEELPNELCE-CTRLKELKLSGNKIKD 419
>17623
          Length = 687

 Score = 28.1 bits (61), Expect = 3.3,   Method: Compositional matrix adjust.
 Identities = 22/79 (27%), Positives = 36/79 (45%), Gaps = 6/79 (7%)
 Frame = +1

Query: 74  NIISGGLEVLA-EKCPNLTYLNLSGNKIKDLSTVEALQNLKNLKSLDLFNCEITNLEDYR 132
           N+ SG   ++     PN+  + + G  I  LS    L  L NLK L +  C+I  +E   
Sbjct: 16  NVFSGFPRLIGLHHFPNIHTMTIIGQSIPTLS---GLNTLTNLKELWVAECQIKKIEGLE 186

Query: 133 -----ESIFELLQQITYLD 146
                E ++    QI+++D
Sbjct: 187 KCVLVEKLYLYGNQISHID 243
>23232
          Length = 478

 Score = 27.3 bits (59), Expect = 6.1,   Method: Compositional matrix adjust.
 Identities = 15/38 (39%), Positives = 21/38 (55%)
 Frame = +2

Query: 38  NDTFKELEFLSMANVELSSLARLPSLNKLRKLELSDNI 75
           N T  ++ FLS A+    S  RLP+LN  R+   S N+
Sbjct: 119 NKTSNQIMFLSPADRYGKSQGRLPTLNLTRRSSRSKNL 232
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|70778826|ref|NP_775619.2| valosin-containing protein
(p97)/p47 complex-interacting protein p135 [Mus musculus]
         (1220 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

08158                                                                  35   0.17 
35237                                                                  30   7.6  
22017                                                                  30   7.9  
>08158
          Length = 1019

 Score = 35.0 bits (79), Expect = 0.17,   Method: Composition-based stats.
 Identities = 26/87 (29%), Positives = 42/87 (48%)
 Frame = -3

Query: 240 NLKQHFQQHLARYQALFHDFIDAAEWEDIINECDPLFVPPEGVPLGLRNIHIFGLANVLH 299
           N  +  Q H +  Q   H F++ +   +II++C P  +    +P  + +I     +N+L 
Sbjct: 768 NRGESSQPHSSEEQTFPHSFLNFSVVREIISKCFPTTIVKNPLPQFVGDILSNKKSNLLG 589

Query: 300 RPIILLDSLSGMRSSGDYSATFLPGLI 326
              IL DSL     +  Y+AT LP LI
Sbjct: 588 NS-ILSDSLVASLDANAYTATILPQLI 511
>35237
          Length = 678

 Score = 29.6 bits (65), Expect = 7.6,   Method: Composition-based stats.
 Identities = 14/48 (29%), Positives = 23/48 (47%), Gaps = 2/48 (4%)
 Frame = -2

Query: 309 SGMRSSGDYSATFLPGLIPAEKCTGRDGHLNKPI--CIAWSSSGRNHY 354
           +G+ S G +   +L    P   C G +   N  +  C+ W+S GR H+
Sbjct: 167 AGVLSPGGWPHDYLKPRAPRVTCFGAETRKNGSVLGCMGWASCGRGHW 24
>22017
          Length = 531

 Score = 29.6 bits (65), Expect = 7.9,   Method: Compositional matrix adjust.
 Identities = 10/24 (41%), Positives = 15/24 (62%)
 Frame = +1

Query: 249 LARYQALFHDFIDAAEWEDIINEC 272
           +A Y A+ H F+ A+ WED +  C
Sbjct: 457 IAPYPAVLHSFVAASRWEDAVRLC 528
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|82887622|ref|XP_926806.1| PREDICTED: similar to
Protein KIAA1219 isoform 12 [Mus musculus]
         (1495 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

21576                                                                  35   0.17 
03818                                                                  32   1.8  
07509                                                                  32   2.7  
00763                                                                  31   4.5  
>21576
          Length = 723

 Score = 35.4 bits (80), Expect = 0.17,   Method: Compositional matrix adjust.
 Identities = 15/27 (55%), Positives = 21/27 (77%)
 Frame = -2

Query: 1028 FPEEVDKIPFVKADLSIPDLHEIVTEE 1054
            FP  +DK+PF  A LSIP+L E+++EE
Sbjct: 479  FPSALDKLPFSPAALSIPELMELLSEE 399
>03818
          Length = 1415

 Score = 32.0 bits (71), Expect = 1.8,   Method: Composition-based stats.
 Identities = 15/26 (57%), Positives = 18/26 (69%)
 Frame = +2

Query: 934 YSRLPTINKHSFRYFVLDNSVILAML 959
           YS + TIN  SF YF+L N+ IL ML
Sbjct: 260 YSDITTINNFSFIYFLLKNTDILIML 337
>07509
          Length = 646

 Score = 31.6 bits (70), Expect = 2.7,   Method: Compositional matrix adjust.
 Identities = 25/69 (36%), Positives = 30/69 (43%)
 Frame = -3

Query: 1327 KKLPQGRPVPPLGPETRVSVVWVERYDDIENFPLSDLMTEISTGVETTANSSTSLRSTTL 1386
            KK+P  R V  LG ET  S      +D   NFP S L +E +  VET     T  +    
Sbjct: 371  KKIPTSR*VMSLGMETTTSSF----HDSSINFPTSKL*SEFTRRVETEEKLKTEGKKNHE 204

Query: 1387 EKEVPVIFI 1395
             K V   FI
Sbjct: 203  XKSVRQFFI 177
>00763
          Length = 2291

 Score = 30.8 bits (68), Expect = 4.5,   Method: Compositional matrix adjust.
 Identities = 21/60 (35%), Positives = 26/60 (43%)
 Frame = +1

Query: 1337 PLGPETRVSVVWVERYDDIENFPLSDLMTEISTGVETTANSSTSLRSTTLEKEVPVIFIH 1396
            P G ET  S      +D   NFP S L +E +  VET     T     + +KE   IF H
Sbjct: 316  PFGMETTTSSF----HDSSTNFPTSKL*SEFTRRVETEEKLKTEGEKKSRDKERXTIFYH 483
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|170650647|ref|NP_032513.3| rho/rac guanine nucleotide
exchange factor (GEF) 2 [Mus musculus]
         (985 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

11641                                                                  35   0.19 
35187                                                                  35   0.22 
38272                                                                  33   0.69 
09308                                                                  32   1.5  
01565                                                                  31   2.3  
30964                                                                  30   6.2  
>11641
          Length = 2509

 Score = 34.7 bits (78), Expect = 0.19,   Method: Compositional matrix adjust.
 Identities = 28/117 (23%), Positives = 58/117 (49%), Gaps = 3/117 (2%)
 Frame = -1

Query: 336  RKTYSEFCSRHTKALKL---YKELYARDKRFQQFIRKMTRSAVLKRHGVQECILLVTQRI 392
            + TY+ +C  H   + +   Y EL    + F   + +M R   +    V+  ++   QRI
Sbjct: 2509 KNTYAPYCRHHDDVISVMDKYHELPEACQYFAAKVEEMRRRTNI--FDVEAMLIKPVQRI 2336

Query: 393  TKYPVLINRILQNSHGVEEEYQDLASALGLVKELLSNVDQDVHELEKEARLQEIYNR 449
             KYP+L+N + +++   E+++ D  +A+G     +++V   ++E ++   L   Y R
Sbjct: 2335 LKYPLLLNELFKST---EDDHPD-KTAIGNAIRAMTDVATAINEYKRRKDLVFKYKR 2177
>35187
          Length = 593

 Score = 34.7 bits (78), Expect = 0.22,   Method: Composition-based stats.
 Identities = 15/57 (26%), Positives = 28/57 (49%), Gaps = 3/57 (5%)
 Frame = -3

Query: 36  YTNGHLFTTISVSGMTMCYACNKSITAKEAL--ICPTCNVTIHNRCKDTLAN-CTKV 89
           + +GH FT  +    T C+ C   +     +  +C  CN  +H+RC  T+ + C+ +
Sbjct: 327 HGHGHFFTKKTFHKPTYCHHCTDILWGLIGVGYVCEVCNFVVHDRCMKTVVSPCSSI 157
>38272
          Length = 749

 Score = 32.7 bits (73), Expect = 0.69,   Method: Composition-based stats.
 Identities = 28/95 (29%), Positives = 45/95 (47%), Gaps = 2/95 (2%)
 Frame = +2

Query: 339 YSEFCSRHTKALKLYKELYARDKRFQQFIRKMTRSAVLKRHGVQECILLVTQRITKYPVL 398
           Y  FCS    +  +  E Y   + F Q  +K+       R+ +   I+   QRITKY +L
Sbjct: 11  YYYFCSNKPLSEFIVNEHY---QYFDQIRQKLGH-----RNDLSALIITPVQRITKYVLL 166

Query: 399 INRILQNSH--GVEEEYQDLASALGLVKELLSNVD 431
           IN IL+ +   G+  E   L  A   +K+++  V+
Sbjct: 167 INEILRETKRAGLHNEVATLMEAGEQMKDVVKKVN 271
>09308
          Length = 1095

 Score = 31.6 bits (70), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 15/41 (36%), Positives = 21/41 (51%)
 Frame = -2

Query: 173 QSTDSLNMRNRTLSVESLIDEGVEVFYNELMSDFEMDEKDF 213
           Q+ DSLNM   +LSV   +  G    YN L S++ +    F
Sbjct: 599 QNHDSLNMLKSSLSVPKSVQSGALCIYNSLCSNYIVQNGHF 477
>01565
          Length = 485

 Score = 31.2 bits (69), Expect = 2.3,   Method: Composition-based stats.
 Identities = 33/114 (28%), Positives = 52/114 (45%), Gaps = 10/114 (8%)
 Frame = -1

Query: 152 TTNIAGHFNDESPLGLRQILSQSTDSLNMRNRTLSVESLIDEGVEVFYNELMSDFEMDEK 211
           T+N  G+ N E+PL L    S+    LNM   + SV+  +  G    YN L S+  +  +
Sbjct: 338 TSNRHGN*NTENPLKLWA--SKVMIPLNMLKSSFSVKKYVQSGALCMYNSLCSN*IVQNR 165

Query: 212 DF-----EADSWSLAVDSS--FLQQ-HKKEVMK--KQDVIYELIQTELHHVRTL 255
            F     ++ S  L + SS   L+  H   ++K   +   Y  I + LH +R L
Sbjct: 164 HFLDCKHQSSSIGLGIFSSENLLKS*HFPRLIKV*NKSSQYNFIYSALHCLRRL 3
>30964
          Length = 894

 Score = 29.6 bits (65), Expect = 6.2,   Method: Composition-based stats.
 Identities = 16/47 (34%), Positives = 25/47 (53%)
 Frame = -1

Query: 660 LREVEGLKDLLLGPCVDLPMTSREPALPLDSDSGSCPGVTANGEART 706
           L+EVE +   L    ++ PMT  +   P+ + + S P   A G+ART
Sbjct: 588 LKEVEKIYQELKSKGIEFPMTDLDNMAPIHTPARSVPFNLAAGDART 448
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|22122803|ref|NP_666346.1| membrane magnesium
transporter 1 [Mus musculus]
         (131 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

08776                                                                  30   0.19 
29178                                                                  27   3.0  
11360                                                                  25   7.8  
>08776
          Length = 944

 Score = 30.4 bits (67), Expect = 0.19,   Method: Compositional matrix adjust.
 Identities = 18/42 (42%), Positives = 24/42 (57%), Gaps = 1/42 (2%)
 Frame = +3

Query: 51  LAFAVTCYGIVHIAGEFKDMDATSELK-NKTFDTLRNHPSFY 91
           L FAV C+ IVH+   FK M     L+ ++TF TL+  P  Y
Sbjct: 750 LVFAVRCHVIVHL--RFKKMWFFRSLELDRTFLTLKKSPGMY 869
>29178
          Length = 867

 Score = 26.6 bits (57), Expect = 3.0,   Method: Compositional matrix adjust.
 Identities = 13/30 (43%), Positives = 20/30 (66%)
 Frame = +3

Query: 97  GRVLFRPSDATNSSNLDALSSNTSLKLRKF 126
           GRVLFR +  T+S+ LD+  +  SL ++K 
Sbjct: 312 GRVLFRNTINTSSAGLDSQQNK*SLTIKKL 401
>11360
          Length = 514

 Score = 25.4 bits (54), Expect = 7.8,   Method: Compositional matrix adjust.
 Identities = 13/40 (32%), Positives = 21/40 (52%), Gaps = 4/40 (10%)
 Frame = -2

Query: 35  EKEDESLPIDIVLQTL----LAFAVTCYGIVHIAGEFKDM 70
           +K + S+    +L+T+    LAF  TCY   H +G  + M
Sbjct: 144 QKRENSIAFSYLLRTVPLLTLAFTYTCYEQTHTSGTPQIM 25
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|124378050|ref|NP_694765.2| SEC16 homolog A [Mus
musculus]
         (2357 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

18183                                                                  36   0.20 
14762                                                                  32   4.4  
>18183
          Length = 414

 Score = 35.8 bits (81), Expect = 0.20,   Method: Compositional matrix adjust.
 Identities = 17/34 (50%), Positives = 21/34 (61%)
 Frame = +1

Query: 2129 FSRWLPGKKRTEAYLPDDKNKSIVWDEKKNQWVN 2162
            FSR+   + + E  LPDDKN  IVWD    +WVN
Sbjct: 127  FSRF--SRNKNEMKLPDDKNPPIVWDSVNKRWVN 222
>14762
          Length = 1307

 Score = 31.6 bits (70), Expect = 4.4,   Method: Compositional matrix adjust.
 Identities = 19/55 (34%), Positives = 25/55 (45%)
 Frame = -2

Query: 294 PPKHTFEQNSRIGNMWASPELKQNPGVNKEHLLDPAHVNPFTQGNSPENQAHHPP 348
           PP+HT +  S  G MW S +L  +P +    LLDP    P     +PE      P
Sbjct: 928 PPRHTDDTLSDTGLMWFSGKLLPSPSLVSASLLDPG---PVKLTRNPERWGFEAP 773
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|16716381|ref|NP_444322.1| lysyl-tRNA synthetase
isoform 2 [Mus musculus]
         (595 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

04140                                                                  34   0.21 
01075                                                                  32   0.63 
27047                                                                  30   3.1  
>04140
          Length = 1869

 Score = 33.9 bits (76), Expect = 0.21,   Method: Compositional matrix adjust.
 Identities = 13/45 (28%), Positives = 25/45 (55%)
 Frame = +2

Query: 525  MFIDENFCTALEYGLPPTAGWGMGIDRLTMFLTDSNNIKEVLLFP 569
             +ID+       YG  P  G+G+G++R   ++ +  +I+E  L+P
Sbjct: 1055 WYIDQR-----RYGSCPHGGYGLGVERFMCWILNRYHIREACLYP 1174
>01075
          Length = 1212

 Score = 32.3 bits (72), Expect = 0.63,   Method: Compositional matrix adjust.
 Identities = 11/33 (33%), Positives = 21/33 (63%)
 Frame = +2

Query: 537 YGLPPTAGWGMGIDRLTMFLTDSNNIKEVLLFP 569
           YG  P  G+G+G++R   ++ +  +I+E  L+P
Sbjct: 425 YGSCPHGGYGLGVERFMCWILNRYHIREACLYP 523
>27047
          Length = 444

 Score = 30.0 bits (66), Expect = 3.1,   Method: Composition-based stats.
 Identities = 23/73 (31%), Positives = 36/73 (49%), Gaps = 1/73 (1%)
 Frame = +2

Query: 211 LPHLHFGLKDKETRYRQRYLDL-ILNDFVRQKFIVRSKIITYIRSFLDELGFLEIETPMM 269
            P L   LKD E + +Q  + L + NDFVR+KF+    +   + SFL  L  + I + + 
Sbjct: 107 FPLLTVRLKDLEHKTQQMLILLEMANDFVRRKFLKTCCLWMMMMSFLPPLDCITIVSEI- 283

Query: 270 NIIPGGAVAKPFI 282
                  +A PF+
Sbjct: 284 -------IAVPFV 301
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31981138|ref|NP_067363.2| exostoses (multiple)-like 2
[Mus musculus]
         (330 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

37710                                                                  33   0.21 
18667                                                                  30   1.4  
04276                                                                  30   1.6  
02829                                                                  28   3.6  
>37710
          Length = 474

 Score = 32.7 bits (73), Expect = 0.21,   Method: Compositional matrix adjust.
 Identities = 21/57 (36%), Positives = 29/57 (50%)
 Frame = +2

Query: 150 VDDDTLISAQDLVFAFSIWQQFPDQIIGFVPRKHVSTSSGIYSYGGFELQTPGPGDG 206
           V+D T +  Q    +F++   F       VPRKH+++SS  Y  G  E Q P  GDG
Sbjct: 83  VNDKTCLFKQSPRSSFAVVCHF-----MAVPRKHIASSSSEYWIGFDEHQYPMSGDG 238
>18667
          Length = 1489

 Score = 30.0 bits (66), Expect = 1.4,   Method: Compositional matrix adjust.
 Identities = 11/32 (34%), Positives = 18/32 (56%)
 Frame = +1

Query: 216 ASFFNSKYLELFQKQPAAVHALIDETQNCDDI 247
           ASFF++ Y  +  KQ   V  ++D  Q C ++
Sbjct: 673 ASFFSTVYGRIILKQLGCVKVMVDRKQRCSNL 768
>04276
          Length = 1221

 Score = 29.6 bits (65), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 16/65 (24%), Positives = 30/65 (46%)
 Frame = -2

Query: 99  VWNNVGEKGPEELWNSLGPHPIPVIFKPQTANKMRNRLQVFPEVETNAVLMVDDDTLISA 158
           +W+N+       L++   P+PI  I++ QT + +  +  +F E  T  +  + D      
Sbjct: 968 LWHNIQI*SSTVLYSR*RPYPIQQIYRKQTKSNLSLQXSIFKEKTTIXIPYIADIEKTDT 789

Query: 159 QDLVF 163
           Q L F
Sbjct: 788 QILTF 774
>02829
          Length = 2024

 Score = 28.5 bits (62), Expect = 3.6,   Method: Compositional matrix adjust.
 Identities = 13/38 (34%), Positives = 19/38 (50%)
 Frame = +3

Query: 221 SKYLELFQKQPAAVHALIDETQNCDDIAMNFLVTRHTG 258
           +KYL L + Q A  HA +   + CD I +  +V    G
Sbjct: 474 NKYLRLLRNQKANFHAFVQYRKRCDLILILIMVNTLLG 587
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|149263480|ref|XP_127105.7| PREDICTED: similar to
tetratricopeptide repeat domain 7B isoform 1 [Mus musculus]
         (898 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

18090                                                                  34   0.22 
04645                                                                  34   0.31 
05964                                                                  30   3.2  
28154                                                                  30   3.5  
14040                                                                  30   6.3  
19977                                                                  29   6.5  
35264                                                                  29   9.4  
>18090
          Length = 772

 Score = 34.3 bits (77), Expect = 0.22,   Method: Compositional matrix adjust.
 Identities = 13/36 (36%), Positives = 17/36 (47%)
 Frame = -3

Query: 491 LAAKLCVGSLHWLEEAEKFAKTVVDVGEKTSEFKAK 526
           L + LC  S HW   + KFA T +   + T  F  K
Sbjct: 620 LTSNLCFSSFHWFSWSTKFACTSISCSDVT*SFSLK 513
>04645
          Length = 1075

 Score = 33.9 bits (76), Expect = 0.31,   Method: Compositional matrix adjust.
 Identities = 22/88 (25%), Positives = 41/88 (46%)
 Frame = +3

Query: 717 SVAASRVEQALSEVASSLQSSAPKQGPLHPWMTLAQIWLHAAEVYIGIGKPAEATACTQE 776
           ++A  R+E A+     +++S+           T A ++      Y+ +GKP +A     +
Sbjct: 474 AMAEGRLEDAIGFFTDAIKSNP----------TSALLYAKRGSAYLKMGKPKKAIHDCSK 623

Query: 777 AANLFPMSHNVLYMRGQVAELRGHFDEA 804
           A  L P S      RG+  +L GH++E+
Sbjct: 624 AIELNPDSAQGYKWRGKAHKLLGHWEES 707
>05964
          Length = 604

 Score = 30.4 bits (67), Expect = 3.2,   Method: Composition-based stats.
 Identities = 17/39 (43%), Positives = 24/39 (61%), Gaps = 4/39 (10%)
 Frame = -2

Query: 212 HVDREQDVITCYEK----AGDIALLYLQEIERVMLTNIQ 246
           H  R+   I+ YEK    +GDI+ LYLQ + +V  TNI+
Sbjct: 198 HSTRQTRQISTYEKETTNSGDISRLYLQHLVQVQYTNIK 82
>28154
          Length = 374

 Score = 30.4 bits (67), Expect = 3.5,   Method: Compositional matrix adjust.
 Identities = 14/60 (23%), Positives = 27/60 (45%)
 Frame = +1

Query: 424 LTIALGRRGQYEMLSECLERAMKFAFEEFHLWYQFALSLMAAGKSARAVKVLKECIRLKP 483
           L +     G+Y    +C + A++   ++  LW +   +L   G+S  AV      ++L P
Sbjct: 112 LGVLFNLSGEYNKAVDCFQAALQARPKDALLWNKLGATLANGGRSEEAVDAYHNALQLSP 291
>14040
          Length = 712

 Score = 29.6 bits (65), Expect = 6.3,   Method: Compositional matrix adjust.
 Identities = 21/58 (36%), Positives = 28/58 (48%), Gaps = 2/58 (3%)
 Frame = +1

Query: 64  CRSECQWERIPELVKQLSAKLIANDDMAELLLGESKLEQHLKE--KPLRQGASPRGPR 119
           C  +  W++ P    QL + L+   D  E L   S LEQ+LK   K + Q  S  GPR
Sbjct: 13  CTEKNHWDKTPASAFQLKSSLLNLLDNPEQLQEGSLLEQYLKSEIKKISQLGSSTGPR 186
>19977
          Length = 408

 Score = 29.3 bits (64), Expect = 6.5,   Method: Composition-based stats.
 Identities = 34/116 (29%), Positives = 48/116 (41%), Gaps = 1/116 (0%)
 Frame = -2

Query: 645 VKLESLCRGPDEALLTCKHMLQIWKSCYNLTNPSDSGRGSSLLDRTIADRRQLNTITLPD 704
           V L+SL +   +  L C  +++IWK C  L N   SGRG    D       +   I L  
Sbjct: 365 VLLQSL*QIIKQMQLEC--IVEIWKVCRMLNNKGSSGRGRGSKDDVACKNDR--CINLKS 198

Query: 705 FSDPETGS-VHATSVAASRVEQALSEVASSLQSSAPKQGPLHPWMTLAQIWLHAAE 759
            S P       AT +  SR     +EV    +  +P +  LH   T  Q+  H+ E
Sbjct: 197 ISSPRPSM*YSATQLPFSR-NWTSAEVGLCTEEISPMKNRLHS--TRQQVPPHSQE 39
>35264
          Length = 867

 Score = 28.9 bits (63), Expect = 9.4,   Method: Compositional matrix adjust.
 Identities = 26/97 (26%), Positives = 43/97 (44%)
 Frame = +3

Query: 801 FDEARRWYEEALSISPTHVKSMQRLALVLHQLGRYSLAEKILRDAVQVNSTAHEVWNGLG 860
           + EA   Y  A+++ P+        A     L +Y    K  + AVQ++ T  + +   G
Sbjct: 87  YKEALECYTCAINLCPSCAAYYGNRAATYMMLKKYREGLKDAQQAVQLDPTFVKGYIREG 266

Query: 861 EVLQAQGNDAAATECFLTALELEASSPAVPFTVIPRV 897
           +     GN  AA+  F   LEL+A + +   T + RV
Sbjct: 267 KCHLMLGNSMAASSNFNRVLELDAGN-STAVTELKRV 374
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|10946674|ref|NP_067327.1| crystallin, beta B3 [Mus
musculus]
         (211 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

03022                                                                  32   0.23 
10186                                                                  28   2.1  
16410                                                                  27   4.3  
>03022
          Length = 2255

 Score = 31.6 bits (70), Expect = 0.23,   Method: Compositional matrix adjust.
 Identities = 17/69 (24%), Positives = 30/69 (43%), Gaps = 1/69 (1%)
 Frame = -3

Query: 107  LHIDGPDHK-LHLFENPAFSGRKMEIVDDDVPSLWAHGFQDRVASIRVINGTWVGYEFPG 165
            L  D P  K L + + P+ SG  M+I+  + P LW  G    +  +  +  TW+    P 
Sbjct: 1995 LRXDPPLVKALKMSKRPSVSGNPMKILRSNRPGLWRAGSTFSMMLVAPMTYTWLLSPHPS 1816

Query: 166  YRGRQYVFE 174
             +   ++  
Sbjct: 1815 IKASSWLVT 1789
>10186
          Length = 349

 Score = 28.5 bits (62), Expect = 2.1,   Method: Compositional matrix adjust.
 Identities = 10/30 (33%), Positives = 18/30 (60%)
 Frame = +3

Query: 120 ENPAFSGRKMEIVDDDVPSLWAHGFQDRVA 149
           ++P F  ++M  ++     LWA GFQ+ +A
Sbjct: 117 KSPFFC*KRMRFINGQAKCLWASGFQNLLA 206
>16410
          Length = 360

 Score = 27.3 bits (59), Expect = 4.3,   Method: Compositional matrix adjust.
 Identities = 16/45 (35%), Positives = 23/45 (51%), Gaps = 3/45 (6%)
 Frame = -3

Query: 34  FQGKRCEL---SAECPNLTDSLLEKVGSIQVESGPWLAFERRAFR 75
           F G  C L   S  C N+T+   E+ G + +  G +L  E +AFR
Sbjct: 247 FAGLLCHLVCTSITCYNITNGNREREGVLLIAYGDFLDIETQAFR 113
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|18875408|ref|NP_573503.1| acyl-CoA thioesterase 8
[Mus musculus]
         (320 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

12375                                                                  32   0.23 
14668                                                                  28   5.9  
>12375
          Length = 1104

 Score = 32.3 bits (72), Expect = 0.23,   Method: Compositional matrix adjust.
 Identities = 13/32 (40%), Positives = 24/32 (75%), Gaps = 1/32 (3%)
 Frame = -3

Query: 288  VHGRLWRRDGVLAVTCAQEGVIRLK-PQVSES 318
            + GR+W +DG L ++ AQEGV+R + P++ ++
Sbjct: 1099 LTGRMWTQDGRLVISVAQEGVLRTRIPRIPDA 1004
>14668
          Length = 399

 Score = 27.7 bits (60), Expect = 5.9,   Method: Compositional matrix adjust.
 Identities = 9/17 (52%), Positives = 13/17 (76%)
 Frame = -3

Query: 266 FRADHWMLYECESPWAG 282
           F+ + ++LYECES W G
Sbjct: 340 FKTEQYVLYECESDWIG 290
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|21704202|ref|NP_663576.1| hypothetical protein
LOC234586 [Mus musculus]
         (326 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

29791                                                                  32   0.24 
>29791
          Length = 386

 Score = 32.3 bits (72), Expect = 0.24,   Method: Compositional matrix adjust.
 Identities = 13/43 (30%), Positives = 22/43 (51%)
 Frame = +3

Query: 138 FWRGMQKVVPQPVCSNGGQNLAAGERDPDQGGAQIPEPCGTGD 180
           +WR  + V+P+  CS+G  NL    RD      ++ + C + D
Sbjct: 225 YWR--RGVIPRK*CSSGKDNLYRSRRDSSSAANRLRDRCKSMD 347
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|42734496|ref|NP_613053.3| D6Wsu176e protein [Mus
musculus]
         (227 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

08964                                                                  32   0.24 
22352                                                                  32   0.29 
01960                                                                  28   2.4  
18077                                                                  27   7.0  
>08964
          Length = 2157

 Score = 31.6 bits (70), Expect = 0.24,   Method: Compositional matrix adjust.
 Identities = 19/71 (26%), Positives = 30/71 (42%)
 Frame = -3

Query: 148  ATYDDGATKLTDEARRLIAELGSTSITSLGFRDNWVFCGGKGIKTKSPFEQHIKNNKETN 207
            A   D     T EA   +A+L ++   +          GG G  T  P E+H ++ + T 
Sbjct: 1123 AMLKDAGKPFTKEA--AMAKLAASETATFNAHQAIQILGGMGFVTDMPAERHYRDARITE 950

Query: 208  KYEGWPEVVEM 218
             YEG  E+  +
Sbjct: 949  IYEGTSEIQRL 917
>22352
          Length = 736

 Score = 31.6 bits (70), Expect = 0.29,   Method: Compositional matrix adjust.
 Identities = 16/45 (35%), Positives = 23/45 (51%), Gaps = 3/45 (6%)
 Frame = -2

Query: 58  CGISKACPEKHFAFKMASGAANV---VGPKICLEDNVLMSGVKNN 99
           CGI   CPEKH   K+ S + ++   + P + L   VL   +K N
Sbjct: 234 CGIEAVCPEKHMLSKIHSPSLHICSSIHPSLSLLFPVLAEQIKRN 100
>01960
          Length = 1477

 Score = 28.5 bits (62), Expect = 2.4,   Method: Compositional matrix adjust.
 Identities = 13/38 (34%), Positives = 20/38 (52%)
 Frame = -1

Query: 21   YVISQVFEIKMDASLGNLFARSALDSAIRSTKPPRYKC 58
            YV+SQ  ++K  + +GN F  S  DS+       + KC
Sbjct: 1306 YVVSQREQLKQTSKIGNTFVWSFPDSSWYQNNQSKTKC 1193
>18077
          Length = 1227

 Score = 26.9 bits (58), Expect = 7.0,   Method: Compositional matrix adjust.
 Identities = 12/25 (48%), Positives = 13/25 (52%)
 Frame = -1

Query: 40  ARSALDSAIRSTKPPRYKCGISKAC 64
           AR AL     S  PPRY CG  + C
Sbjct: 384 ARPALSGPASSPAPPRYACG*RQTC 310
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|84370025|ref|NP_001028300.1| Bardet-Biedl syndrome 1
[Mus musculus]
         (593 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

21333                                                                  33   0.27 
>21333
          Length = 877

 Score = 33.5 bits (75), Expect = 0.27,   Method: Compositional matrix adjust.
 Identities = 23/56 (41%), Positives = 28/56 (50%), Gaps = 5/56 (8%)
 Frame = +3

Query: 470 ALESSLSPMSTTAREPLKLHAVVQGLG-----PTFKLTLHLQNTSTARPVLGLHVC 520
           A+E SL  MSTT R  L L A +QG       PT K+  H+ +T T   V  L  C
Sbjct: 45  AVERSLHCMSTTTRTALNLVAQIQGRKRWVTVPTRKVMCHVPDTCTL*RVQRLQCC 212
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|161484642|ref|NP_080949.2| apolipoprotein O [Mus
musculus]
         (198 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

03231                                                                  31   0.28 
07614                                                                  30   0.92 
16274                                                                  28   3.0  
07191                                                                  27   3.6  
06571                                                                  27   5.2  
00289                                                                  26   9.0  
>03231
          Length = 1257

 Score = 31.2 bits (69), Expect = 0.28,   Method: Compositional matrix adjust.
 Identities = 27/93 (29%), Positives = 42/93 (45%), Gaps = 13/93 (13%)
 Frame = +1

Query: 79  QEIYSHTKPKVD----HFVQWGVDNYNYLQNAPPGFFPRL---------GVIGFAGFVGL 125
           +E ++H + +      H V+W   ++N L     GFFP L         G+ GF  FVG 
Sbjct: 565 RETHTHRETQTHTLYIHRVRWRERDHNTLSYGFYGFFPLLFHYVHCFVYGLKGFGTFVGF 744

Query: 126 LFARGSKIKKLVYPPFFMGLGASVYYPQQAITI 158
           L     K +K  +  F + LG S   P + +T+
Sbjct: 745 L---ALKFRK--FXXFLIILGNS---PSETVTL 819
>07614
          Length = 523

 Score = 29.6 bits (65), Expect = 0.92,   Method: Compositional matrix adjust.
 Identities = 14/39 (35%), Positives = 20/39 (51%), Gaps = 6/39 (15%)
 Frame = -1

Query: 165 KLYDWGLRGYIVIEDLWKQNFQ------KPGNVKNSPGN 197
           +L+  GLRG   + DL+ +NFQ      + G     PGN
Sbjct: 271 ELFQQGLRGLASLSDLFAENFQLTRFVHRLGATFTEPGN 155
>16274
          Length = 439

 Score = 27.7 bits (60), Expect = 3.0,   Method: Compositional matrix adjust.
 Identities = 16/64 (25%), Positives = 34/64 (53%), Gaps = 2/64 (3%)
 Frame = -1

Query: 20  RVYAAPKKDSPHKSYMKIDELSLYSVPEGQSKYVEEPRTQLEENISQLRHHCEPY--TSF 77
           R+ +   K    + ++K+ +L  ++      ++++ P+T+L ENIS+ R    P+     
Sbjct: 196 RILSLSLKMIMQRMFLKVSQLLFFN---DWKQFLDLPKTKLNENISR*RIKVIPHKRDES 26

Query: 78  CQEI 81
           CQ+I
Sbjct: 25  CQQI 14
>07191
          Length = 2615

 Score = 27.3 bits (59), Expect = 3.6,   Method: Compositional matrix adjust.
 Identities = 10/26 (38%), Positives = 13/26 (50%)
 Frame = +2

Query: 87  PKVDHFVQWGVDNYNYLQNAPPGFFP 112
           P+ D + QWG      +   PPG FP
Sbjct: 470 PRSDRYGQWGAKCPTNVHVLPPGIFP 547
>06571
          Length = 517

 Score = 26.9 bits (58), Expect = 5.2,   Method: Compositional matrix adjust.
 Identities = 7/17 (41%), Positives = 13/17 (76%)
 Frame = -1

Query: 74  YTSFCQEIYSHTKPKVD 90
           +T FC  +Y+HT+P++ 
Sbjct: 412 HTHFCTRVYTHTEPRIH 362
>00289
          Length = 899

 Score = 26.2 bits (56), Expect = 9.0,   Method: Compositional matrix adjust.
 Identities = 9/26 (34%), Positives = 17/26 (65%)
 Frame = +2

Query: 150 YYPQQAITIAQITGEKLYDWGLRGYI 175
           ++PQQ++T+  I+  +   WGL  Y+
Sbjct: 227 HWPQQSVTLTMISNWRSEKWGLLPYL 304
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6754444|ref|NP_034759.1| kinesin-associated protein 3
[Mus musculus]
         (772 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

14657                                                                  34   0.28 
15086                                                                  31   2.4  
11272                                                                  30   2.7  
08233                                                                  29   6.3  
>14657
          Length = 918

 Score = 33.9 bits (76), Expect = 0.28,   Method: Compositional matrix adjust.
 Identities = 21/81 (25%), Positives = 40/81 (49%), Gaps = 1/81 (1%)
 Frame = -3

Query: 587 KSGIIPALIELLNAQQEDDEFVCQIIYVFYQMVFHQATRDVIIKETQAPAYLIDLMHDKN 646
           KSG IPAL++LL++  E   F    I   + ++ HQ    + ++       ++ L+   N
Sbjct: 523 KSGGIPALVKLLSSPMESVLFYA--ITTLHNLLLHQEGSKMAVRLAGGLQKMVALLQRNN 350

Query: 647 N-EIRKVCDNTLDIIAEYDEE 666
           N +   +  + L I+A  ++E
Sbjct: 349 NVKFLAITTDCLQILAYGNQE 287
>15086
          Length = 548

 Score = 30.8 bits (68), Expect = 2.4,   Method: Composition-based stats.
 Identities = 21/81 (25%), Positives = 40/81 (49%), Gaps = 1/81 (1%)
 Frame = +1

Query: 587 KSGIIPALIELLNAQQEDDEFVCQIIYVFYQMVFHQATRDVIIKETQAPAYLIDLMHDKN 646
           KSG IPAL++LL++  E   F    I   + ++ HQ    + ++       ++ L+   N
Sbjct: 244 KSGGIPALVKLLSSPVESVLFYA--ITTLHNLLLHQEGSKMAVRMAGGLQKMVALLQRNN 417

Query: 647 N-EIRKVCDNTLDIIAEYDEE 666
           N +   +  + L I+A  ++E
Sbjct: 418 NVKFLAITTDCLQILAYGNQE 480
>11272
          Length = 1530

 Score = 30.4 bits (67), Expect = 2.7,   Method: Compositional matrix adjust.
 Identities = 12/43 (27%), Positives = 26/43 (60%)
 Frame = -1

Query: 216  HYKIGALCMNIIDHELKRHELWQEELSKKKKAVDEDLENQTLR 258
            H K+    ++I++H + ++++W +  +K K + D  LEN  L+
Sbjct: 1233 HSKMSPQNVDIVEHYVDQYKVWAKTTNKPKVSTDTTLENTKLK 1105
>08233
          Length = 2477

 Score = 29.3 bits (64), Expect = 6.3,   Method: Compositional matrix adjust.
 Identities = 16/45 (35%), Positives = 24/45 (53%)
 Frame = -3

Query: 714  ILERPDLFYNSDGLITSEGAISPDFFNDFHLQNGDVVGQHAFPGS 758
            I+E+    YN+DG       I P    D+ ++NG +VG   FPG+
Sbjct: 2313 IMEKDGSIYNADG-------IHPRELEDYKIENGTIVG---FPGA 2209
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|170650609|ref|NP_032410.2| inositol
polyphosphate-1-phosphatase [Mus musculus]
         (396 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

25328                                                                  33   0.29 
>25328
          Length = 468

 Score = 32.7 bits (73), Expect = 0.29,   Method: Compositional matrix adjust.
 Identities = 17/41 (41%), Positives = 24/41 (58%), Gaps = 2/41 (4%)
 Frame = -3

Query: 311 KWDSCAAHAILRAMGGGI--VDMKECLERSPDTGLDLPQLL 349
           KWD CA  AIL A+GG +  +D K     S D+ +++  LL
Sbjct: 430 KWDICAGEAILHALGGAMTAIDGKPISYGSHDSAVNMDGLL 308
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|46849812|ref|NP_034363.1| fibronectin 1 [Mus
musculus]
         (2477 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

17679                                                                  34   0.30 
07945                                                                  33   1.2  
19544                                                                  33   1.5  
19200                                                                  32   2.3  
>17679
          Length = 509

 Score = 30.4 bits (67), Expect(2) = 0.30,   Method: Compositional matrix adjust.
 Identities = 24/74 (32%), Positives = 33/74 (44%), Gaps = 7/74 (9%)
 Frame = +3

Query: 1907 PRRARVTDATETTITISW---RTKTETITGFQVDAIPANGQTPV----QRSISPDVRSYT 1959
            PR  R   A+ TTI +SW         I G++V       + PV    Q+ +  D R  T
Sbjct: 138  PRNVRARAASSTTIVVSWSEPEIPNGIIQGYRV-FYTRKPEEPVFFWEQQEVKNDNRLTT 314

Query: 1960 ITGLQPGTDYKIHL 1973
            I+GL P   Y I +
Sbjct: 315  ISGLDPNQTYTISI 356

 Score = 23.5 bits (49), Expect(2) = 0.30,   Method: Composition-based stats.
 Identities = 7/14 (50%), Positives = 12/14 (85%)
 Frame = +1

Query: 2005 TPNSLLVSWQAPRA 2018
            +PN++LV W AP++
Sbjct: 463  SPNAILVKWDAPKS 504

 Score = 34.3 bits (77), Expect = 0.63,   Method: Compositional matrix adjust.
 Identities = 23/86 (26%), Positives = 42/86 (48%), Gaps = 6/86 (6%)
 Frame = +3

Query: 1541 PRDLEVIASTPTSLLISWEPPAVS---VRYYRITYGETGGNSPV---QEFTVPGSKSTAT 1594
            PR++   A++ T++++SW  P +    ++ YR+ Y       PV   ++  V       T
Sbjct: 138  PRNVRARAASSTTIVVSWSEPEIPNGIIQGYRVFYTRK-PEEPVFFWEQQEVKNDNRLTT 314

Query: 1595 INNIKPGADYTITLYAVTGRGDSPAS 1620
            I+ + P   YTI++ A +  G  P S
Sbjct: 315  ISGLDPNQTYTISILAYSSIGPGPMS 392

 Score = 32.0 bits (71), Expect = 3.0,   Method: Compositional matrix adjust.
 Identities = 23/63 (36%), Positives = 29/63 (46%), Gaps = 6/63 (9%)
 Frame = +3

Query: 825 SIVVRWSRPQAP---ITGYRIVYSPSVEGSSTELNLPETANS---VTLSDLQPGVQYNIT 878
           +IVV WS P+ P   I GYR+ Y+   E         E  N     T+S L P   Y I+
Sbjct: 174 TIVVSWSEPEIPNGIIQGYRVFYTRKPEEPVFFWEQQEVKNDNRLTTISGLDPNQTYTIS 353

Query: 879 IYA 881
           I A
Sbjct: 354 ILA 362

 Score = 30.4 bits (67), Expect = 9.9,   Method: Compositional matrix adjust.
 Identities = 21/76 (27%), Positives = 33/76 (43%), Gaps = 5/76 (6%)
 Frame = +3

Query: 1995 APSNLRFLTTTPNSLLVSW---QAPRARITGYIIKYEKXXXXXXXXXXXXXXXXTE--AT 2049
            AP N+R    +  +++VSW   + P   I GY + Y +                     T
Sbjct: 135  APRNVRARAASSTTIVVSWSEPEIPNGIIQGYRVFYTRKPEEPVFFWEQQEVKNDNRLTT 314

Query: 2050 ITGLEPGTEYTIYVIA 2065
            I+GL+P   YTI ++A
Sbjct: 315  ISGLDPNQTYTISILA 362
>07945
          Length = 2023

 Score = 33.5 bits (75), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 24/82 (29%), Positives = 39/82 (47%), Gaps = 4/82 (4%)
 Frame = -3

Query: 1635 PSQMQVTDVQDNSISVRWLP----STSPVTGYRVTTTPKNGLGPSKTKTASPDQTEMTIE 1690
            PSQ   TD+  NS+++ W P    S+  +  Y V  T  +        T S    +  ++
Sbjct: 1697 PSQPVATDITHNSLTLSWQPPRRNSSDTIYAYTVEKTXPSDXKGWTIVTTSCQGNQYQVK 1518

Query: 1691 GLQPTVEYVVSVYAQNRNGESQ 1712
             L P+ +YV  V A+N +G S+
Sbjct: 1517 KLSPSSQYVFRVRAENIHGVSK 1452
>19544
          Length = 1421

 Score = 33.1 bits (74), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 40/168 (23%), Positives = 77/168 (45%), Gaps = 14/168 (8%)
 Frame = +2

Query: 1333 YDISVITLINGGE---SAPTTLTQQTAVPP--PTDLRFTNIGPDTMRVTW-APPPSIELT 1386
            Y++ V+ +   G    S P T+    A P   P++++  N    +++VTW APPP  +  
Sbjct: 20   YEVQVLAVNGKGRGPPSTPATIYVGEAAPTEGPSNVQAVNKSASSIQVTWVAPPPETQNG 199

Query: 1387 NL----LVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYLVSV---SSVYEQHESIP 1439
             L    ++ Y    + E+  EL+   ++  ++L +L   T Y ++V   +   E   S  
Sbjct: 200  GLSGYKVLYYKQSSSAEE--ELTRITAETHILLESLETFTVYFIAVQPYNLAGEGPRSAL 373

Query: 1440 LRGRQKTGLDS-PTGFDSSDITANSFTVHWVAPRAPITGYIIRHHAEH 1486
            +  +   G+ S P     ++IT     VH+  P  P  G+I+ +  ++
Sbjct: 374  VSAQTSEGVPSAPQSIRFTNITMRQLMVHFDPPTTP-NGHILLYEMQY 514

 Score = 32.7 bits (73), Expect = 2.1,   Method: Compositional matrix adjust.
 Identities = 42/219 (19%), Positives = 95/219 (43%), Gaps = 18/219 (8%)
 Frame = +2

Query: 1514 YVVSIIAVNGREESPP-----LIGQQATVSDIPRDLEVIASTPTSLLISWEPPAVSVRY- 1567
            Y V ++AVNG+   PP     +   +A  ++ P +++ +  + +S+ ++W  P    +  
Sbjct: 20   YEVQVLAVNGKGRGPPSTPATIYVGEAAPTEGPSNVQAVNKSASSIQVTWVAPPPETQNG 199

Query: 1568 ----YRITYGETGGNSPVQEFTVPGSKSTATINNIKPGADYTITLYAVTGRGDSPASSKP 1623
                Y++ Y +   +S  +E T   +++   + +++    Y I +      G+ P S+  
Sbjct: 200  GLSGYKVLYYKQ-SSSAEEELTRITAETHILLESLETFTVYFIAVQPYNLAGEGPRSALV 376

Query: 1624 VSINYKTEIDKPSQMQVTDVQDNSISVRWLPSTSP---VTGYRVTTTPKNG-----LGPS 1675
             +   +     P  ++ T++    + V + P T+P   +  Y +   PK+      L P 
Sbjct: 377  SAQTSEGVPSAPQSIRFTNITMRQLMVHFDPPTTPNGHILLYEMQYFPKDESRYGFLAPK 556

Query: 1676 KTKTASPDQTEMTIEGLQPTVEYVVSVYAQNRNGESQPL 1714
            +   A  ++T + +  L+  V Y   + A    G+ + L
Sbjct: 557  RILRA--NETRVVVTELEKRVWYKFIISANTSIGKGESL 667
>19200
          Length = 436

 Score = 32.3 bits (72), Expect = 2.3,   Method: Compositional matrix adjust.
 Identities = 31/114 (27%), Positives = 52/114 (45%), Gaps = 6/114 (5%)
 Frame = -2

Query: 1551 PTSLLISWEPPAVSVRYYRITYGETGGNSPVQ---EFTVPGSKSTATINNIKPGADYTIT 1607
            PTS+ +SW+ P   V  Y+I Y      +PV    +    G  + A I+N++P   Y + 
Sbjct: 435  PTSIEVSWDDPNFPVAGYKIFYNMFA--TPVMYVWQQMETGPYTVADISNLEPHTVYAVR 262

Query: 1608 LYA--VTGRGDSPASSKPVSINYKTEIDKPSQ-MQVTDVQDNSISVRWLPSTSP 1658
            + A  V GR  + + +   S+N   E +   +  +VT    N + + W P   P
Sbjct: 261  VQAKSVDGRFGNLSETVTTSVNGDPERENVVRNFRVTSRLTNLVRLSWSPPKKP 100
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|109809747|ref|NP_001035949.1| golgi autoantigen,
golgin subfamily a, 7 [Mus musculus]
         (137 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

24587                                                                  30   0.31 
07433                                                                  28   1.7  
>24587
          Length = 2023

 Score = 30.0 bits (66), Expect = 0.31,   Method: Composition-based stats.
 Identities = 14/29 (48%), Positives = 18/29 (62%)
 Frame = -2

Query: 46  TVRTLNNLYAEAEKLGGQSYLEGCLACLT 74
           ++R L  LYAE E L G S  E C+A L+
Sbjct: 639 SLRPLQELYAEREDLFGASVKENCVAALS 553
>07433
          Length = 793

 Score = 27.7 bits (60), Expect = 1.7,   Method: Compositional matrix adjust.
 Identities = 14/50 (28%), Positives = 26/50 (52%), Gaps = 2/50 (4%)
 Frame = +3

Query: 75  AYTIFLCMETHY--EKVLKKVSKYIQEQNEKIYAPQGLLLTDPIERGLRV 122
           ++ + LC    +  +K+ +   KYI++ N  ++  Q  LLT   ER  R+
Sbjct: 249 SFILLLCCCCFFSPDKLFQSPLKYIRDVNHLVFQTQHFLLTLRCERLARI 398
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|13385098|ref|NP_079912.1| hypothetical protein
LOC66566 [Mus musculus]
         (190 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

01642                                                                  31   0.31 
17843                                                                  28   2.6  
19129                                                                  27   3.5  
18673                                                                  27   5.9  
01279                                                                  26   8.1  
22512                                                                  26   8.8  
>01642
          Length = 1406

 Score = 30.8 bits (68), Expect = 0.31,   Method: Compositional matrix adjust.
 Identities = 20/60 (33%), Positives = 29/60 (48%), Gaps = 1/60 (1%)
 Frame = -1

Query: 3   RHVFLTGPPGVGKTTLIQKAIEVLQSSGLPVDGF-YTQEVRQEGKRIGFDVVTLSGAQGP 61
           R V + GPPG GKT L +       ++ + V G  + Q+   EG R+  DV  L+    P
Sbjct: 890 RGVLMYGPPGCGKTMLAKAVAHHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAP 711
>17843
          Length = 772

 Score = 28.1 bits (61), Expect = 2.6,   Method: Compositional matrix adjust.
 Identities = 11/20 (55%), Positives = 14/20 (70%)
 Frame = +1

Query: 1   MSRHVFLTGPPGVGKTTLIQ 20
            +R + L GPPG GKTTL +
Sbjct: 181 WNRVILLHGPPGTGKTTLCK 240
>19129
          Length = 1020

 Score = 27.3 bits (59), Expect = 3.5,   Method: Compositional matrix adjust.
 Identities = 21/76 (27%), Positives = 33/76 (43%), Gaps = 8/76 (10%)
 Frame = +1

Query: 5   VFLTGPPGVGKTTLIQKAIEVLQSSGLPVDGF-YTQEVRQEGKRIGFDVVTLSGAQGP-- 61
           V L GPPG GKT L +      + + + V G    Q+   EG R+  ++  ++    P  
Sbjct: 598 VLLYGPPGTGKTLLARAVAHHTECTFIRVSGSELVQKFIGEGSRMVRELFVMAREHAPSI 777

Query: 62  -----LSRVGSQPLPG 72
                +  +GS  L G
Sbjct: 778 IFMDEIDSIGSSRLEG 825
>18673
          Length = 583

 Score = 26.6 bits (57), Expect = 5.9,   Method: Compositional matrix adjust.
 Identities = 9/13 (69%), Positives = 12/13 (92%)
 Frame = -1

Query: 167 FNVTRDNRNSLLP 179
           FN+TRDN N++LP
Sbjct: 349 FNITRDNTNTMLP 311
>01279
          Length = 2183

 Score = 26.2 bits (56), Expect = 8.1,   Method: Compositional matrix adjust.
 Identities = 14/31 (45%), Positives = 17/31 (54%)
 Frame = -3

Query: 3    RHVFLTGPPGVGKTTLIQKAIEVLQSSGLPV 33
            R V L GPPG GKT +   A+ + Q  G  V
Sbjct: 1914 RAVLLAGPPGTGKTAI---ALAIAQELGNKV 1831
>22512
          Length = 562

 Score = 26.2 bits (56), Expect = 8.8,   Method: Compositional matrix adjust.
 Identities = 11/16 (68%), Positives = 13/16 (81%)
 Frame = -1

Query: 5   VFLTGPPGVGKTTLIQ 20
           V + GPP VGKTTL+Q
Sbjct: 286 VAIVGPPKVGKTTLLQ 239
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|18250288|ref|NP_543027.1| hypothetical protein
LOC28106 [Mus musculus]
         (166 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

00833                                                                  30   0.32 
33915                                                                  26   7.7  
>00833
          Length = 2454

 Score = 30.4 bits (67), Expect = 0.32,   Method: Compositional matrix adjust.
 Identities = 14/44 (31%), Positives = 21/44 (47%), Gaps = 1/44 (2%)
 Frame = -3

Query: 87   IWRPQGKSYLYFTQFKAELRG-AEIEYAMAYSKAAFERESDVPL 129
            IW PQGK + + TQF  EL     +   ++  K  F    ++ L
Sbjct: 2023 IWCPQGKPHTFHTQFLVELTSHCNLHNKLSACKDCFCTGCEIIL 1892
>33915
          Length = 862

 Score = 25.8 bits (55), Expect = 7.7,   Method: Compositional matrix adjust.
 Identities = 17/45 (37%), Positives = 26/45 (57%)
 Frame = +3

Query: 96  LYFTQFKAELRGAEIEYAMAYSKAAFERESDVPLKSEEFEVTKTA 140
           L+F     E+RG  I YA +Y K A ER+ +  L++E  E+ K +
Sbjct: 171 LFFEMLLLEIRGKTISYA-SYKKKA-ERKQEEMLQNEISEIEKNS 299
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|10946808|ref|NP_067413.1| FGF intracellular binding
protein [Mus musculus]
         (357 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

06546                                                                  32   0.33 
11361                                                                  28   7.5  
>06546
          Length = 1345

 Score = 32.3 bits (72), Expect = 0.33,   Method: Compositional matrix adjust.
 Identities = 14/39 (35%), Positives = 22/39 (56%)
 Frame = -2

Query: 312 WPLSDVRLFLSQYSASVHSLDGFRHQALWDRYMGTLRGC 350
           W +S+   F   ++AS HS   F H +LW+++M T   C
Sbjct: 918 WTISETPTFSXXFAASCHS---FSHDSLWEQWMCTATLC 811
>11361
          Length = 665

 Score = 27.7 bits (60), Expect = 7.5,   Method: Compositional matrix adjust.
 Identities = 13/29 (44%), Positives = 19/29 (65%)
 Frame = -1

Query: 60  YRTFHMLERLLHAPPKLLHQLIFQIPPSR 88
           YRT+++  R LH  PK+L    FQI P++
Sbjct: 260 YRTYYLHSRKLHX-PKILSXCQFQIRPAK 177
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|47777353|ref|NP_957682.1| Fgfr1 oncogene partner [Mus
musculus]
         (379 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

04373                                                                  32   0.33 
32836                                                                  28   4.4  
>04373
          Length = 959

 Score = 32.3 bits (72), Expect = 0.33,   Method: Compositional matrix adjust.
 Identities = 19/63 (30%), Positives = 28/63 (44%)
 Frame = +2

Query: 66  LNTKDGRLVASLVAEFLQFFNLDFTLAVFHPETSTIQGLEGRENLAQDLGIIEAEGTVGG 125
           L  KDG LV  L A  + +  L  TL   HP T+ ++ L      + D  +I     +  
Sbjct: 218 LLVKDGLLVPCLAASVITYLFLSSTLRPLHPHTTAVKLLVSLS*QSADYMLIHRFSILSQ 397

Query: 126 PLL 128
           P+L
Sbjct: 398 PIL 406
>32836
          Length = 1493

 Score = 28.5 bits (62), Expect = 4.4,   Method: Compositional matrix adjust.
 Identities = 16/45 (35%), Positives = 21/45 (46%)
 Frame = +1

Query: 66   LNTKDGRLVASLVAEFLQFFNLDFTLAVFHPETSTIQGLEGRENL 110
            L  KDG LV  L A  + +  L  TL   HP T+ ++ L     L
Sbjct: 1183 LLVKDGLLVPCLAASVITYLFLSSTLRPLHPHTTAVKLLHTLSLL 1317
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|77681962|ref|NP_848770.2| ankyrin 2, brain isoform 2
[Mus musculus]
         (1050 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

17179                                                                  34   0.33 
20757                                                                  33   0.89 
13104                                                                  30   4.8  
09423                                                                  30   5.9  
>17179
          Length = 523

 Score = 33.9 bits (76), Expect = 0.33,   Method: Composition-based stats.
 Identities = 15/31 (48%), Positives = 19/31 (61%)
 Frame = +1

Query: 185 GEGLASRLIEVGPSGAQFLGPVIVEIPHFAA 215
           GE + S L+  GP G +FL PV + IPH A 
Sbjct: 1   GETMLSPLVMCGPQGLEFLVPVTLNIPHCAG 93
>20757
          Length = 1062

 Score = 32.7 bits (73), Expect = 0.89,   Method: Compositional matrix adjust.
 Identities = 27/98 (27%), Positives = 46/98 (46%), Gaps = 3/98 (3%)
 Frame = -1

Query: 600 MTSEKNPQDEQ-ERMEERLAYIADHLGFSWTELARELDFTEEQIHQIRIENP-NSLQDQS 657
           + +++N  D Q E   + +  ++  +   W  L REL  ++  + QIR++N  +   + +
Sbjct: 588 IANKRNITDSQAEPTHDHMDIVSREISGDWQRLGRELKLSDAXLEQIRLDNHLHGAYEIN 409

Query: 658 HALLKYWLERDGKHATDTILIECLTKINRMDIV-HLLE 694
           + +LK W E      T   L   L  I R DI  HL E
Sbjct: 408 YQMLKKWKEISAP-VTVHALALALATIVRGDIADHLSE 298
>13104
          Length = 1094

 Score = 30.0 bits (66), Expect = 4.8,   Method: Compositional matrix adjust.
 Identities = 17/48 (35%), Positives = 26/48 (54%)
 Frame = -2

Query: 166 VTCRLVKRHRLATMPPMVEGEGLASRLIEVGPSGAQFLGPVIVEIPHF 213
           V+  L+  H+   +P   E E +A  LIE   S A F+ P+ + +PHF
Sbjct: 514 VSTDLMTAHKRLKLP---ESEMIACPLIEYDASDAVFITPLEICLPHF 380
>09423
          Length = 1212

 Score = 29.6 bits (65), Expect = 5.9,   Method: Composition-based stats.
 Identities = 12/37 (32%), Positives = 19/37 (51%)
 Frame = -1

Query: 444  SQVYREIICVPYMAKFVVFAKSHDPIEARLRCFCMTD 480
            S V++ + CV    K   F+ +HD +  +L C C  D
Sbjct: 1044 STVWQHVFCVSAPVKHASFSPAHDCVANKLPCCCSGD 934
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|148277096|ref|NP_700462.2| dedicator of cyto-kinesis
3 [Mus musculus]
         (2030 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

12834                                                                  35   0.34 
37761                                                                  32   3.9  
21115                                                                  31   5.1  
18050                                                                  31   5.3  
>12834
          Length = 550

 Score = 35.0 bits (79), Expect = 0.34,   Method: Composition-based stats.
 Identities = 27/91 (29%), Positives = 39/91 (42%), Gaps = 1/91 (1%)
 Frame = +1

Query: 1784 PTHRDRPSSAMYPAAILENGQPPNFQRALFQQVVGACKPCSDPNLSMAEKGHYSLHFDAF 1843
            PT   RP +++ P   L N   P        + + + K  + P L   +  H+       
Sbjct: 190  PTANLRPITSLRPITSLRNITSP--------RNIASPKSIASPRLMATQLAHH------- 324

Query: 1844 HHPLGDTPPA-LPARTLRKSPLHPIPASPTS 1873
               L   P A LPA TLR +P HP+ A PT+
Sbjct: 325  RATLAPVPIAMLPALTLRITPAHPLMAPPTT 417
>37761
          Length = 592

 Score = 31.6 bits (70), Expect = 3.9,   Method: Composition-based stats.
 Identities = 14/29 (48%), Positives = 17/29 (58%)
 Frame = +2

Query: 1147 VSEGKGDESYRELFGLLTQLFGPYPSLLE 1175
            V  G+G   Y ELFG  T +F  Y SLL+
Sbjct: 77   VCVGRGRGGYLELFGFFTGIFSSYSSLLQ 163
>21115
          Length = 419

 Score = 30.8 bits (68), Expect = 5.1,   Method: Composition-based stats.
 Identities = 16/36 (44%), Positives = 20/36 (55%), Gaps = 1/36 (2%)
 Frame = +3

Query: 75  YETVVPLEDSIVTEVTTTLQEW-ASLWKQLYVKHKV 109
           Y  V+ LE+S  T VT TLQEW    W+  Y K  +
Sbjct: 285 YGCVI*LENSAQTVVTCTLQEWLQRFWEWCYFKKNI 392
>18050
          Length = 448

 Score = 30.8 bits (68), Expect = 5.3,   Method: Composition-based stats.
 Identities = 17/47 (36%), Positives = 25/47 (53%), Gaps = 1/47 (2%)
 Frame = +3

Query: 16 SFRGSVPQGLVLEIGETVQILEKC-EGWYRGVSTKKPNVKGLFPANY 61
          S+    P  L LE+G+ V +  K  +GWY+G   +   V G FP +Y
Sbjct: 39 SYESDEPDVLQLELGDVVNVSRKLPDGWYQGERIRDGAV-GWFPGSY 176
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|25092662|ref|NP_081052.2| vacuolar protein sorting 25
[Mus musculus]
         (176 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

33648                                                                  31   0.35 
36857                                                                  27   5.8  
>33648
          Length = 452

 Score = 30.8 bits (68), Expect = 0.35,   Method: Compositional matrix adjust.
 Identities = 19/58 (32%), Positives = 29/58 (50%)
 Frame = +2

Query: 50  TVMEAQESPLFNNVKLQRKLPVESIQIVLEELRKKGNLEWLDKNKSSFLIMWRRPEEW 107
           +VM + + P  NN KL       S   + E   K+G+L+ LDK+  +FLI  +  E  
Sbjct: 140 SVMTSDQVPAANNDKL-------SPSGMQESTEKEGDLDNLDKDLGAFLIGPKSNESG 292
>36857
          Length = 697

 Score = 26.6 bits (57), Expect = 5.8,   Method: Compositional matrix adjust.
 Identities = 11/19 (57%), Positives = 14/19 (73%)
 Frame = +2

Query: 119 GQNNSVFTLYELTSGEDTE 137
           GQNN +F   ++TS EDTE
Sbjct: 23  GQNNVIFIKADVTSDEDTE 79
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|32469491|ref|NP_862896.1| optineurin [Mus musculus]
         (584 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

15731                                                                  33   0.35 
>15731
          Length = 1725

 Score = 33.1 bits (74), Expect = 0.35,   Method: Compositional matrix adjust.
 Identities = 36/118 (30%), Positives = 58/118 (49%), Gaps = 12/118 (10%)
 Frame = +1

Query: 221 NCTED--ARSCAEFE-----ELTVSQLLLCLREGNQKVERLEVALREAKERISDFEKKAN 273
           +CTED  AR  A  E     E + +QLL+ L+E N  +E+LEV L++ +  ++D +K   
Sbjct: 706 SCTEDMEARLAAASEQRLAAEASKAQLLVELKEKNNXLEQLEVKLKQCESELADVQKAMQ 885

Query: 274 GHSSTEKQTARRADREK-----EDKGQESVGSEVETLSIQVTSLFKELQEAHTKLSEA 326
             + T  Q   + +  K     +    E+   + E L  +V SL KE+ E   K  +A
Sbjct: 886 SMTDTNTQLTTQCESYKMVTDAQHAKMEAAAEDHEVLLERVKSLEKEVCEMQLKADKA 1059
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|13385682|ref|NP_080449.1| hypothetical protein
LOC67463 [Mus musculus]
         (558 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

12363                                                                  33   0.38 
>12363
          Length = 1603

 Score = 32.7 bits (73), Expect = 0.38,   Method: Compositional matrix adjust.
 Identities = 14/33 (42%), Positives = 20/33 (60%)
 Frame = +3

Query: 19  RSVSTDLQEEYEELLRYAIVNPNVECSASQPSH 51
           RS+STD +  +EEL   ++ NP+  C A  P H
Sbjct: 606 RSLSTDFKSTFEEL-TLSLPNPDCSCPAKSPPH 701
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|119964702|ref|NP_083767.2| hypothetical protein
LOC75964 [Mus musculus]
         (822 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

16350                                                                  33   0.39 
12538                                                                  31   1.8  
>16350
          Length = 1108

 Score = 33.5 bits (75), Expect = 0.39,   Method: Compositional matrix adjust.
 Identities = 15/41 (36%), Positives = 19/41 (46%)
 Frame = -1

Query: 122 WFESYRETFLQSMPASDHEFLNHYLACMLVASSGEAEPMEQ 162
           W    +  FL     SDH FLN  ++C L   SG A  + Q
Sbjct: 955 WLSCPKTPFLVPFTVSDHAFLNKQISCWLPDGSGHASNLSQ 833
>12538
          Length = 1418

 Score = 31.2 bits (69), Expect = 1.8,   Method: Compositional matrix adjust.
 Identities = 16/64 (25%), Positives = 29/64 (45%), Gaps = 4/64 (6%)
 Frame = +3

Query: 345 HDRIRQFIQEFTFRGL----LPHIEKTIRQLNDQLISRKGLSRSLFSATKKWFSGSKVPE 400
           H R RQ       RG     +PH+  T+ +   + ++R+  +R+     KKW   +K   
Sbjct: 936 HCRCRQMTMRRKTRGRGVLGMPHLSVTVNRCRRKAVTRRTGTRTSLVGRKKWHKSAKNQS 1115

Query: 401 KSIN 404
           + +N
Sbjct: 1116QPLN 1127
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|22165362|ref|NP_083449.1| nucleoredoxin [Mus
musculus]
         (156 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

12488                                                                  30   0.39 
>12488
          Length = 1288

 Score = 30.0 bits (66), Expect = 0.39,   Method: Compositional matrix adjust.
 Identities = 13/19 (68%), Positives = 15/19 (78%)
 Frame = -3

Query: 71  SADGSAEEMLDFMRELHGS 89
            ADGSAEE+LD +R  HGS
Sbjct: 833 GADGSAEELLDLVRLGHGS 777
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|21703970|ref|NP_663468.1| complexin 4 [Mus musculus]
         (160 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

15121                                                                  30   0.40 
>15121
          Length = 2573

 Score = 30.0 bits (66), Expect = 0.40,   Method: Compositional matrix adjust.
 Identities = 13/41 (31%), Positives = 24/41 (58%)
 Frame = +3

Query: 61  AAFTQKKAERACLRVHLRDKYRLPKSEMDETQIQLAGDDVD 101
           A +T+++A R C R    DK  +P+S  + TQ+ +   D++
Sbjct: 222 ACWTERRASRTCSRCWREDKGAIPRS--NSTQVTIKVSDIN 338
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|9790285|ref|NP_062754.1| vacuolar protein sorting 29
[Mus musculus]
         (182 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

25603                                                                  30   0.41 
28070                                                                  28   3.0  
>25603
          Length = 453

 Score = 30.4 bits (67), Expect = 0.41,   Method: Compositional matrix adjust.
 Identities = 12/30 (40%), Positives = 17/30 (56%)
 Frame = -2

Query: 7   GDLHIPHRCNSLPAKFKKLLVPGKIQHILC 36
           G L +P R  SLPA    ++VPG +   +C
Sbjct: 383 GSLAVPARARSLPAGTGSVVVPGSLLPSVC 294
>28070
          Length = 504

 Score = 27.7 bits (60), Expect = 3.0,   Method: Compositional matrix adjust.
 Identities = 13/34 (38%), Positives = 18/34 (52%)
 Frame = +3

Query: 34  ILCTGNLCTKESYDYLKTLAGDVHIVRGDFDENL 67
           I CT N     SY Y++T     H++R D+  NL
Sbjct: 165 INCTANRLYYRSYGYIQTHLFQFHLLRFDYMXNL 266
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31542488|ref|NP_666328.2| Vac14 homolog [Mus
musculus]
         (782 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

34104                                                                  33   0.42 
15067                                                                  32   0.79 
08670                                                                  30   3.6  
>34104
          Length = 369

 Score = 33.1 bits (74), Expect = 0.42,   Method: Composition-based stats.
 Identities = 13/50 (26%), Positives = 27/50 (54%)
 Frame = -1

Query: 580 KFASTMVHTLNTILLTSTELFQLRNQLKDLQTPESQNLFCCLYRSWCHNP 629
           K+ S ++H     +L++++L++         +   QN+ CC++R  C NP
Sbjct: 324 KYGSNILHIAEYTVLSTSQLYKPSYAKYGATSCTLQNILCCVHRHNCTNP 175
>15067
          Length = 1062

 Score = 32.3 bits (72), Expect = 0.79,   Method: Compositional matrix adjust.
 Identities = 25/84 (29%), Positives = 41/84 (48%), Gaps = 4/84 (4%)
 Frame = +3

Query: 15  VRALNDKLYEKRKVAALEIEKLVRDFVAQNNTMQIKHVIQTLS---QEFALSQHPHSRKG 71
           V+ + +K  EKR+  ALE EKL  +  +Q  T + +   Q       +  L++  +SRK 
Sbjct: 663 VKTVAEKAEEKRQQQALEDEKLFGEIGSQQKTKKGRRSAQKSKISDSDSLLNREENSRKY 842

Query: 72  GLIGLAACSIALGKDSGL-YLKEL 94
                A+ +   GK+ G  YL E+
Sbjct: 843 TTRAKASKTKGRGKEEGWQYLDEV 914
>08670
          Length = 1307

 Score = 30.0 bits (66), Expect = 3.6,   Method: Compositional matrix adjust.
 Identities = 16/35 (45%), Positives = 19/35 (54%)
 Frame = +2

Query: 451 LSDESDEVVLKDLEVLAEIASSPAGQTDDPGAPDG 485
           LSDE D V  K + V   +AS PA    DP  P+G
Sbjct: 845 LSDEEDYVAPKSIPVPQPLASMPADSKMDPKNPEG 949
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|26986547|ref|NP_758459.1| bromodomain and WD repeat
domain containing 2 [Mus musculus]
         (1223 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

01327                                                                  34   0.44 
36859                                                                  32   1.2  
03798                                                                  32   2.0  
01768                                                                  31   2.6  
29912                                                                  31   2.9  
02147                                                                  31   3.6  
27475                                                                  31   3.7  
02960                                                                  30   4.3  
12806                                                                  30   4.5  
>01327
          Length = 2215

 Score = 33.9 bits (76), Expect = 0.44,   Method: Compositional matrix adjust.
 Identities = 31/144 (21%), Positives = 65/144 (45%), Gaps = 1/144 (0%)
 Frame = +3

Query: 481 KTYQPLLAV-GTSNGSVLVYHLTSGLLHKELSVHSCEVKGIEWTSLTSFLSFAASTPNNM 539
           ++ QP L + G+ + SV++Y   +G L    + H  E+  + + +  + + F+AS    +
Sbjct: 63  RSIQPGLCLSGSKDKSVVLYDYQNGRLEDRWTGHDREITKVCYGASCNGM-FSASRDKTI 239

Query: 540 GLVRNELQLVDLPTGRSTAFRGDRGNDESPIEMIKVSHLKQYLAVVFKDKPLELWDIRTC 599
            + +          G S + R   G+D   +  I ++     L    +D  + +WD+ T 
Sbjct: 240 KMWQR---------GNSHSIRDFIGHD-MVVTAIHLNTDNTLLCSGSRDNTVRIWDVETG 389

Query: 600 TLLREMSKSFPAITALEWSPSHNL 623
             LR+ +     +T ++W P  +L
Sbjct: 390 ACLRQNNIPQNLVTDVKWLPGSHL 461
>36859
          Length = 1034

 Score = 32.3 bits (72), Expect = 1.2,   Method: Composition-based stats.
 Identities = 15/33 (45%), Positives = 20/33 (60%)
 Frame = +3

Query: 10  VSARTLTGALNAHNKAAVDWGWQGLIAYGCHSL 42
           +S++  TG LNAH    V  GW+GL  +  HSL
Sbjct: 339 LSSKKQTGXLNAHCTVGV--GWRGLFTFSFHSL 431
>03798
          Length = 1598

 Score = 31.6 bits (70), Expect = 2.0,   Method: Composition-based stats.
 Identities = 21/83 (25%), Positives = 36/83 (43%), Gaps = 12/83 (14%)
 Frame = -3

Query: 754 IRFAPGKGNQKLIAMYNDGAEVWDTKEVQMVSSLRSGRNVTFRILDV------------D 801
           IR    KGN   I  Y      W T   Q ++ + + +N    IL +            D
Sbjct: 357 IRLKT*KGNDTXITKYCH----WRTYVSQALNXMTAEKNAPLSILSIALLQKTEPKQXTD 190

Query: 802 WCTSDKVILASDDGCIRVLEMSM 824
           WC + +  ++++ GC R+ E+S+
Sbjct: 189 WC*AHRTKMSTNLGCFRMEEISI 121
>01768
          Length = 1424

 Score = 31.2 bits (69), Expect = 2.6,   Method: Compositional matrix adjust.
 Identities = 23/107 (21%), Positives = 49/107 (45%), Gaps = 10/107 (9%)
 Frame = +3

Query: 747 HRSWVRKIRFAPGKGNQKLIAMYNDGAEVWDTKEVQMVSSLRSGRNVTFRILDV-DWCTS 805
           H   V  ++++P +GN       +    +W+T++    +++ +      R ++V +W   
Sbjct: 834 HTDSVEDVQWSPNEGNVFASCSVDRTLRIWNTQQKPSKANVLTVPEAHSRDINVINWNPI 1013

Query: 806 DKVILAS--DDGCIRVLEMSM-------KSTCFRMDEQELVEPVWCP 843
           +K +LAS  DDG I++ ++ M           F++  Q +    W P
Sbjct: 1014EKHLLASGGDDGIIKIWDLRMFRNKPVSAQASFKLHSQPVTSLEWNP 1154
>29912
          Length = 510

 Score = 31.2 bits (69), Expect = 2.9,   Method: Compositional matrix adjust.
 Identities = 32/138 (23%), Positives = 58/138 (42%), Gaps = 5/138 (3%)
 Frame = +3

Query: 487 LAVGTSNGSVLVYHLTSGLLHKELSVHSCEVKGIEWTSLTSFLSFAASTPNNMGLVRNEL 546
           LA+GTS G V V+ +T     + ++ H+  V  + W    SF+  + S   N  +  +++
Sbjct: 54  LALGTSTGEVQVWDVTQQKKLRTMAGHAARVGSLSW---NSFIVSSGSRSGN--IHHHDV 218

Query: 547 QLVDLPTGRSTAFRGDRGNDESPIEMIKVSHLKQYLAVVFKDKPLELWDIR-----TCTL 601
           ++ D   G  +            +  ++ S   +YLA    D  L +W  +     +   
Sbjct: 219 RVADHHVGTLSGH-------SQEVCGLRWSPDGKYLASGANDNLLCVWPAQVTGGNSTQP 377

Query: 602 LREMSKSFPAITALEWSP 619
           L   S+   A+ AL W P
Sbjct: 378 LHTFSQHQAAVKALAWCP 431
>02147
          Length = 1547

 Score = 30.8 bits (68), Expect = 3.6,   Method: Compositional matrix adjust.
 Identities = 31/151 (20%), Positives = 59/151 (39%), Gaps = 4/151 (2%)
 Frame = +2

Query: 588 DKPLELWDIRTCTLLREMSKSFPAITALEWSPSHNLKSLRKKQLATREAMARQTVVSDAE 647
           DK + LW + TC  +++++   P  T+L  SP  N   +   Q                 
Sbjct: 488 DKTVRLWSLETCQEVQQLTFDTPP-TSLTLSPDKNTIIVTHSQ----------------N 616

Query: 648 LGAVESSVISLLQEAESKAELSQNI--SAREHFVFTDNDGQVYHLTVEGNSVKDSARIPP 705
           +   ++  +  +++ E++A +S      +   FV    D ++Y    E     +S +   
Sbjct: 617 IAFYQADTLREMKKFEAEAPISSASLHQSERFFVAGGEDFKMYKFDYETGKEIESFK--- 787

Query: 706 DGSMGSITCIAWK--GDTLVLGDMDGNLNFW 734
            G  G + C+ +   G+    G  DG L  W
Sbjct: 788 -GHFGPVHCVRFSPDGELYASGSEDGTLRLW 877
>27475
          Length = 369

 Score = 30.8 bits (68), Expect = 3.7,   Method: Compositional matrix adjust.
 Identities = 19/78 (24%), Positives = 37/78 (47%)
 Frame = +2

Query: 746 THRSWVRKIRFAPGKGNQKLIAMYNDGAEVWDTKEVQMVSSLRSGRNVTFRILDVDWCTS 805
           +H  WV  + ++P + +  L   Y++  ++WDT+  +  ++L        RIL VDW   
Sbjct: 62  SHTGWVTGVDWSPTREHLFLSGSYDNVLKLWDTRSPK--ATLYDMNWHEDRILAVDWSIP 235

Query: 806 DKVILASDDGCIRVLEMS 823
           + ++    D  + V   S
Sbjct: 236 ELLLSGGVDNKLHVFSYS 289
>02960
          Length = 1577

 Score = 30.4 bits (67), Expect = 4.3,   Method: Compositional matrix adjust.
 Identities = 25/108 (23%), Positives = 47/108 (43%), Gaps = 6/108 (5%)
 Frame = +2

Query: 722  LVLGDMDGNLNFWDLKARVSRG------IPTHRSWVRKIRFAPGKGNQKLIAMYNDGAEV 775
            L+ G  D ++    +  R S G        +H  WV  + ++P + +  L   Y++  ++
Sbjct: 1124 LITGSADRHVRL--VDPRCSEGETVKCAFTSHTGWVTGVDWSPTREHLFLSGSYDNVLKL 1297

Query: 776  WDTKEVQMVSSLRSGRNVTFRILDVDWCTSDKVILASDDGCIRVLEMS 823
            WDT+  +  ++L        RIL VDW   + ++    D  + V   S
Sbjct: 1298 WDTRSPK--ATLYDMNWHEDRILAVDWSIPELLLSGGVDNKLHVFSYS 1435
>12806
          Length = 961

 Score = 30.4 bits (67), Expect = 4.5,   Method: Compositional matrix adjust.
 Identities = 24/119 (20%), Positives = 49/119 (41%), Gaps = 3/119 (2%)
 Frame = +3

Query: 725 GDMDGNLNFWDLKARVSRGIPT--HRSWVRKIRFAPGKGNQKLIAMYNDGA-EVWDTKEV 781
           G  D NL  W++       +    H  WV  +RF     N  +++  ND   +VWD   +
Sbjct: 345 GGRDKNLKIWNIMGECKYTVDANAHTDWVTCVRFHQDTKNPIVVSASNDKTIKVWDNHTM 524

Query: 782 QMVSSLRSGRNVTFRILDVDWCTSDKVILASDDGCIRVLEMSMKSTCFRMDEQELVEPV 840
            + ++   G       LD+   +++ ++  S DG      ++  S   ++D  + +  +
Sbjct: 525 TLKNTF-VGHKAQITALDM---STNYLVSGSKDGIAMTWNVAEGSFVGKIDCDDQINAI 689
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|9506971|ref|NP_062283.1| profilin 2 [Mus musculus]
         (140 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

29621                                                                  30   0.44 
>29621
          Length = 415

 Score = 29.6 bits (65), Expect = 0.44,   Method: Compositional matrix adjust.
 Identities = 12/40 (30%), Positives = 20/40 (50%)
 Frame = +2

Query: 10  NLMCDGCCQEAAIVGYCDAKYVWAATAGGVFQSITPVEID 49
           +++ +   Q+  I G+C   YVW    G  F+S+  V  D
Sbjct: 80  HVLLENT*QQHGIKGWCSYSYVWWPNNGKHFKSLIXVPRD 199
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|146134519|ref|NP_001035485.2| hypothetical protein
LOC68646 isoform 2 [Mus musculus]
         (430 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

19311                                                                  32   0.46 
11621                                                                  32   0.49 
>19311
          Length = 1071

 Score = 32.0 bits (71), Expect = 0.46,   Method: Compositional matrix adjust.
 Identities = 16/30 (53%), Positives = 18/30 (60%)
 Frame = -2

Query: 312 NRVAAQAVEDVLHIARRQGNLTLPLNKDLV 341
           NRVA Q V     +A R GNLTLP  +D V
Sbjct: 989 NRVAKQVVHKTDRLAERIGNLTLPRERDQV 900

 Score = 28.5 bits (62), Expect = 5.6,   Method: Compositional matrix adjust.
 Identities = 23/78 (29%), Positives = 36/78 (46%)
 Frame = -2

Query: 149 DGTMLLAASKVLDRLKPVIGVNTDPERSEGHLCLPVRYTHSFPEALRRFSRGEFRWLWRQ 208
           + ++ L  SKVL  ++ V+   TDP     H+C+  +    +  A   F R   RW W+ 
Sbjct: 326 NWSLALTISKVLISIQSVL---TDPY---CHVCMEPKIGALYQRAKPEFERIARRWTWKY 165

Query: 209 RIRLYLEGTGINPTPVDL 226
            +  Y     + PT VDL
Sbjct: 164 AMHDY-----VMPTDVDL 126
>11621
          Length = 1209

 Score = 32.0 bits (71), Expect = 0.49,   Method: Compositional matrix adjust.
 Identities = 16/67 (23%), Positives = 33/67 (49%)
 Frame = +1

Query: 315 AAQAVEDVLHIARRQGNLTLPLNKDLVEKVTNEYNESLLYSPEEPKILFSIREPIANRVF 374
           A +  ++VLH A+   ++        + +  N+ N   + +   PK+L++IR+   N++F
Sbjct: 868 ATKTTQNVLHTAQHHSHMQTSQLSSPIGQTINQSNNQPIRAQSMPKVLYTIRK--*NQIF 1041

Query: 375 SSSRQRC 381
               Q C
Sbjct: 1042FQKTQTC 1062
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6681035|ref|NP_031799.1| crystallin, beta B2 [Mus
musculus]
         (205 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

11966                                                                  30   0.47 
07302                                                                  27   6.3  
>11966
          Length = 815

 Score = 30.4 bits (67), Expect = 0.47,   Method: Compositional matrix adjust.
 Identities = 17/53 (32%), Positives = 27/53 (50%)
 Frame = -3

Query: 142 SSVRVQSGTWVGYQYPGYRGLQYLLEKGDYKDNSDFGAPHPQVQSVRRIRDMQ 194
           S++ V + TW        RG+   L  GD++DN  FG+    V   R +RD++
Sbjct: 348 STLLVHTDTW------SSRGMGLFLRSGDHRDNVRFGS--SGVFCTRALRDLK 214
>07302
          Length = 970

 Score = 26.9 bits (58), Expect = 6.3,   Method: Compositional matrix adjust.
 Identities = 14/40 (35%), Positives = 19/40 (47%), Gaps = 3/40 (7%)
 Frame = +2

Query: 29  GHSHELSGPCPNLKETGMEKAGSVLVQAGPW---VGYEQA 65
           GH   LS   P LK T    A +  + + PW   +GY +A
Sbjct: 701 GHPQNLSATSPPLKGTAASAAETACILSTPWKRSIGYFRA 820
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31541828|ref|NP_076320.2| hypothetical protein
LOC76568 [Mus musculus]
         (301 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

15671                                                                  31   0.48 
01607                                                                  28   5.0  
31214                                                                  28   5.4  
33082                                                                  28   6.6  
>15671
          Length = 2548

 Score = 31.2 bits (69), Expect = 0.48,   Method: Compositional matrix adjust.
 Identities = 18/66 (27%), Positives = 33/66 (50%), Gaps = 5/66 (7%)
 Frame = +2

Query: 241  CAILDIPFYKSRIQSLHLLFSLYSEFKNSQHFKA---LAEGKKVFTPPPNSASQAGDA-- 295
            C I +I + K+   ++H+  ++YS+  +SQ  K+   + + KK       S  Q G+   
Sbjct: 2255 CTICNIMYTKTTPTTIHICVTIYSQCGSSQQCKSSTDITKAKKQAHTKSGSLKQEGEGTI 2434

Query: 296  ETLTFI 301
            +TL F 
Sbjct: 2435 DTL*FC 2452
>01607
          Length = 2534

 Score = 28.1 bits (61), Expect = 5.0,   Method: Compositional matrix adjust.
 Identities = 13/21 (61%), Positives = 16/21 (76%)
 Frame = -1

Query: 119 PDGKPDHLGLLVLDEPSTKQS 139
           PD K D LGLLV+DEP+ + S
Sbjct: 128 PDLKCDGLGLLVVDEPAGECS 66
>31214
          Length = 551

 Score = 27.7 bits (60), Expect = 5.4,   Method: Compositional matrix adjust.
 Identities = 12/37 (32%), Positives = 18/37 (48%)
 Frame = -2

Query: 225 PTVEIDCSLAEYIDMICAILDIPFYKSRIQSLHLLFS 261
           P +  DCS   +    C +  I FY   +Q  HL+F+
Sbjct: 493 PVLCRDCSNLLFTSAFCVVFSIYFYSFHLQLCHLIFT 383
>33082
          Length = 729

 Score = 27.7 bits (60), Expect = 6.6,   Method: Compositional matrix adjust.
 Identities = 11/36 (30%), Positives = 23/36 (63%), Gaps = 1/36 (2%)
 Frame = -3

Query: 218 LLGKVSLPTVEID-CSLAEYIDMICAILDIPFYKSR 252
           L+G V +P V +  C   + + +IC +L++PF+ ++
Sbjct: 586 LVGMVIVPLVSMSVCFCLQRLQLICGLLNLPFFLTK 479
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|30794138|ref|NP_082568.1| protein phosphatase
methylesterase 1 [Mus musculus]
         (386 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

19087                                                                  32   0.50 
03845                                                                  32   0.60 
07769                                                                  30   2.4  
>19087
          Length = 468

 Score = 31.6 bits (70), Expect = 0.50,   Method: Compositional matrix adjust.
 Identities = 16/60 (26%), Positives = 30/60 (50%)
 Frame = +1

Query: 107 IVALDLRGHGETKVKNSEDLSAETMAKDVGNVVEAMYGDLPPPVMLIGHSMGGAIAVHTA 166
           +  + LRG  E+++K     S++    ++ + +    GD   P +  GHSMG  ++  TA
Sbjct: 289 VYGITLRGR-ESRMKEKPCASSQETVAEIASTIATELGD--KPFLFFGHSMGALLSYETA 459
>03845
          Length = 1326

 Score = 31.6 bits (70), Expect = 0.60,   Method: Compositional matrix adjust.
 Identities = 19/73 (26%), Positives = 32/73 (43%)
 Frame = +2

Query: 94  VFTAAIISRVQCRIVALDLRGHGETKVKNSEDLSAETMAKDVGNVVEAMYGDLPPPVMLI 153
           V+T   +   +  +V  D RG G++  + +E    E +      V +  +     PV L 
Sbjct: 311 VYTYTALRGQEFHVVTFDYRGFGDSTGEATESHMVEDLVTVFRWVKKRAWKS---PVFLW 481

Query: 154 GHSMGGAIAVHTA 166
           GHS+GG +    A
Sbjct: 482 GHSLGGGVVTQAA 520
>07769
          Length = 457

 Score = 29.6 bits (65), Expect = 2.4,   Method: Compositional matrix adjust.
 Identities = 11/25 (44%), Positives = 17/25 (68%)
 Frame = +2

Query: 273 KEDDMETKKDHPYTWRIELAKTEKY 297
           KEDD  T++ HP  WR ++ K ++Y
Sbjct: 98  KEDDTATEESHPLNWRPDIFKKKRY 172
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|63746579|ref|XP_621044.1| PREDICTED: hypothetical
protein [Mus musculus]
         (163 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

13619                                                                  30   0.50 
21172                                                                  28   2.5  
18142                                                                  27   5.0  
01907                                                                  26   6.3  
29726                                                                  26   7.3  
>13619
          Length = 1117

 Score = 30.0 bits (66), Expect = 0.50,   Method: Compositional matrix adjust.
 Identities = 15/36 (41%), Positives = 21/36 (58%)
 Frame = +3

Query: 72  TTITGYLQEDGKTYKTQYQGDNHYELVKETPENLVF 107
           TTIT  L++D + +K      NH +L+KE P N  F
Sbjct: 312 TTITHTLEKDWQAWKLLEVLPNHLDLLKEFPPNFNF 419
>21172
          Length = 476

 Score = 27.7 bits (60), Expect = 2.5,   Method: Compositional matrix adjust.
 Identities = 27/78 (34%), Positives = 30/78 (38%), Gaps = 15/78 (19%)
 Frame = +1

Query: 69  CSLTTITGYLQEDGKTYKTQYQGDNHYELVKETPENL---------------VFYSENVD 113
           CSLT   G   +D   YK + +    Y   KET ENL               V  SEN  
Sbjct: 184 CSLTNNDGIDIKDLMKYKLEKKTIKGYSKAKETKENLLTAECDILMPCATQKVITSENA- 360

Query: 114 RADRKTKLIFVLGNKPLT 131
             D K KLI    N P T
Sbjct: 361 -KDIKAKLILEGANGPTT 411
>18142
          Length = 489

 Score = 26.6 bits (57), Expect = 5.0,   Method: Compositional matrix adjust.
 Identities = 13/37 (35%), Positives = 22/37 (59%)
 Frame = -1

Query: 93  NHYELVKETPENLVFYSENVDRADRKTKLIFVLGNKP 129
           N  E+VK      +F+S ++D A ++ +LIF+  N P
Sbjct: 363 NLDEIVKACRGRNLFFSTDIDTAIQEAELIFISVNTP 253
>01907
          Length = 1360

 Score = 26.2 bits (56), Expect = 6.3,   Method: Compositional matrix adjust.
 Identities = 10/25 (40%), Positives = 17/25 (68%), Gaps = 2/25 (8%)
 Frame = -2

Query: 72  TTITGY--LQEDGKTYKTQYQGDNH 94
           +T+ G+   Q+DG+TY  Q  G++H
Sbjct: 789 STLAGH*PCQQDGQTYPVQLSGESH 715
>29726
          Length = 2379

 Score = 26.2 bits (56), Expect = 7.3,   Method: Compositional matrix adjust.
 Identities = 13/24 (54%), Positives = 16/24 (66%)
 Frame = +1

Query: 60   TFYVLENGQCSLTTITGYLQEDGK 83
            ++Y +   Q S TT TGY QEDGK
Sbjct: 2233 SYYGIHRSQLSSTT-TGYFQEDGK 2301
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|83745122|ref|NP_031641.2| catenin, delta 1 isoform 1
[Mus musculus]
         (938 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

22653                                                                  33   0.50 
15086                                                                  33   0.59 
14657                                                                  31   1.8  
06072                                                                  30   6.1  
06510                                                                  30   6.6  
>22653
          Length = 1347

 Score = 33.1 bits (74), Expect = 0.50,   Method: Compositional matrix adjust.
 Identities = 23/76 (30%), Positives = 39/76 (51%), Gaps = 2/76 (2%)
 Frame = +3

Query: 386 AAAYLQHLCYRNDKVKTDVRK--LKGIPILVGLLDHPKKEVHLGACGALKNISFGRDQDN 443
           +AA+    C  N K   ++ +  + G+ ++V LL    KEV    C A+ NI+  +D++N
Sbjct: 45  SAAWAICPCIENAKDAGEMVRSFVGGLELIVSLLKSEDKEVLAAVCAAIANIA--KDEEN 218

Query: 444 KIAIKNCDGVPALVRL 459
              I +   VP L +L
Sbjct: 219 LAVITDHGVVPMLAKL 266
>15086
          Length = 548

 Score = 33.1 bits (74), Expect = 0.59,   Method: Composition-based stats.
 Identities = 25/75 (33%), Positives = 36/75 (48%), Gaps = 1/75 (1%)
 Frame = +1

Query: 409 GIPILVGLLDHPKKEVHLGACGALKNISFGRDQDNKIAIKNC-DGVPALVRLLRKARDMD 467
            IP L+ LL    + V   A   +  +S  + + ++ AI N    + AL+R L    DM+
Sbjct: 1   AIPELIKLLSDEDQVVVCQAAMMVHQLS--KKEASRHAIMNSPQMIAALIRALATTDDME 174

Query: 468 LTEVITGTLWNLSSH 482
            T    GTL NLS H
Sbjct: 175 TTRCAAGTLHNLSHH 219

 Score = 32.0 bits (71), Expect = 1.1,   Method: Composition-based stats.
 Identities = 35/116 (30%), Positives = 48/116 (41%), Gaps = 1/116 (0%)
 Frame = +1

Query: 368 LPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPILV-GLLDHPKKEVHL 426
           +PE+I +L      V   AA  +  L  +       +   + I  L+  L      E   
Sbjct: 4   IPELIKLLSDEDQVVVCQAAMMVHQLSKKEASRHAIMNSPQMIAALIRALATTDDMETTR 183

Query: 427 GACGALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSH 482
            A G L N+S  R     +AI    G+PALV+LL    +  L   IT TL NL  H
Sbjct: 184 CAAGTLHNLSHHRQ--GLLAIFKSGGIPALVKLLSSPVESVLFYAIT-TLHNLLLH 342
>14657
          Length = 918

 Score = 31.2 bits (69), Expect = 1.8,   Method: Compositional matrix adjust.
 Identities = 23/55 (41%), Positives = 28/55 (50%)
 Frame = -3

Query: 428 ACGALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSH 482
           A G L N+S  R     +AI    G+PALV+LL    +  L   IT TL NL  H
Sbjct: 580 AAGTLHNLSHHRQ--GLLAIFKSGGIPALVKLLSSPMESVLFYAIT-TLHNLLLH 425

 Score = 29.6 bits (65), Expect = 5.8,   Method: Compositional matrix adjust.
 Identities = 35/132 (26%), Positives = 59/132 (44%), Gaps = 1/132 (0%)
 Frame = -3

Query: 352 SLRKGMPPPSNWRQPELPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIP 411
           +L +G+  PS    P+ P  +  L      +K    A +  + Y++D    D+   + IP
Sbjct: 916 TLPEGVQIPSTQVHPDEPTAVQRLSEPSQMLKH---AVVNLINYQDD---ADLAT-RAIP 758

Query: 412 ILVGLLDHPKKEVHLGACGALKNISFGRDQDNKIAIKNC-DGVPALVRLLRKARDMDLTE 470
            L+ LL      V   A   +  +S  + + ++ AI N    + AL+R +    D++ T 
Sbjct: 757 ELIKLLXDEDXVVVYQAAMMVHQLS--KKEASRHAIMNSPQMIAALIRAMANTEDIETTR 584

Query: 471 VITGTLWNLSSH 482
              GTL NLS H
Sbjct: 583 CAAGTLHNLSHH 548
>06072
          Length = 1397

 Score = 29.6 bits (65), Expect = 6.1,   Method: Compositional matrix adjust.
 Identities = 22/64 (34%), Positives = 31/64 (48%), Gaps = 1/64 (1%)
 Frame = +1

Query: 385 NAAAYLQHLCYRNDKVKTDVRKLK-GIPILVGLLDHPKKEVHLGACGALKNISFGRDQDN 443
           NA   L +LC R      D  K+   +P+L  LL H  K+V   AC AL  +S G ++  
Sbjct: 598 NAVWCLSNLC-RGKNPPPDFTKVSPALPVLARLLFHTDKDVLADACWALSYLSDGPNEKI 774

Query: 444 KIAI 447
           +  I
Sbjct: 775 QTVI 786
>06510
          Length = 2037

 Score = 29.6 bits (65), Expect = 6.6,   Method: Compositional matrix adjust.
 Identities = 25/92 (27%), Positives = 43/92 (46%), Gaps = 7/92 (7%)
 Frame = -1

Query: 400  VKTDVRKLKGIPILVGLLDHPKK-------EVHLGACGALKNISFGRDQDNKIAIKNCDG 452
            + T +  +  +P++V ++ H          EV      AL NI  G D  + +A +N   
Sbjct: 1017 IVTQMMTMGFLPLIVDIIVHVAMTGQIKTGEVATPMLRALGNICCGPDDYSLMACENPRL 838

Query: 453  VPALVRLLRKARDMDLTEVITGTLWNLSSHDS 484
            +PA++RLL    +  L  V+  T W +S+  S
Sbjct: 837  MPAILRLL----ECPLPHVVKETTWVMSNMTS 754
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|21311873|ref|NP_077181.1| heat shock factor binding
protein 1 [Mus musculus]
         (76 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

09200                                                                  29   0.51 
15814                                                                  27   2.1  
>09200
          Length = 945

 Score = 28.9 bits (63), Expect = 0.51,   Method: Compositional matrix adjust.
 Identities = 12/39 (30%), Positives = 25/39 (64%)
 Frame = -2

Query: 26  KFQIMSDQIIGRIDDMSSRIDDLEKNIADLMTQAGVEEL 64
           K  +M + +I  I+ M+ R++++EKN+   M +  +EE+
Sbjct: 212 KLDVMMNSLIPLINTMNQRLENIEKNLKPEMLENKIEEI 96
>15814
          Length = 1661

 Score = 26.9 bits (58), Expect = 2.1,   Method: Compositional matrix adjust.
 Identities = 12/39 (30%), Positives = 24/39 (61%)
 Frame = +3

Query: 26  KFQIMSDQIIGRIDDMSSRIDDLEKNIADLMTQAGVEEL 64
           K  +M +  I  I+ M+ R++++EKN+   M +  +EE+
Sbjct: 396 KLDVMMNSQIPLINTMNQRLENIEKNLKPEMIEHKIEEI 512
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31982535|ref|NP_849245.2| spermatogenesis associated
7 [Mus musculus]
         (582 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

04901                                                                  32   0.51 
>04901
          Length = 1042

 Score = 32.3 bits (72), Expect = 0.51,   Method: Compositional matrix adjust.
 Identities = 26/73 (35%), Positives = 37/73 (50%), Gaps = 1/73 (1%)
 Frame = +1

Query: 279 KTSSKDSEVNINQVPNYTRNGAEDKIAPLPSQGQNLAWDSI-QDGILQQSSERASCKLST 337
           KT +  ++ N    PN+  NG   K+ P+P Q     W SI Q+ IL  +SE  S     
Sbjct: 346 KTHTGPNQSNTFVNPNFVNNGG--KMPPMPKQSSRAIWGSILQEQIL--TSEVGS----- 498

Query: 338 EFSPDSKIYSDEE 350
            FS D+K+ SD +
Sbjct: 499 -FSMDTKLPSDRD 534
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|11230780|ref|NP_068684.1| tumor susceptibility gene
101 protein [Mus musculus]
         (391 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

12661                                                                  32   0.56 
30783                                                                  30   1.8  
30488                                                                  27   9.6  
>12661
          Length = 484

 Score = 31.6 bits (70), Expect = 0.56,   Method: Compositional matrix adjust.
 Identities = 12/45 (26%), Positives = 22/45 (48%)
 Frame = -3

Query: 66  NIYNIPICLWLLDTYPYNPPICFVKPTSSMTIKTGKHVDANGKIY 110
            + ++P+CLW    Y    P+C ++   S+ ++    V   GK Y
Sbjct: 380 GVRHVPLCLWHRSIYRRRSPLCQLRSVQSLFLREKMIVVRGGKTY 246
>30783
          Length = 765

 Score = 30.0 bits (66), Expect = 1.8,   Method: Compositional matrix adjust.
 Identities = 12/45 (26%), Positives = 22/45 (48%)
 Frame = +3

Query: 66  NIYNIPICLWLLDTYPYNPPICFVKPTSSMTIKTGKHVDANGKIY 110
            + ++P+CLW    Y    P+C ++   S+ ++    V   GK Y
Sbjct: 480 GVKHVPLCLWHRSIYRRCSPLCQLRSVQSLFLREKVIVVRGGKTY 614
>30488
          Length = 774

 Score = 27.3 bits (59), Expect = 9.6,   Method: Compositional matrix adjust.
 Identities = 15/31 (48%), Positives = 21/31 (67%)
 Frame = +3

Query: 304 EKMENQSENNDIDEVIIPTAPLYKQILNLYA 334
           EKM N+S + +IDE I   + LYKQ+ +LY 
Sbjct: 285 EKMYNESRSKNIDEHI---SILYKQVHDLYT 368
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6755448|ref|NP_035472.1| SEC22 vesicle trafficking
protein-like 1 [Mus musculus]
         (215 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

02964                                                                  30   0.56 
04498                                                                  28   3.0  
07853                                                                  28   3.3  
>02964
          Length = 832

 Score = 30.4 bits (67), Expect = 0.56,   Method: Compositional matrix adjust.
 Identities = 15/63 (23%), Positives = 32/63 (50%)
 Frame = -3

Query: 99  HGKKVPTVSRPYSFIEFDTFIQKTKKLYIDSRARRNLGSINTELQDVQRIMVANIEEVLQ 158
           HG     + R ++F+      Q+ K          N+  + +++ +V+ +M  NIE+V++
Sbjct: 827 HGGGAGELDRDFNFV----LAQQMKNFS--KAGSDNVSKLQSQVNEVKGVMTQNIEKVME 666

Query: 159 RGE 161
           RG+
Sbjct: 665 RGD 657
>04498
          Length = 1353

 Score = 28.1 bits (61), Expect = 3.0,   Method: Compositional matrix adjust.
 Identities = 9/28 (32%), Positives = 21/28 (75%)
 Frame = +3

Query: 134 NLGSINTELQDVQRIMVANIEEVLQRGE 161
           N+  + +++ +V+ +M  NIE+V++RG+
Sbjct: 90  NVSKLQSQVNEVKGVMTQNIEKVMERGD 173
>07853
          Length = 1702

 Score = 27.7 bits (60), Expect = 3.3,   Method: Compositional matrix adjust.
 Identities = 28/106 (26%), Positives = 41/106 (38%), Gaps = 20/106 (18%)
 Frame = -1

Query: 2   VLLTMIARVAD-----GLPLAASMQE-----DEQSGRDLQQYQSQAKQLFRK-------- 43
           +L    AR+A      G  +AA+  E     D+Q  +  QQ+   +++L R         
Sbjct: 781 ILAQKTARMASHSSIRGQRVAATGAEGGDIGDDQQAKRQQQHHDTSRRLSRHSAFPRNHS 602

Query: 44  --LNEQSPTRCTLEAGAMTFHYIIEQGVCYLVLCEAAFPKKLAFAY 87
             L +    RC L +   TF        C   LC  A P  L +AY
Sbjct: 601 F*LAQLYKQRCVLFSRVCTFCVTDGSPACTSSLCAPAHPHTLVYAY 464
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|8393337|ref|NP_058553.1| exocyst complex component 7
[Mus musculus]
         (697 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

05480                                                                  33   0.56 
09330                                                                  29   5.4  
>05480
          Length = 847

 Score = 32.7 bits (73), Expect = 0.56,   Method: Compositional matrix adjust.
 Identities = 14/31 (45%), Positives = 18/31 (58%), Gaps = 5/31 (16%)
 Frame = -3

Query: 74  QENVEKTLS-----CLDHVISYYHVASDTEK 99
           Q N  KT+      C+DH + Y+HV SD EK
Sbjct: 485 QTNTNKTVKNIKQICVDHTVGYWHVHSDNEK 393
>09330
          Length = 434

 Score = 29.3 bits (64), Expect = 5.4,   Method: Composition-based stats.
 Identities = 13/31 (41%), Positives = 17/31 (54%), Gaps = 5/31 (16%)
 Frame = +1

Query: 71  QRLQENVEKTLS-----CLDHVISYYHVASD 96
           Q  Q N  KT+      C+DH + Y+HV SD
Sbjct: 340 QLRQTNTNKTVKNIKQICVDHTVGYWHVHSD 432
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|13385196|ref|NP_080012.1| tetratricopeptide repeat
domain 35 [Mus musculus]
         (297 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

11398                                                                  31   0.59 
15030                                                                  31   0.71 
>11398
          Length = 3234

 Score = 31.2 bits (69), Expect = 0.59,   Method: Compositional matrix adjust.
 Identities = 16/51 (31%), Positives = 30/51 (58%), Gaps = 3/51 (5%)
 Frame = -2

Query: 139  EAIRELNEYLEQF---VGDQEAWHELAELYINEHDYAKAAFCLEELMMTNP 186
            EA++ L +Y  Q    + D+E W+ L   ++NE     A +CL++ +++NP
Sbjct: 1706 EALKLLEKYSLQPKTELSDEEVWYRLFSRFVNE-----AVYCLQDGILSNP 1569
>15030
          Length = 1392

 Score = 30.8 bits (68), Expect = 0.71,   Method: Compositional matrix adjust.
 Identities = 14/34 (41%), Positives = 22/34 (64%)
 Frame = -2

Query: 258  SWAANQINRAYQFAGRSKKETKYSLKAVEDMLET 291
            SWA  +I R     GR  +E+KY+L+AVE ++ +
Sbjct: 1265 SWAPKEITRCLILMGR--EESKYNLEAVETLMRS 1170
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6755210|ref|NP_036005.1| proteasome 26S non-ATPase
subunit 13 [Mus musculus]
         (376 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

34933                                                                  32   0.60 
14659                                                                  30   2.2  
>34933
          Length = 843

 Score = 31.6 bits (70), Expect = 0.60,   Method: Compositional matrix adjust.
 Identities = 15/59 (25%), Positives = 32/59 (54%)
 Frame = +1

Query: 57  IKLYENFISEFEHRVNPLSLVEIILHVVRQMTDPNVALTFLEKTREKVKSSDEAVILCK 115
           I +Y N   +++   NPLS V + +++  Q +D  ++  ++     K +SSD++ + C 
Sbjct: 340 IPVYVNIYLKYQSSDNPLSPVYVNIYLKYQSSDSPLSPVYIVNIYLKYQSSDKSTVSCS 516
>14659
          Length = 1168

 Score = 29.6 bits (65), Expect = 2.2,   Method: Compositional matrix adjust.
 Identities = 15/32 (46%), Positives = 20/32 (62%)
 Frame = -1

Query: 36  QLTLEVLDFVQDPCFAQGDGLIKLYENFISEF 67
           + T E L FV  P  ++GDG+ KLY  F+S F
Sbjct: 226 ETTTEPLLFVFHPH-SRGDGIFKLYSPFLSHF 134
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|56744242|ref|NP_033807.2| adaptor protein complex
AP-1, gamma 1 subunit [Mus musculus]
         (825 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

02203                                                                  33   0.61 
01783                                                                  29   7.0  
>02203
          Length = 1671

 Score = 32.7 bits (73), Expect = 0.61,   Method: Compositional matrix adjust.
 Identities = 44/245 (17%), Positives = 102/245 (41%), Gaps = 31/245 (12%)
 Frame = +1

Query: 361 DVSIKRRAMELSFALVNGNNIRGMMKELLYFLDSCE-PEFKADCASGIFLAAEK----YA 415
           D SI+ RA++L + +V   N+  ++K+L+  +D  E   ++ +  S I +   +    + 
Sbjct: 1   DESIRLRALDLLYGMVTKKNLMEIVKKLMVHMDKAEGSHYRDELLSKIIVICSQSNYQFV 180

Query: 416 PSKRWHIDTIMRVLTTAGSYVRDDAVPNLIQLITNSVEMHAYTVQRLY-----KAILGDY 470
            +  W++  ++ +    G+         ++ +      +  + V ++        +L + 
Sbjct: 181 TNFEWYVSILVELTRMEGTRHGGMIAAQMLDVAIRVQAIRHFAVSQMAILLENSHLLANN 360

Query: 471 SQQ----PLVQVAAWCIGEYGDLLVSGQCEEEEPIQVTEDEVLDILESVLISNMSTSVTR 526
           SQ+     ++  AAW  GE+ + L       +EP Q         LE++L   +++    
Sbjct: 361 SQRNGICEVLYAAAWICGEFSEHL-------KEPQQT--------LEAMLRPKLTS--LP 489

Query: 527 GYALTAIMKLSTRFTCTVNR-----------------IKKVVSIYGSSIDVELQQRAVEY 569
           G+  +  ++   +  C V R                 +++ + ++  S D+E+Q+RA   
Sbjct: 490 GHIQSVFVQNLLKLYCKVVRRLEDEDDQEGINQVHTTLQEKLPVFVQSGDLEVQERACSM 669

Query: 570 NALFK 574
             L K
Sbjct: 670 LGLVK 684
>01783
          Length = 2800

 Score = 29.3 bits (64), Expect = 7.0,   Method: Compositional matrix adjust.
 Identities = 20/93 (21%), Positives = 43/93 (46%)
 Frame = +3

Query: 215 NEKLVPQLVRILKNLIMSGYSPEHDVSGISDPFLQVXXXXXXXXXXXNDDDSSEAMNDIL 274
            EKL+ QLV +L+ + +SG   +  ++G      +V               S++A  D+ 
Sbjct: 498 KEKLIQQLVPLLRVVALSGAGQQRGLTG------RVLHTLLLHSFFTETTASTDAPQDVS 659

Query: 275 AQVATNTETSKNVGNAILYETVLTIMDIKSESG 307
            Q++ +    ++V  +  Y  ++ ++ +K E G
Sbjct: 660 GQMSVHV---RSVFQSTFYRALMQLLSMKPERG 749
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|40254617|ref|NP_033169.2| stromal cell derived factor
2 [Mus musculus]
         (211 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

11210                                                                  30   0.63 
29581                                                                  29   1.1  
01926                                                                  27   7.4  
>11210
          Length = 1021

 Score = 30.0 bits (66), Expect = 0.63,   Method: Compositional matrix adjust.
 Identities = 16/56 (28%), Positives = 25/56 (44%)
 Frame = +3

Query: 109 TSPLSGNQEVSAFGEEGEGDYLDDWTVLCNGPYWVRDGEVRFKHSSTDVLLSVTGE 164
           +SPL  N  + +     +  Y   +   CNG   ++ G + F+     VLLSV G 
Sbjct: 336 SSPLC*NNXLCSLSHMNKLSYJSPFVPCCNGGLLLKTGVILFR-----VLLSVNGS 488
>29581
          Length = 1278

 Score = 29.3 bits (64), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 14/35 (40%), Positives = 22/35 (62%)
 Frame = -1

Query: 159  LSVTGEQYGRPISGQKEVHGMAQPSQNNYWKAMEG 193
            + +TGE+YG PISG +E++  AQ +   +  A  G
Sbjct: 1254 MRMTGERYGIPISGLREINIFAQSATPEHRTAPGG 1150
>01926
          Length = 798

 Score = 26.6 bits (57), Expect = 7.4,   Method: Compositional matrix adjust.
 Identities = 22/62 (35%), Positives = 29/62 (46%), Gaps = 6/62 (9%)
 Frame = +2

Query: 155 TDVLLSVTGEQYGRP------ISGQKEVHGMAQPSQNNYWKAMEGIFMKPSELLRAEVHH 208
           T +LLS T    G P      ISG+  +H    PSQ+  W+ + G    PS  L   +H 
Sbjct: 572 TGLLLSTT--PAGHPVSPLSQISGRSALH*AEPPSQSRDWR-ISGSGKPPSRQLGLSLHV 742

Query: 209 AE 210
           AE
Sbjct: 743 AE 748
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31324532|ref|NP_083821.1| hypothetical protein
LOC328092 [Mus musculus]
         (168 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

14264                                                                  30   0.64 
04367                                                                  29   1.2  
04002                                                                  28   2.7  
18014                                                                  27   5.3  
09339                                                                  26   7.8  
>14264
          Length = 1790

 Score = 29.6 bits (65), Expect = 0.64,   Method: Compositional matrix adjust.
 Identities = 17/37 (45%), Positives = 22/37 (59%), Gaps = 3/37 (8%)
 Frame = +1

Query: 8  AQARALLQ-QCLHARLQVRPADGDAAAQWV--EIRRG 41
          +Q R  ++ QC H+R  V P DGDA    +  EIRRG
Sbjct: 58 SQCRPFVECQCCHSRSPVVPRDGDAIYISITDEIRRG 168
>04367
          Length = 1657

 Score = 28.9 bits (63), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 10/29 (34%), Positives = 17/29 (58%)
 Frame = -2

Query: 54   TDLLPKMVNTLLNVKLSETETGKHVSILD 82
            TD LPK +   LN+ + +T+TG     ++
Sbjct: 1431 TDFLPKQIPVSLNIYICQTQTGNRCKCVN 1345
>04002
          Length = 1163

 Score = 27.7 bits (60), Expect = 2.7,   Method: Compositional matrix adjust.
 Identities = 11/30 (36%), Positives = 17/30 (56%)
 Frame = +3

Query: 80  ILDLPGDVLIIPQATLGGRVKGRSMQYHSN 109
           +LDLPG + + PQA +   +   S  +HS 
Sbjct: 255 LLDLPGQLQLCPQAFVSAHLSCCSFLHHST 344
>18014
          Length = 469

 Score = 26.6 bits (57), Expect = 5.3,   Method: Compositional matrix adjust.
 Identities = 20/54 (37%), Positives = 32/54 (59%), Gaps = 1/54 (1%)
 Frame = -2

Query: 43  VIYVCFFKGADTDL-LPKMVNTLLNVKLSETETGKHVSILDLPGDVLIIPQATL 95
           V+ +CF KGAD+   +P ++ TL   K++E +  KH+  L    +VLI+ Q  L
Sbjct: 390 VLLMCFSKGADSVWAVPAVIYTLTKTKINEID--KHMDRL----NVLILCQLQL 247
>09339
          Length = 1393

 Score = 26.2 bits (56), Expect = 7.8,   Method: Compositional matrix adjust.
 Identities = 15/52 (28%), Positives = 26/52 (50%)
 Frame = -3

Query: 60  MVNTLLNVKLSETETGKHVSILDLPGDVLIIPQATLGGRVKGRSMQYHSNSG 111
           ++N +L V+   T+     S   L    L+   A++ GRVKGR  +  ++ G
Sbjct: 521 VLNAVLQVRFDFTQRSSTSSYRRLTRHPLLXVAASVQGRVKGRPFEVGADRG 366
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|61656188|ref|NP_001013407.1| MRS2 magnesium
homeostasis factor homolog [Mus musculus]
         (479 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

11398                                                                  32   0.67 
14946                                                                  30   2.0  
>11398
          Length = 3234

 Score = 31.6 bits (70), Expect = 0.67,   Method: Compositional matrix adjust.
 Identities = 31/116 (26%), Positives = 44/116 (37%), Gaps = 1/116 (0%)
 Frame = -2

Query: 313  HVFEKSSTGIDHAEEMELLLENY-YRLAEDLSNEARELRVLIDDSQSIIFINLDSHRNVM 371
            +V+EK+S G    EE   LLE Y  +   +LS+E    R+        ++          
Sbjct: 1748 YVYEKNSKGRTENEEALKLLEKYSLQPKTELSDEEVWYRLFSRFVNEAVYC--------- 1596

Query: 372  MRLNLQLTMGTFSLSLFGLMGVAFGMNLESSLEEDHRVFWLVTGIMFMGSGLIWRR 427
                  L  G  S  + G +G  FG+   S    DH V W  T +     G  WR 
Sbjct: 1595 ------LQDGILSNPVDGDIGAVFGLGFPSIFMGDHSVTWTCTEL-----GHWWRE 1461
>14946
          Length = 1599

 Score = 30.0 bits (66), Expect = 2.0,   Method: Compositional matrix adjust.
 Identities = 17/47 (36%), Positives = 25/47 (53%)
 Frame = -3

Query: 203  LPSQLAGEGQLVTYPLPFEFRAIEALLQYWISTLRGRLSVLQPLILE 249
            L +       LVTY L    +A+E    + + +  G+LSVLQPL L+
Sbjct: 1510 LDADFTAPNNLVTYTLAGNSKALE---YFQVGSSSGQLSVLQPLYLD 1379
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|225007605|ref|NP_803178.2| oral-facial-digital
syndrome 1 gene homolog [Mus musculus]
         (1019 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

19746                                                                  33   0.68 
02521                                                                  30   6.1  
>19746
          Length = 446

 Score = 32.7 bits (73), Expect = 0.68,   Method: Composition-based stats.
 Identities = 14/37 (37%), Positives = 24/37 (64%)
 Frame = -3

Query: 49  LMHPVLSGEVKPPSISVEGSALLIGASNSLVADHLQR 85
           L+H V+ G    P+++ +GSALLI A  + +  H++R
Sbjct: 198 LLHDVIQGTC*RPTVTNQGSALLISAKRARLIGHVER 88
>02521
          Length = 1487

 Score = 29.6 bits (65), Expect = 6.1,   Method: Compositional matrix adjust.
 Identities = 26/78 (33%), Positives = 40/78 (51%), Gaps = 7/78 (8%)
 Frame = -2

Query: 486  KELQKTEKAMELEHKDFETHRQALEKQLQSEIENSAQLRTQI-------AEYDASVKRLT 538
            KEL  T + M+ +       R  +EK+  S   + A L+T++       +E D +V  L 
Sbjct: 1381 KELSMTLEGMQADFHSVSEKRLVMEKRAISLNVDVADLQTKLNQIQNSASEKDNAVTELR 1202

Query: 539  VQVAELKSQLKQTQIALE 556
             QVA L SQL++T  +LE
Sbjct: 1201 GQVASLTSQLEKTSQSLE 1148
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|13384788|ref|NP_084524.1| CDK5 regulatory subunit
associated protein 3 [Mus musculus]
         (503 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

32718                                                                  32   0.69 
>32718
          Length = 427

 Score = 31.6 bits (70), Expect = 0.69,   Method: Composition-based stats.
 Identities = 15/41 (36%), Positives = 26/41 (63%), Gaps = 4/41 (9%)
 Frame = -3

Query: 392 KEKMLSLVSTLQQLIGRLT----SLRMQHLFMILASPRYVD 428
           ++K+L++V+T  Q++ R+     S+  QHLF I    R+VD
Sbjct: 398 RKKLLTVVTTTCQILNRMVVRXPSIESQHLFAISLCSRFVD 276
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|165932331|ref|NP_079650.3| glyoxalase 1 [Mus
musculus]
         (184 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

08299                                                                  30   0.69 
04308                                                                  27   3.6  
22708                                                                  27   3.9  
27118                                                                  27   4.2  
09175                                                                  26   8.5  
>08299
          Length = 917

 Score = 29.6 bits (65), Expect = 0.69,   Method: Compositional matrix adjust.
 Identities = 15/38 (39%), Positives = 21/38 (55%), Gaps = 2/38 (5%)
 Frame = -3

Query: 116 HNGNSDPRGFGHIGIAVPDVYSAC--KRFEELGVKFVK 151
           H  +S+PR  G  G  V D++S C   R +E+  K VK
Sbjct: 216 HATDSEPRAGGREGSKVKDIHSCCSFNRMKEINXKNVK 103
>04308
          Length = 1078

 Score = 27.3 bits (59), Expect = 3.6,   Method: Compositional matrix adjust.
 Identities = 14/38 (36%), Positives = 21/38 (55%), Gaps = 2/38 (5%)
 Frame = +2

Query: 116 HNGNSDPRGFGHIGIAVPDVYSACK--RFEELGVKFVK 151
           H  +S+PR  G     V D++S C+  R +E+  K VK
Sbjct: 941 HATDSEPRXGGRESSKVKDIHSCCRFNRMKEINQKNVK 1054
>22708
          Length = 337

 Score = 27.3 bits (59), Expect = 3.9,   Method: Compositional matrix adjust.
 Identities = 13/38 (34%), Positives = 20/38 (52%), Gaps = 2/38 (5%)
 Frame = +3

Query: 116 HNGNSDPRGFGHIGIAVPDVYSAC--KRFEELGVKFVK 151
           H  +S+PR  G     + D++S C   R +E+  K VK
Sbjct: 93  HATDSEPRAGGRESSKIKDIHSCCSFNRMKEINQKHVK 206
>27118
          Length = 420

 Score = 26.9 bits (58), Expect = 4.2,   Method: Compositional matrix adjust.
 Identities = 14/61 (22%), Positives = 25/61 (40%)
 Frame = +2

Query: 55  LTLLQKLDFPAMKFSLYFLAYEDKNDIPKDKSEKTAWTFSRKATLELTHNWGTEDDETQS 114
           +TL   LD   ++              P+ +SEK AW    +    +TH+W    D+ + 
Sbjct: 137 ITLQSALDVEGLELDTLLRC-------PEMRSEKCAWIHKDEGKKSITHHWQRTADQCRR 295

Query: 115 Y 115
           +
Sbjct: 296 H 298
>09175
          Length = 1786

 Score = 26.2 bits (56), Expect = 8.5,   Method: Compositional matrix adjust.
 Identities = 12/45 (26%), Positives = 26/45 (57%)
 Frame = -1

Query: 27   TKDFLLQQTMLRIKDPKKSLDFYTRVLGLTLLQKLDFPAMKFSLY 71
            T D L  Q    + +PK +L+++T+ +GL   + + FP+ +  ++
Sbjct: 1216 TYDLLCIQIYSDLPNPKMNLEYFTKKVGLFFRKHVYFPSHEJCIF 1082
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|10946822|ref|NP_067421.1| hypothetical protein
LOC58520 [Mus musculus]
         (140 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

05367                                                                  29   0.70 
10981                                                                  27   2.4  
>05367
          Length = 489

 Score = 28.9 bits (63), Expect = 0.70,   Method: Compositional matrix adjust.
 Identities = 15/37 (40%), Positives = 21/37 (56%)
 Frame = -3

Query: 82  WTFLLALGHFLSELFVFGTAAPTVGVLAPLMVASFSI 118
           W F L LGHF+S +FV       V + +P +V + SI
Sbjct: 448 WFFFLNLGHFISNMFV*SLVYLAVFLSSPFLVLTISI 338
>10981
          Length = 1878

 Score = 27.3 bits (59), Expect = 2.4,   Method: Composition-based stats.
 Identities = 13/56 (23%), Positives = 29/56 (51%)
 Frame = +3

Query: 20   MGNTLQSFRDHTFLYEKLYTGKPNLVNGLQARTFGIWTLLSSVIRCLCAIDIHNKT 75
            M N+ Q  +D+  +Y+   T   N+ +  + +  G+W  L++++ C  +   H K+
Sbjct: 1200 MPNSFQQNKDNIIMYQIHVTENVNM-HRCRHKLNGLWHCLAAILNCFHSNGYHEKS 1364
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31560071|ref|NP_082956.2| huntingtin-interacting
protein-1 protein interactor [Mus musculus]
         (429 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

06533                                                                  32   0.71 
24326                                                                  31   1.2  
10032                                                                  30   2.4  
>06533
          Length = 1102

 Score = 31.6 bits (70), Expect = 0.71,   Method: Compositional matrix adjust.
 Identities = 10/34 (29%), Positives = 23/34 (67%)
 Frame = -1

Query: 241 LEVERVLPQLKVTIRTDNKDWRIHVDQMHQHKSG 274
            +V++VLP+ +  +R+  ++W+ H  Q  ++K+G
Sbjct: 637 FQVKQVLPEDRFEVRSGGREWKFHFPQTTKNKNG 536
>24326
          Length = 1186

 Score = 30.8 bits (68), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 13/43 (30%), Positives = 20/43 (46%)
 Frame = +1

Query: 85  YMFCTLAAWLINKTGRAFEQPQEYDDPNATISNILSELRSFGR 127
           + F   A   +NK  R F  P +  DP A + ++ + L   GR
Sbjct: 262 HSFNXFAVVRVNKVARVFNDPXDVSDPRAGVVSVFAFLGCSGR 390
>10032
          Length = 836

 Score = 29.6 bits (65), Expect = 2.4,   Method: Compositional matrix adjust.
 Identities = 14/33 (42%), Positives = 20/33 (60%)
 Frame = +2

Query: 396 VVEHTLLQSKLKEKCNMTRDMHAAVTPESAIGF 428
           VVEH LLQ KLK+K    + +H + + +   GF
Sbjct: 2   VVEHVLLQGKLKDKTTQNKQVHGSTSND---GF 91
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6679201|ref|NP_032802.1| platelet-activating factor
acetylhydrolase, isoform Ib, gamma subunit [Mus musculus]
         (232 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

17895                                                                  30   0.71 
03156                                                                  28   4.1  
01327                                                                  28   4.2  
>17895
          Length = 1093

 Score = 30.4 bits (67), Expect = 0.71,   Method: Compositional matrix adjust.
 Identities = 18/65 (27%), Positives = 30/65 (46%)
 Frame = +1

Query: 71  FGIGGDSTQHVLWRLENGELEHIRPKIVVVWVGTNNHSHTAEQVTGGIKAIVQLVNKLQP 130
           FGIG +ST H   +LE G+++     +V    G N H+     +T     +  L+  ++P
Sbjct: 376 FGIGSESTHHFSGQLEKGKMDQFPSCLVFDKGGQNIHTQHPGVLTA---VLFNLLKSVRP 546

Query: 131 QARVV 135
             R  
Sbjct: 547 GFRTF 561
>03156
          Length = 1014

 Score = 27.7 bits (60), Expect = 4.1,   Method: Compositional matrix adjust.
 Identities = 19/87 (21%), Positives = 38/87 (43%), Gaps = 10/87 (11%)
 Frame = +1

Query: 16  QDVQGDGRWMSLHHRFVADSKDKEPEVV----------FIGDSLVQLMHQCEIWRELFSP 65
           Q++  D +W+   H  +   +DKE  +           F     +Q+   C++  +    
Sbjct: 307 QNLVTDVKWLPGSHLIIQAGEDKEVRIYDSRTLGIVRSFTKKQYIQM--SCDVTADGQFC 480

Query: 66  LHALNFGIGGDSTQHVLWRLENGELEH 92
           L   N G GG+  +  LW+L +G +++
Sbjct: 481 LTCSN-GFGGNGCEATLWQLSDGSIQN 558
>01327
          Length = 2215

 Score = 27.7 bits (60), Expect = 4.2,   Method: Compositional matrix adjust.
 Identities = 19/87 (21%), Positives = 38/87 (43%), Gaps = 10/87 (11%)
 Frame = +3

Query: 16  QDVQGDGRWMSLHHRFVADSKDKEPEVV----------FIGDSLVQLMHQCEIWRELFSP 65
           Q++  D +W+   H  +   +DKE  +           F     +Q+   C++  +    
Sbjct: 417 QNLVTDVKWLPGSHLIIQAGEDKEVRIYDSRTLGIVRSFTKKQYIQM--SCDVTADGQFC 590

Query: 66  LHALNFGIGGDSTQHVLWRLENGELEH 92
           L   N G GG+  +  LW+L +G +++
Sbjct: 591 LTCSN-GFGGNGCEATLWQLSDGSIQN 668
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|110625811|ref|NP_082723.2| proline-rich coiled-coil 1
[Mus musculus]
         (443 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

08514                                                                  32   0.72 
>08514
          Length = 1605

 Score = 31.6 bits (70), Expect = 0.72,   Method: Compositional matrix adjust.
 Identities = 33/132 (25%), Positives = 52/132 (39%), Gaps = 4/132 (3%)
 Frame = +1

Query: 232 KHSVESMITTLDPGMAPYIKSGGELDIVVTSNKEVKVAAVRDAFQEVFGLAVVVGEAGQS 291
           KH   S++   D   A   ++G  L     SN + K+  + D   +VFG+  V       
Sbjct: 253 KHRAHSVVILTDV-RADVSENGAHLIFSKFSNFQ-KIKGIHDVAFDVFGVVFV---PDHH 417

Query: 292 NIAP----QPVGYAAGLKGAQERIDSLRRSGAIHEKQTAVSVENFIAELLPDKWFDIGCL 347
           N+ P    QPV    G+    +   SL              +E F+   LPD+      L
Sbjct: 418 NLIPLENPQPVLQKDGVHAFNDSYHSL-------------IIERFVVGTLPDRVLSKTSL 558

Query: 348 VVEDPVHGIRLE 359
           +  DP+H + +E
Sbjct: 559 IALDPLHHVVVE 594
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|12025542|ref|NP_062626.1| arsA arsenite transporter,
ATP-binding, homolog 1 [Mus musculus]
         (348 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

27545                                                                  31   0.72 
10525                                                                  28   6.8  
>27545
          Length = 1318

 Score = 31.2 bits (69), Expect = 0.72,   Method: Compositional matrix adjust.
 Identities = 14/40 (35%), Positives = 21/40 (52%)
 Frame = +1

Query: 249 IAEFLSLYETERLIQELAKCKIDTHNIIVNQLVFPDPEKP 288
           +  FL+     + ++E  +C I   NIIV Q  F  P+KP
Sbjct: 145 VGGFLTQLVKGKPVEECVRCGIYVGNIIVQQAGFTLPDKP 264
>10525
          Length = 573

 Score = 27.7 bits (60), Expect = 6.8,   Method: Compositional matrix adjust.
 Identities = 11/28 (39%), Positives = 17/28 (60%)
 Frame = -3

Query: 229 IRSVSEQFKDPEQTTFICVCIAEFLSLY 256
           +RSV  QF   +Q   +CVC++E +  Y
Sbjct: 244 VRSVCVQFVYVKQCLILCVCVSECIHAY 161
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|161484625|ref|NP_031698.2| cerebellar
degeneration-related 2 [Mus musculus]
         (455 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

31579                                                                  32   0.74 
00596                                                                  31   0.83 
26305                                                                  30   2.2  
02220                                                                  29   3.2  
35978                                                                  28   5.3  
>31579
          Length = 1068

 Score = 31.6 bits (70), Expect = 0.74,   Method: Compositional matrix adjust.
 Identities = 31/109 (28%), Positives = 46/109 (42%), Gaps = 14/109 (12%)
 Frame = -2

Query: 343 SLLHEVDTQYSALKVKYEELL-KKCQQEQDS-----------LSHKAVQT--SRLLTRDL 388
           S+L E++TQY +L  KYE L+  K  Q   +           L HK VQT     L RD 
Sbjct: 662 SILDELETQYKSLFSKYESLMSSKINQTMQTDREEERAMRRRLQHKEVQTLLHETLNRDY 483

Query: 389 TGLVTQSEAGASGWXXXXXXXXXXXXXXXXXXXYKALFKEIFSCIKKTK 437
           +   TQ                           Y+ALF+++F+ ++KT+
Sbjct: 482 SSKDTQPPP------------------------YRALFQDLFATLRKTR 408
>00596
          Length = 1051

 Score = 31.2 bits (69), Expect = 0.83,   Method: Compositional matrix adjust.
 Identities = 13/35 (37%), Positives = 25/35 (71%)
 Frame = +3

Query: 258 QMLQAEHPFVNGVEKLVPDSLFVPFKEPSQSLLEE 292
            +++ +H FV  ++ ++PD + VPFKEP +S+L+ 
Sbjct: 201 NLIENKHRFVLVLDNVLPD-IVVPFKEPLRSILQN 302
>26305
          Length = 408

 Score = 30.0 bits (66), Expect = 2.2,   Method: Compositional matrix adjust.
 Identities = 21/60 (35%), Positives = 32/60 (53%), Gaps = 1/60 (1%)
 Frame = +3

Query: 276 DSLFVPFKEPSQS-LLEEMFLAAPEAPRKPLKRSSSETALSSLAGDDIVKDHEDTCIRRA 334
           +S F+  + PS S  LEE+ +     PR  L+R ++ T L+     D++   E TC RRA
Sbjct: 75  ESWFLESRSPSPSPTLEELGIT----PRSTLRREATSTPLTPSLEPDLLMKMETTCSRRA 242
>02220
          Length = 1269

 Score = 29.3 bits (64), Expect = 3.2,   Method: Compositional matrix adjust.
 Identities = 16/37 (43%), Positives = 19/37 (51%), Gaps = 3/37 (8%)
 Frame = -2

Query: 122  QTNIDHLQSQVEELKSS---SQGRGRQKACDQEKPAP 155
            QTNIDHL +  E L  S   S  RG + A  +  P P
Sbjct: 1034 QTNIDHLSTSAERLSISNGDSNTRGDKAASLRHSPTP 924
>35978
          Length = 711

 Score = 28.5 bits (62), Expect = 5.3,   Method: Compositional matrix adjust.
 Identities = 25/100 (25%), Positives = 52/100 (52%), Gaps = 4/100 (4%)
 Frame = +1

Query: 37  LLDRNTELEDSLQQMYTTNQEQLQEIEYLTKQVELLR----QMNEQHAKVYEQLDVTARE 92
           L+ R  ++ED+   ++    EQ  EIE L +Q+E ++    +  EQ  ++ +Q  V  ++
Sbjct: 244 LVTRFIDVEDTNFALFNYVNEQNNEIEKLNEQIEGIKNDIEKFKEQGIELEDQRQVILKQ 423

Query: 93  LEETNQKLVAESKASQQKILSLTETIECLQTNIDHLQSQV 132
           LE      + E+   +QK   + + ++ L+  ID L +++
Sbjct: 424 LEVKQTSALKEADDYEQKHKEVAKILDQLKAGIDSLFNKI 543
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|26986577|ref|NP_758479.1| TRAF type zinc finger
domain containing 1 [Mus musculus]
         (576 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

03990                                                                  32   0.74 
26077                                                                  32   1.0  
21557                                                                  30   3.4  
13824                                                                  29   5.3  
>03990
          Length = 1235

 Score = 32.0 bits (71), Expect = 0.74,   Method: Compositional matrix adjust.
 Identities = 31/105 (29%), Positives = 46/105 (43%), Gaps = 8/105 (7%)
 Frame = -3

Query: 38  VCPVCKEPFPK-SDMDIHMAAEHCQVTCKCN----KKLEKRQLKQHAETECPLRLAVCQH 92
           +C VC + F K S +  H +    Q + KC+      L    LK H  T   LRL VC  
Sbjct: 693 LCNVCNKGFTKPSKLKFHQSIHSGQKSFKCDVCNQTFLRASNLKAHKLTHTGLRLYVCDV 514

Query: 93  CDLELS-VVKLKEHE-DYCGARTELCGSCGRNVL-VKELKTHPEV 134
           C    +    LK H+  + G +  +C  C ++ +   +LK H  V
Sbjct: 513 CAKHFTRSTDLKRHKLIHTGEKMFVCDVCNKSFIHSADLKRHKLV 379
>26077
          Length = 421

 Score = 31.6 bits (70), Expect = 1.0,   Method: Composition-based stats.
 Identities = 21/72 (29%), Positives = 34/72 (47%), Gaps = 8/72 (11%)
 Frame = -1

Query: 30  IHCQRNIGVCPVCKEPFPKSDMDIHMA-------AEHCQVTCKCNKKL-EKRQLKQHAET 81
           +H  +    C +C+E F +S    H++        E C V   C+K   +  QLKQH ++
Sbjct: 412 LHTGKKPFTCDICQESFTQS---AHLSRHKLLHIGEKCFVCEVCDKAFTQPDQLKQHQQS 242

Query: 82  ECPLRLAVCQHC 93
              ++  VCQ C
Sbjct: 241 HTDIKPCVCQLC 206
>21557
          Length = 1167

 Score = 29.6 bits (65), Expect = 3.4,   Method: Compositional matrix adjust.
 Identities = 17/53 (32%), Positives = 24/53 (45%)
 Frame = +2

Query: 302 EELLIDHQTSCNPSHALRSLNTGSSSVRGMEDPGTIFQNFLQQATSNQFDTLM 354
           E   +DH    N     R L     S + M  PG +F+ F   A +NQFD ++
Sbjct: 242 EHYCVDHSQDMNT--VARLLLQDGDSQKQMSIPGVVFRQFAPSAATNQFDMVV 394
>13824
          Length = 566

 Score = 28.9 bits (63), Expect = 5.3,   Method: Compositional matrix adjust.
 Identities = 15/59 (25%), Positives = 22/59 (37%)
 Frame = +2

Query: 73  RQLKQHAETECPLRLAVCQHCDLELSVVKLKEHEDYCGARTELCGSCGRNVLVKELKTH 131
           R+       ECP R+  C HC  ++     K H   C      C  C R +   ++  H
Sbjct: 227 RKWTNTKTRECPQRMDKCDHCLTKMPFANKKNHIKECPKVPVPCPQCSRQIPRDKMNNH 403
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|145587080|ref|NP_001038978.2| Ras association
(RalGDS/AF-6) and pleckstrin homology domains 1 [Mus musculus]
         (679 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

10646                                                                  32   0.76 
09425                                                                  30   3.4  
>10646
          Length = 1562

 Score = 32.0 bits (71), Expect = 0.76,   Method: Compositional matrix adjust.
 Identities = 16/38 (42%), Positives = 22/38 (57%), Gaps = 1/38 (2%)
 Frame = -3

Query: 637  GTQLEESSKRTRVQFPAPSSGNSKPPI-TPAPKDPMSS 673
            G+ + E+S  TR   PAP+S  + PP+ TP P   M S
Sbjct: 1398 GSXVTEASPSTRCTRPAPTSTGANPPLCTPCPPSSMPS 1285
>09425
          Length = 1898

 Score = 30.0 bits (66), Expect = 3.4,   Method: Compositional matrix adjust.
 Identities = 18/60 (30%), Positives = 31/60 (51%)
 Frame = -3

Query: 476  SGIYYVPKGKAKVSRDLVCFLQLDHVNVYYGQDYRNKYKAPTDCCLALKHPQIQKKSQYI 535
             G+ Y+ + K KV++ L+   ++D  +    Q++   Y  P DCCL + H Q    S +I
Sbjct: 1287 GGVVYIIE-KDKVTKKLLK-TRMD*FSSTLDQNFLKLYFTPRDCCLCVIHHQCLSHSAFI 1114
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|85701951|ref|NP_001028613.1| expressed sequence
AU045404 [Mus musculus]
         (474 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

08205                                                                  32   0.77 
00896                                                                  31   0.96 
38085                                                                  29   3.3  
>08205
          Length = 397

 Score = 31.6 bits (70), Expect = 0.77,   Method: Composition-based stats.
 Identities = 13/34 (38%), Positives = 21/34 (61%)
 Frame = +1

Query: 59 DPMITTLPGLYLVSVGVVKPASWLLGWSEHVICS 92
          D ++T LP +   ++GVV P S   GW+ H +C+
Sbjct: 7  DILVTALPSIMGWALGVVGPVSVCCGWAGH*VCA 108
>00896
          Length = 2317

 Score = 31.2 bits (69), Expect = 0.96,   Method: Compositional matrix adjust.
 Identities = 12/25 (48%), Positives = 16/25 (64%)
 Frame = +1

Query: 173  RTSALLGFCGFMFRQTNIIWAAFCA 197
            R SALL  CG  FR+T ++W   C+
Sbjct: 1201 RQSALLNLCGITFRRTWMLWVQLCS 1275
>38085
          Length = 398

 Score = 29.3 bits (64), Expect = 3.3,   Method: Compositional matrix adjust.
 Identities = 13/33 (39%), Positives = 20/33 (60%)
 Frame = +3

Query: 410 PQKLLEFRYFILPYIIYRLNIPLPPISRLVCEL 442
           P     FRYF  P+++Y LNI +  I +L+C +
Sbjct: 201 PANSFHFRYFYWPFVVYSLNI-ICTIQKLICPV 296
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|46519171|ref|NP_777365.2| interphotoreceptor matrix
proteoglycan 2 [Mus musculus]
         (1243 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

27264                                                                  33   0.79 
03061                                                                  31   2.4  
14158                                                                  30   7.9  
>27264
          Length = 436

 Score = 33.1 bits (74), Expect = 0.79,   Method: Composition-based stats.
 Identities = 18/65 (27%), Positives = 26/65 (40%)
 Frame = +3

Query: 1040 KCYPGYLSVDELPCQSLCDLQPDFCLNDGKCDIMPGHGAICRCRVGSNWWYRGQHCEEFV 1099
            KC P       +P Q  CD         G+C I  G         G++WW+  QHC+   
Sbjct: 84   KCSPRLPHHRSIPNQVACD---------GRCHIDGG---------GTSWWHHWQHCDRTA 209

Query: 1100 SEPFV 1104
            +  F+
Sbjct: 210  ARSFL 224
>03061
          Length = 1003

 Score = 31.2 bits (69), Expect = 2.4,   Method: Composition-based stats.
 Identities = 16/40 (40%), Positives = 19/40 (47%), Gaps = 2/40 (5%)
 Frame = +3

Query: 1063 FCLN-DGK-CDIMPGHGAICRCRVGSNWWYRGQHCEEFVS 1100
            +CLN DG  C  +  HG  C C  G  WW+    C   VS
Sbjct: 753  YCLNCDGNACVYVCAHGCACVCDRGGGWWWLA*MCVYNVS 872
>14158
          Length = 668

 Score = 29.6 bits (65), Expect = 7.9,   Method: Composition-based stats.
 Identities = 27/87 (31%), Positives = 30/87 (34%), Gaps = 5/87 (5%)
 Frame = +3

Query: 1015 NPCKFQACNEFSECLVNP-WSGEAKCKC----YPGYLSVDELPCQSLCDLQPDFCLNDGK 1069
            N C   +C   S C VNP  S    C C    Y G L    +  +S  D     C N G 
Sbjct: 84   NACDNNSCANNSTCTVNPDVSRGYVCDCADSNYSGDLCNINIENKSCAD---GLCQNPGS 254

Query: 1070 CDIMPGHGAICRCRVGSNWWYRGQHCE 1096
            C         C C  G    Y G  CE
Sbjct: 255  CTDDVNASFTCACAPG----YTGSLCE 323
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|62530192|ref|NP_666240.4| discs, large
homolog-associated protein 4 isoform a [Mus musculus]
         (992 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

36618                                                                  33   0.79 
24449                                                                  30   4.2  
10557                                                                  30   4.2  
27713                                                                  30   5.0  
>36618
          Length = 157

 Score = 32.7 bits (73), Expect = 0.79,   Method: Composition-based stats.
 Identities = 17/35 (48%), Positives = 24/35 (68%), Gaps = 2/35 (5%)
 Frame = +2

Query: 834 LSEEVLGKVLSAVGSAQLLMSQ--KFQQFRGLCEQ 866
           L+EEV G++ + V  AQLLM +  KF QF GL ++
Sbjct: 2   LTEEVEGQIRTTVCQAQLLMDKKGKFHQFAGLVDK 106
>24449
          Length = 645

 Score = 30.0 bits (66), Expect = 4.2,   Method: Composition-based stats.
 Identities = 11/19 (57%), Positives = 15/19 (78%)
 Frame = +3

Query: 885 WDLLQLSIEDISMKFDELY 903
           WD L LS++ IS+ FD+LY
Sbjct: 492 WDYLSLSLQKISVHFDQLY 548
>10557
          Length = 1102

 Score = 30.0 bits (66), Expect = 4.2,   Method: Composition-based stats.
 Identities = 11/19 (57%), Positives = 15/19 (78%)
 Frame = +3

Query: 885 WDLLQLSIEDISMKFDELY 903
           WD L LS++ IS+ FD+LY
Sbjct: 156 WDYLSLSLQKISVHFDQLY 212
>27713
          Length = 829

 Score = 30.0 bits (66), Expect = 5.0,   Method: Composition-based stats.
 Identities = 18/45 (40%), Positives = 25/45 (55%), Gaps = 2/45 (4%)
 Frame = +3

Query: 638 KHAALKSEQGTLTSSESHS--EAIPKRKLSSIGIQVDCIQPVPKE 680
           KH    S   T+T+S SHS  +  P+R   S G+  DCI  +PK+
Sbjct: 633 KHDLCFSLFSTITTSRSHSCDKGCPERG-KSYGVDFDCILELPKQ 764
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|169790912|ref|NP_663492.3| ORM1-like 1 [Mus musculus]
         (153 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

07311                                                                  29   0.81 
11181                                                                  28   1.2  
19807                                                                  27   3.9  
26269                                                                  26   6.9  
01496                                                                  25   9.2  
>07311
          Length = 2662

 Score = 28.9 bits (63), Expect = 0.81,   Method: Compositional matrix adjust.
 Identities = 14/46 (30%), Positives = 24/46 (52%)
 Frame = +1

Query: 68   KGTPFETPDQGRARLLTHWEQLDYGVQFTSSRKFFTISPIILYFLA 113
            +G+P    + GRA    HW++ +   + ++     TIS I +YF A
Sbjct: 1513 RGSPHTASETGRAGSPEHWDRKESESRLSNPL*HQTISSIWMYFFA 1650
>11181
          Length = 681

 Score = 28.5 bits (62), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 21/63 (33%), Positives = 29/63 (46%), Gaps = 13/63 (20%)
 Frame = -2

Query: 31  GLLHIVL--LSIPFCSV-----PVAWTLTNIIHNLGMYVF------LHAVKGTPFETPDQ 77
           G+LHI+L  L +  CSV      V WT+ N   NL +Y++       H   G   +TP  
Sbjct: 431 GVLHILLWGLFLSLCSVLVCPRAVGWTVNNTKLNLKLYIYHNVHLNSHQHDGAVVQTPAS 252

Query: 78  GRA 80
           G  
Sbjct: 251 GSG 243
>19807
          Length = 858

 Score = 26.6 bits (57), Expect = 3.9,   Method: Compositional matrix adjust.
 Identities = 11/25 (44%), Positives = 18/25 (72%)
 Frame = -1

Query: 112 LASFYTKYDPTHFILNTASLLSVLI 136
           L  F  +Y PT +IL+T++LLS+ +
Sbjct: 195 LWEFRGRYSPTSWILSTSALLSLAV 121
>26269
          Length = 679

 Score = 25.8 bits (55), Expect = 6.9,   Method: Compositional matrix adjust.
 Identities = 15/47 (31%), Positives = 20/47 (42%)
 Frame = +3

Query: 41  PFCSVPVAWTLTNIIHNLGMYVFLHAVKGTPFETPDQGRARLLTHWE 87
           P   +PV W   N  H+LG+ +F H         PD     L  HW+
Sbjct: 255 PLICLPVIWLELNFDHHLGLDLFDHLPS-----FPDHQPHCLTXHWD 380
>01496
          Length = 1447

 Score = 25.4 bits (54), Expect = 9.2,   Method: Compositional matrix adjust.
 Identities = 22/80 (27%), Positives = 32/80 (40%), Gaps = 24/80 (30%)
 Frame = -3

Query: 32  LLHIVLLSIPFCSV---------PVAWTLTNIIHNLGMYVFLHAVKGTPFETPDQ----- 77
           LLH+VL   P C +         P    L+N+    G  +FL  + G P + P+      
Sbjct: 536 LLHLVLCQKPLCPMQVLSPHPT*PTEIPLSNLNFASGRKIFLLLIWGLP-KCPENDLLSF 360

Query: 78  ----------GRARLLTHWE 87
                     G+ RL +HWE
Sbjct: 359 VVLQA*QNGPGKWRLHSHWE 300
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|23346595|ref|NP_694792.1| hypothetical protein
LOC224904 [Mus musculus]
         (119 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

21200                                                                  28   0.81 
03928                                                                  25   6.9  
27195                                                                  25   9.5  
>21200
          Length = 405

 Score = 28.1 bits (61), Expect = 0.81,   Method: Compositional matrix adjust.
 Identities = 19/57 (33%), Positives = 25/57 (43%), Gaps = 7/57 (12%)
 Frame = -1

Query: 59  VCQQTGLEMPQLPTPPKIKFPNFRDS-------WNSGIISVMSALSVAPSKAREYSK 108
            C+ TG EMP   TPP  K    R S        +S I SV + LS   + +R   +
Sbjct: 405 TCKHTGTEMPPKRTPPNTKKRASRPSGSPSHGEHDSMIDSVCNTLSGQETDSRRRER 235
>03928
          Length = 523

 Score = 25.0 bits (53), Expect = 6.9,   Method: Compositional matrix adjust.
 Identities = 17/77 (22%), Positives = 32/77 (41%), Gaps = 1/77 (1%)
 Frame = -1

Query: 15  GSVAGGA-VYLVYDQELLGPSDKSEAALRKAEEVVPPAMYQFSQYVCQQTGLEMPQLPTP 73
            +V+ GA +     QE     D +++      +  PPA       + +Q  +EM     P
Sbjct: 508 STVSNGAEIKEDASQESTASRDSTQSEASSVSQSDPPAKSNEPPQLVKQEPMEMEDPSAP 329

Query: 74  PKIKFPNFRDSWNSGII 90
            +++FP  R+     I+
Sbjct: 328 IRVRFPTPRNQSKEAIV 278
>27195
          Length = 1348

 Score = 24.6 bits (52), Expect = 9.5,   Method: Composition-based stats.
 Identities = 13/52 (25%), Positives = 22/52 (42%)
 Frame = -3

Query: 58   YVCQQTGLEMPQLPTPPKIKFPNFRDSWNSGIISVMSALSVAPSKAREYSKE 109
            Y+  Q GL +   P PP  K+   R + N  +   +  + +       YSK+
Sbjct: 1028 YITSQKGLRLEGKPLPPPHKYGPLRQNGNKSMKRCLYFIKIYVCA*SYYSKQ 873
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|37620185|ref|NP_851833.2| Bardet-Biedl syndrome 9
[Mus musculus]
         (880 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

30216                                                                  32   0.81 
>30216
          Length = 411

 Score = 32.3 bits (72), Expect = 0.81,   Method: Compositional matrix adjust.
 Identities = 15/28 (53%), Positives = 21/28 (75%)
 Frame = +1

Query: 693 LDGTYKQVIALADAIEENQDRLLQSFSG 720
           LDGT KQV+A+ D +    D++LQSF+G
Sbjct: 253 LDGTVKQVLAMMDIV---LDQMLQSFNG 327
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|51829985|ref|XP_484535.1| PREDICTED: hypothetical
protein LOC209018 isoform 1 [Mus musculus]
         (1427 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

10203                                                                  33   0.83 
19243                                                                  33   0.96 
19949                                                                  32   1.3  
04871                                                                  32   1.5  
17602                                                                  31   3.1  
02147                                                                  31   3.9  
>10203
          Length = 2103

 Score = 33.1 bits (74), Expect = 0.83,   Method: Compositional matrix adjust.
 Identities = 26/95 (27%), Positives = 41/95 (43%)
 Frame = -2

Query: 1255 DYCSICLQQYKRRQEMADEIIVFSCGHLYHSFCLQSKECTLEVEGQTRWACHKCSSSNKA 1314
            D C+IC +  +  +++        CGHL+H+ CL+S      +E  T  +C  C  S   
Sbjct: 1115 DECAICWEGMEAARKLP-------CGHLFHNSCLRSW-----LEQDT--SCPTCRMSLSE 978

Query: 1315 GKLSENPSENKKGRITSSQVKMSPSYHQSKGDPPA 1349
               ++NPS N            +P    +  DPPA
Sbjct: 977  RPPNQNPSANPPN--------AAPVNPANIVDPPA 897
>19243
          Length = 416

 Score = 32.7 bits (73), Expect = 0.96,   Method: Compositional matrix adjust.
 Identities = 37/141 (26%), Positives = 58/141 (41%)
 Frame = -2

Query: 403 INFTWINSRTVVLLDSVEKLHVIDRQTQEELETMEISEVQLVYNSSHFKSLATGGNVSQA 462
           ++F  IN RT  +L S          +Q  L+T    +  L+Y S H + +    +   A
Sbjct: 409 VSFNKINXRTFDILFS----------SQSNLKTFIDEKTLLIYQSPH-EDICQREDT*YA 263

Query: 463 LALVGEKACYQSISSYGGQIFYLGTKSVYVMMLRSWRERMDHLLKQDCLTEALALAWSFH 522
           + L    A  ++          L    V + +L  WR  + H+L  D + EAL       
Sbjct: 262 IRLTKPFANEKTRDXLFSPHSLLAMPLVVIPVLFHWRPVVGHVLDGDGVQEALGFDLVLQ 83

Query: 523 EGKAKAVVGLSGDVSKRKAVV 543
              A+AVV L   V+ R A+V
Sbjct: 82  HADAEAVVVL---VAHRLALV 29
>19949
          Length = 903

 Score = 32.3 bits (72), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 40/154 (25%), Positives = 62/154 (40%), Gaps = 20/154 (12%)
 Frame = +2

Query: 195 GQYGAISALSINNDCSRLLCGFAKGQITMWDLASGKLLRSIT---DA------HP----- 240
           G  G +  L  + D   +      G + +WDL +GKLL  +    DA      HP     
Sbjct: 113 GHTGCVCCLRFSPDGRWIASASEDGLVKLWDLTAGKLLTDLKLHRDAVNTIEFHPHEFLL 292

Query: 241 -PGTAILHIKFTDDPTLAICNDS---GGSVFELTFKRVMGVRTCESRCLFSGSKG--EVC 294
             G+A   +KF D  T  + + +     S+  + F         +  CL+SGSK   +V 
Sbjct: 293 ASGSADRTVKFWDLETFQLISTTEPEANSIRSILFHP-------DGVCLYSGSKDTLKVY 451

Query: 295 CIEPLHSKPELKDHPITQFSLLAMASLTKILVIG 328
             EPL    EL D     +  +   S++   +IG
Sbjct: 452 HWEPL----ELYDTVSVPWGQVCDMSISNTQLIG 541
>04871
          Length = 1110

 Score = 32.3 bits (72), Expect = 1.5,   Method: Composition-based stats.
 Identities = 17/51 (33%), Positives = 30/51 (58%), Gaps = 1/51 (1%)
 Frame = -2

Query: 375 VHFLLVKRDESGAIHVTKQKHLHLYYDLINFTWI-NSRTVVLLDSVEKLHV 424
           +HFLL+K D   ++HV+K    H+Y D+    W+ +S +V +     ++HV
Sbjct: 995 LHFLLIKGDLKRSVHVSK----HVYMDVPGHVWLMHSLSVCIWSRSVRVHV 855
>17602
          Length = 481

 Score = 31.2 bits (69), Expect = 3.1,   Method: Composition-based stats.
 Identities = 29/99 (29%), Positives = 45/99 (45%), Gaps = 11/99 (11%)
 Frame = +3

Query: 200 ISALSINNDCSRLLCGFAKGQITMWDLASGKLLRS-ITDAHPPGTAILHIKF-------- 250
           ++A+  N D S ++     G   +WD ASG+ L + I D +PP   +  +KF        
Sbjct: 63  VTAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLXTLIDDDNPP---VSFVKFSPNGKYIL 233

Query: 251 --TDDPTLAICNDSGGSVFELTFKRVMGVRTCESRCLFS 287
             T D TL + + S G       K  +G R  E  C+F+
Sbjct: 234 AATLDNTLKLWDYSKGKC----LKTYVGHRN-EKYCIFA 335
>02147
          Length = 1547

 Score = 30.8 bits (68), Expect = 3.9,   Method: Compositional matrix adjust.
 Identities = 20/77 (25%), Positives = 35/77 (45%), Gaps = 2/77 (2%)
 Frame = +2

Query: 195 GQYGAISALSINNDCSRLLCGFAKGQITMWDLASGKLLRSITDAHPPGTAILHIKFTDDP 254
           G  GA+   ++N + +R   G A     +WD   G+ L++ +  H     +  + F+ D 
Sbjct: 167 GHKGAVWGATLNREATRAATGAADFSAKIWDAEKGEELQTFSHKH----IVKSVDFSHDG 334

Query: 255 T--LAICNDSGGSVFEL 269
           T  L   N+    VF+L
Sbjct: 335 TALLTGSNEKLLKVFDL 385
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|120953219|ref|NP_080414.2| hypothetical protein
LOC67412 [Mus musculus]
         (945 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

01964                                                                  32   0.87 
06045                                                                  30   3.6  
>01964
          Length = 2512

 Score = 32.3 bits (72), Expect = 0.87,   Method: Compositional matrix adjust.
 Identities = 33/121 (27%), Positives = 58/121 (47%), Gaps = 6/121 (4%)
 Frame = -3

Query: 633 MREQSESLSELRQH----LQLVEDETELLRR--NVADLEEQNKRITAELNKYKYKSSGHD 686
           + E  +SL E RQ     +Q +    EL+R+   V  L+E NK +  E       +    
Sbjct: 557 LEETKQSLGEERQQNQSSVQTMSQHMELMRKVETVNLLQESNKMLRDE-------NCSQK 399

Query: 687 SSRHHDNAKTEALQEELKAARLQINELSGKVMQLQYENRVLMSNMQRYDLASHLGIRGSP 746
           SS+H   AK   L++E+   +  + ELS +   L+ E + L + ++R+ L +H  +  S 
Sbjct: 398 SSQHEMEAKVRRLEDEISPLQASVRELSAQKEVLEVEKKTLTAEVERWKLRTHHLVEQSD 219

Query: 747 R 747
           +
Sbjct: 218 K 216
>06045
          Length = 1270

 Score = 30.4 bits (67), Expect = 3.6,   Method: Compositional matrix adjust.
 Identities = 42/139 (30%), Positives = 66/139 (47%), Gaps = 11/139 (7%)
 Frame = -3

Query: 438 DLKVAKDVSVRLHHELENVEEKRTTTEDENEKLRQQLIEVEI----AKQALQNEL--EKM 491
           D++  K+ + RL  EL +V E++   E    +L +Q  E       A+ ALQ++L   + 
Sbjct: 953 DIESLKEENARLQSELSSVREEKDELETSIGELDEQHEEATTHLISARNALQSQLADSQR 774

Query: 492 KELSLKR-----RGSKDLPKSEKKAQQTPTEDDNEDLKCQLQFVKEEAALMRKKMAKIDK 546
           + LSL+      R    LP      QQ       EDLK +LQ V++E A +R++ +  D 
Sbjct: 773 QVLSLQDELDQLRQQPALPDPSPALQQV------EDLKQELQTVQQEVASLRQQASSQDA 612

Query: 547 EKDRFEHELQKYRSFYGDL 565
           E    + +LQK      DL
Sbjct: 611 ELSELKTKLQKGTLALNDL 555
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|160333304|ref|NP_033822.2| apolipoprotein A-I [Mus
musculus]
         (264 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

15506                                                                  30   0.87 
19914                                                                  28   5.2  
19846                                                                  27   5.8  
21091                                                                  27   8.6  
>15506
          Length = 944

 Score = 30.4 bits (67), Expect = 0.87,   Method: Compositional matrix adjust.
 Identities = 18/46 (39%), Positives = 25/46 (54%)
 Frame = -2

Query: 185 QLAPHSEQMRESLAQRLAELKSNPTLNEYHTRAKTHLKTLGEKARP 230
           QL PHS     SL  RLA +K + +L+ YH       +T+G K+ P
Sbjct: 595 QLPPHSSP--SSLIMRLAMMKDSLSLDLYHLSTYFLSQTVGIKSYP 464
>19914
          Length = 852

 Score = 27.7 bits (60), Expect = 5.2,   Method: Compositional matrix adjust.
 Identities = 24/90 (26%), Positives = 43/90 (47%), Gaps = 9/90 (10%)
 Frame = +2

Query: 129 KKWKEDVELYRQKVAPLG---AELQESARQKLQELQGRLSPVAEE------FRDRMRTHV 179
           KK  ED     Q+V  L    AELQ    Q++ ++Q ++SP  EE      ++ R    +
Sbjct: 368 KKRSEDASQQTQEVQRLQNQMAELQSQYEQQIADVQSQISPCNEEGEHQCVYQQRQEEAL 547

Query: 180 DSLRTQLAPHSEQMRESLAQRLAELKSNPT 209
             ++ +       + ES +Q++A L+ + T
Sbjct: 548 GDMKARYEQRISDLEESFSQQIASLQHSDT 637
>19846
          Length = 663

 Score = 27.3 bits (59), Expect = 5.8,   Method: Compositional matrix adjust.
 Identities = 17/41 (41%), Positives = 26/41 (63%), Gaps = 4/41 (9%)
 Frame = +3

Query: 148 ELQESARQKLQELQGRLSPVAEEF----RDRMRTHVDSLRT 184
           +++ES   KLQ +Q RLS + +E+     DR+  HVDS+ T
Sbjct: 321 QMKESYNIKLQTVQDRLSALQQEYDNANDDRLH-HVDSINT 440
>21091
          Length = 792

 Score = 26.9 bits (58), Expect = 8.6,   Method: Compositional matrix adjust.
 Identities = 14/27 (51%), Positives = 19/27 (70%), Gaps = 2/27 (7%)
 Frame = -1

Query: 118 QKVQPYLDEFQKKWKE--DVELYRQKV 142
           + ++P L  F+K+ KE  DVELY QKV
Sbjct: 285 KNIKPTLAVFRKRLKERYDVELYNQKV 205
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|94369504|ref|XP_984131.1| PREDICTED: hypothetical
protein LOC229227 [Mus musculus]
         (1211 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

18219                                                                  33   0.87 
31736                                                                  31   2.6  
13833                                                                  30   6.2  
>18219
          Length = 476

 Score = 32.7 bits (73), Expect = 0.87,   Method: Composition-based stats.
 Identities = 16/55 (29%), Positives = 29/55 (52%), Gaps = 3/55 (5%)
 Frame = -3

Query: 636 KWRNV---TQEKAGWVECWTVPSVMLTIDYTWHPIYPQKADEQLKQSLSEMEETM 687
           KWR +   T  + GW+ CW+   +  T+D+ W       + E +K+SL+ +  T+
Sbjct: 279 KWRELRKKTGPRQGWI*CWSC--LTFTLDFLWLKPTLIHSSEIIKKSLTRLRTTL 121
>31736
          Length = 539

 Score = 31.2 bits (69), Expect = 2.6,   Method: Composition-based stats.
 Identities = 12/42 (28%), Positives = 23/42 (54%)
 Frame = +3

Query: 924 TAKVTAPQLACLLEWGQTFVFHVVCREYELERPKSVIVCQHG 965
           T +++ P + C+       +F VV   Y +E+P+ +I+C  G
Sbjct: 6   TRRLSVPTMTCVTASTLMNLFEVVMDVYNMEKPEGIILCMGG 131
>13833
          Length = 374

 Score = 30.0 bits (66), Expect = 6.2,   Method: Composition-based stats.
 Identities = 11/28 (39%), Positives = 19/28 (67%)
 Frame = +2

Query: 47  YNSRNVGLILTLVLNRLYKHGYIHIGSF 74
           +N++  G + T++LNRL+KH  +  G F
Sbjct: 170 HNTKRGGDVFTVILNRLHKHQLVSSGGF 253
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|21312988|ref|NP_083630.1| hypothetical protein
LOC72083 [Mus musculus]
         (159 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

03645                                                                  29   0.89 
>03645
          Length = 1155

 Score = 28.9 bits (63), Expect = 0.89,   Method: Compositional matrix adjust.
 Identities = 15/48 (31%), Positives = 27/48 (56%), Gaps = 3/48 (6%)
 Frame = -1

Query: 50  GAAIDPDVFKILVDLLNLNVAPLAVFQMLKSMCAGQRL---ASDPQDS 94
           G  +D D+F +  D+L+ N A  A   ++ ++C G+R+    +D  DS
Sbjct: 999 GFCLDRDMFWLYCDVLSKNGALKATKIVVSALCFGRRI*DRENDADDS 856
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|10946800|ref|NP_067408.1| syntaxin 6 [Mus musculus]
         (255 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

08192                                                                  30   0.91 
>08192
          Length = 768

 Score = 30.0 bits (66), Expect = 0.91,   Method: Compositional matrix adjust.
 Identities = 17/50 (34%), Positives = 28/50 (56%)
 Frame = +2

Query: 176 VSGSIGVLKNMSQRIGGELEEQAVMLDDFSHELESTQSRLDNVMKKLAKV 225
           VSG IG L+NM+  +G E+E Q   +D  + +  S   R+D   ++  K+
Sbjct: 332 VSGMIGNLRNMAVDMGNEIESQNRQIDRVNQKGVSLNDRVDVANQRAHKI 481
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|21703842|ref|NP_663397.1| hypothetical protein
LOC28088 [Mus musculus]
         (505 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

01886                                                                  31   0.91 
15043                                                                  30   1.5  
26926                                                                  28   9.2  
>01886
          Length = 3921

 Score = 31.2 bits (69), Expect = 0.91,   Method: Compositional matrix adjust.
 Identities = 22/66 (33%), Positives = 33/66 (50%)
 Frame = +1

Query: 232  QVVDEIFNEYAAKKMGIDHKGQVCVMIHSGSRGLGHQVATDALVAMEKAMKRDKIIVNDR 291
            QV DE   +  A  +G D    + ++IH    G      T  L+A+E+ ++R  + VNDR
Sbjct: 3019 QVNDE--GDVGAHAVGKDEVWVLLLLIHVNQVGR----HTHGLLALERDLQRVAVQVNDR 3180

Query: 292  QLACAR 297
             L C R
Sbjct: 3181 ILVCYR 3198
>15043
          Length = 973

 Score = 30.4 bits (67), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 14/44 (31%), Positives = 27/44 (61%)
 Frame = -1

Query: 448 VLDKLADMGIAIRVASPKLVMEEAPESYKNVTDVVNTCHDAGIS 491
           +L + +D  +AIR  SP L+    P+S++++   ++ C D G+S
Sbjct: 319 ILQESSDERLAIRNMSPYLL--GIPQSFQHIHHTLSPCQDLGVS 194
>26926
          Length = 819

 Score = 28.1 bits (61), Expect = 9.2,   Method: Compositional matrix adjust.
 Identities = 14/32 (43%), Positives = 18/32 (56%), Gaps = 2/32 (6%)
 Frame = -1

Query: 161 IPMNA--KDLEEALEMGVDWSLREGYAWAEDK 190
           +P+ A  KD    LE+GV W   E   W+EDK
Sbjct: 519 VPLGAWFKDRSPVLEVGVRWHREEARWWSEDK 424
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|18875424|ref|NP_573511.1| glomulin, FKBP associated
protein [Mus musculus]
         (596 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

35019                                                                  32   0.96 
00980                                                                  30   2.8  
>35019
          Length = 1971

 Score = 31.6 bits (70), Expect = 0.96,   Method: Compositional matrix adjust.
 Identities = 22/59 (37%), Positives = 32/59 (54%)
 Frame = -3

Query: 353 QYLEIKSFLAVPQGLVKVMTLCPIETLRKKGLSMLQLFIDKLDSQGKYTLFRCLLNTSN 411
           QY++     AVP+GLV V  LC    LRK    +L+LF+  L+     T+F  +L+  N
Sbjct: 490 QYMK-----AVPRGLVAVHLLCFSGILRKL---LLRLFVGSLNIAVSTTIFIRVLSDVN 338
>00980
          Length = 998

 Score = 30.0 bits (66), Expect = 2.8,   Method: Compositional matrix adjust.
 Identities = 12/34 (35%), Positives = 21/34 (61%)
 Frame = +1

Query: 200 NAKLKDELLKFCFKGLKCPLLTAQFLEQSEDVGN 233
           N K K +L+K CFK  + P + ++   Q++ +GN
Sbjct: 343 NHKSKSKLIKSCFKPSQVPWVISRLSPQTKHIGN 444
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|145976948|ref|NP_766148.2| centrobin, centrosomal
BRCA2 interacting protein [Mus musculus]
         (887 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

06755                                                                  32   0.99 
>06755
          Length = 892

 Score = 32.0 bits (71), Expect = 0.99,   Method: Composition-based stats.
 Identities = 14/35 (40%), Positives = 22/35 (62%)
 Frame = +1

Query: 726 PKAGSRAVSSWEEAPQVPRLPPPVHKTKVPLAMAS 760
           P++ SR  SSW+++ QVP  P PV+ + + L   S
Sbjct: 631 PESESRL*SSWKQSHQVPHYPVPVYSSPLSLCQHS 735
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|13384778|ref|NP_079672.1| 6-phosphogluconolactonase
[Mus musculus]
         (257 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

00946                                                                  30   1.0  
01174                                                                  28   4.7  
>00946
          Length = 1053

 Score = 30.0 bits (66), Expect = 1.0,   Method: Compositional matrix adjust.
 Identities = 14/34 (41%), Positives = 18/34 (52%)
 Frame = -1

Query: 104 PIPDSQVLTINPALPVEDAAEDYARKLRQALQGD 137
           P+P  Q L++NP  PV D  E  A  +R A  G 
Sbjct: 498 PLPRCQSLSLNPPTPVPDCLERSASSMRPAC*GQ 397
>01174
          Length = 3438

 Score = 27.7 bits (60), Expect = 4.7,   Method: Compositional matrix adjust.
 Identities = 17/39 (43%), Positives = 22/39 (56%)
 Frame = -3

Query: 1   MAAPAPSLISVFSSPQELGASLAQLVAQRAASCLEGDRG 39
           MAA  PSL+   SSP  +GAS  +     A++ LE D G
Sbjct: 667 MAASDPSLVDTGSSPWNVGASGTE---SEASTVLERDTG 560
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|14149756|ref|NP_080306.1| eukaryotic translation
initiation factor 2, subunit 2 (beta) [Mus musculus]
         (331 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

02783                                                                  30   1.0  
07779                                                                  30   1.8  
19809                                                                  28   6.1  
>02783
          Length = 873

 Score = 30.4 bits (67), Expect = 1.0,   Method: Compositional matrix adjust.
 Identities = 15/60 (25%), Positives = 25/60 (41%)
 Frame = -2

Query: 206 QVVRVGTKKTSFVNFTDICKLLHRQPKHLLAFLLAELGTSGSIDGNNQLVIKGRFQQKQI 265
            VV        + +    CK  H +  H  A + +E   S +I+  ++   K  +QQK I
Sbjct: 545 HVVHFACTYIYYKHVHKCCKYTHNECTHTRAHMQSEKTKSSNIENQSKTAFKSLYQQKYI 366
>07779
          Length = 1055

 Score = 29.6 bits (65), Expect = 1.8,   Method: Compositional matrix adjust.
 Identities = 10/25 (40%), Positives = 18/25 (72%)
 Frame = +1

Query: 170 RDYTYEELLNRVFNIMREKNPDMVA 194
           R   +++ L RV N+++EKNPD+ +
Sbjct: 784 RRLVFQQYLRRVINLLQEKNPDLCS 858
>19809
          Length = 553

 Score = 27.7 bits (60), Expect = 6.1,   Method: Compositional matrix adjust.
 Identities = 12/33 (36%), Positives = 20/33 (60%)
 Frame = -2

Query: 234 LLAFLLAELGTSGSIDGNNQLVIKGRFQQKQIE 266
           +L  L+  LGT GS+D   Q+V K   Q+ +++
Sbjct: 168 MLHLLMTGLGTEGSVDFKGQMVDKSYIQKPKMK 70
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|19705424|ref|NP_033465.1| proteasome 26S non-ATPase
subunit 3 [Mus musculus]
         (530 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

03414                                                                  31   1.0  
>03414
          Length = 1452

 Score = 31.2 bits (69), Expect = 1.0,   Method: Compositional matrix adjust.
 Identities = 17/62 (27%), Positives = 34/62 (54%)
 Frame = +2

Query: 394 LRHNVIKTGVRMISLSYSRISLADIAQKLQLDSPEDAEFIVAKAIRDGVIEASINHEKGY 453
           L+  V++  +R+++  Y+RI +  +++ L L   E  EF+    +  G +EA ++   G 
Sbjct: 125 LKIRVVEHNIRVMAKYYTRIRIKRMSELLDLTDGETEEFLSGLVVA-GTVEAKMDRLAGV 301

Query: 454 VQ 455
           VQ
Sbjct: 302 VQ 307
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|226423907|ref|NP_034053.2| 2',3'-cyclic nucleotide 3'
phosphodiesterase isoform 2 [Mus musculus]
         (420 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

06512                                                                  31   1.0  
03733                                                                  28   5.0  
>06512
          Length = 2288

 Score = 30.8 bits (68), Expect = 1.0,   Method: Compositional matrix adjust.
 Identities = 14/23 (60%), Positives = 17/23 (73%)
 Frame = +1

Query: 52  LFILRGLPGSGKSTLARLILEKY 74
           +  L G PGSGKST A L+L+KY
Sbjct: 331 IIFLTGGPGSGKSTQAELLLQKY 399
>03733
          Length = 1281

 Score = 28.5 bits (62), Expect = 5.0,   Method: Compositional matrix adjust.
 Identities = 22/56 (39%), Positives = 31/56 (55%), Gaps = 13/56 (23%)
 Frame = +1

Query: 25  GAKEKPEL----QFPFLQ---DEDTV------ATLHECKTLFILRGLPGSGKSTLA 67
           GAKE+P      +F FL+    E+ V      AT  EC+ L ++ GLPGSGK+  +
Sbjct: 802 GAKEEPYFPLKEEFAFLETLEQEERVRGCTPPATKEECEILMMV-GLPGSGKTVWS 966
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|28076897|ref|NP_080914.1|
CDP-diacylglycerol--inositol 3-phosphatidyltransferase
(phosphatidylinositol synthase) isoform 1 [Mus musculus]
         (213 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

07273                                                                  30   1.00 
06302                                                                  29   1.8  
10442                                                                  28   2.3  
16848                                                                  27   5.0  
>07273
          Length = 1359

 Score = 29.6 bits (65), Expect = 1.00,   Method: Compositional matrix adjust.
 Identities = 13/50 (26%), Positives = 27/50 (54%)
 Frame = +2

Query: 108  HLHSSVVRGSESHKMIDLSGNPVLRIYYTSRPALFTLCAGNELFYCLLYL 157
            HL++ + R  + HK + +  NP+ ++ Y  R  +F    G  +  C+L++
Sbjct: 1064 HLYNILCRNEDRHKTLKVVSNPLDKVIYNVRMHIFQAVVGFHI--CVLFV 1207
>06302
          Length = 773

 Score = 28.9 bits (63), Expect = 1.8,   Method: Compositional matrix adjust.
 Identities = 12/20 (60%), Positives = 14/20 (70%)
 Frame = -1

Query: 135 YTSRPALFTLCAGNELFYCL 154
           Y + P  +TLCA N LFYCL
Sbjct: 686 YYNIPTFWTLCASNVLFYCL 627
>10442
          Length = 338

 Score = 28.5 bits (62), Expect = 2.3,   Method: Compositional matrix adjust.
 Identities = 12/20 (60%), Positives = 14/20 (70%)
 Frame = -1

Query: 135 YTSRPALFTLCAGNELFYCL 154
           Y + P  +TLCA N LFYCL
Sbjct: 248 YYNIPTFWTLCASNVLFYCL 189
>16848
          Length = 266

 Score = 27.3 bits (59), Expect = 5.0,   Method: Compositional matrix adjust.
 Identities = 19/66 (28%), Positives = 30/66 (45%), Gaps = 8/66 (12%)
 Frame = -3

Query: 95  QLSMSLDVASHWLHLHSSVVRGSESHKMIDLSGNPVLRIYYTS--------RPALFTLCA 146
           Q+SMS     +  ++H  +   S S  M+ +  +P + IY T          P  +T CA
Sbjct: 261 QISMSATYVRYITYVHMYLTLISMSAYMLGI--DPTVHIYSTQISTSPLLVLPTFWTFCA 88

Query: 147 GNELFY 152
            N +FY
Sbjct: 87  SNAIFY 70
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|157841170|ref|NP_742114.3| Parkinson disease 7 domain
containing 1 [Mus musculus]
         (220 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

00372                                                                  29   1.1  
00728                                                                  28   3.3  
21253                                                                  28   4.2  
>00372
          Length = 1498

 Score = 29.3 bits (64), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 14/41 (34%), Positives = 21/41 (51%), Gaps = 4/41 (9%)
 Frame = +3

Query: 91   IPSCPGALTDLASSGSLARILQHFRSESKPICAI----GHG 127
            +PSCP  L  L +  S    L  F+ +++P+C      GHG
Sbjct: 1266 VPSCPPFLHILCAYNSFRDGLHEFQQDTRPVCGTDRKAGHG 1388
>00728
          Length = 540

 Score = 28.1 bits (61), Expect = 3.3,   Method: Compositional matrix adjust.
 Identities = 12/22 (54%), Positives = 14/22 (63%)
 Frame = -2

Query: 196 LVTGQNANSTVPAVQNLLFLCG 217
           L+TGQN   TV     +LFLCG
Sbjct: 395 LLTGQNLEGTVKYCYAMLFLCG 330
>21253
          Length = 1043

 Score = 27.7 bits (60), Expect = 4.2,   Method: Compositional matrix adjust.
 Identities = 15/34 (44%), Positives = 17/34 (50%), Gaps = 1/34 (2%)
 Frame = +1

Query: 109 RILQHFR-SESKPICAIGHGVAALCCATNEDRSW 141
           R+L HFR S SK  C   H    +CC T    SW
Sbjct: 838 RLLTHFRPSPSK--CNTVHSPCTICCTTKRKGSW 933
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|21312800|ref|NP_080638.1| hypothetical protein
LOC67759 [Mus musculus]
         (147 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

01700                                                                  28   1.1  
33956                                                                  27   2.3  
>01700
          Length = 1829

 Score = 28.5 bits (62), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 19/57 (33%), Positives = 26/57 (45%)
 Frame = -2

Query: 11   ENMKNQQEFMVTHARLQLERHLTMQNEMRERQMAMQIAWSREFLKYFGTFFGIATIS 67
            +N   QQ   VT   LQ    +T+Q   RE+  AMQ        K +GTF  + + S
Sbjct: 1279 QNXTLQQWNXVTSKMLQRRIFITLQXRAREKHRAMQXTVQAASTKIYGTFLTLISTS 1109
>33956
          Length = 276

 Score = 27.3 bits (59), Expect = 2.3,   Method: Compositional matrix adjust.
 Identities = 13/20 (65%), Positives = 16/20 (80%)
 Frame = -2

Query: 76  KKPAFLVPIVPLSFIFTYQY 95
           KK  FLV IV L+FIFT++Y
Sbjct: 173 KKLCFLVDIVYLAFIFTFRY 114
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|21313384|ref|NP_079965.1| coiled-coil domain
containing 51 [Mus musculus]
         (375 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

00558                                                                  30   1.1  
10536                                                                  27   9.6  
>00558
          Length = 2665

 Score = 30.4 bits (67), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 20/58 (34%), Positives = 29/58 (50%), Gaps = 3/58 (5%)
 Frame = +2

Query: 295  CSQMAGVLQLAQAPAHPGTVGPVDGALP-SSLLEHGSVIL--ALSEMEQRLEAQANRN 349
            CS +  V  L    AHP T+      LP S+LL+  S+++   + +  Q LE Q N N
Sbjct: 1265 CSLVWSVAWLVSTFAHPSTISRPCSLLPWSALLKRLSILIYXVIXKSPQ*LELQINNN 1438
>10536
          Length = 1110

 Score = 27.3 bits (59), Expect = 9.6,   Method: Compositional matrix adjust.
 Identities = 15/33 (45%), Positives = 21/33 (63%), Gaps = 1/33 (3%)
 Frame = -3

Query: 267 MKEQLRHSRQVYSCLEG-LREQLDGLEKTCSQM 298
           +KEQLRH+R+ +   +  L +  D LEK  SQM
Sbjct: 832 LKEQLRHAREKFDRTDRYLHDAEDELEKATSQM 734
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31088898|ref|NP_852071.1| arginyl-tRNA synthetase 2,
mitochondrial [Mus musculus]
         (578 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

10829                                                                  31   1.1  
02390                                                                  29   4.4  
>10829
          Length = 1878

 Score = 31.2 bits (69), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 22/71 (30%), Positives = 38/71 (53%), Gaps = 2/71 (2%)
 Frame = -3

Query: 266  YSGESFYREKSQDVLKLLDSKGLLQ--KTAEGNVVVDLSGTGGLSSVCTVMRSDGTSLYA 323
            Y G++FY  K   +   +DSK L +  +TA  N    LSG G  S + TV  +D ++   
Sbjct: 1384 YLGKAFYGRKRHPIQVRMDSKDLREEFETAISNSRCLLSGKGS-SGMATVGSTDMSAAEL 1208

Query: 324  TRDLAAAIHRM 334
             +++ A +H++
Sbjct: 1207 VQNITACMHQI 1175
>02390
          Length = 2275

 Score = 29.3 bits (64), Expect = 4.4,   Method: Compositional matrix adjust.
 Identities = 18/57 (31%), Positives = 27/57 (47%)
 Frame = -3

Query: 507 EVLYLSSQDLQPKHIVSYLLTLSHLAAVAHKTLKVKDSPPDVAGARLHLFKAVRSVL 563
           ++LY+ S   QPK  +SYL+   H  +  H  L + D      G R+H      S+L
Sbjct: 449 KILYIFSFGGQPKLSMSYLVFFHHW*SSNHVVLSLADHKGPSQGGRVHXHYCYPSLL 279
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31543971|ref|NP_062635.2| YKT6 v-SNARE protein [Mus
musculus]
         (198 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

10941                                                                  29   1.1  
>10941
          Length = 1286

 Score = 29.3 bits (64), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 13/54 (24%), Positives = 26/54 (48%)
 Frame = +1

Query: 104 QVDRIDWPVGSPATIQYTGLDDHLSKYQNPREADPMSKVQAELDETKIILHNTM 157
           Q +R+  P      + + GLDD L++   PR  D + ++   +     ++HN +
Sbjct: 511 QTERLILPREEGDGVHHGGLDDLLAREHPPRHRDRLRRITVGVVSLTSVVHNVI 672
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|39930435|ref|NP_081622.1| coiled-coil domain
containing 44 [Mus musculus]
         (294 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

13442                                                                  30   1.1  
32945                                                                  29   2.5  
27921                                                                  27   8.4  
>13442
          Length = 1053

 Score = 30.0 bits (66), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 18/66 (27%), Positives = 30/66 (45%)
 Frame = +3

Query: 229 FICDASSLHQVRKKLDSLGLCPVSCSMEFIPHSKVQLAEPELEQAAHLIQALNNYEDVIH 288
           F+C    L  + K L   G    +    F P++ VQL E + +     +Q L +   +  
Sbjct: 435 FVCSPIVLSGLSKTLAQNGYSIENSEHMFTPNNLVQLTEEDQKAYNVFVQKLRDVPGMED 614

Query: 289 VYDNIE 294
           +YDN+E
Sbjct: 615 IYDNVE 632
>32945
          Length = 403

 Score = 28.9 bits (63), Expect = 2.5,   Method: Compositional matrix adjust.
 Identities = 11/19 (57%), Positives = 14/19 (73%)
 Frame = +2

Query: 1   MMSWAAASLRMTAVPCFRV 19
           + SWA AS R TA+ CFR+
Sbjct: 86  ITSWATASSRFTAILCFRI 142
>27921
          Length = 418

 Score = 27.3 bits (59), Expect = 8.4,   Method: Compositional matrix adjust.
 Identities = 12/29 (41%), Positives = 17/29 (58%)
 Frame = +2

Query: 41  AAPHRTLHVSATASAGHNKWSKVRHIKGP 69
           +A  RT+++S     GH+ WS  R IK P
Sbjct: 299 SARFRTVNMSDKEKTGHSNWSASRFIKFP 385
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|13385890|ref|NP_080678.1| autophagy Apg3p/Aut1p-like
[Mus musculus]
         (314 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

00842                                                                  30   1.2  
>00842
          Length = 1507

 Score = 30.0 bits (66), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 12/24 (50%), Positives = 15/24 (62%)
 Frame = +1

Query: 74   LVTKNVPCYKRCKQMEYSDELEAI 97
            L TK  PC+K CK   YSD+  +I
Sbjct: 1012 LFTKLWPCWKGCKWFIYSDQCSSI 1083
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|41056093|ref|NP_075364.2| Ngg1 interacting factor
3-like 1 [Mus musculus]
         (376 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

15230                                                                  30   1.2  
>15230
          Length = 1240

 Score = 30.4 bits (67), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 14/42 (33%), Positives = 26/42 (61%)
 Frame = +3

Query: 321 HDVLDAASKGINVILCEHSNTERGFLSELQEMLGVHFENKIN 362
           ++ L+    GI++ LC HS   +  +SELQ ML + F+ +++
Sbjct: 624 YEHLNNYKTGIHICLCIHSYQAQLHISELQYMLTMPFQGRVS 749
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|41680647|ref|NP_598619.2| hypothetical protein
LOC75007 [Mus musculus]
         (459 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

16634                                                                  31   1.2  
03175                                                                  28   5.6  
>16634
          Length = 1139

 Score = 30.8 bits (68), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 18/45 (40%), Positives = 24/45 (53%)
 Frame = +1

Query: 104 PRIQQPELDFYCVKWIPWKGERTPIITQSTNGPCPLLAIMNILFL 148
           P  Q P L  +C+KW P  G +TP+I Q   GP P L   + L +
Sbjct: 265 PHAQLPVLKLHCIKWPP-SGPQTPVIKQCP-GPSPPLKFADQLTI 393
>03175
          Length = 1162

 Score = 28.5 bits (62), Expect = 5.6,   Method: Compositional matrix adjust.
 Identities = 13/27 (48%), Positives = 16/27 (59%)
 Frame = -1

Query: 105 RIQQPELDFYCVKWIPWKGERTPIITQ 131
           R+Q P    +C KW P+ G  TPII Q
Sbjct: 724 RVQLPVFKLHCTKW-PFSGL*TPIIKQ 647
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|58219050|ref|NP_081226.1| OCIA domain containing 2
[Mus musculus]
         (154 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

14433                                                                  28   1.2  
11688                                                                  26   5.4  
03525                                                                  26   6.5  
32828                                                                  26   7.4  
11122                                                                  25   9.2  
>14433
          Length = 520

 Score = 28.5 bits (62), Expect = 1.2,   Method: Compositional matrix adjust.
 Identities = 22/60 (36%), Positives = 30/60 (50%)
 Frame = -2

Query: 16  LPPLSKQSLLFCPKSKLHIHRGEIAKIIRECQEESFWKRALPFSLISMLVTQGLVHQGYL 75
           +PP  K+  L+   S+ H H G +     +C E S    A P+S+ S  V  GLV QG L
Sbjct: 384 IPPFFKRPCLWPAASRTHPHFGSLT----DCSEAS----AAPWSIDSRCV--GLVPQGXL 235
>11688
          Length = 590

 Score = 26.2 bits (56), Expect = 5.4,   Method: Compositional matrix adjust.
 Identities = 12/19 (63%), Positives = 14/19 (73%), Gaps = 1/19 (5%)
 Frame = +3

Query: 115 DQLRGA-GFGPEHNRHCLL 132
           D LRGA G  P+H +HCLL
Sbjct: 63  DPLRGAAGADPDHRQHCLL 119
>03525
          Length = 1234

 Score = 26.2 bits (56), Expect = 6.5,   Method: Compositional matrix adjust.
 Identities = 14/41 (34%), Positives = 20/41 (48%)
 Frame = +1

Query: 34   IHRGEIAKIIRECQEESFWKRALPFSLISMLVTQGLVHQGY 74
            I RGE  +++RE    S WK+ LP  L  + +       GY
Sbjct: 1051 IVRGEERRVVREIYSMSCWKQRLPRKLSKIEMVAIFCAAGY 1173
>32828
          Length = 643

 Score = 25.8 bits (55), Expect = 7.4,   Method: Compositional matrix adjust.
 Identities = 12/26 (46%), Positives = 14/26 (53%)
 Frame = +2

Query: 113 FEDQLRGAGFGPEHNRHCLLTCEDCK 138
           F D+LR A     HN  CL+T   CK
Sbjct: 257 FSDRLRTASNNYSHNVCCLVTWHFCK 334
>11122
          Length = 1458

 Score = 25.4 bits (54), Expect = 9.2,   Method: Compositional matrix adjust.
 Identities = 7/30 (23%), Positives = 19/30 (63%)
 Frame = +2

Query: 19  LSKQSLLFCPKSKLHIHRGEIAKIIRECQE 48
           ++  +++FCP  K  +H  ++ ++ + CQ+
Sbjct: 821 ITPNTVIFCPSQKPLLHNSQLQRLSQHCQD 910
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|20304089|ref|NP_034095.1| crystallin, beta A1 [Mus
musculus]
         (215 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

11538                                                                  29   1.3  
>11538
          Length = 1381

 Score = 29.3 bits (64), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 11/26 (42%), Positives = 16/26 (61%)
 Frame = +1

Query: 63   VRSLKVECGAWIGYEHTSFCGQQFIL 88
            V SLK+ C  ++ Y+H+ FC   F L
Sbjct: 1138 VSSLKMSCIVYVVYDHSQFCCCIFCL 1215
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|45439304|ref|NP_034544.1| huntingtin [Mus musculus]
         (3120 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

31514                                                                  33   1.3  
01880                                                                  33   1.9  
02365                                                                  31   6.4  
>31514
          Length = 381

 Score = 33.5 bits (75), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 21/72 (29%), Positives = 33/72 (45%)
 Frame = -1

Query: 683 VPDRDVRVSVKALALSCIGAAVALHPESFFSRLYKVPLNTTESTEEQYVSDILNYIDHGD 742
           +P+R VR  +     SCIG      P   +  L+ V     ++  +QYV  +++Y+  G 
Sbjct: 213 MPNRLVRAHIIVSLHSCIGKDFEASPSKLYCALHVVVEGGCDAWSQQYVVTMVSYLATG- 37

Query: 743 PQVRGATAILCG 754
             VRG    L G
Sbjct: 36  --VRGHNGKLLG 7
>01880
          Length = 2207

 Score = 33.1 bits (74), Expect = 1.9,   Method: Composition-based stats.
 Identities = 13/28 (46%), Positives = 19/28 (67%), Gaps = 2/28 (7%)
 Frame = +1

Query: 872  HRGAHHYTGFLK--LQERVLNNVVIYLL 897
            H+  HHYTGFLK  L  +  +N+ IY++
Sbjct: 2056 HKKKHHYTGFLKLFLNHQAFSNIYIYII 2139
>02365
          Length = 1804

 Score = 31.2 bits (69), Expect = 6.4,   Method: Composition-based stats.
 Identities = 16/46 (34%), Positives = 29/46 (63%), Gaps = 1/46 (2%)
 Frame = +3

Query: 2733 MDKTVAEPVSRLLESTLRSSHLPSQIGALH-GILYVLECDLLDDTA 2777
            +DK+  +PV R+LE  L S H+ + +   + G++++LE +  DD A
Sbjct: 225  LDKSTEDPVVRVLEEELISKHMKTIVEMENSGVVHMLENNKTDDLA 362
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|110625813|ref|NP_083379.2| arginine-rich, mutated in
early stage tumors [Mus musculus]
         (179 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

25286                                                                  28   1.4  
>25286
          Length = 766

 Score = 28.5 bits (62), Expect = 1.4,   Method: Compositional matrix adjust.
 Identities = 15/45 (33%), Positives = 28/45 (62%), Gaps = 3/45 (6%)
 Frame = -1

Query: 89  VSKPLAHHIPVEKICEKLK---KKDSQICELKYDKQIDLSTVDLK 130
           V++P  H +PV++ CE ++   KK  +  E K  KQI++S + ++
Sbjct: 172 VNQPSTHILPVKQ*CENMQTTNKKQGKHPETKKTKQINISHMTIR 38
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|7242183|ref|NP_035264.1| paraoxonase 1 [Mus musculus]
         (355 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

30003                                                                  30   1.4  
20038                                                                  30   1.5  
>30003
          Length = 491

 Score = 30.0 bits (66), Expect = 1.4,   Method: Compositional matrix adjust.
 Identities = 12/26 (46%), Positives = 14/26 (53%)
 Frame = +3

Query: 269 DNISVDPVTGDLWVGCHPNGMRIFFY 294
           DNI VD  TG L+V  HP   +   Y
Sbjct: 111 DNIQVDQTTGHLYVASHPVAYKFIMY 188
>20038
          Length = 986

 Score = 30.0 bits (66), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 22/65 (33%), Positives = 29/65 (44%)
 Frame = -1

Query: 225 GIGISLDGKYVYIAELLAHKIHVYEKHANWTLTPLKVLNFDTLVDNISVDPVTGDLWVGC 284
           G+G  LD   V   +   H +H +  H  + L PL ++NFD LVD             G 
Sbjct: 761 GVGYHLDDALVQHGQ---HSLHGHVHHVAF-LGPLVLVNFDKLVDGQE----------GA 624

Query: 285 HPNGM 289
           HP GM
Sbjct: 623 HPGGM 609
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|119964714|ref|NP_796110.2| furry homolog-like isoform
2 [Mus musculus]
         (869 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

09084                                                                  32   1.5  
>09084
          Length = 868

 Score = 31.6 bits (70), Expect = 1.5,   Method: Composition-based stats.
 Identities = 28/101 (27%), Positives = 45/101 (44%), Gaps = 22/101 (21%)
 Frame = -1

Query: 366 LYPLITCLLCVSQKQFFL---NNWHIFL-QNCLSHLKNKDPKMSRVALESLYRLLWVYVI 421
           L+P I+CL  +    FF+    N H+FL  +CL+ LK K   +    +  L++  W++  
Sbjct: 643 LFPFISCLNILDLYNFFIKCKKNSHLFLFISCLNILKCKIFLLFVQFI--LFKYSWLFFF 470

Query: 422 RIKCES------------------NTVTQSRLMSIVSALFP 444
            IKC+                   N    S L ++VS L+P
Sbjct: 469 SIKCKKLCRVCSLIKCLNEDYFLINCKKISALFAVVSCLYP 347
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|21703762|ref|NP_663355.1| eukaryotic translation
initiation factor 3, subunit M [Mus musculus]
         (374 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

06824                                                                  30   1.5  
31560                                                                  30   1.9  
07441                                                                  27   9.1  
>06824
          Length = 789

 Score = 30.0 bits (66), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 19/37 (51%), Positives = 24/37 (64%)
 Frame = +3

Query: 101 LRLQLLSNLFHGMDKNTPVRYTVYCSLIKVAASCGAI 137
           L L L+ +LF+G+ KNTP  Y  Y S IK  A CG+I
Sbjct: 93  LNLFLI*HLFNGLIKNTPNFY--YLSFIK-NAYCGSI 194
>31560
          Length = 597

 Score = 29.6 bits (65), Expect = 1.9,   Method: Compositional matrix adjust.
 Identities = 23/79 (29%), Positives = 39/79 (49%), Gaps = 2/79 (2%)
 Frame = +2

Query: 54  KEDDKDVESVMNSVVSLLLILEP--DKQEALIESLCEKLVKFREGERPSLRLQLLSNLFH 111
             D   +ES++N+ ++ LL+  P    Q+ L+  L            PS+R+ LL ++  
Sbjct: 296 SSDXGSMESLINNYIARLLVFHPL*HFQQLLLGLL-------HPAGSPSIRITLLFSVSD 454

Query: 112 GMDKNTPVRYTVYCSLIKV 130
           GM  +TP+      SLI+V
Sbjct: 455 GMRTDTPLS-----SLIRV 496
>07441
          Length = 375

 Score = 27.3 bits (59), Expect = 9.1,   Method: Composition-based stats.
 Identities = 14/39 (35%), Positives = 20/39 (51%)
 Frame = +3

Query: 141 PTELDQVRKWISDWKLTTEKKHTLLRLLYEALVDCKKSD 179
           PT L  +R   +D K T+EKK      +Y + +DC   D
Sbjct: 198 PTALGHIRTEHNDRKQTSEKKMEYNLTIYTSCIDCFMGD 314
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|226342964|ref|NP_937810.2| transmembrane protein 63b
[Mus musculus]
         (832 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

13447                                                                  32   1.5  
18525                                                                  29   9.6  
>13447
          Length = 759

 Score = 31.6 bits (70), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 26/87 (29%), Positives = 44/87 (50%)
 Frame = -3

Query: 189 SFGRTTIANLKSGNNLLWLHTSFAFLYLLLTVYSMRRHTSKMRYKEDDLVKRTLFINGIS 248
           SFGR ++ +  +  +L +L+  FAF  +L+TV++      K++YK  D+ K    +N + 
Sbjct: 727 SFGRQSLQD--TI*HLFYLY--FAFKNILVTVFTKNHECKKLKYK--DISKSNSMLNTMI 566

Query: 249 KYAESEKIKKHFEEAYPNCTVLEARPC 275
           KY   E +       Y +C   E  PC
Sbjct: 565 KYYHMEMV------IYMSC--FELSPC 509
>18525
          Length = 626

 Score = 28.9 bits (63), Expect = 9.6,   Method: Compositional matrix adjust.
 Identities = 17/47 (36%), Positives = 26/47 (55%)
 Frame = -2

Query: 336 YTKLEQRLKEDYRREKEKVNEKPLGMAFVTFHNETITAIILKDFNVC 382
           +TKL    KED R  KEK+   PL  +   F  E++T+ ++ D + C
Sbjct: 166 FTKLHLEDKEDDRSIKEKIQALPLTTSHTIF--ESLTSDMICDDDTC 32
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|27501448|ref|NP_034709.1| eukaryotic translation
initiation factor 6 [Mus musculus]
         (245 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

27291                                                                  29   1.5  
18377                                                                  28   4.5  
>27291
          Length = 435

 Score = 29.3 bits (64), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 18/59 (30%), Positives = 32/59 (54%)
 Frame = -2

Query: 94  IRRVEERLSALGNVTTCNDYVALVHPDLDRETEEILADVLKVEVFRQTVADQVLVGSYC 152
           I++V +RL ++       + V  + PDL   TE    +V+K E F+Q +   +L+G+Y 
Sbjct: 344 IKKVHQRLESMLFQMRFQEMVDDIKPDLVSATEAC-EEVMKSERFKQLLELVLLMGNYL 171
>18377
          Length = 748

 Score = 27.7 bits (60), Expect = 4.5,   Method: Compositional matrix adjust.
 Identities = 13/44 (29%), Positives = 25/44 (56%), Gaps = 1/44 (2%)
 Frame = -1

Query: 12  EVGCFAKLTNAYCLVAIGGSENFYSV-FEGELSDAIPVVHASIA 54
           ++GC       YCL+AI    NF  + +EG+ +D + ++H  ++
Sbjct: 400 KLGCTVSYCPRYCLIAISSPRNFC*LPYEGDKTDRL-LIHQRLS 272
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31542468|ref|NP_766099.2| abhydrolase domain
containing 10 [Mus musculus]
         (297 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

03656                                                                  30   1.5  
19704                                                                  29   2.2  
13372                                                                  28   4.9  
>03656
          Length = 729

 Score = 29.6 bits (65), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 18/62 (29%), Positives = 27/62 (43%)
 Frame = -1

Query: 77  SNMNGIKAVAVEEFCKSLGHAFIRFDYSGIGSSDGNLAECTVGKWRKDVLSILDDVAEGP 136
           S+ NG++   V   CK     F   DYSG  S     + C   K   D L I + + + P
Sbjct: 510 SHFNGLEKTRVNSLCKQQRTTFTNEDYSGKCSI*PLYSTC---KHHLDSLXITEKIRKTP 340

Query: 137 QI 138
           ++
Sbjct: 339 KL 334
>19704
          Length = 804

 Score = 29.3 bits (64), Expect = 2.2,   Method: Compositional matrix adjust.
 Identities = 19/71 (26%), Positives = 31/71 (43%), Gaps = 1/71 (1%)
 Frame = -2

Query: 170 ADGLVTQYHALPVETQKEIEM-KGEWTLPSRYNKEGYFRIPYSFIKEAEHHCLLHSPIPV 228
            D    ++   PVE    +E+  GE+ L   +N  G +        E   +C LHSP+P+
Sbjct: 695 TDDRTLRFLQTPVEAMLAVELASGEFXL--LFNVVGLYVKKQERGAECRRYCGLHSPLPL 522

Query: 229 TCPVRLLHGMK 239
             P   L+  +
Sbjct: 521 VIPALTLYATQ 489
>13372
          Length = 468

 Score = 28.1 bits (61), Expect = 4.9,   Method: Compositional matrix adjust.
 Identities = 14/38 (36%), Positives = 20/38 (52%)
 Frame = +1

Query: 220 CLLHSPIPVTCPVRLLHGMKDEIVPWQRSLQVADRIVS 257
           CL+H    V CP  +LH   D+IVP     ++   +VS
Sbjct: 214 CLIH----VRCPTLMLHAEDDKIVPIDLGKKLFQSVVS 315
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31981983|ref|NP_033313.2| stromal interaction
molecule 1 [Mus musculus]
         (685 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

13673                                                                  31   1.5  
02521                                                                  31   1.9  
30643                                                                  30   3.3  
08389                                                                  29   6.4  
>13673
          Length = 2904

 Score = 31.2 bits (69), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 16/46 (34%), Positives = 22/46 (47%)
 Frame = -1

Query: 507  QLGLGSQRDLTHSDSESSLHMSDRQRVAPKPPQMGRAADEALNAMP 552
            +LGLG  R  TH + +   H     RV   PP   RA D  +++ P
Sbjct: 1593 ELGLGGARVTTHQNVQIPPHFVLASRVLGLPPNKARAMDRLMSSCP 1456
>02521
          Length = 1487

 Score = 30.8 bits (68), Expect = 1.9,   Method: Compositional matrix adjust.
 Identities = 30/123 (24%), Positives = 58/123 (47%)
 Frame = -2

Query: 215  MLVVSIVIGVGGCWFAYIQNRYSKEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRT 274
             LVV +++ VG   F Y  N  SK   K++   LEG+   +   H + E+    ++   +
Sbjct: 1453 FLVVGLLVAVGILAFNYW-NLSSKN--KELSMTLEGM---QADFHSVSEKRLVMEKRAIS 1292

Query: 275  VEVEKVHLEKKLRDEINLAKQEAQRLKELREGTENERSRQKYAEEELEQVREALRKAEKE 334
            + V+   L+ KL    N A ++   + ELR    +  S+ +   + LEQ +  +++ + +
Sbjct: 1291 LNVDVADLQTKLNQIQNSASEKDNAVTELRGQVASLTSQLEKTSQSLEQAKTEVQQVQTD 1112

Query: 335  LES 337
              S
Sbjct: 1111 KTS 1103
>30643
          Length = 554

 Score = 30.0 bits (66), Expect = 3.3,   Method: Compositional matrix adjust.
 Identities = 26/79 (32%), Positives = 40/79 (50%), Gaps = 6/79 (7%)
 Frame = -2

Query: 226 GCWF----AYIQNRYSKEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVH 281
           GC      + I NR +    K++   L+GL+ A++  H+L ERL   Q +    EV    
Sbjct: 400 GCLRHSAPSRIVNRIAVCSKKRLDVALQGLNEAKKQNHNLMERLQTMQNDVSESEVRCAE 221

Query: 282 LEKKLRDEINL--AKQEAQ 298
           LE ++R   NL   +QEA+
Sbjct: 220 LEGQIRQLNNLLVQRQEAE 164
>08389
          Length = 962

 Score = 28.9 bits (63), Expect = 6.4,   Method: Compositional matrix adjust.
 Identities = 19/40 (47%), Positives = 23/40 (57%)
 Frame = +1

Query: 305 EGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAP 344
           EG E + S  K+   EL ++RE L  AEKELE   S  AP
Sbjct: 715 EGAEKDLSSTKH---ELLKIREMLELAEKELEKKVSMTAP 825
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|56797739|ref|NP_064350.2| malonyl-CoA decarboxylase
[Mus musculus]
         (492 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

15161                                                                  31   1.5  
27291                                                                  29   4.9  
>15161
          Length = 1228

 Score = 30.8 bits (68), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 15/37 (40%), Positives = 21/37 (56%), Gaps = 3/37 (8%)
 Frame = -1

Query: 42  LLRRAVPPTPAYELREKTP---APAEGQCADFVSFYG 75
           LLR ++PP PA    EKT     P   +  DF++F+G
Sbjct: 565 LLRSSLPPVPAXVFSEKTTFASLPCLIKVYDFITFFG 455
>27291
          Length = 435

 Score = 28.9 bits (63), Expect = 4.9,   Method: Composition-based stats.
 Identities = 15/40 (37%), Positives = 21/40 (52%)
 Frame = +3

Query: 76  GLAEASQRAELLGRLAQGFGVDHGQVAEQSAGVLQLRQQA 115
           G  + +Q   +LG    G  + HG     + GVLQLRQ+A
Sbjct: 9   GFVDEAQDVRVLGLYDLGQEMKHGDRTVLTLGVLQLRQEA 128
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|58037293|ref|NP_082549.1| phosphoglycerate mutase
family member 5 [Mus musculus]
         (287 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

03950                                                                  30   1.5  
33888                                                                  28   3.2  
00180                                                                  27   7.2  
>03950
          Length = 1369

 Score = 29.6 bits (65), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 14/36 (38%), Positives = 21/36 (58%)
 Frame = -1

Query: 155 TTDIISKHLPGVSRVSTDLLREGAPIEPDPPVSHWK 190
           TTD+  K L  +++VS D+L+E    E    V HW+
Sbjct: 979 TTDLKRKQLSFLTKVSFDVLKERGKDELRGMVRHWQ 872
>33888
          Length = 461

 Score = 28.5 bits (62), Expect = 3.2,   Method: Compositional matrix adjust.
 Identities = 16/29 (55%), Positives = 20/29 (68%)
 Frame = +2

Query: 166 VSRVSTDLLREGAPIEPDPPVSHWKPEAV 194
           VS + TD+L  G  IE DPP+  WKPE+V
Sbjct: 281 VSLMDTDIL*NGQ-IE-DPPIPPWKPESV 361
>00180
          Length = 1085

 Score = 27.3 bits (59), Expect = 7.2,   Method: Compositional matrix adjust.
 Identities = 10/16 (62%), Positives = 10/16 (62%)
 Frame = -3

Query: 184 PPVSHWKPEAVYYEDG 199
           PPV HWKP AV   D 
Sbjct: 588 PPVDHWKPRAVCLHDA 541
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|121949760|ref|NP_035735.2| thymopoietin isoform alpha
[Mus musculus]
         (693 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

07645                                                                  31   1.6  
31334                                                                  30   4.5  
>07645
          Length = 1433

 Score = 31.2 bits (69), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 13/32 (40%), Positives = 19/32 (59%)
 Frame = -2

Query: 642  MGSSTMGRRYLWLKDCKISPASKNKLTVAPFK 673
            + S+T+ R YLWL  C IS   + K+ V  F+
Sbjct: 1087 LSSTTLIRPYLWLXVCNISNLLRKKVVVTNFE 992
>31334
          Length = 323

 Score = 29.6 bits (65), Expect = 4.5,   Method: Compositional matrix adjust.
 Identities = 13/38 (34%), Positives = 17/38 (44%)
 Frame = +3

Query: 247 RDPPRETCTDTALPGKGQTHKLAPGRSLFIPSESSYDR 284
           + PP   C    LPGK QTH   P      P+  +Y +
Sbjct: 27  QSPPSSLCLHNCLPGKCQTH--PPSHCCVTPAACAYQK 134
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|154090957|ref|NP_997145.2| androgen binding protein
epsilon [Mus musculus]
         (114 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

33733                                                                  27   1.6  
>33733
          Length = 424

 Score = 27.3 bits (59), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 10/36 (27%), Positives = 18/36 (50%)
 Frame = -1

Query: 70  GLKAKTEDMKLMTTILFSSECRSYYTKEVLKNILVK 105
           G +   +D K + T+LF  ECR   +  ++  +L  
Sbjct: 358 GCRNTCDDCKCLLTVLFCVECRLTSSVSIITTVLCN 251
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|21312510|ref|NP_082341.1| canopy 3 homolog [Mus
musculus]
         (276 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

11667                                                                  30   1.6  
>11667
          Length = 1227

 Score = 29.6 bits (65), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 14/41 (34%), Positives = 23/41 (56%), Gaps = 3/41 (7%)
 Frame = +3

Query: 161 DLKKQCDVLVEEFEEVIEDWYR---NHQEEDLTEFLCANHV 198
           D  K+C  ++EE E V+ED++R   +  EE   ++ C   V
Sbjct: 72  DASKECHPMLEEHENVVEDFWREGIDRDEEKFHDYFCIQRV 194
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|21703884|ref|NP_663418.1| L-2-hydroxyglutarate
dehydrogenase [Mus musculus]
         (464 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

04330                                                                  30   1.6  
>04330
          Length = 1165

 Score = 30.4 bits (67), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 15/44 (34%), Positives = 23/44 (52%), Gaps = 6/44 (13%)
 Frame = -3

Query: 122 YEYCNLKGIPYRQCGKLIVAVEQEEIP------RLQALYERGLQ 159
           +  C+L+  PY  CG L +A+E   +P       LQ +Y+  LQ
Sbjct: 362 FSVCSLRTFPYMACGLLRLAMEW*RVP*XVYCKNLQVVYDTNLQ 231
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31559964|ref|NP_653133.2| coiled-coil domain
containing 52 [Mus musculus]
         (860 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

12630                                                                  31   1.6  
>12630
          Length = 1714

 Score = 31.2 bits (69), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 16/33 (48%), Positives = 22/33 (66%), Gaps = 2/33 (6%)
 Frame = -3

Query: 417 TAEILSLREENSTMQARLQQYMVT--TDEQLIS 447
           TA++LS+R   S +Q +L QYM+T  T E  IS
Sbjct: 767 TADLLSIRSSQSYIQCKLXQYMLTKCTIEGYIS 669
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|62543571|ref|NP_766391.2| dedicator of cytokinesis 4
[Mus musculus]
         (1978 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

36178                                                                  33   1.6  
22704                                                                  32   2.5  
02404                                                                  31   4.5  
38675                                                                  31   6.2  
>36178
          Length = 460

 Score = 32.7 bits (73), Expect = 1.6,   Method: Composition-based stats.
 Identities = 24/101 (23%), Positives = 46/101 (45%), Gaps = 3/101 (2%)
 Frame = +3

Query: 1725 LSPRDRPCSAIYPTPVEPSQRML--FNHIGDGALPRSDPNL-SAPEKAVNPTPSSWSLDS 1781
            +SPR  PC+   P P +  +++   + +  +  +P   PN+  A    V+PT S +S  +
Sbjct: 93   ISPRATPCTDDTPLPPDTEEKVWGRYGYEDNIRMPELGPNIHKAHISTVSPTASGYSGPT 272

Query: 1782 GKEAKNMSDSGKLISPPVPPRPTQTASPARHTTSVSPSPAG 1822
                ++++ S +        R T  A P     +++PS  G
Sbjct: 273  STGGRSLAASQR-------HRHTAMAVPKFRHAAITPSTIG 374
>22704
          Length = 445

 Score = 32.0 bits (71), Expect = 2.5,   Method: Composition-based stats.
 Identities = 13/43 (30%), Positives = 21/43 (48%)
 Frame = -2

Query: 1254 MQTEWQRKEHLHLTIIQNFDRGKCWENGIILCRKIAEQYESYY 1296
            M+ EW +  H H + +   D  K   N + LC    +QYE ++
Sbjct: 273  MEVEWNQS*HFHPSQLNTLDHAKHCNNVLYLCYANVQQYEQHH 145
>02404
          Length = 1529

 Score = 31.2 bits (69), Expect = 4.5,   Method: Compositional matrix adjust.
 Identities = 18/42 (42%), Positives = 26/42 (61%), Gaps = 1/42 (2%)
 Frame = +1

Query: 734 CIQELLMSVRFFLSQESK-GTGALSQSQAVFLSSFPAVYSEL 774
           CI+ELL SV  +   E+K     LS+SQ+ FL ++ + YS L
Sbjct: 31  CIRELLSSVT*YYQNENKQNLNILSKSQSYFLMNYXSFYSTL 156
>38675
          Length = 821

 Score = 30.8 bits (68), Expect = 6.2,   Method: Composition-based stats.
 Identities = 19/69 (27%), Positives = 33/69 (47%), Gaps = 3/69 (4%)
 Frame = +2

Query: 1757 PRSDPN---LSAPEKAVNPTPSSWSLDSGKEAKNMSDSGKLISPPVPPRPTQTASPARHT 1813
            P ++P+   LS+     +P+  SW L +     ++  S +   PP+  R  +TA+  R  
Sbjct: 299  PNTEPDPSPLSSNRSGGSPSGHSWELVNSALPSSIESSRQ--QPPLQQRCAKTATSPRPE 472

Query: 1814 TSVSPSPAG 1822
             S+SP   G
Sbjct: 473  PSISPGKLG 499
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6755688|ref|NP_035633.1| syntaxin binding protein 2
[Mus musculus]
         (593 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

12886                                                                  31   1.6  
>12886
          Length = 2104

 Score = 30.8 bits (68), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 13/46 (28%), Positives = 28/46 (60%)
 Frame = +1

Query: 535 IVYIVGGVAMSEMRAAYEVTRATEGKWEVLIGSSHILTPTRFLDDL 580
           +VY +GGV  +E+ A   + +  +G  + ++ +S++++  R LD L
Sbjct: 658 LVYFLGGVTFAEIAALRFLAQQDDGGTDYVVATSNLMSGHRLLDCL 795
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|7657031|ref|NP_056622.1| 5',3'-nucleotidase,
cytosolic [Mus musculus]
         (200 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

18697                                                                  29   1.6  
05011                                                                  28   3.3  
30271                                                                  27   6.6  
>18697
          Length = 1565

 Score = 28.9 bits (63), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 16/59 (27%), Positives = 25/59 (42%)
 Frame = -2

Query: 112 GEKYRWVEQNLGPEFVERIILTRDKTVVMGDLLIDDKDNIQGLEETPSWEHILFTCCHN 170
           G K R+      P     + LT      +GD L+  ++N QG++ T  W  +   C  N
Sbjct: 379 GSK*RFFSHKAAPRLASFLQLTLP*L*WLGDYLLYSQENSQGIQSTLLWVCLCGQCGMN 203
>05011
          Length = 420

 Score = 27.7 bits (60), Expect = 3.3,   Method: Compositional matrix adjust.
 Identities = 9/24 (37%), Positives = 15/24 (62%)
 Frame = -3

Query: 14  DGVLADFESGLLQGFRRRFPEEPH 37
           + +++D+ESGL+   R  FP   H
Sbjct: 415 EQIMSDYESGLMPAIRHSFPNTQH 344
>30271
          Length = 1321

 Score = 26.6 bits (57), Expect = 6.6,   Method: Compositional matrix adjust.
 Identities = 10/19 (52%), Positives = 15/19 (78%)
 Frame = -1

Query: 17  LADFESGLLQGFRRRFPEE 35
           ++DFE  +L+G  RRFPE+
Sbjct: 820 ISDFEGCVLRGMVRRFPEQ 764
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|89337262|ref|NP_796015.2| FAD-synthetase [Mus
musculus]
         (492 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

31203                                                                  30   1.6  
37124                                                                  29   4.0  
04185                                                                  28   7.8  
>31203
          Length = 1813

 Score = 30.4 bits (67), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 36/134 (26%), Positives = 52/134 (38%), Gaps = 17/134 (12%)
 Frame = -3

Query: 194  SEGSIAPILSEAQAHFGRRLSLGSYPDWSSN-----------YFQVKLILDSEEKEPLEE 242
            S G   P+    +   G+   LG   + SSN           Y Q  + L +  K+P E 
Sbjct: 1148 SNGQCKPLEKAGRPCTGKGQCLGK-AECSSNIKGVCTCIIGFYDQDGICLKA--KKPQER 978

Query: 243  C------LAYLTARLPQGSLVPYQPDAVEKAGEAVYKLAESGSCLGKKVAGALQTIETAL 296
            C      L+ L   LPQG +   +P  VEK GE V  +       G   +G  + +E A 
Sbjct: 977  CDAPGNALSTLLVLLPQG-ICECRPSFVEKKGECVPAIP-----AGDPCSGLRECVENAE 816

Query: 297  AQYHLSQLCVGFNG 310
                +  LC   +G
Sbjct: 815  CTTAMGGLCECNDG 774
>37124
          Length = 540

 Score = 29.3 bits (64), Expect = 4.0,   Method: Compositional matrix adjust.
 Identities = 16/48 (33%), Positives = 27/48 (56%), Gaps = 5/48 (10%)
 Frame = +2

Query: 31  HTQDTNTYF-----LCRTLRSLGVQVCRVSVVPDEVATIASEVNSFSR 73
           H+ D  T+F     LCRTLRSL  +V R++++ D    + + +   +R
Sbjct: 92  HSND*KTFFCYHLTLCRTLRSLWRRVGRLALLSDVSTFVTAALIGMTR 235
>04185
          Length = 1106

 Score = 28.1 bits (61), Expect = 7.8,   Method: Compositional matrix adjust.
 Identities = 16/52 (30%), Positives = 27/52 (51%), Gaps = 1/52 (1%)
 Frame = -1

Query: 80  TAGGIGPTHDDVTFEAVAQAFGE-ELKPHPELQAAIKTLGGEGWEKLSMVPS 130
           TA  + P+H     + + Q+ G   ++P P+L +   TL G  W+K  + PS
Sbjct: 668 TAWPLSPSHQ--PRDVLPQSAGSGNVRPAPDLXSPASTLHGPEWQKCPVCPS 519
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|110625732|ref|NP_997102.2| hypothetical protein
LOC106821 [Mus musculus]
         (152 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

09786                                                                  28   1.7  
11331                                                                  26   6.0  
>09786
          Length = 445

 Score = 28.1 bits (61), Expect = 1.7,   Method: Compositional matrix adjust.
 Identities = 11/35 (31%), Positives = 19/35 (54%)
 Frame = +3

Query: 88  SHKPTYENLQKSLEAMKSHCLKNGVTDLSMPRIGC 122
           S  P YENL+ +L++  +H +    TD+  P +  
Sbjct: 12  SLSPFYENLELALQSAPNHIIPQTGTDIXPPTVAV 116
>11331
          Length = 520

 Score = 26.2 bits (56), Expect = 6.0,   Method: Compositional matrix adjust.
 Identities = 10/25 (40%), Positives = 14/25 (56%)
 Frame = -2

Query: 8  DPEGSRITYVKGDLFACPKTDSLAH 32
          DP G  + YVK +L+  P+ D   H
Sbjct: 90 DPHGGVLIYVKNNLYCKPRPDLEVH 16
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|12963663|ref|NP_075886.1| magnesium-dependent
phosphatase-1 [Mus musculus]
         (164 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

03846                                                                  28   1.7  
>03846
          Length = 911

 Score = 28.1 bits (61), Expect = 1.7,   Method: Compositional matrix adjust.
 Identities = 16/36 (44%), Positives = 20/36 (55%)
 Frame = -1

Query: 116 SQMVFFDDENRNIIDVGRLGVTCIHIRDGMSLQTLT 151
           S+M F  + NRN +  GR   TC H +  MSL T T
Sbjct: 905 SKMYFPSERNRNEL-FGRQHETCTHSQLSMSLMTKT 801
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|158517890|ref|NP_071299.3| interphotoreceptor matrix
proteoglycan 1 [Mus musculus]
         (798 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

26243                                                                  31   1.7  
>26243
          Length = 426

 Score = 31.2 bits (69), Expect = 1.7,   Method: Composition-based stats.
 Identities = 12/24 (50%), Positives = 12/24 (50%)
 Frame = +2

Query: 732 NLCPPGKTCVAGREQATPCRPPDH 755
           N CP G  C  G  QA PCR   H
Sbjct: 320 NFCPVGHFCPVGVSQALPCRNNSH 391
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|170650593|ref|NP_082086.2| Bardet-Biedl syndrome 7
[Mus musculus]
         (715 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

14741                                                                  31   1.7  
>14741
          Length = 585

 Score = 31.2 bits (69), Expect = 1.7,   Method: Compositional matrix adjust.
 Identities = 18/61 (29%), Positives = 27/61 (44%), Gaps = 3/61 (4%)
 Frame = +2

Query: 502 HDRPMNTLTLTGQFSFAEVHSWVVFCLPEV---PEKPPAGECATFYFQNTFLDTQLECVY 558
           H+RP N LT    F F       VFC P +   P++P     ++F+ +  F+       Y
Sbjct: 62  HERPPNCLTQVTVFLFGHESPSSVFCCPRIPLGPKRPLDSGLSSFFSKPNFMSADGNHTY 241

Query: 559 R 559
           R
Sbjct: 242 R 244
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|20149726|ref|NP_619592.1| phosphatidate
cytidylyltransferase 2 [Mus musculus]
         (444 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

01651                                                                  30   1.7  
27614                                                                  29   2.9  
10708                                                                  28   6.2  
07624                                                                  28   7.6  
>01651
          Length = 747

 Score = 30.4 bits (67), Expect = 1.7,   Method: Compositional matrix adjust.
 Identities = 18/57 (31%), Positives = 29/57 (50%), Gaps = 1/57 (1%)
 Frame = +1

Query: 332 YPFQIHSIALSTFASLIGPFG-GFFASGFKRAFKIKDFANTIPGHGGIMDRFDCQYL 387
           Y +Q  ++ L T+ SL+G        S  K   KI +  NT+   GGI  +F+ ++L
Sbjct: 91  YSYQTTTVHLVTWPSLLGVAQFNTTTSAIKIQXKIDNKDNTLKTVGGIASQFEIKHL 261
>27614
          Length = 424

 Score = 29.3 bits (64), Expect = 2.9,   Method: Composition-based stats.
 Identities = 17/50 (34%), Positives = 26/50 (52%)
 Frame = +3

Query: 4   LRQRVVREDAPPEDKESESEAKLDGETASDSESRAETAPLPTSVDDTPEV 53
           L +R + ED P  D E+++EAK++      S +R  T      VD+T  V
Sbjct: 165 LARRALHEDLPMTDTEADAEAKVEDNADDTSTARTTTPTTAMEVDETETV 314
>10708
          Length = 2775

 Score = 28.5 bits (62), Expect = 6.2,   Method: Compositional matrix adjust.
 Identities = 20/74 (27%), Positives = 36/74 (48%), Gaps = 15/74 (20%)
 Frame = -1

Query: 213  VIHNLFEGMIWFIVPISCVICNDIMAY--------MFGFFFGRTPLIKLSPKKTW----- 259
            V++ LF+    F+  I+C+I + ++AY         F  FF +  L  + P + W     
Sbjct: 1479 VLYQLFD----FVFYINCLIVSAMLAYNFHPC*PLQFSSFFTKGALAIIHPFQMWSLCVF 1312

Query: 260  --EGFIGGFFATVV 271
               GF+GGF++  +
Sbjct: 1311 WRSGFVGGFYSKFI 1270
>07624
          Length = 909

 Score = 28.1 bits (61), Expect = 7.6,   Method: Compositional matrix adjust.
 Identities = 12/30 (40%), Positives = 18/30 (60%)
 Frame = +3

Query: 5   RQRVVREDAPPEDKESESEAKLDGETASDS 34
           ++   +++A  EDKES+ E  LD E   DS
Sbjct: 270 KKDAEKDEAEKEDKESDKEKLLDDEKEMDS 359
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|39930425|ref|NP_081092.1| general transcription
factor IIF, polypeptide 2 [Mus musculus]
         (249 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

27352                                                                  29   1.7  
26652                                                                  27   5.8  
>27352
          Length = 377

 Score = 29.3 bits (64), Expect = 1.7,   Method: Compositional matrix adjust.
 Identities = 13/36 (36%), Positives = 21/36 (58%)
 Frame = -1

Query: 162 NIEYERKKKEDGKRARADKQHVLDMLFSAFEKHQYY 197
           N+ Y+R K E   RA AD+ ++LD+     + HQ +
Sbjct: 353 NVRYDRLKLESQTRAEADRNNILDLQAELRDLHQRF 246
>26652
          Length = 397

 Score = 27.3 bits (59), Expect = 5.8,   Method: Compositional matrix adjust.
 Identities = 12/37 (32%), Positives = 21/37 (56%)
 Frame = -2

Query: 205 ITKQPVGYLKEILKEIGIQNVKGIHKNTWELKPEYRH 241
           +T +P  +++E+L         GIH+NTW+ +  Y H
Sbjct: 234 VTTKPCLWIQELL---------GIHRNTWDQRTIYGH 151
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|40789298|ref|NP_796347.2| PTPRF interacting protein
alpha 2 [Mus musculus]
         (1256 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

06952                                                                  32   1.7  
31117                                                                  31   2.9  
27079                                                                  30   5.4  
>06952
          Length = 2102

 Score = 32.0 bits (71), Expect = 1.7,   Method: Compositional matrix adjust.
 Identities = 17/58 (29%), Positives = 32/58 (55%)
 Frame = -3

Query: 517 RLAEEIEKLRSELDQMKMRTGSLIEPTISRTHIDTSTELRYSVGSLVDSQSDYRTTKV 574
           R+AE+ E+ + +L  + MR  S I+P     H D  T   + +G++VD   ++ T ++
Sbjct: 264 RMAEQTEEQKKDLMVLGMR--STIDPVRHYKHTDLKTPKFFQMGTVVDDAYNFYTDRI 97
>31117
          Length = 856

 Score = 31.2 bits (69), Expect = 2.9,   Method: Compositional matrix adjust.
 Identities = 11/25 (44%), Positives = 15/25 (60%)
 Frame = +3

Query: 1026 EWLPSLGLPQYRSYFMECLVDARML 1050
            EW+  LG P Y+S F   ++D R L
Sbjct: 111  EWIEELGFPHYKSCFTTNMIDGRRL 185
>27079
          Length = 471

 Score = 30.0 bits (66), Expect = 5.4,   Method: Composition-based stats.
 Identities = 14/38 (36%), Positives = 21/38 (55%)
 Frame = -3

Query: 751 HRRKIAVVEEDGREDKATIKCETSPPPTPRAVRMTHTL 788
           H +   VVE  G+E+K+T     S PP P+  ++T  L
Sbjct: 367 HAKHAPVVEGHGKENKSTXCSPMSIPPAPKQTKLTWDL 254
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|47271535|ref|NP_666144.3| signal recognition particle
68 [Mus musculus]
         (625 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

19639                                                                  31   1.7  
21682                                                                  30   3.4  
>19639
          Length = 1132

 Score = 30.8 bits (68), Expect = 1.7,   Method: Compositional matrix adjust.
 Identities = 14/50 (28%), Positives = 25/50 (50%)
 Frame = -1

Query: 183 LEAQAYTAYLSGMLRFEHQEWKSAIEAFNKCKTIYEKLASAFTEEQAVLY 232
           L  Q Y      +L ++HQ+WK  I ++N  K +   L + + + Q  +Y
Sbjct: 151 LPCQPYYI*FHNILFYQHQDWKGIILSYNLIKLVDIILGARYDQLQFQVY 2
>21682
          Length = 435

 Score = 29.6 bits (65), Expect = 3.4,   Method: Composition-based stats.
 Identities = 17/57 (29%), Positives = 29/57 (50%), Gaps = 1/57 (1%)
 Frame = -3

Query: 534 ANDSHQTDTSSQVKDNTPLVERFESFCLDPSLVTKQANL-VHFPPGFQPIPCKPLFF 589
           +ND + T TSS +  +  ++ER     + P LV    +L +   P F P+P  P+ +
Sbjct: 208 SNDGNGTITSSMLSSSWNVLERKRQDMVRPFLVNMIRSLPIRIEPDFSPLPYMPILW 38
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|90186270|ref|NP_001035023.1| microtubule-associated
protein 2 isoform 1 [Mus musculus]
         (498 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

10194                                                                  30   1.7  
>10194
          Length = 1278

 Score = 30.4 bits (67), Expect = 1.7,   Method: Compositional matrix adjust.
 Identities = 29/108 (26%), Positives = 49/108 (45%), Gaps = 17/108 (15%)
 Frame = -3

Query: 353 NIKHSAGGGNVQIVTKKIDLSHVTSKCGSLKNIRHR--PGGG---RVKIESVKLDFKEKA 407
           N K +   GNV + T K  L+ +  + G ++N+R R  P G    + ++  +  DF EK 
Sbjct: 721 NEKRTVFVGNVPLKTDKKKLARLFKQFGKIENVRFRCAPVGDPTTKKRVAVITKDFHEKR 542

Query: 408 ------------QAKVGSLDNAHHVPGGGNVKIDSQKLNFREHAKARV 443
                       +A   +L    HV  G ++++DS KL+ +   K  V
Sbjct: 541 HNISAYICFKEDEAAKQALTLNGHVIDGLHLRVDSAKLSLKNLDKRSV 398
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|124244104|ref|NP_033151.2| ataxin 2 [Mus musculus]
         (1286 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

05174                                                                  32   1.8  
>05174
          Length = 1407

 Score = 32.0 bits (71), Expect = 1.8,   Method: Composition-based stats.
 Identities = 23/87 (26%), Positives = 37/87 (42%)
 Frame = -2

Query: 235  NVRMVHILTSVVGSKCEVQVKNGGIYEGVFKTYSPKCDLVLDAAHEKSTESSSGPKREEI 294
            N  M   L S V     +   +G I  G  K +    +L+LD +HE+   +S G   E++
Sbjct: 1361 NEDMASALESYVNKTVSIVTADGRIIVGTLKGFDQTINLILDESHERVFSTSQG--MEQV 1188

Query: 295  MESVLFKCSDFVVVQFKDTDSSYARRD 321
            +  +     D V V  +  D +  R D
Sbjct: 1187 ILGLYIVRGDNVAVIGEVDDETDGRVD 1107
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|13569852|ref|NP_076368.1| retinitis pigmentosa GTPase
regulator interacting protein 1 [Mus musculus]
         (1331 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

11195                                                                  32   1.8  
16039                                                                  32   2.4  
36929                                                                  30   8.1  
>11195
          Length = 1050

 Score = 32.0 bits (71), Expect = 1.8,   Method: Composition-based stats.
 Identities = 17/45 (37%), Positives = 23/45 (51%), Gaps = 7/45 (15%)
 Frame = +3

Query: 682 WISLDKVLGTVERVHGLATLAGA-------GGEDLGVLEYWMRLC 719
           W SLD V   VER+ G   +  A       GG D+G+   W++LC
Sbjct: 639 WSSLDTVWVRVERLWGSVRVDSA*QLYADDGGYDMGLSASWLKLC 773
>16039
          Length = 1815

 Score = 31.6 bits (70), Expect = 2.4,   Method: Composition-based stats.
 Identities = 13/28 (46%), Positives = 17/28 (60%)
 Frame = +1

Query: 792 FFTFPDHDTIIIPASSNPYFKDQALFPV 819
           F+TFPDH   IIP  S  Y +D +  P+
Sbjct: 709 FYTFPDHMNRIIPHVSYTYAQDLSXIPI 792
>36929
          Length = 494

 Score = 29.6 bits (65), Expect = 8.1,   Method: Composition-based stats.
 Identities = 15/34 (44%), Positives = 22/34 (64%)
 Frame = -2

Query: 209 VEKPEQRSSEECTQKAAELRASIKENVELIRLKK 242
           +E    R+ E+CTQKA   RA + + ++LI LKK
Sbjct: 493 IEHTAFRTREQCTQKATHTRAHMFKTLKLIILKK 392
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|214010170|ref|NP_038520.2| clusterin [Mus musculus]
         (448 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

28763                                                                  30   1.8  
>28763
          Length = 580

 Score = 30.0 bits (66), Expect = 1.8,   Method: Compositional matrix adjust.
 Identities = 19/58 (32%), Positives = 31/58 (53%)
 Frame = +3

Query: 321 NLRQELNDSLQVAERLTEQYKELLQSFQSKMLNTSSLLEQLNDQFNWVSQLANLTQGE 378
           +L +EL D+  VAER    Y++ L S +S++   S    QL D+ +       L+QG+
Sbjct: 21  DLERELRDTRTVAER----YEQELHSLRSRVAGISEDRHQLEDRLSAADAAHRLSQGQ 182
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|26024311|ref|NP_742160.1| B9 protein domain 2 [Mus
musculus]
         (175 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

16409                                                                  28   1.8  
28154                                                                  27   3.4  
13224                                                                  26   7.9  
05801                                                                  26   9.9  
>16409
          Length = 594

 Score = 28.1 bits (61), Expect = 1.8,   Method: Compositional matrix adjust.
 Identities = 13/38 (34%), Positives = 16/38 (42%)
 Frame = +3

Query: 82  SQDSFGRCQLAGYGFCHVPSSPGTHQLDCPTWRPLGSW 119
            Q+SF  C    +GF  V S    HQ D   W   G +
Sbjct: 84  EQNSFKICVCVCFGFVFVFSEY*LHQFDLSAWGKFGEF 197
>28154
          Length = 374

 Score = 27.3 bits (59), Expect = 3.4,   Method: Compositional matrix adjust.
 Identities = 16/45 (35%), Positives = 19/45 (42%), Gaps = 2/45 (4%)
 Frame = -1

Query: 55  AYWSHPIDLHFATKGLQGWPRLHLQVWSQDSFGR--CQLAGYGFC 97
           A W     L ++   L   PRLH    S DS+G   C    Y FC
Sbjct: 173 AAWKQSTALLYSPLRLNNTPRLHCTSASTDSWGAAICTADRYRFC 39
>13224
          Length = 1078

 Score = 26.2 bits (56), Expect = 7.9,   Method: Compositional matrix adjust.
 Identities = 14/32 (43%), Positives = 15/32 (46%)
 Frame = +2

Query: 18  ESSLFCKWGIHTGAAWKLLSGVREGQTQVDTP 49
           ES  F KWG+   A W L  G   G T   TP
Sbjct: 422 ESLGFFKWGLRLLACWGLAPGPHWGSTSAPTP 517
>05801
          Length = 1005

 Score = 25.8 bits (55), Expect = 9.9,   Method: Compositional matrix adjust.
 Identities = 12/47 (25%), Positives = 19/47 (40%)
 Frame = -3

Query: 24  KWGIHTGAAWKLLSGVREGQTQVDTPQIGDMAYWSHPIDLHFATKGL 70
           +WG     +W L    R    +  TP +G  + W H +    A + L
Sbjct: 196 RWGRSLLMSWALTKTNRRFVCEWSTPSLGSSSRWQHTV*RSLADRTL 56
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|28827824|ref|NP_780310.1| transmembrane protein 111
[Mus musculus]
         (261 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

06680                                                                  29   1.8  
>06680
          Length = 1247

 Score = 29.3 bits (64), Expect = 1.8,   Method: Compositional matrix adjust.
 Identities = 14/46 (30%), Positives = 23/46 (50%)
 Frame = +1

Query: 204  TGAAMAMPADTNKAFKTEWEALELTDHQWALDDVEEELMARDLHFE 249
             G    + AD  +  +TE     L++HQW  +D+E   +  D H+E
Sbjct: 1039 NGGTSLIFADLKERQRTE*NGTRLSNHQWCPNDLEAMRLDDDNHYE 1176
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31981340|ref|NP_036030.2| mannose-P-dolichol
utilization defect 1 [Mus musculus]
         (247 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

14046                                                                  29   1.8  
>14046
          Length = 895

 Score = 28.9 bits (63), Expect = 1.8,   Method: Compositional matrix adjust.
 Identities = 11/24 (45%), Positives = 16/24 (66%), Gaps = 1/24 (4%)
 Frame = -2

Query: 101 SSWGEALFLTLQTVAICFLV-MHY 123
            +WG+ +F+  Q V +CFL  MHY
Sbjct: 648 QNWGDFIFICFQCVIVCFLYKMHY 577
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6753618|ref|NP_034157.1| D-dopachrome tautomerase
[Mus musculus]
         (118 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

29920                                                                  27   1.8  
20797                                                                  25   8.7  
>29920
          Length = 547

 Score = 26.9 bits (58), Expect = 1.8,   Method: Compositional matrix adjust.
 Identities = 16/47 (34%), Positives = 26/47 (55%), Gaps = 1/47 (2%)
 Frame = -1

Query: 39  SVTIRPGMTLLMNKSTEPCAHLLVSSIGV-VGTAEQNRTHSASFFKF 84
           S+ I+    +LMN  +    H+++ +I    GT EQNRTH +S   +
Sbjct: 523 SMNIQSNHIVLMNIQSN---HIILMTIKYKSGTLEQNRTHLSSIIAY 392
>20797
          Length = 398

 Score = 24.6 bits (52), Expect = 8.7,   Method: Compositional matrix adjust.
 Identities = 10/24 (41%), Positives = 16/24 (66%)
 Frame = -3

Query: 44  PGMTLLMNKSTEPCAHLLVSSIGV 67
           PG+   M++S  P  H+L+SS+ V
Sbjct: 282 PGLDQSMSRSMPPSTHVLLSSVSV 211
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|19526878|ref|NP_598466.1| pyrroline-5-carboxylate
reductase family, member 2 [Mus musculus]
         (320 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

09672                                                                  30   1.9  
10629                                                                  27   8.8  
>09672
          Length = 1963

 Score = 29.6 bits (65), Expect = 1.9,   Method: Compositional matrix adjust.
 Identities = 21/66 (31%), Positives = 33/66 (50%), Gaps = 3/66 (4%)
 Frame = -2

Query: 70   VKPHIIPFILDEI-GADVQERHIVVSCAAGVTISSVEKKL--MAFQPAPKVIRCMTNTPV 126
            V PH++PF+ + I  AD + R   V     +      +KL  +  Q  P +I  +T+  V
Sbjct: 1923 VVPHVLPFVKENIRHADWRYRDAAVMAFGSILEGPDSEKLKPIVEQAMPMLIELLTDPSV 1744

Query: 127  VVREGA 132
            VVR+ A
Sbjct: 1743 VVRDTA 1726
>10629
          Length = 877

 Score = 27.3 bits (59), Expect = 8.8,   Method: Compositional matrix adjust.
 Identities = 27/94 (28%), Positives = 41/94 (43%), Gaps = 1/94 (1%)
 Frame = -2

Query: 139 THALVEDGKLLEQLMSSVGFCTEVEEDLIDAITGLSGSGPAYAFMALDALADGGVKMGVP 198
            H  +E+G LLE L   V  C      L   +  L G+GP      L A + G  ++ + 
Sbjct: 735 NHVSMEEGALLEPLSVGVHACNRAGVSLGSKVLIL-GAGPIGLVTLLVAQSMGATEIXIT 559

Query: 199 RRLAVRLGAQALLGAAK-MLLDSEDHPGQLKDNV 231
             +  RL     LGA   +LL+ +D   Q+ + V
Sbjct: 558 DLVQHRLDVAKELGATHTLLLNRDDTAEQISERV 457
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|20127150|ref|NP_061218.2| golgi autoantigen, golgin
subfamily a, 4 [Mus musculus]
         (2238 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

29793                                                                  33   1.9  
01241                                                                  31   4.6  
>29793
          Length = 1088

 Score = 32.7 bits (73), Expect = 1.9,   Method: Compositional matrix adjust.
 Identities = 26/81 (32%), Positives = 44/81 (54%), Gaps = 1/81 (1%)
 Frame = +2

Query: 790 EHLRERQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVL 849
           E + E+Q ++QDL + +Q    E +  L ++ LLH++  +     G  EEQL+       
Sbjct: 575 EEVDEKQKQIQDLTSDVQNILHEKESILTQVQLLHTKADSEALARGIAEEQLS------- 733

Query: 850 DLETEKSLLTKQVVE-METHK 869
           D+E EK++L  ++ E M  HK
Sbjct: 734 DVEKEKTMLELEIKELMSRHK 796
>01241
          Length = 1158

 Score = 31.2 bits (69), Expect = 4.6,   Method: Composition-based stats.
 Identities = 18/61 (29%), Positives = 29/61 (47%)
 Frame = -3

Query: 236 EEKDQYISVLQTQVSLLKQRLQNGPMNVDAPKPLPPGELQAEVHGDTEKMEGVGEPVGGG 295
           E +   +  +QT + +   R+  G +  DA    PPG+   + HGD  +   +G  VGG 
Sbjct: 640 EARGSAVCPIQT-LGVKDSRVLRGQVFSDAVHTSPPGQYMIDSHGDDRQGVAIGSDVGGD 464

Query: 296 T 296
           T
Sbjct: 463 T 461
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31542904|ref|NP_058090.2| golgi SNAP receptor complex
member 1 [Mus musculus]
         (250 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

35962                                                                  29   1.9  
18343                                                                  28   4.5  
>35962
          Length = 554

 Score = 28.9 bits (63), Expect = 1.9,   Method: Compositional matrix adjust.
 Identities = 19/58 (32%), Positives = 30/58 (51%), Gaps = 2/58 (3%)
 Frame = +1

Query: 83  GVNDKMAEYTHSAGVPSL--NAALMHTLQRHRDILQDYTHEFHKTKANFTAIRERENL 138
           GV    A   H+   P    ++AL H   RHR +LQD+ HE  K++A  + + ++  L
Sbjct: 1   GVRI*RAHRVHARSAPDTAGHSALQHL--RHRRLLQDHVHEG*KSRAVVSVVSDQRAL 168
>18343
          Length = 461

 Score = 27.7 bits (60), Expect = 4.5,   Method: Compositional matrix adjust.
 Identities = 21/61 (34%), Positives = 30/61 (49%), Gaps = 1/61 (1%)
 Frame = +1

Query: 7   NYWEDLRKQARQLENELDLKLVSFSKLCTSYSHSGSRDGGRDRYSSDTTPLLN-GSSQDR 65
           N W D+  Q  Q +  L  +L    KLCT+ S    R        + TTP L+ GS+++R
Sbjct: 94  NTWSDVLNQNTQQKEHLVNQL*QTKKLCTNTSSMKCRRATL----THTTPTLSAGSARER 261

Query: 66  M 66
           M
Sbjct: 262 M 264
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|110665705|ref|NP_034374.2| Friend virus
susceptibility 1 [Mus musculus]
         (459 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

18645                                                                  30   2.0  
>18645
          Length = 477

 Score = 30.0 bits (66), Expect = 2.0,   Method: Compositional matrix adjust.
 Identities = 26/82 (31%), Positives = 34/82 (41%), Gaps = 2/82 (2%)
 Frame = -2

Query: 53  SFSSGKELNDSVYHTFEHFCKI--RDYDAVGELLLAFLDKVTKERDQFRDEISQLRMHIN 110
           SF     LN S++  F   C +  R    V   LL FL  V      FRD I +L  H +
Sbjct: 248 SFYRRPSLNPSIFSLFVTRCLVVKRFQHCV---LLKFLMCVCMI*KAFRDIIVRLSFHTS 78

Query: 111 DLKASKCVLGETLLSYRHRIEV 132
            +  S+   GE     RH+  V
Sbjct: 77  SVTMSRFCFGEAFRRKRHQYHV 12
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|23956096|ref|NP_062363.1| USO1 homolog, vesicle
docking protein [Mus musculus]
         (959 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

04767                                                                  31   2.0  
>04767
          Length = 477

 Score = 31.2 bits (69), Expect = 2.0,   Method: Composition-based stats.
 Identities = 15/39 (38%), Positives = 22/39 (56%)
 Frame = +1

Query: 828 SVPVEGESEHVSAAKTTDVEGRLSALLQETKELKNEIKA 866
           +VP+E    H  A  T D E   +A +Q TKE +N++ A
Sbjct: 229 NVPLEPLWRHNCAQGTKDFEANTAAAIQATKERRNQLSA 345
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|42733606|ref|NP_658906.1| crystallin, gamma B [Mus
musculus]
         (175 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

12591                                                                  28   2.0  
05309                                                                  27   3.3  
12326                                                                  27   3.9  
02001                                                                  26   8.5  
00635                                                                  26   9.0  
>12591
          Length = 400

 Score = 28.1 bits (61), Expect = 2.0,   Method: Compositional matrix adjust.
 Identities = 11/38 (28%), Positives = 22/38 (57%)
 Frame = +1

Query: 77  RSCCLIPQHSGTYRMRIYEKDDFRGQMSEITDDCLSLQ 114
            S  +I +HS      I+ KD+++ Q+S++   C+ L+
Sbjct: 205 NSIDIIHEHSNEIITYIFAKDEYKNQISQVMAICIFLE 318
>05309
          Length = 2347

 Score = 27.3 bits (59), Expect = 3.3,   Method: Compositional matrix adjust.
 Identities = 13/38 (34%), Positives = 17/38 (44%)
 Frame = -2

Query: 72  FSDSIRSCCLIPQHSGTYRMRIYEKDDFRGQMSEITDD 109
           F D +  CC  P H+G            +GQ+S IT D
Sbjct: 870 FIDGVHVCCCGPHHAG-----------LKGQLSTITTD 790
>12326
          Length = 519

 Score = 26.9 bits (58), Expect = 3.9,   Method: Compositional matrix adjust.
 Identities = 14/38 (36%), Positives = 19/38 (50%), Gaps = 6/38 (15%)
 Frame = +2

Query: 56  YFLRRGEYPDYQQWMGFSDSIRSCC------LIPQHSG 87
            FLR G   D+Q+W+   + + SCC      L P H G
Sbjct: 257 VFLRNGPPCDWQRWICGGERLGSCCI*LP*VLCPWHPG 370
>02001
          Length = 4146

 Score = 26.2 bits (56), Expect = 8.5,   Method: Compositional matrix adjust.
 Identities = 12/40 (30%), Positives = 20/40 (50%)
 Frame = +1

Query: 99   FRGQMSEITDDCLSLQDRFHFSEIHSLNVMEGCWVLYEMP 138
            FR  + +IT  C+    +FH     SL + +  W  ++MP
Sbjct: 3412 FR*DVGQITRRCVLFVAKFHNGANESLMLSDNFWQFWKMP 3531
>00635
          Length = 1039

 Score = 25.8 bits (55), Expect = 9.0,   Method: Compositional matrix adjust.
 Identities = 14/32 (43%), Positives = 19/32 (59%)
 Frame = -3

Query: 24  PNLQTYFSRCNSVRVDSGCWMLYERPNYQGHQ 55
           PN+ T+FSR  S+R ++  W     PN Q HQ
Sbjct: 896 PNVNTHFSRN*SMRHNNVLWC---SPNTQQHQ 810
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|83921574|ref|NP_033174.2| SEC8 [Mus musculus]
         (975 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

28350                                                                  31   2.0  
04416                                                                  30   5.2  
>28350
          Length = 3385

 Score = 31.2 bits (69), Expect = 2.0,   Method: Compositional matrix adjust.
 Identities = 27/77 (35%), Positives = 39/77 (50%), Gaps = 4/77 (5%)
 Frame = -3

Query: 190  LVLIEELHRHLYIKSTS--RVVQ--RNKEKGKMSSHGKDPSPGPLIDVSNIPTPRKFLDA 245
            L L ++ H  LY+ ST   R V+  RNKE   +S +    SPGP +   NI      ++ 
Sbjct: 2687 LSLCQQSHNELYLNSTK*YRKVKYKRNKEHKSVSIYRSGKSPGPCLVF*NI------INF 2526

Query: 246  SQYSAAGGSSVREMNLQ 262
            S++SA   SS    NL+
Sbjct: 2525 SKFSA*QPSSGSFYNLK 2475
>04416
          Length = 1967

 Score = 30.0 bits (66), Expect = 5.2,   Method: Compositional matrix adjust.
 Identities = 11/18 (61%), Positives = 16/18 (88%)
 Frame = +2

Query: 189 HLVLIEELHRHLYIKSTS 206
           H+VLI+E+H H Y+K+TS
Sbjct: 431 HIVLIKEMHVHCYLKTTS 484
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|113204613|ref|NP_034967.2| microtubule-associated
protein 6 isoform 1 [Mus musculus]
         (906 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

18799                                                                  31   2.1  
>18799
          Length = 480

 Score = 31.2 bits (69), Expect = 2.1,   Method: Compositional matrix adjust.
 Identities = 12/28 (42%), Positives = 18/28 (64%)
 Frame = +2

Query: 122 DYRAWKVQRPEPSCRPRSEYQPSDAPFE 149
           D++ W + R +P  RP  +Y P+DAPF 
Sbjct: 293 DFKPWDINRVQPVMRP--DYHPNDAPFH 370

 Score = 28.9 bits (63), Expect = 9.9,   Method: Compositional matrix adjust.
 Identities = 13/32 (40%), Positives = 17/32 (53%)
 Frame = +2

Query: 134 SCRPRSEYQPSDAPFERETQYQKDFRAWPLPR 165
           S +P      SDAPFE  T ++ D+R W   R
Sbjct: 23  SFKPEGRAVASDAPFEDGTTFKDDYRRWTTER 118
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|159110787|ref|NP_032661.2| microtubule-associated
protein 7 [Mus musculus]
         (730 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

12731                                                                  31   2.1  
01583                                                                  31   2.1  
>12731
          Length = 961

 Score = 30.8 bits (68), Expect = 2.1,   Method: Compositional matrix adjust.
 Identities = 12/27 (44%), Positives = 15/27 (55%)
 Frame = -3

Query: 27  YKVQEKRTAPSRPTSTVSGQTSNHSGN 53
           YK+ E    P  PT+T SG  SN+  N
Sbjct: 845 YKIMEYEIGPQHPTATYSGDCSNYISN 765
>01583
          Length = 1185

 Score = 30.8 bits (68), Expect = 2.1,   Method: Compositional matrix adjust.
 Identities = 16/35 (45%), Positives = 23/35 (65%)
 Frame = -2

Query: 224 SVVSRLLTPTHSFLARSKSTAALSGDTASCSPIIM 258
           S++S +  P   FLARSK++AA     A CSP+I+
Sbjct: 578 SLISSVTLPDEQFLARSKASAA---SRACCSPVIL 483
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|19526936|ref|NP_598498.1| LanC (bacterial lantibiotic
synthetase component C)-like 2 [Mus musculus]
         (450 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

00413                                                                  30   2.1  
00375                                                                  29   3.2  
18978                                                                  29   4.0  
>00413
          Length = 490

 Score = 30.0 bits (66), Expect = 2.1,   Method: Compositional matrix adjust.
 Identities = 17/55 (30%), Positives = 28/55 (50%), Gaps = 7/55 (12%)
 Frame = +1

Query: 337 VFKEEKYLKEA------MECSDVIWQRGLLRKGYGICHGTSGNGYS-FLSLYRLT 384
           +F    YL +A      ++   ++WQ GL+ KG+     T   G + +L L+RLT
Sbjct: 79  IFNASVYLNKAFMNEITLKLLKILWQNGLVSKGWEFKPSTQPPGVNRYLVLFRLT 243
>00375
          Length = 1080

 Score = 29.3 bits (64), Expect = 3.2,   Method: Compositional matrix adjust.
 Identities = 17/55 (30%), Positives = 27/55 (49%), Gaps = 7/55 (12%)
 Frame = +3

Query: 337 VFKEEKYLKEAM------ECSDVIWQRGLLRKGYGICHGTSGNGYS-FLSLYRLT 384
           +F    YL +A       +   ++WQ GL+ KG+     T   G + +L L+RLT
Sbjct: 78  IFNASVYLNKAFMNEITXKLLKILWQNGLVSKGWEFKPSTQPPGVNXYLVLFRLT 242
>18978
          Length = 732

 Score = 28.9 bits (63), Expect = 4.0,   Method: Compositional matrix adjust.
 Identities = 16/45 (35%), Positives = 23/45 (51%)
 Frame = +1

Query: 295 YVRHKKFRSGNYPSSLSNETDRLVHWCHGAPGVIHVLLQAYQVFK 339
           +  H  F  G++   L +  + LVH  HG  GVI  LL   Q+F+
Sbjct: 259 WFFHFGFVIGHFKDPLGHSINDLVHVAHGRSGVIRCLLFLAQLFE 393
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|22164798|ref|NP_033176.2| selenium binding protein 1
[Mus musculus]
         (472 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

25991                                                                  30   2.1  
38631                                                                  30   2.3  
>25991
          Length = 847

 Score = 30.0 bits (66), Expect = 2.1,   Method: Compositional matrix adjust.
 Identities = 17/66 (25%), Positives = 29/66 (43%), Gaps = 14/66 (21%)
 Frame = -1

Query: 53  SPQYSQVIHRLPMPYLKDELHHSGWNTCSSCFGDSTK--------------SRNKLILPG 98
           +P+  + +  L + Y  +E+    W   ++ FGD T                RNKL +PG
Sbjct: 235 TPEEQKRLDELLVQYPPEEVEARRWRKIAAAFGDRTPQQIASRVQKYFEKLERNKLPVPG 56

Query: 99  LISSRI 104
            + +RI
Sbjct: 55  RVPNRI 38
>38631
          Length = 720

 Score = 30.0 bits (66), Expect = 2.3,   Method: Compositional matrix adjust.
 Identities = 18/85 (21%), Positives = 35/85 (41%), Gaps = 5/85 (5%)
 Frame = -2

Query: 135 SLHTSHCLASGEVMVSTLGDLQGNGKGSFVLLDGETFEVKGTWEK-----PGDAAPMGYD 189
           +L+T+HC  + +      G     G+    L    +  +  +  +     P +   +   
Sbjct: 329 TLNTAHCSNTRQDSRIKRGQNSSKGRMCNALQTFHSQAMSNSMRRLHTTGPAEGLVLNLH 150

Query: 190 FWYQPRHNVMVSTEWAAPNVFKDGF 214
            ++QP H+V   T  +  N+F DGF
Sbjct: 149 HYFQPIHDVPSQTPLSMTNIFTDGF 75
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|10946620|ref|NP_067291.1| cell cycle exit and
neuronal differentiation 1 [Mus musculus]
         (149 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

12977                                                                  27   2.2  
>12977
          Length = 852

 Score = 27.3 bits (59), Expect = 2.2,   Method: Compositional matrix adjust.
 Identities = 15/46 (32%), Positives = 20/46 (43%), Gaps = 5/46 (10%)
 Frame = +2

Query: 102 DGAEEDESNTGGRGPWPCE-----NLTPLLVAGGVAVATIALILGV 142
           DG E      GG+G W C       LT ++   GV +  I  +L V
Sbjct: 683 DGLEFLRHEIGGKGLWACSLLCNGTLTVIIDTCGVQIMYICEVLNV 820
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|11528504|ref|NP_071301.1| family with sequence
similarity 129, member A [Mus musculus]
         (725 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

20600                                                                  31   2.2  
>20600
          Length = 1020

 Score = 30.8 bits (68), Expect = 2.2,   Method: Compositional matrix adjust.
 Identities = 13/36 (36%), Positives = 17/36 (47%)
 Frame = +2

Query: 676 DSSALGMDTEQVNDTHEHACQWLVEDTLSTDILAVH 711
           D+      T  +NDTH H C  L E T +  +  VH
Sbjct: 65  DTCVYARYTHMLNDTHTHLCTHLCEHTRTCTLFHVH 172
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|188528613|ref|NP_071306.2| glia maturation factor,
beta [Mus musculus]
         (142 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

13353                                                                  27   2.2  
05431                                                                  27   3.1  
18320                                                                  25   9.0  
>13353
          Length = 1027

 Score = 27.3 bits (59), Expect = 2.2,   Method: Compositional matrix adjust.
 Identities = 17/49 (34%), Positives = 24/49 (48%), Gaps = 5/49 (10%)
 Frame = +2

Query: 56  ELKDELPERQPRFIVYSYKYQHDDGRVSYPLCFIFSSP-----VGCKPE 99
           ELK  L E   R++V++ K  + DG+V   L  +  SP      G  PE
Sbjct: 659 ELKQVLREAGGRYVVFNNKESNPDGQVEKLLALLEKSPTSGSDTGLSPE 805
>05431
          Length = 1146

 Score = 26.9 bits (58), Expect = 3.1,   Method: Compositional matrix adjust.
 Identities = 12/35 (34%), Positives = 21/35 (60%)
 Frame = +3

Query: 81  RVSYPLCFIFSSPVGCKPEQQMMYAGSKNKLVQTA 115
           R+SY L F+F         +Q+++ GSK ++ +TA
Sbjct: 222 RLSYNLNFVFKKV*SWMLPEQLVFRGSKREMARTA 326
>18320
          Length = 450

 Score = 25.4 bits (54), Expect = 9.0,   Method: Compositional matrix adjust.
 Identities = 16/57 (28%), Positives = 27/57 (47%)
 Frame = -2

Query: 63  ERQPRFIVYSYKYQHDDGRVSYPLCFIFSSPVGCKPEQQMMYAGSKNKLVQTAELTK 119
           ER+    V+S   QH D  +   + F     V      Q++ AGS+++ +   +LTK
Sbjct: 359 ERERTHRVWSDPNQHMDHFIYNDILFAAVDVVHLMQNGQLLAAGSRDRYLTLLDLTK 189
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|94392296|ref|XP_001004080.1| PREDICTED: similar to
Charged multivesicular body protein 6 (Chromatin-modifying protein 6)
isoform 1 [Mus musculus]
         (103 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

27653                                                                  27   2.2  
21782                                                                  25   6.0  
07726                                                                  25   7.8  
>27653
          Length = 876

 Score = 26.9 bits (58), Expect = 2.2,   Method: Compositional matrix adjust.
 Identities = 24/93 (25%), Positives = 42/93 (45%), Gaps = 14/93 (15%)
 Frame = +3

Query: 6   GLQVGNECLNKMHQVMS-IEEVERILDETQEAV-------------EYQRQIDELLAGNF 51
            L   N  ++K+H +M  I E + +  E  +A+             + +R++DEL   NF
Sbjct: 246 NLHTKNMDVDKVHDMMDDIAEQQDVAREISDAISNPVAFGADLDDEDLERELDELEQENF 425

Query: 52  TQEDEDAILEELNAITQEQMELPEVPSEPLPDR 84
            +E        +  I +    LPE P+E LP++
Sbjct: 426 DKE--------IIGIPEPTHTLPEAPTEDLPEK 500
>21782
          Length = 805

 Score = 25.4 bits (54), Expect = 6.0,   Method: Compositional matrix adjust.
 Identities = 11/22 (50%), Positives = 15/22 (68%)
 Frame = -2

Query: 60  LEELNAITQEQMELPEVPSEPL 81
           LEEL A+ ++  ELP +PS P 
Sbjct: 318 LEELRAVHRQSPELPRLPSPPF 253
>07726
          Length = 461

 Score = 25.0 bits (53), Expect = 7.8,   Method: Compositional matrix adjust.
 Identities = 19/60 (31%), Positives = 30/60 (50%)
 Frame = +2

Query: 38 EYQRQIDELLAGNFTQEDEDAILEELNAITQEQMELPEVPSEPLPDRNPEAPAKARSRQA 97
          + +R++DEL   NF +E        +  I +    LPE P+E LP+       KA+ R+A
Sbjct: 23 DLERELDELEQENFDKE--------IIGIPEPTHTLPEAPTEDLPE-------KAKERKA 157
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|146231960|ref|NP_620570.2| chondroitin sulfate
proteoglycan 4 [Mus musculus]
         (2327 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

14963                                                                  32   2.3  
08472                                                                  32   3.0  
>14963
          Length = 1136

 Score = 32.3 bits (72), Expect = 2.3,   Method: Compositional matrix adjust.
 Identities = 22/65 (33%), Positives = 33/65 (50%), Gaps = 8/65 (12%)
 Frame = -1

Query: 1811 GPTGTSVAGPQTSEAFVITVRDV--NERPPQP-----QASIPLRVTRGSRAPVSRAQLSV 1863
            GP+  S +GP  +  + IT R++  N  PP P       S+PL+   G+ +PV   Q  V
Sbjct: 821  GPSCYSPSGPHFTSGWAITTRNII*NSGPPNP*FPKTCYSLPLQALSGNGSPVLHPQEEV 642

Query: 1864 V-DPD 1867
              DP+
Sbjct: 641  TPDPE 627
>08472
          Length = 537

 Score = 32.0 bits (71), Expect = 3.0,   Method: Compositional matrix adjust.
 Identities = 25/81 (30%), Positives = 40/81 (49%), Gaps = 2/81 (2%)
 Frame = +3

Query: 49  VDLLLQFSTSQPEALLLLAA-GQDDHLLLQLHSGCLQV-RLALGQKELKLQTPADTVLSD 106
           + + L FST +P+ LLL +   Q   L L L +G L++    LG     +Q PA   ++D
Sbjct: 144 IQISLNFSTIEPDGLLLWSQHNQLKFLGLGLENGHLKLASNLLGSNNDTVQAPASGFIAD 323

Query: 107 SAPHTVVLTVSDSWAVLSVDG 127
            A H   + +  +   L +DG
Sbjct: 324 GAWHGTSVLLDRNRLELQLDG 386
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|18875352|ref|NP_573468.1| arrestin 3, retinal [Mus
musculus]
         (381 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

10221                                                                  30   2.3  
>10221
          Length = 1323

 Score = 29.6 bits (65), Expect = 2.3,   Method: Compositional matrix adjust.
 Identities = 31/111 (27%), Positives = 51/111 (45%), Gaps = 5/111 (4%)
 Frame = +3

Query: 144  KSFCAENLEEKIPKSDSVQLVVRKVQ-----FSALEPGPGPSAQTIRSFFLSSQPLQLQA 198
            K++   N  E+ PK+  VQLV+ K Q      S L   P P     RS+      +  QA
Sbjct: 975  KNYNFPNKTERTPKTI*VQLVMYKTQRWKIYVSFLHSFPSP-----RSYL-----IHFQA 1124

Query: 199  WMDREVHYHGEAISVHVSINNYTNKVIRRIKIAVVQTTDVVLYSLDKYTKT 249
                  HYH +A +VH++  +  N +   + I ++     +L ++  YT+T
Sbjct: 1125 S*STPYHYHAQA-TVHLTQAH--NLIYTALNILILSANKFILNAIH-YTRT 1265
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6755304|ref|NP_035386.1| phosphatidylinositol
transfer protein, membrane-associated 2 [Mus musculus]
         (1281 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

02219                                                                  32   2.3  
>02219
          Length = 2649

 Score = 31.6 bits (70), Expect = 2.3,   Method: Compositional matrix adjust.
 Identities = 28/100 (28%), Positives = 44/100 (44%)
 Frame = +1

Query: 1175 FITDGYAAHLAQLKYNHRARPARNTATRMALRKGSFGLPGQSDFLRSRNHLLRTISAQPS 1234
            F  + Y+     L+   R  PA ++AT +     +       + ++S   LL+ IS+   
Sbjct: 55   FFLNSYSR---TLRPRSRISPASSSATLINFDNPTVQK-ALDNLIQSGPSLLKNISSPTP 222

Query: 1235 GPSHRHDRTQTQMDSEQRGQRSMSVAASCWGRAMAGRLEP 1274
             P HR D   T M +E   QRS  V       ++ G+LEP
Sbjct: 223  TPLHRDDPASTDMKAEPVHQRSSLV-------SVFGKLEP 321
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|94377272|ref|XP_979772.1| PREDICTED: hypothetical
protein LOC330286 [Mus musculus]
         (1940 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

14032                                                                  32   2.3  
>14032
          Length = 524

 Score = 32.0 bits (71), Expect = 2.3,   Method: Compositional matrix adjust.
 Identities = 21/71 (29%), Positives = 28/71 (39%), Gaps = 8/71 (11%)
 Frame = -3

Query: 259 EGAENLLFSSRIS--------VSQPSGNGMTQQPSVPLWEVSQPLVGVLATSSDRYPNET 310
           +G   L FSS+ S           P+G    + PS P W      VG   T +D YP  +
Sbjct: 510 DGGGKLTFSSQTSRRGTMVKTSDMPTGRSQVRTPSEPFWH-----VGFFRTQTDSYPEMS 346

Query: 311 TAWIEHPEEAI 321
             W +    AI
Sbjct: 345 VLWAQSETGAI 313
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|21624631|ref|NP_084099.1| hypothetical protein
LOC76976 [Mus musculus]
         (180 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

01380                                                                  28   2.4  
34173                                                                  26   9.7  
>01380
          Length = 1212

 Score = 27.7 bits (60), Expect = 2.4,   Method: Compositional matrix adjust.
 Identities = 12/23 (52%), Positives = 16/23 (69%)
 Frame = +1

Query: 23   TLGCILTTAFKDRSAPVRLHVSR 45
            TL  +L+T F D SAP R H+S+
Sbjct: 1144 TLDDVLSTEFTDESAPRRRHLSK 1212
>34173
          Length = 481

 Score = 25.8 bits (55), Expect = 9.7,   Method: Compositional matrix adjust.
 Identities = 12/24 (50%), Positives = 14/24 (58%)
 Frame = -3

Query: 94  STKSNAVNQVVLWDKILLRGENPK 117
           ST +N  N    + KI LRG NPK
Sbjct: 89  STHTNTXNTARHFSKIGLRGGNPK 18
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31980821|ref|NP_058586.2| dynactin 3 [Mus musculus]
         (186 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

08560                                                                  28   2.4  
06740                                                                  26   7.9  
>08560
          Length = 544

 Score = 28.1 bits (61), Expect = 2.4,   Method: Compositional matrix adjust.
 Identities = 19/58 (32%), Positives = 29/58 (50%), Gaps = 2/58 (3%)
 Frame = +1

Query: 118 AVPEHAARLQRLAQIHIQQQDQCVAITEESKALLEGY--NKTTMLLSKQFVQWDELLC 173
           A  EH+ R + L   +  Q +QCV    E+   LEG   +K ++ LS  F++    LC
Sbjct: 64  AFHEHSRRQRNLLM*NCHQAEQCVCAANETS--LEGTP*HKISLCLSSTFLKHAAKLC 231
>06740
          Length = 1867

 Score = 26.2 bits (56), Expect = 7.9,   Method: Compositional matrix adjust.
 Identities = 13/38 (34%), Positives = 22/38 (57%)
 Frame = +3

Query: 146  ESKALLEGYNKTTMLLSKQFVQWDELLCQLEAAKQVKP 183
            +S ++  G  +T+  L+   V+ + LLC+LEA K   P
Sbjct: 1266 QSISINTGNVQTSWSLNNDTVKRESLLCRLEAGKSYTP 1379
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|114158691|ref|NP_598566.3| COP9 signalosome subunit 8
[Mus musculus]
         (209 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

25714                                                                  28   2.5  
>25714
          Length = 442

 Score = 28.1 bits (61), Expect = 2.5,   Method: Compositional matrix adjust.
 Identities = 15/49 (30%), Positives = 26/49 (53%)
 Frame = +1

Query: 23 QELEAPGGIATPPVYGQLLALYLLQNDMNNARYLWKRIPPAIKSANSEL 71
          Q     GG+A    Y ++L + + +N +      +K+IPPA+K  +S L
Sbjct: 52 QNSSKSGGLA----YIKMLGILMFENKIVPKIKHFKKIPPAVKDLHSRL 186
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|160333480|ref|NP_659050.2| transmembrane protein 143
[Mus musculus]
         (458 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

06028                                                                  30   2.5  
30341                                                                  28   9.5  
>06028
          Length = 1358

 Score = 29.6 bits (65), Expect = 2.5,   Method: Compositional matrix adjust.
 Identities = 12/40 (30%), Positives = 22/40 (55%)
 Frame = +2

Query: 175 LVVHHPQDEVQVTINLDQYIYIQFWALGQRVGQMPHKSSV 214
           L + HP+ + +  INL  Y YI  + L Q +   P ++++
Sbjct: 812 LQLKHPKRKNKAYINLSLYAYIYIYILAQILNAFPKRNNI 931
>30341
          Length = 590

 Score = 27.7 bits (60), Expect = 9.5,   Method: Compositional matrix adjust.
 Identities = 19/60 (31%), Positives = 25/60 (41%), Gaps = 1/60 (1%)
 Frame = +1

Query: 68  RERFIPFSKEQLLRLLIQEFHSSPAERAALEAFSAHVDFCTLFHYHQLLA-RLQALYDPI 126
           R    P   + +  L  Q F S    R AL      VD+   +H HQ    RL+  YDP+
Sbjct: 1   RTHLSPRDNQYVASLGHQSFPSHSTPRMALSRDDTEVDYGAFYHPHQADPHRLEREYDPL 180
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|10181182|ref|NP_065651.1| transmembrane protein 27
[Mus musculus]
         (222 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

07927                                                                  28   2.6  
>07927
          Length = 1131

 Score = 28.5 bits (62), Expect = 2.6,   Method: Compositional matrix adjust.
 Identities = 23/81 (28%), Positives = 34/81 (41%), Gaps = 2/81 (2%)
 Frame = +3

Query: 16  LCHPDAENAFKVRLSIRAALGDKAYVWDTDQEYLFRAMVAFSMRKVPNREA--TEISHVL 73
           LC P+AE     ++  + + G K Y   T    L        +R+  NR    TE  H+ 
Sbjct: 723 LCPPEAEAFVLFKMPKKPSPGTKTYK*TTLFILLVLVTHEHKVRQNTNRPKCDTEHRHIK 902

Query: 74  LCNITQRVSFWFVVTDPSNNY 94
                 RVSF+F V +   N+
Sbjct: 903 QIKHKARVSFFFTVQNALYNF 965
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|189491678|ref|NP_081988.3| discs large
homolog-associated protein 1 isoform 2 [Mus musculus]
         (934 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

10557                                                                  31   2.6  
02882                                                                  31   3.0  
36618                                                                  30   3.1  
>10557
          Length = 1102

 Score = 30.8 bits (68), Expect = 2.6,   Method: Composition-based stats.
 Identities = 14/33 (42%), Positives = 21/33 (63%), Gaps = 1/33 (3%)
 Frame = +3

Query: 879 WDMLQLSIENISMKFDELHQLK-ANNWKQMDPL 910
           WD L LS++ IS+ FD+L+      +W Q+D L
Sbjct: 156 WDYLSLSLQKISVHFDQLYTYHFFKHWIQVDLL 254
>02882
          Length = 2876

 Score = 30.8 bits (68), Expect = 3.0,   Method: Compositional matrix adjust.
 Identities = 14/33 (42%), Positives = 21/33 (63%), Gaps = 1/33 (3%)
 Frame = -3

Query: 879 WDMLQLSIENISMKFDELHQLK-ANNWKQMDPL 910
           WD L LS++ IS+ FD+L+      +W Q+D L
Sbjct: 699 WDYLSLSLQKISVHFDQLYTYHFFKHWIQVDLL 601
>36618
          Length = 157

 Score = 30.4 bits (67), Expect = 3.1,   Method: Composition-based stats.
 Identities = 17/35 (48%), Positives = 24/35 (68%), Gaps = 2/35 (5%)
 Frame = +2

Query: 828 LPEDILGKIRTAVGSAQLLMAQ--KFYQFRELCEE 860
           L E++ G+IRT V  AQLLM +  KF+QF  L ++
Sbjct: 2   LTEEVEGQIRTTVCQAQLLMDKKGKFHQFAGLVDK 106
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|9506541|ref|NP_062378.1| diacylglycerol kinase,
epsilon [Mus musculus]
         (564 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

23732                                                                  30   2.6  
13069                                                                  28   10.0 
>23732
          Length = 981

 Score = 30.0 bits (66), Expect = 2.6,   Method: Compositional matrix adjust.
 Identities = 26/101 (25%), Positives = 51/101 (50%)
 Frame = -1

Query: 308 GTGNDLSNTLGWGTGYAGEIPVAQVLRNVMEADGIKLDRWKVQVTNKGYYNLRKPKEFTM 367
           G+G DL           G+I + +++  + E   + L + ++Q T+K Y  L     F++
Sbjct: 696 GSGEDL-----------GKIVIIKIVLPISEI*TVDLSKVEMQHTHK-YRRL-----FSL 568

Query: 368 NNYFSVGPDALMALNFHAHREKAPSLFSSRILNKAVYLFYG 408
            NY +    +L++    +++     +F+SRIL  A+Y+FY 
Sbjct: 567 QNYLN---KSLISSPTFSYK-----MFNSRILTTALYMFYS 469
>13069
          Length = 1129

 Score = 28.1 bits (61), Expect = 10.0,   Method: Compositional matrix adjust.
 Identities = 12/34 (35%), Positives = 19/34 (55%)
 Frame = -1

Query: 109 IMLKNDKAADAMPHHWIRGNVPLCSYCVFCRQQC 142
           I+LK+ + A +    W+R    +C  CVF  Q+C
Sbjct: 493 IILKSQQFAASFSKPWLRTISNVCECCVFFSQEC 392
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6755997|ref|NP_035846.1| Wolfram syndrome 1 protein
homolog [Mus musculus]
         (890 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

19465                                                                  31   2.7  
27955                                                                  30   3.3  
05014                                                                  30   3.9  
11391                                                                  29   8.7  
00679                                                                  29   9.3  
>19465
          Length = 500

 Score = 30.8 bits (68), Expect = 2.7,   Method: Composition-based stats.
 Identities = 23/81 (28%), Positives = 36/81 (44%)
 Frame = -2

Query: 613 RWWTKANFSVMGMVKSLTKSSMVKLILVWLTAILLFCWFYVYRSEGMKVYNSTLTWQQYG 672
           R WT   + + G   S  +SS ++  L WL +    CW +++R     VY S L  +  G
Sbjct: 475 RDWTIGEYRMAGTT-SAERSSPIRSTLPWLESR*ERCWHWMHRLNVGLVYPSPLRSRH*G 299

Query: 673 FLCGPRAWKETNMARTQILCS 693
             C    W+ T+    Q  C+
Sbjct: 298 -CCQSYPWERTSPPHHQT*CN 239
>27955
          Length = 2509

 Score = 30.4 bits (67), Expect = 3.3,   Method: Compositional matrix adjust.
 Identities = 23/70 (32%), Positives = 34/70 (48%), Gaps = 5/70 (7%)
 Frame = -1

Query: 689  QILCSHLE--GHRVTWTGRFKYVRVTEIDNSAESAINMLPF---FLGDWMRCLYGEAYPS 743
            ++LC  L+  G RV+W+         +   S     + LPF   + GDW    YG AY S
Sbjct: 2194 RVLCPGLDYGGRRVSWS---------DCPLSGGRLHSSLPFQEHYPGDWG---YGRAYFS 2051

Query: 744  CSSGNTSTAE 753
            C+S +T T +
Sbjct: 2050 CTSAHTCTGD 2021
>05014
          Length = 1020

 Score = 30.0 bits (66), Expect = 3.9,   Method: Composition-based stats.
 Identities = 19/56 (33%), Positives = 27/56 (48%), Gaps = 6/56 (10%)
 Frame = +3

Query: 324 HHINALIF------FFIISNLTIDFFAFFIPLVVFYLSFVSMVICTLKVFQDSKAW 373
           HH+  + F      F I+SNL I    F   + +FY S  S V+C   VF +S  +
Sbjct: 810 HHLLCVCFYKDISSFLILSNLFIFCVCF*SQMFIFYFSSPSFVLCV*IVFYNSNTF 977
>11391
          Length = 1866

 Score = 28.9 bits (63), Expect = 8.7,   Method: Composition-based stats.
 Identities = 16/55 (29%), Positives = 25/55 (45%), Gaps = 2/55 (3%)
 Frame = -3

Query: 590  WFLS--LDLTKIMVTTVICGVPLLFRWWTKANFSVMGMVKSLTKSSMVKLILVWL 642
            WF     D   I  T       +LFR W++ N + +G +  L    + KLI +W+
Sbjct: 1792 WFTQDLSDCENINYTEKFSETKILFRIWSQRNITPLGRIAILKSLILSKLIHLWI 1628
>00679
          Length = 1045

 Score = 28.9 bits (63), Expect = 9.3,   Method: Composition-based stats.
 Identities = 15/34 (44%), Positives = 18/34 (52%)
 Frame = +2

Query: 333 FIISNLTIDFFAFFIPLVVFYLSFVSMVICTLKV 366
           FII   TI FF F    V FYL   S++IC   +
Sbjct: 134 FIIDL*TILFFKFMFARVSFYLGMPSILICLFMI 235
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|9790019|ref|NP_062708.1| N-acylsphingosine
amidohydrolase 1 [Mus musculus]
         (394 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

08577                                                                  29   2.7  
03053                                                                  29   2.9  
07805                                                                  28   5.2  
30783                                                                  28   6.2  
18550                                                                  28   8.2  
>08577
          Length = 457

 Score = 29.3 bits (64), Expect = 2.7,   Method: Compositional matrix adjust.
 Identities = 15/50 (30%), Positives = 22/50 (44%)
 Frame = -3

Query: 341 NHTTQKNLSFATIYDVLSTKPVLNKLTVFTTLMDVTKGQFESHLRDCPDP 390
           +H    NL  AT  D     P+L+ +     L+D+T  Q +  L   P P
Sbjct: 386 HHAQSTNLPLATCSDKTKAYPILHPVRETKGLLDITPSQPKPQLSPPPRP 237
>03053
          Length = 2201

 Score = 29.3 bits (64), Expect = 2.9,   Method: Compositional matrix adjust.
 Identities = 15/50 (30%), Positives = 22/50 (44%)
 Frame = +2

Query: 341  NHTTQKNLSFATIYDVLSTKPVLNKLTVFTTLMDVTKGQFESHLRDCPDP 390
            +H    NL  AT  D     P+L+ +     L+D+T  Q +  L   P P
Sbjct: 1826 HHAQSTNLPLATCSDKTKAYPILHPVRETKGLLDITPSQPKPQLSPPPRP 1975
>07805
          Length = 783

 Score = 28.5 bits (62), Expect = 5.2,   Method: Compositional matrix adjust.
 Identities = 14/35 (40%), Positives = 22/35 (62%), Gaps = 1/35 (2%)
 Frame = +3

Query: 121 VTGIPLGEIISFNIFYE-LFTMCTSIITEDEKGHL 154
           VT +PL  +I FNIFY  L+ + + ++ E +  HL
Sbjct: 42  VTNLPLQMLIYFNIFYSPLWFIASIVVLEAKFSHL 146
>30783
          Length = 765

 Score = 28.1 bits (61), Expect = 6.2,   Method: Compositional matrix adjust.
 Identities = 12/34 (35%), Positives = 19/34 (55%)
 Frame = -2

Query: 354 YDVLSTKPVLNKLTVFTTLMDVTKGQFESHLRDC 387
           Y +  T P   K+   T++  VT  +F+SH R+C
Sbjct: 764 YKIPVTLPAKPKINAVTSVQRVTLPEFDSHWRNC 663
>18550
          Length = 632

 Score = 27.7 bits (60), Expect = 8.2,   Method: Compositional matrix adjust.
 Identities = 17/33 (51%), Positives = 20/33 (60%), Gaps = 1/33 (3%)
 Frame = -1

Query: 51  INLDLPPYKRWHEL-LAQKAPALRILVNSITSL 82
           + LDLPPY RWH L L   AP LR+ +    SL
Sbjct: 368 LALDLPPY-RWHMLALVLLAPCLRVSMARRMSL 273
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|13385560|ref|NP_080339.1| hypothetical protein
LOC67267 [Mus musculus]
         (136 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

21369                                                                  27   2.8  
23815                                                                  27   3.3  
22430                                                                  26   4.6  
16949                                                                  26   6.3  
05371                                                                  26   6.3  
09340                                                                  25   8.1  
12723                                                                  25   8.5  
>21369
          Length = 494

 Score = 26.9 bits (58), Expect = 2.8,   Method: Compositional matrix adjust.
 Identities = 14/32 (43%), Positives = 16/32 (50%), Gaps = 2/32 (6%)
 Frame = -1

Query: 49  EPEACDQMYESLARLHSNYYKH--KYPRPRDT 78
           EPE CDQ      RLH +   H  + PRP  T
Sbjct: 152 EPEPCDQSLPQDGRLHHHAAVHSQRXPRPAHT 57
>23815
          Length = 545

 Score = 26.6 bits (57), Expect = 3.3,   Method: Compositional matrix adjust.
 Identities = 14/29 (48%), Positives = 19/29 (65%), Gaps = 2/29 (6%)
 Frame = +2

Query: 53  CDQMY-ESLARLHSNYYKHKY-PRPRDTS 79
           CD MY +S A  HS+ Y+H Y P P +T+
Sbjct: 389 CDNMYTQSHAHAHSHTYRHNYSPPPPNTN 475
>22430
          Length = 497

 Score = 26.2 bits (56), Expect = 4.6,   Method: Compositional matrix adjust.
 Identities = 10/25 (40%), Positives = 17/25 (68%)
 Frame = +1

Query: 111 LQEKFAPTRPEEKHKAWTRVLSRPR 135
           +++KF  T  ++ H AW R+L+RP 
Sbjct: 124 IRDKFDDTF*QQHHGAWRRLLARPH 198
>16949
          Length = 1158

 Score = 25.8 bits (55), Expect = 6.3,   Method: Compositional matrix adjust.
 Identities = 12/25 (48%), Positives = 15/25 (60%), Gaps = 1/25 (4%)
 Frame = -2

Query: 53   CDQMY-ESLARLHSNYYKHKYPRPR 76
            CD MY +S A  HS+ Y+H Y  P 
Sbjct: 1079 CDNMYTQSHAHAHSHTYRHNYSPPH 1005
>05371
          Length = 1247

 Score = 25.8 bits (55), Expect = 6.3,   Method: Compositional matrix adjust.
 Identities = 12/25 (48%), Positives = 15/25 (60%), Gaps = 1/25 (4%)
 Frame = +2

Query: 53   CDQMY-ESLARLHSNYYKHKYPRPR 76
            CD MY +S A  HS+ Y+H Y  P 
Sbjct: 1010 CDNMYTQSHAHAHSHTYRHNYSPPH 1084
>09340
          Length = 888

 Score = 25.4 bits (54), Expect = 8.1,   Method: Compositional matrix adjust.
 Identities = 12/25 (48%), Positives = 15/25 (60%)
 Frame = -1

Query: 73  PRPRDTSFSGLSVEEYKLILSTDTL 97
           P P + SFS LSV E   +L  D+L
Sbjct: 354 PVPVENSFSALSVRETHQLLKADSL 280
>12723
          Length = 1100

 Score = 25.4 bits (54), Expect = 8.5,   Method: Compositional matrix adjust.
 Identities = 9/14 (64%), Positives = 13/14 (92%)
 Frame = +1

Query: 59  SLARLHSNYYKHKY 72
           +L ++H+NYYKHKY
Sbjct: 259 NLYKIHNNYYKHKY 300
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|19482160|ref|NP_082347.1| coactosin-like 1 [Mus
musculus]
         (142 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

20935                                                                  27   2.8  
09389                                                                  27   3.4  
>20935
          Length = 555

 Score = 26.9 bits (58), Expect = 2.8,   Method: Compositional matrix adjust.
 Identities = 18/85 (21%), Positives = 35/85 (41%), Gaps = 6/85 (7%)
 Frame = -2

Query: 43  ADYQHFIQQCTDDVRLFAFVRFTTGDAMSKRSKFALITWIGEDVSGLQRAKTGTDKTLVK 102
            +YQ +     + V ++ F+ F  GD++    + AL  W+G   +G            V 
Sbjct: 281 CEYQKYTYFXCESVCVYCFLNFAWGDSL----RMALSGWLGLKTTGFDLC--------VY 138

Query: 103 EVVQNFAKE------FVISDRKELE 121
           E +  +A E      +++  R +L 
Sbjct: 137 ECLYMYACECCSIHLYIVPARCKLH 63
>09389
          Length = 1218

 Score = 26.6 bits (57), Expect = 3.4,   Method: Compositional matrix adjust.
 Identities = 21/68 (30%), Positives = 31/68 (45%), Gaps = 1/68 (1%)
 Frame = +3

Query: 45  YQHFIQQCTDDVRLFAFVRFTTG-DAMSKRSKFALITWIGEDVSGLQRAKTGTDKTLVKE 103
           Y   +  C D +    F +   G  A SK   F LIT     ++ L+R+      +++K 
Sbjct: 144 YLRLVFACMDSMP--PFCQKPRGLTAQSKHLVFLLITXDNTSLA*LKRS*XSFMLSMIKV 317

Query: 104 VVQNFAKE 111
            VQNF KE
Sbjct: 318 SVQNFPKE 341
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|42476341|ref|NP_035432.3| retinoschisis 1 homolog
[Mus musculus]
         (224 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

12310                                                                  28   2.8  
03507                                                                  26   9.9  
>12310
          Length = 419

 Score = 28.1 bits (61), Expect = 2.8,   Method: Compositional matrix adjust.
 Identities = 13/39 (33%), Positives = 21/39 (53%)
 Frame = -2

Query: 160 RLNWIYYKDQTGNNRVFYGNSDRSSTVQNLLRPPIISRF 198
           +L+ +Y K QT  N   Y N+   ST+   +RP I  ++
Sbjct: 394 KLSLVYIKKQTSVNEPSYSNNSAESTLHYNIRPTIARKY 278
>03507
          Length = 1566

 Score = 26.2 bits (56), Expect = 9.9,   Method: Compositional matrix adjust.
 Identities = 28/106 (26%), Positives = 46/106 (43%), Gaps = 12/106 (11%)
 Frame = -1

Query: 35  QKACKCDCQ------VGANALWSAGA----TSLDCIPECPYHKPLGFESGEVTPD--QIT 82
           ++ CK  C+      VG   LW AG      S+   P  PY  P+G+   E  P+  ++ 
Sbjct: 681 REVCKSSCR*PDQLFVGICCLWQAGPERSPLSIKITP--PY--PVGWMDQE-GPEW*RVF 517

Query: 83  CSNPEQYVGWYSSWTANKARLNSQGFGCAWLSKYQDSSQWLQIDLK 128
           CSN +      ++W  +  R     FG  +LS+  ++  W  +  K
Sbjct: 516 CSNTDPSWKTGAAWVGDLYRFQMMSFGKQFLSRCINAGAWTGLITK 379
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31543247|ref|NP_075892.2| mesoderm development
candidate 2 [Mus musculus]
         (224 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

34762                                                                  28   2.9  
>34762
          Length = 570

 Score = 28.1 bits (61), Expect = 2.9,   Method: Compositional matrix adjust.
 Identities = 11/23 (47%), Positives = 18/23 (78%)
 Frame = -3

Query: 36  ATPPPRKKKDIRDYNDADMARLL 58
           +TPPPRKK++ + ++ A+M R L
Sbjct: 349 STPPPRKKREKKVHSVANMVRSL 281
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|7304929|ref|NP_038746.1| trafficking protein particle
complex 3 [Mus musculus]
         (180 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

14202                                                                  28   2.9  
>14202
          Length = 692

 Score = 27.7 bits (60), Expect = 2.9,   Method: Compositional matrix adjust.
 Identities = 14/40 (35%), Positives = 20/40 (50%)
 Frame = +3

Query: 68  CHDFRETADVIAKVAFKMYLGITPSITNWSPAGDEFSLIL 107
           CH   +    I  +  ++Y+ +T S   W   G EFSLIL
Sbjct: 405 CHKR*KLRTTIVVIMVQLYI-VTSSA*LWKSVGSEFSLIL 521
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|9910264|ref|NP_064429.1| histone cell cycle
regulation defective interacting protein 5 [Mus musculus]
         (199 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

32268                                                                  28   2.9  
33215                                                                  28   3.4  
>32268
          Length = 676

 Score = 27.7 bits (60), Expect = 2.9,   Method: Compositional matrix adjust.
 Identities = 14/29 (48%), Positives = 19/29 (65%)
 Frame = +2

Query: 140 GFEDGIVRLKLQGSCTSCPSSIITLKSGI 168
           GF+D +V   L  SC+S   SI+ LKSG+
Sbjct: 335 GFDDVVVIASLSASCSSRNLSILDLKSGL 421
>33215
          Length = 696

 Score = 27.7 bits (60), Expect = 3.4,   Method: Compositional matrix adjust.
 Identities = 14/33 (42%), Positives = 18/33 (54%)
 Frame = +1

Query: 126 RPTVQEDGGDVIYRGFEDGIVRLKLQGSCTSCP 158
           +P + ED  D + R F+D I RLK Q S    P
Sbjct: 598 KPKINEDPKDALLREFQDEINRLKNQLSEKGGP 696
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|119508431|ref|NP_573448.2| leucine zipper domain
protein [Mus musculus]
         (287 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

38077                                                                  28   3.0  
03143                                                                  28   3.5  
07126                                                                  27   8.5  
>38077
          Length = 531

 Score = 28.5 bits (62), Expect = 3.0,   Method: Compositional matrix adjust.
 Identities = 23/75 (30%), Positives = 34/75 (45%)
 Frame = +1

Query: 19  FRWLLHAEVHAVLRQLQDILKEASLRFTLPGPSTEGPAKQENFILGSCGTDQVKGTLTLQ 78
           FR L H+ + A   Q+ D ++EASL  T P   T+   + E  +L     D  +    + 
Sbjct: 43  FREL-HSLLQAREEQILDDIREASLNVTKPFQETKAFLQNEKIMLEMALADAXRA---MH 210

Query: 79  GDALSQADVNLKMPR 93
           G   S  D +L M R
Sbjct: 211 GSMHSLMDADLIMER 255
>03143
          Length = 1172

 Score = 28.5 bits (62), Expect = 3.5,   Method: Compositional matrix adjust.
 Identities = 16/38 (42%), Positives = 20/38 (52%), Gaps = 1/38 (2%)
 Frame = -3

Query: 30  VLRQLQDILKEASLRFTLPGP-STEGPAKQENFILGSC 66
           V + L +ILK  + R + PGP ST G  KQ      SC
Sbjct: 672 VKKWLNNILKVCTARVSAPGPSSTTGTQKQSKNFSTSC 559
>07126
          Length = 1917

 Score = 26.9 bits (58), Expect = 8.5,   Method: Compositional matrix adjust.
 Identities = 16/53 (30%), Positives = 24/53 (45%), Gaps = 4/53 (7%)
 Frame = +3

Query: 220  AGGAVLHSPG---AMFEWGSQRLEVSHVHKVECVIPWLNDALVYFTV-SLQLC 268
            A   V  + G     F +    L+  H+  ++C I W  D L+YF +  L LC
Sbjct: 1668 AHACVCMAVGNCNIFFIFFVCVLKKIHLISIKCYI*WFTDILIYFCIFCLTLC 1826
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|125490380|ref|NP_033534.2| solute carrier family 32
(GABA vesicular transporter), member 1 [Mus musculus]
         (525 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

09540                                                                  30   3.0  
02798                                                                  29   3.8  
00678                                                                  28   9.7  
04345                                                                  28   9.7  
>09540
          Length = 451

 Score = 29.6 bits (65), Expect = 3.0,   Method: Composition-based stats.
 Identities = 13/38 (34%), Positives = 22/38 (57%)
 Frame = +3

Query: 138 PYAILHGGYLGLFLIIFAAVVCCYTGKILIACLYEENE 175
           P+ ILHG +L    +IF A +C   G   +  +Y++N+
Sbjct: 72  PFQILHGPFLSGCEVIFFAKICDKKGHYCLDVIYKDNK 185
>02798
          Length = 566

 Score = 29.3 bits (64), Expect = 3.8,   Method: Compositional matrix adjust.
 Identities = 11/32 (34%), Positives = 20/32 (62%)
 Frame = -2

Query: 325 SLEGNMQQPSEFHCMMNWTHIAACVLKGLFAL 356
           + +  MQQP++++C  N  H+++  LK L  L
Sbjct: 475 TTDKKMQQPTKYYCWKNSVHLSSTCLKELCTL 380
>00678
          Length = 1387

 Score = 28.1 bits (61), Expect = 9.7,   Method: Compositional matrix adjust.
 Identities = 12/38 (31%), Positives = 20/38 (52%)
 Frame = -3

Query: 138 PYAILHGGYLGLFLIIFAAVVCCYTGKILIACLYEENE 175
           P+ ILHG +     +IF A +C   G   +  +Y++N 
Sbjct: 980 PFGILHGPFFSGCEVIFFAKICDKKGHYCLYVIYKDNN 867
>04345
          Length = 2153

 Score = 28.1 bits (61), Expect = 9.7,   Method: Compositional matrix adjust.
 Identities = 13/38 (34%), Positives = 21/38 (55%)
 Frame = +2

Query: 138 PYAILHGGYLGLFLIIFAAVVCCYTGKILIACLYEENE 175
           P+ ILHG +L    +IF A +C   G   +  +Y++N 
Sbjct: 566 PFEILHGPFLSGCEVIFFAKICDKKGHYCLYVIYKDNN 679
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6678674|ref|NP_032518.1| L-lactate dehydrogenase B
[Mus musculus]
         (334 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

10091                                                                  29   3.1  
05356                                                                  27   8.6  
>10091
          Length = 358

 Score = 28.9 bits (63), Expect = 3.1,   Method: Compositional matrix adjust.
 Identities = 13/47 (27%), Positives = 25/47 (53%)
 Frame = +1

Query: 225 SENWKEVHKMVVDSAYEVIKLKGYTNWAIGLSVADLIESMLKNLSRI 271
           S++   V KM++ +    +K  GY +  I + +A L   M+  +SR+
Sbjct: 127 SQHTLHVDKMILSTQRREVKSSGYRHMPIEIKIALLFPEMVGQMSRV 267
>05356
          Length = 2339

 Score = 27.3 bits (59), Expect = 8.6,   Method: Compositional matrix adjust.
 Identities = 16/61 (26%), Positives = 29/61 (47%), Gaps = 3/61 (4%)
 Frame = -1

Query: 124 QIVKYSPDCTIIVVSNPVDILTYVTWKLSG---LPKHRVIGSGCNLDSARFRYLMAEKLG 180
           ++V+ SP   I+ +   +    +V WKLS    +P  ++  +   LD  R R+    KL 
Sbjct: 212 RVVRASPCLLIVTLCTFITCTYFVDWKLSNGDKIPSVKIESTNAYLDKNRNRHTCETKLY 33

Query: 181 I 181
           +
Sbjct: 32  V 30
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|110626003|ref|NP_780304.2| COMM domain containing 2
[Mus musculus]
         (199 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

09704                                                                  28   3.2  
>09704
          Length = 790

 Score = 27.7 bits (60), Expect = 3.2,   Method: Compositional matrix adjust.
 Identities = 23/98 (23%), Positives = 43/98 (43%), Gaps = 10/98 (10%)
 Frame = +3

Query: 108 KEIRTILNELAPRLPSYH------SLEWRLDVQLASRSLRQQIK----PAVTIKLHLDQN 157
           KE +++LN  + R+ ++        + W+LD  L +  LRQQI+          L    N
Sbjct: 168 KERKSLLNR*SVRIVTWRRKYKFGKM*WQLDNALGNNVLRQQIR*KS*KLPCFFLSFTAN 347

Query: 158 GDHSTHFLQTDPATLLHLVQQLEQALEEMKTNHCRRVV 195
                 +  ++  T  +L+ + + A  E+K  HC   +
Sbjct: 348 SPSDLMYPSSEHVTYFYLIYEQQ*AC-ELKWCHCGWCI 458
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|13385810|ref|NP_080588.1| hypothetical protein
LOC67683 [Mus musculus]
         (198 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

02172                                                                  28   3.2  
18512                                                                  27   7.3  
>02172
          Length = 642

 Score = 27.7 bits (60), Expect = 3.2,   Method: Compositional matrix adjust.
 Identities = 15/43 (34%), Positives = 21/43 (48%)
 Frame = -2

Query: 91  ELKSESAKEKWRPFCLKFEGIVEDYNYGTLLRLDCSQGYTEEN 133
           ELK+ + ++K   +C K        NY T +R DC   YT  N
Sbjct: 173 ELKANAQEKK---YCAKHSPNQMIKNYSTNIRTDCQHTYTHTN 54
>18512
          Length = 749

 Score = 26.6 bits (57), Expect = 7.3,   Method: Compositional matrix adjust.
 Identities = 11/27 (40%), Positives = 18/27 (66%)
 Frame = +3

Query: 76  REIFETLRVDVLDPEELKSESAKEKWR 102
           REI  ++ V++ DP E +  S+ +KWR
Sbjct: 450 REIRRSVFVNIYDPNEARPLSSGKKWR 530
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|21426847|ref|NP_035193.1| phosphoprotein enriched in
astrocytes 15 isoform 2 [Mus musculus]
         (130 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

02200                                                                  27   3.2  
11190                                                                  25   7.3  
>02200
          Length = 2191

 Score = 26.6 bits (57), Expect = 3.2,   Method: Compositional matrix adjust.
 Identities = 15/47 (31%), Positives = 25/47 (53%)
 Frame = -3

Query: 21   EQLKSACKEDIPSEKSEEITTGSAWFSFLESHNKLDKDNLSYIEHIF 67
            E++ S  +E+IPS   EEI +     +F   HNK    N++  ++ F
Sbjct: 1505 EEIPSNAQEEIPSNAQEEIPSHIQ*TNFQAIHNKQFPSNINETDYFF 1365
>11190
          Length = 1060

 Score = 25.4 bits (54), Expect = 7.3,   Method: Compositional matrix adjust.
 Identities = 12/35 (34%), Positives = 21/35 (60%)
 Frame = +1

Query: 20  LEQLKSACKEDIPSEKSEEITTGSAWFSFLESHNK 54
           LE  + AC EDIP+E +  ++T +   S ++S + 
Sbjct: 664 LETEE*ACSEDIPNEGTTGMSTSAPMSSVMDSGSG 768
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|84000009|ref|NP_036144.2| G protein-regulated inducer
of neurite outgrowth 1 [Mus musculus]
         (932 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

11493                                                                  30   3.2  
02090                                                                  30   3.7  
>11493
          Length = 535

 Score = 30.4 bits (67), Expect = 3.2,   Method: Composition-based stats.
 Identities = 13/30 (43%), Positives = 18/30 (60%)
 Frame = -2

Query: 715 WDAGAPPPREDAGTQAGAQACVSVAVSPMS 744
           WD  +P PR  A   + A AC ++A+SP S
Sbjct: 258 WDLASPTPRIKAELTSAAPACYALAISPDS 169
>02090
          Length = 1841

 Score = 30.4 bits (67), Expect = 3.7,   Method: Composition-based stats.
 Identities = 12/28 (42%), Positives = 16/28 (57%)
 Frame = -3

Query: 715  WDAGAPPPREDAGTQAGAQACVSVAVSP 742
            WD   P PR  A   + A AC ++A+SP
Sbjct: 1677 WDLATPTPRIKAELTSSAPACYALAISP 1594
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|149265814|ref|XP_001002205.2| PREDICTED: hypothetical
protein LOC219189 [Mus musculus]
         (1905 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

20193                                                                  32   3.3  
>20193
          Length = 948

 Score = 31.6 bits (70), Expect = 3.3,   Method: Composition-based stats.
 Identities = 17/63 (26%), Positives = 29/63 (46%), Gaps = 5/63 (7%)
 Frame = +2

Query: 1092 RFLSFTEECTSWKFPLDEVNLIC---DIAVSHENGEQT--LYVAACNPVSLYFMNMTGKN 1146
            RF S T  C SW+FP   ++L+       + H N   +  L V     ++++F  + G+ 
Sbjct: 527  RFYSLTPNCLSWRFPFGYLSLLAWT*SQTLHHYNRSYSLKLLVTMSKNLAMHFTRVLGRK 706

Query: 1147 GFF 1149
              F
Sbjct: 707  QLF 715
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|21312546|ref|NP_081618.1| growth and
transformation-dependent protein [Mus musculus]
         (155 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

05669                                                                  27   3.3  
00341                                                                  27   3.3  
14015                                                                  26   5.4  
03430                                                                  26   5.8  
27257                                                                  26   6.6  
05933                                                                  26   7.3  
>05669
          Length = 466

 Score = 26.9 bits (58), Expect = 3.3,   Method: Compositional matrix adjust.
 Identities = 14/40 (35%), Positives = 21/40 (52%), Gaps = 2/40 (5%)
 Frame = +3

Query: 26  LRFTRNTDLKRINGFC--TKPQESPKTPTQSYRHGVPLHK 63
           +R +   DL R++     + P  SP TPT+ +   VPL K
Sbjct: 306 IRASSKKDLTRLDDSSNTSSPVNSPSTPTKEFLPKVPLPK 425
>00341
          Length = 1915

 Score = 26.9 bits (58), Expect = 3.3,   Method: Compositional matrix adjust.
 Identities = 10/31 (32%), Positives = 16/31 (51%)
 Frame = +1

Query: 42   TKPQESPKTPTQSYRHGVPLHKPTDFEKKIL 72
            ++P   P+TP    RHG P H+P   +  + 
Sbjct: 1729 SRPAWLPRTPAGCPRHGKPXHRPGSLQATVF 1821
>14015
          Length = 910

 Score = 26.2 bits (56), Expect = 5.4,   Method: Compositional matrix adjust.
 Identities = 14/36 (38%), Positives = 20/36 (55%)
 Frame = +1

Query: 38  NGFCTKPQESPKTPTQSYRHGVPLHKPTDFEKKILL 73
           N  CT    SPKTP  +Y+  VP     D++++I L
Sbjct: 559 NKXCTPGPPSPKTPQWAYKSLVP-QPVVDWDQQITL 663
>03430
          Length = 1294

 Score = 26.2 bits (56), Expect = 5.8,   Method: Compositional matrix adjust.
 Identities = 14/40 (35%), Positives = 21/40 (52%), Gaps = 2/40 (5%)
 Frame = -3

Query: 26  LRFTRNTDLKRINGFC--TKPQESPKTPTQSYRHGVPLHK 63
           +R +   DL R++     + P  SP TPT+ +   VPL K
Sbjct: 161 IRASSKKDLTRLDDSSNTSSPVNSPSTPTKEFLPKVPLPK 42
>27257
          Length = 378

 Score = 26.2 bits (56), Expect = 6.6,   Method: Compositional matrix adjust.
 Identities = 14/44 (31%), Positives = 23/44 (52%)
 Frame = -2

Query: 7   LRLAAGHCLRLYERNASSSLRFTRNTDLKRINGFCTKPQESPKT 50
           L + AG C R+   + +S L  TR++  + I+G C+    S  T
Sbjct: 296 LCVTAGQCSRITWYSFNSHLELTRSSVPRGISGSCSNRGNSANT 165
>05933
          Length = 1488

 Score = 25.8 bits (55), Expect = 7.3,   Method: Compositional matrix adjust.
 Identities = 11/32 (34%), Positives = 17/32 (53%)
 Frame = +1

Query: 28   FTRNTDLKRINGFCTKPQESPKTPTQSYRHGV 59
            F +N    R   FCT P    ++PT+ Y+H +
Sbjct: 1180 FAKNXGCLRRASFCTAPHVGVRSPTK-YQHAI 1272
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|21644587|ref|NP_660255.1| adaptor protein,
phosphotyrosine interaction, PH domain and leucine zipper containing 2
[Mus musculus]
         (662 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

08463                                                                  30   3.3  
>08463
          Length = 1422

 Score = 30.0 bits (66), Expect = 3.3,   Method: Compositional matrix adjust.
 Identities = 15/31 (48%), Positives = 19/31 (61%)
 Frame = -2

Query: 162 EIVKEVAAARRKQHLSSLQYYCALNALQYRK 192
            I+K    A +K  LSS+  + ALN LQYRK
Sbjct: 785 RIMKSTIHAAKKLLLSSIHLFFALNKLQYRK 693
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|22165404|ref|NP_079866.2| acyl-CoA thioesterase 11
[Mus musculus]
         (594 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

09814                                                                  30   3.3  
35317                                                                  29   4.5  
11870                                                                  29   5.1  
>09814
          Length = 1308

 Score = 29.6 bits (65), Expect = 3.3,   Method: Compositional matrix adjust.
 Identities = 19/51 (37%), Positives = 23/51 (45%), Gaps = 1/51 (1%)
 Frame = -2

Query: 44  RNPTEVQMSQLVLPCHTNHRGELSIGQLLKWIDTTACLSAE-RHAGCPCVT 93
           +NP     S+L L C    RG   I   L  +D T CL    R + CP VT
Sbjct: 788 KNPCSRSTSRLQLTC*CTGRGASRILSFLALLDNTPCLQLRTRPSSCPSVT 636
>35317
          Length = 341

 Score = 29.3 bits (64), Expect = 4.5,   Method: Composition-based stats.
 Identities = 13/33 (39%), Positives = 18/33 (54%)
 Frame = -2

Query: 44  RNPTEVQMSQLVLPCHTNHRGELSIGQLLKWID 76
           RN  E+QM   + P   +H  E   G+LL W+D
Sbjct: 103 RNDDEIQMFVFLYPQSKSHFTEYKKGKLLVWLD 5
>11870
          Length = 953

 Score = 29.3 bits (64), Expect = 5.1,   Method: Compositional matrix adjust.
 Identities = 16/40 (40%), Positives = 23/40 (57%), Gaps = 4/40 (10%)
 Frame = -3

Query: 58  CHTNHRGEL---SIGQLLKWIDTTACLSA-ERHAGCPCVT 93
           CH    G+    ++  L K+I T+ C +A ERH+G PC T
Sbjct: 804 CHAGFCGDSQP*AMSSLKKYIKTSKCRNA*ERHSGFPCQT 685
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|66792790|ref|NP_033881.2| beaded filament structural
protein 1, in lens-CP94 [Mus musculus]
         (663 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

11088                                                                  30   3.3  
>11088
          Length = 1298

 Score = 30.0 bits (66), Expect = 3.3,   Method: Compositional matrix adjust.
 Identities = 38/128 (29%), Positives = 55/128 (42%)
 Frame = -3

Query: 209 EVAALQNQLEEGREAVTHLQAQKAELQAQTTALEQAIKHAHECYDEELQLYNEQIENLRK 268
           EV  L++QL          Q + AE  AQ    E+ I+  +      LQL  E+ ENL +
Sbjct: 576 EVTGLKSQLRAA-------QIEHAEKMAQFAQEERHIREENLRLQRRLQLEMERRENLCR 418

Query: 269 EIEEAERSLERSSYDCRQLAVAQQTLRNELDRYHRIIEIEGSRLSSVFIETPISLITPSH 328
            + E+E SLE    D R          NE+ + H     EG  +    + +PI   + S 
Sbjct: 417 HLSESESSLEMD--DERHF--------NEMTKQH-----EGGMVRPRTVSSPIPYASASQ 283

Query: 329 GAPLSLGS 336
             P+S GS
Sbjct: 282 PRPMSPGS 259
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6755987|ref|NP_035837.1| vitronectin [Mus musculus]
         (478 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

33589                                                                  29   3.3  
02763                                                                  29   4.5  
>33589
          Length = 686

 Score = 29.3 bits (64), Expect = 3.3,   Method: Compositional matrix adjust.
 Identities = 13/31 (41%), Positives = 20/31 (64%)
 Frame = -1

Query: 184 ETAVRPGYPKLIQDVWGIEGPIDAAFTRINC 214
           ET V  G+ +L+Q V G+  P+DA  TR++ 
Sbjct: 659 ETPVLDGWYQLVQHVTGVLHPVDAHTTRVHL 567
>02763
          Length = 2590

 Score = 28.9 bits (63), Expect = 4.5,   Method: Compositional matrix adjust.
 Identities = 21/90 (23%), Positives = 43/90 (47%)
 Frame = +3

Query: 72  EDDYWSYDYVEEPKNNTNTGVQPENTSPPGDLNPRTDGTLKPTAFLDPEEQPSTPAPKVE 131
           E+ +W   +V+EPK NT    + + + P  DL+      ++   F + +++   P    +
Sbjct: 828 EERWWDGVFVDEPKINTR---KIDCSRPITDLDDEAQAKIEEMMFNERQKRMGLPQSHEQ 998

Query: 132 QQEEILRPDTTDQGTPEFPEEELCSGKPFD 161
           ++ ++LR     +G+P         G+PFD
Sbjct: 999 KKMDMLRQAWDAEGSP-------FRGQPFD 1067
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|9790159|ref|NP_062614.1| phosphatidylinositol
transfer protein, beta [Mus musculus]
         (271 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

14483                                                                  28   3.3  
04255                                                                  28   5.0  
07616                                                                  28   5.7  
>14483
          Length = 605

 Score = 28.5 bits (62), Expect = 3.3,   Method: Compositional matrix adjust.
 Identities = 16/45 (35%), Positives = 20/45 (44%), Gaps = 4/45 (8%)
 Frame = -3

Query: 175 PNWKKELANTPDCPRMCAYKLVTIKFKWWGLQSKV----ENFIQK 215
           P W   ++  P CPR  A +  T K  W  LQ  V     NF +K
Sbjct: 354 PRWPPRISADPGCPRSPASRAGTSKESWKRLQRSVVEQRTNFCRK 220
>04255
          Length = 1758

 Score = 27.7 bits (60), Expect = 5.0,   Method: Compositional matrix adjust.
 Identities = 16/68 (23%), Positives = 28/68 (41%)
 Frame = -3

Query: 135  TVEIVHIDIADRSQVEPADYKADEDPALFHSVKTKRGPLGPNWKKELANTPDCPRMCAYK 194
            T   + +  A     +PA       P  F   +++R    P  +++ + +P CPR C   
Sbjct: 1177 TRRTLQVTTAASKPRQPAPN--SWRPTAFWKRRSRRSKTSPTMRQQRSLSPVCPRSCRPT 1004

Query: 195  LVTIKFKW 202
                K+KW
Sbjct: 1003 SRRQKWKW 980
>07616
          Length = 1275

 Score = 27.7 bits (60), Expect = 5.7,   Method: Compositional matrix adjust.
 Identities = 10/21 (47%), Positives = 12/21 (57%)
 Frame = -3

Query: 176 NWKKELANTPDCPRMCAYKLV 196
           NW  +  NT  CPR+C Y  V
Sbjct: 448 NWISDSVNT*SCPRVCVYVCV 386
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|13384688|ref|NP_079596.1| hypothetical protein
LOC106264 [Mus musculus]
         (140 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

23768                                                                  27   3.4  
11468                                                                  27   3.5  
19142                                                                  26   4.5  
26742                                                                  25   7.3  
>23768
          Length = 1122

 Score = 26.6 bits (57), Expect = 3.4,   Method: Compositional matrix adjust.
 Identities = 12/34 (35%), Positives = 18/34 (52%)
 Frame = +1

Query: 92  RQSVTPDWTLPGRGHVPVPSVIYTDLSSHESSPG 125
           R S TP W+   RG +P P  I  + +  + +PG
Sbjct: 949 RYSFTPGWSGKIRGKIPFPKGIQNNRAYQDLNPG 1050
>11468
          Length = 851

 Score = 26.6 bits (57), Expect = 3.5,   Method: Compositional matrix adjust.
 Identities = 18/48 (37%), Positives = 25/48 (52%), Gaps = 2/48 (4%)
 Frame = -2

Query: 76  TPPWRPGPSR--AAEGSGRQSVTPDWTLPGRGHVPVPSVIYTDLSSHE 121
           TPPW    SR    +  G+ S+     + GR HV VPS+I   L S++
Sbjct: 190 TPPWPSSLSRR*TLKDGGKISLL---VMSGRSHVSVPSMISGSLHSNK 56
>19142
          Length = 991

 Score = 26.2 bits (56), Expect = 4.5,   Method: Compositional matrix adjust.
 Identities = 11/32 (34%), Positives = 14/32 (43%)
 Frame = -3

Query: 93  QSVTPDWTLPGRGHVPVPSVIYTDLSSHESSP 124
           + +  DWT  G   V V  +   D   HES P
Sbjct: 437 ELLIYDWTAGGETEVVVEDIERIDFEQHESDP 342
>26742
          Length = 459

 Score = 25.4 bits (54), Expect = 7.3,   Method: Compositional matrix adjust.
 Identities = 11/33 (33%), Positives = 17/33 (51%)
 Frame = +1

Query: 92  RQSVTPDWTLPGRGHVPVPSVIYTDLSSHESSP 124
           R   TP+W+   RG +P PS+   D +    +P
Sbjct: 352 RYPFTPEWSGKNRGIIPFPSIYENDQARQGLNP 450
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|58037205|ref|NP_081680.1| BCL2-associated athanogene
5 [Mus musculus]
         (447 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

16242                                                                  29   3.4  
20771                                                                  28   8.1  
03676                                                                  28   8.3  
>16242
          Length = 1513

 Score = 29.3 bits (64), Expect = 3.4,   Method: Compositional matrix adjust.
 Identities = 19/54 (35%), Positives = 27/54 (50%), Gaps = 4/54 (7%)
 Frame = +3

Query: 69  KRAAQETERLLKELEQNANHPHRIEIQNIFKEAQALVKDKI----VPFYSGGNC 118
           KR  Q+  R+L  LE+NAN+PH       F     +++ K+    V FYS   C
Sbjct: 720 KRKGQQELRILPGLEKNANNPH-----CCFSHRSEILQQKLTACNVEFYSMW*C 866
>20771
          Length = 674

 Score = 28.1 bits (61), Expect = 8.1,   Method: Compositional matrix adjust.
 Identities = 21/77 (27%), Positives = 34/77 (44%), Gaps = 11/77 (14%)
 Frame = +2

Query: 185 KINSVMCEVNKARGTLIALLMGVDSS-----------ETCRHLSCVLSGLIADLDALDVC 233
           K+ S    +    G ++A+   V SS           E  +H+ C +SGLIAD   L   
Sbjct: 173 KLGSTAIGIQTNEGVVLAVEKRVTSSLIEPTSIEKIMEVDKHIGCAMSGLIADSRTLIDR 352

Query: 234 GRTEIRNYRREVVEDIN 250
            R E +N+     E+++
Sbjct: 353 ARVEAQNHWFTYNENMS 403
>03676
          Length = 2457

 Score = 28.1 bits (61), Expect = 8.3,   Method: Compositional matrix adjust.
 Identities = 21/69 (30%), Positives = 33/69 (47%)
 Frame = -1

Query: 80   KELEQNANHPHRIEIQNIFKEAQALVKDKIVPFYSGGNCVTDEFEEGIQDIILRLTHVKT 139
            + L Q  N  H + IQN     ++ +K +I         +T E  EGI D  L L  ++T
Sbjct: 2103 QTLNQTTN-EHLLFIQNWINMGESFLKLEIRKRSGI*ATITTEGREGIGDRSLALFSIQT 1927

Query: 140  GGKVSLRKA 148
            GG   L+++
Sbjct: 1926 GGSEILKRS 1900
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|66792792|ref|NP_001019639.1| branched chain
aminotransferase 1, cytosolic isoform 1 [Mus musculus]
         (453 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

12752                                                                  29   3.4  
>12752
          Length = 466

 Score = 29.3 bits (64), Expect = 3.4,   Method: Compositional matrix adjust.
 Identities = 13/38 (34%), Positives = 19/38 (50%)
 Frame = +3

Query: 27  PNCSPGLSGSAVRHESPLCHVFPRSRSFVMACLPRATA 64
           P C+ G       H   LCH++   R+ V + LPR T+
Sbjct: 189 PACACGNQAETAEHYLLLCHLYTAIRNEVFSTLPRVTS 302
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6753532|ref|NP_034097.1| crystallin, gamma S [Mus
musculus]
         (178 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

03890                                                                  27   3.4  
>03890
          Length = 1219

 Score = 27.3 bits (59), Expect = 3.4,   Method: Compositional matrix adjust.
 Identities = 10/28 (35%), Positives = 18/28 (64%), Gaps = 1/28 (3%)
 Frame = +1

Query: 57   GHMYILPQGEYPEYQR-WMGLNDRLGSC 83
             HM++  Q ++P Y+R W+  +D+L  C
Sbjct: 1105 AHMWVFNQWQFPGYERKWIKKSDKLQHC 1188
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6754224|ref|NP_036112.1| homer homolog 1 isoform S
[Mus musculus]
         (186 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

05795                                                                  27   3.4  
>05795
          Length = 827

 Score = 27.3 bits (59), Expect = 3.4,   Method: Compositional matrix adjust.
 Identities = 12/33 (36%), Positives = 17/33 (51%), Gaps = 2/33 (6%)
 Frame = -1

Query: 154 PDVTQNSEPRAEPTQNAL--PFPHRYTFNSAIM 184
           PD+    +P+  P    L    PH YTF+S +M
Sbjct: 524 PDLRDTIKPKHRPICTVLLTKVPHEYTFHSKLM 426
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|110626109|ref|NP_031573.2| signal-regulatory protein
alpha [Mus musculus]
         (509 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

13135                                                                  29   3.5  
10921                                                                  29   4.5  
01526                                                                  28   6.7  
>13135
          Length = 849

 Score = 29.3 bits (64), Expect = 3.5,   Method: Compositional matrix adjust.
 Identities = 23/79 (29%), Positives = 33/79 (41%)
 Frame = -1

Query: 43  VSVAAGDSTVLNCTLTSLLPVGPIRWYRGVGPSRLLIYSFAGEYVPRIRNVSDTTKRNNM 102
           VS + G S VL C   S  P   ++W R            AGE +P       +  R ++
Sbjct: 351 VSKSEGQSLVLRCH-ASGRPTPSVKWTR-----------MAGELLP-------SGGREHL 229

Query: 103 DFSIRISNVTPADAGIYYC 121
           +  + I  + P  AGIY C
Sbjct: 228 ESDLVIPQLKPEHAGIYKC 172
>10921
          Length = 525

 Score = 28.9 bits (63), Expect = 4.5,   Method: Compositional matrix adjust.
 Identities = 35/155 (22%), Positives = 62/155 (40%), Gaps = 2/155 (1%)
 Frame = -2

Query: 183 LKWFKDGQELHPLETTVNPSGKNVSYNISSTVRVVLNSMDVNSKVICEVAHITLDRSPLR 242
           +KW   G +   L     P G+   Y IS T  +++ ++ +N +        +       
Sbjct: 512 VKWQLTGDDTF-LTLNDRPVGEGGHYIISGTYNLIIVNVTLNDQAEYTCKAGSESYFGFL 336

Query: 243 GIANLSNFIRVSPTVKVTQQSPTSMNQVNLTCRAERFYPEDLQLIWLENGNVSRNDTPKN 302
            + +L   + V       + +PT  +  NL+C A R +P    L W +NG V  + +  +
Sbjct: 335 TVIDLPQNLTVQ-----WETTPTPSSTSNLSCVASRAHPPP-PLSWFKNG-VRLDGSRAH 177

Query: 303 LTKNTD--GTYNYTSLFLVNSSAHREDVVFTCQVK 335
               TD  G  +  S   + +    E  VFTC+  
Sbjct: 176 YYATTDHSGYGDAVSTLPLETRGEDEGSVFTCEAS 72
>01526
          Length = 1862

 Score = 28.5 bits (62), Expect = 6.7,   Method: Compositional matrix adjust.
 Identities = 11/21 (52%), Positives = 13/21 (61%)
 Frame = -1

Query: 55   CTLTSLLPVGPIRWYRGVGPS 75
            C  T++L VG   WYRGVG  
Sbjct: 1832 CVCTTVLKVGMCVWYRGVGVC 1770
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|171906557|ref|NP_032838.2| peptidyl arginine
deiminase, type II [Mus musculus]
         (673 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

29037                                                                  30   3.5  
09034                                                                  30   3.9  
37054                                                                  29   5.4  
>29037
          Length = 1168

 Score = 30.0 bits (66), Expect = 3.5,   Method: Compositional matrix adjust.
 Identities = 14/59 (23%), Positives = 29/59 (49%), Gaps = 5/59 (8%)
 Frame = +3

Query: 554 RCLDWNRDILK-----RELALTEKDIIDLPALFKMDENHQARAFFPNMVNMIVLDKDLG 607
           RCLDW +D+ K      + +L++   I+   +F++      R    N++ + V + + G
Sbjct: 720 RCLDWFKDVQKSHGSVEKTSLSQVANINARGVFRLGRGMHTRLMLDNVIRLTVSEDEAG 896
>09034
          Length = 1125

 Score = 29.6 bits (65), Expect = 3.9,   Method: Compositional matrix adjust.
 Identities = 11/34 (32%), Positives = 24/34 (70%), Gaps = 1/34 (2%)
 Frame = -2

Query: 315 VSVFVCCMKDNYLFLKEVKNLVEKTNCELK-VCF 347
           +SV++CC+K N++++  V   +E++  +LK  C+
Sbjct: 737 ISVYLCCVKYNFVYM*TVIGNIERSESKLKCTCY 636
>37054
          Length = 402

 Score = 29.3 bits (64), Expect = 5.4,   Method: Compositional matrix adjust.
 Identities = 17/61 (27%), Positives = 32/61 (52%)
 Frame = -3

Query: 97  SSDKVTVNYYEEEGSAPIDQAGLFLTAIEISLDVDADRDGEVEKNNPKKASWTWGPEGQG 156
           ++D V   +Y+++ S+ +  AGL  T +   L V+ DR+ E  + N +  +    P G+ 
Sbjct: 382 TTDFVVPPHYKDQLSSLLLMAGLNATLVSADLQVEIDREREESERNLRSHTGRLLPTGKN 203

Query: 157 A 157
           A
Sbjct: 202 A 200
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|49257166|gb|AAH72598.1| Nbas protein [Mus musculus]
         (1866 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

14959                                                                  32   3.5  
>14959
          Length = 879

 Score = 31.6 bits (70), Expect = 3.5,   Method: Composition-based stats.
 Identities = 44/193 (22%), Positives = 78/193 (40%), Gaps = 8/193 (4%)
 Frame = +1

Query: 247 VQALEILLTYHGSHLLPHRLAILSNFPETTSPHEYAVLLPEACWNNDSLTIIPWAEHKHR 306
           +Q + ++     +H+L H+LA LSN       H++    P +   N+  T+  +  H   
Sbjct: 142 LQVIVMMKITSDNHILVHKLATLSN-----QAHKFPAKRPRSLTINNLATLAMFGNHAP- 303

Query: 307 AEDWCEELECRMVVEPSLQDDSEFLYAAQPELLQYRTPQLTVEKVMAWYQSRAEDIEHHA 366
                       +++P +Q +   L   +P LL +   QLT + +    Q+  + I H  
Sbjct: 304 ------------LLDPVIQVNFNNLTILKPALL-FNHVQLTSKHLAIVKQAMHKLINHFP 444

Query: 367 G----QVDCALSLVRLGVERHIPGLLTLCDDLVTLETLVYEA---GCDFTLTLKDL-QQM 418
                Q+D    L  L     +  L+ +   L T+   +Y      C   LT  DL  Q 
Sbjct: 445 DNSIHQMD*IT*LAELSNLVQLLNLIVIQTALFTIILHLYSTQMNSCPLNLTTPDLGTQR 624

Query: 419 KDFEKLRLLMEHC 431
           + F + RL++  C
Sbjct: 625 RRFNRYRLMVAIC 663
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|62751932|ref|NP_077222.3| coiled-coil domain
containing 132 [Mus musculus]
         (964 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

11876                                                                  30   3.6  
>11876
          Length = 838

 Score = 30.4 bits (67), Expect = 3.6,   Method: Composition-based stats.
 Identities = 17/49 (34%), Positives = 27/49 (55%), Gaps = 4/49 (8%)
 Frame = -2

Query: 612 LNVIRLVGKYM---QMMNILKPIAFDVIHFMSQLFDYYLYAIY-TFFGR 656
           LNV+ L    M   +  +++ P  +++IH + Q F  +LYA   TFF R
Sbjct: 600 LNVLHLFTDLMVIDECSSLMDPDMYNIIHILKQKFHLFLYAFL*TFFVR 454
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|76253922|ref|NP_001028931.1| transmembrane protein 2
[Mus musculus]
         (1383 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

05608                                                                  31   3.6  
>05608
          Length = 2687

 Score = 30.8 bits (68), Expect = 3.6,   Method: Compositional matrix adjust.
 Identities = 22/66 (33%), Positives = 30/66 (45%), Gaps = 2/66 (3%)
 Frame = +2

Query: 805  GKGLTFASDGSFPSDEGSSQEVT--ESLFVGESRNYGFQGGQNKYMGTGGIDQKPRTLPR 862
            G  + F+SDGSF S    SQEVT  +        + G QGG+       G     +  PR
Sbjct: 1091 GDSIPFSSDGSFASQRSDSQEVTGGQQFTAQRPPSGGRQGGRTMAANFSGS----QATPR 1258

Query: 863  NRTFPI 868
            + TF +
Sbjct: 1259 DNTFTV 1276
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|119392105|ref|NP_065602.2| arsenic (+3 oxidation
state) methyltransferase [Mus musculus]
         (376 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

10586                                                                  29   3.7  
>10586
          Length = 1036

 Score = 28.9 bits (63), Expect = 3.7,   Method: Compositional matrix adjust.
 Identities = 17/42 (40%), Positives = 25/42 (59%), Gaps = 1/42 (2%)
 Frame = +3

Query: 73  CRILDLGSGSGRDCYVLSQLVGEKGHV-TGIDMTEVQVEVAK 113
           C ILD+G GSG     L+    + GHV  G+D++   +EVA+
Sbjct: 276 CYILDIGCGSGLSGETLT----DNGHVWVGMDISPHMLEVAR 389
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|21362329|ref|NP_653116.1| nicotinamide nucleotide
adenylyltransferase 3 [Mus musculus]
         (245 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

08045                                                                  28   3.7  
26510                                                                  27   7.7  
>08045
          Length = 1408

 Score = 28.1 bits (61), Expect = 3.7,   Method: Compositional matrix adjust.
 Identities = 9/24 (37%), Positives = 15/24 (62%)
 Frame = +1

Query: 74  TSDWIRVDPWESEQAQWMETVKVL 97
           T+ W ++D W  EQ+ WM+   +L
Sbjct: 883 TATWSQIDQWSHEQSPWMQRAVIL 954
>26510
          Length = 1692

 Score = 26.9 bits (58), Expect = 7.7,   Method: Compositional matrix adjust.
 Identities = 22/73 (30%), Positives = 32/73 (43%), Gaps = 1/73 (1%)
 Frame = +3

Query: 56  KDLVA-SHHRVAMARLALQTSDWIRVDPWESEQAQWMETVKVLRHHHRELLRSSAQMDGP 114
           KDL+A S ++        Q  D+ +     + QA+  E     R  HR L R  A++  P
Sbjct: 249 KDLIAVSDYQTGRQYTYSQVKDYAKASGQRATQARLQE-----RGRHRHLHRQPARVLHP 413

Query: 115 DPSKTPSASAALP 127
           DP +  S    LP
Sbjct: 414 DPRRRLSRRDCLP 452
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|118601068|ref|NP_032869.2| prolactin induced protein
[Mus musculus]
         (146 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

02230                                                                  27   3.8  
04105                                                                  26   7.5  
>02230
          Length = 1733

 Score = 26.6 bits (57), Expect = 3.8,   Method: Compositional matrix adjust.
 Identities = 10/22 (45%), Positives = 15/22 (68%)
 Frame = +2

Query: 14  FLVLCLQLGIIESQDDENVRKP 35
             VLC  +GI + +DD N+R+P
Sbjct: 278 IFVLCTGMGIQQKKDD*NLRRP 343
>04105
          Length = 984

 Score = 25.8 bits (55), Expect = 7.5,   Method: Compositional matrix adjust.
 Identities = 7/25 (28%), Positives = 13/25 (52%)
 Frame = -3

Query: 82  FNYVQTRCLCNDHPIRFFWDIIITR 106
           F Y++ R +C   P ++ W   + R
Sbjct: 439 FQYIRRRIMCTPAPTQYLWSTTVNR 365
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|82884395|ref|XP_622099.2| PREDICTED: golgi
autoantigen, golgin subfamily a, 2 isoform 1 [Mus musculus]
         (987 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

25491                                                                  30   3.8  
>25491
          Length = 441

 Score = 30.4 bits (67), Expect = 3.8,   Method: Compositional matrix adjust.
 Identities = 23/79 (29%), Positives = 38/79 (48%), Gaps = 3/79 (3%)
 Frame = -2

Query: 359 ERAQLETHVSQLMESLKQLQVERDQYAE---NLKGESAMWQQRVQQMAEQVHTLKEEKEH 415
           E+  L  HV+ L  SL+  Q E+D   E   NL   SA  Q    ++ E++ +LK++   
Sbjct: 431 EKQSLTKHVTDLTASLQSAQSEKDSLTEQVTNLTASSAALQSERDKLCEEIASLKDBLXT 252

Query: 416 RERQVQELETSLAALRSQM 434
           + R ++     L A+R  +
Sbjct: 251 QTRNLEAQTDQLEAVRGDL 195
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|109809735|ref|NP_001034242.2| tectonic 1 [Mus
musculus]
         (593 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

06004                                                                  30   3.9  
09391                                                                  29   5.4  
>06004
          Length = 1574

 Score = 29.6 bits (65), Expect = 3.9,   Method: Compositional matrix adjust.
 Identities = 18/58 (31%), Positives = 28/58 (48%)
 Frame = +2

Query: 418 FTILRSTSQQDCLASEGLRTPVLFGYNVQSGCQLRLTGTIPCGLLAQKVQDLLRGQAF 475
           F + + T  Q+C+++E +RTPV      Q  C++  T       L + V    R QAF
Sbjct: 389 FCVKKRTPPQNCVSAEKMRTPVKTHALTQLKCRVSST-------LQESVHSATRVQAF 541
>09391
          Length = 1207

 Score = 28.9 bits (63), Expect = 5.4,   Method: Compositional matrix adjust.
 Identities = 15/39 (38%), Positives = 20/39 (51%)
 Frame = -2

Query: 433 EGLRTPVLFGYNVQSGCQLRLTGTIPCGLLAQKVQDLLR 471
           E +   V+  Y V  G  LRL  T+PCGL   +   LL+
Sbjct: 606 EEMHRVVMLDYLVFIGFMLRLQVTVPCGLQETRXYSLLK 490
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|40254624|ref|NP_032801.2| platelet-activating factor
acetylhydrolase, isoform 1b, alpha2 subunit [Mus musculus]
         (229 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

00248                                                                  28   3.9  
>00248
          Length = 1586

 Score = 27.7 bits (60), Expect = 3.9,   Method: Compositional matrix adjust.
 Identities = 15/44 (34%), Positives = 20/44 (45%), Gaps = 3/44 (6%)
 Frame = -3

Query: 88  GELENIKPKVIVVWVGTNNHENTAEEVA---GGIEAIVQLINTR 128
           G   N  PK +V W  TN HEN+ +E +         +   NTR
Sbjct: 258 GAKRN*PPKQMVYWYVTNGHENSFDESSIS*NSFSHRLSFFNTR 127
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|133778926|ref|NP_034265.2| enabled homolog isoform 1
[Mus musculus]
         (804 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

24228                                                                  30   4.0  
>24228
          Length = 395

 Score = 30.0 bits (66), Expect = 4.0,   Method: Composition-based stats.
 Identities = 13/25 (52%), Positives = 15/25 (60%)
 Frame = +1

Query: 32 FSRVHIYHHTGNNTFRVVGRKIQDH 56
          FS  HI  HTGN T+ +   KIQ H
Sbjct: 4  FSYTHIQKHTGNTTYTLNHSKIQTH 78
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|161016820|ref|NP_058574.3| aspartyl aminopeptidase
isoform b [Mus musculus]
         (473 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

31048                                                                  29   4.1  
01833                                                                  29   4.4  
07487                                                                  29   4.5  
34725                                                                  28   6.1  
>31048
          Length = 379

 Score = 28.9 bits (63), Expect = 4.1,   Method: Composition-based stats.
 Identities = 19/60 (31%), Positives = 27/60 (45%)
 Frame = -2

Query: 257 FAPRLDNLHSCFCALQALIDSCASPASLARDPHVRMVTLYDNEEVGSESAQGAQSLLTEL 316
           F  +L +LH     +    D     A  + D H +  TL +NE+   E+ Q  QS LT L
Sbjct: 213 FVEKLSSLH--IQMMHTCSDLLKDMARYSEDQHKKHKTLKENEQPTLEAVQNVQSTLTAL 40
>01833
          Length = 2427

 Score = 28.9 bits (63), Expect = 4.4,   Method: Compositional matrix adjust.
 Identities = 16/37 (43%), Positives = 20/37 (54%)
 Frame = +2

Query: 72   IAFAVGGQYVPGNGFSLIGAHTDSPCLRVKRKSRRSQ 108
            +AF VGG  +          HT  PC+R K+KSR SQ
Sbjct: 2279 LAFYVGGALIMFGSLFHFMLHT--PCIRQKKKSRGSQ 2383
>07487
          Length = 1268

 Score = 28.9 bits (63), Expect = 4.5,   Method: Compositional matrix adjust.
 Identities = 19/58 (32%), Positives = 26/58 (44%), Gaps = 9/58 (15%)
 Frame = +3

Query: 199 KGTPEPGPLGATDERH------HSVLMSLLCTHLGLSP---DSIMEMELCLADTQPAV 247
           KGT +P P G T  +H      +S    L CTH    P    S  E+E C+ + +  V
Sbjct: 549 KGTSQPCP*GVTHTQHYT*VRVYSYTHMLACTHTNTHPASHTSKCELEPCINNNKKHV 722
>34725
          Length = 692

 Score = 28.5 bits (62), Expect = 6.1,   Method: Compositional matrix adjust.
 Identities = 14/37 (37%), Positives = 17/37 (45%)
 Frame = -2

Query: 167 IHLQRNINENFGPNTEIHLVPILATAVQEELEKGTPE 203
           +HL    N   GP T +H VP+   AV     K  PE
Sbjct: 292 VHLAPTSNVQLGPKTNVHHVPMSKNAVLAPTSKTPPE 182
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|162287063|ref|NP_291048.2| cyclin M4 [Mus musculus]
         (771 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

16541                                                                  30   4.1  
>16541
          Length = 529

 Score = 30.0 bits (66), Expect = 4.1,   Method: Composition-based stats.
 Identities = 11/21 (52%), Positives = 14/21 (66%), Gaps = 2/21 (9%)
 Frame = -1

Query: 587 FNEHNRYCVRH--YLYTRNKP 605
            N H R+C+RH  YL+T N P
Sbjct: 97  LNTHTRHCIRHILYLFTHNAP 35
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|51573971|gb|AAU07932.1| lacrein [Mus musculus]
         (94 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

33693                                                                  26   4.2  
>33693
          Length = 627

 Score = 25.8 bits (55), Expect = 4.2,   Method: Compositional matrix adjust.
 Identities = 16/42 (38%), Positives = 24/42 (57%), Gaps = 2/42 (4%)
 Frame = +3

Query: 22  ADPNDEDDVVASEALNSVWS--GFSSEVMRIPDFAANTRLLI 61
           A PN   +++ + A   +WS  G  SE+M +P   A +RLLI
Sbjct: 144 AVPNSSANILFTRA---IWSFGGMMSEIMLVPFPLAASRLLI 260
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|225690614|ref|NP_579926.2| acyl-CoA thioesterase 7
isoform 2 [Mus musculus]
         (379 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

06176                                                                  28   4.3  
>06176
          Length = 577

 Score = 28.5 bits (62), Expect = 4.3,   Method: Compositional matrix adjust.
 Identities = 20/66 (30%), Positives = 28/66 (42%)
 Frame = -3

Query: 78  MIEEAGAIISTRHCNSQNGERCVAALARVERTDFLSPMCIGEVAHVSAEITYTSKHSVEV 137
           ++  AG     RH  S N           ER D LSP  IG V H      YT     E+
Sbjct: 170 ILVHAGVCFCGRHSPSCN-----------ERQDLLSPCMIGCVRHRLDLSLYTYPKE*EL 24

Query: 138 QVHVMS 143
           ++H+++
Sbjct: 23  RLHILT 6
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6755522|ref|NP_036159.1| evolutionarily conserved
signaling intermediate in Toll pathway [Mus musculus]
         (435 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

07918                                                                  29   4.3  
>07918
          Length = 1188

 Score = 28.9 bits (63), Expect = 4.3,   Method: Compositional matrix adjust.
 Identities = 18/61 (29%), Positives = 23/61 (37%)
 Frame = -2

Query: 35   LQALRGLHCSAATHKDEPWLVPRPPEPQRKPIKVPAMHEDSFKPSGNRERDKASFLNAVR 94
            L A+R   C  A H D+ W V RP E       + A H     P   + R +       R
Sbjct: 1052 LWAVRDWRCGRADHPDQHWTVGRPSE-------LCADHPSGLHPHRGKHRQRERLCGKER 894

Query: 95   S 95
            S
Sbjct: 893  S 891
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31981217|ref|NP_068682.2| silver [Mus musculus]
         (626 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

30755                                                                  29   4.4  
>30755
          Length = 1137

 Score = 29.3 bits (64), Expect = 4.4,   Method: Compositional matrix adjust.
 Identities = 22/65 (33%), Positives = 29/65 (44%)
 Frame = -1

Query: 473 GDAFELTVSCQGGLPKEACMDISSPGCQPPAQRLCQSVPPSPDCQLVLHQVLKGGSGTYC 532
           G  F  T S Q  L K  C  IS     PP +R   S+   PD +L    V+  G+ T  
Sbjct: 555 GVIFFCTRSVQLILAKNGCACISLTSSCPPPKRFLGSLANRPDNRLFASSVILRGNFTSS 376

Query: 533 LNVSL 537
            N+S+
Sbjct: 375 TNISV 361
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|32567788|ref|NP_666306.2|
phosphatidylinositol-binding clathrin assembly protein [Mus musculus]
         (660 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

09938                                                                  30   4.4  
02298                                                                  29   7.6  
>09938
          Length = 464

 Score = 29.6 bits (65), Expect = 4.4,   Method: Composition-based stats.
 Identities = 20/66 (30%), Positives = 31/66 (46%)
 Frame = -1

Query: 67  TTNSSWVVVFKSLITTHHLMVYGNERFIQYLASRNTLFNLSNFLDKSGLQGYDMSTFIRR 126
           T  + W++  KS   THH +V+    +I Y+      F + NF  K GL+      F   
Sbjct: 218 TLRAKWLISRKS--KTHHHLVFECCIYIIYMYVHMHTFRIBNFCLKKGLK------FFTG 63

Query: 127 YSRYLN 132
           Y R+L+
Sbjct: 62  YIRFLS 45
>02298
          Length = 1038

 Score = 28.9 bits (63), Expect = 7.6,   Method: Compositional matrix adjust.
 Identities = 13/32 (40%), Positives = 23/32 (71%)
 Frame = +1

Query: 89  GNERFIQYLASRNTLFNLSNFLDKSGLQGYDM 120
           G++  I +L S+  +  LS++L+ SG+QGYD+
Sbjct: 46  GSKAMIVFLGSKAMI--LSHYLNFSGIQGYDL 135
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6754524|ref|NP_034829.1| L-lactate dehydrogenase A
isoform 1 [Mus musculus]
         (332 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

04499                                                                  28   4.4  
23257                                                                  28   5.0  
>04499
          Length = 2081

 Score = 28.5 bits (62), Expect = 4.4,   Method: Compositional matrix adjust.
 Identities = 12/38 (31%), Positives = 22/38 (57%)
 Frame = +3

Query: 164 NLDSARFRYLMGERLGVHALSCHGWVLGEHGDSSVPVW 201
           + +S  ++++ G+ LG+HA+   GW L     + VP W
Sbjct: 141 SYESGVYKHVTGDYLGMHAVKMMGWGL----QAGVPYW 242
>23257
          Length = 1984

 Score = 28.1 bits (61), Expect = 5.0,   Method: Compositional matrix adjust.
 Identities = 12/40 (30%), Positives = 23/40 (57%)
 Frame = +2

Query: 45   ADELALVDVMEDKLKGEMMDLQHGSLFLKTPKIVSSKDYC 84
            AD++ +  ++ +KLK + + L H    +K+  +V S  YC
Sbjct: 1109 ADQILIPQIIPNKLKAKTLSL*HFFFTMKSQSLVHSCFYC 1228
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|124517716|ref|NP_033220.2| solute carrier family 12,
member 2 [Mus musculus]
         (1206 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

03892                                                                  30   4.5  
08272                                                                  30   4.7  
>03892
          Length = 1043

 Score = 30.4 bits (67), Expect = 4.5,   Method: Composition-based stats.
 Identities = 13/40 (32%), Positives = 19/40 (47%)
 Frame = -1

Query: 665 LNVIAPIISNFFLASYALINFSVFHASLAKSPGWRPAFKY 704
           LN++ P +S   L+ +    F  F  S   SP W P+  Y
Sbjct: 893 LNILKPSLSPALLSFFVSCTFLSFFVSRTFSPSWTPSLSY 774
>08272
          Length = 1326

 Score = 30.4 bits (67), Expect = 4.7,   Method: Composition-based stats.
 Identities = 11/23 (47%), Positives = 16/23 (69%)
 Frame = -2

Query: 191  QQYYYDTHTNTYYLRTFGHNTMD 213
            Q+  +DTHT+TY  +T GH + D
Sbjct: 1292 QKTIFDTHTHTYIFKTKGHKSND 1224
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|21729751|ref|NP_056560.1| retinol binding protein 3,
interstitial [Mus musculus]
         (1234 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

01489                                                                  30   4.5  
>01489
          Length = 796

 Score = 30.4 bits (67), Expect = 4.5,   Method: Composition-based stats.
 Identities = 12/29 (41%), Positives = 15/29 (51%)
 Frame = -1

Query: 1051 CELLTQVSELLVEHIWKKIVHTDALIIDM 1079
            C   TQ     + H+W KI HT  +I DM
Sbjct: 106  CSFFTQHFHFNIVHLWSKITHTYIIIYDM 20
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31542057|ref|NP_848851.2| ELMO domain containing 2
[Mus musculus]
         (293 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

00994                                                                  28   4.5  
07236                                                                  28   5.0  
>00994
          Length = 1431

 Score = 28.1 bits (61), Expect = 4.5,   Method: Compositional matrix adjust.
 Identities = 15/42 (35%), Positives = 25/42 (59%), Gaps = 3/42 (7%)
 Frame = +3

Query: 189 HQILSRSNHPKLGYSYAIVGINL---TEMAYSLLKSGALKLH 227
           H +L+ ++HP LGY   I+ I+L   T     LL++ ++ LH
Sbjct: 714 HMLLTLTDHPSLGYKLPILFISLY*FTFQDTCLLETNSILLH 839
>07236
          Length = 986

 Score = 27.7 bits (60), Expect = 5.0,   Method: Compositional matrix adjust.
 Identities = 15/35 (42%), Positives = 20/35 (57%), Gaps = 3/35 (8%)
 Frame = -2

Query: 5   LWEFFYGHFFRFWMKW---LLRQMTGKCELQRIFD 36
           L++F   H F F  KW   LLR + G C LQ +F+
Sbjct: 418 LFDFLQKHLFTFSSKWVQ*LLRLVQGTCFLQPLFN 314
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|38044104|ref|NP_081544.1| secernin 1 [Mus musculus]
         (414 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

31745                                                                  29   4.5  
>31745
          Length = 483

 Score = 28.9 bits (63), Expect = 4.5,   Method: Compositional matrix adjust.
 Identities = 14/35 (40%), Positives = 21/35 (60%)
 Frame = -3

Query: 271 SFLTTASIVSVLPQNRSSPCIHYFTGTPDPSRSIF 305
           +FL T  I+ V+P  +S  C H F+  P+P+  IF
Sbjct: 343 NFLNTK*ILRVIPLQKS--CNHVFSPNPNPASEIF 245
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|83716017|ref|NP_001028621.1| amyotrophic lateral
sclerosis 2 (juvenile) chromosome region, candidate 4 isoform 1 [Mus
musculus]
         (413 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

16091                                                                  29   4.5  
31680                                                                  28   5.5  
>16091
          Length = 1250

 Score = 28.9 bits (63), Expect = 4.5,   Method: Compositional matrix adjust.
 Identities = 8/32 (25%), Positives = 20/32 (62%)
 Frame = +2

Query: 341 IHLYEPSVNGSLWAAEAEEPILVPWIIVNLVV 372
           +++YE  + G +   +A +P+L  W+ + L++
Sbjct: 674 VYMYEKCLTGQICCPQARQPLLALWVFMFLIL 769
>31680
          Length = 388

 Score = 28.5 bits (62), Expect = 5.5,   Method: Compositional matrix adjust.
 Identities = 24/78 (30%), Positives = 29/78 (37%), Gaps = 3/78 (3%)
 Frame = +2

Query: 109 RPSSP---SLLRNENGIDAEPREEAVIPKPRRKAKKTQPAEPQYASELGVEDEDILTDEQ 165
           RP SP   S  R   GI   P      PKP    K    AEP Y +E   + E + T  +
Sbjct: 95  RPVSPAASSQSRLPRGIRPRPSYHKPEPKPVYHPKPVYKAEPVYKAEPVYKPEPVYTSPK 274

Query: 166 STLEHHSRFTAPTGVSQP 183
                   +T P  V  P
Sbjct: 275 PIYHPQPLYTTPKPVYHP 328
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31541939|ref|NP_080798.2| chitinase domain containing
1 isoform 2 [Mus musculus]
         (310 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

35489                                                                  28   4.6  
14026                                                                  27   10.0 
>35489
          Length = 972

 Score = 28.1 bits (61), Expect = 4.6,   Method: Compositional matrix adjust.
 Identities = 24/85 (28%), Positives = 34/85 (40%), Gaps = 8/85 (9%)
 Frame = -3

Query: 231 PPAVTPGYVQTLKDHRPRVVWDSQAAEHFFEYKKNRG--------GRHVVFYPTLKSLQV 282
           P +   G+V TLKD+   +  D    E FF +    G        G  V +    KS ++
Sbjct: 505 PASRCQGFVATLKDNYGFIENDKHDQEVFFHFSAFEGNASADLDLGDEVEYTLARKSSKM 326

Query: 283 RLELARELGVGVSIWELGQGLDYFY 307
             E  R+L  G     +G G D  Y
Sbjct: 325 SAENIRKLAKGT----IGPGEDIMY 263
>14026
          Length = 1003

 Score = 26.9 bits (58), Expect = 10.0,   Method: Compositional matrix adjust.
 Identities = 13/44 (29%), Positives = 17/44 (38%)
 Frame = +1

Query: 115 QLKRRGREMFEITGLHDVDQGWMRAVKKHAKGVRIVPRLLFEDW 158
           +    GR+MF   G+H   QG     K     +  V  L F  W
Sbjct: 676 RFNATGRQMFSADGIHLSQQGLYHLYKSLRGAILAVTTLTFNSW 807
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31542070|ref|NP_067305.2| acid phosphatase 1, soluble
isoform 2 [Mus musculus]
         (158 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

10228                                                                  27   4.8  
35006                                                                  25   9.6  
>10228
          Length = 986

 Score = 26.6 bits (57), Expect = 4.8,   Method: Compositional matrix adjust.
 Identities = 10/28 (35%), Positives = 19/28 (67%)
 Frame = -3

Query: 69  IHMQHIARQITKEDFATFDYILCMDESN 96
           +H++    QIT  D+++  +I C+D+SN
Sbjct: 591 LHIR*FLSQITIFDYSSLIFICCLDKSN 508
>35006
          Length = 290

 Score = 25.4 bits (54), Expect = 9.6,   Method: Compositional matrix adjust.
 Identities = 14/39 (35%), Positives = 18/39 (46%)
 Frame = -3

Query: 115 ELLGSYDPQKQLIIEDPYYGNDSDFEVVYQQCLRCCKAF 153
           +LL  YDP   L     ++ ND  FE      L+CC  F
Sbjct: 132 DLLCFYDPFHYLEKNYLFFTNDERFENHISSLLKCCSWF 16
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31543880|ref|NP_033423.2| tumor necrosis factor,
alpha-induced protein 3 [Mus musculus]
         (775 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

03787                                                                  30   4.8  
20065                                                                  29   8.9  
>03787
          Length = 2034

 Score = 29.6 bits (65), Expect = 4.8,   Method: Compositional matrix adjust.
 Identities = 11/34 (32%), Positives = 20/34 (58%)
 Frame = -3

Query: 99   GDGNCLMHAACQYMWGVQDTDLVLRKALCSTLKE 132
            GDGNC   A  + ++G +D     R+A+C  +++
Sbjct: 1045 GDGNCFFRALSKDVYGSEDFHAECRQAVCDLVEQ 944
>20065
          Length = 361

 Score = 28.9 bits (63), Expect = 8.9,   Method: Compositional matrix adjust.
 Identities = 15/32 (46%), Positives = 18/32 (56%)
 Frame = +1

Query: 349 VQHEYKKWQENSDQARRAAHAQNPLEPSTPQL 380
           V+H Y +W E       A HA  PLEPST Q+
Sbjct: 4   VEHYYNRWPE-------ARHASRPLEPSTNQM 78
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6679108|ref|NP_032748.1| nucleophosmin 1 [Mus
musculus]
         (292 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

07495                                                                  28   4.8  
>07495
          Length = 1838

 Score = 28.1 bits (61), Expect = 4.8,   Method: Compositional matrix adjust.
 Identities = 20/47 (42%), Positives = 26/47 (55%), Gaps = 1/47 (2%)
 Frame = -1

Query: 191  VKKSVRDTPAKNAQKSNQNGKDL-KPSTPRSKGQESFKKQEKTPKTP 236
            V  S  +T A  A K N + KD   P+TP   G++  KK  +TPKTP
Sbjct: 1424 VTSSDSETLAVTAAKINTDTKDAATPTTPAKTGRKGPKKVVRTPKTP 1284
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|110625631|ref|NP_001028490.2| component of oligomeric
golgi complex 7 [Mus musculus]
         (770 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

18198                                                                  30   4.9  
>18198
          Length = 421

 Score = 29.6 bits (65), Expect = 4.9,   Method: Compositional matrix adjust.
 Identities = 21/73 (28%), Positives = 33/73 (45%)
 Frame = +2

Query: 589 RIKQQLLLVSRMDSWNTAGIGETLTDDLPAFSLTPLEYISNIGQYIMSLPLNLEPFVTQE 648
           ++   L+  +   SW TA +  T  D  PAF  T L  +++I          L  ++  E
Sbjct: 41  QLSVTLVTAASTSSWCTAVLATTTCDTSPAFHNTTLISLTSI----------LSRYIVYE 190

Query: 649 DSALELALHAGKL 661
           +S L LAL   K+
Sbjct: 191 NSTLLLALSHKKM 229
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|21699066|ref|NP_660256.1| DIP13 alpha [Mus musculus]
         (707 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

05388                                                                  29   5.0  
38272                                                                  29   5.3  
>05388
          Length = 879

 Score = 29.3 bits (64), Expect = 5.0,   Method: Compositional matrix adjust.
 Identities = 15/39 (38%), Positives = 20/39 (51%)
 Frame = +3

Query: 528 LAARAIHNIFRMTESHLLVTCDCLKLIDPQTQVTRLTFP 566
           L  RA+H++ +    HL V C CLK   P T V  +  P
Sbjct: 405 LLVRAVHSLQQQQRHHLRVFCSCLK--SPWTAVHLIWMP 515
>38272
          Length = 749

 Score = 29.3 bits (64), Expect = 5.3,   Method: Compositional matrix adjust.
 Identities = 16/44 (36%), Positives = 24/44 (54%), Gaps = 3/44 (6%)
 Frame = +1

Query: 336 EDRRYCFQITSFDGKKSSI---LQAESKKDHEEWICTINNISKQ 376
           E  R  F++ S D  K ++    QA SKK ++EW+  +N I  Q
Sbjct: 520 EGGRVLFRLKSTDPNKPTVTVECQAGSKKSYDEWLGMLNMILDQ 651
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|22267448|ref|NP_083251.2| transmembrane protein 33
isoform 1 [Mus musculus]
         (247 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

21926                                                                  28   5.0  
22327                                                                  27   5.8  
14051                                                                  27   6.3  
12232                                                                  27   9.3  
>21926
          Length = 459

 Score = 27.7 bits (60), Expect = 5.0,   Method: Compositional matrix adjust.
 Identities = 13/44 (29%), Positives = 23/44 (52%), Gaps = 6/44 (13%)
 Frame = -2

Query: 205 RNLFNELRIVVEHIIMKPSCPLF------VRRLCLQSIAFISRL 242
           +NLF+   + V H+I +   P+F      +  LC+  + F+ RL
Sbjct: 212 QNLFSAASLHVHHVISQIESPIF*HTRERIDTLCIDHVQFVGRL 81
>22327
          Length = 323

 Score = 27.3 bits (59), Expect = 5.8,   Method: Compositional matrix adjust.
 Identities = 13/44 (29%), Positives = 23/44 (52%), Gaps = 6/44 (13%)
 Frame = -1

Query: 205 RNLFNELRIVVEHIIMKPSCPLF------VRRLCLQSIAFISRL 242
           +NLF+   + V H+I +   P+F      +  LC+  + F+ RL
Sbjct: 212 QNLFSAASLHVHHVISQIESPIF*HTKERIDTLCIDHVQFVGRL 81
>14051
          Length = 613

 Score = 27.3 bits (59), Expect = 6.3,   Method: Compositional matrix adjust.
 Identities = 11/22 (50%), Positives = 17/22 (77%)
 Frame = +2

Query: 91  DSCHYLLYSLIFVNSYPVTMSI 112
           DSCH+L + ++F+  YPVT S+
Sbjct: 530 DSCHWLTFIILFI--YPVTFSV 589
>12232
          Length = 418

 Score = 26.6 bits (57), Expect = 9.3,   Method: Compositional matrix adjust.
 Identities = 20/48 (41%), Positives = 25/48 (52%)
 Frame = +2

Query: 58  ALLANALTSALRLHQRLPHFQLSRAFLAQALLEDSCHYLLYSLIFVNS 105
           AL  N+  SA R H  L HF LS    A A+  +  H++  S IF NS
Sbjct: 185 ALATNSSESAFRFHSYLYHFPLS---FASAVYVNP-HFVRASAIFRNS 316
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|27754054|ref|NP_080827.2| dephospho-CoA kinase domain
containing [Mus musculus]
         (231 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

24160                                                                  27   5.0  
16773                                                                  27   8.8  
>24160
          Length = 854

 Score = 27.3 bits (59), Expect = 5.0,   Method: Compositional matrix adjust.
 Identities = 14/39 (35%), Positives = 23/39 (58%), Gaps = 7/39 (17%)
 Frame = +1

Query: 9   GIASGKSSVIQV-------FQQLGCAVIDVDVIARHVVQ 40
            + SG+++V+ V       F QL  ++ID+DVI  H+ Q
Sbjct: 343 AVPSGQATVVLVN*TRLWKFTQLDASLIDIDVIXEHLRQ 459
>16773
          Length = 433

 Score = 26.6 bits (57), Expect = 8.8,   Method: Compositional matrix adjust.
 Identities = 15/39 (38%), Positives = 21/39 (53%)
 Frame = +3

Query: 61 NGDIDRKVLGDLIFNQPDRRQLLNSITHPEIRKEMMKET 99
          N  I +K L   I +   R+ L +SITH  IRK++   T
Sbjct: 3  NSIIIQKYLQCSIIHNSIRKDLQSSITHNRIRKDLHSST 119
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|13195630|ref|NP_077163.1| coiled-coil domain
containing 127 [Mus musculus]
         (260 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

09968                                                                  28   5.1  
>09968
          Length = 2913

 Score = 27.7 bits (60), Expect = 5.1,   Method: Compositional matrix adjust.
 Identities = 10/23 (43%), Positives = 14/23 (60%)
 Frame = -1

Query: 8   PNWNIRPNARADGGDGSKWNYAL 30
           P  N  P+ R +  DG KWN+A+
Sbjct: 825 PGKNTEPSERDNACDGGKWNFAM 757
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|161016786|ref|NP_084017.2| protein tyrosine
phosphatase, receptor type, f polypeptide (PTPRF), interacting protein
(liprin), alpha 3 [Mus musculus]
         (1194 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

31117                                                                  30   5.1  
>31117
          Length = 856

 Score = 30.0 bits (66), Expect = 5.1,   Method: Composition-based stats.
 Identities = 10/25 (40%), Positives = 16/25 (64%)
 Frame = +3

Query: 960 DWLPSLGLPQYRSYFMESLVDARML 984
           +W+  LG P Y+S F  +++D R L
Sbjct: 111 EWIEELGFPHYKSCFTTNMIDGRRL 185
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31560273|ref|NP_075617.2| paralemmin [Mus musculus]
         (383 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

28209                                                                  28   5.1  
>28209
          Length = 839

 Score = 28.5 bits (62), Expect = 5.1,   Method: Compositional matrix adjust.
 Identities = 33/107 (30%), Positives = 47/107 (43%), Gaps = 9/107 (8%)
 Frame = -1

Query: 172 EITVEKDKVTGE-----TRVLSSTTVLPRDPLPQG-VKVYEDETKVVHAVDGIAENGIQP 225
           EIT+ + K+ GE     T  L+S + LP +  P   VKVYEDE  ++   D I   G+  
Sbjct: 743 EITILR-KIRGEGEGVPTHCLTSISPLPGEQGPACLVKVYEDEEDILKVNDMIEVVGVLS 567

Query: 226 LSSSEVDELIHKADEVTLS---EAGSTAGPAEPRGLAEDVTRTTPSR 269
           +  S    L+   D+  L     A   A    P     D TR+  +R
Sbjct: 566 VDPS----LVQFGDQHPLGTTMSAAELAAHTPPPPWCRDSTRSWCAR 438
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|51479181|ref|NP_032810.2| immunoglobulin (CD79A)
binding protein 1 [Mus musculus]
         (340 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

20715                                                                  28   5.1  
33688                                                                  28   5.5  
>20715
          Length = 767

 Score = 28.1 bits (61), Expect = 5.1,   Method: Compositional matrix adjust.
 Identities = 15/32 (46%), Positives = 19/32 (59%)
 Frame = +3

Query: 196 LHLRRWIAVSLEELESIDQEIKILKEKDSPRE 227
           LH  R  AVSL+E +     +KIL  KD+P E
Sbjct: 369 LHCSREAAVSLKEADLAGVVLKILNNKDTPPE 464
>33688
          Length = 1321

 Score = 28.1 bits (61), Expect = 5.5,   Method: Compositional matrix adjust.
 Identities = 10/20 (50%), Positives = 14/20 (70%)
 Frame = -1

Query: 84  ALQGALTMKQVNPSKRLDHL 103
           A+ G  TM Q+NP  +LDH+
Sbjct: 100 AISGLSTMMQINPGMKLDHM 41
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6754382|ref|NP_034711.1| CD47 antigen [Mus musculus]
         (324 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

00145                                                                  28   5.1  
>00145
          Length = 2325

 Score = 28.1 bits (61), Expect = 5.1,   Method: Compositional matrix adjust.
 Identities = 18/58 (31%), Positives = 29/58 (50%), Gaps = 8/58 (13%)
 Frame = +3

Query: 229  LGLIVISTGILI----LLQYNVFMTAFGMTSFTIAILIT----QVLGYVLALVGLCLC 278
            LG +++   IL     L+   VF    G+ SF + +       + LG++L  +GLCLC
Sbjct: 1557 LGRVLVRLAILFPSVRLISLLVFRHVTGLFSFFVGLXFLCSFPRFLGFLLVFIGLCLC 1730
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|213512915|ref|NP_061376.2| basic FGF repressed, zinc
binding protein [Mus musculus]
         (295 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

13835                                                                  28   5.2  
15569                                                                  27   9.2  
>13835
          Length = 1452

 Score = 27.7 bits (60), Expect = 5.2,   Method: Compositional matrix adjust.
 Identities = 10/24 (41%), Positives = 17/24 (70%)
 Frame = -1

Query: 139 FNSWFLITLLHVWMCLVRMKQEGR 162
           F+S+FL+ LLH W C  ++ ++ R
Sbjct: 843 FSSFFLLALLHDWHCPCQVPEDSR 772
>15569
          Length = 894

 Score = 26.9 bits (58), Expect = 9.2,   Method: Compositional matrix adjust.
 Identities = 9/19 (47%), Positives = 14/19 (73%)
 Frame = -3

Query: 143 FLITLLHVWMCLVRMKQEG 161
           FL++L H+W+ L +  QEG
Sbjct: 583 FLVSLFHIWVVLRKWSQEG 527
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|7106277|ref|NP_034105.1| casein kinase 2, beta
polypeptide [Mus musculus]
         (215 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

38764                                                                  27   5.2  
>38764
          Length = 1159

 Score = 27.3 bits (59), Expect = 5.2,   Method: Compositional matrix adjust.
 Identities = 14/34 (41%), Positives = 19/34 (55%), Gaps = 3/34 (8%)
 Frame = +1

Query: 132 MVKLYCPKCMDVYTPKSSRHHH---TDGAYFGTG 162
            +K   PK +  + P S+RHHH   TDG +F  G
Sbjct: 538 WLKATPPKLLRQHGPLSARHHHV*ATDGIWFQAG 639
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|34303979|ref|NP_899131.1| paraoxonase 2 [Mus
musculus]
         (354 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

15900                                                                  28   5.4  
00726                                                                  28   6.6  
10586                                                                  28   6.8  
27844                                                                  28   7.3  
>15900
          Length = 734

 Score = 28.1 bits (61), Expect = 5.4,   Method: Compositional matrix adjust.
 Identities = 14/36 (38%), Positives = 23/36 (63%)
 Frame = -3

Query: 186 SDPFLKYLETYLNLHWANVVYYSPEEVKLVAEGFDS 221
           S+ F K L+ Y+N+H +NV+ +   E  L+  G+DS
Sbjct: 546 SNRFWKELQDYINIHCSNVINFKINEQVLIF-GYDS 442
>00726
          Length = 1388

 Score = 27.7 bits (60), Expect = 6.6,   Method: Compositional matrix adjust.
 Identities = 11/33 (33%), Positives = 16/33 (48%)
 Frame = +3

Query: 169  IIAVGPTHFYATNDHYFSDPFLKYLETYLNLHW 201
            ++   P  + A   HYFS PF+  L  +L   W
Sbjct: 1098 LLWCWPCMYLALRPHYFSSPFIAILLVFLE*SW 1196
>10586
          Length = 1036

 Score = 27.7 bits (60), Expect = 6.8,   Method: Compositional matrix adjust.
 Identities = 14/40 (35%), Positives = 24/40 (60%)
 Frame = +3

Query: 127 YLFVVNHPQFKSTVEIFKFQEEENSLLHLKTIKHELLPSV 166
           Y+F V    F S++EIF+F +EEN++      +H+  P +
Sbjct: 54  YIFQV----F*SSIEIFRFIDEENNMASRDRPEHQAPPEI 161
>27844
          Length = 395

 Score = 27.7 bits (60), Expect = 7.3,   Method: Compositional matrix adjust.
 Identities = 10/15 (66%), Positives = 13/15 (86%)
 Frame = +1

Query: 72 PGLHSFAPDKPGGIL 86
          PGLH+ AP++PGG L
Sbjct: 28 PGLHAHAPEQPGGCL 72
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|94401294|ref|XP_001000738.1| PREDICTED: similar to
phosphatidylinositol-specific phospholipase C, X domain containing 2
[Mus musculus]
         (328 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

08678                                                                  28   5.5  
36578                                                                  28   6.0  
27509                                                                  28   7.2  
32187                                                                  28   7.6  
23920                                                                  27   7.7  
>08678
          Length = 691

 Score = 28.1 bits (61), Expect = 5.5,   Method: Compositional matrix adjust.
 Identities = 11/27 (40%), Positives = 14/27 (51%)
 Frame = +3

Query: 116 IYFIHGLFGIKVWDGLMEIDAFLTQHP 142
           +YF+ GLF   VWD L  +   L   P
Sbjct: 528 VYFLRGLFKQSVWDNLQSLHKALANTP 608
>36578
          Length = 412

 Score = 27.7 bits (60), Expect = 6.0,   Method: Compositional matrix adjust.
 Identities = 13/32 (40%), Positives = 16/32 (50%), Gaps = 3/32 (9%)
 Frame = -3

Query: 152 HFYAMDESHH---KCLVLRIQEAFGNKLCPAC 180
           HFY + +SHH   KC   R +  F    CP C
Sbjct: 224 HFYYLSKSHHINNKCSCFRYKLTFTVIXCPCC 129
>27509
          Length = 640

 Score = 27.7 bits (60), Expect = 7.2,   Method: Compositional matrix adjust.
 Identities = 13/31 (41%), Positives = 14/31 (45%)
 Frame = +2

Query: 2   GTICSPNPSGTKTASEVCNADWMASLPAHLH 32
           GT CS  PS    +   C   W AS P  LH
Sbjct: 428 GTCCSGTPSPAPGSGAACTTFWSASCPPRLH 520
>32187
          Length = 1385

 Score = 27.7 bits (60), Expect = 7.6,   Method: Compositional matrix adjust.
 Identities = 13/24 (54%), Positives = 17/24 (70%)
 Frame = +1

Query: 44   SHDSFSYWVDEKSPVGPDQTQAVI 67
            SHD FS+WVD +S VG   T +V+
Sbjct: 1021 SHDFFSHWVDLRSEVG*LVTSSVV 1092
>23920
          Length = 757

 Score = 27.3 bits (59), Expect = 7.7,   Method: Compositional matrix adjust.
 Identities = 14/44 (31%), Positives = 21/44 (47%)
 Frame = +2

Query: 147 FLDFNHFYAMDESHHKCLVLRIQEAFGNKLCPACSVESMTLRSL 190
           F    H  +    HH  L   +++     +CPAC+ ES  LR+L
Sbjct: 596 FQKHTHTMSSPSKHHDPL-FPLRDPLPQSVCPACTWESSDLRAL 724
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|165972305|ref|NP_033321.2| syntaxin binding protein 1
isoform b [Mus musculus]
         (594 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

06130                                                                  29   5.7  
>06130
          Length = 1831

 Score = 28.9 bits (63), Expect = 5.7,   Method: Compositional matrix adjust.
 Identities = 14/25 (56%), Positives = 17/25 (68%)
 Frame = -3

Query: 226 ARSQLLILDRGFDPSSPVLHELTFQ 250
           + S LL +DRG D  SPVLH L+ Q
Sbjct: 125 SHSNLLGIDRGDDLPSPVLHSLSTQ 51
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|94405460|ref|XP_995733.1| PREDICTED: transmembrane
emp24 protein transport domain containing 7 [Mus musculus]
         (224 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

03590                                                                  27   5.7  
>03590
          Length = 1068

 Score = 27.3 bits (59), Expect = 5.7,   Method: Compositional matrix adjust.
 Identities = 17/51 (33%), Positives = 21/51 (41%), Gaps = 6/51 (11%)
 Frame = -1

Query: 107 SFASAMSFLLSHTKQ------CISISKLEKTHLCFPVRTESVPLPRWNPPA 151
           S +S   + L H +Q      C      +    C PVRT  VP  RW PP 
Sbjct: 951 SVSSTAQWGLDHNQQRRSVWACSHRRSWQTRQPCVPVRTLPVPCCRWRPPC 799
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|22748609|ref|NP_665839.1| regulator of G protein
signaling 9-binding protein [Mus musculus]
         (237 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

02395                                                                  27   5.8  
>02395
          Length = 2012

 Score = 27.3 bits (59), Expect = 5.8,   Method: Compositional matrix adjust.
 Identities = 11/23 (47%), Positives = 15/23 (65%)
 Frame = -1

Query: 10   LDALNKTTACYHHLVLTVGGSAD 32
            LD +NK TACYH L+L     ++
Sbjct: 1307 LDPINKQTACYHILLLAYNDVSN 1239
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|82796166|ref|XP_140801.6| PREDICTED: UPF2 regulator
of nonsense transcripts homolog isoform 1 [Mus musculus]
         (1269 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

31955                                                                  30   5.8  
>31955
          Length = 981

 Score = 30.0 bits (66), Expect = 5.8,   Method: Composition-based stats.
 Identities = 19/49 (38%), Positives = 25/49 (51%)
 Frame = -2

Query: 163 LDSSLKKNTAFVKKLKTITEQQRDSLSHDFNGLNLSKYIAEAVASIVEA 211
           L SSL  +T   + L +IT   R SLS   N  +LSK  A A + +  A
Sbjct: 344 LRSSLAVSTTGTRSLSSITSPARPSLSQTANNFSLSKSTALASSHVGSA 198
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6754450|ref|NP_034764.1| fatty acid binding protein
5, epidermal [Mus musculus]
         (135 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

33478                                                                  26   5.9  
30748                                                                  26   6.0  
34588                                                                  25   9.0  
>33478
          Length = 717

 Score = 25.8 bits (55), Expect = 5.9,   Method: Compositional matrix adjust.
 Identities = 11/40 (27%), Positives = 19/40 (47%), Gaps = 8/40 (20%)
 Frame = +1

Query: 92  GALVQHQQWDGKEST--------ITRKLKDGKMIVECVMN 123
             L++HQ W+ KE +             K+ KM ++C+ N
Sbjct: 109 SFLIEHQAWEFKEKS*LKLKATKFIVHFKNVKMYIQCIQN 228
>30748
          Length = 627

 Score = 25.8 bits (55), Expect = 6.0,   Method: Compositional matrix adjust.
 Identities = 11/35 (31%), Positives = 19/35 (54%)
 Frame = +2

Query: 85  TVCTFQDGALVQHQQWDGKESTITRKLKDGKMIVE 119
            VC   D AL+    WDG  ++  ++ +DG  +V+
Sbjct: 383 VVCA-NDAALMTWLSWDGSAASDAQRRRDGNCVVQ 484
>34588
          Length = 418

 Score = 25.0 bits (53), Expect = 9.0,   Method: Compositional matrix adjust.
 Identities = 11/44 (25%), Positives = 21/44 (47%)
 Frame = -1

Query: 81  RKTETVCTFQDGALVQHQQWDGKESTITRKLKDGKMIVECVMNN 124
           R T TVC+ +        +W G +S +   L   ++ V C++ +
Sbjct: 247 RGTRTVCSSRATKKATGNEWLGAKSALNLSLSGDRLRVPCMITH 116
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|82893762|ref|XP_918873.1| PREDICTED: similar to
CG3520-PA isoform 8 [Mus musculus]
         (1798 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

27227                                                                  30   6.0  
>27227
          Length = 379

 Score = 30.4 bits (67), Expect = 6.0,   Method: Composition-based stats.
 Identities = 18/60 (30%), Positives = 27/60 (45%)
 Frame = +2

Query: 1442 LLGLWVMPPLIHGLSLNIKKYLLVSMPLWAKHVSDEQIQGFVENLMVEVFKTASQPCHPE 1501
            L+G  V PP  HG        L      WA  V +E ++G + +  ++  +TA   C PE
Sbjct: 86   LVGHKVGPPY*HGRRCGFLAVLSAGDAAWALPVDEEDVRGALHHHQMQQTETAQSECCPE 265
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|7949154|ref|NP_058065.1| thiopurine
S-methyltransferase [Mus musculus]
         (240 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

21811                                                                  27   6.1  
08024                                                                  27   7.7  
31196                                                                  27   9.4  
>21811
          Length = 385

 Score = 27.3 bits (59), Expect = 6.1,   Method: Compositional matrix adjust.
 Identities = 22/80 (27%), Positives = 38/80 (47%), Gaps = 4/80 (5%)
 Frame = +3

Query: 4   DMKEHPDAEVQKNQVLTLEDWKEKWVTRHISFHQEQGHQLLKKHLDTF---LKG-QSGLR 59
           ++K H D  + +N +  LE+W ++W  R   F  ++ + L  +H  ++   L G  S  R
Sbjct: 84  EIKTHEDHHILQNDLKKLEEWADEWGMR---FKAKKCYVLSVRHKASYFYLLGGPHSAAR 254

Query: 60  VFFPLCGKAIEMKWFADRGH 79
               L G + + K   DR H
Sbjct: 255 *LQSLLGSSDQ*KSLMDRTH 314
>08024
          Length = 1248

 Score = 26.9 bits (58), Expect = 7.7,   Method: Compositional matrix adjust.
 Identities = 12/32 (37%), Positives = 19/32 (59%), Gaps = 1/32 (3%)
 Frame = +1

Query: 154 NPGDHDRYADIILSLLRKEFQYLV-AVLSYDP 184
           N GDH     ++ +L  KEF+++V  + S DP
Sbjct: 178 NMGDHSEAQKVVFALAMKEFEHVVKNMTSADP 273
>31196
          Length = 521

 Score = 26.6 bits (57), Expect = 9.4,   Method: Compositional matrix adjust.
 Identities = 11/25 (44%), Positives = 16/25 (64%)
 Frame = -3

Query: 131 FDLPRANIGKFDRIWDRGALVAINP 155
           FD+ +A    FDR+W RG L+ +N 
Sbjct: 438 FDISKA----FDRVWHRGLLLKLNS 376
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|94395634|ref|XP_619141.3| PREDICTED: hypothetical
protein LOC320557 [Mus musculus]
         (825 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

33826                                                                  29   6.1  
>33826
          Length = 385

 Score = 29.3 bits (64), Expect = 6.1,   Method: Composition-based stats.
 Identities = 15/38 (39%), Positives = 20/38 (52%)
 Frame = -2

Query: 165 VDLLDNCTHEELENSSEDYLSSLRCGDPEHPECFSSLN 202
           +D+L   TH    +  +DY S L C DP    C+S LN
Sbjct: 378 LDILVTPTHTADTDPHQDYSSDLDCIDPVKNFCYS*LN 265
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|15638942|ref|NP_034009.2| carnitine
deficiency-associated gene expressed in ventricle 1 [Mus musculus]
         (676 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

20789                                                                  29   6.2  
>20789
          Length = 666

 Score = 28.9 bits (63), Expect = 6.2,   Method: Compositional matrix adjust.
 Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 11/74 (14%)
 Frame = -2

Query: 135 ETVADTNKQYEELMEAFKTLHKECEQLK-----------TSGFSTAEIRRDISAMEEEKD 183
           E VAD   Q E+L    +TL  + E L+           +     AE      A+E+EK 
Sbjct: 320 EIVADLEAQTEKLTSQLETLKDQVESLEGVQRNLEGEKMSLEVKIAEQEEQKEALEKEKG 141

Query: 184 QLMKRVERLKKRVE 197
            L+K VER K+RVE
Sbjct: 140 DLLKDVERWKERVE 99
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|166235165|ref|NP_033331.2| synaptophysin [Mus
musculus]
         (314 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

27720                                                                  28   6.2  
>27720
          Length = 391

 Score = 27.7 bits (60), Expect = 6.2,   Method: Compositional matrix adjust.
 Identities = 15/43 (34%), Positives = 23/43 (53%)
 Frame = -2

Query: 169 KMATDPENIIKEMPMCRQTGNTCKELRDPVTSGLNTSVVFGFL 211
           +M  DP N   EM   +  G + K  +  V++GL T+ +FG L
Sbjct: 192 EMKNDPFNWSAEMDSAKDHGTSDKSPQAQVSTGLPTTNIFGGL 64
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|23956398|ref|NP_705822.1| protein-L-isoaspartate
(D-aspartate) O-methyltransferase domain containing 2 [Mus musculus]
         (359 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

26754                                                                  28   6.2  
>26754
          Length = 1206

 Score = 28.1 bits (61), Expect = 6.2,   Method: Compositional matrix adjust.
 Identities = 11/28 (39%), Positives = 15/28 (53%)
 Frame = -3

Query: 51  YKDLAWKHGNIHLSAPCIYSEVMEALDL 78
           +K   W H NI L APC++  V    D+
Sbjct: 796 WKS*QWNH*NISLGAPCVFLSVSRLTDV 713
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|58037395|ref|NP_083429.1| secretory carrier membrane
protein 1 [Mus musculus]
         (338 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

09259                                                                  28   6.2  
>09259
          Length = 1233

 Score = 27.7 bits (60), Expect = 6.2,   Method: Compositional matrix adjust.
 Identities = 17/39 (43%), Positives = 22/39 (56%), Gaps = 2/39 (5%)
 Frame = -3

Query: 225 YICQFAVHVLQAAGFHNWGNCG-W-ISSLTGLNKNIPVG 261
           Y CQFA+H +   G    G CG W +  +T LNK+I  G
Sbjct: 232 YCCQFALHNVDVLGHCLSGLCGLWSVDLVTALNKHITSG 116
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|125628650|ref|NP_080285.2| coiled-coil domain
containing 47 [Mus musculus]
         (483 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

11324                                                                  28   6.4  
>11324
          Length = 2647

 Score = 28.5 bits (62), Expect = 6.4,   Method: Compositional matrix adjust.
 Identities = 11/25 (44%), Positives = 15/25 (60%)
 Frame = +3

Query: 143 VTGLLAYIMNYIIGKNKNSRLAQAW 167
           V+ LL+Y+ NYI+G   N    Q W
Sbjct: 231 VSDLLSYLFNYILG*TTNGHFDQTW 305
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|62526126|ref|NP_780562.2| exocyst complex component 6
[Mus musculus]
         (804 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

11914                                                                  29   6.4  
>11914
          Length = 978

 Score = 29.3 bits (64), Expect = 6.4,   Method: Composition-based stats.
 Identities = 13/48 (27%), Positives = 25/48 (52%), Gaps = 1/48 (2%)
 Frame = -2

Query: 651 PGKVAQTACMSACQHLSTSLMQMLLDSELKQ-ISMGAVQQFNLDVIQC 697
           PG+   T C   CQ++ +  + ++L++ L+  +S  A      DV+ C
Sbjct: 146 PGRYTFTLCTCTCQNMPSEQLNLILNNSLRMLLSFWASLSIKSDVLVC 3
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|66955862|ref|NP_083713.1| cytoskeleton associated
protein 5 [Mus musculus]
         (2011 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

03392                                                                  31   6.4  
12234                                                                  30   7.2  
>03392
          Length = 1440

 Score = 30.8 bits (68), Expect = 6.4,   Method: Composition-based stats.
 Identities = 11/40 (27%), Positives = 25/40 (62%)
 Frame = +1

Query: 120 EKGESVQEELLKGLDNKNPKIIVACIETLRKALSEFGSKI 159
           EKG  +   +++ + NK+PK++V   + L + + E+G+ +
Sbjct: 493 EKGNQISGMIIRTITNKSPKVMVPLFKALVRPIIEYGNPV 612
>12234
          Length = 739

 Score = 30.4 bits (67), Expect = 7.2,   Method: Compositional matrix adjust.
 Identities = 10/41 (24%), Positives = 26/41 (63%)
 Frame = +1

Query: 119 IEKGESVQEELLKGLDNKNPKIIVACIETLRKALSEFGSKI 159
           ++KG  +   +++ + NK+PK++V   + L + + E+G+ +
Sbjct: 337 VKKGNQISXMIIRTIXNKSPKVMVPLFKALVRPIIEYGNPL 459
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|21313516|ref|NP_079787.1| hypothetical protein
LOC66359 [Mus musculus]
         (117 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

04453                                                                  25   6.6  
04927                                                                  25   9.4  
>04453
          Length = 2133

 Score = 25.4 bits (54), Expect = 6.6,   Method: Composition-based stats.
 Identities = 12/34 (35%), Positives = 21/34 (61%)
 Frame = -3

Query: 20  ILDVENTPCARESILYGSLGSIVTGLGHFLVTSR 53
           I++V+ T  A  ++  GSL ++V  +GH L+  R
Sbjct: 787 IINVKITSSAEGNVRVGSLLTLVI*IGHVLINQR 686
>04927
          Length = 2678

 Score = 24.6 bits (52), Expect = 9.4,   Method: Composition-based stats.
 Identities = 10/30 (33%), Positives = 16/30 (53%)
 Frame = +2

Query: 75  HCRYNFAKQRIQERIAREGIKNKILYESTH 104
           HCR N+ +  I      + IKNKI++   +
Sbjct: 533 HCRANYIRFTINIHDFAQNIKNKIIFNKKY 622
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|23957686|ref|NP_705809.1| glycoprotein m6a [Mus
musculus]
         (278 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

26137                                                                  27   6.6  
06184                                                                  27   6.7  
>26137
          Length = 460

 Score = 27.3 bits (59), Expect = 6.6,   Method: Compositional matrix adjust.
 Identities = 13/32 (40%), Positives = 18/32 (56%)
 Frame = -3

Query: 26  PYASLIATILLYAGVALFCGCGHEALSGTVNI 57
           P A+L+  +    GV+ FCGCG    SGT  +
Sbjct: 206 PDAALVPGL*HGIGVSTFCGCGGVCKSGTTGV 111
>06184
          Length = 1420

 Score = 27.3 bits (59), Expect = 6.7,   Method: Compositional matrix adjust.
 Identities = 17/59 (28%), Positives = 25/59 (42%), Gaps = 10/59 (16%)
 Frame = +3

Query: 27  YASLIATILLYAGVALFCG----------CGHEALSGTVNILQTYFELARTAGDTLDVF 75
           Y ++  ++     V L CG          CGHEAL G V+   T F+ +    DT +  
Sbjct: 528 YGAVTFSLAFLGQVILVCGFMDQYITVLPCGHEALQGMVSPENTSFQPSVCVSDTPNAL 704
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|157951725|ref|NP_033949.2| catenin (cadherin
associated protein), alpha 2 isoform 2 [Mus musculus]
         (953 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

06876                                                                  30   6.8  
>06876
          Length = 1371

 Score = 29.6 bits (65), Expect = 6.8,   Method: Composition-based stats.
 Identities = 15/33 (45%), Positives = 21/33 (63%)
 Frame = +1

Query: 249 EAIAGISSAAQATSPTDEAKGHTGIGELAAALN 281
           EA++ I+ AA A   T + KG TG+G   AAL+
Sbjct: 85  EAVSAITLAASAALTTVDVKGATGLGGTTAALS 183
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|172072615|ref|NP_084429.2| MAK10 homolog, amino-acid
N-acetyltransferase subunit [Mus musculus]
         (725 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

28345                                                                  29   6.8  
>28345
          Length = 365

 Score = 28.9 bits (63), Expect = 6.8,   Method: Composition-based stats.
 Identities = 17/65 (26%), Positives = 32/65 (49%), Gaps = 1/65 (1%)
 Frame = -1

Query: 154 LKICDIAREKVNKAAVFEEEDFQSMTYGFKM-ANSVTDLRVTGMLKDVEDDLQRRVKSTR 212
           + +CD+    +N++     +  Q  T    +  N V ++ +TG L + E    R+V + R
Sbjct: 266 IPLCDVTAGILNQSLHHPRQSLQHSTAQRPLFRNRVENIEITGWLGNEEQSXLRQVFAQR 87

Query: 213 SRQGE 217
            R+GE
Sbjct: 86  QREGE 72
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|21312030|ref|NP_081014.1| RIKEN cDNA 1110007C09 [Mus
musculus]
         (183 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

03856                                                                  27   6.8  
04877                                                                  26   7.1  
06898                                                                  26   8.5  
>03856
          Length = 1292

 Score = 26.6 bits (57), Expect = 6.8,   Method: Compositional matrix adjust.
 Identities = 20/62 (32%), Positives = 32/62 (51%), Gaps = 4/62 (6%)
 Frame = -1

Query: 38  YYPQILTNKEAEKFRNPK--ASLRVRLCDLL-SHLQ-QRGERHCQEFYRALYIHAQPLHS 93
           Y P I ++ +  + R P   +SL V  C    S+ Q Q  +RH Q+F+  L+  A+   +
Sbjct: 908 YLPGICSSVQHSQLRVPDL*SSLLVTTCSSCPSYFQRQTLKRHTQQFFWLLFAFARNAKA 729

Query: 94  HL 95
           HL
Sbjct: 728 HL 723
>04877
          Length = 1400

 Score = 26.2 bits (56), Expect = 7.1,   Method: Compositional matrix adjust.
 Identities = 12/25 (48%), Positives = 15/25 (60%)
 Frame = +3

Query: 28   VDRIILQLNRYYPQILTNKEAEKFR 52
            +D+IIL+LN YY      K A  FR
Sbjct: 1320 LDKIILRLNTYYHAAPARKTASHFR 1394
>06898
          Length = 1979

 Score = 26.2 bits (56), Expect = 8.5,   Method: Compositional matrix adjust.
 Identities = 11/29 (37%), Positives = 18/29 (62%)
 Frame = +3

Query: 55  KASLRVRLCDLLSHLQQRGERHCQEFYRA 83
           +AS  V   D++ HLQ   E+H Q+F ++
Sbjct: 909 QASRNVAFRDIMYHLQGHAEKHLQQFRKS 995
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|74959788|ref|NP_080849.1| UPF3 regulator of nonsense
transcripts homolog B [Mus musculus]
         (472 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

18191                                                                  28   6.9  
>18191
          Length = 460

 Score = 28.5 bits (62), Expect = 6.9,   Method: Composition-based stats.
 Identities = 12/33 (36%), Positives = 19/33 (57%)
 Frame = +1

Query: 82  FFSNDTSLYPHMYARAYINFKNQEDILLFRDRF 114
           FF ++  +   + A   + F+ QED+ LFRD F
Sbjct: 247 FFRSNACILRXVLANVRLCFQLQEDLCLFRDEF 345
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|84794552|ref|NP_061346.2| phosphatidylethanolamine
binding protein 1 [Mus musculus]
         (187 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

03174                                                                  27   7.1  
>03174
          Length = 1459

 Score = 26.6 bits (57), Expect = 7.1,   Method: Compositional matrix adjust.
 Identities = 14/39 (35%), Positives = 21/39 (53%)
 Frame = +3

Query: 34  VDELGKVLTPTQVMNRPSSISWDGLDPGKLYTLVLTDPD 72
           VD++  +L     ++RP   +W G+  G   TL L DPD
Sbjct: 792 VDQVRSLLHQKAALSRPGLCTWPGVVRGAGPTLGLCDPD 908
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|225903402|ref|NP_036114.2| homer homolog 3 isoform 2
[Mus musculus]
         (356 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

31647                                                                  28   7.2  
>31647
          Length = 318

 Score = 27.7 bits (60), Expect = 7.2,   Method: Compositional matrix adjust.
 Identities = 27/72 (37%), Positives = 36/72 (50%), Gaps = 6/72 (8%)
 Frame = -3

Query: 122 DGG-----EFTSTGLALASHQVPPSPLVSTNGPGEEKLFRSQSADTPGPT-ERERLKKML 175
           DGG     E   +GL +   QVPPSPL   N   E+K +   SAD   PT +R+ L   L
Sbjct: 316 DGGHGAMIEALESGLPVDLSQVPPSPL--ENEETEDK-YVVVSADDCQPTGDRDELFTQL 146

Query: 176 SEGSVGEVQWEA 187
            +  V ++Q  A
Sbjct: 145 EQDMVKQIQTCA 110
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31541975|ref|NP_080536.2| tectonic family member 3
[Mus musculus]
         (595 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

16700                                                                  28   7.3  
>16700
          Length = 1234

 Score = 28.5 bits (62), Expect = 7.3,   Method: Compositional matrix adjust.
 Identities = 12/22 (54%), Positives = 15/22 (68%)
 Frame = +1

Query: 226  GLCAESNPAGFLESKSTTCPRF 247
            G+ A SN  GF+ S STTCP +
Sbjct: 988  GMSATSNHWGFISSDSTTCPLY 1053
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|63556710|ref|XP_357730.3| PREDICTED: similar to novel
androgen binding protein (Abp) family member [Mus musculus]
         (93 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

28817                                                                  25   7.3  
>28817
          Length = 393

 Score = 25.0 bits (53), Expect = 7.3,   Method: Compositional matrix adjust.
 Identities = 13/60 (21%), Positives = 28/60 (46%), Gaps = 2/60 (3%)
 Frame = +2

Query: 29  IKEDVRLFLNGTSEEYVEYVKQYKD--DPVILENTAKIKQCVDSTLTEEDKIHATTFIEK 86
           I+E   +    T  E + +V++  D   P+  ++ + I  C+DS   +   + AT  + +
Sbjct: 164 IREHPHITFEATKREAIRWVREDADTYHPIQQQSVSSINPCMDSVEAQLSXLAATXSLHE 343
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|30519953|ref|NP_848734.1| hypothetical protein
LOC69773 [Mus musculus]
         (266 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

20095                                                                  27   7.7  
>20095
          Length = 417

 Score = 26.9 bits (58), Expect = 7.7,   Method: Compositional matrix adjust.
 Identities = 16/59 (27%), Positives = 32/59 (54%)
 Frame = -3

Query: 208 HQLHSEANERLFEEKYKPIILTDDQVDQALWEEQVLQKERKDRLALSEADSLVQSDVSR 266
           HQ+  +    LFEE  + + +T     + L   +V+Q +    L   E+DS+V+++++R
Sbjct: 241 HQVSQQYRSVLFEENGERLDVTVTPAVEFLGVSRVIQHDTGRLLGRIESDSVVKNEIAR 65
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|88900515|ref|NP_082185.2| transmembrane protein 24
[Mus musculus]
         (706 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

02692                                                                  29   7.7  
>02692
          Length = 1526

 Score = 28.9 bits (63), Expect = 7.7,   Method: Compositional matrix adjust.
 Identities = 25/76 (32%), Positives = 33/76 (43%)
 Frame = -3

Query: 156  LSAEEVRFPISVTQQSPAAVSMETYHVTLTLPPTQLEVSLEEIPDEGLLVSWAFTDRPEL 215
            +SAEE++      QQS     M    V       QLE  L  I +EG +    F DR E 
Sbjct: 1389 VSAEELKSLEYQLQQSQKMADMYREQVI------QLEDELSRIREEGDVTREVFHDRSEK 1228

Query: 216  SLKVLPKLQTRERDEE 231
              K L  + +R +D E
Sbjct: 1227 MTKRLQLMNSRYQDLE 1180
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|94420266|ref|XP_001005685.1| PREDICTED: similar to
CTAGE family, member 5 isoform 1 [Mus musculus]
         (637 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

11942                                                                  28   7.7  
>11942
          Length = 2252

 Score = 28.5 bits (62), Expect = 7.7,   Method: Compositional matrix adjust.
 Identities = 19/50 (38%), Positives = 29/50 (58%), Gaps = 9/50 (18%)
 Frame = +1

Query: 214  ASMSTKC-----NLEDQIKKLEDDRSSLQT----AKAGLEDECKTLRQKV 254
            A + + C     NL ++ +K  D+R  L+     AKAG E+E KTLR+K+
Sbjct: 988  ADLKSTCDTLERNLNERKRKAVDERKKLEEEADEAKAGYEEEIKTLREKL 1137
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|119372290|ref|NP_666146.2| CTAGE family, member 5
[Mus musculus]
         (777 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

31742                                                                  29   7.8  
>31742
          Length = 860

 Score = 28.9 bits (63), Expect = 7.8,   Method: Compositional matrix adjust.
 Identities = 13/25 (52%), Positives = 14/25 (56%)
 Frame = -1

Query: 563 RAPSDRSLSPPWEQDRRMTAHPPPG 587
           R P     SP W Q  R+TA PPPG
Sbjct: 668 RCPWGGCRSPAWCQGPRLTARPPPG 594
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|51706216|ref|XP_485010.1| PREDICTED: hypothetical
protein LOC72421 isoform 1 [Mus musculus]
         (664 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

30337                                                                  29   7.8  
>30337
          Length = 493

 Score = 28.9 bits (63), Expect = 7.8,   Method: Compositional matrix adjust.
 Identities = 17/79 (21%), Positives = 35/79 (44%)
 Frame = -1

Query: 20  RLIRDSRYSEAVQLLSAEXXXXXXXXXXXXXXAYCYYRLQEFELAAECYEQLSQMHPELE 79
           +L    +Y +A+   +                A CY +L+ +ELA++  ++  ++   L 
Sbjct: 304 KLFAARKYEDAIHCYTKAIMKNPNTATYFTNRALCYIKLRNWELASQDCQRALELDRNLV 125

Query: 80  QYRLYQAQALYKACLYPEA 98
           +   +  QAL +  +Y EA
Sbjct: 124 KGHFFLGQALVELAMYDEA 68
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|94387111|ref|XP_996920.1| PREDICTED: similar to
CG9170-PA, isoform A isoform 3 [Mus musculus]
         (1471 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

30643                                                                  30   7.9  
>30643
          Length = 554

 Score = 30.0 bits (66), Expect = 7.9,   Method: Compositional matrix adjust.
 Identities = 26/72 (36%), Positives = 40/72 (55%), Gaps = 11/72 (15%)
 Frame = -2

Query: 977  QHLEEAKKEHTHLLETKQQLRRTIDDLRVRRVELESQVD-----LLQAQ------SQRLQ 1025
            Q L EAKK++ +L+E  Q ++  + +  VR  ELE Q+      L+Q Q      +QR+Q
Sbjct: 319  QGLNEAKKQNHNLMERLQTMQNDVSESEVRCAELEGQIRQLNNLLVQRQEAEQELNQRMQ 140

Query: 1026 KHLSSLEAEVQR 1037
            K  S  +A V+R
Sbjct: 139  KSQSEKQALVER 104
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|13385860|ref|NP_080634.1| ovary-specific acidic
protein [Mus musculus]
         (283 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

03430                                                                  27   8.0  
37675                                                                  27   8.5  
>03430
          Length = 1294

 Score = 27.3 bits (59), Expect = 8.0,   Method: Compositional matrix adjust.
 Identities = 14/31 (45%), Positives = 17/31 (54%)
 Frame = +2

Query: 198 GADTSQEGADTSQEGADTSQEGADTTKEEAD 228
           G+D   E  D  QE  D SQE  D +KE+ D
Sbjct: 809 GSDQPPEKTDQLQEKLDHSQEKRDRSKEKRD 901
>37675
          Length = 741

 Score = 26.9 bits (58), Expect = 8.5,   Method: Compositional matrix adjust.
 Identities = 10/24 (41%), Positives = 13/24 (54%)
 Frame = +3

Query: 88  ELQPLPGEKEEHVAEAEQVCSEPG 111
           EL P PG+ +   A A  +C  PG
Sbjct: 633 ELDPCPGDSDRQAAHAAALCGTPG 704
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|27597069|ref|NP_775482.1| PRUNEM1 [Mus musculus]
         (454 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

36173                                                                  28   8.0  
26951                                                                  28   8.3  
01494                                                                  28   8.4  
>36173
          Length = 947

 Score = 28.1 bits (61), Expect = 8.0,   Method: Compositional matrix adjust.
 Identities = 13/41 (31%), Positives = 23/41 (56%)
 Frame = +1

Query: 128 RPIEQKYCPPCHVSVELVGSCATLVTERILQGAPETLDRQT 168
           RP+ Q+ C PC ++ +++G   TLV + +   +   LD  T
Sbjct: 544 RPVTQE-CSPCELNYDVIGHVETLVNDTLHLASVLHLDNST 663
>26951
          Length = 463

 Score = 28.1 bits (61), Expect = 8.3,   Method: Compositional matrix adjust.
 Identities = 19/57 (33%), Positives = 25/57 (43%)
 Frame = +3

Query: 289 FNTQNEPVRQLAIFCPHEALRMTICGILERSTSPPLKLTPIPSTSPNLQAYHQGNTQ 345
           ++TQN+     A   P +    T CG+      P  +L P P   P LQ  HQ  TQ
Sbjct: 207 WHTQNQGRFPYATTAPSQY--GTWCGLPPDGRQPHGRLDPAPPQCPRLQRQHQERTQ 371
>01494
          Length = 2122

 Score = 28.1 bits (61), Expect = 8.4,   Method: Compositional matrix adjust.
 Identities = 16/53 (30%), Positives = 26/53 (49%)
 Frame = +3

Query: 195 SKYVEELEALFPDLPKRKDIFDSLQKAKFDVSGLTTEQMLRKDQKTVYRQGTK 247
           S +VEE+E    D+        SLQ+  FD+ G   E +  +  K+ +R  T+
Sbjct: 453 SNFVEEIET-HSDVNSDSMPLGSLQQGSFDIQGCLVEPLAPRGDKSAFRISTR 608
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|124487407|ref|NP_031593.2| bassoon protein [Mus
musculus]
         (3942 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

17181                                                                  31   8.1  
>17181
          Length = 428

 Score = 31.2 bits (69), Expect = 8.1,   Method: Compositional matrix adjust.
 Identities = 19/59 (32%), Positives = 29/59 (49%), Gaps = 4/59 (6%)
 Frame = -2

Query: 213 LCLNCQMQRALGMDMT---TAPRSKSQQQLHSPALSPAHS-PAKQPLGKPEQERSPRGP 267
           LC+N QM    G+D+T      +++SQ+ LH   +   HS P    +  P Q  + R P
Sbjct: 223 LCINGQMMELSGVDITQQEACDKAESQKNLHLLVVECRHSPPVAGEITPPHQTXADRAP 47
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|148747162|ref|NP_766208.2| vacuolar protein sorting
52 [Mus musculus]
         (723 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

36217                                                                  29   8.1  
10762                                                                  28   9.7  
>36217
          Length = 377

 Score = 28.9 bits (63), Expect = 8.1,   Method: Composition-based stats.
 Identities = 15/42 (35%), Positives = 25/42 (59%), Gaps = 5/42 (11%)
 Frame = +1

Query: 630 RLRGEEARVTQL-----IRGFGSSWKASVESLSQDVMRSFTN 666
           R R E+ R + +     +RG GSS + S+ S+   VM++F+N
Sbjct: 46  RRRQEDVRCSPIST*TRLRGVGSSCRLSLSSVCDSVMQTFSN 171
>10762
          Length = 547

 Score = 28.5 bits (62), Expect = 9.7,   Method: Composition-based stats.
 Identities = 15/43 (34%), Positives = 24/43 (55%)
 Frame = -1

Query: 378 FEALFRSQHYALLDNSCREYLFICEFFIVSGPAAHDLFHAVMG 420
           +  +F S +Y  +D     Y  +C  F++SGP AH+L H + G
Sbjct: 541 WSCVFCSHNY--VDMYIYVYDRVCGKFVLSGPIAHELRHLLRG 419
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|38348460|ref|NP_941009.1| mesenchymal stem cell
protein DSCD75 homolog [Mus musculus]
         (207 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

25720                                                                  27   8.1  
01930                                                                  27   8.4  
>25720
          Length = 619

 Score = 26.6 bits (57), Expect = 8.1,   Method: Compositional matrix adjust.
 Identities = 13/39 (33%), Positives = 20/39 (51%)
 Frame = -3

Query: 153 QHVLGTSPDRVVQHLCKRRVEPPELPEDLKHWISYNETS 191
            H+ G S    V  LC+R V PP LP    + + +++ S
Sbjct: 557 MHLYGLSVYYFVPSLCRRAVMPPPLPLIFPNDMFFSDIS 441
>01930
          Length = 812

 Score = 26.6 bits (57), Expect = 8.4,   Method: Compositional matrix adjust.
 Identities = 16/50 (32%), Positives = 21/50 (42%)
 Frame = -2

Query: 56  PSDLDLLLHMNNARYLREADVARAAHLTRCGVLGALRDLNAHTVLAASCA 105
           P  L    HM+   YL  A       + RCGV+ +LR+       A  CA
Sbjct: 364 PDSLXARKHMHAILYLMRASXGSQCRVWRCGVMXSLRETFKSRRAAEFCA 215
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|40254163|ref|NP_083685.2| mitochondrial fission
factor [Mus musculus]
         (291 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

23127                                                                  27   8.1  
>23127
          Length = 1376

 Score = 27.3 bits (59), Expect = 8.1,   Method: Compositional matrix adjust.
 Identities = 21/58 (36%), Positives = 30/58 (51%), Gaps = 5/58 (8%)
 Frame = +2

Query: 128 RSMSENAVRQNGQLVRNDSIVTPSPPQAR-----VCPPHMLPEDGANLSSARGILSLI 180
           R+M    +    Q + NDS ++PSPP+A      + PP+ LP      S  RGIL L+
Sbjct: 860 RNMRFCFLPLTTQELTNDSGLSPSPPRAVEPCF*LSPPYRLPH-----SDFRGILPLL 1018
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|7305631|ref|NP_038869.1| vacuolar protein sorting 45
[Mus musculus]
         (570 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

07187                                                                  28   8.3  
04441                                                                  28   9.3  
32992                                                                  28   9.4  
>07187
          Length = 1996

 Score = 28.5 bits (62), Expect = 8.3,   Method: Compositional matrix adjust.
 Identities = 9/18 (50%), Positives = 13/18 (72%)
 Frame = -2

Query: 139 LNILGCCQGRNWDPAQLS 156
           LN+  CC  RNW P+++S
Sbjct: 57  LNVFECCTFRNWSPSRIS 4
>04441
          Length = 2557

 Score = 28.1 bits (61), Expect = 9.3,   Method: Compositional matrix adjust.
 Identities = 14/35 (40%), Positives = 19/35 (54%)
 Frame = -2

Query: 348 LEVSEVEQELACQNDHSSALQNVKRLLQNPKVTEF 382
           L V  V QEL C+N H  + + V  +LQN  V + 
Sbjct: 246 LYVQAVVQELTCKNKHKQSTRQVSSVLQNKLVKQL 142
>32992
          Length = 491

 Score = 28.1 bits (61), Expect = 9.4,   Method: Compositional matrix adjust.
 Identities = 25/104 (24%), Positives = 48/104 (46%), Gaps = 8/104 (7%)
 Frame = +1

Query: 12  SKMIEDSGPGMKVLLMDKETTGIVSMVYTQSEILQKE--VYLFERIDSQNREIMKHLKAI 69
           S  I     G  +L  D  T   V+  YT S ++ ++   +LF++     R   +H++  
Sbjct: 130 STHIHRRKSGSHILHTDVHTHS-VTHAYTYSPLVYRKNLCFLFKK----GRFNQRHIRTS 294

Query: 70  CFLRPT------KENVEYLIQELRRPKYSIYFIYFSNVISKSDV 107
            +L  +      K+N +Y+   L + + S +F+Y +N+I    V
Sbjct: 295 AYLHKSEIPKAWKQNTKYVFNLL*QGEKSNHFVYNTNIIQSRTV 426
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|29789333|ref|NP_598611.1| COMM domain containing 7
[Mus musculus]
         (210 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

05048                                                                  27   8.6  
>05048
          Length = 442

 Score = 26.6 bits (57), Expect = 8.6,   Method: Compositional matrix adjust.
 Identities = 16/41 (39%), Positives = 22/41 (53%), Gaps = 1/41 (2%)
 Frame = +2

Query: 92  VRTDLQTLGLSEEKATYF-SEKWKQNASTLAQWAMGQTLMV 131
           ++T LQ    S+ K  Y  SEK  Q ++   QW  G TL+V
Sbjct: 71  MQTRLQGCESSQNKIAYLNSEKKXQGSAVGPQWGPGATLLV 193
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|84370347|ref|NP_001033698.1| microtubule-associated
protein tau isoform a [Mus musculus]
         (430 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

16645                                                                  28   8.6  
>16645
          Length = 749

 Score = 27.7 bits (60), Expect = 8.6,   Method: Compositional matrix adjust.
 Identities = 23/85 (27%), Positives = 38/85 (44%), Gaps = 7/85 (8%)
 Frame = -3

Query: 48  PGSETSDAKSTPTAEDVTAPLVD-------ERAPDKQAAAQPHTEIPEGITAEEAGIGDT 100
           PGSET         EDV  P ++       E+  +K    +   ++ E + A + G+GD+
Sbjct: 654 PGSETQ----PKEGEDVHVPAINLSDKVNTEKLREKMLQMKEKRKVKEKLKAVK-GLGDS 490

Query: 101 PNQEDQAAGHVTQARVASKDRTGND 125
            ++ED     V ++R   K R   D
Sbjct: 489 DSEEDDVFAWVKKSRKDEKQRKMAD 415
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|89111939|ref|NP_081546.1| exocyst complex component 1
[Mus musculus]
         (901 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

36712                                                                  29   8.6  
>36712
          Length = 486

 Score = 28.9 bits (63), Expect = 8.6,   Method: Compositional matrix adjust.
 Identities = 23/91 (25%), Positives = 36/91 (39%)
 Frame = -3

Query: 354 LASHLNNVFVQQGHDQSSTLAQHSVELTLPNHHPFHRDLLRYAKLMEWLKSTDYGKYEGL 413
           LA+  + VF + G   S                   + L+RY K    LKS  Y K E L
Sbjct: 328 LANGFDKVFTRGGKGYSVLFTS------------LFKGLIRYVKSQPKLKSLYYDKLENL 185

Query: 414 TKNYMDYLSRLYEREIKDFFEVAKMKMTGTS 444
             N M+Y +R ++    +F      ++  T+
Sbjct: 184 LPNLMEYAARSFDVNDGEFSHTYPWRLXTTN 92
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|46852193|ref|NP_083596.2| progesterone-induced
blocking factor 1 isoform a [Mus musculus]
         (756 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

04618                                                                  29   8.7  
>04618
          Length = 1663

 Score = 28.9 bits (63), Expect = 8.7,   Method: Compositional matrix adjust.
 Identities = 35/116 (30%), Positives = 58/116 (50%), Gaps = 11/116 (9%)
 Frame = -3

Query: 397  SASREMYERENRNLREARDNALAEKNRAVAAE-KDALGKHEQLLD----------RYREL 445
            S  R++  +ENR L++      A++N+ + AE +DAL + E L D          R  ++
Sbjct: 1517 SRGRDICVQENRRLQDDL-TVTAKENQKLNAELQDALAEREALKDQVQKYILEVRRVEDM 1341

Query: 446  QLSTESKVSEFLHQSKLKSFESERVQLLQEETARNLTQCQLECEKYQKKLEVLTKE 501
              + E++ S+ L Q +  S E+E+ Q          T  QLE E    +LE++TKE
Sbjct: 1340 LANKEAERSDLLEQYRKLSLEAEQFQ---------TTSHQLESEGSNMRLEIMTKE 1200
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|21314832|ref|NP_647458.1| UDP-glucose
pyrophosphorylase 2 [Mus musculus]
         (508 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

36200                                                                  28   8.8  
31411                                                                  28   8.8  
>36200
          Length = 446

 Score = 28.1 bits (61), Expect = 8.8,   Method: Composition-based stats.
 Identities = 17/60 (28%), Positives = 27/60 (45%)
 Frame = -2

Query: 159 LVLMNSFNTDEDTKKILQKYNHCRVKIYTFNQSRYPRINKESLLPIAKDVSYSGENTEAW 218
           ++ +   +T + T KIL  YNH  + I        PRI K  L  +   V  + + T +W
Sbjct: 388 MMRLTHIHTHKHTPKILHMYNHTNIPIVCTVLGAKPRIRK*FLSNMDSSVFCTLDCTSSW 209
>31411
          Length = 1547

 Score = 28.1 bits (61), Expect = 8.8,   Method: Compositional matrix adjust.
 Identities = 15/58 (25%), Positives = 27/58 (46%)
 Frame = +3

Query: 167 TDEDTKKILQKYNHCRVKIYTFNQSRYPRINKESLLPIAKDVSYSGENTEAWYPPGHG 224
           T++ TK IL+ ++ C   I+   + R           ++K +  S    +AW+ P HG
Sbjct: 114 TEQ*TKYILKHFSQCLAYIHNLGRGR-----------VSKPIVQSRHTHQAWHLPTHG 254
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6753294|ref|NP_033948.1| catenin alpha 1 [Mus
musculus]
         (906 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

27722                                                                  29   8.8  
>27722
          Length = 434

 Score = 28.9 bits (63), Expect = 8.8,   Method: Compositional matrix adjust.
 Identities = 27/98 (27%), Positives = 46/98 (46%), Gaps = 1/98 (1%)
 Frame = +1

Query: 286 DKQIIVDPLSFSEERFRPSLEERLESIISGAALMADSSCTRDDRRERIVAECNAVRQALQ 345
           +++++VD L    +R R  L        SG   +A  +   ++ R  + AE +++R  L 
Sbjct: 94  EQRLLVDKLQREVDRLREQL--------SGEKQIA--AVEENEARHSLEAEVSSLRSQLS 243

Query: 346 DLLSEY-MGNAGRKERSDALNSAIDKMTKKTRDLRRQL 382
           DL   + M  A     +D     +D +T   RDL+RQL
Sbjct: 244 DLRGHHSMLQAD----NDQYQQVLDSLTTANRDLKRQL 345
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|10946978|ref|NP_067516.1| crystallin, beta A2 [Mus
musculus]
         (197 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

00560                                                                  26   8.9  
>00560
          Length = 886

 Score = 26.2 bits (56), Expect = 8.9,   Method: Compositional matrix adjust.
 Identities = 16/50 (32%), Positives = 22/50 (44%), Gaps = 7/50 (14%)
 Frame = -3

Query: 13  CLTLWDEEDFQGRRCRLLSDCANVCERGALRRVRSV-------KVENGAW 55
           CL+ W+  D    +   LS C N C   A+   R +       KV+NG W
Sbjct: 575 CLSSWNIADDVPDQSNDLSQCTNHC*HCAVNPHRKIDGGEHGSKVDNGEW 426
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|10946672|ref|NP_067326.1| crystallin, beta A4 [Mus
musculus]
         (196 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

14718                                                                  26   9.0  
>14718
          Length = 475

 Score = 26.2 bits (56), Expect = 9.0,   Method: Compositional matrix adjust.
 Identities = 13/47 (27%), Positives = 20/47 (42%)
 Frame = +2

Query: 11  HWRMVVWDEEGFQGRRHEFTAECPSVLELGFETVRSLKVLSGAWVGF 57
           HW+  V   + F+ R       CP+ L  G  TV ++     +W G 
Sbjct: 206 HWQKAVCGHQWFKIRVRSCRVRCPTRLCXGPPTVSTVHQRPTSWSGL 346
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|163644329|ref|NP_033826.2| apolipoprotein E [Mus
musculus]
         (311 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

36482                                                                  27   9.2  
>36482
          Length = 686

 Score = 26.9 bits (58), Expect = 9.2,   Method: Compositional matrix adjust.
 Identities = 24/99 (24%), Positives = 51/99 (51%), Gaps = 8/99 (8%)
 Frame = +2

Query: 31  QSNQPWEQALNRFWDYLRWVQTLSD--------QVQEELQSSQVTQELTALMEDTMTEVK 82
           Q   PW++    + D   +V +++D        QV+ +++S + +  LTA++    T++ 
Sbjct: 128 QGTYPWKEGYALWADCFVFVYSINDRQSYEELVQVKRQVESVRKSTSLTAVLAANKTDLL 307

Query: 83  AYKKELEEQLGPVAEETRARLGKEVQAAQARLGADMEDL 121
             ++  +++   +AEE   RL  EV A++   G+ ME +
Sbjct: 308 HDRQVTQKEGEDLAEEIGCRL-YEVSASE---GSQMEAI 412
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|166235131|ref|NP_766551.3| hypothetical protein
LOC68617 isoform 2 [Mus musculus]
         (1945 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

03868                                                                  30   9.4  
>03868
          Length = 1865

 Score = 30.0 bits (66), Expect = 9.4,   Method: Compositional matrix adjust.
 Identities = 30/95 (31%), Positives = 46/95 (48%), Gaps = 3/95 (3%)
 Frame = -2

Query: 1130 LFRALKALLEDFRSELREDEHARLRLQQQYASDKAAWDVEWAVLKCRLEQ-LEEKTEKSL 1188
            L R   +    + SELR D  + LR ++   +   A D EWA +K RLE+ L  + +  +
Sbjct: 1378 LHRVCYSFHSSY-SELR-DLVSLLRPRRVLPNVLPASDTEWAQVKXRLEKFLTYRHKHHM 1205

Query: 1189 GELDSSAEGK--GALKKEREVHQKLLADSHSLVMD 1221
                 +   K  G LK++R+      +DS SLV D
Sbjct: 1204 APTGDTTAAKPLGLLKRKRQPSVHSESDSDSLVFD 1100
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|33468885|ref|NP_033916.1| calcyclin binding protein
[Mus musculus]
         (229 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

01305                                                                  27   9.4  
>01305
          Length = 2257

 Score = 26.6 bits (57), Expect = 9.4,   Method: Compositional matrix adjust.
 Identities = 10/27 (37%), Positives = 20/27 (74%)
 Frame = +3

Query: 192 LMNVLKKIYEDGDDDMKRTINKAWVES 218
           L  + ++IY DG+D++K+ + K++ ES
Sbjct: 189 LNQLFQQIYSDGNDEVKKAMMKSFSES 269
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|30519943|ref|NP_848729.1| sorting and assembly
machinery component 50 homolog [Mus musculus]
         (469 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

00934                                                                  28   9.6  
>00934
          Length = 1569

 Score = 27.7 bits (60), Expect = 9.6,   Method: Compositional matrix adjust.
 Identities = 15/45 (33%), Positives = 19/45 (42%)
 Frame = -2

Query: 394 HFFLNAGNLCNLNYGEGPKAHIRKLAECIRWSYGAGVVLRLGNIA 438
            FF     +C      G     RK  E I W YG GV++ LG + 
Sbjct: 809 RFFSKFTEICKSRSAMGQSCEFRKSVEKILWVYG-GVIVFLGQLT 678
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|30725710|ref|NP_849205.1| transmembrane and
coiled-coil domains 2 [Mus musculus]
         (706 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

03419                                                                  28   9.9  
>03419
          Length = 1891

 Score = 28.5 bits (62), Expect = 9.9,   Method: Compositional matrix adjust.
 Identities = 18/39 (46%), Positives = 22/39 (56%), Gaps = 2/39 (5%)
 Frame = -2

Query: 127 PEMHRVSYAVSLHDLPARPTAF--NRVLQQIRSRPSIKR 163
           P +H +   VSL  LPARP A   N +   IRS+  IKR
Sbjct: 147 PRLHALIPTVSLRALPARPGALFGNHMQVTIRSQAEIKR 31
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31982305|ref|NP_848787.2| sec1 family domain
containing 2 isoform b [Mus musculus]
         (477 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

36719                                                                  28   9.9  
>36719
          Length = 518

 Score = 27.7 bits (60), Expect = 9.9,   Method: Compositional matrix adjust.
 Identities = 12/25 (48%), Positives = 13/25 (52%)
 Frame = +3

Query: 29 DAACAESLHWSCGSSRLLEAVKGPA 53
          +A C    HWSCG  R     KGPA
Sbjct: 36 NARCRLWRHWSCGRGRCQGVAKGPA 110
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6677845|ref|NP_033144.1| retinal S-antigen [Mus
musculus]
         (403 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6678768|ref|NP_032564.1| myristoylated alanine rich
protein kinase C substrate [Mus musculus]
         (309 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6679158|ref|NP_032775.1| nucleobindin 1 [Mus
musculus]
         (455 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6679337|ref|NP_032876.1| phosphatidylinositol
transfer protein, alpha [Mus musculus]
         (271 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6679339|ref|NP_032877.1| phosphatidylinositol
transfer protein, membrane-associated 1 isoform 1 [Mus musculus]
         (1243 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6753098|ref|NP_033824.1| apolipoprotein B mRNA
editing enzyme, catalytic polypeptide 2 [Mus musculus]
         (224 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6755040|ref|NP_035202.1| profilin 1 [Mus musculus]
         (140 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6755112|ref|NP_035255.1| phospholipid transfer
protein [Mus musculus]
         (493 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6755592|ref|NP_035560.1| synuclein, gamma [Mus
musculus]
         (123 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|6996911|ref|NP_031520.1| argininosuccinate synthetase
[Mus musculus]
         (412 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|7305291|ref|NP_038632.1| metaxin 1 [Mus musculus]
         (317 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|7305507|ref|NP_038697.1| synaptosomal-associated
protein 91 [Mus musculus]
         (901 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|8394460|ref|NP_058659.1| tropomodulin 3 [Mus
musculus]
         (352 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|9790261|ref|NP_062652.1| Trk-fused [Mus musculus]
         (397 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|9903607|ref|NP_064337.1| canopy 2 homolog [Mus
musculus]
         (182 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|12963675|ref|NP_075918.1| OCIA domain containing 1
[Mus musculus]
         (247 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|12963789|ref|NP_076184.1| crystallin, beta B1 [Mus
musculus]
         (250 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|12963799|ref|NP_076210.1| ATPase, H+ transporting, V1
subunit D [Mus musculus]
         (247 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|13173473|ref|NP_035300.1| prion protein [Mus
musculus]
         (254 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|13384806|ref|NP_079693.1| COMM domain containing 4
[Mus musculus]
         (199 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|13385536|ref|NP_080310.1| SVH protein [Mus musculus]
         (306 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|13385970|ref|NP_080762.1| tectonic family member 2
[Mus musculus]
         (700 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|13386026|ref|NP_080804.1| hypothetical protein
LOC68045 [Mus musculus]
         (244 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|13386062|ref|NP_080841.1| apolipoprotein O-like [Mus
musculus]
         (265 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|13626040|ref|NP_112462.1| A kinase (PRKA) anchor
protein (gravin) 12 [Mus musculus]
         (1684 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|13994209|ref|NP_114083.1| WASP family 1 [Mus
musculus]
         (559 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|15426055|ref|NP_203534.1| coatomer protein complex,
subunit beta 1 [Mus musculus]
         (953 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|15809030|ref|NP_291088.1| synuclein, beta [Mus
musculus]
         (133 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|17505218|ref|NP_510963.1| growth hormone inducible
transmembrane protein [Mus musculus]
         (346 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|17921980|ref|NP_084022.1| component of oligomeric
golgi complex 2 [Mus musculus]
         (731 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|18700026|ref|NP_570955.1| oxidation resistance 1
isoform A [Mus musculus]
         (778 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|19526842|ref|NP_598544.1| prostaglandin E synthase 2
[Mus musculus]
         (384 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|19527154|ref|NP_598698.1| hypothetical protein
LOC101314 [Mus musculus]
         (75 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|21312151|ref|NP_081161.1| putative breast
adenocarcinoma marker [Mus musculus]
         (222 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|21312460|ref|NP_081527.1| hypothetical protein
LOC69894 [Mus musculus]
         (120 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|21312676|ref|NP_083116.1| armadillo repeat-containing
protein [Mus musculus]
         (282 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|21312816|ref|NP_080618.1| hypothetical protein
LOC67726 [Mus musculus]
         (490 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|21312946|ref|NP_080470.1| hypothetical protein
LOC67490 [Mus musculus]
         (793 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|21313286|ref|NP_084035.1| hypothetical protein
LOC76824 [Mus musculus]
         (289 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|21313290|ref|NP_080070.1| electron transferring
flavoprotein, dehydrogenase [Mus musculus]
         (616 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|21313344|ref|NP_080392.1| Bardet-Biedl syndrome 2
[Mus musculus]
         (721 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|21536264|ref|NP_659155.1| SH3-domain GRB2-like
(endophilin) interacting protein 1 [Mus musculus]
         (806 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|21553113|ref|NP_660137.1| WAS protein family, member
3 [Mus musculus]
         (501 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|21704156|ref|NP_663550.1| caldesmon 1 [Mus musculus]
         (530 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|21704204|ref|NP_663573.1| nucleoredoxin-like 1 [Mus
musculus]
         (217 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|22122481|ref|NP_666126.1| cerebral cavernous
malformation 2 homolog [Mus musculus]
         (453 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|22122785|ref|NP_666335.1| complexin III [Mus
musculus]
         (158 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|22507389|ref|NP_683724.1| transformed mouse 3T3 cell
double minute 1 isoform 2 [Mus musculus]
         (708 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|26986541|ref|NP_758460.1| dynein cytoplasmic 2 light
intermediate chain 1 [Mus musculus]
         (351 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|28076935|ref|NP_081427.1| dynactin 2 [Mus musculus]
         (402 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|28461135|ref|NP_780408.1| heat shock protein 12A [Mus
musculus]
         (675 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|29243986|ref|NP_808280.1| catenin (cadherin
associated protein), alpha 3 [Mus musculus]
         (895 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|30352008|ref|NP_080016.1| coiled-coil domain
containing 104 [Mus musculus]
         (343 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|30519925|ref|NP_848720.1| NOP16 nucleolar protein
homolog [Mus musculus]
         (178 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31560247|ref|NP_079758.2| tumor protein D52-like 2
[Mus musculus]
         (220 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31980726|ref|NP_082408.2| phosphoglucomutase 2 [Mus
musculus]
         (562 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31981677|ref|NP_620087.2| protein phosphatase 2A,
regulatory subunit B (PR 53) [Mus musculus]
         (323 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31982038|ref|NP_758490.2| hypothetical protein
LOC234797 [Mus musculus]
         (407 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31982233|ref|NP_080278.3| LYRIC [Mus musculus]
         (579 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|31982330|ref|NP_032172.3| Golgi autoantigen, golgin
subfamily a, 3 [Mus musculus]
         (1447 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|33468999|ref|NP_081241.1|
catechol-O-methyltransferase domain containing 1 [Mus musculus]
         (262 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|33859560|ref|NP_034403.1| guanosine diphosphate (GDP)
dissociation inhibitor 1 [Mus musculus]
         (447 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|33942089|ref|NP_898841.1| ataxin 2-like [Mus
musculus]
         (1049 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|34328219|ref|NP_038751.2| podocalyxin-like [Mus
musculus]
         (503 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|34328251|ref|NP_062787.2| drebrin 1 [Mus musculus]
         (660 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|37360977|ref|NP_808482.2| ELKS/RAB6-interacting/CAST
family member 2 [Mus musculus]
         (1002 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|39930453|ref|NP_082948.1| hypothetical protein
LOC73873 [Mus musculus]
         (448 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|39930457|ref|NP_084014.1| clusterin associated
protein 1 [Mus musculus]
         (413 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|42558248|ref|NP_058019.2| cytoplasmic
activation/proliferation-associated protein 1 isoform a [Mus musculus]
         (707 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|45598372|ref|NP_081671.1| brain abundant, membrane
attached signal protein 1 [Mus musculus]
         (226 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|47059143|ref|NP_081240.1| coiled-coil domain
containing 124 [Mus musculus]
         (217 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|47271400|ref|NP_082091.2| hypothetical protein
LOC71517 [Mus musculus]
         (963 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|47607490|ref|NP_001001303.1|
glyceraldehyde-3-phosphate dehydrogenase [Mus musculus]
         (333 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|50582545|ref|NP_001002764.1| telomerase subunit EST1A
[Mus musculus]
         (1418 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|51243034|ref|NP_780698.2| oxysterol-binding
protein-like protein 8 isoform a [Mus musculus]
         (889 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|51708179|ref|XP_485258.1| PREDICTED: hypothetical
protein LOC213582 isoform 1 [Mus musculus]
         (646 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|54261813|ref|NP_001005767.1| presenilin associated,
rhomboid-like [Mus musculus]
         (377 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|58037467|ref|NP_084028.1| Bri3 binding protein [Mus
musculus]
         (253 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|60097931|ref|NP_084248.2| ermin, ERM-like protein
[Mus musculus]
         (281 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|60593063|ref|NP_705768.3| glycosyltransferase [Mus
musculus]
         (580 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|62526118|ref|NP_780660.1| cytoskeleton-associated
protein 4 [Mus musculus]
         (575 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|63147418|ref|NP_082994.1| TRAF3 interacting protein 1
[Mus musculus]
         (625 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|63477564|ref|XP_129477.5| PREDICTED: calmodulin
regulated spectrin-associated protein 1-like 1 isoform 1 [Mus
musculus]
         (1472 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|66730553|ref|NP_001019376.1| 82-kD FMRP Interacting
Protein [Mus musculus]
         (692 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|67972419|ref|NP_001020098.1| Pitpnm family member 3
isoform 1 [Mus musculus]
         (974 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|68226735|ref|NP_777357.2| hypothetical protein
LOC215708 [Mus musculus]
         (600 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|70608194|ref|NP_001020432.1| tumor protein D52
isoform 1 [Mus musculus]
         (247 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|70778812|ref|NP_780421.2| transmembrane protein 65
[Mus musculus]
         (234 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|70909327|ref|NP_034069.2| COP9 (constitutive
photomorphogenic) homolog, subunit 2 [Mus musculus]
         (443 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|75677480|ref|NP_001028493.1| hypothetical protein
LOC234740 [Mus musculus]
         (315 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|82933646|ref|XP_125775.5| PREDICTED: transmembrane
protein 1 isoform 1 [Mus musculus]
         (1258 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|83649709|ref|NP_058539.2| ataxin 10 [Mus musculus]
         (475 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|83649762|ref|NP_001032846.1| hypothetical protein
LOC68767 [Mus musculus]
         (475 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|84042521|ref|NP_001033320.1| barrier to
autointegration factor 1 [Mus musculus]
         (89 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|84452161|ref|NP_653097.2| COMM domain containing 1
[Mus musculus]
         (188 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|85702001|ref|NP_001028648.1| AHNAK nucleoprotein 2
[Mus musculus]
         (770 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|86198339|ref|NP_848893.2| hypothetical protein
LOC320271 [Mus musculus]
         (606 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|94158994|ref|NP_031492.2| apoptosis inhibitor 5 [Mus
musculus]
         (504 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|94368414|ref|XP_001001384.1| PREDICTED: similar to
tankyrase 1-binding protein of 182 kDa [Mus musculus]
         (1720 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|94394415|ref|XP_989248.1| PREDICTED: similar to AHNAK
nucleoprotein isoform 1 [Mus musculus]
         (900 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|94399931|ref|XP_001002810.1| PREDICTED: SET binding
factor 1 [Mus musculus]
         (1954 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|94405719|ref|XP_001004854.1| PREDICTED: hypothetical
protein LOC68505 [Mus musculus]
         (782 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|109638747|ref|NP_001035916.1| synuclein, alpha [Mus
musculus]
         (140 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|110350660|ref|NP_084108.1| DDRGK domain containing 1
[Mus musculus]
         (315 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|110625902|ref|NP_082293.1| N-ethylmaleimide sensitive
fusion protein attachment protein gamma [Mus musculus]
         (312 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|110626050|ref|NP_083707.1| thioesterase superfamily
member 4 [Mus musculus]
         (230 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|113865877|ref|NP_001038979.1| AT-hook transcription
factor [Mus musculus]
         (1404 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|116089329|ref|NP_061361.2| Snap-25-interacting
protein [Mus musculus]
         (1217 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|124244040|ref|NP_653128.2| eukaryotic translation
initiation factor 3, subunit J [Mus musculus]
         (261 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|125660458|ref|NP_848766.2| solute carrier family 30
(zinc transporter), member 9 [Mus musculus]
         (567 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|134053913|ref|NP_542121.2| proteasome 26S non-ATPase
subunit 5 [Mus musculus]
         (504 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|148540106|ref|NP_032676.2| methylmalonyl-Coenzyme A
mutase [Mus musculus]
         (748 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|148747189|ref|NP_032659.2| microtubule-associated
protein 4 [Mus musculus]
         (1125 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|149233880|ref|XP_897716.2| PREDICTED: GPI deacylase
[Mus musculus]
         (922 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|149249247|ref|XP_980286.2| PREDICTED: calmodulin
regulated spectrin-associated protein 1 [Mus musculus]
         (1603 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|149253148|ref|XP_205950.7| PREDICTED: hypothetical
protein [Mus musculus]
         (551 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|149255287|ref|XP_355790.4| PREDICTED: SEC15-like 2
isoform 1 [Mus musculus]
         (814 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|149260125|ref|XP_001000297.2| PREDICTED: KIAA1009
protein isoform 5 [Mus musculus]
         (1324 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|153791438|ref|NP_660258.2| Alstrom syndrome 1 [Mus
musculus]
         (3251 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|154240716|ref|NP_032428.2| integrin alpha V [Mus
musculus]
         (1044 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|157266281|ref|NP_079977.3| trafficking protein
particle complex 5 [Mus musculus]
         (188 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|157951731|ref|NP_001001454.2| tweety 1 isoform 1 [Mus
musculus]
         (460 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|158937310|ref|NP_001008423.2| hypothetical protein
LOC380768 [Mus musculus]
         (706 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|158966667|ref|NP_848805.2| RAB3 GTPase activating
protein subunit 1 [Mus musculus]
         (981 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|159110754|ref|NP_038609.3| component of oligomeric
golgi complex 1 [Mus musculus]
         (980 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|160298207|ref|NP_034452.3| glyceronephosphate
O-acyltransferase [Mus musculus]
         (678 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|168823441|ref|NP_001028431.2| coiled-coil domain
containing 109A [Mus musculus]
         (350 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|170014712|ref|NP_766018.3| sphingosine kinase type
1-interacting protein [Mus musculus]
         (1658 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|170763496|ref|NP_076151.2| pericentriolar material 1
[Mus musculus]
         (2025 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|225007593|ref|NP_034573.2| heme oxygenase (decycling)
2 [Mus musculus]
         (315 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


 
BLAST Search Results

TBLASTN 2.2.18 [Mar-02-2008]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= gi|225543273|ref|NP_659190.3| microtubule-associated
protein 7 domain containing 1 isoform 1 [Mus musculus]
         (846 letters)

Database: contigs50plus 
           39,407 sequences; 28,359,218 total letters

Searching..................................................done

 ***** No hits found ******


  Database: contigs50plus
    Posted date:  Aug 11, 2009  9:57 AM
  Number of letters in database: 28,359,218
  Number of sequences in database:  39,407
  
Lambda     K      H
   0.321    0.138    0.411 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 39407
Number of Hits to DB: 38,046,015,466
Number of extensions: 515810891
Number of successful extensions: 2334886
Number of sequences better than 10.0: 31366
Number of HSP's gapped: 2313548
Number of HSP's successfully gapped: 51115
Length of database: 9,453,072
Neighboring words threshold: 13
Window for multiple hits: 40
X1: 15 ( 6.9 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.4 bits)
S2: 38 (19.2 bits)